# --- full sequence ---- --- best 1 domain ---- --- domain number estimation ---- # target name accession query name accession E-value score bias E-value score bias exp reg clu ov env dom rep inc description of target #------------------- ---------- -------------------- ---------- --------- ------ ----- --------- ------ ----- --- --- --- --- --- --- --- --- --------------------- DUF2946 PF11162.8 AIN95102.1 - 1.5e-17 64.3 1.3 3.3e-17 63.2 1.3 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2946) Shisa PF13908.6 AIN95102.1 - 0.0036 17.6 0.0 0.0099 16.1 0.0 1.7 2 0 0 2 2 2 1 Wnt and FGF inhibitory regulator Orthoreo_P10 PF07204.11 AIN95102.1 - 0.03 14.3 0.2 0.09 12.7 0.2 1.8 1 0 0 1 1 1 0 Orthoreovirus membrane fusion protein p10 MAP17 PF15807.5 AIN95102.1 - 0.042 14.1 0.0 0.076 13.3 0.0 1.4 1 0 0 1 1 1 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 Rhabdo_glycop PF00974.18 AIN95102.1 - 0.089 11.2 1.8 0.13 10.7 0.5 1.8 2 0 0 2 2 2 0 Rhabdovirus spike glycoprotein Hum_adeno_E3A PF05393.11 AIN95102.1 - 0.089 12.8 0.5 0.22 11.5 0.5 1.7 1 0 0 1 1 1 0 Human adenovirus early E3A glycoprotein EphA2_TM PF14575.6 AIN95102.1 - 0.15 13.0 0.0 0.69 10.8 0.0 1.9 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Tweety PF04906.13 AIN95102.1 - 0.41 9.3 5.1 0.32 9.6 0.7 2.0 2 0 0 2 2 2 0 Tweety Exo_endo_phos PF03372.23 AIN95103.1 - 1.4e-06 28.0 0.0 4.3e-06 26.4 0.0 1.9 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family DELLA PF12041.8 AIN95103.1 - 0.032 14.1 0.0 0.075 12.9 0.0 1.5 1 0 0 1 1 1 0 Transcriptional regulator DELLA protein N terminal TPR_21 PF09976.9 AIN95103.1 - 0.14 11.8 4.9 0.035 13.8 1.7 1.5 2 0 0 2 2 2 0 Tetratricopeptide repeat-like domain Kinesin PF00225.23 AIN95104.1 - 1e-93 313.9 0.0 1.4e-93 313.5 0.0 1.1 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 AIN95104.1 - 5.8e-15 55.5 0.0 1.2e-14 54.5 0.0 1.5 1 0 0 1 1 1 1 Microtubule binding SAM_1 PF00536.30 AIN95104.1 - 0.016 15.6 0.0 0.029 14.8 0.0 1.5 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) Arg_decarbox_C PF17944.1 AIN95104.1 - 0.079 13.5 2.0 0.26 11.9 0.6 2.4 2 0 0 2 2 2 0 Arginine decarboxylase C-terminal helical extension BLOC1_2 PF10046.9 AIN95104.1 - 0.15 12.4 1.4 0.37 11.1 1.4 1.7 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 GYF PF02213.16 AIN95105.1 - 0.0015 18.1 0.1 0.0026 17.4 0.1 1.3 1 0 0 1 1 1 1 GYF domain CPSase_L_D2 PF02786.17 AIN95106.1 - 1.9e-77 259.6 1.1 2.9e-77 258.9 0.5 1.6 2 0 0 2 2 2 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.22 AIN95106.1 - 1.3e-43 148.0 0.4 3.7e-43 146.6 0.1 1.9 2 0 0 2 2 2 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 AIN95106.1 - 2.2e-36 124.2 0.0 7.5e-36 122.5 0.0 2.0 2 0 0 2 2 1 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.22 AIN95106.1 - 2.9e-15 55.9 3.3 2.9e-15 55.9 3.3 2.1 2 0 0 2 2 2 1 Biotin-requiring enzyme PCC_BT PF18140.1 AIN95106.1 - 1.4e-09 38.4 0.1 3.7e-09 37.0 0.1 1.6 1 0 0 1 1 1 1 Propionyl-coenzyme A carboxylase BT domain ATP-grasp PF02222.22 AIN95106.1 - 1.2e-08 34.7 1.0 3.1e-08 33.4 0.3 2.0 2 0 0 2 2 2 1 ATP-grasp domain Dala_Dala_lig_C PF07478.13 AIN95106.1 - 2.7e-06 27.1 0.3 6e-06 25.9 0.3 1.5 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus Biotin_lipoyl_2 PF13533.6 AIN95106.1 - 0.0001 22.1 1.5 0.014 15.2 0.1 2.9 2 1 1 3 3 3 2 Biotin-lipoyl like ATP-grasp_3 PF02655.14 AIN95106.1 - 0.00033 20.7 0.1 0.00059 19.9 0.1 1.5 1 0 0 1 1 1 1 ATP-grasp domain GARS_A PF01071.19 AIN95106.1 - 0.0023 17.7 0.0 0.0048 16.7 0.0 1.5 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain ATPgrasp_ST PF14397.6 AIN95106.1 - 0.0077 15.5 0.0 0.024 13.9 0.0 1.8 2 0 0 2 2 2 1 Sugar-transfer associated ATP-grasp HlyD_3 PF13437.6 AIN95106.1 - 0.014 16.1 1.2 0.2 12.4 0.1 2.8 1 1 1 2 2 2 0 HlyD family secretion protein HlyD_D23 PF16576.5 AIN95106.1 - 0.018 14.3 1.3 0.26 10.5 0.1 2.3 1 1 1 2 2 2 0 Barrel-sandwich domain of CusB or HlyD membrane-fusion RNA_pol_inhib PF16857.5 AIN95106.1 - 0.18 11.7 0.6 1.3 8.8 0.0 2.7 3 0 0 3 3 3 0 RNA polymerase inhibitor PLC-beta_C PF08703.10 AIN95107.1 - 0.0051 16.8 3.4 0.0051 16.8 3.4 1.4 2 0 0 2 2 2 1 PLC-beta C terminal DUF3138 PF11336.8 AIN95107.1 - 0.17 10.5 3.3 0.23 10.1 3.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) Tox-ODYAM1 PF15642.6 AIN95107.1 - 0.27 10.1 4.2 0.37 9.7 4.2 1.1 1 0 0 1 1 1 0 Toxin in Odyssella and Amoebophilus DltD PF04914.12 AIN95107.1 - 1.1 8.6 3.7 1.5 8.2 3.7 1.1 1 0 0 1 1 1 0 DltD protein Atg14 PF10186.9 AIN95107.1 - 1.4 8.0 7.7 1.6 7.7 7.7 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 BSD PF03909.17 AIN95108.1 - 1.7e-07 31.1 0.0 3.2e-07 30.3 0.0 1.4 1 0 0 1 1 1 1 BSD domain Thymidylate_kin PF02223.17 AIN95110.1 - 1.3e-32 113.0 0.0 1.6e-32 112.7 0.0 1.1 1 0 0 1 1 1 1 Thymidylate kinase AAA_33 PF13671.6 AIN95110.1 - 1.9e-05 24.8 0.0 5.7e-05 23.3 0.0 1.8 1 1 1 2 2 2 1 AAA domain AAA_18 PF13238.6 AIN95110.1 - 5.1e-05 23.8 0.0 0.00021 21.8 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 AIN95110.1 - 0.006 17.0 0.1 0.0095 16.3 0.1 1.4 1 1 0 1 1 1 1 AAA ATPase domain AAA PF00004.29 AIN95110.1 - 0.014 15.8 0.0 0.039 14.4 0.0 1.8 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) TsaE PF02367.17 AIN95110.1 - 0.015 15.3 0.0 0.056 13.4 0.0 1.9 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_28 PF13521.6 AIN95110.1 - 0.026 14.7 0.4 0.049 13.9 0.4 1.5 1 1 0 1 1 1 0 AAA domain 6PF2K PF01591.18 AIN95110.1 - 0.028 13.7 0.0 0.041 13.2 0.0 1.2 1 0 0 1 1 1 0 6-phosphofructo-2-kinase AAA_22 PF13401.6 AIN95110.1 - 0.028 14.7 0.0 0.067 13.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain Glyco_transf_28 PF03033.20 AIN95110.1 - 0.03 14.4 0.0 0.063 13.3 0.0 1.5 1 0 0 1 1 1 0 Glycosyltransferase family 28 N-terminal domain Vps39_2 PF10367.9 AIN95110.1 - 0.043 14.3 0.3 1.5 9.3 0.0 3.1 4 1 0 4 4 4 0 Vacuolar sorting protein 39 domain 2 AAA_19 PF13245.6 AIN95110.1 - 0.062 13.6 0.1 0.11 12.8 0.1 1.7 1 1 0 1 1 1 0 AAA domain DUF853 PF05872.12 AIN95110.1 - 0.068 11.8 0.0 0.1 11.2 0.0 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) AAA_30 PF13604.6 AIN95110.1 - 0.077 12.7 0.1 0.22 11.2 0.0 1.9 2 1 0 2 2 2 0 AAA domain DUF2075 PF09848.9 AIN95110.1 - 0.08 12.2 0.1 0.16 11.2 0.0 1.5 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) Glyco_transf_11 PF01531.16 AIN95111.1 - 7.2e-11 41.8 0.1 5.2e-08 32.5 0.0 2.1 2 0 0 2 2 2 2 Glycosyl transferase family 11 Glutaredoxin PF00462.24 AIN95112.1 - 9.6e-18 64.2 0.3 1.7e-17 63.4 0.1 1.5 2 0 0 2 2 2 1 Glutaredoxin ATG16 PF08614.11 AIN95113.1 - 0.55 10.4 5.0 1.2 9.4 0.1 2.7 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) Par3_HAL_N_term PF12053.8 AIN95115.1 - 0.038 14.2 0.0 0.064 13.5 0.0 1.4 1 1 0 1 1 1 0 N-terminal of Par3 and HAL proteins LSM PF01423.22 AIN95117.1 - 2.8e-10 39.7 0.0 3.2e-10 39.5 0.0 1.1 1 0 0 1 1 1 1 LSM domain Voltage_CLC PF00654.20 AIN95119.1 - 4.4e-90 302.5 31.6 5.4e-89 298.9 29.3 2.0 2 0 0 2 2 2 2 Voltage gated chloride channel CBS PF00571.28 AIN95119.1 - 0.00021 21.7 0.0 0.07 13.6 0.0 2.6 2 0 0 2 2 2 2 CBS domain DLEU7 PF15760.5 AIN95120.1 - 0.11 11.9 0.3 0.11 11.9 0.3 1.9 2 0 0 2 2 2 0 Leukemia-associated protein 7 LMWPc PF01451.21 AIN95121.1 - 9.1e-06 26.1 0.0 1.6e-05 25.4 0.0 1.4 1 0 0 1 1 1 1 Low molecular weight phosphotyrosine protein phosphatase CUE PF02845.16 AIN95122.1 - 2.5e-15 55.8 0.1 1.1e-06 28.2 0.0 4.0 4 0 0 4 4 4 3 CUE domain Smr PF01713.21 AIN95122.1 - 2.4e-10 40.6 0.7 7e-10 39.1 0.7 1.9 1 0 0 1 1 1 1 Smr domain DUF1771 PF08590.10 AIN95122.1 - 1.3e-08 35.1 0.1 6e-08 33.0 0.1 2.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1771) UBA PF00627.31 AIN95122.1 - 3.9e-06 26.6 0.0 0.017 15.0 0.0 2.9 2 0 0 2 2 2 2 UBA/TS-N domain DMA PF03474.14 AIN95122.1 - 0.012 15.1 0.0 6.5 6.4 0.0 2.6 2 0 0 2 2 2 0 DMRTA motif zf_CCCH_4 PF18345.1 AIN95122.1 - 4 7.6 30.3 0.26 11.4 0.2 4.9 4 1 0 4 4 4 0 Zinc finger domain Pro_isomerase PF00160.21 AIN95123.1 - 1.5e-37 129.3 0.0 2.1e-37 128.8 0.0 1.2 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD SNF2_N PF00176.23 AIN95125.1 - 8.6e-39 133.2 0.0 1.5e-38 132.4 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 AIN95125.1 - 8.2e-15 55.1 0.0 2e-14 53.9 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 AIN95125.1 - 2e-05 24.5 0.0 3.7e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 AIN95125.1 - 0.00025 21.1 0.0 0.001 19.1 0.0 2.0 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit SWI2_SNF2 PF18766.1 AIN95125.1 - 0.15 11.7 0.1 0.56 9.8 0.1 1.9 1 1 0 1 1 1 0 SWI2/SNF2 ATPase Beta_helix PF13229.6 AIN95126.1 - 7.1e-11 42.2 0.1 1.3e-10 41.4 0.1 1.3 1 0 0 1 1 1 1 Right handed beta helix region NosD PF05048.13 AIN95126.1 - 1.7e-06 27.5 0.1 2.7e-06 26.8 0.1 1.2 1 0 0 1 1 1 1 Periplasmic copper-binding protein (NosD) TetR_C_31 PF17940.1 AIN95126.1 - 0.39 11.0 5.7 1 9.6 1.4 2.8 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain Enkurin PF13864.6 AIN95127.1 - 6.6e-20 71.4 7.3 6.6e-20 71.4 7.3 1.7 2 0 0 2 2 2 1 Calmodulin-binding Med3 PF11593.8 AIN95127.1 - 0.48 9.6 4.1 0.52 9.4 2.8 1.6 1 1 0 1 1 1 0 Mediator complex subunit 3 fungal POP1 PF06978.11 AIN95127.1 - 0.83 9.6 6.3 0.26 11.2 2.8 1.7 2 0 0 2 2 2 0 Ribonucleases P/MRP protein subunit POP1 Thioredoxin PF00085.20 AIN95128.1 - 2.1e-20 72.6 0.1 2.5e-20 72.4 0.1 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 AIN95128.1 - 0.00059 20.1 0.2 0.024 14.9 0.1 2.1 1 1 1 2 2 2 2 Thioredoxin-like Thioredoxin_2 PF13098.6 AIN95128.1 - 0.0006 20.2 0.3 0.0029 18.0 0.3 1.9 1 1 0 1 1 1 1 Thioredoxin-like domain OST3_OST6 PF04756.13 AIN95128.1 - 0.0045 16.4 0.0 0.0048 16.3 0.0 1.1 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family AhpC-TSA PF00578.21 AIN95128.1 - 0.0077 16.1 0.0 0.0087 16.0 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_6 PF13848.6 AIN95128.1 - 0.037 13.9 0.0 0.043 13.7 0.0 1.1 1 0 0 1 1 1 0 Thioredoxin-like domain Phosducin PF02114.16 AIN95128.1 - 0.039 12.9 0.0 0.042 12.8 0.0 1.1 1 0 0 1 1 1 0 Phosducin HyaE PF07449.11 AIN95128.1 - 0.059 13.3 0.0 0.089 12.8 0.0 1.2 1 0 0 1 1 1 0 Hydrogenase-1 expression protein HyaE Thioredoxin_7 PF13899.6 AIN95128.1 - 0.06 13.5 0.3 0.095 12.9 0.3 1.5 1 1 0 1 1 1 0 Thioredoxin-like PseudoU_synth_2 PF00849.22 AIN95129.1 - 3.8e-22 79.1 0.0 1.4e-21 77.2 0.0 1.8 2 0 0 2 2 2 1 RNA pseudouridylate synthase Cmc1 PF08583.10 AIN95130.1 - 4.3e-06 26.7 3.3 7.1e-06 25.9 3.3 1.3 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like CX9C PF16860.5 AIN95130.1 - 0.0036 17.3 4.5 0.0076 16.2 4.5 1.5 1 0 0 1 1 1 1 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, CHCH PF06747.13 AIN95130.1 - 0.049 13.8 3.2 1.7 8.9 3.2 2.4 1 1 1 2 2 2 0 CHCH domain COX17 PF05051.13 AIN95130.1 - 0.09 13.1 2.0 0.095 13.1 0.2 1.9 2 0 0 2 2 2 0 Cytochrome C oxidase copper chaperone (COX17) UCR_hinge PF02320.16 AIN95130.1 - 0.46 10.7 5.7 1.9 8.8 0.5 2.5 1 1 1 2 2 2 0 Ubiquinol-cytochrome C reductase hinge protein 4F5 PF04419.14 AIN95131.1 - 8.1e-13 49.0 7.2 8.1e-13 49.0 7.2 2.0 1 1 1 2 2 2 1 4F5 protein family DHHA2 PF02833.14 AIN95132.1 - 1e-22 80.9 0.0 3.9e-22 79.0 0.0 1.8 2 0 0 2 2 2 1 DHHA2 domain DHH PF01368.20 AIN95132.1 - 1.4e-08 34.8 0.0 2.5e-08 34.1 0.0 1.4 1 0 0 1 1 1 1 DHH family Thoc2 PF11732.8 AIN95132.1 - 0.1 12.7 0.1 0.41 10.7 0.0 2.1 2 1 0 2 2 2 0 Transcription- and export-related complex subunit Dor1 PF04124.12 AIN95133.1 - 0.1 11.2 0.0 0.14 10.9 0.0 1.1 1 0 0 1 1 1 0 Dor1-like family WD40 PF00400.32 AIN95134.1 - 0.001 19.9 2.6 0.034 15.0 0.2 3.1 3 0 0 3 3 3 1 WD domain, G-beta repeat PQQ_2 PF13360.6 AIN95134.1 - 0.056 13.0 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 PQQ-like domain ANAPC4_WD40 PF12894.7 AIN95134.1 - 0.15 12.4 0.0 19 5.7 0.0 3.3 2 1 1 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain Urate_ox_N PF06181.11 AIN95135.1 - 0.017 14.5 0.1 0.02 14.3 0.1 1.1 1 0 0 1 1 1 0 Urate oxidase N-terminal MPC PF03650.13 AIN95136.1 - 1.1e-16 60.9 0.6 1.3e-16 60.7 0.6 1.1 1 0 0 1 1 1 1 Mitochondrial pyruvate carriers Rpn3_C PF08375.11 AIN95138.1 - 0.022 15.2 1.6 0.053 13.9 1.6 1.7 1 0 0 1 1 1 0 Proteasome regulatory subunit C-terminal Aldedh PF00171.22 AIN95138.1 - 0.092 11.2 2.2 0.15 10.6 2.2 1.2 1 0 0 1 1 1 0 Aldehyde dehydrogenase family ApoLp-III PF07464.11 AIN95138.1 - 0.16 12.1 1.6 0.32 11.1 1.6 1.4 1 0 0 1 1 1 0 Apolipophorin-III precursor (apoLp-III) FlgN PF05130.12 AIN95138.1 - 1.3 9.5 12.6 1.4 9.4 4.1 2.7 2 1 1 3 3 3 0 FlgN protein TACC_C PF05010.14 AIN95138.1 - 1.4 8.6 10.1 2.5 7.9 10.1 1.3 1 0 0 1 1 1 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal NEMO PF11577.8 AIN95138.1 - 1.4 8.9 7.5 0.38 10.8 3.7 2.0 2 0 0 2 2 2 0 NF-kappa-B essential modulator NEMO DUF1451 PF07295.11 AIN95138.1 - 1.7 8.7 8.6 1.1 9.3 3.2 2.3 1 1 1 2 2 2 0 Zinc-ribbon containing domain TMEM208_SND2 PF05620.11 AIN95140.1 - 1.1e-34 119.7 0.0 1.2e-34 119.5 0.0 1.0 1 0 0 1 1 1 1 SRP-independent targeting protein 2/TMEM208 Dymeclin PF09742.9 AIN95141.1 - 7e-48 163.5 0.0 8.4e-48 163.2 0.0 1.0 1 0 0 1 1 1 1 Dyggve-Melchior-Clausen syndrome protein FSA_C PF10479.9 AIN95141.1 - 0.057 11.6 0.5 0.14 10.2 0.5 1.6 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus Hid1 PF12722.7 AIN95141.1 - 1.6 6.8 4.9 9 4.3 0.3 2.6 3 0 0 3 3 3 0 High-temperature-induced dauer-formation protein Dehydrin PF00257.19 AIN95142.1 - 0.069 13.7 0.3 0.069 13.7 0.3 2.3 3 0 0 3 3 3 0 Dehydrin DUF1664 PF07889.12 AIN95142.1 - 0.31 11.1 3.6 0.24 11.5 0.6 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) IMUP PF15761.5 AIN95142.1 - 7.4 7.3 9.2 10 6.9 5.4 2.5 2 0 0 2 2 2 0 Immortalisation up-regulated protein Ribosomal_S7e PF01251.18 AIN95144.1 - 2.9e-63 213.0 3.0 3.3e-63 212.8 3.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S7e zf-UBP PF02148.19 AIN95145.1 - 1.1e-10 41.6 8.6 1.1e-10 41.6 8.6 2.4 2 0 0 2 2 1 1 Zn-finger in ubiquitin-hydrolases and other protein zf-RING_2 PF13639.6 AIN95145.1 - 3.4e-08 33.7 7.9 3.4e-08 33.7 7.9 3.0 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.6 AIN95145.1 - 2.5e-06 27.2 9.6 2.5e-06 27.2 9.6 2.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 AIN95145.1 - 0.00013 21.7 16.3 0.0014 18.4 3.6 2.6 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 AIN95145.1 - 0.00031 21.0 4.6 0.00031 21.0 4.6 2.6 2 0 0 2 2 1 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 AIN95145.1 - 0.0017 18.3 6.7 0.0017 18.3 6.7 3.0 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4 PF00097.25 AIN95145.1 - 0.0042 16.9 8.4 0.0042 16.9 8.4 3.3 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 AIN95145.1 - 0.0067 16.2 5.5 0.0067 16.2 5.5 3.0 4 0 0 4 4 4 1 RING-like zinc finger zf-RING_UBOX PF13445.6 AIN95145.1 - 0.018 15.1 5.8 0.018 15.1 5.8 2.9 1 1 1 2 2 2 0 RING-type zinc-finger MeaB PF03308.16 AIN95145.1 - 0.031 13.3 1.3 0.07 12.1 1.3 1.6 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB zf-ANAPC11 PF12861.7 AIN95145.1 - 0.034 14.2 3.8 0.11 12.5 3.8 1.9 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Seryl_tRNA_N PF02403.22 AIN95145.1 - 0.051 13.8 6.6 0.099 12.9 6.6 1.4 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain RecR PF02132.15 AIN95145.1 - 0.2 11.3 10.5 0.13 11.8 0.7 3.2 3 0 0 3 3 3 0 RecR protein zf-C3HC4_4 PF15227.6 AIN95145.1 - 0.89 9.8 21.5 2.2 8.5 11.5 2.6 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING Caskin-Pro-rich PF16907.5 AIN95145.1 - 9.4 6.8 10.6 1.9 9.1 4.1 3.0 3 1 0 3 3 2 0 Proline rich region of Caskin proteins Zn_ribbon_17 PF17120.5 AIN95145.1 - 9.6 5.9 16.5 0.74 9.5 3.9 2.8 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type MFS_5 PF05631.14 AIN95146.1 - 2.5e-10 39.8 4.2 5.5e-06 25.5 0.6 2.4 2 0 0 2 2 2 2 Sugar-tranasporters, 12 TM Isochorismatase PF00857.20 AIN95147.1 - 2.1e-22 80.1 0.0 2.6e-22 79.9 0.0 1.1 1 0 0 1 1 1 1 Isochorismatase family AAA_16 PF13191.6 AIN95148.1 - 2.2e-05 24.9 0.0 6.1e-05 23.5 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain AAA_18 PF13238.6 AIN95148.1 - 3.2e-05 24.5 0.0 7.4e-05 23.3 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.6 AIN95148.1 - 0.004 17.6 0.0 0.0078 16.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain Paired_CXXCH_1 PF09699.10 AIN95148.1 - 0.016 14.9 1.3 0.05 13.4 1.3 1.8 1 0 0 1 1 1 0 Doubled CXXCH motif (Paired_CXXCH_1) PAM2 PF07145.15 AIN95148.1 - 0.025 14.2 0.1 0.069 12.9 0.1 1.7 1 0 0 1 1 1 0 Ataxin-2 C-terminal region AAA_28 PF13521.6 AIN95148.1 - 0.032 14.5 0.0 0.064 13.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 AIN95148.1 - 0.05 14.0 0.0 0.091 13.2 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) NB-ARC PF00931.22 AIN95148.1 - 0.15 11.2 0.0 0.25 10.5 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain KTI12 PF08433.10 AIN95148.1 - 0.24 10.8 0.0 0.46 9.9 0.0 1.4 1 0 0 1 1 1 0 Chromatin associated protein KTI12 AMP-binding PF00501.28 AIN95149.1 - 4.1e-87 292.5 0.1 5.3e-87 292.1 0.1 1.1 1 0 0 1 1 1 1 AMP-binding enzyme Beta_elim_lyase PF01212.21 AIN95150.1 - 2.7e-32 112.2 0.0 3.3e-32 112.0 0.0 1.1 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.19 AIN95150.1 - 1.6e-08 34.0 0.0 2.2e-08 33.4 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.21 AIN95150.1 - 1.5e-07 30.9 0.0 2.2e-07 30.4 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II Pyridoxal_deC PF00282.19 AIN95150.1 - 0.027 13.2 0.0 0.049 12.3 0.0 1.3 1 0 0 1 1 1 0 Pyridoxal-dependent decarboxylase conserved domain AMP-binding PF00501.28 AIN95151.1 - 9e-94 314.4 0.0 1.2e-93 314.0 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding PF00501.28 AIN95152.1 - 4.1e-95 318.9 0.0 5.6e-95 318.4 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme DUF4476 PF14771.6 AIN95152.1 - 0.001 19.3 0.1 0.0022 18.3 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4476) AMP-binding PF00501.28 AIN95153.1 - 2.9e-47 161.2 0.1 3.6e-34 118.1 0.0 2.7 2 1 0 2 2 2 2 AMP-binding enzyme zf-CCHC_3 PF13917.6 AIN95155.1 - 4.5e-07 29.7 14.1 0.0053 16.7 0.4 3.6 3 0 0 3 3 3 2 Zinc knuckle P_C PF06640.11 AIN95155.1 - 0.0083 16.3 1.4 0.0083 16.3 1.4 3.6 2 1 0 3 3 3 1 P protein C-terminus DUF5637 PF18687.1 AIN95155.1 - 0.058 13.4 8.6 1.5 8.9 0.7 2.7 2 0 0 2 2 2 0 Family of unknown function (DUF5637) FOXP-CC PF16159.5 AIN95155.1 - 0.15 12.7 3.9 7.1 7.3 0.4 2.8 2 0 0 2 2 2 0 FOXP coiled-coil domain zf-CCHC PF00098.23 AIN95155.1 - 1.2 9.3 31.7 0.17 12.0 2.4 3.4 3 0 0 3 3 3 0 Zinc knuckle zinc-ribbons_6 PF07191.12 AIN95155.1 - 1.8 8.6 17.9 7.8 6.6 1.2 3.3 3 0 0 3 3 3 0 zinc-ribbons PRP3 PF08572.10 AIN95156.1 - 5.6e-13 49.2 1.4 2.9e-12 46.8 1.4 2.0 1 1 0 1 1 1 1 pre-mRNA processing factor 3 (PRP3) DUF1115 PF06544.12 AIN95156.1 - 5e-12 46.1 0.0 1.1e-11 45.1 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF1115) Mtc PF03820.17 AIN95157.1 - 2.4e-84 283.1 0.6 2.6e-84 282.9 0.6 1.0 1 0 0 1 1 1 1 Tricarboxylate carrier RNA_ligase PF09414.10 AIN95159.1 - 7.1e-21 75.2 0.0 1e-20 74.7 0.0 1.3 1 0 0 1 1 1 1 RNA ligase T4_Rnl2_C PF18043.1 AIN95159.1 - 3.9e-07 30.1 0.1 7.6e-07 29.2 0.1 1.4 1 0 0 1 1 1 1 T4 RNA ligase 2 C-terminal PdxA PF04166.12 AIN95159.1 - 0.032 13.7 0.0 0.05 13.0 0.0 1.2 1 0 0 1 1 1 0 Pyridoxal phosphate biosynthetic protein PdxA RabGAP-TBC PF00566.18 AIN95160.1 - 1.4e-24 87.0 0.0 1.4e-11 44.5 0.3 2.3 2 0 0 2 2 2 2 Rab-GTPase-TBC domain Asp_protease PF09668.10 AIN95161.1 - 6.9e-57 190.6 0.6 1e-56 190.0 0.6 1.3 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 AIN95161.1 - 2.1e-17 63.5 0.0 5.8e-17 62.0 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 AIN95161.1 - 2.4e-07 31.3 0.0 7.2e-07 29.8 0.0 1.9 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 AIN95161.1 - 6.7e-05 22.7 0.0 0.00014 21.7 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease UBA_4 PF14555.6 AIN95161.1 - 0.00017 21.4 0.2 0.0003 20.5 0.2 1.4 1 0 0 1 1 1 1 UBA-like domain RVP PF00077.20 AIN95161.1 - 0.025 14.9 0.0 0.063 13.6 0.0 1.7 1 0 0 1 1 1 0 Retroviral aspartyl protease EF-hand_8 PF13833.6 AIN95162.1 - 0.022 14.6 0.0 0.041 13.7 0.0 1.5 1 0 0 1 1 1 0 EF-hand domain pair EF-hand_1 PF00036.32 AIN95162.1 - 0.1 12.2 0.0 0.2 11.3 0.0 1.5 1 0 0 1 1 1 0 EF hand HSP70 PF00012.20 AIN95164.1 - 1.6e-27 96.0 1.7 5.1e-24 84.4 0.1 4.0 3 1 0 3 3 3 2 Hsp70 protein MreB_Mbl PF06723.13 AIN95164.1 - 0.014 14.2 0.7 0.027 13.3 0.7 1.3 1 0 0 1 1 1 0 MreB/Mbl protein Peptidase_M16 PF00675.20 AIN95165.1 - 1.1e-39 135.8 0.1 3.8e-39 134.0 0.0 1.8 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 AIN95165.1 - 1.9e-16 60.6 0.0 1.9e-14 54.1 0.0 3.4 3 1 0 3 3 3 1 Peptidase M16 inactive domain DUF4795 PF16043.5 AIN95165.1 - 0.17 11.4 0.0 0.35 10.4 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4795) ORC2 PF04084.14 AIN95166.1 - 2.6e-07 29.9 0.0 0.0018 17.3 0.0 2.3 2 0 0 2 2 2 2 Origin recognition complex subunit 2 FANCA_interact PF15751.5 AIN95167.1 - 0.63 10.5 6.2 1 9.9 0.1 2.9 2 1 1 3 3 3 0 FAAP20 FANCA interaction domain PLAC8 PF04749.17 AIN95169.1 - 2e-13 51.1 8.6 3e-13 50.6 8.6 1.3 1 0 0 1 1 1 1 PLAC8 family Alpha_GJ PF03229.13 AIN95169.1 - 0.73 10.4 4.0 2 9.0 0.3 2.2 1 1 1 2 2 2 0 Alphavirus glycoprotein J PLAC8 PF04749.17 AIN95170.1 - 1.8e-13 51.3 8.6 2.9e-13 50.7 8.6 1.3 1 0 0 1 1 1 1 PLAC8 family zf-RING_14 PF17978.1 AIN95170.1 - 1.8 9.0 7.5 0.28 11.6 3.6 1.6 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain ThiF PF00899.21 AIN95171.1 - 2.3e-75 253.1 0.0 5.6e-75 251.9 0.0 1.6 1 1 0 1 1 1 1 ThiF family DASH_Spc19 PF08287.11 AIN95173.1 - 0.62 9.9 3.1 1.2 9.0 3.1 1.4 1 0 0 1 1 1 0 Spc19 DEAD PF00270.29 AIN95175.1 - 2e-42 144.9 0.1 5.6e-42 143.5 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 AIN95175.1 - 5.5e-29 100.7 0.3 3.2e-28 98.3 0.1 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain CMS1 PF14617.6 AIN95175.1 - 5.5e-05 22.6 0.2 0.00017 21.0 0.0 1.8 2 0 0 2 2 2 1 U3-containing 90S pre-ribosomal complex subunit AAA_22 PF13401.6 AIN95175.1 - 0.065 13.5 0.7 0.33 11.2 0.7 2.3 1 1 0 1 1 1 0 AAA domain DGF-1_C PF11040.8 AIN95176.1 - 1.4 8.9 4.8 23 5.1 4.7 2.9 1 1 0 1 1 1 0 Dispersed gene family protein 1 of Trypanosoma cruzi C-terminus zf-C2H2 PF00096.26 AIN95177.1 - 0.0021 18.4 1.8 0.0072 16.7 1.8 2.0 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 AIN95177.1 - 0.013 16.3 1.5 0.032 15.1 1.5 1.7 1 0 0 1 1 1 0 C2H2-type zinc finger CpXC PF14353.6 AIN95177.1 - 0.041 13.9 0.2 0.068 13.2 0.2 1.3 1 0 0 1 1 1 0 CpXC protein FYDLN_acid PF09538.10 AIN95177.1 - 0.11 13.2 2.0 0.23 12.1 2.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (FYDLN_acid) zf-C2H2_6 PF13912.6 AIN95177.1 - 0.18 11.8 0.3 0.33 11.0 0.3 1.4 1 0 0 1 1 1 0 C2H2-type zinc finger BK_channel_a PF03493.18 AIN95178.1 - 3.9e-12 46.2 0.0 1.1e-11 44.8 0.0 1.7 2 0 0 2 2 2 1 Calcium-activated BK potassium channel alpha subunit Ion_trans_2 PF07885.16 AIN95178.1 - 1.8e-10 40.6 4.6 7.5e-10 38.6 4.6 2.1 1 0 0 1 1 1 1 Ion channel Ion_trans_2 PF07885.16 AIN95179.1 - 2.1e-11 43.6 5.4 7.5e-11 41.8 5.4 1.9 1 0 0 1 1 1 1 Ion channel BK_channel_a PF03493.18 AIN95179.1 - 2.3e-06 27.7 0.0 6.4e-06 26.3 0.0 1.7 1 0 0 1 1 1 1 Calcium-activated BK potassium channel alpha subunit Tubulin_C PF03953.17 AIN95180.1 - 3e-12 46.8 0.1 4.4e-12 46.3 0.1 1.2 1 0 0 1 1 1 1 Tubulin C-terminal domain Cyt-b5 PF00173.28 AIN95181.1 - 9.7e-43 144.2 0.2 1.3e-20 73.3 0.0 2.1 2 0 0 2 2 2 2 Cytochrome b5-like Heme/Steroid binding domain EFP_N PF08207.12 AIN95181.1 - 0.017 15.1 0.0 2.3 8.3 0.0 2.4 2 0 0 2 2 2 0 Elongation factor P (EF-P) KOW-like domain SPT_ssu-like PF11779.8 AIN95181.1 - 0.053 13.2 0.0 0.094 12.4 0.0 1.4 1 0 0 1 1 1 0 Small subunit of serine palmitoyltransferase-like PAC4 PF16093.5 AIN95182.1 - 0.052 13.7 0.0 0.087 13.0 0.0 1.4 1 0 0 1 1 1 0 Proteasome assembly chaperone 4 SRP14 PF02290.15 AIN95186.1 - 0.31 11.4 1.3 1.1 9.7 0.1 2.4 3 0 0 3 3 3 0 Signal recognition particle 14kD protein TPPII_N PF12583.8 AIN95186.1 - 6 7.4 9.9 6.2 7.4 3.8 2.6 2 0 0 2 2 2 0 Tripeptidyl peptidase II N terminal Torus PF16131.5 AIN95187.1 - 0.005 17.5 2.2 1.7 9.4 0.1 2.6 2 0 0 2 2 2 2 Torus domain Xpo1 PF08389.12 AIN95188.1 - 9.9e-25 87.3 2.3 8.2e-23 81.1 0.1 3.6 3 0 0 3 3 3 1 Exportin 1-like protein CNOT11 PF10155.9 AIN95188.1 - 0.019 15.1 0.1 0.12 12.6 0.1 2.4 1 0 0 1 1 1 0 CCR4-NOT transcription complex subunit 11 RdgC PF04381.12 AIN95188.1 - 0.14 11.4 0.7 1.9 7.7 0.1 2.4 2 0 0 2 2 2 0 Putative exonuclease, RdgC UME PF08064.13 AIN95188.1 - 1.7 8.6 4.9 5.3 7.0 0.1 3.5 3 0 0 3 3 3 0 UME (NUC010) domain PI3_PI4_kinase PF00454.27 AIN95189.1 - 1.9e-42 145.8 0.0 3e-42 145.2 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FATC PF02260.20 AIN95189.1 - 3.3e-08 33.2 1.1 6e-08 32.4 0.1 2.1 2 0 0 2 2 2 1 FATC domain SF3A2 PF16835.5 AIN95190.1 - 2.3e-22 79.2 0.0 3.5e-22 78.6 0.0 1.3 1 0 0 1 1 1 1 Pre-mRNA-splicing factor SF3a complex subunit 2 (Prp11) zf-met PF12874.7 AIN95190.1 - 0.00063 20.0 0.2 0.0015 18.9 0.2 1.7 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 AIN95190.1 - 0.0042 17.3 0.2 0.0085 16.4 0.2 1.5 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding AAA_25 PF13481.6 AIN95190.1 - 0.068 12.7 0.2 0.14 11.7 0.1 1.5 1 1 0 1 1 1 0 AAA domain Ank_2 PF12796.7 AIN95191.1 - 1.4e-11 44.9 0.2 2.6e-10 40.8 0.1 2.4 1 1 1 2 2 2 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 AIN95191.1 - 6e-09 36.3 0.1 2.7e-05 24.6 0.1 3.4 1 1 2 3 3 3 2 Ankyrin repeats (many copies) zf-C3HC4_3 PF13920.6 AIN95191.1 - 4.2e-07 29.7 11.3 9.2e-07 28.6 11.3 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Ank_5 PF13857.6 AIN95191.1 - 0.00039 20.7 0.1 0.0058 16.9 0.1 2.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 AIN95191.1 - 0.0011 19.3 0.2 0.013 16.0 0.0 2.8 3 0 0 3 3 3 1 Ankyrin repeat zf-RING_2 PF13639.6 AIN95191.1 - 0.0037 17.6 13.5 0.011 16.1 13.5 1.9 1 0 0 1 1 1 1 Ring finger domain Ank PF00023.30 AIN95191.1 - 0.0045 17.4 1.1 0.033 14.6 0.1 2.8 3 0 0 3 3 3 1 Ankyrin repeat zf-C3HC4_4 PF15227.6 AIN95191.1 - 2.3 8.4 10.8 11 6.3 10.8 2.3 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING Vps51 PF08700.11 AIN95193.1 - 9.8e-10 38.4 0.0 2.5e-09 37.1 0.0 1.6 1 0 0 1 1 1 1 Vps51/Vps67 Clathrin_H_link PF13838.6 AIN95193.1 - 0.21 11.5 0.8 0.91 9.5 0.1 2.4 2 0 0 2 2 2 0 Clathrin-H-link Galactosyl_T PF01762.21 AIN95194.1 - 0.0045 16.8 0.3 0.13 12.1 0.1 3.0 3 0 0 3 3 3 1 Galactosyltransferase Galactosyl_T PF01762.21 AIN95195.1 - 0.0021 17.9 0.0 0.0061 16.4 0.0 1.8 1 1 0 1 1 1 1 Galactosyltransferase GlcNAc PF11397.8 AIN95196.1 - 1.4e-138 462.2 0.0 2.1e-138 461.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase (GlcNAc) GlcNAc PF11397.8 AIN95197.1 - 3.4e-06 26.8 0.1 0.069 12.6 0.0 2.9 2 1 0 2 2 2 2 Glycosyltransferase (GlcNAc) Hexapep_loop PF18776.1 AIN95197.1 - 0.33 10.6 1.3 2.7 7.7 0.2 2.7 3 0 0 3 3 3 0 Hexapeptide repeat including loop Ras PF00071.22 AIN95198.1 - 5.3e-54 182.2 0.1 6.9e-54 181.8 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 AIN95198.1 - 4.8e-38 130.0 0.1 7.2e-38 129.5 0.1 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 AIN95198.1 - 1.7e-16 60.2 0.1 2.1e-16 59.9 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 AIN95198.1 - 3.9e-06 26.4 0.2 5.1e-06 26.0 0.2 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 AIN95198.1 - 0.00016 21.2 0.1 0.00045 19.8 0.1 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 AIN95198.1 - 0.00053 19.5 0.0 0.0009 18.7 0.1 1.4 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit RsgA_GTPase PF03193.16 AIN95198.1 - 0.0015 18.5 0.1 0.14 12.0 0.0 2.2 2 0 0 2 2 2 1 RsgA GTPase MMR_HSR1 PF01926.23 AIN95198.1 - 0.0019 18.2 0.0 0.0069 16.5 0.0 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase TniB PF05621.11 AIN95198.1 - 0.046 13.1 0.0 0.19 11.1 0.0 1.9 2 0 0 2 2 2 0 Bacterial TniB protein PduV-EutP PF10662.9 AIN95198.1 - 0.056 13.2 0.2 4.2 7.1 0.0 2.2 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation FeoB_N PF02421.18 AIN95198.1 - 0.061 12.9 0.0 3.4 7.2 0.1 2.2 2 0 0 2 2 2 0 Ferrous iron transport protein B AAA_7 PF12775.7 AIN95198.1 - 0.12 11.9 0.0 0.22 11.0 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_24 PF13479.6 AIN95198.1 - 0.14 11.9 0.0 0.17 11.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain DLIC PF05783.11 AIN95198.1 - 0.61 8.8 6.7 0.46 9.3 0.1 2.0 1 1 1 2 2 2 0 Dynein light intermediate chain (DLIC) UPF0158 PF03682.13 AIN95199.1 - 0.035 14.1 0.0 0.041 13.9 0.0 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0158) Lectin_C_term PF18022.1 AIN95199.1 - 0.092 13.2 0.2 0.14 12.7 0.2 1.3 1 1 0 1 1 1 0 Ricin-type beta-trefoil lectin C-terminal domain Pkinase PF00069.25 AIN95201.1 - 2.5e-47 161.4 0.0 1.4e-46 159.0 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 AIN95201.1 - 8.3e-31 107.2 0.0 1.1e-30 106.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 AIN95201.1 - 1.6e-09 37.5 0.0 2.8e-09 36.7 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 AIN95201.1 - 7.9e-07 28.2 0.0 1.2e-06 27.6 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 AIN95201.1 - 0.12 11.7 0.0 0.18 11.1 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family ABC2_membrane_3 PF12698.7 AIN95202.1 - 2.3e-61 207.8 36.0 1.2e-40 139.7 14.1 2.9 3 0 0 3 3 3 2 ABC-2 family transporter protein ABC_tran PF00005.27 AIN95202.1 - 2.9e-46 157.4 0.0 5.8e-22 78.7 0.0 2.4 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 AIN95202.1 - 2.3e-11 44.1 5.0 0.0027 17.6 0.0 4.7 4 1 1 5 5 5 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 AIN95202.1 - 3e-08 34.4 0.0 0.0039 17.7 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.6 AIN95202.1 - 1.3e-05 24.8 0.1 0.011 15.5 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain SMC_N PF02463.19 AIN95202.1 - 2.6e-05 23.8 0.0 2 7.8 0.0 3.8 3 1 0 4 4 4 2 RecF/RecN/SMC N terminal domain MukB PF04310.12 AIN95202.1 - 0.00043 20.2 0.6 0.3 10.9 0.0 2.5 2 0 0 2 2 2 2 MukB N-terminal AAA_30 PF13604.6 AIN95202.1 - 0.0012 18.5 0.0 0.73 9.5 0.0 2.5 2 0 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 AIN95202.1 - 0.0034 17.3 0.0 0.21 11.5 0.0 2.3 2 0 0 2 2 2 1 RsgA GTPase AAA_27 PF13514.6 AIN95202.1 - 0.0041 16.7 0.0 0.85 9.2 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_15 PF13175.6 AIN95202.1 - 0.03 14.0 0.0 5.8 6.5 0.0 2.6 3 0 0 3 3 3 0 AAA ATPase domain RNA_helicase PF00910.22 AIN95202.1 - 0.1 13.0 0.1 26 5.3 0.0 2.7 3 0 0 3 3 3 0 RNA helicase AAA_25 PF13481.6 AIN95202.1 - 0.41 10.2 2.0 15 5.0 0.0 3.3 3 0 0 3 3 3 0 AAA domain SRP54 PF00448.22 AIN95202.1 - 1.2 8.8 2.4 4.7 6.8 0.2 2.2 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain SNAP PF14938.6 AIN95203.1 - 6.8e-11 42.1 12.7 3.3e-09 36.6 4.4 2.8 2 1 1 3 3 3 2 Soluble NSF attachment protein, SNAP DHR-2 PF06920.13 AIN95203.1 - 0.011 14.4 0.0 0.017 13.8 0.0 1.2 1 0 0 1 1 1 0 Dock homology region 2 DUF1500 PF07389.12 AIN95203.1 - 0.043 13.9 0.0 0.091 12.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1500) RNase_PH PF01138.21 AIN95204.1 - 7.5e-17 62.1 0.0 2.6e-16 60.3 0.0 1.8 2 0 0 2 2 2 1 3' exoribonuclease family, domain 1 UAA PF08449.11 AIN95205.1 - 1e-16 61.0 11.5 1e-10 41.3 1.4 3.7 4 0 0 4 4 4 3 UAA transporter family EamA PF00892.20 AIN95205.1 - 1.4e-05 25.3 3.9 1.4e-05 25.3 3.9 3.2 5 0 0 5 5 5 1 EamA-like transporter family PUNUT PF16913.5 AIN95205.1 - 0.048 12.9 5.3 0.054 12.7 2.6 2.2 2 0 0 2 2 2 0 Purine nucleobase transmembrane transport Pkinase PF00069.25 AIN95207.1 - 5.1e-56 190.0 0.0 6.3e-56 189.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 AIN95207.1 - 9.1e-21 74.3 0.0 1.3e-20 73.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 AIN95207.1 - 2.1e-06 27.8 0.2 0.0004 20.4 0.1 2.4 1 1 1 2 2 2 2 Phosphotransferase enzyme family RIO1 PF01163.22 AIN95207.1 - 0.0037 16.9 0.1 0.0061 16.2 0.1 1.2 1 0 0 1 1 1 1 RIO1 family RPN6_N PF18055.1 AIN95208.1 - 8.2e-30 103.6 0.0 3.6e-29 101.5 0.0 2.2 1 0 0 1 1 1 1 26S proteasome regulatory subunit RPN6 N-terminal domain PCI PF01399.27 AIN95208.1 - 9.2e-13 48.6 0.1 2.4e-12 47.3 0.1 1.8 1 0 0 1 1 1 1 PCI domain TPR_19 PF14559.6 AIN95208.1 - 0.027 15.0 12.7 0.66 10.5 0.2 4.5 5 0 0 5 5 5 0 Tetratricopeptide repeat DDRGK PF09756.9 AIN95208.1 - 0.034 13.7 0.2 0.034 13.7 0.2 2.1 2 0 0 2 2 2 0 DDRGK domain DUF885 PF05960.11 AIN95208.1 - 0.29 10.7 4.6 0.5 9.9 4.6 1.7 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF885) TPR_20 PF14561.6 AIN95208.1 - 1.4 9.3 13.1 2.6 8.5 0.0 4.8 4 1 1 5 5 5 0 Tetratricopeptide repeat FtsJ PF01728.19 AIN95209.1 - 4.2e-64 215.9 0.0 5.5e-64 215.5 0.0 1.2 1 0 0 1 1 1 1 FtsJ-like methyltransferase Ndc1_Nup PF09531.10 AIN95209.1 - 0.22 10.2 0.1 0.33 9.6 0.1 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup UQ_con PF00179.26 AIN95210.1 - 8.1e-41 139.0 0.0 1.6e-40 138.0 0.0 1.4 2 0 0 2 2 2 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 AIN95210.1 - 0.00054 19.7 0.0 0.00076 19.2 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic E2 family B Zn-ribbon_8 PF09723.10 AIN95211.1 - 0.39 10.9 2.1 2.1 8.5 0.3 2.7 3 0 0 3 3 3 0 Zinc ribbon domain zf-C2H2_4 PF13894.6 AIN95211.1 - 7.5 7.7 7.9 3.5 8.7 0.9 3.2 3 0 0 3 3 3 0 C2H2-type zinc finger Stevor PF17410.2 AIN95212.1 - 0.57 9.7 0.0 0.57 9.7 0.0 1.8 2 0 0 2 2 2 0 Subtelomeric Variable Open Reading frame Rhomboid PF01694.22 AIN95213.1 - 1.1e-09 38.4 8.2 4.8e-05 23.4 2.6 2.7 2 1 0 2 2 2 2 Rhomboid family Porin_3 PF01459.22 AIN95214.1 - 6.3e-06 25.8 0.0 0.00034 20.2 0.0 2.1 2 0 0 2 2 2 2 Eukaryotic porin DUF2890 PF11081.8 AIN95215.1 - 0.00011 22.3 0.7 0.00011 22.3 0.7 4.6 3 0 0 3 3 3 2 Protein of unknown function (DUF2890) SLX9 PF15341.6 AIN95216.1 - 0.0062 16.9 9.7 0.058 13.8 9.7 2.5 1 1 0 1 1 1 1 Ribosome biogenesis protein SLX9 SRP-alpha_N PF04086.13 AIN95216.1 - 7.5 6.4 9.5 10 5.9 9.5 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Gly_kinase PF02595.15 AIN95218.1 - 1.9e-37 129.2 12.7 2.5e-18 66.3 2.5 6.7 6 1 0 6 6 6 5 Glycerate kinase family FGE-sulfatase PF03781.16 AIN95219.1 - 0.0089 15.6 0.5 0.012 15.3 0.5 1.2 1 0 0 1 1 1 1 Sulfatase-modifying factor enzyme 1 CDP-OH_P_transf PF01066.21 AIN95222.1 - 0.014 16.2 0.2 0.014 16.2 0.2 2.3 2 1 0 2 2 2 0 CDP-alcohol phosphatidyltransferase Pkinase PF00069.25 AIN95225.1 - 9.6e-57 192.3 0.0 6.5e-51 173.2 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 AIN95225.1 - 3.1e-35 121.7 0.0 4.2e-30 104.9 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 AIN95225.1 - 0.00019 20.9 0.0 0.00088 18.7 0.0 1.9 2 0 0 2 2 2 1 Kinase-like RIO1 PF01163.22 AIN95225.1 - 0.0006 19.5 0.1 0.0015 18.2 0.0 1.6 2 0 0 2 2 2 1 RIO1 family APH PF01636.23 AIN95225.1 - 0.0024 17.8 2.0 0.0025 17.8 0.1 2.0 2 1 0 2 2 2 1 Phosphotransferase enzyme family 7tm_3 PF00003.22 AIN95225.1 - 0.0095 15.7 1.9 0.016 15.0 1.9 1.2 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR Pkinase_fungal PF17667.1 AIN95225.1 - 0.066 12.0 0.0 0.13 11.0 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase FAM176 PF14851.6 AIN95225.1 - 0.082 12.6 0.0 0.24 11.0 0.0 1.8 1 0 0 1 1 1 0 FAM176 family Kdo PF06293.14 AIN95225.1 - 0.1 12.0 0.0 0.19 11.1 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family TraG-D_C PF12696.7 AIN95225.1 - 0.8 9.7 3.5 3 7.8 0.0 2.6 2 0 0 2 2 2 0 TraM recognition site of TraD and TraG ASH PF15780.5 AIN95226.1 - 3.9e-06 27.0 2.8 0.2 11.9 0.0 5.7 5 0 0 5 5 5 2 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin Snf7 PF03357.21 AIN95226.1 - 0.0024 17.5 5.4 0.0045 16.6 5.4 1.4 1 0 0 1 1 1 1 Snf7 TPR_1 PF00515.28 AIN95227.1 - 4.6e-08 32.5 3.4 7.5e-07 28.7 0.7 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.6 AIN95227.1 - 5.6e-06 25.9 1.9 0.00015 21.4 0.3 2.7 2 0 0 2 2 2 1 TPR repeat TPR_2 PF07719.17 AIN95227.1 - 7.1e-06 25.8 0.7 7.1e-06 25.8 0.7 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.6 AIN95227.1 - 5.2e-05 23.1 0.2 0.00017 21.5 0.2 2.0 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_19 PF14559.6 AIN95227.1 - 0.002 18.6 4.4 0.15 12.5 0.5 2.7 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.6 AIN95227.1 - 0.064 14.1 0.4 0.064 14.1 0.4 3.7 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.6 AIN95227.1 - 0.27 11.4 3.1 1.7 8.8 0.3 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat ARPC4 PF05856.12 AIN95228.1 - 5.4e-48 162.8 0.0 6.2e-48 162.6 0.0 1.0 1 0 0 1 1 1 1 ARP2/3 complex 20 kDa subunit (ARPC4) SKA2 PF16740.5 AIN95229.1 - 0.0057 16.4 5.8 0.0057 16.4 5.8 2.5 1 1 1 2 2 2 1 Spindle and kinetochore-associated protein 2 Jnk-SapK_ap_N PF09744.9 AIN95229.1 - 0.0084 16.3 6.0 0.0084 16.3 6.0 2.4 1 1 1 2 2 2 1 JNK_SAPK-associated protein-1 TPR_MLP1_2 PF07926.12 AIN95229.1 - 0.026 14.6 4.6 0.026 14.6 4.6 2.5 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein DUF1776 PF08643.10 AIN95229.1 - 0.1 12.0 0.0 0.19 11.1 0.0 1.4 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) Cauli_DNA-bind PF03310.13 AIN95229.1 - 0.16 12.1 1.0 0.28 11.2 1.0 1.5 1 0 0 1 1 1 0 Caulimovirus DNA-binding protein FlaC_arch PF05377.11 AIN95229.1 - 0.87 10.0 7.9 0.18 12.3 2.0 2.8 2 2 1 3 3 3 0 Flagella accessory protein C (FlaC) Prominin PF05478.11 AIN95229.1 - 2.3 6.1 11.7 9.3 4.1 11.8 1.7 1 1 1 2 2 2 0 Prominin TACC_C PF05010.14 AIN95229.1 - 5 6.9 22.0 6.5 6.5 22.0 1.1 1 0 0 1 1 1 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal Tup_N PF08581.10 AIN95229.1 - 5.7 7.3 16.4 0.9 9.9 8.3 2.6 2 1 0 2 2 2 0 Tup N-terminal TMF_TATA_bd PF12325.8 AIN95229.1 - 6.7 7.0 25.5 0.6 10.3 4.6 3.3 1 1 2 3 3 3 0 TATA element modulatory factor 1 TATA binding WD40 PF00400.32 AIN95230.1 - 0.0056 17.5 1.2 1.2 10.2 1.0 3.7 2 1 0 2 2 2 1 WD domain, G-beta repeat Adeno_E1B_55K PF01696.17 AIN95230.1 - 0.0087 14.8 0.1 0.012 14.3 0.1 1.1 1 0 0 1 1 1 1 Adenovirus EB1 55K protein / large t-antigen Aldedh PF00171.22 AIN95231.1 - 3.7e-06 25.7 1.9 0.0018 16.9 0.0 2.5 2 1 1 3 3 3 2 Aldehyde dehydrogenase family Nop14 PF04147.12 AIN95233.1 - 8.7e-44 150.0 15.9 1.4e-30 106.3 0.2 3.2 2 1 1 3 3 3 3 Nop14-like family Mito_carr PF00153.27 AIN95234.1 - 2.8e-26 91.3 3.7 1.1e-12 47.7 0.2 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein LRR_4 PF12799.7 AIN95235.1 - 4.7e-53 176.3 0.0 0.0011 19.3 0.1 16.2 9 4 9 21 21 21 16 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 AIN95235.1 - 3.8e-06 26.9 0.1 6.8 6.7 0.0 5.9 4 2 0 5 5 5 2 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 AIN95235.1 - 0.00054 19.7 12.2 3.4 7.5 0.0 7.7 8 2 2 10 10 10 2 Leucine rich repeat 2-Hacid_dh_C PF02826.19 AIN95237.1 - 2.4e-54 183.4 0.1 3.6e-54 182.8 0.1 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 AIN95237.1 - 3.6e-35 120.6 0.1 4.8e-35 120.1 0.1 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 AIN95237.1 - 9.5e-06 25.9 0.5 2e-05 24.8 0.5 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase IlvN PF07991.12 AIN95237.1 - 0.0047 16.5 0.2 0.0094 15.5 0.2 1.5 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain AdoHcyase_NAD PF00670.21 AIN95237.1 - 0.015 15.3 0.7 0.03 14.4 0.7 1.4 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain XdhC_C PF13478.6 AIN95237.1 - 0.021 15.3 0.1 0.065 13.7 0.0 1.8 2 0 0 2 2 2 0 XdhC Rossmann domain Aminotran_5 PF00266.19 AIN95238.1 - 1.6e-22 80.0 0.0 2.1e-22 79.6 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-V HHH_5 PF14520.6 AIN95238.1 - 0.1 13.2 0.0 24 5.6 0.0 2.5 2 0 0 2 2 2 0 Helix-hairpin-helix domain Met_10 PF02475.16 AIN95239.1 - 2.1e-41 141.8 0.0 1.1e-37 129.7 0.0 2.1 2 0 0 2 2 2 2 Met-10+ like-protein MTS PF05175.14 AIN95239.1 - 0.00012 21.7 0.0 0.0002 20.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_15 PF09445.10 AIN95239.1 - 0.00038 20.1 0.0 0.00058 19.5 0.0 1.3 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltransf_31 PF13847.6 AIN95239.1 - 0.0061 16.4 0.0 0.046 13.5 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 AIN95239.1 - 0.009 16.7 0.0 0.031 15.0 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain tRNA_U5-meth_tr PF05958.11 AIN95239.1 - 0.083 11.9 0.0 0.14 11.1 0.0 1.2 1 0 0 1 1 1 0 tRNA (Uracil-5-)-methyltransferase MyTH4 PF00784.17 AIN95240.1 - 0.051 14.1 0.0 0.15 12.6 0.0 1.8 1 0 0 1 1 1 0 MyTH4 domain Imm49 PF15575.6 AIN95240.1 - 0.65 9.7 4.6 0.17 11.6 0.2 2.3 3 0 0 3 3 3 0 Immunity protein 49 Acyltransferase PF01553.21 AIN95241.1 - 3.3e-12 46.2 0.0 1.2e-11 44.3 0.0 2.0 1 1 0 1 1 1 1 Acyltransferase zf_UBZ PF18439.1 AIN95241.1 - 0.002 17.7 1.5 0.004 16.7 1.5 1.5 1 0 0 1 1 1 1 Ubiquitin-Binding Zinc Finger ATP-synt_D PF01813.17 AIN95241.1 - 0.023 14.5 0.3 0.048 13.5 0.3 1.4 1 0 0 1 1 1 0 ATP synthase subunit D HopW1-1 PF15457.6 AIN95241.1 - 0.052 12.8 0.0 0.091 12.0 0.0 1.3 1 0 0 1 1 1 0 Type III T3SS secreted effector HopW1-1/HopPmaA PrgI PF12666.7 AIN95241.1 - 0.46 11.2 7.5 2.2 9.1 0.4 2.6 2 0 0 2 2 2 0 PrgI family protein DNA_primase_lrg PF04104.14 AIN95242.1 - 1.7e-81 273.6 0.0 2.2e-81 273.2 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic and archaeal DNA primase, large subunit CtaG_Cox11 PF04442.14 AIN95243.1 - 3.1e-43 147.4 0.1 3.5e-43 147.2 0.1 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein CtaG/Cox11 RNase_H2-Ydr279 PF09468.10 AIN95244.1 - 0.06 13.5 0.8 0.16 12.1 0.8 1.8 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) wHTH domain SHE3 PF17078.5 AIN95244.1 - 7 6.3 11.1 1.4 8.5 0.3 2.7 3 1 0 3 3 3 0 SWI5-dependent HO expression protein 3 YlqD PF11068.8 AIN95244.1 - 9 6.7 13.1 21 5.5 0.1 3.5 3 0 0 3 3 3 0 YlqD protein LRR_4 PF12799.7 AIN95245.1 - 1.6e-10 41.0 14.5 0.0012 19.2 0.4 4.4 3 1 1 4 4 4 4 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 AIN95245.1 - 2.4e-09 36.9 4.4 0.0001 21.8 0.2 2.2 1 1 1 2 2 2 2 Leucine-rich repeat LRR_8 PF13855.6 AIN95245.1 - 6.1e-08 32.3 16.1 0.0014 18.4 1.7 4.0 4 0 0 4 4 4 3 Leucine rich repeat TMF_TATA_bd PF12325.8 AIN95245.1 - 0.0036 17.5 8.9 0.0073 16.5 8.9 1.5 1 0 0 1 1 1 1 TATA element modulatory factor 1 TATA binding DUF4530 PF15039.6 AIN95245.1 - 0.01 16.0 0.1 0.042 14.0 0.1 2.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4530) Dynactin_p62 PF05502.13 AIN95245.1 - 0.021 13.6 0.9 0.034 12.9 0.9 1.2 1 0 0 1 1 1 0 Dynactin p62 family LRR_6 PF13516.6 AIN95245.1 - 0.04 14.0 7.2 1.4 9.1 0.1 4.6 4 1 1 5 5 5 0 Leucine Rich repeat Tup_N PF08581.10 AIN95245.1 - 0.049 13.9 6.6 2.4 8.5 0.8 2.7 2 0 0 2 2 2 0 Tup N-terminal Spc7 PF08317.11 AIN95245.1 - 0.29 10.0 9.3 0.48 9.3 9.3 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein COG2 PF06148.11 AIN95245.1 - 0.3 11.2 3.5 0.42 10.7 2.5 1.7 1 1 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 Filament PF00038.21 AIN95245.1 - 0.87 9.1 13.1 0.43 10.1 10.5 1.8 2 0 0 2 2 2 0 Intermediate filament protein CR6_interact PF10147.9 AIN95245.1 - 1.7 8.3 7.6 1.1 9.0 5.1 1.8 1 1 1 2 2 2 0 Growth arrest and DNA-damage-inducible proteins-interacting protein 1 HALZ PF02183.18 AIN95245.1 - 2.4 8.4 8.9 3.3 8.0 0.5 3.3 3 1 0 3 3 3 0 Homeobox associated leucine zipper ATG16 PF08614.11 AIN95245.1 - 4.7 7.4 16.6 4.8 7.4 8.7 3.0 1 1 0 2 2 2 0 Autophagy protein 16 (ATG16) YabA PF06156.13 AIN95245.1 - 6 7.6 6.7 1.8 9.3 3.5 1.9 2 0 0 2 2 1 0 Initiation control protein YabA UPF0449 PF15136.6 AIN95245.1 - 7.9 7.0 7.3 6.9 7.2 0.4 2.7 1 1 0 2 2 2 0 Uncharacterised protein family UPF0449 Acetyltransf_1 PF00583.25 AIN95246.1 - 6.8e-08 32.8 0.1 9.1e-08 32.4 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 AIN95246.1 - 1.2e-06 28.4 0.1 1.6e-06 28.1 0.1 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 AIN95246.1 - 3.1e-05 24.3 0.1 4.3e-05 23.9 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain DUF2606 PF10794.9 AIN95246.1 - 0.068 12.9 0.1 0.11 12.2 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2606) DUF4558 PF15104.6 AIN95247.1 - 0.00074 19.5 3.3 0.0019 18.2 3.3 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF4558) FMN_dh PF01070.18 AIN95247.1 - 0.036 13.1 0.1 0.06 12.4 0.0 1.4 1 1 0 1 1 1 0 FMN-dependent dehydrogenase ABC_tran PF00005.27 AIN95249.1 - 3.2e-47 160.5 5.2 4e-23 82.4 0.0 3.7 4 0 0 4 4 3 2 ABC transporter ABC_tran_Xtn PF12848.7 AIN95249.1 - 1.1e-24 86.3 4.1 1.1e-24 86.3 4.1 3.0 4 0 0 4 4 2 1 ABC transporter AAA_21 PF13304.6 AIN95249.1 - 1.5e-17 64.4 9.0 0.00042 20.2 0.4 4.3 3 1 1 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 AIN95249.1 - 2.9e-11 43.2 1.1 0.0059 16.1 0.1 4.3 2 2 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 AIN95249.1 - 1e-08 35.8 0.1 0.0047 17.3 0.0 2.8 2 0 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.6 AIN95249.1 - 1.1e-07 31.5 0.3 0.0043 16.8 0.0 3.0 3 0 0 3 3 2 2 P-loop containing region of AAA domain AAA_15 PF13175.6 AIN95249.1 - 1.1e-07 31.9 0.0 0.11 12.2 0.0 4.1 4 1 0 4 4 4 2 AAA ATPase domain MMR_HSR1 PF01926.23 AIN95249.1 - 1.4e-07 31.6 0.1 0.0085 16.2 0.1 3.0 2 0 0 2 2 2 2 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 AIN95249.1 - 2.1e-07 31.0 0.4 0.0016 18.4 0.1 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA_28 PF13521.6 AIN95249.1 - 1.9e-06 28.2 1.2 0.016 15.5 0.0 3.4 3 0 0 3 3 3 2 AAA domain AAA_23 PF13476.6 AIN95249.1 - 7.5e-05 23.3 11.8 0.029 14.9 0.0 4.2 5 0 0 5 5 4 2 AAA domain AAA_22 PF13401.6 AIN95249.1 - 8.1e-05 22.9 1.2 0.28 11.4 0.1 3.3 2 2 0 2 2 2 2 AAA domain AAA_33 PF13671.6 AIN95249.1 - 0.00011 22.4 3.9 0.44 10.7 0.1 3.6 2 1 0 3 3 3 2 AAA domain AAA PF00004.29 AIN95249.1 - 0.00012 22.5 0.0 1.4 9.4 0.0 3.7 4 0 0 4 4 2 2 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 AIN95249.1 - 0.00013 22.5 0.9 0.17 12.4 0.0 3.4 3 0 0 3 3 2 1 AAA domain Roc PF08477.13 AIN95249.1 - 0.00017 21.8 0.0 0.62 10.3 0.0 2.9 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase AAA_30 PF13604.6 AIN95249.1 - 0.00024 20.9 0.2 1.1 9.0 0.0 3.0 2 2 0 2 2 2 2 AAA domain NACHT PF05729.12 AIN95249.1 - 0.00042 20.3 0.1 0.81 9.6 0.0 2.6 2 0 0 2 2 2 2 NACHT domain PduV-EutP PF10662.9 AIN95249.1 - 0.0012 18.6 0.1 0.24 11.1 0.0 2.6 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation AAA_25 PF13481.6 AIN95249.1 - 0.0012 18.4 0.1 2.1 7.9 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_14 PF13173.6 AIN95249.1 - 0.0013 18.8 0.0 1.8 8.6 0.0 3.5 3 0 0 3 3 3 1 AAA domain Dynamin_N PF00350.23 AIN95249.1 - 0.0019 18.3 0.0 5.7 7.0 0.0 3.7 3 0 0 3 3 3 0 Dynamin family RNA_helicase PF00910.22 AIN95249.1 - 0.0031 17.9 0.0 0.99 9.8 0.0 2.8 2 0 0 2 2 2 1 RNA helicase AAA_5 PF07728.14 AIN95249.1 - 0.0035 17.3 0.2 3.2 7.7 0.0 3.0 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) Arf PF00025.21 AIN95249.1 - 0.0045 16.5 0.7 2.1 7.8 0.0 3.4 3 0 0 3 3 3 1 ADP-ribosylation factor family DUF815 PF05673.13 AIN95249.1 - 0.005 16.0 0.1 1 8.5 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF815) FeoB_N PF02421.18 AIN95249.1 - 0.0053 16.3 0.1 0.31 10.5 0.1 2.4 2 0 0 2 2 2 1 Ferrous iron transport protein B AAA_7 PF12775.7 AIN95249.1 - 0.0059 16.1 0.1 0.57 9.7 0.0 2.6 2 0 0 2 2 2 1 P-loop containing dynein motor region Zeta_toxin PF06414.12 AIN95249.1 - 0.0066 15.8 0.1 1.1 8.4 0.0 2.5 2 0 0 2 2 2 1 Zeta toxin TsaE PF02367.17 AIN95249.1 - 0.007 16.4 0.1 0.68 10.0 0.0 2.7 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE cobW PF02492.19 AIN95249.1 - 0.0079 15.8 0.2 1.6 8.3 0.0 2.5 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_24 PF13479.6 AIN95249.1 - 0.01 15.6 4.4 2.7 7.7 0.0 3.5 4 0 0 4 4 3 0 AAA domain Ploopntkinase3 PF18751.1 AIN95249.1 - 0.016 15.2 0.1 0.71 9.8 0.0 2.8 2 1 0 2 2 2 0 P-loop Nucleotide Kinase3 SRP54 PF00448.22 AIN95249.1 - 0.016 14.8 0.2 5.4 6.6 0.0 2.7 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_27 PF13514.6 AIN95249.1 - 0.024 14.2 0.7 7.3 6.1 0.0 3.4 3 0 0 3 3 3 0 AAA domain NB-ARC PF00931.22 AIN95249.1 - 0.026 13.7 0.0 8.2 5.5 0.0 2.5 2 0 0 2 2 2 0 NB-ARC domain NTPase_1 PF03266.15 AIN95249.1 - 0.039 13.9 0.4 8.4 6.3 0.1 3.1 3 0 0 3 3 2 0 NTPase Ras PF00071.22 AIN95249.1 - 0.051 13.2 0.1 1.3 8.6 0.0 2.5 2 0 0 2 2 2 0 Ras family Septin PF00735.18 AIN95249.1 - 0.07 12.4 1.9 2.3 7.4 0.0 2.7 3 0 0 3 3 2 0 Septin MeaB PF03308.16 AIN95249.1 - 0.078 12.0 0.1 6 5.8 0.0 2.6 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB ATPase_2 PF01637.18 AIN95249.1 - 0.17 11.8 2.1 11 5.9 0.0 3.2 4 0 0 4 4 3 0 ATPase domain predominantly from Archaea ATP_bind_1 PF03029.17 AIN95249.1 - 0.3 10.8 1.5 28 4.4 0.0 3.4 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein MobB PF03205.14 AIN95249.1 - 0.75 9.7 3.5 10 6.0 0.1 3.5 3 1 1 4 4 2 0 Molybdopterin guanine dinucleotide synthesis protein B zf-C2H2_3 PF13878.6 AIN95251.1 - 4e-13 48.9 0.0 8.6e-13 47.9 0.0 1.6 1 0 0 1 1 1 1 zinc-finger of acetyl-transferase ESCO zf-CCCH PF00642.24 AIN95252.1 - 1.6e-07 31.0 8.5 0.00024 20.9 1.0 2.7 3 0 0 3 3 3 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 AIN95252.1 - 3.1e-07 30.2 7.3 0.00089 19.2 1.3 2.6 2 0 0 2 2 2 2 Zinc finger domain RRM_1 PF00076.22 AIN95252.1 - 2e-05 24.3 0.0 0.00028 20.6 0.0 2.4 2 1 1 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Torus PF16131.5 AIN95252.1 - 0.0015 19.2 8.9 0.028 15.1 0.3 2.7 2 1 1 3 3 3 2 Torus domain zf-CCCH_3 PF15663.5 AIN95252.1 - 0.23 11.7 5.3 5.9 7.2 0.2 2.3 2 0 0 2 2 2 0 Zinc-finger containing family zf-CCCH_2 PF14608.6 AIN95252.1 - 0.82 10.2 4.1 33 5.2 0.1 2.8 2 1 0 2 2 2 0 RNA-binding, Nab2-type zinc finger zf-CCCH_4 PF18044.1 AIN95252.1 - 3.3 7.6 11.5 2 8.3 1.6 2.9 2 2 0 2 2 2 0 CCCH-type zinc finger Aldedh PF00171.22 AIN95253.1 - 2.3e-103 346.2 0.0 2.9e-103 345.8 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Pkinase PF00069.25 AIN95254.1 - 4.5e-58 196.7 0.0 5.8e-58 196.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 AIN95254.1 - 4e-29 101.7 0.0 7.6e-29 100.8 0.0 1.4 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 AIN95254.1 - 6.1e-05 22.0 0.0 9e-05 21.4 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 AIN95254.1 - 0.00041 19.4 0.1 0.0007 18.6 0.1 1.5 1 1 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 AIN95254.1 - 0.0027 17.7 1.7 1.7 8.5 0.0 2.8 2 1 1 3 3 3 2 Phosphotransferase enzyme family Kdo PF06293.14 AIN95254.1 - 0.0029 17.0 0.0 0.0057 16.0 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 AIN95254.1 - 0.027 14.1 0.1 0.058 13.0 0.1 1.5 1 1 0 1 1 1 0 RIO1 family Kinase-like PF14531.6 AIN95254.1 - 0.037 13.3 0.0 0.12 11.6 0.0 2.0 1 1 0 1 1 1 0 Kinase-like AMP-binding PF00501.28 AIN95256.1 - 9.4e-95 317.7 0.2 1.3e-94 317.2 0.2 1.1 1 0 0 1 1 1 1 AMP-binding enzyme Ribosomal_L38e PF01781.18 AIN95258.1 - 3.4e-29 100.8 4.4 4e-29 100.5 4.4 1.1 1 0 0 1 1 1 1 Ribosomal L38e protein family FYVE PF01363.21 AIN95260.1 - 6.5e-12 45.4 9.6 1.1e-11 44.7 9.6 1.4 1 0 0 1 1 1 1 FYVE zinc finger Vps23_core PF09454.10 AIN95260.1 - 0.043 13.8 2.0 1.5 8.9 0.1 2.2 2 0 0 2 2 2 0 Vps23 core domain FAD_SOX PF18371.1 AIN95260.1 - 0.089 13.2 0.6 0.15 12.4 0.6 1.3 1 0 0 1 1 1 0 Flavin adenine dinucleotide (FAD)-dependent sulfhydryl oxidase TFIIA PF03153.13 AIN95260.1 - 1.3 8.9 11.0 1.6 8.7 11.0 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit FYVE_2 PF02318.16 AIN95260.1 - 3.3 7.9 12.1 0.48 10.7 6.9 2.0 2 1 0 2 2 2 0 FYVE-type zinc finger zf-B_box PF00643.24 AIN95260.1 - 3.5 7.9 10.6 2.5 8.3 5.3 2.5 2 0 0 2 2 2 0 B-box zinc finger DUF1635 PF07795.11 AIN95261.1 - 0.001 19.0 1.4 0.21 11.4 0.0 2.4 1 1 1 2 2 2 2 Protein of unknown function (DUF1635) DUF3552 PF12072.8 AIN95261.1 - 0.0041 16.6 0.8 0.0041 16.6 0.8 3.6 3 1 0 3 3 3 2 Domain of unknown function (DUF3552) CENP-F_leu_zip PF10473.9 AIN95261.1 - 0.017 15.1 0.2 0.017 15.1 0.2 4.1 4 0 0 4 4 4 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF4407 PF14362.6 AIN95261.1 - 0.16 11.3 17.4 0.06 12.7 4.4 3.1 2 1 1 3 3 3 0 Domain of unknown function (DUF4407) DUF4226 PF10774.9 AIN95261.1 - 1.5 9.1 17.1 0.038 14.3 3.4 3.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4226) HAUS-augmin3 PF14932.6 AIN95261.1 - 3.2 7.3 20.9 0.43 10.1 0.6 3.6 4 0 0 4 4 4 0 HAUS augmin-like complex subunit 3 Spore_III_AB PF09548.10 AIN95261.1 - 3.4 7.8 8.1 0.56 10.3 0.2 3.4 4 1 0 4 4 4 0 Stage III sporulation protein AB (spore_III_AB) zf-RING_9 PF13901.6 AIN95262.1 - 3.9e-06 27.0 23.6 0.021 14.8 0.0 5.4 5 1 0 5 5 5 4 Putative zinc-RING and/or ribbon DUF1664 PF07889.12 AIN95263.1 - 0.14 12.2 0.3 0.3 11.2 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Jnk-SapK_ap_N PF09744.9 AIN95263.1 - 0.51 10.6 10.9 0.038 14.2 0.5 2.6 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 DUF2857 PF11198.8 AIN95263.1 - 2.5 7.9 13.0 0.6 9.9 2.4 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2857) DUF724 PF05266.14 AIN95264.1 - 0.0017 18.2 7.2 0.0017 18.2 7.2 7.5 3 2 3 7 7 7 2 Protein of unknown function (DUF724) DUF3867 PF12983.7 AIN95264.1 - 0.21 11.6 5.0 0.79 9.7 1.4 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF3867) TraW_N PF12477.8 AIN95265.1 - 0.2 11.6 2.6 0.4 10.7 0.3 2.8 2 0 0 2 2 2 0 Sex factor F TraW protein N terminal DDRGK PF09756.9 AIN95266.1 - 2.3e-23 82.8 23.7 3.5e-16 59.3 0.0 2.3 2 0 0 2 2 2 2 DDRGK domain GAPT PF11770.8 AIN95266.1 - 0.1 12.5 0.1 0.29 11.0 0.0 1.9 2 0 0 2 2 2 0 GRB2-binding adapter (GAPT) Nop53 PF07767.11 AIN95266.1 - 0.91 8.8 28.1 2 7.7 28.1 1.6 1 1 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) Pkinase PF00069.25 AIN95267.1 - 5.2e-32 111.2 0.0 6.6e-25 88.0 0.0 3.4 3 0 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 AIN95267.1 - 1.1e-13 51.1 0.0 3.5e-12 46.2 0.0 2.8 2 1 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 AIN95267.1 - 0.002 17.5 0.0 0.0036 16.7 0.0 1.3 1 0 0 1 1 1 1 Kinase-like SR-25 PF10500.9 AIN95267.1 - 0.005 16.5 10.5 0.005 16.5 10.5 4.2 5 0 0 5 5 5 1 Nuclear RNA-splicing-associated protein NCKAP5 PF15246.6 AIN95267.1 - 0.42 10.2 9.3 0.43 10.2 4.5 2.3 2 0 0 2 2 2 0 Nck-associated protein 5, Peripheral clock protein Macoilin PF09726.9 AIN95267.1 - 3.6 6.0 13.3 1.2 7.6 1.3 2.5 3 0 0 3 3 3 0 Macoilin family EPL1 PF10513.9 AIN95267.1 - 5.9 7.3 6.4 4 7.8 0.6 2.5 2 0 0 2 2 2 0 Enhancer of polycomb-like Gpr1_Fun34_YaaH PF01184.19 AIN95270.1 - 4e-48 163.8 14.3 5e-48 163.5 14.3 1.0 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family MFS_1 PF07690.16 AIN95271.1 - 9e-30 103.8 14.9 1.2e-19 70.5 0.2 2.2 2 0 0 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 AIN95271.1 - 1.1e-07 30.7 19.7 0.00032 19.4 6.2 3.5 2 2 1 3 3 3 2 MFS/sugar transport protein OATP PF03137.20 AIN95271.1 - 2.3e-07 29.5 2.6 3e-05 22.5 0.0 3.2 3 1 0 3 3 3 1 Organic Anion Transporter Polypeptide (OATP) family T2SSM PF04612.12 AIN95271.1 - 0.0033 17.5 0.2 0.0033 17.5 0.2 2.2 3 0 0 3 3 3 1 Type II secretion system (T2SS), protein M TMEM65 PF10507.9 AIN95271.1 - 0.016 15.1 0.3 9.5 6.2 0.0 3.7 3 1 0 3 3 3 0 Transmembrane protein 65 DUF2730 PF10805.8 AIN95271.1 - 0.85 9.7 2.8 1.2 9.2 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF2730) DUF4131 PF13567.6 AIN95271.1 - 1.8 8.2 7.5 3.7 7.2 0.0 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4131) Ribosomal_60s PF00428.19 AIN95273.1 - 6.4e-23 81.2 12.2 7.6e-23 80.9 12.2 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein Ribosomal_60s PF00428.19 AIN95274.1 - 6.4e-23 81.2 12.2 7.6e-23 80.9 12.2 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein TLD PF07534.16 AIN95275.1 - 8.9e-15 55.1 0.0 4.3e-14 52.9 0.0 1.9 2 0 0 2 2 2 1 TLD U62_UL91 PF17442.2 AIN95275.1 - 0.17 11.9 0.0 0.37 10.8 0.0 1.6 1 0 0 1 1 1 0 Functional domain of U62 and UL91 proteins NEMP PF10225.9 AIN95277.1 - 3.6 7.2 7.6 8.4 6.0 7.6 1.7 1 1 0 1 1 1 0 NEMP family Ank_2 PF12796.7 AIN95278.1 - 4.8e-32 110.4 0.0 5.4e-13 49.4 0.0 4.4 3 2 1 4 4 4 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 AIN95278.1 - 1.9e-24 85.4 1.3 2.2e-09 37.4 0.0 4.7 2 2 2 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 AIN95278.1 - 2e-22 76.8 0.4 0.0016 18.7 0.0 6.7 6 0 0 6 6 6 4 Ankyrin repeat Ank_4 PF13637.6 AIN95278.1 - 3.6e-22 78.4 6.7 1.5e-07 31.8 0.1 5.1 3 2 2 5 5 5 4 Ankyrin repeats (many copies) Ank PF00023.30 AIN95278.1 - 4.2e-18 64.9 2.7 0.00011 22.5 0.1 5.9 6 0 0 6 6 6 4 Ankyrin repeat DHHC PF01529.20 AIN95278.1 - 8.9e-09 35.6 2.3 1.1e-07 32.0 0.1 2.8 2 1 1 3 3 3 1 DHHC palmitoyltransferase PHO4 PF01384.20 AIN95280.1 - 7e-105 350.8 16.0 8.9e-105 350.4 16.0 1.1 1 0 0 1 1 1 1 Phosphate transporter family DSPc PF00782.20 AIN95281.1 - 0.032 14.0 0.2 0.077 12.8 0.2 1.5 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain RRM_1 PF00076.22 AIN95282.1 - 6.5e-13 48.3 0.3 0.00012 21.8 0.0 4.6 4 1 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DnaG_DnaB_bind PF08278.11 AIN95282.1 - 5.4 7.6 6.9 2.5 8.7 0.7 2.6 2 0 0 2 2 2 0 DNA primase DnaG DnaB-binding TruD PF01142.18 AIN95283.1 - 0.00025 20.0 0.0 0.00053 18.9 0.0 1.4 1 0 0 1 1 1 1 tRNA pseudouridine synthase D (TruD) AAA PF00004.29 AIN95284.1 - 1.3e-44 151.8 0.3 2.4e-44 150.9 0.0 1.6 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 AIN95284.1 - 8.5e-13 47.9 0.9 1.5e-12 47.1 0.0 1.9 2 0 0 2 2 1 1 AAA+ lid domain AAA_2 PF07724.14 AIN95284.1 - 1.8e-07 31.4 0.0 4.9e-07 30.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 AIN95284.1 - 2.7e-07 31.1 0.0 0.0005 20.5 0.0 2.4 1 1 1 2 2 2 2 AAA ATPase domain Prot_ATP_ID_OB PF16450.5 AIN95284.1 - 3.7e-07 30.0 0.2 8.5e-07 28.8 0.2 1.6 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_5 PF07728.14 AIN95284.1 - 1e-06 28.8 0.1 1e-05 25.5 0.1 2.4 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 AIN95284.1 - 4.5e-06 26.5 0.0 1.3e-05 25.0 0.0 1.7 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 AIN95284.1 - 6e-05 23.3 0.1 0.022 15.0 0.0 2.4 1 1 1 2 2 2 1 AAA domain DUF815 PF05673.13 AIN95284.1 - 0.00041 19.6 0.0 0.00091 18.5 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF815) TIP49 PF06068.13 AIN95284.1 - 0.00053 19.3 0.0 0.0011 18.2 0.0 1.5 1 0 0 1 1 1 1 TIP49 P-loop domain IstB_IS21 PF01695.17 AIN95284.1 - 0.0014 18.4 0.0 0.003 17.3 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein Mg_chelatase PF01078.21 AIN95284.1 - 0.0017 17.8 0.1 0.0034 16.8 0.1 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.22 AIN95284.1 - 0.0017 18.7 0.0 0.0053 17.1 0.0 1.9 2 0 0 2 2 1 1 RNA helicase AAA_24 PF13479.6 AIN95284.1 - 0.0021 17.8 0.1 0.0042 16.8 0.0 1.6 2 0 0 2 2 1 1 AAA domain AAA_7 PF12775.7 AIN95284.1 - 0.0023 17.5 0.0 0.0074 15.8 0.0 1.7 1 1 0 1 1 1 1 P-loop containing dynein motor region AAA_14 PF13173.6 AIN95284.1 - 0.0035 17.4 0.0 0.0074 16.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain Parvo_NS1 PF01057.17 AIN95284.1 - 0.0055 15.8 0.0 0.011 14.9 0.0 1.4 1 0 0 1 1 1 1 Parvovirus non-structural protein NS1 AAA_18 PF13238.6 AIN95284.1 - 0.0056 17.2 0.1 0.021 15.3 0.0 2.0 2 0 0 2 2 2 1 AAA domain ATPase PF06745.13 AIN95284.1 - 0.011 15.1 3.0 0.098 12.0 0.1 2.8 2 1 1 3 3 3 0 KaiC AAA_25 PF13481.6 AIN95284.1 - 0.013 15.1 0.1 0.1 12.1 0.0 2.3 2 0 0 2 2 2 0 AAA domain Sigma54_activat PF00158.26 AIN95284.1 - 0.019 14.7 0.1 0.062 13.0 0.1 2.0 1 1 0 1 1 1 0 Sigma-54 interaction domain AAA_3 PF07726.11 AIN95284.1 - 0.023 14.6 0.0 0.051 13.5 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.6 AIN95284.1 - 0.023 14.9 0.0 0.051 13.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain PhoH PF02562.16 AIN95284.1 - 0.027 13.9 0.2 0.067 12.6 0.2 1.6 1 0 0 1 1 1 0 PhoH-like protein ABC_tran PF00005.27 AIN95284.1 - 0.029 14.9 0.1 0.19 12.2 0.0 2.3 2 0 0 2 2 2 0 ABC transporter ATPase_2 PF01637.18 AIN95284.1 - 0.031 14.2 0.9 1.2 8.9 0.0 2.8 2 1 1 3 3 3 0 ATPase domain predominantly from Archaea TsaE PF02367.17 AIN95284.1 - 0.031 14.3 0.0 0.066 13.2 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Prot_ATP_OB_N PF17758.1 AIN95284.1 - 0.037 13.7 0.0 0.097 12.3 0.0 1.7 1 0 0 1 1 1 0 Proteasomal ATPase OB N-terminal domain AAA_33 PF13671.6 AIN95284.1 - 0.056 13.6 0.1 0.14 12.3 0.0 1.8 2 0 0 2 2 1 0 AAA domain AAA_11 PF13086.6 AIN95284.1 - 0.057 13.2 0.3 0.79 9.5 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 AIN95284.1 - 0.071 12.8 0.0 0.17 11.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 AIN95284.1 - 0.074 13.0 0.1 0.35 10.8 0.0 2.0 1 1 1 2 2 2 0 NACHT domain AAA_19 PF13245.6 AIN95284.1 - 0.13 12.6 0.2 0.34 11.2 0.2 1.7 1 1 0 1 1 1 0 AAA domain FAM176 PF14851.6 AIN95285.1 - 0.077 12.7 0.0 0.077 12.7 0.0 3.6 3 2 1 4 4 4 0 FAM176 family ADH_zinc_N PF00107.26 AIN95287.1 - 2.6e-19 69.5 0.0 5.8e-19 68.4 0.0 1.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 AIN95287.1 - 4.5e-16 60.1 0.0 1.1e-15 58.8 0.0 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 AIN95287.1 - 1.2e-09 38.1 0.0 4.5e-09 36.2 0.0 2.1 2 1 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain Helicase_C_2 PF13307.6 AIN95289.1 - 9.6e-41 139.8 0.0 2.5e-40 138.4 0.0 1.8 1 0 0 1 1 1 1 Helicase C-terminal domain DEAD_2 PF06733.15 AIN95289.1 - 7.6e-22 77.8 0.2 6.1e-08 32.5 0.0 4.3 4 0 0 4 4 4 4 DEAD_2 DUF3246 PF11596.8 AIN95289.1 - 0.02 14.3 0.5 0.24 10.8 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3246) Methyltransf_31 PF13847.6 AIN95290.1 - 3.2e-09 36.7 0.0 6e-09 35.9 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 AIN95290.1 - 6.3e-08 33.2 0.0 2.1e-07 31.6 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 AIN95290.1 - 9.6e-05 23.0 0.0 0.00038 21.1 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain tRNA_U5-meth_tr PF05958.11 AIN95290.1 - 0.0012 17.9 0.0 0.0017 17.4 0.0 1.2 1 0 0 1 1 1 1 tRNA (Uracil-5-)-methyltransferase PrmA PF06325.13 AIN95290.1 - 0.0012 18.3 0.0 0.0022 17.5 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_9 PF08003.11 AIN95290.1 - 0.0021 17.1 0.0 0.0051 15.8 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF1698) Methyltransf_12 PF08242.12 AIN95290.1 - 0.004 17.9 0.0 0.011 16.5 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 AIN95290.1 - 0.0073 15.9 0.0 0.014 14.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_24 PF13578.6 AIN95290.1 - 0.11 13.5 0.1 0.42 11.7 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase domain MeaB PF03308.16 AIN95291.1 - 2.7e-74 249.5 0.1 3.9e-74 249.0 0.1 1.2 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB cobW PF02492.19 AIN95291.1 - 1e-07 31.8 0.0 2.8e-07 30.3 0.0 1.7 1 1 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain ParA PF10609.9 AIN95291.1 - 0.0086 15.5 0.3 1.2 8.5 0.1 2.2 2 0 0 2 2 2 2 NUBPL iron-transfer P-loop NTPase AAA_16 PF13191.6 AIN95291.1 - 0.011 16.1 0.1 0.028 14.8 0.1 1.6 1 0 0 1 1 1 0 AAA ATPase domain AAA_29 PF13555.6 AIN95291.1 - 0.021 14.6 0.0 0.047 13.4 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_22 PF13401.6 AIN95291.1 - 0.029 14.7 0.4 0.3 11.4 0.0 2.5 2 1 0 2 2 2 0 AAA domain AAA_10 PF12846.7 AIN95291.1 - 0.1 11.5 0.0 0.19 10.6 0.0 1.4 1 0 0 1 1 1 0 AAA-like domain SMC_N PF02463.19 AIN95291.1 - 0.17 11.3 0.0 0.31 10.4 0.0 1.3 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain YbaB_DNA_bd PF02575.16 AIN95293.1 - 0.071 13.3 0.0 14 5.9 0.0 2.4 2 0 0 2 2 2 0 YbaB/EbfC DNA-binding family Mito_fiss_reg PF05308.11 AIN95293.1 - 0.26 11.3 3.3 0.48 10.5 3.3 1.4 1 0 0 1 1 1 0 Mitochondrial fission regulator CAP_N PF01213.19 AIN95293.1 - 3.4 7.1 6.6 5.2 6.4 6.6 1.3 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Dis3l2_C_term PF17877.1 AIN95295.1 - 0.053 13.8 0.0 0.11 12.8 0.0 1.5 1 0 0 1 1 1 0 DIS3-like exonuclease 2 C terminal EamA PF00892.20 AIN95296.1 - 0.0086 16.2 5.8 0.0086 16.2 5.8 3.8 3 1 1 4 4 4 2 EamA-like transporter family CRT-like PF08627.10 AIN95296.1 - 2 7.3 11.2 0.22 10.4 2.9 2.6 2 1 1 3 3 3 0 CRT-like, chloroquine-resistance transporter-like AAA_16 PF13191.6 AIN95297.1 - 0.0059 17.0 0.2 0.015 15.7 0.1 1.7 2 0 0 2 2 2 1 AAA ATPase domain RecA PF00154.21 AIN95297.1 - 0.026 14.0 0.0 0.04 13.4 0.0 1.2 1 0 0 1 1 1 0 recA bacterial DNA recombination protein AAA_14 PF13173.6 AIN95297.1 - 0.031 14.3 0.0 0.071 13.2 0.0 1.6 2 0 0 2 2 2 0 AAA domain HEM4 PF02602.15 AIN95298.1 - 5.8e-56 189.4 0.2 6.7e-56 189.2 0.2 1.0 1 0 0 1 1 1 1 Uroporphyrinogen-III synthase HemD DUF1467 PF07330.12 AIN95298.1 - 0.081 12.9 0.0 0.16 11.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1467) DEAD PF00270.29 AIN95299.1 - 2.6e-20 72.9 0.0 7.3e-19 68.2 0.0 2.8 3 0 0 3 3 3 1 DEAD/DEAH box helicase ResIII PF04851.15 AIN95299.1 - 5.7e-09 36.2 0.0 1.2e-08 35.1 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 AIN95299.1 - 5.4e-05 23.5 0.1 0.00018 21.8 0.1 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Beta_helix PF13229.6 AIN95300.1 - 0.00052 19.9 2.7 18 5.2 0.0 6.0 7 1 0 7 7 7 2 Right handed beta helix region CxC4 PF18717.1 AIN95300.1 - 0.11 12.4 0.2 0.45 10.4 0.2 2.1 1 0 0 1 1 1 0 CxC4 like cysteine cluster associated with KDZ transposases tRNA_edit PF04073.15 AIN95301.1 - 1.5e-19 70.3 0.1 5.3e-19 68.5 0.1 1.8 1 1 0 1 1 1 1 Aminoacyl-tRNA editing domain bact-PGI_C PF10432.9 AIN95301.1 - 0.086 12.9 0.3 0.29 11.2 0.1 1.9 2 0 0 2 2 2 0 Bacterial phospho-glucose isomerase C-terminal SIS domain COX17 PF05051.13 AIN95304.1 - 4.7e-15 55.7 7.4 6.1e-15 55.3 7.4 1.1 1 0 0 1 1 1 1 Cytochrome C oxidase copper chaperone (COX17) TatD_DNase PF01026.21 AIN95305.1 - 1.2e-49 169.0 0.8 2.1e-49 168.2 0.8 1.4 1 0 0 1 1 1 1 TatD related DNase LRR_4 PF12799.7 AIN95307.1 - 2e-12 47.1 6.8 9.1e-05 22.8 0.0 3.8 3 0 0 3 3 3 3 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 AIN95307.1 - 5e-10 39.2 1.7 0.0015 18.0 1.0 3.8 3 1 1 4 4 4 3 Leucine-rich repeat Ubiquitin_2 PF14560.6 AIN95307.1 - 6.1e-10 39.4 0.0 1.2e-09 38.5 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-like domain LRR_8 PF13855.6 AIN95307.1 - 3e-06 26.9 11.8 0.14 12.0 0.1 4.3 2 2 0 3 3 3 3 Leucine rich repeat ubiquitin PF00240.23 AIN95307.1 - 0.0021 17.8 0.2 0.023 14.4 0.2 2.3 1 1 0 1 1 1 1 Ubiquitin family LRR_6 PF13516.6 AIN95307.1 - 0.0022 17.9 9.3 0.53 10.5 0.1 5.0 4 0 0 4 4 4 1 Leucine Rich repeat LRR_1 PF00560.33 AIN95307.1 - 0.38 11.5 5.6 90 4.2 0.0 4.9 5 0 0 5 5 5 0 Leucine Rich Repeat Pkinase PF00069.25 AIN95308.1 - 1.2e-51 175.6 0.0 4.4e-29 101.7 0.0 3.2 3 0 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.17 AIN95308.1 - 3.9e-23 82.1 0.0 1.6e-08 34.2 0.0 3.2 3 0 0 3 3 3 3 Protein tyrosine kinase Pkinase_fungal PF17667.1 AIN95308.1 - 0.0045 15.8 0.2 0.0094 14.8 0.0 1.5 2 0 0 2 2 2 1 Fungal protein kinase Kinase-like PF14531.6 AIN95308.1 - 0.076 12.3 0.0 0.18 11.1 0.0 1.5 2 0 0 2 2 2 0 Kinase-like RNA_pol_Rpb4 PF03874.16 AIN95309.1 - 0.054 13.8 0.0 0.24 11.7 0.0 2.0 2 0 0 2 2 2 0 RNA polymerase Rpb4 6PF2K PF01591.18 AIN95310.1 - 1.5e-62 210.8 0.0 2.2e-62 210.3 0.0 1.2 1 0 0 1 1 1 1 6-phosphofructo-2-kinase Ank_2 PF12796.7 AIN95310.1 - 3.8e-12 46.6 0.2 1.2e-11 45.0 0.2 1.8 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 AIN95310.1 - 1.7e-09 38.1 0.2 6e-09 36.3 0.2 2.1 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 AIN95310.1 - 4.1e-08 33.3 1.5 2.1e-07 31.1 0.5 2.6 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 AIN95310.1 - 1.5e-06 28.3 1.0 0.00073 19.9 0.0 3.4 3 0 0 3 3 3 1 Ankyrin repeat AAA_33 PF13671.6 AIN95310.1 - 7.1e-06 26.2 0.5 2.2e-05 24.7 0.0 2.1 2 0 0 2 2 2 1 AAA domain Ank_3 PF13606.6 AIN95310.1 - 8.4e-06 25.8 0.1 0.081 13.5 0.0 2.9 2 0 0 2 2 2 2 Ankyrin repeat His_Phos_1 PF00300.22 AIN95310.1 - 0.00019 21.2 0.0 0.079 12.6 0.0 2.7 2 0 0 2 2 2 2 Histidine phosphatase superfamily (branch 1) Vir_act_alpha_C PF10400.9 AIN95310.1 - 0.072 13.8 0.5 0.2 12.3 0.5 1.7 1 0 0 1 1 1 0 Virulence activator alpha C-term Exonuc_VII_L PF02601.15 AIN95312.1 - 7.9 5.9 13.9 0.48 10.0 6.7 2.6 2 0 0 2 2 2 0 Exonuclease VII, large subunit zf-C6H2 PF15801.5 AIN95314.1 - 1.2e-09 38.3 8.7 2.4e-09 37.3 8.7 1.5 1 0 0 1 1 1 1 zf-MYND-like zinc finger, mRNA-binding zf-MYND PF01753.18 AIN95314.1 - 0.00038 20.5 7.1 0.00077 19.5 7.1 1.5 1 0 0 1 1 1 1 MYND finger Prok-RING_4 PF14447.6 AIN95314.1 - 0.037 13.9 0.8 0.087 12.7 0.8 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 LRR_4 PF12799.7 AIN95317.1 - 1.5e-06 28.5 11.1 0.088 13.3 0.0 4.8 3 1 3 6 6 6 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 AIN95317.1 - 0.00019 21.1 17.4 0.00093 18.9 2.0 3.8 2 1 0 3 3 3 2 Leucine rich repeat LRR_1 PF00560.33 AIN95317.1 - 1.4 9.7 6.3 91 4.2 0.0 4.7 4 1 0 4 4 4 0 Leucine Rich Repeat LRR_6 PF13516.6 AIN95317.1 - 3.7 7.8 12.8 49 4.3 0.2 5.7 6 0 0 6 6 6 0 Leucine Rich repeat NIF PF03031.18 AIN95319.1 - 1.2e-25 90.1 0.1 1.9e-18 66.7 0.0 2.6 3 0 0 3 3 3 2 NLI interacting factor-like phosphatase Brix PF04427.18 AIN95320.1 - 1.6e-33 116.4 0.1 2.3e-33 116.0 0.1 1.2 1 0 0 1 1 1 1 Brix domain SLX9 PF15341.6 AIN95320.1 - 4.6 7.6 15.0 2.7 8.4 12.2 1.9 2 1 0 2 2 2 0 Ribosome biogenesis protein SLX9 Pyrophosphatase PF00719.19 AIN95321.1 - 8.1e-42 142.7 0.0 1.1e-41 142.4 0.0 1.1 1 0 0 1 1 1 1 Inorganic pyrophosphatase Got1 PF04178.12 AIN95322.1 - 4.8e-28 97.9 21.1 7e-28 97.3 21.1 1.3 1 0 0 1 1 1 1 Got1/Sft2-like family IBV_3C PF03620.13 AIN95322.1 - 0.056 13.9 1.6 0.12 12.9 1.6 1.6 1 0 0 1 1 1 0 IBV 3C protein ECF_trnsprt PF12822.7 AIN95322.1 - 3 7.9 13.9 0.84 9.7 2.7 2.2 1 1 0 2 2 2 0 ECF transporter, substrate-specific component Amidohydro_3 PF07969.11 AIN95323.1 - 3.9e-61 208.0 7.1 5.4e-61 207.5 7.1 1.2 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_1 PF01979.20 AIN95323.1 - 1.7e-15 57.2 1.5 3.9e-11 42.9 0.5 3.0 2 1 0 2 2 2 2 Amidohydrolase family Cu-oxidase_2 PF07731.14 AIN95325.1 - 1.3e-20 73.5 0.7 1.3e-20 73.5 0.7 3.2 4 0 0 4 4 4 1 Multicopper oxidase Cu-oxidase_3 PF07732.15 AIN95325.1 - 3.9e-10 39.8 4.9 7.3e-07 29.2 1.3 4.0 3 1 0 3 3 3 2 Multicopper oxidase MORN PF02493.20 AIN95327.1 - 9.9e-23 78.6 37.7 8.7e-06 25.3 1.3 7.6 8 1 0 8 8 8 6 MORN repeat Tudor_2 PF18104.1 AIN95327.1 - 0.057 13.1 0.5 5 6.9 0.0 3.2 2 1 1 3 3 3 0 Jumonji domain-containing protein 2A Tudor domain EIF_2_alpha PF07541.12 AIN95328.1 - 1.4e-16 60.7 0.0 4.3e-15 55.8 0.0 2.2 1 1 1 2 2 2 1 Eukaryotic translation initiation factor 2 alpha subunit S1 PF00575.23 AIN95328.1 - 1.6e-11 44.3 0.5 3.7e-11 43.2 0.5 1.6 1 0 0 1 1 1 1 S1 RNA binding domain EXOSC1 PF10447.9 AIN95328.1 - 0.031 14.9 0.1 0.058 14.0 0.1 1.6 1 1 0 1 1 1 0 Exosome component EXOSC1/CSL4 Ntox35 PF15534.6 AIN95328.1 - 0.081 13.4 0.0 0.5 10.8 0.0 2.1 2 0 0 2 2 2 0 Bacterial toxin 35 E1-E2_ATPase PF00122.20 AIN95329.1 - 2.3e-47 160.8 0.7 2.3e-47 160.8 0.7 2.2 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 AIN95329.1 - 1.6e-43 148.5 6.0 1.6e-43 148.5 6.0 2.2 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 AIN95329.1 - 2.5e-20 73.7 0.6 2.2e-19 70.6 0.6 2.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 AIN95329.1 - 4.7e-17 61.9 0.1 1.2e-16 60.5 0.1 1.8 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 AIN95329.1 - 4.3e-13 48.8 0.9 6.7e-13 48.1 0.0 1.8 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 AIN95329.1 - 1.4e-07 31.5 1.5 5.1e-06 26.4 0.9 2.4 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 AIN95329.1 - 0.024 15.0 0.0 0.073 13.5 0.0 1.9 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase PDEase_I PF00233.19 AIN95330.1 - 1.4e-22 80.6 0.4 2e-22 80.1 0.4 1.2 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase TIR_2 PF13676.6 AIN95330.1 - 0.15 12.7 0.0 0.4 11.3 0.0 1.6 1 0 0 1 1 1 0 TIR domain zf-CCCH_4 PF18044.1 AIN95332.1 - 4.4 7.2 8.2 1.4 8.8 4.3 2.3 2 0 0 2 2 2 0 CCCH-type zinc finger Topo_C_assoc PF14370.6 AIN95335.1 - 1.3e-27 95.5 0.2 2e-27 94.9 0.2 1.3 1 0 0 1 1 1 1 C-terminal topoisomerase domain SPX PF03105.19 AIN95335.1 - 0.016 15.1 6.0 0.017 15.1 6.0 1.1 1 0 0 1 1 1 0 SPX domain DUF4614 PF15391.6 AIN95335.1 - 0.022 14.8 11.1 0.04 13.9 11.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) Apt1 PF10351.9 AIN95335.1 - 0.086 11.7 6.6 0.093 11.6 6.6 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Macoilin PF09726.9 AIN95335.1 - 0.096 11.2 6.5 0.1 11.1 6.5 1.1 1 0 0 1 1 1 0 Macoilin family PI3K_1B_p101 PF10486.9 AIN95335.1 - 0.65 7.7 5.5 0.74 7.5 5.5 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit RAP1 PF07218.11 AIN95335.1 - 3.6 5.7 19.0 5.2 5.2 19.0 1.2 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Methyltransf_25 PF13649.6 AIN95336.1 - 0.00026 21.7 0.1 0.00065 20.4 0.1 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 AIN95336.1 - 0.0012 18.7 0.0 0.0016 18.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 AIN95336.1 - 0.013 16.3 0.0 0.02 15.6 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.12 AIN95336.1 - 0.17 12.6 0.1 0.32 11.7 0.1 1.5 1 0 0 1 1 1 0 Methyltransferase domain CorA PF01544.18 AIN95337.1 - 0.036 13.4 1.0 0.041 13.2 1.0 1.1 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein DASH_Dam1 PF08653.10 AIN95337.1 - 0.13 12.1 0.2 0.2 11.5 0.2 1.3 1 0 0 1 1 1 0 DASH complex subunit Dam1 FlaC_arch PF05377.11 AIN95337.1 - 0.28 11.6 0.3 0.28 11.6 0.3 1.6 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) DUF3584 PF12128.8 AIN95339.1 - 0.015 12.9 10.7 0.021 12.4 10.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DAHP_synth_1 PF00793.20 AIN95339.1 - 0.035 13.0 0.1 0.055 12.3 0.1 1.2 1 0 0 1 1 1 0 DAHP synthetase I family eIF3_N PF09440.10 AIN95339.1 - 0.52 10.7 6.9 1.1 9.7 0.3 2.3 1 1 1 2 2 2 0 eIF3 subunit 6 N terminal domain CP12 PF02672.15 AIN95339.1 - 2 9.2 0.0 2 9.2 0.0 3.3 4 0 0 4 4 4 0 CP12 domain PXA PF02194.15 AIN95340.1 - 0.26 11.2 2.6 0.23 11.4 1.2 1.6 2 0 0 2 2 2 0 PXA domain ArnB_C PF18677.1 AIN95340.1 - 1.3 9.1 4.4 0.54 10.4 0.8 2.2 3 0 0 3 3 3 0 Archaellum regulatory network B, C-terminal domain KH_6 PF15985.5 AIN95341.1 - 3.5e-09 36.9 0.0 8.1e-09 35.7 0.0 1.7 1 1 0 1 1 1 1 KH domain Rib_hydrolayse PF02267.17 AIN95343.1 - 0.14 11.6 0.1 0.22 10.9 0.1 1.3 1 0 0 1 1 1 0 ADP-ribosyl cyclase VSP PF03302.13 AIN95345.1 - 8.7e-06 24.8 51.3 0.00017 20.6 12.6 4.2 1 1 2 3 3 3 3 Giardia variant-specific surface protein cEGF PF12662.7 AIN95345.1 - 0.035 14.0 0.5 0.035 14.0 0.5 5.9 6 1 0 6 6 6 0 Complement Clr-like EGF-like DUF5075 PF16825.5 AIN95346.1 - 0.0014 18.4 3.5 0.028 14.1 3.5 2.3 1 1 0 1 1 1 1 IGP family C-type lectin domain Toprim_4 PF13662.6 AIN95346.1 - 0.087 13.3 0.0 0.17 12.4 0.0 1.4 1 0 0 1 1 1 0 Toprim domain T2SSM PF04612.12 AIN95347.1 - 0.02 15.0 0.1 0.028 14.5 0.1 1.2 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein M Lectin_N PF03954.14 AIN95347.1 - 0.039 13.7 0.0 0.062 13.0 0.0 1.3 1 0 0 1 1 1 0 Hepatic lectin, N-terminal domain Shisa PF13908.6 AIN95347.1 - 2.1 8.5 9.9 0.26 11.5 4.1 2.0 1 1 1 2 2 2 0 Wnt and FGF inhibitory regulator GRAM PF02893.20 AIN95348.1 - 6.9e-06 25.9 0.0 4.8e-05 23.2 0.0 2.4 2 1 0 2 2 2 1 GRAM domain PseudoU_synth_2 PF00849.22 AIN95349.1 - 8.1e-38 130.0 0.0 1.4e-37 129.3 0.0 1.4 1 0 0 1 1 1 1 RNA pseudouridylate synthase TPR_2 PF07719.17 AIN95350.1 - 0.0059 16.6 3.4 6.2 7.2 0.0 4.0 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.28 AIN95350.1 - 0.012 15.5 2.6 4.1 7.4 0.1 3.4 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.6 AIN95350.1 - 0.083 13.2 7.9 0.15 12.4 0.1 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat MRP-L47 PF06984.13 AIN95351.1 - 2.2e-28 98.2 0.4 1.1e-27 96.0 0.1 2.2 2 0 0 2 2 2 1 Mitochondrial 39-S ribosomal protein L47 (MRP-L47) Tnp_22_trimer PF17489.2 AIN95351.1 - 0.02 14.8 0.8 0.047 13.7 0.8 1.6 1 0 0 1 1 1 0 L1 transposable element trimerization domain PRIMA1 PF16101.5 AIN95351.1 - 1.9 8.6 5.7 6 6.9 1.1 2.3 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 A_deaminase PF00962.22 AIN95352.1 - 2.2e-92 309.9 0.0 4.8e-67 226.6 0.0 3.2 3 0 0 3 3 3 2 Adenosine/AMP deaminase T2SSM_b PF10741.9 AIN95352.1 - 2.6 7.9 4.9 4.5 7.1 0.0 3.5 4 0 0 4 4 4 0 Type II secretion system (T2SS), protein M subtype b ADH_N PF08240.12 AIN95353.1 - 9.5e-07 28.7 0.7 1.9e-06 27.7 0.7 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 AIN95353.1 - 0.006 16.6 0.0 0.013 15.5 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase DUF4164 PF13747.6 AIN95354.1 - 0.0027 17.9 0.1 0.0079 16.4 0.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4164) DUF1016_N PF17761.1 AIN95354.1 - 0.056 13.6 0.0 0.24 11.5 0.0 1.9 2 0 0 2 2 2 0 DUF1016 N-terminal domain Glyco_hydro_32N PF00251.20 AIN95355.1 - 3.3e-55 187.8 5.2 4.4e-55 187.4 5.2 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 N-terminal domain Glyco_hydro_32C PF08244.12 AIN95355.1 - 3.2e-13 50.0 0.0 1e-12 48.3 0.0 1.8 1 1 0 1 1 1 1 Glycosyl hydrolases family 32 C terminal PAN_1 PF00024.26 AIN95355.1 - 1.2e-05 25.1 1.7 2.5e-05 24.1 1.7 1.5 1 0 0 1 1 1 1 PAN domain DUF5074 PF16819.5 AIN95355.1 - 0.0037 17.3 0.7 2 8.5 0.0 3.2 3 1 0 3 3 3 2 Domain of unknown function (DUF5074) PAN_4 PF14295.6 AIN95355.1 - 0.014 15.3 1.2 0.043 13.7 1.2 1.8 1 0 0 1 1 1 0 PAN domain RET_CLD3 PF17812.1 AIN95355.1 - 0.098 12.9 0.1 0.23 11.7 0.1 1.6 1 0 0 1 1 1 0 RET Cadherin like domain 3 RNB PF00773.19 AIN95356.1 - 8.3e-53 179.8 0.0 1.2e-51 176.0 0.0 2.1 2 0 0 2 2 2 2 RNB domain Arf PF00025.21 AIN95357.1 - 1.4e-53 180.9 0.0 1.6e-53 180.7 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 AIN95357.1 - 9.6e-16 58.1 0.0 1.3e-15 57.7 0.0 1.1 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 AIN95357.1 - 1.1e-14 54.4 0.0 1.2e-14 54.3 0.0 1.0 1 0 0 1 1 1 1 Ras family SRPRB PF09439.10 AIN95357.1 - 1.3e-11 44.3 0.0 1.5e-11 44.1 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 AIN95357.1 - 2e-09 37.2 0.0 2.5e-09 36.8 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region G-alpha PF00503.20 AIN95357.1 - 6.3e-09 35.5 0.5 1.6e-05 24.3 0.0 2.3 1 1 1 2 2 2 2 G-protein alpha subunit MMR_HSR1 PF01926.23 AIN95357.1 - 6e-07 29.5 0.0 7.8e-07 29.2 0.0 1.1 1 0 0 1 1 1 1 50S ribosome-binding GTPase ABC_tran PF00005.27 AIN95357.1 - 0.0047 17.5 0.0 0.017 15.7 0.0 1.7 1 1 0 1 1 1 1 ABC transporter Urocanase_N PF17391.2 AIN95357.1 - 0.028 14.1 0.0 0.055 13.2 0.0 1.5 1 0 0 1 1 1 0 Urocanase N-terminal domain AAA_21 PF13304.6 AIN95357.1 - 0.15 11.9 0.1 0.22 11.3 0.1 1.2 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 AIN95357.1 - 0.24 11.1 0.1 0.29 10.8 0.1 1.2 1 0 0 1 1 1 0 AAA ATPase domain zf-MYND PF01753.18 AIN95358.1 - 0.00026 21.0 9.4 0.00087 19.3 9.4 2.0 1 0 0 1 1 1 1 MYND finger PhyH PF05721.13 AIN95360.1 - 2e-43 149.2 0.0 2.6e-43 148.7 0.0 1.1 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Shisa PF13908.6 AIN95361.1 - 0.00014 22.2 0.5 0.0003 21.1 0.1 1.7 2 0 0 2 2 2 1 Wnt and FGF inhibitory regulator CCSMST1 PF15013.6 AIN95361.1 - 0.00095 19.3 0.1 0.0022 18.1 0.1 1.6 1 0 0 1 1 1 1 CCSMST1 family FAM163 PF15069.6 AIN95361.1 - 0.03 14.8 0.1 0.069 13.6 0.1 1.6 1 0 0 1 1 1 0 FAM163 family FixS PF03597.15 AIN95361.1 - 0.035 13.8 0.0 0.035 13.8 0.0 1.8 2 0 0 2 2 2 0 Cytochrome oxidase maturation protein cbb3-type DUF3357 PF11837.8 AIN95361.1 - 0.042 14.3 0.7 0.32 11.5 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3357) EphA2_TM PF14575.6 AIN95361.1 - 0.13 13.2 0.1 0.13 13.2 0.1 2.0 2 1 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain TMEM154 PF15102.6 AIN95361.1 - 0.95 9.4 2.7 1.1 9.1 0.3 2.1 1 1 1 2 2 2 0 TMEM154 protein family TMIE PF16038.5 AIN95361.1 - 1 9.2 6.3 2 8.3 6.3 1.3 1 0 0 1 1 1 0 TMIE protein ANAPC10 PF03256.16 AIN95362.1 - 8e-53 178.8 0.1 5.4e-52 176.1 0.1 1.9 1 1 0 1 1 1 1 Anaphase-promoting complex, subunit 10 (APC10) TPR_1 PF00515.28 AIN95364.1 - 9.1e-11 41.1 1.3 0.00032 20.4 0.0 3.1 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.17 AIN95364.1 - 2.7e-08 33.3 11.3 2.8e-05 23.9 0.2 4.2 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.6 AIN95364.1 - 5.5e-07 29.3 0.7 0.0077 16.4 0.0 3.4 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.6 AIN95364.1 - 4e-06 27.2 1.1 0.0041 17.8 0.0 5.8 5 2 1 6 6 6 2 Tetratricopeptide repeat TPR_11 PF13414.6 AIN95364.1 - 8.5e-06 25.4 5.0 0.0085 15.8 0.4 2.6 2 0 0 2 2 2 2 TPR repeat TPR_12 PF13424.6 AIN95364.1 - 0.011 16.0 13.8 0.33 11.3 0.1 5.3 4 1 2 6 6 6 0 Tetratricopeptide repeat SNAP PF14938.6 AIN95364.1 - 0.027 13.9 6.3 0.057 12.8 0.8 2.6 3 0 0 3 3 3 0 Soluble NSF attachment protein, SNAP TPR_9 PF13371.6 AIN95364.1 - 0.03 14.5 7.9 0.59 10.3 0.3 4.2 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_21 PF09976.9 AIN95364.1 - 0.041 13.6 0.1 0.041 13.6 0.1 3.4 3 1 1 4 4 4 0 Tetratricopeptide repeat-like domain TPR_6 PF13174.6 AIN95364.1 - 0.054 14.2 3.7 1.6 9.6 0.1 3.7 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_19 PF14559.6 AIN95364.1 - 0.083 13.4 0.2 0.083 13.4 0.2 4.7 5 2 0 5 5 4 0 Tetratricopeptide repeat COMMD1_N PF17221.3 AIN95364.1 - 0.12 12.6 2.4 5.2 7.4 0.2 2.8 2 1 1 3 3 3 0 COMMD1 N-terminal domain TPR_7 PF13176.6 AIN95364.1 - 0.63 10.2 3.7 1.9 8.7 0.1 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat Alkyl_sulf_dimr PF14863.6 AIN95364.1 - 1.7 9.1 7.4 10 6.6 0.1 3.1 3 0 0 3 3 3 0 Alkyl sulfatase dimerisation TPR_17 PF13431.6 AIN95364.1 - 5 7.7 7.8 37 5.0 0.0 4.9 6 1 0 6 6 5 0 Tetratricopeptide repeat Pkinase PF00069.25 AIN95365.1 - 1.2e-40 139.5 0.0 1.5e-21 77.0 0.0 4.8 4 1 0 4 4 4 4 Protein kinase domain Pkinase_Tyr PF07714.17 AIN95365.1 - 1e-32 113.5 0.1 8.6e-17 61.3 0.0 4.2 4 0 0 4 4 4 4 Protein tyrosine kinase Pkinase_fungal PF17667.1 AIN95365.1 - 0.0025 16.7 0.1 0.0077 15.1 0.0 1.7 1 1 0 1 1 1 1 Fungal protein kinase APH PF01636.23 AIN95365.1 - 0.1 12.5 2.1 0.97 9.3 0.0 2.7 2 0 0 2 2 2 0 Phosphotransferase enzyme family Peptidase_C2 PF00648.21 AIN95366.1 - 1.5e-55 188.3 0.0 2.2e-55 187.8 0.0 1.2 1 0 0 1 1 1 1 Calpain family cysteine protease DUF1935 PF09149.10 AIN95366.1 - 8.9e-33 112.8 0.0 1.9e-32 111.7 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1935) Lyase_1 PF00206.20 AIN95367.1 - 3e-49 168.1 0.0 4.3e-49 167.6 0.0 1.2 1 0 0 1 1 1 1 Lyase ASL_C PF08328.11 AIN95367.1 - 2.2e-45 153.4 0.0 4.1e-45 152.6 0.0 1.5 1 0 0 1 1 1 1 Adenylosuccinate lyase C-terminal Thoc2 PF11732.8 AIN95367.1 - 0.078 13.0 0.0 0.18 11.9 0.0 1.5 1 0 0 1 1 1 0 Transcription- and export-related complex subunit Apolipo_F PF15148.6 AIN95368.1 - 0.096 12.2 0.5 0.19 11.2 0.5 1.4 1 0 0 1 1 1 0 Apolipoprotein F N_Asn_amidohyd PF14736.6 AIN95368.1 - 0.29 10.3 5.6 0.32 10.1 0.0 3.5 4 1 1 5 5 5 0 Protein N-terminal asparagine amidohydrolase Ribosomal_L5_C PF00673.21 AIN95369.1 - 8.3e-21 74.0 0.0 1.3e-20 73.3 0.0 1.3 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.19 AIN95369.1 - 9.4e-18 64.3 0.2 2.1e-16 60.0 0.0 2.3 2 0 0 2 2 2 1 Ribosomal protein L5 Arf PF00025.21 AIN95370.1 - 2.5e-60 202.9 0.0 2.9e-60 202.7 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 AIN95370.1 - 5e-15 55.8 0.0 6.8e-15 55.3 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 AIN95370.1 - 1.7e-13 50.4 0.0 2e-13 50.2 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.22 AIN95370.1 - 8e-12 45.1 0.0 9.8e-12 44.8 0.0 1.1 1 0 0 1 1 1 1 Ras family G-alpha PF00503.20 AIN95370.1 - 5.3e-11 42.3 0.3 4.8e-08 32.5 0.0 2.3 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.12 AIN95370.1 - 5.6e-06 25.9 0.0 7.4e-06 25.5 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region 6PF2K PF01591.18 AIN95370.1 - 9.1e-05 21.9 0.0 0.00013 21.4 0.0 1.2 1 0 0 1 1 1 1 6-phosphofructo-2-kinase MMR_HSR1 PF01926.23 AIN95370.1 - 0.00025 21.1 0.0 0.00035 20.6 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase NACHT PF05729.12 AIN95370.1 - 0.014 15.4 0.2 0.13 12.2 0.2 2.0 1 1 0 1 1 1 0 NACHT domain AAA_33 PF13671.6 AIN95370.1 - 0.082 13.1 0.0 0.1 12.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 AIN95370.1 - 0.09 12.0 0.0 0.13 11.5 0.0 1.2 1 0 0 1 1 1 0 Zeta toxin SRP54 PF00448.22 AIN95370.1 - 0.22 11.1 0.2 0.34 10.5 0.2 1.2 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain Rbx_binding PF18113.1 AIN95371.1 - 0.064 13.0 0.0 0.16 11.8 0.0 1.6 1 0 0 1 1 1 0 Rubredoxin binding C-terminal domain PAP_assoc PF03828.19 AIN95372.1 - 0.00011 22.4 0.0 0.00021 21.5 0.0 1.5 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.23 AIN95372.1 - 0.00013 22.2 0.0 0.0003 21.0 0.0 1.5 1 0 0 1 1 1 1 Nucleotidyltransferase domain Polbeta PF18765.1 AIN95372.1 - 0.0051 16.9 0.0 0.0096 16.0 0.0 1.4 1 0 0 1 1 1 1 Polymerase beta, Nucleotidyltransferase Ank_2 PF12796.7 AIN95374.1 - 1.2e-20 73.8 2.7 1.5e-09 38.3 0.0 4.7 3 1 1 4 4 4 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 AIN95374.1 - 6e-20 71.4 1.0 5.8e-07 29.9 0.0 5.7 4 1 1 5 5 5 4 Ankyrin repeats (many copies) Ank PF00023.30 AIN95374.1 - 5.6e-18 64.5 6.2 2.7e-06 27.6 0.0 6.9 6 1 0 6 6 6 3 Ankyrin repeat Ank_3 PF13606.6 AIN95374.1 - 5e-16 57.2 4.8 4.6e-05 23.5 0.0 6.9 7 0 0 7 7 7 3 Ankyrin repeat DHHC PF01529.20 AIN95374.1 - 6.5e-16 58.7 1.4 6.5e-16 58.7 1.4 2.7 3 0 0 3 3 3 1 DHHC palmitoyltransferase Ank_5 PF13857.6 AIN95374.1 - 2.2e-15 56.5 8.8 1.2e-09 38.2 0.0 5.1 5 0 0 5 5 5 2 Ankyrin repeats (many copies) UCR_Fe-S_N PF10399.9 AIN95375.1 - 0.16 11.4 4.7 0.52 9.7 4.7 2.0 1 0 0 1 1 1 0 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal TPR_19 PF14559.6 AIN95376.1 - 2.7e-36 123.9 55.0 2.2e-07 31.3 1.3 16.3 9 5 8 17 17 17 10 Tetratricopeptide repeat TPR_2 PF07719.17 AIN95376.1 - 2e-28 96.1 39.0 0.00058 19.8 0.4 18.3 22 0 0 22 22 19 5 Tetratricopeptide repeat TPR_16 PF13432.6 AIN95376.1 - 5e-26 91.1 59.6 2.1e-09 37.9 3.9 13.6 13 2 2 15 15 13 7 Tetratricopeptide repeat TPR_8 PF13181.6 AIN95376.1 - 3.8e-24 82.8 15.9 0.0021 18.2 0.1 13.5 15 0 0 15 15 14 5 Tetratricopeptide repeat TPR_1 PF00515.28 AIN95376.1 - 1.4e-22 78.5 23.3 0.00025 20.7 0.7 13.0 14 0 0 14 14 14 4 Tetratricopeptide repeat TPR_14 PF13428.6 AIN95376.1 - 4.9e-19 67.4 86.7 0.00011 22.7 0.1 21.8 13 7 13 26 26 23 6 Tetratricopeptide repeat TPR_7 PF13176.6 AIN95376.1 - 7.5e-14 50.7 25.2 0.04 13.9 0.0 12.5 13 0 0 13 13 10 4 Tetratricopeptide repeat TPR_12 PF13424.6 AIN95376.1 - 1.3e-11 44.6 66.1 0.00036 20.8 0.2 16.1 14 4 2 16 16 14 5 Tetratricopeptide repeat TPR_4 PF07721.14 AIN95376.1 - 8.5e-09 35.2 40.0 0.038 14.6 0.1 13.1 12 0 0 12 12 11 2 Tetratricopeptide repeat TPR_17 PF13431.6 AIN95376.1 - 1.1e-07 31.7 12.3 0.76 10.3 0.0 10.5 11 1 0 11 11 10 1 Tetratricopeptide repeat NARP1 PF12569.8 AIN95376.1 - 1e-06 28.0 3.7 0.54 9.1 0.0 6.3 6 2 1 7 7 7 2 NMDA receptor-regulated protein 1 ANAPC3 PF12895.7 AIN95376.1 - 4.6e-06 26.8 31.6 0.082 13.1 0.6 10.0 8 2 1 9 9 9 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.6 AIN95376.1 - 4.8e-06 26.9 67.2 1.3 9.8 0.0 19.0 22 0 0 22 22 19 2 Tetratricopeptide repeat TPR_11 PF13414.6 AIN95376.1 - 5.6e-06 25.9 21.3 2.6 7.8 0.0 10.4 13 0 0 13 13 13 4 TPR repeat TPR_15 PF13429.6 AIN95376.1 - 3.7e-05 23.1 33.8 0.0022 17.3 1.2 7.3 6 2 1 7 7 7 2 Tetratricopeptide repeat TPR_10 PF13374.6 AIN95376.1 - 9.5e-05 22.1 36.1 0.057 13.3 0.0 11.6 12 0 0 12 12 11 2 Tetratricopeptide repeat HrpB1_HrpK PF09613.10 AIN95376.1 - 0.00011 21.8 24.2 0.038 13.6 0.9 7.3 7 3 1 8 8 7 2 Bacterial type III secretion protein (HrpB1_HrpK) PPR PF01535.20 AIN95376.1 - 0.013 15.7 2.0 1.9 8.9 0.0 5.0 5 0 0 5 5 3 0 PPR repeat SNAP PF14938.6 AIN95376.1 - 0.036 13.5 20.7 1.2 8.5 4.3 5.8 5 1 0 6 6 6 0 Soluble NSF attachment protein, SNAP MIT PF04212.18 AIN95376.1 - 0.13 12.4 5.5 20 5.4 0.1 4.6 4 0 0 4 4 3 0 MIT (microtubule interacting and transport) domain Coatomer_E PF04733.14 AIN95376.1 - 0.23 10.8 4.7 7.3 5.9 0.0 3.9 4 0 0 4 4 4 0 Coatomer epsilon subunit ChAPs PF09295.10 AIN95376.1 - 1.4 7.8 6.8 0.4 9.6 0.1 2.9 4 0 0 4 4 4 0 ChAPs (Chs5p-Arf1p-binding proteins) TPR_21 PF09976.9 AIN95376.1 - 6.9 6.3 43.2 0.11 12.1 3.0 8.4 7 3 2 9 9 8 0 Tetratricopeptide repeat-like domain Y_phosphatase2 PF03162.13 AIN95377.1 - 1e-51 174.8 0.0 1.4e-51 174.4 0.0 1.1 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3 PF13350.6 AIN95377.1 - 1.1e-09 38.7 0.0 1.3e-09 38.3 0.0 1.2 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase PF00102.27 AIN95377.1 - 0.0084 15.7 0.0 0.011 15.4 0.0 1.1 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.20 AIN95377.1 - 0.047 13.5 0.0 0.065 13.0 0.0 1.3 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.6 AIN95377.1 - 0.2 11.8 0.0 0.3 11.2 0.0 1.2 1 0 0 1 1 1 0 Inositol hexakisphosphate DENN PF02141.21 AIN95378.1 - 1.4e-08 34.9 0.3 4e-08 33.4 0.3 1.7 1 0 0 1 1 1 1 DENN (AEX-3) domain Spermine_synth PF01564.17 AIN95379.1 - 2.8e-48 163.8 0.0 5.2e-48 163.0 0.0 1.4 2 0 0 2 2 2 1 Spermine/spermidine synthase domain Spermine_synt_N PF17284.2 AIN95379.1 - 1.6e-15 56.7 0.0 2.9e-15 55.9 0.0 1.4 1 0 0 1 1 1 1 Spermidine synthase tetramerisation domain Methyltransf_25 PF13649.6 AIN95379.1 - 3.2e-05 24.6 0.0 5.9e-05 23.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 AIN95379.1 - 0.0054 17.4 0.0 0.052 14.3 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 AIN95379.1 - 0.073 13.7 0.1 0.22 12.2 0.1 1.8 1 1 0 1 1 1 0 Methyltransferase domain CRM1_repeat_2 PF18784.1 AIN95379.1 - 0.09 12.4 0.1 0.28 10.8 0.0 1.9 2 0 0 2 2 2 0 CRM1 / Exportin repeat 2 DUF1616 PF07760.11 AIN95380.1 - 0.018 14.5 0.2 0.027 13.8 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1616) DUF2207 PF09972.9 AIN95380.1 - 0.045 12.5 0.0 0.086 11.6 0.0 1.3 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF1168 PF06658.12 AIN95381.1 - 6e-05 22.9 13.9 7.2e-05 22.6 13.9 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1168) DUF755 PF05501.11 AIN95381.1 - 0.0024 18.1 14.2 0.0024 18.1 14.2 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF755) Cwf_Cwc_15 PF04889.12 AIN95381.1 - 0.005 16.6 12.7 0.0057 16.4 12.7 1.2 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein AF-4 PF05110.13 AIN95381.1 - 0.015 13.4 12.8 0.022 12.9 12.8 1.3 1 0 0 1 1 1 0 AF-4 proto-oncoprotein Cu-oxidase_4 PF02578.15 AIN95381.1 - 0.03 13.9 0.4 0.037 13.6 0.4 1.1 1 0 0 1 1 1 0 Multi-copper polyphenol oxidoreductase laccase DUF3482 PF11981.8 AIN95381.1 - 0.46 9.8 9.7 0.64 9.4 9.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3482) DUF4692 PF15763.5 AIN95381.1 - 0.47 10.9 8.1 0.91 10.0 8.1 1.5 1 0 0 1 1 1 0 Regulator of human erythroid cell expansion (RHEX) DUF4603 PF15376.6 AIN95381.1 - 0.68 7.3 11.3 0.84 6.9 11.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4603) GREB1 PF15782.5 AIN95381.1 - 0.74 6.9 6.2 0.69 7.0 6.2 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer AKNA PF12443.8 AIN95381.1 - 0.78 10.4 10.2 5.8 7.6 9.1 2.2 2 0 0 2 2 2 0 AT-hook-containing transcription factor DUF1003 PF06210.11 AIN95381.1 - 3.8 7.7 6.0 6.8 6.8 5.7 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1003) U1snRNP70_N PF12220.8 AIN95381.1 - 4.2 8.1 12.8 17 6.1 12.8 2.0 1 1 0 1 1 1 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal FAM60A PF15396.6 AIN95381.1 - 7 6.6 12.4 6.9 6.6 11.6 1.4 1 1 0 1 1 1 0 Protein Family FAM60A TFIID-18kDa PF02269.16 AIN95384.1 - 0.052 13.6 0.5 0.097 12.7 0.5 1.5 1 0 0 1 1 1 0 Transcription initiation factor IID, 18kD subunit Pox_EPC_I2-L1 PF12575.8 AIN95384.1 - 0.27 11.5 1.7 59 4.0 0.1 3.1 3 0 0 3 3 3 0 Poxvirus entry protein complex L1 and I2 zf-C3HC4_3 PF13920.6 AIN95385.1 - 1e-08 34.9 9.9 2e-08 34.0 9.9 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 AIN95385.1 - 2.8e-07 30.3 10.0 5.4e-07 29.4 10.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 AIN95385.1 - 8.8e-06 26.0 13.5 1.9e-05 24.9 13.5 1.6 1 0 0 1 1 1 1 Ring finger domain Prok-RING_4 PF14447.6 AIN95385.1 - 0.0026 17.6 10.8 0.0054 16.6 10.8 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 AIN95385.1 - 0.013 15.4 12.5 0.035 13.9 12.5 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 AIN95385.1 - 0.025 14.6 9.8 0.063 13.3 9.8 1.8 1 1 0 1 1 1 0 RING-type zinc-finger DUF1449 PF07290.11 AIN95385.1 - 0.03 14.0 0.1 0.03 14.0 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1449) Baculo_IE-1 PF05290.11 AIN95385.1 - 0.23 11.4 3.9 0.4 10.6 3.9 1.3 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) zf-RING_4 PF14570.6 AIN95385.1 - 0.67 9.8 8.5 1.5 8.7 8.5 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain RskA PF10099.9 AIN95385.1 - 6.5 7.0 11.5 2.6 8.3 1.7 2.2 2 0 0 2 2 2 0 Anti-sigma-K factor rskA Pkinase PF00069.25 AIN95386.1 - 2.4e-38 132.0 0.0 3.7e-17 62.6 0.1 6.0 5 1 0 5 5 5 4 Protein kinase domain Pkinase_Tyr PF07714.17 AIN95386.1 - 9.3e-15 54.6 0.0 1.5e-08 34.3 0.2 4.1 4 0 0 4 4 4 3 Protein tyrosine kinase FHA PF00498.26 AIN95386.1 - 2.9e-07 30.7 0.0 1.7e-06 28.3 0.0 2.1 1 1 0 1 1 1 1 FHA domain Pkinase_fungal PF17667.1 AIN95386.1 - 0.12 11.2 0.3 0.23 10.2 0.0 1.6 2 0 0 2 2 2 0 Fungal protein kinase DUF2076 PF09849.9 AIN95387.1 - 5.1e-06 26.7 9.7 6.7e-06 26.3 9.7 1.2 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2076) CHCH PF06747.13 AIN95387.1 - 0.00031 20.8 1.2 0.00044 20.3 1.2 1.2 1 0 0 1 1 1 1 CHCH domain CX9C PF16860.5 AIN95387.1 - 0.0033 17.4 0.5 0.0054 16.7 0.5 1.3 1 0 0 1 1 1 1 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, UQ_con PF00179.26 AIN95388.1 - 8.7e-46 155.0 0.0 9.8e-46 154.9 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UEV PF05743.13 AIN95388.1 - 0.0063 16.4 0.2 0.013 15.4 0.2 1.5 1 1 0 1 1 1 1 UEV domain Prok-E2_B PF14461.6 AIN95388.1 - 0.011 15.4 0.0 0.014 15.1 0.0 1.2 1 0 0 1 1 1 0 Prokaryotic E2 family B Ax_dynein_light PF10211.9 AIN95389.1 - 7.6e-10 39.0 3.8 7.6e-10 39.0 3.8 2.6 4 0 0 4 4 4 1 Axonemal dynein light chain CesT PF05932.13 AIN95391.1 - 1.6e-09 37.9 0.0 3.6e-09 36.8 0.0 1.7 1 0 0 1 1 1 1 Tir chaperone protein (CesT) family PDZ_2 PF13180.6 AIN95391.1 - 6.3e-08 32.8 0.0 1.5e-06 28.4 0.1 2.4 2 0 0 2 2 2 1 PDZ domain PDZ_6 PF17820.1 AIN95391.1 - 1.5e-05 24.8 0.2 0.00015 21.6 0.1 2.6 2 0 0 2 2 2 1 PDZ domain DUF974 PF06159.13 AIN95393.1 - 4.3e-06 26.7 0.0 1.2e-05 25.2 0.0 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF974) WASH_WAHD PF11945.8 AIN95394.1 - 6.9e-07 29.1 0.0 1.2e-06 28.3 0.0 1.3 1 0 0 1 1 1 1 WAHD domain of WASH complex XRCC4 PF06632.12 AIN95394.1 - 0.33 9.7 3.8 0.62 8.9 3.8 1.3 1 0 0 1 1 1 0 DNA double-strand break repair and V(D)J recombination protein XRCC4 Ribosomal_L16 PF00252.18 AIN95395.1 - 1.2e-39 135.3 0.3 1.6e-39 135.0 0.3 1.1 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e DUF1490 PF07371.12 AIN95395.1 - 0.011 15.8 0.2 0.059 13.4 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1490) DUF3212 PF11486.8 AIN95395.1 - 0.14 12.2 0.0 0.21 11.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3212) zf-TRM13_CCCH PF11722.8 AIN95395.1 - 0.48 10.2 10.0 11 5.8 0.0 2.4 2 0 0 2 2 2 0 CCCH zinc finger in TRM13 protein NAC PF01849.18 AIN95396.1 - 2.1e-13 50.0 0.2 2.1e-13 50.0 0.2 2.0 2 0 0 2 2 2 1 NAC domain DUF3246 PF11596.8 AIN95396.1 - 0.0096 15.4 1.2 0.012 15.0 1.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3246) Myc_N PF01056.18 AIN95396.1 - 0.029 14.3 2.1 0.032 14.1 2.1 1.1 1 0 0 1 1 1 0 Myc amino-terminal region PGA2 PF07543.12 AIN95396.1 - 0.087 12.8 3.0 0.57 10.2 0.8 2.0 2 0 0 2 2 2 0 Protein trafficking PGA2 DnaJ PF00226.31 AIN95397.1 - 1.5e-18 66.7 0.1 2.2e-18 66.1 0.1 1.3 1 0 0 1 1 1 1 DnaJ domain Tmemb_185A PF10269.9 AIN95397.1 - 1.1e-09 38.4 2.1 3.4e-09 36.8 0.5 2.6 1 1 1 2 2 2 2 Transmembrane Fragile-X-F protein Pescadillo_N PF06732.11 AIN95400.1 - 2e-90 303.1 4.2 5.2e-90 301.7 4.2 1.6 1 0 0 1 1 1 1 Pescadillo N-terminus BRCT_2 PF16589.5 AIN95400.1 - 8.1e-11 42.2 0.0 1.8e-10 41.1 0.0 1.6 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain LIG3_BRCT PF16759.5 AIN95400.1 - 2.5e-06 27.7 0.0 7.2e-06 26.2 0.0 1.8 1 0 0 1 1 1 1 DNA ligase 3 BRCT domain BRCT PF00533.26 AIN95400.1 - 0.0001 22.6 0.0 0.00027 21.3 0.0 1.8 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain Pep_deformylase PF01327.21 AIN95401.1 - 2.3e-16 59.8 0.0 2.4e-15 56.5 0.0 2.3 1 1 0 1 1 1 1 Polypeptide deformylase Y_phosphatase2 PF03162.13 AIN95403.1 - 7e-53 178.6 0.0 9.3e-53 178.2 0.0 1.1 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3 PF13350.6 AIN95403.1 - 0.004 17.1 0.0 0.0064 16.5 0.0 1.2 1 0 0 1 1 1 1 Tyrosine phosphatase family Rhomboid PF01694.22 AIN95404.1 - 1.4e-08 34.9 1.9 2.8e-08 33.9 1.9 1.5 1 0 0 1 1 1 1 Rhomboid family DuoxA PF10204.9 AIN95404.1 - 0.23 10.5 3.5 0.053 12.5 0.4 1.4 2 0 0 2 2 2 0 Dual oxidase maturation factor Ribosomal_L30 PF00327.20 AIN95405.1 - 4.1e-05 23.4 0.5 0.00016 21.4 0.0 2.1 2 0 0 2 2 2 1 Ribosomal protein L30p/L7e TPR_8 PF13181.6 AIN95408.1 - 3.7e-05 23.6 0.6 0.00086 19.3 0.1 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat IQ PF00612.27 AIN95408.1 - 0.0017 18.0 0.5 0.0054 16.4 0.5 1.9 1 0 0 1 1 1 1 IQ calmodulin-binding motif TPR_12 PF13424.6 AIN95408.1 - 0.0074 16.5 2.1 0.83 10.0 0.0 2.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.17 AIN95408.1 - 0.008 16.2 0.4 0.045 13.9 0.0 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_21 PF09976.9 AIN95408.1 - 0.012 15.3 0.0 0.032 13.9 0.0 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat-like domain TPR_11 PF13414.6 AIN95408.1 - 0.033 13.9 0.3 0.094 12.4 0.3 1.8 1 0 0 1 1 1 0 TPR repeat TPR_1 PF00515.28 AIN95408.1 - 0.064 13.1 1.6 0.09 12.6 0.1 1.9 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF1840 PF08895.11 AIN95410.1 - 0.59 10.5 4.4 0.26 11.7 0.7 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1840) Zip PF02535.22 AIN95410.1 - 1.1 8.4 3.9 0.36 10.0 0.2 1.8 2 0 0 2 2 2 0 ZIP Zinc transporter Cmc1 PF08583.10 AIN95411.1 - 0.00077 19.4 1.8 0.0011 18.9 1.8 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like Ndufs5 PF10200.9 AIN95411.1 - 0.024 14.9 0.3 0.034 14.4 0.3 1.3 1 0 0 1 1 1 0 NADH:ubiquinone oxidoreductase, NDUFS5-15kDa DnaJ_C PF01556.18 AIN95412.1 - 2.1e-35 122.0 0.1 2.9e-35 121.5 0.1 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 AIN95412.1 - 3.3e-21 75.2 0.7 6.4e-21 74.3 0.4 1.6 2 0 0 2 2 2 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 AIN95412.1 - 4.9e-08 33.2 23.4 1e-07 32.2 23.4 1.6 1 0 0 1 1 1 1 DnaJ central domain Anti-TRAP PF15777.5 AIN95412.1 - 0.74 9.8 22.3 0.51 10.3 3.8 2.7 1 1 1 2 2 2 0 Tryptophan RNA-binding attenuator protein inhibitory protein Ribosomal_L16 PF00252.18 AIN95413.1 - 1.2e-39 135.3 0.3 1.6e-39 135.0 0.3 1.1 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e DUF1490 PF07371.12 AIN95413.1 - 0.011 15.8 0.2 0.059 13.4 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1490) DUF3212 PF11486.8 AIN95413.1 - 0.14 12.2 0.0 0.21 11.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3212) zf-TRM13_CCCH PF11722.8 AIN95413.1 - 0.48 10.2 10.0 11 5.8 0.0 2.4 2 0 0 2 2 2 0 CCCH zinc finger in TRM13 protein ADK PF00406.22 AIN95414.1 - 1.1e-38 132.7 0.0 1.3e-38 132.4 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 AIN95414.1 - 1.5e-28 99.9 0.0 1.9e-28 99.6 0.0 1.1 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 AIN95414.1 - 4e-06 27.4 0.0 7.7e-06 26.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 AIN95414.1 - 3.4e-05 24.0 0.0 0.00013 22.1 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.6 AIN95414.1 - 0.011 16.0 0.2 0.024 14.9 0.1 1.9 1 1 0 1 1 1 0 AAA domain dNK PF01712.19 AIN95414.1 - 0.033 14.0 0.3 0.2 11.5 0.1 1.9 2 0 0 2 2 2 0 Deoxynucleoside kinase Cytidylate_kin PF02224.18 AIN95414.1 - 0.073 12.8 0.1 0.24 11.1 0.0 1.9 2 0 0 2 2 2 0 Cytidylate kinase AAA_22 PF13401.6 AIN95414.1 - 0.16 12.2 0.0 0.94 9.7 0.0 2.0 1 1 0 1 1 1 0 AAA domain SRP54 PF00448.22 AIN95414.1 - 0.17 11.5 0.0 0.25 11.0 0.0 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_19 PF13245.6 AIN95414.1 - 0.18 12.2 0.0 0.31 11.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain FYVE PF01363.21 AIN95416.1 - 1.9 8.7 4.9 0.24 11.6 0.4 1.8 2 0 0 2 2 2 0 FYVE zinc finger DZR PF12773.7 AIN95416.1 - 7.4 6.7 11.6 2.5 8.2 1.7 3.0 3 0 0 3 3 3 0 Double zinc ribbon SDA1 PF05285.12 AIN95418.1 - 0.00011 21.8 20.0 0.00012 21.6 20.0 1.2 1 0 0 1 1 1 1 SDA1 Nop14 PF04147.12 AIN95418.1 - 0.00014 20.3 23.0 0.00023 19.6 23.0 1.3 1 0 0 1 1 1 1 Nop14-like family YL1 PF05764.13 AIN95418.1 - 0.00022 21.5 20.4 0.00031 20.9 20.4 1.3 1 0 0 1 1 1 1 YL1 nuclear protein CDC45 PF02724.14 AIN95418.1 - 0.0024 16.2 15.8 0.0029 16.0 15.8 1.1 1 0 0 1 1 1 1 CDC45-like protein TFIIF_alpha PF05793.12 AIN95418.1 - 0.0041 15.8 21.3 0.0051 15.5 21.3 1.2 1 0 0 1 1 1 1 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Mpp10 PF04006.12 AIN95418.1 - 0.038 12.4 18.5 0.053 12.0 18.5 1.2 1 0 0 1 1 1 0 Mpp10 protein DNA_pol_phi PF04931.13 AIN95418.1 - 0.21 9.7 30.2 0.29 9.2 30.2 1.3 1 0 0 1 1 1 0 DNA polymerase phi DUF913 PF06025.12 AIN95418.1 - 0.24 10.3 2.8 0.39 9.7 2.8 1.4 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Zip PF02535.22 AIN95418.1 - 0.62 9.2 2.3 0.71 9.0 2.3 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter SAPS PF04499.15 AIN95418.1 - 2.4 6.9 7.1 3.3 6.4 7.1 1.3 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein BUD22 PF09073.10 AIN95418.1 - 5.7 6.2 29.1 8.7 5.6 29.1 1.2 1 0 0 1 1 1 0 BUD22 Voltage_CLC PF00654.20 AIN95419.1 - 9.7e-88 294.8 24.8 9.7e-88 294.8 24.8 1.7 2 0 0 2 2 2 1 Voltage gated chloride channel CBS PF00571.28 AIN95419.1 - 5.1e-06 26.8 3.1 0.06 13.8 0.0 3.6 3 0 0 3 3 3 2 CBS domain TAT_signal PF10518.9 AIN95419.1 - 0.39 10.6 5.9 0.098 12.5 0.4 2.7 2 0 0 2 2 2 0 TAT (twin-arginine translocation) pathway signal sequence RRP36 PF06102.12 AIN95420.1 - 6.9e-30 104.2 7.9 1.7e-29 102.9 7.9 1.6 1 1 0 1 1 1 1 rRNA biogenesis protein RRP36 DUF1660 PF07874.11 AIN95420.1 - 0.15 12.5 1.3 0.3 11.6 1.3 1.4 1 0 0 1 1 1 0 Prophage protein (DUF1660) COPI_assoc PF08507.10 AIN95421.1 - 4.1e-13 49.5 8.7 5.9e-13 49.0 8.7 1.2 1 0 0 1 1 1 1 COPI associated protein NICE-1 PF15845.5 AIN95421.1 - 0.64 10.8 4.0 1.2 9.9 4.0 1.4 1 0 0 1 1 1 0 Cysteine-rich C-terminal 1 family Acyltransferase PF01553.21 AIN95422.1 - 2e-13 50.1 0.0 3.5e-13 49.3 0.0 1.4 1 0 0 1 1 1 1 Acyltransferase Acyltransferase PF01553.21 AIN95423.1 - 4.7e-12 45.7 0.0 9.4e-12 44.7 0.0 1.5 1 0 0 1 1 1 1 Acyltransferase DUF3486 PF11985.8 AIN95423.1 - 0.071 13.5 3.3 0.14 12.5 3.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3486) ISAV_HA PF06215.11 AIN95425.1 - 0.16 11.1 0.0 0.19 10.8 0.0 1.1 1 0 0 1 1 1 0 Infectious salmon anaemia virus haemagglutinin Tcf25 PF04910.14 AIN95426.1 - 3.3e-36 125.1 0.0 5.2e-36 124.4 0.0 1.2 1 0 0 1 1 1 1 Transcriptional repressor TCF25 eIF3_subunit PF08597.10 AIN95426.1 - 7.8 6.3 19.1 18 5.2 19.1 1.5 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit RICTOR_phospho PF14665.6 AIN95427.1 - 0.01 16.1 2.1 0.039 14.3 2.1 2.0 1 0 0 1 1 1 0 Rapamycin-insensitive companion of mTOR, phosphorylation-site UpxZ PF06603.11 AIN95427.1 - 0.67 10.3 4.5 0.39 11.0 1.5 2.2 2 0 0 2 2 2 0 UpxZ family of transcription anti-terminator antagonists DUF5446 PF17522.2 AIN95427.1 - 2.1 8.6 5.9 0.61 10.3 0.5 3.0 2 0 0 2 2 2 0 Family of unknown function (DUF5446) Transglut_i_TM PF14400.6 AIN95429.1 - 0.59 10.2 7.1 0.19 11.8 2.6 2.3 1 1 0 2 2 2 0 Inactive transglutaminase fused to 7 transmembrane helices DUF1664 PF07889.12 AIN95429.1 - 7.8 6.6 11.6 0.19 11.7 2.9 2.4 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) SCO1-SenC PF02630.14 AIN95430.1 - 1.6e-44 151.1 0.0 2.4e-44 150.5 0.0 1.3 1 0 0 1 1 1 1 SCO1/SenC AhpC-TSA PF00578.21 AIN95430.1 - 0.13 12.2 0.0 0.29 11.1 0.0 1.7 1 0 0 1 1 1 0 AhpC/TSA family Phage_T4_Ndd PF06591.11 AIN95432.1 - 0.032 14.0 0.0 0.045 13.5 0.0 1.1 1 0 0 1 1 1 0 T4-like phage nuclear disruption protein (Ndd) FBPase PF00316.20 AIN95433.1 - 2e-58 197.0 0.0 2.5e-58 196.7 0.0 1.1 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase, N-terminal domain Methyltransf_21 PF05050.12 AIN95434.1 - 4e-11 43.2 0.0 1.3e-09 38.4 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase FkbM domain Methyltransf_12 PF08242.12 AIN95434.1 - 0.14 12.9 0.0 0.32 11.8 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_25 PF13649.6 AIN95434.1 - 0.15 12.8 0.0 0.34 11.6 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.14 AIN95434.1 - 0.15 11.6 0.0 0.25 10.9 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain RRM_1 PF00076.22 AIN95435.1 - 2.5e-13 49.6 0.0 1.4e-05 24.8 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 AIN95435.1 - 7.4e-09 35.3 0.1 0.00051 19.6 0.1 2.4 1 1 1 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 AIN95435.1 - 0.00025 20.8 0.2 0.0042 16.9 0.1 2.5 2 1 0 2 2 2 1 Occluded RNA-recognition motif CDC48_2 PF02933.17 AIN95435.1 - 0.0021 17.8 0.0 0.0045 16.7 0.0 1.6 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), domain 2 RRM_8 PF11835.8 AIN95435.1 - 0.004 17.3 0.1 0.013 15.7 0.1 1.9 2 0 0 2 2 2 1 RRM-like domain DUF5399 PF17377.2 AIN95435.1 - 0.044 13.6 0.5 0.12 12.2 0.1 1.9 2 0 0 2 2 2 0 Family of unknown function (DUF5399) DUF2857 PF11198.8 AIN95436.1 - 0.68 9.7 4.7 0.37 10.5 2.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2857) CorA PF01544.18 AIN95436.1 - 3.3 6.9 5.5 8.7 5.6 0.7 2.5 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein PolyA_pol PF01743.20 AIN95437.1 - 8.4e-29 100.6 0.0 1.9e-28 99.4 0.0 1.6 1 0 0 1 1 1 1 Poly A polymerase head domain PolyA_pol_RNAbd PF12627.7 AIN95437.1 - 3.1e-07 30.0 0.1 7.7e-07 28.8 0.1 1.6 1 0 0 1 1 1 1 Probable RNA and SrmB- binding site of polymerase A Tenui_N PF05733.11 AIN95437.1 - 0.19 11.2 0.1 0.35 10.4 0.1 1.3 1 0 0 1 1 1 0 Tenuivirus/Phlebovirus nucleocapsid protein LRR_6 PF13516.6 AIN95438.1 - 2.7e-05 23.9 0.0 1.4 9.2 0.0 3.9 4 0 0 4 4 4 2 Leucine Rich repeat LRR_8 PF13855.6 AIN95438.1 - 0.057 13.2 0.6 2.9 7.7 0.2 3.4 3 1 1 4 4 4 0 Leucine rich repeat LRR_4 PF12799.7 AIN95438.1 - 0.076 13.5 0.3 2.3 8.8 0.1 3.0 2 1 1 3 3 3 0 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 AIN95438.1 - 0.076 13.6 0.0 1.1e+02 4.0 0.0 3.4 3 0 0 3 3 3 0 Leucine Rich Repeat Pkinase PF00069.25 AIN95439.1 - 4.1e-26 91.9 0.0 5.1e-26 91.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 AIN95439.1 - 2.3e-16 59.9 0.1 3.7e-16 59.2 0.1 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 AIN95439.1 - 8.2e-07 28.1 0.1 1e-06 27.8 0.1 1.1 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 AIN95439.1 - 0.0026 17.2 0.0 0.0044 16.4 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 AIN95439.1 - 0.087 12.7 0.0 0.15 12.0 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Haspin_kinase PF12330.8 AIN95439.1 - 0.14 11.1 0.0 0.22 10.5 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain Gelsolin PF00626.22 AIN95440.1 - 0.64 10.0 4.2 0.18 11.7 0.2 2.2 2 0 0 2 2 2 0 Gelsolin repeat IBP39 PF11422.8 AIN95440.1 - 0.84 9.4 4.8 1.7 8.3 4.8 1.4 1 0 0 1 1 1 0 Initiator binding protein 39 kDa Actin PF00022.19 AIN95441.1 - 2.2e-142 474.5 0.0 1.9e-141 471.4 0.0 1.9 1 1 0 1 1 1 1 Actin Macoilin PF09726.9 AIN95442.1 - 0.0014 17.3 22.2 0.0014 17.3 22.2 5.7 1 1 3 5 5 5 1 Macoilin family BLOC1_2 PF10046.9 AIN95442.1 - 0.0056 17.0 1.9 0.0056 17.0 1.9 9.9 5 2 3 10 10 10 3 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF3502 PF12010.8 AIN95442.1 - 0.17 12.5 5.3 0.28 11.8 0.7 3.3 3 1 1 4 4 4 0 Domain of unknown function (DUF3502) Arf PF00025.21 AIN95444.1 - 3.9e-54 182.7 0.0 4.4e-54 182.6 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.20 AIN95444.1 - 2.7e-09 36.6 1.0 1.9e-06 27.3 0.0 2.7 1 1 1 2 2 2 2 G-protein alpha subunit SRPRB PF09439.10 AIN95444.1 - 1.3e-08 34.5 0.0 1.7e-08 34.2 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Roc PF08477.13 AIN95444.1 - 2e-08 34.5 0.0 5.8e-08 33.0 0.0 1.7 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 AIN95444.1 - 2.3e-08 34.1 0.0 4.8e-08 33.1 0.0 1.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase Ras PF00071.22 AIN95444.1 - 5.1e-08 32.7 0.0 6.8e-08 32.3 0.0 1.2 1 0 0 1 1 1 1 Ras family GTP_EFTU PF00009.27 AIN95444.1 - 3.4e-05 23.5 0.2 0.011 15.2 0.0 2.1 1 1 1 2 2 2 2 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 AIN95444.1 - 6e-05 22.5 0.0 8.1e-05 22.1 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region cobW PF02492.19 AIN95444.1 - 0.011 15.3 0.1 0.82 9.2 0.0 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain FeoB_N PF02421.18 AIN95444.1 - 0.039 13.5 0.1 0.22 11.1 0.1 2.0 1 1 0 1 1 1 0 Ferrous iron transport protein B SRP54 PF00448.22 AIN95444.1 - 0.15 11.7 0.2 0.15 11.7 0.2 1.9 3 0 0 3 3 3 0 SRP54-type protein, GTPase domain WD40_alt PF14077.6 AIN95445.1 - 1.6 8.7 5.3 9.1 6.2 0.0 4.0 3 0 0 3 3 3 0 Alternative WD40 repeat motif ROQ_II PF18386.1 AIN95445.1 - 7.3 6.5 6.7 1.9 8.4 1.9 2.6 2 0 0 2 2 2 0 Roquin II domain DUF1664 PF07889.12 AIN95446.1 - 0.013 15.6 2.2 0.013 15.6 2.2 4.9 5 0 0 5 5 5 0 Protein of unknown function (DUF1664) DUF1878 PF08963.10 AIN95446.1 - 1.8 9.1 9.1 0.07 13.6 0.7 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF1878) Vault PF01505.18 AIN95447.1 - 1.1e-50 169.5 1.7 1.4e-12 47.5 0.1 5.0 4 0 0 4 4 4 4 Major Vault Protein repeat domain MVP_shoulder PF11978.8 AIN95447.1 - 7.9e-47 158.2 0.2 1.6e-46 157.2 0.2 1.5 1 0 0 1 1 1 1 Shoulder domain Vault_3 PF17795.1 AIN95447.1 - 9e-32 108.9 1.7 3.3e-30 103.9 0.1 3.5 3 0 0 3 3 3 1 Major Vault Protein Repeat domain Vault_2 PF17794.1 AIN95447.1 - 4.6e-28 97.4 1.2 5e-21 74.8 0.1 3.4 4 0 0 4 4 4 2 Major Vault Protein repeat domain Vault_4 PF17796.1 AIN95447.1 - 6.9e-21 74.1 0.1 3e-19 68.8 0.1 3.2 3 0 0 3 3 3 1 Major Vault Protein repeat domain NfeD PF01957.18 AIN95447.1 - 0.0018 18.6 2.3 4.3 7.8 0.0 4.5 4 1 1 5 5 5 1 NfeD-like C-terminal, partner-binding DUF3601 PF12208.8 AIN95447.1 - 0.014 15.4 0.0 4.7 7.4 0.0 3.4 2 1 1 3 3 3 0 Domain of unknown function (DUF3601) Dynein_light PF01221.18 AIN95448.1 - 3e-29 101.2 0.8 3.5e-29 101.0 0.8 1.1 1 0 0 1 1 1 1 Dynein light chain type 1 Vasohibin PF14822.6 AIN95448.1 - 0.0077 15.5 0.1 0.011 15.0 0.1 1.4 1 1 1 2 2 2 1 Vasohibin CBM_48 PF02922.18 AIN95448.1 - 0.1 12.9 0.0 0.13 12.6 0.0 1.2 1 0 0 1 1 1 0 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) Rrp15p PF07890.12 AIN95449.1 - 4.2e-10 40.1 10.7 1e-09 38.8 10.7 1.6 1 1 0 1 1 1 1 Rrp15p NUDIX PF00293.28 AIN95450.1 - 1.9e-15 57.1 0.0 2.9e-15 56.5 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain Metallophos PF00149.28 AIN95451.1 - 4.2e-26 92.7 0.1 6.9e-26 92.0 0.1 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Plus-3 PF03126.18 AIN95451.1 - 7.9e-06 26.4 0.0 1.5e-05 25.5 0.0 1.5 1 0 0 1 1 1 1 Plus-3 domain Methyltransf_4 PF02390.17 AIN95453.1 - 0.0027 17.2 0.0 0.0041 16.6 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase Pkinase PF00069.25 AIN95454.1 - 2.1e-54 184.7 0.0 3.3e-54 184.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 AIN95454.1 - 1.3e-28 100.0 0.1 5e-26 91.5 0.1 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 AIN95454.1 - 7.9e-06 24.9 0.0 1e-05 24.5 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 AIN95454.1 - 0.00098 19.1 0.0 0.0042 17.0 0.0 1.8 1 1 1 2 2 2 1 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.9 AIN95454.1 - 0.0041 16.7 0.5 0.0097 15.4 0.5 1.5 1 1 0 1 1 1 1 PhoP regulatory network protein YrbL RIO1 PF01163.22 AIN95454.1 - 0.029 14.0 1.0 0.06 12.9 1.0 1.5 1 1 0 1 1 1 0 RIO1 family Haspin_kinase PF12330.8 AIN95454.1 - 0.042 12.8 0.3 0.066 12.2 0.3 1.2 1 0 0 1 1 1 0 Haspin like kinase domain 6PGD PF00393.19 AIN95454.1 - 0.076 12.4 0.0 0.13 11.6 0.0 1.4 1 0 0 1 1 1 0 6-phosphogluconate dehydrogenase, C-terminal domain Kinase-PolyVal PF18762.1 AIN95454.1 - 0.086 12.8 0.5 0.19 11.7 0.5 1.6 1 1 0 1 1 1 0 Serine/Threonine/Tyrosine Kinase found in polyvalent proteins DEAD PF00270.29 AIN95455.1 - 5e-42 143.6 0.0 9.9e-42 142.7 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 AIN95455.1 - 2.2e-31 108.5 0.0 2.2e-28 98.8 0.0 3.2 3 0 0 3 3 3 2 Helicase conserved C-terminal domain GUCT PF08152.12 AIN95455.1 - 3.7e-19 68.8 0.0 1e-18 67.4 0.0 1.8 1 0 0 1 1 1 1 GUCT (NUC152) domain ERCC3_RAD25_C PF16203.5 AIN95455.1 - 8.1e-05 22.0 0.0 0.00017 20.9 0.0 1.5 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase ResIII PF04851.15 AIN95455.1 - 0.015 15.3 0.3 0.043 13.8 0.0 1.9 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit LRR_6 PF13516.6 AIN95456.1 - 1.1e-39 131.1 21.0 1.4e-06 27.9 0.2 10.6 11 0 0 11 11 11 8 Leucine Rich repeat LRR_4 PF12799.7 AIN95456.1 - 9e-10 38.7 4.4 3.7e-05 24.0 0.0 5.0 5 2 1 6 6 6 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 AIN95456.1 - 2.6e-08 33.3 0.0 4.9 8.1 0.0 7.1 7 0 0 7 7 7 1 Leucine Rich Repeat LRR_8 PF13855.6 AIN95456.1 - 1.4e-06 28.0 8.4 0.14 12.0 0.1 5.8 4 2 1 5 5 5 3 Leucine rich repeat IFRD PF05004.13 AIN95456.1 - 0.003 16.7 0.5 0.0043 16.2 0.5 1.1 1 0 0 1 1 1 1 Interferon-related developmental regulator (IFRD) FIVAR PF07554.13 AIN95457.1 - 0.027 15.2 8.5 0.93 10.3 2.3 3.6 2 1 1 3 3 3 0 FIVAR domain DUF812 PF05667.11 AIN95457.1 - 5.2 5.8 35.7 3.8 6.3 17.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF812) Spc7 PF08317.11 AIN95457.1 - 7 5.4 47.2 0.0086 15.0 12.2 3.3 2 1 1 3 3 3 0 Spc7 kinetochore protein 2-oxoacid_dh PF00198.23 AIN95459.1 - 9.4e-78 260.9 0.0 1.2e-77 260.5 0.0 1.1 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 AIN95459.1 - 5e-17 61.5 1.3 7.5e-17 60.9 0.4 1.8 2 0 0 2 2 2 1 Biotin-requiring enzyme E3_binding PF02817.17 AIN95459.1 - 3.3e-13 49.7 0.2 8.4e-13 48.4 0.2 1.8 1 0 0 1 1 1 1 e3 binding domain HlyD_3 PF13437.6 AIN95459.1 - 0.19 12.5 0.7 1.1 10.0 0.1 2.5 3 0 0 3 3 3 0 HlyD family secretion protein Fip1 PF05182.13 AIN95460.1 - 1e-17 63.4 0.5 1.6e-17 62.7 0.5 1.3 1 0 0 1 1 1 1 Fip1 motif zf-CCCH PF00642.24 AIN95460.1 - 4e-09 36.2 3.6 7.4e-09 35.3 3.6 1.5 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 AIN95460.1 - 0.00089 19.0 4.4 0.0016 18.2 4.4 1.5 1 0 0 1 1 1 1 CCCH-type zinc finger zf_CCCH_4 PF18345.1 AIN95460.1 - 0.0012 18.8 6.0 0.0023 17.9 6.0 1.5 1 0 0 1 1 1 1 Zinc finger domain Torus PF16131.5 AIN95460.1 - 0.003 18.3 1.5 0.0059 17.3 1.5 1.4 1 0 0 1 1 1 1 Torus domain zf-CCCH_2 PF14608.6 AIN95460.1 - 0.37 11.3 2.6 0.66 10.5 2.6 1.4 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger MMR_HSR1 PF01926.23 AIN95461.1 - 3.5e-16 59.3 0.1 4.7e-14 52.5 0.0 2.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 AIN95461.1 - 1.6e-06 27.7 0.0 7.6e-06 25.5 0.0 2.1 3 0 0 3 3 3 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 AIN95461.1 - 1.5e-05 25.0 0.0 0.097 12.6 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase AIG1 PF04548.16 AIN95461.1 - 0.00016 21.0 0.1 0.00037 19.9 0.1 1.6 1 0 0 1 1 1 1 AIG1 family GTP_EFTU PF00009.27 AIN95461.1 - 0.11 12.0 0.1 10 5.6 0.0 2.9 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain Dynamin_N PF00350.23 AIN95461.1 - 0.98 9.5 3.1 0.97 9.5 0.1 2.4 2 1 0 2 2 2 0 Dynamin family DSPc PF00782.20 AIN95463.1 - 3.1e-32 111.2 0.0 5.3e-32 110.4 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 AIN95463.1 - 0.00026 20.6 0.1 0.00072 19.2 0.0 1.8 2 1 0 2 2 2 1 Protein-tyrosine phosphatase Y_phosphatase2 PF03162.13 AIN95463.1 - 0.046 13.3 0.0 0.081 12.5 0.0 1.3 1 0 0 1 1 1 0 Tyrosine phosphatase family Init_tRNA_PT PF04179.12 AIN95463.1 - 0.059 13.7 0.0 0.14 12.4 0.0 1.6 1 0 0 1 1 1 0 Rit1 DUSP-like domain Fe_hyd_lg_C PF02906.14 AIN95464.1 - 1.5e-52 178.7 0.1 6.5e-52 176.6 0.0 1.9 2 0 0 2 2 2 1 Iron only hydrogenase large subunit, C-terminal domain DUF742 PF05331.11 AIN95464.1 - 0.0088 15.8 2.9 0.14 12.0 0.4 3.2 1 1 1 3 3 3 1 Protein of unknown function (DUF742) Cortexin PF11057.8 AIN95465.1 - 0.12 12.3 0.0 0.18 11.7 0.0 1.3 1 0 0 1 1 1 0 Cortexin of kidney Ank_3 PF13606.6 AIN95466.1 - 5.7e-05 23.2 0.1 0.00027 21.1 0.0 2.1 2 0 0 2 2 2 1 Ankyrin repeat Ank_5 PF13857.6 AIN95466.1 - 0.00014 22.1 0.0 0.00035 20.8 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_4 PF13637.6 AIN95466.1 - 0.00041 20.8 0.1 0.0016 19.0 0.1 2.1 1 1 0 1 1 1 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 AIN95466.1 - 0.00047 20.7 0.0 0.0017 18.9 0.0 1.9 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank PF00023.30 AIN95466.1 - 0.012 16.0 0.1 0.037 14.5 0.1 1.8 1 0 0 1 1 1 0 Ankyrin repeat SUIM_assoc PF16619.5 AIN95466.1 - 1.4 9.0 5.3 3.7 7.7 5.3 1.7 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 K_channel_TID PF07941.11 AIN95467.1 - 0.14 12.7 2.6 0.28 11.7 2.6 1.6 1 0 0 1 1 1 0 Potassium channel Kv1.4 tandem inactivation domain PTPLA PF04387.14 AIN95468.1 - 1.1e-56 191.2 5.3 1.3e-56 190.8 5.3 1.1 1 0 0 1 1 1 1 Protein tyrosine phosphatase-like protein, PTPLA P16-Arc PF04699.14 AIN95469.1 - 7.3e-05 23.3 0.0 0.00011 22.8 0.0 1.2 1 0 0 1 1 1 1 ARP2/3 complex 16 kDa subunit (p16-Arc) Mito_carr PF00153.27 AIN95470.1 - 2e-40 136.6 7.1 7.9e-14 51.4 0.0 4.0 4 0 0 4 4 4 3 Mitochondrial carrier protein Glutaredoxin PF00462.24 AIN95472.1 - 9.8e-14 51.3 0.0 1.4e-13 50.8 0.0 1.2 1 0 0 1 1 1 1 Glutaredoxin MCM PF00493.23 AIN95473.1 - 3.5e-70 235.6 0.0 5.1e-70 235.1 0.0 1.2 1 0 0 1 1 1 1 MCM P-loop domain MCM_lid PF17855.1 AIN95473.1 - 2.8e-15 56.5 0.2 2.1e-09 37.7 0.3 2.5 2 0 0 2 2 2 2 MCM AAA-lid domain MCM_OB PF17207.3 AIN95473.1 - 7.8e-10 38.7 0.5 1.1e-08 35.0 0.1 2.5 2 0 0 2 2 2 1 MCM OB domain AAA_5 PF07728.14 AIN95473.1 - 4.3e-09 36.5 0.0 8.2e-09 35.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 AIN95473.1 - 0.00015 21.2 0.2 0.096 12.1 0.0 2.6 1 1 1 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 AIN95473.1 - 0.00029 20.7 0.0 0.0007 19.5 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 AIN95473.1 - 0.011 15.4 0.1 0.044 13.5 0.1 1.9 1 1 0 1 1 1 0 Sigma-54 interaction domain AAA PF00004.29 AIN95473.1 - 0.029 14.8 0.0 0.068 13.6 0.0 1.7 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 AIN95473.1 - 0.052 13.9 0.3 0.17 12.3 0.1 2.0 2 0 0 2 2 2 0 AAA ATPase domain AAA_2 PF07724.14 AIN95473.1 - 0.21 11.7 0.0 0.45 10.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) Ribosomal_S11 PF00411.19 AIN95474.1 - 0.00032 21.1 1.3 0.00056 20.3 0.0 2.0 2 0 0 2 2 2 1 Ribosomal protein S11 Pyr_redox_2 PF07992.14 AIN95475.1 - 1.6e-62 211.5 0.1 2.3e-62 210.9 0.1 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 AIN95475.1 - 6.2e-26 90.8 0.2 1.1e-25 90.0 0.2 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 AIN95475.1 - 1.2e-19 70.7 0.0 4.9e-16 59.1 0.0 2.6 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 AIN95475.1 - 1.2e-12 47.7 0.1 3.4e-10 39.7 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 AIN95475.1 - 2.8e-05 23.0 0.9 0.19 10.4 0.0 2.6 3 0 0 3 3 3 2 HI0933-like protein FAD_binding_2 PF00890.24 AIN95475.1 - 0.00022 20.5 1.9 0.0067 15.6 1.0 2.7 3 0 0 3 3 3 1 FAD binding domain Thi4 PF01946.17 AIN95475.1 - 0.017 14.4 0.2 0.037 13.3 0.2 1.5 1 0 0 1 1 1 0 Thi4 family Glu_dehyd_C PF16912.5 AIN95475.1 - 0.092 12.2 0.0 9.9 5.6 0.0 2.5 2 0 0 2 2 2 0 Glucose dehydrogenase C-terminus NAD_binding_9 PF13454.6 AIN95475.1 - 0.11 12.5 0.0 0.28 11.2 0.0 1.7 2 0 0 2 2 2 0 FAD-NAD(P)-binding GIDA PF01134.22 AIN95475.1 - 0.19 10.8 3.4 0.13 11.3 1.6 1.8 2 1 0 2 2 2 0 Glucose inhibited division protein A DEAD PF00270.29 AIN95476.1 - 6.4e-42 143.3 0.0 1.2e-41 142.4 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 AIN95476.1 - 1.8e-23 83.0 0.0 4.5e-23 81.7 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 AIN95476.1 - 2.1e-05 24.6 0.0 4.3e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 AIN95476.1 - 0.0038 17.5 0.4 0.012 15.8 0.1 2.1 2 1 0 2 2 2 1 AAA domain DUF1143 PF06608.11 AIN95477.1 - 0.11 12.5 0.0 0.42 10.6 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1143) Pkinase PF00069.25 AIN95480.1 - 5.2e-69 232.6 0.0 6.5e-69 232.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 AIN95480.1 - 2.9e-50 171.0 0.0 4.3e-50 170.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase MORN PF02493.20 AIN95480.1 - 1.3e-39 131.8 45.3 1.6e-09 37.1 2.9 8.9 8 0 0 8 8 8 8 MORN repeat Pkinase_fungal PF17667.1 AIN95480.1 - 0.00012 21.0 0.0 0.00019 20.4 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 AIN95480.1 - 0.0029 16.6 0.0 0.0046 15.9 0.0 1.3 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 AIN95480.1 - 0.0057 16.0 0.0 0.05 12.9 0.0 2.1 2 0 0 2 2 2 1 Kinase-like RIO1 PF01163.22 AIN95480.1 - 0.1 12.2 0.0 0.43 10.2 0.0 1.7 1 1 0 2 2 2 0 RIO1 family SMC_N PF02463.19 AIN95481.1 - 1.2e-58 198.1 0.0 2.6e-58 197.0 0.0 1.8 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 AIN95481.1 - 3.5e-12 46.8 1.4 8.8e-05 22.4 0.2 2.9 2 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 AIN95481.1 - 1.5e-09 38.7 18.3 1.5e-09 38.7 18.3 6.3 2 2 2 4 4 4 1 AAA domain SMC_hinge PF06470.13 AIN95481.1 - 1.1e-07 32.2 0.2 1.4e-06 28.6 0.1 2.6 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_15 PF13175.6 AIN95481.1 - 1.4e-06 28.3 20.5 0.0033 17.2 15.2 3.5 2 1 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.6 AIN95481.1 - 9e-05 22.1 0.0 0.00024 20.8 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain DUF3800 PF12686.7 AIN95481.1 - 0.0013 19.3 0.0 0.62 10.7 0.0 4.0 2 2 0 2 2 2 1 Protein of unknown function (DUF3800) ABC_tran PF00005.27 AIN95481.1 - 0.043 14.3 20.0 0.26 11.8 3.4 5.7 3 2 0 3 3 3 0 ABC transporter TPR_2 PF07719.17 AIN95482.1 - 5.3e-25 85.5 19.5 0.00051 19.9 0.1 10.0 10 0 0 10 10 10 6 Tetratricopeptide repeat TPR_1 PF00515.28 AIN95482.1 - 3.6e-19 67.7 3.4 0.053 13.4 0.1 8.7 9 0 0 9 9 9 5 Tetratricopeptide repeat TPR_14 PF13428.6 AIN95482.1 - 2.3e-16 59.1 39.5 0.00018 22.1 0.3 10.9 7 1 5 12 12 10 6 Tetratricopeptide repeat TPR_12 PF13424.6 AIN95482.1 - 1.1e-12 48.0 31.6 0.00049 20.3 0.3 9.2 5 2 4 9 9 9 4 Tetratricopeptide repeat TPR_16 PF13432.6 AIN95482.1 - 5.1e-12 46.2 45.3 4.7e-05 24.0 2.0 8.8 9 0 0 9 9 9 4 Tetratricopeptide repeat TPR_17 PF13431.6 AIN95482.1 - 5.4e-11 42.1 2.6 0.00047 20.4 0.0 7.6 8 1 0 8 8 7 1 Tetratricopeptide repeat TPR_19 PF14559.6 AIN95482.1 - 9e-11 42.1 29.9 3.8e-05 24.1 0.3 8.6 7 2 1 9 9 9 2 Tetratricopeptide repeat ANAPC3 PF12895.7 AIN95482.1 - 8.6e-10 38.7 23.5 0.009 16.2 0.3 6.2 5 1 1 6 6 6 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.6 AIN95482.1 - 4.7e-09 35.7 0.9 0.17 12.2 0.2 6.3 7 0 0 7 7 6 2 Tetratricopeptide repeat TPR_9 PF13371.6 AIN95482.1 - 7e-09 35.7 14.3 2.9e-05 24.1 0.8 6.0 3 1 2 5 5 5 2 Tetratricopeptide repeat TPR_11 PF13414.6 AIN95482.1 - 1.2e-07 31.3 1.2 1.1 9.1 0.0 6.2 4 1 2 6 6 6 2 TPR repeat TPR_7 PF13176.6 AIN95482.1 - 2.3e-05 24.1 2.7 3.9 7.7 0.1 6.4 6 1 0 6 6 6 1 Tetratricopeptide repeat BTAD PF03704.17 AIN95482.1 - 0.00012 22.6 1.1 0.00012 22.6 1.1 4.5 3 1 1 4 4 4 1 Bacterial transcriptional activator domain TPR_6 PF13174.6 AIN95482.1 - 0.00026 21.4 16.0 0.82 10.4 0.0 8.4 9 0 0 9 9 9 1 Tetratricopeptide repeat NARP1 PF12569.8 AIN95482.1 - 0.0011 18.0 0.7 1.1 8.1 0.0 2.4 1 1 1 2 2 2 2 NMDA receptor-regulated protein 1 TPR_15 PF13429.6 AIN95482.1 - 0.0023 17.2 14.5 0.02 14.1 0.2 4.1 3 2 1 4 4 4 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 AIN95482.1 - 0.021 14.9 1.6 1.1 9.4 0.2 3.5 3 1 1 4 4 3 0 Fis1 C-terminal tetratricopeptide repeat Paf67 PF10255.9 AIN95482.1 - 0.12 11.3 0.2 0.24 10.4 0.2 1.4 1 0 0 1 1 1 0 RNA polymerase I-associated factor PAF67 Tctex-1 PF03645.13 AIN95483.1 - 3.3e-24 85.1 0.9 3.6e-24 84.9 0.9 1.0 1 0 0 1 1 1 1 Tctex-1 family Metallophos PF00149.28 AIN95484.1 - 0.0034 17.9 0.2 0.08 13.4 0.0 2.6 2 1 0 2 2 2 1 Calcineurin-like phosphoesterase NGP1NT PF08153.12 AIN95487.1 - 1.7e-43 147.9 0.4 4.6e-43 146.5 0.4 1.8 1 0 0 1 1 1 1 NGP1NT (NUC091) domain MMR_HSR1 PF01926.23 AIN95487.1 - 6.1e-18 65.0 2.1 5.3e-15 55.5 0.1 3.0 3 0 0 3 3 3 2 50S ribosome-binding GTPase FeoB_N PF02421.18 AIN95487.1 - 8.4e-06 25.4 0.1 8.4e-05 22.1 0.1 2.2 2 0 0 2 2 2 1 Ferrous iron transport protein B GTP_EFTU PF00009.27 AIN95487.1 - 0.00033 20.2 0.0 0.1 12.1 0.0 3.5 3 0 0 3 3 3 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 AIN95487.1 - 0.0021 18.0 0.0 0.032 14.1 0.0 2.5 1 1 0 1 1 1 1 RsgA GTPase Dynamin_N PF00350.23 AIN95487.1 - 0.0096 16.0 8.5 20 5.2 0.0 4.6 2 1 0 2 2 2 2 Dynamin family AAA_16 PF13191.6 AIN95487.1 - 0.027 14.8 0.1 0.1 13.0 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain CCDC53 PF10152.9 AIN95488.1 - 0.097 13.1 0.2 0.18 12.2 0.2 1.6 1 1 0 1 1 1 0 Subunit CCDC53 of WASH complex MFS_1 PF07690.16 AIN95489.1 - 1.7e-30 106.2 34.3 6.6e-21 74.6 10.2 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily ATP-synt_ab PF00006.25 AIN95491.1 - 1e-66 224.7 0.1 1.6e-66 224.0 0.1 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.27 AIN95491.1 - 7.3e-09 36.0 0.6 4.9e-08 33.3 0.0 2.2 2 0 0 2 2 2 1 ATP synthase alpha/beta chain, C terminal domain His_kinase PF06580.13 AIN95491.1 - 1.1 9.6 4.5 1.1 9.6 0.4 2.4 1 1 1 2 2 2 0 Histidine kinase ADH_zinc_N PF00107.26 AIN95492.1 - 7.7e-07 29.2 0.5 1.6e-06 28.1 0.1 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase tRNA_m1G_MT PF01746.21 AIN95492.1 - 0.12 12.0 0.0 0.2 11.4 0.0 1.2 1 0 0 1 1 1 0 tRNA (Guanine-1)-methyltransferase LSM PF01423.22 AIN95494.1 - 0.00044 19.9 0.2 0.0026 17.4 0.2 2.0 1 1 0 1 1 1 1 LSM domain Pkinase PF00069.25 AIN95495.1 - 3.6e-67 226.5 0.0 4.1e-67 226.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 AIN95495.1 - 2.3e-31 109.0 0.0 3e-31 108.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 AIN95495.1 - 0.00081 18.8 0.0 0.0014 18.0 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 AIN95495.1 - 0.0038 17.2 0.0 0.06 13.3 0.0 2.2 1 1 1 2 2 2 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 AIN95495.1 - 0.019 14.0 0.0 0.025 13.5 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain Pkinase_fungal PF17667.1 AIN95495.1 - 0.081 11.7 0.0 0.21 10.3 0.0 1.6 1 1 1 2 2 2 0 Fungal protein kinase Choline_kinase PF01633.20 AIN95495.1 - 0.14 11.8 0.0 0.2 11.2 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase Motile_Sperm PF00635.26 AIN95496.1 - 0.00084 19.2 0.0 0.0054 16.6 0.0 2.1 2 0 0 2 2 2 1 MSP (Major sperm protein) domain NDUF_B5 PF09781.9 AIN95497.1 - 0.046 13.3 0.6 0.081 12.5 0.6 1.4 1 0 0 1 1 1 0 NADH:ubiquinone oxidoreductase, NDUFB5/SGDH subunit RDD PF06271.12 AIN95498.1 - 0.15 12.2 0.1 0.15 12.2 0.1 2.7 3 0 0 3 3 3 0 RDD family FKBP_N PF01346.18 AIN95498.1 - 0.17 12.9 0.9 0.3 12.1 0.1 1.8 2 0 0 2 2 2 0 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase DEAD PF00270.29 AIN95499.1 - 3e-32 111.8 0.1 1.5e-16 60.6 0.0 2.5 2 0 0 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.31 AIN95499.1 - 3e-20 72.6 0.0 9.6e-20 71.0 0.1 1.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 AIN95499.1 - 0.00021 21.3 0.0 0.00064 19.8 0.0 1.7 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit FCP1_C PF09309.10 AIN95499.1 - 0.16 11.8 4.3 0.34 10.7 4.3 1.5 1 0 0 1 1 1 0 FCP1, C-terminal COG4 PF08318.12 AIN95500.1 - 1.2e-45 156.1 0.0 3.1e-45 154.7 0.0 1.7 2 0 0 2 2 2 1 COG4 transport protein RINT1_TIP1 PF04437.13 AIN95500.1 - 3e-05 23.1 0.7 5e-05 22.4 0.1 1.7 2 0 0 2 2 2 1 RINT-1 / TIP-1 family Surp PF01805.20 AIN95501.1 - 4.2e-09 36.2 0.0 8e-09 35.4 0.0 1.4 1 0 0 1 1 1 1 Surp module ubiquitin PF00240.23 AIN95502.1 - 0.00065 19.4 0.0 0.0013 18.4 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family CAF20 PF17052.5 AIN95502.1 - 1.3 9.1 6.7 2.7 8.1 6.7 1.4 1 0 0 1 1 1 0 Cap associated factor NST1 PF13945.6 AIN95502.1 - 1.6 8.8 6.9 3 7.9 6.9 1.4 1 0 0 1 1 1 0 Salt tolerance down-regulator Kinesin PF00225.23 AIN95503.1 - 4.8e-88 295.3 0.1 9.2e-88 294.4 0.1 1.4 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 AIN95503.1 - 7.5e-21 74.6 0.5 1.7e-17 63.7 0.0 3.2 3 0 0 3 3 3 2 Microtubule binding Ank_2 PF12796.7 AIN95504.1 - 1.9e-44 150.2 15.6 1.7e-11 44.5 0.1 11.7 10 3 3 13 13 13 8 Ankyrin repeats (3 copies) Ank_4 PF13637.6 AIN95504.1 - 7.8e-36 122.0 18.7 1.3e-05 25.6 0.0 13.4 13 2 2 15 15 15 9 Ankyrin repeats (many copies) Ank_3 PF13606.6 AIN95504.1 - 1.6e-31 104.8 26.1 0.0007 19.9 0.0 16.4 17 1 0 17 17 17 7 Ankyrin repeat Ank_5 PF13857.6 AIN95504.1 - 5.9e-28 96.6 15.9 0.00013 22.2 0.0 12.3 11 1 1 12 12 12 6 Ankyrin repeats (many copies) Ank PF00023.30 AIN95504.1 - 7e-22 76.9 29.7 5e-05 23.6 0.1 16.2 16 0 0 16 16 16 5 Ankyrin repeat Rhamno_transf PF11316.8 AIN95504.1 - 0.17 11.2 0.1 0.4 10.0 0.1 1.5 1 0 0 1 1 1 0 Putative rhamnosyl transferase Luteo_PO PF04662.13 AIN95504.1 - 0.18 11.5 0.1 9.8 5.8 0.0 2.4 2 0 0 2 2 2 0 Luteovirus P0 protein LRR_6 PF13516.6 AIN95505.1 - 0.00011 21.9 6.8 0.72 10.1 0.1 4.5 4 0 0 4 4 4 3 Leucine Rich repeat LRR_4 PF12799.7 AIN95505.1 - 5 7.7 4.6 0.97 9.9 0.4 2.0 2 0 0 2 2 2 0 Leucine Rich repeats (2 copies) Nitroreductase PF00881.24 AIN95506.1 - 4.5e-31 108.2 0.0 5.9e-31 107.8 0.0 1.2 1 0 0 1 1 1 1 Nitroreductase family TM1586_NiRdase PF14512.6 AIN95506.1 - 0.013 15.1 0.0 1.5 8.4 0.0 2.3 2 0 0 2 2 2 0 Putative TM nitroreductase Mtc PF03820.17 AIN95508.1 - 2.6e-90 302.7 1.7 3.1e-90 302.4 1.7 1.0 1 0 0 1 1 1 1 Tricarboxylate carrier SHIPPO-rpt PF07004.12 AIN95509.1 - 2.7e-72 236.6 182.7 0.0021 18.9 0.0 40.6 41 1 0 41 41 41 38 Sperm-tail PG-rich repeat Cyclin PF08613.11 AIN95511.1 - 3.2e-20 73.1 0.2 4.7e-19 69.3 0.0 3.2 2 0 0 2 2 2 1 Cyclin Cyclin_N PF00134.23 AIN95511.1 - 0.0025 17.6 0.0 0.0057 16.4 0.0 1.6 1 0 0 1 1 1 1 Cyclin, N-terminal domain PTCRA PF15028.6 AIN95511.1 - 0.0086 15.8 1.6 3.1 7.5 0.3 3.4 2 0 0 2 2 2 2 Pre-T-cell antigen receptor DSPc PF00782.20 AIN95512.1 - 1.9e-18 66.5 0.1 1.1e-06 28.5 0.0 3.4 3 0 0 3 3 3 3 Dual specificity phosphatase, catalytic domain BSP_II PF05432.11 AIN95512.1 - 0.0084 15.8 6.8 0.029 14.1 6.8 1.9 1 0 0 1 1 1 1 Bone sialoprotein II (BSP-II) Radial_spoke PF04712.12 AIN95512.1 - 0.023 13.6 3.2 0.039 12.9 3.2 1.3 1 0 0 1 1 1 0 Radial spokehead-like protein PPP4R2 PF09184.11 AIN95512.1 - 0.027 14.1 5.4 0.062 12.9 5.4 1.5 1 0 0 1 1 1 0 PPP4R2 Myc_N PF01056.18 AIN95512.1 - 0.036 14.0 5.5 0.032 14.1 3.0 2.3 2 0 0 2 2 2 0 Myc amino-terminal region CENP-B_dimeris PF09026.10 AIN95512.1 - 0.56 10.6 7.8 1.8 9.0 7.8 1.8 1 0 0 1 1 1 0 Centromere protein B dimerisation domain DNA_pol_phi PF04931.13 AIN95512.1 - 0.79 7.7 5.4 1.2 7.2 5.4 1.1 1 0 0 1 1 1 0 DNA polymerase phi DUF4746 PF15928.5 AIN95512.1 - 1.8 7.9 6.9 3.4 7.0 6.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) FAM176 PF14851.6 AIN95512.1 - 2.2 7.9 6.3 0.6 9.8 2.5 2.0 2 0 0 2 2 2 0 FAM176 family Vta1 PF04652.16 AIN95514.1 - 5.1e-34 117.3 1.1 8.7e-34 116.6 1.1 1.4 1 0 0 1 1 1 1 Vta1 like Vta1_C PF18097.1 AIN95514.1 - 2.1e-14 52.9 2.6 2.1e-14 52.9 2.6 2.0 2 0 0 2 2 2 1 Vta1 C-terminal domain TFIIA PF03153.13 AIN95514.1 - 5.1 7.0 13.6 6.6 6.6 13.6 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Wyosine_form PF08608.12 AIN95515.1 - 3.4e-20 72.1 0.8 1.1e-14 54.5 0.0 2.7 2 0 0 2 2 2 2 Wyosine base formation Radical_SAM PF04055.21 AIN95515.1 - 7.5e-20 72.0 0.0 1.5e-19 71.0 0.0 1.5 1 0 0 1 1 1 1 Radical SAM superfamily Flavodoxin_1 PF00258.25 AIN95515.1 - 1.1e-12 48.3 0.0 1e-11 45.2 0.0 2.3 2 0 0 2 2 2 1 Flavodoxin Kinesin PF00225.23 AIN95516.1 - 8.3e-80 268.2 0.0 1e-52 179.1 0.0 2.3 2 0 0 2 2 2 2 Kinesin motor domain Microtub_bd PF16796.5 AIN95516.1 - 3.7e-11 43.2 0.0 1.8e-09 37.7 0.0 2.4 2 0 0 2 2 2 1 Microtubule binding Cortex-I_coil PF09304.10 AIN95516.1 - 0.011 15.9 0.0 0.028 14.6 0.0 1.6 1 0 0 1 1 1 0 Cortexillin I, coiled coil AAA_16 PF13191.6 AIN95516.1 - 0.19 12.1 2.7 0.24 11.8 0.0 2.6 3 0 0 3 3 3 0 AAA ATPase domain MAM33 PF02330.16 AIN95519.1 - 9.8e-15 55.1 0.0 1.6e-14 54.4 0.0 1.5 1 1 0 1 1 1 1 Mitochondrial glycoprotein zf-MYND PF01753.18 AIN95520.1 - 3.3e-11 43.1 13.5 6.8e-11 42.1 13.5 1.6 1 0 0 1 1 1 1 MYND finger RNA_pol_Rpc4 PF05132.14 AIN95520.1 - 0.086 13.3 0.0 0.65 10.4 0.0 2.0 2 0 0 2 2 2 0 RNA polymerase III RPC4 Spc7_N PF15402.6 AIN95520.1 - 0.34 9.1 4.7 0.58 8.4 4.7 1.3 1 0 0 1 1 1 0 N-terminus of kinetochore NMS complex subunit Spc7 Got1 PF04178.12 AIN95521.1 - 1.8e-31 108.8 15.6 2.4e-31 108.5 15.6 1.1 1 0 0 1 1 1 1 Got1/Sft2-like family Bac_export_2 PF01312.19 AIN95521.1 - 0.0058 15.9 0.8 0.0062 15.8 0.8 1.1 1 0 0 1 1 1 1 FlhB HrpN YscU SpaS Family DUF4064 PF13273.6 AIN95521.1 - 0.43 10.9 11.8 1.3 9.3 11.2 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF4064) Claudin_2 PF13903.6 AIN95521.1 - 0.74 9.5 9.0 0.75 9.5 7.7 1.7 1 1 1 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction ATP-synt_I PF03899.15 AIN95521.1 - 0.83 10.1 13.7 3.4 8.1 7.9 2.2 1 1 1 2 2 2 0 ATP synthase I chain PNP_UDP_1 PF01048.20 AIN95523.1 - 1.5e-39 135.7 0.5 1.9e-39 135.3 0.5 1.1 1 0 0 1 1 1 1 Phosphorylase superfamily zf-C2HC_2 PF13913.6 AIN95525.1 - 5e-13 48.6 10.1 1.7e-07 31.0 1.5 2.4 2 0 0 2 2 2 2 zinc-finger of a C2HC-type zf-CpG_bind_C PF12269.8 AIN95525.1 - 0.0062 16.3 0.6 0.99 9.1 0.1 2.4 2 0 0 2 2 2 2 CpG binding protein zinc finger C terminal domain zf-C2H2_4 PF13894.6 AIN95525.1 - 0.0094 16.7 1.0 5.1 8.2 0.1 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.26 AIN95525.1 - 0.067 13.7 0.8 15 6.3 0.1 2.6 2 0 0 2 2 2 0 Zinc finger, C2H2 type zinc_ribbon_9 PF14369.6 AIN95525.1 - 3.6 7.9 5.2 0.5 10.7 0.2 2.1 2 0 0 2 2 2 0 zinc-ribbon SUIM_assoc PF16619.5 AIN95527.1 - 2 8.6 11.6 0.46 10.6 4.7 3.7 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 MMS1_N PF10433.9 AIN95529.1 - 9.2e-36 123.5 0.0 3e-20 72.3 0.0 4.2 3 1 0 3 3 3 3 Mono-functional DNA-alkylating methyl methanesulfonate N-term CPSF_A PF03178.15 AIN95529.1 - 1.6e-15 57.2 0.0 1.2e-11 44.5 0.0 3.0 3 0 0 3 3 3 2 CPSF A subunit region ELH PF02323.15 AIN95529.1 - 0.1 11.9 0.4 0.27 10.6 0.4 1.6 1 0 0 1 1 1 0 Egg-laying hormone precursor LRR_8 PF13855.6 AIN95530.1 - 1.7e-07 30.9 5.1 0.00025 20.7 1.0 2.1 1 1 2 3 3 3 3 Leucine rich repeat LRR_4 PF12799.7 AIN95530.1 - 0.017 15.5 1.1 0.1 13.0 0.4 2.4 1 1 0 2 2 2 0 Leucine Rich repeats (2 copies) Flagellar_rod PF05149.12 AIN95531.1 - 6.4e-87 291.7 21.7 6.4e-87 291.7 21.7 2.2 3 0 0 3 3 3 1 Paraflagellar rod protein UQ_con PF00179.26 AIN95532.1 - 5.6e-10 39.0 0.0 1.2e-09 37.9 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Peptidase_C98 PF15499.6 AIN95532.1 - 0.081 12.4 0.0 0.13 11.7 0.0 1.3 1 0 0 1 1 1 0 Ubiquitin-specific peptidase-like, SUMO isopeptidase NUP50 PF08911.11 AIN95533.1 - 0.017 15.7 0.2 0.17 12.5 0.2 2.9 1 0 0 1 1 1 0 NUP50 (Nucleoporin 50 kDa) DUF2520 PF10728.9 AIN95533.1 - 1.9 8.3 5.6 0.48 10.2 1.3 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF2520) Peptidase_M28 PF04389.17 AIN95534.1 - 3.1e-16 59.7 1.1 1.2e-05 25.1 0.0 3.4 3 0 0 3 3 3 3 Peptidase family M28 Peptidase_M49 PF03571.15 AIN95535.1 - 4.7e-217 721.7 0.0 5.9e-217 721.4 0.0 1.0 1 0 0 1 1 1 1 Peptidase family M49 Cache_3-Cache_2 PF17201.4 AIN95535.1 - 0.029 13.7 0.3 0.06 12.6 0.0 1.5 2 0 0 2 2 2 0 Cache 3/Cache 2 fusion domain COG4 PF08318.12 AIN95535.1 - 0.13 11.3 0.1 1.4 7.9 0.0 2.0 2 0 0 2 2 2 0 COG4 transport protein Rhodanese PF00581.20 AIN95536.1 - 7e-13 49.0 0.0 3.8e-07 30.6 0.0 2.2 2 0 0 2 2 2 2 Rhodanese-like domain DUF1930 PF09122.10 AIN95538.1 - 6.1e-35 119.0 0.1 1.1e-34 118.2 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1930) Rhodanese PF00581.20 AIN95538.1 - 5.7e-14 52.5 0.0 4.1e-07 30.5 0.0 2.3 2 0 0 2 2 2 2 Rhodanese-like domain Complex1_51K PF01512.17 AIN95539.1 - 1.4e-44 151.7 0.0 2.7e-44 150.7 0.0 1.4 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase 51 Kd subunit NADH_4Fe-4S PF10589.9 AIN95539.1 - 5.2e-29 100.1 0.0 1.2e-28 99.0 0.0 1.6 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region SLBB PF10531.9 AIN95539.1 - 2.9e-07 30.2 0.0 5.2e-07 29.4 0.0 1.4 1 0 0 1 1 1 1 SLBB domain Ribosomal_S26e PF01283.19 AIN95539.1 - 0.12 12.8 0.1 0.62 10.5 0.0 1.9 2 0 0 2 2 2 0 Ribosomal protein S26e NDUF_B7 PF05676.13 AIN95540.1 - 0.032 13.9 0.5 0.044 13.5 0.5 1.3 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) zf-C2HC5 PF06221.13 AIN95541.1 - 0.0012 18.8 5.6 0.0012 18.8 5.6 1.9 2 1 0 2 2 2 1 Putative zinc finger motif, C2HC5-type zf-C3HC4_3 PF13920.6 AIN95541.1 - 0.0013 18.6 7.4 0.0023 17.7 7.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 AIN95541.1 - 0.035 14.1 7.1 0.06 13.3 7.1 1.4 1 0 0 1 1 1 0 zinc-RING finger domain UPF0506 PF11703.8 AIN95541.1 - 1.3 9.4 8.7 0.45 10.9 5.0 2.1 2 1 0 2 2 2 0 UPF0506 zf-RING_2 PF13639.6 AIN95541.1 - 1.5 9.3 8.8 3 8.3 8.8 1.6 1 0 0 1 1 1 0 Ring finger domain UPF0020 PF01170.18 AIN95542.1 - 3.5e-12 46.4 0.0 3.2e-11 43.3 0.0 2.2 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 N6_Mtase PF02384.16 AIN95542.1 - 0.0019 17.5 0.0 0.014 14.7 0.0 2.1 2 0 0 2 2 2 1 N-6 DNA Methylase N6_N4_Mtase PF01555.18 AIN95542.1 - 0.0067 16.2 0.0 0.084 12.6 0.0 2.3 2 0 0 2 2 2 1 DNA methylase SR-25 PF10500.9 AIN95542.1 - 0.039 13.6 8.0 0.067 12.8 8.0 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Band_7 PF01145.25 AIN95545.1 - 3.8e-25 88.9 0.0 7.5e-25 88.0 0.0 1.4 1 0 0 1 1 1 1 SPFH domain / Band 7 family Band_7_C PF16200.5 AIN95545.1 - 2.9e-23 81.7 3.1 2.5e-22 78.7 0.7 2.4 2 0 0 2 2 2 1 C-terminal region of band_7 Band_7_1 PF13421.6 AIN95545.1 - 0.013 15.2 0.1 0.026 14.2 0.1 1.5 1 0 0 1 1 1 0 SPFH domain-Band 7 family FBPase PF00316.20 AIN95546.1 - 0.069 12.6 0.0 0.13 11.7 0.0 1.4 1 0 0 1 1 1 0 Fructose-1-6-bisphosphatase, N-terminal domain AFG1_ATPase PF03969.16 AIN95547.1 - 8.8e-83 278.2 0.9 1.3e-75 254.6 0.1 3.2 3 1 0 3 3 3 3 AFG1-like ATPase AAA_22 PF13401.6 AIN95547.1 - 0.0031 17.8 0.0 0.006 16.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain Bac_DnaA PF00308.18 AIN95547.1 - 0.077 12.8 0.9 0.46 10.3 0.0 2.4 2 1 0 3 3 3 0 Bacterial dnaA protein ABC_tran PF00005.27 AIN95547.1 - 0.17 12.4 0.0 0.36 11.4 0.0 1.5 1 0 0 1 1 1 0 ABC transporter Lectin_leg-like PF03388.13 AIN95548.1 - 1.6e-11 44.0 0.0 4.5e-07 29.4 0.0 3.0 2 1 1 3 3 3 2 Legume-like lectin family DMAP1 PF05499.12 AIN95548.1 - 0.021 14.7 0.3 0.043 13.7 0.3 1.4 1 0 0 1 1 1 0 DNA methyltransferase 1-associated protein 1 (DMAP1) MORN PF02493.20 AIN95549.1 - 7.2e-23 79.1 37.0 9e-08 31.6 1.8 7.0 6 0 0 6 6 6 5 MORN repeat GCD14 PF08704.10 AIN95549.1 - 0.17 11.6 0.2 0.4 10.3 0.2 1.5 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit Rad21_Rec8_N PF04825.13 AIN95550.1 - 2.5e-28 98.5 0.1 4.8e-28 97.5 0.1 1.5 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.16 AIN95550.1 - 1.8e-07 30.3 0.2 2.3e-06 26.8 0.0 2.4 2 0 0 2 2 2 1 Conserved region of Rad21 / Rec8 like protein CNDH2_C PF16858.5 AIN95550.1 - 0.12 12.3 0.0 0.25 11.2 0.0 1.5 1 0 0 1 1 1 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term SMC_ScpA PF02616.14 AIN95550.1 - 0.15 12.0 0.1 18 5.1 0.1 2.2 2 0 0 2 2 2 0 Segregation and condensation protein ScpA Methyltransf_31 PF13847.6 AIN95551.1 - 1.8e-09 37.5 0.0 2.3e-09 37.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 AIN95551.1 - 2e-08 34.8 0.0 7e-08 33.1 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 AIN95551.1 - 5.3e-08 33.4 0.0 2.9e-07 31.1 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 AIN95551.1 - 4.6e-06 27.3 0.0 9.6e-06 26.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain TPMT PF05724.11 AIN95551.1 - 2.6e-05 24.0 0.0 0.00061 19.5 0.0 2.2 2 0 0 2 2 2 1 Thiopurine S-methyltransferase (TPMT) NodS PF05401.11 AIN95551.1 - 3.6e-05 23.5 0.0 7.3e-05 22.5 0.0 1.4 1 1 0 1 1 1 1 Nodulation protein S (NodS) Methyltransf_8 PF05148.15 AIN95551.1 - 0.00017 21.5 0.0 0.13 12.1 0.0 2.1 2 0 0 2 2 2 2 Hypothetical methyltransferase Pox_MCEL PF03291.16 AIN95551.1 - 0.0072 15.5 0.0 0.026 13.6 0.0 1.8 1 1 0 1 1 1 1 mRNA capping enzyme MTS PF05175.14 AIN95551.1 - 0.0081 15.7 0.0 0.036 13.6 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_32 PF13679.6 AIN95551.1 - 0.0094 16.0 0.0 0.015 15.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 AIN95551.1 - 0.012 14.9 0.0 0.022 14.0 0.0 1.4 1 1 0 1 1 1 0 Mycolic acid cyclopropane synthetase EutQ PF06249.12 AIN95551.1 - 0.05 13.4 0.0 0.1 12.4 0.0 1.5 1 1 0 1 1 1 0 Ethanolamine utilisation protein EutQ RRM_1 PF00076.22 AIN95552.1 - 1.8e-08 34.0 0.0 0.041 13.7 0.0 4.3 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PRIMA1 PF16101.5 AIN95553.1 - 5.7 7.0 8.8 1.9 8.5 1.6 2.6 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 vATP-synt_AC39 PF01992.16 AIN95554.1 - 2.2e-88 297.0 0.6 2.4e-88 296.9 0.6 1.0 1 0 0 1 1 1 1 ATP synthase (C/AC39) subunit LRR_4 PF12799.7 AIN95555.1 - 3.9e-10 39.8 5.4 0.019 15.4 0.1 6.0 5 1 1 6 6 6 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 AIN95555.1 - 1.4e-07 31.2 7.3 0.67 9.8 0.0 5.9 6 0 0 6 6 6 3 Leucine rich repeat LRR_6 PF13516.6 AIN95555.1 - 2.2e-05 24.1 5.1 2 8.7 0.1 5.5 5 0 0 5 5 5 1 Leucine Rich repeat LRR_1 PF00560.33 AIN95555.1 - 8.1e-05 22.6 6.0 2.4 9.1 0.0 5.6 6 0 0 6 6 6 2 Leucine Rich Repeat ERM PF00769.19 AIN95555.1 - 0.47 10.2 10.9 0.86 9.4 10.9 1.4 1 0 0 1 1 1 0 Ezrin/radixin/moesin family DUF641 PF04859.12 AIN95555.1 - 0.74 10.2 6.1 1.6 9.1 6.1 1.5 1 0 0 1 1 1 0 Plant protein of unknown function (DUF641) CCDC92 PF14916.6 AIN95555.1 - 1.3 8.9 3.5 7.2 6.5 0.8 2.4 2 0 0 2 2 2 0 Coiled-coil domain of unknown function Spc7 PF08317.11 AIN95555.1 - 1.6 7.5 5.3 2.6 6.8 5.3 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein ELO PF01151.18 AIN95556.1 - 1.4e-41 142.7 33.4 2.8e-41 141.7 33.4 1.4 1 1 0 1 1 1 1 GNS1/SUR4 family NDUFA12 PF05071.16 AIN95557.1 - 0.012 16.5 0.2 0.047 14.5 0.2 2.0 1 0 0 1 1 1 0 NADH ubiquinone oxidoreductase subunit NDUFA12 DUF346 PF03984.13 AIN95557.1 - 0.047 13.4 5.4 0.2 11.4 2.9 2.6 2 0 0 2 2 2 0 Repeat of unknown function (DUF346) JAKMIP_CC3 PF16034.5 AIN95558.1 - 0.00079 19.4 4.1 0.00079 19.4 4.1 2.7 2 0 0 2 2 2 1 JAKMIP CC3 domain ATP-synt_F6 PF05511.11 AIN95558.1 - 0.058 13.8 0.0 0.36 11.3 0.0 2.4 1 0 0 1 1 1 0 Mitochondrial ATP synthase coupling factor 6 MetOD1 PF18546.1 AIN95558.1 - 0.12 12.3 0.7 0.45 10.5 0.0 2.1 2 0 0 2 2 2 0 Metanogen output domain 1 Cep57_CLD_2 PF14197.6 AIN95558.1 - 5.1 7.3 8.4 2.7 8.1 4.5 2.7 2 0 0 2 2 2 0 Centrosome localisation domain of PPC89 FAM76 PF16046.5 AIN95558.1 - 7.9 5.7 12.5 4.4 6.6 8.3 2.5 1 1 1 2 2 2 0 FAM76 protein Prefoldin_2 PF01920.20 AIN95559.1 - 3.6e-18 65.5 3.8 3.6e-18 65.5 3.8 2.0 1 1 1 2 2 2 1 Prefoldin subunit DHR10 PF18595.1 AIN95559.1 - 0.038 14.0 0.9 0.038 14.0 0.9 2.2 2 0 0 2 2 2 0 Designed helical repeat protein 10 domain PCRF PF03462.18 AIN95559.1 - 0.11 12.4 0.1 0.11 12.4 0.1 2.0 1 1 1 2 2 2 0 PCRF domain Ca_chan_IQ PF08763.11 AIN95559.1 - 0.39 11.0 2.5 0.74 10.1 1.2 2.0 2 0 0 2 2 2 0 Voltage gated calcium channel IQ domain kleA_kleC PF17383.2 AIN95559.1 - 0.47 10.8 3.9 0.24 11.7 1.9 1.6 2 0 0 2 2 2 0 Uncharacterized KorC regulated protein A DASH_Spc19 PF08287.11 AIN95559.1 - 0.9 9.4 14.2 0.76 9.7 6.1 2.1 1 1 0 2 2 2 0 Spc19 APG6_N PF17675.1 AIN95559.1 - 2.7 8.5 16.3 5 7.7 9.4 2.1 1 1 0 2 2 2 0 Apg6 coiled-coil region FlaC_arch PF05377.11 AIN95559.1 - 3.9 8.0 7.0 29 5.1 1.6 2.9 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) XhlA PF10779.9 AIN95559.1 - 4.4 7.6 5.6 0.61 10.3 1.1 2.0 3 0 0 3 3 3 0 Haemolysin XhlA YabA PF06156.13 AIN95559.1 - 4.6 7.9 11.1 3.3 8.4 0.6 2.1 1 1 1 2 2 2 0 Initiation control protein YabA LRR_8 PF13855.6 AIN95560.1 - 9e-26 89.4 35.9 2.1e-09 37.0 1.8 6.0 3 2 4 7 7 7 6 Leucine rich repeat LRR_4 PF12799.7 AIN95560.1 - 1.5e-25 88.8 27.6 4.9e-05 23.6 2.0 7.5 4 3 4 9 9 9 7 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 AIN95560.1 - 1.3e-20 73.6 5.6 8.2e-09 35.2 0.1 3.1 2 1 0 3 3 3 3 Leucine-rich repeat LRR_6 PF13516.6 AIN95560.1 - 1.1e-06 28.2 18.2 1.2 9.3 0.1 8.3 10 0 0 10 10 10 3 Leucine Rich repeat LRR_1 PF00560.33 AIN95560.1 - 0.006 17.0 22.0 12 6.9 0.1 9.2 9 1 1 10 10 10 1 Leucine Rich Repeat LRR_4 PF12799.7 AIN95561.1 - 0.00041 20.7 0.1 0.028 14.8 0.0 2.9 2 0 0 2 2 2 1 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 AIN95561.1 - 0.018 14.8 0.0 0.59 9.9 0.0 2.3 2 0 0 2 2 2 0 Leucine rich repeat CENP-T_C PF15511.6 AIN95562.1 - 2e-05 24.6 0.1 3.3e-05 24.0 0.0 1.3 1 1 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CBFD_NFYB_HMF PF00808.23 AIN95562.1 - 0.0023 18.2 0.4 0.0032 17.7 0.0 1.4 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TAF PF02969.17 AIN95562.1 - 0.0028 17.8 0.1 0.0045 17.1 0.1 1.3 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) Bromo_TP PF07524.13 AIN95562.1 - 0.005 16.8 0.0 0.0059 16.6 0.0 1.2 1 0 0 1 1 1 1 Bromodomain associated Histone PF00125.24 AIN95562.1 - 0.014 15.7 1.6 0.026 14.9 1.6 1.5 1 1 0 1 1 1 0 Core histone H2A/H2B/H3/H4 TFIID-31kDa PF02291.15 AIN95562.1 - 0.11 12.6 0.0 0.14 12.2 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit PCP_red PF08369.10 AIN95562.1 - 0.28 11.4 1.5 1.3 9.3 0.1 2.4 2 1 0 2 2 2 0 Proto-chlorophyllide reductase 57 kD subunit LRR_4 PF12799.7 AIN95563.1 - 6.5e-23 80.4 0.6 0.0076 16.7 0.1 8.1 6 1 3 9 9 9 8 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 AIN95563.1 - 1.9e-08 33.7 23.5 0.0095 15.9 0.0 11.0 13 0 0 13 13 13 3 Leucine Rich repeat LRR_8 PF13855.6 AIN95563.1 - 5e-08 32.6 8.6 0.13 12.1 0.0 6.4 4 1 3 7 7 7 4 Leucine rich repeat LRR_9 PF14580.6 AIN95563.1 - 0.027 14.0 5.9 0.39 10.2 0.1 3.7 2 1 1 4 4 4 0 Leucine-rich repeat WD40 PF00400.32 AIN95564.1 - 2.1e-53 177.1 29.4 3.8e-10 40.2 0.2 7.5 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 AIN95564.1 - 8e-08 32.5 0.2 0.005 17.1 0.0 4.6 1 1 4 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 AIN95564.1 - 2.8e-07 30.1 1.3 0.011 15.1 0.1 3.4 2 2 1 3 3 3 2 WD40-like domain Nup160 PF11715.8 AIN95564.1 - 2.1e-06 26.7 11.7 0.018 13.7 0.1 5.7 1 1 5 6 6 6 4 Nucleoporin Nup120/160 RhlB PF12300.8 AIN95564.1 - 0.0026 17.9 3.4 0.65 10.1 0.5 2.7 2 1 0 2 2 2 2 ATP-dependent RNA helicase RhlB MRP-L46 PF11788.8 AIN95565.1 - 3.7e-12 47.0 0.0 1.1e-11 45.5 0.0 1.8 1 1 0 1 1 1 1 39S mitochondrial ribosomal protein L46 PUF PF00806.19 AIN95566.1 - 2.5e-26 89.8 7.1 2.8e-06 26.7 0.0 6.1 6 0 0 6 6 6 5 Pumilio-family RNA binding repeat Glycolytic PF00274.19 AIN95566.1 - 0.13 11.0 0.0 0.19 10.4 0.0 1.2 1 0 0 1 1 1 0 Fructose-bisphosphate aldolase class-I DNApol_Exo PF18136.1 AIN95567.1 - 0.037 13.2 1.8 0.057 12.5 1.8 1.3 1 0 0 1 1 1 0 DNA mitochondrial polymerase exonuclease domain EF1G PF00647.19 AIN95567.1 - 0.14 12.2 0.2 0.42 10.7 0.0 1.9 2 0 0 2 2 2 0 Elongation factor 1 gamma, conserved domain bZIP_1 PF00170.21 AIN95567.1 - 0.2 11.8 0.3 0.2 11.8 0.3 3.5 3 0 0 3 3 3 0 bZIP transcription factor Uso1_p115_C PF04871.13 AIN95567.1 - 0.23 11.8 15.8 0.16 12.3 7.0 2.4 1 1 1 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region TolA_bind_tri PF16331.5 AIN95567.1 - 1.2 9.2 8.8 8.7 6.5 0.1 3.4 2 1 1 3 3 3 0 TolA binding protein trimerisation CdvA PF18822.1 AIN95567.1 - 7.9 6.3 11.1 1.3 8.9 1.5 3.2 2 1 0 3 3 3 0 CdvA-like coiled-coil domain ABC2_membrane PF01061.24 AIN95569.1 - 3.4e-38 131.2 15.8 3.4e-38 131.2 15.8 1.4 2 0 0 2 2 1 1 ABC-2 type transporter ABC_tran PF00005.27 AIN95569.1 - 7.4e-22 78.3 0.0 1.1e-21 77.7 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 AIN95569.1 - 0.00018 21.4 0.1 0.1 12.4 0.0 2.3 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 AIN95569.1 - 0.0011 18.5 0.1 0.026 14.0 0.1 2.1 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain ABC2_membrane_3 PF12698.7 AIN95569.1 - 0.0016 17.6 9.5 0.0029 16.8 9.5 1.4 1 0 0 1 1 1 1 ABC-2 family transporter protein AAA_16 PF13191.6 AIN95569.1 - 0.0053 17.2 0.1 0.011 16.1 0.1 1.5 1 1 0 1 1 1 1 AAA ATPase domain RsgA_GTPase PF03193.16 AIN95569.1 - 0.0082 16.1 0.1 0.015 15.2 0.1 1.3 1 0 0 1 1 1 1 RsgA GTPase NACHT PF05729.12 AIN95569.1 - 0.012 15.5 0.1 0.024 14.6 0.1 1.5 1 0 0 1 1 1 0 NACHT domain AAA_23 PF13476.6 AIN95569.1 - 0.027 15.0 0.0 0.042 14.3 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 AIN95569.1 - 0.049 13.4 0.4 0.1 12.4 0.4 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF87 PF01935.17 AIN95569.1 - 0.068 13.3 0.4 0.12 12.5 0.4 1.3 1 0 0 1 1 1 0 Helicase HerA, central domain AAA_22 PF13401.6 AIN95569.1 - 0.075 13.3 0.0 0.45 10.8 0.0 2.2 3 0 0 3 3 3 0 AAA domain AAA_24 PF13479.6 AIN95569.1 - 0.077 12.7 0.2 0.85 9.3 0.1 2.1 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 AIN95569.1 - 0.12 12.5 0.1 0.24 11.5 0.1 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase CytochromB561_N PF09786.9 AIN95570.1 - 9.7e-09 34.8 0.1 1.7e-08 34.0 0.1 1.3 1 0 0 1 1 1 1 Cytochrome B561, N terminal Pro_isomerase PF00160.21 AIN95571.1 - 2.3e-50 170.9 0.5 2.7e-50 170.7 0.5 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD DUF1768 PF08719.11 AIN95572.1 - 1.3e-25 90.6 0.0 1.5e-25 90.3 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1768) Proteasome PF00227.26 AIN95573.1 - 3.3e-27 95.2 0.0 4.9e-27 94.7 0.0 1.3 1 0 0 1 1 1 1 Proteasome subunit HD PF01966.22 AIN95575.1 - 1e-13 51.6 2.7 1.5e-13 51.0 0.2 2.1 2 0 0 2 2 2 1 HD domain PDEase_I PF00233.19 AIN95575.1 - 0.0002 21.2 0.0 0.00034 20.4 0.0 1.2 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase HDOD PF08668.12 AIN95575.1 - 0.0022 17.5 0.0 0.0039 16.7 0.0 1.3 1 0 0 1 1 1 1 HDOD domain Trm112p PF03966.16 AIN95576.1 - 7e-08 32.9 0.0 2.7e-07 31.0 0.0 1.8 1 1 0 1 1 1 1 Trm112p-like protein zinc_ribbon_5 PF13719.6 AIN95576.1 - 0.057 13.2 1.5 0.49 10.2 0.4 2.4 2 0 0 2 2 2 0 zinc-ribbon domain zinc_ribbon_4 PF13717.6 AIN95576.1 - 0.062 13.2 0.1 0.062 13.2 0.1 1.8 2 0 0 2 2 2 0 zinc-ribbon domain zf-UDP PF14569.6 AIN95576.1 - 0.12 12.5 0.0 0.72 10.0 0.0 2.1 2 0 0 2 2 2 0 Zinc-binding RING-finger Kinesin PF00225.23 AIN95577.1 - 1.7e-69 234.3 0.0 2.3e-69 233.9 0.0 1.1 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 AIN95577.1 - 3.3e-10 40.1 0.0 1.8e-08 34.5 0.0 2.3 2 0 0 2 2 2 1 Microtubule binding EPO_TPO PF00758.18 AIN95577.1 - 0.2 11.7 1.1 1.4 8.9 0.0 2.2 2 0 0 2 2 2 0 Erythropoietin/thrombopoietin FHA PF00498.26 AIN95580.1 - 4.2e-09 36.6 0.0 1.9e-08 34.5 0.0 2.1 1 1 0 1 1 1 1 FHA domain SMP PF04927.12 AIN95580.1 - 1 9.9 9.3 0.049 14.1 2.5 2.5 2 0 0 2 2 2 0 Seed maturation protein DUF4490 PF14892.6 AIN95581.1 - 0.0021 18.1 0.2 0.0039 17.2 0.2 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4490) Leu_zip PF15294.6 AIN95584.1 - 2.9e-13 50.0 10.4 1.2e-06 28.2 1.1 2.4 1 1 1 2 2 2 2 Leucine zipper AAA_10 PF12846.7 AIN95584.1 - 0.087 11.7 1.3 0.11 11.4 0.6 1.5 2 0 0 2 2 2 0 AAA-like domain FAM184 PF15665.5 AIN95584.1 - 0.12 12.2 10.6 0.21 11.3 10.6 1.3 1 0 0 1 1 1 0 Family with sequence similarity 184, A and B Cep57_MT_bd PF06657.13 AIN95584.1 - 0.4 11.2 9.5 1.7 9.1 2.6 3.0 2 1 1 3 3 3 0 Centrosome microtubule-binding domain of Cep57 V-ATPase_G_2 PF16999.5 AIN95584.1 - 0.43 11.0 17.8 0.075 13.5 1.5 2.4 1 1 1 2 2 2 0 Vacuolar (H+)-ATPase G subunit FliJ PF02050.16 AIN95584.1 - 0.46 10.7 18.9 30 4.9 19.4 2.7 1 1 1 2 2 2 0 Flagellar FliJ protein Spc7 PF08317.11 AIN95584.1 - 1.2 8.0 9.6 1.7 7.4 6.9 2.1 1 1 1 2 2 2 0 Spc7 kinetochore protein TMF_TATA_bd PF12325.8 AIN95584.1 - 1.3 9.3 14.3 1.4 9.1 1.6 2.3 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding GAS PF13851.6 AIN95584.1 - 1.8 7.9 12.7 1.4 8.3 7.4 2.2 1 1 0 2 2 2 0 Growth-arrest specific micro-tubule binding DUF1664 PF07889.12 AIN95584.1 - 2.2 8.3 7.4 0.63 10.1 1.2 2.6 2 1 0 3 3 3 0 Protein of unknown function (DUF1664) ZapB PF06005.12 AIN95584.1 - 2.5 8.6 11.4 3.3 8.2 5.9 2.6 2 0 0 2 2 2 0 Cell division protein ZapB Exonuc_VII_L PF02601.15 AIN95584.1 - 3.2 7.2 14.1 2.8 7.4 13.1 1.5 1 1 0 1 1 1 0 Exonuclease VII, large subunit Baculo_PEP_C PF04513.12 AIN95584.1 - 3.3 7.8 8.7 9.4 6.3 3.6 2.9 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus XRN_N PF03159.18 AIN95585.1 - 4.5e-90 301.3 0.0 7.2e-90 300.6 0.0 1.3 1 0 0 1 1 1 1 XRN 5'-3' exonuclease N-terminus XRN_M PF17846.1 AIN95585.1 - 2.9e-84 283.6 3.6 7.9e-55 186.6 1.2 2.4 1 1 1 2 2 2 2 Xrn1 helical domain XRN1_D1 PF18332.1 AIN95585.1 - 1.6e-22 80.2 0.0 2.6e-22 79.5 0.0 1.3 1 0 0 1 1 1 1 Exoribonuclease Xrn1 D1 domain SH3_12 PF18129.1 AIN95585.1 - 2e-16 59.8 0.1 4.7e-16 58.6 0.1 1.7 1 0 0 1 1 1 1 Xrn1 SH3-like domain FHA PF00498.26 AIN95587.1 - 0.0047 17.3 0.0 0.0099 16.2 0.0 1.4 1 0 0 1 1 1 1 FHA domain NIBRIN_BRCT_II PF16508.5 AIN95587.1 - 0.043 14.1 0.0 0.085 13.2 0.0 1.5 1 0 0 1 1 1 0 Second BRCT domain on Nijmegen syndrome breakage protein Yop-YscD_cpl PF16697.5 AIN95587.1 - 0.061 13.6 0.0 0.16 12.3 0.0 1.6 1 0 0 1 1 1 0 Inner membrane component of T3SS, cytoplasmic domain RNase_H PF00075.24 AIN95588.1 - 5e-29 101.3 1.8 2.5e-20 73.1 0.0 3.0 1 1 1 2 2 2 2 RNase H zf-MYND PF01753.18 AIN95589.1 - 1.4e-11 44.3 11.8 1.4e-11 44.3 11.8 2.0 3 0 0 3 3 3 1 MYND finger zf-C6H2 PF15801.5 AIN95589.1 - 0.029 14.7 2.8 0.029 14.7 2.8 2.8 4 0 0 4 4 4 0 zf-MYND-like zinc finger, mRNA-binding DUF4599 PF15371.6 AIN95589.1 - 0.043 14.4 0.9 13 6.4 0.1 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4599) TPR_2 PF07719.17 AIN95591.1 - 0.023 14.8 9.6 0.75 10.1 0.8 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_19 PF14559.6 AIN95591.1 - 0.14 12.6 10.7 0.85 10.2 10.7 2.4 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_1 PF00515.28 AIN95591.1 - 0.32 10.9 4.0 2.4 8.1 0.5 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat Sel1 PF08238.12 AIN95591.1 - 0.79 10.5 4.8 1 10.1 0.2 2.5 2 0 0 2 2 2 0 Sel1 repeat TPR_16 PF13432.6 AIN95591.1 - 1.2 9.9 23.8 0.03 15.0 6.2 4.2 3 0 0 3 3 3 0 Tetratricopeptide repeat HIP1_clath_bdg PF16515.5 AIN95591.1 - 4.4 8.0 12.7 3.1 8.5 9.1 2.4 1 1 1 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Exonuc_VII_L PF02601.15 AIN95591.1 - 4.5 6.7 10.0 13 5.3 9.7 1.9 2 0 0 2 2 2 0 Exonuclease VII, large subunit V_ATPase_I PF01496.19 AIN95591.1 - 6.5 4.5 4.9 9.7 4.0 4.9 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Peptidase_S9 PF00326.21 AIN95592.1 - 7.9e-33 113.7 0.0 1.4e-32 112.9 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Peptidase_S9_N PF02897.15 AIN95592.1 - 1.6e-26 93.1 0.0 2.9e-26 92.2 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase, N-terminal beta-propeller domain 3Beta_HSD PF01073.19 AIN95593.1 - 1.2e-28 99.9 0.0 1.5e-28 99.6 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 AIN95593.1 - 2e-17 63.5 0.0 2.8e-17 63.0 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 AIN95593.1 - 2.8e-10 40.4 0.0 4.1e-10 39.9 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding NAD_binding_4 PF07993.12 AIN95593.1 - 1.8e-08 33.9 0.0 2.5e-08 33.4 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein GDP_Man_Dehyd PF16363.5 AIN95593.1 - 2.6e-05 23.8 0.0 3.8e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 AIN95593.1 - 0.00034 19.8 0.0 0.00054 19.2 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NmrA PF05368.13 AIN95593.1 - 0.024 14.2 0.0 0.038 13.5 0.0 1.2 1 0 0 1 1 1 0 NmrA-like family Gln-synt_C PF00120.24 AIN95595.1 - 2.8e-19 69.3 0.0 7.2e-19 68.0 0.0 1.5 1 1 0 1 1 1 1 Glutamine synthetase, catalytic domain Gln-synt_N PF03951.19 AIN95595.1 - 3.5e-13 49.1 0.0 6.2e-13 48.3 0.0 1.4 1 0 0 1 1 1 1 Glutamine synthetase, beta-Grasp domain SnoaL_3 PF13474.6 AIN95595.1 - 0.17 12.1 0.0 0.34 11.2 0.0 1.4 1 0 0 1 1 1 0 SnoaL-like domain zf_CCCH_4 PF18345.1 AIN95596.1 - 2.6e-06 27.3 2.6 2.6e-06 27.3 2.6 1.8 2 0 0 2 2 2 1 Zinc finger domain zf-CCCH_4 PF18044.1 AIN95596.1 - 3.9e-06 26.5 0.7 9.6e-06 25.3 0.7 1.7 1 0 0 1 1 1 1 CCCH-type zinc finger zf-CCCH PF00642.24 AIN95596.1 - 7.9e-06 25.6 1.7 7.9e-06 25.6 1.7 2.1 2 0 0 2 2 2 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Torus PF16131.5 AIN95596.1 - 0.00055 20.6 0.1 0.0013 19.4 0.1 1.6 1 0 0 1 1 1 1 Torus domain zf-CCCH_2 PF14608.6 AIN95596.1 - 0.022 15.2 1.4 0.061 13.8 1.4 1.8 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger FAF PF11250.8 AIN95597.1 - 0.097 12.9 0.0 0.25 11.6 0.0 1.7 1 0 0 1 1 1 0 Fantastic Four meristem regulator Ribosomal_L19e PF01280.20 AIN95599.1 - 3.8e-60 202.1 11.2 3.8e-60 202.1 11.2 2.1 2 0 0 2 2 2 1 Ribosomal protein L19e Macoilin PF09726.9 AIN95599.1 - 0.35 9.4 15.1 0.37 9.3 15.1 1.1 1 0 0 1 1 1 0 Macoilin family UPF0242 PF06785.11 AIN95599.1 - 1.3 9.1 8.8 1.8 8.6 8.8 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus PepSY_TM_like_2 PF16357.5 AIN95599.1 - 5.1 7.0 6.2 7.8 6.4 6.2 1.3 1 0 0 1 1 1 0 Putative PepSY_TM-like Presenilin PF01080.17 AIN95599.1 - 5.5 5.6 8.3 7.1 5.3 8.3 1.1 1 0 0 1 1 1 0 Presenilin Kinesin PF00225.23 AIN95601.1 - 2.4e-11 43.1 0.1 0.00011 21.2 0.0 2.7 2 0 0 2 2 2 2 Kinesin motor domain DUF3074 PF11274.8 AIN95601.1 - 0.071 13.1 0.0 0.071 13.1 0.0 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF3074) TMF_DNA_bd PF12329.8 AIN95601.1 - 0.47 10.5 10.1 0.099 12.7 4.9 2.4 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding SCAB_CC PF16712.5 AIN95601.1 - 0.57 10.0 12.3 0.7 9.7 8.6 2.3 2 0 0 2 2 2 0 Coiled-coil regions of plant-specific actin-binding protein DUF2730 PF10805.8 AIN95601.1 - 1.7 8.8 6.5 0.51 10.5 2.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2730) UPF0231 PF06062.11 AIN95601.1 - 1.8 8.9 6.1 1.4 9.2 0.3 2.5 1 1 2 3 3 3 0 Uncharacterised protein family (UPF0231) TMPIT PF07851.13 AIN95601.1 - 6 6.0 9.6 3 7.0 6.8 1.8 1 1 0 1 1 1 0 TMPIT-like protein DUF4407 PF14362.6 AIN95601.1 - 6.6 6.0 17.8 0.44 9.9 11.5 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) TPR_12 PF13424.6 AIN95602.1 - 7.6e-07 29.3 1.2 0.00052 20.2 0.4 2.9 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_10 PF13374.6 AIN95602.1 - 5e-05 23.0 3.8 0.04 13.8 0.0 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 AIN95602.1 - 0.00025 20.7 3.0 0.032 14.0 0.0 3.5 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.17 AIN95602.1 - 0.0053 16.8 1.1 0.05 13.7 0.0 3.1 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.6 AIN95602.1 - 0.03 14.3 0.0 6.9 7.0 0.0 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_19 PF14559.6 AIN95602.1 - 0.098 13.2 4.0 0.22 12.0 1.7 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat ABA_WDS PF02496.16 AIN95603.1 - 0.12 12.9 0.2 0.12 12.9 0.2 1.9 2 0 0 2 2 2 0 ABA/WDS induced protein NAD_kinase PF01513.21 AIN95604.1 - 2.1e-10 40.3 0.0 7.3e-10 38.5 0.0 1.9 3 0 0 3 3 3 1 ATP-NAD kinase Cnd2 PF05786.14 AIN95605.1 - 4.6e-27 95.1 1.8 3.5e-17 62.4 0.0 3.2 3 0 0 3 3 3 3 Condensin complex subunit 2 CNDH2_N PF06278.11 AIN95605.1 - 0.026 14.8 0.0 0.056 13.7 0.0 1.5 1 0 0 1 1 1 0 Condensin II complex subunit CAP-H2 or CNDH2, N-terminal SpoU_methylase PF00588.19 AIN95608.1 - 1.8e-14 54.1 0.0 1e-08 35.5 0.0 3.0 3 0 0 3 3 3 2 SpoU rRNA Methylase family SpoU_sub_bind PF08032.12 AIN95608.1 - 1.5e-05 25.1 0.0 0.00024 21.3 0.0 2.3 2 0 0 2 2 2 1 RNA 2'-O ribose methyltransferase substrate binding HHH_3 PF12836.7 AIN95608.1 - 0.14 12.4 0.1 0.26 11.6 0.1 1.4 1 0 0 1 1 1 0 Helix-hairpin-helix motif U-box PF04564.15 AIN95609.1 - 7.5e-12 45.2 0.0 1.4e-11 44.4 0.0 1.4 1 0 0 1 1 1 1 U-box domain LRR_4 PF12799.7 AIN95610.1 - 2.4e-13 50.0 1.8 0.68 10.5 0.0 8.6 9 1 1 10 10 10 5 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 AIN95610.1 - 7.9e-05 22.4 8.0 0.45 10.7 0.1 8.1 8 0 0 8 8 8 1 Leucine Rich repeat LRR_8 PF13855.6 AIN95610.1 - 0.00022 20.9 9.6 5.3 6.9 0.1 8.4 8 2 2 10 10 10 2 Leucine rich repeat Maf_N PF08383.11 AIN95611.1 - 0.11 12.3 0.1 0.11 12.3 0.1 2.0 2 0 0 2 2 2 0 Maf N-terminal region DUF2057 PF09829.9 AIN95611.1 - 0.41 10.8 4.1 3.8 7.6 1.0 2.4 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2057) STAT1_TAZ2bind PF12162.8 AIN95611.1 - 1.4 8.5 2.6 2.6 7.7 0.3 2.4 3 0 0 3 3 3 0 STAT1 TAZ2 binding domain TFIIA PF03153.13 AIN95613.1 - 0.097 12.6 1.4 0.29 11.1 1.4 1.8 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit dUTPase_2 PF08761.11 AIN95614.1 - 6.9e-46 156.4 0.0 9.2e-46 156.0 0.0 1.2 1 0 0 1 1 1 1 dUTPase Mgm101p PF06420.12 AIN95614.1 - 0.064 12.8 0.0 0.1 12.1 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial genome maintenance MGM101 Ribosomal_L23 PF00276.20 AIN95615.1 - 3e-15 56.3 2.9 3e-15 56.3 2.9 2.6 2 1 0 2 2 2 1 Ribosomal protein L23 Ribosomal_L23eN PF03939.13 AIN95615.1 - 0.00018 21.7 7.0 0.00055 20.1 7.0 1.9 1 0 0 1 1 1 1 Ribosomal protein L23, N-terminal domain PHD PF00628.29 AIN95617.1 - 0.00041 20.2 0.7 0.00041 20.2 0.7 1.9 2 0 0 2 2 2 1 PHD-finger zf-RING_2 PF13639.6 AIN95617.1 - 8.4 6.8 7.4 3.2 8.1 2.2 2.4 2 0 0 2 2 2 0 Ring finger domain Pro_CA PF00484.19 AIN95618.1 - 5.3e-41 140.5 5.4 3.9e-40 137.7 3.5 2.3 2 1 0 2 2 2 1 Carbonic anhydrase DUF89 PF01937.19 AIN95619.1 - 3.3e-42 144.7 0.0 2.7e-22 79.2 0.0 4.4 4 0 0 4 4 4 4 Protein of unknown function DUF89 Put_Phosphatase PF06888.12 AIN95619.1 - 5.3e-31 107.8 1.7 4.6e-14 52.4 0.0 3.3 2 1 1 3 3 3 3 Putative Phosphatase HAD PF12710.7 AIN95619.1 - 0.005 17.3 0.1 0.14 12.5 0.1 2.7 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Pkinase PF00069.25 AIN95620.1 - 7.1e-47 160.0 0.0 5.8e-36 124.2 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 AIN95620.1 - 7.2e-31 107.4 0.0 1.5e-22 80.2 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase FHA PF00498.26 AIN95620.1 - 2.3e-09 37.5 0.0 7.7e-09 35.8 0.0 1.9 2 0 0 2 2 2 1 FHA domain PAS PF00989.25 AIN95620.1 - 0.0016 18.4 0.0 0.28 11.2 0.0 2.8 2 0 0 2 2 2 1 PAS fold Kinase-like PF14531.6 AIN95620.1 - 0.0031 16.9 0.0 0.0065 15.8 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 AIN95620.1 - 0.036 12.9 0.0 0.062 12.1 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase SQHop_cyclase_N PF13249.6 AIN95621.1 - 7.9e-46 156.5 0.9 1.5e-40 139.1 0.1 3.9 3 1 1 4 4 4 2 Squalene-hopene cyclase N-terminal domain SQHop_cyclase_C PF13243.6 AIN95621.1 - 1.1e-37 129.9 1.2 6.1e-34 117.6 0.4 2.7 3 0 0 3 3 3 2 Squalene-hopene cyclase C-terminal domain Prenyltrans PF00432.21 AIN95621.1 - 8.4e-25 86.2 14.3 1.2e-09 37.8 0.0 5.4 5 1 0 5 5 5 4 Prenyltransferase and squalene oxidase repeat TED_complement PF07678.14 AIN95621.1 - 0.0023 17.0 0.0 0.0068 15.5 0.0 1.7 2 0 0 2 2 2 1 A-macroglobulin TED domain Pec_lyase PF09492.10 AIN95621.1 - 0.019 14.3 0.0 1.1 8.5 0.0 3.1 2 1 1 3 3 3 0 Pectic acid lyase NDUF_B7 PF05676.13 AIN95624.1 - 0.0001 22.0 3.7 0.00018 21.2 3.7 1.3 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) Cmc1 PF08583.10 AIN95624.1 - 0.00038 20.4 3.7 0.00072 19.5 3.7 1.4 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like CX9C PF16860.5 AIN95624.1 - 0.32 11.0 2.4 1.8 8.7 0.2 2.2 2 0 0 2 2 2 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, CHCH PF06747.13 AIN95624.1 - 1.8 8.8 5.0 3 8.1 5.0 1.4 1 0 0 1 1 1 0 CHCH domain Ctf8 PF09696.10 AIN95625.1 - 9.6e-10 39.0 0.0 0.013 15.8 0.0 3.2 3 0 0 3 3 3 3 Ctf8 CSS-motif PF12792.7 AIN95625.1 - 0.086 12.3 0.0 0.18 11.3 0.0 1.4 1 0 0 1 1 1 0 CSS motif domain associated with EAL AAA_lid_7 PF17867.1 AIN95626.1 - 0.074 13.3 0.2 0.5 10.6 0.2 2.6 1 0 0 1 1 1 0 Midasin AAA lid domain DZR PF12773.7 AIN95626.1 - 4.6 7.4 9.7 1 9.5 0.2 3.1 3 0 0 3 3 3 0 Double zinc ribbon C2 PF00168.30 AIN95627.1 - 1.7e-09 37.9 0.0 3.1e-09 37.1 0.0 1.4 1 0 0 1 1 1 1 C2 domain Ank_2 PF12796.7 AIN95627.1 - 9.1e-08 32.6 0.0 3.7e-07 30.6 0.0 2.0 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 AIN95627.1 - 2.9e-07 30.9 0.1 0.0018 18.8 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 AIN95627.1 - 1.2e-05 25.5 0.4 0.17 12.4 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.6 AIN95627.1 - 8.1e-05 22.8 0.5 0.35 11.3 0.1 2.9 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 AIN95627.1 - 0.014 15.8 0.4 9.3 7.2 0.0 3.2 3 0 0 3 3 3 0 Ankyrin repeat YEATS PF03366.16 AIN95628.1 - 1.1e-15 57.3 0.0 2.1e-15 56.5 0.0 1.4 1 0 0 1 1 1 1 YEATS family PALP PF00291.25 AIN95629.1 - 5.3e-57 193.5 0.3 6e-57 193.3 0.3 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme FAA_hydrolase_N PF09298.11 AIN95630.1 - 1.7 8.9 6.8 0.28 11.4 1.9 2.2 2 0 0 2 2 2 0 Fumarylacetoacetase N-terminal HlyIII PF03006.20 AIN95631.1 - 4.2e-15 56.1 9.5 2.7e-08 33.8 1.6 2.7 2 1 0 2 2 2 2 Haemolysin-III related RRM_1 PF00076.22 AIN95633.1 - 4.6e-25 87.2 0.0 1.2e-13 50.7 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PHM7_cyt PF14703.6 AIN95633.1 - 0.011 16.0 0.0 3.3 7.9 0.0 2.6 2 0 0 2 2 2 0 Cytosolic domain of 10TM putative phosphate transporter Phage_tail_T PF06223.12 AIN95637.1 - 0.0042 17.6 0.3 0.011 16.3 0.1 1.8 2 0 0 2 2 2 1 Minor tail protein T DUF4618 PF15397.6 AIN95637.1 - 0.03 13.7 0.6 2.6 7.4 0.0 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4618) ADIP PF11559.8 AIN95637.1 - 0.035 14.2 7.1 1 9.4 0.1 2.4 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding DUF3377 PF11857.8 AIN95637.1 - 5.2 7.1 5.4 0.39 10.7 0.2 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3377) LNS2 PF08235.13 AIN95638.1 - 3.7e-81 271.9 0.0 5.2e-81 271.4 0.0 1.2 1 0 0 1 1 1 1 LNS2 (Lipin/Ned1/Smp2) Lipin_N PF04571.14 AIN95638.1 - 9.9e-19 67.2 0.0 2.4e-18 65.9 0.0 1.6 1 0 0 1 1 1 1 lipin, N-terminal conserved region Acid_phosphat_B PF03767.14 AIN95638.1 - 0.097 12.2 0.0 0.18 11.4 0.0 1.3 1 0 0 1 1 1 0 HAD superfamily, subfamily IIIB (Acid phosphatase) SUIM_assoc PF16619.5 AIN95638.1 - 0.31 11.1 5.2 1.2 9.3 5.2 2.0 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 Use1 PF09753.9 AIN95639.1 - 0.12 12.1 0.2 0.16 11.6 0.2 1.2 1 0 0 1 1 1 0 Membrane fusion protein Use1 mono-CXXC PF15626.6 AIN95639.1 - 0.43 11.0 3.7 0.25 11.7 0.5 2.2 2 0 0 2 2 2 0 single CXXC unit EF-hand_1 PF00036.32 AIN95640.1 - 0.072 12.7 0.0 0.14 11.8 0.0 1.4 1 0 0 1 1 1 0 EF hand EF-hand_7 PF13499.6 AIN95640.1 - 0.16 12.5 0.0 0.37 11.3 0.0 1.6 1 0 0 1 1 1 0 EF-hand domain pair zinc_ribbon_9 PF14369.6 AIN95640.1 - 0.71 10.2 4.8 2.5 8.5 4.8 2.0 1 0 0 1 1 1 0 zinc-ribbon Thymidylat_synt PF00303.19 AIN95641.1 - 1.5e-108 362.0 0.0 2.3e-108 361.4 0.0 1.2 1 0 0 1 1 1 1 Thymidylate synthase DHFR_1 PF00186.19 AIN95641.1 - 1e-22 80.5 0.0 1e-21 77.3 0.0 2.4 1 1 0 1 1 1 1 Dihydrofolate reductase PrmA PF06325.13 AIN95642.1 - 2.7e-08 33.6 0.0 4.1e-08 33.0 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_25 PF13649.6 AIN95642.1 - 3.7e-06 27.6 0.0 9.6e-06 26.2 0.0 1.8 2 0 0 2 2 1 1 Methyltransferase domain MTS PF05175.14 AIN95642.1 - 2.9e-05 23.7 0.0 5.2e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_16 PF10294.9 AIN95642.1 - 3.4e-05 23.6 0.0 5.3e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 Lysine methyltransferase PCMT PF01135.19 AIN95642.1 - 0.00099 18.9 0.0 0.0016 18.2 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) RrnaAD PF00398.20 AIN95642.1 - 0.0014 17.8 0.0 0.0023 17.0 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Cons_hypoth95 PF03602.15 AIN95642.1 - 0.0016 18.1 0.0 0.0025 17.5 0.0 1.3 1 0 0 1 1 1 1 Conserved hypothetical protein 95 CMAS PF02353.20 AIN95642.1 - 0.0053 16.1 0.0 0.0079 15.5 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Met_10 PF02475.16 AIN95642.1 - 0.0073 16.1 0.0 0.011 15.4 0.0 1.3 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_11 PF08241.12 AIN95642.1 - 0.014 16.0 0.0 0.034 14.8 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.12 AIN95642.1 - 0.017 15.8 0.0 0.042 14.6 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.6 AIN95642.1 - 0.076 12.8 0.0 0.15 11.9 0.0 1.4 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_18 PF12847.7 AIN95642.1 - 0.084 12.8 0.0 0.14 12.0 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Acyl-CoA_dh_1 PF00441.24 AIN95643.1 - 4.5e-47 160.0 3.2 7.1e-47 159.4 3.2 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 AIN95643.1 - 1.5e-28 99.7 0.2 4.2e-28 98.3 0.2 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 AIN95643.1 - 9.5e-26 89.8 0.2 2.6e-25 88.5 0.2 1.8 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 AIN95643.1 - 1.7e-20 73.7 2.0 2.9e-20 72.9 2.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain HpaB_N PF11794.8 AIN95643.1 - 0.053 13.2 0.4 0.37 10.4 0.4 2.4 1 1 0 1 1 1 0 4-hydroxyphenylacetate 3-hydroxylase N terminal Acyl-CoA_dh_1 PF00441.24 AIN95645.1 - 4.5e-47 160.0 3.2 7.1e-47 159.4 3.2 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 AIN95645.1 - 1.5e-28 99.7 0.2 4.2e-28 98.3 0.2 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 AIN95645.1 - 9.5e-26 89.8 0.2 2.6e-25 88.5 0.2 1.8 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 AIN95645.1 - 1.7e-20 73.7 2.0 2.9e-20 72.9 2.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain HpaB_N PF11794.8 AIN95645.1 - 0.053 13.2 0.4 0.37 10.4 0.4 2.4 1 1 0 1 1 1 0 4-hydroxyphenylacetate 3-hydroxylase N terminal PP2C PF00481.21 AIN95646.1 - 2.1e-24 86.6 0.5 1.6e-15 57.5 0.0 3.5 3 0 0 3 3 3 3 Protein phosphatase 2C SpoIIE PF07228.12 AIN95646.1 - 0.069 13.1 0.0 0.19 11.6 0.0 1.7 1 0 0 1 1 1 0 Stage II sporulation protein E (SpoIIE) PTH2 PF01981.16 AIN95647.1 - 2e-44 150.6 0.8 2.8e-44 150.2 0.8 1.2 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase PTH2 Oxidored_FMN PF00724.20 AIN95649.1 - 4.5e-41 141.3 0.0 5.8e-41 140.9 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Pyr_redox_2 PF07992.14 AIN95649.1 - 2.1e-15 56.8 0.0 6.1e-15 55.2 0.0 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 AIN95649.1 - 3e-10 40.2 0.0 9.5e-10 38.6 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 AIN95649.1 - 2e-07 31.4 0.7 0.00057 20.4 0.5 3.5 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 AIN95649.1 - 2.9e-07 29.9 0.4 4.7e-07 29.2 0.4 1.3 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.7 AIN95649.1 - 6.2e-07 29.1 0.0 1.1e-06 28.4 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.14 AIN95649.1 - 1.6e-06 27.1 1.8 5.7e-06 25.3 0.1 2.5 2 1 1 3 3 3 1 HI0933-like protein DAO PF01266.24 AIN95649.1 - 2.3e-06 27.4 0.5 5.2e-06 26.3 0.5 1.6 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 AIN95649.1 - 0.00069 19.0 0.2 0.0053 16.1 0.1 2.3 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 AIN95649.1 - 0.0011 18.1 0.2 0.0017 17.5 0.2 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A Amino_oxidase PF01593.24 AIN95649.1 - 0.003 16.9 0.1 0.0051 16.2 0.1 1.3 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase Thi4 PF01946.17 AIN95649.1 - 0.0036 16.6 0.0 0.0074 15.6 0.0 1.4 1 0 0 1 1 1 1 Thi4 family FAD_binding_3 PF01494.19 AIN95649.1 - 0.0089 15.3 0.1 0.015 14.6 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain ApbA PF02558.16 AIN95649.1 - 0.023 14.3 0.5 0.074 12.7 0.3 2.0 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA 3HCDH_N PF02737.18 AIN95649.1 - 0.037 13.9 0.0 0.099 12.5 0.0 1.7 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_7 PF13241.6 AIN95649.1 - 0.042 14.3 0.2 1.1 9.7 0.0 2.4 2 0 0 2 2 2 0 Putative NAD(P)-binding NAD_Gly3P_dh_N PF01210.23 AIN95649.1 - 0.051 13.6 0.1 0.13 12.2 0.1 1.7 2 0 0 2 2 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus FMO-like PF00743.19 AIN95649.1 - 0.06 11.8 0.1 2.1 6.7 0.0 2.1 2 0 0 2 2 2 0 Flavin-binding monooxygenase-like NAD_binding_9 PF13454.6 AIN95649.1 - 0.073 13.1 0.1 0.2 11.7 0.1 1.7 1 0 0 1 1 1 0 FAD-NAD(P)-binding TLD PF07534.16 AIN95650.1 - 1.6e-08 34.9 0.0 3.5e-05 24.0 0.0 3.2 3 0 0 3 3 3 2 TLD SBP_bac_11 PF13531.6 AIN95650.1 - 0.71 9.6 4.5 0.18 11.6 0.5 1.9 2 0 0 2 2 2 0 Bacterial extracellular solute-binding protein SIS PF01380.22 AIN95651.1 - 5.7e-50 168.6 1.0 6.9e-28 97.1 0.0 2.3 2 0 0 2 2 2 2 SIS domain GATase_6 PF13522.6 AIN95651.1 - 5.6e-16 59.0 0.0 1.1e-15 58.0 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.6 AIN95651.1 - 3.7e-09 36.5 0.0 7.9e-09 35.5 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_4 PF13230.6 AIN95651.1 - 0.00023 20.2 0.0 0.00051 19.0 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferases class-II Mob1_phocein PF03637.17 AIN95652.1 - 2.1e-68 229.6 0.2 2.7e-68 229.3 0.2 1.0 1 0 0 1 1 1 1 Mob1/phocein family Ntox8 PF15545.6 AIN95652.1 - 0.096 12.8 0.0 0.21 11.7 0.0 1.5 1 0 0 1 1 1 0 Bacterial toxin 8 DUF3883 PF13020.6 AIN95653.1 - 2.1e-16 59.7 0.0 3.9e-16 58.9 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3883) LRR_8 PF13855.6 AIN95654.1 - 4.5e-20 71.2 16.6 9.3e-08 31.7 0.7 5.5 5 1 0 5 5 5 4 Leucine rich repeat LRR_4 PF12799.7 AIN95654.1 - 1.8e-09 37.7 15.0 0.37 11.3 0.0 6.7 4 3 4 8 8 8 6 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 AIN95654.1 - 0.0051 16.3 0.4 1 8.9 0.2 2.8 3 0 0 3 3 3 2 Leucine-rich repeat LRR_1 PF00560.33 AIN95654.1 - 0.012 16.1 17.3 57 4.8 0.1 10.0 11 1 0 11 11 11 0 Leucine Rich Repeat GRDP-like PF07173.12 AIN95654.1 - 0.012 16.3 2.4 9.1 6.9 0.0 3.9 3 1 1 4 4 4 0 Glycine-rich domain-containing protein-like LRR_6 PF13516.6 AIN95654.1 - 3.4 8.0 24.8 51 4.3 0.0 8.9 10 0 0 10 10 10 0 Leucine Rich repeat WD40 PF00400.32 AIN95655.1 - 0.017 15.9 0.4 0.24 12.3 0.0 3.2 3 0 0 3 3 3 0 WD domain, G-beta repeat DUF5009 PF16401.5 AIN95655.1 - 0.029 13.9 0.6 0.052 13.0 0.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5009) MHYT PF03707.16 AIN95656.1 - 0.63 10.3 10.0 4 7.7 4.1 2.6 2 1 0 2 2 2 0 Bacterial signalling protein N terminal repeat SET PF00856.28 AIN95657.1 - 1.6e-14 54.6 0.0 3.8e-14 53.4 0.0 1.6 1 1 0 1 1 1 1 SET domain zf-MYND PF01753.18 AIN95657.1 - 0.00017 21.6 10.3 0.00017 21.6 10.3 3.0 3 1 0 3 3 3 1 MYND finger TFIIF_beta PF02270.15 AIN95657.1 - 0.14 12.4 0.0 0.33 11.1 0.0 1.6 1 0 0 1 1 1 0 TFIIF, beta subunit HTH domain G-patch PF01585.23 AIN95659.1 - 1.2e-11 44.3 0.8 1.8e-11 43.7 0.8 1.3 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 AIN95659.1 - 9.4e-07 28.8 0.6 2e-06 27.8 0.6 1.5 1 0 0 1 1 1 1 G-patch domain Kinesin PF00225.23 AIN95660.1 - 6e-60 202.9 0.0 1.7e-59 201.5 0.0 1.7 1 1 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 AIN95660.1 - 3.8e-11 43.1 0.0 1.5e-10 41.2 0.0 2.0 1 1 0 1 1 1 1 Microtubule binding AAA_7 PF12775.7 AIN95660.1 - 0.057 12.9 0.0 0.13 11.8 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_22 PF13401.6 AIN95660.1 - 0.058 13.7 0.4 0.64 10.3 0.0 2.7 2 1 0 2 2 2 0 AAA domain AAA_16 PF13191.6 AIN95660.1 - 0.085 13.2 0.1 0.32 11.4 0.0 2.0 2 0 0 2 2 2 0 AAA ATPase domain DUF2034 PF10356.9 AIN95660.1 - 0.13 11.7 0.1 0.24 10.8 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2034) DUF87 PF01935.17 AIN95660.1 - 0.15 12.1 0.0 0.29 11.2 0.0 1.4 1 0 0 1 1 1 0 Helicase HerA, central domain OmpH PF03938.14 AIN95660.1 - 0.61 10.4 3.2 7.3 6.9 0.1 2.2 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) BRE1 PF08647.11 AIN95660.1 - 0.76 9.9 4.2 0.14 12.3 0.6 1.6 2 0 0 2 2 2 0 BRE1 E3 ubiquitin ligase ATG16 PF08614.11 AIN95660.1 - 1.9 8.7 7.8 1.5 9.0 3.1 2.3 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) Ribosomal_L20 PF00453.18 AIN95661.1 - 0.8 9.8 11.5 3.6 7.7 5.8 3.0 2 0 0 2 2 2 0 Ribosomal protein L20 PLAC9 PF15205.6 AIN95661.1 - 1.4 9.4 3.6 2.5 8.6 0.1 3.0 3 0 0 3 3 3 0 Placenta-specific protein 9 Spc7 PF08317.11 AIN95661.1 - 5.1 5.9 36.1 0.056 12.3 10.7 3.4 2 1 0 3 3 3 0 Spc7 kinetochore protein Thioredoxin PF00085.20 AIN95662.1 - 7e-27 93.4 0.0 8.3e-27 93.2 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 AIN95662.1 - 3.9e-07 30.5 0.0 6.5e-07 29.8 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_7 PF13899.6 AIN95662.1 - 5.6e-05 23.2 0.0 8.8e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin-like OST3_OST6 PF04756.13 AIN95662.1 - 7.1e-05 22.3 0.0 0.0001 21.8 0.0 1.3 1 1 0 1 1 1 1 OST3 / OST6 family, transporter family TraF PF13728.6 AIN95662.1 - 0.00031 20.6 0.0 0.00042 20.2 0.0 1.2 1 0 0 1 1 1 1 F plasmid transfer operon protein Thioredoxin_5 PF13743.6 AIN95662.1 - 0.02 14.6 0.0 2.5 7.8 0.0 2.1 2 0 0 2 2 2 0 Thioredoxin Thioredoxin_8 PF13905.6 AIN95662.1 - 0.064 13.6 0.0 0.55 10.6 0.0 2.1 1 1 1 2 2 2 0 Thioredoxin-like 2OG-FeII_Oxy_2 PF13532.6 AIN95663.1 - 3.9e-08 33.7 0.0 1.1e-06 29.0 0.1 2.1 1 1 1 2 2 2 1 2OG-Fe(II) oxygenase superfamily TEX12 PF15219.6 AIN95663.1 - 0.13 12.6 0.0 0.25 11.7 0.0 1.5 1 0 0 1 1 1 0 Testis-expressed 12 DeoC PF01791.9 AIN95664.1 - 8.2e-14 51.8 8.7 1.1e-13 51.4 8.7 1.1 1 0 0 1 1 1 1 DeoC/LacD family aldolase SNase PF00565.17 AIN95665.1 - 1e-15 58.1 0.0 1.5e-15 57.6 0.0 1.2 1 0 0 1 1 1 1 Staphylococcal nuclease homologue Ada_Zn_binding PF02805.16 AIN95665.1 - 0.025 14.6 0.0 0.072 13.1 0.0 1.7 2 0 0 2 2 2 0 Metal binding domain of Ada Troponin PF00992.20 AIN95666.1 - 0.016 15.5 6.2 0.016 15.5 6.2 5.0 4 2 2 6 6 6 0 Troponin MAD PF05557.13 AIN95666.1 - 0.55 8.5 47.3 0.38 9.1 3.6 3.3 2 1 1 3 3 3 0 Mitotic checkpoint protein CALCOCO1 PF07888.11 AIN95666.1 - 2 7.2 47.8 0.05 12.5 23.0 3.2 2 1 1 3 3 3 0 Calcium binding and coiled-coil domain (CALCOCO1) like DUF5003 PF16394.5 AIN95666.1 - 2.5 7.2 4.8 20 4.2 2.5 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF5003) TACC_C PF05010.14 AIN95666.1 - 5.6 6.7 40.5 3.1 7.5 0.9 3.3 2 1 1 3 3 3 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal DUF3450 PF11932.8 AIN95666.1 - 7.1 5.8 41.6 0.36 10.1 16.3 4.1 2 1 1 4 4 4 0 Protein of unknown function (DUF3450) PIG-X PF08320.12 AIN95669.1 - 1.4e-05 25.1 0.1 0.00081 19.4 0.0 2.1 2 0 0 2 2 2 2 PIG-X / PBN1 WD40 PF00400.32 AIN95670.1 - 2e-06 28.4 3.0 0.00063 20.5 0.3 4.5 5 0 0 5 5 5 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 AIN95670.1 - 3.8e-05 23.9 0.4 0.019 15.2 0.0 3.2 2 2 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain RTT107_BRCT_5 PF16770.5 AIN95671.1 - 1.9e-05 24.5 0.0 3.7e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 Regulator of Ty1 transposition protein 107 BRCT domain BRCT_2 PF16589.5 AIN95671.1 - 0.0069 16.8 0.0 0.021 15.2 0.0 1.8 2 0 0 2 2 2 1 BRCT domain, a BRCA1 C-terminus domain DUF4379 PF14311.6 AIN95672.1 - 2.8e-25 88.4 21.4 8.3e-09 35.7 0.2 4.7 4 0 0 4 4 4 4 Probable Zinc-ribbon domain HypA PF01155.19 AIN95672.1 - 1.8e-05 24.7 13.1 0.071 13.1 0.0 4.5 5 0 0 5 5 5 3 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Zn_ribbon_SprT PF17283.2 AIN95672.1 - 0.02 14.8 3.4 0.02 14.8 3.4 5.4 6 1 1 7 7 7 0 SprT-like zinc ribbon domain NTF2 PF02136.20 AIN95674.1 - 3.4e-16 59.9 0.0 3.9e-16 59.7 0.0 1.0 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain Pkinase PF00069.25 AIN95675.1 - 2.2e-60 204.2 0.0 8.3e-59 199.1 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 AIN95675.1 - 1.4e-32 113.1 0.0 4.4e-23 81.9 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.23 AIN95675.1 - 4.1e-05 23.6 0.1 0.11 12.4 0.0 2.2 1 1 0 2 2 2 2 Phosphotransferase enzyme family Kinase-like PF14531.6 AIN95675.1 - 0.00037 19.9 0.0 0.0018 17.7 0.0 1.9 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 AIN95675.1 - 0.016 14.6 0.0 0.034 13.5 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 AIN95675.1 - 0.067 12.1 0.0 0.093 11.7 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Pox_ser-thr_kin PF05445.11 AIN95675.1 - 0.12 11.3 0.0 0.17 10.8 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Thioredoxin PF00085.20 AIN95676.1 - 1.6e-11 44.1 0.0 2e-11 43.8 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin OST3_OST6 PF04756.13 AIN95676.1 - 0.026 13.9 0.0 0.051 12.9 0.0 1.5 1 1 0 1 1 1 0 OST3 / OST6 family, transporter family PCO_ADO PF07847.12 AIN95681.1 - 7.9e-49 165.8 0.0 9.9e-49 165.5 0.0 1.1 1 0 0 1 1 1 1 PCO_ADO CDO_I PF05995.12 AIN95681.1 - 0.0043 16.4 0.2 1.6 8.0 0.0 2.2 2 0 0 2 2 2 2 Cysteine dioxygenase type I Cupin_2 PF07883.11 AIN95681.1 - 0.09 12.5 0.0 5.9 6.7 0.0 2.9 3 0 0 3 3 3 0 Cupin domain FAD_binding_3 PF01494.19 AIN95682.1 - 4.6e-11 42.5 0.0 4.7e-10 39.2 0.0 2.3 2 1 0 2 2 2 1 FAD binding domain SE PF08491.10 AIN95682.1 - 0.038 13.1 0.0 0.058 12.4 0.0 1.3 1 0 0 1 1 1 0 Squalene epoxidase DUF2956 PF11169.8 AIN95683.1 - 0.018 15.2 0.1 0.66 10.2 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2956) DFF-C PF09033.10 AIN95683.1 - 0.17 11.8 2.9 0.3 11.0 2.5 1.6 2 0 0 2 2 2 0 DNA Fragmentation factor 45kDa, C terminal domain DUF4191 PF13829.6 AIN95683.1 - 0.17 11.2 0.1 1.8 7.9 0.0 2.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4191) BT1 PF03092.16 AIN95684.1 - 5.3e-191 635.4 13.8 6.1e-191 635.2 13.8 1.0 1 0 0 1 1 1 1 BT1 family NiFe_hyd_3_EhaA PF17367.2 AIN95684.1 - 2 8.6 14.4 29 4.9 0.7 3.8 2 1 0 2 2 2 0 NiFe-hydrogenase-type-3 Eha complex subunit A MFS_1 PF07690.16 AIN95684.1 - 3.8 6.4 50.6 0.47 9.3 10.3 3.6 2 2 1 3 3 3 0 Major Facilitator Superfamily Coprogen_oxidas PF01218.18 AIN95685.1 - 6.3e-131 435.5 0.1 7.1e-131 435.3 0.1 1.0 1 0 0 1 1 1 1 Coproporphyrinogen III oxidase Flavodoxin_5 PF12724.7 AIN95686.1 - 6.3e-47 159.4 0.0 9.2e-47 158.9 0.0 1.2 1 0 0 1 1 1 1 Flavodoxin domain Flavodoxin_3 PF12641.7 AIN95686.1 - 0.00068 19.4 0.0 0.001 18.8 0.0 1.2 1 0 0 1 1 1 1 Flavodoxin domain Flavodoxin_1 PF00258.25 AIN95686.1 - 0.068 13.4 0.0 0.1 12.8 0.0 1.3 1 0 0 1 1 1 0 Flavodoxin Cyt-b5 PF00173.28 AIN95687.1 - 6.2e-06 26.3 0.0 7.1e-06 26.1 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain CD225 PF04505.12 AIN95687.1 - 0.11 12.7 0.0 0.15 12.2 0.0 1.2 1 0 0 1 1 1 0 Interferon-induced transmembrane protein YppG PF14179.6 AIN95687.1 - 0.14 12.9 0.0 0.19 12.5 0.0 1.4 1 0 0 1 1 1 0 YppG-like protein ESCRT-II PF05871.12 AIN95688.1 - 0.91 9.8 4.1 0.83 9.9 1.3 2.1 1 1 1 2 2 2 0 ESCRT-II complex subunit ThiF PF00899.21 AIN95689.1 - 1.6e-38 132.4 0.0 2.9e-38 131.6 0.0 1.3 1 0 0 1 1 1 1 ThiF family ATG7_N PF16420.5 AIN95689.1 - 2.9e-27 96.1 0.0 4.5e-27 95.5 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-like modifier-activating enzyme ATG7 N-terminus Shikimate_DH PF01488.20 AIN95689.1 - 0.00017 21.7 0.0 0.0064 16.6 0.0 2.3 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase 2-Hacid_dh_C PF02826.19 AIN95689.1 - 0.11 11.9 0.0 4.1 6.7 0.0 2.3 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Isy1 PF06246.12 AIN95690.1 - 4.6e-24 85.4 13.3 4.5e-23 82.1 13.3 2.3 1 1 0 1 1 1 1 Isy1-like splicing family DOT1 PF08123.13 AIN95691.1 - 1e-21 77.4 0.0 1.6e-21 76.8 0.0 1.2 1 0 0 1 1 1 1 Histone methylation protein DOT1 Methyltransf_25 PF13649.6 AIN95691.1 - 4.6e-05 24.0 0.0 0.00012 22.7 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 AIN95691.1 - 0.0015 19.1 0.0 0.0028 18.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.6 AIN95691.1 - 0.0016 18.4 0.0 0.0026 17.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 AIN95691.1 - 0.0018 18.1 0.0 0.0031 17.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 AIN95691.1 - 0.018 14.4 0.0 0.027 13.8 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase AdoMet_MTase PF07757.13 AIN95691.1 - 0.086 13.2 0.0 0.14 12.5 0.0 1.5 1 0 0 1 1 1 0 Predicted AdoMet-dependent methyltransferase MTS PF05175.14 AIN95691.1 - 0.1 12.2 0.0 0.15 11.6 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_12 PF08242.12 AIN95691.1 - 0.1 13.3 0.0 0.17 12.7 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Adaptin_N PF01602.20 AIN95693.1 - 2.9e-84 283.5 10.4 3.8e-84 283.1 10.4 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 AIN95693.1 - 8.2e-07 29.2 1.4 0.0015 18.6 0.0 2.6 2 0 0 2 2 2 2 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 AIN95693.1 - 0.0037 17.4 0.0 0.13 12.6 0.0 3.5 3 0 0 3 3 3 1 HEAT repeat HEAT_2 PF13646.6 AIN95693.1 - 0.0041 17.5 0.3 1.8 9.0 0.0 3.8 4 0 0 4 4 4 1 HEAT repeats FTSW_RODA_SPOVE PF01098.19 AIN95693.1 - 0.029 13.4 0.3 0.056 12.4 0.3 1.4 1 0 0 1 1 1 0 Cell cycle protein Vitellogenin_N PF01347.22 AIN95693.1 - 0.034 12.5 0.3 0.56 8.5 0.0 2.6 3 0 0 3 3 3 0 Lipoprotein amino terminal region Nipped-B_C PF12830.7 AIN95693.1 - 0.095 12.6 1.1 3 7.8 0.0 2.9 3 0 0 3 3 3 0 Sister chromatid cohesion C-terminus RTP1_C1 PF10363.9 AIN95693.1 - 0.15 12.3 1.0 1.1 9.4 0.2 2.7 2 0 0 2 2 2 0 Required for nuclear transport of RNA pol II C-terminus 1 Cytochrom_C1 PF02167.15 AIN95694.1 - 1.1e-76 257.5 0.0 1.2e-76 257.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome C1 family Met_synt_B12 PF02965.17 AIN95697.1 - 4.7e-104 347.7 0.0 8.3e-104 346.9 0.0 1.4 1 0 0 1 1 1 1 Vitamin B12 dependent methionine synthase, activation domain S-methyl_trans PF02574.16 AIN95697.1 - 1.6e-75 254.3 0.4 5.7e-75 252.6 0.1 2.1 3 0 0 3 3 3 1 Homocysteine S-methyltransferase Pterin_bind PF00809.22 AIN95697.1 - 2.6e-48 164.8 0.2 1.7e-45 155.6 0.2 2.8 2 0 0 2 2 2 2 Pterin binding enzyme B12-binding_2 PF02607.17 AIN95697.1 - 3.3e-24 85.1 0.6 1.3e-23 83.2 0.0 2.4 3 0 0 3 3 3 1 B12 binding domain B12-binding PF02310.19 AIN95697.1 - 1.2e-20 73.7 0.3 4.5e-20 71.9 0.3 2.0 1 0 0 1 1 1 1 B12 binding domain M16C_assoc PF08367.11 AIN95698.1 - 6.5e-24 84.4 0.1 1.3e-23 83.4 0.1 1.5 1 0 0 1 1 1 1 Peptidase M16C associated Peptidase_M16_C PF05193.21 AIN95698.1 - 7.8e-21 74.9 0.0 2.3e-14 53.8 0.0 2.6 2 0 0 2 2 2 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 AIN95698.1 - 1.2e-13 51.3 1.7 3.5e-11 43.3 0.0 2.7 3 0 0 3 3 3 2 Insulinase (Peptidase family M16) Izumo-Ig PF16706.5 AIN95698.1 - 0.092 12.8 0.0 0.24 11.5 0.0 1.6 1 0 0 1 1 1 0 Izumo-like Immunoglobulin domain DUF5403 PF17395.2 AIN95698.1 - 0.14 12.4 0.0 0.44 10.9 0.0 1.8 1 0 0 1 1 1 0 Family of unknown function (DUF5403) EF-hand_1 PF00036.32 AIN95699.1 - 3.4e-26 88.8 5.8 6.4e-07 28.5 0.1 4.9 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 AIN95699.1 - 3.8e-24 84.9 0.1 4.3e-07 30.3 0.2 4.2 3 1 0 3 3 3 3 EF-hand domain pair EF-hand_6 PF13405.6 AIN95699.1 - 1.5e-21 74.5 4.9 0.00015 21.4 0.0 5.2 7 0 0 7 7 7 4 EF-hand domain EF-hand_8 PF13833.6 AIN95699.1 - 4.3e-21 74.5 1.8 8.4e-06 25.6 0.0 4.3 3 1 1 4 4 4 3 EF-hand domain pair EF-hand_5 PF13202.6 AIN95699.1 - 2e-16 58.6 8.7 5.4e-06 25.7 0.0 4.5 5 0 0 5 5 5 3 EF hand EF-hand_4 PF12763.7 AIN95699.1 - 2.5e-06 27.4 0.1 0.11 12.5 0.0 3.6 3 1 1 4 4 4 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 AIN95699.1 - 0.00014 22.1 0.0 0.0045 17.3 0.0 2.7 3 0 0 3 3 3 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_9 PF14658.6 AIN95699.1 - 0.00017 21.8 0.3 1.5 9.2 0.0 3.4 3 1 0 3 3 3 2 EF-hand domain p25-alpha PF05517.12 AIN95699.1 - 0.15 12.2 0.0 18 5.5 0.0 2.5 2 1 0 2 2 2 0 p25-alpha EF-hand_11 PF08976.11 AIN95699.1 - 0.17 12.8 0.4 55 4.7 0.0 3.5 3 1 1 4 4 4 0 EF-hand domain Sec7 PF01369.20 AIN95700.1 - 4.4e-36 124.3 0.0 8.8e-36 123.3 0.0 1.5 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.7 AIN95700.1 - 0.0095 15.9 1.3 0.17 11.8 0.0 3.1 2 0 0 2 2 2 1 Guanine nucleotide exchange factor in Golgi transport N-terminal tRNA_Me_trans PF03054.16 AIN95701.1 - 8.7e-44 149.7 0.0 8.2e-32 110.4 0.0 3.4 3 0 0 3 3 3 3 tRNA methyl transferase NAD_synthase PF02540.17 AIN95701.1 - 0.076 12.1 0.1 0.13 11.4 0.1 1.3 1 0 0 1 1 1 0 NAD synthase DUF1751 PF08551.10 AIN95702.1 - 5.4e-05 23.7 1.0 5.4e-05 23.7 1.0 2.8 2 2 1 3 3 3 1 Eukaryotic integral membrane protein (DUF1751) Rhomboid PF01694.22 AIN95702.1 - 0.038 14.0 2.1 0.069 13.2 1.4 2.0 1 1 1 2 2 2 0 Rhomboid family TssN PF17555.2 AIN95702.1 - 0.2 11.0 0.5 0.31 10.4 0.1 1.5 1 1 0 1 1 1 0 Type VI secretion system, TssN DUF747 PF05346.11 AIN95703.1 - 6.4e-70 236.1 2.1 8.8e-70 235.7 2.1 1.1 1 0 0 1 1 1 1 Eukaryotic membrane protein family PLAC8 PF04749.17 AIN95704.1 - 0.0037 18.3 33.5 0.0067 17.4 33.5 1.7 1 1 0 1 1 1 1 PLAC8 family Pkinase PF00069.25 AIN95705.1 - 4e-49 167.4 0.0 8.2e-49 166.3 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 AIN95705.1 - 1.9e-31 109.3 0.0 4.7e-31 108.0 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 AIN95705.1 - 3.5e-05 23.3 0.0 6.5e-05 22.4 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 AIN95705.1 - 0.012 15.5 0.1 0.012 15.5 0.1 2.5 2 1 0 2 2 2 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 AIN95705.1 - 0.048 12.4 0.0 0.18 10.6 0.0 1.9 2 0 0 2 2 2 0 Fungal protein kinase Pkinase PF00069.25 AIN95706.1 - 8.1e-50 169.6 0.0 5.5e-30 104.6 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 AIN95706.1 - 1.4e-34 119.6 0.0 1e-20 74.1 0.1 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 AIN95706.1 - 0.0029 17.0 0.0 0.2 10.9 0.0 2.3 2 0 0 2 2 2 2 Kinase-like Pkinase_fungal PF17667.1 AIN95706.1 - 0.006 15.4 0.0 0.012 14.5 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 AIN95706.1 - 0.15 11.4 0.3 0.35 10.2 0.3 1.6 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family PTPA PF03095.15 AIN95708.1 - 8.4e-95 317.7 0.0 1e-94 317.4 0.0 1.1 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein PLDc_2 PF13091.6 AIN95709.1 - 4.4e-10 39.6 0.0 6.4e-05 22.9 0.0 3.4 2 2 0 2 2 2 2 PLD-like domain PLDc PF00614.22 AIN95709.1 - 2e-06 27.7 1.5 1.8e-05 24.7 0.1 2.9 2 1 0 2 2 2 1 Phospholipase D Active site motif HNF_C PF09354.10 AIN95709.1 - 6.4 7.9 6.5 0.57 11.3 0.4 2.6 2 1 0 2 2 2 0 HNF3 C-terminal domain CIAPIN1 PF05093.13 AIN95712.1 - 2.2e-14 53.7 16.9 7.6e-11 42.4 4.0 2.2 1 1 1 2 2 2 2 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis Pkinase PF00069.25 AIN95714.1 - 4.2e-39 134.5 0.0 5.9e-15 55.3 0.0 3.9 3 1 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.17 AIN95714.1 - 2.1e-18 66.6 0.0 2.3e-12 46.8 0.0 2.5 2 1 0 2 2 2 2 Protein tyrosine kinase APH PF01636.23 AIN95714.1 - 0.053 13.4 0.0 0.12 12.3 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.14 AIN95714.1 - 0.21 10.9 0.0 0.38 10.1 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 AIN95714.1 - 0.22 10.8 0.0 0.81 8.9 0.0 1.8 2 0 0 2 2 2 0 Kinase-like Homoserine_dh PF00742.19 AIN95715.1 - 1.5e-39 135.7 0.0 2.3e-39 135.1 0.0 1.2 1 0 0 1 1 1 1 Homoserine dehydrogenase Peptidase_M20 PF01546.28 AIN95716.1 - 1.7e-32 112.8 0.0 4.1e-32 111.6 0.0 1.7 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 AIN95716.1 - 3.9e-17 62.1 0.0 6.7e-17 61.4 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain HECT PF00632.25 AIN95717.1 - 8.8e-87 291.4 0.0 1.4e-86 290.8 0.0 1.3 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) C1_2 PF03107.16 AIN95717.1 - 1.4e-06 28.5 8.2 2.7e-06 27.6 7.7 1.8 2 0 0 2 2 2 1 C1 domain ZZ PF00569.17 AIN95717.1 - 0.25 11.2 9.0 0.55 10.1 9.0 1.5 1 0 0 1 1 1 0 Zinc finger, ZZ type UPF0172 PF03665.13 AIN95718.1 - 4.7e-47 160.5 0.0 5.6e-47 160.3 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0172) LRR_4 PF12799.7 AIN95719.1 - 0.0014 19.0 0.2 0.049 14.1 0.4 2.4 1 1 1 2 2 2 2 Leucine Rich repeats (2 copies) Spt20 PF12090.8 AIN95719.1 - 0.068 12.8 6.9 0.19 11.4 6.9 1.7 1 0 0 1 1 1 0 Spt20 family LRR_8 PF13855.6 AIN95719.1 - 0.33 10.8 2.1 1.6 8.6 1.8 2.1 1 1 1 2 2 2 0 Leucine rich repeat Kei1 PF08552.11 AIN95719.1 - 2.2 8.1 3.8 0.49 10.3 0.2 1.7 2 0 0 2 2 2 0 Inositolphosphorylceramide synthase subunit Kei1 Activator_LAG-3 PF11498.8 AIN95719.1 - 2.7 6.9 18.9 0.4 9.6 13.2 2.0 2 0 0 2 2 2 0 Transcriptional activator LAG-3 Flagellar_rod PF05149.12 AIN95720.1 - 2.5e-07 30.5 15.2 2.5e-07 30.5 15.2 2.2 2 0 0 2 2 2 1 Paraflagellar rod protein ABA_GPCR PF12430.8 AIN95722.1 - 9.5e-29 100.4 0.9 9.5e-29 100.4 0.9 2.2 2 0 0 2 2 2 1 Abscisic acid G-protein coupled receptor GPHR_N PF12537.8 AIN95722.1 - 6.3e-07 29.4 0.1 2.5e-06 27.5 0.0 2.0 2 0 0 2 2 2 1 The Golgi pH Regulator (GPHR) Family N-terminal EccE PF11203.8 AIN95722.1 - 4.9 7.6 6.4 0.59 10.5 1.8 1.8 2 0 0 2 2 2 0 Putative type VII ESX secretion system translocon, EccE NUDIX PF00293.28 AIN95723.1 - 5e-06 26.6 0.0 1.2e-05 25.4 0.0 1.6 1 0 0 1 1 1 1 NUDIX domain DEAD PF00270.29 AIN95724.1 - 2.5e-45 154.4 0.0 4.2e-45 153.6 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 AIN95724.1 - 5.6e-29 100.7 0.1 3.3e-28 98.3 0.1 2.2 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 AIN95724.1 - 0.0039 17.2 0.0 0.013 15.5 0.0 1.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_C_2 PF13307.6 AIN95724.1 - 0.057 13.6 0.0 0.094 12.9 0.0 1.3 1 0 0 1 1 1 0 Helicase C-terminal domain Ribosomal_60s PF00428.19 AIN95725.1 - 1.6 9.3 0.0 1.6 9.3 0.0 6.0 3 2 1 4 4 4 0 60s Acidic ribosomal protein DUF1674 PF07896.12 AIN95726.1 - 3.9e-14 52.9 0.0 6.1e-14 52.2 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1674) zf-C3HC4 PF00097.25 AIN95727.1 - 6.7e-07 29.1 8.3 2.2e-06 27.4 8.3 2.0 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 AIN95727.1 - 1.2e-06 28.4 8.2 3e-06 27.1 8.2 1.8 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 AIN95727.1 - 2.8e-06 27.1 9.9 2.8e-06 27.1 9.9 2.4 3 0 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 AIN95727.1 - 3.3e-06 27.3 8.6 3.3e-06 27.3 8.6 3.0 2 0 0 2 2 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 AIN95727.1 - 4.5e-06 26.4 6.8 4.5e-06 26.4 6.8 2.4 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 AIN95727.1 - 3.8e-05 23.7 6.8 0.00011 22.2 6.8 1.9 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 AIN95727.1 - 0.00023 21.1 7.8 0.00023 21.1 7.8 2.5 2 0 0 2 2 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 AIN95727.1 - 0.0004 20.2 6.6 0.0004 20.2 6.6 2.4 2 1 1 3 3 2 1 Prokaryotic RING finger family 4 zf-TRAF_2 PF15965.5 AIN95727.1 - 0.002 18.6 6.3 0.002 18.6 6.3 2.8 2 1 0 2 2 1 1 TRAF-like zinc-finger zf-rbx1 PF12678.7 AIN95727.1 - 0.017 15.4 8.5 0.017 15.4 8.5 3.1 2 1 0 2 2 1 0 RING-H2 zinc finger domain zf-RING_10 PF16685.5 AIN95727.1 - 0.09 12.9 6.9 0.28 11.4 6.9 1.8 1 0 0 1 1 1 0 zinc RING finger of MSL2 U-box PF04564.15 AIN95727.1 - 0.11 12.6 0.9 1.1 9.5 0.0 3.0 4 1 1 5 5 3 0 U-box domain Sina PF03145.16 AIN95727.1 - 0.47 10.4 5.3 0.86 9.5 5.3 1.3 1 0 0 1 1 1 0 Seven in absentia protein family DUF1244 PF06844.11 AIN95727.1 - 0.56 10.4 2.5 0.55 10.4 0.6 1.9 2 0 0 2 2 1 0 Protein of unknown function (DUF1244) zf-Nse PF11789.8 AIN95727.1 - 3.9 7.4 9.3 0.26 11.1 2.7 2.5 3 0 0 3 3 2 0 Zinc-finger of the MIZ type in Nse subunit Rav1p_C PF12234.8 AIN95728.1 - 4.7e-41 140.9 0.1 3.7e-39 134.7 0.1 2.1 1 1 0 1 1 1 1 RAVE protein 1 C terminal EamA PF00892.20 AIN95730.1 - 1.7e-15 57.4 30.6 2.1e-09 37.6 1.2 3.2 3 0 0 3 3 3 3 EamA-like transporter family TPT PF03151.16 AIN95730.1 - 0.00015 21.2 1.4 0.00024 20.6 1.4 1.3 1 0 0 1 1 1 1 Triose-phosphate Transporter family SLC35F PF06027.12 AIN95730.1 - 0.00017 21.2 10.7 0.00038 20.1 10.7 1.6 1 1 0 1 1 1 1 Solute carrier family 35 PUNUT PF16913.5 AIN95730.1 - 0.00049 19.4 0.1 0.00049 19.4 0.1 2.2 2 0 0 2 2 2 1 Purine nucleobase transmembrane transport UAA PF08449.11 AIN95730.1 - 0.0011 18.3 7.2 0.0023 17.2 7.2 1.5 1 0 0 1 1 1 1 UAA transporter family CRT-like PF08627.10 AIN95730.1 - 0.023 13.7 7.5 0.052 12.5 1.0 2.2 2 0 0 2 2 2 0 CRT-like, chloroquine-resistance transporter-like SIN1_PH PF16979.5 AIN95731.1 - 3.2e-08 33.8 0.2 6.9e-08 32.7 0.2 1.5 1 0 0 1 1 1 1 SAPK-interacting protein 1 (Sin1), Pleckstrin-homology MaoC_dehydratas PF01575.19 AIN95733.1 - 1.3e-21 76.4 0.0 1.8e-21 76.0 0.0 1.2 1 0 0 1 1 1 1 MaoC like domain MaoC_dehydrat_N PF13452.6 AIN95733.1 - 5.2e-09 36.3 0.0 8.2e-09 35.7 0.0 1.3 1 0 0 1 1 1 1 N-terminal half of MaoC dehydratase MaoC_dehydratas PF01575.19 AIN95734.1 - 3.2e-22 78.4 0.0 4.1e-22 78.1 0.0 1.1 1 0 0 1 1 1 1 MaoC like domain MaoC_dehydrat_N PF13452.6 AIN95734.1 - 1.4e-11 44.7 0.0 3.5e-11 43.3 0.0 1.7 1 1 1 2 2 2 1 N-terminal half of MaoC dehydratase 4HBT PF03061.22 AIN95734.1 - 0.00052 20.3 0.0 0.0014 19.0 0.0 1.7 1 1 1 2 2 2 1 Thioesterase superfamily 4HBT_2 PF13279.6 AIN95734.1 - 0.079 13.4 0.0 0.12 12.9 0.0 1.3 1 1 0 1 1 1 0 Thioesterase-like superfamily Acyl-CoA_dh_N PF02771.16 AIN95736.1 - 3.4e-10 40.6 0.0 8.3e-10 39.3 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 AIN95736.1 - 3.9e-07 30.2 0.3 9.7e-07 28.9 0.3 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain RIBIOP_C PF04950.12 AIN95737.1 - 2.3e-92 309.6 0.0 4.8e-92 308.5 0.0 1.6 1 0 0 1 1 1 1 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal AARP2CN PF08142.12 AIN95737.1 - 2.4e-18 66.0 0.1 6.3e-18 64.6 0.1 1.8 1 0 0 1 1 1 1 AARP2CN (NUC121) domain MATalpha_HMGbox PF04769.12 AIN95737.1 - 0.015 14.7 0.1 0.035 13.4 0.1 1.5 1 0 0 1 1 1 0 Mating-type protein MAT alpha 1 HMG-box DHC_N2 PF08393.13 AIN95739.1 - 1e-45 156.6 0.0 2.3e-45 155.4 0.0 1.6 1 0 0 1 1 1 1 Dynein heavy chain, N-terminal region 2 AAA_7 PF12775.7 AIN95739.1 - 3.9e-07 29.7 0.0 4.2e-06 26.4 0.0 2.3 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_8 PF12780.7 AIN95739.1 - 0.0098 15.2 0.0 0.02 14.3 0.0 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region D4 AAA_6 PF12774.7 AIN95739.1 - 0.045 12.7 0.0 0.12 11.3 0.0 1.6 2 0 0 2 2 2 0 Hydrolytic ATP binding site of dynein motor region CENP-B_dimeris PF09026.10 AIN95739.1 - 0.13 12.7 0.1 25 5.4 0.0 2.6 2 0 0 2 2 2 0 Centromere protein B dimerisation domain CortBP2 PF09727.9 AIN95739.1 - 0.17 11.8 6.4 0.49 10.3 6.4 1.8 1 0 0 1 1 1 0 Cortactin-binding protein-2 Tugs PF17840.1 AIN95739.1 - 0.43 10.8 2.1 2.7 8.3 0.0 3.4 3 0 0 3 3 3 0 Tethering Ubl4a to BAGS domain CwsA PF10814.8 AIN95739.1 - 0.58 10.3 3.8 3.3 7.9 3.8 2.4 1 0 0 1 1 1 0 Cell wall synthesis protein CwsA HrpB7 PF09486.10 AIN95739.1 - 0.87 10.0 24.1 3.4 8.1 3.6 2.9 2 0 0 2 2 2 0 Bacterial type III secretion protein (HrpB7) DUF3958 PF13125.6 AIN95739.1 - 2 8.6 3.9 1 9.6 0.2 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3958) Golgin_A5 PF09787.9 AIN95739.1 - 2.4 7.6 8.7 0.7 9.3 4.9 1.9 2 0 0 2 2 2 0 Golgin subfamily A member 5 DUF1180 PF06679.12 AIN95740.1 - 0.0055 17.1 0.9 0.0055 17.1 0.9 2.9 4 0 0 4 4 4 1 Protein of unknown function (DUF1180) DUF4611 PF15387.6 AIN95740.1 - 0.32 11.2 4.2 0.67 10.2 4.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) NOA36 PF06524.12 AIN95740.1 - 4.9 6.4 5.5 7.2 5.8 5.5 1.2 1 0 0 1 1 1 0 NOA36 protein Serglycin PF04360.12 AIN95740.1 - 5 7.0 6.4 11 5.9 6.4 1.6 1 0 0 1 1 1 0 Serglycin DNA_pol_phi PF04931.13 AIN95740.1 - 5.1 5.1 6.1 7.1 4.6 6.1 1.1 1 0 0 1 1 1 0 DNA polymerase phi Cwf_Cwc_15 PF04889.12 AIN95740.1 - 5.3 6.7 10.6 0.62 9.7 5.6 1.8 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein Ribosomal_L7Ae PF01248.26 AIN95741.1 - 2.5e-20 72.0 0.2 4.7e-20 71.1 0.2 1.4 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RNase_P_pop3 PF08228.11 AIN95741.1 - 5.7e-05 23.2 0.1 9.3e-05 22.5 0.1 1.3 1 0 0 1 1 1 1 RNase P subunit Pop3 Sec20 PF03908.13 AIN95742.1 - 0.00014 21.7 1.4 0.00052 19.9 0.8 2.1 1 1 1 2 2 2 1 Sec20 V-SNARE_C PF12352.8 AIN95742.1 - 0.0014 18.9 1.2 0.0047 17.2 1.2 1.8 1 0 0 1 1 1 1 Snare region anchored in the vesicle membrane C-terminus ADIP PF11559.8 AIN95742.1 - 1.2 9.2 10.1 0.12 12.4 4.4 2.0 1 1 0 2 2 2 0 Afadin- and alpha -actinin-Binding Atg14 PF10186.9 AIN95742.1 - 4.2 6.3 8.6 34 3.4 8.4 2.0 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Mito_carr PF00153.27 AIN95743.1 - 3.7e-32 110.1 4.0 6.3e-13 48.5 0.3 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein Ras PF00071.22 AIN95746.1 - 1.5e-54 184.0 0.0 1.7e-54 183.8 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 AIN95746.1 - 2.2e-28 98.9 0.0 3.1e-28 98.4 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 AIN95746.1 - 9.4e-10 38.2 0.0 1.2e-09 37.9 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 AIN95746.1 - 0.00054 20.0 0.0 0.00077 19.5 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 AIN95746.1 - 0.00096 18.7 0.0 0.02 14.4 0.0 2.2 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 AIN95746.1 - 0.017 14.5 0.0 0.022 14.1 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region CLP1_P PF16575.5 AIN95748.1 - 6.6e-29 101.0 0.0 2.2e-28 99.4 0.0 1.9 2 0 0 2 2 2 1 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_16 PF13191.6 AIN95748.1 - 0.01 16.2 0.1 0.041 14.3 0.1 2.1 1 0 0 1 1 1 0 AAA ATPase domain MMR_HSR1 PF01926.23 AIN95748.1 - 0.11 12.6 0.1 0.27 11.3 0.1 1.7 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_22 PF13401.6 AIN95748.1 - 0.11 12.8 0.4 0.31 11.3 0.0 2.0 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 AIN95748.1 - 0.12 12.8 0.0 0.23 11.9 0.0 1.4 1 0 0 1 1 1 0 RNA helicase Sel1 PF08238.12 AIN95749.1 - 1.2e-21 76.7 37.7 7.7e-07 29.6 0.1 8.9 9 0 0 9 9 9 6 Sel1 repeat ETF_QO PF05187.13 AIN95750.1 - 2.2e-43 146.6 0.3 4.1e-43 145.8 0.3 1.4 1 0 0 1 1 1 1 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S FAD_binding_2 PF00890.24 AIN95750.1 - 5e-08 32.4 2.5 0.0014 17.8 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.24 AIN95750.1 - 1.5e-07 31.4 3.4 0.00031 20.5 1.1 2.2 1 1 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 AIN95750.1 - 1e-06 28.9 0.1 3.7e-06 27.1 0.1 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 AIN95750.1 - 1.2e-05 24.7 0.1 0.0082 15.4 0.3 2.2 2 0 0 2 2 2 2 Thi4 family Pyr_redox PF00070.27 AIN95750.1 - 0.0001 22.8 0.1 0.21 12.1 0.2 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 AIN95750.1 - 0.00015 21.8 0.1 0.00028 20.9 0.1 1.4 1 0 0 1 1 1 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.14 AIN95750.1 - 0.00026 20.3 0.1 0.00043 19.6 0.1 1.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 AIN95750.1 - 0.0014 17.4 0.4 0.0021 16.8 0.4 1.2 1 0 0 1 1 1 1 HI0933-like protein Trp_halogenase PF04820.14 AIN95750.1 - 0.016 14.0 0.6 0.17 10.7 0.2 2.1 2 0 0 2 2 2 0 Tryptophan halogenase Lycopene_cycl PF05834.12 AIN95750.1 - 0.034 13.2 0.1 0.05 12.7 0.1 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein Pyr_redox_3 PF13738.6 AIN95750.1 - 0.059 12.6 0.2 0.084 12.1 0.2 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 AIN95750.1 - 0.069 12.4 1.2 0.086 12.1 0.2 1.7 2 0 0 2 2 2 0 FAD binding domain FAD_oxidored PF12831.7 AIN95750.1 - 0.084 12.2 0.1 0.14 11.5 0.1 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase NPL PF17800.1 AIN95751.1 - 1e-11 45.3 0.0 2e-11 44.4 0.0 1.5 1 0 0 1 1 1 1 Nucleoplasmin-like domain Filament PF00038.21 AIN95753.1 - 0.00034 20.3 9.3 0.00034 20.3 9.3 3.4 2 1 0 3 3 3 1 Intermediate filament protein SHE3 PF17078.5 AIN95753.1 - 0.014 15.1 18.1 0.45 10.2 2.9 2.6 2 0 0 2 2 2 0 SWI5-dependent HO expression protein 3 eIF3m_C_helix PF18005.1 AIN95753.1 - 0.024 14.3 0.2 2.6 7.8 0.0 2.8 2 0 0 2 2 2 0 eIF3 subunit M, C-terminal helix Fez1 PF06818.15 AIN95753.1 - 0.03 14.8 38.2 0.067 13.6 11.4 2.8 2 1 0 2 2 2 0 Fez1 CBP_CCPA PF17040.5 AIN95753.1 - 0.053 14.1 1.5 0.51 10.9 0.2 2.7 2 0 0 2 2 2 0 Cellulose-complementing protein A UMPH-1 PF05822.12 AIN95753.1 - 0.058 12.9 0.7 0.12 11.8 0.2 1.8 2 0 0 2 2 2 0 Pyrimidine 5'-nucleotidase (UMPH-1) ERM PF00769.19 AIN95753.1 - 0.3 10.9 44.7 0.031 14.1 12.8 3.0 2 1 1 3 3 3 0 Ezrin/radixin/moesin family GAS PF13851.6 AIN95753.1 - 0.99 8.7 38.3 0.084 12.2 9.9 4.0 5 0 0 5 5 5 0 Growth-arrest specific micro-tubule binding SAWADEE PF16719.5 AIN95753.1 - 1.2 9.1 6.6 1.1 9.3 0.5 3.1 2 1 1 3 3 3 0 SAWADEE domain LPP PF04728.13 AIN95753.1 - 1.9 8.9 18.7 8.4 6.9 1.2 5.2 4 0 0 4 4 4 0 Lipoprotein leucine-zipper Ycf54 PF10674.9 AIN95753.1 - 1.9 8.8 4.8 0.98 9.7 0.5 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF2488) DUF4407 PF14362.6 AIN95753.1 - 2.1 7.7 39.0 2 7.7 10.5 3.2 2 1 1 3 3 3 0 Domain of unknown function (DUF4407) DUF3584 PF12128.8 AIN95753.1 - 3.3 5.1 40.9 0.57 7.6 12.9 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) HAP1_N PF04849.13 AIN95753.1 - 5.3 6.2 28.8 0.35 10.0 13.7 2.5 2 0 0 2 2 2 0 HAP1 N-terminal conserved region Cation_ATPase_C PF00689.21 AIN95754.1 - 5.6e-42 143.5 2.1 1.3e-41 142.4 2.1 1.6 1 0 0 1 1 1 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 AIN95754.1 - 4.5e-31 107.8 0.3 2e-30 105.7 0.1 2.2 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.26 AIN95754.1 - 2.7e-13 50.7 0.1 2e-11 44.6 0.1 3.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 AIN95754.1 - 2.3e-12 46.4 0.0 4.4e-12 45.5 0.0 1.5 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Cation_ATPase PF13246.6 AIN95754.1 - 1e-11 44.8 0.0 2.1e-11 43.7 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 AIN95754.1 - 5.4e-06 26.3 0.0 0.00045 20.1 0.1 2.4 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF3935 PF13071.6 AIN95754.1 - 0.059 13.9 1.2 0.26 11.8 0.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3935) LptF_LptG PF03739.14 AIN95754.1 - 0.18 10.7 1.5 0.27 10.0 0.7 1.7 2 0 0 2 2 2 0 Lipopolysaccharide export system permease LptF/LptG JAB PF01398.21 AIN95755.1 - 0.0098 15.9 0.0 0.017 15.1 0.0 1.4 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Cation_ATPase_C PF00689.21 AIN95756.1 - 9.1e-42 142.8 5.3 2e-41 141.7 5.3 1.6 1 0 0 1 1 1 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 AIN95756.1 - 6.3e-31 107.3 0.1 2e-30 105.6 0.1 2.0 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.26 AIN95756.1 - 2.8e-13 50.7 0.1 2e-11 44.6 0.1 3.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 AIN95756.1 - 2e-12 46.6 0.0 4.4e-12 45.5 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Cation_ATPase PF13246.6 AIN95756.1 - 9.1e-12 44.9 0.0 2.2e-11 43.7 0.0 1.6 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 AIN95756.1 - 5.1e-06 26.4 0.0 0.00045 20.0 0.1 2.5 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF3935 PF13071.6 AIN95756.1 - 0.29 11.7 1.9 1 10.0 0.7 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3935) V-SNARE_C PF12352.8 AIN95758.1 - 1.4e-08 34.9 4.8 2.2e-08 34.2 4.8 1.2 1 0 0 1 1 1 1 Snare region anchored in the vesicle membrane C-terminus Prominin PF05478.11 AIN95758.1 - 0.027 12.5 0.4 0.033 12.2 0.4 1.0 1 0 0 1 1 1 0 Prominin Synaptobrevin PF00957.21 AIN95758.1 - 0.063 13.1 1.4 0.13 12.0 1.4 1.7 1 1 0 1 1 1 0 Synaptobrevin S4 PF01479.25 AIN95759.1 - 2.7e-13 49.4 0.3 5.8e-13 48.3 0.3 1.6 1 0 0 1 1 1 1 S4 domain Ribosomal_S4 PF00163.19 AIN95759.1 - 1.1e-07 32.6 0.2 2.3e-07 31.6 0.2 1.8 1 1 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain TyrRSs_C PF16714.5 AIN95759.1 - 0.019 14.7 0.0 0.029 14.2 0.0 1.3 1 0 0 1 1 1 0 Tyrosyl-tRNA synthetase C-terminal domain Pkinase PF00069.25 AIN95760.1 - 3.1e-40 138.2 0.0 4.7e-26 91.7 0.0 3.8 3 1 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.17 AIN95760.1 - 2.4e-22 79.5 0.0 1.1e-15 57.7 0.0 2.9 3 1 0 3 3 3 2 Protein tyrosine kinase NTP_transf_2 PF01909.23 AIN95761.1 - 0.0056 17.0 0.0 0.012 15.9 0.0 1.5 1 0 0 1 1 1 1 Nucleotidyltransferase domain PAP_assoc PF03828.19 AIN95761.1 - 0.0085 16.3 0.0 0.047 13.9 0.0 2.1 2 0 0 2 2 2 1 Cid1 family poly A polymerase EF-hand_1 PF00036.32 AIN95762.1 - 1.7e-26 89.7 9.2 8.5e-09 34.4 0.7 4.5 5 0 0 5 5 5 3 EF hand EF-hand_7 PF13499.6 AIN95762.1 - 9.8e-25 86.8 1.4 1e-12 48.3 1.1 2.9 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_6 PF13405.6 AIN95762.1 - 3.8e-23 79.4 3.7 1.1e-09 37.4 0.1 4.5 5 0 0 5 5 5 3 EF-hand domain EF-hand_8 PF13833.6 AIN95762.1 - 1.4e-17 63.3 9.9 8.3e-12 44.8 1.1 3.7 2 2 2 4 4 4 3 EF-hand domain pair EF-hand_5 PF13202.6 AIN95762.1 - 6.6e-13 47.5 10.6 2e-05 23.9 0.1 4.2 4 0 0 4 4 4 3 EF hand EF-hand_9 PF14658.6 AIN95762.1 - 2.2e-10 40.7 0.1 3.2e-05 24.2 0.0 2.5 3 0 0 3 3 3 2 EF-hand domain EF-hand_4 PF12763.7 AIN95762.1 - 5.4e-06 26.3 0.8 0.016 15.2 0.0 2.6 2 1 1 3 3 3 2 Cytoskeletal-regulatory complex EF hand SUB1_ProdP9 PF18213.1 AIN95762.1 - 0.002 17.9 0.1 0.0033 17.2 0.1 1.4 1 0 0 1 1 1 1 SUB1 protease Prodomain ProdP9 EF-hand_14 PF17959.1 AIN95762.1 - 0.0071 16.7 0.2 2 8.8 0.1 2.5 2 0 0 2 2 2 1 EF-hand domain HEAT PF02985.22 AIN95764.1 - 2.6e-07 30.3 22.8 0.0074 16.5 0.6 10.5 11 0 0 11 11 11 2 HEAT repeat HEAT_2 PF13646.6 AIN95764.1 - 3.4e-07 30.5 23.8 0.00095 19.5 0.1 7.7 6 2 0 8 8 8 3 HEAT repeats CLASP_N PF12348.8 AIN95764.1 - 9.9e-06 25.3 0.1 0.052 13.1 0.0 3.2 2 0 0 2 2 2 2 CLASP N terminal Cnd1 PF12717.7 AIN95764.1 - 6.6e-05 23.0 0.0 0.014 15.4 0.0 3.7 4 0 0 4 4 4 1 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 AIN95764.1 - 0.0037 17.7 3.9 0.013 16.0 1.0 10.8 7 4 3 12 12 12 3 HEAT-like repeat DUF3437 PF11919.8 AIN95764.1 - 0.0098 15.8 1.5 0.079 12.9 0.1 3.2 1 1 1 2 2 2 1 Domain of unknown function (DUF3437) Vac14_Fab1_bd PF12755.7 AIN95764.1 - 0.031 14.9 0.1 0.63 10.7 0.0 3.4 3 0 0 3 3 3 0 Vacuolar 14 Fab1-binding region IBN_N PF03810.19 AIN95764.1 - 0.069 13.1 0.0 0.38 10.7 0.0 2.4 2 0 0 2 2 2 0 Importin-beta N-terminal domain YdaT_toxin PF06254.11 AIN95764.1 - 0.074 13.6 0.1 3 8.5 0.0 3.1 2 0 0 2 2 2 0 Putative bacterial toxin ydaT HEAT_PBS PF03130.16 AIN95764.1 - 1.2 10.0 7.3 50 5.0 0.0 5.7 4 1 1 5 5 5 0 PBS lyase HEAT-like repeat MCD PF05292.11 AIN95765.1 - 5.8e-62 209.6 0.0 4.3e-40 137.9 0.0 3.0 2 1 0 2 2 2 2 Malonyl-CoA decarboxylase C-terminal domain PPI_Ypi1 PF07491.11 AIN95767.1 - 2.3e-14 52.9 2.9 4.8e-14 51.9 2.9 1.6 1 1 0 1 1 1 1 Protein phosphatase inhibitor DnaJ PF00226.31 AIN95768.1 - 1.9e-05 24.7 0.0 5.3e-05 23.3 0.0 1.8 1 1 0 1 1 1 1 DnaJ domain His_Phos_1 PF00300.22 AIN95769.1 - 2.7e-28 99.0 0.1 3.1e-23 82.5 0.0 2.5 2 0 0 2 2 2 2 Histidine phosphatase superfamily (branch 1) 6PF2K PF01591.18 AIN95769.1 - 1.1e-14 54.3 0.4 2.6e-10 40.0 0.0 3.3 3 0 0 3 3 3 3 6-phosphofructo-2-kinase AAA_33 PF13671.6 AIN95769.1 - 0.058 13.5 1.3 0.34 11.1 0.0 2.8 4 0 0 4 4 4 0 AAA domain DnaJ PF00226.31 AIN95770.1 - 9.2e-05 22.5 0.0 0.00021 21.3 0.0 1.6 1 0 0 1 1 1 1 DnaJ domain DnaJ PF00226.31 AIN95771.1 - 4.2e-07 30.0 0.1 9.6e-07 28.8 0.1 1.6 1 0 0 1 1 1 1 DnaJ domain Pam16 PF03656.13 AIN95771.1 - 0.017 15.1 0.0 0.04 13.9 0.0 1.5 1 0 0 1 1 1 0 Pam16 Comm PF15957.5 AIN95771.1 - 0.066 13.6 0.0 0.12 12.7 0.0 1.4 1 0 0 1 1 1 0 Commissureless TFIIB PF00382.19 AIN95771.1 - 0.081 13.0 0.0 0.57 10.3 0.0 2.3 2 0 0 2 2 2 0 Transcription factor TFIIB repeat RRM_1 PF00076.22 AIN95773.1 - 0.003 17.3 0.0 0.0056 16.5 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PGM_PMM_I PF02878.16 AIN95774.1 - 6.4e-13 48.6 0.0 1.5e-09 37.7 0.0 2.4 2 0 0 2 2 2 2 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_IV PF00408.20 AIN95774.1 - 7.1e-10 38.9 0.2 1.8e-09 37.6 0.2 1.7 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain PGM_PMM_III PF02880.16 AIN95774.1 - 0.0079 16.4 0.1 0.016 15.4 0.1 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.16 AIN95774.1 - 0.028 15.0 0.3 0.65 10.6 0.1 3.0 2 1 0 2 2 2 0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II UQ_con PF00179.26 AIN95776.1 - 2.7e-39 134.0 0.0 4.2e-39 133.4 0.0 1.4 1 1 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 AIN95776.1 - 0.1 12.3 0.0 0.14 11.9 0.0 1.2 1 0 0 1 1 1 0 Prokaryotic E2 family B RRM_1 PF00076.22 AIN95778.1 - 0.028 14.2 0.1 3.5 7.5 0.0 2.5 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Pkinase PF00069.25 AIN95779.1 - 1.7e-51 175.2 0.0 2.9e-51 174.4 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 AIN95779.1 - 1.6e-35 122.7 0.0 4.4e-34 117.9 0.0 2.8 1 1 0 1 1 1 1 Protein tyrosine kinase PX PF00787.24 AIN95779.1 - 0.0024 17.8 0.0 0.0048 16.9 0.0 1.5 1 0 0 1 1 1 1 PX domain Kinase-like PF14531.6 AIN95779.1 - 0.054 12.8 0.0 0.094 12.0 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Pkinase_fungal PF17667.1 AIN95779.1 - 0.23 10.2 0.0 0.41 9.4 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase Glyco_transf_10 PF00852.19 AIN95780.1 - 4.7e-16 59.0 0.0 1e-08 35.1 0.0 3.3 3 0 0 3 3 3 3 Glycosyltransferase family 10 (fucosyltransferase) C-term Sirohm_synth_C PF14823.6 AIN95780.1 - 0.11 12.2 0.1 0.26 10.9 0.1 1.6 1 0 0 1 1 1 0 Sirohaem biosynthesis protein C-terminal Pkinase PF00069.25 AIN95782.1 - 4.1e-77 259.1 0.0 4.8e-77 258.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 AIN95782.1 - 2.7e-39 135.0 0.0 3.2e-39 134.8 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 AIN95782.1 - 2.1e-11 43.7 0.0 5.1e-09 35.9 0.0 2.1 1 1 1 2 2 2 2 Kinase-like Kdo PF06293.14 AIN95782.1 - 0.00023 20.6 0.3 0.00038 19.9 0.3 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 AIN95782.1 - 0.00032 19.8 0.2 0.00044 19.3 0.2 1.2 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 AIN95782.1 - 0.005 16.8 0.2 0.19 11.6 0.1 2.2 1 1 0 2 2 2 1 Phosphotransferase enzyme family IML1 PF12257.8 AIN95783.1 - 3.3e-38 131.5 0.0 1e-28 100.3 0.0 3.2 2 1 0 2 2 2 2 Vacuolar membrane-associated protein Iml1 Radial_spoke PF04712.12 AIN95784.1 - 9.6e-05 21.5 8.7 0.008 15.2 7.4 2.8 2 1 0 2 2 2 1 Radial spokehead-like protein CENP-B_dimeris PF09026.10 AIN95784.1 - 0.003 17.9 2.2 0.0051 17.2 2.2 1.3 1 0 0 1 1 1 1 Centromere protein B dimerisation domain Myc_N PF01056.18 AIN95784.1 - 0.051 13.5 0.7 0.067 13.1 0.7 1.1 1 0 0 1 1 1 0 Myc amino-terminal region Nucleo_P87 PF07267.11 AIN95784.1 - 0.58 8.9 1.4 0.76 8.6 1.4 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 NOA36 PF06524.12 AIN95784.1 - 3.4 6.9 7.5 5.7 6.2 7.5 1.3 1 0 0 1 1 1 0 NOA36 protein Ribosomal_60s PF00428.19 AIN95784.1 - 4 8.1 12.7 7.5 7.2 12.7 1.4 1 0 0 1 1 1 0 60s Acidic ribosomal protein DUF3437 PF11919.8 AIN95785.1 - 1.7e-17 63.1 0.0 6.9e-17 61.1 0.0 2.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3437) NPL PF17800.1 AIN95789.1 - 2.8e-14 53.5 0.0 3.8e-14 53.1 0.0 1.2 1 0 0 1 1 1 1 Nucleoplasmin-like domain DUF2541 PF10807.8 AIN95789.1 - 0.13 12.4 0.0 0.44 10.6 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2541) NPL PF17800.1 AIN95790.1 - 3.1e-16 59.8 0.1 3.1e-16 59.8 0.1 2.4 2 1 0 2 2 2 1 Nucleoplasmin-like domain Presenilin PF01080.17 AIN95790.1 - 6.9 5.3 7.4 11 4.7 7.4 1.3 1 0 0 1 1 1 0 Presenilin NPL PF17800.1 AIN95791.1 - 7e-12 45.8 0.0 7e-12 45.8 0.0 2.5 2 1 0 2 2 2 1 Nucleoplasmin-like domain FeS_assembly_P PF01883.19 AIN95792.1 - 1.9e-09 37.6 0.0 5.2e-09 36.2 0.0 1.7 1 1 0 1 1 1 1 Iron-sulfur cluster assembly protein Glyco_hydro_1 PF00232.18 AIN95792.1 - 0.035 12.5 0.0 0.035 12.5 0.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 1 PIF1 PF05970.14 AIN95793.1 - 2.8e-42 145.2 0.0 1.3e-33 116.7 0.0 2.8 3 0 0 3 3 3 2 PIF1-like helicase AAA_30 PF13604.6 AIN95793.1 - 1.6e-14 54.0 0.0 2.9e-14 53.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain Herpes_Helicase PF02689.14 AIN95793.1 - 1.3e-09 36.6 3.0 2.9e-06 25.5 0.1 2.1 2 0 0 2 2 2 2 Helicase AAA_19 PF13245.6 AIN95793.1 - 2.3e-09 37.7 0.0 6.7e-09 36.2 0.0 1.8 1 1 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 AIN95793.1 - 3.4e-05 23.7 0.0 0.00036 20.3 0.0 2.7 2 1 0 2 2 2 1 Viral (Superfamily 1) RNA helicase AAA_22 PF13401.6 AIN95793.1 - 0.00021 21.6 0.0 0.00051 20.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 AIN95793.1 - 0.00022 21.1 0.2 0.18 11.6 0.0 3.3 2 1 0 3 3 3 1 AAA domain AAA_5 PF07728.14 AIN95793.1 - 0.0029 17.6 0.0 0.0082 16.1 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) T2SSE PF00437.20 AIN95793.1 - 0.0034 16.5 0.1 0.0069 15.5 0.1 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_7 PF12775.7 AIN95793.1 - 0.013 15.0 0.0 0.024 14.2 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_16 PF13191.6 AIN95793.1 - 0.015 15.7 0.2 0.039 14.3 0.2 1.6 1 0 0 1 1 1 0 AAA ATPase domain Mg_chelatase PF01078.21 AIN95793.1 - 0.033 13.6 0.0 0.061 12.7 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI UvrD_C_2 PF13538.6 AIN95793.1 - 0.036 13.9 0.1 0.13 12.1 0.1 2.0 1 1 0 1 1 1 0 UvrD-like helicase C-terminal domain ABC_tran PF00005.27 AIN95793.1 - 0.085 13.4 0.1 0.17 12.4 0.1 1.4 1 0 0 1 1 1 0 ABC transporter SH3_13 PF18335.1 AIN95793.1 - 0.096 12.5 0.0 0.21 11.5 0.0 1.4 1 0 0 1 1 1 0 ATP-dependent RecD-like DNA helicase SH3 domain NACHT PF05729.12 AIN95793.1 - 0.11 12.5 0.0 0.21 11.5 0.0 1.5 1 0 0 1 1 1 0 NACHT domain Rotamase PF00639.21 AIN95794.1 - 4.4e-20 72.5 0.0 4.9e-20 72.3 0.0 1.0 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_3 PF13616.6 AIN95794.1 - 3.6e-15 56.5 0.0 4.4e-15 56.2 0.0 1.1 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_2 PF13145.6 AIN95794.1 - 0.028 15.3 0.0 0.035 15.0 0.0 1.1 1 0 0 1 1 1 0 PPIC-type PPIASE domain Sel1 PF08238.12 AIN95796.1 - 0.0004 21.0 3.4 1.9 9.3 2.8 3.4 2 1 0 2 2 2 2 Sel1 repeat E1-E2_ATPase PF00122.20 AIN95797.1 - 1.1e-22 80.4 0.0 5.1e-22 78.3 0.0 2.2 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.26 AIN95797.1 - 5.7e-12 46.4 2.4 5.4e-05 23.6 0.8 2.8 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 AIN95797.1 - 0.0015 18.6 0.0 0.0037 17.3 0.0 1.7 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 AIN95797.1 - 0.02 14.6 0.3 0.059 13.1 0.1 1.9 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase Glyco_hydr_116N PF12215.8 AIN95797.1 - 0.18 11.3 0.1 0.36 10.3 0.1 1.4 1 0 0 1 1 1 0 beta-glucosidase 2, glycosyl-hydrolase family 116 N-term Cation_ATPase_C PF00689.21 AIN95797.1 - 1.6 8.4 18.6 0.053 13.2 9.5 2.8 2 1 0 2 2 2 0 Cation transporting ATPase, C-terminus Dpy-30 PF05186.13 AIN95798.1 - 9.7e-12 44.4 0.0 1.6e-11 43.7 0.0 1.4 1 0 0 1 1 1 1 Dpy-30 motif HPP PF04982.13 AIN95798.1 - 0.054 13.7 0.2 0.068 13.4 0.2 1.1 1 0 0 1 1 1 0 HPP family BPL_LplA_LipB PF03099.19 AIN95799.1 - 6.1e-08 32.6 0.0 2.1e-07 30.9 0.0 1.9 1 1 0 1 1 1 1 Biotin/lipoate A/B protein ligase family zf-C2H2 PF00096.26 AIN95800.1 - 1.4e-07 31.6 8.1 0.00029 21.1 1.0 2.5 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 AIN95800.1 - 6.6e-07 29.6 8.0 0.0068 17.1 0.6 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_3rep PF18868.1 AIN95800.1 - 0.00014 22.6 0.0 0.26 12.0 0.0 2.3 2 0 0 2 2 2 2 Zinc finger C2H2-type, 3 repeats zf-C2H2_6 PF13912.6 AIN95800.1 - 0.00064 19.6 6.6 0.059 13.4 0.6 2.4 2 0 0 2 2 2 2 C2H2-type zinc finger DUF629 PF04780.12 AIN95800.1 - 0.0023 16.5 0.9 0.93 7.9 0.2 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF629) zf-Di19 PF05605.12 AIN95800.1 - 0.0065 16.7 1.5 0.52 10.6 0.3 2.6 2 0 0 2 2 2 1 Drought induced 19 protein (Di19), zinc-binding PHD_Oberon PF07227.11 AIN95800.1 - 0.011 15.6 0.7 0.46 10.4 0.1 2.3 2 0 0 2 2 2 0 PHD - plant homeodomain finger protein zf_C2H2_ZHX PF18387.1 AIN95800.1 - 0.019 14.6 1.6 4.7 6.9 0.1 2.3 2 0 0 2 2 2 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-trcl PF13451.6 AIN95800.1 - 0.032 14.1 1.7 1.1 9.3 0.1 2.3 2 0 0 2 2 2 0 Probable zinc-ribbon domain zf-C2H2_2 PF12756.7 AIN95800.1 - 0.043 14.2 4.9 0.49 10.8 0.3 2.3 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-met PF12874.7 AIN95800.1 - 0.058 13.8 4.3 0.1 13.1 1.1 2.5 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-H2C2_2 PF13465.6 AIN95800.1 - 0.064 13.7 3.3 8.1 7.1 0.2 3.1 2 0 0 2 2 2 0 Zinc-finger double domain Zn-ribbon_8 PF09723.10 AIN95800.1 - 0.066 13.3 1.2 1.3 9.2 0.1 2.4 2 0 0 2 2 2 0 Zinc ribbon domain zf_UBZ PF18439.1 AIN95800.1 - 0.068 12.8 0.9 4.5 6.9 0.1 2.5 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger CpXC PF14353.6 AIN95800.1 - 0.094 12.8 1.4 8.4 6.5 0.0 2.2 2 0 0 2 2 2 0 CpXC protein Actin_micro PF17003.5 AIN95800.1 - 0.15 11.2 0.1 3.5 6.7 0.0 2.0 2 0 0 2 2 2 0 Putative actin-like family TFIIS_C PF01096.18 AIN95800.1 - 0.16 11.8 4.3 2.6 8.0 0.3 2.6 2 0 0 2 2 2 0 Transcription factor S-II (TFIIS) OrsD PF12013.8 AIN95800.1 - 0.38 11.2 2.1 1.7 9.1 0.1 2.2 2 0 0 2 2 2 0 Orsellinic acid/F9775 biosynthesis cluster protein D zf-LYAR PF08790.11 AIN95800.1 - 0.61 10.0 3.1 15 5.6 0.4 2.9 3 0 0 3 3 2 0 LYAR-type C2HC zinc finger zf-met2 PF12907.7 AIN95800.1 - 1.1 9.5 7.4 0.1 12.8 1.8 2.2 2 0 0 2 2 2 0 Zinc-binding zf-C2H2_jaz PF12171.8 AIN95800.1 - 1.3 9.4 6.2 0.77 10.1 0.7 2.7 3 0 0 3 3 2 0 Zinc-finger double-stranded RNA-binding Coatomer_WDAD PF04053.14 AIN95801.1 - 0.016 14.3 0.1 0.034 13.2 0.1 1.5 1 0 0 1 1 1 0 Coatomer WD associated region PQQ_2 PF13360.6 AIN95801.1 - 0.69 9.4 6.1 1.3 8.5 0.2 3.0 3 0 0 3 3 3 0 PQQ-like domain FAM76 PF16046.5 AIN95801.1 - 2 7.7 13.1 3.9 6.7 13.1 1.5 1 0 0 1 1 1 0 FAM76 protein BLOC1_2 PF10046.9 AIN95801.1 - 4.9 7.5 11.1 2.3 8.6 3.8 3.2 3 0 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 FlaC_arch PF05377.11 AIN95801.1 - 8 6.9 8.7 29 5.1 0.1 3.7 4 1 0 4 4 4 0 Flagella accessory protein C (FlaC) FA_desaturase PF00487.24 AIN95802.1 - 1.8e-38 132.8 24.3 1.8e-38 132.8 24.3 1.4 1 1 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.28 AIN95802.1 - 0.016 15.3 0.0 0.034 14.3 0.0 1.5 1 0 0 1 1 1 0 Cytochrome b5-like Heme/Steroid binding domain Dus PF01207.17 AIN95803.1 - 0.021 13.9 0.2 0.031 13.4 0.2 1.2 1 0 0 1 1 1 0 Dihydrouridine synthase (Dus) VWA_2 PF13519.6 AIN95805.1 - 9e-13 48.8 0.2 1.1e-11 45.3 0.0 2.4 1 1 1 2 2 2 1 von Willebrand factor type A domain UIM PF02809.20 AIN95805.1 - 0.00012 21.7 4.8 0.00012 21.7 4.8 3.5 3 0 0 3 3 3 2 Ubiquitin interaction motif VWA PF00092.28 AIN95805.1 - 0.012 15.8 0.1 0.02 15.1 0.1 1.3 1 0 0 1 1 1 0 von Willebrand factor type A domain Ssl1 PF04056.14 AIN95805.1 - 0.039 13.8 0.0 0.056 13.3 0.0 1.2 1 0 0 1 1 1 0 Ssl1-like EF-hand_1 PF00036.32 AIN95806.1 - 0.16 11.6 0.2 0.75 9.5 0.0 2.2 2 0 0 2 2 2 0 EF hand PMSR PF01625.21 AIN95807.1 - 4.6e-52 176.3 0.4 5.7e-52 175.9 0.4 1.1 1 0 0 1 1 1 1 Peptide methionine sulfoxide reductase Chorein_N PF12624.7 AIN95808.1 - 9.7e-07 28.9 0.0 9.3e-06 25.8 0.0 2.6 3 0 0 3 3 3 1 N-terminal region of Chorein or VPS13 VPS13_C PF16909.5 AIN95808.1 - 0.0019 18.0 0.0 0.0052 16.6 0.0 1.6 1 0 0 1 1 1 1 Vacuolar-sorting-associated 13 protein C-terminal Aa_trans PF01490.18 AIN95809.1 - 9.6e-59 199.1 22.0 1.1e-58 198.9 22.0 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 AIN95809.1 - 8.9e-10 38.1 8.2 8.9e-10 38.1 8.2 2.1 2 0 0 2 2 2 1 Tryptophan/tyrosine permease family Galactosyl_T PF01762.21 AIN95810.1 - 0.0011 18.8 0.1 0.0016 18.3 0.1 1.2 1 0 0 1 1 1 1 Galactosyltransferase SMC_N PF02463.19 AIN95811.1 - 2.5e-60 203.7 1.7 3.3e-60 203.3 1.7 1.1 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 AIN95811.1 - 1.9e-22 79.8 0.0 5.8e-22 78.2 0.0 1.9 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_15 PF13175.6 AIN95811.1 - 2.7e-17 63.6 5.2 7.8e-14 52.2 2.0 2.9 2 1 0 2 2 2 2 AAA ATPase domain AAA_23 PF13476.6 AIN95811.1 - 8.9e-16 59.0 2.2 8.9e-16 59.0 2.2 4.9 2 2 1 3 3 1 1 AAA domain AAA_21 PF13304.6 AIN95811.1 - 6.2e-14 52.5 3.4 4.5e-06 26.7 0.0 3.3 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 AIN95811.1 - 0.0052 16.5 0.0 0.012 15.3 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain Myb_DNA-binding PF00249.31 AIN95811.1 - 0.077 13.2 1.1 0.4 10.9 1.1 2.3 1 0 0 1 1 1 0 Myb-like DNA-binding domain RsgA_GTPase PF03193.16 AIN95811.1 - 0.22 11.4 1.9 11 5.8 0.0 3.2 2 0 0 2 2 2 0 RsgA GTPase Pro_dh-DNA_bdg PF14850.6 AIN95811.1 - 0.43 11.1 4.4 1.7 9.2 0.4 3.7 3 0 0 3 3 3 0 DNA-binding domain of Proline dehydrogenase ABC_tran PF00005.27 AIN95811.1 - 0.49 10.9 20.1 0.18 12.3 0.4 5.2 3 2 0 3 3 2 0 ABC transporter IL5 PF02025.15 AIN95811.1 - 0.62 10.4 3.4 12 6.3 0.4 3.2 3 0 0 3 3 3 0 Interleukin 5 ChuX_HutX PF06228.13 AIN95812.1 - 0.12 12.2 0.0 0.19 11.5 0.0 1.3 1 0 0 1 1 1 0 Haem utilisation ChuX/HutX Synaptobrevin PF00957.21 AIN95813.1 - 8.2e-31 105.6 4.5 1.5e-30 104.8 4.5 1.5 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.6 AIN95813.1 - 0.02 14.9 0.0 0.041 13.9 0.0 1.5 1 0 0 1 1 1 0 Regulated-SNARE-like domain FtsK_SpoIIIE PF01580.18 AIN95813.1 - 0.039 13.3 0.2 0.059 12.7 0.2 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family DUF4844 PF16133.5 AIN95813.1 - 0.044 14.3 1.0 0.09 13.3 0.6 1.8 2 1 0 2 2 2 0 Domain of unknown function (DUF4844) His_Phos_1 PF00300.22 AIN95816.1 - 6.6e-36 123.8 0.0 7.2e-36 123.7 0.0 1.0 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) ASCH PF04266.14 AIN95817.1 - 1.6e-16 60.8 0.0 5.4e-16 59.1 0.0 1.9 1 0 0 1 1 1 1 ASCH domain zf-C2HC5 PF06221.13 AIN95817.1 - 8e-05 22.5 9.9 0.00019 21.3 9.9 1.6 1 0 0 1 1 1 1 Putative zinc finger motif, C2HC5-type DEAD PF00270.29 AIN95818.1 - 2.1e-37 128.6 0.0 3.7e-37 127.8 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 AIN95818.1 - 3.7e-23 82.0 0.0 1.1e-22 80.4 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 AIN95818.1 - 2.8e-05 24.2 0.0 5.4e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 AIN95818.1 - 5.4e-05 23.5 0.0 0.00019 21.7 0.0 2.0 1 0 0 1 1 1 1 AAA domain SecA_DEAD PF07517.14 AIN95818.1 - 0.018 14.4 0.0 0.11 11.7 0.0 2.1 1 1 0 1 1 1 0 SecA DEAD-like domain GFRP PF06399.13 AIN95818.1 - 0.089 12.7 0.0 0.96 9.4 0.0 2.7 3 0 0 3 3 3 0 GTP cyclohydrolase I feedback regulatory protein (GFRP) Adaptin_N PF01602.20 AIN95819.1 - 9.2e-81 272.0 0.6 1.5e-80 271.3 0.1 1.5 2 0 0 2 2 2 1 Adaptin N terminal region Cnd1 PF12717.7 AIN95819.1 - 3.5e-10 40.2 0.1 3e-06 27.4 0.0 2.4 1 1 1 2 2 2 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 AIN95819.1 - 0.00046 20.5 0.9 1.6 9.2 0.3 3.9 2 1 1 3 3 3 2 HEAT repeats RTP1_C1 PF10363.9 AIN95819.1 - 0.0066 16.6 0.1 0.037 14.2 0.1 2.2 2 0 0 2 2 2 1 Required for nuclear transport of RNA pol II C-terminus 1 Vac14_Fab1_bd PF12755.7 AIN95819.1 - 0.007 16.9 0.1 0.16 12.6 0.0 2.5 2 0 0 2 2 2 1 Vacuolar 14 Fab1-binding region HEAT PF02985.22 AIN95819.1 - 0.01 16.0 8.5 0.54 10.7 0.1 5.0 5 0 0 5 5 5 0 HEAT repeat Arm_2 PF04826.13 AIN95819.1 - 0.023 14.2 0.1 0.047 13.2 0.1 1.5 1 0 0 1 1 1 0 Armadillo-like HEAT_EZ PF13513.6 AIN95819.1 - 0.036 14.6 1.4 5.7 7.5 0.0 3.7 3 0 0 3 3 3 0 HEAT-like repeat Cnd3 PF12719.7 AIN95819.1 - 0.053 12.7 0.3 0.11 11.7 0.3 1.5 1 0 0 1 1 1 0 Nuclear condensing complex subunits, C-term domain DSPc PF00782.20 AIN95820.1 - 1.2e-27 96.3 0.1 2.5e-27 95.3 0.1 1.5 1 1 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase2 PF03162.13 AIN95820.1 - 0.014 15.0 0.0 1.9 8.0 0.0 2.8 3 0 0 3 3 3 0 Tyrosine phosphatase family Init_tRNA_PT PF04179.12 AIN95820.1 - 0.039 14.2 0.0 0.088 13.1 0.0 1.5 1 0 0 1 1 1 0 Rit1 DUSP-like domain Y_phosphatase PF00102.27 AIN95820.1 - 0.087 12.4 0.0 0.14 11.8 0.0 1.3 1 0 0 1 1 1 0 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 AIN95820.1 - 0.15 12.2 0.0 0.28 11.3 0.0 1.4 1 0 0 1 1 1 0 Inositol hexakisphosphate RRM_1 PF00076.22 AIN95820.1 - 0.16 11.8 0.0 0.45 10.4 0.0 1.7 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) BLOC1_2 PF10046.9 AIN95821.1 - 0.017 15.4 4.2 0.017 15.4 4.2 2.9 2 1 1 3 3 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 SCP-1 PF05483.12 AIN95821.1 - 0.018 13.1 10.1 0.029 12.4 10.1 1.2 1 0 0 1 1 1 0 Synaptonemal complex protein 1 (SCP-1) Macoilin PF09726.9 AIN95821.1 - 0.11 11.0 8.4 0.19 10.3 8.4 1.3 1 0 0 1 1 1 0 Macoilin family NPV_P10 PF05531.12 AIN95821.1 - 0.21 12.0 4.8 7.7 7.1 0.2 2.9 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF4407 PF14362.6 AIN95821.1 - 0.22 10.9 12.4 0.38 10.1 12.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) CENP-K PF11802.8 AIN95821.1 - 0.41 10.2 8.8 0.81 9.2 8.8 1.5 1 0 0 1 1 1 0 Centromere-associated protein K CENP-Q PF13094.6 AIN95821.1 - 0.47 10.6 15.5 0.5 10.6 13.4 2.0 2 0 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit CorA PF01544.18 AIN95821.1 - 0.68 9.2 8.7 1.2 8.4 8.7 1.4 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein Cnn_1N PF07989.11 AIN95821.1 - 0.7 10.1 11.3 0.5 10.6 7.5 2.5 1 1 1 2 2 2 0 Centrosomin N-terminal motif 1 GAS PF13851.6 AIN95821.1 - 0.74 9.1 16.6 0.14 11.5 10.6 2.3 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding HALZ PF02183.18 AIN95821.1 - 1.7 9.0 10.3 0.12 12.6 0.5 3.2 3 0 0 3 3 3 0 Homeobox associated leucine zipper TMPIT PF07851.13 AIN95821.1 - 2.1 7.5 7.5 2.3 7.4 6.4 1.4 1 1 0 1 1 1 0 TMPIT-like protein Seryl_tRNA_N PF02403.22 AIN95821.1 - 4.6 7.5 11.3 6.7 7.0 9.3 2.2 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain DUF4140 PF13600.6 AIN95821.1 - 4.6 7.7 17.5 0.35 11.4 4.0 3.5 2 1 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) TetR_C_1 PF02909.17 AIN95821.1 - 4.6 7.0 6.6 1.9 8.3 0.7 3.1 3 1 0 3 3 3 0 Tetracyclin repressor-like, C-terminal domain Rootletin PF15035.6 AIN95821.1 - 6.9 6.6 18.9 1.4 8.9 13.2 2.0 1 1 1 2 2 2 0 Ciliary rootlet component, centrosome cohesion PRKG1_interact PF15898.5 AIN95821.1 - 8 7.4 21.4 4.1 8.4 17.0 2.8 2 1 1 3 3 3 0 cGMP-dependent protein kinase interacting domain YabA PF06156.13 AIN95821.1 - 8.6 7.1 10.2 24 5.6 6.3 2.7 1 1 1 2 2 2 0 Initiation control protein YabA FYVE_2 PF02318.16 AIN95823.1 - 0.13 12.5 9.4 0.25 11.6 9.4 1.3 1 0 0 1 1 1 0 FYVE-type zinc finger ERCC4 PF02732.15 AIN95824.1 - 6.1e-14 52.5 0.0 1.1e-13 51.6 0.0 1.5 1 0 0 1 1 1 1 ERCC4 domain PIG-H PF10181.9 AIN95825.1 - 1.3e-10 41.0 0.3 2.2e-10 40.2 0.3 1.4 1 0 0 1 1 1 1 GPI-GlcNAc transferase complex, PIG-H component DUF3995 PF13160.6 AIN95825.1 - 0.22 11.9 6.2 0.71 10.2 0.4 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3995) LRR_4 PF12799.7 AIN95827.1 - 1.6e-05 25.1 13.5 0.57 10.7 0.2 6.7 6 1 2 8 8 8 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 AIN95827.1 - 5.6e-05 22.8 4.2 0.4 10.5 0.0 4.6 4 1 1 5 5 5 3 Leucine rich repeat RACo_linker PF17650.1 AIN95827.1 - 0.15 11.9 0.3 1.9 8.4 0.1 2.6 2 0 0 2 2 2 0 RACo linker region Hexapep PF00132.24 AIN95828.1 - 4.4e-15 54.7 4.7 0.00016 21.2 1.5 3.3 2 1 1 3 3 3 3 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 AIN95828.1 - 0.00078 19.1 0.7 0.00078 19.1 0.7 2.5 4 0 0 4 4 4 1 Hexapeptide repeat of succinyl-transferase Beta_helix PF13229.6 AIN95828.1 - 0.12 12.2 0.1 0.19 11.6 0.1 1.3 1 0 0 1 1 1 0 Right handed beta helix region Peptidase_C7 PF01830.18 AIN95829.1 - 0.007 15.8 1.5 0.0086 15.5 1.5 1.2 1 0 0 1 1 1 1 Peptidase C7 family Exo_endo_phos PF03372.23 AIN95830.1 - 2.2e-13 50.3 0.0 3.7e-13 49.5 0.0 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family DUF3301 PF11743.8 AIN95830.1 - 0.084 12.6 0.2 2 8.2 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3301) Exo_endo_phos_2 PF14529.6 AIN95830.1 - 0.13 12.1 0.0 0.42 10.5 0.0 2.0 1 1 0 1 1 1 0 Endonuclease-reverse transcriptase ThiF PF00899.21 AIN95832.1 - 1.2e-54 185.2 0.0 1.4e-53 181.7 0.0 2.5 2 1 0 2 2 2 1 ThiF family UAE_UbL PF14732.6 AIN95832.1 - 1.6e-15 57.5 0.0 2.7e-15 56.7 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain UBA_e1_thiolCys PF10585.9 AIN95832.1 - 1.1e-06 28.8 0.0 0.014 15.3 0.0 2.4 2 0 0 2 2 2 2 Ubiquitin-activating enzyme active site ABC1 PF03109.16 AIN95833.1 - 9e-27 93.6 0.0 2.3e-26 92.3 0.0 1.7 2 0 0 2 2 2 1 ABC1 family APH PF01636.23 AIN95833.1 - 0.0024 17.8 4.3 0.0032 17.4 0.1 2.9 3 1 0 4 4 4 1 Phosphotransferase enzyme family Pkinase PF00069.25 AIN95833.1 - 0.032 13.6 0.0 0.11 11.8 0.0 1.8 2 0 0 2 2 2 0 Protein kinase domain DUF3689 PF12463.8 AIN95833.1 - 0.05 12.9 0.0 0.085 12.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3689) Ribosomal_L9_N PF01281.19 AIN95834.1 - 9.7e-07 28.3 0.0 1.7e-06 27.5 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L9, N-terminal domain JHY PF15261.6 AIN95836.1 - 1.4e-09 38.7 1.5 0.0012 19.5 1.1 2.7 2 0 0 2 2 2 2 Jhy protein Ribosomal_L2_C PF03947.18 AIN95838.1 - 1.6e-20 73.5 0.1 2.9e-20 72.8 0.1 1.4 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Sod_Fe_C PF02777.18 AIN95839.1 - 1.5e-35 121.4 0.6 2.7e-35 120.6 0.1 1.7 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.22 AIN95839.1 - 1.2e-20 73.8 1.1 2.3e-20 72.9 0.8 1.7 1 1 1 2 2 2 1 Iron/manganese superoxide dismutases, alpha-hairpin domain Isochorismatase PF00857.20 AIN95840.1 - 1.2e-12 48.4 0.0 4.5e-12 46.5 0.0 1.8 1 1 0 1 1 1 1 Isochorismatase family Isochorismatase PF00857.20 AIN95841.1 - 4.8e-09 36.6 0.1 4.8e-09 36.6 0.1 2.3 3 1 1 4 4 4 1 Isochorismatase family Isochorismatase PF00857.20 AIN95842.1 - 1.6e-11 44.7 0.1 6.1e-11 42.8 0.1 1.8 1 1 0 1 1 1 1 Isochorismatase family zf-Tim10_DDP PF02953.15 AIN95843.1 - 2.6e-11 43.0 0.2 4.5e-11 42.2 0.2 1.3 1 0 0 1 1 1 1 Tim10/DDP family zinc finger APG6 PF04111.12 AIN95850.1 - 5.6e-15 55.8 0.0 9.1e-06 25.7 0.0 3.6 3 1 0 3 3 3 3 Apg6 BARA domain WD40 PF00400.32 AIN95851.1 - 1e-24 86.3 16.1 4.7e-06 27.2 0.0 10.4 9 1 1 10 10 10 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 AIN95851.1 - 1.5e-14 54.0 0.3 0.0031 17.8 0.0 6.1 3 1 2 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain PQQ_2 PF13360.6 AIN95851.1 - 8.5e-06 25.5 0.2 0.00084 19.0 0.1 3.4 2 1 0 2 2 2 1 PQQ-like domain Nup160 PF11715.8 AIN95851.1 - 0.00021 20.1 3.7 1.7 7.2 0.0 4.4 3 2 1 4 4 4 3 Nucleoporin Nup120/160 BBS2_Mid PF14783.6 AIN95851.1 - 0.00064 19.7 0.1 0.89 9.6 0.0 4.5 6 0 0 6 6 6 1 Ciliary BBSome complex subunit 2, middle region PHTB1_N PF14727.6 AIN95851.1 - 0.074 12.4 0.1 3.7 6.8 0.0 3.2 3 1 0 3 3 3 0 PTHB1 N-terminus TPR_14 PF13428.6 AIN95851.1 - 1.3 10.0 5.4 36 5.6 0.0 5.0 4 1 0 4 4 4 0 Tetratricopeptide repeat CDC45 PF02724.14 AIN95852.1 - 1.9 6.7 7.8 3.3 5.9 7.8 1.2 1 0 0 1 1 1 0 CDC45-like protein Linker_histone PF00538.19 AIN95853.1 - 0.68 10.3 0.0 0.68 10.3 0.0 2.4 3 0 0 3 3 3 0 linker histone H1 and H5 family Peptidase_S24 PF00717.23 AIN95855.1 - 7.8e-10 38.6 0.0 1.3e-09 37.9 0.0 1.4 1 0 0 1 1 1 1 Peptidase S24-like Rad60-SLD PF11976.8 AIN95857.1 - 3e-25 87.8 0.1 3.7e-25 87.5 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 AIN95857.1 - 7.2e-12 44.9 0.0 8.7e-12 44.6 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin family HTH_41 PF14502.6 AIN95857.1 - 0.1 12.3 0.2 0.39 10.4 0.0 2.1 2 0 0 2 2 2 0 Helix-turn-helix domain TUG-UBL1 PF11470.8 AIN95857.1 - 0.12 12.7 0.0 0.16 12.2 0.0 1.2 1 0 0 1 1 1 0 TUG ubiquitin-like domain GlgS PF08971.11 AIN95858.1 - 0.15 12.1 0.1 0.27 11.3 0.1 1.3 1 0 0 1 1 1 0 Glycogen synthesis protein TPR_9 PF13371.6 AIN95858.1 - 0.82 9.9 3.7 1.4 9.1 0.0 2.7 3 0 0 3 3 3 0 Tetratricopeptide repeat Metal_resist PF13801.6 AIN95858.1 - 9.2 6.5 10.2 0.28 11.4 1.6 2.5 2 1 1 3 3 3 0 Heavy-metal resistance Pribosyl_synth PF14572.6 AIN95861.1 - 6.1e-20 72.0 1.1 6.1e-20 72.0 1.1 2.4 2 0 0 2 2 2 1 Phosphoribosyl synthetase-associated domain Pribosyltran_N PF13793.6 AIN95861.1 - 9.3e-19 67.5 0.8 2.6e-18 66.0 0.0 2.1 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase SPX PF03105.19 AIN95861.1 - 2.5e-06 27.7 0.4 1.3e-05 25.3 0.2 1.9 2 0 0 2 2 2 1 SPX domain Pribosyltran PF00156.27 AIN95861.1 - 0.03 13.9 0.3 0.45 10.0 0.1 2.6 3 0 0 3 3 3 0 Phosphoribosyl transferase domain Pkinase_Tyr PF07714.17 AIN95862.1 - 3.1e-07 29.9 0.0 0.012 14.9 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 AIN95862.1 - 1.3e-05 24.7 0.0 0.14 11.5 0.0 2.5 2 0 0 2 2 2 2 Protein kinase domain Kelch_1 PF01344.25 AIN95862.1 - 0.0049 16.4 0.1 1.1 8.9 0.0 3.7 3 0 0 3 3 3 1 Kelch motif Kelch_3 PF13415.6 AIN95862.1 - 0.015 15.6 0.1 0.5 10.7 0.0 4.0 3 0 0 3 3 3 0 Galactose oxidase, central domain KCNQ2_u3 PF16642.5 AIN95862.1 - 0.032 15.2 0.2 0.032 15.2 0.2 4.1 4 0 0 4 4 4 0 Unstructured region on Potassium channel subunit alpha KvLQT2 Pkinase PF00069.25 AIN95863.1 - 1.3e-36 126.3 0.0 8.2e-13 48.3 0.0 3.2 3 0 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.17 AIN95863.1 - 1.2e-16 60.7 0.0 3.5e-05 23.2 0.0 3.3 3 0 0 3 3 3 3 Protein tyrosine kinase APH PF01636.23 AIN95863.1 - 0.0062 16.5 0.7 0.84 9.5 0.0 3.6 3 0 0 3 3 3 1 Phosphotransferase enzyme family Amnionless PF14828.6 AIN95863.1 - 0.088 11.6 0.1 0.15 10.9 0.1 1.2 1 0 0 1 1 1 0 Amnionless Complex1_LYR PF05347.15 AIN95864.1 - 0.0016 18.5 0.9 0.0098 15.9 0.8 2.2 2 0 0 2 2 2 1 Complex 1 protein (LYR family) CMAS PF02353.20 AIN95865.1 - 5e-74 249.0 0.6 7.1e-74 248.5 0.6 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_25 PF13649.6 AIN95865.1 - 2e-17 63.7 0.0 4.8e-17 62.5 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 AIN95865.1 - 2.4e-13 50.6 0.0 5.9e-13 49.3 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 AIN95865.1 - 4.2e-12 46.2 0.0 7.9e-12 45.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 AIN95865.1 - 1.4e-08 35.4 0.0 5.1e-08 33.6 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.14 AIN95865.1 - 7.7e-06 25.6 0.0 4.4e-05 23.1 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_31 PF13847.6 AIN95865.1 - 1.9e-05 24.5 0.0 3.7e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain NodS PF05401.11 AIN95865.1 - 0.00063 19.4 0.0 0.001 18.8 0.0 1.3 1 0 0 1 1 1 1 Nodulation protein S (NodS) MetW PF07021.12 AIN95865.1 - 0.0012 18.5 0.0 0.0022 17.6 0.0 1.4 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_32 PF13679.6 AIN95865.1 - 0.0016 18.5 0.0 0.0026 17.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.19 AIN95865.1 - 0.0024 18.0 0.0 0.0039 17.3 0.0 1.4 1 0 0 1 1 1 1 FtsJ-like methyltransferase PCMT PF01135.19 AIN95865.1 - 0.0072 16.1 0.0 0.013 15.2 0.0 1.4 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) RrnaAD PF00398.20 AIN95865.1 - 0.0073 15.4 0.0 0.013 14.6 0.0 1.3 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase TehB PF03848.14 AIN95865.1 - 0.015 14.7 0.0 0.027 13.9 0.0 1.3 1 0 0 1 1 1 0 Tellurite resistance protein TehB eIF-5_eIF-2B PF01873.17 AIN95866.1 - 3.5e-29 101.1 0.7 6.8e-29 100.1 0.7 1.5 1 0 0 1 1 1 1 Domain found in IF2B/IF5 Cytochrom_c3_2 PF14537.6 AIN95866.1 - 0.057 13.9 0.4 0.21 12.1 0.4 1.9 1 0 0 1 1 1 0 Cytochrome c3 DUF1970 PF09301.10 AIN95866.1 - 0.11 12.7 0.4 0.25 11.6 0.4 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1970) Img2 PF05046.14 AIN95867.1 - 3.8e-06 27.1 0.0 6.5e-06 26.3 0.0 1.4 1 0 0 1 1 1 1 Mitochondrial large subunit ribosomal protein (Img2) PRIMA1 PF16101.5 AIN95868.1 - 0.0077 16.3 0.5 0.015 15.3 0.5 1.4 1 0 0 1 1 1 1 Proline-rich membrane anchor 1 Mtp PF03821.16 AIN95869.1 - 0.016 14.8 0.0 0.023 14.3 0.0 1.2 1 0 0 1 1 1 0 Golgi 4-transmembrane spanning transporter Amastin PF07344.11 AIN95870.1 - 7.2e-54 181.8 15.7 8.5e-54 181.6 15.7 1.0 1 0 0 1 1 1 1 Amastin surface glycoprotein Saf_2TM PF18303.1 AIN95871.1 - 0.017 14.7 0.0 0.02 14.5 0.0 1.2 1 0 0 1 1 1 0 SAVED-fused 2TM effector domain DUF4199 PF13858.6 AIN95871.1 - 0.019 15.4 0.1 0.02 15.3 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4199) Polysacc_synt PF01943.17 AIN95871.1 - 0.019 14.3 0.0 0.03 13.7 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein OATP PF03137.20 AIN95871.1 - 0.035 12.4 0.0 0.038 12.3 0.0 1.0 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family TssO PF17561.2 AIN95871.1 - 0.068 13.3 0.2 0.11 12.6 0.2 1.3 1 0 0 1 1 1 0 Type VI secretion system, TssO DUF1279 PF06916.13 AIN95871.1 - 0.07 13.7 0.1 0.098 13.2 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1279) MAP17 PF15807.5 AIN95871.1 - 0.17 12.1 0.0 0.24 11.6 0.0 1.3 1 0 0 1 1 1 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 Amastin PF07344.11 AIN95874.1 - 4e-05 23.5 4.7 4e-05 23.5 4.7 1.9 2 0 0 2 2 2 1 Amastin surface glycoprotein Monooxygenase_B PF04744.12 AIN95874.1 - 0.15 10.8 0.0 0.24 10.2 0.0 1.3 1 0 0 1 1 1 0 Monooxygenase subunit B protein Pox_A14 PF05767.12 AIN95874.1 - 0.33 11.1 2.7 0.27 11.4 0.2 2.0 2 0 0 2 2 2 0 Poxvirus virion envelope protein A14 DnaJ PF00226.31 AIN95875.1 - 3.7e-16 59.0 1.4 7.4e-16 58.0 1.4 1.5 1 0 0 1 1 1 1 DnaJ domain Amastin PF07344.11 AIN95876.1 - 3.6e-52 176.3 9.8 4.3e-52 176.1 9.8 1.1 1 0 0 1 1 1 1 Amastin surface glycoprotein AAA_16 PF13191.6 AIN95877.1 - 0.00017 22.0 0.0 0.00022 21.7 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 AIN95877.1 - 0.0011 19.2 0.0 0.0028 17.9 0.0 1.8 2 1 0 2 2 2 1 AAA domain AAA PF00004.29 AIN95877.1 - 0.0039 17.6 0.0 0.0068 16.8 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 AIN95877.1 - 0.004 17.7 0.0 0.0087 16.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 AIN95877.1 - 0.0048 17.1 0.1 0.011 16.0 0.0 1.7 2 1 0 2 2 2 1 AAA domain Rad17 PF03215.15 AIN95877.1 - 0.011 15.7 0.0 0.016 15.2 0.0 1.2 1 0 0 1 1 1 0 Rad17 P-loop domain ATPase_2 PF01637.18 AIN95877.1 - 0.014 15.4 0.0 0.021 14.8 0.0 1.2 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea Adeno_IVa2 PF02456.15 AIN95877.1 - 0.017 13.9 0.0 0.025 13.4 0.0 1.1 1 0 0 1 1 1 0 Adenovirus IVa2 protein Zeta_toxin PF06414.12 AIN95877.1 - 0.038 13.3 0.1 0.12 11.7 0.0 1.7 1 1 0 1 1 1 0 Zeta toxin SMC_N PF02463.19 AIN95877.1 - 0.085 12.3 0.0 0.12 11.8 0.0 1.2 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain ABC_tran PF00005.27 AIN95877.1 - 0.086 13.4 0.0 0.18 12.3 0.0 1.4 1 1 0 1 1 1 0 ABC transporter Viral_helicase1 PF01443.18 AIN95877.1 - 0.14 11.9 0.0 0.2 11.4 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase DUF815 PF05673.13 AIN95877.1 - 0.17 11.0 0.0 0.22 10.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_29 PF13555.6 AIN95877.1 - 0.22 11.3 0.0 0.42 10.4 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Amastin PF07344.11 AIN95878.1 - 2.6e-55 186.5 6.2 3e-55 186.3 6.2 1.0 1 0 0 1 1 1 1 Amastin surface glycoprotein DUF2165 PF09933.9 AIN95878.1 - 0.02 14.9 0.6 0.043 13.9 0.6 1.5 1 0 0 1 1 1 0 Predicted small integral membrane protein (DUF2165) TIC20 PF16166.5 AIN95878.1 - 0.036 13.8 0.8 0.057 13.2 0.8 1.3 1 0 0 1 1 1 0 Chloroplast import apparatus Tic20-like Claudin_2 PF13903.6 AIN95878.1 - 0.04 13.7 3.9 0.078 12.7 4.0 1.6 1 1 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction Amastin PF07344.11 AIN95879.1 - 5.9e-54 182.1 13.7 6.9e-54 181.9 13.7 1.0 1 0 0 1 1 1 1 Amastin surface glycoprotein ECSCR PF15820.5 AIN95879.1 - 4.4 7.2 0.0 4.4 7.2 0.0 2.9 3 1 0 3 3 3 0 Endothelial cell-specific chemotaxis regulator GRP PF07172.11 AIN95880.1 - 2.5 8.8 6.6 0.26 12.0 0.3 2.2 2 0 0 2 2 2 0 Glycine rich protein family CotJB PF12652.7 AIN95881.1 - 0.021 15.0 5.1 0.39 11.0 3.3 3.1 2 1 0 2 2 2 0 CotJB protein Terminase_4 PF05119.12 AIN95881.1 - 0.15 12.5 0.9 0.45 11.0 0.3 2.1 2 0 0 2 2 2 0 Phage terminase, small subunit SET PF00856.28 AIN95882.1 - 1.2e-09 38.8 0.0 5e-08 33.5 0.0 3.0 1 1 0 1 1 1 1 SET domain DNA_pol_B_thumb PF14791.6 AIN95883.1 - 9e-21 73.8 0.0 1.9e-20 72.8 0.0 1.6 1 0 0 1 1 1 1 DNA polymerase beta thumb DNA_pol_B_palm PF14792.6 AIN95883.1 - 1.3e-17 64.0 0.0 3.1e-17 62.8 0.0 1.7 1 0 0 1 1 1 1 DNA polymerase beta palm HHH_8 PF14716.6 AIN95883.1 - 7.4e-15 55.1 0.4 3.9e-13 49.6 0.1 2.5 2 0 0 2 2 2 1 Helix-hairpin-helix domain DNA_pol_lambd_f PF10391.9 AIN95883.1 - 2.8e-13 49.5 0.1 2.6e-12 46.4 0.0 2.6 3 0 0 3 3 3 1 Fingers domain of DNA polymerase lambda HHH_5 PF14520.6 AIN95883.1 - 7.7e-06 26.4 0.9 0.0021 18.6 0.0 2.8 1 1 2 3 3 3 2 Helix-hairpin-helix domain HHH_3 PF12836.7 AIN95883.1 - 0.016 15.5 0.1 3.3 8.0 0.0 2.9 2 1 1 3 3 3 0 Helix-hairpin-helix motif DMP12 PF16779.5 AIN95883.1 - 0.041 13.9 0.0 0.071 13.1 0.0 1.4 1 0 0 1 1 1 0 DNA-mimic protein IMS_HHH PF11798.8 AIN95883.1 - 0.14 12.6 0.0 28 5.3 0.0 2.7 2 0 0 2 2 2 0 IMS family HHH motif DNA_pol_B_palm PF14792.6 AIN95884.1 - 9.3e-26 90.3 0.0 2.1e-25 89.2 0.0 1.6 1 0 0 1 1 1 1 DNA polymerase beta palm DNA_pol_B_thumb PF14791.6 AIN95884.1 - 2.8e-15 56.2 1.2 7.7e-14 51.6 0.5 3.2 2 1 0 2 2 2 1 DNA polymerase beta thumb DNA_pol_lambd_f PF10391.9 AIN95884.1 - 9.1e-08 31.8 0.1 6.3e-07 29.1 0.1 2.3 1 1 0 1 1 1 1 Fingers domain of DNA polymerase lambda HHH_8 PF14716.6 AIN95884.1 - 0.00098 19.4 0.4 2.1 8.8 0.0 4.0 4 0 0 4 4 4 1 Helix-hairpin-helix domain HHH_5 PF14520.6 AIN95884.1 - 0.0047 17.5 0.9 0.031 14.9 0.0 2.9 3 0 0 3 3 3 1 Helix-hairpin-helix domain NTP_transf_2 PF01909.23 AIN95884.1 - 0.029 14.7 0.0 0.064 13.6 0.0 1.5 1 0 0 1 1 1 0 Nucleotidyltransferase domain COPR5 PF15340.6 AIN95884.1 - 3.9 8.1 4.9 2.8 8.6 0.1 2.9 3 0 0 3 3 3 0 Cooperator of PRMT5 family Lactamase_B_4 PF13691.6 AIN95885.1 - 3.2e-05 23.5 0.0 0.0001 21.9 0.0 1.8 1 0 0 1 1 1 1 tRNase Z endonuclease Lactamase_B_2 PF12706.7 AIN95885.1 - 0.0023 17.5 0.3 0.025 14.1 0.1 2.4 2 0 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 AIN95885.1 - 0.47 10.4 3.6 0.23 11.5 0.4 2.2 2 0 0 2 2 2 0 Metallo-beta-lactamase superfamily Pkinase PF00069.25 AIN95887.1 - 6e-60 202.8 0.0 1e-59 202.1 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 AIN95887.1 - 2.9e-42 144.8 0.0 4.3e-42 144.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 AIN95887.1 - 3.6e-05 23.2 0.0 5.3e-05 22.7 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 AIN95887.1 - 0.001 19.1 4.6 0.068 13.1 0.1 2.9 2 1 1 3 3 3 2 Phosphotransferase enzyme family PKS_DE PF18369.1 AIN95887.1 - 5.8 7.6 7.3 0.46 11.1 1.4 2.2 2 0 0 2 2 2 0 Polyketide synthase dimerisation element domain Glyoxalase_3 PF13468.6 AIN95888.1 - 0.037 14.1 0.4 0.077 13.1 0.4 1.4 1 0 0 1 1 1 0 Glyoxalase-like domain Dpy-30 PF05186.13 AIN95890.1 - 1.5e-07 31.0 0.7 4.5e-07 29.4 0.1 2.0 2 0 0 2 2 2 1 Dpy-30 motif DUF2924 PF11149.8 AIN95890.1 - 4.9 7.5 7.9 3.8 7.9 4.3 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF2924) TMEM65 PF10507.9 AIN95891.1 - 1e-29 102.7 1.0 3.8e-29 100.8 0.8 2.2 2 0 0 2 2 2 1 Transmembrane protein 65 EF-hand_1 PF00036.32 AIN95891.1 - 0.24 11.0 0.0 0.42 10.3 0.0 1.4 1 0 0 1 1 1 0 EF hand CaM_binding PF07839.11 AIN95891.1 - 1.1 10.1 5.3 0.49 11.2 1.2 2.2 2 0 0 2 2 2 0 Plant calmodulin-binding domain DnaJ PF00226.31 AIN95893.1 - 5.7e-19 68.0 0.5 5.7e-09 36.0 0.1 2.6 2 0 0 2 2 2 2 DnaJ domain AAA_5 PF07728.14 AIN95894.1 - 7.8e-83 275.4 0.0 4.9e-32 110.8 0.0 3.7 3 0 0 3 3 3 3 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 AIN95894.1 - 2.2e-07 31.4 1.4 0.013 15.9 0.0 4.4 4 0 0 4 4 3 2 AAA ATPase domain AAA_7 PF12775.7 AIN95894.1 - 5.5e-06 26.0 0.2 0.0051 16.3 0.1 2.5 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA PF00004.29 AIN95894.1 - 2e-05 25.0 0.1 0.096 13.1 0.1 3.1 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) TsaE PF02367.17 AIN95894.1 - 2.2e-05 24.5 0.1 0.0088 16.0 0.1 2.5 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_22 PF13401.6 AIN95894.1 - 6.1e-05 23.3 0.9 0.024 14.9 0.1 3.5 3 1 0 3 3 3 1 AAA domain IstB_IS21 PF01695.17 AIN95894.1 - 0.00015 21.6 0.0 0.089 12.5 0.0 3.4 3 0 0 3 3 3 1 IstB-like ATP binding protein AAA_3 PF07726.11 AIN95894.1 - 0.00033 20.5 0.0 0.16 11.8 0.0 2.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.6 AIN95894.1 - 0.0011 18.7 0.0 0.72 9.6 0.0 2.7 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_14 PF13173.6 AIN95894.1 - 0.0024 17.9 0.0 0.69 10.0 0.0 2.5 2 0 0 2 2 2 1 AAA domain VWA PF00092.28 AIN95894.1 - 0.005 17.1 0.0 0.012 15.9 0.0 1.6 1 0 0 1 1 1 1 von Willebrand factor type A domain Sigma54_activat PF00158.26 AIN95894.1 - 0.0057 16.4 0.1 4.9 6.8 0.0 3.4 3 0 0 3 3 3 1 Sigma-54 interaction domain VWA_2 PF13519.6 AIN95894.1 - 0.0059 17.2 0.0 0.022 15.4 0.0 2.1 1 0 0 1 1 1 1 von Willebrand factor type A domain AAA_18 PF13238.6 AIN95894.1 - 0.0079 16.7 0.0 0.53 10.8 0.0 2.7 2 0 0 2 2 2 1 AAA domain TniB PF05621.11 AIN95894.1 - 0.0083 15.6 0.0 2.6 7.4 0.0 2.7 2 0 0 2 2 2 1 Bacterial TniB protein AAA_33 PF13671.6 AIN95894.1 - 0.0097 16.1 0.0 0.45 10.7 0.0 3.4 3 0 0 3 3 2 1 AAA domain Rad17 PF03215.15 AIN95894.1 - 0.014 15.3 0.0 0.068 13.1 0.0 2.1 2 0 0 2 2 2 0 Rad17 P-loop domain Mg_chelatase PF01078.21 AIN95894.1 - 0.014 14.8 1.1 0.76 9.1 0.0 3.3 4 0 0 4 4 4 0 Magnesium chelatase, subunit ChlI AAA_2 PF07724.14 AIN95894.1 - 0.017 15.2 0.0 2.5 8.2 0.0 2.7 2 0 0 2 2 2 0 AAA domain (Cdc48 subfamily) DUF815 PF05673.13 AIN95894.1 - 0.023 13.9 0.0 2.4 7.3 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) ABC_tran PF00005.27 AIN95894.1 - 0.063 13.8 0.0 1.4 9.4 0.0 2.9 2 0 0 2 2 2 0 ABC transporter RuvB_N PF05496.12 AIN95894.1 - 0.069 12.9 0.0 2.7 7.7 0.0 2.6 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain SMC_N PF02463.19 AIN95894.1 - 0.085 12.3 0.0 1.4 8.3 0.0 2.2 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 AIN95894.1 - 0.098 12.6 0.0 6.7 6.6 0.0 2.5 2 0 0 2 2 2 0 RsgA GTPase RNA_helicase PF00910.22 AIN95894.1 - 0.16 12.4 0.0 1.4 9.4 0.0 2.3 2 0 0 2 2 2 0 RNA helicase DUF615 PF04751.14 AIN95894.1 - 0.4 10.7 4.9 0.093 12.7 0.8 2.0 2 0 0 2 2 1 0 Protein of unknown function (DUF615) ZapB PF06005.12 AIN95894.1 - 6.7 7.2 6.4 19 5.8 2.5 3.0 2 0 0 2 2 2 0 Cell division protein ZapB Peptidase_C1 PF00112.23 AIN95895.1 - 3.3e-69 233.3 2.1 5.4e-69 232.6 2.1 1.3 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.12 AIN95895.1 - 1.6e-10 41.2 2.1 2.8e-10 40.5 2.1 1.4 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) DUF3586 PF12131.8 AIN95895.1 - 2e-10 40.8 0.3 5.1e-10 39.4 0.3 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3586) Peptidase_C1_2 PF03051.15 AIN95895.1 - 9.3e-05 21.4 0.3 0.011 14.5 0.1 2.2 2 0 0 2 2 2 2 Peptidase C1-like family Hist_deacetyl PF00850.19 AIN95896.1 - 1.5e-57 195.4 0.0 2.5e-57 194.7 0.0 1.4 1 1 0 1 1 1 1 Histone deacetylase domain RHH_5 PF07878.11 AIN95896.1 - 0.015 15.1 0.1 0.04 13.8 0.1 1.8 1 0 0 1 1 1 0 CopG-like RHH_1 or ribbon-helix-helix domain, RHH_5 zf-RING_2 PF13639.6 AIN95897.1 - 2e-08 34.4 6.5 2e-08 34.4 6.5 4.1 4 0 0 4 4 4 2 Ring finger domain zf-C3HC4_2 PF13923.6 AIN95897.1 - 0.00066 19.5 5.5 0.00066 19.5 5.5 5.0 4 1 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 AIN95897.1 - 0.00081 19.1 7.6 0.00081 19.1 7.6 3.2 3 0 0 3 3 3 1 RING-like zinc finger zf-C3HC4 PF00097.25 AIN95897.1 - 0.0054 16.6 6.4 0.0054 16.6 6.4 4.6 4 1 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-HC5HC2H PF13771.6 AIN95897.1 - 0.0092 16.2 2.3 0.0092 16.2 2.3 4.2 2 1 2 4 4 4 2 PHD-like zinc-binding domain zf-RING_5 PF14634.6 AIN95897.1 - 0.013 15.4 5.5 0.013 15.4 5.5 4.1 4 1 0 4 4 4 0 zinc-RING finger domain zf-HC5HC2H_2 PF13832.6 AIN95897.1 - 0.018 15.2 3.6 0.018 15.2 3.6 4.5 2 1 2 4 4 4 0 PHD-zinc-finger like domain zf-C3HC4_3 PF13920.6 AIN95897.1 - 0.018 14.9 6.6 0.018 14.9 6.6 4.9 4 1 0 4 4 4 0 Zinc finger, C3HC4 type (RING finger) DUF4684 PF15736.5 AIN95898.1 - 0.017 13.8 2.1 0.025 13.3 2.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4684) TPR_1 PF00515.28 AIN95899.1 - 3e-51 169.2 34.4 1.3e-07 31.1 0.0 9.5 9 0 0 9 9 9 9 Tetratricopeptide repeat TPR_2 PF07719.17 AIN95899.1 - 5.9e-43 141.5 31.3 4.4e-05 23.3 0.0 9.6 9 0 0 9 9 9 9 Tetratricopeptide repeat STI1 PF17830.1 AIN95899.1 - 4.9e-29 100.0 5.5 7.3e-15 54.6 1.4 3.5 3 0 0 3 3 3 2 STI1 domain TPR_11 PF13414.6 AIN95899.1 - 5.2e-28 96.5 26.9 7.8e-07 28.7 0.3 8.5 6 1 2 8 8 8 7 TPR repeat TPR_8 PF13181.6 AIN95899.1 - 1.1e-21 75.2 25.4 0.00062 19.8 0.0 9.0 9 0 0 9 9 8 6 Tetratricopeptide repeat TPR_12 PF13424.6 AIN95899.1 - 1.4e-19 70.2 20.9 5.4e-07 29.8 0.3 7.4 5 2 2 7 7 7 5 Tetratricopeptide repeat TPR_19 PF14559.6 AIN95899.1 - 1.5e-17 63.9 6.0 0.083 13.4 0.2 6.7 5 1 1 6 6 6 5 Tetratricopeptide repeat TPR_14 PF13428.6 AIN95899.1 - 4.5e-16 58.2 9.6 0.18 12.7 0.0 9.3 5 3 5 10 10 9 2 Tetratricopeptide repeat TPR_16 PF13432.6 AIN95899.1 - 7.4e-16 58.5 9.0 0.00031 21.3 0.1 6.7 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_17 PF13431.6 AIN95899.1 - 6e-11 41.9 15.6 0.25 11.8 0.3 8.1 8 0 0 8 8 7 4 Tetratricopeptide repeat TPR_9 PF13371.6 AIN95899.1 - 8.2e-10 38.7 1.3 0.00028 21.0 0.0 4.8 5 2 1 7 7 4 2 Tetratricopeptide repeat TPR_7 PF13176.6 AIN95899.1 - 1.8e-09 37.0 12.9 0.33 11.1 0.0 8.6 8 1 1 9 9 8 2 Tetratricopeptide repeat TPR_10 PF13374.6 AIN95899.1 - 2.2e-08 33.7 18.9 0.015 15.1 0.0 8.8 10 0 0 10 10 9 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 AIN95899.1 - 2.3e-07 30.8 3.0 1.1 9.4 0.0 6.1 7 0 0 7 7 7 2 Fis1 C-terminal tetratricopeptide repeat ANAPC3 PF12895.7 AIN95899.1 - 0.0001 22.4 24.8 0.091 13.0 4.5 6.2 4 2 2 6 6 6 4 Anaphase-promoting complex, cyclosome, subunit 3 MIT PF04212.18 AIN95899.1 - 0.00098 19.1 23.7 0.32 11.1 0.2 7.8 7 1 1 8 8 8 2 MIT (microtubule interacting and transport) domain TPR_20 PF14561.6 AIN95899.1 - 0.00098 19.4 2.6 1.9 8.9 0.0 4.4 4 1 0 4 4 4 1 Tetratricopeptide repeat SHNi-TPR PF10516.9 AIN95899.1 - 0.0027 17.1 8.8 1.1 8.8 0.0 5.4 7 0 0 7 7 5 1 SHNi-TPR TPR_6 PF13174.6 AIN95899.1 - 0.0039 17.7 25.0 2.7 8.8 0.1 8.9 9 0 0 9 9 9 1 Tetratricopeptide repeat DUF3856 PF12968.7 AIN95899.1 - 0.02 15.0 9.6 5.6 7.0 0.2 5.4 3 3 1 5 5 5 0 Domain of Unknown Function (DUF3856) TPR_3 PF07720.12 AIN95899.1 - 0.056 13.5 23.2 0.099 12.7 0.5 6.1 6 0 0 6 6 6 0 Tetratricopeptide repeat FAM165 PF14981.6 AIN95899.1 - 0.068 13.0 0.3 0.27 11.1 0.3 2.1 1 0 0 1 1 1 0 FAM165 family BTAD PF03704.17 AIN95899.1 - 0.077 13.4 7.2 1.4 9.3 0.5 4.7 3 2 1 5 5 5 0 Bacterial transcriptional activator domain TPM_phosphatase PF04536.14 AIN95899.1 - 0.092 12.9 1.5 3.2 7.9 0.1 3.6 3 0 0 3 3 3 0 TPM domain DnaI_N PF07319.11 AIN95899.1 - 0.15 12.7 3.0 4.5 8.0 0.0 4.0 4 1 0 5 5 3 0 Primosomal protein DnaI N-terminus DUF5113 PF17140.4 AIN95899.1 - 0.34 10.7 9.3 47 3.8 0.0 5.2 3 2 3 6 6 6 0 Domain of unknown function (DUF5113) RPN7 PF10602.9 AIN95899.1 - 7.4 6.2 10.1 0.69 9.6 0.9 3.3 1 1 2 3 3 3 0 26S proteasome subunit RPN7 DUF1126 PF06565.12 AIN95900.1 - 3.2e-60 200.5 0.0 4e-25 87.7 0.0 3.3 3 0 0 3 3 3 3 DUF1126 PH-like domain EF-hand_1 PF00036.32 AIN95900.1 - 0.005 16.3 0.0 0.025 14.1 0.0 2.2 2 0 0 2 2 2 1 EF hand EF-hand_5 PF13202.6 AIN95900.1 - 0.0099 15.3 0.0 0.027 14.0 0.0 1.7 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.6 AIN95900.1 - 0.061 13.3 0.0 0.72 9.9 0.0 2.8 3 0 0 3 3 3 0 EF-hand domain Pribosyltran_N PF13793.6 AIN95901.1 - 3.2e-35 120.6 0.1 6.7e-35 119.5 0.1 1.6 1 0 0 1 1 1 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.6 AIN95901.1 - 1.2e-22 80.8 0.6 5.1e-22 78.8 0.3 2.0 1 1 1 2 2 2 1 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.27 AIN95901.1 - 1e-18 67.3 0.4 1.9e-18 66.5 0.4 1.4 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.6 AIN95901.1 - 0.005 16.3 0.1 0.0088 15.5 0.1 1.4 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Sec3_C PF09763.9 AIN95903.1 - 3.4e-78 263.8 0.0 1.1e-77 262.1 0.0 1.7 1 1 0 1 1 1 1 Exocyst complex component Sec3 DUF812 PF05667.11 AIN95903.1 - 0.00028 19.9 1.6 0.00045 19.2 1.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF812) Vps54_N PF10475.9 AIN95903.1 - 0.015 14.6 5.7 0.029 13.7 5.7 1.4 1 0 0 1 1 1 0 Vacuolar-sorting protein 54, of GARP complex POX PF07526.11 AIN95903.1 - 0.037 14.6 0.8 2.3 8.8 0.8 2.9 2 0 0 2 2 2 0 Associated with HOX VP4_helical PF17478.2 AIN95903.1 - 0.12 11.8 0.2 0.67 9.3 0.0 2.1 2 0 0 2 2 2 0 Rotavirus VP4 helical domain THOC7 PF05615.13 AIN95903.1 - 0.13 12.6 8.4 0.49 10.7 8.4 2.0 1 0 0 1 1 1 0 Tho complex subunit 7 Mce4_CUP1 PF11887.8 AIN95903.1 - 0.25 10.7 1.6 0.48 9.8 1.6 1.4 1 0 0 1 1 1 0 Cholesterol uptake porter CUP1 of Mce4, putative YabA PF06156.13 AIN95903.1 - 0.45 11.2 2.4 1.4 9.5 2.4 1.9 1 0 0 1 1 1 0 Initiation control protein YabA Exonuc_VII_L PF02601.15 AIN95903.1 - 0.81 9.2 6.7 2.2 7.8 6.7 1.7 1 0 0 1 1 1 0 Exonuclease VII, large subunit TPMT PF05724.11 AIN95904.1 - 5.2e-17 62.2 0.0 1.1e-16 61.2 0.0 1.4 1 0 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) Methyltransf_23 PF13489.6 AIN95904.1 - 0.00038 20.3 0.0 0.00059 19.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 AIN95904.1 - 0.0079 16.9 0.0 0.015 15.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain mTERF PF02536.14 AIN95905.1 - 4.6e-06 25.8 0.0 0.00014 20.9 0.0 2.0 1 1 1 2 2 2 2 mTERF FAST_1 PF06743.15 AIN95905.1 - 0.021 14.7 0.1 8.8 6.4 0.0 3.5 2 1 1 3 3 3 0 FAST kinase-like protein, subdomain 1 Slu7 PF11708.8 AIN95906.1 - 0.00052 19.9 7.2 0.00052 19.9 7.2 2.7 3 1 1 4 4 4 1 Pre-mRNA splicing Prp18-interacting factor BTK PF00779.19 AIN95906.1 - 0.011 15.6 3.4 0.022 14.6 3.4 1.5 1 0 0 1 1 1 0 BTK motif zf-CCHC_5 PF14787.6 AIN95906.1 - 0.063 13.0 1.8 0.12 12.1 1.8 1.4 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger tRNA-synt_1c PF00749.21 AIN95906.1 - 0.11 11.4 0.2 0.18 10.6 0.2 1.3 1 0 0 1 1 1 0 tRNA synthetases class I (E and Q), catalytic domain zf-CCHC PF00098.23 AIN95906.1 - 0.22 11.6 2.5 0.46 10.7 2.5 1.6 1 0 0 1 1 1 0 Zinc knuckle ANAPC4_WD40 PF12894.7 AIN95907.1 - 2.5e-12 46.9 1.6 7.1e-06 26.2 0.0 5.8 3 2 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Coatomer_WDAD PF04053.14 AIN95907.1 - 2.2e-10 40.2 2.6 0.0025 17.0 0.1 4.5 4 0 0 4 4 4 2 Coatomer WD associated region TPR_7 PF13176.6 AIN95907.1 - 0.00022 21.0 6.3 0.067 13.3 0.3 4.4 4 0 0 4 4 4 2 Tetratricopeptide repeat WD40 PF00400.32 AIN95907.1 - 0.0044 17.8 11.9 0.75 10.8 0.0 6.4 7 0 0 7 7 6 1 WD domain, G-beta repeat eIF2A PF08662.11 AIN95907.1 - 0.0073 16.2 0.1 0.18 11.7 0.0 2.6 2 1 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A Clathrin PF00637.20 AIN95907.1 - 0.016 15.1 8.3 1.1 9.1 0.2 4.4 3 1 2 5 5 5 0 Region in Clathrin and VPS zf-RanBP PF00641.18 AIN95907.1 - 0.034 13.5 12.3 0.038 13.3 4.2 2.7 2 0 0 2 2 2 0 Zn-finger in Ran binding protein and others Vps39_1 PF10366.9 AIN95907.1 - 0.077 13.3 0.3 0.26 11.6 0.3 1.9 1 0 0 1 1 1 0 Vacuolar sorting protein 39 domain 1 RPN7 PF10602.9 AIN95907.1 - 0.44 10.2 2.8 3.7 7.2 0.2 3.1 1 1 2 3 3 3 0 26S proteasome subunit RPN7 TPR_12 PF13424.6 AIN95907.1 - 0.83 10.0 18.3 0.42 10.9 0.5 4.5 5 1 0 5 5 4 0 Tetratricopeptide repeat TPR_14 PF13428.6 AIN95907.1 - 1.4 10.0 14.2 0.26 12.2 0.9 4.4 5 0 0 5 5 3 0 Tetratricopeptide repeat TPR_6 PF13174.6 AIN95907.1 - 2.1 9.1 3.8 11 6.9 0.2 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.17 AIN95907.1 - 3.2 8.1 18.8 0.7 10.2 1.2 5.0 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_16 PF13432.6 AIN95907.1 - 4.3 8.1 10.7 26 5.6 0.1 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat MIX PF18529.1 AIN95908.1 - 1.6e-94 313.6 1.0 1.8e-94 313.4 1.0 1.0 1 0 0 1 1 1 1 Mitochondrial membrane-anchored proteins zf-C3HC4 PF00097.25 AIN95910.1 - 1.7e-09 37.4 7.6 3.3e-09 36.4 7.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 AIN95910.1 - 3.6e-09 36.5 3.9 3.6e-09 36.5 3.9 2.5 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 AIN95910.1 - 1.8e-08 34.1 10.0 2.5e-08 33.6 1.8 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 AIN95910.1 - 7.1e-08 32.5 5.9 1.9e-07 31.1 5.9 1.8 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 AIN95910.1 - 2.6e-07 30.5 7.3 7e-07 29.1 7.3 1.7 1 1 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 AIN95910.1 - 8.7e-07 28.7 7.2 1.6e-06 27.8 7.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 AIN95910.1 - 3.1e-06 27.4 8.2 6e-06 26.5 8.2 1.5 1 0 0 1 1 1 1 Ring finger domain Prok-RING_4 PF14447.6 AIN95910.1 - 0.0006 19.6 6.2 0.0013 18.6 6.2 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-rbx1 PF12678.7 AIN95910.1 - 0.0066 16.7 5.5 0.018 15.3 5.5 1.7 1 1 0 1 1 1 1 RING-H2 zinc finger domain Croc_4 PF17691.1 AIN95910.1 - 0.066 13.3 1.0 0.18 11.8 1.0 1.7 1 0 0 1 1 1 0 Contingent replication of cDNA 4 zf-ANAPC11 PF12861.7 AIN95910.1 - 0.12 12.4 2.4 0.26 11.3 2.4 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-Nse PF11789.8 AIN95910.1 - 1.1 9.1 6.0 2.6 7.9 6.0 1.6 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-RING_11 PF17123.5 AIN95910.1 - 1.3 8.9 5.3 3.4 7.5 5.3 1.8 1 1 0 1 1 1 0 RING-like zinc finger DUF885 PF05960.11 AIN95911.1 - 0.0036 17.0 1.4 0.006 16.3 1.4 1.2 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF885) TolA_bind_tri PF16331.5 AIN95911.1 - 0.01 15.9 0.2 0.027 14.5 0.2 1.6 1 0 0 1 1 1 0 TolA binding protein trimerisation PKcGMP_CC PF16808.5 AIN95911.1 - 0.039 13.8 0.3 0.11 12.4 0.3 1.7 1 0 0 1 1 1 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Kinesin_assoc PF16183.5 AIN95911.1 - 0.15 12.2 0.4 0.38 10.9 0.4 1.5 1 1 0 1 1 1 0 Kinesin-associated DUF4407 PF14362.6 AIN95911.1 - 0.68 9.2 3.3 0.97 8.7 2.8 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Pkinase PF00069.25 AIN95916.1 - 8.7e-48 163.0 0.0 5e-47 160.5 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 AIN95916.1 - 4.1e-34 118.0 0.0 6.7e-34 117.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 AIN95916.1 - 2.9e-05 23.5 0.0 5e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 AIN95916.1 - 0.0023 16.8 0.0 0.0037 16.1 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase RIO1 PF01163.22 AIN95916.1 - 0.011 15.3 0.0 0.024 14.3 0.0 1.5 1 0 0 1 1 1 0 RIO1 family APH PF01636.23 AIN95916.1 - 0.032 14.2 0.0 0.093 12.6 0.0 1.8 1 0 0 1 1 1 0 Phosphotransferase enzyme family CLZ PF16526.5 AIN95917.1 - 0.0078 16.5 1.9 0.0078 16.5 1.9 1.6 2 0 0 2 2 2 1 C-terminal leucine zipper domain of cyclic nucleotide-gated channels SlyX PF04102.12 AIN95917.1 - 0.02 15.5 3.1 1.1 9.9 0.4 2.3 2 0 0 2 2 2 0 SlyX DUF1192 PF06698.11 AIN95917.1 - 0.02 14.9 0.6 0.02 14.9 0.6 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF1192) EspB_PE PF18625.1 AIN95917.1 - 0.023 15.2 1.1 0.037 14.5 0.2 1.8 2 0 0 2 2 2 0 ESX-1 secreted protein B PE domain DHR10 PF18595.1 AIN95917.1 - 0.038 14.1 5.4 0.038 14.1 5.4 1.9 2 0 0 2 2 2 0 Designed helical repeat protein 10 domain DUF4407 PF14362.6 AIN95917.1 - 0.065 12.6 2.1 0.08 12.3 2.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF3138 PF11336.8 AIN95917.1 - 0.084 11.5 0.2 0.1 11.2 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) PIN_2 PF10130.9 AIN95917.1 - 0.1 12.9 0.9 0.17 12.1 0.4 1.6 1 1 1 2 2 2 0 PIN domain FlaC_arch PF05377.11 AIN95917.1 - 0.14 12.6 4.9 0.27 11.7 4.0 1.9 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) AAA_assoc_C PF09821.9 AIN95917.1 - 0.21 12.1 2.8 4.1 8.0 0.1 2.1 2 0 0 2 2 2 0 C-terminal AAA-associated domain DivIC PF04977.15 AIN95917.1 - 0.41 10.5 4.8 8.1 6.3 1.3 2.3 2 0 0 2 2 2 0 Septum formation initiator NuA4 PF09340.10 AIN95917.1 - 0.48 10.3 2.3 0.9 9.5 2.3 1.5 1 0 0 1 1 1 0 Histone acetyltransferase subunit NuA4 LMBR1 PF04791.16 AIN95917.1 - 0.89 8.4 2.5 0.95 8.3 2.5 1.0 1 0 0 1 1 1 0 LMBR1-like membrane protein ANAPC4_WD40 PF12894.7 AIN95918.1 - 0.00015 22.0 0.0 1.3 9.4 0.0 3.5 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Frtz PF11768.8 AIN95918.1 - 0.04 12.3 0.0 0.24 9.7 0.0 2.0 2 1 1 3 3 3 0 WD repeat-containing and planar cell polarity effector protein Fritz DUF2415 PF10313.9 AIN95918.1 - 0.088 12.8 0.1 0.34 10.9 0.0 2.0 2 0 0 2 2 2 0 Uncharacterised protein domain (DUF2415) WD40_like PF17005.5 AIN95918.1 - 0.11 11.7 0.0 23 4.2 0.0 2.9 2 1 0 2 2 2 0 WD40-like domain WD40 PF00400.32 AIN95918.1 - 0.99 10.4 6.1 1.7e+02 3.3 0.5 4.9 5 1 0 5 5 5 0 WD domain, G-beta repeat PEX11 PF05648.14 AIN95921.1 - 2.9e-10 40.0 1.0 2e-05 24.2 0.1 2.4 2 1 0 2 2 2 2 Peroxisomal biogenesis factor 11 (PEX11) PIG-L PF02585.17 AIN95922.1 - 5.2e-22 78.9 0.0 7.4e-22 78.4 0.0 1.2 1 0 0 1 1 1 1 GlcNAc-PI de-N-acetylase HhH-GPD PF00730.25 AIN95923.1 - 1.7e-19 70.2 0.0 2.7e-19 69.6 0.0 1.3 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.23 AIN95923.1 - 1.8e-07 30.6 0.0 4.8e-07 29.3 0.0 1.8 1 0 0 1 1 1 1 Helix-hairpin-helix motif EndIII_4Fe-2S PF10576.9 AIN95923.1 - 0.013 15.8 3.4 0.023 15.0 3.4 1.5 1 0 0 1 1 1 0 Iron-sulfur binding domain of endonuclease III Toxin_R_bind_C PF07951.12 AIN95923.1 - 0.08 12.6 0.0 0.11 12.1 0.0 1.2 1 0 0 1 1 1 0 Clostridium neurotoxin, C-terminal receptor binding RRM_1 PF00076.22 AIN95924.1 - 2.7e-18 65.6 0.0 3.3e-18 65.2 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 AIN95924.1 - 0.00036 20.6 0.0 0.0012 18.9 0.0 2.0 1 1 1 2 2 2 1 RNA recognition motif RNA_bind PF08675.11 AIN95924.1 - 0.014 15.4 0.0 0.034 14.2 0.0 1.6 1 0 0 1 1 1 0 RNA binding domain HA2 PF04408.23 AIN95925.1 - 1.9e-18 66.8 0.1 6.8e-18 64.9 0.1 2.0 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 AIN95925.1 - 2.5e-13 50.2 0.0 5.3e-13 49.1 0.0 1.5 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 AIN95925.1 - 1.2e-11 44.9 0.0 3.3e-11 43.5 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 AIN95925.1 - 6.7e-11 42.3 0.1 1.8e-10 40.8 0.1 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase RWD PF05773.22 AIN95925.1 - 3.4e-05 24.1 0.0 0.00011 22.4 0.0 1.9 2 0 0 2 2 2 1 RWD domain zf-CCHC PF00098.23 AIN95925.1 - 6.1e-05 22.9 5.4 6.8e-05 22.8 0.9 2.6 2 0 0 2 2 2 1 Zinc knuckle T2SSE PF00437.20 AIN95925.1 - 0.00014 21.0 0.0 0.00031 19.9 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_19 PF13245.6 AIN95925.1 - 0.00021 21.6 0.2 0.0007 19.9 0.1 1.9 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 AIN95925.1 - 0.002 18.4 0.9 0.017 15.4 0.4 2.9 2 1 0 2 2 2 1 AAA domain AAA_30 PF13604.6 AIN95925.1 - 0.01 15.6 0.0 0.027 14.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 AIN95925.1 - 0.051 14.1 0.2 0.2 12.1 0.0 2.1 2 0 0 2 2 2 0 AAA domain ATPase PF06745.13 AIN95925.1 - 0.063 12.6 0.0 0.15 11.4 0.0 1.6 1 0 0 1 1 1 0 KaiC LPD22 PF18834.1 AIN95925.1 - 0.064 13.5 0.1 21 5.4 0.1 2.5 2 0 0 2 2 2 0 Large polyvalent protein associated domain 22 RRM_1 PF00076.22 AIN95926.1 - 7.6e-18 64.1 0.0 1.4e-17 63.3 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 AIN95926.1 - 0.0095 16.0 0.0 0.024 14.8 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif RRM_5 PF13893.6 AIN95926.1 - 0.026 14.1 0.0 0.048 13.2 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.22 AIN95927.1 - 4e-16 58.6 0.0 6.4e-16 57.9 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 AIN95927.1 - 0.18 12.0 0.0 0.47 10.6 0.0 1.6 1 1 0 1 1 1 0 RNA recognition motif BILBO1_N PF18281.1 AIN95928.1 - 2.4e-31 108.0 0.1 8e-31 106.3 0.1 2.0 1 0 0 1 1 1 1 BILBO1 N-terminal domain EF-hand_7 PF13499.6 AIN95928.1 - 1.3e-10 41.6 3.0 1.3e-10 41.6 3.0 2.9 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.32 AIN95928.1 - 6.2e-07 28.5 3.1 0.016 14.7 0.0 3.1 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.6 AIN95928.1 - 1.3e-05 24.7 2.1 0.15 12.1 0.3 3.3 3 0 0 3 3 3 2 EF-hand domain EF-hand_8 PF13833.6 AIN95928.1 - 0.00087 19.1 1.8 0.016 15.0 0.7 2.5 1 1 1 2 2 2 2 EF-hand domain pair Tropomyosin_1 PF12718.7 AIN95928.1 - 0.015 15.5 4.7 0.015 15.5 4.7 3.3 2 1 1 3 3 3 0 Tropomyosin like EF-hand_5 PF13202.6 AIN95928.1 - 0.095 12.2 0.0 0.31 10.6 0.0 1.9 1 0 0 1 1 1 0 EF hand DUF3584 PF12128.8 AIN95928.1 - 0.097 10.2 62.9 0.027 12.0 33.7 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) MscS_porin PF12795.7 AIN95928.1 - 2.1 7.9 47.4 0.21 11.1 11.3 2.8 1 1 0 2 2 2 0 Mechanosensitive ion channel porin domain Phycobilisome PF00502.19 AIN95929.1 - 0.0055 16.7 0.5 0.0072 16.3 0.5 1.2 1 0 0 1 1 1 1 Phycobilisome protein HTH_Tnp_ISL3 PF13542.6 AIN95929.1 - 0.19 11.2 2.2 0.33 10.4 1.3 2.0 1 1 1 2 2 2 0 Helix-turn-helix domain of transposase family ISL3 Kinesin PF00225.23 AIN95931.1 - 7.1e-75 252.0 9.0 2.2e-45 155.0 0.0 3.8 4 2 0 4 4 4 2 Kinesin motor domain Microtub_bd PF16796.5 AIN95931.1 - 4.5e-16 59.1 0.0 1.4e-15 57.5 0.0 1.9 1 0 0 1 1 1 1 Microtubule binding AAA_22 PF13401.6 AIN95931.1 - 0.0095 16.2 0.1 0.0095 16.2 0.1 3.0 3 1 0 3 3 3 1 AAA domain Fez1 PF06818.15 AIN95931.1 - 0.47 10.9 47.9 0.02 15.4 12.0 4.5 2 1 1 4 4 4 0 Fez1 DUF87 PF01935.17 AIN95931.1 - 1.7 8.6 0.0 1.7 8.6 0.0 3.3 3 1 0 3 3 3 0 Helicase HerA, central domain zf-CRD PF17979.1 AIN95932.1 - 5.1e-44 150.2 0.5 5.1e-44 150.2 0.5 2.6 2 1 0 2 2 1 1 Cysteine rich domain with multizinc binding regions FHA PF00498.26 AIN95932.1 - 2.4e-15 56.6 0.0 8.7e-15 54.8 0.0 2.0 1 0 0 1 1 1 1 FHA domain FHA_2 PF17913.1 AIN95932.1 - 2e-06 28.0 0.0 3.4e-06 27.2 0.0 1.4 1 0 0 1 1 1 1 FHA domain zf-C3HC4 PF00097.25 AIN95932.1 - 2.3e-06 27.3 12.5 2.3e-06 27.3 12.5 3.4 4 1 0 4 4 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 AIN95932.1 - 0.0003 20.6 13.7 0.0003 20.6 13.7 4.2 5 0 0 5 5 5 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 AIN95932.1 - 0.0003 20.9 13.1 0.0003 20.9 13.1 3.6 5 0 0 5 5 4 1 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.6 AIN95932.1 - 0.00039 20.7 15.3 0.00039 20.7 15.3 4.0 5 1 0 5 5 3 1 Ring finger domain zf-RING_6 PF14835.6 AIN95932.1 - 0.00048 19.9 5.6 0.00048 19.9 5.6 2.9 2 1 1 3 3 1 1 zf-RING of BARD1-type protein zf-RING_UBOX PF13445.6 AIN95932.1 - 0.00056 19.9 14.3 0.00056 19.9 14.3 3.1 4 0 0 4 4 2 1 RING-type zinc-finger Yop-YscD_cpl PF16697.5 AIN95932.1 - 0.0012 19.1 0.3 0.0053 17.0 0.1 2.2 3 0 0 3 3 2 1 Inner membrane component of T3SS, cytoplasmic domain zf-RING_5 PF14634.6 AIN95932.1 - 0.0013 18.7 13.6 0.0013 18.7 13.6 4.0 3 1 0 3 3 2 1 zinc-RING finger domain zf-CCHH PF10283.9 AIN95932.1 - 0.0015 18.5 10.2 0.0015 18.5 10.2 2.0 2 0 0 2 2 2 1 PBZ domain zf-Nse PF11789.8 AIN95932.1 - 0.5 10.2 10.0 0.38 10.6 7.1 2.4 2 0 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit Atg8 PF02991.16 AIN95933.1 - 1.5e-06 28.3 0.0 2.3e-06 27.7 0.0 1.3 1 1 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like zf-Paramyx-P PF13008.7 AIN95934.1 - 0.051 13.0 0.2 0.087 12.3 0.2 1.3 1 0 0 1 1 1 0 Zinc-binding domain of Paramyxoviridae V protein TANGO2 PF05742.12 AIN95935.1 - 4.6e-17 62.9 0.0 4e-13 50.0 0.1 3.1 2 1 0 2 2 2 2 Transport and Golgi organisation 2 DUF4586 PF15239.6 AIN95936.1 - 4.3e-34 119.1 5.9 6.7e-34 118.4 5.9 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4586) VTC PF09359.10 AIN95937.1 - 5.9e-78 262.0 0.1 8.5e-78 261.5 0.1 1.2 1 0 0 1 1 1 1 VTC domain DUF202 PF02656.15 AIN95937.1 - 0.002 18.5 0.1 0.002 18.5 0.1 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF202) Phtf-FEM1B_bdg PF12129.8 AIN95937.1 - 0.054 13.3 0.3 0.097 12.5 0.3 1.4 1 0 0 1 1 1 0 Male germ-cell putative homeodomain transcription factor AAA_2 PF07724.14 AIN95938.1 - 5.6e-42 143.8 0.3 8.6e-34 117.1 0.1 2.4 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA PF00004.29 AIN95938.1 - 8.3e-13 48.9 0.4 5.4e-05 23.6 0.1 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 AIN95938.1 - 2.3e-06 27.6 0.1 8.1e-05 22.6 0.0 3.0 3 0 0 3 3 2 1 AAA domain (dynein-related subfamily) ClpB_D2-small PF10431.9 AIN95938.1 - 6.2e-06 26.2 0.3 2.9e-05 24.0 0.0 2.3 2 0 0 2 2 2 1 C-terminal, D2-small domain, of ClpB protein AAA_22 PF13401.6 AIN95938.1 - 9.1e-05 22.8 0.0 0.0041 17.4 0.0 2.6 2 0 0 2 2 2 1 AAA domain MCM PF00493.23 AIN95938.1 - 9.8e-05 21.5 0.2 0.0082 15.3 0.0 2.4 2 0 0 2 2 2 1 MCM P-loop domain AAA_16 PF13191.6 AIN95938.1 - 0.0017 18.7 3.5 0.019 15.4 2.6 2.8 2 1 0 2 2 2 1 AAA ATPase domain ATP-synt_ab PF00006.25 AIN95938.1 - 0.0088 15.7 0.0 0.02 14.6 0.0 1.6 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain Sigma54_activat PF00158.26 AIN95938.1 - 0.009 15.7 0.1 0.16 11.7 0.0 2.8 3 0 0 3 3 2 1 Sigma-54 interaction domain Mg_chelatase PF01078.21 AIN95938.1 - 0.012 15.0 0.5 0.054 12.9 0.0 2.4 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI RuvB_N PF05496.12 AIN95938.1 - 0.014 15.2 0.0 0.54 10.0 0.0 2.4 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain AAA_18 PF13238.6 AIN95938.1 - 0.022 15.3 0.0 0.22 12.1 0.0 2.4 2 1 0 2 2 2 0 AAA domain AAA_19 PF13245.6 AIN95938.1 - 0.029 14.7 0.6 0.099 13.0 0.2 2.1 2 1 0 2 2 2 0 AAA domain AAA_7 PF12775.7 AIN95938.1 - 0.038 13.5 0.0 0.27 10.7 0.0 2.1 2 0 0 2 2 2 0 P-loop containing dynein motor region DEAD PF00270.29 AIN95938.1 - 0.053 13.3 0.1 9.6 5.9 0.0 2.7 3 0 0 3 3 3 0 DEAD/DEAH box helicase AAA_24 PF13479.6 AIN95938.1 - 0.065 12.9 0.1 0.15 11.8 0.0 1.7 2 0 0 2 2 2 0 AAA domain TniB PF05621.11 AIN95938.1 - 0.068 12.6 0.0 0.16 11.3 0.0 1.7 1 0 0 1 1 1 0 Bacterial TniB protein ResIII PF04851.15 AIN95938.1 - 0.11 12.4 0.0 4.5 7.3 0.0 3.0 3 1 0 3 3 3 0 Type III restriction enzyme, res subunit UCH PF00443.29 AIN95939.1 - 8.2e-37 127.1 0.0 1.3e-36 126.4 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 AIN95939.1 - 7.3e-05 22.5 0.1 0.00046 19.9 0.0 2.2 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase MCM PF00493.23 AIN95940.1 - 3.2e-89 297.9 0.0 1.7e-88 295.5 0.0 2.0 1 1 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 AIN95940.1 - 6.3e-35 119.8 0.7 1.1e-34 118.9 0.7 1.4 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 AIN95940.1 - 8.1e-25 87.1 1.9 1.5e-24 86.2 1.9 1.5 1 0 0 1 1 1 1 MCM AAA-lid domain AAA_5 PF07728.14 AIN95940.1 - 4e-09 36.6 0.0 9e-09 35.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) MCM_N PF14551.6 AIN95940.1 - 5.4e-08 33.4 0.0 1.7e-07 31.8 0.0 1.8 2 0 0 2 2 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 AIN95940.1 - 6.3e-08 32.3 0.1 1.2e-05 24.8 0.0 2.7 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.26 AIN95940.1 - 0.0021 17.8 0.2 3.1 7.5 0.0 2.8 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_3 PF07726.11 AIN95940.1 - 0.0022 17.9 0.0 0.0054 16.6 0.0 1.7 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 AIN95940.1 - 0.0035 17.8 0.3 0.052 13.9 0.0 2.7 2 1 1 3 3 3 1 AAA ATPase domain NTPase_1 PF03266.15 AIN95940.1 - 0.06 13.3 0.1 13 5.6 0.0 2.6 1 1 1 2 2 2 0 NTPase Oberon_cc PF16312.5 AIN95940.1 - 0.1 12.5 0.3 0.19 11.7 0.3 1.4 1 0 0 1 1 1 0 Coiled-coil region of Oberon TIP49_C PF17856.1 AIN95940.1 - 0.16 12.1 0.2 0.47 10.6 0.2 1.8 1 0 0 1 1 1 0 TIP49 AAA-lid domain PknG_rubred PF16919.5 AIN95940.1 - 0.17 12.1 0.7 0.81 9.8 0.7 2.2 1 0 0 1 1 1 0 Protein kinase G rubredoxin domain G10 PF01125.17 AIN95941.1 - 2.5e-48 163.6 1.2 1.4e-47 161.1 1.2 1.9 1 1 0 1 1 1 1 G10 protein Xrn1_D3 PF18194.1 AIN95941.1 - 0.087 12.9 0.0 0.3 11.2 0.0 1.8 2 0 0 2 2 2 0 Exoribonuclease 1 Domain-3 MFS_1 PF07690.16 AIN95942.1 - 3e-22 79.0 46.7 1.1e-15 57.5 24.5 2.2 1 1 0 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 AIN95942.1 - 9e-08 31.4 0.6 0.00012 21.1 8.7 1.9 1 1 1 2 2 2 1 MFS_1 like family Kinesin PF00225.23 AIN95944.1 - 7.8e-30 103.9 9.3 2.6e-10 39.7 0.0 3.9 3 1 1 4 4 4 3 Kinesin motor domain HNF-1_N PF04814.13 AIN95945.1 - 0.072 13.7 0.1 1.2 9.7 0.0 2.0 2 0 0 2 2 2 0 Hepatocyte nuclear factor 1 (HNF-1), N terminus Pkinase PF00069.25 AIN95946.1 - 3.9e-48 164.1 0.0 2.2e-47 161.6 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 AIN95946.1 - 1.7e-18 66.9 0.0 1.3e-17 64.0 0.0 2.1 2 1 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 AIN95946.1 - 0.0015 17.9 0.0 0.0025 17.2 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 AIN95946.1 - 0.0058 16.6 0.0 0.0058 16.6 0.0 2.3 2 1 0 2 2 2 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 AIN95946.1 - 0.061 12.3 0.0 0.095 11.6 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Kdo PF06293.14 AIN95946.1 - 0.068 12.5 0.8 0.096 12.0 0.1 1.5 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 AIN95946.1 - 0.08 11.7 0.0 0.12 11.1 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase K1 PF02960.14 AIN95947.1 - 0.053 13.6 0.7 0.13 12.4 0.2 1.8 2 0 0 2 2 2 0 K1 glycoprotein CHASE PF03924.13 AIN95947.1 - 0.2 11.6 2.4 0.8 9.6 0.0 2.7 3 0 0 3 3 3 0 CHASE domain DUF3040 PF11239.8 AIN95948.1 - 0.58 10.5 3.5 9.3 6.6 0.3 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3040) ECD PF18432.1 AIN95949.1 - 0.091 12.7 0.1 0.19 11.7 0.1 1.5 1 0 0 1 1 1 0 Extracellular Cadherin domain EphA2_TM PF14575.6 AIN95949.1 - 0.15 13.0 0.4 29 5.6 0.0 2.7 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain zf-rbx1 PF12678.7 AIN95951.1 - 3.7e-08 33.5 1.7 3.7e-08 33.5 1.7 2.9 3 0 0 3 3 3 1 RING-H2 zinc finger domain zf-RING_2 PF13639.6 AIN95951.1 - 4.1e-08 33.4 7.1 4.1e-08 33.4 7.1 3.7 4 0 0 4 4 4 1 Ring finger domain zf-RING_11 PF17123.5 AIN95951.1 - 6.6e-05 22.6 4.7 0.0003 20.5 1.1 2.6 2 0 0 2 2 2 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 AIN95951.1 - 0.00015 21.5 8.5 0.00015 21.5 8.5 3.0 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 AIN95951.1 - 0.00041 20.2 2.2 0.00041 20.2 2.2 3.0 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 AIN95951.1 - 0.00048 20.1 1.3 0.0016 18.4 1.3 1.9 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.6 AIN95951.1 - 0.0046 16.8 6.2 0.0046 16.8 6.2 3.1 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 AIN95951.1 - 0.0098 15.9 4.2 0.0098 15.9 4.2 2.4 2 0 0 2 2 2 1 RING-type zinc-finger Rad50_zn_hook PF04423.14 AIN95951.1 - 0.9 9.4 3.2 1.7 8.6 0.1 2.2 2 0 0 2 2 2 0 Rad50 zinc hook motif FAD_binding_7 PF03441.14 AIN95952.1 - 5e-34 117.6 0.3 8.1e-34 116.9 0.3 1.3 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.18 AIN95952.1 - 8.5e-18 64.9 0.1 2.9e-17 63.2 0.1 1.9 2 0 0 2 2 2 1 DNA photolyase Ank_4 PF13637.6 AIN95953.1 - 1.9e-07 31.5 0.0 6e-07 29.9 0.0 1.8 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 AIN95953.1 - 3.4e-05 23.9 0.4 0.0054 17.1 0.0 2.8 3 0 0 3 3 3 1 Ankyrin repeat Ank_2 PF12796.7 AIN95953.1 - 0.00028 21.4 0.0 0.0005 20.6 0.0 1.7 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 AIN95953.1 - 0.00066 19.9 0.0 0.0018 18.5 0.0 1.8 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.30 AIN95953.1 - 0.0059 17.0 0.5 0.59 10.7 0.0 3.1 3 0 0 3 3 3 1 Ankyrin repeat CX9C PF16860.5 AIN95954.1 - 2e-05 24.5 1.5 3.3e-05 23.8 1.5 1.3 1 0 0 1 1 1 1 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, CHCH PF06747.13 AIN95954.1 - 0.0041 17.2 1.6 0.41 10.9 0.3 2.2 2 0 0 2 2 2 2 CHCH domain UPF0203 PF05254.12 AIN95954.1 - 0.026 14.8 1.5 0.66 10.3 1.3 2.1 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0203) Cmc1 PF08583.10 AIN95954.1 - 0.045 13.8 1.8 0.35 10.9 1.7 2.0 1 1 0 1 1 1 0 Cytochrome c oxidase biogenesis protein Cmc1 like NDUF_B7 PF05676.13 AIN95954.1 - 0.69 9.7 3.9 4.3 7.1 0.6 2.1 1 1 1 2 2 2 0 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) UPF0242 PF06785.11 AIN95956.1 - 0.072 13.2 8.1 0.16 12.0 8.1 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DUF755 PF05501.11 AIN95956.1 - 0.17 12.2 7.9 0.33 11.2 5.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF755) DUF948 PF06103.11 AIN95956.1 - 0.38 11.1 5.2 0.46 10.8 0.3 2.8 1 1 2 3 3 3 0 Bacterial protein of unknown function (DUF948) HAUS-augmin3 PF14932.6 AIN95956.1 - 1.5 8.4 13.0 3 7.4 13.0 1.4 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 Fib_alpha PF08702.10 AIN95956.1 - 2.6 8.2 8.1 1.8 8.7 2.2 2.6 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family FAM76 PF16046.5 AIN95956.1 - 5.6 6.2 9.6 11 5.3 9.6 1.5 1 0 0 1 1 1 0 FAM76 protein Atg14 PF10186.9 AIN95956.1 - 7.5 5.5 12.0 17 4.4 12.0 1.5 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Pkinase PF00069.25 AIN95958.1 - 2.4e-41 141.9 0.0 3.2e-41 141.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 AIN95958.1 - 2.3e-16 59.9 0.0 3.6e-16 59.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 AIN95958.1 - 0.013 15.5 1.1 2.8 7.8 0.0 2.6 2 1 0 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.14 AIN95958.1 - 0.028 13.8 0.0 0.051 12.9 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-PolyVal PF18762.1 AIN95958.1 - 0.11 12.4 0.0 0.2 11.6 0.0 1.3 1 0 0 1 1 1 0 Serine/Threonine/Tyrosine Kinase found in polyvalent proteins DSPn PF14671.6 AIN95959.1 - 8.2e-19 68.5 0.0 1.4e-12 48.3 0.0 2.3 2 0 0 2 2 2 2 Dual specificity protein phosphatase, N-terminal half DSPc PF00782.20 AIN95959.1 - 2.5e-08 33.8 0.1 4.7e-08 32.9 0.1 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 AIN95959.1 - 0.0013 18.4 0.1 0.0022 17.6 0.1 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase HTH_28 PF13518.6 AIN95959.1 - 0.17 12.1 2.3 0.53 10.4 0.5 2.5 2 0 0 2 2 2 0 Helix-turn-helix domain Plus-3 PF03126.18 AIN95960.1 - 2.6e-13 50.4 0.0 6.6e-13 49.1 0.0 1.7 1 0 0 1 1 1 1 Plus-3 domain zf-C3HC4_3 PF13920.6 AIN95960.1 - 7.6e-10 38.5 14.5 1.2e-09 37.8 14.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 AIN95960.1 - 0.013 15.3 14.3 0.027 14.3 14.3 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 AIN95960.1 - 0.59 10.5 15.8 1.1 9.7 15.8 1.4 1 0 0 1 1 1 0 Ring finger domain TPR_1 PF00515.28 AIN95961.1 - 1.1e-17 63.0 12.6 0.0032 17.2 0.0 9.1 9 0 0 9 9 9 4 Tetratricopeptide repeat TPR_2 PF07719.17 AIN95961.1 - 5e-13 48.1 22.9 0.077 13.1 0.0 8.8 10 0 0 10 10 10 6 Tetratricopeptide repeat TPR_8 PF13181.6 AIN95961.1 - 1.2e-12 46.9 3.9 0.087 13.1 0.0 7.2 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_16 PF13432.6 AIN95961.1 - 1.7e-11 44.6 14.6 0.16 12.6 0.0 7.4 5 1 2 7 7 7 4 Tetratricopeptide repeat TPR_14 PF13428.6 AIN95961.1 - 7.4e-10 38.8 18.4 0.064 14.1 0.9 7.7 5 2 4 9 9 8 4 Tetratricopeptide repeat TPR_12 PF13424.6 AIN95961.1 - 1.5e-09 38.0 13.4 0.21 11.9 0.0 6.8 5 1 1 7 7 7 2 Tetratricopeptide repeat TPR_9 PF13371.6 AIN95961.1 - 2.3e-08 34.0 8.6 0.0036 17.4 0.4 4.5 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_19 PF14559.6 AIN95961.1 - 2.7e-07 31.0 10.4 0.13 12.8 0.1 5.6 4 2 1 5 5 5 3 Tetratricopeptide repeat TPR_17 PF13431.6 AIN95961.1 - 0.00022 21.4 1.8 24 5.6 0.0 6.9 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_11 PF13414.6 AIN95961.1 - 0.00092 18.9 6.8 15 5.4 0.1 6.5 6 2 1 7 7 7 0 TPR repeat Fis1_TPR_C PF14853.6 AIN95961.1 - 0.035 14.2 11.2 0.099 12.7 0.0 4.4 6 0 0 6 6 6 0 Fis1 C-terminal tetratricopeptide repeat TPR_7 PF13176.6 AIN95961.1 - 0.16 12.1 7.9 71 3.8 0.1 6.1 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_6 PF13174.6 AIN95961.1 - 0.24 12.1 11.1 6.8 7.5 0.0 5.0 5 0 0 5 5 4 0 Tetratricopeptide repeat Mon2_C PF16206.5 AIN95963.1 - 1.8e-08 33.0 0.1 4e-08 31.9 0.1 1.5 1 0 0 1 1 1 1 C-terminal region of Mon2 protein Metallophos PF00149.28 AIN95964.1 - 9.7e-22 78.5 0.6 1.4e-21 77.9 0.6 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase IRK_C PF17655.1 AIN95965.1 - 4.7e-08 32.8 0.6 8.8e-05 22.2 0.2 2.3 2 0 0 2 2 2 2 Inward rectifier potassium channel C-terminal domain SPX PF03105.19 AIN95965.1 - 0.1 12.5 9.4 0.13 12.2 9.4 1.2 1 0 0 1 1 1 0 SPX domain Macoilin PF09726.9 AIN95965.1 - 1.3 7.5 11.4 1.8 7.0 11.4 1.1 1 0 0 1 1 1 0 Macoilin family Miga PF10265.9 AIN95965.1 - 9 5.1 7.8 14 4.5 7.8 1.2 1 0 0 1 1 1 0 Mitoguardin Acyltransferase PF01553.21 AIN95966.1 - 0.0015 18.1 0.0 0.0035 17.0 0.0 1.6 1 0 0 1 1 1 1 Acyltransferase bZIP_1 PF00170.21 AIN95970.1 - 0.032 14.3 1.2 0.065 13.3 1.2 1.4 1 0 0 1 1 1 0 bZIP transcription factor LRR_6 PF13516.6 AIN95970.1 - 0.11 12.6 3.7 8.2 6.8 0.0 4.4 4 0 0 4 4 4 0 Leucine Rich repeat ADIP PF11559.8 AIN95970.1 - 0.52 10.4 6.5 0.92 9.6 6.5 1.3 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding LRR_4 PF12799.7 AIN95970.1 - 1 9.9 13.3 9 6.9 0.8 4.9 4 1 1 5 5 5 0 Leucine Rich repeats (2 copies) ZapB PF06005.12 AIN95970.1 - 1.4 9.5 6.3 3.2 8.3 6.3 1.6 1 0 0 1 1 1 0 Cell division protein ZapB EBP50_C PF09007.11 AIN95970.1 - 1.4 9.9 5.9 4 8.5 5.9 1.7 1 0 0 1 1 1 0 EBP50, C-terminal YgaB PF14182.6 AIN95970.1 - 1.4 9.3 4.7 3.4 8.1 4.7 1.6 1 0 0 1 1 1 0 YgaB-like protein DSPc PF00782.20 AIN95972.1 - 7.5e-08 32.3 0.0 1.1e-06 28.5 0.0 2.3 1 1 0 1 1 1 1 Dual specificity phosphatase, catalytic domain 2-oxoacid_dh PF00198.23 AIN95972.1 - 0.16 11.4 0.0 0.27 10.7 0.0 1.3 1 0 0 1 1 1 0 2-oxoacid dehydrogenases acyltransferase (catalytic domain) His_Phos_1 PF00300.22 AIN95973.1 - 1.4e-11 44.4 0.0 4.8e-08 32.9 0.0 2.3 2 0 0 2 2 2 2 Histidine phosphatase superfamily (branch 1) PDEase_II PF02112.15 AIN95973.1 - 0.19 10.8 0.0 0.27 10.3 0.0 1.2 1 0 0 1 1 1 0 cAMP phosphodiesterases class-II LRR_8 PF13855.6 AIN95975.1 - 2.1e-05 24.2 0.1 0.032 14.0 0.1 2.4 1 1 1 2 2 2 2 Leucine rich repeat DUF1582 PF07621.11 AIN95975.1 - 0.00051 19.9 0.7 0.0014 18.5 0.7 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF1582) UvrD-helicase PF00580.21 AIN95976.1 - 5.2e-40 137.9 0.0 8.2e-20 71.6 0.0 2.3 1 1 1 2 2 2 2 UvrD/REP helicase N-terminal domain UvrD_C PF13361.6 AIN95976.1 - 1.6e-27 96.8 0.0 5.8e-14 52.2 0.0 2.4 2 0 0 2 2 2 2 UvrD-like helicase C-terminal domain AAA_19 PF13245.6 AIN95976.1 - 3.5e-25 89.0 0.0 1.2e-24 87.3 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 AIN95976.1 - 4e-09 36.5 2.1 1.7e-05 24.7 0.7 2.5 2 0 0 2 2 2 2 AAA domain UvrD_C_2 PF13538.6 AIN95976.1 - 6.2e-09 35.5 0.0 2e-08 34.0 0.0 1.9 1 1 0 1 1 1 1 UvrD-like helicase C-terminal domain ResIII PF04851.15 AIN95976.1 - 0.042 13.8 0.0 0.1 12.6 0.0 1.6 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit Peptidase_S51 PF03575.17 AIN95977.1 - 2.5e-24 86.1 0.0 3.6e-22 79.0 0.0 2.1 1 1 0 1 1 1 1 Peptidase family S51 PRKCSH-like PF12999.7 AIN95978.1 - 2.9e-08 33.7 0.9 5.7e-07 29.5 0.0 2.3 2 0 0 2 2 2 2 Glucosidase II beta subunit-like PH PF00169.29 AIN95980.1 - 3.7e-12 46.7 0.0 7e-12 45.8 0.0 1.4 1 0 0 1 1 1 1 PH domain PH_13 PF16652.5 AIN95980.1 - 0.00022 21.1 0.0 0.029 14.2 0.0 2.3 1 1 0 1 1 1 1 Pleckstrin homology domain IQ_SEC7_PH PF16453.5 AIN95980.1 - 0.0053 16.7 0.0 0.01 15.8 0.0 1.4 1 0 0 1 1 1 1 PH domain DHHC PF01529.20 AIN95981.1 - 7.7e-25 87.5 15.6 7.7e-25 87.5 15.6 2.6 2 1 0 2 2 2 1 DHHC palmitoyltransferase AAA_33 PF13671.6 AIN95982.1 - 5e-07 30.0 0.1 1.7e-06 28.3 0.1 1.9 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 AIN95982.1 - 1.4e-05 24.5 0.0 3e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin AAA_18 PF13238.6 AIN95982.1 - 2.1e-05 25.1 0.0 6.7e-05 23.5 0.0 1.8 1 1 0 1 1 1 1 AAA domain APS_kinase PF01583.20 AIN95982.1 - 0.00026 20.9 0.2 0.00077 19.4 0.1 1.8 1 1 1 2 2 2 1 Adenylylsulphate kinase AAA_16 PF13191.6 AIN95982.1 - 0.00066 20.1 0.1 0.0022 18.4 0.1 1.9 1 0 0 1 1 1 1 AAA ATPase domain AAA_28 PF13521.6 AIN95982.1 - 0.0031 17.8 0.0 0.013 15.8 0.0 1.9 2 0 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 AIN95982.1 - 0.0039 17.1 0.0 0.0086 16.0 0.0 1.5 1 0 0 1 1 1 1 RsgA GTPase ABC_tran PF00005.27 AIN95982.1 - 0.018 15.6 0.0 0.037 14.5 0.0 1.5 1 0 0 1 1 1 0 ABC transporter Cytidylate_kin PF02224.18 AIN95982.1 - 0.027 14.2 0.0 0.051 13.3 0.0 1.4 1 0 0 1 1 1 0 Cytidylate kinase AAA_22 PF13401.6 AIN95982.1 - 0.044 14.1 0.0 0.15 12.4 0.0 1.9 1 0 0 1 1 1 0 AAA domain CPT PF07931.12 AIN95982.1 - 0.088 12.6 0.0 0.19 11.5 0.1 1.6 1 1 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein PRK PF00485.18 AIN95982.1 - 0.11 12.3 0.0 0.2 11.4 0.0 1.4 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family AAA_17 PF13207.6 AIN95982.1 - 0.12 12.8 0.0 0.49 10.8 0.0 2.0 2 0 0 2 2 2 0 AAA domain Sigma54_activat PF00158.26 AIN95982.1 - 0.13 12.0 0.0 6.7 6.4 0.0 2.4 2 0 0 2 2 2 0 Sigma-54 interaction domain UL41A PF17591.2 AIN95982.1 - 0.13 12.4 0.1 0.4 10.8 0.1 1.8 1 0 0 1 1 1 0 Herpesvirus UL41A dNK PF01712.19 AIN95982.1 - 0.13 12.1 0.0 0.28 11.0 0.0 1.5 1 0 0 1 1 1 0 Deoxynucleoside kinase AAA_29 PF13555.6 AIN95982.1 - 0.16 11.8 0.1 1.5 8.6 0.0 2.5 3 0 0 3 3 3 0 P-loop containing region of AAA domain RNA_helicase PF00910.22 AIN95982.1 - 0.18 12.2 0.0 0.5 10.8 0.0 1.7 1 0 0 1 1 1 0 RNA helicase DUF2075 PF09848.9 AIN95982.1 - 0.21 10.8 0.0 0.31 10.2 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) TYW3 PF02676.14 AIN95983.1 - 9.5e-57 191.8 0.0 1.4e-56 191.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase TYW3 Prefoldin_2 PF01920.20 AIN95984.1 - 7e-19 67.7 2.0 9e-19 67.4 2.0 1.1 1 0 0 1 1 1 1 Prefoldin subunit DASH_Dad3 PF08656.10 AIN95984.1 - 0.019 15.0 3.4 0.028 14.5 0.8 2.0 2 0 0 2 2 2 0 DASH complex subunit Dad3 SlyX PF04102.12 AIN95984.1 - 0.025 15.2 3.8 0.16 12.6 0.1 2.3 2 0 0 2 2 2 0 SlyX GreA_GreB_N PF03449.15 AIN95984.1 - 0.075 13.2 0.6 0.075 13.2 0.6 2.0 2 0 0 2 2 2 0 Transcription elongation factor, N-terminal Hemerythrin PF01814.23 AIN95984.1 - 0.12 13.0 1.9 0.71 10.5 2.3 1.8 1 1 1 2 2 2 0 Hemerythrin HHE cation binding domain RB_B PF01857.20 AIN95984.1 - 0.15 12.1 1.1 0.68 10.0 1.1 1.9 1 1 0 1 1 1 0 Retinoblastoma-associated protein B domain Spc24 PF08286.11 AIN95984.1 - 0.26 11.5 4.5 3.5 7.9 0.4 2.1 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 APG6_N PF17675.1 AIN95984.1 - 0.28 11.7 6.6 5.1 7.6 1.6 2.1 2 0 0 2 2 2 0 Apg6 coiled-coil region FapA PF03961.13 AIN95984.1 - 2.5 6.6 5.1 2.6 6.6 0.9 2.0 1 1 0 2 2 2 0 Flagellar Assembly Protein A Nic96 PF04097.14 AIN95985.1 - 0.12 10.8 0.3 0.15 10.5 0.3 1.1 1 0 0 1 1 1 0 Nup93/Nic96 RNA12 PF10443.9 AIN95987.1 - 0.019 13.7 0.1 0.074 11.8 0.0 1.8 2 0 0 2 2 2 0 RNA12 protein zf_CCCH_4 PF18345.1 AIN95988.1 - 2.6e-18 65.4 28.9 5.6e-07 29.4 1.6 6.1 5 1 0 5 5 5 5 Zinc finger domain zf-CCCH PF00642.24 AIN95988.1 - 1.2e-17 63.4 30.3 0.00057 19.7 0.6 5.5 5 0 0 5 5 5 5 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 AIN95988.1 - 1.9e-11 43.5 26.7 4.6e-07 29.5 0.6 5.0 5 0 0 5 5 5 4 CCCH-type zinc finger Torus PF16131.5 AIN95988.1 - 2.1e-11 44.5 21.0 0.00072 20.2 0.4 5.2 1 1 4 5 5 5 5 Torus domain zf-CCCH_3 PF15663.5 AIN95988.1 - 2e-07 31.2 6.9 2e-07 31.2 6.9 2.6 1 1 1 2 2 2 1 Zinc-finger containing family zf-CCHC PF00098.23 AIN95988.1 - 0.00013 21.9 11.4 0.00036 20.5 0.5 3.3 3 0 0 3 3 3 2 Zinc knuckle zf-CCHC_2 PF13696.6 AIN95988.1 - 0.0002 21.1 4.4 0.0016 18.2 0.4 3.0 2 0 0 2 2 2 1 Zinc knuckle zf-CCCH_2 PF14608.6 AIN95988.1 - 0.0005 20.4 1.1 0.0005 20.4 1.1 6.6 7 0 0 7 7 7 3 RNA-binding, Nab2-type zinc finger zf-C3H1 PF10650.9 AIN95988.1 - 3 7.6 8.9 0.84 9.4 0.1 3.9 3 0 0 3 3 3 0 Putative zinc-finger domain zf-UBR PF02207.20 AIN95990.1 - 5e-15 55.4 16.5 5e-15 55.4 16.5 2.8 2 0 0 2 2 2 1 Putative zinc finger in N-recognin (UBR box) ACBP PF00887.19 AIN95991.1 - 1.6e-23 82.7 1.3 3.3e-23 81.7 1.3 1.5 1 0 0 1 1 1 1 Acyl CoA binding protein Mis12 PF05859.12 AIN95991.1 - 0.098 12.7 0.0 0.29 11.2 0.0 1.8 1 0 0 1 1 1 0 Mis12 protein DUF4486 PF14858.6 AIN95992.1 - 0.045 12.2 0.1 0.1 11.1 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4486) HA PF03457.14 AIN95992.1 - 0.34 11.3 1.3 1.3 9.4 0.1 2.7 3 0 0 3 3 3 0 Helicase associated domain Peptidase_S9_N PF02897.15 AIN95993.1 - 9.7e-111 370.5 0.1 1.3e-110 370.1 0.1 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase, N-terminal beta-propeller domain Peptidase_S9 PF00326.21 AIN95993.1 - 3.6e-65 219.4 0.0 5.5e-65 218.8 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Esterase PF00756.20 AIN95993.1 - 0.045 13.4 0.0 0.28 10.8 0.0 2.0 1 1 0 1 1 1 0 Putative esterase DUF4464 PF14713.6 AIN95994.1 - 1.1e-85 286.7 0.1 1.3e-85 286.6 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4464) GAS PF13851.6 AIN95995.1 - 0.22 10.9 1.3 0.37 10.1 1.3 1.3 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding PAP_PilO PF06864.12 AIN95995.1 - 0.28 10.0 3.6 0.11 11.3 0.5 1.9 2 0 0 2 2 2 0 Pilin accessory protein (PilO) DHHC PF01529.20 AIN95995.1 - 4 7.6 12.3 1.8 8.7 0.9 3.6 3 0 0 3 3 3 0 DHHC palmitoyltransferase Prefoldin PF02996.17 AIN95997.1 - 2.1e-10 40.5 0.0 1.2e-09 38.1 0.0 1.9 2 0 0 2 2 2 1 Prefoldin subunit AAA PF00004.29 AIN95998.1 - 0.0021 18.5 0.0 0.0055 17.1 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Zeta_toxin PF06414.12 AIN95998.1 - 0.014 14.7 0.0 0.042 13.1 0.0 1.8 2 0 0 2 2 2 0 Zeta toxin AAA_16 PF13191.6 AIN95998.1 - 0.12 12.7 4.1 0.37 11.1 0.1 3.4 3 1 0 3 3 3 0 AAA ATPase domain Torsin PF06309.11 AIN95998.1 - 0.14 12.3 0.0 3.2 7.9 0.0 2.3 2 0 0 2 2 2 0 Torsin DEAD PF00270.29 AIN95999.1 - 4.4e-27 95.0 0.1 7.3e-27 94.3 0.1 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 AIN95999.1 - 1.2e-20 73.9 0.0 5.4e-20 71.8 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 AIN95999.1 - 0.00011 22.3 0.0 0.00019 21.5 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 AIN95999.1 - 0.022 15.1 0.1 0.064 13.6 0.0 1.8 2 0 0 2 2 2 0 AAA domain SecA_DEAD PF07517.14 AIN95999.1 - 0.15 11.3 0.0 0.4 9.9 0.0 1.6 2 0 0 2 2 2 0 SecA DEAD-like domain UPF0160 PF03690.13 AIN96000.1 - 3.3e-122 408.1 0.0 3.8e-122 407.9 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0160) Ras PF00071.22 AIN96001.1 - 4.9e-37 127.0 0.1 1.3e-11 44.3 0.1 3.1 3 0 0 3 3 3 3 Ras family Roc PF08477.13 AIN96001.1 - 1.2e-20 73.9 0.5 4.5e-09 36.6 0.0 3.0 2 1 1 3 3 3 2 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 AIN96001.1 - 5.1e-05 22.8 0.0 0.39 10.1 0.0 2.9 3 0 0 3 3 3 2 ADP-ribosylation factor family MMR_HSR1 PF01926.23 AIN96001.1 - 0.074 13.1 0.0 0.14 12.3 0.0 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase PET117 PF15786.5 AIN96002.1 - 8.3e-06 26.0 0.0 9.6e-06 25.8 0.0 1.2 1 0 0 1 1 1 1 PET assembly of cytochrome c oxidase, mitochondrial NCKAP5 PF15246.6 AIN96003.1 - 0.038 13.6 6.9 0.056 13.0 6.9 1.2 1 0 0 1 1 1 0 Nck-associated protein 5, Peripheral clock protein Menin PF05053.13 AIN96003.1 - 0.28 9.5 7.2 0.39 9.0 7.2 1.1 1 0 0 1 1 1 0 Menin Bravo_FIGEY PF13882.6 AIN96003.1 - 1 10.7 5.6 3.2 9.2 5.6 1.7 1 0 0 1 1 1 0 Bravo-like intracellular region GvpL_GvpF PF06386.11 AIN96003.1 - 1.5 8.7 12.8 4.2 7.2 12.8 1.7 1 0 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF PhoLip_ATPase_C PF16212.5 AIN96005.1 - 7.6e-53 179.8 20.2 7.6e-53 179.8 20.2 2.3 2 0 0 2 2 2 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 AIN96005.1 - 3e-21 74.9 0.3 6.8e-21 73.7 0.3 1.6 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Hydrolase PF00702.26 AIN96005.1 - 4.1e-08 33.8 0.2 0.013 15.8 0.0 3.5 3 0 0 3 3 3 2 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 AIN96005.1 - 0.00087 18.8 0.0 0.0038 16.8 0.0 2.1 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase PF13246.6 AIN96005.1 - 0.015 15.4 0.0 0.76 9.9 0.0 3.3 4 0 0 4 4 4 0 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 AIN96005.1 - 0.015 15.0 0.1 0.027 14.2 0.1 1.3 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase EF-hand_7 PF13499.6 AIN96006.1 - 8.9e-07 29.3 1.1 1.2e-05 25.6 0.1 2.3 2 1 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.6 AIN96006.1 - 4.2e-06 26.3 1.3 1.9e-05 24.2 0.0 2.8 4 0 0 4 4 4 1 EF-hand domain EF-hand_1 PF00036.32 AIN96006.1 - 4.4e-06 25.8 3.8 2.6e-05 23.4 0.0 3.0 3 0 0 3 3 3 1 EF hand EF-hand_8 PF13833.6 AIN96006.1 - 0.00015 21.5 1.3 0.14 12.0 0.5 2.7 2 0 0 2 2 2 2 EF-hand domain pair DUF1456 PF07308.13 AIN96006.1 - 0.034 14.5 0.5 1 9.8 0.0 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1456) EFhand_Ca_insen PF08726.10 AIN96006.1 - 0.042 13.9 0.4 2.7 8.2 0.2 2.6 2 2 0 2 2 2 0 Ca2+ insensitive EF hand YokU PF14122.6 AIN96006.1 - 0.64 10.0 4.2 2.1 8.4 0.4 2.7 1 1 2 3 3 3 0 YokU-like protein, putative antitoxin EF-hand_5 PF13202.6 AIN96006.1 - 9.6 5.9 6.5 7.3 6.3 0.0 3.5 4 0 0 4 4 4 0 EF hand EF-hand_1 PF00036.32 AIN96007.1 - 3e-43 142.2 12.0 1.5e-10 39.9 1.0 4.1 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 AIN96007.1 - 1.6e-36 124.6 3.7 6.9e-19 68.1 1.2 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 AIN96007.1 - 5e-32 109.5 11.3 1.3e-14 53.7 0.7 4.1 1 1 3 4 4 4 4 EF-hand domain pair EF-hand_6 PF13405.6 AIN96007.1 - 2.1e-31 105.1 6.6 1.3e-09 37.2 0.1 4.4 4 1 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 AIN96007.1 - 3.2e-28 95.9 9.4 5.8e-07 28.7 0.0 4.2 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.6 AIN96007.1 - 6.6e-16 58.4 0.2 6.8e-09 35.9 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.7 AIN96007.1 - 1.3e-09 37.9 0.8 5.4e-05 23.1 0.1 2.3 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 AIN96007.1 - 6.6e-08 32.9 0.0 0.0014 18.9 0.0 2.1 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_11 PF08976.11 AIN96007.1 - 2.6e-06 28.2 0.0 0.00063 20.6 0.0 2.1 1 1 1 2 2 2 1 EF-hand domain UPF0154 PF03672.13 AIN96007.1 - 1.9e-05 24.6 1.0 0.035 14.1 0.0 3.3 3 1 1 4 4 4 2 Uncharacterised protein family (UPF0154) EFhand_Ca_insen PF08726.10 AIN96007.1 - 0.00016 21.7 1.1 0.00074 19.6 0.1 2.3 2 2 0 2 2 2 1 Ca2+ insensitive EF hand Dockerin_1 PF00404.18 AIN96007.1 - 0.00017 21.7 2.8 0.017 15.3 0.4 3.1 1 1 2 3 3 3 1 Dockerin type I domain TerB PF05099.13 AIN96007.1 - 0.00041 20.3 0.3 0.23 11.4 0.0 2.3 1 1 1 2 2 2 2 Tellurite resistance protein TerB DUF3349 PF11829.8 AIN96007.1 - 0.00091 20.0 0.3 3.2 8.6 0.0 2.9 1 1 2 3 3 3 1 Protein of unknown function (DUF3349) Caleosin PF05042.13 AIN96007.1 - 0.0013 18.6 0.8 0.21 11.5 0.3 3.3 1 1 1 2 2 2 1 Caleosin related protein RNA_pol_Rpb4 PF03874.16 AIN96007.1 - 0.0018 18.6 0.3 1.6 9.1 0.1 2.5 2 0 0 2 2 2 1 RNA polymerase Rpb4 DUF4497 PF14924.6 AIN96007.1 - 0.0024 18.3 0.0 0.92 10.0 0.0 2.1 1 1 1 2 2 2 1 Protein of unknown function (DUF4497) Poly_export PF02563.16 AIN96007.1 - 0.0042 17.3 0.2 0.9 9.8 0.0 3.1 1 1 0 2 2 2 1 Polysaccharide biosynthesis/export protein MotA_activ PF09114.10 AIN96007.1 - 0.0059 16.7 0.0 0.12 12.5 0.0 2.2 2 0 0 2 2 2 1 Transcription factor MotA, activation domain DUF1103 PF06513.11 AIN96007.1 - 0.0061 16.2 1.1 0.0071 16.0 1.1 1.1 1 0 0 1 1 1 1 Repeat of unknown function (DUF1103) SurA_N_2 PF13623.6 AIN96007.1 - 0.015 15.2 1.4 0.56 10.1 0.2 2.2 1 1 1 2 2 2 0 SurA N-terminal domain DUF5580 PF17743.1 AIN96007.1 - 0.019 13.6 0.0 0.019 13.5 0.0 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5580) EF-hand_14 PF17959.1 AIN96007.1 - 0.033 14.5 0.2 5.6 7.4 0.0 2.4 1 1 1 2 2 2 0 EF-hand domain dCache_2 PF08269.11 AIN96007.1 - 0.04 13.1 0.1 2.7 7.1 0.0 2.2 1 1 0 2 2 2 0 Cache domain Fe_hyd_lg_C PF02906.14 AIN96007.1 - 0.045 13.4 0.2 0.11 12.1 0.2 1.7 1 1 0 1 1 1 0 Iron only hydrogenase large subunit, C-terminal domain RloB PF13707.6 AIN96007.1 - 0.081 13.1 0.9 1.1 9.4 0.1 2.1 1 1 1 2 2 2 0 RloB-like protein EF-hand_1 PF00036.32 AIN96008.1 - 3e-43 142.2 12.0 1.5e-10 39.9 1.0 4.1 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 AIN96008.1 - 1.6e-36 124.6 3.7 6.9e-19 68.1 1.2 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 AIN96008.1 - 5e-32 109.5 11.3 1.3e-14 53.7 0.7 4.1 1 1 3 4 4 4 4 EF-hand domain pair EF-hand_6 PF13405.6 AIN96008.1 - 2.1e-31 105.1 6.6 1.3e-09 37.2 0.1 4.4 4 1 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 AIN96008.1 - 3.2e-28 95.9 9.4 5.8e-07 28.7 0.0 4.2 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.6 AIN96008.1 - 6.6e-16 58.4 0.2 6.8e-09 35.9 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.7 AIN96008.1 - 1.3e-09 37.9 0.8 5.4e-05 23.1 0.1 2.3 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 AIN96008.1 - 6.6e-08 32.9 0.0 0.0014 18.9 0.0 2.1 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_11 PF08976.11 AIN96008.1 - 2.6e-06 28.2 0.0 0.00063 20.6 0.0 2.1 1 1 1 2 2 2 1 EF-hand domain UPF0154 PF03672.13 AIN96008.1 - 1.9e-05 24.6 1.0 0.035 14.1 0.0 3.3 3 1 1 4 4 4 2 Uncharacterised protein family (UPF0154) EFhand_Ca_insen PF08726.10 AIN96008.1 - 0.00016 21.7 1.1 0.00074 19.6 0.1 2.3 2 2 0 2 2 2 1 Ca2+ insensitive EF hand Dockerin_1 PF00404.18 AIN96008.1 - 0.00017 21.7 2.8 0.017 15.3 0.4 3.1 1 1 2 3 3 3 1 Dockerin type I domain TerB PF05099.13 AIN96008.1 - 0.00041 20.3 0.3 0.23 11.4 0.0 2.3 1 1 1 2 2 2 2 Tellurite resistance protein TerB DUF3349 PF11829.8 AIN96008.1 - 0.00091 20.0 0.3 3.2 8.6 0.0 2.9 1 1 2 3 3 3 1 Protein of unknown function (DUF3349) Caleosin PF05042.13 AIN96008.1 - 0.0013 18.6 0.8 0.21 11.5 0.3 3.3 1 1 1 2 2 2 1 Caleosin related protein RNA_pol_Rpb4 PF03874.16 AIN96008.1 - 0.0018 18.6 0.3 1.6 9.1 0.1 2.5 2 0 0 2 2 2 1 RNA polymerase Rpb4 DUF4497 PF14924.6 AIN96008.1 - 0.0024 18.3 0.0 0.92 10.0 0.0 2.1 1 1 1 2 2 2 1 Protein of unknown function (DUF4497) Poly_export PF02563.16 AIN96008.1 - 0.0042 17.3 0.2 0.9 9.8 0.0 3.1 1 1 0 2 2 2 1 Polysaccharide biosynthesis/export protein MotA_activ PF09114.10 AIN96008.1 - 0.0059 16.7 0.0 0.12 12.5 0.0 2.2 2 0 0 2 2 2 1 Transcription factor MotA, activation domain DUF1103 PF06513.11 AIN96008.1 - 0.0061 16.2 1.1 0.0071 16.0 1.1 1.1 1 0 0 1 1 1 1 Repeat of unknown function (DUF1103) SurA_N_2 PF13623.6 AIN96008.1 - 0.015 15.2 1.4 0.56 10.1 0.2 2.2 1 1 1 2 2 2 0 SurA N-terminal domain DUF5580 PF17743.1 AIN96008.1 - 0.019 13.6 0.0 0.019 13.5 0.0 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5580) EF-hand_14 PF17959.1 AIN96008.1 - 0.033 14.5 0.2 5.6 7.4 0.0 2.4 1 1 1 2 2 2 0 EF-hand domain dCache_2 PF08269.11 AIN96008.1 - 0.04 13.1 0.1 2.7 7.1 0.0 2.2 1 1 0 2 2 2 0 Cache domain Fe_hyd_lg_C PF02906.14 AIN96008.1 - 0.045 13.4 0.2 0.11 12.1 0.2 1.7 1 1 0 1 1 1 0 Iron only hydrogenase large subunit, C-terminal domain RloB PF13707.6 AIN96008.1 - 0.081 13.1 0.9 1.1 9.4 0.1 2.1 1 1 1 2 2 2 0 RloB-like protein FbpA PF05833.11 AIN96009.1 - 5e-30 104.7 0.3 1.7e-21 76.5 0.0 2.3 2 0 0 2 2 2 2 Fibronectin-binding protein A N-terminus (FbpA) NFACT-R_1 PF05670.13 AIN96009.1 - 1e-22 80.9 0.0 2.6e-22 79.5 0.0 1.8 1 0 0 1 1 1 1 NFACT protein RNA binding domain NFACT-C PF11923.8 AIN96009.1 - 2.4e-07 30.6 0.0 1.4e-06 28.2 0.0 2.4 1 0 0 1 1 1 1 NFACT protein C-terminal domain SepSecS PF05889.13 AIN96010.1 - 2.1e-91 306.5 0.0 2.2e-50 171.5 0.0 3.4 3 1 0 3 3 3 3 O-phosphoseryl-tRNA(Sec) selenium transferase, SepSecS Beta_elim_lyase PF01212.21 AIN96010.1 - 0.00021 20.7 0.0 0.00032 20.1 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase DUF2550 PF10739.9 AIN96011.1 - 0.049 13.6 0.2 0.14 12.2 0.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2550) Reo_sigma1 PF01664.16 AIN96011.1 - 0.14 11.4 0.1 0.44 9.8 0.1 1.7 1 0 0 1 1 1 0 Reovirus viral attachment protein sigma 1 SUIM_assoc PF16619.5 AIN96011.1 - 0.54 10.4 7.4 18 5.5 4.2 2.5 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 EF1G PF00647.19 AIN96012.1 - 4.7e-40 135.9 0.1 1.4e-39 134.4 0.1 1.8 1 0 0 1 1 1 1 Elongation factor 1 gamma, conserved domain GST_N PF02798.20 AIN96012.1 - 2.5e-12 46.9 0.1 9e-12 45.2 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 AIN96012.1 - 2.6e-12 46.8 0.0 2.6e-12 46.8 0.0 2.3 3 0 0 3 3 3 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 AIN96012.1 - 2e-06 27.9 1.4 5.1e-06 26.6 0.0 2.3 2 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 AIN96012.1 - 5e-05 23.3 0.0 0.00013 21.9 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 AIN96012.1 - 0.0012 19.2 0.0 0.0035 17.7 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_5 PF18485.1 AIN96012.1 - 0.17 12.3 0.0 0.51 10.7 0.0 1.8 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain PAM2 PF07145.15 AIN96013.1 - 0.00086 18.8 3.1 0.012 15.2 0.0 3.3 3 0 0 3 3 3 1 Ataxin-2 C-terminal region Chorein_N PF12624.7 AIN96014.1 - 2.7e-22 79.1 0.1 7.6e-22 77.6 0.0 1.8 2 0 0 2 2 2 1 N-terminal region of Chorein or VPS13 VPS13 PF16908.5 AIN96014.1 - 2e-14 54.0 0.0 4.2e-14 52.9 0.0 1.5 1 0 0 1 1 1 1 Vacuolar sorting-associated protein 13, N-terminal PUB PF09409.10 AIN96015.1 - 1.5e-11 44.0 0.0 3.4e-11 42.9 0.0 1.6 1 0 0 1 1 1 1 PUB domain zf-CHCC PF10276.9 AIN96015.1 - 0.0016 18.4 0.4 0.005 16.9 0.4 1.9 1 0 0 1 1 1 1 Zinc-finger domain OB_RNB PF08206.11 AIN96015.1 - 0.047 13.4 0.1 0.093 12.4 0.1 1.4 1 0 0 1 1 1 0 Ribonuclease B OB domain DUF2256 PF10013.9 AIN96015.1 - 0.12 12.5 1.7 0.25 11.5 0.1 2.2 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2256) zf-C3HC4_3 PF13920.6 AIN96016.1 - 2.3e-10 40.1 12.8 2.3e-10 40.1 12.8 2.2 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) UEV PF05743.13 AIN96016.1 - 6.6e-10 38.9 0.0 1.5e-09 37.8 0.0 1.6 1 0 0 1 1 1 1 UEV domain Prok-RING_4 PF14447.6 AIN96016.1 - 0.00037 20.3 11.1 0.00037 20.3 11.1 2.1 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 UQ_con PF00179.26 AIN96016.1 - 0.037 13.7 0.1 0.087 12.5 0.1 1.5 1 1 0 1 1 1 0 Ubiquitin-conjugating enzyme Big_3_3 PF13750.6 AIN96017.1 - 0.098 12.3 0.0 0.94 9.1 0.0 2.3 2 0 0 2 2 2 0 Bacterial Ig-like domain (group 3) CDC50 PF03381.15 AIN96018.1 - 3.8e-64 216.9 0.0 6.8e-64 216.1 0.0 1.4 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family RNF111_N PF15303.6 AIN96018.1 - 0.023 14.5 6.9 0.036 13.8 6.9 1.2 1 0 0 1 1 1 0 E3 ubiquitin-protein ligase Arkadia N-terminus PTS_EIIB PF00367.20 AIN96019.1 - 0.17 11.4 0.2 0.39 10.3 0.2 1.5 1 0 0 1 1 1 0 phosphotransferase system, EIIB HAP1_N PF04849.13 AIN96019.1 - 0.52 9.5 9.2 1.8 7.7 3.2 2.4 2 1 0 2 2 2 0 HAP1 N-terminal conserved region UPF0242 PF06785.11 AIN96019.1 - 0.75 9.9 5.9 1.2 9.3 1.1 2.2 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus PRKG1_interact PF15898.5 AIN96019.1 - 2.3 9.1 13.8 0.33 11.9 6.0 2.4 2 1 0 2 2 2 0 cGMP-dependent protein kinase interacting domain Takusan PF04822.13 AIN96019.1 - 2.7 8.0 8.5 0.4 10.6 1.2 3.1 2 1 0 3 3 3 0 Takusan APG6_N PF17675.1 AIN96019.1 - 5.3 7.6 11.4 4.2 7.9 7.0 2.3 2 1 0 2 2 2 0 Apg6 coiled-coil region Cep57_CLD_2 PF14197.6 AIN96019.1 - 5.3 7.2 10.9 0.54 10.4 1.7 3.0 3 0 0 3 3 3 0 Centrosome localisation domain of PPC89 LCAT PF02450.15 AIN96020.1 - 2e-45 155.7 0.0 6.6e-35 121.0 0.0 2.2 1 1 1 2 2 2 2 Lecithin:cholesterol acyltransferase Abhydrolase_6 PF12697.7 AIN96020.1 - 0.0058 17.3 0.3 0.0058 17.3 0.3 2.1 2 1 0 2 2 2 1 Alpha/beta hydrolase family Rrp44_CSD1 PF17216.3 AIN96020.1 - 0.0072 16.0 0.0 0.021 14.5 0.0 1.7 2 0 0 2 2 2 1 Rrp44-like cold shock domain Hairy_orange PF07527.13 AIN96020.1 - 0.091 13.0 0.0 0.2 11.9 0.0 1.6 1 0 0 1 1 1 0 Hairy Orange Motile_Sperm PF00635.26 AIN96021.1 - 3.4e-11 42.9 0.0 5.8e-11 42.2 0.0 1.3 1 0 0 1 1 1 1 MSP (Major sperm protein) domain DUF4775 PF16001.5 AIN96021.1 - 2.6 7.4 5.4 3.6 6.9 5.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4775) SHS2_Rpb7-N PF03876.17 AIN96022.1 - 1.4e-24 86.2 0.0 3.1e-24 85.1 0.0 1.6 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 RNA_pol_Rbc25 PF08292.12 AIN96022.1 - 4.2e-09 36.7 0.0 7.6e-08 32.6 0.0 2.4 1 1 0 1 1 1 1 RNA polymerase III subunit Rpc25 DUF4653 PF15546.6 AIN96022.1 - 0.04 13.5 0.3 0.059 13.0 0.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4653) eIF2_C PF09173.11 AIN96023.1 - 3.8e-27 94.4 0.1 8.4e-27 93.3 0.1 1.6 1 0 0 1 1 1 1 Initiation factor eIF2 gamma, C terminal GTP_EFTU_D2 PF03144.25 AIN96023.1 - 2.9e-06 27.6 2.5 1.1e-05 25.7 1.0 2.4 2 0 0 2 2 2 1 Elongation factor Tu domain 2 GTP_EFTU PF00009.27 AIN96024.1 - 1.8e-23 83.1 0.3 4.1e-23 81.9 0.3 1.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain eIF2_C PF09173.11 AIN96024.1 - 3.3e-12 46.5 0.0 1.4e-11 44.5 0.0 2.2 1 1 0 1 1 1 1 Initiation factor eIF2 gamma, C terminal GTP_EFTU_D2 PF03144.25 AIN96024.1 - 0.00016 22.0 2.6 0.0012 19.1 0.9 3.1 3 1 0 3 3 3 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 AIN96024.1 - 0.00078 19.5 0.0 0.0024 17.9 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 AIN96024.1 - 0.0028 17.6 0.2 0.075 12.9 0.1 2.2 2 0 0 2 2 2 1 RsgA GTPase Myosin_tail_1 PF01576.19 AIN96025.1 - 0.0012 16.8 10.5 0.0015 16.5 10.5 1.1 1 0 0 1 1 1 1 Myosin tail DUF4201 PF13870.6 AIN96025.1 - 0.0017 18.1 11.6 0.015 15.1 3.3 2.1 2 0 0 2 2 2 2 Domain of unknown function (DUF4201) Fez1 PF06818.15 AIN96025.1 - 0.005 17.3 4.6 0.005 17.3 4.6 2.0 1 1 1 2 2 2 1 Fez1 Spectrin PF00435.21 AIN96025.1 - 0.0065 16.9 12.8 0.36 11.3 2.4 3.1 2 1 1 3 3 3 1 Spectrin repeat CENP-Q PF13094.6 AIN96025.1 - 0.012 15.8 9.4 0.057 13.6 3.1 2.2 2 0 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit ZapB PF06005.12 AIN96025.1 - 0.049 14.1 12.2 6.4 7.3 2.7 3.6 3 0 0 3 3 3 0 Cell division protein ZapB SpoVAD PF07451.11 AIN96025.1 - 0.062 12.0 0.1 0.086 11.5 0.1 1.1 1 0 0 1 1 1 0 Stage V sporulation protein AD (SpoVAD) DUF4472 PF14739.6 AIN96025.1 - 0.086 13.6 9.0 6.1 7.6 0.0 2.7 1 1 2 3 3 3 0 Domain of unknown function (DUF4472) FUSC PF04632.12 AIN96025.1 - 0.092 11.3 7.6 0.029 12.9 3.2 1.7 1 1 1 2 2 2 0 Fusaric acid resistance protein family Cnn_1N PF07989.11 AIN96025.1 - 0.14 12.3 11.3 0.15 12.3 1.4 3.5 3 1 0 4 4 3 0 Centrosomin N-terminal motif 1 DUF4200 PF13863.6 AIN96025.1 - 0.14 12.5 11.8 0.31 11.5 3.5 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) CCDC154 PF15450.6 AIN96025.1 - 0.15 10.6 12.7 0.22 10.0 12.7 1.2 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 154 Mod_r PF07200.13 AIN96025.1 - 0.2 11.8 13.0 0.23 11.5 11.9 1.7 1 1 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein GIT_CC PF16559.5 AIN96025.1 - 0.44 10.5 7.7 0.49 10.3 1.5 3.4 2 1 2 4 4 4 0 GIT coiled-coil Rho guanine nucleotide exchange factor Cep57_CLD_2 PF14197.6 AIN96025.1 - 0.51 10.5 10.6 0.09 12.9 2.0 3.2 3 0 0 3 3 3 0 Centrosome localisation domain of PPC89 Prominin PF05478.11 AIN96025.1 - 0.51 8.2 7.8 1.7 6.5 7.8 1.6 1 1 0 1 1 1 0 Prominin CENP-H PF05837.12 AIN96025.1 - 0.57 10.6 15.2 0.11 12.9 6.1 2.7 1 1 2 3 3 3 0 Centromere protein H (CENP-H) zf-C4H2 PF10146.9 AIN96025.1 - 0.81 10.0 6.4 2.2 8.5 5.2 1.9 1 1 1 2 2 2 0 Zinc finger-containing protein DUF4407 PF14362.6 AIN96025.1 - 0.95 8.8 15.4 23 4.2 15.5 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) LPP PF04728.13 AIN96025.1 - 1.1 9.7 8.4 5.6 7.4 0.1 3.7 2 1 2 4 4 4 0 Lipoprotein leucine-zipper DUF4570 PF15134.6 AIN96025.1 - 1.5 8.9 8.4 3.7 7.6 0.3 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4570) SlyX PF04102.12 AIN96025.1 - 1.6 9.4 12.9 15 6.3 0.1 3.7 2 1 0 3 3 3 0 SlyX TPR_MLP1_2 PF07926.12 AIN96025.1 - 1.6 8.8 16.5 36 4.4 15.1 3.0 2 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein Spc7 PF08317.11 AIN96025.1 - 1.9 7.3 14.5 2.9 6.7 12.9 1.8 1 1 1 2 2 2 0 Spc7 kinetochore protein V_ATPase_I PF01496.19 AIN96025.1 - 2.1 6.2 5.8 2.6 5.9 5.8 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family LPD5 PF18799.1 AIN96025.1 - 2.1 8.7 8.2 3.6 8.0 5.6 2.4 2 1 0 2 2 2 0 Large polyvalent protein-associated domain 5 Spc24 PF08286.11 AIN96025.1 - 2.9 8.2 15.3 0.43 10.8 3.7 2.8 1 1 2 3 3 3 0 Spc24 subunit of Ndc80 ABC_tran_CTD PF16326.5 AIN96025.1 - 3.4 8.0 14.4 5.2 7.4 4.3 3.4 3 0 0 3 3 3 0 ABC transporter C-terminal domain BRE1 PF08647.11 AIN96025.1 - 3.5 7.8 15.6 0.36 10.9 1.7 2.3 2 1 0 2 2 2 0 BRE1 E3 ubiquitin ligase DUF1664 PF07889.12 AIN96025.1 - 3.9 7.5 9.1 4.9 7.2 0.9 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) DivIC PF04977.15 AIN96025.1 - 5 7.0 14.3 4.8 7.0 1.8 3.5 3 0 0 3 3 3 0 Septum formation initiator Fzo_mitofusin PF04799.13 AIN96025.1 - 6.5 6.3 11.2 3.3 7.2 3.1 2.7 2 1 2 4 4 4 0 fzo-like conserved region DHR10 PF18595.1 AIN96025.1 - 6.5 6.8 19.6 0.46 10.6 4.6 2.8 2 1 1 3 3 3 0 Designed helical repeat protein 10 domain UPF0242 PF06785.11 AIN96025.1 - 7.2 6.7 12.6 24 5.0 12.7 1.8 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Jnk-SapK_ap_N PF09744.9 AIN96025.1 - 7.5 6.8 15.4 2.4 8.4 3.3 2.3 1 1 2 3 3 3 0 JNK_SAPK-associated protein-1 FliD_N PF02465.18 AIN96025.1 - 7.6 7.3 9.0 5.1 7.8 1.7 2.8 2 1 1 3 3 3 0 Flagellar hook-associated protein 2 N-terminus DUF724 PF05266.14 AIN96025.1 - 8.6 6.1 10.9 1.2 8.9 3.7 2.3 1 1 2 3 3 3 0 Protein of unknown function (DUF724) TMPIT PF07851.13 AIN96025.1 - 8.6 5.5 9.6 3.1 7.0 2.9 2.1 1 1 1 2 2 2 0 TMPIT-like protein KELK PF15796.5 AIN96025.1 - 9.2 6.8 13.1 0.95 10.0 1.2 2.7 3 0 0 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase LMBR1 PF04791.16 AIN96025.1 - 10 4.9 6.1 17 4.2 6.1 1.6 1 1 0 1 1 1 0 LMBR1-like membrane protein MRP PF09387.10 AIN96027.1 - 1e-59 201.8 0.2 1.3e-59 201.5 0.2 1.0 1 0 0 1 1 1 1 Mitochondrial RNA binding protein MRP Tim17 PF02466.19 AIN96028.1 - 5.4e-16 58.9 8.9 8.4e-16 58.3 8.9 1.3 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family DUF1069 PF06370.11 AIN96028.1 - 0.028 14.0 0.4 0.044 13.4 0.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1069) Hpt PF01627.23 AIN96028.1 - 0.12 12.6 0.1 0.24 11.7 0.1 1.5 1 0 0 1 1 1 0 Hpt domain DUF3789 PF12664.7 AIN96029.1 - 0.92 9.3 5.2 2 8.2 5.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3789) RRM_1 PF00076.22 AIN96031.1 - 0.16 11.8 0.2 0.47 10.3 0.2 1.7 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Skp1 PF01466.19 AIN96032.1 - 1.3e-07 31.6 0.3 3.3e-07 30.3 0.3 1.8 1 0 0 1 1 1 1 Skp1 family, dimerisation domain DUF4670 PF15709.5 AIN96032.1 - 0.05 12.9 0.1 0.077 12.3 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4670) Ank_4 PF13637.6 AIN96035.1 - 0.013 16.1 0.0 0.057 14.0 0.0 2.2 1 0 0 1 1 1 0 Ankyrin repeats (many copies) Ank_5 PF13857.6 AIN96035.1 - 0.013 15.8 0.2 0.063 13.6 0.0 2.2 2 0 0 2 2 2 0 Ankyrin repeats (many copies) Ank_2 PF12796.7 AIN96035.1 - 0.023 15.3 0.1 0.13 12.9 0.0 2.2 2 0 0 2 2 2 0 Ankyrin repeats (3 copies) Ank_3 PF13606.6 AIN96035.1 - 0.085 13.5 0.2 0.64 10.8 0.0 2.7 2 0 0 2 2 2 0 Ankyrin repeat zf-C3HC4_3 PF13920.6 AIN96036.1 - 8.9e-09 35.1 22.8 8.9e-09 35.1 22.8 2.7 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 AIN96036.1 - 5.4 7.0 30.2 0.1 12.5 22.6 2.1 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 AAA PF00004.29 AIN96037.1 - 6.1e-34 117.3 0.2 1.2e-21 77.5 0.0 3.0 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 AIN96037.1 - 6.2e-08 33.0 1.5 0.00081 19.7 0.0 4.0 3 1 1 4 4 3 1 AAA domain AAA_16 PF13191.6 AIN96037.1 - 1.3e-07 32.2 6.8 3e-05 24.5 0.0 4.5 4 2 1 5 5 4 1 AAA ATPase domain Zot PF05707.12 AIN96037.1 - 3.8e-07 29.9 0.4 0.076 12.7 0.0 4.3 3 2 2 5 5 4 2 Zonular occludens toxin (Zot) AAA_33 PF13671.6 AIN96037.1 - 9.2e-07 29.1 0.0 0.0086 16.2 0.0 3.2 3 0 0 3 3 2 2 AAA domain AAA_14 PF13173.6 AIN96037.1 - 4.8e-06 26.6 0.0 0.00089 19.3 0.0 2.6 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.17 AIN96037.1 - 2e-05 24.4 0.0 0.027 14.2 0.0 2.8 2 0 0 2 2 2 2 IstB-like ATP binding protein TIP49 PF06068.13 AIN96037.1 - 2.1e-05 23.9 0.1 0.014 14.6 0.0 2.5 2 0 0 2 2 2 2 TIP49 P-loop domain AAA_5 PF07728.14 AIN96037.1 - 4.2e-05 23.6 0.0 0.0076 16.3 0.0 3.0 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_7 PF12775.7 AIN96037.1 - 6.2e-05 22.6 0.3 0.0012 18.4 0.1 2.3 2 0 0 2 2 2 1 P-loop containing dynein motor region RNA_helicase PF00910.22 AIN96037.1 - 6.4e-05 23.3 0.0 0.027 14.9 0.0 2.7 2 0 0 2 2 2 1 RNA helicase DUF2075 PF09848.9 AIN96037.1 - 0.00013 21.4 0.1 0.74 9.0 0.0 3.3 2 1 1 3 3 3 2 Uncharacterized conserved protein (DUF2075) Bac_DnaA PF00308.18 AIN96037.1 - 0.00037 20.4 0.1 0.0015 18.4 0.0 1.9 2 0 0 2 2 2 1 Bacterial dnaA protein ABC_tran PF00005.27 AIN96037.1 - 0.00055 20.5 0.2 0.051 14.1 0.0 3.0 3 0 0 3 3 2 1 ABC transporter NACHT PF05729.12 AIN96037.1 - 0.0011 18.9 0.1 0.085 12.8 0.0 3.0 2 0 0 2 2 2 1 NACHT domain RuvB_N PF05496.12 AIN96037.1 - 0.0011 18.7 0.0 0.085 12.6 0.0 2.6 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_18 PF13238.6 AIN96037.1 - 0.0014 19.2 0.0 0.16 12.5 0.0 2.7 2 0 0 2 2 2 1 AAA domain Torsin PF06309.11 AIN96037.1 - 0.0014 18.7 0.2 0.094 12.8 0.1 2.6 2 0 0 2 2 2 1 Torsin Sigma54_activat PF00158.26 AIN96037.1 - 0.0014 18.3 0.1 0.7 9.6 0.1 2.7 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_30 PF13604.6 AIN96037.1 - 0.0027 17.5 0.1 0.24 11.1 0.1 3.0 2 0 0 2 2 2 1 AAA domain Mg_chelatase PF01078.21 AIN96037.1 - 0.0043 16.4 0.2 0.057 12.8 0.1 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI PhoH PF02562.16 AIN96037.1 - 0.011 15.2 1.2 0.21 11.0 0.0 2.9 2 1 1 3 3 3 0 PhoH-like protein RsgA_GTPase PF03193.16 AIN96037.1 - 0.025 14.5 0.0 0.24 11.3 0.0 2.3 2 0 0 2 2 2 0 RsgA GTPase PIF1 PF05970.14 AIN96037.1 - 0.026 13.7 0.5 1.3 8.1 0.1 2.9 3 0 0 3 3 3 0 PIF1-like helicase AAA_2 PF07724.14 AIN96037.1 - 0.028 14.5 0.1 0.22 11.6 0.0 2.5 3 0 0 3 3 3 0 AAA domain (Cdc48 subfamily) APS_kinase PF01583.20 AIN96037.1 - 0.03 14.2 0.1 0.44 10.4 0.1 2.4 2 0 0 2 2 2 0 Adenylylsulphate kinase AAA_29 PF13555.6 AIN96037.1 - 0.033 13.9 1.0 2.9 7.7 0.3 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain Sigma54_activ_2 PF14532.6 AIN96037.1 - 0.051 13.7 0.0 0.96 9.6 0.0 3.0 4 0 0 4 4 2 0 Sigma-54 interaction domain SRP54 PF00448.22 AIN96037.1 - 0.063 12.9 0.2 0.47 10.1 0.0 2.4 3 0 0 3 3 3 0 SRP54-type protein, GTPase domain NB-ARC PF00931.22 AIN96037.1 - 0.069 12.3 0.0 0.21 10.8 0.0 1.8 2 0 0 2 2 1 0 NB-ARC domain AAA_28 PF13521.6 AIN96037.1 - 0.093 13.0 0.0 2.9 8.1 0.0 3.1 3 0 0 3 3 2 0 AAA domain ATPase PF06745.13 AIN96037.1 - 0.1 11.9 0.2 6.4 6.1 0.0 2.5 2 0 0 2 2 2 0 KaiC TsaE PF02367.17 AIN96037.1 - 0.11 12.5 0.3 0.62 10.1 0.2 2.1 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE DAP3 PF10236.9 AIN96037.1 - 0.15 11.2 0.0 0.58 9.3 0.0 1.9 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 Microtub_bd PF16796.5 AIN96037.1 - 0.18 11.7 0.0 0.44 10.5 0.0 1.6 1 0 0 1 1 1 0 Microtubule binding AAA_12 PF13087.6 AIN96039.1 - 1.1e-48 165.5 0.0 2e-48 164.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 AIN96039.1 - 1.6e-33 116.6 8.4 5.7e-19 68.9 0.0 3.3 3 1 0 3 3 3 2 AAA domain AAA_30 PF13604.6 AIN96039.1 - 1.5e-06 28.1 8.6 0.002 17.9 0.1 4.0 4 0 0 4 4 4 2 AAA domain AAA_19 PF13245.6 AIN96039.1 - 2.7e-06 27.8 0.0 1.5e-05 25.3 0.0 2.3 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 AIN96039.1 - 0.0011 19.3 0.0 0.055 13.7 0.0 3.1 2 0 0 2 2 2 1 AAA domain ResIII PF04851.15 AIN96039.1 - 0.0017 18.4 0.0 0.032 14.2 0.0 2.4 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit UvrD-helicase PF00580.21 AIN96039.1 - 0.033 13.7 0.6 0.43 10.1 0.0 2.6 3 0 0 3 3 3 0 UvrD/REP helicase N-terminal domain Helicase_RecD PF05127.14 AIN96039.1 - 0.034 14.0 0.0 5.2 6.9 0.0 3.1 2 0 0 2 2 2 0 Helicase FtsK_SpoIIIE PF01580.18 AIN96039.1 - 0.083 12.2 0.9 4.7 6.5 0.0 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family DUF2075 PF09848.9 AIN96039.1 - 0.11 11.7 0.0 3.8 6.6 0.0 2.4 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) Bromodomain PF00439.25 AIN96041.1 - 2.9e-22 78.5 0.0 1.1e-11 44.6 0.0 2.3 2 0 0 2 2 2 2 Bromodomain MSA-2c PF12238.8 AIN96041.1 - 0.0018 18.3 0.0 0.12 12.4 0.0 2.3 2 0 0 2 2 2 1 Merozoite surface antigen 2c BSD PF03909.17 AIN96041.1 - 0.044 13.8 0.0 7.8 6.6 0.0 2.5 2 0 0 2 2 2 0 BSD domain Mito_carr PF00153.27 AIN96042.1 - 2.2e-44 149.3 6.6 1.4e-17 63.3 0.1 4.2 3 1 0 3 3 3 3 Mitochondrial carrier protein Orthopox_C10L PF07020.11 AIN96042.1 - 2.4 8.9 8.4 1.3 9.8 4.7 2.1 2 0 0 2 2 2 0 Orthopoxvirus C10L protein DZR PF12773.7 AIN96043.1 - 4.5e-05 23.4 1.2 0.012 15.6 0.1 2.4 2 0 0 2 2 2 2 Double zinc ribbon zf-FPG_IleRS PF06827.14 AIN96043.1 - 0.036 13.9 2.1 1.4 8.8 0.1 2.7 2 0 0 2 2 2 0 Zinc finger found in FPG and IleRS HalOD2 PF18547.1 AIN96043.1 - 2.5 8.1 8.7 20 5.1 0.1 4.0 4 0 0 4 4 4 0 Halobacterial output domain 2 Zn_ribbon_SprT PF17283.2 AIN96043.1 - 5.1 7.1 16.4 0.24 11.3 0.8 3.5 3 1 0 3 3 3 0 SprT-like zinc ribbon domain Kelch_4 PF13418.6 AIN96044.1 - 3.3e-05 23.8 0.0 0.88 9.6 0.0 3.3 3 0 0 3 3 3 2 Galactose oxidase, central domain Kelch_5 PF13854.6 AIN96044.1 - 0.00022 21.1 3.0 0.043 13.8 0.3 3.0 2 1 0 2 2 2 2 Kelch motif Kelch_1 PF01344.25 AIN96044.1 - 0.0023 17.5 0.2 2 8.1 0.1 2.7 3 0 0 3 3 3 2 Kelch motif DGOK PF05035.12 AIN96044.1 - 0.049 12.5 1.2 0.063 12.2 1.1 1.3 1 1 0 1 1 1 0 2-keto-3-deoxy-galactonokinase Peptidase_C97 PF05903.14 AIN96045.1 - 7.9e-21 74.5 0.0 1.2e-20 73.9 0.0 1.3 1 1 0 1 1 1 1 PPPDE putative peptidase domain DUF4796 PF16044.5 AIN96045.1 - 0.0023 17.6 0.0 0.0032 17.1 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4796) Flagellar_rod PF05149.12 AIN96047.1 - 5.7e-109 364.0 18.2 5.7e-109 364.0 18.2 1.9 2 0 0 2 2 2 1 Paraflagellar rod protein FTA4 PF13093.6 AIN96047.1 - 0.13 12.1 5.8 0.2 11.5 3.8 2.3 1 1 0 1 1 1 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 Alkyl_sulf_dimr PF14863.6 AIN96047.1 - 7.6 7.0 9.5 53 4.3 5.2 3.4 2 1 0 2 2 2 0 Alkyl sulfatase dimerisation Epiglycanin_C PF14654.6 AIN96048.1 - 0.12 12.4 0.0 0.27 11.3 0.0 1.6 1 0 0 1 1 1 0 Mucin, catalytic, TM and cytoplasmic tail region Histone PF00125.24 AIN96049.1 - 8e-12 45.7 1.3 1e-11 45.3 1.3 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 AIN96049.1 - 0.0002 21.6 0.2 0.00042 20.5 0.2 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone F-box PF00646.33 AIN96053.1 - 0.045 13.6 0.0 0.15 12.0 0.0 1.8 1 0 0 1 1 1 0 F-box domain Glyco_hydro_47 PF01532.20 AIN96054.1 - 1.6e-07 30.7 0.0 2.7e-07 29.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 SET PF00856.28 AIN96055.1 - 1.1e-11 45.4 0.0 2.2e-11 44.5 0.0 1.8 1 1 0 1 1 1 1 SET domain Prominin PF05478.11 AIN96056.1 - 0.098 10.6 0.5 0.1 10.5 0.5 1.1 1 0 0 1 1 1 0 Prominin DUF572 PF04502.13 AIN96056.1 - 0.38 10.3 10.2 0.51 9.9 10.2 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) DUF4570 PF15134.6 AIN96056.1 - 0.44 10.6 7.8 0.023 14.7 2.5 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4570) FAM178 PF14816.6 AIN96056.1 - 0.54 9.2 3.9 0.55 9.1 3.9 1.3 1 0 0 1 1 1 0 Family of unknown function, FAM178 L31 PF09784.9 AIN96056.1 - 0.61 10.5 5.3 0.64 10.5 4.4 1.7 1 1 0 1 1 1 0 Mitochondrial ribosomal protein L31 DUF4407 PF14362.6 AIN96056.1 - 0.9 8.8 6.9 1.2 8.4 6.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF5446 PF17522.2 AIN96056.1 - 1.7 8.9 8.0 0.3 11.3 4.0 1.9 2 0 0 2 2 2 0 Family of unknown function (DUF5446) V_ATPase_I PF01496.19 AIN96056.1 - 2.3 6.0 7.2 2.5 5.9 7.2 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family YtxH PF12732.7 AIN96056.1 - 5.6 7.6 9.6 17 6.1 0.2 2.3 1 1 1 2 2 2 0 YtxH-like protein Coq4 PF05019.13 AIN96057.1 - 8e-49 165.9 0.0 9e-49 165.8 0.0 1.0 1 0 0 1 1 1 1 Coenzyme Q (ubiquinone) biosynthesis protein Coq4 PCSK9_C2 PF18464.1 AIN96057.1 - 0.049 13.7 0.0 0.1 12.6 0.0 1.5 1 0 0 1 1 1 0 Proprotein convertase subtilisin-like/kexin type 9 C-terminal domain DnaJ PF00226.31 AIN96058.1 - 5.6e-12 45.6 0.1 1.1e-11 44.6 0.1 1.5 1 0 0 1 1 1 1 DnaJ domain GcrA PF07750.11 AIN96058.1 - 0.012 16.1 0.0 0.024 15.1 0.0 1.5 1 0 0 1 1 1 0 GcrA cell cycle regulator Rhodanese PF00581.20 AIN96059.1 - 0.00058 20.3 0.0 0.00067 20.2 0.0 1.1 1 0 0 1 1 1 1 Rhodanese-like domain Rhodanese PF00581.20 AIN96060.1 - 6.2e-11 42.8 0.0 8.6e-11 42.3 0.0 1.2 1 0 0 1 1 1 1 Rhodanese-like domain HTH_18 PF12833.7 AIN96060.1 - 0.21 11.9 0.0 0.49 10.7 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain Rhodanese PF00581.20 AIN96061.1 - 8.1e-16 58.5 0.0 9.6e-16 58.2 0.0 1.0 1 0 0 1 1 1 1 Rhodanese-like domain DUF4859 PF16151.5 AIN96061.1 - 0.0019 18.0 0.0 0.0027 17.5 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4859) Mito_carr PF00153.27 AIN96061.1 - 0.097 12.6 0.0 0.15 12.0 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial carrier protein DB_JBP1 PF18526.1 AIN96062.1 - 7.2e-85 283.0 4.9 7.2e-85 283.0 4.9 1.6 2 0 0 2 2 2 1 Thymine dioxygenase JBP1 DNA-binding domain Tet_JBP PF12851.7 AIN96062.1 - 2.2e-20 73.3 0.1 2.7e-16 59.9 0.0 2.5 1 1 1 2 2 2 2 Oxygenase domain of the 2OGFeDO superfamily Cyt-b5 PF00173.28 AIN96063.1 - 1.4e-20 73.2 0.3 1.7e-20 72.9 0.3 1.1 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain CPT PF07931.12 AIN96065.1 - 0.067 13.0 0.1 0.15 11.9 0.1 1.5 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein UPF0180 PF03698.13 AIN96065.1 - 0.15 12.2 0.0 0.41 10.8 0.0 1.7 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0180) LRR_6 PF13516.6 AIN96066.1 - 6e-14 50.8 1.1 0.033 14.2 0.0 6.4 7 0 0 7 7 7 3 Leucine Rich repeat EF-hand_6 PF13405.6 AIN96067.1 - 0.0072 16.2 0.0 0.027 14.4 0.0 2.0 1 0 0 1 1 1 1 EF-hand domain EF-hand_1 PF00036.32 AIN96067.1 - 0.012 15.1 0.0 0.032 13.8 0.0 1.7 1 0 0 1 1 1 0 EF hand EF-hand_7 PF13499.6 AIN96067.1 - 0.022 15.2 0.0 0.04 14.4 0.0 1.4 1 0 0 1 1 1 0 EF-hand domain pair RIIa PF02197.17 AIN96067.1 - 0.13 11.9 0.0 0.22 11.2 0.0 1.3 1 0 0 1 1 1 0 Regulatory subunit of type II PKA R-subunit KASH_CCD PF14662.6 AIN96068.1 - 2e-05 24.5 91.5 0.036 13.9 18.7 5.6 2 2 1 4 4 4 3 Coiled-coil region of CCDC155 or KASH DivIVA PF05103.13 AIN96068.1 - 0.015 15.4 2.5 0.015 15.4 2.5 6.9 3 1 3 7 7 7 0 DivIVA protein ADIP PF11559.8 AIN96068.1 - 1.8 8.6 95.4 0.062 13.4 16.4 8.2 3 2 6 9 9 9 0 Afadin- and alpha -actinin-Binding CENP-F_leu_zip PF10473.9 AIN96068.1 - 7.9 6.5 97.6 0.24 11.4 20.2 7.3 2 2 3 6 6 6 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 MMS19_N PF14500.6 AIN96071.1 - 2.1e-42 145.5 7.2 5.6e-42 144.1 6.0 2.2 2 0 0 2 2 2 1 Dos2-interacting transcription regulator of RNA-Pol-II CLASP_N PF12348.8 AIN96071.1 - 0.0039 16.8 2.2 0.0044 16.6 0.4 2.0 2 0 0 2 2 2 1 CLASP N terminal Thymidylate_kin PF02223.17 AIN96072.1 - 4.1e-13 49.4 0.0 1.4e-12 47.7 0.0 1.8 1 1 0 1 1 1 1 Thymidylate kinase Ribosomal_L35Ae PF01247.18 AIN96073.1 - 3.1e-32 110.6 0.6 5e-32 109.9 0.6 1.3 1 0 0 1 1 1 1 Ribosomal protein L35Ae RimM PF01782.18 AIN96073.1 - 3e-05 24.2 0.2 0.076 13.3 0.0 2.4 2 1 0 2 2 2 2 RimM N-terminal domain adh_short PF00106.25 AIN96075.1 - 9.1e-29 100.3 0.0 2.6e-25 89.0 0.0 2.3 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 AIN96075.1 - 9.9e-21 74.4 0.0 5.3e-16 58.9 0.0 2.2 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 AIN96075.1 - 0.0013 18.6 0.0 0.0027 17.7 0.0 1.5 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 AIN96075.1 - 0.0073 15.8 0.0 0.012 15.1 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family SRP40_C PF05022.12 AIN96076.1 - 2.7e-12 47.3 1.2 6.6e-12 46.1 0.9 1.9 2 0 0 2 2 2 1 SRP40, C-terminal domain SPESP1 PF15754.5 AIN96076.1 - 0.11 11.6 4.8 0.16 11.1 4.8 1.2 1 0 0 1 1 1 0 Sperm equatorial segment protein 1 WD40 PF00400.32 AIN96077.1 - 2.8e-30 103.9 28.1 3.4e-07 30.8 0.6 7.3 7 1 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 AIN96077.1 - 5.6e-05 23.4 0.1 0.0066 16.7 0.0 3.7 2 2 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain PSP1 PF04468.12 AIN96078.1 - 3.9e-23 81.5 0.9 6.3e-23 80.9 0.9 1.3 1 0 0 1 1 1 1 PSP1 C-terminal conserved region PI3K_P85_iSH2 PF16454.5 AIN96079.1 - 0.28 10.8 6.9 0.74 9.4 6.9 1.7 1 1 0 1 1 1 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain Pex19 PF04614.12 AIN96079.1 - 0.44 10.3 6.4 0.31 10.8 4.1 1.8 2 0 0 2 2 2 0 Pex19 protein family DUF1151 PF06625.11 AIN96079.1 - 3.5 7.6 12.8 6.6 6.7 0.9 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1151) FlxA PF14282.6 AIN96079.1 - 6.7 6.8 12.9 4.8 7.2 8.3 2.6 1 1 1 2 2 2 0 FlxA-like protein Helicase_C PF00271.31 AIN96080.1 - 4.5e-13 49.5 0.1 1.4e-12 47.9 0.1 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 AIN96080.1 - 3.4e-11 43.2 0.2 1.2e-08 34.9 0.0 2.7 3 0 0 3 3 3 2 DEAD/DEAH box helicase DUF2046 PF09755.9 AIN96082.1 - 0.012 14.9 3.4 0.012 14.9 3.4 3.1 2 1 1 3 3 3 0 Uncharacterized conserved protein H4 (DUF2046) Exonuc_VII_L PF02601.15 AIN96082.1 - 0.53 9.8 23.6 2.5 7.6 1.9 2.4 2 0 0 2 2 2 0 Exonuclease VII, large subunit CENP-K PF11802.8 AIN96082.1 - 2.2 7.8 24.8 4.3 6.8 1.9 2.2 2 0 0 2 2 2 0 Centromere-associated protein K XRN_M PF17846.1 AIN96082.1 - 7.2 5.4 8.1 3.3 6.6 0.9 2.1 2 0 0 2 2 2 0 Xrn1 helical domain Ribosomal_S15 PF00312.22 AIN96082.1 - 8.4 6.7 11.6 0.41 10.9 5.0 2.3 2 1 0 2 2 2 0 Ribosomal protein S15 HI0933_like PF03486.14 AIN96082.1 - 9 4.9 8.2 6 5.5 0.3 2.2 2 0 0 2 2 2 0 HI0933-like protein GDA1_CD39 PF01150.17 AIN96083.1 - 4.7e-64 216.6 0.0 1.4e-63 215.1 0.0 1.7 1 1 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family C1ORF64 PF15547.6 AIN96083.1 - 0.17 12.3 1.0 0.74 10.3 1.0 1.9 1 1 1 2 2 2 0 Steroid receptor-associated and regulated protein LRR_8 PF13855.6 AIN96084.1 - 6.7e-13 48.2 11.1 4.6e-08 32.7 7.6 2.3 1 1 1 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 AIN96084.1 - 1.4e-12 47.6 7.5 1.6e-05 25.1 0.4 3.3 3 0 0 3 3 3 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 AIN96084.1 - 3.5e-07 29.8 7.8 2.2 9.1 0.6 5.8 6 0 0 6 6 6 3 Leucine Rich Repeat LRR_9 PF14580.6 AIN96084.1 - 0.069 12.6 0.1 0.11 12.0 0.1 1.3 1 0 0 1 1 1 0 Leucine-rich repeat PDZ_6 PF17820.1 AIN96085.1 - 2.9e-09 36.7 0.1 7.9e-09 35.2 0.1 1.8 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 AIN96085.1 - 8.4e-06 26.0 0.0 1.8e-05 25.0 0.0 1.5 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 AIN96085.1 - 0.00089 19.5 0.0 0.0022 18.3 0.0 1.6 1 0 0 1 1 1 1 PDZ domain MORN PF02493.20 AIN96086.1 - 2.1e-19 68.2 16.8 1e-06 28.3 0.5 4.6 4 0 0 4 4 4 4 MORN repeat Pkinase PF00069.25 AIN96087.1 - 7.8e-59 199.2 0.0 1e-58 198.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 AIN96087.1 - 2.2e-28 99.3 0.0 4.1e-28 98.4 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 AIN96087.1 - 9.1e-08 31.4 0.1 1.3e-07 30.9 0.1 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 AIN96087.1 - 1.3e-05 24.6 0.7 2.9e-05 23.5 0.7 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 AIN96087.1 - 0.00013 22.0 0.9 0.00022 21.2 0.9 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 AIN96087.1 - 0.029 14.0 1.4 0.21 11.2 0.4 2.4 2 0 0 2 2 2 0 RIO1 family Pkinase_fungal PF17667.1 AIN96087.1 - 0.032 13.0 0.6 0.056 12.2 0.6 1.3 1 0 0 1 1 1 0 Fungal protein kinase Kinase-like PF14531.6 AIN96087.1 - 0.049 12.9 0.0 0.11 11.8 0.0 1.7 1 1 0 1 1 1 0 Kinase-like Nop PF01798.18 AIN96088.1 - 5.1e-79 265.0 0.0 6.9e-79 264.5 0.0 1.2 1 0 0 1 1 1 1 snoRNA binding domain, fibrillarin NOP5NT PF08156.13 AIN96088.1 - 2.8e-16 59.6 0.0 9.8e-16 57.9 0.0 2.0 1 0 0 1 1 1 1 NOP5NT (NUC127) domain Amastin PF07344.11 AIN96091.1 - 1.9e-37 128.5 21.2 7.8e-25 87.5 6.8 2.5 2 1 0 2 2 2 2 Amastin surface glycoprotein PglL_A PF15864.5 AIN96091.1 - 1.6 8.5 5.6 14 5.6 0.5 3.1 2 0 0 2 2 2 0 Protein glycosylation ligase Amastin PF07344.11 AIN96092.1 - 7.7e-42 142.8 25.7 6.9e-26 90.9 15.6 2.3 2 0 0 2 2 2 2 Amastin surface glycoprotein Lysis_col PF02402.16 AIN96092.1 - 0.002 17.8 0.1 0.01 15.5 0.0 2.3 2 0 0 2 2 2 1 Lysis protein CaM_binding PF07839.11 AIN96093.1 - 1.7 9.4 10.2 0.5 11.1 4.8 2.5 2 0 0 2 2 2 0 Plant calmodulin-binding domain Pterin_4a PF01329.19 AIN96094.1 - 1.3e-08 34.9 0.0 5.7e-08 32.8 0.0 2.1 2 1 0 2 2 2 1 Pterin 4 alpha carbinolamine dehydratase COPI_assoc PF08507.10 AIN96095.1 - 4.7e-10 39.6 12.9 5.4e-10 39.4 12.9 1.0 1 0 0 1 1 1 1 COPI associated protein RNase_T PF00929.24 AIN96096.1 - 2.9e-09 37.7 0.0 4.8e-09 37.0 0.0 1.3 1 0 0 1 1 1 1 Exonuclease CCDC106 PF15794.5 AIN96097.1 - 0.29 10.8 4.2 0.1 12.3 0.5 2.2 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 106 DUF4200 PF13863.6 AIN96097.1 - 0.45 10.9 10.2 0.82 10.1 1.8 3.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) Iso_dh PF00180.20 AIN96098.1 - 3.3e-72 243.5 0.0 3.8e-72 243.3 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase FAM193_C PF15914.5 AIN96098.1 - 0.056 13.2 1.0 1.5 8.6 0.0 2.9 3 0 0 3 3 3 0 FAM193 family C-terminal Vps5 PF09325.10 AIN96099.1 - 0.048 13.2 7.1 0.084 12.4 7.1 1.3 1 0 0 1 1 1 0 Vps5 C terminal like DUF3584 PF12128.8 AIN96099.1 - 0.078 10.5 13.0 0.11 10.0 13.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DUF2615 PF11027.8 AIN96099.1 - 0.13 12.4 0.4 7.8 6.7 0.0 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2615) UPF0242 PF06785.11 AIN96099.1 - 0.56 10.3 10.8 1.2 9.3 10.8 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Fmp27_WPPW PF10359.9 AIN96099.1 - 0.94 8.3 6.8 1.5 7.5 6.8 1.3 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain Allexi_40kDa PF05549.11 AIN96099.1 - 1.9 8.0 5.7 3.7 7.0 5.2 1.7 1 1 0 1 1 1 0 Allexivirus 40kDa protein SlyX PF04102.12 AIN96099.1 - 2.6 8.7 21.2 0.042 14.5 8.2 4.0 4 0 0 4 4 4 0 SlyX Corona_S2 PF01601.16 AIN96099.1 - 4.2 5.7 4.4 6 5.2 4.4 1.1 1 0 0 1 1 1 0 Coronavirus S2 glycoprotein Spc24 PF08286.11 AIN96099.1 - 8.4 6.7 8.8 1.2 9.4 4.3 1.9 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 V_ATPase_I PF01496.19 AIN96099.1 - 9 4.1 6.3 13 3.5 6.3 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Sec23_trunk PF04811.15 AIN96100.1 - 6e-40 137.3 0.0 4e-19 69.1 0.0 2.2 1 1 1 2 2 2 2 Sec23/Sec24 trunk domain Sec23_helical PF04815.15 AIN96100.1 - 6.7e-21 74.1 0.1 2.9e-19 68.8 0.0 2.9 3 0 0 3 3 3 1 Sec23/Sec24 helical domain Sec23_BS PF08033.12 AIN96100.1 - 4.9e-18 65.7 0.2 1.2e-17 64.4 0.0 1.8 2 0 0 2 2 2 1 Sec23/Sec24 beta-sandwich domain Gelsolin PF00626.22 AIN96100.1 - 4e-06 26.7 0.0 8.3e-06 25.6 0.0 1.5 1 0 0 1 1 1 1 Gelsolin repeat zf-Sec23_Sec24 PF04810.15 AIN96100.1 - 0.023 14.7 6.2 0.049 13.7 6.2 1.6 1 0 0 1 1 1 0 Sec23/Sec24 zinc finger JAB PF01398.21 AIN96102.1 - 0.013 15.5 0.0 0.035 14.1 0.0 1.7 1 1 0 1 1 1 0 JAB1/Mov34/MPN/PAD-1 ubiquitin protease DUF348 PF03990.14 AIN96102.1 - 0.11 12.3 0.2 0.36 10.6 0.0 2.0 2 0 0 2 2 2 0 G5-linked-Ubiquitin-like domain BT1 PF03092.16 AIN96103.1 - 7.5e-254 842.8 5.0 8.6e-254 842.6 5.0 1.0 1 0 0 1 1 1 1 BT1 family BT1 PF03092.16 AIN96104.1 - 1.5e-255 848.4 8.3 1.7e-255 848.2 8.3 1.0 1 0 0 1 1 1 1 BT1 family Ost5 PF05251.12 AIN96104.1 - 3.9 7.8 10.2 5.9 7.2 0.1 3.3 3 0 0 3 3 3 0 Oligosaccharyltransferase subunit 5 Dak1 PF02733.17 AIN96105.1 - 2.7e-91 305.7 1.5 4e-91 305.2 1.5 1.2 1 0 0 1 1 1 1 Dak1 domain Dak2 PF02734.17 AIN96105.1 - 2.8e-38 131.5 2.6 2.8e-38 131.5 2.6 1.8 2 0 0 2 2 2 1 DAK2 domain zf-C3HC4_3 PF13920.6 AIN96107.1 - 1.5e-05 24.7 16.1 1.5e-05 24.7 16.1 2.1 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 AIN96107.1 - 0.027 14.4 11.5 0.027 14.4 11.5 1.7 2 1 0 2 2 2 0 zinc-RING finger domain Prok-RING_4 PF14447.6 AIN96107.1 - 0.26 11.2 13.0 3 7.8 13.0 2.2 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 zf-C3HC4_3 PF13920.6 AIN96108.1 - 2.1e-06 27.5 17.3 8.4e-06 25.5 17.3 1.8 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 AIN96108.1 - 0.06 13.3 13.7 0.15 12.0 13.7 1.6 1 1 0 1 1 1 0 zinc-RING finger domain Prok-RING_4 PF14447.6 AIN96108.1 - 6.9 6.6 16.9 75 3.3 16.9 2.1 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 4F5 PF04419.14 AIN96109.1 - 4.3e-08 33.9 6.1 4.3e-08 33.9 6.1 1.4 2 0 0 2 2 2 1 4F5 protein family zf-met2 PF12907.7 AIN96109.1 - 3.2e-05 24.0 0.2 3.2e-05 24.0 0.2 1.7 2 0 0 2 2 2 1 Zinc-binding zf-H2C2_2 PF13465.6 AIN96109.1 - 0.025 15.0 1.6 0.55 10.8 0.3 2.4 2 0 0 2 2 2 0 Zinc-finger double domain zf-C2H2_4 PF13894.6 AIN96109.1 - 0.095 13.6 0.9 0.57 11.2 0.1 2.3 2 0 0 2 2 2 0 C2H2-type zinc finger Peptidase_M8 PF01457.16 AIN96110.1 - 2.6e-271 900.9 0.8 2.9e-271 900.7 0.8 1.0 1 0 0 1 1 1 1 Leishmanolysin Peptidase_M8 PF01457.16 AIN96111.1 - 8.8e-255 846.4 3.9 1e-254 846.2 3.9 1.0 1 0 0 1 1 1 1 Leishmanolysin Peptidase_M8 PF01457.16 AIN96112.1 - 7e-247 820.3 0.0 7.9e-247 820.1 0.0 1.0 1 0 0 1 1 1 1 Leishmanolysin Peptidase_M8 PF01457.16 AIN96113.1 - 1.9e-273 908.0 0.9 2.1e-273 907.8 0.9 1.0 1 0 0 1 1 1 1 Leishmanolysin Pkinase PF00069.25 AIN96114.1 - 1.6e-63 214.5 0.0 1.9e-63 214.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 AIN96114.1 - 8.5e-28 97.3 0.0 8.9e-27 94.0 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 AIN96114.1 - 0.00091 18.6 0.1 0.0015 18.0 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 AIN96114.1 - 0.0028 17.0 0.0 0.0042 16.4 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Baculo_11_kDa PF06143.11 AIN96115.1 - 0.27 10.8 0.6 0.57 9.8 0.6 1.5 1 0 0 1 1 1 0 Baculovirus 11 kDa family Thionin PF00321.17 AIN96115.1 - 5 7.7 7.7 26 5.4 0.4 3.8 3 0 0 3 3 3 0 Plant thionin NAD_Gly3P_dh_C PF07479.14 AIN96116.1 - 7e-47 159.3 1.4 5.4e-46 156.4 0.2 2.1 2 0 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus NAD_Gly3P_dh_N PF01210.23 AIN96116.1 - 2.6e-43 147.7 0.1 3.9e-43 147.1 0.1 1.2 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus UDPG_MGDP_dh_N PF03721.14 AIN96116.1 - 2e-05 24.2 0.0 4e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain F420_oxidored PF03807.17 AIN96116.1 - 0.0064 17.1 0.0 0.016 15.8 0.0 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent DUF1188 PF06690.11 AIN96116.1 - 0.0098 15.5 0.1 0.019 14.5 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1188) NAD_binding_2 PF03446.15 AIN96116.1 - 0.021 15.0 0.1 0.082 13.1 0.0 2.0 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase 3HCDH_N PF02737.18 AIN96116.1 - 0.033 14.1 0.2 0.068 13.0 0.0 1.6 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain HEAT_EZ PF13513.6 AIN96117.1 - 0.036 14.6 1.0 1.1 9.8 0.2 3.3 2 0 0 2 2 2 0 HEAT-like repeat GTP_EFTU PF00009.27 AIN96118.1 - 0.0021 17.6 0.0 0.014 14.9 0.0 2.5 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain DUF1281 PF06924.11 AIN96118.1 - 0.0045 16.5 0.1 0.18 11.3 0.1 2.6 2 0 0 2 2 2 1 Protein of unknown function (DUF1281) Pox_A_type_inc PF04508.12 AIN96118.1 - 0.07 13.0 3.9 0.16 11.9 0.9 3.1 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat Bap31_Bap29_C PF18035.1 AIN96118.1 - 0.079 13.0 0.1 0.079 13.0 0.1 4.1 5 0 0 5 5 5 0 Bap31/Bap29 cytoplasmic coiled-coil domain HU-CCDC81_bac_2 PF18175.1 AIN96118.1 - 0.48 10.3 3.5 1.5 8.7 0.1 3.5 3 1 1 4 4 4 0 CCDC81-like prokaryotic HU domain 2 ADH_zinc_N PF00107.26 AIN96121.1 - 3.7e-15 56.1 0.0 6.7e-15 55.2 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 AIN96121.1 - 4.6e-08 34.2 0.0 7.2e-08 33.6 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 AIN96121.1 - 5.3e-08 32.7 0.1 2.9e-07 30.3 0.1 2.2 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 AIN96122.1 - 6.2e-16 58.6 1.0 1.1e-15 57.7 0.0 1.9 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 AIN96122.1 - 6.6e-15 56.3 0.0 1.4e-14 55.3 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 AIN96122.1 - 7.9e-05 22.5 0.0 0.00058 19.7 0.0 2.4 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain CAF1A PF12253.8 AIN96123.1 - 4.9e-08 33.0 2.6 4.9e-08 33.0 2.6 3.9 3 1 0 3 3 3 1 Chromatin assembly factor 1 subunit A SDA1 PF05285.12 AIN96123.1 - 2.3 7.5 32.8 1.2 8.5 0.5 3.2 3 0 0 3 3 3 0 SDA1 Borrelia_P83 PF05262.11 AIN96123.1 - 5.4 5.4 23.5 0.057 11.9 13.5 2.0 2 0 0 2 2 2 0 Borrelia P83/100 protein ABC1 PF03109.16 AIN96125.1 - 9.1e-23 80.7 0.0 1.9e-22 79.7 0.0 1.5 1 0 0 1 1 1 1 ABC1 family Endonuclease_NS PF01223.23 AIN96126.1 - 2.9e-49 167.9 0.0 5.8e-49 166.9 0.0 1.4 1 1 0 1 1 1 1 DNA/RNA non-specific endonuclease Endonuclea_NS_2 PF13930.6 AIN96126.1 - 0.063 13.4 0.1 0.17 12.0 0.1 1.6 1 1 0 1 1 1 0 DNA/RNA non-specific endonuclease B277 PF17623.2 AIN96126.1 - 1.8 7.6 3.7 0.37 9.8 0.1 1.6 2 0 0 2 2 2 0 Domain of unknown function Rax2 PF12768.7 AIN96127.1 - 0.0071 15.8 0.0 0.015 14.8 0.0 1.5 1 0 0 1 1 1 1 Cortical protein marker for cell polarity zf-CCCH PF00642.24 AIN96129.1 - 0.00025 20.9 3.1 0.00044 20.1 3.1 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 AIN96129.1 - 0.025 14.6 3.1 0.045 13.8 3.1 1.4 1 0 0 1 1 1 0 Zinc finger domain DUF1751 PF08551.10 AIN96132.1 - 0.001 19.6 1.6 0.0061 17.1 0.3 2.2 2 0 0 2 2 2 1 Eukaryotic integral membrane protein (DUF1751) CDC45 PF02724.14 AIN96132.1 - 0.1 10.8 2.5 0.14 10.5 2.5 1.1 1 0 0 1 1 1 0 CDC45-like protein Sec62 PF03839.16 AIN96132.1 - 0.19 11.2 1.1 0.28 10.7 1.1 1.2 1 0 0 1 1 1 0 Translocation protein Sec62 MCM_bind PF09739.9 AIN96132.1 - 1.2 7.4 2.8 1.6 7.1 2.8 1.1 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor Paf1 PF03985.13 AIN96132.1 - 3.9 6.4 8.9 5.2 6.0 8.9 1.1 1 0 0 1 1 1 0 Paf1 NPR3 PF03666.13 AIN96132.1 - 4.3 6.0 6.2 5.7 5.6 6.2 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 CCDC106 PF15794.5 AIN96132.1 - 5.6 6.6 8.6 7.8 6.1 8.6 1.1 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 HEAT PF02985.22 AIN96133.1 - 9.9e-09 34.7 29.6 0.013 15.6 0.1 8.9 7 0 0 7 7 7 4 HEAT repeat HEAT_2 PF13646.6 AIN96133.1 - 0.002 18.5 33.0 0.33 11.4 0.0 9.4 10 0 0 10 10 10 2 HEAT repeats HEAT_EZ PF13513.6 AIN96133.1 - 0.033 14.7 21.3 3.2 8.4 0.2 7.8 7 0 0 7 7 7 0 HEAT-like repeat Vac14_Fab1_bd PF12755.7 AIN96133.1 - 0.069 13.7 0.1 1 10.0 0.0 3.0 4 0 0 4 4 4 0 Vacuolar 14 Fab1-binding region RRM_1 PF00076.22 AIN96134.1 - 2.4e-42 142.6 0.3 6.3e-16 58.0 0.0 6.1 5 1 0 5 5 5 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 AIN96134.1 - 3e-05 23.6 0.0 0.057 13.0 0.0 3.1 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 AIN96134.1 - 0.0004 20.2 0.0 0.11 12.3 0.0 3.6 3 0 0 3 3 3 1 Occluded RNA-recognition motif RRM_7 PF16367.5 AIN96134.1 - 0.0064 16.6 0.0 0.22 11.7 0.0 3.3 4 0 0 4 4 4 1 RNA recognition motif RRM_Rrp7 PF17799.1 AIN96134.1 - 0.011 15.5 0.1 3.3 7.5 0.0 3.6 4 0 0 4 4 4 0 Rrp7 RRM-like N-terminal domain Nup35_RRM_2 PF14605.6 AIN96134.1 - 0.13 12.3 0.0 1.2 9.1 0.0 2.6 3 0 0 3 3 3 0 Nup53/35/40-type RNA recognition motif Aa_trans PF01490.18 AIN96135.1 - 1e-38 133.2 34.1 1.2e-38 132.9 34.1 1.2 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein dCMP_cyt_deam_1 PF00383.23 AIN96136.1 - 1e-12 47.8 2.8 3.6e-10 39.6 2.8 2.9 1 1 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 AIN96136.1 - 1e-11 44.8 0.6 2.2e-05 24.3 0.0 3.1 3 0 0 3 3 3 3 MafB19-like deaminase FAD_binding_5 PF00941.21 AIN96136.1 - 0.05 13.3 0.2 0.072 12.8 0.2 1.2 1 0 0 1 1 1 0 FAD binding domain in molybdopterin dehydrogenase Bd3614-deam PF14439.6 AIN96136.1 - 0.24 11.5 2.5 0.81 9.8 2.5 2.0 1 1 0 1 1 1 0 Bd3614-like deaminase Spt20 PF12090.8 AIN96137.1 - 0.55 9.8 8.0 0.67 9.5 8.0 1.2 1 0 0 1 1 1 0 Spt20 family DUF1482 PF07358.11 AIN96137.1 - 3.8 7.5 5.7 16 5.5 6.3 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF1482) HscB_4_cys PF18256.1 AIN96138.1 - 0.3 10.9 2.1 0.47 10.3 0.1 2.5 2 0 0 2 2 2 0 Co-chaperone HscB tetracysteine metal binding motif CAMSAP_CC1 PF17095.5 AIN96138.1 - 6.3 6.7 10.4 0.039 13.8 1.3 2.1 2 0 0 2 2 2 0 Spectrin-binding region of Ca2+-Calmodulin MTHFR PF02219.17 AIN96139.1 - 0.067 12.5 0.0 18 4.6 0.0 2.9 3 0 0 3 3 3 0 Methylenetetrahydrofolate reductase RPA_C PF08784.11 AIN96139.1 - 0.15 12.7 0.0 0.4 11.4 0.0 1.7 1 0 0 1 1 1 0 Replication protein A C terminal WD40 PF00400.32 AIN96141.1 - 6.3e-65 213.6 17.1 1.3e-08 35.3 0.1 8.1 8 0 0 8 8 8 8 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 AIN96141.1 - 5e-23 81.2 2.8 6.2e-05 23.2 0.0 7.4 1 1 6 7 7 7 6 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 AIN96141.1 - 6.2e-13 48.7 2.9 0.037 13.4 0.1 6.5 3 3 4 7 7 7 5 WD40-like domain Nup160 PF11715.8 AIN96141.1 - 6.4e-11 41.6 12.6 0.0037 16.0 0.1 5.7 2 1 4 6 6 6 4 Nucleoporin Nup120/160 eIF2A PF08662.11 AIN96141.1 - 6.1e-09 36.0 2.5 0.00016 21.6 0.1 3.2 1 1 2 3 3 3 3 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 AIN96141.1 - 0.0019 17.3 9.3 1.2 8.0 1.6 4.9 1 1 4 5 5 5 2 WD40 region of Ge1, enhancer of mRNA-decapping protein DUF4934 PF16288.5 AIN96141.1 - 0.059 13.3 1.0 7.4 6.5 0.0 3.7 4 1 0 4 4 4 0 Domain of unknown function (DUF4934) Invasin_D3 PF09134.10 AIN96141.1 - 0.25 11.7 1.8 1.2 9.5 0.2 2.7 2 1 1 3 3 3 0 Invasin, domain 3 DFRP_C PF16543.5 AIN96142.1 - 2.8e-12 47.0 7.5 2.8e-12 47.0 7.5 2.7 2 1 0 2 2 2 1 DRG Family Regulatory Proteins, Tma46 BetaGal_dom3 PF13363.6 AIN96144.1 - 0.048 13.2 0.1 0.18 11.4 0.0 2.0 2 0 0 2 2 2 0 Beta-galactosidase, domain 3 TPR_2 PF07719.17 AIN96145.1 - 5.4e-05 23.0 1.6 0.22 11.7 0.0 3.9 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.6 AIN96145.1 - 0.00028 21.1 5.1 0.001 19.3 5.1 2.1 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_1 PF00515.28 AIN96145.1 - 0.0021 17.8 0.5 0.11 12.4 0.0 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat DUF2153 PF09921.9 AIN96145.1 - 0.027 14.3 0.2 0.058 13.2 0.2 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2153) TPR_8 PF13181.6 AIN96145.1 - 0.07 13.4 1.0 20 5.7 0.1 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_10 PF13374.6 AIN96145.1 - 0.077 12.9 9.8 0.32 10.9 3.1 3.2 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_9 PF13371.6 AIN96145.1 - 0.15 12.2 4.3 4.8 7.4 0.0 2.8 1 1 1 2 2 2 0 Tetratricopeptide repeat Pkinase PF00069.25 AIN96146.1 - 1.2e-22 80.6 0.0 8e-18 64.7 0.0 2.4 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 AIN96146.1 - 2.3e-05 23.8 0.0 0.0071 15.7 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase A_deaminase PF00962.22 AIN96147.1 - 2.2e-10 40.4 1.8 4.2e-05 23.0 0.1 3.3 3 0 0 3 3 3 3 Adenosine/AMP deaminase NTF2 PF02136.20 AIN96148.1 - 6.6e-26 91.2 0.3 7.2e-26 91.1 0.3 1.0 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain DUF4440 PF14534.6 AIN96148.1 - 0.00023 21.6 0.0 0.00027 21.3 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) Lumazine_bd_2 PF12893.7 AIN96148.1 - 0.027 15.2 0.1 0.046 14.4 0.1 1.4 1 0 0 1 1 1 0 Putative lumazine-binding Nop16 PF09420.10 AIN96149.1 - 3.4e-14 53.4 2.2 3.4e-11 43.6 0.8 2.1 1 1 1 2 2 2 2 Ribosome biogenesis protein Nop16 YpjP PF14005.6 AIN96149.1 - 0.069 13.2 0.1 0.1 12.7 0.1 1.2 1 0 0 1 1 1 0 YpjP-like protein FKBP_C PF00254.28 AIN96151.1 - 3.1e-25 88.3 0.0 4.2e-25 87.9 0.0 1.2 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase DUF2895 PF11444.8 AIN96151.1 - 0.15 11.4 0.0 0.2 11.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2895) IQ PF00612.27 AIN96152.1 - 9.9e-05 21.8 51.0 0.28 11.1 0.5 9.4 8 0 0 8 8 8 7 IQ calmodulin-binding motif Ras PF00071.22 AIN96153.1 - 4.3e-58 195.5 0.1 5e-58 195.3 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 AIN96153.1 - 1.8e-32 112.1 0.0 3.1e-32 111.3 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 AIN96153.1 - 3.8e-14 52.5 0.0 4.7e-14 52.2 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 AIN96153.1 - 8.1e-06 25.5 0.0 2.1e-05 24.2 0.0 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 AIN96153.1 - 1e-05 25.6 0.2 2.4e-05 24.4 0.0 1.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase Ploopntkinase3 PF18751.1 AIN96153.1 - 0.00044 20.2 0.0 0.97 9.3 0.0 2.2 2 0 0 2 2 2 2 P-loop Nucleotide Kinase3 RsgA_GTPase PF03193.16 AIN96153.1 - 0.00055 19.9 0.5 0.053 13.4 0.1 2.4 1 1 0 2 2 2 1 RsgA GTPase DLIC PF05783.11 AIN96153.1 - 0.0034 16.3 0.0 1.1 8.0 0.0 2.1 1 1 1 2 2 2 2 Dynein light intermediate chain (DLIC) SRPRB PF09439.10 AIN96153.1 - 0.0053 16.2 0.2 0.0095 15.4 0.0 1.5 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit AAA_22 PF13401.6 AIN96153.1 - 0.0082 16.4 0.0 0.015 15.5 0.0 1.7 1 1 0 1 1 1 1 AAA domain ATP_bind_1 PF03029.17 AIN96153.1 - 0.013 15.3 0.1 0.072 12.9 0.0 1.9 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein AAA_7 PF12775.7 AIN96153.1 - 0.02 14.4 0.1 0.031 13.8 0.1 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_24 PF13479.6 AIN96153.1 - 0.025 14.3 0.0 0.036 13.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain Gtr1_RagA PF04670.12 AIN96153.1 - 0.026 13.9 0.1 0.033 13.6 0.1 1.3 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region FeoB_N PF02421.18 AIN96153.1 - 0.029 13.9 0.0 0.059 12.9 0.0 1.5 1 0 0 1 1 1 0 Ferrous iron transport protein B Amidase02_C PF12123.8 AIN96153.1 - 0.032 13.9 0.1 0.27 10.9 0.0 2.3 2 0 0 2 2 2 0 N-acetylmuramoyl-l-alanine amidase Septin PF00735.18 AIN96153.1 - 0.033 13.5 0.1 0.055 12.7 0.1 1.3 1 0 0 1 1 1 0 Septin ABC_tran PF00005.27 AIN96153.1 - 0.072 13.6 0.0 0.093 13.2 0.0 1.4 1 1 0 1 1 1 0 ABC transporter DUF2101 PF09874.9 AIN96154.1 - 9.5 5.9 13.1 1.1 8.9 8.9 1.5 2 0 0 2 2 2 0 Predicted membrane protein (DUF2101) DUF4064 PF13273.6 AIN96155.1 - 0.3 11.4 0.0 0.3 11.4 0.0 4.5 4 0 0 4 4 4 0 Protein of unknown function (DUF4064) CALM_bind PF16025.5 AIN96156.1 - 0.17 12.4 1.2 0.45 11.0 1.2 1.7 1 0 0 1 1 1 0 Calcium-dependent calmodulin binding IF-2B PF01008.17 AIN96158.1 - 1.7e-42 145.6 0.0 4.8e-40 137.5 0.0 2.1 2 0 0 2 2 2 2 Initiation factor 2 subunit family Plk4_PB2 PF18409.1 AIN96159.1 - 0.026 15.2 6.0 1.2 9.9 1.5 3.2 2 1 0 2 2 2 0 Polo-like Kinase 4 Polo Box 2 Dishevelled PF02377.15 AIN96159.1 - 0.03 14.8 0.2 0.03 14.8 0.2 3.3 3 0 0 3 3 3 0 Dishevelled specific domain TetR_C_24 PF17932.1 AIN96159.1 - 0.053 13.8 0.7 0.053 13.8 0.7 2.9 2 1 1 3 3 3 0 Tetracyclin repressor-like, C-terminal domain DUF1382 PF07131.11 AIN96160.1 - 0.013 15.5 0.0 0.029 14.4 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1382) PNP_UDP_1 PF01048.20 AIN96161.1 - 2.7e-45 154.4 0.6 3.7e-45 154.0 0.6 1.1 1 0 0 1 1 1 1 Phosphorylase superfamily Mito_carr PF00153.27 AIN96162.1 - 2.2e-21 75.6 5.5 3.7e-08 33.2 0.6 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein RRM_1 PF00076.22 AIN96163.1 - 1.1e-06 28.3 0.0 2.3e-06 27.3 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) AP3D1 PF06375.11 AIN96163.1 - 0.14 12.4 6.4 0.32 11.2 6.4 1.6 1 0 0 1 1 1 0 AP-3 complex subunit delta-1 CH_2 PF06294.11 AIN96164.1 - 4.7e-24 84.3 0.0 9.3e-24 83.4 0.0 1.5 1 0 0 1 1 1 1 CH-like domain in sperm protein CAMSAP_CH PF11971.8 AIN96164.1 - 0.012 15.4 0.0 0.022 14.6 0.0 1.5 1 0 0 1 1 1 0 CAMSAP CH domain DnaJ PF00226.31 AIN96165.1 - 2e-06 27.8 0.5 3.8e-06 26.9 0.5 1.4 1 0 0 1 1 1 1 DnaJ domain Autoind_synth PF00765.17 AIN96166.1 - 0.02 14.4 0.0 0.034 13.7 0.0 1.2 1 0 0 1 1 1 0 Autoinducer synthase YABBY PF04690.13 AIN96166.1 - 0.1 13.2 0.0 0.17 12.5 0.0 1.3 1 0 0 1 1 1 0 YABBY protein PAGK PF15284.6 AIN96166.1 - 0.18 11.8 0.0 0.34 10.9 0.0 1.4 1 0 0 1 1 1 0 Phage-encoded virulence factor EMP24_GP25L PF01105.24 AIN96167.1 - 0.26 11.2 7.1 0.45 10.4 0.0 3.2 3 0 0 3 3 3 0 emp24/gp25L/p24 family/GOLD NPV_P10 PF05531.12 AIN96167.1 - 0.61 10.6 0.1 0.61 10.6 0.1 3.7 5 0 0 5 5 5 0 Nucleopolyhedrovirus P10 protein MIF4G PF02854.19 AIN96168.1 - 1e-13 51.4 4.1 1.1e-13 51.3 0.6 2.5 3 0 0 3 3 3 1 MIF4G domain Herpes_BLRF2 PF05812.12 AIN96168.1 - 0.017 15.2 0.9 0.045 13.9 0.9 1.6 1 0 0 1 1 1 0 Herpesvirus BLRF2 protein DUF4041 PF13250.6 AIN96168.1 - 0.11 12.3 0.1 0.5 10.3 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4041) Sporozoite_P67 PF05642.11 AIN96168.1 - 0.89 7.6 3.2 1.4 6.9 3.2 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen DUF1104 PF06518.11 AIN96168.1 - 7.7 7.0 7.1 41 4.6 0.1 3.4 3 1 0 3 3 3 0 Protein of unknown function (DUF1104) LsmAD PF06741.13 AIN96171.1 - 4.7e-18 65.5 2.0 4.7e-18 65.5 2.0 1.9 2 0 0 2 2 2 1 LsmAD domain SM-ATX PF14438.6 AIN96171.1 - 4.3e-11 42.8 0.0 7.7e-11 42.0 0.0 1.4 1 0 0 1 1 1 1 Ataxin 2 SM domain TPR_2 PF07719.17 AIN96173.1 - 0.024 14.8 0.6 4.1 7.7 0.2 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF3730 PF12530.8 AIN96173.1 - 0.034 13.7 3.2 0.039 13.5 1.3 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3730) zf-C3HC4_3 PF13920.6 AIN96174.1 - 9.3e-16 57.4 12.0 1.8e-15 56.5 12.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 AIN96174.1 - 2.2e-09 37.0 11.6 4e-09 36.2 11.6 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 AIN96174.1 - 4.8e-06 26.8 13.1 1.1e-05 25.7 13.1 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 AIN96174.1 - 0.0077 16.1 14.5 0.017 14.9 14.5 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.6 AIN96174.1 - 0.087 12.6 8.6 0.17 11.7 8.6 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING_5 PF14634.6 AIN96174.1 - 0.099 12.6 12.5 0.24 11.4 12.5 1.7 1 0 0 1 1 1 0 zinc-RING finger domain zf-P11 PF03854.14 AIN96174.1 - 1.3 8.8 10.9 2.9 7.6 10.9 1.5 1 0 0 1 1 1 0 P-11 zinc finger TPH PF13868.6 AIN96175.1 - 7.5e-65 218.7 158.2 7.5e-65 218.7 158.2 2.0 1 1 1 2 2 2 1 Trichohyalin-plectin-homology domain Ras PF00071.22 AIN96176.1 - 1.8e-53 180.4 0.0 2.2e-53 180.2 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 AIN96176.1 - 7.5e-30 103.6 0.0 1.5e-29 102.7 0.0 1.5 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 AIN96176.1 - 1.4e-11 44.2 0.0 1.8e-11 43.8 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 AIN96176.1 - 3.3e-06 26.8 0.0 0.00044 19.9 0.0 2.2 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 AIN96176.1 - 1.5e-05 25.0 0.0 2.1e-05 24.6 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 AIN96176.1 - 0.00014 21.3 0.2 0.0002 20.8 0.2 1.5 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 AIN96176.1 - 0.00061 19.7 0.0 0.03 14.3 0.0 2.1 2 0 0 2 2 2 1 RsgA GTPase AAA_18 PF13238.6 AIN96176.1 - 0.0015 19.1 0.0 0.0057 17.2 0.0 1.9 2 0 0 2 2 2 1 AAA domain PduV-EutP PF10662.9 AIN96176.1 - 0.0028 17.4 0.0 0.016 14.9 0.0 2.0 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation AAA_16 PF13191.6 AIN96176.1 - 0.003 18.0 0.1 0.0071 16.8 0.1 1.8 1 1 0 1 1 1 1 AAA ATPase domain SRPRB PF09439.10 AIN96176.1 - 0.016 14.6 0.0 0.024 14.1 0.0 1.5 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_33 PF13671.6 AIN96176.1 - 0.019 15.1 0.0 0.036 14.2 0.0 1.4 1 1 0 1 1 1 0 AAA domain ATP_bind_1 PF03029.17 AIN96176.1 - 0.027 14.3 0.3 1.9 8.2 0.0 2.1 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein ABC_tran PF00005.27 AIN96176.1 - 0.028 14.9 0.0 0.065 13.7 0.0 1.7 1 1 0 1 1 1 0 ABC transporter AAA_22 PF13401.6 AIN96176.1 - 0.052 13.8 0.2 0.39 11.0 0.0 2.3 1 1 1 2 2 2 0 AAA domain RNA_helicase PF00910.22 AIN96176.1 - 0.053 13.9 0.0 0.17 12.3 0.0 1.8 2 0 0 2 2 2 0 RNA helicase Septin PF00735.18 AIN96176.1 - 0.095 12.0 0.0 0.18 11.0 0.0 1.4 1 0 0 1 1 1 0 Septin IIGP PF05049.13 AIN96176.1 - 0.1 11.6 0.0 0.18 10.9 0.0 1.4 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) DUF87 PF01935.17 AIN96176.1 - 0.19 11.8 0.5 4.5 7.3 0.1 2.0 2 0 0 2 2 2 0 Helicase HerA, central domain Ras PF00071.22 AIN96177.1 - 3.8e-46 156.7 0.0 4.4e-46 156.5 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 AIN96177.1 - 3.3e-26 91.9 0.0 5e-26 91.3 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 AIN96177.1 - 6.3e-07 29.0 0.0 7.1e-07 28.8 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 AIN96177.1 - 6.5e-05 22.6 0.0 0.0018 17.8 0.0 2.1 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 AIN96177.1 - 7.2e-05 22.2 0.0 8.4e-05 22.0 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 AIN96177.1 - 0.027 14.5 0.0 0.049 13.7 0.0 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase Gemini_mov PF01708.16 AIN96178.1 - 0.23 11.2 2.1 11 5.9 0.0 2.2 2 0 0 2 2 2 0 Geminivirus putative movement protein RIB43A PF05914.12 AIN96179.1 - 9e-74 248.5 63.5 1.1e-73 248.2 63.5 1.0 1 0 0 1 1 1 1 RIB43A zf-RanBP PF00641.18 AIN96180.1 - 3.1e-07 29.6 23.3 0.0011 18.3 1.9 3.4 3 0 0 3 3 3 3 Zn-finger in Ran binding protein and others DZR PF12773.7 AIN96180.1 - 3.1e-06 27.1 14.5 0.001 19.1 8.1 2.4 1 1 1 2 2 2 2 Double zinc ribbon Ima1_N PF09779.9 AIN96180.1 - 0.068 14.0 10.3 0.44 11.4 1.7 3.3 3 0 0 3 3 3 0 Ima1 N-terminal domain zinc-ribbon_6 PF10005.9 AIN96180.1 - 0.49 11.1 10.8 0.77 10.5 0.2 3.2 3 0 0 3 3 3 0 zinc-ribbon domain CSN7a_helixI PF18392.1 AIN96182.1 - 1.2 9.1 5.1 4.1 7.4 0.7 3.4 2 0 0 2 2 2 0 COP9 signalosome complex subunit 7a helix I domain Atx10homo_assoc PF09759.9 AIN96183.1 - 3.4e-23 81.5 0.0 5.6e-23 80.8 0.0 1.4 1 0 0 1 1 1 1 Spinocerebellar ataxia type 10 protein domain Methyltransf_23 PF13489.6 AIN96186.1 - 9.8e-20 71.0 0.0 1.4e-19 70.5 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 AIN96186.1 - 1.5e-06 28.7 0.1 7.1e-05 23.4 0.0 2.4 1 1 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 AIN96186.1 - 5.4e-06 27.1 0.0 7.1e-05 23.5 0.0 2.3 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 AIN96186.1 - 0.014 15.2 0.0 0.036 13.9 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_25 PF13649.6 AIN96186.1 - 0.036 14.8 0.0 2.6 8.8 0.0 2.6 1 1 0 2 2 2 0 Methyltransferase domain Yos9_DD PF17880.1 AIN96186.1 - 0.085 13.0 0.0 0.15 12.2 0.0 1.4 1 0 0 1 1 1 0 Yos9 dimerzation domain c-SKI_SMAD_bind PF08782.10 AIN96186.1 - 0.095 12.9 1.6 0.8 10.0 1.5 2.2 1 1 0 1 1 1 0 c-SKI Smad4 binding domain Ubie_methyltran PF01209.18 AIN96186.1 - 0.13 11.6 0.0 0.23 10.7 0.0 1.4 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family DUF1861 PF08950.10 AIN96187.1 - 5.9e-117 390.1 0.0 6.9e-117 389.9 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1861) DUF1861 PF08950.10 AIN96188.1 - 3.9e-115 384.2 0.0 4.5e-115 384.0 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1861) DUF1861 PF08950.10 AIN96189.1 - 3e-120 400.9 0.1 3.5e-120 400.7 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1861) DUF1861 PF08950.10 AIN96190.1 - 4.4e-121 403.7 0.0 5.1e-121 403.5 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1861) DUF1861 PF08950.10 AIN96191.1 - 3.4e-114 381.1 0.0 3.9e-114 380.9 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1861) DUF5565 PF17720.1 AIN96191.1 - 0.071 12.0 0.0 0.11 11.4 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5565) DUF1861 PF08950.10 AIN96192.1 - 5.3e-121 403.4 0.0 6.2e-121 403.2 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1861) PHO4 PF01384.20 AIN96193.1 - 3.8e-111 371.4 17.5 4.5e-111 371.1 17.5 1.1 1 0 0 1 1 1 1 Phosphate transporter family BT1 PF03092.16 AIN96194.1 - 8.9e-192 638.0 13.6 1.1e-191 637.7 13.6 1.0 1 0 0 1 1 1 1 BT1 family FA_desaturase PF00487.24 AIN96195.1 - 2.3e-26 93.2 26.5 2.3e-26 93.2 26.5 1.7 1 1 1 2 2 2 1 Fatty acid desaturase DUF3474 PF11960.8 AIN96195.1 - 0.051 13.8 0.0 0.13 12.5 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3474) DUF4200 PF13863.6 AIN96196.1 - 0.018 15.5 11.6 0.052 13.9 10.4 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) DUF2092 PF09865.9 AIN96196.1 - 0.036 13.4 0.0 0.046 13.1 0.0 1.2 1 0 0 1 1 1 0 Predicted periplasmic protein (DUF2092) TRAF_BIRC3_bd PF16673.5 AIN96196.1 - 0.045 13.5 6.0 1.2 8.9 3.7 2.9 2 1 0 2 2 2 0 TNF receptor-associated factor BIRC3 binding domain KLRAQ PF10205.9 AIN96196.1 - 0.1 12.9 9.8 0.14 12.4 1.8 2.3 1 1 1 2 2 2 0 Predicted coiled-coil domain-containing protein DUF4407 PF14362.6 AIN96196.1 - 0.16 11.3 5.3 0.24 10.7 5.2 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) DivIC PF04977.15 AIN96196.1 - 0.82 9.5 4.9 3.4 7.5 4.9 2.1 1 1 0 1 1 1 0 Septum formation initiator Plk4_PB2 PF18409.1 AIN96196.1 - 1.1 9.9 4.1 1.6 9.4 0.1 2.3 1 1 1 2 2 2 0 Polo-like Kinase 4 Polo Box 2 GIT_CC PF16559.5 AIN96196.1 - 1.6 8.7 7.3 3.4 7.6 0.2 3.7 3 2 1 4 4 4 0 GIT coiled-coil Rho guanine nucleotide exchange factor ZapB PF06005.12 AIN96196.1 - 3.5 8.1 12.1 2.1 8.8 2.1 3.1 1 1 1 2 2 2 0 Cell division protein ZapB Spc24 PF08286.11 AIN96196.1 - 3.9 7.8 7.0 21 5.4 7.0 2.1 1 1 0 1 1 1 0 Spc24 subunit of Ndc80 COPIIcoated_ERV PF07970.12 AIN96197.1 - 3.4e-34 118.6 0.0 1.3e-33 116.7 0.0 1.7 2 0 0 2 2 2 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.6 AIN96197.1 - 0.00017 21.9 0.0 0.00037 20.8 0.0 1.6 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) NMDAR2_C PF10565.9 AIN96197.1 - 0.22 10.4 0.9 0.3 9.9 0.9 1.1 1 0 0 1 1 1 0 N-methyl D-aspartate receptor 2B3 C-terminus Hexapep PF00132.24 AIN96198.1 - 2.8e-13 49.0 2.8 0.00017 21.2 0.0 3.3 2 1 1 3 3 3 3 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 AIN96198.1 - 0.099 12.4 4.6 7.1 6.5 0.2 3.2 2 1 1 3 3 3 0 Hexapeptide repeat of succinyl-transferase ABC_tran PF00005.27 AIN96199.1 - 3.3e-27 95.7 0.0 6.3e-27 94.8 0.0 1.5 2 0 0 2 2 2 1 ABC transporter AAA_21 PF13304.6 AIN96199.1 - 3.6e-05 23.7 1.4 0.0053 16.6 0.1 2.2 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 AIN96199.1 - 0.0012 18.4 0.1 0.011 15.2 0.0 2.0 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 AIN96199.1 - 0.0066 16.4 0.0 0.014 15.3 0.0 1.5 1 0 0 1 1 1 1 RsgA GTPase AAA_29 PF13555.6 AIN96199.1 - 0.019 14.7 0.1 0.039 13.7 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.6 AIN96199.1 - 0.033 14.6 0.7 0.063 13.7 0.1 1.9 2 1 0 2 2 2 0 AAA ATPase domain KDGP_aldolase PF07071.11 AIN96199.1 - 0.1 12.4 0.0 0.15 11.8 0.0 1.2 1 0 0 1 1 1 0 KDGP aldolase SbcCD_C PF13558.6 AIN96199.1 - 0.21 11.8 3.6 0.46 10.7 0.1 2.9 3 1 0 3 3 3 0 Putative exonuclease SbcCD, C subunit SNF2_N PF00176.23 AIN96200.1 - 2e-25 89.3 0.1 3.8e-25 88.4 0.1 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain HNH PF01844.23 AIN96200.1 - 6.6e-08 32.6 0.1 6.6e-08 32.6 0.1 2.8 2 0 0 2 2 2 1 HNH endonuclease Helicase_C PF00271.31 AIN96200.1 - 1.5e-05 25.3 0.0 3.2e-05 24.3 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HNH_5 PF14279.6 AIN96200.1 - 0.0007 19.4 0.2 0.0007 19.4 0.2 2.5 3 0 0 3 3 3 1 HNH endonuclease ResIII PF04851.15 AIN96200.1 - 0.0049 16.9 0.0 0.011 15.8 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Tenui_NS3 PF05310.12 AIN96200.1 - 0.034 14.2 0.1 0.081 13.0 0.1 1.6 1 0 0 1 1 1 0 Tenuivirus movement protein Pkinase PF00069.25 AIN96201.1 - 2.3e-41 141.9 0.0 1.6e-26 93.3 0.0 2.7 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 AIN96201.1 - 4.4e-16 58.9 0.4 7.6e-09 35.2 0.2 3.1 2 1 0 2 2 2 2 Protein tyrosine kinase RWD PF05773.22 AIN96201.1 - 1e-05 25.8 0.2 5e-05 23.6 0.0 2.1 2 0 0 2 2 2 1 RWD domain APH PF01636.23 AIN96201.1 - 0.0028 17.6 0.0 0.0094 15.9 0.0 1.8 2 0 0 2 2 2 1 Phosphotransferase enzyme family FTA2 PF13095.6 AIN96201.1 - 0.0089 15.7 0.1 0.37 10.4 0.0 2.3 2 0 0 2 2 2 1 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.14 AIN96201.1 - 0.022 14.1 0.0 0.051 12.9 0.0 1.6 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family NCD1 PF04904.13 AIN96201.1 - 0.038 14.0 0.1 0.42 10.7 0.0 2.4 2 0 0 2 2 2 0 NAB conserved region 1 (NCD1) PI3K_1B_p101 PF10486.9 AIN96201.1 - 3.7 5.2 12.0 5.7 4.6 12.0 1.2 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Spc7 PF08317.11 AIN96202.1 - 0.005 15.8 16.7 0.005 15.8 16.7 3.3 1 1 1 3 3 3 2 Spc7 kinetochore protein FAM76 PF16046.5 AIN96202.1 - 0.01 15.2 5.1 0.01 15.2 5.1 3.2 1 1 2 3 3 3 0 FAM76 protein DUF3859 PF12975.7 AIN96202.1 - 0.083 12.9 0.2 0.49 10.4 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3859) EzrA PF06160.12 AIN96202.1 - 0.083 11.1 38.3 0.18 10.0 16.3 2.3 1 1 1 2 2 2 0 Septation ring formation regulator, EzrA DUF2746 PF10874.8 AIN96202.1 - 0.21 12.0 1.1 0.45 11.0 0.2 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF2746) Pox_A_type_inc PF04508.12 AIN96202.1 - 4.1 7.4 7.2 2.2 8.3 0.2 4.0 5 0 0 5 5 5 0 Viral A-type inclusion protein repeat GAS PF13851.6 AIN96202.1 - 4.6 6.5 45.2 17 4.7 32.6 3.2 1 1 0 2 2 2 0 Growth-arrest specific micro-tubule binding Filament PF00038.21 AIN96202.1 - 6.5 6.2 44.4 0.067 12.8 9.4 3.6 1 1 2 3 3 3 0 Intermediate filament protein Baculo_PEP_C PF04513.12 AIN96202.1 - 7.1 6.7 30.9 0.042 13.9 6.3 3.8 1 1 3 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF5082 PF16888.5 AIN96202.1 - 7.5 6.9 33.5 0.29 11.4 3.3 4.5 1 1 2 4 4 4 0 Domain of unknown function (DUF5082) GRIP PF01465.20 AIN96203.1 - 2.4e-11 43.3 0.0 4.6e-11 42.4 0.0 1.5 1 0 0 1 1 1 1 GRIP domain Atg14 PF10186.9 AIN96203.1 - 0.0014 17.8 5.3 0.0014 17.8 5.3 1.8 2 0 0 2 2 2 1 Vacuolar sorting 38 and autophagy-related subunit 14 Fzo_mitofusin PF04799.13 AIN96203.1 - 0.0074 15.8 3.4 0.0074 15.8 3.4 1.9 2 0 0 2 2 2 1 fzo-like conserved region APG6_N PF17675.1 AIN96203.1 - 0.008 16.7 13.5 0.021 15.4 9.1 2.5 2 0 0 2 2 2 1 Apg6 coiled-coil region DUF5327 PF17261.2 AIN96203.1 - 0.11 13.3 7.3 0.12 13.1 3.6 2.5 2 0 0 2 2 2 0 Family of unknown function (DUF5327) Jnk-SapK_ap_N PF09744.9 AIN96203.1 - 0.14 12.3 12.0 0.14 12.4 8.4 2.3 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 Cnn_1N PF07989.11 AIN96203.1 - 0.54 10.5 13.9 2.4 8.4 7.0 3.4 2 2 0 2 2 2 0 Centrosomin N-terminal motif 1 YabA PF06156.13 AIN96203.1 - 0.57 10.8 8.6 4.7 7.9 0.1 2.8 2 1 0 2 2 2 0 Initiation control protein YabA BRE1 PF08647.11 AIN96203.1 - 0.85 9.7 9.9 4.7 7.3 4.5 2.6 2 0 0 2 2 2 0 BRE1 E3 ubiquitin ligase THOC7 PF05615.13 AIN96203.1 - 1.2 9.4 12.0 0.063 13.6 6.1 1.9 2 0 0 2 2 2 0 Tho complex subunit 7 Syntaxin-6_N PF09177.11 AIN96203.1 - 1.4 9.5 9.3 4.7 7.8 7.3 2.6 2 0 0 2 2 2 0 Syntaxin 6, N-terminal TMF_TATA_bd PF12325.8 AIN96203.1 - 1.8 8.8 14.7 0.62 10.3 9.8 2.5 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding Tho2 PF11262.8 AIN96203.1 - 1.9 7.7 7.0 0.72 9.0 2.1 2.5 3 0 0 3 3 3 0 Transcription factor/nuclear export subunit protein 2 DUF1192 PF06698.11 AIN96203.1 - 2.6 8.2 10.7 26 4.9 3.9 3.7 3 1 0 3 3 3 0 Protein of unknown function (DUF1192) Seryl_tRNA_N PF02403.22 AIN96203.1 - 7.4 6.9 13.1 2.5 8.4 7.0 2.6 3 0 0 3 3 3 0 Seryl-tRNA synthetase N-terminal domain RRM_1 PF00076.22 AIN96204.1 - 8.2e-05 22.3 0.0 0.00018 21.3 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) ATP19 PF11022.8 AIN96204.1 - 0.14 12.6 0.0 0.33 11.4 0.0 1.7 1 0 0 1 1 1 0 ATP synthase subunit K PHM7_cyt PF14703.6 AIN96204.1 - 0.39 10.9 6.1 0.16 12.2 0.6 2.0 1 1 0 2 2 2 0 Cytosolic domain of 10TM putative phosphate transporter MORN PF02493.20 AIN96205.1 - 6.8e-25 85.4 31.6 1.4e-06 27.9 0.4 6.6 7 0 0 7 7 7 6 MORN repeat tRNA-synt_2b PF00587.25 AIN96206.1 - 3.9e-32 111.6 0.0 7.2e-32 110.8 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.22 AIN96206.1 - 4.3e-14 52.7 3.5 1.3e-12 47.9 3.5 2.3 1 1 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain Pkinase PF00069.25 AIN96207.1 - 1.6e-49 168.6 0.0 2.1e-49 168.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 AIN96207.1 - 7.6e-26 90.9 0.0 1.1e-25 90.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 AIN96207.1 - 2.6e-09 36.8 0.0 5.8e-09 35.7 0.0 1.5 1 1 1 2 2 2 1 Kinase-like APH PF01636.23 AIN96207.1 - 0.0002 21.3 0.4 0.00093 19.2 0.2 2.0 1 1 1 2 2 2 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 AIN96207.1 - 0.0015 17.6 0.0 0.0024 16.9 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Seadorna_VP7 PF07387.11 AIN96207.1 - 0.0016 17.6 0.1 0.0024 17.0 0.1 1.1 1 0 0 1 1 1 1 Seadornavirus VP7 Kdo PF06293.14 AIN96207.1 - 0.0017 17.8 0.1 0.0034 16.8 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family PAC1 PF16094.5 AIN96207.1 - 0.025 13.8 0.0 0.037 13.2 0.0 1.1 1 0 0 1 1 1 0 Proteasome assembly chaperone 4 Choline_kinase PF01633.20 AIN96207.1 - 0.22 11.0 0.0 0.34 10.5 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase Foamy_virus_ENV PF03408.14 AIN96208.1 - 0.014 13.3 0.1 0.016 13.1 0.1 1.0 1 0 0 1 1 1 0 Foamy virus envelope protein NIF3 PF01784.18 AIN96209.1 - 9.8e-68 228.4 0.0 1.2e-67 228.1 0.0 1.0 1 0 0 1 1 1 1 NIF3 (NGG1p interacting factor 3) PSP1 PF04468.12 AIN96210.1 - 5.5e-28 97.1 0.2 9e-28 96.4 0.2 1.3 1 0 0 1 1 1 1 PSP1 C-terminal conserved region Macoilin PF09726.9 AIN96211.1 - 2.8 6.4 28.4 0.13 10.8 22.7 1.6 2 0 0 2 2 2 0 Macoilin family 3-PAP PF12578.8 AIN96213.1 - 1.7e-14 53.7 2.1 1.7e-14 53.7 2.1 1.9 2 0 0 2 2 2 1 Myotubularin-associated protein Dzip-like_N PF13815.6 AIN96213.1 - 9.6e-06 25.6 1.4 9.6e-06 25.6 1.4 3.1 2 1 1 3 3 3 1 Iguana/Dzip1-like DAZ-interacting protein N-terminal IFT57 PF10498.9 AIN96213.1 - 1.8 7.5 10.9 0.21 10.5 5.7 1.8 2 0 0 2 2 2 0 Intra-flagellar transport protein 57 SKA1 PF07160.12 AIN96213.1 - 6.3 6.6 13.3 1.5 8.6 3.3 3.2 2 1 1 3 3 3 0 Spindle and kinetochore-associated protein 1 Laminin_II PF06009.12 AIN96213.1 - 6.6 6.7 12.3 1.4 9.0 5.9 2.3 2 0 0 2 2 2 0 Laminin Domain II HAUS-augmin3 PF14932.6 AIN96213.1 - 8.6 5.8 20.0 0.36 10.4 12.2 2.3 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 3 Pre-PUA PF17832.1 AIN96214.1 - 4e-19 69.1 0.2 6e-19 68.5 0.2 1.2 1 0 0 1 1 1 1 Pre-PUA-like domain PUA PF01472.20 AIN96214.1 - 5.4e-13 48.7 1.6 9.9e-13 47.9 1.6 1.4 1 0 0 1 1 1 1 PUA domain DUF1947 PF09183.10 AIN96214.1 - 0.0097 16.2 0.6 0.26 11.6 0.2 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF1947) PBSX_XtrA PF17356.2 AIN96214.1 - 0.095 12.6 0.4 15 5.6 0.1 2.3 2 0 0 2 2 2 0 Phage-like element PBSX protein XtrA FumaraseC_C PF10415.9 AIN96214.1 - 0.13 12.7 0.2 0.22 12.0 0.2 1.3 1 0 0 1 1 1 0 Fumarase C C-terminus DEAD PF00270.29 AIN96215.1 - 4.3e-23 82.0 0.0 6.8e-23 81.3 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 AIN96215.1 - 2.4e-07 30.9 0.0 5.4e-07 29.8 0.0 1.6 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 AIN96215.1 - 6.5e-06 26.5 0.1 2e-05 24.9 0.1 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain Pyrophosphatase PF00719.19 AIN96217.1 - 4.3e-45 153.4 0.0 8.4e-45 152.4 0.0 1.5 1 0 0 1 1 1 1 Inorganic pyrophosphatase EF-hand_7 PF13499.6 AIN96217.1 - 0.00013 22.3 0.0 0.00058 20.3 0.0 2.1 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_9 PF14658.6 AIN96217.1 - 0.085 13.2 0.0 0.2 12.0 0.0 1.6 1 0 0 1 1 1 0 EF-hand domain Pterin_4a PF01329.19 AIN96218.1 - 2.5e-28 98.1 0.0 2.8e-28 97.9 0.0 1.0 1 0 0 1 1 1 1 Pterin 4 alpha carbinolamine dehydratase Rad51 PF08423.11 AIN96219.1 - 7e-19 68.1 0.0 1.6e-18 66.9 0.0 1.6 1 1 0 1 1 1 1 Rad51 AAA_25 PF13481.6 AIN96219.1 - 3e-07 30.2 0.4 1.1e-06 28.4 0.4 1.9 1 1 0 1 1 1 1 AAA domain ATPase PF06745.13 AIN96219.1 - 7.1e-07 28.8 0.0 8.4e-06 25.3 0.0 2.0 2 0 0 2 2 2 1 KaiC DnaB_C PF03796.15 AIN96219.1 - 1.6e-06 27.6 0.0 0.043 13.2 0.0 2.1 2 0 0 2 2 2 2 DnaB-like helicase C terminal domain AAA PF00004.29 AIN96219.1 - 0.0002 21.8 0.0 0.00091 19.7 0.0 1.8 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RecA PF00154.21 AIN96219.1 - 0.0041 16.6 0.0 0.015 14.8 0.0 1.8 2 0 0 2 2 2 1 recA bacterial DNA recombination protein AAA_33 PF13671.6 AIN96219.1 - 0.019 15.1 0.2 0.034 14.3 0.2 1.6 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.6 AIN96219.1 - 0.023 15.1 0.2 0.088 13.2 0.1 1.9 2 0 0 2 2 2 0 AAA ATPase domain AAA_22 PF13401.6 AIN96219.1 - 0.11 12.7 0.8 0.49 10.7 0.8 1.9 1 1 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 AIN96219.1 - 0.12 12.2 0.0 0.22 11.4 0.0 1.4 1 0 0 1 1 1 0 NTPase AAA_18 PF13238.6 AIN96219.1 - 0.12 12.9 0.0 0.39 11.3 0.1 1.8 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 AIN96219.1 - 0.13 12.0 0.0 0.24 11.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain Proteasome PF00227.26 AIN96220.1 - 3e-57 193.2 0.1 4e-57 192.8 0.1 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 AIN96220.1 - 1.6e-14 53.3 0.2 2.7e-14 52.5 0.2 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Styelin PF17562.2 AIN96220.1 - 0.055 13.8 5.1 0.16 12.4 2.8 2.3 2 0 0 2 2 2 0 Styelin Pkinase PF00069.25 AIN96221.1 - 1.9e-44 152.0 0.0 8.7e-32 110.5 0.0 3.2 3 0 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.17 AIN96221.1 - 2.9e-27 95.6 0.0 9.8e-21 74.2 0.0 3.2 3 0 0 3 3 3 3 Protein tyrosine kinase Pkinase_fungal PF17667.1 AIN96221.1 - 0.00014 20.8 0.0 0.0003 19.7 0.0 1.6 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 AIN96221.1 - 0.0014 18.0 0.0 0.25 10.6 0.0 2.2 2 0 0 2 2 2 2 Kinase-like PEPCK_ATP PF01293.20 AIN96222.1 - 0.18 10.4 0.0 0.27 9.9 0.0 1.1 1 0 0 1 1 1 0 Phosphoenolpyruvate carboxykinase FAD_binding_6 PF00970.24 AIN96223.1 - 3.9e-09 36.8 0.0 1.7e-08 34.7 0.0 1.9 2 0 0 2 2 2 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.21 AIN96223.1 - 0.078 13.6 0.0 0.17 12.6 0.0 1.6 2 0 0 2 2 2 0 Oxidoreductase NAD-binding domain Sec20 PF03908.13 AIN96226.1 - 2.9e-10 39.9 4.0 5.3e-10 39.1 3.4 1.7 2 0 0 2 2 2 1 Sec20 DHR10 PF18595.1 AIN96226.1 - 0.076 13.1 0.7 0.076 13.1 0.7 3.1 3 1 0 3 3 3 0 Designed helical repeat protein 10 domain DASH_Duo1 PF08651.10 AIN96226.1 - 0.092 12.5 0.2 0.23 11.2 0.2 1.6 1 0 0 1 1 1 0 DASH complex subunit Duo1 FlaC_arch PF05377.11 AIN96226.1 - 0.17 12.3 0.6 0.69 10.3 0.7 2.0 1 1 1 2 2 2 0 Flagella accessory protein C (FlaC) TMEM247 PF15444.6 AIN96226.1 - 0.18 11.9 3.9 0.36 10.9 0.2 2.2 1 1 0 2 2 2 0 Transmembrane protein 247 TFIIF_alpha PF05793.12 AIN96226.1 - 0.6 8.6 2.4 0.72 8.4 2.4 1.0 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) PIF1 PF05970.14 AIN96228.1 - 3e-30 105.6 2.2 3.7e-23 82.3 1.0 3.7 3 1 0 3 3 3 3 PIF1-like helicase AAA_30 PF13604.6 AIN96228.1 - 1.2e-19 70.8 0.0 3.1e-19 69.4 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 AIN96228.1 - 2e-05 25.0 2.3 2.8e-05 24.5 0.2 2.3 2 1 0 2 2 2 1 AAA domain Herpes_Helicase PF02689.14 AIN96228.1 - 0.00025 19.2 0.2 0.44 8.4 0.1 2.6 3 0 0 3 3 3 2 Helicase DUF853 PF05872.12 AIN96228.1 - 0.0017 17.0 1.2 0.0034 16.0 1.2 1.4 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF853) AAA_22 PF13401.6 AIN96228.1 - 0.0021 18.4 1.6 1.9 8.8 0.0 2.9 2 0 0 2 2 2 2 AAA domain UvrD_C_2 PF13538.6 AIN96228.1 - 0.015 15.1 0.4 0.1 12.4 0.4 2.3 1 1 0 1 1 1 0 UvrD-like helicase C-terminal domain AAA_11 PF13086.6 AIN96228.1 - 0.073 12.8 4.7 3 7.6 0.1 3.5 2 1 1 3 3 3 0 AAA domain RsgA_GTPase PF03193.16 AIN96228.1 - 0.14 12.1 0.2 0.34 10.8 0.2 1.6 1 0 0 1 1 1 0 RsgA GTPase Viral_helicase1 PF01443.18 AIN96228.1 - 0.15 11.8 0.9 10 5.8 0.0 3.0 2 1 0 2 2 2 0 Viral (Superfamily 1) RNA helicase ABC_tran PF00005.27 AIN96228.1 - 1.6 9.2 3.4 0.88 10.1 0.4 2.1 2 0 0 2 2 2 0 ABC transporter PIF1 PF05970.14 AIN96229.1 - 4.2e-35 121.6 0.8 8e-28 97.6 0.1 3.4 2 1 1 3 3 3 3 PIF1-like helicase AAA_30 PF13604.6 AIN96229.1 - 5.9e-18 65.3 0.0 2.9e-17 63.0 0.0 2.2 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 AIN96229.1 - 6.7e-06 26.5 0.1 3.4e-05 24.2 0.1 2.3 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 AIN96229.1 - 0.0015 18.9 0.0 0.0086 16.5 0.0 2.4 1 0 0 1 1 1 1 AAA ATPase domain Viral_helicase1 PF01443.18 AIN96229.1 - 0.0018 18.1 0.3 1.7 8.3 0.1 3.1 2 1 0 2 2 2 2 Viral (Superfamily 1) RNA helicase Mg_chelatase PF01078.21 AIN96229.1 - 0.006 16.0 0.2 0.015 14.7 0.2 1.6 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_22 PF13401.6 AIN96229.1 - 0.0072 16.6 0.5 0.16 12.2 0.2 2.6 1 1 0 2 2 2 1 AAA domain AAA PF00004.29 AIN96229.1 - 0.0091 16.4 0.0 0.027 14.9 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_11 PF13086.6 AIN96229.1 - 0.012 15.4 1.5 0.068 12.9 0.0 2.7 2 1 0 3 3 3 0 AAA domain AAA_5 PF07728.14 AIN96229.1 - 0.03 14.3 0.0 0.1 12.6 0.0 1.9 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Herpes_Helicase PF02689.14 AIN96229.1 - 0.032 12.2 0.3 0.16 9.8 0.0 1.9 2 0 0 2 2 2 0 Helicase UvrD_C_2 PF13538.6 AIN96229.1 - 0.033 14.0 1.6 0.12 12.2 0.4 2.5 2 1 0 2 2 2 0 UvrD-like helicase C-terminal domain DinB_2 PF12867.7 AIN96229.1 - 0.074 13.6 0.7 0.97 10.0 0.1 3.1 4 0 0 4 4 3 0 DinB superfamily PhoH PF02562.16 AIN96229.1 - 0.082 12.3 0.0 0.29 10.6 0.0 1.9 1 0 0 1 1 1 0 PhoH-like protein Coilin_N PF15862.5 AIN96230.1 - 0.085 12.7 0.0 1.7 8.5 0.0 2.5 2 1 0 2 2 2 0 Coilin N-terminus 14-3-3 PF00244.20 AIN96231.1 - 1.9e-83 279.4 1.3 2.2e-83 279.2 1.3 1.0 1 0 0 1 1 1 1 14-3-3 protein RE_XcyI PF09571.10 AIN96231.1 - 0.09 12.0 0.0 0.13 11.5 0.0 1.2 1 0 0 1 1 1 0 XcyI restriction endonuclease OPA3 PF07047.12 AIN96232.1 - 2e-19 69.6 2.9 2.2e-18 66.2 2.9 2.2 1 1 0 1 1 1 1 Optic atrophy 3 protein (OPA3) DUF2779 PF11074.8 AIN96234.1 - 8e-37 126.5 0.0 1.4e-36 125.8 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function(DUF2779) DUF3450 PF11932.8 AIN96234.1 - 1.2 8.4 6.4 2.2 7.5 6.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) TTL PF03133.15 AIN96236.1 - 3.7e-67 226.5 0.0 5.9e-67 225.9 0.0 1.2 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 AIN96236.1 - 4e-08 32.8 0.1 0.00047 19.5 0.0 3.2 2 1 1 3 3 3 3 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 AIN96236.1 - 0.00025 20.4 0.0 0.079 12.2 0.0 2.5 2 1 0 2 2 2 2 Sugar-transfer associated ATP-grasp ATP-grasp_3 PF02655.14 AIN96236.1 - 0.044 13.8 0.0 0.11 12.6 0.0 1.6 1 0 0 1 1 1 0 ATP-grasp domain TipE PF16972.5 AIN96236.1 - 9.4 5.3 11.2 21 4.2 11.2 1.5 1 0 0 1 1 1 0 Na+ channel auxiliary subunit TipE BOP1NT PF08145.12 AIN96237.1 - 6.9e-78 262.2 7.6 1.1e-77 261.5 7.6 1.3 1 0 0 1 1 1 1 BOP1NT (NUC169) domain WD40 PF00400.32 AIN96237.1 - 7.9e-18 64.5 4.7 9e-08 32.7 0.0 5.7 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 AIN96237.1 - 1e-07 32.2 0.0 0.00079 19.7 0.0 4.5 3 1 1 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 AIN96237.1 - 0.024 13.6 0.0 0.88 8.5 0.0 2.6 3 0 0 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein RCC1 PF00415.18 AIN96238.1 - 4.8e-26 91.1 18.2 7.5e-07 29.7 0.0 8.1 7 2 0 7 7 7 4 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 AIN96238.1 - 4.5e-11 42.2 27.5 1e-06 28.3 0.5 6.5 7 0 0 7 7 7 3 Regulator of chromosome condensation (RCC1) repeat LRR_4 PF12799.7 AIN96240.1 - 1.8e-13 50.4 13.2 0.00013 22.2 0.3 4.0 3 1 1 4 4 4 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 AIN96240.1 - 2e-08 33.9 20.6 0.0005 19.8 4.2 4.1 2 1 2 4 4 4 4 Leucine rich repeat LRR_9 PF14580.6 AIN96240.1 - 0.0011 18.5 0.4 0.018 14.6 0.3 2.2 1 1 1 2 2 2 2 Leucine-rich repeat LRR_1 PF00560.33 AIN96240.1 - 0.015 15.7 15.4 11 7.1 0.1 6.3 5 1 0 5 5 5 0 Leucine Rich Repeat LRR_6 PF13516.6 AIN96240.1 - 0.068 13.3 19.9 0.2 11.8 0.8 4.8 6 0 0 6 6 6 0 Leucine Rich repeat DNA_ligase_A_M PF01068.21 AIN96241.1 - 0.029 14.0 0.0 6.3 6.4 0.0 3.2 4 0 0 4 4 4 0 ATP dependent DNA ligase domain DNA_ligase_OB_2 PF14743.6 AIN96241.1 - 0.058 13.4 0.0 0.15 12.1 0.0 1.7 1 0 0 1 1 1 0 DNA ligase OB-like domain PUF PF00806.19 AIN96243.1 - 2.6e-10 39.4 0.0 0.042 13.5 0.0 5.9 5 0 0 5 5 5 3 Pumilio-family RNA binding repeat CPL PF08144.11 AIN96243.1 - 0.0058 17.0 4.5 0.093 13.1 0.1 4.4 3 2 1 4 4 4 1 CPL (NUC119) domain Pox_MCEL PF03291.16 AIN96245.1 - 9.3e-15 54.6 0.0 1.5e-14 53.9 0.0 1.2 1 0 0 1 1 1 1 mRNA capping enzyme Methyltransf_25 PF13649.6 AIN96245.1 - 4.8e-08 33.6 0.0 2.7e-07 31.2 0.0 2.4 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_11 PF08241.12 AIN96245.1 - 1.2e-05 25.8 0.0 6e-05 23.6 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 AIN96245.1 - 0.00014 22.6 0.0 0.00037 21.2 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 AIN96245.1 - 0.00067 19.5 0.0 0.0014 18.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain NSP16 PF06460.12 AIN96245.1 - 0.012 14.7 0.1 0.02 14.0 0.1 1.2 1 0 0 1 1 1 0 Coronavirus NSP16 PHF5 PF03660.14 AIN96245.1 - 0.088 13.0 2.6 0.14 12.3 1.3 2.0 2 0 0 2 2 2 0 PHF5-like protein zf-CHY PF05495.12 AIN96245.1 - 0.4 11.2 6.3 0.99 9.9 6.3 1.6 1 0 0 1 1 1 0 CHY zinc finger CEBP_ZZ PF16366.5 AIN96245.1 - 5.2 7.4 9.5 37 4.6 4.7 3.0 2 0 0 2 2 2 0 Cytoplasmic polyadenylation element-binding protein ZZ domain TPR_1 PF00515.28 AIN96246.1 - 4e-18 64.4 7.3 0.00018 21.2 0.3 6.1 7 0 0 7 7 6 4 Tetratricopeptide repeat TPR_2 PF07719.17 AIN96246.1 - 1.1e-17 62.7 5.9 0.0002 21.2 0.6 6.8 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_11 PF13414.6 AIN96246.1 - 3.1e-15 55.6 0.4 0.00025 20.7 0.0 4.5 3 1 1 4 4 4 3 TPR repeat TPR_12 PF13424.6 AIN96246.1 - 7e-11 42.3 7.0 0.0011 19.2 0.1 5.6 5 1 1 6 6 6 2 Tetratricopeptide repeat TPR_16 PF13432.6 AIN96246.1 - 1.2e-09 38.6 2.2 0.0039 17.8 0.1 5.6 3 2 3 6 6 6 2 Tetratricopeptide repeat TPR_8 PF13181.6 AIN96246.1 - 5.9e-09 35.4 8.2 0.0084 16.3 0.5 6.9 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_19 PF14559.6 AIN96246.1 - 1.6e-08 34.9 1.3 0.1 13.1 0.0 4.6 4 1 0 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.6 AIN96246.1 - 6.9e-07 28.9 0.0 0.017 15.1 0.0 4.0 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_17 PF13431.6 AIN96246.1 - 1.4e-06 28.2 7.9 0.25 11.8 0.0 5.6 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_14 PF13428.6 AIN96246.1 - 2.1e-05 24.9 2.9 2.3 9.3 0.0 4.8 2 2 2 4 4 4 2 Tetratricopeptide repeat DUF3808 PF10300.9 AIN96246.1 - 0.00035 19.4 0.3 0.0019 17.1 0.1 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF3808) TPR_MalT PF17874.1 AIN96246.1 - 0.0014 18.0 0.2 0.32 10.3 0.0 3.1 3 1 0 3 3 3 1 MalT-like TPR region TPR_6 PF13174.6 AIN96246.1 - 0.0042 17.6 6.8 1.5 9.6 0.0 5.2 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_10 PF13374.6 AIN96246.1 - 0.0092 15.8 2.4 0.12 12.3 0.0 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat HYLS1_C PF15311.6 AIN96246.1 - 0.077 13.8 0.0 0.19 12.5 0.0 1.6 1 0 0 1 1 1 0 Hydrolethalus syndrome protein 1 C-terminus ANAPC3 PF12895.7 AIN96246.1 - 0.11 12.8 3.3 6.9 7.0 0.1 3.2 3 0 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 Sel1 PF08238.12 AIN96246.1 - 0.13 13.0 0.8 16 6.3 0.8 3.3 2 1 0 2 2 2 0 Sel1 repeat MIT PF04212.18 AIN96246.1 - 1.7 8.7 12.5 5.1 7.3 0.1 4.4 5 0 0 5 5 5 0 MIT (microtubule interacting and transport) domain Pkinase PF00069.25 AIN96249.1 - 2.3e-31 109.1 0.0 4.9e-31 108.1 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 AIN96249.1 - 8.6e-14 51.4 0.0 6.1e-12 45.4 0.0 2.6 2 1 0 2 2 2 1 Protein tyrosine kinase RIO1 PF01163.22 AIN96249.1 - 0.00049 19.8 0.0 0.00097 18.8 0.0 1.4 1 0 0 1 1 1 1 RIO1 family Pox_ser-thr_kin PF05445.11 AIN96249.1 - 0.0014 17.7 0.0 0.0021 17.1 0.0 1.2 1 0 0 1 1 1 1 Poxvirus serine/threonine protein kinase Pkinase_fungal PF17667.1 AIN96249.1 - 0.0065 15.3 0.0 0.0079 15.0 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 AIN96249.1 - 0.12 11.7 0.1 0.4 9.9 0.0 1.8 2 0 0 2 2 2 0 Kinase-like Choline_kinase PF01633.20 AIN96249.1 - 0.18 11.3 0.1 0.39 10.3 0.1 1.5 1 0 0 1 1 1 0 Choline/ethanolamine kinase AA_permease_2 PF13520.6 AIN96250.1 - 4.3e-19 68.6 38.2 4.3e-19 68.6 38.2 1.4 1 1 0 1 1 1 1 Amino acid permease DUF563 PF04577.14 AIN96252.1 - 4.1e-12 46.7 0.2 1.8e-11 44.6 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF563) Nucleoside_tran PF01733.18 AIN96253.1 - 4.8e-34 118.1 11.7 5.5e-25 88.4 0.0 2.7 2 1 1 3 3 3 2 Nucleoside transporter Tex_N PF09371.10 AIN96254.1 - 1.2e-37 129.4 0.0 2.5e-37 128.3 0.0 1.6 1 0 0 1 1 1 1 Tex-like protein N-terminal domain Tex_YqgF PF16921.5 AIN96254.1 - 1e-32 113.3 0.1 2.6e-32 111.9 0.1 1.7 1 0 0 1 1 1 1 Tex protein YqgF-like domain HHH_9 PF17674.1 AIN96254.1 - 2.2e-11 44.5 0.8 2.2e-09 38.1 0.3 3.4 2 1 0 2 2 2 1 HHH domain HHH_3 PF12836.7 AIN96254.1 - 2e-09 37.5 0.0 4.5e-09 36.4 0.0 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix motif YqgF PF14639.6 AIN96254.1 - 1.1e-06 28.5 0.0 2.8e-06 27.2 0.0 1.7 1 0 0 1 1 1 1 Holliday-junction resolvase-like of SPT6 HHH_7 PF14635.6 AIN96254.1 - 0.0031 17.8 0.0 0.0066 16.8 0.0 1.5 1 0 0 1 1 1 1 Helix-hairpin-helix motif S1 PF00575.23 AIN96254.1 - 0.049 14.0 0.0 0.12 12.8 0.0 1.6 1 0 0 1 1 1 0 S1 RNA binding domain ArgoL2 PF16488.5 AIN96255.1 - 2.6e-10 40.5 0.2 6.8e-10 39.1 0.2 1.8 1 0 0 1 1 1 1 Argonaute linker 2 domain PAZ PF02170.22 AIN96255.1 - 1.3e-07 31.5 0.0 3e-07 30.3 0.0 1.5 1 0 0 1 1 1 1 PAZ domain Piwi PF02171.17 AIN96255.1 - 2.3e-06 27.1 0.1 2e-05 24.0 0.1 2.1 1 1 0 1 1 1 1 Piwi domain ArgoN PF16486.5 AIN96255.1 - 0.00022 21.8 0.0 0.00051 20.7 0.0 1.6 1 0 0 1 1 1 1 N-terminal domain of argonaute MecA_N PF05223.11 AIN96255.1 - 0.15 12.3 0.0 0.63 10.3 0.0 2.0 1 0 0 1 1 1 0 NTF2-like N-terminal transpeptidase domain Cyt-b5 PF00173.28 AIN96256.1 - 8.6e-19 67.5 0.1 2e-18 66.3 0.0 1.5 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain Carboxyl_trans PF01039.22 AIN96257.1 - 1.2e-142 476.1 0.0 1.8e-142 475.5 0.0 1.2 1 0 0 1 1 1 1 Carboxyl transferase domain MdcE PF06833.11 AIN96257.1 - 2.1e-05 24.1 0.1 0.16 11.4 0.0 2.4 2 0 0 2 2 2 2 Malonate decarboxylase gamma subunit (MdcE) Pdase_M17_N2 PF18295.1 AIN96260.1 - 3.1e-27 95.3 3.0 3.1e-27 95.3 3.0 1.6 2 0 0 2 2 2 1 M17 aminopeptidase N-terminal domain 2 Ribosomal_S11 PF00411.19 AIN96260.1 - 0.025 15.0 1.2 0.047 14.1 1.2 1.5 1 0 0 1 1 1 0 Ribosomal protein S11 ESX-1_EspG PF14011.6 AIN96260.1 - 0.067 12.8 8.5 0.18 11.4 8.7 1.6 1 1 1 2 2 2 0 EspG family Peptidase_M17 PF00883.21 AIN96261.1 - 4.4e-88 295.5 0.7 6.1e-88 295.1 0.7 1.2 1 0 0 1 1 1 1 Cytosol aminopeptidase family, catalytic domain Pdase_M17_N2 PF18295.1 AIN96261.1 - 2.5e-30 105.2 3.8 3.1e-30 105.0 1.4 2.4 3 0 0 3 3 3 1 M17 aminopeptidase N-terminal domain 2 ESX-1_EspG PF14011.6 AIN96261.1 - 0.011 15.3 3.6 0.02 14.5 3.6 1.5 1 0 0 1 1 1 0 EspG family 30K_MP_C_Ter PF11330.8 AIN96261.1 - 0.055 12.8 0.0 0.094 12.0 0.0 1.3 1 0 0 1 1 1 0 C-Terminal of 30K viral movement proteins MFS_1 PF07690.16 AIN96263.1 - 6.9e-22 77.8 36.2 1.9e-18 66.6 21.3 2.2 2 0 0 2 2 2 2 Major Facilitator Superfamily Nodulin-like PF06813.13 AIN96263.1 - 1.4e-09 37.8 11.8 7.3e-09 35.5 11.8 2.2 1 1 0 1 1 1 1 Nodulin-like Nodulin-like PF06813.13 AIN96264.1 - 5.5e-08 32.6 13.3 5.5e-08 32.6 13.3 2.8 2 1 0 2 2 2 1 Nodulin-like MotA_ExbB PF01618.16 AIN96264.1 - 0.28 11.0 0.9 0.9 9.3 0.0 2.3 2 0 0 2 2 2 0 MotA/TolQ/ExbB proton channel family PMP1_2 PF08114.11 AIN96264.1 - 3.6 7.4 7.3 7.5 6.4 0.1 4.0 4 0 0 4 4 4 0 ATPase proteolipid family Nodulin-like PF06813.13 AIN96265.1 - 6.2e-08 32.4 25.9 6.4e-08 32.4 17.6 3.3 2 1 1 3 3 3 1 Nodulin-like DUF4239 PF14023.6 AIN96265.1 - 0.031 14.0 0.1 0.087 12.5 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF4239) DUF3671 PF12420.8 AIN96265.1 - 0.16 12.1 4.7 6.5 6.9 0.0 3.8 3 1 1 4 4 4 0 Protein of unknown function E1-E2_ATPase PF00122.20 AIN96265.1 - 6.5 6.2 8.7 7 6.1 0.7 3.1 3 0 0 3 3 3 0 E1-E2 ATPase Ank_4 PF13637.6 AIN96266.1 - 2e-23 82.4 0.8 1e-06 29.1 0.0 4.4 2 2 2 4 4 4 4 Ankyrin repeats (many copies) Ank_2 PF12796.7 AIN96266.1 - 7.2e-22 77.8 0.6 2.9e-10 40.6 0.0 3.1 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 AIN96266.1 - 9.4e-17 60.9 2.6 0.00013 22.2 0.0 4.0 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.30 AIN96266.1 - 2.1e-15 56.4 0.6 0.00063 20.1 0.0 4.9 5 0 0 5 5 5 4 Ankyrin repeat Ank_3 PF13606.6 AIN96266.1 - 1.1e-14 53.1 0.4 0.002 18.5 0.0 5.3 5 0 0 5 5 5 3 Ankyrin repeat DpaA_N PF16924.5 AIN96266.1 - 0.016 15.3 0.6 0.41 10.7 0.1 2.8 3 1 1 4 4 4 0 Dipicolinate synthase subunit A N-terminal domain Ad_Cy_reg PF16701.5 AIN96266.1 - 0.036 13.8 0.1 0.2 11.4 0.0 2.0 1 1 1 2 2 2 0 Adenylate cyclase regulatory domain Amidinotransf PF02274.17 AIN96266.1 - 0.067 12.3 0.3 7.6 5.5 0.0 2.7 2 1 0 3 3 3 0 Amidinotransferase ArsA_ATPase PF02374.15 AIN96267.1 - 2.1e-88 296.4 0.0 6.9e-49 166.7 0.0 2.2 2 0 0 2 2 2 2 Anion-transporting ATPase AAA_31 PF13614.6 AIN96267.1 - 9.6e-08 32.1 0.0 5.9e-07 29.6 0.0 2.2 1 1 0 1 1 1 1 AAA domain CbiA PF01656.23 AIN96267.1 - 5.2e-07 29.8 0.0 4e-06 26.9 0.0 2.2 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain ParA PF10609.9 AIN96267.1 - 0.0082 15.6 0.1 0.029 13.8 0.1 1.8 2 0 0 2 2 2 1 NUBPL iron-transfer P-loop NTPase SRP54 PF00448.22 AIN96267.1 - 0.0093 15.6 0.1 2.2 7.9 0.1 2.4 2 0 0 2 2 2 2 SRP54-type protein, GTPase domain AAA_25 PF13481.6 AIN96267.1 - 0.02 14.5 0.0 0.044 13.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain Fer4_NifH PF00142.18 AIN96267.1 - 0.035 13.5 0.0 0.64 9.4 0.0 2.2 2 0 0 2 2 2 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family NB-ARC PF00931.22 AIN96267.1 - 0.1 11.8 0.1 0.19 10.9 0.1 1.4 1 0 0 1 1 1 0 NB-ARC domain VEK-30 PF12107.8 AIN96268.1 - 0.0065 16.3 2.7 0.12 12.3 2.5 2.9 2 0 0 2 2 2 1 Plasminogen (Pg) ligand in fibrinolytic pathway Peptidase_C11 PF03415.14 AIN96269.1 - 3.6e-07 29.9 0.0 5e-07 29.5 0.0 1.2 1 0 0 1 1 1 1 Clostripain family MIT PF04212.18 AIN96272.1 - 0.34 11.0 1.6 1.5 9.0 1.6 2.0 1 1 0 1 1 1 0 MIT (microtubule interacting and transport) domain Ribosomal_S21e PF01249.18 AIN96273.1 - 3e-33 113.8 0.2 3.8e-33 113.4 0.2 1.2 1 0 0 1 1 1 1 Ribosomal protein S21e Ribosomal_S21e PF01249.18 AIN96274.1 - 3.7e-33 113.5 0.2 4.9e-33 113.1 0.2 1.2 1 0 0 1 1 1 1 Ribosomal protein S21e Amelotin PF15757.5 AIN96274.1 - 1.3 8.5 10.1 1.8 8.1 2.7 2.2 1 1 1 2 2 2 0 Amelotin COX6B PF02297.17 AIN96275.1 - 0.0001 22.5 9.9 0.024 14.9 1.8 2.8 1 1 1 2 2 2 2 Cytochrome oxidase c subunit VIb CX9C PF16860.5 AIN96275.1 - 1.4 9.0 9.1 7.7 6.6 0.1 3.3 3 1 0 3 3 3 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, Pet191_N PF10203.9 AIN96275.1 - 2.5 8.5 8.1 15 6.0 0.4 3.2 3 0 0 3 3 3 0 Cytochrome c oxidase assembly protein PET191 EF-hand_6 PF13405.6 AIN96277.1 - 5.1e-13 47.8 0.0 0.92 9.6 0.0 7.2 8 0 0 8 8 8 4 EF-hand domain EF-hand_7 PF13499.6 AIN96277.1 - 6.2e-09 36.2 0.0 1.6 9.2 0.0 6.1 6 0 0 6 6 6 3 EF-hand domain pair EF-hand_1 PF00036.32 AIN96277.1 - 0.00064 19.1 0.0 22 4.9 0.0 5.0 6 0 0 6 6 6 2 EF hand EF-hand_8 PF13833.6 AIN96277.1 - 0.04 13.8 0.0 67 3.4 0.0 5.0 6 0 0 6 6 6 0 EF-hand domain pair EF-hand_11 PF08976.11 AIN96277.1 - 0.055 14.3 0.0 38 5.2 0.0 4.5 5 0 0 5 5 5 0 EF-hand domain DUF3552 PF12072.8 AIN96278.1 - 0.00021 20.8 11.5 0.00032 20.2 11.5 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3552) Poty_PP PF08440.10 AIN96278.1 - 0.15 11.1 3.7 0.21 10.6 3.7 1.1 1 0 0 1 1 1 0 Potyviridae polyprotein Exonuc_VII_L PF02601.15 AIN96278.1 - 0.21 11.1 8.8 0.29 10.7 8.8 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit APG6_N PF17675.1 AIN96278.1 - 0.35 11.4 16.1 0.57 10.7 16.1 1.3 1 0 0 1 1 1 0 Apg6 coiled-coil region Jnk-SapK_ap_N PF09744.9 AIN96278.1 - 0.57 10.4 13.3 1 9.6 13.3 1.3 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 OmpH PF03938.14 AIN96278.1 - 4.1 7.7 22.8 7.8 6.8 22.8 1.4 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) V_ATPase_I PF01496.19 AIN96278.1 - 4.4 5.1 8.0 5.9 4.7 8.0 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family LRS4 PF10422.9 AIN96279.1 - 0.028 14.0 9.4 0.073 12.6 9.4 1.7 1 0 0 1 1 1 0 Monopolin complex subunit LRS4 AAA_13 PF13166.6 AIN96279.1 - 0.28 9.8 9.5 0.42 9.2 9.5 1.1 1 0 0 1 1 1 0 AAA domain Spc7 PF08317.11 AIN96279.1 - 0.43 9.4 12.0 0.77 8.6 12.0 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein FapA PF03961.13 AIN96279.1 - 0.63 8.6 7.1 0.96 8.0 7.1 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A DUF2203 PF09969.9 AIN96279.1 - 1.1 10.0 6.0 3 8.6 6.0 1.8 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) TMF_DNA_bd PF12329.8 AIN96279.1 - 1.7 8.7 25.5 0.014 15.4 13.6 2.6 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding BshC PF10079.9 AIN96279.1 - 4.3 6.0 9.8 7.1 5.2 9.8 1.2 1 0 0 1 1 1 0 Bacillithiol biosynthesis BshC V_ATPase_I PF01496.19 AIN96279.1 - 9.2 4.0 5.7 15 3.4 5.7 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Abhydrolase_1 PF00561.20 AIN96280.1 - 7.3e-07 29.1 0.0 2.8e-06 27.2 0.0 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 AIN96280.1 - 3.1e-06 27.9 2.3 6.6e-06 26.9 2.3 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 AIN96280.1 - 0.0005 19.4 0.0 0.014 14.7 0.0 2.7 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Palm_thioest PF02089.15 AIN96280.1 - 0.13 12.1 0.0 0.17 11.7 0.0 1.2 1 0 0 1 1 1 0 Palmitoyl protein thioesterase HEAT PF02985.22 AIN96281.1 - 0.19 12.1 12.9 2.2 8.8 0.0 6.5 7 0 0 7 7 7 0 HEAT repeat ImpA_N PF06812.12 AIN96281.1 - 0.29 11.2 1.7 1.1 9.4 0.1 2.8 3 0 0 3 3 3 0 ImpA, N-terminal, type VI secretion system Kinesin PF00225.23 AIN96282.1 - 8.5e-88 294.5 0.0 1e-86 290.9 0.0 2.2 1 1 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 AIN96282.1 - 1.1e-21 77.3 0.0 2.4e-21 76.3 0.0 1.5 1 0 0 1 1 1 1 Microtubule binding KELK PF15796.5 AIN96282.1 - 4.9 7.7 11.5 0.24 11.9 3.7 2.5 2 0 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase START PF01852.19 AIN96283.1 - 2.3e-19 69.6 0.0 4.5e-19 68.7 0.0 1.4 1 0 0 1 1 1 1 START domain DUF3074 PF11274.8 AIN96283.1 - 0.04 13.9 0.1 0.34 10.9 0.1 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF3074) LRR_6 PF13516.6 AIN96284.1 - 1.3e-19 68.5 20.3 0.0035 17.3 0.1 11.6 11 0 0 11 11 11 7 Leucine Rich repeat LRR_4 PF12799.7 AIN96284.1 - 3.4e-08 33.6 20.4 0.37 11.3 0.0 8.8 7 1 4 11 11 11 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 AIN96284.1 - 5.4e-07 29.3 13.9 15 6.6 0.0 10.3 11 1 0 11 11 11 2 Leucine Rich Repeat LRR_8 PF13855.6 AIN96284.1 - 1.4e-06 28.0 25.9 0.059 13.2 4.1 7.9 8 2 0 8 8 8 4 Leucine rich repeat Ribosomal_L24e PF01246.20 AIN96285.1 - 1.1e-31 108.9 4.2 1.1e-31 108.9 4.2 2.5 2 0 0 2 2 2 1 Ribosomal protein L24e zf-FCS PF06467.14 AIN96285.1 - 0.19 11.7 6.4 0.36 10.8 6.4 1.4 1 0 0 1 1 1 0 MYM-type Zinc finger with FCS sequence motif AAA PF00004.29 AIN96286.1 - 3.1e-39 134.4 0.0 1.1e-38 132.6 0.0 2.1 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 AIN96286.1 - 9.9e-11 41.3 0.2 5.5e-10 38.9 0.0 2.3 2 0 0 2 2 2 1 AAA+ lid domain AAA_16 PF13191.6 AIN96286.1 - 9e-05 22.9 2.9 0.00031 21.2 1.2 2.8 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 AIN96286.1 - 0.00014 22.1 0.0 0.00041 20.6 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_2 PF07724.14 AIN96286.1 - 0.00016 21.8 0.0 0.00037 20.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 AIN96286.1 - 0.0042 17.1 0.1 0.042 13.9 0.1 2.5 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_33 PF13671.6 AIN96286.1 - 0.023 14.8 0.0 0.087 13.0 0.0 2.2 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 AIN96286.1 - 0.036 13.8 0.0 0.08 12.7 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_18 PF13238.6 AIN96286.1 - 0.047 14.2 0.1 0.2 12.2 0.0 2.2 2 0 0 2 2 1 0 AAA domain Mg_chelatase PF01078.21 AIN96286.1 - 0.052 12.9 0.1 0.12 11.8 0.1 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_28 PF13521.6 AIN96286.1 - 0.055 13.7 0.0 0.22 11.8 0.0 2.1 1 0 0 1 1 1 0 AAA domain RuvB_N PF05496.12 AIN96286.1 - 0.072 12.8 0.0 0.2 11.4 0.0 1.7 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_7 PF12775.7 AIN96286.1 - 0.084 12.4 0.0 0.16 11.5 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region GT-D PF08759.11 AIN96286.1 - 0.14 11.8 0.1 0.24 11.0 0.1 1.3 1 0 0 1 1 1 0 Glycosyltransferase GT-D fold PUB PF09409.10 AIN96287.1 - 6.7e-08 32.4 0.0 1.5e-07 31.2 0.0 1.5 1 0 0 1 1 1 1 PUB domain SHOCT PF09851.9 AIN96287.1 - 0.0076 15.9 0.2 0.0076 15.9 0.2 2.2 2 0 0 2 2 2 1 Short C-terminal domain hnRNP_Q_AcD PF18360.1 AIN96287.1 - 0.11 12.5 0.0 0.32 11.0 0.0 1.8 1 0 0 1 1 1 0 Heterogeneous nuclear ribonucleoprotein Q acidic domain BT1 PF03092.16 AIN96287.1 - 2.8 6.1 3.6 11 4.1 1.3 2.1 2 0 0 2 2 2 0 BT1 family Surp PF01805.20 AIN96288.1 - 0.0011 18.9 0.1 0.0033 17.4 0.1 1.7 1 0 0 1 1 1 1 Surp module SPT6_acidic PF14632.6 AIN96290.1 - 0.16 12.6 0.0 0.16 12.6 0.0 2.5 2 0 0 2 2 2 0 Acidic N-terminal SPT6 MSP1_C PF07462.11 AIN96290.1 - 1.1 7.9 3.1 6.7 5.3 2.1 2.0 2 0 0 2 2 2 0 Merozoite surface protein 1 (MSP1) C-terminus Ribosomal_S7 PF00177.21 AIN96291.1 - 3.2e-34 117.7 1.0 4e-34 117.4 1.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e Ribosomal_S7 PF00177.21 AIN96292.1 - 3.2e-34 117.7 1.0 4e-34 117.4 1.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e zf-HIT PF04438.16 AIN96293.1 - 5.8e-08 32.5 6.6 1.1e-07 31.5 6.6 1.5 1 0 0 1 1 1 1 HIT zinc finger zf-MYND PF01753.18 AIN96293.1 - 0.014 15.4 3.9 0.034 14.2 3.9 1.6 1 0 0 1 1 1 0 MYND finger Adaptin_N PF01602.20 AIN96294.1 - 5.4e-81 272.7 0.0 7.4e-81 272.3 0.0 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 AIN96294.1 - 1.5e-17 64.1 0.1 1.3e-16 61.0 0.0 2.8 5 0 0 5 5 5 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 AIN96294.1 - 8.9e-07 29.2 4.4 0.051 14.0 0.2 5.3 3 2 1 5 5 5 3 HEAT repeats HEAT_EZ PF13513.6 AIN96294.1 - 0.007 16.9 4.9 0.1 13.1 0.0 4.9 6 0 0 6 6 6 1 HEAT-like repeat Cnd3 PF12719.7 AIN96294.1 - 0.024 13.8 0.0 0.067 12.4 0.0 1.7 1 1 0 1 1 1 0 Nuclear condensing complex subunits, C-term domain HEAT PF02985.22 AIN96294.1 - 0.032 14.5 2.3 69 4.1 0.1 5.4 6 0 0 6 6 6 0 HEAT repeat DUF3137 PF11335.8 AIN96294.1 - 0.16 11.9 0.1 0.29 11.1 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3137) PEP-utilizers_C PF02896.18 AIN96295.1 - 1.6e-90 303.2 0.0 2.7e-90 302.5 0.0 1.3 1 0 0 1 1 1 1 PEP-utilising enzyme, TIM barrel domain PPDK_N PF01326.19 AIN96295.1 - 1.4e-75 254.6 0.0 2.4e-73 247.3 0.0 2.1 1 1 0 1 1 1 1 Pyruvate phosphate dikinase, PEP/pyruvate binding domain PEP-utilizers PF00391.23 AIN96295.1 - 4.8e-28 96.7 0.5 1.2e-27 95.4 0.5 1.7 1 0 0 1 1 1 1 PEP-utilising enzyme, mobile domain Sigma70_r4 PF04545.16 AIN96295.1 - 0.013 15.0 0.0 0.038 13.5 0.0 1.8 1 0 0 1 1 1 0 Sigma-70, region 4 DUF3788 PF12663.7 AIN96295.1 - 0.015 15.3 0.0 0.037 14.0 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3788) HTH_24 PF13412.6 AIN96295.1 - 0.037 13.6 0.0 0.091 12.3 0.0 1.6 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding HTH_AsnC-type PF13404.6 AIN96295.1 - 0.06 13.2 0.1 0.16 11.8 0.1 1.7 1 0 0 1 1 1 0 AsnC-type helix-turn-helix domain DUF968 PF06147.11 AIN96295.1 - 0.072 13.3 0.0 0.12 12.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF968) PEP-utilisers_N PF05524.13 AIN96295.1 - 0.095 12.9 0.2 5.3 7.2 0.1 2.9 2 0 0 2 2 2 0 PEP-utilising enzyme, N-terminal Exo_endo_phos PF03372.23 AIN96296.1 - 0.0021 17.6 0.0 0.0065 16.0 0.0 1.7 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Phage_HK97_TLTM PF06120.11 AIN96296.1 - 0.23 10.6 0.0 0.34 10.0 0.0 1.2 1 0 0 1 1 1 0 Tail length tape measure protein SAT PF16073.5 AIN96297.1 - 9e-08 32.1 0.2 5.8e-07 29.5 0.2 2.4 1 1 0 1 1 1 1 Starter unit:ACP transacylase in aflatoxin biosynthesis SecY PF00344.20 AIN96300.1 - 1e-62 212.2 8.7 1.3e-62 211.8 8.7 1.1 1 0 0 1 1 1 1 SecY translocase Plug_translocon PF10559.9 AIN96300.1 - 2.4e-13 49.6 0.0 5.7e-13 48.5 0.0 1.7 1 0 0 1 1 1 1 Plug domain of Sec61p TMEM237 PF15383.6 AIN96300.1 - 0.027 13.6 0.2 0.051 12.7 0.2 1.4 1 0 0 1 1 1 0 Transmembrane protein 237 DHHC PF01529.20 AIN96301.1 - 3.8e-27 95.0 12.5 3.8e-27 95.0 12.5 2.1 2 0 0 2 2 2 1 DHHC palmitoyltransferase DHHC PF01529.20 AIN96302.1 - 1.2e-22 80.5 19.1 1.2e-22 80.5 19.1 2.2 1 1 1 2 2 2 1 DHHC palmitoyltransferase EcsB PF05975.12 AIN96302.1 - 0.18 10.6 6.8 0.46 9.3 0.8 2.0 2 0 0 2 2 2 0 Bacterial ABC transporter protein EcsB p450 PF00067.22 AIN96303.1 - 3.4e-66 223.9 0.0 4.1e-66 223.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Ribosomal_L28e PF01778.17 AIN96305.1 - 1.7e-10 41.7 0.1 1.7e-10 41.7 0.1 1.5 2 0 0 2 2 2 1 Ribosomal L28e protein family WD40 PF00400.32 AIN96306.1 - 2.8e-08 34.3 11.7 0.084 13.8 0.2 5.5 5 0 0 5 5 5 3 WD domain, G-beta repeat Sec16_C PF12931.7 AIN96306.1 - 3e-06 27.1 0.0 2.9e-05 23.9 0.0 2.2 1 1 0 1 1 1 1 Sec23-binding domain of Sec16 TPR_12 PF13424.6 AIN96306.1 - 0.0073 16.6 1.6 0.31 11.3 0.1 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.28 AIN96306.1 - 0.017 14.9 1.1 0.54 10.2 0.9 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.17 AIN96306.1 - 0.023 14.8 6.5 0.49 10.6 0.8 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.6 AIN96306.1 - 0.17 12.0 1.6 2 8.6 0.6 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat GTP_EFTU PF00009.27 AIN96307.1 - 4.2e-41 140.6 0.0 7.7e-41 139.8 0.0 1.5 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 AIN96307.1 - 7.3e-29 100.3 0.1 2.3e-28 98.7 0.0 1.9 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 AIN96307.1 - 0.00023 21.5 0.5 0.0014 19.0 0.3 2.4 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 AIN96307.1 - 0.0011 19.0 0.0 0.0062 16.6 0.0 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase G-alpha PF00503.20 AIN96307.1 - 0.048 12.8 0.0 0.079 12.1 0.0 1.2 1 0 0 1 1 1 0 G-protein alpha subunit Mitofilin PF09731.9 AIN96307.1 - 0.46 9.3 11.7 0.7 8.7 11.7 1.2 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Ndc1_Nup PF09531.10 AIN96307.1 - 5.6 5.5 10.6 8.4 4.9 10.6 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup 60KD_IMP PF02096.20 AIN96308.1 - 2e-09 37.5 0.2 3.6e-09 36.7 0.2 1.3 1 0 0 1 1 1 1 60Kd inner membrane protein Ribosomal_S8 PF00410.19 AIN96309.1 - 5.4e-21 74.9 0.0 6.8e-21 74.5 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S8 Solute_trans_a PF03619.16 AIN96310.1 - 1.3e-74 251.1 16.1 1.6e-74 250.8 16.1 1.1 1 0 0 1 1 1 1 Organic solute transporter Ostalpha Prok-RING_2 PF14445.6 AIN96310.1 - 0.012 15.7 0.5 0.041 14.0 0.5 1.9 1 0 0 1 1 1 0 Prokaryotic RING finger family 2 Skp1 PF01466.19 AIN96311.1 - 1.3e-26 92.4 2.2 2.1e-26 91.7 2.2 1.3 1 0 0 1 1 1 1 Skp1 family, dimerisation domain Skp1_POZ PF03931.15 AIN96311.1 - 2.2e-12 47.0 0.0 1e-11 44.8 0.0 2.1 2 0 0 2 2 2 1 Skp1 family, tetramerisation domain ABC2_membrane_3 PF12698.7 AIN96312.1 - 1.8e-61 208.2 57.7 1e-39 136.7 24.8 3.3 3 1 0 3 3 3 2 ABC-2 family transporter protein ABC_tran PF00005.27 AIN96312.1 - 1.5e-54 184.2 0.0 3.7e-26 92.3 0.0 2.5 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 AIN96312.1 - 2.2e-16 60.5 0.4 4.2e-06 26.8 0.0 4.3 4 0 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system SRP54 PF00448.22 AIN96312.1 - 0.00024 20.8 0.1 0.69 9.5 0.0 2.3 2 0 0 2 2 2 2 SRP54-type protein, GTPase domain Zeta_toxin PF06414.12 AIN96312.1 - 0.0011 18.2 0.1 4.7 6.4 0.0 3.3 3 0 0 3 3 3 1 Zeta toxin AAA_23 PF13476.6 AIN96312.1 - 0.0027 18.2 9.9 0.36 11.3 0.0 3.2 3 0 0 3 3 3 2 AAA domain DUF4162 PF13732.6 AIN96312.1 - 0.003 18.3 0.0 1.1 10.1 0.0 2.6 2 0 0 2 2 2 1 Domain of unknown function (DUF4162) RsgA_GTPase PF03193.16 AIN96312.1 - 0.0033 17.4 0.1 0.33 10.8 0.0 2.4 2 0 0 2 2 2 1 RsgA GTPase SMC_N PF02463.19 AIN96312.1 - 0.0065 15.9 0.0 13 5.1 0.0 3.4 3 1 0 3 3 3 0 RecF/RecN/SMC N terminal domain SbcCD_C PF13558.6 AIN96312.1 - 0.0067 16.6 0.0 4.1 7.7 0.0 3.4 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_29 PF13555.6 AIN96312.1 - 0.0081 15.9 0.5 2 8.2 0.1 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_30 PF13604.6 AIN96312.1 - 0.0082 15.9 0.1 0.44 10.2 0.1 2.4 2 0 0 2 2 2 1 AAA domain AAA_15 PF13175.6 AIN96312.1 - 0.034 13.8 0.0 6.2 6.4 0.0 3.6 5 0 0 5 5 5 0 AAA ATPase domain MMR_HSR1 PF01926.23 AIN96312.1 - 0.11 12.6 0.1 18 5.4 0.0 3.0 3 0 0 3 3 3 0 50S ribosome-binding GTPase AAA PF00004.29 AIN96312.1 - 0.14 12.6 0.2 5.1 7.5 0.0 2.9 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) ABC2_membrane PF01061.24 AIN96312.1 - 0.36 10.2 55.6 0.12 11.7 14.5 5.0 4 1 0 4 4 4 0 ABC-2 type transporter DUF5074 PF16819.5 AIN96313.1 - 0.14 12.2 0.1 4.1 7.5 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF5074) ABC2_membrane_3 PF12698.7 AIN96315.1 - 2.6e-68 230.7 59.4 4e-48 164.3 15.6 2.8 3 0 0 3 3 3 2 ABC-2 family transporter protein ABC_tran PF00005.27 AIN96315.1 - 2.6e-51 173.7 0.0 1.2e-25 90.6 0.0 2.5 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 AIN96315.1 - 3.1e-17 63.3 0.1 3.1e-06 27.2 0.0 4.2 4 0 0 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 AIN96315.1 - 6.8e-06 26.0 0.0 1.6 8.3 0.0 4.1 4 0 0 4 4 4 1 AAA ATPase domain SMC_N PF02463.19 AIN96315.1 - 8.4e-06 25.4 0.1 0.58 9.6 0.0 3.3 3 0 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 AIN96315.1 - 8.3e-05 23.2 1.4 0.17 12.4 0.1 2.5 2 1 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 AIN96315.1 - 0.00043 20.2 0.1 0.062 13.2 0.0 2.4 2 0 0 2 2 2 1 RsgA GTPase SbcCD_C PF13558.6 AIN96315.1 - 0.00093 19.4 0.0 0.57 10.4 0.0 3.7 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_29 PF13555.6 AIN96315.1 - 0.0017 18.1 0.1 0.61 9.9 0.0 2.7 2 0 0 2 2 2 1 P-loop containing region of AAA domain SRP54 PF00448.22 AIN96315.1 - 0.0017 18.0 0.2 0.48 10.0 0.0 2.3 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain Zeta_toxin PF06414.12 AIN96315.1 - 0.0019 17.5 0.0 13 5.0 0.0 3.3 3 0 0 3 3 3 0 Zeta toxin DUF4162 PF13732.6 AIN96315.1 - 0.0028 18.3 0.0 4.6 8.0 0.0 2.7 2 0 0 2 2 2 2 Domain of unknown function (DUF4162) AAA_30 PF13604.6 AIN96315.1 - 0.013 15.2 0.0 1.1 9.0 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 AIN96315.1 - 0.039 14.3 0.0 2.1 8.7 0.0 2.5 2 0 0 2 2 2 0 AAA ATPase domain Arf PF00025.21 AIN96315.1 - 0.074 12.5 0.1 4.6 6.7 0.0 2.5 2 0 0 2 2 2 0 ADP-ribosylation factor family AAA PF00004.29 AIN96315.1 - 0.11 13.0 0.1 3.3 8.1 0.0 3.0 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 AIN96315.1 - 0.12 12.7 0.0 2.9 8.1 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 AIN96315.1 - 0.14 12.4 0.4 8.5 6.6 0.1 3.0 3 0 0 3 3 3 0 AAA domain cobW PF02492.19 AIN96315.1 - 0.15 11.6 0.5 4.9 6.7 0.0 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain DUF2172 PF09940.9 AIN96315.1 - 0.17 12.3 0.0 19 5.7 0.0 2.9 3 0 0 3 3 2 0 Domain of unknown function (DUF2172) AAA_19 PF13245.6 AIN96315.1 - 0.18 12.1 0.2 16 5.8 0.0 2.5 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 AIN96315.1 - 0.19 11.8 0.1 15 5.7 0.0 2.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase ABC2_membrane PF01061.24 AIN96315.1 - 0.2 11.1 53.4 0.0048 16.3 12.5 4.0 4 0 0 4 4 4 0 ABC-2 type transporter TatD_DNase PF01026.21 AIN96316.1 - 2.1e-44 151.8 0.0 2.9e-44 151.4 0.0 1.2 1 0 0 1 1 1 1 TatD related DNase Amidohydro_2 PF04909.14 AIN96316.1 - 0.002 18.0 0.0 0.48 10.2 0.0 2.4 2 0 0 2 2 2 2 Amidohydrolase ABC2_membrane_3 PF12698.7 AIN96317.1 - 1.4e-68 231.6 51.9 1.5e-46 159.1 18.5 2.3 2 0 0 2 2 2 2 ABC-2 family transporter protein ABC_tran PF00005.27 AIN96317.1 - 4.4e-50 169.7 0.0 7.4e-25 88.1 0.0 2.6 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 AIN96317.1 - 2.7e-16 60.2 2.9 1.9e-08 34.5 0.0 4.0 4 0 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 AIN96317.1 - 8.9e-09 35.1 0.0 0.05 13.0 0.0 3.5 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_15 PF13175.6 AIN96317.1 - 4.3e-05 23.4 0.0 1.3 8.7 0.0 3.9 4 0 0 4 4 4 2 AAA ATPase domain SbcCD_C PF13558.6 AIN96317.1 - 4.9e-05 23.5 0.1 0.25 11.6 0.1 4.2 3 2 0 3 3 3 1 Putative exonuclease SbcCD, C subunit RsgA_GTPase PF03193.16 AIN96317.1 - 5.9e-05 23.0 0.1 0.046 13.6 0.0 2.7 2 0 0 2 2 2 2 RsgA GTPase AAA_23 PF13476.6 AIN96317.1 - 0.00012 22.6 0.3 0.4 11.1 0.0 2.4 2 0 0 2 2 2 2 AAA domain SRP54 PF00448.22 AIN96317.1 - 0.00059 19.5 0.3 0.43 10.2 0.0 2.4 2 0 0 2 2 2 2 SRP54-type protein, GTPase domain AAA_29 PF13555.6 AIN96317.1 - 0.0014 18.4 0.1 0.3 10.9 0.0 2.7 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_30 PF13604.6 AIN96317.1 - 0.0017 18.1 0.0 0.21 11.3 0.0 2.5 2 0 0 2 2 2 1 AAA domain KdpD PF02702.17 AIN96317.1 - 0.0073 15.8 0.0 0.017 14.6 0.0 1.5 1 0 0 1 1 1 1 Osmosensitive K+ channel His kinase sensor domain Zeta_toxin PF06414.12 AIN96317.1 - 0.02 14.2 0.0 16 4.7 0.0 3.4 3 1 0 3 3 3 0 Zeta toxin AAA PF00004.29 AIN96317.1 - 0.057 13.8 0.0 2.2 8.7 0.0 3.1 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 AIN96317.1 - 0.081 13.3 0.1 25 5.3 0.0 2.9 2 0 0 2 2 2 0 RNA helicase Arf PF00025.21 AIN96317.1 - 0.081 12.4 0.1 3.9 6.9 0.0 2.4 2 0 0 2 2 2 0 ADP-ribosylation factor family MMR_HSR1 PF01926.23 AIN96317.1 - 0.089 12.9 0.1 11 6.1 0.0 3.1 2 0 0 2 2 2 0 50S ribosome-binding GTPase MukB PF04310.12 AIN96317.1 - 0.25 11.1 1.5 18 5.0 0.0 2.6 2 0 0 2 2 2 0 MukB N-terminal HEAT PF02985.22 AIN96319.1 - 0.00076 19.5 2.1 4.5 7.8 0.0 4.6 5 0 0 5 5 5 2 HEAT repeat Adaptin_N PF01602.20 AIN96319.1 - 0.013 14.1 2.2 0.42 9.1 0.1 2.4 2 1 0 2 2 2 0 Adaptin N terminal region HEAT_2 PF13646.6 AIN96319.1 - 6.8 7.2 12.3 0.31 11.5 0.3 3.9 3 3 2 5 5 5 0 HEAT repeats Ycf66_N PF07444.11 AIN96320.1 - 0.04 14.0 2.6 3.3 7.9 0.1 3.8 3 1 1 4 4 4 0 Ycf66 protein N-terminus Hydrolase_like PF13242.6 AIN96320.1 - 0.084 12.9 0.1 0.17 11.9 0.1 1.5 1 0 0 1 1 1 0 HAD-hyrolase-like DUF5546 PF17700.1 AIN96320.1 - 0.27 11.6 3.0 0.21 11.9 0.6 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5546) DUF3302 PF11742.8 AIN96320.1 - 0.36 11.0 3.6 0.42 10.8 0.4 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3302) PapD-like PF14874.6 AIN96321.1 - 5.6e-47 158.1 0.6 1.5e-46 156.8 0.6 1.8 1 0 0 1 1 1 1 Flagellar-associated PapD-like Nodulin-like PF06813.13 AIN96322.1 - 3.6e-15 56.1 14.0 3.6e-15 56.1 14.0 3.1 2 2 1 3 3 3 2 Nodulin-like MFS_1 PF07690.16 AIN96322.1 - 1e-07 31.3 43.4 3.3e-06 26.3 11.5 2.8 2 1 0 2 2 2 2 Major Facilitator Superfamily BLOC1_2 PF10046.9 AIN96324.1 - 0.0003 21.0 5.4 0.0034 17.7 5.4 2.0 1 1 0 1 1 1 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 THOC7 PF05615.13 AIN96324.1 - 0.0005 20.4 0.1 0.0006 20.1 0.1 1.3 1 0 0 1 1 1 1 Tho complex subunit 7 Uso1_p115_C PF04871.13 AIN96324.1 - 0.0087 16.4 7.4 0.012 16.0 7.4 1.1 1 0 0 1 1 1 1 Uso1 / p115 like vesicle tethering protein, C terminal region KxDL PF10241.9 AIN96324.1 - 0.019 15.2 1.8 0.027 14.8 1.1 1.6 1 1 0 1 1 1 0 Uncharacterized conserved protein DUF3450 PF11932.8 AIN96324.1 - 0.028 13.7 1.9 0.04 13.2 1.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) HAUS-augmin3 PF14932.6 AIN96324.1 - 0.041 13.5 2.9 0.055 13.0 2.9 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 Ead_Ea22 PF13935.6 AIN96324.1 - 0.043 14.5 2.5 0.064 13.9 2.5 1.3 1 0 0 1 1 1 0 Ead/Ea22-like protein DivIC PF04977.15 AIN96324.1 - 0.044 13.6 0.8 0.044 13.6 0.8 2.1 1 1 1 2 2 2 0 Septum formation initiator Spc7 PF08317.11 AIN96324.1 - 0.051 12.5 2.5 0.067 12.1 2.5 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein KELK PF15796.5 AIN96324.1 - 0.064 13.7 1.1 0.064 13.7 1.1 1.7 2 0 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF4175 PF13779.6 AIN96324.1 - 0.084 10.8 2.8 0.094 10.6 2.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) CENP-H PF05837.12 AIN96324.1 - 0.49 10.8 4.9 0.82 10.1 4.9 1.4 1 0 0 1 1 1 0 Centromere protein H (CENP-H) YabA PF06156.13 AIN96324.1 - 0.82 10.3 3.8 2 9.1 3.8 1.7 1 1 0 1 1 1 0 Initiation control protein YabA ZapB PF06005.12 AIN96324.1 - 1.9 9.0 9.9 4.4 7.8 9.9 1.7 1 1 0 1 1 1 0 Cell division protein ZapB DUF4140 PF13600.6 AIN96324.1 - 2.9 8.4 7.6 34 5.0 7.6 2.2 1 1 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) Ribosomal_L4 PF00573.22 AIN96325.1 - 3.6e-10 39.8 0.0 1.1e-09 38.3 0.0 1.7 1 1 0 1 1 1 1 Ribosomal protein L4/L1 family STIMATE PF12400.8 AIN96326.1 - 0.0011 19.5 4.1 0.0011 19.5 4.1 1.8 2 0 0 2 2 2 1 STIMATE family SH3_9 PF14604.6 AIN96328.1 - 1.7e-10 40.6 0.0 9.7e-10 38.2 0.0 2.0 2 0 0 2 2 2 1 Variant SH3 domain SH3_1 PF00018.28 AIN96328.1 - 5.5e-10 38.7 0.0 1.1e-09 37.7 0.0 1.6 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 AIN96328.1 - 2.5e-09 36.6 0.0 1.1e-07 31.4 0.0 2.5 2 0 0 2 2 2 1 Variant SH3 domain Spectrin PF00435.21 AIN96328.1 - 0.53 10.8 6.1 6.5 7.3 0.8 2.7 2 0 0 2 2 2 0 Spectrin repeat IF-2B PF01008.17 AIN96329.1 - 8.1e-23 81.0 1.0 6.9e-18 64.8 0.6 3.0 2 2 0 2 2 2 2 Initiation factor 2 subunit family RMMBL PF07521.12 AIN96329.1 - 0.083 12.8 0.0 0.16 11.9 0.0 1.4 1 0 0 1 1 1 0 Zn-dependent metallo-hydrolase RNA specificity domain PITH PF06201.13 AIN96330.1 - 8.7e-21 74.7 0.0 1.1e-20 74.4 0.0 1.1 1 0 0 1 1 1 1 PITH domain Proteasome PF00227.26 AIN96331.1 - 2.2e-42 144.7 0.4 2.6e-42 144.5 0.4 1.1 1 0 0 1 1 1 1 Proteasome subunit DAP3 PF10236.9 AIN96332.1 - 7.2e-23 81.2 0.0 1.5e-19 70.3 0.0 2.1 2 0 0 2 2 2 2 Mitochondrial ribosomal death-associated protein 3 T2SSE PF00437.20 AIN96332.1 - 0.0047 16.0 0.0 0.0069 15.5 0.0 1.1 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_16 PF13191.6 AIN96332.1 - 0.029 14.8 0.0 0.059 13.8 0.0 1.6 1 1 0 1 1 1 0 AAA ATPase domain ATPase_2 PF01637.18 AIN96332.1 - 0.07 13.0 0.0 0.18 11.7 0.0 1.6 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea RecA_dep_nuc PF16786.5 AIN96332.1 - 0.12 12.5 0.0 0.26 11.5 0.0 1.5 1 0 0 1 1 1 0 Recombination enhancement, RecA-dependent nuclease AAA_29 PF13555.6 AIN96332.1 - 0.17 11.6 0.0 0.38 10.5 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Isochorismatase PF00857.20 AIN96335.1 - 6.2e-14 52.5 0.1 1e-13 51.9 0.1 1.3 1 1 0 1 1 1 1 Isochorismatase family Apyrase PF06079.11 AIN96338.1 - 0.012 14.8 0.0 0.044 13.0 0.0 1.7 2 0 0 2 2 2 0 Apyrase TPR_19 PF14559.6 AIN96339.1 - 0.033 14.7 1.7 1.3 9.6 0.2 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat Plus-3 PF03126.18 AIN96340.1 - 2.2e-20 73.2 0.0 3.9e-20 72.4 0.0 1.4 1 0 0 1 1 1 1 Plus-3 domain zf-C3HC4_3 PF13920.6 AIN96340.1 - 4.4e-06 26.4 21.2 7e-06 25.8 21.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Vps39_2 PF10367.9 AIN96340.1 - 0.059 13.8 3.9 0.12 12.8 3.9 1.6 1 0 0 1 1 1 0 Vacuolar sorting protein 39 domain 2 SF1-HH PF16275.5 AIN96340.1 - 0.49 10.8 2.7 0.25 11.7 0.6 1.6 2 0 0 2 2 2 0 Splicing factor 1 helix-hairpin domain Ocular_alb PF02101.15 AIN96341.1 - 0.043 12.7 1.1 0.12 11.3 1.1 1.7 1 0 0 1 1 1 0 Ocular albinism type 1 protein TolA_bind_tri PF16331.5 AIN96342.1 - 0.0046 17.0 6.3 0.0046 17.0 6.3 8.5 7 3 3 10 10 10 3 TolA binding protein trimerisation RPW8 PF05659.11 AIN96342.1 - 0.099 12.3 0.0 0.099 12.3 0.0 3.8 2 1 0 3 3 3 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 Sec8_exocyst PF04048.14 AIN96342.1 - 3.3 7.6 13.4 0.11 12.3 1.3 4.4 3 1 0 4 4 4 0 Sec8 exocyst complex component specific domain XhlA PF10779.9 AIN96342.1 - 3.4 7.9 22.1 3.7 7.8 0.2 6.9 7 1 1 8 8 8 0 Haemolysin XhlA Pkinase PF00069.25 AIN96343.1 - 2.7e-39 135.1 0.0 2.4e-19 69.7 0.0 3.3 2 2 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 AIN96343.1 - 2.5e-19 69.6 0.0 1.6e-11 44.0 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.23 AIN96343.1 - 0.0086 16.0 0.3 0.52 10.2 0.0 2.5 1 1 0 2 2 2 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 AIN96343.1 - 0.1 11.3 0.0 0.15 10.8 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase LRR_4 PF12799.7 AIN96345.1 - 6.1e-08 32.8 3.3 0.011 16.2 0.1 3.6 3 2 1 4 4 4 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 AIN96345.1 - 3.7e-07 29.8 1.2 0.013 15.3 0.0 3.5 2 1 1 3 3 3 3 Leucine rich repeat LRR_9 PF14580.6 AIN96345.1 - 0.029 13.9 0.0 3.4 7.1 0.0 2.2 2 0 0 2 2 2 0 Leucine-rich repeat UCH PF00443.29 AIN96348.1 - 2.9e-23 82.7 0.0 8.7e-22 77.8 0.0 2.4 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 AIN96348.1 - 0.0027 17.3 0.0 12 5.4 0.0 3.8 3 1 0 4 4 4 3 Ubiquitin carboxyl-terminal hydrolase AAA PF00004.29 AIN96350.1 - 6e-45 152.9 0.0 1.1e-44 152.1 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 AIN96350.1 - 2.2e-09 37.0 0.0 4.8e-09 35.9 0.0 1.6 1 0 0 1 1 1 1 AAA+ lid domain Prot_ATP_ID_OB PF16450.5 AIN96350.1 - 3.8e-09 36.4 0.1 1.4e-08 34.5 0.0 2.1 2 0 0 2 2 1 1 Proteasomal ATPase OB C-terminal domain AAA_5 PF07728.14 AIN96350.1 - 1.8e-08 34.4 0.1 5.7e-08 32.9 0.1 1.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 AIN96350.1 - 1.2e-07 32.3 0.2 1.6e-05 25.4 0.0 2.4 1 1 1 2 2 2 1 AAA ATPase domain AAA_2 PF07724.14 AIN96350.1 - 1.2e-06 28.7 0.0 2.7e-06 27.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 AIN96350.1 - 5e-05 23.6 0.7 0.0066 16.7 0.7 2.6 1 1 0 1 1 1 1 AAA domain DUF815 PF05673.13 AIN96350.1 - 7.5e-05 22.0 0.0 0.00013 21.2 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF815) RuvB_N PF05496.12 AIN96350.1 - 0.00041 20.1 0.0 0.001 18.8 0.0 1.7 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_7 PF12775.7 AIN96350.1 - 0.00042 19.9 0.1 0.0018 17.8 0.0 2.0 2 1 0 2 2 2 1 P-loop containing dynein motor region AAA_28 PF13521.6 AIN96350.1 - 0.00043 20.6 0.0 0.00076 19.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 AIN96350.1 - 0.00063 20.3 0.0 0.0013 19.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain NACHT PF05729.12 AIN96350.1 - 0.0014 18.6 0.3 0.041 13.8 0.0 2.9 2 1 1 3 3 3 1 NACHT domain NTPase_1 PF03266.15 AIN96350.1 - 0.0015 18.4 0.2 0.0071 16.3 0.1 2.2 3 0 0 3 3 3 1 NTPase AAA_30 PF13604.6 AIN96350.1 - 0.002 17.9 0.1 0.0053 16.5 0.1 1.8 1 1 0 1 1 1 1 AAA domain AAA_3 PF07726.11 AIN96350.1 - 0.0027 17.5 0.1 0.01 15.7 0.0 2.0 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) TniB PF05621.11 AIN96350.1 - 0.0029 17.0 0.0 0.26 10.6 0.0 2.5 3 0 0 3 3 2 1 Bacterial TniB protein AAA_33 PF13671.6 AIN96350.1 - 0.0035 17.5 0.0 0.0066 16.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.6 AIN96350.1 - 0.0037 17.3 0.0 0.0089 16.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 AIN96350.1 - 0.0076 15.7 0.1 0.018 14.4 0.1 1.6 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI TsaE PF02367.17 AIN96350.1 - 0.0095 15.9 0.0 0.015 15.2 0.0 1.4 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE TIP49 PF06068.13 AIN96350.1 - 0.012 14.8 0.0 0.035 13.3 0.0 1.6 1 1 0 2 2 2 0 TIP49 P-loop domain AAA_24 PF13479.6 AIN96350.1 - 0.019 14.7 0.2 0.043 13.5 0.1 1.7 1 1 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 AIN96350.1 - 0.024 14.6 0.1 0.35 10.7 0.0 2.1 1 1 1 2 2 2 0 ATPase domain predominantly from Archaea Sigma54_activat PF00158.26 AIN96350.1 - 0.024 14.3 0.1 0.76 9.5 0.0 2.4 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_19 PF13245.6 AIN96350.1 - 0.027 14.8 0.2 0.075 13.4 0.1 1.7 2 0 0 2 2 1 0 AAA domain RNA_helicase PF00910.22 AIN96350.1 - 0.027 14.9 0.0 0.052 14.0 0.0 1.5 1 0 0 1 1 1 0 RNA helicase IstB_IS21 PF01695.17 AIN96350.1 - 0.029 14.1 0.0 0.063 13.0 0.0 1.6 1 1 0 1 1 1 0 IstB-like ATP binding protein AAA_25 PF13481.6 AIN96350.1 - 0.03 13.9 0.7 0.19 11.3 0.1 2.1 1 1 0 2 2 2 0 AAA domain Bac_DnaA PF00308.18 AIN96350.1 - 0.039 13.8 0.0 0.068 13.0 0.0 1.4 1 0 0 1 1 1 0 Bacterial dnaA protein ABC_tran PF00005.27 AIN96350.1 - 0.048 14.2 0.0 0.16 12.5 0.0 2.1 1 1 0 1 1 1 0 ABC transporter cobW PF02492.19 AIN96350.1 - 0.072 12.7 0.0 0.16 11.5 0.0 1.5 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_11 PF13086.6 AIN96350.1 - 0.079 12.7 0.0 0.13 12.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain ATPase PF06745.13 AIN96350.1 - 0.14 11.5 0.7 0.86 8.9 0.0 2.3 3 0 0 3 3 3 0 KaiC NB-ARC PF00931.22 AIN96350.1 - 0.16 11.1 0.0 1.2 8.2 0.0 2.1 2 0 0 2 2 2 0 NB-ARC domain HAGH_C PF16123.5 AIN96351.1 - 2.6e-07 31.0 0.1 7.2e-07 29.6 0.0 1.8 2 0 0 2 2 2 1 Hydroxyacylglutathione hydrolase C-terminus Lactamase_B PF00753.27 AIN96351.1 - 2.6e-05 24.3 5.1 7e-05 22.9 5.1 1.8 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 AIN96351.1 - 0.026 14.0 0.1 0.05 13.1 0.1 1.6 1 0 0 1 1 1 0 Beta-lactamase superfamily domain FAM199X PF15814.5 AIN96352.1 - 0.76 8.8 9.1 2.5 7.1 9.1 1.9 1 0 0 1 1 1 0 Protein family FAM199X tRNA-synt_1e PF01406.19 AIN96354.1 - 1.8e-112 375.6 0.0 2.7e-112 375.0 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1g PF09334.11 AIN96354.1 - 0.0014 17.5 0.3 0.022 13.6 0.0 2.6 3 0 0 3 3 3 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.22 AIN96354.1 - 0.016 13.5 0.0 0.24 9.6 0.0 2.7 3 0 0 3 3 3 0 tRNA synthetases class I (I, L, M and V) tRNA-synt_1c PF00749.21 AIN96354.1 - 0.025 13.5 0.4 0.066 12.1 0.0 2.0 2 0 0 2 2 2 0 tRNA synthetases class I (E and Q), catalytic domain Peptidase_S78_2 PF14550.6 AIN96354.1 - 0.053 13.6 0.0 0.34 11.0 0.0 2.2 2 0 0 2 2 2 0 Putative phage serine protease XkdF Helicase_C PF00271.31 AIN96355.1 - 3.9e-05 24.0 0.0 0.00013 22.3 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain HA2 PF04408.23 AIN96355.1 - 9.8e-05 22.6 0.0 0.00043 20.5 0.0 2.1 1 0 0 1 1 1 1 Helicase associated domain (HA2) zf-C2H2_jaz PF12171.8 AIN96355.1 - 0.0093 16.2 2.0 0.018 15.3 2.0 1.5 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 AIN96355.1 - 2.9 8.4 5.1 7.1 7.2 5.1 1.7 1 0 0 1 1 1 0 Zinc-finger of C2H2 type SET PF00856.28 AIN96356.1 - 7.9e-07 29.6 0.3 0.0091 16.4 0.0 3.3 2 1 0 2 2 2 2 SET domain DUF681 PF05080.12 AIN96356.1 - 0.063 13.9 0.2 0.24 12.1 0.2 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF681) Orn_Arg_deC_N PF02784.16 AIN96357.1 - 4.8e-79 265.2 0.0 6.6e-79 264.8 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.22 AIN96357.1 - 2.1e-13 50.3 0.0 9.4e-13 48.2 0.0 2.2 1 1 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain Ala_racemase_N PF01168.20 AIN96357.1 - 0.00075 19.2 0.1 0.0023 17.6 0.0 1.8 2 0 0 2 2 2 1 Alanine racemase, N-terminal domain KxDL PF10241.9 AIN96358.1 - 0.011 16.0 1.8 0.011 16.0 1.8 7.8 5 2 2 7 7 7 0 Uncharacterized conserved protein SAC3_GANP PF03399.16 AIN96359.1 - 1.9e-13 50.5 1.9 1.9e-12 47.2 1.9 2.2 1 1 0 1 1 1 1 SAC3/GANP family Myotub-related PF06602.14 AIN96361.1 - 3.3e-57 194.0 0.0 3.1e-31 108.6 0.0 2.6 3 0 0 3 3 3 2 Myotubularin-like phosphatase domain NOT2_3_5 PF04153.18 AIN96364.1 - 3.9e-22 78.7 0.3 3.9e-22 78.7 0.3 3.5 3 0 0 3 3 3 1 NOT2 / NOT3 / NOT5 family DUF572 PF04502.13 AIN96364.1 - 0.058 13.0 11.0 0.12 11.9 11.0 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF572) Ctr PF04145.15 AIN96364.1 - 1.3 9.6 10.4 1.7 9.3 0.3 2.8 2 0 0 2 2 2 0 Ctr copper transporter family GST_N_3 PF13417.6 AIN96365.1 - 1.9e-09 37.8 0.0 1e-08 35.4 0.0 2.1 1 1 1 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 AIN96365.1 - 2.1e-09 37.6 0.0 3.7e-09 36.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 AIN96365.1 - 9e-07 29.1 0.0 2.3e-06 27.8 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 AIN96365.1 - 0.0007 19.7 0.1 0.0027 17.9 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 AIN96365.1 - 0.0094 16.1 0.0 0.017 15.3 0.0 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain PUF PF00806.19 AIN96367.1 - 1.1e-33 113.0 5.7 0.00018 21.0 0.1 7.6 7 0 0 7 7 7 7 Pumilio-family RNA binding repeat Phos_pyr_kin PF08543.12 AIN96367.1 - 0.054 12.9 0.0 0.13 11.7 0.0 1.6 1 0 0 1 1 1 0 Phosphomethylpyrimidine kinase DUF832 PF05734.11 AIN96367.1 - 0.86 9.0 2.8 0.87 9.0 0.3 2.1 3 0 0 3 3 3 0 Herpesvirus protein of unknown function (DUF832) Epimerase PF01370.21 AIN96368.1 - 0.00087 18.8 0.0 0.0019 17.7 0.0 1.6 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 AIN96368.1 - 0.0058 16.5 2.7 0.0059 16.5 0.1 2.3 3 0 0 3 3 3 1 NAD(P)H-binding DapB_N PF01113.20 AIN96368.1 - 0.011 15.9 0.1 0.033 14.3 0.1 1.8 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus NmrA PF05368.13 AIN96368.1 - 0.03 13.9 0.2 0.065 12.8 0.2 1.6 1 0 0 1 1 1 0 NmrA-like family DXP_reductoisom PF02670.16 AIN96368.1 - 0.35 11.6 0.2 0.35 11.6 0.2 2.1 3 0 0 3 3 3 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase S1-P1_nuclease PF02265.16 AIN96369.1 - 5.5e-60 203.3 0.0 6.6e-60 203.0 0.0 1.1 1 0 0 1 1 1 1 S1/P1 Nuclease DUF866 PF05907.13 AIN96371.1 - 1.5e-32 112.7 0.0 1.8e-32 112.4 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF866) Elf1 PF05129.13 AIN96371.1 - 0.039 14.0 0.0 0.074 13.1 0.0 1.5 1 0 0 1 1 1 0 Transcription elongation factor Elf1 like DUF3222 PF11519.8 AIN96371.1 - 0.081 13.2 0.2 0.28 11.4 0.0 2.0 2 1 1 3 3 3 0 Protein of unknown function (DUF3222) Bromodomain PF00439.25 AIN96372.1 - 0.075 13.1 0.0 19 5.4 0.0 2.3 2 0 0 2 2 2 0 Bromodomain IL2RB_N1 PF18707.1 AIN96374.1 - 0.17 12.4 0.0 0.34 11.5 0.0 1.4 1 0 0 1 1 1 0 Interleukin-2 receptor subunit beta N-terminal domain 1 WW PF00397.26 AIN96380.1 - 2.5e-09 37.1 0.1 4.9e-09 36.1 0.1 1.5 1 0 0 1 1 1 1 WW domain ATP-synt_F PF01990.17 AIN96381.1 - 5.8e-34 116.3 0.0 7e-34 116.0 0.0 1.1 1 0 0 1 1 1 1 ATP synthase (F/14-kDa) subunit PGI PF00342.19 AIN96382.1 - 3.9e-257 853.6 2.7 4.5e-257 853.4 2.7 1.0 1 0 0 1 1 1 1 Phosphoglucose isomerase DUF4473 PF14747.6 AIN96382.1 - 0.061 13.9 0.0 0.21 12.2 0.0 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4473) OsmC PF02566.19 AIN96383.1 - 0.012 16.0 0.0 0.025 15.0 0.0 1.4 1 1 0 1 1 1 0 OsmC-like protein DUF2574 PF10836.8 AIN96384.1 - 0.17 11.8 0.7 6.3 6.7 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2574) TPR_19 PF14559.6 AIN96385.1 - 0.0045 17.5 30.3 0.26 11.8 1.4 6.7 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_8 PF13181.6 AIN96385.1 - 0.011 15.9 10.3 9.9 6.7 0.6 7.5 9 0 0 9 9 9 0 Tetratricopeptide repeat TPR_1 PF00515.28 AIN96385.1 - 0.019 14.8 8.2 0.77 9.7 1.1 5.8 7 0 0 7 7 7 0 Tetratricopeptide repeat ANAPC3 PF12895.7 AIN96385.1 - 0.11 12.8 14.0 0.033 14.4 1.6 4.1 4 0 0 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 AWPM-19 PF05512.11 AIN96385.1 - 0.11 12.7 0.9 0.3 11.3 0.9 1.8 1 0 0 1 1 1 0 AWPM-19-like family TPR_2 PF07719.17 AIN96385.1 - 0.12 12.5 24.2 0.094 12.9 2.6 8.0 9 2 2 11 11 11 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 AIN96385.1 - 0.52 10.4 4.9 0.46 10.6 0.6 3.1 5 0 0 5 5 5 0 Fis1 C-terminal tetratricopeptide repeat DUF1771 PF08590.10 AIN96385.1 - 0.61 10.5 6.1 8.9 6.8 0.3 3.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1771) FUSC_2 PF13515.6 AIN96386.1 - 1e-15 58.0 9.1 1e-15 58.0 9.1 2.6 2 0 0 2 2 2 2 Fusaric acid resistance protein-like FSAP_sig_propep PF03032.15 AIN96386.1 - 7.2 6.7 9.1 0.15 12.1 0.4 2.6 2 0 0 2 2 2 0 Frog skin active peptide family signal and propeptide FUSC_2 PF13515.6 AIN96387.1 - 8.3e-13 48.6 4.8 8.3e-13 48.6 4.8 2.5 2 0 0 2 2 2 1 Fusaric acid resistance protein-like ALMT PF11744.8 AIN96387.1 - 1.4 7.6 5.8 0.18 10.6 0.3 2.0 2 0 0 2 2 2 0 Aluminium activated malate transporter DUF3021 PF11457.8 AIN96387.1 - 1.5 9.2 8.7 0.83 10.0 1.7 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF3021) Sulfatase PF00884.23 AIN96388.1 - 6e-05 22.6 0.1 0.0014 18.1 0.0 2.2 2 0 0 2 2 2 1 Sulfatase PsbW PF07123.12 AIN96388.1 - 0.04 13.9 1.5 4.2 7.4 0.0 2.9 3 0 0 3 3 3 0 Photosystem II reaction centre W protein (PsbW) Phosphodiest PF01663.22 AIN96388.1 - 0.07 12.7 0.0 2.7 7.5 0.0 2.4 2 1 0 2 2 2 0 Type I phosphodiesterase / nucleotide pyrophosphatase TPR_1 PF00515.28 AIN96389.1 - 3.1e-17 61.6 12.6 6.7e-05 22.5 0.0 6.0 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_2 PF07719.17 AIN96389.1 - 8.2e-17 59.9 20.7 0.0018 18.3 0.1 8.1 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_8 PF13181.6 AIN96389.1 - 1.5e-16 59.2 0.4 2.6e-05 24.1 0.0 6.6 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_11 PF13414.6 AIN96389.1 - 1.9e-11 43.5 16.8 1.6e-05 24.5 0.1 4.7 4 1 1 5 5 5 2 TPR repeat TPR_14 PF13428.6 AIN96389.1 - 8.9e-11 41.7 20.9 0.00011 22.8 0.2 7.3 6 3 3 9 9 7 3 Tetratricopeptide repeat TPR_16 PF13432.6 AIN96389.1 - 1.4e-10 41.6 5.8 1e-06 29.3 0.6 6.8 6 1 1 7 7 6 3 Tetratricopeptide repeat TPR_19 PF14559.6 AIN96389.1 - 3.3e-10 40.3 10.4 5.1e-05 23.7 0.1 5.1 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_12 PF13424.6 AIN96389.1 - 5.6e-07 29.7 21.7 1.2 9.5 0.0 6.2 4 1 1 5 5 5 4 Tetratricopeptide repeat TPR_15 PF13429.6 AIN96389.1 - 1.2e-05 24.6 5.3 3.7e-05 23.1 5.3 1.8 1 0 0 1 1 1 1 Tetratricopeptide repeat ANAPC8 PF04049.13 AIN96389.1 - 0.00071 19.6 0.0 0.0031 17.6 0.0 2.0 1 1 0 1 1 1 1 Anaphase promoting complex subunit 8 / Cdc23 TPR_9 PF13371.6 AIN96389.1 - 0.0011 19.0 18.7 0.16 12.1 0.7 6.0 4 1 2 6 6 6 2 Tetratricopeptide repeat TPR_17 PF13431.6 AIN96389.1 - 0.0015 18.8 1.9 1.8 9.1 0.2 4.5 4 0 0 4 4 3 1 Tetratricopeptide repeat ANAPC3 PF12895.7 AIN96389.1 - 0.0018 18.4 17.2 0.018 15.3 0.6 5.5 5 1 1 6 6 6 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.6 AIN96389.1 - 0.003 17.5 16.0 2.6 8.3 0.2 6.4 6 0 0 6 6 6 1 Tetratricopeptide repeat FAT PF02259.23 AIN96389.1 - 0.012 14.9 0.2 0.21 10.8 0.1 2.5 1 1 2 3 3 3 0 FAT domain PCP_red PF08369.10 AIN96389.1 - 0.031 14.5 0.0 0.085 13.1 0.0 1.8 1 0 0 1 1 1 0 Proto-chlorophyllide reductase 57 kD subunit TPR_10 PF13374.6 AIN96389.1 - 0.05 13.5 11.4 0.36 10.8 0.5 4.2 4 0 0 4 4 3 0 Tetratricopeptide repeat TPR_6 PF13174.6 AIN96389.1 - 0.08 13.6 6.5 2 9.2 0.0 4.8 6 0 0 6 6 4 0 Tetratricopeptide repeat Aminotran_1_2 PF00155.21 AIN96391.1 - 3.9e-32 111.8 0.0 5e-32 111.5 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II PPL5 PF18168.1 AIN96392.1 - 3.4e-147 489.9 0.0 5.4e-147 489.2 0.0 1.3 1 0 0 1 1 1 1 Prim-pol family 5 PriCT_2 PF08707.11 AIN96392.1 - 8.2e-12 45.3 0.3 2.2e-11 43.9 0.3 1.7 1 0 0 1 1 1 1 Primase C terminal 2 (PriCT-2) Metallophos PF00149.28 AIN96394.1 - 1.4e-27 97.6 0.0 2.4e-27 96.8 0.0 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase zf-TRAF PF02176.18 AIN96394.1 - 0.00033 21.3 3.2 0.00033 21.3 3.2 3.3 1 1 2 3 3 3 1 TRAF-type zinc finger EF-hand_1 PF00036.32 AIN96394.1 - 0.0027 17.1 0.1 0.1 12.2 0.1 3.1 3 0 0 3 3 3 1 EF hand EF-hand_6 PF13405.6 AIN96394.1 - 0.0082 16.0 1.2 0.39 10.8 0.0 3.8 3 1 1 4 4 4 1 EF-hand domain EF-hand_7 PF13499.6 AIN96394.1 - 0.0088 16.5 0.2 0.21 12.0 0.0 2.9 3 1 1 4 4 4 2 EF-hand domain pair zinc_ribbon_2 PF13240.6 AIN96394.1 - 0.46 10.3 8.9 0.5 10.2 2.0 3.7 3 1 0 3 3 3 0 zinc-ribbon domain BBL5 PF07289.11 AIN96396.1 - 2.7e-130 434.3 0.0 3.2e-130 434.0 0.0 1.0 1 0 0 1 1 1 1 Bardet-Biedl syndrome 5 protein Voldacs PF03517.13 AIN96396.1 - 0.00022 21.4 0.1 0.56 10.3 0.0 2.6 2 0 0 2 2 2 2 Regulator of volume decrease after cellular swelling Vps36_ESCRT-II PF11605.8 AIN96396.1 - 0.00035 20.7 0.0 0.17 12.1 0.0 2.3 2 0 0 2 2 2 2 Vacuolar protein sorting protein 36 Vps36 bPH_3 PF14470.6 AIN96396.1 - 0.016 15.6 0.0 8.5 6.8 0.0 2.4 2 0 0 2 2 2 0 Bacterial PH domain PH_TFIIH PF08567.11 AIN96396.1 - 0.023 15.0 0.0 2.2 8.7 0.0 2.7 3 0 0 3 3 3 0 TFIIH p62 subunit, N-terminal domain LRR_6 PF13516.6 AIN96398.1 - 2.2e-21 74.0 23.8 0.15 12.2 0.1 11.3 11 0 0 11 11 11 9 Leucine Rich repeat LRR_4 PF12799.7 AIN96398.1 - 5.7e-09 36.1 12.4 0.28 11.7 0.0 7.7 6 3 2 8 8 8 5 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 AIN96398.1 - 1.1e-07 31.4 4.7 6.9 7.6 0.0 7.7 8 1 0 8 8 8 2 Leucine Rich Repeat LRR_8 PF13855.6 AIN96398.1 - 2e-05 24.3 15.8 0.87 9.4 0.2 6.8 6 2 0 6 6 6 3 Leucine rich repeat DUF962 PF06127.11 AIN96399.1 - 3.9e-24 84.6 0.2 4.4e-24 84.4 0.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF962) TMEM65 PF10507.9 AIN96399.1 - 0.0089 16.0 1.6 0.021 14.7 1.6 1.6 1 1 1 2 2 2 1 Transmembrane protein 65 MerC PF03203.14 AIN96399.1 - 0.033 14.7 2.2 0.049 14.1 2.2 1.4 1 1 0 1 1 1 0 MerC mercury resistance protein Ion_trans PF00520.31 AIN96399.1 - 0.045 13.0 0.1 0.052 12.8 0.1 1.0 1 0 0 1 1 1 0 Ion transport protein DUF4491 PF14898.6 AIN96399.1 - 0.055 13.9 0.3 0.07 13.6 0.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4491) Phage_holin_2_4 PF16082.5 AIN96399.1 - 0.14 11.9 1.9 0.21 11.3 1.9 1.3 1 0 0 1 1 1 0 Bacteriophage holin family, superfamily II-like DUF962 PF06127.11 AIN96400.1 - 8.1e-26 90.0 0.1 9.1e-26 89.8 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF962) UPF0126 PF03458.13 AIN96400.1 - 0.0082 16.0 2.0 0.013 15.4 2.0 1.3 1 0 0 1 1 1 1 UPF0126 domain Ydr279_N PF17745.1 AIN96401.1 - 6.1e-06 26.4 0.0 1.5e-05 25.2 0.0 1.6 1 0 0 1 1 1 1 Ydr279p protein triple barrel domain RNase_H2-Ydr279 PF09468.10 AIN96401.1 - 0.0037 17.5 0.0 0.0069 16.6 0.0 1.4 1 0 0 1 1 1 1 Ydr279p protein family (RNase H2 complex component) wHTH domain LRR_8 PF13855.6 AIN96403.1 - 3.7e-23 81.1 7.1 0.0046 16.7 0.3 9.3 2 2 7 11 11 11 9 Leucine rich repeat LRR_4 PF12799.7 AIN96403.1 - 1.5e-20 72.9 6.9 0.054 13.9 0.0 10.3 6 3 3 12 12 12 7 Leucine Rich repeats (2 copies) Chorismate_bind PF00425.18 AIN96403.1 - 8.1e-05 22.3 2.1 21 4.6 0.0 5.6 3 1 4 7 7 7 1 chorismate binding enzyme LRRNT_2 PF08263.12 AIN96403.1 - 0.0012 19.1 0.5 0.0012 19.1 0.5 2.4 2 0 0 2 2 2 1 Leucine rich repeat N-terminal domain MOR2-PAG1_C PF14225.6 AIN96403.1 - 0.12 12.2 0.0 0.12 12.2 0.0 4.9 2 1 2 5 5 5 0 Cell morphogenesis C-terminal LRR_1 PF00560.33 AIN96403.1 - 0.19 12.4 1.7 2e+02 3.2 0.1 5.7 5 0 0 5 5 5 0 Leucine Rich Repeat TPPII_N PF12583.8 AIN96403.1 - 7.3 7.2 12.1 17 6.0 12.1 1.7 1 0 0 1 1 1 0 Tripeptidyl peptidase II N terminal LRRNT_2 PF08263.12 AIN96404.1 - 0.00058 20.1 0.5 0.00058 20.1 0.5 2.0 2 0 0 2 2 2 1 Leucine rich repeat N-terminal domain TetR_C_30 PF17939.1 AIN96405.1 - 0.18 12.0 6.7 0.075 13.3 0.3 3.5 4 0 0 4 4 4 0 Tetracyclin repressor-like, C-terminal domain DnaJ PF00226.31 AIN96406.1 - 5.4e-14 52.1 0.0 1.1e-13 51.0 0.0 1.6 1 0 0 1 1 1 1 DnaJ domain zf-C3HC4_3 PF13920.6 AIN96406.1 - 0.93 9.4 15.4 1.8 8.5 15.4 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) PDZ PF00595.24 AIN96407.1 - 0.013 15.8 0.0 0.04 14.3 0.0 1.8 1 0 0 1 1 1 0 PDZ domain PDZ_6 PF17820.1 AIN96407.1 - 0.029 14.2 0.0 0.079 12.8 0.0 1.7 1 0 0 1 1 1 0 PDZ domain PDZ_2 PF13180.6 AIN96407.1 - 0.05 13.9 0.0 0.14 12.5 0.0 1.7 1 0 0 1 1 1 0 PDZ domain Oxidored_FMN PF00724.20 AIN96408.1 - 2.7e-78 263.6 0.0 3.7e-78 263.2 0.0 1.2 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family AP_endonuc_2 PF01261.24 AIN96408.1 - 0.032 13.6 0.0 7.9 5.9 0.0 2.7 2 1 1 3 3 3 0 Xylose isomerase-like TIM barrel His_biosynth PF00977.21 AIN96408.1 - 0.059 12.8 0.0 0.1 12.1 0.0 1.4 1 0 0 1 1 1 0 Histidine biosynthesis protein Oxidored_FMN PF00724.20 AIN96409.1 - 1.6e-132 441.9 0.0 1.2e-74 251.7 0.0 2.1 2 0 0 2 2 2 2 NADH:flavin oxidoreductase / NADH oxidase family TmoB PF06234.12 AIN96409.1 - 0.11 12.7 0.6 6.7 6.9 0.2 2.7 2 0 0 2 2 2 0 Toluene-4-monooxygenase system protein B (TmoB) CSD PF00313.22 AIN96413.1 - 0.00048 19.9 0.0 0.0099 15.7 0.0 2.4 2 0 0 2 2 2 1 'Cold-shock' DNA-binding domain ABC_tran PF00005.27 AIN96414.1 - 6.7e-12 46.1 0.0 1.9e-05 25.2 0.0 2.5 2 0 0 2 2 2 2 ABC transporter AAA_30 PF13604.6 AIN96414.1 - 0.001 18.9 0.0 0.0025 17.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 AIN96414.1 - 0.0039 17.1 0.5 0.007 16.3 0.5 1.3 1 0 0 1 1 1 1 RsgA GTPase AAA_16 PF13191.6 AIN96414.1 - 0.033 14.6 0.6 0.13 12.6 0.6 2.0 1 0 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 AIN96414.1 - 0.054 13.8 0.1 0.48 10.7 0.1 2.5 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 AIN96414.1 - 0.057 13.2 0.2 0.13 12.0 0.2 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_21 PF13304.6 AIN96414.1 - 0.075 12.8 0.0 1.9 8.2 0.0 2.2 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_5 PF07728.14 AIN96414.1 - 0.21 11.6 0.1 0.53 10.3 0.1 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) ABC_ATPase PF09818.9 AIN96414.1 - 0.22 10.2 0.1 0.38 9.5 0.1 1.2 1 0 0 1 1 1 0 Predicted ATPase of the ABC class DUF3835 PF12927.7 AIN96415.1 - 0.04 14.8 0.1 0.089 13.7 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3835) Mcl1_mid PF12341.8 AIN96417.1 - 6.5e-56 189.9 0.0 9.8e-56 189.3 0.0 1.3 1 0 0 1 1 1 1 Minichromosome loss protein, Mcl1, middle region WD40 PF00400.32 AIN96417.1 - 0.074 14.0 2.4 15 6.6 0.1 4.5 4 0 0 4 4 4 0 WD domain, G-beta repeat DUF2121 PF09894.9 AIN96417.1 - 0.11 12.1 0.0 0.23 11.0 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2121) SNARE_assoc PF09335.11 AIN96418.1 - 5.1e-21 75.4 6.8 9.3e-21 74.5 6.4 1.7 2 0 0 2 2 2 1 SNARE associated Golgi protein 4HB_MCP_1 PF12729.7 AIN96418.1 - 0.18 11.4 0.0 0.32 10.5 0.0 1.3 1 0 0 1 1 1 0 Four helix bundle sensory module for signal transduction zf-RING_UBOX PF13445.6 AIN96419.1 - 1.1e-07 31.7 6.3 1.1e-07 31.7 6.3 2.3 3 0 0 3 3 3 1 RING-type zinc-finger zf-C3HC4 PF00097.25 AIN96419.1 - 1e-05 25.3 4.5 1e-05 25.3 4.5 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 AIN96419.1 - 6.8e-05 22.6 7.6 6.8e-05 22.6 7.6 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 AIN96419.1 - 0.00024 21.2 7.5 0.00024 21.2 7.5 2.7 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 AIN96419.1 - 0.0074 16.2 7.6 0.0074 16.2 7.6 2.7 3 0 0 3 3 3 1 zinc-RING finger domain RhoGEF PF00621.20 AIN96419.1 - 0.1 12.9 0.7 0.19 11.9 0.2 1.8 2 0 0 2 2 2 0 RhoGEF domain Peptidase_M1 PF01433.20 AIN96420.1 - 4.5e-48 163.7 0.0 7e-48 163.1 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M1 domain Peptidase_M1_N PF17900.1 AIN96420.1 - 8e-19 68.5 0.0 2.1e-14 54.1 0.0 2.2 2 0 0 2 2 2 2 Peptidase M1 N-terminal domain ERAP1_C PF11838.8 AIN96420.1 - 7.7e-07 29.0 0.0 1.3e-06 28.2 0.0 1.3 1 0 0 1 1 1 1 ERAP1-like C-terminal domain Aminopep PF10023.9 AIN96420.1 - 0.17 11.2 0.0 0.28 10.5 0.0 1.2 1 0 0 1 1 1 0 Putative aminopeptidase Prok-RING_2 PF14445.6 AIN96421.1 - 0.051 13.8 2.7 0.14 12.3 2.7 1.8 1 0 0 1 1 1 0 Prokaryotic RING finger family 2 FYVE PF01363.21 AIN96421.1 - 0.72 10.0 7.8 3.8 7.7 0.2 2.5 2 0 0 2 2 2 0 FYVE zinc finger PrmA PF06325.13 AIN96422.1 - 1.3e-12 47.7 0.0 2.1e-12 47.1 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_31 PF13847.6 AIN96422.1 - 2.9e-12 46.7 0.3 5.7e-12 45.7 0.3 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 AIN96422.1 - 4.7e-12 46.5 0.1 1.2e-11 45.2 0.1 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 AIN96422.1 - 1.2e-08 35.5 0.0 2.8e-08 34.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 AIN96422.1 - 2e-07 31.0 0.0 2.9e-07 30.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 AIN96422.1 - 7.9e-07 28.8 0.2 1.3e-06 28.1 0.2 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_9 PF08003.11 AIN96422.1 - 5.4e-06 25.6 0.0 7.5e-06 25.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_12 PF08242.12 AIN96422.1 - 9.8e-06 26.2 0.0 2e-05 25.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain TehB PF03848.14 AIN96422.1 - 1.6e-05 24.4 0.3 3.3e-05 23.4 0.3 1.5 1 1 0 1 1 1 1 Tellurite resistance protein TehB CMAS PF02353.20 AIN96422.1 - 2.4e-05 23.8 0.1 3.7e-05 23.1 0.1 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_18 PF12847.7 AIN96422.1 - 0.00013 21.9 0.1 0.00021 21.3 0.1 1.2 1 0 0 1 1 1 1 Methyltransferase domain PRMT5 PF05185.16 AIN96422.1 - 0.0007 19.5 0.0 0.0011 18.9 0.0 1.3 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase NodS PF05401.11 AIN96422.1 - 0.0054 16.4 0.1 0.0085 15.7 0.1 1.2 1 0 0 1 1 1 1 Nodulation protein S (NodS) Ubie_methyltran PF01209.18 AIN96422.1 - 0.0062 15.9 0.1 0.0099 15.2 0.1 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_32 PF13679.6 AIN96422.1 - 0.012 15.6 0.0 0.02 14.9 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain FtsJ PF01728.19 AIN96422.1 - 0.016 15.3 0.0 0.025 14.7 0.0 1.5 1 1 0 1 1 1 0 FtsJ-like methyltransferase PCMT PF01135.19 AIN96422.1 - 0.03 14.1 0.0 0.044 13.5 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_24 PF13578.6 AIN96422.1 - 0.034 15.2 0.0 0.07 14.2 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Met_10 PF02475.16 AIN96422.1 - 0.055 13.2 0.0 0.084 12.6 0.0 1.2 1 0 0 1 1 1 0 Met-10+ like-protein SET PF00856.28 AIN96425.1 - 1.1e-09 38.8 0.0 2.2e-09 37.9 0.0 1.5 1 0 0 1 1 1 1 SET domain zf-MYND PF01753.18 AIN96425.1 - 2.1e-05 24.5 6.1 2.1e-05 24.5 6.1 2.7 2 0 0 2 2 2 1 MYND finger TPR_1 PF00515.28 AIN96425.1 - 0.0087 15.9 0.3 2.5 8.1 0.2 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.17 AIN96425.1 - 0.01 15.9 0.1 0.18 12.0 0.3 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.6 AIN96425.1 - 0.067 13.5 0.4 0.23 11.8 0.4 2.0 1 1 0 1 1 1 0 Tetratricopeptide repeat RNase_H2_suC PF08615.11 AIN96426.1 - 3e-10 40.4 0.0 4.3e-10 39.9 0.0 1.3 1 1 0 1 1 1 1 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) FAM91_C PF14648.6 AIN96427.1 - 8.5e-117 390.6 0.0 1.4e-114 383.3 0.0 2.1 1 1 0 1 1 1 1 FAM91 C-terminus FAM91_N PF14647.6 AIN96427.1 - 1.1e-99 333.7 0.1 1.6e-99 333.1 0.1 1.2 1 0 0 1 1 1 1 FAM91 N-terminus Vps39_2 PF10367.9 AIN96428.1 - 1.6e-25 89.6 0.6 4.1e-25 88.3 0.6 1.7 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 Vps39_1 PF10366.9 AIN96428.1 - 3.6e-06 27.2 0.1 2.8e-05 24.4 0.1 2.4 2 0 0 2 2 2 1 Vacuolar sorting protein 39 domain 1 CNH PF00780.22 AIN96428.1 - 5.9e-06 26.1 0.0 1e-05 25.3 0.0 1.3 1 0 0 1 1 1 1 CNH domain Clathrin PF00637.20 AIN96428.1 - 0.00022 21.1 0.0 0.016 15.1 0.0 2.6 2 1 0 2 2 2 1 Region in Clathrin and VPS Rad50_zn_hook PF04423.14 AIN96428.1 - 0.11 12.4 0.4 0.36 10.7 0.0 1.9 2 0 0 2 2 2 0 Rad50 zinc hook motif Baculo_LEF5_C PF11792.8 AIN96428.1 - 0.14 11.9 0.0 0.93 9.2 0.0 2.4 2 0 0 2 2 2 0 Baculoviridae late expression factor 5 C-terminal domain Abhydrolase_1 PF00561.20 AIN96429.1 - 0.00054 19.7 0.2 0.0029 17.3 0.0 2.2 2 1 1 3 3 3 1 alpha/beta hydrolase fold DLH PF01738.18 AIN96429.1 - 0.03 13.9 0.1 0.1 12.1 0.0 1.8 2 0 0 2 2 2 0 Dienelactone hydrolase family Peptidase_S9 PF00326.21 AIN96429.1 - 0.031 13.7 0.0 0.055 12.9 0.0 1.4 1 0 0 1 1 1 0 Prolyl oligopeptidase family Rep_trans PF02486.19 AIN96430.1 - 0.056 13.2 0.0 0.088 12.5 0.0 1.3 1 0 0 1 1 1 0 Replication initiation factor Methyltransf_16 PF10294.9 AIN96431.1 - 3.8e-11 43.0 0.1 9.8e-11 41.7 0.1 1.6 1 1 0 1 1 1 1 Lysine methyltransferase Methyltransf_23 PF13489.6 AIN96431.1 - 0.0019 18.1 0.0 0.0034 17.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 AIN96431.1 - 0.0059 17.3 0.3 0.039 14.6 0.3 2.2 1 1 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 AIN96431.1 - 0.01 15.3 0.5 0.025 14.0 0.1 1.7 2 0 0 2 2 2 0 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 AIN96431.1 - 0.02 14.5 0.4 0.31 10.6 0.4 2.4 1 1 0 1 1 1 0 Methyltransferase small domain HECT_2 PF09814.9 AIN96431.1 - 0.099 11.5 0.2 0.14 11.0 0.2 1.2 1 0 0 1 1 1 0 HECT-like Ubiquitin-conjugating enzyme (E2)-binding WD40 PF00400.32 AIN96432.1 - 1.6e-10 41.4 5.1 0.19 12.6 0.4 5.9 6 0 0 6 6 6 4 WD domain, G-beta repeat Nup160 PF11715.8 AIN96432.1 - 0.026 13.2 0.0 0.12 10.9 0.0 2.0 1 1 0 1 1 1 0 Nucleoporin Nup120/160 PQQ PF01011.21 AIN96432.1 - 0.12 12.3 0.4 0.92 9.5 0.1 2.4 2 0 0 2 2 2 0 PQQ enzyme repeat Prenyltransf PF01255.19 AIN96433.1 - 1.7e-56 191.2 0.2 1.9e-52 178.0 0.0 2.3 2 0 0 2 2 2 2 Putative undecaprenyl diphosphate synthase CLZ PF16526.5 AIN96434.1 - 0.029 14.7 1.0 0.47 10.8 0.5 2.3 1 1 1 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels DUF3086 PF11285.8 AIN96434.1 - 0.072 12.2 0.3 0.092 11.8 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3086) SKA2 PF16740.5 AIN96434.1 - 0.086 12.6 0.3 1.1 9.1 0.0 2.2 1 1 1 2 2 2 0 Spindle and kinetochore-associated protein 2 RNase_HII PF01351.18 AIN96436.1 - 1.4e-14 54.4 0.0 9e-11 42.0 0.0 2.2 2 0 0 2 2 2 2 Ribonuclease HII DNA_pol_A PF00476.20 AIN96438.1 - 3.4e-34 118.5 0.0 1.1e-33 116.9 0.0 1.7 1 1 0 1 1 1 1 DNA polymerase family A RNase_T PF00929.24 AIN96438.1 - 1.2e-15 58.5 0.0 6.4e-15 56.1 0.0 2.4 2 1 0 2 2 2 1 Exonuclease Pro_dh PF01619.18 AIN96438.1 - 0.0083 15.7 0.0 0.021 14.4 0.0 1.6 1 0 0 1 1 1 1 Proline dehydrogenase RNase_H_2 PF13482.6 AIN96438.1 - 0.011 15.7 0.0 0.043 13.8 0.0 2.0 2 0 0 2 2 2 0 RNase_H superfamily Peptidase_M32 PF02074.15 AIN96439.1 - 1.1e-154 515.9 0.0 1.2e-154 515.7 0.0 1.0 1 0 0 1 1 1 1 Carboxypeptidase Taq (M32) metallopeptidase DUF5347 PF17282.2 AIN96440.1 - 0.099 12.9 0.0 0.18 12.1 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5347) AMA-1 PF02430.15 AIN96440.1 - 0.1 11.6 0.0 0.14 11.1 0.0 1.1 1 0 0 1 1 1 0 Apical membrane antigen 1 SURF1 PF02104.15 AIN96441.1 - 2e-30 106.3 0.2 3.3e-30 105.6 0.0 1.4 2 0 0 2 2 2 1 SURF1 family DUF1471 PF07338.13 AIN96441.1 - 0.061 13.3 0.1 0.14 12.1 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1471) Atg14 PF10186.9 AIN96442.1 - 0.0022 17.1 6.3 0.0024 17.0 6.3 1.0 1 0 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 Troponin PF00992.20 AIN96442.1 - 0.014 15.7 5.6 0.016 15.5 5.6 1.2 1 0 0 1 1 1 0 Troponin Jnk-SapK_ap_N PF09744.9 AIN96442.1 - 0.023 14.9 9.1 0.026 14.8 9.1 1.1 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 Vmethyltransf PF01660.17 AIN96442.1 - 0.044 12.7 0.4 0.051 12.4 0.4 1.1 1 0 0 1 1 1 0 Viral methyltransferase CCDC92 PF14916.6 AIN96442.1 - 0.047 13.5 6.5 0.11 12.3 0.2 2.6 2 1 0 2 2 2 0 Coiled-coil domain of unknown function TMPIT PF07851.13 AIN96442.1 - 0.047 12.9 3.2 0.052 12.8 3.2 1.0 1 0 0 1 1 1 0 TMPIT-like protein TPR_MLP1_2 PF07926.12 AIN96442.1 - 0.27 11.3 11.7 0.74 9.9 11.7 1.6 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein Herpes_UL6 PF01763.16 AIN96442.1 - 0.43 9.0 3.5 0.48 8.9 3.5 1.1 1 0 0 1 1 1 0 Herpesvirus UL6 like DUF4337 PF14235.6 AIN96442.1 - 0.5 10.5 2.7 0.59 10.2 2.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) PV-1 PF06637.11 AIN96442.1 - 0.79 8.5 7.0 0.93 8.2 7.0 1.0 1 0 0 1 1 1 0 PV-1 protein (PLVAP) ResIII PF04851.15 AIN96442.1 - 1.5 8.8 3.9 7.9 6.4 3.9 1.9 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit YabA PF06156.13 AIN96442.1 - 2 9.1 7.7 25 5.6 7.9 2.1 1 1 0 1 1 1 0 Initiation control protein YabA APG6_N PF17675.1 AIN96442.1 - 4.9 7.7 16.3 25 5.4 0.1 2.0 1 1 1 2 2 2 0 Apg6 coiled-coil region Kinesin PF00225.23 AIN96443.1 - 9e-88 294.4 0.2 1.2e-87 294.0 0.2 1.1 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 AIN96443.1 - 2.1e-15 56.9 0.0 5.1e-15 55.7 0.0 1.6 1 0 0 1 1 1 1 Microtubule binding zf-TRAF PF02176.18 AIN96443.1 - 2.1e-13 50.7 44.4 1.1e-06 29.2 4.8 5.3 4 1 2 6 6 6 4 TRAF-type zinc finger AAA_22 PF13401.6 AIN96443.1 - 0.042 14.1 0.3 0.13 12.5 0.1 1.9 2 0 0 2 2 2 0 AAA domain zf-TRAF_2 PF15965.5 AIN96443.1 - 0.064 13.7 0.0 0.064 13.7 0.0 4.5 3 1 1 4 4 4 0 TRAF-like zinc-finger PRP21_like_P PF12230.8 AIN96443.1 - 1.8 8.4 4.1 14 5.5 0.4 3.1 1 1 2 3 3 3 0 Pre-mRNA splicing factor PRP21 like protein PHD_4 PF16866.5 AIN96443.1 - 3.6 7.7 20.9 6.4 7.0 2.8 3.4 1 1 1 2 2 2 0 PHD-finger PyrI_C PF02748.15 AIN96443.1 - 8.1 6.4 12.6 6.6 6.7 0.4 3.7 3 0 0 3 3 3 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain PhyH PF05721.13 AIN96445.1 - 0.072 13.3 0.0 13 6.0 0.0 2.7 2 1 0 2 2 2 0 Phytanoyl-CoA dioxygenase (PhyH) cNMP_binding PF00027.29 AIN96446.1 - 2.9e-31 107.4 0.4 1e-17 63.9 0.0 2.5 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain DUF333 PF03891.15 AIN96446.1 - 0.11 12.7 0.0 0.25 11.6 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF333) MOZ_SAS PF01853.18 AIN96447.1 - 8.9e-21 74.3 0.0 1.6e-11 44.2 0.0 2.3 2 0 0 2 2 2 2 MOZ/SAS family zf-MYST PF17772.1 AIN96447.1 - 0.0013 18.3 2.5 0.0013 18.3 2.5 1.9 2 0 0 2 2 2 1 MYST family zinc finger domain TPR_12 PF13424.6 AIN96448.1 - 4.5e-11 42.9 15.6 2.4e-07 30.9 0.2 4.4 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 AIN96448.1 - 1e-06 28.4 4.1 0.5 10.6 0.0 4.7 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_6 PF13174.6 AIN96448.1 - 0.012 16.2 3.6 10 7.0 0.0 5.0 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_8 PF13181.6 AIN96448.1 - 0.018 15.2 0.6 90 3.7 0.0 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.28 AIN96448.1 - 0.05 13.4 0.3 8 6.5 0.0 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_10 PF13374.6 AIN96448.1 - 0.14 12.1 16.1 5.2 7.1 0.0 5.5 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_16 PF13432.6 AIN96448.1 - 2 9.1 10.0 3.4 8.4 0.0 3.9 3 1 0 3 3 3 0 Tetratricopeptide repeat cNMPbd_u2 PF16643.5 AIN96449.1 - 0.052 14.0 0.0 0.052 14.0 0.0 2.1 2 1 0 2 2 2 0 Unstructured region on cNMP-binding protein Lipase_3 PF01764.25 AIN96450.1 - 7.2e-14 51.8 0.0 1.4e-13 50.9 0.0 1.5 1 0 0 1 1 1 1 Lipase (class 3) Lipase_3 PF01764.25 AIN96451.1 - 4.8e-14 52.4 0.0 1.1e-13 51.3 0.0 1.6 1 0 0 1 1 1 1 Lipase (class 3) UPF0227 PF05728.12 AIN96451.1 - 0.15 12.0 0.0 0.29 11.1 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) Adeno_PV PF03910.13 AIN96451.1 - 2.8 6.6 5.1 6.3 5.4 5.1 1.6 1 0 0 1 1 1 0 Adenovirus minor core protein PV Ras PF00071.22 AIN96452.1 - 1.7e-51 174.0 0.0 2.1e-51 173.8 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 AIN96452.1 - 2.7e-33 114.7 0.0 4e-33 114.2 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 AIN96452.1 - 3.6e-12 46.1 0.0 5.1e-12 45.6 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 AIN96452.1 - 3.2e-07 29.9 0.0 4.2e-07 29.6 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 AIN96452.1 - 2.1e-06 27.7 0.1 0.0041 17.0 0.1 2.2 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 AIN96452.1 - 7.1e-06 26.1 0.0 1.2e-05 25.4 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 AIN96452.1 - 3.2e-05 24.4 0.1 4e-05 24.1 0.1 1.3 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 AIN96452.1 - 0.0021 18.3 0.0 0.0043 17.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain GTP_EFTU PF00009.27 AIN96452.1 - 0.0038 16.8 0.0 0.02 14.4 0.0 1.9 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain AAA_5 PF07728.14 AIN96452.1 - 0.013 15.4 0.0 0.023 14.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) NACHT PF05729.12 AIN96452.1 - 0.015 15.2 0.0 0.025 14.5 0.0 1.3 1 0 0 1 1 1 0 NACHT domain AAA_7 PF12775.7 AIN96452.1 - 0.016 14.8 0.0 0.026 14.0 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_24 PF13479.6 AIN96452.1 - 0.023 14.4 0.0 0.1 12.3 0.0 1.9 2 0 0 2 2 2 0 AAA domain TsaE PF02367.17 AIN96452.1 - 0.027 14.5 0.0 0.047 13.7 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE G-alpha PF00503.20 AIN96452.1 - 0.051 12.7 0.3 0.46 9.6 0.1 2.1 1 1 1 2 2 2 0 G-protein alpha subunit ABC_tran PF00005.27 AIN96452.1 - 0.071 13.6 0.0 0.16 12.5 0.0 1.5 1 0 0 1 1 1 0 ABC transporter RNA_helicase PF00910.22 AIN96452.1 - 0.081 13.3 0.0 0.15 12.4 0.0 1.5 1 0 0 1 1 1 0 RNA helicase Sigma54_activat PF00158.26 AIN96452.1 - 0.13 12.0 0.0 0.21 11.2 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_18 PF13238.6 AIN96452.1 - 0.15 12.6 0.1 0.86 10.1 0.0 2.0 1 1 1 2 2 2 0 AAA domain SRPRB PF09439.10 AIN96452.1 - 0.2 11.1 0.0 0.26 10.7 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit zf-C3HC4_3 PF13920.6 AIN96453.1 - 5e-06 26.3 8.6 1.1e-05 25.2 8.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 AIN96453.1 - 3.4e-05 23.7 8.4 6.9e-05 22.7 8.4 1.5 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 AIN96453.1 - 0.0026 17.6 9.3 0.0053 16.6 9.3 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 AIN96453.1 - 0.01 15.7 9.1 0.021 14.6 9.1 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 AIN96453.1 - 0.011 16.0 9.7 0.022 15.1 9.7 1.5 1 0 0 1 1 1 0 Ring finger domain ERM PF00769.19 AIN96453.1 - 0.022 14.6 3.4 0.031 14.1 3.4 1.1 1 0 0 1 1 1 0 Ezrin/radixin/moesin family zf-C3HC4 PF00097.25 AIN96453.1 - 0.039 13.8 7.8 0.077 12.9 7.8 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Gin PF10764.9 AIN96453.1 - 0.068 13.1 0.8 0.12 12.3 0.8 1.4 1 0 0 1 1 1 0 Inhibitor of sigma-G Gin DASH_Dad2 PF08654.10 AIN96453.1 - 0.071 13.5 0.7 0.13 12.7 0.7 1.4 1 0 0 1 1 1 0 DASH complex subunit Dad2 TP_methylase PF00590.20 AIN96453.1 - 0.1 12.5 1.2 0.17 11.8 1.2 1.3 1 0 0 1 1 1 0 Tetrapyrrole (Corrin/Porphyrin) Methylases DUF1192 PF06698.11 AIN96453.1 - 0.12 12.5 0.3 0.38 10.8 0.3 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF1192) GAS PF13851.6 AIN96453.1 - 0.13 11.6 2.3 0.2 11.0 2.3 1.3 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding DUF1848 PF08902.11 AIN96453.1 - 0.16 11.6 0.6 0.24 11.1 0.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1848) zf-P11 PF03854.14 AIN96453.1 - 0.17 11.6 7.6 0.35 10.6 7.6 1.5 1 0 0 1 1 1 0 P-11 zinc finger zf-RING_4 PF14570.6 AIN96453.1 - 0.25 11.2 8.7 0.45 10.4 8.7 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain SlyX PF04102.12 AIN96453.1 - 7.9 7.2 10.9 60 4.4 5.7 2.9 2 1 1 3 3 3 0 SlyX DUF4200 PF13863.6 AIN96454.1 - 3.8e-23 82.1 21.6 3.8e-23 82.1 21.6 3.3 3 1 0 3 3 3 1 Domain of unknown function (DUF4200) Ribonuc_red_2_N PF08471.10 AIN96454.1 - 0.043 14.0 3.7 0.12 12.6 3.5 1.9 1 1 0 1 1 1 0 Class II vitamin B12-dependent ribonucleotide reductase DUF3918 PF13056.6 AIN96454.1 - 0.18 11.5 0.2 0.18 11.5 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3918) AsnC_trans_reg PF01037.21 AIN96454.1 - 0.21 11.6 1.0 0.84 9.6 0.0 2.4 3 0 0 3 3 3 0 Lrp/AsnC ligand binding domain HTH_26 PF13443.6 AIN96454.1 - 0.97 9.9 3.9 2.6 8.5 0.6 2.6 2 0 0 2 2 2 0 Cro/C1-type HTH DNA-binding domain MCD_N PF17408.2 AIN96454.1 - 1.8 8.8 6.8 0.33 11.1 2.2 2.3 2 2 0 2 2 2 0 Malonyl-CoA decarboxylase N-terminal domain KMP11 PF03037.16 AIN96454.1 - 2.4 9.0 10.9 6.7 7.6 0.9 3.1 4 0 0 4 4 4 0 Kinetoplastid membrane protein 11 TACC_C PF05010.14 AIN96454.1 - 2.7 7.7 31.8 0.75 9.6 27.2 2.2 2 1 0 2 2 2 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal AATF-Che1 PF13339.6 AIN96454.1 - 5 7.8 23.3 0.66 10.7 5.9 3.2 2 1 0 3 3 3 0 Apoptosis antagonizing transcription factor ANAPC4_WD40 PF12894.7 AIN96455.1 - 0.036 14.4 0.1 3.8 7.9 0.1 3.1 2 1 1 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain Acetyltransf_1 PF00583.25 AIN96456.1 - 2.5e-13 50.3 0.2 4.7e-13 49.4 0.0 1.5 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family FR47 PF08445.10 AIN96456.1 - 2e-07 30.9 0.0 3.2e-07 30.2 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.7 AIN96456.1 - 4.1e-07 30.0 0.2 8.4e-07 29.0 0.2 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 AIN96456.1 - 1e-05 25.8 0.1 2.3e-05 24.7 0.1 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_15 PF17013.5 AIN96456.1 - 0.0022 17.5 0.3 0.0026 17.3 0.3 1.2 1 0 0 1 1 1 1 Putative acetyl-transferase Acetyltransf_4 PF13420.7 AIN96456.1 - 0.009 16.2 0.4 0.014 15.5 0.4 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain DUF5596 PF18082.1 AIN96456.1 - 0.022 14.6 0.1 0.053 13.3 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF5596) Acetyltransf_9 PF13527.7 AIN96456.1 - 0.053 13.6 0.2 0.053 13.6 0.2 1.7 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Tubulin PF00091.25 AIN96458.1 - 7.3e-65 218.9 0.0 9.8e-65 218.4 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 AIN96458.1 - 4e-50 169.2 0.0 6.7e-50 168.5 0.0 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 AIN96458.1 - 0.0073 16.0 0.0 0.016 14.9 0.0 1.6 1 0 0 1 1 1 1 Tubulin domain Nipped-B_C PF12830.7 AIN96459.1 - 2.5e-25 89.6 0.3 2e-24 86.6 0.1 2.5 2 0 0 2 2 2 1 Sister chromatid cohesion C-terminus NODP PF07684.12 AIN96459.1 - 0.034 14.3 0.1 0.14 12.3 0.1 2.1 1 0 0 1 1 1 0 NOTCH protein Nitrate_red_gam PF02665.14 AIN96459.1 - 0.061 12.9 0.0 0.17 11.4 0.0 1.6 1 0 0 1 1 1 0 Nitrate reductase gamma subunit Tcp11 PF05794.13 AIN96459.1 - 0.62 9.1 4.7 9.8 5.1 2.1 3.3 2 1 0 2 2 2 0 T-complex protein 11 HEAT PF02985.22 AIN96459.1 - 1.4 9.4 4.5 25 5.5 0.1 4.8 4 0 0 4 4 4 0 HEAT repeat AMP-binding PF00501.28 AIN96461.1 - 2.2e-61 207.7 0.2 2.9e-61 207.3 0.2 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 AIN96461.1 - 0.0017 19.3 0.1 0.0093 16.9 0.1 2.4 1 1 0 1 1 1 1 AMP-binding enzyme C-terminal domain FeoA PF04023.14 AIN96461.1 - 0.043 14.1 0.0 0.15 12.3 0.0 1.9 1 0 0 1 1 1 0 FeoA domain Radial_spoke PF04712.12 AIN96462.1 - 2.1e-119 399.7 16.3 2.7e-87 293.8 5.5 2.7 1 1 1 2 2 2 2 Radial spokehead-like protein eIF-3c_N PF05470.12 AIN96462.1 - 3.9 5.7 5.4 7.4 4.7 5.4 1.4 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus Pkinase PF00069.25 AIN96463.1 - 6.7e-80 268.2 0.0 1.2e-79 267.4 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 AIN96463.1 - 2.4e-45 154.8 0.0 4.2e-45 154.1 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase HEAT_EZ PF13513.6 AIN96463.1 - 5.1e-09 36.4 4.9 0.00031 21.2 0.2 5.1 4 1 1 5 5 5 2 HEAT-like repeat Arm PF00514.23 AIN96463.1 - 3e-08 33.4 6.7 0.0014 18.6 0.1 6.5 6 0 0 6 6 6 1 Armadillo/beta-catenin-like repeat Kinase-like PF14531.6 AIN96463.1 - 8.6e-06 25.3 0.0 0.00013 21.4 0.0 2.1 1 1 1 2 2 2 1 Kinase-like HEAT_2 PF13646.6 AIN96463.1 - 2.7e-05 24.5 0.1 0.00042 20.6 0.1 2.9 1 1 1 2 2 2 2 HEAT repeats Pkinase_fungal PF17667.1 AIN96463.1 - 7.4e-05 21.7 0.0 0.00018 20.4 0.0 1.6 1 0 0 1 1 1 1 Fungal protein kinase HEAT PF02985.22 AIN96463.1 - 0.00015 21.7 2.8 2.8 8.4 0.0 5.5 4 0 0 4 4 4 1 HEAT repeat RIO1 PF01163.22 AIN96463.1 - 0.00021 21.0 1.1 0.0036 16.9 0.1 2.3 1 1 0 2 2 2 1 RIO1 family FTA2 PF13095.6 AIN96463.1 - 0.0021 17.7 1.4 0.34 10.5 0.1 2.4 1 1 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 Haspin_kinase PF12330.8 AIN96463.1 - 0.0048 15.9 0.1 0.0093 14.9 0.1 1.4 1 0 0 1 1 1 1 Haspin like kinase domain YrbL-PhoP_reg PF10707.9 AIN96463.1 - 0.0052 16.3 0.1 0.011 15.2 0.1 1.5 1 0 0 1 1 1 1 PhoP regulatory network protein YrbL APH PF01636.23 AIN96463.1 - 0.0079 16.1 0.0 0.024 14.5 0.0 1.8 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 AIN96463.1 - 0.011 15.1 0.0 0.022 14.1 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.11 AIN96463.1 - 0.014 14.5 0.0 0.033 13.3 0.0 1.5 1 0 0 1 1 1 0 Seadornavirus VP7 Urb2 PF10441.9 AIN96463.1 - 0.016 15.2 0.1 0.085 12.8 0.0 2.3 2 0 0 2 2 2 0 Urb2/Npa2 family ABC1 PF03109.16 AIN96463.1 - 0.032 14.4 0.1 0.25 11.5 0.0 2.3 1 1 1 2 2 2 0 ABC1 family WAPL PF07814.13 AIN96463.1 - 0.047 12.5 0.7 0.25 10.1 0.2 2.4 2 0 0 2 2 2 0 Wings apart-like protein regulation of heterochromatin PIP49_C PF12260.8 AIN96463.1 - 0.11 12.1 0.0 0.29 10.7 0.0 1.6 1 0 0 1 1 1 0 Protein-kinase domain of FAM69 Alba PF01918.21 AIN96464.1 - 4.2e-15 55.3 0.3 7.1e-15 54.6 0.3 1.3 1 0 0 1 1 1 1 Alba Rpp20 PF12328.8 AIN96464.1 - 0.0014 18.6 0.6 0.0016 18.4 0.6 1.1 1 0 0 1 1 1 1 Rpp20 subunit of nuclear RNase MRP and P AlphaC_N PF08829.10 AIN96464.1 - 0.0084 16.1 0.0 0.012 15.7 0.0 1.3 1 0 0 1 1 1 1 Alpha C protein N terminal Phage_ABA_S PF18066.1 AIN96464.1 - 0.093 13.4 0.0 0.14 12.9 0.0 1.5 1 1 0 1 1 1 0 Phage ABA sandwich domain C2 PF00168.30 AIN96465.1 - 0.0031 17.8 0.1 0.0093 16.2 0.0 1.8 2 0 0 2 2 2 1 C2 domain Maf PF02545.14 AIN96465.1 - 0.19 11.6 0.0 0.34 10.7 0.0 1.3 1 0 0 1 1 1 0 Maf-like protein CENP-F_leu_zip PF10473.9 AIN96466.1 - 5e-09 36.3 54.6 0.0023 17.9 14.6 6.1 3 2 3 6 6 6 6 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 TMF_TATA_bd PF12325.8 AIN96466.1 - 4e-06 27.0 55.0 2.4e-05 24.5 2.4 5.2 2 1 3 5 5 5 2 TATA element modulatory factor 1 TATA binding DUF2353 PF09789.9 AIN96466.1 - 3.5e-05 23.3 41.0 0.0031 16.9 20.0 4.3 2 1 2 5 5 5 3 Uncharacterized coiled-coil protein (DUF2353) Spc7 PF08317.11 AIN96466.1 - 0.0005 19.0 15.9 0.0005 19.0 15.9 3.1 2 1 2 4 4 4 1 Spc7 kinetochore protein Filament PF00038.21 AIN96466.1 - 0.0014 18.2 53.1 0.015 14.9 9.0 5.1 2 1 4 6 6 6 3 Intermediate filament protein BCL_N PF04714.13 AIN96466.1 - 0.0034 17.4 6.4 0.12 12.4 0.0 3.8 3 0 0 3 3 3 1 BCL7, N-terminal conserver region Uso1_p115_C PF04871.13 AIN96466.1 - 0.0057 17.0 55.0 0.02 15.3 0.7 5.3 2 1 3 5 5 5 1 Uso1 / p115 like vesicle tethering protein, C terminal region GAS PF13851.6 AIN96466.1 - 0.054 12.8 54.4 0.31 10.4 1.4 4.8 2 1 3 5 5 5 0 Growth-arrest specific micro-tubule binding DUF4407 PF14362.6 AIN96466.1 - 0.078 12.3 44.2 0.021 14.2 15.2 3.7 2 1 2 4 4 4 0 Domain of unknown function (DUF4407) BST2 PF16716.5 AIN96466.1 - 0.09 13.4 50.2 0.056 14.0 3.0 6.4 3 2 1 6 6 6 0 Bone marrow stromal antigen 2 NPV_P10 PF05531.12 AIN96466.1 - 0.11 13.0 20.0 2 8.9 0.4 5.7 4 1 0 4 4 4 0 Nucleopolyhedrovirus P10 protein Fez1 PF06818.15 AIN96466.1 - 0.15 12.5 49.3 28 5.1 18.6 4.3 1 1 2 3 3 3 0 Fez1 Fib_alpha PF08702.10 AIN96466.1 - 0.35 11.1 36.5 0.079 13.1 3.5 4.9 2 1 3 5 5 5 0 Fibrinogen alpha/beta chain family IFP_35_N PF07334.13 AIN96466.1 - 0.92 9.6 13.9 4.1 7.5 1.3 5.2 4 1 0 4 4 4 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus THP2 PF09432.10 AIN96466.1 - 1.1 9.3 19.9 0.84 9.7 1.7 3.7 2 2 1 3 3 3 0 Tho complex subunit THP2 V_ATPase_I PF01496.19 AIN96466.1 - 1.1 7.1 22.3 22 2.8 19.9 2.6 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF1664 PF07889.12 AIN96466.1 - 2.1 8.4 29.0 1.1 9.3 1.6 5.5 2 1 3 6 6 6 0 Protein of unknown function (DUF1664) LPP PF04728.13 AIN96466.1 - 2.3 8.7 20.4 1.1 9.7 2.4 6.0 6 0 0 6 6 6 0 Lipoprotein leucine-zipper Rootletin PF15035.6 AIN96466.1 - 5.5 7.0 60.8 1.4 8.9 4.3 5.6 2 1 3 5 5 5 0 Ciliary rootlet component, centrosome cohesion Leu_zip PF15294.6 AIN96466.1 - 6.1 6.3 40.3 0.19 11.2 3.0 3.9 2 1 2 4 4 4 0 Leucine zipper Seryl_tRNA_N PF02403.22 AIN96466.1 - 7.5 6.8 37.0 0.23 11.7 6.8 5.0 2 1 1 4 4 4 0 Seryl-tRNA synthetase N-terminal domain DUF573 PF04504.14 AIN96466.1 - 7.6 7.3 11.0 2.7 8.7 0.8 3.3 3 2 1 4 4 3 0 Protein of unknown function, DUF573 FlaC_arch PF05377.11 AIN96466.1 - 7.9 7.0 29.8 1.5 9.3 0.2 7.7 5 3 3 8 8 8 0 Flagella accessory protein C (FlaC) His_Phos_1 PF00300.22 AIN96467.1 - 2.1e-08 34.1 0.0 1.3e-05 25.0 0.0 2.8 2 1 0 2 2 2 2 Histidine phosphatase superfamily (branch 1) Sec63 PF02889.16 AIN96468.1 - 9e-143 474.0 3.3 1.3e-80 270.3 1.4 2.5 2 0 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.29 AIN96468.1 - 1.3e-52 178.2 0.0 6.2e-28 97.7 0.1 2.7 2 0 0 2 2 2 2 DEAD/DEAH box helicase ResIII PF04851.15 AIN96468.1 - 1.4e-28 100.1 0.0 1.1e-16 61.3 0.0 2.4 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit Helicase_C PF00271.31 AIN96468.1 - 1.1e-15 58.0 0.0 4.4e-07 30.2 0.0 4.0 2 2 0 2 2 2 2 Helicase conserved C-terminal domain AAA_30 PF13604.6 AIN96468.1 - 4.1e-10 39.7 0.0 8.6e-05 22.3 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.6 AIN96468.1 - 1.3e-06 28.8 2.9 0.00071 19.9 0.1 3.2 3 0 0 3 3 3 2 AAA domain AAA_22 PF13401.6 AIN96468.1 - 7.1e-06 26.3 1.3 0.0022 18.3 0.0 3.6 3 2 0 3 3 2 1 AAA domain T2SSE PF00437.20 AIN96468.1 - 0.00024 20.2 0.0 0.64 9.0 0.0 2.6 2 0 0 2 2 2 2 Type II/IV secretion system protein SWI2_SNF2 PF18766.1 AIN96468.1 - 0.00058 19.6 0.2 0.043 13.5 0.1 2.3 2 0 0 2 2 2 1 SWI2/SNF2 ATPase PhoH PF02562.16 AIN96468.1 - 0.00081 18.9 0.1 0.13 11.7 0.0 2.3 2 0 0 2 2 2 1 PhoH-like protein DUF2075 PF09848.9 AIN96468.1 - 0.001 18.4 0.0 0.003 16.8 0.0 1.8 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) SpuA_C PF18033.1 AIN96468.1 - 0.0016 18.4 0.4 0.92 9.6 0.1 3.1 2 0 0 2 2 2 1 SpuA C-terminal AAA_7 PF12775.7 AIN96468.1 - 0.01 15.3 0.2 1.4 8.4 0.1 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region TniB PF05621.11 AIN96468.1 - 0.03 13.7 0.1 1.8 8.0 0.0 3.2 3 0 0 3 3 3 0 Bacterial TniB protein UvrD-helicase PF00580.21 AIN96468.1 - 0.057 12.9 0.7 2.6 7.5 0.0 2.6 3 0 0 3 3 3 0 UvrD/REP helicase N-terminal domain AAA PF00004.29 AIN96468.1 - 0.063 13.7 1.2 5 7.6 0.2 3.8 3 2 0 3 3 2 0 ATPase family associated with various cellular activities (AAA) IstB_IS21 PF01695.17 AIN96468.1 - 0.064 13.0 0.0 17 5.1 0.0 2.9 3 0 0 3 3 3 0 IstB-like ATP binding protein Phage_TAC_11 PF11836.8 AIN96469.1 - 0.096 12.8 0.1 0.2 11.8 0.1 1.5 1 0 0 1 1 1 0 Phage tail tube protein, GTA-gp10 Ccdc124 PF06244.12 AIN96470.1 - 5.5e-24 85.1 20.9 1.4e-22 80.6 20.9 2.4 1 1 0 1 1 1 1 Coiled-coil domain-containing protein 124 /Oxs1 HMG_box PF00505.19 AIN96470.1 - 0.048 14.1 0.5 0.048 14.1 0.5 3.2 2 1 1 3 3 3 0 HMG (high mobility group) box DUF3435 PF11917.8 AIN96470.1 - 0.18 10.7 11.7 0.27 10.1 11.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3435) COG2 PF06148.11 AIN96470.1 - 5.7 7.0 11.5 8.4 6.5 8.6 2.2 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 V_ATPase_I PF01496.19 AIN96470.1 - 7.9 4.3 7.6 8.7 4.1 7.6 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family PDZ_assoc PF10600.9 AIN96471.1 - 0.32 11.9 5.5 5.6 7.9 4.8 3.0 2 0 0 2 2 2 0 PDZ-associated domain of NMDA receptors AvrLm4-7 PF18661.1 AIN96471.1 - 0.72 10.9 0.1 0.72 10.9 0.1 2.5 3 0 0 3 3 3 0 Avirulence Effector AvrLm4-7 DUF179 PF02622.15 AIN96473.1 - 6.2e-19 68.5 0.0 1.2e-18 67.6 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized ACR, COG1678 Ribosomal_L18 PF17135.4 AIN96474.1 - 3.9e-74 248.1 3.1 4.6e-74 247.9 3.1 1.0 1 0 0 1 1 1 1 Ribosomal protein 60S L18 and 50S L18e Ribosomal_L27A PF00828.19 AIN96474.1 - 0.00071 20.2 0.1 0.002 18.8 0.1 1.9 1 1 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A Ribosomal_L7Ae PF01248.26 AIN96475.1 - 4.3e-22 77.7 1.0 6.1e-22 77.2 1.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family SpoU_sub_bind PF08032.12 AIN96475.1 - 0.13 12.5 0.1 0.49 10.7 0.0 1.9 2 0 0 2 2 2 0 RNA 2'-O ribose methyltransferase substrate binding ZapB PF06005.12 AIN96476.1 - 0.02 15.3 0.2 0.06 13.8 0.2 1.8 1 0 0 1 1 1 0 Cell division protein ZapB Atg14 PF10186.9 AIN96476.1 - 0.12 11.5 4.2 4.2 6.4 0.2 2.2 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 MCU PF04678.13 AIN96478.1 - 2e-10 41.1 0.1 2.6e-10 40.7 0.1 1.3 1 0 0 1 1 1 1 Mitochondrial calcium uniporter DUF1192 PF06698.11 AIN96478.1 - 0.013 15.5 0.1 0.045 13.8 0.1 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF1192) Acetyltransf_10 PF13673.7 AIN96479.1 - 1e-06 28.7 0.0 1.9e-06 27.8 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 AIN96479.1 - 0.0024 18.1 0.0 0.0048 17.1 0.0 1.5 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 AIN96479.1 - 0.0039 17.6 0.0 0.0079 16.6 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain DBD_Tnp_Mut PF03108.15 AIN96479.1 - 0.093 12.7 0.4 0.31 11.1 0.0 2.0 2 0 0 2 2 2 0 MuDR family transposase UPF0242 PF06785.11 AIN96480.1 - 0.53 10.4 2.9 0.93 9.6 2.9 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus ABC_tran_CTD PF16326.5 AIN96480.1 - 3.3 8.0 5.5 0.51 10.6 0.9 1.9 2 0 0 2 2 2 0 ABC transporter C-terminal domain DUF4061 PF13270.6 AIN96481.1 - 0.02 15.2 0.0 0.048 14.0 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4061) Cse1 PF08506.10 AIN96482.1 - 0.0072 15.2 0.0 0.018 13.9 0.0 1.6 1 0 0 1 1 1 1 Cse1 Xpo1 PF08389.12 AIN96482.1 - 0.13 12.3 0.1 1.5 8.8 0.0 2.8 2 0 0 2 2 2 0 Exportin 1-like protein HEAT_EZ PF13513.6 AIN96482.1 - 0.5 10.9 6.5 0.16 12.5 0.3 3.5 3 0 0 3 3 3 0 HEAT-like repeat HEAT PF02985.22 AIN96482.1 - 1.5 9.3 7.1 0.26 11.6 0.2 3.7 3 0 0 3 3 3 0 HEAT repeat DHHC PF01529.20 AIN96483.1 - 4.2e-26 91.6 12.1 4.2e-26 91.6 12.1 2.4 2 1 0 2 2 2 1 DHHC palmitoyltransferase GREB1 PF15782.5 AIN96483.1 - 0.17 9.0 0.8 0.22 8.6 0.8 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Myc_N PF01056.18 AIN96483.1 - 1.2 8.9 6.5 1.9 8.3 6.5 1.2 1 0 0 1 1 1 0 Myc amino-terminal region CAML PF14963.6 AIN96483.1 - 1.9 8.6 5.0 3.5 7.7 5.0 1.4 1 0 0 1 1 1 0 Calcium signal-modulating cyclophilin ligand U-box PF04564.15 AIN96484.1 - 5.8e-05 23.2 0.0 0.00013 22.1 0.0 1.5 1 0 0 1 1 1 1 U-box domain Lectin_leg-like PF03388.13 AIN96485.1 - 7.3e-43 146.5 0.0 1e-42 146.0 0.0 1.1 1 0 0 1 1 1 1 Legume-like lectin family Bact_lectin PF18483.1 AIN96485.1 - 6.7e-09 36.0 0.0 1.1e-08 35.3 0.0 1.3 1 0 0 1 1 1 1 Bacterial lectin TMV_coat PF00721.21 AIN96485.1 - 0.014 15.3 0.2 0.024 14.5 0.2 1.4 1 0 0 1 1 1 0 Virus coat protein (TMV like) PBP1_TM PF14812.6 AIN96485.1 - 6.8 7.1 15.4 23 5.4 15.4 1.9 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Peptidase_M24 PF00557.24 AIN96486.1 - 2.3e-14 53.6 2.1 4e-14 52.8 0.2 2.4 2 1 0 2 2 2 1 Metallopeptidase family M24 PSP1 PF04468.12 AIN96487.1 - 3.2e-21 75.4 0.0 7.2e-21 74.3 0.0 1.6 1 0 0 1 1 1 1 PSP1 C-terminal conserved region Kinesin PF00225.23 AIN96488.1 - 6.5e-33 114.0 0.0 1.2e-09 37.5 0.0 4.9 4 1 0 4 4 4 4 Kinesin motor domain Microtub_bd PF16796.5 AIN96488.1 - 4e-05 23.6 0.0 0.00081 19.4 0.0 2.5 2 1 0 2 2 2 1 Microtubule binding ArfGap PF01412.18 AIN96489.1 - 2e-29 102.1 0.1 3.3e-29 101.3 0.1 1.3 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf ADH_zinc_N PF00107.26 AIN96490.1 - 1.8e-12 47.3 0.0 3.5e-12 46.4 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 AIN96490.1 - 5.6e-11 42.3 0.1 2.9e-10 40.0 0.0 2.0 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 AIN96490.1 - 9.4e-08 33.2 0.0 1.9e-07 32.2 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ubiquitin PF00240.23 AIN96491.1 - 8e-10 38.3 0.0 1.6e-09 37.4 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 AIN96491.1 - 0.0002 21.1 0.0 0.00047 19.9 0.0 1.7 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 AIN96491.1 - 0.0023 18.4 0.1 0.012 16.2 0.0 2.2 2 0 0 2 2 2 1 DUF2407 ubiquitin-like domain Rad60-SLD_2 PF13881.6 AIN96491.1 - 0.0055 16.8 0.0 0.022 14.8 0.0 2.0 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 AIN96491.1 - 0.094 13.2 0.0 0.25 11.8 0.0 1.6 1 0 0 1 1 1 0 Ubiquitin-like domain Anoctamin PF04547.12 AIN96492.1 - 6.5e-68 229.6 0.0 8.7e-68 229.2 0.0 1.1 1 0 0 1 1 1 1 Calcium-activated chloride channel C2 PF00168.30 AIN96494.1 - 1.4e-20 73.5 0.0 3e-20 72.4 0.0 1.6 1 0 0 1 1 1 1 C2 domain DSPc PF00782.20 AIN96495.1 - 2e-08 34.1 0.0 3.8e-08 33.2 0.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Pkinase PF00069.25 AIN96496.1 - 1.6e-40 139.2 0.0 1e-32 113.6 0.0 3.1 2 1 1 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.17 AIN96496.1 - 1.9e-16 60.1 0.0 3.8e-15 55.9 0.0 2.7 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 AIN96496.1 - 3.4e-05 23.3 0.0 9.8e-05 21.8 0.0 1.7 2 0 0 2 2 2 1 Kinase-like CTU2 PF10288.9 AIN96497.1 - 0.00027 21.1 3.2 0.00083 19.6 0.2 3.0 2 1 0 2 2 2 1 Cytoplasmic tRNA 2-thiolation protein 2 SR-25 PF10500.9 AIN96498.1 - 5 6.7 14.5 9.4 5.8 14.5 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Codanin-1_C PF15296.6 AIN96499.1 - 8 6.6 7.9 52 3.9 7.9 2.4 1 0 0 1 1 1 0 Codanin-1 C-terminus Complex1_LYR_2 PF13233.6 AIN96500.1 - 2.5e-06 28.1 0.0 4.8e-06 27.2 0.0 1.4 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.15 AIN96500.1 - 0.011 15.8 0.1 6.5 6.9 0.0 2.7 2 0 0 2 2 2 0 Complex 1 protein (LYR family) Pro-rich PF15240.6 AIN96504.1 - 1.8 8.8 9.5 4.1 7.7 9.6 1.6 1 1 0 1 1 1 0 Proline-rich Peptidase_M16 PF00675.20 AIN96505.1 - 5.7e-06 26.4 0.0 3.4e-05 23.8 0.0 2.2 1 1 0 1 1 1 1 Insulinase (Peptidase family M16) Kinocilin PF15033.6 AIN96505.1 - 0.058 13.0 0.0 0.13 11.9 0.0 1.6 1 0 0 1 1 1 0 Kinocilin protein Flagellin_IN PF07196.13 AIN96505.1 - 0.12 12.6 0.1 0.3 11.3 0.1 1.6 1 0 0 1 1 1 0 Flagellin hook IN motif DUF3381 PF11861.8 AIN96506.1 - 0.62 9.9 0.0 0.62 9.9 0.0 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF3381) Swi3 PF07962.12 AIN96507.1 - 0.076 13.0 0.0 0.18 11.8 0.0 1.7 2 0 0 2 2 2 0 Replication Fork Protection Component Swi3 LRR_6 PF13516.6 AIN96509.1 - 2.1e-07 30.4 3.8 0.082 13.0 0.0 3.8 3 0 0 3 3 3 2 Leucine Rich repeat LRR_8 PF13855.6 AIN96509.1 - 0.00044 20.0 3.0 0.00044 20.0 3.0 2.2 2 1 0 2 2 2 1 Leucine rich repeat LRR_4 PF12799.7 AIN96509.1 - 0.00097 19.5 2.6 0.00097 19.5 2.6 2.8 2 1 1 3 3 3 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 AIN96509.1 - 0.006 17.0 3.9 0.52 11.1 0.5 3.5 2 0 0 2 2 2 1 Leucine Rich Repeat Ax_dynein_light PF10211.9 AIN96510.1 - 0.00018 21.5 4.6 0.00018 21.5 4.6 2.1 2 0 0 2 2 2 1 Axonemal dynein light chain DUF4201 PF13870.6 AIN96510.1 - 0.042 13.6 5.5 0.1 12.3 5.5 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4201) Atg14 PF10186.9 AIN96510.1 - 0.22 10.6 14.2 0.017 14.2 5.4 2.4 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 GvpG PF05120.12 AIN96510.1 - 0.38 10.8 1.9 1.3 9.1 1.9 1.9 1 0 0 1 1 1 0 Gas vesicle protein G Cluap1 PF10234.9 AIN96510.1 - 2.1 7.6 11.9 0.024 14.1 3.7 1.9 2 0 0 2 2 2 0 Clusterin-associated protein-1 PXA PF02194.15 AIN96510.1 - 2.7 8.0 4.6 7.7 6.4 4.6 1.8 1 0 0 1 1 1 0 PXA domain TMF_TATA_bd PF12325.8 AIN96510.1 - 4.2 7.6 14.6 0.59 10.4 6.2 3.0 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding Spc7 PF08317.11 AIN96510.1 - 5.1 5.9 13.0 0.11 11.4 5.0 2.0 2 0 0 2 2 2 0 Spc7 kinetochore protein Glyco_transf_25 PF01755.17 AIN96511.1 - 1.9e-18 67.1 0.0 2.7e-17 63.3 0.0 2.1 1 1 0 1 1 1 1 Glycosyltransferase family 25 (LPS biosynthesis protein) TRM PF02005.16 AIN96512.1 - 1.7e-93 313.8 0.0 2.2e-44 152.2 0.0 3.1 3 0 0 3 3 3 3 N2,N2-dimethylguanosine tRNA methyltransferase Actin PF00022.19 AIN96513.1 - 2.2e-111 372.4 0.0 2.2e-110 369.1 0.0 2.3 1 1 0 1 1 1 1 Actin MreB_Mbl PF06723.13 AIN96513.1 - 0.21 10.4 0.0 11 4.7 0.0 2.1 2 0 0 2 2 2 0 MreB/Mbl protein AAA PF00004.29 AIN96514.1 - 2.7e-37 128.2 0.0 4.6e-37 127.4 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 AIN96514.1 - 2.1e-08 33.8 0.4 4.7e-08 32.7 0.4 1.6 1 0 0 1 1 1 1 AAA+ lid domain Vps4_C PF09336.10 AIN96514.1 - 9e-06 25.6 0.0 2.4e-05 24.2 0.0 1.7 2 0 0 2 2 1 1 Vps4 C terminal oligomerisation domain AAA_22 PF13401.6 AIN96514.1 - 9.3e-06 26.0 2.4 0.027 14.7 0.1 3.3 2 1 1 3 3 3 2 AAA domain RuvB_N PF05496.12 AIN96514.1 - 1.6e-05 24.7 0.0 2.8e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain LisH_TPL PF17814.1 AIN96514.1 - 0.00028 20.5 0.6 0.00062 19.4 0.6 1.6 1 0 0 1 1 1 1 LisH-like dimerisation domain AAA_24 PF13479.6 AIN96514.1 - 0.00031 20.5 0.0 0.0006 19.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 AIN96514.1 - 0.0005 20.5 0.0 0.0015 18.9 0.0 1.9 1 0 0 1 1 1 1 AAA ATPase domain TIP49 PF06068.13 AIN96514.1 - 0.00082 18.7 0.0 0.0014 17.9 0.0 1.2 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_25 PF13481.6 AIN96514.1 - 0.0022 17.6 0.1 0.14 11.7 0.1 2.4 1 1 1 2 2 2 1 AAA domain IstB_IS21 PF01695.17 AIN96514.1 - 0.0046 16.7 0.0 0.01 15.6 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_18 PF13238.6 AIN96514.1 - 0.0086 16.6 0.0 0.025 15.1 0.0 1.8 2 1 0 2 2 1 1 AAA domain AAA_5 PF07728.14 AIN96514.1 - 0.012 15.6 0.1 0.03 14.3 0.1 1.8 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 AIN96514.1 - 0.012 15.7 0.0 0.022 14.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) Mg_chelatase PF01078.21 AIN96514.1 - 0.015 14.7 0.0 0.025 13.9 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_14 PF13173.6 AIN96514.1 - 0.017 15.2 0.0 0.031 14.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 AIN96514.1 - 0.017 14.6 0.0 0.044 13.3 0.0 1.6 1 0 0 1 1 1 0 P-loop containing dynein motor region ATPase PF06745.13 AIN96514.1 - 0.03 13.7 0.1 0.69 9.2 0.1 2.2 1 1 1 2 2 2 0 KaiC RNA_helicase PF00910.22 AIN96514.1 - 0.031 14.7 0.0 0.063 13.7 0.0 1.5 1 0 0 1 1 1 0 RNA helicase PhoH PF02562.16 AIN96514.1 - 0.052 13.0 0.1 0.17 11.3 0.0 1.7 2 0 0 2 2 2 0 PhoH-like protein AAA_33 PF13671.6 AIN96514.1 - 0.054 13.7 0.0 0.1 12.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain Mesothelin PF06060.12 AIN96514.1 - 0.055 11.6 0.0 0.09 11.0 0.0 1.2 1 0 0 1 1 1 0 Pre-pro-megakaryocyte potentiating factor precursor (Mesothelin) AAA_28 PF13521.6 AIN96514.1 - 0.06 13.6 0.1 0.34 11.1 0.0 2.3 3 0 0 3 3 3 0 AAA domain LisH PF08513.11 AIN96514.1 - 0.062 13.3 0.0 0.12 12.4 0.0 1.5 1 0 0 1 1 1 0 LisH A_deaminase PF00962.22 AIN96516.1 - 6e-88 295.3 0.0 1.2e-82 277.9 0.0 2.6 2 1 0 2 2 2 2 Adenosine/AMP deaminase NKAIN PF05640.14 AIN96519.1 - 0.019 14.2 0.8 0.053 12.8 0.1 1.9 2 0 0 2 2 2 0 Na,K-Atpase Interacting protein Wzy_C_2 PF11846.8 AIN96519.1 - 8.4 6.3 12.4 1.8 8.4 1.1 3.2 2 2 1 4 4 4 0 Virulence factor membrane-bound polymerase, C-terminal CAP59_mtransfer PF11735.8 AIN96520.1 - 9e-55 186.0 0.0 3.2e-53 180.9 0.0 2.5 2 1 0 2 2 2 2 Cryptococcal mannosyltransferase 1 Peptidase_S8 PF00082.22 AIN96522.1 - 3.7e-24 85.5 5.7 5.6e-23 81.6 0.0 3.4 4 1 0 4 4 4 2 Subtilase family Dpy-30 PF05186.13 AIN96523.1 - 2.2e-07 30.4 0.4 5e-07 29.3 0.4 1.6 1 0 0 1 1 1 1 Dpy-30 motif FAD_binding_6 PF00970.24 AIN96524.1 - 1.6e-30 105.4 0.0 2.4e-30 104.8 0.0 1.2 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.21 AIN96524.1 - 1.6e-27 96.3 0.0 1.6e-26 93.1 0.0 2.4 2 1 1 3 3 3 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.12 AIN96524.1 - 0.0017 18.5 0.0 0.042 14.0 0.0 2.4 3 0 0 3 3 3 1 Ferric reductase NAD binding domain AAA PF00004.29 AIN96525.1 - 1.7e-42 145.0 0.0 2.8e-42 144.3 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 AIN96525.1 - 6.4e-09 35.5 0.5 1.3e-08 34.5 0.5 1.5 1 0 0 1 1 1 1 AAA+ lid domain Prot_ATP_ID_OB PF16450.5 AIN96525.1 - 5.1e-07 29.6 0.1 1e-06 28.6 0.1 1.6 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_2 PF07724.14 AIN96525.1 - 3.3e-06 27.3 0.0 6.4e-06 26.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 AIN96525.1 - 5.6e-06 26.4 0.1 2e-05 24.6 0.1 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) Prot_ATP_OB_N PF17758.1 AIN96525.1 - 2.3e-05 23.9 0.1 7.5e-05 22.3 0.0 1.9 2 0 0 2 2 1 1 Proteasomal ATPase OB N-terminal domain AAA_16 PF13191.6 AIN96525.1 - 3.3e-05 24.3 0.2 0.0032 17.9 0.0 2.4 1 1 1 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 AIN96525.1 - 4.6e-05 23.7 0.4 0.023 15.0 0.4 2.4 1 1 0 1 1 1 1 AAA domain DUF815 PF05673.13 AIN96525.1 - 0.00048 19.4 0.0 0.00076 18.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) RuvB_N PF05496.12 AIN96525.1 - 0.0014 18.3 0.0 0.0028 17.4 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_18 PF13238.6 AIN96525.1 - 0.0031 18.0 0.0 0.0062 17.1 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 AIN96525.1 - 0.006 16.7 0.0 0.013 15.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_3 PF07726.11 AIN96525.1 - 0.012 15.5 0.0 0.029 14.2 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ATPase PF06745.13 AIN96525.1 - 0.025 13.9 0.2 0.31 10.4 0.1 2.2 1 1 1 2 2 2 0 KaiC RNA_helicase PF00910.22 AIN96525.1 - 0.026 14.9 0.0 0.071 13.5 0.0 1.8 2 0 0 2 2 1 0 RNA helicase AAA_28 PF13521.6 AIN96525.1 - 0.033 14.4 0.1 0.084 13.1 0.0 1.8 2 0 0 2 2 1 0 AAA domain AAA_14 PF13173.6 AIN96525.1 - 0.037 14.1 0.0 0.07 13.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 AIN96525.1 - 0.05 13.3 0.0 0.11 12.2 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_17 PF13207.6 AIN96525.1 - 0.054 13.9 0.0 0.11 13.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 AIN96525.1 - 0.06 13.1 0.5 0.25 11.0 0.2 2.3 2 1 0 2 2 2 0 AAA domain DUF2075 PF09848.9 AIN96525.1 - 0.079 12.2 0.1 0.15 11.2 0.0 1.6 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) NACHT PF05729.12 AIN96525.1 - 0.098 12.6 0.2 0.99 9.3 0.1 2.2 1 1 1 2 2 2 0 NACHT domain TIP49 PF06068.13 AIN96525.1 - 0.1 11.8 0.0 0.19 10.9 0.0 1.3 1 0 0 1 1 1 0 TIP49 P-loop domain Mg_chelatase PF01078.21 AIN96525.1 - 0.11 11.9 0.0 0.21 11.0 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI NB-ARC PF00931.22 AIN96525.1 - 0.16 11.2 0.0 0.97 8.6 0.0 2.3 4 0 0 4 4 4 0 NB-ARC domain AAA_25 PF13481.6 AIN96525.1 - 0.22 11.1 0.8 5.4 6.6 0.3 2.5 1 1 1 2 2 2 0 AAA domain tRNA-synt_1 PF00133.22 AIN96526.1 - 2e-28 99.0 0.0 1e-09 37.2 0.0 4.0 3 1 0 3 3 3 3 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.11 AIN96526.1 - 3.3e-20 72.2 0.0 5.3e-10 38.6 0.0 3.0 3 0 0 3 3 3 2 tRNA synthetases class I (M) Anticodon_1 PF08264.13 AIN96526.1 - 4.4e-12 46.2 0.3 1.1e-11 45.0 0.3 1.7 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.19 AIN96526.1 - 2.1e-07 30.6 0.0 4.7e-07 29.5 0.0 1.5 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain YxiJ PF14176.6 AIN96526.1 - 0.0096 16.4 0.3 0.85 10.1 0.3 2.6 2 0 0 2 2 2 1 YxiJ-like protein Methyltransf_23 PF13489.6 AIN96527.1 - 0.044 13.6 0.2 0.044 13.6 0.2 2.5 2 1 1 3 3 3 0 Methyltransferase domain Clathrin_H_link PF13838.6 AIN96527.1 - 0.97 9.4 7.6 2.2 8.3 0.6 2.8 2 0 0 2 2 2 0 Clathrin-H-link RNA_pol_N PF01194.17 AIN96528.1 - 1.3e-25 89.4 1.5 1.8e-25 89.0 1.5 1.2 1 0 0 1 1 1 1 RNA polymerases N / 8 kDa subunit DUF155 PF02582.14 AIN96529.1 - 1e-38 133.2 0.0 1.5e-38 132.6 0.0 1.3 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 DUF780 PF05611.11 AIN96529.1 - 0.76 10.6 17.9 0.17 12.6 9.6 2.5 2 0 0 2 2 2 0 Caenorhabditis elegans protein of unknown function (DUF780) Abhydrolase_6 PF12697.7 AIN96530.1 - 1.2e-13 52.1 2.6 2.5e-12 47.9 2.6 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 AIN96530.1 - 7.2e-10 38.9 0.9 4.8e-05 23.1 0.7 2.6 2 1 0 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 AIN96530.1 - 0.00027 20.3 0.0 0.0011 18.2 0.1 1.9 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Esterase PF00756.20 AIN96530.1 - 0.011 15.3 0.0 0.02 14.5 0.0 1.4 1 0 0 1 1 1 0 Putative esterase LCAT PF02450.15 AIN96530.1 - 0.012 14.9 0.0 0.017 14.3 0.0 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase Abhydro_lipase PF04083.16 AIN96530.1 - 0.093 12.3 0.1 0.27 10.8 0.0 1.8 2 0 0 2 2 2 0 Partial alpha/beta-hydrolase lipase region DUF2939 PF11159.8 AIN96530.1 - 0.13 12.7 0.0 0.37 11.2 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2939) LIDHydrolase PF10230.9 AIN96530.1 - 0.13 11.8 0.0 1.3 8.5 0.0 2.0 2 0 0 2 2 2 0 Lipid-droplet associated hydrolase PGAP1 PF07819.13 AIN96530.1 - 0.13 11.9 0.1 0.44 10.2 0.0 1.9 2 0 0 2 2 2 0 PGAP1-like protein Endonuc-BglII PF09195.11 AIN96531.1 - 0.067 13.0 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 Restriction endonuclease BglII EF-hand_1 PF00036.32 AIN96532.1 - 1.4e-14 52.5 1.9 1.1e-07 30.9 0.0 3.8 5 0 0 5 5 5 2 EF hand EF-hand_7 PF13499.6 AIN96532.1 - 1.7e-14 54.0 0.1 1.1e-06 29.0 0.1 2.6 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_8 PF13833.6 AIN96532.1 - 3.7e-10 39.5 0.8 0.0013 18.6 0.0 3.7 3 1 1 4 4 4 3 EF-hand domain pair EF-hand_6 PF13405.6 AIN96532.1 - 9.6e-10 37.6 0.1 1.3e-05 24.7 0.0 3.7 2 1 1 3 3 3 2 EF-hand domain EF-hand_5 PF13202.6 AIN96532.1 - 3.1e-05 23.3 0.1 3.1e-05 23.3 0.1 2.8 3 1 1 4 4 4 1 EF hand EF-hand_9 PF14658.6 AIN96532.1 - 0.0054 17.0 0.0 1.2 9.5 0.0 2.5 2 0 0 2 2 2 1 EF-hand domain DUF4192 PF13830.6 AIN96532.1 - 0.02 15.0 1.2 0.024 14.7 1.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4192) MAM33 PF02330.16 AIN96533.1 - 2.4e-09 37.4 0.0 6.5e-09 36.0 0.0 1.7 2 0 0 2 2 2 1 Mitochondrial glycoprotein Tctex-1 PF03645.13 AIN96534.1 - 1.5e-23 83.0 0.0 2.4e-23 82.3 0.0 1.3 1 1 0 1 1 1 1 Tctex-1 family Rio2_N PF09202.11 AIN96534.1 - 0.12 12.6 0.0 0.26 11.5 0.0 1.6 2 0 0 2 2 2 0 Rio2, N-terminal Adenylsucc_synt PF00709.21 AIN96535.1 - 1.1e-91 307.8 0.0 1.4e-91 307.5 0.0 1.1 1 0 0 1 1 1 1 Adenylosuccinate synthetase Ribosomal_L27 PF01016.19 AIN96536.1 - 0.12 12.4 0.4 0.23 11.5 0.4 1.6 1 1 0 1 1 1 0 Ribosomal L27 protein RsgA_N PF16745.5 AIN96536.1 - 0.13 12.0 0.0 0.23 11.3 0.0 1.4 1 0 0 1 1 1 0 RsgA N-terminal domain Nucleoside_tran PF01733.18 AIN96537.1 - 1.9e-28 99.8 8.5 3.2e-26 92.4 8.5 2.4 1 1 0 1 1 1 1 Nucleoside transporter Ribosomal_S4e PF00900.20 AIN96538.1 - 6e-25 86.9 0.0 9.6e-25 86.3 0.0 1.3 1 0 0 1 1 1 1 Ribosomal family S4e RS4NT PF08071.12 AIN96538.1 - 8.7e-18 64.2 4.7 1.9e-17 63.0 4.7 1.6 1 0 0 1 1 1 1 RS4NT (NUC023) domain 40S_S4_C PF16121.5 AIN96538.1 - 1.4e-16 59.9 0.0 2.5e-16 59.0 0.0 1.4 1 0 0 1 1 1 1 40S ribosomal protein S4 C-terminus S4 PF01479.25 AIN96538.1 - 3.3e-07 29.9 0.1 1.1e-06 28.2 0.0 2.0 2 0 0 2 2 2 1 S4 domain KOW PF00467.29 AIN96538.1 - 2.3e-06 27.3 0.7 2.3e-06 27.3 0.7 1.9 2 0 0 2 2 2 1 KOW motif TPK_catalytic PF04263.16 AIN96539.1 - 1.1e-11 44.8 0.0 1.4e-05 25.2 0.0 3.1 2 1 0 2 2 2 2 Thiamin pyrophosphokinase, catalytic domain TPK_B1_binding PF04265.14 AIN96539.1 - 8e-07 28.7 0.0 2e-06 27.4 0.0 1.6 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, vitamin B1 binding domain TetR_C_6 PF13977.6 AIN96539.1 - 0.048 13.9 0.6 0.1 12.8 0.6 1.5 1 0 0 1 1 1 0 BetI-type transcriptional repressor, C-terminal PARP PF00644.20 AIN96539.1 - 0.091 12.3 0.0 0.15 11.6 0.0 1.3 1 0 0 1 1 1 0 Poly(ADP-ribose) polymerase catalytic domain Herpes_LMP1 PF05297.11 AIN96540.1 - 0.047 12.9 0.0 0.054 12.7 0.0 1.1 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) gpUL132 PF11359.8 AIN96540.1 - 0.051 13.1 0.0 0.063 12.8 0.0 1.2 1 0 0 1 1 1 0 Glycoprotein UL132 DUF2561 PF10812.8 AIN96541.1 - 0.025 14.6 0.0 0.031 14.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2561) TMEM154 PF15102.6 AIN96541.1 - 0.053 13.4 0.0 0.17 11.8 0.0 1.7 2 0 0 2 2 2 0 TMEM154 protein family TMEM132D_C PF15706.5 AIN96541.1 - 0.12 12.2 0.1 0.26 11.1 0.1 1.5 1 0 0 1 1 1 0 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term Prominin PF05478.11 AIN96541.1 - 0.15 10.0 0.1 0.17 9.8 0.1 1.1 1 0 0 1 1 1 0 Prominin PRIMA1 PF16101.5 AIN96541.1 - 0.19 11.8 0.0 0.29 11.2 0.0 1.3 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 Insulin_TMD PF17870.1 AIN96541.1 - 0.34 11.0 2.9 0.59 10.3 2.9 1.3 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment Endonuclease_NS PF01223.23 AIN96542.1 - 4e-18 66.1 0.0 1.3e-17 64.4 0.0 1.7 2 0 0 2 2 2 1 DNA/RNA non-specific endonuclease ATP_bind_1 PF03029.17 AIN96543.1 - 6.2e-60 203.0 0.1 5.9e-59 199.8 0.1 1.9 1 1 0 1 1 1 1 Conserved hypothetical ATP binding protein GTP_EFTU PF00009.27 AIN96543.1 - 5.3e-05 22.8 0.0 0.073 12.6 0.0 2.7 2 1 0 2 2 2 2 Elongation factor Tu GTP binding domain SRP54 PF00448.22 AIN96543.1 - 5.5e-05 22.9 0.0 0.0015 18.2 0.0 2.3 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain AAA_16 PF13191.6 AIN96543.1 - 6.1e-05 23.5 0.0 0.00015 22.2 0.0 2.0 2 1 0 2 2 2 1 AAA ATPase domain MMR_HSR1 PF01926.23 AIN96543.1 - 7.3e-05 22.8 0.0 0.00014 21.9 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 AIN96543.1 - 0.00046 20.1 0.1 2.2 8.1 0.1 3.5 3 1 0 3 3 3 2 RsgA GTPase AAA_24 PF13479.6 AIN96543.1 - 0.00053 19.8 0.0 0.001 18.8 0.0 1.5 1 1 0 1 1 1 1 AAA domain cobW PF02492.19 AIN96543.1 - 0.0026 17.4 0.6 0.27 10.8 0.0 2.5 2 1 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain Arf PF00025.21 AIN96543.1 - 0.003 17.0 0.0 0.24 10.8 0.0 2.3 2 0 0 2 2 2 1 ADP-ribosylation factor family AAA_33 PF13671.6 AIN96543.1 - 0.0033 17.6 0.0 0.0053 16.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 AIN96543.1 - 0.0044 17.3 0.0 0.017 15.4 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 AIN96543.1 - 0.0099 15.6 0.0 0.027 14.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_7 PF12775.7 AIN96543.1 - 0.01 15.3 0.0 0.017 14.7 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region NB-ARC PF00931.22 AIN96543.1 - 0.012 14.8 0.0 0.022 13.9 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain NACHT PF05729.12 AIN96543.1 - 0.018 15.0 0.0 0.045 13.7 0.0 1.7 1 0 0 1 1 1 0 NACHT domain MeaB PF03308.16 AIN96543.1 - 0.019 14.0 0.1 0.86 8.5 0.0 2.9 2 2 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB SRPRB PF09439.10 AIN96543.1 - 0.022 14.2 0.0 0.75 9.2 0.0 2.2 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit Roc PF08477.13 AIN96543.1 - 0.024 14.8 0.0 0.34 11.1 0.0 2.3 2 1 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_19 PF13245.6 AIN96543.1 - 0.025 14.9 0.2 0.046 14.1 0.2 1.5 1 1 0 1 1 1 0 AAA domain AAA_18 PF13238.6 AIN96543.1 - 0.039 14.5 0.0 0.073 13.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain DLIC PF05783.11 AIN96543.1 - 0.045 12.6 0.2 0.28 10.0 0.0 1.9 2 0 0 2 2 2 0 Dynein light intermediate chain (DLIC) Ras PF00071.22 AIN96543.1 - 0.05 13.2 0.3 2.3 7.8 0.0 2.6 3 1 0 3 3 3 0 Ras family Zeta_toxin PF06414.12 AIN96543.1 - 0.06 12.6 0.4 0.14 11.5 0.0 1.8 2 0 0 2 2 2 0 Zeta toxin AAA PF00004.29 AIN96543.1 - 0.073 13.5 0.0 0.16 12.4 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PduV-EutP PF10662.9 AIN96543.1 - 0.092 12.5 0.0 0.57 9.9 0.0 2.2 2 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Septin PF00735.18 AIN96543.1 - 0.099 11.9 0.1 0.51 9.6 0.1 2.2 1 1 0 1 1 1 0 Septin NTPase_1 PF03266.15 AIN96543.1 - 0.1 12.5 0.2 0.32 10.9 0.2 2.0 1 1 0 1 1 1 0 NTPase AAA_5 PF07728.14 AIN96543.1 - 0.11 12.5 0.0 0.18 11.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) MobB PF03205.14 AIN96543.1 - 0.15 12.0 0.0 0.34 10.8 0.0 1.6 2 0 0 2 2 1 0 Molybdopterin guanine dinucleotide synthesis protein B G-alpha PF00503.20 AIN96543.1 - 0.16 11.1 0.0 4.1 6.5 0.0 2.1 2 0 0 2 2 2 0 G-protein alpha subunit APS_kinase PF01583.20 AIN96543.1 - 0.16 11.8 0.0 0.41 10.5 0.0 1.7 2 0 0 2 2 1 0 Adenylylsulphate kinase DRIM PF07539.12 AIN96544.1 - 0.074 11.3 0.0 0.11 10.8 0.0 1.1 1 0 0 1 1 1 0 Down-regulated in metastasis Complex1_LYR_1 PF13232.6 AIN96545.1 - 3.4e-41 139.8 1.7 5.1e-41 139.2 1.7 1.3 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.15 AIN96545.1 - 2.8e-05 24.1 1.0 4.2e-05 23.5 0.2 1.8 2 0 0 2 2 2 1 Complex 1 protein (LYR family) DUF4771 PF15995.5 AIN96545.1 - 0.0065 16.7 0.8 0.011 16.0 0.8 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4771) DUF5075 PF16825.5 AIN96546.1 - 1.2e-07 31.7 0.4 3.5e-07 30.1 0.3 1.9 1 1 0 1 1 1 1 IGP family C-type lectin domain DUF3742 PF12553.8 AIN96546.1 - 0.041 14.0 0.1 0.085 13.0 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3742) zf-LITAF-like PF10601.9 AIN96546.1 - 0.26 11.6 1.2 0.68 10.2 1.2 1.7 1 0 0 1 1 1 0 LITAF-like zinc ribbon domain DUF5075 PF16825.5 AIN96547.1 - 2.6e-11 43.6 3.7 4.8e-11 42.7 3.7 1.5 1 1 0 1 1 1 1 IGP family C-type lectin domain Ferlin_C PF16165.5 AIN96547.1 - 0.017 15.1 0.3 0.032 14.2 0.3 1.4 1 0 0 1 1 1 0 Ferlin C-terminus DUF4492 PF14899.6 AIN96547.1 - 0.076 13.0 2.7 0.15 12.0 2.7 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4492) PRIMA1 PF16101.5 AIN96547.1 - 3.1 7.8 6.1 0.53 10.3 1.8 1.9 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 TMIE PF16038.5 AIN96547.1 - 6.5 6.7 5.1 11 5.9 5.1 1.3 1 0 0 1 1 1 0 TMIE protein TPR_16 PF13432.6 AIN96549.1 - 0.027 15.1 1.5 0.027 15.1 1.5 3.2 4 0 0 4 4 4 0 Tetratricopeptide repeat Dpy-30 PF05186.13 AIN96550.1 - 1.8e-13 49.9 0.6 3.6e-13 49.0 0.6 1.5 1 0 0 1 1 1 1 Dpy-30 motif Hydin_ADK PF17213.3 AIN96550.1 - 5.3e-05 23.6 0.0 5.3e-05 23.6 0.0 2.4 3 0 0 3 3 3 1 Hydin Adenylate kinase-like domain AAA_17 PF13207.6 AIN96550.1 - 0.022 15.2 0.0 2.7 8.4 0.0 3.3 2 1 1 3 3 3 0 AAA domain AAA PF00004.29 AIN96550.1 - 0.082 13.3 0.0 0.17 12.3 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Fib_alpha PF08702.10 AIN96551.1 - 1 9.6 3.8 2.1 8.5 0.4 2.6 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family Sin_N PF04801.13 AIN96552.1 - 9.3e-77 259.0 0.3 1.9e-76 258.0 0.2 1.5 2 0 0 2 2 2 1 Sin-like protein conserved region Laminin_I PF06008.14 AIN96552.1 - 0.062 13.0 0.1 0.18 11.5 0.1 1.7 1 0 0 1 1 1 0 Laminin Domain I EMP70 PF02990.16 AIN96553.1 - 4.4e-107 358.9 15.6 6.6e-107 358.3 15.6 1.2 1 0 0 1 1 1 1 Endomembrane protein 70 WD40 PF00400.32 AIN96554.1 - 1.9 9.5 8.0 68 4.6 0.1 5.3 6 0 0 6 6 6 0 WD domain, G-beta repeat LRR_4 PF12799.7 AIN96557.1 - 1.5e-07 31.6 13.6 6.3e-07 29.6 2.5 3.5 1 1 2 3 3 3 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 AIN96557.1 - 0.00013 21.6 6.3 0.00013 21.6 6.3 2.5 2 0 0 2 2 2 1 Leucine rich repeat LRR_9 PF14580.6 AIN96557.1 - 0.09 12.3 0.1 0.17 11.4 0.1 1.3 1 0 0 1 1 1 0 Leucine-rich repeat LRR_1 PF00560.33 AIN96557.1 - 0.85 10.4 6.7 15 6.7 0.0 4.2 5 0 0 5 5 5 0 Leucine Rich Repeat LRR_6 PF13516.6 AIN96557.1 - 5.3 7.4 9.5 13 6.2 0.3 3.7 3 1 1 4 4 4 0 Leucine Rich repeat EF-hand_1 PF00036.32 AIN96559.1 - 2e-22 77.0 0.0 4.2e-06 25.9 0.0 5.2 5 0 0 5 5 5 5 EF hand EF-hand_7 PF13499.6 AIN96559.1 - 6.1e-21 74.7 0.0 1.2e-09 38.4 0.0 3.1 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_6 PF13405.6 AIN96559.1 - 1.5e-19 68.2 1.0 0.00027 20.6 0.1 5.1 5 0 0 5 5 5 4 EF-hand domain EF-hand_5 PF13202.6 AIN96559.1 - 1.6e-15 55.8 1.0 7.2e-06 25.3 0.0 3.8 4 0 0 4 4 4 3 EF hand EF-hand_8 PF13833.6 AIN96559.1 - 3.9e-14 52.2 0.1 0.0003 20.6 0.0 4.5 3 2 2 5 5 5 3 EF-hand domain pair EF-hand_9 PF14658.6 AIN96559.1 - 0.0012 19.1 0.0 0.57 10.6 0.0 3.1 3 0 0 3 3 3 1 EF-hand domain EF-hand_10 PF14788.6 AIN96559.1 - 0.023 14.6 0.0 0.5 10.3 0.0 2.8 3 0 0 3 3 3 0 EF hand PAH PF02671.21 AIN96559.1 - 0.099 12.8 0.0 0.52 10.5 0.0 2.3 2 1 0 2 2 2 0 Paired amphipathic helix repeat HECT PF00632.25 AIN96560.1 - 8.2e-43 147.0 0.0 1.6e-42 146.0 0.0 1.4 1 1 0 1 1 1 1 HECT-domain (ubiquitin-transferase) SPRY PF00622.28 AIN96560.1 - 2.4e-26 92.2 0.4 5.2e-10 39.5 0.0 3.9 3 0 0 3 3 3 3 SPRY domain Ran_BP1 PF00638.18 AIN96561.1 - 4.6e-26 91.5 1.5 6e-26 91.1 1.5 1.1 1 0 0 1 1 1 1 RanBP1 domain Polyketide_cyc2 PF10604.9 AIN96561.1 - 0.01 16.1 0.3 0.012 15.9 0.3 1.2 1 0 0 1 1 1 0 Polyketide cyclase / dehydrase and lipid transport DRMBL PF07522.14 AIN96562.1 - 0.16 12.2 0.0 0.33 11.2 0.0 1.5 1 0 0 1 1 1 0 DNA repair metallo-beta-lactamase PIN_4 PF13638.6 AIN96563.1 - 1.3e-16 61.0 0.0 2.9e-16 59.9 0.0 1.5 1 0 0 1 1 1 1 PIN domain Metallophos PF00149.28 AIN96564.1 - 3.2e-22 80.1 0.0 5.1e-22 79.4 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase AAA PF00004.29 AIN96566.1 - 1.5e-15 57.8 0.0 3.9e-15 56.4 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 AIN96566.1 - 0.19 12.1 0.0 1.2 9.5 0.0 2.3 2 0 0 2 2 2 0 RNA helicase AAA_16 PF13191.6 AIN96566.1 - 0.24 11.8 0.1 0.24 11.8 0.1 3.7 2 2 0 2 2 2 0 AAA ATPase domain PhoLip_ATPase_C PF16212.5 AIN96567.1 - 1.6e-67 227.9 19.5 1.6e-67 227.9 19.5 2.2 3 0 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 AIN96567.1 - 1e-22 79.6 4.1 1e-22 79.6 4.1 3.2 3 0 0 3 3 3 1 Phospholipid-translocating ATPase N-terminal E1-E2_ATPase PF00122.20 AIN96567.1 - 1.3e-09 37.9 0.0 1.3e-09 37.9 0.0 3.4 3 1 0 3 3 3 1 E1-E2 ATPase Cation_ATPase PF13246.6 AIN96567.1 - 4.5e-09 36.3 0.0 4.3e-08 33.1 0.0 2.2 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 AIN96567.1 - 6.6e-09 36.4 0.1 5e-05 23.7 0.1 3.0 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 AIN96567.1 - 0.027 14.2 0.0 0.062 13.0 0.0 1.5 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase PMC2NT PF08066.12 AIN96568.1 - 0.06 14.0 0.0 0.13 12.9 0.0 1.5 1 0 0 1 1 1 0 PMC2NT (NUC016) domain NIF PF03031.18 AIN96568.1 - 0.15 11.8 0.0 1.3 8.8 0.0 2.1 2 0 0 2 2 2 0 NLI interacting factor-like phosphatase Gtr1_RagA PF04670.12 AIN96570.1 - 2.4e-91 305.2 0.0 3e-91 304.9 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Roc PF08477.13 AIN96570.1 - 2.1e-06 27.9 0.0 1.6e-05 25.1 0.0 2.1 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 AIN96570.1 - 3.6e-05 23.4 0.0 0.00014 21.5 0.0 2.0 3 0 0 3 3 3 1 Ras family Arf PF00025.21 AIN96570.1 - 0.00037 20.0 0.0 0.002 17.6 0.0 2.1 2 0 0 2 2 2 1 ADP-ribosylation factor family Metallophos PF00149.28 AIN96571.1 - 4.6e-22 79.5 0.0 8.1e-22 78.7 0.0 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 AIN96571.1 - 0.18 12.2 0.0 1.6 9.2 0.0 2.6 3 0 0 3 3 3 0 Serine-threonine protein phosphatase N-terminal domain UQ_con PF00179.26 AIN96572.1 - 3.8e-15 55.8 0.0 4e-15 55.7 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 AIN96572.1 - 0.0025 18.1 0.0 0.0027 18.0 0.0 1.2 1 0 0 1 1 1 1 RWD domain LD_cluster2 PF18163.1 AIN96572.1 - 0.026 14.0 0.1 0.034 13.7 0.1 1.1 1 0 0 1 1 1 0 SLOG cluster2 Tcp10_C PF07202.13 AIN96573.1 - 6e-25 88.2 1.5 8.3e-25 87.7 0.1 2.0 2 0 0 2 2 2 1 T-complex protein 10 C-terminus PSI_PsaF PF02507.15 AIN96573.1 - 0.04 13.8 0.5 0.11 12.3 0.5 1.7 1 0 0 1 1 1 0 Photosystem I reaction centre subunit III Seadorna_VP6 PF07407.11 AIN96573.1 - 0.22 10.4 0.3 0.34 9.8 0.3 1.2 1 0 0 1 1 1 0 Seadornavirus VP6 protein FAP206 PF12018.8 AIN96573.1 - 1.5 8.2 7.3 3.5 7.0 7.3 1.6 1 0 0 1 1 1 0 Domain of unknown function Tmemb_185A PF10269.9 AIN96574.1 - 0.11 12.2 0.1 0.2 11.3 0.1 1.3 1 0 0 1 1 1 0 Transmembrane Fragile-X-F protein DUF3907 PF13047.6 AIN96574.1 - 0.32 11.0 2.7 5.6 6.9 0.1 3.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3907) DUF2890 PF11081.8 AIN96574.1 - 0.96 9.5 9.4 1 9.5 3.0 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2890) DUF4145 PF13643.6 AIN96574.1 - 1.9 8.6 5.6 29 4.9 0.2 4.9 4 0 0 4 4 4 0 Domain of unknown function (DUF4145) DUF1722 PF08349.11 AIN96574.1 - 5.8 7.2 10.1 0.5 10.7 0.5 3.7 4 0 0 4 4 4 0 Protein of unknown function (DUF1722) Kinesin PF00225.23 AIN96575.1 - 3.7e-92 308.8 0.0 5.3e-92 308.3 0.0 1.2 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 AIN96575.1 - 2e-16 60.3 0.0 4.1e-16 59.2 0.0 1.5 1 0 0 1 1 1 1 Microtubule binding SAM_1 PF00536.30 AIN96575.1 - 0.00021 21.7 0.2 0.00021 21.7 0.2 2.1 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) BLOC1_2 PF10046.9 AIN96575.1 - 0.066 13.5 0.0 0.18 12.2 0.0 1.7 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 SAM_2 PF07647.17 AIN96575.1 - 0.091 12.9 0.2 0.2 11.8 0.2 1.6 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) SE PF08491.10 AIN96576.1 - 6.8e-59 199.2 0.0 9.7e-59 198.7 0.0 1.2 1 0 0 1 1 1 1 Squalene epoxidase FAD_binding_3 PF01494.19 AIN96576.1 - 5.9e-08 32.3 0.0 3.9e-07 29.7 0.0 2.2 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 AIN96576.1 - 0.0045 16.3 0.1 0.0083 15.4 0.1 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GDI PF00996.18 AIN96576.1 - 0.027 13.0 0.0 0.039 12.5 0.0 1.2 1 0 0 1 1 1 0 GDP dissociation inhibitor FAD_oxidored PF12831.7 AIN96576.1 - 0.044 13.1 0.1 0.06 12.7 0.1 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 AIN96576.1 - 0.064 13.5 0.0 0.17 12.2 0.0 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 AIN96576.1 - 0.17 10.9 0.0 3.1 6.7 0.0 2.1 2 0 0 2 2 2 0 Lycopene cyclase protein GIDA PF01134.22 AIN96576.1 - 0.17 11.0 0.1 0.35 9.9 0.0 1.5 2 0 0 2 2 2 0 Glucose inhibited division protein A BEN PF10523.9 AIN96576.1 - 0.17 12.1 0.1 0.57 10.4 0.0 1.9 2 0 0 2 2 2 0 BEN domain DNA_pol_A PF00476.20 AIN96577.1 - 4.7e-37 127.9 0.2 1.3e-36 126.5 0.1 1.8 2 0 0 2 2 2 1 DNA polymerase family A DNA_pol_A_exo1 PF01612.20 AIN96577.1 - 2.7e-05 24.0 0.0 7.2e-05 22.6 0.0 1.7 1 0 0 1 1 1 1 3'-5' exonuclease Pkinase PF00069.25 AIN96578.1 - 9.7e-52 175.9 0.0 5.1e-30 104.7 0.0 3.7 3 1 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 AIN96578.1 - 7e-21 74.7 0.0 7.5e-17 61.5 0.0 2.6 3 0 0 3 3 3 2 Protein tyrosine kinase Haspin_kinase PF12330.8 AIN96578.1 - 0.0012 17.8 0.0 0.0019 17.2 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 AIN96578.1 - 0.015 14.7 0.0 0.026 13.9 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family AAA_6 PF12774.7 AIN96579.1 - 6e-141 469.1 0.0 7.6e-140 465.5 0.0 2.6 2 0 0 2 2 2 1 Hydrolytic ATP binding site of dynein motor region DHC_N1 PF08385.12 AIN96579.1 - 3.4e-133 445.2 0.1 1.3e-131 440.0 0.0 2.8 2 0 0 2 2 2 1 Dynein heavy chain, N-terminal region 1 DHC_N2 PF08393.13 AIN96579.1 - 1.3e-111 373.6 4.9 1.3e-111 373.6 4.9 3.4 3 0 0 3 3 3 1 Dynein heavy chain, N-terminal region 2 AAA_8 PF12780.7 AIN96579.1 - 7.8e-96 320.4 0.4 2.2e-95 318.9 0.0 2.1 2 0 0 2 2 2 1 P-loop containing dynein motor region D4 MT PF12777.7 AIN96579.1 - 1.9e-83 280.4 10.5 4.1e-83 279.3 10.5 1.6 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_9 PF12781.7 AIN96579.1 - 9.1e-83 276.7 0.1 9.1e-83 276.7 0.1 3.1 3 0 0 3 3 3 1 ATP-binding dynein motor region Dynein_C PF18199.1 AIN96579.1 - 2e-75 253.9 0.1 6.9e-75 252.1 0.1 2.0 1 0 0 1 1 1 1 Dynein heavy chain C-terminal domain AAA_7 PF12775.7 AIN96579.1 - 4e-68 228.5 0.5 3.2e-63 212.5 0.1 3.9 4 0 0 4 4 3 2 P-loop containing dynein motor region AAA_lid_11 PF18198.1 AIN96579.1 - 6.4e-46 156.2 0.0 1.8e-45 154.7 0.0 1.9 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain Dynein_heavy PF03028.15 AIN96579.1 - 3.9e-36 123.7 0.1 1e-21 77.2 0.0 4.7 4 0 0 4 4 4 2 Dynein heavy chain region D6 P-loop domain AAA_lid_1 PF17857.1 AIN96579.1 - 3.1e-26 91.5 0.2 1.9e-25 89.0 0.2 2.5 1 0 0 1 1 1 1 AAA+ lid domain Dynein_AAA_lid PF17852.1 AIN96579.1 - 8.3e-24 84.1 0.2 3.3e-23 82.2 0.2 2.2 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain AAA_5 PF07728.14 AIN96579.1 - 1.2e-20 73.9 0.1 1.7e-07 31.3 0.0 5.8 5 0 0 5 5 5 3 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 AIN96579.1 - 4.9e-08 33.6 0.5 0.04 14.5 0.0 6.4 6 0 0 6 6 5 1 AAA domain AAA PF00004.29 AIN96579.1 - 3e-06 27.7 0.0 0.18 12.3 0.0 3.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 AIN96579.1 - 4.6e-05 23.7 0.3 3.8 7.8 0.0 5.0 5 0 0 5 5 3 1 AAA domain AAA_16 PF13191.6 AIN96579.1 - 0.00018 22.0 9.4 0.29 11.5 0.1 6.3 6 1 1 7 7 5 1 AAA ATPase domain AAA_19 PF13245.6 AIN96579.1 - 0.00025 21.4 0.6 0.66 10.3 0.0 3.8 3 0 0 3 3 3 1 AAA domain Mg_chelatase PF01078.21 AIN96579.1 - 0.0068 15.8 0.2 0.71 9.2 0.0 3.7 4 0 0 4 4 4 1 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.22 AIN96579.1 - 0.033 14.6 1.5 69 3.9 0.0 4.8 4 0 0 4 4 4 0 RNA helicase TsaE PF02367.17 AIN96579.1 - 0.04 13.9 0.5 27 4.8 0.1 3.8 3 0 0 3 3 3 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE DUF815 PF05673.13 AIN96579.1 - 0.062 12.5 0.0 0.9 8.6 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF815) GP3_package PF16677.5 AIN96579.1 - 0.58 10.3 2.8 3.6 7.8 2.3 2.7 2 0 0 2 2 2 0 DNA-packaging protein gp3 AAA_28 PF13521.6 AIN96579.1 - 0.82 9.9 4.8 26 5.0 0.1 4.2 4 0 0 4 4 3 0 AAA domain Cpn60_TCP1 PF00118.24 AIN96580.1 - 2.8e-163 544.1 8.1 3.2e-163 543.9 8.1 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family GARS_N PF02844.15 AIN96580.1 - 0.069 13.9 0.0 2.3 9.1 0.0 2.9 2 1 0 2 2 2 0 Phosphoribosylglycinamide synthetase, N domain Ribosomal_L44 PF00935.19 AIN96581.1 - 1.2e-31 109.0 9.1 1.7e-31 108.5 9.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L44 P5CR_dimer PF14748.6 AIN96582.1 - 6.3e-36 122.7 0.8 1.1e-35 122.0 0.8 1.4 1 0 0 1 1 1 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.17 AIN96582.1 - 2e-17 63.6 0.0 4.7e-17 62.4 0.0 1.7 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.15 AIN96582.1 - 4.8e-05 23.6 0.1 9.3e-05 22.6 0.1 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase Shikimate_DH PF01488.20 AIN96582.1 - 0.0008 19.5 0.1 0.0015 18.6 0.1 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase ApbA PF02558.16 AIN96582.1 - 0.0013 18.4 0.6 0.0052 16.4 0.5 1.9 1 1 0 1 1 1 1 Ketopantoate reductase PanE/ApbA IlvN PF07991.12 AIN96582.1 - 0.0095 15.5 0.0 0.015 14.9 0.0 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain MFS_1 PF07690.16 AIN96583.1 - 6.7e-12 45.0 36.0 5.9e-09 35.3 27.4 2.4 2 0 0 2 2 2 2 Major Facilitator Superfamily Nodulin-like PF06813.13 AIN96583.1 - 5.7e-08 32.6 15.8 5.7e-08 32.6 15.8 2.7 2 1 0 2 2 2 1 Nodulin-like HbrB PF08539.11 AIN96583.1 - 0.07 13.1 0.2 0.12 12.3 0.1 1.5 1 1 0 1 1 1 0 HbrB-like SfLAP PF11139.8 AIN96583.1 - 0.073 12.5 8.4 2 7.8 8.4 2.9 1 1 0 1 1 1 0 Sap, sulfolipid-1-addressing protein DUF1129 PF06570.11 AIN96583.1 - 1.9 7.9 10.0 3 7.3 1.4 3.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1129) E1-E2_ATPase PF00122.20 AIN96583.1 - 8 5.9 7.0 10 5.6 0.4 2.8 3 0 0 3 3 3 0 E1-E2 ATPase LRR_4 PF12799.7 AIN96584.1 - 2.1e-12 47.1 0.0 0.034 14.6 0.0 5.7 5 1 0 5 5 5 4 Leucine Rich repeats (2 copies) KH_6 PF15985.5 AIN96585.1 - 3e-12 46.7 0.1 5.3e-11 42.7 0.0 2.5 2 0 0 2 2 2 1 KH domain FAA_hydrolase_N PF09298.11 AIN96586.1 - 0.21 11.8 0.9 14 5.9 0.1 2.5 1 1 0 2 2 2 0 Fumarylacetoacetase N-terminal SNF2_N PF00176.23 AIN96587.1 - 9.4e-22 77.2 0.0 2e-21 76.1 0.0 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain Tet_JBP PF12851.7 AIN96587.1 - 2.2e-21 76.5 0.2 4e-17 62.6 0.0 2.3 1 1 1 2 2 2 2 Oxygenase domain of the 2OGFeDO superfamily Helicase_C PF00271.31 AIN96587.1 - 1.6e-13 50.9 0.1 3.9e-13 49.7 0.1 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 AIN96587.1 - 1.2e-09 38.4 0.0 3.8e-09 36.8 0.0 1.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 AIN96587.1 - 0.0026 17.0 0.6 0.0045 16.2 0.6 1.3 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase DEAD PF00270.29 AIN96587.1 - 0.025 14.3 0.0 0.15 11.8 0.0 2.3 2 1 0 2 2 2 0 DEAD/DEAH box helicase DUF2095 PF09868.9 AIN96587.1 - 0.033 14.2 0.0 0.093 12.7 0.0 1.7 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2095) DUF4279 PF14106.6 AIN96587.1 - 0.088 13.0 0.0 0.26 11.5 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4279) cNMP_binding PF00027.29 AIN96588.1 - 0.0017 18.4 0.0 0.32 11.1 0.0 3.0 3 1 0 3 3 3 2 Cyclic nucleotide-binding domain Arf PF00025.21 AIN96589.1 - 0.00042 19.8 0.0 0.00096 18.6 0.0 1.5 1 1 0 1 1 1 1 ADP-ribosylation factor family AAA_28 PF13521.6 AIN96589.1 - 0.012 15.9 0.2 0.019 15.2 0.2 1.4 1 0 0 1 1 1 0 AAA domain DHHC PF01529.20 AIN96590.1 - 2.9e-23 82.5 13.9 2.9e-23 82.5 13.9 2.2 2 0 0 2 2 2 1 DHHC palmitoyltransferase PIG-P PF08510.12 AIN96590.1 - 0.1 12.5 1.3 9.3 6.2 0.0 2.8 2 1 1 3 3 3 0 PIG-P Wzy_C PF04932.15 AIN96590.1 - 2.2 7.9 8.0 0.72 9.5 2.1 2.1 2 0 0 2 2 2 0 O-Antigen ligase PRP1_N PF06424.12 AIN96591.1 - 0.14 12.6 0.2 0.14 12.6 0.2 1.7 2 0 0 2 2 2 0 PRP1 splicing factor, N-terminal DnaJ PF00226.31 AIN96592.1 - 0.002 18.2 0.0 0.0048 17.0 0.0 1.6 1 0 0 1 1 1 1 DnaJ domain CH PF00307.31 AIN96593.1 - 0.012 15.7 0.0 0.039 14.1 0.0 1.8 1 0 0 1 1 1 0 Calponin homology (CH) domain Phage_GP20 PF06810.11 AIN96593.1 - 0.06 13.1 4.8 0.13 12.1 4.8 1.5 1 0 0 1 1 1 0 Phage minor structural protein GP20 DUF4061 PF13270.6 AIN96593.1 - 0.075 13.4 2.4 2 8.8 2.6 3.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4061) GrpE PF01025.19 AIN96593.1 - 0.67 9.6 5.0 2 8.0 5.0 1.7 1 0 0 1 1 1 0 GrpE DnaJ PF00226.31 AIN96594.1 - 1.4e-12 47.6 0.9 2.6e-12 46.7 0.9 1.5 1 0 0 1 1 1 1 DnaJ domain IU_nuc_hydro PF01156.19 AIN96596.1 - 3.1e-68 230.6 0.0 3.8e-68 230.3 0.0 1.0 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase MOZ_SAS PF01853.18 AIN96597.1 - 3.9e-62 209.1 0.0 6.4e-62 208.4 0.0 1.3 1 0 0 1 1 1 1 MOZ/SAS family Tudor-knot PF11717.8 AIN96597.1 - 1e-08 35.0 0.5 3.7e-08 33.1 0.1 2.0 2 0 0 2 2 2 1 RNA binding activity-knot of a chromodomain zf-MYST PF17772.1 AIN96597.1 - 1e-08 34.6 0.5 5.2e-05 22.8 0.1 2.5 2 0 0 2 2 2 2 MYST family zinc finger domain Acetyltransf_7 PF13508.7 AIN96597.1 - 0.0011 19.3 0.0 0.0033 17.8 0.0 1.8 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 AIN96597.1 - 0.036 14.3 0.0 0.093 13.0 0.0 1.7 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family zf-Di19 PF05605.12 AIN96597.1 - 0.25 11.7 5.2 1.9 8.8 0.8 2.5 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding Ribosomal_L12 PF00542.19 AIN96598.1 - 1.5e-16 60.5 3.4 1.5e-16 60.5 3.4 1.7 2 0 0 2 2 2 1 Ribosomal protein L7/L12 C-terminal domain PSII_Pbs27 PF13326.6 AIN96598.1 - 0.022 15.1 5.7 0.07 13.5 2.5 2.1 2 0 0 2 2 2 0 Photosystem II Pbs27 Ribosomal_L12_N PF16320.5 AIN96598.1 - 1.8 8.4 0.0 1.8 8.4 0.0 2.9 3 0 0 3 3 3 0 Ribosomal protein L7/L12 dimerisation domain Chromo PF00385.24 AIN96599.1 - 0.0039 17.1 0.1 0.0069 16.3 0.1 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Methyltransf_32 PF13679.6 AIN96599.1 - 2.3 8.2 3.9 11 6.0 3.9 2.1 1 1 0 1 1 1 0 Methyltransferase domain Thioredoxin_8 PF13905.6 AIN96601.1 - 2.6e-08 34.1 0.1 3.9e-08 33.5 0.1 1.3 1 0 0 1 1 1 1 Thioredoxin-like Redoxin PF08534.10 AIN96601.1 - 0.00062 19.5 0.1 0.00072 19.3 0.1 1.2 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 AIN96601.1 - 0.00065 19.6 0.0 0.00089 19.2 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family BBIP10 PF14777.6 AIN96602.1 - 3.4e-21 74.6 3.8 5.9e-21 73.8 3.8 1.3 1 0 0 1 1 1 1 Cilia BBSome complex subunit 10 DUF3275 PF11679.8 AIN96602.1 - 0.65 9.9 2.1 1.1 9.2 2.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3275) DUF4201 PF13870.6 AIN96603.1 - 3.1e-30 105.2 8.8 3.1e-30 105.2 8.8 2.6 2 1 1 3 3 3 1 Domain of unknown function (DUF4201) bZIP_1 PF00170.21 AIN96603.1 - 0.053 13.6 1.1 0.053 13.6 1.1 3.8 4 0 0 4 4 4 0 bZIP transcription factor Csm1_N PF18504.1 AIN96603.1 - 0.25 11.7 18.5 0.37 11.2 2.7 4.3 3 1 1 4 4 4 0 Csm1 N-terminal domain MCM_N PF14551.6 AIN96603.1 - 0.45 11.1 3.1 2.7 8.6 0.1 2.9 3 0 0 3 3 3 0 MCM N-terminal domain APC_N_CC PF16689.5 AIN96603.1 - 3.1 7.9 6.2 6.4 6.9 2.7 3.0 2 1 1 3 3 3 0 Coiled-coil N-terminus of APC, dimerisation domain PX PF00787.24 AIN96604.1 - 1.3e-09 38.0 0.2 7.5e-09 35.6 0.0 2.3 3 0 0 3 3 3 1 PX domain Sec5 PF15469.6 AIN96605.1 - 6.1e-05 22.9 0.0 0.00013 21.9 0.0 1.5 1 0 0 1 1 1 1 Exocyst complex component Sec5 HIT PF01230.23 AIN96606.1 - 2.6e-23 82.6 0.0 3.4e-23 82.2 0.0 1.2 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.8 AIN96606.1 - 1.6e-12 47.9 0.0 2.2e-12 47.5 0.0 1.1 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding CwfJ_C_1 PF04677.15 AIN96606.1 - 0.00063 19.6 1.1 0.0018 18.1 1.1 1.8 1 1 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 RF3_C PF16658.5 AIN96606.1 - 0.11 12.3 0.0 0.2 11.5 0.0 1.3 1 0 0 1 1 1 0 Class II release factor RF3, C-terminal domain YcxB PF14317.6 AIN96606.1 - 0.12 12.2 0.0 23 4.8 0.0 2.8 2 1 1 3 3 3 0 YcxB-like protein TRAP-gamma PF07074.12 AIN96607.1 - 1.9e-08 34.1 2.9 0.00054 19.5 0.2 2.1 2 0 0 2 2 2 2 Translocon-associated protein, gamma subunit (TRAP-gamma) DUF4386 PF14329.6 AIN96607.1 - 0.026 14.4 1.3 0.043 13.7 1.3 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4386) VWA_3 PF13768.6 AIN96608.1 - 2.5e-08 34.0 0.1 6.1e-08 32.8 0.1 1.6 1 0 0 1 1 1 1 von Willebrand factor type A domain VIT_2 PF13757.6 AIN96608.1 - 0.0006 19.7 0.1 0.002 18.0 0.1 1.9 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain Epimerase PF01370.21 AIN96610.1 - 9.6e-09 35.0 0.2 0.0041 16.6 0.1 2.4 2 1 0 2 2 2 2 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 AIN96610.1 - 0.00019 20.7 0.1 0.017 14.3 0.0 2.3 2 1 0 2 2 2 2 Male sterility protein NAD_binding_10 PF13460.6 AIN96610.1 - 0.00026 20.9 1.0 0.11 12.4 0.2 2.3 2 0 0 2 2 2 2 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 AIN96610.1 - 0.008 15.6 0.4 0.027 13.8 0.0 1.9 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 AIN96610.1 - 0.036 13.2 0.2 5.3 6.1 0.0 2.5 2 1 0 2 2 2 0 RmlD substrate binding domain Proteasome PF00227.26 AIN96612.1 - 6.6e-51 172.5 0.0 8.8e-51 172.1 0.0 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 AIN96612.1 - 4.3e-13 48.7 0.3 7.3e-13 47.9 0.3 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature DUF2064 PF09837.9 AIN96612.1 - 0.09 12.6 0.0 0.25 11.2 0.0 1.8 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2064) AA_permease_2 PF13520.6 AIN96613.1 - 6.1e-35 120.9 39.7 9.3e-35 120.3 39.5 1.4 1 1 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 AIN96613.1 - 4.8e-10 38.6 37.4 1.6e-09 36.9 37.4 1.8 1 1 0 1 1 1 1 Amino acid permease Aa_trans PF01490.18 AIN96614.1 - 3.3e-24 85.4 18.5 4.5e-24 84.9 18.5 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein IPK PF03770.16 AIN96615.1 - 4.7e-42 144.1 0.1 9.9e-42 143.0 0.1 1.6 1 0 0 1 1 1 1 Inositol polyphosphate kinase Thr_synth_N PF14821.6 AIN96616.1 - 8.8e-13 48.3 0.1 3e-12 46.6 0.0 2.0 2 0 0 2 2 2 1 Threonine synthase N terminus PALP PF00291.25 AIN96616.1 - 3e-10 40.0 0.0 6.4e-10 38.9 0.0 1.5 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme zf-CW PF07496.15 AIN96617.1 - 0.00044 20.2 3.0 0.00044 20.2 3.0 1.8 2 0 0 2 2 2 1 CW-type Zinc Finger Bromodomain PF00439.25 AIN96617.1 - 0.1 12.7 0.0 0.97 9.5 0.0 2.1 1 1 0 1 1 1 0 Bromodomain Choline_transpo PF04515.12 AIN96619.1 - 3.3e-52 177.7 40.7 3.3e-52 177.7 40.7 1.7 2 0 0 2 2 2 1 Plasma-membrane choline transporter ATP-synt_D PF01813.17 AIN96620.1 - 0.08 12.8 0.1 10 5.9 0.0 2.1 2 0 0 2 2 2 0 ATP synthase subunit D UTP25 PF06862.12 AIN96621.1 - 1.6e-110 370.2 0.9 2.1e-101 340.0 0.1 2.1 2 0 0 2 2 2 2 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 Dzip-like_N PF13815.6 AIN96622.1 - 3e-40 136.8 1.8 3e-40 136.8 1.8 2.1 3 0 0 3 3 3 1 Iguana/Dzip1-like DAZ-interacting protein N-terminal zf-Di19 PF05605.12 AIN96622.1 - 0.0005 20.3 0.9 0.00072 19.8 0.1 1.7 2 0 0 2 2 2 1 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_4 PF13894.6 AIN96622.1 - 0.011 16.5 1.0 0.025 15.4 1.0 1.6 1 0 0 1 1 1 0 C2H2-type zinc finger zf-C2H2_2 PF12756.7 AIN96622.1 - 0.072 13.4 0.5 0.39 11.1 0.1 2.1 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) HCR PF07111.12 AIN96622.1 - 0.083 10.9 3.8 3.2 5.7 1.0 2.3 2 0 0 2 2 2 0 Alpha helical coiled-coil rod protein (HCR) zf-C2H2 PF00096.26 AIN96622.1 - 0.4 11.2 1.3 0.87 10.2 1.3 1.6 1 0 0 1 1 1 0 Zinc finger, C2H2 type mRNA_triPase PF02940.15 AIN96623.1 - 5e-07 29.7 0.0 0.021 14.6 0.0 2.9 3 0 0 3 3 3 2 mRNA capping enzyme, beta chain Pyr_redox_2 PF07992.14 AIN96624.1 - 3.1e-16 59.5 0.0 1.2e-14 54.3 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 AIN96624.1 - 2.3e-09 37.7 0.0 6.9e-06 26.5 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 AIN96624.1 - 7.9e-07 28.4 0.0 0.00081 18.5 0.0 3.1 3 0 0 3 3 3 1 Lycopene cyclase protein NAD_binding_9 PF13454.6 AIN96624.1 - 3.6e-06 27.1 0.0 0.023 14.7 0.0 3.3 3 0 0 3 3 3 2 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 AIN96624.1 - 1.3e-05 25.3 0.8 0.079 13.2 0.0 2.9 3 0 0 3 3 3 2 NAD(P)-binding Rossmann-like domain DAO PF01266.24 AIN96624.1 - 2.1e-05 24.3 0.0 0.073 12.6 0.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase K_oxygenase PF13434.6 AIN96624.1 - 0.00073 18.8 0.0 0.003 16.8 0.0 1.9 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Thi4 PF01946.17 AIN96624.1 - 0.0012 18.2 0.0 0.019 14.2 0.0 2.2 2 0 0 2 2 2 1 Thi4 family GIDA PF01134.22 AIN96624.1 - 0.0065 15.6 0.0 2 7.4 0.0 2.8 3 0 0 3 3 3 2 Glucose inhibited division protein A FAD_binding_3 PF01494.19 AIN96624.1 - 0.034 13.4 0.1 0.29 10.3 0.0 2.0 2 0 0 2 2 2 0 FAD binding domain NAD_binding_7 PF13241.6 AIN96624.1 - 0.051 14.0 0.0 15 6.1 0.0 2.4 2 0 0 2 2 2 0 Putative NAD(P)-binding Trp_halogenase PF04820.14 AIN96624.1 - 0.16 10.8 0.0 11 4.7 0.0 2.4 3 0 0 3 3 3 0 Tryptophan halogenase CS PF04969.16 AIN96625.1 - 1.5e-15 57.9 0.0 2.6e-15 57.2 0.0 1.4 1 0 0 1 1 1 1 CS domain Nudc_N PF14050.6 AIN96625.1 - 6.2e-14 51.7 0.2 1.4e-13 50.6 0.2 1.6 1 0 0 1 1 1 1 N-terminal conserved domain of Nudc. Borrelia_P83 PF05262.11 AIN96625.1 - 0.0001 20.9 14.3 0.00013 20.6 14.3 1.1 1 0 0 1 1 1 1 Borrelia P83/100 protein Hid1 PF12722.7 AIN96625.1 - 0.018 13.2 2.1 0.023 12.9 2.1 1.3 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Cys_Met_Meta_PP PF01053.20 AIN96626.1 - 3e-115 384.8 0.0 3.7e-115 384.5 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 AIN96626.1 - 0.00059 19.1 0.0 0.0011 18.3 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 AIN96626.1 - 0.33 10.2 1.3 0.45 9.8 0.2 1.8 2 1 0 2 2 2 0 Beta-eliminating lyase UDPGT PF00201.18 AIN96627.1 - 2.6e-29 102.4 0.0 5e-29 101.4 0.0 1.5 1 1 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Amastin PF07344.11 AIN96628.1 - 1e-07 31.9 13.5 1e-07 31.9 13.5 2.1 1 1 1 2 2 2 1 Amastin surface glycoprotein Amastin PF07344.11 AIN96629.1 - 1.4e-07 31.5 13.9 1.4e-07 31.5 13.9 2.1 1 1 0 2 2 2 1 Amastin surface glycoprotein SH3_9 PF14604.6 AIN96630.1 - 0.012 15.5 0.0 0.15 12.0 0.0 2.6 2 1 0 2 2 2 0 Variant SH3 domain Hemerythrin PF01814.23 AIN96630.1 - 0.071 13.7 2.5 0.34 11.5 0.0 3.0 3 0 0 3 3 3 0 Hemerythrin HHE cation binding domain DUF5082 PF16888.5 AIN96630.1 - 0.099 12.9 0.7 1.9 8.8 0.5 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF5082) RPW8 PF05659.11 AIN96630.1 - 0.17 11.6 0.3 27 4.4 0.0 2.7 3 0 0 3 3 3 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 Spc7 PF08317.11 AIN96630.1 - 0.47 9.3 8.3 7 5.4 0.0 3.3 3 1 0 3 3 3 0 Spc7 kinetochore protein SRC-1 PF08832.10 AIN96630.1 - 0.83 10.8 0.0 0.83 10.8 0.0 4.1 4 1 0 4 4 4 0 Steroid receptor coactivator UPF0242 PF06785.11 AIN96630.1 - 1.8 8.7 7.8 4.5 7.3 4.9 2.5 2 1 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Nup54 PF13874.6 AIN96630.1 - 6.1 6.9 10.7 0.74 9.9 0.5 3.4 3 1 0 3 3 3 0 Nucleoporin complex subunit 54 zf-C4H2 PF10146.9 AIN96630.1 - 7 6.9 7.6 23 5.2 0.3 3.4 3 2 1 4 4 4 0 Zinc finger-containing protein FA_desaturase PF00487.24 AIN96631.1 - 5e-14 52.7 24.3 1.1e-13 51.6 24.3 1.6 1 1 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.28 AIN96631.1 - 6e-09 35.9 0.0 6.4e-08 32.6 0.0 2.2 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain 5TM-5TMR_LYT PF07694.12 AIN96631.1 - 0.02 14.4 2.5 0.042 13.4 0.5 2.2 2 0 0 2 2 2 0 5TMR of 5TMR-LYT Collectrin PF16959.5 AIN96631.1 - 0.033 13.9 0.1 0.083 12.7 0.1 1.6 1 0 0 1 1 1 0 Renal amino acid transporter MerC PF03203.14 AIN96631.1 - 0.32 11.5 6.3 0.12 12.8 1.0 2.4 2 0 0 2 2 2 0 MerC mercury resistance protein Ion_trans_2 PF07885.16 AIN96633.1 - 1.1e-07 31.7 6.3 1.1e-07 31.7 6.3 2.1 2 0 0 2 2 2 1 Ion channel IQ PF00612.27 AIN96633.1 - 0.069 13.0 1.5 0.11 12.4 0.1 2.2 2 0 0 2 2 2 0 IQ calmodulin-binding motif Ion_trans_2 PF07885.16 AIN96634.1 - 4.1e-10 39.5 7.4 4.1e-10 39.5 7.4 2.3 2 0 0 2 2 2 1 Ion channel Lig_chan PF00060.26 AIN96634.1 - 0.012 15.5 3.5 0.012 15.5 3.5 2.1 2 1 0 2 2 2 0 Ligand-gated ion channel Ion_trans PF00520.31 AIN96634.1 - 0.07 12.3 21.4 0.32 10.2 21.4 2.0 1 1 0 1 1 1 0 Ion transport protein T2SSM PF04612.12 AIN96635.1 - 0.00032 20.8 0.8 0.0019 18.3 0.0 2.4 3 0 0 3 3 3 1 Type II secretion system (T2SS), protein M DUF3496 PF12001.8 AIN96635.1 - 0.0039 17.5 0.2 0.0088 16.4 0.2 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3496) TSC22 PF01166.18 AIN96635.1 - 0.11 12.8 0.9 4.4 7.7 0.1 2.4 2 0 0 2 2 2 0 TSC-22/dip/bun family WD40 PF00400.32 AIN96637.1 - 3e-22 78.5 20.7 0.0027 18.5 0.0 10.2 11 0 0 11 11 11 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 AIN96637.1 - 1.8e-07 31.4 0.0 38 4.7 0.0 8.0 7 1 1 8 8 8 2 Anaphase-promoting complex subunit 4 WD40 domain Utp12 PF04003.12 AIN96637.1 - 1.5e-06 28.5 0.2 2.9e-06 27.5 0.2 1.5 1 0 0 1 1 1 1 Dip2/Utp12 Family Complex1_LYR PF05347.15 AIN96638.1 - 0.00098 19.1 0.4 0.0017 18.4 0.4 1.4 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 AIN96638.1 - 0.076 13.8 0.2 0.13 13.0 0.2 1.4 1 0 0 1 1 1 0 Complex1_LYR-like DUF3678 PF12435.8 AIN96639.1 - 0.025 13.9 0.4 0.18 11.2 0.4 2.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3678) SpoU_methylase PF00588.19 AIN96640.1 - 2.5e-10 40.7 0.0 0.00022 21.4 0.0 2.4 2 0 0 2 2 2 2 SpoU rRNA Methylase family Nrap_D2 PF17403.2 AIN96640.1 - 0.026 14.3 0.0 0.048 13.4 0.0 1.3 1 0 0 1 1 1 0 Nrap protein PAP/OAS-like domain Spt5_N PF11942.8 AIN96641.1 - 0.0052 17.7 5.0 0.0052 17.7 5.0 2.6 3 0 0 3 3 3 1 Spt5 transcription elongation factor, acidic N-terminal CDC45 PF02724.14 AIN96641.1 - 4.9 5.3 7.4 0.59 8.4 2.2 1.8 2 0 0 2 2 2 0 CDC45-like protein EZH2_N PF18601.1 AIN96642.1 - 0.061 13.6 0.0 0.14 12.5 0.0 1.5 1 0 0 1 1 1 0 EZH2 N-terminal domain zf-LSD1 PF06943.12 AIN96643.1 - 1.7e-07 30.9 8.6 1.7e-07 30.9 8.6 3.5 4 1 0 4 4 4 1 LSD1 zinc finger zf-NADH-PPase PF09297.11 AIN96643.1 - 0.2 11.3 6.7 0.18 11.5 3.9 2.3 2 0 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain DZR PF12773.7 AIN96643.1 - 0.34 11.0 10.4 0.071 13.2 4.7 2.4 1 1 1 2 2 2 0 Double zinc ribbon ELO PF01151.18 AIN96644.1 - 1.2e-39 136.4 11.2 1.4e-39 136.2 11.2 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family ELO PF01151.18 AIN96645.1 - 1.6e-65 221.2 17.5 1.8e-65 221.0 17.5 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family ELO PF01151.18 AIN96646.1 - 6.9e-62 209.2 14.0 8e-62 209.0 14.0 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family ELO PF01151.18 AIN96647.1 - 7.9e-63 212.3 13.3 9.1e-63 212.1 13.3 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family ELO PF01151.18 AIN96648.1 - 2e-69 233.9 4.8 2.3e-69 233.7 4.8 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family ELO PF01151.18 AIN96649.1 - 7.2e-81 271.4 21.5 8.5e-81 271.2 21.5 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family DUF1980 PF09323.10 AIN96649.1 - 0.063 13.2 1.3 0.1 12.5 1.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) CrgA PF06781.12 AIN96649.1 - 0.14 12.3 2.1 0.41 10.7 0.1 2.4 2 0 0 2 2 2 0 Cell division protein CrgA ELO PF01151.18 AIN96650.1 - 2.1e-84 283.0 17.1 2.6e-84 282.6 17.1 1.1 1 0 0 1 1 1 1 GNS1/SUR4 family ELO PF01151.18 AIN96651.1 - 5.1e-68 229.3 23.2 6e-68 229.1 23.2 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family ELO PF01151.18 AIN96652.1 - 1.7e-71 240.6 24.1 2.1e-71 240.4 24.1 1.1 1 0 0 1 1 1 1 GNS1/SUR4 family DUF2670 PF10875.8 AIN96652.1 - 3.4 7.8 5.4 13 5.9 0.0 3.2 2 1 0 2 2 2 0 Protein of unknown function (DUF2670) ELO PF01151.18 AIN96653.1 - 2.6e-79 266.3 21.1 3.2e-79 266.0 21.1 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family Ribosomal_L21p PF00829.21 AIN96656.1 - 1.7e-19 70.0 0.0 2.2e-19 69.6 0.0 1.2 1 0 0 1 1 1 1 Ribosomal prokaryotic L21 protein PsbP PF01789.16 AIN96656.1 - 0.035 14.3 0.1 0.065 13.4 0.1 1.4 1 0 0 1 1 1 0 PsbP Pox_A_type_inc PF04508.12 AIN96657.1 - 0.35 10.8 4.1 2 8.4 4.1 2.4 1 0 0 1 1 1 0 Viral A-type inclusion protein repeat DUF1682 PF07946.14 AIN96658.1 - 0.041 13.1 1.5 0.069 12.3 1.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) TRAP_alpha PF03896.16 AIN96658.1 - 0.076 12.2 0.6 0.14 11.3 0.6 1.4 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit DUF4201 PF13870.6 AIN96659.1 - 2.3e-30 105.7 16.6 2.3e-30 105.7 16.6 3.2 4 0 0 4 4 4 1 Domain of unknown function (DUF4201) JIP_LZII PF16471.5 AIN96659.1 - 0.031 14.4 1.4 0.031 14.4 1.4 5.1 4 2 1 5 5 5 0 JNK-interacting protein leucine zipper II SlyX PF04102.12 AIN96659.1 - 0.049 14.3 0.0 0.049 14.3 0.0 6.6 5 3 3 8 8 8 0 SlyX Phycoerythr_ab PF02972.14 AIN96659.1 - 0.8 9.6 2.8 2.6 7.9 0.7 2.8 2 0 0 2 2 2 0 Phycoerythrin, alpha/beta chain DUF16 PF01519.16 AIN96659.1 - 4.8 7.7 0.0 4.8 7.7 0.0 5.5 4 1 2 6 6 6 0 Protein of unknown function DUF16 Pkinase PF00069.25 AIN96660.1 - 1.1e-41 143.0 0.0 1.2e-22 80.5 0.0 2.8 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 AIN96660.1 - 3.2e-12 46.3 0.0 9.8e-08 31.6 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.23 AIN96660.1 - 0.00043 20.3 0.0 0.00076 19.5 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 AIN96660.1 - 0.035 13.7 0.0 0.057 13.0 0.0 1.2 1 0 0 1 1 1 0 RIO1 family Choline_kinase PF01633.20 AIN96660.1 - 0.05 13.2 0.0 0.077 12.6 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase SNF2_N PF00176.23 AIN96661.1 - 3.4e-58 197.0 0.0 7.7e-58 195.9 0.0 1.6 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 AIN96661.1 - 9e-20 71.1 0.0 8.6e-19 67.9 0.0 2.6 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 AIN96661.1 - 1.8e-08 34.6 0.0 5.5e-08 33.0 0.0 1.9 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit YebO PF13974.6 AIN96661.1 - 0.78 9.9 4.7 0.3 11.2 0.2 2.7 2 0 0 2 2 2 0 YebO-like protein AChE_tetra PF08674.10 AIN96661.1 - 2.3 8.0 3.7 0.95 9.2 0.1 2.2 2 0 0 2 2 2 0 Acetylcholinesterase tetramerisation domain DUF1935 PF09149.10 AIN96662.1 - 1.8e-39 134.3 0.3 2e-39 134.1 0.3 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1935) PP2C PF00481.21 AIN96665.1 - 4.8e-48 164.0 0.0 1.8e-47 162.1 0.0 1.9 1 1 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 AIN96665.1 - 7.8e-07 28.9 0.1 7.8e-07 28.9 0.1 2.7 2 1 0 2 2 2 1 Protein phosphatase 2C CAP_N PF01213.19 AIN96665.1 - 8.4 5.8 5.4 23 4.4 0.7 2.3 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal GSH_synth_ATP PF03917.17 AIN96666.1 - 1.3e-72 244.7 0.0 1.8e-72 244.2 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic glutathione synthase, ATP binding domain GSH_synthase PF03199.15 AIN96666.1 - 6.8e-31 106.8 0.1 1.4e-30 105.8 0.1 1.5 1 0 0 1 1 1 1 Eukaryotic glutathione synthase DNA_pol_A PF00476.20 AIN96667.1 - 1e-39 136.7 0.0 1.6e-38 132.8 0.0 2.4 2 1 0 2 2 2 1 DNA polymerase family A Pesticin PF16754.5 AIN96668.1 - 0.11 12.5 0.1 8.2 6.4 0.0 2.4 2 0 0 2 2 2 0 Bacterial toxin homologue of phage lysozyme, C-term SlyX PF04102.12 AIN96668.1 - 0.13 12.9 9.7 11 6.7 0.0 4.6 3 1 1 4 4 4 0 SlyX DUF4315 PF14193.6 AIN96668.1 - 0.35 10.9 2.7 0.44 10.6 0.5 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4315) Serine_rich PF08824.10 AIN96668.1 - 1.8 8.5 8.0 8.4 6.4 0.3 3.3 3 0 0 3 3 3 0 Serine rich protein interaction domain PBP1_TM PF14812.6 AIN96669.1 - 7.1 7.1 8.1 18 5.8 8.1 1.6 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Ribosomal_L16 PF00252.18 AIN96670.1 - 3e-16 59.6 0.0 3.6e-16 59.4 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e PAP_assoc PF03828.19 AIN96671.1 - 1.8e-16 60.1 0.0 3.2e-11 43.3 0.0 2.9 3 0 0 3 3 3 2 Cid1 family poly A polymerase NTP_transf_2 PF01909.23 AIN96671.1 - 0.051 13.9 0.0 0.79 10.1 0.0 2.3 2 0 0 2 2 2 0 Nucleotidyltransferase domain zf-MYST PF17772.1 AIN96671.1 - 0.071 12.7 0.1 0.14 11.8 0.1 1.4 1 0 0 1 1 1 0 MYST family zinc finger domain PRK PF00485.18 AIN96672.1 - 8.3e-05 22.4 0.0 0.029 14.1 0.0 2.2 2 0 0 2 2 2 2 Phosphoribulokinase / Uridine kinase family AAA_18 PF13238.6 AIN96672.1 - 0.00018 22.1 0.0 0.18 12.3 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.6 AIN96672.1 - 0.06 12.9 0.0 0.098 12.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 AIN96672.1 - 0.066 12.5 0.2 0.13 11.5 0.0 1.5 2 0 0 2 2 2 0 Zeta toxin dNK PF01712.19 AIN96672.1 - 0.076 12.9 0.0 9 6.1 0.0 2.2 2 0 0 2 2 2 0 Deoxynucleoside kinase MMR_HSR1 PF01926.23 AIN96672.1 - 0.11 12.6 0.0 0.24 11.5 0.0 1.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase RNA_helicase PF00910.22 AIN96672.1 - 0.13 12.6 0.0 0.24 11.8 0.0 1.4 1 0 0 1 1 1 0 RNA helicase ABC_tran PF00005.27 AIN96672.1 - 0.15 12.6 0.0 0.24 11.9 0.0 1.3 1 0 0 1 1 1 0 ABC transporter Na_H_Exchanger PF00999.21 AIN96673.1 - 1.7e-18 66.6 24.6 2.9e-18 65.8 24.6 1.3 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Mito_carr PF00153.27 AIN96674.1 - 9.8e-26 89.5 0.4 1.4e-11 44.1 0.0 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein Mito_carr PF00153.27 AIN96675.1 - 1.3e-06 28.2 0.0 0.01 15.7 0.0 3.5 3 1 0 3 3 3 3 Mitochondrial carrier protein Sulfotransfer_3 PF13469.6 AIN96678.1 - 1.1e-05 26.0 0.0 1.8e-05 25.2 0.0 1.4 1 0 0 1 1 1 1 Sulfotransferase family SRA1 PF07304.11 AIN96678.1 - 0.017 14.9 0.0 0.033 14.0 0.0 1.4 1 0 0 1 1 1 0 Steroid receptor RNA activator (SRA1) DUF202 PF02656.15 AIN96679.1 - 3.8e-16 59.3 0.7 1.7e-15 57.2 0.1 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF202) COQ9 PF08511.11 AIN96681.1 - 1.8e-05 24.4 0.0 0.00046 19.9 0.0 2.4 2 0 0 2 2 2 1 COQ9 AAA_6 PF12774.7 AIN96682.1 - 3.2e-141 470.0 1.2 3e-139 463.6 0.0 3.5 3 0 0 3 3 3 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 AIN96682.1 - 1.2e-108 363.8 0.2 1.2e-108 363.8 0.2 2.9 3 0 0 3 3 3 1 Dynein heavy chain, N-terminal region 2 AAA_8 PF12780.7 AIN96682.1 - 8.4e-93 310.4 0.0 2.5e-92 308.9 0.0 1.9 1 0 0 1 1 1 1 P-loop containing dynein motor region D4 Dynein_C PF18199.1 AIN96682.1 - 3.2e-81 272.9 1.4 9.4e-81 271.4 0.0 2.6 3 0 0 3 3 3 1 Dynein heavy chain C-terminal domain AAA_9 PF12781.7 AIN96682.1 - 8.9e-72 240.8 0.7 8.9e-72 240.8 0.7 2.4 3 0 0 3 3 3 1 ATP-binding dynein motor region AAA_7 PF12775.7 AIN96682.1 - 1.4e-54 184.3 2.0 1e-49 168.5 0.0 4.4 4 0 0 4 4 4 2 P-loop containing dynein motor region MT PF12777.7 AIN96682.1 - 3.4e-42 144.7 3.6 3.4e-42 144.7 3.6 2.1 3 0 0 3 3 3 1 Microtubule-binding stalk of dynein motor Dynein_heavy PF03028.15 AIN96682.1 - 2.3e-39 134.2 0.0 1.5e-36 125.1 0.0 3.5 3 0 0 3 3 3 1 Dynein heavy chain region D6 P-loop domain AAA_lid_11 PF18198.1 AIN96682.1 - 2e-25 89.5 0.0 1.2e-24 86.9 0.0 2.4 2 0 0 2 2 2 1 Dynein heavy chain AAA lid domain AAA_5 PF07728.14 AIN96682.1 - 4.8e-18 65.5 3.6 5.7e-05 23.1 0.0 6.2 6 1 0 6 6 6 4 AAA domain (dynein-related subfamily) Dynein_AAA_lid PF17852.1 AIN96682.1 - 5.8e-18 65.2 0.2 2e-16 60.2 0.2 3.3 2 1 0 2 2 2 1 Dynein heavy chain AAA lid domain AAA_lid_1 PF17857.1 AIN96682.1 - 2.9e-17 62.7 0.0 1.1e-16 60.8 0.0 2.0 1 0 0 1 1 1 1 AAA+ lid domain AAA_22 PF13401.6 AIN96682.1 - 1.2e-05 25.6 15.5 0.066 13.5 0.0 7.7 6 1 1 7 7 7 1 AAA domain AAA_16 PF13191.6 AIN96682.1 - 0.00029 21.3 16.8 0.51 10.7 0.0 6.7 6 1 0 6 6 4 2 AAA ATPase domain AAA PF00004.29 AIN96682.1 - 0.00059 20.3 1.2 2 8.8 0.0 4.4 4 0 0 4 4 4 1 ATPase family associated with various cellular activities (AAA) T2SSE PF00437.20 AIN96682.1 - 0.00076 18.6 0.2 0.1 11.7 0.0 3.2 3 0 0 3 3 3 1 Type II/IV secretion system protein DUF815 PF05673.13 AIN96682.1 - 0.00088 18.5 0.2 1.1 8.4 0.0 3.3 3 0 0 3 3 3 2 Protein of unknown function (DUF815) AAA_29 PF13555.6 AIN96682.1 - 0.0022 17.7 2.2 4.7 7.0 0.1 3.8 3 0 0 3 3 3 1 P-loop containing region of AAA domain AAA_18 PF13238.6 AIN96682.1 - 0.011 16.2 1.4 5.1 7.7 0.0 4.4 4 0 0 4 4 4 0 AAA domain NKAIN PF05640.14 AIN96682.1 - 0.081 12.2 0.0 0.17 11.1 0.0 1.5 1 0 0 1 1 1 0 Na,K-Atpase Interacting protein Mg_chelatase PF01078.21 AIN96682.1 - 0.09 12.1 0.8 32 3.8 0.0 3.9 4 0 0 4 4 4 0 Magnesium chelatase, subunit ChlI RsgA_GTPase PF03193.16 AIN96682.1 - 0.11 12.4 1.1 5 7.0 0.1 3.2 3 0 0 3 3 3 0 RsgA GTPase LMBR1 PF04791.16 AIN96682.1 - 0.37 9.7 1.7 0.76 8.6 1.7 1.4 1 0 0 1 1 1 0 LMBR1-like membrane protein DASH_Spc34 PF08657.10 AIN96682.1 - 1 9.1 5.1 2.2 8.0 4.0 2.1 2 0 0 2 2 2 0 DASH complex subunit Spc34 NBP1 PF08537.10 AIN96682.1 - 1.5 8.1 4.0 4.4 6.6 4.0 1.7 1 0 0 1 1 1 0 Fungal Nap binding protein NBP1 DUF724 PF05266.14 AIN96682.1 - 2.2 8.1 10.9 26 4.6 6.3 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF724) Pkinase PF00069.25 AIN96683.1 - 1.3e-43 149.3 0.0 1.3e-42 146.0 0.0 2.5 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 AIN96683.1 - 8.1e-17 61.4 0.0 9.4e-16 57.9 0.0 2.1 2 0 0 2 2 2 1 Protein tyrosine kinase PBP_sp32 PF07222.12 AIN96683.1 - 1.3 8.5 5.0 2.9 7.3 5.0 1.6 1 0 0 1 1 1 0 Proacrosin binding protein sp32 LST1 PF05083.13 AIN96684.1 - 2.1 8.7 4.1 12 6.2 4.1 2.2 2 1 0 2 2 2 0 LST-1 protein PQ-loop PF04193.14 AIN96685.1 - 7.7e-26 89.7 5.9 1.6e-12 47.0 0.3 2.5 2 0 0 2 2 2 2 PQ loop repeat Kinesin PF00225.23 AIN96686.1 - 1.7e-76 257.3 0.0 2.1e-76 257.0 0.0 1.1 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 AIN96686.1 - 0.031 14.2 0.0 0.084 12.8 0.0 1.7 1 0 0 1 1 1 0 Microtubule binding Kinesin_assoc PF16183.5 AIN96686.1 - 0.04 14.1 0.7 0.073 13.2 0.1 1.7 2 0 0 2 2 2 0 Kinesin-associated DUF3734 PF12536.8 AIN96686.1 - 0.18 12.1 1.6 11 6.4 0.1 2.4 2 0 0 2 2 2 0 Patatin phospholipase Prefoldin_2 PF01920.20 AIN96687.1 - 0.0049 16.8 34.2 0.97 9.4 0.4 6.1 1 1 6 7 7 7 4 Prefoldin subunit Tim17 PF02466.19 AIN96687.1 - 0.028 14.8 0.1 14 6.1 0.1 3.6 1 1 1 2 2 2 0 Tim17/Tim22/Tim23/Pmp24 family DUF240 PF03086.14 AIN96687.1 - 0.085 12.8 3.9 7 6.6 0.1 3.2 1 1 2 3 3 3 0 Domain of unknown function (DUF240) DUF2316 PF10078.9 AIN96687.1 - 0.32 11.2 17.7 6.7 7.0 1.1 4.4 3 2 1 4 4 4 0 Uncharacterized protein conserved in bacteria (DUF2316) DUF812 PF05667.11 AIN96687.1 - 0.99 8.2 31.5 1.2 8.0 31.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF812) DUF99 PF01949.16 AIN96687.1 - 1.9 7.9 8.9 6 6.2 0.4 3.1 1 1 1 3 3 3 0 Protein of unknown function DUF99 MetOD2 PF18548.1 AIN96687.1 - 6 7.0 23.5 0.63 10.2 2.8 4.7 3 1 2 5 5 5 0 Metanogen output domain 2 Enkurin PF13864.6 AIN96687.1 - 8.6 6.9 29.4 5.3 7.6 5.7 4.0 1 1 3 4 4 4 0 Calmodulin-binding DUF148 PF02520.17 AIN96687.1 - 8.6 6.5 14.1 4.6 7.4 3.5 2.5 1 1 1 2 2 2 0 Domain of unknown function DUF148 CSD PF00313.22 AIN96689.1 - 7.7e-11 41.7 0.3 6.5e-06 25.9 0.1 3.9 4 0 0 4 4 4 2 'Cold-shock' DNA-binding domain Tub PF01167.18 AIN96690.1 - 1.7e-31 109.8 0.0 8.1e-30 104.3 0.0 2.5 2 1 0 2 2 2 2 Tub family Enolase_C PF00113.22 AIN96692.1 - 2.4e-129 430.8 0.0 3.3e-129 430.4 0.0 1.1 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.16 AIN96692.1 - 2.8e-56 189.3 0.1 5.1e-56 188.4 0.1 1.5 1 0 0 1 1 1 1 Enolase, N-terminal domain MR_MLE_C PF13378.6 AIN96692.1 - 5.1e-08 32.7 0.0 8.4e-08 32.0 0.0 1.4 1 1 0 1 1 1 1 Enolase C-terminal domain-like MAAL_C PF07476.11 AIN96692.1 - 0.00017 20.8 0.1 0.00034 19.9 0.1 1.4 1 0 0 1 1 1 1 Methylaspartate ammonia-lyase C-terminus FYVE PF01363.21 AIN96693.1 - 1.4e-16 60.3 20.2 3.5e-16 59.1 13.7 3.1 2 1 0 2 2 2 1 FYVE zinc finger Ras PF00071.22 AIN96693.1 - 2.5e-10 40.2 0.0 4.1e-10 39.5 0.0 1.3 1 0 0 1 1 1 1 Ras family Roc PF08477.13 AIN96693.1 - 8.8e-08 32.4 0.0 1.6e-07 31.6 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase F-box-like PF12937.7 AIN96693.1 - 0.00063 19.6 0.5 0.0017 18.2 0.1 2.0 2 0 0 2 2 2 1 F-box-like IBR PF01485.21 AIN96693.1 - 0.02 15.1 6.3 0.02 15.1 6.3 2.1 2 0 0 2 2 2 0 IBR domain, a half RING-finger domain Zf_RING PF16744.5 AIN96693.1 - 0.026 14.6 5.7 0.076 13.1 1.8 2.6 2 0 0 2 2 2 0 KIAA1045 RING finger AAA_7 PF12775.7 AIN96693.1 - 0.11 12.0 0.0 0.48 9.9 0.0 2.0 3 0 0 3 3 3 0 P-loop containing dynein motor region PAP_central PF04928.17 AIN96694.1 - 7.1e-55 185.7 0.0 1.2e-54 184.9 0.0 1.2 1 0 0 1 1 1 1 Poly(A) polymerase central domain PAP_RNA-bind PF04926.15 AIN96694.1 - 1.2e-34 119.4 0.0 3.3e-34 118.0 0.0 1.7 1 1 1 2 2 2 1 Poly(A) polymerase predicted RNA binding domain NTP_transf_2 PF01909.23 AIN96694.1 - 1.2e-05 25.5 0.0 2.7e-05 24.4 0.0 1.5 1 0 0 1 1 1 1 Nucleotidyltransferase domain DNA_pol_B_palm PF14792.6 AIN96694.1 - 0.025 14.8 0.0 0.061 13.5 0.0 1.6 1 0 0 1 1 1 0 DNA polymerase beta palm Carb_kinase PF01256.17 AIN96695.1 - 3.1e-50 170.9 5.0 5.5e-50 170.1 5.0 1.4 1 0 0 1 1 1 1 Carbohydrate kinase YjeF_N PF03853.15 AIN96695.1 - 1.6e-44 151.8 0.0 3.8e-44 150.6 0.0 1.7 1 0 0 1 1 1 1 YjeF-related protein N-terminus DFP PF04127.15 AIN96695.1 - 0.12 12.2 0.1 0.35 10.7 0.0 1.8 2 0 0 2 2 2 0 DNA / pantothenate metabolism flavoprotein PSS PF03034.15 AIN96696.1 - 4e-98 328.5 13.1 5.9e-98 328.0 13.1 1.3 1 0 0 1 1 1 1 Phosphatidyl serine synthase DUF4381 PF14316.6 AIN96696.1 - 0.046 14.0 10.1 1.5 9.1 0.3 3.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4381) DUF4131 PF13567.6 AIN96696.1 - 4.3 7.0 17.1 1.8 8.2 3.0 3.1 3 1 0 3 3 3 0 Domain of unknown function (DUF4131) NIF PF03031.18 AIN96697.1 - 4e-14 52.7 0.0 1.2e-06 28.4 0.0 2.1 2 0 0 2 2 2 2 NLI interacting factor-like phosphatase DUF4795 PF16043.5 AIN96698.1 - 0.0026 17.4 36.5 0.0053 16.4 2.0 6.7 4 2 1 6 6 6 2 Domain of unknown function (DUF4795) Spc7 PF08317.11 AIN96698.1 - 0.031 13.1 33.3 0.24 10.3 0.2 4.6 2 1 3 5 5 5 0 Spc7 kinetochore protein PspB PF06667.12 AIN96698.1 - 0.2 11.7 1.0 12 6.1 0.2 3.4 2 0 0 2 2 2 0 Phage shock protein B BLOC1_2 PF10046.9 AIN96698.1 - 0.27 11.6 25.7 0.25 11.7 2.2 4.9 6 0 0 6 6 6 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Lge1 PF11488.8 AIN96698.1 - 0.36 11.0 2.3 18 5.6 0.1 3.3 2 0 0 2 2 2 0 Transcriptional regulatory protein LGE1 HTH_37 PF13744.6 AIN96698.1 - 0.56 10.2 4.4 0.41 10.6 0.1 2.9 2 0 0 2 2 2 0 Helix-turn-helix domain NBP1 PF08537.10 AIN96698.1 - 1.6 8.1 8.4 0.55 9.6 1.1 2.7 2 0 0 2 2 2 0 Fungal Nap binding protein NBP1 Occludin_ELL PF07303.13 AIN96698.1 - 3.7 8.3 15.3 29 5.5 0.2 5.8 5 2 2 7 7 7 0 Occludin homology domain COG2 PF06148.11 AIN96698.1 - 5.4 7.1 20.7 0.17 12.0 0.7 5.1 4 1 1 5 5 5 0 COG (conserved oligomeric Golgi) complex component, COG2 SesA PF17107.5 AIN96698.1 - 7.5 6.8 8.9 8.6 6.6 1.0 4.1 2 1 1 3 3 3 0 N-terminal domain on NACHT_NTPase and P-loop NTPases HTH_37 PF13744.6 AIN96700.1 - 0.11 12.4 0.1 0.23 11.4 0.1 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain NRD1_2 PF01995.16 AIN96700.1 - 0.24 10.6 0.0 0.43 9.8 0.0 1.3 1 0 0 1 1 1 0 NrpR regulatory domains NRD1 and 2 Pax7 PF12360.8 AIN96701.1 - 0.048 13.9 0.2 0.11 12.7 0.2 1.6 1 0 0 1 1 1 0 Paired box protein 7 Ribosomal_S27 PF01599.19 AIN96703.1 - 1e-22 80.0 4.2 1.9e-22 79.2 4.2 1.5 1 0 0 1 1 1 1 Ribosomal protein S27a ubiquitin PF00240.23 AIN96703.1 - 1.2e-09 37.8 0.3 1.2e-08 34.6 0.0 2.4 2 1 0 2 2 2 1 Ubiquitin family Rad60-SLD PF11976.8 AIN96703.1 - 4.2e-05 23.3 0.3 0.00055 19.7 0.0 2.4 2 1 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like IBR PF01485.21 AIN96703.1 - 0.0069 16.6 0.7 0.011 15.9 0.7 1.4 1 0 0 1 1 1 1 IBR domain, a half RING-finger domain F420_oxidored PF03807.17 AIN96704.1 - 1.4e-06 28.8 0.0 4.2e-06 27.3 0.0 1.9 1 1 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent PDH PF02153.17 AIN96704.1 - 0.069 12.1 0.0 0.11 11.5 0.0 1.3 1 0 0 1 1 1 0 Prephenate dehydrogenase TSNAXIP1_N PF15739.5 AIN96705.1 - 0.028 14.8 0.8 0.028 14.8 0.8 3.4 4 0 0 4 4 4 0 Translin-associated factor X-interacting N-terminus DUF919 PF06034.11 AIN96705.1 - 6.7 6.6 6.2 11 5.9 0.0 3.3 3 0 0 3 3 3 0 Nucleopolyhedrovirus protein of unknown function (DUF919) Pkinase PF00069.25 AIN96706.1 - 8.1e-64 215.5 0.0 4.3e-56 190.2 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 AIN96706.1 - 1.4e-35 122.8 0.0 4e-33 114.8 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 AIN96706.1 - 0.00011 21.2 0.0 0.00011 21.2 0.0 2.2 2 0 0 2 2 2 1 Fungal protein kinase APH PF01636.23 AIN96706.1 - 0.026 14.4 0.0 0.05 13.5 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.14 AIN96706.1 - 0.094 12.1 0.0 0.17 11.2 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 AIN96706.1 - 0.17 11.1 0.0 0.29 10.4 0.0 1.3 1 0 0 1 1 1 0 Kinase-like SHMT PF00464.19 AIN96708.1 - 6.4e-174 578.2 0.0 7.5e-174 578.0 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase DnaJ PF00226.31 AIN96709.1 - 4.9e-20 71.4 3.0 1.2e-19 70.2 3.0 1.7 1 0 0 1 1 1 1 DnaJ domain TPR_19 PF14559.6 AIN96709.1 - 1.1e-14 54.6 18.7 0.0007 20.0 0.3 6.4 4 2 2 6 6 6 5 Tetratricopeptide repeat TPR_16 PF13432.6 AIN96709.1 - 0.00011 22.8 15.1 0.031 14.9 0.3 5.0 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_14 PF13428.6 AIN96709.1 - 0.00031 21.3 23.7 1.1 10.2 0.0 7.8 5 3 5 10 10 9 2 Tetratricopeptide repeat TPR_8 PF13181.6 AIN96709.1 - 0.00043 20.3 2.5 0.33 11.3 0.0 4.7 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_9 PF13371.6 AIN96709.1 - 0.00069 19.7 13.8 0.2 11.8 0.8 4.8 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_12 PF13424.6 AIN96709.1 - 0.004 17.4 10.9 0.57 10.5 1.3 4.6 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_6 PF13174.6 AIN96709.1 - 0.026 15.2 11.7 1.7e+02 3.2 0.0 7.8 9 0 0 9 9 8 0 Tetratricopeptide repeat TPR_11 PF13414.6 AIN96709.1 - 0.036 13.7 0.0 11 5.8 0.0 2.7 2 0 0 2 2 2 0 TPR repeat TPR_2 PF07719.17 AIN96709.1 - 0.04 14.0 12.7 13 6.2 0.0 6.9 8 0 0 8 8 7 0 Tetratricopeptide repeat TPR_1 PF00515.28 AIN96709.1 - 0.076 12.9 6.3 22 5.1 0.0 5.1 6 0 0 6 6 6 0 Tetratricopeptide repeat DUF884 PF05959.11 AIN96709.1 - 0.11 12.1 0.1 0.2 11.3 0.1 1.4 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF884) Mhr1 PF12829.7 AIN96709.1 - 0.16 12.1 0.7 6.8 6.9 0.1 2.9 3 0 0 3 3 3 0 Transcriptional regulation of mitochondrial recombination TPR_17 PF13431.6 AIN96709.1 - 0.17 12.3 1.5 14 6.3 0.0 4.5 5 0 0 5 5 5 0 Tetratricopeptide repeat DUF4726 PF15855.5 AIN96709.1 - 0.18 12.0 0.9 6.7 7.0 0.1 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4726) Alkyl_sulf_dimr PF14863.6 AIN96709.1 - 0.2 12.1 1.8 4.1 7.9 0.1 3.2 3 0 0 3 3 3 0 Alkyl sulfatase dimerisation HemY_N PF07219.13 AIN96709.1 - 0.51 10.5 3.6 3.7 7.8 0.1 3.4 3 0 0 3 3 3 0 HemY protein N-terminus DUF5321 PF17254.2 AIN96709.1 - 0.94 8.9 4.9 1.8 8.0 4.9 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5321) TPR_7 PF13176.6 AIN96709.1 - 1.2 9.3 5.1 9.1 6.6 0.0 4.4 5 0 0 5 5 5 0 Tetratricopeptide repeat FA_desaturase PF00487.24 AIN96710.1 - 2.7e-34 119.2 11.7 2.7e-34 119.2 11.7 1.7 1 1 1 2 2 2 1 Fatty acid desaturase Cyt-b5 PF00173.28 AIN96710.1 - 0.0014 18.7 0.0 0.003 17.7 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain MMR_HSR1 PF01926.23 AIN96711.1 - 0.028 14.5 0.0 0.34 11.0 0.0 2.2 1 1 0 1 1 1 0 50S ribosome-binding GTPase DLIC PF05783.11 AIN96711.1 - 0.2 10.4 0.0 0.71 8.6 0.0 1.9 3 0 0 3 3 3 0 Dynein light intermediate chain (DLIC) NAD_binding_5 PF07994.12 AIN96712.1 - 1.8e-134 448.2 0.0 2.1e-134 448.0 0.0 1.0 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase Inos-1-P_synth PF01658.17 AIN96712.1 - 3.3e-44 149.6 0.0 5.7e-44 148.8 0.0 1.4 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase tRNA-synt_1b PF00579.25 AIN96713.1 - 3e-53 181.0 0.0 1.1e-48 166.0 0.0 2.5 2 1 0 2 2 2 2 tRNA synthetases class I (W and Y) EMP24_GP25L PF01105.24 AIN96715.1 - 1e-20 74.4 0.0 1.3e-20 74.1 0.0 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD DUF2309 PF10070.9 AIN96716.1 - 0.059 11.7 0.1 0.069 11.5 0.1 1.0 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2309) Pkinase PF00069.25 AIN96717.1 - 1.6e-64 217.8 0.0 2e-64 217.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 AIN96717.1 - 4.9e-44 150.6 0.0 7.2e-44 150.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 AIN96717.1 - 1.1e-06 28.1 0.1 2.4e-05 23.8 0.0 2.2 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 AIN96717.1 - 0.00017 20.5 0.0 0.00031 19.6 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase WD40 PF00400.32 AIN96719.1 - 0.0005 20.8 19.9 19 6.3 0.0 8.9 10 0 0 10 10 10 4 WD domain, G-beta repeat IFT46_B_C PF12317.8 AIN96719.1 - 0.076 12.7 1.9 0.18 11.5 0.0 2.4 3 0 0 3 3 3 0 Intraflagellar transport complex B protein 46 C terminal FlaC_arch PF05377.11 AIN96719.1 - 4.9 7.6 6.2 24 5.4 0.6 3.7 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) C2 PF00168.30 AIN96720.1 - 9.4e-07 29.1 0.0 0.07 13.4 0.0 2.5 2 0 0 2 2 2 2 C2 domain Rubredoxin PF00301.20 AIN96720.1 - 0.081 13.0 0.2 0.21 11.7 0.2 1.7 1 0 0 1 1 1 0 Rubredoxin Vac14_Fig4_bd PF11916.8 AIN96721.1 - 4.9e-46 156.6 6.0 5.8e-46 156.4 4.9 1.7 2 0 0 2 2 2 1 Vacuolar protein 14 C-terminal Fig4p binding Vac14_Fab1_bd PF12755.7 AIN96721.1 - 3.4e-09 37.2 0.2 1.8e-07 31.6 0.0 3.0 3 0 0 3 3 3 1 Vacuolar 14 Fab1-binding region HEAT PF02985.22 AIN96721.1 - 0.013 15.7 0.0 0.013 15.7 0.0 4.5 4 0 0 4 4 4 0 HEAT repeat Cnd1 PF12717.7 AIN96721.1 - 0.028 14.5 0.0 0.19 11.8 0.0 2.3 2 0 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 AIN96721.1 - 4 7.9 8.5 6 7.3 0.0 4.6 5 0 0 5 5 5 0 HEAT repeats MPC PF03650.13 AIN96722.1 - 6.7e-15 55.2 0.1 8.2e-15 54.9 0.1 1.1 1 0 0 1 1 1 1 Mitochondrial pyruvate carriers TINF2_N PF14973.6 AIN96723.1 - 0.067 13.5 0.3 0.17 12.2 0.3 1.6 1 0 0 1 1 1 0 TERF1-interacting nuclear factor 2 N-terminus AUDH_Cupin PF18637.1 AIN96723.1 - 0.14 12.2 1.2 1.1 9.3 0.1 2.7 2 1 1 3 3 3 0 Aldos-2-ulose dehydratase/isomerase (AUDH) Cupin domain GST_N_3 PF13417.6 AIN96724.1 - 1e-07 32.2 0.0 1.9e-07 31.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Glutaredoxin PF00462.24 AIN96724.1 - 1.8e-07 31.3 0.8 4.3e-07 30.0 0.4 1.9 2 0 0 2 2 2 1 Glutaredoxin GST_N_2 PF13409.6 AIN96724.1 - 0.1 12.9 0.0 0.2 12.0 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain Syja_N PF02383.18 AIN96725.1 - 1e-26 94.0 0.0 1.5e-26 93.5 0.0 1.2 1 0 0 1 1 1 1 SacI homology domain CENP-T_C PF15511.6 AIN96726.1 - 1e-05 25.6 0.1 1.7e-05 24.9 0.0 1.3 1 1 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold TAF PF02969.17 AIN96726.1 - 0.00056 20.0 0.1 0.00088 19.4 0.1 1.3 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.23 AIN96726.1 - 0.00058 20.1 0.4 0.00081 19.6 0.0 1.4 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.13 AIN96726.1 - 0.0025 17.8 0.0 0.0029 17.6 0.0 1.2 1 0 0 1 1 1 1 Bromodomain associated Histone PF00125.24 AIN96726.1 - 0.0042 17.4 1.7 0.0082 16.5 1.7 1.5 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID-31kDa PF02291.15 AIN96726.1 - 0.063 13.3 0.0 0.083 13.0 0.0 1.2 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit GDA1_CD39 PF01150.17 AIN96728.1 - 1.1e-82 278.0 0.0 1.4e-82 277.6 0.0 1.1 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family Ppx-GppA PF02541.16 AIN96728.1 - 0.00014 21.4 0.0 0.00021 20.9 0.0 1.2 1 0 0 1 1 1 1 Ppx/GppA phosphatase family Lysine_decarbox PF03641.14 AIN96729.1 - 4.2e-23 81.9 0.0 8.2e-23 80.9 0.0 1.5 1 0 0 1 1 1 1 Possible lysine decarboxylase LDcluster4 PF18306.1 AIN96729.1 - 3.6e-08 33.1 0.0 7.6e-08 32.1 0.0 1.5 1 1 0 1 1 1 1 SLOG cluster4 family NAD_binding_1 PF00175.21 AIN96730.1 - 3.6e-28 98.4 0.0 5.9e-28 97.7 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 AIN96730.1 - 4.3e-25 87.9 0.0 6.6e-25 87.4 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.12 AIN96730.1 - 3.3e-06 27.3 0.0 0.00025 21.2 0.0 2.2 2 0 0 2 2 2 2 Ferric reductase NAD binding domain MIF4G PF02854.19 AIN96731.1 - 5.4e-25 88.3 0.8 8.9e-25 87.6 0.8 1.4 1 0 0 1 1 1 1 MIF4G domain CRM1_C PF08767.11 AIN96731.1 - 0.00019 20.8 0.0 0.00053 19.3 0.0 1.7 1 0 0 1 1 1 1 CRM1 C terminal IMS PF00817.20 AIN96731.1 - 0.18 11.8 0.0 3.9 7.5 0.0 2.5 3 0 0 3 3 3 0 impB/mucB/samB family CDT1_C PF16679.5 AIN96732.1 - 0.47 10.9 2.9 3.5 8.1 0.0 3.0 3 1 0 3 3 3 0 DNA replication factor Cdt1 C-terminal domain AAA_2 PF07724.14 AIN96734.1 - 1.1e-39 136.2 2.0 3.8e-31 108.5 0.8 2.8 1 1 1 2 2 2 2 AAA domain (Cdc48 subfamily) AAA PF00004.29 AIN96734.1 - 1.1e-13 51.7 0.1 5.9e-06 26.7 0.0 3.0 2 1 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 AIN96734.1 - 6.9e-09 35.8 0.4 1.9e-05 24.7 0.0 2.5 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 AIN96734.1 - 6e-06 26.6 0.0 0.00028 21.2 0.0 2.4 2 0 0 2 2 2 1 AAA domain MCM PF00493.23 AIN96734.1 - 1.5e-05 24.2 0.1 0.0019 17.3 0.0 2.4 2 0 0 2 2 2 1 MCM P-loop domain TniB PF05621.11 AIN96734.1 - 3.9e-05 23.1 0.2 0.0034 16.8 0.0 2.3 2 0 0 2 2 2 1 Bacterial TniB protein AAA_18 PF13238.6 AIN96734.1 - 7.9e-05 23.2 0.2 0.00026 21.5 0.0 1.9 2 0 0 2 2 1 1 AAA domain Mg_chelatase PF01078.21 AIN96734.1 - 8.6e-05 22.0 0.1 0.002 17.5 0.0 2.8 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI ClpB_D2-small PF10431.9 AIN96734.1 - 9.8e-05 22.3 0.7 0.00034 20.6 0.0 2.3 2 0 0 2 2 2 1 C-terminal, D2-small domain, of ClpB protein AAA_16 PF13191.6 AIN96734.1 - 0.0002 21.8 0.3 0.00055 20.4 0.3 1.8 1 1 0 1 1 1 1 AAA ATPase domain TIP49 PF06068.13 AIN96734.1 - 0.00079 18.7 1.2 0.0011 18.3 0.0 1.8 2 1 0 2 2 2 1 TIP49 P-loop domain NTPase_1 PF03266.15 AIN96734.1 - 0.0008 19.4 1.0 0.51 10.2 0.0 2.6 2 0 0 2 2 2 2 NTPase RuvB_N PF05496.12 AIN96734.1 - 0.0015 18.3 0.1 0.013 15.3 0.0 2.3 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain DEAD PF00270.29 AIN96734.1 - 0.0015 18.3 0.1 1.1 9.0 0.0 2.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_14 PF13173.6 AIN96734.1 - 0.0053 16.8 0.1 2.9 7.9 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_24 PF13479.6 AIN96734.1 - 0.0067 16.2 0.7 0.33 10.6 0.1 2.6 2 1 0 2 2 2 1 AAA domain AAA_33 PF13671.6 AIN96734.1 - 0.008 16.3 0.0 0.025 14.7 0.0 1.9 2 0 0 2 2 1 1 AAA domain TsaE PF02367.17 AIN96734.1 - 0.012 15.6 0.0 0.035 14.1 0.0 1.8 2 0 0 2 2 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_28 PF13521.6 AIN96734.1 - 0.017 15.4 0.1 0.13 12.5 0.0 2.4 2 1 1 3 3 3 0 AAA domain Sigma54_activat PF00158.26 AIN96734.1 - 0.018 14.8 0.0 0.058 13.1 0.0 1.8 2 0 0 2 2 1 0 Sigma-54 interaction domain Zeta_toxin PF06414.12 AIN96734.1 - 0.023 14.0 0.0 0.053 12.8 0.0 1.7 1 0 0 1 1 1 0 Zeta toxin CPT PF07931.12 AIN96734.1 - 0.029 14.2 0.3 0.24 11.2 0.0 2.5 3 0 0 3 3 3 0 Chloramphenicol phosphotransferase-like protein ABC_tran PF00005.27 AIN96734.1 - 0.036 14.6 0.1 0.084 13.4 0.1 1.6 1 0 0 1 1 1 0 ABC transporter IstB_IS21 PF01695.17 AIN96734.1 - 0.041 13.6 0.0 0.12 12.1 0.0 1.7 1 0 0 1 1 1 0 IstB-like ATP binding protein RsgA_GTPase PF03193.16 AIN96734.1 - 0.042 13.8 0.0 0.091 12.7 0.0 1.6 1 0 0 1 1 1 0 RsgA GTPase AAA_19 PF13245.6 AIN96734.1 - 0.043 14.2 1.4 0.095 13.0 0.8 1.9 2 1 0 2 2 1 0 AAA domain AAA_7 PF12775.7 AIN96734.1 - 0.043 13.3 0.0 0.074 12.6 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region NACHT PF05729.12 AIN96734.1 - 0.043 13.7 0.1 3 7.8 0.0 2.7 2 1 0 2 2 2 0 NACHT domain RNA_helicase PF00910.22 AIN96734.1 - 0.13 12.7 0.0 0.86 10.0 0.0 2.3 2 1 0 2 2 2 0 RNA helicase AAA_17 PF13207.6 AIN96734.1 - 2 8.8 6.1 4.1 7.8 0.3 3.8 3 1 1 4 4 4 0 AAA domain FMO-like PF00743.19 AIN96735.1 - 6.7e-27 94.1 0.1 1.7e-22 79.6 0.1 2.1 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 AIN96735.1 - 8.2e-14 51.5 0.0 3.9e-13 49.3 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 AIN96735.1 - 2.4e-09 36.9 0.4 9.2e-06 25.1 0.1 3.2 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 AIN96735.1 - 7.8e-08 31.8 0.9 3.4e-06 26.5 0.4 2.2 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 AIN96735.1 - 3.4e-06 27.2 0.0 1.7e-05 25.0 0.0 2.4 2 1 0 2 2 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 AIN96735.1 - 0.00046 20.7 0.1 0.59 10.7 0.0 3.1 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 AIN96735.1 - 0.011 14.5 0.1 0.016 13.9 0.1 1.2 1 0 0 1 1 1 0 HI0933-like protein IlvN PF07991.12 AIN96735.1 - 0.019 14.6 0.0 3.4 7.2 0.0 2.6 3 0 0 3 3 3 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain NAD_binding_9 PF13454.6 AIN96735.1 - 0.022 14.8 0.3 0.35 10.8 0.3 2.8 1 1 0 1 1 1 0 FAD-NAD(P)-binding AlaDh_PNT_C PF01262.21 AIN96735.1 - 0.029 13.6 0.1 7.3 5.8 0.0 2.3 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_3 PF01494.19 AIN96735.1 - 0.044 13.0 0.1 0.098 11.9 0.1 1.5 1 0 0 1 1 1 0 FAD binding domain NAD_binding_7 PF13241.6 AIN96735.1 - 0.086 13.3 0.2 3.9 8.0 0.0 3.0 3 0 0 3 3 3 0 Putative NAD(P)-binding GIDA PF01134.22 AIN96735.1 - 0.086 11.9 0.8 1.7 7.6 0.0 2.1 2 0 0 2 2 2 0 Glucose inhibited division protein A Mito_carr PF00153.27 AIN96737.1 - 2.1e-44 149.3 0.6 7.7e-16 57.8 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein CbiM PF01891.16 AIN96737.1 - 0.0029 17.5 2.4 0.037 13.8 0.0 2.4 2 1 1 3 3 3 2 Cobalt uptake substrate-specific transmembrane region DEAD PF00270.29 AIN96738.1 - 1.2e-41 142.4 0.1 2.4e-41 141.4 0.1 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 AIN96738.1 - 1.8e-25 89.4 0.1 1.8e-25 89.4 0.1 3.4 3 1 1 4 4 4 1 Helicase conserved C-terminal domain zf-CCCH PF00642.24 AIN96739.1 - 2.3e-07 30.5 5.3 2.3e-07 30.5 5.3 2.3 2 0 0 2 2 2 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) oligo_HPY PF08352.12 AIN96739.1 - 0.011 16.2 3.7 0.68 10.5 0.6 2.6 2 0 0 2 2 2 0 Oligopeptide/dipeptide transporter, C-terminal region Torus PF16131.5 AIN96739.1 - 0.02 15.6 5.2 2 9.1 0.6 2.2 2 0 0 2 2 2 0 Torus domain zf-CCCH_4 PF18044.1 AIN96739.1 - 2.7 7.9 11.1 0.13 12.0 4.2 2.4 2 0 0 2 2 2 0 CCCH-type zinc finger zf-CCCH PF00642.24 AIN96740.1 - 4.8e-07 29.5 4.0 8e-07 28.8 4.0 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 AIN96740.1 - 5.2e-05 22.9 2.3 8.7e-05 22.2 2.3 1.4 1 0 0 1 1 1 1 CCCH-type zinc finger zf_CCCH_4 PF18345.1 AIN96740.1 - 0.032 14.3 2.6 0.058 13.5 2.6 1.5 1 0 0 1 1 1 0 Zinc finger domain zf-CCCH_2 PF14608.6 AIN96740.1 - 0.062 13.8 2.2 0.12 12.9 2.2 1.5 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger PP2C PF00481.21 AIN96741.1 - 1.3e-66 224.8 0.4 1.3e-66 224.8 0.4 1.6 2 0 0 2 2 2 1 Protein phosphatase 2C PP2C_2 PF13672.6 AIN96741.1 - 3.9e-05 23.4 0.9 0.00092 18.9 0.1 2.5 2 1 0 2 2 2 1 Protein phosphatase 2C DUF3276 PF11680.8 AIN96741.1 - 0.0038 17.4 3.3 0.0071 16.5 2.2 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF3276) Gastrin PF00918.17 AIN96741.1 - 0.027 15.4 0.6 0.068 14.1 0.6 1.6 1 0 0 1 1 1 0 Gastrin/cholecystokinin family LPD13 PF18825.1 AIN96741.1 - 0.21 11.3 2.8 0.55 10.0 2.8 1.7 2 0 0 2 2 2 0 Large polyvalent protein-associated domain 13 Pkinase PF00069.25 AIN96742.1 - 6.2e-43 147.1 0.0 1e-42 146.3 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 AIN96742.1 - 7.2e-15 55.0 0.0 1.2e-14 54.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 AIN96742.1 - 2.2e-05 24.5 0.3 0.0024 17.8 0.0 2.6 2 1 0 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 AIN96742.1 - 0.0055 16.3 0.0 0.011 15.4 0.0 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase ATG16 PF08614.11 AIN96743.1 - 0.018 15.3 0.3 0.018 15.3 0.3 3.4 4 0 0 4 4 4 0 Autophagy protein 16 (ATG16) CASP_C PF08172.12 AIN96743.1 - 0.048 13.0 0.5 0.99 8.7 0.0 2.3 2 0 0 2 2 2 0 CASP C terminal TolA_bind_tri PF16331.5 AIN96743.1 - 0.074 13.1 1.4 15 5.7 0.0 3.4 3 0 0 3 3 3 0 TolA binding protein trimerisation Fib_alpha PF08702.10 AIN96743.1 - 0.08 13.1 0.8 2.1 8.5 0.1 2.5 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family Sec8_exocyst PF04048.14 AIN96743.1 - 0.19 11.6 1.1 13 5.7 0.2 2.5 2 0 0 2 2 2 0 Sec8 exocyst complex component specific domain HIP1_clath_bdg PF16515.5 AIN96743.1 - 0.7 10.5 7.7 28 5.4 0.2 3.5 3 0 0 3 3 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 FliJ PF02050.16 AIN96743.1 - 1.4 9.2 6.0 12 6.1 0.4 2.7 3 0 0 3 3 3 0 Flagellar FliJ protein SlyX PF04102.12 AIN96743.1 - 1.4 9.6 5.5 4 8.1 0.0 3.5 4 0 0 4 4 4 0 SlyX Cyt-b5 PF00173.28 AIN96744.1 - 3.6e-07 30.2 0.0 5.5e-07 29.6 0.0 1.3 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Ribosomal_L13 PF00572.18 AIN96746.1 - 2.2e-06 27.9 3.8 2.8e-05 24.4 0.9 2.6 2 1 0 2 2 2 1 Ribosomal protein L13 DUF4455 PF14643.6 AIN96746.1 - 0.011 14.4 1.3 0.016 13.9 1.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4455) CAP160 PF07918.11 AIN96747.1 - 1.7 8.4 4.4 4.6 7.1 4.4 1.7 1 0 0 1 1 1 0 CAP160 repeat Metallophos PF00149.28 AIN96748.1 - 4.4e-32 112.2 0.0 5.7e-32 111.9 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 AIN96748.1 - 0.01 16.3 0.8 0.034 14.6 0.3 2.1 2 0 0 2 2 2 0 Serine-threonine protein phosphatase N-terminal domain WD40 PF00400.32 AIN96750.1 - 4.4e-10 40.0 1.0 0.0032 18.2 0.0 4.4 4 0 0 4 4 4 3 WD domain, G-beta repeat tRNA-synt_2 PF00152.20 AIN96751.1 - 4.1e-76 256.1 0.1 6.4e-76 255.4 0.0 1.4 2 0 0 2 2 2 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 AIN96751.1 - 9e-12 44.8 0.1 1.8e-11 43.9 0.1 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 AIN96751.1 - 5.9e-07 29.2 0.0 0.0056 16.2 0.0 2.9 3 0 0 3 3 3 2 tRNA synthetases class II core domain (F) YabA PF06156.13 AIN96751.1 - 0.085 13.5 0.7 0.16 12.6 0.1 1.7 2 0 0 2 2 2 0 Initiation control protein YabA DUF4580 PF15162.6 AIN96751.1 - 0.19 11.3 0.1 0.39 10.3 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4580) Cellulose_synt PF03552.14 AIN96754.1 - 0.048 12.2 0.4 0.065 11.7 0.4 1.1 1 0 0 1 1 1 0 Cellulose synthase DUF1002 PF06207.11 AIN96754.1 - 0.066 12.7 0.0 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1002) RPA_C PF08784.11 AIN96755.1 - 7.2e-12 45.9 1.1 7.2e-12 45.9 1.1 2.2 3 0 0 3 3 3 1 Replication protein A C terminal tRNA_anti-codon PF01336.25 AIN96755.1 - 2.5e-08 33.8 0.1 4.6e-08 32.9 0.1 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain PPR_2 PF13041.6 AIN96756.1 - 5.6e-07 29.6 1.1 0.029 14.6 0.0 2.3 2 0 0 2 2 2 2 PPR repeat family PPR_long PF17177.4 AIN96756.1 - 0.0013 18.1 0.0 0.24 10.7 0.0 2.1 1 1 1 2 2 2 2 Pentacotripeptide-repeat region of PRORP RPM2 PF08579.11 AIN96756.1 - 0.0087 16.5 0.0 0.014 15.8 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial ribonuclease P subunit (RPM2) FERM_f0 PF16511.5 AIN96756.1 - 0.017 15.4 0.0 0.053 13.8 0.0 1.7 2 0 0 2 2 2 0 N-terminal or F0 domain of Talin-head FERM PPR_3 PF13812.6 AIN96756.1 - 0.02 15.0 0.1 0.6 10.2 0.0 2.2 2 0 0 2 2 2 0 Pentatricopeptide repeat domain Ecotin PF03974.13 AIN96758.1 - 1.6e-38 131.4 0.0 1.9e-38 131.2 0.0 1.0 1 0 0 1 1 1 1 Ecotin Abhydrolase_3 PF07859.13 AIN96760.1 - 2.9e-12 46.9 0.2 6.5e-12 45.8 0.1 1.6 2 0 0 2 2 2 1 alpha/beta hydrolase fold COesterase PF00135.28 AIN96760.1 - 1.4e-09 37.3 0.2 2.3e-08 33.4 0.0 2.2 2 0 0 2 2 2 1 Carboxylesterase family Abhydrolase_6 PF12697.7 AIN96760.1 - 3.2e-06 27.9 0.0 7.6e-06 26.7 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 AIN96760.1 - 3.5e-05 23.4 0.7 0.036 13.5 0.1 3.3 3 1 0 3 3 3 2 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 AIN96760.1 - 0.012 15.3 0.1 0.028 14.1 0.1 1.6 1 0 0 1 1 1 0 alpha/beta hydrolase fold DUF4566 PF15130.6 AIN96760.1 - 0.055 12.9 0.0 0.15 11.5 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4566) Abhydrolase_3 PF07859.13 AIN96761.1 - 4e-11 43.2 0.1 7.4e-11 42.3 0.1 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 AIN96761.1 - 2.8e-09 36.4 0.0 4.9e-09 35.6 0.0 1.3 1 0 0 1 1 1 1 Carboxylesterase family Peptidase_S9 PF00326.21 AIN96761.1 - 1.3e-05 24.8 0.1 0.018 14.5 0.1 2.7 2 1 0 2 2 2 2 Prolyl oligopeptidase family Chlorophyllase2 PF12740.7 AIN96761.1 - 0.0004 19.4 0.0 0.00069 18.6 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase enzyme Abhydrolase_1 PF00561.20 AIN96761.1 - 0.014 15.0 0.1 0.03 14.0 0.1 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 AIN96761.1 - 0.063 12.5 0.0 0.24 10.6 0.0 1.9 2 0 0 2 2 2 0 Serine aminopeptidase, S33 PseudoU_synth_2 PF00849.22 AIN96763.1 - 6.8e-17 62.0 3.8 2.1e-07 31.2 0.8 3.6 3 1 0 3 3 3 3 RNA pseudouridylate synthase Ribosomal_60s PF00428.19 AIN96764.1 - 9e-21 74.3 12.9 1.1e-20 74.0 12.9 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein Arg_repressor_C PF02863.18 AIN96764.1 - 0.0045 16.8 0.8 0.0045 16.8 0.8 1.7 2 0 0 2 2 2 1 Arginine repressor, C-terminal domain Asparaginase PF00710.20 AIN96765.1 - 6.2e-54 182.5 0.0 1.3e-53 181.4 0.0 1.5 2 0 0 2 2 2 1 Asparaginase, N-terminal Asparaginase_C PF17763.1 AIN96765.1 - 1.9e-20 73.2 0.1 2.9e-20 72.6 0.1 1.3 1 0 0 1 1 1 1 Glutaminase/Asparaginase C-terminal domain DUF3648 PF12364.8 AIN96766.1 - 0.013 15.7 0.5 0.054 13.7 0.4 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF3648) PPR_2 PF13041.6 AIN96767.1 - 0.045 14.0 0.0 0.92 9.7 0.0 2.5 1 1 1 2 2 2 0 PPR repeat family DUF3322 PF11795.8 AIN96767.1 - 2.3 8.2 10.2 7.2 6.6 0.5 3.6 4 1 0 4 4 4 0 Uncharacterized protein conserved in bacteria N-term (DUF3322) Peptidase_M50B PF13398.6 AIN96768.1 - 0.045 13.4 0.1 0.052 13.2 0.1 1.1 1 0 0 1 1 1 0 Peptidase M50B-like AAA PF00004.29 AIN96771.1 - 1.4e-38 132.3 0.0 2.4e-38 131.5 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 AIN96771.1 - 2e-11 43.5 0.1 4.6e-11 42.3 0.1 1.7 1 0 0 1 1 1 1 AAA+ lid domain Vps4_C PF09336.10 AIN96771.1 - 3e-08 33.5 0.0 9.1e-08 32.0 0.0 1.8 1 0 0 1 1 1 1 Vps4 C terminal oligomerisation domain AAA_5 PF07728.14 AIN96771.1 - 1.6e-05 24.9 0.1 0.00012 22.1 0.1 2.5 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 AIN96771.1 - 3.6e-05 23.6 0.0 8.1e-05 22.4 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 AIN96771.1 - 0.00023 21.6 2.7 0.022 15.2 0.0 3.6 2 1 1 3 3 3 1 AAA ATPase domain AAA_22 PF13401.6 AIN96771.1 - 0.00044 20.5 0.1 0.0088 16.3 0.1 2.7 1 1 1 2 2 2 1 AAA domain TIP49 PF06068.13 AIN96771.1 - 0.0034 16.6 0.0 0.0055 15.9 0.0 1.3 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_2 PF07724.14 AIN96771.1 - 0.0035 17.5 0.0 0.0061 16.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) Mg_chelatase PF01078.21 AIN96771.1 - 0.0047 16.3 0.1 0.013 14.9 0.1 1.7 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 AIN96771.1 - 0.0061 16.3 0.0 0.011 15.4 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_25 PF13481.6 AIN96771.1 - 0.013 15.0 0.2 0.59 9.7 0.0 2.6 1 1 1 2 2 2 0 AAA domain AAA_18 PF13238.6 AIN96771.1 - 0.024 15.2 0.0 0.052 14.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain DUF815 PF05673.13 AIN96771.1 - 0.039 13.1 0.0 0.08 12.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_33 PF13671.6 AIN96771.1 - 0.047 13.9 0.0 0.13 12.5 0.0 1.8 1 1 0 1 1 1 0 AAA domain AAA_14 PF13173.6 AIN96771.1 - 0.077 13.0 0.0 0.15 12.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 AIN96771.1 - 0.11 12.2 0.0 0.22 11.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain Parvo_NS1 PF01057.17 AIN96771.1 - 0.12 11.4 0.0 0.2 10.7 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 RNA_helicase PF00910.22 AIN96771.1 - 0.15 12.5 0.0 0.28 11.6 0.0 1.4 1 0 0 1 1 1 0 RNA helicase TniB PF05621.11 AIN96771.1 - 0.19 11.1 0.0 2.8 7.3 0.0 2.5 3 0 0 3 3 3 0 Bacterial TniB protein Ecotin PF03974.13 AIN96772.1 - 6.8e-42 142.3 0.0 8e-42 142.1 0.0 1.0 1 0 0 1 1 1 1 Ecotin Ecotin PF03974.13 AIN96773.1 - 1.1e-34 119.1 0.0 1.7e-34 118.4 0.0 1.3 1 0 0 1 1 1 1 Ecotin Fungal_TACC PF12709.7 AIN96775.1 - 0.1 13.1 0.1 0.1 13.1 0.1 6.3 7 1 2 9 9 9 0 Fungal Transforming acidic coiled-coil (TACC) proteins HDV_ag PF01517.18 AIN96775.1 - 0.82 9.4 5.9 0.43 10.4 1.8 2.7 2 0 0 2 2 2 0 Hepatitis delta virus delta antigen WXG100 PF06013.12 AIN96775.1 - 1.6 9.0 15.7 1.2 9.4 0.8 4.9 3 1 0 3 3 3 0 Proteins of 100 residues with WXG DUF3587 PF12132.8 AIN96776.1 - 0.16 11.4 0.4 0.28 10.6 0.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3587) RPT PF13446.6 AIN96777.1 - 0.0039 17.1 0.2 0.22 11.5 0.1 3.3 3 0 0 3 3 3 1 A repeated domain in UCH-protein ATG16 PF08614.11 AIN96777.1 - 0.0074 16.5 13.7 0.0074 16.5 13.7 3.7 3 1 0 4 4 4 1 Autophagy protein 16 (ATG16) DUF5094 PF17015.5 AIN96777.1 - 0.028 14.5 1.1 41 4.2 4.3 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF5094) TcdB_N PF12918.7 AIN96777.1 - 0.042 14.1 0.0 0.094 13.0 0.0 1.6 1 0 0 1 1 1 0 TcdB toxin N-terminal helical domain Mito_fiss_reg PF05308.11 AIN96777.1 - 0.073 13.2 5.7 0.17 11.9 5.7 1.7 1 0 0 1 1 1 0 Mitochondrial fission regulator Fez1 PF06818.15 AIN96777.1 - 0.085 13.3 19.5 0.55 10.7 8.0 3.9 3 1 0 3 3 3 0 Fez1 NBP1 PF08537.10 AIN96777.1 - 0.11 12.0 0.0 0.11 12.0 0.0 2.6 3 0 0 3 3 3 0 Fungal Nap binding protein NBP1 HMMR_N PF15905.5 AIN96777.1 - 0.46 9.9 15.5 0.06 12.8 6.1 2.5 2 0 0 2 2 2 0 Hyaluronan mediated motility receptor N-terminal ERM PF00769.19 AIN96777.1 - 0.63 9.8 20.2 1.2 8.8 1.1 2.8 2 0 0 2 2 2 0 Ezrin/radixin/moesin family Lebercilin PF15619.6 AIN96777.1 - 1 9.0 25.9 3.5 7.2 8.6 4.5 4 1 1 5 5 5 0 Ciliary protein causing Leber congenital amaurosis disease DUF1664 PF07889.12 AIN96777.1 - 1.5 8.9 9.2 0.68 10.0 1.8 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) V_ATPase_I PF01496.19 AIN96777.1 - 3.1 5.6 5.5 6.6 4.5 4.4 1.8 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family DUF4618 PF15397.6 AIN96777.1 - 3.3 7.1 12.1 0.35 10.2 4.5 2.9 2 1 0 3 3 3 0 Domain of unknown function (DUF4618) Fmp27_WPPW PF10359.9 AIN96777.1 - 5.7 5.7 11.3 0.22 10.3 5.5 1.5 2 0 0 2 2 2 0 RNA pol II promoter Fmp27 protein domain CC2-LZ PF16516.5 AIN96777.1 - 6.1 7.3 17.7 0.63 10.4 0.4 3.7 3 1 0 3 3 3 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator UPF0242 PF06785.11 AIN96777.1 - 9.6 6.3 16.4 12 5.9 5.3 3.4 3 2 1 4 4 4 0 Uncharacterised protein family (UPF0242) N-terminus SPC22 PF04573.12 AIN96779.1 - 5.4e-17 61.8 0.3 3.9e-10 39.5 0.0 3.1 3 0 0 3 3 3 3 Signal peptidase subunit DUF2830 PF11125.8 AIN96779.1 - 1.3 9.0 0.0 1.3 9.0 0.0 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF2830) FAM183 PF14886.6 AIN96780.1 - 0.011 16.4 0.5 0.032 14.9 0.5 2.1 1 1 0 1 1 1 0 FAM183A and FAM183B related DUF4429 PF14472.6 AIN96780.1 - 0.015 15.9 0.5 3.2 8.4 0.1 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4429) MDH PF02315.16 AIN96780.1 - 0.087 12.9 0.1 0.17 12.0 0.1 1.4 1 0 0 1 1 1 0 Methanol dehydrogenase beta subunit CRAL_TRIO PF00650.20 AIN96783.1 - 4e-18 65.6 0.0 1.8e-15 57.0 0.0 2.8 2 1 0 2 2 2 2 CRAL/TRIO domain ESR1_C PF12743.7 AIN96784.1 - 0.012 15.3 2.7 0.014 15.2 0.6 2.3 2 0 0 2 2 2 0 Oestrogen-type nuclear receptor final C-terminal Dynamin_M PF01031.20 AIN96785.1 - 0.57 9.3 2.2 0.97 8.6 2.2 1.3 1 0 0 1 1 1 0 Dynamin central region DUF842 PF05811.13 AIN96785.1 - 3.7 7.3 11.8 0.18 11.5 5.3 2.0 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF842) Kelch_4 PF13418.6 AIN96786.1 - 2.9e-20 72.0 1.4 2.4e-05 24.3 0.0 6.8 6 0 0 6 6 6 3 Galactose oxidase, central domain Kelch_5 PF13854.6 AIN96786.1 - 7.4e-18 64.1 2.2 0.0017 18.3 0.0 5.7 5 0 0 5 5 5 4 Kelch motif Kelch_6 PF13964.6 AIN96786.1 - 6.6e-15 54.8 2.1 5.5e-07 29.7 0.1 3.9 3 0 0 3 3 3 2 Kelch motif Kelch_3 PF13415.6 AIN96786.1 - 6.4e-14 51.8 4.0 0.00058 20.1 0.1 6.4 5 0 0 5 5 5 3 Galactose oxidase, central domain Kelch_2 PF07646.15 AIN96786.1 - 5.5e-13 48.3 3.4 0.00023 21.0 0.0 4.1 3 0 0 3 3 3 3 Kelch motif Kelch_1 PF01344.25 AIN96786.1 - 2.1e-08 33.6 7.8 0.015 14.9 0.1 4.2 4 0 0 4 4 4 3 Kelch motif Ipi1_N PF12333.8 AIN96789.1 - 2.2e-05 24.9 0.1 0.0085 16.7 0.1 3.7 2 0 0 2 2 2 1 Rix1 complex component involved in 60S ribosome maturation V-ATPase_H_C PF11698.8 AIN96789.1 - 0.2 11.8 0.0 0.39 10.8 0.0 1.5 1 0 0 1 1 1 0 V-ATPase subunit H Cmc1 PF08583.10 AIN96790.1 - 0.00032 20.6 1.4 0.00032 20.6 1.4 2.2 2 0 0 2 2 2 1 Cytochrome c oxidase biogenesis protein Cmc1 like IucA_IucC PF04183.12 AIN96790.1 - 0.13 11.8 0.0 0.18 11.4 0.0 1.2 1 0 0 1 1 1 0 IucA / IucC family UPF0203 PF05254.12 AIN96790.1 - 0.41 10.9 6.9 0.095 13.0 1.4 2.6 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0203) Sec5 PF15469.6 AIN96790.1 - 0.56 10.0 5.0 3.6 7.4 0.4 2.6 2 1 1 3 3 3 0 Exocyst complex component Sec5 tRNA_SAD PF07973.14 AIN96791.1 - 0.0012 18.8 0.3 0.022 14.9 0.1 2.7 2 1 0 2 2 2 1 Threonyl and Alanyl tRNA synthetase second additional domain tRNA-synt_2c PF01411.19 AIN96791.1 - 0.01 14.4 0.0 0.014 13.9 0.0 1.2 1 0 0 1 1 1 0 tRNA synthetases class II (A) NMT_C PF02799.15 AIN96791.1 - 0.11 12.0 0.0 0.21 11.1 0.0 1.3 1 0 0 1 1 1 0 Myristoyl-CoA:protein N-myristoyltransferase, C-terminal domain DUF1659 PF07872.11 AIN96792.1 - 0.021 14.5 0.3 0.13 11.9 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1659) TPR_10 PF13374.6 AIN96793.1 - 0.068 13.1 0.1 0.53 10.2 0.1 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat FAD_binding_3 PF01494.19 AIN96794.1 - 2e-06 27.3 0.1 7e-06 25.5 0.1 1.9 1 1 0 1 1 1 1 FAD binding domain Methyltransf_16 PF10294.9 AIN96795.1 - 1.3e-09 38.0 0.0 7.3e-06 25.8 0.0 2.1 2 0 0 2 2 2 2 Lysine methyltransferase ABC_tran PF00005.27 AIN96796.1 - 2.9e-55 186.5 0.0 9e-29 100.7 0.0 3.3 3 0 0 3 3 3 2 ABC transporter ABC2_membrane_3 PF12698.7 AIN96796.1 - 1.2e-47 162.8 56.2 3.5e-35 121.7 22.7 2.9 2 1 0 2 2 2 2 ABC-2 family transporter protein AAA_21 PF13304.6 AIN96796.1 - 2.5e-24 86.6 0.4 4.1e-09 36.7 0.0 4.4 4 0 0 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 AIN96796.1 - 5e-08 32.6 0.0 0.55 9.6 0.0 4.1 4 0 0 4 4 4 3 RecF/RecN/SMC N terminal domain DUF4162 PF13732.6 AIN96796.1 - 2.4e-07 31.3 0.0 0.0013 19.4 0.0 3.4 3 0 0 3 3 3 1 Domain of unknown function (DUF4162) AAA_29 PF13555.6 AIN96796.1 - 9.3e-06 25.3 0.6 0.0038 16.9 0.0 2.7 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_23 PF13476.6 AIN96796.1 - 0.00021 21.9 0.5 0.1 13.1 0.0 2.3 2 0 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 AIN96796.1 - 0.00086 19.2 0.0 1.2 9.0 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA_15 PF13175.6 AIN96796.1 - 0.00095 19.0 0.0 0.76 9.4 0.0 3.1 3 0 0 3 3 3 1 AAA ATPase domain AAA_30 PF13604.6 AIN96796.1 - 0.038 13.7 0.0 0.64 9.7 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 AIN96796.1 - 0.041 14.3 0.0 1.4 9.3 0.0 2.9 2 0 0 2 2 2 0 AAA ATPase domain Zeta_toxin PF06414.12 AIN96796.1 - 0.059 12.6 0.1 6.4 6.0 0.0 2.9 3 0 0 3 3 3 0 Zeta toxin Mg_chelatase PF01078.21 AIN96796.1 - 0.063 12.7 0.1 2.3 7.6 0.0 3.2 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI AAA_22 PF13401.6 AIN96796.1 - 0.12 12.6 0.0 1.3 9.2 0.0 2.7 3 0 0 3 3 3 0 AAA domain ABC2_membrane_2 PF12679.7 AIN96796.1 - 0.98 8.6 30.4 0.03 13.6 12.5 2.8 2 0 0 2 2 2 0 ABC-2 family transporter protein DUF2871 PF11070.8 AIN96798.1 - 8.9e-42 142.6 11.0 1e-41 142.4 11.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2871) TrbC PF04956.13 AIN96798.1 - 0.037 14.3 2.7 0.12 12.6 2.7 1.8 1 1 0 1 1 1 0 TrbC/VIRB2 family Tetraspanin PF00335.20 AIN96798.1 - 0.053 13.2 2.5 0.064 13.0 2.5 1.2 1 0 0 1 1 1 0 Tetraspanin family Pkinase PF00069.25 AIN96799.1 - 3.4e-25 88.9 0.0 4.8e-25 88.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 AIN96799.1 - 1.7e-10 40.6 0.0 2.7e-10 40.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 AIN96799.1 - 0.00099 18.5 0.0 0.0021 17.4 0.0 1.5 2 0 0 2 2 2 1 Kinase-like Pex16 PF08610.10 AIN96803.1 - 2.3e-14 53.3 0.0 8.3e-12 44.9 0.0 2.4 2 0 0 2 2 2 2 Peroxisomal membrane protein (Pex16) DPM2 PF07297.12 AIN96804.1 - 1.3e-16 60.7 0.7 1.9e-16 60.1 0.7 1.3 1 0 0 1 1 1 1 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) GDI PF00996.18 AIN96805.1 - 3.1e-21 75.4 0.0 1.6e-09 36.8 0.0 3.1 2 1 0 2 2 2 2 GDP dissociation inhibitor Methyltransf_16 PF10294.9 AIN96805.1 - 5e-11 42.6 0.0 0.00012 21.8 0.0 2.3 2 0 0 2 2 2 2 Lysine methyltransferase MTS PF05175.14 AIN96805.1 - 0.079 12.5 0.1 0.98 8.9 0.1 2.4 1 1 1 2 2 2 0 Methyltransferase small domain UPF0060 PF02694.15 AIN96805.1 - 0.087 13.1 0.1 0.25 11.6 0.1 1.7 1 0 0 1 1 1 0 Uncharacterised BCR, YnfA/UPF0060 family AIP3 PF03915.13 AIN96807.1 - 5.6 5.9 12.8 0.28 10.2 3.4 2.3 2 0 0 2 2 2 0 Actin interacting protein 3 MFS_1 PF07690.16 AIN96810.1 - 2.6e-15 56.2 32.2 6.7e-12 45.0 13.0 2.2 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 AIN96810.1 - 1.5e-07 30.6 5.1 1.5e-07 30.6 5.1 2.5 2 1 0 2 2 2 2 Sugar (and other) transporter Inositol_P PF00459.25 AIN96811.1 - 3.3e-43 148.2 0.9 1.9e-21 76.8 0.1 2.2 2 0 0 2 2 2 2 Inositol monophosphatase family Kdo_hydroxy PF11004.8 AIN96811.1 - 0.14 11.4 0.0 0.23 10.7 0.0 1.2 1 0 0 1 1 1 0 3-deoxy-D-manno-oct-2-ulosonic acid (Kdo) hydroxylase DUF4897 PF16238.5 AIN96811.1 - 0.21 11.4 0.0 0.4 10.5 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4897) TFIIA PF03153.13 AIN96811.1 - 5.1 7.0 6.8 3.2 7.6 4.3 1.7 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit TrbI PF03743.14 AIN96811.1 - 9.4 6.0 7.3 2.9 7.7 0.2 2.2 2 0 0 2 2 2 0 Bacterial conjugation TrbI-like protein ABC2_membrane PF01061.24 AIN96812.1 - 6.3e-39 133.6 18.7 6.3e-39 133.6 18.7 1.6 2 0 0 2 2 2 1 ABC-2 type transporter ABC_tran PF00005.27 AIN96812.1 - 7.2e-19 68.7 0.0 1.2e-18 68.0 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_16 PF13191.6 AIN96812.1 - 0.0033 17.8 0.0 0.0066 16.8 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain RsgA_GTPase PF03193.16 AIN96812.1 - 0.0039 17.1 0.0 0.0069 16.3 0.0 1.3 1 0 0 1 1 1 1 RsgA GTPase AAA_22 PF13401.6 AIN96812.1 - 0.0056 17.0 0.0 0.012 15.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_23 PF13476.6 AIN96812.1 - 0.013 16.1 0.1 0.022 15.3 0.1 1.3 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 AIN96812.1 - 0.017 14.9 0.5 0.035 13.8 0.5 1.4 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 AIN96812.1 - 0.022 14.5 0.3 0.053 13.3 0.3 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain PRK PF00485.18 AIN96812.1 - 0.059 13.1 0.0 0.095 12.4 0.0 1.3 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family RNA_helicase PF00910.22 AIN96812.1 - 0.073 13.5 0.0 0.52 10.7 0.0 2.1 2 0 0 2 2 2 0 RNA helicase AAA_21 PF13304.6 AIN96812.1 - 0.075 12.8 0.2 12 5.6 0.0 2.3 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system NACHT PF05729.12 AIN96812.1 - 0.076 12.9 0.0 0.18 11.7 0.0 1.6 1 0 0 1 1 1 0 NACHT domain SMC_N PF02463.19 AIN96812.1 - 0.086 12.3 0.0 8.4 5.8 0.0 2.2 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_18 PF13238.6 AIN96812.1 - 0.11 13.1 0.0 0.23 12.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.22 AIN96812.1 - 0.11 11.6 0.0 0.17 11.0 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain MMR_HSR1 PF01926.23 AIN96812.1 - 0.13 12.4 0.0 0.24 11.5 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_14 PF13173.6 AIN96812.1 - 0.13 12.3 0.0 0.32 11.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 AIN96812.1 - 0.18 11.5 0.5 0.45 10.2 0.5 1.6 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 AIN96812.1 - 0.19 11.1 0.2 1.1 8.6 0.0 2.1 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI ABC2_membrane_3 PF12698.7 AIN96812.1 - 2.1 7.4 19.7 0.13 11.3 14.4 1.6 2 0 0 2 2 2 0 ABC-2 family transporter protein HEAT PF02985.22 AIN96815.1 - 1e-18 65.8 25.9 0.0016 18.5 0.0 10.5 10 0 0 10 10 10 7 HEAT repeat HEAT_2 PF13646.6 AIN96815.1 - 8.7e-18 64.5 18.0 7.4e-05 23.1 1.8 6.7 3 2 4 7 7 7 7 HEAT repeats Adaptin_N PF01602.20 AIN96815.1 - 0.00018 20.2 3.0 2.7 6.4 0.0 3.6 4 1 0 4 4 4 3 Adaptin N terminal region Cnd1 PF12717.7 AIN96815.1 - 0.00065 19.8 2.4 0.39 10.7 0.1 4.2 4 1 0 4 4 4 1 non-SMC mitotic condensation complex subunit 1 CLASP_N PF12348.8 AIN96815.1 - 0.0034 17.0 3.3 0.57 9.7 0.1 3.7 3 2 1 4 4 4 1 CLASP N terminal Nipped-B_C PF12830.7 AIN96815.1 - 0.19 11.6 0.2 12 5.8 0.0 2.6 2 0 0 2 2 2 0 Sister chromatid cohesion C-terminus Cohesin_HEAT PF12765.7 AIN96815.1 - 0.42 11.0 2.5 0.95 9.8 0.1 2.7 2 0 0 2 2 2 0 HEAT repeat associated with sister chromatid cohesion EF-hand_8 PF13833.6 AIN96816.1 - 1.4e-07 31.3 0.0 0.1 12.5 0.0 3.1 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_9 PF14658.6 AIN96816.1 - 5.8e-07 29.7 0.1 0.055 13.8 0.0 3.1 2 1 1 3 3 3 2 EF-hand domain EF-hand_7 PF13499.6 AIN96816.1 - 1.2e-06 28.8 0.0 0.00017 22.0 0.0 2.2 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.6 AIN96816.1 - 3e-05 23.6 0.2 0.34 10.9 0.0 3.9 5 0 0 5 5 5 2 EF-hand domain EF-hand_1 PF00036.32 AIN96816.1 - 0.007 15.8 0.0 8.9 6.1 0.0 3.6 3 0 0 3 3 3 1 EF hand Retrotran_gag_2 PF14223.6 AIN96816.1 - 0.01 15.5 0.1 3.5 7.3 0.1 2.7 2 1 1 3 3 3 0 gag-polypeptide of LTR copia-type DUF2267 PF10025.9 AIN96816.1 - 0.011 16.0 0.3 2.1 8.7 0.1 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2267) DUF2087 PF09860.9 AIN96816.1 - 0.019 15.1 0.0 1.4 9.1 0.0 2.4 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2087) MAP65_ASE1 PF03999.12 AIN96817.1 - 1.7e-06 27.0 5.4 1.7e-06 27.0 5.4 3.5 5 1 0 5 5 5 1 Microtubule associated protein (MAP65/ASE1 family) Herpes_UL6 PF01763.16 AIN96817.1 - 0.013 14.1 0.2 0.025 13.1 0.2 1.4 1 0 0 1 1 1 0 Herpesvirus UL6 like DUF5526 PF17664.1 AIN96817.1 - 1.6 8.3 11.0 0.023 14.2 1.2 2.6 2 0 0 2 2 2 0 Family of unknown function (DUF5526) Ribosomal_S3_C PF00189.20 AIN96818.1 - 1.4e-19 70.4 1.8 1.4e-19 70.4 1.8 2.2 2 1 1 3 3 3 1 Ribosomal protein S3, C-terminal domain KH_2 PF07650.17 AIN96818.1 - 1.8e-07 30.9 0.3 5e-07 29.5 0.3 1.7 2 0 0 2 2 2 1 KH domain Evr1_Alr PF04777.13 AIN96819.1 - 1e-22 80.4 1.7 2.1e-22 79.4 1.7 1.5 1 0 0 1 1 1 1 Erv1 / Alr family Get5_C PF18514.1 AIN96819.1 - 0.12 12.1 0.0 0.29 10.9 0.0 1.7 1 0 0 1 1 1 0 Get5 C-terminal domain ThiF PF00899.21 AIN96820.1 - 3.7e-49 167.3 0.0 5.3e-49 166.8 0.0 1.1 1 0 0 1 1 1 1 ThiF family PglD_N PF17836.1 AIN96820.1 - 0.0016 19.1 0.0 0.0033 18.0 0.0 1.6 1 0 0 1 1 1 1 PglD N-terminal domain 2-Hacid_dh_C PF02826.19 AIN96820.1 - 0.0038 16.6 0.0 0.0083 15.5 0.0 1.6 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.14 AIN96820.1 - 0.012 15.2 0.0 0.018 14.6 0.0 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain ApbA PF02558.16 AIN96820.1 - 0.012 15.3 0.1 0.037 13.7 0.1 1.8 1 1 0 1 1 1 0 Ketopantoate reductase PanE/ApbA FAD_binding_3 PF01494.19 AIN96820.1 - 0.023 13.9 0.3 0.047 12.9 0.3 1.5 1 0 0 1 1 1 0 FAD binding domain Sacchrp_dh_NADP PF03435.18 AIN96820.1 - 0.039 14.2 0.9 0.078 13.2 0.0 2.0 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain Shikimate_DH PF01488.20 AIN96820.1 - 0.065 13.3 0.0 0.15 12.1 0.0 1.6 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Rad9 PF04139.13 AIN96821.1 - 4.6e-08 32.8 0.0 6e-05 22.6 0.0 2.4 2 1 0 2 2 2 2 Rad9 LD_cluster3 PF18180.1 AIN96821.1 - 0.17 11.5 0.1 0.43 10.2 0.1 1.6 1 0 0 1 1 1 0 SLOG cluster3 family Fer4_17 PF13534.6 AIN96822.1 - 4.2e-08 33.6 8.8 1.8e-06 28.4 0.8 1.8 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_8 PF13183.6 AIN96822.1 - 2.2e-07 31.2 0.3 0.00051 20.4 0.3 2.2 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_10 PF13237.6 AIN96822.1 - 0.00019 21.5 4.5 0.00054 20.0 4.5 1.7 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_9 PF13187.6 AIN96822.1 - 0.0056 16.8 4.3 0.037 14.2 1.4 2.1 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_4 PF12800.7 AIN96822.1 - 0.013 16.0 5.0 0.047 14.2 1.0 2.3 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_7 PF12838.7 AIN96822.1 - 0.073 13.7 4.3 0.33 11.6 4.5 1.9 1 1 0 1 1 1 0 4Fe-4S dicluster domain Ribosomal_L6e PF01159.19 AIN96823.1 - 2.2e-28 99.0 0.7 1.5e-27 96.3 0.7 2.0 1 1 0 1 1 1 1 Ribosomal protein L6e KOW PF00467.29 AIN96823.1 - 0.00037 20.4 0.0 0.0015 18.4 0.0 2.1 1 1 1 2 2 2 1 KOW motif ParE-like_toxin PF15781.5 AIN96823.1 - 0.61 10.1 3.2 2.9 7.9 3.2 2.1 1 1 0 1 1 1 0 ParE-like toxin of type II bacterial toxin-antitoxin system OAD_gamma PF04277.13 AIN96823.1 - 7.1 7.3 10.8 0.78 10.4 5.5 2.0 2 0 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain ELFV_dehydrog PF00208.21 AIN96824.1 - 2e-48 165.2 0.0 3.6e-48 164.4 0.0 1.4 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Bac_GDH PF05088.12 AIN96824.1 - 4.8e-17 60.9 0.0 2e-08 32.3 0.0 2.2 2 0 0 2 2 2 2 Bacterial NAD-glutamate dehydrogenase CLP1_N PF16573.5 AIN96824.1 - 0.15 12.3 0.1 1.4 9.2 0.0 2.3 2 0 0 2 2 2 0 N-terminal beta-sandwich domain of polyadenylation factor polyprenyl_synt PF00348.17 AIN96825.1 - 4.8e-63 212.6 0.0 5.9e-63 212.3 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase SQS_PSY PF00494.19 AIN96825.1 - 0.012 15.2 0.4 0.038 13.5 0.1 2.0 2 0 0 2 2 2 0 Squalene/phytoene synthase SKIP_SNW PF02731.15 AIN96826.1 - 4.1e-09 36.3 2.7 4.1e-09 36.3 2.7 2.6 1 1 1 2 2 2 1 SKIP/SNW domain RR_TM4-6 PF06459.12 AIN96826.1 - 3.7 7.3 9.9 7.8 6.2 9.9 1.5 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 GREB1 PF15782.5 AIN96826.1 - 7.6 3.5 6.5 8.2 3.4 6.5 1.2 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Presenilin PF01080.17 AIN96826.1 - 8.9 5.0 5.8 15 4.2 5.8 1.3 1 0 0 1 1 1 0 Presenilin AhpC-TSA PF00578.21 AIN96827.1 - 1.9e-36 124.7 0.0 2.6e-36 124.3 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 AIN96827.1 - 3.4e-14 52.8 0.0 4.1e-14 52.5 0.0 1.1 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.9 AIN96827.1 - 4.3e-13 48.9 0.0 9.2e-13 47.8 0.0 1.6 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin SCO1-SenC PF02630.14 AIN96827.1 - 0.078 12.9 0.0 0.2 11.6 0.0 1.6 2 0 0 2 2 2 0 SCO1/SenC AhpC-TSA PF00578.21 AIN96829.1 - 2.4e-38 130.8 0.0 3.1e-38 130.5 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 AIN96829.1 - 1.8e-15 56.9 0.0 2.2e-15 56.7 0.0 1.1 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.9 AIN96829.1 - 5.3e-13 48.6 0.0 1.2e-12 47.4 0.0 1.7 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin SCO1-SenC PF02630.14 AIN96829.1 - 0.02 14.8 0.1 0.051 13.5 0.0 1.6 2 0 0 2 2 2 0 SCO1/SenC TFIIB_C_1 PF18542.1 AIN96830.1 - 6e-42 141.6 1.3 6e-42 141.6 1.3 1.9 2 0 0 2 2 2 1 Transcription factor IIB C-terminal module 1 TF_Zn_Ribbon PF08271.12 AIN96830.1 - 3.3e-06 26.5 1.3 6.5e-06 25.6 1.3 1.4 1 0 0 1 1 1 1 TFIIB zinc-binding zf-ribbon_3 PF13248.6 AIN96830.1 - 0.14 11.6 2.0 0.68 9.4 0.3 2.4 2 0 0 2 2 2 0 zinc-ribbon domain DUF29 PF01724.16 AIN96830.1 - 0.15 12.3 0.0 0.33 11.2 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function DUF29 Lar_restr_allev PF14354.6 AIN96830.1 - 0.3 11.5 2.3 0.48 10.8 0.6 2.1 2 0 0 2 2 2 0 Restriction alleviation protein Lar MSA-2c PF12238.8 AIN96830.1 - 0.33 10.9 1.4 0.61 10.0 1.4 1.4 1 0 0 1 1 1 0 Merozoite surface antigen 2c cNMP_binding PF00027.29 AIN96832.1 - 0.00059 19.8 0.0 0.0093 16.0 0.0 2.7 2 0 0 2 2 2 1 Cyclic nucleotide-binding domain Pkinase PF00069.25 AIN96833.1 - 6e-57 193.0 0.0 9.3e-57 192.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 AIN96833.1 - 2e-39 135.4 0.0 3.5e-39 134.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase cNMP_binding PF00027.29 AIN96833.1 - 1.5e-29 101.9 0.4 1.2e-14 54.1 0.1 3.1 3 0 0 3 3 3 2 Cyclic nucleotide-binding domain Kinase-like PF14531.6 AIN96833.1 - 6.7e-08 32.2 0.0 2.1e-06 27.3 0.0 2.3 2 0 0 2 2 2 1 Kinase-like PAS PF00989.25 AIN96833.1 - 3.9e-07 30.0 0.0 1.4e-06 28.3 0.0 2.0 1 0 0 1 1 1 1 PAS fold PAS_9 PF13426.7 AIN96833.1 - 1.5e-06 28.4 0.0 9e-05 22.7 0.0 2.7 2 0 0 2 2 2 1 PAS domain RIO1 PF01163.22 AIN96833.1 - 0.18 11.4 0.0 0.4 10.2 0.0 1.5 1 0 0 1 1 1 0 RIO1 family Ribosomal_60s PF00428.19 AIN96834.1 - 2.6e-22 79.2 13.3 3.3e-22 78.9 13.3 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein Phage-MuB_C PF09077.11 AIN96834.1 - 0.015 15.2 3.4 0.027 14.3 3.4 1.6 1 1 0 1 1 1 0 Mu B transposition protein, C terminal Ribosomal_60s PF00428.19 AIN96835.1 - 2.6e-22 79.2 13.3 3.3e-22 78.9 13.3 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein Phage-MuB_C PF09077.11 AIN96835.1 - 0.015 15.2 3.4 0.027 14.3 3.4 1.6 1 1 0 1 1 1 0 Mu B transposition protein, C terminal RhoGAP PF00620.27 AIN96836.1 - 7.6e-12 45.3 0.0 1.5e-11 44.4 0.0 1.4 1 0 0 1 1 1 1 RhoGAP domain Exo_endo_phos PF03372.23 AIN96836.1 - 3.8e-08 33.1 0.2 1.2e-07 31.5 0.0 1.9 2 0 0 2 2 2 1 Endonuclease/Exonuclease/phosphatase family DnaJ PF00226.31 AIN96837.1 - 3e-25 88.1 1.0 4.6e-25 87.5 1.0 1.3 1 0 0 1 1 1 1 DnaJ domain DnaJ_C PF01556.18 AIN96837.1 - 1e-18 67.8 0.0 8.1e-18 64.9 0.0 2.0 1 1 0 1 1 1 1 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.19 AIN96837.1 - 8.1e-07 29.3 13.6 1.7e-06 28.3 13.6 1.5 1 0 0 1 1 1 1 DnaJ central domain SabA_adhesion PF18304.1 AIN96837.1 - 0.16 11.2 0.1 0.28 10.4 0.1 1.3 1 0 0 1 1 1 0 SabA N-terminal extracellular adhesion domain Anti-TRAP PF15777.5 AIN96837.1 - 0.85 9.6 15.4 0.095 12.7 4.2 2.7 2 0 0 2 2 2 0 Tryptophan RNA-binding attenuator protein inhibitory protein Nucleoside_tran PF01733.18 AIN96838.1 - 9.1e-33 113.9 1.3 1.7e-32 113.0 1.3 1.4 1 0 0 1 1 1 1 Nucleoside transporter DUF2177 PF09945.9 AIN96838.1 - 0.0035 17.4 0.4 0.014 15.5 0.4 2.1 1 0 0 1 1 1 1 Predicted membrane protein (DUF2177) UFC1 PF08694.11 AIN96839.1 - 5.8e-78 259.9 0.1 6.6e-78 259.7 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin-fold modifier-conjugating enzyme 1 UQ_con PF00179.26 AIN96839.1 - 0.00054 19.6 0.2 0.00073 19.2 0.2 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 AIN96839.1 - 0.0093 16.2 0.0 0.012 15.9 0.0 1.2 1 0 0 1 1 1 1 RWD domain SET PF00856.28 AIN96840.1 - 3.8e-08 33.9 0.0 8.9e-08 32.7 0.0 1.6 1 1 0 1 1 1 1 SET domain Di19_C PF14571.6 AIN96841.1 - 0.021 15.3 0.3 0.05 14.1 0.3 1.6 1 0 0 1 1 1 0 Stress-induced protein Di19, C-terminal Chorion_3 PF05387.11 AIN96841.1 - 0.27 10.8 2.5 0.44 10.1 2.5 1.2 1 0 0 1 1 1 0 Chorion family 3 Herpes_capsid PF06112.11 AIN96841.1 - 6.7 6.7 11.9 16 5.5 11.9 1.5 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein IQ PF00612.27 AIN96842.1 - 5 7.2 31.2 0.93 9.5 1.1 5.8 5 0 0 5 5 5 0 IQ calmodulin-binding motif DNA_topoisoIV PF00521.20 AIN96843.1 - 5.2e-102 341.9 0.0 8.1e-102 341.3 0.0 1.3 1 0 0 1 1 1 1 DNA gyrase/topoisomerase IV, subunit A TOPRIM_C PF16898.5 AIN96843.1 - 6.5e-32 110.5 1.2 1.4e-31 109.5 1.2 1.6 1 0 0 1 1 1 1 C-terminal associated domain of TOPRIM DNA_gyraseB PF00204.25 AIN96843.1 - 3.2e-09 36.5 0.0 7.4e-09 35.3 0.0 1.6 1 0 0 1 1 1 1 DNA gyrase B HATPase_c PF02518.26 AIN96843.1 - 1.1e-08 35.5 0.0 3.8e-08 33.8 0.0 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Toprim PF01751.22 AIN96843.1 - 1.8e-06 28.1 0.0 7.6e-06 26.1 0.0 2.1 1 0 0 1 1 1 1 Toprim domain SAB PF04382.13 AIN96843.1 - 0.038 14.1 0.2 0.11 12.6 0.2 1.8 1 0 0 1 1 1 0 SAB domain UCH PF00443.29 AIN96844.1 - 1.8e-38 132.5 0.0 2.7e-38 131.9 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase USP7_ICP0_bdg PF12436.8 AIN96844.1 - 4.7e-11 42.5 0.0 6e-06 25.7 0.0 3.0 2 1 0 2 2 2 2 ICP0-binding domain of Ubiquitin-specific protease 7 UCH_1 PF13423.6 AIN96844.1 - 8.7e-09 35.4 0.0 0.0028 17.3 0.0 2.7 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase Pol_alpha_B_N PF08418.10 AIN96844.1 - 2.4 8.0 5.9 2.3 8.1 4.2 1.7 2 0 0 2 2 2 0 DNA polymerase alpha subunit B N-terminal CorA PF01544.18 AIN96845.1 - 9.2e-23 81.0 8.4 1.6e-20 73.6 8.4 2.2 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein SHOCT PF09851.9 AIN96845.1 - 8.4e-05 22.2 0.0 0.00015 21.4 0.0 1.4 1 0 0 1 1 1 1 Short C-terminal domain MIF4G PF02854.19 AIN96846.1 - 6.1e-11 42.4 0.1 1.1e-10 41.6 0.1 1.4 1 0 0 1 1 1 1 MIF4G domain Actin PF00022.19 AIN96847.1 - 2.8e-99 332.5 0.0 4e-99 332.0 0.0 1.2 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.13 AIN96847.1 - 0.00059 18.7 0.1 0.091 11.6 0.0 2.3 2 0 0 2 2 2 2 MreB/Mbl protein NIF PF03031.18 AIN96849.1 - 0.022 14.5 0.0 0.046 13.5 0.0 1.6 1 0 0 1 1 1 0 NLI interacting factor-like phosphatase WHEP-TRS PF00458.20 AIN96850.1 - 0.11 12.6 1.0 0.26 11.5 1.0 1.6 1 0 0 1 1 1 0 WHEP-TRS domain PPR_long PF17177.4 AIN96850.1 - 0.14 11.5 0.1 0.28 10.5 0.1 1.4 1 0 0 1 1 1 0 Pentacotripeptide-repeat region of PRORP RabGAP-TBC PF00566.18 AIN96851.1 - 3.5e-06 26.8 0.2 7.1e-06 25.8 0.2 1.4 1 0 0 1 1 1 1 Rab-GTPase-TBC domain SlyX PF04102.12 AIN96851.1 - 0.033 14.8 0.4 0.11 13.1 0.4 1.9 1 0 0 1 1 1 0 SlyX DUF2633 PF11119.8 AIN96851.1 - 1.5 8.8 4.7 4.8 7.2 0.8 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF2633) 2OG-FeII_Oxy PF03171.20 AIN96852.1 - 0.001 19.5 0.0 0.093 13.2 0.0 2.4 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Actin PF00022.19 AIN96853.1 - 5.7e-68 229.4 0.0 5.9e-66 222.7 0.0 2.0 1 1 0 1 1 1 1 Actin FtsA PF14450.6 AIN96853.1 - 0.029 14.8 0.0 0.33 11.4 0.0 2.2 2 0 0 2 2 2 0 Cell division protein FtsA DUF1796 PF08795.10 AIN96854.1 - 1.5e-48 164.9 0.0 2.6e-48 164.2 0.0 1.4 1 0 0 1 1 1 1 Putative papain-like cysteine peptidase (DUF1796) Nop PF01798.18 AIN96855.1 - 1e-81 273.8 0.6 1.4e-81 273.4 0.6 1.2 1 0 0 1 1 1 1 snoRNA binding domain, fibrillarin NOP5NT PF08156.13 AIN96855.1 - 0.00014 22.2 0.5 0.17 12.3 0.1 2.8 1 1 1 2 2 2 2 NOP5NT (NUC127) domain TMEM164 PF14808.6 AIN96856.1 - 7.7e-10 38.5 4.0 1.1e-09 38.1 4.0 1.3 1 0 0 1 1 1 1 TMEM164 family Peptidase_U4 PF03419.13 AIN96856.1 - 4 6.6 6.1 26 4.0 5.8 2.4 1 1 1 2 2 2 0 Sporulation factor SpoIIGA zf-RING_2 PF13639.6 AIN96858.1 - 1.8e-12 47.4 8.4 3.7e-12 46.4 8.4 1.6 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 AIN96858.1 - 9.2e-07 28.8 6.4 1.7e-06 28.0 6.4 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 AIN96858.1 - 1.3e-06 28.1 8.3 2.5e-06 27.2 8.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 AIN96858.1 - 1.9e-06 27.5 3.3 4e-06 26.4 3.3 1.5 1 0 0 1 1 1 1 RING-like zinc finger zf-rbx1 PF12678.7 AIN96858.1 - 7.1e-06 26.2 9.6 2.3e-05 24.6 9.6 1.8 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_3 PF13920.6 AIN96858.1 - 1.8e-05 24.5 6.3 3.2e-05 23.7 6.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 AIN96858.1 - 0.00019 21.2 7.7 0.00035 20.4 7.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 AIN96858.1 - 0.0004 20.3 6.5 0.00074 19.4 6.5 1.5 1 0 0 1 1 1 1 zinc-RING finger domain FANCL_C PF11793.8 AIN96858.1 - 0.017 15.3 8.0 0.34 11.1 8.0 2.4 1 1 0 1 1 1 0 FANCL C-terminal domain Prok-RING_4 PF14447.6 AIN96858.1 - 0.028 14.3 5.5 0.059 13.3 5.5 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-ANAPC11 PF12861.7 AIN96858.1 - 0.038 14.0 5.1 0.11 12.6 5.1 1.8 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger DUF5337 PF17272.2 AIN96858.1 - 0.064 13.1 0.2 0.064 13.1 0.2 2.6 3 0 0 3 3 3 0 Family of unknown function (DUF5337) Nucleo_P87 PF07267.11 AIN96858.1 - 0.099 11.5 0.3 0.13 11.1 0.3 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Zn_ribbon_17 PF17120.5 AIN96858.1 - 0.1 12.2 4.7 0.21 11.2 4.7 1.5 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zinc_ribbon_16 PF17034.5 AIN96858.1 - 0.19 11.9 1.4 0.39 10.9 1.4 1.4 1 0 0 1 1 1 0 Zinc-ribbon like family zf-RING_4 PF14570.6 AIN96858.1 - 0.46 10.3 7.5 0.9 9.4 7.5 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain MutS_V PF00488.21 AIN96859.1 - 1.5e-49 168.6 0.0 2e-48 164.9 0.0 2.2 1 1 0 1 1 1 1 MutS domain V MutS_III PF05192.18 AIN96859.1 - 2.4e-21 76.8 0.1 4e-21 76.1 0.1 1.4 1 0 0 1 1 1 1 MutS domain III MutS_I PF01624.20 AIN96859.1 - 7e-20 71.4 0.0 1.2e-19 70.6 0.0 1.4 1 0 0 1 1 1 1 MutS domain I MutS_IV PF05190.18 AIN96859.1 - 0.02 15.2 0.0 0.04 14.3 0.0 1.5 1 0 0 1 1 1 0 MutS family domain IV tRNA-synt_1c PF00749.21 AIN96861.1 - 2.3e-104 348.7 0.0 3.1e-104 348.3 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.18 AIN96861.1 - 1.8e-39 135.4 0.0 3e-39 134.7 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain PCNA_N PF00705.18 AIN96862.1 - 8.3e-42 141.9 2.1 1.2e-41 141.4 1.3 1.6 2 0 0 2 2 2 1 Proliferating cell nuclear antigen, N-terminal domain PCNA_C PF02747.15 AIN96862.1 - 2.5e-37 127.9 0.1 1.9e-19 70.1 0.2 2.4 2 0 0 2 2 2 2 Proliferating cell nuclear antigen, C-terminal domain Rad9 PF04139.13 AIN96862.1 - 7.3e-08 32.2 0.1 1.1e-07 31.6 0.1 1.2 1 0 0 1 1 1 1 Rad9 Rad1 PF02144.16 AIN96862.1 - 0.00031 19.9 0.4 0.0047 16.0 0.4 2.1 1 1 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 Hus1 PF04005.12 AIN96862.1 - 0.011 14.8 0.0 0.21 10.7 0.0 2.1 2 0 0 2 2 2 0 Hus1-like protein Diphthami_syn_2 PF01902.17 AIN96862.1 - 0.13 11.8 0.0 0.22 11.0 0.0 1.4 1 0 0 1 1 1 0 Diphthamide synthase GHMP_kinases_N PF00288.26 AIN96863.1 - 2.4e-13 50.1 2.8 3.1e-13 49.7 0.8 2.2 2 0 0 2 2 2 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 AIN96863.1 - 1e-05 25.8 0.3 0.00014 22.2 0.2 2.3 2 0 0 2 2 2 1 GHMP kinases C terminal Gpr1_Fun34_YaaH PF01184.19 AIN96864.1 - 0.0021 17.7 0.1 0.0026 17.4 0.1 1.1 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family ICE2 PF08426.10 AIN96864.1 - 0.0099 15.0 0.0 0.012 14.8 0.0 1.1 1 0 0 1 1 1 1 ICE2 Ribosomal_L7Ae PF01248.26 AIN96865.1 - 4e-25 87.4 0.1 4.7e-25 87.1 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family PELOTA_1 PF15608.6 AIN96865.1 - 3.3e-05 23.7 0.0 5e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 PELOTA RNA binding domain RNase_P_pop3 PF08228.11 AIN96865.1 - 0.0022 18.0 0.1 0.0026 17.9 0.1 1.1 1 0 0 1 1 1 1 RNase P subunit Pop3 PDEase_I PF00233.19 AIN96866.1 - 1.4e-69 234.4 0.0 4.9e-69 232.7 0.0 1.9 2 0 0 2 2 2 1 3'5'-cyclic nucleotide phosphodiesterase GAF PF01590.26 AIN96866.1 - 1.3e-29 103.5 0.0 1.4e-14 54.9 0.0 2.8 2 0 0 2 2 2 2 GAF domain GAF_2 PF13185.6 AIN96866.1 - 1.7e-19 70.5 0.0 7.4e-07 29.5 0.0 3.6 3 0 0 3 3 3 3 GAF domain GAF_3 PF13492.6 AIN96866.1 - 1.6e-08 35.0 0.0 0.0047 17.3 0.0 2.9 3 1 0 3 3 3 2 GAF domain Ribosomal_L11 PF00298.19 AIN96866.1 - 0.17 12.4 0.0 0.62 10.6 0.0 2.0 2 0 0 2 2 2 0 Ribosomal protein L11, RNA binding domain Glyc_hyd_38C_2 PF18230.1 AIN96867.1 - 0.035 14.2 0.5 0.24 11.5 0.3 2.4 2 0 0 2 2 2 0 Glycosyl hydrolases family 38 C-terminal sub-domain COG5 PF10392.9 AIN96869.1 - 0.044 13.9 0.1 0.069 13.3 0.1 1.4 1 0 0 1 1 1 0 Golgi transport complex subunit 5 Sld5 PF05916.11 AIN96869.1 - 0.12 12.9 0.0 0.19 12.2 0.0 1.5 1 0 0 1 1 1 0 GINS complex protein Presenilin PF01080.17 AIN96871.1 - 1e-75 255.0 31.1 3.5e-53 180.8 18.4 2.0 1 1 1 2 2 2 2 Presenilin Wyosine_form PF08608.12 AIN96872.1 - 3.2e-17 62.6 0.0 8e-17 61.3 0.0 1.7 1 0 0 1 1 1 1 Wyosine base formation Radical_SAM PF04055.21 AIN96872.1 - 1.9e-16 60.9 0.0 4e-16 59.9 0.0 1.7 1 1 0 1 1 1 1 Radical SAM superfamily Paf67 PF10255.9 AIN96872.1 - 0.097 11.6 0.0 0.15 11.0 0.0 1.2 1 0 0 1 1 1 0 RNA polymerase I-associated factor PAF67 Pkinase PF00069.25 AIN96874.1 - 1.4e-56 191.8 0.0 1.9e-56 191.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 AIN96874.1 - 1.7e-25 89.8 0.0 4.4e-25 88.4 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase FYVE PF01363.21 AIN96874.1 - 3.4e-13 49.5 5.2 8.3e-13 48.3 5.2 1.6 1 0 0 1 1 1 1 FYVE zinc finger APH PF01636.23 AIN96874.1 - 4.8e-05 23.4 0.1 0.00038 20.5 0.0 1.9 1 1 1 2 2 2 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 AIN96874.1 - 0.00029 19.8 0.0 0.0004 19.3 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase FYVE_2 PF02318.16 AIN96874.1 - 0.0017 18.6 4.2 0.0017 18.6 4.2 1.9 2 0 0 2 2 2 1 FYVE-type zinc finger Choline_kinase PF01633.20 AIN96874.1 - 0.028 14.0 0.0 0.038 13.6 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase Kinase-like PF14531.6 AIN96874.1 - 0.097 12.0 0.0 0.13 11.5 0.0 1.2 1 0 0 1 1 1 0 Kinase-like DZR PF12773.7 AIN96874.1 - 0.12 12.4 6.6 0.15 12.1 0.2 2.8 3 0 0 3 3 3 0 Double zinc ribbon zf-RING_5 PF14634.6 AIN96874.1 - 0.21 11.6 10.9 0.16 12.0 8.8 2.0 2 0 0 2 2 2 0 zinc-RING finger domain NOB1_Zn_bind PF08772.11 AIN96874.1 - 0.5 10.6 5.0 1.2 9.3 5.0 1.6 1 0 0 1 1 1 0 Nin one binding (NOB1) Zn-ribbon like Cnd1 PF12717.7 AIN96875.1 - 1.5e-18 67.4 6.0 4.4e-16 59.3 0.2 4.5 3 1 2 5 5 5 2 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 AIN96875.1 - 8.1e-06 25.7 3.7 1.2 9.6 0.0 6.1 7 0 0 7 7 7 2 HEAT repeat HEAT_2 PF13646.6 AIN96875.1 - 3.7e-05 24.0 3.1 3.4 8.1 0.1 5.3 3 2 2 5 5 5 3 HEAT repeats Cnd1_N PF12922.7 AIN96875.1 - 0.00077 19.4 0.0 0.0027 17.6 0.0 1.9 1 0 0 1 1 1 1 non-SMC mitotic condensation complex subunit 1, N-term Cnd3 PF12719.7 AIN96875.1 - 0.0041 16.4 1.1 0.03 13.5 0.1 2.6 3 0 0 3 3 3 1 Nuclear condensing complex subunits, C-term domain LEAP-2 PF07359.11 AIN96875.1 - 0.054 13.3 0.0 0.27 11.1 0.0 2.2 1 0 0 1 1 1 0 Liver-expressed antimicrobial peptide 2 precursor (LEAP-2) Nipped-B_C PF12830.7 AIN96875.1 - 0.095 12.6 1.1 10 6.0 0.0 3.7 5 0 0 5 5 5 0 Sister chromatid cohesion C-terminus SR-25 PF10500.9 AIN96876.1 - 0.0095 15.6 6.6 0.015 14.9 6.6 1.2 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein YL1 PF05764.13 AIN96876.1 - 0.096 12.8 7.9 0.19 11.8 7.9 1.4 1 0 0 1 1 1 0 YL1 nuclear protein ASF1_hist_chap PF04729.13 AIN96877.1 - 4.2e-25 88.5 0.0 5e-25 88.2 0.0 1.1 1 0 0 1 1 1 1 ASF1 like histone chaperone Ribosomal_L27A PF00828.19 AIN96878.1 - 7.3e-07 29.9 0.0 1.2e-06 29.2 0.0 1.3 1 0 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A ADK PF00406.22 AIN96879.1 - 5e-10 39.7 0.0 0.0001 22.4 0.0 2.2 1 1 1 2 2 2 2 Adenylate kinase AAA_17 PF13207.6 AIN96879.1 - 1.1e-07 32.4 0.0 4.9e-05 23.8 0.2 2.3 1 1 1 2 2 2 1 AAA domain AAA_18 PF13238.6 AIN96879.1 - 1.3e-06 29.0 0.0 2e-05 25.2 0.0 2.3 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.6 AIN96879.1 - 0.00012 22.3 0.0 0.00025 21.3 0.0 1.6 2 0 0 2 2 1 1 AAA domain Zeta_toxin PF06414.12 AIN96879.1 - 0.00032 20.0 0.2 0.0077 15.5 0.0 2.4 3 0 0 3 3 3 1 Zeta toxin cobW PF02492.19 AIN96879.1 - 0.00052 19.6 0.0 0.00076 19.1 0.0 1.2 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.6 AIN96879.1 - 0.00056 20.1 0.1 0.0018 18.5 0.1 2.0 2 1 0 2 2 1 1 AAA domain DUF5582 PF17819.1 AIN96879.1 - 0.001 19.6 0.5 0.0024 18.3 0.2 1.7 2 0 0 2 2 2 1 Family of unknown function (DUF5582) SRP54 PF00448.22 AIN96879.1 - 0.0013 18.4 0.1 0.002 17.8 0.1 1.3 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain AAA_16 PF13191.6 AIN96879.1 - 0.0013 19.1 0.1 0.0022 18.4 0.1 1.5 1 1 0 1 1 1 1 AAA ATPase domain TsaE PF02367.17 AIN96879.1 - 0.0019 18.2 0.0 0.0032 17.5 0.0 1.3 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA PF00004.29 AIN96879.1 - 0.0026 18.2 0.0 0.0042 17.5 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 AIN96879.1 - 0.0044 17.0 0.1 0.016 15.2 0.1 1.9 1 1 1 2 2 2 1 AAA domain (dynein-related subfamily) AAA_25 PF13481.6 AIN96879.1 - 0.0053 16.4 0.0 0.013 15.1 0.0 1.6 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 AIN96879.1 - 0.0061 16.5 0.1 0.011 15.6 0.1 1.4 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.6 AIN96879.1 - 0.009 16.3 0.4 0.039 14.2 0.1 2.0 1 1 1 2 2 2 1 AAA domain NTPase_1 PF03266.15 AIN96879.1 - 0.01 15.7 0.1 0.017 15.0 0.1 1.3 1 0 0 1 1 1 0 NTPase RuvB_N PF05496.12 AIN96879.1 - 0.011 15.4 0.0 0.021 14.6 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain T2SSE PF00437.20 AIN96879.1 - 0.012 14.6 0.0 0.025 13.6 0.0 1.6 1 1 0 1 1 1 0 Type II/IV secretion system protein CbiA PF01656.23 AIN96879.1 - 0.015 15.4 0.0 0.018 15.1 0.0 1.2 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain ResIII PF04851.15 AIN96879.1 - 0.02 14.9 0.0 0.043 13.8 0.0 1.6 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit dNK PF01712.19 AIN96879.1 - 0.028 14.3 0.0 0.048 13.5 0.0 1.4 1 0 0 1 1 1 0 Deoxynucleoside kinase SRPRB PF09439.10 AIN96879.1 - 0.04 13.4 0.0 0.069 12.6 0.0 1.4 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit APS_kinase PF01583.20 AIN96879.1 - 0.043 13.7 0.0 0.07 13.0 0.0 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_30 PF13604.6 AIN96879.1 - 0.044 13.5 0.1 0.073 12.8 0.1 1.4 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.6 AIN96879.1 - 0.046 13.8 0.0 0.12 12.4 0.0 1.7 2 0 0 2 2 1 0 AAA domain AAA_29 PF13555.6 AIN96879.1 - 0.058 13.1 0.0 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain PhoH PF02562.16 AIN96879.1 - 0.063 12.7 0.1 0.12 11.8 0.1 1.4 1 0 0 1 1 1 0 PhoH-like protein Hydin_ADK PF17213.3 AIN96879.1 - 0.068 13.4 0.7 0.068 13.4 0.7 1.5 2 0 0 2 2 1 0 Hydin Adenylate kinase-like domain AAA_24 PF13479.6 AIN96879.1 - 0.096 12.4 0.0 0.14 11.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 AIN96879.1 - 0.1 12.0 0.0 0.17 11.3 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Cytidylate_kin PF02224.18 AIN96879.1 - 0.1 12.3 0.2 0.2 11.4 0.2 1.5 1 0 0 1 1 1 0 Cytidylate kinase Sigma54_activat PF00158.26 AIN96879.1 - 0.1 12.3 0.0 0.17 11.6 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain IstB_IS21 PF01695.17 AIN96879.1 - 0.11 12.2 0.0 0.21 11.3 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein Thymidylate_kin PF02223.17 AIN96879.1 - 0.12 12.1 0.0 12 5.6 0.0 2.2 2 0 0 2 2 2 0 Thymidylate kinase PduV-EutP PF10662.9 AIN96879.1 - 0.12 12.1 0.0 0.25 11.1 0.0 1.5 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation NB-ARC PF00931.22 AIN96879.1 - 0.12 11.5 0.0 0.2 10.8 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain CoaE PF01121.20 AIN96879.1 - 0.14 11.8 1.1 0.21 11.3 0.2 1.7 2 0 0 2 2 2 0 Dephospho-CoA kinase ABC_tran PF00005.27 AIN96879.1 - 0.16 12.5 0.0 0.3 11.6 0.0 1.4 1 0 0 1 1 1 0 ABC transporter PrmA PF06325.13 AIN96880.1 - 2.2e-05 24.0 0.3 3.3e-05 23.4 0.3 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 AIN96880.1 - 0.0083 15.7 0.0 0.015 14.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.6 AIN96880.1 - 0.021 15.5 0.1 0.06 14.1 0.1 1.8 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_9 PF08003.11 AIN96880.1 - 0.025 13.5 0.0 0.037 13.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) Met_10 PF02475.16 AIN96880.1 - 0.07 12.9 0.0 0.098 12.4 0.0 1.2 1 0 0 1 1 1 0 Met-10+ like-protein Methyltransf_11 PF08241.12 AIN96880.1 - 0.085 13.5 0.0 0.2 12.3 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain CMAS PF02353.20 AIN96880.1 - 0.088 12.1 0.1 0.17 11.1 0.1 1.5 1 1 0 1 1 1 0 Mycolic acid cyclopropane synthetase Cons_hypoth95 PF03602.15 AIN96880.1 - 0.092 12.4 0.0 0.15 11.7 0.0 1.2 1 0 0 1 1 1 0 Conserved hypothetical protein 95 PCMT PF01135.19 AIN96880.1 - 0.12 12.1 0.1 0.17 11.6 0.1 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) 2OG-FeII_Oxy_3 PF13640.6 AIN96881.1 - 1.6e-11 44.9 0.0 3.8e-11 43.7 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily PhyH PF05721.13 AIN96881.1 - 0.00017 21.9 0.0 0.00032 21.0 0.0 1.4 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Pox_C4_C10 PF03336.13 AIN96881.1 - 0.0062 15.7 0.0 0.23 10.5 0.0 2.3 1 1 0 1 1 1 1 Poxvirus C4/C10 protein TPR_6 PF13174.6 AIN96881.1 - 0.041 14.5 0.2 0.13 13.0 0.2 1.9 1 0 0 1 1 1 0 Tetratricopeptide repeat 2OG-FeII_Oxy PF03171.20 AIN96881.1 - 0.099 13.1 0.0 0.18 12.3 0.0 1.4 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily DEAD PF00270.29 AIN96882.1 - 1.1e-17 64.4 0.0 4.1e-15 56.0 0.0 2.3 1 1 1 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.31 AIN96882.1 - 1.5e-13 51.1 0.0 1.1e-12 48.3 0.0 2.4 2 1 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 AIN96882.1 - 0.03 14.3 0.0 0.065 13.2 0.0 1.6 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit DUF4770 PF15994.5 AIN96882.1 - 0.12 12.6 0.2 2.4 8.4 0.1 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4770) AAA PF00004.29 AIN96883.1 - 4.9e-45 153.2 0.0 2.3e-44 151.0 0.0 2.2 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 AIN96883.1 - 1.1e-06 28.5 0.0 2.7e-06 27.2 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain Vps4_C PF09336.10 AIN96883.1 - 4.6e-05 23.3 0.0 0.00012 22.0 0.0 1.7 1 0 0 1 1 1 1 Vps4 C terminal oligomerisation domain AAA_16 PF13191.6 AIN96883.1 - 0.00012 22.5 0.1 0.0065 16.9 0.0 3.0 2 1 1 3 3 3 1 AAA ATPase domain AAA_2 PF07724.14 AIN96883.1 - 0.00013 22.1 0.0 0.00037 20.6 0.0 1.8 2 0 0 2 2 1 1 AAA domain (Cdc48 subfamily) AAA_lid_3 PF17862.1 AIN96883.1 - 0.00043 20.0 0.3 0.23 11.3 0.0 3.0 3 0 0 3 3 3 1 AAA+ lid domain AAA_33 PF13671.6 AIN96883.1 - 0.0017 18.5 0.0 0.0039 17.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.14 AIN96883.1 - 0.0021 18.1 0.0 0.0087 16.1 0.0 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_14 PF13173.6 AIN96883.1 - 0.0054 16.8 0.0 0.0098 15.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 AIN96883.1 - 0.0055 17.1 0.0 0.011 16.1 0.0 1.5 1 0 0 1 1 1 1 RNA helicase IstB_IS21 PF01695.17 AIN96883.1 - 0.0064 16.2 0.0 0.014 15.1 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein Parvo_NS1 PF01057.17 AIN96883.1 - 0.0098 15.0 0.0 0.016 14.3 0.0 1.2 1 0 0 1 1 1 1 Parvovirus non-structural protein NS1 TIP49 PF06068.13 AIN96883.1 - 0.015 14.5 0.0 0.027 13.7 0.0 1.3 1 0 0 1 1 1 0 TIP49 P-loop domain AAA_7 PF12775.7 AIN96883.1 - 0.018 14.5 0.0 0.034 13.6 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region Mg_chelatase PF01078.21 AIN96883.1 - 0.021 14.2 0.1 0.042 13.2 0.1 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_22 PF13401.6 AIN96883.1 - 0.027 14.7 0.1 0.12 12.7 0.1 2.1 2 1 0 2 2 1 0 AAA domain TsaE PF02367.17 AIN96883.1 - 0.044 13.8 0.0 0.088 12.8 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_28 PF13521.6 AIN96883.1 - 0.053 13.8 0.0 0.16 12.2 0.0 1.9 1 0 0 1 1 1 0 AAA domain ATPase PF06745.13 AIN96883.1 - 0.057 12.8 0.0 0.11 11.8 0.0 1.4 1 0 0 1 1 1 0 KaiC PhoH PF02562.16 AIN96883.1 - 0.06 12.8 0.0 0.14 11.6 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein ABC_tran PF00005.27 AIN96883.1 - 0.079 13.5 0.0 0.15 12.5 0.0 1.4 1 0 0 1 1 1 0 ABC transporter AAA_18 PF13238.6 AIN96883.1 - 0.12 12.9 0.0 0.24 11.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.6 AIN96883.1 - 0.2 12.1 0.0 0.62 10.5 0.0 1.8 2 0 0 2 2 1 0 AAA domain Kelch_4 PF13418.6 AIN96885.1 - 1.4e-33 114.7 0.1 2.6e-12 46.5 0.0 6.5 5 1 1 6 6 6 6 Galactose oxidase, central domain Kelch_5 PF13854.6 AIN96885.1 - 1.5e-25 88.6 3.1 0.001 19.0 0.0 6.5 6 0 0 6 6 6 6 Kelch motif Kelch_3 PF13415.6 AIN96885.1 - 7.8e-24 83.4 2.4 0.00015 21.9 0.0 6.9 6 1 0 6 6 6 5 Galactose oxidase, central domain DUF4110 PF13422.6 AIN96885.1 - 1e-21 76.8 7.8 1e-21 76.8 7.8 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4110) Kelch_6 PF13964.6 AIN96885.1 - 9.8e-19 66.9 6.6 4.7e-05 23.5 0.0 6.6 5 1 1 6 6 6 6 Kelch motif Kelch_1 PF01344.25 AIN96885.1 - 1.3e-18 66.3 0.8 0.0011 18.5 0.0 6.2 6 0 0 6 6 6 4 Kelch motif Kelch_2 PF07646.15 AIN96885.1 - 2.1e-10 40.2 6.8 0.084 12.9 0.1 6.3 6 0 0 6 6 6 2 Kelch motif Cytochrom_NNT PF03264.14 AIN96885.1 - 0.013 15.2 1.5 0.032 14.0 1.5 1.6 1 0 0 1 1 1 0 NapC/NirT cytochrome c family, N-terminal region MORN PF02493.20 AIN96887.1 - 3.6e-13 48.6 9.5 1.6e-07 30.8 0.9 4.8 4 0 0 4 4 4 2 MORN repeat Peptidase_U4 PF03419.13 AIN96887.1 - 0.028 13.7 0.3 0.028 13.7 0.3 2.5 3 0 0 3 3 3 0 Sporulation factor SpoIIGA Ribosomal_S12 PF17487.2 AIN96887.1 - 0.86 10.4 8.5 0.079 13.7 2.5 2.4 2 0 0 2 2 2 0 Ribosomal protein S12 APH PF01636.23 AIN96888.1 - 4.6e-12 46.4 0.0 1.3e-11 44.9 0.0 1.7 1 1 0 1 1 1 1 Phosphotransferase enzyme family WD-3 PF09765.9 AIN96888.1 - 0.14 11.4 0.7 0.31 10.3 0.1 1.7 2 0 0 2 2 2 0 WD-repeat region eIF-1a PF01176.19 AIN96890.1 - 4.2e-13 48.9 0.3 6.2e-13 48.3 0.3 1.3 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 Ribosomal_L17 PF01196.19 AIN96892.1 - 6.3e-12 46.2 0.0 9.4e-12 45.7 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L17 FAD_binding_5 PF00941.21 AIN96893.1 - 0.11 12.3 0.2 3.8 7.2 0.0 2.5 2 0 0 2 2 2 0 FAD binding domain in molybdopterin dehydrogenase Las1 PF04031.13 AIN96895.1 - 8e-33 113.7 0.1 1.4e-32 113.0 0.1 1.4 1 0 0 1 1 1 1 Las1-like DUF5337 PF17272.2 AIN96895.1 - 0.036 13.9 0.4 0.077 12.8 0.4 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5337) DUF3176 PF11374.8 AIN96895.1 - 0.22 11.8 2.7 17 5.7 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3176) Mito_carr PF00153.27 AIN96896.1 - 7.8e-62 205.2 1.2 2.9e-20 72.0 0.0 3.0 2 1 1 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 AIN96896.1 - 0.058 12.5 0.2 18 4.4 0.0 3.2 3 1 1 4 4 4 0 Gammaproteobacterial serine protease Mito_carr PF00153.27 AIN96897.1 - 4.5e-52 173.9 7.0 1.1e-17 63.7 0.4 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein CpcD PF01383.21 AIN96897.1 - 0.22 11.8 1.7 4.3 7.7 0.3 3.1 3 0 0 3 3 3 0 CpcD/allophycocyanin linker domain DSPc PF00782.20 AIN96899.1 - 6.7e-08 32.4 0.0 9.4e-08 31.9 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 AIN96899.1 - 0.00016 21.3 0.0 0.00023 20.8 0.0 1.1 1 0 0 1 1 1 1 Protein-tyrosine phosphatase RuBisCO_large PF00016.20 AIN96899.1 - 0.11 11.7 0.0 0.14 11.3 0.0 1.1 1 0 0 1 1 1 0 Ribulose bisphosphate carboxylase large chain, catalytic domain Radical_SAM_C PF16199.5 AIN96900.1 - 5.3e-21 74.4 0.2 1.8e-20 72.8 0.1 1.9 2 0 0 2 2 2 1 Radical_SAM C-terminal domain Radical_SAM PF04055.21 AIN96900.1 - 1.3e-14 54.9 0.0 5.7e-14 52.8 0.0 2.1 2 0 0 2 2 2 1 Radical SAM superfamily Acetyltransf_1 PF00583.25 AIN96900.1 - 8.5e-08 32.5 0.1 2.3e-07 31.0 0.1 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 AIN96900.1 - 3.9e-05 23.6 0.1 7.5e-05 22.7 0.1 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 AIN96900.1 - 0.013 16.0 0.1 0.027 14.9 0.1 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain DSPc PF00782.20 AIN96901.1 - 5.1e-08 32.8 0.0 6.3e-08 32.5 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 AIN96901.1 - 2e-05 24.3 0.0 2.4e-05 24.0 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Hydrolase_4 PF12146.8 AIN96902.1 - 1.7e-11 43.8 1.7 9.8e-07 28.3 0.3 2.4 2 1 1 3 3 3 2 Serine aminopeptidase, S33 Ank_2 PF12796.7 AIN96902.1 - 7.4e-09 36.1 0.0 6.6e-08 33.0 0.0 2.2 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Abhydrolase_1 PF00561.20 AIN96902.1 - 9.1e-09 35.3 0.3 1.9e-05 24.4 0.2 2.9 3 1 1 4 4 4 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 AIN96902.1 - 5.4e-08 33.7 0.0 1.2e-07 32.6 0.0 1.7 1 0 0 1 1 1 1 Alpha/beta hydrolase family Ank_4 PF13637.6 AIN96902.1 - 1.7e-06 28.4 0.1 6.3e-05 23.5 0.1 3.3 2 1 1 3 3 3 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 AIN96902.1 - 1.7e-06 27.9 0.1 7.2e-05 22.9 0.0 3.5 3 0 0 3 3 3 1 Ankyrin repeat Peptidase_S9 PF00326.21 AIN96902.1 - 4.3e-06 26.4 0.1 0.02 14.4 0.0 2.3 2 0 0 2 2 2 2 Prolyl oligopeptidase family Ank PF00023.30 AIN96902.1 - 6.5e-05 23.2 0.0 0.00042 20.6 0.0 2.5 2 0 0 2 2 2 1 Ankyrin repeat Ank_5 PF13857.6 AIN96902.1 - 0.00011 22.4 0.1 0.0041 17.4 0.0 3.0 2 1 1 3 3 3 2 Ankyrin repeats (many copies) AXE1 PF05448.12 AIN96902.1 - 0.00012 20.9 0.7 0.018 13.8 0.7 2.2 1 1 0 1 1 1 1 Acetyl xylan esterase (AXE1) Peptidase_S15 PF02129.18 AIN96902.1 - 0.0027 17.4 0.0 0.14 11.7 0.0 2.3 2 0 0 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) Say1_Mug180 PF10340.9 AIN96902.1 - 0.13 11.1 0.0 5 5.9 0.0 2.1 2 0 0 2 2 2 0 Steryl acetyl hydrolase HTH_32 PF13565.6 AIN96903.1 - 2.6 8.7 6.6 21 5.8 0.1 4.4 4 0 0 4 4 4 0 Homeodomain-like domain Nas2_N PF18265.1 AIN96904.1 - 1.3e-20 73.0 0.0 2.8e-20 72.0 0.0 1.6 1 0 0 1 1 1 1 Nas2 N_terminal domain PDZ_6 PF17820.1 AIN96904.1 - 0.00045 20.0 0.1 0.0011 18.7 0.1 1.8 1 0 0 1 1 1 1 PDZ domain GRASP55_65 PF04495.14 AIN96904.1 - 0.0012 19.1 0.0 0.002 18.5 0.0 1.4 1 0 0 1 1 1 1 GRASP55/65 PDZ-like domain PDZ_2 PF13180.6 AIN96904.1 - 0.013 15.8 0.0 0.037 14.3 0.0 1.8 1 0 0 1 1 1 0 PDZ domain COMMD1_N PF17221.3 AIN96904.1 - 0.033 14.5 1.7 0.033 14.5 1.7 1.7 2 0 0 2 2 2 0 COMMD1 N-terminal domain DUF4407 PF14362.6 AIN96904.1 - 0.053 12.9 5.7 0.071 12.5 5.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) APH PF01636.23 AIN96904.1 - 1.6 8.6 8.5 1.8 8.4 7.6 1.5 1 1 0 1 1 1 0 Phosphotransferase enzyme family Pkinase PF00069.25 AIN96905.1 - 2.9e-63 213.7 0.0 3.8e-63 213.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 AIN96905.1 - 1e-46 159.4 0.0 1.3e-46 159.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 AIN96905.1 - 0.00037 19.4 0.0 0.00056 18.8 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 AIN96905.1 - 0.081 12.2 0.0 0.25 10.6 0.0 1.7 2 0 0 2 2 2 0 Kinase-like HTH_32 PF13565.6 AIN96906.1 - 2.6 8.7 6.6 21 5.8 0.1 4.4 4 0 0 4 4 4 0 Homeodomain-like domain Met_10 PF02475.16 AIN96907.1 - 1.8e-47 161.6 0.1 3.3e-35 121.7 0.0 2.2 2 0 0 2 2 2 2 Met-10+ like-protein PrmA PF06325.13 AIN96907.1 - 0.0042 16.5 0.0 0.0071 15.8 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) TRM PF02005.16 AIN96907.1 - 0.057 12.6 0.0 0.11 11.7 0.0 1.3 1 0 0 1 1 1 0 N2,N2-dimethylguanosine tRNA methyltransferase FHA PF00498.26 AIN96908.1 - 3.8e-14 52.8 0.0 7.7e-14 51.8 0.0 1.6 1 0 0 1 1 1 1 FHA domain 2OG-FeII_Oxy_2 PF13532.6 AIN96910.1 - 3.9e-62 209.9 0.1 5.4e-62 209.5 0.1 1.2 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily SpvB PF03534.13 AIN96910.1 - 0.036 13.2 0.1 6.1 5.9 0.0 2.1 2 0 0 2 2 2 0 Salmonella virulence plasmid 65kDa B protein TTL PF03133.15 AIN96913.1 - 3.4e-78 262.8 0.0 1.9e-77 260.3 0.0 2.0 1 1 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_ST PF14397.6 AIN96913.1 - 1.8e-05 24.1 0.0 0.018 14.3 0.0 2.2 2 0 0 2 2 2 2 Sugar-transfer associated ATP-grasp ATPgrasp_YheCD PF14398.6 AIN96913.1 - 3.4e-05 23.2 0.0 0.026 13.8 0.0 2.4 2 0 0 2 2 2 2 YheC/D like ATP-grasp ATP-grasp_3 PF02655.14 AIN96913.1 - 0.08 13.0 0.0 3.9 7.5 0.0 2.5 2 0 0 2 2 2 0 ATP-grasp domain XRN_N PF03159.18 AIN96914.1 - 8e-21 74.6 8.7 5.5e-20 71.8 0.0 4.0 4 1 0 4 4 4 2 XRN 5'-3' exonuclease N-terminus NAM-associated PF14303.6 AIN96916.1 - 0.078 13.7 1.8 0.17 12.6 1.8 1.6 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain Pyridoxal_deC PF00282.19 AIN96917.1 - 1.2e-16 60.4 0.6 4.8e-12 45.3 0.0 2.5 3 0 0 3 3 3 2 Pyridoxal-dependent decarboxylase conserved domain B277 PF17623.2 AIN96918.1 - 0.23 10.5 0.4 0.35 9.9 0.4 1.2 1 0 0 1 1 1 0 Domain of unknown function DUF4220 PF13968.6 AIN96919.1 - 0.054 12.9 1.6 0.075 12.4 1.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4220) Ribosomal_L21e PF01157.18 AIN96920.1 - 1.4e-40 137.2 3.1 2.1e-40 136.7 3.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L21e Amastin PF07344.11 AIN96921.1 - 0.058 13.2 14.1 0.068 13.0 13.5 1.4 1 1 0 1 1 1 0 Amastin surface glycoprotein Fucokinase PF07959.12 AIN96922.1 - 1.1e-13 50.9 0.0 5.5e-13 48.6 0.0 2.1 1 1 0 1 1 1 1 L-fucokinase GHMP_kinases_N PF00288.26 AIN96922.1 - 2.2e-05 24.6 1.8 0.00024 21.3 0.0 2.9 2 0 0 2 2 2 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 AIN96922.1 - 0.00036 20.8 0.0 0.0012 19.1 0.0 2.0 1 0 0 1 1 1 1 GHMP kinases C terminal Amastin PF07344.11 AIN96924.1 - 6.9e-06 26.0 10.1 1.2e-05 25.2 10.0 1.5 1 1 0 1 1 1 1 Amastin surface glycoprotein LssY_C PF14067.6 AIN96924.1 - 0.23 11.0 0.0 0.98 8.9 0.0 1.8 2 0 0 2 2 2 0 LssY C-terminus FtsL PF04999.13 AIN96924.1 - 2.4 8.2 4.6 3.4 7.7 0.3 2.5 3 0 0 3 3 3 0 Cell division protein FtsL Rep_3 PF01051.21 AIN96926.1 - 0.058 13.2 0.2 0.09 12.6 0.2 1.2 1 0 0 1 1 1 0 Initiator Replication protein DHO_dh PF01180.21 AIN96927.1 - 8.8e-70 235.2 0.0 1e-69 235.0 0.0 1.0 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase FMN_dh PF01070.18 AIN96927.1 - 0.0021 17.2 0.6 0.0073 15.4 0.1 1.9 2 0 0 2 2 2 1 FMN-dependent dehydrogenase PcrB PF01884.17 AIN96927.1 - 0.17 11.3 0.0 0.26 10.7 0.0 1.3 1 0 0 1 1 1 0 PcrB family OTCace_N PF02729.21 AIN96928.1 - 7.5e-39 133.1 0.3 1.3e-38 132.3 0.3 1.4 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain OTCace PF00185.24 AIN96928.1 - 1.3e-31 109.8 0.1 6.3e-31 107.6 0.0 1.8 2 0 0 2 2 2 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain OMPdecase PF00215.24 AIN96929.1 - 1.8e-36 125.8 0.0 2.6e-36 125.3 0.0 1.2 1 0 0 1 1 1 1 Orotidine 5'-phosphate decarboxylase / HUMPS family Pribosyltran PF00156.27 AIN96929.1 - 1e-18 67.4 0.2 3.2e-18 65.7 0.2 1.8 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.6 AIN96929.1 - 0.00031 20.3 0.0 0.00066 19.2 0.0 1.5 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase PRTase_2 PF15609.6 AIN96929.1 - 0.0008 19.0 0.0 0.0018 17.8 0.0 1.6 1 0 0 1 1 1 1 Phosphoribosyl transferase DUF3933 PF13069.6 AIN96929.1 - 0.021 14.6 0.1 12 5.9 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3933) Phage_Coat_Gp8 PF05371.12 AIN96929.1 - 2.3 8.1 4.9 0.58 10.0 1.1 2.1 2 0 0 2 2 2 0 Phage major coat protein, Gp8 AAA_18 PF13238.6 AIN96930.1 - 0.0007 20.1 0.0 0.0031 18.0 0.0 2.1 2 0 0 2 2 2 1 AAA domain PRK PF00485.18 AIN96930.1 - 0.01 15.6 0.0 0.13 12.0 0.0 2.1 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family AAA_33 PF13671.6 AIN96930.1 - 0.019 15.1 0.0 0.044 13.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain Cytidylate_kin PF02224.18 AIN96930.1 - 0.16 11.6 0.0 0.31 10.7 0.0 1.4 1 0 0 1 1 1 0 Cytidylate kinase Amidohydro_1 PF01979.20 AIN96931.1 - 5.7e-10 39.0 1.4 7.6e-10 38.6 1.4 1.2 1 0 0 1 1 1 1 Amidohydrolase family Usp PF00582.26 AIN96931.1 - 0.13 12.7 0.4 0.35 11.4 0.4 1.7 1 0 0 1 1 1 0 Universal stress protein family CPSase_L_D2 PF02786.17 AIN96932.1 - 3.8e-101 337.0 0.3 1e-76 257.1 0.2 2.3 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_sm_chain PF00988.22 AIN96932.1 - 8.7e-46 154.9 0.0 2.4e-45 153.5 0.0 1.8 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain GATase PF00117.28 AIN96932.1 - 3.1e-40 138.0 0.0 7.9e-40 136.7 0.0 1.8 1 0 0 1 1 1 1 Glutamine amidotransferase class-I CPSase_L_D3 PF02787.19 AIN96932.1 - 1.4e-29 102.9 0.1 3.8e-29 101.5 0.0 1.8 2 0 0 2 2 2 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain ATP-grasp PF02222.22 AIN96932.1 - 2.9e-20 72.6 0.1 6e-11 42.2 0.0 2.4 2 0 0 2 2 2 2 ATP-grasp domain Arginosuc_synth PF00764.19 AIN96932.1 - 1.4e-13 50.9 0.0 3.4e-13 49.7 0.0 1.6 1 0 0 1 1 1 1 Arginosuccinate synthase Dala_Dala_lig_C PF07478.13 AIN96932.1 - 1.6e-11 44.2 0.5 3.5e-05 23.4 0.0 2.4 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus ATPgrasp_Ter PF15632.6 AIN96932.1 - 3.5e-10 39.7 0.0 0.00011 21.9 0.0 2.7 2 1 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon MGS PF02142.22 AIN96932.1 - 2.8e-07 30.6 0.0 1.4e-06 28.4 0.0 2.3 2 0 0 2 2 1 1 MGS-like domain Peptidase_C26 PF07722.13 AIN96932.1 - 3.8e-07 30.1 0.4 2.2e-05 24.3 0.4 2.6 1 1 0 1 1 1 1 Peptidase C26 ATP-grasp_3 PF02655.14 AIN96932.1 - 0.00012 22.1 0.2 0.0042 17.1 0.0 2.6 2 1 0 2 2 2 1 ATP-grasp domain DJ-1_PfpI PF01965.24 AIN96932.1 - 0.00074 19.4 0.1 0.0084 15.9 0.0 2.6 3 0 0 3 3 3 1 DJ-1/PfpI family TrkA_N PF02254.18 AIN96932.1 - 0.0087 16.3 0.0 0.062 13.6 0.0 2.4 2 0 0 2 2 2 1 TrkA-N domain GSH-S_ATP PF02955.16 AIN96932.1 - 0.16 11.4 0.0 0.39 10.1 0.0 1.6 1 0 0 1 1 1 0 Prokaryotic glutathione synthetase, ATP-grasp domain Epimerase_2 PF02350.19 AIN96933.1 - 0.15 10.8 0.0 0.28 10.0 0.0 1.3 1 0 0 1 1 1 0 UDP-N-acetylglucosamine 2-epimerase TP6A_N PF04406.14 AIN96934.1 - 1.8e-10 40.6 0.6 3.6e-10 39.7 0.6 1.5 1 0 0 1 1 1 1 Type IIB DNA topoisomerase DUF2399 PF09664.10 AIN96934.1 - 0.12 12.3 0.5 0.21 11.5 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function C-terminus (DUF2399) RRM_1 PF00076.22 AIN96935.1 - 1.8e-12 46.9 0.0 3.2e-12 46.1 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Pro_isomerase PF00160.21 AIN96935.1 - 5.5e-06 26.7 0.0 0.09 13.0 0.0 2.3 2 0 0 2 2 2 2 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD zf-rbx1 PF12678.7 AIN96936.1 - 3.2e-17 62.5 12.3 4.4e-17 62.1 12.3 1.2 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 AIN96936.1 - 1.1e-14 54.2 7.0 1.5e-14 53.8 7.0 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_2 PF13639.6 AIN96936.1 - 2.4e-10 40.6 13.8 5.5e-09 36.2 10.8 2.2 2 0 0 2 2 2 1 Ring finger domain Prok-RING_4 PF14447.6 AIN96936.1 - 1.1e-06 28.3 12.3 2.3e-05 24.2 9.1 2.2 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 AIN96936.1 - 1.2e-06 28.3 13.0 5e-06 26.4 8.8 2.2 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 AIN96936.1 - 1.5e-05 24.9 12.2 0.00022 21.2 10.0 2.8 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 AIN96936.1 - 2.5e-05 24.1 13.0 0.00015 21.5 7.6 2.2 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.6 AIN96936.1 - 3.1e-05 23.8 5.4 3.1e-05 23.8 5.4 1.7 1 1 1 2 2 2 1 zf-RING of BARD1-type protein zf-C3HC4_2 PF13923.6 AIN96936.1 - 0.0001 22.1 16.0 0.00097 18.9 11.4 2.4 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 AIN96936.1 - 0.00073 19.1 9.7 0.00073 19.1 9.7 1.8 1 1 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-C3HC4 PF00097.25 AIN96936.1 - 0.00078 19.3 12.5 0.0041 17.0 12.5 2.1 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) FANCL_C PF11793.8 AIN96936.1 - 0.0023 18.1 13.1 0.032 14.4 3.8 3.2 1 1 2 3 3 3 1 FANCL C-terminal domain Rtf2 PF04641.12 AIN96936.1 - 0.0062 15.9 0.2 0.0062 15.9 0.2 1.9 1 1 1 2 2 2 1 Rtf2 RING-finger zf-RING_4 PF14570.6 AIN96936.1 - 0.096 12.5 9.6 2.6 7.9 6.9 2.6 2 1 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-RING_11 PF17123.5 AIN96936.1 - 0.31 10.8 14.1 8 6.3 14.1 2.4 1 1 0 1 1 1 0 RING-like zinc finger zf-Di19 PF05605.12 AIN96936.1 - 0.42 10.9 9.7 1.1 9.6 4.6 2.3 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding Rad50_zn_hook PF04423.14 AIN96936.1 - 0.56 10.1 4.2 13 5.7 0.3 2.7 2 1 0 2 2 2 0 Rad50 zinc hook motif DUF1272 PF06906.11 AIN96936.1 - 0.75 9.9 11.0 56 3.9 11.0 2.9 1 1 0 1 1 1 0 Protein of unknown function (DUF1272) zf-Nse PF11789.8 AIN96936.1 - 0.8 9.6 7.4 3.8 7.4 7.4 2.1 1 1 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit tRNA-synt_1g PF09334.11 AIN96936.1 - 0.93 8.2 3.1 1.7 7.3 0.5 1.9 1 1 1 2 2 2 0 tRNA synthetases class I (M) zf-C3HC4_4 PF15227.6 AIN96936.1 - 1.4 9.1 13.3 34 4.7 2.0 3.3 1 1 2 3 3 3 0 zinc finger of C3HC4-type, RING TerY_C PF15616.6 AIN96936.1 - 3.9 7.6 10.0 64 3.7 10.0 2.0 1 1 0 1 1 1 0 TerY-C metal binding domain Zn-C2H2_12 PF18112.1 AIN96936.1 - 4.5 7.8 10.4 18 5.9 0.1 3.4 3 1 0 3 3 3 0 Autophagy receptor zinc finger-C2H2 domain zf-C3H2C3 PF17122.5 AIN96936.1 - 6.6 6.9 15.3 0.96 9.5 8.9 2.3 1 1 0 2 2 2 0 Zinc-finger HMMR_N PF15905.5 AIN96937.1 - 0.00051 19.6 28.8 0.00051 19.6 28.8 4.3 2 2 2 4 4 4 1 Hyaluronan mediated motility receptor N-terminal LpxK PF02606.14 AIN96938.1 - 0.0089 15.2 0.0 0.015 14.4 0.0 1.3 1 0 0 1 1 1 1 Tetraacyldisaccharide-1-P 4'-kinase DUF1738 PF08401.11 AIN96938.1 - 0.069 13.3 0.0 2.5 8.2 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1738) Exo_endo_phos PF03372.23 AIN96939.1 - 7.4e-16 58.4 0.0 1.4e-15 57.4 0.0 1.5 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family eIF2A PF08662.11 AIN96940.1 - 4.7e-39 134.3 0.0 7.9e-31 107.4 0.0 3.2 2 1 1 3 3 3 3 Eukaryotic translation initiation factor eIF2A LysM PF01476.20 AIN96941.1 - 8.9e-06 25.7 0.0 0.1 12.7 0.0 2.3 2 0 0 2 2 2 2 LysM domain Spc29 PF17082.5 AIN96942.1 - 0.0069 16.3 0.2 0.016 15.1 0.2 1.5 1 0 0 1 1 1 1 Spindle Pole Component 29 LRR_6 PF13516.6 AIN96943.1 - 1e-09 37.7 12.6 0.83 9.9 0.1 6.7 6 0 0 6 6 6 5 Leucine Rich repeat LRR_4 PF12799.7 AIN96943.1 - 1.5e-06 28.4 3.1 0.031 14.7 0.0 4.2 4 0 0 4 4 4 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 AIN96943.1 - 6.5e-05 22.9 1.6 16 6.5 0.0 5.6 5 0 0 5 5 5 1 Leucine Rich Repeat LRR_8 PF13855.6 AIN96943.1 - 0.06 13.1 10.4 2.9 7.7 0.4 4.5 3 1 1 4 4 4 0 Leucine rich repeat UCH PF00443.29 AIN96944.1 - 6.8e-35 120.8 0.0 1.2e-34 119.9 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 AIN96944.1 - 1.1e-17 64.6 0.0 1.5e-15 57.6 0.0 2.5 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase TetR_C_27 PF17935.1 AIN96944.1 - 0.013 15.6 0.3 6.1 6.9 0.0 2.7 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain GDH_N PF12466.8 AIN96944.1 - 1.3 9.3 3.9 5.8 7.2 0.0 3.9 4 0 0 4 4 4 0 Glutamate dehydrogenase N terminal TAL_FSA PF00923.19 AIN96947.1 - 2e-96 322.7 0.0 2.3e-96 322.5 0.0 1.0 1 0 0 1 1 1 1 Transaldolase/Fructose-6-phosphate aldolase FixO PF02433.15 AIN96947.1 - 0.14 11.6 0.0 0.23 10.9 0.0 1.3 1 0 0 1 1 1 0 Cytochrome C oxidase, mono-heme subunit/FixO SH3BGR PF04908.15 AIN96948.1 - 0.0087 16.2 0.0 0.02 15.1 0.0 1.5 1 0 0 1 1 1 1 SH3-binding, glutamic acid-rich protein VPS13 PF16908.5 AIN96949.1 - 3.5e-29 102.3 0.0 1.2e-28 100.5 0.0 2.0 1 0 0 1 1 1 1 Vacuolar sorting-associated protein 13, N-terminal VPS13_C PF16909.5 AIN96949.1 - 6.7e-21 74.9 0.2 3.7e-14 52.9 0.0 2.4 2 0 0 2 2 2 2 Vacuolar-sorting-associated 13 protein C-terminal Chorein_N PF12624.7 AIN96949.1 - 6.8e-18 64.9 0.2 2.9e-10 40.3 0.1 2.8 2 0 0 2 2 2 2 N-terminal region of Chorein or VPS13 VPS13_mid_rpt PF16910.5 AIN96949.1 - 2.3e-12 46.8 0.0 4.2e-09 36.2 0.0 3.1 3 0 0 3 3 3 2 Repeating coiled region of VPS13 SHR-BD PF06650.12 AIN96949.1 - 0.0024 17.3 0.0 4.9 6.5 0.0 3.8 4 0 0 4 4 4 1 SHR-binding domain of vacuolar-sorting associated protein 13 TFIIS_C PF01096.18 AIN96949.1 - 0.1 12.5 1.7 0.47 10.3 1.7 2.3 1 0 0 1 1 1 0 Transcription factor S-II (TFIIS) Roughex PF06020.11 AIN96949.1 - 2.3 7.2 6.2 0.18 10.8 0.2 2.1 2 0 0 2 2 2 0 Drosophila roughex protein Glyco_hydro_18 PF00704.28 AIN96950.1 - 2.9e-48 165.2 0.0 3.5e-48 164.9 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Mem_trans PF03547.18 AIN96951.1 - 3.4e-08 32.3 20.1 7.8e-08 31.1 0.1 3.3 3 1 0 3 3 3 2 Membrane transport protein DUF1427 PF07235.11 AIN96951.1 - 0.19 11.7 3.0 7.6 6.6 0.9 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF1427) BILBO1_N PF18281.1 AIN96953.1 - 5.7e-05 23.5 0.2 0.0095 16.3 0.1 2.4 2 0 0 2 2 2 2 BILBO1 N-terminal domain EF-hand_1 PF00036.32 AIN96953.1 - 0.022 14.3 0.0 0.043 13.4 0.0 1.4 1 0 0 1 1 1 0 EF hand Fe-S_biosyn PF01521.20 AIN96954.1 - 7.1e-08 32.6 0.1 5.5e-07 29.8 0.1 2.3 1 1 0 1 1 1 1 Iron-sulphur cluster biosynthesis ALF PF03752.13 AIN96955.1 - 0.48 10.4 2.5 7.8 6.6 0.9 2.6 2 0 0 2 2 2 0 Short repeats of unknown function JAB PF01398.21 AIN96956.1 - 7e-21 74.4 0.0 1.1e-20 73.7 0.0 1.3 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Prok-JAB PF14464.6 AIN96956.1 - 0.0029 17.4 0.0 0.0084 15.9 0.0 1.8 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain REV PF00424.18 AIN96957.1 - 0.036 14.1 0.0 0.19 11.8 0.0 2.0 1 1 1 2 2 2 0 REV protein (anti-repression trans-activator protein) Pkinase PF00069.25 AIN96958.1 - 2e-30 106.1 0.0 1.1e-29 103.6 0.0 1.9 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 AIN96958.1 - 1.6e-23 83.3 0.0 5e-23 81.7 0.0 1.8 2 1 0 2 2 2 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 AIN96958.1 - 1.3e-05 24.2 0.0 2.3e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase zf-ACC PF17848.1 AIN96958.1 - 0.06 13.4 0.1 0.12 12.5 0.1 1.5 1 0 0 1 1 1 0 Acetyl-coA carboxylase zinc finger domain EcKinase PF02958.20 AIN96958.1 - 0.15 11.3 0.0 0.27 10.5 0.0 1.3 1 0 0 1 1 1 0 Ecdysteroid kinase zf-C2H2_4 PF13894.6 AIN96958.1 - 0.38 11.7 2.0 1.1 10.3 2.0 1.9 1 0 0 1 1 1 0 C2H2-type zinc finger Nop52 PF05997.12 AIN96959.1 - 4.5e-33 114.9 0.8 2.5e-27 96.1 0.3 3.4 3 0 0 3 3 3 3 Nucleolar protein,Nop52 EF-hand_6 PF13405.6 AIN96962.1 - 4.6e-15 54.2 1.1 0.00085 19.1 0.0 3.9 4 0 0 4 4 4 3 EF-hand domain EF-hand_1 PF00036.32 AIN96962.1 - 5.9e-15 53.6 0.9 1.4e-05 24.2 0.0 4.0 4 0 0 4 4 4 3 EF hand EF-hand_7 PF13499.6 AIN96962.1 - 4.3e-13 49.5 0.5 7.3e-08 32.8 0.1 3.1 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_8 PF13833.6 AIN96962.1 - 5.1e-09 35.8 2.8 0.0026 17.6 0.1 3.9 3 1 1 4 4 4 3 EF-hand domain pair EF-hand_5 PF13202.6 AIN96962.1 - 1.2e-06 27.7 1.9 0.15 11.6 0.3 3.6 3 1 0 3 3 3 2 EF hand EF-hand_10 PF14788.6 AIN96962.1 - 0.0057 16.5 0.0 0.52 10.2 0.0 3.0 3 0 0 3 3 3 1 EF hand SPARC_Ca_bdg PF10591.9 AIN96962.1 - 0.0088 16.4 0.4 0.062 13.6 0.0 2.1 1 1 1 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_11 PF08976.11 AIN96962.1 - 0.05 14.5 0.1 0.21 12.4 0.0 1.9 2 0 0 2 2 2 0 EF-hand domain Snf7 PF03357.21 AIN96963.1 - 6.6e-23 81.2 15.2 8.2e-23 80.9 15.2 1.2 1 0 0 1 1 1 1 Snf7 Herpes_U44 PF04533.13 AIN96963.1 - 0.076 12.6 2.2 0.22 11.1 0.9 2.0 1 1 0 2 2 2 0 Herpes virus U44 protein DUF3801 PF12687.7 AIN96963.1 - 0.38 10.8 5.8 0.32 11.0 4.6 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3801) SSXT PF05030.12 AIN96963.1 - 0.78 9.4 5.8 2.8 7.6 0.4 2.5 2 0 0 2 2 2 0 SSXT protein (N-terminal region) Dynein_light PF01221.18 AIN96964.1 - 8.8e-25 86.8 0.6 1e-24 86.6 0.6 1.1 1 0 0 1 1 1 1 Dynein light chain type 1 Glycos_transf_1 PF00534.20 AIN96965.1 - 1.2e-27 96.6 0.0 2.1e-27 95.8 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 AIN96965.1 - 3.2e-18 66.5 0.0 6.7e-18 65.4 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 AIN96965.1 - 0.0006 19.9 0.0 0.001 19.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_1_2 PF13524.6 AIN96965.1 - 0.0028 18.0 0.0 0.0069 16.8 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferases group 1 HMG_box_2 PF09011.10 AIN96965.1 - 0.11 13.1 0.0 3.5 8.3 0.0 2.4 2 0 0 2 2 2 0 HMG-box domain Methyltransf_23 PF13489.6 AIN96966.1 - 6.1e-15 55.4 0.0 6e-14 52.2 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 AIN96966.1 - 1.3e-14 54.6 0.0 1.5e-13 51.1 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 AIN96966.1 - 2.8e-11 43.2 0.0 2.1e-10 40.3 0.0 2.0 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.6 AIN96966.1 - 1.1e-10 42.1 0.0 1.1e-07 32.4 0.0 2.7 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_31 PF13847.6 AIN96966.1 - 1.2e-06 28.4 0.0 3.8e-05 23.5 0.0 2.4 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 AIN96966.1 - 4.4e-06 27.3 0.0 0.0011 19.7 0.0 2.7 2 0 0 2 2 2 1 Methyltransferase domain ZapB PF06005.12 AIN96968.1 - 0.02 15.4 1.0 0.02 15.4 1.0 13.4 4 3 4 9 9 9 0 Cell division protein ZapB HALZ PF02183.18 AIN96968.1 - 0.048 13.9 0.8 0.048 13.9 0.8 6.9 9 0 0 9 9 9 0 Homeobox associated leucine zipper DUF2325 PF10087.9 AIN96968.1 - 0.39 10.9 2.6 16 5.7 0.0 4.7 5 0 0 5 5 5 0 Uncharacterized protein conserved in bacteria (DUF2325) DUF4041 PF13250.6 AIN96968.1 - 0.52 10.2 4.7 0.72 9.8 0.1 3.6 4 0 0 4 4 4 0 Domain of unknown function (DUF4041) Hemagglutinin PF00509.18 AIN96968.1 - 1.2 7.4 7.2 0.11 10.9 2.0 1.8 2 0 0 2 2 2 0 Haemagglutinin Pkinase PF00069.25 AIN96969.1 - 2.6e-58 197.5 0.0 5e-34 117.9 0.0 2.8 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 AIN96969.1 - 6.9e-29 100.9 0.0 2e-19 69.9 0.0 3.1 3 0 0 3 3 3 2 Protein tyrosine kinase PNP_UDP_1 PF01048.20 AIN96969.1 - 0.026 13.8 0.0 0.05 12.9 0.0 1.4 1 0 0 1 1 1 0 Phosphorylase superfamily Kdo PF06293.14 AIN96969.1 - 0.041 13.2 0.0 0.081 12.3 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Stealth_CR2 PF11380.8 AIN96970.1 - 2.6e-08 34.0 0.0 5.3e-08 33.0 0.0 1.5 1 0 0 1 1 1 1 Stealth protein CR2, conserved region 2 Stealth_CR2 PF11380.8 AIN96972.1 - 8.4e-17 61.3 0.0 1.2e-08 35.1 0.0 2.4 2 0 0 2 2 2 2 Stealth protein CR2, conserved region 2 Stealth_CR2 PF11380.8 AIN96974.1 - 7.2e-17 61.5 0.0 1.9e-08 34.4 0.0 2.5 2 0 0 2 2 2 2 Stealth protein CR2, conserved region 2 Stealth_CR3 PF17102.5 AIN96974.1 - 2.5e-07 30.5 3.9 1.3e-06 28.2 3.9 2.4 1 0 0 1 1 1 1 Stealth protein CR3, conserved region 3 GCFC PF07842.12 AIN96974.1 - 0.16 11.5 0.1 0.61 9.7 0.0 1.8 2 0 0 2 2 2 0 GC-rich sequence DNA-binding factor-like protein Stealth_CR2 PF11380.8 AIN96975.1 - 2.6e-17 62.9 0.0 5.7e-09 36.1 0.0 2.6 2 0 0 2 2 2 2 Stealth protein CR2, conserved region 2 Stealth_CR3 PF17102.5 AIN96975.1 - 3.9e-12 45.9 0.7 8.8e-12 44.7 0.7 1.7 1 0 0 1 1 1 1 Stealth protein CR3, conserved region 3 Virul_fac_BrkB PF03631.15 AIN96975.1 - 0.0096 15.6 0.8 0.017 14.7 0.8 1.3 1 0 0 1 1 1 1 Virulence factor BrkB Ufm1 PF03671.14 AIN96976.1 - 5.7e-34 116.0 0.1 6.7e-34 115.8 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin fold modifier 1 protein GRA6 PF05084.13 AIN96977.1 - 0.035 14.1 3.2 0.069 13.1 3.2 1.4 1 0 0 1 1 1 0 Granule antigen protein (GRA6) Lge1 PF11488.8 AIN96980.1 - 1.9 8.7 4.3 17 5.7 0.1 2.6 2 0 0 2 2 2 0 Transcriptional regulatory protein LGE1 Polyketide_cyc PF03364.20 AIN96981.1 - 9.8e-12 45.2 0.1 8.5e-11 42.2 0.1 2.1 1 1 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Antimicrobial_8 PF08103.11 AIN96981.1 - 0.55 10.5 2.2 7.9 6.8 0.1 3.1 3 0 0 3 3 3 0 Uperin family tRNA_bind PF01588.20 AIN96983.1 - 1.3e-22 79.7 0.0 2.2e-22 79.0 0.0 1.4 1 0 0 1 1 1 1 Putative tRNA binding domain WW PF00397.26 AIN96984.1 - 5.1e-45 151.2 34.8 2.4e-14 53.1 2.1 5.3 5 0 0 5 5 5 5 WW domain Tfb5 PF06331.12 AIN96985.1 - 4.8e-05 23.2 0.0 0.00013 21.9 0.0 1.6 1 1 0 1 1 1 1 Transcription factor TFIIH complex subunit Tfb5 Ribosomal_L39 PF00832.20 AIN96988.1 - 3.4e-18 65.0 15.4 3.8e-18 64.8 15.4 1.0 1 0 0 1 1 1 1 Ribosomal L39 protein Adap_comp_sub PF00928.21 AIN96989.1 - 2.8e-13 49.8 0.0 4.3e-13 49.2 0.0 1.2 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 AIN96989.1 - 0.00079 19.4 0.0 0.0014 18.5 0.0 1.4 1 0 0 1 1 1 1 Clathrin adaptor complex small chain AAA_25 PF13481.6 AIN96989.1 - 0.1 12.2 0.0 0.22 11.1 0.0 1.5 1 1 0 1 1 1 0 AAA domain RSN1_7TM PF02714.15 AIN96990.1 - 7e-25 87.9 10.1 1.3e-24 87.0 10.1 1.4 1 0 0 1 1 1 1 Calcium-dependent channel, 7TM region, putative phosphate HDPD PF02924.14 AIN96990.1 - 0.074 13.2 0.0 0.2 11.7 0.0 1.8 1 0 0 1 1 1 0 Bacteriophage lambda head decoration protein D Methyltransf_9 PF08003.11 AIN96990.1 - 0.089 11.7 0.1 0.17 10.8 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) Pro_isomerase PF00160.21 AIN96991.1 - 9.3e-31 107.2 0.0 1.4e-30 106.6 0.0 1.3 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD dsrm PF00035.26 AIN96992.1 - 0.0044 17.7 0.1 4.2 8.1 0.0 3.9 4 0 0 4 4 4 1 Double-stranded RNA binding motif Cullin PF00888.22 AIN96993.1 - 1.7e-38 132.7 0.0 1.4e-32 113.1 0.0 4.1 4 1 0 4 4 4 2 Cullin family Cullin_Nedd8 PF10557.9 AIN96993.1 - 1.8e-15 56.7 0.0 3.1e-15 56.0 0.0 1.4 1 0 0 1 1 1 1 Cullin protein neddylation domain QWRF PF04484.12 AIN96995.1 - 0.0074 16.1 1.8 0.0074 16.1 1.8 5.2 6 1 0 7 7 7 1 QWRF family DUF5133 PF17196.4 AIN96995.1 - 0.48 10.7 2.5 7 6.9 1.5 3.3 2 0 0 2 2 2 0 Protein of unknown function (DUF5133) LSM PF01423.22 AIN96996.1 - 7.2e-05 22.4 0.1 0.00039 20.1 0.1 2.0 1 1 0 1 1 1 1 LSM domain FYTT PF07078.11 AIN96996.1 - 0.14 11.4 0.1 0.17 11.2 0.1 1.1 1 0 0 1 1 1 0 Forty-two-three protein Raf1_N PF18578.1 AIN96999.1 - 0.082 13.4 0.5 0.11 12.9 0.5 1.3 1 1 0 1 1 1 0 Rubisco accumulation factor 1 alpha helical domain DAGK_acc PF00609.19 AIN97000.1 - 9.7e-22 78.0 0.0 5.3e-21 75.6 0.0 2.2 1 1 0 1 1 1 1 Diacylglycerol kinase accessory domain DAGK_cat PF00781.24 AIN97000.1 - 7.1e-07 28.9 0.0 2.8e-06 27.0 0.0 1.9 1 1 0 1 1 1 1 Diacylglycerol kinase catalytic domain Nrf1_activ_bdg PF10492.9 AIN97001.1 - 0.086 13.5 4.5 48 4.7 0.0 4.6 4 0 0 4 4 4 0 Nrf1 activator activation site binding domain Cytochrom_C PF00034.21 AIN97002.1 - 3.1e-11 44.3 0.0 3.8e-11 44.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome c Cytochrome_CBB3 PF13442.6 AIN97002.1 - 0.00015 22.0 1.0 0.0011 19.2 1.0 2.0 1 1 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C PF00034.21 AIN97003.1 - 5.8e-11 43.4 0.0 7.2e-11 43.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome c Cytochrome_CBB3 PF13442.6 AIN97003.1 - 0.00015 22.0 1.0 0.0011 19.2 1.0 2.0 1 1 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III LRR_4 PF12799.7 AIN97004.1 - 8.5e-25 86.4 28.8 0.0056 17.1 0.0 12.4 8 3 4 14 14 14 10 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 AIN97004.1 - 9.9e-15 54.1 31.0 3.7e-05 23.4 0.6 9.2 7 2 1 9 9 9 6 Leucine rich repeat LRR_6 PF13516.6 AIN97004.1 - 4.6e-08 32.5 29.3 0.83 9.9 0.1 12.4 13 0 0 13 13 13 5 Leucine Rich repeat LRR_9 PF14580.6 AIN97004.1 - 0.00033 20.2 16.3 0.5 9.9 0.1 6.2 5 2 2 7 7 7 4 Leucine-rich repeat RNA_pol_Rpb1_5 PF04998.17 AIN97006.1 - 4.5e-58 196.8 0.0 1.5e-57 195.0 0.0 1.8 1 1 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.20 AIN97006.1 - 3.2e-49 167.3 0.0 5.7e-49 166.5 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.18 AIN97006.1 - 4.4e-29 101.5 0.0 9.6e-29 100.3 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.17 AIN97006.1 - 3.7e-15 55.8 0.6 1e-14 54.4 0.6 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 RNA_pol_Rpb1_1 PF04997.12 AIN97006.1 - 0.16 11.3 0.5 0.45 9.8 0.0 2.0 3 0 0 3 3 3 0 RNA polymerase Rpb1, domain 1 Amidase PF01425.21 AIN97007.1 - 1.2e-59 202.5 0.0 8.8e-59 199.6 0.0 1.9 1 1 0 1 1 1 1 Amidase LSM PF01423.22 AIN97008.1 - 3.2e-05 23.5 0.0 4.3e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 LSM domain Arf PF00025.21 AIN97009.1 - 1.2e-48 164.8 0.0 1.4e-48 164.6 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 AIN97009.1 - 2e-10 40.9 0.0 2.8e-10 40.4 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 AIN97009.1 - 3.8e-10 39.5 0.0 4.9e-10 39.1 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.27 AIN97009.1 - 9e-10 38.4 0.5 1.3e-08 34.6 0.2 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain Ras PF00071.22 AIN97009.1 - 3.3e-09 36.5 0.0 3.8e-09 36.3 0.0 1.1 1 0 0 1 1 1 1 Ras family G-alpha PF00503.20 AIN97009.1 - 8.9e-09 35.0 2.1 7e-05 22.1 0.3 2.7 1 1 1 2 2 2 2 G-protein alpha subunit MMR_HSR1 PF01926.23 AIN97009.1 - 4.2e-08 33.3 0.0 5.7e-08 32.8 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 AIN97009.1 - 6.5e-07 28.9 0.1 8.2e-07 28.6 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_22 PF13401.6 AIN97009.1 - 0.00011 22.5 0.1 0.0062 16.8 0.1 2.1 1 1 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 AIN97009.1 - 0.00027 20.9 0.0 0.28 11.1 0.0 2.1 2 0 0 2 2 2 2 RsgA GTPase FeoB_N PF02421.18 AIN97009.1 - 0.00036 20.1 0.1 0.00065 19.3 0.1 1.5 1 1 0 1 1 1 1 Ferrous iron transport protein B cobW PF02492.19 AIN97009.1 - 0.012 15.2 0.0 1.8 8.2 0.0 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_18 PF13238.6 AIN97009.1 - 0.018 15.6 0.0 0.03 14.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain Septin PF00735.18 AIN97009.1 - 0.12 11.6 0.0 0.2 10.9 0.0 1.4 1 0 0 1 1 1 0 Septin OTU PF02338.19 AIN97010.1 - 3.7e-14 53.3 0.0 6.8e-14 52.5 0.0 1.4 1 0 0 1 1 1 1 OTU-like cysteine protease EMG1 PF03587.14 AIN97011.1 - 2.1e-57 194.0 0.0 3.6e-57 193.2 0.0 1.4 1 1 0 1 1 1 1 EMG1/NEP1 methyltransferase HTH_18 PF12833.7 AIN97011.1 - 0.02 15.2 0.2 8.7 6.7 0.0 2.4 2 0 0 2 2 2 0 Helix-turn-helix domain TRAPP PF04051.16 AIN97012.1 - 1.9e-23 82.8 0.0 2.3e-23 82.5 0.0 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component IQ PF00612.27 AIN97013.1 - 0.069 13.0 0.4 0.22 11.4 0.4 1.9 1 0 0 1 1 1 0 IQ calmodulin-binding motif YojJ PF10372.9 AIN97013.1 - 0.11 12.6 0.6 0.36 11.0 0.6 2.0 1 0 0 1 1 1 0 Bacterial membrane-spanning protein N-terminus DUF4681 PF15732.5 AIN97013.1 - 0.34 11.2 5.1 0.76 10.1 4.1 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF4681) DUF2730 PF10805.8 AIN97013.1 - 7.1 6.8 9.5 2.2 8.4 0.9 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF2730) LCIB_C_CA PF18599.1 AIN97013.1 - 7.4 5.8 7.3 1.2 8.4 0.6 2.4 1 1 0 2 2 2 0 Limiting CO2-inducible proteins B/C beta carbonyic anhydrases CLN3 PF02487.17 AIN97014.1 - 0.59 9.1 3.0 0.84 8.6 3.0 1.2 1 0 0 1 1 1 0 CLN3 protein Flagellar_rod PF05149.12 AIN97015.1 - 3.4e-105 351.6 28.2 3.4e-105 351.6 28.2 2.0 2 0 0 2 2 2 1 Paraflagellar rod protein ING PF12998.7 AIN97015.1 - 5.6 7.6 19.0 0.078 13.6 3.0 3.6 3 0 0 3 3 3 0 Inhibitor of growth proteins N-terminal histone-binding UPF0225 PF17775.1 AIN97015.1 - 5.6 7.8 9.5 7.4 7.4 1.3 3.4 2 1 0 2 2 2 0 UPF0225 domain DUF3552 PF12072.8 AIN97017.1 - 0.0033 16.9 13.9 0.026 13.9 6.4 2.2 2 1 0 2 2 2 2 Domain of unknown function (DUF3552) AP4E_app_platf PF14807.6 AIN97017.1 - 0.036 14.4 0.4 0.062 13.7 0.4 1.6 1 0 0 1 1 1 0 Adaptin AP4 complex epsilon appendage platform YabA PF06156.13 AIN97017.1 - 0.064 13.9 4.9 1.5 9.5 0.9 2.3 2 0 0 2 2 2 0 Initiation control protein YabA V-SNARE_C PF12352.8 AIN97017.1 - 0.081 13.2 0.9 1.4 9.3 0.5 2.7 2 0 0 2 2 2 0 Snare region anchored in the vesicle membrane C-terminus Laminin_II PF06009.12 AIN97017.1 - 0.15 12.1 10.6 0.21 11.6 6.6 2.3 2 1 0 2 2 2 0 Laminin Domain II Fez1 PF06818.15 AIN97017.1 - 0.21 12.0 12.8 0.14 12.6 8.2 2.0 1 1 1 2 2 2 0 Fez1 KxDL PF10241.9 AIN97017.1 - 0.35 11.2 6.7 7 7.0 2.9 2.6 2 1 0 2 2 2 0 Uncharacterized conserved protein COG2 PF06148.11 AIN97017.1 - 0.77 9.8 10.1 0.13 12.4 3.3 2.3 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Spc7 PF08317.11 AIN97017.1 - 0.91 8.3 14.2 0.21 10.5 8.1 2.0 1 1 1 2 2 2 0 Spc7 kinetochore protein DUF1993 PF09351.10 AIN97017.1 - 1.4 9.1 7.4 5.2 7.2 3.2 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF1993) ApoLp-III PF07464.11 AIN97017.1 - 1.4 9.0 12.5 6.3 6.9 8.0 2.6 2 2 0 2 2 2 0 Apolipophorin-III precursor (apoLp-III) TMF_DNA_bd PF12329.8 AIN97017.1 - 1.4 8.9 13.2 7.4 6.7 11.4 2.5 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding DUF2703 PF10865.8 AIN97017.1 - 1.6 8.9 6.6 10 6.3 3.9 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF2703) BORCS7 PF16088.5 AIN97017.1 - 2.4 8.4 10.5 4.4 7.6 4.3 2.2 2 0 0 2 2 2 0 BLOC-1-related complex sub-unit 7 MCPsignal PF00015.21 AIN97017.1 - 3.6 7.4 11.3 7.6 6.3 4.1 2.1 1 1 1 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain MukF_M PF17192.4 AIN97017.1 - 5.5 6.7 11.8 1 9.1 5.6 2.4 2 1 0 2 2 2 0 MukF middle domain WXG100 PF06013.12 AIN97017.1 - 5.7 7.2 9.9 19 5.6 3.2 3.2 2 2 1 3 3 3 0 Proteins of 100 residues with WXG Fib_alpha PF08702.10 AIN97017.1 - 6.7 6.9 8.8 3.9 7.7 2.3 2.3 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family Kinesin PF00225.23 AIN97018.1 - 1.8e-77 260.5 0.0 3.4e-77 259.6 0.0 1.4 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 AIN97018.1 - 1.2e-20 73.9 0.0 2.8e-20 72.8 0.0 1.6 1 0 0 1 1 1 1 Microtubule binding Spc7 PF08317.11 AIN97018.1 - 0.0032 16.4 31.1 0.016 14.2 13.0 2.9 1 1 2 3 3 3 2 Spc7 kinetochore protein Filament PF00038.21 AIN97018.1 - 0.0036 16.9 16.5 0.0036 16.9 16.5 2.3 1 1 1 2 2 2 1 Intermediate filament protein Baculo_PEP_C PF04513.12 AIN97018.1 - 0.0049 16.9 13.7 0.0056 16.7 6.0 3.2 2 1 1 3 3 3 1 Baculovirus polyhedron envelope protein, PEP, C terminus PhoH PF02562.16 AIN97018.1 - 0.035 13.6 0.0 0.079 12.4 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein CENP-F_leu_zip PF10473.9 AIN97018.1 - 0.33 11.0 38.6 0.11 12.5 18.9 3.2 1 1 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Fez1 PF06818.15 AIN97018.1 - 0.76 10.2 27.9 1.3 9.5 13.4 2.8 1 1 0 2 2 2 0 Fez1 FAM76 PF16046.5 AIN97018.1 - 0.87 8.9 17.9 0.59 9.4 6.8 2.8 1 1 1 3 3 3 0 FAM76 protein Enkurin PF13864.6 AIN97018.1 - 1.1 9.8 15.0 0.12 12.8 6.4 3.2 1 1 2 3 3 3 0 Calmodulin-binding DUF724 PF05266.14 AIN97018.1 - 2.2 8.1 21.5 0.69 9.7 10.5 2.9 1 1 1 3 3 3 0 Protein of unknown function (DUF724) MCC-bdg_PDZ PF10506.9 AIN97018.1 - 2.2 8.3 14.0 2.6 8.1 2.5 4.0 3 1 1 4 4 4 0 PDZ domain of MCC-2 bdg protein for Usher syndrome DUF1664 PF07889.12 AIN97018.1 - 2.2 8.3 13.7 2.4 8.2 5.2 3.6 1 1 2 4 4 4 0 Protein of unknown function (DUF1664) Bacillus_HBL PF05791.11 AIN97018.1 - 2.6 7.8 6.9 18 5.1 3.6 2.5 1 1 1 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) Fib_alpha PF08702.10 AIN97018.1 - 2.8 8.1 11.7 2.6 8.2 0.2 3.4 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family ABC_tran_CTD PF16326.5 AIN97018.1 - 3.9 7.8 49.3 0.73 10.1 2.3 5.4 4 1 1 5 5 5 0 ABC transporter C-terminal domain Golgin_A5 PF09787.9 AIN97018.1 - 4.4 6.7 31.1 0.025 14.0 7.5 3.2 1 1 2 3 3 3 0 Golgin subfamily A member 5 LCIB_C_CA PF18599.1 AIN97018.1 - 5 6.3 5.7 2.6 7.3 1.1 2.2 2 0 0 2 2 2 0 Limiting CO2-inducible proteins B/C beta carbonyic anhydrases DUF3552 PF12072.8 AIN97019.1 - 0.0007 19.1 19.6 0.0085 15.5 11.1 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF3552) Laminin_I PF06008.14 AIN97019.1 - 0.0021 17.8 11.5 0.0021 17.8 11.5 1.7 2 1 0 2 2 2 1 Laminin Domain I Spc7 PF08317.11 AIN97019.1 - 0.0023 16.9 12.5 0.0023 16.9 12.5 2.0 1 1 1 2 2 2 1 Spc7 kinetochore protein V-SNARE_C PF12352.8 AIN97019.1 - 0.0052 17.0 2.1 0.17 12.2 1.0 3.3 2 1 1 3 3 3 1 Snare region anchored in the vesicle membrane C-terminus MscS_porin PF12795.7 AIN97019.1 - 0.0088 15.6 17.8 0.017 14.7 17.8 1.4 1 0 0 1 1 1 1 Mechanosensitive ion channel porin domain MCPsignal PF00015.21 AIN97019.1 - 0.017 15.0 11.3 0.32 10.8 5.6 2.2 2 0 0 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain KxDL PF10241.9 AIN97019.1 - 0.059 13.7 10.0 0.66 10.3 5.1 2.8 2 1 0 2 2 2 0 Uncharacterized conserved protein Laminin_II PF06009.12 AIN97019.1 - 0.14 12.2 14.7 0.69 9.9 10.0 3.1 2 2 1 3 3 3 0 Laminin Domain II ApoB100_C PF12491.8 AIN97019.1 - 0.14 12.1 2.6 7.7 6.6 0.4 3.7 2 1 2 4 4 4 0 Apolipoprotein B100 C terminal TMF_DNA_bd PF12329.8 AIN97019.1 - 0.18 11.8 18.9 2.7 8.0 5.7 3.4 2 1 1 3 3 3 0 TATA element modulatory factor 1 DNA binding TMF_TATA_bd PF12325.8 AIN97019.1 - 0.21 11.8 18.9 0.25 11.5 13.9 2.3 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding Fez1 PF06818.15 AIN97019.1 - 0.22 12.0 16.7 0.05 14.1 10.9 2.0 1 1 1 2 2 2 0 Fez1 IFT57 PF10498.9 AIN97019.1 - 0.29 10.0 15.2 2.1 7.3 9.0 2.2 2 0 0 2 2 2 0 Intra-flagellar transport protein 57 WXG100 PF06013.12 AIN97019.1 - 0.32 11.2 14.4 95 3.3 9.9 3.7 2 1 0 2 2 2 0 Proteins of 100 residues with WXG YscO PF07321.12 AIN97019.1 - 0.36 10.8 18.3 0.73 9.8 11.2 2.1 2 0 0 2 2 2 0 Type III secretion protein YscO Atg14 PF10186.9 AIN97019.1 - 0.41 9.7 6.7 0.14 11.3 4.3 1.5 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 ApoLp-III PF07464.11 AIN97019.1 - 0.49 10.5 17.7 3.2 7.8 13.0 3.1 2 2 0 2 2 2 0 Apolipophorin-III precursor (apoLp-III) ApoO PF09769.9 AIN97019.1 - 0.5 10.3 5.1 4.4 7.3 0.5 2.9 2 1 1 3 3 3 0 Apolipoprotein O COG2 PF06148.11 AIN97019.1 - 0.86 9.7 13.1 0.48 10.5 6.6 3.0 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 KASH_CCD PF14662.6 AIN97019.1 - 1 9.1 19.3 0.72 9.7 6.1 2.9 2 1 1 3 3 3 0 Coiled-coil region of CCDC155 or KASH TMPIT PF07851.13 AIN97019.1 - 1.1 8.5 10.1 0.16 11.2 5.2 1.8 2 0 0 2 2 2 0 TMPIT-like protein Fib_alpha PF08702.10 AIN97019.1 - 1.8 8.7 12.0 0.68 10.1 5.2 2.3 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family Sec20 PF03908.13 AIN97019.1 - 1.9 8.5 9.3 5.7 6.9 5.6 2.8 2 1 0 2 2 2 0 Sec20 MukF_M PF17192.4 AIN97019.1 - 2.6 7.8 18.7 0.62 9.8 5.6 3.3 2 1 1 3 3 3 0 MukF middle domain DUF745 PF05335.13 AIN97019.1 - 3.3 7.4 17.0 14 5.4 11.9 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF745) Exonuc_VII_L PF02601.15 AIN97019.1 - 3.4 7.1 14.6 86 2.5 14.6 2.0 1 1 0 1 1 1 0 Exonuclease VII, large subunit DUF3450 PF11932.8 AIN97019.1 - 3.6 6.8 18.0 0.15 11.3 10.7 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) YabA PF06156.13 AIN97019.1 - 3.8 8.2 12.5 13 6.5 3.4 3.0 2 1 1 3 3 3 0 Initiation control protein YabA Synaptobrevin PF00957.21 AIN97019.1 - 6.2 6.7 7.2 5.9 6.8 2.8 2.8 2 1 1 3 3 3 0 Synaptobrevin DUF1664 PF07889.12 AIN97019.1 - 7.1 6.7 13.1 2.8 8.0 5.7 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) BORCS7 PF16088.5 AIN97019.1 - 7.2 6.9 14.7 41 4.5 8.2 3.0 2 1 0 2 2 2 0 BLOC-1-related complex sub-unit 7 TPR_MLP1_2 PF07926.12 AIN97019.1 - 7.2 6.7 22.2 11 6.1 17.3 2.5 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein DUF948 PF06103.11 AIN97019.1 - 7.5 6.9 15.5 14 6.0 10.5 3.3 2 2 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Ribosomal_S18 PF01084.20 AIN97022.1 - 0.11 12.7 0.4 0.92 9.8 0.1 2.3 2 0 0 2 2 2 0 Ribosomal protein S18 OTT_1508_deam PF14441.6 AIN97023.1 - 0.089 12.8 0.1 9.4 6.3 0.0 2.2 2 0 0 2 2 2 0 OTT_1508-like deaminase ERO1 PF04137.15 AIN97025.1 - 3.8e-88 296.0 0.0 4.5e-88 295.8 0.0 1.0 1 0 0 1 1 1 1 Endoplasmic Reticulum Oxidoreductin 1 (ERO1) DNA_pol_B PF00136.21 AIN97026.1 - 2.5e-125 418.8 0.0 3.2e-125 418.4 0.0 1.1 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.19 AIN97026.1 - 2.1e-37 129.1 0.0 4.6e-37 127.9 0.0 1.6 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain zf-DNA_Pol PF08996.10 AIN97026.1 - 0.00059 19.6 1.5 2.2 8.0 2.7 2.4 2 0 0 2 2 2 2 DNA Polymerase alpha zinc finger DNA_pol_B_2 PF03175.13 AIN97026.1 - 0.033 13.1 0.0 0.058 12.3 0.0 1.3 1 0 0 1 1 1 0 DNA polymerase type B, organellar and viral WD40 PF00400.32 AIN97027.1 - 6.5e-15 55.3 2.5 0.008 17.0 0.1 5.7 5 0 0 5 5 5 4 WD domain, G-beta repeat Ge1_WD40 PF16529.5 AIN97027.1 - 0.0038 16.2 0.3 0.073 12.0 0.0 3.2 4 0 0 4 4 4 1 WD40 region of Ge1, enhancer of mRNA-decapping protein KIP1 PF07765.12 AIN97027.1 - 0.022 14.9 0.8 0.022 14.9 0.8 4.4 4 1 2 6 6 6 0 KIP1-like protein Peptidase_M61 PF05299.12 AIN97027.1 - 2 8.8 4.7 24 5.4 0.6 3.0 2 0 0 2 2 2 0 M61 glycyl aminopeptidase Kinesin PF00225.23 AIN97030.1 - 4e-69 233.1 0.0 8.3e-68 228.8 0.0 2.3 1 1 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 AIN97030.1 - 2.6e-15 56.6 0.0 6.4e-15 55.4 0.0 1.7 1 1 0 1 1 1 1 Microtubule binding TMEM70 PF06979.12 AIN97030.1 - 0.19 12.2 0.0 0.4 11.1 0.0 1.5 1 0 0 1 1 1 0 Assembly, mitochondrial proton-transport ATP synth complex AAA_22 PF13401.6 AIN97030.1 - 1.1 9.6 3.7 20 5.5 0.5 2.7 2 0 0 2 2 2 0 AAA domain RRM_1 PF00076.22 AIN97031.1 - 1e-14 54.1 0.0 1.6e-14 53.4 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 AIN97031.1 - 0.032 14.2 0.0 0.064 13.3 0.0 1.5 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif MIF4G PF02854.19 AIN97032.1 - 2.2e-26 92.8 1.5 3.2e-26 92.3 1.5 1.3 1 0 0 1 1 1 1 MIF4G domain DUF2721 PF11026.8 AIN97032.1 - 0.059 13.3 0.1 0.14 12.0 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2721) Band_7 PF01145.25 AIN97033.1 - 2e-23 83.3 2.9 3.5e-23 82.5 2.9 1.4 1 0 0 1 1 1 1 SPFH domain / Band 7 family YdfA_immunity PF12127.8 AIN97033.1 - 6.5e-05 22.1 1.7 8.3e-05 21.8 1.7 1.1 1 0 0 1 1 1 1 SigmaW regulon antibacterial ANAPC4_WD40 PF12894.7 AIN97034.1 - 0.094 13.0 0.0 0.95 9.8 0.0 2.3 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 AIN97034.1 - 0.13 13.1 1.8 3 8.9 0.0 3.6 3 0 0 3 3 3 0 WD domain, G-beta repeat Nop PF01798.18 AIN97035.1 - 8.5e-12 45.0 1.3 2.4e-11 43.5 0.1 2.0 2 0 0 2 2 2 1 snoRNA binding domain, fibrillarin Prp31_C PF09785.9 AIN97035.1 - 0.029 15.3 4.6 0.031 15.2 2.6 2.1 2 0 0 2 2 2 0 Prp31 C terminal domain CLU PF13236.6 AIN97036.1 - 1.1e-09 38.5 0.0 1.3e-08 35.0 0.0 2.5 1 1 0 1 1 1 1 Clustered mitochondria eIF3_p135 PF12807.7 AIN97036.1 - 7.4e-05 22.9 0.0 0.00014 22.0 0.0 1.4 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit 135 CLU PF13236.6 AIN97037.1 - 0.001 19.0 0.0 0.0046 16.8 0.0 2.1 1 1 0 1 1 1 1 Clustered mitochondria TPR_2 PF07719.17 AIN97037.1 - 0.008 16.2 4.1 0.16 12.2 0.1 4.3 4 0 0 4 4 4 1 Tetratricopeptide repeat eIF3_p135 PF12807.7 AIN97037.1 - 0.014 15.5 0.0 0.032 14.3 0.0 1.5 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit 135 TPR_14 PF13428.6 AIN97037.1 - 2.1 9.4 8.0 1.8 9.6 0.0 4.6 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF1682 PF07946.14 AIN97039.1 - 0.0047 16.2 1.2 0.0047 16.2 1.2 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF1682) ANAPC3 PF12895.7 AIN97039.1 - 0.0058 16.8 0.0 0.02 15.1 0.0 2.0 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 DUF3522 PF12036.8 AIN97040.1 - 4.2e-46 157.6 14.2 5.1e-46 157.3 14.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3522) Cytochrom_B561 PF03188.16 AIN97040.1 - 0.043 13.9 9.7 0.098 12.8 0.1 3.5 2 2 1 3 3 3 0 Eukaryotic cytochrome b561 TMEM107 PF14995.6 AIN97040.1 - 0.073 13.5 1.4 0.073 13.5 1.4 2.9 3 1 0 3 3 3 0 Transmembrane protein DUF3784 PF12650.7 AIN97040.1 - 0.085 13.1 0.1 0.085 13.1 0.1 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF3784) zf-RING_2 PF13639.6 AIN97041.1 - 3.7e-10 40.0 7.9 8.3e-10 38.9 7.9 1.7 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 AIN97041.1 - 4.9e-08 32.9 6.3 5.6e-08 32.7 5.1 1.8 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4 PF00097.25 AIN97041.1 - 1.1e-07 31.6 7.0 2.1e-07 30.7 7.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 AIN97041.1 - 1.4e-07 31.7 9.2 1.1e-06 28.9 9.2 2.3 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_11 PF17123.5 AIN97041.1 - 2.5e-07 30.3 4.5 6.6e-07 29.0 4.5 1.8 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 AIN97041.1 - 3.3e-07 30.0 8.3 6e-07 29.2 8.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 AIN97041.1 - 4.4e-06 26.5 3.6 1e-05 25.3 3.6 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 AIN97041.1 - 1.5e-05 24.9 1.6 3.2e-05 23.9 1.6 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_5 PF14634.6 AIN97041.1 - 2e-05 24.5 5.1 4.1e-05 23.4 5.1 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 AIN97041.1 - 7.2e-05 22.9 6.1 0.00016 21.8 6.1 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 AIN97041.1 - 0.0057 16.5 6.9 0.34 10.8 7.9 2.4 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 CpXC PF14353.6 AIN97041.1 - 0.14 12.2 1.3 0.23 11.5 1.3 1.5 1 1 0 1 1 1 0 CpXC protein zf-RING_6 PF14835.6 AIN97041.1 - 0.22 11.4 2.4 0.38 10.6 1.6 1.8 2 1 0 2 2 1 0 zf-RING of BARD1-type protein Zn_ribbon_17 PF17120.5 AIN97041.1 - 0.3 10.7 5.4 0.88 9.2 5.4 1.8 1 1 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-C3H2C3 PF17122.5 AIN97041.1 - 0.35 10.9 6.6 1.8 8.7 6.6 2.2 1 1 1 2 2 2 0 Zinc-finger FANCL_C PF11793.8 AIN97041.1 - 0.4 10.9 7.1 4.5 7.5 6.9 2.8 1 1 1 2 2 2 0 FANCL C-terminal domain UBZ_FAAP20 PF15750.5 AIN97041.1 - 0.54 10.2 5.0 0.84 9.6 0.1 2.6 2 0 0 2 2 2 0 Ubiquitin-binding zinc-finger DnaJ PF00226.31 AIN97042.1 - 6.6e-07 29.4 0.0 1.1e-06 28.7 0.0 1.3 1 0 0 1 1 1 1 DnaJ domain Telomerase_RBD PF12009.8 AIN97042.1 - 0.14 12.3 0.5 0.19 11.8 0.5 1.3 1 1 0 1 1 1 0 Telomerase ribonucleoprotein complex - RNA binding domain PsaN PF05479.11 AIN97043.1 - 0.025 14.8 0.4 0.039 14.1 0.4 1.4 1 0 0 1 1 1 0 Photosystem I reaction centre subunit N (PSAN or PSI-N) Peptidase_M26_C PF07580.14 AIN97043.1 - 0.056 11.9 0.1 0.075 11.5 0.1 1.1 1 0 0 1 1 1 0 M26 IgA1-specific Metallo-endopeptidase C-terminal region GCR1_C PF12550.8 AIN97043.1 - 0.075 13.4 1.2 0.13 12.6 0.4 1.9 2 0 0 2 2 2 0 Transcriptional activator of glycolytic enzymes Pkinase PF00069.25 AIN97044.1 - 2.1e-64 217.4 0.0 2.8e-64 217.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 AIN97044.1 - 9.4e-38 130.0 0.0 1.4e-37 129.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 AIN97044.1 - 4.2e-05 23.0 0.0 6.4e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 Kinase-like LRR_6 PF13516.6 AIN97044.1 - 8.8e-05 22.3 0.6 0.37 11.0 0.2 3.5 3 0 0 3 3 3 2 Leucine Rich repeat LRR_4 PF12799.7 AIN97044.1 - 0.00046 20.5 0.2 0.0012 19.2 0.2 1.7 1 0 0 1 1 1 1 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 AIN97044.1 - 0.00062 19.5 0.4 0.0065 16.2 0.7 2.2 1 1 0 1 1 1 1 Leucine rich repeat LRR_1 PF00560.33 AIN97044.1 - 0.003 17.9 0.2 7.2 7.6 0.0 3.1 2 0 0 2 2 2 2 Leucine Rich Repeat Kdo PF06293.14 AIN97044.1 - 0.0067 15.8 0.0 0.012 14.9 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 AIN97044.1 - 0.0077 15.9 0.0 0.015 14.9 0.0 1.4 1 0 0 1 1 1 1 RIO1 family zf-RING_11 PF17123.5 AIN97044.1 - 0.058 13.2 0.9 0.92 9.3 0.2 2.7 2 0 0 2 2 2 0 RING-like zinc finger Pkinase_fungal PF17667.1 AIN97044.1 - 0.06 12.1 0.0 0.097 11.4 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase APH PF01636.23 AIN97044.1 - 0.099 12.5 0.0 0.61 10.0 0.0 2.0 1 1 1 2 2 2 0 Phosphotransferase enzyme family Arf PF00025.21 AIN97045.1 - 1.2e-67 226.7 0.1 1.5e-67 226.5 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 AIN97045.1 - 3.9e-13 49.7 0.0 6.7e-13 48.9 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 AIN97045.1 - 1.7e-11 43.9 0.0 2e-11 43.6 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 AIN97045.1 - 1.1e-10 41.3 0.2 7.3e-08 32.0 0.1 2.3 1 1 1 2 2 2 2 G-protein alpha subunit Ras PF00071.22 AIN97045.1 - 1.1e-10 41.3 0.0 1.4e-10 41.1 0.0 1.1 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.12 AIN97045.1 - 1.5e-08 34.3 0.0 1.8e-08 34.0 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 AIN97045.1 - 8.7e-06 25.8 0.0 1.3e-05 25.2 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase AP_endonuc_2 PF01261.24 AIN97045.1 - 0.0062 16.0 0.0 0.013 14.9 0.0 1.5 1 1 0 1 1 1 1 Xylose isomerase-like TIM barrel FeoB_N PF02421.18 AIN97045.1 - 0.0089 15.6 0.4 0.06 12.9 0.4 2.0 1 1 0 1 1 1 1 Ferrous iron transport protein B GTP_EFTU PF00009.27 AIN97046.1 - 3.4e-51 173.6 0.0 5.8e-51 172.8 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 AIN97046.1 - 2.1e-41 140.7 0.0 5.5e-41 139.4 0.0 1.7 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 AIN97046.1 - 7.7e-16 58.2 1.3 1.4e-15 57.4 0.5 2.0 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 AIN97046.1 - 8.6e-06 25.8 0.0 0.003 17.6 0.0 2.5 2 0 0 2 2 2 2 50S ribosome-binding GTPase SRPRB PF09439.10 AIN97046.1 - 0.0035 16.8 0.1 0.016 14.7 0.1 2.3 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit FlpD PF02662.16 AIN97046.1 - 0.0038 17.2 0.0 0.011 15.8 0.0 1.7 1 0 0 1 1 1 1 Methyl-viologen-reducing hydrogenase, delta subunit GTP_EFTU_D4 PF14578.6 AIN97046.1 - 0.0088 15.9 1.1 0.019 14.9 0.2 2.0 2 0 0 2 2 2 1 Elongation factor Tu domain 4 Semialdhyde_dhC PF02774.18 AIN97046.1 - 0.088 12.9 0.3 0.75 9.8 0.1 2.1 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, dimerisation domain Guanylate_cyc PF00211.20 AIN97047.1 - 3.1e-36 124.7 0.0 5.1e-36 124.0 0.0 1.3 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain FAM163 PF15069.6 AIN97047.1 - 0.076 13.5 0.0 0.39 11.1 0.0 2.2 3 0 0 3 3 3 0 FAM163 family Guanylate_cyc PF00211.20 AIN97048.1 - 2.8e-36 124.8 0.0 5.1e-36 124.0 0.0 1.4 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain FAM163 PF15069.6 AIN97048.1 - 0.14 12.6 0.0 0.43 11.0 0.0 1.7 2 0 0 2 2 2 0 FAM163 family Peripla_BP_6 PF13458.6 AIN97049.1 - 5.1e-10 39.5 0.2 1.4e-09 38.1 0.2 1.8 1 1 0 1 1 1 1 Periplasmic binding protein TPR_2 PF07719.17 AIN97052.1 - 5.1e-17 60.6 1.7 0.00026 20.9 0.0 4.5 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_12 PF13424.6 AIN97052.1 - 9e-09 35.5 0.9 0.064 13.6 0.2 3.7 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 AIN97052.1 - 5.8e-08 32.2 6.6 0.012 15.4 0.0 4.5 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_6 PF13174.6 AIN97052.1 - 3.2e-06 27.4 0.2 0.071 13.8 0.0 4.7 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_8 PF13181.6 AIN97052.1 - 4.5e-06 26.5 6.4 0.51 10.7 0.1 4.4 5 0 0 5 5 4 3 Tetratricopeptide repeat TPR_19 PF14559.6 AIN97052.1 - 1.8e-05 25.2 0.1 0.00014 22.3 0.0 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.6 AIN97052.1 - 6.9e-05 22.6 5.0 0.013 15.4 0.1 4.2 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_14 PF13428.6 AIN97052.1 - 9.4e-05 22.9 0.2 8.8 7.4 0.0 4.1 3 1 1 4 4 3 1 Tetratricopeptide repeat TPR_10 PF13374.6 AIN97052.1 - 0.00026 20.8 2.8 1.8 8.5 0.2 3.8 3 0 0 3 3 3 1 Tetratricopeptide repeat ANAPC3 PF12895.7 AIN97052.1 - 0.0013 18.9 4.5 0.012 15.8 0.0 3.0 3 1 1 4 4 4 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.6 AIN97052.1 - 0.0045 17.3 0.3 15 6.2 0.0 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_16 PF13432.6 AIN97052.1 - 0.0057 17.3 0.0 2 9.1 0.0 3.7 2 2 0 2 2 2 1 Tetratricopeptide repeat TPR_21 PF09976.9 AIN97052.1 - 0.017 14.8 0.1 0.29 10.8 0.0 2.6 2 1 1 3 3 3 0 Tetratricopeptide repeat-like domain PknG_TPR PF16918.5 AIN97052.1 - 0.027 13.2 0.0 0.043 12.5 0.0 1.3 1 0 0 1 1 1 0 Protein kinase G tetratricopeptide repeat TPR_11 PF13414.6 AIN97052.1 - 0.029 14.1 6.1 6 6.6 0.0 4.1 3 1 0 3 3 3 0 TPR repeat ROF PF07073.12 AIN97052.1 - 0.055 13.6 0.4 0.14 12.3 0.4 1.7 1 0 0 1 1 1 0 Modulator of Rho-dependent transcription termination (ROF) DUF896 PF05979.12 AIN97053.1 - 0.023 14.5 1.3 0.054 13.4 1.3 1.6 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF896) SAM_Exu PF18609.1 AIN97053.1 - 0.081 13.0 1.4 0.22 11.6 1.4 1.7 1 0 0 1 1 1 0 Exuperantia SAM-like domain Atrophin-1 PF03154.15 AIN97053.1 - 4.7 5.4 10.1 1.8 6.8 2.3 2.4 2 0 0 2 2 2 0 Atrophin-1 family Peptidase_M20 PF01546.28 AIN97054.1 - 2.6e-11 43.6 0.1 4.2e-11 42.9 0.1 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 AIN97054.1 - 6.3e-11 42.2 0.0 9.2e-10 38.4 0.0 2.3 2 0 0 2 2 2 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 AIN97054.1 - 1.4e-05 24.9 0.0 4.6e-05 23.2 0.0 1.8 2 0 0 2 2 2 1 Peptidase family M28 Peptidase_M42 PF05343.14 AIN97054.1 - 1.6e-05 24.1 0.1 0.00013 21.1 0.1 2.1 2 0 0 2 2 2 1 M42 glutamyl aminopeptidase DUF5374 PF17344.2 AIN97054.1 - 0.13 12.2 0.0 0.23 11.4 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5374) FAP206 PF12018.8 AIN97055.1 - 4.5e-06 26.4 0.0 1.2e-05 24.9 0.0 1.7 1 1 0 1 1 1 1 Domain of unknown function Kinesin PF00225.23 AIN97056.1 - 3.6e-40 137.9 0.0 6.8e-25 87.7 0.0 2.2 2 0 0 2 2 2 2 Kinesin motor domain Microtub_bd PF16796.5 AIN97056.1 - 6.7e-09 35.8 0.0 4e-07 30.1 0.0 2.7 3 0 0 3 3 3 1 Microtubule binding AAA_16 PF13191.6 AIN97056.1 - 0.19 12.1 3.4 0.42 11.0 1.0 3.0 2 2 0 2 2 2 0 AAA ATPase domain AAA_7 PF12775.7 AIN97056.1 - 0.24 10.9 0.1 0.51 9.8 0.1 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region WD40 PF00400.32 AIN97057.1 - 5.8e-26 90.2 7.5 4.7e-07 30.4 0.1 5.9 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 AIN97057.1 - 3.8e-11 43.1 0.0 0.11 12.8 0.0 4.5 2 1 2 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 AIN97057.1 - 1.5e-06 27.4 0.1 0.0095 14.9 0.0 3.3 1 1 2 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 AIN97057.1 - 1.8e-05 24.5 0.2 0.61 10.1 0.0 3.8 4 0 0 4 4 4 2 WD40-like Beta Propeller Repeat Nup160 PF11715.8 AIN97057.1 - 0.001 17.8 0.3 0.89 8.1 0.0 3.2 1 1 1 3 3 3 2 Nucleoporin Nup120/160 Frtz PF11768.8 AIN97057.1 - 0.0018 16.7 0.0 0.0046 15.3 0.0 1.5 1 1 1 2 2 2 1 WD repeat-containing and planar cell polarity effector protein Fritz eIF2A PF08662.11 AIN97057.1 - 0.014 15.3 0.0 0.53 10.1 0.0 2.2 1 1 1 2 2 2 0 Eukaryotic translation initiation factor eIF2A Proteasome_A_N PF10584.9 AIN97057.1 - 0.14 11.9 0.1 9.1 6.1 0.0 2.8 2 0 0 2 2 2 0 Proteasome subunit A N-terminal signature RCC1 PF00415.18 AIN97058.1 - 1.2e-55 185.9 30.0 2.2e-13 50.6 0.8 8.5 7 1 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 AIN97058.1 - 4.7e-28 96.4 46.3 1e-11 44.3 3.1 8.5 9 0 0 9 9 9 6 Regulator of chromosome condensation (RCC1) repeat BTB_2 PF02214.22 AIN97058.1 - 1.2e-06 28.7 0.0 0.079 13.3 0.0 2.4 2 0 0 2 2 2 2 BTB/POZ domain PALP PF00291.25 AIN97059.1 - 5.5e-69 232.8 0.1 7e-69 232.5 0.1 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Bmp PF02608.14 AIN97059.1 - 0.0026 16.8 0.0 0.14 11.1 0.0 2.3 1 1 1 2 2 2 2 ABC transporter substrate-binding protein PnrA-like 2Fe-2S_thioredx PF01257.19 AIN97061.1 - 9.2e-48 161.8 0.0 1.2e-47 161.4 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin-like [2Fe-2S] ferredoxin Histone_H2A_C PF16211.5 AIN97062.1 - 6.3e-12 45.0 0.5 1.5e-11 43.8 0.5 1.7 1 0 0 1 1 1 1 C-terminus of histone H2A Histone PF00125.24 AIN97062.1 - 3.3e-10 40.4 0.0 5.6e-10 39.7 0.0 1.4 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 zf-C3HC4_2 PF13923.6 AIN97063.1 - 3.3e-07 30.0 14.7 3.3e-07 30.0 14.7 3.2 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 AIN97063.1 - 2.7e-05 23.9 17.7 2.7e-05 23.9 17.7 3.4 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 AIN97063.1 - 2.7e-05 24.1 10.2 2.7e-05 24.1 10.2 2.8 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4 PF00097.25 AIN97063.1 - 6.1e-05 22.8 13.8 6.1e-05 22.8 13.8 3.1 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 AIN97063.1 - 0.00076 19.8 18.1 0.00076 19.8 18.1 4.0 4 0 0 4 4 4 1 Ring finger domain zf-C3HC4_4 PF15227.6 AIN97063.1 - 0.0033 17.5 15.4 0.0033 17.5 15.4 2.4 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 AIN97063.1 - 0.0058 16.6 14.0 0.0058 16.6 14.0 3.2 3 0 0 3 3 3 1 zinc-RING finger domain LSM PF01423.22 AIN97064.1 - 9e-07 28.5 0.2 1e-05 25.1 0.2 2.1 1 1 0 1 1 1 1 LSM domain DUF667 PF05018.13 AIN97065.1 - 0.17 11.6 0.0 0.44 10.2 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF667) dsrm PF00035.26 AIN97067.1 - 0.0022 18.6 0.0 3.2 8.5 0.0 2.8 2 0 0 2 2 2 2 Double-stranded RNA binding motif DUF4793 PF16041.5 AIN97067.1 - 0.21 11.8 0.3 0.48 10.6 0.3 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4793) Dus PF01207.17 AIN97069.1 - 5.1e-51 173.6 0.0 8.6e-51 172.9 0.0 1.3 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) GLYCAM-1 PF05242.11 AIN97069.1 - 0.066 13.3 4.1 0.13 12.3 4.1 1.4 1 0 0 1 1 1 0 Glycosylation-dependent cell adhesion molecule 1 (GlyCAM-1) Robl_LC7 PF03259.17 AIN97069.1 - 0.18 11.6 0.1 0.37 10.6 0.1 1.4 1 0 0 1 1 1 0 Roadblock/LC7 domain dCMP_cyt_deam_1 PF00383.23 AIN97070.1 - 8.7e-12 44.8 2.5 1.4e-11 44.2 2.5 1.3 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region dCMP_cyt_deam_2 PF08211.12 AIN97070.1 - 8.6e-10 38.9 2.1 2.9e-07 30.7 1.4 2.1 2 0 0 2 2 2 2 Cytidine and deoxycytidylate deaminase zinc-binding region LmjF365940-deam PF14421.6 AIN97070.1 - 0.0044 16.6 2.2 0.11 12.1 0.0 2.0 1 1 1 2 2 2 2 A distinct subfamily of CDD/CDA-like deaminases Pheromone PF08015.11 AIN97071.1 - 0.029 15.4 2.0 0.029 15.4 2.0 4.8 5 1 1 6 6 6 0 Fungal mating-type pheromone Sec20 PF03908.13 AIN97072.1 - 0.00014 21.7 1.8 0.00014 21.7 1.8 1.9 2 0 0 2 2 2 1 Sec20 V-SNARE_C PF12352.8 AIN97072.1 - 0.01 16.1 2.5 0.025 14.8 2.5 1.8 1 0 0 1 1 1 0 Snare region anchored in the vesicle membrane C-terminus SNARE PF05739.19 AIN97072.1 - 0.051 13.6 2.7 0.23 11.5 2.7 2.2 1 0 0 1 1 1 0 SNARE domain Phage_holin_3_6 PF07332.11 AIN97072.1 - 0.056 13.5 0.2 0.19 11.8 0.2 1.9 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III MLD PF11647.8 AIN97072.1 - 0.52 10.6 3.1 4.2 7.7 0.3 2.4 2 0 0 2 2 2 0 Membrane Localization Domain V-SNARE PF05008.15 AIN97072.1 - 0.56 10.6 3.7 0.98 9.8 0.2 2.4 2 0 0 2 2 2 0 Vesicle transport v-SNARE protein N-terminus DUF2203 PF09969.9 AIN97072.1 - 2.3 8.9 7.3 25 5.6 2.4 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) Filament PF00038.21 AIN97072.1 - 9 5.8 12.5 0.19 11.3 2.4 2.6 3 0 0 3 3 3 0 Intermediate filament protein Pkinase PF00069.25 AIN97073.1 - 2.4e-61 207.4 0.0 4.2e-61 206.6 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 AIN97073.1 - 1.1e-39 136.3 0.0 4.7e-38 130.9 0.0 2.2 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 AIN97073.1 - 5.9e-07 28.6 0.0 2.3e-06 26.6 0.0 1.9 2 0 0 2 2 2 1 Fungal protein kinase Kinase-like PF14531.6 AIN97073.1 - 3e-06 26.8 0.0 8.4e-06 25.3 0.0 1.6 1 1 1 2 2 2 1 Kinase-like APH PF01636.23 AIN97073.1 - 0.0064 16.4 0.0 0.014 15.3 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family ANTH PF07651.16 AIN97073.1 - 0.0077 15.2 0.0 0.017 14.2 0.0 1.5 1 0 0 1 1 1 1 ANTH domain Kdo PF06293.14 AIN97073.1 - 0.017 14.5 0.0 0.033 13.5 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family zf-RING_2 PF13639.6 AIN97074.1 - 4.4e-08 33.3 3.7 1.5e-07 31.6 3.7 2.0 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 AIN97074.1 - 1.9e-06 27.8 2.2 1.9e-06 27.8 2.2 2.6 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4 PF00097.25 AIN97074.1 - 4.3e-05 23.3 3.2 4.3e-05 23.3 3.2 2.6 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 AIN97074.1 - 5.6e-05 22.9 6.5 0.0011 18.8 5.2 3.3 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 AIN97074.1 - 0.00019 21.4 5.5 0.00056 19.8 5.5 1.9 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.7 AIN97074.1 - 0.00029 21.0 2.1 0.0012 19.1 2.1 2.1 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_11 PF17123.5 AIN97074.1 - 0.00037 20.2 2.2 0.0012 18.5 2.2 2.0 1 0 0 1 1 1 1 RING-like zinc finger zf-Nse PF11789.8 AIN97074.1 - 0.015 15.1 3.3 0.034 14.0 3.3 1.6 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-C3HC4_4 PF15227.6 AIN97074.1 - 0.016 15.4 4.2 0.016 15.4 4.2 3.3 2 1 0 2 2 2 0 zinc finger of C3HC4-type, RING Yop-YscD_cpl PF16697.5 AIN97075.1 - 0.14 12.5 0.0 0.37 11.2 0.0 1.6 1 0 0 1 1 1 0 Inner membrane component of T3SS, cytoplasmic domain Na_trans_assoc PF06512.13 AIN97075.1 - 8.7 6.6 16.4 0.26 11.5 5.1 2.9 3 0 0 3 3 3 0 Sodium ion transport-associated N6-adenineMlase PF10237.9 AIN97076.1 - 4.7e-33 114.3 1.6 7.5e-33 113.6 1.6 1.3 1 0 0 1 1 1 1 Probable N6-adenine methyltransferase Uds1 PF15456.6 AIN97076.1 - 0.0093 16.1 4.6 0.029 14.5 4.6 1.8 1 0 0 1 1 1 1 Up-regulated During Septation MTS PF05175.14 AIN97076.1 - 0.16 11.5 2.0 0.35 10.4 0.0 2.4 3 0 0 3 3 3 0 Methyltransferase small domain DHHW PF14286.6 AIN97076.1 - 0.18 11.1 1.0 0.28 10.5 1.0 1.2 1 0 0 1 1 1 0 DHHW protein DUF3138 PF11336.8 AIN97076.1 - 5.1 5.6 6.1 8.1 4.9 6.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) PKcGMP_CC PF16808.5 AIN97078.1 - 0.099 12.5 0.1 1 9.2 0.0 2.7 2 0 0 2 2 2 0 Coiled-coil N-terminus of cGMP-dependent protein kinase BLOC1_2 PF10046.9 AIN97078.1 - 0.22 11.8 3.6 0.14 12.4 0.8 2.1 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Atg14 PF10186.9 AIN97078.1 - 0.24 10.4 7.2 0.056 12.5 3.4 1.8 2 1 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 Cnn_1N PF07989.11 AIN97078.1 - 5.3 7.3 11.1 4.4 7.5 2.1 3.4 3 0 0 3 3 3 0 Centrosomin N-terminal motif 1 Mito_fiss_reg PF05308.11 AIN97079.1 - 0.0063 16.6 0.1 0.0063 16.6 0.1 3.1 3 1 0 3 3 3 1 Mitochondrial fission regulator SH3_16 PF18348.1 AIN97079.1 - 0.18 11.7 0.9 0.66 9.8 0.0 2.3 2 0 0 2 2 2 0 Bacterial dipeptidyl-peptidase Sh3 domain DnaJ PF00226.31 AIN97080.1 - 1.1e-09 38.3 0.0 1.9e-09 37.5 0.0 1.4 1 0 0 1 1 1 1 DnaJ domain ORF_12_N PF18042.1 AIN97080.1 - 0.13 12.7 0.0 0.24 11.8 0.0 1.5 1 0 0 1 1 1 0 ORF 12 gene product N-terminal PhzC-PhzF PF02567.16 AIN97082.1 - 9.3e-37 127.0 0.2 4.7e-25 88.6 0.0 4.3 3 1 0 3 3 3 3 Phenazine biosynthesis-like protein Sigma70_r4 PF04545.16 AIN97082.1 - 0.021 14.3 0.1 0.042 13.4 0.1 1.5 1 0 0 1 1 1 0 Sigma-70, region 4 DUF4604 PF15377.6 AIN97082.1 - 3.7 7.9 5.0 1.6 9.1 2.3 1.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4604) Pkinase PF00069.25 AIN97083.1 - 6.5e-59 199.4 0.0 9e-59 199.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 AIN97083.1 - 4.5e-39 134.3 0.0 6.6e-37 127.2 0.0 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 AIN97083.1 - 0.0023 17.3 0.1 0.0096 15.3 0.0 1.9 2 1 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 AIN97083.1 - 0.0047 15.8 0.0 0.019 13.7 0.0 1.9 2 0 0 2 2 2 1 Fungal protein kinase Haspin_kinase PF12330.8 AIN97083.1 - 0.014 14.4 0.0 0.026 13.5 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain TFIIF_alpha PF05793.12 AIN97083.1 - 0.02 13.5 17.0 0.035 12.7 17.0 1.4 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Nop14 PF04147.12 AIN97083.1 - 0.024 12.9 20.9 0.034 12.4 20.9 1.1 1 0 0 1 1 1 0 Nop14-like family ABC1 PF03109.16 AIN97083.1 - 0.15 12.2 0.0 0.36 11.0 0.0 1.6 1 0 0 1 1 1 0 ABC1 family BUD22 PF09073.10 AIN97083.1 - 0.37 10.1 28.3 0.68 9.2 28.3 1.3 1 0 0 1 1 1 0 BUD22 YL1 PF05764.13 AIN97083.1 - 0.51 10.4 16.2 0.98 9.5 16.2 1.4 1 0 0 1 1 1 0 YL1 nuclear protein Apt1 PF10351.9 AIN97083.1 - 2.9 6.6 10.9 5.1 5.8 10.9 1.3 1 0 0 1 1 1 0 Golgi-body localisation protein domain SAPS PF04499.15 AIN97083.1 - 4 6.1 7.2 5.8 5.6 7.2 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein DUF4637 PF15470.6 AIN97083.1 - 8.9 6.0 14.6 20 4.9 14.6 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) CDC45 PF02724.14 AIN97083.1 - 9.9 4.3 21.2 15 3.7 21.2 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF1906 PF08924.11 AIN97085.1 - 0.17 12.0 0.3 0.34 11.0 0.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1906) ERM PF00769.19 AIN97087.1 - 0.0024 17.7 4.8 0.0024 17.7 4.8 4.5 3 1 2 5 5 5 1 Ezrin/radixin/moesin family AAA PF00004.29 AIN97088.1 - 2.5e-09 37.7 0.0 5.5e-08 33.3 0.0 2.4 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 AIN97088.1 - 9.4e-06 26.1 0.0 4.8e-05 23.8 0.0 2.2 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 AIN97088.1 - 3e-05 24.3 0.0 9.9e-05 22.6 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 AIN97088.1 - 9.4e-05 22.2 0.3 0.00056 19.7 0.2 2.3 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.14 AIN97088.1 - 0.0001 22.3 0.0 0.0021 18.1 0.0 2.8 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) Rad17 PF03215.15 AIN97088.1 - 0.00011 22.2 0.0 0.0015 18.5 0.0 2.3 2 0 0 2 2 2 1 Rad17 P-loop domain AAA_28 PF13521.6 AIN97088.1 - 0.00021 21.6 0.1 0.00064 20.0 0.1 1.8 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 AIN97088.1 - 0.00037 21.1 0.0 0.0011 19.5 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 AIN97088.1 - 0.00088 19.5 1.0 0.0022 18.2 0.0 2.3 2 0 0 2 2 1 1 AAA domain RuvB_N PF05496.12 AIN97088.1 - 0.0014 18.4 0.1 0.0029 17.4 0.1 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain NTPase_1 PF03266.15 AIN97088.1 - 0.0033 17.3 0.0 0.0065 16.4 0.0 1.4 1 0 0 1 1 1 1 NTPase RsgA_GTPase PF03193.16 AIN97088.1 - 0.0071 16.3 0.0 0.014 15.3 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase AAA_25 PF13481.6 AIN97088.1 - 0.0088 15.6 0.0 0.024 14.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_assoc_2 PF16193.5 AIN97088.1 - 0.0091 16.3 0.0 0.064 13.6 0.0 2.3 1 1 1 2 2 2 1 AAA C-terminal domain AAA_19 PF13245.6 AIN97088.1 - 0.012 15.9 0.1 0.06 13.7 0.1 2.1 1 1 0 1 1 1 0 AAA domain AAA_17 PF13207.6 AIN97088.1 - 0.025 15.0 0.0 0.083 13.3 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 AIN97088.1 - 0.04 13.4 0.0 0.087 12.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_14 PF13173.6 AIN97088.1 - 0.055 13.5 0.0 0.18 11.9 0.0 1.9 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 AIN97088.1 - 0.12 12.9 0.1 0.52 10.8 0.0 2.1 2 0 0 2 2 2 0 ABC transporter TsaE PF02367.17 AIN97088.1 - 0.13 12.3 0.0 0.25 11.4 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE dNK PF01712.19 AIN97088.1 - 0.13 12.1 0.0 0.23 11.3 0.0 1.3 1 0 0 1 1 1 0 Deoxynucleoside kinase NACHT PF05729.12 AIN97088.1 - 0.18 11.7 0.0 0.48 10.3 0.0 1.7 1 0 0 1 1 1 0 NACHT domain RRM_1 PF00076.22 AIN97089.1 - 7.6e-13 48.1 0.3 9.9e-09 34.9 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 AIN97089.1 - 0.0016 18.1 0.0 0.0028 17.3 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SET_assoc PF11767.8 AIN97089.1 - 0.059 13.0 0.3 2.2 8.0 0.1 2.6 2 1 0 2 2 2 0 Histone lysine methyltransferase SET associated AsnC_trans_reg PF01037.21 AIN97089.1 - 0.064 13.2 0.1 4.2 7.4 0.0 2.6 2 0 0 2 2 2 0 Lrp/AsnC ligand binding domain RRM_7 PF16367.5 AIN97089.1 - 0.13 12.4 0.1 48 4.2 0.0 3.1 2 1 1 3 3 3 0 RNA recognition motif SIP PF04954.13 AIN97089.1 - 0.13 12.8 0.0 0.35 11.4 0.1 1.7 2 0 0 2 2 2 0 Siderophore-interacting protein ELF PF03317.13 AIN97090.1 - 0.017 15.1 0.0 0.031 14.3 0.0 1.4 1 0 0 1 1 1 0 ELF protein LPP PF04728.13 AIN97091.1 - 0.42 11.1 3.5 35 4.9 0.1 3.6 3 0 0 3 3 3 0 Lipoprotein leucine-zipper Baculo_PEP_C PF04513.12 AIN97091.1 - 1.6 8.8 5.1 64 3.6 1.2 3.2 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF2205 PF10224.9 AIN97091.1 - 2.3 8.3 5.4 6.2 6.9 0.8 3.0 2 0 0 2 2 2 0 Short coiled-coil protein SF-assemblin PF06705.11 AIN97091.1 - 2.4 7.4 6.4 2.8 7.2 0.9 2.5 2 0 0 2 2 2 0 SF-assemblin/beta giardin Metallophos PF00149.28 AIN97092.1 - 0.0011 19.6 0.0 0.0022 18.5 0.0 1.5 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase T7SS_ESX_EspC PF10824.8 AIN97092.1 - 0.19 12.2 1.1 0.3 11.6 1.1 1.3 1 0 0 1 1 1 0 Excreted virulence factor EspC, type VII ESX diderm Cation_ATPase_C PF00689.21 AIN97094.1 - 1.3e-38 132.5 7.9 1.3e-38 132.5 7.9 2.0 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 AIN97094.1 - 1.1e-31 109.8 0.5 1.1e-31 109.8 0.5 2.2 3 0 0 3 3 3 1 E1-E2 ATPase Cation_ATPase PF13246.6 AIN97094.1 - 4.2e-30 103.7 0.0 8.5e-30 102.7 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 AIN97094.1 - 5.8e-15 56.1 1.4 1.4e-10 41.9 0.4 3.1 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Peptidase_M50B PF13398.6 AIN97094.1 - 0.00019 21.1 2.8 0.00046 19.9 0.6 2.4 2 0 0 2 2 2 1 Peptidase M50B-like Hydrolase_3 PF08282.12 AIN97094.1 - 0.00026 20.8 0.9 0.00053 19.8 0.9 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase ACBP PF00887.19 AIN97095.1 - 2.2e-30 104.7 2.6 5.3e-16 58.6 0.0 3.4 3 0 0 3 3 3 2 Acyl CoA binding protein ACBP PF00887.19 AIN97096.1 - 5.7e-27 93.8 0.2 6.5e-27 93.6 0.2 1.1 1 0 0 1 1 1 1 Acyl CoA binding protein ACBP PF00887.19 AIN97098.1 - 7.3e-26 90.2 0.1 8.1e-26 90.1 0.1 1.0 1 0 0 1 1 1 1 Acyl CoA binding protein Terminase_6 PF03237.15 AIN97098.1 - 0.12 12.0 0.0 0.13 11.9 0.0 1.1 1 0 0 1 1 1 0 Terminase-like family Abhydrolase_1 PF00561.20 AIN97099.1 - 0.00079 19.1 0.0 0.0016 18.1 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 AIN97099.1 - 0.0011 19.7 0.1 0.0014 19.3 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.13 AIN97099.1 - 0.022 14.5 0.0 0.039 13.7 0.0 1.4 1 0 0 1 1 1 0 PGAP1-like protein EF-hand_13 PF17958.1 AIN97100.1 - 2.7e-21 75.2 0.0 6.2e-21 74.0 0.0 1.5 1 0 0 1 1 1 1 EF-hand domain EF-hand_7 PF13499.6 AIN97100.1 - 5.1e-19 68.5 1.3 1.4e-15 57.5 0.1 2.6 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 AIN97100.1 - 5.2e-05 22.8 0.2 0.0012 18.6 0.0 3.1 3 0 0 3 3 3 1 EF-hand domain EF-hand_5 PF13202.6 AIN97100.1 - 0.00014 21.1 0.2 0.00075 18.9 0.0 2.2 2 0 0 2 2 2 1 EF hand EF-hand_1 PF00036.32 AIN97100.1 - 0.00061 19.2 0.0 0.0036 16.8 0.0 2.4 2 0 0 2 2 2 1 EF hand EF-hand_8 PF13833.6 AIN97100.1 - 0.069 13.0 0.0 0.41 10.5 0.0 2.3 2 0 0 2 2 2 0 EF-hand domain pair VASt PF16016.5 AIN97102.1 - 1.4e-15 58.0 0.0 2.8e-15 57.0 0.0 1.5 1 0 0 1 1 1 1 VAD1 Analog of StAR-related lipid transfer domain GRAM PF02893.20 AIN97102.1 - 2.3e-15 56.5 3.8 1.1e-08 35.0 0.5 2.4 2 0 0 2 2 2 2 GRAM domain DNAPolymera_Pol PF11590.8 AIN97102.1 - 0.74 9.8 2.7 0.45 10.5 0.1 1.9 2 0 0 2 2 2 0 DNA polymerase catalytic subunit Pol Mucin15 PF15672.5 AIN97103.1 - 3.4 7.1 8.1 2.3 7.6 6.3 1.5 1 1 0 1 1 1 0 Cell-membrane associated Mucin15 Pkinase PF00069.25 AIN97104.1 - 1.1e-67 228.2 0.0 1.4e-67 227.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 AIN97104.1 - 1.4e-38 132.7 0.0 1.9e-38 132.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase POLO_box PF00659.18 AIN97104.1 - 1e-31 108.9 0.0 4e-17 62.2 0.0 2.6 2 0 0 2 2 2 2 POLO box duplicated region Kinase-like PF14531.6 AIN97104.1 - 1.1e-08 34.7 0.0 1.4e-07 31.1 0.0 2.1 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 AIN97104.1 - 0.00025 20.0 0.1 0.00035 19.5 0.1 1.2 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 AIN97104.1 - 0.00083 18.4 0.2 0.0013 17.8 0.2 1.2 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 AIN97104.1 - 0.0015 18.5 1.4 0.029 14.3 0.0 3.0 2 1 1 3 3 3 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 AIN97104.1 - 0.11 11.5 0.1 0.18 10.8 0.1 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 VID27 PF08553.10 AIN97105.1 - 1.3e-29 103.4 0.0 2.2e-29 102.7 0.0 1.2 1 0 0 1 1 1 1 VID27 C-terminal WD40-like domain Pkinase PF00069.25 AIN97108.1 - 9.9e-24 84.1 0.0 1e-11 44.8 0.0 4.1 4 0 0 4 4 4 4 Protein kinase domain Pkinase_Tyr PF07714.17 AIN97108.1 - 0.0018 17.6 0.0 0.04 13.2 0.0 2.6 3 0 0 3 3 3 1 Protein tyrosine kinase SLATT_2 PF18183.1 AIN97110.1 - 0.0087 15.9 0.0 0.018 14.8 0.0 1.5 1 0 0 1 1 1 1 SMODS and SLOG-associating 2TM effector domain 2 DUF1451 PF07295.11 AIN97110.1 - 0.2 11.7 3.8 0.4 10.7 0.0 2.8 3 0 0 3 3 3 0 Zinc-ribbon containing domain Methyltransf_16 PF10294.9 AIN97111.1 - 6.1e-19 68.4 0.0 1.8e-14 53.9 0.0 2.7 2 1 1 3 3 3 2 Lysine methyltransferase MTS PF05175.14 AIN97111.1 - 0.071 12.7 0.8 0.25 10.9 0.2 2.1 1 1 1 2 2 2 0 Methyltransferase small domain PvlArgDC PF01862.16 AIN97111.1 - 0.15 11.8 0.7 0.47 10.2 0.3 2.0 2 0 0 2 2 2 0 Pyruvoyl-dependent arginine decarboxylase (PvlArgDC) Myb_DNA-binding PF00249.31 AIN97112.1 - 1.3e-19 70.1 4.0 3.2e-11 43.2 0.3 2.6 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 AIN97112.1 - 3.6e-14 52.7 10.7 1.4e-08 34.8 0.3 2.9 2 0 0 2 2 2 2 Myb-like DNA-binding domain DUF4452 PF14618.6 AIN97112.1 - 0.0023 17.8 0.7 0.0023 17.8 0.7 3.4 3 1 0 3 3 3 1 Domain of unknown function (DUF4452) Myb_DNA-bind_4 PF13837.6 AIN97112.1 - 0.038 14.3 4.0 1.4 9.4 0.1 3.6 3 0 0 3 3 3 0 Myb/SANT-like DNA-binding domain IMPDH PF00478.25 AIN97114.1 - 3.2e-145 483.5 5.5 3.6e-145 483.3 5.5 1.0 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain CBS PF00571.28 AIN97114.1 - 7.1e-11 42.4 0.0 0.00058 20.3 0.0 2.7 2 0 0 2 2 2 2 CBS domain NMO PF03060.15 AIN97114.1 - 1.1e-07 31.6 8.2 0.00033 20.2 8.8 2.3 2 0 0 2 2 2 2 Nitronate monooxygenase FMN_dh PF01070.18 AIN97114.1 - 1.5e-06 27.5 12.1 3.5e-06 26.3 12.1 1.7 1 1 0 1 1 1 1 FMN-dependent dehydrogenase His_biosynth PF00977.21 AIN97114.1 - 0.00037 20.0 2.3 0.018 14.5 0.1 2.3 1 1 1 2 2 2 2 Histidine biosynthesis protein ThiG PF05690.14 AIN97114.1 - 0.00063 19.1 5.5 0.0045 16.3 1.0 2.4 2 0 0 2 2 2 1 Thiazole biosynthesis protein ThiG Glu_synthase PF01645.17 AIN97114.1 - 0.00083 18.6 5.3 0.0015 17.7 5.3 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase DHO_dh PF01180.21 AIN97114.1 - 0.0031 16.8 4.6 0.024 13.8 0.7 2.3 2 0 0 2 2 2 1 Dihydroorotate dehydrogenase NanE PF04131.14 AIN97114.1 - 0.1 11.8 3.5 2 7.6 0.2 2.8 2 1 0 2 2 2 0 Putative N-acetylmannosamine-6-phosphate epimerase G3P_antiterm PF04309.12 AIN97114.1 - 0.12 11.8 0.8 0.74 9.2 0.1 2.3 2 0 0 2 2 2 0 Glycerol-3-phosphate responsive antiterminator PcrB PF01884.17 AIN97114.1 - 2.4 7.6 8.1 3.1 7.2 0.1 3.6 3 1 1 4 4 4 0 PcrB family Lysine_decarbox PF03641.14 AIN97115.1 - 1.4e-27 96.4 0.5 2.1e-27 95.8 0.5 1.3 1 0 0 1 1 1 1 Possible lysine decarboxylase LDcluster4 PF18306.1 AIN97115.1 - 3.1e-10 39.9 1.1 4.7e-10 39.3 1.1 1.2 1 0 0 1 1 1 1 SLOG cluster4 family ABM PF03992.16 AIN97115.1 - 1.4e-07 31.6 0.1 3.4e-07 30.3 0.1 1.6 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase LSDAT_prok PF18171.1 AIN97115.1 - 0.032 13.5 0.3 0.063 12.5 0.1 1.5 2 0 0 2 2 2 0 SLOG in TRPM, prokaryote MutL PF13941.6 AIN97115.1 - 0.056 12.0 0.1 0.12 11.0 0.1 1.5 2 0 0 2 2 2 0 MutL protein Baseplate_J PF04865.14 AIN97115.1 - 0.063 12.4 0.2 0.094 11.8 0.2 1.2 1 0 0 1 1 1 0 Baseplate J-like protein Methyltransf_30 PF05430.11 AIN97115.1 - 0.11 12.4 0.0 0.22 11.4 0.0 1.5 1 0 0 1 1 1 0 S-adenosyl-L-methionine-dependent methyltransferase Kinesin PF00225.23 AIN97116.1 - 1.1e-102 343.4 0.1 1.1e-102 343.4 0.1 2.2 2 1 1 3 3 3 1 Kinesin motor domain Microtub_bd PF16796.5 AIN97116.1 - 5.9e-26 91.2 0.0 5.9e-26 91.2 0.0 2.6 3 0 0 3 3 3 1 Microtubule binding Spc42p PF11544.8 AIN97116.1 - 0.0011 18.9 2.9 0.0011 18.9 2.9 5.4 3 1 2 6 6 6 1 Spindle pole body component Spc42p COG5 PF10392.9 AIN97116.1 - 0.016 15.4 3.8 0.016 15.4 3.8 5.1 3 2 2 5 5 5 0 Golgi transport complex subunit 5 DUF4988 PF16378.5 AIN97116.1 - 0.79 9.4 6.6 0.23 11.1 0.6 3.1 2 1 0 2 2 2 0 Domain of unknown function DUF4806 PF16064.5 AIN97116.1 - 0.96 9.8 5.7 0.99 9.7 1.4 3.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4806) eIF-3c_N PF05470.12 AIN97117.1 - 0.038 12.3 0.5 0.055 11.8 0.5 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus G-patch PF01585.23 AIN97118.1 - 2.6e-12 46.4 0.3 6.4e-12 45.2 0.3 1.7 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 AIN97118.1 - 0.00028 20.9 0.5 0.00088 19.3 0.5 1.8 1 0 0 1 1 1 1 G-patch domain S100PBPR PF15427.6 AIN97118.1 - 0.0028 17.0 3.2 0.0035 16.7 3.2 1.1 1 0 0 1 1 1 1 S100P-binding protein Peptidase_S55 PF05580.12 AIN97118.1 - 0.12 12.3 0.0 0.16 11.9 0.0 1.1 1 0 0 1 1 1 0 SpoIVB peptidase S55 Presenilin PF01080.17 AIN97118.1 - 3.2 6.4 5.2 4.1 6.1 5.2 1.1 1 0 0 1 1 1 0 Presenilin DBR1 PF05011.13 AIN97120.1 - 7.3e-09 36.2 0.0 1.3e-08 35.4 0.0 1.4 1 0 0 1 1 1 1 Lariat debranching enzyme, C-terminal domain Metallophos PF00149.28 AIN97120.1 - 1.9e-05 25.3 0.0 4.7e-05 24.0 0.0 1.7 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase ATP-synt_10 PF05176.14 AIN97121.1 - 0.0027 17.0 0.0 0.0081 15.4 0.0 1.8 1 0 0 1 1 1 1 ATP10 protein DUF1935 PF09149.10 AIN97124.1 - 2.1e-34 118.0 0.1 4.1e-34 117.1 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1935) META PF03724.16 AIN97124.1 - 7.6e-26 90.2 0.3 8e-09 35.4 0.0 3.3 3 0 0 3 3 3 3 META domain YabA PF06156.13 AIN97124.1 - 0.082 13.6 0.0 0.7 10.6 0.0 2.3 2 0 0 2 2 2 0 Initiation control protein YabA TipAS PF07739.13 AIN97125.1 - 0.096 13.2 0.0 2.1 8.9 0.0 2.7 2 0 0 2 2 2 0 TipAS antibiotic-recognition domain META PF03724.16 AIN97126.1 - 1.7e-10 40.8 0.0 1.9e-10 40.6 0.0 1.0 1 0 0 1 1 1 1 META domain LRR_6 PF13516.6 AIN97127.1 - 7.3e-12 44.3 1.7 0.081 13.0 0.0 5.7 6 0 0 6 6 6 4 Leucine Rich repeat LRR_4 PF12799.7 AIN97127.1 - 2.1e-06 28.0 5.0 0.22 12.0 0.1 4.6 4 1 2 6 6 6 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 AIN97127.1 - 0.0014 18.9 0.2 80 4.4 0.0 5.2 5 0 0 5 5 5 0 Leucine Rich Repeat LRR_8 PF13855.6 AIN97127.1 - 0.038 13.8 4.7 15 5.5 0.0 4.2 3 3 0 3 3 3 0 Leucine rich repeat DUF3729 PF12526.8 AIN97127.1 - 1.4 10.5 7.2 0.54 11.8 4.0 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3729) Acyltransferase PF01553.21 AIN97128.1 - 4.7e-15 55.4 0.0 8.1e-15 54.6 0.0 1.4 1 0 0 1 1 1 1 Acyltransferase Acyltransf_C PF16076.5 AIN97128.1 - 2.5e-05 24.3 0.1 0.0013 18.7 0.1 2.7 1 1 0 1 1 1 1 Acyltransferase C-terminus Sec63 PF02889.16 AIN97129.1 - 9.6e-52 175.7 0.1 3e-49 167.5 0.0 2.4 2 0 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.29 AIN97129.1 - 4.9e-32 111.1 0.5 1.5e-23 83.5 0.4 3.0 3 0 0 3 3 3 2 DEAD/DEAH box helicase ResIII PF04851.15 AIN97129.1 - 9.1e-11 42.0 0.0 3.1e-09 37.1 0.0 2.3 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_PWI PF18149.1 AIN97129.1 - 3e-08 33.8 0.0 8.7e-08 32.3 0.0 1.8 1 0 0 1 1 1 1 N-terminal helicase PWI domain Helicase_C PF00271.31 AIN97129.1 - 1.5e-07 31.7 0.0 1.1e-06 29.0 0.0 2.4 1 1 0 1 1 1 1 Helicase conserved C-terminal domain AAA_16 PF13191.6 AIN97129.1 - 0.0062 16.9 2.9 4.7 7.6 0.0 3.9 4 0 0 4 4 4 2 AAA ATPase domain AAA_19 PF13245.6 AIN97129.1 - 0.43 10.9 3.5 1.6 9.1 0.9 3.1 3 0 0 3 3 3 0 AAA domain FH2 PF02181.23 AIN97130.1 - 1.2e-46 159.5 0.0 1.9e-46 158.9 0.0 1.2 1 0 0 1 1 1 1 Formin Homology 2 Domain CUE PF02845.16 AIN97130.1 - 0.0019 17.8 0.0 0.0098 15.6 0.0 2.2 2 0 0 2 2 2 1 CUE domain Med9 PF07544.13 AIN97130.1 - 0.0031 17.5 0.2 0.01 15.9 0.2 1.8 1 0 0 1 1 1 1 RNA polymerase II transcription mediator complex subunit 9 RPW8 PF05659.11 AIN97130.1 - 0.081 12.6 0.6 0.27 10.9 0.3 1.9 1 1 1 2 2 2 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 PCIF1_WW PF12237.8 AIN97131.1 - 4.7e-34 117.5 0.1 1.1e-32 113.0 0.1 2.7 2 1 0 2 2 2 1 Phosphorylated CTD interacting factor 1 WW domain PDEase_I PF00233.19 AIN97132.1 - 3.9e-14 53.0 0.0 8.1e-14 51.9 0.0 1.5 1 1 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase Mak10 PF04112.13 AIN97133.1 - 1e-05 25.1 0.1 0.00036 20.1 0.1 2.5 1 1 0 1 1 1 1 Mak10 subunit, NatC N(alpha)-terminal acetyltransferase DUF826 PF05696.11 AIN97133.1 - 0.11 12.6 0.5 0.43 10.7 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF826) GGA_N-GAT PF18308.1 AIN97133.1 - 0.21 11.3 2.6 14 5.4 0.3 2.6 2 0 0 2 2 2 0 GGA N-GAT domain PI3_PI4_kinase PF00454.27 AIN97134.1 - 0.0013 18.6 0.0 0.0025 17.7 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase HEAT PF02985.22 AIN97134.1 - 0.12 12.7 2.1 16 6.1 0.1 4.2 2 0 0 2 2 2 0 HEAT repeat Abhydrolase_1 PF00561.20 AIN97136.1 - 2.2e-24 86.5 0.1 1.8e-17 63.9 0.1 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 AIN97136.1 - 8.6e-14 51.4 0.1 8.5e-13 48.1 0.1 2.0 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 AIN97136.1 - 3.7e-06 27.7 0.2 5.5e-06 27.2 0.2 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 AIN97136.1 - 3e-05 23.6 0.1 0.021 14.3 0.0 2.6 3 0 0 3 3 3 2 Prolyl oligopeptidase family FSH1 PF03959.13 AIN97136.1 - 0.00011 21.9 0.1 0.00028 20.6 0.1 1.6 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Esterase PF00756.20 AIN97136.1 - 0.00015 21.5 0.1 0.00026 20.7 0.1 1.4 1 1 0 1 1 1 1 Putative esterase PGAP1 PF07819.13 AIN97136.1 - 0.00048 19.9 0.3 0.0015 18.3 0.3 1.7 2 0 0 2 2 2 1 PGAP1-like protein Abhydrolase_4 PF08386.10 AIN97136.1 - 0.00091 19.3 0.0 0.0026 17.9 0.0 1.7 1 0 0 1 1 1 1 TAP-like protein Abhydrolase_2 PF02230.16 AIN97136.1 - 0.0012 18.7 0.0 0.08 12.7 0.0 2.2 2 0 0 2 2 2 1 Phospholipase/Carboxylesterase Esterase_phd PF10503.9 AIN97136.1 - 0.0027 17.2 0.0 1.6 8.1 0.0 2.3 1 1 0 2 2 2 2 Esterase PHB depolymerase Ndr PF03096.14 AIN97136.1 - 0.0039 15.9 0.0 0.0053 15.5 0.0 1.3 1 0 0 1 1 1 1 Ndr family DLH PF01738.18 AIN97136.1 - 0.094 12.3 0.0 4.3 6.8 0.0 2.7 2 2 0 2 2 2 0 Dienelactone hydrolase family GlcNAc PF11397.8 AIN97137.1 - 3.4e-153 510.2 0.0 4.2e-153 509.9 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase (GlcNAc) DUF2721 PF11026.8 AIN97137.1 - 0.0053 16.6 0.2 0.01 15.7 0.2 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2721) DUF2452 PF10504.9 AIN97137.1 - 0.19 11.2 0.0 0.34 10.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2452) Abhydrolase_1 PF00561.20 AIN97139.1 - 1.4e-17 64.2 0.0 3e-17 63.1 0.0 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 AIN97139.1 - 5.1e-09 37.1 0.6 1.8e-08 35.2 0.6 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 AIN97139.1 - 1.9e-08 33.9 1.0 0.0038 16.5 0.7 2.8 2 1 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_4 PF08386.10 AIN97139.1 - 2.2e-05 24.5 0.0 5e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 TAP-like protein Esterase_phd PF10503.9 AIN97139.1 - 0.022 14.2 0.1 0.43 10.0 0.0 2.2 2 0 0 2 2 2 0 Esterase PHB depolymerase Peptidase_S9 PF00326.21 AIN97139.1 - 0.027 13.9 0.0 2.6 7.4 0.0 2.2 2 0 0 2 2 2 0 Prolyl oligopeptidase family Ser_hydrolase PF06821.13 AIN97139.1 - 0.037 13.9 0.1 0.11 12.4 0.0 1.7 2 0 0 2 2 2 0 Serine hydrolase Ndr PF03096.14 AIN97139.1 - 0.06 12.0 0.0 0.089 11.5 0.0 1.3 1 0 0 1 1 1 0 Ndr family PGAP1 PF07819.13 AIN97139.1 - 0.087 12.5 0.1 0.13 11.9 0.1 1.2 1 0 0 1 1 1 0 PGAP1-like protein Esterase PF00756.20 AIN97139.1 - 0.09 12.4 0.0 0.16 11.5 0.0 1.4 1 0 0 1 1 1 0 Putative esterase Abhydrolase_1 PF00561.20 AIN97140.1 - 6.9e-22 78.3 0.0 1.9e-21 76.9 0.0 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 AIN97140.1 - 1.3e-15 57.3 0.0 2.5e-15 56.4 0.0 1.4 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 AIN97140.1 - 1.3e-11 45.6 1.0 1.9e-11 45.0 1.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.20 AIN97140.1 - 5.9e-05 22.8 0.0 0.00027 20.7 0.1 1.9 2 0 0 2 2 2 1 Putative esterase Abhydrolase_4 PF08386.10 AIN97140.1 - 0.0013 18.8 0.0 0.0025 17.9 0.0 1.4 1 0 0 1 1 1 1 TAP-like protein Esterase_phd PF10503.9 AIN97140.1 - 0.0016 18.0 0.2 0.093 12.2 0.0 2.2 2 0 0 2 2 2 1 Esterase PHB depolymerase Abhydrolase_2 PF02230.16 AIN97140.1 - 0.0018 18.2 0.0 0.16 11.7 0.0 2.2 2 0 0 2 2 2 1 Phospholipase/Carboxylesterase Ndr PF03096.14 AIN97140.1 - 0.0057 15.4 0.0 0.015 14.1 0.0 1.6 2 0 0 2 2 2 1 Ndr family Thioesterase PF00975.20 AIN97140.1 - 0.044 13.9 0.1 0.081 13.0 0.1 1.3 1 0 0 1 1 1 0 Thioesterase domain DLH PF01738.18 AIN97140.1 - 0.056 13.0 0.0 0.35 10.4 0.0 1.9 2 0 0 2 2 2 0 Dienelactone hydrolase family FIST PF08495.10 AIN97140.1 - 0.11 12.6 0.0 0.22 11.5 0.0 1.6 1 0 0 1 1 1 0 FIST N domain Ser_hydrolase PF06821.13 AIN97140.1 - 0.21 11.4 0.3 0.36 10.7 0.0 1.5 2 0 0 2 2 2 0 Serine hydrolase Abhydrolase_1 PF00561.20 AIN97141.1 - 1.3e-18 67.5 0.0 1.3e-17 64.3 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 AIN97141.1 - 1.4e-11 44.1 0.0 6.7e-11 41.9 0.0 2.0 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 AIN97141.1 - 3.3e-08 34.4 3.4 8.8e-08 33.0 3.4 1.7 1 0 0 1 1 1 1 Alpha/beta hydrolase family Thioesterase PF00975.20 AIN97141.1 - 0.0013 18.9 0.0 0.0023 18.1 0.0 1.3 1 0 0 1 1 1 1 Thioesterase domain Abhydrolase_4 PF08386.10 AIN97141.1 - 0.0088 16.2 0.0 0.036 14.2 0.0 2.0 2 0 0 2 2 2 1 TAP-like protein Ndr PF03096.14 AIN97141.1 - 0.17 10.5 0.0 0.33 9.6 0.0 1.3 1 0 0 1 1 1 0 Ndr family PLAC8 PF04749.17 AIN97142.1 - 0.26 12.3 17.6 0.38 11.8 15.5 2.2 2 1 0 2 2 2 0 PLAC8 family UCH PF00443.29 AIN97144.1 - 1.8e-20 73.5 0.0 4.6e-20 72.2 0.0 1.6 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 AIN97144.1 - 2.5e-06 27.3 0.0 9.4e-06 25.4 0.0 1.7 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Rubredoxin_2 PF18073.1 AIN97144.1 - 2.4 8.0 5.1 5.4 6.8 5.1 1.6 1 0 0 1 1 1 0 Rubredoxin metal binding domain Steroid_dh PF02544.16 AIN97145.1 - 2.6e-24 85.9 2.7 1.3e-09 38.2 0.0 4.4 4 0 0 4 4 4 4 3-oxo-5-alpha-steroid 4-dehydrogenase Kinesin PF00225.23 AIN97146.1 - 6e-86 288.4 0.1 1.1e-85 287.6 0.1 1.4 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 AIN97146.1 - 6.2e-23 81.4 0.0 1.3e-22 80.3 0.0 1.5 1 0 0 1 1 1 1 Microtubule binding Calpain_III PF01067.22 AIN97146.1 - 3.1e-13 50.2 0.0 2.5e-10 40.8 0.0 2.7 2 0 0 2 2 2 2 Calpain large subunit, domain III Arm PF00514.23 AIN97146.1 - 1.6e-06 28.0 6.5 0.31 11.2 0.1 6.0 7 1 1 8 8 8 3 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.6 AIN97146.1 - 0.052 13.9 0.3 1.1 9.7 0.1 2.9 1 1 2 3 3 3 0 HEAT repeats HEAT_EZ PF13513.6 AIN97146.1 - 0.16 12.5 1.5 0.58 10.7 0.1 2.9 2 1 1 3 3 3 0 HEAT-like repeat Methyltr_RsmB-F PF01189.17 AIN97148.1 - 6.3e-28 97.8 0.0 4.6e-17 62.3 0.0 4.1 5 0 0 5 5 5 3 16S rRNA methyltransferase RsmB/F WW PF00397.26 AIN97149.1 - 5.7e-09 35.9 0.1 1.1e-08 35.0 0.1 1.5 1 0 0 1 1 1 1 WW domain XRN_N PF03159.18 AIN97150.1 - 2.7e-70 236.6 0.0 4.1e-70 236.0 0.0 1.3 1 0 0 1 1 1 1 XRN 5'-3' exonuclease N-terminus XRN_M PF17846.1 AIN97150.1 - 1.2e-36 126.7 0.0 6.2e-20 71.6 0.0 2.1 1 1 1 2 2 2 2 Xrn1 helical domain zf-RanBP PF00641.18 AIN97150.1 - 0.00012 21.3 6.4 0.00032 19.9 6.4 1.7 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others UDPGP PF01704.18 AIN97151.1 - 8.1e-10 37.9 0.0 2.1e-09 36.5 0.0 1.5 2 0 0 2 2 2 1 UTP--glucose-1-phosphate uridylyltransferase DUF4375 PF14300.6 AIN97151.1 - 0.14 12.5 0.0 0.26 11.5 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4375) DUF1843 PF08898.10 AIN97153.1 - 0.59 10.7 8.2 38 4.9 0.0 4.4 3 1 1 4 4 4 0 Domain of unknown function (DUF1843) PRIMA1 PF16101.5 AIN97153.1 - 2.4 8.2 8.2 12 5.9 1.3 2.9 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 Lebercilin PF15619.6 AIN97153.1 - 2.4 7.8 9.8 1.6 8.4 3.0 2.3 2 0 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease TMF_TATA_bd PF12325.8 AIN97153.1 - 4.3 7.6 7.8 7.3 6.8 2.7 2.5 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding PKcGMP_CC PF16808.5 AIN97155.1 - 0.03 14.2 1.4 0.067 13.0 1.4 1.5 1 0 0 1 1 1 0 Coiled-coil N-terminus of cGMP-dependent protein kinase ATG16 PF08614.11 AIN97155.1 - 0.032 14.4 0.8 0.032 14.4 0.8 3.5 2 1 1 3 3 3 0 Autophagy protein 16 (ATG16) ADIP PF11559.8 AIN97155.1 - 0.062 13.4 4.7 0.11 12.6 0.3 2.4 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding Fez1 PF06818.15 AIN97155.1 - 0.11 12.9 0.3 0.27 11.7 0.3 1.6 1 0 0 1 1 1 0 Fez1 SlyX PF04102.12 AIN97155.1 - 0.23 12.1 3.3 2.4 8.8 0.0 2.6 2 0 0 2 2 2 0 SlyX DUF4407 PF14362.6 AIN97155.1 - 0.23 10.7 1.9 0.47 9.8 1.9 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) MAD PF05557.13 AIN97155.1 - 0.61 8.4 4.0 1.9 6.8 0.6 2.0 2 0 0 2 2 2 0 Mitotic checkpoint protein TolA_bind_tri PF16331.5 AIN97155.1 - 0.78 9.9 7.4 0.26 11.4 1.5 2.5 2 0 0 2 2 2 0 TolA binding protein trimerisation TRAF_BIRC3_bd PF16673.5 AIN97155.1 - 1.1 9.1 3.8 0.85 9.4 0.3 2.3 2 0 0 2 2 2 0 TNF receptor-associated factor BIRC3 binding domain BRE1 PF08647.11 AIN97155.1 - 1.8 8.7 5.1 0.56 10.3 0.3 2.2 2 0 0 2 2 2 0 BRE1 E3 ubiquitin ligase ZapB PF06005.12 AIN97155.1 - 2 8.9 4.6 0.68 10.4 0.2 2.3 2 0 0 2 2 2 0 Cell division protein ZapB HAP1_N PF04849.13 AIN97155.1 - 2.2 7.4 6.1 0.51 9.5 1.1 2.0 2 0 0 2 2 2 0 HAP1 N-terminal conserved region ERM PF00769.19 AIN97155.1 - 2.5 7.8 7.9 13 5.5 1.8 2.5 2 0 0 2 2 2 0 Ezrin/radixin/moesin family FlaC_arch PF05377.11 AIN97155.1 - 5.6 7.4 8.0 13 6.2 1.5 2.3 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) CLZ PF16526.5 AIN97155.1 - 6.3 7.2 6.8 16 6.0 0.9 2.6 2 1 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels DivIC PF04977.15 AIN97155.1 - 6.8 6.5 5.9 1.6 8.6 0.6 2.2 2 0 0 2 2 2 0 Septum formation initiator Motile_Sperm PF00635.26 AIN97156.1 - 8.9e-11 41.6 0.0 1.8e-10 40.6 0.0 1.6 1 0 0 1 1 1 1 MSP (Major sperm protein) domain TPR_2 PF07719.17 AIN97158.1 - 6.5e-12 44.6 6.5 0.00059 19.7 0.0 6.1 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_17 PF13431.6 AIN97158.1 - 1.8e-08 34.1 0.0 0.023 15.1 0.0 4.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 AIN97158.1 - 8e-08 31.9 0.0 0.02 15.1 0.0 4.8 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_1 PF00515.28 AIN97158.1 - 1.2e-06 28.1 0.3 0.069 13.0 0.0 3.9 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.6 AIN97158.1 - 1.4e-06 28.6 30.6 0.22 12.5 0.0 9.7 7 2 3 10 10 9 4 Tetratricopeptide repeat TPR_16 PF13432.6 AIN97158.1 - 0.0024 18.5 15.9 0.0065 17.1 0.1 5.9 7 0 0 7 7 6 2 Tetratricopeptide repeat TPR_11 PF13414.6 AIN97158.1 - 0.011 15.4 0.0 0.13 11.9 0.0 2.8 2 0 0 2 2 2 0 TPR repeat TPR_7 PF13176.6 AIN97158.1 - 0.015 15.3 3.3 14 6.0 0.0 5.2 4 1 0 4 4 4 0 Tetratricopeptide repeat Clathrin PF00637.20 AIN97158.1 - 0.056 13.3 0.3 0.22 11.4 0.1 2.0 2 0 0 2 2 2 0 Region in Clathrin and VPS TPR_9 PF13371.6 AIN97158.1 - 0.059 13.5 2.4 1.5 9.0 0.0 4.6 5 1 1 6 6 6 0 Tetratricopeptide repeat TPR_12 PF13424.6 AIN97158.1 - 1.9 8.8 0.0 1.9 8.8 0.0 6.3 7 0 0 7 7 7 0 Tetratricopeptide repeat GNAT_acetyltr_2 PF13718.6 AIN97159.1 - 8.5e-81 270.7 0.0 1.7e-80 269.6 0.0 1.5 1 0 0 1 1 1 1 GNAT acetyltransferase 2 Helicase_RecD PF05127.14 AIN97159.1 - 1.6e-59 200.7 0.0 4e-59 199.4 0.0 1.7 1 0 0 1 1 1 1 Helicase DUF1726 PF08351.11 AIN97159.1 - 4.8e-30 103.3 0.0 1.5e-29 101.8 0.0 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF1726) tRNA_bind_2 PF13725.6 AIN97159.1 - 1.2e-23 84.0 0.0 5.6e-23 81.9 0.0 1.9 1 1 0 1 1 1 1 Possible tRNA binding domain AAA_30 PF13604.6 AIN97159.1 - 4.4e-05 23.3 0.1 0.00064 19.5 0.1 2.6 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 AIN97159.1 - 0.00066 20.0 0.3 0.007 16.7 0.0 2.4 2 0 0 2 2 2 1 AAA domain DUF5585 PF17823.1 AIN97159.1 - 0.17 10.8 1.8 0.31 9.9 1.8 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5585) Oscp1 PF10188.9 AIN97160.1 - 1.7e-55 187.9 0.0 2.2e-55 187.5 0.0 1.1 1 0 0 1 1 1 1 Organic solute transport protein 1 eIF2A PF08662.11 AIN97163.1 - 1.2e-12 48.1 0.0 3.1e-12 46.8 0.0 1.7 1 0 0 1 1 1 1 Eukaryotic translation initiation factor eIF2A Methyltransf_32 PF13679.6 AIN97165.1 - 8.9e-12 45.3 2.8 6.7e-06 26.2 0.2 3.0 2 1 0 2 2 2 2 Methyltransferase domain TRM13 PF05206.14 AIN97165.1 - 0.031 13.8 0.0 0.12 11.8 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase TRM13 DUF2362 PF10154.9 AIN97165.1 - 0.1 11.5 0.1 0.16 10.9 0.1 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2362) CTP_transf_like PF01467.26 AIN97168.1 - 6.6e-18 65.3 0.0 8.6e-18 64.9 0.0 1.2 1 0 0 1 1 1 1 Cytidylyltransferase-like Cyt-b5 PF00173.28 AIN97169.1 - 1.7e-15 56.9 0.0 2.7e-15 56.3 0.0 1.3 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain ALO PF04030.14 AIN97170.1 - 2.5e-60 204.5 2.4 8.1e-56 189.7 0.3 2.2 2 0 0 2 2 2 2 D-arabinono-1,4-lactone oxidase FAD_binding_4 PF01565.23 AIN97170.1 - 6.3e-22 77.8 0.1 1e-21 77.1 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain SDA1 PF05285.12 AIN97171.1 - 5.3e-76 256.3 40.3 5.3e-76 256.3 40.3 2.5 2 1 0 2 2 2 1 SDA1 NUC130_3NT PF08158.12 AIN97171.1 - 1.5e-12 47.6 0.0 4.9e-12 46.0 0.0 2.0 1 0 0 1 1 1 1 NUC130/3NT domain DUF1828 PF08861.10 AIN97171.1 - 0.26 11.6 3.3 1.1 9.6 0.1 2.8 2 1 1 3 3 3 0 Domain of unknown function DUF1828 IQ PF00612.27 AIN97173.1 - 4.9e-09 35.2 40.9 0.015 15.0 0.6 6.8 6 1 0 6 6 6 5 IQ calmodulin-binding motif Inositol_P PF00459.25 AIN97174.1 - 7.1e-51 173.3 0.5 9.1e-51 173.0 0.5 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family Peptidase_C65 PF10275.9 AIN97175.1 - 3.3e-62 210.1 0.2 3.8e-62 209.9 0.2 1.0 1 0 0 1 1 1 1 Peptidase C65 Otubain OTU PF02338.19 AIN97175.1 - 0.00031 21.2 0.2 0.0084 16.6 0.2 2.4 2 1 0 2 2 2 1 OTU-like cysteine protease zf-UDP PF14569.6 AIN97175.1 - 0.17 12.0 0.5 0.66 10.1 0.1 2.0 2 0 0 2 2 2 0 Zinc-binding RING-finger zf-ZPR1 PF03367.13 AIN97176.1 - 3.4e-108 358.5 0.2 5e-55 185.7 0.1 2.1 2 0 0 2 2 2 2 ZPR1 zinc-finger domain HypA PF01155.19 AIN97176.1 - 0.00074 19.5 2.5 0.91 9.6 0.3 2.5 2 0 0 2 2 2 2 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DnaJ_CXXCXGXG PF00684.19 AIN97176.1 - 0.092 13.1 8.0 0.6 10.5 0.8 2.7 2 1 0 2 2 2 0 DnaJ central domain zf-RRPl_C4 PF17026.5 AIN97176.1 - 1.5 9.0 6.5 0.36 11.0 0.1 2.8 2 1 1 3 3 3 0 Putative ribonucleoprotein zinc-finger pf C4 type DiS_P_DiS PF06750.13 AIN97176.1 - 3.1 8.0 5.6 28 4.9 0.1 3.1 2 1 1 3 3 3 0 Bacterial Peptidase A24 N-terminal domain DUF2387 PF09526.10 AIN97176.1 - 3.3 7.9 6.7 16 5.7 0.6 2.8 2 1 0 2 2 2 0 Probable metal-binding protein (DUF2387) zinc-ribbons_6 PF07191.12 AIN97176.1 - 3.6 7.6 9.1 1.4 8.9 0.3 3.0 3 0 0 3 3 3 0 zinc-ribbons Anti-TRAP PF15777.5 AIN97176.1 - 4.8 7.2 8.3 1.9 8.5 0.9 3.4 3 1 0 3 3 3 0 Tryptophan RNA-binding attenuator protein inhibitory protein MFS_1 PF07690.16 AIN97178.1 - 1.3e-19 70.3 39.9 1.3e-19 70.3 39.9 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily zf-LITAF-like PF10601.9 AIN97178.1 - 0.87 9.9 2.6 5.2 7.4 0.1 3.4 2 1 1 3 3 3 0 LITAF-like zinc ribbon domain Ion_trans PF00520.31 AIN97179.1 - 1.9e-09 37.1 11.8 6e-07 29.0 9.5 2.1 2 0 0 2 2 2 2 Ion transport protein RabGAP-TBC PF00566.18 AIN97180.1 - 1.7e-18 67.1 0.1 2.8e-18 66.4 0.1 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Ferrochelatase PF00762.19 AIN97181.1 - 6.9e-66 222.5 0.0 4.8e-50 170.4 0.0 2.1 2 0 0 2 2 2 2 Ferrochelatase PPR_2 PF13041.6 AIN97183.1 - 4.5e-48 161.2 7.1 2.5e-08 34.0 0.0 12.2 9 4 5 14 14 14 8 PPR repeat family PPR PF01535.20 AIN97183.1 - 6.5e-42 138.9 15.4 0.0025 18.0 0.0 17.0 18 0 0 18 18 18 10 PPR repeat PPR_3 PF13812.6 AIN97183.1 - 1e-24 86.3 0.4 6.2e-05 23.0 0.0 9.0 8 1 0 9 9 9 5 Pentatricopeptide repeat domain PPR_1 PF12854.7 AIN97183.1 - 1.1e-15 57.0 12.7 0.043 13.5 0.0 12.0 14 0 0 14 14 14 4 PPR repeat PPR_long PF17177.4 AIN97183.1 - 7.4e-12 45.1 0.1 0.041 13.3 0.0 5.1 3 1 2 5 5 5 4 Pentacotripeptide-repeat region of PRORP ERAP1_C PF11838.8 AIN97183.1 - 2.6e-06 27.2 2.4 0.059 12.9 0.1 4.5 3 1 0 3 3 3 2 ERAP1-like C-terminal domain TPR_14 PF13428.6 AIN97183.1 - 0.0002 21.9 7.1 4.6 8.3 0.2 6.0 4 2 1 5 5 5 2 Tetratricopeptide repeat SPOB_a PF14689.6 AIN97183.1 - 0.0011 18.6 1.5 4.2 7.2 0.1 5.4 5 1 1 6 6 6 1 Sensor_kinase_SpoOB-type, alpha-helical domain ATP13 PF12921.7 AIN97183.1 - 0.0057 16.5 0.0 24 4.8 0.0 5.1 4 2 1 5 5 5 0 Mitochondrial ATPase expression ECSIT PF06239.11 AIN97183.1 - 0.058 12.5 0.1 8 5.5 0.0 3.7 2 1 0 2 2 2 0 Evolutionarily conserved signalling intermediate in Toll pathway TPR_12 PF13424.6 AIN97183.1 - 0.11 12.7 6.2 1 9.7 0.4 4.3 4 1 0 4 4 4 0 Tetratricopeptide repeat RNA_pol_Rpb4 PF03874.16 AIN97183.1 - 0.12 12.7 0.0 46 4.4 0.0 3.8 4 0 0 4 4 3 0 RNA polymerase Rpb4 TPR_19 PF14559.6 AIN97183.1 - 7.9 7.1 11.4 83 3.8 0.0 5.4 5 1 1 6 6 6 0 Tetratricopeptide repeat MDD_C PF18376.1 AIN97184.1 - 1e-53 181.9 0.1 1.8e-53 181.0 0.1 1.4 2 0 0 2 2 2 1 Mevalonate 5-diphosphate decarboxylase C-terminal domain GHMP_kinases_N PF00288.26 AIN97184.1 - 9.1e-05 22.6 6.7 0.00015 21.9 5.2 2.1 2 0 0 2 2 2 1 GHMP kinases N terminal domain DUF1819 PF08849.11 AIN97184.1 - 0.18 11.6 0.0 0.34 10.7 0.0 1.4 1 0 0 1 1 1 0 Putative inner membrane protein (DUF1819) RRM_1 PF00076.22 AIN97185.1 - 9e-05 22.2 0.0 0.00014 21.6 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-C2HC_2 PF13913.6 AIN97188.1 - 2e-36 123.2 62.4 5.3e-09 35.8 1.8 8.4 9 0 0 9 9 9 6 zinc-finger of a C2HC-type DZR PF12773.7 AIN97188.1 - 3.3e-14 52.6 61.4 1.7e-10 40.7 12.4 8.6 6 1 1 7 7 7 3 Double zinc ribbon zf-ribbon_3 PF13248.6 AIN97188.1 - 0.0067 15.8 1.8 0.0067 15.8 1.8 10.0 9 1 3 12 12 12 5 zinc-ribbon domain zinc_ribbon_2 PF13240.6 AIN97188.1 - 0.016 14.9 59.3 0.34 10.7 2.6 9.5 9 0 0 9 9 9 0 zinc-ribbon domain zf-FPG_IleRS PF06827.14 AIN97188.1 - 0.03 14.2 1.3 0.03 14.2 1.3 9.5 10 1 0 10 10 10 0 Zinc finger found in FPG and IleRS NOB1_Zn_bind PF08772.11 AIN97188.1 - 0.037 14.2 1.0 0.037 14.2 1.0 6.5 6 1 1 7 7 7 0 Nin one binding (NOB1) Zn-ribbon like zinc-ribbons_6 PF07191.12 AIN97188.1 - 0.038 14.0 1.0 0.03 14.3 6.3 8.3 10 0 0 10 10 10 0 zinc-ribbons zinc_ribbon_15 PF17032.5 AIN97188.1 - 0.27 12.0 48.6 0.53 11.1 0.3 7.7 8 1 1 9 9 9 0 zinc-ribbon family 3Beta_HSD PF01073.19 AIN97189.1 - 4.6e-10 39.0 0.0 6.6e-10 38.4 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 AIN97189.1 - 5.3e-06 26.5 0.0 9.4e-06 25.6 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 AIN97189.1 - 0.00019 21.0 0.1 0.00045 19.8 0.1 1.6 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 AIN97189.1 - 0.00073 18.7 0.0 0.19 10.8 0.0 3.0 2 1 0 2 2 2 2 RmlD substrate binding domain Semialdhyde_dh PF01118.24 AIN97189.1 - 0.0043 17.5 0.0 0.0092 16.4 0.0 1.6 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain NmrA PF05368.13 AIN97189.1 - 0.007 15.9 0.0 0.011 15.3 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family Glyco_hydro_31 PF01055.26 AIN97190.1 - 1.8e-138 462.5 7.1 2.1e-138 462.2 7.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.6 AIN97190.1 - 1.2e-17 64.0 0.3 8.7e-16 58.0 0.1 2.8 2 0 0 2 2 2 1 Galactose mutarotase-like DUF5110 PF17137.4 AIN97190.1 - 1.3e-06 28.6 0.4 3.9e-06 27.0 0.4 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF5110) OFeT_1 PF16955.5 AIN97191.1 - 0.22 11.2 0.0 0.39 10.4 0.0 1.3 1 0 0 1 1 1 0 Ferrous iron uptake permease, iron-lead transporter DUF726 PF05277.12 AIN97192.1 - 2.3e-59 201.1 25.0 2.4e-56 191.1 0.0 3.2 2 1 1 3 3 3 3 Protein of unknown function (DUF726) VirJ PF06057.11 AIN97192.1 - 0.0019 18.1 0.0 2.7 7.9 0.0 2.3 2 0 0 2 2 2 2 Bacterial virulence protein (VirJ) DUF3089 PF11288.8 AIN97192.1 - 0.055 13.0 0.1 0.37 10.3 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3089) Zwilch PF09817.9 AIN97193.1 - 0.051 12.0 0.0 0.058 11.8 0.0 1.1 1 0 0 1 1 1 0 RZZ complex, subunit zwilch DUF21 PF01595.20 AIN97194.1 - 1.8e-28 99.4 0.1 3.3e-28 98.6 0.1 1.4 1 0 0 1 1 1 1 Cyclin M transmembrane N-terminal domain CBS PF00571.28 AIN97194.1 - 2.1e-07 31.3 0.7 0.0014 19.0 0.1 3.8 4 0 0 4 4 4 2 CBS domain cNMP_binding PF00027.29 AIN97194.1 - 0.0015 18.5 0.0 0.0044 17.0 0.0 1.7 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain DUF21 PF01595.20 AIN97195.1 - 1.6e-40 138.7 0.1 2.9e-40 137.8 0.1 1.4 1 0 0 1 1 1 1 Cyclin M transmembrane N-terminal domain cNMP_binding PF00027.29 AIN97195.1 - 0.0091 16.0 0.0 0.026 14.6 0.0 1.7 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain CBS PF00571.28 AIN97195.1 - 0.12 12.8 0.6 16 6.0 0.0 3.2 3 0 0 3 3 3 0 CBS domain Metallophos PF00149.28 AIN97196.1 - 1.5e-29 103.9 0.2 2.4e-29 103.3 0.2 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase PPP5 PF08321.12 AIN97196.1 - 1.3e-20 73.5 0.4 3e-20 72.3 0.2 1.8 2 0 0 2 2 2 1 PPP5 TPR repeat region TPR_1 PF00515.28 AIN97196.1 - 3.5e-15 55.1 1.0 5.1e-05 22.9 0.1 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 AIN97196.1 - 6.5e-13 47.7 2.9 0.0014 18.6 0.1 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_8 PF13181.6 AIN97196.1 - 1.3e-07 31.2 0.5 0.31 11.4 0.0 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.6 AIN97196.1 - 5.4e-07 29.2 0.4 0.017 14.8 0.0 2.8 2 0 0 2 2 2 2 TPR repeat TPR_17 PF13431.6 AIN97196.1 - 0.0001 22.4 0.1 0.0025 18.1 0.0 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 AIN97196.1 - 0.00014 22.4 2.0 0.065 14.1 0.1 3.4 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 AIN97196.1 - 0.00045 20.7 1.0 0.00091 19.7 1.0 1.5 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_16 PF13432.6 AIN97196.1 - 0.0005 20.7 2.9 0.025 15.2 2.2 2.4 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_9 PF13371.6 AIN97196.1 - 0.0015 18.6 0.4 0.046 13.9 0.1 2.3 1 1 1 2 2 2 2 Tetratricopeptide repeat Paf67 PF10255.9 AIN97196.1 - 0.035 13.1 0.0 0.05 12.6 0.0 1.1 1 0 0 1 1 1 0 RNA polymerase I-associated factor PAF67 TPR_12 PF13424.6 AIN97196.1 - 0.048 13.9 2.6 2.9 8.2 0.4 2.9 1 1 1 2 2 2 0 Tetratricopeptide repeat Lipase_3 PF01764.25 AIN97197.1 - 7.2e-12 45.4 0.0 1.3e-11 44.6 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.7 AIN97197.1 - 0.00057 20.5 0.7 0.0023 18.6 0.2 2.1 2 1 0 2 2 2 1 Alpha/beta hydrolase family RRM_1 PF00076.22 AIN97198.1 - 6.7e-29 99.5 0.0 2.7e-16 59.1 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 AIN97198.1 - 0.0037 16.8 0.0 0.062 12.9 0.0 2.2 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 AIN97198.1 - 0.0043 17.0 0.0 1.6 8.8 0.0 2.5 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif RRM_7 PF16367.5 AIN97198.1 - 0.0044 17.1 0.0 0.54 10.4 0.0 2.5 2 0 0 2 2 2 1 RNA recognition motif Limkain-b1 PF11608.8 AIN97198.1 - 0.079 13.0 0.2 8.3 6.6 0.0 3.0 2 1 1 3 3 3 0 Limkain b1 PHM7_cyt PF14703.6 AIN97198.1 - 0.2 11.9 0.5 43 4.3 0.0 3.0 2 1 1 3 3 3 0 Cytosolic domain of 10TM putative phosphate transporter RRM_1 PF00076.22 AIN97199.1 - 2.2e-30 104.3 0.0 3.4e-17 62.0 0.1 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 AIN97199.1 - 0.0048 17.0 0.0 0.022 14.8 0.0 2.0 2 0 0 2 2 2 1 RNA recognition motif Nup35_RRM_2 PF14605.6 AIN97199.1 - 0.0087 16.0 0.0 2.3 8.3 0.0 2.4 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif SET_assoc PF11767.8 AIN97199.1 - 0.052 13.2 0.2 1.7 8.4 0.0 2.3 2 0 0 2 2 2 0 Histone lysine methyltransferase SET associated Amino_oxidase PF01593.24 AIN97200.1 - 3.7e-12 46.3 0.1 1.2e-11 44.7 0.1 1.9 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 AIN97200.1 - 2.3e-08 34.1 0.9 6.1e-08 32.8 0.1 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 AIN97200.1 - 0.0058 16.6 0.0 0.02 14.9 0.0 2.0 1 0 0 1 1 1 1 FAD-NAD(P)-binding Thi4 PF01946.17 AIN97200.1 - 0.011 15.0 0.1 0.019 14.2 0.1 1.4 1 0 0 1 1 1 0 Thi4 family HhH-GPD PF00730.25 AIN97200.1 - 0.02 15.3 0.0 0.036 14.5 0.0 1.4 1 0 0 1 1 1 0 HhH-GPD superfamily base excision DNA repair protein DAO PF01266.24 AIN97200.1 - 0.029 13.9 0.0 0.061 12.9 0.0 1.6 2 0 0 2 2 2 0 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 AIN97200.1 - 0.03 13.6 0.1 0.077 12.2 0.0 1.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 AIN97200.1 - 0.048 12.9 0.1 0.082 12.2 0.1 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase MCRA PF06100.11 AIN97200.1 - 0.12 11.1 0.0 0.17 10.7 0.0 1.1 1 0 0 1 1 1 0 MCRA family HI0933_like PF03486.14 AIN97200.1 - 0.24 10.1 0.1 0.37 9.4 0.1 1.2 1 0 0 1 1 1 0 HI0933-like protein Aha1_N PF09229.11 AIN97201.1 - 1.9e-25 89.7 0.1 2.7e-25 89.1 0.1 1.2 1 0 0 1 1 1 1 Activator of Hsp90 ATPase, N-terminal AHSA1 PF08327.11 AIN97201.1 - 2.8e-18 66.3 0.0 8.3e-18 64.8 0.0 1.8 2 0 0 2 2 2 1 Activator of Hsp90 ATPase homolog 1-like protein RRM_1 PF00076.22 AIN97202.1 - 1.1e-11 44.4 0.0 1.8e-11 43.7 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Pkinase PF00069.25 AIN97207.1 - 5.2e-58 196.5 0.0 6.3e-58 196.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 AIN97207.1 - 1.2e-23 83.8 0.0 1.7e-23 83.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Choline_kinase PF01633.20 AIN97207.1 - 0.0044 16.6 0.0 0.0079 15.8 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.23 AIN97207.1 - 0.0065 16.4 0.0 0.027 14.4 0.0 1.9 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 AIN97207.1 - 0.041 13.2 0.0 0.077 12.3 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family UDPGT PF00201.18 AIN97207.1 - 0.12 11.1 0.0 0.18 10.6 0.0 1.1 1 0 0 1 1 1 0 UDP-glucoronosyl and UDP-glucosyl transferase NYD-SP28 PF14772.6 AIN97208.1 - 0.075 13.1 0.3 0.16 12.0 0.3 1.6 1 0 0 1 1 1 0 Sperm tail CoaE PF01121.20 AIN97209.1 - 4.4e-21 75.3 0.1 9.1e-06 25.5 0.1 4.1 4 0 0 4 4 4 4 Dephospho-CoA kinase AAA_18 PF13238.6 AIN97209.1 - 0.097 13.2 0.0 0.19 12.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain BLI1 PF17324.2 AIN97210.1 - 0.033 14.9 0.1 0.088 13.5 0.1 1.7 1 0 0 1 1 1 0 BLOC-1 interactor 1 DUF35_N PF12172.8 AIN97211.1 - 0.12 12.3 1.7 0.12 12.3 1.7 2.6 3 0 0 3 3 3 0 Rubredoxin-like zinc ribbon domain (DUF35_N) DUF866 PF05907.13 AIN97211.1 - 0.13 12.2 1.9 0.33 10.9 0.2 2.1 1 1 0 2 2 2 0 Eukaryotic protein of unknown function (DUF866) DUF4379 PF14311.6 AIN97212.1 - 2.2e-17 63.2 9.7 1.3e-08 35.0 1.8 2.8 2 1 0 2 2 2 2 Probable Zinc-ribbon domain Zn_Tnp_IS1595 PF12760.7 AIN97212.1 - 0.0014 18.5 8.3 0.063 13.3 2.0 3.4 3 0 0 3 3 3 1 Transposase zinc-ribbon domain DUF5313 PF17240.2 AIN97212.1 - 0.0088 16.5 0.1 0.017 15.5 0.1 1.4 1 0 0 1 1 1 1 Family of unknown function (DUF5313) Elf1 PF05129.13 AIN97212.1 - 0.013 15.6 1.5 2.8 8.1 0.1 3.1 3 0 0 3 3 3 0 Transcription elongation factor Elf1 like zinc_ribbon_10 PF10058.9 AIN97212.1 - 0.079 12.7 3.5 10 6.0 0.1 3.2 3 0 0 3 3 3 0 Predicted integral membrane zinc-ribbon metal-binding protein Zn_Tnp_IS91 PF14319.6 AIN97212.1 - 0.081 13.0 4.9 1.6 8.8 0.2 3.1 3 0 0 3 3 3 0 Transposase zinc-binding domain zf-HC5HC2H PF13771.6 AIN97212.1 - 0.3 11.4 4.5 3.2 8.0 0.5 2.8 2 1 1 3 3 3 0 PHD-like zinc-binding domain Zn_ribbon_SprT PF17283.2 AIN97212.1 - 0.4 10.6 16.4 3 7.8 4.3 3.3 3 0 0 3 3 3 0 SprT-like zinc ribbon domain VATC PF18716.1 AIN97212.1 - 0.59 10.0 7.8 8.5 6.3 3.2 3.3 2 1 0 2 2 2 0 Vms1-associating treble clef domain Zn-ribbon_8 PF09723.10 AIN97212.1 - 1.8 8.7 8.1 17 5.6 0.2 3.1 2 1 0 2 2 2 0 Zinc ribbon domain Rubredoxin_2 PF18073.1 AIN97212.1 - 1.9 8.3 15.3 2.2 8.1 0.6 3.5 3 0 0 3 3 3 0 Rubredoxin metal binding domain DZR PF12773.7 AIN97212.1 - 2 8.5 6.0 2.7 8.1 1.2 2.5 2 1 0 2 2 2 0 Double zinc ribbon zf-C3HC4_3 PF13920.6 AIN97212.1 - 3.1 7.7 5.5 3.8 7.4 0.3 2.9 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) zf-Sec23_Sec24 PF04810.15 AIN97212.1 - 3.7 7.7 10.4 2.9 8.0 0.2 3.6 4 0 0 4 4 4 0 Sec23/Sec24 zinc finger CxC5 PF18718.1 AIN97212.1 - 4.8 7.3 8.8 8.7 6.5 1.6 3.4 1 1 1 3 3 3 0 CxC5 like cysteine cluster associated with KDZ transposases DnaJ PF00226.31 AIN97213.1 - 1.7e-14 53.6 0.1 3.1e-14 52.9 0.1 1.4 1 0 0 1 1 1 1 DnaJ domain DUF446 PF04287.12 AIN97213.1 - 0.046 13.8 0.1 0.093 12.8 0.1 1.4 1 0 0 1 1 1 0 tRNA pseudouridine synthase C FAM221 PF14753.6 AIN97214.1 - 5.4e-15 55.5 20.1 4.3e-13 49.3 1.1 3.5 4 0 0 4 4 4 3 Protein FAM221A/B NOB1_Zn_bind PF08772.11 AIN97214.1 - 0.0042 17.2 0.7 0.0042 17.2 0.7 2.5 2 0 0 2 2 2 1 Nin one binding (NOB1) Zn-ribbon like ATP12 PF07542.11 AIN97215.1 - 9e-19 67.8 0.0 1.5e-18 67.1 0.0 1.4 1 0 0 1 1 1 1 ATP12 chaperone protein PPIP5K2_N PF18086.1 AIN97215.1 - 0.11 12.7 0.1 2.1 8.5 0.0 2.7 2 0 0 2 2 2 0 Diphosphoinositol pentakisphosphate kinase 2 N-terminal domain Peptidase_C13 PF01650.18 AIN97216.1 - 4.6e-35 121.4 0.0 8.8e-35 120.4 0.0 1.4 1 0 0 1 1 1 1 Peptidase C13 family TTL PF03133.15 AIN97217.1 - 6.3e-78 261.9 0.0 9e-78 261.4 0.0 1.1 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 AIN97217.1 - 9.8e-06 25.0 0.0 0.0012 18.1 0.0 2.9 3 0 0 3 3 3 1 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 AIN97217.1 - 0.0047 16.2 0.0 0.02 14.1 0.0 1.9 2 0 0 2 2 2 1 Sugar-transfer associated ATP-grasp DUF3884 PF13024.6 AIN97217.1 - 0.077 12.6 0.0 0.2 11.2 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3884) HEAT_2 PF13646.6 AIN97218.1 - 0.0038 17.6 0.3 0.37 11.2 0.0 3.4 3 0 0 3 3 3 1 HEAT repeats Nuc_sug_transp PF04142.15 AIN97220.1 - 7.8e-72 242.1 16.3 7.9e-63 212.5 7.2 2.7 2 1 0 2 2 2 2 Nucleotide-sugar transporter EamA PF00892.20 AIN97220.1 - 2.8e-06 27.6 3.3 2.8e-06 27.6 3.3 3.5 3 0 0 3 3 3 2 EamA-like transporter family UAA PF08449.11 AIN97220.1 - 6.2e-06 25.6 0.2 1.3e-05 24.5 0.2 1.5 1 0 0 1 1 1 1 UAA transporter family PUNUT PF16913.5 AIN97220.1 - 0.00033 20.0 1.1 0.00033 20.0 1.1 2.6 3 0 0 3 3 3 1 Purine nucleobase transmembrane transport TPT PF03151.16 AIN97220.1 - 0.016 14.6 0.9 0.016 14.6 0.9 2.6 3 0 0 3 3 3 0 Triose-phosphate Transporter family Citrate_synt PF00285.21 AIN97224.1 - 1.5e-94 317.0 0.0 1.9e-94 316.7 0.0 1.1 1 0 0 1 1 1 1 Citrate synthase, C-terminal domain Cytomega_gL PF01801.16 AIN97224.1 - 0.12 11.8 0.0 0.35 10.2 0.0 1.7 2 0 0 2 2 2 0 Cytomegalovirus glycoprotein L Citrate_synt PF00285.21 AIN97225.1 - 7.5e-96 321.3 0.0 9.7e-96 321.0 0.0 1.1 1 0 0 1 1 1 1 Citrate synthase, C-terminal domain Cytomega_gL PF01801.16 AIN97225.1 - 0.12 11.7 0.0 0.37 10.1 0.0 1.7 2 0 0 2 2 2 0 Cytomegalovirus glycoprotein L HEAT PF02985.22 AIN97227.1 - 2.1e-20 71.1 15.5 0.012 15.8 0.0 10.5 11 0 0 11 11 11 6 HEAT repeat HEAT_2 PF13646.6 AIN97227.1 - 2.2e-14 53.6 15.4 0.00051 20.4 0.0 7.1 4 4 2 7 7 7 5 HEAT repeats Cnd1 PF12717.7 AIN97227.1 - 3.1e-05 24.1 0.0 1.1 9.2 0.0 3.9 3 1 1 4 4 4 2 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 AIN97227.1 - 0.00019 21.8 4.3 0.024 15.1 0.0 4.7 5 0 0 5 5 5 1 HEAT-like repeat Adaptin_N PF01602.20 AIN97227.1 - 0.0012 17.4 0.1 1.8 7.1 0.1 3.4 2 1 0 3 3 3 2 Adaptin N terminal region DUF2063 PF09836.9 AIN97227.1 - 0.012 15.9 0.0 0.041 14.1 0.0 2.0 1 0 0 1 1 1 0 Putative DNA-binding domain CLASP_N PF12348.8 AIN97227.1 - 0.053 13.1 0.1 10 5.6 0.0 3.5 2 1 2 4 4 4 0 CLASP N terminal PA26 PF04636.13 AIN97228.1 - 4.3e-34 118.2 2.2 2.6e-12 46.4 0.0 3.1 3 0 0 3 3 3 3 PA26 p53-induced protein (sestrin) Pkinase PF00069.25 AIN97229.1 - 4.9e-75 252.3 0.0 5.5e-75 252.1 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 AIN97229.1 - 4.6e-39 134.3 0.0 5.5e-39 134.0 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 AIN97229.1 - 8.8e-10 38.4 0.0 1.7e-09 37.4 0.0 1.3 1 1 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 AIN97229.1 - 3.6e-07 29.5 0.0 1.1e-06 27.9 0.1 1.6 2 0 0 2 2 2 1 Haspin like kinase domain APH PF01636.23 AIN97229.1 - 1.8e-05 24.8 0.1 0.12 12.3 0.0 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 AIN97229.1 - 0.0055 16.1 0.1 0.009 15.4 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Phosducin PF02114.16 AIN97229.1 - 0.1 11.5 0.1 0.14 11.0 0.1 1.2 1 0 0 1 1 1 0 Phosducin Seadorna_VP7 PF07387.11 AIN97229.1 - 0.13 11.3 0.0 0.23 10.5 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 Phage_tail_S PF05069.13 AIN97229.1 - 0.15 11.9 0.1 0.24 11.3 0.1 1.3 1 0 0 1 1 1 0 Phage virion morphogenesis family DUF421 PF04239.12 AIN97229.1 - 0.15 11.8 1.8 0.22 11.3 0.9 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF421) Choline_kinase PF01633.20 AIN97229.1 - 0.16 11.5 0.0 0.28 10.7 0.0 1.5 1 1 0 1 1 1 0 Choline/ethanolamine kinase DUF2587 PF10759.9 AIN97230.1 - 0.058 12.9 0.0 0.13 11.8 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2587) Ribosomal_L1 PF00687.21 AIN97231.1 - 4.2e-41 140.9 2.3 5.2e-41 140.6 2.3 1.0 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family Peptidase_M41 PF01434.18 AIN97232.1 - 8.1e-47 159.5 1.5 1.2e-46 159.0 1.5 1.2 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.29 AIN97232.1 - 3.1e-39 134.4 0.0 5.6e-39 133.6 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 AIN97232.1 - 7.7e-06 26.4 1.0 3.2e-05 24.4 0.0 2.3 1 1 1 2 2 2 1 AAA ATPase domain AAA_5 PF07728.14 AIN97232.1 - 0.00034 20.6 0.1 0.0021 18.1 0.0 2.3 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 AIN97232.1 - 0.00053 20.3 0.6 0.016 15.5 0.1 3.0 1 1 2 3 3 3 1 AAA domain AAA_2 PF07724.14 AIN97232.1 - 0.00073 19.7 0.1 0.0034 17.5 0.1 2.2 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) RuvB_N PF05496.12 AIN97232.1 - 0.0062 16.3 0.2 0.11 12.3 0.0 3.0 3 0 0 3 3 3 1 Holliday junction DNA helicase RuvB P-loop domain TIP49 PF06068.13 AIN97232.1 - 0.0085 15.3 0.0 0.021 14.0 0.0 1.6 1 0 0 1 1 1 1 TIP49 P-loop domain Peptidase_M50B PF13398.6 AIN97232.1 - 0.0097 15.6 0.0 0.019 14.6 0.0 1.4 1 0 0 1 1 1 1 Peptidase M50B-like Sigma54_activat PF00158.26 AIN97232.1 - 0.011 15.4 0.0 0.033 13.9 0.0 1.8 1 1 0 1 1 1 0 Sigma-54 interaction domain AAA_lid_3 PF17862.1 AIN97232.1 - 0.023 14.5 0.0 0.061 13.1 0.0 1.7 1 0 0 1 1 1 0 AAA+ lid domain Zeta_toxin PF06414.12 AIN97232.1 - 0.036 13.3 0.1 1.1 8.5 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin AAA_24 PF13479.6 AIN97232.1 - 0.056 13.2 0.0 0.11 12.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 AIN97232.1 - 0.075 12.8 0.1 0.15 11.8 0.1 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein DUF2075 PF09848.9 AIN97232.1 - 0.1 11.8 0.1 0.16 11.2 0.1 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) ATPase PF06745.13 AIN97232.1 - 0.11 11.8 0.1 0.29 10.5 0.1 1.6 1 0 0 1 1 1 0 KaiC NACHT PF05729.12 AIN97232.1 - 0.14 12.0 0.1 0.65 9.9 0.1 2.1 2 0 0 2 2 2 0 NACHT domain Dpy-30 PF05186.13 AIN97233.1 - 3.4e-11 42.6 0.3 5.6e-11 42.0 0.3 1.4 1 0 0 1 1 1 1 Dpy-30 motif Ribosomal_S27e PF01667.17 AIN97234.1 - 4.1e-22 77.7 3.0 5e-22 77.4 3.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S27 FYVE_2 PF02318.16 AIN97234.1 - 0.019 15.2 0.7 0.022 15.0 0.7 1.1 1 0 0 1 1 1 0 FYVE-type zinc finger Zn_Tnp_IS1595 PF12760.7 AIN97234.1 - 0.023 14.7 1.8 0.037 14.0 1.8 1.5 1 0 0 1 1 1 0 Transposase zinc-ribbon domain HypA PF01155.19 AIN97234.1 - 0.12 12.4 1.8 0.14 12.2 1.8 1.2 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zinc_ribbon_4 PF13717.6 AIN97234.1 - 0.17 11.8 4.7 4.1 7.4 4.7 2.4 1 1 0 1 1 1 0 zinc-ribbon domain FYVE PF01363.21 AIN97235.1 - 1.3e-19 70.1 7.5 1.3e-19 70.1 7.5 4.6 3 2 1 4 4 4 1 FYVE zinc finger zf-RanBP PF00641.18 AIN97235.1 - 1.1e-13 50.2 62.7 1.8e-06 27.2 2.0 6.7 7 0 0 7 7 7 5 Zn-finger in Ran binding protein and others Vps36-NZF-N PF16988.5 AIN97235.1 - 0.00019 20.7 35.7 0.15 11.5 0.4 6.7 6 2 0 6 6 6 5 Vacuolar protein sorting 36 NZF-N zinc-finger domain DZR PF12773.7 AIN97235.1 - 0.0074 16.3 49.4 0.2 11.7 8.6 5.7 3 2 2 5 5 5 4 Double zinc ribbon RRM_1 PF00076.22 AIN97236.1 - 2.9e-18 65.5 0.0 6.4e-18 64.4 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 AIN97236.1 - 0.00033 20.3 0.3 0.00092 18.8 0.0 1.9 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 AIN97236.1 - 0.0065 16.5 0.0 0.017 15.1 0.0 1.8 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif RRM_7 PF16367.5 AIN97236.1 - 0.026 14.6 0.2 0.088 12.9 0.0 2.1 2 1 0 2 2 2 0 RNA recognition motif RRM_3 PF08777.11 AIN97236.1 - 0.19 11.8 0.0 0.65 10.1 0.0 1.8 2 0 0 2 2 2 0 RNA binding motif Suf PF05843.14 AIN97236.1 - 0.37 10.7 14.4 0.1 12.6 8.2 2.1 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) WSD PF15613.6 AIN97236.1 - 0.38 11.3 1.7 28 5.3 0.1 2.6 3 0 0 3 3 3 0 Williams-Beuren syndrome DDT (WSD), D-TOX E motif Presenilin PF01080.17 AIN97236.1 - 5.2 5.7 6.9 1.6 7.4 2.9 1.9 2 0 0 2 2 2 0 Presenilin ECH_1 PF00378.20 AIN97237.1 - 6.3e-31 107.6 0.3 9.3e-30 103.8 0.1 2.0 1 1 1 2 2 2 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 AIN97237.1 - 7.4e-12 45.4 0.2 2.1e-11 43.9 0.2 1.7 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ASH PF15780.5 AIN97238.1 - 1.1e-27 96.1 7.0 0.0059 16.8 0.0 9.0 8 1 1 9 9 9 6 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin DUF1573 PF07610.11 AIN97238.1 - 2.2e-12 46.9 0.0 0.00025 21.0 0.0 8.1 9 1 0 9 9 9 1 Protein of unknown function (DUF1573) PapD-like PF14874.6 AIN97238.1 - 2.7e-12 46.7 2.6 0.0044 17.2 0.0 5.4 5 0 0 5 5 5 2 Flagellar-associated PapD-like TMEM131_like PF12371.8 AIN97238.1 - 2.2e-05 24.6 6.3 0.64 10.3 0.2 5.9 6 0 0 6 6 6 1 Transmembrane protein 131-like Motile_Sperm PF00635.26 AIN97238.1 - 0.00058 19.7 1.1 0.037 13.9 0.0 4.3 5 0 0 5 5 5 1 MSP (Major sperm protein) domain PapD_N PF00345.20 AIN97238.1 - 0.053 13.4 0.0 5.6 6.9 0.0 3.2 2 0 0 2 2 2 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain V-ATPase_C PF03223.15 AIN97239.1 - 3e-84 283.5 1.3 3.7e-84 283.3 1.3 1.0 1 0 0 1 1 1 1 V-ATPase subunit C Phi29_Phage_SSB PF17427.2 AIN97240.1 - 0.031 14.5 0.4 0.091 13.0 0.3 1.9 1 1 0 1 1 1 0 Phage Single-stranded DNA-binding protein MRP-S26 PF14943.6 AIN97240.1 - 0.045 13.7 8.9 0.078 12.9 8.9 1.3 1 0 0 1 1 1 0 Mitochondrial ribosome subunit S26 TBCC PF07986.12 AIN97242.1 - 3.9e-34 117.0 0.1 6e-34 116.3 0.1 1.3 1 0 0 1 1 1 1 Tubulin binding cofactor C FOP_dimer PF09398.10 AIN97242.1 - 6.6e-05 23.1 0.0 0.00012 22.2 0.0 1.4 1 0 0 1 1 1 1 FOP N terminal dimerisation domain CAP_C PF08603.11 AIN97242.1 - 0.0038 16.8 1.0 0.0058 16.2 0.3 1.6 2 0 0 2 2 2 1 Adenylate cyclase associated (CAP) C terminal LisH_2 PF16045.5 AIN97242.1 - 0.1 11.7 0.2 0.19 10.8 0.2 1.5 1 0 0 1 1 1 0 LisH MRI PF15325.6 AIN97242.1 - 0.9 10.7 9.6 17 6.6 7.0 2.7 2 0 0 2 2 2 0 Modulator of retrovirus infection FlaC_arch PF05377.11 AIN97243.1 - 0.19 12.2 3.2 29 5.1 0.3 3.5 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) Lectin_N PF03954.14 AIN97243.1 - 1.4 8.7 11.2 0.57 9.9 0.8 3.6 2 1 1 3 3 3 0 Hepatic lectin, N-terminal domain LemA PF04011.12 AIN97243.1 - 1.5 8.6 12.0 0.041 13.7 3.9 2.4 2 1 0 2 2 2 0 LemA family Fez1 PF06818.15 AIN97243.1 - 2.4 8.6 31.3 15 6.0 3.6 3.0 2 1 0 2 2 2 0 Fez1 Phage_GP20 PF06810.11 AIN97243.1 - 3.7 7.3 10.7 3.3 7.5 0.7 3.1 3 0 0 3 3 3 0 Phage minor structural protein GP20 DUF4482 PF14818.6 AIN97243.1 - 5.6 7.8 13.6 0.81 10.6 7.1 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF4482) Aconitase PF00330.20 AIN97244.1 - 2.2e-179 597.3 0.0 2.9e-179 596.9 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 AIN97244.1 - 7.7e-42 142.7 0.0 1.4e-41 141.9 0.0 1.4 1 0 0 1 1 1 1 Aconitase C-terminal domain PPR_3 PF13812.6 AIN97245.1 - 0.00067 19.7 0.0 0.4 10.8 0.0 3.1 3 0 0 3 3 3 2 Pentatricopeptide repeat domain PPR_1 PF12854.7 AIN97245.1 - 0.17 11.6 0.0 0.52 10.1 0.0 1.8 1 0 0 1 1 1 0 PPR repeat BTB_2 PF02214.22 AIN97246.1 - 5e-13 49.2 0.0 7.9e-13 48.6 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain UDG PF03167.19 AIN97247.1 - 3.5e-18 66.1 0.0 5.2e-18 65.5 0.0 1.2 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily WD40 PF00400.32 AIN97248.1 - 2.6e-40 135.6 19.5 8.5e-07 29.6 0.2 7.5 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 AIN97248.1 - 1.1e-10 41.6 3.0 0.02 15.2 0.1 5.3 2 1 3 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 AIN97248.1 - 0.0074 15.0 0.6 1 7.9 0.0 2.5 1 1 1 2 2 2 2 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 AIN97248.1 - 0.11 11.5 0.1 7.6 5.4 0.0 3.0 2 1 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein ABC_tran_CTD PF16326.5 AIN97248.1 - 0.11 12.7 4.7 17 5.7 0.0 2.5 2 0 0 2 2 2 0 ABC transporter C-terminal domain CENP-F_leu_zip PF10473.9 AIN97248.1 - 0.38 10.8 17.3 0.65 10.0 17.3 1.3 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 PALB2_WD40 PF16756.5 AIN97248.1 - 0.48 9.3 7.2 5.2 5.9 0.3 3.0 2 1 1 3 3 3 0 Partner and localizer of BRCA2 WD40 domain ZapB PF06005.12 AIN97248.1 - 0.77 10.2 13.7 1.2 9.6 0.4 2.4 2 1 0 2 2 2 0 Cell division protein ZapB Ubiquitin_2 PF14560.6 AIN97249.1 - 2.1e-22 79.4 0.0 3.9e-22 78.5 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-like domain CAP_GLY PF01302.25 AIN97249.1 - 6.2e-20 71.0 0.7 1.1e-19 70.2 0.7 1.4 1 0 0 1 1 1 1 CAP-Gly domain ubiquitin PF00240.23 AIN97249.1 - 0.006 16.3 0.0 0.051 13.3 0.0 2.2 1 1 0 1 1 1 1 Ubiquitin family Peptidase_S10 PF00450.22 AIN97250.1 - 2.5e-106 356.6 0.4 3.1e-106 356.3 0.4 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Collar PF07484.12 AIN97250.1 - 0.03 14.3 0.3 1.3 9.1 0.0 2.9 3 0 0 3 3 3 0 Phage Tail Collar Domain Peptidase_S9 PF00326.21 AIN97250.1 - 0.12 11.9 0.0 1.8 8.0 0.1 2.2 2 0 0 2 2 2 0 Prolyl oligopeptidase family PAP2 PF01569.21 AIN97251.1 - 6.7e-26 90.7 3.2 6.7e-26 90.7 3.2 2.0 2 0 0 2 2 2 1 PAP2 superfamily PAP2 PF01569.21 AIN97252.1 - 1.6e-22 79.8 1.2 1.6e-22 79.8 1.2 2.1 2 1 0 2 2 2 1 PAP2 superfamily DUF4233 PF14017.6 AIN97252.1 - 1.7 9.1 12.7 0.56 10.6 9.3 2.0 3 1 0 3 3 3 0 Protein of unknown function (DUF4233) AAA_16 PF13191.6 AIN97253.1 - 0.0071 16.7 6.6 0.034 14.5 0.1 3.8 3 1 0 3 3 3 1 AAA ATPase domain DUF4404 PF14357.6 AIN97253.1 - 0.17 12.6 1.1 9.5 6.9 0.4 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4404) Tctex-1 PF03645.13 AIN97254.1 - 1e-16 61.0 0.1 1.7e-16 60.3 0.1 1.4 1 0 0 1 1 1 1 Tctex-1 family RNA_pol_Rpo13 PF12136.8 AIN97254.1 - 3.6 7.6 9.0 40 4.2 0.0 2.5 2 0 0 2 2 2 0 RNA polymerase Rpo13 subunit HTH domain GTP_EFTU PF00009.27 AIN97255.1 - 4.7e-53 179.6 0.3 8.1e-53 178.8 0.3 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 AIN97255.1 - 9.6e-19 67.7 0.0 1e-17 64.4 0.0 2.4 1 1 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 AIN97255.1 - 2.4e-07 31.0 0.5 5.9e-07 29.8 0.5 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 AIN97255.1 - 0.0041 17.2 0.0 0.01 15.9 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase PduV-EutP PF10662.9 AIN97255.1 - 0.065 13.0 0.8 2.5 7.8 0.8 2.4 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation zf-C2H2_jaz PF12171.8 AIN97257.1 - 2.7e-07 30.7 2.4 4.3e-07 30.0 2.4 1.3 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 AIN97257.1 - 4.8e-07 30.0 1.0 7.9e-07 29.3 1.0 1.4 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.7 AIN97257.1 - 0.0002 21.6 0.1 0.00026 21.2 0.1 1.1 1 0 0 1 1 1 1 C2H2 type zinc-finger (2 copies) zf-DBF PF07535.12 AIN97257.1 - 0.028 14.5 1.0 0.044 13.9 1.0 1.3 1 0 0 1 1 1 0 DBF zinc finger Yippee-Mis18 PF03226.14 AIN97257.1 - 0.056 13.7 0.0 0.071 13.3 0.0 1.2 1 0 0 1 1 1 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly DUF4187 PF13821.6 AIN97257.1 - 0.057 13.2 0.1 0.12 12.2 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4187) zf-C2H2 PF00096.26 AIN97257.1 - 0.14 12.6 0.3 0.28 11.7 0.3 1.5 1 0 0 1 1 1 0 Zinc finger, C2H2 type PDZ_6 PF17820.1 AIN97258.1 - 4e-06 26.6 0.1 9e-06 25.4 0.1 1.6 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 AIN97258.1 - 0.00017 21.8 0.0 0.00052 20.3 0.0 1.8 1 0 0 1 1 1 1 PDZ domain RNA_pol_Rpb5_C PF01191.19 AIN97259.1 - 1.6e-29 101.6 0.2 3.1e-29 100.6 0.2 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb5, C-terminal domain RNA_pol_Rpb5_N PF03871.14 AIN97259.1 - 9.8e-23 80.6 0.0 2.2e-22 79.4 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb5, N-terminal domain DUF1860 PF08949.10 AIN97259.1 - 0.21 11.3 0.0 0.31 10.8 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1860) RNA_pol_Rpb5_C PF01191.19 AIN97260.1 - 6.6e-22 77.2 0.0 1.4e-21 76.1 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb5, C-terminal domain RNA_pol_Rpb5_N PF03871.14 AIN97260.1 - 1e-08 35.6 0.0 0.00027 21.4 0.0 2.6 2 0 0 2 2 2 2 RNA polymerase Rpb5, N-terminal domain GMAP PF06540.11 AIN97260.1 - 0.17 12.0 0.2 0.32 11.1 0.2 1.4 1 0 0 1 1 1 0 Galanin message associated peptide (GMAP) Ribosomal_S8 PF00410.19 AIN97261.1 - 1.3e-07 31.6 0.0 1.9e-07 31.0 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S8 CDP-OH_P_transf PF01066.21 AIN97262.1 - 4.9e-17 62.5 0.0 4.9e-17 62.5 0.0 3.6 3 2 0 3 3 3 1 CDP-alcohol phosphatidyltransferase HEAT_EZ PF13513.6 AIN97263.1 - 0.69 10.5 22.4 1.6 9.3 0.0 8.2 10 0 0 10 10 10 0 HEAT-like repeat WD40 PF00400.32 AIN97264.1 - 7.1e-25 86.8 16.0 1.3e-06 29.0 0.1 10.7 12 0 0 12 12 12 7 WD domain, G-beta repeat Utp12 PF04003.12 AIN97264.1 - 4.6e-12 46.2 0.3 1.2e-11 44.8 0.1 1.9 2 0 0 2 2 2 1 Dip2/Utp12 Family ANAPC4_WD40 PF12894.7 AIN97264.1 - 6.1e-11 42.5 0.0 0.044 14.1 0.0 7.2 6 1 1 7 7 7 2 Anaphase-promoting complex subunit 4 WD40 domain DUF1513 PF07433.11 AIN97264.1 - 0.00032 19.9 0.4 0.063 12.4 0.0 3.1 3 0 0 3 3 3 2 Protein of unknown function (DUF1513) 14-3-3 PF00244.20 AIN97265.1 - 0.23 10.9 0.0 3.3 7.1 0.0 2.3 2 0 0 2 2 2 0 14-3-3 protein DUF4632 PF15451.6 AIN97266.1 - 7.9 6.6 6.4 3 8.0 0.0 3.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4632) ACBP PF00887.19 AIN97267.1 - 0.0098 16.1 0.0 0.029 14.6 0.0 1.8 1 0 0 1 1 1 1 Acyl CoA binding protein Pro_isomerase PF00160.21 AIN97269.1 - 3.3e-32 112.0 0.0 8.1e-32 110.7 0.0 1.7 2 0 0 2 2 2 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Ras PF00071.22 AIN97270.1 - 8.6e-54 181.5 2.1 1.1e-52 177.9 2.1 2.0 1 1 0 1 1 1 1 Ras family Roc PF08477.13 AIN97270.1 - 1.7e-35 121.9 0.1 3.2e-35 120.9 0.1 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 AIN97270.1 - 6e-12 45.4 0.0 7.1e-12 45.1 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 AIN97270.1 - 2.7e-06 26.9 0.0 3.2e-06 26.7 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 AIN97270.1 - 5e-06 26.6 0.0 1.1e-05 25.5 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 AIN97270.1 - 6.3e-05 22.6 0.7 0.002 17.7 0.7 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 AIN97270.1 - 0.0031 17.4 0.1 0.067 13.1 0.1 2.4 1 1 0 2 2 2 1 RsgA GTPase AAA_24 PF13479.6 AIN97270.1 - 0.0066 16.2 0.2 0.054 13.2 0.0 2.0 2 0 0 2 2 2 1 AAA domain cobW PF02492.19 AIN97270.1 - 0.011 15.3 0.1 2.5 7.6 0.0 2.3 1 1 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_16 PF13191.6 AIN97270.1 - 0.021 15.2 0.2 0.027 14.9 0.2 1.5 1 1 0 1 1 1 0 AAA ATPase domain PduV-EutP PF10662.9 AIN97270.1 - 0.04 13.7 0.0 0.12 12.1 0.0 1.8 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation NB-ARC PF00931.22 AIN97270.1 - 0.055 12.6 0.2 0.053 12.7 0.2 1.4 1 1 0 1 1 1 0 NB-ARC domain AAA_22 PF13401.6 AIN97270.1 - 0.057 13.7 0.0 0.099 12.9 0.0 1.5 1 1 0 1 1 1 0 AAA domain NACHT PF05729.12 AIN97270.1 - 0.059 13.3 0.0 0.095 12.6 0.0 1.3 1 0 0 1 1 1 0 NACHT domain DAP3 PF10236.9 AIN97270.1 - 0.07 12.3 0.0 0.12 11.5 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 SRPRB PF09439.10 AIN97270.1 - 0.071 12.5 0.0 0.11 11.9 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_7 PF12775.7 AIN97270.1 - 0.08 12.4 0.0 0.15 11.6 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_5 PF07728.14 AIN97270.1 - 0.083 12.9 0.0 0.14 12.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) RNA_helicase PF00910.22 AIN97270.1 - 0.12 12.8 0.0 0.61 10.5 0.0 2.1 1 1 0 1 1 1 0 RNA helicase NTPase_1 PF03266.15 AIN97270.1 - 0.13 12.1 0.0 0.19 11.6 0.0 1.3 1 0 0 1 1 1 0 NTPase TniB PF05621.11 AIN97270.1 - 0.14 11.5 0.0 0.2 11.0 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein Glyco_trans_1_4 PF13692.6 AIN97271.1 - 5e-05 23.7 0.0 0.00022 21.7 0.0 2.0 1 1 0 1 1 1 1 Glycosyl transferases group 1 PPR_3 PF13812.6 AIN97272.1 - 0.00012 22.1 0.0 0.0089 16.1 0.0 2.7 2 1 0 2 2 2 1 Pentatricopeptide repeat domain PPR_long PF17177.4 AIN97272.1 - 0.00015 21.2 0.7 0.024 14.0 0.1 2.4 1 1 1 2 2 2 2 Pentacotripeptide-repeat region of PRORP PPR_2 PF13041.6 AIN97272.1 - 0.00029 20.9 0.0 0.46 10.7 0.0 3.4 2 1 1 3 3 3 2 PPR repeat family WD40 PF00400.32 AIN97273.1 - 6.1e-05 23.7 11.8 0.035 15.0 0.6 5.6 5 1 1 6 6 6 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 AIN97273.1 - 6.9e-05 23.1 0.7 11 6.4 0.1 4.6 4 1 0 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Myosin_TH1 PF06017.13 AIN97274.1 - 0.0042 16.8 0.0 0.0073 16.0 0.0 1.3 1 0 0 1 1 1 1 Unconventional myosin tail, actin- and lipid-binding Lectin_N PF03954.14 AIN97274.1 - 0.074 12.8 3.2 0.42 10.4 0.6 2.4 2 0 0 2 2 2 0 Hepatic lectin, N-terminal domain Halo_GVPC PF05465.13 AIN97274.1 - 0.14 12.5 2.0 0.65 10.3 0.8 2.5 2 0 0 2 2 2 0 Halobacterial gas vesicle protein C (GVPC) repeat Nrap_D5 PF17406.2 AIN97275.1 - 2.6e-30 105.3 0.0 5.5e-30 104.3 0.0 1.6 1 0 0 1 1 1 1 Nrap protein PAP/OAS1-like domain 5 Nrap_D3 PF17404.2 AIN97275.1 - 9.1e-17 61.6 0.0 1.8e-16 60.7 0.0 1.5 1 0 0 1 1 1 1 Nrap protein domain 3 Nrap_D4 PF17405.2 AIN97275.1 - 1.9e-16 60.1 0.0 3.7e-16 59.1 0.0 1.4 1 0 0 1 1 1 1 Nrap protein nucleotidyltransferase domain 4 Nrap_D2 PF17403.2 AIN97275.1 - 1.7e-06 27.9 0.0 0.00017 21.4 0.0 2.8 3 0 0 3 3 3 1 Nrap protein PAP/OAS-like domain Mannosyl_trans2 PF04188.13 AIN97277.1 - 1.5e-30 107.0 29.5 2.6e-19 69.9 14.4 4.1 4 0 0 4 4 4 4 Mannosyltransferase (PIG-V) IQ PF00612.27 AIN97278.1 - 0.014 15.1 4.7 2.3 8.2 0.0 3.1 2 0 0 2 2 2 0 IQ calmodulin-binding motif EPL1 PF10513.9 AIN97279.1 - 0.14 12.6 6.4 0.19 12.1 6.4 1.2 1 0 0 1 1 1 0 Enhancer of polycomb-like PIN_2 PF10130.9 AIN97279.1 - 0.14 12.4 4.7 0.053 13.7 1.9 1.7 2 0 0 2 2 2 0 PIN domain Cupin_8 PF13621.6 AIN97279.1 - 0.14 11.9 3.5 0.16 11.7 3.5 1.3 1 0 0 1 1 1 0 Cupin-like domain DUF4407 PF14362.6 AIN97279.1 - 1.8 7.9 16.0 3 7.1 15.8 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) FUSC PF04632.12 AIN97279.1 - 6.1 5.3 5.3 6.7 5.1 5.3 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family UDPGP PF01704.18 AIN97280.1 - 5.4e-116 387.6 0.0 1.3e-115 386.4 0.0 1.5 1 1 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase ERCC3_RAD25_C PF16203.5 AIN97280.1 - 0.13 11.4 0.1 0.33 10.1 0.0 1.6 2 0 0 2 2 2 0 ERCC3/RAD25/XPB C-terminal helicase Mito_carr PF00153.27 AIN97281.1 - 2.6e-19 68.9 2.2 1.8e-09 37.4 0.0 3.7 3 1 0 3 3 3 3 Mitochondrial carrier protein Robl_LC7 PF03259.17 AIN97282.1 - 1.6e-21 75.9 0.0 1.8e-21 75.7 0.0 1.0 1 0 0 1 1 1 1 Roadblock/LC7 domain NikR_C PF08753.11 AIN97282.1 - 0.01 16.0 0.1 0.15 12.2 0.0 2.3 2 0 0 2 2 2 0 NikR C terminal nickel binding domain LAMTOR5 PF16672.5 AIN97282.1 - 0.012 15.5 0.0 0.018 14.9 0.0 1.3 1 0 0 1 1 1 0 Ragulator complex protein LAMTOR5 PhoD PF09423.10 AIN97284.1 - 1.2e-07 31.1 0.1 0.00014 21.0 0.1 2.9 2 1 0 2 2 2 2 PhoD-like phosphatase Hydantoinase_B PF02538.14 AIN97285.1 - 3.3e-197 656.0 0.6 5.1e-197 655.4 0.6 1.2 1 0 0 1 1 1 1 Hydantoinase B/oxoprolinase Hydantoinase_A PF01968.18 AIN97285.1 - 7.9e-93 310.9 1.0 7.9e-93 310.9 1.0 2.0 3 0 0 3 3 3 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.13 AIN97285.1 - 8.5e-53 178.7 0.6 3.3e-51 173.5 0.1 2.5 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase N-terminal region Nkap_C PF06047.11 AIN97285.1 - 0.0038 17.3 0.0 0.0091 16.1 0.0 1.5 1 0 0 1 1 1 1 NF-kappa-B-activating protein C-terminal domain CUT PF02376.15 AIN97286.1 - 0.069 13.3 0.0 0.19 11.9 0.0 1.7 1 0 0 1 1 1 0 CUT domain Nup54_57_C PF18570.1 AIN97286.1 - 0.21 11.2 0.6 0.45 10.2 0.6 1.5 1 0 0 1 1 1 0 NUP57/Nup54 C-terminal domain Peptidase_C2 PF00648.21 AIN97287.1 - 1.8e-15 56.8 0.0 1.1e-14 54.1 0.0 1.9 1 1 0 1 1 1 1 Calpain family cysteine protease Vps16_C PF04840.12 AIN97288.1 - 1.6e-24 86.6 0.2 2.8e-12 46.3 0.0 2.4 2 0 0 2 2 2 2 Vps16, C-terminal region Vps16_N PF04841.13 AIN97288.1 - 1.7e-18 66.6 0.0 3.2e-18 65.7 0.0 1.4 1 0 0 1 1 1 1 Vps16, N-terminal region AAA_28 PF13521.6 AIN97288.1 - 0.075 13.3 0.2 0.38 11.0 0.0 2.3 2 1 0 2 2 2 0 AAA domain RNA_bind PF08675.11 AIN97288.1 - 0.15 12.1 0.0 28 4.8 0.1 2.7 2 0 0 2 2 2 0 RNA binding domain Pkinase PF00069.25 AIN97289.1 - 2.4e-73 246.8 0.0 2.8e-73 246.5 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 AIN97289.1 - 7.9e-37 126.9 0.0 9.6e-37 126.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 AIN97289.1 - 3.8e-07 29.7 0.0 4.5e-07 29.5 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 AIN97289.1 - 0.0017 17.2 0.0 0.0093 14.8 0.0 1.8 2 0 0 2 2 2 1 Fungal protein kinase APH PF01636.23 AIN97289.1 - 0.038 13.9 0.0 0.11 12.4 0.0 1.5 1 1 0 1 1 1 0 Phosphotransferase enzyme family Haspin_kinase PF12330.8 AIN97289.1 - 0.095 11.6 0.1 0.14 11.1 0.1 1.2 1 0 0 1 1 1 0 Haspin like kinase domain PDEase_I PF00233.19 AIN97290.1 - 1.8e-79 266.8 0.2 1.8e-79 266.8 0.2 2.6 3 0 0 3 3 3 1 3'5'-cyclic nucleotide phosphodiesterase Ank_2 PF12796.7 AIN97291.1 - 2.2e-21 76.3 0.3 2.7e-11 43.9 0.0 2.7 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 AIN97291.1 - 2.3e-18 64.4 0.0 0.00024 21.3 0.0 4.3 4 0 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.6 AIN97291.1 - 2e-17 63.0 0.8 8.3e-05 22.8 0.0 4.3 3 1 1 4 4 4 4 Ankyrin repeats (many copies) Ank_4 PF13637.6 AIN97291.1 - 6.4e-17 61.7 0.5 7.5e-12 45.5 0.1 3.1 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.30 AIN97291.1 - 2.9e-14 52.8 0.0 0.00022 21.5 0.0 3.4 3 0 0 3 3 3 3 Ankyrin repeat Methyltr_RsmB-F PF01189.17 AIN97292.1 - 2.2e-33 115.6 0.0 3.9e-33 114.8 0.0 1.4 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F FtsJ PF01728.19 AIN97292.1 - 0.0001 22.4 0.0 0.00022 21.4 0.0 1.5 1 0 0 1 1 1 1 FtsJ-like methyltransferase zf-AN1 PF01428.16 AIN97293.1 - 1.4e-15 57.2 34.2 4.7e-09 36.3 10.2 3.1 2 1 1 3 3 3 2 AN1-like Zinc finger Transp_Tc5_C PF04236.15 AIN97293.1 - 0.00025 21.4 18.0 0.016 15.6 4.1 2.7 2 0 0 2 2 2 2 Tc5 transposase C-terminal domain IBR PF01485.21 AIN97293.1 - 0.92 9.8 24.4 0.036 14.3 3.0 2.9 2 1 1 3 3 3 0 IBR domain, a half RING-finger domain zf-HIT PF04438.16 AIN97293.1 - 2.7 8.0 17.7 0.17 11.8 2.4 3.0 3 0 0 3 3 3 0 HIT zinc finger zf-C2H2_4 PF13894.6 AIN97293.1 - 9.3 7.4 21.6 1.1 10.3 3.5 3.9 3 0 0 3 3 3 0 C2H2-type zinc finger Ras PF00071.22 AIN97294.1 - 6.2e-51 172.2 0.0 1.9e-50 170.6 0.0 1.7 1 1 0 1 1 1 1 Ras family Roc PF08477.13 AIN97294.1 - 1.5e-31 109.1 0.0 4.4e-30 104.4 0.0 2.2 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 AIN97294.1 - 8.3e-11 41.6 0.0 2.1e-09 37.1 0.0 2.1 1 1 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 AIN97294.1 - 0.00013 21.4 0.0 0.00017 21.0 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_24 PF13479.6 AIN97294.1 - 0.0086 15.8 0.0 0.051 13.3 0.0 1.9 2 0 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 AIN97294.1 - 0.012 15.5 0.1 0.16 11.9 0.0 2.1 2 0 0 2 2 2 0 RsgA GTPase ABC_tran PF00005.27 AIN97294.1 - 0.018 15.6 0.0 0.028 14.9 0.0 1.5 1 1 0 1 1 1 0 ABC transporter MMR_HSR1 PF01926.23 AIN97294.1 - 0.037 14.1 0.0 0.18 11.9 0.0 2.0 1 1 0 1 1 1 0 50S ribosome-binding GTPase TniB PF05621.11 AIN97294.1 - 0.16 11.4 0.0 0.33 10.3 0.0 1.5 1 0 0 1 1 1 0 Bacterial TniB protein APG6_N PF17675.1 AIN97295.1 - 0.0079 16.7 2.1 0.0079 16.7 2.1 9.5 3 1 6 9 9 9 1 Apg6 coiled-coil region SOGA PF11365.8 AIN97295.1 - 0.01 16.9 5.0 0.01 16.9 5.0 9.5 7 2 0 8 8 8 0 Protein SOGA zf-C3HC4_3 PF13920.6 AIN97296.1 - 2.4e-16 59.3 11.0 4.2e-16 58.5 11.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 AIN97296.1 - 6.1e-07 29.7 12.7 1.2e-06 28.7 12.7 1.6 1 0 0 1 1 1 1 Ring finger domain Prok-RING_4 PF14447.6 AIN97296.1 - 8.1e-07 28.8 12.6 1.5e-06 27.9 12.6 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 AIN97296.1 - 0.0011 18.7 16.0 0.0021 17.8 16.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zinc_ribbon_2 PF13240.6 AIN97296.1 - 0.0026 17.4 0.8 0.0066 16.1 0.8 1.7 1 0 0 1 1 1 1 zinc-ribbon domain zf-RING_5 PF14634.6 AIN97296.1 - 0.01 15.8 11.9 0.019 14.9 11.9 1.5 1 0 0 1 1 1 0 zinc-RING finger domain Mannitol_dh PF01232.23 AIN97296.1 - 0.06 13.5 0.0 0.11 12.6 0.0 1.4 1 0 0 1 1 1 0 Mannitol dehydrogenase Rossmann domain zf-P11 PF03854.14 AIN97296.1 - 0.32 10.7 10.3 0.69 9.6 10.3 1.6 1 1 0 1 1 1 0 P-11 zinc finger zf-C4H2 PF10146.9 AIN97296.1 - 0.63 10.3 8.5 2.2 8.5 8.5 2.0 1 1 0 1 1 1 0 Zinc finger-containing protein DZR PF12773.7 AIN97296.1 - 1.7 8.7 8.6 8.3 6.5 8.9 1.8 1 1 0 1 1 1 0 Double zinc ribbon zf-RING_10 PF16685.5 AIN97296.1 - 2 8.6 9.9 5.1 7.3 9.9 1.7 1 0 0 1 1 1 0 zinc RING finger of MSL2 TPR_7 PF13176.6 AIN97297.1 - 0.096 12.8 0.4 0.23 11.6 0.4 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat CAP59_mtransfer PF11735.8 AIN97297.1 - 0.11 12.2 0.0 0.13 12.0 0.0 1.1 1 0 0 1 1 1 0 Cryptococcal mannosyltransferase 1 Cmc1 PF08583.10 AIN97298.1 - 0.006 16.6 2.3 0.013 15.4 2.3 1.6 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like NPV_P10 PF05531.12 AIN97299.1 - 5.4 7.5 11.2 0.32 11.5 1.6 3.2 4 0 0 4 4 4 0 Nucleopolyhedrovirus P10 protein DUF2196 PF09962.9 AIN97300.1 - 0.2 11.7 0.0 0.41 10.7 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2196) Complex1_LYR PF05347.15 AIN97301.1 - 1.9e-11 43.8 1.9 4.2e-11 42.7 1.9 1.6 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 AIN97301.1 - 0.074 13.8 0.8 0.074 13.8 0.8 1.9 2 0 0 2 2 2 0 Complex1_LYR-like tRNA_edit PF04073.15 AIN97302.1 - 1.3e-15 57.5 0.1 2.3e-15 56.7 0.1 1.4 1 0 0 1 1 1 1 Aminoacyl-tRNA editing domain ProRS-C_1 PF09180.11 AIN97303.1 - 4.2e-23 81.3 1.7 1.1e-22 80.0 1.7 1.8 1 0 0 1 1 1 1 Prolyl-tRNA synthetase, C-terminal tRNA_edit PF04073.15 AIN97303.1 - 4.1e-22 78.6 0.1 7.6e-22 77.7 0.1 1.5 1 0 0 1 1 1 1 Aminoacyl-tRNA editing domain tRNA-synt_2b PF00587.25 AIN97303.1 - 2e-17 63.7 0.0 3.4e-17 63.0 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 AIN97303.1 - 4.6e-15 55.5 0.0 1.5e-14 53.9 0.0 1.9 2 0 0 2 2 2 1 Anticodon binding domain SET PF00856.28 AIN97304.1 - 1.9e-10 41.4 0.0 3.5e-10 40.5 0.0 1.4 1 0 0 1 1 1 1 SET domain PIH1 PF08190.12 AIN97305.1 - 1.7e-17 63.4 0.0 7.4e-08 32.0 0.0 3.5 3 0 0 3 3 3 3 PIH1 N-terminal domain PIH1_CS PF18201.1 AIN97305.1 - 7.7e-10 39.1 0.0 5.4e-09 36.4 0.0 2.3 2 0 0 2 2 2 1 PIH1 CS-like domain Phage_Nu1 PF07471.12 AIN97305.1 - 0.31 10.8 6.2 0.85 9.4 6.2 1.7 1 0 0 1 1 1 0 Phage DNA packaging protein Nu1 MCRS_N PF13325.6 AIN97306.1 - 0.0035 17.4 0.0 0.0056 16.7 0.0 1.2 1 0 0 1 1 1 1 N-terminal region of micro-spherule protein Myb_DNA-binding PF00249.31 AIN97306.1 - 0.011 15.9 0.0 0.019 15.1 0.0 1.4 1 0 0 1 1 1 0 Myb-like DNA-binding domain Mito_carr PF00153.27 AIN97307.1 - 2.3e-32 110.8 6.3 2.6e-12 46.5 0.1 3.4 3 1 0 3 3 3 3 Mitochondrial carrier protein Acetyltransf_1 PF00583.25 AIN97308.1 - 1.1e-05 25.7 0.2 0.0015 18.8 0.0 2.7 3 0 0 3 3 3 2 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 AIN97308.1 - 0.011 16.2 0.1 0.16 12.4 0.0 2.3 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 AIN97308.1 - 0.088 12.9 0.0 0.18 11.9 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Phytochelatin PF05023.14 AIN97309.1 - 0.0034 16.6 0.0 15 4.7 0.0 4.1 4 0 0 4 4 4 2 Phytochelatin synthase AAA_lid_9 PF17871.1 AIN97309.1 - 0.37 10.8 1.5 0.95 9.4 0.0 2.2 2 0 0 2 2 2 0 AAA lid domain CDP-OH_P_transf PF01066.21 AIN97310.1 - 1.8e-21 76.7 0.1 1.8e-21 76.7 0.1 2.9 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase CTP_transf_like PF01467.26 AIN97310.1 - 1.2e-14 54.7 0.0 2.1e-14 53.9 0.0 1.4 1 0 0 1 1 1 1 Cytidylyltransferase-like zf-CCCH PF00642.24 AIN97311.1 - 0.00031 20.6 9.3 0.11 12.4 0.1 2.6 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Torus PF16131.5 AIN97311.1 - 0.0068 17.1 0.3 0.12 13.0 0.1 2.3 2 0 0 2 2 2 1 Torus domain zf-CCCH_2 PF14608.6 AIN97311.1 - 0.0095 16.4 8.2 0.95 10.0 0.4 2.8 2 0 0 2 2 2 2 RNA-binding, Nab2-type zinc finger zf-CCCH_4 PF18044.1 AIN97311.1 - 0.14 12.0 12.1 0.92 9.4 0.1 2.6 2 0 0 2 2 2 0 CCCH-type zinc finger zf_CCCH_4 PF18345.1 AIN97311.1 - 0.39 10.8 16.7 0.39 10.8 0.3 2.9 3 0 0 3 3 3 0 Zinc finger domain zf-CCCH_3 PF15663.5 AIN97311.1 - 0.41 10.9 4.6 11 6.3 1.1 2.6 2 0 0 2 2 2 0 Zinc-finger containing family zf-CCCH_4 PF18044.1 AIN97312.1 - 0.001 18.8 3.0 0.017 14.9 0.4 2.5 2 0 0 2 2 2 1 CCCH-type zinc finger zf-CCCH PF00642.24 AIN97312.1 - 0.0012 18.7 2.9 0.11 12.4 0.4 2.5 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Torus PF16131.5 AIN97312.1 - 0.084 13.6 4.7 0.29 11.8 0.1 2.7 2 0 0 2 2 2 0 Torus domain Opy2 PF09463.10 AIN97312.1 - 7.6 6.9 7.6 13 6.2 0.7 2.4 2 0 0 2 2 2 0 Opy2 protein HSP70 PF00012.20 AIN97314.1 - 1.9e-108 363.3 4.9 7.9e-103 344.7 0.0 2.6 3 0 0 3 3 3 2 Hsp70 protein FGGY_C PF02782.16 AIN97314.1 - 4.4e-06 26.6 1.2 0.00036 20.3 0.0 2.4 2 0 0 2 2 2 2 FGGY family of carbohydrate kinases, C-terminal domain MreB_Mbl PF06723.13 AIN97314.1 - 8.5e-05 21.5 0.0 0.00041 19.3 0.0 2.0 1 1 0 1 1 1 1 MreB/Mbl protein Herpes_U59 PF04529.12 AIN97314.1 - 0.013 14.6 0.5 1.1 8.3 0.1 2.2 2 0 0 2 2 2 0 Herpesvirus U59 protein E1_dh PF00676.20 AIN97315.1 - 2e-101 338.9 0.1 2.3e-101 338.7 0.1 1.0 1 0 0 1 1 1 1 Dehydrogenase E1 component DXP_synthase_N PF13292.6 AIN97315.1 - 0.012 14.8 0.4 0.039 13.1 0.0 1.8 2 0 0 2 2 2 0 1-deoxy-D-xylulose-5-phosphate synthase Med14 PF08638.11 AIN97316.1 - 0.045 13.2 0.2 0.077 12.4 0.2 1.3 1 0 0 1 1 1 0 Mediator complex subunit MED14 Ribosomal_L34e PF01199.18 AIN97317.1 - 2.6e-27 95.0 2.1 2.6e-27 95.0 2.1 2.2 2 1 0 2 2 2 1 Ribosomal protein L34e RecA PF00154.21 AIN97317.1 - 0.081 12.4 1.9 0.11 12.0 1.9 1.1 1 0 0 1 1 1 0 recA bacterial DNA recombination protein AAA_assoc_C PF09821.9 AIN97317.1 - 3.8 8.1 5.7 4.9 7.7 5.1 1.5 1 1 0 1 1 1 0 C-terminal AAA-associated domain PUF PF00806.19 AIN97319.1 - 8.9e-46 151.1 0.1 7.3e-06 25.4 0.0 8.6 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat DnaJ PF00226.31 AIN97320.1 - 5.6e-20 71.2 0.3 1.3e-19 70.1 0.3 1.7 1 0 0 1 1 1 1 DnaJ domain EF-hand_7 PF13499.6 AIN97321.1 - 4.5e-11 43.0 1.7 4.9e-07 30.1 0.9 2.5 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 AIN97321.1 - 1.6e-09 36.9 1.6 0.00011 21.9 0.0 3.8 4 0 0 4 4 4 2 EF-hand domain EF-hand_1 PF00036.32 AIN97321.1 - 6e-08 31.7 1.1 0.00083 18.7 0.1 3.6 3 0 0 3 3 3 2 EF hand EF-hand_8 PF13833.6 AIN97321.1 - 0.00011 21.9 5.6 0.1 12.4 0.0 3.4 3 1 1 4 4 4 2 EF-hand domain pair EF-hand_5 PF13202.6 AIN97321.1 - 0.0027 17.1 1.2 0.16 11.5 0.1 3.1 3 0 0 3 3 3 1 EF hand DUF3648 PF12364.8 AIN97322.1 - 5.3e-56 188.8 1.6 1.3e-55 187.5 1.6 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3648) WD40 PF00400.32 AIN97323.1 - 0.012 16.4 0.3 8.3 7.5 0.0 3.8 4 0 0 4 4 4 0 WD domain, G-beta repeat RAB3GAP2_N PF14655.6 AIN97323.1 - 0.21 10.8 1.2 8 5.6 0.0 2.9 3 0 0 3 3 3 0 Rab3 GTPase-activating protein regulatory subunit N-terminus NADH-G_4Fe-4S_3 PF10588.9 AIN97325.1 - 1.8e-15 56.2 0.3 1.8e-15 56.2 0.3 2.1 2 0 0 2 2 2 1 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region Fer2_4 PF13510.6 AIN97325.1 - 8.6e-12 45.0 0.1 2.5e-11 43.5 0.1 1.8 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer2 PF00111.27 AIN97325.1 - 4.1e-07 29.9 0.1 1e-06 28.6 0.1 1.7 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer4_7 PF12838.7 AIN97325.1 - 0.17 12.5 6.7 0.29 11.7 3.1 2.9 3 0 0 3 3 3 0 4Fe-4S dicluster domain Fer4_9 PF13187.6 AIN97325.1 - 0.44 10.8 5.9 0.31 11.3 2.4 2.3 2 0 0 2 2 2 0 4Fe-4S dicluster domain Fer4_6 PF12837.7 AIN97325.1 - 5.5 7.2 7.3 0.75 10.0 1.1 2.7 2 0 0 2 2 2 0 4Fe-4S binding domain DnaJ PF00226.31 AIN97326.1 - 9.4e-13 48.1 0.0 2e-12 47.0 0.0 1.5 1 1 0 1 1 1 1 DnaJ domain zf-CSL PF05207.13 AIN97326.1 - 1.9e-05 24.3 7.3 7.5e-05 22.4 7.3 1.9 1 1 0 1 1 1 1 CSL zinc finger E1-E2_ATPase PF00122.20 AIN97328.1 - 1.9e-45 154.6 4.7 2.3e-45 154.3 0.7 3.0 4 0 0 4 4 4 1 E1-E2 ATPase Hydrolase PF00702.26 AIN97328.1 - 1.5e-16 61.4 0.0 4.3e-16 59.8 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 AIN97328.1 - 1.1e-12 47.4 0.0 2.6e-12 46.2 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 AIN97328.1 - 4.8e-05 23.2 0.0 0.0004 20.2 0.2 2.1 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 AIN97328.1 - 0.023 14.8 0.0 0.045 13.8 0.0 1.4 1 0 0 1 1 1 0 Cation transport ATPase (P-type) YrvL PF14184.6 AIN97328.1 - 0.48 10.5 16.6 0.32 11.1 7.7 2.6 2 0 0 2 2 2 0 Regulatory protein YrvL Kinesin PF00225.23 AIN97329.1 - 4.8e-48 163.8 0.1 4.8e-48 163.8 0.1 1.8 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 AIN97329.1 - 1.9e-14 53.9 0.0 5.5e-14 52.3 0.0 1.8 1 0 0 1 1 1 1 Microtubule binding AAA_16 PF13191.6 AIN97329.1 - 0.037 14.4 0.0 0.037 14.4 0.0 3.3 3 0 0 3 3 3 0 AAA ATPase domain AAA_22 PF13401.6 AIN97329.1 - 0.064 13.5 1.9 0.17 12.2 0.0 2.7 2 1 1 3 3 3 0 AAA domain AAA_7 PF12775.7 AIN97329.1 - 0.066 12.7 0.0 0.15 11.6 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region RNA_helicase PF00910.22 AIN97329.1 - 0.11 13.0 0.0 0.24 11.8 0.0 1.6 1 0 0 1 1 1 0 RNA helicase DUF87 PF01935.17 AIN97329.1 - 1.8 8.6 0.0 1.8 8.6 0.0 2.9 3 0 0 3 3 3 0 Helicase HerA, central domain FAM76 PF16046.5 AIN97329.1 - 4.4 6.6 12.3 0.43 9.9 1.7 2.6 2 0 0 2 2 2 0 FAM76 protein BTB PF00651.31 AIN97330.1 - 1.5e-05 25.1 0.1 3.6e-05 24.0 0.1 1.6 1 0 0 1 1 1 1 BTB/POZ domain zf-C3HC4_3 PF13920.6 AIN97332.1 - 5.8e-14 51.7 13.3 7.7e-14 51.3 13.3 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 AIN97332.1 - 5.7e-06 26.1 13.8 8.5e-06 25.5 13.8 1.3 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 AIN97332.1 - 0.00032 20.9 16.9 0.0005 20.3 16.9 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 AIN97332.1 - 0.018 14.9 15.9 0.028 14.3 15.9 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) IU_nuc_hydro PF01156.19 AIN97333.1 - 3.6e-90 302.6 0.3 4.2e-90 302.4 0.3 1.0 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase Kinesin PF00225.23 AIN97335.1 - 3.1e-59 200.6 0.0 7.1e-59 199.4 0.0 1.6 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 AIN97335.1 - 2.9e-07 30.5 0.0 7.2e-07 29.2 0.0 1.6 1 1 0 1 1 1 1 Microtubule binding Noc2 PF03715.13 AIN97336.1 - 4.9e-87 292.0 1.2 4.9e-87 292.0 1.2 1.4 2 0 0 2 2 2 1 Noc2p family Nop14 PF04147.12 AIN97336.1 - 0.0053 15.0 21.7 0.16 10.2 0.2 2.2 2 0 0 2 2 2 2 Nop14-like family PTPA PF03095.15 AIN97336.1 - 0.043 13.3 1.7 5.2 6.4 0.1 2.7 3 0 0 3 3 3 0 Phosphotyrosyl phosphate activator (PTPA) protein YdjC PF04794.12 AIN97336.1 - 0.071 13.1 1.2 0.46 10.4 0.1 2.5 2 0 0 2 2 2 0 YdjC-like protein Isy1 PF06246.12 AIN97336.1 - 0.29 10.7 7.6 0.65 9.5 7.6 1.6 1 0 0 1 1 1 0 Isy1-like splicing family UPF0242 PF06785.11 AIN97336.1 - 1.3 9.1 12.6 0.11 12.6 0.3 2.3 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus DUF4375 PF14300.6 AIN97336.1 - 4.8 7.5 5.9 6.1 7.1 4.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4375) Got1 PF04178.12 AIN97337.1 - 7e-13 49.0 15.6 8.5e-13 48.7 15.6 1.1 1 0 0 1 1 1 1 Got1/Sft2-like family GCS PF03074.16 AIN97341.1 - 3.1e-140 467.7 0.0 4e-140 467.3 0.0 1.1 1 0 0 1 1 1 1 Glutamate-cysteine ligase DUF2239 PF09998.9 AIN97343.1 - 0.0014 18.4 1.7 0.0023 17.7 0.3 2.0 2 0 0 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2239) Use1 PF09753.9 AIN97343.1 - 0.052 13.3 17.8 0.014 15.2 10.8 2.6 1 1 1 2 2 2 0 Membrane fusion protein Use1 DUF5113 PF17140.4 AIN97343.1 - 0.13 12.1 0.2 0.26 11.1 0.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5113) XhlA PF10779.9 AIN97343.1 - 0.3 11.3 3.5 2.2 8.5 0.0 3.2 2 1 0 2 2 2 0 Haemolysin XhlA Syntaxin-6_N PF09177.11 AIN97343.1 - 0.48 11.0 7.3 0.3 11.7 1.0 2.7 1 1 0 2 2 2 0 Syntaxin 6, N-terminal DUF1759 PF03564.15 AIN97343.1 - 1.1 9.1 4.5 3.3 7.6 0.5 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF1759) TBCC_N PF16752.5 AIN97343.1 - 1.2 9.6 13.4 0.069 13.6 4.2 3.2 2 2 1 3 3 3 0 Tubulin-specific chaperone C N-terminal domain DUF948 PF06103.11 AIN97343.1 - 1.8 8.8 7.4 2.4 8.5 0.3 3.2 3 1 0 3 3 3 0 Bacterial protein of unknown function (DUF948) Fzo_mitofusin PF04799.13 AIN97343.1 - 3.3 7.2 7.7 11 5.5 1.6 2.5 2 0 0 2 2 2 0 fzo-like conserved region Agouti PF05039.12 AIN97343.1 - 4.9 7.9 6.4 1.9 9.3 1.0 2.8 2 1 1 3 3 3 0 Agouti protein TPR_MLP1_2 PF07926.12 AIN97343.1 - 5.5 7.1 17.6 4 7.5 0.9 3.0 2 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein SNARE PF05739.19 AIN97343.1 - 5.9 7.0 7.8 1.8 8.6 2.5 3.0 3 1 0 3 3 3 0 SNARE domain NPA PF16469.5 AIN97343.1 - 5.9 7.5 9.1 0.25 11.9 2.3 2.2 3 0 0 3 3 2 0 Nematode polyprotein allergen ABA-1 Rx_N PF18052.1 AIN97343.1 - 6.4 7.1 8.9 19 5.6 1.3 3.2 3 1 0 3 3 2 0 Rx N-terminal domain APG6_N PF17675.1 AIN97343.1 - 8.3 6.9 17.9 8.1 7.0 0.5 2.7 2 1 1 3 3 3 0 Apg6 coiled-coil region CK2S PF15011.6 AIN97343.1 - 9.8 6.0 13.2 0.7 9.8 1.6 3.0 2 1 1 3 3 3 0 Casein Kinase 2 substrate Ribosomal_S5_C PF03719.15 AIN97345.1 - 1.5e-24 85.2 0.0 2.4e-24 84.6 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain Ribosomal_S5 PF00333.20 AIN97345.1 - 6.5e-23 80.5 0.8 1.3e-22 79.5 0.8 1.5 1 0 0 1 1 1 1 Ribosomal protein S5, N-terminal domain FoP_duplication PF13865.6 AIN97345.1 - 0.094 13.3 7.7 0.2 12.2 7.7 1.5 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 SH3_9 PF14604.6 AIN97346.1 - 7.9e-09 35.2 0.0 1.5e-08 34.4 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 AIN97346.1 - 3e-07 29.9 0.0 6.1e-07 29.0 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 AIN97346.1 - 4e-05 23.2 0.0 9.5e-05 22.0 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain DUF1772 PF08592.11 AIN97346.1 - 0.0068 16.7 0.0 0.012 15.9 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1772) DnaJ PF00226.31 AIN97347.1 - 1.9e-19 69.5 0.5 8.8e-19 67.4 0.5 2.3 1 0 0 1 1 1 1 DnaJ domain DUF865 PF05906.11 AIN97347.1 - 0.02 14.7 0.4 0.037 13.8 0.4 1.4 1 0 0 1 1 1 0 Herpesvirus-7 repeat of unknown function (DUF865) HydF_tetramer PF18133.1 AIN97348.1 - 0.14 11.9 0.0 0.27 11.0 0.0 1.5 1 0 0 1 1 1 0 Hydrogen maturase F tetramerization domain CAMSAP_CC1 PF17095.5 AIN97348.1 - 0.17 11.8 0.3 0.17 11.8 0.3 3.4 5 0 0 5 5 5 0 Spectrin-binding region of Ca2+-Calmodulin DnaJ PF00226.31 AIN97348.1 - 7.3 6.8 7.7 2.3 8.4 0.8 2.9 3 1 0 3 3 3 0 DnaJ domain Fibrillarin PF01269.17 AIN97349.1 - 2.7e-99 330.9 0.0 3.1e-99 330.7 0.0 1.0 1 0 0 1 1 1 1 Fibrillarin GCD14 PF08704.10 AIN97349.1 - 9.3e-07 28.8 0.0 1.3e-06 28.3 0.0 1.1 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit Methyltr_RsmB-F PF01189.17 AIN97349.1 - 0.0064 16.1 0.0 0.0097 15.6 0.0 1.2 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F Lar_N PF09861.9 AIN97349.1 - 0.13 11.4 0.0 0.21 10.7 0.0 1.3 1 0 0 1 1 1 0 Lactate racemase N-terminal domain Clathrin_lg_ch PF01086.17 AIN97350.1 - 3.3e-11 43.7 0.1 3.7e-11 43.5 0.1 1.1 1 0 0 1 1 1 1 Clathrin light chain Globin PF00042.22 AIN97350.1 - 0.084 13.4 0.7 0.13 12.8 0.7 1.2 1 0 0 1 1 1 0 Globin mRNA_cap_C PF03919.15 AIN97350.1 - 0.14 12.8 0.5 0.18 12.4 0.5 1.2 1 0 0 1 1 1 0 mRNA capping enzyme, C-terminal domain NAM-associated PF14303.6 AIN97350.1 - 0.17 12.6 7.1 0.22 12.3 7.1 1.2 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain PRCC PF10253.9 AIN97350.1 - 1.8 9.3 11.8 2.4 8.9 11.8 1.1 1 0 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting SNARE PF05739.19 AIN97351.1 - 5.2e-09 36.0 4.0 7.1e-09 35.5 2.6 2.0 2 1 0 2 2 2 1 SNARE domain Laminin_II PF06009.12 AIN97351.1 - 0.018 15.1 4.2 0.42 10.6 0.6 2.9 2 1 1 3 3 3 0 Laminin Domain II Syntaxin_2 PF14523.6 AIN97351.1 - 0.045 14.1 6.9 0.21 12.0 0.1 2.6 2 1 0 2 2 2 0 Syntaxin-like protein UPF0242 PF06785.11 AIN97351.1 - 5.4 7.1 13.0 12 6.0 13.0 1.7 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DER1 PF04511.15 AIN97352.1 - 1.8e-33 116.1 8.6 2.1e-33 115.9 8.6 1.0 1 0 0 1 1 1 1 Der1-like family Pkinase PF00069.25 AIN97353.1 - 1.7e-49 168.6 0.0 2.9e-49 167.8 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 AIN97353.1 - 8.3e-25 87.5 0.0 5.1e-20 71.9 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase CAP_GLY PF01302.25 AIN97353.1 - 3.5e-16 59.0 0.5 7.2e-16 58.0 0.5 1.5 1 0 0 1 1 1 1 CAP-Gly domain Kinase-like PF14531.6 AIN97353.1 - 9.2e-05 21.9 0.0 0.032 13.5 0.0 2.2 2 0 0 2 2 2 2 Kinase-like Pkinase PF00069.25 AIN97354.1 - 8.8e-58 195.7 0.0 1e-57 195.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 AIN97354.1 - 2.9e-34 118.6 0.0 3.4e-34 118.3 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 AIN97354.1 - 2.5e-05 23.2 0.0 3.6e-05 22.7 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase ABC1 PF03109.16 AIN97354.1 - 0.0056 16.8 0.0 0.015 15.5 0.0 1.6 1 1 0 1 1 1 1 ABC1 family UPF0258 PF06789.12 AIN97354.1 - 0.15 12.1 0.0 0.25 11.5 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0258) Kinase-like PF14531.6 AIN97354.1 - 0.19 11.0 0.0 0.28 10.5 0.0 1.2 1 0 0 1 1 1 0 Kinase-like Peptidase_M24 PF00557.24 AIN97355.1 - 1.3e-21 77.3 0.5 1.8e-21 76.8 0.5 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 Pkinase PF00069.25 AIN97357.1 - 4.8e-71 239.2 0.0 5.9e-71 238.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 AIN97357.1 - 9.8e-31 107.0 0.1 3.3e-30 105.2 0.1 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 AIN97357.1 - 0.019 14.9 0.0 0.03 14.2 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family MYO10_CC PF16735.5 AIN97357.1 - 1.1 9.4 6.1 10 6.3 0.1 2.4 2 0 0 2 2 2 0 Unconventional myosin-X coiled coil domain HTH_3 PF01381.22 AIN97358.1 - 1.6e-11 44.0 0.2 2.7e-11 43.4 0.2 1.3 1 0 0 1 1 1 1 Helix-turn-helix MBF1 PF08523.10 AIN97358.1 - 7.4e-11 42.3 5.5 7.4e-11 42.3 5.5 1.6 2 0 0 2 2 2 1 Multiprotein bridging factor 1 HTH_31 PF13560.6 AIN97358.1 - 0.0011 19.3 0.6 0.002 18.4 0.6 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_19 PF12844.7 AIN97358.1 - 0.0022 17.9 0.1 0.0042 17.1 0.1 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_32 PF13565.6 AIN97358.1 - 0.0088 16.6 0.8 0.0088 16.6 0.8 1.9 2 0 0 2 2 2 1 Homeodomain-like domain HTH_37 PF13744.6 AIN97358.1 - 0.029 14.3 0.3 0.063 13.2 0.3 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain MqsA_antitoxin PF15731.5 AIN97358.1 - 0.038 14.1 0.4 0.057 13.5 0.4 1.4 1 1 0 1 1 1 0 Antitoxin component of bacterial toxin-antitoxin system, MqsA Mito_carr PF00153.27 AIN97359.1 - 7.9e-68 224.4 4.5 2.2e-24 85.2 0.1 3.0 2 1 1 3 3 3 3 Mitochondrial carrier protein Fuseless PF15993.5 AIN97359.1 - 0.0049 16.1 0.2 0.0086 15.3 0.2 1.3 1 0 0 1 1 1 1 Fuseless Mito_carr PF00153.27 AIN97360.1 - 8.1e-68 224.4 4.6 2.4e-24 85.1 0.1 3.0 2 1 1 3 3 3 3 Mitochondrial carrier protein Fuseless PF15993.5 AIN97360.1 - 0.0025 17.1 0.2 0.0043 16.3 0.2 1.3 1 0 0 1 1 1 1 Fuseless polyprenyl_synt PF00348.17 AIN97361.1 - 7.3e-52 176.0 0.0 1e-51 175.5 0.0 1.2 1 0 0 1 1 1 1 Polyprenyl synthetase CrtC PF07143.11 AIN97361.1 - 5.4e-16 59.7 0.0 5.8e-15 56.3 0.0 2.1 1 1 0 1 1 1 1 CrtC N-terminal lipocalin domain Lipocalin_9 PF17186.4 AIN97361.1 - 7e-12 45.7 0.0 1.3e-11 44.9 0.0 1.3 1 0 0 1 1 1 1 Lipocalin-like domain CDK5_activator PF03261.15 AIN97361.1 - 0.04 13.5 0.0 0.063 12.8 0.0 1.2 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein Complex1_LYR PF05347.15 AIN97362.1 - 3.6e-07 30.1 0.6 4.3e-06 26.7 0.0 3.1 3 0 0 3 3 3 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 AIN97362.1 - 0.008 16.9 0.5 0.008 16.9 0.5 3.0 3 1 1 4 4 4 1 Complex1_LYR-like GN3L_Grn1 PF08701.11 AIN97363.1 - 0.00017 21.6 14.8 0.00042 20.4 14.8 1.7 1 0 0 1 1 1 1 GNL3L/Grn1 putative GTPase UVR PF02151.19 AIN97364.1 - 1.4e-08 34.2 15.0 0.00032 20.3 7.0 2.6 2 0 0 2 2 2 2 UvrB/uvrC motif zf-Di19 PF05605.12 AIN97364.1 - 0.0018 18.5 3.0 0.0018 18.5 3.0 2.8 2 1 0 2 2 2 1 Drought induced 19 protein (Di19), zinc-binding HEAT PF02985.22 AIN97364.1 - 0.032 14.5 1.1 2 8.9 0.0 3.8 3 0 0 3 3 3 0 HEAT repeat HEAT_EZ PF13513.6 AIN97364.1 - 0.21 12.1 2.1 28 5.4 0.3 3.0 2 0 0 2 2 2 0 HEAT-like repeat zf-C2H2_4 PF13894.6 AIN97364.1 - 2.5 9.1 14.7 1.9 9.6 0.2 4.7 4 0 0 4 4 4 0 C2H2-type zinc finger Kinesin PF00225.23 AIN97365.1 - 3.3e-102 341.8 0.5 8e-102 340.6 0.0 1.8 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 AIN97365.1 - 5.2e-45 153.0 0.0 2.2e-44 151.0 0.0 2.2 1 0 0 1 1 1 1 Microtubule binding VHS PF00790.19 AIN97365.1 - 2.9e-05 23.9 0.1 0.00012 21.9 0.0 2.2 2 0 0 2 2 2 1 VHS domain Dor1 PF04124.12 AIN97365.1 - 0.00017 20.4 0.6 0.00031 19.5 0.6 1.4 1 0 0 1 1 1 1 Dor1-like family SRA1 PF07304.11 AIN97365.1 - 0.0097 15.7 0.0 0.028 14.2 0.0 1.7 1 0 0 1 1 1 1 Steroid receptor RNA activator (SRA1) NUDE_C PF04880.13 AIN97365.1 - 0.037 14.5 3.1 0.091 13.2 3.1 1.6 1 0 0 1 1 1 0 NUDE protein, C-terminal conserved region Atg14 PF10186.9 AIN97365.1 - 0.27 10.3 6.1 0.6 9.1 6.1 1.5 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF4407 PF14362.6 AIN97365.1 - 1.1 8.5 9.8 1.3 8.3 4.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Tup_N PF08581.10 AIN97365.1 - 1.5 9.2 11.0 1.6 9.1 6.5 2.8 2 0 0 2 2 2 0 Tup N-terminal DUF87 PF01935.17 AIN97365.1 - 3.8 7.5 7.8 33 4.5 0.1 3.7 3 0 0 3 3 3 0 Helicase HerA, central domain DUF5600 PF18150.1 AIN97367.1 - 6.5e-17 62.1 0.0 1.5e-16 60.9 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF5600) Dynamin_N PF00350.23 AIN97367.1 - 6e-15 55.7 0.0 2.2e-13 50.6 0.0 2.5 1 1 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.23 AIN97367.1 - 1.6e-07 31.4 0.0 3.7e-07 30.2 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase EHD_N PF16880.5 AIN97367.1 - 0.00019 21.2 0.8 0.00052 19.8 0.4 1.9 2 0 0 2 2 2 1 N-terminal EH-domain containing protein AAA_25 PF13481.6 AIN97367.1 - 0.032 13.8 0.0 0.14 11.8 0.0 2.0 1 1 0 1 1 1 0 AAA domain AAA_22 PF13401.6 AIN97367.1 - 0.052 13.8 0.0 9.9 6.4 0.0 3.2 4 0 0 4 4 4 0 AAA domain RsgA_GTPase PF03193.16 AIN97367.1 - 0.1 12.5 0.0 9.1 6.2 0.0 2.8 3 0 0 3 3 3 0 RsgA GTPase PapA_C PF16911.5 AIN97367.1 - 0.12 12.4 1.7 0.23 11.5 1.7 1.4 1 0 0 1 1 1 0 Phthiocerol/phthiodiolone dimycocerosyl transferase C-terminus cobW PF02492.19 AIN97367.1 - 0.18 11.4 0.0 8.6 5.9 0.0 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain U-box PF04564.15 AIN97369.1 - 0.0032 17.6 0.0 0.008 16.3 0.0 1.7 1 0 0 1 1 1 1 U-box domain zf-NOSIP PF15906.5 AIN97369.1 - 0.015 15.4 0.0 0.03 14.4 0.0 1.5 1 0 0 1 1 1 0 Zinc-finger of nitric oxide synthase-interacting protein zf_CCCH_4 PF18345.1 AIN97369.1 - 0.79 9.9 8.9 0.52 10.4 1.9 2.4 2 0 0 2 2 2 0 Zinc finger domain zf-CCCH PF00642.24 AIN97370.1 - 0.0006 19.7 6.1 0.0038 17.1 1.0 2.5 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) U-box PF04564.15 AIN97370.1 - 0.0064 16.6 0.0 0.014 15.5 0.0 1.5 1 0 0 1 1 1 1 U-box domain zf-NOSIP PF15906.5 AIN97370.1 - 0.022 14.9 0.0 0.048 13.8 0.0 1.6 1 0 0 1 1 1 0 Zinc-finger of nitric oxide synthase-interacting protein CorA PF01544.18 AIN97370.1 - 0.25 10.6 3.0 0.36 10.1 3.0 1.1 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein zf_CCCH_4 PF18345.1 AIN97370.1 - 1.4 9.1 8.0 0.11 12.6 2.7 2.0 2 0 0 2 2 2 0 Zinc finger domain Cep57_CLD_2 PF14197.6 AIN97370.1 - 1.5 9.0 6.4 7.9 6.6 6.4 2.0 1 1 0 1 1 1 0 Centrosome localisation domain of PPC89 UPF0016 PF01169.19 AIN97371.1 - 3.1e-43 146.0 20.2 4.5e-22 78.2 4.0 2.2 2 0 0 2 2 2 2 Uncharacterized protein family UPF0016 ABC_transp_aux PF09822.9 AIN97372.1 - 2.1e-06 27.4 0.0 3.8e-06 26.6 0.0 1.4 1 0 0 1 1 1 1 ABC-type uncharacterized transport system DUF4350 PF14258.6 AIN97372.1 - 0.00062 20.1 0.0 0.0064 16.9 0.0 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF4350) Coatomer_WDAD PF04053.14 AIN97373.1 - 0.0015 17.7 0.1 0.0061 15.7 0.0 2.0 3 0 0 3 3 3 1 Coatomer WD associated region WD40 PF00400.32 AIN97373.1 - 0.011 16.6 0.1 0.011 16.6 0.1 3.8 4 0 0 4 4 4 0 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 AIN97373.1 - 0.096 13.0 0.0 13 6.1 0.0 3.6 3 1 1 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain DUF1143 PF06608.11 AIN97374.1 - 0.0025 17.9 1.3 0.14 12.2 1.3 2.5 1 1 0 1 1 1 1 Protein of unknown function (DUF1143) Radical_SAM PF04055.21 AIN97375.1 - 1e-11 45.5 0.1 1.6e-11 44.9 0.1 1.3 1 0 0 1 1 1 1 Radical SAM superfamily LIAS_N PF16881.5 AIN97375.1 - 2.6e-09 37.5 0.0 7.2e-09 36.0 0.0 1.8 2 0 0 2 2 2 1 N-terminal domain of lipoyl synthase of Radical_SAM family Pkinase PF00069.25 AIN97376.1 - 3.3e-28 98.8 0.1 9.5e-17 61.2 0.0 3.8 3 1 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 AIN97376.1 - 2.1e-08 33.8 0.1 0.0038 16.6 0.0 2.7 3 0 0 3 3 3 2 Protein tyrosine kinase RIO1 PF01163.22 AIN97376.1 - 0.012 15.2 0.0 0.03 13.9 0.0 1.6 1 0 0 1 1 1 0 RIO1 family WD40 PF00400.32 AIN97378.1 - 3.3e-09 37.2 1.8 0.00049 20.9 0.1 5.5 5 0 0 5 5 5 2 WD domain, G-beta repeat PDZ_2 PF13180.6 AIN97378.1 - 0.00016 21.9 0.0 0.00041 20.6 0.0 1.7 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 AIN97378.1 - 0.0059 16.4 0.1 0.02 14.7 0.1 1.9 1 0 0 1 1 1 1 PDZ domain ANAPC4_WD40 PF12894.7 AIN97378.1 - 0.13 12.6 0.1 3.9 7.9 0.1 2.9 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain PAP2_3 PF14378.6 AIN97378.1 - 0.13 11.9 2.1 0.39 10.4 2.1 1.7 1 0 0 1 1 1 0 PAP2 superfamily Ribosomal_S13_N PF08069.12 AIN97379.1 - 8.4e-25 86.6 1.8 1.6e-24 85.7 1.8 1.5 1 0 0 1 1 1 1 Ribosomal S13/S15 N-terminal domain Ribosomal_S15 PF00312.22 AIN97379.1 - 1.9e-13 50.4 1.1 3.2e-13 49.7 1.1 1.3 1 0 0 1 1 1 1 Ribosomal protein S15 Synaptobrevin PF00957.21 AIN97380.1 - 4.8e-11 42.3 0.0 9.4e-11 41.4 0.0 1.5 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.6 AIN97380.1 - 0.069 13.2 0.0 0.2 11.7 0.0 1.7 2 0 0 2 2 2 0 Regulated-SNARE-like domain UMP1 PF05348.11 AIN97381.1 - 6e-05 23.3 0.0 7.2e-05 23.0 0.0 1.1 1 0 0 1 1 1 1 Proteasome maturation factor UMP1 TFIIS_C PF01096.18 AIN97382.1 - 2.8e-18 65.5 2.5 2.8e-18 65.5 2.5 2.4 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.16 AIN97382.1 - 4.9e-06 26.3 2.7 0.00015 21.6 0.6 2.4 2 0 0 2 2 2 1 RNA polymerases M/15 Kd subunit Zn_Tnp_IS1595 PF12760.7 AIN97382.1 - 0.00094 19.1 2.4 0.7 9.9 0.2 2.4 2 0 0 2 2 2 2 Transposase zinc-ribbon domain Baculo_LEF5_C PF11792.8 AIN97382.1 - 0.0078 15.9 0.1 0.022 14.4 0.1 1.8 1 0 0 1 1 1 1 Baculoviridae late expression factor 5 C-terminal domain B_solenoid_ydck PF18836.1 AIN97382.1 - 0.12 12.2 0.4 0.28 11.1 0.4 1.6 1 0 0 1 1 1 0 Beta solenoid repeat from YDCK TF_Zn_Ribbon PF08271.12 AIN97382.1 - 0.22 11.1 2.4 5.6 6.6 1.1 2.4 2 0 0 2 2 2 0 TFIIB zinc-binding zinc_ribbon_10 PF10058.9 AIN97382.1 - 0.76 9.6 4.5 9.9 6.0 0.1 3.2 3 0 0 3 3 3 0 Predicted integral membrane zinc-ribbon metal-binding protein NAP PF00956.18 AIN97384.1 - 1.4e-57 194.9 0.2 1.4e-57 194.9 0.2 1.7 2 0 0 2 2 2 1 Nucleosome assembly protein (NAP) BSP_II PF05432.11 AIN97384.1 - 0.0019 18.0 2.6 0.0019 18.0 2.6 2.0 3 0 0 3 3 3 1 Bone sialoprotein II (BSP-II) MgtE_N PF03448.17 AIN97384.1 - 0.0023 18.5 0.5 0.0062 17.1 0.5 1.7 1 0 0 1 1 1 1 MgtE intracellular N domain PGA2 PF07543.12 AIN97384.1 - 0.012 15.6 2.2 0.012 15.6 2.2 2.5 3 0 0 3 3 3 0 Protein trafficking PGA2 FRQ PF09421.10 AIN97384.1 - 0.046 11.8 0.6 0.068 11.2 0.6 1.2 1 0 0 1 1 1 0 Frequency clock protein DpnI_C PF17726.1 AIN97384.1 - 0.069 13.3 0.0 0.13 12.4 0.0 1.4 1 0 0 1 1 1 0 Dam-replacing HTH domain PBP1_TM PF14812.6 AIN97384.1 - 6.2 7.3 12.3 1.5 9.2 0.8 3.2 4 0 0 4 4 4 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Uso1_p115_C PF04871.13 AIN97385.1 - 0.016 15.5 0.5 0.032 14.6 0.5 1.4 1 0 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region CCDC53 PF10152.9 AIN97386.1 - 1.3e-45 155.5 0.0 1.7e-45 155.2 0.0 1.1 1 0 0 1 1 1 1 Subunit CCDC53 of WASH complex UPF0193 PF05250.11 AIN97390.1 - 0.0019 18.1 0.9 0.0033 17.2 0.9 1.4 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0193) PilJ PF13675.6 AIN97390.1 - 0.02 14.9 2.7 0.031 14.3 0.7 2.2 3 0 0 3 3 3 0 Type IV pili methyl-accepting chemotaxis transducer N-term P22_CoatProtein PF11651.8 AIN97390.1 - 0.26 9.9 0.0 0.38 9.3 0.0 1.1 1 0 0 1 1 1 0 P22 coat protein - gene protein 5 RPAP1_N PF08621.10 AIN97390.1 - 6.8 6.6 9.4 1.6 8.6 0.2 2.9 3 0 0 3 3 3 0 RPAP1-like, N-terminal SAP PF02037.27 AIN97391.1 - 0.1 12.4 0.0 0.6 9.9 0.0 2.3 2 0 0 2 2 2 0 SAP domain LRR_8 PF13855.6 AIN97393.1 - 4.2e-07 29.6 0.6 0.015 15.1 0.0 2.4 2 0 0 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 AIN97393.1 - 7.6e-06 26.2 0.2 0.11 13.0 0.0 3.7 2 1 4 6 6 6 4 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 AIN97393.1 - 0.0042 16.6 0.0 0.32 10.5 0.0 2.3 1 1 0 2 2 2 2 Leucine-rich repeat Peptidase_M24 PF00557.24 AIN97394.1 - 1.2e-47 162.4 0.1 1.7e-47 161.9 0.1 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 zf-C6H2 PF15801.5 AIN97394.1 - 1.6e-14 53.9 8.5 3.5e-14 52.8 8.5 1.5 1 0 0 1 1 1 1 zf-MYND-like zinc finger, mRNA-binding zf-MYND PF01753.18 AIN97394.1 - 4.2e-05 23.5 5.6 9e-05 22.5 5.6 1.6 1 0 0 1 1 1 1 MYND finger CH_2 PF06294.11 AIN97395.1 - 1.2e-18 67.0 0.0 2.4e-18 66.0 0.0 1.6 1 0 0 1 1 1 1 CH-like domain in sperm protein TBCC PF07986.12 AIN97397.1 - 2.3e-23 82.2 14.3 1.1e-08 34.8 0.0 3.4 3 0 0 3 3 3 3 Tubulin binding cofactor C Pkinase PF00069.25 AIN97398.1 - 9e-44 149.8 0.0 1e-32 113.6 0.0 3.2 3 0 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.17 AIN97398.1 - 1.6e-14 53.8 0.0 2.8e-13 49.8 0.0 2.3 2 0 0 2 2 2 1 Protein tyrosine kinase DAG1 PF05454.11 AIN97400.1 - 5.4e-05 22.7 1.0 5.9e-05 22.6 1.0 1.1 1 0 0 1 1 1 1 Dystroglycan (Dystrophin-associated glycoprotein 1) DUF5493 PF17597.2 AIN97400.1 - 0.0071 16.6 0.3 0.011 16.0 0.1 1.4 1 1 1 2 2 2 1 Family of unknown function (DUF5493) DUF4118 PF13493.6 AIN97400.1 - 0.013 15.3 3.0 0.018 14.8 3.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4118) Mid2 PF04478.12 AIN97400.1 - 0.03 14.2 0.3 0.037 13.9 0.3 1.1 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor CYTH PF01928.21 AIN97401.1 - 2.2e-13 50.5 0.1 4e-05 23.6 0.0 3.8 4 0 0 4 4 4 2 CYTH domain Histone PF00125.24 AIN97402.1 - 7.8e-39 133.0 5.3 9.7e-39 132.7 5.3 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 AIN97402.1 - 1.7e-07 31.4 1.3 4.8e-07 30.0 0.0 2.0 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-T_C PF15511.6 AIN97402.1 - 2.9e-05 24.1 1.5 3.9e-05 23.7 0.1 1.8 2 0 0 2 2 2 1 Centromere kinetochore component CENP-T histone fold MIP-T3 PF10243.9 AIN97402.1 - 0.084 12.9 0.1 0.4 10.7 0.0 1.9 2 0 0 2 2 2 0 Microtubule-binding protein MIP-T3 CH-like domain DUF2294 PF10057.9 AIN97402.1 - 0.11 12.6 0.5 0.16 12.1 0.1 1.4 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2294) ANF_receptor PF01094.28 AIN97403.1 - 1.4e-38 132.9 7.1 5.4e-29 101.4 1.7 2.9 2 1 0 2 2 2 2 Receptor family ligand binding region Peripla_BP_6 PF13458.6 AIN97403.1 - 2.5e-09 37.3 9.0 4.8e-06 26.5 2.7 2.8 2 1 0 2 2 2 2 Periplasmic binding protein Glucodextran_C PF09985.9 AIN97403.1 - 0.01 15.3 0.0 0.66 9.4 0.0 2.3 2 0 0 2 2 2 0 C-terminal binding-module, SLH-like, of glucodextranase RNA_pol_A_bac PF01000.26 AIN97405.1 - 1.2e-19 70.8 0.0 2.4e-19 69.8 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.24 AIN97405.1 - 8.4e-15 54.0 0.0 1.2e-14 53.4 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Fer4_9 PF13187.6 AIN97405.1 - 0.0059 16.7 0.4 0.013 15.6 0.4 1.5 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_7 PF12838.7 AIN97405.1 - 0.026 15.1 0.4 0.078 13.6 0.4 1.8 1 0 0 1 1 1 0 4Fe-4S dicluster domain ETF_QO PF05187.13 AIN97405.1 - 0.046 13.9 0.6 0.44 10.7 0.1 2.2 1 1 1 2 2 2 0 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S Fer4_10 PF13237.6 AIN97405.1 - 0.05 13.7 0.3 0.14 12.3 0.3 1.7 1 0 0 1 1 1 0 4Fe-4S dicluster domain Fer4_6 PF12837.7 AIN97405.1 - 0.92 9.7 2.6 2.1 8.6 0.9 2.3 2 0 0 2 2 2 0 4Fe-4S binding domain Utp11 PF03998.13 AIN97406.1 - 2e-30 106.5 35.2 2.5e-28 99.7 35.2 2.1 1 1 0 1 1 1 1 Utp11 protein Kinesin PF00225.23 AIN97407.1 - 7.3e-91 304.5 0.0 3.3e-90 302.4 0.0 2.2 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 AIN97407.1 - 4e-15 56.0 0.0 4.8e-10 39.6 0.0 3.1 3 0 0 3 3 3 2 Microtubule binding DUF664 PF04978.12 AIN97407.1 - 0.00017 22.0 4.3 0.00017 22.0 4.3 3.6 2 1 1 3 3 3 1 Protein of unknown function (DUF664) SAP PF02037.27 AIN97409.1 - 0.22 11.3 0.2 0.22 11.3 0.2 4.0 4 0 0 4 4 4 0 SAP domain DUF4347 PF14252.6 AIN97409.1 - 0.45 10.4 4.0 0.45 10.3 0.7 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4347) DUF948 PF06103.11 AIN97409.1 - 1.3 9.4 12.1 0.35 11.2 0.2 4.9 4 1 1 5 5 5 0 Bacterial protein of unknown function (DUF948) Kinesin PF00225.23 AIN97410.1 - 3.2e-92 309.0 12.7 3.3e-76 256.4 0.3 4.9 4 0 0 4 4 4 3 Kinesin motor domain Microtub_bd PF16796.5 AIN97410.1 - 3.3e-14 53.1 5.4 1.2e-08 35.0 0.0 4.7 5 0 0 5 5 5 2 Microtubule binding Kinesin_assoc PF16183.5 AIN97410.1 - 0.00021 21.5 9.2 0.00021 21.5 9.2 10.2 3 3 3 8 8 8 1 Kinesin-associated Pox_A_type_inc PF04508.12 AIN97410.1 - 0.16 11.9 7.3 0.57 10.1 0.3 5.5 6 0 0 6 6 6 0 Viral A-type inclusion protein repeat Pedibin PF08182.11 AIN97410.1 - 0.6 10.0 5.3 10 6.0 0.2 4.0 3 0 0 3 3 3 0 Pedibin/Hym-346 family DUF4988 PF16378.5 AIN97410.1 - 4.6 6.9 7.3 4.2 7.0 0.1 3.2 3 0 0 3 3 3 0 Domain of unknown function Ldh_1_N PF00056.23 AIN97411.1 - 1.5e-35 122.3 0.3 2.3e-35 121.7 0.3 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.18 AIN97411.1 - 5.3e-35 120.8 0.0 7.9e-35 120.2 0.0 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain 3Beta_HSD PF01073.19 AIN97411.1 - 0.0055 15.7 0.0 0.054 12.5 0.0 2.0 1 1 1 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family DUF1664 PF07889.12 AIN97412.1 - 1.1e-05 25.4 13.3 0.032 14.3 1.2 3.5 1 1 3 4 4 4 2 Protein of unknown function (DUF1664) Baculo_PEP_C PF04513.12 AIN97412.1 - 2e-05 24.7 10.9 0.15 12.1 1.0 3.5 1 1 2 3 3 3 2 Baculovirus polyhedron envelope protein, PEP, C terminus TPR_MLP1_2 PF07926.12 AIN97412.1 - 3.3e-05 24.0 16.7 3.4e-05 23.9 1.8 3.5 2 1 2 4 4 4 1 TPR/MLP1/MLP2-like protein Spc7 PF08317.11 AIN97412.1 - 0.00025 20.0 16.0 0.053 12.4 0.3 2.3 1 1 2 3 3 3 3 Spc7 kinetochore protein GAS PF13851.6 AIN97412.1 - 0.00029 20.2 6.0 0.00029 20.2 6.0 2.6 1 1 0 2 2 2 1 Growth-arrest specific micro-tubule binding Fez1 PF06818.15 AIN97412.1 - 0.00049 20.6 18.7 0.0079 16.7 11.6 2.5 1 1 1 2 2 2 1 Fez1 DUF948 PF06103.11 AIN97412.1 - 0.0017 18.6 8.8 0.69 10.2 0.1 4.3 2 1 1 3 3 3 1 Bacterial protein of unknown function (DUF948) Fib_alpha PF08702.10 AIN97412.1 - 0.0017 18.6 6.9 1.7 8.9 0.2 3.5 2 1 1 3 3 3 2 Fibrinogen alpha/beta chain family IFT57 PF10498.9 AIN97412.1 - 0.0021 17.1 9.3 0.01 14.8 4.3 2.3 1 1 1 2 2 2 1 Intra-flagellar transport protein 57 ThiD2 PF17792.1 AIN97412.1 - 0.0076 16.7 14.0 0.053 14.0 7.2 2.4 1 1 1 2 2 2 1 ThiD2 family Laminin_II PF06009.12 AIN97412.1 - 0.0078 16.2 12.8 0.022 14.8 0.5 3.6 2 1 2 4 4 4 1 Laminin Domain II Leu_zip PF15294.6 AIN97412.1 - 0.008 15.7 9.7 0.015 14.8 0.9 2.9 1 1 2 3 3 3 1 Leucine zipper AKNA PF12443.8 AIN97412.1 - 0.011 16.4 1.3 0.043 14.5 0.6 2.4 1 1 1 2 2 1 0 AT-hook-containing transcription factor BAR_3 PF16746.5 AIN97412.1 - 0.011 15.4 5.3 0.44 10.2 0.0 2.5 1 1 1 2 2 2 0 BAR domain of APPL family Alanine_zipper PF11839.8 AIN97412.1 - 0.016 15.6 6.7 0.016 15.6 6.7 3.4 4 0 0 4 4 2 0 Alanine-zipper, major outer membrane lipoprotein Tektin PF03148.14 AIN97412.1 - 0.016 14.0 14.5 0.27 9.9 0.1 3.1 1 1 0 2 2 2 0 Tektin family ApoLp-III PF07464.11 AIN97412.1 - 0.019 15.0 3.2 0.099 12.7 0.2 2.8 1 1 2 3 3 3 0 Apolipophorin-III precursor (apoLp-III) BLOC1_2 PF10046.9 AIN97412.1 - 0.02 15.2 9.1 6.9 7.1 0.6 4.7 2 1 3 5 5 5 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 LOH1CR12 PF10158.9 AIN97412.1 - 0.029 14.4 3.7 0.72 9.9 0.1 3.1 1 1 1 3 3 3 0 Tumour suppressor protein RmuC PF02646.16 AIN97412.1 - 0.048 12.8 11.8 0.099 11.8 0.4 3.5 1 1 1 3 3 3 0 RmuC family CorA PF01544.18 AIN97412.1 - 0.062 12.6 11.7 1.3 8.2 5.1 2.5 1 1 0 2 2 2 0 CorA-like Mg2+ transporter protein Bacillus_HBL PF05791.11 AIN97412.1 - 0.078 12.8 5.8 1 9.1 1.2 3.0 2 1 1 3 3 3 0 Bacillus haemolytic enterotoxin (HBL) Peptidase_M32 PF02074.15 AIN97412.1 - 0.08 11.7 3.6 0.11 11.2 3.6 1.3 1 0 0 1 1 1 0 Carboxypeptidase Taq (M32) metallopeptidase SepF PF04472.12 AIN97412.1 - 0.08 13.2 0.5 1.9 8.8 0.1 2.7 2 1 0 2 2 2 0 Cell division protein SepF Collagen_mid PF15984.5 AIN97412.1 - 0.1 12.3 0.0 0.31 10.8 0.0 1.7 1 1 0 1 1 1 0 Bacterial collagen, middle region betaPIX_CC PF16523.5 AIN97412.1 - 0.11 12.3 5.4 0.42 10.5 1.6 3.2 2 1 0 2 2 2 0 betaPIX coiled coil V_ATPase_I PF01496.19 AIN97412.1 - 0.11 10.4 7.3 0.067 11.1 5.5 1.5 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family Prefoldin_2 PF01920.20 AIN97412.1 - 0.13 12.3 11.6 0.77 9.7 2.1 4.0 2 2 2 4 4 4 0 Prefoldin subunit Tropomyosin_1 PF12718.7 AIN97412.1 - 0.13 12.4 17.2 2.2 8.4 12.2 3.2 1 1 2 3 3 3 0 Tropomyosin like TMP_2 PF06791.13 AIN97412.1 - 0.13 11.9 3.9 0.062 13.0 0.6 2.0 2 0 0 2 2 2 0 Prophage tail length tape measure protein Exonuc_VII_L PF02601.15 AIN97412.1 - 0.14 11.7 16.5 37 3.7 16.5 2.2 1 1 0 1 1 1 0 Exonuclease VII, large subunit COG2 PF06148.11 AIN97412.1 - 0.15 12.2 15.1 5.1 7.2 0.2 4.1 1 1 3 4 4 4 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF1043 PF06295.12 AIN97412.1 - 0.15 12.0 7.4 1.1 9.2 0.2 3.7 2 1 2 4 4 4 0 Protein of unknown function (DUF1043) Atg14 PF10186.9 AIN97412.1 - 0.16 11.0 11.1 0.95 8.5 9.9 2.3 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 Syntaxin_2 PF14523.6 AIN97412.1 - 0.18 12.2 15.0 1.6 9.2 2.2 3.5 2 2 0 2 2 2 0 Syntaxin-like protein FAM76 PF16046.5 AIN97412.1 - 0.21 10.9 8.8 1.4 8.3 4.0 2.3 1 1 1 2 2 2 0 FAM76 protein ZYG-11_interact PF05884.12 AIN97412.1 - 0.22 10.9 2.0 0.33 10.3 0.6 1.9 1 1 1 2 2 2 0 Interactor of ZYG-11 TMF_TATA_bd PF12325.8 AIN97412.1 - 0.24 11.6 18.3 0.15 12.3 6.4 3.5 2 2 1 3 3 3 0 TATA element modulatory factor 1 TATA binding TMPIT PF07851.13 AIN97412.1 - 0.28 10.4 7.6 1.8 7.8 0.9 2.9 1 1 2 3 3 3 0 TMPIT-like protein DUF4795 PF16043.5 AIN97412.1 - 0.29 10.7 16.1 0.89 9.1 8.2 2.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4795) Syntaxin-6_N PF09177.11 AIN97412.1 - 0.31 11.6 11.3 5.5e+02 1.2 11.3 3.9 1 1 0 1 1 1 0 Syntaxin 6, N-terminal PhaP_Bmeg PF09602.10 AIN97412.1 - 0.38 10.7 5.2 0.38 10.7 1.2 2.6 1 1 0 1 1 1 0 Polyhydroxyalkanoic acid inclusion protein (PhaP_Bmeg) Phage_GPO PF05929.11 AIN97412.1 - 0.42 10.2 13.8 1.3 8.6 1.6 2.6 1 1 2 3 3 3 0 Phage capsid scaffolding protein (GPO) serine peptidase Prominin PF05478.11 AIN97412.1 - 0.43 8.5 4.1 0.89 7.4 3.9 1.6 1 1 0 1 1 1 0 Prominin CREPT PF16566.5 AIN97412.1 - 0.46 10.6 12.5 0.36 11.0 2.9 3.3 1 1 2 3 3 3 0 Cell-cycle alteration and expression-elevated protein in tumour DUF2721 PF11026.8 AIN97412.1 - 0.55 10.1 15.1 1.6 8.6 0.1 4.2 2 1 2 4 4 4 0 Protein of unknown function (DUF2721) DUF5340 PF17275.2 AIN97412.1 - 0.57 10.3 3.4 0.84 9.8 0.2 2.6 3 0 0 3 3 2 0 Family of unknown function (DUF5340) FadA PF09403.10 AIN97412.1 - 0.62 10.6 10.0 1.3 9.5 2.3 3.6 2 1 1 3 3 3 0 Adhesion protein FadA HlyD_2 PF12700.7 AIN97412.1 - 0.65 8.7 2.2 0.47 9.1 0.6 1.5 2 0 0 2 2 2 0 HlyD family secretion protein DUF745 PF05335.13 AIN97412.1 - 0.71 9.6 18.6 0.16 11.6 5.1 3.7 1 1 3 4 4 4 0 Protein of unknown function (DUF745) AAA_27 PF13514.6 AIN97412.1 - 0.74 9.4 11.5 0.14 11.8 0.8 3.1 1 1 2 3 3 3 0 AAA domain zf-C4H2 PF10146.9 AIN97412.1 - 0.85 9.9 11.6 4.3 7.6 8.1 2.3 1 1 1 2 2 2 0 Zinc finger-containing protein FH2 PF02181.23 AIN97412.1 - 1.3 8.1 5.5 3.9 6.5 4.2 2.4 1 1 0 1 1 1 0 Formin Homology 2 Domain GCN5L1 PF06320.13 AIN97412.1 - 1.3 9.2 10.5 25 5.1 0.2 3.6 1 1 4 5 5 5 0 GCN5-like protein 1 (GCN5L1) DUF4407 PF14362.6 AIN97412.1 - 1.7 7.9 22.8 1.5 8.1 4.3 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) Ran-binding PF05508.11 AIN97412.1 - 2 7.3 6.9 0.33 9.9 0.9 2.5 1 1 1 3 3 3 0 RanGTP-binding protein Seryl_tRNA_N PF02403.22 AIN97412.1 - 2.2 8.6 15.2 31 4.8 7.3 3.7 2 1 2 4 4 4 0 Seryl-tRNA synthetase N-terminal domain YabA PF06156.13 AIN97412.1 - 2.3 8.9 9.6 27 5.5 0.2 3.2 2 2 0 2 2 2 0 Initiation control protein YabA DUF724 PF05266.14 AIN97412.1 - 2.7 7.8 11.4 2.7 7.8 0.2 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF724) DUF2730 PF10805.8 AIN97412.1 - 3.1 8.0 4.9 4.7 7.4 0.2 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF2730) DUF3347 PF11827.8 AIN97412.1 - 3.2 7.9 7.0 1.5 9.0 1.0 2.7 1 1 1 3 3 3 0 Protein of unknown function (DUF3347) APG6_N PF17675.1 AIN97412.1 - 3.3 8.3 19.8 2.2 8.8 5.2 3.3 2 1 1 3 3 3 0 Apg6 coiled-coil region PhageMin_Tail PF10145.9 AIN97412.1 - 4.2 7.2 8.7 91 2.8 8.8 3.1 1 1 0 1 1 1 0 Phage-related minor tail protein Methyltransf_11 PF08241.12 AIN97413.1 - 2.6e-12 47.2 0.0 5.9e-12 46.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 AIN97413.1 - 3.3e-11 43.8 0.0 6.5e-11 42.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 AIN97413.1 - 8.7e-11 42.5 0.0 1.7e-10 41.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 AIN97413.1 - 1.8e-06 27.9 0.0 3.6e-06 26.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 AIN97413.1 - 1.3e-05 25.1 0.0 2.5e-05 24.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.15 AIN97413.1 - 0.0013 18.7 0.0 0.0023 17.8 0.0 1.4 1 0 0 1 1 1 1 Hypothetical methyltransferase Ubie_methyltran PF01209.18 AIN97413.1 - 0.0014 18.0 0.0 0.0021 17.5 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Vps36_ESCRT-II PF11605.8 AIN97414.1 - 4e-24 84.6 0.0 6.9e-24 83.8 0.0 1.4 1 0 0 1 1 1 1 Vacuolar protein sorting protein 36 Vps36 EAP30 PF04157.16 AIN97414.1 - 1.5e-23 83.3 0.1 2e-23 82.9 0.1 1.2 1 0 0 1 1 1 1 EAP30/Vps36 family Ribosomal_S25 PF03297.15 AIN97414.1 - 0.0068 16.6 0.0 0.014 15.6 0.0 1.5 1 0 0 1 1 1 1 S25 ribosomal protein PhnJ PF06007.11 AIN97414.1 - 0.025 13.6 0.0 0.04 12.9 0.0 1.2 1 0 0 1 1 1 0 Phosphonate metabolism protein PhnJ IRS PF02174.17 AIN97414.1 - 0.08 12.8 0.0 0.17 11.8 0.0 1.5 1 0 0 1 1 1 0 PTB domain (IRS-1 type) Rsm22 PF09243.10 AIN97415.1 - 0.0097 15.2 0.0 0.018 14.3 0.0 1.4 1 0 0 1 1 1 1 Mitochondrial small ribosomal subunit Rsm22 Mem_trans PF03547.18 AIN97416.1 - 2.7e-22 78.7 7.1 1.6e-21 76.2 7.1 2.1 1 1 0 1 1 1 1 Membrane transport protein V-SNARE_C PF12352.8 AIN97417.1 - 1.2e-10 41.5 3.4 1.2e-10 41.5 3.4 2.7 3 0 0 3 3 3 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.13 AIN97417.1 - 2.8e-06 27.2 0.7 1.1e-05 25.3 0.0 2.2 3 0 0 3 3 3 1 Sec20 DUF572 PF04502.13 AIN97417.1 - 0.018 14.7 3.4 1.1 8.8 0.1 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF572) PLU-1 PF08429.11 AIN97417.1 - 0.054 12.7 1.9 1.3 8.1 0.4 2.1 2 0 0 2 2 2 0 PLU-1-like protein DUF5082 PF16888.5 AIN97417.1 - 0.075 13.3 2.7 3.3 8.0 0.0 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF5082) UPF0029 PF01205.19 AIN97417.1 - 0.093 13.1 0.1 0.18 12.2 0.1 1.5 1 1 0 1 1 1 0 Uncharacterized protein family UPF0029 Prefoldin PF02996.17 AIN97417.1 - 0.13 12.2 5.5 3.5 7.6 0.1 2.7 2 1 0 2 2 2 0 Prefoldin subunit Fib_alpha PF08702.10 AIN97417.1 - 0.7 10.1 3.0 0.7 10.1 1.2 1.9 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family ATG16 PF08614.11 AIN97417.1 - 3.1 8.0 16.1 1.5 9.0 12.8 1.8 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) RasGAP_C PF03836.15 AIN97417.1 - 5.8 7.1 10.1 13 6.0 6.8 2.5 2 1 1 3 3 3 0 RasGAP C-terminus DUF3450 PF11932.8 AIN97417.1 - 9.3 5.5 13.3 3.4 6.9 5.4 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF3450) SRP_TPR_like PF17004.5 AIN97419.1 - 1.5e-11 44.3 4.8 1.5e-11 44.3 4.8 2.9 3 1 0 3 3 3 1 Putative TPR-like repeat SRP72 PF08492.12 AIN97419.1 - 1.2e-07 32.0 0.9 1.2e-07 32.0 0.9 2.9 2 0 0 2 2 2 1 SRP72 RNA-binding domain ANAPC3 PF12895.7 AIN97419.1 - 2.7e-07 30.7 18.4 1.2e-05 25.4 7.5 5.0 4 1 1 5 5 5 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.6 AIN97419.1 - 0.0043 17.5 40.8 0.39 11.3 1.8 8.0 5 2 3 9 9 9 4 Tetratricopeptide repeat TPR_6 PF13174.6 AIN97419.1 - 0.013 16.1 19.7 5.6 7.8 0.1 7.0 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_2 PF07719.17 AIN97419.1 - 0.015 15.4 22.2 2.5 8.4 0.3 6.0 6 0 0 6 6 5 0 Tetratricopeptide repeat TPR_8 PF13181.6 AIN97419.1 - 0.033 14.4 10.0 6.8 7.2 0.8 5.3 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_17 PF13431.6 AIN97419.1 - 0.058 13.8 8.9 44 4.8 0.1 5.4 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_16 PF13432.6 AIN97419.1 - 0.099 13.3 42.7 0.42 11.3 0.1 8.1 7 2 1 8 8 7 0 Tetratricopeptide repeat TPR_1 PF00515.28 AIN97419.1 - 2.1 8.3 13.3 8.1 6.5 0.2 4.5 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.6 AIN97419.1 - 6.3 7.9 46.5 2.7 9.1 3.1 9.8 6 3 4 10 10 9 0 Tetratricopeptide repeat ABC_tran PF00005.27 AIN97420.1 - 5.5e-42 143.5 0.0 2.6e-20 73.4 0.0 2.9 3 0 0 3 3 2 2 ABC transporter ABC_tran_Xtn PF12848.7 AIN97420.1 - 2.3e-23 82.0 5.5 5.7e-22 77.5 2.3 2.5 2 0 0 2 2 2 1 ABC transporter AAA_21 PF13304.6 AIN97420.1 - 1.8e-21 77.3 0.3 1.2e-05 25.3 0.0 4.2 3 1 1 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 AIN97420.1 - 2.6e-11 43.4 1.4 0.0026 17.2 0.0 4.4 4 1 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_33 PF13671.6 AIN97420.1 - 1.7e-07 31.5 0.0 0.045 13.9 0.0 3.3 3 0 0 3 3 3 2 AAA domain AAA_28 PF13521.6 AIN97420.1 - 2.6e-07 31.0 0.0 0.0093 16.2 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_23 PF13476.6 AIN97420.1 - 4e-07 30.8 5.9 0.032 14.8 0.0 3.6 4 0 0 4 4 3 2 AAA domain AAA_16 PF13191.6 AIN97420.1 - 1.1e-06 29.2 0.0 0.0087 16.5 0.0 2.5 2 0 0 2 2 2 2 AAA ATPase domain AAA PF00004.29 AIN97420.1 - 1.6e-06 28.6 0.0 0.0084 16.5 0.0 3.1 3 1 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 AIN97420.1 - 3.8e-06 27.2 0.1 0.017 15.5 0.0 3.3 3 0 0 3 3 3 1 RNA helicase AAA_18 PF13238.6 AIN97420.1 - 4.2e-06 27.3 0.0 0.062 13.8 0.0 3.1 3 0 0 3 3 2 2 AAA domain AAA_29 PF13555.6 AIN97420.1 - 1.2e-05 25.0 0.0 0.22 11.3 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.6 AIN97420.1 - 2.9e-05 24.3 0.2 0.034 14.4 0.0 2.9 2 1 0 2 2 2 1 AAA domain AAA_15 PF13175.6 AIN97420.1 - 3.5e-05 23.7 4.7 0.41 10.3 0.0 3.9 4 0 0 4 4 4 2 AAA ATPase domain AAA_5 PF07728.14 AIN97420.1 - 4e-05 23.6 0.1 0.04 13.9 0.0 2.6 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) RsgA_GTPase PF03193.16 AIN97420.1 - 4.1e-05 23.5 0.0 0.26 11.2 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase TsaE PF02367.17 AIN97420.1 - 8.9e-05 22.5 0.1 0.005 16.8 0.0 2.9 2 1 1 3 3 3 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE NACHT PF05729.12 AIN97420.1 - 0.0001 22.2 0.1 0.19 11.7 0.0 2.8 3 0 0 3 3 3 1 NACHT domain AAA_14 PF13173.6 AIN97420.1 - 0.00011 22.2 0.0 2.3 8.3 0.0 3.9 4 0 0 4 4 4 2 AAA domain AAA_25 PF13481.6 AIN97420.1 - 0.00019 21.1 0.0 0.58 9.7 0.0 3.3 2 1 0 2 2 2 2 AAA domain AAA_24 PF13479.6 AIN97420.1 - 0.00021 21.1 0.0 0.088 12.5 0.0 2.9 3 0 0 3 3 3 1 AAA domain AAA_7 PF12775.7 AIN97420.1 - 0.00048 19.7 0.0 0.11 12.0 0.0 2.4 2 0 0 2 2 2 1 P-loop containing dynein motor region MMR_HSR1 PF01926.23 AIN97420.1 - 0.00081 19.5 0.0 1.3 9.1 0.0 2.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase Rad17 PF03215.15 AIN97420.1 - 0.00084 19.3 0.1 0.37 10.7 0.0 2.5 2 0 0 2 2 2 1 Rad17 P-loop domain NB-ARC PF00931.22 AIN97420.1 - 0.0015 17.7 0.0 0.64 9.2 0.0 2.4 2 0 0 2 2 2 1 NB-ARC domain AAA_30 PF13604.6 AIN97420.1 - 0.0017 18.1 0.1 0.87 9.3 0.0 3.2 3 1 0 3 3 2 1 AAA domain AAA_13 PF13166.6 AIN97420.1 - 0.0021 16.8 0.1 2.3 6.7 0.0 3.3 3 0 0 3 3 3 1 AAA domain PduV-EutP PF10662.9 AIN97420.1 - 0.0026 17.5 0.0 0.55 10.0 0.0 2.6 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation dNK PF01712.19 AIN97420.1 - 0.0087 15.9 0.0 0.51 10.2 0.0 2.4 2 0 0 2 2 2 1 Deoxynucleoside kinase Mg_chelatase PF01078.21 AIN97420.1 - 0.011 15.1 0.0 4.2 6.7 0.0 2.4 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI Roc PF08477.13 AIN97420.1 - 0.023 14.9 0.0 1.3 9.3 0.0 2.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase RuvB_N PF05496.12 AIN97420.1 - 0.025 14.3 0.1 0.29 10.9 0.0 2.2 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain cobW PF02492.19 AIN97420.1 - 0.026 14.1 0.2 2.5 7.7 0.0 2.5 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain IstB_IS21 PF01695.17 AIN97420.1 - 0.027 14.2 0.0 2.6 7.8 0.0 2.5 2 0 0 2 2 2 0 IstB-like ATP binding protein Zeta_toxin PF06414.12 AIN97420.1 - 0.032 13.5 0.0 0.62 9.3 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin AAA_27 PF13514.6 AIN97420.1 - 0.035 13.7 0.0 17 5.0 0.0 3.1 3 0 0 3 3 3 0 AAA domain SRP54 PF00448.22 AIN97420.1 - 0.038 13.6 0.2 0.78 9.3 0.0 2.4 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain NTPase_1 PF03266.15 AIN97420.1 - 0.042 13.8 0.1 1.2 9.0 0.0 2.5 2 0 0 2 2 2 0 NTPase ATPase_2 PF01637.18 AIN97420.1 - 0.05 13.5 0.0 6.3 6.6 0.0 2.6 3 0 0 3 3 2 0 ATPase domain predominantly from Archaea MeaB PF03308.16 AIN97420.1 - 0.089 11.8 0.6 1.8 7.5 0.0 2.5 3 0 0 3 3 3 0 Methylmalonyl Co-A mutase-associated GTPase MeaB KapB PF08810.10 AIN97420.1 - 0.098 12.8 1.0 0.24 11.6 0.0 2.0 2 0 0 2 2 2 0 Kinase associated protein B ATP-synt_ab PF00006.25 AIN97420.1 - 0.15 11.7 0.0 9.6 5.8 0.0 2.3 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain HSBP1 PF06825.12 AIN97420.1 - 0.48 10.3 0.1 0.48 10.3 0.1 2.0 2 0 0 2 2 1 0 Heat shock factor binding protein 1 Vps53_N PF04100.12 AIN97421.1 - 7.8e-65 219.3 12.2 1.1e-64 218.8 12.2 1.2 1 0 0 1 1 1 1 Vps53-like, N-terminal DUF1664 PF07889.12 AIN97421.1 - 0.061 13.4 0.5 0.25 11.4 0.5 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) SNARE PF05739.19 AIN97421.1 - 0.27 11.3 2.2 0.69 10.0 1.3 2.2 1 1 1 2 2 2 0 SNARE domain XhlA PF10779.9 AIN97421.1 - 0.37 11.0 3.4 0.59 10.4 0.3 2.8 1 1 2 3 3 3 0 Haemolysin XhlA Atg8 PF02991.16 AIN97422.1 - 1.5e-09 38.0 0.0 2e-09 37.6 0.0 1.2 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like APG5 PF04106.12 AIN97422.1 - 0.0044 16.6 0.0 0.0044 16.6 0.0 1.1 1 0 0 1 1 1 1 Autophagy protein Apg5 DUF1117 PF06547.12 AIN97423.1 - 0.42 11.2 1.9 9.5 6.8 0.5 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1117) CAP_GLY PF01302.25 AIN97424.1 - 1.1e-17 63.7 0.2 2e-17 63.0 0.2 1.3 1 0 0 1 1 1 1 CAP-Gly domain DUF1878 PF08963.10 AIN97424.1 - 0.1 13.1 5.7 0.16 12.5 0.9 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1878) PAS_7 PF12860.7 AIN97424.1 - 0.78 9.9 5.3 1.2 9.3 0.2 3.0 2 0 0 2 2 2 0 PAS fold Anti-adapt_IraP PF10796.9 AIN97425.1 - 0.15 12.6 0.2 6.4 7.4 0.0 2.6 2 0 0 2 2 2 0 Sigma-S stabilisation anti-adaptor protein Dynein_light PF01221.18 AIN97426.1 - 1.2e-26 92.8 0.8 1.4e-26 92.6 0.8 1.1 1 0 0 1 1 1 1 Dynein light chain type 1 FKBP_C PF00254.28 AIN97427.1 - 8.1e-10 38.9 0.0 1.2e-09 38.4 0.0 1.3 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase FYVE PF01363.21 AIN97428.1 - 3.7e-13 49.4 8.3 3.7e-13 49.4 8.3 2.4 2 1 0 2 2 2 1 FYVE zinc finger WD40 PF00400.32 AIN97429.1 - 1.4e-15 57.4 3.3 0.00018 22.2 0.4 7.3 8 0 0 8 8 8 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 AIN97429.1 - 0.012 15.9 0.0 26 5.2 0.0 3.6 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain RAB3GAP2_N PF14655.6 AIN97429.1 - 0.017 14.4 0.1 3.6 6.7 0.0 2.7 2 1 0 3 3 3 0 Rab3 GTPase-activating protein regulatory subunit N-terminus Nup160 PF11715.8 AIN97429.1 - 0.027 13.1 0.1 0.45 9.1 0.0 2.3 2 0 0 2 2 2 0 Nucleoporin Nup120/160 eIF2A PF08662.11 AIN97429.1 - 0.055 13.3 0.0 0.72 9.7 0.0 2.3 3 0 0 3 3 3 0 Eukaryotic translation initiation factor eIF2A PseudoU_synth_1 PF01416.20 AIN97430.1 - 5.4e-15 55.8 0.0 3.6e-13 49.9 0.0 2.6 2 0 0 2 2 2 2 tRNA pseudouridine synthase Mrpl_C PF18502.1 AIN97431.1 - 0.025 14.8 0.3 0.025 14.8 0.3 1.9 2 0 0 2 2 2 0 54S ribosomal protein L8 C-terminal domain Cir_N PF10197.9 AIN97431.1 - 0.028 14.6 3.5 0.028 14.6 3.5 4.0 3 2 0 3 3 3 0 N-terminal domain of CBF1 interacting co-repressor CIR tRNA_synthFbeta PF17759.1 AIN97432.1 - 7e-40 136.7 0.0 1.1e-39 136.2 0.0 1.2 1 0 0 1 1 1 1 Phenylalanyl tRNA synthetase beta chain CLM domain PhetRS_B1 PF18262.1 AIN97432.1 - 2.2e-30 104.7 0.2 9.1e-30 102.7 0.0 2.0 2 0 0 2 2 2 1 Phe-tRNA synthetase beta subunit B1 domain B5 PF03484.15 AIN97432.1 - 1.8e-20 73.0 0.1 4.2e-15 55.8 0.0 2.6 2 0 0 2 2 2 2 tRNA synthetase B5 domain B3_4 PF03483.17 AIN97432.1 - 4.3e-17 62.3 0.0 7.1e-17 61.6 0.0 1.3 1 0 0 1 1 1 1 B3/4 domain CENP-X PF09415.10 AIN97435.1 - 0.11 12.8 4.5 0.35 11.2 0.1 3.2 2 1 0 2 2 2 0 CENP-S associating Centromere protein X DAGK_cat PF00781.24 AIN97436.1 - 1.2e-10 41.1 0.0 3.8e-07 29.8 0.0 2.7 2 0 0 2 2 2 2 Diacylglycerol kinase catalytic domain Mto2_bdg PF12808.7 AIN97438.1 - 0.37 11.1 4.8 0.14 12.5 0.5 2.6 3 0 0 3 3 3 0 Micro-tubular organiser Mto1 C-term Mto2-binding region DUF5320 PF17253.2 AIN97438.1 - 0.53 11.4 6.1 14 6.8 0.1 4.1 3 0 0 3 3 3 0 Family of unknown function (DUF5320) DUF2205 PF10224.9 AIN97438.1 - 3 7.9 4.9 16 5.6 1.5 3.0 2 0 0 2 2 2 0 Short coiled-coil protein DUF1192 PF06698.11 AIN97438.1 - 9.3 6.4 11.1 45 4.2 0.1 4.6 4 0 0 4 4 4 0 Protein of unknown function (DUF1192) Mito_carr PF00153.27 AIN97439.1 - 2e-51 171.9 3.5 3e-17 62.3 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein PCI PF01399.27 AIN97440.1 - 4.9e-08 33.4 0.0 1.7e-07 31.7 0.0 1.9 2 0 0 2 2 2 1 PCI domain Ank_2 PF12796.7 AIN97441.1 - 1.9e-28 98.9 13.1 3.7e-07 30.6 0.1 9.9 8 1 1 9 9 9 5 Ankyrin repeats (3 copies) Ank PF00023.30 AIN97441.1 - 5.6e-16 58.2 17.1 0.00063 20.1 0.2 11.5 12 0 0 12 12 12 3 Ankyrin repeat Ank_4 PF13637.6 AIN97441.1 - 1.9e-14 53.8 5.0 0.14 12.8 0.1 10.2 9 0 0 9 9 9 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 AIN97441.1 - 6.8e-14 50.6 26.5 0.0031 17.9 0.1 14.4 16 0 0 16 16 16 4 Ankyrin repeat Ank_5 PF13857.6 AIN97441.1 - 1.4e-08 34.8 17.9 0.12 12.8 0.0 9.9 11 1 1 12 12 12 3 Ankyrin repeats (many copies) SPX PF03105.19 AIN97444.1 - 0.018 15.0 9.6 0.028 14.3 9.6 1.2 1 0 0 1 1 1 0 SPX domain E2F_CC-MB PF16421.5 AIN97444.1 - 0.1 13.0 0.0 0.1 13.0 0.0 2.5 2 0 0 2 2 2 0 E2F transcription factor CC-MB domain DDE_Tnp_4 PF13359.6 AIN97444.1 - 0.35 10.5 1.2 1.3 8.7 0.1 2.2 2 0 0 2 2 2 0 DDE superfamily endonuclease Merozoite_SPAM PF07133.11 AIN97444.1 - 0.98 9.4 23.4 0.052 13.5 16.5 2.0 2 0 0 2 2 2 0 Merozoite surface protein (SPAM) SCP-1 PF05483.12 AIN97445.1 - 0.36 8.8 0.5 0.59 8.1 0.5 1.2 1 0 0 1 1 1 0 Synaptonemal complex protein 1 (SCP-1) CHCH PF06747.13 AIN97447.1 - 1.4e-05 25.1 1.2 2.3e-05 24.4 1.2 1.4 1 0 0 1 1 1 1 CHCH domain Cmc1 PF08583.10 AIN97447.1 - 0.029 14.4 0.8 0.052 13.6 0.8 1.4 1 0 0 1 1 1 0 Cytochrome c oxidase biogenesis protein Cmc1 like NDUF_B7 PF05676.13 AIN97447.1 - 0.03 14.0 2.0 0.055 13.2 2.0 1.4 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) COX17 PF05051.13 AIN97447.1 - 0.053 13.9 1.9 0.87 10.0 0.4 2.3 1 1 1 2 2 2 0 Cytochrome C oxidase copper chaperone (COX17) Actin PF00022.19 AIN97448.1 - 1.3e-74 251.3 0.0 1.5e-74 251.1 0.0 1.0 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.13 AIN97448.1 - 0.11 11.3 0.0 8.6 5.1 0.0 2.3 2 0 0 2 2 2 0 MreB/Mbl protein Fcf1 PF04900.12 AIN97449.1 - 4.2e-31 107.3 2.5 7.4e-31 106.5 2.5 1.4 1 0 0 1 1 1 1 Fcf1 PIN_9 PF18477.1 AIN97449.1 - 6.5e-13 49.0 0.0 1.1e-12 48.2 0.0 1.4 1 0 0 1 1 1 1 PIN like domain Thioredoxin PF00085.20 AIN97450.1 - 0.012 15.6 0.1 0.047 13.7 0.1 1.9 1 1 0 1 1 1 0 Thioredoxin Tape_meas_lam_C PF09718.10 AIN97452.1 - 1.9 8.6 5.3 1.7 8.8 0.0 3.0 3 0 0 3 3 3 0 Lambda phage tail tape-measure protein (Tape_meas_lam_C) Pex2_Pex12 PF04757.14 AIN97453.1 - 1.3e-35 123.0 0.2 3.2e-35 121.8 0.2 1.6 1 1 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4_3 PF13920.6 AIN97453.1 - 0.0088 15.9 4.6 0.019 14.8 4.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 AIN97453.1 - 0.017 15.4 1.9 0.032 14.6 1.9 1.4 1 0 0 1 1 1 0 Ring finger domain zf-C3HC4_2 PF13923.6 AIN97453.1 - 0.13 12.2 1.7 0.27 11.1 1.7 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) NMD3 PF04981.13 AIN97454.1 - 0.081 12.4 0.4 0.12 11.8 0.4 1.2 1 0 0 1 1 1 0 NMD3 family zf-Mss51 PF13824.6 AIN97454.1 - 0.12 12.5 0.1 0.23 11.6 0.1 1.6 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 zf_C2H2_13 PF18508.1 AIN97454.1 - 1 9.0 3.8 14 5.4 0.1 2.2 1 1 1 2 2 2 0 Zinc finger domain Surp PF01805.20 AIN97455.1 - 2.2e-13 50.0 0.6 2.2e-13 50.0 0.6 2.0 3 0 0 3 3 3 1 Surp module Band_7 PF01145.25 AIN97456.1 - 1.2e-28 100.4 0.1 2.7e-28 99.2 0.0 1.6 2 0 0 2 2 2 1 SPFH domain / Band 7 family Band_7_1 PF13421.6 AIN97456.1 - 0.0057 16.4 0.1 0.016 14.9 0.1 1.8 1 1 0 1 1 1 1 SPFH domain-Band 7 family Band_7 PF01145.25 AIN97457.1 - 4.9e-23 82.1 0.0 6.9e-23 81.6 0.0 1.2 1 0 0 1 1 1 1 SPFH domain / Band 7 family SH3_4 PF06347.13 AIN97458.1 - 0.07 13.0 0.1 0.28 11.1 0.0 2.0 2 0 0 2 2 2 0 Bacterial SH3 domain MBOAT PF03062.19 AIN97462.1 - 1e-17 64.5 9.5 1e-17 64.5 9.5 1.7 2 0 0 2 2 2 1 MBOAT, membrane-bound O-acyltransferase family BPD_transp_2 PF02653.16 AIN97462.1 - 0.0044 16.2 4.2 0.0078 15.4 4.2 1.3 1 1 0 1 1 1 1 Branched-chain amino acid transport system / permease component PAP2 PF01569.21 AIN97463.1 - 3.7e-25 88.3 3.6 3.7e-25 88.3 3.6 2.1 2 0 0 2 2 2 1 PAP2 superfamily PAP2_3 PF14378.6 AIN97463.1 - 6.4 6.4 13.6 0.022 14.5 2.3 2.5 3 1 0 3 3 3 0 PAP2 superfamily DUF2417 PF10329.9 AIN97464.1 - 0.0052 16.2 0.2 0.0052 16.2 0.2 1.8 1 1 1 2 2 2 1 Region of unknown function (DUF2417) DUF2207 PF09972.9 AIN97464.1 - 0.012 14.4 0.4 0.014 14.2 0.4 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF898 PF05987.13 AIN97464.1 - 0.025 13.7 0.7 0.027 13.5 0.7 1.0 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF898) DUF3671 PF12420.8 AIN97464.1 - 0.048 13.7 0.2 0.06 13.4 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function DUF3566 PF12089.8 AIN97464.1 - 0.049 14.0 1.4 0.065 13.6 1.4 1.1 1 0 0 1 1 1 0 Transmembrane domain of unknown function (DUF3566) Sar8_2 PF03058.14 AIN97464.1 - 0.059 13.9 1.2 0.086 13.4 1.2 1.4 1 1 0 1 1 1 0 Sar8.2 family Sigma_reg_N PF13800.6 AIN97464.1 - 0.07 13.4 0.6 0.31 11.4 0.2 1.9 2 0 0 2 2 2 0 Sigma factor regulator N-terminal TMEM154 PF15102.6 AIN97464.1 - 0.088 12.7 2.3 0.16 11.9 0.1 1.9 1 1 1 2 2 2 0 TMEM154 protein family Sec20 PF03908.13 AIN97464.1 - 1 9.3 2.5 36 4.4 1.3 2.2 2 0 0 2 2 2 0 Sec20 Orf78 PF06024.12 AIN97464.1 - 2.8 8.3 4.6 1.2 9.4 0.2 1.9 1 1 1 2 2 2 0 Orf78 (ac78) DUF1067 PF06362.11 AIN97465.1 - 0.15 12.9 0.2 0.53 11.1 0.1 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1067) PDZ_6 PF17820.1 AIN97466.1 - 6.4e-06 25.9 0.0 1.5e-05 24.8 0.0 1.6 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 AIN97466.1 - 0.00054 20.2 0.0 0.0041 17.4 0.0 2.4 2 1 1 3 3 3 1 PDZ domain DUF641 PF04859.12 AIN97466.1 - 0.0028 18.0 0.0 0.0085 16.4 0.0 1.8 1 0 0 1 1 1 1 Plant protein of unknown function (DUF641) PDZ PF00595.24 AIN97466.1 - 0.0036 17.6 0.0 0.008 16.5 0.0 1.5 1 0 0 1 1 1 1 PDZ domain Cation_efflux PF01545.21 AIN97467.1 - 4.4e-33 114.7 7.5 1.7e-19 70.4 2.5 2.2 2 0 0 2 2 2 2 Cation efflux family TBP PF00352.21 AIN97468.1 - 8.1e-42 141.1 0.1 1.1e-23 83.0 0.0 2.2 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) TPR_11 PF13414.6 AIN97469.1 - 6.1e-10 38.6 0.1 0.01 15.5 0.1 4.4 4 0 0 4 4 4 2 TPR repeat TPR_2 PF07719.17 AIN97469.1 - 9.4e-09 34.7 7.8 0.00034 20.5 0.0 5.3 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_17 PF13431.6 AIN97469.1 - 1.6e-07 31.2 0.6 0.024 15.0 0.0 3.7 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.28 AIN97469.1 - 4.5e-07 29.4 4.9 0.0016 18.2 0.0 4.2 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_8 PF13181.6 AIN97469.1 - 5.7e-07 29.3 2.9 0.0077 16.4 0.0 5.1 6 0 0 6 6 5 1 Tetratricopeptide repeat TPR_14 PF13428.6 AIN97469.1 - 0.00021 21.9 0.1 0.64 11.0 0.0 4.2 4 1 0 4 4 4 1 Tetratricopeptide repeat TPR_12 PF13424.6 AIN97469.1 - 0.00029 21.1 0.5 0.016 15.5 0.4 3.1 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_10 PF13374.6 AIN97469.1 - 0.013 15.4 0.0 0.14 12.1 0.1 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_16 PF13432.6 AIN97469.1 - 0.016 15.8 0.0 0.76 10.5 0.0 3.1 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_21 PF09976.9 AIN97469.1 - 0.029 14.1 0.1 0.045 13.5 0.1 1.3 1 0 0 1 1 1 0 Tetratricopeptide repeat-like domain TPR_6 PF13174.6 AIN97469.1 - 0.042 14.5 2.3 8.3 7.3 0.0 3.0 3 0 0 3 3 2 0 Tetratricopeptide repeat Sel1 PF08238.12 AIN97469.1 - 0.14 12.9 1.0 41 5.0 0.0 3.3 3 0 0 3 3 3 0 Sel1 repeat TPR_7 PF13176.6 AIN97469.1 - 0.17 12.0 1.5 0.4 10.8 0.4 2.4 2 1 0 2 2 2 0 Tetratricopeptide repeat PAP_assoc PF03828.19 AIN97470.1 - 2.2e-11 43.8 0.0 9.6e-11 41.7 0.1 2.1 2 0 0 2 2 2 1 Cid1 family poly A polymerase Peptidase_C1 PF00112.23 AIN97471.1 - 3.6e-68 229.9 5.9 5.8e-68 229.2 5.9 1.3 1 0 0 1 1 1 1 Papain family cysteine protease DUF3586 PF12131.8 AIN97471.1 - 1.9e-27 95.3 8.3 1.9e-27 95.3 8.3 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF3586) Inhibitor_I29 PF08246.12 AIN97471.1 - 4.8e-09 36.5 0.7 7.8e-09 35.8 0.7 1.4 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.15 AIN97471.1 - 0.0039 16.0 3.9 0.029 13.2 0.1 2.6 3 0 0 3 3 3 1 Peptidase C1-like family DUF4880 PF16220.5 AIN97471.1 - 0.071 13.0 0.4 12 5.8 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4880) SLR1-BP PF07333.12 AIN97471.1 - 0.17 12.3 1.5 0.64 10.5 1.5 2.0 1 0 0 1 1 1 0 S locus-related glycoprotein 1 binding pollen coat protein (SLR1-BP) RVT_1 PF00078.27 AIN97472.1 - 8.7e-07 28.7 0.1 1.6e-05 24.6 0.1 2.0 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) PIH1 PF08190.12 AIN97473.1 - 1.6e-08 34.2 0.0 2.9e-08 33.4 0.0 1.4 1 0 0 1 1 1 1 PIH1 N-terminal domain PIH1_CS PF18201.1 AIN97473.1 - 0.0031 17.9 0.0 0.0084 16.5 0.0 1.7 2 0 0 2 2 2 1 PIH1 CS-like domain Pkinase PF00069.25 AIN97474.1 - 1.1e-66 224.9 0.0 1.3e-66 224.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 AIN97474.1 - 6.4e-34 117.4 0.0 9.1e-34 116.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 AIN97474.1 - 2.6e-06 27.0 0.0 3.7e-06 26.5 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 AIN97474.1 - 0.0013 18.7 0.1 0.0024 17.8 0.1 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 AIN97474.1 - 0.02 14.3 0.5 0.038 13.4 0.5 1.5 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 AIN97474.1 - 0.086 11.8 0.0 0.19 10.6 0.0 1.3 1 1 0 1 1 1 0 Haspin like kinase domain Oxidored-like PF09791.9 AIN97475.1 - 1.4e-11 43.9 1.4 3.6e-11 42.6 1.4 1.7 1 0 0 1 1 1 1 Oxidoreductase-like protein, N-terminal NAD_binding_1 PF00175.21 AIN97475.1 - 2.8e-11 44.0 0.0 4.7e-11 43.3 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_1 PF00667.20 AIN97475.1 - 0.00014 21.5 0.0 0.0086 15.7 0.0 2.4 2 0 0 2 2 2 1 FAD binding domain NAD_binding_6 PF08030.12 AIN97475.1 - 0.14 12.2 0.1 23 5.1 0.0 2.3 2 0 0 2 2 2 0 Ferric reductase NAD binding domain DUF5522 PF17653.1 AIN97475.1 - 0.22 11.5 3.4 0.56 10.2 3.4 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5522) COX6B PF02297.17 AIN97476.1 - 0.1 12.8 1.8 0.17 12.1 1.8 1.5 1 1 0 1 1 1 0 Cytochrome oxidase c subunit VIb Pkinase PF00069.25 AIN97477.1 - 3.1e-43 148.0 0.0 1.4e-29 103.3 0.0 3.2 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 AIN97477.1 - 3.1e-18 66.0 0.0 9.7e-15 54.5 0.0 2.4 2 0 0 2 2 2 2 Protein tyrosine kinase zf-UDP PF14569.6 AIN97477.1 - 0.00093 19.3 5.4 0.0048 17.0 5.4 2.1 1 1 0 1 1 1 1 Zinc-binding RING-finger Pkinase_fungal PF17667.1 AIN97477.1 - 0.11 11.3 0.0 0.17 10.6 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase IF4E PF01652.18 AIN97478.1 - 1.6e-39 135.2 0.0 2.2e-39 134.8 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E TPT PF03151.16 AIN97480.1 - 3.8e-20 72.4 18.5 4.4e-20 72.2 18.5 1.0 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 AIN97480.1 - 0.0005 20.3 11.6 0.0005 20.3 11.6 2.5 1 1 0 2 2 2 1 EamA-like transporter family FKBP_C PF00254.28 AIN97482.1 - 6.5e-32 109.7 0.0 5.2e-31 106.8 0.0 2.4 2 0 0 2 2 2 1 FKBP-type peptidyl-prolyl cis-trans isomerase TPR_1 PF00515.28 AIN97482.1 - 1.5e-07 31.0 0.0 0.022 14.6 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 AIN97482.1 - 3.4e-07 30.7 0.4 2.3e-06 28.0 0.0 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.17 AIN97482.1 - 6.3e-07 29.0 0.1 0.016 15.3 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 AIN97482.1 - 1.6e-05 24.9 0.0 4.7e-05 23.4 0.0 1.8 1 0 0 1 1 1 1 Fis1 C-terminal tetratricopeptide repeat TPR_12 PF13424.6 AIN97482.1 - 0.00011 22.4 0.2 0.035 14.4 0.0 3.1 1 1 1 2 2 2 1 Tetratricopeptide repeat ANAPC3 PF12895.7 AIN97482.1 - 0.0034 17.6 0.0 0.01 16.1 0.0 1.7 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.6 AIN97482.1 - 0.0069 17.1 0.4 0.62 11.0 0.0 3.2 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.6 AIN97482.1 - 0.0069 16.3 0.1 0.62 10.2 0.0 2.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.6 AIN97482.1 - 0.0082 16.3 0.0 15 6.1 0.0 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_17 PF13431.6 AIN97482.1 - 0.049 14.0 0.2 21 5.8 0.0 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_10 PF13374.6 AIN97482.1 - 0.077 12.9 0.3 8 6.5 0.0 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat Carn_acyltransf PF00755.20 AIN97483.1 - 1.8e-143 479.3 0.0 2.4e-143 478.9 0.0 1.1 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase WD40 PF00400.32 AIN97484.1 - 8.5e-10 39.1 3.8 0.00091 20.0 0.0 4.8 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 AIN97484.1 - 1.7e-07 31.5 0.0 0.00017 21.8 0.0 3.5 3 0 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain IMPDH PF00478.25 AIN97485.1 - 9.5e-123 409.6 5.2 1.1e-122 409.3 5.2 1.0 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain CBS PF00571.28 AIN97485.1 - 2.8e-12 46.9 0.6 1.9e-05 25.0 0.0 2.6 2 0 0 2 2 2 2 CBS domain FMN_dh PF01070.18 AIN97485.1 - 8.2e-11 41.5 0.2 8.2e-11 41.5 0.2 1.6 2 0 0 2 2 2 1 FMN-dependent dehydrogenase NMO PF03060.15 AIN97485.1 - 7.8e-05 22.2 3.7 0.11 11.9 2.8 2.4 2 1 0 2 2 2 2 Nitronate monooxygenase His_biosynth PF00977.21 AIN97485.1 - 0.044 13.2 1.0 0.85 9.0 0.0 2.5 2 1 1 3 3 3 0 Histidine biosynthesis protein ELMO_CED12 PF04727.13 AIN97486.1 - 9.2e-28 97.5 0.0 1.4e-27 96.9 0.0 1.3 1 0 0 1 1 1 1 ELMO/CED-12 family Peptidase_M41 PF01434.18 AIN97488.1 - 1.1e-42 146.0 0.2 1.8e-42 145.3 0.2 1.4 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.29 AIN97488.1 - 6.5e-41 139.8 0.1 1.5e-39 135.4 0.0 2.4 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 AIN97488.1 - 6.4e-05 22.7 0.1 0.00038 20.2 0.1 2.4 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 AIN97488.1 - 0.00033 20.7 0.0 0.001 19.0 0.0 1.9 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 AIN97488.1 - 0.0025 18.2 6.9 0.051 14.0 0.6 3.7 2 1 0 2 2 2 1 AAA ATPase domain RuvB_N PF05496.12 AIN97488.1 - 0.0039 16.9 0.0 0.022 14.5 0.0 2.2 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 AIN97488.1 - 0.0059 16.9 2.8 0.055 13.7 0.1 3.0 2 1 1 3 3 3 1 AAA domain AAA_14 PF13173.6 AIN97488.1 - 0.017 15.1 0.0 0.036 14.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 AIN97488.1 - 0.03 14.9 0.3 0.085 13.4 0.0 2.0 2 1 0 2 2 1 0 AAA domain Peptidase_M50B PF13398.6 AIN97488.1 - 0.03 14.0 0.0 0.064 12.9 0.0 1.5 1 0 0 1 1 1 0 Peptidase M50B-like DUF2075 PF09848.9 AIN97488.1 - 0.042 13.1 0.0 0.072 12.3 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_3 PF07726.11 AIN97488.1 - 0.061 13.2 0.0 1.2 9.0 0.0 2.4 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.6 AIN97488.1 - 0.063 13.7 0.4 0.23 11.9 0.0 2.2 2 0 0 2 2 2 0 AAA domain TIP49 PF06068.13 AIN97488.1 - 0.071 12.3 0.0 0.14 11.3 0.0 1.6 1 0 0 1 1 1 0 TIP49 P-loop domain IstB_IS21 PF01695.17 AIN97488.1 - 0.079 12.7 0.1 0.18 11.5 0.1 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein LPP PF04728.13 AIN97488.1 - 0.12 12.8 0.2 0.63 10.5 0.0 2.4 2 0 0 2 2 2 0 Lipoprotein leucine-zipper AAA_2 PF07724.14 AIN97488.1 - 0.13 12.4 0.2 1 9.5 0.2 2.4 1 1 0 1 1 1 0 AAA domain (Cdc48 subfamily) SRP19 PF01922.17 AIN97489.1 - 2.5e-22 79.6 0.1 4.3e-22 78.9 0.0 1.4 1 1 0 1 1 1 1 SRP19 protein Pkinase PF00069.25 AIN97490.1 - 4.5e-21 75.4 0.0 5.2e-21 75.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 AIN97490.1 - 5.6e-07 29.1 0.0 1.4e-06 27.8 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 AIN97490.1 - 0.0022 16.8 0.0 0.0028 16.5 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase BTB_2 PF02214.22 AIN97491.1 - 1.5e-14 54.1 0.0 3.6e-14 52.9 0.0 1.6 1 0 0 1 1 1 1 BTB/POZ domain Atg8 PF02991.16 AIN97492.1 - 1.6e-38 131.1 0.0 1.8e-38 130.9 0.0 1.0 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like APG12 PF04110.13 AIN97492.1 - 9.8e-08 32.3 0.0 1.2e-07 32.0 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 START PF01852.19 AIN97493.1 - 0.00041 19.8 0.1 0.00056 19.4 0.1 1.3 1 0 0 1 1 1 1 START domain PseudoU_synth_1 PF01416.20 AIN97494.1 - 1.9e-10 41.1 0.1 3.4e-07 30.7 0.1 3.3 2 1 0 2 2 2 2 tRNA pseudouridine synthase WD40 PF00400.32 AIN97495.1 - 2.5e-16 59.7 4.8 0.0051 17.6 0.0 7.6 7 1 0 7 7 7 4 WD domain, G-beta repeat Nup160 PF11715.8 AIN97495.1 - 0.001 17.8 0.0 0.11 11.1 0.0 2.7 3 0 0 3 3 3 2 Nucleoporin Nup120/160 ANAPC4_WD40 PF12894.7 AIN97495.1 - 0.0068 16.7 0.0 7.4 6.9 0.0 4.0 4 0 0 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain DUF4407 PF14362.6 AIN97495.1 - 2.5 7.4 6.5 4.4 6.6 6.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Mon1 PF03164.14 AIN97496.1 - 2.2e-31 109.3 0.0 3e-16 59.5 0.0 3.0 2 1 0 2 2 2 2 Trafficking protein Mon1 Peptidase_C2 PF00648.21 AIN97497.1 - 1.2e-06 27.8 0.0 2.3e-06 26.9 0.0 1.4 1 0 0 1 1 1 1 Calpain family cysteine protease Pyr_redox_2 PF07992.14 AIN97498.1 - 1.1e-08 34.7 0.0 1.8e-06 27.4 0.0 2.5 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 AIN97498.1 - 7.7e-05 22.8 0.1 0.00024 21.2 0.1 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 AIN97498.1 - 0.00059 19.5 1.4 0.011 15.4 0.4 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.17 AIN97498.1 - 0.0052 16.1 0.0 0.0087 15.3 0.0 1.3 1 0 0 1 1 1 1 Thi4 family Trp_halogenase PF04820.14 AIN97498.1 - 0.0079 15.1 0.2 0.013 14.4 0.2 1.3 1 0 0 1 1 1 1 Tryptophan halogenase Lycopene_cycl PF05834.12 AIN97498.1 - 0.0089 15.1 0.3 0.0089 15.1 0.3 1.8 2 0 0 2 2 2 1 Lycopene cyclase protein ThiF PF00899.21 AIN97498.1 - 0.035 13.4 0.0 0.062 12.6 0.0 1.3 1 0 0 1 1 1 0 ThiF family NAD_binding_9 PF13454.6 AIN97498.1 - 0.056 13.4 2.2 0.16 11.9 0.1 2.7 3 0 0 3 3 2 0 FAD-NAD(P)-binding LapA_dom PF06305.11 AIN97498.1 - 0.066 13.0 1.6 0.26 11.1 0.7 2.3 3 0 0 3 3 3 0 Lipopolysaccharide assembly protein A domain TrkA_N PF02254.18 AIN97498.1 - 0.074 13.3 0.1 0.16 12.2 0.1 1.6 1 0 0 1 1 1 0 TrkA-N domain FAD_binding_3 PF01494.19 AIN97498.1 - 0.12 11.6 0.8 0.31 10.2 0.1 1.9 2 0 0 2 2 2 0 FAD binding domain Pyr_redox PF00070.27 AIN97498.1 - 0.13 12.9 0.0 0.68 10.5 0.1 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Sacchrp_dh_NADP PF03435.18 AIN97498.1 - 0.14 12.4 0.1 0.36 11.1 0.1 1.7 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain GRAS PF03514.14 AIN97498.1 - 0.16 10.9 0.0 0.31 9.9 0.0 1.4 1 0 0 1 1 1 0 GRAS domain family Mqo PF06039.15 AIN97498.1 - 0.16 10.5 0.0 0.24 9.9 0.0 1.2 1 0 0 1 1 1 0 Malate:quinone oxidoreductase (Mqo) HI0933_like PF03486.14 AIN97498.1 - 0.18 10.5 0.7 1.2 7.8 0.3 2.3 2 0 0 2 2 2 0 HI0933-like protein RIIa PF02197.17 AIN97499.1 - 2.3e-05 23.9 0.1 4.6e-05 23.0 0.1 1.6 1 0 0 1 1 1 1 Regulatory subunit of type II PKA R-subunit Dpy-30 PF05186.13 AIN97499.1 - 6.9e-05 22.5 0.0 0.00012 21.7 0.0 1.5 1 1 0 1 1 1 1 Dpy-30 motif Img2 PF05046.14 AIN97501.1 - 0.64 10.4 10.3 13 6.2 0.1 5.6 7 0 0 7 7 7 0 Mitochondrial large subunit ribosomal protein (Img2) Sas6_CC PF18594.1 AIN97501.1 - 4.8 7.0 7.0 40 4.1 0.4 4.5 4 0 0 4 4 4 0 Sas6/XLF/XRCC4 coiled-coil domain IFT81_CH PF18383.1 AIN97502.1 - 9e-32 109.9 0.6 4.3e-31 107.7 0.1 2.4 2 0 0 2 2 2 1 Intraflagellar transport 81 calponin homology domain Spc7 PF08317.11 AIN97502.1 - 0.00039 19.4 7.9 0.00039 19.4 7.9 4.1 1 1 2 4 4 4 3 Spc7 kinetochore protein Seryl_tRNA_N PF02403.22 AIN97502.1 - 0.0046 17.2 0.4 0.0046 17.2 0.4 6.2 2 1 3 7 7 7 1 Seryl-tRNA synthetase N-terminal domain Baculo_PEP_C PF04513.12 AIN97502.1 - 0.022 14.8 20.3 0.16 12.0 2.6 4.6 3 1 1 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus Cep57_MT_bd PF06657.13 AIN97502.1 - 0.048 14.1 0.1 0.048 14.1 0.1 5.3 6 2 2 8 8 8 0 Centrosome microtubule-binding domain of Cep57 DUF465 PF04325.13 AIN97502.1 - 0.078 13.0 1.9 0.23 11.5 0.1 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF465) IZUMO PF15005.6 AIN97502.1 - 0.21 12.1 16.3 0.8 10.2 0.2 4.5 3 2 0 4 4 4 0 Izumo sperm-egg fusion, Ig domain-associated ORF6C PF10552.9 AIN97502.1 - 4.5 7.4 7.9 0.29 11.2 0.4 3.0 3 1 0 3 3 3 0 ORF6C domain EMP24_GP25L PF01105.24 AIN97503.1 - 9.9e-12 45.2 0.2 3.5e-11 43.4 0.2 1.8 1 1 0 1 1 1 1 emp24/gp25L/p24 family/GOLD CRF1 PF10380.9 AIN97503.1 - 0.04 14.3 0.1 0.14 12.5 0.1 1.8 1 1 0 1 1 1 0 Transcription factor CRF1 CS PF04969.16 AIN97504.1 - 6.6e-07 30.3 0.0 1e-06 29.7 0.0 1.3 1 0 0 1 1 1 1 CS domain DUF1935 PF09149.10 AIN97505.1 - 1.1e-113 372.7 0.0 2.7e-29 101.6 0.0 4.1 4 0 0 4 4 4 4 Domain of unknown function (DUF1935) DUF1935 PF09149.10 AIN97506.1 - 8.9e-125 408.3 6.6 9.4e-33 112.7 0.1 4.1 4 0 0 4 4 4 4 Domain of unknown function (DUF1935) Glyco_hydro_26 PF02156.15 AIN97506.1 - 0.003 17.1 0.0 1 8.7 0.0 2.9 3 0 0 3 3 3 2 Glycosyl hydrolase family 26 OCRE PF17780.1 AIN97506.1 - 0.025 14.6 4.8 4.2 7.5 0.1 4.1 4 0 0 4 4 4 0 OCRE domain Methyltransf_25 PF13649.6 AIN97507.1 - 0.01 16.5 0.0 0.038 14.7 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase domain NICE-1 PF15845.5 AIN97507.1 - 0.37 11.6 3.5 1.5 9.6 2.2 2.7 2 0 0 2 2 2 0 Cysteine-rich C-terminal 1 family Nop25 PF09805.9 AIN97509.1 - 1.4e-11 45.0 3.1 1.4e-11 45.0 3.1 2.5 2 0 0 2 2 2 1 Nucleolar protein 12 (25kDa) Ldh_1_N PF00056.23 AIN97510.1 - 3.8e-43 146.9 0.0 5.1e-43 146.5 0.0 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.18 AIN97510.1 - 4.5e-41 140.6 0.0 6.3e-41 140.1 0.0 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain NAD_binding_10 PF13460.6 AIN97510.1 - 0.0027 17.6 0.0 0.0087 16.0 0.1 1.8 2 0 0 2 2 2 1 NAD(P)H-binding 3Beta_HSD PF01073.19 AIN97510.1 - 0.015 14.3 0.0 0.022 13.8 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Semialdhyde_dh PF01118.24 AIN97510.1 - 0.029 14.8 0.1 0.064 13.7 0.0 1.7 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain THF_DHG_CYH_C PF02882.19 AIN97510.1 - 0.047 13.0 0.1 0.51 9.6 0.1 2.1 1 1 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Glyco_hydro_3_C PF01915.22 AIN97510.1 - 0.11 12.5 0.2 0.5 10.3 0.1 1.8 1 1 0 2 2 2 0 Glycosyl hydrolase family 3 C-terminal domain Ldh_1_N PF00056.23 AIN97511.1 - 6.9e-37 126.7 0.0 9.5e-37 126.2 0.0 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.18 AIN97511.1 - 9.7e-37 126.5 0.0 1.6e-36 125.7 0.0 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain 3Beta_HSD PF01073.19 AIN97511.1 - 0.00038 19.6 0.0 0.00056 19.0 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Semialdhyde_dh PF01118.24 AIN97511.1 - 0.0055 17.1 0.0 0.01 16.3 0.0 1.5 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain THF_DHG_CYH_C PF02882.19 AIN97511.1 - 0.034 13.5 0.0 0.2 10.9 0.0 2.2 1 1 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain DapB_N PF01113.20 AIN97511.1 - 0.097 12.8 0.0 0.19 11.9 0.0 1.4 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Ldh_1_N PF00056.23 AIN97512.1 - 6e-46 156.0 0.2 8e-46 155.6 0.2 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.18 AIN97512.1 - 1.5e-44 151.8 0.0 2.6e-44 151.1 0.0 1.4 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain DapB_N PF01113.20 AIN97512.1 - 0.0015 18.6 0.0 0.0037 17.4 0.0 1.6 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus Semialdhyde_dh PF01118.24 AIN97512.1 - 0.0018 18.7 0.1 0.0055 17.1 0.0 1.9 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain 3Beta_HSD PF01073.19 AIN97512.1 - 0.0022 17.1 0.0 0.003 16.6 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Sacchrp_dh_NADP PF03435.18 AIN97512.1 - 0.0032 17.7 0.1 0.0067 16.7 0.1 1.5 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Ldh_1_C PF02866.18 AIN97513.1 - 1.5e-15 57.6 0.0 1.1e-14 54.7 0.0 2.0 1 1 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Ldh_1_N PF00056.23 AIN97513.1 - 6.6e-13 49.0 0.0 9.9e-13 48.4 0.0 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain THF_DHG_CYH_C PF02882.19 AIN97513.1 - 0.13 11.6 0.1 0.49 9.7 0.0 1.9 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain ADK PF00406.22 AIN97514.1 - 2.9e-24 85.9 0.0 3.7e-24 85.5 0.0 1.0 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 AIN97514.1 - 4.6e-13 49.8 0.0 1.3e-12 48.3 0.0 1.6 2 0 0 2 2 2 1 AAA domain ADK_lid PF05191.14 AIN97514.1 - 3.8e-11 42.8 0.0 8e-11 41.7 0.0 1.6 1 0 0 1 1 1 1 Adenylate kinase, active site lid Hydin_ADK PF17213.3 AIN97514.1 - 8.6e-07 29.4 0.0 0.0015 18.8 0.0 2.3 2 0 0 2 2 2 2 Hydin Adenylate kinase-like domain AAA_18 PF13238.6 AIN97514.1 - 1.7e-05 25.3 0.0 3.5e-05 24.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.6 AIN97514.1 - 0.0055 17.0 0.0 0.011 15.9 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 AIN97514.1 - 0.066 13.4 0.0 0.12 12.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain RuvB_N PF05496.12 AIN97514.1 - 0.087 12.6 0.0 0.26 11.0 0.0 1.7 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain AAA PF00004.29 AIN97514.1 - 0.18 12.2 0.2 0.75 10.2 0.0 2.1 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Phage_holin_3_7 PF05449.11 AIN97514.1 - 0.2 11.7 0.0 0.35 10.9 0.0 1.3 1 0 0 1 1 1 0 Putative 3TM holin, Phage_holin_3 ADK PF00406.22 AIN97515.1 - 1.3e-50 171.4 0.0 1.6e-50 171.1 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 AIN97515.1 - 1.1e-23 84.2 0.0 1.5e-23 83.7 0.0 1.2 1 0 0 1 1 1 1 AAA domain ADK_lid PF05191.14 AIN97515.1 - 3e-15 55.9 0.1 6.1e-15 54.9 0.1 1.5 1 0 0 1 1 1 1 Adenylate kinase, active site lid AAA_18 PF13238.6 AIN97515.1 - 0.00054 20.5 0.1 0.0019 18.7 0.0 1.9 2 1 0 2 2 2 1 AAA domain AAA_33 PF13671.6 AIN97515.1 - 0.0021 18.2 0.0 0.0057 16.8 0.0 1.7 1 1 0 1 1 1 1 AAA domain Hydin_ADK PF17213.3 AIN97515.1 - 0.011 16.0 0.0 0.068 13.4 0.0 2.0 1 1 1 2 2 2 0 Hydin Adenylate kinase-like domain AAA_28 PF13521.6 AIN97515.1 - 0.034 14.4 0.2 0.094 13.0 0.0 1.7 2 0 0 2 2 2 0 AAA domain NUDIX PF00293.28 AIN97516.1 - 0.079 13.0 0.1 0.19 11.8 0.1 1.6 1 0 0 1 1 1 0 NUDIX domain Herpes_UL52 PF03121.15 AIN97516.1 - 3.2 7.7 5.8 6.5 6.8 5.8 1.4 1 0 0 1 1 1 0 Herpesviridae UL52/UL70 DNA primase TraH PF06122.11 AIN97517.1 - 0.057 12.7 0.0 0.1 11.9 0.0 1.4 1 0 0 1 1 1 0 Conjugative relaxosome accessory transposon protein adh_short PF00106.25 AIN97518.1 - 1.1e-36 126.2 0.1 1.4e-36 125.8 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 AIN97518.1 - 2.4e-22 79.6 0.0 3.1e-22 79.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 AIN97518.1 - 9.2e-06 25.7 0.0 1.4e-05 25.1 0.0 1.2 1 0 0 1 1 1 1 KR domain Exog_C PF18026.1 AIN97518.1 - 0.0037 17.3 0.3 0.011 15.7 0.1 1.9 2 0 0 2 2 2 1 Endo/exonuclease (EXOG) C-terminal domain Sacchrp_dh_NADP PF03435.18 AIN97518.1 - 0.03 14.6 0.0 0.054 13.7 0.0 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Pkinase PF00069.25 AIN97520.1 - 9.5e-42 143.2 0.0 1.2e-41 142.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 AIN97520.1 - 2.6e-22 79.4 0.0 3.1e-22 79.1 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 AIN97520.1 - 1.8e-06 27.5 0.0 7e-06 25.6 0.0 1.8 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 AIN97520.1 - 0.038 13.9 0.0 0.091 12.7 0.0 1.5 1 1 1 2 2 2 0 Phosphotransferase enzyme family PIP49_C PF12260.8 AIN97520.1 - 0.1 12.2 0.0 0.15 11.6 0.0 1.3 1 0 0 1 1 1 0 Protein-kinase domain of FAM69 DnaJ PF00226.31 AIN97521.1 - 1.2e-12 47.7 0.0 3.5e-12 46.3 0.0 1.8 1 0 0 1 1 1 1 DnaJ domain CLPTM1 PF05602.12 AIN97522.1 - 7.1e-102 341.6 0.1 8.8e-102 341.3 0.1 1.1 1 0 0 1 1 1 1 Cleft lip and palate transmembrane protein 1 (CLPTM1) PQ-loop PF04193.14 AIN97522.1 - 0.055 13.2 1.5 0.13 12.0 0.3 2.1 2 0 0 2 2 2 0 PQ loop repeat Reticulon PF02453.17 AIN97523.1 - 0.35 10.8 3.1 0.6 10.0 0.6 2.3 2 0 0 2 2 2 0 Reticulon peroxidase PF00141.23 AIN97524.1 - 1.8e-48 165.2 0.0 2.9e-48 164.6 0.0 1.3 1 1 0 1 1 1 1 Peroxidase G6PD_C PF02781.16 AIN97525.1 - 7.9e-107 356.8 0.0 1e-106 356.4 0.0 1.1 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, C-terminal domain G6PD_N PF00479.22 AIN97525.1 - 1.2e-55 188.9 0.0 2.5e-55 187.8 0.0 1.5 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, NAD binding domain RIIa PF02197.17 AIN97525.1 - 0.00087 18.9 0.3 0.0037 16.9 0.1 2.0 2 0 0 2 2 2 1 Regulatory subunit of type II PKA R-subunit DS PF01916.17 AIN97526.1 - 7e-55 186.3 0.0 2.4e-36 125.5 0.0 4.1 4 0 0 4 4 4 4 Deoxyhypusine synthase AAA PF00004.29 AIN97527.1 - 1.1e-09 38.8 0.1 6.6e-07 29.8 0.0 2.5 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 AIN97527.1 - 4.3e-07 30.0 0.0 9.3e-07 28.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 AIN97527.1 - 0.00037 20.9 0.1 0.0019 18.6 0.0 2.0 1 1 0 2 2 2 1 AAA ATPase domain AAA_6 PF12774.7 AIN97527.1 - 0.0019 17.2 0.0 0.0031 16.5 0.0 1.3 1 0 0 1 1 1 1 Hydrolytic ATP binding site of dynein motor region RNA_helicase PF00910.22 AIN97527.1 - 0.0025 18.2 0.0 0.0075 16.7 0.0 1.8 1 0 0 1 1 1 1 RNA helicase AAA_33 PF13671.6 AIN97527.1 - 0.0045 17.2 0.0 0.014 15.6 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_2 PF07724.14 AIN97527.1 - 0.0054 16.9 0.0 0.011 15.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_28 PF13521.6 AIN97527.1 - 0.0073 16.6 0.4 0.032 14.5 0.0 2.1 2 0 0 2 2 2 1 AAA domain Viral_helicase1 PF01443.18 AIN97527.1 - 0.017 14.9 0.0 0.067 12.9 0.0 1.9 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase AAA_18 PF13238.6 AIN97527.1 - 0.037 14.6 0.0 0.089 13.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 AIN97527.1 - 0.041 13.4 0.0 0.081 12.4 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region DUF815 PF05673.13 AIN97527.1 - 0.06 12.5 0.0 0.1 11.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) TsaE PF02367.17 AIN97527.1 - 0.06 13.3 0.0 0.12 12.4 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_30 PF13604.6 AIN97527.1 - 0.061 13.0 0.5 0.25 11.1 0.0 2.2 3 0 0 3 3 3 0 AAA domain AAA_19 PF13245.6 AIN97527.1 - 0.065 13.6 0.0 0.13 12.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_3 PF07726.11 AIN97527.1 - 0.09 12.6 0.1 0.67 9.8 0.0 2.2 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) NACHT PF05729.12 AIN97527.1 - 0.1 12.5 0.0 0.28 11.1 0.0 1.7 1 0 0 1 1 1 0 NACHT domain AAA_22 PF13401.6 AIN97527.1 - 0.15 12.3 0.0 0.3 11.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain RuvB_N PF05496.12 AIN97527.1 - 0.16 11.7 0.0 0.35 10.6 0.0 1.5 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain eIF-5_eIF-2B PF01873.17 AIN97528.1 - 5.6e-33 113.3 0.0 1.1e-32 112.4 0.0 1.5 1 0 0 1 1 1 1 Domain found in IF2B/IF5 W2 PF02020.18 AIN97528.1 - 0.00075 19.6 0.3 0.0028 17.8 0.3 2.1 1 0 0 1 1 1 1 eIF4-gamma/eIF5/eIF2-epsilon FYDLN_acid PF09538.10 AIN97528.1 - 1.1 10.0 6.6 0.73 10.5 1.3 2.6 2 1 0 2 2 2 0 Protein of unknown function (FYDLN_acid) RNA_pol_Rpb1_5 PF04998.17 AIN97529.1 - 3.2e-78 262.9 0.0 4.5e-78 262.4 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.20 AIN97529.1 - 8.2e-67 224.6 0.0 1.4e-66 223.8 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_1 PF04997.12 AIN97529.1 - 1.4e-54 185.6 0.0 2e-54 185.0 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_3 PF04983.18 AIN97529.1 - 1.7e-31 109.3 0.0 3.5e-31 108.3 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.17 AIN97529.1 - 3.1e-31 107.5 0.0 7.7e-31 106.2 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 Fer4_17 PF13534.6 AIN97529.1 - 3.8 8.1 7.5 2.6 8.6 0.4 2.8 2 0 0 2 2 2 0 4Fe-4S dicluster domain Rpr2 PF04032.16 AIN97529.1 - 4 7.8 7.8 0.61 10.4 1.7 2.5 2 0 0 2 2 2 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain COG6 PF06419.11 AIN97530.1 - 4.5e-47 160.6 0.7 4.6e-44 150.7 0.0 2.8 3 0 0 3 3 3 2 Conserved oligomeric complex COG6 Occludin_ELL PF07303.13 AIN97530.1 - 0.0049 17.6 1.4 0.018 15.7 1.4 2.0 1 0 0 1 1 1 1 Occludin homology domain GCIP PF13324.6 AIN97530.1 - 0.028 14.0 0.1 0.096 12.3 0.1 1.9 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting PNP_UDP_1 PF01048.20 AIN97532.1 - 0.043 13.1 1.2 0.068 12.4 0.4 1.7 2 0 0 2 2 2 0 Phosphorylase superfamily DUF4785 PF16024.5 AIN97532.1 - 0.1 11.3 0.1 0.16 10.7 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4785) Ribosomal_S6 PF01250.17 AIN97533.1 - 0.0034 17.6 0.1 0.0052 17.0 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein S6 GAS PF13851.6 AIN97534.1 - 0.0025 17.2 5.4 0.0052 16.1 0.4 2.4 2 0 0 2 2 2 1 Growth-arrest specific micro-tubule binding Fib_alpha PF08702.10 AIN97534.1 - 0.005 17.0 1.7 0.18 12.0 0.0 2.9 2 1 0 2 2 2 1 Fibrinogen alpha/beta chain family EzrA PF06160.12 AIN97534.1 - 0.005 15.1 3.0 0.23 9.6 0.0 2.2 2 0 0 2 2 2 2 Septation ring formation regulator, EzrA Spc7 PF08317.11 AIN97534.1 - 0.12 11.2 6.6 1.1 8.1 1.3 2.6 2 1 0 2 2 2 0 Spc7 kinetochore protein AIP3 PF03915.13 AIN97534.1 - 0.18 10.8 3.3 0.076 12.1 0.7 1.6 2 0 0 2 2 2 0 Actin interacting protein 3 DUF4140 PF13600.6 AIN97534.1 - 1.9 9.0 11.9 3.3 8.2 0.6 3.1 2 1 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) Ribosomal_S25 PF03297.15 AIN97537.1 - 1.5e-36 124.7 5.5 1.7e-36 124.4 5.5 1.1 1 0 0 1 1 1 1 S25 ribosomal protein DUF3516 PF12029.8 AIN97537.1 - 0.12 11.4 1.3 0.14 11.2 1.3 1.2 1 1 0 1 1 1 0 Domain of unknown function (DUF3516) CarboxypepD_reg PF13620.6 AIN97539.1 - 5.2 7.4 7.2 7.5 6.9 0.4 4.0 3 1 0 3 3 3 0 Carboxypeptidase regulatory-like domain WD40 PF00400.32 AIN97540.1 - 5.8e-40 134.5 20.6 7.8e-07 29.7 0.2 7.8 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 AIN97540.1 - 1.1e-06 28.8 0.0 0.053 13.8 0.0 4.4 3 2 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Ion_trans PF00520.31 AIN97541.1 - 3.8e-116 386.5 115.5 5e-36 124.2 26.0 4.2 4 0 0 4 4 4 4 Ion transport protein GPHH PF16905.5 AIN97541.1 - 0.0059 16.3 0.0 0.019 14.7 0.0 1.9 1 0 0 1 1 1 1 Voltage-dependent L-type calcium channel, IQ-associated HEAT PF02985.22 AIN97542.1 - 1.2e-12 46.9 5.4 0.7 10.3 0.0 9.3 9 0 0 9 9 9 2 HEAT repeat HEAT_EZ PF13513.6 AIN97542.1 - 4.4e-11 43.0 6.3 9e-05 22.9 0.1 7.0 8 1 1 9 9 9 2 HEAT-like repeat Arm PF00514.23 AIN97542.1 - 2.2e-08 33.8 1.9 0.37 10.9 0.0 5.5 5 0 0 5 5 5 3 Armadillo/beta-catenin-like repeat IBN_N PF03810.19 AIN97542.1 - 3.6e-08 33.2 0.2 2.5e-07 30.5 0.0 2.7 2 0 0 2 2 2 1 Importin-beta N-terminal domain HEAT_2 PF13646.6 AIN97542.1 - 7.3e-08 32.7 9.6 0.009 16.4 0.1 6.6 6 2 1 7 7 6 2 HEAT repeats Vac14_Fab1_bd PF12755.7 AIN97542.1 - 2.8e-06 27.8 3.7 0.67 10.6 0.1 5.9 4 3 2 6 6 6 2 Vacuolar 14 Fab1-binding region DUF3385 PF11865.8 AIN97542.1 - 5.4e-06 26.4 2.1 0.02 14.8 0.1 4.9 4 1 0 5 5 5 2 Domain of unknown function (DUF3385) CLASP_N PF12348.8 AIN97542.1 - 0.0017 17.9 0.5 0.18 11.4 0.0 3.4 3 1 1 4 4 4 1 CLASP N terminal V-ATPase_H_C PF11698.8 AIN97542.1 - 0.0025 17.9 0.6 1.8 8.7 0.0 4.1 4 0 0 4 4 4 1 V-ATPase subunit H ApoLp-III PF07464.11 AIN97542.1 - 0.012 15.7 0.5 0.2 11.8 0.0 3.0 3 0 0 3 3 3 0 Apolipophorin-III precursor (apoLp-III) Telomere_reg-2 PF10193.9 AIN97542.1 - 0.077 13.4 4.8 2.9 8.4 0.0 4.5 3 2 2 5 5 5 0 Telomere length regulation protein Spidroin_N PF16763.5 AIN97542.1 - 1 9.4 6.2 5.3 7.1 0.0 3.5 3 0 0 3 3 3 0 Major ampullate spidroin 1, spider silk protein 1, N-term Glycos_transf_2 PF00535.26 AIN97543.1 - 0.0014 18.5 0.0 0.0025 17.6 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Trimer_CC PF08954.11 AIN97545.1 - 0.086 12.4 1.5 0.42 10.2 1.5 2.2 1 0 0 1 1 1 0 Trimerisation motif PDE6_gamma PF04868.12 AIN97546.1 - 2.6 8.3 4.6 2.9 8.2 0.6 2.9 3 0 0 3 3 3 0 Retinal cGMP phosphodiesterase, gamma subunit SNAP PF14938.6 AIN97547.1 - 2.3e-05 24.0 17.6 0.012 15.0 14.9 3.1 2 1 0 2 2 2 1 Soluble NSF attachment protein, SNAP TPR_2 PF07719.17 AIN97547.1 - 0.0009 19.2 4.6 0.09 12.9 1.2 4.2 2 1 2 4 4 4 1 Tetratricopeptide repeat TPR_12 PF13424.6 AIN97547.1 - 0.036 14.4 0.1 0.036 14.4 0.1 3.1 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_16 PF13432.6 AIN97547.1 - 0.037 14.7 8.3 0.68 10.6 0.9 4.5 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.28 AIN97547.1 - 0.062 13.1 1.5 6.7 6.7 0.0 3.3 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 AIN97547.1 - 0.62 11.0 5.6 5.6 8.1 0.3 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat LRR_4 PF12799.7 AIN97548.1 - 9.9e-10 38.5 13.5 0.055 13.9 0.4 6.2 3 1 4 7 7 7 6 Leucine Rich repeats (2 copies) GTP_EFTU PF00009.27 AIN97550.1 - 4.1e-43 147.2 0.2 6.5e-43 146.5 0.2 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain LepA_C PF06421.12 AIN97550.1 - 1.1e-30 106.0 1.5 1.8e-30 105.2 1.5 1.4 1 0 0 1 1 1 1 GTP-binding protein LepA C-terminus EFG_C PF00679.24 AIN97550.1 - 2.5e-14 53.1 0.2 7.9e-14 51.5 0.0 2.0 2 0 0 2 2 2 1 Elongation factor G C-terminus MMR_HSR1 PF01926.23 AIN97550.1 - 0.00013 22.0 0.0 0.00042 20.4 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase Ras PF00071.22 AIN97550.1 - 0.00045 19.9 0.1 0.0011 18.6 0.1 1.5 1 0 0 1 1 1 1 Ras family PduV-EutP PF10662.9 AIN97550.1 - 0.0035 17.1 0.0 0.03 14.1 0.0 2.2 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation Septin PF00735.18 AIN97550.1 - 0.015 14.6 0.1 0.3 10.3 0.0 2.3 2 0 0 2 2 2 0 Septin GTP_EFTU_D2 PF03144.25 AIN97550.1 - 0.029 14.8 0.0 0.068 13.6 0.0 1.7 1 0 0 1 1 1 0 Elongation factor Tu domain 2 DUF677 PF05055.12 AIN97551.1 - 0.00033 19.7 2.1 0.00038 19.4 2.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF677) DUF812 PF05667.11 AIN97551.1 - 0.0015 17.5 4.4 0.0015 17.5 4.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF812) Val_tRNA-synt_C PF10458.9 AIN97551.1 - 0.0023 18.2 5.2 0.54 10.6 2.4 3.4 3 0 0 3 3 3 1 Valyl tRNA synthetase tRNA binding arm MPS2 PF17060.5 AIN97551.1 - 0.0036 16.6 5.9 0.0041 16.4 5.9 1.0 1 0 0 1 1 1 1 Monopolar spindle protein 2 DUF2294 PF10057.9 AIN97551.1 - 0.011 15.8 1.2 0.015 15.4 0.7 1.5 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2294) Metal_resist PF13801.6 AIN97551.1 - 0.022 15.0 1.3 0.038 14.2 0.6 1.6 2 0 0 2 2 2 0 Heavy-metal resistance UPF0242 PF06785.11 AIN97551.1 - 0.028 14.5 5.5 0.03 14.4 5.5 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DUF641 PF04859.12 AIN97551.1 - 0.058 13.7 5.4 0.07 13.5 5.4 1.2 1 0 0 1 1 1 0 Plant protein of unknown function (DUF641) Ax_dynein_light PF10211.9 AIN97551.1 - 0.064 13.2 8.3 0.079 12.9 8.3 1.2 1 0 0 1 1 1 0 Axonemal dynein light chain Prefoldin_2 PF01920.20 AIN97551.1 - 0.078 12.9 9.3 0.085 12.8 8.4 1.6 1 1 0 1 1 1 0 Prefoldin subunit SlyX PF04102.12 AIN97551.1 - 0.086 13.5 6.0 0.25 12.0 1.9 2.3 1 1 1 2 2 2 0 SlyX Atg14 PF10186.9 AIN97551.1 - 0.091 11.8 5.7 0.095 11.8 5.7 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Tho2 PF11262.8 AIN97551.1 - 0.1 11.8 5.7 0.13 11.4 5.7 1.1 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 Troponin PF00992.20 AIN97551.1 - 0.1 12.9 14.3 0.15 12.3 14.3 1.4 1 1 0 1 1 1 0 Troponin MmgE_PrpD PF03972.14 AIN97551.1 - 0.13 10.8 1.6 0.17 10.4 1.6 1.1 1 0 0 1 1 1 0 MmgE/PrpD family DUF4446 PF14584.6 AIN97551.1 - 0.13 12.2 7.2 0.13 12.3 5.3 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF4446) DUF2533 PF10752.9 AIN97551.1 - 0.14 12.6 5.4 4.1 7.9 3.6 2.4 1 1 0 2 2 2 0 Protein of unknown function (DUF2533) Phage_GP20 PF06810.11 AIN97551.1 - 0.16 11.8 11.4 0.046 13.5 7.5 1.9 1 1 1 2 2 2 0 Phage minor structural protein GP20 Synaptobrevin PF00957.21 AIN97551.1 - 0.22 11.4 4.3 0.32 10.8 4.3 1.3 1 0 0 1 1 1 0 Synaptobrevin H-kinase_dim PF02895.14 AIN97551.1 - 0.38 11.2 3.1 0.29 11.6 1.8 1.5 2 0 0 2 2 1 0 Signal transducing histidine kinase, homodimeric domain Bestrophin PF01062.21 AIN97551.1 - 0.38 10.1 1.0 0.4 10.0 1.0 1.1 1 0 0 1 1 1 0 Bestrophin, RFP-TM, chloride channel DUF1664 PF07889.12 AIN97551.1 - 0.53 10.3 3.6 1 9.4 3.5 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) ZapB PF06005.12 AIN97551.1 - 0.62 10.5 13.5 0.6 10.6 12.6 1.6 1 1 0 1 1 1 0 Cell division protein ZapB EssA PF10661.9 AIN97551.1 - 0.67 9.8 10.9 0.91 9.4 10.3 1.6 1 1 0 1 1 1 0 WXG100 protein secretion system (Wss), protein EssA V_ATPase_I PF01496.19 AIN97551.1 - 0.91 7.4 5.8 1 7.2 5.8 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family APC_N_CC PF16689.5 AIN97551.1 - 1.5 8.9 8.2 7.9 6.6 1.2 2.2 1 1 1 2 2 2 0 Coiled-coil N-terminus of APC, dimerisation domain RRF PF01765.19 AIN97551.1 - 4.9 7.1 13.2 5.2 7.0 6.7 2.1 1 1 1 2 2 2 0 Ribosome recycling factor NMO PF03060.15 AIN97554.1 - 9.5e-51 173.1 1.8 7.2e-38 130.8 0.8 2.1 1 1 1 2 2 2 2 Nitronate monooxygenase FMN_dh PF01070.18 AIN97554.1 - 5.8e-10 38.7 0.2 9.7e-10 38.0 0.2 1.3 1 0 0 1 1 1 1 FMN-dependent dehydrogenase DHO_dh PF01180.21 AIN97554.1 - 5.8e-07 29.0 0.1 2e-06 27.3 0.1 1.7 2 0 0 2 2 2 1 Dihydroorotate dehydrogenase IMPDH PF00478.25 AIN97554.1 - 4.4e-05 22.6 1.7 0.00022 20.4 1.7 2.0 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.17 AIN97554.1 - 0.00042 19.6 0.5 0.00072 18.8 0.5 1.4 1 0 0 1 1 1 1 Conserved region in glutamate synthase ThiG PF05690.14 AIN97554.1 - 0.0054 16.1 0.5 0.0091 15.3 0.5 1.3 1 0 0 1 1 1 1 Thiazole biosynthesis protein ThiG His_biosynth PF00977.21 AIN97554.1 - 0.049 13.1 0.1 0.081 12.4 0.1 1.3 1 0 0 1 1 1 0 Histidine biosynthesis protein NanE PF04131.14 AIN97554.1 - 0.11 11.7 0.1 0.17 11.0 0.1 1.3 1 0 0 1 1 1 0 Putative N-acetylmannosamine-6-phosphate epimerase Sec20 PF03908.13 AIN97556.1 - 0.021 14.7 1.4 0.065 13.2 1.4 1.8 1 0 0 1 1 1 0 Sec20 Pantoate_transf PF02548.15 AIN97557.1 - 0.22 10.8 2.8 0.3 10.4 0.8 2.0 2 0 0 2 2 2 0 Ketopantoate hydroxymethyltransferase PMEI PF04043.15 AIN97557.1 - 0.86 9.9 9.8 0.16 12.3 3.6 2.7 2 0 0 2 2 2 0 Plant invertase/pectin methylesterase inhibitor LRR_8 PF13855.6 AIN97558.1 - 0.003 17.3 0.2 0.12 12.2 0.0 3.0 2 0 0 2 2 2 1 Leucine rich repeat JAB PF01398.21 AIN97559.1 - 6.8e-28 97.0 0.0 1.4e-27 96.0 0.0 1.5 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Prok-JAB PF14464.6 AIN97559.1 - 1.6e-08 34.3 0.0 2.7e-08 33.6 0.0 1.4 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain MitMem_reg PF13012.6 AIN97559.1 - 0.00064 20.1 0.2 0.0015 19.0 0.2 1.6 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function ABC_tran PF00005.27 AIN97561.1 - 7.5e-39 133.4 0.0 2.8e-22 79.7 0.0 2.7 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 AIN97561.1 - 1.1e-34 120.4 21.4 1.1e-20 74.4 6.9 3.4 3 0 0 3 3 3 3 ABC transporter transmembrane region SMC_N PF02463.19 AIN97561.1 - 7.4e-08 32.1 0.6 0.0037 16.7 0.0 4.1 2 2 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 AIN97561.1 - 4.9e-06 26.6 0.1 2.2 8.0 0.0 4.2 4 0 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 AIN97561.1 - 9.3e-06 25.6 0.0 0.038 13.9 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 AIN97561.1 - 1.3e-05 25.2 0.1 0.016 15.2 0.1 2.5 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_29 PF13555.6 AIN97561.1 - 0.00029 20.5 0.0 0.4 10.4 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.6 AIN97561.1 - 0.00052 20.4 4.5 0.015 15.7 0.0 3.9 2 1 0 2 2 2 1 AAA ATPase domain AAA_25 PF13481.6 AIN97561.1 - 0.0022 17.6 0.4 0.13 11.8 0.0 3.2 4 0 0 4 4 4 1 AAA domain AAA_22 PF13401.6 AIN97561.1 - 0.01 16.1 0.0 0.39 11.0 0.0 2.9 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.6 AIN97561.1 - 0.011 16.3 0.1 3.1 8.2 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 AIN97561.1 - 0.015 15.7 0.0 2.9 8.3 0.0 3.2 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) AIG1 PF04548.16 AIN97561.1 - 0.017 14.5 0.1 1.3 8.3 0.2 2.4 2 0 0 2 2 2 0 AIG1 family Dynamin_N PF00350.23 AIN97561.1 - 0.023 14.8 0.1 1 9.4 0.2 2.5 2 0 0 2 2 2 0 Dynamin family RNA_helicase PF00910.22 AIN97561.1 - 0.066 13.6 0.1 4.6 7.7 0.0 3.0 3 0 0 3 3 3 0 RNA helicase ESM4 PF15952.5 AIN97561.1 - 0.27 11.7 1.2 0.66 10.4 0.0 2.2 3 0 0 3 3 2 0 Enhancer of split M4 family NUDE_C PF04880.13 AIN97562.1 - 0.0067 16.9 0.2 0.0067 16.9 0.2 2.8 3 0 0 3 3 3 1 NUDE protein, C-terminal conserved region CENP-F_leu_zip PF10473.9 AIN97562.1 - 0.041 13.9 35.1 0.079 13.0 1.6 4.6 3 1 1 4 4 4 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 HHH_2 PF12826.7 AIN97562.1 - 0.11 12.6 0.1 0.55 10.4 0.1 2.2 1 0 0 1 1 1 0 Helix-hairpin-helix motif COMM_domain PF07258.14 AIN97562.1 - 0.83 9.8 5.4 26 5.0 3.2 3.5 2 1 0 2 2 2 0 COMM domain Fez1 PF06818.15 AIN97562.1 - 0.91 9.9 27.8 0.25 11.8 0.2 3.8 3 1 1 4 4 4 0 Fez1 DUF948 PF06103.11 AIN97562.1 - 5.7 7.3 12.4 2.8 8.3 0.4 3.8 3 1 0 3 3 3 0 Bacterial protein of unknown function (DUF948) UPF0242 PF06785.11 AIN97563.1 - 0.0034 17.5 9.0 0.029 14.5 9.0 2.0 1 1 0 1 1 1 1 Uncharacterised protein family (UPF0242) N-terminus DUF4164 PF13747.6 AIN97563.1 - 0.14 12.4 8.0 1.6 9.1 0.6 2.7 1 1 2 3 3 3 0 Domain of unknown function (DUF4164) CENP-F_leu_zip PF10473.9 AIN97563.1 - 0.53 10.3 15.7 9.8 6.2 15.1 2.4 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 SHE3 PF17078.5 AIN97563.1 - 0.64 9.7 7.4 1.4 8.5 0.6 2.1 1 1 1 2 2 2 0 SWI5-dependent HO expression protein 3 DUF5082 PF16888.5 AIN97563.1 - 1.8 8.9 5.6 1.4 9.2 2.3 2.1 2 1 0 2 2 2 0 Domain of unknown function (DUF5082) TMF_TATA_bd PF12325.8 AIN97563.1 - 2.2 8.5 12.0 10 6.3 0.0 2.2 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding GAS PF13851.6 AIN97563.1 - 3.5 6.9 11.4 6.5 6.0 6.8 2.3 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding DUF3450 PF11932.8 AIN97563.1 - 3.8 6.7 7.6 8.5 5.6 4.7 2.2 1 1 0 2 2 2 0 Protein of unknown function (DUF3450) DUF1387 PF07139.11 AIN97563.1 - 4.1 7.1 8.9 1.3 8.7 5.1 1.8 1 1 0 2 2 2 0 Protein of unknown function (DUF1387) APG6_N PF17675.1 AIN97563.1 - 7 7.2 15.7 25 5.4 10.5 2.1 1 1 1 2 2 2 0 Apg6 coiled-coil region AAA_23 PF13476.6 AIN97564.1 - 0.0037 17.8 9.1 0.0037 17.8 9.1 2.5 2 1 0 2 2 2 1 AAA domain FTA4 PF13093.6 AIN97564.1 - 0.0055 16.6 0.1 0.0055 16.6 0.1 4.2 3 2 1 4 4 4 1 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 EspA PF03433.13 AIN97564.1 - 0.089 12.6 0.0 0.089 12.6 0.0 3.2 4 0 0 4 4 4 0 EspA-like secreted protein Nup88 PF10168.9 AIN97564.1 - 1.5 6.6 14.6 0.17 9.7 4.0 2.4 2 0 0 2 2 2 0 Nuclear pore component SpecificRecomb PF10136.9 AIN97564.1 - 1.5 7.0 14.6 1.6 7.0 7.7 2.9 3 1 1 4 4 4 0 Site-specific recombinase DUF2039 PF10217.9 AIN97565.1 - 1.8e-22 79.5 22.2 2.7e-22 78.9 22.2 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2039) Tankyrase_bdg_C PF15327.6 AIN97565.1 - 0.0035 17.8 0.6 0.0048 17.4 0.6 1.2 1 0 0 1 1 1 1 Tankyrase binding protein C terminal domain Cript PF10235.9 AIN97565.1 - 0.35 11.5 15.0 0.97 10.1 15.0 1.8 1 1 0 1 1 1 0 Microtubule-associated protein CRIPT Neuropeptide_S PF14993.6 AIN97566.1 - 0.0041 16.9 1.3 1.9 8.4 0.4 3.2 2 0 0 2 2 2 2 Neuropeptide S precursor protein Tcp10_C PF07202.13 AIN97567.1 - 0.0034 17.4 0.4 0.014 15.3 0.3 1.9 1 1 0 1 1 1 1 T-complex protein 10 C-terminus Sod_Fe_C PF02777.18 AIN97567.1 - 0.0069 16.5 0.0 0.018 15.2 0.0 1.7 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain Med3 PF11593.8 AIN97567.1 - 6 5.9 10.7 9.4 5.3 10.7 1.4 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal SpoIIE PF07228.12 AIN97568.1 - 4.8e-09 36.4 0.0 6e-09 36.1 0.0 1.1 1 0 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) PP2C_2 PF13672.6 AIN97568.1 - 0.013 15.1 0.0 0.029 14.0 0.0 1.4 1 1 0 1 1 1 0 Protein phosphatase 2C MMS1_N PF10433.9 AIN97568.1 - 0.033 12.8 0.0 0.036 12.7 0.0 1.0 1 0 0 1 1 1 0 Mono-functional DNA-alkylating methyl methanesulfonate N-term PP2C PF00481.21 AIN97568.1 - 0.067 12.8 0.0 0.13 11.9 0.0 1.4 1 0 0 1 1 1 0 Protein phosphatase 2C CBF PF03914.17 AIN97569.1 - 2.4e-27 96.0 0.3 3.9e-27 95.3 0.3 1.3 1 0 0 1 1 1 1 CBF/Mak21 family DUF4844 PF16133.5 AIN97570.1 - 0.00077 20.0 0.1 1.6 9.3 0.0 2.9 2 1 1 3 3 3 2 Domain of unknown function (DUF4844) NAD_binding_10 PF13460.6 AIN97571.1 - 2.4e-08 34.1 0.0 2.7e-05 24.1 0.1 2.3 2 0 0 2 2 2 2 NAD(P)H-binding NmrA PF05368.13 AIN97571.1 - 4.8e-05 23.0 0.4 0.00013 21.6 0.1 1.7 2 0 0 2 2 2 1 NmrA-like family Epimerase PF01370.21 AIN97571.1 - 0.016 14.7 0.1 0.096 12.1 0.0 2.1 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 AIN97571.1 - 0.037 13.2 0.2 0.059 12.5 0.2 1.2 1 0 0 1 1 1 0 Male sterility protein adh_short PF00106.25 AIN97571.1 - 0.11 11.9 0.1 0.17 11.3 0.1 1.3 1 0 0 1 1 1 0 short chain dehydrogenase Shikimate_DH PF01488.20 AIN97571.1 - 0.11 12.5 0.1 0.19 11.8 0.1 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase 3HCDH_N PF02737.18 AIN97571.1 - 0.16 11.9 0.0 0.22 11.4 0.0 1.2 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Metallophos PF00149.28 AIN97573.1 - 7.6e-32 111.5 0.1 1e-31 111.1 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 AIN97573.1 - 1.8e-14 53.9 0.8 2.9e-14 53.2 0.8 1.3 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain Metallophos PF00149.28 AIN97574.1 - 4.8e-31 108.9 0.1 6.8e-31 108.4 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 AIN97574.1 - 2.8e-14 53.3 0.7 4.7e-14 52.5 0.7 1.4 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain Metallophos PF00149.28 AIN97575.1 - 1.7e-31 110.3 0.1 2.3e-31 109.9 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 AIN97575.1 - 1.6e-14 54.1 1.9 2.5e-14 53.4 1.9 1.3 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain Pcc1 PF09341.10 AIN97576.1 - 2.5e-09 37.2 0.0 4.2e-09 36.4 0.0 1.4 1 0 0 1 1 1 1 Transcription factor Pcc1 EF1_GNE PF00736.19 AIN97577.1 - 3e-27 94.6 0.8 4.5e-27 94.1 0.8 1.3 1 0 0 1 1 1 1 EF-1 guanine nucleotide exchange domain GST_C_2 PF13410.6 AIN97578.1 - 0.053 13.5 0.0 0.09 12.8 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain EF1_GNE PF00736.19 AIN97579.1 - 9.1e-27 93.1 0.8 1.4e-26 92.4 0.8 1.3 1 0 0 1 1 1 1 EF-1 guanine nucleotide exchange domain GST_C_2 PF13410.6 AIN97579.1 - 0.013 15.5 0.0 0.032 14.2 0.0 1.7 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Metallophos PF00149.28 AIN97580.1 - 2.3e-32 113.2 0.0 2.8e-32 112.9 0.0 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 AIN97580.1 - 1.7e-05 25.2 0.0 3.1e-05 24.3 0.0 1.5 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain Ribosomal_L13 PF00572.18 AIN97581.1 - 1.4e-06 28.6 3.3 2.8e-05 24.4 0.9 2.7 2 1 0 2 2 2 1 Ribosomal protein L13 DUF4455 PF14643.6 AIN97581.1 - 0.051 12.2 1.2 0.074 11.7 1.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4455) Pox_Ag35 PF03286.14 AIN97582.1 - 0.2 11.4 7.1 0.38 10.5 7.1 1.3 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Prothymosin PF03247.14 AIN97582.1 - 0.88 10.1 22.5 2.2 8.8 22.5 1.6 1 0 0 1 1 1 0 Prothymosin/parathymosin family RNA_pol_Rpb6 PF01192.22 AIN97584.1 - 1.8e-14 53.3 1.8 2.2e-14 53.1 0.3 1.9 2 0 0 2 2 2 1 RNA polymerase Rpb6 DUF2169 PF09937.9 AIN97584.1 - 0.028 13.9 0.0 0.032 13.7 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2169) UQ_con PF00179.26 AIN97585.1 - 6.1e-15 55.1 0.0 9.1e-15 54.5 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Med3 PF11593.8 AIN97585.1 - 0.00056 19.2 7.3 0.00065 19.0 7.3 1.1 1 0 0 1 1 1 1 Mediator complex subunit 3 fungal DUF2046 PF09755.9 AIN97587.1 - 0.021 14.0 2.8 0.053 12.8 2.8 1.6 1 0 0 1 1 1 0 Uncharacterized conserved protein H4 (DUF2046) CLZ PF16526.5 AIN97587.1 - 0.19 12.1 2.0 9.7 6.6 0.1 2.5 2 0 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Med3 PF11593.8 AIN97587.1 - 0.81 8.8 3.2 2.4 7.3 3.2 1.8 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal PAP2 PF01569.21 AIN97587.1 - 1.5 8.5 4.8 0.99 9.2 1.2 2.3 2 0 0 2 2 2 0 PAP2 superfamily HIP1_clath_bdg PF16515.5 AIN97587.1 - 2.2 8.9 8.9 1.9 9.2 6.3 2.1 1 1 1 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 SR-25 PF10500.9 AIN97587.1 - 3.3 7.2 13.9 7.3 6.1 13.9 1.5 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Pkinase PF00069.25 AIN97589.1 - 7.6e-42 143.5 0.0 8.8e-31 107.2 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 AIN97589.1 - 2.6e-19 69.5 0.0 1e-13 51.2 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.23 AIN97589.1 - 0.072 13.0 0.0 0.17 11.8 0.0 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.14 AIN97589.1 - 0.22 10.8 0.0 0.37 10.1 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family INCA1 PF15142.6 AIN97589.1 - 1.9 8.5 5.9 0.99 9.4 0.4 3.0 4 0 0 4 4 4 0 INCA1 Amastin PF07344.11 AIN97590.1 - 7e-54 181.9 9.9 8.4e-54 181.6 9.9 1.0 1 0 0 1 1 1 1 Amastin surface glycoprotein DUF2157 PF09925.9 AIN97590.1 - 0.0074 16.1 2.3 0.42 10.4 0.0 2.2 1 1 1 2 2 2 2 Predicted membrane protein (DUF2157) DUF4293 PF14126.6 AIN97590.1 - 0.072 13.3 8.0 0.19 12.0 8.0 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4293) DUF4337 PF14235.6 AIN97590.1 - 0.31 11.1 1.2 0.65 10.1 1.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) DUF3087 PF11286.8 AIN97590.1 - 2.4 7.6 4.8 0.45 10.0 1.2 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3087) PelG PF16933.5 AIN97590.1 - 2.6 6.8 13.1 0.23 10.3 7.9 1.7 2 0 0 2 2 2 0 Putative exopolysaccharide Exporter (EPS-E) Amastin PF07344.11 AIN97591.1 - 4.8e-53 179.2 11.8 5.7e-53 178.9 11.8 1.1 1 0 0 1 1 1 1 Amastin surface glycoprotein PMP22_Claudin PF00822.20 AIN97591.1 - 2.1e-05 24.4 8.5 2.8e-05 24.1 8.5 1.2 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family DUF3087 PF11286.8 AIN97591.1 - 0.039 13.4 1.0 0.039 13.4 1.0 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3087) Pho86 PF11124.8 AIN97591.1 - 0.22 11.0 0.1 0.22 11.0 0.1 2.0 1 1 0 2 2 2 0 Inorganic phosphate transporter Pho86 SUR7 PF06687.12 AIN97591.1 - 2.2 7.8 26.6 0.089 12.4 8.4 3.0 1 1 1 3 3 3 0 SUR7/PalI family Amastin PF07344.11 AIN97592.1 - 6.8e-43 146.2 11.2 8.1e-43 145.9 11.2 1.0 1 0 0 1 1 1 1 Amastin surface glycoprotein Myosin_head PF00063.21 AIN97593.1 - 8.2e-211 701.8 0.0 8.3e-127 424.2 0.0 2.1 2 0 0 2 2 2 2 Myosin head (motor domain) Myosin_TH1 PF06017.13 AIN97593.1 - 7.4e-08 32.3 0.0 0.008 15.9 0.0 2.6 3 0 0 3 3 3 2 Unconventional myosin tail, actin- and lipid-binding FYVE PF01363.21 AIN97593.1 - 7.1e-05 22.9 8.9 0.00018 21.6 8.9 1.6 1 0 0 1 1 1 1 FYVE zinc finger AAA_16 PF13191.6 AIN97593.1 - 0.019 15.4 1.9 0.041 14.2 0.0 2.4 2 0 0 2 2 2 0 AAA ATPase domain AAA_11 PF13086.6 AIN97593.1 - 0.054 13.3 5.0 1.3 8.7 4.2 2.3 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 AIN97593.1 - 0.15 12.3 0.0 0.41 10.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain HTH_30 PF13556.6 AIN97594.1 - 0.035 13.9 0.3 0.14 12.0 0.3 2.0 1 0 0 1 1 1 0 PucR C-terminal helix-turn-helix domain FAD_SOX PF18371.1 AIN97594.1 - 0.06 13.7 0.1 0.15 12.5 0.1 1.6 1 0 0 1 1 1 0 Flavin adenine dinucleotide (FAD)-dependent sulfhydryl oxidase HALZ PF02183.18 AIN97594.1 - 0.2 11.9 0.6 0.38 11.0 0.6 1.4 1 0 0 1 1 1 0 Homeobox associated leucine zipper N2227 PF07942.12 AIN97595.1 - 1.1e-94 316.7 0.0 1.4e-94 316.3 0.0 1.1 1 0 0 1 1 1 1 N2227-like protein Methyltransf_23 PF13489.6 AIN97595.1 - 0.16 11.8 0.0 0.31 10.9 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain EF-hand_7 PF13499.6 AIN97596.1 - 6.1e-09 36.2 0.1 9.6e-09 35.6 0.1 1.3 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_8 PF13833.6 AIN97596.1 - 7e-09 35.4 0.2 1.4e-08 34.5 0.2 1.4 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.32 AIN97596.1 - 1.5e-06 27.3 0.1 0.0012 18.2 0.2 2.8 2 1 1 3 3 3 2 EF hand EF-hand_5 PF13202.6 AIN97596.1 - 0.00016 21.0 0.3 0.005 16.3 0.1 2.5 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.6 AIN97596.1 - 0.00023 20.8 0.1 0.07 13.1 0.1 2.7 1 1 0 2 2 2 1 EF-hand domain EF-hand_4 PF12763.7 AIN97596.1 - 0.069 13.1 0.0 0.36 10.8 0.0 1.9 2 0 0 2 2 2 0 Cytoskeletal-regulatory complex EF hand UPRTase PF14681.6 AIN97597.1 - 2.1e-70 236.4 0.0 2.5e-70 236.1 0.0 1.0 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.27 AIN97597.1 - 8.1e-06 25.4 0.0 1.5e-05 24.6 0.0 1.3 1 1 0 1 1 1 1 Phosphoribosyl transferase domain SET PF00856.28 AIN97598.1 - 1.4e-13 51.6 0.0 8.3e-13 49.1 0.0 2.2 2 1 0 2 2 2 1 SET domain TPR_2 PF07719.17 AIN97598.1 - 3e-09 36.3 7.3 0.00059 19.7 0.2 5.3 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_8 PF13181.6 AIN97598.1 - 0.00021 21.3 1.0 0.16 12.2 0.1 3.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.6 AIN97598.1 - 0.00039 20.7 6.6 0.12 12.6 0.3 4.2 3 2 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.28 AIN97598.1 - 0.0005 19.8 11.4 0.01 15.6 0.5 4.6 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.6 AIN97598.1 - 0.0024 18.6 6.5 0.084 13.7 0.0 4.8 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_7 PF13176.6 AIN97598.1 - 0.1 12.7 2.1 26 5.2 0.1 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_9 PF13371.6 AIN97598.1 - 0.24 11.6 1.3 1.4 9.1 0.2 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_10 PF13374.6 AIN97598.1 - 1.9 8.4 7.3 0.72 9.8 0.1 3.5 4 0 0 4 4 4 0 Tetratricopeptide repeat Peptidase_M41 PF01434.18 AIN97600.1 - 3.8e-40 137.8 0.0 6.5e-40 137.0 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.29 AIN97600.1 - 4.8e-39 133.8 0.0 8.6e-39 133.0 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 AIN97600.1 - 1.9e-10 40.4 0.0 4.8e-10 39.1 0.0 1.6 1 0 0 1 1 1 1 AAA+ lid domain AAA_2 PF07724.14 AIN97600.1 - 0.00034 20.8 0.0 0.00073 19.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) RuvB_N PF05496.12 AIN97600.1 - 0.00042 20.1 0.0 0.0012 18.6 0.0 1.8 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 AIN97600.1 - 0.00045 20.6 0.0 0.15 12.5 0.1 2.7 1 1 1 2 2 2 1 AAA ATPase domain TIP49 PF06068.13 AIN97600.1 - 0.0032 16.7 0.0 0.0052 16.0 0.0 1.3 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_5 PF07728.14 AIN97600.1 - 0.0035 17.4 1.6 0.2 11.7 0.2 3.9 3 1 0 3 3 3 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 AIN97600.1 - 0.01 16.1 0.0 0.31 11.3 0.0 2.6 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.6 AIN97600.1 - 0.014 14.9 0.1 4.5 6.8 0.0 2.6 1 1 1 2 2 2 0 AAA domain AAA_14 PF13173.6 AIN97600.1 - 0.034 14.2 0.0 0.064 13.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 AIN97600.1 - 0.053 13.2 0.0 0.1 12.3 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein Mg_chelatase PF01078.21 AIN97600.1 - 0.059 12.7 0.1 0.19 11.1 0.1 1.8 1 1 0 1 1 1 0 Magnesium chelatase, subunit ChlI TsaE PF02367.17 AIN97600.1 - 0.087 12.8 0.0 0.17 11.9 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_18 PF13238.6 AIN97600.1 - 0.18 12.3 0.0 1 9.9 0.0 2.2 2 0 0 2 2 2 0 AAA domain Lipase_3 PF01764.25 AIN97601.1 - 3.5e-08 33.4 0.0 7.5e-08 32.3 0.0 1.6 1 0 0 1 1 1 1 Lipase (class 3) Hydrolase_4 PF12146.8 AIN97601.1 - 3.2e-05 23.3 0.7 6.8e-05 22.3 0.1 1.8 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 AIN97601.1 - 0.00044 20.9 0.2 0.00044 20.9 0.2 3.7 3 1 1 5 5 5 1 Alpha/beta hydrolase family DUF2974 PF11187.8 AIN97601.1 - 0.00058 19.5 0.2 0.0023 17.5 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF2974) Abhydrolase_5 PF12695.7 AIN97601.1 - 0.0053 16.5 0.0 0.014 15.1 0.0 1.7 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 AIN97601.1 - 0.017 14.8 0.0 0.037 13.7 0.0 1.5 1 0 0 1 1 1 0 alpha/beta hydrolase fold Thioesterase PF00975.20 AIN97601.1 - 0.019 15.1 0.0 0.045 13.9 0.0 1.6 1 0 0 1 1 1 0 Thioesterase domain CytochromB561_N PF09786.9 AIN97601.1 - 0.041 12.9 0.0 0.066 12.2 0.0 1.2 1 0 0 1 1 1 0 Cytochrome B561, N terminal PGAP1 PF07819.13 AIN97601.1 - 0.064 13.0 0.0 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 PGAP1-like protein LAP1C PF05609.12 AIN97601.1 - 0.2 10.7 0.1 0.36 9.9 0.1 1.3 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) Amastin PF07344.11 AIN97602.1 - 1.2e-49 168.1 9.8 1.5e-49 167.8 9.8 1.1 1 0 0 1 1 1 1 Amastin surface glycoprotein YwiC PF14256.6 AIN97602.1 - 1.5 9.2 13.7 0.28 11.5 1.7 3.0 2 1 1 3 3 3 0 YwiC-like protein Kinesin PF00225.23 AIN97604.1 - 3.4e-82 276.1 0.0 4.8e-82 275.6 0.0 1.2 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 AIN97604.1 - 2.4e-22 79.5 0.0 3e-20 72.7 0.0 2.3 2 0 0 2 2 2 2 Microtubule binding DEAD PF00270.29 AIN97605.1 - 4.7e-05 23.2 0.0 9e-05 22.3 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 AIN97605.1 - 9.8e-05 22.7 0.0 0.00085 19.6 0.0 2.5 3 0 0 3 3 3 1 Helicase conserved C-terminal domain AAA_7 PF12775.7 AIN97605.1 - 0.0016 18.0 0.0 0.0043 16.6 0.0 1.6 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_30 PF13604.6 AIN97605.1 - 0.041 13.6 0.1 0.087 12.5 0.1 1.5 1 0 0 1 1 1 0 AAA domain PRY PF13765.6 AIN97605.1 - 0.13 11.9 0.6 4.1 7.1 0.0 3.0 3 0 0 3 3 3 0 SPRY-associated domain UQ_con PF00179.26 AIN97606.1 - 1.4e-15 57.1 0.1 1.5e-15 57.0 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Acyltransferase PF01553.21 AIN97607.1 - 1.6e-17 63.4 0.0 3.3e-17 62.4 0.0 1.5 1 0 0 1 1 1 1 Acyltransferase SBDS_C PF09377.10 AIN97609.1 - 1.6e-25 89.4 0.1 3.6e-25 88.2 0.1 1.6 1 0 0 1 1 1 1 SBDS protein C-terminal domain SBDS PF01172.18 AIN97609.1 - 1.2e-23 83.0 0.4 1.2e-23 83.0 0.4 1.8 2 0 0 2 2 2 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein CH_2 PF06294.11 AIN97610.1 - 1e-30 105.7 0.0 1.7e-30 105.0 0.0 1.4 1 0 0 1 1 1 1 CH-like domain in sperm protein CAMSAP_CH PF11971.8 AIN97610.1 - 2.5e-19 68.9 0.0 4.4e-19 68.1 0.0 1.4 1 0 0 1 1 1 1 CAMSAP CH domain TMF_DNA_bd PF12329.8 AIN97610.1 - 0.048 13.7 0.7 0.32 11.0 0.6 2.0 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding Csm1_N PF18504.1 AIN97610.1 - 0.56 10.6 4.6 0.39 11.1 2.0 2.1 2 0 0 2 2 2 0 Csm1 N-terminal domain Dus PF01207.17 AIN97612.1 - 9.9e-54 182.5 0.0 3.2e-51 174.3 0.0 2.3 1 1 0 1 1 1 1 Dihydrouridine synthase (Dus) His_biosynth PF00977.21 AIN97612.1 - 1.9e-05 24.3 0.0 3.7e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 Histidine biosynthesis protein ThiG PF05690.14 AIN97612.1 - 0.0039 16.6 0.0 0.0064 15.8 0.0 1.3 1 0 0 1 1 1 1 Thiazole biosynthesis protein ThiG BMC PF00936.19 AIN97612.1 - 0.04 13.9 1.0 0.061 13.3 0.0 1.8 2 0 0 2 2 2 0 BMC domain BKACE PF05853.12 AIN97612.1 - 0.1 11.9 0.0 0.26 10.6 0.0 1.6 2 0 0 2 2 2 0 beta-keto acid cleavage enzyme NMO PF03060.15 AIN97612.1 - 0.16 11.4 0.1 0.28 10.5 0.1 1.3 1 0 0 1 1 1 0 Nitronate monooxygenase DUF167 PF02594.16 AIN97614.1 - 1.5e-12 47.4 0.1 1.9e-08 34.3 0.0 2.4 2 0 0 2 2 2 2 Uncharacterised ACR, YggU family COG1872 Cnn_1N PF07989.11 AIN97616.1 - 0.00033 20.8 3.8 0.00033 20.8 3.8 7.3 3 2 2 5 5 5 2 Centrosomin N-terminal motif 1 Rootletin PF15035.6 AIN97616.1 - 0.005 16.9 8.4 0.005 16.9 8.4 4.4 1 1 3 4 4 4 1 Ciliary rootlet component, centrosome cohesion DUF5550 PF17704.1 AIN97616.1 - 0.0068 16.5 0.1 0.028 14.6 0.1 2.0 1 0 0 1 1 1 1 Family of unknown function (DUF5550) KxDL PF10241.9 AIN97616.1 - 0.012 15.8 9.1 0.012 15.8 9.1 5.0 3 2 2 5 5 5 0 Uncharacterized conserved protein HALZ PF02183.18 AIN97616.1 - 0.15 12.3 0.3 0.15 12.3 0.3 7.1 7 1 0 7 7 7 0 Homeobox associated leucine zipper Baculo_PEP_C PF04513.12 AIN97616.1 - 7.8 6.5 31.4 7.4 6.6 12.3 4.4 2 2 2 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus HA2 PF04408.23 AIN97619.1 - 1.3e-12 48.0 0.0 4.7e-12 46.2 0.0 2.0 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.31 AIN97619.1 - 4.4e-11 43.1 0.0 1.7e-10 41.2 0.0 2.0 1 1 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 AIN97619.1 - 6.3e-08 32.6 0.1 2.2e-07 30.8 0.1 2.0 1 0 0 1 1 1 1 DEAD/DEAH box helicase dsrm PF00035.26 AIN97619.1 - 0.0043 17.7 0.3 0.079 13.7 0.1 2.6 2 0 0 2 2 2 1 Double-stranded RNA binding motif AAA_22 PF13401.6 AIN97619.1 - 0.0051 17.1 0.1 0.018 15.3 0.1 1.9 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 AIN97619.1 - 0.0086 15.2 0.0 0.019 14.0 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein Rad17 PF03215.15 AIN97619.1 - 0.12 12.2 0.0 0.23 11.3 0.0 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain ATPase PF06745.13 AIN97619.1 - 0.21 10.9 0.0 0.43 9.9 0.0 1.4 1 0 0 1 1 1 0 KaiC RACo_C_ter PF14574.6 AIN97621.1 - 0.052 12.6 0.5 0.14 11.1 0.2 1.8 2 0 0 2 2 2 0 C-terminal domain of RACo the ASKHA domain Amastin PF07344.11 AIN97622.1 - 2.3e-47 160.7 13.9 2.8e-47 160.4 13.9 1.1 1 0 0 1 1 1 1 Amastin surface glycoprotein HlyIII PF03006.20 AIN97622.1 - 0.43 10.2 10.2 1.1 8.9 10.2 1.9 1 1 0 1 1 1 0 Haemolysin-III related Amastin PF07344.11 AIN97623.1 - 3.4e-45 153.7 4.2 3.9e-45 153.5 4.2 1.0 1 0 0 1 1 1 1 Amastin surface glycoprotein Claudin_2 PF13903.6 AIN97623.1 - 0.0063 16.3 0.2 0.0063 16.3 0.2 1.9 2 0 0 2 2 2 1 PMP-22/EMP/MP20/Claudin tight junction SUR7 PF06687.12 AIN97623.1 - 0.28 10.8 9.7 0.74 9.4 5.8 2.1 2 0 0 2 2 2 0 SUR7/PalI family FGFR3_TM PF18123.1 AIN97623.1 - 1.1 8.9 0.1 1.1 8.9 0.1 4.1 4 0 0 4 4 4 0 Fibroblast growth factor receptor 3 transmembrane domain DUF1467 PF07330.12 AIN97623.1 - 1.1 9.2 8.1 4.9 7.1 2.3 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF1467) Phage_holin_3_6 PF07332.11 AIN97623.1 - 1.4 8.9 7.8 1.3 9.1 3.6 2.2 2 0 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III Ac76 PF05814.11 AIN97623.1 - 8.4 6.5 6.1 10 6.2 0.5 2.3 2 0 0 2 2 2 0 Orf76 (Ac76) Exo_endo_phos PF03372.23 AIN97624.1 - 0.00032 20.3 0.0 0.00073 19.1 0.0 1.5 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family YabA PF06156.13 AIN97625.1 - 0.14 12.8 3.6 0.17 12.6 1.1 2.4 2 0 0 2 2 2 0 Initiation control protein YabA DUF2052 PF09747.9 AIN97625.1 - 0.65 10.1 8.3 0.53 10.4 0.2 3.3 3 0 0 3 3 3 0 Coiled-coil domain containing protein (DUF2052) DNA_pol_A_exo1 PF01612.20 AIN97626.1 - 8.5e-14 51.6 0.0 2.3e-13 50.2 0.0 1.7 2 0 0 2 2 2 1 3'-5' exonuclease LZ3wCH PF18517.1 AIN97626.1 - 0.005 16.9 0.7 0.021 14.9 0.7 2.0 1 0 0 1 1 1 1 Leucine zipper with capping helix domain zf-CCCH PF00642.24 AIN97626.1 - 0.0078 16.1 0.7 0.0078 16.1 0.7 1.9 2 0 0 2 2 2 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) NIF PF03031.18 AIN97628.1 - 1.2e-30 106.3 0.0 1.9e-28 99.2 0.0 3.0 2 1 0 2 2 2 1 NLI interacting factor-like phosphatase Ntox34 PF15606.6 AIN97628.1 - 0.051 13.7 0.0 0.11 12.6 0.0 1.5 1 0 0 1 1 1 0 Bacterial toxin 34 DUF2608 PF11019.8 AIN97628.1 - 0.082 12.4 0.2 7.8 5.9 0.0 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF2608) BtrH_N PF14399.6 AIN97628.1 - 0.09 13.0 0.0 0.17 12.1 0.0 1.4 1 0 0 1 1 1 0 Butirosin biosynthesis protein H, N-terminal DNA_pol_A PF00476.20 AIN97629.1 - 2.8e-95 319.5 0.0 6.2e-83 278.9 0.0 2.2 2 0 0 2 2 2 2 DNA polymerase family A Piezo_RRas_bdg PF12166.8 AIN97630.1 - 5.5e-90 302.7 0.0 7.4e-90 302.3 0.0 1.2 1 0 0 1 1 1 1 Piezo non-specific cation channel, R-Ras-binding domain DUF5330 PF17264.2 AIN97630.1 - 0.04 13.9 0.0 0.089 12.8 0.0 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5330) LRR_6 PF13516.6 AIN97632.1 - 0.00054 19.8 0.9 15 6.0 0.0 5.6 5 0 0 5 5 5 2 Leucine Rich repeat Calpain_inhib PF00748.19 AIN97632.1 - 0.91 10.0 3.2 1.1 9.8 0.3 2.3 2 0 0 2 2 2 0 Calpain inhibitor OsmC PF02566.19 AIN97633.1 - 2.9e-06 27.7 0.5 5.8e-06 26.7 0.5 1.5 1 0 0 1 1 1 1 OsmC-like protein SelB-wing_2 PF09106.11 AIN97634.1 - 4.1 7.7 5.1 7 6.9 0.1 3.1 3 0 0 3 3 3 0 Elongation factor SelB, winged helix BCS1_N PF08740.11 AIN97636.1 - 8e-31 107.5 3.2 1.6e-30 106.5 3.2 1.5 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.29 AIN97636.1 - 7e-20 71.8 0.0 1.9e-19 70.4 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 AIN97636.1 - 0.00078 19.9 0.4 0.013 15.9 0.0 2.3 1 1 1 2 2 2 1 AAA ATPase domain AAA_5 PF07728.14 AIN97636.1 - 0.00086 19.3 0.4 0.013 15.5 0.2 2.7 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 AIN97636.1 - 0.0013 18.5 0.0 0.0029 17.4 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain DUF815 PF05673.13 AIN97636.1 - 0.002 17.3 0.1 0.0045 16.2 0.0 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF815) Rad17 PF03215.15 AIN97636.1 - 0.0026 17.7 0.0 0.012 15.6 0.0 2.1 2 1 1 3 3 3 1 Rad17 P-loop domain AAA_11 PF13086.6 AIN97636.1 - 0.0037 17.1 0.0 0.0072 16.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.27 AIN97636.1 - 0.0039 17.7 0.0 0.009 16.5 0.0 1.6 1 0 0 1 1 1 1 ABC transporter AAA_18 PF13238.6 AIN97636.1 - 0.0059 17.1 0.0 0.014 15.9 0.0 1.6 2 0 0 2 2 1 1 AAA domain RNA_helicase PF00910.22 AIN97636.1 - 0.0082 16.5 0.0 0.022 15.1 0.0 1.8 1 0 0 1 1 1 1 RNA helicase AAA_33 PF13671.6 AIN97636.1 - 0.019 15.1 0.0 0.038 14.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 AIN97636.1 - 0.03 14.6 0.0 0.2 11.9 0.0 2.2 2 1 0 2 2 2 0 AAA domain NACHT PF05729.12 AIN97636.1 - 0.064 13.2 0.0 0.19 11.6 0.0 1.8 1 0 0 1 1 1 0 NACHT domain AAA_25 PF13481.6 AIN97636.1 - 0.065 12.8 0.4 0.26 10.9 0.2 2.2 2 1 0 2 2 2 0 AAA domain TIP49 PF06068.13 AIN97636.1 - 0.16 11.2 0.0 0.27 10.4 0.0 1.3 1 0 0 1 1 1 0 TIP49 P-loop domain ATPase_2 PF01637.18 AIN97636.1 - 0.16 11.9 0.0 7.9 6.3 0.0 2.3 1 1 1 2 2 2 0 ATPase domain predominantly from Archaea Syntaxin PF00804.25 AIN97638.1 - 0.12 12.0 0.1 0.21 11.2 0.1 1.3 1 0 0 1 1 1 0 Syntaxin KAR9 PF08580.10 AIN97638.1 - 2.5 6.5 13.7 4.4 5.7 13.7 1.3 1 0 0 1 1 1 0 Yeast cortical protein KAR9 MAP65_ASE1 PF03999.12 AIN97638.1 - 4.4 5.9 8.9 3.1 6.4 0.0 2.2 2 0 0 2 2 2 0 Microtubule associated protein (MAP65/ASE1 family) Nup188 PF10487.9 AIN97639.1 - 0.00078 17.5 0.0 0.0013 16.8 0.0 1.2 1 0 0 1 1 1 1 Nucleoporin subcomplex protein binding to Pom34 DUF2220 PF09983.9 AIN97640.1 - 0.0039 16.6 1.0 0.0039 16.6 1.0 1.7 2 0 0 2 2 2 1 Uncharacterized protein conserved in bacteria C-term(DUF2220) DUF1664 PF07889.12 AIN97640.1 - 3.2 7.8 4.8 8.2 6.5 0.1 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) Mobilization_B PF17511.2 AIN97641.1 - 0.057 13.8 1.5 0.21 11.9 1.5 2.0 1 0 0 1 1 1 0 Mobilization protein B VPS13 PF16908.5 AIN97642.1 - 5.2e-34 118.1 0.3 3.5e-33 115.4 0.3 2.2 1 1 0 1 1 1 1 Vacuolar sorting-associated protein 13, N-terminal Chorein_N PF12624.7 AIN97642.1 - 1.3e-27 96.3 0.0 2.9e-27 95.1 0.0 1.7 1 0 0 1 1 1 1 N-terminal region of Chorein or VPS13 SHR-BD PF06650.12 AIN97642.1 - 4.5e-16 59.0 0.0 3.5e-11 43.0 0.0 3.3 2 1 0 2 2 2 2 SHR-binding domain of vacuolar-sorting associated protein 13 2-Hacid_dh_C PF02826.19 AIN97643.1 - 4.3e-45 153.3 0.0 5e-45 153.0 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AdoHcyase_NAD PF00670.21 AIN97643.1 - 1.7e-06 28.2 0.3 3.3e-06 27.2 0.3 1.4 1 1 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain NAD_binding_2 PF03446.15 AIN97643.1 - 9.2e-05 22.7 0.1 0.00013 22.2 0.1 1.1 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase IlvN PF07991.12 AIN97643.1 - 0.0001 21.9 0.0 0.00014 21.5 0.0 1.2 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain AlaDh_PNT_C PF01262.21 AIN97643.1 - 0.00023 20.5 0.0 0.00038 19.8 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain F420_oxidored PF03807.17 AIN97643.1 - 0.0025 18.3 0.3 0.0063 17.1 0.2 1.6 1 1 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent ELFV_dehydrog PF00208.21 AIN97643.1 - 0.026 14.2 0.0 0.041 13.6 0.0 1.3 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Pyr_redox PF00070.27 AIN97643.1 - 0.039 14.5 0.2 0.077 13.6 0.2 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase DpaA_N PF16924.5 AIN97643.1 - 0.15 12.2 0.0 0.63 10.1 0.0 1.9 2 0 0 2 2 2 0 Dipicolinate synthase subunit A N-terminal domain DUF1143 PF06608.11 AIN97644.1 - 0.037 14.1 0.0 0.07 13.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1143) PTEN_C2 PF10409.9 AIN97645.1 - 8.4e-10 38.5 0.0 1.5e-09 37.7 0.0 1.4 1 0 0 1 1 1 1 C2 domain of PTEN tumour-suppressor protein DSPc PF00782.20 AIN97645.1 - 4.2e-08 33.1 0.1 7.8e-08 32.2 0.1 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 AIN97645.1 - 0.00023 20.8 0.0 0.00045 19.9 0.0 1.4 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.6 AIN97645.1 - 0.0076 16.2 0.1 0.015 15.3 0.1 1.5 1 0 0 1 1 1 1 Tyrosine phosphatase family PTPlike_phytase PF14566.6 AIN97645.1 - 0.078 13.1 0.1 0.14 12.3 0.1 1.3 1 0 0 1 1 1 0 Inositol hexakisphosphate CDKN3 PF05706.12 AIN97645.1 - 0.16 11.6 0.2 0.3 10.8 0.2 1.4 1 0 0 1 1 1 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) C2 PF00168.30 AIN97646.1 - 0.034 14.5 0.0 4.6 7.6 0.0 3.6 2 1 0 2 2 2 0 C2 domain R3H-assoc PF13902.6 AIN97647.1 - 2.2e-17 63.7 0.2 4.1e-17 62.8 0.2 1.5 1 0 0 1 1 1 1 R3H-associated N-terminal domain R3H PF01424.22 AIN97647.1 - 0.015 15.2 0.0 0.048 13.7 0.0 1.8 1 0 0 1 1 1 0 R3H domain EAP30 PF04157.16 AIN97649.1 - 1.1e-61 208.1 6.2 1.9e-61 207.4 6.2 1.4 1 1 0 1 1 1 1 EAP30/Vps36 family MitMem_reg PF13012.6 AIN97649.1 - 0.049 14.1 0.4 0.43 11.0 0.1 2.1 2 0 0 2 2 2 0 Maintenance of mitochondrial structure and function HalX PF08663.10 AIN97649.1 - 0.11 12.9 0.4 0.27 11.6 0.4 1.7 1 0 0 1 1 1 0 HalX domain MerR-DNA-bind PF09278.11 AIN97649.1 - 0.29 11.7 4.5 0.78 10.3 4.5 1.7 1 0 0 1 1 1 0 MerR, DNA binding DUF3808 PF10300.9 AIN97652.1 - 1e-40 139.9 0.8 2.5e-40 138.7 0.8 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3808) UPF0242 PF06785.11 AIN97653.1 - 0.15 12.2 2.5 0.15 12.1 0.8 1.7 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus p25-alpha PF05517.12 AIN97654.1 - 2.4e-32 112.3 3.0 2.7e-32 112.1 3.0 1.0 1 0 0 1 1 1 1 p25-alpha ERAP1_C PF11838.8 AIN97654.1 - 0.054 13.0 0.0 0.063 12.8 0.0 1.1 1 0 0 1 1 1 0 ERAP1-like C-terminal domain Amastin PF07344.11 AIN97655.1 - 5.1e-47 159.6 14.5 6.1e-47 159.3 14.5 1.1 1 0 0 1 1 1 1 Amastin surface glycoprotein Amastin PF07344.11 AIN97656.1 - 7.2e-51 172.1 8.0 8.7e-51 171.8 8.0 1.1 1 0 0 1 1 1 1 Amastin surface glycoprotein FGFR3_TM PF18123.1 AIN97656.1 - 0.39 10.3 0.2 0.39 10.3 0.2 3.8 4 0 0 4 4 4 0 Fibroblast growth factor receptor 3 transmembrane domain Amastin PF07344.11 AIN97658.1 - 1.7e-48 164.4 17.1 2.1e-48 164.1 17.1 1.1 1 0 0 1 1 1 1 Amastin surface glycoprotein EVC2_like PF12297.8 AIN97658.1 - 0.12 11.0 0.1 4.8 5.8 0.0 2.1 2 0 0 2 2 2 0 Ellis van Creveld protein 2 like protein DUF4293 PF14126.6 AIN97658.1 - 0.13 12.5 6.1 0.39 10.9 6.1 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4293) FGFR3_TM PF18123.1 AIN97658.1 - 0.38 10.3 0.2 0.38 10.3 0.2 4.1 4 0 0 4 4 4 0 Fibroblast growth factor receptor 3 transmembrane domain DUF4834 PF16118.5 AIN97658.1 - 2.8 9.0 0.0 2.8 9.0 0.0 2.8 3 1 0 3 3 3 0 Domain of unknown function (DUF4834) Amastin PF07344.11 AIN97659.1 - 5.6e-52 175.7 10.9 6.6e-52 175.5 10.9 1.0 1 0 0 1 1 1 1 Amastin surface glycoprotein DUF1467 PF07330.12 AIN97659.1 - 0.28 11.1 6.2 7.9 6.5 0.0 3.6 3 1 1 4 4 4 0 Protein of unknown function (DUF1467) DUF4064 PF13273.6 AIN97659.1 - 0.56 10.5 0.0 0.56 10.5 0.0 3.4 2 1 1 3 3 3 0 Protein of unknown function (DUF4064) Vpu PF00558.19 AIN97659.1 - 2.8 7.8 4.7 3.3 7.5 0.6 2.8 2 1 1 3 3 3 0 Vpu protein CrgA PF06781.12 AIN97659.1 - 3.1 7.9 5.5 0.92 9.6 1.6 2.1 1 1 1 2 2 2 0 Cell division protein CrgA Zeta_toxin PF06414.12 AIN97660.1 - 9.5e-11 41.3 0.0 2.7e-10 39.9 0.0 1.7 1 0 0 1 1 1 1 Zeta toxin AAA_33 PF13671.6 AIN97660.1 - 0.0083 16.3 0.0 0.022 14.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 AIN97660.1 - 0.082 13.5 0.0 0.79 10.3 0.0 2.3 2 0 0 2 2 2 0 AAA domain Peptidase_C15 PF01470.17 AIN97661.1 - 2.8e-10 40.7 0.6 0.00053 20.2 0.1 2.2 2 0 0 2 2 2 2 Pyroglutamyl peptidase DUF2236 PF09995.9 AIN97662.1 - 0.057 13.6 4.0 0.059 13.6 2.2 1.8 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2236) RCC1 PF00415.18 AIN97663.1 - 1.1e-21 77.2 1.3 1.7e-07 31.7 0.1 4.6 4 0 0 4 4 4 4 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 AIN97663.1 - 1.8e-16 59.5 11.4 3.6e-10 39.4 1.7 5.5 5 0 0 5 5 5 4 Regulator of chromosome condensation (RCC1) repeat Paralemmin PF03285.15 AIN97663.1 - 0.005 16.5 2.0 0.012 15.2 2.0 1.7 1 0 0 1 1 1 1 Paralemmin TPR_12 PF13424.6 AIN97664.1 - 4.8e-06 26.8 1.8 0.0021 18.3 0.4 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat IQ PF00612.27 AIN97664.1 - 0.0017 18.0 0.3 0.0017 18.0 0.3 7.7 7 1 1 8 8 8 3 IQ calmodulin-binding motif TMEM239 PF15841.5 AIN97664.1 - 0.48 10.3 2.6 2.1 8.2 0.5 2.5 2 0 0 2 2 2 0 Transmembrane protein 239 family DEAD PF00270.29 AIN97666.1 - 1.6e-45 155.0 0.0 1.3e-44 152.0 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 AIN97666.1 - 2.8e-24 85.6 0.0 8.5e-24 84.0 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DBP10CT PF08147.12 AIN97666.1 - 5.3e-11 42.6 2.8 1.4e-10 41.3 2.8 1.8 1 0 0 1 1 1 1 DBP10CT (NUC160) domain ResIII PF04851.15 AIN97666.1 - 3.3e-05 24.0 0.0 0.00016 21.7 0.0 2.1 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 AIN97666.1 - 0.1 12.9 1.2 1 9.6 0.2 3.0 2 1 0 2 2 2 0 AAA domain FtsX PF02687.21 AIN97668.1 - 4.8e-14 52.6 20.1 4.2e-10 40.0 6.1 6.6 6 1 0 6 6 6 2 FtsX-like permease family Fez1 PF06818.15 AIN97669.1 - 0.0033 17.9 21.4 0.025 15.0 11.1 3.4 2 1 1 3 3 3 3 Fez1 MIP-T3_C PF17749.1 AIN97669.1 - 5.4 7.0 8.6 0.64 10.0 2.8 2.5 2 0 0 2 2 2 0 Microtubule-binding protein MIP-T3 C-terminal region Pkinase PF00069.25 AIN97670.1 - 8.6e-55 185.9 0.0 1.2e-54 185.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 AIN97670.1 - 4e-31 108.2 0.0 7.1e-31 107.4 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 AIN97670.1 - 0.0026 17.1 0.0 0.0037 16.6 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Glyco_hydro_4C PF11975.8 AIN97670.1 - 0.049 13.7 0.1 0.093 12.8 0.1 1.5 1 0 0 1 1 1 0 Family 4 glycosyl hydrolase C-terminal domain Orthopox_A5L PF06193.11 AIN97670.1 - 0.068 12.6 0.0 0.14 11.6 0.0 1.6 1 0 0 1 1 1 0 Orthopoxvirus A5L protein-like Pkinase_fungal PF17667.1 AIN97670.1 - 0.12 11.1 0.0 0.2 10.4 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase PLDc_2 PF13091.6 AIN97672.1 - 4.2e-31 107.6 0.0 1.7e-23 82.9 0.0 2.4 2 0 0 2 2 2 2 PLD-like domain PLDc PF00614.22 AIN97672.1 - 1.4e-05 25.1 0.6 0.016 15.4 0.2 2.6 2 0 0 2 2 2 2 Phospholipase D Active site motif ubiquitin PF00240.23 AIN97674.1 - 4e-16 58.5 0.0 4.5e-16 58.4 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 AIN97674.1 - 4.5e-07 29.6 0.0 4.9e-07 29.5 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Rad60-SLD_2 PF13881.6 AIN97674.1 - 0.00067 19.7 0.1 0.0015 18.6 0.1 1.6 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_5 PF18037.1 AIN97674.1 - 0.0035 17.6 0.0 0.0038 17.6 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-like domain Ubiquitin_2 PF14560.6 AIN97674.1 - 0.033 14.6 0.0 0.067 13.6 0.0 1.6 1 1 0 1 1 1 0 Ubiquitin-like domain DoxX PF07681.12 AIN97675.1 - 0.0018 18.8 5.8 0.005 17.4 5.8 1.7 1 1 0 1 1 1 1 DoxX HR_lesion PF05514.11 AIN97675.1 - 0.011 16.0 2.7 0.015 15.5 2.7 1.3 1 1 0 1 1 1 0 HR-like lesion-inducing TctB PF07331.11 AIN97675.1 - 0.61 10.3 8.2 0.87 9.9 7.5 1.6 1 1 1 2 2 2 0 Tripartite tricarboxylate transporter TctB family SIR2 PF02146.17 AIN97676.1 - 4.7e-46 156.9 0.0 5.9e-46 156.6 0.0 1.1 1 0 0 1 1 1 1 Sir2 family Sulfotransfer_1 PF00685.27 AIN97676.1 - 0.15 11.5 0.1 0.28 10.6 0.0 1.5 2 0 0 2 2 2 0 Sulfotransferase domain Pkinase PF00069.25 AIN97677.1 - 8.7e-45 153.1 0.0 7.1e-44 150.1 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 AIN97677.1 - 9.3e-25 87.4 0.0 1e-21 77.4 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Kdo PF06293.14 AIN97677.1 - 0.0084 15.5 0.0 0.016 14.6 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family OGG_N PF07934.12 AIN97679.1 - 1.2e-29 102.8 0.2 2.3e-29 101.9 0.2 1.4 1 0 0 1 1 1 1 8-oxoguanine DNA glycosylase, N-terminal domain HhH-GPD PF00730.25 AIN97679.1 - 7.6e-10 39.2 0.0 1.2e-08 35.4 0.0 2.2 1 1 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.23 AIN97679.1 - 0.00036 20.2 0.0 0.0016 18.2 0.0 2.1 2 0 0 2 2 2 1 Helix-hairpin-helix motif Pkinase PF00069.25 AIN97681.1 - 1.6e-50 171.9 0.0 1e-24 87.3 0.0 2.8 3 0 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 AIN97681.1 - 4.9e-29 101.4 0.0 1.7e-16 60.3 0.0 2.6 2 1 0 2 2 2 2 Protein tyrosine kinase DSPc PF00782.20 AIN97681.1 - 3.5e-26 91.6 0.0 6.3e-26 90.8 0.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain LRR_8 PF13855.6 AIN97681.1 - 1.2e-11 44.1 6.9 1.4e-09 37.5 4.0 3.8 4 0 0 4 4 4 1 Leucine rich repeat LRR_4 PF12799.7 AIN97681.1 - 1.5e-07 31.6 8.9 0.00064 20.1 1.4 4.1 3 1 1 4 4 4 3 Leucine Rich repeats (2 copies) Kinase-like PF14531.6 AIN97681.1 - 0.001 18.5 0.0 0.15 11.4 0.0 2.3 2 0 0 2 2 2 2 Kinase-like Y_phosphatase PF00102.27 AIN97681.1 - 0.0012 18.5 0.0 0.0021 17.6 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase ZZ PF00569.17 AIN97681.1 - 0.092 12.6 3.4 0.27 11.1 3.4 1.8 1 0 0 1 1 1 0 Zinc finger, ZZ type LRR_1 PF00560.33 AIN97681.1 - 0.51 11.1 5.8 1.9e+02 3.3 0.1 5.6 5 0 0 5 5 5 0 Leucine Rich Repeat zf-UBR PF02207.20 AIN97681.1 - 6.4 7.0 7.7 1.4 9.2 3.8 2.0 2 0 0 2 2 2 0 Putative zinc finger in N-recognin (UBR box) Thioredoxin PF00085.20 AIN97682.1 - 3.4e-25 88.0 0.0 2.5e-24 85.2 0.0 2.2 2 0 0 2 2 2 1 Thioredoxin Thioredoxin_2 PF13098.6 AIN97682.1 - 2.9e-08 34.1 0.2 1.4e-06 28.7 0.1 3.2 3 1 0 3 3 3 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 AIN97682.1 - 4.9e-06 26.8 0.1 0.0042 17.4 0.0 3.6 4 1 1 5 5 5 1 Thioredoxin-like Redoxin PF08534.10 AIN97682.1 - 0.00045 19.9 0.1 0.002 17.9 0.0 2.0 2 1 0 2 2 2 1 Redoxin TraF PF13728.6 AIN97682.1 - 0.0011 18.8 0.0 0.0092 15.8 0.0 2.3 2 0 0 2 2 2 1 F plasmid transfer operon protein AhpC-TSA PF00578.21 AIN97682.1 - 0.0016 18.4 0.0 0.0062 16.4 0.0 2.0 2 0 0 2 2 2 1 AhpC/TSA family Thioredoxin_6 PF13848.6 AIN97682.1 - 0.0021 18.0 0.0 0.009 15.9 0.0 2.1 2 1 0 2 2 2 1 Thioredoxin-like domain Thioredoxin_7 PF13899.6 AIN97682.1 - 0.0024 18.0 0.0 0.0058 16.8 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_9 PF14595.6 AIN97682.1 - 0.0063 16.3 0.0 0.014 15.2 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin OST3_OST6 PF04756.13 AIN97682.1 - 0.03 13.7 0.0 0.063 12.6 0.0 1.5 1 0 0 1 1 1 0 OST3 / OST6 family, transporter family SUKH-3 PF14433.6 AIN97682.1 - 0.044 14.2 0.0 0.088 13.3 0.0 1.5 1 0 0 1 1 1 0 SUKH-3 immunity protein PRIMA1 PF16101.5 AIN97683.1 - 4.8 7.2 14.1 0.53 10.3 5.8 3.0 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 CAP_N PF01213.19 AIN97683.1 - 5.7 6.3 12.0 2.6 7.4 5.1 2.4 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal Exo_endo_phos PF03372.23 AIN97684.1 - 3.7e-16 59.3 0.0 5.8e-15 55.4 0.0 2.7 2 1 0 2 2 2 1 Endonuclease/Exonuclease/phosphatase family zf_PR_Knuckle PF18445.1 AIN97684.1 - 0.045 13.6 0.2 0.13 12.0 0.2 1.8 1 0 0 1 1 1 0 PR zinc knuckle motif DUF2755 PF10954.8 AIN97685.1 - 0.06 13.3 3.0 0.058 13.3 1.0 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF2755) Glyco_hydro_65m PF03632.15 AIN97686.1 - 1.7e-40 139.1 0.0 2.4e-40 138.6 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 65 central catalytic domain Glyco_hydro_65C PF03633.15 AIN97686.1 - 5.8e-08 32.5 0.1 1.2e-07 31.5 0.1 1.6 1 0 0 1 1 1 1 Glycosyl hydrolase family 65, C-terminal domain Glyco_hydro_65N PF03636.15 AIN97686.1 - 0.0079 15.9 0.0 0.014 15.0 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 65, N-terminal domain Kelch_5 PF13854.6 AIN97687.1 - 1.7e-12 47.0 8.8 2e-05 24.5 0.2 6.0 6 0 0 6 6 6 4 Kelch motif Kelch_1 PF01344.25 AIN97687.1 - 7.6e-12 44.6 4.1 5.5e-05 22.7 0.1 4.8 4 0 0 4 4 4 3 Kelch motif Kelch_3 PF13415.6 AIN97687.1 - 4.1e-11 42.9 18.1 2.1e-06 27.9 0.1 8.1 10 0 0 10 10 10 2 Galactose oxidase, central domain Kelch_4 PF13418.6 AIN97687.1 - 4.5e-11 42.6 12.3 2e-06 27.7 0.1 5.9 6 0 0 6 6 6 3 Galactose oxidase, central domain Kelch_6 PF13964.6 AIN97687.1 - 5.1e-08 32.9 1.8 0.0057 16.9 0.0 5.1 5 0 0 5 5 5 2 Kelch motif Kelch_2 PF07646.15 AIN97687.1 - 6.3e-06 25.9 7.5 0.52 10.4 0.0 5.6 5 0 0 5 5 5 2 Kelch motif HA2 PF04408.23 AIN97688.1 - 4.6e-16 59.0 0.0 9.9e-16 58.0 0.0 1.6 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.31 AIN97688.1 - 1.4e-11 44.7 0.0 5.3e-11 42.9 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain OB_NTP_bind PF07717.16 AIN97688.1 - 1.4e-10 41.4 0.0 5.5e-10 39.5 0.0 2.1 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold DEAD PF00270.29 AIN97688.1 - 8.2e-08 32.2 0.3 1.7e-07 31.1 0.3 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_19 PF13245.6 AIN97688.1 - 2e-06 28.2 0.2 4.5e-06 27.1 0.2 1.5 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 AIN97688.1 - 1.3e-05 25.4 0.0 3.3e-05 24.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 AIN97688.1 - 0.00033 20.4 0.0 0.00065 19.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain SRP54 PF00448.22 AIN97688.1 - 0.0019 17.9 0.2 0.0067 16.1 0.2 1.8 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain T2SSE PF00437.20 AIN97688.1 - 0.0023 17.0 0.0 0.0047 16.0 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_7 PF12775.7 AIN97688.1 - 0.0068 15.9 0.0 0.015 14.8 0.0 1.5 1 0 0 1 1 1 1 P-loop containing dynein motor region cobW PF02492.19 AIN97688.1 - 0.007 16.0 0.4 0.29 10.7 0.1 2.5 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_25 PF13481.6 AIN97688.1 - 0.015 14.8 0.0 0.035 13.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain Flavi_DEAD PF07652.14 AIN97688.1 - 0.019 14.9 0.2 0.04 13.9 0.2 1.5 1 0 0 1 1 1 0 Flavivirus DEAD domain AAA_16 PF13191.6 AIN97688.1 - 0.02 15.3 2.4 0.027 14.9 0.0 2.4 3 0 0 3 3 3 0 AAA ATPase domain NACHT PF05729.12 AIN97688.1 - 0.029 14.3 0.1 0.18 11.7 0.0 2.3 2 1 0 2 2 2 0 NACHT domain AAA_23 PF13476.6 AIN97688.1 - 0.038 14.5 0.0 0.066 13.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 AIN97688.1 - 0.042 13.6 0.0 0.11 12.2 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain ResIII PF04851.15 AIN97688.1 - 0.043 13.8 0.0 3.4 7.7 0.0 2.3 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit Helicase_RecD PF05127.14 AIN97688.1 - 0.14 12.0 0.0 0.27 11.1 0.0 1.4 1 0 0 1 1 1 0 Helicase Dynamin_N PF00350.23 AIN97689.1 - 3.3e-15 56.5 0.0 5.9e-14 52.5 0.0 2.4 1 1 0 1 1 1 1 Dynamin family DUF5600 PF18150.1 AIN97689.1 - 1.3e-11 45.0 0.1 2.6e-11 44.0 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF5600) MMR_HSR1 PF01926.23 AIN97689.1 - 1.2e-07 31.8 0.0 2.9e-07 30.6 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase EHD_N PF16880.5 AIN97689.1 - 1.1e-06 28.4 0.0 2e-06 27.6 0.0 1.4 1 0 0 1 1 1 1 N-terminal EH-domain containing protein RsgA_GTPase PF03193.16 AIN97689.1 - 0.086 12.7 0.1 2.5 8.0 0.0 2.8 4 0 0 4 4 4 0 RsgA GTPase Cofilin_ADF PF00241.20 AIN97691.1 - 3.3e-17 62.4 0.1 4.1e-11 42.7 0.0 2.2 2 0 0 2 2 2 2 Cofilin/tropomyosin-type actin-binding protein MMgT PF10270.9 AIN97694.1 - 0.0067 16.8 0.3 0.01 16.2 0.3 1.4 1 1 0 1 1 1 1 Membrane magnesium transporter Clat_adaptor_s PF01217.20 AIN97695.1 - 8.6e-51 171.6 4.2 9.5e-51 171.5 4.2 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain tRNA-synt_2 PF00152.20 AIN97696.1 - 4.4e-87 292.1 0.0 6.1e-87 291.6 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_synt_1c_R1 PF04558.15 AIN97696.1 - 2.7e-34 118.5 0.2 4.3e-34 117.9 0.2 1.3 1 0 0 1 1 1 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 tRNA_anti-codon PF01336.25 AIN97696.1 - 8.3e-10 38.5 0.0 2e-09 37.3 0.0 1.7 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain DUF1412 PF07203.11 AIN97697.1 - 0.21 11.8 0.1 0.35 11.1 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1412) DUF2046 PF09755.9 AIN97698.1 - 3.3e-06 26.6 26.8 5.5e-06 25.8 23.1 2.5 2 1 0 2 2 2 1 Uncharacterized conserved protein H4 (DUF2046) TMPIT PF07851.13 AIN97698.1 - 0.00069 19.0 15.9 0.03 13.6 6.6 2.2 2 0 0 2 2 2 2 TMPIT-like protein MscS_porin PF12795.7 AIN97698.1 - 0.0034 16.9 22.5 0.09 12.3 13.4 2.2 2 0 0 2 2 2 2 Mechanosensitive ion channel porin domain ATG16 PF08614.11 AIN97698.1 - 0.016 15.4 5.9 0.016 15.4 5.9 3.2 2 1 1 3 3 3 0 Autophagy protein 16 (ATG16) Exonuc_VII_L PF02601.15 AIN97698.1 - 0.024 14.2 13.7 0.16 11.5 7.4 2.1 2 0 0 2 2 2 0 Exonuclease VII, large subunit TrmB PF01978.19 AIN97698.1 - 0.069 13.0 0.4 0.22 11.5 0.4 1.8 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB Il2rg PF15874.5 AIN97698.1 - 0.51 10.6 5.2 0.9 9.8 0.4 2.9 2 2 1 3 3 3 0 Putative Interleukin 2 receptor, gamma chain Myosin_tail_1 PF01576.19 AIN97698.1 - 0.52 8.1 30.6 0.36 8.6 18.6 2.0 2 0 0 2 2 2 0 Myosin tail Atg14 PF10186.9 AIN97698.1 - 0.53 9.3 19.4 1.7 7.7 12.4 2.2 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 Prominin PF05478.11 AIN97698.1 - 5.1 4.9 11.3 0.52 8.2 6.0 1.7 2 0 0 2 2 2 0 Prominin CBFD_NFYB_HMF PF00808.23 AIN97699.1 - 1.1e-05 25.6 0.5 2e-05 24.8 0.5 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 AIN97699.1 - 0.00024 21.5 1.1 0.00029 21.2 0.1 1.7 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 DUF1931 PF09123.11 AIN97699.1 - 0.14 12.3 0.0 0.27 11.4 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1931) EF-hand_7 PF13499.6 AIN97701.1 - 1.7e-23 82.8 5.6 2.1e-15 56.9 1.1 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 AIN97701.1 - 4.3e-21 72.8 9.9 1.8e-07 30.2 1.4 3.6 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.6 AIN97701.1 - 4.2e-19 66.8 3.5 3.5e-06 26.5 0.1 3.5 3 0 0 3 3 3 3 EF-hand domain EF-hand_8 PF13833.6 AIN97701.1 - 1.2e-14 53.8 7.9 1.8e-11 43.7 0.8 3.3 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_9 PF14658.6 AIN97701.1 - 2.5e-13 50.1 0.2 1.4e-06 28.6 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 AIN97701.1 - 1.5e-12 46.4 4.9 0.00032 20.1 1.0 3.5 3 0 0 3 3 3 3 EF hand EF-hand_4 PF12763.7 AIN97701.1 - 1.4e-06 28.2 0.8 0.0048 16.8 0.2 2.2 2 0 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand Caleosin PF05042.13 AIN97701.1 - 0.00087 19.3 0.0 0.31 10.9 0.0 3.0 2 1 1 3 3 3 1 Caleosin related protein DUF3164 PF11363.8 AIN97701.1 - 0.0058 16.3 0.2 0.072 12.7 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF3164) EF-hand_14 PF17959.1 AIN97701.1 - 0.0079 16.5 3.3 0.35 11.3 0.3 2.3 1 1 0 2 2 2 1 EF-hand domain TerB PF05099.13 AIN97701.1 - 0.014 15.3 5.8 0.11 12.5 1.1 2.4 1 1 2 3 3 3 0 Tellurite resistance protein TerB MgtE_N PF03448.17 AIN97701.1 - 0.032 14.8 0.7 0.032 14.8 0.7 2.5 3 0 0 3 3 3 0 MgtE intracellular N domain SPARC_Ca_bdg PF10591.9 AIN97701.1 - 0.081 13.2 1.9 1 9.7 0.4 2.2 1 1 1 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region Dockerin_1 PF00404.18 AIN97701.1 - 0.083 13.1 0.0 0.21 11.8 0.0 1.7 1 0 0 1 1 1 0 Dockerin type I domain EF-hand_11 PF08976.11 AIN97701.1 - 0.13 13.1 0.5 0.42 11.5 0.1 1.9 2 0 0 2 2 2 0 EF-hand domain SurA_N_2 PF13623.6 AIN97701.1 - 0.13 12.1 5.2 1 9.2 0.6 2.4 1 1 1 2 2 2 0 SurA N-terminal domain DUF3911 PF13050.6 AIN97701.1 - 0.54 10.4 3.2 2.7 8.1 0.2 3.0 3 1 0 3 3 3 0 Protein of unknown function (DUF3911) Aminotran_4 PF01063.19 AIN97703.1 - 2.9e-35 122.1 0.0 3.7e-35 121.8 0.0 1.1 1 0 0 1 1 1 1 Amino-transferase class IV Glycos_transf_1 PF00534.20 AIN97704.1 - 3.2e-27 95.1 0.0 7.1e-27 94.0 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 AIN97704.1 - 3.1e-14 53.6 0.1 6.2e-13 49.3 0.0 2.3 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 AIN97704.1 - 6.8e-06 26.2 0.0 1.3e-05 25.2 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_1_2 PF13524.6 AIN97704.1 - 0.0034 17.7 0.0 0.0081 16.5 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferases group 1 DnaJ PF00226.31 AIN97705.1 - 6.1e-19 67.9 0.2 1.7e-18 66.5 0.2 1.8 1 0 0 1 1 1 1 DnaJ domain TPR_1 PF00515.28 AIN97705.1 - 3.4e-14 52.0 15.9 0.0011 18.7 0.0 6.1 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_2 PF07719.17 AIN97705.1 - 9.5e-11 41.0 24.2 0.0022 18.0 0.3 7.4 8 0 0 8 8 7 4 Tetratricopeptide repeat TPR_8 PF13181.6 AIN97705.1 - 2.4e-07 30.4 11.6 0.06 13.6 0.1 6.7 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_17 PF13431.6 AIN97705.1 - 9.3e-05 22.5 0.4 22 5.7 0.0 5.4 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_16 PF13432.6 AIN97705.1 - 0.0024 18.5 11.5 5.4 7.8 0.2 5.5 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_12 PF13424.6 AIN97705.1 - 0.0026 18.0 13.5 0.004 17.4 0.5 5.0 3 2 4 7 7 7 2 Tetratricopeptide repeat Rapsyn_N PF10579.9 AIN97705.1 - 0.0032 17.5 0.3 1.4 9.0 0.0 3.1 2 1 1 3 3 3 1 Rapsyn N-terminal myristoylation and linker region TPR_11 PF13414.6 AIN97705.1 - 0.035 13.8 0.5 12 5.7 0.3 4.1 4 0 0 4 4 4 0 TPR repeat TPR_6 PF13174.6 AIN97705.1 - 0.055 14.1 8.8 14 6.6 0.1 5.7 5 0 0 5 5 5 0 Tetratricopeptide repeat ANAPC3 PF12895.7 AIN97705.1 - 0.097 12.9 13.4 0.39 11.0 0.4 4.5 5 0 0 5 5 5 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.6 AIN97705.1 - 0.48 10.6 11.7 3 8.1 0.1 5.6 5 1 1 6 6 6 0 Tetratricopeptide repeat TPR_9 PF13371.6 AIN97705.1 - 1.6 8.9 6.7 1.5 9.0 0.7 3.6 3 1 1 4 4 4 0 Tetratricopeptide repeat Sec7 PF01369.20 AIN97707.1 - 3.2e-47 160.6 0.0 6.9e-47 159.5 0.0 1.5 2 0 0 2 2 2 1 Sec7 domain Sec7_N PF12783.7 AIN97707.1 - 7.9e-06 25.9 0.0 3.3e-05 23.8 0.0 2.1 2 0 0 2 2 2 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DLIC PF05783.11 AIN97707.1 - 0.21 10.4 0.1 0.45 9.3 0.1 1.4 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) GTP_EFTU PF00009.27 AIN97708.1 - 2.1e-07 30.7 0.0 8.3e-07 28.7 0.0 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_29 PF13555.6 AIN97708.1 - 0.011 15.5 0.5 0.27 11.0 0.3 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain ATP_bind_1 PF03029.17 AIN97708.1 - 0.011 15.5 2.7 0.36 10.6 0.5 2.2 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein RsgA_GTPase PF03193.16 AIN97708.1 - 0.025 14.5 0.5 1.5 8.7 0.1 2.3 2 0 0 2 2 2 0 RsgA GTPase GTP_EFTU_D2 PF03144.25 AIN97708.1 - 0.13 12.7 0.4 0.4 11.1 0.1 2.0 2 0 0 2 2 2 0 Elongation factor Tu domain 2 ABC_tran PF00005.27 AIN97708.1 - 0.14 12.7 0.1 0.44 11.1 0.0 1.8 2 0 0 2 2 2 0 ABC transporter Ribosomal_L35Ae PF01247.18 AIN97709.1 - 3e-32 110.6 0.5 5e-32 109.9 0.5 1.3 1 0 0 1 1 1 1 Ribosomal protein L35Ae RimM PF01782.18 AIN97709.1 - 3e-05 24.2 0.2 0.076 13.2 0.0 2.4 2 1 0 2 2 2 2 RimM N-terminal domain HlyIII PF03006.20 AIN97710.1 - 0.0048 16.6 0.5 0.0057 16.4 0.5 1.0 1 0 0 1 1 1 1 Haemolysin-III related MFS_MOT1 PF16983.5 AIN97711.1 - 0.04 14.3 1.9 0.11 12.8 0.9 2.1 1 1 1 2 2 2 0 Molybdate transporter of MFS superfamily TarH PF02203.15 AIN97711.1 - 0.045 13.7 0.1 0.07 13.1 0.1 1.3 1 0 0 1 1 1 0 Tar ligand binding domain homologue Trp_oprn_chp PF09534.10 AIN97711.1 - 0.081 12.7 4.3 0.17 11.7 4.3 1.6 1 0 0 1 1 1 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) ATG16 PF08614.11 AIN97713.1 - 0.0041 17.4 25.9 0.0041 17.4 25.9 8.9 3 2 5 9 9 9 2 Autophagy protein 16 (ATG16) CENP-F_leu_zip PF10473.9 AIN97713.1 - 0.0077 16.3 18.3 0.0077 16.3 18.3 7.8 3 2 3 7 7 7 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 LRR_6 PF13516.6 AIN97714.1 - 5.7e-08 32.2 1.4 0.09 12.9 0.0 4.3 5 0 0 5 5 5 3 Leucine Rich repeat PLRV_ORF5 PF01690.17 AIN97714.1 - 0.11 11.2 2.5 0.15 10.8 2.5 1.1 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein ANAPC4_WD40 PF12894.7 AIN97715.1 - 0.00034 20.9 0.0 1.9 8.8 0.0 3.6 3 0 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 AIN97715.1 - 0.055 14.3 4.7 6.6 7.8 0.1 3.9 3 0 0 3 3 3 0 WD domain, G-beta repeat PP2C PF00481.21 AIN97716.1 - 5.2e-54 183.6 0.0 7.4e-54 183.1 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 AIN97716.1 - 6.8e-05 22.6 0.0 0.00014 21.5 0.0 1.6 1 1 0 1 1 1 1 Protein phosphatase 2C PP2C PF00481.21 AIN97717.1 - 1.1e-54 185.8 0.0 1.4e-54 185.4 0.0 1.1 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 AIN97717.1 - 0.051 13.2 0.0 0.094 12.3 0.0 1.5 1 1 0 1 1 1 0 Protein phosphatase 2C Sec7 PF01369.20 AIN97718.1 - 4.9e-50 169.8 0.0 3e-49 167.2 0.0 2.1 2 0 0 2 2 2 1 Sec7 domain DUF1981 PF09324.10 AIN97718.1 - 9.7e-19 67.0 0.1 2.7e-18 65.6 0.1 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF1981) Sec7_N PF12783.7 AIN97718.1 - 1.9e-18 66.8 1.1 7.2e-18 65.0 0.3 2.4 2 0 0 2 2 2 1 Guanine nucleotide exchange factor in Golgi transport N-terminal FliJ PF02050.16 AIN97719.1 - 0.00048 20.3 4.2 0.00048 20.3 4.2 7.9 3 1 5 8 8 8 1 Flagellar FliJ protein DUF948 PF06103.11 AIN97719.1 - 0.0007 19.8 23.6 0.64 10.3 0.1 7.5 6 2 1 7 7 7 2 Bacterial protein of unknown function (DUF948) CENP-F_leu_zip PF10473.9 AIN97719.1 - 0.0045 17.0 5.1 0.0045 17.0 5.1 7.1 3 1 4 7 7 7 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 HAUS-augmin3 PF14932.6 AIN97719.1 - 0.006 16.2 12.7 0.006 16.2 12.7 6.5 4 1 2 6 6 6 1 HAUS augmin-like complex subunit 3 Mod_r PF07200.13 AIN97719.1 - 0.26 11.4 81.8 0.23 11.5 4.2 7.0 2 2 6 8 8 8 0 Modifier of rudimentary (Mod(r)) protein APG6_N PF17675.1 AIN97719.1 - 2.3 8.8 132.1 0.81 10.2 12.7 8.3 4 1 4 8 8 8 0 Apg6 coiled-coil region Fez1 PF06818.15 AIN97719.1 - 3.8 7.9 97.6 0.037 14.5 16.2 7.0 1 1 2 4 4 4 0 Fez1 Streptin-Immun PF11083.8 AIN97719.1 - 7.3 7.1 18.4 2.2 8.7 4.0 5.8 4 2 0 4 4 4 0 Lantibiotic streptin immunity protein Rootletin PF15035.6 AIN97720.1 - 0.0018 18.3 3.7 0.0018 18.3 3.7 3.8 3 1 0 3 3 3 1 Ciliary rootlet component, centrosome cohesion DASH_Dad1 PF08649.10 AIN97720.1 - 3.1 8.1 4.9 4.3 7.6 0.3 3.1 3 0 0 3 3 3 0 DASH complex subunit Dad1 Filament PF00038.21 AIN97720.1 - 8.4 5.9 52.7 13 5.3 12.2 4.0 2 2 0 2 2 2 0 Intermediate filament protein DUF5446 PF17522.2 AIN97720.1 - 9.6 6.5 12.3 0.16 12.2 2.5 3.2 3 0 0 3 3 3 0 Family of unknown function (DUF5446) Lebercilin PF15619.6 AIN97721.1 - 2.8e-05 23.9 16.1 2.8e-05 23.9 16.1 7.1 5 1 2 7 7 7 1 Ciliary protein causing Leber congenital amaurosis disease C2 PF00168.30 AIN97721.1 - 0.00075 19.7 0.0 0.0019 18.5 0.0 1.7 1 0 0 1 1 1 1 C2 domain HOOK PF05622.12 AIN97721.1 - 0.0021 16.3 10.3 0.0021 16.3 10.3 4.7 2 1 1 4 4 4 1 HOOK protein Fez1 PF06818.15 AIN97721.1 - 0.0024 18.3 25.4 0.0024 18.3 25.4 5.1 3 2 2 5 5 5 2 Fez1 TMF_DNA_bd PF12329.8 AIN97721.1 - 0.012 15.6 8.0 0.012 15.6 8.0 10.8 9 3 1 10 10 10 0 TATA element modulatory factor 1 DNA binding Shugoshin_N PF07558.11 AIN97721.1 - 0.013 15.4 31.4 0.045 13.6 0.2 8.9 8 1 1 9 9 9 0 Shugoshin N-terminal coiled-coil region Pox_A_type_inc PF04508.12 AIN97721.1 - 1.7 8.6 40.8 0.43 10.5 0.5 9.1 10 0 0 10 10 10 0 Viral A-type inclusion protein repeat Surfac_D-trimer PF09006.11 AIN97721.1 - 4 7.4 5.8 3.7 7.5 0.2 3.5 4 0 0 4 4 4 0 Lung surfactant protein D coiled-coil trimerisation IFT57 PF10498.9 AIN97722.1 - 0.00019 20.6 0.9 0.00019 20.6 0.9 2.1 3 0 0 3 3 3 1 Intra-flagellar transport protein 57 DUF5344 PF17279.2 AIN97722.1 - 0.012 16.1 1.5 0.1 13.2 0.9 2.6 2 0 0 2 2 2 0 Family of unknown function (DUF5344) DUF4726 PF15855.5 AIN97722.1 - 0.032 14.4 0.1 0.47 10.7 0.0 2.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4726) OmpH PF03938.14 AIN97722.1 - 0.37 11.1 10.9 0.19 12.1 6.2 2.3 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) RecG_N PF17190.4 AIN97722.1 - 1.1 10.0 5.3 0.76 10.5 0.4 2.6 2 0 0 2 2 2 0 RecG N-terminal helical domain Talin_middle PF09141.10 AIN97723.1 - 0.026 14.5 0.6 0.045 13.8 0.6 1.4 1 0 0 1 1 1 0 Talin, middle domain Cauli_AT PF03233.13 AIN97723.1 - 0.046 13.6 0.7 0.1 12.5 0.7 1.5 1 0 0 1 1 1 0 Aphid transmission protein DUF2353 PF09789.9 AIN97723.1 - 0.068 12.5 13.0 0.1 11.9 13.0 1.2 1 0 0 1 1 1 0 Uncharacterized coiled-coil protein (DUF2353) GEMIN8 PF15348.6 AIN97723.1 - 0.14 12.5 8.5 0.21 11.8 8.5 1.3 1 0 0 1 1 1 0 Gemini of Cajal bodies-associated protein 8 DUF870 PF05912.11 AIN97723.1 - 0.15 12.1 3.9 1.1 9.3 0.6 2.5 1 1 1 2 2 2 0 Caenorhabditis elegans protein of unknown function (DUF870) CENP-F_leu_zip PF10473.9 AIN97723.1 - 0.3 11.1 16.0 0.52 10.3 16.0 1.4 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 FapA PF03961.13 AIN97723.1 - 3.7 6.1 7.2 11 4.5 6.4 1.7 1 1 1 2 2 2 0 Flagellar Assembly Protein A FUSC PF04632.12 AIN97723.1 - 9.4 4.6 8.5 13 4.1 8.5 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family Marek_SORF3 PF07153.11 AIN97724.1 - 0.02 14.2 0.8 0.034 13.5 0.5 1.5 1 1 0 1 1 1 0 Marek's disease-like virus SORF3 protein Corona_S2 PF01601.16 AIN97725.1 - 0.18 10.2 6.1 0.035 12.6 1.6 2.0 1 1 2 3 3 3 0 Coronavirus S2 glycoprotein DUF3800 PF12686.7 AIN97725.1 - 3.9 8.1 6.2 1.2e+02 3.3 5.7 2.9 1 1 0 1 1 1 0 Protein of unknown function (DUF3800) Alba PF01918.21 AIN97726.1 - 5.2e-17 61.4 0.4 8.2e-17 60.8 0.4 1.3 1 0 0 1 1 1 1 Alba Rpp20 PF12328.8 AIN97726.1 - 0.0016 18.4 0.3 0.0035 17.3 0.3 1.6 1 1 0 1 1 1 1 Rpp20 subunit of nuclear RNase MRP and P RhlB PF12300.8 AIN97726.1 - 1.7 8.7 16.2 0.21 11.7 11.2 1.9 2 0 0 2 2 2 0 ATP-dependent RNA helicase RhlB Adap_comp_sub PF00928.21 AIN97727.1 - 3.3e-56 190.6 0.0 4.1e-56 190.3 0.0 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 AIN97727.1 - 0.00025 21.0 0.2 0.00046 20.1 0.2 1.3 1 0 0 1 1 1 1 Clathrin adaptor complex small chain ACBP PF00887.19 AIN97728.1 - 8.2e-17 61.2 1.9 9.3e-17 61.0 1.9 1.0 1 0 0 1 1 1 1 Acyl CoA binding protein TIP49 PF06068.13 AIN97729.1 - 5.1e-158 525.9 1.5 1.2e-157 524.6 0.6 1.8 2 0 0 2 2 2 1 TIP49 P-loop domain TIP49_C PF17856.1 AIN97729.1 - 4.6e-25 87.5 1.8 6.1e-25 87.1 0.7 1.9 2 0 0 2 2 1 1 TIP49 AAA-lid domain AAA PF00004.29 AIN97729.1 - 1.3e-08 35.3 2.0 8e-06 26.3 0.1 3.1 3 1 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 AIN97729.1 - 1.9e-07 31.0 0.6 0.00017 21.3 0.1 2.9 3 0 0 3 3 3 2 Holliday junction DNA helicase RuvB P-loop domain DnaB_C PF03796.15 AIN97729.1 - 1e-05 25.0 0.2 2.1e-05 24.0 0.2 1.5 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain AAA_16 PF13191.6 AIN97729.1 - 1.5e-05 25.5 0.1 8.6e-05 23.0 0.1 2.2 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 AIN97729.1 - 2.2e-05 24.8 0.2 0.16 12.3 0.0 2.8 1 1 0 2 2 2 2 AAA domain AAA_5 PF07728.14 AIN97729.1 - 4.4e-05 23.5 0.2 0.0099 15.9 0.0 3.0 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 AIN97729.1 - 5.8e-05 22.6 1.3 0.0011 18.4 0.6 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_19 PF13245.6 AIN97729.1 - 0.00011 22.6 4.1 0.00057 20.2 1.5 2.6 2 1 0 2 2 1 1 AAA domain Zeta_toxin PF06414.12 AIN97729.1 - 0.0032 16.8 0.3 0.0077 15.5 0.3 1.6 1 0 0 1 1 1 1 Zeta toxin Sigma54_activat PF00158.26 AIN97729.1 - 0.0033 17.2 0.0 1.4 8.6 0.1 2.6 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_17 PF13207.6 AIN97729.1 - 0.0037 17.7 0.1 0.028 14.8 0.0 2.5 2 1 0 2 2 2 1 AAA domain CPT PF07931.12 AIN97729.1 - 0.007 16.2 0.4 0.028 14.3 0.1 2.3 2 1 0 2 2 2 1 Chloramphenicol phosphotransferase-like protein ATPase PF06745.13 AIN97729.1 - 0.0083 15.5 0.2 0.02 14.3 0.2 1.7 1 0 0 1 1 1 1 KaiC AAA_28 PF13521.6 AIN97729.1 - 0.016 15.5 0.1 0.034 14.4 0.1 1.6 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 AIN97729.1 - 0.027 14.2 0.2 0.089 12.5 0.2 1.8 1 0 0 1 1 1 0 IstB-like ATP binding protein NACHT PF05729.12 AIN97729.1 - 0.027 14.4 0.0 0.088 12.7 0.0 1.8 2 0 0 2 2 2 0 NACHT domain AAA_25 PF13481.6 AIN97729.1 - 0.029 13.9 0.1 0.092 12.3 0.1 1.8 1 0 0 1 1 1 0 AAA domain DUF2075 PF09848.9 AIN97729.1 - 0.042 13.1 0.0 0.075 12.3 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) GATase PF00117.28 AIN97729.1 - 0.049 13.4 0.1 0.83 9.4 0.0 2.2 2 0 0 2 2 2 0 Glutamine amidotransferase class-I Sigma54_activ_2 PF14532.6 AIN97729.1 - 0.049 13.7 0.0 0.61 10.2 0.0 2.5 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_7 PF12775.7 AIN97729.1 - 0.067 12.7 0.4 0.25 10.8 0.1 2.1 2 0 0 2 2 2 0 P-loop containing dynein motor region ABC_tran PF00005.27 AIN97729.1 - 0.081 13.4 0.2 0.18 12.3 0.2 1.6 1 0 0 1 1 1 0 ABC transporter AAA_29 PF13555.6 AIN97729.1 - 0.1 12.4 0.2 0.57 10.0 0.1 2.1 2 0 0 2 2 2 0 P-loop containing region of AAA domain TsaE PF02367.17 AIN97729.1 - 0.1 12.6 0.1 0.31 11.1 0.1 1.8 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE TFIID-31kDa PF02291.15 AIN97729.1 - 0.1 12.7 0.0 0.2 11.8 0.0 1.4 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit SUV3_C PF12513.8 AIN97730.1 - 7.2e-09 35.5 0.1 1.8e-08 34.2 0.1 1.7 1 0 0 1 1 1 1 Mitochondrial degradasome RNA helicase subunit C terminal Suv3_C_1 PF18147.1 AIN97730.1 - 2.5e-08 33.7 2.1 8e-08 32.0 0.4 2.7 3 0 0 3 3 3 1 Suv3 C-terminal domain 1 Helicase_C PF00271.31 AIN97730.1 - 0.00031 21.0 0.0 0.0019 18.5 0.0 2.1 1 1 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 AIN97730.1 - 0.026 14.3 0.0 0.17 11.7 0.0 2.2 1 1 0 1 1 1 0 DEAD/DEAH box helicase Kinesin PF00225.23 AIN97730.1 - 0.15 10.9 0.0 0.24 10.3 0.0 1.2 1 0 0 1 1 1 0 Kinesin motor domain PhoLip_ATPase_C PF16212.5 AIN97731.1 - 1.9e-43 149.0 22.8 1.9e-43 149.0 22.8 2.3 2 0 0 2 2 2 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 AIN97731.1 - 1.2e-23 82.5 0.3 3.1e-23 81.2 0.3 1.7 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Hydrolase PF00702.26 AIN97731.1 - 1.3e-12 48.5 1.1 1.5e-06 28.6 1.9 3.2 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 AIN97731.1 - 6.8e-09 35.7 0.0 1.9e-07 31.1 0.0 2.4 2 0 0 2 2 2 1 Cation transport ATPase (P-type) E1-E2_ATPase PF00122.20 AIN97731.1 - 0.00048 19.7 4.4 0.0011 18.6 0.0 2.9 3 0 0 3 3 3 1 E1-E2 ATPase Hydrolase_3 PF08282.12 AIN97731.1 - 0.0017 18.2 0.0 0.0033 17.2 0.0 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 AIN97731.1 - 0.0071 16.8 0.1 6.7 7.1 0.1 2.8 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase HTH_40 PF14493.6 AIN97731.1 - 0.058 13.9 0.1 0.28 11.7 0.1 2.0 2 0 0 2 2 2 0 Helix-turn-helix domain Cytochrome-c551 PF10643.9 AIN97732.1 - 0.014 15.0 1.4 0.015 14.8 1.4 1.1 1 0 0 1 1 1 0 Photosystem P840 reaction-centre cytochrome c-551 DUF21 PF01595.20 AIN97733.1 - 2.5e-33 115.3 0.3 5.1e-33 114.2 0.3 1.4 1 0 0 1 1 1 1 Cyclin M transmembrane N-terminal domain CBS PF00571.28 AIN97733.1 - 1.3e-06 28.8 0.1 0.0054 17.1 0.0 2.6 2 0 0 2 2 2 2 CBS domain cNMP_binding PF00027.29 AIN97733.1 - 0.0053 16.8 0.0 0.012 15.6 0.0 1.6 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain MHYT PF03707.16 AIN97733.1 - 2.3 8.4 6.7 7.1 6.9 0.6 2.6 2 0 0 2 2 2 0 Bacterial signalling protein N terminal repeat Vps52 PF04129.12 AIN97734.1 - 6.1e-14 51.6 5.5 4.1e-12 45.6 4.6 2.2 2 0 0 2 2 2 2 Vps52 / Sac2 family FAD_binding_1 PF00667.20 AIN97735.1 - 8.8e-32 110.5 0.0 1.3e-31 110.0 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.25 AIN97735.1 - 8.1e-24 84.5 0.0 1.5e-23 83.6 0.0 1.5 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.21 AIN97735.1 - 1.4e-14 54.6 0.0 2.9e-14 53.6 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain WD40 PF00400.32 AIN97736.1 - 3.5e-15 56.1 3.5 0.00096 19.9 0.3 6.2 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 AIN97736.1 - 9.7e-06 25.8 0.1 0.0066 16.7 0.1 2.9 2 0 0 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain DUF2478 PF10649.9 AIN97737.1 - 0.021 14.5 0.1 0.044 13.4 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2478) RRM_1 PF00076.22 AIN97738.1 - 1.3e-11 44.1 0.0 2.5e-11 43.2 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) eIF3g PF12353.8 AIN97738.1 - 0.0027 18.1 0.3 0.0061 17.0 0.1 1.6 1 1 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit G Orthopox_C10L PF07020.11 AIN97738.1 - 0.11 13.3 0.1 0.18 12.5 0.1 1.4 1 0 0 1 1 1 0 Orthopoxvirus C10L protein PMP1_2 PF08114.11 AIN97740.1 - 0.5 10.1 2.2 11 5.9 0.0 2.7 2 0 0 2 2 2 0 ATPase proteolipid family Methyltransf_11 PF08241.12 AIN97742.1 - 1e-08 35.7 0.0 0.0073 16.9 0.0 2.4 2 0 0 2 2 2 2 Methyltransferase domain WBS_methylT PF12589.8 AIN97742.1 - 1.5e-08 35.3 14.7 4e-08 33.9 14.7 1.8 1 1 0 1 1 1 1 Methyltransferase involved in Williams-Beuren syndrome Methyltransf_25 PF13649.6 AIN97742.1 - 4.7e-07 30.4 0.0 0.0018 18.9 0.0 2.5 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_12 PF08242.12 AIN97742.1 - 0.0012 19.5 0.0 0.19 12.5 0.0 2.7 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_31 PF13847.6 AIN97742.1 - 0.0018 18.1 0.0 0.075 12.8 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 AIN97742.1 - 0.0026 17.6 0.0 0.0036 17.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Transket_pyr PF02779.24 AIN97742.1 - 0.11 12.2 0.1 7.6 6.2 0.1 2.4 2 0 0 2 2 2 0 Transketolase, pyrimidine binding domain CDC45 PF02724.14 AIN97742.1 - 5.8 5.1 11.3 11 4.1 7.7 2.0 2 0 0 2 2 2 0 CDC45-like protein Metallophos PF00149.28 AIN97745.1 - 2.6e-16 60.7 0.0 1.8e-12 48.2 0.0 3.3 2 1 0 2 2 2 2 Calcineurin-like phosphoesterase DUF3220 PF11516.8 AIN97745.1 - 0.1 12.8 0.0 0.25 11.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3120) Ribosomal_S19e PF01090.19 AIN97746.1 - 2.7e-43 147.0 0.0 3.1e-43 146.7 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S19e Mrr_N PF14338.6 AIN97746.1 - 0.0086 16.2 0.0 0.015 15.4 0.0 1.4 1 0 0 1 1 1 1 Mrr N-terminal domain SRP68 PF16969.5 AIN97747.1 - 1.6e-52 179.3 13.1 6.4e-43 147.6 11.9 3.0 1 1 1 2 2 2 2 RNA-binding signal recognition particle 68 TPR_2 PF07719.17 AIN97747.1 - 0.029 14.5 3.0 0.082 13.1 0.2 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_21 PF09976.9 AIN97747.1 - 1.2 8.8 5.7 1 9.0 0.2 2.7 3 0 0 3 3 3 0 Tetratricopeptide repeat-like domain TPR_12 PF13424.6 AIN97747.1 - 1.7 9.0 5.5 0.31 11.4 0.3 2.5 3 0 0 3 3 3 0 Tetratricopeptide repeat Amastin PF07344.11 AIN97748.1 - 1.8e-53 180.6 11.6 2.3e-53 180.2 11.6 1.1 1 0 0 1 1 1 1 Amastin surface glycoprotein Peptidase_M14 PF00246.24 AIN97749.1 - 2.7e-19 70.1 0.0 9.3e-19 68.3 0.0 1.9 1 1 0 1 1 1 1 Zinc carboxypeptidase Pepdidase_M14_N PF18027.1 AIN97749.1 - 2.3e-07 31.1 0.1 5e-07 30.0 0.1 1.5 1 0 0 1 1 1 1 Cytosolic carboxypeptidase N-terminal domain AstE_AspA PF04952.14 AIN97749.1 - 0.00012 21.3 0.0 0.00024 20.3 0.0 1.6 1 1 0 1 1 1 1 Succinylglutamate desuccinylase / Aspartoacylase family cNMP_binding PF00027.29 AIN97750.1 - 2e-22 79.0 0.1 2.8e-11 43.3 0.0 2.6 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain Cupin_2 PF07883.11 AIN97750.1 - 0.088 12.5 0.0 0.71 9.6 0.0 2.2 2 0 0 2 2 2 0 Cupin domain HlyD_D4 PF16572.5 AIN97750.1 - 0.19 11.6 0.4 1 9.3 0.1 2.4 3 0 0 3 3 3 0 Long alpha hairpin domain of cation efflux system protein, CusB GTP_EFTU PF00009.27 AIN97750.1 - 0.34 10.4 2.3 0.29 10.7 0.5 1.8 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain Urm1 PF09138.11 AIN97751.1 - 1.9e-24 85.8 0.0 2.2e-24 85.6 0.0 1.0 1 0 0 1 1 1 1 Urm1 (Ubiquitin related modifier) ThiS PF02597.20 AIN97751.1 - 1.8e-06 28.5 0.1 2.1e-06 28.3 0.1 1.2 1 0 0 1 1 1 1 ThiS family TGS PF02824.21 AIN97751.1 - 0.1 12.7 0.4 0.19 11.8 0.1 1.6 2 0 0 2 2 2 0 TGS domain GTP_EFTU PF00009.27 AIN97752.1 - 7.7e-28 97.4 0.0 1.2e-27 96.7 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 AIN97752.1 - 2.4e-07 30.8 0.0 5.8e-07 29.6 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D2 PF03144.25 AIN97752.1 - 1.6e-05 25.2 0.3 4.1e-05 23.9 0.3 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 SRPRB PF09439.10 AIN97752.1 - 0.00062 19.2 0.4 0.012 15.0 0.1 2.5 2 1 0 2 2 2 1 Signal recognition particle receptor beta subunit PduV-EutP PF10662.9 AIN97752.1 - 0.0048 16.6 0.1 3 7.6 0.0 2.4 2 0 0 2 2 2 2 Ethanolamine utilisation - propanediol utilisation cobW PF02492.19 AIN97752.1 - 0.0048 16.5 4.6 0.011 15.3 0.5 3.0 2 1 1 3 3 3 1 CobW/HypB/UreG, nucleotide-binding domain ATP_bind_1 PF03029.17 AIN97752.1 - 0.03 14.1 0.1 0.4 10.4 0.0 2.6 2 1 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_16 PF13191.6 AIN97752.1 - 0.035 14.5 0.1 0.12 12.8 0.1 1.9 1 0 0 1 1 1 0 AAA ATPase domain Hexapep PF00132.24 AIN97753.1 - 1.1e-10 40.7 11.1 8.6e-07 28.5 0.9 2.8 2 1 0 2 2 2 2 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 AIN97753.1 - 0.006 16.3 15.5 0.92 9.3 0.2 3.8 3 2 0 4 4 4 3 Hexapeptide repeat of succinyl-transferase SAS4 PF15460.6 AIN97754.1 - 0.061 13.4 0.0 0.084 13.0 0.0 1.2 1 0 0 1 1 1 0 Something about silencing, SAS, complex subunit 4 Ribosomal_L3 PF00297.22 AIN97755.1 - 3.4e-148 493.6 9.1 3.9e-148 493.3 9.1 1.0 1 0 0 1 1 1 1 Ribosomal protein L3 Ribosomal_L3 PF00297.22 AIN97756.1 - 3.4e-148 493.6 9.1 3.9e-148 493.3 9.1 1.0 1 0 0 1 1 1 1 Ribosomal protein L3 Patatin PF01734.22 AIN97757.1 - 2.3e-08 34.4 2.0 1.6e-07 31.8 2.0 2.0 1 1 0 1 1 1 1 Patatin-like phospholipase DUF1616 PF07760.11 AIN97758.1 - 0.087 12.2 0.0 0.095 12.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1616) Phage_holin_2_4 PF16082.5 AIN97758.1 - 0.1 12.4 0.0 0.12 12.1 0.0 1.2 1 0 0 1 1 1 0 Bacteriophage holin family, superfamily II-like Thioredoxin PF00085.20 AIN97759.1 - 0.0058 16.6 0.0 0.0097 15.9 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin EF-hand_8 PF13833.6 AIN97761.1 - 1.7e-10 40.6 0.1 1e-07 31.7 0.0 2.9 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_7 PF13499.6 AIN97761.1 - 1.1e-09 38.5 0.0 0.0024 18.3 0.0 4.2 4 0 0 4 4 4 3 EF-hand domain pair EF-hand_6 PF13405.6 AIN97761.1 - 1.2e-09 37.3 0.1 0.00037 20.2 0.0 6.0 6 1 1 7 7 7 2 EF-hand domain EF-hand_5 PF13202.6 AIN97761.1 - 1.3e-09 37.1 2.4 0.011 15.1 0.0 5.2 5 0 0 5 5 5 2 EF hand EF-hand_1 PF00036.32 AIN97761.1 - 4e-09 35.4 0.0 0.00011 21.4 0.0 4.5 6 0 0 6 6 6 2 EF hand Spc7 PF08317.11 AIN97763.1 - 0.0009 18.2 11.2 0.0014 17.6 11.2 1.2 1 0 0 1 1 1 1 Spc7 kinetochore protein DUF4618 PF15397.6 AIN97763.1 - 0.2 11.0 13.1 1.3 8.3 13.2 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4618) CHDCT2 PF08074.11 AIN97763.1 - 0.37 11.0 5.9 3.7 7.7 6.1 1.9 1 1 1 2 2 2 0 CHDCT2 (NUC038) domain ADIP PF11559.8 AIN97763.1 - 7.4 6.6 17.1 27 4.8 17.1 1.9 1 1 0 1 1 1 0 Afadin- and alpha -actinin-Binding SlyX PF04102.12 AIN97763.1 - 8.4 7.1 11.0 3.6 8.3 2.7 3.3 1 1 2 3 3 3 0 SlyX DivIC PF04977.15 AIN97763.1 - 9.6 6.1 16.2 2.2 8.1 4.9 2.8 1 1 1 2 2 2 0 Septum formation initiator NDK PF00334.19 AIN97764.1 - 1.6e-14 54.1 0.0 4.6e-13 49.4 0.0 2.3 2 0 0 2 2 2 1 Nucleoside diphosphate kinase DUF1126 PF06565.12 AIN97764.1 - 0.0023 17.7 0.0 0.0058 16.4 0.0 1.6 1 1 0 1 1 1 1 DUF1126 PH-like domain ATF7IP_BD PF16788.5 AIN97765.1 - 0.043 13.9 1.4 0.071 13.2 1.4 1.2 1 0 0 1 1 1 0 ATF-interacting protein binding domain LRR_6 PF13516.6 AIN97765.1 - 0.087 12.9 0.2 0.26 11.4 0.0 1.9 2 0 0 2 2 2 0 Leucine Rich repeat GEMIN8 PF15348.6 AIN97765.1 - 0.09 13.1 2.8 0.13 12.6 2.8 1.1 1 0 0 1 1 1 0 Gemini of Cajal bodies-associated protein 8 Rhodanese PF00581.20 AIN97767.1 - 8.7e-12 45.5 0.0 1.6e-11 44.7 0.0 1.4 1 0 0 1 1 1 1 Rhodanese-like domain Aldolase PF01081.19 AIN97767.1 - 0.15 11.4 0.0 4.1 6.8 0.0 2.1 2 0 0 2 2 2 0 KDPG and KHG aldolase Pkinase PF00069.25 AIN97768.1 - 2.6e-19 69.6 0.0 1.8e-18 66.9 0.0 1.9 2 0 0 2 2 2 1 Protein kinase domain Pkinase_fungal PF17667.1 AIN97768.1 - 0.008 15.0 0.0 0.012 14.5 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 AIN97768.1 - 0.064 12.6 0.0 0.11 11.9 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 AIN97768.1 - 0.23 11.4 2.3 0.94 9.3 0.0 2.9 3 1 1 4 4 4 0 Phosphotransferase enzyme family RMP PF14996.6 AIN97769.1 - 8.6e-10 39.0 8.5 5.1e-08 33.3 5.1 3.3 2 1 0 2 2 2 1 Retinal Maintenance Beta_helix PF13229.6 AIN97770.1 - 0.0059 16.5 0.0 0.062 13.2 0.0 2.1 2 0 0 2 2 2 1 Right handed beta helix region IucA_IucC PF04183.12 AIN97770.1 - 0.097 12.2 0.3 0.29 10.7 0.2 1.8 2 0 0 2 2 2 0 IucA / IucC family Adeno_E1B_55K PF01696.17 AIN97770.1 - 0.21 10.2 3.2 0.086 11.5 0.6 1.5 2 0 0 2 2 2 0 Adenovirus EB1 55K protein / large t-antigen Cyt-b5 PF00173.28 AIN97771.1 - 1.1e-06 28.6 0.1 2.1e-06 27.8 0.1 1.5 1 1 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Mito_carr PF00153.27 AIN97772.1 - 9.9e-46 153.6 5.2 1.5e-22 79.3 0.2 3.4 3 0 0 3 3 3 3 Mitochondrial carrier protein GrlR PF16518.5 AIN97773.1 - 0.021 14.8 0.0 0.044 13.8 0.0 1.4 1 0 0 1 1 1 0 T3SS negative regulator,GrlR SWIM PF04434.17 AIN97773.1 - 2.9 7.6 8.2 0.7 9.6 3.0 2.3 2 0 0 2 2 2 0 SWIM zinc finger DNA_pol_A_exo1 PF01612.20 AIN97774.1 - 7.2e-37 126.8 0.4 1.3e-36 125.9 0.4 1.5 1 0 0 1 1 1 1 3'-5' exonuclease PMC2NT PF08066.12 AIN97774.1 - 2.6e-20 72.9 0.3 1.2e-19 70.7 0.0 2.4 3 0 0 3 3 3 1 PMC2NT (NUC016) domain HRDC PF00570.23 AIN97774.1 - 3.6e-09 36.5 0.0 8.3e-09 35.3 0.0 1.7 1 0 0 1 1 1 1 HRDC domain 2_5_RNA_ligase2 PF13563.6 AIN97774.1 - 0.062 13.2 1.3 0.26 11.2 0.3 2.5 3 0 0 3 3 3 0 2'-5' RNA ligase superfamily Pup PF05639.11 AIN97774.1 - 5.8 7.9 5.9 1.2 10.1 0.1 2.6 2 0 0 2 2 2 0 Pup-like protein PIP5K PF01504.18 AIN97775.1 - 3.6e-68 229.8 0.0 1.2e-67 228.0 0.0 1.8 1 1 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase Sec15 PF04091.12 AIN97775.1 - 0.11 11.9 0.2 0.21 11.0 0.2 1.4 1 0 0 1 1 1 0 Exocyst complex subunit Sec15-like AAA_33 PF13671.6 AIN97777.1 - 2e-11 44.2 0.0 3.1e-11 43.6 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 AIN97777.1 - 0.00029 21.1 0.1 0.00083 19.6 0.1 1.7 1 1 0 1 1 1 1 AAA domain KTI12 PF08433.10 AIN97777.1 - 0.0009 18.8 0.1 0.0012 18.3 0.1 1.2 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_14 PF13173.6 AIN97777.1 - 0.0015 18.6 0.0 0.0023 18.0 0.0 1.2 1 0 0 1 1 1 1 AAA domain BORCS8 PF10167.9 AIN97777.1 - 0.0024 17.8 0.1 0.0044 17.0 0.1 1.4 1 0 0 1 1 1 1 BLOC-1-related complex sub-unit 8 Zeta_toxin PF06414.12 AIN97777.1 - 0.011 15.1 0.0 0.018 14.3 0.0 1.7 1 1 0 1 1 1 0 Zeta toxin AAA_18 PF13238.6 AIN97777.1 - 0.016 15.7 0.9 0.02 15.4 0.0 1.6 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.14 AIN97777.1 - 0.055 13.5 0.0 0.12 12.4 0.0 1.6 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) TPT PF03151.16 AIN97778.1 - 1.4e-07 31.1 25.3 1.9e-07 30.7 25.3 1.2 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 AIN97778.1 - 7.2e-05 23.0 39.4 0.003 17.7 19.0 2.1 2 0 0 2 2 2 2 EamA-like transporter family Phage_holin_2_4 PF16082.5 AIN97778.1 - 0.035 13.8 0.1 0.27 11.0 0.0 2.2 2 0 0 2 2 2 0 Bacteriophage holin family, superfamily II-like WW PF00397.26 AIN97780.1 - 0.022 14.9 2.7 0.024 14.7 0.8 2.1 2 0 0 2 2 2 0 WW domain zf-CCHC PF00098.23 AIN97780.1 - 0.05 13.7 4.1 0.05 13.7 4.1 3.7 4 0 0 4 4 4 0 Zinc knuckle zinc-ribbons_6 PF07191.12 AIN97780.1 - 0.56 10.2 18.0 0.91 9.6 11.2 2.9 2 1 0 2 2 2 0 zinc-ribbons EBP50_C PF09007.11 AIN97780.1 - 1.8 9.6 12.7 2.7 9.0 4.6 2.2 2 0 0 2 2 2 0 EBP50, C-terminal DUF3239 PF11580.8 AIN97781.1 - 0.086 13.2 0.1 0.17 12.2 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3239) CesT PF05932.13 AIN97783.1 - 1.8e-11 44.2 0.5 3.9e-11 43.1 0.5 1.6 1 0 0 1 1 1 1 Tir chaperone protein (CesT) family ubiquitin PF00240.23 AIN97783.1 - 0.002 17.8 0.0 0.032 14.0 0.0 2.3 2 0 0 2 2 2 1 Ubiquitin family Rad60-SLD PF11976.8 AIN97783.1 - 0.036 13.9 0.0 0.081 12.8 0.0 1.5 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like MAD PF05557.13 AIN97783.1 - 0.068 11.5 10.9 0.096 11.0 10.9 1.1 1 0 0 1 1 1 0 Mitotic checkpoint protein Gp58 PF07902.11 AIN97783.1 - 0.095 11.0 0.8 0.16 10.2 0.8 1.3 1 0 0 1 1 1 0 gp58-like protein bZIP_1 PF00170.21 AIN97783.1 - 0.11 12.6 0.2 0.11 12.6 0.2 3.5 2 2 0 2 2 2 0 bZIP transcription factor Tho2 PF11262.8 AIN97783.1 - 1.3 8.2 2.9 1.8 7.7 2.9 1.3 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 PRKG1_interact PF15898.5 AIN97783.1 - 2.5 9.1 12.1 1.6 9.7 7.1 2.3 1 1 1 2 2 2 0 cGMP-dependent protein kinase interacting domain Spc7 PF08317.11 AIN97783.1 - 4.2 6.2 14.3 6.1 5.6 1.1 2.1 1 1 1 2 2 2 0 Spc7 kinetochore protein TFIIA PF03153.13 AIN97784.1 - 0.14 12.2 10.2 0.2 11.6 10.2 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Epimerase PF01370.21 AIN97785.1 - 1.4e-16 60.7 0.0 2.4e-16 59.9 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 AIN97785.1 - 6e-08 32.8 0.0 1.1e-07 31.9 0.0 1.5 1 0 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 AIN97785.1 - 6.4e-07 28.7 0.0 1.3e-06 27.6 0.0 1.6 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NmrA PF05368.13 AIN97785.1 - 4.7e-06 26.3 0.0 0.00034 20.2 0.0 2.3 2 0 0 2 2 2 1 NmrA-like family GDP_Man_Dehyd PF16363.5 AIN97785.1 - 1.5e-05 24.6 0.1 3.2e-05 23.5 0.0 1.6 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase GCV_H PF01597.19 AIN97787.1 - 0.00018 21.4 0.1 0.00029 20.7 0.1 1.3 1 0 0 1 1 1 1 Glycine cleavage H-protein HA2 PF04408.23 AIN97788.1 - 6.6e-16 58.5 0.5 8.7e-15 54.9 0.0 3.1 2 0 0 2 2 2 1 Helicase associated domain (HA2) Helicase_C PF00271.31 AIN97788.1 - 3.4e-12 46.7 0.2 1.1e-11 45.1 0.2 1.9 1 1 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 AIN97788.1 - 2.1e-09 37.4 0.1 4.4e-09 36.3 0.1 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase dsrm PF00035.26 AIN97788.1 - 4.8e-08 33.6 0.0 0.0017 19.0 0.0 4.3 4 0 0 4 4 4 1 Double-stranded RNA binding motif AAA_22 PF13401.6 AIN97788.1 - 0.00024 21.4 0.1 0.00076 19.8 0.1 1.8 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 AIN97788.1 - 0.0017 18.7 0.1 0.0054 17.1 0.1 1.9 1 0 0 1 1 1 1 AAA domain AAA_23 PF13476.6 AIN97788.1 - 0.052 14.0 0.5 0.19 12.2 0.4 1.9 2 1 0 2 2 2 0 AAA domain ATPase PF06745.13 AIN97788.1 - 0.12 11.7 0.0 0.23 10.7 0.0 1.4 1 0 0 1 1 1 0 KaiC AAA_14 PF13173.6 AIN97788.1 - 0.28 11.2 0.9 9.7 6.2 0.9 2.6 1 1 0 1 1 1 0 AAA domain TPP_enzyme_N PF02776.18 AIN97790.1 - 6.2e-32 110.6 0.0 1.9e-31 109.0 0.0 1.8 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.21 AIN97790.1 - 6.3e-22 78.0 0.0 1.1e-21 77.2 0.0 1.4 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.22 AIN97790.1 - 1.3e-15 57.3 0.1 3.9e-15 55.8 0.0 1.7 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain DXP_synthase_N PF13292.6 AIN97790.1 - 0.036 13.3 0.0 0.057 12.6 0.0 1.2 1 0 0 1 1 1 0 1-deoxy-D-xylulose-5-phosphate synthase XFP_N PF09364.10 AIN97790.1 - 0.054 12.3 0.0 0.089 11.6 0.0 1.2 1 0 0 1 1 1 0 XFP N-terminal domain DRMBL PF07522.14 AIN97791.1 - 3.1e-18 65.9 0.0 5.7e-18 65.1 0.0 1.4 1 0 0 1 1 1 1 DNA repair metallo-beta-lactamase DUF4379 PF14311.6 AIN97792.1 - 2e-14 53.7 0.1 3.7e-14 52.8 0.1 1.5 1 0 0 1 1 1 1 Probable Zinc-ribbon domain Prok-RING_4 PF14447.6 AIN97792.1 - 0.13 12.2 0.3 0.28 11.1 0.3 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-UBP PF02148.19 AIN97793.1 - 3e-17 62.7 5.7 1e-16 61.0 5.7 1.9 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein Med4 PF10018.9 AIN97793.1 - 0.011 15.4 1.1 0.032 13.9 1.1 1.7 1 0 0 1 1 1 0 Vitamin-D-receptor interacting Mediator subunit 4 UPF0242 PF06785.11 AIN97793.1 - 0.054 13.6 3.9 0.15 12.1 3.9 1.7 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DUF641 PF04859.12 AIN97793.1 - 2.9 8.3 7.9 0.098 13.0 1.4 1.9 3 0 0 3 3 3 0 Plant protein of unknown function (DUF641) Amastin PF07344.11 AIN97794.1 - 1.3e-54 184.3 11.0 1.5e-54 184.0 11.0 1.0 1 0 0 1 1 1 1 Amastin surface glycoprotein DUF2157 PF09925.9 AIN97794.1 - 0.014 15.2 2.0 0.3 10.9 1.5 2.2 1 1 0 1 1 1 0 Predicted membrane protein (DUF2157) DUF4293 PF14126.6 AIN97794.1 - 0.02 15.1 7.4 0.049 13.9 7.4 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4293) DUF805 PF05656.14 AIN97794.1 - 2.2 8.7 7.1 0.58 10.6 1.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF805) PelG PF16933.5 AIN97794.1 - 3 6.6 13.2 0.27 10.0 8.2 1.6 2 0 0 2 2 2 0 Putative exopolysaccharide Exporter (EPS-E) Amastin PF07344.11 AIN97795.1 - 2.8e-51 173.4 14.4 3.3e-51 173.2 14.4 1.0 1 0 0 1 1 1 1 Amastin surface glycoprotein DUF4293 PF14126.6 AIN97795.1 - 0.13 12.6 7.6 0.25 11.6 7.6 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4293) Amastin PF07344.11 AIN97796.1 - 8.7e-53 178.3 8.7 1e-52 178.1 8.7 1.1 1 0 0 1 1 1 1 Amastin surface glycoprotein SUR7 PF06687.12 AIN97796.1 - 2.1 7.9 19.7 4.7 6.8 0.6 3.1 2 1 0 3 3 3 0 SUR7/PalI family UPF0054 PF02130.17 AIN97798.1 - 1.9e-24 85.9 0.0 2.3e-24 85.6 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized protein family UPF0054 LRR_6 PF13516.6 AIN97799.1 - 0.00019 21.2 7.1 0.085 12.9 0.9 4.5 4 0 0 4 4 4 2 Leucine Rich repeat LRR_8 PF13855.6 AIN97799.1 - 2 8.2 8.6 4.7 7.0 3.2 3.1 1 1 1 2 2 2 0 Leucine rich repeat LRR_4 PF12799.7 AIN97799.1 - 2.4 8.7 9.0 4.6 7.8 1.3 3.4 3 1 0 3 3 3 0 Leucine Rich repeats (2 copies) TarS_C1 PF18674.1 AIN97800.1 - 0.078 12.9 0.1 0.096 12.6 0.1 1.1 1 0 0 1 1 1 0 TarS beta-glycosyltransferase C-terminal domain 1 p450 PF00067.22 AIN97801.1 - 6.4e-60 203.2 0.0 8.9e-60 202.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 DUF1477 PF07346.11 AIN97801.1 - 0.0028 17.9 0.1 0.0056 16.9 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1477) AAA PF00004.29 AIN97803.1 - 1.9e-34 118.9 0.0 4.5e-34 117.7 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 AIN97803.1 - 2.1e-05 25.0 0.3 7.6e-05 23.2 0.3 2.0 1 1 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.14 AIN97803.1 - 0.00027 21.0 0.0 0.0015 18.5 0.0 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 AIN97803.1 - 0.00046 20.5 0.1 0.21 11.9 0.1 3.0 1 1 2 3 3 3 1 AAA domain RuvB_N PF05496.12 AIN97803.1 - 0.0014 18.3 0.0 0.0041 16.9 0.0 1.7 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain NACHT PF05729.12 AIN97803.1 - 0.0022 17.9 0.2 2.2 8.1 0.0 2.8 1 1 1 2 2 2 2 NACHT domain AAA_33 PF13671.6 AIN97803.1 - 0.0036 17.5 0.2 0.012 15.8 0.2 2.1 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 AIN97803.1 - 0.0046 16.7 0.0 0.03 14.1 0.0 2.3 2 0 0 2 2 2 1 IstB-like ATP binding protein TIP49 PF06068.13 AIN97803.1 - 0.0053 16.0 0.0 0.013 14.8 0.0 1.6 1 1 1 2 2 2 1 TIP49 P-loop domain AAA_24 PF13479.6 AIN97803.1 - 0.0056 16.4 0.0 0.0094 15.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.6 AIN97803.1 - 0.012 16.0 0.0 0.025 15.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain Vps4_C PF09336.10 AIN97803.1 - 0.015 15.3 0.0 0.042 13.9 0.0 1.8 1 0 0 1 1 1 0 Vps4 C terminal oligomerisation domain Hydin_ADK PF17213.3 AIN97803.1 - 0.064 13.5 0.0 0.14 12.4 0.0 1.6 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain Mg_chelatase PF01078.21 AIN97803.1 - 0.083 12.3 0.0 0.28 10.5 0.0 1.9 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.22 AIN97803.1 - 0.22 12.0 0.0 1.4 9.3 0.0 2.1 2 0 0 2 2 2 0 RNA helicase Aldose_epim PF01263.20 AIN97805.1 - 7.1e-32 110.9 0.0 9.6e-32 110.5 0.0 1.2 1 0 0 1 1 1 1 Aldose 1-epimerase HECT PF00632.25 AIN97806.1 - 9.2e-09 35.2 0.0 0.0014 18.2 0.0 2.1 2 0 0 2 2 2 2 HECT-domain (ubiquitin-transferase) HECT PF00632.25 AIN97807.1 - 9.5e-07 28.6 0.1 1.6e-06 27.8 0.1 1.3 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Lactamase_B PF00753.27 AIN97808.1 - 3.5e-05 23.9 0.2 0.00013 22.0 0.2 2.1 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 AIN97808.1 - 0.0077 15.8 0.0 0.016 14.7 0.0 1.6 1 0 0 1 1 1 1 Beta-lactamase superfamily domain HAGH_C PF16123.5 AIN97808.1 - 0.12 12.9 0.0 0.29 11.7 0.0 1.6 1 0 0 1 1 1 0 Hydroxyacylglutathione hydrolase C-terminus Beta-Casp PF10996.8 AIN97809.1 - 6.8e-32 110.0 0.0 2.9e-31 108.0 0.0 2.2 2 0 0 2 2 2 1 Beta-Casp domain CPSF73-100_C PF11718.8 AIN97809.1 - 3.5e-30 105.2 0.2 5.2e-30 104.6 0.2 1.3 1 0 0 1 1 1 1 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term Lactamase_B PF00753.27 AIN97809.1 - 1.2e-22 80.9 0.1 2.1e-22 80.1 0.1 1.4 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_6 PF16661.5 AIN97809.1 - 1.5e-16 60.4 0.0 4.9e-16 58.7 0.0 1.8 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily domain RMMBL PF07521.12 AIN97809.1 - 5e-13 48.8 0.1 1.7e-12 47.1 0.0 2.0 2 0 0 2 2 2 1 Zn-dependent metallo-hydrolase RNA specificity domain Lactamase_B_2 PF12706.7 AIN97809.1 - 1.8e-10 40.7 0.3 1.7e-08 34.2 0.0 2.4 2 0 0 2 2 2 2 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 AIN97809.1 - 0.00099 19.0 0.0 0.004 17.1 0.0 2.0 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Topoisom_I PF01028.20 AIN97810.1 - 6.2e-91 303.8 3.6 6.2e-91 303.8 3.6 1.8 2 0 0 2 2 2 1 Eukaryotic DNA topoisomerase I, catalytic core Topoisom_I_N PF02919.15 AIN97810.1 - 4.8e-90 300.7 1.2 4.8e-90 300.7 1.2 3.5 2 1 0 2 2 2 1 Eukaryotic DNA topoisomerase I, DNA binding fragment DUF3891 PF13030.6 AIN97810.1 - 0.014 15.2 2.6 0.26 11.0 0.9 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3891) LRR_9 PF14580.6 AIN97811.1 - 4.3e-07 29.6 0.1 9.3e-07 28.5 0.1 1.5 1 0 0 1 1 1 1 Leucine-rich repeat LRR_4 PF12799.7 AIN97811.1 - 0.015 15.7 0.0 0.015 15.7 0.0 2.7 3 0 0 3 3 3 0 Leucine Rich repeats (2 copies) TMF_TATA_bd PF12325.8 AIN97811.1 - 0.12 12.6 0.1 0.53 10.5 0.0 2.1 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding zf-RanBP PF00641.18 AIN97812.1 - 2.5e-05 23.5 2.6 2.5e-05 23.5 2.6 1.8 2 0 0 2 2 2 1 Zn-finger in Ran binding protein and others zf-CCCH_4 PF18044.1 AIN97812.1 - 7.5e-05 22.4 1.3 7.5e-05 22.4 1.3 3.0 3 0 0 3 3 3 2 CCCH-type zinc finger zf_CCCH_4 PF18345.1 AIN97812.1 - 0.00054 19.9 1.6 0.0016 18.4 1.6 1.9 1 0 0 1 1 1 1 Zinc finger domain Amidinotransf PF02274.17 AIN97813.1 - 5.2e-11 42.2 0.0 6.8e-11 41.8 0.0 1.2 1 0 0 1 1 1 1 Amidinotransferase Caroten_synth PF04240.12 AIN97813.1 - 0.18 11.6 0.0 0.28 11.0 0.0 1.2 1 0 0 1 1 1 0 Carotenoid biosynthesis protein LRR_6 PF13516.6 AIN97814.1 - 0.14 12.3 0.5 0.99 9.6 0.0 2.6 2 0 0 2 2 2 0 Leucine Rich repeat TPR_12 PF13424.6 AIN97815.1 - 5.8e-33 113.0 18.2 2.6e-08 34.0 4.2 7.1 2 1 5 7 7 7 7 Tetratricopeptide repeat TPR_10 PF13374.6 AIN97815.1 - 4.7e-24 83.5 24.0 4.7e-08 32.6 0.0 7.9 8 0 0 8 8 8 5 Tetratricopeptide repeat TPR_8 PF13181.6 AIN97815.1 - 1.9e-09 37.0 18.8 0.027 14.7 0.1 7.7 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_7 PF13176.6 AIN97815.1 - 0.0029 17.5 16.4 2.2 8.5 0.5 6.7 6 0 0 6 6 6 1 Tetratricopeptide repeat Drf_FH3 PF06367.16 AIN97815.1 - 0.0072 16.0 0.0 0.014 15.0 0.0 1.4 1 0 0 1 1 1 1 Diaphanous FH3 Domain DUF2225 PF09986.9 AIN97815.1 - 0.0084 15.9 0.3 2.3 7.9 0.0 3.2 2 1 0 3 3 3 1 Uncharacterized protein conserved in bacteria (DUF2225) TPR_17 PF13431.6 AIN97815.1 - 0.021 15.2 6.8 37 5.0 0.0 6.0 6 0 0 6 6 6 0 Tetratricopeptide repeat DHR-2 PF06920.13 AIN97815.1 - 0.087 11.4 0.0 0.15 10.7 0.0 1.3 1 0 0 1 1 1 0 Dock homology region 2 TPR_4 PF07721.14 AIN97815.1 - 0.14 12.9 0.5 0.14 12.9 0.5 5.2 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_14 PF13428.6 AIN97815.1 - 0.32 11.9 15.8 7.8 7.6 0.1 5.8 4 1 2 6 6 6 0 Tetratricopeptide repeat TPR_1 PF00515.28 AIN97815.1 - 0.58 10.1 18.8 7.9 6.5 0.0 6.4 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_6 PF13174.6 AIN97815.1 - 0.82 10.4 16.8 2.4 9.0 1.1 6.1 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_2 PF07719.17 AIN97815.1 - 1.4 9.2 23.7 1.6 9.0 0.5 6.7 8 0 0 8 8 8 0 Tetratricopeptide repeat TPR_16 PF13432.6 AIN97815.1 - 1.4 9.6 22.4 7.9 7.2 1.3 6.4 7 0 0 7 7 7 0 Tetratricopeptide repeat DUF1771 PF08590.10 AIN97815.1 - 4.1 7.8 12.0 6.9 7.1 0.0 3.5 4 0 0 4 4 4 0 Domain of unknown function (DUF1771) TIP49 PF06068.13 AIN97816.1 - 1.4e-166 554.0 0.6 1.8e-166 553.7 0.6 1.1 1 0 0 1 1 1 1 TIP49 P-loop domain TIP49_C PF17856.1 AIN97816.1 - 2.4e-19 69.2 0.4 9.1e-19 67.4 0.1 2.3 2 0 0 2 2 1 1 TIP49 AAA-lid domain AAA PF00004.29 AIN97816.1 - 9.7e-12 45.5 0.8 3.7e-07 30.6 0.0 3.0 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 AIN97816.1 - 2.3e-11 43.7 0.0 1.4e-07 31.4 0.0 2.6 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 AIN97816.1 - 7.4e-07 29.5 0.1 0.01 16.1 0.0 2.5 2 1 0 2 2 2 2 AAA domain AAA_16 PF13191.6 AIN97816.1 - 2e-05 25.0 0.4 0.00042 20.7 0.0 2.7 2 1 0 2 2 2 1 AAA ATPase domain Mg_chelatase PF01078.21 AIN97816.1 - 0.00016 21.2 0.2 0.0091 15.4 0.1 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 AIN97816.1 - 0.00028 20.9 0.1 0.11 12.4 0.0 2.5 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_19 PF13245.6 AIN97816.1 - 0.007 16.7 3.4 2.8 8.3 0.1 3.0 3 0 0 3 3 3 2 AAA domain AAA_33 PF13671.6 AIN97816.1 - 0.0072 16.5 0.0 0.024 14.8 0.0 1.8 2 0 0 2 2 2 1 AAA domain DnaB_C PF03796.15 AIN97816.1 - 0.0077 15.6 0.0 0.024 14.0 0.0 1.8 2 0 0 2 2 2 1 DnaB-like helicase C terminal domain AAA_28 PF13521.6 AIN97816.1 - 0.014 15.6 0.0 0.036 14.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 AIN97816.1 - 0.015 14.9 0.0 0.027 14.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.6 AIN97816.1 - 0.019 14.8 0.0 0.074 12.8 0.0 1.9 2 0 0 2 2 2 0 AAA domain ResIII PF04851.15 AIN97816.1 - 0.026 14.5 0.1 1.9 8.5 0.0 2.3 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit AAA_18 PF13238.6 AIN97816.1 - 0.039 14.5 0.1 0.18 12.4 0.0 2.2 3 0 0 3 3 2 0 AAA domain AAA_7 PF12775.7 AIN97816.1 - 0.051 13.1 0.2 0.31 10.5 0.0 2.1 2 1 0 2 2 2 0 P-loop containing dynein motor region IstB_IS21 PF01695.17 AIN97816.1 - 0.063 13.0 0.0 0.19 11.4 0.0 1.8 1 0 0 1 1 1 0 IstB-like ATP binding protein Rad17 PF03215.15 AIN97816.1 - 0.069 13.1 0.0 0.17 11.8 0.0 1.6 1 0 0 1 1 1 0 Rad17 P-loop domain TsaE PF02367.17 AIN97816.1 - 0.074 13.1 0.0 0.16 12.0 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_17 PF13207.6 AIN97816.1 - 0.076 13.4 1.2 1.4 9.4 0.1 3.1 1 1 2 3 3 3 0 AAA domain Sigma54_activat PF00158.26 AIN97816.1 - 0.089 12.5 0.1 10 5.8 0.0 2.5 2 0 0 2 2 2 0 Sigma-54 interaction domain SET PF00856.28 AIN97817.1 - 0.0022 18.4 0.0 0.0033 17.8 0.0 1.3 1 1 0 1 1 1 1 SET domain AAA PF00004.29 AIN97818.1 - 6.8e-47 159.2 0.0 2.3e-37 128.4 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) PEX-1N PF09262.11 AIN97818.1 - 5.2e-16 58.8 0.2 2.3e-15 56.8 0.1 2.2 2 0 0 2 2 1 1 Peroxisome biogenesis factor 1, N-terminal AAA_16 PF13191.6 AIN97818.1 - 1.3e-12 48.4 0.4 0.0014 19.1 0.0 4.4 2 2 1 4 4 4 2 AAA ATPase domain AAA_22 PF13401.6 AIN97818.1 - 6e-09 36.3 0.1 0.005 17.1 0.0 3.1 2 1 1 3 3 3 2 AAA domain AAA_33 PF13671.6 AIN97818.1 - 5.4e-07 29.9 0.0 0.0053 16.9 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_7 PF12775.7 AIN97818.1 - 1.5e-06 27.8 0.0 0.069 12.7 0.1 2.4 2 0 0 2 2 2 2 P-loop containing dynein motor region DUF815 PF05673.13 AIN97818.1 - 1.2e-05 24.6 0.0 0.0035 16.5 0.0 2.7 2 1 0 2 2 2 1 Protein of unknown function (DUF815) AAA_14 PF13173.6 AIN97818.1 - 2.2e-05 24.5 0.0 0.0015 18.6 0.0 2.3 2 0 0 2 2 2 1 AAA domain ATP-synt_ab PF00006.25 AIN97818.1 - 3.3e-05 23.6 0.1 0.094 12.4 0.0 3.0 3 0 0 3 3 3 2 ATP synthase alpha/beta family, nucleotide-binding domain T2SSE PF00437.20 AIN97818.1 - 0.00016 20.8 0.1 0.32 10.0 0.0 2.6 2 1 0 2 2 2 2 Type II/IV secretion system protein AAA_29 PF13555.6 AIN97818.1 - 0.00023 20.9 0.0 0.57 10.0 0.0 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain RNA_helicase PF00910.22 AIN97818.1 - 0.00027 21.3 0.0 0.09 13.2 0.0 3.0 3 0 0 3 3 2 1 RNA helicase ABC_tran PF00005.27 AIN97818.1 - 0.00027 21.4 0.0 0.29 11.7 0.0 2.9 3 0 0 3 3 2 1 ABC transporter AAA_25 PF13481.6 AIN97818.1 - 0.00029 20.4 2.9 1.6 8.2 0.0 4.9 4 1 1 5 5 5 1 AAA domain AAA_5 PF07728.14 AIN97818.1 - 0.00041 20.3 0.1 0.14 12.2 0.0 3.1 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 AIN97818.1 - 0.00047 20.3 0.0 0.0012 19.0 0.0 1.7 2 0 0 2 2 1 1 AAA domain (Cdc48 subfamily) AAA_19 PF13245.6 AIN97818.1 - 0.00049 20.5 0.0 0.15 12.4 0.0 2.9 2 0 0 2 2 2 1 AAA domain Rad17 PF03215.15 AIN97818.1 - 0.00061 19.8 0.0 0.26 11.2 0.0 2.3 2 0 0 2 2 2 1 Rad17 P-loop domain ATPase_2 PF01637.18 AIN97818.1 - 0.00086 19.3 0.1 0.14 12.1 0.0 3.0 2 1 1 3 3 3 1 ATPase domain predominantly from Archaea AAA_28 PF13521.6 AIN97818.1 - 0.001 19.4 0.0 0.29 11.4 0.0 2.7 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.17 AIN97818.1 - 0.0015 18.3 0.1 1.6 8.4 0.0 2.7 3 0 0 3 3 2 1 IstB-like ATP binding protein Vps4_C PF09336.10 AIN97818.1 - 0.0029 17.6 0.0 0.008 16.2 0.0 1.8 1 0 0 1 1 1 1 Vps4 C terminal oligomerisation domain FtsK_SpoIIIE PF01580.18 AIN97818.1 - 0.004 16.6 0.1 0.024 14.0 0.0 2.2 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_lid_3 PF17862.1 AIN97818.1 - 0.0053 16.5 0.0 0.022 14.6 0.0 2.1 1 0 0 1 1 1 1 AAA+ lid domain Sigma54_activat PF00158.26 AIN97818.1 - 0.0057 16.4 0.1 3.2 7.4 0.0 2.9 3 0 0 3 3 3 1 Sigma-54 interaction domain RsgA_GTPase PF03193.16 AIN97818.1 - 0.0059 16.5 0.1 4.1 7.3 0.0 2.5 2 0 0 2 2 2 1 RsgA GTPase AAA_23 PF13476.6 AIN97818.1 - 0.0064 17.0 0.0 3.3 8.2 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_24 PF13479.6 AIN97818.1 - 0.0065 16.2 0.2 1.4 8.6 0.0 3.0 3 0 0 3 3 3 1 AAA domain NACHT PF05729.12 AIN97818.1 - 0.0071 16.3 1.7 3.6 7.5 0.0 3.8 3 1 0 4 4 4 1 NACHT domain Mg_chelatase PF01078.21 AIN97818.1 - 0.012 15.0 0.0 4.8 6.5 0.0 2.5 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI Bac_DnaA PF00308.18 AIN97818.1 - 0.02 14.7 0.0 5.1 6.9 0.0 2.8 3 0 0 3 3 3 0 Bacterial dnaA protein AAA_18 PF13238.6 AIN97818.1 - 0.038 14.5 0.0 1.5 9.4 0.0 2.6 2 0 0 2 2 2 0 AAA domain TniB PF05621.11 AIN97818.1 - 0.045 13.2 0.0 3 7.2 0.0 2.6 2 0 0 2 2 2 0 Bacterial TniB protein YAcAr PF10686.9 AIN97818.1 - 0.053 13.5 0.0 0.17 11.9 0.0 1.9 1 0 0 1 1 1 0 YspA, cpYpsA-related SLOG family TsaE PF02367.17 AIN97818.1 - 0.065 13.2 0.0 6.9 6.7 0.0 2.3 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Zeta_toxin PF06414.12 AIN97818.1 - 0.14 11.4 0.0 20 4.4 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin TrwB_AAD_bind PF10412.9 AIN97818.1 - 0.18 10.7 0.0 4.6 6.0 0.0 2.5 3 0 0 3 3 3 0 Type IV secretion-system coupling protein DNA-binding domain Septin PF00735.18 AIN97818.1 - 0.26 10.5 0.1 7.1 5.8 0.0 2.2 2 0 0 2 2 2 0 Septin DUF3140 PF11338.8 AIN97819.1 - 0.032 14.6 0.0 0.13 12.7 0.0 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3140) LicD PF04991.13 AIN97820.1 - 4.7e-08 33.5 0.0 0.0011 19.1 0.1 2.1 2 0 0 2 2 2 2 LicD family Deltaretro_Tax PF05599.11 AIN97820.1 - 0.0054 17.2 0.0 0.025 15.1 0.0 2.0 2 0 0 2 2 2 1 Deltaretrovirus Tax protein PDCD2_C PF04194.13 AIN97821.1 - 2.7e-22 79.7 0.1 2.7e-22 79.7 0.1 2.5 3 0 0 3 3 3 1 Programmed cell death protein 2, C-terminal putative domain Elf1 PF05129.13 AIN97821.1 - 0.031 14.3 0.9 0.13 12.4 0.2 2.2 2 0 0 2 2 2 0 Transcription elongation factor Elf1 like TF_Zn_Ribbon PF08271.12 AIN97821.1 - 0.14 11.7 2.4 1.9 8.1 0.5 2.6 2 0 0 2 2 2 0 TFIIB zinc-binding Zn-ribbon_8 PF09723.10 AIN97821.1 - 0.19 11.9 2.6 20 5.4 0.2 3.3 3 0 0 3 3 3 0 Zinc ribbon domain DUF2752 PF10825.8 AIN97821.1 - 0.52 10.4 2.8 0.67 10.1 0.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2752) CpXC PF14353.6 AIN97821.1 - 0.75 9.9 4.9 12 6.0 0.0 2.9 2 1 0 2 2 2 0 CpXC protein zf-RRN7 PF11781.8 AIN97821.1 - 2.7 7.8 6.7 1.2 8.9 0.1 2.8 3 0 0 3 3 3 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 Ank_2 PF12796.7 AIN97822.1 - 4.5e-32 110.5 3.1 1.3e-12 48.1 0.0 3.1 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 AIN97822.1 - 6.1e-20 71.3 0.3 1.2e-05 25.8 0.0 5.1 1 1 4 5 5 5 5 Ankyrin repeats (many copies) Ank PF00023.30 AIN97822.1 - 4.3e-19 68.0 1.9 7.8e-05 23.0 0.0 5.4 5 0 0 5 5 5 4 Ankyrin repeat Ank_3 PF13606.6 AIN97822.1 - 1.3e-16 59.0 0.2 0.00073 19.8 0.0 5.5 5 0 0 5 5 5 3 Ankyrin repeat Ank_5 PF13857.6 AIN97822.1 - 5.3e-15 55.3 4.4 0.00035 20.8 0.4 4.4 1 1 3 4 4 4 4 Ankyrin repeats (many copies) DUF3372 PF11852.8 AIN97822.1 - 0.044 13.3 0.0 0.07 12.6 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3372) Integrin_beta PF00362.18 AIN97824.1 - 0.031 13.9 0.0 9.4 5.8 0.0 2.5 2 1 0 2 2 2 0 Integrin beta chain VWA domain PI3_PI4_kinase PF00454.27 AIN97825.1 - 2.4e-35 122.6 0.0 7.1e-24 85.0 0.0 2.3 1 1 1 2 2 2 2 Phosphatidylinositol 3- and 4-kinase DUF4135 PF13575.6 AIN97825.1 - 0.0044 16.4 0.0 0.0074 15.7 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4135) PfkB PF00294.24 AIN97826.1 - 2.7e-44 151.7 0.1 3.8e-43 147.9 0.1 2.0 1 1 0 1 1 1 1 pfkB family carbohydrate kinase Complex1_LYR PF05347.15 AIN97827.1 - 4.5e-09 36.2 0.9 6.9e-09 35.6 0.9 1.3 1 0 0 1 1 1 1 Complex 1 protein (LYR family) DUF3336 PF11815.8 AIN97828.1 - 6.4e-20 71.3 0.1 1.1e-19 70.5 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3336) Patatin PF01734.22 AIN97828.1 - 2.5e-07 31.1 3.3 8.6e-07 29.3 3.3 1.9 1 1 0 1 1 1 1 Patatin-like phospholipase Ribosomal_L25p PF01386.19 AIN97828.1 - 0.074 13.6 0.0 2.6 8.6 0.0 2.3 2 0 0 2 2 2 0 Ribosomal L25p family Metallophos PF00149.28 AIN97829.1 - 1.7e-06 28.7 0.0 3e-06 27.9 0.0 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 AIN97829.1 - 0.009 16.2 0.0 0.11 12.7 0.0 2.2 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain ChAPs PF09295.10 AIN97829.1 - 0.15 11.0 0.0 0.22 10.5 0.0 1.1 1 0 0 1 1 1 0 ChAPs (Chs5p-Arf1p-binding proteins) FixS PF03597.15 AIN97829.1 - 1 9.1 3.7 3 7.6 3.7 1.8 1 0 0 1 1 1 0 Cytochrome oxidase maturation protein cbb3-type DUF4131 PF13567.6 AIN97829.1 - 5.7 6.6 5.9 0.26 10.9 0.4 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) zf-U1 PF06220.12 AIN97830.1 - 0.17 11.7 0.3 0.17 11.7 0.3 1.6 2 0 0 2 2 2 0 U1 zinc finger MHYT PF03707.16 AIN97830.1 - 1.3 9.2 6.4 0.41 10.9 0.8 2.2 2 0 0 2 2 2 0 Bacterial signalling protein N terminal repeat FixS PF03597.15 AIN97831.1 - 0.19 11.4 0.4 0.19 11.4 0.4 1.5 2 0 0 2 2 2 0 Cytochrome oxidase maturation protein cbb3-type Ribosomal_L21e PF01157.18 AIN97832.1 - 1.4e-40 137.2 3.1 2.1e-40 136.7 3.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L21e EMP70 PF02990.16 AIN97833.1 - 5.8e-133 444.3 6.4 7.4e-133 444.0 6.4 1.1 1 0 0 1 1 1 1 Endomembrane protein 70 ATP-synt_ab PF00006.25 AIN97834.1 - 2.1e-105 351.1 0.0 3.5e-105 350.3 0.0 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_Xtn PF16886.5 AIN97834.1 - 9.4e-45 151.4 0.5 2e-44 150.3 0.1 1.8 2 0 0 2 2 2 1 ATPsynthase alpha/beta subunit N-term extension ATP-synt_ab_N PF02874.23 AIN97834.1 - 3.1e-14 53.2 1.8 3.1e-14 53.2 1.8 2.7 3 0 0 3 3 3 1 ATP synthase alpha/beta family, beta-barrel domain DUF2737 PF10930.8 AIN97834.1 - 0.047 13.3 0.3 15 5.2 0.1 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF2737) Ribosomal_L13 PF00572.18 AIN97835.1 - 1.2e-28 99.9 0.1 1.5e-28 99.5 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L13 Ins_P5_2-kin PF06090.12 AIN97837.1 - 2e-26 93.2 0.0 2.6e-26 92.8 0.0 1.3 1 0 0 1 1 1 1 Inositol-pentakisphosphate 2-kinase CDtoxinA PF03498.14 AIN97837.1 - 0.47 10.0 1.9 5.8 6.5 0.1 2.7 2 1 1 3 3 3 0 Cytolethal distending toxin A/C domain ART-PolyVal PF18760.1 AIN97838.1 - 0.011 16.7 1.1 0.019 16.0 1.1 1.5 1 1 0 1 1 1 0 ADP-Ribosyltransferase in polyvalent proteins DUF501 PF04417.12 AIN97839.1 - 7.5e-28 97.1 0.3 1.5e-27 96.1 0.3 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF501) Aminotran_1_2 PF00155.21 AIN97841.1 - 1.4e-44 152.7 0.0 1.7e-44 152.5 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II KH_5 PF13184.6 AIN97841.1 - 0.62 10.2 2.9 11 6.1 0.1 2.6 3 0 0 3 3 3 0 NusA-like KH domain DUF5349 PF17298.2 AIN97842.1 - 0.81 9.4 3.8 1.3 8.7 3.8 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5349) LIM PF00412.22 AIN97843.1 - 0.027 14.7 7.8 0.027 14.7 7.8 2.0 2 0 0 2 2 2 0 LIM domain zf-HYPF PF07503.12 AIN97843.1 - 0.082 12.7 9.9 0.033 14.0 4.0 3.0 3 0 0 3 3 3 0 HypF finger Lar_restr_allev PF14354.6 AIN97843.1 - 3 8.3 10.1 3.7 8.0 0.1 2.8 1 1 1 2 2 2 0 Restriction alleviation protein Lar Actin PF00022.19 AIN97844.1 - 1.2e-37 129.5 0.0 1.5e-33 116.0 0.0 3.0 2 1 0 2 2 2 2 Actin FtsA PF14450.6 AIN97844.1 - 0.0031 17.9 0.0 0.0045 17.4 0.0 1.4 1 0 0 1 1 1 1 Cell division protein FtsA PGM_PMM_I PF02878.16 AIN97846.1 - 1e-35 122.4 0.1 2.2e-35 121.4 0.1 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_II PF02879.16 AIN97846.1 - 9.2e-21 74.4 0.0 2.4e-20 73.1 0.0 1.8 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_III PF02880.16 AIN97846.1 - 2.9e-14 53.2 0.1 1.7e-13 50.8 0.1 2.3 3 0 0 3 3 3 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_IV PF00408.20 AIN97846.1 - 0.00022 21.3 0.0 0.00069 19.7 0.0 1.9 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain PALB2_WD40 PF16756.5 AIN97847.1 - 0.14 11.1 0.7 0.4 9.5 0.7 1.7 1 0 0 1 1 1 0 Partner and localizer of BRCA2 WD40 domain PQQ_3 PF13570.6 AIN97847.1 - 0.72 10.4 4.4 9.6 6.8 0.4 4.1 3 0 0 3 3 3 0 PQQ-like domain APO_RNA-bind PF05634.11 AIN97849.1 - 0.086 12.2 0.0 0.12 11.7 0.0 1.2 1 0 0 1 1 1 0 APO RNA-binding Ribosomal_L14 PF00238.19 AIN97850.1 - 1.9e-21 76.4 0.1 3.2e-21 75.7 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e TPR_1 PF00515.28 AIN97851.1 - 2.2e-07 30.4 7.9 0.051 13.4 0.0 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 AIN97851.1 - 4.8e-06 26.3 10.3 0.094 12.9 0.2 4.0 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_11 PF13414.6 AIN97851.1 - 0.00013 21.6 0.1 0.018 14.7 0.0 2.9 3 0 0 3 3 3 1 TPR repeat TPR_19 PF14559.6 AIN97851.1 - 0.0016 18.9 0.1 0.15 12.6 0.1 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.6 AIN97851.1 - 0.0081 16.4 4.4 14 6.0 0.0 3.9 2 1 2 4 4 4 1 Tetratricopeptide repeat ANAPC3 PF12895.7 AIN97851.1 - 0.011 16.0 5.6 0.89 9.8 1.8 3.5 2 1 2 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 BTAD PF03704.17 AIN97851.1 - 0.036 14.5 0.5 0.92 9.9 0.0 2.3 2 0 0 2 2 2 0 Bacterial transcriptional activator domain TPR_14 PF13428.6 AIN97851.1 - 0.14 13.0 2.0 31 5.8 0.1 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.6 AIN97851.1 - 0.15 12.7 4.8 12 6.6 0.1 3.0 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.6 AIN97851.1 - 0.3 11.8 2.5 17 6.3 0.4 3.4 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.6 AIN97851.1 - 0.51 10.7 6.8 17 5.9 0.0 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF745 PF05335.13 AIN97852.1 - 4.5e-06 26.5 14.4 0.00037 20.3 7.2 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF745) Spc7 PF08317.11 AIN97852.1 - 4e-05 22.6 1.2 4e-05 22.6 1.2 1.6 2 0 0 2 2 2 1 Spc7 kinetochore protein TMCO5 PF14992.6 AIN97852.1 - 0.036 13.6 2.2 1.3 8.5 0.0 2.2 2 0 0 2 2 2 0 TMCO5 family DUF4201 PF13870.6 AIN97852.1 - 0.12 12.1 6.9 0.031 14.0 3.6 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4201) DUF2951 PF11166.8 AIN97852.1 - 0.32 11.2 1.5 13 6.0 0.3 2.4 3 0 0 3 3 2 0 Protein of unknown function (DUF2951) CENP-H PF05837.12 AIN97852.1 - 0.34 11.3 14.6 1.3 9.5 0.2 2.5 2 1 0 2 2 2 0 Centromere protein H (CENP-H) Sec2p PF06428.11 AIN97852.1 - 0.67 10.0 9.0 0.33 10.9 6.1 2.0 2 0 0 2 2 2 0 GDP/GTP exchange factor Sec2p THOC7 PF05615.13 AIN97852.1 - 0.97 9.7 11.6 0.31 11.3 6.0 2.5 2 1 0 2 2 2 0 Tho complex subunit 7 Spc24 PF08286.11 AIN97852.1 - 1.1 9.5 7.0 2.1 8.6 3.2 2.2 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 Exonuc_VII_L PF02601.15 AIN97852.1 - 1.8 8.0 10.1 3.2 7.3 10.1 1.4 1 1 0 1 1 1 0 Exonuclease VII, large subunit ADIP PF11559.8 AIN97852.1 - 2.4 8.2 11.5 2.6 8.1 7.0 2.2 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding PRKG1_interact PF15898.5 AIN97852.1 - 4.5 8.2 13.0 21 6.1 7.0 2.7 2 1 0 2 2 2 0 cGMP-dependent protein kinase interacting domain DUF3287 PF11690.8 AIN97852.1 - 8.1 6.2 8.2 0.31 10.7 0.3 2.3 2 1 1 3 3 3 0 Protein of unknown function (DUF3287) MIP PF00230.20 AIN97854.1 - 1.6e-33 116.3 19.2 9.1e-33 113.9 19.2 1.8 1 1 0 1 1 1 1 Major intrinsic protein LSM PF01423.22 AIN97855.1 - 7.5e-12 44.8 0.4 9.3e-12 44.5 0.4 1.2 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 AIN97855.1 - 0.00014 21.9 0.1 0.00022 21.3 0.1 1.3 1 0 0 1 1 1 1 Ataxin 2 SM domain LSM14 PF12701.7 AIN97855.1 - 0.14 12.3 0.1 0.2 11.8 0.1 1.2 1 0 0 1 1 1 0 Scd6-like Sm domain DnaJ PF00226.31 AIN97856.1 - 4.7e-18 65.1 0.0 9.2e-18 64.1 0.0 1.5 1 0 0 1 1 1 1 DnaJ domain Fer4_20 PF14691.6 AIN97856.1 - 0.087 12.6 0.6 0.37 10.6 0.3 2.1 2 0 0 2 2 2 0 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster AAA_6 PF12774.7 AIN97857.1 - 5.1e-153 508.8 0.0 4.9e-152 505.6 0.0 2.8 3 0 0 3 3 3 1 Hydrolytic ATP binding site of dynein motor region DHC_N1 PF08385.12 AIN97857.1 - 6.1e-137 457.6 1.9 6.1e-137 457.6 1.9 3.1 3 0 0 3 3 3 1 Dynein heavy chain, N-terminal region 1 DHC_N2 PF08393.13 AIN97857.1 - 9.7e-113 377.2 7.0 9.7e-113 377.2 7.0 5.3 7 0 0 7 7 6 1 Dynein heavy chain, N-terminal region 2 AAA_8 PF12780.7 AIN97857.1 - 1.6e-100 335.7 0.0 3.8e-100 334.5 0.0 1.7 1 0 0 1 1 1 1 P-loop containing dynein motor region D4 Dynein_C PF18199.1 AIN97857.1 - 1.5e-81 274.0 0.2 4.5e-81 272.4 0.2 1.9 1 0 0 1 1 1 1 Dynein heavy chain C-terminal domain AAA_9 PF12781.7 AIN97857.1 - 8.2e-74 247.4 0.0 8.2e-74 247.4 0.0 3.7 4 0 0 4 4 3 1 ATP-binding dynein motor region AAA_7 PF12775.7 AIN97857.1 - 6.6e-64 214.7 7.3 2.5e-46 157.5 0.0 4.8 5 0 0 5 5 5 3 P-loop containing dynein motor region AAA_lid_11 PF18198.1 AIN97857.1 - 2.1e-49 167.5 0.0 5.9e-49 166.0 0.0 1.9 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain Dynein_heavy PF03028.15 AIN97857.1 - 1.7e-43 147.5 0.1 4.9e-42 142.8 0.1 3.1 2 0 0 2 2 2 1 Dynein heavy chain region D6 P-loop domain MT PF12777.7 AIN97857.1 - 1.5e-41 142.6 9.1 2.6e-41 141.8 9.1 1.4 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_5 PF07728.14 AIN97857.1 - 8.6e-22 77.6 3.4 3.9e-08 33.4 0.0 7.2 6 2 0 6 6 5 3 AAA domain (dynein-related subfamily) Dynein_AAA_lid PF17852.1 AIN97857.1 - 2.8e-21 75.9 0.0 1.7e-20 73.4 0.0 2.6 2 0 0 2 2 2 1 Dynein heavy chain AAA lid domain AAA_lid_1 PF17857.1 AIN97857.1 - 1.5e-14 54.0 0.0 6.4e-14 52.0 0.0 2.1 1 0 0 1 1 1 1 AAA+ lid domain AAA PF00004.29 AIN97857.1 - 2e-07 31.5 7.1 0.75 10.2 0.0 6.6 7 0 0 7 7 5 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 AIN97857.1 - 5.6e-07 30.1 7.8 0.12 12.7 0.0 7.0 6 1 0 6 6 5 1 AAA ATPase domain AAA_33 PF13671.6 AIN97857.1 - 0.00023 21.4 7.8 0.17 12.0 0.0 5.3 5 0 0 5 5 4 2 AAA domain RsgA_GTPase PF03193.16 AIN97857.1 - 0.00028 20.8 1.4 0.036 14.0 0.2 3.6 3 0 0 3 3 3 1 RsgA GTPase COG5 PF10392.9 AIN97857.1 - 0.0016 18.6 1.9 0.098 12.8 0.8 3.7 2 0 0 2 2 2 1 Golgi transport complex subunit 5 AAA_18 PF13238.6 AIN97857.1 - 0.006 17.1 3.5 4.6 7.8 0.0 4.9 5 0 0 5 5 4 1 AAA domain AAA_22 PF13401.6 AIN97857.1 - 0.0069 16.7 10.3 0.74 10.1 0.0 5.9 7 0 0 7 7 4 1 AAA domain Rad17 PF03215.15 AIN97857.1 - 0.0094 15.9 1.2 1.4 8.8 0.1 3.6 4 0 0 4 4 3 1 Rad17 P-loop domain AAA_29 PF13555.6 AIN97857.1 - 0.053 13.3 0.4 1.6 8.6 0.1 2.7 2 0 0 2 2 2 0 P-loop containing region of AAA domain DUF406 PF04175.12 AIN97857.1 - 0.054 14.0 3.4 0.13 12.8 0.2 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF406) ABC_tran PF00005.27 AIN97857.1 - 0.09 13.3 7.5 1.3 9.5 0.1 4.4 5 0 0 5 5 3 0 ABC transporter RNA_helicase PF00910.22 AIN97857.1 - 0.094 13.1 2.4 4.9 7.6 0.0 3.3 3 0 0 3 3 3 0 RNA helicase AAA_30 PF13604.6 AIN97857.1 - 0.11 12.3 5.7 5.6 6.6 0.1 3.7 4 0 0 4 4 4 0 AAA domain DUF1612 PF07756.12 AIN97857.1 - 0.96 9.7 5.6 4.3 7.6 5.6 2.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1612) HATPase_c PF02518.26 AIN97859.1 - 6.3e-10 39.6 0.0 1.3e-09 38.5 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase NMO PF03060.15 AIN97859.1 - 0.15 11.4 0.0 0.22 10.9 0.0 1.2 1 0 0 1 1 1 0 Nitronate monooxygenase FAM222A PF15258.6 AIN97859.1 - 0.25 10.4 0.5 0.51 9.4 0.5 1.4 1 0 0 1 1 1 0 Protein family of FAM222A Pet191_N PF10203.9 AIN97860.1 - 2.9e-09 37.1 3.1 4.2e-09 36.6 3.1 1.3 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein PET191 CX9C PF16860.5 AIN97860.1 - 0.49 10.4 4.8 2.3 8.3 0.3 2.6 1 1 1 2 2 2 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, NIF PF03031.18 AIN97861.1 - 6.9e-27 94.1 0.0 1e-26 93.6 0.0 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase DUF705 PF05152.12 AIN97861.1 - 3.5e-05 23.4 0.0 5.3e-05 22.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF705) SWI-SNF_Ssr4 PF08549.10 AIN97861.1 - 0.06 12.0 0.4 0.11 11.1 0.4 1.3 1 0 0 1 1 1 0 Fungal domain of unknown function (DUF1750) PI3_PI4_kinase PF00454.27 AIN97863.1 - 7.8e-57 192.9 0.1 1.9e-56 191.7 0.1 1.7 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FAT PF02259.23 AIN97863.1 - 6.3e-24 84.8 0.1 1.3e-23 83.8 0.1 1.6 1 0 0 1 1 1 1 FAT domain FRB_dom PF08771.11 AIN97863.1 - 5e-13 49.3 2.7 1.1e-12 48.2 0.4 3.0 3 0 0 3 3 3 1 FKBP12-rapamycin binding domain DUF3385 PF11865.8 AIN97863.1 - 2e-12 47.3 4.2 1.1e-11 44.9 0.4 3.3 2 1 0 2 2 2 1 Domain of unknown function (DUF3385) FATC PF02260.20 AIN97863.1 - 4e-11 42.5 0.4 1.2e-10 41.1 0.0 2.1 2 0 0 2 2 2 1 FATC domain PDZ_6 PF17820.1 AIN97863.1 - 4.8e-06 26.3 0.1 1.8e-05 24.5 0.1 2.1 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 AIN97863.1 - 0.001 19.3 0.1 0.0025 18.1 0.1 1.5 1 0 0 1 1 1 1 PDZ domain IFRD PF05004.13 AIN97863.1 - 0.01 15.0 1.2 0.23 10.5 0.2 3.1 2 0 0 2 2 2 0 Interferon-related developmental regulator (IFRD) PDZ_2 PF13180.6 AIN97863.1 - 0.054 13.8 0.0 0.14 12.5 0.0 1.6 1 0 0 1 1 1 0 PDZ domain HEAT_2 PF13646.6 AIN97863.1 - 0.14 12.6 13.0 1.1 9.8 0.4 5.9 5 1 1 6 6 5 0 HEAT repeats TPR_11 PF13414.6 AIN97863.1 - 0.17 11.6 0.0 0.46 10.2 0.0 1.7 1 0 0 1 1 1 0 TPR repeat Nsp1_C PF05064.13 AIN97864.1 - 0.071 12.9 0.1 0.11 12.3 0.1 1.2 1 0 0 1 1 1 0 Nsp1-like C-terminal region SHIPPO-rpt PF07004.12 AIN97864.1 - 0.18 12.8 1.3 0.54 11.3 1.3 1.9 1 0 0 1 1 1 0 Sperm-tail PG-rich repeat Tmemb_cc2 PF10267.9 AIN97864.1 - 1.4 8.0 3.3 1.1 8.4 1.2 1.5 1 1 1 2 2 2 0 Predicted transmembrane and coiled-coil 2 protein PIG-Y PF15159.6 AIN97865.1 - 6.5e-07 30.2 0.9 8.7e-07 29.8 0.9 1.2 1 0 0 1 1 1 1 Phosphatidylinositol N-acetylglucosaminyltransferase subunit Y HECT PF00632.25 AIN97867.1 - 4.7e-44 151.1 0.0 1.3e-43 149.6 0.0 1.7 1 1 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Gal4_dimer PF03902.13 AIN97867.1 - 0.09 13.0 0.2 0.22 11.7 0.2 1.6 1 0 0 1 1 1 0 Gal4-like dimerisation domain C1_2 PF03107.16 AIN97867.1 - 1.7 9.0 14.8 5.4 7.4 14.8 1.9 1 0 0 1 1 1 0 C1 domain Adaptin_N PF01602.20 AIN97868.1 - 1.7e-72 244.7 5.0 2.2e-72 244.3 5.0 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptinC2 PF02883.20 AIN97868.1 - 4.4e-09 36.6 0.1 1e-08 35.5 0.1 1.5 1 0 0 1 1 1 1 Adaptin C-terminal domain PMEI PF04043.15 AIN97868.1 - 3.3 8.0 7.1 0.88 9.9 0.2 2.9 2 1 0 3 3 3 0 Plant invertase/pectin methylesterase inhibitor Ribosomal_L7Ae PF01248.26 AIN97869.1 - 7.3e-19 67.3 0.5 9.1e-19 67.0 0.5 1.2 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Rgp1 PF08737.10 AIN97870.1 - 6e-09 35.6 0.0 6.5e-05 22.3 0.0 2.1 2 0 0 2 2 2 2 Rgp1 Peptidase_C78 PF07910.13 AIN97871.1 - 4.8e-49 166.7 0.0 6.8e-49 166.2 0.0 1.2 1 0 0 1 1 1 1 Peptidase family C78 Peptidase_C54 PF03416.19 AIN97871.1 - 0.12 11.7 0.1 0.48 9.8 0.0 1.9 2 0 0 2 2 2 0 Peptidase family C54 DUF445 PF04286.12 AIN97873.1 - 0.018 14.9 0.2 0.023 14.5 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF445) FANCI_S1-cap PF14674.6 AIN97873.1 - 0.098 12.8 0.4 3.8 7.7 0.0 2.5 2 0 0 2 2 2 0 FANCI solenoid 1 cap UNC45-central PF11701.8 AIN97873.1 - 0.16 11.9 1.5 0.5 10.3 1.5 1.9 1 1 0 1 1 1 0 Myosin-binding striated muscle assembly central Prenyltrans PF00432.21 AIN97874.1 - 3.1e-71 234.7 13.4 1.8e-14 53.2 0.3 6.0 6 0 0 6 6 6 5 Prenyltransferase and squalene oxidase repeat SQHop_cyclase_N PF13249.6 AIN97874.1 - 5.6e-09 35.5 0.0 0.011 14.8 0.0 4.1 1 1 3 4 4 4 3 Squalene-hopene cyclase N-terminal domain SQHop_cyclase_C PF13243.6 AIN97874.1 - 4.6e-05 22.7 0.7 0.0094 15.1 0.0 3.2 1 1 3 4 4 4 2 Squalene-hopene cyclase C-terminal domain TED_complement PF07678.14 AIN97874.1 - 0.22 10.5 0.1 3.3 6.6 0.0 2.9 3 2 1 4 4 4 0 A-macroglobulin TED domain C12orf66_like PF09404.10 AIN97876.1 - 0.063 12.1 0.1 0.11 11.3 0.1 1.3 1 0 0 1 1 1 0 KICSTOR complex C12orf66 like Phage_tail_L PF05100.12 AIN97876.1 - 0.19 11.0 0.0 0.46 9.8 0.0 1.6 2 0 0 2 2 2 0 Phage minor tail protein L UCH PF00443.29 AIN97877.1 - 6.3e-37 127.5 0.3 1.1e-36 126.7 0.1 1.5 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 AIN97877.1 - 1.6e-13 50.9 0.0 5.5e-13 49.2 0.0 1.8 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Peptidase_C98 PF15499.6 AIN97877.1 - 0.056 12.9 0.3 0.13 11.7 0.0 1.6 2 0 0 2 2 2 0 Ubiquitin-specific peptidase-like, SUMO isopeptidase Casc1_N PF15927.5 AIN97878.1 - 2.2e-09 37.3 4.0 1.7e-08 34.4 4.0 2.1 1 1 0 1 1 1 1 Cancer susceptibility candidate 1 N-terminus DnaJ PF00226.31 AIN97879.1 - 9.4e-07 28.9 0.1 4.3e-06 26.8 0.0 2.0 2 0 0 2 2 2 1 DnaJ domain GRIP PF01465.20 AIN97880.1 - 7.1e-11 41.8 0.9 6.9e-10 38.7 0.1 2.6 2 0 0 2 2 2 1 GRIP domain SesA PF17107.5 AIN97880.1 - 0.15 12.2 4.9 0.66 10.2 2.8 2.7 2 1 0 2 2 2 0 N-terminal domain on NACHT_NTPase and P-loop NTPases Acetyltransf_11 PF13720.6 AIN97880.1 - 0.37 11.3 1.8 41 4.7 0.0 3.4 2 0 0 2 2 2 0 Udp N-acetylglucosamine O-acyltransferase; Domain 2 Lipoprotein_6 PF01441.19 AIN97880.1 - 0.49 10.4 2.9 2.7 8.0 0.6 2.5 2 1 0 2 2 2 0 Lipoprotein MPS2 PF17060.5 AIN97880.1 - 0.66 9.2 7.8 0.41 9.9 5.2 1.9 2 0 0 2 2 2 0 Monopolar spindle protein 2 PIN_8 PF18476.1 AIN97880.1 - 2.7 7.8 12.4 7.3 6.4 8.2 2.5 1 1 1 2 2 2 0 PIN like domain DUF1664 PF07889.12 AIN97880.1 - 3 7.9 13.5 2.2 8.3 5.8 3.2 2 2 1 3 3 3 0 Protein of unknown function (DUF1664) Baculo_PEP_C PF04513.12 AIN97880.1 - 3.2 7.8 12.7 0.51 10.4 5.8 2.8 2 2 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus HIP1_clath_bdg PF16515.5 AIN97880.1 - 3.6 8.2 39.6 0.12 13.0 7.4 4.7 4 1 1 5 5 5 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Prominin PF05478.11 AIN97880.1 - 5 4.9 14.4 0.92 7.4 10.3 1.6 2 0 0 2 2 2 0 Prominin ATG16 PF08614.11 AIN97880.1 - 5.3 7.2 37.7 2.4 8.4 21.6 3.4 2 1 1 3 3 3 0 Autophagy protein 16 (ATG16) FliD_N PF02465.18 AIN97880.1 - 5.4 7.8 14.0 14 6.4 0.4 3.2 2 1 0 2 2 2 0 Flagellar hook-associated protein 2 N-terminus DUF16 PF01519.16 AIN97880.1 - 7.3 7.1 13.0 0.089 13.3 3.2 2.7 3 0 0 3 3 3 0 Protein of unknown function DUF16 Membralin PF09746.9 AIN97880.1 - 7.4 5.5 7.9 14 4.6 7.9 1.4 1 0 0 1 1 1 0 Tumour-associated protein Cauli_AT PF03233.13 AIN97880.1 - 7.4 6.5 8.2 11 5.9 4.4 2.7 2 1 1 3 3 3 0 Aphid transmission protein BLOC1_2 PF10046.9 AIN97880.1 - 9.3 6.6 17.1 1.5 9.2 5.3 4.0 4 1 1 5 5 5 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Peptidase_C50 PF03568.17 AIN97882.1 - 0.026 13.7 0.0 0.048 12.8 0.0 1.3 1 0 0 1 1 1 0 Peptidase family C50 Abhydrolase_1 PF00561.20 AIN97883.1 - 1.6e-05 24.7 0.0 6.8e-05 22.6 0.0 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 AIN97883.1 - 4.6e-05 22.8 0.0 6.8e-05 22.3 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 AIN97883.1 - 0.00053 20.6 0.1 0.00068 20.3 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF4892 PF16234.5 AIN97883.1 - 0.013 15.0 0.0 0.022 14.2 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4892) EMC1_C PF07774.13 AIN97884.1 - 1.9e-47 161.7 0.0 5.4e-47 160.2 0.0 1.8 2 0 0 2 2 2 1 ER membrane protein complex subunit 1, C-terminal PQQ_2 PF13360.6 AIN97884.1 - 0.022 14.3 2.4 0.46 10.0 1.2 3.3 3 1 0 3 3 3 0 PQQ-like domain PQQ_3 PF13570.6 AIN97884.1 - 1.1 9.9 3.4 4 8.1 0.1 3.8 3 0 0 3 3 3 0 PQQ-like domain REPA_OB_2 PF16900.5 AIN97886.1 - 0.00052 19.9 0.2 0.0012 18.7 0.2 1.6 1 1 0 1 1 1 1 Replication protein A OB domain AAA_6 PF12774.7 AIN97887.1 - 1.3e-126 422.1 0.0 5e-126 420.1 0.0 2.2 1 0 0 1 1 1 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 AIN97887.1 - 9.2e-108 360.9 4.5 9.2e-108 360.9 4.5 5.0 4 1 1 5 5 5 1 Dynein heavy chain, N-terminal region 2 AAA_9 PF12781.7 AIN97887.1 - 1.1e-64 217.6 0.5 1.1e-64 217.6 0.5 2.9 2 0 0 2 2 1 1 ATP-binding dynein motor region AAA_8 PF12780.7 AIN97887.1 - 3.6e-46 157.6 0.9 8.2e-44 149.9 0.0 3.2 2 0 0 2 2 2 1 P-loop containing dynein motor region D4 DHC_N1 PF08385.12 AIN97887.1 - 5.6e-35 121.0 0.0 5.6e-35 121.0 0.0 3.6 4 0 0 4 4 3 1 Dynein heavy chain, N-terminal region 1 AAA_5 PF07728.14 AIN97887.1 - 6.2e-32 110.5 0.0 6.5e-21 74.8 0.0 5.5 4 1 0 4 4 4 3 AAA domain (dynein-related subfamily) AAA_7 PF12775.7 AIN97887.1 - 2e-29 102.4 0.1 3.5e-24 85.3 0.0 3.7 3 0 0 3 3 3 2 P-loop containing dynein motor region Dynein_heavy PF03028.15 AIN97887.1 - 3.9e-29 101.2 0.0 2.8e-28 98.4 0.0 2.7 2 0 0 2 2 1 1 Dynein heavy chain region D6 P-loop domain AAA_lid_11 PF18198.1 AIN97887.1 - 9e-29 100.4 0.0 1.8e-28 99.4 0.0 1.5 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain MT PF12777.7 AIN97887.1 - 1.8e-26 93.0 12.7 5.9e-26 91.3 12.7 2.0 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor Dynein_C PF18199.1 AIN97887.1 - 1.9e-23 83.2 0.0 6.8e-23 81.4 0.0 2.0 1 0 0 1 1 1 1 Dynein heavy chain C-terminal domain AAA_16 PF13191.6 AIN97887.1 - 1.1e-14 55.2 0.0 5.9e-06 26.8 0.0 5.9 3 0 0 3 3 3 2 AAA ATPase domain AAA PF00004.29 AIN97887.1 - 7.7e-11 42.5 0.0 0.081 13.3 0.0 4.4 3 0 0 3 3 3 3 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 AIN97887.1 - 1.3e-10 41.7 0.1 0.0037 17.5 0.0 4.7 3 0 0 3 3 3 2 AAA domain RsgA_GTPase PF03193.16 AIN97887.1 - 7.6e-07 29.2 0.1 0.0003 20.7 0.1 3.3 2 0 0 2 2 2 1 RsgA GTPase AAA_24 PF13479.6 AIN97887.1 - 1.1e-06 28.5 0.1 0.11 12.2 0.0 3.8 3 0 0 3 3 3 1 AAA domain RNA_helicase PF00910.22 AIN97887.1 - 1.8e-06 28.3 0.0 0.71 10.3 0.0 3.7 3 0 0 3 3 3 1 RNA helicase AAA_30 PF13604.6 AIN97887.1 - 6.5e-06 26.0 0.1 0.022 14.5 0.0 3.6 3 0 0 3 3 3 1 AAA domain AAA_33 PF13671.6 AIN97887.1 - 7.9e-06 26.1 0.1 0.12 12.5 0.0 3.9 3 0 0 3 3 3 2 AAA domain ABC_tran PF00005.27 AIN97887.1 - 1.2e-05 25.8 6.6 0.0053 17.3 0.0 4.8 5 0 0 5 5 3 1 ABC transporter AAA_28 PF13521.6 AIN97887.1 - 1.6e-05 25.2 0.0 1.9 8.7 0.0 4.3 3 0 0 3 3 3 2 AAA domain IIGP PF05049.13 AIN97887.1 - 3.7e-05 23.0 1.6 0.0098 15.0 0.0 3.1 3 0 0 3 3 3 1 Interferon-inducible GTPase (IIGP) AAA_lid_7 PF17867.1 AIN97887.1 - 8.8e-05 22.7 0.2 0.001 19.2 0.0 3.1 2 0 0 2 2 1 1 Midasin AAA lid domain NACHT PF05729.12 AIN97887.1 - 0.00011 22.1 0.8 0.41 10.5 0.0 3.3 3 0 0 3 3 2 2 NACHT domain AAA_18 PF13238.6 AIN97887.1 - 0.00014 22.4 3.2 0.21 12.2 0.0 5.3 5 0 0 5 5 4 1 AAA domain Rad17 PF03215.15 AIN97887.1 - 0.0002 21.3 0.7 0.045 13.7 0.1 3.8 3 0 0 3 3 3 1 Rad17 P-loop domain AAA_14 PF13173.6 AIN97887.1 - 0.00045 20.3 0.0 0.31 11.1 0.0 3.8 3 0 0 3 3 3 1 AAA domain IstB_IS21 PF01695.17 AIN97887.1 - 0.00064 19.5 0.1 0.1 12.3 0.0 3.9 4 0 0 4 4 4 1 IstB-like ATP binding protein cobW PF02492.19 AIN97887.1 - 0.00073 19.2 2.4 1.4 8.5 0.0 3.8 3 0 0 3 3 3 1 CobW/HypB/UreG, nucleotide-binding domain AAA_29 PF13555.6 AIN97887.1 - 0.00073 19.2 0.1 0.038 13.7 0.0 3.1 3 0 0 3 3 2 1 P-loop containing region of AAA domain AAA_25 PF13481.6 AIN97887.1 - 0.0009 18.9 0.3 12 5.5 0.0 4.6 4 0 0 4 4 3 0 AAA domain Sigma54_activat PF00158.26 AIN97887.1 - 0.0012 18.5 0.0 0.25 11.0 0.0 2.6 2 0 0 2 2 2 1 Sigma-54 interaction domain Mg_chelatase PF01078.21 AIN97887.1 - 0.0018 17.7 0.1 3.2 7.1 0.0 3.3 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI T2SSE PF00437.20 AIN97887.1 - 0.0019 17.3 0.0 0.07 12.2 0.0 2.8 2 0 0 2 2 2 1 Type II/IV secretion system protein Roc PF08477.13 AIN97887.1 - 0.0073 16.5 0.2 5.4 7.3 0.0 3.2 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_21 PF13304.6 AIN97887.1 - 0.0076 16.1 0.0 0.029 14.2 0.0 2.0 2 0 0 2 2 1 1 AAA domain, putative AbiEii toxin, Type IV TA system TsaE PF02367.17 AIN97887.1 - 0.012 15.6 0.1 2.3 8.2 0.0 3.8 4 0 0 4 4 3 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_PrkA PF08298.11 AIN97887.1 - 0.013 14.5 0.1 0.057 12.3 0.0 2.0 3 0 0 3 3 2 0 PrkA AAA domain DUF815 PF05673.13 AIN97887.1 - 0.014 14.6 0.1 0.31 10.2 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF815) Zeta_toxin PF06414.12 AIN97887.1 - 0.021 14.1 0.0 0.54 9.5 0.0 3.2 3 0 0 3 3 3 0 Zeta toxin ATP_bind_1 PF03029.17 AIN97887.1 - 0.027 14.3 0.2 2.5 7.8 0.0 3.6 3 0 0 3 3 2 0 Conserved hypothetical ATP binding protein Nucleo_P87 PF07267.11 AIN97887.1 - 0.03 13.2 0.7 0.061 12.2 0.7 1.4 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 SRPRB PF09439.10 AIN97887.1 - 0.033 13.6 4.2 0.12 11.8 0.0 3.1 3 0 0 3 3 2 0 Signal recognition particle receptor beta subunit Guanylate_kin PF00625.21 AIN97887.1 - 0.038 13.7 9.5 0.19 11.4 0.0 4.3 5 0 0 5 5 3 0 Guanylate kinase Septin PF00735.18 AIN97887.1 - 0.06 12.6 0.3 13 5.0 0.0 2.9 3 0 0 3 3 2 0 Septin MMR_HSR1 PF01926.23 AIN97887.1 - 0.13 12.3 0.3 9.7 6.3 0.1 3.1 2 0 0 2 2 2 0 50S ribosome-binding GTPase SMC_N PF02463.19 AIN97887.1 - 0.18 11.2 0.0 5.2 6.4 0.0 2.9 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain G-alpha PF00503.20 AIN97887.1 - 0.26 10.4 1.9 1.1 8.4 0.0 2.8 3 0 0 3 3 3 0 G-protein alpha subunit ATPase_2 PF01637.18 AIN97887.1 - 0.33 10.8 0.0 0.33 10.8 0.0 4.3 5 0 0 5 5 2 0 ATPase domain predominantly from Archaea Glutaredoxin2_C PF04399.13 AIN97887.1 - 0.38 10.6 7.0 0.88 9.4 0.9 4.0 3 0 0 3 3 3 0 Glutaredoxin 2, C terminal domain MeaB PF03308.16 AIN97887.1 - 0.44 9.5 4.5 0.18 10.8 0.0 2.6 3 0 0 3 3 3 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Cytidylate_kin PF02224.18 AIN97887.1 - 3.5 7.3 5.7 7.6 6.2 0.0 3.3 3 0 0 3 3 3 0 Cytidylate kinase zf-CCHC_3 PF13917.6 AIN97888.1 - 2.9e-15 55.9 3.2 2.9e-15 55.9 3.2 1.9 2 1 0 2 2 2 1 Zinc knuckle eIF3g PF12353.8 AIN97888.1 - 0.00091 19.6 3.6 0.0011 19.4 1.0 2.1 2 0 0 2 2 2 1 Eukaryotic translation initiation factor 3 subunit G zf-CCHC PF00098.23 AIN97888.1 - 0.074 13.2 1.0 0.12 12.5 1.0 1.4 1 0 0 1 1 1 0 Zinc knuckle Fam20C PF06702.12 AIN97889.1 - 2.2e-06 27.6 0.0 0.012 15.4 0.0 2.3 2 0 0 2 2 2 2 Golgi casein kinase, C-terminal, Fam20 Metallophos PF00149.28 AIN97890.1 - 2.5e-33 116.3 0.0 3.4e-33 115.9 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Complex1_LYR PF05347.15 AIN97893.1 - 0.032 14.3 0.1 0.073 13.1 0.1 1.6 1 0 0 1 1 1 0 Complex 1 protein (LYR family) Robl_LC7 PF03259.17 AIN97894.1 - 0.0033 17.2 0.0 0.0044 16.8 0.0 1.4 1 1 0 1 1 1 1 Roadblock/LC7 domain BRCT PF00533.26 AIN97895.1 - 1.2e-07 31.9 0.0 3.4e-06 27.4 0.0 2.7 3 0 0 3 3 3 1 BRCA1 C Terminus (BRCT) domain FHA PF00498.26 AIN97895.1 - 3.4e-07 30.5 0.0 7.2e-07 29.5 0.0 1.6 1 0 0 1 1 1 1 FHA domain PTCB-BRCT PF12738.7 AIN97895.1 - 0.0006 19.7 0.0 0.0013 18.6 0.0 1.6 1 0 0 1 1 1 1 twin BRCT domain RTT107_BRCT_5 PF16770.5 AIN97895.1 - 0.0015 18.4 0.0 0.0025 17.6 0.0 1.3 1 0 0 1 1 1 1 Regulator of Ty1 transposition protein 107 BRCT domain BRCT_2 PF16589.5 AIN97895.1 - 0.0016 18.8 0.0 0.12 12.8 0.0 2.4 2 0 0 2 2 2 1 BRCT domain, a BRCA1 C-terminus domain Kinesin PF00225.23 AIN97897.1 - 7.7e-104 347.2 0.3 7.7e-104 347.2 0.3 1.7 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 AIN97897.1 - 1.3e-19 70.6 0.0 3e-19 69.4 0.0 1.7 1 0 0 1 1 1 1 Microtubule binding Pex24p PF06398.11 AIN97897.1 - 4.3e-07 29.3 0.2 4.3e-07 29.3 0.2 1.7 2 0 0 2 2 2 1 Integral peroxisomal membrane peroxin DUF1495 PF07381.11 AIN97897.1 - 0.037 13.8 0.0 0.18 11.7 0.0 2.1 2 0 0 2 2 2 0 Winged helix DNA-binding domain (DUF1495) SirA PF10747.9 AIN97897.1 - 0.091 13.1 0.5 0.34 11.2 0.5 1.9 1 0 0 1 1 1 0 Sporulation inhibitor of replication protein SirA Spc7 PF08317.11 AIN97897.1 - 6.8 5.5 26.5 5.5 5.8 13.5 1.7 1 1 1 2 2 2 0 Spc7 kinetochore protein Exonuc_VII_L PF02601.15 AIN97897.1 - 9.3 5.7 14.2 24 4.4 14.2 1.8 1 0 0 1 1 1 0 Exonuclease VII, large subunit Cullin_binding PF03556.15 AIN97898.1 - 2.4e-15 57.0 0.8 3.7e-15 56.4 0.8 1.3 1 0 0 1 1 1 1 Cullin binding Gar1 PF04410.14 AIN97899.1 - 6.1e-27 94.3 0.0 7.9e-27 93.9 0.0 1.0 1 0 0 1 1 1 1 Gar1/Naf1 RNA binding region DHHC PF01529.20 AIN97900.1 - 3.1e-15 56.4 6.8 3.1e-15 56.4 6.8 1.8 2 0 0 2 2 2 1 DHHC palmitoyltransferase YccF PF03733.13 AIN97900.1 - 0.14 12.9 0.7 0.14 12.9 0.7 3.6 4 0 0 4 4 4 0 Inner membrane component domain Prominin PF05478.11 AIN97900.1 - 0.26 9.2 3.2 3.7 5.4 3.8 2.0 2 0 0 2 2 2 0 Prominin Coatomer_WDAD PF04053.14 AIN97901.1 - 9.6e-95 318.2 0.0 1.4e-94 317.7 0.0 1.2 1 0 0 1 1 1 1 Coatomer WD associated region COPI_C PF06957.11 AIN97901.1 - 2.2e-94 316.5 0.0 3.4e-94 315.9 0.0 1.2 1 0 0 1 1 1 1 Coatomer (COPI) alpha subunit C-terminus WD40 PF00400.32 AIN97901.1 - 1.4e-39 133.3 23.7 3.6e-07 30.8 0.2 7.6 7 0 0 7 7 7 6 WD domain, G-beta repeat TPR_2 PF07719.17 AIN97901.1 - 0.031 14.4 0.3 8.2 6.8 0.0 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat Nucleoporin_N PF08801.11 AIN97901.1 - 0.2 10.4 1.6 0.44 9.2 0.0 2.3 3 0 0 3 3 3 0 Nup133 N terminal like TPR_14 PF13428.6 AIN97901.1 - 0.82 10.7 4.8 33 5.7 0.5 4.1 4 1 0 4 4 4 0 Tetratricopeptide repeat ESSS PF10183.9 AIN97902.1 - 1.5e-16 60.5 8.2 3e-16 59.5 8.2 1.6 1 1 0 1 1 1 1 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) Proteasome PF00227.26 AIN97903.1 - 1.3e-30 106.3 0.0 1.5e-30 106.1 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit ESSS PF10183.9 AIN97904.1 - 1.5e-16 60.5 8.2 3e-16 59.5 8.2 1.6 1 1 0 1 1 1 1 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) adh_short PF00106.25 AIN97905.1 - 6.3e-10 38.8 2.0 3.5e-09 36.4 2.0 1.9 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 AIN97905.1 - 8.9e-05 22.1 2.9 0.00035 20.2 2.9 1.8 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 AIN97905.1 - 0.00095 18.7 0.1 0.002 17.6 0.1 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family PI3_PI4_kinase PF00454.27 AIN97906.1 - 2.4e-58 197.9 0.1 5.5e-58 196.7 0.1 1.7 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FAT PF02259.23 AIN97906.1 - 8.5e-40 137.0 0.4 1.7e-39 136.0 0.4 1.6 1 0 0 1 1 1 1 FAT domain FRB_dom PF08771.11 AIN97906.1 - 5e-29 100.6 0.3 2e-28 98.7 0.3 2.2 1 0 0 1 1 1 1 FKBP12-rapamycin binding domain DUF3385 PF11865.8 AIN97906.1 - 8.9e-16 58.2 0.0 9.3e-15 54.9 0.0 2.8 3 0 0 3 3 3 1 Domain of unknown function (DUF3385) FATC PF02260.20 AIN97906.1 - 5.8e-11 42.0 0.3 2e-10 40.3 0.3 2.0 1 0 0 1 1 1 1 FATC domain HEAT PF02985.22 AIN97906.1 - 0.00023 21.2 3.7 7.7 7.1 0.0 7.1 6 0 0 6 6 6 1 HEAT repeat Cnd1 PF12717.7 AIN97906.1 - 0.0012 18.9 0.3 1.4 8.9 0.0 4.7 5 0 0 5 5 5 1 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 AIN97906.1 - 0.044 14.3 0.5 11 6.6 0.0 5.1 6 1 0 7 7 7 0 HEAT-like repeat Vac14_Fab1_bd PF12755.7 AIN97906.1 - 0.37 11.4 1.9 14 6.4 0.0 4.1 4 0 0 4 4 4 0 Vacuolar 14 Fab1-binding region ADIP PF11559.8 AIN97907.1 - 0.00019 21.6 5.8 0.00022 21.3 5.8 1.1 1 0 0 1 1 1 1 Afadin- and alpha -actinin-Binding Tom22 PF04281.13 AIN97907.1 - 0.00029 20.7 2.0 0.00034 20.4 2.0 1.1 1 0 0 1 1 1 1 Mitochondrial import receptor subunit Tom22 IFT57 PF10498.9 AIN97907.1 - 0.002 17.2 3.6 0.002 17.2 3.6 1.1 1 0 0 1 1 1 1 Intra-flagellar transport protein 57 DUF3450 PF11932.8 AIN97907.1 - 0.0022 17.4 6.0 0.0022 17.4 6.0 1.4 1 1 1 2 2 2 1 Protein of unknown function (DUF3450) BRE1 PF08647.11 AIN97907.1 - 0.0058 16.7 7.3 0.013 15.6 7.3 1.6 1 1 0 1 1 1 1 BRE1 E3 ubiquitin ligase HMMR_C PF15908.5 AIN97907.1 - 0.01 16.1 2.4 0.018 15.3 2.4 1.6 1 1 0 1 1 1 0 Hyaluronan mediated motility receptor C-terminal GAS PF13851.6 AIN97907.1 - 0.013 14.9 7.7 0.016 14.6 7.7 1.2 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding Lebercilin PF15619.6 AIN97907.1 - 0.015 15.0 8.9 0.037 13.7 8.9 1.6 1 1 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease DUF4061 PF13270.6 AIN97907.1 - 0.024 14.9 2.1 0.22 11.9 0.2 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4061) DUF1241 PF06840.11 AIN97907.1 - 0.025 14.2 3.3 0.033 13.8 3.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1241) Leu_zip PF15294.6 AIN97907.1 - 0.027 14.0 6.3 0.03 13.8 6.3 1.0 1 0 0 1 1 1 0 Leucine zipper DUF4795 PF16043.5 AIN97907.1 - 0.033 13.8 4.2 0.041 13.5 4.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4795) FUSC PF04632.12 AIN97907.1 - 0.043 12.3 1.9 0.049 12.2 1.9 1.0 1 0 0 1 1 1 0 Fusaric acid resistance protein family FAM76 PF16046.5 AIN97907.1 - 0.044 13.2 3.6 0.051 12.9 3.6 1.1 1 0 0 1 1 1 0 FAM76 protein Wtap PF17098.5 AIN97907.1 - 0.055 13.4 5.9 0.074 13.0 5.9 1.1 1 0 0 1 1 1 0 WTAP/Mum2p family Spc7 PF08317.11 AIN97907.1 - 0.087 11.7 8.5 0.11 11.3 8.5 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein JAKMIP_CC3 PF16034.5 AIN97907.1 - 0.089 12.7 6.1 0.23 11.4 6.1 1.7 1 1 0 1 1 1 0 JAKMIP CC3 domain DUF948 PF06103.11 AIN97907.1 - 0.11 12.8 0.9 4.4 7.6 0.3 2.1 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) FliD_N PF02465.18 AIN97907.1 - 0.11 13.3 4.2 0.19 12.5 4.2 1.5 1 1 0 1 1 1 0 Flagellar hook-associated protein 2 N-terminus DUF1664 PF07889.12 AIN97907.1 - 0.12 12.5 3.0 0.13 12.3 2.2 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) GCK PF07802.11 AIN97907.1 - 0.12 12.8 0.2 2.4 8.6 0.1 2.0 1 1 1 2 2 2 0 GCK domain Sec20 PF03908.13 AIN97907.1 - 0.13 12.2 2.0 0.34 10.9 0.6 2.0 1 1 1 2 2 2 0 Sec20 USP8_interact PF08941.10 AIN97907.1 - 0.14 12.0 1.4 0.16 11.8 1.4 1.2 1 0 0 1 1 1 0 USP8 interacting YabA PF06156.13 AIN97907.1 - 0.15 12.8 2.3 0.16 12.6 1.6 1.4 1 1 0 1 1 1 0 Initiation control protein YabA ABC_tran_CTD PF16326.5 AIN97907.1 - 0.2 11.9 10.0 0.095 13.0 5.2 2.4 1 1 1 2 2 2 0 ABC transporter C-terminal domain ERM PF00769.19 AIN97907.1 - 0.21 11.3 11.1 0.23 11.3 11.1 1.0 1 0 0 1 1 1 0 Ezrin/radixin/moesin family Prefoldin_2 PF01920.20 AIN97907.1 - 0.23 11.4 8.4 0.11 12.5 3.7 2.2 1 1 1 2 2 2 0 Prefoldin subunit Fib_alpha PF08702.10 AIN97907.1 - 0.49 10.6 3.5 1.2 9.3 0.4 1.8 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family FapA PF03961.13 AIN97907.1 - 0.57 8.7 4.4 0.86 8.1 4.4 1.4 1 1 0 1 1 1 0 Flagellar Assembly Protein A DivIC PF04977.15 AIN97907.1 - 0.77 9.6 10.0 2.6 7.9 0.3 2.8 1 1 2 3 3 3 0 Septum formation initiator APG6_N PF17675.1 AIN97907.1 - 0.89 10.1 11.8 6.2 7.4 11.8 2.0 1 1 0 1 1 1 0 Apg6 coiled-coil region ZapB PF06005.12 AIN97907.1 - 1.7 9.2 8.9 15 6.1 8.9 2.3 1 1 0 1 1 1 0 Cell division protein ZapB Bap31_Bap29_C PF18035.1 AIN97907.1 - 3.5 7.7 10.2 5.9 7.0 1.1 2.5 2 1 0 2 2 2 0 Bap31/Bap29 cytoplasmic coiled-coil domain DUF4140 PF13600.6 AIN97907.1 - 3.7 8.1 9.1 9.4 6.8 4.7 2.2 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) Rcd1 PF04078.13 AIN97908.1 - 4e-99 331.1 1.1 4.7e-99 330.9 1.1 1.0 1 0 0 1 1 1 1 Cell differentiation family, Rcd1-like RRM_1 PF00076.22 AIN97909.1 - 3.2e-29 100.5 0.0 5.1e-14 51.9 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 AIN97909.1 - 0.00027 21.0 0.0 0.33 11.1 0.0 3.4 3 1 0 3 3 3 2 RNA recognition motif RRM_3 PF08777.11 AIN97909.1 - 0.00041 20.3 0.0 2.3 8.3 0.0 3.2 3 0 0 3 3 3 2 RNA binding motif RNA_bind PF08675.11 AIN97909.1 - 0.0061 16.6 0.1 0.62 10.1 0.0 3.0 3 1 0 3 3 3 1 RNA binding domain Nup35_RRM_2 PF14605.6 AIN97909.1 - 0.038 14.0 0.0 0.24 11.4 0.0 2.2 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif RRM_5 PF13893.6 AIN97909.1 - 0.1 12.2 0.0 11 5.6 0.0 2.6 2 1 1 3 3 3 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PHM7_cyt PF14703.6 AIN97909.1 - 0.14 12.4 2.3 7.9 6.7 0.3 3.2 2 2 2 4 4 4 0 Cytosolic domain of 10TM putative phosphate transporter Tmemb_170 PF10190.9 AIN97910.1 - 0.03 14.7 9.1 0.039 14.3 9.1 1.1 1 0 0 1 1 1 0 Putative transmembrane protein 170 FAM176 PF14851.6 AIN97910.1 - 0.039 13.6 0.9 0.059 13.0 0.9 1.3 1 0 0 1 1 1 0 FAM176 family DUF308 PF03729.13 AIN97910.1 - 0.04 14.3 8.4 1.6 9.1 5.2 2.4 1 1 1 2 2 2 0 Short repeat of unknown function (DUF308) YpmT PF17431.2 AIN97910.1 - 1.8 8.6 8.7 0.91 9.6 3.6 2.3 2 0 0 2 2 2 0 Uncharacterized YmpT-like Tetraspanin PF00335.20 AIN97910.1 - 4 7.1 12.7 2.4 7.8 11.3 1.3 1 1 0 1 1 1 0 Tetraspanin family WD40 PF00400.32 AIN97911.1 - 4.6e-05 24.1 2.6 0.19 12.7 0.0 4.8 5 0 0 5 5 5 2 WD domain, G-beta repeat ARD PF03079.14 AIN97913.1 - 1.7e-26 93.3 0.0 1.7e-26 93.3 0.0 2.1 2 0 0 2 2 2 1 ARD/ARD' family Cupin_2 PF07883.11 AIN97913.1 - 5.2e-07 29.3 0.0 1.9e-06 27.5 0.0 1.8 2 0 0 2 2 2 1 Cupin domain AraC_binding PF02311.19 AIN97913.1 - 0.00019 21.4 0.0 0.00034 20.5 0.0 1.4 1 0 0 1 1 1 1 AraC-like ligand binding domain Cupin_3 PF05899.12 AIN97913.1 - 0.00038 20.1 0.0 0.00096 18.8 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF861) Cupin_8 PF13621.6 AIN97913.1 - 0.03 14.0 1.6 0.067 12.9 0.0 2.0 2 1 0 2 2 2 0 Cupin-like domain Cupin_6 PF12852.7 AIN97913.1 - 0.035 13.8 0.0 0.054 13.2 0.0 1.3 1 0 0 1 1 1 0 Cupin UN_NPL4 PF11543.8 AIN97913.1 - 0.092 13.2 0.0 0.26 11.8 0.0 1.9 2 0 0 2 2 2 0 Nuclear pore localisation protein NPL4 2OG-FeII_Oxy_5 PF13759.6 AIN97913.1 - 0.15 12.5 0.3 0.41 11.1 0.0 1.9 2 0 0 2 2 2 0 Putative 2OG-Fe(II) oxygenase Cupin_1 PF00190.22 AIN97913.1 - 0.18 11.4 0.0 0.34 10.5 0.0 1.4 1 0 0 1 1 1 0 Cupin CDC45 PF02724.14 AIN97913.1 - 0.51 8.6 5.3 0.51 8.6 5.3 1.1 1 0 0 1 1 1 0 CDC45-like protein PutA_N PF18083.1 AIN97914.1 - 0.078 13.0 1.4 0.45 10.5 0.4 2.6 2 0 0 2 2 2 0 Proline utilization A N-terminal domain cNMP_binding PF00027.29 AIN97915.1 - 4.1e-08 33.2 0.1 1.5e-07 31.4 0.0 2.0 2 0 0 2 2 2 1 Cyclic nucleotide-binding domain RNA_pol_Rpb2_6 PF00562.28 AIN97916.1 - 1.3e-116 390.0 0.0 2.2e-116 389.1 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 AIN97916.1 - 6.4e-45 153.2 0.8 9.2e-45 152.7 0.8 1.2 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_7 PF04560.20 AIN97916.1 - 6e-32 109.9 0.2 2.1e-31 108.2 0.2 2.0 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_2 PF04561.14 AIN97916.1 - 8.5e-21 74.4 0.1 1.8e-20 73.4 0.1 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_4 PF04566.13 AIN97916.1 - 2.8e-19 69.1 1.8 2.8e-19 69.1 1.8 2.0 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_3 PF04565.16 AIN97916.1 - 7.6e-19 67.7 0.0 1.5e-18 66.7 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_5 PF04567.17 AIN97916.1 - 3.7e-08 33.8 0.3 1.3e-07 32.1 0.3 2.0 1 1 0 1 1 1 1 RNA polymerase Rpb2, domain 5 WD40 PF00400.32 AIN97917.1 - 5.9e-19 68.1 7.2 3.1e-05 24.6 0.1 4.7 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 AIN97917.1 - 0.00013 22.2 0.0 0.35 11.2 0.0 3.0 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 AIN97917.1 - 0.0025 16.6 1.8 0.25 10.0 0.2 2.8 1 1 2 3 3 3 2 Nucleoporin Nup120/160 DUF1500 PF07389.12 AIN97917.1 - 0.15 12.2 0.0 0.36 10.9 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1500) Hira PF07569.11 AIN97917.1 - 0.28 10.9 3.3 10 5.8 0.2 3.1 2 1 1 3 3 3 0 TUP1-like enhancer of split DOT1 PF08123.13 AIN97918.1 - 2.3e-19 69.7 0.0 3.5e-19 69.2 0.0 1.1 1 0 0 1 1 1 1 Histone methylation protein DOT1 Methyltransf_25 PF13649.6 AIN97918.1 - 2.4e-05 24.9 0.0 4.4e-05 24.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 AIN97918.1 - 2.8e-05 24.7 0.0 7e-05 23.4 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 AIN97918.1 - 6.5e-05 22.8 0.0 9.6e-05 22.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 AIN97918.1 - 0.0071 16.2 0.0 0.0087 15.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.6 AIN97918.1 - 0.017 15.1 0.0 0.043 13.8 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_12 PF08242.12 AIN97918.1 - 0.023 15.4 0.0 0.04 14.7 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain CMAS PF02353.20 AIN97918.1 - 0.077 12.3 0.0 0.12 11.7 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase AdoMet_MTase PF07757.13 AIN97918.1 - 0.081 13.3 0.0 0.16 12.4 0.0 1.5 1 0 0 1 1 1 0 Predicted AdoMet-dependent methyltransferase ADH_zinc_N PF00107.26 AIN97918.1 - 0.1 12.6 0.0 0.17 11.9 0.0 1.3 1 0 0 1 1 1 0 Zinc-binding dehydrogenase PHO4 PF01384.20 AIN97919.1 - 8.8e-109 363.6 19.2 1.1e-108 363.3 19.2 1.1 1 0 0 1 1 1 1 Phosphate transporter family DUF5520 PF17658.1 AIN97920.1 - 0.022 13.9 0.2 0.031 13.4 0.2 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5520) ASF1_hist_chap PF04729.13 AIN97921.1 - 3.1e-46 157.1 0.0 3.8e-46 156.8 0.0 1.0 1 0 0 1 1 1 1 ASF1 like histone chaperone BRCA-2_OB1 PF09103.10 AIN97922.1 - 1.5e-24 86.3 0.0 2.5e-24 85.6 0.0 1.4 1 0 0 1 1 1 1 BRCA2, oligonucleotide/oligosaccharide-binding, domain 1 BRCA2 PF00634.18 AIN97922.1 - 6.4e-05 22.5 0.1 0.0002 21.0 0.0 1.8 2 0 0 2 2 2 1 BRCA2 repeat DUF5521 PF17659.1 AIN97922.1 - 0.11 10.3 0.0 0.17 9.7 0.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5521) zf-RanBP PF00641.18 AIN97922.1 - 9.8 5.6 7.4 1.3 8.4 2.4 2.2 2 0 0 2 2 2 0 Zn-finger in Ran binding protein and others MRG PF05712.13 AIN97923.1 - 0.012 14.9 0.0 0.013 14.9 0.0 1.1 1 0 0 1 1 1 0 MRG Ion_trans_2 PF07885.16 AIN97925.1 - 4.6e-12 45.7 6.5 4.6e-12 45.7 6.5 2.6 3 0 0 3 3 3 1 Ion channel BK_channel_a PF03493.18 AIN97925.1 - 1.7e-09 37.7 0.0 5.6e-09 36.1 0.0 1.9 1 0 0 1 1 1 1 Calcium-activated BK potassium channel alpha subunit PGK PF00162.19 AIN97926.1 - 6.8e-156 519.0 0.0 7.9e-156 518.7 0.0 1.0 1 0 0 1 1 1 1 Phosphoglycerate kinase NB-ARC PF00931.22 AIN97927.1 - 3.2e-07 29.8 0.1 0.015 14.5 0.0 2.2 1 1 1 2 2 2 2 NB-ARC domain AAA_16 PF13191.6 AIN97927.1 - 1.5e-05 25.4 0.3 0.00022 21.6 0.3 2.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_14 PF13173.6 AIN97927.1 - 0.027 14.5 0.0 0.1 12.6 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 AIN97927.1 - 0.061 12.8 0.0 0.12 11.9 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region NACHT PF05729.12 AIN97927.1 - 0.083 12.8 0.1 0.97 9.3 0.0 2.2 1 1 1 2 2 2 0 NACHT domain MORN PF02493.20 AIN97928.1 - 1.7e-10 40.2 15.1 1.8e-06 27.5 0.0 6.6 6 0 0 6 6 6 3 MORN repeat Ferritin_2 PF13668.6 AIN97929.1 - 0.14 12.4 0.0 0.32 11.2 0.0 1.5 1 0 0 1 1 1 0 Ferritin-like domain DUF1736 PF08409.11 AIN97930.1 - 1.7e-18 66.4 1.0 3.8e-18 65.2 0.2 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF1736) CBM32 PF18344.1 AIN97931.1 - 0.023 14.6 0.2 0.048 13.5 0.2 1.5 1 0 0 1 1 1 0 Carbohydrate binding module family 32 NifW PF03206.14 AIN97931.1 - 0.056 14.0 3.1 0.14 12.7 0.1 2.4 2 0 0 2 2 2 0 Nitrogen fixation protein NifW Peptidase_S46 PF10459.9 AIN97931.1 - 0.06 12.0 12.1 0.083 11.5 12.1 1.1 1 0 0 1 1 1 0 Peptidase S46 Sec20 PF03908.13 AIN97931.1 - 0.11 12.5 5.2 0.21 11.5 4.1 2.2 1 1 1 2 2 2 0 Sec20 TMF_TATA_bd PF12325.8 AIN97931.1 - 0.13 12.5 18.5 0.13 12.4 5.4 3.0 3 0 0 3 3 3 0 TATA element modulatory factor 1 TATA binding Spc7 PF08317.11 AIN97931.1 - 0.17 10.7 13.7 0.12 11.2 11.9 1.7 1 1 0 1 1 1 0 Spc7 kinetochore protein PKcGMP_CC PF16808.5 AIN97931.1 - 0.2 11.5 2.3 31 4.5 0.0 3.7 3 0 0 3 3 3 0 Coiled-coil N-terminus of cGMP-dependent protein kinase DUF2408 PF10303.9 AIN97931.1 - 0.47 11.0 11.5 1 10.0 2.5 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF2408) RILP PF11461.8 AIN97931.1 - 0.67 10.2 5.1 1.9 8.8 4.0 2.2 1 1 1 2 2 2 0 Rab interacting lysosomal protein DUF948 PF06103.11 AIN97931.1 - 1.1 9.6 7.2 0.45 10.8 1.7 3.0 1 1 2 3 3 3 0 Bacterial protein of unknown function (DUF948) Mto2_bdg PF12808.7 AIN97931.1 - 1.3 9.3 6.8 0.28 11.5 0.3 2.8 3 0 0 3 3 2 0 Micro-tubular organiser Mto1 C-term Mto2-binding region DUF641 PF04859.12 AIN97931.1 - 1.4 9.2 9.0 0.98 9.8 5.0 2.5 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) DUF16 PF01519.16 AIN97931.1 - 2.4 8.7 8.4 4.8 7.7 0.3 2.9 2 1 1 3 3 2 0 Protein of unknown function DUF16 GAS PF13851.6 AIN97931.1 - 3.8 6.8 12.0 9.4 5.5 11.8 1.7 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding CENP-Q PF13094.6 AIN97931.1 - 4 7.6 17.1 48 4.1 16.4 2.9 2 1 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit Kelch_6 PF13964.6 AIN97936.1 - 1e-25 89.1 6.9 4.3e-06 26.8 0.1 5.8 6 0 0 6 6 6 5 Kelch motif Kelch_3 PF13415.6 AIN97936.1 - 6e-22 77.4 10.3 0.00033 20.9 0.0 7.0 7 0 0 7 7 7 4 Galactose oxidase, central domain Kelch_1 PF01344.25 AIN97936.1 - 1.2e-19 69.6 20.2 1.1e-05 24.9 0.4 6.2 7 0 0 7 7 7 5 Kelch motif Kelch_5 PF13854.6 AIN97936.1 - 2.7e-19 68.7 11.2 3.4e-06 26.9 0.0 5.1 5 0 0 5 5 5 4 Kelch motif Kelch_4 PF13418.6 AIN97936.1 - 1.1e-17 63.8 1.9 1.1e-05 25.3 0.0 5.5 5 0 0 5 5 5 4 Galactose oxidase, central domain Kelch_2 PF07646.15 AIN97936.1 - 4.6e-14 51.7 17.3 0.0009 19.1 0.2 6.7 6 1 0 6 6 6 5 Kelch motif HTH_26 PF13443.6 AIN97937.1 - 0.09 13.2 0.2 19 5.8 0.1 2.9 2 0 0 2 2 2 0 Cro/C1-type HTH DNA-binding domain PilX_N PF14341.6 AIN97939.1 - 0.17 11.9 0.5 0.43 10.6 0.5 1.7 1 0 0 1 1 1 0 PilX N-terminal DS PF01916.17 AIN97940.1 - 3.4e-86 289.1 0.0 4.2e-86 288.8 0.0 1.1 1 0 0 1 1 1 1 Deoxyhypusine synthase AAA_5 PF07728.14 AIN97941.1 - 4.5e-122 402.5 0.0 4.7e-22 78.5 0.0 8.9 6 2 1 8 8 8 8 AAA domain (dynein-related subfamily) AAA_lid_7 PF17867.1 AIN97941.1 - 1.3e-43 147.5 3.2 2.1e-13 50.4 0.1 5.5 5 0 0 5 5 4 4 Midasin AAA lid domain AAA_3 PF07726.11 AIN97941.1 - 1.3e-25 89.7 0.0 0.0047 16.8 0.0 8.5 8 0 0 8 8 8 4 ATPase family associated with various cellular activities (AAA) AAA_6 PF12774.7 AIN97941.1 - 5.1e-25 88.1 1.6 0.0018 17.3 0.0 8.5 8 1 0 8 8 8 5 Hydrolytic ATP binding site of dynein motor region AAA_7 PF12775.7 AIN97941.1 - 1.4e-23 83.4 0.6 0.00068 19.2 0.0 6.5 6 0 0 6 6 6 6 P-loop containing dynein motor region AAA_16 PF13191.6 AIN97941.1 - 1.3e-22 81.0 12.1 0.00042 20.7 0.0 9.6 8 1 0 8 8 7 5 AAA ATPase domain AAA_lid_5 PF17865.1 AIN97941.1 - 2.5e-21 75.7 0.0 2.6e-20 72.5 0.0 2.7 3 0 0 3 3 2 1 Midasin AAA lid domain AAA PF00004.29 AIN97941.1 - 2.9e-20 73.1 2.4 0.00086 19.7 0.0 7.2 6 1 0 6 6 6 4 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 AIN97941.1 - 6.4e-20 71.8 0.1 0.021 15.1 0.0 7.4 6 0 0 6 6 6 4 AAA domain Dynein_heavy PF03028.15 AIN97941.1 - 1.3e-16 60.7 0.0 0.034 14.2 0.0 5.9 5 0 0 5 5 5 4 Dynein heavy chain region D6 P-loop domain AAA_30 PF13604.6 AIN97941.1 - 4e-16 59.3 0.0 0.014 15.2 0.0 7.7 7 0 0 7 7 7 3 AAA domain Sigma54_activat PF00158.26 AIN97941.1 - 1.1e-15 57.8 0.0 0.022 14.5 0.0 6.5 6 0 0 6 6 6 3 Sigma-54 interaction domain TsaE PF02367.17 AIN97941.1 - 1.1e-12 48.0 4.4 0.015 15.3 0.0 6.5 6 0 0 6 6 6 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_14 PF13173.6 AIN97941.1 - 2.1e-12 47.2 0.0 0.025 14.6 0.0 6.2 5 1 0 5 5 5 2 AAA domain Sigma54_activ_2 PF14532.6 AIN97941.1 - 1.8e-11 44.3 0.2 0.0016 18.5 0.0 6.0 6 0 0 6 6 6 2 Sigma-54 interaction domain AAA_18 PF13238.6 AIN97941.1 - 1.4e-09 38.6 1.1 1.2 9.7 0.0 7.0 6 1 0 6 6 5 3 AAA domain Zeta_toxin PF06414.12 AIN97941.1 - 3.3e-09 36.3 0.2 0.2 10.9 0.0 5.8 6 0 0 6 6 6 2 Zeta toxin AAA_29 PF13555.6 AIN97941.1 - 5e-09 35.8 1.4 14 5.5 0.0 6.6 6 0 0 6 6 6 0 P-loop containing region of AAA domain IstB_IS21 PF01695.17 AIN97941.1 - 1.8e-08 34.3 0.2 0.16 11.7 0.0 4.6 5 0 0 5 5 4 2 IstB-like ATP binding protein T2SSE PF00437.20 AIN97941.1 - 2.5e-08 33.3 2.1 0.29 10.1 0.0 5.8 6 0 0 6 6 6 2 Type II/IV secretion system protein RsgA_GTPase PF03193.16 AIN97941.1 - 5.2e-08 33.0 1.1 1.3 8.9 0.0 5.5 5 0 0 5 5 5 2 RsgA GTPase Rad17 PF03215.15 AIN97941.1 - 7.3e-08 32.6 1.0 10 6.0 0.0 6.2 6 0 0 6 6 6 0 Rad17 P-loop domain RNA_helicase PF00910.22 AIN97941.1 - 4.1e-07 30.4 1.9 0.32 11.4 0.0 6.1 6 0 0 6 6 5 1 RNA helicase DUF815 PF05673.13 AIN97941.1 - 4.1e-07 29.4 3.2 0.19 10.9 0.0 5.0 6 0 0 6 6 5 2 Protein of unknown function (DUF815) AAA_25 PF13481.6 AIN97941.1 - 6.4e-07 29.1 6.5 1 8.9 0.0 6.5 7 0 0 7 7 5 1 AAA domain AAA_33 PF13671.6 AIN97941.1 - 2.3e-06 27.8 8.1 6.1 7.0 0.0 6.8 7 0 0 7 7 6 0 AAA domain Mg_chelatase PF01078.21 AIN97941.1 - 5.2e-06 26.0 2.4 21 4.4 0.0 7.3 9 0 0 9 9 7 0 Magnesium chelatase, subunit ChlI ABC_tran PF00005.27 AIN97941.1 - 5.7e-06 26.9 24.5 0.29 11.7 0.0 7.2 8 0 0 8 8 6 2 ABC transporter RuvB_N PF05496.12 AIN97941.1 - 3.1e-05 23.8 0.4 7.1 6.4 0.0 5.8 7 0 0 7 7 6 0 Holliday junction DNA helicase RuvB P-loop domain NACHT PF05729.12 AIN97941.1 - 0.00028 20.8 6.1 1 9.2 0.0 5.4 6 0 0 6 6 5 1 NACHT domain MeaB PF03308.16 AIN97941.1 - 0.0012 17.9 2.3 0.67 8.9 0.1 4.2 4 0 0 4 4 4 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_19 PF13245.6 AIN97941.1 - 0.0012 19.2 5.4 14 6.0 0.1 5.5 5 0 0 5 5 4 0 AAA domain CPT PF07931.12 AIN97941.1 - 0.0014 18.5 0.2 1.3 8.8 0.0 4.4 4 0 0 4 4 3 1 Chloramphenicol phosphotransferase-like protein AAA_8 PF12780.7 AIN97941.1 - 0.0017 17.8 0.0 6.2 6.1 0.0 4.2 4 0 0 4 4 4 0 P-loop containing dynein motor region D4 NTPase_1 PF03266.15 AIN97941.1 - 0.017 15.0 3.2 4.3 7.2 0.1 4.2 4 0 0 4 4 4 0 NTPase dNK PF01712.19 AIN97941.1 - 0.025 14.4 3.3 20 5.0 0.0 4.5 5 0 0 5 5 4 0 Deoxynucleoside kinase TniB PF05621.11 AIN97941.1 - 0.037 13.4 0.0 6.3 6.2 0.0 4.3 5 0 0 5 5 5 0 Bacterial TniB protein ATPase_2 PF01637.18 AIN97941.1 - 0.038 13.9 0.0 8.6 6.2 0.0 3.9 4 0 0 4 4 4 0 ATPase domain predominantly from Archaea TIP49 PF06068.13 AIN97941.1 - 0.043 13.0 0.3 4.5 6.4 0.1 3.4 3 0 0 3 3 3 0 TIP49 P-loop domain PduV-EutP PF10662.9 AIN97941.1 - 0.27 11.0 1.7 46 3.7 0.0 4.2 5 0 0 5 5 4 0 Ethanolamine utilisation - propanediol utilisation SRP54 PF00448.22 AIN97941.1 - 0.63 9.6 8.2 12 5.5 0.2 4.7 5 0 0 5 5 5 0 SRP54-type protein, GTPase domain PhoH PF02562.16 AIN97941.1 - 1.3 8.4 9.6 9.1 5.7 0.0 4.5 5 0 0 5 5 5 0 PhoH-like protein Roc PF08477.13 AIN97941.1 - 2.8 8.2 4.7 68 3.7 0.0 4.7 5 0 0 5 5 4 0 Ras of Complex, Roc, domain of DAPkinase DUF4154 PF13689.6 AIN97942.1 - 0.045 14.0 0.1 1.9 8.7 0.0 2.3 2 0 0 2 2 2 0 YfiR/HmsC-like Enkurin PF13864.6 AIN97943.1 - 5.3e-19 68.5 7.0 9.8e-19 67.6 7.0 1.5 1 0 0 1 1 1 1 Calmodulin-binding BCDHK_Adom3 PF10436.9 AIN97944.1 - 2.2e-18 66.6 0.1 3.7e-18 65.9 0.1 1.4 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.26 AIN97944.1 - 3.2e-10 40.5 0.0 7.8e-09 36.0 0.0 2.2 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 AIN97944.1 - 1.7e-05 24.7 0.0 3.7e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase ZZ PF00569.17 AIN97945.1 - 4.6e-07 29.5 7.5 4.6e-07 29.5 7.5 2.9 2 0 0 2 2 2 1 Zinc finger, ZZ type C1_1 PF00130.22 AIN97945.1 - 0.38 10.7 15.0 0.81 9.6 1.1 2.9 3 0 0 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zinc-ribbons_6 PF07191.12 AIN97945.1 - 5.4 7.1 12.7 1.3 9.1 3.4 2.7 2 0 0 2 2 2 0 zinc-ribbons LRR_6 PF13516.6 AIN97946.1 - 5.7e-05 22.8 2.0 0.23 11.6 0.0 4.1 5 0 0 5 5 5 2 Leucine Rich repeat LRR_4 PF12799.7 AIN97946.1 - 0.0088 16.4 1.3 6.5 7.3 0.0 3.7 3 1 0 3 3 3 1 Leucine Rich repeats (2 copies) LRR_4 PF12799.7 AIN97948.1 - 3.3e-13 49.6 19.3 2.7e-05 24.4 1.8 5.7 4 2 1 5 5 5 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 AIN97948.1 - 2.4e-11 43.2 14.7 5.2e-06 26.1 1.3 3.9 2 2 2 4 4 4 4 Leucine rich repeat LRR_1 PF00560.33 AIN97948.1 - 3.6e-06 26.8 13.5 0.74 10.6 0.4 7.2 6 1 1 7 7 7 2 Leucine Rich Repeat LRR_6 PF13516.6 AIN97948.1 - 0.00034 20.4 18.4 0.09 12.9 0.6 7.1 7 0 0 7 7 7 1 Leucine Rich repeat LRR_9 PF14580.6 AIN97948.1 - 0.086 12.3 2.0 3.2 7.2 0.0 2.9 2 1 1 3 3 3 0 Leucine-rich repeat DUF3729 PF12526.8 AIN97948.1 - 0.13 13.8 5.4 2.1 9.9 0.2 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3729) Acetyltransf_13 PF13880.6 AIN97951.1 - 3.3e-22 78.3 0.0 7.2e-22 77.2 0.0 1.6 1 0 0 1 1 1 1 ESCO1/2 acetyl-transferase Acetyltransf_7 PF13508.7 AIN97951.1 - 0.027 14.9 0.0 0.096 13.1 0.0 1.9 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain MFS_1 PF07690.16 AIN97952.1 - 2e-18 66.5 32.3 3.1e-12 46.1 11.5 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 AIN97952.1 - 0.016 14.1 34.3 0.076 11.9 11.0 3.2 2 1 1 3 3 3 0 Sugar (and other) transporter DUF4083 PF13314.6 AIN97952.1 - 5.8 6.9 4.7 3 7.8 0.2 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4083) DUF2946 PF11162.8 AIN97954.1 - 1.2e-12 48.5 0.0 2.4e-12 47.5 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2946) DUF4692 PF15763.5 AIN97954.1 - 0.071 13.6 0.0 0.13 12.8 0.0 1.4 1 0 0 1 1 1 0 Regulator of human erythroid cell expansion (RHEX) PRIMA1 PF16101.5 AIN97954.1 - 0.14 12.2 0.3 0.25 11.4 0.3 1.3 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 EphA2_TM PF14575.6 AIN97954.1 - 0.19 12.6 0.1 0.43 11.5 0.1 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DUF4006 PF13179.6 AIN97954.1 - 2.2 8.3 4.5 23 5.0 0.5 2.4 2 0 0 2 2 2 0 Family of unknown function (DUF4006) Metallophos PF00149.28 AIN97955.1 - 0.0083 16.6 0.1 0.037 14.5 0.1 2.1 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos PF00149.28 AIN97956.1 - 0.012 16.1 0.2 0.06 13.8 0.2 2.2 1 1 0 1 1 1 0 Calcineurin-like phosphoesterase Cellulase PF00150.18 AIN97956.1 - 0.098 12.1 0.0 0.16 11.4 0.0 1.2 1 0 0 1 1 1 0 Cellulase (glycosyl hydrolase family 5) EI24 PF07264.11 AIN97956.1 - 7.9 6.7 30.4 0.016 15.4 13.4 2.9 3 1 0 3 3 3 0 Etoposide-induced protein 2.4 (EI24) NUDIX PF00293.28 AIN97957.1 - 0.002 18.2 0.3 10 6.2 0.0 3.7 3 1 0 3 3 3 2 NUDIX domain Rad1 PF02144.16 AIN97958.1 - 6.7e-07 28.6 0.0 1.9e-06 27.2 0.0 1.6 1 1 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 Gp-FAR-1 PF05823.12 AIN97960.1 - 0.0012 19.3 8.6 0.0012 19.3 8.6 3.1 2 1 1 3 3 3 1 Nematode fatty acid retinoid binding protein (Gp-FAR-1) Methyltransf_8 PF05148.15 AIN97961.1 - 1.7e-53 181.7 0.0 2.3e-53 181.3 0.0 1.2 1 0 0 1 1 1 1 Hypothetical methyltransferase Methyltransf_11 PF08241.12 AIN97961.1 - 6e-07 30.0 0.1 1.1e-05 26.0 0.1 2.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 AIN97961.1 - 5.8e-05 23.7 0.0 0.024 15.3 0.0 2.8 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 AIN97961.1 - 0.0012 18.2 0.0 0.0033 16.8 0.0 1.7 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family IHABP4_N PF16174.5 AIN97961.1 - 0.52 10.9 8.3 0.91 10.1 8.3 1.3 1 0 0 1 1 1 0 Intracellular hyaluronan-binding protein 4 N-terminal DAO PF01266.24 AIN97962.1 - 3.7e-18 66.2 0.1 1.4e-15 57.8 0.1 3.8 1 1 0 1 1 1 1 FAD dependent oxidoreductase DAO_C PF16901.5 AIN97962.1 - 1.2e-10 41.4 0.1 5e-10 39.3 0.1 2.1 1 0 0 1 1 1 1 C-terminal domain of alpha-glycerophosphate oxidase FAD_oxidored PF12831.7 AIN97962.1 - 6e-08 32.5 0.1 9.5e-08 31.8 0.1 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 AIN97962.1 - 6.7e-07 28.7 0.1 1.2e-06 27.9 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 AIN97962.1 - 8.7e-06 25.9 0.4 2.3e-05 24.5 0.4 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.22 AIN97962.1 - 1.8e-05 24.0 0.0 3.1e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 Glucose inhibited division protein A HI0933_like PF03486.14 AIN97962.1 - 0.00036 19.3 0.3 0.00057 18.7 0.3 1.2 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_2 PF07992.14 AIN97962.1 - 0.00076 18.8 0.0 0.0014 18.0 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 AIN97962.1 - 0.069 12.2 0.3 0.15 11.1 0.3 1.5 1 0 0 1 1 1 0 Lycopene cyclase protein Pyr_redox PF00070.27 AIN97962.1 - 0.16 12.5 0.6 0.46 11.1 0.3 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase GGACT PF06094.12 AIN97963.1 - 2.5e-08 34.6 0.1 3e-05 24.6 0.2 3.1 2 2 0 2 2 2 2 Gamma-glutamyl cyclotransferase, AIG2-like AIG2_2 PF13772.6 AIN97963.1 - 2.1e-06 28.0 0.8 1.3e-05 25.4 0.1 2.6 3 0 0 3 3 3 1 AIG2-like family Tubulin PF00091.25 AIN97964.1 - 2e-27 96.7 0.3 4.6e-14 53.1 0.0 3.0 1 1 1 2 2 2 2 Tubulin/FtsZ family, GTPase domain Tubulin_2 PF13809.6 AIN97964.1 - 0.0012 18.1 0.0 0.002 17.4 0.0 1.2 1 0 0 1 1 1 1 Tubulin like PPR_2 PF13041.6 AIN97965.1 - 7.8e-09 35.6 0.1 0.04 14.1 0.0 4.6 3 1 2 5 5 5 3 PPR repeat family PPR PF01535.20 AIN97965.1 - 1.4e-06 28.1 0.0 3 8.3 0.0 4.4 5 0 0 5 5 5 3 PPR repeat PPR_3 PF13812.6 AIN97965.1 - 0.0028 17.7 0.1 0.021 14.9 0.0 2.3 3 0 0 3 3 3 1 Pentatricopeptide repeat domain PPR_long PF17177.4 AIN97965.1 - 0.0054 16.1 0.4 0.033 13.6 0.0 2.0 1 1 1 2 2 2 1 Pentacotripeptide-repeat region of PRORP DNA_RNApol_7kD PF03604.13 AIN97966.1 - 0.048 13.3 1.2 0.094 12.4 1.2 1.6 1 1 0 1 1 1 0 DNA directed RNA polymerase, 7 kDa subunit TF_Zn_Ribbon PF08271.12 AIN97966.1 - 0.061 12.9 0.8 0.84 9.2 0.1 2.2 2 0 0 2 2 2 0 TFIIB zinc-binding PhnA_Zn_Ribbon PF08274.12 AIN97966.1 - 0.095 12.7 0.6 5.8 6.9 0.0 2.2 2 0 0 2 2 2 0 PhnA Zinc-Ribbon CTP_transf_like PF01467.26 AIN97967.1 - 7.9e-06 26.1 0.0 4e-05 23.8 0.0 2.1 1 1 0 1 1 1 1 Cytidylyltransferase-like Ribosomal_S15 PF00312.22 AIN97968.1 - 2.9e-07 30.6 1.6 6.3e-07 29.5 1.6 1.5 1 0 0 1 1 1 1 Ribosomal protein S15 DUF4404 PF14357.6 AIN97968.1 - 0.028 15.0 1.0 0.59 10.8 0.0 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4404) MORN PF02493.20 AIN97969.1 - 1.8e-16 59.0 18.4 4.8e-05 23.0 0.1 7.4 9 0 0 9 9 9 4 MORN repeat WW PF00397.26 AIN97969.1 - 0.094 12.8 0.3 0.24 11.5 0.3 1.7 1 0 0 1 1 1 0 WW domain Herpes_UL25 PF01499.16 AIN97969.1 - 6.9 5.1 11.4 13 4.1 11.4 1.4 1 0 0 1 1 1 0 Herpesvirus UL25 family Endonuc_Holl PF10107.9 AIN97970.1 - 0.16 11.8 0.0 0.22 11.4 0.0 1.3 1 0 0 1 1 1 0 Endonuclease related to archaeal Holliday junction resolvase RWD PF05773.22 AIN97971.1 - 1.4e-08 35.0 0.6 2.3e-08 34.3 0.6 1.4 1 0 0 1 1 1 1 RWD domain DFRP_C PF16543.5 AIN97971.1 - 0.00018 21.9 0.6 0.00038 20.9 0.6 1.5 1 0 0 1 1 1 1 DRG Family Regulatory Proteins, Tma46 phage_tail_N PF08400.10 AIN97971.1 - 0.068 13.2 0.6 0.71 9.9 0.1 2.2 2 1 0 2 2 2 0 Prophage tail fibre N-terminal DnaJ_C PF01556.18 AIN97972.1 - 6e-17 62.1 0.0 9.2e-17 61.5 0.0 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.19 AIN97972.1 - 2e-09 37.7 10.1 4.2e-09 36.6 10.1 1.6 1 0 0 1 1 1 1 DnaJ central domain Anti-TRAP PF15777.5 AIN97972.1 - 0.00027 20.8 11.9 0.065 13.2 2.5 2.9 2 1 1 3 3 3 2 Tryptophan RNA-binding attenuator protein inhibitory protein Rhv PF00073.20 AIN97972.1 - 0.15 11.7 0.0 0.29 10.7 0.0 1.4 1 0 0 1 1 1 0 picornavirus capsid protein CTP_synth_N PF06418.14 AIN97973.1 - 2.7e-106 354.7 0.0 3.5e-106 354.4 0.0 1.1 1 0 0 1 1 1 1 CTP synthase N-terminus GATase PF00117.28 AIN97973.1 - 3.4e-45 154.1 0.0 1.4e-44 152.2 0.0 1.8 2 0 0 2 2 2 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 AIN97973.1 - 1.1e-07 31.9 0.1 9e-07 28.9 0.0 2.1 2 0 0 2 2 2 1 Peptidase C26 CbiA PF01656.23 AIN97973.1 - 0.0065 16.5 0.0 0.017 15.2 0.0 1.8 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain MeaB PF03308.16 AIN97973.1 - 0.19 10.6 0.0 0.33 9.9 0.0 1.2 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB CobA_CobO_BtuR PF02572.15 AIN97973.1 - 0.21 11.8 0.4 0.67 10.2 0.2 1.8 2 0 0 2 2 2 0 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP MORN PF02493.20 AIN97975.1 - 6.1e-18 63.6 40.2 0.00059 19.6 1.2 6.8 7 0 0 7 7 7 6 MORN repeat Phage_TTP_12 PF16461.5 AIN97978.1 - 0.11 12.3 0.0 0.25 11.0 0.0 1.6 1 0 0 1 1 1 0 Lambda phage tail tube protein, TTP Kinesin PF00225.23 AIN97979.1 - 9.6e-79 264.7 8.3 3.2e-74 249.8 0.0 3.2 3 1 0 3 3 3 2 Kinesin motor domain Microtub_bd PF16796.5 AIN97979.1 - 4.3e-10 39.7 0.5 0.00038 20.4 0.0 3.1 3 0 0 3 3 3 2 Microtubule binding APG6_N PF17675.1 AIN97979.1 - 0.016 15.8 5.1 0.016 15.8 5.1 4.3 4 1 0 4 4 4 0 Apg6 coiled-coil region CLZ PF16526.5 AIN97979.1 - 0.04 14.3 0.4 0.04 14.3 0.4 3.3 3 0 0 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels DUF2203 PF09969.9 AIN97979.1 - 0.14 12.9 0.2 0.14 12.9 0.2 5.2 4 2 1 6 6 6 0 Uncharacterized conserved protein (DUF2203) Fib_alpha PF08702.10 AIN97979.1 - 0.29 11.3 12.6 4.6 7.4 3.3 3.8 3 1 0 3 3 3 0 Fibrinogen alpha/beta chain family Gon7 PF08738.10 AIN97979.1 - 0.37 10.9 8.6 0.19 11.8 0.1 4.1 4 0 0 4 4 4 0 Gon7 family DUF4407 PF14362.6 AIN97979.1 - 7.1 5.9 22.1 1.3 8.3 0.9 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF4407) Cep57_CLD_2 PF14197.6 AIN97979.1 - 7.2 6.8 23.7 2.7 8.1 1.8 5.0 4 0 0 4 4 4 0 Centrosome localisation domain of PPC89 TPR_14 PF13428.6 AIN97980.1 - 3.8e-07 30.4 7.7 1.2 10.1 0.2 5.9 3 1 3 6 6 6 3 Tetratricopeptide repeat Suf PF05843.14 AIN97980.1 - 0.0018 18.3 4.3 0.18 11.8 0.1 3.4 3 1 0 3 3 3 2 Suppressor of forked protein (Suf) TPR_2 PF07719.17 AIN97980.1 - 0.026 14.6 4.3 26 5.2 0.1 5.0 5 0 0 5 5 5 0 Tetratricopeptide repeat NRDE-2 PF08424.10 AIN97980.1 - 0.029 13.5 0.2 0.63 9.1 0.1 2.2 2 0 0 2 2 2 0 NRDE-2, necessary for RNA interference TPR_1 PF00515.28 AIN97980.1 - 0.047 13.5 0.1 2.5 8.1 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.6 AIN97980.1 - 0.23 11.8 0.4 49 4.5 0.0 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat HEAT PF02985.22 AIN97981.1 - 7.8e-29 97.3 42.9 0.00047 20.2 0.2 13.8 15 0 0 15 15 15 9 HEAT repeat HEAT_2 PF13646.6 AIN97981.1 - 1e-27 96.3 23.7 9.9e-09 35.5 0.4 8.1 3 3 5 8 8 8 8 HEAT repeats Cnd1 PF12717.7 AIN97981.1 - 3.9e-09 36.8 7.2 0.0067 16.5 0.1 5.1 1 1 1 5 5 5 2 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.7 AIN97981.1 - 2.3e-08 34.5 0.1 0.0013 19.2 0.0 5.7 2 1 2 6 6 6 1 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.6 AIN97981.1 - 6.9e-08 32.8 29.2 9.6e-05 22.8 0.2 8.3 8 4 3 11 11 11 2 HEAT-like repeat Adaptin_N PF01602.20 AIN97981.1 - 1.9e-05 23.5 4.7 0.0016 17.1 2.4 2.9 2 1 1 3 3 3 2 Adaptin N terminal region CLASP_N PF12348.8 AIN97981.1 - 0.0011 18.6 1.3 1.5 8.3 0.1 4.1 1 1 3 4 4 4 2 CLASP N terminal Arm PF00514.23 AIN97981.1 - 0.7 10.0 5.4 44 4.3 0.0 4.9 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat HEAT_PBS PF03130.16 AIN97981.1 - 2.6 9.0 5.5 6.5 7.7 0.0 4.6 4 1 0 4 4 4 0 PBS lyase HEAT-like repeat Tfb2 PF03849.14 AIN97982.1 - 0.0083 15.1 0.6 0.011 14.7 0.6 1.1 1 0 0 1 1 1 1 Transcription factor Tfb2 Slp PF03843.13 AIN97982.1 - 0.073 12.4 0.9 6.3 6.1 0.0 2.2 1 1 1 2 2 2 0 Outer membrane lipoprotein Slp family Acyl-CoA_dh_C PF12806.7 AIN97982.1 - 0.12 12.5 0.0 0.2 11.8 0.0 1.3 1 0 0 1 1 1 0 Acetyl-CoA dehydrogenase C-terminal like DUF775 PF05603.12 AIN97983.1 - 2.9e-21 75.9 0.0 4.3e-21 75.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF775) Cupin_3 PF05899.12 AIN97983.1 - 0.14 11.9 0.0 0.27 10.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF861) Pkinase PF00069.25 AIN97987.1 - 3.7e-55 187.1 0.0 6.1e-55 186.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 AIN97987.1 - 2.1e-35 122.2 0.0 3.4e-35 121.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase cNMP_binding PF00027.29 AIN97987.1 - 3.4e-16 59.1 0.5 1.8e-07 31.1 0.1 4.3 4 0 0 4 4 4 3 Cyclic nucleotide-binding domain PAS PF00989.25 AIN97987.1 - 6.6e-06 26.1 0.0 2.1e-05 24.5 0.0 1.8 1 0 0 1 1 1 1 PAS fold PAS_9 PF13426.7 AIN97987.1 - 6.8e-05 23.1 0.0 0.00017 21.8 0.0 1.7 1 0 0 1 1 1 1 PAS domain Kinase-like PF14531.6 AIN97987.1 - 0.00069 19.0 0.0 0.0055 16.1 0.0 2.0 2 0 0 2 2 2 1 Kinase-like PAS_4 PF08448.10 AIN97987.1 - 0.0064 16.7 0.0 0.028 14.7 0.0 2.1 2 0 0 2 2 2 1 PAS fold PAS_3 PF08447.12 AIN97987.1 - 0.016 15.5 0.0 0.038 14.3 0.0 1.6 1 0 0 1 1 1 0 PAS fold Tubulin_3 PF14881.6 AIN97988.1 - 7.2e-05 22.5 0.0 0.00015 21.5 0.0 1.5 1 0 0 1 1 1 1 Tubulin domain Misat_Tub_SegII PF10644.9 AIN97988.1 - 0.0065 16.8 0.0 0.015 15.6 0.0 1.6 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain TTL PF03133.15 AIN97989.1 - 2.3e-44 151.7 0.0 3.4e-42 144.6 0.0 2.2 1 1 0 1 1 1 1 Tubulin-tyrosine ligase family MHB PF16525.5 AIN97990.1 - 0.57 10.5 11.9 0.66 10.3 0.1 3.9 4 1 1 5 5 5 0 Haemophore, haem-binding Androgen_recep PF02166.16 AIN97990.1 - 8.3 5.1 12.7 13 4.5 8.4 2.3 2 0 0 2 2 2 0 Androgen receptor AAA PF00004.29 AIN97991.1 - 5.4e-49 166.0 0.0 1.8e-36 125.5 0.0 2.9 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 AIN97991.1 - 2e-09 37.1 0.0 4.2e-09 36.1 0.0 1.6 1 0 0 1 1 1 1 AAA+ lid domain AAA_22 PF13401.6 AIN97991.1 - 2.8e-08 34.1 0.9 0.062 13.6 0.0 4.5 2 2 2 4 4 4 1 AAA domain AAA_18 PF13238.6 AIN97991.1 - 1.3e-07 32.3 0.0 0.02 15.4 0.0 2.9 2 0 0 2 2 2 2 AAA domain AAA_5 PF07728.14 AIN97991.1 - 2.2e-07 31.0 0.0 0.0038 17.2 0.0 3.0 3 0 0 3 3 2 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 AIN97991.1 - 1e-06 29.2 0.1 0.059 13.8 0.0 3.1 2 1 0 2 2 2 2 AAA ATPase domain Mg_chelatase PF01078.21 AIN97991.1 - 9e-06 25.2 0.0 0.0033 16.8 0.1 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI TIP49 PF06068.13 AIN97991.1 - 1.1e-05 24.8 0.0 0.031 13.5 0.0 2.2 2 0 0 2 2 2 2 TIP49 P-loop domain RuvB_N PF05496.12 AIN97991.1 - 0.00017 21.4 0.0 0.077 12.7 0.0 2.8 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain RNA_helicase PF00910.22 AIN97991.1 - 0.0005 20.4 0.0 0.63 10.5 0.0 2.7 2 0 0 2 2 2 1 RNA helicase AAA_7 PF12775.7 AIN97991.1 - 0.00054 19.5 0.0 0.0069 15.9 0.0 2.3 2 0 0 2 2 2 1 P-loop containing dynein motor region IstB_IS21 PF01695.17 AIN97991.1 - 0.00056 19.7 0.0 0.078 12.7 0.0 2.6 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_30 PF13604.6 AIN97991.1 - 0.00077 19.2 0.0 0.8 9.4 0.0 2.9 3 0 0 3 3 2 1 AAA domain Sigma54_activat PF00158.26 AIN97991.1 - 0.0008 19.2 0.0 0.4 10.4 0.0 2.6 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_33 PF13671.6 AIN97991.1 - 0.0008 19.6 0.0 0.66 10.1 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_3 PF07726.11 AIN97991.1 - 0.00082 19.2 0.0 0.4 10.5 0.0 2.5 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.6 AIN97991.1 - 0.0009 19.7 0.2 1.3 9.5 0.0 3.4 3 0 0 3 3 3 1 AAA domain AAA_28 PF13521.6 AIN97991.1 - 0.001 19.3 0.0 2 8.7 0.0 2.6 2 0 0 2 2 2 2 AAA domain Sigma54_activ_2 PF14532.6 AIN97991.1 - 0.0012 19.0 0.0 1.2 9.2 0.0 2.6 2 0 0 2 2 2 1 Sigma-54 interaction domain NACHT PF05729.12 AIN97991.1 - 0.0012 18.8 0.1 1.1 9.2 0.1 3.7 3 1 0 3 3 3 1 NACHT domain AAA_2 PF07724.14 AIN97991.1 - 0.0037 17.4 0.0 0.018 15.2 0.0 2.2 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_19 PF13245.6 AIN97991.1 - 0.0058 17.0 1.0 1.2 9.5 0.1 3.2 4 0 0 4 4 3 1 AAA domain ABC_tran PF00005.27 AIN97991.1 - 0.0086 16.6 0.1 0.75 10.3 0.0 3.1 2 1 1 3 3 3 1 ABC transporter TsaE PF02367.17 AIN97991.1 - 0.0098 15.9 0.0 0.51 10.4 0.0 2.3 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE DUF2075 PF09848.9 AIN97991.1 - 0.011 15.0 0.8 4.7 6.3 0.0 2.9 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) Zeta_toxin PF06414.12 AIN97991.1 - 0.011 15.0 0.1 0.63 9.3 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin DUF1599 PF07659.11 AIN97991.1 - 0.017 15.5 0.1 0.044 14.3 0.1 1.7 1 0 0 1 1 1 0 Nucleotide modification associated domain 1 CDC48_N PF02359.18 AIN97991.1 - 0.023 14.9 0.0 0.089 13.0 0.0 2.0 1 1 0 1 1 1 0 Cell division protein 48 (CDC48), N-terminal domain AAA_24 PF13479.6 AIN97991.1 - 0.025 14.3 0.0 0.38 10.4 0.0 2.5 2 0 0 2 2 2 0 AAA domain Cytidylate_kin PF02224.18 AIN97991.1 - 0.027 14.2 0.0 1 9.0 0.0 2.4 2 0 0 2 2 2 0 Cytidylate kinase KTI12 PF08433.10 AIN97991.1 - 0.027 13.9 0.0 9.4 5.6 0.0 2.6 3 0 0 3 3 3 0 Chromatin associated protein KTI12 AAA_11 PF13086.6 AIN97991.1 - 0.034 13.9 0.0 1.7 8.4 0.0 2.4 2 0 0 2 2 2 0 AAA domain T2SSE PF00437.20 AIN97991.1 - 0.042 12.9 0.0 6.1 5.8 0.0 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein ATPase PF06745.13 AIN97991.1 - 0.045 13.1 0.1 3.4 6.9 0.1 2.5 2 0 0 2 2 2 0 KaiC ResIII PF04851.15 AIN97991.1 - 0.051 13.6 0.1 9.9 6.1 0.2 3.2 2 1 0 2 2 2 0 Type III restriction enzyme, res subunit PhoH PF02562.16 AIN97991.1 - 0.07 12.6 0.0 0.77 9.2 0.0 2.2 2 0 0 2 2 2 0 PhoH-like protein AAA_29 PF13555.6 AIN97991.1 - 0.073 12.8 0.5 7.6 6.4 0.0 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_25 PF13481.6 AIN97991.1 - 0.12 11.9 1.1 6 6.4 0.1 3.2 3 0 0 3 3 3 0 AAA domain CPT PF07931.12 AIN97991.1 - 0.14 12.0 0.0 1.5 8.7 0.0 2.2 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein NB-ARC PF00931.22 AIN97991.1 - 0.15 11.3 0.0 8.1 5.6 0.0 2.3 2 0 0 2 2 2 0 NB-ARC domain GP46 PF07409.12 AIN97992.1 - 0.13 12.0 0.0 0.25 11.1 0.0 1.4 1 0 0 1 1 1 0 Phage protein GP46 ACPS PF01648.20 AIN97993.1 - 4.6e-12 46.1 0.0 7.8e-12 45.3 0.0 1.4 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily SCO1-SenC PF02630.14 AIN97994.1 - 8.2e-29 100.2 0.0 1.2e-26 93.2 0.0 2.3 1 1 0 1 1 1 1 SCO1/SenC Thioredoxin_8 PF13905.6 AIN97994.1 - 0.067 13.5 0.0 0.15 12.4 0.0 1.5 1 0 0 1 1 1 0 Thioredoxin-like TruD PF01142.18 AIN97995.1 - 1.2e-10 40.8 0.0 1.8e-06 27.1 0.0 3.3 4 0 0 4 4 4 2 tRNA pseudouridine synthase D (TruD) DUF5407 PF17401.2 AIN97995.1 - 0.12 12.6 0.7 0.35 11.2 0.7 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5407) DEAD PF00270.29 AIN97997.1 - 1.1e-28 100.2 0.1 2e-15 57.0 0.0 2.5 2 1 0 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.31 AIN97997.1 - 3.9e-16 59.4 0.0 1.3e-15 57.7 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 AIN97997.1 - 1.4e-06 28.4 0.0 9.8e-06 25.7 0.0 2.1 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit TniB PF05621.11 AIN97997.1 - 0.053 12.9 0.0 0.11 11.9 0.0 1.4 1 0 0 1 1 1 0 Bacterial TniB protein AAA_22 PF13401.6 AIN97997.1 - 0.058 13.7 1.0 4.4 7.6 0.1 2.7 2 0 0 2 2 2 0 AAA domain Elf1 PF05129.13 AIN97998.1 - 1.5e-18 66.6 0.4 2.5e-18 65.9 0.4 1.3 1 0 0 1 1 1 1 Transcription elongation factor Elf1 like Lar_restr_allev PF14354.6 AIN97998.1 - 0.077 13.4 0.8 0.34 11.3 0.1 2.2 2 0 0 2 2 2 0 Restriction alleviation protein Lar Elf1 PF05129.13 AIN97999.1 - 1.1e-13 51.0 0.1 1.8e-13 50.3 0.1 1.4 1 0 0 1 1 1 1 Transcription elongation factor Elf1 like Ribonuclease_3 PF00636.26 AIN98000.1 - 1.8e-05 25.3 0.0 4.7e-05 24.0 0.0 1.7 1 0 0 1 1 1 1 Ribonuclease III domain zf-C2H2_11 PF16622.5 AIN98000.1 - 0.059 13.1 0.0 0.13 12.0 0.0 1.6 1 0 0 1 1 1 0 zinc-finger C2H2-type DUF755 PF05501.11 AIN98001.1 - 0.24 11.7 6.3 0.64 10.3 6.3 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF755) AATF-Che1 PF13339.6 AIN98002.1 - 1e-14 55.4 0.1 1.9e-13 51.3 0.0 3.0 3 1 1 4 4 4 1 Apoptosis antagonizing transcription factor TRAUB PF08164.12 AIN98002.1 - 0.00017 22.0 0.1 0.00017 22.0 0.1 2.9 4 0 0 4 4 4 1 Apoptosis-antagonizing transcription factor, C-terminal EPL1 PF10513.9 AIN98002.1 - 0.0016 18.8 0.1 0.084 13.3 0.0 2.6 2 0 0 2 2 2 1 Enhancer of polycomb-like APG6_N PF17675.1 AIN98002.1 - 0.27 11.7 3.3 1.3 9.5 0.0 3.0 2 1 0 2 2 2 0 Apg6 coiled-coil region BUD22 PF09073.10 AIN98003.1 - 8 5.7 20.5 13 5.0 20.5 1.3 1 0 0 1 1 1 0 BUD22 PBP1_TM PF14812.6 AIN98004.1 - 3.8 8.0 6.6 0.68 10.3 2.6 1.8 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF4379 PF14311.6 AIN98005.1 - 3.4e-16 59.3 6.8 4.8e-10 39.6 3.4 2.7 2 0 0 2 2 2 2 Probable Zinc-ribbon domain HypA PF01155.19 AIN98005.1 - 0.027 14.5 0.9 0.081 13.0 0.9 1.8 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Zn-ribbon_8 PF09723.10 AIN98005.1 - 0.058 13.5 2.9 0.16 12.2 2.9 1.7 1 0 0 1 1 1 0 Zinc ribbon domain zinc_ribbon_4 PF13717.6 AIN98005.1 - 5.6 7.0 6.4 14 5.7 5.5 2.1 2 0 0 2 2 2 0 zinc-ribbon domain Pkinase PF00069.25 AIN98006.1 - 2.4e-49 168.1 0.1 2.1e-30 106.0 0.0 3.2 3 0 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.17 AIN98006.1 - 3.5e-31 108.4 0.0 6.2e-31 107.6 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 AIN98006.1 - 1.8e-05 23.7 1.0 0.00022 20.1 0.0 2.5 2 0 0 2 2 2 1 Fungal protein kinase Kinase-like PF14531.6 AIN98006.1 - 0.042 13.2 0.0 0.095 12.0 0.0 1.5 1 0 0 1 1 1 0 Kinase-like Kdo PF06293.14 AIN98006.1 - 0.091 12.1 0.0 0.18 11.1 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family PAS_8 PF13188.7 AIN98006.1 - 0.14 12.2 0.0 0.4 10.7 0.0 1.7 1 0 0 1 1 1 0 PAS domain ARD PF03079.14 AIN98007.1 - 6e-36 124.0 0.0 9.1e-36 123.4 0.0 1.3 1 0 0 1 1 1 1 ARD/ARD' family DUF953 PF06110.11 AIN98007.1 - 2.6e-13 49.6 0.0 4.5e-13 48.8 0.0 1.3 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF953) Cupin_2 PF07883.11 AIN98007.1 - 3.8e-08 32.9 0.0 6.4e-08 32.2 0.0 1.4 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.19 AIN98007.1 - 3.9e-07 30.1 0.1 1.1e-06 28.6 0.0 1.9 2 0 0 2 2 2 1 AraC-like ligand binding domain Cupin_1 PF00190.22 AIN98007.1 - 0.052 13.1 0.0 0.086 12.4 0.0 1.3 1 0 0 1 1 1 0 Cupin Glutaredoxin PF00462.24 AIN98010.1 - 3.6e-11 43.1 0.0 5e-11 42.7 0.0 1.2 1 0 0 1 1 1 1 Glutaredoxin SH3BGR PF04908.15 AIN98010.1 - 0.059 13.5 0.0 0.073 13.2 0.0 1.2 1 0 0 1 1 1 0 SH3-binding, glutamic acid-rich protein Thioredoxin_3 PF13192.6 AIN98010.1 - 0.16 12.0 0.0 0.22 11.6 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin domain Spem1 PF15670.5 AIN98016.1 - 0.0058 16.3 0.4 0.0058 16.3 0.4 2.6 2 1 0 2 2 2 1 Spermatid maturation protein 1 Zn_ribbon_17 PF17120.5 AIN98017.1 - 0.00028 20.4 5.1 0.0011 18.5 5.1 2.0 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-RING_2 PF13639.6 AIN98017.1 - 0.00038 20.7 3.3 0.0011 19.3 3.3 1.9 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 AIN98017.1 - 0.0062 16.8 8.3 0.016 15.5 8.3 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 AIN98017.1 - 0.0069 16.2 2.3 0.022 14.6 2.3 2.0 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 AIN98017.1 - 3.4 7.7 9.5 0.59 10.1 4.9 2.2 2 1 0 2 2 2 0 zinc-RING finger domain AAA PF00004.29 AIN98018.1 - 0.011 16.1 0.0 0.025 15.0 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) T2SSE PF00437.20 AIN98018.1 - 0.02 13.9 0.1 0.041 12.9 0.1 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein ATPase_2 PF01637.18 AIN98018.1 - 0.25 11.2 0.0 0.48 10.3 0.0 1.3 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea MORN PF02493.20 AIN98019.1 - 8.1e-08 31.7 11.4 0.0074 16.1 0.5 3.9 3 0 0 3 3 3 3 MORN repeat PI3_PI4_kinase PF00454.27 AIN98021.1 - 6.4e-47 160.5 0.0 1.4e-46 159.4 0.0 1.5 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FAT PF02259.23 AIN98021.1 - 4.8e-31 108.2 3.0 9.5e-31 107.3 3.0 1.5 1 0 0 1 1 1 1 FAT domain FATC PF02260.20 AIN98021.1 - 2.2e-09 37.0 0.0 5.4e-09 35.7 0.0 1.7 1 0 0 1 1 1 1 FATC domain TFCD_C PF12612.8 AIN98021.1 - 6.1e-05 22.9 0.3 0.00043 20.2 0.2 2.7 2 0 0 2 2 2 1 Tubulin folding cofactor D C terminal HEAT PF02985.22 AIN98021.1 - 0.00039 20.4 1.6 42 4.8 0.0 7.2 8 0 0 8 8 8 0 HEAT repeat Ku_PK_bind PF08785.11 AIN98021.1 - 0.061 13.5 0.6 4.5 7.4 0.0 3.6 4 0 0 4 4 4 0 Ku C terminal domain like TIP120 PF08623.10 AIN98021.1 - 0.16 11.7 0.6 29 4.4 0.1 3.0 2 1 0 2 2 2 0 TATA-binding protein interacting (TIP20) DnaJ PF00226.31 AIN98022.1 - 5.1e-18 65.0 2.5 6.2e-18 64.7 0.4 2.3 2 0 0 2 2 2 1 DnaJ domain Myb_DNA-binding PF00249.31 AIN98022.1 - 9.4e-05 22.5 12.8 0.0007 19.7 0.3 4.4 4 0 0 4 4 4 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 AIN98022.1 - 0.051 13.8 0.9 0.051 13.8 0.9 4.1 4 0 0 4 4 4 0 Myb-like DNA-binding domain YIF1 PF03878.15 AIN98023.1 - 2.9e-42 144.9 1.0 4.2e-42 144.3 1.0 1.2 1 0 0 1 1 1 1 YIF1 PRP38 PF03371.15 AIN98024.1 - 3.9e-12 46.4 0.0 6e-12 45.8 0.0 1.2 1 0 0 1 1 1 1 PRP38 family DUF5056 PF16479.5 AIN98025.1 - 0.35 11.1 1.3 1.8 8.8 0.2 2.5 2 1 1 3 3 3 0 Domain of unknown function (DUF5056) YjcB PF15940.5 AIN98025.1 - 0.42 10.8 5.7 0.9 9.8 4.3 2.3 2 1 0 2 2 2 0 Family of unknown function Peptidase_C2 PF00648.21 AIN98026.1 - 4.1e-61 206.6 0.0 5.8e-61 206.1 0.0 1.2 1 0 0 1 1 1 1 Calpain family cysteine protease DUF1935 PF09149.10 AIN98026.1 - 6.6e-34 116.4 0.1 1.2e-33 115.5 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1935) Calpain_III PF01067.22 AIN98026.1 - 0.0032 17.7 0.0 0.022 15.0 0.0 2.2 2 0 0 2 2 2 1 Calpain large subunit, domain III Peptidase_C2 PF00648.21 AIN98027.1 - 3.7e-61 206.7 0.0 5.3e-61 206.2 0.0 1.2 1 0 0 1 1 1 1 Calpain family cysteine protease DUF1935 PF09149.10 AIN98027.1 - 6.2e-34 116.5 0.1 1.1e-33 115.6 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1935) Calpain_III PF01067.22 AIN98027.1 - 0.0029 17.9 0.0 0.02 15.1 0.0 2.2 2 0 0 2 2 2 1 Calpain large subunit, domain III Peptidase_C2 PF00648.21 AIN98028.1 - 2.9e-55 187.4 0.0 6.1e-55 186.3 0.0 1.5 2 0 0 2 2 2 1 Calpain family cysteine protease DUF1935 PF09149.10 AIN98028.1 - 1e-32 112.5 0.2 2.1e-32 111.6 0.2 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1935) Tom6 PF17112.5 AIN98028.1 - 0.1 12.1 0.0 0.29 10.7 0.0 1.8 1 0 0 1 1 1 0 Mitochondrial import receptor subunit Tom6, fungal Peptidase_C2 PF00648.21 AIN98029.1 - 4.8e-46 157.1 0.0 7.2e-46 156.6 0.0 1.2 1 0 0 1 1 1 1 Calpain family cysteine protease DUF1935 PF09149.10 AIN98029.1 - 3.9e-25 88.2 0.0 8e-25 87.2 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1935) TetR_C_28 PF17937.1 AIN98029.1 - 0.087 13.3 0.2 0.19 12.2 0.2 1.5 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain TYW3 PF02676.14 AIN98029.1 - 0.16 11.3 0.0 0.29 10.5 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase TYW3 DUF1935 PF09149.10 AIN98030.1 - 0.0003 21.1 0.0 0.0006 20.2 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1935) Saf-Nte_pilin PF09460.10 AIN98030.1 - 0.15 12.0 0.0 0.39 10.7 0.0 1.7 1 0 0 1 1 1 0 Saf-pilin pilus formation protein Peptidase_C2 PF00648.21 AIN98031.1 - 7.9e-29 100.6 0.0 1.2e-28 100.0 0.0 1.3 1 0 0 1 1 1 1 Calpain family cysteine protease DUF1935 PF09149.10 AIN98032.1 - 7e-27 93.8 0.0 8.2e-27 93.6 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1935) DUF1935 PF09149.10 AIN98033.1 - 2.7e-27 95.2 0.0 3.5e-27 94.8 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1935) Raptor_N PF14538.6 AIN98034.1 - 2.5e-11 43.7 0.0 5.9e-11 42.5 0.0 1.6 1 0 0 1 1 1 1 Raptor N-terminal CASPase like domain WD40 PF00400.32 AIN98034.1 - 0.2 12.6 1.3 2.1 9.4 0.0 3.0 3 0 0 3 3 3 0 WD domain, G-beta repeat DUF1935 PF09149.10 AIN98035.1 - 2.8e-30 104.7 0.0 4.8e-30 104.0 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1935) DUF1935 PF09149.10 AIN98036.1 - 8.1e-05 23.0 0.0 0.55 10.6 0.0 2.5 2 0 0 2 2 2 2 Domain of unknown function (DUF1935) DUF1935 PF09149.10 AIN98037.1 - 4e-07 30.4 0.0 7.2e-07 29.5 0.0 1.3 1 1 0 1 1 1 1 Domain of unknown function (DUF1935) DUF1935 PF09149.10 AIN98038.1 - 2.8e-30 104.8 0.0 3.7e-30 104.4 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1935) NAP PF00956.18 AIN98039.1 - 3e-12 46.3 1.5 3.9e-08 32.8 0.0 2.2 1 1 1 2 2 2 2 Nucleosome assembly protein (NAP) Mst1_SARAH PF11629.8 AIN98039.1 - 0.024 14.7 0.3 0.082 13.0 0.3 1.9 1 0 0 1 1 1 0 C terminal SARAH domain of Mst1 DUF1935 PF09149.10 AIN98040.1 - 1e-33 115.8 0.1 1.2e-33 115.6 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1935) DUF1935 PF09149.10 AIN98041.1 - 1.3e-38 131.5 0.2 1.5e-38 131.3 0.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1935) TraS PF10624.9 AIN98041.1 - 0.063 13.2 0.0 0.083 12.8 0.0 1.2 1 0 0 1 1 1 0 Plasmid conjugative transfer entry exclusion protein TraS Thioredoxin_8 PF13905.6 AIN98042.1 - 0.00047 20.4 0.0 0.0011 19.2 0.0 1.6 2 0 0 2 2 2 1 Thioredoxin-like Pkinase PF00069.25 AIN98043.1 - 4.6e-29 101.6 0.0 6.6e-29 101.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 AIN98043.1 - 1.1e-14 54.4 0.0 2.5e-14 53.2 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 AIN98043.1 - 0.0025 17.2 0.0 0.099 11.9 0.0 2.2 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 AIN98043.1 - 0.068 11.9 0.0 0.099 11.4 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase Kdo PF06293.14 AIN98043.1 - 0.15 11.4 0.1 0.25 10.7 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Adaptin_N PF01602.20 AIN98044.1 - 5.2e-63 213.4 6.2 7.6e-63 212.9 6.2 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Coatomer_b_Cpla PF14806.6 AIN98044.1 - 9.6e-47 158.1 0.0 2.2e-46 157.0 0.0 1.6 1 0 0 1 1 1 1 Coatomer beta subunit appendage platform Coatamer_beta_C PF07718.12 AIN98044.1 - 8.9e-42 142.3 0.0 2.1e-41 141.1 0.0 1.7 1 0 0 1 1 1 1 Coatomer beta C-terminal region HEAT PF02985.22 AIN98044.1 - 4.1e-06 26.6 2.0 1.1 9.7 0.0 5.6 6 0 0 6 6 6 2 HEAT repeat HEAT_2 PF13646.6 AIN98044.1 - 2.7e-05 24.5 10.0 0.42 11.0 0.0 5.3 5 2 0 5 5 5 3 HEAT repeats Cnd1 PF12717.7 AIN98044.1 - 8.9e-05 22.6 4.0 0.00049 20.2 0.1 3.0 3 0 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 DUF5471 PF17565.2 AIN98044.1 - 0.0017 18.6 0.1 0.0047 17.2 0.1 1.7 1 0 0 1 1 1 1 Family of unknown function (DUF5471) TPP1 PF10341.9 AIN98044.1 - 0.12 12.3 0.3 0.41 10.6 0.1 2.0 2 0 0 2 2 2 0 Shelterin complex subunit, TPP1/ACD RNase_PH PF01138.21 AIN98045.1 - 0.0077 16.7 0.2 0.019 15.5 0.0 1.8 2 0 0 2 2 2 1 3' exoribonuclease family, domain 1 PUF PF00806.19 AIN98046.1 - 2.5e-19 67.8 0.0 0.0042 16.7 0.0 4.5 4 0 0 4 4 4 4 Pumilio-family RNA binding repeat ANAPC4_WD40 PF12894.7 AIN98047.1 - 0.014 15.7 0.0 1.4 9.3 0.0 2.7 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain AraC_binding PF02311.19 AIN98047.1 - 3.8 7.4 5.7 4.6 7.2 0.1 2.5 2 0 0 2 2 2 0 AraC-like ligand binding domain Trimer_CC PF08954.11 AIN98048.1 - 0.00031 20.2 22.1 0.0036 16.8 1.3 4.5 4 0 0 4 4 4 2 Trimerisation motif Macoilin PF09726.9 AIN98048.1 - 0.026 13.1 13.0 0.06 11.9 4.0 2.1 1 1 1 2 2 2 0 Macoilin family Tropomyosin_1 PF12718.7 AIN98048.1 - 0.051 13.7 13.8 0.54 10.4 0.4 3.3 3 0 0 3 3 3 0 Tropomyosin like TPD52 PF04201.15 AIN98048.1 - 0.079 12.6 4.0 0.068 12.8 0.9 2.3 2 0 0 2 2 2 0 Tumour protein D52 family bZIP_1 PF00170.21 AIN98048.1 - 0.4 10.8 6.2 1.6 8.9 2.5 2.7 2 0 0 2 2 2 0 bZIP transcription factor Cep57_CLD_2 PF14197.6 AIN98048.1 - 2.1 8.5 15.5 10 6.3 1.6 3.4 3 0 0 3 3 3 0 Centrosome localisation domain of PPC89 DUF1664 PF07889.12 AIN98048.1 - 2.3 8.2 5.4 8.5 6.4 0.2 3.2 3 1 0 3 3 3 0 Protein of unknown function (DUF1664) PRKCSH-like PF12999.7 AIN98048.1 - 3.2 7.5 4.7 0.63 9.8 0.1 2.1 3 0 0 3 3 3 0 Glucosidase II beta subunit-like GAS PF13851.6 AIN98048.1 - 3.7 6.8 15.6 0.41 10.0 1.0 3.2 3 0 0 3 3 3 0 Growth-arrest specific micro-tubule binding TMF_DNA_bd PF12329.8 AIN98048.1 - 4.7 7.3 8.0 24 5.0 1.4 3.5 3 0 0 3 3 3 0 TATA element modulatory factor 1 DNA binding Arm PF00514.23 AIN98049.1 - 1.3e-31 107.6 20.6 1.6e-05 24.8 0.1 8.4 9 0 0 9 9 9 7 Armadillo/beta-catenin-like repeat HEAT PF02985.22 AIN98049.1 - 5.3e-17 60.4 9.8 0.029 14.6 0.1 7.9 8 0 0 8 8 7 4 HEAT repeat HEAT_2 PF13646.6 AIN98049.1 - 1e-14 54.7 16.0 6.9e-05 23.2 0.2 5.1 3 2 1 4 4 4 4 HEAT repeats HEAT_EZ PF13513.6 AIN98049.1 - 4.3e-14 52.7 19.2 0.019 15.5 0.8 6.5 5 1 2 7 7 7 5 HEAT-like repeat Cnd1 PF12717.7 AIN98049.1 - 1.5e-12 47.9 0.2 0.0026 17.8 0.0 3.8 2 1 1 4 4 4 3 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.20 AIN98049.1 - 1.2e-11 44.0 1.2 1.7e-08 33.5 2.2 3.0 2 1 0 2 2 2 2 Adaptin N terminal region DNA_alkylation PF08713.11 AIN98049.1 - 5.5e-08 32.8 0.1 0.11 12.2 0.0 4.2 2 1 2 4 4 4 3 DNA alkylation repair enzyme CLASP_N PF12348.8 AIN98049.1 - 0.0002 21.0 0.9 0.93 9.0 0.2 3.2 1 1 1 2 2 2 2 CLASP N terminal CHASE6_C PF17150.4 AIN98049.1 - 0.00025 21.6 2.7 26 5.5 0.0 5.5 5 1 0 5 5 5 0 C-terminal domain of two-partite extracellular sensor domain RICTOR_N PF14664.6 AIN98049.1 - 0.00046 19.3 0.6 0.022 13.8 0.3 2.9 1 1 1 2 2 2 1 Rapamycin-insensitive companion of mTOR, N-term V-ATPase_H_C PF11698.8 AIN98049.1 - 0.00055 20.0 0.5 0.2 11.8 0.2 3.9 3 2 1 4 4 4 2 V-ATPase subunit H Proteasom_PSMB PF10508.9 AIN98049.1 - 0.00097 17.8 3.3 0.16 10.4 0.7 2.9 1 1 2 3 3 3 1 Proteasome non-ATPase 26S subunit Mo25 PF08569.11 AIN98049.1 - 0.001 18.5 0.1 0.32 10.3 0.1 2.4 1 1 1 2 2 2 2 Mo25-like HEAT_PBS PF03130.16 AIN98049.1 - 0.0021 18.6 11.3 0.15 12.8 0.5 5.7 7 0 0 7 7 5 1 PBS lyase HEAT-like repeat Vac14_Fab1_bd PF12755.7 AIN98049.1 - 0.016 15.8 0.2 0.65 10.6 0.0 3.3 1 1 3 4 4 4 0 Vacuolar 14 Fab1-binding region HEAT_UF PF18817.1 AIN98049.1 - 0.022 15.0 0.0 2.7 8.3 0.0 3.7 3 0 0 3 3 3 0 Repeat of uncharacterized protein PH0542 DUF3361 PF11841.8 AIN98049.1 - 0.054 13.4 0.5 2.9 7.8 0.1 3.2 3 1 0 3 3 3 0 Domain of unknown function (DUF3361) DUF4244 PF14029.6 AIN98050.1 - 0.18 11.2 2.0 0.27 10.7 0.5 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF4244) SET PF00856.28 AIN98052.1 - 0.00034 21.0 0.0 0.0017 18.8 0.0 1.9 1 1 0 1 1 1 1 SET domain BAT PF15915.5 AIN98052.1 - 0.063 13.2 0.2 0.23 11.3 0.1 1.9 2 0 0 2 2 2 0 GAF and HTH_10 associated domain ubiquitin PF00240.23 AIN98054.1 - 0.00014 21.5 0.0 0.013 15.3 0.0 3.3 4 0 0 4 4 4 1 Ubiquitin family C2 PF00168.30 AIN98055.1 - 0.13 12.6 0.0 0.21 11.9 0.0 1.3 1 0 0 1 1 1 0 C2 domain Myotub-related PF06602.14 AIN98058.1 - 3.9e-92 308.9 0.0 9.7e-92 307.6 0.0 1.6 1 1 0 1 1 1 1 Myotubularin-like phosphatase domain Y_phosphatase3 PF13350.6 AIN98058.1 - 0.011 15.8 0.0 0.022 14.7 0.0 1.5 1 0 0 1 1 1 0 Tyrosine phosphatase family FYVE_2 PF02318.16 AIN98058.1 - 0.061 13.5 7.2 0.16 12.2 7.2 1.7 1 0 0 1 1 1 0 FYVE-type zinc finger FYVE PF01363.21 AIN98058.1 - 0.62 10.3 12.0 1.9 8.7 12.0 1.8 1 0 0 1 1 1 0 FYVE zinc finger C1_4 PF07975.12 AIN98058.1 - 0.77 10.0 11.1 3.1 8.1 11.1 2.1 1 0 0 1 1 1 0 TFIIH C1-like domain HEAT PF02985.22 AIN98059.1 - 0.027 14.7 0.5 1.8 9.1 0.1 3.3 2 0 0 2 2 2 0 HEAT repeat DUF1834 PF08873.11 AIN98059.1 - 0.028 14.2 0.0 0.057 13.2 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1834) DNA_alkylation PF08713.11 AIN98060.1 - 1 9.0 5.3 0.51 10.0 2.1 1.9 2 0 0 2 2 2 0 DNA alkylation repair enzyme DUF4456 PF14644.6 AIN98062.1 - 3.3e-13 49.8 0.2 3.3e-13 49.8 0.2 4.2 3 0 0 3 3 3 1 Domain of unknown function (DUF4456) DUF4455 PF14643.6 AIN98062.1 - 1.5e-05 23.8 2.8 1.5e-05 23.8 2.8 4.3 4 1 0 4 4 4 1 Domain of unknown function (DUF4455) EMP24_GP25L PF01105.24 AIN98062.1 - 0.24 11.3 2.1 27 4.6 1.7 3.4 3 0 0 3 3 3 0 emp24/gp25L/p24 family/GOLD DUF1400 PF07176.11 AIN98062.1 - 0.62 10.4 4.4 0.64 10.3 0.5 2.8 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF1400) AAA PF00004.29 AIN98063.1 - 6.8e-25 88.0 0.0 4.2e-24 85.5 0.0 2.3 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 AIN98063.1 - 9.5e-06 26.1 2.2 5.4e-05 23.6 0.3 3.1 2 2 1 3 3 3 1 AAA ATPase domain ABC_tran PF00005.27 AIN98063.1 - 0.00024 21.6 0.0 0.00082 19.9 0.0 1.9 2 0 0 2 2 2 1 ABC transporter AAA_22 PF13401.6 AIN98063.1 - 0.00065 20.0 0.0 0.01 16.1 0.0 2.7 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.6 AIN98063.1 - 0.012 16.2 0.0 0.03 14.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 AIN98063.1 - 0.042 13.8 3.8 1.4 8.8 0.1 3.5 2 2 0 2 2 2 0 NACHT domain AAA_23 PF13476.6 AIN98063.1 - 0.046 14.2 0.0 0.36 11.3 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 AIN98063.1 - 0.053 13.3 0.0 0.18 11.5 0.0 1.9 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_33 PF13671.6 AIN98063.1 - 0.058 13.6 0.4 0.24 11.5 0.0 2.3 3 0 0 3 3 3 0 AAA domain AAA_5 PF07728.14 AIN98063.1 - 0.061 13.3 0.2 0.44 10.5 0.0 2.5 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) KAP_NTPase PF07693.14 AIN98063.1 - 0.073 12.3 0.0 1.8 7.8 0.0 2.6 2 1 1 3 3 3 0 KAP family P-loop domain AAA_21 PF13304.6 AIN98063.1 - 0.25 11.1 0.0 0.42 10.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_25 PF13481.6 AIN98063.1 - 0.55 9.8 4.3 6.3 6.3 0.2 3.3 2 1 1 3 3 3 0 AAA domain RabGAP-TBC PF00566.18 AIN98064.1 - 1.2e-14 54.5 0.7 1.6e-14 54.1 0.1 1.5 2 0 0 2 2 2 1 Rab-GTPase-TBC domain SGS PF05002.15 AIN98065.1 - 9.8e-32 108.9 0.7 1.6e-31 108.2 0.7 1.4 1 0 0 1 1 1 1 SGS domain CS PF04969.16 AIN98065.1 - 0.00056 20.9 0.0 0.0012 19.9 0.0 1.5 1 0 0 1 1 1 1 CS domain BsuPI PF12690.7 AIN98065.1 - 0.015 15.3 0.1 0.038 14.0 0.1 1.6 1 0 0 1 1 1 0 Intracellular proteinase inhibitor Ribosomal_S17_N PF16205.5 AIN98066.1 - 4.8e-28 97.3 0.7 4.8e-28 97.3 0.7 1.6 2 0 0 2 2 2 1 Ribosomal_S17 N-terminal Ribosomal_S17 PF00366.20 AIN98066.1 - 1.3e-22 79.7 0.7 1.3e-22 79.7 0.7 2.0 2 0 0 2 2 2 1 Ribosomal protein S17 XPG_I_2 PF12813.7 AIN98066.1 - 0.079 12.4 0.1 0.26 10.7 0.0 1.7 2 0 0 2 2 2 0 XPG domain containing DnaB_2 PF07261.11 AIN98067.1 - 0.12 12.2 0.0 0.23 11.2 0.0 1.4 1 0 0 1 1 1 0 Replication initiation and membrane attachment DotA PF11388.8 AIN98067.1 - 0.44 10.8 1.4 38 4.6 0.4 2.9 3 0 0 3 3 3 0 Phagosome trafficking protein DotA KleE PF17394.2 AIN98067.1 - 0.93 9.7 4.2 0.69 10.1 1.3 2.2 2 0 0 2 2 2 0 Uncharacterized KleE stable inheritance protein Brix PF04427.18 AIN98068.1 - 7.4e-34 117.5 0.0 1.1e-33 117.0 0.0 1.3 1 0 0 1 1 1 1 Brix domain Peptidase_C50 PF03568.17 AIN98069.1 - 3.1e-38 131.9 0.1 1.8e-36 126.1 0.1 2.5 1 1 0 1 1 1 1 Peptidase family C50 CHAT PF12770.7 AIN98069.1 - 3e-08 33.4 0.4 0.00036 20.0 0.1 2.7 2 0 0 2 2 2 2 CHAT domain SNAP PF14938.6 AIN98070.1 - 3.4e-58 197.3 11.7 3.8e-58 197.1 11.7 1.0 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP TPR_12 PF13424.6 AIN98070.1 - 2.3e-07 31.0 7.0 1.8e-06 28.2 1.1 3.1 2 1 2 4 4 4 2 Tetratricopeptide repeat TPR_MalT PF17874.1 AIN98070.1 - 0.0037 16.7 2.6 0.0067 15.8 2.3 1.5 1 1 0 1 1 1 1 MalT-like TPR region TPR_8 PF13181.6 AIN98070.1 - 0.013 15.6 9.9 0.26 11.6 0.7 4.6 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_7 PF13176.6 AIN98070.1 - 0.015 15.3 1.5 2.5 8.3 0.0 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat Foie-gras_1 PF11817.8 AIN98070.1 - 0.032 13.8 0.5 0.075 12.6 0.5 1.7 1 0 0 1 1 1 0 Foie gras liver health family 1 TPR_1 PF00515.28 AIN98070.1 - 0.064 13.1 0.7 0.064 13.1 0.7 4.6 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_6 PF13174.6 AIN98070.1 - 0.091 13.4 17.9 0.88 10.3 0.1 5.7 4 3 1 6 6 6 0 Tetratricopeptide repeat TPR_16 PF13432.6 AIN98070.1 - 0.11 13.2 7.3 4.6 8.0 0.3 4.4 4 1 1 5 5 5 0 Tetratricopeptide repeat DUF1033 PF06279.11 AIN98070.1 - 0.15 12.3 0.1 0.15 12.3 0.1 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF1033) TPR_2 PF07719.17 AIN98070.1 - 0.28 11.4 12.7 2.3 8.5 0.4 5.5 4 2 0 5 5 5 0 Tetratricopeptide repeat tRNA_U5-meth_tr PF05958.11 AIN98072.1 - 4.5e-18 65.4 0.0 4.3e-17 62.1 0.0 2.1 1 1 0 1 1 1 1 tRNA (Uracil-5-)-methyltransferase Methyltransf_31 PF13847.6 AIN98072.1 - 2.9e-10 40.1 0.0 5.1e-10 39.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 AIN98072.1 - 3.3e-09 37.3 0.0 9.8e-09 35.8 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.15 AIN98072.1 - 4.9e-06 26.3 0.0 8.6e-06 25.5 0.0 1.3 1 0 0 1 1 1 1 Conserved hypothetical protein 95 PCMT PF01135.19 AIN98072.1 - 1.9e-05 24.6 0.0 3.6e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_11 PF08241.12 AIN98072.1 - 5.7e-05 23.7 0.0 0.00023 21.7 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.14 AIN98072.1 - 7.8e-05 22.3 0.0 0.00015 21.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Ubie_methyltran PF01209.18 AIN98072.1 - 8.2e-05 22.0 0.0 0.00018 20.9 0.0 1.5 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_15 PF09445.10 AIN98072.1 - 0.00045 19.8 0.0 0.00077 19.1 0.0 1.3 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltransf_4 PF02390.17 AIN98072.1 - 0.0095 15.4 0.0 0.019 14.4 0.0 1.5 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_32 PF13679.6 AIN98072.1 - 0.011 15.7 0.0 0.023 14.7 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain PrmA PF06325.13 AIN98072.1 - 0.015 14.8 0.1 0.027 13.9 0.1 1.4 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) TPMT PF05724.11 AIN98072.1 - 0.018 14.7 0.0 0.15 11.7 0.0 2.0 2 0 0 2 2 2 0 Thiopurine S-methyltransferase (TPMT) DOT1 PF08123.13 AIN98072.1 - 0.021 14.4 0.0 0.043 13.3 0.0 1.4 1 0 0 1 1 1 0 Histone methylation protein DOT1 Methyltransf_18 PF12847.7 AIN98072.1 - 0.058 13.3 0.0 0.13 12.2 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain RNA_ligase PF09414.10 AIN98074.1 - 2.8e-22 79.8 0.0 4e-22 79.2 0.0 1.3 1 0 0 1 1 1 1 RNA ligase T4_Rnl2_C PF18043.1 AIN98074.1 - 1.4e-08 34.7 0.0 3.3e-08 33.5 0.0 1.6 1 0 0 1 1 1 1 T4 RNA ligase 2 C-terminal PDDEXK_7 PF04411.12 AIN98074.1 - 0.13 12.2 0.0 0.24 11.4 0.0 1.4 1 0 0 1 1 1 0 PD-(D/E)XK nuclease superfamily Osmo_MPGsynth PF09488.10 AIN98075.1 - 0.17 10.6 0.0 0.29 9.8 0.0 1.4 1 1 0 1 1 1 0 Mannosyl-3-phosphoglycerate synthase (osmo_MPGsynth) Peptidase_M20 PF01546.28 AIN98076.1 - 9.1e-31 107.2 0.2 1.3e-30 106.6 0.2 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 AIN98076.1 - 9.2e-10 38.4 0.0 2.2e-09 37.2 0.0 1.7 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M20 PF01546.28 AIN98077.1 - 2.5e-30 105.7 0.5 3.2e-30 105.4 0.5 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 AIN98077.1 - 1.1e-09 38.2 0.0 2.7e-09 36.9 0.0 1.6 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 AIN98077.1 - 0.048 13.3 0.0 0.067 12.9 0.0 1.2 1 0 0 1 1 1 0 Peptidase family M28 PPR_2 PF13041.6 AIN98078.1 - 1.4e-16 60.4 1.7 4.1e-05 23.7 0.0 5.5 5 0 0 5 5 5 3 PPR repeat family PPR_3 PF13812.6 AIN98078.1 - 2.3e-15 56.4 0.1 2.9e-05 24.0 0.0 5.1 4 1 0 5 5 5 3 Pentatricopeptide repeat domain PPR_long PF17177.4 AIN98078.1 - 2.2e-12 46.8 0.8 4.1e-05 23.0 0.0 3.5 2 1 1 3 3 3 3 Pentacotripeptide-repeat region of PRORP PPR_1 PF12854.7 AIN98078.1 - 3.8e-05 23.3 0.0 2.2 8.0 0.0 5.0 5 0 0 5 5 5 2 PPR repeat PPR PF01535.20 AIN98078.1 - 0.00012 22.1 5.9 0.46 10.9 0.2 5.5 6 0 0 6 6 6 2 PPR repeat Pkr1 PF08636.10 AIN98079.1 - 3.4e-06 27.1 8.2 4.2e-06 26.8 8.2 1.1 1 0 0 1 1 1 1 ER protein Pkr1 ANAPC4_WD40 PF12894.7 AIN98080.1 - 0.03 14.6 0.0 0.12 12.7 0.0 2.0 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 4 WD40 domain CHORD PF04968.12 AIN98082.1 - 5.4e-38 129.5 39.4 7.1e-21 74.7 12.6 2.6 3 0 0 3 3 3 2 CHORD Methyltransf_12 PF08242.12 AIN98083.1 - 2.1e-15 57.2 0.0 3.6e-14 53.3 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 AIN98083.1 - 2.8e-14 53.3 0.0 4.2e-14 52.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 AIN98083.1 - 1.6e-13 51.1 0.5 4.1e-10 40.2 0.0 3.5 3 1 0 3 3 3 1 Methyltransferase domain Methyltransf_25 PF13649.6 AIN98083.1 - 5.4e-13 49.5 0.1 4.9e-05 24.0 0.0 3.3 2 1 1 3 3 3 2 Methyltransferase domain Methyltransf_31 PF13847.6 AIN98083.1 - 2.4e-11 43.6 0.0 0.00012 21.9 0.0 2.3 2 0 0 2 2 2 2 Methyltransferase domain NodS PF05401.11 AIN98083.1 - 0.0034 17.0 0.1 0.008 15.8 0.0 1.6 2 0 0 2 2 2 1 Nodulation protein S (NodS) Ubie_methyltran PF01209.18 AIN98083.1 - 0.037 13.4 0.0 0.28 10.5 0.0 2.1 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_24 PF13578.6 AIN98083.1 - 0.16 13.0 0.0 0.53 11.3 0.0 2.0 1 1 0 1 1 1 0 Methyltransferase domain zf-rbx1 PF12678.7 AIN98084.1 - 1.4e-24 86.1 15.6 2.1e-24 85.6 15.6 1.3 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 AIN98084.1 - 2.6e-17 62.6 11.4 3.2e-17 62.4 11.4 1.1 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_2 PF13639.6 AIN98084.1 - 9.8e-06 25.8 17.8 0.00047 20.4 17.8 2.4 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 AIN98084.1 - 0.001 18.8 16.0 0.085 12.7 16.0 2.4 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 AIN98084.1 - 0.012 15.5 15.5 0.075 12.9 14.1 2.5 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 AIN98084.1 - 0.08 13.0 8.7 0.17 11.9 8.7 1.6 1 1 0 1 1 1 0 RING-type zinc-finger zf-C3HC4_3 PF13920.6 AIN98084.1 - 0.098 12.5 13.8 1.2 9.1 8.4 2.6 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 AIN98084.1 - 0.26 10.9 16.6 0.067 12.8 4.6 2.3 1 1 1 2 2 2 0 Zinc-ribbon, C4HC2 type zf-RING_11 PF17123.5 AIN98084.1 - 2.8 7.8 16.2 1.1e+02 2.7 16.2 2.5 1 1 0 1 1 1 0 RING-like zinc finger FANCL_C PF11793.8 AIN98084.1 - 3.7 7.8 12.8 27 5.0 12.9 2.2 1 1 0 1 1 1 0 FANCL C-terminal domain zf-RING_5 PF14634.6 AIN98084.1 - 5.8 7.0 14.7 74 3.4 14.8 2.4 1 1 0 1 1 1 0 zinc-RING finger domain bZIP_1 PF00170.21 AIN98086.1 - 0.037 14.1 0.4 2.7 8.1 0.0 2.8 2 0 0 2 2 2 0 bZIP transcription factor CLZ PF16526.5 AIN98086.1 - 0.093 13.1 1.1 9.7 6.6 0.0 3.1 3 0 0 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Tup_N PF08581.10 AIN98086.1 - 0.14 12.5 3.8 23 5.4 0.1 3.4 3 0 0 3 3 3 0 Tup N-terminal ALIX_LYPXL_bnd PF13949.6 AIN98087.1 - 1.2e-05 24.8 1.9 1.7e-05 24.3 1.9 1.2 1 0 0 1 1 1 1 ALIX V-shaped domain binding to HIV HEPN_Cthe2314 PF18730.1 AIN98087.1 - 0.0044 17.1 0.2 0.016 15.3 0.1 1.9 2 0 0 2 2 2 1 Cthe_2314-like HEPN FlaC_arch PF05377.11 AIN98087.1 - 0.0074 16.7 0.5 0.53 10.7 0.0 3.0 3 0 0 3 3 3 1 Flagella accessory protein C (FlaC) DUF5344 PF17279.2 AIN98087.1 - 0.06 13.9 0.4 0.43 11.2 0.0 2.5 3 1 0 3 3 3 0 Family of unknown function (DUF5344) Thg1 PF04446.12 AIN98087.1 - 0.083 12.9 0.9 0.23 11.5 0.9 2.1 1 1 0 1 1 1 0 tRNAHis guanylyltransferase OmpH PF03938.14 AIN98087.1 - 0.089 13.1 5.1 0.045 14.1 1.4 2.0 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) Nore1-SARAH PF16517.5 AIN98087.1 - 0.092 12.7 0.5 0.18 11.7 0.5 1.5 1 0 0 1 1 1 0 Novel Ras effector 1 C-terminal SARAH (Sav/Rassf/Hpo) domain DUF4686 PF15742.5 AIN98087.1 - 0.12 11.5 4.2 0.11 11.6 1.3 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4686) Seryl_tRNA_N PF02403.22 AIN98087.1 - 0.3 11.3 6.6 3.8 7.8 2.6 2.7 2 1 1 3 3 3 0 Seryl-tRNA synthetase N-terminal domain Ead_Ea22 PF13935.6 AIN98087.1 - 0.57 10.9 5.3 0.67 10.6 3.7 2.0 1 1 1 2 2 2 0 Ead/Ea22-like protein CREPT PF16566.5 AIN98087.1 - 0.72 10.0 4.9 1.3 9.2 0.0 2.8 2 1 0 2 2 2 0 Cell-cycle alteration and expression-elevated protein in tumour BRE1 PF08647.11 AIN98087.1 - 1.7 8.8 9.4 3.2 7.9 1.3 3.0 3 1 1 4 4 4 0 BRE1 E3 ubiquitin ligase CENP-H PF05837.12 AIN98087.1 - 2 8.8 7.7 1.1 9.7 0.1 2.9 2 1 1 3 3 3 0 Centromere protein H (CENP-H) SNARE PF05739.19 AIN98088.1 - 5.1e-07 29.6 1.7 5.1e-07 29.6 1.7 1.8 2 0 0 2 2 2 1 SNARE domain TrpBP PF02081.15 AIN98088.1 - 0.0076 16.1 0.0 0.015 15.1 0.0 1.4 1 0 0 1 1 1 1 Tryptophan RNA-binding attenuator protein Syntaxin-6_N PF09177.11 AIN98088.1 - 0.034 14.7 5.0 0.037 14.6 0.8 2.2 2 0 0 2 2 2 0 Syntaxin 6, N-terminal End3 PF12761.7 AIN98088.1 - 0.096 12.9 4.4 1 9.5 1.0 2.1 2 0 0 2 2 2 0 Actin cytoskeleton-regulatory complex protein END3 DUF745 PF05335.13 AIN98088.1 - 2.2 8.0 7.6 19 4.9 3.0 2.8 1 1 1 2 2 2 0 Protein of unknown function (DUF745) WD40 PF00400.32 AIN98090.1 - 3.2e-23 81.6 11.5 1.7e-08 34.9 0.0 6.6 7 0 0 7 7 7 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 AIN98090.1 - 2e-06 28.0 0.1 0.0035 17.6 0.0 3.7 3 1 1 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 AIN98090.1 - 8.1e-05 21.5 1.9 0.77 8.3 0.0 3.9 3 2 2 5 5 5 3 Nucleoporin Nup120/160 Nucleoporin_N PF08801.11 AIN98090.1 - 0.0041 15.9 0.1 7.2 5.2 0.0 4.1 3 2 1 4 4 4 2 Nup133 N terminal like baeRF_family2 PF18844.1 AIN98090.1 - 0.066 13.3 0.2 0.15 12.1 0.1 1.5 1 1 0 1 1 1 0 Bacterial archaeo-eukaryotic release factor family 2 DUF2480 PF10652.9 AIN98090.1 - 0.16 11.9 0.6 0.33 10.8 0.3 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2480) tRNA_bind_2 PF13725.6 AIN98091.1 - 0.18 11.5 0.0 0.29 10.8 0.0 1.2 1 0 0 1 1 1 0 Possible tRNA binding domain MFS_1 PF07690.16 AIN98092.1 - 2.2e-20 72.9 29.5 2.2e-20 72.9 29.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 AIN98092.1 - 1.1 8.1 31.2 0.12 11.2 11.1 2.3 2 0 0 2 2 2 0 Sugar (and other) transporter PgaD PF13994.6 AIN98093.1 - 0.015 15.3 0.4 0.029 14.4 0.4 1.5 1 0 0 1 1 1 0 PgaD-like protein Peptidase_C2 PF00648.21 AIN98096.1 - 4.6e-36 124.4 0.0 1.1e-35 123.2 0.0 1.6 1 0 0 1 1 1 1 Calpain family cysteine protease Calpain_III PF01067.22 AIN98096.1 - 3.6e-33 114.8 0.0 7.4e-09 36.0 0.0 7.0 5 2 0 5 5 5 5 Calpain large subunit, domain III Thioredoxin_2 PF13098.6 AIN98096.1 - 0.19 12.2 1.5 2.1 8.8 0.6 2.6 2 0 0 2 2 2 0 Thioredoxin-like domain Topoisom_bac PF01131.20 AIN98097.1 - 1.2e-75 255.1 0.0 2.2e-75 254.2 0.0 1.4 1 1 0 1 1 1 1 DNA topoisomerase Toprim PF01751.22 AIN98097.1 - 6.5e-15 55.2 0.0 1.5e-14 54.0 0.0 1.7 1 0 0 1 1 1 1 Toprim domain Toprim_4 PF13662.6 AIN98097.1 - 0.014 15.9 0.0 0.081 13.4 0.0 2.3 2 0 0 2 2 2 0 Toprim domain FliD_C PF07195.12 AIN98097.1 - 0.03 13.7 0.1 0.055 12.9 0.1 1.4 1 0 0 1 1 1 0 Flagellar hook-associated protein 2 C-terminus Sec3_C PF09763.9 AIN98097.1 - 0.043 12.2 0.1 0.15 10.4 0.0 1.7 2 0 0 2 2 2 0 Exocyst complex component Sec3 FleQ PF06490.11 AIN98097.1 - 0.1 13.0 0.0 0.24 11.8 0.0 1.5 1 0 0 1 1 1 0 Flagellar regulatory protein FleQ Pkinase PF00069.25 AIN98098.1 - 2.5e-54 184.4 0.0 4.3e-54 183.6 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 AIN98098.1 - 1.2e-30 106.7 0.0 1.9e-30 106.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Guanylate_cyc PF00211.20 AIN98098.1 - 0.00015 21.4 0.0 0.00035 20.2 0.0 1.5 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain Kinase-like PF14531.6 AIN98098.1 - 0.0062 15.9 0.0 0.037 13.3 0.0 2.2 2 1 0 2 2 2 1 Kinase-like Kdo PF06293.14 AIN98098.1 - 0.0066 15.8 0.0 0.014 14.7 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 AIN98098.1 - 0.0074 15.1 0.0 0.014 14.2 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase FTA2 PF13095.6 AIN98098.1 - 0.14 11.7 0.0 0.28 10.8 0.0 1.4 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 DUF5411 PF17424.2 AIN98098.1 - 0.78 9.7 2.8 1.6 8.7 2.8 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5411) RPN6_N PF18055.1 AIN98099.1 - 0.012 15.9 1.0 0.81 10.1 0.0 3.5 4 0 0 4 4 4 0 26S proteasome regulatory subunit RPN6 N-terminal domain Pox_A6 PF04924.12 AIN98099.1 - 0.19 10.6 0.0 0.37 9.7 0.0 1.4 1 0 0 1 1 1 0 Poxvirus A6 protein Pkinase PF00069.25 AIN98100.1 - 6.5e-37 127.3 0.0 1e-36 126.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 AIN98100.1 - 1.8e-13 50.4 0.0 5.4e-10 39.0 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 AIN98100.1 - 0.028 13.7 0.0 4.1 6.6 0.0 2.2 2 0 0 2 2 2 0 Kinase-like LRR_4 PF12799.7 AIN98101.1 - 6.9e-09 35.8 12.3 0.045 14.2 0.1 7.0 7 2 2 9 9 9 4 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 AIN98101.1 - 4.6e-06 26.2 18.7 2.6 8.3 0.0 10.3 13 0 0 13 13 13 3 Leucine Rich repeat LRR_8 PF13855.6 AIN98101.1 - 0.0065 16.2 16.4 3.2 7.6 0.2 7.6 6 2 2 8 8 8 3 Leucine rich repeat DUF2478 PF10649.9 AIN98101.1 - 0.052 13.2 0.0 0.14 11.7 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2478) LRR_1 PF00560.33 AIN98101.1 - 0.93 10.3 16.5 1.6e+02 3.5 0.0 8.6 12 1 0 12 12 12 0 Leucine Rich Repeat PUF PF00806.19 AIN98102.1 - 0.0058 16.3 3.3 7.8 6.4 0.0 5.7 6 1 1 7 7 7 1 Pumilio-family RNA binding repeat CHAT PF12770.7 AIN98103.1 - 5.1e-59 200.0 0.3 1.2e-58 198.9 0.3 1.6 1 0 0 1 1 1 1 CHAT domain LRR_6 PF13516.6 AIN98103.1 - 0.014 15.4 3.7 6.8 7.0 0.1 3.5 3 0 0 3 3 3 0 Leucine Rich repeat MVP_shoulder PF11978.8 AIN98105.1 - 2e-41 140.7 0.0 3.3e-41 140.0 0.0 1.4 1 0 0 1 1 1 1 Shoulder domain Vault_3 PF17795.1 AIN98105.1 - 1e-33 115.1 0.5 5.8e-31 106.3 0.1 3.8 4 0 0 4 4 4 1 Major Vault Protein Repeat domain Vault PF01505.18 AIN98105.1 - 4.6e-27 93.9 0.4 2.5e-11 43.5 0.1 4.3 4 0 0 4 4 4 3 Major Vault Protein repeat domain Vault_4 PF17796.1 AIN98105.1 - 2.1e-15 56.5 0.0 2.3e-13 50.0 0.0 3.4 3 0 0 3 3 3 1 Major Vault Protein repeat domain Vault_2 PF17794.1 AIN98105.1 - 8.4e-10 38.9 2.4 8.9e-05 22.8 0.1 4.2 3 1 0 3 3 3 2 Major Vault Protein repeat domain NopRA1 PF16201.5 AIN98106.1 - 0.024 14.2 0.1 0.046 13.3 0.1 1.4 1 0 0 1 1 1 0 Nucleolar pre-ribosomal-associated protein 1 ELYS PF13934.6 AIN98106.1 - 0.05 13.6 1.6 0.48 10.4 0.5 2.5 2 1 0 2 2 2 0 Nuclear pore complex assembly Gasdermin_C PF17708.1 AIN98106.1 - 0.061 13.4 1.1 0.3 11.2 0.1 2.5 3 0 0 3 3 3 0 Gasdermin PUB domain EF-hand_7 PF13499.6 AIN98107.1 - 3.8e-11 43.3 0.1 7.8e-06 26.2 0.1 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 AIN98107.1 - 1.4e-08 34.0 1.3 0.0077 16.1 0.0 2.9 3 0 0 3 3 3 2 EF-hand domain EF-hand_1 PF00036.32 AIN98107.1 - 2.9e-07 29.6 0.0 0.016 14.7 0.0 2.7 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 AIN98107.1 - 4.2e-07 29.7 0.1 0.0014 18.4 0.1 3.2 1 1 2 3 3 3 2 EF-hand domain pair EF-hand_9 PF14658.6 AIN98107.1 - 5.5e-06 26.6 0.4 0.00017 21.9 0.0 2.8 2 1 1 3 3 3 1 EF-hand domain SPARC_Ca_bdg PF10591.9 AIN98107.1 - 0.015 15.6 0.0 1.6 9.1 0.0 2.3 1 1 1 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region Dehydratase_SU PF02287.15 AIN98107.1 - 0.039 14.0 0.0 0.062 13.4 0.0 1.3 1 0 0 1 1 1 0 Dehydratase small subunit DUF384 PF04064.13 AIN98107.1 - 0.18 11.7 2.7 1.1 9.2 0.3 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF384) Actin PF00022.19 AIN98108.1 - 3.2e-35 121.5 0.0 3.5e-34 118.1 0.0 2.0 1 1 0 1 1 1 1 Actin Hexokinase_2 PF03727.16 AIN98109.1 - 2.4e-61 207.2 0.0 3.5e-61 206.7 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.21 AIN98109.1 - 1.3e-60 204.7 0.0 1.8e-60 204.2 0.0 1.2 1 0 0 1 1 1 1 Hexokinase PPR_2 PF13041.6 AIN98110.1 - 2.6e-12 46.7 2.3 1.3e-06 28.5 0.1 3.9 4 0 0 4 4 4 2 PPR repeat family PPR_3 PF13812.6 AIN98110.1 - 6.2e-11 42.2 0.1 1.1e-06 28.6 0.0 4.2 4 0 0 4 4 4 1 Pentatricopeptide repeat domain PPR_long PF17177.4 AIN98110.1 - 6.9e-06 25.6 0.2 0.0033 16.8 0.0 3.3 3 1 0 3 3 3 1 Pentacotripeptide-repeat region of PRORP PPR PF01535.20 AIN98110.1 - 0.0016 18.6 2.4 32 5.1 0.1 6.2 7 0 0 7 7 7 0 PPR repeat PPR_1 PF12854.7 AIN98110.1 - 0.0099 15.6 0.0 0.83 9.4 0.0 3.0 2 0 0 2 2 2 1 PPR repeat TPR_14 PF13428.6 AIN98110.1 - 0.049 14.5 0.1 8.1 7.6 0.0 4.1 3 0 0 3 3 3 0 Tetratricopeptide repeat ECSIT PF06239.11 AIN98110.1 - 0.082 12.0 0.0 0.26 10.4 0.0 1.8 2 0 0 2 2 2 0 Evolutionarily conserved signalling intermediate in Toll pathway GMP_synt_C PF00958.22 AIN98110.1 - 0.11 12.5 0.1 4.7 7.3 0.0 2.6 2 0 0 2 2 2 0 GMP synthase C terminal domain Pkinase PF00069.25 AIN98111.1 - 9.3e-48 162.9 0.0 1.3e-46 159.2 0.0 2.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 AIN98111.1 - 1.1e-29 103.6 0.5 3.3e-21 75.8 0.1 3.0 3 0 0 3 3 3 2 Protein tyrosine kinase RIO1 PF01163.22 AIN98111.1 - 0.002 17.8 0.3 0.0041 16.7 0.3 1.5 1 0 0 1 1 1 1 RIO1 family APH PF01636.23 AIN98111.1 - 0.0094 15.9 6.9 2.1 8.2 0.0 3.7 2 2 1 3 3 3 2 Phosphotransferase enzyme family zf-U1 PF06220.12 AIN98116.1 - 0.00026 20.7 4.8 0.00026 20.7 4.8 2.0 2 0 0 2 2 2 1 U1 zinc finger zf-C2H2_jaz PF12171.8 AIN98116.1 - 0.0044 17.3 0.4 0.012 15.8 0.4 1.8 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding AKAP95 PF04988.12 AIN98116.1 - 0.011 15.9 0.5 0.016 15.4 0.5 1.2 1 0 0 1 1 1 0 A-kinase anchoring protein 95 (AKAP95) cIII PF08134.11 AIN98116.1 - 0.012 15.4 0.1 0.024 14.4 0.1 1.5 1 0 0 1 1 1 0 cIII protein family Vps51 PF08700.11 AIN98117.1 - 1.3e-24 86.0 1.7 4.1e-24 84.5 1.7 1.9 1 0 0 1 1 1 1 Vps51/Vps67 Sec5 PF15469.6 AIN98117.1 - 6.4e-08 32.6 0.2 1.3e-07 31.7 0.2 1.5 1 0 0 1 1 1 1 Exocyst complex component Sec5 Dor1 PF04124.12 AIN98117.1 - 4.7e-07 28.8 3.2 8.2e-07 28.0 3.2 1.3 1 0 0 1 1 1 1 Dor1-like family Vps53_N PF04100.12 AIN98117.1 - 6.9e-06 25.3 2.0 1.3e-05 24.4 2.0 1.4 1 0 0 1 1 1 1 Vps53-like, N-terminal COG2 PF06148.11 AIN98117.1 - 3.2e-05 24.0 1.2 3.2e-05 24.0 1.2 2.3 3 0 0 3 3 3 1 COG (conserved oligomeric Golgi) complex component, COG2 Vps54_N PF10475.9 AIN98117.1 - 6e-05 22.5 3.5 0.00011 21.6 3.5 1.3 1 0 0 1 1 1 1 Vacuolar-sorting protein 54, of GARP complex CENP-F_leu_zip PF10473.9 AIN98117.1 - 0.018 15.1 3.5 0.045 13.8 3.5 1.7 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 SEO_N PF14576.6 AIN98117.1 - 0.034 13.3 0.5 0.066 12.4 0.5 1.4 1 0 0 1 1 1 0 Sieve element occlusion N-terminus COG5 PF10392.9 AIN98117.1 - 0.041 14.1 3.3 0.083 13.1 2.2 2.1 2 0 0 2 2 2 0 Golgi transport complex subunit 5 Occludin_ELL PF07303.13 AIN98117.1 - 0.082 13.6 1.2 0.15 12.8 0.1 2.0 2 0 0 2 2 1 0 Occludin homology domain BLOC1_2 PF10046.9 AIN98117.1 - 0.093 13.0 1.9 0.19 12.0 0.8 2.1 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 PhoU PF01895.19 AIN98117.1 - 0.31 11.5 1.3 2 9.0 1.3 2.5 1 1 0 1 1 1 0 PhoU domain DUF1664 PF07889.12 AIN98117.1 - 0.34 11.0 2.6 0.44 10.6 0.6 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) FlgN PF05130.12 AIN98117.1 - 5.3 7.6 7.7 0.75 10.3 1.8 2.6 2 1 0 2 2 2 0 FlgN protein NPV_P10 PF05531.12 AIN98117.1 - 9.4 6.8 7.9 0.87 10.1 0.9 3.0 4 0 0 4 4 3 0 Nucleopolyhedrovirus P10 protein Peptidase_M16 PF00675.20 AIN98118.1 - 5.6e-09 36.1 0.0 1.1e-08 35.2 0.0 1.5 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 AIN98118.1 - 0.0012 18.9 0.2 0.011 15.8 0.0 2.7 4 1 0 4 4 4 1 Peptidase M16 inactive domain DUF2922 PF11148.8 AIN98118.1 - 0.13 12.0 0.1 0.25 11.1 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2922) MCU PF04678.13 AIN98119.1 - 3.4e-20 72.9 1.4 4.1e-20 72.6 1.4 1.2 1 0 0 1 1 1 1 Mitochondrial calcium uniporter CCDC92 PF14916.6 AIN98120.1 - 0.037 13.8 0.1 0.085 12.6 0.1 1.6 1 0 0 1 1 1 0 Coiled-coil domain of unknown function ADIP PF11559.8 AIN98120.1 - 2.3 8.3 6.9 3.6 7.7 6.9 1.2 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding RPAP2_Rtr1 PF04181.13 AIN98121.1 - 2.1e-07 31.1 0.0 5.5e-05 23.4 0.0 2.6 2 1 0 2 2 2 2 Rtr1/RPAP2 family DUF5419 PF17441.2 AIN98121.1 - 0.045 13.9 0.0 0.096 12.8 0.0 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5419) DUF667 PF05018.13 AIN98122.1 - 3.9e-92 307.1 0.5 4.4e-92 306.9 0.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF667) UCH PF00443.29 AIN98124.1 - 1.5e-44 152.5 0.3 1.9e-44 152.1 0.3 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 AIN98124.1 - 1.3e-18 67.7 2.1 1.3e-18 67.7 2.1 2.1 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase Alpha-2-MRAP_N PF06400.11 AIN98124.1 - 0.0044 17.0 1.4 0.0095 15.9 1.4 1.5 1 0 0 1 1 1 1 Alpha-2-macroglobulin RAP, N-terminal domain Piwi PF02171.17 AIN98125.1 - 5e-09 35.8 0.0 7.4e-09 35.3 0.0 1.2 1 0 0 1 1 1 1 Piwi domain Pyr_redox_2 PF07992.14 AIN98126.1 - 4.2e-10 39.4 0.4 1.8e-05 24.1 0.1 3.2 2 1 1 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 AIN98126.1 - 1.3e-05 25.3 0.0 8e-05 22.8 0.0 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 AIN98126.1 - 0.00039 20.4 0.0 0.0011 19.0 0.0 1.8 1 0 0 1 1 1 1 FAD-NAD(P)-binding Pyr_redox PF00070.27 AIN98126.1 - 0.0017 18.9 0.0 0.19 12.3 0.0 2.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.20 AIN98126.1 - 0.061 13.4 0.2 67 3.5 0.0 3.4 3 0 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase Thi4 PF01946.17 AIN98126.1 - 0.069 12.4 0.0 0.15 11.3 0.0 1.5 1 0 0 1 1 1 0 Thi4 family PI3K_p85B PF02192.16 AIN98127.1 - 0.087 12.6 0.1 0.64 9.8 0.0 2.3 2 0 0 2 2 2 0 PI3-kinase family, p85-binding domain TFIIA PF03153.13 AIN98127.1 - 0.13 12.3 12.5 0.16 11.9 12.5 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PIEZO PF15917.5 AIN98127.1 - 0.64 9.5 5.8 1 8.8 5.8 1.3 1 0 0 1 1 1 0 Piezo MRP-S31 PF15433.6 AIN98127.1 - 0.92 9.1 7.7 1.3 8.6 7.7 1.1 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S31 TMEM189_B_dmain PF10520.9 AIN98128.1 - 1.7e-64 217.1 1.5 2.2e-64 216.7 1.5 1.1 1 0 0 1 1 1 1 B domain of TMEM189, localisation domain IBV_3A PF03617.13 AIN98128.1 - 0.019 15.0 0.7 0.04 13.9 0.7 1.5 1 0 0 1 1 1 0 IBV 3A protein FA_hydroxylase PF04116.13 AIN98128.1 - 0.029 14.7 4.8 0.29 11.5 2.7 2.2 1 1 1 2 2 2 0 Fatty acid hydroxylase superfamily Vps35 PF03635.17 AIN98130.1 - 1.7e-212 707.9 0.0 1.9e-212 707.7 0.0 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 35 Fib_alpha PF08702.10 AIN98131.1 - 0.055 13.7 5.6 0.099 12.8 1.7 2.6 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family FlxA PF14282.6 AIN98131.1 - 0.14 12.2 13.3 0.29 11.2 4.8 3.2 2 1 1 3 3 3 0 FlxA-like protein GAS PF13851.6 AIN98131.1 - 1.6 8.0 15.2 0.039 13.3 3.0 3.2 1 1 2 3 3 3 0 Growth-arrest specific micro-tubule binding Tropomyosin PF00261.20 AIN98131.1 - 1.9 7.8 25.1 1.1 8.5 10.6 3.8 3 1 0 3 3 3 0 Tropomyosin TPR_MLP1_2 PF07926.12 AIN98131.1 - 2 8.5 31.9 0.38 10.8 0.6 3.5 3 1 0 3 3 3 0 TPR/MLP1/MLP2-like protein BRE1 PF08647.11 AIN98131.1 - 2.5 8.2 0.0 2.5 8.2 0.0 3.5 1 1 1 2 2 2 0 BRE1 E3 ubiquitin ligase PRKG1_interact PF15898.5 AIN98131.1 - 2.5 9.0 10.1 2.2 9.2 2.8 3.7 2 1 2 4 4 4 0 cGMP-dependent protein kinase interacting domain Spc7 PF08317.11 AIN98131.1 - 3.2 6.5 21.8 1.1 8.1 9.3 2.6 2 1 1 3 3 3 0 Spc7 kinetochore protein Occludin_ELL PF07303.13 AIN98131.1 - 8.4 7.2 8.5 67 4.3 0.2 3.7 2 1 0 3 3 3 0 Occludin homology domain DUF848 PF05852.11 AIN98131.1 - 9.1 6.4 11.8 1.1 9.4 2.2 2.7 1 1 1 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) DnaJ_C PF01556.18 AIN98132.1 - 1e-30 106.7 0.0 1.6e-30 106.2 0.0 1.3 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 AIN98132.1 - 1.3e-26 92.5 1.9 2.2e-26 91.7 1.9 1.4 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 AIN98132.1 - 4.5e-13 49.4 14.5 8.4e-13 48.5 14.5 1.5 1 0 0 1 1 1 1 DnaJ central domain Anti-TRAP PF15777.5 AIN98132.1 - 0.041 13.8 7.7 0.43 10.6 1.1 2.6 2 0 0 2 2 2 0 Tryptophan RNA-binding attenuator protein inhibitory protein DZR PF12773.7 AIN98132.1 - 0.056 13.5 6.1 0.48 10.5 0.4 2.4 2 0 0 2 2 2 0 Double zinc ribbon PBP1_TM PF14812.6 AIN98132.1 - 0.12 12.8 2.6 0.3 11.5 2.6 1.6 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal CH PF00307.31 AIN98133.1 - 0.085 13.0 0.1 0.16 12.1 0.1 1.6 1 1 0 1 1 1 0 Calponin homology (CH) domain TPR_14 PF13428.6 AIN98136.1 - 2.2e-16 59.1 36.7 0.021 15.6 0.2 9.9 5 3 4 9 9 9 6 Tetratricopeptide repeat TPR_19 PF14559.6 AIN98136.1 - 1.9e-14 53.9 20.1 4.2e-05 24.0 0.0 7.0 6 2 2 8 8 8 5 Tetratricopeptide repeat TPR_2 PF07719.17 AIN98136.1 - 5.2e-12 44.9 22.0 0.011 15.8 0.1 8.3 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_1 PF00515.28 AIN98136.1 - 1e-11 44.1 10.1 0.022 14.6 0.1 6.5 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_12 PF13424.6 AIN98136.1 - 1.7e-07 31.4 24.3 0.15 12.4 0.2 6.3 4 2 1 5 5 5 5 Tetratricopeptide repeat ANAPC3 PF12895.7 AIN98136.1 - 6.7e-07 29.4 12.2 0.24 11.6 0.0 5.2 4 2 1 5 5 5 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.6 AIN98136.1 - 7.6e-07 29.7 37.3 0.00036 21.1 0.1 7.4 5 2 1 6 6 5 4 Tetratricopeptide repeat TPR_7 PF13176.6 AIN98136.1 - 1.4e-05 24.8 12.0 3.6 7.8 0.0 6.4 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_8 PF13181.6 AIN98136.1 - 6.2e-05 22.9 6.4 5.5 7.5 0.0 5.6 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_10 PF13374.6 AIN98136.1 - 9.9e-05 22.1 10.4 0.086 12.7 0.2 5.2 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_9 PF13371.6 AIN98136.1 - 0.0071 16.5 0.4 0.0071 16.5 0.4 6.1 5 1 1 6 6 6 1 Tetratricopeptide repeat HrpB1_HrpK PF09613.10 AIN98136.1 - 0.066 12.9 5.2 8.9 6.0 0.1 4.4 4 1 1 5 5 5 0 Bacterial type III secretion protein (HrpB1_HrpK) TPR_11 PF13414.6 AIN98136.1 - 0.07 12.8 7.4 25 4.7 0.0 5.3 5 0 0 5 5 5 0 TPR repeat TPR_17 PF13431.6 AIN98136.1 - 0.071 13.5 7.0 1.3e+02 3.3 0.0 5.9 5 0 0 5 5 5 0 Tetratricopeptide repeat SRP_TPR_like PF17004.5 AIN98136.1 - 0.11 12.5 0.0 13 5.9 0.0 2.9 3 0 0 3 3 3 0 Putative TPR-like repeat TPR_5 PF12688.7 AIN98136.1 - 1.3 9.2 12.7 0.93 9.8 3.0 4.6 4 1 1 5 5 5 0 Tetratrico peptide repeat La PF05383.17 AIN98137.1 - 9.5e-22 76.8 0.0 2.1e-21 75.7 0.0 1.6 1 0 0 1 1 1 1 La domain RRM_1 PF00076.22 AIN98137.1 - 1e-06 28.5 0.2 8.1e-05 22.4 0.1 3.1 2 1 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 AIN98137.1 - 0.00094 19.3 0.1 0.017 15.2 0.0 2.2 2 0 0 2 2 2 1 RNA recognition motif RRM_3 PF08777.11 AIN98137.1 - 0.0014 18.7 2.3 0.015 15.3 0.5 2.7 2 1 0 2 2 2 1 RNA binding motif PTS_2-RNA PF01885.16 AIN98137.1 - 0.016 15.2 0.0 0.032 14.3 0.0 1.4 1 0 0 1 1 1 0 RNA 2'-phosphotransferase, Tpt1 / KptA family AbiEi_2 PF09952.9 AIN98137.1 - 0.02 15.1 0.0 1.1 9.4 0.0 2.4 2 0 0 2 2 2 0 Transcriptional regulator, AbiEi antitoxin, Type IV TA system Biotin_lipoyl PF00364.22 AIN98138.1 - 9.6e-15 54.2 0.1 1.8e-14 53.3 0.1 1.5 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.17 AIN98138.1 - 0.03 14.7 0.7 0.096 13.1 0.1 2.2 2 1 0 2 2 2 0 e3 binding domain HlyD_3 PF13437.6 AIN98138.1 - 0.037 14.7 0.1 0.087 13.5 0.1 1.6 1 0 0 1 1 1 0 HlyD family secretion protein Acetyltransf_16 PF05301.11 AIN98139.1 - 0.03 14.1 0.1 0.034 13.9 0.1 1.0 1 0 0 1 1 1 0 GNAT acetyltransferase, Mec-17 V-SNARE_C PF12352.8 AIN98139.1 - 0.032 14.5 0.9 0.063 13.6 0.9 1.6 1 1 0 1 1 1 0 Snare region anchored in the vesicle membrane C-terminus ISPD_C PF18706.1 AIN98139.1 - 0.043 13.5 0.1 0.051 13.2 0.1 1.1 1 0 0 1 1 1 0 D-ribitol-5-phosphate cytidylyltransferase C-terminal domain SNARE PF05739.19 AIN98139.1 - 0.095 12.7 0.8 0.29 11.2 0.4 1.9 2 0 0 2 2 2 0 SNARE domain Exc PF07825.11 AIN98140.1 - 0.014 15.3 1.1 0.4 10.7 0.1 2.8 2 0 0 2 2 2 0 Excisionase-like protein TPR_MLP1_2 PF07926.12 AIN98140.1 - 0.037 14.1 1.6 0.09 12.8 1.6 1.6 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein CsgE PF10627.9 AIN98140.1 - 0.13 12.4 0.0 0.47 10.7 0.0 1.9 1 0 0 1 1 1 0 Curli assembly protein CsgE Helicase_RecD PF05127.14 AIN98140.1 - 0.29 11.0 2.0 0.43 10.4 0.3 2.0 2 0 0 2 2 2 0 Helicase BssS PF13991.6 AIN98141.1 - 0.062 13.4 0.0 0.21 11.7 0.0 1.9 1 0 0 1 1 1 0 BssS protein family CTD_bind PF04818.13 AIN98141.1 - 0.12 13.3 0.0 0.74 10.7 0.0 2.2 2 0 0 2 2 2 0 RNA polymerase II-binding domain. DAGK_prokar PF01219.19 AIN98141.1 - 0.25 11.2 0.1 0.25 11.2 0.1 2.2 2 0 0 2 2 2 0 Prokaryotic diacylglycerol kinase Noelin-1 PF12308.8 AIN98142.1 - 0.038 14.0 0.1 0.11 12.5 0.1 1.7 1 0 0 1 1 1 0 Neurogenesis glycoprotein DEAD PF00270.29 AIN98144.1 - 1.7e-15 57.2 0.0 2.6e-11 43.6 0.0 2.4 2 0 0 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.31 AIN98144.1 - 6.7e-15 55.4 0.0 2.3e-14 53.7 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 AIN98144.1 - 0.00022 21.2 0.0 0.0008 19.4 0.0 1.7 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit PA PF02225.22 AIN98144.1 - 0.035 14.1 0.5 0.13 12.3 0.5 2.0 1 0 0 1 1 1 0 PA domain SecA_DEAD PF07517.14 AIN98144.1 - 0.085 12.1 0.2 0.18 11.0 0.0 1.6 2 0 0 2 2 2 0 SecA DEAD-like domain IMS PF00817.20 AIN98146.1 - 1.7e-12 47.5 0.0 1.8e-12 47.5 0.0 1.1 1 0 0 1 1 1 1 impB/mucB/samB family PanZ PF12568.8 AIN98146.1 - 0.15 11.8 0.0 0.15 11.8 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain, PanZ IMS PF00817.20 AIN98147.1 - 1.8e-47 161.1 0.1 2.8e-47 160.5 0.1 1.3 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.8 AIN98147.1 - 3.3e-06 27.8 0.0 7.8e-06 26.6 0.0 1.7 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.8 AIN98147.1 - 0.0081 16.4 0.0 0.017 15.4 0.0 1.6 1 0 0 1 1 1 1 IMS family HHH motif PGM_PMM_I PF02878.16 AIN98148.1 - 8e-31 106.6 0.0 1.5e-30 105.7 0.0 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_III PF02880.16 AIN98148.1 - 3.3e-26 91.7 0.0 1.1e-25 90.1 0.0 1.9 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.16 AIN98148.1 - 3.5e-10 40.4 0.2 2e-09 38.0 0.2 2.4 1 1 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.20 AIN98148.1 - 5.1e-08 33.0 0.0 1.3e-07 31.7 0.0 1.7 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain ParA PF10609.9 AIN98150.1 - 2.3e-85 286.0 0.0 2.9e-85 285.7 0.0 1.1 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 AIN98150.1 - 9.8e-13 48.3 0.0 2.3e-11 43.8 0.0 2.6 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.6 AIN98150.1 - 5.4e-07 29.7 0.5 1.2e-05 25.3 0.5 2.1 1 1 0 1 1 1 1 AAA domain MipZ PF09140.11 AIN98150.1 - 1.3e-06 27.9 0.0 2.1e-06 27.2 0.0 1.3 1 0 0 1 1 1 1 ATPase MipZ ArsA_ATPase PF02374.15 AIN98150.1 - 0.00064 19.0 0.3 0.002 17.4 0.1 1.8 2 0 0 2 2 2 1 Anion-transporting ATPase Fer4_NifH PF00142.18 AIN98150.1 - 0.01 15.3 0.0 0.098 12.1 0.2 2.1 2 0 0 2 2 2 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family MeaB PF03308.16 AIN98150.1 - 0.015 14.3 0.3 0.021 13.8 0.3 1.2 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_18 PF13238.6 AIN98150.1 - 0.027 15.0 0.0 0.043 14.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain ATP_bind_1 PF03029.17 AIN98150.1 - 0.1 12.3 0.1 0.21 11.4 0.1 1.5 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein CBP_BcsQ PF06564.12 AIN98150.1 - 0.12 11.8 0.1 0.47 9.9 0.1 1.8 2 0 0 2 2 2 0 Cellulose biosynthesis protein BcsQ AAA_16 PF13191.6 AIN98150.1 - 0.14 12.5 0.1 0.24 11.8 0.1 1.4 1 0 0 1 1 1 0 AAA ATPase domain AAA_26 PF13500.6 AIN98150.1 - 0.15 11.8 0.1 1.1 9.0 0.1 2.2 1 1 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 AIN98150.1 - 0.19 12.1 0.2 0.38 11.2 0.2 1.5 1 0 0 1 1 1 0 RNA helicase Lactamase_B PF00753.27 AIN98151.1 - 1.5e-17 64.2 0.3 5.2e-17 62.5 0.1 1.9 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily BLACT_WH PF17778.1 AIN98151.1 - 2.9e-11 43.2 0.0 6.3e-11 42.1 0.0 1.5 1 0 0 1 1 1 1 Beta-lactamase associated winged helix domain Lactamase_B_2 PF12706.7 AIN98151.1 - 6.6e-05 22.5 0.2 0.00018 21.1 0.1 1.8 2 0 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 AIN98151.1 - 0.0054 16.6 0.0 0.014 15.3 0.0 1.7 1 1 1 2 2 2 1 Beta-lactamase superfamily domain Hist_deacetyl PF00850.19 AIN98152.1 - 1.8e-66 224.7 0.0 2.4e-66 224.3 0.0 1.1 1 0 0 1 1 1 1 Histone deacetylase domain DSPc PF00782.20 AIN98154.1 - 7.9e-18 64.5 0.0 1.1e-17 64.0 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain ABC_tran PF00005.27 AIN98155.1 - 1.3e-36 126.1 0.0 3e-17 63.4 0.0 2.4 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 AIN98155.1 - 1e-10 41.9 3.7 0.0086 15.9 0.0 4.2 3 1 1 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 AIN98155.1 - 1.6e-10 40.8 2.1 0.00074 19.0 0.2 3.9 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain RLI PF04068.15 AIN98155.1 - 5.1e-09 35.8 5.5 1.4e-08 34.4 5.5 1.8 1 0 0 1 1 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI Fer4 PF00037.27 AIN98155.1 - 1.1e-07 31.3 2.2 1.1e-07 31.3 2.2 2.2 2 0 0 2 2 2 1 4Fe-4S binding domain AAA_15 PF13175.6 AIN98155.1 - 2.6e-06 27.4 0.0 0.039 13.7 0.0 3.3 3 0 0 3 3 3 2 AAA ATPase domain AAA_16 PF13191.6 AIN98155.1 - 7.2e-06 26.5 0.0 0.012 16.0 0.0 2.5 2 1 0 2 2 2 2 AAA ATPase domain AAA_23 PF13476.6 AIN98155.1 - 6.5e-05 23.5 0.5 0.061 13.8 0.1 2.5 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 AIN98155.1 - 8.6e-05 22.2 0.2 0.17 11.6 0.0 2.4 2 0 0 2 2 2 2 P-loop containing region of AAA domain Fer4_6 PF12837.7 AIN98155.1 - 9.9e-05 22.3 15.3 0.00011 22.1 2.3 2.6 2 0 0 2 2 2 1 4Fe-4S binding domain AAA_22 PF13401.6 AIN98155.1 - 0.00013 22.3 0.1 0.022 15.0 0.0 2.6 2 0 0 2 2 2 1 AAA domain Fer4_21 PF14697.6 AIN98155.1 - 0.00017 21.6 14.9 0.00039 20.5 14.9 1.6 1 0 0 1 1 1 1 4Fe-4S dicluster domain Rad17 PF03215.15 AIN98155.1 - 0.00064 19.7 0.0 0.21 11.5 0.0 2.5 2 0 0 2 2 2 1 Rad17 P-loop domain AAA PF00004.29 AIN98155.1 - 0.00079 19.9 0.3 0.045 14.2 0.0 2.7 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) RsgA_GTPase PF03193.16 AIN98155.1 - 0.00081 19.3 0.0 0.21 11.5 0.0 2.4 2 0 0 2 2 2 1 RsgA GTPase Fer4_7 PF12838.7 AIN98155.1 - 0.0012 19.4 0.2 0.0012 19.4 0.2 2.6 2 0 0 2 2 2 1 4Fe-4S dicluster domain AAA_28 PF13521.6 AIN98155.1 - 0.0015 18.8 0.0 3.4 7.9 0.0 2.8 3 0 0 3 3 3 2 AAA domain NACHT PF05729.12 AIN98155.1 - 0.0021 18.0 0.5 0.04 13.8 0.0 2.3 2 0 0 2 2 2 1 NACHT domain RNA_helicase PF00910.22 AIN98155.1 - 0.0023 18.3 0.0 0.67 10.4 0.0 3.0 3 0 0 3 3 2 1 RNA helicase Fer4_10 PF13237.6 AIN98155.1 - 0.0032 17.6 1.5 0.0032 17.6 1.5 2.3 1 1 1 2 2 2 2 4Fe-4S dicluster domain AAA_30 PF13604.6 AIN98155.1 - 0.0034 17.1 0.0 2.3 7.9 0.0 2.5 2 0 0 2 2 2 1 AAA domain TsaE PF02367.17 AIN98155.1 - 0.0064 16.5 0.1 0.027 14.5 0.0 1.9 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE SRP54 PF00448.22 AIN98155.1 - 0.0083 15.8 0.4 0.93 9.1 0.0 2.3 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain AAA_5 PF07728.14 AIN98155.1 - 0.0089 16.0 1.0 0.81 9.7 0.0 2.9 3 0 0 3 3 2 1 AAA domain (dynein-related subfamily) AAA_24 PF13479.6 AIN98155.1 - 0.012 15.3 0.1 1.4 8.6 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 AIN98155.1 - 0.021 14.4 0.1 0.78 9.2 0.0 2.5 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_33 PF13671.6 AIN98155.1 - 0.024 14.8 0.0 7.9 6.6 0.0 2.8 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 AIN98155.1 - 0.026 15.1 0.0 5.2 7.6 0.0 2.6 2 0 0 2 2 2 0 AAA domain Fer4_3 PF12798.7 AIN98155.1 - 0.031 15.2 4.0 0.031 15.2 4.0 2.7 2 0 0 2 2 1 0 4Fe-4S binding domain AAA_14 PF13173.6 AIN98155.1 - 0.042 13.9 0.0 1.3 9.1 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.6 AIN98155.1 - 0.047 13.3 0.1 8.1 6.0 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.6 AIN98155.1 - 0.06 13.7 0.2 1.9 8.8 0.0 2.6 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 AIN98155.1 - 0.065 13.3 0.0 11 6.2 0.0 2.7 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_27 PF13514.6 AIN98155.1 - 0.082 12.5 0.1 1 8.9 0.0 2.2 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 AIN98155.1 - 0.1 11.9 0.0 10 5.3 0.0 2.6 2 0 0 2 2 2 0 Zeta toxin Fer4_9 PF13187.6 AIN98155.1 - 0.11 12.7 14.6 0.32 11.2 14.7 1.8 1 1 0 1 1 1 0 4Fe-4S dicluster domain Stork_head PF10264.9 AIN98156.1 - 0.038 14.2 0.1 0.2 11.8 0.0 2.0 2 0 0 2 2 2 0 Winged helix Storkhead-box1 domain Hpt PF01627.23 AIN98156.1 - 0.1 12.9 0.9 0.2 11.9 0.1 1.9 2 0 0 2 2 2 0 Hpt domain P-mevalo_kinase PF04275.14 AIN98156.1 - 0.14 12.1 0.1 0.52 10.3 0.0 2.0 2 0 0 2 2 2 0 Phosphomevalonate kinase Leu_Phe_trans PF03588.14 AIN98157.1 - 0.00031 20.3 0.0 0.0093 15.5 0.1 2.7 2 1 0 2 2 2 1 Leucyl/phenylalanyl-tRNA protein transferase Ribosomal_L36e PF01158.18 AIN98158.1 - 1.3e-28 99.1 2.1 1.5e-28 98.9 2.1 1.0 1 0 0 1 1 1 1 Ribosomal protein L36e Corona_M PF01635.18 AIN98158.1 - 0.25 10.6 0.0 0.32 10.3 0.0 1.1 1 0 0 1 1 1 0 Coronavirus M matrix/glycoprotein DUF543 PF04418.12 AIN98159.1 - 4.2e-13 49.1 0.7 4.8e-13 48.9 0.7 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF543) DLH PF01738.18 AIN98159.1 - 0.025 14.1 0.1 0.025 14.1 0.1 1.1 1 0 0 1 1 1 0 Dienelactone hydrolase family ParA PF10609.9 AIN98159.1 - 0.036 13.5 0.0 0.054 12.9 0.0 1.3 1 1 0 1 1 1 0 NUBPL iron-transfer P-loop NTPase ATP-synt_C PF00137.21 AIN98160.1 - 1.3e-08 35.0 12.4 2.4e-08 34.2 12.4 1.4 1 0 0 1 1 1 1 ATP synthase subunit C PCI PF01399.27 AIN98162.1 - 2e-13 50.8 0.8 6e-13 49.2 0.1 2.3 2 0 0 2 2 2 1 PCI domain RPN5_C PF18098.1 AIN98162.1 - 5.1e-05 23.3 0.9 0.00027 21.0 0.4 2.4 2 0 0 2 2 2 1 26S proteasome regulatory subunit RPN5 C-terminal domain NPV_P10 PF05531.12 AIN98162.1 - 0.33 11.5 4.3 3.8 8.0 0.1 3.6 3 1 1 4 4 4 0 Nucleopolyhedrovirus P10 protein DUF4404 PF14357.6 AIN98162.1 - 0.66 10.6 0.1 0.66 10.6 0.1 3.9 4 1 0 4 4 4 0 Domain of unknown function (DUF4404) Vps39_1 PF10366.9 AIN98162.1 - 3.2 8.1 9.8 22 5.4 2.3 3.5 2 1 1 3 3 3 0 Vacuolar sorting protein 39 domain 1 DUF4509 PF14970.6 AIN98164.1 - 0.094 12.6 1.0 0.23 11.4 0.3 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4509) Ras PF00071.22 AIN98165.1 - 2.5e-45 154.0 0.0 3e-45 153.7 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 AIN98165.1 - 1.5e-33 115.6 0.0 2e-33 115.1 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 AIN98165.1 - 5.3e-10 39.0 0.0 9.7e-10 38.2 0.0 1.4 1 1 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 AIN98165.1 - 8.1e-06 25.5 0.0 2.9e-05 23.7 0.0 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 AIN98165.1 - 0.00018 21.0 0.0 0.00021 20.7 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 AIN98165.1 - 0.0003 20.7 0.0 0.038 13.9 0.0 2.1 2 0 0 2 2 2 1 RsgA GTPase MMR_HSR1 PF01926.23 AIN98165.1 - 0.0053 16.8 0.0 0.0084 16.2 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_25 PF13481.6 AIN98165.1 - 0.025 14.2 0.0 7.8 6.0 0.0 2.7 2 1 0 2 2 2 0 AAA domain Not1 PF04054.15 AIN98166.1 - 4.2e-94 315.5 5.7 4.2e-94 315.5 5.7 2.0 2 0 0 2 2 2 1 CCR4-Not complex component, Not1 CNOT1_CAF1_bind PF16415.5 AIN98166.1 - 9e-76 254.2 0.1 2.2e-75 252.9 0.1 1.7 2 0 0 2 2 2 1 CCR4-NOT transcription complex subunit 1 CAF1-binding domain CNOT1_TTP_bind PF16417.5 AIN98166.1 - 1.2e-45 155.0 0.0 5.2e-45 153.0 0.0 2.1 2 0 0 2 2 2 1 CCR4-NOT transcription complex subunit 1 TTP binding domain DUF3819 PF12842.7 AIN98166.1 - 8.4e-25 87.4 2.4 2.4e-24 85.9 0.4 2.7 2 0 0 2 2 2 1 Domain of unknown function (DUF3819) tRNA-synt_1g PF09334.11 AIN98167.1 - 9e-93 311.1 0.2 3.3e-92 309.3 0.2 1.7 1 1 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.22 AIN98167.1 - 1.5e-17 63.1 1.2 1.1e-08 33.9 1.3 3.1 2 1 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1e PF01406.19 AIN98167.1 - 4.9e-07 29.4 0.1 0.0016 17.8 0.1 2.2 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain MKT1_C PF12246.8 AIN98168.1 - 2.2e-14 53.3 0.0 3.9e-14 52.5 0.0 1.3 1 0 0 1 1 1 1 Temperature dependent protein affecting M2 dsRNA replication MKT1_N PF12247.8 AIN98168.1 - 2e-11 44.1 0.0 4e-11 43.1 0.0 1.6 1 0 0 1 1 1 1 Temperature dependent protein affecting M2 dsRNA replication Pkinase PF00069.25 AIN98169.1 - 1.1e-39 136.4 0.0 4.2e-35 121.4 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 AIN98169.1 - 7.3e-24 84.5 0.2 5.3e-14 52.1 0.0 3.3 3 0 0 3 3 3 3 Protein tyrosine kinase APH PF01636.23 AIN98169.1 - 0.0079 16.1 0.0 0.023 14.6 0.0 1.7 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 AIN98169.1 - 0.016 14.0 0.0 0.023 13.5 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase ATG16 PF08614.11 AIN98170.1 - 0.0036 17.5 7.3 0.0036 17.5 7.3 17.4 5 3 12 18 18 18 4 Autophagy protein 16 (ATG16) DUF4833 PF16117.5 AIN98172.1 - 4.1e-16 59.2 0.1 7.5e-07 29.2 0.0 3.1 2 1 0 2 2 2 2 Domain of unknown function (DUF4833) DUF4833 PF16117.5 AIN98173.1 - 1.3e-19 70.6 0.9 9.6e-10 38.6 0.1 3.1 2 1 0 2 2 2 2 Domain of unknown function (DUF4833) Peptidase_M24 PF00557.24 AIN98174.1 - 5.9e-41 140.5 0.1 8.2e-41 140.0 0.1 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 BAF1_ABF1 PF04684.13 AIN98174.1 - 0.15 11.1 3.4 0.27 10.3 3.4 1.3 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor HEXIM PF15313.6 AIN98175.1 - 0.0091 16.2 2.1 0.0091 16.2 2.1 2.1 2 0 0 2 2 2 1 Hexamethylene bis-acetamide-inducible protein DUF2730 PF10805.8 AIN98175.1 - 0.056 13.5 0.4 0.29 11.3 0.1 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF2730) MWFE PF15879.5 AIN98175.1 - 0.15 12.3 2.1 18 5.6 0.0 2.9 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase MWFE subunit Pribosyltran PF00156.27 AIN98176.1 - 5e-21 74.9 0.0 6.5e-21 74.5 0.0 1.1 1 0 0 1 1 1 1 Phosphoribosyl transferase domain Pribosyltran PF00156.27 AIN98177.1 - 4.9e-17 61.9 0.0 6.4e-17 61.5 0.0 1.2 1 0 0 1 1 1 1 Phosphoribosyl transferase domain KH_9 PF17904.1 AIN98177.1 - 0.18 12.2 0.0 0.74 10.2 0.0 2.0 3 0 0 3 3 3 0 FMRP KH0 domain Pkinase PF00069.25 AIN98178.1 - 5.2e-53 180.1 0.0 1.1e-36 126.6 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 AIN98178.1 - 8.9e-27 94.0 0.0 1.2e-17 64.1 0.0 2.6 2 1 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 AIN98178.1 - 3e-07 30.0 0.0 7.4e-07 28.8 0.0 1.5 1 1 0 1 1 1 1 Kinase-like BAG PF02179.16 AIN98179.1 - 0.00031 21.1 0.0 0.00046 20.6 0.0 1.4 1 0 0 1 1 1 1 BAG domain PUA PF01472.20 AIN98183.1 - 0.061 13.3 0.0 0.19 11.7 0.0 1.8 1 0 0 1 1 1 0 PUA domain HEAT PF02985.22 AIN98183.1 - 0.068 13.5 1.6 1.1 9.8 0.0 3.8 5 0 0 5 5 5 0 HEAT repeat HEAT_2 PF13646.6 AIN98183.1 - 0.19 12.1 2.5 0.43 11.0 1.1 2.4 2 0 0 2 2 2 0 HEAT repeats HEAT_EZ PF13513.6 AIN98183.1 - 0.63 10.6 3.9 1.9 9.1 0.3 3.1 2 0 0 2 2 2 0 HEAT-like repeat HEAT_2 PF13646.6 AIN98184.1 - 2e-10 40.9 1.2 0.004 17.5 0.0 4.5 3 1 1 4 4 4 3 HEAT repeats DUF4042 PF13251.6 AIN98184.1 - 2.7e-08 33.7 0.8 6.1e-05 22.8 0.1 4.5 4 1 0 4 4 4 1 Domain of unknown function (DUF4042) HEAT PF02985.22 AIN98184.1 - 2.7e-06 27.2 1.8 3 8.3 0.0 6.5 6 0 0 6 6 6 2 HEAT repeat HEAT_EZ PF13513.6 AIN98184.1 - 0.0045 17.5 0.4 0.0045 17.5 0.4 6.6 6 2 1 7 7 7 2 HEAT-like repeat Cnd1 PF12717.7 AIN98184.1 - 0.063 13.3 0.0 0.16 12.0 0.0 1.7 1 0 0 1 1 1 0 non-SMC mitotic condensation complex subunit 1 HEAT_PBS PF03130.16 AIN98184.1 - 0.99 10.3 4.2 13 6.8 0.0 4.4 4 1 0 4 4 4 0 PBS lyase HEAT-like repeat ABC2_membrane PF01061.24 AIN98185.1 - 2.2e-13 50.1 17.9 2.2e-13 50.1 17.9 2.1 2 0 0 2 2 2 1 ABC-2 type transporter ABC_tran PF00005.27 AIN98185.1 - 1.2e-08 35.6 0.0 2.1e-08 34.8 0.0 1.4 1 0 0 1 1 1 1 ABC transporter PDR_CDR PF06422.12 AIN98185.1 - 0.16 11.9 0.3 0.57 10.1 0.0 2.0 2 0 0 2 2 2 0 CDR ABC transporter ATP1G1_PLM_MAT8 PF02038.16 AIN98186.1 - 0.038 13.4 0.0 0.063 12.7 0.0 1.3 1 0 0 1 1 1 0 ATP1G1/PLM/MAT8 family DUF4499 PF14934.6 AIN98187.1 - 6.4e-07 29.6 2.9 1e-06 28.9 2.9 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4499) MutS_V PF00488.21 AIN98188.1 - 1.4e-31 110.0 0.0 3.4e-31 108.7 0.0 1.6 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 AIN98188.1 - 7.4e-18 65.5 0.0 8.4e-17 62.0 0.0 2.5 2 1 0 2 2 2 1 MutS domain III MutS_II PF05188.17 AIN98188.1 - 0.00066 20.0 0.1 0.0014 18.9 0.1 1.5 1 0 0 1 1 1 1 MutS domain II AAA_21 PF13304.6 AIN98188.1 - 0.0013 18.6 0.0 0.0027 17.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 AIN98188.1 - 0.0047 17.3 0.1 0.0047 17.3 0.1 3.0 4 0 0 4 4 4 1 AAA ATPase domain AAA_23 PF13476.6 AIN98188.1 - 0.026 15.0 0.4 0.054 14.0 0.4 1.4 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 AIN98188.1 - 0.049 14.1 0.2 0.12 12.9 0.2 1.6 1 0 0 1 1 1 0 ABC transporter AAA_14 PF13173.6 AIN98188.1 - 0.055 13.5 0.0 0.1 12.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 AIN98188.1 - 0.28 11.0 0.1 0.51 10.2 0.1 1.3 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea tRNA-synt_2 PF00152.20 AIN98189.1 - 9e-63 212.2 0.0 2e-62 211.1 0.0 1.5 1 1 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 AIN98189.1 - 5.3e-07 29.5 0.0 1e-06 28.6 0.0 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 AIN98189.1 - 2.7e-06 27.1 0.1 0.0052 16.3 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) Erythro_esteras PF05139.14 AIN98189.1 - 0.075 12.8 0.0 15 5.3 0.0 2.3 2 0 0 2 2 2 0 Erythromycin esterase tRNA_edit PF04073.15 AIN98192.1 - 4.9e-08 33.1 0.0 1.1e-07 31.9 0.0 1.6 1 1 0 1 1 1 1 Aminoacyl-tRNA editing domain DUF5473 PF17567.2 AIN98192.1 - 0.021 15.1 0.8 0.021 15.1 0.8 2.6 2 1 1 3 3 3 0 Family of unknown function (DUF5473) Sugarporin_N PF11471.8 AIN98192.1 - 0.095 12.7 4.0 0.15 12.0 2.5 2.1 1 1 0 1 1 1 0 Maltoporin periplasmic N-terminal extension DUF3138 PF11336.8 AIN98192.1 - 0.34 9.5 1.4 0.46 9.0 1.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) PDCD2_C PF04194.13 AIN98194.1 - 7e-28 97.9 0.1 7e-28 97.9 0.1 2.0 2 1 0 2 2 2 1 Programmed cell death protein 2, C-terminal putative domain Vps4_C PF09336.10 AIN98194.1 - 0.11 12.5 0.2 0.27 11.3 0.2 1.6 1 0 0 1 1 1 0 Vps4 C terminal oligomerisation domain Methyltransf_2 PF00891.18 AIN98195.1 - 0.0054 16.0 0.1 0.012 14.9 0.1 1.5 1 0 0 1 1 1 1 O-methyltransferase domain Bim_N PF06773.11 AIN98195.1 - 0.012 15.2 0.3 0.062 13.0 0.3 2.3 1 0 0 1 1 1 0 Bim protein N-terminus SET PF00856.28 AIN98196.1 - 0.14 12.5 0.0 0.5 10.7 0.0 1.8 1 1 0 1 1 1 0 SET domain Clathrin PF00637.20 AIN98197.1 - 4.7e-15 55.7 18.4 0.0059 16.5 0.0 10.7 8 3 3 12 12 12 3 Region in Clathrin and VPS ANAPC4_WD40 PF12894.7 AIN98197.1 - 7.4e-09 35.8 0.0 0.036 14.4 0.0 4.4 2 1 2 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 AIN98197.1 - 2.3e-06 28.2 2.6 1.1 10.2 0.1 5.7 5 0 0 5 5 5 1 WD domain, G-beta repeat PPR PF01535.20 AIN98197.1 - 0.00022 21.3 7.9 0.64 10.4 0.1 7.7 6 1 1 7 7 7 1 PPR repeat ANAPC3 PF12895.7 AIN98197.1 - 0.00053 20.2 12.8 0.017 15.4 0.0 6.5 6 1 1 7 7 6 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.6 AIN98197.1 - 0.00072 19.4 26.7 2.9 8.1 0.0 12.1 13 3 0 13 13 12 1 Tetratricopeptide repeat Coatomer_WDAD PF04053.14 AIN98197.1 - 0.0011 18.1 9.8 0.11 11.5 0.1 5.4 4 2 2 6 6 6 2 Coatomer WD associated region TPR_11 PF13414.6 AIN98197.1 - 0.0042 16.7 8.8 10 5.9 0.1 6.2 5 0 0 5 5 5 0 TPR repeat TPR_1 PF00515.28 AIN98197.1 - 0.0052 16.6 34.4 6.3 6.8 0.1 10.8 10 1 1 11 11 11 1 Tetratricopeptide repeat PPR_2 PF13041.6 AIN98197.1 - 0.021 15.0 2.7 1.1 9.5 0.1 5.0 5 0 0 5 5 5 0 PPR repeat family TPR_2 PF07719.17 AIN98197.1 - 0.024 14.7 46.2 0.27 11.5 0.0 12.2 14 1 1 15 15 12 0 Tetratricopeptide repeat PTAC PF06130.12 AIN98197.1 - 0.039 14.1 0.0 0.12 12.5 0.0 1.9 1 0 0 1 1 1 0 Phosphate propanoyltransferase TPR_17 PF13431.6 AIN98197.1 - 0.05 14.0 0.6 3.7 8.1 0.1 4.1 3 0 0 3 3 2 0 Tetratricopeptide repeat TPR_4 PF07721.14 AIN98197.1 - 0.055 14.1 15.4 1.1 10.0 0.0 8.9 10 1 1 11 11 9 0 Tetratricopeptide repeat TPR_14 PF13428.6 AIN98197.1 - 0.061 14.2 45.2 12 7.1 0.1 15.3 12 6 2 15 15 14 0 Tetratricopeptide repeat DUF410 PF04190.13 AIN98197.1 - 0.22 11.3 8.3 0.35 10.6 0.0 4.0 4 1 1 5 5 5 0 Protein of unknown function (DUF410) C1_1 PF00130.22 AIN98197.1 - 0.27 11.1 1.7 0.6 10.0 1.7 1.5 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) PPR_1 PF12854.7 AIN98197.1 - 0.38 10.5 2.3 0.54 10.0 0.3 2.5 2 0 0 2 2 2 0 PPR repeat TPR_12 PF13424.6 AIN98197.1 - 0.65 10.3 31.7 2.5 8.5 0.1 10.6 11 0 0 11 11 11 0 Tetratricopeptide repeat TPR_19 PF14559.6 AIN98197.1 - 0.74 10.4 18.3 1.6 9.3 0.0 7.8 7 2 2 9 9 8 0 Tetratricopeptide repeat TPR_8 PF13181.6 AIN98197.1 - 1.1 9.7 29.1 22 5.6 0.1 9.4 11 0 0 11 11 8 0 Tetratricopeptide repeat Pep3_Vps18 PF05131.14 AIN98197.1 - 4.2 7.2 6.9 61 3.4 0.1 4.9 6 0 0 6 6 5 0 Pep3/Vps18/deep orange family TetR_C_24 PF17932.1 AIN98199.1 - 0.28 11.5 1.6 0.66 10.3 0.2 2.2 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain Lzipper-MIP1 PF14389.6 AIN98199.1 - 0.53 10.6 3.7 0.51 10.7 0.4 2.8 2 0 0 2 2 2 0 Leucine-zipper of ternary complex factor MIP1 Tubulin PF00091.25 AIN98200.1 - 3.3e-62 210.2 0.0 4.5e-62 209.8 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 AIN98200.1 - 5.7e-21 75.0 0.0 1e-20 74.2 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_2 PF13809.6 AIN98200.1 - 7.8e-06 25.3 0.0 1.2e-05 24.7 0.0 1.2 1 0 0 1 1 1 1 Tubulin like Misat_Tub_SegII PF10644.9 AIN98200.1 - 0.15 12.3 0.0 0.28 11.5 0.0 1.4 1 0 0 1 1 1 0 Misato Segment II tubulin-like domain Bombesin PF02044.17 AIN98200.1 - 0.17 12.0 1.2 0.36 11.0 1.2 1.5 1 0 0 1 1 1 0 Bombesin-like peptide Ax_dynein_light PF10211.9 AIN98201.1 - 1.2e-48 165.5 3.2 1.7e-48 165.0 3.2 1.2 1 0 0 1 1 1 1 Axonemal dynein light chain Borrelia_P83 PF05262.11 AIN98202.1 - 0.011 14.3 5.0 0.015 13.8 5.0 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein Kinesin PF00225.23 AIN98203.1 - 8.8e-85 284.6 0.3 1.5e-84 283.8 0.3 1.3 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 AIN98203.1 - 2.3e-13 50.3 0.0 6.4e-13 48.9 0.0 1.8 1 0 0 1 1 1 1 Microtubule binding Syntaxin-6_N PF09177.11 AIN98203.1 - 0.22 12.1 17.5 0.016 15.8 4.0 4.3 3 0 0 3 3 3 0 Syntaxin 6, N-terminal Pox_A_type_inc PF04508.12 AIN98203.1 - 0.24 11.3 6.3 1.8 8.5 6.3 2.6 1 0 0 1 1 1 0 Viral A-type inclusion protein repeat KIAA1430 PF13879.6 AIN98203.1 - 1.9 9.3 16.5 0.11 13.3 1.2 4.4 4 1 0 4 4 4 0 KIAA1430 homologue DUF3153 PF11353.8 AIN98203.1 - 6.4 6.3 8.4 0.65 9.5 1.5 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3153) Ribosomal_L6 PF00347.23 AIN98204.1 - 3.2e-25 88.6 2.5 4.6e-14 52.8 0.4 2.1 2 0 0 2 2 2 2 Ribosomal protein L6 Glyco_hydro_65C PF03633.15 AIN98204.1 - 0.06 13.3 0.2 5.8 6.9 0.1 3.0 3 1 0 3 3 3 0 Glycosyl hydrolase family 65, C-terminal domain Ribosom_S12_S23 PF00164.25 AIN98205.1 - 3.2e-48 162.1 0.4 3.2e-48 162.1 0.4 1.5 2 0 0 2 2 2 1 Ribosomal protein S12/S23 Ribosom_S12_S23 PF00164.25 AIN98206.1 - 3.2e-48 162.1 0.4 3.2e-48 162.1 0.4 1.5 2 0 0 2 2 2 1 Ribosomal protein S12/S23 Pkinase PF00069.25 AIN98207.1 - 3.9e-73 246.1 0.0 4.6e-73 245.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 AIN98207.1 - 6.5e-34 117.4 0.0 8.3e-34 117.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 AIN98207.1 - 0.00094 19.2 0.7 0.014 15.3 0.4 2.1 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kinase-like PF14531.6 AIN98207.1 - 0.0018 17.6 0.0 0.038 13.3 0.0 2.1 1 1 1 2 2 2 1 Kinase-like Kdo PF06293.14 AIN98207.1 - 0.0086 15.4 0.6 0.017 14.5 0.6 1.4 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 AIN98207.1 - 0.086 11.8 0.0 10 4.9 0.0 2.1 2 0 0 2 2 2 0 Haspin like kinase domain Cpn60_TCP1 PF00118.24 AIN98208.1 - 4.5e-142 474.1 9.2 5.5e-142 473.9 9.2 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Colicin PF01024.19 AIN98208.1 - 0.026 14.4 0.1 0.13 12.2 0.1 2.0 2 0 0 2 2 2 0 Colicin pore forming domain Sde2_N_Ubi PF13019.6 AIN98208.1 - 0.19 11.6 1.4 0.54 10.1 1.4 1.7 1 0 0 1 1 1 0 Silencing defective 2 N-terminal ubiquitin domain Tau95 PF09734.9 AIN98209.1 - 1.8e-20 74.2 0.0 3.3e-20 73.3 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase III transcription factor (TF)IIIC subunit HTH domain Tau95_N PF17682.1 AIN98209.1 - 0.0031 17.7 0.1 1.2 9.3 0.0 2.9 4 0 0 4 4 4 2 Tau95 Triple barrel domain IQ PF00612.27 AIN98210.1 - 1.8e-14 52.1 197.1 0.00019 20.9 0.0 23.9 26 1 1 27 27 27 14 IQ calmodulin-binding motif TPR_1 PF00515.28 AIN98210.1 - 1.7e-05 24.4 0.0 1.5 8.8 0.0 4.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 AIN98210.1 - 0.00082 19.6 0.7 0.00082 19.6 0.7 6.0 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_10 PF13374.6 AIN98210.1 - 0.0086 15.9 0.1 0.0086 15.9 0.1 6.9 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_2 PF07719.17 AIN98210.1 - 0.15 12.3 3.4 3.4 8.0 0.1 4.7 4 0 0 4 4 4 0 Tetratricopeptide repeat SesA PF17107.5 AIN98210.1 - 3.1 8.0 9.6 6.1 7.1 0.3 3.9 3 0 0 3 3 3 0 N-terminal domain on NACHT_NTPase and P-loop NTPases WD40 PF00400.32 AIN98211.1 - 9.3e-16 57.9 7.8 0.06 14.2 0.0 6.8 6 0 0 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 AIN98211.1 - 4.6e-05 23.6 0.0 11 6.4 0.0 4.3 4 1 1 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Nbas_N PF15492.6 AIN98211.1 - 0.0015 17.9 0.2 0.044 13.1 0.2 2.5 1 1 0 2 2 2 1 Neuroblastoma-amplified sequence, N terminal Nup160 PF11715.8 AIN98211.1 - 0.0078 14.9 0.1 0.02 13.6 0.0 1.6 2 0 0 2 2 2 1 Nucleoporin Nup120/160 RAB3GAP2_N PF14655.6 AIN98211.1 - 0.14 11.4 0.0 6.2 6.0 0.0 2.7 2 0 0 2 2 2 0 Rab3 GTPase-activating protein regulatory subunit N-terminus Golgin_A5 PF09787.9 AIN98212.1 - 0.0085 15.6 0.0 0.0085 15.6 0.0 4.0 2 1 1 4 4 4 2 Golgin subfamily A member 5 AAA PF00004.29 AIN98212.1 - 0.062 13.7 0.1 0.16 12.4 0.1 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) bZIP_1 PF00170.21 AIN98212.1 - 0.5 10.5 9.9 7.9 6.7 0.1 4.0 3 1 0 3 3 3 0 bZIP transcription factor SHE3 PF17078.5 AIN98212.1 - 2.1 8.0 18.2 1.4 8.6 1.5 2.7 3 0 0 3 3 3 0 SWI5-dependent HO expression protein 3 ATG16 PF08614.11 AIN98212.1 - 7.1 6.8 43.7 0.44 10.7 9.5 3.2 1 1 2 3 3 3 0 Autophagy protein 16 (ATG16) LRR_8 PF13855.6 AIN98216.1 - 5.7e-27 93.3 10.7 1.5e-07 31.1 1.2 5.3 1 1 6 7 7 7 6 Leucine rich repeat LRR_4 PF12799.7 AIN98216.1 - 9.7e-18 64.0 12.5 0.00043 20.6 0.3 6.7 3 2 3 8 8 8 7 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 AIN98216.1 - 1.2e-09 37.4 4.9 3.9 8.4 0.0 8.9 11 0 0 11 11 11 2 Leucine Rich Repeat LRR_6 PF13516.6 AIN98216.1 - 0.033 14.2 19.1 14 6.0 0.0 8.0 9 0 0 9 9 9 0 Leucine Rich repeat Ribosomal_L1 PF00687.21 AIN98217.1 - 2.2e-09 37.4 0.0 0.00016 21.5 0.0 2.1 2 0 0 2 2 2 2 Ribosomal protein L1p/L10e family PIF1 PF05970.14 AIN98218.1 - 7.8e-34 117.4 0.1 4e-24 85.5 0.0 3.7 2 1 1 3 3 3 3 PIF1-like helicase AAA_30 PF13604.6 AIN98218.1 - 1.5e-14 54.2 0.3 1.2e-12 48.0 0.3 2.7 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 AIN98218.1 - 2e-10 41.2 0.1 8.1e-10 39.2 0.1 2.1 1 1 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 AIN98218.1 - 2.2e-06 27.6 0.1 0.21 11.3 0.0 3.4 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase DEAD PF00270.29 AIN98218.1 - 1.8e-05 24.6 0.0 0.00077 19.3 0.0 2.5 1 1 0 1 1 1 1 DEAD/DEAH box helicase UvrD-helicase PF00580.21 AIN98218.1 - 0.0035 16.9 0.0 0.0058 16.2 0.0 1.3 1 0 0 1 1 1 1 UvrD/REP helicase N-terminal domain AAA_5 PF07728.14 AIN98218.1 - 0.0059 16.6 0.0 0.49 10.4 0.0 2.4 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_32 PF13654.6 AIN98218.1 - 0.0059 15.4 0.0 0.0088 14.9 0.0 1.1 1 0 0 1 1 1 1 AAA domain UvrD_C_2 PF13538.6 AIN98218.1 - 0.0081 16.0 0.0 0.018 14.9 0.0 1.6 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_16 PF13191.6 AIN98218.1 - 0.0096 16.3 0.2 0.026 14.9 0.2 1.8 1 1 0 1 1 1 1 AAA ATPase domain Mg_chelatase PF01078.21 AIN98218.1 - 0.012 15.0 0.2 0.023 14.1 0.2 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI NTPase_1 PF03266.15 AIN98218.1 - 0.016 15.1 0.0 0.036 14.0 0.0 1.5 1 0 0 1 1 1 0 NTPase AAA_11 PF13086.6 AIN98218.1 - 0.03 14.1 2.3 0.16 11.7 0.0 2.6 3 0 0 3 3 3 0 AAA domain PhoH PF02562.16 AIN98218.1 - 0.045 13.2 0.0 0.082 12.3 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein AAA_24 PF13479.6 AIN98218.1 - 0.045 13.5 0.0 0.24 11.1 0.0 2.0 1 1 0 1 1 1 0 AAA domain AAA_7 PF12775.7 AIN98218.1 - 0.088 12.3 0.1 0.95 9.0 0.0 2.1 2 0 0 2 2 2 0 P-loop containing dynein motor region DUF2075 PF09848.9 AIN98218.1 - 0.11 11.7 0.0 0.19 11.0 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Herpes_Helicase PF02689.14 AIN98218.1 - 0.11 10.4 0.2 0.69 7.8 0.0 2.1 3 0 0 3 3 3 0 Helicase ERM PF00769.19 AIN98219.1 - 0.024 14.5 0.0 0.04 13.7 0.0 1.4 1 0 0 1 1 1 0 Ezrin/radixin/moesin family Ribosomal_L29 PF00831.23 AIN98219.1 - 0.19 11.7 0.2 0.19 11.7 0.2 2.2 2 0 0 2 2 2 0 Ribosomal L29 protein TK PF00265.18 AIN98220.1 - 1.6e-61 207.2 1.0 2.3e-61 206.7 1.0 1.2 1 0 0 1 1 1 1 Thymidine kinase AAA_14 PF13173.6 AIN98220.1 - 0.0011 18.9 0.0 0.0024 17.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain TFIIB_C_1 PF18542.1 AIN98220.1 - 0.048 13.7 0.2 0.15 12.1 0.1 1.9 2 0 0 2 2 2 0 Transcription factor IIB C-terminal module 1 PKcGMP_CC PF16808.5 AIN98221.1 - 0.028 14.3 16.9 0.18 11.7 0.3 6.5 5 2 1 6 6 6 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Pox_A_type_inc PF04508.12 AIN98221.1 - 2.1 8.3 8.8 0.32 10.9 1.8 3.2 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat WD40 PF00400.32 AIN98222.1 - 8.5e-11 42.2 0.7 1.2e-06 29.1 0.2 5.0 6 0 0 6 6 6 2 WD domain, G-beta repeat RNR_N PF08343.10 AIN98222.1 - 0.12 12.4 0.0 28 4.8 0.0 2.5 2 0 0 2 2 2 0 Ribonucleotide reductase N-terminal ADK PF00406.22 AIN98223.1 - 1.6e-37 129.0 0.0 2.3e-37 128.4 0.0 1.2 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 AIN98223.1 - 1.4e-17 64.4 0.1 2.8e-17 63.4 0.0 1.5 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 AIN98223.1 - 1e-05 26.1 0.0 8.3e-05 23.1 0.0 2.3 2 1 0 2 2 2 1 AAA domain ADK_lid PF05191.14 AIN98223.1 - 0.015 15.3 0.1 0.06 13.3 0.0 2.1 2 1 0 2 2 2 0 Adenylate kinase, active site lid AAA_33 PF13671.6 AIN98223.1 - 0.022 14.9 0.0 0.048 13.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain LRR_6 PF13516.6 AIN98224.1 - 1.7e-06 27.6 0.6 0.27 11.4 0.3 3.5 3 0 0 3 3 3 3 Leucine Rich repeat LRR_1 PF00560.33 AIN98224.1 - 0.32 11.7 1.7 45 5.2 0.0 3.1 3 0 0 3 3 3 0 Leucine Rich Repeat Serine_rich PF08824.10 AIN98225.1 - 0.0079 16.2 0.0 0.024 14.7 0.0 1.7 1 0 0 1 1 1 1 Serine rich protein interaction domain Mito_fiss_reg PF05308.11 AIN98225.1 - 0.062 13.4 0.2 0.11 12.5 0.2 1.3 1 0 0 1 1 1 0 Mitochondrial fission regulator SelR PF01641.18 AIN98226.1 - 0.0074 16.4 0.1 1.7 8.8 0.0 2.6 2 1 0 2 2 2 2 SelR domain Synaptobrevin PF00957.21 AIN98227.1 - 1.3e-25 89.0 1.1 1.9e-25 88.5 1.1 1.2 1 0 0 1 1 1 1 Synaptobrevin NMO PF03060.15 AIN98228.1 - 3.1e-61 207.6 1.0 3.8e-40 138.3 0.9 2.0 1 1 1 2 2 2 2 Nitronate monooxygenase IMPDH PF00478.25 AIN98228.1 - 1.6e-10 40.5 0.3 9.1e-09 34.8 0.3 2.2 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.18 AIN98228.1 - 6.3e-10 38.6 0.4 1.1e-09 37.9 0.4 1.3 1 0 0 1 1 1 1 FMN-dependent dehydrogenase DHO_dh PF01180.21 AIN98228.1 - 1.9e-07 30.6 0.2 7.7e-07 28.6 0.2 1.8 2 0 0 2 2 2 1 Dihydroorotate dehydrogenase ThiG PF05690.14 AIN98228.1 - 4e-05 23.1 0.6 6.6e-05 22.3 0.6 1.3 1 0 0 1 1 1 1 Thiazole biosynthesis protein ThiG Glu_synthase PF01645.17 AIN98228.1 - 0.002 17.4 2.5 0.0039 16.4 2.5 1.5 1 1 0 1 1 1 1 Conserved region in glutamate synthase Dus PF01207.17 AIN98228.1 - 0.0091 15.1 0.1 0.027 13.6 0.0 1.8 2 0 0 2 2 2 1 Dihydrouridine synthase (Dus) NanE PF04131.14 AIN98228.1 - 0.033 13.4 0.1 0.057 12.6 0.1 1.3 1 0 0 1 1 1 0 Putative N-acetylmannosamine-6-phosphate epimerase His_biosynth PF00977.21 AIN98228.1 - 0.046 13.2 0.1 0.076 12.5 0.1 1.4 1 0 0 1 1 1 0 Histidine biosynthesis protein zf-RING_2 PF13639.6 AIN98229.1 - 6e-09 36.1 3.8 4.4e-07 30.1 1.3 2.3 2 0 0 2 2 2 2 Ring finger domain zf-rbx1 PF12678.7 AIN98229.1 - 3.5e-08 33.6 1.1 5.7e-07 29.7 0.5 2.2 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-RING_11 PF17123.5 AIN98229.1 - 7.1e-07 28.9 1.3 0.0073 16.0 0.2 2.4 2 0 0 2 2 2 2 RING-like zinc finger zf-C3HC4_2 PF13923.6 AIN98229.1 - 8.5e-07 28.7 4.5 1.4e-06 28.0 0.8 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 AIN98229.1 - 5.7e-06 26.1 2.4 1.8e-05 24.5 0.2 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 AIN98229.1 - 0.00015 21.7 0.4 0.00031 20.7 0.4 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.6 AIN98229.1 - 0.044 13.7 3.0 0.16 11.9 0.7 2.1 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 AIN98229.1 - 0.11 12.6 7.6 0.3 11.1 1.5 3.0 2 1 1 3 3 3 0 RING-type zinc-finger IGPD PF00475.18 AIN98229.1 - 0.13 12.6 0.0 0.22 11.8 0.0 1.3 1 0 0 1 1 1 0 Imidazoleglycerol-phosphate dehydratase zf-RING_5 PF14634.6 AIN98229.1 - 0.32 11.0 2.0 1.1 9.3 0.7 2.1 2 0 0 2 2 2 0 zinc-RING finger domain zf-RING_4 PF14570.6 AIN98229.1 - 1.5 8.7 3.7 0.35 10.7 0.5 1.6 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-C3HC4_4 PF15227.6 AIN98229.1 - 2.7 8.2 5.3 0.41 10.8 1.0 1.8 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING RF-1 PF00472.20 AIN98230.1 - 5.2e-09 36.1 0.8 5.2e-09 36.1 0.8 4.1 4 1 1 5 5 5 1 RF-1 domain DUF3818 PF12825.7 AIN98230.1 - 0.095 11.7 6.6 1.7 7.6 7.5 2.1 2 0 0 2 2 2 0 Domain of unknown function in PX-proteins (DUF3818) DUF4250 PF14056.6 AIN98230.1 - 0.15 12.0 0.1 0.15 12.0 0.1 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4250) DUF812 PF05667.11 AIN98230.1 - 0.28 10.0 16.4 0.14 11.0 13.8 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF812) Sigma70_ner PF04546.13 AIN98230.1 - 0.72 9.7 11.4 0.22 11.4 0.4 2.8 2 0 0 2 2 2 0 Sigma-70, non-essential region Prominin PF05478.11 AIN98230.1 - 1.9 6.4 5.4 3.5 5.5 5.4 1.3 1 0 0 1 1 1 0 Prominin YabA PF06156.13 AIN98230.1 - 1.9 9.2 13.9 50 4.6 9.6 3.6 2 1 0 2 2 2 0 Initiation control protein YabA LMBR1 PF04791.16 AIN98230.1 - 2.5 6.9 3.0 4.8 6.0 3.0 1.5 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF4044 PF13253.6 AIN98232.1 - 1.4 8.5 3.2 2.3 7.8 3.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4044) SMC_N PF02463.19 AIN98233.1 - 1.1e-70 237.5 5.5 9.6e-35 120.0 1.0 3.1 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 AIN98233.1 - 2.4e-20 73.0 0.3 1.6e-19 70.3 0.0 2.7 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.6 AIN98233.1 - 2.5e-12 47.2 1.4 3.2e-05 23.9 0.1 3.2 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 AIN98233.1 - 1.7e-05 24.5 0.0 3.3e-05 23.5 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_15 PF13175.6 AIN98233.1 - 0.00012 21.9 10.9 0.00012 21.9 10.9 4.1 3 1 0 3 3 3 1 AAA ATPase domain Spc7 PF08317.11 AIN98233.1 - 0.0011 18.0 14.6 0.0011 18.0 14.6 6.4 2 2 5 7 7 7 2 Spc7 kinetochore protein DUF5398 PF17376.2 AIN98233.1 - 0.054 14.1 0.2 0.054 14.1 0.2 3.3 2 1 0 2 2 2 0 Family of unknown function (DUF5398) ABC_tran PF00005.27 AIN98233.1 - 0.11 13.0 0.0 0.11 13.0 0.0 5.1 4 2 0 4 4 4 0 ABC transporter AAA_22 PF13401.6 AIN98233.1 - 1 9.6 0.0 1 9.6 0.0 4.7 5 2 1 6 6 6 0 AAA domain CARD PF00619.21 AIN98233.1 - 7.1 6.7 10.7 3.9 7.6 0.0 4.1 4 0 0 4 4 4 0 Caspase recruitment domain V-ATPase_H_N PF03224.14 AIN98234.1 - 1.1e-66 225.3 0.6 1.7e-66 224.6 0.6 1.2 1 0 0 1 1 1 1 V-ATPase subunit H V-ATPase_H_C PF11698.8 AIN98234.1 - 4.2e-37 126.8 0.1 1.6e-36 125.0 0.0 1.9 2 0 0 2 2 2 1 V-ATPase subunit H RACo_linker PF17650.1 AIN98234.1 - 0.14 12.0 0.0 0.36 10.7 0.0 1.7 1 0 0 1 1 1 0 RACo linker region PB1 PF00564.24 AIN98235.1 - 4.4e-07 29.8 0.0 1e-06 28.6 0.0 1.6 1 0 0 1 1 1 1 PB1 domain DHHC PF01529.20 AIN98239.1 - 9.8e-32 109.9 3.4 9.8e-32 109.9 3.4 1.8 2 1 0 2 2 2 1 DHHC palmitoyltransferase DUF588 PF04535.12 AIN98239.1 - 0.06 13.1 1.5 0.14 12.0 1.5 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF588) Herpes_UL73 PF03554.13 AIN98239.1 - 5.6 7.0 9.4 0.11 12.5 0.8 2.3 2 0 0 2 2 2 0 UL73 viral envelope glycoprotein DUF971 PF06155.12 AIN98240.1 - 2.5e-15 56.9 0.0 5.3e-13 49.4 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF971) DUF393 PF04134.12 AIN98241.1 - 0.0022 19.3 2.2 0.074 14.4 0.7 2.9 2 1 0 2 2 2 1 Protein of unknown function, DUF393 Phage_lysis PF03245.13 AIN98241.1 - 0.049 13.8 2.3 0.075 13.2 1.5 1.6 2 0 0 2 2 2 0 Bacteriophage Rz lysis protein E1_dh PF00676.20 AIN98242.1 - 5.6e-79 265.2 0.0 8.1e-79 264.7 0.0 1.1 1 0 0 1 1 1 1 Dehydrogenase E1 component Cyt-b5 PF00173.28 AIN98243.1 - 2.9e-05 24.1 0.0 0.00012 22.1 0.0 2.1 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain PRMT5 PF05185.16 AIN98244.1 - 3.6e-39 134.4 0.0 6.2e-39 133.6 0.0 1.3 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase PRMT5_C PF17286.2 AIN98244.1 - 2.2e-23 83.0 0.0 3.7e-23 82.3 0.0 1.3 1 0 0 1 1 1 1 PRMT5 oligomerisation domain MIT PF04212.18 AIN98246.1 - 0.0006 19.8 2.3 0.014 15.4 0.1 2.6 2 0 0 2 2 2 1 MIT (microtubule interacting and transport) domain TPR_12 PF13424.6 AIN98246.1 - 0.022 15.0 9.0 4.6 7.6 0.4 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat DNA_pol_lambd_f PF10391.9 AIN98246.1 - 0.023 14.5 0.0 2.7 7.9 0.0 2.6 2 0 0 2 2 2 0 Fingers domain of DNA polymerase lambda TPR_8 PF13181.6 AIN98246.1 - 0.028 14.6 3.3 14 6.2 0.7 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_2 PF07719.17 AIN98246.1 - 0.031 14.4 5.7 0.075 13.2 0.5 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.28 AIN98246.1 - 0.26 11.2 6.3 0.6 10.0 1.8 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.6 AIN98246.1 - 0.62 10.8 5.4 34 5.3 0.8 4.5 4 0 0 4 4 4 0 Tetratricopeptide repeat MAM33 PF02330.16 AIN98247.1 - 0.069 13.1 0.5 0.14 12.0 0.5 1.4 1 0 0 1 1 1 0 Mitochondrial glycoprotein Mut7-C PF01927.16 AIN98250.1 - 0.011 15.8 0.0 1.2 9.3 0.0 2.7 2 0 0 2 2 2 0 Mut7-C RNAse domain HMG_box PF00505.19 AIN98251.1 - 3.9e-05 24.0 2.9 0.0021 18.4 0.2 3.2 4 0 0 4 4 4 1 HMG (high mobility group) box HMG_box_2 PF09011.10 AIN98251.1 - 6.8e-05 23.4 3.6 0.031 14.9 0.5 3.0 3 0 0 3 3 3 2 HMG-box domain Mrpl_C PF18502.1 AIN98251.1 - 0.072 13.4 0.0 0.11 12.8 0.0 1.4 1 0 0 1 1 1 0 54S ribosomal protein L8 C-terminal domain Sec8_exocyst PF04048.14 AIN98252.1 - 4.2e-11 42.9 0.2 1e-10 41.7 0.2 1.6 1 0 0 1 1 1 1 Sec8 exocyst complex component specific domain Zw10 PF06248.13 AIN98252.1 - 0.00035 19.3 0.8 0.00065 18.4 0.8 1.3 1 0 0 1 1 1 1 Centromere/kinetochore Zw10 Vps54_N PF10475.9 AIN98252.1 - 0.0017 17.7 0.4 0.0033 16.8 0.4 1.5 1 0 0 1 1 1 1 Vacuolar-sorting protein 54, of GARP complex Cwf_Cwc_15 PF04889.12 AIN98252.1 - 0.2 11.4 7.6 0.48 10.1 7.6 1.6 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein FAM176 PF14851.6 AIN98252.1 - 0.34 10.6 8.3 6.9 6.3 6.3 2.7 2 0 0 2 2 2 0 FAM176 family Nop14 PF04147.12 AIN98252.1 - 0.43 8.7 12.7 0.74 8.0 12.7 1.2 1 0 0 1 1 1 0 Nop14-like family Prothymosin PF03247.14 AIN98252.1 - 4.9 7.7 27.9 1.2 9.6 21.7 2.6 2 0 0 2 2 2 0 Prothymosin/parathymosin family Ribosomal_S17_N PF16205.5 AIN98253.1 - 1.2e-27 96.1 0.7 1.2e-27 96.1 0.7 1.6 2 0 0 2 2 2 1 Ribosomal_S17 N-terminal Ribosomal_S17 PF00366.20 AIN98253.1 - 3.5e-22 78.3 0.5 3.5e-22 78.3 0.5 1.9 2 0 0 2 2 2 1 Ribosomal protein S17 DUF4018 PF13210.6 AIN98254.1 - 0.0078 16.0 0.2 0.014 15.2 0.2 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4018) Sigma_reg_N PF13800.6 AIN98254.1 - 2.9 8.2 5.9 3.1 8.2 0.3 2.8 3 0 0 3 3 3 0 Sigma factor regulator N-terminal DEAD PF00270.29 AIN98255.1 - 6.7e-37 126.9 0.3 8.7e-36 123.3 0.1 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 AIN98255.1 - 7.5e-26 90.7 0.8 2.7e-25 88.9 0.2 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 AIN98255.1 - 2.7e-09 37.3 0.0 5.4e-09 36.3 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CMS1 PF14617.6 AIN98255.1 - 0.0037 16.6 2.1 0.027 13.8 0.0 3.1 2 1 1 4 4 4 1 U3-containing 90S pre-ribosomal complex subunit DUF4844 PF16133.5 AIN98255.1 - 0.061 13.9 0.6 0.061 13.9 0.6 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4844) LETM1 PF07766.13 AIN98256.1 - 0.001 18.4 0.1 0.0024 17.3 0.1 1.6 2 1 0 2 2 2 1 LETM1-like protein Tn7_Tnp_TnsA_N PF08722.11 AIN98256.1 - 0.047 13.9 0.1 0.11 12.7 0.1 1.6 1 0 0 1 1 1 0 TnsA endonuclease N terminal GST_C_6 PF17171.4 AIN98257.1 - 5.6e-08 32.5 0.0 1.6e-07 31.0 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 AIN98257.1 - 0.00013 21.9 0.6 0.0003 20.7 0.0 1.9 2 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain COG6 PF06419.11 AIN98258.1 - 0.17 10.0 0.0 0.23 9.6 0.0 1.1 1 0 0 1 1 1 0 Conserved oligomeric complex COG6 GMC_oxred_N PF00732.19 AIN98259.1 - 2.5e-12 46.8 0.0 3.4e-12 46.3 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 AIN98259.1 - 1.4e-11 45.1 0.1 1.2e-10 42.1 0.0 2.3 2 1 0 2 2 2 1 GMC oxidoreductase Pyr_redox_2 PF07992.14 AIN98259.1 - 0.00077 18.8 0.1 0.094 11.9 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 AIN98259.1 - 0.0017 18.5 1.4 0.003 17.7 0.3 2.1 2 1 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 AIN98259.1 - 0.0024 17.0 0.0 0.013 14.6 0.0 2.1 3 0 0 3 3 3 1 Lycopene cyclase protein HI0933_like PF03486.14 AIN98259.1 - 0.0029 16.4 0.2 0.0041 15.9 0.2 1.2 1 0 0 1 1 1 1 HI0933-like protein FAD_binding_2 PF00890.24 AIN98259.1 - 0.0091 15.1 0.1 0.016 14.3 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 AIN98259.1 - 0.014 15.0 0.1 0.12 11.9 0.1 2.0 2 0 0 2 2 2 0 FAD dependent oxidoreductase Thi4 PF01946.17 AIN98259.1 - 0.035 13.3 0.5 0.035 13.3 0.5 2.0 2 0 0 2 2 2 0 Thi4 family Pyr_redox_3 PF13738.6 AIN98259.1 - 0.1 11.8 0.0 0.14 11.3 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pkinase PF00069.25 AIN98260.1 - 1.7e-63 214.5 0.0 3e-63 213.7 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 AIN98260.1 - 5.8e-44 150.3 0.0 1e-43 149.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 AIN98260.1 - 1.2e-05 24.8 0.0 1.2e-05 24.8 0.0 1.8 2 0 0 2 2 2 1 Kinase-like RIO1 PF01163.22 AIN98260.1 - 0.0021 17.7 1.0 0.0096 15.5 0.0 2.3 2 0 0 2 2 2 1 RIO1 family Pkinase_fungal PF17667.1 AIN98260.1 - 0.2 10.4 0.0 0.2 10.4 0.0 2.8 3 1 0 3 3 3 0 Fungal protein kinase MIP-T3_C PF17749.1 AIN98261.1 - 6.7e-51 172.3 6.9 6.7e-51 172.3 6.9 3.4 3 1 1 4 4 4 1 Microtubule-binding protein MIP-T3 C-terminal region MIP-T3 PF10243.9 AIN98261.1 - 4.5e-49 165.2 0.7 2e-48 163.0 0.2 2.2 2 0 0 2 2 2 1 Microtubule-binding protein MIP-T3 CH-like domain TFIIF_alpha PF05793.12 AIN98261.1 - 0.14 10.7 24.3 0.19 10.3 24.3 1.3 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) UPF0242 PF06785.11 AIN98261.1 - 1.3 9.0 17.2 0.043 13.9 2.3 2.5 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus RFXA_RFXANK_bdg PF15289.6 AIN98261.1 - 4.5 7.6 14.1 0.17 12.2 6.1 2.7 2 1 1 3 3 3 0 Regulatory factor X-associated C-terminal binding domain peroxidase PF00141.23 AIN98263.1 - 4.3e-11 42.9 0.0 7.5e-10 38.9 0.0 2.2 1 1 1 2 2 2 1 Peroxidase DUF4094 PF13334.6 AIN98263.1 - 0.0071 16.7 0.2 0.18 12.2 0.1 2.6 2 0 0 2 2 2 1 Domain of unknown function (DUF4094) ANAPC4_WD40 PF12894.7 AIN98264.1 - 0.084 13.2 0.2 0.73 10.2 0.0 2.6 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 AIN98264.1 - 0.29 12.1 5.8 2.7 9.0 0.1 4.4 5 0 0 5 5 5 0 WD domain, G-beta repeat Nodulin-like PF06813.13 AIN98265.1 - 1.9e-06 27.6 10.8 1.9e-06 27.6 10.8 2.9 3 0 0 3 3 3 1 Nodulin-like MFS_1 PF07690.16 AIN98265.1 - 0.00035 19.6 27.5 0.00035 19.6 27.5 3.0 2 1 0 2 2 2 1 Major Facilitator Superfamily F-box-like PF12937.7 AIN98266.1 - 1.9e-07 30.9 1.6 5.7e-07 29.3 1.6 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 AIN98266.1 - 4e-05 23.4 3.1 0.00016 21.4 3.1 2.1 1 0 0 1 1 1 1 F-box domain DUF5079 PF16882.5 AIN98266.1 - 1.8 8.4 13.6 0.1 12.5 1.9 2.4 1 1 0 2 2 2 0 Domain of unknown function (DUF5079) DUF4677 PF15726.5 AIN98267.1 - 0.0076 16.4 0.1 8.7 6.5 0.0 2.8 2 1 1 3 3 3 2 Domain of unknown function (DUF4677) TBD PF12845.7 AIN98267.1 - 0.024 14.5 0.0 0.09 12.7 0.0 2.0 1 0 0 1 1 1 0 TBD domain SfsA PF03749.13 AIN98267.1 - 0.033 14.1 0.5 0.64 9.9 0.1 2.5 1 1 1 2 2 2 0 Sugar fermentation stimulation protein RE domain Init_tRNA_PT PF04179.12 AIN98267.1 - 0.11 12.8 1.8 0.21 11.9 1.1 1.7 2 0 0 2 2 2 0 Rit1 DUSP-like domain DUF3782 PF12644.7 AIN98267.1 - 0.19 11.9 4.1 8.1 6.7 0.1 3.4 3 1 1 4 4 4 0 Protein of unknown function (DUF3782) SKA2 PF16740.5 AIN98267.1 - 0.72 9.7 9.0 0.17 11.7 0.7 3.1 3 1 0 3 3 3 0 Spindle and kinetochore-associated protein 2 BLOC1_2 PF10046.9 AIN98267.1 - 0.77 10.1 4.8 10 6.5 0.2 3.2 3 1 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 KELK PF15796.5 AIN98267.1 - 1 9.9 8.3 4.9 7.7 0.7 2.8 3 0 0 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase WXG100 PF06013.12 AIN98267.1 - 1.5 9.1 3.7 6.5 7.1 0.3 2.9 3 0 0 3 3 3 0 Proteins of 100 residues with WXG TMF_TATA_bd PF12325.8 AIN98267.1 - 2.6 8.3 7.5 0.46 10.7 1.0 2.5 3 0 0 3 3 3 0 TATA element modulatory factor 1 TATA binding zf-Sec23_Sec24 PF04810.15 AIN98268.1 - 0.046 13.8 4.0 0.057 13.5 0.1 2.3 2 0 0 2 2 2 0 Sec23/Sec24 zinc finger HpaB PF03241.13 AIN98268.1 - 0.12 11.4 0.0 0.17 10.9 0.0 1.2 1 0 0 1 1 1 0 4-hydroxyphenylacetate 3-hydroxylase C terminal DUF2407 PF10302.9 AIN98269.1 - 0.013 16.0 0.0 0.029 14.9 0.0 1.7 1 1 0 1 1 1 0 DUF2407 ubiquitin-like domain PPR_2 PF13041.6 AIN98270.1 - 1.1e-08 35.2 0.1 2.8e-08 33.8 0.0 1.8 2 0 0 2 2 2 1 PPR repeat family PPR_3 PF13812.6 AIN98270.1 - 1.6e-05 24.9 0.0 3e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 Pentatricopeptide repeat domain PPR PF01535.20 AIN98270.1 - 0.00012 22.1 0.7 0.00039 20.5 0.0 2.3 3 0 0 3 3 3 1 PPR repeat PPR_long PF17177.4 AIN98270.1 - 0.0052 16.2 0.1 0.0078 15.6 0.1 1.2 1 0 0 1 1 1 1 Pentacotripeptide-repeat region of PRORP PPR_1 PF12854.7 AIN98270.1 - 0.15 11.8 0.0 0.52 10.1 0.0 1.9 2 0 0 2 2 2 0 PPR repeat EF-hand_1 PF00036.32 AIN98271.1 - 7.2e-24 81.5 9.4 1e-06 27.8 0.2 4.5 5 0 0 5 5 5 4 EF hand EF-hand_7 PF13499.6 AIN98271.1 - 3.7e-22 78.5 3.7 7.2e-13 48.8 1.1 3.1 3 0 0 3 3 3 3 EF-hand domain pair EF-hand_6 PF13405.6 AIN98271.1 - 1.3e-19 68.4 8.3 6.7e-05 22.5 0.3 4.8 5 0 0 5 5 5 4 EF-hand domain EF-hand_5 PF13202.6 AIN98271.1 - 1.1e-16 59.4 13.1 5e-07 28.9 0.2 4.9 5 0 0 5 5 5 4 EF hand EF-hand_8 PF13833.6 AIN98271.1 - 6.4e-12 45.1 7.0 0.00024 20.9 1.1 4.1 3 2 1 4 4 4 4 EF-hand domain pair EF-hand_4 PF12763.7 AIN98271.1 - 1.6e-06 28.0 1.7 0.27 11.2 0.2 3.4 1 1 2 3 3 3 3 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 AIN98271.1 - 3.4e-06 27.3 0.0 0.014 15.7 0.0 2.4 2 1 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region Dockerin_1 PF00404.18 AIN98271.1 - 7.9e-06 26.0 0.7 0.00024 21.2 0.6 2.6 2 1 0 2 2 2 1 Dockerin type I domain DUF3349 PF11829.8 AIN98271.1 - 0.062 14.1 0.1 18 6.2 0.0 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF3349) DUF1425 PF07233.12 AIN98271.1 - 0.09 12.7 0.0 0.17 11.8 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1425) DUF5310 PF17237.2 AIN98272.1 - 0.0027 17.5 0.0 0.0077 16.1 0.0 1.8 1 0 0 1 1 1 1 Family of unknown function (DUF5310) TetR_C_31 PF17940.1 AIN98272.1 - 0.035 14.3 0.1 0.076 13.2 0.1 1.7 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain Pkinase PF00069.25 AIN98273.1 - 8.1e-41 140.1 0.0 1e-40 139.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 AIN98273.1 - 4.1e-10 39.4 0.0 7.2e-10 38.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 AIN98273.1 - 0.051 13.5 0.0 0.1 12.5 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family 5_3_exonuc_N PF02739.16 AIN98274.1 - 1.5e-26 93.2 0.1 2.3e-26 92.6 0.1 1.3 1 0 0 1 1 1 1 5'-3' exonuclease, N-terminal resolvase-like domain 5_3_exonuc PF01367.20 AIN98274.1 - 2.4e-19 69.7 0.0 4.4e-19 68.9 0.0 1.4 1 0 0 1 1 1 1 5'-3' exonuclease, C-terminal SAM fold EspB_PE PF18625.1 AIN98274.1 - 0.056 13.9 0.0 0.11 12.9 0.0 1.5 1 0 0 1 1 1 0 ESX-1 secreted protein B PE domain zf-MYND PF01753.18 AIN98276.1 - 0.0035 17.4 19.8 0.0073 16.4 19.8 1.6 1 0 0 1 1 1 1 MYND finger PUF PF00806.19 AIN98277.1 - 8.1e-49 160.7 6.5 1e-05 24.9 0.1 8.4 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat CPL PF08144.11 AIN98277.1 - 0.0018 18.6 0.6 8.5 6.7 0.0 3.7 2 1 1 3 3 3 3 CPL (NUC119) domain T_hemolysin PF12261.8 AIN98277.1 - 0.025 14.3 0.0 0.059 13.1 0.0 1.6 1 0 0 1 1 1 0 Thermostable hemolysin HrpB1_HrpK PF09613.10 AIN98277.1 - 0.027 14.1 0.2 1.3 8.7 0.1 3.0 3 0 0 3 3 3 0 Bacterial type III secretion protein (HrpB1_HrpK) MCU PF04678.13 AIN98278.1 - 1.1e-32 113.6 1.2 1.6e-32 113.0 1.2 1.3 1 0 0 1 1 1 1 Mitochondrial calcium uniporter DUF2339 PF10101.9 AIN98278.1 - 0.031 12.9 0.4 0.038 12.6 0.4 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2339) SYS1 PF09801.9 AIN98278.1 - 0.1 12.7 2.0 0.16 12.1 2.0 1.3 1 0 0 1 1 1 0 Integral membrane protein S linking to the trans Golgi network SLATT_1 PF18181.1 AIN98278.1 - 0.15 12.0 1.9 0.6 10.1 1.9 1.9 1 1 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain 1 Proteasome PF00227.26 AIN98279.1 - 8.1e-64 214.6 0.0 1.2e-63 214.1 0.0 1.2 1 1 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 AIN98279.1 - 4.1e-09 36.0 0.6 2.2e-08 33.6 0.1 2.2 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature YadA_head PF05658.14 AIN98279.1 - 0.32 11.5 6.8 0.95 9.9 1.2 2.3 2 0 0 2 2 2 0 Head domain of trimeric autotransporter adhesin DUF4874 PF16173.5 AIN98280.1 - 0.18 11.5 0.4 0.25 11.0 0.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4874) Ribosomal_L32e PF01655.18 AIN98281.1 - 1.2e-38 131.8 0.1 1.4e-38 131.6 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L32 PEHE PF15275.6 AIN98282.1 - 0.011 16.4 6.8 0.011 16.4 6.8 2.1 1 1 1 2 2 2 0 PEHE domain Wbp11 PF09429.10 AIN98282.1 - 0.19 12.1 17.3 0.061 13.7 10.1 2.3 2 0 0 2 2 2 0 WW domain binding protein 11 TipAS PF07739.13 AIN98282.1 - 5.7 7.5 9.3 1.5 9.4 5.2 2.0 2 1 0 2 2 2 0 TipAS antibiotic-recognition domain PAP_assoc PF03828.19 AIN98283.1 - 3.3e-05 24.0 0.3 0.00021 21.4 0.1 2.3 2 0 0 2 2 2 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.23 AIN98283.1 - 0.038 14.3 0.0 0.11 12.8 0.0 1.7 1 0 0 1 1 1 0 Nucleotidyltransferase domain SET PF00856.28 AIN98284.1 - 9e-06 26.2 0.6 0.00047 20.6 0.6 2.4 1 1 0 1 1 1 1 SET domain PHD PF00628.29 AIN98284.1 - 0.052 13.4 11.3 0.18 11.7 11.3 2.0 1 1 0 1 1 1 0 PHD-finger FYVE PF01363.21 AIN98284.1 - 0.73 10.0 9.7 2.5 8.3 9.7 1.9 1 0 0 1 1 1 0 FYVE zinc finger DKCLD PF08068.12 AIN98285.1 - 1.5e-31 108.3 0.1 2.4e-30 104.4 0.1 2.5 2 0 0 2 2 2 1 DKCLD (NUC011) domain TruB_N PF01509.18 AIN98285.1 - 4.9e-22 78.9 1.9 2.3e-15 57.2 0.4 3.3 1 1 1 2 2 2 2 TruB family pseudouridylate synthase (N terminal domain) TruB_C_2 PF16198.5 AIN98285.1 - 2.4e-20 72.5 0.3 4.3e-20 71.6 0.3 1.5 1 0 0 1 1 1 1 tRNA pseudouridylate synthase B C-terminal domain PUA PF01472.20 AIN98285.1 - 2.9e-20 72.0 1.0 5.5e-20 71.1 1.0 1.5 1 0 0 1 1 1 1 PUA domain UPF0113 PF03657.13 AIN98285.1 - 0.0021 18.3 0.0 0.0081 16.4 0.0 2.0 2 0 0 2 2 2 1 UPF0113 PUA domain ATP-synt PF00231.19 AIN98286.1 - 2.1e-50 172.0 2.2 2.4e-50 171.8 2.2 1.0 1 0 0 1 1 1 1 ATP synthase Ribosomal_S6e PF01092.19 AIN98287.1 - 3.7e-39 133.6 0.0 7.7e-39 132.5 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein S6e DnaB_bind PF10410.9 AIN98287.1 - 0.26 11.5 6.6 0.12 12.6 1.8 2.6 3 0 0 3 3 3 0 DnaB-helicase binding domain of primase RdRP_3 PF00998.23 AIN98287.1 - 0.4 9.3 6.2 0.48 9.1 6.2 1.1 1 0 0 1 1 1 0 Viral RNA dependent RNA polymerase ATP-synt_C PF00137.21 AIN98288.1 - 1.5e-26 92.5 34.3 3.2e-19 69.0 14.6 2.8 3 0 0 3 3 3 2 ATP synthase subunit C GerA PF03323.13 AIN98288.1 - 0.11 11.0 2.6 2.8 6.3 0.3 2.1 2 0 0 2 2 2 0 Bacillus/Clostridium GerA spore germination protein DUF4064 PF13273.6 AIN98288.1 - 3.9 7.8 15.4 2 8.7 4.3 2.9 1 1 1 2 2 2 0 Protein of unknown function (DUF4064) TctB PF07331.11 AIN98288.1 - 6.1 7.1 15.0 29 4.9 15.0 2.1 1 1 0 1 1 1 0 Tripartite tricarboxylate transporter TctB family Gaa1 PF04114.14 AIN98289.1 - 4.6e-10 39.1 1.1 4.6e-10 39.1 1.1 2.7 1 1 1 2 2 2 1 Gaa1-like, GPI transamidase component Ribosomal_L37ae PF01780.19 AIN98290.1 - 1.2e-36 124.6 4.5 1.4e-36 124.4 4.5 1.0 1 0 0 1 1 1 1 Ribosomal L37ae protein family C1_1 PF00130.22 AIN98290.1 - 0.0026 17.6 2.3 0.0038 17.1 2.3 1.2 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-RING_13 PF17977.1 AIN98290.1 - 0.059 13.5 1.1 0.087 13.0 1.1 1.3 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Zn_Tnp_IS1595 PF12760.7 AIN98290.1 - 0.077 13.0 2.3 0.13 12.3 2.3 1.4 1 0 0 1 1 1 0 Transposase zinc-ribbon domain NOB1_Zn_bind PF08772.11 AIN98290.1 - 0.3 11.3 4.5 2.9 8.1 4.0 2.3 1 1 0 1 1 1 0 Nin one binding (NOB1) Zn-ribbon like Proteasome PF00227.26 AIN98291.1 - 8e-59 198.3 0.0 1e-58 198.0 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 AIN98291.1 - 4.4e-13 48.6 0.0 1e-12 47.4 0.0 1.7 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Pex14_N PF04695.13 AIN98292.1 - 4.3e-23 82.7 0.5 4.3e-23 82.7 0.5 3.5 2 1 1 3 3 3 1 Peroxisomal membrane anchor protein (Pex14p) conserved region Rootletin PF15035.6 AIN98292.1 - 1.5e-06 28.4 0.3 2.3e-06 27.8 0.3 1.3 1 0 0 1 1 1 1 Ciliary rootlet component, centrosome cohesion HOOK PF05622.12 AIN98292.1 - 0.014 13.6 4.7 0.019 13.2 4.7 1.1 1 0 0 1 1 1 0 HOOK protein Spectrin PF00435.21 AIN98292.1 - 0.033 14.7 1.5 0.054 14.0 1.5 1.3 1 0 0 1 1 1 0 Spectrin repeat BLOC1_2 PF10046.9 AIN98292.1 - 0.038 14.3 3.3 0.068 13.5 3.3 1.3 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 TMCO5 PF14992.6 AIN98292.1 - 0.042 13.4 2.2 0.066 12.8 2.2 1.2 1 0 0 1 1 1 0 TMCO5 family Flagellin_C PF00700.21 AIN98292.1 - 0.048 14.0 1.9 0.1 13.0 1.9 1.6 1 0 0 1 1 1 0 Bacterial flagellin C-terminal helical region DUF2353 PF09789.9 AIN98292.1 - 0.048 13.0 2.9 0.068 12.5 2.9 1.1 1 0 0 1 1 1 0 Uncharacterized coiled-coil protein (DUF2353) DUF3450 PF11932.8 AIN98292.1 - 0.059 12.7 1.9 0.11 11.7 1.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) GAS PF13851.6 AIN98292.1 - 0.068 12.5 5.6 0.11 11.9 5.6 1.2 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding Atg14 PF10186.9 AIN98292.1 - 0.086 11.9 4.1 0.13 11.3 4.1 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Rab5-bind PF09311.11 AIN98292.1 - 0.19 11.1 5.3 0.31 10.4 5.3 1.2 1 0 0 1 1 1 0 Rabaptin-like protein CENP-H PF05837.12 AIN98292.1 - 0.25 11.8 7.6 0.45 10.9 7.6 1.4 1 0 0 1 1 1 0 Centromere protein H (CENP-H) DUF1192 PF06698.11 AIN98292.1 - 0.39 10.8 4.2 0.52 10.4 2.8 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF1192) Sec34 PF04136.15 AIN98292.1 - 0.46 10.4 2.6 0.72 9.7 2.6 1.2 1 0 0 1 1 1 0 Sec34-like family GIT_CC PF16559.5 AIN98292.1 - 0.48 10.3 2.5 0.79 9.6 1.1 2.1 1 1 1 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor DUF4407 PF14362.6 AIN98292.1 - 0.56 9.5 3.8 0.96 8.7 3.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Spc7 PF08317.11 AIN98292.1 - 0.63 8.9 6.4 0.92 8.3 6.4 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein FemAB PF02388.16 AIN98292.1 - 1.8 7.3 3.5 2.5 6.9 3.5 1.1 1 0 0 1 1 1 0 FemAB family DivIC PF04977.15 AIN98292.1 - 6.1 6.7 14.3 0.076 12.8 4.1 2.5 2 1 1 3 3 2 0 Septum formation initiator Rrp15p PF07890.12 AIN98293.1 - 1.5 9.2 10.8 5.5 7.3 10.8 1.9 1 0 0 1 1 1 0 Rrp15p BolA PF01722.18 AIN98294.1 - 1.3e-16 60.6 0.2 4.5e-16 58.9 0.2 1.7 1 1 0 1 1 1 1 BolA-like protein Sec66 PF09802.9 AIN98294.1 - 0.11 12.0 0.3 1.1 8.8 0.1 1.9 1 1 1 2 2 2 0 Preprotein translocase subunit Sec66 Hist_deacetyl PF00850.19 AIN98295.1 - 2.8e-75 253.7 0.1 3.4e-45 154.9 0.1 2.1 2 0 0 2 2 2 2 Histone deacetylase domain SR-25 PF10500.9 AIN98295.1 - 3.6 7.1 4.9 5.6 6.5 4.9 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein CLN3 PF02487.17 AIN98296.1 - 9.5e-42 143.4 23.1 2.2e-41 142.2 21.4 2.2 2 1 0 2 2 2 1 CLN3 protein Ribosomal_L5_C PF00673.21 AIN98298.1 - 8.3e-21 74.0 0.0 1.3e-20 73.3 0.0 1.3 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.19 AIN98298.1 - 9.4e-18 64.3 0.2 2.1e-16 60.0 0.0 2.3 2 0 0 2 2 2 1 Ribosomal protein L5 SET PF00856.28 AIN98299.1 - 0.0001 22.7 0.0 0.00013 22.5 0.0 1.3 1 0 0 1 1 1 1 SET domain SIP1 PF04938.12 AIN98299.1 - 0.11 12.2 0.0 0.17 11.5 0.0 1.2 1 0 0 1 1 1 0 Survival motor neuron (SMN) interacting protein 1 (SIP1) R3H PF01424.22 AIN98301.1 - 1.5e-11 44.1 0.1 3.1e-11 43.1 0.1 1.6 1 0 0 1 1 1 1 R3H domain zf-NF-X1 PF01422.17 AIN98301.1 - 6.2e-11 42.1 59.1 5.5e-06 26.3 14.2 15.9 16 1 1 17 17 17 9 NF-X1 type zinc finger HopA1 PF17914.1 AIN98301.1 - 0.084 12.6 0.1 8.1 6.2 0.0 2.6 2 0 0 2 2 2 0 HopA1 effector protein family Rad10 PF03834.14 AIN98302.1 - 0.00036 20.5 0.0 0.00055 19.9 0.0 1.2 1 0 0 1 1 1 1 Binding domain of DNA repair protein Ercc1 (rad10/Swi10) DnaJ_C PF01556.18 AIN98303.1 - 9.1e-29 100.5 0.0 1.2e-28 100.0 0.0 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.19 AIN98303.1 - 1.2e-11 44.8 8.9 2.8e-11 43.6 8.9 1.7 1 0 0 1 1 1 1 DnaJ central domain Anti-TRAP PF15777.5 AIN98303.1 - 0.0097 15.9 5.8 0.016 15.1 1.1 2.4 1 1 1 2 2 2 1 Tryptophan RNA-binding attenuator protein inhibitory protein DUF3556 PF12077.8 AIN98303.1 - 0.046 12.1 0.1 0.061 11.8 0.1 1.3 1 0 0 1 1 1 0 Transmembrane protein of unknown function (DUF3556) HypA PF01155.19 AIN98303.1 - 0.72 9.9 5.2 1 9.4 3.2 2.3 2 1 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Pox_MCEL PF03291.16 AIN98304.1 - 3.9e-44 151.1 0.0 5.8e-44 150.6 0.0 1.2 1 0 0 1 1 1 1 mRNA capping enzyme mRNA_cap_C PF03919.15 AIN98304.1 - 1.3e-07 32.2 0.0 3.5e-07 30.8 0.0 1.8 1 0 0 1 1 1 1 mRNA capping enzyme, C-terminal domain mRNA_cap_enzyme PF01331.19 AIN98304.1 - 2.7e-07 30.6 0.0 0.023 14.5 0.0 2.5 2 0 0 2 2 2 2 mRNA capping enzyme, catalytic domain Methyltransf_25 PF13649.6 AIN98304.1 - 0.0015 19.2 0.1 0.015 16.0 0.0 2.9 2 1 0 2 2 2 1 Methyltransferase domain GATase PF00117.28 AIN98306.1 - 1.1e-36 126.4 0.0 2e-36 125.6 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase class-I GMP_synt_C PF00958.22 AIN98306.1 - 3.5e-16 59.0 0.0 1.2e-08 34.9 0.0 2.9 2 1 0 2 2 2 2 GMP synthase C terminal domain Peptidase_C26 PF07722.13 AIN98306.1 - 2.1e-14 53.8 0.0 7.9e-14 51.9 0.0 2.0 1 1 0 1 1 1 1 Peptidase C26 NAD_synthase PF02540.17 AIN98306.1 - 2.5e-09 36.6 0.1 7.5e-05 22.0 0.0 2.3 2 0 0 2 2 2 2 NAD synthase QueC PF06508.13 AIN98306.1 - 5.4e-06 26.0 0.0 2e-05 24.2 0.0 1.9 1 1 0 1 1 1 1 Queuosine biosynthesis protein QueC ThiI PF02568.14 AIN98306.1 - 0.00016 21.3 0.2 0.00076 19.1 0.1 2.1 3 0 0 3 3 3 1 Thiamine biosynthesis protein (ThiI) PAPS_reduct PF01507.19 AIN98306.1 - 0.0028 17.7 0.0 0.0053 16.8 0.0 1.6 1 1 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family Arginosuc_synth PF00764.19 AIN98306.1 - 0.0041 16.5 0.0 0.0059 15.9 0.0 1.2 1 0 0 1 1 1 1 Arginosuccinate synthase ATP_bind_3 PF01171.20 AIN98306.1 - 0.0053 16.5 0.0 0.02 14.7 0.1 1.9 2 0 0 2 2 2 1 PP-loop family tRNA_Me_trans PF03054.16 AIN98306.1 - 0.022 13.5 0.0 0.05 12.4 0.1 1.6 2 0 0 2 2 2 0 tRNA methyl transferase GATase_3 PF07685.14 AIN98306.1 - 0.073 12.7 0.1 0.13 11.9 0.1 1.3 1 0 0 1 1 1 0 CobB/CobQ-like glutamine amidotransferase domain GP79 PF17463.2 AIN98306.1 - 0.11 12.5 0.3 0.33 11.0 0.3 1.8 1 0 0 1 1 1 0 Gene product 79 Asn_synthase PF00733.21 AIN98306.1 - 0.17 11.5 0.1 0.31 10.7 0.1 1.3 1 0 0 1 1 1 0 Asparagine synthase Tup_N PF08581.10 AIN98307.1 - 0.0038 17.5 10.4 0.051 13.9 0.1 3.1 2 1 1 3 3 3 2 Tup N-terminal Med20 PF08612.11 AIN98307.1 - 0.11 11.9 0.6 0.18 11.2 0.2 1.7 1 1 0 1 1 1 0 TATA-binding related factor (TRF) of subunit 20 of Mediator complex NRN1 PF15056.6 AIN98307.1 - 0.22 11.7 2.5 0.19 11.8 0.5 1.9 2 1 0 2 2 2 0 Neuritin protein family Cas_Cas5d PF09704.10 AIN98307.1 - 0.33 10.8 3.8 0.49 10.2 3.8 1.3 1 1 0 1 1 1 0 CRISPR-associated protein (Cas_Cas5) DUF1664 PF07889.12 AIN98307.1 - 1.8 8.6 14.2 0.44 10.6 3.6 3.1 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) Spc7 PF08317.11 AIN98307.1 - 1.8 7.4 29.6 1.2 8.0 18.2 2.1 1 1 1 2 2 2 0 Spc7 kinetochore protein DUF3584 PF12128.8 AIN98307.1 - 2.8 5.3 31.5 5.2 4.4 31.5 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3584) Golgin_A5 PF09787.9 AIN98307.1 - 3.4 7.0 28.8 2.7 7.4 15.1 2.2 1 1 1 2 2 2 0 Golgin subfamily A member 5 zf-CCCH PF00642.24 AIN98308.1 - 4.1e-05 23.4 16.9 0.0072 16.2 5.8 2.7 3 0 0 3 3 3 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Torus PF16131.5 AIN98308.1 - 0.0015 19.2 5.7 0.041 14.6 1.6 2.5 2 0 0 2 2 2 2 Torus domain ANAPC1 PF12859.7 AIN98308.1 - 0.017 15.7 0.2 0.071 13.7 0.2 2.1 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 1 BAG PF02179.16 AIN98309.1 - 4.7e-05 23.7 0.1 9.2e-05 22.8 0.1 1.4 1 0 0 1 1 1 1 BAG domain Dcc1 PF09724.9 AIN98310.1 - 1.5e-52 179.0 0.0 1.7e-52 178.8 0.0 1.0 1 0 0 1 1 1 1 Sister chromatid cohesion protein Dcc1 zf-CCCH_4 PF18044.1 AIN98311.1 - 2.6e-08 33.4 12.8 0.00021 21.0 3.6 3.0 2 0 0 2 2 2 2 CCCH-type zinc finger zf-CCCH PF00642.24 AIN98311.1 - 1.2e-06 28.3 19.6 1.6e-05 24.7 2.0 3.9 4 0 0 4 4 4 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 AIN98311.1 - 8e-06 25.7 17.4 0.004 17.2 3.2 3.2 3 0 0 3 3 3 2 Zinc finger domain Torus PF16131.5 AIN98311.1 - 2.6e-05 24.9 1.2 0.11 13.2 0.6 2.6 2 0 0 2 2 2 2 Torus domain ApoO PF09769.9 AIN98313.1 - 0.0024 17.8 3.3 0.005 16.8 1.9 2.2 1 1 1 2 2 2 2 Apolipoprotein O Apolipoprotein PF01442.18 AIN98313.1 - 0.0038 17.1 7.2 0.0093 15.9 7.2 1.6 1 1 0 1 1 1 1 Apolipoprotein A1/A4/E domain ApoLp-III PF07464.11 AIN98313.1 - 0.0043 17.1 5.4 0.0043 17.1 5.4 1.9 2 0 0 2 2 2 1 Apolipophorin-III precursor (apoLp-III) DUF883 PF05957.13 AIN98313.1 - 0.0056 17.2 10.9 0.27 11.8 3.1 2.5 1 1 2 3 3 3 3 Bacterial protein of unknown function (DUF883) ATG_C PF09333.11 AIN98313.1 - 0.0067 16.8 4.5 0.11 12.9 2.7 2.6 1 1 1 2 2 2 1 Autophagy-related protein C terminal domain Prominin PF05478.11 AIN98313.1 - 0.014 13.4 1.9 0.018 13.0 1.9 1.1 1 0 0 1 1 1 0 Prominin LXG PF04740.12 AIN98313.1 - 0.014 15.1 2.5 0.051 13.3 2.5 2.0 1 1 0 1 1 1 0 LXG domain of WXG superfamily ATP-synt_B PF00430.18 AIN98313.1 - 0.016 15.3 8.7 0.016 15.3 8.7 1.8 2 0 0 2 2 1 0 ATP synthase B/B' CF(0) KfrA_N PF11740.8 AIN98313.1 - 0.016 15.8 5.6 0.038 14.7 5.6 1.7 1 0 0 1 1 1 0 Plasmid replication region DNA-binding N-term Alba PF01918.21 AIN98313.1 - 0.021 14.6 0.4 0.56 10.1 0.1 2.9 2 1 0 2 2 2 0 Alba DUF5082 PF16888.5 AIN98313.1 - 0.028 14.7 1.9 0.056 13.7 1.9 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5082) DUF3987 PF13148.6 AIN98313.1 - 0.042 12.9 1.5 0.056 12.5 1.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) YtxH PF12732.7 AIN98313.1 - 0.094 13.3 9.8 12 6.5 9.8 2.4 1 1 0 1 1 1 0 YtxH-like protein DUF2564 PF10819.8 AIN98313.1 - 0.11 12.9 10.6 0.32 11.4 2.7 3.0 2 1 2 4 4 3 0 Protein of unknown function (DUF2564) SCAB_CC PF16712.5 AIN98313.1 - 0.13 12.1 9.4 2.1 8.2 1.3 2.4 1 1 1 2 2 2 0 Coiled-coil regions of plant-specific actin-binding protein DUF357 PF04010.13 AIN98313.1 - 0.14 12.3 1.4 0.78 9.9 0.2 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF357) RRF PF01765.19 AIN98313.1 - 0.26 11.2 8.9 0.35 10.8 1.4 2.2 1 1 1 2 2 2 0 Ribosome recycling factor Activator-TraM PF11657.8 AIN98313.1 - 0.36 10.7 5.8 0.054 13.3 1.7 1.8 2 1 1 3 3 2 0 Transcriptional activator TraM DivIVA PF05103.13 AIN98313.1 - 0.41 10.7 9.2 1.8 8.6 9.2 2.0 1 1 0 1 1 1 0 DivIVA protein Uso1_p115_C PF04871.13 AIN98313.1 - 0.52 10.7 8.9 1.5 9.2 8.8 1.9 1 1 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region Phasin PF05597.11 AIN98313.1 - 0.8 9.7 9.2 2.6 8.1 1.7 2.3 1 1 1 2 2 2 0 Poly(hydroxyalcanoate) granule associated protein (phasin) Alanine_zipper PF11839.8 AIN98313.1 - 0.87 10.0 17.4 25 5.3 2.1 2.6 1 1 1 2 2 2 0 Alanine-zipper, major outer membrane lipoprotein Med25_SD1 PF11235.8 AIN98313.1 - 3.1 8.1 9.0 1.5 9.1 4.1 2.1 2 0 0 2 2 2 0 Mediator complex subunit 25 synapsin 1 ISG65-75 PF11727.8 AIN98313.1 - 3.3 6.9 11.7 6.3 6.0 11.7 1.5 1 1 0 1 1 1 0 Invariant surface glycoprotein DNA_pol_phi PF04931.13 AIN98315.1 - 0.0034 15.6 0.0 0.0034 15.6 0.0 3.1 3 1 0 3 3 3 2 DNA polymerase phi Glypican PF01153.19 AIN98315.1 - 6.4 5.5 7.2 14 4.4 7.2 1.5 1 0 0 1 1 1 0 Glypican DUF1736 PF08409.11 AIN98316.1 - 6.6e-18 64.5 0.2 1.8e-17 63.1 0.2 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1736) TPR_17 PF13431.6 AIN98316.1 - 0.0041 17.4 0.1 1.3 9.6 0.0 3.1 2 0 0 2 2 2 1 Tetratricopeptide repeat DUF3040 PF11239.8 AIN98316.1 - 0.51 10.6 6.3 7.6 6.9 1.2 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF3040) IPTL-CTERM PF18203.1 AIN98316.1 - 0.77 9.7 3.9 1.4 8.9 0.5 3.2 1 1 1 2 2 2 0 IPTL-CTERM motif Aa_trans PF01490.18 AIN98317.1 - 2.7e-61 207.5 37.1 3.5e-61 207.1 37.1 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 AIN98317.1 - 6e-05 22.3 12.8 6e-05 22.3 12.8 2.2 2 0 0 2 2 2 1 Tryptophan/tyrosine permease family TRAP_alpha PF03896.16 AIN98319.1 - 2.1e-15 56.7 0.1 2.4e-15 56.5 0.1 1.1 1 0 0 1 1 1 1 Translocon-associated protein (TRAP), alpha subunit Wzt_C PF14524.6 AIN98319.1 - 0.0051 16.9 0.0 0.0098 15.9 0.0 1.4 1 1 0 1 1 1 1 Wzt C-terminal domain zf-Tim10_DDP PF02953.15 AIN98320.1 - 5e-10 38.9 2.9 5.2e-10 38.8 2.9 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger Mito_carr PF00153.27 AIN98323.1 - 2.8e-10 40.0 0.5 3.4e-08 33.3 0.1 3.3 3 0 0 3 3 3 1 Mitochondrial carrier protein DUF2618 PF10940.8 AIN98324.1 - 0.27 11.0 0.8 0.62 9.9 0.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2618) Carn_acyltransf PF00755.20 AIN98325.1 - 7.9e-89 298.9 0.0 1e-88 298.5 0.0 1.1 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase SEP PF08059.13 AIN98326.1 - 3.2e-15 56.5 0.0 8.8e-15 55.0 0.0 1.8 1 0 0 1 1 1 1 SEP domain CUE PF02845.16 AIN98326.1 - 0.0045 16.7 0.0 0.011 15.5 0.0 1.6 1 0 0 1 1 1 1 CUE domain UBA_4 PF14555.6 AIN98326.1 - 0.027 14.3 0.2 0.061 13.2 0.2 1.5 1 0 0 1 1 1 0 UBA-like domain CopC PF04234.12 AIN98327.1 - 0.05 14.7 0.2 1.5 9.9 0.0 2.8 2 0 0 2 2 2 0 CopC domain DUF4061 PF13270.6 AIN98328.1 - 0.011 16.0 2.6 0.015 15.6 1.4 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4061) Baculo_PEP_C PF04513.12 AIN98328.1 - 0.045 13.8 0.7 0.078 13.0 0.7 1.4 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus ALMT PF11744.8 AIN98328.1 - 0.047 12.5 1.3 0.057 12.2 1.3 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter SLS PF14611.6 AIN98328.1 - 0.05 13.4 0.4 0.062 13.1 0.4 1.1 1 0 0 1 1 1 0 Mitochondrial inner-membrane-bound regulator Prominin PF05478.11 AIN98328.1 - 0.18 9.7 1.4 0.23 9.4 1.4 1.0 1 0 0 1 1 1 0 Prominin Macoilin PF09726.9 AIN98328.1 - 0.41 9.2 6.4 0.52 8.8 6.4 1.0 1 0 0 1 1 1 0 Macoilin family Peptidase_S46 PF10459.9 AIN98328.1 - 1.1 7.9 7.0 1.3 7.5 7.0 1.0 1 0 0 1 1 1 0 Peptidase S46 CHD5 PF04420.14 AIN98328.1 - 1.3 8.9 3.8 1.9 8.3 3.8 1.3 1 0 0 1 1 1 0 CHD5-like protein OPA3 PF07047.12 AIN98329.1 - 0.033 14.0 0.6 0.066 13.0 0.6 1.5 1 0 0 1 1 1 0 Optic atrophy 3 protein (OPA3) DUF4695 PF15766.5 AIN98329.1 - 1.9 8.7 6.1 3.2 8.0 0.6 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4695) betaPIX_CC PF16523.5 AIN98329.1 - 2.9 7.8 5.6 0.73 9.7 0.5 2.1 2 0 0 2 2 2 0 betaPIX coiled coil ZapA PF05164.13 AIN98329.1 - 3.2 8.3 8.9 14 6.2 8.9 2.1 1 1 0 1 1 1 0 Cell division protein ZapA DNA_primase_S PF01896.19 AIN98332.1 - 4.8e-41 140.7 0.1 7.4e-41 140.1 0.1 1.3 1 0 0 1 1 1 1 DNA primase small subunit cNMP_binding PF00027.29 AIN98333.1 - 2e-05 24.6 0.0 1 9.5 0.0 3.9 4 0 0 4 4 4 2 Cyclic nucleotide-binding domain Ephrin_rec_like PF07699.13 AIN98334.1 - 2.7e-05 23.8 18.1 0.00012 21.8 3.2 9.3 6 3 3 9 9 9 5 Putative ephrin-receptor like NCD3G PF07562.14 AIN98334.1 - 8.5 6.4 55.4 0.036 14.0 5.4 7.4 6 2 3 9 9 9 0 Nine Cysteines Domain of family 3 GPCR Ribosomal_S19 PF00203.21 AIN98335.1 - 4.2e-28 97.0 0.3 6.1e-28 96.5 0.3 1.2 1 0 0 1 1 1 1 Ribosomal protein S19 PmbA_TldD PF01523.16 AIN98335.1 - 0.07 13.0 0.0 0.078 12.8 0.0 1.1 1 0 0 1 1 1 0 Putative modulator of DNA gyrase Acetyltransf_1 PF00583.25 AIN98337.1 - 2.5e-09 37.4 0.0 3.9e-09 36.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 AIN98337.1 - 7.1e-06 26.4 0.0 1.2e-05 25.6 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 AIN98337.1 - 0.00023 21.1 0.0 0.00042 20.2 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.7 AIN98337.1 - 0.00025 21.0 0.0 0.00055 19.9 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 AIN98337.1 - 0.016 14.9 0.0 0.031 14.0 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Ribosomal_S19 PF00203.21 AIN98338.1 - 4.2e-28 97.0 0.3 6.1e-28 96.5 0.3 1.2 1 0 0 1 1 1 1 Ribosomal protein S19 PmbA_TldD PF01523.16 AIN98338.1 - 0.07 13.0 0.0 0.078 12.8 0.0 1.1 1 0 0 1 1 1 0 Putative modulator of DNA gyrase tRNA_bind PF01588.20 AIN98339.1 - 3.4e-25 88.0 0.0 6.4e-25 87.1 0.0 1.5 1 0 0 1 1 1 1 Putative tRNA binding domain Dynamin_N PF00350.23 AIN98340.1 - 3.1e-12 46.9 0.0 1.9e-11 44.3 0.0 2.0 1 1 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.23 AIN98340.1 - 7.3e-09 35.7 0.0 3.8e-08 33.4 0.0 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 AIN98340.1 - 0.00054 19.9 0.4 0.058 13.3 0.4 3.0 2 1 0 2 2 2 1 RsgA GTPase FeoB_N PF02421.18 AIN98340.1 - 0.0037 16.8 0.0 0.31 10.5 0.0 2.7 2 1 0 2 2 2 1 Ferrous iron transport protein B Roc PF08477.13 AIN98340.1 - 0.0076 16.5 0.0 2 8.7 0.0 2.4 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase GTP_EFTU PF00009.27 AIN98340.1 - 0.014 14.9 0.1 0.47 10.0 0.0 2.7 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain ABC_tran PF00005.27 AIN98340.1 - 0.049 14.1 0.0 0.1 13.1 0.0 1.5 1 0 0 1 1 1 0 ABC transporter AAA_29 PF13555.6 AIN98340.1 - 0.16 11.7 0.0 0.33 10.7 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain G-alpha PF00503.20 AIN98340.1 - 0.22 10.6 0.2 6.5 5.8 0.0 2.3 2 0 0 2 2 2 0 G-protein alpha subunit Pkinase PF00069.25 AIN98341.1 - 3e-43 148.1 0.0 6e-31 107.8 0.0 4.0 4 0 0 4 4 4 3 Protein kinase domain Pkinase_Tyr PF07714.17 AIN98341.1 - 1.3e-20 73.8 0.0 2e-17 63.4 0.0 2.9 3 1 0 3 3 3 2 Protein tyrosine kinase Kdo PF06293.14 AIN98341.1 - 0.00012 21.5 0.1 0.0002 20.8 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 AIN98341.1 - 0.00029 20.8 0.4 0.00029 20.8 0.4 2.0 2 0 0 2 2 2 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 AIN98341.1 - 0.0094 14.9 0.0 0.014 14.3 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Choline_kinase PF01633.20 AIN98341.1 - 0.042 13.4 0.0 0.07 12.7 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase Med26 PF08711.11 AIN98342.1 - 0.00029 20.8 8.4 0.019 15.0 0.0 3.5 3 0 0 3 3 3 2 TFIIS helical bundle-like domain DASH_Spc19 PF08287.11 AIN98342.1 - 0.57 10.1 13.4 0.84 9.5 0.1 2.4 2 0 0 2 2 2 0 Spc19 COX5B PF01215.19 AIN98343.1 - 0.0023 17.6 0.0 0.0042 16.8 0.0 1.3 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Vb CxC6 PF18721.1 AIN98343.1 - 0.063 13.6 0.0 0.13 12.5 0.0 1.4 1 0 0 1 1 1 0 CxC6 like cysteine cluster associated with KDZ transposases RabGAP-TBC PF00566.18 AIN98344.1 - 9e-31 107.2 0.0 1.2e-30 106.7 0.0 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain FHA PF00498.26 AIN98345.1 - 1.1e-14 54.5 0.0 1.7e-14 53.9 0.0 1.3 1 0 0 1 1 1 1 FHA domain Rotamase PF00639.21 AIN98345.1 - 2.9e-12 47.4 0.0 7.2e-12 46.1 0.0 1.7 1 1 0 1 1 1 1 PPIC-type PPIASE domain Yop-YscD_cpl PF16697.5 AIN98345.1 - 6.1e-08 32.9 0.0 1.3e-07 31.8 0.0 1.5 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain Rotamase_3 PF13616.6 AIN98345.1 - 4.5e-07 30.4 0.0 8.1e-07 29.6 0.0 1.3 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_2 PF13145.6 AIN98345.1 - 0.0077 17.1 0.0 0.048 14.5 0.0 2.2 2 0 0 2 2 2 1 PPIC-type PPIASE domain DUF3439 PF11921.8 AIN98345.1 - 0.017 15.1 1.4 0.032 14.2 1.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) PPR PF01535.20 AIN98346.1 - 0.055 13.7 0.0 42 4.7 0.0 4.0 3 0 0 3 3 3 0 PPR repeat TPR_4 PF07721.14 AIN98346.1 - 0.93 10.3 6.9 0.86 10.4 4.1 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_16 PF13432.6 AIN98346.1 - 1.4 9.7 15.2 0.39 11.4 6.7 4.1 3 2 0 3 3 3 0 Tetratricopeptide repeat Kinesin PF00225.23 AIN98347.1 - 2e-83 280.1 6.3 1e-46 159.4 0.1 3.1 3 0 0 3 3 3 2 Kinesin motor domain Microtub_bd PF16796.5 AIN98347.1 - 6.1e-21 74.9 0.0 2.6e-20 72.9 0.0 2.2 2 0 0 2 2 2 1 Microtubule binding AAA_33 PF13671.6 AIN98347.1 - 0.0035 17.5 0.0 0.024 14.8 0.0 2.5 1 0 0 1 1 1 1 AAA domain TPR_MLP1_2 PF07926.12 AIN98347.1 - 0.0037 17.3 17.2 0.0037 17.3 17.2 4.9 3 1 2 5 5 5 1 TPR/MLP1/MLP2-like protein DivIC PF04977.15 AIN98347.1 - 0.027 14.2 0.3 0.027 14.2 0.3 5.9 3 1 1 5 5 5 0 Septum formation initiator HTH_27 PF13463.6 AIN98347.1 - 0.24 11.9 7.4 13 6.4 0.1 4.7 5 0 0 5 5 5 0 Winged helix DNA-binding domain GCIP PF13324.6 AIN98347.1 - 0.45 10.1 12.7 0.067 12.8 0.6 2.7 2 0 0 2 2 2 0 Grap2 and cyclin-D-interacting Pox_A_type_inc PF04508.12 AIN98347.1 - 3.6 7.6 7.0 59 3.7 0.9 4.3 4 0 0 4 4 4 0 Viral A-type inclusion protein repeat Fungal_TACC PF12709.7 AIN98347.1 - 5.4 7.5 20.9 8.9 6.8 0.9 4.6 2 1 2 4 4 4 0 Fungal Transforming acidic coiled-coil (TACC) proteins AAA PF00004.29 AIN98348.1 - 1.9e-43 148.0 0.0 4e-43 147.0 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 AIN98348.1 - 2.4e-10 40.0 0.0 4.9e-10 39.1 0.0 1.5 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 AIN98348.1 - 4.4e-06 26.7 0.1 4.3e-05 23.5 0.0 2.3 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 AIN98348.1 - 1.3e-05 25.5 0.1 0.0054 17.0 0.0 2.4 1 1 1 2 2 2 1 AAA domain AAA_16 PF13191.6 AIN98348.1 - 1.9e-05 25.1 0.2 0.00082 19.8 0.0 2.2 1 1 0 2 2 2 1 AAA ATPase domain AAA_2 PF07724.14 AIN98348.1 - 2e-05 24.8 0.0 4.6e-05 23.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) DUF815 PF05673.13 AIN98348.1 - 0.00017 20.8 0.0 0.00031 20.0 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) RuvB_N PF05496.12 AIN98348.1 - 0.00025 20.8 0.0 0.00066 19.4 0.0 1.7 2 0 0 2 2 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_28 PF13521.6 AIN98348.1 - 0.0021 18.3 0.0 0.0037 17.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain ATPase_2 PF01637.18 AIN98348.1 - 0.0053 16.7 0.0 0.35 10.8 0.0 2.4 1 1 1 2 2 2 1 ATPase domain predominantly from Archaea AAA_7 PF12775.7 AIN98348.1 - 0.0054 16.3 0.0 0.013 15.0 0.0 1.5 1 1 0 1 1 1 1 P-loop containing dynein motor region AAA_33 PF13671.6 AIN98348.1 - 0.0063 16.7 0.0 0.012 15.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.6 AIN98348.1 - 0.008 16.2 0.0 0.02 15.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 AIN98348.1 - 0.0084 16.5 0.0 0.02 15.3 0.0 1.6 1 0 0 1 1 1 1 RNA helicase Mg_chelatase PF01078.21 AIN98348.1 - 0.0087 15.5 0.0 0.023 14.1 0.0 1.6 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 AIN98348.1 - 0.011 15.5 0.0 0.018 14.8 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein TIP49 PF06068.13 AIN98348.1 - 0.011 15.0 0.0 0.02 14.1 0.0 1.3 1 0 0 1 1 1 0 TIP49 P-loop domain AAA_18 PF13238.6 AIN98348.1 - 0.012 16.2 0.1 0.036 14.6 0.0 1.9 2 0 0 2 2 1 0 AAA domain AAA_3 PF07726.11 AIN98348.1 - 0.013 15.4 0.0 0.032 14.1 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.6 AIN98348.1 - 0.015 15.0 0.1 0.057 13.1 0.1 1.9 2 0 0 2 2 2 0 AAA domain Sigma54_activat PF00158.26 AIN98348.1 - 0.055 13.2 0.0 0.15 11.8 0.0 1.7 2 0 0 2 2 1 0 Sigma-54 interaction domain NTPase_1 PF03266.15 AIN98348.1 - 0.055 13.4 0.0 0.12 12.3 0.0 1.6 1 0 0 1 1 1 0 NTPase Parvo_NS1 PF01057.17 AIN98348.1 - 0.081 12.0 0.0 0.15 11.2 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Zeta_toxin PF06414.12 AIN98348.1 - 0.1 11.9 0.0 0.25 10.6 0.0 1.7 1 0 0 1 1 1 0 Zeta toxin PhoH PF02562.16 AIN98348.1 - 0.13 11.7 0.2 0.29 10.6 0.1 1.6 1 1 0 1 1 1 0 PhoH-like protein AAA_19 PF13245.6 AIN98348.1 - 0.14 12.5 0.0 0.46 10.8 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.6 AIN98348.1 - 0.15 11.7 0.0 0.4 10.2 0.0 1.7 2 0 0 2 2 2 0 AAA domain TsaE PF02367.17 AIN98348.1 - 0.15 12.1 0.0 0.26 11.3 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_30 PF13604.6 AIN98348.1 - 0.15 11.7 0.0 0.27 10.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain Rer1 PF03248.13 AIN98349.1 - 2.1e-53 180.6 4.9 2.5e-53 180.3 4.9 1.0 1 0 0 1 1 1 1 Rer1 family DmsC PF04976.12 AIN98349.1 - 0.0027 17.2 0.7 0.0043 16.6 0.7 1.3 1 1 0 1 1 1 1 DMSO reductase anchor subunit (DmsC) DUF2244 PF10003.9 AIN98349.1 - 3.8 7.2 9.8 7.7 6.2 0.2 2.1 2 0 0 2 2 2 0 Integral membrane protein (DUF2244) TrmO PF01980.16 AIN98350.1 - 7.2e-30 103.7 0.0 1.7e-24 86.3 0.0 2.4 2 0 0 2 2 2 2 tRNA-methyltransferase O PWWP PF00855.17 AIN98350.1 - 0.00012 22.4 0.8 0.00053 20.3 0.2 2.3 2 1 0 2 2 2 1 PWWP domain BCL9 PF11502.8 AIN98350.1 - 0.34 10.8 3.6 0.78 9.6 3.6 1.6 1 0 0 1 1 1 0 B-cell lymphoma 9 protein Acetyltransf_3 PF13302.7 AIN98351.1 - 8.6e-10 39.4 0.1 1.3e-07 32.4 0.0 3.1 2 1 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 AIN98351.1 - 6.8e-08 32.8 0.0 1.2e-05 25.6 0.0 2.6 2 0 0 2 2 2 2 Acetyltransferase (GNAT) family Acetyltransf_8 PF13523.6 AIN98351.1 - 0.0057 16.3 0.5 0.017 14.8 0.1 2.0 3 0 0 3 3 3 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 AIN98351.1 - 0.2 11.6 0.0 0.45 10.5 0.0 1.5 1 0 0 1 1 1 0 FR47-like protein UQ_con PF00179.26 AIN98352.1 - 7.2e-42 142.4 0.0 1e-41 141.8 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 AIN98352.1 - 0.0004 20.1 0.0 0.00056 19.6 0.0 1.4 1 0 0 1 1 1 1 Prokaryotic E2 family B AAA PF00004.29 AIN98353.1 - 6.6e-38 130.1 0.4 1.7e-37 128.8 0.0 1.9 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 AIN98353.1 - 3.7e-17 62.0 0.6 9.5e-17 60.7 0.6 1.7 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_lid_3 PF17862.1 AIN98353.1 - 2.7e-12 46.3 0.2 7e-12 45.0 0.2 1.8 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 AIN98353.1 - 3e-05 24.0 0.1 0.00031 20.8 0.1 2.7 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 AIN98353.1 - 3.3e-05 24.3 3.2 0.0032 17.9 0.0 3.0 2 2 1 3 3 3 1 AAA ATPase domain AAA_2 PF07724.14 AIN98353.1 - 0.00039 20.6 0.1 0.004 17.3 0.0 2.5 2 1 0 2 2 2 1 AAA domain (Cdc48 subfamily) RuvB_N PF05496.12 AIN98353.1 - 0.00043 20.0 0.0 0.00098 18.9 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 AIN98353.1 - 0.0013 19.0 3.6 0.25 11.6 0.1 3.1 2 1 0 3 3 3 1 AAA domain DUF815 PF05673.13 AIN98353.1 - 0.0015 17.7 0.3 0.0041 16.3 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_33 PF13671.6 AIN98353.1 - 0.0064 16.7 1.6 0.036 14.2 0.0 2.6 2 1 0 2 2 2 1 AAA domain Mg_chelatase PF01078.21 AIN98353.1 - 0.0074 15.7 0.0 0.018 14.4 0.0 1.6 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_24 PF13479.6 AIN98353.1 - 0.021 14.5 0.0 0.065 13.0 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.6 AIN98353.1 - 0.051 13.2 1.2 0.21 11.1 0.0 2.4 3 0 0 3 3 3 0 AAA domain ATPase PF06745.13 AIN98353.1 - 0.052 12.9 0.1 0.14 11.4 0.0 1.8 2 0 0 2 2 2 0 KaiC PhoH PF02562.16 AIN98353.1 - 0.058 12.8 0.1 0.36 10.3 0.0 2.1 2 0 0 2 2 2 0 PhoH-like protein IstB_IS21 PF01695.17 AIN98353.1 - 0.065 13.0 0.5 0.15 11.7 0.0 1.8 2 0 0 2 2 2 0 IstB-like ATP binding protein Sigma54_activat PF00158.26 AIN98353.1 - 0.075 12.7 0.0 0.39 10.4 0.0 2.1 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_18 PF13238.6 AIN98353.1 - 0.083 13.4 0.9 0.33 11.5 0.0 2.4 2 1 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 AIN98353.1 - 0.084 12.1 1.4 0.11 11.7 0.0 1.9 2 0 0 2 2 2 0 Zeta toxin TsaE PF02367.17 AIN98353.1 - 0.12 12.4 0.0 0.29 11.1 0.0 1.6 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE NACHT PF05729.12 AIN98353.1 - 0.15 11.9 0.2 0.63 9.9 0.1 2.1 2 0 0 2 2 2 0 NACHT domain Torus PF16131.5 AIN98356.1 - 0.035 14.8 1.5 0.093 13.4 1.5 1.7 1 0 0 1 1 1 0 Torus domain Prefoldin PF02996.17 AIN98357.1 - 3.5e-19 68.9 3.8 4.7e-19 68.5 2.6 1.6 1 1 1 2 2 2 1 Prefoldin subunit TENA_THI-4 PF03070.16 AIN98357.1 - 0.00049 20.0 0.8 0.00064 19.6 0.8 1.1 1 0 0 1 1 1 1 TENA/THI-4/PQQC family Prefoldin_2 PF01920.20 AIN98357.1 - 0.004 17.1 2.1 0.045 13.7 1.8 2.1 2 0 0 2 2 2 1 Prefoldin subunit Sec20 PF03908.13 AIN98357.1 - 0.058 13.3 2.3 13 5.8 1.4 2.5 2 1 1 3 3 3 0 Sec20 THF_DHG_CYH_C PF02882.19 AIN98357.1 - 0.072 12.4 0.1 0.11 11.8 0.1 1.4 1 1 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain DUF1454 PF07305.12 AIN98358.1 - 0.058 12.8 0.0 0.082 12.3 0.0 1.2 1 1 0 1 1 1 0 Protein of unknown function (DUF1454) Torus PF16131.5 AIN98359.1 - 3.8e-05 24.4 0.3 0.32 11.7 0.1 2.5 2 0 0 2 2 2 2 Torus domain zf_CCCH_4 PF18345.1 AIN98359.1 - 4.4e-05 23.4 12.1 0.00083 19.3 1.8 2.6 2 0 0 2 2 2 2 Zinc finger domain zf-CCCH PF00642.24 AIN98359.1 - 0.033 14.1 0.6 0.033 14.1 0.6 2.5 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 AIN98359.1 - 6.8 6.6 8.5 1.7 8.5 1.4 2.5 2 0 0 2 2 2 0 CCCH-type zinc finger zf_CCCH_4 PF18345.1 AIN98360.1 - 0.003 17.5 10.6 0.24 11.5 1.4 2.5 2 0 0 2 2 2 2 Zinc finger domain zf-CCCH PF00642.24 AIN98360.1 - 0.029 14.3 0.8 0.029 14.3 0.8 3.4 3 0 0 3 3 3 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 AIN98360.1 - 0.15 11.9 10.4 0.83 9.5 2.0 2.4 2 0 0 2 2 2 0 CCCH-type zinc finger NAD_binding_1 PF00175.21 AIN98362.1 - 1.1e-26 93.7 0.0 1.6e-26 93.1 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 AIN98362.1 - 1.4e-24 86.3 0.0 2.4e-24 85.6 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.12 AIN98362.1 - 2.5e-05 24.5 0.2 0.00035 20.7 0.0 2.2 1 1 0 2 2 2 1 Ferric reductase NAD binding domain NAD_binding_1 PF00175.21 AIN98363.1 - 4.7e-26 91.6 0.0 6.5e-26 91.1 0.0 1.2 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 AIN98363.1 - 1.4e-20 73.5 0.0 2.5e-20 72.7 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.12 AIN98363.1 - 8.3e-07 29.3 0.0 5.2e-06 26.7 0.0 1.9 2 0 0 2 2 2 1 Ferric reductase NAD binding domain SUI1 PF01253.22 AIN98364.1 - 2.5e-17 63.2 0.0 1.7e-16 60.5 0.0 2.5 3 0 0 3 3 3 1 Translation initiation factor SUI1 Pre-PUA PF17832.1 AIN98364.1 - 2e-07 31.6 1.1 8.7e-07 29.5 0.4 2.5 2 0 0 2 2 2 1 Pre-PUA-like domain PUA PF01472.20 AIN98364.1 - 0.0076 16.2 0.3 0.029 14.3 0.0 2.1 2 0 0 2 2 2 1 PUA domain zinc_ribbon_10 PF10058.9 AIN98365.1 - 9.9e-05 22.0 9.7 0.00093 18.9 0.1 3.4 3 1 0 3 3 3 2 Predicted integral membrane zinc-ribbon metal-binding protein Mu-like_Com PF10122.9 AIN98365.1 - 0.017 14.6 11.5 0.17 11.4 0.1 3.2 3 1 1 4 4 4 0 Mu-like prophage protein Com Cytochrom_CIII PF02085.16 AIN98365.1 - 0.077 13.3 8.6 0.12 12.8 7.6 1.8 1 1 0 1 1 1 0 Class III cytochrome C family zf-Sec23_Sec24 PF04810.15 AIN98365.1 - 0.17 12.0 13.1 8 6.6 0.2 4.2 4 0 0 4 4 4 0 Sec23/Sec24 zinc finger Cytochrom_c3_2 PF14537.6 AIN98365.1 - 0.21 12.1 11.8 0.23 12.0 7.9 2.5 1 1 1 2 2 2 0 Cytochrome c3 VATC PF18716.1 AIN98365.1 - 0.3 11.0 0.2 0.3 11.0 0.2 3.2 3 0 0 3 3 3 0 Vms1-associating treble clef domain CCDC50_N PF15295.6 AIN98365.1 - 0.4 10.8 2.6 1.7 8.8 2.7 1.9 1 1 0 1 1 1 0 Coiled-coil domain-containing protein 50 N-terminus PHD_4 PF16866.5 AIN98365.1 - 2.3 8.3 11.3 2.3 8.4 7.6 2.7 2 1 0 2 2 2 0 PHD-finger Zn_Tnp_IS1595 PF12760.7 AIN98365.1 - 5.2 7.1 8.6 0.52 10.3 0.7 3.1 4 0 0 4 4 4 0 Transposase zinc-ribbon domain Rubredoxin_2 PF18073.1 AIN98365.1 - 8.1 6.3 13.7 31 4.4 0.5 4.9 5 0 0 5 5 5 0 Rubredoxin metal binding domain Pkinase PF00069.25 AIN98366.1 - 1.2e-63 214.9 0.0 1.5e-63 214.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 AIN98366.1 - 2.5e-32 112.2 0.0 3.4e-32 111.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 AIN98366.1 - 5.4e-05 22.7 0.0 7.1e-05 22.3 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Fanconi_A_N PF15865.5 AIN98366.1 - 0.068 12.6 0.0 0.089 12.2 0.0 1.1 1 0 0 1 1 1 0 Fanconi anaemia group A protein N terminus MMR_HSR1 PF01926.23 AIN98367.1 - 8.8e-17 61.2 0.0 1.7e-16 60.3 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 AIN98367.1 - 3.2e-08 33.8 0.0 3.7e-06 27.1 0.1 2.4 1 1 0 2 2 2 1 Dynamin family RsgA_GTPase PF03193.16 AIN98367.1 - 0.00022 21.2 0.0 0.014 15.3 0.0 2.4 2 0 0 2 2 2 1 RsgA GTPase GTP_EFTU PF00009.27 AIN98367.1 - 0.0018 17.8 0.0 0.015 14.9 0.0 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AIG1 PF04548.16 AIN98367.1 - 0.0057 16.0 0.0 0.023 14.0 0.0 1.9 1 1 0 1 1 1 1 AIG1 family Septin PF00735.18 AIN98367.1 - 0.008 15.5 0.0 0.014 14.6 0.0 1.3 1 0 0 1 1 1 1 Septin ABC_tran PF00005.27 AIN98367.1 - 0.022 15.3 0.0 0.048 14.2 0.0 1.5 1 0 0 1 1 1 0 ABC transporter cobW PF02492.19 AIN98367.1 - 0.036 13.6 0.0 1.1 8.8 0.0 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain FeoB_N PF02421.18 AIN98367.1 - 0.049 13.2 0.0 0.12 11.8 0.0 1.7 1 1 0 1 1 1 0 Ferrous iron transport protein B Roc PF08477.13 AIN98367.1 - 0.11 12.8 0.0 0.32 11.2 0.0 1.8 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase YbaB_DNA_bd PF02575.16 AIN98368.1 - 9.5e-05 22.6 0.0 0.00019 21.6 0.0 1.4 1 0 0 1 1 1 1 YbaB/EbfC DNA-binding family HIF-1 PF11413.8 AIN98368.1 - 0.026 13.9 0.0 0.049 13.1 0.0 1.4 1 0 0 1 1 1 0 Hypoxia-inducible factor-1 Metal_resist PF13801.6 AIN98368.1 - 0.032 14.4 0.1 0.032 14.4 0.1 2.7 4 0 0 4 4 4 0 Heavy-metal resistance Stealth_CR2 PF11380.8 AIN98369.1 - 1.3e-10 41.4 0.0 1.2e-08 35.1 0.0 2.3 2 0 0 2 2 2 2 Stealth protein CR2, conserved region 2 Stealth_CR3 PF17102.5 AIN98369.1 - 0.012 15.4 0.7 0.036 13.9 0.7 1.9 1 0 0 1 1 1 0 Stealth protein CR3, conserved region 3 Ribosomal_L22 PF00237.19 AIN98370.1 - 6.8e-14 51.9 0.0 1e-13 51.4 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e IQ PF00612.27 AIN98373.1 - 0.58 10.1 4.8 2 8.4 4.8 2.0 1 0 0 1 1 1 0 IQ calmodulin-binding motif Prp18 PF02840.15 AIN98374.1 - 5.6e-12 45.9 0.1 1.1e-11 45.0 0.1 1.4 1 0 0 1 1 1 1 Prp18 domain Arrestin_N PF00339.29 AIN98375.1 - 1.2e-10 41.6 0.0 1.9e-10 41.0 0.0 1.3 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain LDB19 PF13002.7 AIN98375.1 - 0.02 14.6 0.0 0.041 13.6 0.0 1.4 1 0 0 1 1 1 0 Arrestin_N terminal like EF-hand_6 PF13405.6 AIN98376.1 - 1.8e-07 30.5 0.3 0.027 14.4 0.0 3.4 3 0 0 3 3 3 3 EF-hand domain EF-hand_7 PF13499.6 AIN98376.1 - 2.9e-05 24.4 0.1 0.0068 16.8 0.1 3.1 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_8 PF13833.6 AIN98376.1 - 0.00014 21.6 0.1 1.1 9.2 0.1 3.3 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_1 PF00036.32 AIN98376.1 - 0.0024 17.3 0.0 1.2 8.8 0.0 3.1 3 0 0 3 3 3 1 EF hand AAA PF00004.29 AIN98377.1 - 1.6e-13 51.2 0.0 1.5e-07 31.9 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 AIN98377.1 - 3.9e-05 23.7 0.0 9e-05 22.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Pkinase PF00069.25 AIN98378.1 - 2.8e-62 210.5 0.0 3.3e-62 210.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 AIN98378.1 - 3.9e-42 144.3 0.0 4.8e-42 144.0 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 AIN98378.1 - 1.1e-07 31.5 0.0 2e-07 30.7 0.0 1.4 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 AIN98378.1 - 0.00088 18.7 0.1 0.019 14.3 0.0 2.1 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 AIN98378.1 - 0.0012 17.8 0.0 0.0018 17.2 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 AIN98378.1 - 0.044 13.7 0.0 0.092 12.7 0.0 1.5 2 0 0 2 2 2 0 Phosphotransferase enzyme family Haspin_kinase PF12330.8 AIN98378.1 - 0.16 10.9 0.0 0.34 9.8 0.0 1.5 1 0 0 1 1 1 0 Haspin like kinase domain Kinesin PF00225.23 AIN98379.1 - 9e-91 304.2 0.1 3.2e-90 302.4 0.1 1.9 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 AIN98379.1 - 1e-11 45.0 1.1 1.2e-06 28.5 0.0 3.8 4 0 0 4 4 4 2 Microtubule binding TPR_MLP1_2 PF07926.12 AIN98379.1 - 0.00022 21.3 16.1 0.00022 21.3 16.1 7.6 3 2 6 9 9 9 2 TPR/MLP1/MLP2-like protein KELK PF15796.5 AIN98379.1 - 0.004 17.6 2.8 0.004 17.6 2.8 8.3 7 2 1 8 8 8 1 KELK-motif containing domain of MRCK Ser/Thr protein kinase NPR2 PF06218.11 AIN98380.1 - 0.0013 17.6 0.0 0.013 14.3 0.0 2.0 2 0 0 2 2 2 2 Nitrogen permease regulator 2 MRJP PF03022.16 AIN98381.1 - 0.021 14.2 0.0 0.037 13.4 0.0 1.3 1 0 0 1 1 1 0 Major royal jelly protein WD40 PF00400.32 AIN98381.1 - 0.025 15.4 0.7 0.74 10.8 0.0 3.0 3 0 0 3 3 3 0 WD domain, G-beta repeat Ribosomal_60s PF00428.19 AIN98382.1 - 4.1 8.1 6.5 2.2 8.9 2.3 2.9 2 0 0 2 2 2 0 60s Acidic ribosomal protein UAA PF08449.11 AIN98384.1 - 8.2e-32 110.6 9.9 1e-31 110.3 7.7 2.0 2 1 0 2 2 2 1 UAA transporter family EamA PF00892.20 AIN98384.1 - 0.032 14.4 17.0 0.43 10.7 0.1 3.8 3 1 0 3 3 3 0 EamA-like transporter family Kelch_5 PF13854.6 AIN98386.1 - 7.4e-20 70.5 3.1 8.5e-05 22.4 0.3 7.1 6 1 0 6 6 6 4 Kelch motif Kelch_4 PF13418.6 AIN98386.1 - 1.8e-18 66.3 11.1 0.00014 21.8 0.0 6.8 5 2 1 6 6 6 4 Galactose oxidase, central domain Kelch_2 PF07646.15 AIN98386.1 - 5.8e-15 54.6 4.4 0.00013 21.8 0.1 6.5 7 0 0 7 7 7 3 Kelch motif Kelch_3 PF13415.6 AIN98386.1 - 2e-14 53.5 28.9 0.00018 21.7 0.1 8.2 8 1 0 8 8 8 4 Galactose oxidase, central domain Kelch_6 PF13964.6 AIN98386.1 - 4.2e-14 52.2 2.0 0.12 12.7 0.0 6.6 6 1 0 6 6 6 3 Kelch motif Kelch_1 PF01344.25 AIN98386.1 - 6.4e-14 51.3 0.8 0.14 11.8 0.0 7.2 7 0 0 7 7 7 4 Kelch motif LPD23 PF18838.1 AIN98387.1 - 6.7 6.6 8.6 5.7 6.8 0.6 3.5 3 0 0 3 3 3 0 Large polyvalent protein associated domain 23 MFS_1 PF07690.16 AIN98388.1 - 5.8e-22 78.1 25.6 5.8e-22 78.1 25.6 2.3 1 1 1 2 2 2 1 Major Facilitator Superfamily OATP PF03137.20 AIN98388.1 - 2.3e-15 55.9 16.4 9e-10 37.4 2.4 3.8 2 2 2 4 4 4 3 Organic Anion Transporter Polypeptide (OATP) family Sugar_tr PF00083.24 AIN98388.1 - 4.3e-14 52.2 6.3 4.3e-14 52.2 6.3 2.1 2 0 0 2 2 2 1 Sugar (and other) transporter MFS_4 PF06779.14 AIN98388.1 - 2.7e-07 30.2 4.1 2.7e-07 30.2 4.1 3.0 2 1 1 3 3 3 2 Uncharacterised MFS-type transporter YbfB LSM PF01423.22 AIN98389.1 - 9.2e-13 47.7 0.1 1.1e-12 47.4 0.1 1.1 1 0 0 1 1 1 1 LSM domain SP2 PF03014.14 AIN98389.1 - 0.0029 16.1 0.0 0.0029 16.1 0.0 1.0 1 0 0 1 1 1 1 Structural protein 2 Med20 PF08612.11 AIN98389.1 - 0.035 13.5 0.0 0.036 13.4 0.0 1.1 1 0 0 1 1 1 0 TATA-binding related factor (TRF) of subunit 20 of Mediator complex SM-ATX PF14438.6 AIN98389.1 - 0.055 13.6 0.0 0.086 13.0 0.0 1.3 1 0 0 1 1 1 0 Ataxin 2 SM domain SUIM_assoc PF16619.5 AIN98390.1 - 0.28 11.3 0.0 0.28 11.3 0.0 6.6 7 1 0 7 7 7 0 Unstructured region C-term to UIM in Ataxin3 Tmpp129 PF10272.9 AIN98390.1 - 0.63 9.3 4.6 1.1 8.5 4.6 1.3 1 0 0 1 1 1 0 Putative transmembrane protein precursor CRAL_TRIO PF00650.20 AIN98392.1 - 8.1e-14 51.6 0.0 8.8e-13 48.3 0.0 2.5 2 1 0 2 2 2 1 CRAL/TRIO domain zf-C3HC4_3 PF13920.6 AIN98393.1 - 2.2e-08 33.8 10.9 2.2e-08 33.8 10.9 1.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 AIN98393.1 - 0.48 10.3 10.3 1.1 9.1 10.3 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 AIN98393.1 - 1 9.4 14.0 1 9.4 11.0 2.3 2 0 0 2 2 2 0 zinc-RING finger domain AAA_6 PF12774.7 AIN98394.1 - 6.4e-130 432.9 0.0 8.9e-127 422.6 0.0 4.1 2 1 0 2 2 2 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 AIN98394.1 - 7.3e-84 282.2 0.0 3.5e-83 279.9 0.0 2.3 2 0 0 2 2 2 1 Dynein heavy chain, N-terminal region 2 AAA_9 PF12781.7 AIN98394.1 - 3.2e-62 209.6 0.0 1.1e-60 204.5 0.0 2.6 2 0 0 2 2 2 1 ATP-binding dynein motor region AAA_8 PF12780.7 AIN98394.1 - 9.4e-60 202.1 0.0 2.9e-37 128.4 0.0 2.8 2 0 0 2 2 2 2 P-loop containing dynein motor region D4 AAA_7 PF12775.7 AIN98394.1 - 1.7e-44 151.5 0.1 1.2e-37 129.2 0.0 4.7 4 0 0 4 4 4 2 P-loop containing dynein motor region MT PF12777.7 AIN98394.1 - 1.7e-35 122.7 0.8 2.7e-35 122.0 0.8 1.3 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_5 PF07728.14 AIN98394.1 - 7.2e-29 100.6 2.0 3.7e-10 39.9 0.1 7.2 5 2 0 5 5 5 4 AAA domain (dynein-related subfamily) Dynein_heavy PF03028.15 AIN98394.1 - 6.3e-23 81.1 0.0 1e-21 77.2 0.0 3.1 2 0 0 2 2 2 1 Dynein heavy chain region D6 P-loop domain Dynein_C PF18199.1 AIN98394.1 - 1.7e-21 76.8 0.0 4.8e-21 75.3 0.0 1.8 1 0 0 1 1 1 1 Dynein heavy chain C-terminal domain AAA_lid_11 PF18198.1 AIN98394.1 - 3.6e-21 75.7 0.0 8.1e-21 74.5 0.0 1.6 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain AAA PF00004.29 AIN98394.1 - 8.5e-20 71.5 0.0 1.9e-06 28.3 0.0 5.1 4 0 0 4 4 4 3 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 AIN98394.1 - 1.5e-14 54.4 10.4 8e-06 26.2 0.0 7.4 7 0 0 7 7 7 2 AAA domain AAA_16 PF13191.6 AIN98394.1 - 4.1e-11 43.6 12.1 0.071 13.5 0.0 7.5 7 0 0 7 7 4 4 AAA ATPase domain AAA_18 PF13238.6 AIN98394.1 - 1.3e-06 29.0 0.0 9.6 6.8 0.0 5.5 4 0 0 4 4 4 0 AAA domain AAA_24 PF13479.6 AIN98394.1 - 1.4e-06 28.2 0.1 2 8.1 0.0 4.4 4 0 0 4 4 4 2 AAA domain AAA_25 PF13481.6 AIN98394.1 - 2e-06 27.5 0.3 0.1 12.2 0.0 4.1 3 0 0 3 3 3 2 AAA domain AAA_33 PF13671.6 AIN98394.1 - 2.9e-06 27.5 5.5 0.19 11.9 0.0 5.3 5 0 0 5 5 4 2 AAA domain T2SSE PF00437.20 AIN98394.1 - 5.9e-06 25.5 0.0 0.44 9.5 0.0 4.3 4 0 0 4 4 4 1 Type II/IV secretion system protein IstB_IS21 PF01695.17 AIN98394.1 - 1.4e-05 24.9 2.0 0.046 13.5 0.0 4.4 4 0 0 4 4 4 1 IstB-like ATP binding protein AAA_30 PF13604.6 AIN98394.1 - 2.4e-05 24.1 5.3 0.47 10.1 0.2 4.5 4 0 0 4 4 4 2 AAA domain FtsK_SpoIIIE PF01580.18 AIN98394.1 - 7e-05 22.3 1.4 0.39 10.0 0.0 4.0 4 0 0 4 4 3 2 FtsK/SpoIIIE family AAA_lid_1 PF17857.1 AIN98394.1 - 8e-05 22.8 0.0 0.00031 20.9 0.0 2.1 1 0 0 1 1 1 1 AAA+ lid domain ABC_tran PF00005.27 AIN98394.1 - 0.00013 22.5 0.2 0.43 11.1 0.0 4.5 4 0 0 4 4 3 1 ABC transporter Sigma54_activat PF00158.26 AIN98394.1 - 0.00018 21.2 0.0 0.26 11.0 0.0 3.4 3 0 0 3 3 3 1 Sigma-54 interaction domain RNA_helicase PF00910.22 AIN98394.1 - 0.00041 20.7 0.2 5.2 7.5 0.0 4.6 4 0 0 4 4 4 0 RNA helicase AAA_19 PF13245.6 AIN98394.1 - 0.0011 19.3 7.4 3.2 8.1 0.1 5.3 5 0 0 5 5 4 1 AAA domain RsgA_GTPase PF03193.16 AIN98394.1 - 0.0029 17.5 0.0 16 5.4 0.0 3.8 3 0 0 3 3 3 0 RsgA GTPase AAA_29 PF13555.6 AIN98394.1 - 0.0029 17.3 4.5 1.4 8.7 0.0 4.5 4 0 0 4 4 4 1 P-loop containing region of AAA domain RuvB_N PF05496.12 AIN98394.1 - 0.0053 16.5 0.6 1.5 8.6 0.0 3.6 3 0 0 3 3 3 1 Holliday junction DNA helicase RuvB P-loop domain AAA_28 PF13521.6 AIN98394.1 - 0.0054 17.0 0.7 51 4.1 0.1 4.9 4 0 0 4 4 4 0 AAA domain Mg_chelatase PF01078.21 AIN98394.1 - 0.0077 15.6 7.7 0.25 10.7 0.0 3.9 4 0 0 4 4 3 1 Magnesium chelatase, subunit ChlI Dynein_AAA_lid PF17852.1 AIN98394.1 - 0.031 14.4 0.1 0.1 12.7 0.1 1.9 1 0 0 1 1 1 0 Dynein heavy chain AAA lid domain POT1PC PF16686.5 AIN98394.1 - 0.048 13.5 0.0 0.15 11.9 0.0 1.8 1 0 0 1 1 1 0 ssDNA-binding domain of telomere protection protein TrwB_AAD_bind PF10412.9 AIN98394.1 - 0.068 12.1 2.3 2.9 6.7 0.3 3.2 3 0 0 3 3 3 0 Type IV secretion-system coupling protein DNA-binding domain SRP54 PF00448.22 AIN98394.1 - 0.094 12.3 2.3 3.2 7.3 0.2 3.6 4 0 0 4 4 4 0 SRP54-type protein, GTPase domain Rad17 PF03215.15 AIN98394.1 - 0.13 12.2 0.1 39 4.1 0.0 3.7 4 0 0 4 4 4 0 Rad17 P-loop domain NB-ARC PF00931.22 AIN98394.1 - 0.15 11.2 0.4 3.5 6.8 0.1 3.0 3 0 0 3 3 3 0 NB-ARC domain AAA_11 PF13086.6 AIN98394.1 - 0.16 11.8 13.1 2.1 8.1 0.0 4.8 5 0 0 5 5 4 0 AAA domain CbiA PF01656.23 AIN98394.1 - 0.38 10.8 1.8 34 4.5 0.1 3.8 3 0 0 3 3 3 0 CobQ/CobB/MinD/ParA nucleotide binding domain PhoH PF02562.16 AIN98394.1 - 0.48 9.8 8.4 0.12 11.8 0.1 3.3 4 0 0 4 4 3 0 PhoH-like protein Noelin-1 PF12308.8 AIN98394.1 - 2.4 8.2 5.3 81 3.3 0.4 4.3 3 0 0 3 3 3 0 Neurogenesis glycoprotein Lactamase_B_2 PF12706.7 AIN98395.1 - 2.3e-13 50.1 0.0 2.1e-09 37.2 0.0 2.4 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 AIN98395.1 - 6.7e-05 23.0 0.3 0.00015 21.8 0.3 1.7 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Adap_comp_sub PF00928.21 AIN98397.1 - 7.7e-83 277.9 0.1 9.6e-83 277.6 0.1 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 AIN98397.1 - 0.0055 16.6 0.3 0.0097 15.8 0.3 1.4 1 0 0 1 1 1 1 Clathrin adaptor complex small chain PhetRS_B1 PF18262.1 AIN98397.1 - 0.049 13.9 0.0 0.12 12.6 0.0 1.7 1 0 0 1 1 1 0 Phe-tRNA synthetase beta subunit B1 domain Pkinase PF00069.25 AIN98398.1 - 2.3e-14 53.4 0.0 5e-07 29.4 0.0 2.4 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 AIN98398.1 - 0.001 18.4 0.0 0.33 10.2 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase VanW PF04294.13 AIN98398.1 - 0.019 14.6 0.1 0.05 13.3 0.1 1.8 1 0 0 1 1 1 0 VanW like protein Pkinase PF00069.25 AIN98400.1 - 1.4e-22 80.3 0.0 1.1e-17 64.3 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 AIN98400.1 - 3e-08 33.3 0.0 3.1e-07 30.0 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase ChaC PF04752.12 AIN98401.1 - 4.4e-42 144.2 0.0 4.7e-41 140.8 0.0 2.0 1 1 0 1 1 1 1 ChaC-like protein WD40 PF00400.32 AIN98402.1 - 4e-07 30.6 0.4 0.00061 20.5 0.0 3.9 3 0 0 3 3 3 2 WD domain, G-beta repeat SHS2_Rpb7-N PF03876.17 AIN98404.1 - 0.094 13.1 0.0 20 5.6 0.0 2.7 2 0 0 2 2 2 0 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 GTP_EFTU PF00009.27 AIN98405.1 - 2.7e-33 115.1 3.2 1.5e-31 109.5 3.2 2.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 AIN98405.1 - 5.9e-10 39.2 0.1 1.2e-09 38.2 0.1 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase IF-2 PF11987.8 AIN98405.1 - 0.0002 21.4 0.0 0.00054 20.0 0.0 1.8 1 0 0 1 1 1 1 Translation-initiation factor 2 FeoB_N PF02421.18 AIN98405.1 - 0.00022 20.8 0.0 0.00043 19.8 0.0 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B SRPRB PF09439.10 AIN98405.1 - 0.00022 20.7 0.0 0.00046 19.7 0.0 1.4 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit PduV-EutP PF10662.9 AIN98405.1 - 0.00039 20.2 0.0 0.0012 18.6 0.0 1.8 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation Dynamin_N PF00350.23 AIN98405.1 - 0.0014 18.7 2.4 0.82 9.7 0.0 3.2 2 1 1 3 3 3 2 Dynamin family RsgA_GTPase PF03193.16 AIN98405.1 - 0.005 16.8 0.0 4.7 7.1 0.0 2.5 1 1 1 2 2 2 2 RsgA GTPase Roc PF08477.13 AIN98405.1 - 0.011 15.9 0.0 0.022 14.9 0.0 1.5 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase WD40 PF00400.32 AIN98406.1 - 5.4e-13 49.2 15.1 0.0041 17.9 0.2 6.9 6 1 0 6 6 6 6 WD domain, G-beta repeat MORN PF02493.20 AIN98408.1 - 3.7e-07 29.6 11.7 0.056 13.4 1.4 3.5 3 0 0 3 3 3 3 MORN repeat CPSase_L_D2 PF02786.17 AIN98409.1 - 0.018 14.5 0.1 0.035 13.6 0.1 1.4 1 0 0 1 1 1 0 Carbamoyl-phosphate synthase L chain, ATP binding domain Ribonuc_red_sm PF00268.21 AIN98410.1 - 5e-111 370.6 0.1 6.1e-111 370.3 0.1 1.0 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain NMT PF01233.19 AIN98410.1 - 0.11 12.4 0.0 0.2 11.5 0.0 1.3 1 0 0 1 1 1 0 Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain Atg8 PF02991.16 AIN98411.1 - 1.4e-11 44.5 0.0 7.9e-11 42.1 0.0 1.9 2 0 0 2 2 2 1 Autophagy protein Atg8 ubiquitin like APG12 PF04110.13 AIN98411.1 - 0.0004 20.7 0.0 0.00059 20.2 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 ING PF12998.7 AIN98413.1 - 0.12 12.9 0.4 0.35 11.5 0.1 1.8 2 0 0 2 2 2 0 Inhibitor of growth proteins N-terminal histone-binding CR6_interact PF10147.9 AIN98413.1 - 0.19 11.5 2.6 0.1 12.3 0.2 1.7 2 0 0 2 2 2 0 Growth arrest and DNA-damage-inducible proteins-interacting protein 1 Suppressor_APC PF11414.8 AIN98413.1 - 3.4 7.8 7.6 2 8.5 3.2 2.8 2 1 1 3 3 3 0 Adenomatous polyposis coli tumour suppressor protein HAP1_N PF04849.13 AIN98414.1 - 0.0056 15.9 4.3 0.0056 15.9 4.3 3.8 4 0 0 4 4 4 1 HAP1 N-terminal conserved region Golgin_A5 PF09787.9 AIN98414.1 - 0.02 14.4 30.3 0.067 12.6 0.5 3.9 4 0 0 4 4 4 0 Golgin subfamily A member 5 Spc7 PF08317.11 AIN98414.1 - 0.19 10.6 30.8 0.34 9.7 3.2 4.0 4 0 0 4 4 4 0 Spc7 kinetochore protein Spc29 PF17082.5 AIN98414.1 - 5.3 6.8 12.0 5.6 6.7 0.0 4.4 4 1 0 4 4 4 0 Spindle Pole Component 29 betaPIX_CC PF16523.5 AIN98414.1 - 6.7 6.6 7.7 12 5.9 2.9 2.8 2 0 0 2 2 2 0 betaPIX coiled coil Fez1 PF06818.15 AIN98414.1 - 9.6 6.6 23.8 7.8 6.9 5.1 4.3 4 0 0 4 4 4 0 Fez1 COMP PF11598.8 AIN98415.1 - 0.017 15.6 6.0 0.41 11.1 0.1 3.9 4 0 0 4 4 4 0 Cartilage oligomeric matrix protein LPP PF04728.13 AIN98415.1 - 1.7 9.1 6.2 35 4.9 0.1 3.9 3 0 0 3 3 3 0 Lipoprotein leucine-zipper DUF2937 PF11157.8 AIN98415.1 - 5.1 6.8 8.6 0.64 9.7 1.3 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2937) Methyltransf_28 PF02636.17 AIN98417.1 - 2e-40 139.1 0.0 2.8e-40 138.6 0.0 1.1 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_25 PF13649.6 AIN98417.1 - 0.0041 17.8 0.0 0.01 16.5 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 AIN98417.1 - 0.0046 16.8 0.0 0.0077 16.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain RrnaAD PF00398.20 AIN98417.1 - 0.0059 15.7 0.0 0.0097 15.0 0.0 1.3 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_12 PF08242.12 AIN98417.1 - 0.013 16.2 0.0 0.025 15.3 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Peptidase_C62 PF12380.8 AIN98417.1 - 0.14 11.2 0.0 0.23 10.6 0.0 1.3 1 0 0 1 1 1 0 Gill-associated viral 3C-like peptidase DHHC PF01529.20 AIN98418.1 - 4.1e-32 111.1 8.9 4.1e-32 111.1 8.9 1.9 2 0 0 2 2 2 1 DHHC palmitoyltransferase DUF3949 PF13133.6 AIN98418.1 - 1.6 9.3 3.3 0.61 10.6 0.6 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3949) DUF4690 PF15756.5 AIN98418.1 - 2.2 9.0 3.9 8.4 7.1 3.9 1.9 1 0 0 1 1 1 0 Small Novel Rich in Cartilage polyprenyl_synt PF00348.17 AIN98419.1 - 1.7e-74 250.1 0.7 2.1e-74 249.9 0.7 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase YhzD PF14120.6 AIN98420.1 - 0.081 13.1 0.5 0.34 11.1 0.5 2.1 1 0 0 1 1 1 0 YhzD-like protein Ribosomal_L28e PF01778.17 AIN98421.1 - 1.6e-28 99.8 0.2 3.2e-28 98.8 0.0 1.5 2 0 0 2 2 2 1 Ribosomal L28e protein family Mak16 PF04874.14 AIN98421.1 - 2.8e-15 56.7 19.1 2.8e-15 56.7 19.1 2.0 1 1 1 2 2 2 1 Mak16 protein C-terminal region Gag_p24 PF00607.20 AIN98421.1 - 0.054 13.4 0.2 0.097 12.5 0.1 1.5 1 1 1 2 2 2 0 gag gene protein p24 (core nucleocapsid protein) CDC45 PF02724.14 AIN98421.1 - 0.47 8.7 10.9 0.28 9.5 9.3 1.3 1 1 0 1 1 1 0 CDC45-like protein MORN PF02493.20 AIN98423.1 - 7.8e-47 154.4 82.0 6.1e-05 22.7 0.2 13.0 13 0 0 13 13 13 12 MORN repeat EF-hand_1 PF00036.32 AIN98424.1 - 8.4e-26 87.6 7.5 2.8e-08 32.7 0.4 4.1 4 0 0 4 4 4 3 EF hand EF-hand_7 PF13499.6 AIN98424.1 - 1.2e-22 80.1 1.2 4.8e-11 42.9 0.3 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 AIN98424.1 - 1.8e-19 67.9 4.4 4.9e-07 29.2 0.1 4.0 3 1 0 3 3 3 3 EF-hand domain EF-hand_8 PF13833.6 AIN98424.1 - 1e-17 63.7 6.7 6.9e-10 38.6 0.4 3.9 1 1 3 4 4 4 4 EF-hand domain pair EF-hand_5 PF13202.6 AIN98424.1 - 1.5e-17 62.2 6.8 1.7e-05 24.1 0.1 3.4 3 0 0 3 3 3 3 EF hand EF-hand_9 PF14658.6 AIN98424.1 - 1.4e-07 31.8 0.0 1.6e-06 28.3 0.0 2.1 2 0 0 2 2 2 1 EF-hand domain EF-hand_4 PF12763.7 AIN98424.1 - 2.7e-07 30.5 2.4 0.051 13.5 0.9 3.1 1 1 2 3 3 3 3 Cytoskeletal-regulatory complex EF hand EFhand_Ca_insen PF08726.10 AIN98424.1 - 0.02 15.0 0.1 9.6 6.4 0.0 2.8 2 1 0 2 2 2 0 Ca2+ insensitive EF hand DUF3911 PF13050.6 AIN98424.1 - 0.094 12.8 0.2 0.2 11.8 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3911) SPARC_Ca_bdg PF10591.9 AIN98424.1 - 0.096 13.0 0.0 0.29 11.5 0.0 1.8 2 0 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region MIP PF00230.20 AIN98425.1 - 4.6e-21 75.6 20.4 9e-20 71.3 19.7 2.6 1 1 1 2 2 2 2 Major intrinsic protein FKBP_C PF00254.28 AIN98426.1 - 2.1e-29 101.7 0.0 2.4e-29 101.5 0.0 1.1 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase Pro_isomerase PF00160.21 AIN98428.1 - 6.9e-35 120.7 0.0 8.8e-35 120.3 0.0 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD EF-hand_8 PF13833.6 AIN98429.1 - 4.6e-07 29.6 0.1 2.6e-06 27.2 0.0 2.2 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_7 PF13499.6 AIN98429.1 - 6.3e-05 23.4 0.0 0.007 16.8 0.0 2.4 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 AIN98429.1 - 0.014 15.3 0.0 1.9 8.7 0.0 3.2 3 1 0 3 3 3 0 EF-hand domain EF-hand_1 PF00036.32 AIN98429.1 - 0.028 14.0 0.0 9.9 6.0 0.0 3.3 3 1 0 3 3 3 0 EF hand TPR_2 PF07719.17 AIN98430.1 - 0.0046 17.0 0.6 1.6 9.1 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat RE_MjaI PF09568.10 AIN98430.1 - 0.085 12.7 0.1 0.34 10.7 0.0 1.8 2 0 0 2 2 2 0 MjaI restriction endonuclease TPR_12 PF13424.6 AIN98430.1 - 0.24 11.7 4.9 2.1 8.7 0.1 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat MAM33 PF02330.16 AIN98431.1 - 2.3e-21 76.8 0.2 2.4e-19 70.1 0.2 2.4 1 1 0 1 1 1 1 Mitochondrial glycoprotein RE_MjaI PF09568.10 AIN98432.1 - 0.085 12.7 0.0 0.13 12.1 0.0 1.1 1 0 0 1 1 1 0 MjaI restriction endonuclease Metallophos PF00149.28 AIN98433.1 - 5.7e-14 53.1 0.1 7.8e-14 52.7 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase FBPase_2 PF06874.11 AIN98433.1 - 0.067 11.5 0.1 4.1 5.6 0.0 2.8 3 0 0 3 3 3 0 Firmicute fructose-1,6-bisphosphatase HA2 PF04408.23 AIN98434.1 - 1.1e-17 64.3 0.0 2.6e-17 63.1 0.0 1.6 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.31 AIN98434.1 - 2.2e-14 53.7 0.0 5.2e-14 52.5 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 AIN98434.1 - 3.8e-07 30.0 0.0 9.1e-07 28.8 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 AIN98434.1 - 1.8e-06 28.3 0.0 5.9e-06 26.6 0.0 1.9 1 0 0 1 1 1 1 AAA domain R3H PF01424.22 AIN98434.1 - 0.0051 16.8 0.0 0.017 15.1 0.0 2.0 1 0 0 1 1 1 1 R3H domain AAA_19 PF13245.6 AIN98434.1 - 0.0079 16.5 0.0 0.028 14.7 0.0 1.9 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 AIN98434.1 - 0.016 14.3 0.0 0.028 13.5 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein Ribosomal_L14e PF01929.17 AIN98435.1 - 1.7e-18 66.9 1.2 1.7e-18 66.9 1.2 2.2 2 1 0 2 2 2 1 Ribosomal protein L14 KOW PF00467.29 AIN98435.1 - 8.6e-05 22.3 1.1 0.00018 21.4 1.1 1.5 1 0 0 1 1 1 1 KOW motif CoaE PF01121.20 AIN98436.1 - 1.9e-42 145.0 0.0 3.6e-42 144.0 0.0 1.4 1 1 0 1 1 1 1 Dephospho-CoA kinase AAA_18 PF13238.6 AIN98436.1 - 6.2e-05 23.6 0.4 0.0042 17.6 0.4 2.8 1 1 1 2 2 2 1 AAA domain Cytidylate_kin2 PF13189.6 AIN98436.1 - 0.0084 16.3 1.0 3.1 7.9 0.0 2.4 2 1 0 2 2 2 2 Cytidylate kinase-like family PRK PF00485.18 AIN98436.1 - 0.055 13.2 0.1 0.15 11.7 0.0 1.7 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family DndE PF08870.11 AIN98436.1 - 0.068 13.4 0.0 0.14 12.5 0.0 1.4 1 0 0 1 1 1 0 DNA sulphur modification protein DndE AAA_33 PF13671.6 AIN98436.1 - 0.094 12.9 0.0 1.5 9.0 0.0 2.5 1 1 0 1 1 1 0 AAA domain SKI PF01202.22 AIN98436.1 - 0.098 12.8 0.0 0.55 10.3 0.0 1.9 2 0 0 2 2 2 0 Shikimate kinase Cytidylate_kin PF02224.18 AIN98436.1 - 0.1 12.3 0.2 1 9.1 0.0 2.0 2 0 0 2 2 2 0 Cytidylate kinase tRNA-synt_2c PF01411.19 AIN98437.1 - 3.8e-192 639.7 0.0 5e-192 639.3 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (A) tRNA_SAD PF07973.14 AIN98437.1 - 1.2e-10 41.3 0.0 3.1e-10 40.0 0.0 1.8 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain DHHA1 PF02272.19 AIN98437.1 - 0.00015 22.2 4.1 0.00023 21.6 1.6 2.6 1 1 1 2 2 2 1 DHHA1 domain FliMN_C PF01052.20 AIN98438.1 - 0.017 15.1 0.0 0.043 13.8 0.0 1.6 1 0 0 1 1 1 0 Type III flagellar switch regulator (C-ring) FliN C-term Ribosomal_L14e PF01929.17 AIN98439.1 - 1.7e-18 66.9 1.2 1.7e-18 66.9 1.2 2.2 2 1 0 2 2 2 1 Ribosomal protein L14 KOW PF00467.29 AIN98439.1 - 8.6e-05 22.3 1.1 0.00018 21.4 1.1 1.5 1 0 0 1 1 1 1 KOW motif Bile_Hydr_Trans PF04775.14 AIN98440.1 - 0.16 12.0 0.0 0.29 11.2 0.0 1.3 1 0 0 1 1 1 0 Acyl-CoA thioester hydrolase/BAAT N-terminal region DUF1358 PF07096.11 AIN98441.1 - 0.12 12.4 0.0 0.28 11.2 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1358) RNase_PH PF01138.21 AIN98442.1 - 1.9e-08 34.9 0.0 4.2e-08 33.8 0.0 1.6 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 AIN98442.1 - 0.00011 22.1 0.2 0.00029 20.8 0.2 1.6 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 NAD_binding_5 PF07994.12 AIN98442.1 - 0.044 13.2 0.1 0.068 12.5 0.1 1.2 1 0 0 1 1 1 0 Myo-inositol-1-phosphate synthase Metallophos PF00149.28 AIN98444.1 - 1.4e-10 42.1 0.0 2.1e-10 41.4 0.0 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 AIN98444.1 - 1e-05 25.8 0.0 1.9e-05 24.9 0.0 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain ASH PF15780.5 AIN98446.1 - 1.3e-37 127.9 27.2 1.9e-05 24.8 0.0 16.5 16 0 0 16 16 16 11 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin TMEM131_like PF12371.8 AIN98446.1 - 6.3e-11 42.4 2.7 0.93 9.8 0.1 9.7 10 0 0 10 10 10 3 Transmembrane protein 131-like Motile_Sperm PF00635.26 AIN98446.1 - 2e-10 40.4 0.0 2.7 7.9 0.0 8.5 10 0 0 10 10 10 4 MSP (Major sperm protein) domain PapD-like PF14874.6 AIN98446.1 - 1.1e-05 25.5 11.8 0.00039 20.5 0.1 7.3 7 2 1 8 8 8 1 Flagellar-associated PapD-like CAF1 PF04857.20 AIN98447.1 - 2.6e-22 79.4 2.6 4.3e-11 42.6 0.1 2.5 1 1 1 2 2 2 2 CAF1 family ribonuclease cobW PF02492.19 AIN98449.1 - 3.5e-27 95.1 0.0 5e-27 94.6 0.0 1.2 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.14 AIN98449.1 - 0.016 15.1 0.0 0.05 13.5 0.0 1.7 1 1 0 1 1 1 0 Cobalamin synthesis protein cobW C-terminal domain AAA_22 PF13401.6 AIN98449.1 - 0.065 13.5 0.0 0.2 11.9 0.0 1.8 1 0 0 1 1 1 0 AAA domain MobB PF03205.14 AIN98449.1 - 0.068 13.1 0.0 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B ABC_tran PF00005.27 AIN98449.1 - 0.12 12.8 0.0 0.21 12.1 0.0 1.3 1 0 0 1 1 1 0 ABC transporter AAA_33 PF13671.6 AIN98449.1 - 0.13 12.4 0.0 0.26 11.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain SRP54 PF00448.22 AIN98449.1 - 0.2 11.3 0.0 0.33 10.5 0.0 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain TrwB_AAD_bind PF10412.9 AIN98449.1 - 0.21 10.5 0.0 0.36 9.7 0.0 1.3 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain RIIa PF02197.17 AIN98450.1 - 0.0037 16.9 0.1 0.013 15.2 0.1 1.9 1 0 0 1 1 1 1 Regulatory subunit of type II PKA R-subunit RINT1_TIP1 PF04437.13 AIN98450.1 - 0.0088 15.0 0.0 0.014 14.3 0.0 1.3 1 0 0 1 1 1 1 RINT-1 / TIP-1 family PI-PLC-X PF00388.19 AIN98452.1 - 1.2e-58 196.8 0.0 2.5e-58 195.8 0.0 1.6 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.19 AIN98452.1 - 6.8e-32 110.2 0.0 2.5e-31 108.4 0.0 2.0 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain C2 PF00168.30 AIN98452.1 - 7.8e-07 29.3 0.0 1.6e-06 28.3 0.0 1.5 1 0 0 1 1 1 1 C2 domain EF-hand_7 PF13499.6 AIN98452.1 - 5.3e-06 26.8 0.7 2.1e-05 24.8 0.1 2.5 2 1 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.32 AIN98452.1 - 0.00017 20.9 0.0 0.0019 17.6 0.0 2.8 2 1 1 3 3 3 1 EF hand EF-hand_6 PF13405.6 AIN98452.1 - 0.0027 17.5 0.0 0.094 12.7 0.0 3.1 2 1 0 2 2 2 1 EF-hand domain EF-hand_5 PF13202.6 AIN98452.1 - 0.18 11.4 0.0 0.51 9.9 0.0 1.8 1 0 0 1 1 1 0 EF hand DUF4995 PF16386.5 AIN98453.1 - 0.056 13.5 0.5 0.15 12.1 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function Inhibitor_I67 PF11405.8 AIN98453.1 - 5.5 7.3 7.2 3.2 8.1 1.1 2.7 3 0 0 3 3 3 0 Bromelain inhibitor VI CNOT11 PF10155.9 AIN98454.1 - 0.00025 21.2 0.3 0.0011 19.1 0.0 2.0 2 0 0 2 2 2 1 CCR4-NOT transcription complex subunit 11 DUF445 PF04286.12 AIN98454.1 - 0.0015 18.4 1.7 0.0025 17.7 0.1 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF445) UTP15_C PF09384.10 AIN98456.1 - 3.6e-31 107.8 0.3 5.7e-31 107.2 0.3 1.3 1 0 0 1 1 1 1 UTP15 C terminal WD40 PF00400.32 AIN98456.1 - 1e-13 51.5 1.8 0.012 16.4 0.1 5.6 6 0 0 6 6 6 3 WD domain, G-beta repeat P34-Arc PF04045.14 AIN98456.1 - 0.047 13.4 0.6 0.17 11.6 0.0 1.9 2 0 0 2 2 2 0 Arp2/3 complex, 34 kD subunit p34-Arc AhpC-TSA PF00578.21 AIN98457.1 - 8.7e-38 129.0 0.0 1.2e-37 128.6 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 AIN98457.1 - 3.3e-16 59.3 0.0 4.2e-16 59.0 0.0 1.1 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.9 AIN98457.1 - 4.6e-08 32.8 0.1 8.9e-08 31.9 0.1 1.5 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin SCO1-SenC PF02630.14 AIN98457.1 - 0.041 13.8 0.0 0.097 12.6 0.0 1.5 2 0 0 2 2 2 0 SCO1/SenC EIAV_GP90 PF00971.18 AIN98457.1 - 0.09 11.4 0.0 0.11 11.1 0.0 1.1 1 0 0 1 1 1 0 EIAV coat protein, gp90 Pro_isomerase PF00160.21 AIN98458.1 - 1.7e-45 155.2 0.0 2.9e-45 154.4 0.0 1.4 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Arginase PF00491.21 AIN98460.1 - 5.2e-27 95.1 0.0 7.9e-27 94.5 0.0 1.3 1 1 0 1 1 1 1 Arginase family Tropomyosin_1 PF12718.7 AIN98461.1 - 3.5e-05 24.0 3.3 3.5e-05 24.0 3.3 3.5 1 1 1 3 3 3 1 Tropomyosin like Lebercilin PF15619.6 AIN98461.1 - 0.002 17.8 23.3 0.002 17.8 23.3 4.0 3 2 0 3 3 3 1 Ciliary protein causing Leber congenital amaurosis disease Sorting_nexin PF03700.13 AIN98461.1 - 0.45 11.1 6.9 0.82 10.2 6.2 1.9 1 1 0 1 1 1 0 Sorting nexin, N-terminal domain Spc7 PF08317.11 AIN98461.1 - 0.64 8.8 40.6 0.23 10.3 28.6 2.9 1 1 1 2 2 2 0 Spc7 kinetochore protein DUF1664 PF07889.12 AIN98461.1 - 0.7 9.9 24.0 0.032 14.3 6.2 4.0 2 1 2 4 4 4 0 Protein of unknown function (DUF1664) V_ATPase_I PF01496.19 AIN98461.1 - 2.7 5.8 27.7 0.052 11.5 17.2 2.2 1 1 1 2 2 2 0 V-type ATPase 116kDa subunit family Seryl_tRNA_N PF02403.22 AIN98461.1 - 3.3 8.0 37.7 2.4 8.4 0.3 4.5 1 1 1 4 4 4 0 Seryl-tRNA synthetase N-terminal domain Gal4_dimer PF03902.13 AIN98461.1 - 6.6 7.0 11.1 0.24 11.6 0.5 3.3 3 1 0 3 3 3 0 Gal4-like dimerisation domain DUF4375 PF14300.6 AIN98461.1 - 7.1 6.9 8.6 6.6 7.0 5.4 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4375) DUF3810 PF12725.7 AIN98461.1 - 7.4 5.8 9.9 1.8 7.9 6.2 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF3810) RMI1_N PF08585.12 AIN98462.1 - 2.2e-25 89.7 0.3 7e-25 88.1 0.3 1.7 1 1 0 1 1 1 1 RecQ mediated genome instability protein Methyltransf_16 PF10294.9 AIN98463.1 - 3.5e-17 62.7 0.0 4.9e-17 62.2 0.0 1.1 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_31 PF13847.6 AIN98463.1 - 3.1e-08 33.6 0.0 4.6e-08 33.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 AIN98463.1 - 4.1e-08 33.9 0.0 3.4e-07 30.9 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 AIN98463.1 - 4.6e-08 33.7 0.0 8.2e-08 32.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 AIN98463.1 - 3.2e-05 23.6 0.0 4.4e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain tRNA_U5-meth_tr PF05958.11 AIN98463.1 - 5.9e-05 22.2 0.0 7.9e-05 21.8 0.0 1.1 1 0 0 1 1 1 1 tRNA (Uracil-5-)-methyltransferase Methyltransf_11 PF08241.12 AIN98463.1 - 0.00028 21.5 0.0 0.00066 20.3 0.0 1.7 2 0 0 2 2 1 1 Methyltransferase domain PrmA PF06325.13 AIN98463.1 - 0.00082 18.9 0.0 0.0011 18.4 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) NodS PF05401.11 AIN98463.1 - 0.0016 18.1 0.0 0.0025 17.5 0.0 1.2 1 0 0 1 1 1 1 Nodulation protein S (NodS) Methyltransf_23 PF13489.6 AIN98463.1 - 0.0054 16.6 0.0 0.0073 16.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.11 AIN98463.1 - 0.02 13.9 0.0 0.03 13.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) RrnaAD PF00398.20 AIN98463.1 - 0.067 12.2 0.0 0.095 11.7 0.0 1.1 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Met_10 PF02475.16 AIN98463.1 - 0.17 11.6 0.0 0.23 11.2 0.0 1.2 1 0 0 1 1 1 0 Met-10+ like-protein NTP_transferase PF00483.23 AIN98464.1 - 1.1e-47 162.7 0.0 1.4e-47 162.3 0.0 1.1 1 0 0 1 1 1 1 Nucleotidyl transferase Hexapep PF00132.24 AIN98464.1 - 7.4e-12 44.5 13.8 5.4e-06 25.9 1.3 3.7 1 1 2 3 3 3 3 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.7 AIN98464.1 - 2.1e-11 44.5 0.0 2.9e-11 44.0 0.0 1.2 1 0 0 1 1 1 1 MobA-like NTP transferase domain Fucokinase PF07959.12 AIN98464.1 - 4.2e-07 29.3 0.2 0.0017 17.4 0.0 2.3 1 1 1 2 2 2 2 L-fucokinase DUF4954 PF16314.5 AIN98464.1 - 0.0087 14.2 1.6 0.013 13.6 1.6 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4954) Hexapep_2 PF14602.6 AIN98464.1 - 0.025 14.3 18.3 0.21 11.4 0.3 3.8 3 1 0 3 3 3 0 Hexapeptide repeat of succinyl-transferase CTP_transf_3 PF02348.19 AIN98464.1 - 0.061 13.2 0.0 0.089 12.7 0.0 1.2 1 0 0 1 1 1 0 Cytidylyltransferase Beach PF02138.18 AIN98465.1 - 4.9e-99 331.2 0.0 7.7e-99 330.5 0.0 1.3 1 0 0 1 1 1 1 Beige/BEACH domain PH_BEACH PF14844.6 AIN98465.1 - 0.037 14.1 0.0 0.1 12.7 0.0 1.7 1 0 0 1 1 1 0 PH domain associated with Beige/BEACH Pro_isomerase PF00160.21 AIN98466.1 - 3.2e-13 50.2 0.0 3.9e-13 50.0 0.0 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD ATP-synt_C PF00137.21 AIN98467.1 - 8.3e-26 90.1 35.1 2.8e-15 56.4 14.6 2.3 2 0 0 2 2 2 2 ATP synthase subunit C DUF4064 PF13273.6 AIN98467.1 - 0.35 11.1 17.5 0.66 10.3 8.9 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF4064) GerA PF03323.13 AIN98467.1 - 2 6.8 9.1 2.1 6.7 0.9 2.1 2 0 0 2 2 2 0 Bacillus/Clostridium GerA spore germination protein Abhydrolase_6 PF12697.7 AIN98468.1 - 6.8e-16 59.5 2.8 1.1e-15 58.8 2.8 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 AIN98468.1 - 9.8e-15 54.9 0.1 2.5e-14 53.5 0.1 1.7 2 0 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 AIN98468.1 - 1.4e-10 40.8 0.0 2.6e-10 40.0 0.0 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Ser_hydrolase PF06821.13 AIN98468.1 - 0.0028 17.5 0.1 0.0067 16.3 0.0 1.7 2 0 0 2 2 2 1 Serine hydrolase LIDHydrolase PF10230.9 AIN98468.1 - 0.051 13.1 0.0 0.084 12.4 0.0 1.4 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase Glyco_transf_4 PF13439.6 AIN98468.1 - 0.21 11.6 2.7 4.4 7.3 0.0 2.9 2 1 1 3 3 3 0 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.6 AIN98468.1 - 0.4 11.1 5.0 6.8 7.1 0.0 2.8 2 1 1 3 3 3 0 Glycosyl transferase 4-like domain LRR_6 PF13516.6 AIN98469.1 - 5.5e-11 41.6 9.9 0.00042 20.1 0.0 7.9 9 0 0 9 9 9 3 Leucine Rich repeat cNMP_binding PF00027.29 AIN98470.1 - 4e-07 30.0 0.0 0.026 14.6 0.0 2.5 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain Cupin_2 PF07883.11 AIN98470.1 - 0.11 12.2 0.1 7.4 6.4 0.1 2.5 2 0 0 2 2 2 0 Cupin domain DUF3287 PF11690.8 AIN98471.1 - 0.084 12.6 1.4 0.15 11.8 1.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3287) DUF4699 PF15770.5 AIN98471.1 - 0.11 12.3 0.1 0.15 11.8 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4699) Atg14 PF10186.9 AIN98471.1 - 0.18 10.9 3.8 0.24 10.5 3.8 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 KELK PF15796.5 AIN98471.1 - 0.25 11.8 5.1 0.46 11.0 4.6 1.7 1 1 0 1 1 1 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase SPAM PF02090.15 AIN98471.1 - 0.29 10.9 7.0 1.5 8.6 7.0 2.0 1 1 0 1 1 1 0 Salmonella surface presentation of antigen gene type M protein DUF2205 PF10224.9 AIN98471.1 - 0.77 9.8 5.4 0.2 11.6 0.7 2.1 2 0 0 2 2 2 0 Short coiled-coil protein HAUS6_N PF14661.6 AIN98471.1 - 2.5 7.6 7.2 3.7 7.1 6.5 1.5 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 6 N-terminus PI-PLC-C1 PF16670.5 AIN98473.1 - 0.021 13.9 0.7 0.027 13.6 0.7 1.1 1 0 0 1 1 1 0 Phosphoinositide phospholipase C, Ca2+-dependent YjgF_endoribonc PF14588.6 AIN98474.1 - 4.2e-31 108.1 0.2 4.6e-31 108.0 0.2 1.0 1 0 0 1 1 1 1 YjgF/chorismate_mutase-like, putative endoribonuclease Ribonuc_L-PSP PF01042.21 AIN98474.1 - 1.5e-20 73.4 0.1 1.9e-20 73.1 0.1 1.1 1 0 0 1 1 1 1 Endoribonuclease L-PSP ABC_membrane PF00664.23 AIN98475.1 - 2.4e-55 188.1 34.9 6.4e-28 98.2 13.6 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 AIN98475.1 - 1.4e-21 77.4 0.0 2.6e-21 76.6 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_16 PF13191.6 AIN98475.1 - 0.00037 20.9 0.1 0.0014 19.0 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain AAA_21 PF13304.6 AIN98475.1 - 0.00054 19.9 0.0 0.0026 17.6 0.0 1.9 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 AIN98475.1 - 0.00074 19.0 0.1 0.092 12.2 0.1 2.3 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 AIN98475.1 - 0.00076 19.2 0.1 0.0018 18.0 0.1 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_25 PF13481.6 AIN98475.1 - 0.0011 18.5 0.0 0.0025 17.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 AIN98475.1 - 0.0012 17.9 0.0 0.003 16.7 0.0 1.6 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_22 PF13401.6 AIN98475.1 - 0.0029 17.9 0.0 0.0089 16.3 0.0 1.8 1 0 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 AIN98475.1 - 0.0036 17.1 0.0 0.0067 16.2 0.0 1.4 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase RsgA_GTPase PF03193.16 AIN98475.1 - 0.0048 16.8 0.0 0.01 15.8 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase FtsK_SpoIIIE PF01580.18 AIN98475.1 - 0.0053 16.1 0.0 0.011 15.1 0.0 1.4 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA_23 PF13476.6 AIN98475.1 - 0.0057 17.2 0.0 0.0091 16.5 0.0 1.2 1 0 0 1 1 1 1 AAA domain Tom5 PF10642.9 AIN98475.1 - 0.055 13.5 1.1 6.1 7.0 0.0 2.7 2 0 0 2 2 2 0 Mitochondrial import receptor subunit or translocase AAA_28 PF13521.6 AIN98475.1 - 0.067 13.4 0.0 0.13 12.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain ABC_ATPase PF09818.9 AIN98475.1 - 0.073 11.9 0.0 0.12 11.2 0.0 1.2 1 0 0 1 1 1 0 Predicted ATPase of the ABC class NACHT PF05729.12 AIN98475.1 - 0.076 12.9 0.1 0.17 11.8 0.1 1.6 1 0 0 1 1 1 0 NACHT domain AAA_30 PF13604.6 AIN98475.1 - 0.13 12.0 0.3 0.49 10.1 0.0 2.1 2 0 0 2 2 2 0 AAA domain DUF87 PF01935.17 AIN98475.1 - 0.14 12.2 0.4 0.26 11.3 0.4 1.3 1 0 0 1 1 1 0 Helicase HerA, central domain AAA_15 PF13175.6 AIN98475.1 - 0.18 11.4 0.0 0.26 11.0 0.0 1.1 1 0 0 1 1 1 0 AAA ATPase domain Yip1 PF04893.17 AIN98479.1 - 6.7e-17 61.7 17.9 9.1e-17 61.3 17.8 1.3 1 1 0 1 1 1 1 Yip1 domain ABC_membrane PF00664.23 AIN98480.1 - 1.3e-70 238.2 21.2 5e-38 131.3 11.8 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 AIN98480.1 - 4e-48 163.4 0.0 1.6e-24 86.9 0.0 2.5 2 0 0 2 2 2 2 ABC transporter AAA_29 PF13555.6 AIN98480.1 - 1.4e-08 34.3 0.6 0.001 18.8 0.1 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain SMC_N PF02463.19 AIN98480.1 - 2.2e-07 30.6 3.0 0.2 11.0 0.0 4.1 2 2 1 4 4 4 2 RecF/RecN/SMC N terminal domain FtsK_SpoIIIE PF01580.18 AIN98480.1 - 5.9e-06 25.8 1.2 0.024 14.0 0.2 2.6 2 0 0 2 2 2 2 FtsK/SpoIIIE family AAA_25 PF13481.6 AIN98480.1 - 1e-05 25.2 0.2 0.0017 18.0 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 AIN98480.1 - 1.5e-05 25.3 0.2 0.085 13.1 0.0 3.3 2 1 0 2 2 2 2 AAA domain AAA_21 PF13304.6 AIN98480.1 - 2.1e-05 24.5 0.0 0.085 12.6 0.0 3.6 4 0 0 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 AIN98480.1 - 6.1e-05 23.5 0.5 0.13 12.6 0.0 3.4 3 0 0 3 3 3 1 AAA ATPase domain RsgA_GTPase PF03193.16 AIN98480.1 - 7.4e-05 22.7 0.7 0.008 16.1 0.1 2.5 2 0 0 2 2 2 1 RsgA GTPase T2SSE PF00437.20 AIN98480.1 - 0.00011 21.4 0.0 0.11 11.6 0.0 2.4 2 0 0 2 2 2 2 Type II/IV secretion system protein MMR_HSR1 PF01926.23 AIN98480.1 - 0.00021 21.4 0.5 0.82 9.8 0.2 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_23 PF13476.6 AIN98480.1 - 0.00025 21.6 0.1 0.11 13.0 0.0 2.3 2 0 0 2 2 2 1 AAA domain DUF87 PF01935.17 AIN98480.1 - 0.00069 19.8 2.7 0.85 9.7 0.1 2.4 2 0 0 2 2 2 2 Helicase HerA, central domain CAP_GLY PF01302.25 AIN98480.1 - 0.0015 18.5 0.0 0.0046 16.9 0.0 1.8 1 0 0 1 1 1 1 CAP-Gly domain NACHT PF05729.12 AIN98480.1 - 0.0028 17.6 0.7 0.76 9.7 0.1 2.5 2 0 0 2 2 2 1 NACHT domain AAA_33 PF13671.6 AIN98480.1 - 0.0034 17.6 0.1 0.55 10.4 0.0 2.7 2 0 0 2 2 2 1 AAA domain Viral_helicase1 PF01443.18 AIN98480.1 - 0.0042 16.8 0.0 1.4 8.6 0.0 2.5 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase TrwB_AAD_bind PF10412.9 AIN98480.1 - 0.0046 15.9 0.4 1.1 8.1 0.0 2.3 2 0 0 2 2 2 1 Type IV secretion-system coupling protein DNA-binding domain AAA_30 PF13604.6 AIN98480.1 - 0.0049 16.6 0.7 0.54 9.9 0.1 2.6 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 AIN98480.1 - 0.0056 17.2 0.2 0.46 11.0 0.0 2.7 3 0 0 3 3 2 1 AAA domain AAA_7 PF12775.7 AIN98480.1 - 0.0096 15.5 0.4 1.5 8.3 0.1 2.4 2 0 0 2 2 2 1 P-loop containing dynein motor region cobW PF02492.19 AIN98480.1 - 0.011 15.3 0.1 4.5 6.8 0.0 2.6 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain RNA_helicase PF00910.22 AIN98480.1 - 0.013 15.8 0.1 1.1 9.6 0.0 2.6 2 0 0 2 2 2 0 RNA helicase Dynamin_N PF00350.23 AIN98480.1 - 0.019 15.1 0.6 1.7 8.7 0.0 2.3 2 0 0 2 2 2 0 Dynamin family Roc PF08477.13 AIN98480.1 - 0.036 14.3 0.5 13 6.0 0.3 2.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase ATP_bind_1 PF03029.17 AIN98480.1 - 0.038 13.8 2.5 2.5 7.8 0.2 2.5 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein Zeta_toxin PF06414.12 AIN98480.1 - 0.05 12.9 0.1 11 5.2 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin Ploopntkinase3 PF18751.1 AIN98480.1 - 0.084 12.8 0.1 1.7 8.5 0.0 2.4 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 AAA_14 PF13173.6 AIN98480.1 - 0.086 12.9 0.1 3.9 7.5 0.0 2.8 2 0 0 2 2 2 0 AAA domain Septin PF00735.18 AIN98480.1 - 0.28 10.4 0.4 5.4 6.2 0.0 2.1 2 0 0 2 2 2 0 Septin adh_short_C2 PF13561.6 AIN98481.1 - 2.1e-34 119.1 0.4 6.4e-32 111.0 0.4 2.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 AIN98481.1 - 3.1e-26 92.0 0.0 5.8e-24 84.6 0.0 2.1 1 1 0 1 1 1 1 short chain dehydrogenase zf-C3HC4 PF00097.25 AIN98482.1 - 7.9e-07 28.8 7.8 2.1e-06 27.5 7.8 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 AIN98482.1 - 1.1e-05 25.4 6.7 3.1e-05 23.9 6.7 1.9 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_4 PF15227.6 AIN98482.1 - 0.0011 19.0 8.6 0.0025 18.0 8.6 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.6 AIN98482.1 - 0.0057 16.5 8.7 0.0057 16.5 8.7 2.6 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 AIN98482.1 - 0.043 13.8 10.8 0.11 12.5 10.8 1.7 1 0 0 1 1 1 0 zinc-RING finger domain RNA_POL_M_15KD PF02150.16 AIN98482.1 - 0.091 12.7 3.3 0.19 11.6 3.3 1.5 1 0 0 1 1 1 0 RNA polymerases M/15 Kd subunit zf-RING_2 PF13639.6 AIN98482.1 - 0.34 11.3 10.8 0.24 11.8 8.3 2.1 2 0 0 2 2 2 0 Ring finger domain zf-RING_6 PF14835.6 AIN98482.1 - 0.47 10.4 6.7 2.1 8.3 6.7 2.0 1 1 0 1 1 1 0 zf-RING of BARD1-type protein TF_Zn_Ribbon PF08271.12 AIN98482.1 - 0.82 9.2 5.2 2 8.0 5.2 1.6 1 0 0 1 1 1 0 TFIIB zinc-binding zf-C3HC4_3 PF13920.6 AIN98482.1 - 1.3 8.9 8.7 3.5 7.6 8.7 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 AIN98482.1 - 2.1 8.3 7.1 7.4 6.5 6.8 2.1 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 zf-rbx1 PF12678.7 AIN98482.1 - 3.7 7.9 6.2 12 6.3 6.2 1.8 1 0 0 1 1 1 0 RING-H2 zinc finger domain Hus1 PF04005.12 AIN98483.1 - 1.1e-79 267.6 0.0 1.3e-79 267.4 0.0 1.0 1 0 0 1 1 1 1 Hus1-like protein tRNA-synt_1b PF00579.25 AIN98484.1 - 4.2e-17 62.4 0.0 9.2e-17 61.3 0.0 1.4 1 1 0 1 1 1 1 tRNA synthetases class I (W and Y) Opi1 PF08618.10 AIN98484.1 - 0.027 13.7 0.3 0.038 13.2 0.3 1.1 1 0 0 1 1 1 0 Transcription factor Opi1 DUF1799 PF08809.11 AIN98484.1 - 0.16 12.2 0.0 0.31 11.3 0.0 1.4 1 0 0 1 1 1 0 Phage related hypothetical protein (DUF1799) MSA-2c PF12238.8 AIN98484.1 - 0.22 11.5 1.9 1.1 9.2 1.9 1.9 2 0 0 2 2 2 0 Merozoite surface antigen 2c AAA_16 PF13191.6 AIN98485.1 - 0.0018 18.7 0.0 0.0043 17.5 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.14 AIN98485.1 - 0.0031 17.5 0.0 0.009 16.0 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 AIN98485.1 - 0.0073 16.6 0.0 0.016 15.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 AIN98485.1 - 0.0076 16.4 0.1 0.043 14.0 0.0 2.2 1 1 1 2 2 2 1 AAA domain ABC_tran PF00005.27 AIN98485.1 - 0.012 16.2 0.0 0.025 15.1 0.0 1.5 1 0 0 1 1 1 0 ABC transporter AAA_18 PF13238.6 AIN98485.1 - 0.017 15.7 0.1 0.059 13.9 0.0 2.0 2 0 0 2 2 2 0 AAA domain Mg_chelatase PF01078.21 AIN98485.1 - 0.018 14.4 1.1 0.17 11.2 0.0 2.7 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI tRNA_lig_kinase PF08303.11 AIN98485.1 - 0.021 14.9 0.0 0.15 12.2 0.0 2.0 1 1 0 1 1 1 0 tRNA ligase kinase domain RNA_helicase PF00910.22 AIN98485.1 - 0.037 14.4 0.0 0.078 13.4 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA PF00004.29 AIN98485.1 - 0.1 13.0 0.0 0.21 12.0 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ATP_bind_1 PF03029.17 AIN98485.1 - 0.11 12.3 0.0 0.18 11.5 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein AAA_15 PF13175.6 AIN98485.1 - 0.14 11.9 0.0 0.2 11.3 0.0 1.1 1 0 0 1 1 1 0 AAA ATPase domain NACHT PF05729.12 AIN98485.1 - 0.15 12.0 0.0 0.41 10.5 0.0 1.7 1 0 0 1 1 1 0 NACHT domain zf-RING_13 PF17977.1 AIN98486.1 - 0.027 14.6 0.1 0.066 13.4 0.1 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain V-ATPase_G PF03179.15 AIN98488.1 - 4.3e-22 78.6 13.5 4.7e-22 78.5 13.5 1.0 1 0 0 1 1 1 1 Vacuolar (H+)-ATPase G subunit V-ATPase_G_2 PF16999.5 AIN98488.1 - 0.13 12.7 14.3 0.16 12.4 14.3 1.1 1 0 0 1 1 1 0 Vacuolar (H+)-ATPase G subunit DUF4407 PF14362.6 AIN98488.1 - 6.7 6.0 11.6 8 5.7 11.6 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF883 PF05957.13 AIN98488.1 - 8.6 7.0 11.3 6.2 7.5 5.4 2.1 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) KptA_kDCL PF18176.1 AIN98491.1 - 3.9e-49 166.7 0.0 1.1e-48 165.2 0.0 1.9 1 0 0 1 1 1 1 KptA in kinetoplastid DICER domain PPL4 PF18188.1 AIN98491.1 - 7.3e-45 152.8 0.0 1.6e-44 151.7 0.0 1.6 1 0 0 1 1 1 1 Prim-pol 4 La_HTH_kDCL PF18177.1 AIN98491.1 - 8.4e-30 102.9 0.0 2.1e-29 101.6 0.0 1.7 1 0 0 1 1 1 1 La HTH in kinetoplastid DICER domain Ribonucleas_3_3 PF14622.6 AIN98491.1 - 0.0091 16.2 0.0 2.7 8.2 0.0 3.1 2 0 0 2 2 2 1 Ribonuclease-III-like Ribonuclease_3 PF00636.26 AIN98491.1 - 0.016 15.8 0.1 18 6.0 0.0 3.1 3 0 0 3 3 3 0 Ribonuclease III domain ADH_N PF08240.12 AIN98492.1 - 4.3e-27 94.1 12.1 4.4e-27 94.1 8.3 2.3 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 AIN98492.1 - 3.6e-22 78.7 0.0 6.7e-22 77.9 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 AIN98492.1 - 4.7e-07 29.5 0.3 6.8e-07 29.0 0.3 1.2 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus AlaDh_PNT_C PF01262.21 AIN98492.1 - 5.2e-07 29.2 0.1 8.3e-07 28.5 0.1 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.19 AIN98492.1 - 3.1e-06 26.7 0.1 5e-06 26.0 0.1 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ADH_zinc_N_2 PF13602.6 AIN98492.1 - 9.8e-06 26.7 0.0 1.8e-05 25.8 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase NAD_binding_2 PF03446.15 AIN98492.1 - 0.0002 21.6 0.3 0.00034 20.8 0.3 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase 3HCDH_N PF02737.18 AIN98492.1 - 0.011 15.7 0.2 0.018 14.9 0.2 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 AIN98492.1 - 0.028 14.5 0.0 0.059 13.4 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase ApbA PF02558.16 AIN98492.1 - 0.063 12.9 0.1 0.12 12.0 0.1 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA DUF364 PF04016.12 AIN98492.1 - 0.076 12.6 0.0 0.13 11.8 0.0 1.4 1 0 0 1 1 1 0 Putative heavy-metal chelation ABC_tran PF00005.27 AIN98494.1 - 4.3e-30 105.0 0.0 7.2e-30 104.3 0.0 1.4 1 0 0 1 1 1 1 ABC transporter ABC2_membrane PF01061.24 AIN98494.1 - 3.9e-23 82.0 19.3 3.9e-23 82.0 19.3 2.8 3 0 0 3 3 3 1 ABC-2 type transporter AAA_16 PF13191.6 AIN98494.1 - 7.3e-05 23.2 0.1 0.00023 21.6 0.1 1.8 1 0 0 1 1 1 1 AAA ATPase domain AAA_21 PF13304.6 AIN98494.1 - 0.00063 19.6 0.1 0.3 10.8 0.0 2.2 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 AIN98494.1 - 0.00069 19.3 0.0 0.0023 17.6 0.0 1.9 1 0 0 1 1 1 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 AIN98494.1 - 0.0013 18.7 0.2 0.0028 17.6 0.2 1.5 1 0 0 1 1 1 1 RsgA GTPase AAA_22 PF13401.6 AIN98494.1 - 0.0082 16.4 0.1 0.025 14.8 0.1 1.8 1 1 0 1 1 1 1 AAA domain AAA_23 PF13476.6 AIN98494.1 - 0.012 16.1 0.0 0.022 15.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 AIN98494.1 - 0.06 13.0 0.2 0.12 12.1 0.2 1.4 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 AIN98494.1 - 0.09 13.3 0.3 0.18 12.4 0.3 1.4 1 0 0 1 1 1 0 AAA domain Rad17 PF03215.15 AIN98494.1 - 0.098 12.6 0.0 0.23 11.4 0.0 1.5 1 0 0 1 1 1 0 Rad17 P-loop domain ABC2_membrane_3 PF12698.7 AIN98494.1 - 0.14 11.2 25.5 0.055 12.6 20.7 2.2 2 0 0 2 2 2 0 ABC-2 family transporter protein T2SSE PF00437.20 AIN98494.1 - 0.25 10.3 1.1 2.1 7.3 0.0 2.3 3 0 0 3 3 3 0 Type II/IV secretion system protein AAA_28 PF13521.6 AIN98494.1 - 0.38 11.0 3.5 0.31 11.2 0.7 2.1 2 0 0 2 2 2 0 AAA domain Cmc1 PF08583.10 AIN98495.1 - 0.053 13.6 1.1 0.11 12.5 1.1 1.5 1 0 0 1 1 1 0 Cytochrome c oxidase biogenesis protein Cmc1 like Hormone_5 PF00184.17 AIN98497.1 - 0.0019 19.0 1.6 0.0019 19.0 1.6 1.6 1 1 0 1 1 1 1 Neurohypophysial hormones, C-terminal Domain Aldose_epim PF01263.20 AIN98498.1 - 1.6e-53 182.0 0.0 3.8e-53 180.8 0.0 1.5 1 1 0 1 1 1 1 Aldose 1-epimerase FtsX PF02687.21 AIN98500.1 - 1e-13 51.5 21.3 5.9e-10 39.5 10.2 7.1 7 1 0 7 7 7 2 FtsX-like permease family Transketolase_C PF02780.20 AIN98500.1 - 0.055 13.3 0.0 0.13 12.2 0.0 1.6 1 0 0 1 1 1 0 Transketolase, C-terminal domain CHAP PF05257.16 AIN98501.1 - 8.4e-10 39.1 0.7 1.5e-08 35.1 0.7 2.4 1 1 0 1 1 1 1 CHAP domain AMPKBI PF04739.15 AIN98504.1 - 5.6e-14 52.2 1.5 5.6e-14 52.2 1.5 1.8 2 0 0 2 2 2 1 5'-AMP-activated protein kinase beta subunit, interaction domain AMPK1_CBM PF16561.5 AIN98504.1 - 3e-08 33.8 0.0 5.8e-08 32.8 0.0 1.4 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase SET PF00856.28 AIN98507.1 - 2.9e-12 47.3 0.0 1.1e-11 45.4 0.0 1.8 1 1 0 1 1 1 1 SET domain FtsJ PF01728.19 AIN98508.1 - 1.2e-47 162.2 0.0 1.5e-47 162.0 0.0 1.1 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_23 PF13489.6 AIN98508.1 - 0.0022 17.8 0.0 0.0046 16.8 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 AIN98508.1 - 0.16 12.7 0.3 1.1 10.1 0.1 2.3 1 1 0 2 2 2 0 Methyltransferase domain AMP-binding PF00501.28 AIN98509.1 - 1.2e-86 291.0 0.0 1.4e-86 290.7 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 AIN98509.1 - 3.4e-17 63.2 1.9 6.4e-17 62.3 1.9 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain ACAS_N PF16177.5 AIN98509.1 - 8.3e-17 60.9 3.9 2e-16 59.7 3.9 1.6 1 0 0 1 1 1 1 Acetyl-coenzyme A synthetase N-terminus EF-hand_8 PF13833.6 AIN98510.1 - 4.9e-06 26.3 0.4 0.068 13.0 0.0 3.3 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_6 PF13405.6 AIN98510.1 - 7.9e-06 25.4 0.1 0.4 10.7 0.0 3.3 3 1 0 3 3 3 2 EF-hand domain EF-hand_7 PF13499.6 AIN98510.1 - 4.8e-05 23.7 0.0 0.00073 19.9 0.0 2.5 2 1 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.32 AIN98510.1 - 0.00087 18.7 0.0 0.11 12.1 0.0 2.7 2 0 0 2 2 2 1 EF hand EF-hand_5 PF13202.6 AIN98510.1 - 0.15 11.7 0.1 17 5.1 0.0 2.5 2 0 0 2 2 2 0 EF hand XRN_N PF03159.18 AIN98511.1 - 2.7e-59 200.6 0.0 4.1e-59 199.9 0.0 1.3 1 0 0 1 1 1 1 XRN 5'-3' exonuclease N-terminus XRN_M PF17846.1 AIN98511.1 - 9.3e-07 28.1 13.2 0.00026 20.1 0.0 4.0 4 0 0 4 4 4 3 Xrn1 helical domain DUF4587 PF15248.6 AIN98511.1 - 1.8 9.4 5.3 22 5.9 0.0 3.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4587) DUF4349 PF14257.6 AIN98512.1 - 0.45 9.9 3.7 1.1 8.6 3.7 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4349) GFO_IDH_MocA PF01408.22 AIN98513.1 - 3.9e-09 37.4 0.2 1.3e-08 35.7 0.0 2.0 2 0 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold F420_oxidored PF03807.17 AIN98513.1 - 0.00046 20.7 0.2 0.0015 19.1 0.0 2.1 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent CoA_binding_3 PF13727.6 AIN98513.1 - 0.016 15.2 0.0 0.038 14.0 0.0 1.6 1 0 0 1 1 1 0 CoA-binding domain HEPN_DZIP3 PF18738.1 AIN98513.1 - 0.092 12.5 0.0 0.14 11.9 0.0 1.3 1 0 0 1 1 1 0 DZIP3/ hRUL138-like HEPN CAF1 PF04857.20 AIN98516.1 - 2e-70 237.5 0.0 2.5e-70 237.2 0.0 1.1 1 0 0 1 1 1 1 CAF1 family ribonuclease MEDS PF14417.6 AIN98516.1 - 0.12 12.2 0.7 0.29 11.0 0.7 1.7 1 0 0 1 1 1 0 MEDS: MEthanogen/methylotroph, DcmR Sensory domain Kelch_4 PF13418.6 AIN98517.1 - 8.1e-11 41.8 12.5 0.0022 18.0 0.0 5.9 5 1 0 5 5 5 4 Galactose oxidase, central domain Kelch_5 PF13854.6 AIN98517.1 - 1.4e-10 40.9 13.4 0.0015 18.5 0.6 5.4 5 0 0 5 5 5 3 Kelch motif Kelch_3 PF13415.6 AIN98517.1 - 1.5e-09 37.9 12.5 1e-06 28.8 0.4 5.6 5 0 0 5 5 5 2 Galactose oxidase, central domain Kelch_1 PF01344.25 AIN98517.1 - 1.2e-08 34.4 13.5 0.00056 19.4 0.1 5.6 5 1 0 5 5 5 2 Kelch motif Kelch_6 PF13964.6 AIN98517.1 - 1.4e-06 28.3 9.1 0.86 10.0 0.1 6.0 6 0 0 6 6 6 3 Kelch motif Kelch_2 PF07646.15 AIN98517.1 - 7.3e-05 22.6 7.9 2.4 8.3 0.1 5.8 5 1 0 5 5 5 2 Kelch motif tRNA_bind PF01588.20 AIN98518.1 - 1.8e-12 47.2 0.4 2.5e-12 46.7 0.4 1.2 1 0 0 1 1 1 1 Putative tRNA binding domain zf-RanBP PF00641.18 AIN98518.1 - 0.00067 18.9 4.4 0.0012 18.1 4.4 1.4 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others zf-ribbon_3 PF13248.6 AIN98518.1 - 0.037 13.4 1.8 0.088 12.2 1.8 1.6 1 0 0 1 1 1 0 zinc-ribbon domain DZR PF12773.7 AIN98518.1 - 0.05 13.6 2.8 0.088 12.8 2.8 1.5 1 0 0 1 1 1 0 Double zinc ribbon PvlArgDC PF01862.16 AIN98518.1 - 0.1 12.4 0.2 0.2 11.5 0.2 1.5 1 1 0 1 1 1 0 Pyruvoyl-dependent arginine decarboxylase (PvlArgDC) zinc_ribbon_2 PF13240.6 AIN98518.1 - 0.21 11.4 2.5 0.42 10.4 2.5 1.5 1 0 0 1 1 1 0 zinc-ribbon domain Lactamase_B PF00753.27 AIN98519.1 - 1.6e-08 34.8 0.3 2.1e-06 27.9 0.2 2.2 2 0 0 2 2 2 2 Metallo-beta-lactamase superfamily PAP2 PF01569.21 AIN98520.1 - 5.8e-07 29.4 5.8 5.8e-07 29.4 5.8 2.6 1 1 2 3 3 3 1 PAP2 superfamily DUF212 PF02681.14 AIN98520.1 - 1.1 9.5 7.9 2.4 8.3 1.8 2.9 2 1 0 2 2 2 0 Divergent PAP2 family ThiF PF00899.21 AIN98521.1 - 7.7e-89 297.2 0.2 1e-63 215.0 0.0 2.6 2 1 0 2 2 2 2 ThiF family UBA_e1_thiolCys PF10585.9 AIN98521.1 - 2.5e-64 217.6 0.4 3.8e-64 217.0 0.4 1.3 1 0 0 1 1 1 1 Ubiquitin-activating enzyme active site E1_UFD PF09358.10 AIN98521.1 - 2.6e-11 44.1 0.0 5.1e-11 43.1 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin fold domain E1_FCCH PF16190.5 AIN98521.1 - 0.00012 22.2 0.0 0.0003 20.9 0.0 1.7 1 0 0 1 1 1 1 Ubiquitin-activating enzyme E1 FCCH domain E1_4HB PF16191.5 AIN98521.1 - 0.00081 19.5 0.0 0.0023 18.1 0.0 1.8 1 0 0 1 1 1 1 Ubiquitin-activating enzyme E1 four-helix bundle Shikimate_DH PF01488.20 AIN98521.1 - 0.0009 19.3 0.4 0.6 10.2 0.0 2.5 2 0 0 2 2 2 2 Shikimate / quinate 5-dehydrogenase Kinesin PF00225.23 AIN98522.1 - 2.9e-86 289.4 0.0 7.5e-86 288.1 0.0 1.7 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 AIN98522.1 - 1.5e-15 57.4 0.0 7.2e-15 55.2 0.0 2.2 1 1 0 1 1 1 1 Microtubule binding MYCBPAP PF14646.6 AIN98523.1 - 1.8e-10 40.4 5.5 6.1e-09 35.3 0.2 2.7 2 1 0 2 2 2 2 MYCBP-associated protein family TMEM192 PF14802.6 AIN98526.1 - 0.055 12.6 1.0 0.08 12.0 1.0 1.1 1 0 0 1 1 1 0 TMEM192 family BING4CT PF08149.11 AIN98528.1 - 4e-29 100.2 0.2 2.5e-28 97.7 0.0 2.4 3 0 0 3 3 3 1 BING4CT (NUC141) domain WD40 PF00400.32 AIN98528.1 - 6.1e-07 30.0 0.9 5.9e-06 26.9 0.0 2.9 3 0 0 3 3 3 1 WD domain, G-beta repeat Sec10 PF07393.11 AIN98529.1 - 1.5e-27 96.4 6.3 4.9e-25 88.1 0.0 3.1 3 0 0 3 3 3 2 Exocyst complex component Sec10 Peptidase_S46 PF10459.9 AIN98529.1 - 0.056 12.1 0.4 0.099 11.3 0.4 1.3 1 0 0 1 1 1 0 Peptidase S46 Spc7 PF08317.11 AIN98529.1 - 0.35 9.7 2.7 0.71 8.7 2.7 1.4 1 0 0 1 1 1 0 Spc7 kinetochore protein PepSY_TM_like_2 PF16357.5 AIN98530.1 - 0.072 13.1 0.2 0.16 12.0 0.2 1.6 1 0 0 1 1 1 0 Putative PepSY_TM-like tRNA_anti-like PF12869.7 AIN98530.1 - 0.24 11.0 2.7 1.4 8.5 1.1 2.6 2 0 0 2 2 2 0 tRNA_anti-like DUF3302 PF11742.8 AIN98530.1 - 0.28 11.4 0.0 0.28 11.4 0.0 3.1 4 0 0 4 4 4 0 Protein of unknown function (DUF3302) Shisa PF13908.6 AIN98530.1 - 0.83 9.9 4.9 0.36 11.0 0.2 2.7 4 0 0 4 4 4 0 Wnt and FGF inhibitory regulator UPF0242 PF06785.11 AIN98530.1 - 1 9.4 6.4 2.4 8.2 6.4 1.5 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus RR_TM4-6 PF06459.12 AIN98530.1 - 1.2 8.9 7.4 2 8.2 7.4 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 IFT20 PF14931.6 AIN98530.1 - 1.8 8.8 12.7 0.52 10.5 9.3 1.8 2 0 0 2 2 2 0 Intraflagellar transport complex B, subunit 20 DUF2517 PF10725.9 AIN98530.1 - 2.4 8.0 5.5 0.31 10.8 0.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2517) MRP-S31 PF15433.6 AIN98530.1 - 6.4 6.3 9.3 9.8 5.7 9.3 1.2 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S31 DIM1 PF02966.16 AIN98531.1 - 1.4e-29 102.5 0.2 3.1e-25 88.5 0.1 2.2 2 0 0 2 2 2 2 Mitosis protein DIM1 DUF726 PF05277.12 AIN98532.1 - 2.5 7.0 7.1 5.2 5.9 0.3 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF726) PriCT_2 PF08707.11 AIN98533.1 - 1.7e-16 60.3 1.8 3.5e-16 59.3 1.8 1.6 1 0 0 1 1 1 1 Primase C terminal 2 (PriCT-2) PPL5 PF18168.1 AIN98533.1 - 3.6e-07 29.8 1.3 0.00014 21.3 0.0 2.9 3 0 0 3 3 3 2 Prim-pol family 5 DNA_primase_S PF01896.19 AIN98533.1 - 0.11 12.6 0.0 0.21 11.6 0.0 1.5 1 0 0 1 1 1 0 DNA primase small subunit DUF5302 PF17227.2 AIN98533.1 - 5.2 8.1 7.1 14 6.8 0.7 2.6 1 1 1 2 2 2 0 Family of unknown function (DUF5302) Thiolase_N PF00108.23 AIN98534.1 - 2.5e-15 56.6 4.7 6.8e-15 55.1 2.5 2.5 2 1 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 AIN98534.1 - 1.4e-12 47.4 1.2 2.2e-11 43.5 0.1 2.7 2 1 1 3 3 3 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 AIN98534.1 - 8.4e-09 35.4 1.0 1.2e-07 31.6 0.4 2.5 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.10 AIN98534.1 - 0.0066 16.3 1.6 0.69 9.8 1.5 2.7 3 0 0 3 3 3 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Ketoacyl-synt_C PF02801.22 AIN98534.1 - 0.98 9.4 4.9 9.4 6.3 0.0 3.5 3 1 0 4 4 4 0 Beta-ketoacyl synthase, C-terminal domain COX17 PF05051.13 AIN98535.1 - 3.9e-06 27.1 0.6 5.9e-06 26.5 0.6 1.2 1 0 0 1 1 1 1 Cytochrome C oxidase copper chaperone (COX17) AMP-binding PF00501.28 AIN98536.1 - 1.1e-84 284.5 0.0 1.3e-84 284.2 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme ACAS_N PF16177.5 AIN98536.1 - 8e-17 60.9 3.8 2e-16 59.7 3.8 1.7 1 0 0 1 1 1 1 Acetyl-coenzyme A synthetase N-terminus AMP-binding_C PF13193.6 AIN98536.1 - 1.1e-16 61.5 0.3 2.3e-16 60.5 0.3 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain RRM_1 PF00076.22 AIN98537.1 - 1.5e-11 43.9 0.0 2.4e-11 43.3 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.22 AIN98538.1 - 2e-13 49.9 0.0 3.5e-13 49.2 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) MMR_HSR1 PF01926.23 AIN98539.1 - 1.2e-10 41.5 0.0 4e-10 39.8 0.0 1.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 AIN98539.1 - 2e-05 24.7 0.1 9.7e-05 22.5 0.1 2.0 1 1 1 2 2 2 1 Dynamin family RsgA_GTPase PF03193.16 AIN98539.1 - 5.8e-05 23.1 0.0 0.0035 17.3 0.0 2.3 2 0 0 2 2 2 1 RsgA GTPase AAA_29 PF13555.6 AIN98539.1 - 0.00052 19.7 0.0 0.029 14.1 0.0 2.4 2 0 0 2 2 2 1 P-loop containing region of AAA domain Methyltransf_14 PF08484.11 AIN98539.1 - 0.076 12.8 0.1 0.14 12.0 0.1 1.3 1 0 0 1 1 1 0 C-methyltransferase C-terminal domain ABC_tran PF00005.27 AIN98539.1 - 0.092 13.3 0.0 0.23 12.0 0.0 1.6 1 0 0 1 1 1 0 ABC transporter FeoB_N PF02421.18 AIN98539.1 - 0.11 12.0 0.0 0.2 11.1 0.0 1.4 1 0 0 1 1 1 0 Ferrous iron transport protein B DUF1738 PF08401.11 AIN98540.1 - 1e-05 25.7 0.0 0.00041 20.5 0.0 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF1738) DUF1738 PF08401.11 AIN98541.1 - 0.00027 21.1 0.4 0.27 11.3 0.3 3.0 2 1 1 3 3 3 2 Domain of unknown function (DUF1738) DUF676 PF05057.14 AIN98543.1 - 5.4e-12 45.7 0.0 1.1e-09 38.1 0.0 2.7 2 1 0 2 2 2 2 Putative serine esterase (DUF676) Corona_5a PF06336.11 AIN98543.1 - 1.8 8.6 3.5 1.5 8.8 1.3 2.0 2 0 0 2 2 2 0 Coronavirus 5a protein FAD-oxidase_C PF02913.19 AIN98546.1 - 9.2e-47 159.8 0.0 1.3e-46 159.2 0.0 1.2 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 AIN98546.1 - 1.2e-29 102.8 1.9 1.9e-29 102.2 1.1 1.8 2 0 0 2 2 2 1 FAD binding domain SET PF00856.28 AIN98547.1 - 8.2e-10 39.3 0.0 1.6e-09 38.4 0.0 1.9 1 1 0 1 1 1 1 SET domain zinc_ribbon_5 PF13719.6 AIN98547.1 - 0.11 12.2 0.4 0.11 12.2 0.4 2.0 2 0 0 2 2 2 0 zinc-ribbon domain zf-MYND PF01753.18 AIN98547.1 - 0.99 9.6 17.0 0.063 13.4 10.2 2.5 2 1 0 2 2 2 0 MYND finger Na_H_Exchanger PF00999.21 AIN98548.1 - 1.8e-48 165.3 43.5 2.6e-48 164.7 43.5 1.2 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family TetR_C_23 PF17931.1 AIN98548.1 - 0.037 14.1 0.1 0.27 11.4 0.1 2.2 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain Phostensin_N PF13916.6 AIN98548.1 - 0.26 11.7 1.3 1.9 8.9 0.9 2.3 2 0 0 2 2 2 0 PP1-regulatory protein, Phostensin N-terminal TPR_12 PF13424.6 AIN98552.1 - 0.00016 21.9 0.2 0.47 10.8 0.0 3.1 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.6 AIN98552.1 - 0.012 16.3 1.5 0.44 11.5 0.0 4.1 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF4919 PF16266.5 AIN98552.1 - 0.062 13.2 0.0 0.15 12.0 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4919) TPR_8 PF13181.6 AIN98552.1 - 0.1 12.9 0.1 2.9 8.3 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_10 PF13374.6 AIN98552.1 - 1.7 8.7 5.5 1.3 9.0 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat ADH_zinc_N_2 PF13602.6 AIN98553.1 - 1.5e-19 71.4 0.0 4.3e-19 69.9 0.0 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 AIN98553.1 - 1.6e-08 34.4 0.3 6.1e-08 32.5 0.1 2.1 2 1 1 3 3 3 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 AIN98553.1 - 7.9e-06 25.9 0.1 7.5e-05 22.7 0.0 2.4 2 1 0 2 2 2 1 Zinc-binding dehydrogenase TMEM187 PF15100.6 AIN98553.1 - 0.069 12.7 0.1 0.11 12.1 0.1 1.2 1 0 0 1 1 1 0 TMEM187 protein family Glyco_hydro_32N PF00251.20 AIN98554.1 - 3.9e-86 289.4 0.2 6e-86 288.7 0.2 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 N-terminal domain Glyco_hydro_32C PF08244.12 AIN98554.1 - 4.5e-20 72.2 0.0 6.4e-20 71.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 C terminal Glyco_hydro_43 PF04616.14 AIN98554.1 - 2.2e-06 27.2 0.3 3.3e-06 26.6 0.3 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 Methyltransf_28 PF02636.17 AIN98555.1 - 6.3e-60 203.0 0.0 8.7e-60 202.6 0.0 1.2 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase NIF PF03031.18 AIN98556.1 - 0.011 15.5 0.1 0.035 13.9 0.0 1.8 2 0 0 2 2 2 0 NLI interacting factor-like phosphatase HAD PF12710.7 AIN98556.1 - 0.06 13.7 1.1 0.48 10.8 0.0 2.8 3 0 0 3 3 3 0 haloacid dehalogenase-like hydrolase Peptidase_M17 PF00883.21 AIN98558.1 - 2.1e-103 345.9 0.0 3.2e-103 345.3 0.0 1.3 1 0 0 1 1 1 1 Cytosol aminopeptidase family, catalytic domain CHB_HEX_C_1 PF13290.6 AIN98559.1 - 3.4e-06 27.0 0.3 0.00041 20.3 0.2 2.9 3 0 0 3 3 3 1 Chitobiase/beta-hexosaminidase C-terminal domain Fn3_assoc PF13287.6 AIN98559.1 - 3.2e-05 24.0 0.1 0.27 11.4 0.0 4.1 4 0 0 4 4 4 2 Fn3 associated DUF4381 PF14316.6 AIN98559.1 - 0.11 12.7 0.2 0.23 11.7 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) Imm3 PF14425.6 AIN98561.1 - 0.12 12.4 0.3 0.54 10.3 0.2 2.0 1 1 1 2 2 2 0 Immunity protein Imm3 Mucin2_WxxW PF13330.6 AIN98561.1 - 1.9 9.4 5.3 26 5.7 0.4 3.1 2 1 0 2 2 2 0 Mucin-2 protein WxxW repeating region Integrin_B_tail PF07965.12 AIN98561.1 - 3.8 8.1 7.6 0.19 12.2 1.2 2.1 3 0 0 3 3 3 0 Integrin beta tail domain PspA_IM30 PF04012.12 AIN98563.1 - 0.0065 16.1 0.3 0.0065 16.1 0.3 2.3 2 1 0 2 2 2 1 PspA/IM30 family OmpH PF03938.14 AIN98563.1 - 0.034 14.5 7.8 0.1 12.9 5.6 2.0 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) TMPIT PF07851.13 AIN98563.1 - 1.4 8.1 8.5 0.21 10.8 4.1 1.7 2 0 0 2 2 2 0 TMPIT-like protein Seryl_tRNA_N PF02403.22 AIN98563.1 - 6.5 7.0 11.5 4.1 7.7 5.1 2.2 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Spore_YhaL PF14147.6 AIN98565.1 - 0.12 12.1 0.5 0.12 12.1 0.5 2.4 3 0 0 3 3 3 0 Sporulation protein YhaL ATP-synt_B PF00430.18 AIN98565.1 - 8.1 6.5 14.1 1.6 8.8 3.7 2.0 1 1 1 2 2 2 0 ATP synthase B/B' CF(0) KIAA1430 PF13879.6 AIN98567.1 - 0.0027 18.4 0.5 0.0061 17.3 0.5 1.6 1 0 0 1 1 1 1 KIAA1430 homologue Bd3614-deam PF14439.6 AIN98568.1 - 0.094 12.8 0.1 0.23 11.5 0.1 1.6 1 0 0 1 1 1 0 Bd3614-like deaminase 5-FTHF_cyc-lig PF01812.20 AIN98569.1 - 1.4e-13 51.1 2.6 4.8e-10 39.6 0.0 3.3 4 0 0 4 4 4 2 5-formyltetrahydrofolate cyclo-ligase family HIT PF01230.23 AIN98570.1 - 9.1e-12 45.6 0.1 3e-11 43.9 0.1 1.9 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.8 AIN98570.1 - 6.9e-06 26.5 0.1 4e-05 24.1 0.1 2.1 1 1 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding UPF0730 PF15827.5 AIN98570.1 - 0.012 15.3 0.3 0.16 11.7 0.1 2.5 2 0 0 2 2 2 0 UPF0730 unknown protein family Peptidase_C2 PF00648.21 AIN98570.1 - 0.057 12.4 0.2 0.085 11.9 0.2 1.2 1 0 0 1 1 1 0 Calpain family cysteine protease VSG_B PF13206.6 AIN98570.1 - 0.13 11.5 2.4 0.21 10.8 2.4 1.3 1 0 0 1 1 1 0 Trypanosomal VSG domain LRR_4 PF12799.7 AIN98573.1 - 3e-15 56.1 5.1 0.0088 16.4 0.0 7.3 4 2 4 9 9 9 6 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 AIN98573.1 - 0.00067 19.4 13.6 1.8 8.4 0.7 6.9 5 1 3 8 8 8 2 Leucine rich repeat LRR_5 PF13306.6 AIN98573.1 - 0.001 19.1 1.2 1 9.3 0.0 3.4 2 1 1 3 3 3 2 BspA type Leucine rich repeat region (6 copies) LRR_1 PF00560.33 AIN98573.1 - 0.014 15.9 8.4 35 5.5 0.1 6.8 7 1 0 7 7 7 0 Leucine Rich Repeat Stealth_CR2 PF11380.8 AIN98574.1 - 4.3e-25 88.0 0.3 6.4e-20 71.3 0.0 2.6 2 0 0 2 2 2 2 Stealth protein CR2, conserved region 2 Stealth_CR3 PF17102.5 AIN98574.1 - 1.1e-11 44.4 0.3 3.1e-11 43.0 0.3 1.8 1 0 0 1 1 1 1 Stealth protein CR3, conserved region 3 DUF2270 PF10028.9 AIN98574.1 - 0.048 13.2 0.3 0.088 12.4 0.3 1.3 1 0 0 1 1 1 0 Predicted integral membrane protein (DUF2270) CH PF00307.31 AIN98575.1 - 0.0022 18.1 0.0 0.0048 17.1 0.0 1.5 1 1 0 1 1 1 1 Calponin homology (CH) domain Mucin15 PF15672.5 AIN98575.1 - 0.051 13.1 0.0 0.086 12.3 0.0 1.3 1 0 0 1 1 1 0 Cell-membrane associated Mucin15 Pox_A_type_inc PF04508.12 AIN98576.1 - 1.4e-05 24.7 4.8 0.25 11.3 0.0 4.4 3 0 0 3 3 3 2 Viral A-type inclusion protein repeat Cnn_1N PF07989.11 AIN98576.1 - 0.0002 21.4 1.0 0.0002 21.4 1.0 4.4 5 0 0 5 5 5 1 Centrosomin N-terminal motif 1 DHR10 PF18595.1 AIN98576.1 - 0.00095 19.2 6.2 0.00095 19.2 6.2 5.1 5 1 0 5 5 4 1 Designed helical repeat protein 10 domain CENP-F_leu_zip PF10473.9 AIN98576.1 - 0.0052 16.8 4.1 0.0052 16.8 4.1 5.4 4 1 1 5 5 5 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF16 PF01519.16 AIN98576.1 - 0.013 16.0 4.2 0.013 16.0 4.2 3.9 3 1 0 3 3 3 0 Protein of unknown function DUF16 DivIC PF04977.15 AIN98576.1 - 0.26 11.1 31.0 0.26 11.1 1.3 5.8 5 1 1 6 6 6 0 Septum formation initiator PKcGMP_CC PF16808.5 AIN98576.1 - 0.47 10.3 8.3 0.4 10.6 3.0 3.4 2 1 0 2 2 2 0 Coiled-coil N-terminus of cGMP-dependent protein kinase DUF5082 PF16888.5 AIN98576.1 - 1.2 9.4 12.5 23 5.3 0.5 4.1 2 1 1 3 3 3 0 Domain of unknown function (DUF5082) Bacillus_HBL PF05791.11 AIN98576.1 - 5.6 6.8 5.2 1.3 8.8 1.1 2.0 2 0 0 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) Syntaxin_2 PF14523.6 AIN98576.1 - 6.7 7.2 7.9 0.52 10.7 0.5 2.8 3 0 0 3 3 3 0 Syntaxin-like protein DUF3450 PF11932.8 AIN98576.1 - 9 5.5 25.9 1 8.6 2.3 4.5 4 0 0 4 4 4 0 Protein of unknown function (DUF3450) Sipho_Gp157 PF05565.11 AIN98576.1 - 9 6.3 9.9 1.5 8.8 0.5 3.0 2 1 2 4 4 4 0 Siphovirus Gp157 JUPITER PF17054.5 AIN98578.1 - 0.019 14.4 0.0 0.044 13.3 0.0 1.5 1 0 0 1 1 1 0 Microtubule-Associated protein Jupiter Ly49 PF08391.10 AIN98578.1 - 1.4 9.3 5.7 0.71 10.2 1.1 2.7 1 1 0 2 2 2 0 Ly49-like protein, N-terminal region DUF948 PF06103.11 AIN98578.1 - 1.5 9.2 11.2 6.6 7.1 0.1 4.6 4 1 0 5 5 5 0 Bacterial protein of unknown function (DUF948) DUF4061 PF13270.6 AIN98578.1 - 1.5 9.2 7.9 3.7 7.9 0.6 3.1 2 1 1 3 3 3 0 Domain of unknown function (DUF4061) WD40_4 PF16300.5 AIN98580.1 - 1e-11 44.5 0.0 2.1e-11 43.5 0.0 1.6 1 0 0 1 1 1 1 Type of WD40 repeat DUF1899 PF08953.11 AIN98580.1 - 7.4e-11 41.8 0.0 1.3e-10 40.9 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1899) WD40 PF00400.32 AIN98580.1 - 0.00046 20.9 5.5 0.17 12.8 0.1 4.6 5 0 0 5 5 5 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 AIN98580.1 - 0.017 15.4 0.1 0.16 12.3 0.1 2.3 1 1 1 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain Ribosomal_S9 PF00380.19 AIN98581.1 - 0.00028 21.4 0.0 0.00054 20.5 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein S9/S16 TMEM234 PF10639.9 AIN98582.1 - 1.7e-36 124.8 1.2 2e-36 124.6 1.2 1.0 1 0 0 1 1 1 1 Putative transmembrane family 234 EamA PF00892.20 AIN98582.1 - 9.6e-09 35.5 6.1 7.4e-05 22.9 3.0 2.1 2 0 0 2 2 2 2 EamA-like transporter family Herpes_LMP1 PF05297.11 AIN98582.1 - 0.0031 16.8 0.7 0.0031 16.8 0.7 1.4 2 0 0 2 2 2 1 Herpesvirus latent membrane protein 1 (LMP1) His_Phos_2 PF00328.22 AIN98583.1 - 5.3e-11 42.5 0.1 5.3e-08 32.6 0.0 2.7 2 1 0 2 2 2 2 Histidine phosphatase superfamily (branch 2) Cytomega_UL20A PF05984.12 AIN98583.1 - 0.08 13.3 0.1 0.15 12.4 0.1 1.4 1 0 0 1 1 1 0 Cytomegalovirus UL20A protein Methyltransf_5 PF01795.19 AIN98584.1 - 8e-28 97.8 0.0 1.1e-27 97.4 0.0 1.1 1 0 0 1 1 1 1 MraW methylase family Methyltransf_31 PF13847.6 AIN98584.1 - 7.9e-06 25.7 0.0 0.00026 20.8 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 AIN98584.1 - 9.4e-05 23.0 0.0 0.0017 19.0 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 AIN98584.1 - 0.014 16.0 0.0 0.38 11.4 0.0 2.5 2 0 0 2 2 2 0 Methyltransferase domain MTS PF05175.14 AIN98584.1 - 0.11 12.0 0.0 0.27 10.8 0.0 1.6 2 0 0 2 2 2 0 Methyltransferase small domain SIR2 PF02146.17 AIN98585.1 - 3.6e-35 121.5 0.1 7.2e-34 117.2 0.1 2.1 1 1 0 1 1 1 1 Sir2 family Cpn60_TCP1 PF00118.24 AIN98586.1 - 2.4e-159 531.1 4.1 2.9e-159 530.9 4.1 1.1 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Tipalpha PF16753.5 AIN98586.1 - 0.045 13.6 0.1 0.27 11.0 0.0 2.2 2 0 0 2 2 2 0 TNF-alpha-Inducing protein of Helicobacter PPR_1 PF12854.7 AIN98588.1 - 9.3e-06 25.3 0.0 2.1e-05 24.1 0.0 1.7 2 0 0 2 2 2 1 PPR repeat PPR_3 PF13812.6 AIN98588.1 - 2.2e-05 24.4 0.0 5.3e-05 23.2 0.0 1.6 1 0 0 1 1 1 1 Pentatricopeptide repeat domain PPR_2 PF13041.6 AIN98588.1 - 0.00029 21.0 0.0 0.0013 18.9 0.0 2.1 2 0 0 2 2 2 1 PPR repeat family PPR PF01535.20 AIN98588.1 - 0.0046 17.1 0.5 0.014 15.6 0.1 2.1 2 0 0 2 2 2 1 PPR repeat SAP130_C PF16014.5 AIN98588.1 - 0.035 13.2 4.4 0.068 12.3 4.3 1.5 2 0 0 2 2 2 0 Histone deacetylase complex subunit SAP130 C-terminus C2-C2_1 PF11618.8 AIN98589.1 - 1.8e-28 99.4 6.6 2e-28 99.3 0.4 3.4 3 1 1 4 4 4 1 First C2 domain of RPGR-interacting protein 1 Macoilin PF09726.9 AIN98589.1 - 0.0083 14.7 1.1 0.0083 14.7 1.1 3.5 3 1 1 4 4 4 1 Macoilin family KNOX2 PF03791.13 AIN98589.1 - 0.027 14.0 0.2 0.083 12.4 0.2 1.8 1 0 0 1 1 1 0 KNOX2 domain GAS PF13851.6 AIN98589.1 - 1.7 8.0 36.0 0.24 10.7 8.3 3.6 3 1 0 4 4 4 0 Growth-arrest specific micro-tubule binding RICTOR_M PF14666.6 AIN98590.1 - 6e-22 77.4 0.0 2.4e-20 72.2 0.0 3.3 2 1 1 3 3 3 1 Rapamycin-insensitive companion of mTOR, middle domain RICTOR_N PF14664.6 AIN98590.1 - 3.2e-16 59.3 0.3 2.7e-13 49.7 0.0 2.7 3 0 0 3 3 3 2 Rapamycin-insensitive companion of mTOR, N-term RasGEF_N_2 PF14663.6 AIN98590.1 - 4.5e-12 46.3 2.7 4.9e-12 46.2 0.5 2.3 2 0 0 2 2 2 1 Rapamycin-insensitive companion of mTOR RasGEF_N domain RICTOR_V PF14668.6 AIN98590.1 - 0.00024 21.3 0.5 0.0086 16.3 0.1 3.5 3 0 0 3 3 3 1 Rapamycin-insensitive companion of mTOR, domain 5 DUF3602 PF12223.8 AIN98590.1 - 0.31 11.7 0.1 0.31 11.7 0.1 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3602) M_domain PF12938.7 AIN98590.1 - 9.2 6.0 9.6 0.49 10.2 1.7 2.3 2 0 0 2 2 2 0 M domain of GW182 XPG_I PF00867.18 AIN98592.1 - 5e-17 62.0 0.2 9.1e-16 58.0 0.1 2.4 2 0 0 2 2 2 1 XPG I-region XPG_N PF00752.17 AIN98592.1 - 7.6e-15 55.2 0.0 3.1e-06 27.6 0.0 2.5 2 0 0 2 2 2 2 XPG N-terminal domain XPG_I_2 PF12813.7 AIN98592.1 - 0.031 13.8 0.3 0.057 12.9 0.3 1.3 1 0 0 1 1 1 0 XPG domain containing FA_hydroxylase PF04116.13 AIN98595.1 - 1.9e-22 80.0 17.8 1.9e-22 80.0 17.8 2.3 2 1 0 2 2 2 1 Fatty acid hydroxylase superfamily DHC_N1 PF08385.12 AIN98596.1 - 5.6e-154 513.9 0.0 5.6e-154 513.9 0.0 4.1 3 2 1 4 4 4 1 Dynein heavy chain, N-terminal region 1 AAA_6 PF12774.7 AIN98596.1 - 1.7e-147 490.7 0.0 6.4e-147 488.8 0.0 2.1 2 0 0 2 2 2 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 AIN98596.1 - 1.2e-112 377.0 11.5 1.2e-112 377.0 11.5 4.6 4 0 0 4 4 4 1 Dynein heavy chain, N-terminal region 2 AAA_8 PF12780.7 AIN98596.1 - 5.1e-98 327.5 0.0 5.1e-98 327.5 0.0 2.3 2 0 0 2 2 2 1 P-loop containing dynein motor region D4 Dynein_C PF18199.1 AIN98596.1 - 3.4e-84 282.7 0.1 1.6e-83 280.5 0.0 2.3 3 0 0 3 3 2 1 Dynein heavy chain C-terminal domain AAA_9 PF12781.7 AIN98596.1 - 3.1e-80 268.4 0.8 3.1e-80 268.4 0.8 3.1 3 0 0 3 3 3 1 ATP-binding dynein motor region AAA_7 PF12775.7 AIN98596.1 - 6.7e-64 214.7 0.9 1.1e-58 197.8 0.0 4.3 4 1 0 4 4 4 2 P-loop containing dynein motor region AAA_lid_11 PF18198.1 AIN98596.1 - 7.4e-53 178.7 0.1 1.8e-52 177.5 0.1 1.7 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain Dynein_heavy PF03028.15 AIN98596.1 - 2e-43 147.2 0.0 4.7e-42 142.8 0.0 3.4 4 0 0 4 4 2 1 Dynein heavy chain region D6 P-loop domain MT PF12777.7 AIN98596.1 - 1.3e-39 136.2 14.4 1.3e-39 136.2 14.4 1.6 2 0 0 2 2 1 1 Microtubule-binding stalk of dynein motor AAA_5 PF07728.14 AIN98596.1 - 1.2e-24 86.8 0.2 1.1e-07 31.9 0.0 6.2 5 1 0 5 5 5 4 AAA domain (dynein-related subfamily) Dynein_AAA_lid PF17852.1 AIN98596.1 - 4.8e-23 81.6 0.0 1.9e-22 79.7 0.0 2.2 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain AAA_lid_1 PF17857.1 AIN98596.1 - 1.3e-16 60.7 0.1 6e-16 58.5 0.1 2.3 1 0 0 1 1 1 1 AAA+ lid domain T2SSE PF00437.20 AIN98596.1 - 2.7e-06 26.6 0.0 0.64 9.0 0.0 4.3 4 0 0 4 4 4 2 Type II/IV secretion system protein AAA_16 PF13191.6 AIN98596.1 - 1.8e-05 25.2 5.9 0.8 10.1 0.0 6.1 5 0 0 5 5 4 1 AAA ATPase domain AAA PF00004.29 AIN98596.1 - 5.1e-05 23.7 0.0 0.46 10.9 0.0 4.0 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 AIN98596.1 - 0.0034 17.7 10.2 2.3 8.5 0.0 6.6 6 0 0 6 6 6 1 AAA domain ABC_tran PF00005.27 AIN98596.1 - 0.024 15.1 1.0 12 6.4 0.0 4.5 4 0 0 4 4 4 0 ABC transporter FtsK_SpoIIIE PF01580.18 AIN98596.1 - 0.052 12.9 0.1 11 5.3 0.0 2.7 2 0 0 2 2 2 0 FtsK/SpoIIIE family Mg_chelatase PF01078.21 AIN98596.1 - 0.13 11.6 0.1 3.3 7.0 0.0 2.7 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.22 AIN98596.1 - 0.13 12.6 0.0 53 4.3 0.0 3.5 3 0 0 3 3 3 0 RNA helicase AAA_18 PF13238.6 AIN98596.1 - 0.18 12.3 2.7 3.3 8.3 0.0 4.3 5 0 0 5 5 3 0 AAA domain AAA_24 PF13479.6 AIN98596.1 - 2.9 7.6 4.6 34 4.1 0.0 4.4 5 0 0 5 5 5 0 AAA domain YceI PF04264.13 AIN98597.1 - 6.9e-05 23.4 0.0 7.8e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 YceI-like domain DNA_pol_B PF00136.21 AIN98598.1 - 3.3e-79 266.7 0.0 4.3e-79 266.4 0.0 1.1 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.19 AIN98598.1 - 0.0001 21.6 0.0 0.041 13.0 0.0 2.3 2 0 0 2 2 2 2 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.6 AIN98598.1 - 0.00034 21.0 1.8 0.001 19.5 0.2 2.6 3 0 0 3 3 3 1 C4-type zinc-finger of DNA polymerase delta Radical_SAM_C PF16199.5 AIN98600.1 - 6.7e-16 58.1 0.2 1.3e-15 57.1 0.2 1.5 1 0 0 1 1 1 1 Radical_SAM C-terminal domain Radical_SAM PF04055.21 AIN98600.1 - 1.2e-14 55.1 0.0 3.4e-14 53.6 0.0 1.8 1 0 0 1 1 1 1 Radical SAM superfamily Acetyltransf_1 PF00583.25 AIN98600.1 - 1.2e-07 32.0 0.2 2.9e-07 30.7 0.2 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 AIN98600.1 - 0.00022 21.2 0.1 0.00062 19.7 0.1 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Hum_adeno_E3A PF05393.11 AIN98601.1 - 0.058 13.4 0.1 0.11 12.5 0.1 1.4 1 0 0 1 1 1 0 Human adenovirus early E3A glycoprotein Mito_carr PF00153.27 AIN98602.1 - 1.9e-37 127.0 0.3 9.4e-17 60.7 0.0 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein Helicase_C PF00271.31 AIN98603.1 - 3.7e-12 46.6 0.0 4.1e-10 40.0 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 AIN98603.1 - 1.3e-10 41.3 0.0 3.2e-10 40.1 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase HHH_5 PF14520.6 AIN98603.1 - 0.008 16.8 0.0 0.02 15.5 0.0 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix domain ResIII PF04851.15 AIN98603.1 - 0.033 14.2 0.0 0.061 13.3 0.0 1.3 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit RTA1 PF04479.13 AIN98604.1 - 0.002 17.8 0.8 0.0025 17.5 0.6 1.2 1 1 0 1 1 1 1 RTA1 like protein MtrD PF04207.12 AIN98604.1 - 0.071 12.8 0.1 0.1 12.2 0.1 1.3 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, subunit D Mog1 PF04603.12 AIN98605.1 - 1.3e-29 103.3 0.0 1.7e-29 103.0 0.0 1.1 1 0 0 1 1 1 1 Ran-interacting Mog1 protein Fer2_3 PF13085.6 AIN98606.1 - 7.6e-31 106.3 0.1 3e-30 104.4 0.0 1.9 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Fer2 PF00111.27 AIN98606.1 - 0.013 15.4 0.7 0.013 15.4 0.7 1.9 2 0 0 2 2 2 0 2Fe-2S iron-sulfur cluster binding domain LUC7 PF03194.15 AIN98606.1 - 0.019 14.6 0.1 0.029 14.0 0.1 1.2 1 0 0 1 1 1 0 LUC7 N_terminus DHHC PF01529.20 AIN98607.1 - 1.5e-31 109.2 13.7 1.5e-31 109.2 13.7 2.2 2 0 0 2 2 2 1 DHHC palmitoyltransferase DHHC PF01529.20 AIN98608.1 - 4.1e-32 111.1 4.4 4.1e-32 111.1 4.4 2.1 2 0 0 2 2 2 1 DHHC palmitoyltransferase BING4CT PF08149.11 AIN98608.1 - 0.063 13.1 0.0 0.14 12.0 0.0 1.5 1 0 0 1 1 1 0 BING4CT (NUC141) domain HemY_N PF07219.13 AIN98608.1 - 0.9 9.8 3.1 33 4.7 0.0 2.7 2 0 0 2 2 2 0 HemY protein N-terminus DHHC PF01529.20 AIN98609.1 - 4.6e-24 85.0 20.5 4.6e-24 85.0 20.5 2.4 2 0 0 2 2 2 1 DHHC palmitoyltransferase PepSY_TM PF03929.16 AIN98609.1 - 0.089 12.4 3.5 0.094 12.4 2.0 1.7 1 1 0 1 1 1 0 PepSY-associated TM region PTPlike_phytase PF14566.6 AIN98610.1 - 1.3e-120 399.0 0.5 2.9e-45 154.2 0.0 3.5 3 0 0 3 3 3 3 Inositol hexakisphosphate Y_phosphatase3 PF13350.6 AIN98610.1 - 0.066 13.2 0.6 5.2 7.0 0.0 3.4 4 0 0 4 4 4 0 Tyrosine phosphatase family ADK PF00406.22 AIN98611.1 - 4e-07 30.3 0.1 0.00031 20.9 0.0 2.8 3 0 0 3 3 3 2 Adenylate kinase AAA_17 PF13207.6 AIN98611.1 - 0.005 17.3 0.0 0.72 10.3 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 AIN98611.1 - 0.0073 16.7 0.2 0.32 11.4 0.1 2.4 1 1 1 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 AIN98611.1 - 0.019 15.5 0.0 0.064 13.8 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA_33 PF13671.6 AIN98611.1 - 0.02 15.0 0.2 0.063 13.4 0.0 2.0 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 AIN98611.1 - 0.034 13.4 1.0 0.055 12.7 0.1 1.8 2 0 0 2 2 2 0 Zeta toxin Phe_hydrox_dim PF07976.12 AIN98611.1 - 0.067 13.2 0.0 0.14 12.2 0.0 1.5 1 0 0 1 1 1 0 Phenol hydroxylase, C-terminal dimerisation domain SurA_N PF09312.11 AIN98611.1 - 0.075 13.1 0.3 0.6 10.2 0.0 2.1 2 0 0 2 2 2 0 SurA N-terminal domain AAA_16 PF13191.6 AIN98611.1 - 0.14 12.5 1.8 0.41 11.0 0.3 2.6 1 1 1 2 2 2 0 AAA ATPase domain AAA_5 PF07728.14 AIN98611.1 - 0.14 12.1 0.0 0.32 11.0 0.0 1.6 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) DUF3619 PF12279.8 AIN98611.1 - 0.18 12.1 1.6 4.3 7.7 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3619) Methyltransf_25 PF13649.6 AIN98612.1 - 0.12 13.1 0.2 3.3 8.5 0.2 2.3 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.6 AIN98612.1 - 0.14 11.9 0.0 0.31 10.8 0.0 1.4 1 1 0 1 1 1 0 Methyltransferase domain MtrF PF09472.10 AIN98613.1 - 0.21 11.0 0.1 0.42 10.0 0.1 1.5 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, F subunit (MtrF) Anoctamin PF04547.12 AIN98614.1 - 0.11 11.4 0.2 0.11 11.3 0.2 1.1 1 0 0 1 1 1 0 Calcium-activated chloride channel Pet100 PF09803.9 AIN98614.1 - 1.8 9.1 6.8 8.1 7.0 6.8 1.9 1 1 0 1 1 1 0 Pet100 zf-rbx1 PF12678.7 AIN98615.1 - 7.1e-13 48.6 6.5 1.3e-12 47.7 6.5 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_2 PF13639.6 AIN98615.1 - 1.3e-09 38.3 7.7 3.3e-08 33.7 4.8 2.3 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.6 AIN98615.1 - 5e-07 29.5 8.8 5.5e-06 26.1 5.8 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 AIN98615.1 - 1.5e-05 24.9 5.5 3.7e-05 23.6 5.5 1.7 1 1 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.25 AIN98615.1 - 2.1e-05 24.3 7.5 4.6e-05 23.2 7.5 1.6 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 AIN98615.1 - 5.3e-05 23.2 3.9 0.00013 22.0 3.9 1.6 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.6 AIN98615.1 - 0.00017 21.6 5.2 0.00021 21.3 1.4 2.4 1 1 1 2 2 2 1 RING-type zinc-finger zf-RING_11 PF17123.5 AIN98615.1 - 0.001 18.8 1.1 0.001 18.8 1.1 2.9 3 0 0 3 3 3 1 RING-like zinc finger zf-C3HC4_3 PF13920.6 AIN98615.1 - 0.0046 16.8 8.4 0.018 14.9 3.9 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 AIN98615.1 - 0.012 15.5 7.5 0.037 13.9 3.7 2.2 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 Zn_ribbon_17 PF17120.5 AIN98615.1 - 0.017 14.7 4.9 0.022 14.4 2.6 2.0 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type zinc_ribbon_16 PF17034.5 AIN98615.1 - 0.019 15.2 1.5 0.038 14.2 1.5 1.5 1 0 0 1 1 1 0 Zinc-ribbon like family zf-Nse PF11789.8 AIN98615.1 - 0.4 10.5 4.0 0.34 10.8 2.4 1.7 2 0 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit FANCL_C PF11793.8 AIN98615.1 - 0.53 10.5 7.7 6.2 7.1 7.8 2.5 1 1 1 2 2 2 0 FANCL C-terminal domain zf-P11 PF03854.14 AIN98615.1 - 0.69 9.6 5.0 0.4 10.4 2.7 1.7 2 0 0 2 2 2 0 P-11 zinc finger RINGv PF12906.7 AIN98615.1 - 4.4 7.5 8.7 1.3 9.2 4.8 1.9 2 0 0 2 2 2 0 RING-variant domain V-SNARE PF05008.15 AIN98616.1 - 2.5e-10 40.6 0.4 1e-07 32.2 0.0 3.1 3 0 0 3 3 3 1 Vesicle transport v-SNARE protein N-terminus Sec20 PF03908.13 AIN98616.1 - 1.2e-06 28.3 0.8 7.6e-06 25.8 0.2 2.3 2 0 0 2 2 2 1 Sec20 V-SNARE_C PF12352.8 AIN98616.1 - 7.8e-06 26.1 1.9 7.8e-06 26.1 1.9 1.7 2 0 0 2 2 2 1 Snare region anchored in the vesicle membrane C-terminus Laminin_I PF06008.14 AIN98616.1 - 0.00077 19.2 4.2 0.022 14.5 1.8 2.3 2 0 0 2 2 2 1 Laminin Domain I Vps51 PF08700.11 AIN98616.1 - 0.037 14.1 2.2 4.8 7.3 0.0 3.7 4 1 1 5 5 5 0 Vps51/Vps67 Syntaxin-6_N PF09177.11 AIN98616.1 - 0.04 14.5 2.9 0.44 11.1 0.1 3.0 2 1 1 3 3 3 0 Syntaxin 6, N-terminal Nup54 PF13874.6 AIN98616.1 - 0.087 12.9 4.7 0.033 14.3 1.1 2.0 1 1 1 2 2 2 0 Nucleoporin complex subunit 54 DUF4618 PF15397.6 AIN98616.1 - 0.31 10.4 4.5 1.4 8.2 0.6 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4618) Uds1 PF15456.6 AIN98616.1 - 0.33 11.1 10.8 0.64 10.2 2.9 2.3 2 1 0 2 2 2 0 Up-regulated During Septation HAUS-augmin3 PF14932.6 AIN98616.1 - 0.96 9.0 7.5 0.26 10.8 0.7 2.1 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 3 Spc7 PF08317.11 AIN98616.1 - 4.1 6.2 8.4 5.3 5.8 0.6 2.3 3 0 0 3 3 3 0 Spc7 kinetochore protein FliJ PF02050.16 AIN98616.1 - 5.6 7.2 9.0 2.3 8.5 0.9 2.4 2 0 0 2 2 2 0 Flagellar FliJ protein Lebercilin PF15619.6 AIN98616.1 - 5.7 6.6 8.2 3.5 7.2 0.7 2.8 3 1 0 3 3 3 0 Ciliary protein causing Leber congenital amaurosis disease V-SNARE PF05008.15 AIN98617.1 - 2.2e-12 47.1 3.7 2.9e-12 46.8 0.1 2.8 3 0 0 3 3 3 1 Vesicle transport v-SNARE protein N-terminus V-SNARE_C PF12352.8 AIN98617.1 - 4.7e-07 30.0 0.8 9.2e-07 29.1 0.8 1.5 1 0 0 1 1 1 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.13 AIN98617.1 - 7e-06 25.9 1.9 1.3e-05 25.0 1.2 1.8 2 0 0 2 2 2 1 Sec20 Unstab_antitox PF09720.10 AIN98617.1 - 0.0023 17.9 0.3 0.03 14.4 0.0 2.6 2 0 0 2 2 2 1 Putative addiction module component KASH_CCD PF14662.6 AIN98617.1 - 0.0085 15.9 5.2 0.49 10.2 1.3 2.2 2 0 0 2 2 2 2 Coiled-coil region of CCDC155 or KASH Synaptobrevin PF00957.21 AIN98617.1 - 0.014 15.1 2.1 0.034 13.9 2.1 1.7 1 0 0 1 1 1 0 Synaptobrevin TraG_N PF07916.11 AIN98617.1 - 0.016 14.1 0.1 0.021 13.7 0.1 1.1 1 0 0 1 1 1 0 TraG-like protein, N-terminal region Baculo_F PF12259.8 AIN98617.1 - 0.045 12.3 1.0 0.089 11.3 0.2 1.7 2 0 0 2 2 2 0 Baculovirus F protein DUF745 PF05335.13 AIN98617.1 - 0.05 13.3 9.0 2.4 7.9 5.4 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF745) ODV-E18 PF10717.9 AIN98617.1 - 0.097 12.5 0.4 0.2 11.6 0.4 1.5 1 0 0 1 1 1 0 Occlusion-derived virus envelope protein ODV-E18 Spc7 PF08317.11 AIN98617.1 - 0.11 11.4 4.5 0.19 10.6 4.5 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein Spore_III_AB PF09548.10 AIN98617.1 - 0.11 12.6 2.3 0.41 10.7 0.1 2.3 2 1 0 2 2 2 0 Stage III sporulation protein AB (spore_III_AB) MRAP PF15183.6 AIN98617.1 - 0.15 12.0 0.0 0.28 11.1 0.0 1.4 1 0 0 1 1 1 0 Melanocortin-2 receptor accessory protein family CSN5_C PF18323.1 AIN98617.1 - 0.54 11.2 5.4 0.15 13.0 1.5 2.0 2 1 0 2 2 2 0 Cop9 signalosome subunit 5 C-terminal domain Fez1 PF06818.15 AIN98617.1 - 0.69 10.3 5.4 0.83 10.1 0.9 2.2 1 1 1 2 2 2 0 Fez1 DUF883 PF05957.13 AIN98617.1 - 0.85 10.3 13.6 0.9 10.2 1.2 3.2 2 1 2 4 4 4 0 Bacterial protein of unknown function (DUF883) EXOSC1 PF10447.9 AIN98619.1 - 0.0012 19.4 0.0 0.052 14.2 0.0 2.3 1 1 0 1 1 1 1 Exosome component EXOSC1/CSL4 TPH PF13868.6 AIN98621.1 - 2e-33 115.4 127.9 2e-33 115.4 127.9 2.1 2 0 0 2 2 2 2 Trichohyalin-plectin-homology domain TIP41 PF04176.13 AIN98622.1 - 8e-22 77.5 0.0 1.3e-21 76.9 0.0 1.3 1 0 0 1 1 1 1 TIP41-like family GAF_2 PF13185.6 AIN98622.1 - 3.1e-10 40.5 0.0 6.1e-10 39.5 0.0 1.5 1 0 0 1 1 1 1 GAF domain GAF PF01590.26 AIN98622.1 - 4.8e-07 30.5 0.0 1e-06 29.4 0.0 1.6 1 0 0 1 1 1 1 GAF domain LRR_4 PF12799.7 AIN98623.1 - 1.8e-05 25.0 5.0 0.0015 18.9 0.1 3.0 1 1 1 3 3 3 2 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 AIN98623.1 - 0.0052 16.3 0.1 0.0077 15.7 0.1 1.3 1 0 0 1 1 1 1 Leucine-rich repeat CDC45 PF02724.14 AIN98623.1 - 0.032 12.5 6.9 0.036 12.4 6.9 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF2183 PF09949.9 AIN98623.1 - 0.11 12.8 0.0 0.21 11.9 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2183) LRR_8 PF13855.6 AIN98623.1 - 0.37 10.6 4.9 7.1 6.5 0.1 2.9 2 2 0 2 2 2 0 Leucine rich repeat LRR_6 PF13516.6 AIN98623.1 - 0.4 10.9 3.0 5.9 7.2 0.0 3.4 4 0 0 4 4 4 0 Leucine Rich repeat Nop14 PF04147.12 AIN98623.1 - 4.7 5.3 10.2 5.2 5.2 10.2 1.1 1 0 0 1 1 1 0 Nop14-like family Ala_racemase_N PF01168.20 AIN98624.1 - 5.4e-21 75.3 0.0 6.3e-21 75.0 0.0 1.0 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain LRR_8 PF13855.6 AIN98625.1 - 2.1e-08 33.8 4.6 0.025 14.3 0.2 5.4 4 2 0 4 4 4 3 Leucine rich repeat LRR_1 PF00560.33 AIN98625.1 - 1.8e-07 30.7 1.7 4.6 8.2 0.1 5.4 5 1 0 5 5 5 3 Leucine Rich Repeat LRR_4 PF12799.7 AIN98625.1 - 6.9e-07 29.5 6.4 0.36 11.3 0.6 4.9 4 1 0 4 4 4 4 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 AIN98625.1 - 5e-05 23.0 6.1 0.59 10.3 0.9 3.8 3 0 0 3 3 3 3 Leucine Rich repeat DUF3318 PF11780.8 AIN98625.1 - 0.16 11.9 0.0 0.28 11.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3318) DUF1618 PF07762.14 AIN98626.1 - 1.9 9.1 5.2 1.2 9.8 0.5 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF1618) V_ATPase_I PF01496.19 AIN98627.1 - 3.4e-260 865.4 22.2 1.8e-176 588.6 0.7 3.0 1 1 2 3 3 3 3 V-type ATPase 116kDa subunit family Osmo_CC PF08946.10 AIN98627.1 - 0.79 10.0 3.0 0.98 9.7 1.2 2.1 2 0 0 2 2 2 0 Osmosensory transporter coiled coil Atg14 PF10186.9 AIN98627.1 - 1.1 8.3 2.8 4.7 6.2 2.8 1.9 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Orai-1 PF07856.12 AIN98627.1 - 2.4 7.8 6.8 0.25 11.0 0.6 2.3 1 1 0 2 2 2 0 Mediator of CRAC channel activity UbiA PF01040.18 AIN98628.1 - 1.1e-49 169.0 22.1 1.5e-49 168.5 22.1 1.2 1 0 0 1 1 1 1 UbiA prenyltransferase family NRDE-2 PF08424.10 AIN98631.1 - 1e-05 24.8 3.1 0.03 13.4 0.1 4.3 3 1 1 4 4 4 3 NRDE-2, necessary for RNA interference TPR_19 PF14559.6 AIN98631.1 - 0.19 12.2 5.5 17 6.0 0.0 5.5 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_9 PF13371.6 AIN98631.1 - 1.2 9.3 5.9 4.3 7.6 0.1 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.6 AIN98631.1 - 1.4 10.0 25.3 8.8 7.4 0.0 8.8 8 2 2 10 10 10 0 Tetratricopeptide repeat Beach PF02138.18 AIN98633.1 - 6e-88 294.8 0.0 7.8e-88 294.4 0.0 1.1 1 0 0 1 1 1 1 Beige/BEACH domain HBM PF16591.5 AIN98633.1 - 0.0072 15.8 0.0 0.011 15.1 0.0 1.2 1 0 0 1 1 1 1 Helical bimodular sensor domain Nuc_deoxyrib_tr PF05014.15 AIN98634.1 - 2.7e-37 127.7 0.0 3.2e-37 127.5 0.0 1.1 1 0 0 1 1 1 1 Nucleoside 2-deoxyribosyltransferase Nuc_deoxyri_tr2 PF15891.5 AIN98634.1 - 0.014 15.7 0.0 0.02 15.2 0.0 1.3 1 0 0 1 1 1 0 Nucleoside 2-deoxyribosyltransferase like DUF4406 PF14359.6 AIN98634.1 - 0.031 14.8 0.0 0.047 14.2 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4406) Nuc_deoxyri_tr3 PF11071.8 AIN98634.1 - 0.076 13.1 0.0 0.1 12.6 0.0 1.2 1 0 0 1 1 1 0 Nucleoside 2-deoxyribosyltransferase YtoQ CENP-T_C PF15511.6 AIN98635.1 - 1.4e-05 25.1 0.1 2.5e-05 24.3 0.1 1.4 1 1 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CBFD_NFYB_HMF PF00808.23 AIN98635.1 - 0.0002 21.6 0.3 0.00055 20.2 0.0 1.8 2 1 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TAF PF02969.17 AIN98635.1 - 0.00038 20.6 0.1 0.00069 19.7 0.1 1.4 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) Bromo_TP PF07524.13 AIN98635.1 - 0.0016 18.4 0.0 0.0024 17.8 0.0 1.4 1 0 0 1 1 1 1 Bromodomain associated Histone PF00125.24 AIN98635.1 - 0.0035 17.7 2.0 0.0075 16.6 2.0 1.5 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID-31kDa PF02291.15 AIN98635.1 - 0.064 13.3 0.0 0.092 12.8 0.0 1.2 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit BCDHK_Adom3 PF10436.9 AIN98636.1 - 7.1e-26 91.0 0.0 4.2e-25 88.5 0.0 1.9 1 1 1 2 2 2 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.26 AIN98636.1 - 0.08 13.4 0.0 0.15 12.5 0.0 1.5 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase ANTH PF07651.16 AIN98637.1 - 9.3e-25 87.1 0.1 1.4e-24 86.6 0.1 1.3 1 0 0 1 1 1 1 ANTH domain ENTH PF01417.20 AIN98637.1 - 0.00074 19.6 0.1 0.0013 18.7 0.1 1.4 1 0 0 1 1 1 1 ENTH domain Rz1 PF06085.11 AIN98637.1 - 0.031 14.0 0.9 0.031 14.0 0.9 2.2 2 0 0 2 2 2 0 Lipoprotein Rz1 precursor Ribosomal_L22 PF00237.19 AIN98639.1 - 7.1e-32 109.7 0.3 8.8e-32 109.4 0.3 1.1 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e FAM92 PF06730.11 AIN98642.1 - 0.028 13.9 0.4 0.098 12.1 0.0 2.1 2 0 0 2 2 2 0 FAM92 protein zf-RING_2 PF13639.6 AIN98643.1 - 4.1e-08 33.4 5.7 4.1e-08 33.4 5.7 5.3 3 2 1 4 4 4 1 Ring finger domain zf-RING_11 PF17123.5 AIN98643.1 - 3.2e-07 30.0 5.1 2.1e-06 27.3 5.1 2.6 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_UBOX PF13445.6 AIN98643.1 - 1.2e-05 25.3 2.6 1.2e-05 25.3 2.6 3.4 3 1 0 3 3 3 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 AIN98643.1 - 0.0001 22.1 2.6 0.0001 22.1 2.6 3.9 5 0 0 5 5 5 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 AIN98643.1 - 0.00011 21.9 1.7 0.00011 21.9 1.7 4.0 3 1 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 AIN98643.1 - 0.00059 19.7 3.8 0.00059 19.7 3.8 4.7 4 2 1 5 5 5 1 zinc-RING finger domain zf-rbx1 PF12678.7 AIN98643.1 - 0.00064 20.0 3.1 0.00064 20.0 3.1 4.1 2 1 1 3 3 3 1 RING-H2 zinc finger domain DUF3592 PF12158.8 AIN98644.1 - 6.9e-09 35.9 0.1 8.8e-09 35.6 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3592) Enkurin PF13864.6 AIN98645.1 - 7.5e-17 61.6 1.0 1e-16 61.1 1.0 1.2 1 0 0 1 1 1 1 Calmodulin-binding PARP_regulatory PF01358.18 AIN98646.1 - 1.5e-11 43.8 0.0 2.3e-11 43.2 0.0 1.2 1 0 0 1 1 1 1 Poly A polymerase regulatory subunit UPF0182 PF03699.13 AIN98646.1 - 0.051 11.7 0.0 0.072 11.2 0.0 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0182) WD40 PF00400.32 AIN98647.1 - 0.025 15.5 11.0 11 7.0 0.0 4.7 4 0 0 4 4 4 0 WD domain, G-beta repeat Blt1_C PF17183.4 AIN98647.1 - 0.2 11.3 0.0 0.42 10.3 0.0 1.4 1 0 0 1 1 1 0 Get5 carboxyl domain Ank_2 PF12796.7 AIN98648.1 - 6.1e-37 126.1 7.0 1.3e-16 61.0 0.9 4.4 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 AIN98648.1 - 2.6e-36 123.5 9.8 2.4e-10 40.7 0.0 4.9 2 2 4 6 6 6 6 Ankyrin repeats (many copies) Ank_5 PF13857.6 AIN98648.1 - 5.4e-33 112.6 6.8 1.1e-10 41.6 0.1 5.2 2 1 3 5 5 5 5 Ankyrin repeats (many copies) Ank PF00023.30 AIN98648.1 - 1.5e-29 101.1 5.1 2.8e-06 27.5 0.0 7.4 7 0 0 7 7 7 6 Ankyrin repeat Ank_3 PF13606.6 AIN98648.1 - 4.1e-28 94.3 4.2 9.3e-05 22.6 0.0 7.2 7 0 0 7 7 7 6 Ankyrin repeat TPR_1 PF00515.28 AIN98648.1 - 6e-11 41.7 1.5 0.0063 16.3 0.0 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 AIN98648.1 - 3.1e-08 33.1 1.4 0.15 12.3 0.0 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.6 AIN98648.1 - 8.4e-05 22.2 1.2 0.0046 16.6 0.3 3.0 2 1 1 3 3 3 1 TPR repeat TPR_17 PF13431.6 AIN98648.1 - 0.00011 22.3 2.4 0.7 10.4 0.0 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat ANAPC3 PF12895.7 AIN98648.1 - 0.012 15.8 1.4 0.029 14.6 1.4 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 BAT PF15915.5 AIN98648.1 - 0.057 13.3 0.0 0.13 12.2 0.0 1.6 1 0 0 1 1 1 0 GAF and HTH_10 associated domain TPR_8 PF13181.6 AIN98648.1 - 0.13 12.6 0.3 41 4.7 0.0 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat PEX11 PF05648.14 AIN98649.1 - 6e-11 42.2 2.9 4e-07 29.7 0.1 2.1 1 1 1 2 2 2 2 Peroxisomal biogenesis factor 11 (PEX11) AcetylCoA_hyd_C PF13336.6 AIN98649.1 - 0.025 14.5 0.3 1.7 8.5 0.1 2.2 2 0 0 2 2 2 0 Acetyl-CoA hydrolase/transferase C-terminal domain Phosducin PF02114.16 AIN98651.1 - 2e-07 30.2 0.0 2.5e-07 29.9 0.0 1.1 1 0 0 1 1 1 1 Phosducin MRC1 PF09444.10 AIN98651.1 - 0.028 14.9 1.0 0.044 14.3 1.0 1.3 1 0 0 1 1 1 0 MRC1-like domain Pertus-S5-tox PF09276.10 AIN98651.1 - 0.16 12.0 0.0 0.32 11.1 0.0 1.4 1 0 0 1 1 1 0 Pertussis toxin S5 subunit AAA PF00004.29 AIN98652.1 - 4.9e-31 107.9 0.0 1.5e-26 93.4 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 AIN98652.1 - 7.1e-11 42.5 0.0 0.00076 19.8 0.0 3.2 2 1 1 3 3 3 2 AAA domain NACHT PF05729.12 AIN98652.1 - 1.2e-09 38.4 0.3 9.5e-05 22.4 0.1 3.1 2 1 0 2 2 2 2 NACHT domain AAA_16 PF13191.6 AIN98652.1 - 2.3e-07 31.3 9.5 0.00012 22.5 0.1 4.2 2 2 1 3 3 3 1 AAA ATPase domain AAA_5 PF07728.14 AIN98652.1 - 1e-06 28.8 0.0 0.00028 20.9 0.0 2.8 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) RNA_helicase PF00910.22 AIN98652.1 - 3.2e-06 27.5 0.0 0.0024 18.2 0.0 2.5 2 0 0 2 2 2 1 RNA helicase RsgA_GTPase PF03193.16 AIN98652.1 - 4.4e-06 26.7 0.3 0.012 15.6 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA_33 PF13671.6 AIN98652.1 - 9.1e-06 25.9 0.1 0.011 15.9 0.0 2.4 2 0 0 2 2 2 2 AAA domain ABC_tran PF00005.27 AIN98652.1 - 5.4e-05 23.7 0.7 0.16 12.5 0.1 2.4 2 0 0 2 2 2 2 ABC transporter AAA_29 PF13555.6 AIN98652.1 - 6.5e-05 22.6 1.4 0.14 11.9 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain DUF815 PF05673.13 AIN98652.1 - 8e-05 21.9 0.0 0.052 12.7 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF815) AAA_7 PF12775.7 AIN98652.1 - 0.00013 21.6 0.0 0.59 9.6 0.0 2.3 2 0 0 2 2 2 2 P-loop containing dynein motor region TsaE PF02367.17 AIN98652.1 - 0.00018 21.5 0.1 0.5 10.4 0.1 2.3 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_28 PF13521.6 AIN98652.1 - 0.00026 21.3 0.0 0.015 15.6 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_24 PF13479.6 AIN98652.1 - 0.00054 19.7 0.1 1.1 8.9 0.0 2.5 2 1 0 2 2 2 2 AAA domain Rad17 PF03215.15 AIN98652.1 - 0.00079 19.4 0.7 0.12 12.3 0.1 2.6 3 0 0 3 3 2 1 Rad17 P-loop domain NB-ARC PF00931.22 AIN98652.1 - 0.0012 18.1 0.0 0.17 11.1 0.0 2.3 2 0 0 2 2 2 1 NB-ARC domain AAA_25 PF13481.6 AIN98652.1 - 0.0013 18.4 0.3 0.54 9.8 0.0 2.6 2 1 0 2 2 2 1 AAA domain AAA_30 PF13604.6 AIN98652.1 - 0.0018 18.0 0.0 0.14 11.9 0.0 2.5 2 0 0 2 2 2 1 AAA domain Mg_chelatase PF01078.21 AIN98652.1 - 0.0019 17.6 0.0 0.17 11.3 0.0 2.6 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.26 AIN98652.1 - 0.0032 17.2 0.0 0.15 11.8 0.0 2.3 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_14 PF13173.6 AIN98652.1 - 0.0038 17.3 0.0 0.91 9.6 0.0 2.3 2 0 0 2 2 2 1 AAA domain TIP49 PF06068.13 AIN98652.1 - 0.0043 16.3 0.0 0.0083 15.4 0.0 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_8 PF12780.7 AIN98652.1 - 0.005 16.2 0.0 0.064 12.6 0.0 2.1 2 0 0 2 2 2 1 P-loop containing dynein motor region D4 ATPase_2 PF01637.18 AIN98652.1 - 0.0052 16.7 0.0 0.33 10.8 0.0 2.6 3 0 0 3 3 2 1 ATPase domain predominantly from Archaea AAA_23 PF13476.6 AIN98652.1 - 0.007 16.9 0.4 3.3 8.2 0.1 2.2 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 AIN98652.1 - 0.0073 16.9 0.0 0.19 12.3 0.0 2.4 2 0 0 2 2 2 1 AAA domain Viral_helicase1 PF01443.18 AIN98652.1 - 0.0088 15.8 0.0 1.6 8.4 0.0 2.6 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase Zeta_toxin PF06414.12 AIN98652.1 - 0.012 14.9 0.2 0.87 8.8 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin IstB_IS21 PF01695.17 AIN98652.1 - 0.016 15.0 0.0 0.16 11.6 0.0 2.4 3 0 0 3 3 3 0 IstB-like ATP binding protein AAA_PrkA PF08298.11 AIN98652.1 - 0.019 13.9 0.0 0.089 11.7 0.0 1.8 2 0 0 2 2 2 0 PrkA AAA domain PRK PF00485.18 AIN98652.1 - 0.019 14.7 0.1 1.7 8.4 0.0 2.3 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family TniB PF05621.11 AIN98652.1 - 0.026 13.9 0.0 9 5.6 0.0 2.6 3 0 0 3 3 3 0 Bacterial TniB protein FtsK_SpoIIIE PF01580.18 AIN98652.1 - 0.027 13.8 0.7 0.12 11.7 0.1 2.3 3 0 0 3 3 2 0 FtsK/SpoIIIE family Roc PF08477.13 AIN98652.1 - 0.027 14.7 0.0 6.6 7.0 0.0 2.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Cytidylate_kin PF02224.18 AIN98652.1 - 0.035 13.8 0.0 0.078 12.7 0.0 1.6 2 0 0 2 2 1 0 Cytidylate kinase G-alpha PF00503.20 AIN98652.1 - 0.081 12.1 0.4 7.1 5.7 0.0 2.1 2 0 0 2 2 2 0 G-protein alpha subunit MMR_HSR1 PF01926.23 AIN98652.1 - 0.084 13.0 0.0 10 6.2 0.1 2.4 2 0 0 2 2 2 0 50S ribosome-binding GTPase Sigma54_activ_2 PF14532.6 AIN98652.1 - 0.088 12.9 0.0 5.7 7.0 0.0 2.8 2 0 0 2 2 2 0 Sigma-54 interaction domain SIP1 PF04938.12 AIN98652.1 - 0.23 11.1 0.9 0.95 9.1 0.2 2.1 2 0 0 2 2 2 0 Survival motor neuron (SMN) interacting protein 1 (SIP1) NTP_transf_3 PF12804.7 AIN98652.1 - 0.4 11.0 4.3 0.43 10.9 0.2 2.5 2 1 0 2 2 2 0 MobA-like NTP transferase domain HEAT PF02985.22 AIN98653.1 - 9.2e-11 41.0 19.4 0.58 10.6 0.0 7.8 7 0 0 7 7 7 5 HEAT repeat HEAT_2 PF13646.6 AIN98653.1 - 5.9e-09 36.2 13.5 0.0052 17.2 0.0 4.7 4 1 0 4 4 4 3 HEAT repeats Vac14_Fab1_bd PF12755.7 AIN98653.1 - 9e-05 23.0 0.8 2.1 9.0 0.1 4.4 4 0 0 4 4 4 2 Vacuolar 14 Fab1-binding region Cnd1 PF12717.7 AIN98653.1 - 0.00073 19.6 0.1 6.4 6.8 0.0 3.4 3 1 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.20 AIN98653.1 - 0.006 15.2 0.6 0.38 9.2 0.0 3.2 2 2 0 3 3 3 1 Adaptin N terminal region TFIIS_M PF07500.14 AIN98655.1 - 7.8e-18 65.0 1.1 1.4e-17 64.2 1.1 1.3 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS), central domain TFIIS_C PF01096.18 AIN98655.1 - 1.8e-14 53.3 4.1 3e-14 52.6 4.1 1.4 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS) Baculo_LEF5_C PF11792.8 AIN98655.1 - 0.0001 21.9 0.5 0.0003 20.4 0.5 1.9 2 0 0 2 2 2 1 Baculoviridae late expression factor 5 C-terminal domain zf-DNL PF05180.12 AIN98655.1 - 0.01 15.8 0.5 0.023 14.6 0.5 1.6 1 0 0 1 1 1 0 DNL zinc finger CBP4 PF07960.11 AIN98655.1 - 0.029 14.2 0.1 0.067 13.0 0.1 1.6 1 0 0 1 1 1 0 CBP4 UCH_1 PF13423.6 AIN98655.1 - 0.036 13.7 0.7 0.047 13.3 0.7 1.2 1 0 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase Elf1 PF05129.13 AIN98655.1 - 0.055 13.5 1.1 0.11 12.5 1.1 1.4 1 0 0 1 1 1 0 Transcription elongation factor Elf1 like U83 PF17465.2 AIN98655.1 - 0.1 12.7 0.3 3.8 7.7 0.0 2.7 2 1 0 2 2 2 0 Chemokine-like protein, HHV-6 U83 gene product zf-CSL PF05207.13 AIN98655.1 - 0.1 12.3 0.3 0.18 11.6 0.3 1.4 1 0 0 1 1 1 0 CSL zinc finger Pkinase PF00069.25 AIN98656.1 - 7.6e-52 176.3 0.0 6.7e-51 173.2 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 AIN98656.1 - 1.9e-26 92.9 0.0 2.4e-19 69.7 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase FHA PF00498.26 AIN98656.1 - 7.6e-14 51.8 0.1 1.9e-13 50.5 0.1 1.7 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 AIN98656.1 - 8.9e-09 35.6 0.0 3.1e-08 33.8 0.0 1.9 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain APH PF01636.23 AIN98656.1 - 0.00035 20.6 0.2 0.26 11.2 0.0 2.8 2 1 1 3 3 3 2 Phosphotransferase enzyme family Kinase-like PF14531.6 AIN98656.1 - 0.049 12.9 0.0 0.21 10.9 0.0 2.0 3 0 0 3 3 3 0 Kinase-like RIO1 PF01163.22 AIN98656.1 - 0.14 11.7 0.0 0.22 11.1 0.0 1.2 1 0 0 1 1 1 0 RIO1 family CAF1C_H4-bd PF12265.8 AIN98657.1 - 1.8e-10 40.9 0.1 5.3e-10 39.4 0.1 1.9 2 0 0 2 2 2 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex ANAPC4_WD40 PF12894.7 AIN98657.1 - 0.0015 18.7 2.5 0.69 10.3 0.2 3.8 1 1 3 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 AIN98657.1 - 0.018 15.9 0.3 0.018 15.9 0.3 5.0 5 0 0 5 5 5 0 WD domain, G-beta repeat DEAD PF00270.29 AIN98658.1 - 2.4e-32 112.1 0.3 6.4e-32 110.7 0.3 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 AIN98658.1 - 2.8e-16 59.8 0.0 1e-15 58.0 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 AIN98658.1 - 4.2e-07 30.1 0.0 1.4e-06 28.4 0.0 1.9 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit Metallophos PF00149.28 AIN98660.1 - 1.6e-07 32.0 0.0 3.4e-06 27.7 0.0 2.3 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase FSA_C PF10479.9 AIN98660.1 - 6.6 4.7 6.6 14 3.7 6.6 1.4 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus WD40 PF00400.32 AIN98661.1 - 2.7e-07 31.1 5.0 0.018 15.9 0.1 3.8 3 0 0 3 3 3 2 WD domain, G-beta repeat tify PF06200.14 AIN98661.1 - 0.65 9.4 5.3 1.8 8.0 0.2 2.8 3 0 0 3 3 3 0 tify domain NIF PF03031.18 AIN98662.1 - 1.7e-31 109.1 0.6 2.4e-31 108.6 0.6 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Hydrolase PF00702.26 AIN98662.1 - 0.036 14.4 0.5 1.2 9.4 0.0 3.0 3 1 1 4 4 4 0 haloacid dehalogenase-like hydrolase DUF2608 PF11019.8 AIN98662.1 - 0.11 12.0 1.0 2 7.8 0.0 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2608) zf-RING_2 PF13639.6 AIN98663.1 - 2.1e-05 24.8 8.9 7e-05 23.1 8.9 2.0 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 AIN98663.1 - 0.035 14.4 8.6 0.16 12.3 8.6 2.3 1 0 0 1 1 1 0 RING-H2 zinc finger domain Ribonuc_P_40 PF08584.11 AIN98663.1 - 0.084 12.1 1.3 0.22 10.7 0.0 2.2 2 0 0 2 2 2 0 Ribonuclease P 40kDa (Rpp40) subunit zf-C3HC4 PF00097.25 AIN98663.1 - 0.23 11.4 7.6 0.63 10.0 7.6 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) RINGv PF12906.7 AIN98663.1 - 0.51 10.5 7.4 1.5 9.0 7.4 1.9 1 0 0 1 1 1 0 RING-variant domain FANCL_C PF11793.8 AIN98663.1 - 0.57 10.4 9.9 0.086 13.0 5.0 2.2 2 0 0 2 2 2 0 FANCL C-terminal domain zf-C3HC4_3 PF13920.6 AIN98663.1 - 1.6 8.7 4.6 3.9 7.4 4.6 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Fumerase_C PF05683.12 AIN98665.1 - 8.7e-86 286.5 0.0 2.5e-85 285.0 0.0 1.7 2 0 0 2 2 2 1 Fumarase C-terminus Fumerase PF05681.14 AIN98665.1 - 3e-80 269.5 0.0 4.1e-80 269.1 0.0 1.1 1 0 0 1 1 1 1 Fumarate hydratase (Fumerase) Rsm22 PF09243.10 AIN98666.1 - 7.4e-29 100.9 4.9 1.7e-17 63.6 0.2 3.1 4 0 0 4 4 4 2 Mitochondrial small ribosomal subunit Rsm22 Phosphodiest PF01663.22 AIN98667.1 - 1.8e-10 40.9 0.0 3.8e-10 39.9 0.0 1.5 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 AIN98667.1 - 0.081 12.3 0.0 0.14 11.5 0.0 1.3 1 0 0 1 1 1 0 Sulfatase MerE PF05052.12 AIN98668.1 - 0.18 11.7 2.1 0.68 9.9 0.8 2.1 2 0 0 2 2 2 0 MerE protein Aminotran_1_2 PF00155.21 AIN98669.1 - 7.1e-71 239.3 0.0 8e-71 239.1 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II DUF512 PF04459.12 AIN98669.1 - 0.018 14.3 0.0 0.79 9.0 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF512) Toxin_10 PF05431.11 AIN98671.1 - 0.072 12.5 0.1 0.15 11.5 0.1 1.4 1 0 0 1 1 1 0 Insecticidal Crystal Toxin, P42 TPR_2 PF07719.17 AIN98672.1 - 0.0032 17.5 0.1 1.5 9.1 0.1 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat NAD_binding_9 PF13454.6 AIN98672.1 - 0.0095 15.9 1.0 0.085 12.8 0.2 2.2 2 0 0 2 2 2 1 FAD-NAD(P)-binding SET PF00856.28 AIN98672.1 - 0.077 13.4 0.1 0.16 12.3 0.1 1.6 1 0 0 1 1 1 0 SET domain Peptidase_C12 PF01088.21 AIN98674.1 - 1.3e-57 195.0 0.0 1.7e-57 194.6 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 UCH_C PF18031.1 AIN98674.1 - 4.6e-12 45.7 0.7 1e-11 44.5 0.7 1.6 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolases Nuc_sug_transp PF04142.15 AIN98676.1 - 4.1e-57 193.7 22.7 7.4e-55 186.3 18.2 2.7 3 0 0 3 3 3 2 Nucleotide-sugar transporter EamA PF00892.20 AIN98676.1 - 4 7.6 32.9 0.069 13.3 3.8 3.1 3 1 0 3 3 3 0 EamA-like transporter family Stealth_CR2 PF11380.8 AIN98677.1 - 4.6e-11 42.8 0.0 7.8e-09 35.7 0.0 2.7 2 0 0 2 2 2 2 Stealth protein CR2, conserved region 2 Stealth_CR3 PF17102.5 AIN98677.1 - 0.045 13.6 7.9 0.036 14.0 0.7 2.9 2 0 0 2 2 2 0 Stealth protein CR3, conserved region 3 OEP PF02321.18 AIN98678.1 - 0.12 12.2 0.0 5.5 6.7 0.1 2.1 2 0 0 2 2 2 0 Outer membrane efflux protein Kelch_4 PF13418.6 AIN98679.1 - 1.5e-28 98.5 7.3 1.4e-06 28.2 0.0 7.4 5 2 1 6 6 6 4 Galactose oxidase, central domain Kelch_5 PF13854.6 AIN98679.1 - 2.5e-19 68.8 5.8 3.2e-08 33.4 0.0 6.3 7 0 0 7 7 7 3 Kelch motif Kelch_6 PF13964.6 AIN98679.1 - 1.6e-13 50.4 5.9 0.0058 16.9 0.0 6.9 6 1 1 7 7 7 4 Kelch motif Kelch_2 PF07646.15 AIN98679.1 - 4e-08 32.9 0.2 0.078 13.0 0.0 5.3 5 0 0 5 5 5 2 Kelch motif Kelch_3 PF13415.6 AIN98679.1 - 1.7e-07 31.3 20.5 0.0017 18.6 0.1 9.8 12 0 0 12 12 12 2 Galactose oxidase, central domain Kelch_1 PF01344.25 AIN98679.1 - 7.8e-06 25.4 4.4 0.048 13.2 0.0 5.8 6 0 0 6 6 6 1 Kelch motif zf-CGNR PF11706.8 AIN98679.1 - 0.88 9.5 7.1 0.31 10.9 0.1 3.0 2 0 0 2 2 2 0 CGNR zinc finger LRR_4 PF12799.7 AIN98680.1 - 1.5e-39 133.3 55.4 2.5e-05 24.5 0.4 13.6 9 3 4 13 13 13 12 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 AIN98680.1 - 1.2e-38 130.7 66.2 2.6e-07 30.3 0.7 11.5 7 4 3 10 10 10 9 Leucine rich repeat LRR_9 PF14580.6 AIN98680.1 - 4.2e-34 117.5 19.5 3.1e-08 33.3 0.0 8.2 6 3 3 9 9 9 8 Leucine-rich repeat LRR_6 PF13516.6 AIN98680.1 - 1.7e-05 24.5 40.9 5.1 7.4 0.0 14.8 17 0 0 17 17 17 4 Leucine Rich repeat CbeA_antitoxin PF06154.11 AIN98680.1 - 0.16 12.6 0.0 0.67 10.6 0.0 2.1 1 0 0 1 1 1 0 CbeA_antitoxin, type IV, cytoskeleton bundling-enhancing factor A Dicer_dimer PF03368.14 AIN98681.1 - 0.1 12.8 0.2 0.23 11.7 0.1 1.6 2 0 0 2 2 2 0 Dicer dimerisation domain MPP6 PF10175.9 AIN98681.1 - 0.19 12.3 2.0 0.28 11.7 0.2 2.0 2 0 0 2 2 2 0 M-phase phosphoprotein 6 DUF1664 PF07889.12 AIN98682.1 - 0.0061 16.6 2.9 0.0061 16.6 2.9 3.4 3 1 1 4 4 4 1 Protein of unknown function (DUF1664) TetR_C_26 PF17934.1 AIN98682.1 - 0.037 14.3 4.0 0.12 12.7 4.0 1.9 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain Cbl_N PF02262.16 AIN98682.1 - 0.078 13.0 4.9 0.19 11.7 0.0 3.1 3 0 0 3 3 3 0 CBL proto-oncogene N-terminal domain 1 CENP-T_C PF15511.6 AIN98682.1 - 2.6 8.2 7.4 0.56 10.3 3.5 2.0 2 0 0 2 2 2 0 Centromere kinetochore component CENP-T histone fold TFIID-31kDa PF02291.15 AIN98683.1 - 0.00072 19.6 0.1 0.0015 18.6 0.1 1.5 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit DnaJ PF00226.31 AIN98683.1 - 0.1 12.7 0.1 0.23 11.6 0.1 1.7 1 0 0 1 1 1 0 DnaJ domain ENT PF03735.14 AIN98684.1 - 0.00042 20.3 0.0 0.001 19.1 0.0 1.6 1 0 0 1 1 1 1 ENT domain TRM13 PF05206.14 AIN98686.1 - 1.8e-06 27.7 0.0 2.6e-06 27.2 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase TRM13 TRM13 PF05206.14 AIN98687.1 - 3.2e-19 69.5 0.0 1.4e-18 67.4 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase TRM13 Methyltransf_32 PF13679.6 AIN98687.1 - 0.00011 22.2 1.0 0.00065 19.7 1.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Sigma70_r4 PF04545.16 AIN98687.1 - 0.073 12.6 0.7 4.8 6.8 0.0 2.5 2 0 0 2 2 2 0 Sigma-70, region 4 LapA_dom PF06305.11 AIN98688.1 - 0.00056 19.7 0.2 0.00085 19.1 0.2 1.3 1 0 0 1 1 1 1 Lipopolysaccharide assembly protein A domain WBP-1 PF11669.8 AIN98688.1 - 0.0081 16.8 0.5 0.016 15.8 0.5 1.5 1 1 0 1 1 1 1 WW domain-binding protein 1 BT1 PF03092.16 AIN98688.1 - 0.02 13.2 0.0 0.024 12.9 0.0 1.1 1 0 0 1 1 1 0 BT1 family DUF4381 PF14316.6 AIN98688.1 - 0.063 13.5 1.9 0.08 13.2 1.9 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4381) Cytadhesin_P30 PF07271.11 AIN98688.1 - 0.085 12.4 0.0 0.11 12.0 0.0 1.1 1 0 0 1 1 1 0 Cytadhesin P30/P32 EphA2_TM PF14575.6 AIN98689.1 - 0.018 15.9 0.1 0.021 15.7 0.1 1.1 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain SIT PF15330.6 AIN98689.1 - 0.043 14.3 0.1 0.054 13.9 0.1 1.1 1 0 0 1 1 1 0 SHP2-interacting transmembrane adaptor protein, SIT Pox_A21 PF05323.12 AIN98689.1 - 0.1 13.2 0.0 0.11 13.1 0.0 1.2 1 0 0 1 1 1 0 Poxvirus A21 Protein NopRA1 PF16201.5 AIN98692.1 - 1.6e-08 34.4 0.1 7.7e-08 32.2 0.1 2.3 1 1 0 1 1 1 1 Nucleolar pre-ribosomal-associated protein 1 Npa1 PF11707.8 AIN98692.1 - 5.9e-07 29.2 0.0 1.4e-06 27.9 0.0 1.6 1 0 0 1 1 1 1 Ribosome 60S biogenesis N-terminal MOR2-PAG1_N PF14222.6 AIN98692.1 - 0.035 13.1 0.1 0.081 11.9 0.1 1.5 1 0 0 1 1 1 0 Cell morphogenesis N-terminal Arm PF00514.23 AIN98692.1 - 0.31 11.2 2.8 1.7 8.8 0.7 3.6 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat SNF2_N PF00176.23 AIN98693.1 - 3.8e-34 118.0 0.0 5.8e-34 117.3 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 AIN98693.1 - 3.5e-10 40.2 0.0 1.1e-09 38.6 0.0 1.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 AIN98693.1 - 1.4e-07 31.6 0.0 2.7e-07 30.7 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit TniB PF05621.11 AIN98693.1 - 0.055 12.9 0.3 0.25 10.7 0.0 2.0 2 0 0 2 2 2 0 Bacterial TniB protein UCH PF00443.29 AIN98694.1 - 1.6e-44 152.4 0.0 2.3e-44 151.8 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 AIN98694.1 - 2.9e-10 40.3 0.3 3.6e-05 23.5 0.0 2.4 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase Kinesin PF00225.23 AIN98695.1 - 1.9e-90 303.2 0.0 2.5e-90 302.8 0.0 1.1 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 AIN98695.1 - 1.9e-17 63.6 0.0 3.7e-17 62.7 0.0 1.5 1 0 0 1 1 1 1 Microtubule binding Peptidase_C97 PF05903.14 AIN98696.1 - 3.2e-28 98.4 0.0 6e-28 97.6 0.0 1.4 1 0 0 1 1 1 1 PPPDE putative peptidase domain LRAT PF04970.13 AIN98696.1 - 0.009 16.3 0.5 0.022 15.1 0.0 1.8 2 0 0 2 2 2 1 Lecithin retinol acyltransferase HEAT_2 PF13646.6 AIN98697.1 - 0.0044 17.4 2.8 1.3 9.5 0.1 3.5 2 1 1 3 3 3 2 HEAT repeats Pkinase PF00069.25 AIN98698.1 - 4.7e-37 127.8 0.0 1.3e-36 126.4 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 AIN98698.1 - 2.2e-12 46.8 0.0 1.2e-11 44.5 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 AIN98698.1 - 0.065 12.6 0.0 0.11 11.8 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family TGFb_propeptide PF00688.18 AIN98698.1 - 0.12 12.1 0.0 0.2 11.4 0.0 1.2 1 0 0 1 1 1 0 TGF-beta propeptide Sugar_tr PF00083.24 AIN98699.1 - 4.5e-121 404.9 35.6 5.2e-121 404.7 35.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 AIN98699.1 - 8.9e-29 100.5 42.7 8.9e-29 100.5 42.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 AIN98699.1 - 0.00038 19.0 3.4 0.00038 19.0 3.4 1.7 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) DUF523 PF04463.12 AIN98701.1 - 5.9e-13 49.0 0.1 6e-07 29.6 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF523) zf-Tim10_DDP PF02953.15 AIN98702.1 - 0.00097 18.7 2.6 0.0014 18.3 2.6 1.4 1 1 0 1 1 1 1 Tim10/DDP family zinc finger SRP54 PF00448.22 AIN98703.1 - 1.1e-72 243.8 0.6 2.3e-72 242.7 0.6 1.6 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain SRP_SPB PF02978.19 AIN98703.1 - 5.6e-25 87.8 1.2 5.6e-25 87.8 1.2 4.3 4 1 0 4 4 4 1 Signal peptide binding domain SRP54_N PF02881.19 AIN98703.1 - 8e-14 51.6 4.7 8.1e-14 51.6 2.7 2.2 2 0 0 2 2 1 1 SRP54-type protein, helical bundle domain cobW PF02492.19 AIN98703.1 - 1.3e-05 24.8 0.2 4.9e-05 23.0 0.2 1.9 1 1 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain AAA_17 PF13207.6 AIN98703.1 - 9.1e-05 22.9 1.2 0.00022 21.7 0.1 2.1 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 AIN98703.1 - 9.9e-05 22.5 0.1 0.00026 21.2 0.0 1.8 2 0 0 2 2 1 1 AAA domain AAA_30 PF13604.6 AIN98703.1 - 0.00034 20.4 0.2 0.0011 18.7 0.2 1.9 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 AIN98703.1 - 0.00044 20.5 0.5 0.022 15.0 0.0 2.8 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.12 AIN98703.1 - 0.00094 18.5 0.0 0.0022 17.3 0.0 1.6 1 0 0 1 1 1 1 Zeta toxin MeaB PF03308.16 AIN98703.1 - 0.001 18.1 0.0 0.0036 16.3 0.0 1.8 1 1 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB GhoS PF11080.8 AIN98703.1 - 0.0017 18.3 0.2 4.3 7.4 0.1 3.3 4 0 0 4 4 3 1 Endoribonuclease GhoS AAA_16 PF13191.6 AIN98703.1 - 0.0021 18.5 0.6 0.0064 16.9 0.1 2.0 1 1 1 2 2 2 1 AAA ATPase domain CbiA PF01656.23 AIN98703.1 - 0.0039 17.2 0.0 0.01 15.9 0.0 2.1 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain Methyltransf_24 PF13578.6 AIN98703.1 - 0.0059 17.6 0.0 0.016 16.2 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain CLP1_P PF16575.5 AIN98703.1 - 0.011 15.5 0.1 1.4 8.6 0.0 2.6 2 0 0 2 2 2 0 mRNA cleavage and polyadenylation factor CLP1 P-loop APS_kinase PF01583.20 AIN98703.1 - 0.012 15.5 0.0 0.027 14.4 0.0 1.5 1 0 0 1 1 1 0 Adenylylsulphate kinase ATP_bind_1 PF03029.17 AIN98703.1 - 0.017 14.9 0.1 0.11 12.2 0.0 2.3 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein ResIII PF04851.15 AIN98703.1 - 0.027 14.5 0.6 2.2 8.3 0.1 2.4 1 1 1 2 2 2 0 Type III restriction enzyme, res subunit SRPRB PF09439.10 AIN98703.1 - 0.028 13.8 0.7 2.7 7.4 0.7 2.5 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_24 PF13479.6 AIN98703.1 - 0.032 13.9 0.4 0.11 12.2 0.1 2.0 2 0 0 2 2 2 0 AAA domain ATPase PF06745.13 AIN98703.1 - 0.037 13.4 0.3 0.38 10.0 0.0 2.4 2 0 0 2 2 2 0 KaiC MobB PF03205.14 AIN98703.1 - 0.053 13.4 0.1 0.25 11.2 0.0 2.2 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B SWI2_SNF2 PF18766.1 AIN98703.1 - 0.072 12.8 0.5 1.4 8.6 0.0 2.3 1 1 1 2 2 2 0 SWI2/SNF2 ATPase AAA_31 PF13614.6 AIN98703.1 - 0.075 12.9 1.1 2.4 8.0 0.0 2.8 2 1 1 3 3 2 0 AAA domain AAA_19 PF13245.6 AIN98703.1 - 0.1 12.9 0.6 0.3 11.4 0.1 2.0 2 0 0 2 2 2 0 AAA domain Dynamin_N PF00350.23 AIN98703.1 - 0.14 12.2 0.3 0.43 10.6 0.0 1.9 2 0 0 2 2 2 0 Dynamin family NTPase_1 PF03266.15 AIN98703.1 - 0.17 11.8 1.4 4.7 7.1 1.4 2.5 1 1 0 1 1 1 0 NTPase AAA PF00004.29 AIN98703.1 - 0.85 10.1 4.0 2.9 8.3 0.2 3.6 3 1 0 3 3 2 0 ATPase family associated with various cellular activities (AAA) HAD_SAK_2 PF18143.1 AIN98705.1 - 9.4e-33 113.5 0.2 9.6e-32 110.2 0.0 2.0 2 0 0 2 2 2 1 HAD domain in Swiss Army Knife RNA repair proteins CENP-F_leu_zip PF10473.9 AIN98705.1 - 0.023 14.7 1.9 0.023 14.7 1.9 1.9 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Val_tRNA-synt_C PF10458.9 AIN98705.1 - 0.058 13.7 6.4 0.44 10.9 0.1 2.9 3 0 0 3 3 3 0 Valyl tRNA synthetase tRNA binding arm SNF2_N PF00176.23 AIN98706.1 - 2.3e-57 194.3 0.0 3.8e-57 193.6 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 AIN98706.1 - 2.4e-16 60.0 0.0 7.9e-16 58.4 0.0 1.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 AIN98706.1 - 4.8e-10 39.7 0.0 8.9e-10 38.8 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 AIN98706.1 - 6.8e-08 32.5 0.0 1.3e-07 31.5 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase ERCC3_RAD25_C PF16203.5 AIN98706.1 - 1.3e-06 27.9 0.0 2.2e-06 27.1 0.0 1.3 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase Rad54_N PF08658.10 AIN98706.1 - 0.039 14.1 0.0 0.098 12.8 0.0 1.7 1 0 0 1 1 1 0 Rad54 N terminal Malic_M PF03949.15 AIN98707.1 - 8.5e-84 280.8 0.1 1.2e-83 280.4 0.1 1.2 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.19 AIN98707.1 - 9.3e-67 224.3 0.0 6.2e-66 221.7 0.0 2.0 2 0 0 2 2 2 1 Malic enzyme, N-terminal domain DUF3385 PF11865.8 AIN98707.1 - 0.065 13.1 0.0 0.12 12.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3385) Malic_M PF03949.15 AIN98708.1 - 2e-83 279.6 0.0 1e-82 277.3 0.0 1.9 2 0 0 2 2 2 1 Malic enzyme, NAD binding domain malic PF00390.19 AIN98708.1 - 3.6e-69 232.2 0.0 5.3e-69 231.7 0.0 1.2 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain Bac_luciferase PF00296.20 AIN98708.1 - 0.16 11.4 0.0 0.4 10.0 0.0 1.5 1 1 0 1 1 1 0 Luciferase-like monooxygenase 2-oxogl_dehyd_N PF16078.5 AIN98710.1 - 0.17 11.5 0.2 0.64 9.7 0.0 2.1 2 0 0 2 2 2 0 2-oxoglutarate dehydrogenase N-terminus PTS_2-RNA PF01885.16 AIN98712.1 - 6.4e-55 186.0 0.0 9.6e-55 185.4 0.0 1.2 1 0 0 1 1 1 1 RNA 2'-phosphotransferase, Tpt1 / KptA family RNase_T PF00929.24 AIN98712.1 - 8.7e-21 75.2 0.0 1.4e-20 74.5 0.0 1.4 1 0 0 1 1 1 1 Exonuclease Syja_N PF02383.18 AIN98713.1 - 4e-55 187.4 0.0 6.4e-55 186.7 0.0 1.2 1 0 0 1 1 1 1 SacI homology domain DUF547 PF04784.14 AIN98713.1 - 0.0028 17.7 0.0 0.0071 16.4 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function, DUF547 Ax_dynein_light PF10211.9 AIN98715.1 - 7.7e-79 264.0 6.4 9e-79 263.8 6.4 1.0 1 0 0 1 1 1 1 Axonemal dynein light chain Filament PF00038.21 AIN98715.1 - 0.00094 18.9 9.1 0.0021 17.7 3.4 2.0 1 1 1 2 2 2 1 Intermediate filament protein APG6_N PF17675.1 AIN98715.1 - 0.0012 19.4 10.5 0.0015 19.1 8.3 1.9 2 0 0 2 2 2 1 Apg6 coiled-coil region bZIP_1 PF00170.21 AIN98715.1 - 0.0031 17.6 4.5 0.011 15.8 1.5 2.3 2 0 0 2 2 2 1 bZIP transcription factor Jnk-SapK_ap_N PF09744.9 AIN98715.1 - 0.0043 17.3 9.9 0.016 15.5 5.6 2.1 2 0 0 2 2 2 1 JNK_SAPK-associated protein-1 Mei5 PF10376.9 AIN98715.1 - 0.024 14.5 1.9 0.037 13.9 1.9 1.4 1 0 0 1 1 1 0 Double-strand recombination repair protein HALZ PF02183.18 AIN98715.1 - 0.036 14.3 2.4 0.23 11.7 0.5 2.9 3 0 0 3 3 3 0 Homeobox associated leucine zipper Syntaxin-6_N PF09177.11 AIN98715.1 - 0.071 13.7 4.4 0.14 12.7 4.4 1.6 1 0 0 1 1 1 0 Syntaxin 6, N-terminal ERM PF00769.19 AIN98715.1 - 0.081 12.7 11.9 0.058 13.2 10.1 1.6 2 0 0 2 2 2 0 Ezrin/radixin/moesin family End3 PF12761.7 AIN98715.1 - 0.1 12.8 5.8 0.052 13.7 3.4 1.7 2 0 0 2 2 2 0 Actin cytoskeleton-regulatory complex protein END3 Spc24 PF08286.11 AIN98715.1 - 0.14 12.4 5.8 0.22 11.8 4.1 1.9 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 FapA PF03961.13 AIN98715.1 - 0.15 10.7 0.7 0.2 10.2 0.7 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A CENP-H PF05837.12 AIN98715.1 - 0.56 10.6 10.1 0.11 12.9 6.5 1.6 2 0 0 2 2 1 0 Centromere protein H (CENP-H) YabA PF06156.13 AIN98715.1 - 1.7 9.4 5.7 1.6 9.4 4.2 1.7 2 0 0 2 2 2 0 Initiation control protein YabA Prefoldin PF02996.17 AIN98715.1 - 2.8 7.9 8.3 5.8 6.9 0.3 2.6 2 1 1 3 3 3 0 Prefoldin subunit GIT_CC PF16559.5 AIN98715.1 - 7.5 6.5 7.1 2.7 7.9 2.4 2.2 2 0 0 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor TIM PF00121.18 AIN98716.1 - 1.7e-86 289.5 0.2 1.9e-86 289.4 0.2 1.0 1 0 0 1 1 1 1 Triosephosphate isomerase EMP24_GP25L PF01105.24 AIN98718.1 - 6.3e-17 62.1 0.0 7.6e-17 61.8 0.0 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD DUF779 PF05610.11 AIN98718.1 - 0.038 14.3 0.0 6.6 7.1 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF779) DUF5564 PF17719.1 AIN98718.1 - 0.14 12.3 0.0 0.23 11.6 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5564) DUF202 PF02656.15 AIN98718.1 - 0.67 10.4 3.4 5.7 7.5 0.2 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF202) DNA_pol_A PF00476.20 AIN98720.1 - 5.7e-54 183.6 0.0 2.3e-53 181.6 0.0 1.9 1 1 0 1 1 1 1 DNA polymerase family A MCM PF00493.23 AIN98722.1 - 4.1e-87 291.0 0.0 6.4e-87 290.3 0.0 1.3 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 AIN98722.1 - 3.4e-33 114.2 0.2 6.2e-33 113.3 0.2 1.4 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 AIN98722.1 - 1.3e-23 83.2 2.0 2.4e-23 82.3 0.7 2.2 2 1 0 2 2 2 1 MCM AAA-lid domain MCM_N PF14551.6 AIN98722.1 - 5e-10 39.9 0.0 1.5e-09 38.4 0.0 1.7 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 AIN98722.1 - 3.5e-07 29.8 0.0 6.6e-06 25.7 0.0 2.5 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 AIN98722.1 - 0.00029 20.7 0.0 0.001 19.0 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 AIN98722.1 - 0.00069 19.6 0.0 0.0016 18.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) PUA PF01472.20 AIN98722.1 - 0.016 15.2 1.3 3.7 7.6 0.2 2.7 2 0 0 2 2 2 0 PUA domain Sigma54_activat PF00158.26 AIN98722.1 - 0.056 13.1 0.0 0.15 11.8 0.0 1.7 1 0 0 1 1 1 0 Sigma-54 interaction domain MTS PF05175.14 AIN98723.1 - 0.002 17.7 0.0 0.04 13.5 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_25 PF13649.6 AIN98723.1 - 0.011 16.5 0.0 0.044 14.5 0.0 2.1 1 0 0 1 1 1 0 Methyltransferase domain EH_Signature PF15611.6 AIN98724.1 - 0.12 11.8 2.7 0.15 11.5 1.9 1.4 1 1 0 1 1 1 0 EH_Signature domain ANAPC4_WD40 PF12894.7 AIN98724.1 - 0.12 12.7 0.0 0.33 11.3 0.0 1.8 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 4 WD40 domain RabGAP-TBC PF00566.18 AIN98726.1 - 1e-09 38.4 2.4 3.3e-09 36.7 2.7 1.6 2 0 0 2 2 2 1 Rab-GTPase-TBC domain RFC1 PF08519.12 AIN98730.1 - 1.7e-41 142.0 0.0 3.6e-41 140.9 0.0 1.6 1 0 0 1 1 1 1 Replication factor RFC1 C terminal domain AAA PF00004.29 AIN98730.1 - 3.7e-12 46.8 0.0 1e-11 45.4 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 AIN98730.1 - 2.1e-08 34.3 0.0 3.8e-08 33.5 0.0 1.3 1 0 0 1 1 1 1 Rad17 P-loop domain Zeta_toxin PF06414.12 AIN98730.1 - 6.8e-05 22.2 0.0 0.0002 20.7 0.0 1.7 1 0 0 1 1 1 1 Zeta toxin AAA_22 PF13401.6 AIN98730.1 - 0.0005 20.4 0.0 0.0015 18.8 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.6 AIN98730.1 - 0.00077 19.5 0.0 0.0016 18.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.12 AIN98730.1 - 0.00099 18.9 0.0 0.0024 17.6 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 AIN98730.1 - 0.0014 19.1 0.1 0.0048 17.3 0.1 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.14 AIN98730.1 - 0.0027 17.7 0.0 0.0054 16.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_28 PF13521.6 AIN98730.1 - 0.003 17.8 0.5 0.33 11.2 0.0 2.4 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 AIN98730.1 - 0.027 14.9 0.0 0.077 13.4 0.0 1.8 1 0 0 1 1 1 0 RNA helicase AAA_33 PF13671.6 AIN98730.1 - 0.029 14.5 0.0 0.089 12.9 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 AIN98730.1 - 0.043 14.4 0.0 0.09 13.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 AIN98730.1 - 0.049 13.5 0.0 0.1 12.5 0.0 1.5 1 0 0 1 1 1 0 NTPase AAA_7 PF12775.7 AIN98730.1 - 0.063 12.8 0.0 0.17 11.4 0.0 1.7 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_assoc_2 PF16193.5 AIN98730.1 - 0.077 13.3 0.0 0.27 11.6 0.0 2.0 1 0 0 1 1 1 0 AAA C-terminal domain AAA_6 PF12774.7 AIN98730.1 - 0.086 11.8 0.0 0.14 11.1 0.0 1.2 1 0 0 1 1 1 0 Hydrolytic ATP binding site of dynein motor region AAA_19 PF13245.6 AIN98730.1 - 0.3 11.4 2.4 0.36 11.2 0.0 2.2 2 0 0 2 2 2 0 AAA domain DUF755 PF05501.11 AIN98730.1 - 4.6 7.5 28.5 8.8 6.6 25.4 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF755) Miga PF10265.9 AIN98730.1 - 8.7 5.2 12.9 14 4.5 12.9 1.3 1 0 0 1 1 1 0 Mitoguardin Mnd1 PF03962.15 AIN98732.1 - 2.6e-16 59.7 0.0 8.4e-16 58.0 0.0 1.8 2 0 0 2 2 2 1 Mnd1 HTH domain LZ3wCH PF18517.1 AIN98732.1 - 0.00014 21.9 0.0 0.00036 20.6 0.0 1.8 1 0 0 1 1 1 1 Leucine zipper with capping helix domain Kelch_6 PF13964.6 AIN98733.1 - 4.4e-15 55.4 1.9 0.00031 20.9 0.0 3.9 3 0 0 3 3 3 3 Kelch motif Kelch_4 PF13418.6 AIN98733.1 - 8.7e-13 48.1 0.1 9.2e-06 25.6 0.0 3.8 3 0 0 3 3 3 2 Galactose oxidase, central domain Kelch_1 PF01344.25 AIN98733.1 - 3e-09 36.3 6.5 0.00019 21.0 0.0 3.9 4 0 0 4 4 4 2 Kelch motif Kelch_5 PF13854.6 AIN98733.1 - 5.8e-09 35.7 0.1 0.0013 18.7 0.0 3.0 2 0 0 2 2 2 2 Kelch motif Kelch_3 PF13415.6 AIN98733.1 - 3.3e-05 24.0 0.9 1.5 9.2 0.3 3.9 3 0 0 3 3 3 2 Galactose oxidase, central domain F-box-like PF12937.7 AIN98733.1 - 4.2e-05 23.4 0.1 8.9e-05 22.3 0.1 1.5 1 0 0 1 1 1 1 F-box-like Kelch_2 PF07646.15 AIN98733.1 - 7e-05 22.6 0.0 0.075 13.0 0.0 3.6 3 0 0 3 3 3 1 Kelch motif F-box PF00646.33 AIN98733.1 - 0.00011 22.0 0.0 0.0003 20.6 0.0 1.7 1 0 0 1 1 1 1 F-box domain FAM75 PF14650.6 AIN98733.1 - 0.28 10.7 5.3 0.9 9.0 5.4 1.7 1 1 0 1 1 1 0 FAM75 family LRR_4 PF12799.7 AIN98734.1 - 6e-18 64.6 25.1 3.2e-07 30.5 1.8 3.6 2 1 3 5 5 5 4 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 AIN98734.1 - 6.4e-11 42.1 2.9 3e-09 36.6 0.8 2.1 1 1 1 2 2 2 2 Leucine-rich repeat LRR_8 PF13855.6 AIN98734.1 - 7.3e-10 38.5 7.8 1.2e-06 28.2 0.3 3.0 2 1 2 4 4 4 3 Leucine rich repeat FNIP PF05725.12 AIN98734.1 - 0.034 14.3 0.0 0.32 11.2 0.0 2.2 1 1 1 2 2 2 0 FNIP Repeat LRR_1 PF00560.33 AIN98734.1 - 0.15 12.7 6.2 12 6.9 1.0 3.5 2 2 0 2 2 2 0 Leucine Rich Repeat SNF2_N PF00176.23 AIN98736.1 - 4.5e-35 121.0 0.0 1.4e-34 119.3 0.0 1.7 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 AIN98736.1 - 8.9e-14 51.8 0.0 2.9e-12 46.9 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 AIN98736.1 - 0.0015 18.5 0.0 0.081 12.9 0.0 3.0 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit SWI2_SNF2 PF18766.1 AIN98736.1 - 0.015 15.0 0.1 0.046 13.4 0.0 1.8 2 0 0 2 2 2 0 SWI2/SNF2 ATPase CAMSAP_CC1 PF17095.5 AIN98736.1 - 0.14 12.0 5.6 0.39 10.6 5.6 1.8 1 0 0 1 1 1 0 Spectrin-binding region of Ca2+-Calmodulin AKAP7_NLS PF10469.9 AIN98737.1 - 9.3e-18 64.9 0.0 3e-17 63.2 0.0 1.7 1 1 0 1 1 1 1 AKAP7 2'5' RNA ligase-like domain C1_2 PF03107.16 AIN98737.1 - 0.03 14.6 1.0 0.094 13.0 0.4 2.0 2 0 0 2 2 2 0 C1 domain ADK_lid PF05191.14 AIN98737.1 - 0.051 13.6 0.0 2.2 8.3 0.0 2.9 2 0 0 2 2 2 0 Adenylate kinase, active site lid zinc_ribbon_2 PF13240.6 AIN98737.1 - 0.55 10.0 2.3 1.1 9.1 2.3 1.4 1 0 0 1 1 1 0 zinc-ribbon domain Hormone_3 PF00159.18 AIN98738.1 - 0.1 12.7 0.3 12 6.0 0.1 2.9 2 0 0 2 2 2 0 Pancreatic hormone peptide DnaJ PF00226.31 AIN98739.1 - 5e-14 52.2 0.1 2e-13 50.2 0.0 2.1 3 0 0 3 3 3 1 DnaJ domain HA2 PF04408.23 AIN98741.1 - 1.3e-12 47.9 0.0 5.7e-12 45.9 0.0 2.1 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 AIN98741.1 - 1.4e-10 41.4 0.0 3e-10 40.3 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 AIN98741.1 - 9.6e-10 38.8 0.1 2.7e-09 37.3 0.1 1.8 1 1 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 AIN98741.1 - 8.6e-06 25.6 0.1 1.8e-05 24.6 0.1 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_30 PF13604.6 AIN98741.1 - 0.0044 16.8 0.1 0.012 15.3 0.1 1.7 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 AIN98741.1 - 0.0045 17.3 0.7 0.034 14.4 0.7 2.3 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 AIN98741.1 - 0.0051 17.2 0.1 0.014 15.8 0.1 1.7 1 0 0 1 1 1 1 AAA domain ATPase PF06745.13 AIN98741.1 - 0.14 11.5 0.0 0.28 10.5 0.0 1.4 1 0 0 1 1 1 0 KaiC FH2 PF02181.23 AIN98742.1 - 5.4e-52 177.2 0.0 7.1e-52 176.7 0.0 1.1 1 0 0 1 1 1 1 Formin Homology 2 Domain PTEN_C2 PF10409.9 AIN98742.1 - 0.0034 17.1 0.1 0.0088 15.8 0.0 1.7 2 0 0 2 2 2 1 C2 domain of PTEN tumour-suppressor protein DUF1380 PF07128.12 AIN98742.1 - 0.082 13.1 0.5 0.33 11.1 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1380) Skp1_POZ PF03931.15 AIN98742.1 - 0.18 12.0 0.0 0.44 10.8 0.0 1.6 1 0 0 1 1 1 0 Skp1 family, tetramerisation domain SOAR PF16533.5 AIN98742.1 - 0.49 10.4 1.8 58 3.7 0.0 3.2 3 0 0 3 3 3 0 STIM1 Orai1-activating region APG6_N PF17675.1 AIN98745.1 - 0.0043 17.6 10.4 0.0043 17.6 10.4 6.6 5 1 1 6 6 6 2 Apg6 coiled-coil region CC2-LZ PF16516.5 AIN98745.1 - 0.016 15.6 7.1 0.016 15.6 7.1 8.0 5 2 2 7 7 7 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator DUF573 PF04504.14 AIN98745.1 - 6.3 7.5 7.4 0.86 10.3 0.8 3.1 2 1 1 3 3 3 0 Protein of unknown function, DUF573 HEPN_Toprim_N PF18871.1 AIN98745.1 - 8.8 6.2 11.2 1.6 8.6 2.3 3.2 2 1 2 4 4 4 0 HEPN/Toprim N-terminal domain 1 RNA_pol PF00940.19 AIN98747.1 - 2.9e-133 444.7 0.0 4.8e-133 444.0 0.0 1.4 1 0 0 1 1 1 1 DNA-dependent RNA polymerase Nore1-SARAH PF16517.5 AIN98748.1 - 1 9.4 4.4 20 5.2 0.1 2.8 2 0 0 2 2 2 0 Novel Ras effector 1 C-terminal SARAH (Sav/Rassf/Hpo) domain Syntaxin PF00804.25 AIN98748.1 - 3.5 7.2 14.0 0.21 11.2 1.3 2.5 2 0 0 2 2 2 0 Syntaxin TRAF_BIRC3_bd PF16673.5 AIN98748.1 - 4.8 7.0 7.7 9.7 6.1 3.1 2.9 2 0 0 2 2 2 0 TNF receptor-associated factor BIRC3 binding domain GTP-bdg_M PF16360.5 AIN98748.1 - 9 7.0 15.6 5.9 7.6 0.4 3.9 3 1 0 3 3 3 0 GTP-binding GTPase Middle Region Adaptin_binding PF10199.9 AIN98749.1 - 2.6e-05 24.8 0.0 0.048 14.3 0.0 3.2 3 1 0 3 3 3 2 Alpha and gamma adaptin binding protein p34 SURF6 PF04935.12 AIN98750.1 - 1.8e-17 63.8 2.4 1.8e-17 63.8 2.4 2.1 1 1 1 2 2 2 1 Surfeit locus protein 6 Phage-MuB_C PF09077.11 AIN98750.1 - 0.015 15.2 1.5 0.058 13.3 1.5 2.0 1 1 0 1 1 1 0 Mu B transposition protein, C terminal Bax1-I PF01027.20 AIN98751.1 - 2.4e-41 141.8 19.7 3.8e-41 141.2 19.7 1.3 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 BaxI_1 PF12811.7 AIN98751.1 - 1.1e-07 31.7 11.5 1.7e-07 31.0 11.5 1.4 1 1 0 1 1 1 1 Bax inhibitor 1 like YL1 PF05764.13 AIN98752.1 - 3.2e-10 40.5 17.3 3.2e-10 40.5 17.3 2.0 1 1 1 2 2 2 2 YL1 nuclear protein SUI1 PF01253.22 AIN98753.1 - 2.6e-21 75.9 0.2 3.3e-21 75.6 0.2 1.1 1 0 0 1 1 1 1 Translation initiation factor SUI1 DNA_processg_A PF02481.15 AIN98754.1 - 0.11 11.7 1.2 0.18 11.0 0.2 1.7 2 0 0 2 2 2 0 DNA recombination-mediator protein A PHD PF00628.29 AIN98755.1 - 1e-06 28.5 7.7 1e-06 28.5 7.7 1.7 2 0 0 2 2 2 1 PHD-finger Acetyltransf_7 PF13508.7 AIN98755.1 - 2.1e-05 24.9 0.0 4.4e-05 23.8 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain PHD_4 PF16866.5 AIN98755.1 - 0.0015 18.6 3.1 0.0015 18.6 3.1 2.3 2 0 0 2 2 2 1 PHD-finger Acetyltransf_10 PF13673.7 AIN98755.1 - 0.0048 16.8 0.2 0.52 10.3 0.2 2.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Amastin PF07344.11 AIN98757.1 - 1.9e-33 115.5 13.8 2.3e-33 115.2 13.8 1.0 1 0 0 1 1 1 1 Amastin surface glycoprotein WASH-7_mid PF14744.6 AIN98758.1 - 1.6e-127 425.4 0.9 2.7e-127 424.7 0.9 1.3 1 0 0 1 1 1 1 WASH complex subunit 7 WASH-7_C PF14746.6 AIN98758.1 - 3.4e-47 160.4 0.2 9.9e-47 158.9 0.2 1.9 1 0 0 1 1 1 1 WASH complex subunit 7, C-terminal WASH-7_N PF14745.6 AIN98758.1 - 2.4e-24 85.8 0.0 3.5e-14 52.2 0.0 2.3 2 0 0 2 2 2 2 WASH complex subunit 7, N-terminal DnaJ PF00226.31 AIN98759.1 - 2.3e-10 40.5 0.0 4.9e-10 39.4 0.0 1.5 1 0 0 1 1 1 1 DnaJ domain CCG PF02754.16 AIN98759.1 - 0.022 15.0 0.1 0.086 13.1 0.0 2.0 2 0 0 2 2 2 0 Cysteine-rich domain BLUF PF04940.12 AIN98760.1 - 0.023 14.8 0.0 0.061 13.5 0.0 1.7 1 0 0 1 1 1 0 Sensors of blue-light using FAD Pro_isomerase PF00160.21 AIN98761.1 - 2.4e-18 66.9 0.0 3.2e-18 66.5 0.0 1.2 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD TRAPP PF04051.16 AIN98762.1 - 2.1e-06 27.5 0.0 2.5e-06 27.3 0.0 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component GTP_EFTU PF00009.27 AIN98764.1 - 6.3e-24 84.6 1.1 5.1e-22 78.4 1.3 2.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 AIN98764.1 - 8.2e-12 45.2 0.0 2e-11 43.9 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase PduV-EutP PF10662.9 AIN98764.1 - 0.00011 21.9 0.0 0.00068 19.4 0.0 2.2 2 1 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation RsgA_GTPase PF03193.16 AIN98764.1 - 0.0011 19.0 0.1 0.097 12.6 0.4 2.7 2 0 0 2 2 2 1 RsgA GTPase IF-2 PF11987.8 AIN98764.1 - 0.0011 19.0 0.0 0.0027 17.8 0.0 1.6 1 0 0 1 1 1 1 Translation-initiation factor 2 Dynamin_N PF00350.23 AIN98764.1 - 0.006 16.6 0.9 0.14 12.2 0.0 3.0 2 1 1 3 3 3 1 Dynamin family Roc PF08477.13 AIN98764.1 - 0.01 16.0 0.0 0.031 14.5 0.0 1.8 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase cobW PF02492.19 AIN98764.1 - 0.017 14.7 3.1 0.1 12.2 0.5 3.0 2 1 1 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain FeoB_N PF02421.18 AIN98764.1 - 0.033 13.7 0.2 0.13 11.7 0.2 2.0 1 1 0 1 1 1 0 Ferrous iron transport protein B DUF1484 PF07363.11 AIN98764.1 - 0.039 15.0 0.2 0.1 13.6 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1484) TniB PF05621.11 AIN98764.1 - 0.08 12.3 0.0 0.21 11.0 0.0 1.6 2 0 0 2 2 2 0 Bacterial TniB protein APO_RNA-bind PF05634.11 AIN98764.1 - 0.12 11.7 1.3 7.4 5.9 0.1 2.8 3 0 0 3 3 3 0 APO RNA-binding IQ PF00612.27 AIN98765.1 - 3.9e-06 26.2 38.7 0.019 14.7 0.3 7.0 6 1 0 6 6 6 5 IQ calmodulin-binding motif HTH_37 PF13744.6 AIN98765.1 - 0.52 10.3 3.3 0.97 9.4 0.4 2.9 3 0 0 3 3 3 0 Helix-turn-helix domain Dymeclin PF09742.9 AIN98766.1 - 6.9e-56 189.9 0.0 8.7e-56 189.6 0.0 1.1 1 0 0 1 1 1 1 Dyggve-Melchior-Clausen syndrome protein Hid1 PF12722.7 AIN98766.1 - 2.5e-27 95.5 4.5 6.7e-15 54.3 2.6 4.2 4 1 0 4 4 4 3 High-temperature-induced dauer-formation protein Hist_deacetyl PF00850.19 AIN98767.1 - 4.8e-72 243.0 0.1 5.8e-72 242.8 0.1 1.1 1 0 0 1 1 1 1 Histone deacetylase domain EF-hand_7 PF13499.6 AIN98768.1 - 4.2e-22 78.4 5.6 6.7e-13 48.9 0.4 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 AIN98768.1 - 7.3e-19 66.0 5.2 0.00088 19.0 0.1 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_1 PF00036.32 AIN98768.1 - 8e-19 65.7 6.8 0.0001 21.6 0.1 4.3 4 0 0 4 4 4 4 EF hand EF-hand_5 PF13202.6 AIN98768.1 - 5.1e-14 51.0 8.4 6.6e-05 22.2 0.1 4.3 4 0 0 4 4 4 4 EF hand zf-C3HC4_3 PF13920.6 AIN98768.1 - 4.2e-11 42.5 6.3 4.2e-11 42.5 6.3 1.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) EF-hand_8 PF13833.6 AIN98768.1 - 1.5e-09 37.6 6.0 0.0016 18.2 0.2 3.5 3 1 0 3 3 3 3 EF-hand domain pair zf-C3HC4_2 PF13923.6 AIN98768.1 - 2.3e-09 37.0 10.1 4.9e-09 35.9 10.1 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 AIN98768.1 - 3.3e-08 33.4 2.7 3.3e-08 33.4 2.7 2.5 2 0 0 2 2 2 1 RING-type zinc-finger Prok-RING_4 PF14447.6 AIN98768.1 - 4.2e-08 32.9 7.5 1.3e-07 31.4 7.6 1.7 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 AIN98768.1 - 5.3e-08 32.7 7.2 5.3e-08 32.7 7.2 1.7 2 0 0 2 2 1 1 zinc-RING finger domain zf-RING_2 PF13639.6 AIN98768.1 - 1.7e-06 28.3 8.8 1.7e-06 28.3 8.8 1.8 2 0 0 2 2 1 1 Ring finger domain zf-C3HC4 PF00097.25 AIN98768.1 - 2.9e-06 27.0 9.1 2.9e-06 27.0 9.1 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) SPARC_Ca_bdg PF10591.9 AIN98768.1 - 3.6e-06 27.3 0.0 0.001 19.3 0.0 2.4 2 0 0 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region zf-RING_6 PF14835.6 AIN98768.1 - 0.00013 21.8 4.1 0.00028 20.7 4.1 1.5 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-C3HC4_4 PF15227.6 AIN98768.1 - 0.0011 19.1 4.8 0.0011 19.1 4.8 2.5 2 1 1 3 3 3 1 zinc finger of C3HC4-type, RING zf-RING_11 PF17123.5 AIN98768.1 - 0.06 13.1 6.4 0.038 13.7 3.3 2.2 2 0 0 2 2 2 0 RING-like zinc finger EF-hand_10 PF14788.6 AIN98768.1 - 0.1 12.5 0.3 50 3.9 0.0 3.4 3 1 1 4 4 4 0 EF hand zf-RING_10 PF16685.5 AIN98768.1 - 2.2 8.4 10.9 7.5 6.8 10.8 1.9 1 1 1 2 2 2 0 zinc RING finger of MSL2 DZR PF12773.7 AIN98768.1 - 7.4 6.7 13.2 86 3.3 12.4 2.5 1 1 0 1 1 1 0 Double zinc ribbon BicD PF09730.9 AIN98769.1 - 0.022 13.2 14.5 0.36 9.2 8.1 2.0 1 1 1 2 2 2 0 Microtubule-associated protein Bicaudal-D Atg14 PF10186.9 AIN98769.1 - 0.039 13.0 10.8 0.054 12.6 10.8 1.4 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 SlyX PF04102.12 AIN98769.1 - 0.7 10.5 15.0 4.9 7.9 2.4 3.5 2 1 0 3 3 3 0 SlyX TMF_TATA_bd PF12325.8 AIN98769.1 - 0.77 10.0 16.7 1.4 9.1 12.7 2.3 1 1 0 2 2 2 0 TATA element modulatory factor 1 TATA binding DUF16 PF01519.16 AIN98769.1 - 1.1 9.8 9.5 2.8 8.5 5.5 2.7 1 1 2 3 3 3 0 Protein of unknown function DUF16 DUF641 PF04859.12 AIN98769.1 - 1.7 9.0 15.8 0.83 10.0 7.8 2.8 1 1 2 3 3 3 0 Plant protein of unknown function (DUF641) UPF0242 PF06785.11 AIN98769.1 - 2.4 8.2 17.1 7.5 6.6 17.1 1.7 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus ATG16 PF08614.11 AIN98769.1 - 6.1 7.0 27.4 6.9 6.8 14.5 3.0 1 1 2 3 3 3 0 Autophagy protein 16 (ATG16) V_ATPase_I PF01496.19 AIN98769.1 - 6.3 4.6 6.3 7.2 4.4 6.3 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family LMBR1 PF04791.16 AIN98769.1 - 8.9 5.1 5.3 10 4.9 5.3 1.0 1 0 0 1 1 1 0 LMBR1-like membrane protein Viral_helicase1 PF01443.18 AIN98770.1 - 0.15 11.7 0.0 0.29 10.8 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase Insulin_TMD PF17870.1 AIN98770.1 - 0.18 11.9 0.9 0.36 10.9 0.9 1.5 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment Mlh1_C PF16413.5 AIN98771.1 - 1.2e-31 110.1 0.0 2.8e-11 43.3 0.0 3.2 3 0 0 3 3 3 3 DNA mismatch repair protein Mlh1 C-terminus DNA_mis_repair PF01119.19 AIN98771.1 - 2.2e-23 82.2 0.0 4.5e-23 81.2 0.0 1.4 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.6 AIN98771.1 - 2.5e-10 40.3 0.1 2.1e-09 37.3 0.0 2.1 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 AIN98771.1 - 3.7e-05 24.2 0.0 8.1e-05 23.1 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Kinesin PF00225.23 AIN98772.1 - 1.2e-55 188.8 0.0 6.1e-39 133.9 0.0 2.2 2 0 0 2 2 2 2 Kinesin motor domain Microtub_bd PF16796.5 AIN98772.1 - 4.5e-11 42.9 0.0 8.7e-11 42.0 0.0 1.3 1 0 0 1 1 1 1 Microtubule binding HpcH_HpaI PF03328.14 AIN98774.1 - 1.8e-20 73.0 0.0 2.1e-17 63.0 0.0 2.8 1 1 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family C-C_Bond_Lyase PF15617.6 AIN98774.1 - 2.5e-13 49.9 0.0 6.5e-07 28.8 0.1 2.1 2 0 0 2 2 2 2 C-C_Bond_Lyase of the TIM-Barrel fold Pkinase PF00069.25 AIN98775.1 - 9.9e-65 218.5 0.0 1.3e-64 218.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 AIN98775.1 - 6.5e-41 140.3 0.0 9.5e-41 139.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 AIN98775.1 - 1.2e-05 24.2 0.4 1.9e-05 23.6 0.0 1.4 2 0 0 2 2 2 1 Fungal protein kinase Kdo PF06293.14 AIN98775.1 - 2.9e-05 23.5 0.0 0.00016 21.1 0.0 2.0 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 AIN98775.1 - 0.0077 15.9 0.0 0.013 15.2 0.0 1.3 1 0 0 1 1 1 1 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 AIN98775.1 - 0.01 15.7 0.1 0.33 10.9 0.1 2.7 1 1 2 3 3 3 0 Phosphotransferase enzyme family Haspin_kinase PF12330.8 AIN98775.1 - 0.23 10.4 0.0 0.49 9.3 0.0 1.4 1 1 0 1 1 1 0 Haspin like kinase domain WD40 PF00400.32 AIN98777.1 - 0.018 15.9 0.0 40 5.3 0.0 4.9 4 0 0 4 4 4 0 WD domain, G-beta repeat PGA2 PF07543.12 AIN98777.1 - 0.2 11.7 0.4 7.4 6.6 0.1 2.4 2 0 0 2 2 2 0 Protein trafficking PGA2 START PF01852.19 AIN98778.1 - 0.0099 15.3 0.0 0.95 8.8 0.0 2.9 3 0 0 3 3 3 1 START domain CALM_bind PF16025.5 AIN98778.1 - 0.077 13.5 0.2 0.19 12.2 0.2 1.7 1 0 0 1 1 1 0 Calcium-dependent calmodulin binding WD40 PF00400.32 AIN98779.1 - 6.4e-08 33.1 4.1 0.0028 18.4 0.2 4.9 4 0 0 4 4 4 3 WD domain, G-beta repeat TCTP PF00838.17 AIN98780.1 - 1.1e-44 152.7 1.4 1.2e-44 152.6 1.4 1.0 1 0 0 1 1 1 1 Translationally controlled tumour protein UPF0262 PF06793.12 AIN98780.1 - 0.053 13.6 0.2 0.071 13.2 0.2 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0262) DUF932 PF06067.11 AIN98780.1 - 0.054 13.3 0.4 0.082 12.7 0.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF932) RICH PF05062.12 AIN98780.1 - 0.055 13.8 0.4 0.11 12.9 0.4 1.4 1 0 0 1 1 1 0 RICH domain DUF273 PF03314.14 AIN98780.1 - 0.092 12.3 0.3 2.2 7.8 0.3 2.0 1 1 1 2 2 2 0 Protein of unknown function, DUF273 ERCC4 PF02732.15 AIN98781.1 - 3.9e-09 36.9 0.0 7.6e-09 36.0 0.0 1.5 1 0 0 1 1 1 1 ERCC4 domain SAP PF02037.27 AIN98781.1 - 9.8e-05 22.0 0.3 9.8e-05 22.0 0.3 2.0 2 0 0 2 2 2 1 SAP domain RecQ_Zn_bind PF16124.5 AIN98782.1 - 7e-16 58.7 0.1 2.1e-15 57.2 0.1 1.9 1 0 0 1 1 1 1 RecQ zinc-binding DEAD PF00270.29 AIN98782.1 - 3e-15 56.4 0.0 1.3e-14 54.3 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 AIN98782.1 - 1.2e-13 51.4 0.0 4.2e-12 46.4 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain HRDC PF00570.23 AIN98782.1 - 1.6e-05 24.8 0.0 3.3e-05 23.8 0.0 1.5 1 0 0 1 1 1 1 HRDC domain Choline_kin_N PF04428.14 AIN98782.1 - 0.062 13.0 0.0 0.16 11.7 0.0 1.6 1 0 0 1 1 1 0 Choline kinase N terminus Clat_adaptor_s PF01217.20 AIN98783.1 - 1.4e-44 151.5 0.8 1.6e-44 151.3 0.8 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain MRG PF05712.13 AIN98783.1 - 0.053 12.8 0.0 0.054 12.8 0.0 1.2 1 0 0 1 1 1 0 MRG LRR_6 PF13516.6 AIN98785.1 - 0.001 18.9 1.4 2 8.6 0.0 3.4 3 0 0 3 3 3 2 Leucine Rich repeat EF-hand_6 PF13405.6 AIN98785.1 - 0.032 14.2 0.1 10 6.4 0.0 3.2 3 0 0 3 3 3 0 EF-hand domain EF-hand_1 PF00036.32 AIN98785.1 - 0.13 11.9 1.3 13 5.6 0.1 3.0 3 0 0 3 3 3 0 EF hand RRM_1 PF00076.22 AIN98786.1 - 1.6e-32 111.2 1.2 3.4e-21 74.8 0.0 3.4 2 1 1 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 AIN98786.1 - 2e-05 24.5 0.0 0.035 14.1 0.0 2.5 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif RRM_5 PF13893.6 AIN98786.1 - 0.00034 20.2 0.0 0.0017 17.9 0.0 2.2 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 AIN98786.1 - 0.001 19.2 0.0 0.57 10.3 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif PHM7_cyt PF14703.6 AIN98786.1 - 0.0014 18.9 0.6 2.3 8.4 0.0 3.2 2 2 1 3 3 3 2 Cytosolic domain of 10TM putative phosphate transporter Limkain-b1 PF11608.8 AIN98786.1 - 0.011 15.8 0.0 0.033 14.3 0.0 1.8 1 0 0 1 1 1 0 Limkain b1 Rhomboid PF01694.22 AIN98787.1 - 0.013 15.5 1.2 0.026 14.5 1.2 1.5 1 0 0 1 1 1 0 Rhomboid family UBA PF00627.31 AIN98787.1 - 0.056 13.4 0.3 0.1 12.5 0.3 1.5 1 0 0 1 1 1 0 UBA/TS-N domain DNA_Packaging PF11053.8 AIN98789.1 - 0.22 11.4 1.7 4.9 7.0 0.3 2.0 2 0 0 2 2 2 0 Terminase DNA packaging enzyme zf-rbx1 PF12678.7 AIN98790.1 - 1.3e-20 73.5 12.9 1.8e-20 73.0 12.9 1.2 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 AIN98790.1 - 5.2e-12 45.7 10.0 7.1e-12 45.2 9.4 1.5 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_2 PF13639.6 AIN98790.1 - 1.5e-09 38.0 5.7 1.5e-09 38.0 5.7 2.2 1 1 1 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.25 AIN98790.1 - 3.4e-06 26.8 11.0 5.2e-05 23.0 11.0 2.2 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 AIN98790.1 - 0.00017 21.4 8.2 0.00017 21.4 8.2 2.4 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 AIN98790.1 - 0.00033 20.5 3.6 0.00033 20.5 3.6 2.2 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 AIN98790.1 - 0.00046 19.8 15.5 0.028 14.0 2.1 2.2 1 1 1 2 2 2 2 Zinc-ribbon, C4HC2 type zf-RING_11 PF17123.5 AIN98790.1 - 0.0015 18.2 13.1 0.32 10.8 13.1 2.4 1 1 0 1 1 1 1 RING-like zinc finger FANCL_C PF11793.8 AIN98790.1 - 0.058 13.6 10.0 0.12 12.6 10.0 1.5 1 1 0 1 1 1 0 FANCL C-terminal domain zf-RING_UBOX PF13445.6 AIN98790.1 - 0.13 12.3 13.7 0.76 9.9 13.7 2.1 1 1 0 1 1 1 0 RING-type zinc-finger zf-RING_5 PF14634.6 AIN98790.1 - 0.14 12.1 12.2 0.95 9.5 12.2 2.0 1 1 0 1 1 1 0 zinc-RING finger domain GST_N_4 PF17172.4 AIN98791.1 - 1.6e-14 54.4 0.0 3.4e-14 53.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase N-terminal domain Tom37 PF10568.9 AIN98791.1 - 3e-07 30.8 0.0 6.7e-07 29.7 0.0 1.6 1 0 0 1 1 1 1 Outer mitochondrial membrane transport complex protein GST_C_6 PF17171.4 AIN98791.1 - 3.5e-06 26.7 0.2 3.1e-05 23.7 0.1 2.4 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 AIN98791.1 - 0.0016 18.4 0.0 0.004 17.1 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain PfaD_N PF18328.1 AIN98791.1 - 0.059 13.3 0.0 0.12 12.3 0.0 1.4 1 0 0 1 1 1 0 Fatty acid synthase subunit PfaD N-terminal domain FAD_binding_2 PF00890.24 AIN98792.1 - 4.7e-117 391.6 3.0 3.9e-116 388.6 1.6 2.0 2 0 0 2 2 2 1 FAD binding domain Succ_DH_flav_C PF02910.20 AIN98792.1 - 2.3e-41 140.8 0.9 3.2e-41 140.3 0.9 1.2 1 0 0 1 1 1 1 Fumarate reductase flavoprotein C-term Pyr_redox_2 PF07992.14 AIN98792.1 - 0.00035 19.9 0.1 0.00094 18.5 0.1 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 AIN98792.1 - 0.0013 18.0 0.1 0.17 11.1 0.1 2.3 2 0 0 2 2 2 2 Thi4 family DAO PF01266.24 AIN98792.1 - 0.0024 17.5 0.3 0.024 14.2 0.3 2.1 1 1 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.14 AIN98792.1 - 0.025 13.3 0.1 0.044 12.5 0.1 1.3 1 0 0 1 1 1 0 HI0933-like protein GIDA PF01134.22 AIN98792.1 - 0.049 12.7 3.3 0.11 11.5 2.4 1.8 2 0 0 2 2 2 0 Glucose inhibited division protein A Lycopene_cycl PF05834.12 AIN98792.1 - 0.1 11.6 1.6 1.7 7.6 0.5 2.2 2 0 0 2 2 2 0 Lycopene cyclase protein FAD_binding_3 PF01494.19 AIN98792.1 - 0.13 11.5 2.5 0.62 9.2 0.3 2.3 2 0 0 2 2 2 0 FAD binding domain NAD_binding_4 PF07993.12 AIN98793.1 - 1.2e-65 221.3 0.0 1.6e-65 220.8 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein Sterile PF03015.19 AIN98793.1 - 1.1e-11 44.8 0.1 2.4e-11 43.7 0.1 1.6 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.21 AIN98793.1 - 1.6e-05 24.5 0.1 8e-05 22.2 0.1 2.1 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 AIN98793.1 - 0.0015 17.7 0.0 0.079 12.0 0.0 2.8 3 0 0 3 3 3 1 RmlD substrate binding domain GDP_Man_Dehyd PF16363.5 AIN98793.1 - 0.0064 15.9 0.1 0.38 10.1 0.0 2.2 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 AIN98793.1 - 0.027 13.6 0.0 5 6.2 0.0 2.4 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein Semialdhyde_dh PF01118.24 AIN98793.1 - 0.059 13.8 0.0 0.12 12.8 0.0 1.5 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain DUF4515 PF14988.6 AIN98794.1 - 0.72 9.7 47.2 0.45 10.3 6.0 3.2 1 1 1 3 3 3 0 Domain of unknown function (DUF4515) MCC-bdg_PDZ PF10506.9 AIN98794.1 - 2.8 8.0 9.9 7.4 6.7 0.3 3.9 3 1 1 4 4 4 0 PDZ domain of MCC-2 bdg protein for Usher syndrome TMF_TATA_bd PF12325.8 AIN98794.1 - 3.1 8.1 41.0 0.07 13.3 9.7 4.6 1 1 3 4 4 4 0 TATA element modulatory factor 1 TATA binding SpoU_methylase PF00588.19 AIN98795.1 - 6.7e-15 55.5 0.0 5e-13 49.4 0.0 2.7 2 1 0 2 2 2 1 SpoU rRNA Methylase family Ssl1 PF04056.14 AIN98797.1 - 1.1e-17 64.4 0.1 3.3e-08 33.6 0.0 2.2 1 1 0 2 2 2 2 Ssl1-like VWA_2 PF13519.6 AIN98797.1 - 1.5e-08 35.2 0.0 3e-08 34.3 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain Rubredoxin_2 PF18073.1 AIN98797.1 - 0.04 13.6 7.6 1.1 9.0 0.5 3.4 3 0 0 3 3 3 0 Rubredoxin metal binding domain EBV-NA3 PF05009.12 AIN98797.1 - 0.042 13.4 0.0 0.065 12.8 0.0 1.2 1 0 0 1 1 1 0 Epstein-Barr virus nuclear antigen 3 (EBNA-3) Nup153 PF08604.10 AIN98797.1 - 0.082 11.7 0.3 0.12 11.1 0.3 1.3 1 0 0 1 1 1 0 Nucleoporin Nup153-like C1_4 PF07975.12 AIN98797.1 - 0.15 12.3 4.8 1.4 9.2 0.7 3.5 3 0 0 3 3 3 0 TFIIH C1-like domain DZR PF12773.7 AIN98797.1 - 2.4 8.3 10.5 6.3e+02 0.5 10.5 2.6 1 1 0 1 1 1 0 Double zinc ribbon SET PF00856.28 AIN98798.1 - 5.8e-10 39.8 0.2 1.1e-09 38.9 0.2 1.5 1 1 0 1 1 1 1 SET domain TPR_1 PF00515.28 AIN98798.1 - 0.0012 18.6 0.8 0.0012 18.6 0.8 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat zf-tcix PF14952.6 AIN98798.1 - 0.0063 16.1 1.3 0.0063 16.1 1.3 2.6 4 0 0 4 4 4 1 Putative treble-clef, zinc-finger, Zn-binding TPR_2 PF07719.17 AIN98798.1 - 0.034 14.3 3.4 0.05 13.7 0.4 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat Ribosomal_S21 PF01165.20 AIN98799.1 - 2.4 7.9 5.5 0.47 10.2 0.6 2.2 2 0 0 2 2 2 0 Ribosomal protein S21 UQ_con PF00179.26 AIN98800.1 - 2e-18 66.4 0.0 2.7e-18 66.0 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 AIN98800.1 - 0.033 13.9 0.0 0.047 13.4 0.0 1.4 1 1 0 1 1 1 0 Prokaryotic E2 family B WD40 PF00400.32 AIN98801.1 - 1.1e-26 92.5 17.1 3.6e-06 27.6 0.0 7.0 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 AIN98801.1 - 1.9e-20 73.0 2.3 1.6e-07 31.6 0.1 5.6 2 1 4 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 AIN98801.1 - 5.7e-07 29.6 0.0 0.09 12.6 0.0 3.0 2 1 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 AIN98801.1 - 0.00039 19.5 0.2 0.57 9.1 0.0 3.0 3 0 0 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein IKI3 PF04762.12 AIN98801.1 - 0.033 12.2 0.8 0.52 8.2 0.0 2.4 2 1 0 2 2 2 0 IKI3 family Nbas_N PF15492.6 AIN98801.1 - 0.042 13.2 0.3 4.6 6.5 0.0 3.1 1 1 2 3 3 3 0 Neuroblastoma-amplified sequence, N terminal Pkinase PF00069.25 AIN98802.1 - 1.4e-46 159.0 0.0 2.3e-46 158.3 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 AIN98802.1 - 3.4e-27 95.4 0.0 7.8e-27 94.2 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase LRR_8 PF13855.6 AIN98802.1 - 5.3e-07 29.3 2.6 0.00013 21.7 0.0 3.3 3 0 0 3 3 3 1 Leucine rich repeat Kinase-like PF14531.6 AIN98802.1 - 1.5e-05 24.5 0.1 0.0027 17.1 0.0 2.3 2 0 0 2 2 2 2 Kinase-like LRR_4 PF12799.7 AIN98802.1 - 4.1e-05 23.9 0.8 0.6 10.6 0.0 3.7 3 1 0 3 3 3 1 Leucine Rich repeats (2 copies) zf-B_box PF00643.24 AIN98802.1 - 0.0044 17.2 2.9 0.0044 17.2 2.9 3.1 3 0 0 3 3 2 2 B-box zinc finger zf-UBR PF02207.20 AIN98802.1 - 0.0089 16.2 1.3 0.0089 16.2 1.3 3.2 3 0 0 3 3 2 1 Putative zinc finger in N-recognin (UBR box) LRR_1 PF00560.33 AIN98802.1 - 0.075 13.6 0.1 34 5.5 0.0 3.5 2 0 0 2 2 2 0 Leucine Rich Repeat APH PF01636.23 AIN98802.1 - 0.087 12.7 0.2 0.42 10.5 0.1 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family ZZ PF00569.17 AIN98802.1 - 0.24 11.2 22.8 0.9 9.4 6.8 2.7 2 0 0 2 2 2 0 Zinc finger, ZZ type zf-H2C2_5 PF13909.6 AIN98802.1 - 0.55 10.0 2.6 1.6 8.6 2.6 1.9 1 0 0 1 1 1 0 C2H2-type zinc-finger domain C1_2 PF03107.16 AIN98802.1 - 4.4 7.7 33.7 0.11 12.8 11.8 2.9 3 0 0 3 3 2 0 C1 domain zf-C3HC4_3 PF13920.6 AIN98802.1 - 5 7.1 15.9 1.6 8.6 3.8 2.9 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) GCV_T PF01571.21 AIN98803.1 - 4.5e-08 32.8 0.0 6.7e-08 32.2 0.0 1.2 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain Propep_M14 PF02244.16 AIN98803.1 - 0.079 13.4 0.1 0.22 11.9 0.1 1.7 1 0 0 1 1 1 0 Carboxypeptidase activation peptide SUZ PF12752.7 AIN98803.1 - 0.26 12.1 2.0 0.78 10.5 2.0 1.8 1 0 0 1 1 1 0 SUZ domain SET PF00856.28 AIN98804.1 - 1.4e-10 41.9 0.0 1.6e-08 35.1 0.0 2.3 2 0 0 2 2 2 2 SET domain CGI-121 PF08617.10 AIN98805.1 - 7.6e-05 22.9 0.0 0.00014 22.0 0.0 1.6 1 1 0 1 1 1 1 Kinase binding protein CGI-121 Cyclin_C_2 PF16899.5 AIN98805.1 - 0.14 12.6 0.5 0.29 11.5 0.5 1.8 1 1 0 1 1 1 0 Cyclin C-terminal domain Inhibitor_I42 PF09394.10 AIN98806.1 - 5.8e-17 61.9 0.1 6.8e-17 61.7 0.1 1.1 1 0 0 1 1 1 1 Chagasin family peptidase inhibitor I42 CzcE PF16986.5 AIN98806.1 - 0.086 13.2 0.1 0.25 11.7 0.0 1.7 2 0 0 2 2 2 0 Heavy-metal resistance protein CzcE AMP-binding PF00501.28 AIN98807.1 - 3.8e-14 52.1 4.7 0.00053 18.7 0.0 4.9 4 1 0 4 4 4 4 AMP-binding enzyme DUF620 PF04788.12 AIN98807.1 - 0.065 12.7 0.0 12 5.2 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF620) RRM_1 PF00076.22 AIN98808.1 - 1.5e-16 59.9 0.0 4.8e-16 58.3 0.0 1.8 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TFIIA PF03153.13 AIN98808.1 - 0.052 13.5 16.5 0.063 13.3 16.5 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit RRM_5 PF13893.6 AIN98808.1 - 0.057 13.0 0.1 0.39 10.3 0.0 2.1 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM PF05172.13 AIN98808.1 - 0.16 12.0 0.0 0.47 10.4 0.0 1.8 1 1 0 1 1 1 0 Nup53/35/40-type RNA recognition motif PAT1 PF09770.9 AIN98808.1 - 6.2 5.0 13.7 7.4 4.7 13.7 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF2076 PF09849.9 AIN98808.1 - 8.2 6.4 24.3 11 6.0 24.3 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) Lin-8 PF03353.15 AIN98808.1 - 9.1 5.7 8.3 13 5.2 8.3 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Mannitol_dh_C PF08125.13 AIN98809.1 - 0.16 11.4 0.0 0.2 11.1 0.0 1.2 1 0 0 1 1 1 0 Mannitol dehydrogenase C-terminal domain adh_short PF00106.25 AIN98810.1 - 3.8e-20 72.2 0.5 9.1e-20 70.9 0.5 1.6 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 AIN98810.1 - 3.5e-11 43.1 2.4 5.3e-11 42.5 0.5 2.1 3 0 0 3 3 3 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 AIN98810.1 - 4.1e-07 30.1 0.4 1e-06 28.8 0.4 1.6 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 AIN98810.1 - 0.00061 19.3 0.5 0.0011 18.5 0.5 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_7 PF13241.6 AIN98810.1 - 0.0073 16.7 0.2 0.019 15.4 0.1 1.8 2 0 0 2 2 2 1 Putative NAD(P)-binding THF_DHG_CYH_C PF02882.19 AIN98810.1 - 0.011 15.0 0.2 0.35 10.2 0.0 2.8 3 0 0 3 3 3 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain ApbA PF02558.16 AIN98810.1 - 0.03 14.0 0.1 0.052 13.2 0.1 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA LSDAT_euk PF18139.1 AIN98810.1 - 0.035 13.5 0.0 0.056 12.8 0.0 1.2 1 0 0 1 1 1 0 SLOG in TRPM ArsA_ATPase PF02374.15 AIN98810.1 - 0.041 13.1 0.0 0.057 12.6 0.0 1.1 1 0 0 1 1 1 0 Anion-transporting ATPase GDP_Man_Dehyd PF16363.5 AIN98810.1 - 0.045 13.1 0.0 0.071 12.5 0.0 1.3 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase DFP PF04127.15 AIN98810.1 - 0.067 13.0 1.2 1.3 8.8 0.4 2.5 2 1 0 2 2 2 0 DNA / pantothenate metabolism flavoprotein LEA_3 PF03242.13 AIN98810.1 - 0.37 11.5 2.7 1.1 10.0 2.7 1.8 1 0 0 1 1 1 0 Late embryogenesis abundant protein DUF3035 PF11233.8 AIN98810.1 - 0.53 10.6 1.8 1.1 9.5 1.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3035) adh_short PF00106.25 AIN98811.1 - 2.7e-22 79.2 0.0 1e-12 48.0 0.0 3.2 2 1 1 3 3 3 2 short chain dehydrogenase adh_short_C2 PF13561.6 AIN98811.1 - 4.6e-11 42.7 0.0 1.2e-06 28.3 0.0 2.3 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 AIN98811.1 - 3.7e-06 27.0 0.0 7.1e-06 26.0 0.0 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 AIN98811.1 - 0.0011 18.5 0.0 0.0027 17.2 0.0 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_7 PF13241.6 AIN98811.1 - 0.068 13.6 0.0 0.2 12.1 0.0 1.9 2 0 0 2 2 2 0 Putative NAD(P)-binding WVELL PF14043.6 AIN98812.1 - 0.034 14.0 0.3 0.071 12.9 0.3 1.5 1 0 0 1 1 1 0 WVELL protein Abhydrolase_2 PF02230.16 AIN98813.1 - 2.6e-39 135.3 0.0 3.2e-39 135.0 0.0 1.1 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Hydrolase_4 PF12146.8 AIN98813.1 - 0.00044 19.6 0.1 0.16 11.2 0.0 2.8 2 1 1 3 3 3 2 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 AIN98813.1 - 0.00055 20.6 0.3 0.00075 20.2 0.3 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family FSH1 PF03959.13 AIN98813.1 - 0.022 14.5 0.0 0.041 13.5 0.0 1.4 1 1 0 1 1 1 0 Serine hydrolase (FSH1) Abhydrolase_1 PF00561.20 AIN98813.1 - 0.049 13.3 0.7 6.6 6.3 0.0 2.7 1 1 0 2 2 2 0 alpha/beta hydrolase fold SPRY PF00622.28 AIN98816.1 - 0.023 14.8 0.0 0.057 13.5 0.0 1.6 1 0 0 1 1 1 0 SPRY domain Cyclin PF08613.11 AIN98817.1 - 1.5e-16 61.2 0.0 2.8e-16 60.3 0.0 1.4 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 AIN98817.1 - 1.7e-07 31.0 0.1 3.2e-07 30.1 0.1 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.11 AIN98818.1 - 1.6e-21 77.3 0.0 4.4e-21 75.9 0.0 1.6 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 AIN98818.1 - 2.1e-07 30.7 0.1 3.4e-07 30.1 0.1 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain ICL PF00463.21 AIN98818.1 - 0.2 10.1 0.0 0.29 9.6 0.0 1.1 1 0 0 1 1 1 0 Isocitrate lyase family PFU PF09070.11 AIN98819.1 - 3.4e-25 88.5 0.3 5.5e-25 87.8 0.3 1.3 1 0 0 1 1 1 1 PFU (PLAA family ubiquitin binding) WD40 PF00400.32 AIN98819.1 - 4.6e-23 81.1 22.9 8.4e-05 23.3 0.0 8.6 8 0 0 8 8 8 5 WD domain, G-beta repeat PUL PF08324.11 AIN98819.1 - 1.6e-07 30.8 1.6 3.1e-07 29.9 1.6 1.4 1 0 0 1 1 1 1 PUL domain AsnC_trans_reg PF01037.21 AIN98819.1 - 0.061 13.3 0.0 2.3 8.3 0.0 3.2 3 0 0 3 3 3 0 Lrp/AsnC ligand binding domain PPTA PF01239.22 AIN98820.1 - 0.0044 16.7 8.6 0.15 11.8 1.9 4.0 3 0 0 3 3 3 2 Protein prenyltransferase alpha subunit repeat DnaJ PF00226.31 AIN98821.1 - 0.14 12.3 0.3 0.25 11.5 0.0 1.6 2 0 0 2 2 2 0 DnaJ domain Pam16 PF03656.13 AIN98821.1 - 0.15 12.1 0.2 0.27 11.2 0.2 1.7 1 1 0 1 1 1 0 Pam16 DUF4574 PF15141.6 AIN98822.1 - 0.0057 16.5 0.6 0.017 15.0 0.6 1.8 1 0 0 1 1 1 1 Ubiquinol-cytochrome-c reductase complex assembly factor 3 UPF0242 PF06785.11 AIN98822.1 - 0.13 12.4 14.8 0.8 9.8 3.1 2.9 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0242) N-terminus ADIP PF11559.8 AIN98822.1 - 2.5 8.2 26.3 0.77 9.8 6.4 3.1 3 0 0 3 3 3 0 Afadin- and alpha -actinin-Binding DUF3138 PF11336.8 AIN98822.1 - 4 5.9 10.9 5.4 5.5 1.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3138) TSC22 PF01166.18 AIN98822.1 - 4.2 7.7 13.5 5.5 7.4 2.1 3.7 2 1 1 3 3 3 0 TSC-22/dip/bun family YabA PF06156.13 AIN98822.1 - 7.7 7.2 15.9 8.1 7.1 0.4 3.7 3 1 1 4 4 4 0 Initiation control protein YabA Ins134_P3_kin PF05770.11 AIN98823.1 - 5.5e-06 26.0 0.0 0.016 14.7 0.0 3.4 3 0 0 3 3 3 3 Inositol 1,3,4-trisphosphate 5/6-kinase ATP-grasp domain LIF_OSM PF01291.17 AIN98825.1 - 0.031 14.4 0.0 0.071 13.2 0.0 1.5 1 0 0 1 1 1 0 LIF / OSM family AMMECR1 PF01871.17 AIN98826.1 - 0.025 14.2 0.1 0.062 12.9 0.1 1.6 1 0 0 1 1 1 0 AMMECR1 Atg14 PF10186.9 AIN98826.1 - 0.49 9.4 33.7 0.044 12.9 21.3 2.6 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 MAD PF05557.13 AIN98826.1 - 1 7.6 37.4 0.22 9.8 21.3 2.1 2 0 0 2 2 2 0 Mitotic checkpoint protein Golgin_A5 PF09787.9 AIN98826.1 - 9.4 5.6 40.9 0.46 9.9 22.9 2.2 2 0 0 2 2 2 0 Golgin subfamily A member 5 PD40 PF07676.12 AIN98827.1 - 0.042 13.8 0.0 0.1 12.6 0.0 1.6 1 0 0 1 1 1 0 WD40-like Beta Propeller Repeat DUF3287 PF11690.8 AIN98827.1 - 0.068 12.9 0.2 0.13 12.0 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3287) AKAP95 PF04988.12 AIN98827.1 - 0.2 11.9 0.3 0.34 11.1 0.3 1.3 1 0 0 1 1 1 0 A-kinase anchoring protein 95 (AKAP95) STOP PF05217.12 AIN98828.1 - 2.8 8.3 14.2 2 8.8 11.5 2.3 2 1 0 2 2 2 0 STOP protein PCIF1_WW PF12237.8 AIN98830.1 - 8.4e-13 48.3 0.0 1.7e-12 47.3 0.0 1.6 1 0 0 1 1 1 1 Phosphorylated CTD interacting factor 1 WW domain PI3_PI4_kinase PF00454.27 AIN98831.1 - 1.7e-42 146.0 0.0 9.2e-28 97.7 0.0 2.3 1 1 1 2 2 2 2 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.20 AIN98831.1 - 3.7e-23 81.9 0.0 8.3e-23 80.7 0.0 1.5 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3K_C2 PF00792.24 AIN98831.1 - 0.00067 19.6 0.0 0.0014 18.5 0.0 1.6 1 0 0 1 1 1 1 Phosphoinositide 3-kinase C2 DUF4135 PF13575.6 AIN98831.1 - 0.021 14.2 0.0 0.034 13.5 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4135) TFCD_C PF12612.8 AIN98832.1 - 1.3e-29 103.4 0.0 6.2e-29 101.2 0.0 2.3 1 0 0 1 1 1 1 Tubulin folding cofactor D C terminal HEAT_2 PF13646.6 AIN98832.1 - 1.1e-10 41.7 14.3 0.0045 17.4 0.1 7.3 6 1 0 6 6 6 3 HEAT repeats Cnd1 PF12717.7 AIN98832.1 - 5.8e-05 23.2 1.3 1.3 9.1 0.0 5.3 6 0 0 6 6 6 1 non-SMC mitotic condensation complex subunit 1 Cnd3 PF12719.7 AIN98832.1 - 0.14 11.3 0.0 8.6 5.5 0.0 3.0 3 0 0 3 3 3 0 Nuclear condensing complex subunits, C-term domain HEAT PF02985.22 AIN98832.1 - 0.48 10.8 47.2 0.49 10.8 0.0 12.0 13 1 1 14 14 14 0 HEAT repeat adh_short_C2 PF13561.6 AIN98833.1 - 3.4e-45 154.4 1.7 4.5e-45 154.0 1.7 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 AIN98833.1 - 3.2e-44 150.7 2.6 4.1e-44 150.4 2.6 1.0 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 AIN98833.1 - 1.3e-09 38.3 3.4 8.3e-09 35.6 3.4 2.0 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 AIN98833.1 - 2.3e-06 27.3 1.0 8.6e-06 25.4 1.0 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 AIN98833.1 - 0.0017 18.2 0.7 0.0022 17.9 0.7 1.3 1 0 0 1 1 1 1 NAD(P)H-binding AlaDh_PNT_C PF01262.21 AIN98833.1 - 0.0025 17.1 0.8 0.0046 16.3 0.8 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Shikimate_DH PF01488.20 AIN98833.1 - 0.0031 17.6 0.5 0.0065 16.5 0.2 1.6 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase Sacchrp_dh_NADP PF03435.18 AIN98833.1 - 0.0063 16.8 1.4 0.01 16.1 1.1 1.6 1 1 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain 3HCDH_N PF02737.18 AIN98833.1 - 0.0077 16.1 0.5 0.014 15.3 0.5 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DAO PF01266.24 AIN98833.1 - 0.015 14.9 0.1 0.021 14.4 0.1 1.3 1 1 0 1 1 1 0 FAD dependent oxidoreductase Polysacc_synt_2 PF02719.15 AIN98833.1 - 0.017 14.2 1.1 0.026 13.7 1.1 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein NAD_binding_8 PF13450.6 AIN98833.1 - 0.037 14.2 0.1 0.095 13.0 0.1 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain ApbA PF02558.16 AIN98833.1 - 0.045 13.4 0.1 0.08 12.6 0.1 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA FAD_binding_3 PF01494.19 AIN98833.1 - 0.048 12.9 0.1 0.077 12.2 0.1 1.3 1 0 0 1 1 1 0 FAD binding domain TrkA_N PF02254.18 AIN98833.1 - 0.053 13.8 1.5 0.069 13.4 0.3 1.7 2 0 0 2 2 2 0 TrkA-N domain Glyco_transf_4 PF13439.6 AIN98833.1 - 0.1 12.6 0.0 2.2 8.2 0.0 2.2 2 0 0 2 2 2 0 Glycosyltransferase Family 4 GDP_Man_Dehyd PF16363.5 AIN98833.1 - 0.13 11.6 0.0 0.47 9.8 0.0 1.7 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase DFP PF04127.15 AIN98833.1 - 0.52 10.1 4.7 0.3 10.9 0.8 2.0 1 1 0 2 2 2 0 DNA / pantothenate metabolism flavoprotein BolA PF01722.18 AIN98834.1 - 1.1e-14 54.4 0.0 1.4e-14 54.1 0.0 1.2 1 0 0 1 1 1 1 BolA-like protein Ribosomal_L26 PF16906.5 AIN98835.1 - 1.8e-37 127.7 1.3 2.3e-37 127.3 1.3 1.1 1 0 0 1 1 1 1 Ribosomal proteins L26 eukaryotic, L24P archaeal KOW PF00467.29 AIN98835.1 - 4e-06 26.6 0.5 1e-05 25.3 0.5 1.8 1 1 0 1 1 1 1 KOW motif Transketolase_N PF00456.21 AIN98836.1 - 1.1e-138 461.8 0.1 1.5e-138 461.3 0.1 1.2 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.24 AIN98836.1 - 6.5e-45 153.0 0.0 1.3e-44 152.0 0.0 1.4 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 AIN98836.1 - 1.1e-08 35.0 0.0 2.4e-08 33.9 0.0 1.6 1 0 0 1 1 1 1 Transketolase, C-terminal domain DXP_synthase_N PF13292.6 AIN98836.1 - 0.0001 21.6 0.0 0.00033 20.0 0.0 1.7 1 1 1 2 2 2 1 1-deoxy-D-xylulose-5-phosphate synthase TPP_enzyme_C PF02775.21 AIN98836.1 - 0.00016 21.5 0.2 0.00078 19.3 0.1 2.2 1 1 1 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Terpene_synth PF01397.21 AIN98836.1 - 0.0033 17.1 0.0 0.0078 15.9 0.0 1.5 1 0 0 1 1 1 1 Terpene synthase, N-terminal domain E1_dh PF00676.20 AIN98836.1 - 0.087 11.8 0.0 0.23 10.4 0.0 1.5 1 1 0 1 1 1 0 Dehydrogenase E1 component Ribosomal_S8e PF01201.22 AIN98837.1 - 1.2e-46 158.3 2.4 1.4e-46 158.1 2.4 1.1 1 0 0 1 1 1 1 Ribosomal protein S8e Kelch_3 PF13415.6 AIN98838.1 - 3.5e-39 132.4 6.6 2.3e-09 37.3 0.0 7.3 7 1 0 7 7 7 6 Galactose oxidase, central domain Kelch_1 PF01344.25 AIN98838.1 - 1.5e-36 123.7 20.7 3.7e-08 32.8 0.0 6.4 6 0 0 6 6 6 6 Kelch motif Kelch_4 PF13418.6 AIN98838.1 - 6.3e-34 115.7 18.8 2e-06 27.7 0.1 6.9 5 1 1 6 6 6 6 Galactose oxidase, central domain Kelch_5 PF13854.6 AIN98838.1 - 2.3e-31 107.3 15.6 1.9e-07 30.9 0.5 6.3 6 0 0 6 6 6 6 Kelch motif Kelch_6 PF13964.6 AIN98838.1 - 1.6e-29 101.1 10.2 2.4e-07 30.8 0.0 6.5 5 1 1 6 6 6 5 Kelch motif Kelch_2 PF07646.15 AIN98838.1 - 1.3e-26 91.5 15.3 1.8e-06 27.7 0.4 6.4 6 1 0 6 6 6 6 Kelch motif HMG_CoA_synt_N PF01154.17 AIN98840.1 - 1.8e-11 44.3 0.1 3.1e-11 43.4 0.1 1.4 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal HMG_CoA_synt_C PF08540.10 AIN98840.1 - 1.2e-06 28.4 0.1 9.2e-05 22.2 0.0 2.6 2 1 0 2 2 2 1 Hydroxymethylglutaryl-coenzyme A synthase C terminal ACP_syn_III PF08545.10 AIN98840.1 - 0.028 14.3 0.9 0.05 13.5 0.2 1.8 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III UQ_con PF00179.26 AIN98842.1 - 1.5e-44 151.1 0.2 1.6e-44 150.9 0.2 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UEV PF05743.13 AIN98842.1 - 0.00087 19.1 0.3 0.0015 18.4 0.3 1.4 1 1 0 1 1 1 1 UEV domain RWD PF05773.22 AIN98842.1 - 0.0009 19.5 0.2 0.0012 19.1 0.2 1.4 1 1 0 1 1 1 1 RWD domain Prok-E2_B PF14461.6 AIN98842.1 - 0.0094 15.7 0.0 0.012 15.4 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B UQ_con PF00179.26 AIN98843.1 - 4.6e-07 29.6 0.0 9.2e-07 28.6 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 AIN98843.1 - 0.13 12.5 0.0 0.21 11.9 0.0 1.4 1 0 0 1 1 1 0 RWD domain HK_sensor PF16750.5 AIN98844.1 - 0.086 13.1 0.2 0.11 12.7 0.2 1.3 1 0 0 1 1 1 0 Sensor domain of 2-component histidine kinase Nbs1_C PF08599.10 AIN98844.1 - 0.12 12.5 0.2 0.67 10.1 0.1 2.2 2 1 1 3 3 3 0 DNA damage repair protein Nbs1 GDPD PF03009.17 AIN98845.1 - 2.9e-21 76.4 0.0 3.9e-21 75.9 0.0 1.1 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family Utp8 PF10395.9 AIN98845.1 - 0.12 10.9 0.0 0.15 10.6 0.0 1.0 1 0 0 1 1 1 0 Utp8 family Vps54_N PF10475.9 AIN98846.1 - 3.3e-13 49.6 5.6 5.5e-13 48.9 4.9 1.7 1 1 0 1 1 1 1 Vacuolar-sorting protein 54, of GARP complex DUF2451 PF10474.9 AIN98846.1 - 2.5e-12 47.1 2.6 1.5e-11 44.5 0.3 2.8 3 0 0 3 3 3 1 Protein of unknown function C-terminus (DUF2451) Sec8_exocyst PF04048.14 AIN98846.1 - 0.00069 19.5 0.5 0.0016 18.4 0.5 1.5 1 0 0 1 1 1 1 Sec8 exocyst complex component specific domain Vps51 PF08700.11 AIN98846.1 - 0.12 12.5 0.1 0.33 11.1 0.1 1.7 1 0 0 1 1 1 0 Vps51/Vps67 FlxA PF14282.6 AIN98847.1 - 0.0079 16.2 4.6 0.0079 16.2 4.6 14.4 6 3 11 18 18 18 2 FlxA-like protein DUF3800 PF12686.7 AIN98847.1 - 0.14 12.7 0.2 69 4.1 0.7 5.0 2 2 0 2 2 2 0 Protein of unknown function (DUF3800) NRN1 PF15056.6 AIN98847.1 - 0.65 10.1 19.0 0.41 10.8 0.4 5.7 5 0 0 5 5 5 0 Neuritin protein family GGDEF_2 PF17853.1 AIN98848.1 - 0.11 12.7 1.1 0.27 11.5 0.1 2.1 2 1 0 2 2 2 0 GGDEF-like domain DUF2140 PF09911.9 AIN98848.1 - 0.17 11.5 0.2 0.3 10.6 0.0 1.5 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2140) PPR_3 PF13812.6 AIN98849.1 - 7.1e-12 45.2 0.0 1.6e-05 24.9 0.0 2.8 2 1 0 3 3 3 2 Pentatricopeptide repeat domain PPR_2 PF13041.6 AIN98849.1 - 4.3e-06 26.8 0.0 0.0057 16.8 0.0 2.8 2 1 1 3 3 3 2 PPR repeat family PPR_long PF17177.4 AIN98849.1 - 3.2e-05 23.4 0.0 0.17 11.2 0.1 2.2 1 1 1 2 2 2 2 Pentacotripeptide-repeat region of PRORP PPR PF01535.20 AIN98849.1 - 0.019 15.2 0.0 9 6.8 0.0 3.2 3 0 0 3 3 3 0 PPR repeat Ribosomal_L11_N PF03946.14 AIN98850.1 - 1e-16 60.5 0.5 1.8e-16 59.7 0.5 1.5 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.19 AIN98850.1 - 1.7e-13 50.8 0.8 1.7e-13 50.8 0.8 1.7 2 0 0 2 2 2 1 Ribosomal protein L11, RNA binding domain DUF3792 PF12670.7 AIN98852.1 - 0.16 12.2 6.2 0.35 11.0 5.9 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF3792) Cob_adeno_trans PF01923.18 AIN98853.1 - 1.1e-51 175.2 0.3 1.7e-51 174.6 0.3 1.3 1 0 0 1 1 1 1 Cobalamin adenosyltransferase DUF5522 PF17653.1 AIN98853.1 - 3.7e-20 71.6 2.6 3.7e-20 71.6 2.6 1.9 2 0 0 2 2 2 1 Family of unknown function (DUF5522) FA_desaturase PF00487.24 AIN98854.1 - 5.1e-18 65.8 20.5 5.1e-18 65.8 20.5 1.4 1 1 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.28 AIN98854.1 - 1.2e-08 35.0 0.1 1e-06 28.8 0.1 3.2 3 0 0 3 3 3 1 Cytochrome b5-like Heme/Steroid binding domain DUF2269 PF10027.9 AIN98854.1 - 0.037 14.1 1.1 0.08 13.0 1.1 1.5 1 0 0 1 1 1 0 Predicted integral membrane protein (DUF2269) TssN PF17555.2 AIN98854.1 - 0.095 12.1 0.1 0.095 12.1 0.1 2.2 2 0 0 2 2 2 0 Type VI secretion system, TssN CAF1 PF04857.20 AIN98854.1 - 0.12 11.5 0.0 0.13 11.4 0.0 1.1 1 0 0 1 1 1 0 CAF1 family ribonuclease WD40 PF00400.32 AIN98855.1 - 1e-52 174.9 32.9 4.3e-08 33.7 0.1 8.9 8 1 0 8 8 8 8 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 AIN98855.1 - 1.1e-19 70.5 6.4 0.003 17.8 0.0 6.4 2 2 4 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain NLE PF08154.12 AIN98855.1 - 4.3e-12 46.4 0.0 7.5e-12 45.6 0.0 1.4 1 0 0 1 1 1 1 NLE (NUC135) domain Ge1_WD40 PF16529.5 AIN98855.1 - 2.3e-08 33.4 0.6 0.037 13.0 0.0 4.3 3 2 1 4 4 4 3 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 AIN98855.1 - 1.6e-06 27.7 0.0 0.33 10.3 0.0 3.3 2 1 1 3 3 3 3 WD40-like domain eIF2A PF08662.11 AIN98855.1 - 2.3e-06 27.6 0.1 0.078 12.8 0.0 2.6 2 0 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A PD40 PF07676.12 AIN98855.1 - 3.6e-05 23.6 1.9 8.4 6.5 0.0 4.9 5 0 0 5 5 5 3 WD40-like Beta Propeller Repeat Nbas_N PF15492.6 AIN98855.1 - 0.00033 20.1 0.2 0.21 10.9 0.0 3.6 2 2 1 3 3 3 1 Neuroblastoma-amplified sequence, N terminal EBP PF05241.12 AIN98855.1 - 0.12 11.9 0.6 0.22 11.0 0.2 1.6 1 1 0 1 1 1 0 Emopamil binding protein DHHC PF01529.20 AIN98856.1 - 1.3e-13 51.2 10.6 1.3e-13 51.2 10.6 3.4 2 2 0 2 2 2 1 DHHC palmitoyltransferase zf-LITAF-like PF10601.9 AIN98856.1 - 0.041 14.1 1.0 0.041 14.1 1.0 3.2 3 1 1 4 4 4 0 LITAF-like zinc ribbon domain DUF35_N PF12172.8 AIN98856.1 - 0.12 12.3 3.4 0.32 10.9 0.7 2.5 2 0 0 2 2 2 0 Rubredoxin-like zinc ribbon domain (DUF35_N) DEAD_2 PF06733.15 AIN98857.1 - 6.6e-40 136.6 0.0 7.1e-39 133.2 0.0 2.3 2 0 0 2 2 2 1 DEAD_2 Helicase_C_2 PF13307.6 AIN98857.1 - 6.7e-39 133.8 0.0 1.5e-38 132.7 0.0 1.6 1 0 0 1 1 1 1 Helicase C-terminal domain HBB PF06777.11 AIN98857.1 - 6.1e-34 117.4 0.8 1.5e-28 99.8 0.3 2.6 2 0 0 2 2 2 2 Helical and beta-bridge domain DEAD PF00270.29 AIN98857.1 - 0.00012 21.9 0.4 0.01 15.6 0.0 2.5 2 0 0 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.15 AIN98857.1 - 0.00019 21.5 0.1 0.0027 17.7 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Glyco_transf_21 PF13506.6 AIN98857.1 - 0.013 15.0 0.4 0.1 12.0 0.0 2.7 3 0 0 3 3 3 0 Glycosyl transferase family 21 Flavi_DEAD PF07652.14 AIN98857.1 - 0.015 15.3 0.8 0.73 9.8 0.1 2.6 2 0 0 2 2 2 0 Flavivirus DEAD domain AAA_19 PF13245.6 AIN98857.1 - 0.033 14.5 0.1 0.13 12.6 0.1 1.9 1 1 0 1 1 1 0 AAA domain AAA_22 PF13401.6 AIN98857.1 - 0.064 13.5 0.9 0.55 10.5 0.0 2.8 3 0 0 3 3 3 0 AAA domain CorC_HlyC PF03471.17 AIN98857.1 - 0.11 12.5 0.0 0.39 10.7 0.0 1.9 2 0 0 2 2 2 0 Transporter associated domain SAPIS-gp6 PF16722.5 AIN98857.1 - 0.16 12.4 0.9 0.33 11.4 0.9 1.5 1 0 0 1 1 1 0 Pathogenicity island protein gp6 in Staphylococcus Cullin PF00888.22 AIN98858.1 - 9.4e-79 265.6 0.0 1.2e-78 265.3 0.0 1.1 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 AIN98858.1 - 1.9e-22 79.1 0.6 5.5e-22 77.6 0.6 1.9 1 0 0 1 1 1 1 Cullin protein neddylation domain DUF682 PF05081.12 AIN98860.1 - 0.07 12.9 1.0 0.1 12.3 0.8 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF682) DUF1319 PF07028.11 AIN98860.1 - 0.16 12.2 5.9 1.3 9.3 3.2 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1319) Baculo_PEP_C PF04513.12 AIN98860.1 - 0.16 12.0 2.7 0.21 11.6 0.2 2.0 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Exonuc_VII_L PF02601.15 AIN98860.1 - 1.4 8.4 7.1 1.6 8.2 7.1 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit Enkurin PF13864.6 AIN98860.1 - 1.7 9.1 10.5 12 6.4 10.5 2.2 1 1 0 1 1 1 0 Calmodulin-binding ABC_tran_CTD PF16326.5 AIN98860.1 - 2 8.7 15.8 0.31 11.3 0.8 3.8 2 1 2 4 4 4 0 ABC transporter C-terminal domain DUF1664 PF07889.12 AIN98860.1 - 3.9 7.5 6.9 2 8.5 1.1 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Pkinase PF00069.25 AIN98861.1 - 5.3e-62 209.6 0.0 6.2e-62 209.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 AIN98861.1 - 9.5e-41 139.8 0.0 1.2e-40 139.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase FTA2 PF13095.6 AIN98861.1 - 5.2e-05 23.0 0.1 0.009 15.7 0.0 2.2 1 1 1 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 Kinase-like PF14531.6 AIN98861.1 - 0.00043 19.7 0.0 0.0011 18.4 0.0 1.5 1 1 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 AIN98861.1 - 0.0014 17.5 0.0 0.0022 16.9 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase SpoU_methylase PF00588.19 AIN98863.1 - 4.2e-16 59.4 0.1 1.8e-09 37.9 0.0 2.4 2 0 0 2 2 2 2 SpoU rRNA Methylase family DUF2442 PF10387.9 AIN98863.1 - 0.017 15.4 0.2 0.087 13.1 0.0 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2442) Glycos_transf_2 PF00535.26 AIN98867.1 - 2.8e-09 37.0 0.0 5.4e-09 36.1 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 2 FR47 PF08445.10 AIN98868.1 - 4.6e-07 29.7 0.0 6.6e-07 29.2 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.7 AIN98868.1 - 5.1e-06 26.4 0.1 7e-06 26.0 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 AIN98868.1 - 1.6e-05 25.1 0.0 2.1e-05 24.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family DUF2431 PF10354.9 AIN98869.1 - 9.9e-24 84.5 0.0 2.6e-23 83.1 0.0 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF2431) zf-C2H2 PF00096.26 AIN98869.1 - 2.1e-05 24.7 9.2 0.073 13.6 0.5 4.0 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.8 AIN98869.1 - 2.2e-05 24.6 0.9 0.0015 18.8 0.1 3.2 3 0 0 3 3 3 1 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.6 AIN98869.1 - 6.1e-05 23.5 7.8 4.1 8.5 0.2 4.2 3 0 0 3 3 3 3 C2H2-type zinc finger zf-met PF12874.7 AIN98869.1 - 0.0023 18.3 0.1 0.0023 18.3 0.1 2.8 2 1 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 AIN98869.1 - 0.063 13.3 0.0 0.063 13.3 0.0 3.0 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2_2 PF12756.7 AIN98869.1 - 1.2 9.6 3.5 1.8 8.9 0.3 2.4 2 1 0 2 2 2 0 C2H2 type zinc-finger (2 copies) YabA PF06156.13 AIN98870.1 - 0.01 16.5 0.3 0.01 16.5 0.3 3.7 3 1 0 4 4 4 0 Initiation control protein YabA TSC22 PF01166.18 AIN98870.1 - 0.044 14.1 4.8 0.22 11.8 1.8 3.1 1 1 1 2 2 2 0 TSC-22/dip/bun family DUF4874 PF16173.5 AIN98870.1 - 0.089 12.5 0.0 0.19 11.4 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4874) CEP44 PF15007.6 AIN98871.1 - 0.00045 20.4 0.0 0.00057 20.0 0.0 1.1 1 0 0 1 1 1 1 Centrosomal spindle body, CEP44 Got1 PF04178.12 AIN98872.1 - 1.8e-26 92.8 17.2 2.3e-26 92.4 17.2 1.2 1 0 0 1 1 1 1 Got1/Sft2-like family AzlD PF05437.12 AIN98872.1 - 0.21 11.8 9.9 2.4 8.4 10.7 2.0 1 1 1 2 2 2 0 Branched-chain amino acid transport protein (AzlD) DUF3270 PF11674.8 AIN98872.1 - 0.74 10.0 4.2 0.85 9.8 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3270) RRM_1 PF00076.22 AIN98874.1 - 3.9e-63 209.2 0.7 5.2e-20 71.0 0.0 4.4 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP PF00658.18 AIN98874.1 - 2.3e-18 66.1 0.1 5.1e-18 65.0 0.1 1.6 1 0 0 1 1 1 1 Poly-adenylate binding protein, unique domain RRM_occluded PF16842.5 AIN98874.1 - 6.2e-07 29.2 0.0 0.00055 19.7 0.0 3.8 4 0 0 4 4 4 1 Occluded RNA-recognition motif RRM_7 PF16367.5 AIN98874.1 - 6.4e-06 26.2 0.1 0.12 12.5 0.0 4.5 4 2 0 4 4 4 2 RNA recognition motif PHM7_cyt PF14703.6 AIN98874.1 - 0.00028 21.2 0.2 7.8 6.7 0.0 4.5 3 2 2 5 5 5 2 Cytosolic domain of 10TM putative phosphate transporter Mlh1_C PF16413.5 AIN98874.1 - 0.041 13.3 0.0 0.068 12.5 0.0 1.3 1 0 0 1 1 1 0 DNA mismatch repair protein Mlh1 C-terminus OB_RNB PF08206.11 AIN98874.1 - 0.045 13.4 0.5 0.87 9.3 0.1 2.5 2 0 0 2 2 2 0 Ribonuclease B OB domain RPAP1_N PF08621.10 AIN98875.1 - 0.0011 18.7 4.6 0.12 12.1 0.7 2.2 2 0 0 2 2 2 2 RPAP1-like, N-terminal Laminin_II PF06009.12 AIN98875.1 - 0.0026 17.8 0.8 0.0034 17.4 0.8 1.3 1 0 0 1 1 1 1 Laminin Domain II APG17 PF04108.12 AIN98875.1 - 0.0087 15.2 1.2 0.01 15.0 1.2 1.0 1 0 0 1 1 1 1 Autophagy protein Apg17 DUF745 PF05335.13 AIN98875.1 - 0.011 15.5 2.3 0.014 15.2 2.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF745) Mitofilin PF09731.9 AIN98875.1 - 0.029 13.2 1.9 0.034 13.0 1.9 1.0 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Sec20 PF03908.13 AIN98875.1 - 0.04 13.8 1.4 0.4 10.6 0.7 2.0 1 1 1 2 2 2 0 Sec20 DUF2207 PF09972.9 AIN98875.1 - 0.044 12.6 0.1 0.051 12.4 0.1 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Spidroin_N PF16763.5 AIN98875.1 - 0.067 13.2 1.2 0.086 12.9 1.2 1.1 1 0 0 1 1 1 0 Major ampullate spidroin 1, spider silk protein 1, N-term DUF364 PF04016.12 AIN98876.1 - 0.032 13.8 0.0 0.037 13.6 0.0 1.0 1 0 0 1 1 1 0 Putative heavy-metal chelation CrgA PF06781.12 AIN98876.1 - 0.042 13.9 0.3 0.047 13.8 0.3 1.1 1 0 0 1 1 1 0 Cell division protein CrgA DUF4044 PF13253.6 AIN98876.1 - 0.23 11.0 2.7 0.41 10.2 2.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4044) ETF PF01012.21 AIN98878.1 - 5.8e-43 146.9 3.1 7.1e-43 146.6 3.1 1.1 1 0 0 1 1 1 1 Electron transfer flavoprotein domain PIG-L PF02585.17 AIN98878.1 - 0.0055 17.3 0.0 0.009 16.6 0.0 1.4 1 0 0 1 1 1 1 GlcNAc-PI de-N-acetylase GTP_EFTU PF00009.27 AIN98879.1 - 3.7e-50 170.2 0.1 5.6e-50 169.6 0.1 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.24 AIN98879.1 - 1.5e-13 50.6 0.0 3.6e-13 49.3 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus Septin PF00735.18 AIN98879.1 - 1.4e-05 24.5 0.1 2.4e-05 23.8 0.1 1.3 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.23 AIN98879.1 - 1.8e-05 24.8 0.1 3.8e-05 23.7 0.1 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase EFG_II PF14492.6 AIN98879.1 - 0.0045 17.1 0.0 0.016 15.3 0.0 2.0 1 0 0 1 1 1 1 Elongation Factor G, domain II RnfC_N PF13375.6 AIN98879.1 - 0.12 12.3 0.1 0.78 9.7 0.0 2.3 2 0 0 2 2 2 0 RnfC Barrel sandwich hybrid domain RNA_pol_Rpb6 PF01192.22 AIN98880.1 - 5.2e-09 35.9 0.0 1e-08 35.0 0.0 1.5 1 1 0 1 1 1 1 RNA polymerase Rpb6 DivIC PF04977.15 AIN98882.1 - 0.13 12.1 8.2 0.16 11.7 0.3 3.1 2 1 1 3 3 3 0 Septum formation initiator Lactamase_B_6 PF16661.5 AIN98883.1 - 1.5e-19 70.2 0.0 2.5e-19 69.5 0.0 1.3 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily domain CPSF100_C PF13299.6 AIN98883.1 - 1.5e-13 51.3 0.3 1.5e-13 51.3 0.3 2.7 2 1 0 2 2 2 1 Cleavage and polyadenylation factor 2 C-terminal Lactamase_B PF00753.27 AIN98883.1 - 0.00042 20.4 0.2 0.001 19.1 0.2 1.7 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Beta-Casp PF10996.8 AIN98883.1 - 0.062 13.6 0.0 0.22 11.9 0.0 1.9 2 0 0 2 2 2 0 Beta-Casp domain Peptidase_C12 PF01088.21 AIN98885.1 - 1.6e-53 181.6 0.0 1.8e-53 181.4 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 WD40_3 PF15911.5 AIN98886.1 - 1.6e-14 53.6 0.0 5.3e-13 48.8 0.0 2.9 2 0 0 2 2 2 1 WD domain, G-beta repeat Clathrin PF00637.20 AIN98886.1 - 2.8e-07 30.5 2.2 0.00059 19.7 0.2 3.9 4 0 0 4 4 4 2 Region in Clathrin and VPS ANAPC4_WD40 PF12894.7 AIN98886.1 - 5.7e-07 29.7 0.0 0.16 12.3 0.0 3.7 3 0 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain TPR_14 PF13428.6 AIN98886.1 - 0.0053 17.5 8.3 33 5.6 0.0 6.0 6 1 2 8 8 5 0 Tetratricopeptide repeat ANAPC3 PF12895.7 AIN98886.1 - 0.014 15.7 5.5 0.047 13.9 0.8 4.2 3 2 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.6 AIN98886.1 - 0.016 15.2 6.6 7.2 6.9 0.1 6.0 7 0 0 7 7 7 0 Tetratricopeptide repeat KNOX2 PF03791.13 AIN98886.1 - 0.028 13.9 0.0 0.075 12.6 0.0 1.7 1 0 0 1 1 1 0 KNOX2 domain TPR_19 PF14559.6 AIN98886.1 - 0.029 14.9 8.8 0.12 12.9 0.0 5.1 4 2 2 6 6 6 0 Tetratricopeptide repeat WD40 PF00400.32 AIN98886.1 - 0.063 14.2 4.9 7.2 7.7 0.2 4.9 4 0 0 4 4 4 0 WD domain, G-beta repeat Coatomer_WDAD PF04053.14 AIN98886.1 - 0.077 12.0 1.9 2.3 7.2 0.3 3.7 3 1 1 4 4 4 0 Coatomer WD associated region Mad3_BUB1_I PF08311.12 AIN98886.1 - 0.39 10.7 2.3 8.9 6.3 0.1 3.3 3 0 0 3 3 3 0 Mad3/BUB1 homology region 1 TPR_12 PF13424.6 AIN98886.1 - 0.63 10.4 13.2 46 4.4 0.2 6.3 6 0 0 6 6 6 0 Tetratricopeptide repeat zf-ribbon_3 PF13248.6 AIN98886.1 - 0.88 9.1 5.6 3.6 7.1 2.6 2.7 2 0 0 2 2 2 0 zinc-ribbon domain Mito_carr PF00153.27 AIN98887.1 - 1.5e-59 197.9 0.5 2.8e-20 72.0 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein SyrA PF11089.8 AIN98888.1 - 0.035 14.2 1.9 0.067 13.3 1.9 1.4 1 0 0 1 1 1 0 Exopolysaccharide production repressor GRP PF07172.11 AIN98888.1 - 0.39 11.4 18.8 0.52 11.0 15.2 2.4 2 0 0 2 2 2 0 Glycine rich protein family Spt5_N PF11942.8 AIN98888.1 - 2.9 8.9 8.1 2.1 9.4 0.3 2.5 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal DSPc PF00782.20 AIN98889.1 - 2.1e-15 56.7 0.1 3.4e-15 56.0 0.1 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.6 AIN98889.1 - 2.7e-05 24.3 0.1 6.2e-05 23.2 0.1 1.6 1 0 0 1 1 1 1 Inositol hexakisphosphate Y_phosphatase PF00102.27 AIN98889.1 - 0.0054 16.3 0.2 0.0077 15.8 0.2 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase CDKN3 PF05706.12 AIN98889.1 - 0.014 15.1 0.1 0.025 14.3 0.1 1.3 1 0 0 1 1 1 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) Y_phosphatase3 PF13350.6 AIN98889.1 - 0.032 14.2 0.0 0.049 13.6 0.0 1.3 1 0 0 1 1 1 0 Tyrosine phosphatase family Bud13 PF09736.9 AIN98890.1 - 1.6e-06 28.6 0.1 2.4e-06 28.0 0.1 1.3 1 0 0 1 1 1 1 Pre-mRNA-splicing factor of RES complex DUF3135 PF11333.8 AIN98891.1 - 0.0038 17.4 5.5 0.35 11.2 1.3 3.1 2 0 0 2 2 2 2 Protein of unknown function (DUF3135) FH2 PF02181.23 AIN98891.1 - 3.6 6.6 11.4 3.3 6.7 3.4 2.3 2 0 0 2 2 2 0 Formin Homology 2 Domain Dynein_light PF01221.18 AIN98892.1 - 7.6e-33 112.7 0.3 8.4e-33 112.6 0.3 1.0 1 0 0 1 1 1 1 Dynein light chain type 1 N_NLPC_P60 PF12912.7 AIN98892.1 - 0.13 12.6 0.0 0.15 12.5 0.0 1.2 1 0 0 1 1 1 0 NLPC_P60 stabilising domain, N term MutS_III PF05192.18 AIN98894.1 - 0.0077 16.5 0.8 3.7 7.7 4.9 2.3 2 1 0 2 2 2 1 MutS domain III DUF3450 PF11932.8 AIN98894.1 - 0.011 15.1 0.1 0.011 15.1 0.1 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3450) zf-C4H2 PF10146.9 AIN98894.1 - 0.043 14.1 0.7 0.67 10.2 0.1 2.6 2 0 0 2 2 2 0 Zinc finger-containing protein SAS4 PF15460.6 AIN98894.1 - 0.53 10.4 4.4 0.42 10.7 0.8 2.4 2 0 0 2 2 2 0 Something about silencing, SAS, complex subunit 4 TMPIT PF07851.13 AIN98894.1 - 2.2 7.4 6.1 7.5 5.7 3.8 2.2 2 0 0 2 2 2 0 TMPIT-like protein RRM_1 PF00076.22 AIN98895.1 - 3.5e-05 23.5 0.1 0.002 17.9 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Diphthami_syn_2 PF01902.17 AIN98896.1 - 2.1e-32 112.4 0.1 3.3e-30 105.3 0.1 2.9 1 1 0 1 1 1 1 Diphthamide synthase BRCT_2 PF16589.5 AIN98898.1 - 5.8e-08 33.0 0.0 0.00024 21.5 0.0 2.5 2 0 0 2 2 2 2 BRCT domain, a BRCA1 C-terminus domain B9-C2 PF07162.11 AIN98899.1 - 2e-11 44.4 0.1 2.8e-11 43.9 0.1 1.3 1 0 0 1 1 1 1 Ciliary basal body-associated, B9 protein SPRY PF00622.28 AIN98900.1 - 3.9e-06 27.0 0.0 7.1e-06 26.1 0.0 1.3 1 0 0 1 1 1 1 SPRY domain DUF1308 PF07000.11 AIN98901.1 - 1.7e-20 73.6 0.0 1e-19 71.0 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF1308) DUF89 PF01937.19 AIN98901.1 - 0.14 11.1 0.0 0.24 10.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function DUF89 Fcf2 PF08698.11 AIN98903.1 - 1.3e-07 31.9 6.2 9.3e-07 29.2 6.2 2.3 1 1 0 1 1 1 1 Fcf2 pre-rRNA processing SUI1 PF01253.22 AIN98907.1 - 1e-18 67.6 0.0 2.4e-18 66.4 0.0 1.6 1 0 0 1 1 1 1 Translation initiation factor SUI1 TMCO5 PF14992.6 AIN98908.1 - 0.023 14.3 0.1 0.023 14.3 0.1 2.7 1 1 0 2 2 2 0 TMCO5 family CLZ PF16526.5 AIN98908.1 - 0.025 14.9 0.2 0.025 14.9 0.2 6.1 6 1 1 7 7 7 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels FtsX_ECD PF18075.1 AIN98908.1 - 0.095 13.3 3.5 8.7 7.1 0.4 3.3 2 0 0 2 2 2 0 FtsX extracellular domain Noelin-1 PF12308.8 AIN98908.1 - 4.7 7.2 22.7 0.075 13.0 1.3 5.6 4 1 1 5 5 5 0 Neurogenesis glycoprotein Baculo_PEP_C PF04513.12 AIN98908.1 - 8.4 6.4 43.3 0.17 11.9 0.4 7.4 4 1 3 8 8 8 0 Baculovirus polyhedron envelope protein, PEP, C terminus WD40 PF00400.32 AIN98909.1 - 4.2e-37 125.5 16.9 3.1e-08 34.1 0.8 8.3 7 0 0 7 7 7 7 WD domain, G-beta repeat Utp13 PF08625.11 AIN98909.1 - 2.6e-32 111.7 1.6 4.7e-32 110.8 1.6 1.4 1 0 0 1 1 1 1 Utp13 specific WD40 associated domain ANAPC4_WD40 PF12894.7 AIN98909.1 - 2.8e-14 53.2 6.9 5.8e-06 26.5 0.0 6.3 4 2 2 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 AIN98909.1 - 1.7e-05 24.0 1.8 1.4 7.8 0.2 4.6 3 2 1 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 AIN98909.1 - 0.0028 17.1 0.1 1.2 8.4 0.0 3.7 4 2 1 5 5 5 1 WD40-like domain UTP15_C PF09384.10 AIN98909.1 - 0.003 17.3 1.7 0.0067 16.1 1.7 1.5 1 0 0 1 1 1 1 UTP15 C terminal Nup160 PF11715.8 AIN98909.1 - 0.0065 15.2 5.9 2.5 6.6 0.2 4.0 2 1 1 4 4 4 2 Nucleoporin Nup120/160 Utp12 PF04003.12 AIN98909.1 - 0.008 16.5 1.0 0.018 15.3 1.0 1.6 1 0 0 1 1 1 1 Dip2/Utp12 Family HCV_NS5a_1b PF08301.13 AIN98909.1 - 0.0097 16.5 0.1 0.037 14.6 0.1 2.0 1 0 0 1 1 1 1 Hepatitis C virus non-structural 5a domain 1b PHTB1_N PF14727.6 AIN98909.1 - 0.027 13.8 0.7 0.4 10.0 0.1 2.4 2 0 0 2 2 2 0 PTHB1 N-terminus MMS1_N PF10433.9 AIN98909.1 - 0.032 12.9 0.1 0.27 9.8 0.0 2.5 3 0 0 3 3 3 0 Mono-functional DNA-alkylating methyl methanesulfonate N-term TFIIB PF00382.19 AIN98910.1 - 1.1e-23 83.0 0.1 1.2e-11 44.5 0.0 2.5 2 0 0 2 2 2 2 Transcription factor TFIIB repeat TF_Zn_Ribbon PF08271.12 AIN98910.1 - 0.14 11.7 0.1 0.32 10.5 0.1 1.6 1 0 0 1 1 1 0 TFIIB zinc-binding MMR_HSR1 PF01926.23 AIN98911.1 - 1.7e-13 50.7 0.0 2.8e-13 50.0 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 AIN98911.1 - 1.5e-07 31.1 0.0 8.4e-06 25.4 0.0 2.2 2 0 0 2 2 2 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 AIN98911.1 - 4.4e-06 26.7 0.0 5.2e-05 23.2 0.0 2.2 2 0 0 2 2 2 1 RsgA GTPase Dynamin_N PF00350.23 AIN98911.1 - 0.00039 20.5 0.5 0.17 11.9 0.2 2.4 1 1 1 2 2 2 2 Dynamin family AIG1 PF04548.16 AIN98911.1 - 0.00053 19.4 0.0 0.00091 18.6 0.0 1.4 1 0 0 1 1 1 1 AIG1 family GTP_EFTU PF00009.27 AIN98911.1 - 0.00068 19.2 0.0 0.11 12.1 0.1 2.6 1 1 1 2 2 2 2 Elongation factor Tu GTP binding domain SRPRB PF09439.10 AIN98911.1 - 0.01 15.3 0.0 0.016 14.6 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit ATP-synt_F6 PF05511.11 AIN98912.1 - 0.15 12.4 0.0 0.43 11.0 0.0 1.6 2 0 0 2 2 2 0 Mitochondrial ATP synthase coupling factor 6 Kringle PF00051.18 AIN98913.1 - 3.9e-15 55.9 0.4 7.7e-15 55.0 0.4 1.5 1 0 0 1 1 1 1 Kringle domain CHB_HEX_C_1 PF13290.6 AIN98913.1 - 1.9e-05 24.6 1.1 0.00021 21.2 0.1 2.9 2 0 0 2 2 2 1 Chitobiase/beta-hexosaminidase C-terminal domain Fn3_assoc PF13287.6 AIN98913.1 - 0.0059 16.7 0.0 0.024 14.8 0.0 2.1 1 0 0 1 1 1 1 Fn3 associated RRM_1 PF00076.22 AIN98915.1 - 2.6e-21 75.2 0.0 3.4e-21 74.8 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 AIN98915.1 - 2.8e-06 26.9 0.0 4.9e-06 26.1 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 AIN98915.1 - 0.0025 17.6 0.0 0.0049 16.7 0.0 1.5 1 1 0 1 1 1 1 Occluded RNA-recognition motif Nrf1_DNA-bind PF10491.9 AIN98915.1 - 0.11 12.2 0.3 0.19 11.4 0.1 1.5 2 0 0 2 2 2 0 NLS-binding and DNA-binding and dimerisation domains of Nrf1 RRM_1 PF00076.22 AIN98916.1 - 2.6e-21 75.2 0.0 3.5e-21 74.8 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 AIN98916.1 - 3.8e-06 26.5 0.0 6.8e-06 25.7 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 AIN98916.1 - 0.0026 17.6 0.0 0.0049 16.7 0.0 1.5 1 1 0 1 1 1 1 Occluded RNA-recognition motif RRM_1 PF00076.22 AIN98918.1 - 7.9e-18 64.0 0.4 4.4e-17 61.7 0.1 2.2 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 AIN98918.1 - 0.056 13.0 0.0 0.11 12.1 0.0 1.6 1 1 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) ABC_membrane PF00664.23 AIN98919.1 - 3.8e-51 174.3 3.1 5.4e-51 173.8 3.1 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 AIN98919.1 - 1.1e-33 116.6 0.0 2e-33 115.8 0.0 1.4 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 AIN98919.1 - 2.9e-05 23.6 0.1 0.048 13.1 0.0 2.2 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 AIN98919.1 - 0.00023 21.6 0.9 0.0035 17.7 0.9 2.3 1 1 0 1 1 1 1 AAA ATPase domain AAA PF00004.29 AIN98919.1 - 0.00052 20.4 0.1 0.0075 16.7 0.1 2.2 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DEAD PF00270.29 AIN98919.1 - 0.015 15.1 0.0 0.19 11.5 0.0 2.3 2 0 0 2 2 2 0 DEAD/DEAH box helicase AAA_5 PF07728.14 AIN98919.1 - 0.019 15.0 0.2 0.27 11.2 0.1 2.5 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) ABC_ATPase PF09818.9 AIN98919.1 - 0.025 13.4 0.1 0.049 12.4 0.1 1.4 1 0 0 1 1 1 0 Predicted ATPase of the ABC class AAA_22 PF13401.6 AIN98919.1 - 0.027 14.7 1.5 0.22 11.8 0.5 2.7 2 1 1 3 3 3 0 AAA domain AAA_29 PF13555.6 AIN98919.1 - 0.029 14.1 0.0 0.069 12.9 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_15 PF13175.6 AIN98919.1 - 0.041 13.6 0.0 0.063 13.0 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain Zeta_toxin PF06414.12 AIN98919.1 - 0.049 12.9 0.0 0.12 11.6 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin RsgA_GTPase PF03193.16 AIN98919.1 - 0.073 13.0 0.0 0.22 11.4 0.0 1.8 2 0 0 2 2 2 0 RsgA GTPase DUF87 PF01935.17 AIN98919.1 - 0.12 12.4 0.1 0.33 11.0 0.0 1.7 2 0 0 2 2 2 0 Helicase HerA, central domain LSM14 PF12701.7 AIN98920.1 - 2.1e-26 91.8 0.1 3.2e-26 91.2 0.1 1.3 1 0 0 1 1 1 1 Scd6-like Sm domain SM-ATX PF14438.6 AIN98920.1 - 4e-06 26.9 0.0 7.4e-06 26.0 0.0 1.4 1 0 0 1 1 1 1 Ataxin 2 SM domain FDF PF09532.10 AIN98920.1 - 0.00053 20.8 15.7 0.16 12.9 3.5 2.4 1 1 1 2 2 2 2 FDF domain DUF5578 PF17741.1 AIN98921.1 - 3.2e-18 66.1 0.0 2.9e-07 30.2 0.0 3.3 3 0 0 3 3 3 3 Family of unknown function (DUF5578) DnaJ PF00226.31 AIN98922.1 - 0.0076 16.3 0.1 0.018 15.1 0.0 1.6 2 0 0 2 2 2 1 DnaJ domain SP_C-Propep PF08999.10 AIN98922.1 - 0.04 13.7 0.1 0.064 13.0 0.1 1.3 1 0 0 1 1 1 0 Surfactant protein C, N terminal propeptide Y_phosphatase2 PF03162.13 AIN98923.1 - 6.9e-35 120.1 0.0 1.3e-26 93.1 0.0 2.1 2 0 0 2 2 2 2 Tyrosine phosphatase family Y_phosphatase3 PF13350.6 AIN98923.1 - 0.00041 20.4 0.0 0.00057 19.9 0.0 1.2 1 0 0 1 1 1 1 Tyrosine phosphatase family Ins_beta PF03488.14 AIN98924.1 - 0.074 13.1 0.1 0.19 11.8 0.0 1.6 2 0 0 2 2 2 0 Nematode insulin-related peptide beta type Herpes_TK PF00693.18 AIN98924.1 - 0.12 11.6 0.1 0.16 11.2 0.1 1.1 1 0 0 1 1 1 0 Thymidine kinase from herpesvirus PreAtp-grasp PF18604.1 AIN98924.1 - 0.12 12.0 0.0 0.17 11.5 0.0 1.2 1 0 0 1 1 1 0 Pre ATP-grasp domain DUF2475 PF10629.9 AIN98925.1 - 0.051 13.8 1.0 0.13 12.5 1.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2475) Raptor_N PF14538.6 AIN98926.1 - 2.3e-44 150.9 0.0 4.4e-44 150.0 0.0 1.5 1 0 0 1 1 1 1 Raptor N-terminal CASPase like domain HEAT PF02985.22 AIN98926.1 - 0.00023 21.1 1.9 0.11 12.9 0.1 3.4 2 0 0 2 2 2 2 HEAT repeat HEAT_2 PF13646.6 AIN98926.1 - 0.061 13.7 0.0 0.73 10.3 0.0 2.7 1 1 1 2 2 2 0 HEAT repeats NopRA1 PF16201.5 AIN98926.1 - 0.11 12.1 0.1 0.49 9.9 0.1 2.1 2 0 0 2 2 2 0 Nucleolar pre-ribosomal-associated protein 1 Cnd1 PF12717.7 AIN98926.1 - 0.17 11.9 0.5 0.64 10.0 0.2 2.1 2 1 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1 RNA_pol_Rpb2_6 PF00562.28 AIN98927.1 - 1.3e-72 245.0 0.0 1e-71 242.1 0.0 2.1 1 1 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_3 PF04565.16 AIN98927.1 - 3.9e-19 68.6 0.0 1.1e-18 67.2 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_7 PF04560.20 AIN98927.1 - 2.2e-14 53.6 0.0 7.1e-14 52.0 0.0 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpa2_4 PF06883.12 AIN98927.1 - 4.8e-12 45.7 0.0 1.4e-11 44.2 0.0 1.9 1 0 0 1 1 1 1 RNA polymerase I, Rpa2 specific domain RNA_pol_Rpb2_1 PF04563.15 AIN98927.1 - 3.4e-08 33.2 0.0 1.4e-07 31.3 0.0 1.9 2 0 0 2 2 2 1 RNA polymerase beta subunit HetR_C PF18460.1 AIN98927.1 - 0.081 12.9 1.7 0.72 9.8 0.2 2.9 3 0 0 3 3 3 0 Heterocyst differentiation regulator C-terminal Hood domain zinc_ribbon_10 PF10058.9 AIN98927.1 - 0.13 12.0 0.1 0.39 10.5 0.1 1.7 1 0 0 1 1 1 0 Predicted integral membrane zinc-ribbon metal-binding protein PPR PF01535.20 AIN98928.1 - 6.8e-05 22.8 0.2 0.00068 19.7 0.0 2.5 2 0 0 2 2 2 1 PPR repeat PPR_1 PF12854.7 AIN98928.1 - 0.0012 18.5 0.0 0.0039 16.9 0.0 2.0 1 0 0 1 1 1 1 PPR repeat PPR_2 PF13041.6 AIN98928.1 - 0.0021 18.2 0.6 0.014 15.6 0.0 2.6 2 1 1 3 3 3 1 PPR repeat family PPR_3 PF13812.6 AIN98928.1 - 0.0043 17.1 0.0 0.0096 16.0 0.0 1.6 1 0 0 1 1 1 1 Pentatricopeptide repeat domain PPR_long PF17177.4 AIN98928.1 - 0.14 11.5 0.1 0.2 11.0 0.1 1.2 1 0 0 1 1 1 0 Pentacotripeptide-repeat region of PRORP zf-AN1 PF01428.16 AIN98930.1 - 0.033 14.3 28.0 0.038 14.1 8.5 2.5 2 0 0 2 2 2 0 AN1-like Zinc finger ENTH PF01417.20 AIN98932.1 - 1.3e-26 93.0 0.0 2.1e-26 92.4 0.0 1.3 1 0 0 1 1 1 1 ENTH domain CCDC50_N PF15295.6 AIN98932.1 - 0.026 14.7 9.6 0.063 13.4 9.6 1.6 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 50 N-terminus Alpha_kinase PF02816.18 AIN98933.1 - 7.8e-55 185.9 0.0 1.2e-53 182.0 0.0 2.1 2 0 0 2 2 2 1 Alpha-kinase family SCAMP PF04144.13 AIN98937.1 - 1.2e-35 123.4 12.7 1.4e-35 123.1 12.7 1.1 1 0 0 1 1 1 1 SCAMP family SNF2_N PF00176.23 AIN98939.1 - 8.3e-55 185.9 0.1 3.2e-28 98.5 0.0 3.4 2 1 0 2 2 2 2 SNF2 family N-terminal domain Helicase_C PF00271.31 AIN98939.1 - 2.9e-17 63.0 1.1 1.6e-16 60.6 0.0 3.0 4 0 0 4 4 3 1 Helicase conserved C-terminal domain zf-PARP PF00645.18 AIN98939.1 - 6.8e-13 49.3 0.3 2.1e-12 47.7 0.3 1.9 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region zf-RING_2 PF13639.6 AIN98939.1 - 3.4e-05 24.1 3.6 3.4e-05 24.1 3.6 2.9 3 0 0 3 3 2 1 Ring finger domain zf-RING_11 PF17123.5 AIN98939.1 - 0.00013 21.6 2.2 0.00013 21.6 2.2 2.5 2 0 0 2 2 2 1 RING-like zinc finger ERCC3_RAD25_C PF16203.5 AIN98939.1 - 0.00028 20.2 0.0 0.00057 19.2 0.0 1.4 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase zf-C3HC4 PF00097.25 AIN98939.1 - 0.00076 19.3 3.1 0.00076 19.3 3.1 3.3 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 AIN98939.1 - 0.0018 18.1 2.6 0.0018 18.1 2.6 2.7 2 1 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) ResIII PF04851.15 AIN98939.1 - 0.0035 17.4 0.0 0.78 9.7 0.0 2.5 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit zf-rbx1 PF12678.7 AIN98939.1 - 0.049 13.9 2.6 0.22 11.8 2.6 2.2 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 AIN98939.1 - 0.15 12.1 1.4 0.5 10.4 1.4 1.8 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.6 AIN98939.1 - 0.68 10.0 5.6 3 7.9 5.6 2.3 1 0 0 1 1 1 0 RING-type zinc-finger PP2C PF00481.21 AIN98940.1 - 2.9e-50 171.3 0.0 3.7e-50 171.0 0.0 1.1 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 AIN98940.1 - 0.00094 18.9 0.0 0.0016 18.1 0.0 1.4 1 0 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.12 AIN98940.1 - 0.0042 17.0 0.0 0.027 14.4 0.0 2.1 2 0 0 2 2 2 1 Stage II sporulation protein E (SpoIIE) TIP39 PF14980.6 AIN98940.1 - 0.025 14.4 0.0 0.077 12.9 0.0 1.8 1 0 0 1 1 1 0 TIP39 peptide Spore_III_AB PF09548.10 AIN98940.1 - 0.11 12.5 0.0 0.5 10.5 0.0 2.1 2 0 0 2 2 2 0 Stage III sporulation protein AB (spore_III_AB) Mito_fiss_reg PF05308.11 AIN98942.1 - 2.6 8.0 4.1 4.1 7.4 4.1 1.3 1 0 0 1 1 1 0 Mitochondrial fission regulator Pro-rich PF15240.6 AIN98943.1 - 6.1e-05 23.4 15.4 8.4e-05 22.9 15.4 1.3 1 0 0 1 1 1 1 Proline-rich Ank_2 PF12796.7 AIN98944.1 - 5.7e-08 33.2 0.5 0.021 15.4 0.0 4.5 2 2 3 5 5 5 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 AIN98944.1 - 1e-05 26.0 0.8 0.41 11.3 0.0 4.2 3 1 0 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 AIN98944.1 - 0.0014 18.9 0.9 0.2 12.3 0.0 4.1 3 0 0 3 3 3 1 Ankyrin repeat PSCyt3 PF07627.11 AIN98944.1 - 0.12 12.6 0.0 0.34 11.2 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1588) zf-DNL PF05180.12 AIN98945.1 - 9.4e-28 95.9 0.1 1.8e-27 95.1 0.1 1.4 1 0 0 1 1 1 1 DNL zinc finger zf-RING_4 PF14570.6 AIN98945.1 - 0.083 12.7 0.5 0.16 11.8 0.5 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Cyclin_N PF00134.23 AIN98946.1 - 4.9e-07 29.6 0.5 0.00045 20.0 0.0 3.2 3 0 0 3 3 3 2 Cyclin, N-terminal domain TFIIB_C_1 PF18542.1 AIN98946.1 - 0.091 12.8 2.3 0.36 10.9 2.3 2.0 1 0 0 1 1 1 0 Transcription factor IIB C-terminal module 1 Prefoldin_2 PF01920.20 AIN98947.1 - 2.3e-11 43.6 1.3 2.8e-11 43.3 1.3 1.1 1 0 0 1 1 1 1 Prefoldin subunit Prefoldin PF02996.17 AIN98947.1 - 4.4e-05 23.4 1.9 0.0083 16.0 0.4 2.1 2 0 0 2 2 2 2 Prefoldin subunit XhlA PF10779.9 AIN98947.1 - 0.0035 17.5 2.5 0.26 11.5 0.1 2.2 2 0 0 2 2 2 2 Haemolysin XhlA DUF5082 PF16888.5 AIN98947.1 - 0.011 16.1 0.1 0.46 10.8 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF5082) CLZ PF16526.5 AIN98947.1 - 0.025 14.9 2.6 0.58 10.5 0.5 2.2 2 0 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels FapA PF03961.13 AIN98947.1 - 0.039 12.6 0.4 0.047 12.3 0.4 1.0 1 0 0 1 1 1 0 Flagellar Assembly Protein A TPR_MLP1_2 PF07926.12 AIN98947.1 - 0.061 13.4 5.1 0.15 12.1 1.4 2.1 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein PEP-utilisers_N PF05524.13 AIN98947.1 - 0.082 13.1 0.3 0.18 12.0 0.2 1.6 2 0 0 2 2 2 0 PEP-utilising enzyme, N-terminal DUF4140 PF13600.6 AIN98947.1 - 0.092 13.2 4.1 3.9 8.0 0.1 2.1 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) Spc24 PF08286.11 AIN98947.1 - 0.12 12.6 2.5 0.79 10.0 1.0 2.1 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 THOC7 PF05615.13 AIN98947.1 - 0.18 12.1 2.8 0.38 11.0 2.8 1.7 1 1 0 1 1 1 0 Tho complex subunit 7 DivIC PF04977.15 AIN98947.1 - 0.19 11.5 3.0 9.4 6.1 1.1 2.2 2 0 0 2 2 2 0 Septum formation initiator DUF4164 PF13747.6 AIN98947.1 - 2.1 8.7 8.1 39 4.6 8.2 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF4164) PH PF00169.29 AIN98949.1 - 0.0032 17.9 0.1 0.12 12.9 0.0 2.9 2 1 0 2 2 2 1 PH domain Cortex-I_coil PF09304.10 AIN98950.1 - 0.13 12.5 6.3 0.25 11.6 6.3 1.4 1 0 0 1 1 1 0 Cortexillin I, coiled coil RSB_motif PF16294.5 AIN98951.1 - 6.5 7.1 10.4 14 6.0 5.3 2.8 2 0 0 2 2 2 0 RNSP1-SAP18 binding (RSB) motif Kdo PF06293.14 AIN98952.1 - 7e-07 28.8 0.3 0.00012 21.5 0.3 2.2 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 AIN98952.1 - 0.00073 19.2 0.0 0.99 9.0 0.0 2.2 1 1 1 2 2 2 2 RIO1 family Pkinase PF00069.25 AIN98952.1 - 0.016 14.6 0.0 0.044 13.1 0.0 1.7 1 1 0 1 1 1 0 Protein kinase domain LRR_8 PF13855.6 AIN98953.1 - 1.7e-17 62.9 6.7 7.2e-11 41.7 1.3 3.6 2 1 1 3 3 3 2 Leucine rich repeat LRR_4 PF12799.7 AIN98953.1 - 4.3e-10 39.7 4.0 5.9e-05 23.4 0.2 4.0 3 1 1 4 4 4 3 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 AIN98953.1 - 0.0025 17.3 0.0 0.0055 16.2 0.0 1.5 1 0 0 1 1 1 1 Leucine-rich repeat LRR_1 PF00560.33 AIN98953.1 - 0.074 13.6 6.7 0.14 12.8 0.1 4.3 4 1 0 4 4 4 0 Leucine Rich Repeat LRR_6 PF13516.6 AIN98953.1 - 1.2 9.4 3.9 73 3.8 0.1 3.8 3 0 0 3 3 3 0 Leucine Rich repeat PKcGMP_CC PF16808.5 AIN98953.1 - 4.5 7.2 9.2 0.27 11.1 0.2 3.4 3 0 0 3 3 3 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Ribosomal_L23 PF00276.20 AIN98954.1 - 1.5e-06 28.5 0.1 2.5e-06 27.7 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L23 Pro_isomerase PF00160.21 AIN98955.1 - 1.3e-44 152.2 0.0 1.5e-44 152.1 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD SLBP_RNA_bind PF15247.6 AIN98956.1 - 4.2e-18 65.2 0.2 4.2e-18 65.2 0.2 2.5 2 0 0 2 2 2 1 Histone RNA hairpin-binding protein RNA-binding domain Ank_4 PF13637.6 AIN98957.1 - 1.1e-17 64.1 0.9 2e-07 31.4 0.0 2.5 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 AIN98957.1 - 5.3e-15 55.8 0.1 1e-08 35.6 0.0 2.5 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 AIN98957.1 - 2.9e-14 51.8 2.5 5.6e-05 23.2 0.0 4.6 4 0 0 4 4 4 3 Ankyrin repeat Ank PF00023.30 AIN98957.1 - 1.6e-13 50.4 3.9 0.00022 21.5 0.0 4.6 4 0 0 4 4 4 4 Ankyrin repeat Ank_5 PF13857.6 AIN98957.1 - 3.8e-13 49.4 3.4 1.8e-06 28.1 0.1 3.8 2 2 2 4 4 4 4 Ankyrin repeats (many copies) zf-RVT PF13966.6 AIN98957.1 - 0.074 13.8 0.1 0.4 11.4 0.0 2.1 1 1 1 2 2 2 0 zinc-binding in reverse transcriptase PUB PF09409.10 AIN98959.1 - 0.0013 18.6 0.0 0.0025 17.7 0.0 1.4 1 0 0 1 1 1 1 PUB domain Tubulin PF00091.25 AIN98960.1 - 2.2e-67 227.1 0.0 3.3e-67 226.5 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 AIN98960.1 - 3.1e-44 150.2 0.2 5.9e-44 149.3 0.2 1.5 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 AIN98960.1 - 1.1e-05 25.8 0.0 3.3e-05 24.2 0.0 1.9 1 1 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_2 PF13809.6 AIN98960.1 - 0.003 16.8 0.0 0.005 16.1 0.0 1.3 1 0 0 1 1 1 1 Tubulin like Tubulin_3 PF14881.6 AIN98960.1 - 0.04 13.6 0.0 0.098 12.3 0.0 1.6 2 0 0 2 2 2 0 Tubulin domain EF-hand_7 PF13499.6 AIN98961.1 - 1.4e-05 25.4 0.0 0.094 13.2 0.0 4.1 4 0 0 4 4 4 1 EF-hand domain pair EF-hand_6 PF13405.6 AIN98961.1 - 0.0082 16.0 0.0 5.7 7.1 0.0 3.3 4 0 0 4 4 4 2 EF-hand domain EF-hand_8 PF13833.6 AIN98961.1 - 0.24 11.3 0.0 0.68 9.8 0.0 1.8 1 0 0 1 1 1 0 EF-hand domain pair AAA_6 PF12774.7 AIN98962.1 - 2.4e-144 480.3 1.9 2.1e-143 477.2 0.0 2.9 3 0 0 3 3 3 1 Hydrolytic ATP binding site of dynein motor region DHC_N1 PF08385.12 AIN98962.1 - 1e-141 473.4 12.4 1e-141 473.4 12.4 2.9 3 0 0 3 3 3 1 Dynein heavy chain, N-terminal region 1 DHC_N2 PF08393.13 AIN98962.1 - 3.8e-115 385.2 4.4 3.8e-115 385.2 4.4 3.7 4 0 0 4 4 4 1 Dynein heavy chain, N-terminal region 2 AAA_8 PF12780.7 AIN98962.1 - 3.2e-87 292.1 0.0 9.2e-87 290.6 0.0 1.9 1 0 0 1 1 1 1 P-loop containing dynein motor region D4 Dynein_C PF18199.1 AIN98962.1 - 1.4e-77 261.0 0.1 8.4e-77 258.4 0.0 2.4 2 0 0 2 2 2 1 Dynein heavy chain C-terminal domain AAA_9 PF12781.7 AIN98962.1 - 9.4e-76 253.8 7.3 9.4e-76 253.8 7.3 2.6 3 0 0 3 3 3 1 ATP-binding dynein motor region AAA_7 PF12775.7 AIN98962.1 - 2.7e-53 180.1 5.4 4.3e-50 169.7 0.1 5.0 5 0 0 5 5 5 2 P-loop containing dynein motor region AAA_lid_11 PF18198.1 AIN98962.1 - 4.9e-45 153.3 0.1 8e-44 149.3 0.1 2.7 2 0 0 2 2 2 1 Dynein heavy chain AAA lid domain Dynein_heavy PF03028.15 AIN98962.1 - 1.1e-37 128.8 2.2 2.9e-36 124.1 0.1 3.5 3 0 0 3 3 2 1 Dynein heavy chain region D6 P-loop domain MT PF12777.7 AIN98962.1 - 2.2e-37 128.9 8.5 2.2e-37 128.9 8.5 1.7 2 0 0 2 2 2 1 Microtubule-binding stalk of dynein motor Dynein_AAA_lid PF17852.1 AIN98962.1 - 5.2e-20 71.8 0.2 3.6e-19 69.1 0.2 2.6 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain AAA_5 PF07728.14 AIN98962.1 - 4e-15 56.0 0.0 0.0016 18.5 0.0 5.7 4 1 0 4 4 4 3 AAA domain (dynein-related subfamily) AAA_lid_1 PF17857.1 AIN98962.1 - 3.4e-11 43.2 0.0 6.8e-10 39.1 0.0 3.1 1 1 0 1 1 1 1 AAA+ lid domain AAA PF00004.29 AIN98962.1 - 2.2e-07 31.4 1.2 0.038 14.4 0.0 5.5 5 0 0 5 5 5 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 AIN98962.1 - 1.8e-05 25.2 1.0 5.1 7.4 0.0 6.2 6 0 0 6 6 6 1 AAA ATPase domain AAA_18 PF13238.6 AIN98962.1 - 0.0065 17.0 0.0 0.24 12.0 0.0 3.7 3 0 0 3 3 3 1 AAA domain PET PF06297.14 AIN98962.1 - 0.054 13.8 0.1 0.23 11.8 0.1 2.2 1 0 0 1 1 1 0 PET Domain SNF5 PF04855.12 AIN98962.1 - 0.07 12.9 4.3 3.4 7.4 0.1 3.4 3 0 0 3 3 3 0 SNF5 / SMARCB1 / INI1 AAA_22 PF13401.6 AIN98962.1 - 0.23 11.8 8.0 24 5.2 0.0 5.7 6 0 0 6 6 6 0 AAA domain Complex1_LYR PF05347.15 AIN98963.1 - 0.00029 20.8 0.0 0.00063 19.7 0.0 1.6 1 1 0 1 1 1 1 Complex 1 protein (LYR family) 2OG-FeII_Oxy PF03171.20 AIN98965.1 - 8.5e-15 55.1 0.0 1.8e-14 54.0 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.6 AIN98965.1 - 0.0079 16.9 0.0 1.4 9.7 0.0 2.5 2 0 0 2 2 2 2 non-haem dioxygenase in morphine synthesis N-terminal PrlF_antitoxin PF15937.5 AIN98965.1 - 0.059 13.8 0.0 0.11 12.9 0.0 1.4 1 0 0 1 1 1 0 prlF antitoxin for toxin YhaV_toxin SecE PF00584.20 AIN98966.1 - 1.4e-12 47.3 0.2 1.7e-12 47.1 0.2 1.1 1 0 0 1 1 1 1 SecE/Sec61-gamma subunits of protein translocation complex NAD_binding_2 PF03446.15 AIN98967.1 - 1.8e-29 102.9 0.0 3e-29 102.2 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 AIN98967.1 - 8.3e-13 48.6 0.2 2.1e-11 44.1 0.1 2.5 2 0 0 2 2 2 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase Shikimate_DH PF01488.20 AIN98967.1 - 7.2e-05 22.9 0.3 0.0044 17.1 0.1 2.2 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase F420_oxidored PF03807.17 AIN98967.1 - 0.0066 17.0 0.1 0.051 14.2 0.0 2.3 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent GFO_IDH_MocA PF01408.22 AIN98967.1 - 0.0085 16.9 0.0 1.1 10.1 0.0 2.9 2 1 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold 3HCDH_N PF02737.18 AIN98967.1 - 0.12 12.3 0.0 0.22 11.4 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain RcsD_ABL PF16359.5 AIN98967.1 - 0.18 11.9 0.0 0.41 10.8 0.0 1.5 1 0 0 1 1 1 0 RcsD-ABL domain BBP1_C PF15272.6 AIN98969.1 - 0.055 13.3 0.5 0.11 12.3 0.5 1.6 1 0 0 1 1 1 0 Spindle pole body component BBP1, C-terminal Frataxin_Cyay PF01491.16 AIN98970.1 - 3.9e-28 97.7 0.0 5.8e-28 97.1 0.0 1.3 1 0 0 1 1 1 1 Frataxin-like domain Inhibitor_I42 PF09394.10 AIN98972.1 - 0.34 11.4 2.0 13 6.2 0.4 3.6 2 1 1 3 3 3 0 Chagasin family peptidase inhibitor I42 Lge1 PF11488.8 AIN98972.1 - 4.9 7.4 9.0 39 4.5 1.5 2.6 1 1 1 2 2 2 0 Transcriptional regulatory protein LGE1 AATF-Che1 PF13339.6 AIN98973.1 - 0.0073 17.0 1.6 0.0073 17.0 1.6 2.7 3 1 0 3 3 3 1 Apoptosis antagonizing transcription factor PsbP PF01789.16 AIN98973.1 - 0.034 14.3 0.2 0.082 13.0 0.2 1.6 1 0 0 1 1 1 0 PsbP RRM_1 PF00076.22 AIN98974.1 - 0.0014 18.4 0.1 0.0029 17.4 0.1 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF2652 PF10851.8 AIN98974.1 - 0.021 14.9 0.0 0.043 13.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2652) CorA PF01544.18 AIN98975.1 - 3e-19 69.4 0.0 1.1e-18 67.6 0.0 1.7 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein DnaJ_C PF01556.18 AIN98976.1 - 2.2e-33 115.4 0.0 2.9e-33 115.1 0.0 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 AIN98976.1 - 8.2e-16 57.9 0.1 1.3e-15 57.2 0.1 1.3 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 AIN98976.1 - 1.9e-13 50.6 12.8 3.1e-13 49.9 12.8 1.4 1 0 0 1 1 1 1 DnaJ central domain Anti-TRAP PF15777.5 AIN98976.1 - 8.9e-08 32.0 7.6 0.00093 19.1 1.0 2.4 2 0 0 2 2 2 2 Tryptophan RNA-binding attenuator protein inhibitory protein T6SS_TssF PF05947.12 AIN98976.1 - 0.018 13.6 0.0 0.025 13.1 0.0 1.1 1 0 0 1 1 1 0 Type VI secretion system, TssF HypA PF01155.19 AIN98976.1 - 0.092 12.8 10.7 1.4 9.0 2.1 2.3 1 1 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA TackOD1 PF18551.1 AIN98976.1 - 0.12 12.1 0.3 0.12 12.1 0.3 2.2 1 1 1 2 2 2 0 Thaumarchaeal output domain 1 DZR PF12773.7 AIN98976.1 - 0.32 11.1 11.3 0.52 10.4 1.6 2.2 1 1 2 3 3 3 0 Double zinc ribbon PHF5 PF03660.14 AIN98976.1 - 0.45 10.7 5.3 1 9.6 5.3 1.6 1 1 0 1 1 1 0 PHF5-like protein Lar_restr_allev PF14354.6 AIN98976.1 - 0.46 10.9 9.0 22 5.5 0.5 3.5 2 1 1 3 3 3 0 Restriction alleviation protein Lar zinc_ribbon_9 PF14369.6 AIN98976.1 - 0.52 10.6 12.8 3.9 7.8 0.3 3.5 2 2 1 3 3 3 0 zinc-ribbon zf-ribbon_3 PF13248.6 AIN98976.1 - 0.69 9.4 12.4 1.8 8.1 0.2 3.6 4 0 0 4 4 4 0 zinc-ribbon domain Zn_ribbon_SprT PF17283.2 AIN98976.1 - 0.86 9.6 12.7 2.3 8.2 4.7 3.5 2 1 0 2 2 2 0 SprT-like zinc ribbon domain Prok-RING_1 PF14446.6 AIN98976.1 - 1.1 9.3 11.3 0.43 10.6 1.0 2.5 2 1 0 2 2 2 0 Prokaryotic RING finger family 1 zf-Mss51 PF13824.6 AIN98976.1 - 1.3 9.1 8.7 0.38 10.9 3.5 2.3 2 0 0 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 DUF1356 PF07092.12 AIN98976.1 - 1.6 8.0 5.5 1 8.5 0.5 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1356) zf-RING_7 PF02591.15 AIN98976.1 - 2.3 8.5 6.5 1.3 9.2 0.2 3.0 3 0 0 3 3 3 0 C4-type zinc ribbon domain zf_CopZ PF18423.1 AIN98976.1 - 3 7.9 14.7 2.4 8.2 0.2 3.6 3 1 1 4 4 3 0 Zinc binding domain DUF1272 PF06906.11 AIN98976.1 - 7.4 6.7 10.1 10 6.3 3.6 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF1272) zf-C4_Topoisom PF01396.19 AIN98976.1 - 8.2 6.3 11.7 8.3 6.3 0.3 3.3 3 0 0 3 3 3 0 Topoisomerase DNA binding C4 zinc finger OrfB_Zn_ribbon PF07282.11 AIN98976.1 - 9 6.3 7.9 27 4.8 0.4 2.4 2 0 0 2 2 2 0 Putative transposase DNA-binding domain Kelch_1 PF01344.25 AIN98977.1 - 2.3e-05 23.9 0.1 0.13 11.9 0.1 3.0 2 0 0 2 2 2 2 Kelch motif Kelch_6 PF13964.6 AIN98977.1 - 0.00012 22.3 0.0 0.11 12.8 0.0 3.1 2 0 0 2 2 2 2 Kelch motif Kelch_4 PF13418.6 AIN98977.1 - 0.00034 20.5 7.6 0.082 12.9 0.0 4.1 4 0 0 4 4 4 2 Galactose oxidase, central domain Orbi_VP6 PF01516.16 AIN98977.1 - 0.024 14.1 0.5 0.067 12.7 0.5 1.7 1 0 0 1 1 1 0 Orbivirus helicase VP6 Kelch_5 PF13854.6 AIN98977.1 - 0.031 14.3 3.3 15 5.7 0.0 3.8 3 0 0 3 3 3 0 Kelch motif Kelch_3 PF13415.6 AIN98977.1 - 1 9.7 13.3 0.2 12.0 0.1 5.9 5 0 0 5 5 5 0 Galactose oxidase, central domain Aldedh PF00171.22 AIN98978.1 - 1.9e-176 587.1 0.6 2.1e-176 587.0 0.6 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.11 AIN98978.1 - 0.12 11.8 0.0 0.25 10.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1487) LPD7 PF18821.1 AIN98978.1 - 0.17 12.0 0.6 0.97 9.6 0.1 2.2 2 0 0 2 2 2 0 Large polyvalent protein-associated domain 7 SBP_bac_3 PF00497.20 AIN98979.1 - 0.049 13.1 0.0 2.2 7.7 0.0 2.0 2 0 0 2 2 2 0 Bacterial extracellular solute-binding proteins, family 3 SMI1_KNR4 PF09346.10 AIN98980.1 - 0.004 17.6 0.0 0.011 16.1 0.0 1.7 2 0 0 2 2 2 1 SMI1 / KNR4 family (SUKH-1) Acetyltransf_16 PF05301.11 AIN98981.1 - 1.3e-49 168.3 0.0 1.6e-49 168.0 0.0 1.1 1 0 0 1 1 1 1 GNAT acetyltransferase, Mec-17 Acetyltransf_7 PF13508.7 AIN98981.1 - 0.00014 22.2 0.0 0.00032 21.0 0.0 1.8 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 AIN98981.1 - 0.00036 20.8 0.0 0.00066 19.9 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 AIN98981.1 - 0.0032 17.4 0.0 0.0085 16.0 0.0 1.8 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain LMBR1 PF04791.16 AIN98982.1 - 2.6e-32 112.4 33.9 2.3e-22 79.6 12.7 2.1 1 1 1 2 2 2 2 LMBR1-like membrane protein ATP-synt_ab PF00006.25 AIN98983.1 - 7e-64 215.4 0.1 2.7e-63 213.5 0.0 1.9 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N PF02874.23 AIN98983.1 - 2.7e-13 50.2 0.2 6.6e-13 49.0 0.2 1.7 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain AAA PF00004.29 AIN98983.1 - 0.0046 17.4 0.1 0.029 14.8 0.0 2.2 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.6 AIN98983.1 - 0.016 15.5 1.5 0.27 11.5 0.4 2.4 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.6 AIN98983.1 - 0.018 14.6 0.2 0.095 12.3 0.0 2.0 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.22 AIN98983.1 - 0.033 13.4 0.1 0.071 12.3 0.1 1.6 1 0 0 1 1 1 0 NB-ARC domain ATPase PF06745.13 AIN98983.1 - 0.036 13.4 0.1 0.062 12.6 0.1 1.4 1 0 0 1 1 1 0 KaiC RsgA_GTPase PF03193.16 AIN98983.1 - 0.07 13.0 0.0 0.15 11.9 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase ATPase_2 PF01637.18 AIN98983.1 - 0.1 12.5 0.1 0.25 11.2 0.0 1.6 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea Ribosomal_S25 PF03297.15 AIN98984.1 - 8.1e-36 122.3 4.9 9.4e-36 122.1 4.9 1.1 1 0 0 1 1 1 1 S25 ribosomal protein DNA_methylase PF00145.17 AIN98985.1 - 3e-39 135.3 0.0 3.7e-30 105.4 0.0 3.6 2 1 0 2 2 2 2 C-5 cytosine-specific DNA methylase Lysis_col PF02402.16 AIN98985.1 - 2.8 7.7 4.1 8.9 6.1 0.3 2.8 2 0 0 2 2 2 0 Lysis protein zinc_ribbon_16 PF17034.5 AIN98989.1 - 3.4e-08 33.8 13.9 3.4e-08 33.8 13.9 2.1 2 1 0 2 2 2 1 Zinc-ribbon like family Zn_ribbon_17 PF17120.5 AIN98989.1 - 0.0023 17.5 14.0 0.0064 16.1 14.0 1.8 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-RING_2 PF13639.6 AIN98989.1 - 3.4 8.1 13.1 0.49 10.8 7.7 2.5 2 0 0 2 2 2 0 Ring finger domain zinc_ribbon_16 PF17034.5 AIN98990.1 - 0.0023 18.1 23.6 0.024 14.8 23.6 2.3 1 1 0 1 1 1 1 Zinc-ribbon like family AKNA PF12443.8 AIN98991.1 - 0.077 13.6 0.1 0.53 11.0 0.0 2.4 2 0 0 2 2 2 0 AT-hook-containing transcription factor Cullin PF00888.22 AIN98992.1 - 2.8e-49 168.3 0.0 1e-48 166.4 0.0 1.7 1 1 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 AIN98992.1 - 4.3e-07 29.9 0.0 1.1e-06 28.6 0.0 1.7 1 0 0 1 1 1 1 Cullin protein neddylation domain NPL4 PF05021.15 AIN98993.1 - 2.4e-14 53.4 0.0 6.7e-08 32.2 0.0 2.6 2 1 0 2 2 2 2 NPL4 family PRP38 PF03371.15 AIN98994.1 - 5e-05 23.2 0.0 8.9e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 PRP38 family MbeB_N PF04837.12 AIN98994.1 - 0.14 12.5 0.0 0.82 10.0 0.0 2.2 2 0 0 2 2 2 0 MbeB-like, N-term conserved region PPP4R2 PF09184.11 AIN98995.1 - 2.3e-05 24.1 0.0 3.5e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 PPP4R2 RNA_pol_N PF01194.17 AIN98996.1 - 1.3e-29 102.3 0.7 1.5e-29 102.0 0.7 1.1 1 0 0 1 1 1 1 RNA polymerases N / 8 kDa subunit UBA PF00627.31 AIN98996.1 - 0.078 12.9 0.0 0.13 12.2 0.0 1.3 1 0 0 1 1 1 0 UBA/TS-N domain Metallophos PF00149.28 AIN98997.1 - 1.4e-33 117.2 1.1 1.9e-33 116.7 1.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase KptA_kDCL PF18176.1 AIN98998.1 - 2.3e-52 177.2 0.1 6.8e-52 175.7 0.1 1.9 1 0 0 1 1 1 1 KptA in kinetoplastid DICER domain La_HTH_kDCL PF18177.1 AIN98998.1 - 1.6e-26 92.4 0.1 4.4e-26 91.0 0.1 1.8 1 0 0 1 1 1 1 La HTH in kinetoplastid DICER domain Ribonuclease_3 PF00636.26 AIN98998.1 - 0.04 14.6 0.1 0.78 10.4 0.0 2.8 2 1 0 2 2 2 0 Ribonuclease III domain GIY-YIG PF01541.24 AIN98999.1 - 1e-10 41.7 0.0 1.8e-10 40.9 0.0 1.4 1 0 0 1 1 1 1 GIY-YIG catalytic domain YacG PF03884.14 AIN98999.1 - 7.3 6.4 6.7 0.94 9.3 0.8 2.3 2 0 0 2 2 2 0 DNA gyrase inhibitor YacG Sec23_trunk PF04811.15 AIN99000.1 - 1.3e-37 129.7 0.0 2.3e-37 128.9 0.0 1.4 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.15 AIN99000.1 - 4.1e-21 74.7 0.0 7.2e-21 73.9 0.0 1.4 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.12 AIN99000.1 - 8.3e-17 61.7 0.2 1.5e-16 60.9 0.2 1.5 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.15 AIN99000.1 - 1.7e-11 43.9 0.7 4.2e-11 42.7 0.7 1.7 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger ASH PF15780.5 AIN99001.1 - 7.9e-08 32.4 2.4 0.00083 19.5 0.1 5.4 5 0 0 5 5 5 2 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin fn3_5 PF06280.12 AIN99001.1 - 0.15 12.8 0.2 5 7.9 0.0 3.6 3 0 0 3 3 3 0 Fn3-like domain TAP42 PF04177.12 AIN99003.1 - 2.5e-45 155.0 4.5 3.5e-44 151.2 4.5 2.0 1 1 0 1 1 1 1 TAP42-like family ATP_bind_1 PF03029.17 AIN99005.1 - 7.9e-50 169.9 0.0 8.9e-50 169.7 0.0 1.0 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein Arm PF00514.23 AIN99005.1 - 0.12 12.5 0.1 0.55 10.4 0.0 2.2 2 0 0 2 2 2 0 Armadillo/beta-catenin-like repeat Surp PF01805.20 AIN99006.1 - 5.3e-13 48.7 0.5 1.6e-09 37.6 0.0 2.4 2 0 0 2 2 2 2 Surp module DNA_pol_D_N PF18018.1 AIN99007.1 - 1.4e-24 86.7 0.0 2.8e-24 85.7 0.0 1.5 1 0 0 1 1 1 1 DNA polymerase delta subunit OB-fold domain DNA_pol_E_B PF04042.16 AIN99007.1 - 4.6e-24 85.0 0.7 6.4e-22 77.9 0.7 2.2 1 1 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B Ras PF00071.22 AIN99008.1 - 2.1e-50 170.5 0.0 2.6e-50 170.2 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 AIN99008.1 - 6.3e-32 110.3 0.0 1.1e-31 109.5 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 AIN99008.1 - 5.2e-11 42.3 0.0 6.9e-11 41.9 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 AIN99008.1 - 0.00027 20.3 0.0 0.00037 19.9 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RNA_helicase PF00910.22 AIN99008.1 - 0.00033 21.0 0.2 0.0021 18.4 0.2 2.0 1 1 0 1 1 1 1 RNA helicase MMR_HSR1 PF01926.23 AIN99008.1 - 0.00033 20.7 0.0 0.00054 20.0 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 AIN99008.1 - 0.0081 16.1 0.0 2.9 7.8 0.0 2.3 2 0 0 2 2 2 2 RsgA GTPase G-alpha PF00503.20 AIN99008.1 - 0.0092 15.2 1.1 1.3 8.1 0.1 2.7 2 1 1 3 3 3 1 G-protein alpha subunit GTP_EFTU PF00009.27 AIN99008.1 - 0.019 14.5 0.5 0.075 12.6 0.0 1.9 1 1 1 2 2 2 0 Elongation factor Tu GTP binding domain AAA_7 PF12775.7 AIN99008.1 - 0.029 13.9 0.0 0.045 13.3 0.0 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_33 PF13671.6 AIN99008.1 - 0.037 14.2 0.0 0.054 13.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain Pox_A32 PF04665.12 AIN99008.1 - 0.041 13.4 0.0 0.072 12.5 0.0 1.4 1 0 0 1 1 1 0 Poxvirus A32 protein cobW PF02492.19 AIN99008.1 - 0.077 12.6 0.1 3.7 7.1 0.1 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_16 PF13191.6 AIN99008.1 - 0.081 13.3 0.0 0.15 12.4 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain AAA_24 PF13479.6 AIN99008.1 - 0.098 12.4 0.1 0.13 11.9 0.1 1.3 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 AIN99008.1 - 0.098 12.7 0.0 0.2 11.6 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Septin PF00735.18 AIN99008.1 - 0.1 11.8 0.0 0.16 11.3 0.0 1.3 1 0 0 1 1 1 0 Septin Cluap1 PF10234.9 AIN99009.1 - 8.6e-91 304.0 14.6 1.2e-90 303.6 14.6 1.2 1 0 0 1 1 1 1 Clusterin-associated protein-1 Lectin_N PF03954.14 AIN99009.1 - 2.9 7.6 6.8 0.56 10.0 1.0 2.4 2 1 0 2 2 2 0 Hepatic lectin, N-terminal domain RNase_T PF00929.24 AIN99010.1 - 2.6e-06 28.1 0.0 4.1e-06 27.4 0.0 1.3 1 0 0 1 1 1 1 Exonuclease DUF1295 PF06966.12 AIN99012.1 - 5.5e-09 35.9 1.8 7.6e-09 35.4 0.5 1.8 1 1 0 2 2 2 1 Protein of unknown function (DUF1295) PEMT PF04191.13 AIN99012.1 - 9.3e-05 22.8 0.8 0.00023 21.5 0.6 1.8 1 1 0 1 1 1 1 Phospholipid methyltransferase Steroid_dh PF02544.16 AIN99012.1 - 0.0034 17.4 1.8 0.0037 17.3 0.6 1.7 1 1 1 2 2 2 1 3-oxo-5-alpha-steroid 4-dehydrogenase ICMT PF04140.14 AIN99012.1 - 0.071 13.5 0.9 0.17 12.4 0.1 2.1 3 0 0 3 3 3 0 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PCRF PF03462.18 AIN99013.1 - 1.8e-28 99.7 0.1 1.8e-28 99.7 0.1 1.8 2 0 0 2 2 2 1 PCRF domain RF-1 PF00472.20 AIN99013.1 - 7e-26 90.4 0.1 1.5e-25 89.3 0.1 1.6 1 0 0 1 1 1 1 RF-1 domain UL141 PF16758.5 AIN99013.1 - 0.068 12.9 0.0 0.13 12.0 0.0 1.4 1 0 0 1 1 1 0 Herpes-like virus membrane glycoprotein UL141 DUF1126 PF06565.12 AIN99014.1 - 2e-68 226.9 0.3 3.1e-25 88.0 0.0 3.4 3 0 0 3 3 3 3 DUF1126 PH-like domain EF-hand_7 PF13499.6 AIN99014.1 - 0.0022 18.4 0.6 0.49 10.9 0.0 3.1 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.32 AIN99014.1 - 0.16 11.6 0.5 23 4.8 0.0 3.1 3 0 0 3 3 3 0 EF hand Cyclin_N PF00134.23 AIN99015.1 - 1.2e-36 125.3 0.3 2.4e-36 124.3 0.3 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 AIN99015.1 - 2.6e-14 53.3 0.0 4.5e-14 52.6 0.0 1.3 1 0 0 1 1 1 1 Cyclin, C-terminal domain NfI_DNAbd_pre-N PF10524.9 AIN99015.1 - 0.05 13.5 0.0 0.11 12.4 0.0 1.6 1 0 0 1 1 1 0 Nuclear factor I protein pre-N-terminus Peptidase_C2 PF00648.21 AIN99017.1 - 3e-63 213.6 0.1 5.2e-63 212.8 0.1 1.4 1 0 0 1 1 1 1 Calpain family cysteine protease DUF1935 PF09149.10 AIN99017.1 - 6.4e-25 87.5 0.2 1.5e-24 86.3 0.2 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1935) Glyco_transf_92 PF01697.27 AIN99017.1 - 0.0059 16.3 0.8 0.019 14.7 0.8 1.8 1 0 0 1 1 1 1 Glycosyltransferase family 92 Calpain_III PF01067.22 AIN99017.1 - 0.023 14.9 1.1 0.032 14.5 0.1 1.8 2 0 0 2 2 2 0 Calpain large subunit, domain III M60-like_N PF17291.2 AIN99017.1 - 0.1 12.5 0.1 0.44 10.5 0.0 2.1 2 0 0 2 2 2 0 N-terminal domain of M60-like peptidases Rab3-GTPase_cat PF13890.6 AIN99018.1 - 1.8e-41 141.5 0.1 3.6e-41 140.5 0.1 1.5 1 0 0 1 1 1 1 Rab3 GTPase-activating protein catalytic subunit Methyltr_RsmB-F PF01189.17 AIN99019.1 - 1.2e-22 80.6 0.2 6.6e-16 58.5 0.0 2.3 2 0 0 2 2 2 2 16S rRNA methyltransferase RsmB/F PUA PF01472.20 AIN99019.1 - 3.2e-06 27.0 0.2 6.3e-06 26.1 0.2 1.4 1 0 0 1 1 1 1 PUA domain Pkinase PF00069.25 AIN99021.1 - 1.6e-42 145.7 0.0 2.2e-42 145.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 AIN99021.1 - 7e-30 104.2 0.0 1e-29 103.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 AIN99021.1 - 2.7e-06 26.4 0.0 4.4e-06 25.7 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 AIN99021.1 - 0.00027 20.4 0.0 0.00039 19.8 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 AIN99021.1 - 0.022 14.7 2.3 0.091 12.7 0.0 2.5 2 1 1 3 3 3 0 Phosphotransferase enzyme family ABC_ATPase PF09818.9 AIN99023.1 - 1.8e-169 564.3 0.0 2.3e-169 563.9 0.0 1.1 1 0 0 1 1 1 1 Predicted ATPase of the ABC class AAA_23 PF13476.6 AIN99023.1 - 0.0034 17.9 0.0 0.0057 17.2 0.0 1.2 1 0 0 1 1 1 1 AAA domain zf-Tim10_DDP PF02953.15 AIN99024.1 - 0.0016 18.1 0.2 0.0028 17.3 0.2 1.5 1 1 0 1 1 1 1 Tim10/DDP family zinc finger Pkinase PF00069.25 AIN99025.1 - 1.9e-25 89.7 0.0 6.2e-14 52.0 0.0 3.5 3 1 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 AIN99025.1 - 4.8e-06 26.0 0.0 0.8 8.9 0.0 3.1 3 0 0 3 3 3 3 Protein tyrosine kinase Pox_ser-thr_kin PF05445.11 AIN99025.1 - 0.24 10.3 0.1 0.37 9.7 0.1 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase TRAPPC-Trs85 PF12739.7 AIN99026.1 - 3e-33 115.4 0.1 6.1e-33 114.4 0.1 1.5 1 0 0 1 1 1 1 ER-Golgi trafficking TRAPP I complex 85 kDa subunit Pkinase PF00069.25 AIN99027.1 - 3e-25 89.1 0.0 8.7e-20 71.2 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 AIN99027.1 - 1.6e-12 47.2 0.0 3e-08 33.3 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 AIN99027.1 - 4.2e-06 25.8 0.0 6.1e-06 25.3 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 AIN99027.1 - 0.029 14.3 0.1 0.1 12.5 0.0 1.8 2 0 0 2 2 2 0 Phosphotransferase enzyme family BRCT PF00533.26 AIN99028.1 - 0.0031 17.8 0.0 0.17 12.2 0.0 2.7 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 AIN99028.1 - 0.013 15.8 0.0 0.45 11.0 0.0 3.0 3 0 0 3 3 3 0 BRCT domain, a BRCA1 C-terminus domain WD40 PF00400.32 AIN99029.1 - 5.5e-15 55.5 13.8 1.6 9.8 0.1 9.9 9 0 0 9 9 9 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 AIN99029.1 - 1.4e-06 28.5 0.2 0.052 13.8 0.0 4.4 5 1 1 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 AIN99029.1 - 0.13 11.2 0.1 0.34 9.8 0.1 1.6 1 0 0 1 1 1 0 WD40 region of Ge1, enhancer of mRNA-decapping protein JAB PF01398.21 AIN99030.1 - 0.00011 22.1 0.0 0.00031 20.7 0.0 1.8 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease DUF2150 PF09920.9 AIN99030.1 - 0.0074 16.3 0.1 0.011 15.7 0.1 1.2 1 0 0 1 1 1 1 Uncharacterized protein conserved in archaea (DUF2150) UPF0172 PF03665.13 AIN99030.1 - 0.037 14.1 0.4 0.097 12.7 0.0 1.8 2 1 0 2 2 2 0 Uncharacterised protein family (UPF0172) GIT_SHD PF08518.11 AIN99030.1 - 1.1 9.0 7.9 3.8 7.2 0.2 3.6 4 0 0 4 4 4 0 Spa2 homology domain (SHD) of GIT DAGAT PF03982.13 AIN99032.1 - 2.4e-73 246.7 0.0 3e-73 246.3 0.0 1.1 1 0 0 1 1 1 1 Diacylglycerol acyltransferase SSFA2_C PF14723.6 AIN99032.1 - 0.14 12.0 0.2 0.27 11.1 0.2 1.5 1 0 0 1 1 1 0 Sperm-specific antigen 2 C-terminus DUF1016_N PF17761.1 AIN99033.1 - 0.003 17.7 0.1 0.014 15.6 0.0 1.9 2 0 0 2 2 2 1 DUF1016 N-terminal domain ribosomal_L24 PF17136.4 AIN99033.1 - 0.012 16.0 0.1 0.025 15.0 0.1 1.6 1 0 0 1 1 1 0 Ribosomal proteins 50S L24/mitochondrial 39S L24 KOW PF00467.29 AIN99033.1 - 0.022 14.7 1.0 0.055 13.4 1.0 1.7 1 0 0 1 1 1 0 KOW motif CHCH PF06747.13 AIN99034.1 - 0.0013 18.8 3.9 0.11 12.7 0.5 2.4 2 0 0 2 2 2 2 CHCH domain CX9C PF16860.5 AIN99034.1 - 0.041 13.9 0.2 0.041 13.9 0.2 2.2 2 0 0 2 2 2 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, EFP_N PF08207.12 AIN99035.1 - 9.8e-06 25.5 0.4 1.7e-05 24.7 0.4 1.4 1 0 0 1 1 1 1 Elongation factor P (EF-P) KOW-like domain HORMA PF02301.18 AIN99037.1 - 4.3e-16 59.1 0.0 7.1e-16 58.4 0.0 1.3 1 1 0 1 1 1 1 HORMA domain VWA_3 PF13768.6 AIN99037.1 - 0.064 13.2 0.0 0.094 12.7 0.0 1.3 1 0 0 1 1 1 0 von Willebrand factor type A domain bacHORMA_2 PF18173.1 AIN99037.1 - 0.096 12.5 0.6 0.21 11.4 0.0 1.8 2 1 0 2 2 2 0 Bacterial HORMA domain 2 TPR_12 PF13424.6 AIN99038.1 - 9.1e-16 57.9 24.9 1e-06 29.0 4.6 6.1 5 0 0 5 5 5 5 Tetratricopeptide repeat TPR_2 PF07719.17 AIN99038.1 - 2.7e-05 24.0 11.5 0.47 10.7 0.1 5.4 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_8 PF13181.6 AIN99038.1 - 0.64 10.4 1.9 3 8.3 0.1 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.28 AIN99038.1 - 4.2 7.3 9.1 51 3.9 0.6 4.5 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_7 PF13176.6 AIN99038.1 - 4.6 7.5 5.2 12 6.2 0.1 3.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.6 AIN99038.1 - 5.5 7.8 13.3 9.2 7.2 0.7 4.9 4 0 0 4 4 4 0 Tetratricopeptide repeat AAA_33 PF13671.6 AIN99038.1 - 5.9 7.0 6.5 3.5 7.8 3.8 2.1 2 0 0 2 2 2 0 AAA domain HSCB_C PF07743.13 AIN99039.1 - 0.0064 16.9 0.0 0.15 12.6 0.0 2.5 2 0 0 2 2 2 1 HSCB C-terminal oligomerisation domain DnaJ PF00226.31 AIN99039.1 - 0.014 15.6 1.4 0.095 12.8 0.2 2.5 2 0 0 2 2 2 0 DnaJ domain LRR_9 PF14580.6 AIN99040.1 - 8.7e-13 48.1 0.0 1.5e-12 47.4 0.0 1.3 1 0 0 1 1 1 1 Leucine-rich repeat LRR_4 PF12799.7 AIN99040.1 - 1.5e-08 34.8 4.5 8.6e-05 22.8 0.4 2.8 1 1 2 3 3 3 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 AIN99040.1 - 1.6e-07 30.9 3.1 3.6e-07 29.8 3.1 1.6 1 0 0 1 1 1 1 Leucine rich repeat LRR_6 PF13516.6 AIN99040.1 - 8.9e-05 22.3 2.3 1.1 9.5 0.0 3.5 3 0 0 3 3 3 2 Leucine Rich repeat DUF3349 PF11829.8 AIN99040.1 - 0.044 14.6 0.0 0.16 12.8 0.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3349) LRR_1 PF00560.33 AIN99040.1 - 0.24 12.1 0.6 89 4.3 0.1 3.4 2 1 1 3 3 3 0 Leucine Rich Repeat LSM PF01423.22 AIN99041.1 - 2.6e-14 52.7 0.0 3.5e-14 52.2 0.0 1.2 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 AIN99041.1 - 0.019 15.1 0.2 0.19 11.9 0.2 2.0 1 1 0 1 1 1 0 Ataxin 2 SM domain Transket_pyr PF02779.24 AIN99042.1 - 7.1e-45 152.9 0.1 1e-44 152.3 0.1 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 AIN99042.1 - 1.7e-39 134.5 0.0 4.6e-39 133.1 0.0 1.8 1 0 0 1 1 1 1 Transketolase, C-terminal domain PFOR_II PF17147.4 AIN99042.1 - 0.08 13.3 0.0 0.46 10.8 0.0 2.3 2 0 0 2 2 2 0 Pyruvate:ferredoxin oxidoreductase core domain II Glyco_transf_5 PF08323.11 AIN99043.1 - 0.12 12.0 0.2 0.35 10.5 0.2 1.7 1 0 0 1 1 1 0 Starch synthase catalytic domain DUF1935 PF09149.10 AIN99046.1 - 2.3e-27 95.4 0.0 2.7e-27 95.1 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1935) RMI1_N PF08585.12 AIN99047.1 - 1.1e-09 38.4 0.2 4.9e-09 36.3 0.2 1.9 1 1 0 1 1 1 1 RecQ mediated genome instability protein BRCA-2_OB1 PF09103.10 AIN99047.1 - 0.041 13.8 0.0 0.071 13.1 0.0 1.4 1 0 0 1 1 1 0 BRCA2, oligonucleotide/oligosaccharide-binding, domain 1 Steroid_dh PF02544.16 AIN99048.1 - 4.7e-25 88.3 3.7 7.9e-25 87.6 3.7 1.4 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase DUF1295 PF06966.12 AIN99048.1 - 2.3e-06 27.3 0.7 3.7e-06 26.6 0.7 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) YukD PF08817.10 AIN99048.1 - 0.019 15.7 0.1 0.044 14.5 0.1 1.6 1 1 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukD PEMT PF04191.13 AIN99048.1 - 0.2 12.1 5.5 0.17 12.3 0.7 2.4 1 1 1 2 2 2 0 Phospholipid methyltransferase ubiquitin PF00240.23 AIN99048.1 - 0.22 11.3 0.1 1 9.1 0.0 1.9 2 0 0 2 2 2 0 Ubiquitin family Dala_Dala_lig_C PF07478.13 AIN99049.1 - 8.6e-14 51.5 0.0 1.6e-13 50.7 0.0 1.4 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus SET PF00856.28 AIN99049.1 - 3.2e-07 30.9 1.0 2.9e-06 27.8 0.0 2.8 3 1 0 3 3 3 1 SET domain ATP-grasp_3 PF02655.14 AIN99049.1 - 0.00028 21.0 0.0 0.0019 18.3 0.0 2.2 1 1 0 1 1 1 1 ATP-grasp domain ATP-grasp PF02222.22 AIN99049.1 - 0.0025 17.4 0.0 0.0046 16.5 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain RimK PF08443.11 AIN99049.1 - 0.0031 17.1 0.0 0.0058 16.2 0.0 1.4 1 0 0 1 1 1 1 RimK-like ATP-grasp domain ATP-grasp_4 PF13535.6 AIN99049.1 - 0.012 15.2 0.0 0.022 14.3 0.0 1.4 1 0 0 1 1 1 0 ATP-grasp domain GARS_A PF01071.19 AIN99049.1 - 0.12 12.1 0.0 0.24 11.2 0.0 1.5 1 0 0 1 1 1 0 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain CHAP PF05257.16 AIN99050.1 - 4.2e-05 24.0 0.0 8.4e-05 23.1 0.0 1.5 1 0 0 1 1 1 1 CHAP domain zinc_ribbon_16 PF17034.5 AIN99051.1 - 3.7e-05 23.9 12.5 0.039 14.2 6.1 2.6 2 0 0 2 2 2 2 Zinc-ribbon like family Zn_ribbon_17 PF17120.5 AIN99051.1 - 0.53 10.0 22.1 0.02 14.5 13.9 2.7 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type Thioredoxin PF00085.20 AIN99052.1 - 0.013 15.5 0.0 0.023 14.7 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin DUF4542 PF15075.6 AIN99053.1 - 0.16 12.4 5.9 0.98 9.8 4.4 2.9 2 1 0 2 2 2 0 Domain of unknown function (DUF4542) bZIP_C PF12498.8 AIN99053.1 - 4.6 8.2 7.0 21 6.1 0.1 3.3 3 0 0 3 3 3 0 Basic leucine-zipper C terminal SLBP_RNA_bind PF15247.6 AIN99054.1 - 6.1e-23 80.7 3.9 1.8e-22 79.2 3.9 1.9 1 0 0 1 1 1 1 Histone RNA hairpin-binding protein RNA-binding domain Not3 PF04065.15 AIN99055.1 - 1e-61 208.3 24.4 1e-61 208.3 24.4 2.0 2 0 0 2 2 2 1 Not1 N-terminal domain, CCR4-Not complex component NOT2_3_5 PF04153.18 AIN99055.1 - 5.4e-34 117.1 9.5 5.4e-34 117.1 9.5 2.5 2 0 0 2 2 2 1 NOT2 / NOT3 / NOT5 family Syntaxin_2 PF14523.6 AIN99055.1 - 0.00037 20.8 0.8 0.00037 20.8 0.8 3.0 2 1 0 2 2 2 1 Syntaxin-like protein WD40 PF00400.32 AIN99056.1 - 3.2e-20 72.1 6.4 0.0012 19.6 0.0 6.5 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 AIN99056.1 - 2.4e-09 37.3 0.0 0.06 13.7 0.0 4.2 2 1 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain TPM_phosphatase PF04536.14 AIN99057.1 - 9.6e-17 61.3 0.0 1.3e-16 60.9 0.0 1.2 1 0 0 1 1 1 1 TPM domain zf-IS66 PF13005.7 AIN99057.1 - 0.28 11.6 0.0 0.28 11.6 0.0 3.2 4 0 0 4 4 4 0 zinc-finger binding domain of transposase IS66 DUF5539 PF17693.1 AIN99058.1 - 0.015 15.0 1.0 0.015 15.0 1.0 1.7 2 0 0 2 2 2 0 Family of unknown function (DUF5539) Erythro-docking PF09277.11 AIN99058.1 - 0.11 12.4 0.6 6.8 6.7 0.0 3.5 3 0 0 3 3 3 0 Erythronolide synthase, docking DUF883 PF05957.13 AIN99058.1 - 0.29 11.8 4.3 1.8 9.2 0.1 3.4 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF883) Vps55 PF04133.14 AIN99059.1 - 2.6e-28 98.4 3.1 3e-28 98.1 3.1 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting 55 ABC2_membrane PF01061.24 AIN99059.1 - 2.2 7.7 7.9 2.3 7.6 1.4 2.1 2 0 0 2 2 2 0 ABC-2 type transporter Phage_holin_3_6 PF07332.11 AIN99059.1 - 9.5 6.3 10.9 6.8 6.8 0.2 2.3 2 0 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III PAC3 PF10178.9 AIN99060.1 - 0.0005 20.2 0.0 0.00082 19.5 0.0 1.3 1 0 0 1 1 1 1 Proteasome assembly chaperone 3 DUF1499 PF07386.11 AIN99060.1 - 0.063 13.8 0.0 0.1 13.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1499) DFP PF04127.15 AIN99061.1 - 2.2e-20 73.3 0.0 1.5e-10 41.2 0.0 2.3 1 1 1 2 2 2 2 DNA / pantothenate metabolism flavoprotein DNA_repr_REX1B PF14966.6 AIN99062.1 - 0.00042 20.9 1.4 0.088 13.5 0.3 2.7 2 0 0 2 2 2 2 DNA repair REX1-B Cep57_MT_bd PF06657.13 AIN99062.1 - 0.15 12.6 1.5 0.25 11.8 0.1 2.1 3 0 0 3 3 3 0 Centrosome microtubule-binding domain of Cep57 TPR_12 PF13424.6 AIN99063.1 - 5.1e-10 39.5 31.5 4.2e-05 23.8 3.4 4.0 2 1 0 3 3 3 3 Tetratricopeptide repeat TPR_MalT PF17874.1 AIN99063.1 - 3.3e-05 23.4 25.6 0.017 14.5 1.5 2.9 1 1 1 3 3 3 3 MalT-like TPR region SNAP PF14938.6 AIN99063.1 - 0.0019 17.7 3.5 0.0019 17.7 3.5 3.1 1 1 2 3 3 3 1 Soluble NSF attachment protein, SNAP TPR_7 PF13176.6 AIN99063.1 - 0.0035 17.3 15.6 0.0042 17.0 0.5 5.8 5 1 1 6 6 6 1 Tetratricopeptide repeat TPR_2 PF07719.17 AIN99063.1 - 0.028 14.5 25.2 0.96 9.7 0.2 6.8 6 1 0 6 6 6 0 Tetratricopeptide repeat ANAPC5 PF12862.7 AIN99063.1 - 0.06 13.4 11.4 1.9 8.6 2.1 3.6 2 2 0 2 2 2 0 Anaphase-promoting complex subunit 5 TPR_16 PF13432.6 AIN99063.1 - 0.062 14.0 29.2 0.053 14.2 5.8 3.9 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.6 AIN99063.1 - 0.34 11.8 29.6 1.7 9.6 0.2 7.0 5 1 2 7 7 7 0 Tetratricopeptide repeat TPR_1 PF00515.28 AIN99063.1 - 1 9.3 15.6 0.69 9.8 0.1 5.3 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_8 PF13181.6 AIN99063.1 - 2.5 8.6 11.6 21 5.7 0.1 5.2 5 0 0 5 5 5 0 Tetratricopeptide repeat KinB_sensor PF16767.5 AIN99063.1 - 4.3 7.8 6.1 17 5.9 0.4 2.8 2 0 0 2 2 2 0 Sensor domain of alginate biosynthesis sensor protein KinB RRM_1 PF00076.22 AIN99064.1 - 0.11 12.3 0.0 0.19 11.6 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Kinesin PF00225.23 AIN99066.1 - 2.7e-77 259.9 0.1 2.7e-77 259.9 0.1 2.0 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 AIN99066.1 - 2.7e-21 76.1 0.0 7.4e-21 74.6 0.0 1.7 1 0 0 1 1 1 1 Microtubule binding HET PF06985.11 AIN99066.1 - 0.095 13.1 0.2 0.29 11.5 0.2 1.8 1 0 0 1 1 1 0 Heterokaryon incompatibility protein (HET) DUF1722 PF08349.11 AIN99066.1 - 0.13 12.6 2.6 0.31 11.3 1.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1722) FapA PF03961.13 AIN99066.1 - 0.22 10.1 8.7 0.013 14.1 3.7 1.4 2 0 0 2 2 2 0 Flagellar Assembly Protein A ResIII PF04851.15 AIN99066.1 - 0.23 11.5 0.9 0.61 10.1 0.1 2.1 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit DUF445 PF04286.12 AIN99066.1 - 0.96 9.2 5.4 1.9 8.2 3.6 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF445) AAA_16 PF13191.6 AIN99066.1 - 2.3 8.6 6.3 6.1 7.2 0.0 3.6 3 1 0 3 3 3 0 AAA ATPase domain UvrD-helicase PF00580.21 AIN99066.1 - 4.1 6.8 6.6 9.9 5.6 0.0 2.5 3 0 0 3 3 3 0 UvrD/REP helicase N-terminal domain AAA_22 PF13401.6 AIN99066.1 - 6.4 7.1 6.0 3.2 8.0 0.3 2.9 3 0 0 3 3 3 0 AAA domain Acylphosphatase PF00708.18 AIN99067.1 - 3.8e-23 81.7 0.0 5.7e-23 81.1 0.0 1.2 1 0 0 1 1 1 1 Acylphosphatase Kinesin PF00225.23 AIN99068.1 - 9e-101 337.1 0.0 1.9e-100 336.0 0.0 1.6 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 AIN99068.1 - 1.9e-26 92.8 0.0 2e-25 89.5 0.0 2.5 2 0 0 2 2 2 1 Microtubule binding HTH_Mga PF08280.11 AIN99068.1 - 0.073 13.1 0.2 0.2 11.7 0.2 1.6 1 0 0 1 1 1 0 M protein trans-acting positive regulator (MGA) HTH domain AAA_22 PF13401.6 AIN99068.1 - 0.077 13.3 9.2 0.3 11.4 0.0 4.0 3 0 0 3 3 3 0 AAA domain Pkinase PF00069.25 AIN99070.1 - 3.7e-57 193.7 0.0 2.2e-42 145.3 0.0 2.4 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 AIN99070.1 - 8.6e-33 113.7 0.0 4.2e-24 85.2 0.0 2.4 3 0 0 3 3 3 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 AIN99070.1 - 8.1e-05 21.6 0.0 0.00013 20.9 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 AIN99070.1 - 0.00032 20.1 0.0 0.048 13.0 0.0 2.3 2 0 0 2 2 2 2 Kinase-like APH PF01636.23 AIN99070.1 - 0.0071 16.3 0.0 0.014 15.3 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 AIN99070.1 - 0.011 15.1 0.0 0.017 14.4 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 AIN99070.1 - 0.012 15.2 0.0 0.021 14.4 0.0 1.3 1 0 0 1 1 1 0 RIO1 family Choline_kinase PF01633.20 AIN99070.1 - 0.12 12.0 0.0 0.2 11.2 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase HpcH_HpaI PF03328.14 AIN99072.1 - 4e-54 183.1 0.0 4.7e-54 182.8 0.0 1.0 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family rRNA_methylase PF06962.12 AIN99072.1 - 0.13 12.3 0.0 0.27 11.2 0.0 1.5 1 0 0 1 1 1 0 Putative rRNA methylase Zeta_toxin PF06414.12 AIN99073.1 - 0.00037 19.8 0.0 0.17 11.1 0.0 2.3 2 0 0 2 2 2 2 Zeta toxin Rad17 PF03215.15 AIN99073.1 - 0.0015 18.5 0.1 0.0026 17.7 0.1 1.3 1 0 0 1 1 1 1 Rad17 P-loop domain Cytidylate_kin PF02224.18 AIN99073.1 - 0.0033 17.2 0.2 0.025 14.3 0.0 2.2 2 0 0 2 2 2 1 Cytidylate kinase AAA_16 PF13191.6 AIN99073.1 - 0.011 16.1 0.0 0.028 14.8 0.0 1.8 1 1 0 1 1 1 0 AAA ATPase domain SRP54 PF00448.22 AIN99073.1 - 0.019 14.6 0.6 0.1 12.2 0.5 2.1 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain Ribosomal_S7 PF00177.21 AIN99073.1 - 0.026 14.2 0.0 0.11 12.2 0.0 1.9 2 0 0 2 2 2 0 Ribosomal protein S7p/S5e AAA_30 PF13604.6 AIN99073.1 - 0.037 13.7 0.3 0.11 12.2 0.1 1.8 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.6 AIN99073.1 - 0.041 14.3 0.0 0.12 12.8 0.0 1.8 2 0 0 2 2 2 0 AAA domain Ploopntkinase2 PF18747.1 AIN99073.1 - 0.051 12.8 0.0 0.12 11.6 0.0 1.6 2 0 0 2 2 2 0 P-loop Nucleotide Kinase2 AAA_22 PF13401.6 AIN99073.1 - 0.072 13.4 0.0 0.18 12.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain PIF1 PF05970.14 AIN99073.1 - 0.085 12.0 0.0 0.14 11.3 0.0 1.2 1 0 0 1 1 1 0 PIF1-like helicase AAA_18 PF13238.6 AIN99073.1 - 0.11 13.1 0.0 0.22 12.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain HHH_6 PF14579.6 AIN99073.1 - 0.12 12.7 0.0 0.49 10.7 0.0 2.0 1 1 0 1 1 1 0 Helix-hairpin-helix motif PEPCK_ATP PF01293.20 AIN99073.1 - 0.14 10.8 0.0 0.19 10.3 0.0 1.2 1 0 0 1 1 1 0 Phosphoenolpyruvate carboxykinase AAA_33 PF13671.6 AIN99073.1 - 0.15 12.2 0.1 0.27 11.4 0.1 1.6 1 1 0 1 1 1 0 AAA domain NIF PF03031.18 AIN99074.1 - 6.5e-49 165.7 0.1 9.9e-49 165.1 0.1 1.3 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase G-alpha PF00503.20 AIN99074.1 - 0.054 12.6 0.0 0.079 12.1 0.0 1.2 1 0 0 1 1 1 0 G-protein alpha subunit DUF2777 PF10949.8 AIN99074.1 - 0.092 12.4 0.1 0.14 11.8 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2777) RST PF12174.8 AIN99074.1 - 0.19 11.7 2.4 0.19 11.7 0.1 2.1 2 0 0 2 2 2 0 RCD1-SRO-TAF4 (RST) plant domain SNF2_N PF00176.23 AIN99076.1 - 1.2e-40 139.3 0.2 2e-40 138.6 0.2 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 AIN99076.1 - 3.6e-17 62.7 0.0 7e-17 61.8 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain PHD PF00628.29 AIN99076.1 - 2.1e-07 30.7 14.9 0.00069 19.5 4.8 2.6 2 0 0 2 2 2 2 PHD-finger ResIII PF04851.15 AIN99076.1 - 8.7e-07 29.1 0.0 1.4e-06 28.4 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit C1_1 PF00130.22 AIN99076.1 - 0.0058 16.5 3.7 0.0058 16.5 3.7 2.6 2 0 0 2 2 2 1 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-PHD-like PF15446.6 AIN99076.1 - 0.0086 15.7 9.3 0.03 14.0 1.7 2.5 2 0 0 2 2 2 2 PHD/FYVE-zinc-finger like domain SWI2_SNF2 PF18766.1 AIN99076.1 - 0.014 15.1 0.0 0.025 14.2 0.0 1.3 1 0 0 1 1 1 0 SWI2/SNF2 ATPase DUF282 PF03380.14 AIN99076.1 - 0.05 13.5 0.3 0.11 12.4 0.3 1.6 1 0 0 1 1 1 0 Caenorhabditis protein of unknown function, DUF282 HDA2-3 PF11496.8 AIN99076.1 - 0.13 11.4 0.0 0.33 10.1 0.0 1.5 1 1 0 1 1 1 0 Class II histone deacetylase complex subunits 2 and 3 Prok-RING_1 PF14446.6 AIN99076.1 - 2.6 8.0 20.5 1.2 9.1 7.3 2.6 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 SpoIIE PF07228.12 AIN99077.1 - 1.7e-15 57.4 0.0 7e-14 52.2 0.0 2.1 2 0 0 2 2 2 1 Stage II sporulation protein E (SpoIIE) PP2C_2 PF13672.6 AIN99077.1 - 4.2e-05 23.3 0.3 0.0001 22.1 0.3 1.5 1 1 0 1 1 1 1 Protein phosphatase 2C PP2C PF00481.21 AIN99077.1 - 0.00045 19.9 0.1 0.005 16.5 0.0 2.1 2 0 0 2 2 2 1 Protein phosphatase 2C Rieske PF00355.26 AIN99078.1 - 5e-07 29.6 0.3 1e-06 28.6 0.3 1.5 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Rieske_2 PF13806.6 AIN99078.1 - 5.1e-06 26.4 0.0 8.9e-06 25.6 0.0 1.4 1 0 0 1 1 1 1 Rieske-like [2Fe-2S] domain GTP_EFTU PF00009.27 AIN99079.1 - 3.9e-50 170.1 0.0 6.3e-50 169.4 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.24 AIN99079.1 - 2.3e-15 56.4 0.0 5e-15 55.3 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 AIN99079.1 - 4.2e-06 27.0 0.0 9.8e-06 25.9 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_IV PF03764.18 AIN99079.1 - 3.8e-05 23.5 0.0 9.4e-05 22.2 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_II PF14492.6 AIN99079.1 - 0.00058 19.9 0.1 0.0024 17.9 0.0 2.0 2 0 0 2 2 2 1 Elongation Factor G, domain II Poly_export PF02563.16 AIN99079.1 - 0.16 12.2 0.0 4.7 7.5 0.0 2.7 2 0 0 2 2 2 0 Polysaccharide biosynthesis/export protein cobW PF02492.19 AIN99079.1 - 0.17 11.4 0.0 0.36 10.4 0.0 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain mRNA_triPase PF02940.15 AIN99081.1 - 3.4e-13 49.8 0.0 7.6e-12 45.4 0.0 2.4 1 1 0 1 1 1 1 mRNA capping enzyme, beta chain HCV_NS5a_1b PF08301.13 AIN99081.1 - 0.00051 20.6 0.8 0.0075 16.8 0.0 2.7 3 0 0 3 3 3 1 Hepatitis C virus non-structural 5a domain 1b PRTP PF01366.18 AIN99081.1 - 0.034 12.2 0.0 0.041 11.9 0.0 1.1 1 0 0 1 1 1 0 Herpesvirus processing and transport protein TPR_2 PF07719.17 AIN99082.1 - 1.2e-19 68.7 29.2 0.0058 16.6 0.0 7.3 6 1 1 7 7 7 6 Tetratricopeptide repeat TPR_1 PF00515.28 AIN99082.1 - 1.2e-15 56.6 24.8 0.00013 21.6 0.1 6.9 6 1 1 7 7 7 5 Tetratricopeptide repeat TPR_8 PF13181.6 AIN99082.1 - 2.2e-08 33.6 25.2 0.078 13.2 0.1 6.8 6 1 1 7 7 7 3 Tetratricopeptide repeat TPR_12 PF13424.6 AIN99082.1 - 5.7e-08 32.9 17.1 0.0022 18.2 2.2 4.7 3 3 1 4 4 4 3 Tetratricopeptide repeat TPR_14 PF13428.6 AIN99082.1 - 2.1e-05 25.0 18.3 0.57 11.1 0.0 6.6 4 2 3 7 7 6 1 Tetratricopeptide repeat TPR_19 PF14559.6 AIN99082.1 - 8.4e-05 23.0 13.6 0.48 11.0 0.1 4.7 2 2 1 4 4 4 1 Tetratricopeptide repeat TPR_11 PF13414.6 AIN99082.1 - 8.5e-05 22.2 23.8 0.94 9.2 0.6 7.3 5 2 1 6 6 6 3 TPR repeat zf-C2H2_10 PF16588.5 AIN99082.1 - 0.0001 21.9 3.5 0.00026 20.6 3.5 1.7 1 0 0 1 1 1 1 C2H2 zinc-finger Fis1_TPR_C PF14853.6 AIN99082.1 - 0.0001 22.3 4.1 0.071 13.2 0.0 3.5 3 0 0 3 3 3 2 Fis1 C-terminal tetratricopeptide repeat TPR_16 PF13432.6 AIN99082.1 - 0.00017 22.2 21.4 0.21 12.3 0.1 4.8 2 2 3 5 5 5 3 Tetratricopeptide repeat TPR_17 PF13431.6 AIN99082.1 - 0.0034 17.6 8.4 1.3 9.6 0.1 5.5 6 0 0 6 6 6 1 Tetratricopeptide repeat NYD-SP12_N PF15015.6 AIN99082.1 - 0.0047 15.3 0.8 0.017 13.6 0.3 1.9 2 0 0 2 2 2 1 Spermatogenesis-associated, N-terminal zf-CCHC PF00098.23 AIN99082.1 - 0.017 15.1 1.3 0.035 14.2 1.3 1.5 1 0 0 1 1 1 0 Zinc knuckle MIT PF04212.18 AIN99082.1 - 0.035 14.2 13.2 1.2 9.3 0.3 4.4 3 2 0 3 3 3 0 MIT (microtubule interacting and transport) domain TPR_6 PF13174.6 AIN99082.1 - 0.82 10.4 11.9 16 6.4 0.1 5.8 6 1 0 6 6 5 0 Tetratricopeptide repeat KBP_C PF12309.8 AIN99083.1 - 1.2e-46 160.0 2.2 9.2e-46 157.0 1.2 2.4 2 1 0 2 2 2 1 KIF-1 binding protein C terminal eIF3_subunit PF08597.10 AIN99084.1 - 4.1e-06 26.9 15.6 6.7e-06 26.2 15.6 1.3 1 1 0 1 1 1 1 Translation initiation factor eIF3 subunit DUF4695 PF15766.5 AIN99084.1 - 0.27 11.5 4.4 1.9 8.8 0.6 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4695) Pinin_SDK_memA PF04696.13 AIN99084.1 - 1.1 9.4 8.5 4.3 7.4 3.6 2.2 2 0 0 2 2 2 0 pinin/SDK/memA/ protein conserved region CoA_binding PF02629.19 AIN99085.1 - 2.9e-26 92.0 3.7 3.8e-26 91.6 2.3 1.9 2 0 0 2 2 2 1 CoA binding domain Ligase_CoA PF00549.19 AIN99085.1 - 2.6e-22 79.3 1.5 2.7e-22 79.2 0.1 1.7 2 0 0 2 2 2 1 CoA-ligase Succ_CoA_lig PF13607.6 AIN99085.1 - 9.1e-08 32.0 0.0 1.8e-07 31.0 0.0 1.5 1 0 0 1 1 1 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.6 AIN99085.1 - 0.00017 22.1 0.1 0.00032 21.2 0.1 1.5 1 0 0 1 1 1 1 CoA binding domain BRO1 PF03097.18 AIN99086.1 - 4.6e-23 81.7 0.2 5.9e-23 81.3 0.2 1.1 1 0 0 1 1 1 1 BRO1-like domain UPF0449 PF15136.6 AIN99087.1 - 0.033 14.7 1.0 0.062 13.8 1.0 1.4 1 0 0 1 1 1 0 Uncharacterised protein family UPF0449 Rad60-SLD PF11976.8 AIN99088.1 - 7e-06 25.8 0.3 1.2e-05 25.1 0.3 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 AIN99088.1 - 7.2e-06 25.7 0.0 1.2e-05 24.9 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family Ub-RnfH PF03658.14 AIN99088.1 - 0.11 12.8 0.0 0.23 11.9 0.0 1.5 1 0 0 1 1 1 0 RnfH family Ubiquitin Ubiquitin_4 PF18036.1 AIN99088.1 - 0.26 11.4 0.9 11 6.1 0.0 2.3 1 1 1 2 2 2 0 Ubiquitin-like domain CLP1_P PF16575.5 AIN99089.1 - 1.8e-15 57.3 0.0 3.1e-15 56.4 0.0 1.5 1 0 0 1 1 1 1 mRNA cleavage and polyadenylation factor CLP1 P-loop CLP1_N PF16573.5 AIN99089.1 - 3e-07 30.6 0.0 4.7e-07 29.9 0.0 1.3 1 0 0 1 1 1 1 N-terminal beta-sandwich domain of polyadenylation factor Sec1 PF00995.23 AIN99090.1 - 7.2e-90 302.9 0.0 8.8e-90 302.6 0.0 1.0 1 0 0 1 1 1 1 Sec1 family ATP-synt_F PF01990.17 AIN99090.1 - 0.01 16.1 0.8 1.6 9.1 0.0 3.6 3 1 0 3 3 3 0 ATP synthase (F/14-kDa) subunit DUF2730 PF10805.8 AIN99090.1 - 0.1 12.7 0.1 0.25 11.5 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2730) DnaJ PF00226.31 AIN99091.1 - 7.8e-23 80.4 5.1 1.8e-22 79.2 5.1 1.7 1 0 0 1 1 1 1 DnaJ domain zf-C2H2_jaz PF12171.8 AIN99091.1 - 4e-10 39.7 6.3 8e-10 38.7 6.3 1.6 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 AIN99091.1 - 4.9e-08 33.1 3.0 9e-08 32.3 3.0 1.4 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.7 AIN99091.1 - 4.2e-05 23.8 0.2 0.0002 21.7 0.1 2.1 2 0 0 2 2 2 1 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.6 AIN99091.1 - 0.011 16.5 0.9 0.034 15.0 0.4 2.1 2 0 0 2 2 1 0 C2H2-type zinc finger AKAP95 PF04988.12 AIN99091.1 - 0.012 15.9 0.2 0.03 14.6 0.2 1.7 1 0 0 1 1 1 0 A-kinase anchoring protein 95 (AKAP95) zf-C2H2 PF00096.26 AIN99091.1 - 0.012 16.0 1.4 0.025 15.0 1.4 1.6 1 0 0 1 1 1 0 Zinc finger, C2H2 type ABATE PF07336.11 AIN99091.1 - 0.18 12.5 4.8 0.38 11.4 4.8 1.5 1 0 0 1 1 1 0 Putative stress-induced transcription regulator HNH_5 PF14279.6 AIN99091.1 - 0.2 11.5 0.6 0.39 10.6 0.6 1.4 1 0 0 1 1 1 0 HNH endonuclease DUF4136 PF13590.6 AIN99091.1 - 0.24 12.0 4.5 0.71 10.5 4.5 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4136) zf-H2C2_2 PF13465.6 AIN99091.1 - 3.1 8.4 5.0 0.45 11.0 0.6 1.9 2 0 0 2 2 2 0 Zinc-finger double domain ParcG PF10274.9 AIN99092.1 - 1.4e-78 263.2 0.0 1.9e-78 262.8 0.0 1.2 1 0 0 1 1 1 1 Parkin co-regulated protein PCI PF01399.27 AIN99093.1 - 8e-07 29.5 0.1 2.4e-06 28.0 0.0 1.8 2 0 0 2 2 2 1 PCI domain TPR_2 PF07719.17 AIN99093.1 - 0.43 10.8 5.0 5.7 7.3 0.2 4.3 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_12 PF13424.6 AIN99093.1 - 2.9 8.3 7.1 14 6.1 0.1 3.5 3 1 0 3 3 3 0 Tetratricopeptide repeat PhaP_Bmeg PF09602.10 AIN99094.1 - 0.054 13.4 4.6 1.7 8.5 1.3 2.5 1 1 1 2 2 2 0 Polyhydroxyalkanoic acid inclusion protein (PhaP_Bmeg) Gp-FAR-1 PF05823.12 AIN99094.1 - 0.066 13.6 0.1 0.14 12.5 0.1 1.5 1 0 0 1 1 1 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) DUF4004 PF13171.6 AIN99094.1 - 0.081 13.2 1.4 0.24 11.6 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4004) DUF3135 PF11333.8 AIN99094.1 - 0.092 13.0 5.3 24 5.2 0.1 4.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3135) Fib_alpha PF08702.10 AIN99094.1 - 0.11 12.7 5.1 0.11 12.7 1.0 2.4 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family SOAR PF16533.5 AIN99094.1 - 0.18 11.8 6.8 2 8.4 0.9 2.9 2 0 0 2 2 2 0 STIM1 Orai1-activating region Phage_holin_7_1 PF16081.5 AIN99094.1 - 0.21 11.8 0.1 0.21 11.8 0.1 2.8 1 1 2 3 3 3 0 Mycobacterial 2 TMS Phage Holin (M2 Hol) Family DUF913 PF06025.12 AIN99094.1 - 0.22 10.4 1.7 2.6 6.9 0.0 2.5 2 0 0 2 2 2 0 Domain of Unknown Function (DUF913) CSN5_C PF18323.1 AIN99094.1 - 0.38 11.7 3.5 1.9 9.4 0.4 2.7 1 1 1 2 2 2 0 Cop9 signalosome subunit 5 C-terminal domain Cytochrom_B562 PF07361.11 AIN99094.1 - 1 10.0 4.2 7.3 7.3 4.2 2.5 1 1 0 1 1 1 0 Cytochrome b562 RecC_C PF17946.1 AIN99094.1 - 6.9 6.4 10.7 8.8 6.0 7.9 2.6 3 1 0 3 3 3 0 RecC C-terminal domain Pex2_Pex12 PF04757.14 AIN99095.1 - 1.1e-28 100.4 13.6 1.4e-28 100.1 13.6 1.1 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4_4 PF15227.6 AIN99095.1 - 0.011 15.9 8.9 0.021 15.0 8.9 1.5 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.25 AIN99095.1 - 0.024 14.5 13.0 0.038 13.9 13.0 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) TFIIS_C PF01096.18 AIN99095.1 - 0.18 11.7 6.0 0.47 10.3 6.0 1.7 1 0 0 1 1 1 0 Transcription factor S-II (TFIIS) zf-C3HC4_3 PF13920.6 AIN99095.1 - 0.21 11.5 13.9 0.3 11.0 13.9 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) TF_Zn_Ribbon PF08271.12 AIN99095.1 - 0.27 10.8 6.0 0.11 12.0 2.2 2.1 2 0 0 2 2 2 0 TFIIB zinc-binding zf-RING_5 PF14634.6 AIN99095.1 - 0.62 10.1 12.9 1 9.4 12.9 1.3 1 0 0 1 1 1 0 zinc-RING finger domain zf-RING_UBOX PF13445.6 AIN99095.1 - 0.97 9.5 9.8 1.8 8.6 9.8 1.5 1 0 0 1 1 1 0 RING-type zinc-finger zf-RING_2 PF13639.6 AIN99095.1 - 1.3 9.4 11.2 2.2 8.7 11.2 1.4 1 0 0 1 1 1 0 Ring finger domain zf-C3HC4_2 PF13923.6 AIN99095.1 - 2.9 7.8 9.4 8.1 6.4 9.5 1.8 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) PHD PF00628.29 AIN99096.1 - 4.8e-06 26.4 14.9 8.3e-06 25.6 7.9 2.5 2 0 0 2 2 2 2 PHD-finger zf-PHD-like PF15446.6 AIN99096.1 - 0.0032 17.1 4.8 0.012 15.2 1.2 2.1 2 0 0 2 2 2 1 PHD/FYVE-zinc-finger like domain SCAB-Ig PF16709.5 AIN99096.1 - 0.078 13.0 0.0 0.13 12.3 0.0 1.4 1 0 0 1 1 1 0 Ig domain of plant-specific actin-binding protein DUF1719 PF08224.11 AIN99096.1 - 0.087 11.9 0.6 0.15 11.1 0.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1719) zf-C4_ClpX PF06689.13 AIN99096.1 - 0.36 10.8 3.4 1.9 8.5 3.4 2.1 1 1 0 1 1 1 0 ClpX C4-type zinc finger PHD_4 PF16866.5 AIN99096.1 - 2.7 8.2 10.1 22 5.2 10.2 2.2 1 1 0 1 1 1 0 PHD-finger UbiA PF01040.18 AIN99098.1 - 0.067 12.5 0.1 0.084 12.2 0.1 1.1 1 0 0 1 1 1 0 UbiA prenyltransferase family DHHC PF01529.20 AIN99101.1 - 5.8e-35 120.3 4.3 5.8e-35 120.3 4.3 2.2 2 0 0 2 2 2 1 DHHC palmitoyltransferase LPG_synthase_TM PF03706.13 AIN99101.1 - 0.81 9.2 10.6 0.4 10.2 1.3 2.1 2 0 0 2 2 2 0 Lysylphosphatidylglycerol synthase TM region Pex2_Pex12 PF04757.14 AIN99102.1 - 9.5e-13 48.3 0.2 2.3e-05 24.1 0.0 2.1 1 1 1 2 2 2 2 Pex2 / Pex12 amino terminal region zf-C3HC4_3 PF13920.6 AIN99102.1 - 3.1e-09 36.5 10.8 4.6e-09 36.0 10.8 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 AIN99102.1 - 9.8e-09 35.4 13.0 1.6e-08 34.8 13.0 1.3 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 AIN99102.1 - 8.2e-08 32.1 10.7 1.4e-07 31.3 10.7 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.25 AIN99102.1 - 3.1e-06 26.9 12.0 5e-06 26.3 12.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 AIN99102.1 - 3.8e-06 27.1 7.2 6.7e-06 26.3 7.2 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger domain Prok-RING_4 PF14447.6 AIN99102.1 - 4e-06 26.6 10.8 6.4e-06 25.9 10.8 1.3 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-ANAPC11 PF12861.7 AIN99102.1 - 1.4e-05 25.0 5.3 2.5e-05 24.3 5.3 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_4 PF15227.6 AIN99102.1 - 4.3e-05 23.6 11.5 7.8e-05 22.7 11.5 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.6 AIN99102.1 - 0.00049 20.1 8.5 0.0015 18.5 8.1 1.9 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 AIN99102.1 - 0.00052 19.8 11.8 0.0009 19.0 11.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) TRAM_LAG1_CLN8 PF03798.16 AIN99102.1 - 0.031 14.0 0.2 0.054 13.2 0.2 1.4 1 0 0 1 1 1 0 TLC domain DUF4381 PF14316.6 AIN99102.1 - 0.087 13.1 0.0 0.23 11.7 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) U-box PF04564.15 AIN99102.1 - 0.13 12.4 0.0 0.3 11.3 0.0 1.5 1 0 0 1 1 1 0 U-box domain zf-Di19 PF05605.12 AIN99102.1 - 0.24 11.7 2.7 0.38 11.1 0.2 2.2 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding Zn_ribbon_17 PF17120.5 AIN99102.1 - 0.66 9.6 8.8 1.4 8.6 8.8 1.6 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-RING_6 PF14835.6 AIN99102.1 - 0.97 9.4 5.5 2.8 7.9 5.0 1.9 2 0 0 2 2 2 0 zf-RING of BARD1-type protein zf-Nse PF11789.8 AIN99102.1 - 1.4 8.8 4.6 3 7.7 4.6 1.6 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-RING_4 PF14570.6 AIN99102.1 - 5.2 6.9 11.5 17 5.3 11.6 1.8 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain IBR PF01485.21 AIN99102.1 - 6.5 7.1 10.8 4.3 7.6 8.5 1.9 1 1 1 2 2 2 0 IBR domain, a half RING-finger domain LRR_4 PF12799.7 AIN99103.1 - 4.9e-09 36.3 0.9 0.0021 18.4 0.3 2.8 2 0 0 2 2 2 2 Leucine Rich repeats (2 copies) EF-hand_7 PF13499.6 AIN99103.1 - 2.3e-06 27.9 0.0 1.1e-05 25.8 0.0 2.1 1 0 0 1 1 1 1 EF-hand domain pair LRR_8 PF13855.6 AIN99103.1 - 4.7e-06 26.3 2.1 4.7e-06 26.3 2.1 2.1 2 0 0 2 2 2 1 Leucine rich repeat LRR_6 PF13516.6 AIN99103.1 - 3.1e-05 23.7 0.5 0.35 11.1 0.2 3.1 2 0 0 2 2 2 2 Leucine Rich repeat EF-hand_1 PF00036.32 AIN99103.1 - 0.00092 18.6 0.1 0.013 15.0 0.0 2.9 3 0 0 3 3 3 1 EF hand EF-hand_6 PF13405.6 AIN99103.1 - 0.0022 17.8 0.1 0.022 14.7 0.0 2.7 2 0 0 2 2 2 1 EF-hand domain EF-hand_8 PF13833.6 AIN99103.1 - 0.009 15.8 0.1 0.25 11.2 0.0 2.7 1 1 1 2 2 2 1 EF-hand domain pair LRR_1 PF00560.33 AIN99103.1 - 0.011 16.1 2.8 0.73 10.6 0.1 3.0 2 0 0 2 2 2 0 Leucine Rich Repeat REV1_C PF16727.5 AIN99103.1 - 0.018 15.4 1.4 0.14 12.6 0.2 2.5 2 0 0 2 2 2 0 DNA repair protein REV1 C-terminal domain DUF4352 PF11611.8 AIN99104.1 - 0.0048 17.2 0.1 0.0087 16.3 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4352) RNase_II_C_S1 PF18614.1 AIN99104.1 - 0.038 13.9 0.2 0.082 12.9 0.2 1.6 1 0 0 1 1 1 0 RNase II-type exonuclease C-terminal S1 domain SPC12 PF06645.13 AIN99105.1 - 5.5e-08 32.8 0.8 7.3e-08 32.4 0.8 1.2 1 0 0 1 1 1 1 Microsomal signal peptidase 12 kDa subunit (SPC12) FA_desaturase PF00487.24 AIN99105.1 - 0.064 13.1 0.9 0.077 12.8 0.9 1.2 1 0 0 1 1 1 0 Fatty acid desaturase VPS9 PF02204.18 AIN99106.1 - 5.1e-14 52.4 0.1 7.7e-14 51.8 0.1 1.3 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain MORN PF02493.20 AIN99106.1 - 5.9e-08 32.2 7.0 5e-06 26.1 0.5 3.9 3 0 0 3 3 3 3 MORN repeat Pkinase PF00069.25 AIN99107.1 - 2.1e-65 220.8 0.0 2.6e-65 220.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 AIN99107.1 - 2.1e-39 135.4 0.0 2.9e-39 134.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 AIN99107.1 - 4.7e-06 26.1 0.0 8.8e-06 25.2 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 AIN99107.1 - 0.0084 16.1 0.0 0.21 11.5 0.0 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 AIN99107.1 - 0.015 14.6 0.0 0.03 13.7 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family ADK PF00406.22 AIN99110.1 - 9.2e-37 126.5 0.0 1.1e-36 126.2 0.0 1.0 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 AIN99110.1 - 4.2e-19 69.3 0.0 6.5e-19 68.7 0.0 1.2 1 0 0 1 1 1 1 AAA domain ADK_lid PF05191.14 AIN99110.1 - 1.6e-11 44.0 3.0 2.6e-11 43.3 3.0 1.4 1 0 0 1 1 1 1 Adenylate kinase, active site lid AAA_18 PF13238.6 AIN99110.1 - 0.001 19.6 0.0 0.0015 19.0 0.0 1.3 1 0 0 1 1 1 1 AAA domain A2L_zn_ribbon PF08792.10 AIN99110.1 - 0.0015 18.2 0.9 0.35 10.6 0.0 2.4 2 0 0 2 2 2 2 A2L zinc ribbon domain AAA_33 PF13671.6 AIN99110.1 - 0.0037 17.4 0.0 0.0059 16.8 0.0 1.3 1 0 0 1 1 1 1 AAA domain NTPase_1 PF03266.15 AIN99110.1 - 0.099 12.6 0.0 0.19 11.6 0.0 1.5 1 0 0 1 1 1 0 NTPase zf-C2H2_3 PF13878.6 AIN99110.1 - 0.12 12.3 1.7 0.19 11.6 0.0 2.0 2 0 0 2 2 2 0 zinc-finger of acetyl-transferase ESCO Arv1 PF04161.13 AIN99112.1 - 5.1e-30 105.2 6.1 7.5e-30 104.7 6.1 1.3 1 0 0 1 1 1 1 Arv1-like family PH_12 PF16457.5 AIN99113.1 - 0.0045 17.5 3.9 0.01 16.4 0.0 3.6 3 1 0 3 3 3 1 Pleckstrin homology domain DUF2935 PF11155.8 AIN99113.1 - 1.2 9.4 9.3 1e+02 3.2 5.0 4.2 2 1 0 3 3 3 0 Domain of unknown function (DUF2935) Creatinase_N_2 PF16189.5 AIN99115.1 - 3.1e-39 134.7 0.0 7.6e-38 130.1 0.0 2.3 2 0 0 2 2 2 1 Creatinase/Prolidase N-terminal domain Creatinase_N PF01321.18 AIN99115.1 - 2.7e-18 66.9 0.1 3e-14 53.8 0.1 2.3 2 0 0 2 2 2 2 Creatinase/Prolidase N-terminal domain LSM PF01423.22 AIN99117.1 - 4e-13 48.9 0.0 5.2e-13 48.5 0.0 1.2 1 0 0 1 1 1 1 LSM domain DUF2642 PF10842.8 AIN99117.1 - 0.13 12.1 0.0 0.23 11.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2642) Brix PF04427.18 AIN99118.1 - 4.8e-28 98.6 0.0 6.3e-28 98.2 0.0 1.1 1 0 0 1 1 1 1 Brix domain Glyoxalase_4 PF13669.6 AIN99119.1 - 4.9e-18 65.4 0.0 5.9e-18 65.1 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_3 PF13468.6 AIN99119.1 - 0.021 14.9 0.0 0.025 14.7 0.0 1.1 1 0 0 1 1 1 0 Glyoxalase-like domain Glyoxalase PF00903.25 AIN99119.1 - 0.036 14.3 0.0 0.045 13.9 0.0 1.2 1 0 0 1 1 1 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily GDC-P PF02347.16 AIN99120.1 - 6.5e-170 565.6 0.0 2.5e-155 517.6 0.1 3.1 3 0 0 3 3 3 3 Glycine cleavage system P-protein Beta_elim_lyase PF01212.21 AIN99120.1 - 0.0011 18.3 0.0 0.0029 16.9 0.0 1.6 1 0 0 1 1 1 1 Beta-eliminating lyase Cys_Met_Meta_PP PF01053.20 AIN99120.1 - 0.0051 15.4 0.1 0.016 13.7 0.1 1.8 2 0 0 2 2 2 1 Cys/Met metabolism PLP-dependent enzyme DUF4473 PF14747.6 AIN99120.1 - 0.016 15.8 0.0 0.07 13.7 0.0 2.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4473) Pkinase PF00069.25 AIN99121.1 - 3.4e-57 193.8 0.0 3.8e-57 193.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 AIN99121.1 - 7.6e-23 81.1 0.0 8e-23 81.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 AIN99121.1 - 0.0029 17.0 0.0 0.011 15.0 0.0 1.7 2 0 0 2 2 2 1 Kinase-like FTA2 PF13095.6 AIN99121.1 - 0.043 13.4 0.0 0.063 12.9 0.0 1.2 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 ALMT PF11744.8 AIN99122.1 - 9.4 4.9 7.5 13 4.5 7.5 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter Rhomboid PF01694.22 AIN99127.1 - 4.8e-05 23.4 1.6 0.00011 22.2 1.6 1.6 1 1 0 1 1 1 1 Rhomboid family Pribosyltran PF00156.27 AIN99128.1 - 9.9e-19 67.4 0.0 1.3e-18 67.1 0.0 1.1 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.6 AIN99128.1 - 0.00041 19.9 0.0 0.00057 19.4 0.0 1.2 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase PRTase_2 PF15609.6 AIN99128.1 - 0.026 14.0 0.0 0.039 13.4 0.0 1.5 1 1 0 1 1 1 0 Phosphoribosyl transferase MCM_bind PF09739.9 AIN99129.1 - 4.8e-37 127.7 0.0 2.6e-36 125.3 0.0 1.8 1 1 0 1 1 1 1 Mini-chromosome maintenance replisome factor NIF PF03031.18 AIN99130.1 - 6.6e-50 168.9 0.2 1.1e-49 168.1 0.1 1.4 2 0 0 2 2 2 1 NLI interacting factor-like phosphatase zf_PR_Knuckle PF18445.1 AIN99130.1 - 0.038 13.8 0.0 0.084 12.7 0.0 1.5 1 0 0 1 1 1 0 PR zinc knuckle motif HAD PF12710.7 AIN99130.1 - 0.15 12.4 0.1 1 9.7 0.0 1.9 1 1 1 2 2 2 0 haloacid dehalogenase-like hydrolase Ribosomal_L30 PF00327.20 AIN99131.1 - 1.5e-18 66.4 2.2 1.5e-18 66.4 2.2 2.1 2 0 0 2 2 2 1 Ribosomal protein L30p/L7e Ribosomal_L30_N PF08079.12 AIN99131.1 - 2.2e-15 56.7 11.0 4.1e-15 55.8 11.0 1.5 1 0 0 1 1 1 1 Ribosomal L30 N-terminal domain DUF2062 PF09835.9 AIN99132.1 - 2.3e-06 27.6 4.2 2.5e-06 27.4 4.2 1.0 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2062) NifU PF01106.17 AIN99133.1 - 6.7e-27 93.4 0.0 1.8e-26 92.1 0.0 1.8 2 0 0 2 2 2 1 NifU-like domain Nfu_N PF08712.11 AIN99133.1 - 7.9e-22 77.1 0.0 1.4e-21 76.3 0.0 1.4 1 0 0 1 1 1 1 Scaffold protein Nfu/NifU N terminal eRF1_1 PF03463.15 AIN99134.1 - 4.8e-32 110.7 0.3 1e-31 109.6 0.1 1.7 2 0 0 2 2 2 1 eRF1 domain 1 eRF1_2 PF03464.15 AIN99134.1 - 2.1e-18 66.9 0.1 3.3e-18 66.3 0.1 1.3 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.15 AIN99134.1 - 4.2e-14 53.0 0.0 1.6e-13 51.1 0.0 2.0 2 1 0 2 2 2 1 eRF1 domain 3 DUF3145 PF11343.8 AIN99134.1 - 0.093 12.3 0.0 0.29 10.7 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3145) SIR2 PF02146.17 AIN99135.1 - 1.4e-56 191.2 0.0 2e-56 190.7 0.0 1.2 1 0 0 1 1 1 1 Sir2 family zinc_ribbon_4 PF13717.6 AIN99135.1 - 0.0014 18.5 1.9 0.0034 17.3 0.3 2.2 2 0 0 2 2 2 1 zinc-ribbon domain Paired_CXXCH_1 PF09699.10 AIN99135.1 - 0.03 14.1 0.5 0.06 13.1 0.5 1.5 1 0 0 1 1 1 0 Doubled CXXCH motif (Paired_CXXCH_1) LIDHydrolase PF10230.9 AIN99136.1 - 1e-61 208.8 0.0 1.2e-61 208.6 0.0 1.0 1 0 0 1 1 1 1 Lipid-droplet associated hydrolase Hydrolase_4 PF12146.8 AIN99136.1 - 2.2e-10 40.2 0.0 2.6e-10 40.0 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 AIN99136.1 - 3.8e-07 30.0 0.0 3.7e-06 26.8 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 AIN99136.1 - 2.5e-05 25.0 0.0 3.8e-05 24.4 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF1057 PF06342.12 AIN99136.1 - 0.0059 15.7 0.0 0.0078 15.3 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1057) Thioesterase PF00975.20 AIN99136.1 - 0.0069 16.5 0.0 0.012 15.7 0.0 1.3 1 0 0 1 1 1 1 Thioesterase domain Abhydrolase_5 PF12695.7 AIN99136.1 - 0.042 13.6 0.1 0.18 11.5 0.1 2.0 1 1 0 1 1 1 0 Alpha/beta hydrolase family PGAP1 PF07819.13 AIN99136.1 - 0.049 13.4 0.0 0.098 12.4 0.0 1.4 1 0 0 1 1 1 0 PGAP1-like protein Lipase_3 PF01764.25 AIN99136.1 - 0.14 12.1 0.0 0.27 11.1 0.0 1.5 1 0 0 1 1 1 0 Lipase (class 3) IF4E PF01652.18 AIN99138.1 - 8.5e-13 48.4 0.0 1e-12 48.1 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E MMR_HSR1 PF01926.23 AIN99141.1 - 1.9e-38 131.1 0.0 1.6e-19 70.1 0.0 2.4 2 0 0 2 2 2 2 50S ribosome-binding GTPase GTP_EFTU PF00009.27 AIN99141.1 - 2.8e-23 82.5 0.8 4.8e-11 42.5 0.0 3.6 2 1 1 3 3 3 3 Elongation factor Tu GTP binding domain FeoB_N PF02421.18 AIN99141.1 - 8.3e-16 57.9 0.1 1.9e-07 30.7 0.0 2.4 2 0 0 2 2 2 2 Ferrous iron transport protein B Dynamin_N PF00350.23 AIN99141.1 - 1.3e-15 57.9 0.1 0.0013 18.9 0.0 4.4 3 1 1 4 4 4 4 Dynamin family KH_dom-like PF14714.6 AIN99141.1 - 5e-13 49.2 0.4 1.1e-12 48.1 0.4 1.6 1 0 0 1 1 1 1 KH-domain-like of EngA bacterial GTPase enzymes, C-terminal RsgA_GTPase PF03193.16 AIN99141.1 - 1.2e-11 44.8 0.2 0.01 15.7 0.0 4.3 2 1 2 4 4 4 3 RsgA GTPase AIG1 PF04548.16 AIN99141.1 - 1.9e-11 43.7 0.1 1.7e-06 27.5 0.0 2.7 3 0 0 3 3 3 2 AIG1 family Roc PF08477.13 AIN99141.1 - 6.8e-11 42.4 0.0 6.8e-06 26.3 0.0 3.2 2 1 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 AIN99141.1 - 5.3e-09 35.8 0.0 0.00044 19.7 0.0 2.4 2 0 0 2 2 2 2 Signal recognition particle receptor beta subunit Ras PF00071.22 AIN99141.1 - 1.7e-08 34.2 0.0 1.5e-06 27.9 0.0 2.6 2 1 0 2 2 2 1 Ras family MMR_HSR1_Xtn PF16897.5 AIN99141.1 - 1.9e-05 24.6 0.0 0.14 12.1 0.0 3.0 3 0 0 3 3 3 2 C-terminal region of MMR_HSR1 domain cobW PF02492.19 AIN99141.1 - 0.00012 21.8 1.6 0.065 12.8 0.2 3.2 3 1 1 4 4 4 2 CobW/HypB/UreG, nucleotide-binding domain PduV-EutP PF10662.9 AIN99141.1 - 0.00046 20.0 0.0 0.28 10.9 0.0 2.7 2 1 0 2 2 2 2 Ethanolamine utilisation - propanediol utilisation T2SSE PF00437.20 AIN99141.1 - 0.0025 16.9 0.0 0.0056 15.8 0.0 1.7 1 1 0 1 1 1 1 Type II/IV secretion system protein Arf PF00025.21 AIN99141.1 - 0.0026 17.3 0.2 0.099 12.1 0.1 3.0 2 1 0 2 2 2 1 ADP-ribosylation factor family Septin PF00735.18 AIN99141.1 - 0.0039 16.5 0.0 2.1 7.5 0.0 2.4 2 0 0 2 2 2 2 Septin ABC_tran PF00005.27 AIN99141.1 - 0.004 17.7 0.0 0.11 13.0 0.0 2.4 2 0 0 2 2 2 1 ABC transporter IIGP PF05049.13 AIN99141.1 - 0.0049 16.0 0.0 0.011 14.8 0.0 1.6 1 0 0 1 1 1 1 Interferon-inducible GTPase (IIGP) TniB PF05621.11 AIN99141.1 - 0.052 13.0 0.0 0.11 11.9 0.0 1.6 1 0 0 1 1 1 0 Bacterial TniB protein CLP1_P PF16575.5 AIN99141.1 - 0.07 12.9 1.0 14 5.4 0.0 3.5 2 1 1 3 3 3 0 mRNA cleavage and polyadenylation factor CLP1 P-loop MobB PF03205.14 AIN99141.1 - 0.08 12.8 0.0 0.17 11.8 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B ELYS PF13934.6 AIN99142.1 - 0.073 13.0 0.8 0.24 11.3 0.8 1.8 1 1 0 1 1 1 0 Nuclear pore complex assembly MethyTransf_Reg PF10119.9 AIN99142.1 - 0.079 13.7 0.1 0.59 10.9 0.0 2.5 2 1 1 3 3 3 0 Predicted methyltransferase regulatory domain LRV PF01816.17 AIN99142.1 - 1.3 9.6 3.8 3.6 8.2 0.5 2.9 3 0 0 3 3 3 0 Leucine rich repeat variant NUDIX_2 PF13869.6 AIN99143.1 - 1.3e-39 135.7 0.0 1.6e-38 132.2 0.0 2.4 1 1 0 1 1 1 1 Nucleotide hydrolase Peptidase_M1 PF01433.20 AIN99144.1 - 6.7e-75 251.4 1.0 2.4e-74 249.6 0.8 1.9 2 0 0 2 2 2 1 Peptidase family M1 domain ERAP1_C PF11838.8 AIN99144.1 - 2.6e-49 168.5 0.0 4.2e-49 167.8 0.0 1.3 1 0 0 1 1 1 1 ERAP1-like C-terminal domain Peptidase_M1_N PF17900.1 AIN99144.1 - 2.8e-40 138.5 0.0 5.5e-40 137.5 0.0 1.5 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain 6PF2K PF01591.18 AIN99145.1 - 7.2e-34 117.0 0.0 1.1e-33 116.4 0.0 1.2 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.22 AIN99145.1 - 3.7e-14 52.9 0.0 2.4e-12 47.0 0.0 2.4 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Ank_5 PF13857.6 AIN99145.1 - 1.2e-12 47.8 0.1 2.6e-12 46.7 0.1 1.6 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_4 PF13637.6 AIN99145.1 - 8.1e-11 42.2 0.1 1.1e-06 29.0 0.0 2.7 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 AIN99145.1 - 1.9e-10 41.2 0.0 6.6e-10 39.4 0.0 1.9 2 0 0 2 2 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 AIN99145.1 - 1.2e-07 31.9 0.1 0.00027 21.2 0.0 3.6 3 0 0 3 3 3 1 Ankyrin repeat AAA_33 PF13671.6 AIN99145.1 - 2.8e-07 30.8 0.1 5.4e-07 29.9 0.1 1.5 1 0 0 1 1 1 1 AAA domain Ank_3 PF13606.6 AIN99145.1 - 1.7e-06 27.9 0.0 0.0022 18.3 0.0 3.5 3 0 0 3 3 3 1 Ankyrin repeat KTI12 PF08433.10 AIN99145.1 - 0.00058 19.4 0.0 0.0012 18.3 0.0 1.6 1 1 0 1 1 1 1 Chromatin associated protein KTI12 AAA_5 PF07728.14 AIN99145.1 - 0.02 14.9 0.2 0.073 13.1 0.2 1.9 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_19 PF13245.6 AIN99145.1 - 0.04 14.3 0.1 0.13 12.6 0.0 1.8 2 0 0 2 2 2 0 AAA domain APS_kinase PF01583.20 AIN99145.1 - 0.13 12.2 0.1 0.73 9.7 0.0 2.1 1 1 1 2 2 2 0 Adenylylsulphate kinase AAA_17 PF13207.6 AIN99145.1 - 0.16 12.4 0.1 0.74 10.2 0.1 2.0 1 1 0 1 1 1 0 AAA domain THF_DHG_CYH_C PF02882.19 AIN99146.1 - 5.5e-60 201.3 0.3 8.5e-60 200.7 0.3 1.3 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.23 AIN99146.1 - 3.7e-35 120.7 0.2 5.5e-35 120.1 0.2 1.3 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain Cyclin_N PF00134.23 AIN99147.1 - 1.1e-12 47.8 0.2 2.4e-12 46.7 0.1 1.6 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 AIN99147.1 - 0.0015 18.6 2.5 0.0024 18.0 0.7 2.3 2 1 0 2 2 2 1 Cyclin, C-terminal domain APC_r PF05923.12 AIN99147.1 - 0.28 11.0 2.5 20 5.0 0.0 2.8 3 0 0 3 3 3 0 APC repeat IU_nuc_hydro PF01156.19 AIN99148.1 - 6.4e-15 55.5 0.4 9.4e-15 55.0 0.4 1.3 1 1 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase Vps52 PF04129.12 AIN99149.1 - 1e-47 163.1 2.3 1.3e-14 53.8 0.0 3.4 3 1 0 3 3 3 3 Vps52 / Sac2 family DASH_Duo1 PF08651.10 AIN99149.1 - 0.0015 18.3 2.7 0.095 12.5 0.6 3.3 4 0 0 4 4 4 1 DASH complex subunit Duo1 DHR10 PF18595.1 AIN99149.1 - 0.14 12.2 0.1 0.36 10.9 0.1 1.6 1 0 0 1 1 1 0 Designed helical repeat protein 10 domain Sec3_C PF09763.9 AIN99149.1 - 0.18 10.2 0.1 2.4 6.5 0.1 2.1 2 0 0 2 2 2 0 Exocyst complex component Sec3 TPR_2 PF07719.17 AIN99151.1 - 5.2e-27 91.7 36.8 0.0009 19.2 0.1 14.8 16 1 0 16 16 15 5 Tetratricopeptide repeat TPR_1 PF00515.28 AIN99151.1 - 1.5e-24 84.7 22.3 0.002 17.9 0.0 11.1 13 0 0 13 13 12 5 Tetratricopeptide repeat TPR_12 PF13424.6 AIN99151.1 - 3.9e-19 68.7 36.2 0.0062 16.8 0.3 10.4 11 0 0 11 11 10 6 Tetratricopeptide repeat TPR_8 PF13181.6 AIN99151.1 - 8.3e-17 59.9 12.1 0.21 11.9 0.0 12.0 14 0 0 14 14 12 2 Tetratricopeptide repeat TPR_16 PF13432.6 AIN99151.1 - 8.2e-16 58.4 29.7 0.0037 17.9 0.4 9.8 8 2 0 8 8 8 3 Tetratricopeptide repeat TPR_9 PF13371.6 AIN99151.1 - 1.7e-14 53.7 28.9 0.089 12.9 0.1 10.0 7 2 2 10 10 10 5 Tetratricopeptide repeat TPR_11 PF13414.6 AIN99151.1 - 5.9e-11 41.9 6.9 0.4 10.4 0.0 7.8 8 0 0 8 8 7 3 TPR repeat TPR_14 PF13428.6 AIN99151.1 - 7.1e-09 35.8 34.6 0.064 14.1 0.4 11.7 10 3 3 13 13 12 2 Tetratricopeptide repeat TPR_19 PF14559.6 AIN99151.1 - 2.9e-08 34.1 16.3 0.067 13.7 0.0 8.9 8 2 1 9 9 9 2 Tetratricopeptide repeat TPR_17 PF13431.6 AIN99151.1 - 1.8e-05 24.8 10.0 0.5 10.9 0.1 7.1 9 0 0 9 9 6 1 Tetratricopeptide repeat TPR_10 PF13374.6 AIN99151.1 - 3.3e-05 23.6 29.5 1.9 8.5 0.9 9.3 10 0 0 10 10 9 3 Tetratricopeptide repeat TPR_6 PF13174.6 AIN99151.1 - 5.7e-05 23.5 14.8 17 6.3 0.0 9.4 10 0 0 10 10 9 0 Tetratricopeptide repeat ANAPC3 PF12895.7 AIN99151.1 - 0.00029 21.0 3.1 29 5.0 0.0 6.4 4 1 2 6 6 6 0 Anaphase-promoting complex, cyclosome, subunit 3 NARP1 PF12569.8 AIN99151.1 - 0.0029 16.6 0.2 0.45 9.4 0.0 2.8 3 0 0 3 3 3 1 NMDA receptor-regulated protein 1 ANAPC5 PF12862.7 AIN99151.1 - 0.015 15.3 5.8 1.7 8.8 0.1 5.3 5 2 0 5 5 5 0 Anaphase-promoting complex subunit 5 SHNi-TPR PF10516.9 AIN99151.1 - 0.034 13.6 8.0 1.8 8.1 0.0 5.6 7 0 0 7 7 7 0 SHNi-TPR Fis1_TPR_C PF14853.6 AIN99151.1 - 0.071 13.2 3.7 1.9 8.6 0.0 4.6 5 0 0 5 5 5 0 Fis1 C-terminal tetratricopeptide repeat TPR_7 PF13176.6 AIN99151.1 - 0.075 13.1 28.7 2.6 8.3 0.1 9.7 11 0 0 11 11 9 0 Tetratricopeptide repeat TPR_4 PF07721.14 AIN99151.1 - 5 8.1 29.5 25 5.9 0.0 9.0 9 0 0 9 9 7 0 Tetratricopeptide repeat Ist1 PF03398.14 AIN99152.1 - 2.6e-43 147.8 0.2 3.3e-43 147.5 0.2 1.1 1 0 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway Ret2_MD PF18528.1 AIN99153.1 - 1.9e-49 166.0 0.2 3.2e-49 165.2 0.2 1.4 1 0 0 1 1 1 1 RNA editing 3' terminal uridylyl transferase 2 middle domain PAP_assoc PF03828.19 AIN99153.1 - 2.2e-15 56.6 0.1 4.4e-15 55.6 0.1 1.5 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.23 AIN99153.1 - 1.4e-05 25.3 0.0 2.7e-05 24.4 0.0 1.5 1 0 0 1 1 1 1 Nucleotidyltransferase domain Polbeta PF18765.1 AIN99153.1 - 0.12 12.5 0.0 0.19 11.8 0.0 1.4 1 0 0 1 1 1 0 Polymerase beta, Nucleotidyltransferase 2OG-FeII_Oxy_2 PF13532.6 AIN99154.1 - 5.7e-12 46.2 0.0 8.4e-12 45.7 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Pan_kinase PF03309.14 AIN99154.1 - 0.091 12.6 0.0 0.17 11.7 0.0 1.3 1 0 0 1 1 1 0 Type III pantothenate kinase zf-B_box PF00643.24 AIN99155.1 - 0.0076 16.4 9.6 0.031 14.4 4.3 2.9 3 0 0 3 3 3 1 B-box zinc finger DUF1091 PF06477.13 AIN99155.1 - 0.02 15.4 0.1 0.029 14.8 0.0 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1091) DUF3090 PF11290.8 AIN99155.1 - 0.084 12.7 1.0 0.28 11.0 1.0 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF3090) zf-DNL PF05180.12 AIN99155.1 - 7.5 6.6 10.3 5.2 7.1 0.1 2.5 2 1 0 2 2 2 0 DNL zinc finger PseudoU_synth_1 PF01416.20 AIN99156.1 - 8.6e-05 23.0 0.0 0.0017 18.8 0.0 2.6 2 0 0 2 2 2 1 tRNA pseudouridine synthase ParA PF10609.9 AIN99157.1 - 2.9e-92 308.6 0.0 9.5e-91 303.6 0.0 2.0 1 1 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 AIN99157.1 - 1e-10 41.7 0.0 2e-09 37.5 0.0 2.1 2 0 0 2 2 2 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.6 AIN99157.1 - 1.8e-07 31.2 1.0 1.5e-06 28.2 1.0 2.1 1 1 0 1 1 1 1 AAA domain ArsA_ATPase PF02374.15 AIN99157.1 - 6.1e-06 25.6 0.4 4.1e-05 22.9 0.3 2.2 3 0 0 3 3 3 1 Anion-transporting ATPase MipZ PF09140.11 AIN99157.1 - 1e-05 25.0 0.2 0.00021 20.7 0.1 2.1 2 0 0 2 2 2 1 ATPase MipZ AAA_25 PF13481.6 AIN99157.1 - 0.0005 19.7 0.1 0.001 18.7 0.1 1.4 1 0 0 1 1 1 1 AAA domain Fer4_NifH PF00142.18 AIN99157.1 - 0.01 15.3 0.2 0.024 14.1 0.1 1.6 2 0 0 2 2 2 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family APS_kinase PF01583.20 AIN99157.1 - 0.022 14.6 0.0 0.041 13.8 0.0 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase NACHT PF05729.12 AIN99157.1 - 0.04 13.8 0.4 0.086 12.7 0.4 1.5 1 0 0 1 1 1 0 NACHT domain NB-ARC PF00931.22 AIN99157.1 - 0.044 13.0 0.2 0.087 12.0 0.2 1.4 1 0 0 1 1 1 0 NB-ARC domain CBP_BcsQ PF06564.12 AIN99157.1 - 0.066 12.7 0.1 0.17 11.3 0.1 1.7 1 1 0 1 1 1 0 Cellulose biosynthesis protein BcsQ MeaB PF03308.16 AIN99157.1 - 0.074 12.0 0.1 0.13 11.3 0.1 1.3 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Hpr_kinase_C PF07475.12 AIN99157.1 - 0.098 12.2 0.2 0.75 9.3 0.4 2.0 2 0 0 2 2 2 0 HPr Serine kinase C-terminal domain RNA_helicase PF00910.22 AIN99157.1 - 0.16 12.4 0.1 0.34 11.3 0.1 1.5 1 0 0 1 1 1 0 RNA helicase RsgA_GTPase PF03193.16 AIN99157.1 - 0.19 11.7 0.2 0.39 10.6 0.2 1.5 1 0 0 1 1 1 0 RsgA GTPase DUF1358 PF07096.11 AIN99158.1 - 0.00049 20.1 0.1 0.00095 19.1 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1358) ATP-synt_C PF00137.21 AIN99160.1 - 1.9e-08 34.5 12.6 3.5e-08 33.7 12.6 1.4 1 0 0 1 1 1 1 ATP synthase subunit C DUF2474 PF10617.9 AIN99161.1 - 0.066 13.1 0.3 0.18 11.7 0.3 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2474) ATP_bind_1 PF03029.17 AIN99162.1 - 4.2e-47 161.0 0.0 3.6e-45 154.6 0.0 2.7 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein AAA_33 PF13671.6 AIN99162.1 - 0.0091 16.2 0.0 0.038 14.2 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 AIN99162.1 - 0.014 15.6 0.0 0.13 12.6 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.6 AIN99162.1 - 0.049 14.1 0.9 0.45 10.9 0.3 2.5 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 AIN99162.1 - 0.056 13.9 0.0 0.63 10.5 0.0 2.5 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 AIN99162.1 - 0.092 13.3 0.3 0.092 13.3 0.3 3.0 2 2 0 2 2 2 0 AAA domain PAP_assoc PF03828.19 AIN99163.1 - 8.1e-08 32.4 0.1 1.9e-07 31.2 0.1 1.6 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.23 AIN99163.1 - 0.028 14.7 0.0 0.053 13.8 0.0 1.4 1 0 0 1 1 1 0 Nucleotidyltransferase domain LRR_6 PF13516.6 AIN99164.1 - 7.4e-32 106.7 27.5 0.0012 18.8 0.0 12.3 12 0 0 12 12 12 10 Leucine Rich repeat LRR_4 PF12799.7 AIN99164.1 - 8.1e-06 26.1 16.3 0.33 11.5 0.2 6.6 3 3 3 6 6 6 5 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 AIN99164.1 - 0.00084 19.6 10.4 75 4.5 0.4 8.1 7 3 0 7 7 7 0 Leucine Rich Repeat LRR_8 PF13855.6 AIN99164.1 - 0.0073 16.0 24.8 0.16 11.8 2.1 8.0 5 1 3 8 8 8 2 Leucine rich repeat FAA_hydrolase_N PF09298.11 AIN99164.1 - 0.11 12.7 2.9 0.11 12.6 0.5 2.1 2 1 1 3 3 3 0 Fumarylacetoacetase N-terminal DUF2652 PF10851.8 AIN99165.1 - 0.2 11.8 0.1 0.65 10.1 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2652) Glycos_transf_2 PF00535.26 AIN99167.1 - 0.0066 16.3 0.0 0.069 13.0 0.0 2.2 2 0 0 2 2 2 1 Glycosyl transferase family 2 SecG PF03840.14 AIN99167.1 - 0.11 12.6 1.4 0.21 11.7 0.1 2.1 2 0 0 2 2 2 0 Preprotein translocase SecG subunit MAPKK1_Int PF08923.10 AIN99169.1 - 0.00044 20.1 0.0 0.021 14.6 0.0 2.0 2 0 0 2 2 2 2 Mitogen-activated protein kinase kinase 1 interacting DUF525 PF04379.14 AIN99170.1 - 8.5e-16 58.0 0.0 1.9e-15 56.9 0.0 1.5 1 0 0 1 1 1 1 ApaG domain Taxilin PF09728.9 AIN99172.1 - 2.1e-07 30.5 49.0 2.8e-07 30.0 49.0 1.2 1 0 0 1 1 1 1 Myosin-like coiled-coil protein Fib_alpha PF08702.10 AIN99172.1 - 0.034 14.3 29.2 0.16 12.1 8.2 3.3 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family Laminin_II PF06009.12 AIN99172.1 - 0.43 10.6 27.1 0.23 11.5 1.5 4.0 2 1 2 4 4 4 0 Laminin Domain II Filament PF00038.21 AIN99172.1 - 2.7 7.5 47.3 0.21 11.1 20.7 2.7 1 1 2 3 3 3 0 Intermediate filament protein Lectin_N PF03954.14 AIN99172.1 - 2.9 7.7 17.6 0.5 10.1 4.4 3.8 2 2 2 4 4 4 0 Hepatic lectin, N-terminal domain Syntaxin-6_N PF09177.11 AIN99172.1 - 3 8.5 28.2 1 10.0 5.2 4.1 2 2 1 3 3 3 0 Syntaxin 6, N-terminal PPR_2 PF13041.6 AIN99173.1 - 1.8e-13 50.4 4.0 5.3e-07 29.7 0.1 4.0 2 2 2 4 4 4 4 PPR repeat family PPR_3 PF13812.6 AIN99173.1 - 1.2e-10 41.3 0.0 7.2e-06 26.0 0.0 2.7 3 0 0 3 3 3 2 Pentatricopeptide repeat domain PPR PF01535.20 AIN99173.1 - 3.6e-06 26.9 7.5 0.073 13.3 0.0 5.1 5 1 0 5 5 5 2 PPR repeat PPR_long PF17177.4 AIN99173.1 - 1.8e-05 24.2 0.2 0.0015 17.9 0.1 2.1 1 1 0 2 2 2 1 Pentacotripeptide-repeat region of PRORP PemK_toxin PF02452.17 AIN99173.1 - 0.12 12.8 0.0 0.24 11.8 0.0 1.5 1 0 0 1 1 1 0 PemK-like, MazF-like toxin of type II toxin-antitoxin system TPR_14 PF13428.6 AIN99173.1 - 0.17 12.8 0.9 52 5.1 0.1 3.6 3 1 1 4 4 4 0 Tetratricopeptide repeat MNE1 PF13762.6 AIN99173.1 - 0.18 11.8 0.2 3.8 7.5 0.0 2.7 2 1 1 3 3 3 0 Mitochondrial splicing apparatus component Cpn10 PF00166.21 AIN99174.1 - 8.2e-24 83.5 0.1 9.1e-24 83.3 0.1 1.0 1 0 0 1 1 1 1 Chaperonin 10 Kd subunit Cpn10 PF00166.21 AIN99176.1 - 8.1e-24 83.5 0.1 9.1e-24 83.3 0.1 1.0 1 0 0 1 1 1 1 Chaperonin 10 Kd subunit DUF4821 PF16092.5 AIN99177.1 - 4.3e-14 52.8 0.0 1.4e-12 47.8 0.0 2.7 1 1 0 1 1 1 1 Domain of unknown function (DUF4821) Pyr_redox_2 PF07992.14 AIN99177.1 - 3.8e-06 26.4 0.0 7.7e-06 25.3 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thioredoxin PF00085.20 AIN99178.1 - 1.4e-23 82.8 0.0 1.8e-10 40.7 0.0 2.3 2 0 0 2 2 2 2 Thioredoxin ERp29 PF07749.12 AIN99178.1 - 4.1e-16 59.7 0.0 1.1e-15 58.3 0.0 1.8 1 0 0 1 1 1 1 Endoplasmic reticulum protein ERp29, C-terminal domain OST3_OST6 PF04756.13 AIN99178.1 - 2.3e-09 37.0 0.0 5.2e-05 22.7 0.0 2.2 2 0 0 2 2 2 2 OST3 / OST6 family, transporter family HyaE PF07449.11 AIN99178.1 - 0.00019 21.4 0.1 0.75 9.8 0.0 2.6 2 0 0 2 2 2 2 Hydrogenase-1 expression protein HyaE Thioredoxin_6 PF13848.6 AIN99178.1 - 0.016 15.1 0.6 0.87 9.5 0.5 2.4 1 1 0 2 2 2 0 Thioredoxin-like domain Thioredoxin PF00085.20 AIN99179.1 - 4.6e-18 65.1 0.0 6e-18 64.7 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 AIN99179.1 - 1.7e-05 25.0 0.0 0.026 14.8 0.0 2.3 1 1 1 2 2 2 2 Thioredoxin-like OST3_OST6 PF04756.13 AIN99179.1 - 0.0012 18.3 0.0 0.0036 16.7 0.0 1.7 1 1 1 2 2 2 1 OST3 / OST6 family, transporter family Thioredoxin_2 PF13098.6 AIN99179.1 - 0.0068 16.8 0.1 0.021 15.2 0.1 1.8 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_7 PF13899.6 AIN99179.1 - 0.018 15.2 0.0 0.036 14.2 0.0 1.5 1 1 0 1 1 1 0 Thioredoxin-like TraF PF13728.6 AIN99179.1 - 0.023 14.5 0.0 0.036 13.9 0.0 1.2 1 0 0 1 1 1 0 F plasmid transfer operon protein DUF2012 PF09430.10 AIN99180.1 - 3.9e-33 114.2 0.1 5.2e-33 113.8 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2012) CarboxypepD_reg PF13620.6 AIN99180.1 - 0.0018 18.5 0.1 0.0032 17.7 0.1 1.4 1 0 0 1 1 1 1 Carboxypeptidase regulatory-like domain SpaA PF17802.1 AIN99180.1 - 0.045 14.1 0.0 0.067 13.5 0.0 1.3 1 0 0 1 1 1 0 Prealbumin-like fold domain CarbopepD_reg_2 PF13715.6 AIN99180.1 - 0.15 12.1 0.0 0.3 11.1 0.0 1.4 1 0 0 1 1 1 0 CarboxypepD_reg-like domain SNARE PF05739.19 AIN99181.1 - 2e-08 34.1 1.2 2e-08 34.1 1.2 2.2 3 0 0 3 3 3 1 SNARE domain Syntaxin-6_N PF09177.11 AIN99181.1 - 0.00046 20.7 4.4 0.00058 20.4 0.3 2.4 1 1 2 3 3 3 1 Syntaxin 6, N-terminal DUF632 PF04782.12 AIN99181.1 - 0.014 14.8 2.0 0.02 14.3 2.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF632) TBCA PF02970.16 AIN99181.1 - 0.053 13.8 0.5 0.053 13.8 0.5 2.9 2 1 1 3 3 3 0 Tubulin binding cofactor A Laminin_II PF06009.12 AIN99181.1 - 0.065 13.3 3.5 0.35 10.9 0.2 2.4 2 1 0 2 2 2 0 Laminin Domain II DASH_Duo1 PF08651.10 AIN99181.1 - 0.08 12.7 0.8 1.9 8.3 0.0 3.3 3 2 1 4 4 4 0 DASH complex subunit Duo1 PGM_PMM_II PF02879.16 AIN99181.1 - 0.083 13.5 0.2 16 6.2 0.0 2.3 2 0 0 2 2 2 0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II HHH_9 PF17674.1 AIN99181.1 - 0.13 13.2 2.1 0.35 11.8 0.1 2.5 2 1 1 3 3 3 0 HHH domain Snapin_Pallidin PF14712.6 AIN99181.1 - 0.2 12.1 8.3 2.6 8.5 1.5 2.8 2 1 0 2 2 2 0 Snapin/Pallidin T3SSipB PF16535.5 AIN99181.1 - 0.29 11.6 5.8 0.54 10.7 0.1 2.3 1 1 1 2 2 2 0 Type III cell invasion protein SipB CheZ PF04344.13 AIN99181.1 - 0.31 10.9 9.5 0.37 10.7 7.3 1.9 1 1 1 2 2 2 0 Chemotaxis phosphatase, CheZ DUF2951 PF11166.8 AIN99181.1 - 0.49 10.7 6.4 0.098 12.9 1.3 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF2951) DHR10 PF18595.1 AIN99181.1 - 2 8.5 14.8 0.77 9.8 0.1 3.0 1 1 2 3 3 3 0 Designed helical repeat protein 10 domain Fib_alpha PF08702.10 AIN99181.1 - 3.5 7.8 8.4 4.4 7.5 5.1 2.4 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family Pentapeptide_4 PF13599.6 AIN99182.1 - 5.1e-08 33.0 3.7 9.7e-07 28.9 0.2 3.3 2 1 1 3 3 3 2 Pentapeptide repeats (9 copies) Pentapeptide PF00805.22 AIN99182.1 - 1.7e-06 27.5 0.0 1.7e-06 27.5 0.0 4.0 5 0 0 5 5 5 1 Pentapeptide repeats (8 copies) Pentapeptide_3 PF13576.6 AIN99182.1 - 8.5e-05 22.6 0.0 0.0016 18.5 0.1 4.0 2 1 2 4 4 4 3 Pentapeptide repeats (9 copies) DAGK_cat PF00781.24 AIN99183.1 - 1.8e-12 46.9 0.6 1e-10 41.3 0.0 2.9 3 0 0 3 3 3 2 Diacylglycerol kinase catalytic domain DUF1064 PF06356.11 AIN99183.1 - 0.18 12.2 0.0 0.33 11.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1064) RCC1 PF00415.18 AIN99186.1 - 3.2e-71 235.8 47.9 1.7e-16 60.6 0.5 12.5 11 2 0 11 11 11 10 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 AIN99186.1 - 1.7e-35 120.1 76.7 4.4e-07 29.5 0.0 11.3 12 0 0 12 12 12 7 Regulator of chromosome condensation (RCC1) repeat Hira PF07569.11 AIN99186.1 - 0.086 12.6 0.4 16 5.2 0.0 3.2 3 0 0 3 3 3 0 TUP1-like enhancer of split GAD-like PF08887.11 AIN99186.1 - 0.13 12.0 0.3 23 4.8 0.1 3.4 3 0 0 3 3 3 0 GAD-like domain Methyltransf_9 PF08003.11 AIN99186.1 - 0.2 10.5 0.1 8.3 5.2 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1698) RCC1 PF00415.18 AIN99187.1 - 5.7e-62 206.1 34.4 4.4e-12 46.4 0.3 12.6 12 0 0 12 12 12 10 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 AIN99187.1 - 1.4e-29 101.2 58.7 2.3e-05 24.1 0.4 12.5 13 0 0 13 13 13 9 Regulator of chromosome condensation (RCC1) repeat Hira PF07569.11 AIN99187.1 - 0.0058 16.4 0.0 0.16 11.7 0.0 2.9 3 0 0 3 3 3 1 TUP1-like enhancer of split DUF4213 PF13938.6 AIN99187.1 - 0.88 9.8 6.9 2.2 8.6 0.2 4.2 4 0 0 4 4 4 0 Putative heavy-metal chelation RRM_1 PF00076.22 AIN99188.1 - 3.3e-11 42.8 0.0 4.9e-11 42.3 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.22 AIN99190.1 - 5.8e-06 26.0 0.0 8.2e-05 22.4 0.0 2.1 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) GSHPx PF00255.19 AIN99192.1 - 1.3e-22 79.4 0.1 1.8e-22 79.0 0.1 1.2 1 0 0 1 1 1 1 Glutathione peroxidase GSHPx PF00255.19 AIN99193.1 - 1.7e-38 130.5 0.6 2.1e-38 130.2 0.6 1.1 1 0 0 1 1 1 1 Glutathione peroxidase AhpC-TSA PF00578.21 AIN99193.1 - 4.6e-06 26.6 0.1 8.3e-06 25.7 0.1 1.5 2 0 0 2 2 2 1 AhpC/TSA family Redoxin PF08534.10 AIN99193.1 - 7.1e-05 22.6 0.0 0.00059 19.6 0.0 2.0 2 0 0 2 2 2 1 Redoxin GSHPx PF00255.19 AIN99194.1 - 1.4e-38 130.8 0.6 1.8e-38 130.4 0.6 1.1 1 0 0 1 1 1 1 Glutathione peroxidase AhpC-TSA PF00578.21 AIN99194.1 - 5e-06 26.4 0.1 9.8e-06 25.5 0.1 1.5 2 0 0 2 2 2 1 AhpC/TSA family Redoxin PF08534.10 AIN99194.1 - 0.00013 21.7 0.0 0.0011 18.7 0.0 2.0 2 0 0 2 2 2 1 Redoxin AsnA PF03590.15 AIN99195.1 - 4.8e-95 317.6 0.0 6e-95 317.3 0.0 1.1 1 0 0 1 1 1 1 Aspartate-ammonia ligase tRNA-synt_2 PF00152.20 AIN99195.1 - 0.0051 15.9 0.1 0.011 14.8 0.1 1.5 2 0 0 2 2 2 1 tRNA synthetases class II (D, K and N) BUD22 PF09073.10 AIN99196.1 - 4 6.7 15.0 7.9 5.7 15.0 1.4 1 0 0 1 1 1 0 BUD22 Anophelin PF10731.9 AIN99196.1 - 5.2 7.0 5.8 2 8.3 0.7 2.8 3 0 0 3 3 3 0 Thrombin inhibitor from mosquito IF3_N PF05198.16 AIN99197.1 - 0.06 13.6 0.0 0.12 12.6 0.0 1.5 1 0 0 1 1 1 0 Translation initiation factor IF-3, N-terminal domain Exo_endo_phos PF03372.23 AIN99198.1 - 1.7e-06 27.7 0.0 2e-05 24.2 0.0 2.4 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family XRN_N PF03159.18 AIN99198.1 - 0.00025 20.6 0.0 0.00067 19.2 0.0 1.7 2 0 0 2 2 2 1 XRN 5'-3' exonuclease N-terminus Ribosomal_S9 PF00380.19 AIN99200.1 - 1.6e-26 93.2 0.9 1.8e-26 93.0 0.9 1.0 1 0 0 1 1 1 1 Ribosomal protein S9/S16 HSP70 PF00012.20 AIN99201.1 - 2.3e-76 257.3 0.0 3.2e-39 134.6 0.0 2.4 2 0 0 2 2 2 2 Hsp70 protein MreB_Mbl PF06723.13 AIN99201.1 - 0.00021 20.2 0.0 0.22 10.3 0.1 3.1 2 1 1 3 3 3 2 MreB/Mbl protein OGFr_N PF04664.13 AIN99202.1 - 1.5e-07 31.2 0.4 0.00045 19.8 0.0 2.2 2 0 0 2 2 2 2 Opioid growth factor receptor (OGFr) conserved region DNA_pol3_delt_C PF14840.6 AIN99202.1 - 0.083 13.2 0.0 0.15 12.4 0.0 1.4 1 0 0 1 1 1 0 Processivity clamp loader gamma complex DNA pol III C-term PIF1 PF05970.14 AIN99204.1 - 2.7e-05 23.5 0.0 4.9e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 PIF1-like helicase IstB_IS21 PF01695.17 AIN99204.1 - 0.00027 20.7 0.1 0.0025 17.6 0.0 2.3 2 0 0 2 2 2 1 IstB-like ATP binding protein SRP54 PF00448.22 AIN99204.1 - 0.0049 16.5 0.0 0.0092 15.6 0.0 1.3 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain Viral_env_E26 PF11050.8 AIN99204.1 - 0.04 13.3 0.0 0.07 12.5 0.0 1.3 1 0 0 1 1 1 0 Virus envelope protein E26 Bac_DnaA PF00308.18 AIN99204.1 - 0.077 12.8 0.0 0.28 11.0 0.0 1.8 2 0 0 2 2 2 0 Bacterial dnaA protein DUF815 PF05673.13 AIN99204.1 - 0.16 11.1 0.0 0.28 10.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Nitro_FeMo-Co PF02579.17 AIN99204.1 - 0.19 12.1 0.1 0.42 11.0 0.1 1.5 1 0 0 1 1 1 0 Dinitrogenase iron-molybdenum cofactor Sgf11 PF08209.11 AIN99204.1 - 1.5 8.5 5.8 4.8 6.8 0.3 3.2 3 0 0 3 3 3 0 Sgf11 (transcriptional regulation protein) DUF3395 PF11875.8 AIN99205.1 - 6.4e-42 143.1 0.0 1.1e-41 142.3 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3395) DnaJ PF00226.31 AIN99205.1 - 1.3e-15 57.3 0.1 2.1e-15 56.6 0.1 1.4 1 0 0 1 1 1 1 DnaJ domain Mcp5_PH PF12814.7 AIN99206.1 - 1.4e-22 80.1 2.3 3e-22 79.0 2.3 1.6 1 0 0 1 1 1 1 Meiotic cell cortex C-terminal pleckstrin homology LcrR PF09621.10 AIN99206.1 - 0.16 11.4 0.4 0.42 10.1 0.2 1.7 2 0 0 2 2 2 0 Type III secretion system regulator (LcrR) NMD3 PF04981.13 AIN99208.1 - 3.6e-76 255.8 2.5 3.6e-76 255.8 2.5 1.4 2 0 0 2 2 2 1 NMD3 family DZR PF12773.7 AIN99208.1 - 2.3 8.3 12.0 2.1 8.4 3.9 2.8 2 1 1 3 3 3 0 Double zinc ribbon Pkinase PF00069.25 AIN99209.1 - 1.9e-29 102.9 0.0 5.6e-29 101.3 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 AIN99209.1 - 6e-12 45.4 0.0 4.3e-06 26.2 0.0 2.6 2 0 0 2 2 2 2 Protein tyrosine kinase Pox_ser-thr_kin PF05445.11 AIN99209.1 - 0.26 10.2 0.0 0.38 9.7 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase PRKCSH-like PF12999.7 AIN99210.1 - 1.2e-37 129.4 1.5 2.1e-37 128.6 1.5 1.4 1 0 0 1 1 1 1 Glucosidase II beta subunit-like PRKCSH_1 PF13015.6 AIN99210.1 - 1e-17 64.3 0.0 2.2e-17 63.1 0.0 1.6 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein PRKCSH PF07915.13 AIN99210.1 - 9.5e-07 29.7 0.1 2.3e-06 28.5 0.1 1.7 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein FTA4 PF13093.6 AIN99210.1 - 0.033 14.1 0.0 0.062 13.2 0.0 1.4 2 0 0 2 2 2 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 DUF2682 PF10909.8 AIN99212.1 - 0.11 13.0 0.0 0.13 12.8 0.0 1.2 1 1 0 1 1 1 0 Protein of unknown function (DUF2682) AAA_6 PF12774.7 AIN99213.1 - 1.9e-152 507.0 0.0 2.3e-151 503.4 0.0 2.5 2 0 0 2 2 2 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 AIN99213.1 - 3.2e-116 388.7 6.5 3.2e-116 388.7 6.5 3.8 4 0 0 4 4 4 1 Dynein heavy chain, N-terminal region 2 AAA_8 PF12780.7 AIN99213.1 - 3e-99 331.6 0.4 8.8e-99 330.0 0.0 2.1 2 0 0 2 2 2 1 P-loop containing dynein motor region D4 Dynein_C PF18199.1 AIN99213.1 - 6.3e-95 317.9 0.1 2.7e-94 315.8 0.0 2.1 2 0 0 2 2 2 1 Dynein heavy chain C-terminal domain AAA_9 PF12781.7 AIN99213.1 - 6.7e-85 283.7 0.4 6.7e-85 283.7 0.4 2.7 3 0 0 3 3 3 1 ATP-binding dynein motor region AAA_7 PF12775.7 AIN99213.1 - 5.8e-54 182.4 0.0 2.4e-49 167.3 0.0 3.7 3 0 0 3 3 3 2 P-loop containing dynein motor region AAA_lid_11 PF18198.1 AIN99213.1 - 3e-52 176.7 0.0 8.1e-52 175.3 0.0 1.8 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain MT PF12777.7 AIN99213.1 - 3.7e-51 174.2 5.9 7.8e-51 173.1 5.9 1.5 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor Dynein_heavy PF03028.15 AIN99213.1 - 6.5e-40 135.9 0.0 5.4e-37 126.5 0.0 3.7 3 0 0 3 3 3 1 Dynein heavy chain region D6 P-loop domain AAA_5 PF07728.14 AIN99213.1 - 2.9e-24 85.6 0.0 2.5e-06 27.6 0.0 5.7 4 1 0 4 4 4 4 AAA domain (dynein-related subfamily) Dynein_AAA_lid PF17852.1 AIN99213.1 - 4.7e-18 65.5 0.1 1.3e-16 60.8 0.0 3.5 2 1 0 2 2 2 1 Dynein heavy chain AAA lid domain AAA_lid_1 PF17857.1 AIN99213.1 - 9.3e-17 61.1 0.0 4e-16 59.1 0.0 2.2 1 0 0 1 1 1 1 AAA+ lid domain AAA PF00004.29 AIN99213.1 - 5.9e-06 26.7 0.0 1.6 9.2 0.0 5.0 4 0 0 4 4 4 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 AIN99213.1 - 6.3e-06 26.5 1.9 8.8 6.6 0.0 5.9 6 0 0 6 6 5 1 AAA domain FtsK_SpoIIIE PF01580.18 AIN99213.1 - 8.7e-06 25.3 0.7 0.0019 17.6 0.0 3.5 3 0 0 3 3 3 1 FtsK/SpoIIIE family AAA_16 PF13191.6 AIN99213.1 - 1.6e-05 25.4 14.7 2.5 8.4 0.0 7.6 6 2 0 7 7 7 2 AAA ATPase domain AAA_30 PF13604.6 AIN99213.1 - 0.0038 17.0 1.6 2.4 7.8 0.2 3.9 3 0 0 3 3 3 1 AAA domain RNA_helicase PF00910.22 AIN99213.1 - 0.011 16.1 0.0 4.4 7.7 0.0 4.3 4 0 0 4 4 4 0 RNA helicase Aldo_ket_red PF00248.21 AIN99214.1 - 4.9e-05 22.7 0.0 0.073 12.3 0.0 2.4 2 0 0 2 2 2 2 Aldo/keto reductase family Peptidase_M28 PF04389.17 AIN99215.1 - 9.4e-05 22.2 0.1 0.00023 20.9 0.1 1.6 2 0 0 2 2 2 1 Peptidase family M28 Arfaptin PF06456.13 AIN99215.1 - 0.044 13.4 1.0 0.07 12.7 0.2 1.7 2 0 0 2 2 2 0 Arfaptin-like domain Fer2 PF00111.27 AIN99216.1 - 1.3e-12 47.5 1.0 1.9e-12 46.9 1.0 1.2 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain RRM_1 PF00076.22 AIN99217.1 - 1.1e-07 31.5 0.0 1.9e-07 30.8 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Btz PF09405.10 AIN99217.1 - 0.094 13.0 0.3 0.2 11.9 0.0 1.7 2 0 0 2 2 2 0 CASC3/Barentsz eIF4AIII binding TROVE PF05731.11 AIN99222.1 - 2.9e-61 207.9 0.6 2.6e-33 115.7 0.0 2.5 2 0 0 2 2 2 2 TROVE domain WD40 PF00400.32 AIN99222.1 - 7.5e-12 45.6 15.9 0.0083 17.0 0.1 9.7 10 0 0 10 10 10 3 WD domain, G-beta repeat DUF4062 PF13271.6 AIN99222.1 - 5e-11 42.8 0.0 1.6e-10 41.2 0.0 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4062) Ax_dynein_light PF10211.9 AIN99223.1 - 5.3e-42 143.9 2.1 7.9e-42 143.3 2.1 1.2 1 0 0 1 1 1 1 Axonemal dynein light chain PrpR_N PF06506.11 AIN99225.1 - 0.0082 15.7 0.1 0.051 13.1 0.1 2.1 2 0 0 2 2 2 1 Propionate catabolism activator TRAPP PF04051.16 AIN99225.1 - 0.041 13.6 0.0 0.11 12.2 0.0 1.7 1 1 0 1 1 1 0 Transport protein particle (TRAPP) component Smoa_sbd PF17885.1 AIN99225.1 - 0.14 12.3 0.0 0.36 10.9 0.0 1.7 1 0 0 1 1 1 0 Styrene monooxygenase A putative substrate binding domain PseudoU_synth_2 PF00849.22 AIN99227.1 - 1.8e-14 54.2 0.0 5.6e-07 29.8 0.0 3.7 2 2 0 2 2 2 2 RNA pseudouridylate synthase zf-RING_2 PF13639.6 AIN99228.1 - 1.9e-05 24.9 2.3 1.9e-05 24.9 2.3 2.9 3 0 0 3 3 3 2 Ring finger domain zf-C3HC4_3 PF13920.6 AIN99228.1 - 0.00018 21.3 2.3 0.00018 21.3 2.3 3.0 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 AIN99228.1 - 0.0014 18.4 1.0 0.0014 18.4 1.0 2.7 3 0 0 3 3 3 1 Prokaryotic RING finger family 4 zf-RING_11 PF17123.5 AIN99228.1 - 0.0024 17.6 2.1 0.21 11.4 0.0 2.8 2 0 0 2 2 2 1 RING-like zinc finger zf-C3HC4 PF00097.25 AIN99228.1 - 0.0047 16.8 2.1 0.0047 16.8 2.1 3.0 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 AIN99228.1 - 0.0087 16.0 1.5 0.0087 16.0 1.5 3.1 3 0 0 3 3 3 1 zinc-RING finger domain Baculo_IE-1 PF05290.11 AIN99228.1 - 0.021 14.8 0.4 0.054 13.5 0.4 1.6 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) GOLGA2L5 PF15070.6 AIN99228.1 - 0.024 13.3 6.5 0.035 12.8 6.5 1.1 1 0 0 1 1 1 0 Putative golgin subfamily A member 2-like protein 5 Prefoldin_2 PF01920.20 AIN99228.1 - 0.11 12.5 0.5 0.24 11.4 0.5 1.5 1 0 0 1 1 1 0 Prefoldin subunit Snapin_Pallidin PF14712.6 AIN99228.1 - 0.88 10.0 5.0 0.85 10.1 0.8 2.2 2 0 0 2 2 2 0 Snapin/Pallidin Beta_helix PF13229.6 AIN99229.1 - 0.00041 20.2 0.0 1.1 9.1 0.0 2.5 2 0 0 2 2 2 2 Right handed beta helix region DnaJ PF00226.31 AIN99231.1 - 3.3e-20 72.0 0.2 6.7e-20 71.0 0.2 1.6 1 0 0 1 1 1 1 DnaJ domain DnaJ-X PF14308.6 AIN99231.1 - 0.00033 20.1 0.1 0.0018 17.8 0.0 2.2 2 0 0 2 2 2 1 X-domain of DnaJ-containing Aldo_ket_red PF00248.21 AIN99232.1 - 8.1e-28 97.5 0.0 2.3e-24 86.1 0.0 2.7 2 1 0 2 2 2 2 Aldo/keto reductase family DUF3037 PF11236.8 AIN99232.1 - 0.14 12.6 0.0 0.28 11.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3037) LRR_4 PF12799.7 AIN99233.1 - 2.8e-11 43.4 2.0 9.3e-05 22.7 0.2 4.0 4 0 0 4 4 4 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 AIN99233.1 - 6.7e-10 38.6 3.4 0.0052 16.5 5.1 4.3 3 1 0 3 3 3 2 Leucine rich repeat LRR_6 PF13516.6 AIN99233.1 - 0.00014 21.7 3.3 0.92 9.7 0.0 3.8 4 0 0 4 4 4 2 Leucine Rich repeat LRR_9 PF14580.6 AIN99233.1 - 0.00044 19.8 0.0 0.0011 18.5 0.0 1.6 2 0 0 2 2 2 1 Leucine-rich repeat LRR_1 PF00560.33 AIN99233.1 - 0.022 15.3 11.1 26 5.9 0.5 5.8 6 0 0 6 6 6 0 Leucine Rich Repeat PTCB-BRCT PF12738.7 AIN99234.1 - 7.5e-05 22.6 0.3 2.2 8.3 0.0 3.9 3 0 0 3 3 3 3 twin BRCT domain BRCT PF00533.26 AIN99234.1 - 0.0022 18.4 0.0 13 6.3 0.0 4.2 4 0 0 4 4 4 1 BRCA1 C Terminus (BRCT) domain Nup54 PF13874.6 AIN99234.1 - 0.29 11.3 6.0 0.77 9.9 6.0 1.7 1 0 0 1 1 1 0 Nucleoporin complex subunit 54 HSP70 PF00012.20 AIN99235.1 - 2.4e-244 812.1 6.5 2.7e-244 811.9 6.5 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 AIN99235.1 - 1e-18 67.3 0.5 5.7e-17 61.5 0.1 2.4 2 0 0 2 2 2 2 MreB/Mbl protein Hydantoinase_A PF01968.18 AIN99235.1 - 0.0036 16.6 1.4 0.0079 15.5 0.2 2.2 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase FtsA PF14450.6 AIN99235.1 - 0.0097 16.3 2.9 5.1 7.6 0.1 3.5 3 2 0 3 3 3 2 Cell division protein FtsA FYVE PF01363.21 AIN99237.1 - 2.4e-14 53.2 1.5 2.4e-14 53.2 1.5 2.7 2 0 0 2 2 2 1 FYVE zinc finger DnaJ PF00226.31 AIN99238.1 - 5e-21 74.6 0.1 1.2e-20 73.3 0.1 1.7 1 0 0 1 1 1 1 DnaJ domain DnaJ-X PF14308.6 AIN99238.1 - 1.1e-08 34.8 0.0 0.00042 19.8 0.1 2.4 2 0 0 2 2 2 2 X-domain of DnaJ-containing DUF1999 PF09390.10 AIN99238.1 - 0.046 13.4 0.0 0.13 11.9 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1999) Cupin_8 PF13621.6 AIN99240.1 - 4.9e-57 193.5 0.0 8.5e-56 189.5 0.0 2.2 1 1 0 1 1 1 1 Cupin-like domain Fer2_2 PF01799.20 AIN99244.1 - 0.072 13.1 0.2 0.31 11.1 0.2 2.0 1 1 0 1 1 1 0 [2Fe-2S] binding domain DNA_ligase_OB_2 PF14743.6 AIN99245.1 - 3.2e-19 68.7 0.0 8.4e-19 67.4 0.0 1.8 1 0 0 1 1 1 1 DNA ligase OB-like domain DUF4379 PF14311.6 AIN99245.1 - 8.7e-14 51.6 2.3 2.7e-13 50.0 2.3 1.9 1 0 0 1 1 1 1 Probable Zinc-ribbon domain DNA_ligase_A_M PF01068.21 AIN99245.1 - 6.3e-11 42.3 0.0 6.7e-08 32.4 0.0 3.0 1 1 1 2 2 2 1 ATP dependent DNA ligase domain mRNA_cap_enzyme PF01331.19 AIN99245.1 - 0.01 15.7 0.0 0.48 10.2 0.0 2.3 2 0 0 2 2 2 0 mRNA capping enzyme, catalytic domain Vps36-NZF-N PF16988.5 AIN99245.1 - 0.022 14.1 0.2 0.045 13.1 0.2 1.5 1 0 0 1 1 1 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain PhnA_Zn_Ribbon PF08274.12 AIN99245.1 - 0.045 13.7 2.9 1.1 9.3 1.3 2.4 2 0 0 2 2 2 0 PhnA Zinc-Ribbon Zn-ribbon_8 PF09723.10 AIN99245.1 - 0.086 13.0 1.0 0.2 11.8 1.0 1.6 1 0 0 1 1 1 0 Zinc ribbon domain zf-RRN7 PF11781.8 AIN99245.1 - 0.2 11.4 4.0 5.6 6.7 0.5 2.5 2 0 0 2 2 2 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 zf-HYPF PF07503.12 AIN99245.1 - 0.25 11.2 1.9 0.48 10.3 1.9 1.5 1 0 0 1 1 1 0 HypF finger Rubredoxin_2 PF18073.1 AIN99245.1 - 2.7 7.8 7.1 4.8 7.0 1.2 2.5 2 0 0 2 2 2 0 Rubredoxin metal binding domain Zn_ribbon_SprT PF17283.2 AIN99245.1 - 7.8 6.5 9.2 8.3 6.4 6.6 2.4 2 1 1 3 3 3 0 SprT-like zinc ribbon domain DNA_ligase_A_M PF01068.21 AIN99246.1 - 3e-19 69.5 0.0 1.1e-18 67.6 0.0 1.9 1 1 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_OB_2 PF14743.6 AIN99246.1 - 8.3e-15 54.6 0.0 1.6e-14 53.7 0.0 1.5 1 0 0 1 1 1 1 DNA ligase OB-like domain mRNA_cap_enzyme PF01331.19 AIN99246.1 - 0.00037 20.4 0.0 1.1 9.0 0.0 3.2 2 2 0 2 2 2 2 mRNA capping enzyme, catalytic domain DUF4379 PF14311.6 AIN99246.1 - 0.0027 18.0 7.4 0.0064 16.8 7.4 1.7 1 0 0 1 1 1 1 Probable Zinc-ribbon domain Zn-ribbon_8 PF09723.10 AIN99246.1 - 0.0036 17.4 0.7 0.011 15.8 0.7 1.9 1 0 0 1 1 1 1 Zinc ribbon domain Zn_Tnp_IS1595 PF12760.7 AIN99246.1 - 0.99 9.4 3.9 2.5 8.1 0.1 2.5 2 0 0 2 2 2 0 Transposase zinc-ribbon domain Thioredoxin PF00085.20 AIN99247.1 - 0.01 15.8 0.1 0.37 10.8 0.0 2.6 2 0 0 2 2 2 0 Thioredoxin Peptidase_M16 PF00675.20 AIN99247.1 - 0.058 13.4 0.0 0.13 12.2 0.0 1.6 1 0 0 1 1 1 0 Insulinase (Peptidase family M16) MMR_HSR1 PF01926.23 AIN99248.1 - 5.2e-15 55.5 0.0 3.1e-13 49.8 0.0 2.4 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 AIN99248.1 - 2.1e-06 27.3 0.0 0.00032 20.3 0.0 2.2 2 0 0 2 2 2 2 Ferrous iron transport protein B RsgA_GTPase PF03193.16 AIN99248.1 - 0.00013 21.9 0.0 0.0071 16.3 0.0 2.4 2 0 0 2 2 2 1 RsgA GTPase GTP_EFTU PF00009.27 AIN99248.1 - 0.0017 17.9 0.0 2.3 7.7 0.0 3.0 2 1 0 2 2 2 2 Elongation factor Tu GTP binding domain Dynamin_N PF00350.23 AIN99248.1 - 0.0043 17.1 1.1 0.1 12.7 0.2 2.7 1 1 1 2 2 2 1 Dynamin family Rib_recp_KP_reg PF05104.12 AIN99248.1 - 1.8 9.6 10.3 1 10.4 4.5 2.8 2 0 0 2 2 2 0 Ribosome receptor lysine/proline rich region Prefoldin PF02996.17 AIN99249.1 - 8.9e-26 90.2 1.9 1.2e-25 89.8 1.3 1.5 1 1 0 1 1 1 1 Prefoldin subunit End3 PF12761.7 AIN99249.1 - 0.031 14.5 2.9 1.4 9.0 0.8 2.3 2 0 0 2 2 2 0 Actin cytoskeleton-regulatory complex protein END3 TPR_12 PF13424.6 AIN99249.1 - 0.092 13.0 1.7 0.57 10.5 0.2 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat YabA PF06156.13 AIN99249.1 - 0.17 12.5 4.7 14 6.4 3.5 2.3 2 0 0 2 2 2 0 Initiation control protein YabA WD40 PF00400.32 AIN99251.1 - 3.1e-15 56.3 12.9 0.001 19.8 0.2 6.9 7 0 0 7 7 7 5 WD domain, G-beta repeat WWE PF02825.20 AIN99251.1 - 8.8e-12 45.5 1.0 3.2e-11 43.7 1.0 2.0 1 1 0 1 1 1 1 WWE domain ANAPC4_WD40 PF12894.7 AIN99251.1 - 0.0015 18.8 0.1 2.2 8.6 0.0 3.6 2 2 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain DnaJ PF00226.31 AIN99252.1 - 4.2e-18 65.2 1.8 4.6e-18 65.1 0.4 1.8 2 0 0 2 2 2 1 DnaJ domain DUF3180 PF11377.8 AIN99252.1 - 0.019 15.1 6.3 0.027 14.6 0.3 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3180) MORN PF02493.20 AIN99253.1 - 1.1e-39 132.0 132.4 0.00012 21.8 0.5 24.2 27 0 0 27 27 27 18 MORN repeat FYVE PF01363.21 AIN99253.1 - 8.2e-26 89.9 15.5 1.5e-18 66.7 4.8 2.7 2 0 0 2 2 2 2 FYVE zinc finger zf-CRD PF17979.1 AIN99253.1 - 2.1 8.5 13.7 4.6 7.3 2.4 2.7 2 0 0 2 2 2 0 Cysteine rich domain with multizinc binding regions Cyt-b5 PF00173.28 AIN99254.1 - 5.1e-18 65.0 0.0 9.8e-18 64.1 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Ribosomal_L29 PF00831.23 AIN99256.1 - 0.041 13.8 0.6 0.16 12.0 0.6 2.0 1 0 0 1 1 1 0 Ribosomal L29 protein CYYR1 PF10873.8 AIN99257.1 - 0.022 15.2 0.0 0.022 15.2 0.0 2.4 3 0 0 3 3 3 0 Cysteine and tyrosine-rich protein 1 Prenyltrans PF00432.21 AIN99258.1 - 2.5e-22 78.3 13.6 5.2e-05 22.9 0.2 5.9 5 0 0 5 5 5 5 Prenyltransferase and squalene oxidase repeat SQHop_cyclase_N PF13249.6 AIN99258.1 - 0.095 11.8 0.0 0.23 10.5 0.0 1.6 1 0 0 1 1 1 0 Squalene-hopene cyclase N-terminal domain COG7 PF10191.9 AIN99259.1 - 1.2e-09 37.1 12.9 0.00072 17.9 1.7 5.1 5 0 0 5 5 5 5 Golgi complex component 7 (COG7) DUF4378 PF14309.6 AIN99259.1 - 0.079 13.3 1.3 2.1 8.7 0.2 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF4378) FEZ PF07763.13 AIN99259.1 - 0.16 11.7 3.6 0.84 9.3 0.0 2.8 2 1 0 2 2 2 0 FEZ-like protein zf-ZPR1 PF03367.13 AIN99259.1 - 0.32 10.9 3.4 12 5.8 0.0 2.8 3 0 0 3 3 3 0 ZPR1 zinc-finger domain DUF948 PF06103.11 AIN99259.1 - 4.5 7.6 11.7 4.2 7.7 0.1 4.4 5 0 0 5 5 5 0 Bacterial protein of unknown function (DUF948) PhoD PF09423.10 AIN99260.1 - 0.0014 17.7 0.0 0.031 13.3 0.0 2.4 2 1 0 2 2 2 1 PhoD-like phosphatase Abhydrolase_6 PF12697.7 AIN99263.1 - 7.3e-12 46.4 1.9 1.2e-11 45.7 1.9 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 AIN99263.1 - 3.3e-05 23.3 0.7 0.03 13.6 0.0 3.9 3 1 0 3 3 3 1 Serine aminopeptidase, S33 DUF915 PF06028.11 AIN99263.1 - 0.0025 17.2 0.0 0.0086 15.4 0.0 1.7 2 0 0 2 2 2 1 Alpha/beta hydrolase of unknown function (DUF915) Abhydrolase_1 PF00561.20 AIN99263.1 - 0.0026 17.4 0.7 0.041 13.5 0.4 2.6 2 1 0 2 2 2 1 alpha/beta hydrolase fold RRM_1 PF00076.22 AIN99264.1 - 4.1e-16 58.6 0.0 6.6e-16 57.9 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 AIN99264.1 - 1.6e-05 24.5 0.0 2.6e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 AIN99264.1 - 0.0031 17.6 0.0 0.0078 16.3 0.0 1.7 1 1 0 1 1 1 1 RNA recognition motif PHM7_cyt PF14703.6 AIN99264.1 - 0.076 13.3 0.1 1.7 8.8 0.1 2.2 1 1 1 2 2 2 0 Cytosolic domain of 10TM putative phosphate transporter Glutaredoxin PF00462.24 AIN99265.1 - 9e-07 29.0 0.0 2.1e-06 27.8 0.0 1.6 1 0 0 1 1 1 1 Glutaredoxin GST_N_3 PF13417.6 AIN99265.1 - 2e-05 24.9 0.0 6.8e-05 23.2 0.0 1.9 2 1 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 AIN99265.1 - 0.037 14.3 0.0 0.14 12.4 0.0 2.1 1 1 0 1 1 1 0 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 AIN99265.1 - 0.08 13.3 0.0 0.31 11.4 0.0 2.0 2 0 0 2 2 2 0 Glutathione S-transferase, N-terminal domain DUF836 PF05768.14 AIN99265.1 - 0.09 13.2 0.0 0.16 12.4 0.0 1.4 1 0 0 1 1 1 0 Glutaredoxin-like domain (DUF836) GST_C_4 PF14834.6 AIN99265.1 - 0.16 12.3 0.0 0.28 11.6 0.0 1.3 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain 3HCDH_N PF02737.18 AIN99266.1 - 4.4e-51 173.3 3.6 7.8e-51 172.5 3.6 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.22 AIN99266.1 - 7.7e-33 113.0 0.1 2.2e-22 79.4 0.0 3.1 3 0 0 3 3 3 2 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain ECH_1 PF00378.20 AIN99266.1 - 1.1e-31 110.1 0.3 1.1e-31 110.1 0.3 2.0 2 1 0 2 2 2 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 AIN99266.1 - 2e-21 76.9 0.1 5.3e-21 75.5 0.1 1.7 2 0 0 2 2 2 1 Enoyl-CoA hydratase/isomerase NAD_binding_2 PF03446.15 AIN99266.1 - 0.00029 21.1 1.8 0.00049 20.3 0.5 2.1 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase Shikimate_DH PF01488.20 AIN99266.1 - 0.0031 17.6 1.2 0.54 10.3 0.2 2.6 2 0 0 2 2 2 2 Shikimate / quinate 5-dehydrogenase Sacchrp_dh_NADP PF03435.18 AIN99266.1 - 0.073 13.3 1.0 0.26 11.5 0.5 2.3 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain AlaDh_PNT_C PF01262.21 AIN99266.1 - 0.33 10.2 4.0 0.64 9.3 1.3 2.1 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain F420_oxidored PF03807.17 AIN99266.1 - 0.36 11.4 2.1 0.75 10.4 1.0 2.3 2 1 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent SNF2_N PF00176.23 AIN99267.1 - 2.9e-28 98.6 0.3 1.4e-18 66.7 0.0 3.2 3 0 0 3 3 3 3 SNF2 family N-terminal domain zf-RING_2 PF13639.6 AIN99267.1 - 7.6e-07 29.4 7.6 1.7e-06 28.2 4.8 3.1 2 0 0 2 2 2 1 Ring finger domain zf-RING_UBOX PF13445.6 AIN99267.1 - 9.6e-07 28.7 1.6 9.6e-07 28.7 1.6 2.5 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4 PF00097.25 AIN99267.1 - 1.2e-06 28.3 5.5 4.1e-06 26.6 5.5 2.0 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 AIN99267.1 - 3.3e-06 26.9 5.9 3.3e-06 26.9 5.9 2.9 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) Helicase_C PF00271.31 AIN99267.1 - 4.5e-06 27.0 0.0 9.1e-06 26.0 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-C3HC4_2 PF13923.6 AIN99267.1 - 3e-05 23.8 6.5 3e-05 23.8 6.5 2.6 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 AIN99267.1 - 4.3e-05 23.4 4.7 4.3e-05 23.4 4.7 2.3 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 AIN99267.1 - 0.0011 19.1 5.7 0.0011 19.1 5.7 2.3 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 AIN99267.1 - 0.0041 17.0 4.2 0.0041 17.0 4.2 2.5 3 0 0 3 3 2 1 Prokaryotic RING finger family 4 zf-RING_11 PF17123.5 AIN99267.1 - 0.56 10.0 4.2 1.5 8.6 4.2 1.8 1 0 0 1 1 1 0 RING-like zinc finger zf-ANAPC11 PF12861.7 AIN99267.1 - 2.5 8.2 5.0 1.3 9.1 0.9 2.7 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_10 PF16685.5 AIN99267.1 - 4.9 7.4 7.1 1.8 8.8 3.5 2.2 2 0 0 2 2 2 0 zinc RING finger of MSL2 Peptidase_M3 PF01432.20 AIN99268.1 - 4.4e-116 388.9 0.0 1.7e-115 386.9 0.0 1.7 2 0 0 2 2 2 1 Peptidase family M3 Peptidase_M50B PF13398.6 AIN99268.1 - 0.033 13.8 0.5 0.065 12.9 0.5 1.4 1 0 0 1 1 1 0 Peptidase M50B-like PQQ_2 PF13360.6 AIN99269.1 - 0.00033 20.3 0.3 0.00082 19.0 0.1 1.8 2 0 0 2 2 2 1 PQQ-like domain WD40 PF00400.32 AIN99270.1 - 3.6e-13 49.7 3.1 0.015 16.1 0.0 4.8 4 0 0 4 4 4 3 WD domain, G-beta repeat EF-hand_1 PF00036.32 AIN99270.1 - 5.6e-05 22.4 0.0 0.0012 18.2 0.0 2.3 2 0 0 2 2 2 1 EF hand EF-hand_7 PF13499.6 AIN99270.1 - 0.00047 20.6 0.6 0.023 15.1 0.1 2.1 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 AIN99270.1 - 0.00049 19.8 0.1 0.042 13.8 0.0 2.5 2 0 0 2 2 2 1 EF-hand domain ANAPC4_WD40 PF12894.7 AIN99270.1 - 0.00068 19.9 0.1 1.2 9.5 0.0 3.4 1 1 2 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain EF-hand_8 PF13833.6 AIN99270.1 - 0.0015 18.3 0.1 0.0061 16.4 0.1 2.1 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.6 AIN99270.1 - 0.06 12.9 0.0 0.14 11.7 0.0 1.6 1 0 0 1 1 1 0 EF hand Gmad1 PF10647.9 AIN99270.1 - 0.094 12.5 0.0 0.21 11.3 0.0 1.6 1 0 0 1 1 1 0 Lipoprotein LpqB beta-propeller domain PPK2 PF03976.14 AIN99270.1 - 0.13 11.8 0.0 0.2 11.1 0.0 1.3 1 0 0 1 1 1 0 Polyphosphate kinase 2 (PPK2) U-box PF04564.15 AIN99271.1 - 0.00059 20.0 0.0 0.0012 19.0 0.0 1.5 1 0 0 1 1 1 1 U-box domain zf-NOSIP PF15906.5 AIN99271.1 - 0.042 14.0 0.1 0.098 12.8 0.1 1.6 1 0 0 1 1 1 0 Zinc-finger of nitric oxide synthase-interacting protein Pro_dh PF01619.18 AIN99272.1 - 9.2e-64 215.8 0.4 1.6e-63 215.0 0.4 1.3 1 0 0 1 1 1 1 Proline dehydrogenase AP_endonuc_2 PF01261.24 AIN99272.1 - 0.0037 16.7 0.0 0.094 12.1 0.0 2.4 2 0 0 2 2 2 1 Xylose isomerase-like TIM barrel EF-hand_7 PF13499.6 AIN99272.1 - 0.02 15.3 0.0 0.046 14.2 0.0 1.6 1 0 0 1 1 1 0 EF-hand domain pair CTP_transf_1 PF01148.20 AIN99273.1 - 2.6e-62 211.0 18.3 3.4e-62 210.6 18.3 1.1 1 0 0 1 1 1 1 Cytidylyltransferase family Ribosomal_S28e PF01200.18 AIN99274.1 - 2e-29 101.4 0.8 2.4e-29 101.1 0.8 1.1 1 0 0 1 1 1 1 Ribosomal protein S28e Ribosomal_S28e PF01200.18 AIN99275.1 - 2e-29 101.4 0.8 2.4e-29 101.1 0.8 1.1 1 0 0 1 1 1 1 Ribosomal protein S28e MIT PF04212.18 AIN99276.1 - 3.2e-05 23.9 0.1 6.4e-05 23.0 0.1 1.5 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain FliS PF02561.14 AIN99276.1 - 0.051 13.8 0.6 0.25 11.6 0.0 2.2 2 1 0 2 2 2 0 Flagellar protein FliS Spo0A_C PF08769.11 AIN99276.1 - 0.097 12.8 0.0 0.22 11.6 0.0 1.6 1 0 0 1 1 1 0 Sporulation initiation factor Spo0A C terminal LRR_6 PF13516.6 AIN99277.1 - 9.5e-07 28.4 7.2 1.2 9.3 0.1 6.3 6 0 0 6 6 6 2 Leucine Rich repeat LRR_4 PF12799.7 AIN99277.1 - 0.038 14.4 7.7 25 5.5 1.0 5.1 3 2 2 5 5 5 0 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 AIN99277.1 - 0.049 14.2 11.7 10 7.1 0.0 5.9 6 0 0 6 6 6 0 Leucine Rich Repeat LRR_8 PF13855.6 AIN99277.1 - 3.1 7.6 9.0 5.3 6.9 0.1 4.6 5 1 0 5 5 5 0 Leucine rich repeat FA_desaturase PF00487.24 AIN99278.1 - 5.2e-21 75.6 25.0 7.5e-21 75.1 25.0 1.2 1 0 0 1 1 1 1 Fatty acid desaturase Lipid_DES PF08557.10 AIN99278.1 - 1.3e-15 56.6 0.5 2.4e-15 55.7 0.5 1.5 1 0 0 1 1 1 1 Sphingolipid Delta4-desaturase (DES) Pkinase PF00069.25 AIN99281.1 - 3e-58 197.3 0.0 5.1e-58 196.5 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 AIN99281.1 - 1.1e-35 123.2 0.0 1.8e-35 122.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 AIN99281.1 - 1.4e-06 27.8 0.0 0.00061 19.2 0.0 2.3 2 0 0 2 2 2 2 Kinase-like PAS PF00989.25 AIN99281.1 - 2.8e-06 27.3 0.0 8.8e-06 25.7 0.0 1.8 2 0 0 2 2 2 1 PAS fold Pkinase_fungal PF17667.1 AIN99281.1 - 4.5e-06 25.7 0.0 8.7e-06 24.8 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase PAS_4 PF08448.10 AIN99281.1 - 4.8e-06 26.8 0.0 2.2e-05 24.7 0.0 2.1 2 0 0 2 2 2 1 PAS fold Kdo PF06293.14 AIN99281.1 - 7.4e-05 22.2 0.0 0.00045 19.6 0.0 2.1 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family PAS_9 PF13426.7 AIN99281.1 - 0.00028 21.1 0.0 0.0012 19.0 0.0 2.1 2 0 0 2 2 2 1 PAS domain PAS_10 PF13596.6 AIN99281.1 - 0.0066 17.0 0.0 0.026 15.1 0.0 2.0 2 0 0 2 2 2 1 PAS domain PAS_8 PF13188.7 AIN99281.1 - 0.018 15.0 0.0 0.064 13.3 0.0 1.9 1 0 0 1 1 1 0 PAS domain FTA2 PF13095.6 AIN99281.1 - 0.036 13.7 0.0 0.24 11.0 0.0 2.0 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 AIN99281.1 - 0.092 12.7 0.0 0.25 11.2 0.0 1.7 2 0 0 2 2 2 0 Phosphotransferase enzyme family DUF1263 PF06882.12 AIN99282.1 - 0.043 13.9 0.2 0.13 12.3 0.2 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1263) NuA4 PF09340.10 AIN99287.1 - 4.1e-08 33.0 0.0 6.2e-06 26.0 0.0 2.4 2 0 0 2 2 2 2 Histone acetyltransferase subunit NuA4 Cnd1 PF12717.7 AIN99288.1 - 0.015 15.4 0.0 0.04 13.9 0.0 1.8 1 0 0 1 1 1 0 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 AIN99288.1 - 0.032 14.5 0.4 8.8 6.9 0.0 4.5 3 0 0 3 3 3 0 HEAT repeat UvrC_HhH_N PF08459.11 AIN99288.1 - 0.12 12.3 0.0 0.34 10.8 0.0 1.7 1 0 0 1 1 1 0 UvrC Helix-hairpin-helix N-terminal DUF5327 PF17261.2 AIN99288.1 - 2.1 9.1 6.8 4.1 8.2 2.8 3.2 2 0 0 2 2 2 0 Family of unknown function (DUF5327) DNA_binding_1 PF01035.20 AIN99289.1 - 4.1e-19 68.5 0.0 8e-19 67.6 0.0 1.5 1 0 0 1 1 1 1 6-O-methylguanine DNA methyltransferase, DNA binding domain SSI PF00720.17 AIN99289.1 - 0.028 14.4 1.2 0.06 13.3 1.2 1.5 1 0 0 1 1 1 0 Subtilisin inhibitor-like AbrB PF05145.12 AIN99289.1 - 0.036 13.0 0.7 0.053 12.5 0.7 1.2 1 0 0 1 1 1 0 Transition state regulatory protein AbrB zf-C2H2 PF00096.26 AIN99290.1 - 0.011 16.1 3.2 0.14 12.7 0.5 3.3 3 0 0 3 3 3 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 AIN99290.1 - 0.028 15.2 0.1 0.028 15.2 0.1 3.2 3 0 0 3 3 3 0 C2H2-type zinc finger zf-Di19 PF05605.12 AIN99290.1 - 0.072 13.4 0.1 0.072 13.4 0.1 2.1 2 1 1 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding PBP1_TM PF14812.6 AIN99290.1 - 4 7.9 7.1 2.6 8.5 2.6 2.5 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF789 PF05623.12 AIN99291.1 - 2.5e-09 37.2 0.0 3.2e-08 33.6 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF789) ELMO_CED12 PF04727.13 AIN99294.1 - 3.3e-41 141.3 0.0 5.9e-41 140.5 0.0 1.4 1 0 0 1 1 1 1 ELMO/CED-12 family LRR_6 PF13516.6 AIN99296.1 - 0.0022 17.9 11.9 0.28 11.3 0.1 5.6 6 0 0 6 6 6 2 Leucine Rich repeat LRR_4 PF12799.7 AIN99296.1 - 0.006 17.0 0.1 24 5.5 0.0 4.0 3 0 0 3 3 3 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 AIN99296.1 - 0.042 13.6 0.9 53 3.7 0.0 4.4 5 0 0 5 5 5 0 Leucine rich repeat DUF4460 PF14687.6 AIN99297.1 - 4.2e-08 33.2 0.1 9.4e-08 32.1 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4460) DUF4461 PF14688.6 AIN99297.1 - 0.011 15.6 4.1 0.05 13.4 1.6 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4461) DUF3741 PF12552.8 AIN99297.1 - 0.065 13.2 0.0 0.91 9.5 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3741) Sedlin_N PF04628.13 AIN99298.1 - 0.0049 17.0 0.0 0.01 16.0 0.0 1.5 1 1 0 1 1 1 1 Sedlin, N-terminal conserved region HEAT_2 PF13646.6 AIN99300.1 - 1.4e-25 89.5 9.4 8.9e-16 58.1 0.8 3.3 2 1 1 3 3 3 3 HEAT repeats HEAT_PBS PF03130.16 AIN99300.1 - 2.5e-17 61.7 13.8 0.0011 19.5 0.1 6.5 7 0 0 7 7 7 4 PBS lyase HEAT-like repeat HEAT PF02985.22 AIN99300.1 - 5.5e-07 29.3 4.7 0.017 15.3 0.1 5.3 6 1 0 6 6 6 2 HEAT repeat HEAT_EZ PF13513.6 AIN99300.1 - 0.00076 19.9 5.6 0.032 14.8 0.6 4.5 3 2 2 5 5 5 1 HEAT-like repeat DMRT-like PF15791.5 AIN99300.1 - 0.022 15.2 4.9 0.2 12.1 0.7 3.0 2 1 0 2 2 2 0 Doublesex-and mab-3-related transcription factor C1 and C2 IFRD PF05004.13 AIN99300.1 - 0.038 13.1 0.2 0.48 9.5 0.1 2.2 2 0 0 2 2 2 0 Interferon-related developmental regulator (IFRD) DUF5463 PF17551.2 AIN99300.1 - 0.16 11.9 0.2 0.32 11.0 0.2 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5463) TRAM_LAG1_CLN8 PF03798.16 AIN99301.1 - 1.5e-16 60.8 15.8 1.5e-16 60.8 15.8 1.5 2 0 0 2 2 2 1 TLC domain Cas1_AcylT PF07779.12 AIN99301.1 - 0.003 16.5 5.2 0.0054 15.7 4.4 1.8 1 1 0 1 1 1 1 10 TM Acyl Transferase domain found in Cas1p 4HBT_2 PF13279.6 AIN99302.1 - 1.8e-10 41.3 0.0 2.8e-10 40.8 0.0 1.4 1 0 0 1 1 1 1 Thioesterase-like superfamily 4HBT PF03061.22 AIN99302.1 - 5.9e-09 36.2 0.0 7.9e-08 32.6 0.0 2.4 2 0 0 2 2 2 1 Thioesterase superfamily Acyl-ACP_TE PF01643.17 AIN99302.1 - 0.029 13.7 0.9 0.3 10.4 1.0 2.0 1 1 0 1 1 1 0 Acyl-ACP thioesterase MarR_2 PF12802.7 AIN99303.1 - 0.016 15.1 0.0 45 4.0 0.0 4.6 5 0 0 5 5 5 0 MarR family MT PF12777.7 AIN99303.1 - 0.025 13.6 0.0 0.048 12.7 0.0 1.4 1 0 0 1 1 1 0 Microtubule-binding stalk of dynein motor DUF1413 PF07205.11 AIN99303.1 - 0.044 13.8 0.0 1.2e+02 2.8 0.0 4.3 4 0 0 4 4 4 0 Domain of unknown function (DUF1413) NdhS PF11623.8 AIN99303.1 - 5.9 6.6 6.2 50 3.7 0.0 5.7 8 0 0 8 8 8 0 NAD(P)H dehydrogenase subunit S ABC_tran_Xtn PF12848.7 AIN99304.1 - 0.042 13.9 6.8 0.14 12.2 6.8 1.8 1 0 0 1 1 1 0 ABC transporter SCO1-SenC PF02630.14 AIN99305.1 - 3.8e-44 149.8 0.0 5.6e-44 149.3 0.0 1.3 1 0 0 1 1 1 1 SCO1/SenC AhpC-TSA PF00578.21 AIN99305.1 - 0.00068 19.6 0.0 0.0013 18.7 0.0 1.6 1 1 0 1 1 1 1 AhpC/TSA family Thioredoxin_8 PF13905.6 AIN99305.1 - 0.0045 17.3 0.0 0.009 16.3 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin-like Methyltransf_23 PF13489.6 AIN99308.1 - 3.9e-14 52.8 0.0 6.2e-14 52.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 AIN99308.1 - 8.4e-13 48.4 0.0 8.6e-06 25.6 0.0 2.4 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_11 PF08241.12 AIN99308.1 - 2.9e-10 40.7 0.0 0.0011 19.5 0.0 2.5 1 1 0 2 2 2 2 Methyltransferase domain Methyltransf_12 PF08242.12 AIN99308.1 - 1.2e-09 38.8 0.0 1.4e-08 35.3 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 AIN99308.1 - 1.8e-09 38.2 0.1 2.3e-05 25.0 0.0 3.0 1 1 1 2 2 2 2 Methyltransferase domain DREV PF05219.12 AIN99308.1 - 0.0016 17.6 0.0 0.0055 15.8 0.0 1.7 1 1 0 2 2 2 1 DREV methyltransferase CMAS PF02353.20 AIN99308.1 - 0.0099 15.2 0.1 0.037 13.3 0.0 1.8 1 1 1 2 2 2 1 Mycolic acid cyclopropane synthetase Methyltransf_3 PF01596.17 AIN99308.1 - 0.091 11.9 0.0 0.16 11.1 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase PHD PF00628.29 AIN99309.1 - 0.0032 17.3 6.8 0.0063 16.4 6.8 1.5 1 0 0 1 1 1 1 PHD-finger Zn_ribbon_17 PF17120.5 AIN99309.1 - 0.06 13.0 3.9 0.13 12.0 3.9 1.5 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type SBE2 PF17076.5 AIN99309.1 - 0.12 10.6 7.6 0.17 10.1 7.6 1.2 1 0 0 1 1 1 0 SBE2, cell-wall formation ATG22 PF11700.8 AIN99311.1 - 0.011 14.5 0.0 0.018 13.7 0.0 1.3 1 0 0 1 1 1 0 Vacuole effluxer Atg22 like HEAT PF02985.22 AIN99311.1 - 0.18 12.2 3.4 0.54 10.7 0.0 3.4 3 0 0 3 3 3 0 HEAT repeat PQ-loop PF04193.14 AIN99312.1 - 6.3e-19 67.5 0.2 1.7e-12 46.9 0.0 2.6 2 0 0 2 2 2 2 PQ loop repeat ER_lumen_recept PF00810.18 AIN99312.1 - 0.015 16.1 1.9 0.015 16.1 1.9 2.3 2 0 0 2 2 2 0 ER lumen protein retaining receptor UL42 PF17638.2 AIN99312.1 - 0.15 12.0 0.1 0.15 12.0 0.1 2.4 3 0 0 3 3 3 0 HCMV UL42 Pkinase PF00069.25 AIN99314.1 - 7.2e-13 48.5 0.0 1.8e-09 37.4 0.0 2.9 3 1 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 AIN99314.1 - 3.6e-07 29.7 0.4 0.0023 17.2 0.0 3.0 3 0 0 3 3 3 2 Protein tyrosine kinase Peptidase_C48 PF02902.19 AIN99315.1 - 6.1e-15 55.6 0.0 3.2e-06 27.2 0.0 2.9 2 1 0 2 2 2 2 Ulp1 protease family, C-terminal catalytic domain DUF4050 PF13259.6 AIN99316.1 - 0.17 12.2 2.0 0.59 10.4 0.0 2.6 2 2 0 2 2 2 0 Protein of unknown function (DUF4050) Metallophos PF00149.28 AIN99318.1 - 4.5e-15 56.7 0.0 8.9e-13 49.2 0.0 3.3 3 1 0 3 3 3 1 Calcineurin-like phosphoesterase PRIMA1 PF16101.5 AIN99318.1 - 0.072 13.1 0.2 0.2 11.7 0.2 1.7 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 Pkinase PF00069.25 AIN99319.1 - 1.8e-32 112.8 0.0 1.3e-15 57.4 0.0 3.6 4 0 0 4 4 4 2 Protein kinase domain Pkinase_Tyr PF07714.17 AIN99319.1 - 6.3e-06 25.7 0.0 0.00024 20.5 0.0 2.9 4 0 0 4 4 4 1 Protein tyrosine kinase Haspin_kinase PF12330.8 AIN99319.1 - 0.0011 18.0 0.0 0.0017 17.4 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Pkinase_fungal PF17667.1 AIN99319.1 - 0.059 12.1 0.3 0.25 10.1 0.0 1.9 2 0 0 2 2 2 0 Fungal protein kinase TFIIA PF03153.13 AIN99319.1 - 0.93 9.4 7.1 4.3 7.2 7.1 2.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Pkinase PF00069.25 AIN99320.1 - 6.6e-08 32.2 0.0 5.4e-06 26.0 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Limkain-b1 PF11608.8 AIN99321.1 - 0.084 13.0 0.1 0.26 11.4 0.1 1.8 1 1 0 1 1 1 0 Limkain b1 Pet191_N PF10203.9 AIN99322.1 - 0.012 15.9 4.2 0.17 12.2 0.6 2.2 1 1 1 2 2 2 0 Cytochrome c oxidase assembly protein PET191 CHCH PF06747.13 AIN99322.1 - 0.07 13.3 2.3 0.07 13.3 2.3 2.2 3 0 0 3 3 3 0 CHCH domain FtsJ PF01728.19 AIN99323.1 - 6.2e-05 23.2 0.0 0.00034 20.8 0.0 2.1 1 1 0 1 1 1 1 FtsJ-like methyltransferase Arf PF00025.21 AIN99328.1 - 1.2e-22 80.2 0.3 3.4e-09 36.4 0.0 4.4 3 1 1 4 4 4 3 ADP-ribosylation factor family G-alpha PF00503.20 AIN99328.1 - 2.3e-10 40.2 0.0 2.3e-05 23.7 0.0 2.1 2 0 0 2 2 2 2 G-protein alpha subunit AAA_29 PF13555.6 AIN99328.1 - 0.0001 21.9 0.0 0.0011 18.7 0.0 2.2 2 0 0 2 2 2 1 P-loop containing region of AAA domain Roc PF08477.13 AIN99328.1 - 0.00018 21.7 0.0 0.66 10.2 0.0 2.7 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 AIN99328.1 - 0.00022 20.7 0.0 0.2 11.1 0.0 2.4 2 1 0 2 2 2 2 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.27 AIN99328.1 - 0.00023 20.7 0.0 0.27 10.8 0.0 2.3 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 AIN99328.1 - 0.00095 19.2 0.0 0.045 13.8 0.0 2.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase ABC_tran PF00005.27 AIN99328.1 - 0.0027 18.2 0.0 0.01 16.4 0.0 2.0 2 0 0 2 2 2 1 ABC transporter Ras PF00071.22 AIN99328.1 - 0.0057 16.3 0.0 6.3 6.4 0.0 3.7 2 1 0 2 2 2 1 Ras family Dynamin_N PF00350.23 AIN99328.1 - 0.0059 16.7 0.5 0.014 15.5 0.5 1.8 1 1 0 1 1 1 1 Dynamin family AAA_28 PF13521.6 AIN99328.1 - 0.016 15.5 0.0 0.036 14.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 AIN99328.1 - 0.017 15.5 2.2 0.054 13.9 2.2 2.0 1 1 0 1 1 1 0 AAA ATPase domain Septin PF00735.18 AIN99328.1 - 0.077 12.3 0.0 0.16 11.3 0.0 1.5 1 0 0 1 1 1 0 Septin TniB PF05621.11 AIN99328.1 - 0.1 12.0 0.1 0.25 10.7 0.0 1.7 2 0 0 2 2 2 0 Bacterial TniB protein AAA_23 PF13476.6 AIN99328.1 - 0.16 12.5 0.0 0.31 11.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 AIN99330.1 - 2.2e-06 28.2 1.4 3.3e-05 24.3 0.2 3.0 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 AIN99330.1 - 0.0002 21.6 0.1 0.98 9.7 0.1 2.7 2 0 0 2 2 2 2 AAA domain Kinesin PF00225.23 AIN99330.1 - 0.021 13.8 0.0 0.042 12.8 0.0 1.4 1 0 0 1 1 1 0 Kinesin motor domain CoaE PF01121.20 AIN99330.1 - 0.047 13.4 0.0 0.16 11.6 0.0 1.9 2 0 0 2 2 2 0 Dephospho-CoA kinase AAA_19 PF13245.6 AIN99330.1 - 0.085 13.2 0.1 0.52 10.6 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 AIN99330.1 - 0.14 11.6 0.0 0.29 10.6 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region Microtub_bd PF16796.5 AIN99330.1 - 0.23 11.4 0.0 0.47 10.4 0.0 1.4 1 0 0 1 1 1 0 Microtubule binding Ribosomal_L38e PF01781.18 AIN99331.1 - 6.4e-29 99.9 4.3 7.6e-29 99.6 4.3 1.1 1 0 0 1 1 1 1 Ribosomal L38e protein family GDP_Man_Dehyd PF16363.5 AIN99332.1 - 1.9e-65 221.4 0.1 5.5e-60 203.5 0.0 2.0 1 1 1 2 2 2 2 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 AIN99332.1 - 2.3e-51 174.6 0.2 5.4e-51 173.4 0.2 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 AIN99332.1 - 7.6e-23 81.0 0.1 2e-19 69.8 0.0 2.1 2 0 0 2 2 2 2 Male sterility protein 3Beta_HSD PF01073.19 AIN99332.1 - 1.9e-19 69.8 0.0 8e-14 51.3 0.0 2.1 2 0 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 AIN99332.1 - 3.9e-19 68.9 0.0 6.2e-13 48.5 0.0 3.0 2 1 0 2 2 2 2 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 AIN99332.1 - 1.1e-18 67.3 0.5 1e-17 64.1 0.4 2.0 2 0 0 2 2 2 1 RmlD substrate binding domain Aminotran_5 PF00266.19 AIN99333.1 - 1.5e-13 50.5 0.0 2.2e-13 49.9 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.20 AIN99333.1 - 0.00065 18.3 0.0 0.00097 17.8 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.17 AIN99333.1 - 0.019 14.3 0.2 0.049 12.9 0.0 1.7 2 0 0 2 2 2 0 DegT/DnrJ/EryC1/StrS aminotransferase family Sec1 PF00995.23 AIN99335.1 - 1.8e-86 291.7 0.0 2.1e-86 291.4 0.0 1.0 1 0 0 1 1 1 1 Sec1 family MRP-S34 PF16053.5 AIN99336.1 - 1.8e-05 24.4 0.0 2.8e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial 28S ribosomal protein S34 CN_hydrolase PF00795.22 AIN99337.1 - 1.4e-49 168.8 0.0 1.6e-49 168.6 0.0 1.0 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Esterase PF00756.20 AIN99338.1 - 0.12 12.0 0.0 0.23 11.1 0.0 1.5 1 0 0 1 1 1 0 Putative esterase Lipase PF00151.19 AIN99338.1 - 0.14 11.4 0.0 0.19 11.0 0.0 1.2 1 0 0 1 1 1 0 Lipase AMH_N PF04709.12 AIN99340.1 - 0.0016 17.4 0.3 0.0017 17.4 0.3 1.1 1 0 0 1 1 1 1 Anti-Mullerian hormone, N terminal region WD40 PF00400.32 AIN99342.1 - 3.7e-08 33.9 11.6 0.044 14.7 1.1 5.2 6 0 0 6 6 6 3 WD domain, G-beta repeat Zip PF02535.22 AIN99342.1 - 0.0093 15.2 1.3 0.018 14.3 1.3 1.4 1 0 0 1 1 1 1 ZIP Zinc transporter DUF4533 PF15047.6 AIN99342.1 - 0.016 14.7 1.1 0.016 14.7 1.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF4533) NOA36 PF06524.12 AIN99342.1 - 0.23 10.8 11.2 0.37 10.1 11.2 1.3 1 0 0 1 1 1 0 NOA36 protein GEMIN8 PF15348.6 AIN99342.1 - 0.56 10.5 17.7 0.072 13.4 13.2 1.7 2 0 0 2 2 2 0 Gemini of Cajal bodies-associated protein 8 RNA_pol_3_Rpc31 PF11705.8 AIN99342.1 - 1.8 8.8 20.8 5.1 7.3 20.8 1.8 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 MutS_III PF05192.18 AIN99342.1 - 2.2 8.4 5.5 4.4 7.5 5.5 1.4 1 0 0 1 1 1 0 MutS domain III ALMT PF11744.8 AIN99342.1 - 2.7 6.7 10.4 5.2 5.8 10.4 1.4 1 0 0 1 1 1 0 Aluminium activated malate transporter Ribosomal_L29 PF00831.23 AIN99343.1 - 3.3e-18 65.4 2.6 3.3e-18 65.4 2.6 2.2 2 1 0 2 2 2 1 Ribosomal L29 protein MRP-L47 PF06984.13 AIN99343.1 - 0.25 11.5 3.1 0.12 12.5 0.6 1.9 2 1 0 2 2 2 0 Mitochondrial 39-S ribosomal protein L47 (MRP-L47) DUF724 PF05266.14 AIN99343.1 - 0.27 11.1 6.2 0.39 10.5 6.2 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF724) CCDC-167 PF15188.6 AIN99343.1 - 9.3 6.7 12.2 14 6.1 0.8 2.2 1 1 1 2 2 2 0 Coiled-coil domain-containing protein 167 Ribosomal_L29 PF00831.23 AIN99344.1 - 3.3e-18 65.4 2.6 3.3e-18 65.4 2.6 2.2 2 1 0 2 2 2 1 Ribosomal L29 protein MRP-L47 PF06984.13 AIN99344.1 - 0.25 11.5 3.1 0.12 12.5 0.6 1.9 2 1 0 2 2 2 0 Mitochondrial 39-S ribosomal protein L47 (MRP-L47) DUF724 PF05266.14 AIN99344.1 - 0.27 11.1 6.2 0.39 10.5 6.2 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF724) CCDC-167 PF15188.6 AIN99344.1 - 9.3 6.7 12.2 14 6.1 0.8 2.2 1 1 1 2 2 2 0 Coiled-coil domain-containing protein 167 Sec1 PF00995.23 AIN99346.1 - 7.4e-89 299.5 0.0 8.5e-89 299.3 0.0 1.0 1 0 0 1 1 1 1 Sec1 family HECT PF00632.25 AIN99347.1 - 1.1e-34 120.4 0.0 1.9e-34 119.5 0.0 1.4 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) SPRY PF00622.28 AIN99347.1 - 1.2e-12 48.0 0.0 1.2e-09 38.3 0.0 2.9 3 0 0 3 3 3 2 SPRY domain zf-RanBP PF00641.18 AIN99347.1 - 1.2e-06 27.7 15.0 4.3e-05 22.7 2.7 2.8 1 1 1 2 2 2 2 Zn-finger in Ran binding protein and others HEAT PF02985.22 AIN99347.1 - 0.29 11.5 3.0 25 5.5 0.7 3.6 2 0 0 2 2 2 0 HEAT repeat fn3 PF00041.21 AIN99348.1 - 2e-88 290.8 56.3 9.8e-05 22.6 0.3 37.9 41 3 0 41 41 41 21 Fibronectin type III domain Pur_ac_phosph_N PF16656.5 AIN99348.1 - 1.5e-39 134.5 49.5 0.0034 17.9 1.3 27.4 29 0 0 29 29 29 11 Purple acid Phosphatase, N-terminal domain Interfer-bind PF09294.10 AIN99348.1 - 1.1e-17 64.3 0.7 1.9 8.8 0.0 14.8 16 0 0 16 16 16 3 Interferon-alpha/beta receptor, fibronectin type III Glyco_hydro_36C PF16874.5 AIN99348.1 - 7.7e-06 26.3 0.0 19 5.8 0.0 9.4 13 0 0 13 13 13 1 Glycosyl hydrolase family 36 C-terminal domain Arylsulfotran_N PF17425.2 AIN99348.1 - 0.00073 19.5 0.0 1.2 9.2 0.0 6.0 7 0 0 7 7 7 1 Arylsulfotransferase Ig-like domain DUF2369 PF10179.9 AIN99348.1 - 0.0019 18.5 0.2 38 4.8 0.0 6.3 5 0 0 5 5 5 0 Uncharacterised conserved protein (DUF2369) fn3_4 PF16794.5 AIN99348.1 - 0.068 13.1 0.0 9.2 6.2 0.0 4.5 4 0 0 4 4 4 0 Fibronectin-III type domain zf-primase PF09329.11 AIN99349.1 - 1.7e-09 37.3 0.3 3.6e-09 36.3 0.3 1.6 1 0 0 1 1 1 1 Primase zinc finger Mcm10 PF09332.11 AIN99349.1 - 7.3e-09 35.5 4.9 1.5e-08 34.5 4.9 1.4 1 0 0 1 1 1 1 Mcm10 replication factor HypA PF01155.19 AIN99349.1 - 0.26 11.3 1.1 0.83 9.7 1.1 1.9 1 1 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Tim17 PF02466.19 AIN99350.1 - 3.1e-10 40.4 1.7 1.7e-09 38.1 0.8 2.0 2 0 0 2 2 2 1 Tim17/Tim22/Tim23/Pmp24 family SOAR PF16533.5 AIN99351.1 - 0.00033 20.6 3.9 0.0091 15.9 0.5 2.9 2 0 0 2 2 2 2 STIM1 Orai1-activating region USP8_interact PF08941.10 AIN99351.1 - 0.032 14.1 2.3 0.051 13.4 0.3 2.2 2 0 0 2 2 2 0 USP8 interacting BTB PF00651.31 AIN99352.1 - 1.9e-12 47.4 0.1 4.4e-05 23.7 0.0 2.9 2 1 0 2 2 2 2 BTB/POZ domain MATH PF00917.26 AIN99352.1 - 0.00032 20.8 0.0 0.00057 20.0 0.0 1.4 1 0 0 1 1 1 1 MATH domain JAB PF01398.21 AIN99353.1 - 6.6e-16 58.3 0.4 2.7e-09 37.0 0.1 2.4 2 0 0 2 2 2 2 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Prok-JAB PF14464.6 AIN99353.1 - 7.4e-09 35.4 1.0 6.6e-06 25.9 0.3 2.6 2 0 0 2 2 2 2 Prokaryotic homologs of the JAB domain Pkinase PF00069.25 AIN99354.1 - 1.4e-38 132.8 0.0 1.8e-38 132.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 AIN99354.1 - 1.7e-25 89.8 0.0 2.5e-25 89.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 AIN99354.1 - 0.00071 19.0 0.3 0.0014 18.1 0.3 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 AIN99354.1 - 0.0043 16.4 0.0 0.012 15.0 0.0 1.6 1 1 0 1 1 1 1 Kinase-like Tankyrase_bdg_C PF15327.6 AIN99354.1 - 1.7 9.1 7.0 0.16 12.4 1.2 2.2 2 0 0 2 2 2 0 Tankyrase binding protein C terminal domain UPF0492 PF15744.5 AIN99355.1 - 0.0073 15.6 3.2 0.0096 15.2 3.2 1.1 1 0 0 1 1 1 1 Uncharacterized protein family UPF0492 DUF2513 PF10711.9 AIN99355.1 - 0.11 12.7 0.1 0.37 11.1 0.0 1.9 2 0 0 2 2 2 0 Hypothetical protein (DUF2513) TackOD1 PF18551.1 AIN99357.1 - 0.0025 17.5 6.1 0.13 12.0 1.0 2.1 1 1 1 2 2 2 2 Thaumarchaeal output domain 1 Stc1 PF12898.7 AIN99357.1 - 0.082 13.5 8.4 0.26 11.9 0.2 2.9 1 1 2 3 3 3 0 Stc1 domain RNHCP PF12647.7 AIN99357.1 - 0.11 12.4 3.4 0.22 11.5 1.6 2.1 2 1 0 2 2 2 0 RNHCP domain ArfGap PF01412.18 AIN99357.1 - 0.5 10.5 5.1 1.8 8.6 3.8 2.0 1 1 1 2 2 2 0 Putative GTPase activating protein for Arf CDP-OH_P_transf PF01066.21 AIN99358.1 - 4.1e-13 49.9 1.8 4.1e-13 49.9 1.8 2.7 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase JIP_LZII PF16471.5 AIN99359.1 - 0.12 12.5 0.1 0.12 12.5 0.1 15.7 16 2 3 19 19 19 0 JNK-interacting protein leucine zipper II APG6_N PF17675.1 AIN99359.1 - 0.12 12.9 0.1 0.12 12.9 0.1 15.5 7 3 4 12 12 12 0 Apg6 coiled-coil region HU-CCDC81_bac_2 PF18175.1 AIN99359.1 - 0.17 11.8 0.7 2.2 8.2 0.1 3.5 2 0 0 2 2 2 0 CCDC81-like prokaryotic HU domain 2 CHCH PF06747.13 AIN99360.1 - 8.1e-06 25.8 11.0 0.0014 18.7 5.6 2.4 2 0 0 2 2 2 2 CHCH domain MTCP1 PF08991.10 AIN99360.1 - 0.00041 20.5 4.9 0.01 16.1 0.9 2.3 2 0 0 2 2 2 2 Mature-T-Cell Proliferation I type CX9C PF16860.5 AIN99360.1 - 0.0035 17.3 3.5 0.0035 17.3 3.5 2.3 3 0 0 3 3 3 1 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, Ecm29 PF13001.7 AIN99360.1 - 0.087 11.5 0.0 0.093 11.4 0.0 1.0 1 0 0 1 1 1 0 Proteasome stabiliser Cmc1 PF08583.10 AIN99360.1 - 2 8.5 13.6 18 5.4 5.8 3.4 2 2 1 3 3 3 0 Cytochrome c oxidase biogenesis protein Cmc1 like NDUF_B7 PF05676.13 AIN99360.1 - 5 6.9 10.5 1.2 8.9 1.7 2.7 2 1 1 3 3 3 0 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) COX6B PF02297.17 AIN99360.1 - 6.1 7.1 11.0 1.9 8.8 7.0 2.2 2 1 0 2 2 2 0 Cytochrome oxidase c subunit VIb Pkinase PF00069.25 AIN99361.1 - 7.7e-47 159.9 0.0 9.4e-47 159.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 AIN99361.1 - 2.4e-28 99.1 0.0 3.4e-28 98.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 AIN99361.1 - 0.00066 18.6 0.0 0.001 17.9 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 AIN99361.1 - 0.0016 18.4 0.0 0.0056 16.6 0.0 1.9 2 1 1 3 3 3 1 Phosphotransferase enzyme family Kinase-like PF14531.6 AIN99361.1 - 0.014 14.8 0.0 0.02 14.2 0.0 1.3 1 0 0 1 1 1 0 Kinase-like RIO1 PF01163.22 AIN99361.1 - 0.022 14.4 0.0 0.032 13.8 0.0 1.2 1 0 0 1 1 1 0 RIO1 family DnaJ PF00226.31 AIN99362.1 - 1.1e-06 28.6 0.0 2.6e-06 27.5 0.0 1.6 1 0 0 1 1 1 1 DnaJ domain RNF220 PF15926.5 AIN99362.1 - 0.087 12.4 0.2 0.087 12.4 0.2 3.0 3 1 0 3 3 3 0 E3 ubiquitin-protein ligase RNF220 SRP-alpha_N PF04086.13 AIN99362.1 - 6.5 6.6 22.1 6.6 6.6 5.9 2.2 2 0 0 2 2 2 0 Signal recognition particle, alpha subunit, N-terminal Metallophos PF00149.28 AIN99363.1 - 1.3e-33 117.2 0.0 2.1e-33 116.6 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase SET PF00856.28 AIN99365.1 - 2.9e-13 50.6 0.0 2.9e-11 44.1 0.0 2.4 1 1 0 1 1 1 1 SET domain Dala_Dala_lig_C PF07478.13 AIN99365.1 - 2.8e-12 46.6 0.0 4.6e-12 45.9 0.0 1.2 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 AIN99365.1 - 0.00034 20.2 0.0 0.00053 19.6 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_3 PF02655.14 AIN99365.1 - 0.025 14.6 0.0 0.047 13.8 0.0 1.4 1 0 0 1 1 1 0 ATP-grasp domain ATP-grasp_4 PF13535.6 AIN99365.1 - 0.085 12.5 0.1 0.41 10.2 0.1 2.1 2 1 0 2 2 2 0 ATP-grasp domain GARS_A PF01071.19 AIN99365.1 - 0.097 12.4 0.0 0.15 11.8 0.0 1.3 1 0 0 1 1 1 0 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain Pkinase PF00069.25 AIN99366.1 - 1.5e-44 152.3 0.0 2.4e-44 151.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 AIN99366.1 - 2.5e-33 115.4 0.0 3.1e-33 115.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 AIN99366.1 - 0.0015 17.4 0.0 0.0022 16.9 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase TrmO_C PF18389.1 AIN99366.1 - 0.049 13.7 0.0 0.1 12.7 0.0 1.5 1 0 0 1 1 1 0 TrmO C-terminal domain SMP PF04927.12 AIN99367.1 - 0.031 14.8 1.6 0.063 13.8 1.1 1.7 1 1 0 1 1 1 0 Seed maturation protein TIR-like PF10137.9 AIN99367.1 - 0.12 12.3 0.1 0.17 11.8 0.1 1.3 1 1 0 1 1 1 0 Predicted nucleotide-binding protein containing TIR-like domain PqiA PF04403.13 AIN99368.1 - 2.5e-13 50.2 23.7 1.8e-11 44.1 8.7 3.5 2 1 1 3 3 3 3 Paraquat-inducible protein A LapA_dom PF06305.11 AIN99368.1 - 0.0085 15.9 3.3 0.079 12.8 0.0 3.3 3 0 0 3 3 3 1 Lipopolysaccharide assembly protein A domain FAD_binding_3 PF01494.19 AIN99370.1 - 1.1e-08 34.8 0.0 1.2e-06 28.0 0.0 3.0 2 1 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.6 AIN99370.1 - 6.3e-07 29.5 0.1 2.3e-06 27.7 0.0 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 AIN99370.1 - 0.00032 19.9 0.1 0.00079 18.6 0.1 1.6 2 0 0 2 2 2 1 FAD binding domain Pyr_redox PF00070.27 AIN99370.1 - 0.00057 20.4 0.0 0.0013 19.3 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 AIN99370.1 - 0.0008 18.7 0.0 0.0031 16.8 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 AIN99370.1 - 0.0014 18.2 0.2 0.004 16.8 0.0 1.8 2 1 1 3 3 3 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 AIN99370.1 - 0.0048 16.0 0.1 0.037 13.1 0.0 2.3 3 0 0 3 3 3 1 Lycopene cyclase protein Thi4 PF01946.17 AIN99370.1 - 0.07 12.4 0.0 0.11 11.7 0.0 1.3 1 0 0 1 1 1 0 Thi4 family Pyr_redox_3 PF13738.6 AIN99370.1 - 0.098 11.9 0.0 0.16 11.2 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase zf-CSL PF05207.13 AIN99372.1 - 5.7e-15 54.8 0.1 8.4e-15 54.3 0.1 1.2 1 0 0 1 1 1 1 CSL zinc finger CLZ PF16526.5 AIN99373.1 - 0.038 14.3 0.7 0.094 13.1 0.7 1.7 1 0 0 1 1 1 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Bacillus_HBL PF05791.11 AIN99373.1 - 0.095 12.5 1.1 0.17 11.7 1.1 1.3 1 0 0 1 1 1 0 Bacillus haemolytic enterotoxin (HBL) Uso1_p115_C PF04871.13 AIN99373.1 - 0.18 12.2 3.0 0.48 10.8 3.0 1.6 1 0 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region HECT PF00632.25 AIN99374.1 - 4.4e-07 29.7 0.0 0.00014 21.5 0.0 2.6 3 0 0 3 3 3 2 HECT-domain (ubiquitin-transferase) RTT107_BRCT_5 PF16770.5 AIN99375.1 - 0.021 14.7 0.0 0.1 12.5 0.0 2.3 2 0 0 2 2 2 0 Regulator of Ty1 transposition protein 107 BRCT domain DUF3606 PF12244.8 AIN99375.1 - 0.21 11.5 4.4 0.094 12.7 0.9 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3606) DUF3584 PF12128.8 AIN99375.1 - 0.34 8.4 90.6 0.53 7.7 36.2 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) Spectrin_like PF18373.1 AIN99375.1 - 0.61 10.2 8.0 0.072 13.2 0.5 3.3 3 0 0 3 3 3 0 Spectrin like domain DUF812 PF05667.11 AIN99375.1 - 5.4 5.8 73.1 0.012 14.6 36.7 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF812) PKcGMP_CC PF16808.5 AIN99375.1 - 7.8 6.4 14.2 0.42 10.5 1.4 4.6 4 0 0 4 4 4 0 Coiled-coil N-terminus of cGMP-dependent protein kinase ABC_membrane PF00664.23 AIN99376.1 - 4.3e-97 325.1 25.6 4e-53 180.8 9.6 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 AIN99376.1 - 2.3e-69 232.2 0.0 9e-35 120.2 0.0 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 AIN99376.1 - 1.9e-12 47.1 0.1 5.3e-06 26.0 0.0 3.6 2 2 1 3 3 3 2 RecF/RecN/SMC N terminal domain Zeta_toxin PF06414.12 AIN99376.1 - 4.4e-06 26.1 0.1 0.0044 16.3 0.0 2.7 2 0 0 2 2 2 2 Zeta toxin AAA_29 PF13555.6 AIN99376.1 - 6.3e-06 25.8 0.2 0.06 13.1 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 AIN99376.1 - 1.3e-05 25.2 0.0 0.11 12.5 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA_16 PF13191.6 AIN99376.1 - 2.1e-05 25.0 0.1 0.28 11.5 0.0 2.7 2 0 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.6 AIN99376.1 - 5.7e-05 23.4 1.2 0.23 11.7 0.1 3.7 2 2 0 2 2 2 1 AAA domain ABC_ATPase PF09818.9 AIN99376.1 - 6.3e-05 22.0 0.1 0.0016 17.4 0.1 2.4 2 0 0 2 2 2 1 Predicted ATPase of the ABC class AAA PF00004.29 AIN99376.1 - 0.00013 22.4 0.8 1 9.8 0.1 3.9 2 2 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_23 PF13476.6 AIN99376.1 - 0.00028 21.5 0.7 0.45 11.0 0.1 2.4 2 0 0 2 2 2 2 AAA domain AAA_15 PF13175.6 AIN99376.1 - 0.00038 20.3 0.0 0.29 10.8 0.0 2.2 2 0 0 2 2 2 2 AAA ATPase domain Rad17 PF03215.15 AIN99376.1 - 0.00042 20.3 0.0 0.44 10.4 0.0 3.2 3 0 0 3 3 3 1 Rad17 P-loop domain ATP-synt_ab PF00006.25 AIN99376.1 - 0.00047 19.9 0.0 0.23 11.1 0.0 2.7 2 1 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain AAA_5 PF07728.14 AIN99376.1 - 0.00061 19.8 0.0 0.5 10.4 0.0 3.7 4 0 0 4 4 3 1 AAA domain (dynein-related subfamily) RNA_helicase PF00910.22 AIN99376.1 - 0.0017 18.7 0.3 3.8 8.0 0.0 3.2 3 0 0 3 3 2 1 RNA helicase G-alpha PF00503.20 AIN99376.1 - 0.0026 17.0 0.0 0.34 10.0 0.0 2.2 2 0 0 2 2 2 1 G-protein alpha subunit DUF87 PF01935.17 AIN99376.1 - 0.0044 17.1 0.4 2.1 8.4 0.1 2.5 2 0 0 2 2 2 1 Helicase HerA, central domain AAA_7 PF12775.7 AIN99376.1 - 0.005 16.4 0.1 1.7 8.2 0.0 2.5 2 0 0 2 2 2 1 P-loop containing dynein motor region Viral_helicase1 PF01443.18 AIN99376.1 - 0.0074 16.1 0.2 7.2 6.3 0.0 3.3 4 0 0 4 4 3 0 Viral (Superfamily 1) RNA helicase AAA_14 PF13173.6 AIN99376.1 - 0.0077 16.3 0.0 2.4 8.2 0.0 3.1 2 0 0 2 2 2 1 AAA domain SbcCD_C PF13558.6 AIN99376.1 - 0.016 15.5 6.0 8.9 6.6 0.5 4.3 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_28 PF13521.6 AIN99376.1 - 0.024 14.9 0.0 2.3 8.4 0.0 2.6 2 0 0 2 2 2 0 AAA domain MoaE PF02391.17 AIN99376.1 - 0.034 14.4 0.6 4.8 7.5 0.0 3.6 4 0 0 4 4 3 0 MoaE protein NTPase_1 PF03266.15 AIN99376.1 - 0.045 13.7 0.4 30 4.5 0.0 3.3 3 0 0 3 3 3 0 NTPase MMR_HSR1 PF01926.23 AIN99376.1 - 0.05 13.7 0.9 9.2 6.4 0.0 3.3 3 0 0 3 3 3 0 50S ribosome-binding GTPase DUF815 PF05673.13 AIN99376.1 - 0.065 12.4 0.0 11 5.1 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_18 PF13238.6 AIN99376.1 - 0.065 13.8 0.0 13 6.3 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.6 AIN99376.1 - 0.065 12.8 1.8 8.6 5.9 0.0 3.3 4 0 0 4 4 4 0 AAA domain NB-ARC PF00931.22 AIN99376.1 - 0.067 12.4 0.1 4.9 6.3 0.0 2.5 2 0 0 2 2 2 0 NB-ARC domain AAA_21 PF13304.6 AIN99376.1 - 0.072 12.9 0.1 4.5 7.0 0.0 2.8 3 0 0 3 3 2 0 AAA domain, putative AbiEii toxin, Type IV TA system TsaE PF02367.17 AIN99376.1 - 0.17 11.9 0.1 32 4.6 0.0 2.5 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE DEAD PF00270.29 AIN99376.1 - 0.98 9.2 2.7 6.6 6.5 0.3 3.2 2 2 0 2 2 2 0 DEAD/DEAH box helicase CPBP PF02517.16 AIN99378.1 - 9.7e-20 70.7 0.2 9.7e-20 70.7 0.2 2.2 3 1 0 3 3 3 1 CPBP intramembrane metalloprotease Glucosamine_iso PF01182.20 AIN99379.1 - 3.9e-52 177.4 0.0 4.4e-52 177.2 0.0 1.0 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase CdiI_4 PF18624.1 AIN99379.1 - 0.12 12.9 0.0 0.2 12.2 0.0 1.3 1 0 0 1 1 1 0 CDI immunity protein AA_kinase PF00696.28 AIN99380.1 - 9.8e-42 143.2 0.1 1.2e-41 142.9 0.1 1.0 1 0 0 1 1 1 1 Amino acid kinase family TPR_20 PF14561.6 AIN99382.1 - 9.7e-05 22.6 1.1 0.011 16.1 0.0 3.7 3 2 1 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.17 AIN99382.1 - 0.00079 19.4 3.0 1 9.6 0.0 3.8 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_6 PF13174.6 AIN99382.1 - 0.014 16.0 3.4 1.7 9.4 0.1 4.4 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.6 AIN99382.1 - 0.024 15.4 6.0 1.7 9.6 0.0 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_19 PF14559.6 AIN99382.1 - 0.056 13.9 5.3 2.3 8.8 0.1 4.2 3 2 2 5 5 5 0 Tetratricopeptide repeat TPR_12 PF13424.6 AIN99382.1 - 0.068 13.5 0.7 20 5.6 0.1 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_16 PF13432.6 AIN99382.1 - 0.099 13.3 4.5 29 5.4 0.0 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_8 PF13181.6 AIN99382.1 - 1.3 9.4 3.4 9.3 6.8 0.1 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat TGT PF01702.18 AIN99383.1 - 4.1e-29 101.8 0.0 3.9e-28 98.6 0.0 1.9 1 1 0 1 1 1 1 Queuine tRNA-ribosyltransferase Peptidase_M48_N PF16491.5 AIN99384.1 - 5.1e-42 143.8 3.5 8.3e-42 143.1 3.5 1.3 1 0 0 1 1 1 1 CAAX prenyl protease N-terminal, five membrane helices Peptidase_M48 PF01435.18 AIN99384.1 - 1.8e-40 138.8 0.0 3e-40 138.1 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M48 Peptidase_M56 PF05569.11 AIN99384.1 - 0.025 13.8 0.0 0.075 12.2 0.1 1.7 2 0 0 2 2 2 0 BlaR1 peptidase M56 DEAD PF00270.29 AIN99385.1 - 5.2e-39 133.8 0.1 9e-39 133.0 0.1 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 AIN99385.1 - 1.1e-23 83.6 0.1 9.1e-20 71.1 0.0 4.0 3 1 1 4 4 4 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 AIN99385.1 - 1.7e-07 31.3 0.6 4e-07 30.2 0.6 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.15 AIN99385.1 - 5.3e-07 29.8 0.0 1.6e-06 28.3 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Viral_helicase1 PF01443.18 AIN99385.1 - 0.042 13.6 0.0 0.14 11.8 0.0 1.8 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase AAA_22 PF13401.6 AIN99385.1 - 2.9 8.1 6.6 1.9 8.8 1.1 3.2 3 1 0 3 3 3 0 AAA domain CcmD PF04995.14 AIN99386.1 - 0.04 14.0 0.2 0.057 13.5 0.2 1.2 1 0 0 1 1 1 0 Heme exporter protein D (CcmD) p450 PF00067.22 AIN99389.1 - 2.6e-56 191.3 0.0 3.4e-56 190.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 RNA_pol_L PF01193.24 AIN99389.1 - 0.29 10.6 1.7 0.47 9.9 0.0 2.1 2 0 0 2 2 2 0 RNA polymerase Rpb3/Rpb11 dimerisation domain Pkinase PF00069.25 AIN99390.1 - 2.3e-69 233.7 0.0 3.2e-69 233.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 AIN99390.1 - 1.1e-28 100.2 0.0 1.7e-28 99.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase PUL PF08324.11 AIN99390.1 - 0.015 14.5 0.0 1.6 7.9 0.0 2.3 2 0 0 2 2 2 0 PUL domain GATA PF00320.27 AIN99390.1 - 0.042 13.5 2.0 0.1 12.2 2.0 1.6 1 0 0 1 1 1 0 GATA zinc finger PsbX PF06596.11 AIN99391.1 - 0.35 10.9 2.5 0.52 10.4 2.5 1.2 1 0 0 1 1 1 0 Photosystem II reaction centre X protein (PsbX) RINGv PF12906.7 AIN99392.1 - 2e-09 37.4 11.2 4.1e-09 36.4 11.2 1.5 1 0 0 1 1 1 1 RING-variant domain PHD PF00628.29 AIN99392.1 - 1.6 8.7 10.4 3 7.8 10.4 1.5 1 0 0 1 1 1 0 PHD-finger WW PF00397.26 AIN99393.1 - 5e-12 45.7 2.3 1.1e-11 44.6 2.3 1.6 1 0 0 1 1 1 1 WW domain zf_CCCH_4 PF18345.1 AIN99393.1 - 1.7e-06 27.9 3.6 3.1e-06 27.0 3.6 1.5 1 0 0 1 1 1 1 Zinc finger domain zf-CCCH PF00642.24 AIN99393.1 - 2.2e-06 27.4 0.7 3.5e-06 26.8 0.7 1.3 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 AIN99393.1 - 2e-05 24.3 1.6 3.4e-05 23.5 1.6 1.4 1 0 0 1 1 1 1 CCCH-type zinc finger Torus PF16131.5 AIN99393.1 - 0.01 16.5 0.1 0.012 16.3 0.1 1.3 1 0 0 1 1 1 0 Torus domain Torus PF16131.5 AIN99395.1 - 6.9e-07 29.9 0.1 1.2e-06 29.1 0.1 1.3 1 0 0 1 1 1 1 Torus domain zf_CCCH_4 PF18345.1 AIN99395.1 - 7.2e-07 29.1 2.6 1e-06 28.6 2.6 1.2 1 0 0 1 1 1 1 Zinc finger domain zf-CCCH_4 PF18044.1 AIN99395.1 - 2.2e-06 27.3 1.2 3.2e-06 26.8 1.2 1.2 1 0 0 1 1 1 1 CCCH-type zinc finger zf-CCCH PF00642.24 AIN99395.1 - 0.0016 18.3 0.3 0.0023 17.8 0.3 1.2 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.6 AIN99395.1 - 0.0028 18.1 2.3 0.0047 17.3 2.3 1.3 1 0 0 1 1 1 1 RNA-binding, Nab2-type zinc finger SET PF00856.28 AIN99396.1 - 2.8e-13 50.6 0.0 1.3e-12 48.4 0.0 1.9 1 1 0 1 1 1 1 SET domain OSTMP1 PF09777.9 AIN99396.1 - 0.0073 15.7 0.2 0.012 15.1 0.2 1.3 1 0 0 1 1 1 1 Osteopetrosis-associated transmembrane protein 1 precursor Proteasome PF00227.26 AIN99399.1 - 1.7e-42 145.1 0.1 2.2e-42 144.7 0.1 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 AIN99399.1 - 1.2e-08 34.5 0.1 1.2e-08 34.5 0.1 1.7 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature Torus PF16131.5 AIN99400.1 - 0.0015 19.2 0.1 0.0029 18.3 0.1 1.4 1 0 0 1 1 1 1 Torus domain Inhibitor_I36 PF03995.13 AIN99400.1 - 0.017 15.0 0.1 1.9 8.4 0.0 3.0 3 0 0 3 3 3 0 Peptidase inhibitor family I36 PetM PF08041.11 AIN99400.1 - 0.51 10.0 2.6 0.86 9.2 2.6 1.4 1 0 0 1 1 1 0 PetM family of cytochrome b6f complex subunit 7 VIT1 PF01988.19 AIN99401.1 - 4.8e-51 173.7 4.4 5.9e-51 173.4 4.4 1.1 1 0 0 1 1 1 1 VIT family Exotox-A_target PF09102.10 AIN99401.1 - 0.087 12.8 0.0 0.15 12.0 0.0 1.3 1 0 0 1 1 1 0 Exotoxin A, targeting THF_DHG_CYH_C PF02882.19 AIN99402.1 - 0.15 11.4 0.0 0.26 10.6 0.0 1.4 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain DUF3295 PF11702.8 AIN99403.1 - 0.33 10.3 1.8 5.3 6.3 1.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3295) NAD_binding_2 PF03446.15 AIN99404.1 - 0.021 15.0 0.5 0.027 14.6 0.5 1.2 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase DUF1501 PF07394.12 AIN99404.1 - 0.41 9.6 2.4 0.45 9.5 2.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1501) Casc1_N PF15927.5 AIN99404.1 - 1.4 8.6 25.6 6.4 6.4 25.9 1.8 1 1 0 1 1 1 0 Cancer susceptibility candidate 1 N-terminus MAP7 PF05672.11 AIN99404.1 - 4 7.1 21.7 12 5.6 21.7 1.7 1 1 0 1 1 1 0 MAP7 (E-MAP-115) family MAP7 PF05672.11 AIN99405.1 - 0.0041 16.8 46.8 0.025 14.3 15.2 2.9 1 1 1 2 2 2 1 MAP7 (E-MAP-115) family Casc1_N PF15927.5 AIN99405.1 - 0.14 11.8 52.1 3.9 7.1 20.5 2.6 1 1 1 2 2 2 0 Cancer susceptibility candidate 1 N-terminus Creatininase PF02633.14 AIN99405.1 - 0.28 10.6 11.2 0.31 10.5 11.2 1.1 1 0 0 1 1 1 0 Creatinine amidohydrolase Sarcoglycan_1 PF04790.13 AIN99405.1 - 0.7 9.2 4.8 0.84 8.9 4.1 1.5 1 1 0 1 1 1 0 Sarcoglycan complex subunit protein DUF3332 PF11810.8 AIN99405.1 - 2.2 7.9 5.3 4.4 6.9 5.3 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF3332) SH3_16 PF18348.1 AIN99405.1 - 6.2 6.7 8.2 11 5.9 0.6 3.3 1 1 3 4 4 4 0 Bacterial dipeptidyl-peptidase Sh3 domain F-protein PF00469.20 AIN99405.1 - 8.9 5.8 7.0 11 5.6 7.0 1.2 1 0 0 1 1 1 0 Negative factor, (F-Protein) or Nef XPG_I PF00867.18 AIN99406.1 - 4.6e-31 107.0 0.1 8.5e-31 106.2 0.1 1.5 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.17 AIN99406.1 - 5.7e-27 94.2 0.0 1.1e-26 93.3 0.0 1.5 1 0 0 1 1 1 1 XPG N-terminal domain 5_3_exonuc PF01367.20 AIN99406.1 - 8.3e-06 26.3 0.0 7.5e-05 23.2 0.0 2.2 2 0 0 2 2 2 1 5'-3' exonuclease, C-terminal SAM fold XRN_N PF03159.18 AIN99406.1 - 0.035 13.5 0.0 0.046 13.1 0.0 1.2 1 0 0 1 1 1 0 XRN 5'-3' exonuclease N-terminus Peptidase_M20 PF01546.28 AIN99406.1 - 0.16 11.6 0.0 0.31 10.7 0.0 1.4 1 0 0 1 1 1 0 Peptidase family M20/M25/M40 EcsC PF12787.7 AIN99408.1 - 3 7.4 7.7 0.27 10.9 1.2 2.1 2 0 0 2 2 2 0 EcsC protein family PP-binding PF00550.25 AIN99409.1 - 1.1e-10 41.7 0.1 1.4e-10 41.3 0.1 1.2 1 0 0 1 1 1 1 Phosphopantetheine attachment site MM_CoA_mutase PF01642.22 AIN99410.1 - 5.7e-227 754.3 1.7 6.8e-227 754.0 1.7 1.0 1 0 0 1 1 1 1 Methylmalonyl-CoA mutase B12-binding PF02310.19 AIN99410.1 - 1e-12 48.1 0.1 2.6e-12 46.8 0.1 1.7 1 0 0 1 1 1 1 B12 binding domain HisG_C PF08029.11 AIN99410.1 - 0.058 13.6 0.0 0.16 12.1 0.0 1.8 1 0 0 1 1 1 0 HisG, C-terminal domain TIP120 PF08623.10 AIN99411.1 - 2.9e-08 33.7 0.2 2e-07 30.9 0.0 2.4 2 0 0 2 2 2 1 TATA-binding protein interacting (TIP20) Adaptin_N PF01602.20 AIN99411.1 - 0.003 16.2 8.9 0.012 14.2 0.3 3.3 3 0 0 3 3 3 2 Adaptin N terminal region Spidroin_MaSp PF11260.8 AIN99411.1 - 0.95 9.8 11.6 0.78 10.1 0.1 4.2 3 0 0 3 3 3 0 Major ampullate spidroin 1 and 2 Urb2 PF10441.9 AIN99412.1 - 0.13 12.2 2.1 0.16 11.8 0.5 2.1 2 1 0 2 2 2 0 Urb2/Npa2 family HTH_53 PF18606.1 AIN99412.1 - 0.13 12.0 0.0 0.33 10.7 0.0 1.6 1 0 0 1 1 1 0 Zap helix turn helix N-terminal domain TSNAXIP1_N PF15739.5 AIN99413.1 - 3.7e-18 65.9 4.8 3.7e-18 65.9 4.8 2.7 2 0 0 2 2 2 1 Translin-associated factor X-interacting N-terminus Arg_decarbox_C PF17944.1 AIN99413.1 - 1.2 9.8 3.9 26 5.5 0.3 3.7 4 0 0 4 4 4 0 Arginine decarboxylase C-terminal helical extension RRM_1 PF00076.22 AIN99415.1 - 3e-17 62.2 0.0 1.3e-08 34.5 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) AAA PF00004.29 AIN99416.1 - 5.1e-36 124.0 0.0 9.8e-35 119.9 0.0 2.5 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 AIN99416.1 - 4.7e-08 32.7 0.1 1.3e-07 31.3 0.1 1.7 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 AIN99416.1 - 6.7e-08 33.1 0.2 0.032 14.6 0.0 3.4 2 1 0 3 3 3 2 AAA ATPase domain Rad17 PF03215.15 AIN99416.1 - 9e-05 22.5 0.0 0.0084 16.0 0.0 2.4 2 0 0 2 2 2 1 Rad17 P-loop domain AAA_5 PF07728.14 AIN99416.1 - 0.0023 17.9 0.0 0.01 15.8 0.0 2.2 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 AIN99416.1 - 0.0064 16.8 0.1 7.8 6.8 0.1 3.7 2 2 2 4 4 4 1 AAA domain RNA_helicase PF00910.22 AIN99416.1 - 0.012 16.0 0.0 0.28 11.6 0.0 2.4 2 0 0 2 2 2 0 RNA helicase DUF815 PF05673.13 AIN99416.1 - 0.035 13.3 0.0 1.9 7.6 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_33 PF13671.6 AIN99416.1 - 0.041 14.1 0.0 0.12 12.5 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 AIN99416.1 - 0.055 13.0 0.0 1.1 8.7 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_14 PF13173.6 AIN99416.1 - 0.075 13.1 0.0 0.63 10.1 0.0 2.1 2 0 0 2 2 2 0 AAA domain RuvB_N PF05496.12 AIN99416.1 - 0.092 12.5 0.0 0.22 11.3 0.0 1.6 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain ATPase_2 PF01637.18 AIN99416.1 - 0.14 12.1 0.0 1.3 8.9 0.0 2.3 2 1 1 3 3 3 0 ATPase domain predominantly from Archaea Herpes_UL49_5 PF05702.11 AIN99417.1 - 0.053 13.6 0.1 0.1 12.7 0.1 1.4 1 0 0 1 1 1 0 Herpesvirus UL49.5 envelope/tegument protein Nup96 PF12110.8 AIN99418.1 - 6e-34 117.5 0.0 1e-33 116.8 0.0 1.3 1 0 0 1 1 1 1 Nuclear protein 96 Nucleoporin2 PF04096.14 AIN99418.1 - 7e-14 52.2 0.0 1.4e-13 51.2 0.0 1.5 1 0 0 1 1 1 1 Nucleoporin autopeptidase APG9 PF04109.16 AIN99419.1 - 1.2e-59 202.7 5.9 2.3e-59 201.7 5.9 1.4 1 1 0 1 1 1 1 Autophagy protein Apg9 KIP1 PF07765.12 AIN99420.1 - 0.0033 17.5 2.0 0.16 12.1 0.4 2.2 1 1 1 2 2 2 2 KIP1-like protein DnaJ PF00226.31 AIN99421.1 - 7.2e-25 86.9 0.7 1.3e-24 86.1 0.7 1.4 1 0 0 1 1 1 1 DnaJ domain TrbE PF11100.8 AIN99421.1 - 0.11 12.8 0.4 0.22 11.8 0.4 1.4 1 0 0 1 1 1 0 Conjugal transfer protein TrbE PfkB PF00294.24 AIN99422.1 - 1.4e-66 224.9 0.0 1.6e-66 224.7 0.0 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.12 AIN99422.1 - 5e-08 32.6 0.0 7.3e-08 32.1 0.0 1.2 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase Mur_ligase PF01225.25 AIN99422.1 - 0.0094 16.3 0.1 0.077 13.3 0.0 2.6 2 1 1 3 3 3 1 Mur ligase family, catalytic domain Gly_reductase PF09338.11 AIN99422.1 - 0.026 12.9 2.5 0.064 11.6 0.2 2.0 2 0 0 2 2 2 0 Glycine/sarcosine/betaine reductase component B subunits Brix PF04427.18 AIN99425.1 - 2.1e-27 96.5 0.1 4e-27 95.6 0.1 1.5 1 0 0 1 1 1 1 Brix domain Vasohibin PF14822.6 AIN99426.1 - 4.8e-47 160.3 0.0 7.9e-47 159.5 0.0 1.3 1 0 0 1 1 1 1 Vasohibin ABC_membrane_2 PF06472.15 AIN99427.1 - 4.2e-25 88.7 0.8 4.2e-25 88.7 0.8 1.7 2 0 0 2 2 2 1 ABC transporter transmembrane region 2 ABC_tran PF00005.27 AIN99427.1 - 6.2e-14 52.7 0.0 1.3e-13 51.6 0.0 1.6 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 AIN99427.1 - 2.5e-07 30.4 0.0 1e-05 25.1 0.0 2.2 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain NACHT PF05729.12 AIN99427.1 - 8e-05 22.6 0.0 0.00015 21.7 0.0 1.5 1 0 0 1 1 1 1 NACHT domain ABC_membrane PF00664.23 AIN99427.1 - 0.0002 21.1 1.5 0.0002 21.1 1.5 1.6 2 0 0 2 2 2 1 ABC transporter transmembrane region AAA_22 PF13401.6 AIN99427.1 - 0.0051 17.1 0.5 0.074 13.3 0.5 2.4 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 AIN99427.1 - 0.012 16.0 0.0 0.028 14.8 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain AAA_23 PF13476.6 AIN99427.1 - 0.016 15.7 0.0 0.028 14.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain HTH_43 PF09904.9 AIN99427.1 - 0.043 13.8 0.1 0.1 12.6 0.1 1.6 1 0 0 1 1 1 0 Winged helix-turn helix AAA_21 PF13304.6 AIN99427.1 - 0.058 13.2 0.0 0.25 11.1 0.0 1.8 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system DUF3584 PF12128.8 AIN99427.1 - 0.12 9.9 0.0 0.17 9.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) AAA_15 PF13175.6 AIN99427.1 - 0.19 11.4 0.0 0.31 10.7 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain SH3_3 PF08239.11 AIN99428.1 - 0.051 13.9 0.0 9.1 6.6 0.0 2.8 2 0 0 2 2 2 0 Bacterial SH3 domain Peptidase_C2 PF00648.21 AIN99429.1 - 3.2e-67 226.7 0.0 1.6e-33 116.0 0.0 2.3 2 0 0 2 2 2 2 Calpain family cysteine protease Calpain_III PF01067.22 AIN99429.1 - 6.5e-15 55.6 0.1 7.3e-08 32.8 0.0 3.5 3 0 0 3 3 3 2 Calpain large subunit, domain III DUF1043 PF06295.12 AIN99429.1 - 3.1 7.8 7.3 0.44 10.6 0.2 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1043) Peptidase_C2 PF00648.21 AIN99430.1 - 6.5e-19 68.1 0.0 9.7e-19 67.5 0.0 1.2 1 0 0 1 1 1 1 Calpain family cysteine protease Calpain_III PF01067.22 AIN99430.1 - 3.1e-06 27.5 0.0 1.1e-05 25.7 0.0 1.9 2 0 0 2 2 2 1 Calpain large subunit, domain III Peptidase_C2 PF00648.21 AIN99431.1 - 1.2e-98 329.8 0.0 2.2e-37 128.7 0.0 3.2 3 0 0 3 3 3 3 Calpain family cysteine protease Calpain_III PF01067.22 AIN99431.1 - 6.3e-20 71.9 0.0 1e-06 29.0 0.0 4.1 4 0 0 4 4 4 3 Calpain large subunit, domain III DUF3470 PF11953.8 AIN99431.1 - 5.4 7.1 11.2 7.5 6.6 0.0 5.4 5 0 0 5 5 5 0 Domain of unknown function (DUF3470) EDR1 PF14381.6 AIN99431.1 - 8.3 6.1 5.8 14 5.4 0.2 4.1 4 0 0 4 4 4 0 Ethylene-responsive protein kinase Le-CTR1 Peptidase_C2 PF00648.21 AIN99432.1 - 4.3e-94 314.9 0.0 3.9e-35 121.3 0.0 3.2 3 0 0 3 3 3 3 Calpain family cysteine protease Calpain_III PF01067.22 AIN99432.1 - 1.3e-11 44.9 0.0 0.00019 21.7 0.0 3.9 3 0 0 3 3 3 2 Calpain large subunit, domain III Fib_alpha PF08702.10 AIN99432.1 - 0.44 10.7 6.0 37 4.5 0.7 5.6 4 0 0 4 4 4 0 Fibrinogen alpha/beta chain family Radial_spoke_3 PF06098.11 AIN99433.1 - 5.3e-108 360.6 27.9 6.4e-108 360.4 27.9 1.1 1 0 0 1 1 1 1 Radial spoke protein 3 Amastin PF07344.11 AIN99435.1 - 2.8e-08 33.8 5.8 2.8e-08 33.8 5.8 1.7 2 0 0 2 2 2 1 Amastin surface glycoprotein Rep_fac_C PF08542.11 AIN99436.1 - 1.9e-18 66.6 0.1 1.3e-17 64.0 0.0 2.2 2 0 0 2 2 2 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.6 AIN99436.1 - 1.9e-12 47.3 0.0 1.2e-11 44.7 0.0 2.0 1 1 0 1 1 1 1 DNA polymerase III, delta subunit AAA PF00004.29 AIN99436.1 - 1.7e-11 44.6 0.2 7.7e-11 42.5 0.0 2.2 3 0 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 AIN99436.1 - 1.8e-07 31.3 0.0 3.3e-07 30.4 0.0 1.4 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_22 PF13401.6 AIN99436.1 - 4.8e-07 30.1 0.0 1.6e-06 28.5 0.0 1.8 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 AIN99436.1 - 2.3e-05 23.9 0.1 0.00038 19.9 0.1 2.2 1 1 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_16 PF13191.6 AIN99436.1 - 3e-05 24.5 0.8 0.00051 20.5 0.8 2.4 1 1 0 1 1 1 1 AAA ATPase domain AAA_19 PF13245.6 AIN99436.1 - 0.0001 22.6 1.1 0.0071 16.7 0.1 2.6 2 1 0 2 2 2 1 AAA domain RuvB_N PF05496.12 AIN99436.1 - 0.00012 21.9 0.1 0.0004 20.2 0.0 2.0 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_assoc_2 PF16193.5 AIN99436.1 - 0.00014 22.1 0.0 0.00035 20.9 0.0 1.7 1 0 0 1 1 1 1 AAA C-terminal domain DNA_pol3_delta PF06144.13 AIN99436.1 - 0.00061 19.6 0.1 0.0013 18.5 0.1 1.5 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA_24 PF13479.6 AIN99436.1 - 0.0014 18.4 0.0 0.0026 17.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 AIN99436.1 - 0.0047 16.7 0.1 0.014 15.1 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.6 AIN99436.1 - 0.0056 16.5 0.0 0.012 15.4 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_25 PF13481.6 AIN99436.1 - 0.0074 15.9 0.4 0.018 14.6 0.1 1.9 2 1 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 AIN99436.1 - 0.01 16.2 0.0 0.042 14.2 0.0 2.1 3 0 0 3 3 2 0 RNA helicase AAA_5 PF07728.14 AIN99436.1 - 0.014 15.4 0.0 0.3 11.1 0.0 2.4 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) MCM PF00493.23 AIN99436.1 - 0.031 13.4 0.2 2.8 7.0 0.0 2.5 2 1 1 3 3 3 0 MCM P-loop domain DUF2075 PF09848.9 AIN99436.1 - 0.035 13.3 0.0 0.057 12.7 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_14 PF13173.6 AIN99436.1 - 0.043 13.9 0.0 0.19 11.7 0.0 2.0 1 1 0 1 1 1 0 AAA domain PrpR_N PF06506.11 AIN99436.1 - 0.067 12.8 0.0 0.17 11.5 0.0 1.7 1 0 0 1 1 1 0 Propionate catabolism activator AAA_18 PF13238.6 AIN99436.1 - 0.07 13.7 0.0 0.16 12.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 AIN99436.1 - 0.082 13.1 0.0 0.23 11.6 0.0 1.8 1 0 0 1 1 1 0 AAA domain Pkinase PF00069.25 AIN99437.1 - 1.6e-61 208.0 0.0 1.8e-61 207.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 AIN99437.1 - 1e-26 93.8 0.0 1.4e-26 93.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 AIN99437.1 - 0.005 15.7 0.0 0.03 13.1 0.0 1.9 2 0 0 2 2 2 1 Fungal protein kinase APH PF01636.23 AIN99437.1 - 0.013 15.5 0.0 0.028 14.4 0.0 1.6 1 1 1 2 2 2 0 Phosphotransferase enzyme family FTA2 PF13095.6 AIN99437.1 - 0.049 13.3 0.0 8.2 6.0 0.0 2.3 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Lambda_Kil PF06301.11 AIN99437.1 - 0.2 11.3 0.0 0.35 10.5 0.0 1.4 1 0 0 1 1 1 0 Bacteriophage lambda Kil protein zf-RING_2 PF13639.6 AIN99438.1 - 6.2e-09 36.1 9.4 6.2e-09 36.1 9.4 2.4 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.25 AIN99438.1 - 2.7e-07 30.3 8.2 2.7e-07 30.3 8.2 2.3 3 0 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 AIN99438.1 - 6.3e-06 26.0 8.0 6.3e-06 26.0 8.0 2.7 2 1 1 3 3 2 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 AIN99438.1 - 9.5e-06 25.4 6.3 9.5e-06 25.4 6.3 2.8 2 1 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 AIN99438.1 - 2.7e-05 24.1 6.7 2.7e-05 24.1 6.7 2.5 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 AIN99438.1 - 6.9e-05 22.6 7.8 6.9e-05 22.6 7.8 2.6 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 AIN99438.1 - 8.7e-05 22.3 8.7 8.7e-05 22.3 8.7 2.8 2 1 0 2 2 2 1 Prokaryotic RING finger family 4 zf-rbx1 PF12678.7 AIN99438.1 - 0.00079 19.7 10.7 0.00079 19.7 10.7 2.8 2 1 0 2 2 2 1 RING-H2 zinc finger domain zf-UDP PF14569.6 AIN99438.1 - 0.00092 19.3 2.3 0.00092 19.3 2.3 2.0 2 0 0 2 2 1 1 Zinc-binding RING-finger zf-C3HC4_4 PF15227.6 AIN99438.1 - 0.031 14.4 5.6 0.031 14.4 5.6 2.5 2 1 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-ACC PF17848.1 AIN99438.1 - 0.076 13.1 0.6 0.32 11.1 0.6 2.1 1 0 0 1 1 1 0 Acetyl-coA carboxylase zinc finger domain zf-RING_11 PF17123.5 AIN99438.1 - 0.26 11.1 6.2 0.97 9.2 6.2 2.0 1 0 0 1 1 1 0 RING-like zinc finger FYVE_2 PF02318.16 AIN99438.1 - 0.7 10.1 11.8 2.5 8.3 1.4 2.6 2 0 0 2 2 2 0 FYVE-type zinc finger zf-ANAPC11 PF12861.7 AIN99438.1 - 0.78 9.8 12.1 0.046 13.8 5.4 2.3 2 1 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger zinc_ribbon_15 PF17032.5 AIN99438.1 - 1.7 9.4 9.2 10 7.0 3.3 2.8 2 0 0 2 2 2 0 zinc-ribbon family zf-RING_4 PF14570.6 AIN99438.1 - 3.4 7.5 21.7 0.068 13.0 8.1 3.1 2 1 0 2 2 2 0 RING/Ubox like zinc-binding domain DZR PF12773.7 AIN99438.1 - 3.8 7.6 20.9 0.039 14.0 5.3 3.3 3 1 1 4 4 4 0 Double zinc ribbon FANCL_C PF11793.8 AIN99438.1 - 4.5 7.5 18.3 3.1 8.0 3.3 3.1 2 1 0 2 2 2 0 FANCL C-terminal domain zinc_ribbon_2 PF13240.6 AIN99438.1 - 5.9 6.8 7.1 35 4.3 4.5 3.0 2 1 0 2 2 2 0 zinc-ribbon domain ANAPC4_WD40 PF12894.7 AIN99439.1 - 6.4e-07 29.6 0.1 0.48 10.7 0.0 3.9 4 0 0 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 AIN99439.1 - 1e-05 26.2 1.3 11 7.0 0.0 5.1 4 0 0 4 4 4 2 WD domain, G-beta repeat LisH PF08513.11 AIN99439.1 - 6.1e-05 22.8 0.2 0.00011 22.0 0.2 1.4 1 0 0 1 1 1 1 LisH LisH_TPL PF17814.1 AIN99439.1 - 0.0085 15.7 0.0 0.017 14.8 0.0 1.5 1 0 0 1 1 1 1 LisH-like dimerisation domain DUF4471 PF14740.6 AIN99440.1 - 2.9e-67 227.1 0.0 5.6e-67 226.1 0.0 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF4471) DUF4470 PF14737.6 AIN99440.1 - 4.5e-16 58.8 0.1 3.8e-15 55.9 0.1 2.2 1 1 0 1 1 1 1 Domain of unknown function (DUF4470) DUF148 PF02520.17 AIN99440.1 - 0.7 10.0 3.8 2.9 8.0 0.4 2.8 2 1 0 3 3 3 0 Domain of unknown function DUF148 MRPL52 PF18699.1 AIN99441.1 - 2.2 8.5 4.9 3.7 7.8 0.0 3.2 3 0 0 3 3 3 0 Mitoribosomal protein mL52 MRP-S28 PF10213.9 AIN99444.1 - 0.001 19.5 0.0 0.003 18.0 0.0 1.8 1 0 0 1 1 1 1 Mitochondrial ribosomal subunit protein DUF5075 PF16825.5 AIN99447.1 - 1.5e-06 28.0 3.2 4.9e-06 26.4 3.2 1.9 1 1 0 1 1 1 1 IGP family C-type lectin domain MGC-24 PF05283.11 AIN99447.1 - 0.0017 18.8 10.0 0.0017 18.8 10.0 2.6 2 1 1 3 3 3 1 Multi-glycosylated core protein 24 (MGC-24), sialomucin TMEM154 PF15102.6 AIN99447.1 - 0.0042 17.0 4.7 0.0042 17.0 4.7 1.7 2 0 0 2 2 2 1 TMEM154 protein family DUF4366 PF14283.6 AIN99447.1 - 0.0074 16.3 0.6 0.015 15.4 0.6 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4366) DUF5305 PF17231.2 AIN99447.1 - 1.4 8.3 6.6 2.4 7.5 6.6 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5305) Hum_adeno_E3A PF05393.11 AIN99447.1 - 2.5 8.2 7.1 12 6.0 0.2 2.7 2 1 0 2 2 2 0 Human adenovirus early E3A glycoprotein AJAP1_PANP_C PF15298.6 AIN99447.1 - 3 8.0 21.1 1.8 8.7 18.5 1.9 1 1 1 2 2 2 0 AJAP1/PANP C-terminus Aa_trans PF01490.18 AIN99448.1 - 2.1e-51 175.0 33.1 2.6e-51 174.6 33.1 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Holin_SPP1 PF04688.13 AIN99448.1 - 1.2 9.4 0.0 1.2 9.4 0.0 2.8 3 0 0 3 3 3 0 SPP1 phage holin Aa_trans PF01490.18 AIN99449.1 - 7e-41 140.3 36.7 8.6e-41 140.0 36.7 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 AIN99449.1 - 4.4e-09 35.9 21.3 4.4e-09 35.9 21.3 1.7 2 0 0 2 2 2 1 Tryptophan/tyrosine permease family AA_permease_2 PF13520.6 AIN99449.1 - 4.4e-07 29.1 26.3 4.4e-07 29.1 26.3 1.9 2 0 0 2 2 2 1 Amino acid permease VIT1 PF01988.19 AIN99449.1 - 0.034 14.0 0.0 0.034 14.0 0.0 3.4 3 0 0 3 3 3 0 VIT family DUF2207 PF09972.9 AIN99449.1 - 1.5 7.5 0.0 1.5 7.5 0.0 3.2 2 1 1 3 3 3 0 Predicted membrane protein (DUF2207) DUF1860 PF08949.10 AIN99450.1 - 0.0051 16.6 0.1 0.46 10.2 0.0 2.7 2 0 0 2 2 2 1 Domain of unknown function (DUF1860) LRR_4 PF12799.7 AIN99450.1 - 0.037 14.5 0.1 0.55 10.7 0.0 2.9 3 1 2 5 5 5 0 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 AIN99450.1 - 0.28 11.0 0.5 25 4.7 0.0 3.3 4 0 0 4 4 4 0 Leucine rich repeat UBA PF00627.31 AIN99453.1 - 3.6e-08 33.2 1.5 3.8e-08 33.1 0.1 1.9 2 0 0 2 2 2 1 UBA/TS-N domain Peptidase_M91 PF14891.6 AIN99453.1 - 0.095 13.0 0.5 0.17 12.2 0.0 1.6 2 0 0 2 2 2 0 Effector protein UBA_4 PF14555.6 AIN99453.1 - 0.14 12.0 0.0 0.32 10.9 0.0 1.6 1 0 0 1 1 1 0 UBA-like domain NAD_binding_1 PF00175.21 AIN99454.1 - 6.9e-19 68.5 0.0 9.6e-19 68.1 0.0 1.2 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.12 AIN99454.1 - 2.3e-05 24.6 0.0 0.0003 20.9 0.0 2.1 2 0 0 2 2 2 1 Ferric reductase NAD binding domain Oxidored_q6 PF01058.22 AIN99455.1 - 2.8e-19 69.3 0.0 3.6e-19 68.9 0.0 1.2 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase, 20 Kd subunit Dabb PF07876.12 AIN99456.1 - 1.7e-08 35.0 0.0 2.4e-08 34.5 0.0 1.3 1 0 0 1 1 1 1 Stress responsive A/B Barrel Domain DsbC_N PF10411.9 AIN99456.1 - 0.062 12.8 0.0 0.089 12.3 0.0 1.4 1 0 0 1 1 1 0 Disulfide bond isomerase protein N-terminus Dabb PF07876.12 AIN99457.1 - 0.00026 21.5 0.0 0.00034 21.2 0.0 1.3 1 1 0 1 1 1 1 Stress responsive A/B Barrel Domain Ras PF00071.22 AIN99458.1 - 3.4e-64 215.3 0.6 3.9e-64 215.1 0.6 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 AIN99458.1 - 8e-37 126.1 0.1 1.4e-36 125.4 0.1 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 AIN99458.1 - 7.3e-16 58.1 0.1 8.8e-16 57.8 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 AIN99458.1 - 5.7e-07 29.6 0.5 0.0098 15.8 0.2 2.3 1 1 1 2 2 2 2 RsgA GTPase Gtr1_RagA PF04670.12 AIN99458.1 - 2.1e-06 27.3 0.1 2.5e-06 27.0 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 AIN99458.1 - 3.5e-05 23.3 0.2 4.6e-05 22.9 0.2 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.27 AIN99458.1 - 9.2e-05 22.1 0.3 0.00021 20.9 0.3 1.7 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 AIN99458.1 - 0.00018 21.6 0.1 0.00045 20.3 0.0 1.6 1 1 1 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 AIN99458.1 - 0.0007 19.1 0.1 0.0038 16.8 0.1 1.9 1 1 0 1 1 1 1 Ferrous iron transport protein B AAA PF00004.29 AIN99458.1 - 0.0059 17.0 0.0 0.41 11.1 0.0 2.3 1 1 1 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 AIN99458.1 - 0.018 15.4 0.0 0.03 14.7 0.0 1.4 1 1 0 1 1 1 0 AAA ATPase domain ABC_tran PF00005.27 AIN99458.1 - 0.025 15.1 0.2 0.15 12.6 0.2 1.9 1 1 0 1 1 1 0 ABC transporter G-alpha PF00503.20 AIN99458.1 - 0.033 13.4 3.9 0.14 11.3 0.7 2.5 1 1 1 2 2 2 0 G-protein alpha subunit AAA_22 PF13401.6 AIN99458.1 - 0.047 14.0 0.0 0.13 12.6 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA_29 PF13555.6 AIN99458.1 - 0.066 13.0 0.0 0.14 11.9 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain TniB PF05621.11 AIN99458.1 - 0.11 12.0 0.0 0.25 10.7 0.0 1.6 2 0 0 2 2 2 0 Bacterial TniB protein DUF4093 PF13331.6 AIN99459.1 - 0.24 11.9 0.1 0.92 10.0 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4093) MCU PF04678.13 AIN99460.1 - 1.3e-40 139.4 0.0 1.9e-40 138.8 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial calcium uniporter Glyoxalase_4 PF13669.6 AIN99460.1 - 0.066 13.5 0.0 0.16 12.3 0.0 1.7 1 1 0 1 1 1 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily LRR_6 PF13516.6 AIN99461.1 - 0.0002 21.2 8.4 0.016 15.2 0.6 3.8 3 0 0 3 3 3 2 Leucine Rich repeat Glutaredoxin PF00462.24 AIN99462.1 - 8e-14 51.6 0.2 1e-13 51.2 0.2 1.2 1 0 0 1 1 1 1 Glutaredoxin GST_N_3 PF13417.6 AIN99462.1 - 2e-05 24.9 0.0 2.3e-05 24.7 0.0 1.1 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Thioredoxin_3 PF13192.6 AIN99462.1 - 0.0012 18.8 0.1 0.0017 18.4 0.1 1.2 1 0 0 1 1 1 1 Thioredoxin domain DSBA PF01323.20 AIN99462.1 - 0.0021 17.8 0.3 0.42 10.4 0.2 2.1 1 1 1 2 2 2 2 DSBA-like thioredoxin domain Thioredoxin_4 PF13462.6 AIN99462.1 - 0.0038 17.4 0.4 0.38 10.9 0.0 2.1 1 1 1 2 2 2 1 Thioredoxin Thioredoxin_2 PF13098.6 AIN99462.1 - 0.038 14.4 0.4 0.048 14.1 0.4 1.4 1 1 0 1 1 1 0 Thioredoxin-like domain DUF836 PF05768.14 AIN99462.1 - 0.045 14.2 0.0 0.051 14.0 0.0 1.2 1 0 0 1 1 1 0 Glutaredoxin-like domain (DUF836) Zn_Tnp_IS1595 PF12760.7 AIN99462.1 - 0.091 12.7 0.1 0.15 12.1 0.1 1.3 1 0 0 1 1 1 0 Transposase zinc-ribbon domain Beta_helix PF13229.6 AIN99463.1 - 7.5e-100 331.3 103.8 3.7e-15 56.1 4.8 16.2 10 5 4 15 15 15 13 Right handed beta helix region NosD PF05048.13 AIN99463.1 - 8.8e-79 264.2 45.0 8.6e-14 51.4 5.8 15.3 10 4 5 15 15 15 13 Periplasmic copper-binding protein (NosD) End3 PF12761.7 AIN99463.1 - 0.04 14.1 0.1 0.076 13.2 0.1 1.4 1 0 0 1 1 1 0 Actin cytoskeleton-regulatory complex protein END3 FliJ PF02050.16 AIN99463.1 - 0.19 11.9 1.0 0.4 10.9 1.0 1.4 1 0 0 1 1 1 0 Flagellar FliJ protein DUF1565 PF07602.11 AIN99463.1 - 0.36 10.1 61.7 0.32 10.3 0.0 12.9 9 5 4 15 15 15 0 Protein of unknown function (DUF1565) SKI PF01202.22 AIN99464.1 - 0.1 12.7 1.2 2.4 8.3 1.0 2.3 2 0 0 2 2 2 0 Shikimate kinase SDH_alpha PF03313.15 AIN99464.1 - 0.2 11.3 0.2 0.42 10.2 0.1 1.6 2 0 0 2 2 2 0 Serine dehydratase alpha chain HrpB1_HrpK PF09613.10 AIN99465.1 - 0.021 14.5 0.5 0.086 12.5 0.3 2.2 2 0 0 2 2 2 0 Bacterial type III secretion protein (HrpB1_HrpK) PreAtp-grasp PF18604.1 AIN99465.1 - 0.046 13.4 0.1 0.22 11.2 0.3 2.1 2 0 0 2 2 2 0 Pre ATP-grasp domain WD40 PF00400.32 AIN99467.1 - 1.8e-05 25.4 12.6 0.13 13.2 0.0 6.3 5 0 0 5 5 5 2 WD domain, G-beta repeat PQQ_3 PF13570.6 AIN99467.1 - 0.67 10.5 4.0 16 6.1 0.0 5.1 4 0 0 4 4 4 0 PQQ-like domain DUF1126 PF06565.12 AIN99468.1 - 2.5e-77 255.5 2.6 1.1e-24 86.2 0.1 3.3 3 0 0 3 3 3 3 DUF1126 PH-like domain EF-hand_7 PF13499.6 AIN99468.1 - 5.2e-06 26.8 5.8 1.2e-05 25.6 0.0 3.5 3 1 1 4 4 4 1 EF-hand domain pair EF-hand_8 PF13833.6 AIN99468.1 - 5.3e-05 23.0 0.4 0.17 11.7 0.0 3.3 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 AIN99468.1 - 0.0046 16.4 0.2 18 5.1 0.0 4.7 4 0 0 4 4 4 1 EF hand EF-hand_6 PF13405.6 AIN99468.1 - 0.0053 16.6 0.3 5.2 7.3 0.1 4.2 4 0 0 4 4 4 1 EF-hand domain Sep15_SelM PF08806.11 AIN99469.1 - 0.011 15.9 0.0 0.019 15.1 0.0 1.5 1 0 0 1 1 1 0 Sep15/SelM redox domain NEL PF14496.6 AIN99469.1 - 0.16 11.3 0.4 0.21 11.0 0.4 1.2 1 0 0 1 1 1 0 C-terminal novel E3 ligase, LRR-interacting E1_dh PF00676.20 AIN99470.1 - 1.1e-55 188.7 0.0 1.8e-55 188.0 0.0 1.2 1 0 0 1 1 1 1 Dehydrogenase E1 component Transket_pyr PF02779.24 AIN99470.1 - 5.5e-48 163.0 0.0 9.3e-48 162.2 0.0 1.4 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain OxoGdeHyase_C PF16870.5 AIN99470.1 - 1.2e-35 122.5 0.1 2.4e-35 121.5 0.1 1.5 1 0 0 1 1 1 1 2-oxoglutarate dehydrogenase C-terminal 2-oxogl_dehyd_N PF16078.5 AIN99470.1 - 0.00046 19.7 0.2 0.0011 18.5 0.2 1.6 1 0 0 1 1 1 1 2-oxoglutarate dehydrogenase N-terminus PIP5K PF01504.18 AIN99471.1 - 9.1e-34 116.9 0.0 1.3e-15 57.4 0.0 3.2 2 1 1 3 3 3 3 Phosphatidylinositol-4-phosphate 5-Kinase FYVE PF01363.21 AIN99471.1 - 6.8e-15 55.0 5.4 1.7e-14 53.7 5.4 1.7 1 0 0 1 1 1 1 FYVE zinc finger IBR PF01485.21 AIN99471.1 - 0.22 11.8 3.5 0.59 10.4 3.5 1.6 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain DUF778 PF05608.12 AIN99472.1 - 5e-35 121.6 3.1 1.2e-19 71.5 0.1 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF778) DUF4796 PF16044.5 AIN99472.1 - 0.015 14.9 1.1 0.04 13.5 1.1 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4796) LRAT PF04970.13 AIN99472.1 - 0.065 13.5 0.1 0.089 13.1 0.1 1.2 1 0 0 1 1 1 0 Lecithin retinol acyltransferase Peptidase_C97 PF05903.14 AIN99472.1 - 0.17 11.7 0.3 0.27 11.1 0.3 1.3 1 0 0 1 1 1 0 PPPDE putative peptidase domain Pep3_Vps18 PF05131.14 AIN99473.1 - 8.1e-10 38.7 0.0 4.3e-08 33.1 0.0 3.1 2 1 0 2 2 2 1 Pep3/Vps18/deep orange family Clathrin PF00637.20 AIN99473.1 - 5.1e-08 32.9 0.1 2.4e-07 30.7 0.1 2.0 1 1 1 2 2 2 1 Region in Clathrin and VPS Vps39_2 PF10367.9 AIN99473.1 - 4e-05 24.0 0.2 8.4e-05 23.0 0.2 1.6 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 Zn_ribbon_17 PF17120.5 AIN99473.1 - 0.0012 18.4 2.5 0.0056 16.3 2.5 2.1 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type Clathrin_H_link PF13838.6 AIN99473.1 - 0.0086 16.0 0.0 0.046 13.6 0.0 2.2 2 0 0 2 2 2 1 Clathrin-H-link zf-RING_5 PF14634.6 AIN99473.1 - 0.037 14.0 3.1 0.12 12.4 3.1 2.0 1 0 0 1 1 1 0 zinc-RING finger domain zf-RING_UBOX PF13445.6 AIN99473.1 - 0.16 12.1 3.3 0.44 10.6 3.3 1.8 1 0 0 1 1 1 0 RING-type zinc-finger VPS11_C PF12451.8 AIN99473.1 - 0.22 11.7 0.4 0.49 10.7 0.4 1.6 1 0 0 1 1 1 0 Vacuolar protein sorting protein 11 C terminal CTU2 PF10288.9 AIN99473.1 - 0.4 10.9 1.5 0.51 10.6 0.2 1.8 2 0 0 2 2 2 0 Cytoplasmic tRNA 2-thiolation protein 2 DUF1295 PF06966.12 AIN99474.1 - 4.7e-29 101.6 10.9 1.7e-28 99.7 10.9 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF1295) H_PPase PF03030.16 AIN99474.1 - 0.88 8.1 4.2 3.7 6.1 0.6 2.0 2 0 0 2 2 2 0 Inorganic H+ pyrophosphatase Acyl-CoA_dh_1 PF00441.24 AIN99475.1 - 2.8e-40 137.9 1.8 2.9e-40 137.9 0.4 1.7 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 AIN99475.1 - 1.4e-28 99.8 0.0 4.1e-28 98.3 0.0 1.8 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 AIN99475.1 - 3.7e-24 84.7 0.1 7.3e-24 83.8 0.1 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 AIN99475.1 - 1.2e-19 70.9 0.1 2.7e-19 69.8 0.1 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_ox_N PF14749.6 AIN99475.1 - 0.14 12.8 0.0 0.24 12.0 0.0 1.4 1 0 0 1 1 1 0 Acyl-coenzyme A oxidase N-terminal XRN_N PF03159.18 AIN99476.1 - 6.2e-28 97.9 0.0 9.8e-28 97.2 0.0 1.2 1 0 0 1 1 1 1 XRN 5'-3' exonuclease N-terminus ABC2_membrane_3 PF12698.7 AIN99478.1 - 1.4e-63 215.1 58.4 1.7e-40 139.2 24.3 3.1 2 2 0 2 2 2 2 ABC-2 family transporter protein ABC_tran PF00005.27 AIN99478.1 - 1.4e-52 177.9 0.0 4.7e-27 95.2 0.0 2.5 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 AIN99478.1 - 6.2e-17 62.3 0.1 7.8e-06 25.9 0.0 4.2 4 0 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system DUF4162 PF13732.6 AIN99478.1 - 8.4e-05 23.2 0.0 0.18 12.6 0.2 2.7 2 0 0 2 2 2 2 Domain of unknown function (DUF4162) Zeta_toxin PF06414.12 AIN99478.1 - 0.00014 21.2 0.7 0.2 10.9 0.3 3.2 3 0 0 3 3 3 1 Zeta toxin SMC_N PF02463.19 AIN99478.1 - 0.00032 20.2 0.0 4.9 6.5 0.0 3.6 3 1 0 3 3 3 1 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 AIN99478.1 - 0.00042 20.3 0.0 0.022 14.7 0.0 2.4 2 0 0 2 2 2 1 RsgA GTPase AAA_29 PF13555.6 AIN99478.1 - 0.00067 19.4 0.4 0.18 11.6 0.1 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_30 PF13604.6 AIN99478.1 - 0.0013 18.5 0.0 0.074 12.8 0.0 2.4 2 0 0 2 2 2 1 AAA domain SbcCD_C PF13558.6 AIN99478.1 - 0.0019 18.4 0.0 2.5 8.4 0.0 4.1 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit SRP54 PF00448.22 AIN99478.1 - 0.0041 16.8 0.5 1.2 8.8 0.0 2.7 3 0 0 3 3 3 1 SRP54-type protein, GTPase domain AAA_23 PF13476.6 AIN99478.1 - 0.007 16.9 9.2 0.29 11.6 0.1 3.1 3 0 0 3 3 3 2 AAA domain AAA_15 PF13175.6 AIN99478.1 - 0.0097 15.6 1.8 2.9 7.5 0.0 3.7 4 0 0 4 4 4 1 AAA ATPase domain MMR_HSR1 PF01926.23 AIN99478.1 - 0.085 13.0 0.1 6.8 6.8 0.0 2.7 2 0 0 2 2 2 0 50S ribosome-binding GTPase RNA_helicase PF00910.22 AIN99478.1 - 0.085 13.2 0.2 22 5.5 0.0 2.6 2 0 0 2 2 2 0 RNA helicase AAA_16 PF13191.6 AIN99478.1 - 0.11 12.9 0.0 2.4 8.5 0.0 2.5 2 0 0 2 2 2 0 AAA ATPase domain MukB PF04310.12 AIN99478.1 - 0.16 11.8 0.9 4.5 7.0 0.1 2.4 2 0 0 2 2 2 0 MukB N-terminal AAA_22 PF13401.6 AIN99478.1 - 0.18 12.1 0.2 14 5.9 0.0 3.5 3 0 0 3 3 3 0 AAA domain AAA_27 PF13514.6 AIN99478.1 - 0.19 11.3 0.4 4.4 6.8 0.1 2.4 2 0 0 2 2 2 0 AAA domain ABC2_membrane PF01061.24 AIN99478.1 - 0.72 9.2 53.7 0.011 15.2 16.6 3.7 5 0 0 5 5 5 0 ABC-2 type transporter TatD_DNase PF01026.21 AIN99480.1 - 2.9e-37 128.4 0.0 3.6e-37 128.1 0.0 1.1 1 0 0 1 1 1 1 TatD related DNase Amidohydro_2 PF04909.14 AIN99480.1 - 1.8e-05 24.7 0.0 0.037 13.8 0.0 2.6 2 1 0 2 2 2 2 Amidohydrolase Sec6 PF06046.13 AIN99481.1 - 4.5e-11 41.8 0.2 8.6e-08 31.0 1.8 2.6 2 0 0 2 2 2 2 Exocyst complex component Sec6 DUF2894 PF11445.8 AIN99482.1 - 0.033 14.7 1.0 0.068 13.6 1.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2894) Pyridox_ox_2 PF12900.7 AIN99482.1 - 0.057 13.4 0.0 0.16 12.0 0.0 1.8 1 1 0 1 1 1 0 Pyridoxamine 5'-phosphate oxidase FAM117 PF15388.6 AIN99483.1 - 0.54 9.6 6.5 1.3 8.4 6.5 1.6 1 0 0 1 1 1 0 Protein Family FAM117 AAA PF00004.29 AIN99486.1 - 5.4e-87 289.0 0.0 1.3e-47 161.5 0.0 2.3 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 AIN99486.1 - 4.5e-24 84.0 1.5 6.5e-12 45.1 0.0 3.1 3 0 0 3 3 2 2 AAA+ lid domain RuvB_N PF05496.12 AIN99486.1 - 1.1e-15 57.8 0.0 8.5e-08 32.1 0.0 2.4 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 AIN99486.1 - 3.3e-13 50.4 0.7 0.00031 21.2 0.1 4.3 2 2 2 4 4 4 2 AAA ATPase domain AAA_5 PF07728.14 AIN99486.1 - 2.4e-11 43.8 0.0 0.00012 22.1 0.0 3.6 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 AIN99486.1 - 9.5e-11 42.1 0.0 2.4e-05 24.5 0.0 2.7 2 1 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 AIN99486.1 - 4e-09 36.9 0.3 0.013 15.8 0.0 4.2 2 2 0 2 2 2 2 AAA domain AAA_33 PF13671.6 AIN99486.1 - 7.1e-09 36.0 0.0 0.0018 18.5 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_14 PF13173.6 AIN99486.1 - 5.4e-07 29.7 0.0 0.026 14.5 0.0 2.4 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.22 AIN99486.1 - 1e-06 29.1 0.0 0.034 14.5 0.0 2.9 3 0 0 3 3 2 2 RNA helicase IstB_IS21 PF01695.17 AIN99486.1 - 4.6e-06 26.5 0.0 0.13 12.0 0.0 2.4 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_18 PF13238.6 AIN99486.1 - 8.1e-06 26.4 0.0 0.065 13.8 0.0 2.6 2 0 0 2 2 2 2 AAA domain TsaE PF02367.17 AIN99486.1 - 1.7e-05 24.8 0.0 0.28 11.2 0.0 2.3 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE TIP49 PF06068.13 AIN99486.1 - 1.8e-05 24.2 0.0 0.16 11.2 0.0 2.2 2 0 0 2 2 2 2 TIP49 P-loop domain Zeta_toxin PF06414.12 AIN99486.1 - 2.3e-05 23.8 0.0 0.021 14.1 0.0 2.7 2 0 0 2 2 2 2 Zeta toxin Mg_chelatase PF01078.21 AIN99486.1 - 4.7e-05 22.9 0.1 0.049 13.0 0.0 2.5 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 AIN99486.1 - 7.3e-05 22.6 0.0 0.51 10.2 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) NACHT PF05729.12 AIN99486.1 - 8.4e-05 22.6 0.1 0.38 10.7 0.0 3.0 3 0 0 3 3 3 2 NACHT domain AAA_24 PF13479.6 AIN99486.1 - 0.00012 21.9 0.0 0.49 10.1 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_28 PF13521.6 AIN99486.1 - 0.00016 21.9 0.0 0.37 11.0 0.0 2.5 2 0 0 2 2 2 2 AAA domain ABC_tran PF00005.27 AIN99486.1 - 0.0002 21.9 0.0 0.39 11.2 0.0 2.8 2 1 0 2 2 2 1 ABC transporter AAA_11 PF13086.6 AIN99486.1 - 0.00043 20.2 0.0 0.71 9.6 0.0 2.3 2 0 0 2 2 2 2 AAA domain Sigma54_activat PF00158.26 AIN99486.1 - 0.00044 20.0 0.0 0.093 12.4 0.0 2.8 3 0 0 3 3 2 1 Sigma-54 interaction domain AAA_17 PF13207.6 AIN99486.1 - 0.00082 19.8 0.2 0.33 11.4 0.0 3.0 3 1 0 3 3 2 1 AAA domain AAA_7 PF12775.7 AIN99486.1 - 0.0012 18.4 0.0 0.63 9.5 0.0 2.5 2 0 0 2 2 2 1 P-loop containing dynein motor region NB-ARC PF00931.22 AIN99486.1 - 0.0014 17.8 0.0 0.79 8.8 0.0 2.5 2 0 0 2 2 2 1 NB-ARC domain Vps4_C PF09336.10 AIN99486.1 - 0.0014 18.5 0.0 0.0057 16.6 0.0 2.0 2 0 0 2 2 1 1 Vps4 C terminal oligomerisation domain NTPase_1 PF03266.15 AIN99486.1 - 0.0015 18.5 0.1 0.24 11.3 0.0 2.8 2 0 0 2 2 2 1 NTPase ATPase_2 PF01637.18 AIN99486.1 - 0.0016 18.4 0.0 0.33 10.8 0.0 2.5 2 0 0 2 2 2 1 ATPase domain predominantly from Archaea Rad17 PF03215.15 AIN99486.1 - 0.0018 18.2 0.0 0.08 12.8 0.0 2.5 2 1 0 2 2 2 1 Rad17 P-loop domain AAA_25 PF13481.6 AIN99486.1 - 0.0019 17.8 1.6 2.2 7.8 0.1 3.6 2 2 1 3 3 3 1 AAA domain AAA_19 PF13245.6 AIN99486.1 - 0.0022 18.4 0.0 1.9 8.8 0.0 2.5 2 0 0 2 2 2 1 AAA domain Viral_helicase1 PF01443.18 AIN99486.1 - 0.0025 17.6 0.0 0.51 10.0 0.0 2.3 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase Bac_DnaA PF00308.18 AIN99486.1 - 0.0043 16.9 0.0 1.8 8.4 0.0 2.6 2 0 0 2 2 2 1 Bacterial dnaA protein Sigma54_activ_2 PF14532.6 AIN99486.1 - 0.0056 16.8 0.0 0.047 13.8 0.0 2.4 3 0 0 3 3 2 1 Sigma-54 interaction domain Parvo_NS1 PF01057.17 AIN99486.1 - 0.015 14.4 0.1 0.45 9.5 0.1 2.1 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 DUF815 PF05673.13 AIN99486.1 - 0.018 14.2 0.0 3.2 6.9 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_30 PF13604.6 AIN99486.1 - 0.03 14.1 0.1 10 5.8 0.0 2.8 3 0 0 3 3 2 0 AAA domain TniB PF05621.11 AIN99486.1 - 0.032 13.6 0.0 8.7 5.7 0.0 3.1 3 0 0 3 3 3 0 Bacterial TniB protein ATPase PF06745.13 AIN99486.1 - 0.12 11.7 0.0 3.1 7.1 0.0 2.4 2 1 0 2 2 2 0 KaiC Aminotran_5 PF00266.19 AIN99487.1 - 2.7e-80 270.1 0.0 3.1e-80 269.9 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 AIN99487.1 - 2e-08 33.9 0.0 3e-08 33.3 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.17 AIN99487.1 - 0.00029 20.2 0.0 0.00048 19.6 0.0 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Pyridoxal_deC PF00282.19 AIN99487.1 - 0.072 11.8 0.0 0.13 10.9 0.0 1.4 1 0 0 1 1 1 0 Pyridoxal-dependent decarboxylase conserved domain AAA PF00004.29 AIN99488.1 - 3e-37 128.0 0.0 4.5e-27 95.1 0.0 3.5 2 1 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 AIN99488.1 - 6.4e-12 45.9 1.6 0.00014 22.2 0.0 3.5 2 1 0 2 2 2 2 AAA domain AAA_16 PF13191.6 AIN99488.1 - 1.9e-09 38.1 3.5 0.0042 17.5 0.4 4.4 2 2 2 4 4 3 2 AAA ATPase domain Mg_chelatase PF01078.21 AIN99488.1 - 7.8e-08 32.0 0.0 0.00089 18.7 0.0 2.6 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_18 PF13238.6 AIN99488.1 - 2.5e-07 31.3 0.0 0.0021 18.6 0.0 3.0 2 0 0 2 2 2 2 AAA domain AAA_2 PF07724.14 AIN99488.1 - 2.9e-07 30.8 0.0 0.00034 20.8 0.0 2.4 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 AIN99488.1 - 3.5e-07 30.3 0.0 0.038 14.0 0.0 2.9 3 0 0 3 3 2 2 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.17 AIN99488.1 - 5.4e-07 29.5 0.0 0.00064 19.5 0.0 2.4 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_33 PF13671.6 AIN99488.1 - 9.6e-07 29.1 0.0 0.039 14.1 0.0 2.8 2 0 0 2 2 2 2 AAA domain ABC_tran PF00005.27 AIN99488.1 - 1.2e-06 29.1 0.0 0.0051 17.3 0.0 2.8 3 0 0 3 3 2 2 ABC transporter TIP49 PF06068.13 AIN99488.1 - 2.6e-06 26.9 0.0 0.034 13.3 0.0 2.2 2 0 0 2 2 2 2 TIP49 P-loop domain AAA_24 PF13479.6 AIN99488.1 - 2.8e-06 27.2 0.0 0.088 12.5 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_30 PF13604.6 AIN99488.1 - 5.3e-05 23.0 0.0 0.013 15.3 0.0 2.6 2 0 0 2 2 2 1 AAA domain RuvB_N PF05496.12 AIN99488.1 - 5.7e-05 22.9 0.0 0.13 12.0 0.0 2.5 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_28 PF13521.6 AIN99488.1 - 7.7e-05 23.0 1.4 0.031 14.5 0.0 3.2 3 0 0 3 3 3 1 AAA domain RNA_helicase PF00910.22 AIN99488.1 - 8.1e-05 23.0 0.0 0.48 10.8 0.0 2.5 2 0 0 2 2 2 2 RNA helicase AAA_lid_3 PF17862.1 AIN99488.1 - 8.4e-05 22.3 0.0 0.00024 20.9 0.0 1.8 1 0 0 1 1 1 1 AAA+ lid domain Sigma54_activat PF00158.26 AIN99488.1 - 0.00012 21.9 0.0 0.67 9.6 0.0 2.5 2 0 0 2 2 2 2 Sigma-54 interaction domain NACHT PF05729.12 AIN99488.1 - 0.00012 22.0 0.0 0.19 11.6 0.0 3.4 3 1 0 3 3 2 1 NACHT domain AAA_19 PF13245.6 AIN99488.1 - 0.00018 21.9 0.0 1.2 9.4 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_7 PF12775.7 AIN99488.1 - 0.00021 20.9 0.0 0.25 10.8 0.0 2.3 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA_17 PF13207.6 AIN99488.1 - 0.00025 21.5 0.0 0.3 11.5 0.0 2.5 2 0 0 2 2 2 1 AAA domain NB-ARC PF00931.22 AIN99488.1 - 0.00025 20.3 0.1 0.3 10.3 0.0 3.1 2 1 1 3 3 3 1 NB-ARC domain AAA_11 PF13086.6 AIN99488.1 - 0.00029 20.7 0.0 0.43 10.3 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.6 AIN99488.1 - 0.00066 19.4 0.1 0.16 11.7 0.1 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain Rad17 PF03215.15 AIN99488.1 - 0.00084 19.3 0.0 0.033 14.1 0.0 2.3 2 0 0 2 2 2 1 Rad17 P-loop domain DUF2075 PF09848.9 AIN99488.1 - 0.0013 18.1 0.0 0.16 11.1 0.0 2.3 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) AAA_14 PF13173.6 AIN99488.1 - 0.0013 18.7 0.0 0.14 12.2 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.6 AIN99488.1 - 0.0017 18.0 0.4 1.8 8.1 0.2 3.8 3 1 1 4 4 4 1 AAA domain NTPase_1 PF03266.15 AIN99488.1 - 0.0031 17.4 0.1 0.33 10.8 0.1 2.8 2 0 0 2 2 2 1 NTPase TsaE PF02367.17 AIN99488.1 - 0.0036 17.3 0.0 3.9 7.5 0.0 2.3 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE Sigma54_activ_2 PF14532.6 AIN99488.1 - 0.0036 17.4 0.0 0.99 9.5 0.0 2.5 2 0 0 2 2 2 1 Sigma-54 interaction domain TniB PF05621.11 AIN99488.1 - 0.0069 15.8 0.0 0.54 9.6 0.0 2.9 2 1 0 2 2 2 1 Bacterial TniB protein Adeno_IVa2 PF02456.15 AIN99488.1 - 0.018 13.8 0.0 4.2 6.1 0.0 2.1 2 0 0 2 2 2 0 Adenovirus IVa2 protein ATPase_2 PF01637.18 AIN99488.1 - 0.035 14.0 0.0 4.1 7.2 0.0 2.4 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea Cytidylate_kin PF02224.18 AIN99488.1 - 0.037 13.8 0.0 0.29 10.8 0.0 2.4 2 1 1 3 3 3 0 Cytidylate kinase MMR_HSR1 PF01926.23 AIN99488.1 - 0.045 13.8 0.0 0.22 11.6 0.0 2.1 2 0 0 2 2 2 0 50S ribosome-binding GTPase KTI12 PF08433.10 AIN99488.1 - 0.074 12.5 0.0 11 5.3 0.0 2.3 2 0 0 2 2 2 0 Chromatin associated protein KTI12 PhoH PF02562.16 AIN99488.1 - 0.1 12.0 0.0 8.1 5.8 0.1 2.3 2 0 0 2 2 2 0 PhoH-like protein T2SSE PF00437.20 AIN99488.1 - 0.11 11.6 0.1 0.98 8.4 0.2 2.1 2 0 0 2 2 2 0 Type II/IV secretion system protein Parvo_NS1 PF01057.17 AIN99488.1 - 0.11 11.6 0.0 5.1 6.1 0.0 2.2 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 PPV_E1_C PF00519.17 AIN99488.1 - 0.2 10.5 0.0 12 4.6 0.0 2.2 2 0 0 2 2 2 0 Papillomavirus helicase AAA_23 PF13476.6 AIN99488.1 - 0.21 12.1 0.0 2.8 8.4 0.0 2.3 2 0 0 2 2 2 0 AAA domain TPR_14 PF13428.6 AIN99489.1 - 2e-11 43.7 43.7 0.19 12.6 0.0 16.0 12 6 5 17 17 17 3 Tetratricopeptide repeat TPR_1 PF00515.28 AIN99489.1 - 1.9e-07 30.6 2.1 0.71 9.8 0.1 8.0 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_17 PF13431.6 AIN99489.1 - 2.1e-07 30.8 14.0 0.87 10.1 0.0 8.9 9 0 0 9 9 9 2 Tetratricopeptide repeat TPR_2 PF07719.17 AIN99489.1 - 9.9e-07 28.4 18.6 40 4.7 0.4 12.2 13 0 0 13 13 13 0 Tetratricopeptide repeat TPR_7 PF13176.6 AIN99489.1 - 1.2e-05 25.0 9.9 3.8 7.8 0.2 7.8 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_11 PF13414.6 AIN99489.1 - 0.00018 21.1 1.4 8.4 6.2 0.3 6.0 8 0 0 8 8 8 2 TPR repeat TPR_12 PF13424.6 AIN99489.1 - 0.00021 21.5 40.9 0.23 11.8 3.3 11.0 9 1 1 10 10 10 2 Tetratricopeptide repeat TPR_19 PF14559.6 AIN99489.1 - 0.0012 19.3 23.8 1.4 9.5 0.0 9.4 10 0 0 10 10 10 2 Tetratricopeptide repeat TPR_8 PF13181.6 AIN99489.1 - 0.005 17.0 12.3 20 5.7 0.0 8.5 10 0 0 10 10 10 0 Tetratricopeptide repeat TPR_16 PF13432.6 AIN99489.1 - 0.037 14.7 0.2 0.037 14.7 0.2 10.4 10 1 1 11 11 11 0 Tetratricopeptide repeat EBP PF05241.12 AIN99490.1 - 2.8e-11 43.2 7.5 3.6e-11 42.9 7.5 1.1 1 0 0 1 1 1 1 Emopamil binding protein DUF2781 PF10914.8 AIN99490.1 - 8.5e-05 23.0 10.6 0.00011 22.7 10.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2781) MRP PF09387.10 AIN99492.1 - 9.5e-46 156.3 0.4 9.5e-46 156.3 0.4 1.7 2 0 0 2 2 2 1 Mitochondrial RNA binding protein MRP WGG PF10273.9 AIN99493.1 - 0.0001 22.9 0.8 0.00024 21.7 0.8 1.6 1 1 0 1 1 1 1 Pre-rRNA-processing protein TSR2 Glyco_transf_43 PF03360.16 AIN99493.1 - 0.0075 16.1 0.0 0.011 15.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 43 DUF5435 PF17503.2 AIN99493.1 - 0.026 14.2 0.0 0.039 13.7 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5435) Virul_Fac PF10139.9 AIN99493.1 - 0.06 11.6 0.0 0.071 11.3 0.0 1.0 1 0 0 1 1 1 0 Putative bacterial virulence factor TPR_16 PF13432.6 AIN99495.1 - 8.4e-28 96.7 20.0 1.1e-05 25.9 0.3 7.4 6 1 3 9 9 8 6 Tetratricopeptide repeat TPR_1 PF00515.28 AIN99495.1 - 9.6e-23 79.0 44.6 6.5e-05 22.6 0.9 11.6 12 0 0 12 12 11 5 Tetratricopeptide repeat TPR_2 PF07719.17 AIN99495.1 - 1.1e-22 78.3 45.7 0.0011 18.9 0.3 11.9 12 0 0 12 12 11 6 Tetratricopeptide repeat TPR_19 PF14559.6 AIN99495.1 - 5.6e-20 71.6 24.2 2e-05 25.0 1.2 7.4 6 2 3 9 9 8 5 Tetratricopeptide repeat TPR_6 PF13174.6 AIN99495.1 - 2.6e-17 62.2 28.0 0.00021 21.7 0.0 10.8 12 0 0 12 12 11 4 Tetratricopeptide repeat TPR_7 PF13176.6 AIN99495.1 - 1.8e-16 58.9 25.1 0.038 14.0 0.0 10.0 11 0 0 11 11 10 4 Tetratricopeptide repeat TPR_12 PF13424.6 AIN99495.1 - 9.3e-16 57.9 33.0 0.0001 22.5 0.2 9.0 7 4 1 9 9 9 5 Tetratricopeptide repeat TPR_8 PF13181.6 AIN99495.1 - 1.1e-15 56.4 30.8 0.0086 16.2 0.4 10.2 12 0 0 12 12 9 5 Tetratricopeptide repeat TPR_14 PF13428.6 AIN99495.1 - 6e-12 45.3 14.8 0.042 14.7 0.0 9.5 5 3 6 11 11 10 3 Tetratricopeptide repeat TPR_11 PF13414.6 AIN99495.1 - 3.9e-10 39.2 22.8 3.7e-06 26.5 1.3 7.3 9 1 0 9 9 7 3 TPR repeat ANAPC3 PF12895.7 AIN99495.1 - 9e-10 38.7 29.4 0.00067 19.8 0.3 7.3 5 2 4 9 9 9 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.6 AIN99495.1 - 1.2e-06 28.6 5.5 0.018 15.1 0.0 5.7 4 2 1 5 5 5 1 Tetratricopeptide repeat DUF3808 PF10300.9 AIN99495.1 - 3.6e-05 22.7 1.9 0.00088 18.1 0.1 2.7 2 1 0 2 2 2 1 Protein of unknown function (DUF3808) TPR_17 PF13431.6 AIN99495.1 - 4.8e-05 23.5 29.7 0.01 16.1 0.5 9.4 10 0 0 10 10 10 1 Tetratricopeptide repeat TPR_4 PF07721.14 AIN99495.1 - 0.00016 22.0 0.9 15 6.6 0.1 5.2 5 0 0 5 5 4 0 Tetratricopeptide repeat DUF4919 PF16266.5 AIN99495.1 - 0.00083 19.3 3.7 0.13 12.2 0.0 3.1 3 0 0 3 3 3 1 Domain of unknown function (DUF4919) PPR PF01535.20 AIN99495.1 - 0.0019 18.4 13.4 2.8 8.4 0.0 7.4 9 0 0 9 9 6 2 PPR repeat TPR_21 PF09976.9 AIN99495.1 - 0.0068 16.1 2.9 0.0068 16.1 2.9 2.8 3 0 0 3 3 2 1 Tetratricopeptide repeat-like domain 23S_rRNA_IVP PF05635.11 AIN99495.1 - 0.15 12.3 3.1 5.3 7.4 0.1 4.0 4 0 0 4 4 4 0 23S rRNA-intervening sequence protein DUF2989 PF11207.8 AIN99495.1 - 0.23 11.2 8.6 0.11 12.2 2.2 3.3 2 2 2 4 4 4 0 Protein of unknown function (DUF2989) DUF3856 PF12968.7 AIN99495.1 - 0.66 10.0 4.6 7.8 6.6 0.3 3.6 3 2 0 3 3 3 0 Domain of Unknown Function (DUF3856) DUF2225 PF09986.9 AIN99495.1 - 1 9.1 24.0 1.3 8.7 6.1 5.6 2 2 2 4 4 4 0 Uncharacterized protein conserved in bacteria (DUF2225) DUF3837 PF12939.7 AIN99495.1 - 1.1 9.7 5.9 2.9 8.3 0.1 4.0 5 0 0 5 5 3 0 Domain of unknown function (DUF3837) Sel1 PF08238.12 AIN99495.1 - 1.5 9.6 18.5 5.6 7.8 0.1 7.2 7 1 1 8 8 6 0 Sel1 repeat TPR_10 PF13374.6 AIN99495.1 - 1.6 8.7 32.2 17 5.5 0.1 9.0 11 0 0 11 11 9 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 AIN99495.1 - 5.3 7.2 24.7 1.8 8.7 0.2 6.5 7 1 1 8 8 6 0 Fis1 C-terminal tetratricopeptide repeat JmjC PF02373.22 AIN99497.1 - 1.2e-10 41.8 4.8 5.8e-09 36.4 4.8 2.4 1 1 0 1 1 1 1 JmjC domain, hydroxylase Cupin_8 PF13621.6 AIN99497.1 - 0.00034 20.4 0.0 0.023 14.4 0.0 2.7 2 1 0 2 2 2 2 Cupin-like domain RAI16-like PF10257.9 AIN99498.1 - 7.7e-09 34.9 1.4 0.00014 20.8 0.0 3.5 2 1 1 3 3 3 3 Retinoic acid induced 16-like protein eIF-1a PF01176.19 AIN99499.1 - 0.039 13.7 0.0 0.1 12.4 0.0 1.6 2 0 0 2 2 2 0 Translation initiation factor 1A / IF-1 SpoIIE PF07228.12 AIN99500.1 - 0.00011 22.1 3.6 0.081 12.8 2.7 3.0 1 1 1 2 2 2 2 Stage II sporulation protein E (SpoIIE) YbgS PF13985.6 AIN99500.1 - 0.06 13.6 6.2 0.13 12.6 6.2 1.4 1 0 0 1 1 1 0 YbgS-like protein zf-RING_2 PF13639.6 AIN99501.1 - 4.1e-08 33.4 15.2 7.1e-08 32.7 15.2 1.4 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 AIN99501.1 - 6.2e-08 32.8 10.8 1.3e-07 31.8 10.8 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 AIN99501.1 - 1.5e-05 25.0 5.7 3.3e-05 23.8 5.7 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_2 PF13923.6 AIN99501.1 - 6.3e-05 22.7 12.6 0.00011 22.0 12.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 AIN99501.1 - 0.00011 22.1 8.8 0.00023 21.1 8.8 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_11 PF17123.5 AIN99501.1 - 0.00017 21.3 10.0 0.00033 20.3 10.0 1.5 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4 PF00097.25 AIN99501.1 - 0.0025 17.6 11.3 0.0046 16.8 11.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 AIN99501.1 - 0.021 14.8 12.5 0.035 14.1 12.5 1.4 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4_3 PF13920.6 AIN99501.1 - 0.15 12.0 10.8 0.25 11.2 10.8 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 AIN99501.1 - 3 7.5 9.2 5.6 6.7 9.2 1.4 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type IF-2B PF01008.17 AIN99502.1 - 9.1e-34 116.9 0.0 1.7e-33 116.1 0.0 1.5 1 0 0 1 1 1 1 Initiation factor 2 subunit family Secretin_N_2 PF07655.13 AIN99503.1 - 0.26 11.9 1.6 0.74 10.4 0.2 2.2 2 0 0 2 2 2 0 Secretin N-terminal domain HC2 PF07382.11 AIN99505.1 - 0.0014 18.8 71.1 0.0017 18.5 71.1 1.2 1 0 0 1 1 1 1 Histone H1-like nucleoprotein HC2 WD40 PF00400.32 AIN99506.1 - 1.3e-16 60.6 15.3 0.00088 20.1 0.4 5.7 4 1 1 5 5 5 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 AIN99506.1 - 0.00017 21.8 0.1 0.54 10.6 0.0 3.7 2 2 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Cpn60_TCP1 PF00118.24 AIN99507.1 - 1.8e-147 491.9 12.6 2.1e-147 491.7 12.6 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family DUF5442 PF17514.2 AIN99507.1 - 0.16 12.2 0.5 0.54 10.5 0.2 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF5442) Cation_efflux PF01545.21 AIN99508.1 - 8.6e-43 146.4 14.1 8.6e-43 146.4 14.1 2.6 2 0 0 2 2 2 1 Cation efflux family UCH PF00443.29 AIN99509.1 - 2e-49 168.4 1.4 3e-49 167.8 1.4 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 AIN99509.1 - 2.3e-15 57.0 5.1 2.3e-15 57.0 5.1 2.1 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase DZR PF12773.7 AIN99509.1 - 0.035 14.1 6.7 0.25 11.4 6.7 2.2 1 1 0 1 1 1 0 Double zinc ribbon PhnA_Zn_Ribbon PF08274.12 AIN99509.1 - 0.48 10.4 5.3 3 7.9 0.3 2.5 2 0 0 2 2 2 0 PhnA Zinc-Ribbon Zn-ribbon_8 PF09723.10 AIN99509.1 - 0.7 10.1 3.5 14 5.9 0.2 2.6 2 0 0 2 2 2 0 Zinc ribbon domain zf-CHY PF05495.12 AIN99509.1 - 1.1 9.8 6.5 14 6.3 0.8 2.8 1 1 1 2 2 2 0 CHY zinc finger zinc-ribbons_6 PF07191.12 AIN99509.1 - 1.4 8.9 5.7 4.2 7.4 4.3 2.4 1 1 1 2 2 2 0 zinc-ribbons zf-ribbon_3 PF13248.6 AIN99509.1 - 1.8 8.1 4.3 8.1 6.0 0.5 2.4 2 0 0 2 2 2 0 zinc-ribbon domain zinc_ribbon_10 PF10058.9 AIN99509.1 - 4.4 7.1 7.3 5.1 6.9 0.3 3.0 3 0 0 3 3 3 0 Predicted integral membrane zinc-ribbon metal-binding protein Ribonucleas_3_3 PF14622.6 AIN99511.1 - 9.7e-06 25.8 0.0 0.00012 22.3 0.0 2.0 1 1 0 1 1 1 1 Ribonuclease-III-like LRR_6 PF13516.6 AIN99512.1 - 1.9e-16 58.7 19.9 0.0032 17.4 0.0 9.5 9 0 0 9 9 9 7 Leucine Rich repeat LRR_1 PF00560.33 AIN99512.1 - 1.1e-08 34.4 1.3 3.7 8.5 0.4 7.5 8 1 0 8 8 8 1 Leucine Rich Repeat LRR_8 PF13855.6 AIN99512.1 - 6.6e-06 25.8 1.7 0.023 14.5 0.8 5.3 4 2 0 4 4 4 1 Leucine rich repeat LRR_4 PF12799.7 AIN99512.1 - 7.5e-06 26.2 5.0 0.24 11.9 0.2 5.3 5 1 1 6 6 6 3 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 AIN99512.1 - 0.12 11.9 0.0 0.55 9.7 0.0 2.1 2 0 0 2 2 2 0 Leucine-rich repeat KH_1 PF00013.29 AIN99513.1 - 1.1e-07 31.6 0.0 2.5e-07 30.4 0.0 1.6 1 0 0 1 1 1 1 KH domain zf-CCCH_4 PF18044.1 AIN99513.1 - 2.5e-06 27.2 5.1 5e-06 26.2 5.1 1.6 1 0 0 1 1 1 1 CCCH-type zinc finger Helicase_C PF00271.31 AIN99513.1 - 0.00016 22.0 0.2 0.00065 20.0 0.3 2.0 2 1 0 2 2 2 1 Helicase conserved C-terminal domain zf-CCCH PF00642.24 AIN99513.1 - 0.00097 19.0 3.8 0.0029 17.5 3.8 1.8 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 AIN99513.1 - 0.0091 16.0 2.0 0.022 14.8 2.0 1.7 1 0 0 1 1 1 1 Zinc finger domain tRNA-synt_1d PF00750.19 AIN99514.1 - 1.7e-110 369.2 0.3 9.7e-66 222.1 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class I (R) DALR_1 PF05746.15 AIN99514.1 - 7.8e-27 93.8 3.5 6.1e-26 90.9 0.8 2.8 2 0 0 2 2 2 1 DALR anticodon binding domain Arg_tRNA_synt_N PF03485.16 AIN99514.1 - 5.1e-14 52.6 0.4 2.3e-13 50.6 0.4 2.2 1 0 0 1 1 1 1 Arginyl tRNA synthetase N terminal domain Cupin_8 PF13621.6 AIN99515.1 - 7.7e-18 65.1 1.1 5.1e-17 62.4 0.1 2.6 1 1 1 2 2 2 1 Cupin-like domain JmjC PF02373.22 AIN99515.1 - 9.4e-12 45.4 0.1 2.1e-11 44.3 0.1 1.6 1 0 0 1 1 1 1 JmjC domain, hydroxylase Cupin_4 PF08007.12 AIN99515.1 - 1.8e-05 24.4 0.0 3.3e-05 23.5 0.0 1.5 1 1 0 1 1 1 1 Cupin superfamily protein F-box PF00646.33 AIN99515.1 - 0.00067 19.5 0.4 0.0027 17.6 0.3 1.9 2 0 0 2 2 2 1 F-box domain Cupin_2 PF07883.11 AIN99515.1 - 0.014 15.1 0.0 0.041 13.6 0.0 1.7 1 0 0 1 1 1 0 Cupin domain F-box-like PF12937.7 AIN99515.1 - 0.062 13.2 0.6 0.15 11.9 0.6 1.6 1 0 0 1 1 1 0 F-box-like MAGE_N PF12440.8 AIN99515.1 - 7.5 7.3 9.3 17 6.1 0.2 2.5 2 0 0 2 2 2 0 Melanoma associated antigen family N terminal Ferritin-like PF12902.7 AIN99519.1 - 1.6 8.5 13.6 0.2 11.5 8.2 2.2 1 1 1 2 2 2 0 Ferritin-like Pkinase PF00069.25 AIN99520.1 - 3e-60 203.8 0.0 4.3e-60 203.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 AIN99520.1 - 2.6e-42 144.9 0.0 4.1e-42 144.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 AIN99520.1 - 0.004 17.1 0.0 0.016 15.1 0.0 2.0 1 1 1 2 2 2 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 AIN99520.1 - 0.029 13.2 1.5 0.11 11.3 0.0 2.3 3 0 0 3 3 3 0 Fungal protein kinase RIO1 PF01163.22 AIN99520.1 - 0.098 12.2 0.0 0.43 10.2 0.0 1.9 1 1 1 2 2 2 0 RIO1 family Kinase-like PF14531.6 AIN99520.1 - 0.18 11.1 0.0 0.76 9.0 0.0 1.7 2 0 0 2 2 2 0 Kinase-like RL10P_insert PF17777.1 AIN99521.1 - 1.4e-20 73.0 0.2 2.5e-20 72.2 0.2 1.4 1 0 0 1 1 1 1 Insertion domain in 60S ribosomal protein L10P Ribosomal_L10 PF00466.20 AIN99521.1 - 8.7e-18 64.3 0.1 2.1e-17 63.1 0.1 1.6 1 0 0 1 1 1 1 Ribosomal protein L10 Ribosomal_60s PF00428.19 AIN99521.1 - 8.3e-12 45.5 6.4 8.3e-12 45.5 6.4 2.2 2 0 0 2 2 2 1 60s Acidic ribosomal protein DUF3479 PF11965.8 AIN99521.1 - 0.091 12.9 0.0 0.15 12.2 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3479) DUF1719 PF08224.11 AIN99522.1 - 0.017 14.3 0.0 0.02 14.0 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1719) Choline_kinase PF01633.20 AIN99524.1 - 1.5e-21 77.0 0.3 2.4e-20 73.0 0.3 2.1 1 1 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.23 AIN99524.1 - 2.6e-10 40.6 0.2 1.2e-09 38.5 0.2 2.1 1 1 0 1 1 1 1 Phosphotransferase enzyme family Pkinase PF00069.25 AIN99524.1 - 0.013 14.9 0.0 0.024 14.0 0.0 1.4 1 0 0 1 1 1 0 Protein kinase domain AlbA_2 PF04326.14 AIN99525.1 - 0.00042 20.6 0.0 0.00076 19.8 0.0 1.4 1 0 0 1 1 1 1 Putative DNA-binding domain Snf7 PF03357.21 AIN99526.1 - 1.3e-32 112.8 32.9 1.3e-32 112.8 32.9 1.4 1 1 1 2 2 2 1 Snf7 Arg_decarbox_C PF17944.1 AIN99526.1 - 1.2 9.7 6.0 7.5 7.2 0.6 3.4 3 1 1 4 4 4 0 Arginine decarboxylase C-terminal helical extension CBF PF03914.17 AIN99527.1 - 2.1e-32 112.5 1.8 2.1e-32 112.5 1.8 2.0 2 0 0 2 2 2 1 CBF/Mak21 family DUF2773 PF10971.8 AIN99527.1 - 0.11 12.6 0.0 0.23 11.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2773) PCI PF01399.27 AIN99528.1 - 1.8e-18 66.9 0.1 3.5e-18 66.0 0.1 1.5 1 0 0 1 1 1 1 PCI domain Rpn3_C PF08375.11 AIN99528.1 - 1.5e-15 57.3 0.9 1.5e-15 57.3 0.9 2.0 3 0 0 3 3 3 1 Proteasome regulatory subunit C-terminal TPR_2 PF07719.17 AIN99528.1 - 0.075 13.2 0.8 0.22 11.7 0.8 1.9 1 0 0 1 1 1 0 Tetratricopeptide repeat cNMP_binding PF00027.29 AIN99529.1 - 8.7e-14 51.4 0.6 0.0002 21.4 0.0 4.4 3 2 1 4 4 4 3 Cyclic nucleotide-binding domain SPX PF03105.19 AIN99530.1 - 0.0073 16.3 2.0 0.014 15.4 2.0 1.4 1 0 0 1 1 1 1 SPX domain Spatacsin_C PF14649.6 AIN99530.1 - 0.17 11.0 0.7 0.24 10.5 0.7 1.2 1 0 0 1 1 1 0 Spatacsin C-terminus DUF3093 PF11292.8 AIN99532.1 - 0.052 13.8 5.2 1.3 9.2 0.5 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3093) AroM PF07302.11 AIN99533.1 - 0.002 17.6 0.1 0.0042 16.5 0.1 1.5 1 0 0 1 1 1 1 AroM protein DUF543 PF04418.12 AIN99534.1 - 4.3e-22 77.9 0.0 5.7e-22 77.5 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF543) TctA PF01970.16 AIN99534.1 - 0.044 12.5 0.1 0.093 11.4 0.0 1.5 1 1 1 2 2 2 0 Tripartite tricarboxylate transporter TctA family RNA_pol_L_2 PF13656.6 AIN99535.1 - 2.5e-22 78.5 0.0 3.3e-22 78.0 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.24 AIN99535.1 - 2.1e-05 23.9 0.0 4.3e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain DAGAT PF03982.13 AIN99536.1 - 7.9e-34 116.9 0.0 1.3e-33 116.2 0.0 1.2 1 0 0 1 1 1 1 Diacylglycerol acyltransferase Aa_trans PF01490.18 AIN99538.1 - 1.4e-58 198.6 28.0 1.6e-58 198.4 28.0 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 AIN99538.1 - 1.3e-10 40.9 7.1 1.3e-10 40.9 7.1 1.6 2 0 0 2 2 2 1 Tryptophan/tyrosine permease family DUF4231 PF14015.6 AIN99538.1 - 0.55 10.7 9.4 4.1 7.9 0.3 3.8 3 1 1 4 4 4 0 Protein of unknown function (DUF4231) HC2 PF07382.11 AIN99540.1 - 0.13 12.4 41.6 0.14 12.3 41.6 1.0 1 0 0 1 1 1 0 Histone H1-like nucleoprotein HC2 IF4E PF01652.18 AIN99541.1 - 1e-44 152.2 0.4 1.2e-44 152.0 0.4 1.0 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E WD40 PF00400.32 AIN99542.1 - 1.6e-06 28.7 3.8 11 7.1 0.1 6.3 6 1 0 6 6 6 4 WD domain, G-beta repeat eIF2A PF08662.11 AIN99542.1 - 0.068 13.0 0.0 2 8.3 0.0 2.8 3 0 0 3 3 3 0 Eukaryotic translation initiation factor eIF2A BRO1 PF03097.18 AIN99543.1 - 7.3e-59 199.5 1.0 7.3e-59 199.5 1.0 2.3 2 0 0 2 2 2 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.6 AIN99543.1 - 6.7e-30 104.4 8.9 6.7e-30 104.4 8.9 2.5 1 1 1 2 2 2 1 ALIX V-shaped domain binding to HIV DHHA2 PF02833.14 AIN99543.1 - 0.088 13.0 1.3 30 4.8 0.1 3.9 4 0 0 4 4 4 0 DHHA2 domain MIT PF04212.18 AIN99543.1 - 0.093 12.8 0.0 0.093 12.8 0.0 3.9 5 0 0 5 5 5 0 MIT (microtubule interacting and transport) domain TPR_1 PF00515.28 AIN99543.1 - 0.1 12.5 0.9 0.32 10.9 0.1 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF3964 PF13107.6 AIN99543.1 - 0.14 12.6 0.0 0.37 11.2 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3964) Cob_adeno_trans PF01923.18 AIN99543.1 - 0.98 9.5 8.7 0.066 13.4 0.5 3.2 3 1 0 3 3 3 0 Cobalamin adenosyltransferase Strumpellin PF10266.9 AIN99545.1 - 0 1304.5 0.0 0 1304.3 0.0 1.0 1 0 0 1 1 1 1 Hereditary spastic paraplegia protein strumpellin ThiF PF00899.21 AIN99546.1 - 3.4e-62 210.0 0.0 6.3e-62 209.1 0.0 1.3 1 0 0 1 1 1 1 ThiF family Rhodanese PF00581.20 AIN99546.1 - 2.6e-05 24.7 0.0 0.00012 22.5 0.0 2.0 2 0 0 2 2 2 1 Rhodanese-like domain Sacchrp_dh_NADP PF03435.18 AIN99546.1 - 0.0014 18.9 0.3 0.0032 17.7 0.3 1.6 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain OAM_alpha PF16552.5 AIN99546.1 - 0.019 14.8 0.0 0.039 13.8 0.0 1.5 1 0 0 1 1 1 0 D-ornithine 4,5-aminomutase alpha-subunit Shikimate_DH PF01488.20 AIN99546.1 - 0.025 14.6 0.1 0.13 12.3 0.1 2.0 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Pea-VEAacid PF08111.11 AIN99546.1 - 0.037 14.3 0.0 0.092 13.1 0.0 1.7 1 0 0 1 1 1 0 Pea-VEAacid family 3HCDH_N PF02737.18 AIN99546.1 - 0.08 12.8 0.0 0.16 11.8 0.0 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.14 AIN99546.1 - 0.13 11.8 0.1 0.22 11.1 0.1 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain LRR_9 PF14580.6 AIN99547.1 - 0.003 17.1 0.0 0.0061 16.1 0.0 1.5 1 0 0 1 1 1 1 Leucine-rich repeat LRR_4 PF12799.7 AIN99548.1 - 0.00025 21.4 0.3 0.00064 20.1 0.3 1.7 1 0 0 1 1 1 1 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 AIN99548.1 - 0.0026 17.5 2.0 0.01 15.6 2.0 2.0 1 1 0 1 1 1 1 Leucine rich repeat LRR_9 PF14580.6 AIN99548.1 - 0.0058 16.2 0.0 0.012 15.1 0.0 1.5 1 0 0 1 1 1 1 Leucine-rich repeat zf_CCCH_4 PF18345.1 AIN99548.1 - 0.016 15.2 1.1 0.1 12.7 1.1 2.3 1 1 0 1 1 1 0 Zinc finger domain zf-CCCH PF00642.24 AIN99548.1 - 0.045 13.7 2.4 0.085 12.8 2.4 1.4 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.6 AIN99548.1 - 0.046 14.2 3.1 0.1 13.1 3.1 1.6 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger LRR_6 PF13516.6 AIN99548.1 - 0.052 13.6 0.3 2.5 8.4 0.1 2.8 2 0 0 2 2 2 0 Leucine Rich repeat zf-CCCH_4 PF18044.1 AIN99548.1 - 0.16 11.8 2.0 0.43 10.4 2.0 1.8 1 0 0 1 1 1 0 CCCH-type zinc finger ABC2_membrane PF01061.24 AIN99549.1 - 0.00088 18.8 14.5 0.00088 18.8 14.5 2.0 2 0 0 2 2 2 1 ABC-2 type transporter HpaP PF09483.10 AIN99549.1 - 0.12 12.6 0.4 5 7.4 0.0 2.4 2 0 0 2 2 2 0 Type III secretion protein (HpaP) ABC_tran PF00005.27 AIN99549.1 - 0.14 12.6 0.0 0.27 11.7 0.0 1.4 1 0 0 1 1 1 0 ABC transporter Metal_resist PF13801.6 AIN99549.1 - 1 9.6 4.8 0.35 11.1 0.9 2.3 2 0 0 2 2 2 0 Heavy-metal resistance eRF1_2 PF03464.15 AIN99550.1 - 2.4e-41 141.2 0.0 4.5e-41 140.3 0.0 1.5 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.15 AIN99550.1 - 6.6e-37 126.5 1.5 1.1e-36 125.7 0.3 2.0 2 0 0 2 2 2 1 eRF1 domain 3 eRF1_1 PF03463.15 AIN99550.1 - 2e-12 47.3 0.0 3.3e-12 46.5 0.0 1.4 1 0 0 1 1 1 1 eRF1 domain 1 acVLRF1 PF18859.1 AIN99550.1 - 6.1e-09 36.3 0.0 9.5e-09 35.6 0.0 1.3 1 0 0 1 1 1 1 Actinobacteria/chloroflexi VLRF1 release factor baeRF_family10 PF18854.1 AIN99550.1 - 8e-09 35.9 0.0 1.4e-08 35.1 0.0 1.4 1 0 0 1 1 1 1 Bacterial archaeo-eukaryotic release factor family 10 Vps5 PF09325.10 AIN99551.1 - 0.015 14.9 8.9 0.15 11.6 8.9 2.2 1 1 0 1 1 1 0 Vps5 C terminal like HlyD_2 PF12700.7 AIN99551.1 - 0.018 13.8 5.6 0.027 13.2 5.6 1.2 1 0 0 1 1 1 0 HlyD family secretion protein Fer2_3 PF13085.6 AIN99551.1 - 0.056 13.4 0.3 0.14 12.2 0.3 1.7 1 1 0 1 1 1 0 2Fe-2S iron-sulfur cluster binding domain Big_10 PF17964.1 AIN99551.1 - 0.074 13.0 2.1 0.13 12.2 2.1 1.4 1 0 0 1 1 1 0 Bacterial Ig domain DUF2280 PF10045.9 AIN99551.1 - 0.078 13.3 0.2 2.6 8.4 0.0 2.9 2 1 0 3 3 3 0 Uncharacterized conserved protein (DUF2280) RHD3 PF05879.12 AIN99551.1 - 0.16 10.1 6.8 0.2 9.7 6.8 1.0 1 0 0 1 1 1 0 Root hair defective 3 GTP-binding protein (RHD3) ALMT PF11744.8 AIN99551.1 - 0.73 8.6 5.6 0.51 9.1 3.9 1.5 1 1 0 1 1 1 0 Aluminium activated malate transporter STAT_alpha PF01017.20 AIN99551.1 - 1.3 8.9 5.2 1.1 9.1 3.3 1.9 2 0 0 2 2 2 0 STAT protein, all-alpha domain DUF2203 PF09969.9 AIN99551.1 - 1.3 9.7 6.3 1.1 10.0 2.5 2.5 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2203) OmpH PF03938.14 AIN99551.1 - 2.5 8.4 11.3 14 6.1 6.1 2.9 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) AAA_6 PF12774.7 AIN99552.1 - 1.8e-124 415.0 0.0 3.3e-124 414.1 0.0 1.5 1 0 0 1 1 1 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 AIN99552.1 - 2e-109 366.3 2.8 2e-109 366.3 2.8 4.4 4 0 0 4 4 4 1 Dynein heavy chain, N-terminal region 2 AAA_9 PF12781.7 AIN99552.1 - 3e-60 203.1 1.8 3e-60 203.1 1.8 2.5 2 0 0 2 2 1 1 ATP-binding dynein motor region AAA_8 PF12780.7 AIN99552.1 - 1.6e-47 162.1 0.1 2.9e-46 157.9 0.0 2.7 2 0 0 2 2 2 1 P-loop containing dynein motor region D4 AAA_lid_11 PF18198.1 AIN99552.1 - 8.2e-31 107.0 0.0 2.5e-30 105.5 0.0 1.9 2 0 0 2 2 1 1 Dynein heavy chain AAA lid domain AAA_5 PF07728.14 AIN99552.1 - 1.1e-30 106.4 0.0 3.6e-19 69.1 0.0 5.7 4 1 0 4 4 4 3 AAA domain (dynein-related subfamily) AAA_7 PF12775.7 AIN99552.1 - 1.5e-30 106.0 0.0 2.4e-24 85.8 0.0 4.4 4 0 0 4 4 4 2 P-loop containing dynein motor region Dynein_heavy PF03028.15 AIN99552.1 - 9.6e-26 90.2 0.0 7.4e-25 87.4 0.0 2.7 2 0 0 2 2 1 1 Dynein heavy chain region D6 P-loop domain MT PF12777.7 AIN99552.1 - 1.1e-24 87.1 5.8 2.2e-24 86.2 5.8 1.5 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor Dynein_C PF18199.1 AIN99552.1 - 9.9e-22 77.5 0.0 9.9e-22 77.5 0.0 2.3 3 0 0 3 3 2 1 Dynein heavy chain C-terminal domain AAA_16 PF13191.6 AIN99552.1 - 3e-15 57.0 4.1 0.00067 20.1 0.0 7.4 6 1 1 7 7 6 2 AAA ATPase domain AAA_22 PF13401.6 AIN99552.1 - 7.7e-11 42.4 0.3 0.11 12.8 0.0 6.3 5 0 0 5 5 5 2 AAA domain AAA PF00004.29 AIN99552.1 - 7.6e-10 39.3 0.1 0.17 12.3 0.0 6.3 6 0 0 6 6 5 2 ATPase family associated with various cellular activities (AAA) ABC_tran PF00005.27 AIN99552.1 - 8.2e-07 29.6 0.1 0.0012 19.4 0.0 4.5 3 0 0 3 3 3 1 ABC transporter RsgA_GTPase PF03193.16 AIN99552.1 - 1.5e-05 24.9 6.8 0.00065 19.6 0.0 4.2 4 0 0 4 4 3 1 RsgA GTPase RNA_helicase PF00910.22 AIN99552.1 - 1.5e-05 25.3 0.0 1.7 9.0 0.0 4.9 5 0 0 5 5 5 1 RNA helicase AAA_29 PF13555.6 AIN99552.1 - 2.8e-05 23.8 0.1 0.026 14.3 0.1 3.7 3 0 0 3 3 3 1 P-loop containing region of AAA domain AAA_30 PF13604.6 AIN99552.1 - 7.3e-05 22.6 0.2 0.04 13.6 0.0 3.2 2 0 0 2 2 2 1 AAA domain AAA_24 PF13479.6 AIN99552.1 - 7.7e-05 22.5 0.3 0.12 12.1 0.0 3.5 4 0 0 4 4 2 1 AAA domain AAA_18 PF13238.6 AIN99552.1 - 0.00033 21.2 0.1 0.15 12.6 0.0 4.1 4 0 0 4 4 2 1 AAA domain AAA_33 PF13671.6 AIN99552.1 - 0.0019 18.4 0.3 0.13 12.4 0.0 4.3 4 0 0 4 4 4 1 AAA domain AAA_28 PF13521.6 AIN99552.1 - 0.0028 17.9 3.6 0.051 13.8 0.0 4.0 4 0 0 4 4 3 1 AAA domain Rad17 PF03215.15 AIN99552.1 - 0.0062 16.5 0.3 1.3 8.9 0.0 3.6 3 0 0 3 3 3 1 Rad17 P-loop domain AAA_21 PF13304.6 AIN99552.1 - 0.0088 15.9 0.0 0.019 14.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system T2SSE PF00437.20 AIN99552.1 - 0.0097 15.0 0.0 0.04 13.0 0.0 2.1 1 0 0 1 1 1 1 Type II/IV secretion system protein Zeta_toxin PF06414.12 AIN99552.1 - 0.062 12.6 0.1 1.8 7.8 0.0 3.0 3 0 0 3 3 3 0 Zeta toxin PhoH PF02562.16 AIN99552.1 - 0.085 12.3 0.4 0.78 9.1 0.0 2.7 2 0 0 2 2 2 0 PhoH-like protein SMC_N PF02463.19 AIN99552.1 - 0.093 12.1 0.0 8.5 5.7 0.0 2.6 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_lid_7 PF17867.1 AIN99552.1 - 0.1 12.8 0.0 0.54 10.5 0.0 2.3 1 0 0 1 1 1 0 Midasin AAA lid domain ATP_bind_1 PF03029.17 AIN99552.1 - 0.16 11.7 1.6 6.5 6.4 0.0 3.7 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein ATPase_2 PF01637.18 AIN99552.1 - 0.21 11.5 5.8 1.4 8.7 0.0 3.5 4 0 0 4 4 2 0 ATPase domain predominantly from Archaea RPW8 PF05659.11 AIN99552.1 - 0.7 9.6 14.2 0.25 11.0 0.4 4.6 4 0 0 4 4 4 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 TMPIT PF07851.13 AIN99552.1 - 1.1 8.4 25.3 0.018 14.3 2.4 3.3 3 0 0 3 3 3 0 TMPIT-like protein ERM PF00769.19 AIN99552.1 - 2.7 7.8 47.0 0.015 15.1 13.2 3.9 3 1 0 3 3 2 0 Ezrin/radixin/moesin family Fib_alpha PF08702.10 AIN99552.1 - 2.9 8.1 28.1 0.49 10.6 0.5 5.5 5 0 0 5 5 4 0 Fibrinogen alpha/beta chain family DUF948 PF06103.11 AIN99552.1 - 3 8.1 9.5 47 4.3 3.5 5.1 3 1 0 3 3 3 0 Bacterial protein of unknown function (DUF948) TBCC PF07986.12 AIN99553.1 - 2.8e-25 88.4 5.6 7.1e-19 67.7 7.4 2.4 2 0 0 2 2 2 2 Tubulin binding cofactor C ComX PF05952.12 AIN99553.1 - 0.17 11.9 0.0 3.4 7.7 0.0 2.3 1 1 1 2 2 2 0 Bacillus competence pheromone ComX CAP_C PF08603.11 AIN99553.1 - 0.56 9.8 2.1 1.1 8.9 2.1 1.5 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) C terminal Pkinase PF00069.25 AIN99554.1 - 1.1e-22 80.6 0.0 1.1e-19 70.9 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 AIN99554.1 - 3.8e-10 39.5 0.0 5.9e-09 35.6 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 AIN99554.1 - 8.2e-08 31.4 0.1 1.1e-07 31.0 0.1 1.1 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 AIN99554.1 - 0.00018 20.9 0.2 0.0003 20.2 0.2 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 AIN99554.1 - 0.00048 20.1 0.1 0.0011 19.0 0.1 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 AIN99554.1 - 0.0011 18.6 0.1 0.003 17.2 0.1 1.6 2 0 0 2 2 2 1 RIO1 family Choline_kinase PF01633.20 AIN99554.1 - 0.056 13.0 0.0 0.1 12.1 0.0 1.5 1 1 0 1 1 1 0 Choline/ethanolamine kinase Lzipper-MIP1 PF14389.6 AIN99555.1 - 8.1 6.8 14.5 6.8 7.1 0.7 2.8 2 1 0 2 2 2 0 Leucine-zipper of ternary complex factor MIP1 Pkinase PF00069.25 AIN99556.1 - 3.8e-37 128.1 0.0 5.4e-37 127.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 AIN99556.1 - 6.6e-16 58.4 0.0 1e-15 57.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 AIN99556.1 - 0.28 9.9 2.2 0.44 9.3 0.0 2.1 2 0 0 2 2 2 0 Fungal protein kinase PEPCK_ATP PF01293.20 AIN99557.1 - 2.1e-194 646.6 0.0 2.6e-194 646.2 0.0 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase AAA_33 PF13671.6 AIN99557.1 - 0.14 12.3 0.0 0.26 11.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain FlxA PF14282.6 AIN99558.1 - 0.033 14.2 0.5 0.033 14.2 0.5 5.5 4 2 3 7 7 7 0 FlxA-like protein CENP-F_leu_zip PF10473.9 AIN99558.1 - 0.041 13.9 0.6 0.041 13.9 0.6 6.0 4 2 1 5 5 5 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Fumble PF03630.14 AIN99558.1 - 0.12 11.5 0.2 0.3 10.2 0.2 1.6 1 0 0 1 1 1 0 Fumble Spc7 PF08317.11 AIN99558.1 - 0.37 9.6 46.1 0.11 11.3 10.0 5.4 4 1 1 5 5 5 0 Spc7 kinetochore protein Cbl_N PF02262.16 AIN99558.1 - 0.58 10.2 0.0 0.58 10.2 0.0 3.2 3 0 0 3 3 3 0 CBL proto-oncogene N-terminal domain 1 DUF1759 PF03564.15 AIN99558.1 - 1 9.3 10.1 0.17 11.8 0.2 3.8 4 0 0 4 4 4 0 Protein of unknown function (DUF1759) Fmp27_WPPW PF10359.9 AIN99558.1 - 3.6 6.3 22.1 5.2 5.8 5.6 4.0 2 1 2 4 4 4 0 RNA pol II promoter Fmp27 protein domain PLAC9 PF15205.6 AIN99558.1 - 4.4 7.8 4.9 5.3 7.5 0.1 3.2 3 0 0 3 3 3 0 Placenta-specific protein 9 TMF_DNA_bd PF12329.8 AIN99559.1 - 0.011 15.7 1.7 0.011 15.7 1.7 8.4 8 2 0 8 8 8 0 TATA element modulatory factor 1 DNA binding Sas6_CC PF18594.1 AIN99559.1 - 2 8.3 5.3 2.8 7.8 0.1 3.3 3 0 0 3 3 3 0 Sas6/XLF/XRCC4 coiled-coil domain ATG_C PF09333.11 AIN99559.1 - 4.9 7.6 8.2 9 6.7 0.5 4.3 4 0 0 4 4 4 0 Autophagy-related protein C terminal domain YchF-GTPase_C PF06071.13 AIN99560.1 - 5.1e-24 84.3 0.1 1.2e-23 83.0 0.1 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF933) MMR_HSR1 PF01926.23 AIN99560.1 - 3.6e-21 75.4 0.0 7.7e-21 74.3 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 AIN99560.1 - 2.6e-07 30.3 0.0 6.3e-07 29.0 0.0 1.6 2 0 0 2 2 2 1 Ferrous iron transport protein B TGS PF02824.21 AIN99560.1 - 0.0018 18.3 0.0 0.0036 17.3 0.0 1.5 1 0 0 1 1 1 1 TGS domain ICA69 PF04629.14 AIN99560.1 - 0.046 14.0 0.2 0.072 13.4 0.2 1.2 1 0 0 1 1 1 0 Islet cell autoantigen ICA69, C-terminal domain MeaB PF03308.16 AIN99560.1 - 0.093 11.7 0.0 0.16 10.9 0.0 1.4 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB ABC_tran PF00005.27 AIN99560.1 - 0.17 12.4 0.0 0.37 11.3 0.0 1.8 1 1 0 1 1 1 0 ABC transporter DSPc PF00782.20 AIN99561.1 - 3.5e-25 88.4 0.0 5.5e-25 87.7 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 AIN99561.1 - 0.00052 19.6 0.0 0.001 18.7 0.0 1.4 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Gelsolin PF00626.22 AIN99561.1 - 0.048 13.6 0.0 0.23 11.4 0.0 2.1 2 0 0 2 2 2 0 Gelsolin repeat Flagellar_rod PF05149.12 AIN99562.1 - 1.3e-104 349.7 21.2 3e-104 348.5 21.2 1.6 1 0 0 1 1 1 1 Paraflagellar rod protein SH3_9 PF14604.6 AIN99562.1 - 1.1e-11 44.4 0.0 2.4e-11 43.3 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 AIN99562.1 - 1.5e-11 43.7 0.0 2.7e-11 42.9 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 AIN99562.1 - 7.7e-09 35.1 0.0 1.4e-08 34.2 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain Mlp PF03304.13 AIN99562.1 - 0.0054 17.0 7.8 0.3 11.3 3.6 2.8 2 1 0 2 2 2 2 Mlp lipoprotein family RRT14 PF17075.5 AIN99562.1 - 0.39 10.8 6.1 0.15 12.2 2.5 2.1 2 0 0 2 2 2 0 Regular of rDNA transcription protein 14 Cnl2_NKP2 PF09447.10 AIN99562.1 - 5.9 7.1 7.3 1.1 9.4 0.8 3.3 4 0 0 4 4 4 0 Cnl2/NKP2 family protein GSP_synth PF03738.14 AIN99564.1 - 3.7e-71 240.3 0.0 4.7e-71 239.9 0.0 1.1 1 0 0 1 1 1 1 Glutathionylspermidine synthase preATP-grasp CHAP PF05257.16 AIN99564.1 - 2.5e-09 37.6 0.0 5.7e-09 36.4 0.0 1.6 1 0 0 1 1 1 1 CHAP domain YCII PF03795.14 AIN99565.1 - 0.1 13.0 0.1 0.24 11.8 0.1 1.6 1 0 0 1 1 1 0 YCII-related domain Mre11_DNA_bind PF04152.14 AIN99566.1 - 2.2e-26 93.2 0.0 6.8e-26 91.6 0.0 1.8 2 0 0 2 2 2 1 Mre11 DNA-binding presumed domain Metallophos PF00149.28 AIN99566.1 - 1.3e-13 51.9 0.2 2.6e-13 50.9 0.2 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 AIN99566.1 - 0.0063 16.7 0.0 0.16 12.1 0.0 2.9 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain PSD5 PF07637.11 AIN99567.1 - 0.023 15.0 0.7 0.12 12.8 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1595) DICT PF10069.9 AIN99567.1 - 0.026 14.3 0.2 0.66 9.8 0.1 2.6 2 0 0 2 2 2 0 Sensory domain in DIguanylate Cyclases and Two-component system bZIP_2 PF07716.15 AIN99567.1 - 0.094 12.8 0.6 0.26 11.4 0.6 1.7 1 0 0 1 1 1 0 Basic region leucine zipper DUF846 PF05832.12 AIN99568.1 - 4e-44 150.0 13.4 5.6e-44 149.6 13.4 1.2 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF846) TM1586_NiRdase PF14512.6 AIN99569.1 - 0.048 13.2 0.1 0.078 12.5 0.1 1.5 1 1 0 1 1 1 0 Putative TM nitroreductase DUF3611 PF12263.8 AIN99571.1 - 0.016 15.1 0.2 0.016 15.1 0.2 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3611) Amastin PF07344.11 AIN99571.1 - 0.03 14.2 0.1 0.069 13.0 0.0 1.6 1 1 0 1 1 1 0 Amastin surface glycoprotein 7TM_GPCR_Srv PF10323.9 AIN99571.1 - 0.14 11.5 5.0 0.15 11.4 3.2 1.8 2 0 0 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srv BCAS3 PF12490.8 AIN99572.1 - 0.0036 16.9 0.2 0.0041 16.7 0.2 1.2 1 0 0 1 1 1 1 Breast carcinoma amplified sequence 3 Pkinase PF00069.25 AIN99573.1 - 1.9e-44 152.0 0.0 6.6e-41 140.4 0.0 3.0 3 1 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 AIN99573.1 - 1.3e-22 80.3 0.0 2.9e-21 75.9 0.0 2.4 2 1 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 AIN99573.1 - 9.2e-08 31.7 0.0 1.6e-07 30.9 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 AIN99573.1 - 0.0002 20.5 0.0 0.0003 19.8 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Pkinase_fungal PF17667.1 AIN99573.1 - 0.12 11.1 0.0 0.21 10.3 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase Dpy-30 PF05186.13 AIN99574.1 - 0.0051 16.5 0.0 0.01 15.5 0.0 1.5 1 0 0 1 1 1 1 Dpy-30 motif Hydin_ADK PF17213.3 AIN99574.1 - 0.038 14.3 0.3 0.038 14.3 0.3 2.9 3 0 0 3 3 3 0 Hydin Adenylate kinase-like domain Selenoprotein_S PF06936.11 AIN99574.1 - 2.1 8.1 8.1 0.43 10.4 4.4 1.7 2 0 0 2 2 2 0 Selenoprotein S (SelS) BUD22 PF09073.10 AIN99574.1 - 3.3 6.9 32.7 0.049 13.0 8.9 3.6 3 0 0 3 3 3 0 BUD22 IFT43 PF15305.6 AIN99575.1 - 6.7e-06 26.3 0.4 1.8e-05 25.0 0.4 1.7 1 0 0 1 1 1 1 Intraflagellar transport protein 43 LSM PF01423.22 AIN99576.1 - 1.4e-17 63.2 0.4 1.7e-17 62.9 0.4 1.1 1 0 0 1 1 1 1 LSM domain FtsJ PF01728.19 AIN99577.1 - 8.2e-55 185.6 0.0 1.3e-54 185.0 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase Spb1_C PF07780.12 AIN99577.1 - 2.7e-30 105.6 17.4 2.7e-30 105.6 17.4 3.3 3 0 0 3 3 3 1 Spb1 C-terminal domain DUF3381 PF11861.8 AIN99577.1 - 4e-29 101.5 1.8 4e-29 101.5 1.8 4.5 4 1 0 4 4 4 1 Domain of unknown function (DUF3381) TrmB PF01978.19 AIN99577.1 - 0.079 12.9 0.2 0.26 11.2 0.2 1.9 1 1 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB RabGAP-TBC PF00566.18 AIN99578.1 - 5.7e-28 98.0 0.2 1.7e-15 57.3 0.0 3.4 4 0 0 4 4 4 3 Rab-GTPase-TBC domain GMP_PDE_delta PF05351.11 AIN99579.1 - 3.5e-62 209.1 0.0 4e-62 208.9 0.0 1.0 1 0 0 1 1 1 1 GMP-PDE, delta subunit ATG16 PF08614.11 AIN99580.1 - 0.0011 19.2 2.3 0.002 18.4 2.3 1.5 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) ubiquitin PF00240.23 AIN99580.1 - 0.046 13.5 0.2 0.32 10.8 0.0 2.1 2 0 0 2 2 2 0 Ubiquitin family ST7 PF04184.12 AIN99580.1 - 0.14 10.6 1.1 0.19 10.1 1.1 1.1 1 0 0 1 1 1 0 ST7 protein FAD-oxidase_C PF02913.19 AIN99581.1 - 2.4e-40 138.7 0.1 4.2e-40 137.9 0.1 1.4 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 AIN99581.1 - 3.7e-36 123.9 2.7 6.6e-36 123.1 2.1 1.8 2 0 0 2 2 2 1 FAD binding domain Aminotran_4 PF01063.19 AIN99582.1 - 7.9e-31 107.6 0.0 1e-30 107.3 0.0 1.2 1 0 0 1 1 1 1 Amino-transferase class IV Erv26 PF04148.13 AIN99583.1 - 5.2e-18 65.6 14.5 3e-17 63.2 14.5 1.8 1 1 0 1 1 1 1 Transmembrane adaptor Erv26 Ion_trans PF00520.31 AIN99583.1 - 0.47 9.6 13.7 1.5 8.0 8.5 2.1 2 0 0 2 2 2 0 Ion transport protein DUF5090 PF17009.5 AIN99583.1 - 5.5 6.9 10.8 18 5.3 10.8 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF5090) Ribonuc_red_sm PF00268.21 AIN99584.1 - 4.3e-111 370.9 0.1 5.3e-111 370.6 0.1 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain NMT PF01233.19 AIN99584.1 - 0.11 12.4 0.0 0.19 11.5 0.0 1.3 1 0 0 1 1 1 0 Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain OCRE PF17780.1 AIN99586.1 - 6.3e-05 22.9 2.1 0.00013 21.9 2.1 1.4 1 0 0 1 1 1 1 OCRE domain DUF4064 PF13273.6 AIN99586.1 - 0.35 11.2 2.3 2.3 8.5 2.4 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF4064) Noelin-1 PF12308.8 AIN99587.1 - 0.1 12.6 0.1 0.13 12.3 0.1 1.3 1 1 0 1 1 1 0 Neurogenesis glycoprotein RRM_1 PF00076.22 AIN99589.1 - 8.2e-32 108.8 0.0 2e-12 46.7 0.0 3.4 3 1 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 AIN99589.1 - 3.7e-10 39.6 0.1 4.9e-06 26.5 0.0 3.3 3 0 0 3 3 3 2 Nup53/35/40-type RNA recognition motif RRM_occluded PF16842.5 AIN99589.1 - 3.5e-07 30.0 0.0 0.00015 21.5 0.0 2.4 2 0 0 2 2 2 2 Occluded RNA-recognition motif RRM_7 PF16367.5 AIN99589.1 - 2.3e-05 24.4 0.1 0.028 14.5 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif zf-CCHC PF00098.23 AIN99589.1 - 0.00072 19.5 0.5 0.0016 18.5 0.5 1.6 1 0 0 1 1 1 1 Zinc knuckle Nucleoporin_FG2 PF15967.5 AIN99589.1 - 0.028 13.0 0.3 0.028 13.0 0.3 1.6 1 1 0 1 1 1 0 Nucleoporin FG repeated region RRM_3 PF08777.11 AIN99589.1 - 0.032 14.3 0.0 2.7 8.1 0.0 3.0 3 0 0 3 3 3 0 RNA binding motif zf-CCHC_3 PF13917.6 AIN99589.1 - 0.042 13.8 2.3 0.093 12.7 2.3 1.5 1 0 0 1 1 1 0 Zinc knuckle Lipase_3 PF01764.25 AIN99590.1 - 2.1e-14 53.6 0.0 1.2e-11 44.6 0.0 2.5 2 0 0 2 2 2 2 Lipase (class 3) Hydrolase_4 PF12146.8 AIN99590.1 - 0.0066 15.7 0.0 0.014 14.7 0.0 1.5 1 0 0 1 1 1 1 Serine aminopeptidase, S33 DUF2974 PF11187.8 AIN99590.1 - 0.11 12.1 0.0 0.91 9.0 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2974) Motile_Sperm PF00635.26 AIN99591.1 - 2.2e-06 27.5 0.0 5.7e-06 26.1 0.0 1.8 1 1 0 1 1 1 1 MSP (Major sperm protein) domain PI3_PI4_kinase PF00454.27 AIN99593.1 - 5.7e-20 72.2 0.0 1e-19 71.4 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase DUF1465 PF07323.12 AIN99593.1 - 0.07 13.0 1.0 0.18 11.7 0.3 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1465) WD40 PF00400.32 AIN99596.1 - 2.9e-13 50.1 1.3 0.0027 18.5 0.2 7.0 7 0 0 7 7 7 3 WD domain, G-beta repeat BORCS6 PF10157.9 AIN99596.1 - 0.022 15.0 0.1 0.022 15.0 0.1 2.9 3 1 1 4 4 4 0 BLOC-1-related complex sub-unit 6 DUF603 PF04645.12 AIN99596.1 - 0.13 12.0 2.1 0.28 10.9 0.6 2.3 2 0 0 2 2 2 0 Protein of unknown function, DUF603 NIF PF03031.18 AIN99597.1 - 3.4e-26 91.9 0.0 5.2e-26 91.3 0.0 1.3 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase VKOR PF07884.14 AIN99598.1 - 8.1e-18 64.8 16.9 9.7e-18 64.5 16.9 1.1 1 0 0 1 1 1 1 Vitamin K epoxide reductase family Thioredoxin PF00085.20 AIN99599.1 - 2.9e-06 27.2 0.0 5.4e-06 26.3 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin Phosducin PF02114.16 AIN99599.1 - 0.00011 21.2 0.1 0.00012 21.1 0.1 1.1 1 0 0 1 1 1 1 Phosducin DSPc PF00782.20 AIN99600.1 - 7.3e-29 100.3 0.0 1e-28 99.8 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 AIN99600.1 - 0.0027 17.3 0.0 0.0038 16.8 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Ribosomal_L11_N PF03946.14 AIN99601.1 - 1.8e-15 56.5 0.0 3e-15 55.8 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.19 AIN99601.1 - 8.4e-15 55.0 0.0 1.5e-14 54.3 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain DUF1451 PF07295.11 AIN99602.1 - 0.014 15.4 0.7 0.092 12.8 0.7 2.5 1 0 0 1 1 1 0 Zinc-ribbon containing domain Atg14 PF10186.9 AIN99603.1 - 7.1e-07 28.6 3.9 1.2e-06 27.8 3.9 1.3 1 0 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 Bap31_Bap29_C PF18035.1 AIN99603.1 - 0.016 15.2 4.8 0.038 14.0 4.8 1.6 1 0 0 1 1 1 0 Bap31/Bap29 cytoplasmic coiled-coil domain TFIIA PF03153.13 AIN99603.1 - 1.3 8.9 11.5 2.5 8.0 11.5 1.3 1 1 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit T4bSS_IcmS PF12608.8 AIN99603.1 - 1.5 9.2 3.6 0.87 9.9 0.8 2.1 2 1 0 2 2 2 0 Type IVb secretion, IcmS, effector-recruitment EMG1 PF03587.14 AIN99604.1 - 8.5e-39 133.2 0.0 1.1e-38 132.9 0.0 1.1 1 0 0 1 1 1 1 EMG1/NEP1 methyltransferase Herpes_UL25 PF01499.16 AIN99606.1 - 0.92 7.9 5.0 1.7 7.1 5.0 1.4 1 0 0 1 1 1 0 Herpesvirus UL25 family Mcp5_PH PF12814.7 AIN99607.1 - 3.6e-15 56.2 0.4 4.3e-15 55.9 0.4 1.1 1 0 0 1 1 1 1 Meiotic cell cortex C-terminal pleckstrin homology PH PF00169.29 AIN99607.1 - 0.00012 22.6 0.5 0.00014 22.3 0.5 1.1 1 0 0 1 1 1 1 PH domain PH_2 PF08458.10 AIN99607.1 - 0.012 16.0 1.0 0.013 15.9 0.0 1.5 2 0 0 2 2 2 0 Plant pleckstrin homology-like region ACOX PF01756.19 AIN99608.1 - 7.2e-09 35.4 0.1 1.7e-08 34.3 0.0 1.6 2 0 0 2 2 2 1 Acyl-CoA oxidase DUF384 PF04064.13 AIN99608.1 - 0.12 12.2 0.0 0.27 11.1 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF384) Spt5-NGN PF03439.13 AIN99609.1 - 1.4e-21 76.1 0.3 7.4e-21 73.8 0.1 2.3 2 0 0 2 2 2 1 Early transcription elongation factor of RNA pol II, NGN section KOW PF00467.29 AIN99609.1 - 1.8e-06 27.6 5.4 0.075 13.0 0.1 4.2 4 0 0 4 4 4 2 KOW motif HAS-barrel PF09378.10 AIN99609.1 - 0.0013 18.9 0.6 0.37 11.0 0.0 3.3 3 0 0 3 3 3 1 HAS barrel domain Hormone_3 PF00159.18 AIN99609.1 - 0.072 13.2 2.0 4.4 7.5 0.3 2.6 2 0 0 2 2 2 0 Pancreatic hormone peptide MORN PF02493.20 AIN99610.1 - 8.1e-20 69.5 15.8 2.8e-06 26.9 0.1 4.6 5 0 0 5 5 5 4 MORN repeat PP2C PF00481.21 AIN99612.1 - 3.6e-75 252.9 0.0 4.5e-75 252.6 0.0 1.0 1 0 0 1 1 1 1 Protein phosphatase 2C SCRL PF06876.12 AIN99612.1 - 0.062 13.5 0.1 0.18 12.0 0.1 1.7 1 0 0 1 1 1 0 Plant self-incompatibility response (SCRL) protein YchF-GTPase_C PF06071.13 AIN99613.1 - 3.5e-37 126.5 0.4 8.3e-37 125.2 0.4 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF933) MMR_HSR1 PF01926.23 AIN99613.1 - 5.5e-22 78.0 0.0 4.4e-21 75.1 0.0 2.2 1 1 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 AIN99613.1 - 0.0002 20.9 0.0 0.00055 19.5 0.0 1.7 2 0 0 2 2 2 1 Ferrous iron transport protein B TGS PF02824.21 AIN99613.1 - 0.026 14.6 0.0 0.058 13.4 0.0 1.6 1 0 0 1 1 1 0 TGS domain MeaB PF03308.16 AIN99613.1 - 0.031 13.3 0.0 0.05 12.6 0.0 1.3 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Roc PF08477.13 AIN99613.1 - 0.04 14.1 0.0 0.91 9.8 0.0 2.4 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_18 PF13238.6 AIN99613.1 - 0.046 14.3 0.0 0.15 12.6 0.0 1.9 2 0 0 2 2 2 0 AAA domain Dynamin_N PF00350.23 AIN99613.1 - 0.077 13.1 0.2 14 5.7 0.1 2.6 2 1 1 3 3 3 0 Dynamin family Cpn60_TCP1 PF00118.24 AIN99615.1 - 0.043 12.5 0.0 0.062 11.9 0.0 1.1 1 0 0 1 1 1 0 TCP-1/cpn60 chaperonin family Glyco_hydro_32N PF00251.20 AIN99616.1 - 5.5e-86 288.9 1.0 6.8e-86 288.6 1.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 N-terminal domain Glyco_hydro_32C PF08244.12 AIN99616.1 - 1.2e-19 70.8 0.0 1.8e-19 70.2 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 C terminal zf_CopZ PF18423.1 AIN99616.1 - 0.063 13.2 0.3 0.15 12.0 0.3 1.6 1 0 0 1 1 1 0 Zinc binding domain RPAP3_C PF13877.6 AIN99618.1 - 6e-15 55.6 0.0 1.1e-14 54.7 0.0 1.5 1 0 0 1 1 1 1 Potential Monad-binding region of RPAP3 TPR_2 PF07719.17 AIN99618.1 - 2.3e-13 49.1 2.7 9.3e-05 22.3 0.8 4.2 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.28 AIN99618.1 - 9e-12 44.3 2.3 6.3e-05 22.6 0.3 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 AIN99618.1 - 6.5e-10 38.4 1.7 0.0004 20.4 0.1 4.1 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_11 PF13414.6 AIN99618.1 - 2.8e-07 30.1 2.7 0.00058 19.5 0.0 3.7 3 2 2 5 5 5 2 TPR repeat TPR_9 PF13371.6 AIN99618.1 - 2.6e-05 24.3 1.2 2.6e-05 24.3 1.2 4.8 3 1 2 5 5 4 3 Tetratricopeptide repeat TPR_17 PF13431.6 AIN99618.1 - 0.00014 22.0 0.3 0.81 10.2 0.0 3.1 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.6 AIN99618.1 - 0.00021 21.8 2.8 0.0025 18.5 1.7 5.0 6 1 1 7 7 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 AIN99618.1 - 0.00029 21.3 4.0 0.093 13.3 0.0 3.6 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 AIN99618.1 - 0.00034 21.2 1.4 0.00034 21.2 1.4 5.1 4 1 3 7 7 7 2 Tetratricopeptide repeat TPR_12 PF13424.6 AIN99618.1 - 0.0025 18.1 5.3 0.041 14.2 3.9 3.1 2 1 0 2 2 1 1 Tetratricopeptide repeat ANAPC3 PF12895.7 AIN99618.1 - 0.0032 17.7 1.2 0.0091 16.2 1.2 1.8 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 MRP-L28 PF09812.9 AIN99618.1 - 0.01 16.0 0.1 0.01 16.0 0.1 2.6 2 0 0 2 2 2 0 Mitochondrial ribosomal protein L28 TPR_7 PF13176.6 AIN99618.1 - 0.08 13.0 5.5 23 5.3 0.3 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.6 AIN99618.1 - 0.11 13.2 12.4 0.19 12.4 0.8 4.0 4 0 0 4 4 2 0 Tetratricopeptide repeat Rrn6 PF10214.9 AIN99618.1 - 1.9 6.9 14.2 2.8 6.3 14.2 1.3 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor DUF966 PF06136.13 AIN99618.1 - 9.7 5.8 16.4 16 5.1 16.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF966) Synaptobrevin PF00957.21 AIN99619.1 - 9.3e-25 86.3 0.7 1.5e-24 85.6 0.7 1.3 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.6 AIN99619.1 - 3.4e-10 39.8 0.2 5.9e-10 39.0 0.2 1.4 1 0 0 1 1 1 1 Regulated-SNARE-like domain HHV-5_US34A PF17087.5 AIN99621.1 - 0.14 12.3 2.3 0.36 11.0 1.5 2.1 2 1 0 2 2 2 0 Herpesvirus US34A protein family DnaJ_C PF01556.18 AIN99622.1 - 3.9e-32 111.4 0.0 5.1e-32 111.0 0.0 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 AIN99622.1 - 3.9e-28 97.4 1.2 1.3e-27 95.7 0.3 2.0 2 0 0 2 2 2 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 AIN99622.1 - 2.4e-14 53.4 16.0 4e-14 52.7 16.0 1.4 1 0 0 1 1 1 1 DnaJ central domain Anti-TRAP PF15777.5 AIN99622.1 - 0.12 12.3 14.6 0.34 10.9 3.3 2.6 1 1 1 2 2 2 0 Tryptophan RNA-binding attenuator protein inhibitory protein HypA PF01155.19 AIN99622.1 - 1 9.4 10.8 1.2 9.2 1.0 2.6 1 1 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DZR PF12773.7 AIN99622.1 - 2.9 8.0 12.5 1.9e+02 2.2 12.5 2.6 1 1 0 1 1 1 0 Double zinc ribbon RseC_MucC PF04246.12 AIN99622.1 - 6.6 6.7 9.1 0.49 10.4 1.2 2.2 2 0 0 2 2 2 0 Positive regulator of sigma(E), RseC/MucC Aldo_ket_red PF00248.21 AIN99623.1 - 6.7e-34 117.4 0.0 1.3e-33 116.4 0.0 1.4 1 1 0 1 1 1 1 Aldo/keto reductase family TBPIP PF07106.13 AIN99624.1 - 4.2e-08 33.0 0.0 6e-08 32.5 0.0 1.2 1 0 0 1 1 1 1 TBPIP/Hop2 winged helix domain Cep57_MT_bd PF06657.13 AIN99624.1 - 0.042 14.3 0.2 0.13 12.8 0.0 1.8 2 0 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 adh_short_C2 PF13561.6 AIN99626.1 - 1.2e-41 142.9 0.2 1.2e-41 142.8 0.2 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 AIN99626.1 - 5.7e-36 123.8 0.1 8.2e-36 123.3 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 AIN99626.1 - 1.7e-12 47.6 1.1 7.2e-12 45.6 1.1 1.8 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 AIN99626.1 - 4e-05 23.2 0.0 0.00012 21.6 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 AIN99626.1 - 0.12 11.5 0.1 0.18 10.9 0.1 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain ExoD PF06055.12 AIN99627.1 - 0.035 13.5 0.0 0.084 12.3 0.0 1.6 1 0 0 1 1 1 0 Exopolysaccharide synthesis, ExoD Pkinase PF00069.25 AIN99628.1 - 9.5e-51 172.7 0.0 2.1e-50 171.6 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 AIN99628.1 - 3e-24 85.7 0.0 5.3e-24 84.9 0.0 1.3 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 AIN99628.1 - 8.2e-05 22.0 0.0 0.032 13.5 0.0 2.3 2 0 0 2 2 2 2 Kinase-like Kdo PF06293.14 AIN99628.1 - 0.004 16.5 0.0 0.0054 16.1 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 AIN99628.1 - 0.0058 16.6 0.5 0.2 11.5 0.1 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family DHDPS PF00701.22 AIN99628.1 - 0.007 15.1 0.0 0.0098 14.6 0.0 1.1 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family Pkinase_fungal PF17667.1 AIN99628.1 - 0.054 12.3 0.0 0.061 12.1 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase Pkinase PF00069.25 AIN99629.1 - 2.3e-65 220.6 0.0 3.6e-65 220.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 AIN99629.1 - 8.2e-30 103.9 0.0 1.2e-29 103.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 AIN99629.1 - 0.0002 20.8 0.0 0.0043 16.4 0.0 2.3 1 1 0 2 2 2 1 Kinase-like Kdo PF06293.14 AIN99629.1 - 0.017 14.5 0.5 0.22 10.8 0.0 2.3 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Prp19 PF08606.11 AIN99630.1 - 2.2e-24 85.2 0.2 4.7e-24 84.2 0.2 1.5 1 0 0 1 1 1 1 Prp19/Pso4-like WD40 PF00400.32 AIN99630.1 - 1.8e-07 31.7 12.0 0.33 11.9 0.0 6.0 6 0 0 6 6 6 3 WD domain, G-beta repeat PALB2_WD40 PF16756.5 AIN99630.1 - 0.012 14.6 0.1 0.19 10.6 0.0 2.2 1 1 0 2 2 2 0 Partner and localizer of BRCA2 WD40 domain Frtz PF11768.8 AIN99630.1 - 0.02 13.2 0.0 3.5 5.8 0.0 2.2 1 1 1 2 2 2 0 WD repeat-containing and planar cell polarity effector protein Fritz U-box PF04564.15 AIN99630.1 - 0.022 14.9 0.0 0.048 13.8 0.0 1.5 1 0 0 1 1 1 0 U-box domain zf-Nse PF11789.8 AIN99630.1 - 0.03 14.2 0.1 0.059 13.2 0.1 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit ANAPC4_WD40 PF12894.7 AIN99630.1 - 0.11 12.8 0.1 20 5.6 0.0 3.9 1 1 2 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain TTL PF03133.15 AIN99631.1 - 5.4e-48 163.6 0.0 7.9e-48 163.1 0.0 1.1 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 AIN99631.1 - 0.00011 21.5 0.0 0.16 11.2 0.0 2.9 2 1 0 2 2 2 2 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 AIN99631.1 - 0.022 14.0 0.0 0.053 12.8 0.0 1.5 2 0 0 2 2 2 0 Sugar-transfer associated ATP-grasp Dala_Dala_lig_C PF07478.13 AIN99631.1 - 0.052 13.1 0.0 0.085 12.4 0.0 1.2 1 0 0 1 1 1 0 D-ala D-ala ligase C-terminus Kri1 PF05178.12 AIN99632.1 - 5.4 7.6 9.3 0.34 11.5 4.5 1.4 2 0 0 2 2 2 0 KRI1-like family AAA_6 PF12774.7 AIN99633.1 - 1.4e-155 517.2 0.0 4.3e-153 509.0 0.0 3.2 3 0 0 3 3 3 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 AIN99633.1 - 1.2e-115 386.9 7.3 3.5e-115 385.3 7.3 1.9 1 0 0 1 1 1 1 Dynein heavy chain, N-terminal region 2 Dynein_C PF18199.1 AIN99633.1 - 1.1e-108 363.2 0.0 3.4e-108 361.5 0.0 1.9 2 0 0 2 2 2 1 Dynein heavy chain C-terminal domain AAA_8 PF12780.7 AIN99633.1 - 9e-91 303.8 0.0 2.4e-90 302.4 0.0 1.8 1 0 0 1 1 1 1 P-loop containing dynein motor region D4 AAA_7 PF12775.7 AIN99633.1 - 1e-75 253.2 0.0 1e-72 243.5 0.0 2.6 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA_9 PF12781.7 AIN99633.1 - 5.3e-73 244.8 4.1 1.2e-72 243.6 4.1 1.7 1 0 0 1 1 1 1 ATP-binding dynein motor region AAA_lid_11 PF18198.1 AIN99633.1 - 2.5e-59 199.7 0.0 6.6e-59 198.4 0.0 1.8 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain Dynein_heavy PF03028.15 AIN99633.1 - 3.5e-38 130.4 0.0 4e-36 123.7 0.0 2.9 2 0 0 2 2 2 1 Dynein heavy chain region D6 P-loop domain MT PF12777.7 AIN99633.1 - 2.5e-27 95.8 8.7 2.5e-27 95.8 8.7 2.1 2 0 0 2 2 2 1 Microtubule-binding stalk of dynein motor Dynein_AAA_lid PF17852.1 AIN99633.1 - 2.6e-20 72.8 0.0 7.3e-20 71.4 0.0 1.9 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain AAA_5 PF07728.14 AIN99633.1 - 1.7e-18 66.9 0.0 4.8e-05 23.4 0.0 6.0 5 2 1 6 6 6 3 AAA domain (dynein-related subfamily) AAA_lid_1 PF17857.1 AIN99633.1 - 5e-14 52.3 0.0 1.7e-13 50.6 0.0 2.0 1 0 0 1 1 1 1 AAA+ lid domain AAA PF00004.29 AIN99633.1 - 5.4e-09 36.6 2.5 0.0029 18.0 0.0 4.1 4 0 0 4 4 3 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 AIN99633.1 - 1.2e-06 28.9 6.7 0.023 14.9 0.0 6.3 8 0 0 8 8 5 2 AAA domain AAA_30 PF13604.6 AIN99633.1 - 2e-05 24.4 2.9 0.072 12.8 0.0 3.7 3 0 0 3 3 3 2 AAA domain AAA_18 PF13238.6 AIN99633.1 - 9.5e-05 22.9 0.0 0.0074 16.8 0.0 3.6 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 AIN99633.1 - 0.00017 22.0 13.3 0.13 12.6 0.0 7.4 7 0 0 7 7 6 1 AAA ATPase domain RNA_helicase PF00910.22 AIN99633.1 - 0.0034 17.8 0.1 3.2 8.2 0.0 3.2 2 0 0 2 2 2 1 RNA helicase T2SSE PF00437.20 AIN99633.1 - 0.0061 15.7 0.8 0.061 12.4 0.0 3.0 3 0 0 3 3 3 1 Type II/IV secretion system protein AAA_33 PF13671.6 AIN99633.1 - 0.012 15.8 0.1 3.7 7.7 0.0 3.9 3 0 0 3 3 3 0 AAA domain DUF815 PF05673.13 AIN99633.1 - 0.013 14.7 0.0 0.042 13.0 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF815) DUF853 PF05872.12 AIN99633.1 - 0.018 13.7 0.9 1 7.8 0.0 3.1 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF853) TsaE PF02367.17 AIN99633.1 - 0.02 14.9 1.6 1.5 8.8 0.0 3.5 3 0 0 3 3 3 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE MobB PF03205.14 AIN99633.1 - 0.039 13.8 0.0 0.11 12.4 0.0 1.8 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B IstB_IS21 PF01695.17 AIN99633.1 - 0.073 12.8 0.0 0.75 9.5 0.0 2.5 2 0 0 2 2 2 0 IstB-like ATP binding protein RBD-FIP PF09457.10 AIN99633.1 - 0.082 12.8 2.9 0.38 10.7 0.0 3.3 3 0 0 3 3 2 0 FIP domain CbiA PF01656.23 AIN99633.1 - 0.088 12.9 0.0 2 8.5 0.0 2.7 2 0 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain ResIII PF04851.15 AIN99633.1 - 0.26 11.3 1.1 0.91 9.5 0.0 2.5 2 0 0 2 2 1 0 Type III restriction enzyme, res subunit TPR_12 PF13424.6 AIN99633.1 - 0.28 11.5 5.3 2.4 8.5 0.3 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF1664 PF07889.12 AIN99633.1 - 7.3 6.6 9.6 2.8 8.0 0.3 4.0 3 1 1 4 4 4 0 Protein of unknown function (DUF1664) AAA_25 PF13481.6 AIN99635.1 - 0.049 13.2 1.3 0.082 12.5 0.0 1.9 2 0 0 2 2 2 0 AAA domain FmiP_Thoc5 PF09766.9 AIN99635.1 - 0.25 10.6 4.9 0.49 9.6 4.9 1.5 1 0 0 1 1 1 0 Fms-interacting protein/Thoc5 KxDL PF10241.9 AIN99635.1 - 0.29 11.4 6.1 0.7 10.2 4.1 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein CREPT PF16566.5 AIN99635.1 - 3.8 7.7 11.6 2.1 8.5 1.8 2.7 2 1 1 3 3 3 0 Cell-cycle alteration and expression-elevated protein in tumour DUF2316 PF10078.9 AIN99636.1 - 0.074 13.3 4.2 3.5 7.9 0.4 3.9 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2316) AAA_2 PF07724.14 AIN99637.1 - 1.2e-52 178.5 0.0 4.6e-50 170.1 0.0 2.6 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_lid_9 PF17871.1 AIN99637.1 - 6.7e-32 109.5 2.5 6.7e-32 109.5 2.5 2.3 2 0 0 2 2 2 1 AAA lid domain AAA PF00004.29 AIN99637.1 - 2e-23 83.3 0.1 9.2e-14 52.0 0.0 3.1 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.9 AIN99637.1 - 1.1e-21 76.7 0.2 3.5e-21 75.1 0.2 2.0 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA_5 PF07728.14 AIN99637.1 - 3.7e-18 65.9 0.3 3.3e-10 40.1 0.0 4.2 4 0 0 4 4 4 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 AIN99637.1 - 4.6e-11 43.4 4.0 7.1e-05 23.2 0.3 4.4 3 2 0 3 3 3 2 AAA ATPase domain AAA_22 PF13401.6 AIN99637.1 - 2.2e-08 34.5 5.4 0.0037 17.5 0.0 5.2 4 3 1 5 5 4 2 AAA domain AAA_7 PF12775.7 AIN99637.1 - 9.9e-07 28.4 0.0 0.0059 16.1 0.0 2.8 2 1 0 2 2 2 2 P-loop containing dynein motor region Mg_chelatase PF01078.21 AIN99637.1 - 4.2e-05 23.0 0.0 0.35 10.2 0.0 3.3 3 0 0 3 3 3 2 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 AIN99637.1 - 5e-05 23.1 0.1 0.071 12.8 0.0 2.9 3 0 0 3 3 3 1 IstB-like ATP binding protein AAA_18 PF13238.6 AIN99637.1 - 5.2e-05 23.8 1.0 0.084 13.4 0.0 3.3 3 1 0 3 3 3 1 AAA domain RNA_helicase PF00910.22 AIN99637.1 - 5.9e-05 23.4 0.0 0.84 10.0 0.0 3.0 3 0 0 3 3 2 2 RNA helicase AAA_14 PF13173.6 AIN99637.1 - 0.0004 20.4 0.0 0.42 10.6 0.0 3.1 2 0 0 2 2 2 1 AAA domain Sigma54_activat PF00158.26 AIN99637.1 - 0.00042 20.0 0.0 0.28 10.9 0.0 2.8 2 1 0 2 2 2 1 Sigma-54 interaction domain RuvB_N PF05496.12 AIN99637.1 - 0.00054 19.8 0.1 2 8.2 0.0 3.4 3 0 0 3 3 3 1 Holliday junction DNA helicase RuvB P-loop domain NACHT PF05729.12 AIN99637.1 - 0.00062 19.7 0.0 0.052 13.5 0.0 3.3 3 0 0 3 3 3 1 NACHT domain ATPase_2 PF01637.18 AIN99637.1 - 0.00076 19.5 2.5 1.8 8.4 0.1 4.3 2 2 0 3 3 3 1 ATPase domain predominantly from Archaea AAA_3 PF07726.11 AIN99637.1 - 0.0013 18.6 0.0 1.1 9.1 0.0 3.2 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Roc PF08477.13 AIN99637.1 - 0.0017 18.6 0.0 1.4 9.2 0.0 2.8 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase AAA_19 PF13245.6 AIN99637.1 - 0.0024 18.2 0.0 0.34 11.2 0.1 3.3 3 1 0 3 3 3 1 AAA domain DNA_pol3_delta2 PF13177.6 AIN99637.1 - 0.0035 17.2 1.8 4.3 7.1 0.0 3.5 3 1 0 3 3 3 1 DNA polymerase III, delta subunit ResIII PF04851.15 AIN99637.1 - 0.0037 17.3 0.0 2.3 8.2 0.0 3.5 2 1 0 3 3 3 1 Type III restriction enzyme, res subunit DUF815 PF05673.13 AIN99637.1 - 0.0053 16.0 0.2 0.15 11.2 0.0 3.1 3 1 0 3 3 3 1 Protein of unknown function (DUF815) TsaE PF02367.17 AIN99637.1 - 0.007 16.4 0.0 2.9 7.9 0.0 2.6 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE SRP54 PF00448.22 AIN99637.1 - 0.0091 15.6 0.0 1.4 8.5 0.0 3.1 3 0 0 3 3 3 1 SRP54-type protein, GTPase domain RsgA_GTPase PF03193.16 AIN99637.1 - 0.01 15.8 0.0 3.4 7.5 0.0 2.9 2 0 0 2 2 2 0 RsgA GTPase AAA_24 PF13479.6 AIN99637.1 - 0.012 15.4 0.0 7.6 6.2 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 AIN99637.1 - 0.013 15.7 0.0 8.5 6.5 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 AIN99637.1 - 0.013 15.7 0.2 2.9 8.1 0.0 3.2 4 0 0 4 4 2 0 AAA domain Torsin PF06309.11 AIN99637.1 - 0.015 15.4 0.0 0.052 13.7 0.0 1.9 2 0 0 2 2 1 0 Torsin Ribosomal_S7 PF00177.21 AIN99637.1 - 0.024 14.3 0.0 0.076 12.7 0.0 1.8 1 0 0 1 1 1 0 Ribosomal protein S7p/S5e AAA_25 PF13481.6 AIN99637.1 - 0.029 14.0 0.1 2.9 7.4 0.0 3.4 4 0 0 4 4 4 0 AAA domain NTPase_1 PF03266.15 AIN99637.1 - 0.031 14.2 0.0 5.3 6.9 0.0 2.8 2 0 0 2 2 2 0 NTPase AAA_29 PF13555.6 AIN99637.1 - 0.039 13.7 0.0 10 5.9 0.0 2.7 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_6 PF12774.7 AIN99637.1 - 0.044 12.8 0.0 0.23 10.4 0.0 2.2 2 0 0 2 2 2 0 Hydrolytic ATP binding site of dynein motor region ABC_tran PF00005.27 AIN99637.1 - 0.049 14.1 1.7 10 6.7 0.0 3.3 3 1 0 3 3 3 0 ABC transporter ATP_bind_1 PF03029.17 AIN99637.1 - 0.12 12.2 0.0 5 6.8 0.0 2.6 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein WSD PF15613.6 AIN99637.1 - 0.69 10.4 3.1 1.5 9.3 3.1 1.6 1 0 0 1 1 1 0 Williams-Beuren syndrome DDT (WSD), D-TOX E motif AAA_17 PF13207.6 AIN99637.1 - 0.99 9.8 5.6 10 6.6 0.0 4.0 4 1 1 5 5 4 0 AAA domain AAA_23 PF13476.6 AIN99637.1 - 8.9 6.8 13.5 19 5.7 0.0 3.2 2 1 0 2 2 1 0 AAA domain Peptidase_M3 PF01432.20 AIN99638.1 - 1.2e-96 324.8 0.0 1.3e-96 324.7 0.0 1.0 1 0 0 1 1 1 1 Peptidase family M3 Peptidase_M50B PF13398.6 AIN99638.1 - 0.05 13.2 0.0 0.085 12.5 0.0 1.3 1 0 0 1 1 1 0 Peptidase M50B-like Methyltransf_25 PF13649.6 AIN99639.1 - 0.057 14.1 0.0 0.14 12.9 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain AAA PF00004.29 AIN99641.1 - 5.8e-10 39.7 0.0 4.4e-09 36.9 0.0 2.3 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 AIN99641.1 - 8.3e-08 32.6 0.1 8e-07 29.4 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 AIN99641.1 - 1.4e-06 28.8 0.0 1.8e-05 25.2 0.0 2.5 1 1 0 1 1 1 1 AAA ATPase domain AAA_19 PF13245.6 AIN99641.1 - 0.0031 17.9 0.0 0.014 15.8 0.0 2.1 1 1 0 1 1 1 1 AAA domain T2SSE PF00437.20 AIN99641.1 - 0.0063 15.6 0.0 0.022 13.8 0.0 1.8 2 0 0 2 2 2 1 Type II/IV secretion system protein ATPase_2 PF01637.18 AIN99641.1 - 0.0087 16.0 0.0 0.12 12.3 0.0 2.1 1 1 0 1 1 1 1 ATPase domain predominantly from Archaea NACHT PF05729.12 AIN99641.1 - 0.012 15.5 0.0 0.025 14.5 0.0 1.6 1 0 0 1 1 1 0 NACHT domain AAA_11 PF13086.6 AIN99641.1 - 0.02 14.7 0.0 0.046 13.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain DUF2075 PF09848.9 AIN99641.1 - 0.028 13.7 0.0 0.048 12.9 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_30 PF13604.6 AIN99641.1 - 0.042 13.6 0.1 0.25 11.1 0.0 2.3 1 1 1 2 2 2 0 AAA domain NB-ARC PF00931.22 AIN99641.1 - 0.059 12.5 0.0 0.1 11.8 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain PPR PF01535.20 AIN99642.1 - 3.6e-06 26.9 0.0 3.1 8.2 0.0 5.9 6 0 0 6 6 6 2 PPR repeat DUF2000 PF09391.10 AIN99642.1 - 0.051 13.5 0.4 0.18 11.7 0.4 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2000) PPR_2 PF13041.6 AIN99642.1 - 0.065 13.4 1.6 2.9 8.2 0.0 4.4 6 0 0 6 6 6 0 PPR repeat family AAA_lid_4 PF17864.1 AIN99642.1 - 0.15 11.9 0.5 1.2 8.9 0.0 2.8 2 0 0 2 2 2 0 RuvB AAA lid domain NYD-SP28 PF14772.6 AIN99643.1 - 1.3e-15 57.2 4.4 1.3e-15 57.2 4.4 4.6 2 1 2 4 4 4 1 Sperm tail NYD-SP28_assoc PF14775.6 AIN99643.1 - 8.8e-05 22.5 0.9 0.00059 19.9 0.3 2.8 2 0 0 2 2 2 1 Sperm tail C-terminal domain DUF5521 PF17659.1 AIN99643.1 - 0.0032 15.4 0.0 0.0058 14.5 0.0 1.3 1 0 0 1 1 1 1 Family of unknown function (DUF5521) SOAR PF16533.5 AIN99643.1 - 0.0041 17.1 24.6 0.0055 16.7 1.9 3.6 1 1 2 3 3 3 2 STIM1 Orai1-activating region CVNH PF08881.10 AIN99643.1 - 0.42 11.3 2.4 2.9 8.6 1.3 2.8 2 1 0 2 2 2 0 CVNH domain FIST PF08495.10 AIN99644.1 - 0.00073 19.6 0.1 0.0014 18.7 0.1 1.6 1 0 0 1 1 1 1 FIST N domain DUF2550 PF10739.9 AIN99645.1 - 0.0076 16.2 0.3 0.039 13.9 0.1 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF2550) Ank_2 PF12796.7 AIN99646.1 - 5.1e-08 33.4 0.1 4.3e-06 27.2 0.0 2.8 1 1 1 2 2 2 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 AIN99646.1 - 0.00011 22.3 0.5 0.14 12.8 0.1 4.1 3 0 0 3 3 3 1 Ankyrin repeat Ank_4 PF13637.6 AIN99646.1 - 0.0033 18.0 0.2 0.026 15.1 0.1 2.8 1 1 2 3 3 3 2 Ankyrin repeats (many copies) IQ PF00612.27 AIN99646.1 - 0.0037 16.9 10.1 1.4 8.9 0.0 4.7 4 0 0 4 4 4 2 IQ calmodulin-binding motif Ank_5 PF13857.6 AIN99646.1 - 0.064 13.6 0.1 0.39 11.1 0.0 2.3 2 0 0 2 2 2 0 Ankyrin repeats (many copies) Ank PF00023.30 AIN99646.1 - 0.89 10.1 11.3 0.29 11.7 0.2 4.7 4 1 0 4 4 4 0 Ankyrin repeat Proteasome PF00227.26 AIN99648.1 - 2.4e-38 131.5 0.0 2.8e-38 131.3 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit TFIIS_C PF01096.18 AIN99649.1 - 0.00067 19.5 3.1 0.00067 19.5 3.1 3.1 3 1 0 3 3 3 1 Transcription factor S-II (TFIIS) zf-Sec23_Sec24 PF04810.15 AIN99649.1 - 0.0021 18.0 2.7 0.0021 18.0 2.7 1.9 2 0 0 2 2 2 1 Sec23/Sec24 zinc finger RNA_POL_M_15KD PF02150.16 AIN99649.1 - 0.0038 17.1 5.9 0.0038 17.1 5.9 2.8 3 0 0 3 3 3 1 RNA polymerases M/15 Kd subunit Ogr_Delta PF04606.12 AIN99649.1 - 0.015 15.3 2.3 0.015 15.3 2.3 2.4 2 2 0 2 2 2 0 Ogr/Delta-like zinc finger zf-ribbon_3 PF13248.6 AIN99649.1 - 0.27 10.7 10.7 3.3 7.3 1.1 3.7 4 0 0 4 4 4 0 zinc-ribbon domain HNH_5 PF14279.6 AIN99649.1 - 0.33 10.8 0.1 0.33 10.8 0.1 2.7 3 0 0 3 3 3 0 HNH endonuclease zinc_ribbon_2 PF13240.6 AIN99649.1 - 1.4 8.7 11.7 0.3 10.9 0.6 3.3 3 0 0 3 3 3 0 zinc-ribbon domain Nudix_N_2 PF14803.6 AIN99649.1 - 1.8 8.5 10.6 4.6 7.2 1.4 2.9 2 1 0 2 2 2 0 Nudix N-terminal Zn_Tnp_IS1595 PF12760.7 AIN99649.1 - 2.2 8.4 14.0 0.26 11.3 1.6 2.7 2 2 0 2 2 2 0 Transposase zinc-ribbon domain Zn_ribbon_recom PF13408.6 AIN99649.1 - 4.7 7.8 8.5 0.77 10.3 2.2 2.3 2 1 0 2 2 2 0 Recombinase zinc beta ribbon domain Lar_restr_allev PF14354.6 AIN99649.1 - 8 6.9 13.8 0.093 13.1 2.3 2.7 2 1 0 2 2 2 0 Restriction alleviation protein Lar Sugar_tr PF00083.24 AIN99650.1 - 0.15 10.8 10.4 1.6 7.5 9.5 1.9 1 1 0 1 1 1 0 Sugar (and other) transporter Fumble PF03630.14 AIN99651.1 - 6.5e-93 311.5 0.0 1.4e-92 310.5 0.0 1.5 1 0 0 1 1 1 1 Fumble AMP-binding PF00501.28 AIN99651.1 - 3.2e-13 49.1 0.3 2.3e-08 33.1 0.0 2.2 2 0 0 2 2 2 2 AMP-binding enzyme Exo_endo_phos PF03372.23 AIN99651.1 - 9.8e-08 31.8 0.0 1.8e-07 31.0 0.0 1.5 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Spo7_2_N PF15407.6 AIN99652.1 - 0.02 14.5 0.0 0.056 13.1 0.0 1.8 2 0 0 2 2 2 0 Sporulation protein family 7 RRM_1 PF00076.22 AIN99652.1 - 0.08 12.8 0.0 0.61 9.9 0.0 2.1 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 AIN99652.1 - 0.14 12.1 0.0 0.23 11.4 0.0 1.5 1 1 0 1 1 1 0 Occluded RNA-recognition motif DSPc PF00782.20 AIN99653.1 - 4.4e-24 84.8 0.0 7.8e-24 84.0 0.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain LRR_8 PF13855.6 AIN99653.1 - 1.6e-08 34.2 7.5 9.8e-05 22.0 2.0 3.7 3 0 0 3 3 3 3 Leucine rich repeat LRR_4 PF12799.7 AIN99653.1 - 3.9e-05 23.9 10.7 0.0023 18.3 4.5 3.9 3 1 1 4 4 4 2 Leucine Rich repeats (2 copies) Y_phosphatase PF00102.27 AIN99653.1 - 0.0048 16.5 0.0 0.0077 15.8 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase LRR_9 PF14580.6 AIN99653.1 - 0.028 13.9 2.1 3.5 7.1 0.0 2.4 2 0 0 2 2 2 0 Leucine-rich repeat Init_tRNA_PT PF04179.12 AIN99653.1 - 0.11 12.8 0.0 0.27 11.6 0.0 1.6 1 0 0 1 1 1 0 Rit1 DUSP-like domain CDKN3 PF05706.12 AIN99653.1 - 0.13 11.9 0.0 0.25 11.0 0.0 1.4 1 0 0 1 1 1 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) Histone PF00125.24 AIN99657.1 - 4.7e-12 46.4 0.1 6.1e-12 46.0 0.1 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 AIN99657.1 - 0.0097 16.2 0.3 0.023 15.0 0.3 1.6 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Cylicin_N PF15241.6 AIN99657.1 - 0.051 13.7 0.3 0.073 13.2 0.3 1.3 1 0 0 1 1 1 0 Cylicin N-terminus DHHC PF01529.20 AIN99658.1 - 2.8e-32 111.6 4.0 2.8e-32 111.6 4.0 2.0 2 0 0 2 2 2 1 DHHC palmitoyltransferase LapA_dom PF06305.11 AIN99658.1 - 0.04 13.7 0.2 0.12 12.2 0.2 1.8 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain AzlD PF05437.12 AIN99658.1 - 0.72 10.1 7.0 2.6 8.3 0.2 3.2 2 1 1 3 3 3 0 Branched-chain amino acid transport protein (AzlD) DAO PF01266.24 AIN99660.1 - 3.4e-42 145.3 0.2 6.2e-42 144.4 0.0 1.5 2 0 0 2 2 2 1 FAD dependent oxidoreductase DAO_C PF16901.5 AIN99660.1 - 9.4e-34 116.0 0.4 1.8e-33 115.1 0.4 1.5 1 0 0 1 1 1 1 C-terminal domain of alpha-glycerophosphate oxidase FAD_binding_2 PF00890.24 AIN99660.1 - 0.0098 15.0 1.3 0.019 14.1 1.3 1.5 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.7 AIN99660.1 - 0.019 14.3 1.8 0.033 13.5 1.8 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 AIN99660.1 - 0.035 13.3 0.2 0.15 11.3 0.1 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.18 AIN99660.1 - 0.069 13.0 0.2 0.19 11.6 0.2 1.8 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 AIN99660.1 - 0.069 12.4 0.0 0.2 11.0 0.0 1.8 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain GIDA PF01134.22 AIN99660.1 - 0.11 11.5 1.0 1.1 8.2 0.2 2.2 2 0 0 2 2 2 0 Glucose inhibited division protein A NADH-u_ox-rdase PF10785.9 AIN99661.1 - 1.2e-11 45.2 0.2 2.1e-11 44.3 0.2 1.5 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit PAPS_reduct PF01507.19 AIN99663.1 - 2.1e-22 80.0 0.0 7.6e-17 61.9 0.0 2.1 1 1 1 2 2 2 2 Phosphoadenosine phosphosulfate reductase family ATP_bind_3 PF01171.20 AIN99663.1 - 0.068 12.9 0.0 0.087 12.6 0.0 1.2 1 0 0 1 1 1 0 PP-loop family zf_CCCH_4 PF18345.1 AIN99666.1 - 2.4e-07 30.6 10.1 0.00018 21.4 3.4 2.8 2 0 0 2 2 2 2 Zinc finger domain zf-CCCH PF00642.24 AIN99666.1 - 6.9e-06 25.8 8.5 3.6e-05 23.5 0.6 2.9 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-HIT PF04438.16 AIN99666.1 - 7.3e-06 25.7 13.6 2.3e-05 24.2 13.6 1.9 1 0 0 1 1 1 1 HIT zinc finger Torus PF16131.5 AIN99666.1 - 0.00068 20.3 4.6 0.093 13.4 0.2 2.7 1 1 1 2 2 2 2 Torus domain zf-CCCH_4 PF18044.1 AIN99666.1 - 0.0085 15.9 1.6 0.0085 15.9 1.6 3.2 3 0 0 3 3 3 2 CCCH-type zinc finger zf-CCCH_2 PF14608.6 AIN99666.1 - 0.14 12.7 7.1 0.21 12.1 1.3 2.8 2 0 0 2 2 2 0 RNA-binding, Nab2-type zinc finger RNB PF00773.19 AIN99669.1 - 5.6e-94 315.1 0.0 9e-94 314.4 0.0 1.3 1 0 0 1 1 1 1 RNB domain OB_Dis3 PF17849.1 AIN99669.1 - 1.8e-20 72.8 0.0 3.6e-20 71.8 0.0 1.6 1 0 0 1 1 1 1 Dis3-like cold-shock domain 2 (CSD2) Rrp44_CSD1 PF17216.3 AIN99669.1 - 4.7e-09 36.1 0.0 1.2e-08 34.8 0.0 1.7 1 0 0 1 1 1 1 Rrp44-like cold shock domain CSD2 PF17876.1 AIN99669.1 - 2.7e-06 27.5 0.0 5.1e-05 23.4 0.0 2.6 2 0 0 2 2 2 1 Cold shock domain Rrp44_S1 PF17215.3 AIN99669.1 - 0.00092 19.1 0.1 0.0037 17.2 0.0 2.0 1 1 1 2 2 2 1 S1 domain Dis3l2_C_term PF17877.1 AIN99669.1 - 0.014 15.7 0.0 0.04 14.2 0.0 1.7 1 0 0 1 1 1 0 DIS3-like exonuclease 2 C terminal DUF3695 PF12494.8 AIN99669.1 - 0.07 13.0 0.0 0.15 12.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3695) MtN3_slv PF03083.16 AIN99671.1 - 9.7e-21 73.6 10.1 3.9e-12 46.0 1.6 2.4 2 0 0 2 2 2 2 Sugar efflux transporter for intercellular exchange Tox-ODYAM1 PF15642.6 AIN99671.1 - 0.023 13.7 0.1 0.031 13.3 0.1 1.1 1 0 0 1 1 1 0 Toxin in Odyssella and Amoebophilus ThiF PF00899.21 AIN99672.1 - 1.7e-08 34.2 0.1 2.7e-08 33.5 0.1 1.4 1 0 0 1 1 1 1 ThiF family Sacchrp_dh_NADP PF03435.18 AIN99674.1 - 1.7e-22 80.1 0.2 3.5e-22 79.0 0.2 1.6 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain NAD_binding_10 PF13460.6 AIN99674.1 - 5e-06 26.5 0.0 0.00052 20.0 0.0 2.3 1 1 1 2 2 2 2 NAD(P)H-binding 3Beta_HSD PF01073.19 AIN99674.1 - 0.0029 16.7 0.0 0.0047 16.0 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 AIN99674.1 - 0.0041 16.6 0.0 0.0069 15.9 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.24 AIN99674.1 - 0.0059 17.0 0.0 0.012 16.1 0.0 1.5 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain AAA PF00004.29 AIN99676.1 - 2.5e-40 138.0 0.0 5.4e-40 136.9 0.0 1.6 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 AIN99676.1 - 4.2e-10 39.3 0.3 1.6e-09 37.4 0.0 2.3 2 1 0 2 2 2 1 AAA+ lid domain Vps4_C PF09336.10 AIN99676.1 - 1.6e-08 34.4 0.4 5.1e-08 32.8 0.3 1.8 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain AAA_5 PF07728.14 AIN99676.1 - 1.6e-06 28.1 0.1 0.00064 19.7 0.0 3.5 4 1 0 4 4 4 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 AIN99676.1 - 8.5e-06 25.6 0.0 2.1e-05 24.3 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 AIN99676.1 - 0.00016 22.1 0.0 0.0006 20.2 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 AIN99676.1 - 0.00028 21.2 0.1 0.0092 16.3 0.1 2.5 1 1 1 2 2 2 1 AAA domain AAA_25 PF13481.6 AIN99676.1 - 0.00077 19.1 0.2 0.064 12.8 0.1 2.5 1 1 1 2 2 2 1 AAA domain AAA_24 PF13479.6 AIN99676.1 - 0.0014 18.4 0.0 0.0032 17.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 AIN99676.1 - 0.0019 18.8 0.4 0.006 17.1 0.0 2.1 3 0 0 3 3 1 1 AAA domain AAA_14 PF13173.6 AIN99676.1 - 0.0022 18.0 0.0 0.006 16.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 AIN99676.1 - 0.0023 17.3 0.0 0.0049 16.3 0.0 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI NACHT PF05729.12 AIN99676.1 - 0.0027 17.7 0.1 0.074 13.0 0.0 2.7 3 0 0 3 3 3 1 NACHT domain ATPase PF06745.13 AIN99676.1 - 0.0034 16.8 0.1 1.1 8.5 0.0 2.7 2 1 1 3 3 3 1 KaiC AAA_2 PF07724.14 AIN99676.1 - 0.0075 16.4 0.0 0.03 14.5 0.0 2.1 2 1 0 2 2 1 1 AAA domain (Cdc48 subfamily) TIP49 PF06068.13 AIN99676.1 - 0.0076 15.5 0.0 0.014 14.6 0.0 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain IstB_IS21 PF01695.17 AIN99676.1 - 0.0081 15.9 0.0 0.019 14.7 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_7 PF12775.7 AIN99676.1 - 0.015 14.8 0.0 0.03 13.8 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region RNA_helicase PF00910.22 AIN99676.1 - 0.016 15.6 0.0 0.04 14.3 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA_33 PF13671.6 AIN99676.1 - 0.016 15.4 0.0 0.042 14.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain Parvo_NS1 PF01057.17 AIN99676.1 - 0.041 13.0 0.5 0.12 11.5 0.0 1.8 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 TsaE PF02367.17 AIN99676.1 - 0.053 13.5 0.0 0.1 12.6 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE DUF815 PF05673.13 AIN99676.1 - 0.081 12.1 0.0 0.14 11.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_28 PF13521.6 AIN99676.1 - 0.095 12.9 0.0 0.21 11.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.26 AIN99676.1 - 0.12 12.1 0.0 0.53 10.0 0.0 2.0 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_3 PF07726.11 AIN99676.1 - 0.13 12.1 0.0 0.28 11.1 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 AIN99676.1 - 0.16 11.4 0.0 0.32 10.4 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein DUF4635 PF15466.6 AIN99676.1 - 0.16 11.4 0.0 0.41 10.2 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4635) ABC_tran PF00005.27 AIN99676.1 - 0.17 12.4 0.0 0.32 11.5 0.0 1.5 1 0 0 1 1 1 0 ABC transporter AAA_17 PF13207.6 AIN99676.1 - 0.17 12.3 0.6 0.77 10.2 0.0 2.3 3 0 0 3 3 2 0 AAA domain Carn_acyltransf PF00755.20 AIN99678.1 - 0.00032 19.5 0.0 0.00049 18.9 0.0 1.1 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase RNB PF00773.19 AIN99679.1 - 1.1e-88 297.7 0.0 1.4e-88 297.4 0.0 1.1 1 0 0 1 1 1 1 RNB domain WD40 PF00400.32 AIN99681.1 - 0.034 15.0 0.5 29 5.7 0.1 4.5 3 1 0 3 3 3 0 WD domain, G-beta repeat WD40_3 PF15911.5 AIN99681.1 - 0.069 13.2 0.0 15 5.7 0.0 4.0 4 0 0 4 4 4 0 WD domain, G-beta repeat Carb_anhydrase PF00194.21 AIN99682.1 - 7.4e-29 101.0 0.0 1.2e-28 100.4 0.0 1.3 1 0 0 1 1 1 1 Eukaryotic-type carbonic anhydrase Presenilin PF01080.17 AIN99682.1 - 0.63 8.7 5.5 1 8.0 5.5 1.3 1 0 0 1 1 1 0 Presenilin Mucin PF01456.17 AIN99682.1 - 0.97 9.4 23.1 0.33 11.0 17.0 2.5 2 0 0 2 2 2 0 Mucin-like glycoprotein Apt1 PF10351.9 AIN99682.1 - 3.8 6.2 11.2 6.6 5.5 11.2 1.3 1 0 0 1 1 1 0 Golgi-body localisation protein domain SOG2 PF10428.9 AIN99682.1 - 4.7 6.3 21.1 8.1 5.5 21.1 1.3 1 0 0 1 1 1 0 RAM signalling pathway protein Carboxyl_trans PF01039.22 AIN99684.1 - 8.1e-175 582.2 0.0 9.3e-175 582.0 0.0 1.0 1 0 0 1 1 1 1 Carboxyl transferase domain MdcE PF06833.11 AIN99684.1 - 0.0011 18.5 0.0 0.0026 17.3 0.0 1.6 1 0 0 1 1 1 1 Malonate decarboxylase gamma subunit (MdcE) ACCA PF03255.14 AIN99684.1 - 0.089 12.7 0.1 0.77 9.6 0.0 2.3 2 0 0 2 2 2 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit TPR_2 PF07719.17 AIN99685.1 - 1.7e-07 30.8 0.0 0.91 9.8 0.1 3.8 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.28 AIN99685.1 - 9.4e-07 28.4 0.7 0.5 10.3 0.0 3.7 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_16 PF13432.6 AIN99685.1 - 7.9e-05 23.2 4.2 0.014 16.1 0.6 3.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 AIN99685.1 - 0.00045 20.5 1.4 0.24 11.7 0.3 3.5 4 0 0 4 4 4 1 Tetratricopeptide repeat zf-MYND PF01753.18 AIN99685.1 - 0.0088 16.1 8.2 0.022 14.8 8.2 1.8 1 0 0 1 1 1 1 MYND finger TPR_19 PF14559.6 AIN99685.1 - 0.051 14.1 0.3 4 8.0 0.2 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF2560 PF10834.8 AIN99685.1 - 0.062 13.5 0.0 0.23 11.7 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2560) Pkinase PF00069.25 AIN99687.1 - 1.8e-62 211.1 0.0 2e-62 210.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 AIN99687.1 - 2e-38 132.1 0.0 2.5e-38 131.9 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 AIN99687.1 - 2.4e-06 27.1 0.0 3.4e-06 26.6 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 AIN99687.1 - 0.00027 20.0 0.1 0.00043 19.3 0.1 1.3 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 AIN99687.1 - 0.0044 17.0 1.3 0.026 14.5 0.6 2.2 1 1 0 2 2 2 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 AIN99687.1 - 0.0045 15.8 0.0 0.0063 15.3 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase FTA2 PF13095.6 AIN99687.1 - 0.0055 16.3 0.1 0.83 9.2 0.0 2.2 2 0 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 Seadorna_VP7 PF07387.11 AIN99687.1 - 0.024 13.7 0.0 0.039 13.0 0.0 1.4 1 0 0 1 1 1 0 Seadornavirus VP7 Kdo PF06293.14 AIN99687.1 - 0.025 13.9 0.1 0.044 13.1 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.9 AIN99687.1 - 0.037 13.5 0.0 0.069 12.7 0.0 1.3 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL GP52 PF17468.2 AIN99687.1 - 0.12 12.6 0.0 0.43 10.8 0.0 1.9 1 0 0 1 1 1 0 Phage gene product 52 AAA_23 PF13476.6 AIN99688.1 - 1.8e-27 97.1 0.0 1.8e-27 97.1 0.0 6.1 3 2 1 4 4 2 1 AAA domain SMC_N PF02463.19 AIN99688.1 - 3e-15 56.3 0.0 1.4e-07 31.2 0.0 2.3 2 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_15 PF13175.6 AIN99688.1 - 3.3e-11 43.5 3.0 4.7e-05 23.3 0.4 2.6 2 0 0 2 2 2 2 AAA ATPase domain AAA_21 PF13304.6 AIN99688.1 - 4.5e-08 33.3 0.1 0.0011 18.9 0.0 2.4 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SbcCD_C PF13558.6 AIN99688.1 - 1.9e-07 31.2 0.0 6.4e-07 29.5 0.0 1.9 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit ABC_tran PF00005.27 AIN99688.1 - 0.0012 19.3 14.4 0.0038 17.7 0.0 4.9 4 2 0 4 4 4 2 ABC transporter AAA_29 PF13555.6 AIN99688.1 - 0.0018 18.0 0.0 0.004 16.9 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain cobW PF02492.19 AIN99688.1 - 0.018 14.6 0.5 0.48 10.0 0.0 3.0 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Rad50_zn_hook PF04423.14 AIN99688.1 - 0.043 13.7 0.0 0.48 10.3 0.0 3.0 1 0 0 1 1 1 0 Rad50 zinc hook motif RsgA_GTPase PF03193.16 AIN99688.1 - 0.079 12.9 1.4 0.47 10.3 0.0 3.2 3 0 0 3 3 3 0 RsgA GTPase zf-C2H2_6 PF13912.6 AIN99688.1 - 0.1 12.7 1.1 0.55 10.3 0.0 2.9 3 0 0 3 3 3 0 C2H2-type zinc finger Octopine_DH PF02317.17 AIN99688.1 - 0.53 10.4 4.0 1.5 8.9 0.1 3.6 3 0 0 3 3 3 0 NAD/NADP octopine/nopaline dehydrogenase, alpha-helical domain Ribosomal_S26e PF01283.19 AIN99689.1 - 8.6e-36 122.7 3.6 9.1e-36 122.6 3.6 1.0 1 0 0 1 1 1 1 Ribosomal protein S26e Rad51 PF08423.11 AIN99690.1 - 2.6e-128 426.7 0.3 4.1e-128 426.0 0.2 1.4 2 0 0 2 2 2 1 Rad51 AAA_25 PF13481.6 AIN99690.1 - 4.4e-11 42.7 0.1 6.8e-11 42.1 0.1 1.2 1 0 0 1 1 1 1 AAA domain RecA PF00154.21 AIN99690.1 - 2.6e-10 40.2 0.1 4.2e-10 39.5 0.1 1.3 1 0 0 1 1 1 1 recA bacterial DNA recombination protein HHH_5 PF14520.6 AIN99690.1 - 4e-05 24.1 0.1 0.00012 22.6 0.1 1.9 1 0 0 1 1 1 1 Helix-hairpin-helix domain ATPase PF06745.13 AIN99690.1 - 0.00022 20.7 0.7 0.00085 18.7 0.7 1.9 1 1 0 1 1 1 1 KaiC DnaB_C PF03796.15 AIN99690.1 - 0.0037 16.7 0.1 0.016 14.6 0.0 1.9 2 1 0 2 2 2 1 DnaB-like helicase C terminal domain AAA_22 PF13401.6 AIN99690.1 - 0.021 15.1 0.0 0.044 14.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain PAXNEB PF05625.11 AIN99690.1 - 0.21 10.7 0.1 0.74 8.9 0.0 1.8 2 0 0 2 2 2 0 PAXNEB protein Nucleoside_tran PF01733.18 AIN99691.1 - 4.6e-33 114.9 9.7 3.8e-32 111.9 9.7 2.2 1 1 0 1 1 1 1 Nucleoside transporter UL45 PF05473.12 AIN99691.1 - 2.1 7.9 4.6 16 5.1 0.2 2.8 2 0 0 2 2 2 0 UL45 protein, carbohydrate-binding C-type lectin-like Stevor PF17410.2 AIN99691.1 - 5.1 6.6 4.9 9.9 5.6 4.9 1.4 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame Mod_r PF07200.13 AIN99692.1 - 6.7e-08 32.8 1.3 6.9e-08 32.7 0.3 1.5 2 0 0 2 2 1 1 Modifier of rudimentary (Mod(r)) protein Csm1_N PF18504.1 AIN99692.1 - 0.0034 17.7 2.8 0.0034 17.7 2.8 2.5 2 1 1 3 3 3 1 Csm1 N-terminal domain ADIP PF11559.8 AIN99692.1 - 0.039 14.0 3.0 0.15 12.2 3.0 1.9 1 1 0 1 1 1 0 Afadin- and alpha -actinin-Binding TMCO5 PF14992.6 AIN99692.1 - 0.043 13.4 1.3 0.059 12.9 1.3 1.2 1 0 0 1 1 1 0 TMCO5 family TSC22 PF01166.18 AIN99692.1 - 0.043 14.1 0.8 1.6 9.1 0.4 3.0 1 1 1 2 2 2 0 TSC-22/dip/bun family CENP-H PF05837.12 AIN99692.1 - 0.056 13.9 1.6 0.13 12.7 1.6 1.6 1 0 0 1 1 1 0 Centromere protein H (CENP-H) JIP_LZII PF16471.5 AIN99692.1 - 0.066 13.4 2.0 0.16 12.2 2.0 1.6 1 0 0 1 1 1 0 JNK-interacting protein leucine zipper II APG6_N PF17675.1 AIN99692.1 - 0.076 13.5 1.1 0.29 11.6 0.2 2.2 2 0 0 2 2 2 0 Apg6 coiled-coil region DUF4201 PF13870.6 AIN99692.1 - 0.082 12.6 4.4 0.05 13.3 2.1 1.8 2 1 0 2 2 2 0 Domain of unknown function (DUF4201) Lectin_N PF03954.14 AIN99692.1 - 0.097 12.4 1.9 0.16 11.7 0.3 2.0 2 0 0 2 2 2 0 Hepatic lectin, N-terminal domain bZIP_2 PF07716.15 AIN99692.1 - 0.16 12.1 4.2 0.14 12.3 1.2 2.4 1 1 1 2 2 2 0 Basic region leucine zipper Syntaxin_2 PF14523.6 AIN99692.1 - 0.17 12.2 2.7 1.6 9.2 2.7 2.6 1 1 0 1 1 1 0 Syntaxin-like protein Fib_alpha PF08702.10 AIN99692.1 - 0.18 12.0 5.6 0.31 11.2 0.7 2.8 3 0 0 3 3 3 0 Fibrinogen alpha/beta chain family ZapB PF06005.12 AIN99692.1 - 0.21 12.1 5.5 0.076 13.5 2.6 1.8 2 0 0 2 2 1 0 Cell division protein ZapB GAS PF13851.6 AIN99692.1 - 0.22 10.9 6.1 0.37 10.1 2.5 2.2 1 1 0 2 2 2 0 Growth-arrest specific micro-tubule binding Cnn_1N PF07989.11 AIN99692.1 - 0.3 11.3 5.2 0.11 12.6 1.3 2.2 2 1 1 3 3 2 0 Centrosomin N-terminal motif 1 Fungal_TACC PF12709.7 AIN99692.1 - 0.39 11.2 2.9 0.28 11.6 0.9 1.8 2 0 0 2 2 1 0 Fungal Transforming acidic coiled-coil (TACC) proteins Seryl_tRNA_N PF02403.22 AIN99692.1 - 0.39 11.0 3.2 0.26 11.5 0.7 1.9 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain FlaC_arch PF05377.11 AIN99692.1 - 0.48 10.8 6.1 0.75 10.2 2.4 3.0 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) DUF948 PF06103.11 AIN99692.1 - 0.66 10.3 4.1 0.57 10.5 1.7 2.2 2 1 1 3 3 2 0 Bacterial protein of unknown function (DUF948) DivIC PF04977.15 AIN99692.1 - 1.2 8.9 5.3 0.57 10.0 2.1 2.1 2 1 0 2 2 2 0 Septum formation initiator DUF1664 PF07889.12 AIN99692.1 - 2.8 8.0 5.6 0.93 9.5 1.7 2.1 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) Pkinase PF00069.25 AIN99693.1 - 3e-54 184.1 0.0 1e-36 126.6 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 AIN99693.1 - 9.1e-22 77.6 0.0 8.3e-20 71.2 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.23 AIN99693.1 - 0.0064 16.4 0.1 0.03 14.2 0.0 1.8 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 AIN99693.1 - 0.018 14.4 0.0 0.033 13.5 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 AIN99693.1 - 0.1 11.5 0.0 0.42 9.5 0.0 1.8 1 1 0 1 1 1 0 Haspin like kinase domain Kinase-like PF14531.6 AIN99693.1 - 0.13 11.6 0.3 3.4 6.9 0.1 2.5 3 0 0 3 3 3 0 Kinase-like FTA2 PF13095.6 AIN99693.1 - 0.16 11.6 0.2 11 5.6 0.0 2.3 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 SlyX PF04102.12 AIN99694.1 - 0.011 16.4 10.4 1.7 9.3 4.5 3.4 3 0 0 3 3 3 0 SlyX Spc29 PF17082.5 AIN99694.1 - 0.057 13.3 1.6 0.12 12.2 1.0 1.7 1 1 0 1 1 1 0 Spindle Pole Component 29 Med9 PF07544.13 AIN99694.1 - 0.19 11.9 1.3 22 5.2 0.8 2.7 2 0 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 CENP-H PF05837.12 AIN99694.1 - 0.2 12.1 2.0 1.6 9.1 0.5 2.9 3 0 0 3 3 3 0 Centromere protein H (CENP-H) DUF5082 PF16888.5 AIN99694.1 - 0.24 11.7 4.0 7 7.0 1.9 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF5082) ATG16 PF08614.11 AIN99694.1 - 2.8 8.1 9.2 0.13 12.5 2.7 2.1 2 1 0 2 2 2 0 Autophagy protein 16 (ATG16) SSFA2_C PF14723.6 AIN99694.1 - 7.1 6.5 10.1 0.46 10.4 1.9 3.0 2 1 1 3 3 3 0 Sperm-specific antigen 2 C-terminus DUF3138 PF11336.8 AIN99694.1 - 8.8 4.8 6.6 1.6 7.3 0.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3138) DMAP1 PF05499.12 AIN99695.1 - 1.1 9.2 6.9 1.1 9.1 6.9 1.0 1 0 0 1 1 1 0 DNA methyltransferase 1-associated protein 1 (DMAP1) DUF2462 PF09495.10 AIN99695.1 - 1.3 9.8 14.4 0.16 12.7 9.1 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF2462) AAA_6 PF12774.7 AIN99696.1 - 2.7e-150 499.9 0.0 2.8e-149 496.5 0.0 2.5 3 0 0 3 3 3 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 AIN99696.1 - 2.2e-118 395.9 4.2 2.2e-118 395.9 4.2 2.8 2 0 0 2 2 2 1 Dynein heavy chain, N-terminal region 2 Dynein_C PF18199.1 AIN99696.1 - 9.5e-103 343.6 0.0 4e-102 341.5 0.0 2.2 2 0 0 2 2 2 1 Dynein heavy chain C-terminal domain AAA_8 PF12780.7 AIN99696.1 - 7.4e-90 300.8 0.0 1.5e-87 293.2 0.0 3.7 3 0 0 3 3 3 1 P-loop containing dynein motor region D4 AAA_9 PF12781.7 AIN99696.1 - 2.8e-81 271.9 2.8 2.8e-81 271.9 2.8 2.5 2 0 0 2 2 2 1 ATP-binding dynein motor region AAA_7 PF12775.7 AIN99696.1 - 3.8e-65 218.8 0.0 1.9e-59 200.2 0.0 4.1 4 0 0 4 4 3 2 P-loop containing dynein motor region AAA_lid_11 PF18198.1 AIN99696.1 - 2.2e-54 183.7 0.0 6e-54 182.3 0.0 1.8 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain Dynein_heavy PF03028.15 AIN99696.1 - 1e-45 154.6 1.3 5e-44 149.2 0.1 3.6 3 0 0 3 3 3 1 Dynein heavy chain region D6 P-loop domain MT PF12777.7 AIN99696.1 - 1.1e-45 156.2 3.5 1.9e-45 155.4 2.7 1.9 2 0 0 2 2 2 1 Microtubule-binding stalk of dynein motor AAA_lid_1 PF17857.1 AIN99696.1 - 3.9e-16 59.1 0.1 1.4e-15 57.4 0.1 2.0 1 0 0 1 1 1 1 AAA+ lid domain Dynein_AAA_lid PF17852.1 AIN99696.1 - 3e-15 56.5 0.0 3.2e-14 53.1 0.0 3.0 4 0 0 4 4 1 1 Dynein heavy chain AAA lid domain AAA_5 PF07728.14 AIN99696.1 - 2e-13 50.5 0.1 7.5e-05 22.7 0.0 5.9 4 2 0 4 4 4 2 AAA domain (dynein-related subfamily) RNA_helicase PF00910.22 AIN99696.1 - 8.3e-07 29.4 0.1 0.0062 16.9 0.0 3.7 4 0 0 4 4 3 2 RNA helicase AAA_22 PF13401.6 AIN99696.1 - 1.1e-05 25.8 6.5 0.36 11.1 0.0 5.0 5 0 0 5 5 4 2 AAA domain AAA_16 PF13191.6 AIN99696.1 - 1.4e-05 25.6 0.7 0.37 11.1 0.0 5.1 4 0 0 4 4 4 2 AAA ATPase domain AAA_18 PF13238.6 AIN99696.1 - 2.2e-05 25.0 0.2 0.22 12.0 0.0 4.1 4 0 0 4 4 2 2 AAA domain AAA PF00004.29 AIN99696.1 - 4.6e-05 23.9 0.1 1.5 9.2 0.0 4.4 4 0 0 4 4 3 1 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 AIN99696.1 - 6.3e-05 22.8 2.6 5 6.8 0.0 3.7 3 0 0 3 3 3 3 AAA domain T2SSE PF00437.20 AIN99696.1 - 0.012 14.7 5.6 0.3 10.1 0.1 4.3 6 0 0 6 6 6 0 Type II/IV secretion system protein AAA_24 PF13479.6 AIN99696.1 - 0.018 14.8 0.7 5.6 6.6 0.0 3.4 3 0 0 3 3 3 0 AAA domain IstB_IS21 PF01695.17 AIN99696.1 - 0.025 14.3 1.0 14 5.4 0.0 3.5 3 0 0 3 3 3 0 IstB-like ATP binding protein AAA_29 PF13555.6 AIN99696.1 - 0.037 13.8 0.7 0.78 9.5 0.0 3.1 4 0 0 4 4 2 0 P-loop containing region of AAA domain Baculo_PEP_C PF04513.12 AIN99696.1 - 0.067 13.2 6.2 6.3 6.8 0.1 5.1 5 0 0 5 5 5 0 Baculovirus polyhedron envelope protein, PEP, C terminus Rad17 PF03215.15 AIN99696.1 - 0.072 13.0 0.0 16 5.4 0.0 2.8 2 0 0 2 2 2 0 Rad17 P-loop domain PhoH PF02562.16 AIN99696.1 - 0.13 11.7 3.5 2.5 7.5 0.0 3.3 3 0 0 3 3 3 0 PhoH-like protein AAA_25 PF13481.6 AIN99696.1 - 0.15 11.7 1.2 30 4.1 0.0 3.8 3 0 0 3 3 3 0 AAA domain Mg_chelatase PF01078.21 AIN99696.1 - 0.17 11.3 3.7 1.2 8.5 0.0 3.7 4 0 0 4 4 4 0 Magnesium chelatase, subunit ChlI AAA_23 PF13476.6 AIN99696.1 - 0.36 11.3 0.0 0.36 11.3 0.0 5.4 6 0 0 6 6 4 0 AAA domain SRP54 PF00448.22 AIN99696.1 - 0.57 9.8 3.0 11 5.6 0.0 3.0 3 0 0 3 3 3 0 SRP54-type protein, GTPase domain AAA_33 PF13671.6 AIN99696.1 - 1.2 9.3 5.8 17 5.6 0.1 4.1 3 0 0 3 3 3 0 AAA domain Pkinase PF00069.25 AIN99697.1 - 1.4e-51 175.4 0.0 2.5e-51 174.6 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 AIN99697.1 - 4.3e-36 124.5 0.0 8.6e-36 123.5 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Chloroa_b-bind PF00504.21 AIN99697.1 - 0.098 13.2 0.0 0.36 11.3 0.0 1.9 2 0 0 2 2 2 0 Chlorophyll A-B binding protein ER_lumen_recept PF00810.18 AIN99698.1 - 1.8e-48 165.1 8.7 1.8e-48 165.1 8.7 1.6 2 0 0 2 2 2 1 ER lumen protein retaining receptor ATP_synt_H PF05493.13 AIN99699.1 - 5.2e-19 68.5 5.5 5.7e-19 68.3 5.5 1.0 1 0 0 1 1 1 1 ATP synthase subunit H Phage_holin_3_6 PF07332.11 AIN99699.1 - 0.35 10.9 4.7 0.38 10.8 4.7 1.1 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III WD40 PF00400.32 AIN99700.1 - 4.8e-12 46.2 7.5 0.00075 20.3 0.1 6.7 6 1 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 AIN99700.1 - 5.1e-11 42.7 0.0 0.0034 17.6 0.0 3.5 3 1 0 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 AIN99700.1 - 0.5 9.3 2.2 1.1 8.1 0.7 2.4 2 2 1 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein DUF5538 PF17692.1 AIN99702.1 - 0.1 12.7 0.0 0.41 10.7 0.0 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF5538) Ank_4 PF13637.6 AIN99703.1 - 1.7e-18 66.7 0.1 7.3e-08 32.8 0.0 3.2 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 AIN99703.1 - 1.3e-17 64.1 1.4 9.5e-12 45.4 0.2 1.9 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 AIN99703.1 - 6e-14 51.9 1.6 1.7e-07 31.4 0.2 2.7 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 AIN99703.1 - 8.8e-11 41.1 0.3 0.0008 19.7 0.1 3.5 4 0 0 4 4 4 2 Ankyrin repeat Ank PF00023.30 AIN99703.1 - 7.7e-07 29.3 0.1 0.013 15.9 0.1 3.2 3 0 0 3 3 3 2 Ankyrin repeat Metallophos PF00149.28 AIN99704.1 - 4.8e-37 128.4 0.1 6.4e-37 128.0 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 AIN99704.1 - 6e-17 61.8 0.8 1.1e-16 60.9 0.8 1.5 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain BTB_2 PF02214.22 AIN99705.1 - 1.9e-11 44.1 0.0 3.1e-11 43.5 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain DUF4539 PF15072.6 AIN99706.1 - 1.5e-13 50.6 0.0 2.1e-13 50.1 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4539) SNARE_assoc PF09335.11 AIN99707.1 - 3.3e-09 37.3 1.4 3.3e-09 37.3 1.4 3.0 2 0 0 2 2 2 1 SNARE associated Golgi protein EF-hand_5 PF13202.6 AIN99707.1 - 0.0005 19.4 0.0 0.0011 18.4 0.0 1.5 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.6 AIN99707.1 - 0.00062 19.5 0.0 0.0027 17.5 0.0 2.0 2 0 0 2 2 2 1 EF-hand domain EF-hand_1 PF00036.32 AIN99707.1 - 0.016 14.7 0.0 0.058 13.0 0.0 2.0 2 0 0 2 2 2 0 EF hand EF-hand_7 PF13499.6 AIN99707.1 - 0.14 12.6 0.0 0.32 11.5 0.0 1.5 1 0 0 1 1 1 0 EF-hand domain pair Sas10_Utp3 PF04000.15 AIN99708.1 - 8e-18 64.9 2.8 1.1e-17 64.4 1.2 2.1 2 0 0 2 2 2 1 Sas10/Utp3/C1D family Sas10 PF09368.10 AIN99708.1 - 6.8e-17 61.7 6.0 2e-16 60.2 6.0 1.8 1 0 0 1 1 1 1 Sas10 C-terminal domain Pec_lyase PF09492.10 AIN99709.1 - 0.11 11.8 0.1 0.13 11.6 0.1 1.0 1 0 0 1 1 1 0 Pectic acid lyase Crl PF07417.12 AIN99709.1 - 0.34 11.0 2.5 0.37 10.9 2.0 1.4 1 1 0 1 1 1 0 Sigma factor-binding transcriptional regulator Crl IclR PF01614.18 AIN99711.1 - 0.092 12.6 0.6 0.12 12.2 0.6 1.2 1 0 0 1 1 1 0 Bacterial transcriptional regulator SNF2_N PF00176.23 AIN99712.1 - 6.8e-52 176.3 0.0 6.3e-51 173.1 0.0 2.0 1 1 1 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.31 AIN99712.1 - 5.3e-17 62.2 0.5 1.7e-16 60.5 0.1 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain zf-RING_UBOX PF13445.6 AIN99712.1 - 6.4e-07 29.3 3.3 1.5e-06 28.1 3.3 1.7 1 0 0 1 1 1 1 RING-type zinc-finger ResIII PF04851.15 AIN99712.1 - 1.6e-06 28.2 0.3 7.1e-06 26.1 0.0 2.2 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit zf-RING_5 PF14634.6 AIN99712.1 - 6.5e-06 26.0 5.9 1.6e-05 24.7 5.9 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 AIN99712.1 - 7.5e-06 25.7 5.3 1.6e-05 24.7 5.3 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 AIN99712.1 - 1.1e-05 25.2 6.1 2.4e-05 24.1 6.1 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-4CXXC_R1 PF10497.9 AIN99712.1 - 9.7e-05 22.5 6.7 0.00024 21.3 6.7 1.6 1 0 0 1 1 1 1 Zinc-finger domain of monoamine-oxidase A repressor R1 zf-RING_2 PF13639.6 AIN99712.1 - 0.00012 22.4 6.3 0.00012 22.4 6.3 2.0 2 0 0 2 2 2 1 Ring finger domain ERCC3_RAD25_C PF16203.5 AIN99712.1 - 0.00042 19.6 0.5 0.00079 18.7 0.5 1.4 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase DEAD PF00270.29 AIN99712.1 - 0.0025 17.6 0.0 0.0054 16.5 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase zf-C3HC4_2 PF13923.6 AIN99712.1 - 0.0034 17.2 10.8 0.019 14.8 10.9 2.2 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 AIN99712.1 - 0.0048 16.7 6.0 0.013 15.4 6.0 1.8 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 AIN99712.1 - 0.0095 16.1 5.6 0.02 15.0 5.6 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING Sec20 PF03908.13 AIN99712.1 - 0.022 14.7 1.9 0.35 10.8 0.4 2.7 2 0 0 2 2 2 0 Sec20 zf-rbx1 PF12678.7 AIN99712.1 - 1.2 9.5 8.2 0.35 11.2 4.4 2.1 1 1 1 2 2 2 0 RING-H2 zinc finger domain PAP_assoc PF03828.19 AIN99715.1 - 6.3e-12 45.5 0.0 1.5e-11 44.3 0.0 1.7 1 0 0 1 1 1 1 Cid1 family poly A polymerase DSPc PF00782.20 AIN99716.1 - 1e-16 60.9 0.3 9.5e-16 57.8 0.2 2.6 1 1 1 2 2 2 1 Dual specificity phosphatase, catalytic domain EF-hand_7 PF13499.6 AIN99717.1 - 1.3e-14 54.4 1.5 3e-06 27.6 0.1 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 AIN99717.1 - 9.1e-13 46.8 2.8 2.6e-06 26.6 0.0 3.9 4 0 0 4 4 4 3 EF hand EF-hand_9 PF14658.6 AIN99717.1 - 1.5e-12 47.6 0.0 7.7e-11 42.2 0.0 2.2 2 0 0 2 2 2 1 EF-hand domain EF-hand_6 PF13405.6 AIN99717.1 - 4.3e-12 44.9 2.3 3.7e-06 26.4 0.0 3.4 3 0 0 3 3 3 2 EF-hand domain EF-hand_8 PF13833.6 AIN99717.1 - 1.4e-07 31.2 2.7 0.00076 19.3 0.1 3.8 2 1 2 4 4 4 4 EF-hand domain pair EF-hand_5 PF13202.6 AIN99717.1 - 4.2e-05 22.8 1.1 0.037 13.5 0.0 3.5 3 0 0 3 3 3 2 EF hand EFhand_Ca_insen PF08726.10 AIN99717.1 - 0.062 13.4 0.2 0.2 11.8 0.1 1.9 1 1 1 2 2 2 0 Ca2+ insensitive EF hand RNA_pol_Rpb8 PF03870.15 AIN99718.1 - 1.1e-35 122.8 0.0 1.3e-35 122.6 0.0 1.0 1 0 0 1 1 1 1 RNA polymerase Rpb8 RNA_pol_RpbG PF16992.5 AIN99718.1 - 0.0016 18.5 0.3 0.49 10.5 0.0 2.1 2 0 0 2 2 2 2 DNA-directed RNA polymerase, subunit G Myco_19_kDa PF05481.12 AIN99718.1 - 0.13 12.5 0.1 0.17 12.2 0.1 1.2 1 0 0 1 1 1 0 Mycobacterium 19 kDa lipoprotein antigen PP_kinase_C PF13090.6 AIN99719.1 - 0.15 11.5 0.0 0.31 10.5 0.0 1.4 1 0 0 1 1 1 0 Polyphosphate kinase C-terminal domain 2 Patatin PF01734.22 AIN99719.1 - 1.9 8.6 6.2 3.5 7.7 1.1 2.2 1 1 0 2 2 2 0 Patatin-like phospholipase CSD PF00313.22 AIN99721.1 - 9e-16 57.5 0.3 1.2e-15 57.1 0.3 1.2 1 0 0 1 1 1 1 'Cold-shock' DNA-binding domain Stm1_N PF09598.10 AIN99721.1 - 0.16 12.8 2.4 0.36 11.7 2.4 1.6 1 1 0 1 1 1 0 Stm1 DUF5318 PF17249.2 AIN99722.1 - 0.11 12.3 1.1 5 6.9 0.1 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5318) FXMRP1_C_core PF12235.8 AIN99723.1 - 0.066 13.9 3.8 0.1 13.2 3.8 1.3 1 0 0 1 1 1 0 Fragile X-related 1 protein core C terminal MCM PF00493.23 AIN99724.1 - 3.3e-93 310.9 0.0 5.2e-93 310.2 0.0 1.3 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 AIN99724.1 - 3.1e-36 124.0 0.2 5.4e-36 123.2 0.2 1.4 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 AIN99724.1 - 2.2e-27 95.3 0.1 5e-27 94.1 0.1 1.6 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 AIN99724.1 - 1.4e-09 38.4 0.9 1.4e-09 38.4 0.9 3.2 3 1 0 3 3 3 1 MCM N-terminal domain Mg_chelatase PF01078.21 AIN99724.1 - 1.2e-07 31.3 0.3 1.2e-05 24.8 0.0 2.7 2 1 1 3 3 3 1 Magnesium chelatase, subunit ChlI MCM2_N PF12619.8 AIN99724.1 - 5.3e-07 30.1 19.5 5.3e-07 30.1 19.5 2.6 3 0 0 3 3 2 1 Mini-chromosome maintenance protein 2 AAA_5 PF07728.14 AIN99724.1 - 4.5e-06 26.7 0.0 9.8e-06 25.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 AIN99724.1 - 0.00086 19.2 0.0 0.0066 16.3 0.0 2.2 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_lid_2 PF17863.1 AIN99724.1 - 0.0073 16.1 0.0 0.026 14.3 0.0 1.9 1 0 0 1 1 1 1 AAA lid domain AAA PF00004.29 AIN99724.1 - 0.024 15.1 0.0 0.067 13.6 0.0 1.8 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 AIN99724.1 - 0.11 12.3 0.0 0.44 10.2 0.0 1.9 1 1 0 1 1 1 0 Sigma-54 interaction domain Ribonuc_red_lgC PF02867.15 AIN99728.1 - 5.2e-182 606.0 0.0 6.8e-182 605.7 0.0 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, barrel domain Ribonuc_red_lgN PF00317.21 AIN99728.1 - 1.3e-22 79.6 0.1 3.5e-22 78.2 0.1 1.8 1 0 0 1 1 1 1 Ribonucleotide reductase, all-alpha domain ATP-cone PF03477.16 AIN99728.1 - 3.7e-11 43.4 0.0 8.2e-11 42.3 0.0 1.6 1 0 0 1 1 1 1 ATP cone domain Lebercilin PF15619.6 AIN99729.1 - 0.015 15.0 36.8 0.08 12.6 29.9 3.2 2 1 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease CEP63 PF17045.5 AIN99729.1 - 0.11 12.4 27.1 0.095 12.6 8.9 2.4 1 1 1 2 2 2 0 Centrosomal protein of 63 kDa GFA PF04828.14 AIN99729.1 - 0.16 12.4 0.4 0.53 10.6 0.1 2.1 2 0 0 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme Prismane PF03063.20 AIN99729.1 - 0.18 10.5 4.5 0.25 10.0 4.5 1.1 1 0 0 1 1 1 0 Prismane/CO dehydrogenase family Prominin PF05478.11 AIN99729.1 - 6.4 4.6 9.4 3.9 5.3 7.1 1.7 1 1 1 2 2 2 0 Prominin Exo_endo_phos PF03372.23 AIN99730.1 - 5.1e-05 22.9 0.3 2.2 7.7 0.2 3.8 3 1 0 3 3 3 3 Endonuclease/Exonuclease/phosphatase family EF-hand_1 PF00036.32 AIN99731.1 - 2.4e-07 29.8 2.3 0.0084 15.6 0.1 3.0 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.6 AIN99731.1 - 3.5e-07 29.6 1.0 0.011 15.6 0.1 3.0 3 0 0 3 3 3 2 EF-hand domain EF-hand_5 PF13202.6 AIN99731.1 - 3.7e-07 29.3 1.0 0.004 16.6 0.0 2.5 2 0 0 2 2 2 2 EF hand Dockerin_1 PF00404.18 AIN99731.1 - 1.7e-06 28.1 1.0 0.03 14.5 0.3 2.4 2 0 0 2 2 2 2 Dockerin type I domain EF-hand_8 PF13833.6 AIN99731.1 - 0.0001 22.1 0.1 0.1 12.5 0.1 3.4 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_7 PF13499.6 AIN99731.1 - 0.0001 22.6 0.1 0.0022 18.4 0.1 2.5 2 1 1 3 3 3 2 EF-hand domain pair FUN14 PF04930.15 AIN99731.1 - 0.017 15.6 0.5 0.038 14.4 0.6 1.6 1 1 1 2 2 2 0 FUN14 family adh_short PF00106.25 AIN99734.1 - 8.1e-14 51.5 0.0 4.8e-08 32.7 0.0 2.4 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 AIN99734.1 - 2.4e-11 43.6 0.0 9.2e-06 25.4 0.0 2.3 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase Tctex-1 PF03645.13 AIN99735.1 - 3.2e-24 85.1 0.3 3.7e-24 84.9 0.3 1.0 1 0 0 1 1 1 1 Tctex-1 family Ribosomal_S11 PF00411.19 AIN99736.1 - 3.3e-47 159.4 1.5 4.1e-47 159.1 1.5 1.1 1 0 0 1 1 1 1 Ribosomal protein S11 LSM PF01423.22 AIN99737.1 - 0.0024 17.5 0.0 0.0036 16.9 0.0 1.3 1 0 0 1 1 1 1 LSM domain LSM14 PF12701.7 AIN99737.1 - 0.0041 17.2 0.0 0.0067 16.5 0.0 1.3 1 0 0 1 1 1 1 Scd6-like Sm domain SM-ATX PF14438.6 AIN99737.1 - 0.025 14.7 0.1 0.05 13.7 0.1 1.6 1 1 1 2 2 2 0 Ataxin 2 SM domain DUF2642 PF10842.8 AIN99737.1 - 0.23 11.3 0.1 0.51 10.2 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2642) Serinc PF03348.15 AIN99739.1 - 1.7e-55 188.7 35.8 2.2e-54 185.1 35.8 1.9 1 1 0 1 1 1 1 Serine incorporator (Serinc) TctB PF07331.11 AIN99739.1 - 0.99 9.7 25.2 0.022 15.0 9.7 3.4 2 2 1 3 3 3 0 Tripartite tricarboxylate transporter TctB family Beta-lactamase PF00144.24 AIN99740.1 - 0.0076 15.5 0.7 0.36 10.0 0.5 2.4 2 0 0 2 2 2 2 Beta-lactamase Ribosomal_S10 PF00338.22 AIN99741.1 - 7.1e-24 83.9 0.3 8.3e-24 83.7 0.3 1.1 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e PPR PF01535.20 AIN99742.1 - 0.00011 22.2 3.4 0.13 12.6 0.0 5.5 7 0 0 7 7 7 1 PPR repeat PPR_2 PF13041.6 AIN99742.1 - 0.00025 21.2 0.0 0.56 10.5 0.0 4.7 7 0 0 7 7 7 1 PPR repeat family PPR_long PF17177.4 AIN99742.1 - 0.044 13.2 0.5 0.77 9.1 0.0 2.9 3 0 0 3 3 3 0 Pentacotripeptide-repeat region of PRORP PPR_3 PF13812.6 AIN99742.1 - 0.053 13.6 0.0 1.4 9.0 0.0 2.8 2 0 0 2 2 2 0 Pentatricopeptide repeat domain TPR_14 PF13428.6 AIN99742.1 - 3.2 8.8 23.9 7.5 7.7 0.2 7.4 7 2 2 9 9 9 0 Tetratricopeptide repeat FlxA PF14282.6 AIN99743.1 - 0.01 15.8 1.6 0.03 14.3 1.6 1.8 1 0 0 1 1 1 0 FlxA-like protein HMG_box_2 PF09011.10 AIN99747.1 - 0.00071 20.1 3.2 0.16 12.6 0.1 2.8 2 0 0 2 2 2 2 HMG-box domain HMG_box PF00505.19 AIN99747.1 - 0.11 12.9 0.8 9.7 6.7 0.1 2.5 2 0 0 2 2 2 0 HMG (high mobility group) box AT_hook PF02178.19 AIN99747.1 - 4.6 7.4 9.7 4.2 7.6 5.0 2.8 2 0 0 2 2 2 0 AT hook motif ATP-grasp_4 PF13535.6 AIN99748.1 - 2.4e-09 37.0 0.1 1.7e-07 30.9 0.1 2.4 2 0 0 2 2 2 1 ATP-grasp domain ATP-grasp_3 PF02655.14 AIN99748.1 - 1.4e-05 25.2 0.0 0.00014 21.9 0.0 2.2 2 0 0 2 2 2 1 ATP-grasp domain GARS_A PF01071.19 AIN99748.1 - 1.9e-05 24.6 0.1 3.6e-05 23.6 0.1 1.4 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain CPSase_L_D2 PF02786.17 AIN99748.1 - 0.00014 21.4 0.0 0.01 15.3 0.0 2.3 2 0 0 2 2 2 1 Carbamoyl-phosphate synthase L chain, ATP binding domain ATPgrasp_Ter PF15632.6 AIN99748.1 - 0.0052 16.5 0.0 3 7.6 0.0 2.7 2 0 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon ubiquitin PF00240.23 AIN99750.1 - 0.00011 21.8 0.1 0.00024 20.8 0.1 1.5 1 0 0 1 1 1 1 Ubiquitin family SP2 PF03014.14 AIN99750.1 - 0.016 13.6 3.6 0.032 12.7 3.6 1.4 1 0 0 1 1 1 0 Structural protein 2 DUF1287 PF06940.11 AIN99750.1 - 0.17 11.6 0.2 0.4 10.3 0.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1287) WD40 PF00400.32 AIN99751.1 - 3.2e-36 122.7 27.1 7.5e-05 23.4 0.0 10.4 10 0 0 10 10 10 8 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 AIN99751.1 - 5e-14 52.4 0.3 0.0096 16.2 0.0 6.3 5 2 2 7 7 7 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 AIN99751.1 - 7.1e-06 26.0 0.0 0.17 11.7 0.0 3.4 3 0 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 AIN99751.1 - 0.0006 19.2 1.5 0.3 10.3 0.6 3.7 3 1 1 4 4 4 1 WD40-like domain PQQ_3 PF13570.6 AIN99751.1 - 0.0048 17.4 7.5 1e+02 3.6 0.0 7.0 7 0 0 7 7 7 0 PQQ-like domain Gmad1 PF10647.9 AIN99751.1 - 0.054 13.2 0.2 8.2 6.1 0.2 2.8 2 1 0 2 2 2 0 Lipoprotein LpqB beta-propeller domain Nucleoporin_N PF08801.11 AIN99751.1 - 0.09 11.5 0.5 2.1 7.0 0.3 2.9 2 1 0 2 2 2 0 Nup133 N terminal like PD40 PF07676.12 AIN99751.1 - 0.14 12.1 0.1 14 5.8 0.0 3.4 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat WD40_3 PF15911.5 AIN99751.1 - 0.14 12.1 1.3 3.9 7.6 0.0 3.5 4 0 0 4 4 4 0 WD domain, G-beta repeat Amastin PF07344.11 AIN99752.1 - 0.00023 21.0 12.3 0.00031 20.6 12.0 1.3 1 1 0 1 1 1 1 Amastin surface glycoprotein PMP22_Claudin PF00822.20 AIN99752.1 - 0.0056 16.6 10.6 0.0081 16.0 10.6 1.3 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family Tetraspanin PF00335.20 AIN99752.1 - 1 9.0 17.7 0.45 10.2 15.1 1.7 1 1 1 2 2 2 0 Tetraspanin family Amastin PF07344.11 AIN99753.1 - 9.4e-32 110.0 25.8 2.7e-22 79.3 6.5 2.6 2 1 1 3 3 3 2 Amastin surface glycoprotein ETF_alpha PF00766.19 AIN99754.1 - 1.3e-35 121.3 1.6 1.5e-35 121.1 0.1 1.9 2 0 0 2 2 2 1 Electron transfer flavoprotein FAD-binding domain ETF PF01012.21 AIN99754.1 - 4.6e-30 104.9 6.7 7.4e-30 104.2 6.7 1.3 1 0 0 1 1 1 1 Electron transfer flavoprotein domain AMP-binding PF00501.28 AIN99755.1 - 3.8e-51 174.0 0.4 3.3e-49 167.6 0.0 2.8 3 0 0 3 3 3 2 AMP-binding enzyme AMP-binding_C PF13193.6 AIN99755.1 - 5.8e-09 36.8 0.4 1.5e-08 35.5 0.4 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain ATP-synt_C PF00137.21 AIN99757.1 - 9.4e-26 89.9 46.5 6.4e-19 68.0 13.6 3.1 3 0 0 3 3 3 2 ATP synthase subunit C LRR_6 PF13516.6 AIN99758.1 - 1.7e-08 33.8 10.8 0.04 14.0 0.0 6.4 6 0 0 6 6 6 3 Leucine Rich repeat LRR_4 PF12799.7 AIN99758.1 - 0.14 12.6 2.9 23 5.6 0.0 4.0 4 0 0 4 4 4 0 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 AIN99758.1 - 5.3 6.9 7.2 8.6 6.2 0.1 4.2 5 0 0 5 5 5 0 Leucine rich repeat PhnG PF06754.12 AIN99759.1 - 1.1 9.2 8.3 0.23 11.4 4.8 1.5 2 0 0 2 2 2 0 Phosphonate metabolism protein PhnG Copine PF07002.16 AIN99761.1 - 8.6e-66 221.5 0.0 1.4e-65 220.8 0.0 1.3 1 0 0 1 1 1 1 Copine C2 PF00168.30 AIN99761.1 - 6.3e-27 93.9 0.0 9.7e-14 51.5 0.0 2.3 2 0 0 2 2 2 2 C2 domain vWA-TerF-like PF10138.9 AIN99761.1 - 2.8e-05 24.3 0.0 4.6e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 vWA found in TerF C terminus VWA PF00092.28 AIN99761.1 - 0.017 15.4 0.0 0.029 14.6 0.0 1.3 1 0 0 1 1 1 0 von Willebrand factor type A domain HSP70 PF00012.20 AIN99762.1 - 1.9e-251 835.5 14.0 2.1e-251 835.3 14.0 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 AIN99762.1 - 1e-20 73.9 0.7 3.5e-18 65.5 0.1 2.2 2 0 0 2 2 2 2 MreB/Mbl protein FGGY_C PF02782.16 AIN99762.1 - 7.6e-05 22.5 0.0 0.00032 20.5 0.0 2.2 3 0 0 3 3 3 1 FGGY family of carbohydrate kinases, C-terminal domain Hydantoinase_A PF01968.18 AIN99762.1 - 0.0053 16.1 0.2 0.039 13.2 0.1 2.3 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase DUF357 PF04010.13 AIN99762.1 - 0.16 12.1 0.2 27 4.9 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF357) Enolase_N PF03952.16 AIN99762.1 - 0.39 10.9 3.5 3.7 7.7 0.4 3.2 2 2 1 3 3 3 0 Enolase, N-terminal domain WWE PF02825.20 AIN99764.1 - 0.0015 19.1 0.0 0.004 17.7 0.0 1.8 1 0 0 1 1 1 1 WWE domain Lipase_GDSL PF00657.22 AIN99764.1 - 0.12 12.3 0.0 0.24 11.4 0.0 1.5 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase BIV_Env PF05858.12 AIN99764.1 - 0.18 10.0 0.1 0.25 9.5 0.1 1.1 1 0 0 1 1 1 0 Bovine immunodeficiency virus surface protein (SU) SGL PF08450.12 AIN99765.1 - 1e-38 133.3 0.0 3.5e-38 131.6 0.0 1.9 1 1 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region FAD_binding_1 PF00667.20 AIN99766.1 - 3e-36 125.1 0.0 4.4e-36 124.5 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.25 AIN99766.1 - 9.4e-34 116.7 0.4 6.1e-33 114.0 0.3 2.2 2 0 0 2 2 2 1 Flavodoxin NAD_binding_1 PF00175.21 AIN99766.1 - 1.7e-12 48.0 0.0 5.8e-12 46.2 0.0 1.9 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain BILBO1_N PF18281.1 AIN99767.1 - 6.1e-27 93.9 0.1 6.1e-27 93.9 0.1 2.0 2 0 0 2 2 2 1 BILBO1 N-terminal domain DUF4201 PF13870.6 AIN99767.1 - 0.0087 15.8 7.3 0.0087 15.8 7.3 1.7 1 1 0 1 1 1 1 Domain of unknown function (DUF4201) Exonuc_VII_L PF02601.15 AIN99767.1 - 0.64 9.5 8.6 0.99 8.9 8.6 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit CwfJ_C_1 PF04677.15 AIN99768.1 - 0.071 13.0 0.3 0.13 12.1 0.3 1.5 1 0 0 1 1 1 0 Protein similar to CwfJ C-terminus 1 DnaJ PF00226.31 AIN99769.1 - 2.8e-16 59.4 0.9 5.8e-16 58.4 0.9 1.6 1 0 0 1 1 1 1 DnaJ domain PDZ_6 PF17820.1 AIN99769.1 - 0.086 12.7 0.0 0.73 9.7 0.0 2.3 2 0 0 2 2 2 0 PDZ domain Biopterin_H PF00351.21 AIN99770.1 - 4.2e-131 436.9 0.0 5.6e-131 436.5 0.0 1.1 1 0 0 1 1 1 1 Biopterin-dependent aromatic amino acid hydroxylase zf-C3HC4_2 PF13923.6 AIN99772.1 - 4.9e-07 29.5 11.0 8.5e-07 28.7 11.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 AIN99772.1 - 1.7e-05 24.6 7.3 2.8e-05 24.0 7.3 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.25 AIN99772.1 - 3.4e-05 23.6 8.4 5.8e-05 22.9 8.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 AIN99772.1 - 4e-05 23.4 6.4 6.4e-05 22.7 6.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 AIN99772.1 - 0.00015 21.7 11.2 0.0003 20.7 11.2 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_2 PF13639.6 AIN99772.1 - 0.00025 21.3 9.9 0.0004 20.6 9.9 1.4 1 0 0 1 1 1 1 Ring finger domain Prok-RING_4 PF14447.6 AIN99772.1 - 0.00044 20.1 7.6 0.00073 19.3 7.6 1.3 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 AIN99772.1 - 0.0015 18.6 12.6 0.0025 18.0 12.6 1.4 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING Con-6 PF10346.9 AIN99772.1 - 0.065 13.3 0.3 0.25 11.4 0.1 2.1 2 0 0 2 2 2 0 Conidiation protein 6 TF_Zn_Ribbon PF08271.12 AIN99772.1 - 0.4 10.2 3.7 2.6 7.7 0.3 2.4 2 0 0 2 2 2 0 TFIIB zinc-binding Baculo_IE-1 PF05290.11 AIN99772.1 - 0.49 10.3 3.7 0.25 11.3 0.3 2.0 2 0 0 2 2 2 0 Baculovirus immediate-early protein (IE-0) zf-RING_6 PF14835.6 AIN99772.1 - 0.62 10.0 5.7 1.5 8.8 5.7 1.6 1 1 0 1 1 1 0 zf-RING of BARD1-type protein FapA PF03961.13 AIN99772.1 - 1.1 7.7 5.5 2.1 6.8 5.5 1.4 1 0 0 1 1 1 0 Flagellar Assembly Protein A zf-HIT PF04438.16 AIN99772.1 - 1.5 8.8 7.2 1 9.3 3.0 2.2 2 0 0 2 2 2 0 HIT zinc finger DZR PF12773.7 AIN99772.1 - 3.7 7.7 7.5 19 5.4 7.7 1.9 1 1 0 1 1 1 0 Double zinc ribbon zf-C2H2 PF00096.26 AIN99772.1 - 4.5 7.9 0.0 4.5 7.9 0.0 2.8 3 0 0 3 3 2 0 Zinc finger, C2H2 type zf-RING_4 PF14570.6 AIN99772.1 - 5.9 6.8 8.0 12 5.8 8.0 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain CCDC-167 PF15188.6 AIN99772.1 - 6.6 7.2 13.8 2.1 8.7 3.7 3.3 2 1 1 3 3 3 0 Coiled-coil domain-containing protein 167 DEAD PF00270.29 AIN99773.1 - 3.4e-42 144.2 0.0 6e-42 143.4 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 AIN99773.1 - 3.1e-25 88.7 0.0 1.4e-24 86.5 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 AIN99773.1 - 1.1e-12 47.9 0.1 2.9e-12 46.6 0.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.15 AIN99773.1 - 5.1e-08 33.1 0.0 1.1e-07 32.0 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DUF2753 PF10952.8 AIN99773.1 - 0.0077 16.4 0.1 0.017 15.3 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2753) DUF3160 PF11369.8 AIN99773.1 - 0.024 13.1 0.1 0.042 12.3 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3160) UbiA PF01040.18 AIN99774.1 - 1.3e-37 129.5 17.7 1.3e-37 129.5 17.7 1.5 1 1 0 1 1 1 1 UbiA prenyltransferase family Hydrolase_3 PF08282.12 AIN99776.1 - 3e-28 99.2 0.0 2.1e-26 93.2 0.0 2.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase S6PP PF05116.13 AIN99776.1 - 2e-07 30.8 0.0 2.4e-06 27.3 0.0 2.1 2 0 0 2 2 2 1 Sucrose-6F-phosphate phosphohydrolase Hydrolase PF00702.26 AIN99776.1 - 0.11 12.7 0.0 0.22 11.8 0.0 1.6 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 AIN99777.1 - 5.9e-36 124.5 0.0 5.9e-35 121.2 0.0 2.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase S6PP PF05116.13 AIN99777.1 - 7.3e-09 35.5 0.0 2.1e-06 27.5 0.0 2.4 2 0 0 2 2 2 2 Sucrose-6F-phosphate phosphohydrolase Hydrolase PF00702.26 AIN99777.1 - 0.00035 20.9 3.6 0.056 13.7 1.2 2.4 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase DUF4438 PF14505.6 AIN99777.1 - 0.096 11.6 0.0 0.16 10.9 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4438) HAD PF12710.7 AIN99777.1 - 0.24 11.8 2.3 24 5.2 0.0 3.3 2 1 1 3 3 3 0 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 AIN99778.1 - 8.2e-52 176.5 0.0 1.2e-51 176.0 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase S6PP PF05116.13 AIN99778.1 - 4.1e-16 59.3 0.0 2.4e-07 30.6 0.0 2.2 2 0 0 2 2 2 2 Sucrose-6F-phosphate phosphohydrolase Hydrolase PF00702.26 AIN99778.1 - 1.1e-07 32.4 0.1 0.014 15.7 0.0 2.4 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase HAD PF12710.7 AIN99778.1 - 6.9e-05 23.3 0.9 0.031 14.7 0.0 2.9 2 1 1 3 3 3 1 haloacid dehalogenase-like hydrolase Bmp PF02608.14 AIN99778.1 - 0.029 13.4 0.0 0.22 10.5 0.0 2.0 2 0 0 2 2 2 0 ABC transporter substrate-binding protein PnrA-like Hydrolase_6 PF13344.6 AIN99778.1 - 0.037 14.1 0.0 0.14 12.3 0.0 2.1 1 1 0 1 1 1 0 Haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 AIN99778.1 - 0.062 13.4 0.2 12 5.9 0.0 2.7 3 0 0 3 3 3 0 Haloacid dehalogenase-like hydrolase Phage_holin_5_2 PF16079.5 AIN99778.1 - 0.079 13.3 0.2 0.15 12.4 0.2 1.4 1 0 0 1 1 1 0 Phage holin family Hol44, in holin superfamily V Hydrolase_3 PF08282.12 AIN99779.1 - 3.2e-50 171.2 0.0 3.8e-50 171.0 0.0 1.1 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase S6PP PF05116.13 AIN99779.1 - 8e-18 64.9 0.0 5.2e-09 36.0 0.0 2.1 2 0 0 2 2 2 2 Sucrose-6F-phosphate phosphohydrolase Hydrolase PF00702.26 AIN99779.1 - 3.2e-08 34.1 0.0 8.1e-08 32.8 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 AIN99779.1 - 0.00045 20.7 0.2 2.5 8.5 0.0 3.4 2 1 1 4 4 4 2 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.6 AIN99779.1 - 0.0064 16.6 0.0 0.026 14.7 0.0 2.1 2 1 0 2 2 2 1 Haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 AIN99779.1 - 0.029 14.4 0.0 1.3 9.1 0.1 2.6 2 1 1 3 3 3 0 Haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 AIN99780.1 - 3.1e-49 168.0 0.0 4.7e-33 115.0 0.0 2.1 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase S6PP PF05116.13 AIN99780.1 - 4e-16 59.3 0.0 4.4e-11 42.8 0.0 2.3 2 0 0 2 2 2 2 Sucrose-6F-phosphate phosphohydrolase Hydrolase PF00702.26 AIN99780.1 - 1.5e-09 38.5 0.0 0.0011 19.3 0.0 2.7 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase HAD PF12710.7 AIN99780.1 - 0.00034 21.1 0.0 0.18 12.2 0.0 2.4 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 AIN99780.1 - 0.0087 16.2 0.0 4.5 7.3 0.0 2.4 2 0 0 2 2 2 2 Haloacid dehalogenase-like hydrolase X PF00739.19 AIN99780.1 - 0.12 12.5 0.3 0.23 11.6 0.3 1.4 1 0 0 1 1 1 0 Trans-activation protein X Hydrolase_6 PF13344.6 AIN99780.1 - 0.13 12.4 0.0 0.29 11.3 0.0 1.6 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 AIN99781.1 - 8.4e-40 137.1 0.2 2.5e-22 79.9 0.1 3.7 3 1 0 3 3 3 3 haloacid dehalogenase-like hydrolase S6PP PF05116.13 AIN99781.1 - 3.9e-15 56.1 0.0 3e-08 33.5 0.0 2.2 2 0 0 2 2 2 2 Sucrose-6F-phosphate phosphohydrolase Hydrolase PF00702.26 AIN99781.1 - 0.0014 19.0 0.0 0.68 10.2 0.0 2.2 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase HAD PF12710.7 AIN99781.1 - 0.0092 16.4 0.0 5.2 7.4 0.0 2.4 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Amastin PF07344.11 AIN99782.1 - 8.2e-51 171.9 7.0 1.2e-50 171.4 7.0 1.2 1 0 0 1 1 1 1 Amastin surface glycoprotein Amastin PF07344.11 AIN99783.1 - 5.4e-35 120.5 12.7 9.5e-35 119.7 12.7 1.4 1 0 0 1 1 1 1 Amastin surface glycoprotein PEN-2 PF10251.9 AIN99783.1 - 0.002 18.5 0.2 0.002 18.5 0.2 1.9 2 0 0 2 2 2 1 Presenilin enhancer-2 subunit of gamma secretase Molydop_binding PF01568.21 AIN99783.1 - 0.083 12.9 0.1 0.2 11.7 0.1 1.6 1 0 0 1 1 1 0 Molydopterin dinucleotide binding domain SUR7 PF06687.12 AIN99783.1 - 5 6.7 14.6 6.5 6.3 12.5 2.0 1 1 1 2 2 2 0 SUR7/PalI family zf-CCCH_4 PF18044.1 AIN99784.1 - 7.4e-07 28.8 6.2 1.2e-06 28.2 6.2 1.3 1 0 0 1 1 1 1 CCCH-type zinc finger zf-CCCH PF00642.24 AIN99784.1 - 7.4e-06 25.7 6.2 1.7e-05 24.6 5.6 1.9 2 0 0 2 2 2 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 AIN99784.1 - 9.8e-05 22.3 6.6 0.00017 21.5 6.6 1.4 1 0 0 1 1 1 1 Zinc finger domain Torus PF16131.5 AIN99784.1 - 0.001 19.7 1.3 0.002 18.8 1.3 1.4 1 0 0 1 1 1 1 Torus domain zf-CCCH_2 PF14608.6 AIN99784.1 - 0.0018 18.7 6.6 0.0037 17.7 6.6 1.5 1 0 0 1 1 1 1 RNA-binding, Nab2-type zinc finger IMS PF00817.20 AIN99785.1 - 6.5e-35 120.3 0.1 1.2e-34 119.5 0.1 1.5 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.8 AIN99785.1 - 7.7e-11 42.7 0.4 1.6e-10 41.7 0.4 1.4 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.8 AIN99785.1 - 1.1e-05 25.5 0.0 2.5e-05 24.3 0.0 1.7 1 0 0 1 1 1 1 IMS family HHH motif IMS PF00817.20 AIN99786.1 - 3.3e-39 134.3 0.0 6.4e-39 133.3 0.0 1.5 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.8 AIN99786.1 - 5.2e-13 49.7 0.9 1.2e-12 48.5 0.2 1.9 2 0 0 2 2 2 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.8 AIN99786.1 - 0.00027 21.1 0.0 0.00077 19.7 0.0 1.9 1 0 0 1 1 1 1 IMS family HHH motif IMS PF00817.20 AIN99788.1 - 0.04 13.9 1.8 5.7 6.9 1.8 3.1 1 1 0 1 1 1 0 impB/mucB/samB family AAA PF00004.29 AIN99790.1 - 1.3e-31 109.7 0.0 1.8e-28 99.6 0.0 3.3 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 AIN99790.1 - 3.1e-11 43.9 1.8 1.2e-06 29.0 0.0 3.6 3 1 0 3 3 3 2 AAA ATPase domain AAA_22 PF13401.6 AIN99790.1 - 4.5e-08 33.5 0.0 0.00017 21.9 0.0 3.1 2 1 1 3 3 3 2 AAA domain AAA_5 PF07728.14 AIN99790.1 - 4.9e-08 33.1 0.0 4.2e-06 26.8 0.0 2.6 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.17 AIN99790.1 - 2.1e-07 30.9 0.0 0.00016 21.5 0.0 2.6 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_33 PF13671.6 AIN99790.1 - 3.6e-07 30.4 0.0 0.00067 19.8 0.0 2.8 2 1 0 2 2 2 2 AAA domain AAA_14 PF13173.6 AIN99790.1 - 4e-06 26.9 0.0 2.3e-05 24.4 0.0 2.0 2 0 0 2 2 2 1 AAA domain TniB PF05621.11 AIN99790.1 - 4.7e-06 26.1 0.0 0.012 15.0 0.0 3.3 3 0 0 3 3 3 2 Bacterial TniB protein RuvB_N PF05496.12 AIN99790.1 - 8.2e-06 25.6 0.0 3.3e-05 23.7 0.0 2.1 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain RNA_helicase PF00910.22 AIN99790.1 - 8.2e-06 26.2 0.0 0.0088 16.4 0.0 2.4 2 0 0 2 2 2 1 RNA helicase Mg_chelatase PF01078.21 AIN99790.1 - 7.3e-05 22.2 0.0 0.0022 17.4 0.0 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_7 PF12775.7 AIN99790.1 - 0.00017 21.2 0.0 0.018 14.6 0.0 2.5 2 0 0 2 2 2 1 P-loop containing dynein motor region DUF815 PF05673.13 AIN99790.1 - 0.00027 20.2 0.0 0.0045 16.2 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_2 PF07724.14 AIN99790.1 - 0.00088 19.4 0.0 0.025 14.7 0.0 2.3 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_25 PF13481.6 AIN99790.1 - 0.0012 18.4 0.1 0.016 14.8 0.0 2.5 2 1 1 3 3 2 1 AAA domain AAA_24 PF13479.6 AIN99790.1 - 0.0012 18.6 0.0 0.013 15.2 0.0 2.2 2 0 0 2 2 2 1 AAA domain TsaE PF02367.17 AIN99790.1 - 0.0021 18.1 0.0 0.15 12.1 0.0 2.5 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE TIP49 PF06068.13 AIN99790.1 - 0.0029 16.9 0.0 0.0054 16.0 0.0 1.3 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_18 PF13238.6 AIN99790.1 - 0.004 17.7 0.0 0.055 14.0 0.0 2.4 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 AIN99790.1 - 0.0071 16.3 0.0 0.055 13.4 0.0 2.4 2 0 0 2 2 2 1 NACHT domain ATPase_2 PF01637.18 AIN99790.1 - 0.0097 15.8 0.0 0.73 9.7 0.0 3.0 2 1 0 2 2 2 1 ATPase domain predominantly from Archaea AAA_29 PF13555.6 AIN99790.1 - 0.0099 15.6 0.0 1.7 8.5 0.0 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain T2SSE PF00437.20 AIN99790.1 - 0.019 14.1 0.0 1.5 7.8 0.0 2.9 3 1 0 3 3 2 0 Type II/IV secretion system protein MCM PF00493.23 AIN99790.1 - 0.019 14.0 0.0 0.17 11.0 0.0 2.1 2 0 0 2 2 2 0 MCM P-loop domain AAA_28 PF13521.6 AIN99790.1 - 0.021 15.1 0.0 0.27 11.5 0.0 2.7 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.27 AIN99790.1 - 0.024 15.2 0.0 0.13 12.8 0.0 2.1 2 0 0 2 2 2 0 ABC transporter Sigma54_activat PF00158.26 AIN99790.1 - 0.027 14.2 0.0 0.18 11.5 0.0 2.2 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_3 PF07726.11 AIN99790.1 - 0.036 13.9 0.0 0.077 12.9 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 AIN99790.1 - 0.037 13.5 0.0 0.1 12.1 0.0 1.7 1 0 0 1 1 1 0 PhoH-like protein Parvo_NS1 PF01057.17 AIN99790.1 - 0.047 12.8 0.0 0.11 11.6 0.0 1.5 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 CPT PF07931.12 AIN99790.1 - 0.059 13.2 0.1 2.1 8.2 0.0 3.0 4 0 0 4 4 4 0 Chloramphenicol phosphotransferase-like protein AAA_11 PF13086.6 AIN99790.1 - 0.067 13.0 0.0 0.34 10.7 0.0 2.0 2 0 0 2 2 2 0 AAA domain Guanylate_kin PF00625.21 AIN99790.1 - 0.078 12.7 0.0 0.26 10.9 0.0 1.8 2 0 0 2 2 2 0 Guanylate kinase AAA_30 PF13604.6 AIN99790.1 - 0.079 12.7 0.0 0.38 10.4 0.0 2.0 2 0 0 2 2 2 0 AAA domain Cytidylate_kin2 PF13189.6 AIN99790.1 - 0.081 13.1 0.0 0.2 11.8 0.0 1.6 1 0 0 1 1 1 0 Cytidylate kinase-like family AAA_19 PF13245.6 AIN99790.1 - 0.1 12.9 0.5 0.66 10.3 0.1 2.3 2 1 0 2 2 2 0 AAA domain Syntaxin PF00804.25 AIN99791.1 - 1.4e-25 90.2 14.3 1.4e-25 90.2 14.3 1.3 2 0 0 2 2 2 1 Syntaxin SNARE PF05739.19 AIN99791.1 - 4.9e-12 45.6 0.7 4.9e-12 45.6 0.7 2.6 2 0 0 2 2 2 1 SNARE domain ETRAMP PF09716.10 AIN99791.1 - 0.069 13.2 0.0 0.13 12.3 0.0 1.8 1 1 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) HECT_2 PF09814.9 AIN99791.1 - 0.081 11.8 3.1 0.11 11.3 3.1 1.1 1 0 0 1 1 1 0 HECT-like Ubiquitin-conjugating enzyme (E2)-binding KGK PF08872.10 AIN99791.1 - 0.12 12.9 3.0 0.6 10.6 0.5 2.4 1 1 1 2 2 2 0 KGK domain TssN PF17555.2 AIN99791.1 - 0.18 11.2 2.4 0.13 11.6 0.5 1.7 2 0 0 2 2 2 0 Type VI secretion system, TssN Syntaxin_2 PF14523.6 AIN99791.1 - 0.23 11.8 9.9 2.8 8.4 0.3 2.6 2 1 0 2 2 2 0 Syntaxin-like protein T2SSF PF00482.23 AIN99791.1 - 1.8 8.6 4.6 2.4 8.1 0.6 2.8 2 2 0 2 2 2 0 Type II secretion system (T2SS), protein F Fzo_mitofusin PF04799.13 AIN99791.1 - 6.4 6.3 10.3 1.6 8.3 0.4 2.7 1 1 2 3 3 3 0 fzo-like conserved region DUF423 PF04241.15 AIN99792.1 - 2.2e-17 63.0 1.5 3.2e-17 62.5 1.5 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF423) DUF423 PF04241.15 AIN99793.1 - 8.6e-18 64.3 0.5 1.2e-17 63.9 0.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF423) DUF423 PF04241.15 AIN99794.1 - 6.7e-21 74.3 3.3 1.1e-20 73.7 3.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF423) DUF3277 PF11681.8 AIN99794.1 - 0.11 12.4 0.0 0.13 12.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3277) MSP1_C PF07462.11 AIN99795.1 - 0.02 13.6 0.9 0.028 13.1 0.9 1.1 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus NPV_P10 PF05531.12 AIN99796.1 - 0.66 10.5 14.7 0.35 11.4 0.8 5.1 5 0 0 5 5 5 0 Nucleopolyhedrovirus P10 protein DEAD PF00270.29 AIN99797.1 - 1.9e-45 154.8 0.0 8e-45 152.7 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 AIN99797.1 - 1.2e-31 109.3 0.1 9.7e-31 106.4 0.1 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 AIN99797.1 - 0.00038 20.5 0.0 0.0025 17.8 0.0 2.0 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit CMS1 PF14617.6 AIN99797.1 - 0.0022 17.4 0.0 0.0049 16.3 0.0 1.5 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit ERCC3_RAD25_C PF16203.5 AIN99797.1 - 0.095 11.9 0.1 0.13 11.4 0.1 1.2 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase Tup_N PF08581.10 AIN99798.1 - 0.05 13.9 0.3 0.13 12.6 0.3 1.7 1 0 0 1 1 1 0 Tup N-terminal Coa1 PF08695.10 AIN99799.1 - 0.0027 17.4 0.0 0.01 15.6 0.0 1.9 2 0 0 2 2 2 1 Cytochrome oxidase complex assembly protein 1 DUF630 PF04783.12 AIN99800.1 - 0.019 15.1 0.7 0.13 12.4 0.3 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF630) Abhydrolase_1 PF00561.20 AIN99801.1 - 3.3e-16 59.7 0.1 4.6e-14 52.7 0.1 2.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 AIN99801.1 - 4.9e-16 58.7 0.0 8.2e-16 58.0 0.0 1.3 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 AIN99801.1 - 6.2e-11 43.3 0.2 7.9e-11 43.0 0.2 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 AIN99801.1 - 1.3e-05 24.8 0.1 0.0037 16.8 0.0 2.8 3 0 0 3 3 3 1 Prolyl oligopeptidase family Abhydrolase_2 PF02230.16 AIN99801.1 - 0.0005 19.9 0.0 0.0043 16.9 0.0 2.1 2 1 0 2 2 2 1 Phospholipase/Carboxylesterase DLH PF01738.18 AIN99801.1 - 0.0013 18.4 0.0 0.021 14.4 0.0 2.2 2 0 0 2 2 2 1 Dienelactone hydrolase family FSH1 PF03959.13 AIN99801.1 - 0.0013 18.4 0.0 0.0038 16.9 0.0 1.8 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Peptidase_S15 PF02129.18 AIN99801.1 - 0.0024 17.5 0.0 0.26 10.9 0.0 2.1 2 0 0 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_4 PF08386.10 AIN99801.1 - 0.0029 17.7 0.0 0.0054 16.8 0.0 1.4 1 0 0 1 1 1 1 TAP-like protein Ndr PF03096.14 AIN99801.1 - 0.0049 15.6 0.2 0.011 14.5 0.2 1.5 1 1 0 1 1 1 1 Ndr family BAAT_C PF08840.11 AIN99801.1 - 0.089 12.7 0.0 0.21 11.5 0.0 1.6 1 1 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal Esterase_phd PF10503.9 AIN99801.1 - 0.18 11.3 0.4 7.7 5.9 0.1 2.3 2 0 0 2 2 2 0 Esterase PHB depolymerase TPP_enzyme_N PF02776.18 AIN99802.1 - 6.6e-13 48.6 0.8 3.9e-12 46.1 0.0 2.2 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.21 AIN99802.1 - 2e-10 40.7 5.1 3.4e-09 36.7 1.4 3.3 2 1 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain PALP PF00291.25 AIN99802.1 - 0.026 14.0 0.5 0.099 12.0 0.5 1.8 2 0 0 2 2 2 0 Pyridoxal-phosphate dependent enzyme Kelch_3 PF13415.6 AIN99803.1 - 5.4e-17 61.6 0.6 1.4e-05 25.2 0.0 4.9 4 1 0 4 4 4 3 Galactose oxidase, central domain Kelch_6 PF13964.6 AIN99803.1 - 7.1e-13 48.3 0.1 0.0002 21.5 0.0 5.1 5 0 0 5 5 5 3 Kelch motif Kelch_4 PF13418.6 AIN99803.1 - 2.9e-11 43.2 0.5 0.00012 22.0 0.0 3.7 3 0 0 3 3 3 2 Galactose oxidase, central domain Kelch_5 PF13854.6 AIN99803.1 - 3.6e-10 39.6 1.1 8e-05 22.5 0.0 4.6 4 0 0 4 4 4 2 Kelch motif Kelch_1 PF01344.25 AIN99803.1 - 4.1e-09 35.9 3.7 0.00013 21.4 0.1 4.1 4 0 0 4 4 4 2 Kelch motif Kelch_2 PF07646.15 AIN99803.1 - 7.6e-09 35.2 3.2 0.0026 17.7 0.0 4.2 4 0 0 4 4 4 3 Kelch motif DUF2784 PF10861.8 AIN99803.1 - 0.11 12.5 0.0 0.25 11.4 0.0 1.5 1 0 0 1 1 1 0 Protein of Unknown function (DUF2784) Helicase_C_2 PF13307.6 AIN99804.1 - 3e-41 141.4 0.0 6.3e-41 140.4 0.0 1.5 1 0 0 1 1 1 1 Helicase C-terminal domain DEAD_2 PF06733.15 AIN99804.1 - 2.1e-37 128.5 0.0 9.1e-37 126.4 0.0 2.0 2 0 0 2 2 2 1 DEAD_2 DEAD PF00270.29 AIN99804.1 - 0.00042 20.1 0.0 0.16 11.7 0.0 2.5 2 0 0 2 2 2 2 DEAD/DEAH box helicase ResIII PF04851.15 AIN99804.1 - 0.001 19.1 0.0 0.36 10.8 0.0 2.5 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit HBB PF06777.11 AIN99804.1 - 0.2 11.3 0.0 0.4 10.3 0.0 1.4 1 0 0 1 1 1 0 Helical and beta-bridge domain DUF4510 PF14971.6 AIN99805.1 - 0.077 13.3 1.1 13 6.2 0.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4510) TruD PF01142.18 AIN99806.1 - 1.1e-30 106.9 0.0 1.1e-26 93.6 0.0 2.9 2 1 0 2 2 2 2 tRNA pseudouridine synthase D (TruD) ALF PF03752.13 AIN99806.1 - 7 6.7 6.4 2.3 8.3 0.2 3.2 3 0 0 3 3 3 0 Short repeats of unknown function DUF3342 PF11822.8 AIN99808.1 - 4.1e-38 129.5 0.0 8.8e-38 128.4 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3342) Pkinase PF00069.25 AIN99810.1 - 0.027 13.9 0.0 3.7 6.8 0.0 2.3 2 0 0 2 2 2 0 Protein kinase domain Pkinase_Tyr PF07714.17 AIN99810.1 - 0.2 10.9 0.0 4.1 6.6 0.0 2.2 2 0 0 2 2 2 0 Protein tyrosine kinase Pkinase PF00069.25 AIN99812.1 - 7.6e-64 215.6 0.0 1.1e-63 215.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 AIN99812.1 - 2.2e-34 118.9 0.0 3.3e-34 118.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Lipocalin_5 PF13924.6 AIN99812.1 - 3.9e-33 114.2 0.0 7e-33 113.4 0.0 1.4 1 0 0 1 1 1 1 Lipocalin-like domain PX PF00787.24 AIN99812.1 - 8.5e-14 51.5 0.3 1.9e-13 50.4 0.3 1.5 1 0 0 1 1 1 1 PX domain Kinase-like PF14531.6 AIN99812.1 - 0.00044 19.7 0.0 0.00075 18.9 0.0 1.2 1 0 0 1 1 1 1 Kinase-like FYVE PF01363.21 AIN99812.1 - 0.0012 18.9 4.9 0.0039 17.3 4.9 1.8 1 0 0 1 1 1 1 FYVE zinc finger APH PF01636.23 AIN99812.1 - 0.0016 18.4 2.2 0.0093 15.9 0.3 2.7 2 1 1 3 3 3 1 Phosphotransferase enzyme family Kdo PF06293.14 AIN99812.1 - 0.062 12.6 0.1 0.15 11.4 0.0 1.6 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 AIN99812.1 - 0.074 12.6 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 RIO1 family FTA2 PF13095.6 AIN99812.1 - 0.16 11.5 0.0 2.8 7.5 0.0 2.2 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Zf_RING PF16744.5 AIN99812.1 - 0.39 10.9 2.2 1.1 9.5 2.2 1.7 1 0 0 1 1 1 0 KIAA1045 RING finger Sulfate_transp PF00916.20 AIN99813.1 - 1.1e-45 156.0 19.6 1.7e-45 155.5 19.6 1.3 1 0 0 1 1 1 1 Sulfate permease family His_Phos_2 PF00328.22 AIN99813.1 - 5.9e-15 55.5 0.0 4.7e-14 52.5 0.0 2.1 2 0 0 2 2 2 1 Histidine phosphatase superfamily (branch 2) STAS PF01740.21 AIN99813.1 - 6.5e-08 32.2 0.0 1.3e-07 31.2 0.0 1.5 1 0 0 1 1 1 1 STAS domain zf-HIT PF04438.16 AIN99814.1 - 0.063 13.2 5.9 0.13 12.1 5.9 1.5 1 0 0 1 1 1 0 HIT zinc finger zf-B_box PF00643.24 AIN99814.1 - 0.076 13.2 1.9 0.17 12.0 1.9 1.6 1 0 0 1 1 1 0 B-box zinc finger RPN2_C PF18004.1 AIN99817.1 - 1.1e-29 103.5 0.0 1.8e-29 102.7 0.0 1.3 1 0 0 1 1 1 1 26S proteasome regulatory subunit RPN2 C-terminal domain HEAT_2 PF13646.6 AIN99817.1 - 5.2e-15 55.6 5.2 3.1e-12 46.7 0.0 4.8 4 1 0 5 5 5 1 HEAT repeats PC_rep PF01851.22 AIN99817.1 - 9.8e-15 54.1 8.6 0.39 11.3 0.0 8.1 7 0 0 7 7 7 4 Proteasome/cyclosome repeat Cnd1 PF12717.7 AIN99817.1 - 0.0053 16.8 3.7 0.42 10.6 0.1 3.2 4 0 0 4 4 4 2 non-SMC mitotic condensation complex subunit 1 TPR_14 PF13428.6 AIN99817.1 - 0.063 14.1 0.5 68 4.7 0.0 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.6 AIN99817.1 - 0.12 12.6 5.8 1.4e+02 3.1 0.0 5.4 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_2 PF07719.17 AIN99817.1 - 2.8 8.3 8.7 8.2 6.8 0.1 4.6 5 0 0 5 5 5 0 Tetratricopeptide repeat Methyltr_RsmB-F PF01189.17 AIN99818.1 - 2.8e-29 102.2 0.1 6.2e-16 58.6 0.1 2.3 2 0 0 2 2 2 2 16S rRNA methyltransferase RsmB/F ATP-grasp PF02222.22 AIN99818.1 - 0.095 12.3 0.1 0.58 9.7 0.0 2.4 3 0 0 3 3 3 0 ATP-grasp domain Methyltransf_30 PF05430.11 AIN99819.1 - 0.037 13.9 0.0 0.076 12.9 0.0 1.4 1 0 0 1 1 1 0 S-adenosyl-L-methionine-dependent methyltransferase Pkinase PF00069.25 AIN99820.1 - 1.5e-13 50.8 0.0 1.4e-12 47.6 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 AIN99820.1 - 0.00058 19.2 0.0 0.001 18.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase WD40 PF00400.32 AIN99820.1 - 0.0041 17.9 5.7 5.2 8.1 0.1 4.4 4 0 0 4 4 4 2 WD domain, G-beta repeat APH PF01636.23 AIN99820.1 - 0.032 14.2 0.2 0.032 14.2 0.2 2.8 2 1 1 3 3 3 0 Phosphotransferase enzyme family RIO1 PF01163.22 AIN99820.1 - 0.23 11.0 0.0 0.83 9.2 0.0 1.7 2 0 0 2 2 2 0 RIO1 family Sporozoite_P67 PF05642.11 AIN99820.1 - 5.5 5.0 8.2 15 3.5 8.2 1.7 1 0 0 1 1 1 0 Sporozoite P67 surface antigen ArfGap PF01412.18 AIN99821.1 - 1.4e-11 44.5 0.0 2.1e-11 43.9 0.0 1.3 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf Topoisom_bac PF01131.20 AIN99822.1 - 3e-108 362.5 0.0 3.8e-108 362.1 0.0 1.1 1 0 0 1 1 1 1 DNA topoisomerase Toprim PF01751.22 AIN99822.1 - 2.2e-18 66.4 0.0 3.9e-18 65.6 0.0 1.4 1 0 0 1 1 1 1 Toprim domain AAA PF00004.29 AIN99823.1 - 4.3e-31 108.1 0.0 6.4e-31 107.5 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 AIN99823.1 - 8.6e-06 26.2 0.0 1.9e-05 25.1 0.0 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_33 PF13671.6 AIN99823.1 - 1.7e-05 25.0 0.0 4.1e-05 23.8 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.6 AIN99823.1 - 3e-05 24.6 0.0 5.8e-05 23.6 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.6 AIN99823.1 - 3.3e-05 24.2 0.0 8e-05 22.9 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.14 AIN99823.1 - 0.00088 19.3 0.0 0.0015 18.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Cytidylate_kin PF02224.18 AIN99823.1 - 0.00094 19.0 0.0 0.0022 17.8 0.0 1.5 1 1 0 1 1 1 1 Cytidylate kinase AAA_28 PF13521.6 AIN99823.1 - 0.0015 18.8 0.0 0.0027 18.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 AIN99823.1 - 0.0016 18.8 0.0 0.0036 17.7 0.0 1.6 1 0 0 1 1 1 1 RNA helicase RuvB_N PF05496.12 AIN99823.1 - 0.0028 17.4 0.0 0.0097 15.7 0.0 1.8 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain TsaE PF02367.17 AIN99823.1 - 0.0044 17.0 0.0 0.0078 16.2 0.0 1.3 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_11 PF13086.6 AIN99823.1 - 0.007 16.2 0.0 0.011 15.5 0.0 1.3 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 AIN99823.1 - 0.012 15.3 0.0 0.031 14.0 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_7 PF12775.7 AIN99823.1 - 0.017 14.6 0.0 0.031 13.8 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_30 PF13604.6 AIN99823.1 - 0.023 14.4 0.0 0.075 12.7 0.0 1.8 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 AIN99823.1 - 0.037 13.9 0.0 0.077 12.9 0.0 1.5 1 0 0 1 1 1 0 NACHT domain AAA_25 PF13481.6 AIN99823.1 - 0.039 13.5 0.2 0.63 9.6 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.6 AIN99823.1 - 0.083 13.3 0.0 0.18 12.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain Rad17 PF03215.15 AIN99823.1 - 0.085 12.8 0.0 0.2 11.5 0.0 1.6 1 0 0 1 1 1 0 Rad17 P-loop domain Mg_chelatase PF01078.21 AIN99823.1 - 0.11 11.9 0.0 0.32 10.4 0.0 1.7 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI TIP49 PF06068.13 AIN99823.1 - 0.12 11.5 0.0 0.19 10.9 0.0 1.2 1 0 0 1 1 1 0 TIP49 P-loop domain KTI12 PF08433.10 AIN99823.1 - 0.15 11.5 0.0 0.23 10.8 0.0 1.4 1 0 0 1 1 1 0 Chromatin associated protein KTI12 PduV-EutP PF10662.9 AIN99823.1 - 0.15 11.8 0.1 0.5 10.1 0.0 1.9 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_2 PF07724.14 AIN99823.1 - 0.25 11.4 0.0 1.3 9.1 0.0 2.0 1 1 0 1 1 1 0 AAA domain (Cdc48 subfamily) Rep_fac-A_C PF08646.10 AIN99826.1 - 6.5e-41 139.5 0.7 1.8e-39 134.8 0.1 2.8 3 0 0 3 3 3 1 Replication factor-A C terminal domain REPA_OB_2 PF16900.5 AIN99826.1 - 2.1e-22 78.8 2.0 1.6e-20 72.8 0.8 2.5 2 0 0 2 2 2 1 Replication protein A OB domain tRNA_anti-codon PF01336.25 AIN99826.1 - 2.3e-12 46.7 0.7 7.2e-09 35.5 0.0 2.9 3 1 0 3 3 3 2 OB-fold nucleic acid binding domain CDC24_OB3 PF17244.2 AIN99826.1 - 7e-07 29.2 0.0 3.2e-05 23.7 0.0 2.6 2 1 0 2 2 2 1 Cell division control protein 24, OB domain 3 tRNA_anti_2 PF13742.6 AIN99826.1 - 0.031 14.5 0.0 0.099 12.9 0.0 1.8 2 0 0 2 2 2 0 OB-fold nucleic acid binding domain DZR PF12773.7 AIN99826.1 - 0.041 13.9 1.5 0.074 13.1 1.5 1.3 1 0 0 1 1 1 0 Double zinc ribbon zinc-ribbons_6 PF07191.12 AIN99826.1 - 0.051 13.5 1.0 0.1 12.6 1.0 1.4 1 0 0 1 1 1 0 zinc-ribbons SHS2_Rpb7-N PF03876.17 AIN99826.1 - 0.075 13.4 0.0 0.18 12.2 0.0 1.6 1 0 0 1 1 1 0 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 zf_UBZ PF18439.1 AIN99826.1 - 0.098 12.3 2.5 2.9 7.6 0.3 2.3 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger OrfB_Zn_ribbon PF07282.11 AIN99826.1 - 0.63 10.0 2.9 1.3 9.0 2.9 1.5 1 0 0 1 1 1 0 Putative transposase DNA-binding domain SNF2_N PF00176.23 AIN99827.1 - 2.7e-57 194.1 0.0 6e-57 192.9 0.0 1.6 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 AIN99827.1 - 3.5e-11 43.4 0.0 7e-11 42.5 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-C3HC4_2 PF13923.6 AIN99827.1 - 5e-10 39.1 10.1 5e-10 39.1 10.1 1.9 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 AIN99827.1 - 9.6e-10 38.2 9.4 2.5e-09 36.9 9.4 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 AIN99827.1 - 6.3e-09 36.0 10.3 6.3e-09 36.0 10.3 2.5 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.25 AIN99827.1 - 2.5e-08 33.7 10.6 7.3e-08 32.2 10.6 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 AIN99827.1 - 4e-08 33.0 9.1 8.8e-08 31.9 9.1 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 AIN99827.1 - 7.7e-08 32.2 7.0 1.9e-07 31.0 7.0 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 AIN99827.1 - 1.2e-06 28.4 8.9 3e-06 27.1 8.9 1.8 1 0 0 1 1 1 1 zinc-RING finger domain ResIII PF04851.15 AIN99827.1 - 1.6e-05 25.0 0.0 7.1e-05 22.9 0.0 2.0 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit zf-C3HC4_4 PF15227.6 AIN99827.1 - 0.00025 21.1 9.2 0.00065 19.8 9.2 1.8 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.7 AIN99827.1 - 0.001 19.3 5.5 0.001 19.3 5.5 2.3 2 0 0 2 2 2 1 RING-H2 zinc finger domain DEAD PF00270.29 AIN99827.1 - 0.0041 16.9 0.0 0.13 12.0 0.0 2.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase zf-RING_11 PF17123.5 AIN99827.1 - 0.016 15.0 7.2 0.04 13.7 7.2 1.8 1 0 0 1 1 1 0 RING-like zinc finger zf-RING_6 PF14835.6 AIN99827.1 - 0.063 13.1 4.3 0.2 11.6 4.3 1.8 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-RING_4 PF14570.6 AIN99827.1 - 0.13 12.1 7.0 0.31 10.9 7.0 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING_10 PF16685.5 AIN99827.1 - 0.77 9.9 5.4 2.4 8.4 5.4 1.8 1 0 0 1 1 1 0 zinc RING finger of MSL2 zf-P11 PF03854.14 AIN99827.1 - 2.5 7.8 8.5 1 9.1 4.4 2.4 2 0 0 2 2 2 0 P-11 zinc finger zf-Nse PF11789.8 AIN99827.1 - 4.4 7.2 6.1 9.9 6.1 6.1 1.6 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Aldolase_II PF00596.21 AIN99828.1 - 8.5e-41 139.9 0.0 9.7e-41 139.7 0.0 1.0 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain Kinesin PF00225.23 AIN99829.1 - 1.2e-85 287.4 0.2 2e-85 286.7 0.2 1.3 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 AIN99829.1 - 8.5e-36 123.1 0.0 8.6e-29 100.4 0.0 2.8 2 0 0 2 2 2 2 Microtubule binding DUF4530 PF15039.6 AIN99829.1 - 0.0095 16.1 4.3 3 8.0 2.1 2.8 2 0 0 2 2 2 2 Domain of unknown function (DUF4530) bZIP_1 PF00170.21 AIN99829.1 - 0.099 12.8 2.9 3.2 7.9 0.3 2.6 2 0 0 2 2 2 0 bZIP transcription factor UvsW PF11637.8 AIN99829.1 - 0.1 12.7 0.1 0.35 11.0 0.1 1.9 1 0 0 1 1 1 0 ATP-dependant DNA helicase UvsW TLE_N PF03920.15 AIN99829.1 - 0.14 12.2 3.7 7 6.7 0.3 2.8 3 0 0 3 3 3 0 Groucho/TLE N-terminal Q-rich domain GAS PF13851.6 AIN99829.1 - 0.6 9.4 14.1 1.2 8.4 3.7 2.4 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding UPF0242 PF06785.11 AIN99829.1 - 2.7 8.0 19.5 0.14 12.3 4.7 2.5 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus DUF4586 PF15239.6 AIN99830.1 - 2.7e-38 132.9 3.3 4.5e-38 132.2 3.3 1.3 1 1 0 1 1 1 1 Domain of unknown function (DUF4586) Methyltransf_16 PF10294.9 AIN99831.1 - 1.1e-13 51.3 0.7 1.5e-11 44.4 0.2 3.3 2 1 0 2 2 2 1 Lysine methyltransferase FAM86 PF14904.6 AIN99831.1 - 0.053 13.6 0.0 0.13 12.3 0.0 1.6 1 0 0 1 1 1 0 Family of unknown function RIBIOP_C PF04950.12 AIN99832.1 - 4.2e-74 249.6 0.0 4.2e-74 249.6 0.0 1.9 2 0 0 2 2 2 1 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal AARP2CN PF08142.12 AIN99832.1 - 1.2e-21 76.5 0.0 4.3e-21 74.8 0.0 2.0 2 0 0 2 2 1 1 AARP2CN (NUC121) domain AAA_22 PF13401.6 AIN99832.1 - 9.6e-05 22.7 0.0 0.00035 20.9 0.0 2.0 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 AIN99832.1 - 0.00028 21.3 0.2 0.00092 19.6 0.0 1.9 2 0 0 2 2 1 1 AAA ATPase domain AAA PF00004.29 AIN99832.1 - 0.0015 19.0 0.0 0.0039 17.6 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 AIN99832.1 - 0.0021 17.8 0.0 0.0044 16.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.23 AIN99832.1 - 0.0023 18.0 0.1 0.0085 16.2 0.1 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 AIN99832.1 - 0.0029 17.2 0.0 0.084 12.4 0.0 2.5 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain ABC_tran PF00005.27 AIN99832.1 - 0.012 16.2 0.1 0.053 14.0 0.0 2.1 2 0 0 2 2 1 0 ABC transporter AAA_5 PF07728.14 AIN99832.1 - 0.012 15.6 0.0 0.053 13.5 0.0 2.0 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) cobW PF02492.19 AIN99832.1 - 0.014 15.0 0.0 0.23 11.0 0.0 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.6 AIN99832.1 - 0.016 15.4 1.1 0.044 13.9 0.0 2.3 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.15 AIN99832.1 - 0.017 15.0 0.1 0.035 14.0 0.1 1.5 1 0 0 1 1 1 0 NTPase AAA_18 PF13238.6 AIN99832.1 - 0.031 14.8 0.2 0.26 11.8 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.6 AIN99832.1 - 0.033 14.5 0.5 0.083 13.2 0.0 1.8 2 0 0 2 2 1 0 AAA domain ATP_bind_1 PF03029.17 AIN99832.1 - 0.038 13.8 0.0 0.038 13.8 0.0 1.7 2 0 0 2 2 1 0 Conserved hypothetical ATP binding protein NACHT PF05729.12 AIN99832.1 - 0.048 13.6 0.0 0.11 12.4 0.0 1.6 1 0 0 1 1 1 0 NACHT domain NB-ARC PF00931.22 AIN99832.1 - 0.055 12.7 0.0 0.1 11.8 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain AAA_24 PF13479.6 AIN99832.1 - 0.082 12.6 0.6 0.31 10.7 0.0 2.2 3 0 0 3 3 2 0 AAA domain AAA_23 PF13476.6 AIN99832.1 - 0.1 13.1 6.8 22 5.5 1.0 3.4 3 0 0 3 3 3 0 AAA domain AAA_7 PF12775.7 AIN99832.1 - 0.11 12.1 0.0 0.19 11.2 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_17 PF13207.6 AIN99832.1 - 0.18 12.2 2.3 1.5 9.3 0.0 3.1 3 0 0 3 3 3 0 AAA domain DHHC PF01529.20 AIN99833.1 - 1.8e-22 79.9 12.8 1.8e-22 79.9 12.8 2.1 2 0 0 2 2 2 1 DHHC palmitoyltransferase IncD PF17628.2 AIN99833.1 - 0.048 13.4 2.4 0.088 12.6 2.4 1.3 1 0 0 1 1 1 0 Inclusion membrane protein D DnaJ PF00226.31 AIN99834.1 - 2e-07 31.0 0.0 3.8e-07 30.1 0.0 1.3 1 0 0 1 1 1 1 DnaJ domain RHINO PF15319.6 AIN99834.1 - 0.092 12.8 0.1 0.092 12.8 0.1 2.1 2 0 0 2 2 2 0 RAD9, RAD1, HUS1-interacting nuclear orphan protein BCIP PF13862.6 AIN99835.1 - 1.4e-31 109.9 0.0 2.1e-31 109.3 0.0 1.3 1 0 0 1 1 1 1 p21-C-terminal region-binding protein dsDNA_bind PF01984.20 AIN99836.1 - 6.6e-19 68.2 10.7 8.3e-19 67.9 10.7 1.0 1 0 0 1 1 1 1 Double-stranded DNA-binding domain DUF4748 PF15932.5 AIN99836.1 - 0.11 12.3 0.6 0.11 12.3 0.6 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4748) ATP-synt_G PF04718.15 AIN99836.1 - 1.3 9.9 4.6 11 7.0 1.6 2.0 1 1 1 2 2 2 0 Mitochondrial ATP synthase g subunit DUF2870 PF11069.8 AIN99836.1 - 3 8.3 7.6 1.6 9.2 4.8 1.9 1 1 0 2 2 2 0 Protein of unknown function (DUF2870) Zip PF02535.22 AIN99837.1 - 3.2e-44 151.5 9.2 3.2e-44 151.5 9.2 1.3 2 0 0 2 2 2 1 ZIP Zinc transporter FliC_SP PF12613.8 AIN99837.1 - 1.2 9.7 4.8 4.5 7.9 0.0 2.6 2 0 0 2 2 2 0 Flagellin structural protein CorA PF01544.18 AIN99838.1 - 1e-08 34.9 2.6 2.9e-08 33.4 1.9 1.8 2 0 0 2 2 2 1 CorA-like Mg2+ transporter protein MAPEG PF01124.18 AIN99838.1 - 0.044 13.7 0.0 0.35 10.8 0.0 2.3 2 0 0 2 2 2 0 MAPEG family Peptidase_S15 PF02129.18 AIN99839.1 - 3.2e-58 197.5 0.3 1.9e-57 194.9 0.1 2.2 3 0 0 3 3 3 1 X-Pro dipeptidyl-peptidase (S15 family) PepX_C PF08530.10 AIN99839.1 - 1.2e-32 113.7 0.0 1.9e-32 113.1 0.0 1.2 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain Hydrolase_4 PF12146.8 AIN99839.1 - 4.7e-09 35.9 0.1 2.5e-07 30.2 0.1 2.2 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 AIN99839.1 - 1.9e-07 31.0 0.0 3.2e-07 30.3 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 AIN99839.1 - 1.4e-06 27.9 0.4 2.4e-05 23.9 0.1 2.3 2 0 0 2 2 2 1 Prolyl oligopeptidase family AXE1 PF05448.12 AIN99839.1 - 0.0022 16.7 0.0 0.0068 15.1 0.0 1.7 1 1 1 2 2 2 1 Acetyl xylan esterase (AXE1) DLH PF01738.18 AIN99839.1 - 0.12 11.9 0.0 0.3 10.6 0.0 1.6 2 0 0 2 2 2 0 Dienelactone hydrolase family GTP_EFTU PF00009.27 AIN99840.1 - 1.3e-41 142.2 0.0 2.4e-41 141.4 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_II PF14492.6 AIN99840.1 - 3e-19 68.9 0.0 5.7e-19 68.0 0.0 1.5 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_C PF00679.24 AIN99840.1 - 3e-13 49.6 0.0 6.4e-13 48.6 0.0 1.5 1 0 0 1 1 1 1 Elongation factor G C-terminus RF3_C PF16658.5 AIN99840.1 - 7.4e-07 29.1 0.0 1.5e-06 28.0 0.0 1.4 1 0 0 1 1 1 1 Class II release factor RF3, C-terminal domain GTP_EFTU_D2 PF03144.25 AIN99840.1 - 1.2e-06 28.8 0.0 3.5e-06 27.3 0.0 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 AIN99840.1 - 0.00083 19.4 0.0 0.002 18.2 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase AIG1 PF04548.16 AIN99840.1 - 0.012 15.0 0.0 0.022 14.1 0.0 1.3 1 0 0 1 1 1 0 AIG1 family SRPRB PF09439.10 AIN99840.1 - 0.031 13.7 0.0 0.059 12.8 0.0 1.4 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit FeoB_N PF02421.18 AIN99840.1 - 0.081 12.4 0.0 0.27 10.8 0.0 1.8 1 1 0 1 1 1 0 Ferrous iron transport protein B LacAB_rpiB PF02502.18 AIN99841.1 - 1.6e-51 174.0 0.7 1.8e-51 173.8 0.7 1.0 1 0 0 1 1 1 1 Ribose/Galactose Isomerase LRR_6 PF13516.6 AIN99843.1 - 3.4e-17 60.9 6.6 0.031 14.3 0.0 7.0 6 0 0 6 6 6 5 Leucine Rich repeat LRR_4 PF12799.7 AIN99843.1 - 9.8e-10 38.5 7.8 0.015 15.7 0.1 5.0 4 1 1 5 5 5 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 AIN99843.1 - 0.00068 19.4 13.4 0.098 12.4 0.8 5.2 4 2 0 4 4 4 2 Leucine rich repeat PspA_IM30 PF04012.12 AIN99843.1 - 0.012 15.2 0.6 0.056 13.0 0.6 2.2 1 0 0 1 1 1 0 PspA/IM30 family LRR_1 PF00560.33 AIN99843.1 - 0.013 16.0 4.4 89 4.3 0.0 5.6 4 2 0 4 4 4 0 Leucine Rich Repeat DivIC PF04977.15 AIN99843.1 - 0.061 13.1 2.0 0.2 11.5 2.0 1.8 1 0 0 1 1 1 0 Septum formation initiator SlyX PF04102.12 AIN99843.1 - 0.064 13.9 0.7 0.22 12.1 0.7 2.0 1 0 0 1 1 1 0 SlyX Spectrin PF00435.21 AIN99843.1 - 0.07 13.6 0.5 0.18 12.3 0.5 1.6 1 0 0 1 1 1 0 Spectrin repeat DUF4407 PF14362.6 AIN99843.1 - 0.24 10.7 3.0 0.52 9.6 3.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Anophelin PF10731.9 AIN99844.1 - 5.7 6.9 5.9 1.2 9.0 2.7 1.6 2 0 0 2 2 2 0 Thrombin inhibitor from mosquito Pkinase PF00069.25 AIN99845.1 - 3.9e-47 160.8 0.0 8.6e-47 159.7 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 AIN99845.1 - 1.5e-21 76.9 0.0 2.2e-21 76.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 AIN99845.1 - 6.8e-05 21.8 0.0 0.00015 20.7 0.0 1.5 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 AIN99845.1 - 0.02 14.2 0.0 0.032 13.5 0.0 1.3 1 0 0 1 1 1 0 Kinase-like APH PF01636.23 AIN99845.1 - 0.037 14.0 0.0 0.074 13.0 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Choline_kinase PF01633.20 AIN99845.1 - 0.04 13.5 0.0 0.071 12.7 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase Kdo PF06293.14 AIN99845.1 - 0.062 12.6 0.0 0.12 11.7 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Sporozoite_P67 PF05642.11 AIN99845.1 - 0.24 9.4 4.4 0.45 8.5 4.4 1.4 1 0 0 1 1 1 0 Sporozoite P67 surface antigen D123 PF07065.14 AIN99846.1 - 0.023 13.9 0.0 0.075 12.2 0.0 1.8 2 1 0 2 2 2 0 D123 zf-dskA_traR PF01258.17 AIN99846.1 - 0.081 12.9 0.0 0.21 11.6 0.0 1.7 1 0 0 1 1 1 0 Prokaryotic dksA/traR C4-type zinc finger DUF2783 PF10932.8 AIN99847.1 - 0.1 12.3 0.0 0.29 10.8 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2783) Spc7 PF08317.11 AIN99847.1 - 7 5.4 47.6 24 3.6 17.9 2.8 1 1 1 2 2 2 0 Spc7 kinetochore protein GRIM-19 PF06212.12 AIN99848.1 - 7.2e-09 35.7 0.1 1e-08 35.2 0.1 1.2 1 0 0 1 1 1 1 GRIM-19 protein DPCD PF14913.6 AIN99849.1 - 1.8e-66 223.2 0.0 2e-66 223.0 0.0 1.0 1 0 0 1 1 1 1 DPCD protein family TilS_C PF11734.8 AIN99849.1 - 0.13 11.7 0.0 0.26 10.7 0.0 1.4 1 0 0 1 1 1 0 TilS substrate C-terminal domain AMP-binding PF00501.28 AIN99850.1 - 1.4e-27 96.4 0.0 3.5e-27 95.1 0.0 1.7 1 0 0 1 1 1 1 AMP-binding enzyme Ank_4 PF13637.6 AIN99850.1 - 1.9e-14 53.8 0.1 2.9e-09 37.3 0.0 3.0 2 1 0 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 AIN99850.1 - 2.5e-13 50.4 0.2 1.2e-06 29.0 0.0 2.7 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 AIN99850.1 - 6.4e-09 35.9 4.2 0.00016 21.9 0.1 4.5 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 AIN99850.1 - 6.5e-09 35.3 1.5 0.033 14.7 0.0 5.7 6 0 0 6 6 6 2 Ankyrin repeat Ank PF00023.30 AIN99850.1 - 9.8e-06 25.8 10.5 0.021 15.3 0.0 5.5 6 0 0 6 6 6 1 Ankyrin repeat PP-binding PF00550.25 AIN99850.1 - 0.016 15.6 0.0 0.039 14.3 0.0 1.7 1 0 0 1 1 1 0 Phosphopantetheine attachment site RNA_pol_L_2 PF13656.6 AIN99851.1 - 3.6e-23 81.1 0.0 5.4e-23 80.6 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.24 AIN99851.1 - 7e-05 22.2 0.0 0.00014 21.2 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Sua5_yciO_yrdC PF01300.18 AIN99852.1 - 3.8e-47 160.1 0.0 5.3e-47 159.6 0.0 1.2 1 0 0 1 1 1 1 Telomere recombination SUA5 PF03481.13 AIN99852.1 - 1.4e-12 48.3 0.0 2.7e-12 47.4 0.0 1.5 1 0 0 1 1 1 1 Putative GTP-binding controlling metal-binding Helicase_C PF00271.31 AIN99853.1 - 3.3e-27 95.0 0.1 3.3e-27 95.0 0.1 1.9 2 1 1 3 3 3 1 Helicase conserved C-terminal domain ERCC3_RAD25_C PF16203.5 AIN99853.1 - 8.1e-05 21.9 0.0 0.00013 21.3 0.0 1.3 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase CEP76-C2 PF15627.6 AIN99854.1 - 1.3e-37 128.8 0.0 2.2e-37 128.0 0.0 1.3 1 0 0 1 1 1 1 CEP76 C2 domain Transglut_core PF01841.19 AIN99854.1 - 0.15 12.6 0.0 0.59 10.6 0.0 2.1 2 0 0 2 2 2 0 Transglutaminase-like superfamily UPF0220 PF05255.11 AIN99855.1 - 2.7e-15 56.3 2.1 3e-15 56.1 2.1 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0220) LptF_LptG PF03739.14 AIN99855.1 - 0.41 9.4 10.9 0.21 10.4 2.7 2.0 2 0 0 2 2 2 0 Lipopolysaccharide export system permease LptF/LptG GDPD PF03009.17 AIN99856.1 - 1.4e-18 67.6 0.0 1.1e-15 58.2 0.0 2.2 2 0 0 2 2 2 2 Glycerophosphoryl diester phosphodiesterase family PI-PLC-X PF00388.19 AIN99856.1 - 0.05 13.2 0.0 0.18 11.4 0.0 1.7 2 0 0 2 2 2 0 Phosphatidylinositol-specific phospholipase C, X domain Cullin PF00888.22 AIN99857.1 - 1.4e-37 129.7 0.7 2.2e-37 129.0 0.7 1.3 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 AIN99857.1 - 1.9e-09 37.4 0.0 1.3e-08 34.7 0.0 2.5 2 0 0 2 2 2 1 Cullin protein neddylation domain TrmB PF01978.19 AIN99857.1 - 0.013 15.4 1.5 0.11 12.5 0.1 2.6 2 0 0 2 2 2 0 Sugar-specific transcriptional regulator TrmB Penicillinase_R PF03965.16 AIN99857.1 - 0.023 15.0 0.1 0.15 12.4 0.0 2.5 2 0 0 2 2 2 0 Penicillinase repressor Cullin PF00888.22 AIN99858.1 - 7.3e-38 130.6 0.0 1.6e-37 129.4 0.0 1.5 1 1 0 1 1 1 1 Cullin family Penicillinase_R PF03965.16 AIN99858.1 - 0.00034 21.0 0.0 0.0015 18.9 0.0 2.2 1 0 0 1 1 1 1 Penicillinase repressor HTH_20 PF12840.7 AIN99858.1 - 0.0076 16.3 0.4 4.9 7.3 0.1 3.3 4 0 0 4 4 4 2 Helix-turn-helix domain Cullin_Nedd8 PF10557.9 AIN99858.1 - 0.0087 16.1 0.0 0.025 14.6 0.0 1.8 1 0 0 1 1 1 1 Cullin protein neddylation domain ANAPC2 PF08672.11 AIN99858.1 - 0.099 13.2 0.2 2.3 8.8 0.0 2.7 2 0 0 2 2 2 0 Anaphase promoting complex (APC) subunit 2 Dynein_light PF01221.18 AIN99859.1 - 1e-31 109.1 0.0 1.1e-31 109.0 0.0 1.0 1 0 0 1 1 1 1 Dynein light chain type 1 TINF2_N PF14973.6 AIN99859.1 - 0.18 12.2 0.0 0.2 12.0 0.0 1.1 1 0 0 1 1 1 0 TERF1-interacting nuclear factor 2 N-terminus HhH-GPD PF00730.25 AIN99860.1 - 1e-16 61.3 0.0 5.4e-16 59.0 0.0 2.2 2 0 0 2 2 2 1 HhH-GPD superfamily base excision DNA repair protein NUDIX_4 PF14815.6 AIN99860.1 - 7.2e-13 48.5 0.0 1.8e-12 47.2 0.0 1.7 1 1 0 1 1 1 1 NUDIX domain HHH PF00633.23 AIN99860.1 - 1.6e-05 24.5 0.1 4.8e-05 23.0 0.0 1.9 2 0 0 2 2 2 1 Helix-hairpin-helix motif HHH_5 PF14520.6 AIN99860.1 - 0.16 12.6 0.0 1 10.0 0.0 2.3 3 0 0 3 3 3 0 Helix-hairpin-helix domain HHH_2 PF12826.7 AIN99860.1 - 0.19 11.8 0.0 9.6 6.4 0.0 2.4 2 0 0 2 2 2 0 Helix-hairpin-helix motif Kelch_4 PF13418.6 AIN99861.1 - 7.4e-08 32.3 0.0 5.5e-05 23.1 0.0 3.5 2 0 0 2 2 2 1 Galactose oxidase, central domain Kelch_6 PF13964.6 AIN99861.1 - 1e-07 31.9 0.1 0.0008 19.6 0.0 3.9 3 0 0 3 3 3 2 Kelch motif Kelch_3 PF13415.6 AIN99861.1 - 1.7e-07 31.3 0.1 0.02 15.2 0.0 3.8 3 0 0 3 3 3 2 Galactose oxidase, central domain Kelch_5 PF13854.6 AIN99861.1 - 4.4e-06 26.6 0.5 0.00016 21.6 0.0 3.4 3 0 0 3 3 3 1 Kelch motif Kelch_2 PF07646.15 AIN99861.1 - 0.00027 20.8 0.0 0.00027 20.8 0.0 3.4 4 0 0 4 4 4 1 Kelch motif APS-reductase_C PF12139.8 AIN99861.1 - 0.00036 20.7 0.0 0.00082 19.5 0.0 1.5 1 0 0 1 1 1 1 Adenosine-5'-phosphosulfate reductase beta subunit Kelch_1 PF01344.25 AIN99861.1 - 0.0017 17.9 0.1 0.45 10.1 0.0 3.0 2 0 0 2 2 2 1 Kelch motif Methyltransf_25 PF13649.6 AIN99862.1 - 1e-07 32.6 0.0 2.6e-07 31.2 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 AIN99862.1 - 4.4e-05 24.0 0.0 0.00015 22.4 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 AIN99862.1 - 0.00017 22.2 0.0 0.00029 21.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 AIN99862.1 - 0.018 14.9 0.0 0.025 14.4 0.0 1.3 1 1 0 1 1 1 0 Methyltransferase domain UPF0020 PF01170.18 AIN99862.1 - 0.11 12.2 0.0 0.16 11.7 0.0 1.3 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 YgbA_NO PF11756.8 AIN99862.1 - 0.12 12.8 0.0 0.19 12.1 0.0 1.3 1 0 0 1 1 1 0 Nitrous oxide-stimulated promoter CorA PF01544.18 AIN99863.1 - 0.23 10.7 1.7 0.4 9.9 1.7 1.3 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein ROS_MUCR PF05443.11 AIN99863.1 - 0.45 10.6 2.4 0.35 10.9 0.2 2.1 2 0 0 2 2 2 0 ROS/MUCR transcriptional regulator protein Sel1 PF08238.12 AIN99863.1 - 0.52 11.1 7.6 0.58 10.9 0.1 3.6 4 0 0 4 4 4 0 Sel1 repeat CortBP2 PF09727.9 AIN99865.1 - 0.037 13.9 15.6 0.79 9.6 1.6 2.3 2 0 0 2 2 2 0 Cortactin-binding protein-2 Jnk-SapK_ap_N PF09744.9 AIN99865.1 - 0.054 13.7 14.8 0.82 9.9 0.5 2.4 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 SAP30_Sin3_bdg PF13867.6 AIN99865.1 - 0.13 12.6 0.6 0.31 11.4 0.6 1.5 1 0 0 1 1 1 0 Sin3 binding region of histone deacetylase complex subunit SAP30 Exonuc_VII_L PF02601.15 AIN99865.1 - 5.6 6.4 10.1 6 6.4 4.2 2.5 2 0 0 2 2 2 0 Exonuclease VII, large subunit Glyco_hydro_63 PF03200.16 AIN99866.1 - 4.5e-47 160.9 1.6 2.5e-44 151.9 1.6 2.2 1 1 0 1 1 1 1 Glycosyl hydrolase family 63 C-terminal domain Glyco_hydro_63N PF16923.5 AIN99866.1 - 4.8e-16 59.6 0.2 1.4e-15 58.0 0.2 1.7 1 1 0 1 1 1 1 Glycosyl hydrolase family 63 N-terminal domain CsiV PF10972.8 AIN99866.1 - 0.083 12.6 0.0 0.14 11.9 0.0 1.3 1 0 0 1 1 1 0 Peptidoglycan-binding protein, CsiV Ribosomal_S14 PF00253.21 AIN99867.1 - 2.5e-11 43.1 3.5 2.7e-11 43.0 3.5 1.1 1 0 0 1 1 1 1 Ribosomal protein S14p/S29e PhosphMutase PF10143.9 AIN99869.1 - 2.3e-43 148.0 0.0 5.4e-43 146.8 0.0 1.7 1 0 0 1 1 1 1 2,3-bisphosphoglycerate-independent phosphoglycerate mutase Metalloenzyme PF01676.18 AIN99869.1 - 4.2e-15 55.8 0.0 1.7e-14 53.8 0.0 1.9 1 1 0 1 1 1 1 Metalloenzyme superfamily GGACT PF06094.12 AIN99869.1 - 7.4e-10 39.5 0.0 2.1e-09 38.0 0.0 1.8 1 0 0 1 1 1 1 Gamma-glutamyl cyclotransferase, AIG2-like XdhC_CoxI PF02625.16 AIN99869.1 - 0.017 15.3 0.6 12 6.1 0.1 3.2 2 0 0 2 2 2 0 XdhC and CoxI family Cyclin_N PF00134.23 AIN99870.1 - 0.00045 20.0 0.1 0.00091 19.0 0.1 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain BCL9 PF11502.8 AIN99870.1 - 1 9.2 3.9 2.7 7.8 3.9 1.7 1 0 0 1 1 1 0 B-cell lymphoma 9 protein PEX11 PF05648.14 AIN99872.1 - 0.0012 18.3 0.8 0.0017 17.9 0.8 1.3 1 1 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) PEX11 PF05648.14 AIN99873.1 - 9e-22 77.6 1.0 1.6e-21 76.8 1.0 1.4 1 1 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) MOZ_SAS PF01853.18 AIN99874.1 - 7.9e-41 139.7 0.2 9.6e-22 77.5 0.4 3.1 3 0 0 3 3 3 3 MOZ/SAS family DNA_topoisoIV PF00521.20 AIN99875.1 - 1.5e-129 432.6 0.0 2.7e-129 431.8 0.0 1.4 1 0 0 1 1 1 1 DNA gyrase/topoisomerase IV, subunit A TOPRIM_C PF16898.5 AIN99875.1 - 1.5e-42 144.9 0.1 3.8e-42 143.6 0.1 1.8 1 0 0 1 1 1 1 C-terminal associated domain of TOPRIM DNA_gyraseB PF00204.25 AIN99875.1 - 3.7e-20 72.1 0.1 8.4e-20 71.0 0.1 1.5 1 0 0 1 1 1 1 DNA gyrase B HATPase_c PF02518.26 AIN99875.1 - 9e-09 35.8 0.0 2.6e-08 34.4 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Toprim PF01751.22 AIN99875.1 - 0.00039 20.6 0.0 0.001 19.3 0.0 1.7 1 0 0 1 1 1 1 Toprim domain DNA_gyraseB_C PF00986.21 AIN99875.1 - 0.0093 16.1 0.0 0.029 14.5 0.0 1.9 1 0 0 1 1 1 1 DNA gyrase B subunit, carboxyl terminus PBP1_TM PF14812.6 AIN99875.1 - 0.65 10.4 17.6 0.031 14.6 3.4 4.1 4 0 0 4 4 4 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Hexapep PF00132.24 AIN99876.1 - 4.4e-07 29.4 1.4 0.2 11.4 0.2 4.0 1 1 3 4 4 4 4 Bacterial transferase hexapeptide (six repeats) NTP_transferase PF00483.23 AIN99876.1 - 0.0099 15.5 0.0 0.066 12.8 0.0 2.0 2 0 0 2 2 2 1 Nucleotidyl transferase NTP_transf_3 PF12804.7 AIN99876.1 - 0.015 15.7 0.2 0.042 14.2 0.2 1.8 1 1 0 1 1 1 0 MobA-like NTP transferase domain DUF4954 PF16314.5 AIN99876.1 - 0.023 12.9 0.1 0.033 12.3 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4954) Fucokinase PF07959.12 AIN99876.1 - 0.071 12.0 0.1 0.14 11.0 0.1 1.4 1 0 0 1 1 1 0 L-fucokinase Hexapep_2 PF14602.6 AIN99876.1 - 0.39 10.5 4.2 3.1 7.6 0.5 3.6 1 1 2 3 3 3 0 Hexapeptide repeat of succinyl-transferase Cep57_MT_bd PF06657.13 AIN99877.1 - 0.0014 19.0 0.1 0.0014 19.0 0.1 3.4 3 1 0 3 3 3 1 Centrosome microtubule-binding domain of Cep57 CENP-H PF05837.12 AIN99877.1 - 0.087 13.2 0.1 0.087 13.2 0.1 3.3 2 1 1 3 3 3 0 Centromere protein H (CENP-H) OmpH PF03938.14 AIN99877.1 - 0.12 12.7 6.0 7.6 6.9 0.0 2.4 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) UPF0184 PF03670.13 AIN99877.1 - 0.52 10.7 6.4 0.52 10.7 1.8 2.5 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0184) PCI PF01399.27 AIN99878.1 - 6.5e-11 42.7 1.0 1.5e-10 41.5 1.0 1.7 1 0 0 1 1 1 1 PCI domain eIF3_N PF09440.10 AIN99878.1 - 9.8e-10 39.0 3.5 1.1e-09 38.8 1.6 2.1 2 1 0 2 2 2 1 eIF3 subunit 6 N terminal domain SUIM_assoc PF16619.5 AIN99879.1 - 0.054 13.6 1.4 0.23 11.5 0.1 2.8 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 CactinC_cactus PF09732.9 AIN99880.1 - 1.9e-37 128.0 1.5 3.2e-37 127.2 1.5 1.4 1 0 0 1 1 1 1 Cactus-binding C-terminus of cactin protein Herpes_capsid PF06112.11 AIN99881.1 - 0.71 9.9 5.6 1.1 9.3 5.6 1.3 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein SHMT PF00464.19 AIN99883.1 - 2.1e-178 593.0 0.0 2.7e-178 592.6 0.0 1.1 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Aminotran_5 PF00266.19 AIN99883.1 - 0.0044 16.0 0.0 0.0079 15.2 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 AIN99883.1 - 0.007 15.7 0.1 0.027 13.8 0.1 2.1 1 1 0 1 1 1 1 Beta-eliminating lyase Sterol-sensing PF12349.8 AIN99884.1 - 0.002 18.0 7.8 0.002 18.0 7.8 3.3 4 0 0 4 4 4 1 Sterol-sensing domain of SREBP cleavage-activation Lectin_N PF03954.14 AIN99884.1 - 0.16 11.7 0.3 8.3 6.2 0.0 2.6 2 0 0 2 2 2 0 Hepatic lectin, N-terminal domain MCM PF00493.23 AIN99885.1 - 1.8e-91 305.2 0.2 2.7e-91 304.6 0.2 1.3 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 AIN99885.1 - 7.9e-35 119.5 0.6 1.4e-34 118.6 0.6 1.4 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 AIN99885.1 - 7.9e-22 77.5 4.8 1.3e-21 76.8 3.5 2.1 3 0 0 3 3 3 1 MCM AAA-lid domain MCM6_C PF18263.1 AIN99885.1 - 3.7e-09 36.8 0.0 7.8e-09 35.7 0.0 1.5 1 0 0 1 1 1 1 MCM6 C-terminal winged-helix domain Mg_chelatase PF01078.21 AIN99885.1 - 5.6e-07 29.1 0.0 3.8e-06 26.4 0.0 2.2 1 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 AIN99885.1 - 0.00067 19.7 0.2 0.003 17.5 0.0 2.1 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) MCM_N PF14551.6 AIN99885.1 - 0.00094 19.7 0.0 0.0026 18.3 0.0 1.8 1 0 0 1 1 1 1 MCM N-terminal domain AAA_3 PF07726.11 AIN99885.1 - 0.0061 16.4 0.0 0.016 15.0 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 AIN99885.1 - 0.0086 15.8 0.0 0.021 14.6 0.0 1.6 1 0 0 1 1 1 1 Sigma-54 interaction domain DUF188 PF02639.14 AIN99885.1 - 0.21 11.2 0.9 13 5.4 0.1 2.5 2 0 0 2 2 2 0 Uncharacterized BCR, YaiI/YqxD family COG1671 Mg_chelatase_C PF13335.6 AIN99885.1 - 0.98 10.1 4.6 28 5.4 0.6 2.8 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI C-terminal WW PF00397.26 AIN99886.1 - 3.4e-09 36.6 0.9 7.7e-09 35.5 0.9 1.7 1 0 0 1 1 1 1 WW domain GCD14 PF08704.10 AIN99887.1 - 3.6e-64 216.8 0.5 4.7e-38 131.3 0.0 3.0 1 1 2 3 3 3 2 tRNA methyltransferase complex GCD14 subunit Methyltransf_31 PF13847.6 AIN99887.1 - 3.9e-09 36.5 0.0 9.2e-09 35.3 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 AIN99887.1 - 7.6e-08 33.0 0.1 0.00037 21.1 0.0 2.5 1 1 1 2 2 2 2 Methyltransferase domain PCMT PF01135.19 AIN99887.1 - 2.1e-06 27.7 0.0 5.4e-06 26.3 0.0 1.7 1 1 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) GCD14_N PF14801.6 AIN99887.1 - 2.2e-05 24.2 0.3 5.4e-05 22.9 0.3 1.7 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit N-term Fibrillarin PF01269.17 AIN99887.1 - 0.00018 20.7 0.0 0.092 11.8 0.0 2.2 2 0 0 2 2 2 2 Fibrillarin Methyltransf_11 PF08241.12 AIN99887.1 - 0.00027 21.5 0.1 0.0008 20.0 0.1 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 AIN99887.1 - 0.0038 17.9 0.0 0.046 14.5 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_24 PF13578.6 AIN99887.1 - 0.0043 18.1 0.1 0.011 16.8 0.1 1.7 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 AIN99887.1 - 0.0045 16.3 0.0 0.04 13.3 0.0 2.0 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.14 AIN99887.1 - 0.0059 16.2 0.0 0.02 14.4 0.0 1.9 1 1 1 2 2 2 1 Methyltransferase small domain Methyltr_RsmB-F PF01189.17 AIN99887.1 - 0.019 14.6 0.1 0.082 12.5 0.1 2.1 1 1 0 1 1 1 0 16S rRNA methyltransferase RsmB/F RrnaAD PF00398.20 AIN99887.1 - 0.021 13.9 0.0 0.032 13.3 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase PrmA PF06325.13 AIN99887.1 - 0.026 13.9 0.0 0.047 13.1 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) CMAS PF02353.20 AIN99887.1 - 0.1 11.9 0.0 0.2 10.9 0.0 1.4 2 0 0 2 2 2 0 Mycolic acid cyclopropane synthetase Rft-1 PF04506.13 AIN99888.1 - 2.6e-45 155.1 12.3 7.7e-39 133.8 9.8 2.5 2 1 0 2 2 2 2 Rft protein 2-oxoacid_dh PF00198.23 AIN99889.1 - 4.9e-80 268.3 0.6 6.4e-80 267.9 0.6 1.1 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 AIN99889.1 - 8.7e-20 70.3 1.1 1.5e-19 69.6 1.1 1.4 1 0 0 1 1 1 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.6 AIN99889.1 - 5.3e-05 23.0 0.2 0.24 11.3 0.1 2.4 1 1 1 2 2 2 2 Biotin-lipoyl like GCV_H PF01597.19 AIN99889.1 - 0.0027 17.6 0.6 0.0053 16.6 0.6 1.5 1 0 0 1 1 1 1 Glycine cleavage H-protein HlyD_D23 PF16576.5 AIN99889.1 - 0.029 13.6 0.1 0.19 10.9 0.0 2.0 1 1 1 2 2 2 0 Barrel-sandwich domain of CusB or HlyD membrane-fusion HlyD_3 PF13437.6 AIN99889.1 - 0.045 14.5 0.5 1.5 9.6 0.0 2.5 1 1 1 2 2 2 0 HlyD family secretion protein ATP-synt_ab PF00006.25 AIN99890.1 - 5.6e-68 228.8 0.0 7.2e-68 228.4 0.0 1.1 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N PF02874.23 AIN99890.1 - 8.4e-14 51.9 0.7 1.7e-13 50.9 0.7 1.6 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain NTP_transferase PF00483.23 AIN99891.1 - 1.6e-05 24.6 0.0 8.9e-05 22.2 0.0 2.1 3 0 0 3 3 3 1 Nucleotidyl transferase Hexapep PF00132.24 AIN99891.1 - 0.0053 16.4 10.8 2.7 7.9 0.0 3.5 1 1 2 3 3 3 3 Bacterial transferase hexapeptide (six repeats) Fucokinase PF07959.12 AIN99891.1 - 0.0065 15.4 0.1 0.01 14.8 0.1 1.2 1 0 0 1 1 1 1 L-fucokinase NTP_transf_3 PF12804.7 AIN99891.1 - 0.014 15.8 0.0 0.16 12.4 0.0 2.5 1 1 0 1 1 1 0 MobA-like NTP transferase domain HTH_DeoR PF08220.12 AIN99891.1 - 0.14 11.9 0.0 0.45 10.3 0.0 1.9 1 0 0 1 1 1 0 DeoR-like helix-turn-helix domain DUF676 PF05057.14 AIN99892.1 - 3.4e-11 43.1 0.1 1.5e-10 40.9 0.1 1.9 1 1 0 1 1 1 1 Putative serine esterase (DUF676) Palm_thioest PF02089.15 AIN99892.1 - 0.0058 16.5 0.0 0.0094 15.8 0.0 1.3 1 0 0 1 1 1 1 Palmitoyl protein thioesterase Ribosomal_S14 PF00253.21 AIN99893.1 - 2.5e-11 43.1 3.5 2.7e-11 43.0 3.5 1.1 1 0 0 1 1 1 1 Ribosomal protein S14p/S29e ParA PF10609.9 AIN99894.1 - 6.7e-90 300.8 0.0 7.7e-90 300.6 0.0 1.0 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 AIN99894.1 - 6.3e-16 58.6 0.0 2.4e-15 56.7 0.0 1.8 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.6 AIN99894.1 - 1.6e-12 47.7 1.7 3e-10 40.3 0.2 2.1 2 0 0 2 2 2 2 AAA domain MipZ PF09140.11 AIN99894.1 - 4.2e-08 32.8 1.1 2.5e-07 30.3 1.1 1.9 1 1 0 1 1 1 1 ATPase MipZ VirC1 PF07015.11 AIN99894.1 - 3.6e-05 23.2 0.1 6.9e-05 22.3 0.1 1.4 1 0 0 1 1 1 1 VirC1 protein Fer4_NifH PF00142.18 AIN99894.1 - 0.00011 21.7 0.0 0.00067 19.2 0.1 1.9 2 0 0 2 2 2 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family ArsA_ATPase PF02374.15 AIN99894.1 - 0.00056 19.2 0.4 0.0021 17.3 0.4 1.8 2 0 0 2 2 2 1 Anion-transporting ATPase CBP_BcsQ PF06564.12 AIN99894.1 - 0.027 14.0 0.1 0.11 11.9 0.1 1.9 1 1 0 1 1 1 0 Cellulose biosynthesis protein BcsQ AAA_26 PF13500.6 AIN99894.1 - 0.094 12.5 0.2 14 5.4 0.1 2.3 2 0 0 2 2 2 0 AAA domain DUF1611 PF07755.11 AIN99894.1 - 0.11 11.8 1.2 0.21 10.8 0.3 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF1611_C) P-loop domain MeaB PF03308.16 AIN99894.1 - 0.16 10.9 0.4 0.25 10.3 0.4 1.2 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB TFIIE-A_C PF11521.8 AIN99896.1 - 1.8 8.9 13.2 0.34 11.2 2.4 2.9 3 0 0 3 3 3 0 C-terminal general transcription factor TFIIE alpha SDA1 PF05285.12 AIN99896.1 - 3.4 7.0 8.2 5.2 6.4 8.2 1.3 1 0 0 1 1 1 0 SDA1 IF4E PF01652.18 AIN99897.1 - 4.9e-30 104.4 0.0 6.5e-30 104.0 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E MRP-L20 PF12824.7 AIN99897.1 - 0.0062 16.7 0.4 0.012 15.7 0.4 1.4 1 0 0 1 1 1 1 Mitochondrial ribosomal protein subunit L20 PAM2 PF07145.15 AIN99897.1 - 0.013 15.1 0.6 2.6 7.9 0.0 2.8 2 0 0 2 2 2 0 Ataxin-2 C-terminal region Acyl-CoA_dh_C PF12806.7 AIN99898.1 - 4.2e-25 88.3 1.5 1e-24 87.1 1.5 1.6 1 0 0 1 1 1 1 Acetyl-CoA dehydrogenase C-terminal like Acyl-CoA_dh_1 PF00441.24 AIN99898.1 - 3.6e-19 69.5 4.0 5e-18 65.7 4.0 2.4 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 AIN99898.1 - 7.8e-19 67.7 0.0 1.6e-18 66.6 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 AIN99898.1 - 3.4e-11 43.8 0.1 7.1e-11 42.8 0.1 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 AIN99898.1 - 1.4e-05 25.3 0.2 3.4e-05 24.1 0.2 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain R3H PF01424.22 AIN99899.1 - 2.5e-10 40.2 0.3 5.6e-10 39.1 0.3 1.6 1 0 0 1 1 1 1 R3H domain PIF1 PF05970.14 AIN99900.1 - 4e-30 105.2 0.1 6.4e-25 88.1 0.0 3.9 4 0 0 4 4 4 2 PIF1-like helicase AAA_30 PF13604.6 AIN99900.1 - 6.6e-15 55.3 0.6 1.4e-14 54.2 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 AIN99900.1 - 5.3e-06 26.8 0.1 2.8e-05 24.5 0.1 2.3 1 1 0 1 1 1 1 AAA domain UvrD_C_2 PF13538.6 AIN99900.1 - 1.9e-05 24.4 0.1 4.7e-05 23.1 0.1 1.7 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain Viral_helicase1 PF01443.18 AIN99900.1 - 5.3e-05 23.1 0.0 0.4 10.4 0.0 3.0 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase AAA_16 PF13191.6 AIN99900.1 - 0.018 15.5 0.0 0.061 13.7 0.0 2.0 1 0 0 1 1 1 0 AAA ATPase domain DUF853 PF05872.12 AIN99900.1 - 0.02 13.5 0.2 0.02 13.5 0.2 1.9 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF853) NTPase_1 PF03266.15 AIN99900.1 - 0.031 14.2 1.2 0.23 11.4 0.2 2.4 2 0 0 2 2 2 0 NTPase Mg_chelatase PF01078.21 AIN99900.1 - 0.04 13.3 0.0 0.094 12.1 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI T2SSE PF00437.20 AIN99900.1 - 0.047 12.7 0.2 0.36 9.9 0.1 2.4 3 0 0 3 3 3 0 Type II/IV secretion system protein AAA PF00004.29 AIN99900.1 - 0.054 13.9 0.0 0.16 12.4 0.0 1.8 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) MobB PF03205.14 AIN99900.1 - 0.072 13.0 0.1 0.14 12.1 0.1 1.4 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B NB-ARC PF00931.22 AIN99900.1 - 0.1 11.7 0.1 0.19 10.9 0.1 1.3 1 0 0 1 1 1 0 NB-ARC domain DEAD PF00270.29 AIN99900.1 - 0.2 11.4 0.5 0.85 9.4 0.0 2.0 1 1 0 2 2 2 0 DEAD/DEAH box helicase AAA_7 PF12775.7 AIN99900.1 - 0.22 11.0 0.1 0.42 10.1 0.1 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region SH3_13 PF18335.1 AIN99900.1 - 0.22 11.3 0.0 0.55 10.1 0.0 1.6 1 0 0 1 1 1 0 ATP-dependent RecD-like DNA helicase SH3 domain DUF2075 PF09848.9 AIN99900.1 - 0.39 9.9 3.2 0.21 10.8 0.4 2.0 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_22 PF13401.6 AIN99900.1 - 0.55 10.5 1.8 11 6.3 1.8 2.7 1 1 0 1 1 1 0 AAA domain HEAT_2 PF13646.6 AIN99901.1 - 4e-11 43.1 18.1 4.6e-07 30.1 0.6 6.2 6 1 0 6 6 6 3 HEAT repeats HEAT PF02985.22 AIN99901.1 - 2e-08 33.8 0.6 0.013 15.6 0.0 5.6 4 0 0 4 4 4 3 HEAT repeat TPR_2 PF07719.17 AIN99902.1 - 0.0011 18.9 0.2 0.34 11.1 0.0 2.9 2 0 0 2 2 2 1 Tetratricopeptide repeat SET PF00856.28 AIN99902.1 - 0.0014 19.0 0.0 0.0031 17.9 0.0 1.5 1 0 0 1 1 1 1 SET domain Zn-ribbon_8 PF09723.10 AIN99902.1 - 0.0015 18.6 0.5 0.0043 17.2 0.5 1.8 1 0 0 1 1 1 1 Zinc ribbon domain zf-MYND PF01753.18 AIN99902.1 - 0.0054 16.8 8.0 0.0054 16.8 8.0 2.6 2 0 0 2 2 2 1 MYND finger HypA PF01155.19 AIN99902.1 - 0.15 12.1 0.5 1.4 8.9 0.0 2.4 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Ribosomal_S17e PF00833.18 AIN99903.1 - 1.6e-49 166.9 3.7 2e-49 166.6 3.7 1.1 1 0 0 1 1 1 1 Ribosomal S17 Ribosomal_S17e PF00833.18 AIN99904.1 - 1.6e-49 166.9 3.7 2e-49 166.6 3.7 1.1 1 0 0 1 1 1 1 Ribosomal S17 SF3b1 PF08920.10 AIN99906.1 - 4.1e-07 30.5 0.1 1e-06 29.3 0.1 1.6 1 0 0 1 1 1 1 Splicing factor 3B subunit 1 HEAT_2 PF13646.6 AIN99906.1 - 9.5e-06 25.9 20.6 0.095 13.1 4.3 7.1 5 2 4 9 9 9 2 HEAT repeats UME PF08064.13 AIN99906.1 - 0.00014 21.7 2.7 0.01 15.7 0.1 4.4 4 1 0 4 4 4 1 UME (NUC010) domain CLASP_N PF12348.8 AIN99906.1 - 0.00089 18.9 1.9 0.42 10.1 0.1 4.7 6 0 0 6 6 6 1 CLASP N terminal NUC173 PF08161.12 AIN99906.1 - 0.0018 17.9 5.1 0.32 10.6 0.0 4.7 5 2 1 6 6 6 1 NUC173 domain DRIM PF07539.12 AIN99906.1 - 0.0043 15.4 2.9 0.98 7.6 0.7 3.0 2 1 0 2 2 2 2 Down-regulated in metastasis Adaptin_N PF01602.20 AIN99906.1 - 0.06 11.9 0.6 4.6 5.7 0.0 2.7 2 1 0 2 2 2 0 Adaptin N terminal region DHO_dh PF01180.21 AIN99906.1 - 0.093 11.9 0.1 0.18 11.0 0.1 1.4 1 0 0 1 1 1 0 Dihydroorotate dehydrogenase HEAT_EZ PF13513.6 AIN99906.1 - 0.22 12.1 21.7 4.5 7.9 0.0 7.7 8 1 1 9 9 9 0 HEAT-like repeat HEAT PF02985.22 AIN99906.1 - 2.3 8.7 0.0 2.3 8.7 0.0 6.5 7 0 0 7 7 7 0 HEAT repeat LRR_4 PF12799.7 AIN99907.1 - 1.5e-11 44.3 7.2 4.2e-05 23.8 0.6 4.4 2 2 2 4 4 4 3 Leucine Rich repeats (2 copies) IQ PF00612.27 AIN99907.1 - 2.9e-09 35.9 10.2 1.9e-05 24.0 2.3 2.8 2 0 0 2 2 2 2 IQ calmodulin-binding motif LRR_8 PF13855.6 AIN99907.1 - 1.5e-07 31.0 14.3 0.0016 18.1 0.2 4.2 3 1 2 5 5 5 4 Leucine rich repeat LRR_9 PF14580.6 AIN99907.1 - 0.00063 19.3 1.5 0.021 14.3 0.7 2.7 3 0 0 3 3 3 1 Leucine-rich repeat LRR_1 PF00560.33 AIN99907.1 - 0.0039 17.5 3.8 37 5.4 0.0 4.9 4 0 0 4 4 4 0 Leucine Rich Repeat Glycogen_syn PF05693.13 AIN99907.1 - 0.14 10.7 0.0 0.24 9.9 0.0 1.2 1 0 0 1 1 1 0 Glycogen synthase LRR_6 PF13516.6 AIN99907.1 - 0.18 11.9 9.3 32 4.9 0.1 5.6 7 0 0 7 7 7 0 Leucine Rich repeat ADP_ribosyl_GH PF03747.14 AIN99908.1 - 7.5e-11 42.3 0.2 1.7e-06 28.0 0.1 2.7 2 1 1 3 3 3 2 ADP-ribosylglycohydrolase IQ PF00612.27 AIN99909.1 - 4.2e-24 82.0 87.5 4.7e-05 22.8 2.0 14.3 14 0 0 14 14 14 12 IQ calmodulin-binding motif Fis1_TPR_C PF14853.6 AIN99909.1 - 0.1 12.7 0.0 0.3 11.2 0.0 1.7 1 0 0 1 1 1 0 Fis1 C-terminal tetratricopeptide repeat Adaptin_N PF01602.20 AIN99910.1 - 4.3e-71 240.1 16.0 5.2e-71 239.8 16.0 1.1 1 0 0 1 1 1 1 Adaptin N terminal region COP-gamma_platf PF08752.10 AIN99910.1 - 6.1e-31 107.6 0.1 1.2e-30 106.6 0.1 1.5 1 0 0 1 1 1 1 Coatomer gamma subunit appendage platform subdomain Coatomer_g_Cpla PF16381.5 AIN99910.1 - 2.7e-21 75.9 0.0 5.8e-21 74.8 0.0 1.6 1 0 0 1 1 1 1 Coatomer subunit gamma-1 C-terminal appendage platform HEAT_2 PF13646.6 AIN99910.1 - 2.9e-11 43.6 1.2 2.3e-06 27.9 0.0 4.5 3 2 1 4 4 4 2 HEAT repeats Cnd1 PF12717.7 AIN99910.1 - 0.0002 21.4 11.9 0.0021 18.1 0.3 4.2 2 1 1 3 3 3 2 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 AIN99910.1 - 0.00095 19.2 7.3 5.9 7.4 0.1 5.2 5 0 0 5 5 5 2 HEAT repeat MoaC PF01967.21 AIN99912.1 - 7.7e-21 74.6 0.0 2e-20 73.3 0.0 1.7 2 0 0 2 2 2 1 MoaC family His_Phos_2 PF00328.22 AIN99913.1 - 1.3e-09 37.9 0.4 2.6e-06 27.0 0.0 2.9 2 1 1 3 3 3 2 Histidine phosphatase superfamily (branch 2) His_Phos_1 PF00300.22 AIN99913.1 - 0.06 13.0 0.0 0.24 11.1 0.0 2.1 1 1 0 1 1 1 0 Histidine phosphatase superfamily (branch 1) SelR PF01641.18 AIN99914.1 - 4.5e-39 133.3 0.0 5.3e-39 133.0 0.0 1.0 1 0 0 1 1 1 1 SelR domain zinc_ribbon_10 PF10058.9 AIN99914.1 - 0.0047 16.6 0.3 0.29 10.9 0.0 2.4 2 0 0 2 2 2 1 Predicted integral membrane zinc-ribbon metal-binding protein FYVE PF01363.21 AIN99914.1 - 0.037 14.2 1.1 0.067 13.3 1.1 1.4 1 0 0 1 1 1 0 FYVE zinc finger Yippee-Mis18 PF03226.14 AIN99914.1 - 0.054 13.7 1.2 0.62 10.3 1.2 2.2 1 1 0 1 1 1 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly zf_C2HC_14 PF18574.1 AIN99914.1 - 0.094 12.5 1.5 0.11 12.3 0.1 1.8 2 0 0 2 2 2 0 C2HC Zing finger domain Metallophos PF00149.28 AIN99915.1 - 5.8e-32 111.8 0.1 7.3e-32 111.5 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase zf_UBZ PF18439.1 AIN99915.1 - 0.13 11.9 0.1 12 5.6 0.0 2.3 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger VitD-bind_III PF09164.10 AIN99915.1 - 0.15 12.0 0.9 0.35 10.9 0.9 1.5 1 0 0 1 1 1 0 Vitamin D binding protein, domain III COX15-CtaA PF02628.15 AIN99916.1 - 9.3e-103 343.7 9.3 1.1e-102 343.5 9.3 1.0 1 0 0 1 1 1 1 Cytochrome oxidase assembly protein 2OG-FeII_Oxy_2 PF13532.6 AIN99919.1 - 0.0017 18.6 0.0 0.0023 18.2 0.0 1.2 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily APG12 PF04110.13 AIN99920.1 - 0.049 14.0 0.0 0.26 11.7 0.0 2.0 1 1 1 2 2 2 0 Ubiquitin-like autophagy protein Apg12 DNA_processg_A PF02481.15 AIN99920.1 - 0.1 11.8 0.0 0.13 11.5 0.0 1.1 1 0 0 1 1 1 0 DNA recombination-mediator protein A DUF179 PF02622.15 AIN99921.1 - 2.6e-06 27.5 0.0 7.4e-06 26.0 0.0 1.7 1 0 0 1 1 1 1 Uncharacterized ACR, COG1678 WD40 PF00400.32 AIN99922.1 - 2.2e-45 151.7 18.9 1.2e-07 32.3 0.1 7.1 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 AIN99922.1 - 9.7e-13 48.2 0.4 0.016 15.5 0.0 4.4 1 1 4 5 5 5 5 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 AIN99922.1 - 2.3e-08 33.2 3.8 0.022 13.4 0.0 3.9 2 2 2 4 4 4 3 Nucleoporin Nup120/160 eIF2A PF08662.11 AIN99922.1 - 2.8e-06 27.3 0.0 0.054 13.4 0.0 3.3 1 1 2 3 3 3 3 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 AIN99922.1 - 9.3e-05 21.5 1.5 0.012 14.6 0.6 3.6 1 1 3 4 4 4 1 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 AIN99922.1 - 0.00033 20.5 0.2 1.6 8.8 0.1 4.8 5 1 0 5 5 5 1 WD40-like Beta Propeller Repeat WD40_like PF17005.5 AIN99922.1 - 0.0093 15.3 0.0 0.013 14.8 0.0 1.3 1 0 0 1 1 1 1 WD40-like domain Cytochrom_D1 PF02239.16 AIN99922.1 - 0.018 13.6 0.0 1.3 7.5 0.0 2.4 2 1 0 2 2 2 0 Cytochrome D1 heme domain PQQ_2 PF13360.6 AIN99922.1 - 0.02 14.5 0.1 0.1 12.2 0.0 2.1 1 1 0 2 2 2 0 PQQ-like domain Coatomer_WDAD PF04053.14 AIN99922.1 - 0.17 10.9 0.0 0.51 9.3 0.0 1.6 1 1 1 2 2 2 0 Coatomer WD associated region WD40 PF00400.32 AIN99923.1 - 2.2e-45 151.7 18.9 1.2e-07 32.3 0.1 7.1 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 AIN99923.1 - 9.7e-13 48.2 0.4 0.016 15.5 0.0 4.4 1 1 4 5 5 5 5 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 AIN99923.1 - 2.3e-08 33.2 3.8 0.022 13.4 0.0 3.9 2 2 2 4 4 4 3 Nucleoporin Nup120/160 eIF2A PF08662.11 AIN99923.1 - 2.8e-06 27.3 0.0 0.054 13.4 0.0 3.3 1 1 2 3 3 3 3 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 AIN99923.1 - 9.3e-05 21.5 1.5 0.012 14.6 0.6 3.6 1 1 3 4 4 4 1 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 AIN99923.1 - 0.00033 20.5 0.2 1.6 8.8 0.1 4.8 5 1 0 5 5 5 1 WD40-like Beta Propeller Repeat WD40_like PF17005.5 AIN99923.1 - 0.0093 15.3 0.0 0.013 14.8 0.0 1.3 1 0 0 1 1 1 1 WD40-like domain Cytochrom_D1 PF02239.16 AIN99923.1 - 0.018 13.6 0.0 1.3 7.5 0.0 2.4 2 1 0 2 2 2 0 Cytochrome D1 heme domain PQQ_2 PF13360.6 AIN99923.1 - 0.02 14.5 0.1 0.1 12.2 0.0 2.1 1 1 0 2 2 2 0 PQQ-like domain Coatomer_WDAD PF04053.14 AIN99923.1 - 0.17 10.9 0.0 0.51 9.3 0.0 1.6 1 1 1 2 2 2 0 Coatomer WD associated region GCP_C_terminal PF04130.13 AIN99924.1 - 1e-40 140.2 9.0 1.9e-40 139.2 9.0 1.5 1 0 0 1 1 1 1 Gamma tubulin complex component C-terminal GCP_N_terminal PF17681.1 AIN99924.1 - 1.9e-31 109.8 1.4 2.8e-31 109.3 0.0 1.9 2 1 0 2 2 2 1 Gamma tubulin complex component N-terminal HSP70 PF00012.20 AIN99925.1 - 3.9e-262 870.8 3.9 4.4e-262 870.6 3.9 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 AIN99925.1 - 1.6e-13 50.2 0.0 2.1e-12 46.5 0.0 2.1 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.16 AIN99925.1 - 0.0097 15.6 0.0 0.066 12.9 0.0 2.2 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain DDR PF08841.10 AIN99925.1 - 0.078 12.0 0.5 2 7.3 0.2 2.2 2 0 0 2 2 2 0 Diol dehydratase reactivase ATPase-like domain DUF4854 PF16146.5 AIN99925.1 - 0.2 12.0 3.5 0.53 10.6 3.5 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4854) Beta-lactamase PF00144.24 AIN99927.1 - 8.7e-12 44.9 0.1 2.2e-11 43.6 0.1 1.6 1 1 0 1 1 1 1 Beta-lactamase FlgT_N PF16548.5 AIN99928.1 - 0.058 14.0 0.2 0.11 13.1 0.2 1.4 1 0 0 1 1 1 0 Flagellar assembly protein T, N-terminal domain HSP70 PF00012.20 AIN99929.1 - 3.5e-193 643.1 5.9 4e-193 642.9 5.9 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 AIN99929.1 - 1e-18 67.3 0.6 1.3e-14 53.8 0.1 2.5 2 0 0 2 2 2 2 MreB/Mbl protein FtsA PF14450.6 AIN99929.1 - 0.00023 21.5 4.7 0.017 15.5 0.0 3.5 3 2 0 3 3 3 2 Cell division protein FtsA ATG16 PF08614.11 AIN99931.1 - 2.6 8.2 7.2 2.8 8.1 5.0 1.8 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) DUF3348 PF11828.8 AIN99932.1 - 0.012 15.3 0.4 0.089 12.5 0.0 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3348) F-box PF00646.33 AIN99932.1 - 0.034 14.0 0.0 0.09 12.7 0.0 1.7 1 0 0 1 1 1 0 F-box domain Ldh_1_N PF00056.23 AIN99933.1 - 5.6e-30 104.3 0.1 8.3e-30 103.7 0.1 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.18 AIN99933.1 - 4.4e-26 91.8 0.0 7.3e-26 91.1 0.0 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Sigma70_r4_2 PF08281.12 AIN99934.1 - 0.21 11.3 0.9 6.9 6.4 0.0 2.9 3 0 0 3 3 3 0 Sigma-70, region 4 AAA_6 PF12774.7 AIN99935.1 - 1.7e-149 497.2 0.0 5.4e-149 495.6 0.0 1.9 2 0 0 2 2 2 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 AIN99935.1 - 9e-105 351.0 0.2 9e-105 351.0 0.2 3.8 4 0 0 4 4 4 1 Dynein heavy chain, N-terminal region 2 AAA_8 PF12780.7 AIN99935.1 - 1.1e-100 336.3 0.0 3.9e-100 334.5 0.0 2.0 2 0 0 2 2 2 1 P-loop containing dynein motor region D4 Dynein_C PF18199.1 AIN99935.1 - 1.7e-80 270.5 0.0 7.9e-79 265.0 0.0 3.8 4 0 0 4 4 4 1 Dynein heavy chain C-terminal domain AAA_9 PF12781.7 AIN99935.1 - 4.9e-76 254.7 0.1 4.9e-76 254.7 0.1 2.7 3 0 0 3 3 2 1 ATP-binding dynein motor region AAA_7 PF12775.7 AIN99935.1 - 2.6e-71 238.9 0.4 6.2e-65 218.1 0.0 4.1 4 0 0 4 4 4 3 P-loop containing dynein motor region AAA_lid_11 PF18198.1 AIN99935.1 - 8.2e-55 185.1 0.0 2.1e-54 183.7 0.0 1.8 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain Dynein_heavy PF03028.15 AIN99935.1 - 8.5e-44 148.5 0.1 1.2e-41 141.5 0.0 4.0 3 0 0 3 3 3 1 Dynein heavy chain region D6 P-loop domain MT PF12777.7 AIN99935.1 - 3e-40 138.3 10.7 5.6e-40 137.4 10.7 1.5 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor Dynein_AAA_lid PF17852.1 AIN99935.1 - 3.4e-25 88.6 0.0 1.5e-24 86.6 0.0 2.2 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain AAA_5 PF07728.14 AIN99935.1 - 4.4e-25 88.3 0.0 4.6e-07 29.9 0.0 6.5 6 1 0 6 6 6 4 AAA domain (dynein-related subfamily) AAA_lid_1 PF17857.1 AIN99935.1 - 1e-11 44.9 0.1 3.4e-11 43.2 0.0 2.0 2 0 0 2 2 1 1 AAA+ lid domain AAA PF00004.29 AIN99935.1 - 1.7e-09 38.2 0.6 0.047 14.1 0.0 5.2 4 0 0 4 4 4 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 AIN99935.1 - 1.5e-07 32.0 4.9 3.3 8.1 0.0 7.5 6 1 1 7 7 6 2 AAA ATPase domain AAA_18 PF13238.6 AIN99935.1 - 2.5e-05 24.8 0.0 0.083 13.4 0.0 4.2 4 0 0 4 4 3 1 AAA domain AAA_22 PF13401.6 AIN99935.1 - 3.4e-05 24.2 4.9 3 8.1 0.0 5.9 5 0 0 5 5 4 1 AAA domain DUF853 PF05872.12 AIN99935.1 - 0.0012 17.5 0.5 0.051 12.2 0.1 2.6 2 0 0 2 2 2 1 Bacterial protein of unknown function (DUF853) Sigma54_activat PF00158.26 AIN99935.1 - 0.0013 18.4 0.4 0.58 9.8 0.0 3.8 4 0 0 4 4 4 1 Sigma-54 interaction domain RNA_helicase PF00910.22 AIN99935.1 - 0.0017 18.7 0.0 0.38 11.2 0.0 4.0 3 0 0 3 3 3 1 RNA helicase AAA_14 PF13173.6 AIN99935.1 - 0.0025 17.9 0.0 1.7 8.6 0.0 3.3 2 0 0 2 2 2 1 AAA domain ResIII PF04851.15 AIN99935.1 - 0.024 14.6 0.9 1 9.3 0.0 3.5 4 0 0 4 4 3 0 Type III restriction enzyme, res subunit NACHT PF05729.12 AIN99935.1 - 0.046 13.6 1.7 9.9 6.0 0.0 4.1 4 0 0 4 4 4 0 NACHT domain AAA_33 PF13671.6 AIN99935.1 - 0.11 12.7 1.7 61 3.8 0.0 4.5 4 0 0 4 4 3 0 AAA domain AAA_19 PF13245.6 AIN99935.1 - 0.62 10.4 4.0 59 4.0 0.0 4.2 4 0 0 4 4 3 0 AAA domain SRP54 PF00448.22 AIN99935.1 - 2.1 7.9 5.1 21 4.7 0.1 3.9 4 0 0 4 4 4 0 SRP54-type protein, GTPase domain DUF1672 PF07901.11 AIN99935.1 - 2.2 7.5 4.3 4.9 6.4 0.8 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF1672) Dor1 PF04124.12 AIN99937.1 - 6e-24 84.3 3.1 7.7e-24 84.0 3.1 1.1 1 0 0 1 1 1 1 Dor1-like family Exo84_C PF16528.5 AIN99937.1 - 1.5e-05 24.9 0.1 3.2e-05 23.8 0.0 1.6 1 1 0 1 1 1 1 Exocyst component 84 C-terminal ELFV_dehydrog PF00208.21 AIN99938.1 - 1.7e-85 286.7 3.4 2.3e-85 286.2 3.4 1.1 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ELFV_dehydrog_N PF02812.18 AIN99938.1 - 1.2e-49 167.5 0.0 3.4e-49 166.0 0.0 1.8 1 0 0 1 1 1 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain NAD_binding_7 PF13241.6 AIN99938.1 - 0.002 18.6 0.1 0.0036 17.7 0.1 1.4 1 0 0 1 1 1 1 Putative NAD(P)-binding Na_sulph_symp PF00939.19 AIN99940.1 - 1.5e-16 60.5 48.7 7.4e-16 58.2 48.7 2.5 1 1 0 1 1 1 1 Sodium:sulfate symporter transmembrane region CitMHS PF03600.16 AIN99940.1 - 1.5e-15 57.2 49.6 1.5e-15 57.2 49.6 1.7 1 1 1 2 2 2 1 Citrate transporter SPX PF03105.19 AIN99940.1 - 1.4e-06 28.5 8.1 3.5e-06 27.2 0.5 2.5 1 1 2 3 3 3 2 SPX domain zf-CCCH_4 PF18044.1 AIN99942.1 - 0.014 15.1 0.6 0.014 15.1 0.6 2.8 2 1 1 3 3 3 0 CCCH-type zinc finger zf-CCCH PF00642.24 AIN99942.1 - 0.31 11.0 8.1 3.7 7.6 0.3 2.7 3 0 0 3 3 3 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 AIN99942.1 - 2.2 8.5 9.0 0.18 11.9 2.3 2.4 2 0 0 2 2 2 0 Zinc finger domain WD40 PF00400.32 AIN99943.1 - 0.028 15.3 12.0 1.7 9.6 1.3 5.0 5 0 0 5 5 5 0 WD domain, G-beta repeat DUF2828 PF11443.8 AIN99943.1 - 0.28 9.2 0.0 5.3 5.0 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF2828) dCache_2 PF08269.11 AIN99946.1 - 0.13 11.4 1.7 0.16 11.1 0.0 1.8 1 1 1 2 2 2 0 Cache domain Pkinase PF00069.25 AIN99947.1 - 7e-46 156.7 0.0 8.6e-46 156.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 AIN99947.1 - 4.9e-27 94.8 0.0 6.2e-27 94.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 AIN99947.1 - 0.00021 20.2 0.0 0.0003 19.7 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 AIN99947.1 - 0.00022 20.7 0.0 0.00036 20.0 0.0 1.2 1 0 0 1 1 1 1 Kinase-like SMRP1 PF15181.6 AIN99947.1 - 0.058 13.0 0.1 0.086 12.4 0.1 1.2 1 0 0 1 1 1 0 Spermatid-specific manchette-related protein 1 Acetyltransf_1 PF00583.25 AIN99948.1 - 2e-12 47.4 0.0 2.3e-12 47.2 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 AIN99948.1 - 2.8e-08 33.7 0.0 3.6e-08 33.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 AIN99948.1 - 5.4e-08 33.1 0.0 8.1e-08 32.6 0.0 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 AIN99948.1 - 0.0037 17.3 0.0 0.0049 17.0 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 AIN99948.1 - 0.0088 16.2 0.0 0.014 15.5 0.0 1.3 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase CARD PF00619.21 AIN99948.1 - 0.055 13.5 0.1 0.11 12.5 0.1 1.5 1 0 0 1 1 1 0 Caspase recruitment domain Cytochrome_CBB3 PF13442.6 AIN99950.1 - 3.8 7.9 8.1 3.1 8.2 0.4 2.6 2 0 0 2 2 2 0 Cytochrome C oxidase, cbb3-type, subunit III ECH_1 PF00378.20 AIN99951.1 - 2e-36 125.6 0.0 2.5e-36 125.3 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 AIN99951.1 - 1.3e-10 41.3 0.0 1.8e-10 40.8 0.0 1.4 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase SPT16 PF08644.11 AIN99952.1 - 4.8e-31 108.0 0.0 1.4e-30 106.4 0.0 1.9 1 0 0 1 1 1 1 FACT complex subunit (SPT16/CDC68) Peptidase_M24 PF00557.24 AIN99952.1 - 6.5e-14 52.1 0.0 1.2e-13 51.2 0.0 1.5 1 0 0 1 1 1 1 Metallopeptidase family M24 Rtt106 PF08512.12 AIN99952.1 - 1.7e-08 34.7 0.4 4.9e-08 33.3 0.0 2.0 2 0 0 2 2 2 1 Histone chaperone Rttp106-like CoaE PF01121.20 AIN99952.1 - 0.07 12.8 0.1 0.15 11.7 0.1 1.5 1 0 0 1 1 1 0 Dephospho-CoA kinase KR PF08659.10 AIN99952.1 - 0.085 12.8 0.6 0.19 11.6 0.6 1.6 1 0 0 1 1 1 0 KR domain SAPS PF04499.15 AIN99952.1 - 0.14 10.9 1.7 0.24 10.1 1.7 1.3 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Nop14 PF04147.12 AIN99952.1 - 3.6 5.7 17.8 6.3 4.9 17.8 1.3 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 AIN99952.1 - 4.6 5.4 15.3 9.6 4.4 15.3 1.5 1 0 0 1 1 1 0 CDC45-like protein Sporozoite_P67 PF05642.11 AIN99952.1 - 7.5 4.5 6.8 12 3.9 6.8 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Ribosomal_L3 PF00297.22 AIN99953.1 - 9.3e-08 31.4 0.1 1.5e-07 30.8 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L3 TPR_2 PF07719.17 AIN99953.1 - 0.18 12.0 0.7 0.51 10.6 0.7 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat GSP_synth PF03738.14 AIN99954.1 - 0.059 12.5 0.0 0.099 11.8 0.0 1.3 1 0 0 1 1 1 0 Glutathionylspermidine synthase preATP-grasp GP3_package PF16677.5 AIN99954.1 - 0.16 12.1 0.0 0.28 11.4 0.0 1.4 1 0 0 1 1 1 0 DNA-packaging protein gp3 tRNA-synt_1b PF00579.25 AIN99956.1 - 4e-19 69.0 0.0 1.3e-18 67.3 0.0 1.8 1 1 0 1 1 1 1 tRNA synthetases class I (W and Y) ATG11 PF10377.9 AIN99956.1 - 0.12 12.4 0.0 0.29 11.2 0.0 1.6 1 0 0 1 1 1 0 Autophagy-related protein 11 SNARE PF05739.19 AIN99957.1 - 4.5e-06 26.6 0.7 1.2e-05 25.2 0.7 1.8 1 0 0 1 1 1 1 SNARE domain DUF1664 PF07889.12 AIN99957.1 - 0.0034 17.4 3.3 0.58 10.2 0.2 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF1664) Dynactin_p22 PF07426.11 AIN99957.1 - 0.02 14.8 1.4 0.048 13.5 0.1 2.2 2 1 0 2 2 2 0 Dynactin subunit p22 Synaptobrevin PF00957.21 AIN99957.1 - 0.034 13.9 3.5 0.059 13.2 0.6 2.3 2 0 0 2 2 2 0 Synaptobrevin Prominin PF05478.11 AIN99957.1 - 0.057 11.4 5.0 0.073 11.0 5.0 1.2 1 0 0 1 1 1 0 Prominin BLOC1S3 PF15753.5 AIN99957.1 - 0.063 13.4 0.7 0.063 13.4 0.7 2.9 1 1 2 3 3 3 0 Biogenesis of lysosome-related organelles complex 1 subunit 3 DUF4777 PF16007.5 AIN99957.1 - 0.15 12.4 0.5 2 8.7 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4777) DUF948 PF06103.11 AIN99957.1 - 0.23 11.7 1.8 7.3 6.9 0.1 2.9 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) RmuC PF02646.16 AIN99957.1 - 0.29 10.2 6.9 0.084 12.0 0.9 2.6 2 1 1 3 3 3 0 RmuC family Syntaxin_2 PF14523.6 AIN99957.1 - 1.9 8.9 12.9 0.62 10.5 1.5 2.7 3 0 0 3 3 3 0 Syntaxin-like protein Jnk-SapK_ap_N PF09744.9 AIN99957.1 - 4.4 7.5 14.2 0.7 10.1 5.1 2.6 1 1 2 3 3 3 0 JNK_SAPK-associated protein-1 MutS_III PF05192.18 AIN99957.1 - 6.2 7.0 12.0 33 4.6 11.7 2.0 1 1 0 1 1 1 0 MutS domain III Sen15 PF09631.10 AIN99958.1 - 0.089 13.1 0.0 0.11 12.9 0.0 1.2 1 0 0 1 1 1 0 Sen15 protein Ras PF00071.22 AIN99959.1 - 2.8e-34 118.1 0.2 3.3e-34 117.8 0.2 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 AIN99959.1 - 1.8e-18 66.9 0.0 2.5e-18 66.5 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 AIN99959.1 - 1.7e-10 40.6 0.0 2.2e-10 40.2 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 AIN99959.1 - 1.6e-06 27.7 0.1 2e-06 27.3 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 AIN99959.1 - 5.4e-05 22.8 0.3 0.00026 20.6 0.2 1.8 1 1 0 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 AIN99959.1 - 0.0032 17.5 0.0 0.0053 16.8 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase PduV-EutP PF10662.9 AIN99959.1 - 0.0041 16.9 0.0 0.085 12.6 0.0 2.1 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation G-alpha PF00503.20 AIN99959.1 - 0.026 13.7 0.0 0.26 10.4 0.0 2.2 2 1 1 3 3 3 0 G-protein alpha subunit WD40 PF00400.32 AIN99960.1 - 0.0015 19.3 0.9 26 5.9 0.0 5.2 5 0 0 5 5 5 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 AIN99960.1 - 0.006 16.9 0.1 4.9 7.5 0.0 3.9 3 1 1 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain DUF2139 PF09910.9 AIN99960.1 - 0.1 11.8 0.0 0.29 10.3 0.0 1.7 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2139) tify PF06200.14 AIN99960.1 - 0.28 10.5 0.8 3.6 7.0 0.1 2.6 3 0 0 3 3 3 0 tify domain DHR-2 PF06920.13 AIN99961.1 - 8e-20 71.0 4.4 1.2e-16 60.5 0.1 2.7 3 0 0 3 3 3 2 Dock homology region 2 DOCK-C2 PF14429.6 AIN99961.1 - 3.6e-18 66.1 0.0 8.2e-18 64.9 0.0 1.6 1 0 0 1 1 1 1 C2 domain in Dock180 and Zizimin proteins RPN1_RPN2_N PF17781.1 AIN99963.1 - 1.4e-74 251.3 0.0 3.1e-74 250.2 0.1 1.5 2 0 0 2 2 2 1 RPN1/RPN2 N-terminal domain PC_rep PF01851.22 AIN99963.1 - 4e-22 77.5 14.3 1.8e-05 24.9 0.0 8.6 9 0 0 9 9 9 4 Proteasome/cyclosome repeat RPN1_C PF18051.1 AIN99963.1 - 2.3e-19 69.2 0.0 4.2e-19 68.3 0.0 1.4 1 0 0 1 1 1 1 26S proteasome non-ATPase regulatory subunit RPN1 C-terminal HEAT_2 PF13646.6 AIN99963.1 - 0.00066 20.0 3.3 0.46 10.9 0.1 4.7 4 2 1 5 5 5 1 HEAT repeats IFRD PF05004.13 AIN99963.1 - 0.012 14.7 0.5 0.039 13.1 0.1 2.2 2 0 0 2 2 2 0 Interferon-related developmental regulator (IFRD) CHASE6_C PF17150.4 AIN99963.1 - 0.069 13.8 0.0 5.1 7.8 0.0 2.9 1 1 1 2 2 2 0 C-terminal domain of two-partite extracellular sensor domain PhrC_PhrF PF11131.8 AIN99963.1 - 0.11 12.0 0.2 0.41 10.3 0.2 2.0 1 0 0 1 1 1 0 Rap-phr extracellular signalling HEAT_EZ PF13513.6 AIN99963.1 - 0.19 12.3 5.4 27 5.4 0.1 4.7 5 0 0 5 5 5 0 HEAT-like repeat IQ PF00612.27 AIN99964.1 - 0.037 13.8 11.1 0.077 12.8 2.4 2.9 2 0 0 2 2 2 0 IQ calmodulin-binding motif PreAtp-grasp PF18604.1 AIN99964.1 - 0.08 12.6 0.4 0.22 11.2 0.4 1.6 1 0 0 1 1 1 0 Pre ATP-grasp domain RNA_pol_A_bac PF01000.26 AIN99965.1 - 1e-19 70.9 0.0 1.8e-19 70.2 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.24 AIN99965.1 - 3.5e-16 58.4 0.0 5.3e-16 57.8 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Fer4_9 PF13187.6 AIN99965.1 - 0.079 13.1 0.9 0.079 13.1 0.9 2.1 2 0 0 2 2 2 0 4Fe-4S dicluster domain TPR_19 PF14559.6 AIN99966.1 - 2.3e-13 50.4 10.5 0.00076 19.9 0.1 5.6 5 1 0 6 6 5 4 Tetratricopeptide repeat TPR_2 PF07719.17 AIN99966.1 - 7.3e-11 41.3 18.2 0.00018 21.4 0.0 8.7 9 0 0 9 9 8 3 Tetratricopeptide repeat ANAPC3 PF12895.7 AIN99966.1 - 2.9e-10 40.2 11.9 1.7e-07 31.3 3.7 3.8 3 0 0 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.6 AIN99966.1 - 5.9e-10 39.3 13.6 0.0042 17.4 0.9 6.7 5 2 1 6 6 6 3 Tetratricopeptide repeat TPR_1 PF00515.28 AIN99966.1 - 5.1e-08 32.4 11.9 0.038 13.8 0.0 7.0 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_16 PF13432.6 AIN99966.1 - 1.5e-05 25.6 3.7 0.0027 18.3 0.1 4.6 3 2 1 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.6 AIN99966.1 - 2.4e-05 24.8 12.9 0.033 15.0 0.0 6.8 7 2 2 9 9 6 2 Tetratricopeptide repeat TPR_8 PF13181.6 AIN99966.1 - 0.00014 21.8 8.3 0.43 10.9 0.1 6.5 7 0 0 7 7 6 1 Tetratricopeptide repeat HrpB1_HrpK PF09613.10 AIN99966.1 - 0.00025 20.7 0.6 0.031 13.9 0.0 3.7 2 1 1 3 3 3 1 Bacterial type III secretion protein (HrpB1_HrpK) TPR_7 PF13176.6 AIN99966.1 - 0.0025 17.7 9.0 1.4 9.1 0.1 6.6 7 0 0 7 7 6 1 Tetratricopeptide repeat TPR_3 PF07720.12 AIN99966.1 - 0.0085 16.1 0.2 0.0085 16.1 0.2 3.5 4 0 0 4 4 3 1 Tetratricopeptide repeat SRP_TPR_like PF17004.5 AIN99966.1 - 0.0089 16.0 14.7 0.45 10.5 3.2 4.0 3 1 2 5 5 5 3 Putative TPR-like repeat PPR PF01535.20 AIN99966.1 - 0.01 16.0 6.9 17 6.0 0.0 4.9 5 0 0 5 5 4 0 PPR repeat TPR_6 PF13174.6 AIN99966.1 - 0.013 16.1 19.5 0.019 15.6 0.0 6.7 9 0 0 9 9 6 0 Tetratricopeptide repeat N1221 PF07923.13 AIN99966.1 - 0.019 14.2 0.1 0.042 13.0 0.1 1.7 1 0 0 1 1 1 0 N1221-like protein Sec16_C PF12931.7 AIN99966.1 - 0.056 13.1 1.4 0.93 9.1 0.4 2.5 2 0 0 2 2 2 0 Sec23-binding domain of Sec16 DUF1664 PF07889.12 AIN99966.1 - 0.14 12.2 0.3 5.1 7.2 0.1 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) DUF3829 PF12889.7 AIN99966.1 - 0.41 10.1 4.4 1.3 8.4 0.4 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF3829) TPR_17 PF13431.6 AIN99966.1 - 1.3 9.5 4.3 1.3e+02 3.3 0.2 4.8 5 0 0 5 5 3 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 AIN99966.1 - 2.6 8.2 16.8 9.8 6.3 0.2 4.9 3 1 2 5 5 5 0 Fis1 C-terminal tetratricopeptide repeat TPR_9 PF13371.6 AIN99966.1 - 5.4 7.3 7.5 12 6.1 0.0 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat IPP-2 PF04979.14 AIN99968.1 - 1.1e-20 74.7 4.4 1.4e-20 74.4 4.4 1.1 1 0 0 1 1 1 1 Protein phosphatase inhibitor 2 (IPP-2) zf-RanBP PF00641.18 AIN99969.1 - 0.0083 15.4 7.1 0.0083 15.4 7.1 1.7 2 0 0 2 2 2 1 Zn-finger in Ran binding protein and others RRM_1 PF00076.22 AIN99969.1 - 0.023 14.5 0.0 0.047 13.5 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF4658 PF15555.6 AIN99969.1 - 0.072 13.2 0.1 0.15 12.2 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4658) F-box_5 PF18511.1 AIN99970.1 - 0.15 11.7 0.2 0.81 9.3 0.0 2.2 2 0 0 2 2 2 0 F-box P19Arf_N PF07392.12 AIN99970.1 - 9.6 6.7 9.7 8.7 6.9 6.6 2.7 2 0 0 2 2 2 0 Cyclin-dependent kinase inhibitor 2a p19Arf N-terminus SNF2_N PF00176.23 AIN99971.1 - 2e-30 105.7 0.1 3.5e-30 104.9 0.1 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 AIN99971.1 - 6.2e-11 42.6 0.3 1.4e-10 41.5 0.0 1.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 AIN99971.1 - 8.9e-07 29.1 0.0 0.0075 16.3 0.0 2.6 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit SWI2_SNF2 PF18766.1 AIN99971.1 - 0.00021 21.1 0.2 0.0024 17.6 0.0 2.2 2 0 0 2 2 2 1 SWI2/SNF2 ATPase ERCC3_RAD25_C PF16203.5 AIN99971.1 - 0.00034 19.9 0.0 0.00067 19.0 0.0 1.4 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase AAA_22 PF13401.6 AIN99971.1 - 0.01 16.1 0.1 0.055 13.7 0.1 2.3 2 0 0 2 2 2 0 AAA domain TruB_C_2 PF16198.5 AIN99971.1 - 0.019 15.1 0.9 0.078 13.1 0.9 2.1 1 0 0 1 1 1 0 tRNA pseudouridylate synthase B C-terminal domain DUF2207 PF09972.9 AIN99972.1 - 0.0041 16.0 0.7 0.012 14.5 0.7 1.7 1 1 0 1 1 1 1 Predicted membrane protein (DUF2207) Remorin_C PF03763.13 AIN99972.1 - 0.0053 16.6 0.6 0.011 15.6 0.6 1.6 1 0 0 1 1 1 1 Remorin, C-terminal region DHHC PF01529.20 AIN99972.1 - 1.1 9.4 3.5 2.1 8.5 2.3 1.8 2 0 0 2 2 2 0 DHHC palmitoyltransferase BRI3BP PF14965.6 AIN99972.1 - 4.9 6.6 7.6 2.5 7.6 0.0 2.5 2 1 0 2 2 2 0 Negative regulator of p53/TP53 Sec23_trunk PF04811.15 AIN99973.1 - 4.8e-43 147.5 0.0 8.3e-43 146.7 0.0 1.3 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_BS PF08033.12 AIN99973.1 - 2.2e-20 73.2 0.0 5.4e-20 71.9 0.0 1.7 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.15 AIN99973.1 - 1.7e-12 47.2 2.4 1.7e-12 47.2 2.4 1.9 2 0 0 2 2 2 1 Sec23/Sec24 zinc finger Sec23_helical PF04815.15 AIN99973.1 - 4.8e-10 39.2 0.0 1e-09 38.2 0.0 1.5 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Gelsolin PF00626.22 AIN99973.1 - 0.14 12.0 0.0 0.42 10.6 0.0 1.7 1 0 0 1 1 1 0 Gelsolin repeat DUF4893 PF16233.5 AIN99973.1 - 0.16 11.5 0.0 0.36 10.4 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4893) RasGEF_N_2 PF14663.6 AIN99974.1 - 0.16 12.4 0.0 0.32 11.4 0.0 1.5 1 0 0 1 1 1 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain RIO1 PF01163.22 AIN99975.1 - 3.8e-65 219.0 0.6 6e-65 218.4 0.0 1.6 2 0 0 2 2 2 1 RIO1 family APH PF01636.23 AIN99975.1 - 0.097 12.6 0.3 0.65 9.9 0.1 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family CDC45 PF02724.14 AIN99975.1 - 1.4 7.2 13.8 1.9 6.7 13.8 1.2 1 0 0 1 1 1 0 CDC45-like protein DIOX_N PF14226.6 AIN99976.1 - 7.9e-35 120.2 0.0 1.3e-34 119.5 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 AIN99976.1 - 6.3e-25 87.6 0.0 1.2e-24 86.7 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DUF2914 PF11141.8 AIN99976.1 - 0.11 12.3 0.0 0.3 10.9 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2914) TTL PF03133.15 AIN99977.1 - 7.6e-42 143.4 0.0 4.8e-18 65.3 0.0 3.2 3 0 0 3 3 3 3 Tubulin-tyrosine ligase family ATPgrasp_ST PF14397.6 AIN99977.1 - 0.0032 16.8 0.0 1 8.5 0.0 2.2 2 0 0 2 2 2 2 Sugar-transfer associated ATP-grasp zf-C2HC_2 PF13913.6 AIN99979.1 - 9.1e-17 60.5 8.0 1.4e-09 37.6 1.4 2.4 2 0 0 2 2 2 2 zinc-finger of a C2HC-type zf-Di19 PF05605.12 AIN99979.1 - 0.0002 21.6 2.6 0.047 14.0 0.5 2.6 2 0 0 2 2 2 1 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_4 PF13894.6 AIN99979.1 - 0.00026 21.6 5.7 0.095 13.6 1.1 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-RING_7 PF02591.15 AIN99979.1 - 0.016 15.4 3.8 1.7 8.9 0.1 2.8 3 0 0 3 3 2 0 C4-type zinc ribbon domain Zn-ribbon_8 PF09723.10 AIN99979.1 - 0.031 14.4 5.8 0.79 9.9 0.2 2.8 2 1 1 3 3 3 0 Zinc ribbon domain zf_UBZ PF18439.1 AIN99979.1 - 0.05 13.2 1.1 4.7 6.9 0.1 2.5 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger zf-ribbon_3 PF13248.6 AIN99979.1 - 0.057 12.8 3.6 2.6 7.6 0.1 3.2 3 0 0 3 3 3 0 zinc-ribbon domain Lar_restr_allev PF14354.6 AIN99979.1 - 0.058 13.8 4.3 0.4 11.1 0.3 2.6 2 0 0 2 2 2 0 Restriction alleviation protein Lar Nairovirus_M PF07948.11 AIN99979.1 - 0.06 11.6 3.5 0.71 8.0 0.6 2.1 2 0 0 2 2 2 0 Nairovirus M polyprotein-like zf-C2H2 PF00096.26 AIN99979.1 - 0.071 13.6 5.8 2 9.0 2.1 2.6 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-CHCC PF10276.9 AIN99979.1 - 0.1 12.6 1.2 7.1 6.8 0.1 2.6 2 0 0 2 2 2 0 Zinc-finger domain zf-FPG_IleRS PF06827.14 AIN99979.1 - 0.16 11.9 10.0 1 9.3 2.4 2.6 2 0 0 2 2 2 0 Zinc finger found in FPG and IleRS TRAF6_Z2 PF18048.1 AIN99979.1 - 0.17 12.0 1.2 12 6.1 0.4 2.6 2 0 0 2 2 2 0 TNF receptor-associated factor 6 zinc finger 2 zinc_ribbon_9 PF14369.6 AIN99979.1 - 0.17 12.1 8.0 3.3 8.1 0.3 3.5 4 0 0 4 4 3 0 zinc-ribbon zf-C2H2_11 PF16622.5 AIN99979.1 - 0.19 11.5 2.4 14 5.5 0.2 2.4 2 0 0 2 2 2 0 zinc-finger C2H2-type zf-H2C2_2 PF13465.6 AIN99979.1 - 0.27 11.8 1.1 26 5.4 0.1 2.7 2 0 0 2 2 2 0 Zinc-finger double domain Sgf11 PF08209.11 AIN99979.1 - 0.28 10.8 3.2 1.9 8.1 0.2 2.4 2 0 0 2 2 2 0 Sgf11 (transcriptional regulation protein) DUF2256 PF10013.9 AIN99979.1 - 0.44 10.7 5.6 3.2 7.9 0.1 3.0 3 0 0 3 3 2 0 Uncharacterized protein conserved in bacteria (DUF2256) Zn_Tnp_IS1595 PF12760.7 AIN99979.1 - 0.55 10.2 3.8 9.2 6.3 1.1 2.5 2 0 0 2 2 2 0 Transposase zinc-ribbon domain ADK_lid PF05191.14 AIN99979.1 - 0.59 10.2 3.2 20 5.3 0.1 2.6 2 0 0 2 2 2 0 Adenylate kinase, active site lid Rad50_zn_hook PF04423.14 AIN99979.1 - 1.9 8.4 3.6 9.1 6.2 0.1 2.5 2 0 0 2 2 2 0 Rad50 zinc hook motif YacG PF03884.14 AIN99979.1 - 3.7 7.4 6.8 2.1 8.1 1.4 2.4 2 0 0 2 2 2 0 DNA gyrase inhibitor YacG Prim_Zn_Ribbon PF08273.12 AIN99979.1 - 4.7 7.6 8.0 7 7.0 0.5 3.0 2 0 0 2 2 2 0 Zinc-binding domain of primase-helicase zinc_ribbon_2 PF13240.6 AIN99979.1 - 5.2 6.9 8.8 8.5 6.2 0.1 2.7 3 0 0 3 3 2 0 zinc-ribbon domain FHA PF00498.26 AIN99980.1 - 1.7e-06 28.3 0.0 2e-05 24.9 0.0 2.2 1 1 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 AIN99980.1 - 0.0074 16.6 0.0 3.2 8.1 0.0 2.3 2 0 0 2 2 2 2 Inner membrane component of T3SS, cytoplasmic domain STI1 PF17830.1 AIN99981.1 - 1.3e-11 44.2 13.3 1.3e-11 44.2 13.3 2.1 2 0 0 2 2 2 1 STI1 domain TPR_9 PF13371.6 AIN99981.1 - 7.7e-05 22.8 2.0 0.00011 22.3 0.3 2.2 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.28 AIN99981.1 - 0.0057 16.4 0.1 17 5.4 0.3 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.17 AIN99981.1 - 0.029 14.5 15.2 0.58 10.4 0.0 4.5 5 0 0 5 5 5 0 Tetratricopeptide repeat HTH_IclR PF09339.10 AIN99981.1 - 0.041 13.7 0.2 0.13 12.1 0.2 1.9 1 0 0 1 1 1 0 IclR helix-turn-helix domain TPR_11 PF13414.6 AIN99981.1 - 0.055 13.2 0.0 0.86 9.3 0.0 2.6 2 1 1 3 3 3 0 TPR repeat TPR_17 PF13431.6 AIN99981.1 - 0.057 13.8 0.2 6.1 7.5 0.1 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF2999 PF11212.8 AIN99981.1 - 0.063 13.6 5.1 19 5.6 0.0 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF2999) P_C10 PF14974.6 AIN99981.1 - 2.3 8.4 5.3 0.61 10.2 1.1 2.1 2 0 0 2 2 2 0 Protein C10 ArfGap PF01412.18 AIN99982.1 - 1.2e-37 128.6 0.1 1.2e-37 128.6 0.1 1.6 2 0 0 2 2 2 1 Putative GTPase activating protein for Arf KIAA1328 PF15369.6 AIN99982.1 - 0.19 11.5 5.5 0.52 10.1 2.9 2.2 2 0 0 2 2 2 0 Uncharacterised protein KIAA1328 Ribosomal_60s PF00428.19 AIN99982.1 - 5.5 7.7 10.2 10 6.8 2.1 3.0 3 0 0 3 3 3 0 60s Acidic ribosomal protein UBA_4 PF14555.6 AIN99983.1 - 1.5e-06 27.9 0.1 3.1e-06 26.9 0.1 1.5 1 0 0 1 1 1 1 UBA-like domain Thioredoxin_7 PF13899.6 AIN99983.1 - 0.0013 18.9 0.1 0.0042 17.2 0.0 1.9 2 0 0 2 2 2 1 Thioredoxin-like IQ PF00612.27 AIN99984.1 - 0.067 13.0 8.4 0.77 9.7 3.8 3.3 2 0 0 2 2 2 0 IQ calmodulin-binding motif DUF4549 PF15082.6 AIN99984.1 - 3.7 7.3 10.1 1.3 8.8 0.2 3.8 4 0 0 4 4 4 0 Domain of unknown function (DUF4549) zf-met PF12874.7 AIN99985.1 - 0.0019 18.5 0.4 0.0036 17.6 0.4 1.4 1 0 0 1 1 1 1 Zinc-finger of C2H2 type Pkinase PF00069.25 AIN99986.1 - 7.1e-41 140.3 0.0 4e-19 69.0 0.0 3.2 3 0 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.17 AIN99986.1 - 9.9e-21 74.2 0.0 5.2e-12 45.6 0.0 3.0 3 0 0 3 3 3 2 Protein tyrosine kinase Kinase-like PF14531.6 AIN99986.1 - 0.011 15.1 0.0 4.4 6.5 0.0 2.3 2 0 0 2 2 2 0 Kinase-like APH PF01636.23 AIN99986.1 - 0.032 14.2 0.9 0.15 12.0 0.3 2.1 1 1 0 2 2 2 0 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.11 AIN99986.1 - 0.044 12.8 0.0 0.066 12.2 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase C2-C2_1 PF11618.8 AIN99987.1 - 3.4e-07 30.4 5.0 3.1e-06 27.3 0.0 3.9 4 0 0 4 4 4 1 First C2 domain of RPGR-interacting protein 1 TraG_N PF07916.11 AIN99987.1 - 3.4 6.4 15.0 1.6 7.5 4.8 2.6 2 0 0 2 2 2 0 TraG-like protein, N-terminal region Fez1 PF06818.15 AIN99987.1 - 4.5 7.7 47.6 2.4 8.5 19.6 4.4 4 1 0 4 4 4 0 Fez1 COMM_domain PF07258.14 AIN99987.1 - 9.9 6.4 8.1 1.8 8.7 0.1 3.5 4 0 0 4 4 4 0 COMM domain RRM_1 PF00076.22 AIN99988.1 - 5.7e-15 54.9 0.1 1.3e-06 28.1 0.1 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 AIN99988.1 - 0.045 13.8 0.1 2.4 8.2 0.0 2.5 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif RNA_pol_Rpb4 PF03874.16 AIN99989.1 - 4.8e-05 23.7 0.0 6.2e-05 23.3 0.0 1.5 1 1 0 1 1 1 1 RNA polymerase Rpb4 Prolamin_like PF05617.11 AIN99989.1 - 0.045 13.9 0.0 0.066 13.4 0.0 1.3 1 0 0 1 1 1 0 Prolamin-like zf-CCCH PF00642.24 AIN99991.1 - 0.0078 16.1 0.4 0.012 15.5 0.4 1.3 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Torus PF16131.5 AIN99991.1 - 0.02 15.6 0.0 0.039 14.7 0.0 1.4 1 0 0 1 1 1 0 Torus domain zf_CCCH_4 PF18345.1 AIN99991.1 - 1 9.5 5.7 1.7 8.8 5.7 1.4 1 0 0 1 1 1 0 Zinc finger domain PPR_1 PF12854.7 AIN99992.1 - 0.03 14.0 0.1 0.17 11.6 0.0 2.1 2 0 0 2 2 2 0 PPR repeat PPR PF01535.20 AIN99992.1 - 0.031 14.5 0.0 24 5.4 0.0 3.7 3 0 0 3 3 3 0 PPR repeat PPR_2 PF13041.6 AIN99992.1 - 0.12 12.6 0.0 0.5 10.6 0.0 2.1 1 0 0 1 1 1 0 PPR repeat family HycH PF07450.11 AIN99992.1 - 0.13 12.7 0.0 1.6 9.1 0.0 2.4 2 0 0 2 2 2 0 Formate hydrogenlyase maturation protein HycH DUF2890 PF11081.8 AIN99992.1 - 0.24 11.5 1.7 0.46 10.6 1.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) Metallophos PF00149.28 AIN99993.1 - 2.9e-07 31.2 0.0 4.3e-07 30.6 0.0 1.3 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Rad51 PF08423.11 AIN99994.1 - 4.3e-18 65.5 0.2 1.6e-08 34.2 0.0 2.2 2 0 0 2 2 2 2 Rad51 RecA PF00154.21 AIN99994.1 - 8.5e-07 28.7 0.6 3.1e-06 26.8 0.0 1.9 2 0 0 2 2 2 1 recA bacterial DNA recombination protein ATPase PF06745.13 AIN99994.1 - 4.4e-06 26.2 0.0 7.4e-06 25.5 0.0 1.3 1 0 0 1 1 1 1 KaiC Phage_GP20 PF06810.11 AIN99995.1 - 0.096 12.5 12.5 0.025 14.4 4.1 2.7 2 0 0 2 2 2 0 Phage minor structural protein GP20 Gly-zipper_Omp PF13488.6 AIN99996.1 - 0.032 14.2 12.8 0.031 14.3 8.2 2.5 2 0 0 2 2 2 0 Glycine zipper Cofilin_ADF PF00241.20 AIO00001.1 - 4.2e-30 104.0 0.0 4.8e-30 103.9 0.0 1.0 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein RNase_T PF00929.24 AIO00004.1 - 8.9e-26 91.4 0.0 8.8e-24 84.9 0.0 2.2 1 1 0 1 1 1 1 Exonuclease RNase_T PF00929.24 AIO00005.1 - 5e-26 92.2 0.0 8e-26 91.5 0.0 1.3 1 0 0 1 1 1 1 Exonuclease DUF5051 PF16473.5 AIO00005.1 - 0.15 12.0 0.0 0.25 11.3 0.0 1.3 1 0 0 1 1 1 0 3' exoribonuclease, RNase T-like RNase_T PF00929.24 AIO00006.1 - 2e-27 96.8 0.0 3.2e-27 96.1 0.0 1.4 1 0 0 1 1 1 1 Exonuclease Ank_2 PF12796.7 AIO00007.1 - 1.3e-11 44.9 0.4 4.2e-07 30.5 0.4 2.5 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 AIO00007.1 - 3.3e-08 33.9 0.5 0.0034 17.9 0.1 3.1 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 AIO00007.1 - 3.4e-06 27.3 1.8 0.17 12.4 0.1 3.9 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.6 AIO00007.1 - 8.5e-06 25.7 1.2 3.5 8.5 0.0 4.0 3 0 0 3 3 3 3 Ankyrin repeat Ank_5 PF13857.6 AIO00007.1 - 0.0053 17.1 0.8 0.71 10.3 0.0 3.0 2 0 0 2 2 2 1 Ankyrin repeats (many copies) ERCC3_RAD25_C PF16203.5 AIO00009.1 - 2.5e-61 207.0 0.0 9.4e-54 182.2 0.0 2.2 2 0 0 2 2 2 2 ERCC3/RAD25/XPB C-terminal helicase ResIII PF04851.15 AIO00009.1 - 3.8e-14 53.0 0.0 5.9e-14 52.4 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 AIO00009.1 - 5.3e-10 39.6 0.0 1.4e-09 38.3 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Helicase_C_3 PF13625.6 AIO00009.1 - 1.8e-08 34.6 0.1 6.2e-08 32.8 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 AIO00009.1 - 0.019 14.7 0.0 0.034 13.9 0.0 1.4 1 0 0 1 1 1 0 DEAD/DEAH box helicase DUF3884 PF13024.6 AIO00009.1 - 0.22 11.1 0.5 0.46 10.1 0.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3884) zf-NF-X1 PF01422.17 AIO00010.1 - 2.5e-07 30.6 59.8 3e-05 24.0 18.5 14.3 13 0 0 13 13 13 6 NF-X1 type zinc finger zf-CCHC_2 PF13696.6 AIO00011.1 - 5.7e-08 32.4 4.3 1.1e-07 31.5 4.3 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-C2H2_jaz PF12171.8 AIO00011.1 - 0.0003 21.0 0.2 0.00084 19.6 0.2 1.8 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding Rubredoxin_2 PF18073.1 AIO00011.1 - 0.026 14.2 1.8 0.026 14.2 1.8 1.8 2 0 0 2 2 2 0 Rubredoxin metal binding domain zf-CCHC_5 PF14787.6 AIO00011.1 - 0.027 14.2 1.1 0.074 12.8 1.1 1.8 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger eIF3g PF12353.8 AIO00011.1 - 0.031 14.7 0.0 0.089 13.2 0.0 1.8 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit G NUFIP1 PF10453.9 AIO00011.1 - 0.04 13.8 0.0 0.1 12.5 0.0 1.6 1 0 0 1 1 1 0 Nuclear fragile X mental retardation-interacting protein 1 (NUFIP1) zf-C2H2_4 PF13894.6 AIO00011.1 - 0.071 14.0 0.1 0.071 14.0 0.1 3.3 2 1 1 3 3 3 0 C2H2-type zinc finger zf-LITAF-like PF10601.9 AIO00011.1 - 0.083 13.2 0.5 0.083 13.2 0.5 1.7 2 0 0 2 2 2 0 LITAF-like zinc ribbon domain zf-met PF12874.7 AIO00011.1 - 0.15 12.5 0.2 0.42 11.1 0.2 1.9 1 0 0 1 1 1 0 Zinc-finger of C2H2 type zf-C2H2 PF00096.26 AIO00011.1 - 0.28 11.7 0.1 0.28 11.7 0.1 3.4 3 0 0 3 3 3 0 Zinc finger, C2H2 type ABC2_membrane_3 PF12698.7 AIO00012.1 - 7.7e-61 206.1 53.2 3.8e-44 151.2 23.9 3.1 3 0 0 3 3 3 2 ABC-2 family transporter protein ABC_tran PF00005.27 AIO00012.1 - 2.6e-57 193.2 0.0 3e-27 95.8 0.0 2.3 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 AIO00012.1 - 6.2e-11 42.6 6.6 0.00079 19.3 0.0 4.3 3 1 0 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 AIO00012.1 - 5.5e-09 35.8 1.3 0.00013 21.4 0.0 3.4 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 AIO00012.1 - 3.8e-05 23.4 1.8 0.0057 16.4 0.2 2.7 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_30 PF13604.6 AIO00012.1 - 0.0011 18.7 0.3 0.15 11.7 0.1 2.3 2 0 0 2 2 2 1 AAA domain AAA_23 PF13476.6 AIO00012.1 - 0.0018 18.8 0.7 0.21 12.1 0.0 2.2 2 0 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 AIO00012.1 - 0.0019 18.2 1.1 0.95 9.3 0.1 2.4 2 0 0 2 2 2 2 RsgA GTPase DUF3694 PF12473.8 AIO00012.1 - 0.0042 17.8 0.2 0.54 10.9 0.1 2.5 2 0 0 2 2 2 1 Kinesin protein Arf PF00025.21 AIO00012.1 - 0.05 13.0 0.1 0.44 10.0 0.0 2.2 2 0 0 2 2 2 0 ADP-ribosylation factor family AAA_25 PF13481.6 AIO00012.1 - 0.069 12.7 0.5 12 5.4 0.1 2.7 2 0 0 2 2 2 0 AAA domain SbcCD_C PF13558.6 AIO00012.1 - 0.12 12.6 0.1 6.4 7.1 0.1 3.1 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_27 PF13514.6 AIO00012.1 - 0.28 10.8 0.3 1.1 8.8 0.0 1.9 2 0 0 2 2 2 0 AAA domain SRP54 PF00448.22 AIO00012.1 - 0.4 10.3 2.6 2.8 7.5 0.3 2.2 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_18 PF13238.6 AIO00012.1 - 0.47 11.0 1.2 11 6.6 0.0 3.1 3 0 0 3 3 3 0 AAA domain ERM PF00769.19 AIO00013.1 - 0.034 14.0 0.7 0.044 13.6 0.7 1.1 1 0 0 1 1 1 0 Ezrin/radixin/moesin family DUF2207 PF09972.9 AIO00013.1 - 0.095 11.5 0.0 0.11 11.3 0.0 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DcpS_C PF11969.8 AIO00014.1 - 6.7e-23 81.3 0.6 1.5e-22 80.2 0.6 1.5 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding HIT PF01230.23 AIO00014.1 - 3.1e-13 50.3 0.1 1e-12 48.6 0.1 1.8 2 0 0 2 2 2 1 HIT domain zf-C2HE PF16278.5 AIO00014.1 - 4.4e-09 36.7 0.0 8.2e-09 35.8 0.0 1.5 1 0 0 1 1 1 1 C2HE / C2H2 / C2HC zinc-binding finger PHO4 PF01384.20 AIO00015.1 - 3.4e-83 279.5 18.3 4.2e-83 279.2 18.3 1.1 1 0 0 1 1 1 1 Phosphate transporter family DUF436 PF04260.12 AIO00015.1 - 0.056 13.0 0.3 0.14 11.7 0.3 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF436) Radial_spoke PF04712.12 AIO00016.1 - 1e-119 400.7 0.0 1.6e-119 400.1 0.0 1.2 1 0 0 1 1 1 1 Radial spokehead-like protein RRM_1 PF00076.22 AIO00018.1 - 2.3e-22 78.6 0.0 1e-13 50.9 0.0 3.5 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 AIO00018.1 - 0.011 15.5 0.0 2.4 8.1 0.0 3.1 3 0 0 3 3 3 0 Occluded RNA-recognition motif RHD3 PF05879.12 AIO00019.1 - 0.0048 15.1 0.0 0.0063 14.7 0.0 1.0 1 0 0 1 1 1 1 Root hair defective 3 GTP-binding protein (RHD3) CLAMP PF14769.6 AIO00020.1 - 0.00095 19.6 0.0 0.029 14.8 0.0 2.6 2 0 0 2 2 2 1 Flagellar C1a complex subunit C1a-32 BBS2_Mid PF14783.6 AIO00021.1 - 0.0013 18.8 0.1 1.9 8.6 0.0 2.9 3 0 0 3 3 3 2 Ciliary BBSome complex subunit 2, middle region FG-GAP PF01839.23 AIO00021.1 - 0.0043 17.1 2.7 0.0043 17.1 2.7 1.9 2 0 0 2 2 2 1 FG-GAP repeat VCBS PF13517.6 AIO00021.1 - 0.016 15.8 0.1 0.053 14.1 0.0 2.0 2 0 0 2 2 2 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella BBS2_C PF14782.6 AIO00021.1 - 0.13 11.0 0.8 12 4.5 0.0 2.9 3 0 0 3 3 3 0 Ciliary BBSome complex subunit 2, C-terminal YdfA_immunity PF12127.8 AIO00021.1 - 3.9 6.4 8.1 0.079 12.0 0.8 1.8 2 0 0 2 2 2 0 SigmaW regulon antibacterial EF_TS PF00889.19 AIO00022.1 - 3e-13 49.9 0.0 8.2e-13 48.4 0.0 1.6 1 1 1 2 2 2 1 Elongation factor TS WD40 PF00400.32 AIO00024.1 - 5.1e-17 61.9 10.1 0.00045 21.0 0.0 5.9 6 0 0 6 6 6 5 WD domain, G-beta repeat Neocarzinostat PF00960.18 AIO00024.1 - 0.064 13.2 0.4 0.13 12.3 0.4 1.5 1 0 0 1 1 1 0 Neocarzinostatin family Mpp10 PF04006.12 AIO00025.1 - 1.8e-63 215.0 34.7 4.2e-63 213.8 34.7 1.6 1 1 0 1 1 1 1 Mpp10 protein HSP90 PF00183.18 AIO00026.1 - 2.4e-171 571.2 5.2 3.1e-171 570.8 5.2 1.1 1 0 0 1 1 1 1 Hsp90 protein HATPase_c_3 PF13589.6 AIO00026.1 - 1.4e-07 31.4 0.0 3.8e-07 30.0 0.0 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 AIO00026.1 - 3.4e-07 30.8 0.0 1e-06 29.2 0.0 1.9 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase GSH-S_ATP PF02955.16 AIO00026.1 - 0.025 14.0 0.0 1.1 8.6 0.0 2.4 2 0 0 2 2 2 0 Prokaryotic glutathione synthetase, ATP-grasp domain Coilin_N PF15862.5 AIO00026.1 - 0.098 12.5 0.1 0.85 9.4 0.0 2.4 3 0 0 3 3 3 0 Coilin N-terminus Plasmid_RAQPRD PF09686.10 AIO00027.1 - 0.057 13.6 5.2 2.1 8.6 0.3 2.4 2 0 0 2 2 2 0 Plasmid protein of unknown function (Plasmid_RAQPRD) U-box PF04564.15 AIO00028.1 - 3.2e-12 46.4 0.0 3.7e-11 43.0 0.0 2.7 3 0 0 3 3 3 1 U-box domain zf-Nse PF11789.8 AIO00028.1 - 0.00083 19.1 0.0 0.0023 17.7 0.0 1.7 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit YjbT PF17089.5 AIO00028.1 - 0.019 15.0 0.8 1.8 8.7 0.0 3.1 2 1 1 3 3 3 0 Uncharacterised protein family PET117 PF15786.5 AIO00029.1 - 0.065 13.5 0.3 1.8 8.9 0.1 3.0 2 0 0 2 2 2 0 PET assembly of cytochrome c oxidase, mitochondrial Peptidase_C1 PF00112.23 AIO00033.1 - 1.7e-60 204.8 3.0 2e-60 204.6 3.0 1.1 1 0 0 1 1 1 1 Papain family cysteine protease Peptidase_C1_2 PF03051.15 AIO00033.1 - 3.6e-05 22.7 0.6 0.0029 16.4 0.2 2.1 2 0 0 2 2 2 2 Peptidase C1-like family Propeptide_C1 PF08127.13 AIO00033.1 - 0.0059 16.5 0.1 0.012 15.5 0.1 1.5 1 0 0 1 1 1 1 Peptidase family C1 propeptide RecO_N_2 PF13114.6 AIO00033.1 - 0.092 12.5 0.0 0.21 11.3 0.0 1.5 1 0 0 1 1 1 0 RecO N terminal Nop14 PF04147.12 AIO00034.1 - 0.87 7.7 4.1 1.1 7.4 4.1 1.1 1 0 0 1 1 1 0 Nop14-like family FoP_duplication PF13865.6 AIO00034.1 - 1.9 9.1 10.8 4.2 8.0 10.8 1.5 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 DUF1634 PF07843.11 AIO00035.1 - 4.9 7.3 9.4 5 7.3 0.3 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF1634) DUF4079 PF13301.6 AIO00035.1 - 6.9 6.8 7.5 2.8 8.1 1.3 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF4079) HMG_box PF00505.19 AIO00036.1 - 4.7e-30 103.8 18.9 1.6e-20 73.2 1.1 3.1 3 0 0 3 3 3 2 HMG (high mobility group) box HMG_box_2 PF09011.10 AIO00036.1 - 7e-20 71.4 20.5 2.9e-12 47.0 1.2 3.2 2 1 1 3 3 3 2 HMG-box domain Protamine_like PF06382.11 AIO00036.1 - 5.9e-08 33.0 13.1 0.0001 22.5 1.9 2.2 1 1 1 2 2 2 2 Protamine and protamine like DEK_C PF08766.11 AIO00036.1 - 5.9e-06 26.1 0.0 1.2e-05 25.2 0.0 1.5 1 0 0 1 1 1 1 DEK C terminal domain COX4 PF02936.14 AIO00036.1 - 0.0046 17.0 3.2 0.77 9.8 0.5 2.5 2 0 0 2 2 2 2 Cytochrome c oxidase subunit IV HMG_box_5 PF14887.6 AIO00036.1 - 0.0089 16.0 16.5 0.013 15.4 1.1 2.9 3 0 0 3 3 3 2 HMG (high mobility group) box 5 YABBY PF04690.13 AIO00036.1 - 0.013 16.0 4.5 0.013 16.0 4.5 1.8 1 1 1 2 2 2 0 YABBY protein DUF2582 PF10771.9 AIO00036.1 - 0.057 13.6 0.9 2.2 8.5 0.1 2.5 2 0 0 2 2 2 0 Winged helix-turn-helix domain (DUF2582) Mon1 PF03164.14 AIO00036.1 - 0.084 11.9 0.0 0.12 11.4 0.0 1.2 1 0 0 1 1 1 0 Trafficking protein Mon1 DUF538 PF04398.12 AIO00036.1 - 0.11 12.9 0.0 0.73 10.3 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function, DUF538 WRNPLPNID PF15017.6 AIO00036.1 - 0.16 12.8 0.6 0.16 12.8 0.6 2.6 3 0 0 3 3 3 0 Putative WW-binding domain and destruction box RRM_1 PF00076.22 AIO00038.1 - 5.6e-07 29.3 0.0 8.4e-07 28.7 0.0 1.3 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 AIO00038.1 - 0.033 13.8 0.0 0.037 13.6 0.0 1.1 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 AIO00038.1 - 0.12 12.3 0.0 0.17 11.7 0.0 1.2 1 0 0 1 1 1 0 Occluded RNA-recognition motif Amidohydro_1 PF01979.20 AIO00039.1 - 2.3e-56 191.6 0.0 4e-56 190.8 0.0 1.4 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 AIO00039.1 - 7.4e-10 38.9 0.0 4.4e-06 26.4 0.0 2.3 2 0 0 2 2 2 2 Amidohydrolase family Cyt-b5 PF00173.28 AIO00040.1 - 8.5e-09 35.4 0.0 1.3e-08 34.8 0.0 1.3 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain DUF4932 PF16286.5 AIO00041.1 - 0.052 12.8 0.0 0.091 12.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4932) TPR_19 PF14559.6 AIO00041.1 - 0.83 10.2 4.2 7.1 7.2 0.0 3.4 3 1 1 4 4 4 0 Tetratricopeptide repeat Arf PF00025.21 AIO00042.1 - 5.9e-64 214.7 0.0 6.6e-64 214.6 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 AIO00042.1 - 1.4e-14 54.4 0.0 1.9e-14 53.9 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 AIO00042.1 - 1.5e-14 53.9 0.0 1.8e-14 53.6 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.22 AIO00042.1 - 1.9e-14 53.6 0.0 2.2e-14 53.4 0.0 1.0 1 0 0 1 1 1 1 Ras family G-alpha PF00503.20 AIO00042.1 - 3.8e-12 46.1 0.0 4.8e-09 35.8 0.0 2.4 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.12 AIO00042.1 - 1.1e-10 41.2 0.0 1.4e-10 41.0 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 AIO00042.1 - 2.7e-08 33.9 0.0 3.9e-08 33.4 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase TniB PF05621.11 AIO00042.1 - 0.0049 16.3 0.0 0.0081 15.6 0.0 1.3 1 0 0 1 1 1 1 Bacterial TniB protein cobW PF02492.19 AIO00042.1 - 0.0074 15.9 0.0 0.11 12.1 0.0 2.0 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain RsgA_GTPase PF03193.16 AIO00042.1 - 0.059 13.3 0.0 11 5.9 0.0 2.2 2 0 0 2 2 2 0 RsgA GTPase AAA_16 PF13191.6 AIO00042.1 - 0.12 12.7 0.1 0.24 11.8 0.1 1.6 1 1 0 1 1 1 0 AAA ATPase domain C1_1 PF00130.22 AIO00043.1 - 0.00049 19.9 6.9 0.00049 19.9 6.9 1.8 1 1 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) PhyH PF05721.13 AIO00043.1 - 0.0021 18.3 0.0 0.0079 16.5 0.0 2.2 2 1 0 2 2 2 1 Phytanoyl-CoA dioxygenase (PhyH) PHD PF00628.29 AIO00043.1 - 0.0082 16.0 10.1 0.017 15.0 10.1 1.6 1 0 0 1 1 1 1 PHD-finger Prok-RING_1 PF14446.6 AIO00043.1 - 0.66 10.0 11.1 1.7 8.6 11.1 1.7 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 PHD_4 PF16866.5 AIO00043.1 - 1.7 8.8 8.7 4 7.6 8.7 1.7 1 0 0 1 1 1 0 PHD-finger OrfB_Zn_ribbon PF07282.11 AIO00043.1 - 3.2 7.8 9.1 0.26 11.2 3.5 2.0 2 0 0 2 2 2 0 Putative transposase DNA-binding domain SLC35F PF06027.12 AIO00044.1 - 1.1e-62 212.2 28.5 2.5e-47 161.9 7.8 2.0 2 0 0 2 2 2 2 Solute carrier family 35 CRT-like PF08627.10 AIO00044.1 - 1.7e-13 50.3 7.2 1.7e-13 50.3 7.2 2.0 2 1 0 2 2 2 1 CRT-like, chloroquine-resistance transporter-like EamA PF00892.20 AIO00044.1 - 7.6e-10 39.1 43.4 0.00014 22.0 13.8 3.2 3 0 0 3 3 3 3 EamA-like transporter family IPPT PF01715.17 AIO00045.1 - 2.3e-15 57.0 0.0 4.2e-15 56.2 0.0 1.4 1 0 0 1 1 1 1 IPP transferase zf-met PF12874.7 AIO00045.1 - 3.9e-07 30.2 0.3 7.4e-07 29.4 0.3 1.4 1 0 0 1 1 1 1 Zinc-finger of C2H2 type DUF3449 PF11931.8 AIO00045.1 - 0.011 15.5 0.0 0.013 15.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3449) AKAP95 PF04988.12 AIO00045.1 - 0.013 15.8 0.1 0.023 14.9 0.1 1.3 1 0 0 1 1 1 0 A-kinase anchoring protein 95 (AKAP95) zf-C2H2_jaz PF12171.8 AIO00045.1 - 0.032 14.5 0.1 0.066 13.5 0.1 1.5 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding DUF829 PF05705.14 AIO00045.1 - 0.13 12.2 0.0 3.7 7.4 0.0 2.1 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF829) Peptidase_A22B PF04258.13 AIO00046.1 - 1.3e-60 205.4 18.1 2.6e-55 188.0 11.3 2.0 1 1 1 2 2 2 2 Signal peptide peptidase LETM1 PF07766.13 AIO00047.1 - 1.2e-61 208.4 0.0 5.8e-61 206.2 0.0 1.9 2 0 0 2 2 2 1 LETM1-like protein DASH_Duo1 PF08651.10 AIO00047.1 - 0.061 13.1 0.1 0.14 11.9 0.1 1.5 1 0 0 1 1 1 0 DASH complex subunit Duo1 FGE-sulfatase PF03781.16 AIO00050.1 - 3.2e-20 72.8 0.4 7e-20 71.7 0.4 1.6 1 1 0 1 1 1 1 Sulfatase-modifying factor enzyme 1 Methyltransf_25 PF13649.6 AIO00050.1 - 4e-07 30.6 0.1 4.1e-05 24.2 0.1 2.6 1 1 0 1 1 1 1 Methyltransferase domain DinB_2 PF12867.7 AIO00050.1 - 3.6e-06 27.5 0.0 8.9e-06 26.2 0.0 1.8 1 0 0 1 1 1 1 DinB superfamily Methyltransf_31 PF13847.6 AIO00050.1 - 0.00018 21.4 0.0 0.014 15.2 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 AIO00050.1 - 0.0014 19.2 0.0 0.015 16.0 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 AIO00050.1 - 0.0091 15.8 0.0 0.026 14.4 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 AIO00050.1 - 0.011 16.4 0.0 0.034 14.9 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase domain DUF2938 PF11158.8 AIO00051.1 - 0.047 13.2 0.0 0.08 12.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2938) DUF2206 PF09971.9 AIO00051.1 - 0.28 9.9 0.9 0.41 9.4 0.9 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2206) Kinesin PF00225.23 AIO00053.1 - 3e-83 279.5 0.0 3e-83 279.5 0.0 3.1 2 1 1 3 3 3 1 Kinesin motor domain Microtub_bd PF16796.5 AIO00053.1 - 2.7e-15 56.6 0.0 1.8e-14 53.9 0.0 2.6 1 0 0 1 1 1 1 Microtubule binding GREB1 PF15782.5 AIO00055.1 - 1.4 5.9 4.8 2.5 5.1 4.8 1.2 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Baculo_PEP_C PF04513.12 AIO00056.1 - 0.00016 21.7 1.5 1.1 9.3 0.7 3.1 3 0 0 3 3 3 2 Baculovirus polyhedron envelope protein, PEP, C terminus CCDC106 PF15794.5 AIO00056.1 - 0.00024 20.9 2.0 0.14 11.8 2.2 2.7 2 0 0 2 2 2 1 Coiled-coil domain-containing protein 106 Mto2_bdg PF12808.7 AIO00056.1 - 0.0025 18.1 6.9 0.069 13.4 0.2 3.6 3 0 0 3 3 2 1 Micro-tubular organiser Mto1 C-term Mto2-binding region EzrA PF06160.12 AIO00056.1 - 0.0056 14.9 0.8 0.11 10.7 1.2 2.4 2 1 0 2 2 2 1 Septation ring formation regulator, EzrA DUF4795 PF16043.5 AIO00056.1 - 0.007 16.0 4.6 0.007 16.0 4.6 3.0 2 1 0 3 3 3 1 Domain of unknown function (DUF4795) TMF_TATA_bd PF12325.8 AIO00056.1 - 0.02 15.1 12.8 0.052 13.8 1.7 3.2 3 0 0 3 3 3 0 TATA element modulatory factor 1 TATA binding YabA PF06156.13 AIO00056.1 - 0.027 15.1 10.6 0.033 14.8 1.7 4.1 3 2 0 3 3 3 0 Initiation control protein YabA Qua1 PF16274.5 AIO00056.1 - 0.12 12.2 0.0 0.4 10.6 0.0 1.9 1 0 0 1 1 1 0 Qua1 domain Tropomyosin_1 PF12718.7 AIO00056.1 - 0.14 12.3 16.8 4.3 7.5 0.2 4.1 3 1 1 4 4 4 0 Tropomyosin like SKA1 PF07160.12 AIO00056.1 - 0.19 11.6 12.3 4.2 7.1 3.3 3.3 3 0 0 3 3 3 0 Spindle and kinetochore-associated protein 1 Arfaptin PF06456.13 AIO00056.1 - 0.19 11.3 7.1 0.13 11.9 1.3 2.5 2 0 0 2 2 2 0 Arfaptin-like domain Phage_GP20 PF06810.11 AIO00056.1 - 0.21 11.4 9.6 0.36 10.6 4.5 2.8 3 0 0 3 3 3 0 Phage minor structural protein GP20 CLZ PF16526.5 AIO00056.1 - 0.29 11.5 8.8 7.2 7.1 0.0 5.1 4 2 2 6 6 5 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels bZIP_1 PF00170.21 AIO00056.1 - 0.64 10.2 5.3 2.1 8.5 0.1 3.6 2 1 1 3 3 3 0 bZIP transcription factor DUF5446 PF17522.2 AIO00056.1 - 0.64 10.2 0.1 0.64 10.2 0.1 3.6 4 0 0 4 4 4 0 Family of unknown function (DUF5446) DUF948 PF06103.11 AIO00056.1 - 0.81 10.0 3.3 10 6.5 1.2 3.0 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Spc7 PF08317.11 AIO00056.1 - 1.2 7.9 20.3 0.024 13.5 5.1 3.1 3 0 0 3 3 3 0 Spc7 kinetochore protein Exonuc_VII_L PF02601.15 AIO00056.1 - 1.3 8.5 17.3 0.47 10.0 4.6 3.1 2 1 1 3 3 3 0 Exonuclease VII, large subunit ZapB PF06005.12 AIO00056.1 - 1.9 9.0 19.4 0.31 11.5 2.1 3.9 3 1 0 3 3 3 0 Cell division protein ZapB TSC22 PF01166.18 AIO00056.1 - 2.3 8.6 13.1 4.3 7.7 0.0 5.3 6 1 0 6 6 5 0 TSC-22/dip/bun family BLOC1_2 PF10046.9 AIO00056.1 - 3.7 7.9 8.3 0.48 10.7 0.5 3.1 3 1 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 bZIP_2 PF07716.15 AIO00056.1 - 3.8 7.7 11.2 0.8 9.8 0.2 4.6 5 0 0 5 5 5 0 Basic region leucine zipper AATF-Che1 PF13339.6 AIO00056.1 - 4 8.1 12.8 23 5.7 4.5 3.8 3 2 1 4 4 4 0 Apoptosis antagonizing transcription factor LPP PF04728.13 AIO00056.1 - 5.1 7.6 9.3 2.1 8.8 1.3 4.1 4 0 0 4 4 4 0 Lipoprotein leucine-zipper Fib_alpha PF08702.10 AIO00056.1 - 7 6.8 12.0 0.83 9.8 0.6 3.8 3 2 2 5 5 5 0 Fibrinogen alpha/beta chain family FAM76 PF16046.5 AIO00056.1 - 8.1 5.7 7.2 1.6 8.0 2.9 2.0 2 0 0 2 2 2 0 FAM76 protein ADH_zinc_N_2 PF13602.6 AIO00057.1 - 6.2e-16 59.7 0.0 1.7e-15 58.2 0.0 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 AIO00057.1 - 6.9e-11 42.0 2.6 2.4e-10 40.3 0.1 2.4 2 1 1 3 3 3 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 AIO00057.1 - 7.8e-08 32.4 0.1 5e-07 29.8 0.0 2.1 2 0 0 2 2 2 1 Zinc-binding dehydrogenase SseB PF07179.12 AIO00058.1 - 0.004 17.4 0.0 3.1 8.1 0.0 2.6 2 0 0 2 2 2 2 SseB protein N-terminal domain CorA PF01544.18 AIO00059.1 - 0.93 8.8 4.2 1.2 8.3 4.2 1.3 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein MCM3AP_GANP PF16769.5 AIO00059.1 - 1 7.5 7.3 1.2 7.4 7.3 1.2 1 0 0 1 1 1 0 MCM3AP domain of GANP cNMP_binding PF00027.29 AIO00060.1 - 8.4e-14 51.4 0.0 2.1e-07 30.9 0.0 4.9 5 0 0 5 5 5 4 Cyclic nucleotide-binding domain Ku PF02735.16 AIO00061.1 - 2.8e-24 85.9 0.0 5.6e-24 85.0 0.0 1.4 1 0 0 1 1 1 1 Ku70/Ku80 beta-barrel domain Ku_N PF03731.15 AIO00061.1 - 6e-16 58.8 0.0 5.4e-10 39.4 0.0 2.5 3 0 0 3 3 3 2 Ku70/Ku80 N-terminal alpha/beta domain Ku_C PF03730.14 AIO00061.1 - 0.00053 20.6 0.0 0.11 13.3 0.2 2.6 2 0 0 2 2 2 1 Ku70/Ku80 C-terminal arm HeH PF12949.7 AIO00061.1 - 0.0063 16.2 0.0 0.015 15.0 0.0 1.7 1 0 0 1 1 1 1 HeH/LEM domain SAP PF02037.27 AIO00061.1 - 0.17 11.7 0.0 0.42 10.4 0.0 1.7 1 0 0 1 1 1 0 SAP domain Ribosomal_L4 PF00573.22 AIO00063.1 - 2.1e-35 122.2 0.1 3.2e-35 121.6 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family Ribos_L4_asso_C PF14374.6 AIO00063.1 - 7.4e-20 70.8 4.9 1.4e-19 69.9 2.4 2.3 2 0 0 2 2 2 1 60S ribosomal protein L4 C-terminal domain Ank_2 PF12796.7 AIO00064.1 - 8.9e-26 90.3 0.1 2e-07 31.5 0.0 4.3 2 1 2 4 4 4 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 AIO00064.1 - 2.9e-23 81.9 0.4 3e-10 40.4 0.0 4.8 4 1 1 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 AIO00064.1 - 4.8e-22 75.7 0.8 0.024 15.1 0.0 7.0 7 0 0 7 7 7 6 Ankyrin repeat Ank_5 PF13857.6 AIO00064.1 - 3.4e-18 65.5 0.5 5.5e-06 26.6 0.0 5.5 2 2 4 6 6 6 6 Ankyrin repeats (many copies) Ank PF00023.30 AIO00064.1 - 1.6e-16 59.9 0.7 0.0015 18.9 0.0 6.8 8 0 0 8 8 8 3 Ankyrin repeat B12-binding_2 PF02607.17 AIO00064.1 - 0.067 13.6 1.1 4.8 7.7 0.0 3.3 4 0 0 4 4 4 0 B12 binding domain PSP1 PF04468.12 AIO00066.1 - 6.5e-16 58.4 0.1 1.1e-15 57.6 0.1 1.4 1 0 0 1 1 1 1 PSP1 C-terminal conserved region Thioredoxin_8 PF13905.6 AIO00067.1 - 2.6e-10 40.5 0.0 4.6e-10 39.7 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin-like Redoxin PF08534.10 AIO00067.1 - 0.1 12.3 0.0 0.17 11.6 0.0 1.3 1 0 0 1 1 1 0 Redoxin Thioredoxin_8 PF13905.6 AIO00068.1 - 2e-20 72.9 0.0 5.7e-16 58.6 0.0 2.3 2 0 0 2 2 2 2 Thioredoxin-like AhpC-TSA PF00578.21 AIO00068.1 - 4.7e-12 45.9 0.0 8.7e-12 45.0 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 AIO00068.1 - 7.2e-12 45.2 0.0 1.7e-11 44.0 0.0 1.5 2 0 0 2 2 2 1 Redoxin Thioredoxin PF00085.20 AIO00068.1 - 2.7e-07 30.5 0.0 6.3e-07 29.3 0.0 1.7 2 0 0 2 2 2 1 Thioredoxin TraF PF13728.6 AIO00068.1 - 1.3e-05 25.1 0.0 3.1e-05 23.9 0.0 1.6 2 0 0 2 2 2 1 F plasmid transfer operon protein Thioredoxin_7 PF13899.6 AIO00068.1 - 0.00022 21.3 0.0 0.00048 20.3 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_2 PF13098.6 AIO00068.1 - 0.00053 20.4 0.0 0.0023 18.4 0.0 1.9 2 0 0 2 2 2 1 Thioredoxin-like domain Thioredoxin_9 PF14595.6 AIO00068.1 - 0.019 14.7 0.0 0.041 13.7 0.0 1.5 2 0 0 2 2 2 0 Thioredoxin Hex_IIIa PF02455.16 AIO00068.1 - 0.2 10.4 0.1 0.26 10.0 0.1 1.1 1 0 0 1 1 1 0 Hexon-associated protein (IIIa) Thioredoxin_8 PF13905.6 AIO00069.1 - 3.9e-22 78.4 0.0 5.1e-22 78.0 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin-like AhpC-TSA PF00578.21 AIO00069.1 - 4e-07 30.0 0.0 4.6e-07 29.8 0.0 1.3 1 1 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 AIO00069.1 - 1.7e-06 27.8 0.0 1.8e-06 27.7 0.0 1.1 1 0 0 1 1 1 1 Redoxin Thioredoxin PF00085.20 AIO00069.1 - 3.1e-06 27.1 0.2 2.9e-05 24.0 0.1 2.0 1 1 1 2 2 2 1 Thioredoxin TraF PF13728.6 AIO00069.1 - 9.2e-05 22.4 0.0 0.00035 20.5 0.0 1.8 1 1 0 1 1 1 1 F plasmid transfer operon protein Thioredoxin_2 PF13098.6 AIO00069.1 - 0.0002 21.8 0.0 0.00038 20.9 0.0 1.4 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_7 PF13899.6 AIO00069.1 - 0.014 15.6 0.0 0.022 14.9 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin-like DUF953 PF06110.11 AIO00069.1 - 0.019 14.5 0.3 0.5 10.0 0.3 2.1 1 1 0 1 1 1 0 Eukaryotic protein of unknown function (DUF953) Thioredoxin_9 PF14595.6 AIO00069.1 - 0.06 13.1 0.0 0.7 9.7 0.0 2.0 1 1 0 1 1 1 0 Thioredoxin Thioredoxin_8 PF13905.6 AIO00070.1 - 5.7e-23 81.1 0.0 8.2e-23 80.6 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin-like Redoxin PF08534.10 AIO00070.1 - 6e-09 35.8 0.1 9.6e-09 35.1 0.0 1.2 1 1 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 AIO00070.1 - 8.5e-09 35.4 0.0 1.4e-08 34.7 0.0 1.4 2 0 0 2 2 2 1 AhpC/TSA family Thioredoxin PF00085.20 AIO00070.1 - 2.4e-08 33.9 0.0 1.6e-07 31.2 0.0 1.9 1 1 0 2 2 2 1 Thioredoxin TraF PF13728.6 AIO00070.1 - 2e-05 24.6 0.0 5.9e-05 23.0 0.0 1.7 1 1 0 1 1 1 1 F plasmid transfer operon protein Thioredoxin_2 PF13098.6 AIO00070.1 - 0.001 19.5 0.0 0.0016 18.9 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_7 PF13899.6 AIO00070.1 - 0.0057 16.8 0.0 0.011 15.9 0.0 1.5 1 1 0 1 1 1 1 Thioredoxin-like Thioredoxin_9 PF14595.6 AIO00070.1 - 0.031 14.1 0.0 0.062 13.1 0.0 1.6 1 1 0 1 1 1 0 Thioredoxin Thioredoxin_8 PF13905.6 AIO00071.1 - 5.7e-23 81.1 0.0 8.2e-23 80.6 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin-like Redoxin PF08534.10 AIO00071.1 - 6.2e-09 35.7 0.1 6.8e-09 35.6 0.1 1.2 1 1 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 AIO00071.1 - 9.3e-09 35.3 0.0 1.4e-08 34.7 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin PF00085.20 AIO00071.1 - 2.1e-08 34.1 0.0 1.6e-07 31.2 0.0 1.9 1 1 0 2 2 2 1 Thioredoxin TraF PF13728.6 AIO00071.1 - 1.2e-05 25.2 0.0 5e-05 23.2 0.0 1.7 1 1 0 1 1 1 1 F plasmid transfer operon protein Thioredoxin_2 PF13098.6 AIO00071.1 - 0.00081 19.8 0.0 0.0013 19.2 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_7 PF13899.6 AIO00071.1 - 0.0059 16.8 0.0 0.011 15.9 0.0 1.5 1 1 0 1 1 1 1 Thioredoxin-like Thioredoxin_9 PF14595.6 AIO00071.1 - 0.021 14.6 0.0 0.058 13.2 0.0 1.8 1 1 0 1 1 1 0 Thioredoxin EF-hand_7 PF13499.6 AIO00072.1 - 3.3e-05 24.3 0.0 0.00012 22.4 0.0 1.9 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.32 AIO00072.1 - 9.8e-05 21.6 0.0 0.00019 20.8 0.0 1.5 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.6 AIO00072.1 - 0.0023 17.7 0.0 0.0055 16.6 0.0 1.7 1 0 0 1 1 1 1 EF-hand domain G-gamma PF00631.22 AIO00072.1 - 0.043 13.8 0.1 0.35 10.9 0.0 2.1 2 0 0 2 2 2 0 GGL domain SPT16 PF08644.11 AIO00072.1 - 0.059 13.5 0.0 0.12 12.5 0.0 1.5 1 0 0 1 1 1 0 FACT complex subunit (SPT16/CDC68) EF-hand_8 PF13833.6 AIO00072.1 - 0.096 12.6 0.0 0.24 11.3 0.0 1.6 1 0 0 1 1 1 0 EF-hand domain pair Thioredoxin_8 PF13905.6 AIO00073.1 - 8.5e-07 29.2 0.0 0.12 12.7 0.0 3.4 3 0 0 3 3 3 3 Thioredoxin-like Fijivirus_P9-2 PF06837.11 AIO00075.1 - 0.14 11.6 0.0 0.28 10.6 0.0 1.4 1 0 0 1 1 1 0 Fijivirus P9-2 protein DPM3 PF08285.11 AIO00075.1 - 1.5 9.1 9.8 0.11 12.7 4.1 2.1 2 0 0 2 2 2 0 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) DUF572 PF04502.13 AIO00077.1 - 5.6e-19 68.9 9.2 1.3e-18 67.8 9.3 1.4 1 1 0 1 1 1 1 Family of unknown function (DUF572) Sec16_C PF12931.7 AIO00078.1 - 2.8e-14 53.5 0.0 4.3e-14 52.9 0.0 1.2 1 0 0 1 1 1 1 Sec23-binding domain of Sec16 HSP70 PF00012.20 AIO00079.1 - 1.3e-24 86.3 8.4 3.9e-24 84.8 0.1 2.5 1 1 1 2 2 2 2 Hsp70 protein TPR_1 PF00515.28 AIO00079.1 - 5.2e-10 38.7 0.2 7.7e-06 25.5 0.2 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.17 AIO00079.1 - 1.1e-09 37.6 0.9 0.0001 22.1 0.3 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 AIO00079.1 - 1.6e-07 31.5 0.4 2.7e-05 24.4 0.0 3.0 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.6 AIO00079.1 - 8.4e-07 28.7 0.1 0.00056 19.9 0.2 3.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.6 AIO00079.1 - 6e-06 25.9 0.0 0.23 11.6 0.0 3.3 3 0 0 3 3 2 2 Tetratricopeptide repeat TPR_16 PF13432.6 AIO00079.1 - 1.8e-05 25.3 0.4 0.00022 21.8 0.1 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_9 PF13371.6 AIO00079.1 - 1.9e-05 24.7 2.0 8.7e-05 22.6 0.0 2.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.6 AIO00079.1 - 0.00035 21.0 0.2 0.0075 16.8 0.1 2.9 1 1 1 2 2 2 1 Tetratricopeptide repeat ANAPC3 PF12895.7 AIO00079.1 - 0.0015 18.8 1.8 0.0042 17.3 0.4 2.1 1 1 1 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_11 PF13414.6 AIO00079.1 - 0.0017 18.0 0.5 0.086 12.5 0.0 2.8 1 1 1 2 2 2 2 TPR repeat TPR_17 PF13431.6 AIO00079.1 - 0.0059 16.9 0.0 0.02 15.2 0.0 2.0 1 0 0 1 1 1 1 Tetratricopeptide repeat ANAPC5 PF12862.7 AIO00079.1 - 0.0094 16.0 1.0 0.21 11.7 0.1 3.2 2 1 0 2 2 2 1 Anaphase-promoting complex subunit 5 TPR_10 PF13374.6 AIO00079.1 - 0.027 14.4 0.3 0.2 11.6 0.3 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.6 AIO00079.1 - 0.05 14.3 1.4 1.1 10.0 1.3 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 AIO00079.1 - 0.11 13.4 1.5 0.35 11.8 0.1 2.8 2 0 0 2 2 1 0 Tetratricopeptide repeat Sigma70_ner PF04546.13 AIO00079.1 - 0.15 11.9 7.4 0.41 10.5 7.4 1.8 1 0 0 1 1 1 0 Sigma-70, non-essential region DUF4404 PF14357.6 AIO00079.1 - 0.18 12.5 0.1 0.18 12.5 0.1 4.0 3 1 1 4 4 4 0 Domain of unknown function (DUF4404) CMV_1a PF12467.8 AIO00079.1 - 0.59 10.5 4.6 0.24 11.7 0.5 2.4 2 0 0 2 2 2 0 Cucumber mosaic virus 1a protein family AAA_2 PF07724.14 AIO00081.1 - 1.6e-55 187.9 0.0 3.8e-53 180.1 0.0 3.4 3 0 0 3 3 3 1 AAA domain (Cdc48 subfamily) AAA_lid_9 PF17871.1 AIO00081.1 - 2.8e-36 123.6 2.3 2.8e-36 123.6 2.3 2.7 2 0 0 2 2 2 1 AAA lid domain AAA PF00004.29 AIO00081.1 - 1.3e-26 93.5 0.0 9.6e-15 55.2 0.0 3.1 4 0 0 4 4 2 2 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.9 AIO00081.1 - 2.6e-21 75.5 0.1 2.6e-21 75.5 0.1 3.3 4 0 0 4 4 2 1 C-terminal, D2-small domain, of ClpB protein AAA_5 PF07728.14 AIO00081.1 - 3.8e-15 56.1 0.3 2.1e-10 40.7 0.0 3.6 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) Clp_N PF02861.20 AIO00081.1 - 1.1e-10 41.4 4.0 5.6e-05 23.2 1.5 3.1 2 0 0 2 2 2 2 Clp amino terminal domain, pathogenicity island component AAA_16 PF13191.6 AIO00081.1 - 1.8e-08 35.0 11.0 0.0015 18.9 0.1 5.2 3 3 1 4 4 3 2 AAA ATPase domain AAA_22 PF13401.6 AIO00081.1 - 4.3e-08 33.5 1.5 0.043 14.1 0.0 4.7 2 2 0 3 3 3 2 AAA domain Sigma54_activat PF00158.26 AIO00081.1 - 9.7e-08 31.9 0.0 6.3e-05 22.7 0.0 3.0 2 1 0 2 2 2 1 Sigma-54 interaction domain TniB PF05621.11 AIO00081.1 - 4.5e-07 29.5 0.0 0.0003 20.3 0.0 3.5 2 1 0 2 2 2 1 Bacterial TniB protein IstB_IS21 PF01695.17 AIO00081.1 - 5.3e-07 29.5 0.0 0.018 14.8 0.0 2.8 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_14 PF13173.6 AIO00081.1 - 7e-07 29.3 0.0 0.029 14.4 0.0 3.4 2 0 0 2 2 2 2 AAA domain RuvB_N PF05496.12 AIO00081.1 - 2.5e-06 27.3 0.2 0.28 10.9 0.0 4.3 4 0 0 4 4 4 1 Holliday junction DNA helicase RuvB P-loop domain AAA_7 PF12775.7 AIO00081.1 - 9e-06 25.3 0.0 0.049 13.1 0.0 2.7 2 1 0 2 2 2 2 P-loop containing dynein motor region ATPase_2 PF01637.18 AIO00081.1 - 3.6e-05 23.8 5.5 0.73 9.7 0.1 4.3 3 1 1 4 4 4 2 ATPase domain predominantly from Archaea Zeta_toxin PF06414.12 AIO00081.1 - 0.0001 21.7 0.1 0.09 12.1 0.0 3.7 3 0 0 3 3 3 1 Zeta toxin AAA_18 PF13238.6 AIO00081.1 - 0.00027 21.5 0.2 0.36 11.4 0.0 3.8 2 1 1 3 3 3 1 AAA domain NACHT PF05729.12 AIO00081.1 - 0.00042 20.3 0.0 0.096 12.6 0.0 3.2 3 0 0 3 3 2 1 NACHT domain AAA_33 PF13671.6 AIO00081.1 - 0.00044 20.4 0.5 0.34 11.1 0.0 3.7 4 0 0 4 4 4 1 AAA domain Roc PF08477.13 AIO00081.1 - 0.00063 20.0 0.0 1.4 9.1 0.0 3.0 3 0 0 3 3 2 1 Ras of Complex, Roc, domain of DAPkinase TsaE PF02367.17 AIO00081.1 - 0.00068 19.6 0.0 2.5 8.1 0.0 2.9 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE Mg_chelatase PF01078.21 AIO00081.1 - 0.00099 18.5 0.1 5.4 6.3 0.1 3.7 2 1 0 2 2 2 0 Magnesium chelatase, subunit ChlI DUF815 PF05673.13 AIO00081.1 - 0.0012 18.1 0.1 0.3 10.2 0.1 2.9 2 1 0 2 2 2 1 Protein of unknown function (DUF815) ResIII PF04851.15 AIO00081.1 - 0.0012 18.9 0.0 0.23 11.4 0.0 3.7 3 1 0 3 3 3 1 Type III restriction enzyme, res subunit RNA_helicase PF00910.22 AIO00081.1 - 0.0016 18.8 0.0 1.9 8.9 0.0 2.9 2 0 0 2 2 2 1 RNA helicase TIP49 PF06068.13 AIO00081.1 - 0.0041 16.4 0.0 0.85 8.8 0.0 2.9 2 1 1 3 3 3 1 TIP49 P-loop domain DNA_pol3_delta2 PF13177.6 AIO00081.1 - 0.0047 16.7 0.8 1.4 8.6 0.0 3.4 3 1 0 3 3 3 1 DNA polymerase III, delta subunit RsgA_GTPase PF03193.16 AIO00081.1 - 0.0061 16.5 0.1 6.7 6.6 0.0 3.3 2 1 0 3 3 2 0 RsgA GTPase AAA_3 PF07726.11 AIO00081.1 - 0.0065 16.3 0.1 2.5 8.0 0.0 3.4 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.6 AIO00081.1 - 0.0075 16.6 1.4 0.41 11.0 0.2 3.7 2 2 0 3 3 3 1 AAA domain Bac_DnaA PF00308.18 AIO00081.1 - 0.0088 15.9 0.2 5.3 6.8 0.0 3.0 3 1 0 3 3 2 0 Bacterial dnaA protein NTPase_1 PF03266.15 AIO00081.1 - 0.0097 15.8 0.3 2.1 8.2 0.0 3.2 3 0 0 3 3 3 1 NTPase AAA_25 PF13481.6 AIO00081.1 - 0.01 15.4 3.7 0.62 9.6 0.0 3.8 3 1 0 3 3 3 0 AAA domain ABC_tran PF00005.27 AIO00081.1 - 0.012 16.1 1.4 16 6.0 0.0 3.9 4 0 0 4 4 3 0 ABC transporter AAA_29 PF13555.6 AIO00081.1 - 0.015 15.1 0.0 9.4 6.1 0.0 2.7 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_28 PF13521.6 AIO00081.1 - 0.038 14.2 0.1 15 5.8 0.0 3.3 3 0 0 3 3 2 0 AAA domain DUF4041 PF13250.6 AIO00081.1 - 0.16 11.9 0.3 0.82 9.6 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4041) DUF16 PF01519.16 AIO00081.1 - 0.21 12.1 7.9 0.37 11.3 2.9 3.1 1 1 1 2 2 2 0 Protein of unknown function DUF16 Spc7 PF08317.11 AIO00081.1 - 0.4 9.5 13.4 0.84 8.5 13.4 1.5 1 0 0 1 1 1 0 Spc7 kinetochore protein AAA_23 PF13476.6 AIO00081.1 - 0.65 10.5 19.6 1.9 8.9 0.0 4.4 3 1 0 3 3 1 0 AAA domain V_ATPase_I PF01496.19 AIO00081.1 - 0.88 7.4 3.6 1.3 6.9 3.6 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family APG6_N PF17675.1 AIO00081.1 - 3.1 8.3 12.0 10 6.7 12.0 2.0 1 0 0 1 1 1 0 Apg6 coiled-coil region eIF3_subunit PF08597.10 AIO00081.1 - 6 6.7 11.6 12 5.8 11.6 1.4 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit Lipase_3 PF01764.25 AIO00082.1 - 7.1e-25 87.5 0.0 1.7e-24 86.3 0.0 1.6 1 1 0 1 1 1 1 Lipase (class 3) MIG-14_Wnt-bd PF06664.12 AIO00082.1 - 8.5e-09 35.0 29.2 8.5e-09 35.0 29.2 1.8 2 0 0 2 2 2 1 Wnt-binding factor required for Wnt secretion PHO4 PF01384.20 AIO00082.1 - 0.14 11.2 3.7 8.2e+02 -1.2 8.5 2.3 1 1 0 1 1 1 0 Phosphate transporter family GvpG PF05120.12 AIO00082.1 - 0.19 11.7 0.0 0.37 10.8 0.0 1.4 1 0 0 1 1 1 0 Gas vesicle protein G Tnp_P_element_C PF12596.8 AIO00083.1 - 0.068 13.7 0.3 0.12 13.0 0.2 1.6 1 1 1 2 2 2 0 87kDa Transposase DSS1_SEM1 PF05160.13 AIO00083.1 - 0.069 13.2 10.9 0.15 12.1 10.9 1.7 1 1 0 1 1 1 0 DSS1/SEM1 family DUF3025 PF11227.8 AIO00083.1 - 0.082 12.7 0.0 0.11 12.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3025) Carn_acyltransf PF00755.20 AIO00085.1 - 1.3e-117 393.9 0.0 1.6e-117 393.6 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase RNA_pol_Rpc34 PF05158.12 AIO00086.1 - 1.9e-53 182.0 0.0 6.4e-53 180.3 0.0 1.8 1 1 0 1 1 1 1 RNA polymerase Rpc34 subunit TFIIE_alpha PF02002.17 AIO00086.1 - 0.038 13.8 0.0 0.071 13.0 0.0 1.4 1 0 0 1 1 1 0 TFIIE alpha subunit Pkinase PF00069.25 AIO00087.1 - 9.4e-63 212.0 0.0 3.2e-62 210.3 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 AIO00087.1 - 5.3e-33 114.4 0.0 4e-23 82.0 0.0 2.9 3 0 0 3 3 3 2 Protein tyrosine kinase Haspin_kinase PF12330.8 AIO00087.1 - 0.0032 16.5 0.1 0.017 14.1 0.0 1.9 2 0 0 2 2 2 1 Haspin like kinase domain Kdo PF06293.14 AIO00087.1 - 0.0033 16.8 0.4 0.0056 16.1 0.0 1.5 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 AIO00087.1 - 0.024 14.6 0.4 0.051 13.5 0.4 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 AIO00087.1 - 0.035 12.9 0.0 0.058 12.2 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase RRM_1 PF00076.22 AIO00088.1 - 3.8e-31 106.7 0.0 3.4e-19 68.4 0.0 3.4 2 1 1 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 AIO00088.1 - 5.4e-05 23.0 0.0 0.081 12.8 0.0 2.3 2 0 0 2 2 2 2 Occluded RNA-recognition motif RRM_7 PF16367.5 AIO00088.1 - 9.8e-05 22.4 0.0 0.0017 18.4 0.0 2.5 2 0 0 2 2 2 1 RNA recognition motif Limkain-b1 PF11608.8 AIO00088.1 - 0.00055 19.9 0.0 0.0096 16.0 0.0 2.8 2 1 1 3 3 3 1 Limkain b1 RRM_5 PF13893.6 AIO00088.1 - 0.002 17.7 0.0 0.0067 16.0 0.0 1.8 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 AIO00088.1 - 0.039 14.0 0.0 9.7 6.3 0.0 2.6 2 1 0 2 2 2 0 RNA binding motif DUF4384 PF14326.6 AIO00088.1 - 0.083 13.0 1.9 1.2 9.3 0.5 2.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4384) RRM_Rrp7 PF17799.1 AIO00088.1 - 0.18 11.6 0.0 0.32 10.8 0.0 1.3 1 0 0 1 1 1 0 Rrp7 RRM-like N-terminal domain Amastin PF07344.11 AIO00089.1 - 2.5e-43 147.6 13.1 2.9e-43 147.4 13.1 1.0 1 0 0 1 1 1 1 Amastin surface glycoprotein RRM_1 PF00076.22 AIO00090.1 - 8e-22 76.8 0.0 1.5e-10 40.7 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.22 AIO00091.1 - 4.6e-25 87.2 0.0 1.2e-12 47.5 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 AIO00091.1 - 0.012 15.2 0.2 0.72 9.5 0.1 2.5 1 1 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.8 AIO00091.1 - 0.014 15.4 0.3 0.21 11.7 0.0 2.8 2 1 0 2 2 2 0 Limkain b1 RRM_7 PF16367.5 AIO00091.1 - 0.16 12.1 0.0 0.87 9.7 0.0 2.2 2 0 0 2 2 2 0 RNA recognition motif OrsD PF12013.8 AIO00091.1 - 0.35 11.3 3.0 0.47 10.9 1.8 1.9 1 1 0 1 1 1 0 Orsellinic acid/F9775 biosynthesis cluster protein D RRM_1 PF00076.22 AIO00092.1 - 5.8e-26 90.1 0.1 5.5e-14 51.7 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 AIO00092.1 - 0.00051 20.1 0.0 0.077 13.1 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif PHM7_cyt PF14703.6 AIO00092.1 - 0.1 12.8 0.5 19 5.4 0.0 3.4 3 1 0 3 3 3 0 Cytosolic domain of 10TM putative phosphate transporter Nab6_mRNP_bdg PF10567.9 AIO00092.1 - 0.12 11.9 0.0 0.23 10.9 0.0 1.4 1 0 0 1 1 1 0 RNA-recognition motif RRM_1 PF00076.22 AIO00094.1 - 3e-20 71.8 0.1 8.7e-13 47.9 0.1 3.7 4 0 0 4 4 4 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 AIO00094.1 - 0.0045 17.1 0.1 3.5 7.8 0.0 2.9 3 0 0 3 3 3 2 RNA recognition motif RNA_bind PF08675.11 AIO00094.1 - 0.015 15.3 0.0 0.26 11.3 0.0 2.4 2 0 0 2 2 2 0 RNA binding domain zf-LYAR PF08790.11 AIO00095.1 - 5.8e-13 48.5 3.9 5.8e-13 48.5 3.9 2.1 2 0 0 2 2 2 1 LYAR-type C2HC zinc finger zf_UBZ PF18439.1 AIO00095.1 - 0.08 12.5 0.8 8.6 6.0 0.1 2.6 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger Clat_adaptor_s PF01217.20 AIO00098.1 - 1.2e-50 171.1 1.0 1.4e-50 170.9 1.0 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain PI3_PI4_kinase PF00454.27 AIO00099.1 - 2.4e-34 119.3 0.1 5.8e-31 108.2 0.1 2.5 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.20 AIO00099.1 - 3.5e-15 55.9 0.1 7e-15 54.9 0.1 1.4 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) DUF4135 PF13575.6 AIO00099.1 - 0.026 13.9 0.0 0.056 12.8 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4135) P3A PF08727.11 AIO00099.1 - 0.19 11.1 0.2 0.77 9.2 0.1 2.0 2 0 0 2 2 2 0 Poliovirus 3A protein like Ank_2 PF12796.7 AIO00101.1 - 1.1e-06 29.2 0.0 2.5e-06 28.0 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 AIO00101.1 - 7.6e-05 23.2 0.2 0.00021 21.8 0.2 1.8 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 AIO00101.1 - 0.00047 20.4 0.3 0.023 15.0 0.1 2.7 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 AIO00101.1 - 0.0079 16.6 0.0 0.97 10.2 0.0 2.7 2 0 0 2 2 2 1 Ankyrin repeat DUF533 PF04391.12 AIO00101.1 - 0.032 13.8 0.3 0.032 13.8 0.3 2.3 3 1 0 3 3 3 0 Protein of unknown function (DUF533) Ank PF00023.30 AIO00101.1 - 0.052 14.0 0.3 2 9.0 0.1 2.6 2 0 0 2 2 2 0 Ankyrin repeat Asn_synthase PF00733.21 AIO00102.1 - 2.3e-15 57.1 1.0 0.0011 18.7 0.0 4.0 3 1 1 4 4 4 3 Asparagine synthase SelP_N PF04592.14 AIO00102.1 - 0.22 10.9 1.6 0.37 10.2 1.6 1.3 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Nodulin-like PF06813.13 AIO00103.1 - 1.5e-10 41.0 10.0 1.5e-10 41.0 10.0 2.3 2 1 0 2 2 2 1 Nodulin-like MFS_1 PF07690.16 AIO00104.1 - 6e-15 55.0 41.6 7.5e-13 48.1 22.1 2.6 2 1 0 2 2 2 2 Major Facilitator Superfamily Nodulin-like PF06813.13 AIO00104.1 - 1e-11 44.8 17.6 1e-11 44.8 17.6 2.2 2 1 0 2 2 2 1 Nodulin-like BCLP PF12304.8 AIO00104.1 - 0.61 9.6 6.6 0.15 11.6 1.0 2.6 2 1 1 3 3 3 0 Beta-casein like protein MFS_1 PF07690.16 AIO00105.1 - 1.2e-19 70.5 32.7 4.1e-14 52.3 22.0 2.4 2 0 0 2 2 2 2 Major Facilitator Superfamily Nodulin-like PF06813.13 AIO00105.1 - 1.1e-11 44.7 17.5 1.1e-11 44.7 17.5 2.4 2 1 0 2 2 2 1 Nodulin-like MotA_ExbB PF01618.16 AIO00105.1 - 0.22 11.3 1.1 1.1 9.0 0.1 2.6 2 0 0 2 2 2 0 MotA/TolQ/ExbB proton channel family BCLP PF12304.8 AIO00105.1 - 0.4 10.2 6.4 0.13 11.8 0.9 2.9 2 1 1 3 3 3 0 Beta-casein like protein BTK PF00779.19 AIO00108.1 - 0.092 12.6 0.5 0.24 11.3 0.5 1.7 1 0 0 1 1 1 0 BTK motif Toxin_32 PF08120.11 AIO00108.1 - 0.56 10.1 4.4 7.9 6.4 0.5 2.3 2 0 0 2 2 2 0 Tamulustoxin family RabGAP-TBC PF00566.18 AIO00109.1 - 1.9e-44 151.9 0.0 2.6e-44 151.5 0.0 1.1 1 0 0 1 1 1 1 Rab-GTPase-TBC domain DUF3135 PF11333.8 AIO00109.1 - 0.071 13.4 3.2 0.14 12.5 3.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3135) LisH PF08513.11 AIO00109.1 - 0.09 12.8 0.0 0.31 11.1 0.0 1.9 1 0 0 1 1 1 0 LisH Peptidase_M20 PF01546.28 AIO00110.1 - 6e-36 124.1 0.0 7.4e-36 123.8 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 AIO00110.1 - 4.7e-19 68.3 0.0 7.6e-19 67.6 0.0 1.3 1 0 0 1 1 1 1 Peptidase dimerisation domain WD40 PF00400.32 AIO00111.1 - 2.3e-05 25.0 0.0 0.023 15.5 0.0 2.8 2 0 0 2 2 2 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 AIO00111.1 - 0.00014 22.1 0.0 0.0013 19.0 0.0 2.4 2 1 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain XPC-binding PF09280.11 AIO00112.1 - 1.7e-06 27.6 3.3 3.6e-06 26.6 3.3 1.6 1 0 0 1 1 1 1 XPC-binding domain UBA PF00627.31 AIO00112.1 - 1.4e-05 24.9 0.6 7.6e-05 22.5 0.0 2.4 2 0 0 2 2 2 1 UBA/TS-N domain MmoB_DmpM PF02406.17 AIO00112.1 - 0.016 15.4 0.4 9.4 6.5 0.0 2.6 2 0 0 2 2 2 0 MmoB/DmpM family PPP4R2 PF09184.11 AIO00112.1 - 1.9 8.0 12.2 4 7.0 2.6 2.3 2 0 0 2 2 2 0 PPP4R2 EMP70 PF02990.16 AIO00115.1 - 3e-146 488.1 11.1 3.7e-146 487.8 11.1 1.1 1 0 0 1 1 1 1 Endomembrane protein 70 SYS1 PF09801.9 AIO00116.1 - 5.9e-20 71.9 2.3 2e-17 63.7 0.6 2.2 2 0 0 2 2 2 2 Integral membrane protein S linking to the trans Golgi network DUF5368 PF17336.2 AIO00116.1 - 0.11 12.7 1.4 0.14 12.4 0.0 1.8 2 0 0 2 2 2 0 Family of unknown function (DUF5368) dsrm PF00035.26 AIO00117.1 - 1.9e-09 38.1 0.0 0.74 10.6 0.0 5.8 5 0 0 5 5 5 4 Double-stranded RNA binding motif BUD22 PF09073.10 AIO00117.1 - 2.2 7.5 4.6 3.6 6.8 4.6 1.2 1 0 0 1 1 1 0 BUD22 DNA_pol_phi PF04931.13 AIO00117.1 - 3.7 5.5 7.7 5.5 5.0 7.7 1.1 1 0 0 1 1 1 0 DNA polymerase phi RINGv PF12906.7 AIO00118.1 - 3e-11 43.3 9.9 7e-11 42.1 9.9 1.7 1 0 0 1 1 1 1 RING-variant domain zf-RING_2 PF13639.6 AIO00118.1 - 0.05 13.9 7.8 0.097 13.0 7.8 1.5 1 0 0 1 1 1 0 Ring finger domain Phage_holin_2_4 PF16082.5 AIO00118.1 - 0.17 11.7 1.5 3 7.7 0.1 2.6 2 0 0 2 2 2 0 Bacteriophage holin family, superfamily II-like zf-RING-like PF08746.11 AIO00118.1 - 3.2 8.2 6.8 6.2 7.2 6.8 1.5 1 0 0 1 1 1 0 RING-like domain ABC_tran PF00005.27 AIO00119.1 - 4.8e-27 95.1 0.1 1.5e-26 93.5 0.0 1.8 2 0 0 2 2 2 1 ABC transporter AAA_21 PF13304.6 AIO00119.1 - 1.1e-06 28.7 0.4 0.00023 21.1 0.0 2.2 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 AIO00119.1 - 0.00041 19.9 0.0 0.0047 16.4 0.0 2.1 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain T6SS_VipA PF05591.12 AIO00119.1 - 0.0081 16.0 0.2 0.014 15.2 0.2 1.3 1 0 0 1 1 1 1 Type VI secretion system, VipA, VC_A0107 or Hcp2 T2SSE PF00437.20 AIO00119.1 - 0.023 13.8 0.0 0.039 13.0 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein IstB_IS21 PF01695.17 AIO00119.1 - 0.037 13.8 0.0 3.5 7.3 0.0 2.3 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_29 PF13555.6 AIO00119.1 - 0.043 13.5 0.1 0.17 11.6 0.0 2.0 2 0 0 2 2 2 0 P-loop containing region of AAA domain SbcCD_C PF13558.6 AIO00119.1 - 0.065 13.5 2.0 0.93 9.8 0.3 3.1 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_16 PF13191.6 AIO00119.1 - 0.072 13.5 0.0 0.18 12.2 0.0 1.8 1 0 0 1 1 1 0 AAA ATPase domain RsgA_GTPase PF03193.16 AIO00119.1 - 0.1 12.5 0.0 0.19 11.6 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase AAA_23 PF13476.6 AIO00119.1 - 0.1 13.1 0.2 0.39 11.2 0.1 1.9 2 0 0 2 2 2 0 AAA domain Thioredoxin PF00085.20 AIO00120.1 - 8.8e-08 32.1 0.0 0.0002 21.3 0.0 2.4 2 0 0 2 2 2 2 Thioredoxin Redoxin PF08534.10 AIO00120.1 - 0.0039 16.9 0.8 0.02 14.6 0.0 2.4 3 0 0 3 3 3 1 Redoxin AhpC-TSA PF00578.21 AIO00120.1 - 0.019 14.9 0.0 0.04 13.8 0.0 1.5 1 0 0 1 1 1 0 AhpC/TSA family DHR10 PF18595.1 AIO00121.1 - 0.011 15.7 2.9 0.011 15.7 2.9 1.8 2 0 0 2 2 2 0 Designed helical repeat protein 10 domain FUSC PF04632.12 AIO00121.1 - 0.02 13.5 1.7 0.023 13.3 1.7 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family Spc7 PF08317.11 AIO00121.1 - 0.2 10.5 2.5 0.12 11.2 0.7 1.5 2 0 0 2 2 2 0 Spc7 kinetochore protein DUF948 PF06103.11 AIO00121.1 - 0.24 11.7 1.5 0.54 10.6 0.3 2.2 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) ABC_tran_CTD PF16326.5 AIO00121.1 - 2.9 8.2 8.9 0.67 10.2 1.9 2.8 3 0 0 3 3 3 0 ABC transporter C-terminal domain 4HBT PF03061.22 AIO00122.1 - 2.3e-14 53.5 1.8 1.6e-09 38.0 0.6 2.3 2 0 0 2 2 2 2 Thioesterase superfamily MaoC_dehydratas PF01575.19 AIO00122.1 - 0.032 13.8 0.1 0.86 9.2 0.2 2.5 2 0 0 2 2 2 0 MaoC like domain 4HBT_2 PF13279.6 AIO00122.1 - 0.15 12.5 1.0 4.4 7.8 0.7 2.6 2 1 0 2 2 2 0 Thioesterase-like superfamily MORN PF02493.20 AIO00123.1 - 1.5e-52 172.5 93.7 3.1e-06 26.7 1.6 21.3 21 0 0 21 21 21 19 MORN repeat MutS_III PF05192.18 AIO00124.1 - 1.2e-17 64.8 0.0 2.1e-17 64.0 0.0 1.5 1 0 0 1 1 1 1 MutS domain III MutS_V PF00488.21 AIO00124.1 - 1.7e-15 57.6 0.2 3.1e-08 33.9 0.1 2.5 2 0 0 2 2 2 2 MutS domain V AAA_29 PF13555.6 AIO00124.1 - 0.0092 15.7 0.0 0.021 14.6 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_30 PF13604.6 AIO00124.1 - 0.0098 15.6 0.1 0.025 14.3 0.1 1.7 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 AIO00124.1 - 0.018 15.4 0.1 0.064 13.6 0.1 1.9 1 0 0 1 1 1 0 AAA ATPase domain AAA_27 PF13514.6 AIO00124.1 - 0.19 11.3 0.0 0.38 10.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain Flagellar_rod PF05149.12 AIO00125.1 - 3.7e-104 348.2 29.2 3.7e-104 348.2 29.2 2.8 2 1 1 3 3 3 2 Paraflagellar rod protein Diphthamide_syn PF01866.17 AIO00126.1 - 9.4e-113 376.6 0.0 1.2e-112 376.3 0.0 1.1 1 0 0 1 1 1 1 Putative diphthamide synthesis protein BRCT PF00533.26 AIO00127.1 - 7.9e-10 39.0 0.0 0.088 13.2 0.0 4.9 6 0 0 6 6 6 3 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.7 AIO00127.1 - 7.5e-08 32.2 4.7 0.068 13.1 0.8 5.3 5 1 0 5 5 5 2 twin BRCT domain RTT107_BRCT_5 PF16770.5 AIO00127.1 - 7.7e-08 32.1 0.0 3.4e-07 30.0 0.0 2.1 2 0 0 2 2 2 1 Regulator of Ty1 transposition protein 107 BRCT domain BRCT_2 PF16589.5 AIO00127.1 - 4.1e-06 27.1 0.0 0.57 10.6 0.0 4.0 4 0 0 4 4 4 2 BRCT domain, a BRCA1 C-terminus domain BRCT_3 PF18428.1 AIO00127.1 - 0.00063 19.8 6.1 2.3 8.3 0.2 4.4 4 0 0 4 4 4 2 BRCA1 C Terminus (BRCT) domain Ins_P5_2-kin PF06090.12 AIO00127.1 - 0.16 11.4 0.0 0.3 10.5 0.0 1.4 1 0 0 1 1 1 0 Inositol-pentakisphosphate 2-kinase Ribosomal_S8 PF00410.19 AIO00128.1 - 5.4e-21 74.9 0.0 6.8e-21 74.5 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S8 Folliculin PF11704.8 AIO00130.1 - 7.1e-08 32.5 1.7 9.1e-08 32.2 0.0 2.0 2 1 0 2 2 2 1 Vesicle coat protein involved in Golgi to plasma membrane transport Folliculin_C PF16692.5 AIO00130.1 - 2.1e-07 30.9 0.0 3.8e-07 30.1 0.0 1.4 1 0 0 1 1 1 1 Folliculin C-terminal domain CENP-X PF09415.10 AIO00130.1 - 0.22 11.9 2.7 4.7 7.6 0.0 2.8 1 1 1 2 2 2 0 CENP-S associating Centromere protein X Bac_surface_Ag PF01103.23 AIO00131.1 - 2.7e-20 73.1 0.4 3.6e-20 72.7 0.4 1.2 1 0 0 1 1 1 1 Surface antigen Pyr_redox_2 PF07992.14 AIO00132.1 - 3e-45 154.7 0.1 4.8e-45 154.1 0.1 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 AIO00132.1 - 1.5e-19 70.3 0.2 4.5e-19 68.7 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 AIO00132.1 - 1.3e-18 67.3 2.3 2.4e-16 60.0 0.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 AIO00132.1 - 2.8e-08 33.5 0.1 4.5e-08 32.9 0.1 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase DAO PF01266.24 AIO00132.1 - 2.1e-06 27.6 5.6 0.00049 19.8 0.1 3.1 2 1 0 3 3 3 2 FAD dependent oxidoreductase GIDA PF01134.22 AIO00132.1 - 2.2e-06 27.0 2.3 0.018 14.1 0.1 3.7 4 0 0 4 4 4 2 Glucose inhibited division protein A HI0933_like PF03486.14 AIO00132.1 - 6.7e-06 25.1 1.5 0.002 16.9 0.5 3.4 3 0 0 3 3 3 1 HI0933-like protein FAD_binding_3 PF01494.19 AIO00132.1 - 1.5e-05 24.5 0.0 0.022 14.0 0.0 3.1 3 0 0 3 3 3 2 FAD binding domain Pyr_redox_3 PF13738.6 AIO00132.1 - 1.6e-05 24.4 11.0 0.006 15.9 0.6 4.0 4 1 1 5 5 5 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 AIO00132.1 - 1.9e-05 24.0 0.0 5.6e-05 22.4 0.0 1.7 2 1 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) FAD_binding_2 PF00890.24 AIO00132.1 - 0.00046 19.4 1.0 0.00046 19.4 1.0 2.7 4 0 0 4 4 4 1 FAD binding domain AlaDh_PNT_C PF01262.21 AIO00132.1 - 0.00065 19.1 0.1 0.53 9.5 0.1 2.3 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain Thi4 PF01946.17 AIO00132.1 - 0.00088 18.6 0.1 0.084 12.1 0.0 2.4 2 0 0 2 2 2 1 Thi4 family ThiF PF00899.21 AIO00132.1 - 0.00089 18.7 0.0 0.0019 17.6 0.0 1.5 1 0 0 1 1 1 1 ThiF family 3HCDH_N PF02737.18 AIO00132.1 - 0.0099 15.8 0.0 0.02 14.8 0.0 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_8 PF13450.6 AIO00132.1 - 0.011 16.0 3.8 1.3 9.3 0.7 2.6 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 AIO00132.1 - 0.012 14.7 0.5 1.2 8.1 0.4 2.2 2 0 0 2 2 2 0 Lycopene cyclase protein 2-Hacid_dh_C PF02826.19 AIO00132.1 - 0.039 13.3 0.1 0.11 11.8 0.0 1.8 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DUF1314 PF07013.11 AIO00132.1 - 0.13 12.1 0.0 0.34 10.7 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1314) XPG_N PF00752.17 AIO00133.1 - 0.03 14.8 0.1 0.12 12.9 0.0 2.0 2 0 0 2 2 2 0 XPG N-terminal domain Glyco_hydro_67C PF07477.12 AIO00133.1 - 0.05 13.1 1.8 0.07 12.7 0.5 1.8 2 0 0 2 2 2 0 Glycosyl hydrolase family 67 C-terminus FlaC_arch PF05377.11 AIO00133.1 - 0.18 12.2 10.5 1.9 9.0 0.1 4.6 4 1 0 5 5 5 0 Flagella accessory protein C (FlaC) BLOC1_2 PF10046.9 AIO00133.1 - 0.22 11.8 14.5 4 7.8 0.0 4.2 2 1 2 5 5 5 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF1993 PF09351.10 AIO00133.1 - 0.27 11.3 8.6 0.26 11.4 4.2 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF1993) Sugarporin_N PF11471.8 AIO00133.1 - 0.34 10.9 6.4 4.4 7.3 0.6 3.3 1 1 1 2 2 2 0 Maltoporin periplasmic N-terminal extension Filament PF00038.21 AIO00133.1 - 0.45 10.0 27.4 0.25 10.9 3.7 2.8 1 1 1 2 2 2 0 Intermediate filament protein DUF1664 PF07889.12 AIO00133.1 - 0.45 10.6 18.7 0.61 10.1 6.4 3.5 2 2 1 3 3 3 0 Protein of unknown function (DUF1664) Cnn_1N PF07989.11 AIO00133.1 - 0.8 9.9 21.4 0.18 12.0 0.9 4.5 2 2 1 3 3 3 0 Centrosomin N-terminal motif 1 Ribosomal_S30AE PF02482.19 AIO00133.1 - 0.88 10.4 6.6 12 6.8 0.6 3.8 2 2 1 3 3 3 0 Sigma 54 modulation protein / S30EA ribosomal protein DOG1 PF14144.6 AIO00133.1 - 1.1 9.6 9.2 0.12 12.6 0.8 3.3 3 1 0 3 3 3 0 Seed dormancy control DUF2730 PF10805.8 AIO00133.1 - 1.9 8.6 11.2 4.6 7.4 0.7 4.0 1 1 2 3 3 3 0 Protein of unknown function (DUF2730) Snapin_Pallidin PF14712.6 AIO00133.1 - 2.2 8.8 28.6 0.92 10.0 1.3 4.7 2 2 2 4 4 4 0 Snapin/Pallidin NPV_P10 PF05531.12 AIO00133.1 - 2.3 8.8 17.4 14 6.2 0.1 4.7 3 1 2 5 5 5 0 Nucleopolyhedrovirus P10 protein TolA_bind_tri PF16331.5 AIO00133.1 - 2.7 8.1 37.6 1.4 9.1 3.7 5.1 2 1 1 4 4 4 0 TolA binding protein trimerisation DIT1_PvcA PF05141.12 AIO00133.1 - 3.4 7.1 12.6 3.3 7.1 3.8 2.3 1 1 0 2 2 2 0 Pyoverdine/dityrosine biosynthesis protein Cep57_CLD PF14073.6 AIO00133.1 - 3.6 7.6 31.1 0.15 12.0 21.0 2.2 1 1 0 2 2 2 0 Centrosome localisation domain of Cep57 ABC_tran_CTD PF16326.5 AIO00133.1 - 7.1 7.0 23.3 0.1 12.8 3.9 3.4 2 1 1 3 3 3 0 ABC transporter C-terminal domain FapA PF03961.13 AIO00133.1 - 7.8 5.0 14.6 4.6 5.7 1.4 2.2 1 1 0 2 2 2 0 Flagellar Assembly Protein A DASH_Hsk3 PF08227.11 AIO00133.1 - 9.7 6.6 14.6 20 5.6 0.6 4.3 3 1 0 3 3 3 0 DASH complex subunit Hsk3 like PIH1_CS PF18201.1 AIO00134.1 - 2.3e-08 34.3 0.0 3.8e-08 33.7 0.0 1.3 1 0 0 1 1 1 1 PIH1 CS-like domain zf_C2H2_10 PF18414.1 AIO00136.1 - 0.017 14.6 0.1 0.026 14.1 0.1 1.2 1 0 0 1 1 1 0 C2H2 type zinc-finger zf-C2H2_12 PF18658.1 AIO00136.1 - 0.052 13.1 0.1 0.087 12.4 0.1 1.3 1 0 0 1 1 1 0 Zinc-finger C2H2-type zf-met2 PF12907.7 AIO00136.1 - 0.25 11.5 3.3 2.3 8.4 3.3 2.3 1 1 0 1 1 1 0 Zinc-binding DnaJ PF00226.31 AIO00138.1 - 5.4e-08 32.8 0.0 1.5e-07 31.4 0.0 1.7 1 0 0 1 1 1 1 DnaJ domain PCEMA1 PF07418.11 AIO00138.1 - 0.16 11.5 0.3 0.36 10.3 0.3 1.5 1 0 0 1 1 1 0 Acidic phosphoprotein precursor PCEMA1 Rad50_zn_hook PF04423.14 AIO00139.1 - 0.15 12.0 1.2 0.31 10.9 0.2 2.0 2 0 0 2 2 2 0 Rad50 zinc hook motif Zn_ribbon_recom PF13408.6 AIO00139.1 - 0.25 11.9 1.5 0.55 10.8 1.5 1.5 1 0 0 1 1 1 0 Recombinase zinc beta ribbon domain zf-C2H2_4 PF13894.6 AIO00139.1 - 1.2 10.2 4.6 3.7 8.6 4.6 1.9 1 0 0 1 1 1 0 C2H2-type zinc finger PDEase_I_N PF08499.12 AIO00140.1 - 0.63 9.9 2.4 11 5.9 0.1 2.5 2 0 0 2 2 2 0 3'5'-cyclic nucleotide phosphodiesterase N-terminal LigD_N PF13298.6 AIO00141.1 - 0.026 14.8 0.0 0.045 14.0 0.0 1.3 1 0 0 1 1 1 0 DNA polymerase Ligase (LigD) EF-hand_7 PF13499.6 AIO00142.1 - 3.2e-13 49.9 0.0 0.00017 22.0 0.0 4.5 4 0 0 4 4 4 3 EF-hand domain pair EF-hand_6 PF13405.6 AIO00142.1 - 0.00011 21.9 0.0 0.76 9.9 0.0 4.1 4 0 0 4 4 4 1 EF-hand domain EF-hand_1 PF00036.32 AIO00142.1 - 0.01 15.3 2.0 0.42 10.3 0.1 4.0 5 0 0 5 5 5 0 EF hand EF-hand_13 PF17958.1 AIO00142.1 - 0.023 14.5 0.0 7.6 6.4 0.0 2.8 2 0 0 2 2 2 0 EF-hand domain EF-hand_5 PF13202.6 AIO00142.1 - 2.5 7.8 3.6 2.7 7.6 0.1 2.7 3 0 0 3 3 3 0 EF hand PPTA PF01239.22 AIO00144.1 - 4.5e-18 64.3 14.5 6.5e-08 32.0 0.3 5.4 5 0 0 5 5 5 4 Protein prenyltransferase alpha subunit repeat HTH_Tnp_Tc5 PF03221.16 AIO00144.1 - 0.047 13.7 0.1 2.6 8.2 0.0 3.1 3 0 0 3 3 3 0 Tc5 transposase DNA-binding domain Fumerase_C PF05683.12 AIO00145.1 - 7.1e-89 296.6 0.0 1.2e-88 295.8 0.0 1.4 1 0 0 1 1 1 1 Fumarase C-terminus Fumerase PF05681.14 AIO00145.1 - 4.3e-80 269.0 0.0 5.6e-80 268.6 0.0 1.1 1 0 0 1 1 1 1 Fumarate hydratase (Fumerase) DUF3450 PF11932.8 AIO00146.1 - 0.035 13.4 0.2 0.035 13.4 0.2 7.4 6 1 2 8 8 8 0 Protein of unknown function (DUF3450) Fib_alpha PF08702.10 AIO00146.1 - 0.088 13.0 30.3 0.061 13.5 5.2 6.2 4 1 1 5 5 5 0 Fibrinogen alpha/beta chain family Dehalogenase PF13486.6 AIO00146.1 - 0.22 10.9 0.6 0.66 9.3 0.0 2.1 2 0 0 2 2 2 0 Reductive dehalogenase subunit NDT80_PhoG PF05224.12 AIO00146.1 - 0.73 10.0 2.8 2.3 8.4 2.8 1.9 1 0 0 1 1 1 0 NDT80 / PhoG like DNA-binding family Methyltr_RsmB-F PF01189.17 AIO00149.1 - 3.1e-17 62.9 0.0 2.2e-07 30.7 0.0 3.6 3 0 0 3 3 3 3 16S rRNA methyltransferase RsmB/F PPR_2 PF13041.6 AIO00150.1 - 1.3e-05 25.2 0.0 0.023 14.9 0.0 3.3 3 0 0 3 3 3 2 PPR repeat family PPR PF01535.20 AIO00150.1 - 0.028 14.6 0.0 27 5.3 0.0 3.9 5 0 0 5 5 5 0 PPR repeat PPR_3 PF13812.6 AIO00150.1 - 0.04 14.0 0.0 35 4.6 0.0 3.5 3 1 0 3 3 3 0 Pentatricopeptide repeat domain TetR_C_24 PF17932.1 AIO00150.1 - 0.045 14.0 0.5 0.18 12.1 0.5 2.1 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain Pkinase PF00069.25 AIO00151.1 - 2e-73 247.0 0.0 2.8e-73 246.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 AIO00151.1 - 5.9e-40 137.2 0.0 8.5e-40 136.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 AIO00151.1 - 1.8e-06 27.5 0.0 6.9e-06 25.6 0.0 1.8 2 0 0 2 2 2 1 Kinase-like RIO1 PF01163.22 AIO00151.1 - 2.7e-05 23.9 0.2 0.00041 20.0 0.1 2.1 1 1 1 2 2 2 1 RIO1 family Kdo PF06293.14 AIO00151.1 - 0.00014 21.3 0.1 0.00025 20.5 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 AIO00151.1 - 0.00068 18.7 0.1 0.0011 18.1 0.1 1.2 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 AIO00151.1 - 0.0031 17.5 0.5 0.16 11.9 0.1 2.6 3 0 0 3 3 3 1 Phosphotransferase enzyme family Gpi1 PF05024.15 AIO00152.1 - 1.1e-39 136.5 1.7 2.6e-39 135.2 1.7 1.7 1 0 0 1 1 1 1 N-acetylglucosaminyl transferase component (Gpi1) DUF1249 PF06853.12 AIO00153.1 - 2.2 8.3 5.9 6.5 6.8 2.7 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF1249) Cse1 PF08506.10 AIO00155.1 - 0.064 12.1 0.0 0.16 10.8 0.0 1.6 1 0 0 1 1 1 0 Cse1 HEAT PF02985.22 AIO00155.1 - 0.1 12.9 0.0 1.1 9.7 0.0 2.9 2 0 0 2 2 2 0 HEAT repeat adh_short PF00106.25 AIO00157.1 - 5.1e-05 22.8 0.0 0.00075 19.0 0.0 2.5 2 1 0 2 2 2 1 short chain dehydrogenase ApbA PF02558.16 AIO00157.1 - 0.13 11.9 0.2 1.8 8.2 0.1 2.2 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA Babuvirus_MP PF07234.11 AIO00157.1 - 0.22 11.7 0.7 0.57 10.4 0.5 1.8 2 0 0 2 2 2 0 Movement and RNA silencing protein DUF1289 PF06945.13 AIO00158.1 - 0.34 10.7 2.6 0.66 9.8 2.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1289) AAA_12 PF13087.6 AIO00159.1 - 6.4e-34 117.3 0.0 1e-33 116.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 AIO00159.1 - 5.9e-14 52.5 5.2 3.1e-09 37.0 0.9 3.0 3 1 0 3 3 3 2 AAA domain AAA_30 PF13604.6 AIO00159.1 - 1.1e-07 31.8 1.1 0.0014 18.4 0.0 3.0 3 0 0 3 3 3 2 AAA domain AAA_19 PF13245.6 AIO00159.1 - 3.4e-05 24.2 0.4 0.34 11.2 0.0 3.0 2 1 0 2 2 2 2 AAA domain PhoH PF02562.16 AIO00159.1 - 0.0013 18.2 0.1 0.18 11.3 0.0 3.2 3 0 0 3 3 3 1 PhoH-like protein AAA_22 PF13401.6 AIO00159.1 - 0.0037 17.5 0.1 0.98 9.7 0.0 3.7 3 0 0 3 3 3 1 AAA domain Viral_helicase1 PF01443.18 AIO00159.1 - 0.017 14.9 1.2 2 8.1 0.0 3.3 3 0 0 3 3 3 0 Viral (Superfamily 1) RNA helicase DUF2075 PF09848.9 AIO00159.1 - 0.019 14.3 0.0 0.039 13.2 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) CSD PF00313.22 AIO00159.1 - 0.11 12.4 0.1 0.25 11.2 0.1 1.6 1 0 0 1 1 1 0 'Cold-shock' DNA-binding domain zf-C2H2_10 PF16588.5 AIO00159.1 - 0.23 11.2 5.8 0.52 10.1 5.8 1.6 1 0 0 1 1 1 0 C2H2 zinc-finger AAA_33 PF13671.6 AIO00159.1 - 5.2 7.2 7.0 5.2 7.2 0.0 3.8 4 0 0 4 4 4 0 AAA domain DUF4139 PF13598.6 AIO00160.1 - 2.2e-32 112.5 0.0 3.1e-32 112.0 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4139) Glyco_transf_24 PF18404.1 AIO00161.1 - 1e-127 425.1 1.8 1.6e-127 424.5 1.8 1.3 1 0 0 1 1 1 1 Glucosyltransferase 24 Thioredoxin_14 PF18402.1 AIO00161.1 - 8.1e-26 91.5 0.3 2.2e-23 83.5 0.0 2.6 2 0 0 2 2 2 2 Thioredoxin-like domain Thioredoxin_13 PF18401.1 AIO00161.1 - 2.5e-23 82.5 0.1 1.7e-20 73.3 0.0 3.2 3 0 0 3 3 3 2 Thioredoxin-like domain Thioredoxin_12 PF18400.1 AIO00161.1 - 6.2e-12 45.8 0.1 2e-11 44.1 0.1 1.9 1 0 0 1 1 1 1 Thioredoxin-like domain UDP-g_GGTase PF06427.11 AIO00161.1 - 1.4e-11 44.5 0.0 3.1e-11 43.4 0.0 1.6 1 0 0 1 1 1 1 UDP-glucose:Glycoprotein Glucosyltransferase Glyco_transf_8 PF01501.20 AIO00161.1 - 5.9e-05 22.7 0.2 0.00011 21.8 0.2 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 8 VIT1 PF01988.19 AIO00162.1 - 1.5e-11 44.6 1.8 6.7e-11 42.5 1.5 2.0 1 1 0 1 1 1 1 VIT family LRR_4 PF12799.7 AIO00163.1 - 6.3e-12 45.5 16.7 0.051 14.0 0.8 5.6 4 2 3 7 7 7 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 AIO00163.1 - 4.4e-05 23.1 14.9 0.031 14.1 0.6 5.5 3 2 3 6 6 6 5 Leucine rich repeat FNIP PF05725.12 AIO00163.1 - 0.013 15.6 4.3 2.2 8.5 0.1 4.2 3 1 1 4 4 4 0 FNIP Repeat LRR_1 PF00560.33 AIO00163.1 - 0.014 15.8 18.6 21 6.2 0.3 7.5 7 2 0 7 7 7 0 Leucine Rich Repeat LRR_6 PF13516.6 AIO00163.1 - 0.042 13.9 13.3 14 6.0 0.0 7.2 9 0 0 9 9 9 0 Leucine Rich repeat ERG2_Sigma1R PF04622.12 AIO00164.1 - 4.7e-79 264.6 0.2 5.6e-79 264.3 0.2 1.0 1 0 0 1 1 1 1 ERG2 and Sigma1 receptor like protein Pkinase PF00069.25 AIO00165.1 - 2e-37 129.0 0.0 5.9e-37 127.5 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 AIO00165.1 - 1.6e-15 57.1 0.0 3.6e-15 56.0 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 AIO00165.1 - 0.15 11.4 0.0 2.2 7.5 0.0 2.1 2 0 0 2 2 2 0 Kinase-like GDI PF00996.18 AIO00166.1 - 1.6e-176 587.1 0.0 1.8e-176 586.9 0.0 1.0 1 0 0 1 1 1 1 GDP dissociation inhibitor NAD_binding_8 PF13450.6 AIO00166.1 - 0.15 12.3 0.0 0.51 10.6 0.0 1.9 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain DTW PF03942.15 AIO00167.1 - 9.8e-31 107.0 0.0 1.9e-30 106.0 0.0 1.5 1 0 0 1 1 1 1 DTW domain Papo_T_antigen PF02380.15 AIO00167.1 - 0.061 13.5 0.2 0.061 13.5 0.2 1.8 2 0 0 2 2 2 0 T-antigen specific domain DUF4379 PF14311.6 AIO00168.1 - 1.1e-42 144.2 14.1 7.6e-16 58.2 1.0 3.4 3 0 0 3 3 3 3 Probable Zinc-ribbon domain HypA PF01155.19 AIO00168.1 - 4.6e-05 23.4 7.6 0.33 11.0 0.0 3.3 1 1 2 3 3 3 3 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Zn-ribbon_8 PF09723.10 AIO00168.1 - 0.00048 20.2 10.1 0.15 12.2 0.1 3.6 3 0 0 3 3 3 3 Zinc ribbon domain Zn_Tnp_IS91 PF14319.6 AIO00168.1 - 0.077 13.0 0.4 0.077 13.0 0.4 3.5 3 1 0 3 3 3 0 Transposase zinc-binding domain DUF2072 PF09845.9 AIO00168.1 - 0.24 11.7 1.5 0.43 10.8 0.2 2.1 2 0 0 2 2 2 0 Zn-ribbon containing protein zf-PHD-like PF15446.6 AIO00168.1 - 0.59 9.7 4.8 13 5.4 0.6 2.9 2 1 1 3 3 3 0 PHD/FYVE-zinc-finger like domain zf_Rg PF17915.1 AIO00168.1 - 5 6.6 6.2 19 4.8 0.1 3.1 3 0 0 3 3 3 0 Reverse gyrase zinc finger FeS_assembly_P PF01883.19 AIO00169.1 - 0.054 13.7 0.1 1.9 8.7 0.1 2.7 2 0 0 2 2 2 0 Iron-sulfur cluster assembly protein Dynamin_M PF01031.20 AIO00170.1 - 5.1e-82 275.3 0.2 1e-81 274.3 0.2 1.4 1 0 0 1 1 1 1 Dynamin central region Dynamin_N PF00350.23 AIO00170.1 - 2.8e-50 170.6 0.1 1.2e-49 168.6 0.0 2.1 2 0 0 2 2 2 1 Dynamin family GED PF02212.18 AIO00170.1 - 1.8e-24 85.7 0.3 6.4e-24 83.9 0.3 2.0 1 0 0 1 1 1 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.23 AIO00170.1 - 7e-05 22.9 0.2 0.00095 19.2 0.2 2.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase Baculo_p74 PF04583.12 AIO00170.1 - 0.009 15.5 0.0 0.018 14.5 0.0 1.4 1 0 0 1 1 1 1 Baculoviridae p74 conserved region AAA_15 PF13175.6 AIO00170.1 - 0.016 15.0 1.0 0.48 10.1 0.0 2.6 3 0 0 3 3 3 0 AAA ATPase domain p450 PF00067.22 AIO00170.1 - 0.018 13.8 0.0 0.038 12.8 0.0 1.4 1 0 0 1 1 1 0 Cytochrome P450 FeoB_N PF02421.18 AIO00170.1 - 0.036 13.6 0.9 4.2 6.9 0.0 2.9 3 0 0 3 3 3 0 Ferrous iron transport protein B AF0941-like PF14591.6 AIO00170.1 - 0.087 13.4 1.4 9.8 6.8 0.5 2.9 2 1 0 2 2 2 0 AF0941-like LRR_9 PF14580.6 AIO00171.1 - 2.3e-17 63.1 0.3 3.5e-17 62.4 0.3 1.2 1 0 0 1 1 1 1 Leucine-rich repeat LRR_4 PF12799.7 AIO00171.1 - 5.2e-11 42.6 1.8 4.5e-05 23.7 0.4 3.7 1 1 4 5 5 5 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 AIO00171.1 - 1.1e-07 31.6 3.1 4.3e-07 29.6 0.4 2.9 3 1 0 3 3 3 1 Leucine rich repeat LRR_6 PF13516.6 AIO00171.1 - 0.0013 18.6 1.4 2.5 8.4 0.1 3.4 3 0 0 3 3 3 2 Leucine Rich repeat LRR_1 PF00560.33 AIO00171.1 - 0.88 10.4 4.2 1.4e+02 3.6 0.2 4.5 3 1 0 3 3 3 0 Leucine Rich Repeat Myosin_TH1 PF06017.13 AIO00172.1 - 0.085 12.5 0.0 0.14 11.9 0.0 1.2 1 0 0 1 1 1 0 Unconventional myosin tail, actin- and lipid-binding Serine_protease PF18405.1 AIO00173.1 - 0.0069 15.6 0.7 0.18 10.9 0.1 2.2 2 0 0 2 2 2 2 Gammaproteobacterial serine protease ApbA PF02558.16 AIO00173.1 - 0.088 12.4 0.0 0.22 11.2 0.0 1.8 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA NAD_Gly3P_dh_C PF07479.14 AIO00173.1 - 0.13 12.5 0.0 0.24 11.7 0.0 1.4 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus Peptidase_M1 PF01433.20 AIO00174.1 - 1.5e-63 214.3 0.1 2.4e-63 213.6 0.1 1.3 1 0 0 1 1 1 1 Peptidase family M1 domain ERAP1_C PF11838.8 AIO00174.1 - 3.5e-32 112.2 0.5 5.4e-32 111.6 0.5 1.3 1 0 0 1 1 1 1 ERAP1-like C-terminal domain Peptidase_M1_N PF17900.1 AIO00174.1 - 3.7e-25 89.2 0.0 1.3e-24 87.4 0.0 1.8 2 0 0 2 2 2 1 Peptidase M1 N-terminal domain ERM PF00769.19 AIO00175.1 - 0.0023 17.8 27.2 0.2 11.5 6.7 3.4 3 0 0 3 3 3 3 Ezrin/radixin/moesin family Tropomyosin PF00261.20 AIO00175.1 - 0.0039 16.6 4.7 0.0039 16.6 4.7 3.6 4 0 0 4 4 4 1 Tropomyosin DUF2968 PF11180.8 AIO00175.1 - 0.013 15.1 12.6 0.013 15.1 12.6 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF2968) Phage_GP20 PF06810.11 AIO00175.1 - 0.35 10.6 23.9 0.028 14.2 7.0 3.2 3 0 0 3 3 3 0 Phage minor structural protein GP20 Peptidase_M3_N PF08439.10 AIO00175.1 - 0.84 10.0 4.6 0.85 9.9 1.8 2.6 2 0 0 2 2 2 0 Oligopeptidase F Filament PF00038.21 AIO00175.1 - 0.98 8.9 28.7 0.77 9.3 5.8 3.4 3 0 0 3 3 3 0 Intermediate filament protein Leu_zip PF15294.6 AIO00175.1 - 0.99 8.9 25.6 0.064 12.8 2.1 3.2 3 0 0 3 3 3 0 Leucine zipper Lebercilin PF15619.6 AIO00175.1 - 1 9.0 31.2 0.76 9.4 7.2 3.4 3 0 0 3 3 3 0 Ciliary protein causing Leber congenital amaurosis disease Fez1 PF06818.15 AIO00175.1 - 1 9.8 24.9 0.39 11.1 1.7 3.4 3 0 0 3 3 3 0 Fez1 HIP1_clath_bdg PF16515.5 AIO00175.1 - 1.3 9.7 36.0 0.38 11.4 5.6 3.9 4 0 0 4 4 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 LMBR1 PF04791.16 AIO00175.1 - 1.3 7.9 7.0 0.42 9.5 3.2 1.9 2 0 0 2 2 2 0 LMBR1-like membrane protein DUF745 PF05335.13 AIO00175.1 - 2.2 8.0 39.3 1.2 8.9 12.2 4.5 4 0 0 4 4 4 0 Protein of unknown function (DUF745) APG6_N PF17675.1 AIO00175.1 - 2.4 8.7 47.4 2.1 8.9 13.8 4.2 4 0 0 4 4 4 0 Apg6 coiled-coil region Spc7 PF08317.11 AIO00175.1 - 3.7 6.4 26.6 0.6 8.9 1.6 3.4 3 0 0 3 3 3 0 Spc7 kinetochore protein betaPIX_CC PF16523.5 AIO00175.1 - 4.1 7.3 11.3 1.2 9.0 0.4 2.9 2 1 0 2 2 2 0 betaPIX coiled coil ADIP PF11559.8 AIO00175.1 - 4.7 7.3 40.7 0.92 9.6 6.3 3.7 4 0 0 4 4 3 0 Afadin- and alpha -actinin-Binding FlaC_arch PF05377.11 AIO00175.1 - 4.8 7.7 8.7 26 5.3 0.8 4.0 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) Fib_alpha PF08702.10 AIO00175.1 - 7.2 6.8 16.2 1 9.5 2.3 3.5 3 0 0 3 3 3 0 Fibrinogen alpha/beta chain family DUF3450 PF11932.8 AIO00175.1 - 7.8 5.7 30.9 0.19 11.0 7.6 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF3450) DUF1664 PF07889.12 AIO00175.1 - 7.9 6.5 17.2 0.52 10.4 2.1 4.5 5 0 0 5 5 5 0 Protein of unknown function (DUF1664) CHD5 PF04420.14 AIO00175.1 - 8 6.3 10.1 2.9 7.7 3.4 2.7 2 0 0 2 2 2 0 CHD5-like protein FlxA PF14282.6 AIO00175.1 - 8.6 6.4 29.8 18 5.4 0.3 4.2 3 1 0 3 3 3 0 FlxA-like protein SLD5_C PF16922.5 AIO00176.1 - 2.1e-07 31.0 0.0 3.4e-07 30.4 0.0 1.4 1 0 0 1 1 1 1 DNA replication complex GINS protein SLD5 C-terminus MraY_sig1 PF10555.9 AIO00176.1 - 0.021 14.3 2.1 0.052 13.1 2.1 1.7 1 0 0 1 1 1 0 Phospho-N-acetylmuramoyl-pentapeptide-transferase signature 1 Sld5 PF05916.11 AIO00176.1 - 0.039 14.4 0.1 0.095 13.2 0.0 1.7 2 0 0 2 2 2 0 GINS complex protein Acyltransferase PF01553.21 AIO00177.1 - 1.1e-11 44.5 0.0 2e-11 43.7 0.0 1.4 1 0 0 1 1 1 1 Acyltransferase UCH PF00443.29 AIO00179.1 - 1.8e-43 148.9 0.0 3e-43 148.2 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 AIO00179.1 - 1e-15 57.8 5.4 1e-15 57.8 5.4 3.8 4 0 0 4 4 4 1 Zn-finger in ubiquitin-hydrolases and other protein zf-UBP_var PF17807.1 AIO00179.1 - 2.6e-14 52.7 9.9 6.7e-13 48.2 8.3 2.7 2 0 0 2 2 2 1 Variant UBP zinc finger UCH_1 PF13423.6 AIO00179.1 - 8e-14 51.9 0.0 3.4e-13 49.9 0.0 2.0 2 1 1 3 3 3 1 Ubiquitin carboxyl-terminal hydrolase UBA PF00627.31 AIO00179.1 - 0.00026 20.8 0.1 0.00057 19.7 0.1 1.6 1 0 0 1 1 1 1 UBA/TS-N domain CUE PF02845.16 AIO00179.1 - 0.039 13.7 0.0 0.078 12.7 0.0 1.5 1 0 0 1 1 1 0 CUE domain UBA_4 PF14555.6 AIO00179.1 - 0.05 13.4 0.0 0.1 12.4 0.0 1.5 1 0 0 1 1 1 0 UBA-like domain ECH_1 PF00378.20 AIO00180.1 - 5.5e-73 245.4 0.7 6.3e-73 245.2 0.7 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 AIO00180.1 - 1.7e-36 126.4 1.3 1.5e-31 110.2 0.1 2.0 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase Peptidase_S49 PF01343.18 AIO00180.1 - 0.015 15.3 0.0 1.1 9.2 0.0 2.4 2 0 0 2 2 2 0 Peptidase family S49 Pkinase PF00069.25 AIO00181.1 - 3.1e-55 187.4 0.0 6e-55 186.4 0.0 1.4 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 AIO00181.1 - 3.8e-35 121.4 0.0 6.5e-35 120.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 AIO00181.1 - 1.7e-05 23.9 0.2 0.0045 16.0 0.0 2.9 3 0 0 3 3 3 1 Haspin like kinase domain Pkinase_fungal PF17667.1 AIO00181.1 - 2.3e-05 23.4 0.0 4.1e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 AIO00181.1 - 0.00031 20.7 0.0 0.087 12.7 0.0 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 AIO00181.1 - 0.016 14.2 0.0 0.047 12.7 0.0 1.7 2 0 0 2 2 2 0 Seadornavirus VP7 Pox_ser-thr_kin PF05445.11 AIO00181.1 - 0.019 14.0 0.1 0.028 13.4 0.1 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Pro-NT_NN PF07421.11 AIO00181.1 - 0.059 13.6 0.2 0.11 12.8 0.2 1.4 1 0 0 1 1 1 0 Neurotensin/neuromedin N precursor DUF1664 PF07889.12 AIO00182.1 - 0.03 14.4 4.4 0.37 10.8 0.1 3.6 3 1 1 4 4 4 0 Protein of unknown function (DUF1664) STAT_alpha PF01017.20 AIO00182.1 - 1.8 8.4 6.8 16 5.3 0.1 2.5 2 1 1 3 3 3 0 STAT protein, all-alpha domain NAP PF00956.18 AIO00183.1 - 6e-08 32.2 3.7 0.0037 16.5 0.0 3.0 1 1 2 3 3 3 3 Nucleosome assembly protein (NAP) Phage_Mu_Gam PF07352.12 AIO00183.1 - 0.043 13.7 0.0 0.058 13.3 0.0 1.2 1 0 0 1 1 1 0 Bacteriophage Mu Gam like protein COQ7 PF03232.13 AIO00184.1 - 2.4e-53 180.4 0.1 2.8e-53 180.2 0.1 1.0 1 0 0 1 1 1 1 Ubiquinone biosynthesis protein COQ7 Peptidase_M18 PF02127.15 AIO00185.1 - 1.2e-157 525.2 0.0 1.3e-157 525.0 0.0 1.0 1 0 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) Peptidase_M42 PF05343.14 AIO00185.1 - 8.3e-08 31.6 0.0 5.2e-05 22.4 0.1 2.2 1 1 0 2 2 2 2 M42 glutamyl aminopeptidase Ribosomal_L39 PF00832.20 AIO00186.1 - 3.4e-18 65.0 15.4 3.8e-18 64.8 15.4 1.0 1 0 0 1 1 1 1 Ribosomal L39 protein Kinesin PF00225.23 AIO00188.1 - 1.5e-92 310.1 0.1 1.8e-92 309.8 0.1 1.1 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 AIO00188.1 - 1.6e-19 70.3 0.0 3.5e-19 69.2 0.0 1.6 1 0 0 1 1 1 1 Microtubule binding C2 PF00168.30 AIO00188.1 - 0.0002 21.6 0.0 0.00049 20.3 0.0 1.7 1 0 0 1 1 1 1 C2 domain STN1_2 PF09170.10 AIO00188.1 - 0.061 13.5 0.5 0.15 12.2 0.5 1.6 1 0 0 1 1 1 0 CST, Suppressor of cdc thirteen homolog, complex subunit STN1 GAS PF13851.6 AIO00188.1 - 0.1 11.9 1.9 0.21 10.9 1.9 1.4 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding Caldesmon PF02029.15 AIO00188.1 - 0.18 10.5 3.7 0.59 8.8 3.7 1.6 1 1 0 1 1 1 0 Caldesmon NIF PF03031.18 AIO00189.1 - 6e-32 110.6 0.0 8.5e-32 110.1 0.0 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase DUF705 PF05152.12 AIO00189.1 - 0.0016 18.0 0.0 0.0026 17.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF705) Acyltransferase PF01553.21 AIO00190.1 - 1.2e-10 41.2 0.0 2.1e-10 40.3 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase JmjN PF02375.17 AIO00190.1 - 0.028 14.4 0.1 0.058 13.4 0.1 1.5 1 0 0 1 1 1 0 jmjN domain ECF_trnsprt PF12822.7 AIO00190.1 - 0.062 13.4 3.1 0.12 12.4 3.1 1.5 1 0 0 1 1 1 0 ECF transporter, substrate-specific component Caudo_TAP PF02413.17 AIO00192.1 - 0.096 12.8 0.0 0.23 11.6 0.0 1.6 1 0 0 1 1 1 0 Caudovirales tail fibre assembly protein, lambda gpK DUF1731 PF08338.11 AIO00192.1 - 0.1 12.5 0.0 0.26 11.2 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1731) PDEase_I PF00233.19 AIO00193.1 - 3.5e-74 249.5 1.8 9.1e-74 248.2 1.3 1.9 2 0 0 2 2 2 1 3'5'-cyclic nucleotide phosphodiesterase Astro_capsid_N PF03115.14 AIO00193.1 - 0.022 13.4 0.0 0.033 12.9 0.0 1.2 1 0 0 1 1 1 0 Astrovirus capsid protein precursor HSP20 PF00011.21 AIO00194.1 - 3e-17 62.6 0.0 3.6e-17 62.4 0.0 1.1 1 0 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 AIO00194.1 - 3.3e-10 39.4 0.0 5.2e-10 38.7 0.0 1.3 1 0 0 1 1 1 1 HSP20-like domain found in ArsA PapC_N PF13954.6 AIO00194.1 - 0.04 13.9 0.0 0.053 13.5 0.0 1.3 1 1 0 1 1 1 0 PapC N-terminal domain Ribosomal_L13e PF01294.18 AIO00195.1 - 3.7e-62 209.4 4.7 4.7e-62 209.0 4.7 1.1 1 0 0 1 1 1 1 Ribosomal protein L13e DUF4169 PF13770.6 AIO00195.1 - 0.062 13.6 0.3 0.062 13.6 0.3 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4169) PTPS PF01242.19 AIO00195.1 - 0.066 13.2 0.0 0.097 12.6 0.0 1.2 1 0 0 1 1 1 0 6-pyruvoyl tetrahydropterin synthase Pkinase PF00069.25 AIO00197.1 - 2.7e-42 145.0 0.0 3.9e-42 144.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 AIO00197.1 - 5.5e-35 120.9 0.0 6.9e-35 120.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 AIO00197.1 - 0.0042 16.1 0.2 0.0076 15.2 0.2 1.4 1 0 0 1 1 1 1 Haspin like kinase domain Pkinase_fungal PF17667.1 AIO00197.1 - 0.009 14.8 0.0 0.016 14.0 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase Pox_ser-thr_kin PF05445.11 AIO00197.1 - 0.055 12.4 0.1 0.096 11.6 0.1 1.3 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase APH PF01636.23 AIO00197.1 - 0.057 13.3 0.0 0.089 12.7 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family AAA PF00004.29 AIO00198.1 - 4.9e-40 137.0 0.0 1.2e-39 135.7 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.10 AIO00198.1 - 1e-24 86.3 0.1 2.6e-24 85.0 0.1 1.8 1 0 0 1 1 1 1 Vps4 C terminal oligomerisation domain MIT PF04212.18 AIO00198.1 - 1.7e-16 60.0 3.7 1.7e-16 60.0 3.7 2.1 2 0 0 2 2 1 1 MIT (microtubule interacting and transport) domain AAA_lid_3 PF17862.1 AIO00198.1 - 1.2e-08 34.6 0.3 4.4e-07 29.6 0.0 3.0 3 0 0 3 3 3 1 AAA+ lid domain AAA_2 PF07724.14 AIO00198.1 - 4e-06 27.1 0.0 1.1e-05 25.6 0.0 1.8 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 AIO00198.1 - 1.6e-05 25.4 0.1 0.00097 19.6 0.0 2.7 2 1 1 3 3 3 1 AAA ATPase domain AAA_22 PF13401.6 AIO00198.1 - 3.8e-05 24.0 0.5 0.0032 17.7 0.1 2.7 2 1 0 2 2 1 1 AAA domain AAA_5 PF07728.14 AIO00198.1 - 0.00011 22.2 0.0 0.00065 19.7 0.0 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 AIO00198.1 - 0.0005 19.8 0.0 0.0013 18.5 0.0 1.5 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain IstB_IS21 PF01695.17 AIO00198.1 - 0.00064 19.5 0.0 0.0013 18.5 0.0 1.6 1 1 0 1 1 1 1 IstB-like ATP binding protein AAA_24 PF13479.6 AIO00198.1 - 0.00098 18.9 0.0 0.0026 17.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 AIO00198.1 - 0.0011 19.1 0.0 0.0028 17.8 0.0 1.8 1 0 0 1 1 1 1 AAA domain DUF815 PF05673.13 AIO00198.1 - 0.0014 17.8 0.0 0.0025 17.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) TIP49 PF06068.13 AIO00198.1 - 0.0014 17.9 0.0 0.0023 17.2 0.0 1.3 1 0 0 1 1 1 1 TIP49 P-loop domain USP8_dimer PF08969.11 AIO00198.1 - 0.0019 18.4 3.3 0.0049 17.0 3.3 1.6 1 0 0 1 1 1 1 USP8 dimerisation domain AAA_14 PF13173.6 AIO00198.1 - 0.0023 18.0 0.0 0.0089 16.1 0.0 1.9 2 1 0 2 2 2 1 AAA domain AAA_18 PF13238.6 AIO00198.1 - 0.0043 17.6 0.0 0.018 15.6 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_25 PF13481.6 AIO00198.1 - 0.0075 15.9 0.4 0.82 9.2 0.1 2.4 1 1 1 2 2 2 1 AAA domain RNA_helicase PF00910.22 AIO00198.1 - 0.0093 16.3 0.0 0.024 15.0 0.0 1.7 1 0 0 1 1 1 1 RNA helicase ATPase_2 PF01637.18 AIO00198.1 - 0.015 15.3 2.8 2.8 7.8 0.0 3.0 2 2 1 3 3 3 0 ATPase domain predominantly from Archaea Viral_helicase1 PF01443.18 AIO00198.1 - 0.034 13.9 0.0 0.059 13.1 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_17 PF13207.6 AIO00198.1 - 0.035 14.5 0.0 0.11 12.9 0.0 2.0 2 0 0 2 2 1 0 AAA domain Mg_chelatase PF01078.21 AIO00198.1 - 0.048 13.0 0.0 0.099 12.0 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI PPV_E1_C PF00519.17 AIO00198.1 - 0.051 12.4 0.0 0.073 11.9 0.0 1.2 1 0 0 1 1 1 0 Papillomavirus helicase CPT PF07931.12 AIO00198.1 - 0.053 13.4 0.0 0.16 11.8 0.0 1.9 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein Parvo_NS1 PF01057.17 AIO00198.1 - 0.07 12.2 0.0 0.14 11.2 0.0 1.4 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 NACHT PF05729.12 AIO00198.1 - 0.084 12.8 0.0 0.7 9.8 0.0 2.2 1 1 0 2 2 2 0 NACHT domain AAA_7 PF12775.7 AIO00198.1 - 0.09 12.3 0.0 0.29 10.6 0.0 1.8 2 1 0 2 2 2 0 P-loop containing dynein motor region AFG1_ATPase PF03969.16 AIO00198.1 - 0.11 11.4 0.0 0.15 10.9 0.0 1.2 1 0 0 1 1 1 0 AFG1-like ATPase PhoH PF02562.16 AIO00198.1 - 0.14 11.6 0.2 0.32 10.4 0.2 1.5 1 0 0 1 1 1 0 PhoH-like protein PFK PF00365.20 AIO00199.1 - 2.7e-63 214.0 0.5 3.4e-63 213.6 0.5 1.1 1 0 0 1 1 1 1 Phosphofructokinase DAGK_cat PF00781.24 AIO00199.1 - 0.00041 20.0 0.2 0.00097 18.8 0.0 1.7 2 0 0 2 2 2 1 Diacylglycerol kinase catalytic domain NAD_kinase PF01513.21 AIO00199.1 - 0.036 13.3 0.0 0.052 12.8 0.0 1.3 1 0 0 1 1 1 0 ATP-NAD kinase zf-MIZ PF02891.20 AIO00200.1 - 6.8e-09 35.3 0.3 2.5e-08 33.6 0.0 2.1 2 0 0 2 2 2 1 MIZ/SP-RING zinc finger Methyltr_RsmB-F PF01189.17 AIO00202.1 - 1.5e-38 132.5 0.1 9.1e-37 126.6 0.1 2.3 1 1 0 1 1 1 1 16S rRNA methyltransferase RsmB/F FtsJ PF01728.19 AIO00202.1 - 2.5e-05 24.4 0.0 6.5e-05 23.1 0.0 1.7 1 1 0 1 1 1 1 FtsJ-like methyltransferase Bombolitin PF08096.11 AIO00202.1 - 0.38 11.1 1.3 0.85 10.0 1.3 1.6 1 0 0 1 1 1 0 Bombolitin family TPR_19 PF14559.6 AIO00203.1 - 1.1e-22 80.2 20.6 3.7e-05 24.1 2.4 8.8 7 2 2 9 9 9 7 Tetratricopeptide repeat TPR_14 PF13428.6 AIO00203.1 - 3.3e-13 49.2 39.9 0.00083 20.0 0.2 10.8 9 2 3 12 12 10 5 Tetratricopeptide repeat TPR_16 PF13432.6 AIO00203.1 - 1.2e-09 38.7 31.4 0.039 14.6 2.3 8.3 6 2 3 9 9 9 5 Tetratricopeptide repeat TPR_2 PF07719.17 AIO00203.1 - 4.6e-09 35.7 22.5 0.16 12.1 0.0 11.4 12 0 0 12 12 12 1 Tetratricopeptide repeat HrpB1_HrpK PF09613.10 AIO00203.1 - 1.7e-08 34.2 19.8 0.00094 18.8 1.8 5.8 6 1 1 7 7 7 2 Bacterial type III secretion protein (HrpB1_HrpK) ANAPC3 PF12895.7 AIO00203.1 - 2.3e-07 30.9 13.7 0.27 11.5 0.4 5.8 6 0 0 6 6 6 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_1 PF00515.28 AIO00203.1 - 1.9e-05 24.3 3.3 0.65 9.9 0.0 6.7 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_12 PF13424.6 AIO00203.1 - 9.4e-05 22.6 34.4 0.45 10.8 2.9 9.7 9 2 1 10 10 10 2 Tetratricopeptide repeat TPR_4 PF07721.14 AIO00203.1 - 0.0039 17.7 38.5 0.35 11.6 0.7 10.1 9 0 0 9 9 8 1 Tetratricopeptide repeat TPR_6 PF13174.6 AIO00203.1 - 0.0041 17.7 19.4 0.17 12.6 0.0 8.7 10 0 0 10 10 9 1 Tetratricopeptide repeat TPR_17 PF13431.6 AIO00203.1 - 0.0052 17.1 14.2 67 4.2 0.0 8.2 9 0 0 9 9 8 0 Tetratricopeptide repeat TPR_20 PF14561.6 AIO00203.1 - 0.0082 16.5 7.0 0.028 14.8 0.4 4.1 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_11 PF13414.6 AIO00203.1 - 0.016 14.9 6.8 1.2 8.8 0.0 5.2 6 0 0 6 6 6 0 TPR repeat NatB_MDM20 PF09797.9 AIO00203.1 - 0.025 13.5 0.2 0.025 13.5 0.2 2.5 3 0 0 3 3 3 0 N-acetyltransferase B complex (NatB) non catalytic subunit Topoisom_bac PF01131.20 AIO00203.1 - 0.051 12.6 0.1 0.099 11.6 0.1 1.4 1 0 0 1 1 1 0 DNA topoisomerase Fis1_TPR_C PF14853.6 AIO00203.1 - 0.088 12.9 2.0 17 5.6 0.0 4.5 6 0 0 6 6 5 0 Fis1 C-terminal tetratricopeptide repeat Coatomer_E PF04733.14 AIO00203.1 - 0.35 10.3 8.5 18 4.7 0.5 5.1 5 2 2 7 7 7 0 Coatomer epsilon subunit TPR_9 PF13371.6 AIO00203.1 - 0.84 9.8 16.1 9.6 6.4 0.4 5.6 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_7 PF13176.6 AIO00203.1 - 2.3 8.5 10.3 53 4.2 0.0 6.4 8 0 0 8 8 7 0 Tetratricopeptide repeat DUF4586 PF15239.6 AIO00204.1 - 3.7e-67 227.7 10.7 4.4e-67 227.4 10.7 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4586) Pkinase PF00069.25 AIO00205.1 - 1e-65 221.8 0.0 1.6e-65 221.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 AIO00205.1 - 6.5e-45 153.4 0.0 1.7e-44 152.1 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 AIO00205.1 - 9.1e-06 25.2 0.1 1.8e-05 24.2 0.0 1.5 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 AIO00205.1 - 0.0071 16.3 0.9 1.7 8.5 0.0 2.6 2 1 1 3 3 3 2 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 AIO00205.1 - 0.026 13.3 0.1 0.072 11.8 0.0 1.7 2 0 0 2 2 2 0 Fungal protein kinase Ribos_L4_asso_C PF14374.6 AIO00205.1 - 0.027 14.5 0.2 0.083 13.0 0.2 1.9 1 0 0 1 1 1 0 60S ribosomal protein L4 C-terminal domain KHA PF11834.8 AIO00207.1 - 0.011 15.8 0.0 2.1 8.5 0.0 2.6 2 0 0 2 2 2 0 KHA, dimerisation domain of potassium ion channel PAP_central PF04928.17 AIO00208.1 - 5.6e-36 123.8 0.0 7.7e-36 123.3 0.0 1.1 1 0 0 1 1 1 1 Poly(A) polymerase central domain PAP_RNA-bind PF04926.15 AIO00208.1 - 2.3e-06 27.4 0.0 4.1e-06 26.6 0.0 1.3 1 0 0 1 1 1 1 Poly(A) polymerase predicted RNA binding domain NTP_transf_2 PF01909.23 AIO00208.1 - 6.7e-05 23.1 0.0 0.00012 22.3 0.0 1.4 1 0 0 1 1 1 1 Nucleotidyltransferase domain Polbeta PF18765.1 AIO00208.1 - 0.0023 18.0 0.0 0.0046 17.0 0.0 1.4 1 0 0 1 1 1 1 Polymerase beta, Nucleotidyltransferase Mei5 PF10376.9 AIO00209.1 - 0.021 14.7 4.6 0.022 14.6 1.9 2.3 3 0 0 3 3 3 0 Double-strand recombination repair protein FlaC_arch PF05377.11 AIO00209.1 - 0.24 11.8 5.0 52 4.3 0.2 5.0 5 0 0 5 5 5 0 Flagella accessory protein C (FlaC) DUF4600 PF15372.6 AIO00209.1 - 0.4 11.1 4.0 0.33 11.4 1.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4600) Noelin-1 PF12308.8 AIO00209.1 - 0.5 10.4 3.8 1.1 9.3 2.2 2.5 2 0 0 2 2 2 0 Neurogenesis glycoprotein Lectin_N PF03954.14 AIO00209.1 - 0.81 9.4 9.6 0.064 13.0 0.8 3.4 4 0 0 4 4 4 0 Hepatic lectin, N-terminal domain KASH_CCD PF14662.6 AIO00209.1 - 0.83 9.4 12.8 0.22 11.3 6.7 2.8 3 0 0 3 3 3 0 Coiled-coil region of CCDC155 or KASH GAS PF13851.6 AIO00209.1 - 2.9 7.2 14.9 0.033 13.5 5.9 2.4 3 0 0 3 3 3 0 Growth-arrest specific micro-tubule binding SAM_1 PF00536.30 AIO00211.1 - 3.6e-05 24.1 0.0 9.5e-05 22.8 0.0 1.8 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_PNT PF02198.16 AIO00211.1 - 0.03 14.3 0.0 0.07 13.1 0.0 1.6 1 0 0 1 1 1 0 Sterile alpha motif (SAM)/Pointed domain SAM_2 PF07647.17 AIO00211.1 - 0.046 13.8 0.0 0.13 12.4 0.0 1.8 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) DUF1804 PF08822.11 AIO00211.1 - 0.24 11.4 1.8 3.7 7.5 0.8 3.0 2 1 0 2 2 2 0 Protein of unknown function (DUF1804) Arm PF00514.23 AIO00212.1 - 0.0036 17.3 4.5 0.65 10.1 0.1 3.9 4 0 0 4 4 4 2 Armadillo/beta-catenin-like repeat Scaffolding_pro PF11418.8 AIO00212.1 - 0.091 13.3 0.0 0.19 12.3 0.0 1.5 1 0 0 1 1 1 0 Phi29 scaffolding protein Cnd3 PF12719.7 AIO00213.1 - 2.3e-37 128.8 0.7 2.3e-37 128.8 0.7 2.0 2 0 0 2 2 2 1 Nuclear condensing complex subunits, C-term domain HEAT_2 PF13646.6 AIO00213.1 - 1e-08 35.4 10.7 0.00011 22.5 0.7 6.1 5 1 2 7 7 7 3 HEAT repeats Cnd1 PF12717.7 AIO00213.1 - 3.2e-08 33.8 0.3 0.046 13.8 0.2 4.5 3 1 2 5 5 5 2 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 AIO00213.1 - 8.2e-05 22.5 12.3 1.8 9.0 0.0 6.5 6 0 0 6 6 6 3 HEAT repeat SspB PF04386.13 AIO00213.1 - 0.043 13.7 0.2 12 5.8 0.0 2.8 3 0 0 3 3 3 0 Stringent starvation protein B RTP1_C1 PF10363.9 AIO00213.1 - 0.055 13.7 0.1 2.3 8.4 0.0 3.2 2 0 0 2 2 2 0 Required for nuclear transport of RNA pol II C-terminus 1 Helicase_C_2 PF13307.6 AIO00214.1 - 1e-48 165.7 0.0 3e-48 164.2 0.0 1.8 1 0 0 1 1 1 1 Helicase C-terminal domain DEAD_2 PF06733.15 AIO00214.1 - 2.2e-44 151.2 0.3 2.2e-43 147.9 0.0 2.2 2 0 0 2 2 2 1 DEAD_2 DEAD PF00270.29 AIO00214.1 - 1.2e-05 25.1 0.1 0.0015 18.3 0.0 2.4 1 1 1 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.15 AIO00214.1 - 7.9e-05 22.7 0.0 0.0021 18.1 0.0 2.3 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit HBB PF06777.11 AIO00214.1 - 0.0031 17.2 0.0 0.0083 15.8 0.0 1.7 1 0 0 1 1 1 1 Helical and beta-bridge domain AAA_11 PF13086.6 AIO00214.1 - 0.056 13.2 0.4 0.19 11.5 0.1 2.0 2 0 0 2 2 2 0 AAA domain Pkinase PF00069.25 AIO00215.1 - 3.6e-62 210.1 0.0 5e-62 209.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 AIO00215.1 - 5.1e-40 137.4 0.0 7.3e-40 136.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 AIO00215.1 - 0.00029 20.9 0.1 0.084 12.8 0.0 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 AIO00215.1 - 0.00041 19.2 0.0 0.00041 19.2 0.0 2.3 3 0 0 3 3 3 1 Fungal protein kinase Kinase-like PF14531.6 AIO00215.1 - 0.00091 18.6 0.0 0.0024 17.2 0.0 1.7 2 0 0 2 2 2 1 Kinase-like FTA2 PF13095.6 AIO00215.1 - 0.034 13.8 0.0 1.1 8.8 0.0 2.2 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Haspin_kinase PF12330.8 AIO00215.1 - 0.13 11.2 0.2 14 4.5 0.0 2.2 2 0 0 2 2 2 0 Haspin like kinase domain PDEase_I PF00233.19 AIO00216.1 - 1.6e-47 162.3 0.8 3.9e-47 161.0 0.0 2.1 2 1 0 2 2 2 1 3'5'-cyclic nucleotide phosphodiesterase FYVE PF01363.21 AIO00216.1 - 1.3e-07 31.7 13.3 2.6e-07 30.6 13.3 1.5 1 0 0 1 1 1 1 FYVE zinc finger Glu-tRNAGln PF02686.15 AIO00216.1 - 0.0095 16.2 0.5 0.0095 16.2 0.5 3.6 4 0 0 4 4 4 1 Glu-tRNAGln amidotransferase C subunit Esterase_phd PF10503.9 AIO00217.1 - 3.5 7.0 8.5 0.31 10.5 2.6 2.0 2 0 0 2 2 2 0 Esterase PHB depolymerase Beta_helix PF13229.6 AIO00219.1 - 4.6e-29 101.3 3.7 3.9e-15 56.0 0.1 2.1 1 1 1 2 2 2 2 Right handed beta helix region NosD PF05048.13 AIO00219.1 - 3.3e-09 36.4 0.0 4.4e-09 36.0 0.0 1.3 1 0 0 1 1 1 1 Periplasmic copper-binding protein (NosD) Pkinase PF00069.25 AIO00220.1 - 2.5e-36 125.4 0.0 3.7e-35 121.6 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 AIO00220.1 - 6.1e-15 55.2 0.0 1.2e-14 54.2 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 AIO00220.1 - 0.00027 20.3 0.0 0.00052 19.4 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family START PF01852.19 AIO00221.1 - 5.4e-28 97.8 0.0 9e-28 97.1 0.0 1.2 1 0 0 1 1 1 1 START domain DUF3074 PF11274.8 AIO00221.1 - 0.0017 18.4 0.0 0.011 15.7 0.0 2.1 1 1 0 1 1 1 1 Protein of unknown function (DUF3074) Actin PF00022.19 AIO00222.1 - 2.1e-19 69.4 0.0 4.1e-13 48.7 0.0 2.4 1 1 0 2 2 2 2 Actin Ins_beta PF03488.14 AIO00223.1 - 0.037 14.0 0.5 0.064 13.3 0.5 1.4 1 0 0 1 1 1 0 Nematode insulin-related peptide beta type TPR_19 PF14559.6 AIO00224.1 - 4.2e-10 40.0 2.1 0.0071 16.8 0.1 4.7 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_2 PF07719.17 AIO00224.1 - 3.5e-08 32.9 21.7 0.036 14.2 0.2 6.8 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_16 PF13432.6 AIO00224.1 - 4.8e-08 33.5 1.9 0.068 13.8 0.0 4.3 3 1 1 4 4 4 3 Tetratricopeptide repeat ANAPC3 PF12895.7 AIO00224.1 - 6.4e-06 26.3 16.5 0.032 14.5 0.7 5.0 4 1 0 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_1 PF00515.28 AIO00224.1 - 0.00023 20.8 16.1 0.15 11.9 0.3 5.1 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_12 PF13424.6 AIO00224.1 - 0.00047 20.4 9.5 0.78 10.1 0.2 5.3 4 2 0 4 4 4 1 Tetratricopeptide repeat TPR_14 PF13428.6 AIO00224.1 - 0.00075 20.1 4.8 10 7.3 0.0 5.2 6 0 0 6 6 4 1 Tetratricopeptide repeat TPR_11 PF13414.6 AIO00224.1 - 0.00099 18.7 1.6 0.2 11.4 0.1 2.9 2 0 0 2 2 2 2 TPR repeat DUF4993 PF16384.5 AIO00224.1 - 0.0083 15.2 0.1 0.015 14.3 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function TPR_7 PF13176.6 AIO00224.1 - 0.05 13.7 1.6 2.3 8.4 0.0 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_3 PF07720.12 AIO00224.1 - 0.6 10.2 14.2 1.1 9.3 0.2 5.2 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_8 PF13181.6 AIO00224.1 - 1.5 9.2 13.3 21 5.7 0.1 5.8 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_6 PF13174.6 AIO00224.1 - 7.3 7.5 10.5 13 6.7 0.0 5.5 6 0 0 6 6 6 0 Tetratricopeptide repeat Trypsin_2 PF13365.6 AIO00225.1 - 0.017 16.0 4.4 0.044 14.7 4.4 1.6 1 1 0 1 1 1 0 Trypsin-like peptidase domain Mito_carr PF00153.27 AIO00226.1 - 5e-58 193.0 0.4 1.4e-19 69.8 0.0 3.1 2 1 1 3 3 3 3 Mitochondrial carrier protein ThrE_2 PF12821.7 AIO00226.1 - 0.0061 16.7 0.3 0.91 9.7 0.1 2.4 2 0 0 2 2 2 2 Threonine/Serine exporter, ThrE Peptidase_M57 PF12388.8 AIO00226.1 - 0.19 11.3 0.3 5.7 6.5 0.0 2.3 2 0 0 2 2 2 0 Dual-action HEIGH metallo-peptidase IU_nuc_hydro PF01156.19 AIO00228.1 - 1.2e-42 146.5 0.2 1.6e-42 146.1 0.2 1.1 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase LRR_6 PF13516.6 AIO00229.1 - 2.2e-28 95.8 32.1 0.0032 17.4 0.6 14.0 14 0 0 14 14 14 7 Leucine Rich repeat LRR_1 PF00560.33 AIO00229.1 - 1.4e-09 37.2 1.2 34 5.5 0.0 9.8 10 0 0 10 10 10 0 Leucine Rich Repeat LRR_4 PF12799.7 AIO00229.1 - 4e-06 27.1 14.4 1.9 9.0 0.1 6.8 6 1 1 7 7 7 1 Leucine Rich repeats (2 copies) DUF489 PF04356.12 AIO00229.1 - 0.0046 17.0 0.8 0.011 15.7 0.8 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF489) AAA_13 PF13166.6 AIO00229.1 - 0.069 11.8 9.9 0.098 11.3 9.9 1.1 1 0 0 1 1 1 0 AAA domain LRR_8 PF13855.6 AIO00229.1 - 0.15 11.8 23.6 2 8.2 0.9 7.5 6 5 0 6 6 6 0 Leucine rich repeat DUF3450 PF11932.8 AIO00229.1 - 0.73 9.1 13.1 3.4 6.9 6.5 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) PIEZO PF15917.5 AIO00229.1 - 1 8.8 5.1 2.1 7.7 5.1 1.4 1 0 0 1 1 1 0 Piezo Prominin PF05478.11 AIO00229.1 - 1.6 6.5 5.3 2.5 5.9 5.3 1.2 1 0 0 1 1 1 0 Prominin Occludin_ELL PF07303.13 AIO00229.1 - 2.2 9.1 5.2 3.1 8.6 3.4 2.1 1 1 0 1 1 1 0 Occludin homology domain DUF4407 PF14362.6 AIO00229.1 - 2.7 7.3 12.0 5.7 6.2 11.8 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) DUF1664 PF07889.12 AIO00229.1 - 5.1 7.2 7.2 11 6.1 1.9 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Fib_alpha PF08702.10 AIO00229.1 - 8.8 6.5 6.9 9.4 6.4 5.3 1.8 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family RRM_1 PF00076.22 AIO00231.1 - 2.4e-18 65.7 0.0 3.5e-18 65.2 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 AIO00231.1 - 0.055 13.1 0.0 0.096 12.3 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Metaviral_G PF09595.10 AIO00231.1 - 0.12 12.4 5.2 0.1 12.6 3.8 1.5 2 0 0 2 2 2 0 Metaviral_G glycoprotein Ribosomal_S19e PF01090.19 AIO00234.1 - 2.7e-43 146.9 0.0 3.2e-43 146.7 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S19e Mrr_N PF14338.6 AIO00234.1 - 0.0087 16.2 0.0 0.015 15.4 0.0 1.4 1 0 0 1 1 1 1 Mrr N-terminal domain LRR_4 PF12799.7 AIO00236.1 - 5.4e-18 64.8 0.0 0.12 12.8 0.1 9.3 5 4 5 11 11 11 6 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 AIO00236.1 - 0.0012 18.6 7.2 6.8 6.5 0.0 6.3 7 0 0 7 7 7 2 Leucine rich repeat LRR_1 PF00560.33 AIO00236.1 - 0.0027 18.0 4.1 2.1 9.2 0.1 6.1 6 1 0 6 6 6 1 Leucine Rich Repeat LRR_6 PF13516.6 AIO00236.1 - 0.0066 16.4 6.1 17 5.8 0.0 6.7 7 0 0 7 7 7 1 Leucine Rich repeat Colipase PF01114.18 AIO00236.1 - 0.14 11.8 1.5 0.6 9.8 1.5 2.1 1 0 0 1 1 1 0 Colipase, N-terminal domain Hydrolase_4 PF12146.8 AIO00238.1 - 2.3e-07 30.3 0.0 3e-06 26.7 0.0 2.0 1 1 1 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 AIO00238.1 - 1.4e-06 29.0 2.3 1.4e-06 29.0 2.3 1.7 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 AIO00238.1 - 2e-06 27.6 0.2 0.00011 22.0 0.2 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Pro_isomerase PF00160.21 AIO00239.1 - 1.1e-19 71.3 0.0 9e-19 68.3 0.0 2.0 1 1 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD UPF0220 PF05255.11 AIO00241.1 - 9.6e-18 64.3 0.1 1.2e-17 63.9 0.1 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0220) DUF3267 PF11667.8 AIO00241.1 - 0.013 15.8 0.4 0.028 14.7 0.1 1.8 1 1 1 2 2 2 0 Putative zincin peptidase EamA PF00892.20 AIO00241.1 - 0.013 15.6 3.5 0.019 15.1 3.5 1.3 1 0 0 1 1 1 0 EamA-like transporter family COPI_assoc PF08507.10 AIO00241.1 - 1.6 8.8 6.9 6.1 6.9 6.9 1.8 1 1 0 1 1 1 0 COPI associated protein MATH PF00917.26 AIO00242.1 - 6.7e-07 29.5 0.5 2.2e-06 27.8 0.5 2.0 1 0 0 1 1 1 1 MATH domain CorA PF01544.18 AIO00242.1 - 0.46 9.7 12.9 1.1 8.5 12.9 1.6 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein REF PF05755.12 AIO00242.1 - 6.1 6.6 9.2 28 4.4 9.2 2.1 1 1 0 1 1 1 0 Rubber elongation factor protein (REF) SHR3_chaperone PF08229.11 AIO00243.1 - 0.23 10.4 0.0 0.39 9.7 0.0 1.3 1 0 0 1 1 1 0 ER membrane protein SH3 COX1 PF00115.20 AIO00244.1 - 0.0039 16.1 0.7 0.0048 15.8 0.7 1.1 1 0 0 1 1 1 1 Cytochrome C and Quinol oxidase polypeptide I Cyclin_N PF00134.23 AIO00245.1 - 6.4e-24 84.1 0.4 2.1e-23 82.5 0.1 2.0 2 0 0 2 2 2 1 Cyclin, N-terminal domain TERF2_RBM PF16772.5 AIO00245.1 - 0.0098 15.3 0.0 0.026 13.9 0.0 1.7 1 0 0 1 1 1 1 Telomeric repeat-binding factor 2 Rap1-binding motif FoP_duplication PF13865.6 AIO00246.1 - 6.2e-05 23.5 8.2 6.2e-05 23.5 8.2 4.2 2 1 2 4 4 4 1 C-terminal duplication domain of Friend of PRMT1 LRR_4 PF12799.7 AIO00248.1 - 4e-10 39.8 9.9 0.0025 18.2 0.1 4.8 4 1 1 5 5 5 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 AIO00248.1 - 0.0015 18.3 16.9 0.1 12.4 0.1 5.3 6 0 0 6 6 6 2 Leucine rich repeat LRR_1 PF00560.33 AIO00248.1 - 0.0082 16.6 5.1 26 5.9 0.0 5.3 4 2 0 4 4 4 1 Leucine Rich Repeat LRR_6 PF13516.6 AIO00248.1 - 0.24 11.5 12.6 29 5.1 0.1 5.7 6 0 0 6 6 6 0 Leucine Rich repeat FAD-oxidase_C PF02913.19 AIO00249.1 - 2.5e-49 168.1 0.0 8.6e-49 166.4 0.0 1.8 2 0 0 2 2 2 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 AIO00249.1 - 6.5e-38 129.6 0.0 1.3e-37 128.6 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain tRNA-synt_2 PF00152.20 AIO00250.1 - 1.5e-77 260.8 0.0 1.9e-77 260.4 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA-synt_2d PF01409.20 AIO00250.1 - 5e-07 29.5 0.2 0.00029 20.4 0.1 2.3 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) tRNA_anti-codon PF01336.25 AIO00250.1 - 5.1e-07 29.6 0.0 9.5e-07 28.7 0.0 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain Yip1 PF04893.17 AIO00251.1 - 6.5e-11 42.3 14.9 1.2e-10 41.4 14.7 1.5 1 1 0 1 1 1 1 Yip1 domain LRR_6 PF13516.6 AIO00252.1 - 7.7e-43 140.9 14.0 1.6e-06 27.7 0.2 9.4 9 0 0 9 9 9 8 Leucine Rich repeat LRR_4 PF12799.7 AIO00252.1 - 3.4e-11 43.2 8.9 0.00042 20.6 0.2 5.7 3 2 3 6 6 6 5 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 AIO00252.1 - 2.1e-06 27.5 3.6 1.6 9.6 0.0 7.0 8 0 0 8 8 8 2 Leucine Rich Repeat LRR_8 PF13855.6 AIO00252.1 - 5.3e-06 26.1 14.0 0.37 10.6 3.0 6.6 4 3 1 5 5 5 3 Leucine rich repeat Rubis-subs-bind PF09273.11 AIO00253.1 - 1.3e-12 48.5 0.0 3.2e-12 47.3 0.0 1.7 1 0 0 1 1 1 1 Rubisco LSMT substrate-binding SET PF00856.28 AIO00253.1 - 0.0053 17.1 0.0 0.011 16.2 0.0 1.6 1 0 0 1 1 1 1 SET domain NAD_binding_2 PF03446.15 AIO00254.1 - 2.7e-51 173.9 1.0 4.9e-51 173.0 1.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 AIO00254.1 - 2.1e-36 124.9 0.1 3.4e-36 124.2 0.1 1.4 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 2-Hacid_dh_C PF02826.19 AIO00254.1 - 0.00054 19.4 0.0 0.0013 18.1 0.0 1.6 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain F420_oxidored PF03807.17 AIO00254.1 - 0.00088 19.8 0.9 0.0038 17.8 0.1 2.5 3 0 0 3 3 3 1 NADP oxidoreductase coenzyme F420-dependent 3HCDH_N PF02737.18 AIO00254.1 - 0.0051 16.7 0.1 0.012 15.6 0.1 1.7 1 1 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.14 AIO00254.1 - 0.017 14.7 0.1 3.1 7.3 0.0 2.3 1 1 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Shikimate_DH PF01488.20 AIO00254.1 - 0.018 15.1 0.0 0.037 14.1 0.0 1.6 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase PDH PF02153.17 AIO00254.1 - 0.04 12.9 0.0 0.059 12.4 0.0 1.3 1 0 0 1 1 1 0 Prephenate dehydrogenase IlvN PF07991.12 AIO00254.1 - 0.041 13.5 0.2 0.11 12.1 0.0 1.7 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain ApbA PF02558.16 AIO00254.1 - 0.066 12.8 0.0 0.12 12.0 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Nrf1_activ_bdg PF10492.9 AIO00254.1 - 0.12 13.1 1.0 39 5.0 0.0 3.0 3 0 0 3 3 3 0 Nrf1 activator activation site binding domain Gly-zipper_Omp PF13488.6 AIO00256.1 - 0.27 11.3 7.1 0.45 10.6 7.1 1.4 1 0 0 1 1 1 0 Glycine zipper RrnaAD PF00398.20 AIO00257.1 - 3.1e-61 206.8 0.0 4.1e-61 206.4 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_25 PF13649.6 AIO00257.1 - 9.4e-08 32.7 0.0 1.7e-07 31.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 AIO00257.1 - 2.9e-05 24.6 0.0 5.4e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 AIO00257.1 - 0.0013 19.4 0.0 0.0025 18.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 AIO00257.1 - 0.0015 18.3 0.0 0.0025 17.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 AIO00257.1 - 0.018 14.8 0.0 0.028 14.2 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_2 PF00891.18 AIO00257.1 - 0.033 13.5 0.0 0.055 12.8 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase domain Methyltransf_31 PF13847.6 AIO00257.1 - 0.041 13.7 0.0 0.063 13.1 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain DREV PF05219.12 AIO00257.1 - 0.047 12.8 0.0 0.084 11.9 0.0 1.3 1 0 0 1 1 1 0 DREV methyltransferase Methyltransf_28 PF02636.17 AIO00257.1 - 0.05 13.2 0.0 0.084 12.5 0.0 1.3 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase MTS PF05175.14 AIO00257.1 - 0.07 12.7 0.0 0.13 11.8 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_32 PF13679.6 AIO00257.1 - 0.086 12.8 0.0 0.15 12.1 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_18 PF12847.7 AIO00257.1 - 0.11 12.4 0.0 0.18 11.8 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Ubie_methyltran PF01209.18 AIO00257.1 - 0.13 11.6 0.0 0.23 10.8 0.0 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family zf-RanBP PF00641.18 AIO00258.1 - 0.0039 16.5 5.9 0.0039 16.5 5.9 1.8 2 0 0 2 2 2 1 Zn-finger in Ran binding protein and others Mito_carr PF00153.27 AIO00259.1 - 2.9e-11 43.2 0.1 2.5e-06 27.3 0.0 2.4 2 0 0 2 2 2 2 Mitochondrial carrier protein Rhv PF00073.20 AIO00260.1 - 0.13 11.9 0.1 0.24 11.0 0.1 1.3 1 0 0 1 1 1 0 picornavirus capsid protein RNase_T PF00929.24 AIO00261.1 - 1.4e-16 61.5 0.0 3.2e-16 60.3 0.0 1.7 1 0 0 1 1 1 1 Exonuclease UCH_1 PF13423.6 AIO00261.1 - 9.1e-14 51.8 0.0 4.1e-11 43.1 0.0 2.3 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase UCH PF00443.29 AIO00261.1 - 7e-05 22.4 0.0 0.00018 21.1 0.0 1.7 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase PCuAC PF04314.13 AIO00261.1 - 0.017 14.9 0.0 0.045 13.5 0.0 1.6 1 0 0 1 1 1 0 Copper chaperone PCu(A)C zf-C2H2_4 PF13894.6 AIO00262.1 - 1.5e-15 56.6 52.0 0.013 16.3 0.6 8.4 8 0 0 8 8 8 6 C2H2-type zinc finger zf-C2H2 PF00096.26 AIO00262.1 - 9.7e-12 44.7 49.7 0.0037 17.6 0.2 8.4 8 0 0 8 8 8 4 Zinc finger, C2H2 type zf-Di19 PF05605.12 AIO00262.1 - 5.3e-11 42.6 31.4 0.0033 17.7 1.2 7.1 7 0 0 7 7 7 4 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_jaz PF12171.8 AIO00262.1 - 3.7e-07 30.3 22.8 0.045 14.0 0.2 6.2 6 1 0 6 6 6 4 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 AIO00262.1 - 7e-05 23.1 15.2 0.33 11.4 0.6 5.8 6 0 0 6 6 5 3 Zinc-finger of C2H2 type Actin_micro PF17003.5 AIO00262.1 - 0.00022 20.5 4.7 5.7 6.0 0.1 5.2 5 1 0 5 5 5 1 Putative actin-like family DUF629 PF04780.12 AIO00262.1 - 0.00036 19.2 9.7 6.5 5.2 1.0 5.6 5 1 1 6 6 6 0 Protein of unknown function (DUF629) zf_C2H2_10 PF18414.1 AIO00262.1 - 0.00081 18.9 10.0 0.022 14.3 0.1 3.9 4 0 0 4 4 4 2 C2H2 type zinc-finger TRAF6_Z2 PF18048.1 AIO00262.1 - 0.0012 18.9 4.9 0.28 11.3 0.1 4.3 4 0 0 4 4 4 1 TNF receptor-associated factor 6 zinc finger 2 FOXP-CC PF16159.5 AIO00262.1 - 0.0081 16.8 24.5 36 5.1 2.5 7.8 6 2 2 8 8 8 0 FOXP coiled-coil domain zf-C2H2_9 PF16293.5 AIO00262.1 - 0.023 14.5 11.4 13 5.7 0.2 4.6 4 0 0 4 4 4 0 C2H2 type zinc-finger (1 copy) Zf_RING PF16744.5 AIO00262.1 - 0.03 14.4 7.3 1 9.5 0.0 4.0 4 0 0 4 4 3 0 KIAA1045 RING finger zinc_ribbon_5 PF13719.6 AIO00262.1 - 0.12 12.2 5.8 38 4.2 0.0 4.4 4 0 0 4 4 4 0 zinc-ribbon domain IBR PF01485.21 AIO00262.1 - 0.14 12.4 8.6 12 6.2 0.1 3.9 4 0 0 4 4 3 0 IBR domain, a half RING-finger domain zf-tcix PF14952.6 AIO00262.1 - 0.15 11.7 0.0 0.15 11.7 0.0 2.4 3 0 0 3 3 2 0 Putative treble-clef, zinc-finger, Zn-binding zf-H2C2_2 PF13465.6 AIO00262.1 - 0.17 12.4 0.2 0.17 12.4 0.2 7.0 7 1 0 7 7 6 0 Zinc-finger double domain zf-C2H2_3rep PF18868.1 AIO00262.1 - 0.23 12.1 19.7 5 7.8 4.2 5.9 3 1 5 8 8 8 0 Zinc finger C2H2-type, 3 repeats zf_UBZ PF18439.1 AIO00262.1 - 0.41 10.3 20.4 1.3 8.6 2.0 6.1 5 1 1 6 6 6 0 Ubiquitin-Binding Zinc Finger zf-C2H2_2 PF12756.7 AIO00262.1 - 0.42 11.0 24.6 0.75 10.2 0.5 6.5 5 2 2 7 7 7 0 C2H2 type zinc-finger (2 copies) OrfB_Zn_ribbon PF07282.11 AIO00262.1 - 0.5 10.3 2.3 7.8 6.5 0.1 3.3 3 0 0 3 3 3 0 Putative transposase DNA-binding domain GAGA PF09237.11 AIO00262.1 - 1.2 9.0 3.8 13 5.7 0.0 3.5 4 0 0 4 4 3 0 GAGA factor zf-TFIIB PF13453.6 AIO00262.1 - 1.3 8.4 11.3 1.5 8.2 0.3 3.9 4 0 0 4 4 3 0 Transcription factor zinc-finger Zn_ribbon_SprT PF17283.2 AIO00262.1 - 1.4 8.9 5.1 18 5.4 0.1 3.7 3 0 0 3 3 3 0 SprT-like zinc ribbon domain zinc_ribbon_9 PF14369.6 AIO00262.1 - 1.6 9.0 17.7 2.7 8.3 0.2 5.6 5 1 0 5 5 5 0 zinc-ribbon zf-C2HC_2 PF13913.6 AIO00262.1 - 2.9 7.9 19.8 0.081 12.9 1.1 5.2 5 0 0 5 5 5 0 zinc-finger of a C2HC-type Evr1_Alr PF04777.13 AIO00262.1 - 3 8.4 10.0 9 6.8 0.1 4.4 3 1 1 4 4 3 0 Erv1 / Alr family zf-C2H2_6 PF13912.6 AIO00262.1 - 3.4 7.8 16.1 7.6 6.7 0.3 5.1 5 1 0 5 5 4 0 C2H2-type zinc finger CpXC PF14353.6 AIO00262.1 - 4.4 7.4 10.9 4.9 7.2 0.0 4.7 4 1 1 5 5 5 0 CpXC protein Rad50_zn_hook PF04423.14 AIO00262.1 - 6.3 6.7 10.7 38 4.2 0.5 4.3 4 0 0 4 4 4 0 Rad50 zinc hook motif Peptidase_C54 PF03416.19 AIO00263.1 - 2.9e-45 154.8 0.1 6.2e-45 153.7 0.1 1.5 1 1 0 1 1 1 1 Peptidase family C54 COP23 PF14218.6 AIO00263.1 - 0.0061 16.3 0.1 0.013 15.2 0.1 1.5 1 0 0 1 1 1 1 Circadian oscillating protein COP23 Peptidase_C78 PF07910.13 AIO00263.1 - 0.044 13.3 0.0 0.089 12.3 0.0 1.4 1 0 0 1 1 1 0 Peptidase family C78 LIM PF00412.22 AIO00264.1 - 3.8e-05 23.8 12.4 0.00011 22.4 9.7 2.5 2 1 0 2 2 2 1 LIM domain NCD3G PF07562.14 AIO00264.1 - 0.064 13.2 4.9 4.7 7.3 0.1 2.4 2 0 0 2 2 2 0 Nine Cysteines Domain of family 3 GPCR zf-PARP PF00645.18 AIO00264.1 - 0.26 12.2 3.2 6.9 7.6 2.1 2.4 2 0 0 2 2 2 0 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region Hpt PF01627.23 AIO00265.1 - 0.071 13.4 0.1 0.19 12.0 0.1 1.7 1 0 0 1 1 1 0 Hpt domain Sad1_UNC PF07738.13 AIO00268.1 - 5e-18 65.4 0.0 8.4e-18 64.7 0.0 1.3 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal Spc7 PF08317.11 AIO00268.1 - 0.046 12.6 3.0 0.067 12.1 3.0 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein CEP63 PF17045.5 AIO00268.1 - 0.062 13.2 2.2 0.091 12.7 2.2 1.1 1 0 0 1 1 1 0 Centrosomal protein of 63 kDa ATG16 PF08614.11 AIO00268.1 - 0.11 12.7 3.0 0.18 12.0 3.0 1.2 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) Occludin_ELL PF07303.13 AIO00268.1 - 1.1 10.1 4.2 3.9 8.3 0.5 2.0 1 1 1 2 2 2 0 Occludin homology domain DUF1043 PF06295.12 AIO00268.1 - 3.8 7.5 5.3 6.4 6.8 5.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) FAM104 PF15434.6 AIO00269.1 - 0.033 14.7 2.8 0.038 14.6 0.1 2.0 1 1 1 2 2 2 0 Family 104 Ku PF02735.16 AIO00270.1 - 1.2e-27 96.9 0.0 1.9e-27 96.3 0.0 1.3 1 0 0 1 1 1 1 Ku70/Ku80 beta-barrel domain Ku_PK_bind PF08785.11 AIO00270.1 - 3.4e-20 72.4 0.1 1.4e-19 70.4 0.0 2.0 2 0 0 2 2 2 1 Ku C terminal domain like Ku_N PF03731.15 AIO00270.1 - 4.5e-08 33.1 0.0 1e-07 31.9 0.0 1.5 1 1 0 1 1 1 1 Ku70/Ku80 N-terminal alpha/beta domain Ku_C PF03730.14 AIO00270.1 - 0.0017 19.0 0.1 0.0039 17.8 0.1 1.5 1 0 0 1 1 1 1 Ku70/Ku80 C-terminal arm VWA PF00092.28 AIO00270.1 - 0.011 16.0 0.0 0.027 14.7 0.0 1.6 1 0 0 1 1 1 0 von Willebrand factor type A domain VWA_2 PF13519.6 AIO00270.1 - 0.045 14.4 0.2 1.1 9.9 0.1 3.1 2 1 0 2 2 2 0 von Willebrand factor type A domain Kinesin PF00225.23 AIO00271.1 - 9e-91 304.2 1.3 1.3e-90 303.7 1.3 1.2 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 AIO00271.1 - 5e-27 94.7 0.6 1.6e-26 93.0 0.3 2.0 2 0 0 2 2 2 1 Microtubule binding TSC22 PF01166.18 AIO00271.1 - 0.00046 20.4 0.2 0.0019 18.5 0.2 2.0 1 0 0 1 1 1 1 TSC-22/dip/bun family YabA PF06156.13 AIO00271.1 - 0.0061 17.2 0.3 0.0061 17.2 0.3 2.7 2 1 1 3 3 3 1 Initiation control protein YabA AAA_16 PF13191.6 AIO00271.1 - 0.0075 16.7 1.4 0.022 15.1 0.0 2.4 2 1 0 2 2 2 1 AAA ATPase domain NRBF2 PF08961.10 AIO00271.1 - 0.012 15.3 1.6 0.029 14.0 1.6 1.6 1 0 0 1 1 1 0 Nuclear receptor-binding factor 2, autophagy regulator bZIP_1 PF00170.21 AIO00271.1 - 0.012 15.7 0.1 0.012 15.7 0.1 2.4 2 0 0 2 2 2 0 bZIP transcription factor PIF1 PF05970.14 AIO00271.1 - 0.015 14.5 0.2 0.03 13.5 0.2 1.5 1 0 0 1 1 1 0 PIF1-like helicase AAA_22 PF13401.6 AIO00271.1 - 0.034 14.4 0.5 0.23 11.7 0.2 2.5 2 1 0 2 2 2 0 AAA domain EMP70 PF02990.16 AIO00272.1 - 1.8e-151 505.3 9.4 2.5e-151 504.9 9.4 1.2 1 0 0 1 1 1 1 Endomembrane protein 70 Pkinase PF00069.25 AIO00273.1 - 9.5e-60 202.2 0.0 2.5e-59 200.8 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 AIO00273.1 - 2.3e-26 92.6 0.0 3.2e-26 92.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 AIO00273.1 - 4.3e-05 23.0 0.0 0.00013 21.4 0.0 1.6 2 0 0 2 2 2 1 Kinase-like DUF3455 PF11937.8 AIO00273.1 - 0.098 13.0 0.0 0.15 12.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3455) Seadorna_VP7 PF07387.11 AIO00273.1 - 0.19 10.7 0.0 0.33 10.0 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 PP2C PF00481.21 AIO00274.1 - 4.5e-49 167.4 0.1 6.3e-49 166.9 0.1 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.12 AIO00274.1 - 0.0011 18.9 0.0 0.0056 16.6 0.0 2.0 1 1 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) GPS PF01825.21 AIO00275.1 - 0.15 12.6 3.0 3.9 8.1 0.0 2.4 2 0 0 2 2 2 0 GPCR proteolysis site, GPS, motif SHQ1 PF04925.15 AIO00275.1 - 0.17 11.5 0.0 0.29 10.7 0.0 1.3 1 0 0 1 1 1 0 SHQ1 protein Hydrolase_4 PF12146.8 AIO00276.1 - 1.2e-12 47.7 0.0 8.6e-09 35.0 0.0 2.2 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 AIO00276.1 - 8.5e-09 35.4 0.2 1.9e-05 24.4 0.2 2.2 1 1 1 2 2 2 2 alpha/beta hydrolase fold Peptidase_S15 PF02129.18 AIO00276.1 - 1.7e-07 31.1 0.0 9.4e-07 28.7 0.0 1.9 1 1 1 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) Peptidase_S9 PF00326.21 AIO00276.1 - 5e-05 22.9 0.1 0.00076 19.0 0.1 2.1 1 1 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_6 PF12697.7 AIO00276.1 - 0.001 19.7 0.0 0.0015 19.2 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family AXE1 PF05448.12 AIO00276.1 - 0.012 14.3 0.0 2.4 6.8 0.0 2.4 1 1 1 2 2 2 0 Acetyl xylan esterase (AXE1) FSH1 PF03959.13 AIO00276.1 - 0.03 14.0 0.0 0.061 13.0 0.0 1.5 1 1 0 1 1 1 0 Serine hydrolase (FSH1) PhoPQ_related PF10142.9 AIO00276.1 - 0.031 13.0 0.0 0.036 12.7 0.0 1.1 1 0 0 1 1 1 0 PhoPQ-activated pathogenicity-related protein Esterase PF00756.20 AIO00276.1 - 0.041 13.5 0.0 0.06 13.0 0.0 1.2 1 0 0 1 1 1 0 Putative esterase PAP2 PF01569.21 AIO00277.1 - 8.7e-21 74.1 2.5 1.3e-20 73.5 2.5 1.3 1 0 0 1 1 1 1 PAP2 superfamily TM2 PF05154.16 AIO00277.1 - 0.16 12.3 3.4 0.35 11.2 3.4 1.6 1 0 0 1 1 1 0 TM2 domain DUF4149 PF13664.6 AIO00277.1 - 1.3 9.4 6.3 2.4 8.6 0.1 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF4149) WD40 PF00400.32 AIO00278.1 - 1.3e-28 98.6 14.5 4.7e-09 36.7 0.5 7.3 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 AIO00278.1 - 1.1e-14 54.5 0.5 0.00016 21.9 0.0 5.4 1 1 4 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 AIO00278.1 - 0.0011 18.0 0.0 0.052 12.5 0.0 2.5 1 1 1 2 2 2 2 WD40 region of Ge1, enhancer of mRNA-decapping protein DAGK_cat PF00781.24 AIO00279.1 - 3.5e-13 49.3 0.0 5.4e-13 48.7 0.0 1.3 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain Evr1_Alr PF04777.13 AIO00280.1 - 1.2e-15 57.8 0.4 2.8e-15 56.6 0.2 1.8 1 1 0 1 1 1 1 Erv1 / Alr family Thioredoxin PF00085.20 AIO00280.1 - 6e-08 32.6 0.0 1.3e-07 31.5 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin OST3_OST6 PF04756.13 AIO00280.1 - 0.014 14.8 0.0 0.13 11.6 0.0 2.3 3 0 0 3 3 3 0 OST3 / OST6 family, transporter family DUF3693 PF12472.8 AIO00280.1 - 0.05 13.3 0.3 0.19 11.4 0.2 2.1 2 0 0 2 2 2 0 Phage related protein RRF PF01765.19 AIO00281.1 - 1.5e-14 54.3 3.0 3e-14 53.3 0.7 1.9 1 1 1 2 2 2 1 Ribosome recycling factor IF4E PF01652.18 AIO00282.1 - 1.8e-27 96.1 0.0 2.4e-27 95.7 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E PAM2 PF07145.15 AIO00282.1 - 0.66 9.8 2.5 0.74 9.6 0.1 2.2 2 0 0 2 2 2 0 Ataxin-2 C-terminal region tRNA-synt_2 PF00152.20 AIO00283.1 - 1.9e-74 250.6 0.1 2.9e-74 250.0 0.1 1.3 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 AIO00283.1 - 1.4e-08 34.6 0.4 2.4e-08 33.8 0.4 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 AIO00283.1 - 0.00028 20.4 0.4 0.92 8.9 0.1 2.6 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) Bystin PF05291.11 AIO00285.1 - 7.1e-110 366.9 1.2 9.8e-110 366.4 1.2 1.1 1 0 0 1 1 1 1 Bystin DUF3299 PF11736.8 AIO00285.1 - 0.0021 18.0 0.1 0.013 15.5 0.1 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF3299) GPHR_N PF12537.8 AIO00286.1 - 3.7 7.7 4.5 25 5.0 0.6 2.8 2 0 0 2 2 2 0 The Golgi pH Regulator (GPHR) Family N-terminal LRR_4 PF12799.7 AIO00288.1 - 4.8e-07 30.0 1.5 0.0014 19.0 0.0 3.2 3 0 0 3 3 3 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 AIO00288.1 - 0.001 18.8 1.9 0.0034 17.1 0.4 2.4 2 1 0 2 2 2 1 Leucine rich repeat LRR_9 PF14580.6 AIO00288.1 - 0.015 14.8 0.0 0.027 14.0 0.0 1.3 1 0 0 1 1 1 0 Leucine-rich repeat NatB_MDM20 PF09797.9 AIO00289.1 - 1.3e-24 86.9 0.0 8.5e-24 84.2 0.0 2.0 2 0 0 2 2 2 1 N-acetyltransferase B complex (NatB) non catalytic subunit TPR_16 PF13432.6 AIO00289.1 - 0.2 12.4 2.6 1.5 9.5 0.3 3.4 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.6 AIO00289.1 - 4.3 8.4 19.1 0.31 12.0 0.3 6.3 7 1 1 8 8 8 0 Tetratricopeptide repeat Alg14 PF08660.11 AIO00290.1 - 5.3e-54 182.8 0.0 7.4e-54 182.3 0.0 1.2 1 0 0 1 1 1 1 Oligosaccharide biosynthesis protein Alg14 like Glyco_tran_28_C PF04101.16 AIO00290.1 - 1.7e-18 67.2 0.0 3.9e-18 66.0 0.0 1.6 1 1 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain RRM_1 PF00076.22 AIO00291.1 - 2.1e-16 59.5 0.0 3.1e-16 58.9 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) LMBR1 PF04791.16 AIO00292.1 - 1.2e-53 182.8 22.2 1.7e-53 182.3 22.2 1.1 1 0 0 1 1 1 1 LMBR1-like membrane protein DUF3037 PF11236.8 AIO00293.1 - 0.41 11.1 4.8 5.1 7.5 0.1 3.1 1 1 2 3 3 3 0 Protein of unknown function (DUF3037) DUF4407 PF14362.6 AIO00293.1 - 7.9 5.7 17.1 0.43 9.9 7.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) PSP PF04046.16 AIO00294.1 - 1.2e-18 66.6 3.0 2.7e-18 65.5 3.0 1.6 1 0 0 1 1 1 1 PSP DUF382 PF04037.13 AIO00294.1 - 1.2e-11 44.8 0.0 1.2e-11 44.8 0.0 2.5 2 1 0 2 2 2 1 Domain of unknown function (DUF382) LUC7 PF03194.15 AIO00294.1 - 0.2 11.3 6.8 0.26 10.9 6.8 1.2 1 0 0 1 1 1 0 LUC7 N_terminus Rtf2 PF04641.12 AIO00294.1 - 7.9 5.7 8.6 15 4.8 0.0 2.2 2 0 0 2 2 2 0 Rtf2 RING-finger AMP-binding PF00501.28 AIO00295.1 - 8.5e-25 87.2 0.0 2.2e-11 43.0 0.0 2.1 2 0 0 2 2 2 2 AMP-binding enzyme BBS2_C PF14782.6 AIO00296.1 - 1.3e-131 439.3 0.0 1.7e-131 438.9 0.0 1.1 1 0 0 1 1 1 1 Ciliary BBSome complex subunit 2, C-terminal BBS2_Mid PF14783.6 AIO00296.1 - 9.5e-23 80.3 0.0 7.7e-22 77.4 0.0 2.5 2 1 0 2 2 2 1 Ciliary BBSome complex subunit 2, middle region FG-GAP PF01839.23 AIO00296.1 - 0.00027 21.0 1.6 0.00047 20.2 0.7 1.9 2 0 0 2 2 2 1 FG-GAP repeat VCBS PF13517.6 AIO00296.1 - 0.0032 18.0 0.1 0.0078 16.8 0.1 1.7 1 0 0 1 1 1 1 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella APG6_N PF17675.1 AIO00296.1 - 0.04 14.4 0.2 0.04 14.4 0.2 2.0 2 0 0 2 2 2 0 Apg6 coiled-coil region FlgN PF05130.12 AIO00296.1 - 1.3 9.5 9.2 0.094 13.2 0.6 2.7 2 1 1 3 3 3 0 FlgN protein Pkinase PF00069.25 AIO00297.1 - 2.2e-64 217.4 0.0 2.8e-64 217.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 AIO00297.1 - 1.5e-40 139.1 0.0 2.1e-40 138.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 AIO00297.1 - 0.00036 19.9 0.0 0.00068 19.0 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 AIO00297.1 - 0.013 14.2 0.0 0.033 13.0 0.0 1.6 1 0 0 1 1 1 0 Fungal protein kinase Cyt-b5 PF00173.28 AIO00298.1 - 5e-26 90.6 0.0 3.1e-16 59.3 0.0 2.9 3 0 0 3 3 3 2 Cytochrome b5-like Heme/Steroid binding domain NAD_binding_1 PF00175.21 AIO00298.1 - 2.5e-10 40.9 0.0 7.8e-10 39.4 0.0 1.9 1 1 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.12 AIO00298.1 - 0.0033 17.6 0.0 0.013 15.7 0.0 1.9 2 0 0 2 2 2 1 Ferric reductase NAD binding domain FAD_binding_6 PF00970.24 AIO00298.1 - 0.045 14.1 0.0 0.1 13.0 0.0 1.6 1 0 0 1 1 1 0 Oxidoreductase FAD-binding domain RRS1 PF04939.12 AIO00299.1 - 5.5e-42 143.4 4.5 5.5e-42 143.4 4.5 1.6 2 0 0 2 2 2 1 Ribosome biogenesis regulatory protein (RRS1) tRNA-synt_His PF13393.6 AIO00300.1 - 1.7e-37 129.4 0.0 2.4e-37 128.9 0.0 1.2 1 0 0 1 1 1 1 Histidyl-tRNA synthetase HGTP_anticodon PF03129.20 AIO00300.1 - 4.5e-07 29.9 0.3 1.1e-06 28.7 0.1 1.7 2 0 0 2 2 2 1 Anticodon binding domain tRNA-synt_2b PF00587.25 AIO00300.1 - 4.5e-05 23.5 0.0 5.3e-05 23.3 0.0 1.4 1 1 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) DUF4473 PF14747.6 AIO00300.1 - 0.059 13.9 0.0 0.14 12.7 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4473) CedA PF10729.9 AIO00302.1 - 0.092 12.6 0.1 0.3 10.9 0.0 1.9 2 0 0 2 2 2 0 Cell division activator CedA DUF1965 PF09248.10 AIO00302.1 - 0.11 12.3 0.1 0.32 10.8 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1965) PDZ_2 PF13180.6 AIO00303.1 - 1.8e-10 41.0 0.0 1.1e-09 38.5 0.0 2.2 2 0 0 2 2 2 1 PDZ domain PDZ_6 PF17820.1 AIO00303.1 - 3e-07 30.2 0.0 7.6e-07 28.9 0.0 1.7 1 0 0 1 1 1 1 PDZ domain PI-PLC-X PF00388.19 AIO00303.1 - 1.4e-06 28.0 0.0 2.6e-06 27.1 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PDZ PF00595.24 AIO00303.1 - 4.1e-05 23.8 0.0 9.2e-05 22.7 0.0 1.5 1 0 0 1 1 1 1 PDZ domain PI-PLC-Y PF00387.19 AIO00303.1 - 0.051 13.9 0.0 0.12 12.7 0.0 1.6 1 0 0 1 1 1 0 Phosphatidylinositol-specific phospholipase C, Y domain EF-hand_like PF09279.11 AIO00303.1 - 0.057 13.9 0.1 0.13 12.8 0.1 1.5 1 0 0 1 1 1 0 Phosphoinositide-specific phospholipase C, efhand-like Ribosomal_S30 PF04758.14 AIO00304.1 - 2.1e-25 88.6 8.7 2.5e-25 88.5 8.7 1.0 1 0 0 1 1 1 1 Ribosomal protein S30 Ribosomal_S30 PF04758.14 AIO00305.1 - 1.3e-25 89.3 9.1 1.5e-25 89.1 9.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S30 Ribosomal_S30 PF04758.14 AIO00306.1 - 2.1e-25 88.6 8.7 2.5e-25 88.5 8.7 1.0 1 0 0 1 1 1 1 Ribosomal protein S30 CS PF04969.16 AIO00307.1 - 1.7e-14 54.6 0.0 2.8e-14 53.9 0.0 1.3 1 0 0 1 1 1 1 CS domain TPR_2 PF07719.17 AIO00309.1 - 5.8e-25 85.4 17.9 0.00087 19.2 0.4 9.1 9 0 0 9 9 9 6 Tetratricopeptide repeat TPR_1 PF00515.28 AIO00309.1 - 3.8e-22 77.1 17.2 3.4e-05 23.5 0.4 7.8 8 0 0 8 8 8 6 Tetratricopeptide repeat TPR_8 PF13181.6 AIO00309.1 - 2.1e-18 64.9 10.6 0.0001 22.2 0.1 6.9 8 0 0 8 8 6 5 Tetratricopeptide repeat TPR_12 PF13424.6 AIO00309.1 - 2.1e-16 59.9 10.5 7.6e-08 32.5 0.1 6.4 4 2 2 6 6 6 4 Tetratricopeptide repeat TPR_19 PF14559.6 AIO00309.1 - 1.2e-14 54.6 2.6 0.00073 20.0 0.1 6.4 5 2 1 6 6 6 2 Tetratricopeptide repeat TPR_16 PF13432.6 AIO00309.1 - 3.5e-13 50.0 4.0 0.0025 18.4 0.0 5.7 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_7 PF13176.6 AIO00309.1 - 5.1e-13 48.1 9.2 0.00088 19.1 0.2 7.2 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_14 PF13428.6 AIO00309.1 - 1.3e-10 41.2 6.0 2.3 9.3 0.0 8.7 8 2 1 9 9 9 2 Tetratricopeptide repeat ANAPC3 PF12895.7 AIO00309.1 - 5.3e-10 39.4 23.2 2.7e-05 24.3 0.1 4.5 5 1 1 6 6 4 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.6 AIO00309.1 - 2.3e-07 30.7 7.3 0.11 12.9 0.0 6.9 7 1 0 7 7 6 1 Tetratricopeptide repeat TPR_6 PF13174.6 AIO00309.1 - 4.7e-07 30.0 10.6 0.0011 19.4 0.8 6.1 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_11 PF13414.6 AIO00309.1 - 1.3e-06 28.0 11.0 0.0091 15.7 0.3 5.4 4 2 2 6 6 6 2 TPR repeat TPR_15 PF13429.6 AIO00309.1 - 2.2e-05 23.8 0.3 0.37 10.0 0.0 4.0 2 2 3 5 5 5 2 Tetratricopeptide repeat TPR_9 PF13371.6 AIO00309.1 - 0.00014 22.0 1.3 0.037 14.2 0.0 4.1 4 0 0 4 4 4 1 Tetratricopeptide repeat SNAP PF14938.6 AIO00309.1 - 0.014 14.9 6.8 0.037 13.4 3.0 2.9 2 1 0 2 2 2 0 Soluble NSF attachment protein, SNAP Sel1 PF08238.12 AIO00309.1 - 0.019 15.7 6.0 23 5.8 0.1 4.8 4 0 0 4 4 4 0 Sel1 repeat Alkyl_sulf_dimr PF14863.6 AIO00309.1 - 0.039 14.4 0.0 19 5.7 0.0 3.4 2 1 1 3 3 3 0 Alkyl sulfatase dimerisation TPR_10 PF13374.6 AIO00309.1 - 0.065 13.1 9.4 2.9 7.9 0.4 5.6 7 0 0 7 7 7 0 Tetratricopeptide repeat NARP1 PF12569.8 AIO00309.1 - 0.089 11.7 0.1 0.29 10.0 0.0 1.8 2 0 0 2 2 2 0 NMDA receptor-regulated protein 1 DUF3856 PF12968.7 AIO00309.1 - 0.19 11.8 2.6 0.65 10.1 0.2 2.8 3 0 0 3 3 3 0 Domain of Unknown Function (DUF3856) BTAD PF03704.17 AIO00309.1 - 0.21 12.0 9.8 3 8.3 0.1 4.5 4 2 0 5 5 5 0 Bacterial transcriptional activator domain Fis1_TPR_C PF14853.6 AIO00309.1 - 0.3 11.2 14.5 7.2 6.8 0.1 5.2 5 0 0 5 5 5 0 Fis1 C-terminal tetratricopeptide repeat GrpE PF01025.19 AIO00311.1 - 2.5e-41 141.1 3.3 3e-41 140.8 3.3 1.1 1 0 0 1 1 1 1 GrpE Bcr-Abl_Oligo PF09036.10 AIO00311.1 - 0.14 12.2 0.1 0.28 11.2 0.1 1.5 1 0 0 1 1 1 0 Bcr-Abl oncoprotein oligomerisation domain GrpE PF01025.19 AIO00312.1 - 1.2e-37 129.1 2.8 1.6e-37 128.8 2.8 1.1 1 0 0 1 1 1 1 GrpE Spore_III_AB PF09548.10 AIO00312.1 - 0.027 14.6 0.2 0.043 13.9 0.2 1.2 1 0 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) WXG100 PF06013.12 AIO00312.1 - 0.037 14.3 2.3 0.053 13.8 2.3 1.2 1 0 0 1 1 1 0 Proteins of 100 residues with WXG Herpes_US9 PF06072.11 AIO00312.1 - 0.098 12.5 0.0 0.23 11.3 0.0 1.6 1 0 0 1 1 1 0 Alphaherpesvirus tegument protein US9 YabA PF06156.13 AIO00312.1 - 0.24 12.1 4.4 0.59 10.8 2.7 2.1 1 1 1 2 2 2 0 Initiation control protein YabA DJ-1_PfpI PF01965.24 AIO00315.1 - 4.4e-30 104.6 0.1 5.4e-30 104.4 0.1 1.1 1 0 0 1 1 1 1 DJ-1/PfpI family ThiJ_like PF17124.5 AIO00315.1 - 0.064 12.9 0.0 0.094 12.4 0.0 1.3 1 0 0 1 1 1 0 ThiJ/PfpI family-like Arm PF00514.23 AIO00316.1 - 1.7e-19 69.2 19.6 0.16 12.1 0.0 12.1 12 0 0 12 12 12 5 Armadillo/beta-catenin-like repeat Atx10homo_assoc PF09759.9 AIO00316.1 - 7.5e-18 64.4 13.3 0.0054 16.7 0.0 8.7 3 3 5 9 9 9 6 Spinocerebellar ataxia type 10 protein domain HEAT_2 PF13646.6 AIO00316.1 - 5.2e-07 30.0 6.7 0.018 15.4 0.5 5.6 4 1 1 5 5 5 2 HEAT repeats HEAT_EZ PF13513.6 AIO00316.1 - 9.3e-05 22.8 13.5 0.17 12.4 0.5 6.5 6 2 1 7 7 7 2 HEAT-like repeat DOG1 PF14144.6 AIO00316.1 - 0.052 13.8 7.4 2.2 8.5 0.0 4.8 4 1 0 4 4 4 0 Seed dormancy control FliG_N PF14842.6 AIO00316.1 - 0.072 13.6 2.1 4.1 8.0 0.1 3.8 4 0 0 4 4 4 0 FliG N-terminal domain DUF3349 PF11829.8 AIO00316.1 - 0.19 12.5 2.7 38 5.1 0.0 4.5 5 0 0 5 5 5 0 Protein of unknown function (DUF3349) UME PF08064.13 AIO00316.1 - 0.57 10.1 6.3 1.4 8.8 0.1 4.3 4 1 0 4 4 4 0 UME (NUC010) domain RIIa PF02197.17 AIO00317.1 - 0.049 13.3 0.1 0.14 11.9 0.0 1.8 2 0 0 2 2 2 0 Regulatory subunit of type II PKA R-subunit Pkinase PF00069.25 AIO00320.1 - 2e-70 237.2 0.1 5.8e-70 235.7 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 AIO00320.1 - 1.5e-31 109.6 0.0 2.6e-31 108.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase PH PF00169.29 AIO00320.1 - 8.7e-06 26.2 0.1 2.5e-05 24.7 0.1 1.8 1 0 0 1 1 1 1 PH domain Kinase-like PF14531.6 AIO00320.1 - 0.00035 20.0 0.0 0.00088 18.7 0.0 1.7 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.14 AIO00320.1 - 0.02 14.3 0.0 0.044 13.1 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 AIO00320.1 - 0.043 13.7 0.0 0.081 12.8 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family GH97_C PF14509.6 AIO00320.1 - 0.051 13.8 0.0 0.49 10.7 0.0 2.4 2 0 0 2 2 2 0 Glycosyl-hydrolase 97 C-terminal, oligomerisation FAM220 PF15487.6 AIO00320.1 - 1.3 8.6 3.9 2.1 7.9 3.9 1.2 1 0 0 1 1 1 0 FAM220 family Methyltransf_PK PF05891.12 AIO00321.1 - 2.3e-66 223.5 0.0 2.8e-66 223.2 0.0 1.0 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase Methyltransf_25 PF13649.6 AIO00321.1 - 3.6e-12 46.8 0.0 6e-12 46.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 AIO00321.1 - 7.8e-12 45.7 0.0 1.2e-11 45.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 AIO00321.1 - 8.2e-07 29.0 0.0 1.3e-06 28.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 AIO00321.1 - 4.4e-06 27.3 0.0 7.8e-06 26.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 AIO00321.1 - 4.5e-06 26.5 0.0 1.8e-05 24.6 0.0 1.8 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_2 PF00891.18 AIO00321.1 - 4.1e-05 23.0 0.0 5.8e-05 22.5 0.0 1.3 1 1 0 1 1 1 1 O-methyltransferase domain MTS PF05175.14 AIO00321.1 - 7.8e-05 22.3 0.0 0.00013 21.5 0.0 1.3 1 1 0 1 1 1 1 Methyltransferase small domain Bin3 PF06859.12 AIO00321.1 - 0.16 12.6 0.0 0.3 11.8 0.0 1.4 1 0 0 1 1 1 0 Bicoid-interacting protein 3 (Bin3) Phage_GPL PF05926.11 AIO00322.1 - 0.77 9.8 5.9 0.57 10.2 0.5 2.8 2 0 0 2 2 2 0 Phage head completion protein (GPL) DUF4407 PF14362.6 AIO00322.1 - 6.6 6.0 10.5 1.3 8.3 1.6 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Prefoldin_2 PF01920.20 AIO00323.1 - 6.6e-07 29.2 1.9 6.6e-07 29.2 1.9 1.7 1 1 0 1 1 1 1 Prefoldin subunit UPF0242 PF06785.11 AIO00323.1 - 0.075 13.1 3.4 0.096 12.8 3.4 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DUF722 PF05263.11 AIO00323.1 - 0.1 12.8 1.1 0.24 11.6 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF722) CENP-K PF11802.8 AIO00323.1 - 1.1 8.8 7.9 0.23 11.0 0.5 2.0 2 0 0 2 2 2 0 Centromere-associated protein K MMR_HSR1 PF01926.23 AIO00324.1 - 5.6e-07 29.6 0.0 0.00016 21.7 0.0 3.4 2 1 0 2 2 2 1 50S ribosome-binding GTPase ATP_bind_1 PF03029.17 AIO00324.1 - 9.8e-06 25.5 0.0 0.00056 19.8 0.0 2.9 3 0 0 3 3 3 1 Conserved hypothetical ATP binding protein Dynamin_N PF00350.23 AIO00324.1 - 4.6e-05 23.6 0.0 0.0012 18.9 0.0 2.4 2 1 0 2 2 2 1 Dynamin family GTP_EFTU PF00009.27 AIO00324.1 - 0.0002 21.0 0.0 0.00042 19.9 0.0 1.5 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.18 AIO00324.1 - 0.00044 19.8 0.1 0.28 10.7 0.0 2.7 2 0 0 2 2 2 2 Ferrous iron transport protein B RsgA_GTPase PF03193.16 AIO00324.1 - 0.01 15.8 0.0 0.32 10.9 0.0 3.0 2 1 0 2 2 2 0 RsgA GTPase Amastin PF07344.11 AIO00325.1 - 3.3e-44 150.4 9.6 4e-44 150.2 9.6 1.1 1 0 0 1 1 1 1 Amastin surface glycoprotein Amastin PF07344.11 AIO00326.1 - 5.5e-39 133.5 4.5 6.6e-39 133.2 4.5 1.1 1 0 0 1 1 1 1 Amastin surface glycoprotein zf-LITAF-like PF10601.9 AIO00326.1 - 0.59 10.4 3.3 19 5.6 0.0 3.2 2 1 2 4 4 4 0 LITAF-like zinc ribbon domain PfkB PF00294.24 AIO00327.1 - 5.3e-55 186.9 0.3 6.5e-55 186.6 0.3 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase DAGK_cat PF00781.24 AIO00327.1 - 0.027 14.1 0.0 0.066 12.8 0.0 1.6 1 0 0 1 1 1 0 Diacylglycerol kinase catalytic domain ThiG PF05690.14 AIO00327.1 - 0.049 12.9 0.0 0.27 10.5 0.0 1.9 2 0 0 2 2 2 0 Thiazole biosynthesis protein ThiG HECT PF00632.25 AIO00329.1 - 3.6e-76 256.6 0.0 5.1e-76 256.1 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) DUF2164 PF09932.9 AIO00330.1 - 0.034 14.2 0.0 0.1 12.7 0.0 1.8 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2164) DUF4139 PF13598.6 AIO00331.1 - 4.4e-45 153.9 0.0 6.8e-45 153.3 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4139) DUF4140 PF13600.6 AIO00331.1 - 5.1e-05 23.6 3.7 0.0022 18.4 0.7 2.6 2 0 0 2 2 2 2 N-terminal domain of unknown function (DUF4140) ADIP PF11559.8 AIO00331.1 - 0.26 11.4 0.9 14 5.8 0.1 2.2 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding SlyX PF04102.12 AIO00331.1 - 0.81 10.3 2.5 9.1 7.0 0.3 2.5 2 0 0 2 2 2 0 SlyX GCP_C_terminal PF04130.13 AIO00332.1 - 3.1e-22 79.5 0.3 7.5e-22 78.2 0.3 1.6 1 1 0 1 1 1 1 Gamma tubulin complex component C-terminal GCP_N_terminal PF17681.1 AIO00332.1 - 9.8e-05 22.1 0.0 0.00085 19.0 0.0 2.1 1 1 0 1 1 1 1 Gamma tubulin complex component N-terminal RWP-RK PF02042.15 AIO00332.1 - 0.0093 15.9 0.0 0.032 14.2 0.0 1.9 1 0 0 1 1 1 1 RWP-RK domain CbiA PF01656.23 AIO00332.1 - 0.21 11.7 0.0 0.32 11.1 0.0 1.4 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain WD40 PF00400.32 AIO00333.1 - 3.7e-13 49.7 12.7 0.00037 21.2 0.7 5.7 5 0 0 5 5 5 4 WD domain, G-beta repeat CAF1C_H4-bd PF12265.8 AIO00333.1 - 2.1e-10 40.7 0.1 6.2e-10 39.2 0.0 1.8 2 0 0 2 2 2 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex ANAPC4_WD40 PF12894.7 AIO00333.1 - 9.9e-05 22.6 0.1 0.3 11.4 0.0 3.3 3 1 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain MAM33 PF02330.16 AIO00335.1 - 1.2e-30 107.0 1.3 8.8e-26 91.2 1.1 2.1 1 1 1 2 2 2 2 Mitochondrial glycoprotein ABM PF03992.16 AIO00335.1 - 0.014 15.5 0.1 0.2 11.8 0.0 2.4 2 0 0 2 2 2 0 Antibiotic biosynthesis monooxygenase APG5 PF04106.12 AIO00336.1 - 0.021 14.4 0.0 0.089 12.4 0.0 2.0 1 1 0 1 1 1 0 Autophagy protein Apg5 Pkinase PF00069.25 AIO00338.1 - 8e-37 127.0 0.0 6.9e-16 58.4 0.0 3.1 3 0 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.17 AIO00338.1 - 1e-22 80.7 0.0 1.1e-13 51.1 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 AIO00338.1 - 0.024 14.0 0.0 0.33 10.2 0.0 2.1 2 0 0 2 2 2 0 Kinase-like Med3 PF11593.8 AIO00338.1 - 0.062 12.5 2.3 6.3 5.9 0.0 2.3 2 0 0 2 2 2 0 Mediator complex subunit 3 fungal Ufd2P_core PF10408.9 AIO00339.1 - 9.8e-97 325.1 0.5 1.3e-96 324.7 0.5 1.1 1 0 0 1 1 1 1 Ubiquitin elongating factor core Thioredoxin PF00085.20 AIO00339.1 - 4.1e-22 78.1 0.0 8.8e-22 77.1 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 AIO00339.1 - 7.9e-07 29.5 1.3 3.7e-06 27.4 0.3 2.5 2 0 0 2 2 2 1 Thioredoxin-like domain OST3_OST6 PF04756.13 AIO00339.1 - 8.3e-07 28.6 0.0 1.4e-06 27.9 0.0 1.2 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin_8 PF13905.6 AIO00339.1 - 0.00025 21.3 0.1 0.062 13.6 0.1 2.7 1 1 1 2 2 2 1 Thioredoxin-like Thioredoxin_9 PF14595.6 AIO00339.1 - 0.00066 19.4 0.0 0.002 17.9 0.0 1.8 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_7 PF13899.6 AIO00339.1 - 0.0018 18.4 0.2 0.0067 16.6 0.1 2.1 2 0 0 2 2 2 1 Thioredoxin-like U-box PF04564.15 AIO00339.1 - 0.011 15.9 0.0 0.064 13.4 0.0 2.4 1 0 0 1 1 1 0 U-box domain AhpC-TSA PF00578.21 AIO00339.1 - 0.025 14.5 0.1 0.069 13.1 0.1 1.7 1 0 0 1 1 1 0 AhpC/TSA family Redoxin PF08534.10 AIO00339.1 - 0.13 12.0 0.2 1.6 8.4 0.1 2.2 1 1 1 2 2 2 0 Redoxin DnaJ PF00226.31 AIO00341.1 - 0.0066 16.5 0.0 0.016 15.3 0.0 1.7 1 0 0 1 1 1 1 DnaJ domain DUF4680 PF15730.5 AIO00341.1 - 2.5 8.5 12.5 0.49 10.7 6.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4680) Ribosomal_60s PF00428.19 AIO00341.1 - 5.9 7.5 0.0 5.9 7.5 0.0 3.1 3 1 0 3 3 3 0 60s Acidic ribosomal protein zf-CCHC_2 PF13696.6 AIO00342.1 - 2 8.3 4.2 1.4 8.8 1.4 2.2 2 0 0 2 2 2 0 Zinc knuckle Mito_carr PF00153.27 AIO00343.1 - 3.1e-46 155.2 2.2 5.5e-17 61.5 0.2 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein RF-1 PF00472.20 AIO00344.1 - 7.6e-15 54.9 0.0 1.1e-14 54.4 0.0 1.3 1 0 0 1 1 1 1 RF-1 domain MRP-S28 PF10213.9 AIO00344.1 - 0.0093 16.4 0.0 0.014 15.8 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal subunit protein TRF PF08558.10 AIO00344.1 - 0.16 11.5 0.0 0.22 11.1 0.0 1.1 1 0 0 1 1 1 0 Telomere repeat binding factor (TRF) Sdh5 PF03937.16 AIO00345.1 - 6.7e-19 67.6 0.9 1.3e-18 66.8 0.9 1.5 1 0 0 1 1 1 1 Flavinator of succinate dehydrogenase WW PF00397.26 AIO00346.1 - 1.2e-10 41.2 3.1 2.4e-10 40.3 3.1 1.5 1 0 0 1 1 1 1 WW domain ATG16 PF08614.11 AIO00346.1 - 0.009 16.3 0.8 0.009 16.3 0.8 3.3 3 0 0 3 3 3 1 Autophagy protein 16 (ATG16) DivIVA PF05103.13 AIO00346.1 - 0.12 12.5 5.3 4.4 7.4 0.0 2.5 2 0 0 2 2 2 0 DivIVA protein Nup54 PF13874.6 AIO00346.1 - 0.56 10.3 3.6 5.1 7.2 0.0 2.9 2 0 0 2 2 2 0 Nucleoporin complex subunit 54 Peptidase_M3_N PF08439.10 AIO00346.1 - 1.8 8.9 4.1 8.6 6.7 0.1 2.7 2 0 0 2 2 2 0 Oligopeptidase F DREV PF05219.12 AIO00347.1 - 7.4e-63 212.1 0.0 8.8e-63 211.9 0.0 1.0 1 0 0 1 1 1 1 DREV methyltransferase Methyltransf_12 PF08242.12 AIO00347.1 - 1.4e-12 48.2 0.0 2.4e-12 47.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 AIO00347.1 - 1.7e-11 44.6 0.0 3.2e-11 43.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 AIO00347.1 - 2.8e-11 43.5 0.0 3.9e-11 43.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 AIO00347.1 - 2.2e-08 34.7 0.0 4.8e-08 33.6 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 AIO00347.1 - 2e-05 24.4 0.0 0.00014 21.6 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain CheR PF01739.18 AIO00347.1 - 0.013 14.9 0.0 0.021 14.3 0.0 1.2 1 0 0 1 1 1 0 CheR methyltransferase, SAM binding domain RRM_1 PF00076.22 AIO00348.1 - 3.2e-21 74.9 0.0 2e-09 37.1 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RNA_bind PF08675.11 AIO00348.1 - 0.00093 19.2 0.0 0.11 12.5 0.0 2.9 3 0 0 3 3 3 1 RNA binding domain DUF4523 PF15023.6 AIO00348.1 - 0.0079 16.0 0.0 0.032 14.1 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF4523) Nup35_RRM_2 PF14605.6 AIO00348.1 - 0.0086 16.1 0.0 5.6 7.1 0.0 2.4 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif Arm PF00514.23 AIO00349.1 - 8.3e-69 225.7 20.1 4.2e-10 39.3 0.0 8.8 9 0 0 9 9 9 8 Armadillo/beta-catenin-like repeat Arm_3 PF16186.5 AIO00349.1 - 4.8e-15 54.9 0.0 1.6e-14 53.2 0.1 1.8 2 0 0 2 2 2 1 Atypical Arm repeat HEAT_2 PF13646.6 AIO00349.1 - 1.2e-13 51.3 3.3 0.0014 19.0 0.1 5.7 3 1 3 6 6 6 5 HEAT repeats HEAT_EZ PF13513.6 AIO00349.1 - 1.6e-12 47.6 12.1 0.00015 22.2 0.2 6.7 5 2 3 8 8 8 3 HEAT-like repeat HEAT PF02985.22 AIO00349.1 - 1.2e-10 40.7 10.6 0.084 13.2 0.0 8.1 9 0 0 9 9 9 4 HEAT repeat Arm_2 PF04826.13 AIO00349.1 - 0.0057 16.2 0.0 0.3 10.5 0.0 3.2 3 1 0 3 3 3 1 Armadillo-like DCB PF16213.5 AIO00349.1 - 0.028 14.1 0.0 0.06 13.0 0.0 1.5 1 0 0 1 1 1 0 Dimerisation and cyclophilin-binding domain of Mon2 Proteasom_PSMB PF10508.9 AIO00349.1 - 0.2 10.1 0.0 0.35 9.3 0.0 1.4 1 0 0 1 1 1 0 Proteasome non-ATPase 26S subunit Reticulon PF02453.17 AIO00351.1 - 1.7 8.6 12.2 19 5.2 12.1 2.5 1 1 0 1 1 1 0 Reticulon MA3 PF02847.17 AIO00352.1 - 1.1e-07 31.8 0.1 2.6e-07 30.6 0.1 1.6 1 0 0 1 1 1 1 MA3 domain DNA_pol3_gamma3 PF12169.8 AIO00352.1 - 0.25 11.3 4.1 1.1 9.2 0.0 3.6 4 0 0 4 4 4 0 DNA polymerase III subunits gamma and tau domain III DHHC PF01529.20 AIO00354.1 - 1.7e-32 112.3 11.1 1.7e-32 112.3 11.1 1.7 2 0 0 2 2 2 1 DHHC palmitoyltransferase UCH PF00443.29 AIO00355.1 - 1.7e-34 119.5 0.0 2.8e-34 118.8 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 AIO00355.1 - 9.3e-08 32.0 2.6 0.00049 19.8 2.8 2.3 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 AIO00355.1 - 0.16 12.3 9.9 0.21 11.9 1.1 4.2 3 0 0 3 3 3 0 Zn-finger in ubiquitin-hydrolases and other protein LSM PF01423.22 AIO00356.1 - 1.6e-15 56.5 0.1 1.8e-15 56.4 0.1 1.1 1 0 0 1 1 1 1 LSM domain AAA_28 PF13521.6 AIO00357.1 - 6.3e-19 68.8 0.0 1.3e-18 67.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain MeaB PF03308.16 AIO00357.1 - 0.017 14.1 0.0 0.028 13.4 0.0 1.3 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_30 PF13604.6 AIO00357.1 - 0.064 13.0 0.0 0.15 11.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain DAP3 PF10236.9 AIO00357.1 - 0.08 12.1 0.0 0.15 11.2 0.0 1.4 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 AAA_29 PF13555.6 AIO00357.1 - 0.17 11.6 0.0 0.4 10.5 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain zf-C3HC4_3 PF13920.6 AIO00358.1 - 3.7e-08 33.1 13.3 3.7e-08 33.1 13.3 3.8 3 1 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 AIO00358.1 - 0.00019 21.2 14.1 0.00019 21.2 14.1 3.2 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) EF-hand_7 PF13499.6 AIO00359.1 - 3.8e-06 27.3 1.3 0.0022 18.4 0.1 2.2 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 AIO00359.1 - 0.0018 18.1 0.1 0.007 16.2 0.1 2.0 2 0 0 2 2 2 1 EF-hand domain EF-hand_5 PF13202.6 AIO00359.1 - 0.016 14.7 0.2 0.033 13.7 0.2 1.6 1 0 0 1 1 1 0 EF hand EF-hand_1 PF00036.32 AIO00359.1 - 0.035 13.7 0.0 0.091 12.4 0.0 1.8 1 0 0 1 1 1 0 EF hand Phos_pyr_kin PF08543.12 AIO00360.1 - 1.2e-16 60.8 0.0 1.7e-16 60.4 0.0 1.2 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase PfkB PF00294.24 AIO00360.1 - 3.6e-08 33.1 1.0 8.9e-07 28.5 0.0 2.3 2 0 0 2 2 2 1 pfkB family carbohydrate kinase DUF2922 PF11148.8 AIO00360.1 - 0.17 11.6 0.0 0.37 10.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2922) Acetyltransf_7 PF13508.7 AIO00361.1 - 2.2e-05 24.8 0.0 0.00073 19.9 0.0 2.3 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 AIO00361.1 - 0.00018 21.7 0.0 0.00055 20.2 0.0 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 AIO00361.1 - 0.0009 19.2 0.0 0.019 14.9 0.0 2.6 2 1 1 3 3 3 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 AIO00361.1 - 0.0031 17.5 0.1 0.041 13.8 0.0 2.2 2 0 0 2 2 2 1 FR47-like protein Acetyltransf_9 PF13527.7 AIO00361.1 - 0.011 15.8 0.0 0.047 13.8 0.0 1.9 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Acetyltransf_13 PF13880.6 AIO00361.1 - 0.11 12.4 0.0 0.29 11.1 0.0 1.7 1 0 0 1 1 1 0 ESCO1/2 acetyl-transferase HAUS-augmin3 PF14932.6 AIO00363.1 - 0.0041 16.7 1.6 0.0041 16.7 1.6 3.3 3 1 1 4 4 4 1 HAUS augmin-like complex subunit 3 CENP-F_leu_zip PF10473.9 AIO00363.1 - 0.018 15.1 0.5 0.018 15.1 0.5 2.9 2 1 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Takusan PF04822.13 AIO00363.1 - 0.04 13.8 1.2 0.12 12.2 0.2 2.4 2 0 0 2 2 2 0 Takusan AAA_23 PF13476.6 AIO00363.1 - 0.046 14.2 6.8 3.4 8.1 6.8 2.2 1 1 0 1 1 1 0 AAA domain SAM_Exu PF18609.1 AIO00363.1 - 0.089 12.9 0.2 0.43 10.7 0.2 2.2 1 0 0 1 1 1 0 Exuperantia SAM-like domain Seryl_tRNA_N PF02403.22 AIO00363.1 - 0.12 12.6 0.2 0.12 12.6 0.2 3.4 4 0 0 4 4 4 0 Seryl-tRNA synthetase N-terminal domain GIT_CC PF16559.5 AIO00363.1 - 0.43 10.5 8.7 0.14 12.0 1.6 3.2 2 1 1 3 3 3 0 GIT coiled-coil Rho guanine nucleotide exchange factor Fib_alpha PF08702.10 AIO00363.1 - 0.44 10.7 4.1 4.3 7.5 0.1 3.4 3 1 0 3 3 3 0 Fibrinogen alpha/beta chain family Clathrin PF00637.20 AIO00364.1 - 1.6e-09 37.8 0.1 3.2e-08 33.5 0.5 2.3 2 0 0 2 2 2 1 Region in Clathrin and VPS LysM PF01476.20 AIO00364.1 - 0.0079 16.2 0.0 0.018 15.1 0.0 1.6 1 0 0 1 1 1 1 LysM domain zf-C3HC4_2 PF13923.6 AIO00364.1 - 0.013 15.4 4.5 0.038 13.8 4.5 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 AIO00364.1 - 0.018 15.3 2.5 0.05 13.9 2.5 1.7 1 0 0 1 1 1 0 RING-H2 zinc finger domain ANAPC4_WD40 PF12894.7 AIO00364.1 - 0.039 14.2 0.1 5 7.5 0.0 2.6 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain zf-RING_2 PF13639.6 AIO00364.1 - 0.044 14.1 5.2 0.14 12.5 5.2 2.0 1 0 0 1 1 1 0 Ring finger domain zf-ANAPC11 PF12861.7 AIO00364.1 - 0.053 13.6 0.9 0.2 11.7 0.9 2.0 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4 PF00097.25 AIO00364.1 - 0.13 12.1 4.0 0.34 10.8 4.0 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 AIO00364.1 - 0.76 9.5 12.7 0.013 15.1 2.9 2.9 3 0 0 3 3 3 0 Zinc-ribbon, C4HC2 type zf-RING_5 PF14634.6 AIO00364.1 - 0.96 9.5 8.1 0.23 11.5 3.8 2.2 2 0 0 2 2 2 0 zinc-RING finger domain zf-C3H2C3 PF17122.5 AIO00364.1 - 2.1 8.4 7.3 5.2 7.2 7.3 1.7 1 0 0 1 1 1 0 Zinc-finger Brix PF04427.18 AIO00365.1 - 4.9e-29 101.8 0.2 6.8e-29 101.4 0.2 1.2 1 0 0 1 1 1 1 Brix domain SNF2_N PF00176.23 AIO00366.1 - 1.6e-46 158.6 0.0 2.7e-46 157.9 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 AIO00366.1 - 1e-09 38.7 0.0 1.8e-09 37.9 0.0 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 AIO00366.1 - 6.8e-05 22.9 0.0 0.00017 21.6 0.0 1.7 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 AIO00366.1 - 0.034 13.4 0.0 0.061 12.5 0.0 1.3 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase IMUP PF15761.5 AIO00366.1 - 0.14 12.9 3.6 0.41 11.4 3.6 1.8 1 0 0 1 1 1 0 Immortalisation up-regulated protein ABC_tran PF00005.27 AIO00368.1 - 1.1e-18 68.1 1.1 6.4e-13 49.4 0.7 3.1 2 1 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 AIO00368.1 - 3.1e-10 40.4 0.7 8.6e-06 25.8 0.1 2.5 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 AIO00368.1 - 2.7e-05 23.7 1.2 0.24 10.8 0.1 3.1 3 0 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 AIO00368.1 - 0.00081 19.8 0.0 0.01 16.3 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain AAA_29 PF13555.6 AIO00368.1 - 0.0012 18.5 0.0 0.0025 17.5 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_23 PF13476.6 AIO00368.1 - 0.0026 18.3 0.0 0.028 14.9 0.0 2.0 2 0 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 AIO00368.1 - 0.0043 17.0 0.0 0.012 15.5 0.0 1.7 2 0 0 2 2 2 1 RsgA GTPase IstB_IS21 PF01695.17 AIO00368.1 - 0.018 14.8 0.7 5.7 6.6 0.0 3.1 3 0 0 3 3 3 0 IstB-like ATP binding protein Dynamin_N PF00350.23 AIO00368.1 - 0.027 14.5 0.1 0.049 13.7 0.1 1.4 1 0 0 1 1 1 0 Dynamin family AAA_15 PF13175.6 AIO00368.1 - 0.06 13.0 0.1 0.096 12.4 0.1 1.2 1 0 0 1 1 1 0 AAA ATPase domain AAA_24 PF13479.6 AIO00368.1 - 0.08 12.7 0.0 0.29 10.8 0.0 1.9 2 0 0 2 2 2 0 AAA domain T2SSE PF00437.20 AIO00368.1 - 0.13 11.3 0.0 0.21 10.6 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein FtsK_SpoIIIE PF01580.18 AIO00368.1 - 0.15 11.4 0.0 0.26 10.6 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_28 PF13521.6 AIO00368.1 - 0.15 12.3 0.8 0.48 10.7 0.1 2.1 2 0 0 2 2 2 0 AAA domain G-alpha PF00503.20 AIO00368.1 - 0.18 10.9 0.0 0.27 10.4 0.0 1.1 1 0 0 1 1 1 0 G-protein alpha subunit RabGAP-TBC PF00566.18 AIO00370.1 - 8.9e-36 123.6 0.9 1.3e-35 123.0 0.2 1.5 2 0 0 2 2 2 1 Rab-GTPase-TBC domain RIO1 PF01163.22 AIO00371.1 - 4.2e-45 153.7 0.0 9.1e-45 152.6 0.0 1.5 1 0 0 1 1 1 1 RIO1 family Rio2_N PF09202.11 AIO00371.1 - 6.6e-33 112.8 0.2 1.8e-31 108.2 0.3 2.4 2 0 0 2 2 2 1 Rio2, N-terminal APH PF01636.23 AIO00371.1 - 9.8e-10 38.8 0.0 1.7e-05 24.9 0.0 2.4 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 AIO00371.1 - 0.00041 19.7 1.4 0.014 14.8 0.0 3.1 3 1 0 3 3 3 1 Lipopolysaccharide kinase (Kdo/WaaP) family PSP1 PF04468.12 AIO00372.1 - 1.2e-13 51.2 0.2 1.9e-13 50.5 0.2 1.4 1 0 0 1 1 1 1 PSP1 C-terminal conserved region PLAC8 PF04749.17 AIO00373.1 - 2.5e-15 57.3 12.1 3.4e-15 56.8 12.1 1.2 1 0 0 1 1 1 1 PLAC8 family DUF1360 PF07098.11 AIO00373.1 - 4.2 7.4 7.1 0.12 12.4 1.2 1.6 2 1 0 2 2 2 0 Protein of unknown function (DUF1360) WD40 PF00400.32 AIO00374.1 - 8.6e-19 67.5 2.4 0.0006 20.6 0.2 7.1 7 0 0 7 7 7 4 WD domain, G-beta repeat Nup160 PF11715.8 AIO00374.1 - 0.0029 16.3 0.2 1.6 7.3 0.1 2.5 2 1 1 3 3 3 2 Nucleoporin Nup120/160 ANAPC4_WD40 PF12894.7 AIO00374.1 - 0.011 16.0 0.1 3 8.2 0.0 2.7 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain Kinesin PF00225.23 AIO00375.1 - 1.6e-83 280.4 0.4 1.6e-83 280.4 0.4 1.5 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 AIO00375.1 - 1.7e-17 63.7 1.1 3e-17 62.9 0.1 1.9 2 0 0 2 2 2 1 Microtubule binding AAA_16 PF13191.6 AIO00375.1 - 0.011 16.1 3.5 0.12 12.8 0.0 3.2 3 0 0 3 3 3 0 AAA ATPase domain Serine_protease PF18405.1 AIO00375.1 - 0.065 12.4 0.2 0.13 11.4 0.2 1.4 1 0 0 1 1 1 0 Gammaproteobacterial serine protease S1-P1_nuclease PF02265.16 AIO00376.1 - 1.8e-61 208.2 0.0 2.2e-61 207.9 0.0 1.1 1 0 0 1 1 1 1 S1/P1 Nuclease PseudoU_synth_2 PF00849.22 AIO00377.1 - 1.2e-32 113.3 0.0 4.5e-32 111.3 0.0 1.9 1 1 0 1 1 1 1 RNA pseudouridylate synthase DUF2109 PF09882.9 AIO00377.1 - 0.017 15.1 0.0 0.11 12.5 0.0 2.1 2 0 0 2 2 2 0 Predicted membrane protein (DUF2109) Rad17 PF03215.15 AIO00378.1 - 8.7e-05 22.5 0.0 0.00013 21.9 0.0 1.3 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_16 PF13191.6 AIO00378.1 - 0.03 14.7 0.4 0.15 12.5 0.1 2.3 1 1 0 2 2 2 0 AAA ATPase domain RuvB_N PF05496.12 AIO00378.1 - 0.039 13.7 0.0 0.07 12.9 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA PF00004.29 AIO00378.1 - 0.062 13.7 0.0 0.34 11.3 0.0 2.1 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Flavoprotein PF02441.19 AIO00379.1 - 1.8e-46 157.7 5.8 4.2e-44 150.1 0.2 3.1 4 0 0 4 4 4 2 Flavoprotein DUF1892 PF08987.10 AIO00379.1 - 0.18 12.0 0.0 0.33 11.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1892) PseudoU_synth_1 PF01416.20 AIO00380.1 - 3.6e-25 88.5 0.0 5e-24 84.9 0.0 2.3 2 0 0 2 2 2 1 tRNA pseudouridine synthase Pkinase PF00069.25 AIO00381.1 - 1.4e-34 119.6 0.0 8.8e-12 44.9 0.0 3.2 3 0 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.17 AIO00381.1 - 5.8e-16 58.6 0.0 1.5e-06 27.7 0.0 3.1 3 0 0 3 3 3 2 Protein tyrosine kinase Kinase-like PF14531.6 AIO00381.1 - 0.018 14.3 0.1 0.034 13.5 0.1 1.3 1 0 0 1 1 1 0 Kinase-like Pkinase_fungal PF17667.1 AIO00381.1 - 0.13 11.0 0.0 0.35 9.6 0.0 1.7 1 0 0 1 1 1 0 Fungal protein kinase DUF1796 PF08795.10 AIO00382.1 - 3e-67 225.8 0.0 4.1e-67 225.3 0.0 1.2 1 0 0 1 1 1 1 Putative papain-like cysteine peptidase (DUF1796) PH PF00169.29 AIO00383.1 - 1.9e-06 28.3 3.5 0.0026 18.2 0.3 2.7 2 1 0 2 2 2 2 PH domain Kelch_4 PF13418.6 AIO00383.1 - 0.00012 22.0 1.1 0.44 10.6 0.0 4.0 4 0 0 4 4 4 2 Galactose oxidase, central domain Kelch_5 PF13854.6 AIO00383.1 - 0.0047 16.9 0.5 11 6.1 0.0 4.1 4 0 0 4 4 4 1 Kelch motif Kelch_3 PF13415.6 AIO00383.1 - 0.0047 17.2 1.8 45 4.5 0.1 5.9 6 1 0 6 6 6 0 Galactose oxidase, central domain Kelch_6 PF13964.6 AIO00383.1 - 0.011 16.0 3.3 37 4.8 0.0 5.3 6 0 0 6 6 6 0 Kelch motif Kelch_1 PF01344.25 AIO00383.1 - 0.069 12.8 3.2 2.9 7.5 0.1 4.0 4 0 0 4 4 4 0 Kelch motif Actin PF00022.19 AIO00385.1 - 0.0028 16.3 0.0 0.0059 15.3 0.0 1.5 2 0 0 2 2 2 1 Actin Ferric_reduct PF01794.19 AIO00386.1 - 8.3e-15 55.0 10.9 8.3e-15 55.0 10.9 2.8 3 0 0 3 3 3 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 AIO00386.1 - 4.9e-12 46.2 0.0 2.4e-06 27.7 0.0 2.7 2 1 0 2 2 2 2 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 AIO00386.1 - 1.2e-08 35.0 0.0 2.7e-08 33.9 0.0 1.6 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_1 PF00175.21 AIO00386.1 - 0.0049 17.5 0.0 0.61 10.7 0.0 2.9 3 0 0 3 3 3 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 AIO00386.1 - 0.0096 16.2 0.0 0.025 14.9 0.0 1.8 1 1 0 1 1 1 1 Oxidoreductase FAD-binding domain DUF1077 PF06417.12 AIO00389.1 - 1.8e-35 121.5 1.2 2.2e-35 121.2 1.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1077) UbiA PF01040.18 AIO00389.1 - 0.0036 16.6 0.9 0.005 16.2 0.9 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family DUF4064 PF13273.6 AIO00389.1 - 0.0044 17.3 0.6 0.0069 16.6 0.6 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4064) HSP33 PF01430.19 AIO00390.1 - 3.4e-12 46.4 0.4 2.2e-05 24.0 0.1 2.9 3 0 0 3 3 3 2 Hsp33 protein AAA_2 PF07724.14 AIO00392.1 - 4.7e-08 33.3 0.0 7.5e-08 32.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 AIO00392.1 - 5.8e-06 26.6 0.0 4.2e-05 23.9 0.0 2.3 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.14 AIO00392.1 - 3.1e-05 24.0 0.0 9.8e-05 22.4 0.0 1.9 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) DUF2721 PF11026.8 AIO00392.1 - 0.00022 21.1 4.1 0.00062 19.7 4.1 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF2721) AAA PF00004.29 AIO00392.1 - 0.0043 17.5 0.0 0.0096 16.3 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 AIO00392.1 - 0.024 15.0 0.1 1.5 9.2 0.0 3.0 2 1 0 2 2 2 0 AAA ATPase domain NPR1_like_C PF12313.8 AIO00392.1 - 0.24 10.9 1.4 1.2 8.6 0.2 2.1 2 0 0 2 2 2 0 NPR1/NIM1 like defence protein C terminal Ras PF00071.22 AIO00393.1 - 2.2e-39 134.7 0.0 2.7e-39 134.4 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 AIO00393.1 - 1.6e-26 92.9 0.0 2.4e-26 92.3 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 AIO00393.1 - 3.1e-12 46.3 0.0 4.1e-12 45.9 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 AIO00393.1 - 0.00019 21.5 0.0 0.0003 20.9 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 AIO00393.1 - 0.00052 20.0 0.1 0.17 11.8 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase FeoB_N PF02421.18 AIO00393.1 - 0.0013 18.3 0.0 1.5 8.3 0.0 2.3 2 0 0 2 2 2 2 Ferrous iron transport protein B Gtr1_RagA PF04670.12 AIO00393.1 - 0.0015 17.9 0.0 0.0019 17.6 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region G-alpha PF00503.20 AIO00393.1 - 0.0047 16.1 0.0 0.71 9.0 0.0 2.3 1 1 1 2 2 2 2 G-protein alpha subunit AAA_16 PF13191.6 AIO00393.1 - 0.015 15.7 0.0 0.035 14.5 0.0 1.6 1 1 0 1 1 1 0 AAA ATPase domain PduV-EutP PF10662.9 AIO00393.1 - 0.073 12.8 0.0 0.23 11.2 0.0 1.8 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation APG6_N PF17675.1 AIO00395.1 - 0.028 15.0 29.8 0.12 12.9 14.5 2.2 2 0 0 2 2 2 0 Apg6 coiled-coil region ATG16 PF08614.11 AIO00395.1 - 0.13 12.5 35.9 0.035 14.3 7.4 2.5 1 1 2 3 3 3 0 Autophagy protein 16 (ATG16) Enkurin PF13864.6 AIO00395.1 - 0.17 12.3 17.3 0.042 14.3 7.0 2.4 2 0 0 2 2 2 0 Calmodulin-binding DUF4407 PF14362.6 AIO00395.1 - 1.7 7.9 16.5 1.5 8.1 8.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Fez1 PF06818.15 AIO00395.1 - 2.1 8.8 20.2 0.24 11.9 2.7 2.2 2 0 0 2 2 2 0 Fez1 BBS2_C PF14782.6 AIO00395.1 - 7.8 5.1 15.1 0.28 9.9 5.3 2.0 2 0 0 2 2 2 0 Ciliary BBSome complex subunit 2, C-terminal CLASP_N PF12348.8 AIO00398.1 - 5.1e-11 42.6 0.0 1.6e-06 27.8 0.0 3.6 3 0 0 3 3 3 2 CLASP N terminal HEAT PF02985.22 AIO00398.1 - 0.0048 17.0 6.3 3 8.3 0.1 6.3 6 0 0 6 6 6 1 HEAT repeat HEAT_2 PF13646.6 AIO00398.1 - 0.0082 16.5 8.9 0.4 11.1 0.0 5.4 5 0 0 5 5 5 1 HEAT repeats Cnd1 PF12717.7 AIO00398.1 - 0.034 14.2 1.6 1.9 8.5 0.0 3.4 3 0 0 3 3 3 0 non-SMC mitotic condensation complex subunit 1 NUC173 PF08161.12 AIO00398.1 - 0.093 12.4 0.1 0.57 9.8 0.1 2.5 2 0 0 2 2 2 0 NUC173 domain IFT46_B_C PF12317.8 AIO00399.1 - 1.6e-80 269.8 0.1 1.9e-80 269.6 0.1 1.1 1 0 0 1 1 1 1 Intraflagellar transport complex B protein 46 C terminal NOA36 PF06524.12 AIO00399.1 - 2.5 7.4 3.5 4.2 6.6 3.5 1.3 1 0 0 1 1 1 0 NOA36 protein Pkinase PF00069.25 AIO00400.1 - 1.2e-29 103.5 0.0 5.8e-28 98.0 0.0 2.9 3 1 0 3 3 3 1 Protein kinase domain Pkinase_Tyr PF07714.17 AIO00400.1 - 5.1e-08 32.5 0.0 1.7e-05 24.3 0.0 2.5 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 AIO00400.1 - 0.003 17.5 0.0 0.0082 16.1 0.0 1.7 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.6 AIO00400.1 - 0.14 11.5 0.0 0.57 9.5 0.0 1.9 3 0 0 3 3 3 0 Kinase-like DnaJ PF00226.31 AIO00401.1 - 7.9e-20 70.8 0.5 2e-19 69.4 0.1 1.9 2 0 0 2 2 2 1 DnaJ domain FAM199X PF15814.5 AIO00401.1 - 0.0091 15.1 1.2 0.025 13.7 1.2 1.7 1 0 0 1 1 1 1 Protein family FAM199X TGT PF01702.18 AIO00402.1 - 4.8e-124 414.0 0.0 7e-92 308.3 0.0 2.1 1 1 1 2 2 2 2 Queuine tRNA-ribosyltransferase ASH PF15780.5 AIO00403.1 - 1.3e-47 160.0 58.0 2e-06 27.9 0.0 31.7 36 1 0 36 36 35 9 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin PapD-like PF14874.6 AIO00403.1 - 8.5e-19 67.6 32.7 0.00044 20.4 0.0 14.2 17 0 0 17 17 16 4 Flagellar-associated PapD-like DUF1573 PF07610.11 AIO00403.1 - 9.2e-16 57.7 0.0 4.1 7.5 0.1 13.3 16 0 0 16 16 15 1 Protein of unknown function (DUF1573) Motile_Sperm PF00635.26 AIO00403.1 - 1.5e-12 47.3 7.8 4.6 7.1 0.0 13.4 16 0 0 16 16 16 1 MSP (Major sperm protein) domain TMEM131_like PF12371.8 AIO00403.1 - 6.7e-09 35.9 8.9 5.6 7.3 0.0 10.7 12 0 0 12 12 11 2 Transmembrane protein 131-like DUF5001 PF16392.5 AIO00403.1 - 1.4e-06 28.1 0.5 6.9 6.7 0.0 7.1 5 0 0 5 5 5 1 Ig-like domain MYCBPAP PF14646.6 AIO00403.1 - 0.0015 17.6 0.0 22 3.8 0.0 6.2 6 1 0 6 6 6 0 MYCBP-associated protein family AAA_33 PF13671.6 AIO00403.1 - 0.0046 17.1 0.0 0.016 15.4 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 AIO00403.1 - 0.018 15.3 0.0 0.049 13.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 AIO00403.1 - 0.038 13.3 0.0 0.08 12.2 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin fn3_5 PF06280.12 AIO00403.1 - 0.093 13.4 10.6 21 5.8 0.1 7.7 8 1 0 8 8 7 0 Fn3-like domain Trigger_C PF05698.14 AIO00403.1 - 0.48 10.4 1.8 0.9 9.5 1.8 1.3 1 0 0 1 1 1 0 Bacterial trigger factor protein (TF) C-terminus DUF756 PF05506.12 AIO00403.1 - 9 7.3 12.0 54 4.8 0.0 7.9 8 1 1 9 9 8 0 Domain of unknown function (DUF756) DUF3449 PF11931.8 AIO00404.1 - 4e-38 131.1 0.4 4e-38 131.1 0.4 2.3 2 1 0 2 2 2 1 Domain of unknown function (DUF3449) SF3A3 PF16837.5 AIO00404.1 - 9.2e-09 35.7 0.0 6.1e-08 33.1 0.0 2.3 2 0 0 2 2 2 1 Pre-mRNA-splicing factor SF3A3, of SF3a complex, Prp9 zf-RING_7 PF02591.15 AIO00404.1 - 0.19 12.0 0.0 22 5.4 0.0 2.8 2 0 0 2 2 2 0 C4-type zinc ribbon domain FYVE PF01363.21 AIO00406.1 - 4.9e-11 42.6 5.9 4.9e-11 42.6 5.9 2.4 2 0 0 2 2 2 1 FYVE zinc finger PI3_PI4_kinase PF00454.27 AIO00406.1 - 1.5e-09 38.1 0.4 1.3e-07 31.7 0.1 2.4 2 0 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase IBR PF01485.21 AIO00406.1 - 0.1 12.9 2.5 0.3 11.3 2.5 1.8 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain OrfB_Zn_ribbon PF07282.11 AIO00406.1 - 0.11 12.4 3.0 0.44 10.5 3.0 2.0 1 0 0 1 1 1 0 Putative transposase DNA-binding domain zf-ribbon_3 PF13248.6 AIO00406.1 - 0.49 9.9 2.2 5.3 6.6 2.2 2.5 1 1 0 1 1 1 0 zinc-ribbon domain MCR PF18509.1 AIO00409.1 - 0.078 12.6 0.7 0.46 10.1 0.1 2.2 2 0 0 2 2 2 0 Magnetochrome domain AAA_18 PF13238.6 AIO00410.1 - 1.4e-28 100.1 0.0 1.9e-28 99.6 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 AIO00410.1 - 4.5e-08 33.4 0.1 1.3e-05 25.3 0.1 2.3 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.6 AIO00410.1 - 5e-08 33.5 1.4 9e-08 32.6 0.3 2.0 2 1 0 2 2 1 1 AAA domain AAA PF00004.29 AIO00410.1 - 1.6e-05 25.3 0.4 2.8e-05 24.6 0.4 1.8 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.6 AIO00410.1 - 1.7e-05 25.1 2.3 3.9e-05 23.9 0.1 2.2 1 1 1 3 3 3 1 AAA domain dNK PF01712.19 AIO00410.1 - 0.00015 21.7 0.9 0.51 10.2 0.1 2.3 1 1 0 2 2 2 2 Deoxynucleoside kinase RuvB_N PF05496.12 AIO00410.1 - 0.00019 21.2 0.0 0.00032 20.5 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain SKI PF01202.22 AIO00410.1 - 0.00046 20.3 3.9 0.01 15.9 3.9 2.2 1 1 0 1 1 1 1 Shikimate kinase AAA_22 PF13401.6 AIO00410.1 - 0.0014 18.9 0.0 0.0038 17.5 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 AIO00410.1 - 0.0018 18.7 0.0 0.0021 18.5 0.0 1.5 1 1 0 1 1 1 1 AAA ATPase domain RNA_helicase PF00910.22 AIO00410.1 - 0.0026 18.1 0.0 0.0053 17.1 0.0 1.5 1 0 0 1 1 1 1 RNA helicase AAA_5 PF07728.14 AIO00410.1 - 0.0036 17.3 0.3 0.0084 16.1 0.1 1.8 1 1 0 2 2 2 1 AAA domain (dynein-related subfamily) ADK PF00406.22 AIO00410.1 - 0.0052 16.9 0.2 0.34 11.0 0.0 2.2 2 0 0 2 2 2 1 Adenylate kinase AAA_24 PF13479.6 AIO00410.1 - 0.0056 16.4 0.4 0.028 14.1 0.1 2.1 2 0 0 2 2 2 1 AAA domain Mg_chelatase PF01078.21 AIO00410.1 - 0.0058 16.0 0.2 0.027 13.9 0.0 1.9 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI DUF2075 PF09848.9 AIO00410.1 - 0.0081 15.4 0.1 0.012 14.9 0.0 1.4 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) Cytidylate_kin PF02224.18 AIO00410.1 - 0.01 15.6 1.8 0.56 9.9 0.0 2.1 1 1 1 2 2 2 0 Cytidylate kinase ATPase PF06745.13 AIO00410.1 - 0.012 15.0 0.9 0.018 14.4 0.1 1.6 2 0 0 2 2 2 0 KaiC TIP49 PF06068.13 AIO00410.1 - 0.013 14.7 0.0 0.013 14.7 0.0 1.2 1 0 0 1 1 1 0 TIP49 P-loop domain NTPase_1 PF03266.15 AIO00410.1 - 0.015 15.2 0.2 0.046 13.6 0.0 2.0 2 1 0 2 2 2 0 NTPase Zeta_toxin PF06414.12 AIO00410.1 - 0.018 14.3 0.0 0.032 13.5 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin KTI12 PF08433.10 AIO00410.1 - 0.02 14.4 0.3 0.088 12.2 0.0 1.9 2 0 0 2 2 2 0 Chromatin associated protein KTI12 IstB_IS21 PF01695.17 AIO00410.1 - 0.031 14.0 0.0 0.064 13.0 0.0 1.6 2 0 0 2 2 1 0 IstB-like ATP binding protein Parvo_NS1 PF01057.17 AIO00410.1 - 0.034 13.2 0.1 0.07 12.2 0.0 1.5 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 Sigma54_activat PF00158.26 AIO00410.1 - 0.04 13.6 0.2 0.093 12.4 0.1 1.6 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_26 PF13500.6 AIO00410.1 - 0.041 13.7 0.0 0.15 11.9 0.0 1.8 2 0 0 2 2 2 0 AAA domain Torsin PF06309.11 AIO00410.1 - 0.064 13.4 0.0 0.13 12.4 0.0 1.5 1 0 0 1 1 1 0 Torsin KAP_NTPase PF07693.14 AIO00410.1 - 0.072 12.3 0.0 0.082 12.1 0.0 1.2 1 1 0 1 1 1 0 KAP family P-loop domain ABC_tran PF00005.27 AIO00410.1 - 0.072 13.6 2.1 0.57 10.7 2.1 2.1 1 1 0 1 1 1 0 ABC transporter AAA_19 PF13245.6 AIO00410.1 - 0.09 13.1 3.0 0.22 11.8 3.0 2.0 1 1 0 1 1 1 0 AAA domain Sars6 PF12133.8 AIO00410.1 - 0.092 12.7 0.0 0.2 11.6 0.0 1.6 1 0 0 1 1 1 0 Open reading frame 6 from SARS coronavirus AAA_7 PF12775.7 AIO00410.1 - 0.098 12.2 0.0 0.16 11.5 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_3 PF07726.11 AIO00410.1 - 0.1 12.5 0.0 0.21 11.5 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) APS_kinase PF01583.20 AIO00410.1 - 0.1 12.5 0.0 0.24 11.3 0.0 1.7 2 0 0 2 2 2 0 Adenylylsulphate kinase Thymidylate_kin PF02223.17 AIO00410.1 - 0.12 12.0 2.2 8.2 6.1 0.3 2.5 2 1 1 3 3 3 0 Thymidylate kinase AAA_23 PF13476.6 AIO00410.1 - 0.15 12.5 0.6 0.32 11.5 0.6 1.6 1 1 0 1 1 1 0 AAA domain Sigma54_activ_2 PF14532.6 AIO00410.1 - 0.16 12.1 0.0 0.29 11.2 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain CPT PF07931.12 AIO00410.1 - 0.16 11.8 2.6 1.6 8.5 0.0 2.7 2 1 1 3 3 3 0 Chloramphenicol phosphotransferase-like protein AAA_29 PF13555.6 AIO00410.1 - 0.2 11.5 0.1 0.33 10.7 0.1 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain Elf1 PF05129.13 AIO00412.1 - 0.24 11.4 3.6 0.48 10.5 3.6 1.4 1 0 0 1 1 1 0 Transcription elongation factor Elf1 like CoA_trans PF01144.23 AIO00413.1 - 7.4e-74 247.8 0.0 1.1e-47 162.3 0.0 2.0 2 0 0 2 2 2 2 Coenzyme A transferase Mal_decarbox_Al PF16957.5 AIO00413.1 - 0.11 10.8 0.0 0.14 10.4 0.0 1.1 1 0 0 1 1 1 0 Malonate decarboxylase, alpha subunit, transporter PseudoU_synth_2 PF00849.22 AIO00415.1 - 2.5e-18 66.7 0.1 1.2e-08 35.2 0.0 2.6 2 0 0 2 2 2 2 RNA pseudouridylate synthase S4 PF01479.25 AIO00415.1 - 0.0018 18.0 0.0 0.0065 16.2 0.0 1.9 2 0 0 2 2 2 1 S4 domain ArsA_ATPase PF02374.15 AIO00415.1 - 0.21 10.7 0.0 0.31 10.2 0.0 1.2 1 0 0 1 1 1 0 Anion-transporting ATPase TPR_MLP1_2 PF07926.12 AIO00416.1 - 0.0013 18.8 19.8 0.015 15.4 1.5 3.3 3 0 0 3 3 3 2 TPR/MLP1/MLP2-like protein DUF745 PF05335.13 AIO00416.1 - 0.019 14.7 1.2 0.019 14.7 1.2 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF745) DUF1154 PF06631.11 AIO00416.1 - 0.97 9.5 5.5 4.8 7.3 5.0 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1154) Syntaxin-6_N PF09177.11 AIO00416.1 - 1.2 9.8 11.2 0.19 12.3 0.7 3.3 3 0 0 3 3 3 0 Syntaxin 6, N-terminal DUF641 PF04859.12 AIO00416.1 - 3.8 7.9 14.0 0.44 10.9 5.5 3.1 3 0 0 3 3 3 0 Plant protein of unknown function (DUF641) BILBO1_N PF18281.1 AIO00417.1 - 2.9e-20 72.5 0.1 1e-19 70.8 0.0 1.9 2 0 0 2 2 2 1 BILBO1 N-terminal domain zf-C2H2_2 PF12756.7 AIO00418.1 - 1.1e-20 73.8 6.4 3.8e-14 52.9 0.4 2.3 2 0 0 2 2 2 2 C2H2 type zinc-finger (2 copies) zf-Di19 PF05605.12 AIO00418.1 - 4e-05 23.8 11.4 0.0096 16.2 0.2 4.3 3 1 0 4 4 4 2 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_4 PF13894.6 AIO00418.1 - 0.00012 22.6 8.5 0.098 13.6 0.1 4.4 4 0 0 4 4 4 1 C2H2-type zinc finger Clr5 PF14420.6 AIO00418.1 - 0.12 12.6 0.3 1.3 9.3 0.0 2.7 3 0 0 3 3 3 0 Clr5 domain zf-C2H2_12 PF18658.1 AIO00418.1 - 0.22 11.1 0.1 0.22 11.1 0.1 2.8 3 0 0 3 3 3 0 Zinc-finger C2H2-type Glycos_transf_1 PF00534.20 AIO00418.1 - 0.24 10.9 0.0 0.62 9.6 0.0 1.6 1 1 1 2 2 2 0 Glycosyl transferases group 1 zf-C2H2 PF00096.26 AIO00418.1 - 1.7 9.3 9.9 14 6.4 0.0 4.5 4 1 0 4 4 4 0 Zinc finger, C2H2 type zf-BED PF02892.15 AIO00418.1 - 8 6.6 8.8 15 5.7 0.0 4.0 3 1 0 3 3 3 0 BED zinc finger PC_rep PF01851.22 AIO00419.1 - 0.015 15.7 11.5 8.2 7.1 0.0 6.1 6 0 0 6 6 6 0 Proteasome/cyclosome repeat IFT20 PF14931.6 AIO00420.1 - 7.2e-35 119.7 5.0 8e-35 119.6 5.0 1.0 1 0 0 1 1 1 1 Intraflagellar transport complex B, subunit 20 ISG65-75 PF11727.8 AIO00420.1 - 0.017 14.4 1.2 0.021 14.1 1.2 1.1 1 0 0 1 1 1 0 Invariant surface glycoprotein VQ PF05678.14 AIO00420.1 - 0.039 13.4 4.5 0.72 9.4 0.1 2.9 3 0 0 3 3 3 0 VQ motif Mannosyl_trans PF05007.13 AIO00421.1 - 6e-83 278.7 13.2 8.5e-83 278.2 13.2 1.2 1 0 0 1 1 1 1 Mannosyltransferase (PIG-M) GT87 PF09594.10 AIO00421.1 - 1.3e-10 41.4 12.2 1.3e-10 41.4 12.2 2.7 1 1 0 2 2 2 1 Glycosyltransferase family 87 PIG-U PF06728.13 AIO00421.1 - 2.2e-08 33.6 16.4 6.1e-08 32.1 16.1 1.8 1 1 0 1 1 1 1 GPI transamidase subunit PIG-U Peptidase_C2 PF00648.21 AIO00422.1 - 5.9e-26 91.2 0.0 5.8e-13 48.5 0.0 4.1 4 0 0 4 4 4 3 Calpain family cysteine protease LRR_6 PF13516.6 AIO00422.1 - 0.0041 17.0 1.8 23 5.4 0.0 3.6 3 0 0 3 3 3 2 Leucine Rich repeat Calpain_III PF01067.22 AIO00422.1 - 0.0051 17.1 0.0 1.4 9.1 0.0 2.6 2 0 0 2 2 2 2 Calpain large subunit, domain III LRR_1 PF00560.33 AIO00422.1 - 0.12 13.0 3.8 50 5.0 0.2 4.1 3 0 0 3 3 3 0 Leucine Rich Repeat LRR_4 PF12799.7 AIO00422.1 - 0.5 10.9 3.9 18 6.0 0.7 2.6 1 1 1 2 2 2 0 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 AIO00422.1 - 2.7 7.8 4.8 34 4.3 0.5 2.8 2 1 0 2 2 2 0 Leucine rich repeat Cytochrom_B561 PF03188.16 AIO00423.1 - 1.1e-12 48.3 3.9 1.2e-10 41.7 1.9 2.3 2 0 0 2 2 2 2 Eukaryotic cytochrome b561 zf-RING_UBOX PF13445.6 AIO00424.1 - 0.00059 19.8 7.7 0.0019 18.2 7.7 1.9 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 AIO00424.1 - 0.0025 17.7 6.7 0.0025 17.7 6.7 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 AIO00424.1 - 0.0084 16.0 4.9 0.0084 16.0 4.9 2.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) NFACT-R_1 PF05670.13 AIO00426.1 - 1.2e-43 148.2 0.0 1.7e-43 147.7 0.0 1.2 1 0 0 1 1 1 1 NFACT protein RNA binding domain TcdA_TcdB PF12919.7 AIO00426.1 - 1.2 8.4 7.4 0.54 9.5 0.9 2.0 1 1 1 2 2 2 0 TcdA/TcdB catalytic glycosyltransferase domain NACHT PF05729.12 AIO00427.1 - 0.01 15.8 0.1 0.03 14.2 0.1 1.9 1 1 0 1 1 1 0 NACHT domain AAA_22 PF13401.6 AIO00427.1 - 0.023 15.0 0.0 0.18 12.0 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 AIO00427.1 - 0.038 14.4 0.1 0.1 13.0 0.1 1.9 1 1 0 1 1 1 0 AAA ATPase domain T2SSE PF00437.20 AIO00427.1 - 0.072 12.1 0.0 0.22 10.6 0.0 1.8 1 0 0 1 1 1 0 Type II/IV secretion system protein Fe-ADH PF00465.19 AIO00428.1 - 3.5e-110 368.3 0.2 3.9e-110 368.1 0.2 1.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.6 AIO00428.1 - 3.1e-18 66.4 0.2 4.6e-11 42.9 0.0 2.1 2 0 0 2 2 2 2 Iron-containing alcohol dehydrogenase DUF1664 PF07889.12 AIO00429.1 - 0.00013 22.0 1.7 0.00029 20.9 1.7 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1664) ARA70 PF12489.8 AIO00429.1 - 0.023 14.9 3.0 0.094 12.9 1.6 2.5 3 0 0 3 3 3 0 Nuclear coactivator FlgN PF05130.12 AIO00429.1 - 0.044 14.3 9.0 0.029 14.9 5.5 2.4 3 0 0 3 3 3 0 FlgN protein Baculo_PEP_C PF04513.12 AIO00429.1 - 0.054 13.5 2.0 0.13 12.3 2.0 1.5 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Exonuc_VII_L PF02601.15 AIO00429.1 - 0.058 12.9 2.8 0.039 13.5 0.5 1.9 2 0 0 2 2 2 0 Exonuclease VII, large subunit DUF4164 PF13747.6 AIO00429.1 - 0.11 12.8 0.4 0.11 12.8 0.4 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4164) Salp15 PF12115.8 AIO00429.1 - 0.12 12.8 1.3 0.3 11.5 1.2 1.8 1 1 0 1 1 1 0 Salivary protein of 15kDa inhibits CD4+ T cell activation DUF4709 PF15821.5 AIO00429.1 - 0.23 11.8 2.7 0.56 10.5 2.7 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4709) Apolipoprotein PF01442.18 AIO00429.1 - 0.53 10.1 8.5 0.23 11.3 4.9 2.2 2 0 0 2 2 2 0 Apolipoprotein A1/A4/E domain RsfS PF02410.15 AIO00431.1 - 2.3e-15 56.8 0.6 3.2e-15 56.4 0.6 1.2 1 0 0 1 1 1 1 Ribosomal silencing factor during starvation Pkinase PF00069.25 AIO00432.1 - 2.6e-53 181.1 0.2 5.6e-39 134.1 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 AIO00432.1 - 1.2e-35 123.1 0.1 1.5e-28 99.8 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Beta_helix PF13229.6 AIO00432.1 - 1.2e-29 103.2 6.8 3.4e-14 53.0 4.8 2.5 1 1 1 2 2 2 2 Right handed beta helix region NosD PF05048.13 AIO00432.1 - 1.2e-24 86.9 0.8 6.8e-14 51.7 0.8 2.5 1 1 1 2 2 2 2 Periplasmic copper-binding protein (NosD) Kinase-like PF14531.6 AIO00432.1 - 3.2e-05 23.4 0.0 6.5e-05 22.4 0.0 1.5 1 0 0 1 1 1 1 Kinase-like DUF1565 PF07602.11 AIO00432.1 - 0.0011 18.3 5.6 0.1 11.9 3.5 2.4 1 1 1 2 2 2 2 Protein of unknown function (DUF1565) Pkinase_fungal PF17667.1 AIO00432.1 - 0.091 11.5 0.0 0.14 10.9 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase APH PF01636.23 AIO00432.1 - 0.13 12.2 0.0 0.32 10.9 0.0 1.6 2 0 0 2 2 2 0 Phosphotransferase enzyme family Patatin PF01734.22 AIO00433.1 - 1.2e-22 81.1 1.0 1.7e-22 80.6 0.0 1.8 2 0 0 2 2 2 1 Patatin-like phospholipase DUF3336 PF11815.8 AIO00433.1 - 1.4e-07 31.3 0.0 2.5e-07 30.5 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3336) WD40 PF00400.32 AIO00434.1 - 4.6e-07 30.4 9.4 0.00052 20.8 0.1 6.2 7 0 0 7 7 7 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 AIO00434.1 - 0.017 15.4 0.0 5 7.5 0.0 4.3 5 1 0 5 5 5 0 Anaphase-promoting complex subunit 4 WD40 domain IBR PF01485.21 AIO00436.1 - 7.7e-13 48.5 25.8 2.1e-08 34.3 14.3 4.3 3 1 1 4 4 4 2 IBR domain, a half RING-finger domain zf-RING_5 PF14634.6 AIO00436.1 - 0.022 14.7 12.5 0.022 14.7 12.5 4.1 3 1 1 4 4 4 0 zinc-RING finger domain MctB PF11382.8 AIO00436.1 - 0.026 14.2 0.1 0.044 13.5 0.1 1.4 1 0 0 1 1 1 0 Copper transport outer membrane protein, MctB zf-RING_2 PF13639.6 AIO00436.1 - 2.2 8.7 46.4 0.04 14.3 13.4 4.0 2 1 1 3 3 3 0 Ring finger domain zf-C3HC4 PF00097.25 AIO00436.1 - 8 6.4 41.6 0.12 12.2 10.6 3.7 3 1 1 4 4 4 0 Zinc finger, C3HC4 type (RING finger) RRM_1 PF00076.22 AIO00437.1 - 3e-22 78.2 0.0 5.6e-12 45.3 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.22 AIO00438.1 - 1.5e-25 88.8 0.8 1e-14 54.1 0.1 3.3 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 AIO00438.1 - 0.02 15.0 0.0 0.55 10.4 0.0 2.7 2 1 0 2 2 2 0 RNA recognition motif RRM_Rrp7 PF17799.1 AIO00438.1 - 0.028 14.2 0.1 0.053 13.3 0.1 1.4 1 0 0 1 1 1 0 Rrp7 RRM-like N-terminal domain zf-CCCH PF00642.24 AIO00439.1 - 1.6e-07 31.0 0.4 2.3e-07 30.5 0.4 1.2 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 AIO00439.1 - 8.6e-07 28.6 0.8 1.2e-06 28.2 0.8 1.2 1 0 0 1 1 1 1 CCCH-type zinc finger zf_CCCH_4 PF18345.1 AIO00439.1 - 7.6e-05 22.6 0.6 0.00023 21.1 0.6 1.8 1 1 0 1 1 1 1 Zinc finger domain zf-CCCH_2 PF14608.6 AIO00439.1 - 0.00098 19.5 0.7 0.0016 18.8 0.7 1.3 1 0 0 1 1 1 1 RNA-binding, Nab2-type zinc finger Torus PF16131.5 AIO00439.1 - 0.11 13.2 0.0 0.16 12.7 0.0 1.3 1 0 0 1 1 1 0 Torus domain zf-CCCH_3 PF15663.5 AIO00439.1 - 0.14 12.4 0.1 0.26 11.5 0.1 1.4 1 0 0 1 1 1 0 Zinc-finger containing family GYF_2 PF14237.6 AIO00440.1 - 3.4e-18 65.2 0.2 9.6e-18 63.7 0.2 1.9 1 0 0 1 1 1 1 GYF domain 2 DnaJ PF00226.31 AIO00440.1 - 6.2e-14 51.9 0.3 1.4e-13 50.8 0.3 1.6 1 0 0 1 1 1 1 DnaJ domain HEAT PF02985.22 AIO00440.1 - 0.045 14.0 2.1 28 5.3 0.1 5.2 5 0 0 5 5 5 0 HEAT repeat DUF155 PF02582.14 AIO00441.1 - 3.8e-20 72.7 0.0 1.2e-19 71.1 0.0 1.8 2 0 0 2 2 2 1 Uncharacterised ACR, YagE family COG1723 Mito_carr PF00153.27 AIO00443.1 - 2e-09 37.2 7.0 0.12 12.3 0.5 5.2 4 1 0 4 4 4 4 Mitochondrial carrier protein CytB6-F_Fe-S PF08802.10 AIO00443.1 - 0.016 15.2 0.5 0.051 13.6 0.5 1.9 1 0 0 1 1 1 0 Cytochrome B6-F complex Fe-S subunit zf-C2H2_2 PF12756.7 AIO00444.1 - 1e-25 90.0 10.2 3.4e-19 69.1 1.6 3.2 3 0 0 3 3 3 2 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.8 AIO00444.1 - 4.5e-12 45.9 5.6 3.5e-07 30.3 0.1 4.0 3 1 0 3 3 3 3 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 AIO00444.1 - 1.2e-08 35.1 11.2 4.7e-05 23.6 1.0 3.7 3 1 0 3 3 3 2 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 AIO00444.1 - 2.1e-07 30.8 8.6 0.0017 18.3 0.7 3.6 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_4 PF13894.6 AIO00444.1 - 6.4e-07 29.7 14.1 0.00079 20.1 0.6 4.5 4 0 0 4 4 4 2 C2H2-type zinc finger zf-C2H2 PF00096.26 AIO00444.1 - 7e-05 23.1 19.0 0.0062 16.9 1.2 4.4 4 0 0 4 4 4 2 Zinc finger, C2H2 type zf-C2H2_12 PF18658.1 AIO00444.1 - 0.00073 19.1 9.2 0.0069 15.9 0.2 3.6 2 1 1 3 3 3 2 Zinc-finger C2H2-type Viral_DNA_bp PF00747.17 AIO00444.1 - 0.0033 14.7 0.3 0.0041 14.4 0.3 1.2 1 0 0 1 1 1 1 ssDNA binding protein zf_C2H2_ZHX PF18387.1 AIO00444.1 - 0.018 14.6 16.0 2.5 7.8 0.3 4.6 4 0 0 4 4 4 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-LYAR PF08790.11 AIO00444.1 - 0.12 12.3 0.5 0.12 12.3 0.5 2.0 2 0 0 2 2 2 0 LYAR-type C2HC zinc finger zf-BED PF02892.15 AIO00444.1 - 1.7 8.7 12.1 2.3 8.3 0.0 3.8 4 0 0 4 4 4 0 BED zinc finger OTT_1508_deam PF14441.6 AIO00444.1 - 9 6.4 6.5 4.5 7.3 0.1 3.1 4 0 0 4 4 4 0 OTT_1508-like deaminase PhoLip_ATPase_C PF16212.5 AIO00445.1 - 1.1e-39 136.7 15.2 1.1e-39 136.7 15.2 2.0 3 0 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 AIO00445.1 - 1.8e-19 69.2 3.5 5.2e-19 67.7 3.5 1.8 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Hydrolase PF00702.26 AIO00445.1 - 2.5e-09 37.7 0.1 0.00029 21.2 0.4 3.1 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 AIO00445.1 - 3.1e-07 30.4 0.0 9.8e-07 28.8 0.0 1.9 2 0 0 2 2 2 1 Cation transport ATPase (P-type) E1-E2_ATPase PF00122.20 AIO00445.1 - 4.5e-06 26.3 0.0 2.5e-05 23.9 0.0 2.2 1 1 0 1 1 1 1 E1-E2 ATPase Hydrolase_3 PF08282.12 AIO00445.1 - 0.056 13.2 0.0 0.13 11.9 0.0 1.6 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase LRR_4 PF12799.7 AIO00446.1 - 5.1e-17 61.7 8.6 3.7e-05 24.0 0.7 6.9 4 2 3 7 7 7 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 AIO00446.1 - 7e-07 28.9 20.5 0.00099 18.8 0.2 6.6 5 2 2 8 8 8 4 Leucine rich repeat LRR_9 PF14580.6 AIO00446.1 - 0.00057 19.4 0.1 0.051 13.1 0.0 2.9 2 0 0 2 2 2 1 Leucine-rich repeat LRR_6 PF13516.6 AIO00446.1 - 0.022 14.8 4.7 82 3.7 0.0 5.9 6 0 0 6 6 6 0 Leucine Rich repeat LRR_1 PF00560.33 AIO00446.1 - 0.084 13.5 9.8 1.1e+02 4.0 0.0 6.9 7 1 0 7 7 7 0 Leucine Rich Repeat TetR_C_13 PF16925.5 AIO00446.1 - 3 7.8 6.2 7.3 6.6 0.2 3.1 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain TTL PF03133.15 AIO00447.1 - 1.8e-48 165.2 0.0 1.1e-29 103.6 0.0 3.1 3 0 0 3 3 3 3 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 AIO00447.1 - 5.1e-07 29.2 0.0 0.015 14.6 0.0 2.5 2 1 0 2 2 2 2 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 AIO00447.1 - 8.8e-07 28.4 0.0 0.034 13.4 0.0 2.4 2 0 0 2 2 2 2 Sugar-transfer associated ATP-grasp Dala_Dala_lig_C PF07478.13 AIO00447.1 - 0.046 13.3 0.2 0.13 11.8 0.1 1.7 2 0 0 2 2 2 0 D-ala D-ala ligase C-terminus DEAD PF00270.29 AIO00448.1 - 1.1e-13 51.4 0.0 2.2e-13 50.3 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 AIO00448.1 - 5.8e-12 45.9 0.1 1.6e-11 44.5 0.1 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF742 PF05331.11 AIO00448.1 - 0.012 15.4 0.1 0.045 13.6 0.1 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF742) HTH_24 PF13412.6 AIO00448.1 - 0.13 11.8 0.0 0.4 10.3 0.0 1.8 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding Spc7 PF08317.11 AIO00449.1 - 0.65 8.8 6.4 1.2 8.0 6.4 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein SET PF00856.28 AIO00451.1 - 5.6e-07 30.1 0.0 1.2e-06 29.0 0.0 1.6 1 1 0 1 1 1 1 SET domain Dzip-like_N PF13815.6 AIO00453.1 - 0.034 14.1 0.3 0.089 12.8 0.3 1.8 1 0 0 1 1 1 0 Iguana/Dzip1-like DAZ-interacting protein N-terminal zf_Hakai PF18408.1 AIO00453.1 - 0.054 13.2 0.6 0.14 11.9 0.6 1.7 1 0 0 1 1 1 0 C2H2 Hakai zinc finger domain zf-C2H2_4 PF13894.6 AIO00453.1 - 0.13 13.1 0.2 0.59 11.1 0.2 2.2 1 0 0 1 1 1 0 C2H2-type zinc finger DUF3357 PF11837.8 AIO00453.1 - 0.52 10.8 3.8 3.2 8.3 1.0 3.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3357) DUF4169 PF13770.6 AIO00453.1 - 2.3 8.6 6.4 12 6.3 0.7 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4169) Pyridoxal_deC PF00282.19 AIO00454.1 - 6e-17 61.4 0.0 9.5e-17 60.8 0.0 1.3 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.19 AIO00454.1 - 5.4e-10 38.8 0.0 2.3e-09 36.7 0.0 2.0 1 1 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 AIO00454.1 - 0.0037 16.6 0.0 0.0056 16.0 0.0 1.1 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family CooT PF10133.9 AIO00454.1 - 0.12 12.6 0.0 0.3 11.4 0.0 1.7 1 0 0 1 1 1 0 CO dehydrogenase accessory protein CooT zf-C3HC4_4 PF15227.6 AIO00455.1 - 2e-09 37.4 7.3 2e-09 37.4 7.3 3.8 3 1 1 4 4 4 1 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.25 AIO00455.1 - 5.7e-09 35.7 7.0 5.7e-09 35.7 7.0 3.3 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 AIO00455.1 - 1.8e-08 34.1 6.3 1.8e-08 34.1 6.3 3.3 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 AIO00455.1 - 5.1e-08 32.8 4.6 5.1e-08 32.8 4.6 3.1 3 0 0 3 3 3 1 RING-type zinc-finger zf-B_box PF00643.24 AIO00455.1 - 1.2e-07 31.8 23.2 1.8e-06 28.0 7.7 4.9 5 0 0 5 5 5 2 B-box zinc finger zf-RING_5 PF14634.6 AIO00455.1 - 2.9e-06 27.1 6.4 2.9e-06 27.1 6.4 3.7 3 0 0 3 3 3 1 zinc-RING finger domain zf-RING_2 PF13639.6 AIO00455.1 - 4.5e-06 26.9 6.0 4.5e-06 26.9 6.0 3.6 3 0 0 3 3 3 1 Ring finger domain DUF1690 PF07956.11 AIO00455.1 - 0.0098 16.3 2.2 0.018 15.4 2.0 1.5 1 1 0 1 1 1 1 Protein of Unknown function (DUF1690) Flg_hook PF02120.16 AIO00455.1 - 0.036 13.9 0.5 0.036 13.9 0.5 2.3 2 0 0 2 2 2 0 Flagellar hook-length control protein FliK Apolipoprotein PF01442.18 AIO00455.1 - 0.056 13.3 8.2 0.12 12.3 8.2 1.4 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain Arf PF00025.21 AIO00456.1 - 1e-47 161.8 0.0 1.1e-47 161.7 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 AIO00456.1 - 3.6e-17 62.4 0.0 4.6e-17 62.0 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.22 AIO00456.1 - 1.3e-09 37.9 0.0 1.7e-09 37.5 0.0 1.1 1 0 0 1 1 1 1 Ras family G-alpha PF00503.20 AIO00456.1 - 1.6e-09 37.4 0.0 2.6e-05 23.6 0.0 2.2 1 1 1 2 2 2 2 G-protein alpha subunit MMR_HSR1 PF01926.23 AIO00456.1 - 2e-09 37.5 0.0 2.7e-09 37.1 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Roc PF08477.13 AIO00456.1 - 8.6e-09 35.7 0.0 1.3e-08 35.1 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Gtr1_RagA PF04670.12 AIO00456.1 - 2.5e-05 23.7 0.0 4.8e-05 22.8 0.0 1.4 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_18 PF13238.6 AIO00456.1 - 0.0019 18.7 0.0 0.0032 18.0 0.0 1.5 1 1 1 2 2 2 1 AAA domain FeoB_N PF02421.18 AIO00456.1 - 0.0023 17.5 0.1 0.0046 16.5 0.1 1.6 1 1 0 1 1 1 1 Ferrous iron transport protein B TniB PF05621.11 AIO00456.1 - 0.0055 16.1 0.0 0.0071 15.8 0.0 1.2 1 0 0 1 1 1 1 Bacterial TniB protein AAA_24 PF13479.6 AIO00456.1 - 0.0062 16.3 0.0 0.0083 15.9 0.0 1.2 1 0 0 1 1 1 1 AAA domain MeaB PF03308.16 AIO00456.1 - 0.014 14.4 0.0 0.11 11.4 0.0 1.9 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB NOG1 PF06858.14 AIO00456.1 - 0.015 15.1 0.1 0.026 14.3 0.1 1.4 1 0 0 1 1 1 0 Nucleolar GTP-binding protein 1 (NOG1) GTP_EFTU PF00009.27 AIO00456.1 - 0.06 12.9 0.3 1.9 8.0 0.0 2.1 1 1 1 2 2 2 0 Elongation factor Tu GTP binding domain DLIC PF05783.11 AIO00456.1 - 0.17 10.7 0.0 0.29 9.9 0.0 1.3 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) FtsK_SpoIIIE PF01580.18 AIO00456.1 - 0.19 11.0 0.1 3.7 6.8 0.0 2.0 2 0 0 2 2 2 0 FtsK/SpoIIIE family Anillin_N PF16018.5 AIO00457.1 - 0.093 13.3 0.2 0.093 13.3 0.2 3.6 3 1 0 3 3 3 0 Anillin N-terminus HIP1_clath_bdg PF16515.5 AIO00457.1 - 7.3 7.3 33.6 0.19 12.4 0.9 3.4 2 1 1 3 3 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 OpgC_C PF10129.9 AIO00459.1 - 0.0062 15.5 2.5 0.0083 15.0 2.5 1.2 1 0 0 1 1 1 1 OpgC protein CLP1_P PF16575.5 AIO00460.1 - 3.4e-36 124.8 0.0 5e-36 124.3 0.0 1.2 1 0 0 1 1 1 1 mRNA cleavage and polyadenylation factor CLP1 P-loop Clp1 PF06807.14 AIO00460.1 - 0.0027 18.1 0.1 0.009 16.4 0.0 1.9 2 0 0 2 2 2 1 Pre-mRNA cleavage complex II protein Clp1 CLP1_N PF16573.5 AIO00460.1 - 0.003 17.7 0.0 0.0058 16.8 0.0 1.4 1 0 0 1 1 1 1 N-terminal beta-sandwich domain of polyadenylation factor PTH2 PF01981.16 AIO00461.1 - 7.2e-22 77.9 0.1 9.9e-22 77.4 0.1 1.2 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase PTH2 CnrY PF17524.2 AIO00461.1 - 0.08 13.2 0.3 0.15 12.3 0.3 1.4 1 0 0 1 1 1 0 Anti-sigma factor CnrY DUF5632 PF18646.1 AIO00462.1 - 0.055 13.5 0.0 0.19 11.8 0.0 1.9 1 0 0 1 1 1 0 Family of unknown function (DUF5632) TPR_2 PF07719.17 AIO00463.1 - 2.3e-05 24.2 0.1 0.13 12.5 0.0 2.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 AIO00463.1 - 0.0044 16.8 0.1 0.75 9.7 0.0 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.6 AIO00463.1 - 0.0085 16.2 0.0 0.23 11.8 0.0 3.1 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_9 PF13371.6 AIO00463.1 - 0.019 15.1 0.1 0.17 12.0 0.5 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat Rad50_zn_hook PF04423.14 AIO00463.1 - 0.14 12.0 0.5 0.49 10.3 0.5 2.0 1 0 0 1 1 1 0 Rad50 zinc hook motif DUF2256 PF10013.9 AIO00463.1 - 0.35 11.0 6.0 4.3 7.5 0.5 2.5 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2256) DnaJ PF00226.31 AIO00464.1 - 1.2e-11 44.6 0.0 2.9e-11 43.3 0.0 1.7 1 0 0 1 1 1 1 DnaJ domain Plasmodium_Vir PF05795.11 AIO00464.1 - 0.0062 16.0 1.9 0.0085 15.6 1.7 1.3 1 1 0 1 1 1 1 Plasmodium vivax Vir protein BLUF PF04940.12 AIO00464.1 - 0.14 12.3 0.4 0.33 11.1 0.0 1.8 2 0 0 2 2 2 0 Sensors of blue-light using FAD Dzip-like_N PF13815.6 AIO00464.1 - 0.23 11.4 1.8 0.25 11.3 0.4 1.7 1 1 1 2 2 2 0 Iguana/Dzip1-like DAZ-interacting protein N-terminal HSP70 PF00012.20 AIO00465.1 - 1.2e-248 826.2 5.2 1.4e-248 826.0 5.2 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 AIO00465.1 - 1.4e-13 50.4 1.0 2.5e-12 46.3 0.3 2.6 2 1 0 2 2 2 1 MreB/Mbl protein DUF1690 PF07956.11 AIO00465.1 - 1.9 8.9 10.0 0.79 10.1 7.4 1.7 2 0 0 2 2 2 0 Protein of Unknown function (DUF1690) ApoO PF09769.9 AIO00465.1 - 3.3 7.7 5.6 0.88 9.5 1.1 2.2 2 0 0 2 2 2 0 Apolipoprotein O Cep57_CLD PF14073.6 AIO00465.1 - 4.1 7.4 13.1 0.15 12.1 7.3 1.5 2 0 0 2 2 2 0 Centrosome localisation domain of Cep57 Pyridoxal_deC PF00282.19 AIO00466.1 - 4.9e-91 305.2 0.0 5.9e-91 305.0 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Beta_elim_lyase PF01212.21 AIO00466.1 - 2.5e-05 23.7 0.1 3.1e-05 23.4 0.1 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase SepSecS PF05889.13 AIO00466.1 - 0.051 12.3 0.1 0.29 9.8 0.1 1.9 2 0 0 2 2 2 0 O-phosphoseryl-tRNA(Sec) selenium transferase, SepSecS DUF2749 PF10907.8 AIO00468.1 - 0.11 12.7 0.0 22 5.3 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2749) AAA PF00004.29 AIO00469.1 - 5.7e-47 159.4 0.0 4.1e-40 137.3 0.0 2.8 2 1 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 AIO00469.1 - 5.7e-13 48.5 0.8 2.9e-09 36.6 0.3 2.5 2 0 0 2 2 2 2 AAA+ lid domain AAA_16 PF13191.6 AIO00469.1 - 3.3e-06 27.6 4.3 0.2 12.0 0.0 4.2 2 2 0 3 3 3 1 AAA ATPase domain AAA_22 PF13401.6 AIO00469.1 - 4.3e-05 23.8 0.0 0.48 10.7 0.0 3.2 2 1 0 2 2 2 2 AAA domain RuvB_N PF05496.12 AIO00469.1 - 0.00023 20.9 0.0 0.00089 19.0 0.0 1.9 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 AIO00469.1 - 0.00041 20.4 0.0 0.041 13.9 0.0 3.5 3 1 0 3 3 3 1 AAA domain (dynein-related subfamily) Vps4_C PF09336.10 AIO00469.1 - 0.00069 19.6 0.0 0.0042 17.0 0.0 2.3 3 0 0 3 3 2 1 Vps4 C terminal oligomerisation domain AAA_33 PF13671.6 AIO00469.1 - 0.0042 17.3 0.1 0.7 10.0 0.0 3.0 3 0 0 3 3 3 1 AAA domain Zeta_toxin PF06414.12 AIO00469.1 - 0.0047 16.2 0.0 4.9 6.4 0.0 3.2 3 0 0 3 3 3 1 Zeta toxin TIP49 PF06068.13 AIO00469.1 - 0.0051 16.1 0.0 0.0098 15.1 0.0 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain RNA_helicase PF00910.22 AIO00469.1 - 0.0094 16.3 0.0 0.44 11.0 0.0 2.5 2 0 0 2 2 2 1 RNA helicase IstB_IS21 PF01695.17 AIO00469.1 - 0.0096 15.7 0.1 0.42 10.3 0.0 2.4 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_7 PF12775.7 AIO00469.1 - 0.01 15.4 0.1 0.69 9.4 0.0 2.7 2 1 0 2 2 2 1 P-loop containing dynein motor region AAA_25 PF13481.6 AIO00469.1 - 0.02 14.5 0.9 1.9 8.0 0.0 3.4 4 0 0 4 4 4 0 AAA domain ABC_tran PF00005.27 AIO00469.1 - 0.024 15.2 0.0 2.7 8.5 0.0 2.4 2 0 0 2 2 2 0 ABC transporter Rad17 PF03215.15 AIO00469.1 - 0.025 14.5 0.0 0.047 13.6 0.0 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_2 PF07724.14 AIO00469.1 - 0.025 14.7 0.0 0.079 13.1 0.0 1.8 2 0 0 2 2 1 0 AAA domain (Cdc48 subfamily) Mg_chelatase PF01078.21 AIO00469.1 - 0.03 13.7 0.0 0.074 12.4 0.0 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI ADSL_C PF10397.9 AIO00469.1 - 0.071 13.7 0.1 0.29 11.7 0.1 2.0 1 0 0 1 1 1 0 Adenylosuccinate lyase C-terminus AAA_28 PF13521.6 AIO00469.1 - 0.078 13.2 0.4 0.72 10.1 0.0 2.6 2 1 1 3 3 3 0 AAA domain HSP70 PF00012.20 AIO00470.1 - 5.9e-259 860.3 8.7 7e-259 860.1 8.7 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 AIO00470.1 - 1.5e-13 50.3 1.0 2.7e-12 46.2 0.3 2.6 2 1 0 2 2 2 1 MreB/Mbl protein TSNAXIP1_N PF15739.5 AIO00471.1 - 1.3e-05 25.5 6.9 0.0004 20.7 6.9 2.9 1 1 0 1 1 1 1 Translin-associated factor X-interacting N-terminus ERM PF00769.19 AIO00471.1 - 0.0034 17.2 0.9 0.0034 17.2 0.9 3.9 3 1 2 5 5 5 2 Ezrin/radixin/moesin family AAA_13 PF13166.6 AIO00471.1 - 0.015 14.0 5.3 0.024 13.3 5.3 1.2 1 0 0 1 1 1 0 AAA domain Uso1_p115_C PF04871.13 AIO00471.1 - 0.053 13.9 12.7 0.059 13.7 9.9 2.5 1 1 1 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region Rsd_AlgQ PF04353.13 AIO00471.1 - 0.061 13.3 1.4 0.3 11.0 0.7 2.3 2 0 0 2 2 2 0 Regulator of RNA polymerase sigma(70) subunit, Rsd/AlgQ HAUS6_N PF14661.6 AIO00471.1 - 0.9 9.1 4.6 2.8 7.5 4.6 1.9 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus DASH_Spc34 PF08657.10 AIO00471.1 - 1.4 8.6 4.9 3.2 7.5 4.9 1.5 1 0 0 1 1 1 0 DASH complex subunit Spc34 AATF-Che1 PF13339.6 AIO00471.1 - 2.9 8.5 6.7 8.4 7.1 3.6 2.9 2 0 0 2 2 2 0 Apoptosis antagonizing transcription factor Prefoldin PF02996.17 AIO00471.1 - 3.3 7.6 8.4 45 4.0 0.1 3.9 4 1 0 4 4 4 0 Prefoldin subunit DUF4407 PF14362.6 AIO00471.1 - 4.9 6.4 13.4 26 4.0 13.4 2.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) DUF4200 PF13863.6 AIO00471.1 - 9.7 6.6 12.5 0.42 11.0 1.9 3.6 2 1 1 3 3 3 0 Domain of unknown function (DUF4200) Cofilin_ADF PF00241.20 AIO00472.1 - 3.5e-10 39.7 0.0 1.8e-07 30.9 0.0 2.4 2 0 0 2 2 2 2 Cofilin/tropomyosin-type actin-binding protein GHBP PF12772.7 AIO00472.1 - 0.019 14.5 0.5 0.16 11.5 0.0 2.0 2 0 0 2 2 2 0 Growth hormone receptor binding RecT PF03837.14 AIO00472.1 - 0.11 11.9 0.0 0.29 10.6 0.0 1.6 2 0 0 2 2 2 0 RecT family Reticulon PF02453.17 AIO00473.1 - 6.2e-27 94.5 7.7 8.1e-27 94.1 7.7 1.2 1 0 0 1 1 1 1 Reticulon DUF3292 PF11696.8 AIO00473.1 - 0.001 17.6 1.2 0.0012 17.3 0.7 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF3292) DUF4806 PF16064.5 AIO00473.1 - 0.056 13.7 0.1 0.11 12.9 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4806) PrgI PF12666.7 AIO00473.1 - 0.16 12.7 4.6 0.46 11.2 0.3 2.3 2 0 0 2 2 2 0 PrgI family protein Leu_Phe_trans PF03588.14 AIO00474.1 - 0.00078 19.0 0.1 0.35 10.4 0.0 2.2 2 0 0 2 2 2 2 Leucyl/phenylalanyl-tRNA protein transferase FTHFS PF01268.19 AIO00475.1 - 1.4e-252 838.8 0.1 1.6e-252 838.7 0.1 1.0 1 0 0 1 1 1 1 Formate--tetrahydrofolate ligase CbiA PF01656.23 AIO00475.1 - 0.13 12.3 0.0 1.2 9.3 0.2 2.2 2 1 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain RRM_1 PF00076.22 AIO00476.1 - 3.1e-16 59.0 0.0 5.8e-16 58.1 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 AIO00476.1 - 0.00094 19.1 0.0 0.0015 18.4 0.0 1.3 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif DUF3138 PF11336.8 AIO00476.1 - 0.011 14.5 0.8 0.014 14.0 0.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) PHM7_cyt PF14703.6 AIO00476.1 - 0.15 12.3 0.5 4.2 7.6 0.0 2.2 2 0 0 2 2 2 0 Cytosolic domain of 10TM putative phosphate transporter MSP1a PF11670.8 AIO00478.1 - 0.088 12.1 0.0 0.13 11.6 0.0 1.2 1 0 0 1 1 1 0 Major surface protein 1a (MSP1a) AAA PF00004.29 AIO00479.1 - 1.4e-13 51.4 0.0 3.1e-13 50.3 0.0 1.6 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Rep_fac_C PF08542.11 AIO00479.1 - 1.8e-11 44.3 0.0 3.1e-11 43.5 0.0 1.4 1 0 0 1 1 1 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.6 AIO00479.1 - 3.8e-08 33.3 0.0 5.7e-06 26.2 0.0 2.3 2 0 0 2 2 2 1 DNA polymerase III, delta subunit AAA_22 PF13401.6 AIO00479.1 - 4.9e-05 23.6 0.0 0.00044 20.5 0.0 2.2 1 1 0 1 1 1 1 AAA domain AAA_11 PF13086.6 AIO00479.1 - 0.0002 21.3 0.0 0.00041 20.2 0.0 1.6 1 1 1 2 2 2 1 AAA domain AAA_16 PF13191.6 AIO00479.1 - 0.0033 17.8 0.8 0.028 14.8 0.0 2.6 2 2 1 3 3 3 1 AAA ATPase domain DUF2075 PF09848.9 AIO00479.1 - 0.0065 15.8 0.0 0.0093 15.2 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) RuvB_N PF05496.12 AIO00479.1 - 0.007 16.1 0.0 0.04 13.7 0.0 2.2 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_30 PF13604.6 AIO00479.1 - 0.0099 15.6 0.0 0.019 14.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.14 AIO00479.1 - 0.012 15.6 0.0 0.026 14.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_33 PF13671.6 AIO00479.1 - 0.032 14.4 0.0 0.061 13.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 AIO00479.1 - 0.065 13.5 0.0 0.13 12.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain Viral_helicase1 PF01443.18 AIO00479.1 - 0.079 12.7 0.0 0.16 11.7 0.0 1.6 1 1 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_24 PF13479.6 AIO00479.1 - 0.096 12.4 0.0 0.28 10.9 0.0 1.7 1 1 0 1 1 1 0 AAA domain DEAD PF00270.29 AIO00479.1 - 0.12 12.1 0.2 0.87 9.3 0.0 2.1 1 1 1 2 2 2 0 DEAD/DEAH box helicase AAA_assoc_2 PF16193.5 AIO00479.1 - 0.14 12.5 0.0 0.28 11.5 0.0 1.5 1 0 0 1 1 1 0 AAA C-terminal domain AAA_19 PF13245.6 AIO00479.1 - 0.17 12.2 0.1 0.4 11.0 0.1 1.7 1 1 0 1 1 1 0 AAA domain ubiquitin PF00240.23 AIO00482.1 - 6.3e-05 22.6 0.0 0.00011 21.9 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family TPR_12 PF13424.6 AIO00483.1 - 0.0055 17.0 4.7 0.035 14.4 1.7 3.0 2 1 1 3 3 3 2 Tetratricopeptide repeat SH3_2 PF07653.17 AIO00485.1 - 7.6e-07 28.7 0.0 1.3e-06 28.0 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.6 AIO00485.1 - 7.4e-06 25.7 0.0 1.1e-05 25.2 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 AIO00485.1 - 0.00013 21.5 0.0 0.00026 20.5 0.0 1.5 1 0 0 1 1 1 1 SH3 domain CortBP2 PF09727.9 AIO00485.1 - 0.0044 17.0 0.3 0.0063 16.4 0.3 1.2 1 0 0 1 1 1 1 Cortactin-binding protein-2 Tmemb_9 PF05434.11 AIO00485.1 - 0.21 11.5 0.8 0.4 10.6 0.8 1.4 1 0 0 1 1 1 0 TMEM9 GRAM PF02893.20 AIO00488.1 - 5.1e-11 42.5 0.1 1.1e-10 41.4 0.1 1.5 1 0 0 1 1 1 1 GRAM domain Smg8_Smg9 PF10220.9 AIO00488.1 - 0.17 10.2 1.0 0.26 9.6 1.0 1.2 1 0 0 1 1 1 0 Smg8_Smg9 SPA PF08616.10 AIO00489.1 - 5.1e-30 103.8 0.0 1e-29 102.8 0.0 1.6 1 0 0 1 1 1 1 Stabilization of polarity axis Avl9 PF09794.9 AIO00489.1 - 0.00041 19.1 0.0 0.034 12.8 0.0 2.2 1 1 1 2 2 2 2 Transport protein Avl9 DENN PF02141.21 AIO00489.1 - 0.0013 18.7 0.2 0.0044 17.0 0.0 2.1 1 1 1 2 2 2 1 DENN (AEX-3) domain DUF2347 PF09804.9 AIO00489.1 - 0.0091 15.6 0.0 0.014 15.0 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2347) HEAT_EZ PF13513.6 AIO00489.1 - 0.034 14.7 0.7 3.9 8.1 0.1 3.6 3 0 0 3 3 3 0 HEAT-like repeat TPR_1 PF00515.28 AIO00490.1 - 8.3e-25 85.5 7.7 8.7e-08 31.7 0.1 4.0 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.17 AIO00490.1 - 1.4e-17 62.3 13.9 2.2e-07 30.5 0.1 4.7 5 0 0 5 5 4 3 Tetratricopeptide repeat TPR_8 PF13181.6 AIO00490.1 - 2.1e-14 52.5 4.9 0.00014 21.8 0.0 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.6 AIO00490.1 - 1.6e-13 50.1 5.9 4.2e-06 26.3 0.6 3.6 1 1 2 3 3 3 3 TPR repeat TPR_17 PF13431.6 AIO00490.1 - 6.1e-09 35.6 2.8 0.0065 16.8 0.0 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.6 AIO00490.1 - 2.3e-08 33.5 1.0 0.048 13.7 0.0 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 AIO00490.1 - 4.7e-08 33.5 4.9 0.00032 21.3 0.0 3.0 3 1 0 4 4 2 2 Tetratricopeptide repeat TPR_12 PF13424.6 AIO00490.1 - 2e-07 31.2 4.4 6.6e-05 23.1 0.3 2.9 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.6 AIO00490.1 - 2e-07 31.2 0.1 0.023 15.5 0.0 4.0 1 1 2 3 3 3 2 Tetratricopeptide repeat SGT1 PF07093.11 AIO00490.1 - 6.3e-07 28.2 2.3 9.1e-07 27.7 2.3 1.2 1 0 0 1 1 1 1 SGT1 protein STI1 PF17830.1 AIO00490.1 - 4.4e-06 26.5 10.0 0.00094 19.1 0.1 3.4 4 0 0 4 4 2 2 STI1 domain TPR_19 PF14559.6 AIO00490.1 - 0.00015 22.2 3.6 0.14 12.7 0.1 2.9 3 0 0 3 3 2 2 Tetratricopeptide repeat TPR_9 PF13371.6 AIO00490.1 - 0.00052 20.1 0.1 0.01 16.0 0.1 2.2 1 1 1 2 2 2 2 Tetratricopeptide repeat TOM20_plant PF06552.12 AIO00490.1 - 0.0013 18.6 0.7 0.015 15.1 0.2 2.9 2 1 1 3 3 3 1 Plant specific mitochondrial import receptor subunit TOM20 TPR_10 PF13374.6 AIO00490.1 - 0.0036 17.1 6.9 2 8.4 0.0 3.9 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_6 PF13174.6 AIO00490.1 - 0.0073 16.9 2.8 0.69 10.7 0.1 3.9 4 0 0 4 4 4 1 Tetratricopeptide repeat ANAPC3 PF12895.7 AIO00490.1 - 0.012 15.8 3.9 0.17 12.1 0.6 2.7 1 1 1 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 MIT PF04212.18 AIO00490.1 - 0.037 14.1 6.5 1 9.5 0.5 3.7 3 0 0 3 3 3 0 MIT (microtubule interacting and transport) domain NRBF2_MIT PF17169.4 AIO00490.1 - 0.14 12.3 0.3 0.41 10.9 0.3 1.7 1 0 0 1 1 1 0 MIT domain of nuclear receptor-binding factor 2 Fis1_TPR_C PF14853.6 AIO00490.1 - 0.24 11.5 2.6 8.6 6.5 0.0 3.1 3 0 0 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat GerD PF17898.1 AIO00490.1 - 0.71 9.8 3.8 1.9 8.4 1.0 2.7 2 0 0 2 2 2 0 Spore germination GerD central core domain Smg4_UPF3 PF03467.15 AIO00490.1 - 0.85 9.6 4.9 0.6 10.1 1.8 2.3 3 0 0 3 3 3 0 Smg-4/UPF3 family Methyltransf_5 PF01795.19 AIO00491.1 - 0.0078 15.7 1.0 0.012 15.2 1.0 1.2 1 0 0 1 1 1 1 MraW methylase family DUF4168 PF13767.6 AIO00491.1 - 0.016 16.3 0.6 0.029 15.6 0.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4168) DSBA PF01323.20 AIO00491.1 - 0.079 12.7 0.8 0.12 12.1 0.8 1.2 1 0 0 1 1 1 0 DSBA-like thioredoxin domain VIT1 PF01988.19 AIO00491.1 - 0.31 10.9 1.5 0.53 10.1 1.5 1.3 1 0 0 1 1 1 0 VIT family TMA7 PF09072.10 AIO00492.1 - 5.9e-16 59.0 14.0 6.4e-16 58.9 14.0 1.0 1 0 0 1 1 1 1 Translation machinery associated TMA7 Sod_Fe_N PF00081.22 AIO00494.1 - 3e-06 27.6 0.2 4.5e-06 27.1 0.2 1.3 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain Sod_Fe_C PF02777.18 AIO00494.1 - 8.8e-05 22.6 0.0 0.0002 21.5 0.0 1.6 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain zf-CCCH PF00642.24 AIO00495.1 - 4e-06 26.6 2.1 4e-06 26.6 2.1 1.9 2 0 0 2 2 2 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 AIO00495.1 - 3.6e-05 23.7 4.5 7.3e-05 22.7 4.5 1.6 1 0 0 1 1 1 1 Zinc finger domain zf-CCCH_4 PF18044.1 AIO00495.1 - 6e-05 22.7 2.5 0.00012 21.8 2.5 1.5 1 0 0 1 1 1 1 CCCH-type zinc finger zf-CCCH_2 PF14608.6 AIO00495.1 - 0.12 12.9 1.9 0.27 11.8 1.9 1.6 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger DUF872 PF05915.12 AIO00496.1 - 2.1e-05 24.7 0.3 2.5e-05 24.4 0.3 1.3 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF872) Cpn60_TCP1 PF00118.24 AIO00499.1 - 5.1e-67 226.6 8.4 1.3e-66 225.3 8.4 1.5 1 1 0 1 1 1 1 TCP-1/cpn60 chaperonin family TcpQ PF10671.9 AIO00499.1 - 0.15 12.2 1.9 3.5 7.8 0.0 3.3 3 1 0 3 3 3 0 Toxin co-regulated pilus biosynthesis protein Q RabGAP-TBC PF00566.18 AIO00501.1 - 5.4e-34 117.7 0.3 3.9e-33 114.9 0.3 1.9 1 1 0 1 1 1 1 Rab-GTPase-TBC domain DUF4597 PF15366.6 AIO00505.1 - 0.00087 19.0 0.4 0.0037 17.0 0.4 2.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4597) GAT PF03127.14 AIO00505.1 - 0.056 13.8 0.0 0.19 12.1 0.0 2.0 1 0 0 1 1 1 0 GAT domain EMP24_GP25L PF01105.24 AIO00505.1 - 0.19 11.6 0.3 0.33 10.9 0.3 1.3 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD DUF737 PF05300.11 AIO00505.1 - 2.3 8.5 8.8 0.54 10.6 0.2 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF737) PPR_2 PF13041.6 AIO00506.1 - 0.0006 20.0 0.0 19 5.6 0.0 4.6 5 0 0 5 5 5 1 PPR repeat family PPR PF01535.20 AIO00506.1 - 0.0023 18.1 1.5 27 5.3 0.0 5.3 7 0 0 7 7 7 1 PPR repeat TPR_7 PF13176.6 AIO00506.1 - 0.0043 17.0 2.6 59 4.0 0.0 5.6 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_19 PF14559.6 AIO00506.1 - 0.8 10.3 5.3 17 6.0 0.0 4.2 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_14 PF13428.6 AIO00506.1 - 0.95 10.5 14.8 37 5.5 0.1 6.3 5 2 2 7 7 7 0 Tetratricopeptide repeat DUF4911 PF16256.5 AIO00507.1 - 0.014 15.3 0.1 0.03 14.3 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4911) Aldedh PF00171.22 AIO00508.1 - 5.4e-118 394.4 0.0 6.9e-118 394.1 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.11 AIO00508.1 - 0.0077 15.7 0.0 0.026 14.0 0.0 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF1487) Med27 PF11571.8 AIO00508.1 - 0.095 13.1 0.0 0.2 12.0 0.0 1.5 1 0 0 1 1 1 0 Mediator complex subunit 27 Pkinase PF00069.25 AIO00509.1 - 8.5e-53 179.4 0.0 1.4e-52 178.7 0.0 1.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 AIO00509.1 - 1.4e-17 63.8 0.0 1.8e-17 63.5 0.0 1.3 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 AIO00509.1 - 4.6e-07 29.4 0.1 8.4e-07 28.6 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 AIO00509.1 - 0.0012 18.8 0.2 0.0018 18.2 0.2 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.6 AIO00509.1 - 0.0027 17.1 0.0 0.0074 15.6 0.0 1.7 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 AIO00509.1 - 0.023 13.5 0.1 0.04 12.7 0.1 1.3 1 0 0 1 1 1 0 Fungal protein kinase DUF572 PF04502.13 AIO00510.1 - 3.1 7.3 12.2 0.3 10.7 1.5 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF572) zf-CHCC PF10276.9 AIO00513.1 - 0.00041 20.3 2.9 0.00041 20.3 2.9 1.9 2 0 0 2 2 2 1 Zinc-finger domain Gp_dh_C PF02800.20 AIO00514.1 - 2.6e-63 212.3 0.0 4e-63 211.7 0.0 1.3 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.24 AIO00514.1 - 1.9e-29 102.0 0.0 3.8e-29 101.0 0.0 1.5 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain DapB_N PF01113.20 AIO00514.1 - 0.0054 16.9 1.3 0.011 15.8 0.3 2.2 2 1 0 2 2 2 1 Dihydrodipicolinate reductase, N-terminus GFO_IDH_MocA PF01408.22 AIO00514.1 - 0.096 13.5 0.0 0.17 12.7 0.0 1.4 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold DUF2817 PF10994.8 AIO00515.1 - 2.1e-108 362.7 0.4 2.5e-108 362.5 0.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2817) AstE_AspA PF04952.14 AIO00515.1 - 1.5e-05 24.3 0.0 3.2e-05 23.1 0.0 1.5 1 0 0 1 1 1 1 Succinylglutamate desuccinylase / Aspartoacylase family TPR_1 PF00515.28 AIO00517.1 - 1.6e-97 315.7 34.5 7.3e-08 31.9 0.7 15.0 15 0 0 15 15 15 14 Tetratricopeptide repeat TPR_2 PF07719.17 AIO00517.1 - 5e-80 257.3 47.7 1.1e-06 28.3 0.7 15.6 15 0 0 15 15 15 14 Tetratricopeptide repeat TPR_11 PF13414.6 AIO00517.1 - 3.4e-58 193.1 33.9 6.7e-09 35.3 1.0 13.8 5 2 8 13 13 13 11 TPR repeat TPR_8 PF13181.6 AIO00517.1 - 5.5e-54 175.9 27.0 4.9e-05 23.2 0.7 13.4 14 0 0 14 14 14 11 Tetratricopeptide repeat TPR_16 PF13432.6 AIO00517.1 - 7.7e-50 167.3 47.9 2.3e-07 31.4 0.3 9.7 7 2 2 9 9 9 9 Tetratricopeptide repeat TPR_17 PF13431.6 AIO00517.1 - 2.5e-40 134.0 25.6 1.2e-05 25.3 0.1 13.0 13 0 0 13 13 13 7 Tetratricopeptide repeat TPR_9 PF13371.6 AIO00517.1 - 3.3e-39 132.9 36.0 2.1e-05 24.6 0.1 11.9 4 3 6 11 11 11 10 Tetratricopeptide repeat TPR_12 PF13424.6 AIO00517.1 - 3.2e-32 110.6 49.6 2.6e-06 27.6 1.5 10.1 8 4 3 11 11 11 8 Tetratricopeptide repeat TPR_7 PF13176.6 AIO00517.1 - 6.2e-28 94.7 31.1 0.0025 17.7 0.2 13.5 13 1 1 14 14 14 7 Tetratricopeptide repeat TPR_14 PF13428.6 AIO00517.1 - 1.1e-20 72.5 36.6 0.0036 18.0 0.0 13.5 4 2 11 15 15 15 4 Tetratricopeptide repeat TPR_6 PF13174.6 AIO00517.1 - 2.3e-19 68.7 44.7 0.21 12.3 0.0 13.7 15 0 0 15 15 14 6 Tetratricopeptide repeat TPR_19 PF14559.6 AIO00517.1 - 3.1e-16 59.6 27.9 0.0028 18.1 1.8 9.8 5 3 4 10 10 10 5 Tetratricopeptide repeat SHNi-TPR PF10516.9 AIO00517.1 - 4.8e-09 35.5 14.0 1.5 8.4 0.0 10.0 10 0 0 10 10 10 2 SHNi-TPR TPR_10 PF13374.6 AIO00517.1 - 8.2e-09 35.1 41.3 0.093 12.6 0.1 11.4 13 0 0 13 13 12 4 Tetratricopeptide repeat TPR_15 PF13429.6 AIO00517.1 - 0.00014 21.2 15.0 0.37 10.0 0.2 6.5 3 1 1 6 6 6 1 Tetratricopeptide repeat ANAPC3 PF12895.7 AIO00517.1 - 0.00055 20.1 31.8 0.33 11.2 1.4 7.4 6 2 2 8 8 7 2 Anaphase-promoting complex, cyclosome, subunit 3 Coatomer_E PF04733.14 AIO00517.1 - 0.003 17.0 0.4 6.4 6.1 0.0 3.9 4 0 0 4 4 4 1 Coatomer epsilon subunit TPR_20 PF14561.6 AIO00517.1 - 0.0037 17.6 11.3 10 6.5 0.0 6.3 6 1 1 7 7 7 0 Tetratricopeptide repeat BTAD PF03704.17 AIO00517.1 - 0.017 15.6 25.1 0.9 10.0 0.6 6.5 5 3 2 8 8 7 0 Bacterial transcriptional activator domain DUF3856 PF12968.7 AIO00517.1 - 0.031 14.4 11.2 24 5.0 0.1 7.3 4 2 2 6 6 6 0 Domain of Unknown Function (DUF3856) PA28_beta PF02252.18 AIO00517.1 - 0.039 13.6 5.7 3.5 7.3 0.0 4.7 4 1 1 5 5 5 0 Proteasome activator pa28 beta subunit NARP1 PF12569.8 AIO00517.1 - 0.084 11.8 11.7 0.61 8.9 0.1 4.5 2 1 3 5 5 5 0 NMDA receptor-regulated protein 1 T2SSF PF00482.23 AIO00517.1 - 0.099 12.6 0.1 0.56 10.2 0.0 2.2 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein F MIT PF04212.18 AIO00517.1 - 0.1 12.7 0.3 0.1 12.7 0.3 9.5 10 1 1 11 11 11 0 MIT (microtubule interacting and transport) domain NdhN PF11909.8 AIO00517.1 - 0.14 11.8 0.0 0.27 10.9 0.0 1.4 1 0 0 1 1 1 0 NADH-quinone oxidoreductase cyanobacterial subunit N Fis1_TPR_C PF14853.6 AIO00517.1 - 2.2 8.4 28.0 3.1 7.9 0.1 7.6 7 2 2 9 9 7 0 Fis1 C-terminal tetratricopeptide repeat LSM PF01423.22 AIO00518.1 - 6.6e-08 32.1 0.3 1.1e-07 31.4 0.3 1.4 1 1 0 1 1 1 1 LSM domain KH_8 PF17903.1 AIO00519.1 - 8.4e-26 89.9 0.0 1.8e-25 88.8 0.0 1.5 1 0 0 1 1 1 1 Krr1 KH1 domain DUF21 PF01595.20 AIO00521.1 - 3.4e-26 92.0 5.3 7.1e-26 91.0 5.3 1.5 1 0 0 1 1 1 1 Cyclin M transmembrane N-terminal domain CBS PF00571.28 AIO00521.1 - 3.6e-06 27.3 0.1 0.0033 17.8 0.0 2.8 3 0 0 3 3 3 2 CBS domain DUF5325 PF17259.2 AIO00521.1 - 4.6 7.2 8.3 0.13 12.2 0.5 2.3 2 1 0 2 2 2 0 Family of unknown function (DUF5325) eIF-3_zeta PF05091.12 AIO00522.1 - 3.6e-93 313.3 0.0 4.2e-93 313.1 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Pkinase PF00069.25 AIO00523.1 - 1.7e-65 221.0 0.0 2.4e-65 220.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 AIO00523.1 - 2.6e-44 151.5 0.0 3.9e-44 150.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 AIO00523.1 - 0.0015 17.4 0.0 0.0025 16.6 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 AIO00523.1 - 0.0041 16.5 0.0 0.0078 15.6 0.0 1.4 1 0 0 1 1 1 1 Kinase-like G8 PF10162.9 AIO00523.1 - 0.03 14.4 0.4 3.5 7.7 0.0 2.9 2 0 0 2 2 2 0 G8 domain Seadorna_VP7 PF07387.11 AIO00523.1 - 0.066 12.3 0.0 0.48 9.4 0.0 2.0 2 0 0 2 2 2 0 Seadornavirus VP7 Kinesin PF00225.23 AIO00524.1 - 9.8e-82 274.5 0.0 9.8e-82 274.5 0.0 2.5 3 0 0 3 3 3 1 Kinesin motor domain Microtub_bd PF16796.5 AIO00524.1 - 2.5e-19 69.7 0.0 1.4e-18 67.3 0.0 2.3 2 0 0 2 2 2 1 Microtubule binding PKcGMP_CC PF16808.5 AIO00524.1 - 0.0059 16.4 1.0 0.0059 16.4 1.0 6.9 6 0 0 6 6 6 2 Coiled-coil N-terminus of cGMP-dependent protein kinase tRNA_m1G_MT PF01746.21 AIO00525.1 - 2.3e-18 66.6 0.1 4.9e-18 65.5 0.0 1.5 2 0 0 2 2 2 1 tRNA (Guanine-1)-methyltransferase F_actin_bund_C PF18060.1 AIO00525.1 - 0.081 13.1 9.6 0.17 12.1 9.6 1.4 1 0 0 1 1 1 0 F actin bundling C terminal GHMP_kinases_N PF00288.26 AIO00526.1 - 5.8e-09 36.0 0.9 5.8e-09 36.0 0.9 2.1 3 0 0 3 3 3 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 AIO00526.1 - 7.9e-07 29.4 0.1 1.8e-06 28.2 0.1 1.6 1 0 0 1 1 1 1 GHMP kinases C terminal PPR_3 PF13812.6 AIO00528.1 - 0.013 15.6 0.1 3.4 7.8 0.0 3.7 6 0 0 6 6 6 0 Pentatricopeptide repeat domain PsbW PF07123.12 AIO00528.1 - 0.11 12.4 1.5 8.2 6.5 0.0 2.7 2 0 0 2 2 2 0 Photosystem II reaction centre W protein (PsbW) SAM_decarbox PF01536.16 AIO00529.1 - 2.8e-89 299.6 0.0 3.3e-89 299.4 0.0 1.0 1 0 0 1 1 1 1 Adenosylmethionine decarboxylase SAM_decarbox PF01536.16 AIO00530.1 - 1.3e-13 50.7 0.1 3.7e-08 32.8 0.0 2.1 2 0 0 2 2 2 2 Adenosylmethionine decarboxylase tRNA-synt_1 PF00133.22 AIO00531.1 - 1.4e-192 641.2 0.0 1.5e-191 637.8 0.0 1.9 1 1 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 AIO00531.1 - 3.1e-34 118.1 0.0 5.3e-34 117.4 0.0 1.4 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA Val_tRNA-synt_C PF10458.9 AIO00531.1 - 4.3e-15 55.7 1.5 9.5e-15 54.6 1.5 1.6 1 0 0 1 1 1 1 Valyl tRNA synthetase tRNA binding arm tRNA-synt_1g PF09334.11 AIO00531.1 - 7.4e-14 51.3 0.2 3.7e-07 29.2 0.0 3.8 3 1 0 3 3 3 3 tRNA synthetases class I (M) tRNA-synt_1_2 PF13603.6 AIO00531.1 - 8.8e-08 31.9 0.0 0.00046 19.7 0.0 2.6 1 1 1 2 2 2 2 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1e PF01406.19 AIO00531.1 - 0.0083 15.5 0.2 1.2 8.4 0.1 3.2 4 0 0 4 4 4 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1b PF00579.25 AIO00531.1 - 0.053 12.8 0.1 0.15 11.3 0.0 1.7 2 0 0 2 2 2 0 tRNA synthetases class I (W and Y) TRAP_beta PF05753.14 AIO00533.1 - 2.3e-10 40.2 2.2 2.1e-09 37.0 2.2 2.4 1 1 0 1 1 1 1 Translocon-associated protein beta (TRAPB) DUF11 PF01345.18 AIO00533.1 - 2.9e-08 33.9 0.9 1.1e-07 32.0 0.9 2.0 1 1 0 1 1 1 1 Domain of unknown function DUF11 CARDB PF07705.11 AIO00533.1 - 1.9e-05 24.9 0.5 2.9e-05 24.3 0.5 1.3 1 0 0 1 1 1 1 CARDB NPCBM_assoc PF10633.9 AIO00533.1 - 0.011 15.9 0.1 0.049 13.9 0.1 2.0 1 1 0 1 1 1 0 NPCBM-associated, NEW3 domain of alpha-galactosidase DUF5006 PF16397.5 AIO00533.1 - 0.022 14.0 0.3 0.033 13.4 0.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5006) TPH PF13868.6 AIO00535.1 - 2.1e-41 141.6 131.1 2.1e-41 141.6 131.1 1.8 2 0 0 2 2 2 1 Trichohyalin-plectin-homology domain RRM_1 PF00076.22 AIO00536.1 - 4.3e-08 32.9 0.0 6.3e-08 32.3 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 AIO00536.1 - 0.031 13.8 0.0 0.059 13.0 0.0 1.5 1 1 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) HMG-CoA_red PF00368.18 AIO00537.1 - 3.2e-133 444.3 4.8 3.7e-133 444.1 4.8 1.0 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A reductase Ribosomal_S26e PF01283.19 AIO00538.1 - 8.6e-36 122.7 3.6 9.1e-36 122.6 3.6 1.0 1 0 0 1 1 1 1 Ribosomal protein S26e Lebercilin PF15619.6 AIO00539.1 - 0.00044 20.0 12.1 0.00044 20.0 12.1 3.0 2 1 1 3 3 3 1 Ciliary protein causing Leber congenital amaurosis disease DUF4686 PF15742.5 AIO00539.1 - 0.019 14.1 35.2 0.24 10.5 5.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4686) DUF2274 PF10038.9 AIO00539.1 - 0.063 13.7 0.3 0.24 11.9 0.3 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2274) FKBP_C PF00254.28 AIO00539.1 - 0.15 12.4 0.0 0.43 10.9 0.0 1.8 1 0 0 1 1 1 0 FKBP-type peptidyl-prolyl cis-trans isomerase DUF4250 PF14056.6 AIO00539.1 - 0.95 9.5 3.8 0.97 9.4 0.6 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF4250) SepRS_C PF18006.1 AIO00540.1 - 0.24 11.5 0.4 2 8.6 0.1 2.4 2 0 0 2 2 2 0 O-phosphoseryl-tRNA synthetase C-terminal domain tRNA-synt_1c PF00749.21 AIO00543.1 - 1.2e-104 349.7 0.1 1.7e-104 349.1 0.1 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.18 AIO00543.1 - 1e-34 119.9 0.1 2.4e-34 118.7 0.1 1.6 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain HA2 PF04408.23 AIO00544.1 - 3e-13 50.0 0.0 3e-13 50.0 0.0 2.8 2 1 0 2 2 1 1 Helicase associated domain (HA2) Helicase_C PF00271.31 AIO00544.1 - 9.2e-10 38.9 0.0 5.1e-09 36.5 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 AIO00544.1 - 4.5e-09 36.3 0.0 6.9e-08 32.5 0.0 2.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase OB_NTP_bind PF07717.16 AIO00544.1 - 5.1e-07 30.0 0.0 1e-06 29.0 0.0 1.5 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold AAA_22 PF13401.6 AIO00544.1 - 1.4e-06 28.7 2.4 1e-05 25.8 0.0 3.0 3 0 0 3 3 3 1 AAA domain ResIII PF04851.15 AIO00544.1 - 9.6e-05 22.5 0.1 0.00035 20.6 0.0 2.1 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 AIO00544.1 - 0.00021 21.7 0.0 0.00094 19.5 0.0 2.1 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.6 AIO00544.1 - 0.034 13.9 0.0 0.085 12.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain ATPase PF06745.13 AIO00544.1 - 0.15 11.4 0.0 0.15 11.4 0.0 2.3 3 0 0 3 3 3 0 KaiC AAA_16 PF13191.6 AIO00544.1 - 0.39 11.1 0.0 0.39 11.1 0.0 3.3 2 1 1 3 3 3 0 AAA ATPase domain AAA_23 PF13476.6 AIO00544.1 - 1.4 9.3 0.0 1.4 9.3 0.0 2.7 2 0 0 2 2 1 0 AAA domain DUF4890 PF16231.5 AIO00544.1 - 3.5 8.2 18.6 9.2 6.8 18.6 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4890) AAA_11 PF13086.6 AIO00544.1 - 5.4 6.7 0.0 5.4 6.7 0.0 3.1 3 0 0 3 3 3 0 AAA domain Ank_2 PF12796.7 AIO00545.1 - 2.3e-35 121.0 7.1 4e-11 43.4 0.0 4.2 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 AIO00545.1 - 1.5e-30 105.1 7.1 9.2e-09 35.7 0.0 6.5 2 2 4 6 6 6 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 AIO00545.1 - 1.1e-26 89.9 4.6 0.0016 18.7 0.0 7.6 7 0 0 7 7 7 7 Ankyrin repeat Ank PF00023.30 AIO00545.1 - 1.7e-23 82.0 6.5 0.00038 20.8 0.0 7.3 7 0 0 7 7 7 6 Ankyrin repeat Ank_5 PF13857.6 AIO00545.1 - 4.2e-23 81.1 9.4 5.5e-07 29.8 0.3 6.3 4 1 2 6 6 6 4 Ankyrin repeats (many copies) Preseq_ALAS PF09029.10 AIO00545.1 - 0.16 12.5 1.4 1.5 9.3 0.1 2.6 2 0 0 2 2 2 0 5-aminolevulinate synthase presequence Sensor PF13796.6 AIO00546.1 - 0.0093 16.0 0.6 0.013 15.5 0.6 1.2 1 0 0 1 1 1 1 Putative sensor Metallophos PF00149.28 AIO00547.1 - 2.3e-09 38.0 0.0 3.7e-09 37.4 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase XPC-binding PF09280.11 AIO00549.1 - 1e-15 57.2 0.1 2e-15 56.2 0.1 1.5 1 0 0 1 1 1 1 XPC-binding domain ubiquitin PF00240.23 AIO00549.1 - 7.5e-13 48.0 0.0 1.4e-12 47.2 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family UBA PF00627.31 AIO00549.1 - 9.5e-10 38.2 6.3 2e-06 27.6 1.2 2.5 2 0 0 2 2 2 2 UBA/TS-N domain Rad60-SLD PF11976.8 AIO00549.1 - 2.6e-06 27.2 0.2 6.3e-06 25.9 0.2 1.7 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like UBA_3 PF09288.10 AIO00549.1 - 0.0055 16.5 0.0 0.03 14.1 0.0 2.1 2 0 0 2 2 2 1 Fungal ubiquitin-associated domain MCM_N PF14551.6 AIO00549.1 - 0.0083 16.7 0.0 0.018 15.6 0.0 1.5 1 0 0 1 1 1 1 MCM N-terminal domain MORN PF02493.20 AIO00550.1 - 6.3e-93 299.4 108.5 3e-10 39.4 2.5 15.2 15 0 0 15 15 15 15 MORN repeat Peptidase_S55 PF05580.12 AIO00550.1 - 0.03 14.3 9.1 1.4 8.9 0.2 5.2 3 2 2 5 5 5 0 SpoIVB peptidase S55 DUF2158 PF09926.9 AIO00550.1 - 6.2 6.6 8.1 7.4 6.4 0.0 5.0 4 1 4 8 8 8 0 Uncharacterized small protein (DUF2158) BAR PF03114.18 AIO00551.1 - 9.6e-05 22.1 3.5 0.00022 21.0 3.4 1.5 1 1 0 1 1 1 1 BAR domain Vsr PF03852.15 AIO00551.1 - 0.12 12.3 0.0 0.24 11.3 0.0 1.4 1 0 0 1 1 1 0 DNA mismatch endonuclease Vsr Ribosomal_L6 PF00347.23 AIO00553.1 - 3.2e-25 88.6 2.5 4.6e-14 52.8 0.4 2.1 2 0 0 2 2 2 2 Ribosomal protein L6 Glyco_hydro_65C PF03633.15 AIO00553.1 - 0.06 13.3 0.2 5.8 6.9 0.1 3.0 3 1 0 3 3 3 0 Glycosyl hydrolase family 65, C-terminal domain EF-hand_7 PF13499.6 AIO00555.1 - 2.7e-39 133.4 15.3 4.9e-08 33.3 0.0 6.2 6 1 0 6 6 6 5 EF-hand domain pair EF-hand_1 PF00036.32 AIO00555.1 - 3.3e-36 120.1 14.7 0.00012 21.4 0.0 10.8 11 0 0 11 11 11 7 EF hand EF-hand_6 PF13405.6 AIO00555.1 - 1.8e-33 111.5 12.1 0.00027 20.6 0.0 10.4 10 0 0 10 10 10 7 EF-hand domain EF-hand_5 PF13202.6 AIO00555.1 - 4.2e-32 108.2 6.8 6.1e-05 22.3 0.0 9.3 9 0 0 9 9 9 6 EF hand EF-hand_8 PF13833.6 AIO00555.1 - 1.7e-19 69.4 16.5 0.0015 18.3 0.0 9.9 8 3 1 9 9 9 6 EF-hand domain pair SPARC_Ca_bdg PF10591.9 AIO00555.1 - 1.7e-10 41.2 0.3 0.2 12.0 0.0 5.7 4 2 1 5 5 5 2 Secreted protein acidic and rich in cysteine Ca binding region Caleosin PF05042.13 AIO00555.1 - 0.012 15.5 0.7 13 5.7 0.0 4.3 4 0 0 4 4 4 0 Caleosin related protein EF-hand_13 PF17958.1 AIO00555.1 - 0.016 15.0 0.0 17 5.3 0.1 3.8 2 1 0 2 2 2 0 EF-hand domain SHOCT PF09851.9 AIO00555.1 - 0.031 14.0 0.8 14 5.6 0.0 3.8 3 0 0 3 3 3 0 Short C-terminal domain DUF3349 PF11829.8 AIO00555.1 - 0.091 13.6 0.4 12 6.7 0.0 3.9 4 0 0 4 4 4 0 Protein of unknown function (DUF3349) EF-hand_10 PF14788.6 AIO00555.1 - 0.13 12.2 0.0 13 5.7 0.0 3.9 4 0 0 4 4 4 0 EF hand PGK PF00162.19 AIO00557.1 - 1.5e-137 458.6 0.1 1.8e-137 458.3 0.1 1.1 1 0 0 1 1 1 1 Phosphoglycerate kinase PAS PF00989.25 AIO00557.1 - 5.6e-07 29.6 0.0 2e-06 27.8 0.0 1.9 2 0 0 2 2 2 1 PAS fold PAS_4 PF08448.10 AIO00557.1 - 2.9e-05 24.3 0.0 8.5e-05 22.8 0.0 1.8 2 0 0 2 2 2 1 PAS fold PAS_8 PF13188.7 AIO00557.1 - 0.00054 19.9 0.0 0.0019 18.2 0.0 1.9 1 0 0 1 1 1 1 PAS domain PAS_9 PF13426.7 AIO00557.1 - 0.0018 18.5 0.0 0.0089 16.3 0.0 2.2 2 0 0 2 2 2 1 PAS domain bPH_1 PF08000.11 AIO00557.1 - 0.12 12.5 0.2 0.23 11.5 0.2 1.5 1 0 0 1 1 1 0 Bacterial PH domain CAS_CSE1 PF03378.15 AIO00558.1 - 3e-64 217.2 0.0 5.9e-64 216.2 0.0 1.5 1 0 0 1 1 1 1 CAS/CSE protein, C-terminus Cse1 PF08506.10 AIO00558.1 - 1.2e-45 156.0 0.0 1.6e-45 155.5 0.0 1.2 1 0 0 1 1 1 1 Cse1 IBN_N PF03810.19 AIO00558.1 - 0.00029 20.7 0.0 0.0048 16.8 0.0 2.7 2 0 0 2 2 2 1 Importin-beta N-terminal domain Xpo1 PF08389.12 AIO00558.1 - 0.0065 16.5 0.7 1.7 8.7 0.2 3.6 2 1 0 2 2 2 1 Exportin 1-like protein MCM_N PF14551.6 AIO00558.1 - 0.14 12.8 0.2 3.9 8.1 0.0 3.0 3 0 0 3 3 3 0 MCM N-terminal domain WD40 PF00400.32 AIO00560.1 - 3.1e-07 31.0 10.3 0.36 11.8 0.5 5.1 5 0 0 5 5 5 4 WD domain, G-beta repeat Dynein_heavy PF03028.15 AIO00560.1 - 2.1e-06 27.8 0.0 5.6e-06 26.4 0.0 1.7 1 0 0 1 1 1 1 Dynein heavy chain region D6 P-loop domain Tcp11 PF05794.13 AIO00561.1 - 8.9e-29 100.8 2.5 1.6e-28 100.0 2.5 1.4 1 0 0 1 1 1 1 T-complex protein 11 MKT1_C PF12246.8 AIO00562.1 - 6.8e-16 58.2 0.0 1e-15 57.7 0.0 1.3 1 0 0 1 1 1 1 Temperature dependent protein affecting M2 dsRNA replication MKT1_N PF12247.8 AIO00562.1 - 5.4e-08 33.1 0.0 1.6e-07 31.6 0.0 1.8 1 0 0 1 1 1 1 Temperature dependent protein affecting M2 dsRNA replication DNA_ligase_A_M PF01068.21 AIO00563.1 - 3.4e-54 183.6 0.0 5.5e-54 182.9 0.0 1.3 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.14 AIO00563.1 - 4e-32 111.9 0.0 8.9e-32 110.8 0.0 1.6 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_C PF04679.15 AIO00563.1 - 6.1e-24 84.5 0.2 4.6e-23 81.7 0.0 2.3 2 0 0 2 2 2 1 ATP dependent DNA ligase C terminal region RNA_ligase PF09414.10 AIO00563.1 - 3.1e-05 24.3 0.0 5.8e-05 23.5 0.0 1.5 1 0 0 1 1 1 1 RNA ligase DNA_ligase_OB_2 PF14743.6 AIO00563.1 - 0.35 10.9 3.1 4.7 7.3 0.0 3.2 3 0 0 3 3 3 0 DNA ligase OB-like domain TPR_16 PF13432.6 AIO00565.1 - 9.2e-09 35.8 2.3 0.00051 20.6 0.1 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 AIO00565.1 - 1.1e-08 35.2 4.2 0.15 12.9 0.1 4.6 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_17 PF13431.6 AIO00565.1 - 3.1e-06 27.2 0.9 5.6 7.6 0.0 4.4 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_9 PF13371.6 AIO00565.1 - 9.6e-06 25.7 6.1 0.0031 17.6 0.2 3.9 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 AIO00565.1 - 1.2e-05 25.0 4.2 0.012 15.7 0.0 4.4 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_19 PF14559.6 AIO00565.1 - 5.7e-05 23.6 3.5 0.0024 18.3 0.1 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.28 AIO00565.1 - 0.0001 22.0 0.2 11 6.1 0.1 4.1 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_11 PF13414.6 AIO00565.1 - 0.00034 20.2 0.6 6.9 6.5 0.0 4.2 4 0 0 4 4 4 1 TPR repeat TTC5_OB PF16669.5 AIO00565.1 - 0.0018 18.0 0.2 0.019 14.6 0.2 2.1 1 1 0 1 1 1 1 Tetratricopeptide repeat protein 5 OB fold domain TPR_15 PF13429.6 AIO00565.1 - 0.04 13.1 0.4 0.18 11.0 0.1 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat ANAPC3 PF12895.7 AIO00565.1 - 0.042 14.1 0.5 0.12 12.6 0.1 1.9 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.6 AIO00565.1 - 0.042 14.1 0.2 5.7 7.4 0.0 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat ChAPs PF09295.10 AIO00565.1 - 0.086 11.8 0.1 0.11 11.4 0.1 1.1 1 0 0 1 1 1 0 ChAPs (Chs5p-Arf1p-binding proteins) Yippee-Mis18 PF03226.14 AIO00566.1 - 4.1e-11 43.0 0.2 5.4e-11 42.6 0.2 1.1 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly RIG-I_C-RD PF11648.8 AIO00566.1 - 0.0008 19.6 0.2 0.0011 19.2 0.2 1.2 1 0 0 1 1 1 1 C-terminal domain of RIG-I C1_4 PF07975.12 AIO00566.1 - 0.29 11.4 4.3 1.4 9.2 0.1 2.4 2 1 0 2 2 2 0 TFIIH C1-like domain Pkinase PF00069.25 AIO00567.1 - 5e-22 78.5 0.0 6.3e-22 78.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 AIO00567.1 - 1.8e-12 47.1 0.0 2.1e-12 46.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 AIO00567.1 - 1.2e-09 37.5 0.0 1.6e-09 37.1 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 AIO00567.1 - 0.12 12.3 0.0 0.23 11.3 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family DUF4831 PF16115.5 AIO00568.1 - 0.13 11.3 0.2 0.18 10.8 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4831) Pneumo_att_G PF05539.11 AIO00568.1 - 2.4 7.7 6.6 3.2 7.2 6.6 1.2 1 0 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G zf-MIZ PF02891.20 AIO00569.1 - 1.7e-18 66.1 5.6 3e-18 65.3 5.6 1.4 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger zf-Nse PF11789.8 AIO00569.1 - 2.4e-07 30.5 1.3 4.6e-07 29.6 1.3 1.5 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit NUDE_C PF04880.13 AIO00569.1 - 0.029 14.8 0.4 0.061 13.8 0.4 1.5 1 0 0 1 1 1 0 NUDE protein, C-terminal conserved region CYLD_phos_site PF16607.5 AIO00569.1 - 0.1 12.4 0.1 0.2 11.5 0.1 1.4 1 0 0 1 1 1 0 Phosphorylation region of CYLD, unstructured zf-C3HC4_4 PF15227.6 AIO00569.1 - 0.63 10.2 5.8 1.2 9.4 5.8 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.6 AIO00569.1 - 2.5 8.0 7.3 5.1 7.0 7.3 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) S-AdoMet_synt_C PF02773.16 AIO00570.1 - 7.8e-65 217.0 0.0 1.5e-64 216.1 0.0 1.5 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, C-terminal domain S-AdoMet_synt_M PF02772.16 AIO00570.1 - 7.8e-42 142.3 0.0 7.1e-41 139.2 0.0 2.1 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, central domain S-AdoMet_synt_N PF00438.20 AIO00570.1 - 6.8e-41 139.0 0.3 1.5e-40 137.9 0.3 1.6 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, N-terminal domain Strep_pep PF14404.6 AIO00570.1 - 0.022 15.0 0.0 0.09 13.1 0.0 2.0 2 0 0 2 2 2 0 Ribosomally synthesized peptide in Streptomyces species AdoMet_Synthase PF01941.19 AIO00570.1 - 0.17 10.6 0.6 1.4 7.6 0.1 2.2 1 1 1 2 2 2 0 S-adenosylmethionine synthetase (AdoMet synthetase) Rhodanese PF00581.20 AIO00571.1 - 9.9e-06 26.0 0.0 1.7e-05 25.2 0.0 1.3 1 0 0 1 1 1 1 Rhodanese-like domain RF-1 PF00472.20 AIO00572.1 - 7.5e-08 32.3 0.3 2.4e-07 30.7 0.1 1.9 2 0 0 2 2 2 1 RF-1 domain Phostensin_N PF13916.6 AIO00572.1 - 0.02 15.2 1.6 7 7.1 0.4 2.6 2 0 0 2 2 2 0 PP1-regulatory protein, Phostensin N-terminal DUF4774 PF15999.5 AIO00572.1 - 0.23 11.3 1.8 0.99 9.3 0.0 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4774) MgtE_N PF03448.17 AIO00572.1 - 0.23 12.1 0.7 0.55 10.9 0.7 1.5 1 0 0 1 1 1 0 MgtE intracellular N domain p450 PF00067.22 AIO00573.1 - 1.6e-48 165.7 0.0 2.1e-48 165.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Mago_nashi PF02792.14 AIO00574.1 - 1.3e-59 200.4 0.1 1.4e-59 200.2 0.1 1.0 1 0 0 1 1 1 1 Mago nashi protein zf-CCCH PF00642.24 AIO00575.1 - 3.5e-06 26.8 1.4 8e-06 25.6 1.4 1.6 1 1 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 AIO00575.1 - 1.1 9.4 6.3 0.28 11.3 1.1 2.2 2 0 0 2 2 2 0 Zinc finger domain Pkinase PF00069.25 AIO00576.1 - 7.9e-34 117.2 0.0 8.3e-18 64.7 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 AIO00576.1 - 4.4e-10 39.3 0.0 7e-05 22.2 0.0 2.4 2 0 0 2 2 2 2 Protein tyrosine kinase Ribosomal_S11 PF00411.19 AIO00577.1 - 2.4e-47 159.9 1.3 3e-47 159.6 1.3 1.1 1 0 0 1 1 1 1 Ribosomal protein S11 ATP-synt_DE_N PF02823.16 AIO00578.1 - 7.8e-13 48.1 0.0 1.3e-12 47.4 0.0 1.3 1 0 0 1 1 1 1 ATP synthase, Delta/Epsilon chain, beta-sandwich domain DUF773 PF05600.12 AIO00579.1 - 4.8e-15 55.3 11.2 4.1e-08 32.4 0.8 3.7 1 1 2 3 3 3 3 CDK5 regulatory subunit-associated protein 3 HEPN_AbiU2 PF18734.1 AIO00579.1 - 0.053 13.0 2.6 0.038 13.5 0.7 1.7 2 0 0 2 2 2 0 AbiU2 ABC_tran_CTD PF16326.5 AIO00579.1 - 0.24 11.7 3.1 17 5.8 0.3 2.9 2 0 0 2 2 2 0 ABC transporter C-terminal domain CENP-F_leu_zip PF10473.9 AIO00579.1 - 0.82 9.7 10.2 0.033 14.2 3.1 2.2 2 1 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Ish1 PF10281.9 AIO00579.1 - 1.4 9.3 4.2 1.4 9.3 0.3 3.0 4 0 0 4 4 4 0 Putative stress-responsive nuclear envelope protein Prefoldin_2 PF01920.20 AIO00579.1 - 1.6 8.7 5.3 2.1 8.3 0.2 3.0 2 2 0 3 3 3 0 Prefoldin subunit Cyclin PF08613.11 AIO00581.1 - 1.3e-21 77.7 0.1 1.3e-21 77.7 0.1 1.4 2 0 0 2 2 2 1 Cyclin Cyclin_N PF00134.23 AIO00581.1 - 1.4e-06 28.0 0.1 2.4e-06 27.3 0.1 1.2 1 0 0 1 1 1 1 Cyclin, N-terminal domain LRR_9 PF14580.6 AIO00582.1 - 4.2e-21 75.2 0.9 1.5e-14 53.9 0.1 2.5 1 1 1 2 2 2 2 Leucine-rich repeat LRR_4 PF12799.7 AIO00582.1 - 1.8e-11 44.1 15.6 1.7e-05 25.1 0.3 3.8 2 1 2 4 4 4 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 AIO00582.1 - 2.4e-11 43.2 27.9 7.6e-06 25.6 5.0 3.5 1 1 3 4 4 4 4 Leucine rich repeat Ribosomal_L15e PF00827.17 AIO00583.1 - 1.8e-85 285.5 8.1 2.1e-85 285.3 8.1 1.0 1 0 0 1 1 1 1 Ribosomal L15 ATP-synt_C PF00137.21 AIO00584.1 - 7.2e-20 71.1 37.0 7.2e-12 45.5 13.6 3.0 3 0 0 3 3 3 2 ATP synthase subunit C SnoaL_2 PF12680.7 AIO00585.1 - 6.7e-05 23.5 0.0 9.3e-05 23.0 0.0 1.5 1 1 0 1 1 1 1 SnoaL-like domain SnoaL_3 PF13474.6 AIO00585.1 - 0.00061 20.1 0.1 0.0017 18.6 0.0 1.7 1 1 1 2 2 2 1 SnoaL-like domain SnoaL PF07366.12 AIO00585.1 - 0.0038 17.0 0.0 0.0051 16.6 0.0 1.4 1 0 0 1 1 1 1 SnoaL-like polyketide cyclase DUF4440 PF14534.6 AIO00585.1 - 0.017 15.5 0.0 0.03 14.7 0.0 1.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4440) DUF16 PF01519.16 AIO00586.1 - 0.11 13.0 0.4 0.11 13.0 0.4 4.0 2 1 1 4 4 4 0 Protein of unknown function DUF16 RET_CLD3 PF17812.1 AIO00586.1 - 0.17 12.1 1.9 2 8.7 0.2 2.5 2 0 0 2 2 2 0 RET Cadherin like domain 3 ABC_tran_CTD PF16326.5 AIO00586.1 - 4.4 7.6 24.4 1.2 9.4 0.5 5.6 4 1 2 6 6 6 0 ABC transporter C-terminal domain DUF3808 PF10300.9 AIO00587.1 - 1.2e-27 96.8 6.1 1.3e-26 93.4 4.8 2.9 2 1 0 2 2 2 1 Protein of unknown function (DUF3808) TPR_12 PF13424.6 AIO00587.1 - 1.2e-07 31.9 0.7 0.00091 19.5 0.1 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 AIO00587.1 - 2.3e-07 30.4 1.0 0.051 13.7 0.0 4.3 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.6 AIO00587.1 - 0.0065 17.2 0.0 27 5.9 0.0 4.5 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.28 AIO00587.1 - 0.0081 16.0 1.6 2.6 8.0 0.1 3.8 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_16 PF13432.6 AIO00587.1 - 0.015 15.9 0.0 9.8 6.9 0.1 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.6 AIO00587.1 - 0.034 14.8 10.7 1.7 9.5 0.3 5.2 6 0 0 6 6 6 0 Tetratricopeptide repeat DUF2225 PF09986.9 AIO00587.1 - 0.047 13.4 5.4 0.16 11.6 1.2 3.0 2 1 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2225) ANAPC3 PF12895.7 AIO00587.1 - 0.075 13.3 7.1 1.1 9.5 0.5 4.8 5 1 1 6 6 6 0 Anaphase-promoting complex, cyclosome, subunit 3 CPSF_A PF03178.15 AIO00589.1 - 3.7e-62 210.5 0.0 6.9e-62 209.6 0.0 1.4 1 0 0 1 1 1 1 CPSF A subunit region MMS1_N PF10433.9 AIO00589.1 - 7.1e-08 31.5 0.0 1.7e-07 30.3 0.0 1.5 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term Ribosomal_60s PF00428.19 AIO00590.1 - 2.4e-23 82.5 7.0 2.8e-23 82.3 7.0 1.0 1 0 0 1 1 1 1 60s Acidic ribosomal protein Ribosomal_60s PF00428.19 AIO00591.1 - 2.4e-23 82.5 7.0 2.8e-23 82.3 7.0 1.0 1 0 0 1 1 1 1 60s Acidic ribosomal protein Meth_synt_2 PF01717.18 AIO00593.1 - 4.2e-153 509.3 0.0 2.3e-144 480.6 0.0 2.2 2 0 0 2 2 2 2 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.12 AIO00593.1 - 1.2e-120 402.8 0.0 8.7e-113 376.9 0.0 2.7 3 0 0 3 3 3 2 Cobalamin-independent synthase, N-terminal domain MIP PF00230.20 AIO00594.1 - 2e-51 174.9 11.0 2.4e-51 174.6 11.0 1.0 1 0 0 1 1 1 1 Major intrinsic protein NiFe_hyd_3_EhaA PF17367.2 AIO00594.1 - 0.13 12.5 2.0 0.27 11.4 0.1 2.3 2 0 0 2 2 2 0 NiFe-hydrogenase-type-3 Eha complex subunit A RINGv PF12906.7 AIO00595.1 - 2.8e-11 43.3 5.6 2.8e-11 43.3 5.6 2.1 2 0 0 2 2 2 1 RING-variant domain MFS_2 PF13347.6 AIO00596.1 - 0.00067 18.3 16.0 0.00067 18.3 16.0 2.5 1 1 1 2 2 2 1 MFS/sugar transport protein DUF4534 PF15049.6 AIO00596.1 - 0.024 14.4 1.6 0.024 14.4 1.6 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF4534) BT1 PF03092.16 AIO00596.1 - 0.035 12.3 19.9 0.096 10.9 7.0 2.9 1 1 0 2 2 2 0 BT1 family Pro_isomerase PF00160.21 AIO00597.1 - 3.7e-44 150.8 0.0 4.8e-44 150.4 0.0 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD ResIII PF04851.15 AIO00599.1 - 2.1e-16 60.4 0.0 5.6e-16 59.0 0.0 1.6 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 AIO00599.1 - 3.2e-09 37.1 0.0 9.2e-09 35.6 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain T5orf172 PF10544.9 AIO00599.1 - 9.9e-09 35.7 0.0 2.3e-08 34.5 0.0 1.5 1 0 0 1 1 1 1 T5orf172 domain DEAD PF00270.29 AIO00599.1 - 1.5e-07 31.4 0.0 2.5e-07 30.6 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Jas PF16135.5 AIO00599.1 - 0.023 14.9 0.1 0.089 13.0 0.1 2.0 1 0 0 1 1 1 0 TPL-binding domain in jasmonate signalling OrsD PF12013.8 AIO00599.1 - 0.076 13.5 0.6 0.27 11.7 0.6 2.0 1 0 0 1 1 1 0 Orsellinic acid/F9775 biosynthesis cluster protein D zf-CCCH_4 PF18044.1 AIO00600.1 - 0.00019 21.1 10.1 0.0011 18.7 5.0 2.4 2 0 0 2 2 2 2 CCCH-type zinc finger zf_CCCH_4 PF18345.1 AIO00600.1 - 0.00035 20.5 1.0 0.00035 20.5 1.0 2.4 2 0 0 2 2 2 1 Zinc finger domain zf-CCCH PF00642.24 AIO00600.1 - 0.0004 20.2 10.8 0.0051 16.7 4.9 2.5 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.6 AIO00600.1 - 0.54 10.8 7.7 2.7 8.6 2.5 2.8 2 1 0 2 2 2 0 RNA-binding, Nab2-type zinc finger Torus PF16131.5 AIO00600.1 - 4.4 8.1 7.4 0.43 11.3 2.4 1.9 2 0 0 2 2 2 0 Torus domain Peptidase_M22 PF00814.25 AIO00602.1 - 2.8e-84 283.1 0.0 3.3e-84 282.8 0.0 1.0 1 0 0 1 1 1 1 Glycoprotease family VCBS PF13517.6 AIO00603.1 - 2.8e-13 50.2 13.7 0.00082 19.9 5.1 6.6 5 1 2 7 7 7 6 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella PQQ_2 PF13360.6 AIO00603.1 - 0.00021 20.9 0.1 0.56 9.7 0.0 2.6 1 1 0 2 2 2 2 PQQ-like domain FG-GAP PF01839.23 AIO00603.1 - 0.001 19.1 22.4 0.59 10.3 3.5 5.8 5 0 0 5 5 5 4 FG-GAP repeat PQQ_3 PF13570.6 AIO00603.1 - 0.058 13.9 18.3 21 5.8 0.1 6.7 6 1 1 7 7 7 0 PQQ-like domain BBS2_C PF14782.6 AIO00603.1 - 0.15 10.8 0.1 5.6 5.6 0.0 2.7 3 0 0 3 3 3 0 Ciliary BBSome complex subunit 2, C-terminal DUF2757 PF10955.8 AIO00605.1 - 0.038 14.3 1.1 0.15 12.3 0.5 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2757) Filament PF00038.21 AIO00605.1 - 0.16 11.6 69.5 0.046 13.3 30.2 3.8 1 1 2 3 3 3 0 Intermediate filament protein DUF812 PF05667.11 AIO00605.1 - 0.55 9.0 58.0 1.5 7.6 21.9 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF812) PMC2NT PF08066.12 AIO00605.1 - 0.69 10.6 6.9 0.21 12.3 0.3 3.7 3 1 1 4 4 4 0 PMC2NT (NUC016) domain UCH PF00443.29 AIO00606.1 - 2.7e-41 141.8 0.0 3.9e-41 141.3 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 AIO00606.1 - 9.9e-11 41.8 0.1 1.7e-09 37.7 0.1 2.0 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase ubiquitin PF00240.23 AIO00606.1 - 4.7e-09 35.9 0.0 2e-08 33.8 0.0 2.0 1 1 0 1 1 1 1 Ubiquitin family Peptidase_C98 PF15499.6 AIO00606.1 - 0.0029 17.1 0.1 1.9 7.9 0.0 2.4 2 1 0 2 2 2 2 Ubiquitin-specific peptidase-like, SUMO isopeptidase Ubiquitin_2 PF14560.6 AIO00606.1 - 0.025 15.0 0.0 0.066 13.7 0.0 1.7 1 0 0 1 1 1 0 Ubiquitin-like domain RNA_pol_Rpb2_6 PF00562.28 AIO00608.1 - 8.6e-121 403.7 0.0 1.1e-120 403.3 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 AIO00608.1 - 7.6e-42 143.1 0.0 1.1e-41 142.6 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_7 PF04560.20 AIO00608.1 - 1.5e-31 108.6 0.0 6.5e-31 106.6 0.1 2.1 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_2 PF04561.14 AIO00608.1 - 9.4e-24 84.1 0.0 1.7e-23 83.2 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_4 PF04566.13 AIO00608.1 - 8.7e-23 80.4 1.9 1.8e-22 79.4 1.9 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_3 PF04565.16 AIO00608.1 - 7.4e-21 74.1 0.1 7.4e-21 74.1 0.1 2.3 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_5 PF04567.17 AIO00608.1 - 4.3e-09 36.8 0.6 1.1e-08 35.5 0.6 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 C1_1 PF00130.22 AIO00608.1 - 0.14 12.1 1.8 0.31 10.9 1.8 1.5 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) OrfB_Zn_ribbon PF07282.11 AIO00608.1 - 0.32 11.0 3.1 0.32 11.0 1.2 1.9 2 0 0 2 2 2 0 Putative transposase DNA-binding domain Myb_DNA-binding PF00249.31 AIO00610.1 - 0.044 14.0 0.0 0.12 12.6 0.0 1.7 2 0 0 2 2 2 0 Myb-like DNA-binding domain Complex1_30kDa PF00329.19 AIO00610.1 - 0.079 13.6 0.1 0.27 11.9 0.1 1.9 1 1 0 1 1 1 0 Respiratory-chain NADH dehydrogenase, 30 Kd subunit Methyltr_RsmB-F PF01189.17 AIO00611.1 - 1e-67 227.6 0.0 2e-67 226.8 0.0 1.5 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F Methyltr_RsmF_N PF17125.5 AIO00611.1 - 8.1e-08 32.7 0.0 2.9e-07 30.9 0.0 2.0 2 0 0 2 2 2 1 N-terminal domain of 16S rRNA methyltransferase RsmF FtsJ PF01728.19 AIO00611.1 - 0.0011 19.1 0.0 0.0033 17.5 0.0 1.7 1 1 0 2 2 2 1 FtsJ-like methyltransferase PCMT PF01135.19 AIO00611.1 - 0.039 13.7 0.0 0.064 13.0 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Kinesin_assoc PF16183.5 AIO00611.1 - 0.074 13.2 1.4 0.27 11.4 1.4 1.9 1 0 0 1 1 1 0 Kinesin-associated CorA PF01544.18 AIO00611.1 - 2.8 7.2 4.9 5.3 6.3 4.9 1.4 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein WD40 PF00400.32 AIO00612.1 - 3e-12 46.8 9.0 0.034 15.0 0.1 7.3 7 0 0 7 7 7 2 WD domain, G-beta repeat NLE PF08154.12 AIO00612.1 - 2.5e-10 40.7 0.1 4.5e-10 39.9 0.1 1.4 1 0 0 1 1 1 1 NLE (NUC135) domain ANAPC4_WD40 PF12894.7 AIO00612.1 - 0.00035 20.8 0.1 2 8.8 0.0 4.0 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Lactonase PF10282.9 AIO00612.1 - 0.11 11.8 0.0 0.23 10.7 0.0 1.4 1 0 0 1 1 1 0 Lactonase, 7-bladed beta-propeller CLP1_P PF16575.5 AIO00613.1 - 2.8e-10 40.3 0.0 1.1e-09 38.4 0.0 1.9 2 0 0 2 2 2 1 mRNA cleavage and polyadenylation factor CLP1 P-loop CLP1_N PF16573.5 AIO00613.1 - 3.7e-09 36.7 0.0 6.8e-09 35.8 0.0 1.5 1 0 0 1 1 1 1 N-terminal beta-sandwich domain of polyadenylation factor Clp1 PF06807.14 AIO00613.1 - 0.00033 21.0 0.0 0.0007 20.0 0.0 1.5 1 0 0 1 1 1 1 Pre-mRNA cleavage complex II protein Clp1 DUF4746 PF15928.5 AIO00614.1 - 0.0042 16.5 11.6 0.0063 16.0 11.6 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4746) TFIIF_alpha PF05793.12 AIO00614.1 - 0.0075 14.9 15.5 0.0083 14.8 15.5 1.1 1 0 0 1 1 1 1 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Nop14 PF04147.12 AIO00614.1 - 0.02 13.1 19.9 0.023 12.9 19.9 1.1 1 0 0 1 1 1 0 Nop14-like family Tim54 PF11711.8 AIO00614.1 - 0.03 13.1 2.3 0.034 12.9 2.3 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 SpoIIIAH PF12685.7 AIO00614.1 - 0.034 14.0 6.1 0.042 13.7 6.1 1.3 1 0 0 1 1 1 0 SpoIIIAH-like protein SDA1 PF05285.12 AIO00614.1 - 0.037 13.4 18.4 0.042 13.3 18.4 1.2 1 0 0 1 1 1 0 SDA1 Spore_coat_CotO PF14153.6 AIO00614.1 - 0.27 11.1 10.2 0.32 10.9 10.2 1.2 1 0 0 1 1 1 0 Spore coat protein CotO RPN2_C PF18004.1 AIO00614.1 - 0.31 10.9 5.4 0.48 10.3 5.4 1.3 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain NOA36 PF06524.12 AIO00614.1 - 0.44 9.8 28.2 0.56 9.5 28.2 1.1 1 0 0 1 1 1 0 NOA36 protein NPR3 PF03666.13 AIO00614.1 - 0.46 9.2 5.7 0.52 9.1 5.7 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Zip PF02535.22 AIO00614.1 - 0.55 9.4 1.9 0.55 9.4 1.9 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter CDC45 PF02724.14 AIO00614.1 - 1 7.6 13.3 1.2 7.3 13.3 1.2 1 0 0 1 1 1 0 CDC45-like protein Presenilin PF01080.17 AIO00614.1 - 2.4 6.9 6.3 2.6 6.7 6.3 1.1 1 0 0 1 1 1 0 Presenilin RR_TM4-6 PF06459.12 AIO00614.1 - 3.4 7.4 7.2 4.9 6.9 7.2 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Afi1 PF07792.12 AIO00614.1 - 3.8 8.0 11.1 7.5 7.0 11.1 1.5 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking Cwf_Cwc_15 PF04889.12 AIO00614.1 - 6.4 6.4 28.1 9.8 5.8 28.1 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein DUF913 PF06025.12 AIO00614.1 - 7 5.5 7.4 9.9 5.0 7.4 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) PilM PF07419.12 AIO00615.1 - 0.022 14.9 0.2 4.4 7.5 0.0 2.7 2 0 0 2 2 2 0 PilM DUF2935 PF11155.8 AIO00615.1 - 0.16 12.3 22.9 0.22 11.8 0.0 6.7 3 3 0 3 3 3 0 Domain of unknown function (DUF2935) Cupin_4 PF08007.12 AIO00616.1 - 2.6e-41 142.1 0.2 5.3e-41 141.1 0.2 1.4 1 1 0 1 1 1 1 Cupin superfamily protein Cupin_8 PF13621.6 AIO00616.1 - 6.9e-07 29.2 0.1 1.2e-05 25.2 0.1 2.6 1 1 0 1 1 1 1 Cupin-like domain Cupin_2 PF07883.11 AIO00616.1 - 0.031 14.0 0.0 0.083 12.6 0.0 1.7 1 0 0 1 1 1 0 Cupin domain JmjC PF02373.22 AIO00616.1 - 0.044 14.2 0.0 0.12 12.9 0.0 1.8 1 0 0 1 1 1 0 JmjC domain, hydroxylase Helicase_C PF00271.31 AIO00617.1 - 2.1e-10 40.9 0.0 5.4e-10 39.6 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 AIO00617.1 - 2.4e-06 27.4 0.0 6.3e-06 26.1 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase Phage_portal_2 PF05136.13 AIO00617.1 - 0.0054 15.9 0.7 0.012 14.9 0.7 1.5 1 0 0 1 1 1 1 Phage portal protein, lambda family COPIIcoated_ERV PF07970.12 AIO00618.1 - 2.3e-18 66.8 0.0 3.7e-18 66.2 0.0 1.3 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.6 AIO00618.1 - 5.9e-08 33.0 0.0 1.1e-07 32.1 0.0 1.4 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) Kinesin PF00225.23 AIO00619.1 - 6.1e-88 294.9 0.0 8.8e-88 294.4 0.0 1.2 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 AIO00619.1 - 9.6e-17 61.3 0.0 1.6e-16 60.5 0.0 1.3 1 0 0 1 1 1 1 Microtubule binding TMF_DNA_bd PF12329.8 AIO00619.1 - 1.8 8.6 4.1 0.84 9.7 0.2 2.4 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding CRAL_TRIO PF00650.20 AIO00620.1 - 7e-11 42.1 0.0 1.3e-10 41.3 0.0 1.4 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO PF00650.20 AIO00621.1 - 3.1e-13 49.7 0.0 5.3e-13 49.0 0.0 1.4 1 0 0 1 1 1 1 CRAL/TRIO domain Aa_trans PF01490.18 AIO00622.1 - 1.8e-42 145.5 35.0 2.2e-42 145.2 35.0 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 AIO00622.1 - 2.5e-10 40.0 20.9 6.1e-10 38.7 20.9 1.6 1 0 0 1 1 1 1 Tryptophan/tyrosine permease family AA_permease_2 PF13520.6 AIO00622.1 - 2e-08 33.5 25.1 2e-08 33.5 25.1 2.0 2 0 0 2 2 2 1 Amino acid permease VIT1 PF01988.19 AIO00622.1 - 0.0096 15.8 0.0 0.0096 15.8 0.0 3.3 3 0 0 3 3 3 1 VIT family BNIP2 PF12496.8 AIO00622.1 - 0.11 12.9 1.0 0.18 12.3 1.0 1.3 1 0 0 1 1 1 0 Bcl2-/adenovirus E1B nineteen kDa-interacting protein 2 DUF2207 PF09972.9 AIO00622.1 - 1.5 7.5 0.0 1.5 7.5 0.0 3.1 3 0 0 3 3 3 0 Predicted membrane protein (DUF2207) Aa_trans PF01490.18 AIO00623.1 - 4.2e-50 170.6 27.9 5e-50 170.4 27.9 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 AIO00623.1 - 1.6e-07 30.8 10.5 1.6e-07 30.8 10.5 2.1 2 0 0 2 2 2 1 Tryptophan/tyrosine permease family Aa_trans PF01490.18 AIO00624.1 - 6e-48 163.6 33.9 7.1e-48 163.3 33.9 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 AIO00624.1 - 1.2e-06 27.8 19.1 1.2e-06 27.8 19.1 2.2 1 1 1 2 2 2 1 Tryptophan/tyrosine permease family CRAL_TRIO PF00650.20 AIO00625.1 - 6.3e-13 48.7 0.0 1.2e-12 47.9 0.0 1.5 1 0 0 1 1 1 1 CRAL/TRIO domain DUF2189 PF09955.9 AIO00626.1 - 0.031 14.5 0.0 0.073 13.3 0.0 1.7 1 0 0 1 1 1 0 Predicted integral membrane protein (DUF2189) Kinase-PPPase PF03618.14 AIO00626.1 - 0.084 12.6 1.5 0.13 12.0 0.5 1.8 2 0 0 2 2 2 0 Kinase/pyrophosphorylase Peptidase_C2 PF00648.21 AIO00628.1 - 1.6e-46 158.7 0.0 2.1e-46 158.3 0.0 1.2 1 0 0 1 1 1 1 Calpain family cysteine protease DUF1935 PF09149.10 AIO00628.1 - 1.8e-25 89.3 0.0 3.2e-25 88.5 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1935) Peptidase_C2 PF00648.21 AIO00629.1 - 8.3e-30 103.8 0.0 1.5e-29 103.0 0.0 1.4 1 0 0 1 1 1 1 Calpain family cysteine protease DUF1935 PF09149.10 AIO00629.1 - 4.1e-13 49.6 0.0 1.1e-12 48.2 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1935) DUF1935 PF09149.10 AIO00630.1 - 4e-18 65.7 0.0 7.5e-18 64.8 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1935) Peptidase_C2 PF00648.21 AIO00630.1 - 3.8e-16 59.0 0.0 5.8e-16 58.4 0.0 1.3 1 0 0 1 1 1 1 Calpain family cysteine protease Peptidase_C2 PF00648.21 AIO00631.1 - 4.5e-36 124.4 0.0 7.3e-36 123.7 0.0 1.3 1 0 0 1 1 1 1 Calpain family cysteine protease DUF1935 PF09149.10 AIO00631.1 - 2.9e-21 75.8 0.1 5.1e-21 75.0 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1935) Peptidase_C2 PF00648.21 AIO00632.1 - 6.9e-50 169.7 0.0 9.9e-50 169.2 0.0 1.2 1 0 0 1 1 1 1 Calpain family cysteine protease DUF1935 PF09149.10 AIO00632.1 - 4.1e-15 56.0 0.0 1.1e-14 54.7 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1935) RRF PF01765.19 AIO00632.1 - 0.017 15.1 0.0 0.029 14.3 0.0 1.3 1 0 0 1 1 1 0 Ribosome recycling factor Peptidase_C2 PF00648.21 AIO00633.1 - 2.4e-66 223.8 0.1 3.1e-66 223.4 0.1 1.1 1 0 0 1 1 1 1 Calpain family cysteine protease DUF1935 PF09149.10 AIO00633.1 - 1.9e-17 63.5 0.2 4.5e-17 62.3 0.2 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1935) WYL_2 PF10902.8 AIO00633.1 - 0.048 14.0 0.6 1.5 9.3 0.1 2.5 2 0 0 2 2 2 0 WYL_2, Sm-like SH3 beta-barrel fold AAA_16 PF13191.6 AIO00634.1 - 0.005 17.2 0.1 0.012 16.0 0.1 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_14 PF13173.6 AIO00634.1 - 0.067 13.2 0.0 0.1 12.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain Sulfotransfer_4 PF17784.1 AIO00635.1 - 4.1e-40 137.9 0.0 1e-39 136.6 0.0 1.6 1 1 0 1 1 1 1 Sulfotransferase domain cNMP_binding PF00027.29 AIO00636.1 - 1.5e-21 76.2 0.2 6.3e-07 29.4 0.0 5.9 4 2 1 5 5 5 4 Cyclic nucleotide-binding domain DnaJ PF00226.31 AIO00638.1 - 7.9e-21 74.0 0.2 1.5e-20 73.0 0.2 1.5 1 0 0 1 1 1 1 DnaJ domain DnaJ-X PF14308.6 AIO00638.1 - 0.00042 19.8 0.5 0.00074 19.0 0.5 1.3 1 0 0 1 1 1 1 X-domain of DnaJ-containing TRM13 PF05206.14 AIO00639.1 - 3.6e-37 128.3 0.0 7.7e-25 87.9 0.0 3.1 1 1 1 2 2 2 2 Methyltransferase TRM13 zf-U11-48K PF05253.12 AIO00639.1 - 3.8e-10 39.5 1.6 3.8e-10 39.5 1.6 1.9 2 0 0 2 2 2 1 U11-48K-like CHHC zinc finger zf-TRM13_CCCH PF11722.8 AIO00639.1 - 6.6e-08 32.2 10.1 6.6e-08 32.2 10.1 2.3 2 0 0 2 2 2 1 CCCH zinc finger in TRM13 protein Methyltransf_32 PF13679.6 AIO00639.1 - 3.3 7.7 6.0 48 3.9 6.0 2.4 1 1 0 1 1 1 0 Methyltransferase domain ABC_membrane_2 PF06472.15 AIO00641.1 - 4.1e-69 233.0 4.9 6e-69 232.4 4.9 1.3 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 ABC_tran PF00005.27 AIO00641.1 - 4.2e-16 59.7 0.0 7.8e-16 58.8 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 AIO00641.1 - 0.043 13.6 0.0 0.067 13.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 AIO00641.1 - 0.24 11.9 0.1 0.41 11.1 0.1 1.3 1 0 0 1 1 1 0 AAA domain Atg14 PF10186.9 AIO00642.1 - 0.021 13.9 16.7 0.1 11.7 0.9 3.6 3 1 0 3 3 3 0 Vacuolar sorting 38 and autophagy-related subunit 14 Apt1 PF10351.9 AIO00642.1 - 0.049 12.5 2.5 0.12 11.2 2.5 1.5 1 0 0 1 1 1 0 Golgi-body localisation protein domain MPS2 PF17060.5 AIO00642.1 - 0.43 9.8 10.2 0.2 10.9 2.3 2.2 2 0 0 2 2 2 0 Monopolar spindle protein 2 DUF501 PF04417.12 AIO00642.1 - 1.7 8.4 9.7 0.58 10.0 2.0 3.5 2 1 1 3 3 3 0 Protein of unknown function (DUF501) BBP1_C PF15272.6 AIO00642.1 - 2 8.2 5.3 0.47 10.2 0.8 2.2 2 0 0 2 2 2 0 Spindle pole body component BBP1, C-terminal V-SNARE PF05008.15 AIO00642.1 - 5.4 7.5 9.7 20 5.7 1.3 3.2 2 0 0 2 2 2 0 Vesicle transport v-SNARE protein N-terminus GHMP_kinases_C PF08544.13 AIO00643.1 - 3.5e-16 59.4 0.5 6.7e-16 58.4 0.5 1.5 1 0 0 1 1 1 1 GHMP kinases C terminal GHMP_kinases_N PF00288.26 AIO00643.1 - 4.6e-12 46.0 0.7 1.1e-11 44.7 0.7 1.7 1 0 0 1 1 1 1 GHMP kinases N terminal domain Scaffolding_pro PF11418.8 AIO00643.1 - 0.15 12.6 0.0 0.29 11.7 0.0 1.4 1 0 0 1 1 1 0 Phi29 scaffolding protein YcaO PF02624.16 AIO00643.1 - 0.17 11.1 0.0 0.34 10.2 0.0 1.5 1 0 0 1 1 1 0 YcaO cyclodehydratase, ATP-ad Mg2+-binding Aa_trans PF01490.18 AIO00644.1 - 1.8e-46 158.7 40.5 2.2e-46 158.4 40.5 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 AIO00644.1 - 1.5e-09 37.4 17.7 1.5e-09 37.4 17.7 2.2 1 1 0 2 2 2 1 Tryptophan/tyrosine permease family Aa_trans PF01490.18 AIO00645.1 - 1.6e-45 155.6 36.0 1.9e-45 155.3 36.0 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein AA_permease_2 PF13520.6 AIO00645.1 - 1.3e-05 24.3 15.4 1.3e-05 24.3 15.4 2.7 1 1 2 3 3 3 2 Amino acid permease Trp_Tyr_perm PF03222.13 AIO00645.1 - 1.3e-05 24.4 14.3 1.3e-05 24.4 14.3 2.6 2 2 0 2 2 2 1 Tryptophan/tyrosine permease family Cytochrom_B_C PF00032.17 AIO00645.1 - 2.2 8.6 7.4 0.16 12.3 0.4 2.7 3 0 0 3 3 3 0 Cytochrome b(C-terminal)/b6/petD Aa_trans PF01490.18 AIO00646.1 - 2.7e-44 151.5 33.8 3.5e-44 151.2 33.8 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein FA_hydroxylase PF04116.13 AIO00647.1 - 3.7e-15 56.4 13.0 3.7e-15 56.4 13.0 1.7 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily Ribosomal_L7Ae PF01248.26 AIO00649.1 - 8.6e-05 22.2 0.1 0.00023 20.8 0.1 1.7 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Antimicrobial19 PF08225.11 AIO00649.1 - 0.031 13.9 0.1 0.069 12.8 0.1 1.5 1 0 0 1 1 1 0 Pseudin antimicrobial peptide XTBD PF11952.8 AIO00651.1 - 0.053 13.3 0.0 0.21 11.4 0.0 2.1 1 0 0 1 1 1 0 XRN-Two Binding Domain, XTBD Cas6 PF09559.10 AIO00652.1 - 0.046 13.7 0.7 5.4 6.9 0.3 2.9 2 0 0 2 2 2 0 Cas6 Crispr FtsJ PF01728.19 AIO00653.1 - 4.5e-38 131.1 0.0 5.7e-38 130.8 0.0 1.1 1 0 0 1 1 1 1 FtsJ-like methyltransferase HrpB7 PF09486.10 AIO00654.1 - 0.11 12.9 2.2 0.3 11.5 2.2 1.7 1 0 0 1 1 1 0 Bacterial type III secretion protein (HrpB7) C2 PF00168.30 AIO00656.1 - 1.1e-22 80.3 0.0 1.6e-22 79.8 0.0 1.2 1 0 0 1 1 1 1 C2 domain CEP76-C2 PF15627.6 AIO00656.1 - 0.029 14.0 0.0 0.045 13.3 0.0 1.3 1 1 0 1 1 1 0 CEP76 C2 domain DOCK-C2 PF14429.6 AIO00656.1 - 0.051 13.4 0.0 0.091 12.6 0.0 1.4 1 0 0 1 1 1 0 C2 domain in Dock180 and Zizimin proteins Peptidase_M41 PF01434.18 AIO00658.1 - 2.5e-44 151.4 0.0 6.9e-44 150.0 0.0 1.8 1 1 0 1 1 1 1 Peptidase family M41 AAA PF00004.29 AIO00658.1 - 1.6e-33 115.9 0.0 3.3e-33 114.9 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 AIO00658.1 - 2.3e-11 43.3 0.1 5.6e-11 42.1 0.1 1.6 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 AIO00658.1 - 0.0013 18.8 0.6 0.17 11.9 0.4 2.6 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 AIO00658.1 - 0.0019 18.4 0.0 0.0047 17.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 AIO00658.1 - 0.0022 18.3 0.5 0.57 10.5 0.1 2.8 1 1 0 2 2 2 1 AAA domain AAA_16 PF13191.6 AIO00658.1 - 0.0073 16.7 0.7 0.029 14.8 0.1 2.4 1 1 1 2 2 2 1 AAA ATPase domain AAA_18 PF13238.6 AIO00658.1 - 0.013 16.0 0.1 0.047 14.2 0.0 1.9 2 0 0 2 2 2 0 AAA domain RuvB_N PF05496.12 AIO00658.1 - 0.03 14.1 0.0 0.082 12.6 0.0 1.7 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain IstB_IS21 PF01695.17 AIO00658.1 - 0.041 13.6 0.0 0.098 12.4 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_33 PF13671.6 AIO00658.1 - 0.088 13.0 0.0 0.26 11.4 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 AIO00658.1 - 0.091 13.0 0.4 0.33 11.2 0.0 2.2 2 0 0 2 2 2 0 AAA domain Mg_chelatase PF01078.21 AIO00658.1 - 0.11 11.9 0.3 0.22 10.9 0.3 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Nodulin-like PF06813.13 AIO00660.1 - 9.3e-06 25.3 8.4 1.3e-05 24.8 8.4 1.2 1 0 0 1 1 1 1 Nodulin-like MFS_1 PF07690.16 AIO00661.1 - 9e-09 34.7 50.4 1.7e-07 30.5 24.5 3.9 2 2 1 3 3 3 2 Major Facilitator Superfamily Nodulin-like PF06813.13 AIO00661.1 - 0.0052 16.3 18.8 0.076 12.5 18.8 2.3 1 1 0 1 1 1 1 Nodulin-like CesT PF05932.13 AIO00663.1 - 1.8e-15 57.1 1.0 4e-15 56.0 0.1 1.9 2 0 0 2 2 2 1 Tir chaperone protein (CesT) family DivIC PF04977.15 AIO00663.1 - 0.016 15.0 1.0 0.033 13.9 1.0 1.4 1 0 0 1 1 1 0 Septum formation initiator DUF4407 PF14362.6 AIO00663.1 - 0.016 14.5 0.9 0.021 14.2 0.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF1192 PF06698.11 AIO00663.1 - 0.075 13.1 0.6 7.7 6.7 0.7 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) ubiquitin PF00240.23 AIO00663.1 - 0.086 12.6 0.0 0.25 11.1 0.0 1.8 2 0 0 2 2 2 0 Ubiquitin family PGBA_C PF15437.6 AIO00665.1 - 0.02 15.3 3.4 0.052 13.9 3.4 1.7 1 0 0 1 1 1 0 Plasminogen-binding protein pgbA C-terminal PTA_PTB PF01515.19 AIO00665.1 - 0.036 13.4 0.2 0.09 12.1 0.0 1.6 1 1 0 1 1 1 0 Phosphate acetyl/butaryl transferase Enkurin PF13864.6 AIO00665.1 - 6.6 7.2 8.5 46 4.5 3.0 3.0 3 1 0 3 3 3 0 Calmodulin-binding C2 PF00168.30 AIO00666.1 - 1.3e-19 70.3 0.2 2.4e-19 69.5 0.2 1.4 1 0 0 1 1 1 1 C2 domain DOCK-C2 PF14429.6 AIO00666.1 - 0.031 14.1 0.0 0.051 13.4 0.0 1.3 1 0 0 1 1 1 0 C2 domain in Dock180 and Zizimin proteins C2 PF00168.30 AIO00667.1 - 1.2e-20 73.7 0.1 1.6e-20 73.3 0.1 1.2 1 0 0 1 1 1 1 C2 domain Vpu PF00558.19 AIO00668.1 - 2 8.3 3.7 12 5.8 0.2 2.7 2 0 0 2 2 2 0 Vpu protein TRIQK PF15168.6 AIO00668.1 - 2.3 8.2 4.4 14 5.7 0.9 2.8 2 0 0 2 2 2 0 Triple QxxK/R motif-containing protein family Ras PF00071.22 AIO00671.1 - 3.4e-23 82.0 0.5 6.4e-19 68.1 0.0 2.6 2 1 0 2 2 2 2 Ras family Roc PF08477.13 AIO00671.1 - 1.3e-15 57.7 0.1 3.2e-09 37.0 0.0 2.4 1 1 1 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase GTP_EFTU PF00009.27 AIO00671.1 - 2.5e-08 33.7 0.4 4.4e-08 32.9 0.4 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Arf PF00025.21 AIO00671.1 - 2.8e-08 33.4 0.0 2.2e-06 27.2 0.0 2.3 2 0 0 2 2 2 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 AIO00671.1 - 1.8e-06 27.5 0.1 3.3e-06 26.6 0.1 1.5 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 AIO00671.1 - 6.5e-05 23.0 0.1 0.0013 18.8 0.1 2.8 2 1 0 2 2 2 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 AIO00671.1 - 0.32 11.0 1.8 1.7 8.7 0.7 2.4 2 0 0 2 2 2 0 Dynamin family Aa_trans PF01490.18 AIO00672.1 - 5.2e-49 167.0 31.1 6.1e-49 166.8 31.1 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 AIO00672.1 - 2e-07 30.4 30.8 7e-07 28.6 30.8 1.7 1 1 0 1 1 1 1 Tryptophan/tyrosine permease family AA_permease_2 PF13520.6 AIO00672.1 - 4.5e-05 22.5 25.8 4.5e-05 22.5 25.8 1.8 2 0 0 2 2 2 1 Amino acid permease Aa_trans PF01490.18 AIO00673.1 - 5.2e-49 167.0 31.1 6.1e-49 166.8 31.1 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 AIO00673.1 - 2e-07 30.4 30.8 7e-07 28.6 30.8 1.7 1 1 0 1 1 1 1 Tryptophan/tyrosine permease family AA_permease_2 PF13520.6 AIO00673.1 - 4.5e-05 22.5 25.8 4.5e-05 22.5 25.8 1.8 2 0 0 2 2 2 1 Amino acid permease KIAA1430 PF13879.6 AIO00674.1 - 9.2e-18 64.9 0.3 1.4e-17 64.3 0.3 1.3 1 0 0 1 1 1 1 KIAA1430 homologue HCMV_UL139 PF12507.8 AIO00674.1 - 0.037 14.4 0.1 0.037 14.4 0.1 1.6 2 0 0 2 2 2 0 Human Cytomegalovirus UL139 protein Bax1-I PF01027.20 AIO00675.1 - 0.0088 15.9 0.6 0.0097 15.8 0.6 1.0 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 DUF2427 PF10348.9 AIO00675.1 - 0.019 14.7 0.6 0.025 14.4 0.5 1.2 1 1 0 1 1 1 0 Domain of unknown function (DUF2427) WCOR413 PF05562.11 AIO00675.1 - 0.023 14.6 0.1 0.039 13.9 0.0 1.4 1 1 0 1 1 1 0 Cold acclimation protein WCOR413 LapA_dom PF06305.11 AIO00675.1 - 0.52 10.2 3.8 0.94 9.3 3.8 1.6 1 1 0 1 1 1 0 Lipopolysaccharide assembly protein A domain PepSY_TM_like_2 PF16357.5 AIO00675.1 - 2 8.4 4.0 2.4 8.1 4.0 1.1 1 0 0 1 1 1 0 Putative PepSY_TM-like HTH_1 PF00126.27 AIO00678.1 - 0.071 13.1 0.0 0.32 11.0 0.0 2.2 1 0 0 1 1 1 0 Bacterial regulatory helix-turn-helix protein, lysR family SH3BGR PF04908.15 AIO00680.1 - 0.32 11.2 1.7 25 5.1 0.1 2.6 2 0 0 2 2 2 0 SH3-binding, glutamic acid-rich protein DUF4217 PF13959.6 AIO00681.1 - 3.9e-05 23.8 0.0 9.5e-05 22.5 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) DUF4090 PF13319.6 AIO00681.1 - 0.055 13.7 0.0 0.38 11.0 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4090) RRM_1 PF00076.22 AIO00683.1 - 0.00011 21.9 0.0 0.00021 21.1 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) YhfH PF14149.6 AIO00683.1 - 0.011 15.7 1.4 0.25 11.3 0.1 2.5 2 0 0 2 2 2 0 YhfH-like protein SET PF00856.28 AIO00686.1 - 2.2e-05 24.9 0.0 0.00041 20.8 0.0 2.3 1 1 0 1 1 1 1 SET domain BPL_LplA_LipB PF03099.19 AIO00687.1 - 1.6e-11 44.2 0.0 3.2e-11 43.2 0.0 1.4 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family HBS1_N PF08938.10 AIO00687.1 - 0.0099 16.2 0.0 0.021 15.1 0.0 1.5 1 0 0 1 1 1 1 HBS1 N-terminus CM_2 PF01817.21 AIO00687.1 - 0.22 11.9 0.0 0.53 10.7 0.0 1.6 2 0 0 2 2 2 0 Chorismate mutase type II OmpH PF03938.14 AIO00688.1 - 0.057 13.7 0.5 0.1 12.9 0.5 1.4 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) SF-assemblin PF06705.11 AIO00688.1 - 0.06 12.7 1.8 0.1 11.9 1.8 1.3 1 0 0 1 1 1 0 SF-assemblin/beta giardin Apolipoprotein PF01442.18 AIO00688.1 - 0.068 13.0 10.9 0.13 12.2 10.9 1.3 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain Trimer_CC PF08954.11 AIO00688.1 - 0.13 11.9 0.5 0.61 9.7 0.5 2.1 1 0 0 1 1 1 0 Trimerisation motif Baculo_PEP_C PF04513.12 AIO00688.1 - 0.18 11.9 0.3 0.31 11.1 0.3 1.4 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF641 PF04859.12 AIO00688.1 - 1.6 9.1 4.8 3.9 7.8 4.8 1.6 1 1 0 1 1 1 0 Plant protein of unknown function (DUF641) TMPIT PF07851.13 AIO00688.1 - 2.7 7.1 4.8 3.8 6.7 4.8 1.1 1 0 0 1 1 1 0 TMPIT-like protein ABC_tran_CTD PF16326.5 AIO00688.1 - 2.9 8.2 5.4 12 6.2 1.6 2.5 2 0 0 2 2 2 0 ABC transporter C-terminal domain DUF4407 PF14362.6 AIO00688.1 - 3.7 6.8 5.4 5.9 6.1 5.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF4498 PF14926.6 AIO00689.1 - 1.1e-18 67.4 0.0 1.5e-11 44.1 0.0 3.9 3 1 0 3 3 3 2 Domain of unknown function (DUF4498) EMP24_GP25L PF01105.24 AIO00690.1 - 1.8e-24 86.7 0.0 2e-24 86.5 0.0 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD BppU_N PF10651.9 AIO00690.1 - 0.054 13.2 0.0 0.089 12.5 0.0 1.3 1 0 0 1 1 1 0 BppU N-terminal domain Gypsy PF07253.11 AIO00690.1 - 0.056 12.0 0.2 0.068 11.7 0.2 1.0 1 0 0 1 1 1 0 Gypsy protein EMP24_GP25L PF01105.24 AIO00691.1 - 4e-22 79.0 0.1 4.3e-22 78.9 0.1 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD LigT_PEase PF02834.16 AIO00691.1 - 0.12 12.6 0.0 0.36 11.0 0.0 1.8 1 1 1 2 2 2 0 LigT like Phosphoesterase Peptidase_M20 PF01546.28 AIO00692.1 - 6.5e-27 94.6 0.1 8.4e-27 94.2 0.1 1.1 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 AIO00692.1 - 6.9e-07 29.2 0.0 1.9e-06 27.7 0.0 1.7 1 0 0 1 1 1 1 Peptidase dimerisation domain Hydrolase_4 PF12146.8 AIO00693.1 - 2.5e-68 229.9 0.0 3.3e-68 229.5 0.0 1.1 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 AIO00693.1 - 6.8e-16 58.7 0.1 6.1e-13 49.0 0.1 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 AIO00693.1 - 5.4e-13 50.0 0.1 7.4e-13 49.6 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 AIO00693.1 - 1.4e-10 41.1 0.2 1.4e-05 24.7 0.1 2.1 2 0 0 2 2 2 2 Prolyl oligopeptidase family Peptidase_S15 PF02129.18 AIO00693.1 - 2.9e-05 23.8 0.1 0.0025 17.5 0.0 2.1 2 0 0 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) DUF2920 PF11144.8 AIO00693.1 - 0.00014 21.2 0.0 0.062 12.5 0.0 2.9 2 1 0 2 2 2 1 Protein of unknown function (DUF2920) DLH PF01738.18 AIO00693.1 - 0.0013 18.4 0.0 1.1 8.7 0.0 2.3 2 0 0 2 2 2 2 Dienelactone hydrolase family PGAP1 PF07819.13 AIO00693.1 - 0.0027 17.5 0.0 0.0037 17.0 0.0 1.2 1 0 0 1 1 1 1 PGAP1-like protein Palm_thioest PF02089.15 AIO00693.1 - 0.0031 17.4 0.0 0.0046 16.8 0.0 1.3 1 1 0 1 1 1 1 Palmitoyl protein thioesterase PhoPQ_related PF10142.9 AIO00693.1 - 0.0054 15.4 0.0 0.0071 15.0 0.0 1.1 1 0 0 1 1 1 1 PhoPQ-activated pathogenicity-related protein Abhydrolase_8 PF06259.12 AIO00693.1 - 0.0098 15.5 0.0 0.022 14.4 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase Esterase PF00756.20 AIO00693.1 - 0.012 15.2 0.0 0.016 14.9 0.0 1.3 1 0 0 1 1 1 0 Putative esterase Ser_hydrolase PF06821.13 AIO00693.1 - 0.033 14.0 0.0 1 9.2 0.0 2.2 1 1 0 1 1 1 0 Serine hydrolase Abhydrolase_3 PF07859.13 AIO00693.1 - 0.066 13.1 0.0 0.11 12.4 0.0 1.6 1 1 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_5 PF12695.7 AIO00693.1 - 0.1 12.4 0.1 1.1 9.0 0.0 2.3 3 0 0 3 3 3 0 Alpha/beta hydrolase family Thioesterase PF00975.20 AIO00693.1 - 0.15 12.1 0.0 0.35 10.9 0.0 1.6 1 0 0 1 1 1 0 Thioesterase domain LRR_4 PF12799.7 AIO00695.1 - 4.5e-12 46.0 15.7 0.057 13.9 0.0 7.8 5 2 4 9 9 9 6 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 AIO00695.1 - 5.1e-05 22.9 11.2 0.041 13.7 0.2 5.2 6 1 0 6 6 6 3 Leucine rich repeat LRR_9 PF14580.6 AIO00695.1 - 0.031 13.8 3.8 3.2 7.2 0.4 3.9 2 2 2 5 5 5 0 Leucine-rich repeat Cyt-b5 PF00173.28 AIO00696.1 - 1.8e-05 24.8 0.0 3.2e-05 24.0 0.0 1.4 1 1 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Cyt-b5 PF00173.28 AIO00697.1 - 1.1e-07 31.9 0.0 1.6e-07 31.3 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain DUF4335 PF14233.6 AIO00697.1 - 0.0094 15.9 0.3 0.016 15.1 0.3 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4335) Cyt-b5 PF00173.28 AIO00698.1 - 1.4e-06 28.3 0.0 1.9e-06 27.9 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Cyt-b5 PF00173.28 AIO00699.1 - 2.6e-08 33.9 0.0 3.4e-08 33.5 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Cyt-b5 PF00173.28 AIO00700.1 - 1.3e-08 34.9 0.0 1.8e-08 34.4 0.0 1.3 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain DUF3638 PF12340.8 AIO00701.1 - 2.1e-29 102.5 0.0 3.8e-28 98.4 0.0 2.4 1 1 0 1 1 1 1 Protein of unknown function (DUF3638) DUF3645 PF12359.8 AIO00701.1 - 8.3e-16 57.1 0.5 2.7e-15 55.4 0.5 2.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3645) zf-RanBP PF00641.18 AIO00701.1 - 1.1e-07 31.0 22.8 4.1e-05 22.8 5.3 3.5 3 0 0 3 3 3 3 Zn-finger in Ran binding protein and others Thioredoxin_8 PF13905.6 AIO00701.1 - 4.4e-06 26.9 0.0 1.1e-05 25.7 0.0 1.7 1 0 0 1 1 1 1 Thioredoxin-like ubiquitin PF00240.23 AIO00701.1 - 0.0012 18.5 0.0 0.0028 17.4 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin family TMEM51 PF15345.6 AIO00701.1 - 0.2 11.5 0.0 0.2 11.5 0.0 2.2 2 0 0 2 2 2 0 Transmembrane protein 51 H_PPase PF03030.16 AIO00702.1 - 2.8e-238 792.8 28.0 2.8e-238 792.8 28.0 1.3 1 1 0 1 1 1 1 Inorganic H+ pyrophosphatase RP853 PF17542.2 AIO00702.1 - 8.2 5.4 6.9 8.9 5.3 0.1 2.3 2 0 0 2 2 2 0 Uncharacterized RP853 GAIN PF16489.5 AIO00703.1 - 0.0066 15.9 0.1 0.013 14.9 0.1 1.4 1 0 0 1 1 1 1 GPCR-Autoproteolysis INducing (GAIN) domain PilA4 PF18682.1 AIO00703.1 - 0.12 12.7 0.5 0.43 11.0 0.5 1.9 1 0 0 1 1 1 0 Pilin A4 LRR_6 PF13516.6 AIO00703.1 - 1.3 9.3 7.9 6.9 7.0 0.1 4.5 4 0 0 4 4 4 0 Leucine Rich repeat LRR_8 PF13855.6 AIO00703.1 - 5 7.0 8.0 25 4.7 4.1 3.8 2 1 1 3 3 3 0 Leucine rich repeat HTH_23 PF13384.6 AIO00704.1 - 0.013 15.2 0.2 0.043 13.6 0.1 2.0 2 0 0 2 2 2 0 Homeodomain-like domain RILP PF11461.8 AIO00705.1 - 0.062 13.5 8.5 0.8 10.0 1.8 3.6 2 0 0 2 2 2 0 Rab interacting lysosomal protein RseA_C PF03873.13 AIO00705.1 - 1.4 9.2 5.7 12 6.2 0.1 3.8 4 0 0 4 4 4 0 Anti sigma-E protein RseA, C-terminal domain MT PF12777.7 AIO00706.1 - 2.6e-06 26.7 0.1 2.6e-06 26.7 0.1 2.2 2 0 0 2 2 2 1 Microtubule-binding stalk of dynein motor DUF4407 PF14362.6 AIO00706.1 - 0.0028 17.1 22.0 0.22 10.8 16.1 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF4407) DDE_Tnp_ISL3 PF01610.17 AIO00706.1 - 0.024 14.4 1.0 0.071 12.8 1.0 1.7 1 0 0 1 1 1 0 Transposase Mito_fiss_reg PF05308.11 AIO00706.1 - 0.11 12.6 7.3 0.023 14.8 3.2 2.0 2 0 0 2 2 2 0 Mitochondrial fission regulator Con-6 PF10346.9 AIO00706.1 - 0.3 11.1 0.0 0.3 11.1 0.0 4.0 6 0 0 6 6 6 0 Conidiation protein 6 ORF6C PF10552.9 AIO00706.1 - 0.68 10.0 5.1 3.2 7.9 1.9 2.6 2 0 0 2 2 2 0 ORF6C domain ABC_membrane PF00664.23 AIO00707.1 - 1.1e-27 97.3 11.6 1.6e-27 96.9 11.6 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 AIO00707.1 - 2.3e-24 86.5 0.0 3.8e-24 85.8 0.0 1.4 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 AIO00707.1 - 0.00069 19.1 0.0 0.085 12.3 0.0 2.3 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 AIO00707.1 - 0.0039 16.9 0.3 0.044 13.5 0.0 2.2 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_21 PF13304.6 AIO00707.1 - 0.0071 16.2 0.0 0.31 10.8 0.0 2.2 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system T2SSE PF00437.20 AIO00707.1 - 0.021 13.9 0.0 0.04 13.0 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein MMR_HSR1 PF01926.23 AIO00707.1 - 0.079 13.0 0.0 0.17 12.0 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase DUF87 PF01935.17 AIO00707.1 - 0.14 12.2 0.1 0.26 11.4 0.1 1.4 1 0 0 1 1 1 0 Helicase HerA, central domain TrwB_AAD_bind PF10412.9 AIO00707.1 - 0.16 10.8 0.0 0.27 10.1 0.0 1.2 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain AAA_24 PF13479.6 AIO00707.1 - 0.17 11.6 0.0 0.35 10.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain LapA_dom PF06305.11 AIO00707.1 - 0.86 9.5 6.1 25 4.8 0.0 2.9 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain ABC_membrane PF00664.23 AIO00708.1 - 2e-23 83.4 9.2 2.7e-23 83.0 9.2 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region SE PF08491.10 AIO00708.1 - 0.12 11.4 0.4 0.22 10.5 0.4 1.3 1 0 0 1 1 1 0 Squalene epoxidase CAP_GLY PF01302.25 AIO00708.1 - 0.16 12.0 1.2 0.26 11.3 0.4 1.7 2 0 0 2 2 2 0 CAP-Gly domain LapA_dom PF06305.11 AIO00708.1 - 0.27 11.1 0.0 0.27 11.1 0.0 2.8 3 0 0 3 3 3 0 Lipopolysaccharide assembly protein A domain ABC_membrane PF00664.23 AIO00709.1 - 3.1e-27 95.9 7.3 5.3e-27 95.2 7.3 1.4 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 AIO00709.1 - 1.4e-24 87.2 0.0 3.8e-24 85.7 0.0 1.7 2 0 0 2 2 2 1 ABC transporter SMC_N PF02463.19 AIO00709.1 - 0.00087 18.8 0.2 0.12 11.7 0.0 2.1 1 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 AIO00709.1 - 0.0073 16.1 0.0 0.3 10.8 0.0 2.2 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system T2SSE PF00437.20 AIO00709.1 - 0.019 14.1 0.0 0.041 13.0 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_29 PF13555.6 AIO00709.1 - 0.02 14.6 0.0 0.044 13.5 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 AIO00709.1 - 0.078 13.1 0.0 0.17 12.0 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase DUF87 PF01935.17 AIO00709.1 - 0.15 12.1 0.1 0.26 11.4 0.1 1.3 1 0 0 1 1 1 0 Helicase HerA, central domain TrwB_AAD_bind PF10412.9 AIO00709.1 - 0.16 10.8 0.0 0.27 10.1 0.0 1.2 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain AAA_24 PF13479.6 AIO00709.1 - 0.2 11.4 0.0 0.35 10.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain ABC_membrane PF00664.23 AIO00710.1 - 3.3e-17 63.0 4.7 5.2e-17 62.4 4.7 1.3 1 0 0 1 1 1 1 ABC transporter transmembrane region CAP_GLY PF01302.25 AIO00710.1 - 0.11 12.5 1.2 0.21 11.7 0.4 1.8 2 0 0 2 2 2 0 CAP-Gly domain CAP_GLY PF01302.25 AIO00711.1 - 0.0064 16.5 0.8 0.034 14.2 0.4 2.1 2 0 0 2 2 2 1 CAP-Gly domain PP2C PF00481.21 AIO00714.1 - 3.3e-33 115.4 0.0 1e-28 100.7 0.1 2.4 2 0 0 2 2 2 2 Protein phosphatase 2C zf-UBP_var PF17807.1 AIO00714.1 - 0.27 11.0 2.3 0.61 9.9 2.3 1.5 1 0 0 1 1 1 0 Variant UBP zinc finger zf-UBP PF02148.19 AIO00714.1 - 0.28 11.6 10.2 0.58 10.5 10.2 1.5 1 0 0 1 1 1 0 Zn-finger in ubiquitin-hydrolases and other protein CSD PF00313.22 AIO00716.1 - 5.4e-10 39.0 0.1 7.6e-07 28.9 0.0 2.5 2 0 0 2 2 2 2 'Cold-shock' DNA-binding domain DUF4530 PF15039.6 AIO00716.1 - 0.16 12.1 0.0 0.34 11.1 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4530) CSD PF00313.22 AIO00717.1 - 0.00031 20.5 0.0 2 8.3 0.0 3.5 2 1 1 3 3 3 2 'Cold-shock' DNA-binding domain RINGv PF12906.7 AIO00717.1 - 0.18 11.9 0.0 0.34 11.1 0.0 1.4 1 0 0 1 1 1 0 RING-variant domain DUF2175 PF09943.9 AIO00717.1 - 0.24 11.7 0.0 0.42 10.9 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2175) DUF5527 PF17665.1 AIO00718.1 - 0.055 13.0 0.7 0.84 9.2 0.0 2.5 1 1 1 2 2 2 0 Family of unknown function (DUF5527) DUF4549 PF15082.6 AIO00718.1 - 0.79 9.5 5.9 0.29 10.9 0.3 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4549) SPRY PF00622.28 AIO00719.1 - 1.3e-05 25.3 0.0 3.1e-05 24.1 0.0 1.7 1 1 0 1 1 1 1 SPRY domain HAP1_N PF04849.13 AIO00719.1 - 0.00068 18.9 18.5 0.00068 18.9 18.5 3.8 2 2 2 4 4 4 1 HAP1 N-terminal conserved region Neuralized PF07177.12 AIO00719.1 - 0.016 15.2 0.0 0.035 14.1 0.0 1.6 1 0 0 1 1 1 0 Neuralized DUF1388 PF07142.12 AIO00719.1 - 0.14 12.2 2.3 0.51 10.3 2.3 2.0 1 0 0 1 1 1 0 Repeat of unknown function (DUF1388) zf-LSD1 PF06943.12 AIO00722.1 - 1.4e-10 40.8 7.3 1.4e-10 40.8 7.3 2.4 2 0 0 2 2 2 1 LSD1 zinc finger zinc-ribbons_6 PF07191.12 AIO00722.1 - 0.15 12.1 10.5 0.71 9.9 7.3 2.1 2 0 0 2 2 2 0 zinc-ribbons DZR PF12773.7 AIO00722.1 - 0.16 12.0 14.9 12 6.0 10.9 2.3 1 1 1 2 2 2 0 Double zinc ribbon Tmemb_55A PF09788.9 AIO00722.1 - 0.61 9.1 13.4 3.9 6.5 13.3 1.9 1 1 0 1 1 1 0 Transmembrane protein 55A zinc_ribbon_4 PF13717.6 AIO00722.1 - 1 9.3 0.0 1 9.3 0.0 3.9 3 1 1 4 4 3 0 zinc-ribbon domain zinc_ribbon_9 PF14369.6 AIO00722.1 - 3.3 8.0 16.4 3.1 8.1 1.8 2.9 1 1 2 3 3 3 0 zinc-ribbon OrfB_Zn_ribbon PF07282.11 AIO00722.1 - 3.4 7.7 10.0 3 7.8 2.2 2.4 1 1 2 3 3 3 0 Putative transposase DNA-binding domain HypA PF01155.19 AIO00722.1 - 6.6 6.8 11.3 2.1 8.4 0.7 2.1 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Sirohm_synth_M PF14824.6 AIO00723.1 - 0.033 13.6 0.0 0.073 12.5 0.0 1.5 1 0 0 1 1 1 0 Sirohaem biosynthesis protein central ABC_tran PF00005.27 AIO00726.1 - 5.9e-45 153.1 0.0 5.2e-27 95.0 0.0 2.6 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 AIO00726.1 - 8.4e-42 143.7 18.4 4.9e-21 75.6 4.1 2.3 2 0 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.19 AIO00726.1 - 1.3e-09 37.8 0.0 0.025 14.0 0.0 4.1 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 AIO00726.1 - 6.7e-08 32.7 0.0 0.0094 15.8 0.0 3.6 4 0 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system T2SSE PF00437.20 AIO00726.1 - 1.3e-06 27.7 0.0 0.04 13.0 0.0 2.3 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_29 PF13555.6 AIO00726.1 - 1.6e-06 27.7 0.2 0.096 12.4 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain FtsK_SpoIIIE PF01580.18 AIO00726.1 - 1.9e-05 24.1 0.2 0.05 13.0 0.0 2.6 2 0 0 2 2 2 2 FtsK/SpoIIIE family AAA_16 PF13191.6 AIO00726.1 - 3.6e-05 24.2 0.1 0.14 12.5 0.0 3.0 2 0 0 2 2 2 2 AAA ATPase domain MMR_HSR1 PF01926.23 AIO00726.1 - 0.00012 22.1 0.1 0.077 13.1 0.0 2.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_22 PF13401.6 AIO00726.1 - 0.00016 21.9 1.3 0.2 11.9 0.1 3.1 3 0 0 3 3 2 2 AAA domain AAA_23 PF13476.6 AIO00726.1 - 0.00071 20.1 0.0 0.98 9.9 0.0 2.2 2 0 0 2 2 2 2 AAA domain TrwB_AAD_bind PF10412.9 AIO00726.1 - 0.0036 16.3 0.2 2.3 7.1 0.0 2.2 2 0 0 2 2 2 2 Type IV secretion-system coupling protein DNA-binding domain RsgA_GTPase PF03193.16 AIO00726.1 - 0.0042 17.0 0.3 1.2 9.0 0.0 2.4 2 0 0 2 2 2 1 RsgA GTPase AAA_25 PF13481.6 AIO00726.1 - 0.0059 16.2 0.2 4 7.0 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 AIO00726.1 - 0.008 15.9 0.2 5.9 6.6 0.0 2.7 2 0 0 2 2 2 1 AAA domain ATP-synt_ab PF00006.25 AIO00726.1 - 0.0094 15.6 0.1 0.4 10.3 0.0 2.4 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain DUF87 PF01935.17 AIO00726.1 - 0.011 15.9 5.6 0.24 11.5 0.2 2.2 2 0 0 2 2 2 0 Helicase HerA, central domain NACHT PF05729.12 AIO00726.1 - 0.038 13.9 1.2 4.2 7.3 0.1 2.5 2 0 0 2 2 2 0 NACHT domain MeaB PF03308.16 AIO00726.1 - 0.046 12.7 1.8 4.8 6.1 0.1 2.3 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_33 PF13671.6 AIO00726.1 - 0.093 12.9 0.9 9 6.4 0.1 2.8 2 0 0 2 2 2 0 AAA domain Ploopntkinase3 PF18751.1 AIO00726.1 - 0.095 12.6 0.1 4.1 7.3 0.0 2.7 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 Pox_A32 PF04665.12 AIO00726.1 - 0.13 11.7 0.8 7.4 5.9 0.1 2.4 2 0 0 2 2 2 0 Poxvirus A32 protein AAA_5 PF07728.14 AIO00726.1 - 0.14 12.2 0.1 9.9 6.2 0.0 2.6 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) cobW PF02492.19 AIO00726.1 - 0.14 11.7 2.9 7.1 6.2 0.3 2.5 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain DUF2075 PF09848.9 AIO00726.1 - 0.25 10.5 0.6 2 7.6 0.0 2.1 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) Dynamin_N PF00350.23 AIO00726.1 - 0.27 11.3 2.8 5.4 7.0 0.3 2.3 2 0 0 2 2 2 0 Dynamin family AAA_19 PF13245.6 AIO00726.1 - 0.75 10.1 4.3 38 4.6 0.0 4.1 5 0 0 5 5 4 0 AAA domain LRR_8 PF13855.6 AIO00728.1 - 1.3e-11 44.1 0.0 5.9e-05 22.7 0.0 3.2 1 1 2 3 3 3 3 Leucine rich repeat LRR_4 PF12799.7 AIO00728.1 - 0.00019 21.7 0.0 0.014 15.8 0.0 3.2 2 1 0 3 3 3 1 Leucine Rich repeats (2 copies) LRRNT_2 PF08263.12 AIO00728.1 - 0.018 15.3 0.2 0.018 15.3 0.2 2.9 3 0 0 3 3 3 0 Leucine rich repeat N-terminal domain DUF4148 PF13663.6 AIO00728.1 - 2.9 8.1 6.3 1.9 8.8 2.6 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4148) LRR_8 PF13855.6 AIO00729.1 - 7.9e-05 22.3 0.5 0.0024 17.6 0.1 2.4 1 1 0 2 2 2 1 Leucine rich repeat Mucin PF01456.17 AIO00729.1 - 0.0006 19.8 36.8 0.0006 19.8 36.8 2.1 2 0 0 2 2 2 1 Mucin-like glycoprotein LRR_4 PF12799.7 AIO00729.1 - 0.0017 18.7 0.5 2 9.0 0.0 3.3 3 0 0 3 3 3 1 Leucine Rich repeats (2 copies) LRRNT_2 PF08263.12 AIO00729.1 - 0.045 14.1 0.0 0.045 14.1 0.0 2.8 3 0 0 3 3 3 0 Leucine rich repeat N-terminal domain LRR_8 PF13855.6 AIO00730.1 - 3.4e-05 23.5 0.0 0.2 11.4 0.4 3.1 1 1 3 4 4 4 4 Leucine rich repeat LRR_4 PF12799.7 AIO00730.1 - 0.034 14.6 0.4 14 6.3 0.8 3.8 3 1 0 3 3 3 0 Leucine Rich repeats (2 copies) LRR_4 PF12799.7 AIO00732.1 - 8e-12 45.2 3.8 15 6.1 0.0 9.7 8 1 2 10 10 10 5 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 AIO00732.1 - 1.6e-07 30.8 7.0 0.51 10.5 0.2 9.9 11 0 0 11 11 11 2 Leucine Rich repeat HEAT_2 PF13646.6 AIO00732.1 - 0.066 13.6 0.1 0.21 12.0 0.1 1.9 1 0 0 1 1 1 0 HEAT repeats Acyl-CoA_dh_2 PF08028.11 AIO00733.1 - 0.13 12.6 9.2 0.046 14.0 0.8 3.1 3 0 0 3 3 3 0 Acyl-CoA dehydrogenase, C-terminal domain Y_phosphatase3 PF13350.6 AIO00736.1 - 0.18 11.7 0.1 0.29 11.1 0.1 1.2 1 0 0 1 1 1 0 Tyrosine phosphatase family Pkinase PF00069.25 AIO00737.1 - 5.7e-40 137.4 0.0 4.2e-28 98.5 0.0 2.5 3 0 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 AIO00737.1 - 2.6e-20 72.8 0.0 1.2e-18 67.4 0.0 2.7 2 1 0 2 2 2 1 Protein tyrosine kinase PH_3 PF14593.6 AIO00737.1 - 0.00025 21.1 0.0 0.00065 19.8 0.0 1.6 1 0 0 1 1 1 1 PH domain Kinase-like PF14531.6 AIO00737.1 - 0.087 12.1 0.0 0.15 11.4 0.0 1.2 1 0 0 1 1 1 0 Kinase-like L51_S25_CI-B8 PF05047.16 AIO00739.1 - 1e-08 35.0 0.1 3.3e-08 33.3 0.0 2.0 2 0 0 2 2 2 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain LysR_substrate PF03466.20 AIO00739.1 - 0.027 13.8 0.6 0.58 9.5 0.0 2.2 2 0 0 2 2 2 0 LysR substrate binding domain Cmc1 PF08583.10 AIO00742.1 - 0.037 14.0 2.8 0.076 13.0 2.8 1.6 1 1 0 1 1 1 0 Cytochrome c oxidase biogenesis protein Cmc1 like Ribosomal_L36 PF00444.18 AIO00743.1 - 0.00022 21.3 1.6 0.0005 20.2 1.6 1.6 1 0 0 1 1 1 1 Ribosomal protein L36 TP_methylase PF00590.20 AIO00744.1 - 5.6e-21 75.5 0.0 9.9e-21 74.7 0.0 1.4 1 1 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases DUF4434 PF14488.6 AIO00744.1 - 0.023 14.7 0.0 0.047 13.7 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4434) NTPase_I-T PF01931.18 AIO00745.1 - 3.3e-53 179.8 0.1 3.7e-53 179.6 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function DUF84 Thiolase_N PF00108.23 AIO00746.1 - 1.4e-57 195.1 0.7 2.5e-57 194.2 0.7 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 AIO00746.1 - 2.8e-33 114.2 0.0 8.3e-33 112.7 0.0 1.8 1 0 0 1 1 1 1 Thiolase, C-terminal domain SpoVAD PF07451.11 AIO00746.1 - 7.4e-05 21.6 0.1 0.00015 20.6 0.1 1.4 1 0 0 1 1 1 1 Stage V sporulation protein AD (SpoVAD) ketoacyl-synt PF00109.26 AIO00746.1 - 0.00012 21.7 3.7 0.00023 20.8 3.2 1.7 1 1 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain FAE1_CUT1_RppA PF08392.12 AIO00746.1 - 0.0016 17.8 0.1 0.003 16.9 0.1 1.3 1 0 0 1 1 1 1 FAE1/Type III polyketide synthase-like protein ACP_syn_III PF08545.10 AIO00746.1 - 0.2 11.5 2.2 6 6.8 0.8 2.6 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III zf-MYND PF01753.18 AIO00747.1 - 1.6e-10 40.9 9.6 1.6e-10 40.9 9.6 2.1 2 0 0 2 2 2 1 MYND finger zf-C6H2 PF15801.5 AIO00747.1 - 0.00072 19.8 12.3 0.0019 18.4 12.3 1.7 1 0 0 1 1 1 1 zf-MYND-like zinc finger, mRNA-binding zf-Mss51 PF13824.6 AIO00747.1 - 0.34 11.0 5.7 0.94 9.6 5.7 1.7 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 Sld5 PF05916.11 AIO00748.1 - 3.2e-09 37.2 0.0 4.2e-09 36.8 0.0 1.2 1 0 0 1 1 1 1 GINS complex protein GlgS PF08971.11 AIO00750.1 - 0.036 14.1 0.1 0.07 13.2 0.1 1.4 1 0 0 1 1 1 0 Glycogen synthesis protein CLIP1_ZNF PF16641.5 AIO00750.1 - 0.13 12.2 1.5 0.34 10.8 1.5 1.8 1 0 0 1 1 1 0 CLIP1 zinc knuckle DUF1682 PF07946.14 AIO00750.1 - 0.45 9.7 6.9 0.75 8.9 6.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) Anophelin PF10731.9 AIO00751.1 - 0.074 12.9 0.1 1.5 8.7 0.1 2.8 2 0 0 2 2 2 0 Thrombin inhibitor from mosquito UME PF08064.13 AIO00751.1 - 0.18 11.7 0.9 1.1 9.2 0.2 2.8 2 0 0 2 2 2 0 UME (NUC010) domain PPR_3 PF13812.6 AIO00752.1 - 0.072 13.2 0.7 2.3 8.4 0.0 2.8 3 0 0 3 3 3 0 Pentatricopeptide repeat domain PPR_2 PF13041.6 AIO00752.1 - 0.087 13.0 0.5 1.3e+02 2.9 0.0 4.1 5 0 0 5 5 5 0 PPR repeat family CSTF1_dimer PF16699.5 AIO00753.1 - 0.28 11.0 0.6 19 5.1 0.0 3.3 3 0 0 3 3 3 0 Cleavage stimulation factor subunit 1, dimerisation domain Cullin_Nedd8 PF10557.9 AIO00754.1 - 9.9e-14 51.1 0.4 3e-13 49.6 0.3 1.9 2 0 0 2 2 2 1 Cullin protein neddylation domain Cullin PF00888.22 AIO00754.1 - 0.0012 17.6 0.1 0.017 13.7 0.1 2.3 1 1 0 1 1 1 1 Cullin family NAP PF00956.18 AIO00757.1 - 8.6e-76 254.7 0.3 8.6e-76 254.7 0.3 1.8 2 0 0 2 2 2 1 Nucleosome assembly protein (NAP) Cwf_Cwc_15 PF04889.12 AIO00757.1 - 0.022 14.5 18.3 0.047 13.4 7.8 2.5 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein BUD22 PF09073.10 AIO00757.1 - 0.13 11.6 13.9 0.23 10.7 13.9 1.4 1 0 0 1 1 1 0 BUD22 Nop14 PF04147.12 AIO00757.1 - 0.19 9.9 14.5 0.26 9.5 14.5 1.2 1 0 0 1 1 1 0 Nop14-like family CENP-B_dimeris PF09026.10 AIO00757.1 - 0.21 12.0 26.7 1.2 9.6 16.8 2.7 2 0 0 2 2 2 0 Centromere protein B dimerisation domain DNA_pol_phi PF04931.13 AIO00757.1 - 2.3 6.2 22.0 0.19 9.8 12.5 2.1 2 0 0 2 2 2 0 DNA polymerase phi FYDLN_acid PF09538.10 AIO00757.1 - 2.3 8.9 19.0 12 6.6 9.6 3.0 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) RRN3 PF05327.11 AIO00757.1 - 4 5.9 10.3 5.9 5.3 10.3 1.3 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 RNase_H2_suC PF08615.11 AIO00757.1 - 4.7 7.4 11.1 2.5e+02 1.8 11.1 2.3 1 1 0 1 1 1 0 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) PBP1_TM PF14812.6 AIO00757.1 - 5.1 7.5 20.6 5.4 7.5 10.0 2.9 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Pox_Ag35 PF03286.14 AIO00757.1 - 7.4 6.3 19.7 3 7.6 1.7 3.1 3 0 0 3 3 3 0 Pox virus Ag35 surface protein TRAM_LAG1_CLN8 PF03798.16 AIO00758.1 - 7e-41 140.2 19.0 7e-41 140.2 19.0 2.1 2 0 0 2 2 2 1 TLC domain Aa_trans PF01490.18 AIO00760.1 - 3.2e-29 101.9 17.6 4.2e-29 101.5 17.6 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 AIO00760.1 - 1.2e-08 34.4 11.5 2.4e-08 33.4 11.5 1.5 1 0 0 1 1 1 1 Tryptophan/tyrosine permease family Pkinase PF00069.25 AIO00761.1 - 2.1e-16 60.1 0.0 2.9e-16 59.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 AIO00761.1 - 1.4e-13 50.7 0.0 2.3e-09 36.9 0.0 2.2 1 1 1 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 AIO00763.1 - 5.9e-15 55.3 0.0 1.2e-14 54.3 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 AIO00763.1 - 4.1e-12 45.9 0.0 1.7e-11 43.9 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Orf78 PF06024.12 AIO00765.1 - 0.011 16.0 0.0 0.022 15.1 0.0 1.4 1 0 0 1 1 1 0 Orf78 (ac78) Peptidase_M61 PF05299.12 AIO00765.1 - 0.032 14.6 0.0 0.06 13.7 0.0 1.4 1 0 0 1 1 1 0 M61 glycyl aminopeptidase 7tm_1 PF00001.21 AIO00765.1 - 0.093 12.0 0.0 0.093 12.0 0.0 1.1 1 0 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) Glyco_trans_1_4 PF13692.6 AIO00766.1 - 1.2e-10 42.0 0.1 1.1e-09 38.8 0.0 2.6 2 1 1 3 3 3 1 Glycosyl transferases group 1 Glycos_transf_1 PF00534.20 AIO00766.1 - 2.2e-10 40.3 0.0 5e-10 39.2 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 AIO00766.1 - 3.7e-05 24.1 0.0 0.00016 22.0 0.0 2.0 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 AIO00766.1 - 0.00063 19.8 0.1 0.0019 18.2 0.1 1.9 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_transf_90 PF05686.12 AIO00766.1 - 0.0028 16.6 0.1 0.0079 15.2 0.0 1.6 2 0 0 2 2 2 1 Glycosyl transferase family 90 Peptidase_M20 PF01546.28 AIO00767.1 - 6.1e-19 68.5 0.0 8.4e-19 68.1 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 AIO00767.1 - 2.7e-09 36.9 0.0 4.6e-09 36.2 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain ubiquitin PF00240.23 AIO00768.1 - 7.7e-33 112.1 0.3 1e-32 111.7 0.3 1.2 1 0 0 1 1 1 1 Ubiquitin family Ribosomal_L40e PF01020.17 AIO00768.1 - 2.4e-27 94.6 10.7 3.6e-27 94.0 10.7 1.3 1 0 0 1 1 1 1 Ribosomal L40e family Rad60-SLD PF11976.8 AIO00768.1 - 1.9e-16 59.7 0.3 2.7e-16 59.2 0.3 1.2 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 AIO00768.1 - 6.7e-05 23.3 0.1 0.00029 21.2 0.1 1.9 1 1 0 1 1 1 1 Ubiquitin-like domain Ubiquitin_5 PF18037.1 AIO00768.1 - 0.0021 18.4 0.1 0.0042 17.4 0.1 1.5 2 0 0 2 2 2 1 Ubiquitin-like domain TBK1_ULD PF18396.1 AIO00768.1 - 0.0047 16.8 0.0 0.006 16.5 0.0 1.2 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain Rad60-SLD_2 PF13881.6 AIO00768.1 - 0.014 15.5 0.1 0.027 14.6 0.1 1.6 1 1 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_4 PF18036.1 AIO00768.1 - 0.03 14.4 1.1 4.1 7.5 0.2 2.2 2 0 0 2 2 2 0 Ubiquitin-like domain DUF2407 PF10302.9 AIO00768.1 - 0.1 13.2 0.0 0.12 12.9 0.0 1.3 1 1 0 1 1 1 0 DUF2407 ubiquitin-like domain UPF0547 PF10571.9 AIO00768.1 - 3.3 7.9 6.3 5.2 7.2 6.3 1.3 1 0 0 1 1 1 0 Uncharacterised protein family UPF0547 DUF630 PF04783.12 AIO00769.1 - 0.1 12.8 0.4 0.43 10.8 0.4 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF630) RINGv PF12906.7 AIO00770.1 - 5.7e-12 45.6 6.0 5.7e-12 45.6 6.0 2.5 2 0 0 2 2 2 1 RING-variant domain DUF996 PF06195.13 AIO00770.1 - 0.51 10.6 2.2 0.98 9.7 2.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF996) 2TM PF13239.6 AIO00770.1 - 0.61 10.4 2.2 1.7 9.0 2.2 1.7 1 0 0 1 1 1 0 2TM domain Dus PF01207.17 AIO00771.1 - 1.7e-53 181.8 0.3 5.4e-21 75.0 0.0 4.2 4 0 0 4 4 4 4 Dihydrouridine synthase (Dus) DHO_dh PF01180.21 AIO00771.1 - 0.16 11.1 0.0 0.92 8.7 0.0 1.9 2 0 0 2 2 2 0 Dihydroorotate dehydrogenase Thioredoxin_8 PF13905.6 AIO00774.1 - 5.6e-25 87.5 0.1 8.3e-25 87.0 0.1 1.2 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin PF00085.20 AIO00774.1 - 8.2e-10 38.6 0.0 3.4e-08 33.4 0.0 2.1 2 0 0 2 2 2 1 Thioredoxin Redoxin PF08534.10 AIO00774.1 - 2.1e-09 37.3 0.0 2.9e-09 36.8 0.0 1.1 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 AIO00774.1 - 4.5e-07 29.8 0.0 5.7e-07 29.5 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_2 PF13098.6 AIO00774.1 - 1e-05 25.9 0.0 1.6e-05 25.3 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin-like domain TraF PF13728.6 AIO00774.1 - 6.6e-05 22.8 0.0 0.00011 22.2 0.0 1.3 1 0 0 1 1 1 1 F plasmid transfer operon protein Thioredoxin_7 PF13899.6 AIO00774.1 - 0.00084 19.5 0.0 0.0013 18.8 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_9 PF14595.6 AIO00774.1 - 0.0013 18.5 0.0 0.0044 16.8 0.0 1.8 1 1 0 1 1 1 1 Thioredoxin Glutaredoxin PF00462.24 AIO00774.1 - 0.0037 17.4 0.1 0.086 13.1 0.0 2.3 2 0 0 2 2 2 1 Glutaredoxin DUF953 PF06110.11 AIO00774.1 - 0.042 13.5 0.0 1.5 8.4 0.0 2.1 1 1 0 1 1 1 0 Eukaryotic protein of unknown function (DUF953) Herpes_gp2 PF05955.11 AIO00775.1 - 0.14 11.7 1.6 0.14 11.7 0.5 1.5 2 0 0 2 2 2 0 Equine herpesvirus glycoprotein gp2 Peptidase_M8 PF01457.16 AIO00776.1 - 1.5e-127 426.5 0.0 3.4e-127 425.3 0.0 1.4 1 1 0 1 1 1 1 Leishmanolysin SfsA_N PF17746.1 AIO00776.1 - 0.18 12.0 0.0 0.39 10.9 0.0 1.5 1 0 0 1 1 1 0 SfsA N-terminal OB domain CRAL_TRIO PF00650.20 AIO00779.1 - 2.3e-44 150.9 0.0 4e-44 150.1 0.0 1.4 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.6 AIO00779.1 - 0.00044 20.4 0.0 0.0009 19.4 0.0 1.4 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain CRAL_TRIO PF00650.20 AIO00780.1 - 5.4e-38 130.2 0.0 8.8e-38 129.5 0.0 1.4 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.6 AIO00780.1 - 0.0046 17.1 0.0 0.0086 16.2 0.0 1.4 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain CRAL_TRIO_N PF03765.15 AIO00780.1 - 0.011 15.9 0.0 0.026 14.7 0.0 1.7 1 0 0 1 1 1 0 CRAL/TRIO, N-terminal domain CRAL_TRIO PF00650.20 AIO00781.1 - 1.7e-34 118.8 0.0 2.8e-34 118.1 0.0 1.4 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.6 AIO00781.1 - 0.012 15.8 0.0 0.025 14.7 0.0 1.5 1 0 0 1 1 1 0 Divergent CRAL/TRIO domain UBA PF00627.31 AIO00781.1 - 0.038 13.9 0.2 4.5 7.3 0.0 3.2 3 0 0 3 3 3 0 UBA/TS-N domain CorA PF01544.18 AIO00782.1 - 1.3e-07 31.2 0.3 4e-05 23.1 0.2 2.1 2 0 0 2 2 2 2 CorA-like Mg2+ transporter protein SR-25 PF10500.9 AIO00782.1 - 4.2 6.9 13.7 8.1 6.0 13.7 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein tRNA_lig_CPD PF08302.11 AIO00786.1 - 2.3e-08 33.8 0.0 1e-07 31.7 0.0 2.0 2 0 0 2 2 2 1 Fungal tRNA ligase phosphodiesterase domain ABC_tran PF00005.27 AIO00786.1 - 0.06 13.9 0.0 0.12 12.8 0.0 1.5 1 0 0 1 1 1 0 ABC transporter AAA_15 PF13175.6 AIO00786.1 - 0.12 12.1 0.0 0.18 11.4 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain tRNA_lig_kinase PF08303.11 AIO00786.1 - 0.22 11.6 0.0 0.62 10.1 0.0 1.8 1 1 0 1 1 1 0 tRNA ligase kinase domain Aldo_ket_red PF00248.21 AIO00788.1 - 1e-50 172.6 0.0 2.8e-48 164.6 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family SURF6 PF04935.12 AIO00789.1 - 0.17 11.6 1.6 0.44 10.3 1.6 1.6 1 0 0 1 1 1 0 Surfeit locus protein 6 SDA1 PF05285.12 AIO00789.1 - 1.5 8.1 8.4 3 7.2 8.4 1.4 1 0 0 1 1 1 0 SDA1 DUF1389 PF07146.11 AIO00790.1 - 0.087 12.1 0.1 0.16 11.2 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1389) HEAT_2 PF13646.6 AIO00790.1 - 0.14 12.5 17.8 0.41 11.1 6.5 4.8 4 1 1 5 5 5 0 HEAT repeats Mic1 PF07035.12 AIO00790.1 - 0.16 11.7 4.6 0.29 10.8 0.7 2.8 2 0 0 2 2 2 0 Colon cancer-associated protein Mic1-like SARA PF11409.8 AIO00791.1 - 0.034 14.4 0.2 0.14 12.4 0.2 2.1 1 0 0 1 1 1 0 Smad anchor for receptor activation (SARA) ECH_1 PF00378.20 AIO00796.1 - 8.6e-46 156.3 0.0 1.1e-45 155.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 AIO00796.1 - 2.9e-10 40.2 0.0 4.8e-10 39.4 0.0 1.3 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Peptidase_M1_N PF17900.1 AIO00797.1 - 1.1e-06 29.0 0.0 1.8e-06 28.3 0.0 1.3 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain Peptidase_M1 PF01433.20 AIO00797.1 - 1.8e-06 27.7 0.0 3.1e-06 26.9 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M1 domain DA1-like PF12315.8 AIO00797.1 - 0.0033 16.8 0.0 0.0065 15.9 0.0 1.4 1 0 0 1 1 1 1 Protein DA1 Arf PF00025.21 AIO00799.1 - 7.8e-75 250.1 0.2 8.9e-75 249.9 0.2 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 AIO00799.1 - 4.4e-15 56.0 0.1 6e-15 55.5 0.1 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 AIO00799.1 - 3.6e-14 52.7 0.0 4.4e-14 52.4 0.0 1.0 1 0 0 1 1 1 1 Ras family SRPRB PF09439.10 AIO00799.1 - 4e-14 52.5 0.0 4.9e-14 52.2 0.0 1.0 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 AIO00799.1 - 5.4e-12 45.5 0.4 3.2e-08 33.1 0.1 2.4 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.12 AIO00799.1 - 1.3e-07 31.2 0.0 1.6e-07 30.9 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 AIO00799.1 - 1.9e-05 24.7 0.0 3.1e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.18 AIO00799.1 - 0.0017 17.7 0.0 0.0019 17.5 0.0 1.2 1 0 0 1 1 1 1 6-phosphofructo-2-kinase AAA_33 PF13671.6 AIO00799.1 - 0.089 12.9 0.1 0.12 12.6 0.1 1.4 1 1 0 1 1 1 0 AAA domain PEMT PF04191.13 AIO00800.1 - 4.1e-29 101.1 1.2 4.1e-29 101.1 1.2 1.9 2 1 0 2 2 2 1 Phospholipid methyltransferase S1-P1_nuclease PF02265.16 AIO00801.1 - 1.5e-65 221.5 0.1 1.8e-65 221.2 0.1 1.1 1 0 0 1 1 1 1 S1/P1 Nuclease DUF4711 PF15829.5 AIO00801.1 - 0.092 12.7 0.0 0.13 12.2 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4711) SNF2_N PF00176.23 AIO00802.1 - 0.08 11.6 0.1 0.31 9.7 0.1 1.8 1 1 0 1 1 1 0 SNF2 family N-terminal domain ECH_1 PF00378.20 AIO00803.1 - 4.6e-43 147.3 0.0 5.9e-43 147.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 AIO00803.1 - 4.1e-10 39.7 0.0 6.9e-10 38.9 0.0 1.3 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Hydrolase_6 PF13344.6 AIO00804.1 - 6.8e-21 74.3 0.0 1.5e-20 73.2 0.0 1.6 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 AIO00804.1 - 1.2e-15 57.4 0.0 2.8e-15 56.1 0.0 1.6 2 0 0 2 2 2 1 HAD-hyrolase-like PGP_phosphatase PF09419.10 AIO00804.1 - 9e-05 22.2 0.0 0.00026 20.7 0.0 1.7 2 0 0 2 2 2 1 Mitochondrial PGP phosphatase Hydrolase PF00702.26 AIO00804.1 - 0.00089 19.6 0.0 0.29 11.4 0.0 2.6 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 AIO00804.1 - 0.083 13.0 0.0 0.88 9.6 0.0 2.1 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase Mfa2 PF08842.10 AIO00805.1 - 0.16 11.5 0.0 0.37 10.4 0.0 1.5 2 0 0 2 2 2 0 Fimbrillin-A associated anchor proteins Mfa1 and Mfa2 Symplekin_C PF12295.8 AIO00806.1 - 5.6e-13 49.4 4.0 6.1e-12 46.0 0.1 3.3 3 0 0 3 3 3 2 Symplekin tight junction protein C terminal MCU PF04678.13 AIO00808.1 - 0.1 12.7 0.0 0.24 11.5 0.0 1.6 1 0 0 1 1 1 0 Mitochondrial calcium uniporter Cation_efflux PF01545.21 AIO00810.1 - 3.1e-39 134.8 11.0 4.2e-39 134.4 11.0 1.2 1 0 0 1 1 1 1 Cation efflux family Lipase_3 PF01764.25 AIO00817.1 - 4.3e-39 133.6 0.0 9.9e-39 132.4 0.0 1.6 1 1 0 1 1 1 1 Lipase (class 3) DUF2974 PF11187.8 AIO00817.1 - 6e-06 26.0 0.3 6.5e-05 22.6 0.3 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF2974) Hydrolase_4 PF12146.8 AIO00817.1 - 0.0057 15.9 0.0 0.0091 15.3 0.0 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 PGAP1 PF07819.13 AIO00817.1 - 0.029 14.1 0.0 0.39 10.4 0.0 2.1 2 0 0 2 2 2 0 PGAP1-like protein Abhydrolase_6 PF12697.7 AIO00817.1 - 0.043 14.4 0.0 0.059 14.0 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family Esterase PF00756.20 AIO00817.1 - 0.06 13.0 0.1 0.3 10.7 0.0 1.9 2 0 0 2 2 2 0 Putative esterase PRK PF00485.18 AIO00818.1 - 1.2e-41 142.7 0.0 1.4e-41 142.4 0.0 1.1 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family AAA_18 PF13238.6 AIO00818.1 - 4e-09 37.1 0.0 5.7e-09 36.6 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 AIO00818.1 - 0.0013 18.9 0.0 0.0039 17.4 0.0 1.7 1 1 0 1 1 1 1 AAA domain ABC_tran PF00005.27 AIO00818.1 - 0.0052 17.3 0.1 0.0063 17.0 0.1 1.4 1 1 0 1 1 1 1 ABC transporter APS_kinase PF01583.20 AIO00818.1 - 0.008 16.1 0.2 0.77 9.6 0.1 2.3 2 0 0 2 2 2 1 Adenylylsulphate kinase KTI12 PF08433.10 AIO00818.1 - 0.025 14.1 0.1 2.9 7.3 0.0 2.0 2 0 0 2 2 2 0 Chromatin associated protein KTI12 dNK PF01712.19 AIO00818.1 - 0.033 14.0 2.1 0.44 10.4 2.1 2.1 1 1 0 1 1 1 0 Deoxynucleoside kinase RNA_helicase PF00910.22 AIO00818.1 - 0.039 14.4 0.0 0.073 13.5 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_17 PF13207.6 AIO00818.1 - 0.049 14.1 1.6 6.1 7.3 0.2 2.3 2 1 0 2 2 2 0 AAA domain KAP_NTPase PF07693.14 AIO00818.1 - 0.054 12.7 0.0 0.089 12.0 0.0 1.3 1 1 0 1 1 1 0 KAP family P-loop domain NB-ARC PF00931.22 AIO00818.1 - 0.073 12.2 0.1 0.12 11.5 0.1 1.3 1 0 0 1 1 1 0 NB-ARC domain cobW PF02492.19 AIO00818.1 - 0.074 12.6 0.0 0.096 12.3 0.0 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain RsgA_GTPase PF03193.16 AIO00818.1 - 0.16 11.9 0.6 0.43 10.5 0.6 1.6 2 0 0 2 2 2 0 RsgA GTPase AAA_29 PF13555.6 AIO00818.1 - 0.23 11.2 0.4 0.45 10.3 0.4 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain CoaE PF01121.20 AIO00818.1 - 0.35 10.5 1.6 6.6 6.4 0.4 2.1 2 0 0 2 2 2 0 Dephospho-CoA kinase Fer2 PF00111.27 AIO00819.1 - 1.6e-11 44.0 1.2 2.3e-11 43.5 1.2 1.3 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain HECT_2 PF09814.9 AIO00819.1 - 0.011 14.7 0.3 0.012 14.5 0.3 1.1 1 0 0 1 1 1 0 HECT-like Ubiquitin-conjugating enzyme (E2)-binding Fer2 PF00111.27 AIO00820.1 - 9e-09 35.2 2.4 1.3e-08 34.7 2.4 1.2 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer2 PF00111.27 AIO00821.1 - 2.5e-10 40.2 2.0 3.5e-10 39.7 2.0 1.2 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer2 PF00111.27 AIO00822.1 - 1.3e-06 28.2 0.8 2.4e-06 27.4 0.8 1.5 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain EGF_2 PF07974.13 AIO00823.1 - 0.00029 21.1 13.2 0.00029 21.1 13.2 5.8 5 1 0 5 5 5 2 EGF-like domain DUF4684 PF15736.5 AIO00825.1 - 0.12 11.0 0.0 0.15 10.7 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4684) NIPSNAP PF07978.13 AIO00826.1 - 0.011 15.9 0.2 0.038 14.2 0.0 2.0 2 0 0 2 2 2 0 NIPSNAP RNA_polI_A14 PF08203.11 AIO00826.1 - 0.053 14.2 0.2 8.8 7.1 0.0 3.6 3 0 0 3 3 3 0 Yeast RNA polymerase I subunit RPA14 Bep_C_terminal PF17841.1 AIO00828.1 - 0.039 14.2 0.3 0.11 12.7 0.3 1.7 1 0 0 1 1 1 0 BID domain of Bartonella effector protein (Bep) UCR_hinge PF02320.16 AIO00829.1 - 7.3e-18 64.5 3.3 8.1e-18 64.4 3.3 1.0 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase hinge protein TerD PF02342.18 AIO00830.1 - 3.8e-15 55.8 0.1 0.00013 21.5 0.0 3.5 3 0 0 3 3 3 3 TerD domain FXR_C1 PF16096.5 AIO00830.1 - 0.054 13.7 1.7 7.4 6.9 0.2 2.8 2 0 0 2 2 2 0 Fragile X-related 1 protein C-terminal region 2 Calreticulin PF00262.18 AIO00831.1 - 1.6e-77 260.8 16.2 7.7e-55 186.2 5.7 2.1 1 1 1 2 2 2 2 Calreticulin family Laminin_G_2 PF02210.24 AIO00831.1 - 0.0075 16.8 0.2 3.3 8.3 0.1 2.3 2 0 0 2 2 2 2 Laminin G domain Laminin_G_3 PF13385.6 AIO00831.1 - 0.065 13.4 0.0 0.14 12.3 0.0 1.5 1 0 0 1 1 1 0 Concanavalin A-like lectin/glucanases superfamily SL4P PF17618.2 AIO00831.1 - 0.076 13.1 0.3 0.2 11.7 0.3 1.7 1 0 0 1 1 1 0 Uncharacterized Strongylid L4 protein YdfA_immunity PF12127.8 AIO00831.1 - 0.46 9.5 2.0 0.68 8.9 2.0 1.1 1 0 0 1 1 1 0 SigmaW regulon antibacterial RNA_pol_Rpb1_5 PF04998.17 AIO00832.1 - 3.9e-97 324.9 0.2 6.1e-97 324.2 0.2 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_1 PF04997.12 AIO00832.1 - 1.4e-93 313.7 2.1 7.3e-93 311.3 0.0 2.6 3 0 0 3 3 3 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_2 PF00623.20 AIO00832.1 - 9.4e-70 234.1 0.6 2.3e-69 232.8 0.6 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_6 PF04992.14 AIO00832.1 - 5.8e-48 163.3 0.6 1e-47 162.4 0.6 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 6 RNA_pol_Rpb1_3 PF04983.18 AIO00832.1 - 7.5e-40 136.4 0.0 1.8e-39 135.2 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.17 AIO00832.1 - 5.9e-29 100.2 0.1 1.9e-28 98.6 0.1 2.0 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 RNA_pol_Rpb1_7 PF04990.12 AIO00832.1 - 9.4e-23 80.7 0.8 9.4e-23 80.7 0.8 1.9 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 7 PspA_IM30 PF04012.12 AIO00832.1 - 0.035 13.7 1.9 0.078 12.5 1.9 1.5 1 0 0 1 1 1 0 PspA/IM30 family CRCB PF02537.15 AIO00833.1 - 4.7e-14 52.5 10.4 2.3e-13 50.3 1.0 3.0 2 1 1 3 3 3 2 CrcB-like protein, Camphor Resistance (CrcB) Metallophos PF00149.28 AIO00834.1 - 3.1e-37 129.0 0.3 4.1e-37 128.7 0.3 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 AIO00834.1 - 9.5e-08 32.4 0.0 8.4e-07 29.3 0.0 2.3 2 0 0 2 2 2 1 Serine-threonine protein phosphatase N-terminal domain Pyr_redox_2 PF07992.14 AIO00835.1 - 1.6e-48 165.4 0.1 2.2e-48 165.0 0.1 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 AIO00835.1 - 7.6e-18 64.8 0.0 4.6e-17 62.3 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 AIO00835.1 - 2.7e-15 56.7 0.9 6.4e-12 45.9 0.0 3.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 AIO00835.1 - 1.7e-09 37.6 1.2 3.6e-09 36.5 0.1 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 AIO00835.1 - 2.1e-09 37.1 0.9 0.0011 18.3 0.0 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 AIO00835.1 - 3.4e-06 26.9 4.9 0.0096 15.5 0.8 4.0 5 0 0 5 5 5 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 AIO00835.1 - 4.3e-06 26.9 0.8 0.0027 17.9 0.1 2.7 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 AIO00835.1 - 1.1e-05 24.8 0.0 0.00052 19.3 0.0 2.7 2 1 1 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) HI0933_like PF03486.14 AIO00835.1 - 1.3e-05 24.1 7.0 0.0044 15.8 1.0 3.2 3 0 0 3 3 3 2 HI0933-like protein FAD_binding_3 PF01494.19 AIO00835.1 - 2e-05 24.0 3.5 0.0018 17.6 0.4 3.0 2 1 1 3 3 3 1 FAD binding domain GIDA PF01134.22 AIO00835.1 - 2.9e-05 23.3 3.0 0.41 9.7 0.0 3.3 2 1 0 2 2 2 2 Glucose inhibited division protein A Thi4 PF01946.17 AIO00835.1 - 8.7e-05 21.9 1.3 0.012 14.8 0.4 2.4 2 0 0 2 2 2 1 Thi4 family FAD_binding_2 PF00890.24 AIO00835.1 - 0.0001 21.5 9.6 0.00069 18.8 1.9 3.9 2 2 2 4 4 4 1 FAD binding domain ThiF PF00899.21 AIO00835.1 - 0.00022 20.7 0.0 0.00064 19.1 0.0 1.8 2 0 0 2 2 2 1 ThiF family Lycopene_cycl PF05834.12 AIO00835.1 - 0.00068 18.8 1.5 0.21 10.6 0.5 2.5 2 1 0 2 2 2 2 Lycopene cyclase protein NAD_binding_9 PF13454.6 AIO00835.1 - 0.0015 18.5 2.1 4.4 7.3 0.2 3.6 4 0 0 4 4 4 1 FAD-NAD(P)-binding AlaDh_PNT_C PF01262.21 AIO00835.1 - 0.0078 15.5 0.9 3 7.1 0.0 2.3 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain F420_oxidored PF03807.17 AIO00835.1 - 0.011 16.3 0.3 7.8 7.2 0.1 2.9 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent 3HCDH_N PF02737.18 AIO00835.1 - 0.032 14.1 0.6 0.054 13.4 0.0 1.7 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain TrkA_N PF02254.18 AIO00835.1 - 0.062 13.6 0.8 0.37 11.1 0.0 2.4 2 0 0 2 2 2 0 TrkA-N domain Shikimate_DH PF01488.20 AIO00835.1 - 0.099 12.7 0.0 0.28 11.3 0.0 1.7 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Trp_halogenase PF04820.14 AIO00835.1 - 0.52 9.1 2.7 3.8 6.2 0.5 2.2 2 0 0 2 2 2 0 Tryptophan halogenase Pyr_redox_2 PF07992.14 AIO00836.1 - 2.3e-40 138.7 0.1 3.5e-40 138.1 0.1 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 AIO00836.1 - 1.7e-20 73.4 0.1 5.8e-20 71.6 0.1 2.0 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 AIO00836.1 - 1.1e-17 64.4 0.1 1.1e-12 48.3 0.0 3.4 4 0 0 4 4 4 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 AIO00836.1 - 1.4e-10 41.1 0.9 7e-10 38.8 0.0 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 AIO00836.1 - 9.2e-09 35.0 1.2 0.00025 20.4 0.3 2.5 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 AIO00836.1 - 5.2e-08 33.0 1.1 0.00081 19.6 0.4 2.7 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 AIO00836.1 - 2.2e-06 26.6 3.2 1.3e-05 24.1 0.2 3.1 4 0 0 4 4 4 1 HI0933-like protein FAD_binding_2 PF00890.24 AIO00836.1 - 3.5e-06 26.4 0.6 3.5e-06 26.4 0.6 2.2 2 0 0 2 2 2 1 FAD binding domain GIDA PF01134.22 AIO00836.1 - 4.7e-06 25.9 2.8 0.00026 20.2 0.6 3.0 2 1 0 2 2 2 1 Glucose inhibited division protein A DAO PF01266.24 AIO00836.1 - 9.1e-06 25.5 6.3 6.2e-05 22.7 0.2 2.5 2 1 0 2 2 2 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 AIO00836.1 - 1.8e-05 24.0 0.1 0.0015 17.7 0.0 2.4 2 0 0 2 2 2 1 Lycopene cyclase protein Thi4 PF01946.17 AIO00836.1 - 3.3e-05 23.2 3.5 0.0013 18.1 0.2 3.3 3 1 0 3 3 3 1 Thi4 family PALP PF00291.25 AIO00836.1 - 6.7e-05 22.4 0.0 0.00014 21.4 0.0 1.5 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme FAD_binding_3 PF01494.19 AIO00836.1 - 0.00019 20.8 2.4 0.0033 16.7 0.0 2.9 2 1 1 3 3 3 1 FAD binding domain AlaDh_PNT_C PF01262.21 AIO00836.1 - 0.00032 20.1 0.1 0.48 9.7 0.0 2.4 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain ThiF PF00899.21 AIO00836.1 - 0.0033 16.8 0.1 0.0093 15.4 0.1 1.7 1 0 0 1 1 1 1 ThiF family NAD_binding_9 PF13454.6 AIO00836.1 - 0.0085 16.1 0.3 0.42 10.6 0.1 3.2 2 1 0 2 2 2 1 FAD-NAD(P)-binding K_oxygenase PF13434.6 AIO00836.1 - 0.012 14.7 0.0 0.55 9.3 0.0 2.6 2 1 1 3 3 3 0 L-lysine 6-monooxygenase (NADPH-requiring) TrkA_N PF02254.18 AIO00836.1 - 0.25 11.6 1.8 7.6 6.8 0.1 3.1 3 0 0 3 3 3 0 TrkA-N domain SOG2 PF10428.9 AIO00837.1 - 0.81 8.8 18.3 1.6 7.9 18.3 1.4 1 0 0 1 1 1 0 RAM signalling pathway protein RIFIN PF02009.16 AIO00837.1 - 2.9 7.7 7.3 5.3 6.9 7.3 1.3 1 0 0 1 1 1 0 Rifin DUF908 PF06012.12 AIO00837.1 - 9.4 5.5 12.7 20 4.4 12.7 1.6 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) HisKA_3 PF07730.13 AIO00838.1 - 0.014 15.9 1.4 0.1 13.1 1.4 2.6 1 0 0 1 1 1 0 Histidine kinase PPR PF01535.20 AIO00838.1 - 0.15 12.4 0.0 1.4 9.4 0.0 2.6 2 0 0 2 2 2 0 PPR repeat DNA_pol_A_exo1 PF01612.20 AIO00839.1 - 0.00048 19.9 0.0 0.002 17.9 0.0 1.9 2 0 0 2 2 2 1 3'-5' exonuclease MORN PF02493.20 AIO00840.1 - 2.2e-15 55.6 25.2 0.00024 20.8 2.7 5.5 5 0 0 5 5 5 5 MORN repeat Kinesin PF00225.23 AIO00840.1 - 2e-13 50.0 0.0 3.4e-12 45.9 0.0 2.3 1 1 0 1 1 1 1 Kinesin motor domain LOH1CR12 PF10158.9 AIO00840.1 - 0.13 12.3 2.5 0.24 11.4 0.3 2.5 2 0 0 2 2 2 0 Tumour suppressor protein YebO PF13974.6 AIO00840.1 - 0.19 11.9 3.9 1 9.5 3.9 2.3 1 0 0 1 1 1 0 YebO-like protein DUF3774 PF12609.8 AIO00840.1 - 0.95 10.5 5.6 24 6.0 0.8 3.8 2 1 0 2 2 2 0 Wound-induced protein Hemagglutinin PF00509.18 AIO00840.1 - 1.5 7.1 3.0 13 4.1 2.7 2.0 2 0 0 2 2 2 0 Haemagglutinin CAP59_mtransfer PF11735.8 AIO00840.1 - 4.8 6.8 9.7 3.4 7.3 0.8 2.7 2 1 0 2 2 2 0 Cryptococcal mannosyltransferase 1 Bap31 PF05529.12 AIO00841.1 - 0.0011 18.8 3.7 0.0015 18.4 3.7 1.2 1 0 0 1 1 1 1 Bap31/Bap29 transmembrane region DUF4131 PF13567.6 AIO00841.1 - 0.29 10.8 1.2 0.58 9.8 0.5 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4131) RCC1 PF00415.18 AIO00842.1 - 3.6e-25 88.3 17.8 6.6e-12 45.9 0.0 7.3 6 2 0 6 6 6 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 AIO00842.1 - 7e-17 60.8 15.8 0.00056 19.6 1.5 5.0 5 0 0 5 5 5 4 Regulator of chromosome condensation (RCC1) repeat EMP24_GP25L PF01105.24 AIO00843.1 - 2.7e-31 108.9 0.0 3.8e-31 108.4 0.0 1.2 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD COPIIcoated_ERV PF07970.12 AIO00844.1 - 3.4e-64 216.7 0.0 5.7e-64 216.0 0.0 1.4 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.6 AIO00844.1 - 1.7e-25 89.2 0.1 4.3e-25 87.9 0.1 1.7 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) DUF725 PF05267.12 AIO00845.1 - 0.079 12.9 0.2 0.14 12.1 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF725) RRM_1 PF00076.22 AIO00847.1 - 9.3e-12 44.6 0.0 1.9e-11 43.6 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Dysbindin PF04440.16 AIO00848.1 - 3 8.0 11.3 0.56 10.4 1.2 3.1 2 2 2 4 4 4 0 Dysbindin (Dystrobrevin binding protein 1) Arf PF00025.21 AIO00849.1 - 7.1e-78 260.0 0.1 7.7e-78 259.9 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 AIO00849.1 - 2.4e-14 53.2 0.0 2.9e-14 52.9 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 AIO00849.1 - 6.8e-14 51.8 0.4 1.3e-09 37.7 0.0 2.3 1 1 1 2 2 2 2 G-protein alpha subunit Roc PF08477.13 AIO00849.1 - 1.7e-13 50.8 0.0 2.4e-13 50.3 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 AIO00849.1 - 6e-13 48.7 0.0 6.4e-13 48.6 0.0 1.1 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.12 AIO00849.1 - 2.9e-09 36.6 0.0 3.6e-09 36.3 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 AIO00849.1 - 0.00013 22.0 0.0 0.00021 21.3 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.18 AIO00849.1 - 0.0093 15.3 0.0 0.012 15.0 0.0 1.3 1 0 0 1 1 1 1 6-phosphofructo-2-kinase RsgA_GTPase PF03193.16 AIO00849.1 - 0.046 13.6 0.1 0.34 10.8 0.0 2.0 2 0 0 2 2 2 0 RsgA GTPase AAA_33 PF13671.6 AIO00849.1 - 0.1 12.8 0.1 0.18 12.0 0.1 1.6 1 1 0 1 1 1 0 AAA domain DUF1771 PF08590.10 AIO00851.1 - 1.9e-19 69.7 3.1 3.9e-19 68.8 3.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1771) KH_1 PF00013.29 AIO00851.1 - 4.5e-09 36.0 0.5 8.9e-09 35.1 0.5 1.6 1 0 0 1 1 1 1 KH domain Smr PF01713.21 AIO00851.1 - 8.5e-07 29.3 0.0 2.8e-06 27.6 0.0 1.9 1 0 0 1 1 1 1 Smr domain KH_2 PF07650.17 AIO00851.1 - 0.0088 15.9 0.3 0.02 14.7 0.3 1.7 1 0 0 1 1 1 1 KH domain KN17_SH3 PF18131.1 AIO00851.1 - 0.088 12.9 0.1 2.4 8.3 0.0 2.4 2 0 0 2 2 2 0 KN17 SH3-like C-terminal domain Maf1 PF09174.10 AIO00852.1 - 2.8e-26 92.7 0.0 3.7e-26 92.3 0.0 1.1 1 0 0 1 1 1 1 Maf1 regulator Tryp_alpha_amyl PF00234.22 AIO00852.1 - 0.013 15.9 0.0 0.022 15.2 0.0 1.3 1 0 0 1 1 1 0 Protease inhibitor/seed storage/LTP family Pox_RNA_Pol_19 PF05320.12 AIO00853.1 - 0.79 9.7 4.5 0.32 11.0 0.2 2.1 2 0 0 2 2 2 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit Ribosomal_L12 PF00542.19 AIO00855.1 - 1.9e-17 63.3 2.4 3.5e-17 62.5 2.4 1.5 1 0 0 1 1 1 1 Ribosomal protein L7/L12 C-terminal domain T2SSM PF04612.12 AIO00855.1 - 0.026 14.6 0.0 0.055 13.5 0.0 1.6 1 1 0 1 1 1 0 Type II secretion system (T2SS), protein M Pkinase PF00069.25 AIO00856.1 - 7.2e-58 196.0 0.0 1.6e-57 194.9 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 AIO00856.1 - 5.1e-28 98.1 0.0 1.1e-27 97.0 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase RIO1 PF01163.22 AIO00856.1 - 0.005 16.5 0.2 0.019 14.6 0.2 2.0 1 1 0 1 1 1 1 RIO1 family Pox_ser-thr_kin PF05445.11 AIO00856.1 - 0.09 11.7 0.1 0.13 11.2 0.1 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase L71 PF02448.15 AIO00856.1 - 0.19 12.2 0.1 0.55 10.7 0.1 1.7 1 0 0 1 1 1 0 L71 family Peptidase_S80 PF07230.11 AIO00857.1 - 0.16 10.2 0.0 0.2 9.9 0.0 1.1 1 0 0 1 1 1 0 Bacteriophage T4-like capsid assembly protein (Gp20) Aldo_ket_red PF00248.21 AIO00858.1 - 8.1e-57 192.7 0.0 1.7e-55 188.3 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family Clathrin PF00637.20 AIO00859.1 - 2.1e-09 37.4 2.4 5.9e-08 32.7 0.5 2.8 2 0 0 2 2 2 1 Region in Clathrin and VPS zf-C3H2C3 PF17122.5 AIO00859.1 - 0.018 15.0 12.7 0.049 13.7 12.7 1.8 1 0 0 1 1 1 0 Zinc-finger RNA_pol_Rpb1_1 PF04997.12 AIO00859.1 - 0.084 12.2 0.4 0.15 11.4 0.4 1.3 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 1 zf-ANAPC11 PF12861.7 AIO00859.1 - 0.1 12.7 2.6 0.31 11.1 2.6 1.8 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Vps39_2 PF10367.9 AIO00859.1 - 0.4 11.2 9.8 0.39 11.2 5.4 2.4 2 0 0 2 2 2 0 Vacuolar sorting protein 39 domain 2 zf-RING_UBOX PF13445.6 AIO00859.1 - 0.45 10.6 11.0 0.78 9.8 5.6 3.0 2 0 0 2 2 2 0 RING-type zinc-finger zf-rbx1 PF12678.7 AIO00859.1 - 0.6 10.4 8.0 1.9 8.9 8.0 1.8 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 AIO00859.1 - 1.2 9.0 16.6 0.16 11.9 10.5 2.6 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 AIO00859.1 - 4.2 7.4 16.6 1.4 8.9 11.3 2.5 2 0 0 2 2 2 0 zinc-RING finger domain zf-RING_2 PF13639.6 AIO00859.1 - 4.9 7.6 13.3 2.3 8.6 9.9 2.3 2 0 0 2 2 2 0 Ring finger domain Nup54 PF13874.6 AIO00860.1 - 3.8e-21 75.7 0.4 3.8e-21 75.7 0.4 1.7 2 0 0 2 2 2 1 Nucleoporin complex subunit 54 Nup54_C PF18437.1 AIO00860.1 - 0.011 15.6 0.9 0.011 15.6 0.9 2.1 2 0 0 2 2 2 0 Nup54 C-terminal interacting domain RIIa PF02197.17 AIO00861.1 - 0.073 12.7 0.1 0.11 12.2 0.1 1.3 1 0 0 1 1 1 0 Regulatory subunit of type II PKA R-subunit DUF4588 PF15251.6 AIO00862.1 - 0.0059 16.4 1.0 0.0076 16.1 0.1 1.5 2 0 0 2 2 2 1 Domain of unknown function (DUF4588) Inositol_P PF00459.25 AIO00863.1 - 3e-17 63.0 0.0 2.1e-16 60.2 0.0 2.3 1 1 0 1 1 1 1 Inositol monophosphatase family SQS_PSY PF00494.19 AIO00865.1 - 5.8e-46 157.1 0.1 9.3e-46 156.4 0.1 1.3 1 0 0 1 1 1 1 Squalene/phytoene synthase NUDIX PF00293.28 AIO00866.1 - 1.2e-15 57.7 0.0 2.5e-15 56.7 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain zf-NADH-PPase PF09297.11 AIO00866.1 - 1.2e-07 31.3 4.0 2.1e-07 30.4 4.0 1.5 1 0 0 1 1 1 1 NADH pyrophosphatase zinc ribbon domain DZR PF12773.7 AIO00866.1 - 0.0014 18.6 1.0 0.0028 17.7 1.0 1.4 1 0 0 1 1 1 1 Double zinc ribbon HypA PF01155.19 AIO00866.1 - 0.019 15.0 1.1 0.15 12.1 0.4 2.2 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA RecR PF02132.15 AIO00866.1 - 0.029 13.9 0.2 0.054 13.1 0.2 1.4 1 0 0 1 1 1 0 RecR protein NUDIX-like PF09296.11 AIO00866.1 - 0.081 13.6 0.0 0.15 12.7 0.0 1.5 1 0 0 1 1 1 0 NADH pyrophosphatase-like rudimentary NUDIX domain zinc_ribbon_2 PF13240.6 AIO00866.1 - 0.2 11.4 3.7 0.51 10.1 0.6 2.3 2 0 0 2 2 2 0 zinc-ribbon domain zf-ribbon_3 PF13248.6 AIO00866.1 - 0.36 10.3 2.0 0.94 9.0 0.2 2.2 2 0 0 2 2 2 0 zinc-ribbon domain UPF0547 PF10571.9 AIO00866.1 - 2.1 8.5 5.3 26 5.0 1.4 2.3 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 Pkinase PF00069.25 AIO00867.1 - 1.5e-62 211.4 0.0 2e-62 211.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 AIO00867.1 - 3.7e-43 147.7 0.0 5.5e-43 147.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 AIO00867.1 - 5.1e-08 32.6 0.0 1.6e-06 27.7 0.0 2.2 2 0 0 2 2 2 1 Kinase-like PH PF00169.29 AIO00867.1 - 1.3e-05 25.7 0.0 3.6e-05 24.2 0.0 1.8 2 0 0 2 2 2 1 PH domain Haspin_kinase PF12330.8 AIO00867.1 - 0.0066 15.4 0.0 0.009 15.0 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 AIO00867.1 - 0.13 11.6 0.3 0.56 9.5 0.1 1.9 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family PH_9 PF15410.6 AIO00867.1 - 0.18 12.2 0.1 0.47 10.8 0.1 1.7 1 1 0 1 1 1 0 Pleckstrin homology domain Carboxyl_trans PF01039.22 AIO00868.1 - 7.6e-126 420.6 0.0 1e-125 420.2 0.0 1.2 1 0 0 1 1 1 1 Carboxyl transferase domain CPSase_L_D2 PF02786.17 AIO00868.1 - 1e-51 175.5 0.0 1.8e-51 174.6 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain ACC_central PF08326.12 AIO00868.1 - 2.3e-50 171.6 0.0 5.5e-49 167.1 0.0 2.2 1 1 0 1 1 1 1 Acetyl-CoA carboxylase, central region Biotin_carb_N PF00289.22 AIO00868.1 - 9.9e-28 96.9 0.0 6e-27 94.4 0.0 2.2 2 0 0 2 2 2 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 AIO00868.1 - 4.8e-21 74.9 0.0 3.8e-20 72.0 0.0 2.5 3 0 0 3 3 3 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.22 AIO00868.1 - 3e-07 30.2 0.0 7.5e-07 28.9 0.0 1.7 1 0 0 1 1 1 1 Biotin-requiring enzyme Dala_Dala_lig_C PF07478.13 AIO00868.1 - 0.00015 21.3 0.0 0.00037 20.1 0.0 1.6 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 AIO00868.1 - 0.0027 17.3 0.0 0.0082 15.7 0.0 1.7 1 1 0 1 1 1 1 ATP-grasp domain ATP-grasp_3 PF02655.14 AIO00868.1 - 0.059 13.4 0.0 0.14 12.2 0.0 1.6 1 0 0 1 1 1 0 ATP-grasp domain SMK-1 PF04802.15 AIO00869.1 - 2.3e-08 34.1 0.0 3.5e-08 33.5 0.0 1.3 1 0 0 1 1 1 1 Component of IIS longevity pathway SMK-1 3-PAP PF12578.8 AIO00869.1 - 0.08 12.7 0.1 0.2 11.4 0.1 1.6 1 0 0 1 1 1 0 Myotubularin-associated protein FAM184 PF15665.5 AIO00870.1 - 0.0032 17.3 5.9 0.0032 17.3 5.9 9.8 7 2 3 10 10 10 3 Family with sequence similarity 184, A and B ASL_C PF08328.11 AIO00871.1 - 0.025 14.7 4.4 0.048 13.7 1.4 2.5 2 1 0 2 2 2 0 Adenylosuccinate lyase C-terminal Bacillus_HBL PF05791.11 AIO00871.1 - 0.079 12.8 0.0 0.19 11.6 0.0 1.8 1 1 0 1 1 1 0 Bacillus haemolytic enterotoxin (HBL) Mei5 PF10376.9 AIO00871.1 - 0.13 12.1 4.1 0.23 11.3 4.1 1.4 1 0 0 1 1 1 0 Double-strand recombination repair protein Syntaxin-6_N PF09177.11 AIO00871.1 - 0.42 11.2 5.6 0.82 10.3 3.1 2.7 1 1 1 2 2 2 0 Syntaxin 6, N-terminal Hydantoinase_B PF02538.14 AIO00871.1 - 0.45 8.9 3.2 0.63 8.4 3.2 1.2 1 0 0 1 1 1 0 Hydantoinase B/oxoprolinase PIN_8 PF18476.1 AIO00871.1 - 0.45 10.3 10.9 0.17 11.7 7.5 1.9 2 1 1 3 3 3 0 PIN like domain DUF883 PF05957.13 AIO00871.1 - 2.5 8.8 23.2 0.81 10.3 8.2 3.7 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF883) Spc7 PF08317.11 AIO00871.1 - 2.9 6.7 16.9 18 4.1 16.9 2.0 1 1 0 1 1 1 0 Spc7 kinetochore protein BCAS2 PF05700.11 AIO00871.1 - 3.5 7.3 17.7 9 5.9 16.6 1.9 1 1 1 2 2 2 0 Breast carcinoma amplified sequence 2 (BCAS2) DUF724 PF05266.14 AIO00871.1 - 3.7 7.3 9.5 0.92 9.3 5.6 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF724) RE_AccI PF09545.10 AIO00874.1 - 0.023 13.7 0.0 0.03 13.3 0.0 1.2 1 0 0 1 1 1 0 AccI restriction endonuclease IRK PF01007.20 AIO00874.1 - 0.058 13.2 0.9 0.092 12.6 0.9 1.3 1 0 0 1 1 1 0 Inward rectifier potassium channel transmembrane domain Phg_2220_C PF09524.10 AIO00874.1 - 0.12 12.4 2.3 2.1 8.5 0.1 2.3 1 1 1 2 2 2 0 Conserved phage C-terminus (Phg_2220_C) Vma12 PF11712.8 AIO00874.1 - 0.68 10.0 2.7 0.76 9.8 0.7 1.9 1 1 1 2 2 2 0 Endoplasmic reticulum-based factor for assembly of V-ATPase Cyclase PF04199.13 AIO00875.1 - 2.9e-16 59.9 0.0 4.2e-16 59.4 0.0 1.3 1 0 0 1 1 1 1 Putative cyclase Zip PF02535.22 AIO00876.1 - 2.5e-42 145.3 9.1 3.4e-42 144.9 9.1 1.2 1 0 0 1 1 1 1 ZIP Zinc transporter Zip PF02535.22 AIO00877.1 - 1.1e-23 84.0 3.4 1.3e-23 83.8 3.4 1.0 1 0 0 1 1 1 1 ZIP Zinc transporter EFG_IV PF03764.18 AIO00877.1 - 0.17 11.7 0.0 0.27 11.0 0.0 1.6 1 0 0 1 1 1 0 Elongation factor G, domain IV BTB_2 PF02214.22 AIO00878.1 - 0.00023 21.4 0.0 0.00073 19.8 0.0 1.8 1 1 0 1 1 1 1 BTB/POZ domain SPRY PF00622.28 AIO00878.1 - 0.04 14.0 0.0 0.15 12.2 0.0 1.9 1 1 0 1 1 1 0 SPRY domain Peptidase_M16 PF00675.20 AIO00879.1 - 1.9e-32 112.3 0.0 4e-32 111.3 0.0 1.6 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_M PF16187.5 AIO00879.1 - 1.3e-30 106.7 0.0 1.3e-27 96.9 0.0 2.6 3 0 0 3 3 3 2 Middle or third domain of peptidase_M16 Peptidase_M16_C PF05193.21 AIO00879.1 - 2.5e-14 53.7 0.0 3e-09 37.1 0.0 2.7 2 0 0 2 2 2 2 Peptidase M16 inactive domain Nop14 PF04147.12 AIO00879.1 - 0.076 11.2 2.1 0.055 11.7 0.7 1.4 2 0 0 2 2 2 0 Nop14-like family Sigma70_ner PF04546.13 AIO00879.1 - 0.12 12.2 3.7 0.75 9.6 3.6 2.1 2 0 0 2 2 2 0 Sigma-70, non-essential region CDC45 PF02724.14 AIO00879.1 - 0.89 7.8 3.2 1.4 7.1 3.2 1.2 1 0 0 1 1 1 0 CDC45-like protein DnaJ PF00226.31 AIO00880.1 - 1.2e-16 60.5 0.0 2e-16 59.9 0.0 1.3 1 0 0 1 1 1 1 DnaJ domain Autophagy_act_C PF03987.15 AIO00881.1 - 0.013 16.1 0.0 0.03 14.9 0.0 1.7 1 1 0 1 1 1 0 Autophagocytosis associated protein, active-site domain DUF2935 PF11155.8 AIO00882.1 - 0.35 11.2 4.5 10 6.5 4.5 3.3 1 1 0 1 1 1 0 Domain of unknown function (DUF2935) PEMT PF04191.13 AIO00883.1 - 1.4e-53 179.8 10.2 6.4e-30 103.7 0.8 2.9 2 0 0 2 2 2 2 Phospholipid methyltransferase Phage_NinH PF06322.11 AIO00883.1 - 0.13 12.2 0.1 0.24 11.3 0.1 1.4 1 0 0 1 1 1 0 Phage NinH protein CPSase_L_D2 PF02786.17 AIO00884.1 - 1.1e-61 208.1 0.0 1.9e-61 207.3 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.22 AIO00884.1 - 1.1e-43 148.2 0.1 3e-43 146.8 0.0 1.8 2 0 0 2 2 1 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 AIO00884.1 - 3.6e-34 117.1 0.0 7.3e-34 116.1 0.0 1.5 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.22 AIO00884.1 - 5.5e-14 51.8 0.3 1.2e-13 50.7 0.3 1.6 1 0 0 1 1 1 1 Biotin-requiring enzyme Dala_Dala_lig_C PF07478.13 AIO00884.1 - 4.9e-11 42.5 0.0 1.2e-10 41.3 0.0 1.6 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 AIO00884.1 - 4.8e-10 39.3 0.1 8.2e-10 38.5 0.1 1.3 1 0 0 1 1 1 1 ATP-grasp domain Biotin_lipoyl_2 PF13533.6 AIO00884.1 - 1.9e-05 24.4 0.1 0.00031 20.5 0.0 2.4 1 1 1 2 2 2 1 Biotin-lipoyl like ATP-grasp_3 PF02655.14 AIO00884.1 - 0.0016 18.5 0.0 0.0033 17.5 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain RimK PF08443.11 AIO00884.1 - 0.046 13.3 0.0 0.44 10.1 0.0 2.1 1 1 0 1 1 1 0 RimK-like ATP-grasp domain HlyD_3 PF13437.6 AIO00884.1 - 0.13 13.0 0.1 15 6.3 0.0 2.9 3 0 0 3 3 3 0 HlyD family secretion protein DUF3983 PF13137.6 AIO00884.1 - 0.16 11.8 0.0 0.4 10.5 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3983) Robl_LC7 PF03259.17 AIO00886.1 - 3e-05 23.7 0.0 4.5e-05 23.2 0.0 1.3 1 1 0 1 1 1 1 Roadblock/LC7 domain Thioredoxin PF00085.20 AIO00887.1 - 0.023 14.7 1.4 0.055 13.5 1.4 1.6 1 0 0 1 1 1 0 Thioredoxin PQQ_3 PF13570.6 AIO00887.1 - 0.036 14.6 5.0 17 6.0 0.0 4.6 4 0 0 4 4 4 0 PQQ-like domain SHE3 PF17078.5 AIO00887.1 - 0.29 10.8 10.1 1.1 8.9 1.2 2.4 2 0 0 2 2 2 0 SWI5-dependent HO expression protein 3 Exonuc_VII_L PF02601.15 AIO00887.1 - 0.42 10.1 14.7 0.11 12.0 2.8 2.6 2 0 0 2 2 2 0 Exonuclease VII, large subunit UPF0184 PF03670.13 AIO00887.1 - 0.54 10.7 2.8 1.9 9.0 2.8 1.9 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0184) Pkinase PF00069.25 AIO00888.1 - 3e-61 207.1 0.0 4e-61 206.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 AIO00888.1 - 1.5e-41 142.4 0.0 2.1e-41 142.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase PH PF00169.29 AIO00888.1 - 8.9e-13 48.7 0.0 1.9e-12 47.6 0.0 1.6 1 0 0 1 1 1 1 PH domain Kinase-like PF14531.6 AIO00888.1 - 4.4e-08 32.8 0.0 7.2e-08 32.1 0.0 1.3 1 0 0 1 1 1 1 Kinase-like PH_9 PF15410.6 AIO00888.1 - 9.7e-08 32.4 0.4 2.6e-06 27.8 0.4 2.5 1 1 0 1 1 1 1 Pleckstrin homology domain Pkinase_fungal PF17667.1 AIO00888.1 - 0.0012 17.7 0.2 0.059 12.1 0.0 2.1 2 0 0 2 2 2 2 Fungal protein kinase PH_11 PF15413.6 AIO00888.1 - 0.29 11.6 2.3 22 5.5 2.3 2.7 1 1 0 1 1 1 0 Pleckstrin homology domain MFS_1 PF07690.16 AIO00889.1 - 6.2e-18 64.8 42.4 9.3e-18 64.3 22.8 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily Nodulin-like PF06813.13 AIO00889.1 - 1.4e-07 31.3 23.0 1.4e-07 31.3 23.0 3.2 2 2 1 3 3 3 1 Nodulin-like DUF3093 PF11292.8 AIO00889.1 - 0.016 15.5 0.9 0.016 15.5 0.9 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3093) TssO PF17561.2 AIO00889.1 - 0.15 12.2 0.1 0.15 12.2 0.1 3.1 3 0 0 3 3 3 0 Type VI secretion system, TssO CENP-T_C PF15511.6 AIO00890.1 - 1e-05 25.6 0.1 1.7e-05 24.9 0.0 1.3 1 1 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold TAF PF02969.17 AIO00890.1 - 0.00056 20.0 0.1 0.00088 19.4 0.1 1.3 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.23 AIO00890.1 - 0.00058 20.1 0.4 0.00081 19.6 0.0 1.4 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.13 AIO00890.1 - 0.0025 17.8 0.0 0.0029 17.6 0.0 1.2 1 0 0 1 1 1 1 Bromodomain associated Histone PF00125.24 AIO00890.1 - 0.0042 17.4 1.7 0.0082 16.5 1.7 1.5 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID-31kDa PF02291.15 AIO00890.1 - 0.063 13.3 0.0 0.083 13.0 0.0 1.2 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit GIT_CC PF16559.5 AIO00892.1 - 0.22 11.4 2.6 6.8 6.6 0.0 3.5 3 0 0 3 3 3 0 GIT coiled-coil Rho guanine nucleotide exchange factor Myotub-related PF06602.14 AIO00892.1 - 0.45 9.4 8.4 0.39 9.6 2.1 2.1 1 1 1 2 2 2 0 Myotubularin-like phosphatase domain Sec34 PF04136.15 AIO00892.1 - 0.55 10.1 10.5 11 5.9 0.1 3.8 4 0 0 4 4 4 0 Sec34-like family TrbM PF07424.11 AIO00892.1 - 0.86 9.5 5.4 0.57 10.1 0.4 2.5 1 1 1 2 2 2 0 TrbM zf-CCCH PF00642.24 AIO00893.1 - 0.0087 16.0 0.3 0.0087 16.0 0.3 2.1 3 0 0 3 3 3 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 AIO00893.1 - 0.019 15.0 0.7 0.041 14.0 0.7 1.6 1 0 0 1 1 1 0 Zinc finger domain zf-CCCH PF00642.24 AIO00894.1 - 0.011 15.6 0.7 0.011 15.6 0.7 1.9 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) WD40 PF00400.32 AIO00895.1 - 1.3e-17 63.9 4.3 0.025 15.4 0.0 6.2 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 AIO00895.1 - 2.9e-05 24.3 0.2 0.58 10.5 0.0 3.6 2 2 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain NifU_N PF01592.16 AIO00895.1 - 0.19 11.9 0.0 1.2 9.3 0.0 2.2 3 0 0 3 3 3 0 NifU-like N terminal domain SNARE PF05739.19 AIO00897.1 - 7.5e-10 38.7 1.3 9.5e-09 35.1 0.0 2.7 3 0 0 3 3 3 1 SNARE domain Syntaxin PF00804.25 AIO00897.1 - 0.0002 21.1 12.2 0.00063 19.5 7.2 2.5 2 1 0 2 2 2 1 Syntaxin DUF2935 PF11155.8 AIO00897.1 - 0.024 15.0 0.0 1.2 9.5 0.0 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF2935) Baculo_PEP_C PF04513.12 AIO00897.1 - 0.048 13.7 5.3 4 7.5 0.2 3.1 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus SF-assemblin PF06705.11 AIO00897.1 - 0.067 12.5 4.2 1.3 8.3 0.8 2.3 1 1 1 2 2 2 0 SF-assemblin/beta giardin DUF4208 PF13907.6 AIO00897.1 - 0.11 12.9 1.3 4.2 7.9 0.2 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4208) DUF16 PF01519.16 AIO00897.1 - 0.79 10.2 8.5 0.36 11.3 0.8 2.9 2 2 1 3 3 3 0 Protein of unknown function DUF16 Sec8_exocyst PF04048.14 AIO00897.1 - 1.6 8.6 7.5 0.65 9.9 0.3 3.0 2 1 0 3 3 3 0 Sec8 exocyst complex component specific domain DUF883 PF05957.13 AIO00897.1 - 6.1 7.5 7.9 0.85 10.3 0.9 2.8 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF883) NMT PF01233.19 AIO00898.1 - 1.5e-66 223.2 0.0 2.8e-66 222.3 0.0 1.5 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain NMT_C PF02799.15 AIO00898.1 - 2.9e-63 213.2 0.0 4.5e-63 212.6 0.0 1.2 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, C-terminal domain TMEM239 PF15841.5 AIO00899.1 - 0.028 14.3 0.4 0.051 13.5 0.4 1.4 1 0 0 1 1 1 0 Transmembrane protein 239 family NIF PF03031.18 AIO00900.1 - 2.8e-26 92.1 0.0 3.5e-26 91.8 0.0 1.1 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Mito_carr PF00153.27 AIO00901.1 - 3e-40 136.0 5.0 1.2e-14 54.0 0.0 4.2 3 1 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 AIO00901.1 - 0.11 11.7 1.5 9.4 5.3 0.2 2.6 2 1 1 3 3 3 0 Gammaproteobacterial serine protease Pkinase PF00069.25 AIO00902.1 - 6e-58 196.3 0.0 7.7e-58 195.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 AIO00902.1 - 4.5e-27 95.0 0.0 6.4e-27 94.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 AIO00902.1 - 9.3e-05 21.4 0.0 0.00015 20.7 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 AIO00902.1 - 0.00035 20.0 0.0 0.00058 19.3 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 AIO00902.1 - 0.0015 17.9 0.0 0.0029 17.0 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 AIO00902.1 - 0.023 13.7 0.0 0.036 13.0 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain FTA2 PF13095.6 AIO00902.1 - 0.17 11.5 0.0 0.26 10.9 0.0 1.2 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 AIO00902.1 - 0.2 11.6 0.0 0.33 10.8 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Arm PF00514.23 AIO00904.1 - 7.7e-40 133.7 24.9 7.7e-08 32.1 0.1 16.7 16 2 1 17 17 17 9 Armadillo/beta-catenin-like repeat Arm_2 PF04826.13 AIO00904.1 - 1.7e-09 37.5 0.6 0.021 14.3 0.0 5.4 4 2 2 6 6 6 2 Armadillo-like Atx10homo_assoc PF09759.9 AIO00904.1 - 8.8e-05 22.5 1.2 1.9 8.6 0.0 6.2 7 0 0 7 7 7 1 Spinocerebellar ataxia type 10 protein domain HEAT PF02985.22 AIO00904.1 - 0.039 14.2 5.8 23 5.6 0.3 6.1 5 1 0 5 5 5 0 HEAT repeat TBCA PF02970.16 AIO00904.1 - 1.1 9.7 5.5 2.5 8.5 5.5 1.5 1 0 0 1 1 1 0 Tubulin binding cofactor A Utp14 PF04615.13 AIO00905.1 - 3.2e-110 369.9 29.0 3.2e-110 369.9 29.0 1.9 1 1 1 2 2 2 1 Utp14 protein LRR_9 PF14580.6 AIO00908.1 - 3.2e-19 69.1 1.1 7.8e-19 67.8 1.1 1.6 1 1 0 1 1 1 1 Leucine-rich repeat GvpG PF05120.12 AIO00908.1 - 0.12 12.4 2.3 0.21 11.6 2.3 1.4 1 0 0 1 1 1 0 Gas vesicle protein G CCDC-167 PF15188.6 AIO00908.1 - 0.14 12.5 5.4 0.24 11.8 2.6 2.2 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 167 LRR_4 PF12799.7 AIO00908.1 - 0.2 12.1 1.0 32 5.1 0.0 3.4 2 2 1 3 3 3 0 Leucine Rich repeats (2 copies) DUF4404 PF14357.6 AIO00908.1 - 5.9 7.6 6.8 7.3 7.3 3.5 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4404) HSP70 PF00012.20 AIO00910.1 - 3.8e-06 25.4 0.1 0.0039 15.5 0.0 2.5 2 0 0 2 2 2 2 Hsp70 protein Filament PF00038.21 AIO00911.1 - 0.073 12.6 14.7 1.1 8.8 14.7 2.7 1 1 0 1 1 1 0 Intermediate filament protein Fib_alpha PF08702.10 AIO00911.1 - 1.2 9.3 8.9 0.86 9.8 0.6 3.5 4 0 0 4 4 4 0 Fibrinogen alpha/beta chain family NPV_P10 PF05531.12 AIO00911.1 - 2.7 8.5 6.9 11 6.6 0.0 4.1 5 0 0 5 5 5 0 Nucleopolyhedrovirus P10 protein Rtt106 PF08512.12 AIO00912.1 - 6e-12 45.8 0.0 1.6e-10 41.2 0.0 2.8 3 0 0 3 3 3 1 Histone chaperone Rttp106-like SSrecog PF03531.14 AIO00912.1 - 3.4e-05 23.7 0.0 0.00022 21.1 0.0 2.5 2 1 0 2 2 2 1 Structure-specific recognition protein (SSRP1) YL1 PF05764.13 AIO00912.1 - 0.012 15.8 34.9 0.016 15.3 34.9 1.2 1 0 0 1 1 1 0 YL1 nuclear protein Nop53 PF07767.11 AIO00912.1 - 0.028 13.8 30.2 0.042 13.2 30.2 1.2 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) CDC45 PF02724.14 AIO00912.1 - 0.048 12.0 31.4 0.069 11.4 31.4 1.1 1 0 0 1 1 1 0 CDC45-like protein EOS1 PF12326.8 AIO00912.1 - 0.21 11.5 3.1 0.37 10.7 3.1 1.3 1 0 0 1 1 1 0 N-glycosylation protein Nop14 PF04147.12 AIO00912.1 - 0.23 9.6 29.1 0.32 9.2 29.1 1.1 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.12 AIO00912.1 - 0.33 10.3 33.4 0.44 9.9 33.4 1.1 1 0 0 1 1 1 0 SDA1 Coilin_N PF15862.5 AIO00912.1 - 0.72 9.7 21.1 8.9 6.1 21.1 2.3 1 1 0 1 1 1 0 Coilin N-terminus Apt1 PF10351.9 AIO00912.1 - 2 7.2 18.5 2.7 6.8 18.5 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain RR_TM4-6 PF06459.12 AIO00912.1 - 2.9 7.7 20.4 5.4 6.8 20.4 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Glypican PF01153.19 AIO00912.1 - 3.5 6.4 12.6 5 5.8 12.6 1.1 1 0 0 1 1 1 0 Glypican RNA_polI_A34 PF08208.11 AIO00912.1 - 3.6 7.6 38.0 7 6.7 38.0 1.4 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 Adhesin_P1 PF03257.13 AIO00913.1 - 8.1 7.0 9.9 0.65 10.6 1.3 2.7 2 0 0 2 2 2 0 Mycoplasma adhesin P1 Dynein_light PF01221.18 AIO00914.1 - 6.5e-41 138.6 0.9 7.2e-41 138.4 0.9 1.0 1 0 0 1 1 1 1 Dynein light chain type 1 Peptidase_C3 PF00548.20 AIO00914.1 - 0.017 15.0 0.0 0.018 15.0 0.0 1.1 1 0 0 1 1 1 0 3C cysteine protease (picornain 3C) Imm48 PF15574.6 AIO00914.1 - 0.063 13.1 0.1 0.084 12.7 0.1 1.1 1 0 0 1 1 1 0 Immunity protein 48 Ectatomin PF06457.11 AIO00914.1 - 0.065 13.1 0.0 0.12 12.4 0.0 1.4 1 0 0 1 1 1 0 Ectatomin LRR_4 PF12799.7 AIO00915.1 - 0.0063 16.9 4.1 2.3 8.8 0.1 3.8 5 0 0 5 5 5 2 Leucine Rich repeats (2 copies) AAA_13 PF13166.6 AIO00915.1 - 0.21 10.2 1.9 0.31 9.6 1.9 1.2 1 0 0 1 1 1 0 AAA domain LRR_8 PF13855.6 AIO00915.1 - 0.23 11.3 2.2 8 6.3 0.1 3.6 4 0 0 4 4 4 0 Leucine rich repeat LRR_6 PF13516.6 AIO00915.1 - 0.29 11.3 1.7 43 4.5 0.1 4.1 4 0 0 4 4 4 0 Leucine Rich repeat AATF-Che1 PF13339.6 AIO00915.1 - 0.77 10.4 4.5 1.7 9.3 2.8 2.4 2 0 0 2 2 2 0 Apoptosis antagonizing transcription factor Atg14 PF10186.9 AIO00915.1 - 1.7 7.7 11.8 3.2 6.7 11.8 1.4 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF4200 PF13863.6 AIO00915.1 - 2.1 8.7 15.1 6.5 7.2 1.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) Spectrin PF00435.21 AIO00915.1 - 3.1 8.3 10.7 2.4 8.7 3.5 2.7 1 1 1 2 2 2 0 Spectrin repeat Pkinase PF00069.25 AIO00917.1 - 3.3e-67 226.6 0.0 5.1e-67 226.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 AIO00917.1 - 1.3e-51 175.3 0.1 2.1e-51 174.7 0.1 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 AIO00917.1 - 2.5e-05 23.7 0.0 6.4e-05 22.4 0.0 1.6 2 0 0 2 2 2 1 Kinase-like RIO1 PF01163.22 AIO00917.1 - 0.011 15.3 0.2 0.03 13.9 0.2 1.6 1 0 0 1 1 1 0 RIO1 family LRR_8 PF13855.6 AIO00920.1 - 1.4e-11 43.9 12.8 1.7e-06 27.7 2.2 5.3 4 1 1 5 5 5 4 Leucine rich repeat LRR_4 PF12799.7 AIO00920.1 - 4.7e-10 39.6 6.6 0.013 15.9 0.1 4.2 3 1 1 4 4 4 3 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 AIO00920.1 - 0.002 17.7 0.4 0.18 11.3 0.0 2.7 2 1 1 3 3 3 1 Leucine-rich repeat LRR_1 PF00560.33 AIO00920.1 - 0.0033 17.7 6.1 20 6.3 0.1 5.5 5 0 0 5 5 5 2 Leucine Rich Repeat LRR_6 PF13516.6 AIO00920.1 - 0.01 15.8 14.1 1.1 9.5 1.1 6.0 7 0 0 7 7 7 0 Leucine Rich repeat TPR_19 PF14559.6 AIO00921.1 - 3.1e-08 34.0 18.4 0.018 15.5 0.5 8.2 9 1 1 10 10 8 2 Tetratricopeptide repeat Clathrin PF00637.20 AIO00921.1 - 1.3e-06 28.3 0.2 1 9.3 0.0 5.2 5 2 0 5 5 5 1 Region in Clathrin and VPS Nic96 PF04097.14 AIO00921.1 - 2.3e-05 23.1 3.0 0.11 10.9 0.0 4.0 2 1 2 4 4 4 1 Nup93/Nic96 Coatomer_WDAD PF04053.14 AIO00921.1 - 4.9e-05 22.6 2.6 0.032 13.3 0.0 3.4 3 1 1 4 4 4 2 Coatomer WD associated region ANAPC4_WD40 PF12894.7 AIO00921.1 - 0.00017 21.8 0.1 0.26 11.6 0.0 3.7 3 0 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain TPR_14 PF13428.6 AIO00921.1 - 0.0005 20.7 29.0 2.8 9.0 2.3 10.2 9 2 1 10 10 9 2 Tetratricopeptide repeat TPR_7 PF13176.6 AIO00921.1 - 0.00055 19.8 20.5 0.37 10.9 0.6 6.9 8 0 0 8 8 7 3 Tetratricopeptide repeat WD40 PF00400.32 AIO00921.1 - 0.00061 20.5 0.1 3.1 8.8 0.0 3.5 2 0 0 2 2 2 2 WD domain, G-beta repeat Nucleoporin_N PF08801.11 AIO00921.1 - 0.017 13.9 0.0 0.036 12.8 0.0 1.4 1 0 0 1 1 1 0 Nup133 N terminal like TPR_2 PF07719.17 AIO00921.1 - 0.063 13.4 26.4 4 7.8 1.6 8.8 8 1 0 8 8 8 0 Tetratricopeptide repeat TPR_1 PF00515.28 AIO00921.1 - 0.074 12.9 16.9 8.3 6.4 0.2 7.0 6 1 0 6 6 6 0 Tetratricopeptide repeat PPR PF01535.20 AIO00921.1 - 0.15 12.4 0.9 1.5e+02 3.0 0.1 5.2 4 1 0 4 4 4 0 PPR repeat MIT PF04212.18 AIO00921.1 - 3.6 7.7 14.5 17 5.6 0.1 5.9 6 1 0 6 6 6 0 MIT (microtubule interacting and transport) domain TPR_8 PF13181.6 AIO00921.1 - 3.7 8.0 14.1 55 4.4 0.2 7.1 9 0 0 9 9 7 0 Tetratricopeptide repeat TPR_16 PF13432.6 AIO00921.1 - 4 8.2 27.2 0.078 13.6 2.6 6.4 7 0 0 7 7 5 0 Tetratricopeptide repeat TPR_12 PF13424.6 AIO00921.1 - 6.4 7.1 26.0 14 6.0 0.4 7.9 9 1 0 9 9 8 0 Tetratricopeptide repeat RPN7 PF10602.9 AIO00921.1 - 8.9 6.0 8.5 7.3 6.3 0.0 4.3 6 0 0 6 6 6 0 26S proteasome subunit RPN7 DUF3774 PF12609.8 AIO00925.1 - 3.2 8.8 12.4 0.25 12.4 4.0 3.4 2 2 1 3 3 3 0 Wound-induced protein RHD3 PF05879.12 AIO00927.1 - 7.6e-109 364.9 0.0 4.1e-95 319.5 0.0 3.2 3 0 0 3 3 3 3 Root hair defective 3 GTP-binding protein (RHD3) Dynamin_N PF00350.23 AIO00927.1 - 3.3e-05 24.0 0.0 6.3e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 Dynamin family AAA_28 PF13521.6 AIO00927.1 - 0.0015 18.8 0.2 0.0066 16.7 0.1 2.2 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.23 AIO00927.1 - 0.008 16.3 0.0 0.019 15.0 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase JAB PF01398.21 AIO00929.1 - 3.5e-25 88.3 0.0 6.3e-24 84.2 0.0 2.2 2 0 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.6 AIO00929.1 - 4.4e-18 65.7 0.9 8.7e-18 64.8 0.4 1.8 2 0 0 2 2 2 1 Maintenance of mitochondrial structure and function ASL_C PF08328.11 AIO00929.1 - 0.03 14.4 0.7 3.5 7.8 0.2 2.4 2 0 0 2 2 2 0 Adenylosuccinate lyase C-terminal DEAD PF00270.29 AIO00930.1 - 1.2e-46 158.7 0.0 2e-46 158.0 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 AIO00930.1 - 1.2e-32 112.5 0.0 3.9e-31 107.7 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ERCC3_RAD25_C PF16203.5 AIO00930.1 - 0.0021 17.3 0.0 0.0031 16.7 0.0 1.2 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase AAA_22 PF13401.6 AIO00930.1 - 0.048 13.9 0.0 0.41 10.9 0.0 2.2 1 1 0 1 1 1 0 AAA domain TPR_2 PF07719.17 AIO00931.1 - 0.00017 21.5 25.7 1.1 9.6 0.0 8.8 9 0 0 9 9 9 4 Tetratricopeptide repeat TPR_19 PF14559.6 AIO00931.1 - 0.0037 17.7 17.9 1.9 9.0 1.0 5.3 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_1 PF00515.28 AIO00931.1 - 0.2 11.6 7.6 5.7 6.9 1.2 5.0 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_12 PF13424.6 AIO00931.1 - 0.53 10.6 26.9 1.9 8.8 0.1 6.7 6 1 0 7 7 7 0 Tetratricopeptide repeat Kinesin PF00225.23 AIO00932.1 - 1.4e-32 113.0 0.0 1.9e-32 112.6 0.0 1.1 1 0 0 1 1 1 1 Kinesin motor domain MORN PF02493.20 AIO00932.1 - 2.6e-15 55.3 34.8 0.00027 20.6 0.0 7.4 7 0 0 7 7 7 5 MORN repeat Microtub_bd PF16796.5 AIO00932.1 - 1.4e-10 41.3 0.0 2.4e-10 40.5 0.0 1.3 1 0 0 1 1 1 1 Microtubule binding Ribosomal_L22 PF00237.19 AIO00933.1 - 1.1e-31 109.0 0.3 1.4e-31 108.8 0.3 1.1 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e DUF1279 PF06916.13 AIO00934.1 - 4e-06 27.3 0.0 5.9e-06 26.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1279) WW PF00397.26 AIO00934.1 - 3.8e-05 23.7 0.8 7.7e-05 22.7 0.8 1.5 1 0 0 1 1 1 1 WW domain Ribosomal_S5_C PF03719.15 AIO00935.1 - 1.5e-24 85.3 0.0 2.4e-24 84.6 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain Ribosomal_S5 PF00333.20 AIO00935.1 - 6.5e-23 80.5 0.8 1.3e-22 79.5 0.8 1.5 1 0 0 1 1 1 1 Ribosomal protein S5, N-terminal domain FoP_duplication PF13865.6 AIO00935.1 - 0.16 12.5 8.2 0.34 11.5 8.2 1.5 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 Aldo_ket_red PF00248.21 AIO00936.1 - 3.1e-57 194.0 0.0 2.3e-55 187.9 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family LRR_6 PF13516.6 AIO00937.1 - 4.7e-07 29.4 20.4 0.18 11.9 0.0 9.5 11 0 0 11 11 11 2 Leucine Rich repeat LRR_4 PF12799.7 AIO00937.1 - 0.0033 17.8 7.9 2 8.9 0.0 6.4 7 1 0 7 7 7 1 Leucine Rich repeats (2 copies) CLN3 PF02487.17 AIO00937.1 - 0.29 10.2 3.5 1.5 7.8 0.0 2.4 3 0 0 3 3 3 0 CLN3 protein CDC45 PF02724.14 AIO00937.1 - 0.39 8.9 14.9 0.75 8.0 14.9 1.4 1 0 0 1 1 1 0 CDC45-like protein RR_TM4-6 PF06459.12 AIO00937.1 - 0.48 10.2 7.5 0.84 9.4 7.5 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 SDA1 PF05285.12 AIO00937.1 - 2.9 7.2 21.6 5.6 6.3 21.6 1.4 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.12 AIO00937.1 - 9.2 4.3 20.7 13 3.8 20.7 1.2 1 0 0 1 1 1 0 Nop14-like family TauE PF01925.19 AIO00938.1 - 8e-20 71.5 24.5 1.5e-13 50.9 0.6 2.5 2 0 0 2 2 2 2 Sulfite exporter TauE/SafE OTT_1508_deam PF14441.6 AIO00939.1 - 0.12 12.4 0.2 0.2 11.7 0.2 1.3 1 0 0 1 1 1 0 OTT_1508-like deaminase Profilin PF00235.19 AIO00940.1 - 6.2e-42 142.9 0.4 7.9e-42 142.5 0.4 1.1 1 0 0 1 1 1 1 Profilin CDC50 PF03381.15 AIO00941.1 - 1.4e-47 162.5 0.0 1.7e-47 162.3 0.0 1.1 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family DUF1708 PF08101.11 AIO00942.1 - 0.011 14.9 0.1 0.026 13.7 0.1 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF1708) Ras PF00071.22 AIO00943.1 - 2.3e-55 186.6 0.1 2.7e-55 186.4 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 AIO00943.1 - 6.7e-35 119.9 0.1 1.1e-34 119.3 0.1 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 AIO00943.1 - 4.3e-14 52.3 0.0 5.1e-14 52.1 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 AIO00943.1 - 3.4e-06 26.7 0.2 4.5e-05 23.1 0.2 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 AIO00943.1 - 2.2e-05 24.5 0.0 5e-05 23.4 0.0 1.7 1 1 1 2 2 2 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 AIO00943.1 - 0.00036 19.9 0.0 0.00045 19.7 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Septin PF00735.18 AIO00943.1 - 0.00062 19.1 0.0 0.00094 18.5 0.0 1.2 1 0 0 1 1 1 1 Septin RsgA_GTPase PF03193.16 AIO00943.1 - 0.00097 19.1 0.0 0.035 14.0 0.0 2.1 2 0 0 2 2 2 1 RsgA GTPase NACHT PF05729.12 AIO00943.1 - 0.0098 15.8 0.0 0.015 15.2 0.0 1.3 1 0 0 1 1 1 1 NACHT domain PduV-EutP PF10662.9 AIO00943.1 - 0.014 15.1 0.2 0.061 13.1 0.1 1.9 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_22 PF13401.6 AIO00943.1 - 0.029 14.7 0.0 0.057 13.7 0.0 1.7 1 1 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 AIO00943.1 - 0.036 14.5 0.0 0.11 12.9 0.0 2.0 1 1 0 1 1 1 0 RNA helicase AAA_16 PF13191.6 AIO00943.1 - 0.041 14.3 0.0 0.05 14.0 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain TniB PF05621.11 AIO00943.1 - 0.11 11.8 0.0 0.18 11.2 0.0 1.2 1 0 0 1 1 1 0 Bacterial TniB protein AAA_7 PF12775.7 AIO00943.1 - 0.12 11.9 0.0 0.2 11.1 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_24 PF13479.6 AIO00943.1 - 0.13 11.9 0.0 0.16 11.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain YwhD PF08741.10 AIO00943.1 - 0.13 11.9 0.0 0.18 11.5 0.0 1.3 1 0 0 1 1 1 0 YwhD family Med11 PF10280.9 AIO00944.1 - 0.022 15.2 0.7 0.038 14.5 0.7 1.4 1 0 0 1 1 1 0 Mediator complex protein Rtf2 PF04641.12 AIO00946.1 - 1.3e-24 87.0 0.7 2.6e-24 86.0 0.7 1.5 1 1 0 1 1 1 1 Rtf2 RING-finger zf-Nse PF11789.8 AIO00946.1 - 0.015 15.1 0.0 0.58 10.0 0.0 2.5 1 1 1 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit zf-NOSIP PF15906.5 AIO00946.1 - 0.036 14.2 0.0 0.082 13.1 0.0 1.6 1 0 0 1 1 1 0 Zinc-finger of nitric oxide synthase-interacting protein Prok-RING_4 PF14447.6 AIO00946.1 - 0.055 13.3 0.9 0.14 12.1 0.9 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-Mss51 PF13824.6 AIO00946.1 - 0.069 13.3 0.9 0.71 10.0 0.4 2.4 2 1 0 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 MTCP1 PF08991.10 AIO00947.1 - 0.0032 17.7 2.5 0.0032 17.7 2.5 2.2 2 1 0 2 2 2 1 Mature-T-Cell Proliferation I type CHCH PF06747.13 AIO00947.1 - 0.032 14.4 8.8 0.81 9.9 0.8 2.5 2 0 0 2 2 2 0 CHCH domain XG_FTase PF03254.13 AIO00947.1 - 0.069 11.8 0.3 0.3 9.7 0.1 1.8 2 0 0 2 2 2 0 Xyloglucan fucosyltransferase Cmc1 PF08583.10 AIO00947.1 - 0.12 12.4 11.2 0.7 10.0 0.2 3.3 2 2 1 3 3 3 0 Cytochrome c oxidase biogenesis protein Cmc1 like Pet191_N PF10203.9 AIO00947.1 - 0.24 11.7 5.8 0.48 10.8 0.4 2.3 2 0 0 2 2 2 0 Cytochrome c oxidase assembly protein PET191 UPF0203 PF05254.12 AIO00947.1 - 0.85 9.9 10.5 6.1 7.2 0.1 3.1 1 1 2 3 3 3 0 Uncharacterised protein family (UPF0203) zf-C3HC4_3 PF13920.6 AIO00948.1 - 2e-05 24.3 17.7 3.4e-05 23.6 17.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) DEAD PF00270.29 AIO00949.1 - 4.7e-33 114.4 0.1 1e-32 113.3 0.1 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 AIO00949.1 - 2.3e-27 95.5 0.0 1.3e-26 93.1 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 AIO00949.1 - 2.7e-05 24.2 0.1 7.4e-05 22.8 0.0 1.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit YL1 PF05764.13 AIO00950.1 - 0.00055 20.1 9.4 0.00055 20.1 9.4 1.7 2 0 0 2 2 2 1 YL1 nuclear protein LRR19-TM PF15176.6 AIO00950.1 - 0.38 10.8 2.4 0.89 9.6 2.4 1.6 1 0 0 1 1 1 0 Leucine-rich repeat family 19 TM domain Nop14 PF04147.12 AIO00950.1 - 1.4 7.0 10.5 2.7 6.1 10.5 1.4 1 0 0 1 1 1 0 Nop14-like family Astro_capsid_p PF12226.8 AIO00950.1 - 2.8 7.0 14.6 5.1 6.1 14.6 1.4 1 0 0 1 1 1 0 Turkey astrovirus capsid protein Spt5_N PF11942.8 AIO00950.1 - 3 8.9 18.0 0.86 10.6 13.9 2.1 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal DnaJ PF00226.31 AIO00951.1 - 2.1e-09 37.4 0.0 5.7e-09 36.0 0.0 1.8 1 0 0 1 1 1 1 DnaJ domain TMCO5 PF14992.6 AIO00951.1 - 8.3 5.9 9.7 7.3 6.1 1.3 2.8 1 1 0 2 2 2 0 TMCO5 family KxDL PF10241.9 AIO00952.1 - 0.0044 17.3 0.8 0.017 15.4 0.8 2.0 1 0 0 1 1 1 1 Uncharacterized conserved protein TRPM_tetra PF16519.5 AIO00952.1 - 0.0077 16.3 0.8 0.3 11.2 0.6 2.8 2 0 0 2 2 2 1 Tetramerisation domain of TRPM Vac_Fusion PF02346.16 AIO00952.1 - 0.054 13.1 0.7 0.39 10.4 0.1 2.5 2 0 0 2 2 2 0 Chordopoxvirus multifunctional envelope protein A27 DUF4219 PF13961.6 AIO00952.1 - 0.14 11.8 0.2 0.31 10.8 0.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4219) WD40 PF00400.32 AIO00953.1 - 2.2e-10 40.9 1.9 0.00074 20.3 0.1 4.6 4 0 0 4 4 4 3 WD domain, G-beta repeat Ge1_WD40 PF16529.5 AIO00953.1 - 0.0052 15.8 0.1 17 4.3 0.0 3.5 2 1 2 4 4 4 3 WD40 region of Ge1, enhancer of mRNA-decapping protein MMS1_N PF10433.9 AIO00953.1 - 0.089 11.4 0.0 0.57 8.7 0.0 2.0 2 0 0 2 2 2 0 Mono-functional DNA-alkylating methyl methanesulfonate N-term ANAPC4_WD40 PF12894.7 AIO00953.1 - 0.14 12.5 0.1 15 6.0 0.0 3.4 2 1 2 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain AMMECR1 PF01871.17 AIO00955.1 - 3.5e-47 160.1 0.0 4e-47 159.9 0.0 1.0 1 0 0 1 1 1 1 AMMECR1 GP68 PF17469.2 AIO00955.1 - 0.14 12.6 0.0 4.5 7.7 0.0 2.2 2 0 0 2 2 2 0 Phage protein Gp68 DSPc PF00782.20 AIO00956.1 - 1.4e-12 47.6 0.0 2.7e-12 46.6 0.0 1.6 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 AIO00956.1 - 6.9e-11 42.2 0.0 1.5e-10 41.0 0.0 1.5 1 0 0 1 1 1 1 Protein-tyrosine phosphatase CDKN3 PF05706.12 AIO00956.1 - 9.2e-06 25.4 0.0 1.8e-05 24.5 0.0 1.4 1 0 0 1 1 1 1 Cyclin-dependent kinase inhibitor 3 (CDKN3) PTPlike_phytase PF14566.6 AIO00956.1 - 0.00022 21.4 0.0 0.00042 20.5 0.0 1.5 1 0 0 1 1 1 1 Inositol hexakisphosphate Y_phosphatase3 PF13350.6 AIO00956.1 - 0.011 15.7 0.0 0.021 14.8 0.0 1.4 1 0 0 1 1 1 0 Tyrosine phosphatase family RhoGAP PF00620.27 AIO00956.1 - 0.014 15.2 0.0 0.026 14.4 0.0 1.4 1 0 0 1 1 1 0 RhoGAP domain AKAP7_NLS PF10469.9 AIO00957.1 - 3.7e-41 141.3 0.0 4.4e-41 141.0 0.0 1.1 1 0 0 1 1 1 1 AKAP7 2'5' RNA ligase-like domain 2_5_RNA_ligase2 PF13563.6 AIO00957.1 - 4.6e-08 33.1 0.0 6.6e-08 32.6 0.0 1.2 1 0 0 1 1 1 1 2'-5' RNA ligase superfamily EF-hand_7 PF13499.6 AIO00958.1 - 2.9e-11 43.6 0.3 0.0006 20.2 0.1 2.7 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_6 PF13405.6 AIO00958.1 - 5.4e-10 38.4 0.5 0.0017 18.1 0.1 3.7 3 1 1 4 4 4 2 EF-hand domain EF-hand_1 PF00036.32 AIO00958.1 - 3e-08 32.6 0.2 0.0052 16.2 0.1 4.0 4 0 0 4 4 4 2 EF hand EF-hand_8 PF13833.6 AIO00958.1 - 1.9e-06 27.6 6.4 0.00044 20.0 0.5 4.1 2 1 3 5 5 5 2 EF-hand domain pair EF-hand_5 PF13202.6 AIO00958.1 - 0.0029 17.1 0.8 0.27 10.8 0.1 3.0 3 0 0 3 3 3 1 EF hand EFhand_Ca_insen PF08726.10 AIO00958.1 - 0.0071 16.4 0.4 0.09 12.9 0.1 2.5 2 2 0 2 2 2 1 Ca2+ insensitive EF hand YdiH PF15930.5 AIO00958.1 - 0.06 13.5 0.0 2.6 8.3 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function Trypsin_2 PF13365.6 AIO00959.1 - 0.00026 21.9 0.0 0.00064 20.6 0.0 1.7 1 1 0 1 1 1 1 Trypsin-like peptidase domain Kinesin PF00225.23 AIO00960.1 - 9.6e-99 330.4 0.1 9.6e-99 330.4 0.1 2.9 4 0 0 4 4 4 1 Kinesin motor domain Microtub_bd PF16796.5 AIO00960.1 - 1.2e-25 90.2 4.6 1.8e-25 89.7 0.0 3.3 3 0 0 3 3 3 1 Microtubule binding Exo_endo_phos_2 PF14529.6 AIO00960.1 - 1.3 8.9 3.7 2.7 7.9 1.3 2.7 2 0 0 2 2 2 0 Endonuclease-reverse transcriptase DUF2244 PF10003.9 AIO00960.1 - 3.1 7.5 7.3 0.17 11.5 0.9 2.2 2 0 0 2 2 2 0 Integral membrane protein (DUF2244) AAA_16 PF13191.6 AIO00960.1 - 3.5 8.0 0.0 3.5 8.0 0.0 4.6 5 1 0 5 5 5 0 AAA ATPase domain S4 PF01479.25 AIO00961.1 - 0.00018 21.2 0.0 0.00032 20.3 0.0 1.5 1 0 0 1 1 1 1 S4 domain UQ_con PF00179.26 AIO00962.1 - 8.4e-35 119.5 0.0 1.4e-34 118.8 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme BRE PF06113.12 AIO00962.1 - 0.087 11.7 0.0 1.7 7.4 0.0 2.1 1 1 1 2 2 2 0 Brain and reproductive organ-expressed protein (BRE) Mut7-C PF01927.16 AIO00963.1 - 3.1e-45 153.9 0.8 5e-45 153.2 0.8 1.3 1 0 0 1 1 1 1 Mut7-C RNAse domain LSM PF01423.22 AIO00964.1 - 1.8e-12 46.8 0.1 2.2e-12 46.5 0.1 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 AIO00964.1 - 0.028 14.6 0.1 0.043 14.0 0.1 1.4 1 1 0 1 1 1 0 Ataxin 2 SM domain Pan3_PK PF18101.1 AIO00965.1 - 6.6e-40 136.3 0.6 9.6e-40 135.8 0.6 1.2 1 0 0 1 1 1 1 Pan3 Pseudokinase domain LRR_4 PF12799.7 AIO00966.1 - 8.1e-15 54.7 7.6 0.00016 22.0 0.5 4.5 4 0 0 4 4 4 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 AIO00966.1 - 4.2e-12 45.7 10.3 2e-08 33.9 2.7 4.7 4 1 0 4 4 4 2 Leucine rich repeat LRR_9 PF14580.6 AIO00966.1 - 0.0036 16.8 0.0 5.5 6.5 0.1 2.8 2 1 1 3 3 3 3 Leucine-rich repeat LRR_6 PF13516.6 AIO00966.1 - 0.016 15.2 2.4 5.5 7.3 0.0 4.1 4 0 0 4 4 4 0 Leucine Rich repeat LRR_1 PF00560.33 AIO00966.1 - 0.12 13.0 3.7 20 6.2 0.2 5.1 4 2 0 4 4 4 0 Leucine Rich Repeat 4PPT_N PF17837.1 AIO00967.1 - 0.0026 17.8 1.2 0.0026 17.8 1.2 2.2 2 0 0 2 2 2 1 4'-phosphopantetheinyl transferase N-terminal domain RRM_1 PF00076.22 AIO00968.1 - 1.6e-07 31.0 1.0 0.0011 18.8 0.1 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 AIO00968.1 - 0.013 15.1 0.0 0.25 11.0 0.0 2.1 1 1 1 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF2967 PF11179.8 AIO00968.1 - 0.016 13.3 3.7 0.025 12.7 3.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2967) RRM_9 PF18444.1 AIO00968.1 - 0.15 11.9 0.1 1.2 9.0 0.0 2.1 2 0 0 2 2 2 0 RNA recognition motif Cyclin_N PF00134.23 AIO00969.1 - 2.9e-08 33.5 1.7 9.3e-08 31.9 0.4 2.0 2 0 0 2 2 2 1 Cyclin, N-terminal domain RIC1 PF07064.13 AIO00970.1 - 4.9e-42 144.1 0.0 8.9e-42 143.2 0.0 1.4 1 0 0 1 1 1 1 RIC1 ANAPC4_WD40 PF12894.7 AIO00970.1 - 0.02 15.2 0.0 0.82 10.0 0.0 3.5 4 0 0 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain Pkinase PF00069.25 AIO00971.1 - 2e-44 152.0 0.0 3.1e-44 151.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 AIO00971.1 - 3e-28 98.8 0.0 5.3e-28 98.0 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 AIO00971.1 - 0.021 14.8 0.0 0.044 13.7 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.14 AIO00971.1 - 0.039 13.3 0.0 0.078 12.3 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.11 AIO00971.1 - 0.087 11.9 0.0 0.16 11.0 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 Pkinase_fungal PF17667.1 AIO00971.1 - 0.13 11.0 0.0 0.25 10.1 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase Pkinase PF00069.25 AIO00974.1 - 5.7e-50 170.1 0.0 9.2e-50 169.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 AIO00974.1 - 1.1e-35 123.1 0.0 2.3e-35 122.1 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase DUF1356 PF07092.12 AIO00974.1 - 0.054 12.7 0.2 7.7 5.7 0.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1356) HemY_N PF07219.13 AIO00974.1 - 0.075 13.2 0.8 2.7 8.2 1.1 2.4 2 0 0 2 2 2 0 HemY protein N-terminus ARL17 PF15840.5 AIO00974.1 - 0.15 12.5 0.2 0.36 11.2 0.2 1.6 1 0 0 1 1 1 0 ADP-ribosylation factor-like protein 17 Cyclin PF08613.11 AIO00975.1 - 1.1e-23 84.3 0.4 1.5e-23 83.9 0.4 1.1 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 AIO00975.1 - 4.7e-10 39.3 0.3 5.9e-10 39.0 0.3 1.1 1 0 0 1 1 1 1 Cyclin, N-terminal domain Ribosomal_S3Ae PF01015.18 AIO00976.1 - 0.22 11.1 0.0 0.36 10.4 0.0 1.3 1 0 0 1 1 1 0 Ribosomal S3Ae family RRM_8 PF11835.8 AIO00977.1 - 1.1e-07 31.9 0.0 2.6e-07 30.8 0.0 1.6 1 0 0 1 1 1 1 RRM-like domain RRM_1 PF00076.22 AIO00977.1 - 0.0082 15.9 0.0 0.083 12.7 0.0 2.2 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.22 AIO00978.1 - 2e-11 43.5 0.0 0.0026 17.5 0.0 4.3 4 1 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_8 PF11835.8 AIO00978.1 - 0.0068 16.6 0.0 0.021 15.0 0.0 1.7 1 1 0 1 1 1 1 RRM-like domain RRM_5 PF13893.6 AIO00978.1 - 0.03 13.9 0.0 4.2 7.0 0.0 2.6 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 AIO00978.1 - 0.074 13.1 0.0 8.6 6.5 0.0 3.0 3 0 0 3 3 3 0 RNA binding motif RRM_occluded PF16842.5 AIO00978.1 - 0.16 11.8 0.0 0.51 10.2 0.0 1.8 2 0 0 2 2 2 0 Occluded RNA-recognition motif Tmemb_55A PF09788.9 AIO00979.1 - 0.0047 16.0 1.3 0.01 14.9 1.3 1.5 1 0 0 1 1 1 1 Transmembrane protein 55A tRNA-synt_2d PF01409.20 AIO00980.1 - 7.6e-80 267.9 0.1 1.1e-79 267.4 0.1 1.2 1 0 0 1 1 1 1 tRNA synthetases class II core domain (F) PheRS_DBD1 PF18552.1 AIO00980.1 - 7.8e-10 38.4 0.1 1.6e-09 37.4 0.1 1.5 1 0 0 1 1 1 1 PheRS DNA binding domain 1 PheRS_DBD3 PF18553.1 AIO00980.1 - 8e-08 32.5 0.2 1.9e-06 28.0 0.2 2.9 3 0 0 3 3 3 1 PheRS DNA binding domain 3 tRNA_synthFbeta PF17759.1 AIO00980.1 - 0.00036 20.0 0.0 0.52 9.7 0.0 2.6 2 0 0 2 2 2 2 Phenylalanyl tRNA synthetase beta chain CLM domain tRNA-synt_2 PF00152.20 AIO00980.1 - 0.0025 17.0 1.9 0.0033 16.6 0.2 2.0 2 1 1 3 3 3 1 tRNA synthetases class II (D, K and N) tRNA-synt_2b PF00587.25 AIO00980.1 - 0.0052 16.8 0.1 0.028 14.4 0.0 2.0 2 0 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) PheRS_DBD2 PF18554.1 AIO00980.1 - 0.054 13.5 0.2 0.11 12.4 0.2 1.6 1 0 0 1 1 1 0 PheRS DNA binding domain 2 Ribosomal_L18A PF01775.17 AIO00981.1 - 3.4e-40 136.9 1.2 4.5e-40 136.5 1.2 1.2 1 0 0 1 1 1 1 Ribosomal proteins 50S-L18Ae/60S-L20/60S-L18A CTP_transf_like PF01467.26 AIO00982.1 - 7.4e-47 159.1 0.0 5.6e-26 91.5 0.0 2.3 2 0 0 2 2 2 2 Cytidylyltransferase-like FAD_syn PF06574.12 AIO00982.1 - 8.8e-06 25.7 0.4 0.094 12.6 0.1 3.5 3 1 0 3 3 3 2 FAD synthetase CoA_binding_3 PF13727.6 AIO00982.1 - 0.094 12.7 0.0 0.16 12.0 0.0 1.3 1 0 0 1 1 1 0 CoA-binding domain Pantoate_ligase PF02569.15 AIO00982.1 - 0.14 11.4 0.2 0.48 9.6 0.0 1.8 2 0 0 2 2 2 0 Pantoate-beta-alanine ligase CENP-F_leu_zip PF10473.9 AIO00983.1 - 0.0017 18.4 0.4 0.0029 17.6 0.4 1.5 1 1 0 1 1 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Abhydrolase_6 PF12697.7 AIO00984.1 - 2.1e-15 57.9 0.0 2.6e-15 57.7 0.0 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 AIO00984.1 - 7.9e-11 41.7 0.1 1.1e-10 41.2 0.1 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 AIO00984.1 - 5.4e-06 26.2 0.0 8.2e-06 25.6 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Ser_hydrolase PF06821.13 AIO00984.1 - 0.0039 17.1 0.0 0.0093 15.8 0.0 1.6 2 0 0 2 2 2 1 Serine hydrolase Lipase_3 PF01764.25 AIO00984.1 - 0.011 15.6 0.0 0.02 14.7 0.0 1.5 1 0 0 1 1 1 0 Lipase (class 3) Abhydrolase_5 PF12695.7 AIO00984.1 - 0.029 14.1 0.0 0.049 13.4 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family Chlorophyllase2 PF12740.7 AIO00984.1 - 0.078 11.9 0.0 0.21 10.4 0.0 1.6 2 0 0 2 2 2 0 Chlorophyllase enzyme Abhydrolase_9 PF10081.9 AIO00984.1 - 0.16 11.0 1.2 0.37 9.8 0.1 1.8 1 1 1 2 2 2 0 Alpha/beta-hydrolase family V_ATPase_I PF01496.19 AIO00985.1 - 1.7e-246 820.1 0.6 2.4e-246 819.6 0.6 1.2 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family DAO PF01266.24 AIO00986.1 - 8e-08 32.2 3.6 2.4e-06 27.4 0.4 3.0 2 1 1 3 3 3 1 FAD dependent oxidoreductase GMC_oxred_N PF00732.19 AIO00986.1 - 2.7e-06 27.0 0.1 0.0029 17.0 0.0 3.0 2 1 0 2 2 2 2 GMC oxidoreductase FAD_binding_2 PF00890.24 AIO00986.1 - 7e-05 22.1 0.7 0.00053 19.2 0.1 2.1 2 0 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.6 AIO00986.1 - 0.00051 20.2 0.1 0.0016 18.6 0.1 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 AIO00986.1 - 0.0024 17.2 0.2 0.0041 16.4 0.2 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 AIO00986.1 - 0.0032 16.4 0.1 0.005 15.7 0.1 1.2 1 0 0 1 1 1 1 Tryptophan halogenase NAD_binding_9 PF13454.6 AIO00986.1 - 0.0061 16.6 0.1 0.013 15.5 0.1 1.5 1 0 0 1 1 1 1 FAD-NAD(P)-binding Lycopene_cycl PF05834.12 AIO00986.1 - 0.0085 15.2 0.2 0.014 14.5 0.2 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein AlaDh_PNT_C PF01262.21 AIO00986.1 - 0.019 14.2 0.6 0.034 13.4 0.0 1.6 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain HI0933_like PF03486.14 AIO00986.1 - 0.037 12.7 0.1 0.051 12.3 0.1 1.1 1 0 0 1 1 1 0 HI0933-like protein GIDA PF01134.22 AIO00986.1 - 0.1 11.6 0.1 0.16 11.0 0.1 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A CLASP_N PF12348.8 AIO00987.1 - 2.6e-13 50.1 0.7 2.6e-13 50.1 0.7 3.1 4 0 0 4 4 4 1 CLASP N terminal Cnd1 PF12717.7 AIO00987.1 - 0.00083 19.4 0.5 0.16 12.0 0.0 3.6 4 0 0 4 4 4 1 non-SMC mitotic condensation complex subunit 1 DUF5446 PF17522.2 AIO00987.1 - 0.11 12.6 0.3 0.3 11.3 0.3 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5446) HEAT PF02985.22 AIO00987.1 - 0.64 10.4 21.9 4.5 7.8 0.0 7.8 8 0 0 8 8 8 0 HEAT repeat SNase PF00565.17 AIO00988.1 - 4.6e-52 175.1 1.9 3.8e-16 59.5 0.0 5.3 5 0 0 5 5 5 5 Staphylococcal nuclease homologue TUDOR PF00567.24 AIO00988.1 - 1.7e-16 60.3 0.0 3.1e-16 59.5 0.0 1.4 1 0 0 1 1 1 1 Tudor domain DUF4537 PF15057.6 AIO00988.1 - 0.0032 17.5 0.0 0.0083 16.1 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4537) Agenet PF05641.12 AIO00988.1 - 0.086 13.3 0.1 0.66 10.5 0.0 2.5 3 0 0 3 3 3 0 Agenet domain UQ_con PF00179.26 AIO00989.1 - 2.9e-40 137.2 0.0 3.9e-40 136.8 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme DUF3630 PF12305.8 AIO00989.1 - 0.096 12.8 0.0 0.25 11.5 0.0 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3630) Peptidase_C2 PF00648.21 AIO00990.1 - 1.6e-06 27.4 0.0 6.1e-06 25.5 0.0 1.8 2 0 0 2 2 2 1 Calpain family cysteine protease RRM_1 PF00076.22 AIO00991.1 - 0.043 13.6 0.0 0.092 12.6 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Vps23_core PF09454.10 AIO00992.1 - 6.8e-17 61.2 0.1 1.7e-16 59.9 0.1 1.7 1 0 0 1 1 1 1 Vps23 core domain MHB PF16525.5 AIO00992.1 - 0.092 13.0 0.1 0.19 12.0 0.1 1.6 1 0 0 1 1 1 0 Haemophore, haem-binding Cpn60_TCP1 PF00118.24 AIO00993.1 - 2.1e-151 504.9 2.0 2.4e-151 504.7 2.0 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Y_phosphatase2 PF03162.13 AIO00994.1 - 4.8e-22 78.3 0.0 8.5e-21 74.2 0.0 2.3 1 1 0 1 1 1 1 Tyrosine phosphatase family Ashwin PF15323.6 AIO00994.1 - 0.031 14.3 1.5 0.044 13.8 1.5 1.2 1 0 0 1 1 1 0 Developmental protein Pkinase PF00069.25 AIO00995.1 - 1.3e-32 113.2 0.2 8.4e-26 90.9 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 AIO00995.1 - 5.2e-17 62.0 0.3 9.7e-17 61.1 0.3 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase FTA2 PF13095.6 AIO00995.1 - 0.0003 20.5 0.0 0.0011 18.7 0.0 1.9 2 0 0 2 2 2 1 Kinetochore Sim4 complex subunit FTA2 Pkinase_fungal PF17667.1 AIO00995.1 - 0.011 14.6 0.0 0.019 13.7 0.0 1.5 1 1 0 1 1 1 0 Fungal protein kinase DUF747 PF05346.11 AIO00995.1 - 0.061 12.8 0.2 0.1 12.1 0.2 1.2 1 0 0 1 1 1 0 Eukaryotic membrane protein family Maf PF02545.14 AIO00996.1 - 7.5e-18 64.9 0.0 9.1e-18 64.7 0.0 1.1 1 0 0 1 1 1 1 Maf-like protein ATP11 PF06644.11 AIO00996.1 - 0.013 15.3 0.1 0.018 14.9 0.1 1.3 1 0 0 1 1 1 0 ATP11 protein HEPN_AbiU2 PF18734.1 AIO00996.1 - 0.093 12.2 0.0 0.14 11.7 0.0 1.2 1 0 0 1 1 1 0 AbiU2 LemA PF04011.12 AIO00997.1 - 0.082 12.8 3.5 2.1 8.2 1.5 2.7 2 0 0 2 2 2 0 LemA family TMF_DNA_bd PF12329.8 AIO00997.1 - 3.9 7.5 20.7 2.4 8.2 1.2 4.9 5 0 0 5 5 5 0 TATA element modulatory factor 1 DNA binding PI3K_P85_iSH2 PF16454.5 AIO00997.1 - 9 5.9 17.8 1.5 8.4 4.1 3.0 2 1 0 2 2 2 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain Metallophos_2 PF12850.7 AIO00998.1 - 1.7e-11 44.6 0.0 1.9e-11 44.4 0.0 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos_3 PF14582.6 AIO00998.1 - 0.18 11.1 0.0 3.2 7.0 0.0 2.0 1 1 0 2 2 2 0 Metallophosphoesterase, calcineurin superfamily WD40 PF00400.32 AIO00999.1 - 4.6e-09 36.8 8.9 0.15 13.0 0.1 5.3 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 AIO00999.1 - 0.00069 19.9 0.1 0.053 13.8 0.0 3.1 3 0 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain PBECR4 PF18813.1 AIO00999.1 - 0.024 14.9 0.1 0.13 12.5 0.0 1.9 2 0 0 2 2 2 0 phage-Barnase-EndoU-ColicinE5/D-RelE like nuclease4 LSM PF01423.22 AIO01000.1 - 3.6e-14 52.2 0.1 4e-14 52.0 0.1 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 AIO01000.1 - 0.00042 20.4 0.1 0.00047 20.2 0.1 1.1 1 0 0 1 1 1 1 Ataxin 2 SM domain HECT PF00632.25 AIO01002.1 - 4.1e-69 233.4 0.0 6e-69 232.9 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) ZZ PF00569.17 AIO01002.1 - 0.00016 21.4 8.1 0.00016 21.4 8.1 2.2 2 0 0 2 2 2 1 Zinc finger, ZZ type Utp14 PF04615.13 AIO01002.1 - 0.061 11.9 0.4 0.1 11.2 0.4 1.2 1 0 0 1 1 1 0 Utp14 protein CRM1_C PF08767.11 AIO01003.1 - 7.9e-61 206.0 0.6 7.9e-61 206.0 0.6 2.9 4 0 0 4 4 4 1 CRM1 C terminal CRM1_repeat_2 PF18784.1 AIO01003.1 - 1.7e-26 91.6 1.2 5.2e-26 90.1 1.2 1.9 1 0 0 1 1 1 1 CRM1 / Exportin repeat 2 Xpo1 PF08389.12 AIO01003.1 - 3.3e-26 92.1 4.8 5.8e-26 91.3 1.2 3.3 3 0 0 3 3 3 1 Exportin 1-like protein CRM1_repeat_3 PF18787.1 AIO01003.1 - 2.2e-23 82.1 3.8 2.5e-23 81.9 1.4 2.5 2 0 0 2 2 2 1 CRM1 / Exportin repeat 3 CRM1_repeat PF18777.1 AIO01003.1 - 1.6e-09 37.1 1.1 5.3e-09 35.5 1.1 2.0 1 0 0 1 1 1 1 Chromosome region maintenance or exportin repeat IBN_N PF03810.19 AIO01003.1 - 1.1e-08 34.9 0.3 9.4e-08 31.9 0.3 2.7 2 0 0 2 2 2 1 Importin-beta N-terminal domain DUF4473 PF14747.6 AIO01003.1 - 0.0039 17.7 0.2 2.7 8.6 0.0 3.1 2 1 0 2 2 2 1 Domain of unknown function (DUF4473) Mito_carr PF00153.27 AIO01004.1 - 6.3e-48 160.7 1.8 2.4e-15 56.2 0.1 3.1 2 1 1 3 3 3 3 Mitochondrial carrier protein DUF4199 PF13858.6 AIO01004.1 - 0.059 13.8 0.5 0.13 12.7 0.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4199) ThrE_2 PF12821.7 AIO01004.1 - 0.06 13.5 1.0 0.15 12.2 1.0 1.6 1 0 0 1 1 1 0 Threonine/Serine exporter, ThrE Mito_carr PF00153.27 AIO01005.1 - 1.7e-48 162.5 1.8 9.9e-16 57.4 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein PPR_2 PF13041.6 AIO01007.1 - 0.011 15.9 0.1 36 4.6 0.0 4.0 3 1 1 4 4 4 0 PPR repeat family ELO PF01151.18 AIO01009.1 - 6e-50 170.1 16.2 8.8e-50 169.6 16.2 1.2 1 0 0 1 1 1 1 GNS1/SUR4 family Ank_4 PF13637.6 AIO01011.1 - 2.5e-08 34.3 0.1 1.3e-07 32.0 0.1 2.2 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 AIO01011.1 - 4e-07 30.5 0.0 1.5e-06 28.7 0.0 2.0 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 AIO01011.1 - 1.5e-06 28.1 0.3 0.012 16.1 0.1 3.2 2 0 0 2 2 2 2 Ankyrin repeat Ank PF00023.30 AIO01011.1 - 2.6e-06 27.6 1.2 0.05 14.1 0.1 2.8 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.6 AIO01011.1 - 6.9e-06 26.2 0.7 2e-05 24.7 0.7 1.8 1 0 0 1 1 1 1 Ankyrin repeats (many copies) T-box_assoc PF16176.5 AIO01012.1 - 0.091 12.8 0.4 2.1 8.4 0.1 2.3 2 0 0 2 2 2 0 T-box transcription factor-associated CSN8_PSD8_EIF3K PF10075.9 AIO01013.1 - 1e-26 93.6 0.0 1.7e-26 92.9 0.0 1.2 1 0 0 1 1 1 1 CSN8/PSMD8/EIF3K family HhH-GPD PF00730.25 AIO01013.1 - 0.16 12.5 0.0 0.4 11.2 0.0 1.7 1 0 0 1 1 1 0 HhH-GPD superfamily base excision DNA repair protein PPR_2 PF13041.6 AIO01014.1 - 2.4e-43 146.1 17.1 9.4e-12 44.9 0.1 12.4 8 3 5 13 13 13 8 PPR repeat family PPR_3 PF13812.6 AIO01014.1 - 1.5e-28 98.6 8.3 2.7e-12 46.6 0.0 9.1 6 2 3 10 10 10 5 Pentatricopeptide repeat domain PPR_long PF17177.4 AIO01014.1 - 9.7e-18 64.3 12.1 6.3e-11 42.0 0.5 5.5 4 1 0 5 5 5 3 Pentacotripeptide-repeat region of PRORP PPR PF01535.20 AIO01014.1 - 1.2e-15 56.6 11.6 3.6e-05 23.7 0.0 9.5 9 0 0 9 9 9 4 PPR repeat PPR_1 PF12854.7 AIO01014.1 - 1.8e-08 34.0 18.7 0.00065 19.3 0.0 9.0 10 0 0 10 10 10 2 PPR repeat COX5A PF02284.16 AIO01014.1 - 1.5e-05 24.9 1.5 0.17 11.9 0.0 3.7 2 1 1 3 3 3 2 Cytochrome c oxidase subunit Va RPM2 PF08579.11 AIO01014.1 - 0.00037 20.9 4.4 4.1 7.8 0.1 5.2 2 2 1 3 3 3 2 Mitochondrial ribonuclease P subunit (RPM2) ECSIT PF06239.11 AIO01014.1 - 0.00052 19.2 1.9 5.8 6.0 0.0 4.9 3 2 2 5 5 5 2 Evolutionarily conserved signalling intermediate in Toll pathway PPP1R35_C PF15503.6 AIO01014.1 - 0.072 12.9 0.1 0.18 11.6 0.1 1.7 1 0 0 1 1 1 0 Protein phosphatase 1 regulatory subunit 35 C-terminus TPR_15 PF13429.6 AIO01014.1 - 0.082 12.1 0.3 0.25 10.5 0.3 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat Histone_HNS PF00816.21 AIO01015.1 - 0.33 11.8 3.1 0.73 10.7 0.3 2.8 2 0 0 2 2 2 0 H-NS histone family PilO PF04350.13 AIO01015.1 - 0.49 10.5 5.2 1 9.5 0.4 2.7 2 0 0 2 2 2 0 Pilus assembly protein, PilO ArfGap PF01412.18 AIO01016.1 - 9.6e-27 93.4 0.1 1.7e-26 92.5 0.1 1.3 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf Apolipoprotein PF01442.18 AIO01016.1 - 0.038 13.9 0.1 0.057 13.3 0.1 1.2 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain TF_Zn_Ribbon PF08271.12 AIO01016.1 - 0.13 11.9 2.1 0.24 11.0 2.1 1.4 1 0 0 1 1 1 0 TFIIB zinc-binding PHTB1_C PF14728.6 AIO01017.1 - 1.4e-102 343.6 0.5 2.2e-102 343.0 0.5 1.2 1 0 0 1 1 1 1 PTHB1 C-terminus PHTB1_N PF14727.6 AIO01017.1 - 1.3e-89 301.5 0.0 1.6e-65 222.1 0.0 2.1 2 0 0 2 2 2 2 PTHB1 N-terminus BBS2_Mid PF14783.6 AIO01017.1 - 0.082 13.0 0.0 0.18 11.8 0.0 1.5 1 0 0 1 1 1 0 Ciliary BBSome complex subunit 2, middle region UCH PF00443.29 AIO01018.1 - 1.8e-33 116.1 0.0 2.7e-33 115.5 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 AIO01018.1 - 3.5e-14 53.1 0.0 8.2e-07 28.9 0.0 2.3 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase Ipi1_N PF12333.8 AIO01018.1 - 0.053 14.1 0.1 0.12 13.0 0.1 1.6 1 0 0 1 1 1 0 Rix1 complex component involved in 60S ribosome maturation CRAL_TRIO PF00650.20 AIO01019.1 - 1.1e-35 122.7 0.0 1.6e-35 122.2 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain GOLD_2 PF13897.6 AIO01019.1 - 0.0003 21.3 0.1 0.11 13.0 0.0 2.3 1 1 1 2 2 2 2 Golgi-dynamics membrane-trafficking UBA_4 PF14555.6 AIO01019.1 - 0.16 11.8 1.2 4.9 7.0 0.4 2.4 2 0 0 2 2 2 0 UBA-like domain TetR_C_11 PF16859.5 AIO01019.1 - 0.16 12.3 0.0 0.36 11.2 0.0 1.5 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain CRAL_TRIO PF00650.20 AIO01020.1 - 6.2e-33 113.8 0.0 8.9e-33 113.3 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.6 AIO01020.1 - 0.00058 20.0 0.0 0.0011 19.1 0.0 1.5 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain CRAL_TRIO_N PF03765.15 AIO01020.1 - 0.024 14.8 0.2 0.051 13.8 0.2 1.6 1 0 0 1 1 1 0 CRAL/TRIO, N-terminal domain CRAL_TRIO PF00650.20 AIO01021.1 - 8.1e-29 100.4 0.0 2e-28 99.1 0.0 1.7 1 1 0 1 1 1 1 CRAL/TRIO domain SHS2_Rpb7-N PF03876.17 AIO01022.1 - 2e-14 53.7 0.0 3.3e-14 53.0 0.0 1.4 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 Pkinase PF00069.25 AIO01023.1 - 7.7e-09 35.3 0.0 1.2e-08 34.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 AIO01023.1 - 3.7e-06 26.4 0.0 5.5e-06 25.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 AIO01023.1 - 0.00013 22.0 0.7 0.00027 20.9 0.0 1.9 2 0 0 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 AIO01023.1 - 0.0045 16.6 0.0 0.0081 15.8 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase Haspin_kinase PF12330.8 AIO01023.1 - 0.012 14.6 0.0 0.021 13.8 0.0 1.4 1 0 0 1 1 1 0 Haspin like kinase domain Pep_deformylase PF01327.21 AIO01024.1 - 2.6e-26 92.1 0.0 4e-26 91.5 0.0 1.2 1 0 0 1 1 1 1 Polypeptide deformylase WLM PF08325.10 AIO01025.1 - 4.5e-32 111.7 0.0 4.1e-30 105.3 0.0 2.4 2 1 0 2 2 2 1 WLM domain DUF45 PF01863.17 AIO01025.1 - 0.0035 17.4 1.2 0.0057 16.7 1.2 1.2 1 0 0 1 1 1 1 Protein of unknown function DUF45 RecR PF02132.15 AIO01025.1 - 0.018 14.6 3.1 0.063 12.9 3.1 1.8 1 0 0 1 1 1 0 RecR protein OrfB_Zn_ribbon PF07282.11 AIO01025.1 - 0.54 10.2 2.5 1.4 8.9 2.5 1.7 1 0 0 1 1 1 0 Putative transposase DNA-binding domain VSG_B PF13206.6 AIO01026.1 - 6.4 5.9 12.1 0.79 8.9 7.9 1.6 2 0 0 2 2 2 0 Trypanosomal VSG domain Peptidase_C97 PF05903.14 AIO01027.1 - 1.2e-18 67.4 0.0 2.3e-18 66.4 0.0 1.4 1 0 0 1 1 1 1 PPPDE putative peptidase domain CPSF_A PF03178.15 AIO01028.1 - 1.6e-64 218.3 0.0 2.6e-64 217.6 0.0 1.3 1 0 0 1 1 1 1 CPSF A subunit region MMS1_N PF10433.9 AIO01028.1 - 9.8e-18 64.0 0.0 1.7e-13 50.0 0.0 3.3 2 1 0 2 2 2 2 Mono-functional DNA-alkylating methyl methanesulfonate N-term LicD PF04991.13 AIO01029.1 - 2.8e-08 34.2 0.0 4.8e-08 33.4 0.0 1.3 1 0 0 1 1 1 1 LicD family SP_C-Propep PF08999.10 AIO01029.1 - 0.015 15.0 0.0 0.035 13.9 0.0 1.5 1 0 0 1 1 1 0 Surfactant protein C, N terminal propeptide mRNA_cap_enzyme PF01331.19 AIO01030.1 - 8.5e-08 32.2 0.0 1.6e-07 31.4 0.0 1.4 1 0 0 1 1 1 1 mRNA capping enzyme, catalytic domain ADK PF00406.22 AIO01030.1 - 1.6e-07 31.5 0.0 1.3e-06 28.6 0.0 2.1 1 1 1 2 2 2 1 Adenylate kinase AAA_17 PF13207.6 AIO01030.1 - 2.4e-07 31.2 0.0 1.7e-06 28.5 0.0 2.2 1 1 0 1 1 1 1 AAA domain mRNA_cap_C PF03919.15 AIO01030.1 - 1.6e-06 28.7 0.0 7e-06 26.6 0.0 2.0 2 0 0 2 2 2 1 mRNA capping enzyme, C-terminal domain AAA_18 PF13238.6 AIO01030.1 - 6.3e-06 26.8 0.0 1.6e-05 25.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 AIO01030.1 - 0.00092 19.4 0.1 0.0061 16.7 0.1 2.1 1 1 0 1 1 1 1 AAA domain Thymidylate_kin PF02223.17 AIO01030.1 - 0.0019 17.9 0.0 0.79 9.4 0.0 2.3 1 1 0 2 2 2 2 Thymidylate kinase AAA_22 PF13401.6 AIO01030.1 - 0.0051 17.1 0.0 0.012 15.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 AIO01030.1 - 0.02 14.2 0.0 0.39 10.0 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin AAA_14 PF13173.6 AIO01030.1 - 0.027 14.5 0.0 0.05 13.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 AIO01030.1 - 0.038 13.7 0.0 0.07 12.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain SRP54 PF00448.22 AIO01030.1 - 0.11 12.1 0.0 0.17 11.5 0.0 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_28 PF13521.6 AIO01030.1 - 0.11 12.7 0.0 0.31 11.3 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 AIO01031.1 - 0.0089 16.6 0.0 0.017 15.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 AIO01031.1 - 0.031 14.4 0.0 0.07 13.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 AIO01031.1 - 0.1 13.0 0.1 0.3 11.5 0.0 1.8 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 AIO01031.1 - 0.14 12.5 0.0 0.32 11.4 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain PAM2 PF07145.15 AIO01031.1 - 0.25 11.1 3.7 0.78 9.6 1.5 2.5 2 0 0 2 2 2 0 Ataxin-2 C-terminal region DUF2730 PF10805.8 AIO01032.1 - 0.23 11.5 0.1 18 5.5 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2730) Uds1 PF15456.6 AIO01032.1 - 0.5 10.5 2.4 12 6.0 2.4 2.1 1 1 0 1 1 1 0 Up-regulated During Septation DEAD PF00270.29 AIO01034.1 - 3.3e-21 75.8 0.1 1.3e-20 73.8 0.1 2.1 1 1 0 1 1 1 1 DEAD/DEAH box helicase Sec63 PF02889.16 AIO01034.1 - 5.4e-18 65.1 0.4 3.3e-15 55.9 0.0 2.7 3 0 0 3 3 3 2 Sec63 Brl domain ResIII PF04851.15 AIO01034.1 - 2.1e-06 27.9 0.0 9.8e-06 25.7 0.0 1.9 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 AIO01034.1 - 3e-06 27.5 0.0 1.8e-05 25.1 0.0 2.2 1 1 0 1 1 1 1 Helicase conserved C-terminal domain T2SSE PF00437.20 AIO01034.1 - 0.013 14.5 0.4 0.063 12.3 0.0 2.2 3 0 0 3 3 3 0 Type II/IV secretion system protein AAA_22 PF13401.6 AIO01034.1 - 0.14 12.4 0.0 14 5.9 0.0 2.7 2 0 0 2 2 2 0 AAA domain Cyclase PF04199.13 AIO01035.1 - 6.5e-10 39.4 0.0 3.6e-09 37.0 0.0 2.0 1 1 0 1 1 1 1 Putative cyclase CDC45 PF02724.14 AIO01037.1 - 1.7 6.8 4.8 2.7 6.2 4.8 1.2 1 0 0 1 1 1 0 CDC45-like protein PI3_PI4_kinase PF00454.27 AIO01040.1 - 5.1e-45 154.2 0.1 8.8e-45 153.5 0.1 1.4 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FATC PF02260.20 AIO01040.1 - 2e-10 40.3 0.7 2e-10 40.3 0.7 2.5 3 0 0 3 3 3 1 FATC domain FAT PF02259.23 AIO01040.1 - 8.1e-09 35.1 0.5 4.3e-06 26.2 0.1 3.4 2 1 0 2 2 2 1 FAT domain UME PF08064.13 AIO01040.1 - 0.13 12.2 0.2 0.97 9.4 0.0 2.7 2 0 0 2 2 2 0 UME (NUC010) domain MIP-T3 PF10243.9 AIO01041.1 - 4.7e-27 94.2 0.3 8.3e-27 93.4 0.0 1.5 2 0 0 2 2 2 1 Microtubule-binding protein MIP-T3 CH-like domain rRNA_processing PF08524.11 AIO01043.1 - 9.3e-11 42.0 32.7 1.3e-09 38.2 32.7 2.1 1 1 0 1 1 1 1 rRNA processing TEX13 PF15186.6 AIO01043.1 - 1.9 8.2 14.8 3.8 7.2 1.1 2.3 1 1 1 2 2 2 0 Testis-expressed sequence 13 protein family DUF4407 PF14362.6 AIO01043.1 - 4.8 6.4 16.6 5.9 6.1 16.6 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) CENP-L PF13092.6 AIO01044.1 - 0.011 16.0 0.0 0.021 15.1 0.0 1.5 1 0 0 1 1 1 0 Kinetochore complex Sim4 subunit Fta1 DUF4228 PF14009.6 AIO01044.1 - 0.044 14.2 0.1 0.22 11.9 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4228) Peptidase_M41 PF01434.18 AIO01045.1 - 5.9e-46 156.7 0.3 5.9e-46 156.7 0.3 1.6 2 0 0 2 2 2 1 Peptidase family M41 AAA PF00004.29 AIO01045.1 - 7.6e-41 139.6 0.0 1.5e-40 138.7 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 AIO01045.1 - 6.5e-05 23.4 0.1 0.00088 19.7 0.1 2.4 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 AIO01045.1 - 0.0021 18.3 0.2 0.029 14.6 0.2 2.6 1 1 0 1 1 1 1 AAA domain TIP49 PF06068.13 AIO01045.1 - 0.0098 15.1 0.1 0.023 13.9 0.0 1.6 1 1 0 1 1 1 1 TIP49 P-loop domain RuvB_N PF05496.12 AIO01045.1 - 0.013 15.3 0.0 0.036 13.8 0.0 1.8 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 AIO01045.1 - 0.019 15.0 0.3 0.11 12.6 0.1 2.3 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.26 AIO01045.1 - 0.039 13.7 0.0 0.21 11.3 0.0 2.2 1 1 0 1 1 1 0 Sigma-54 interaction domain Zeta_toxin PF06414.12 AIO01045.1 - 0.041 13.2 0.0 0.096 12.0 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin IstB_IS21 PF01695.17 AIO01045.1 - 0.065 13.0 0.1 0.15 11.8 0.1 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_lid_3 PF17862.1 AIO01045.1 - 0.079 12.8 0.0 0.25 11.2 0.0 1.8 1 0 0 1 1 1 0 AAA+ lid domain DUF2075 PF09848.9 AIO01045.1 - 0.085 12.1 0.1 0.13 11.5 0.1 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) NACHT PF05729.12 AIO01045.1 - 0.17 11.8 0.1 0.67 9.9 0.1 1.9 2 0 0 2 2 2 0 NACHT domain AAA_2 PF07724.14 AIO01045.1 - 0.18 11.9 0.6 2.3 8.3 0.4 2.6 1 1 1 2 2 2 0 AAA domain (Cdc48 subfamily) AAA_24 PF13479.6 AIO01045.1 - 0.18 11.5 0.1 1 9.0 0.0 2.3 3 0 0 3 3 3 0 AAA domain AAA_7 PF12775.7 AIO01045.1 - 0.21 11.1 0.8 1.8 8.1 0.1 2.5 2 1 0 2 2 2 0 P-loop containing dynein motor region Pex14_N PF04695.13 AIO01045.1 - 5.8 7.5 9.2 1 10.0 4.6 2.2 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region YqaJ PF09588.10 AIO01046.1 - 6.7e-52 175.6 0.0 1.1e-51 174.9 0.0 1.4 1 0 0 1 1 1 1 YqaJ-like viral recombinase domain NUDIX PF00293.28 AIO01048.1 - 3.8e-11 43.1 0.4 3.4e-10 40.1 0.4 2.0 1 1 0 1 1 1 1 NUDIX domain PSP1 PF04468.12 AIO01049.1 - 7e-23 80.7 1.4 1.2e-22 80.0 1.4 1.4 1 0 0 1 1 1 1 PSP1 C-terminal conserved region eIF3_p135 PF12807.7 AIO01050.1 - 3.4e-09 37.0 0.0 6.3e-09 36.1 0.0 1.3 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit 135 CLU PF13236.6 AIO01050.1 - 4.5e-09 36.5 0.0 7.2e-09 35.8 0.0 1.3 1 0 0 1 1 1 1 Clustered mitochondria ArfGap PF01412.18 AIO01051.1 - 1.4e-39 134.8 0.1 2.4e-39 134.0 0.1 1.4 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf PMI_typeI PF01238.21 AIO01052.1 - 6.7e-91 305.3 0.0 7.7e-91 305.1 0.0 1.0 1 0 0 1 1 1 1 Phosphomannose isomerase type I PIF1 PF05970.14 AIO01053.1 - 1.5e-37 129.7 1.1 3e-15 56.3 0.0 4.4 4 0 0 4 4 4 4 PIF1-like helicase AAA_30 PF13604.6 AIO01053.1 - 6.2e-14 52.2 0.0 2.6e-12 46.9 0.0 3.4 3 1 0 3 3 3 1 AAA domain AAA_19 PF13245.6 AIO01053.1 - 2.4e-05 24.7 0.0 0.00036 20.9 0.0 2.7 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.6 AIO01053.1 - 0.0012 19.3 0.1 0.0052 17.2 0.1 2.1 1 0 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.14 AIO01053.1 - 0.0026 17.8 0.2 0.096 12.7 0.1 2.6 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) UvrD_C_2 PF13538.6 AIO01053.1 - 0.0027 17.5 0.0 0.0083 15.9 0.0 1.8 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain NTPase_1 PF03266.15 AIO01053.1 - 0.0033 17.3 0.1 0.71 9.8 0.0 2.3 2 0 0 2 2 2 1 NTPase IstB_IS21 PF01695.17 AIO01053.1 - 0.0048 16.7 1.2 1.4 8.7 0.1 3.2 3 0 0 3 3 3 1 IstB-like ATP binding protein AAA_22 PF13401.6 AIO01053.1 - 0.0084 16.4 0.0 0.79 10.0 0.0 2.6 2 0 0 2 2 2 1 AAA domain Helicase_RecD PF05127.14 AIO01053.1 - 0.014 15.3 0.1 2 8.2 0.1 2.6 2 0 0 2 2 2 0 Helicase DUF87 PF01935.17 AIO01053.1 - 0.018 15.2 0.1 0.042 13.9 0.1 1.6 1 0 0 1 1 1 0 Helicase HerA, central domain Viral_helicase1 PF01443.18 AIO01053.1 - 0.021 14.6 0.2 5.8 6.6 0.0 3.5 3 0 0 3 3 3 0 Viral (Superfamily 1) RNA helicase SH3_13 PF18335.1 AIO01053.1 - 0.023 14.5 0.0 0.054 13.3 0.0 1.6 1 0 0 1 1 1 0 ATP-dependent RecD-like DNA helicase SH3 domain AAA PF00004.29 AIO01053.1 - 0.025 15.0 0.0 0.28 11.6 0.0 2.7 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Herpes_Helicase PF02689.14 AIO01053.1 - 0.029 12.3 0.8 4.3 5.1 0.8 2.3 2 0 0 2 2 2 0 Helicase DUF815 PF05673.13 AIO01053.1 - 0.048 12.8 0.1 0.087 12.0 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) NACHT PF05729.12 AIO01053.1 - 0.053 13.4 0.0 0.12 12.3 0.0 1.6 1 0 0 1 1 1 0 NACHT domain PhoH PF02562.16 AIO01053.1 - 0.084 12.3 0.0 0.17 11.3 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein MeaB PF03308.16 AIO01053.1 - 0.2 10.6 1.0 0.36 9.8 0.2 1.9 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB PIN_11 PF18479.1 AIO01055.1 - 0.016 15.3 0.1 0.63 10.2 0.1 2.3 2 0 0 2 2 2 0 PIN like domain Cucumo_coat PF00760.18 AIO01056.1 - 0.16 11.6 0.1 0.63 9.7 0.0 1.9 2 0 0 2 2 2 0 Cucumovirus coat protein FlgT_N PF16548.5 AIO01058.1 - 0.054 14.1 1.2 0.1 13.2 1.2 1.5 1 0 0 1 1 1 0 Flagellar assembly protein T, N-terminal domain NAD_synthase PF02540.17 AIO01061.1 - 1.6e-32 112.5 0.0 1.9e-32 112.3 0.0 1.1 1 0 0 1 1 1 1 NAD synthase Asn_synthase PF00733.21 AIO01061.1 - 0.19 11.4 0.0 0.31 10.7 0.0 1.3 1 0 0 1 1 1 0 Asparagine synthase PP2C PF00481.21 AIO01063.1 - 5.3e-68 229.4 0.0 7.6e-68 228.9 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C Pex14_N PF04695.13 AIO01063.1 - 0.61 10.7 4.9 0.27 11.9 1.5 2.0 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region SpoU_methylase PF00588.19 AIO01065.1 - 1.3e-11 44.8 0.1 0.015 15.5 0.0 3.9 4 0 0 4 4 4 3 SpoU rRNA Methylase family DNA_pol_E_B PF04042.16 AIO01066.1 - 2.7e-12 46.5 0.1 1.1e-10 41.3 0.0 2.2 2 0 0 2 2 2 2 DNA polymerase alpha/epsilon subunit B Coatomer_E PF04733.14 AIO01067.1 - 3.6e-30 105.4 5.1 1.3e-22 80.5 2.3 2.0 2 0 0 2 2 2 2 Coatomer epsilon subunit TPR_14 PF13428.6 AIO01067.1 - 5.1e-05 23.8 11.1 1.2 10.2 0.0 5.4 3 2 1 5 5 5 2 Tetratricopeptide repeat TPR_2 PF07719.17 AIO01067.1 - 5.6e-05 22.9 4.7 0.72 10.1 0.0 5.8 5 1 1 6 6 6 1 Tetratricopeptide repeat TPR_8 PF13181.6 AIO01067.1 - 0.00035 20.6 1.9 0.11 12.7 0.0 4.8 5 1 1 6 6 6 1 Tetratricopeptide repeat TPR_12 PF13424.6 AIO01067.1 - 0.0048 17.1 10.2 0.041 14.2 3.1 4.9 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_1 PF00515.28 AIO01067.1 - 0.017 14.9 4.9 0.48 10.3 0.0 4.9 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_10 PF13374.6 AIO01067.1 - 0.021 14.7 4.5 6.6 6.7 0.2 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_4 PF07721.14 AIO01067.1 - 0.025 15.2 3.2 2.6 8.9 0.1 4.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_19 PF14559.6 AIO01067.1 - 0.038 14.5 14.5 0.66 10.5 0.9 4.5 3 2 2 5 5 5 0 Tetratricopeptide repeat OstA_2 PF13100.6 AIO01067.1 - 0.045 13.4 0.1 1.1 8.8 0.0 2.4 2 1 0 2 2 2 0 OstA-like protein TPR_16 PF13432.6 AIO01067.1 - 5.6 7.7 19.3 0.23 12.1 3.5 4.3 4 1 0 4 4 4 0 Tetratricopeptide repeat WW PF00397.26 AIO01068.1 - 2.8e-12 46.5 0.8 4.3e-12 45.9 0.8 1.3 1 0 0 1 1 1 1 WW domain zf-CCCH PF00642.24 AIO01068.1 - 6.1e-06 26.0 0.8 1.1e-05 25.2 0.8 1.5 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 AIO01068.1 - 0.00025 21.0 1.4 0.00025 21.0 1.4 1.8 2 0 0 2 2 2 1 Zinc finger domain zf-CCCH_4 PF18044.1 AIO01068.1 - 0.0023 17.7 0.8 0.0023 17.7 0.8 1.8 2 0 0 2 2 2 1 CCCH-type zinc finger Torus PF16131.5 AIO01068.1 - 0.0082 16.8 0.2 0.0096 16.6 0.2 1.2 1 0 0 1 1 1 1 Torus domain zf-CCCH_2 PF14608.6 AIO01068.1 - 0.051 14.1 0.5 0.14 12.7 0.5 1.7 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger PUF PF00806.19 AIO01069.1 - 2.5e-19 67.8 0.0 0.049 13.3 0.0 8.8 10 0 0 10 10 10 6 Pumilio-family RNA binding repeat UPF0565 PF10561.9 AIO01069.1 - 0.18 11.0 0.6 1.2 8.3 0.4 2.2 2 0 0 2 2 2 0 Uncharacterised protein family UPF0565 DAZAP2 PF11029.8 AIO01071.1 - 0.021 15.7 0.2 0.08 13.9 0.2 2.0 1 0 0 1 1 1 0 DAZ associated protein 2 (DAZAP2) DNA_pol_phi PF04931.13 AIO01074.1 - 6.6 4.7 8.3 9.9 4.1 8.3 1.2 1 0 0 1 1 1 0 DNA polymerase phi Pkinase PF00069.25 AIO01076.1 - 2.4e-46 158.3 0.0 2.8e-44 151.5 0.0 2.6 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 AIO01076.1 - 1.7e-30 106.2 0.0 7.1e-30 104.1 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase PH PF00169.29 AIO01076.1 - 2.4e-07 31.2 0.0 4.4e-07 30.4 0.0 1.5 1 0 0 1 1 1 1 PH domain PH_9 PF15410.6 AIO01076.1 - 0.0076 16.6 0.0 0.018 15.4 0.0 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain Kinase-like PF14531.6 AIO01076.1 - 0.012 15.0 0.0 0.02 14.3 0.0 1.2 1 0 0 1 1 1 0 Kinase-like Sod_Fe_C PF02777.18 AIO01077.1 - 7.7e-39 132.0 0.5 1.5e-38 131.1 0.2 1.6 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.22 AIO01077.1 - 5.4e-21 74.9 0.2 1.8e-20 73.2 0.1 1.8 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, alpha-hairpin domain Ras PF00071.22 AIO01078.1 - 5.7e-36 123.6 0.0 6.9e-36 123.3 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 AIO01078.1 - 3.9e-32 111.0 0.0 5.6e-32 110.5 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 AIO01078.1 - 3.6e-10 39.6 0.0 4.8e-10 39.2 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 AIO01078.1 - 9.6e-07 28.4 0.0 1.2e-06 28.0 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 AIO01078.1 - 1.1e-06 28.3 0.0 0.00017 21.2 0.0 2.9 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 AIO01078.1 - 1.3e-05 24.7 0.0 2.3e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 AIO01078.1 - 1.4e-05 25.1 0.0 2.1e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase TniB PF05621.11 AIO01078.1 - 0.00046 19.7 0.0 0.025 14.0 0.0 2.4 3 0 0 3 3 3 1 Bacterial TniB protein ATP_bind_1 PF03029.17 AIO01078.1 - 0.00056 19.8 0.1 0.00088 19.1 0.0 1.4 1 1 0 1 1 1 1 Conserved hypothetical ATP binding protein MMR_HSR1_Xtn PF16897.5 AIO01078.1 - 0.0021 18.0 0.0 0.0039 17.2 0.0 1.4 1 0 0 1 1 1 1 C-terminal region of MMR_HSR1 domain RsgA_GTPase PF03193.16 AIO01078.1 - 0.0036 17.2 0.0 2.1 8.2 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase MCM PF00493.23 AIO01078.1 - 0.063 12.4 0.0 0.1 11.7 0.0 1.3 1 0 0 1 1 1 0 MCM P-loop domain AAA_16 PF13191.6 AIO01078.1 - 0.075 13.4 0.0 0.23 11.8 0.0 1.6 1 1 0 1 1 1 0 AAA ATPase domain Cpn60_TCP1 PF00118.24 AIO01079.1 - 9.8e-83 278.4 5.0 2.2e-82 277.3 5.0 1.5 1 1 0 1 1 1 1 TCP-1/cpn60 chaperonin family DOR PF14839.6 AIO01080.1 - 0.17 11.8 0.3 0.33 10.9 0.3 1.4 1 0 0 1 1 1 0 DOR family Cation_efflux PF01545.21 AIO01081.1 - 3e-06 27.1 8.8 5.3e-06 26.3 8.8 1.4 1 1 0 1 1 1 1 Cation efflux family COX7C PF02935.16 AIO01081.1 - 0.21 11.9 1.1 0.79 10.0 1.1 2.0 1 0 0 1 1 1 0 Cytochrome c oxidase subunit VIIc Dishevelled PF02377.15 AIO01081.1 - 0.6 10.5 5.6 1.3 9.4 5.6 1.5 1 0 0 1 1 1 0 Dishevelled specific domain TRP PF06011.12 AIO01081.1 - 0.98 8.1 6.3 3.1 6.4 0.2 2.1 2 0 0 2 2 2 0 Transient receptor potential (TRP) ion channel CBFD_NFYB_HMF PF00808.23 AIO01082.1 - 0.0023 18.2 0.0 0.0035 17.6 0.0 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone DUF647 PF04884.14 AIO01086.1 - 3.2e-32 112.1 9.4 5e-32 111.4 9.4 1.3 1 0 0 1 1 1 1 Vitamin B6 photo-protection and homoeostasis SpoOE-like PF09388.10 AIO01087.1 - 0.2 11.6 1.4 13 5.7 0.2 2.6 2 0 0 2 2 2 0 Spo0E like sporulation regulatory protein GED PF02212.18 AIO01087.1 - 2.1 8.5 7.4 0.79 9.9 2.8 2.4 2 0 0 2 2 2 0 Dynamin GTPase effector domain DnaJ_C PF01556.18 AIO01088.1 - 2.2e-32 112.2 0.0 3.1e-32 111.7 0.0 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 AIO01088.1 - 1.7e-15 56.9 0.5 2.6e-15 56.3 0.5 1.3 1 0 0 1 1 1 1 DnaJ domain Acyltransferase PF01553.21 AIO01090.1 - 8.2e-15 54.6 0.2 4.8e-14 52.1 0.0 2.0 2 0 0 2 2 2 1 Acyltransferase Lipase_GDSL_3 PF14606.6 AIO01090.1 - 0.15 12.2 0.0 0.24 11.5 0.0 1.3 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase family Ribo_biogen_C PF04034.13 AIO01092.1 - 5.7e-50 168.3 0.0 7.3e-50 167.9 0.0 1.1 1 0 0 1 1 1 1 Ribosome biogenesis protein, C-terminal RLI PF04068.15 AIO01092.1 - 4.1e-11 42.5 0.0 7.7e-11 41.6 0.0 1.4 1 0 0 1 1 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI Nop25 PF09805.9 AIO01093.1 - 0.026 15.0 4.6 0.029 14.8 4.6 1.2 1 0 0 1 1 1 0 Nucleolar protein 12 (25kDa) DUF4200 PF13863.6 AIO01094.1 - 1e-22 80.8 14.4 1e-22 80.8 14.4 3.9 4 0 0 4 4 4 2 Domain of unknown function (DUF4200) DUF2730 PF10805.8 AIO01094.1 - 3.5 7.8 9.6 26 5.0 0.4 4.0 4 0 0 4 4 4 0 Protein of unknown function (DUF2730) Endosulfine PF04667.17 AIO01095.1 - 0.00027 21.0 4.1 0.00047 20.2 4.1 1.6 1 1 0 1 1 1 1 cAMP-regulated phosphoprotein/endosulfine conserved region ANAPC_CDC26 PF10471.9 AIO01095.1 - 0.0073 17.1 0.9 0.0073 17.1 0.9 1.5 2 0 0 2 2 2 1 Anaphase-promoting complex APC subunit CDC26 DUF3456 PF11938.8 AIO01096.1 - 3.1e-27 96.0 0.6 6.4e-26 91.7 0.0 2.1 1 1 1 2 2 2 1 TLR4 regulator and MIR-interacting MSAP PEHE PF15275.6 AIO01096.1 - 1.4 9.5 4.3 0.56 10.8 0.8 2.0 2 0 0 2 2 2 0 PEHE domain MIR PF02815.19 AIO01097.1 - 0.035 14.0 0.0 0.069 13.0 0.0 1.5 1 0 0 1 1 1 0 MIR domain EMP24_GP25L PF01105.24 AIO01098.1 - 9.3e-32 110.4 0.1 1e-31 110.3 0.1 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Ras PF00071.22 AIO01099.1 - 6.4e-61 204.7 0.0 7.6e-61 204.4 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 AIO01099.1 - 8.7e-33 113.1 0.0 1.6e-32 112.2 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 AIO01099.1 - 3.9e-12 46.0 0.0 4.8e-12 45.7 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 AIO01099.1 - 0.00015 21.7 0.0 0.21 11.5 0.0 2.6 2 1 1 3 3 3 2 RsgA GTPase MMR_HSR1 PF01926.23 AIO01099.1 - 0.00026 21.0 0.0 0.00066 19.8 0.0 1.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 AIO01099.1 - 0.00067 19.2 0.0 0.0029 17.2 0.0 1.9 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 AIO01099.1 - 0.0012 18.2 0.0 0.0016 17.8 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_22 PF13401.6 AIO01099.1 - 0.037 14.3 0.0 0.1 12.9 0.0 1.8 2 1 0 2 2 2 0 AAA domain DAP3 PF10236.9 AIO01099.1 - 0.04 13.1 0.0 0.062 12.4 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 AAA_24 PF13479.6 AIO01099.1 - 0.14 11.9 0.0 0.2 11.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain TetR_C_16 PF17920.1 AIO01099.1 - 0.14 12.4 0.0 0.21 11.8 0.0 1.3 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain NECFESHC PF16621.5 AIO01100.1 - 0.007 16.3 0.2 0.028 14.4 0.2 2.0 1 0 0 1 1 1 1 SH3 terminal domain of 2nd SH3 on Neutrophil cytosol factor 1 DUF5617 PF18493.1 AIO01101.1 - 0.0048 17.0 0.1 0.0066 16.5 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF5617) ABC_tran PF00005.27 AIO01102.1 - 9.6e-18 65.0 0.0 2e-17 64.0 0.0 1.6 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 AIO01102.1 - 3.1e-09 37.1 0.5 6.2e-05 22.9 0.4 2.2 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 AIO01102.1 - 4.2e-08 32.9 0.1 5.3e-06 26.0 0.1 2.2 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain ABC_membrane PF00664.23 AIO01102.1 - 5.8e-06 26.2 8.5 1e-05 25.3 8.5 1.4 1 0 0 1 1 1 1 ABC transporter transmembrane region AAA_16 PF13191.6 AIO01102.1 - 0.00061 20.2 0.1 0.0018 18.7 0.1 1.9 1 1 0 1 1 1 1 AAA ATPase domain RsgA_GTPase PF03193.16 AIO01102.1 - 0.0016 18.4 0.4 0.0061 16.5 0.1 2.1 2 0 0 2 2 2 1 RsgA GTPase AAA_22 PF13401.6 AIO01102.1 - 0.005 17.1 1.9 0.0096 16.2 0.2 2.3 3 0 0 3 3 2 1 AAA domain AAA_23 PF13476.6 AIO01102.1 - 0.0086 16.6 0.0 0.014 15.9 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 AIO01102.1 - 0.022 15.2 0.1 0.16 12.4 0.0 2.4 3 0 0 3 3 2 0 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.6 AIO01102.1 - 0.024 14.4 0.1 0.054 13.3 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_25 PF13481.6 AIO01102.1 - 0.029 14.0 1.0 0.34 10.4 0.2 2.6 1 1 1 2 2 2 0 AAA domain Rad17 PF03215.15 AIO01102.1 - 0.039 13.9 0.3 0.083 12.8 0.3 1.5 1 0 0 1 1 1 0 Rad17 P-loop domain RNA_helicase PF00910.22 AIO01102.1 - 0.044 14.2 0.0 0.086 13.2 0.0 1.5 1 0 0 1 1 1 0 RNA helicase Adeno_IVa2 PF02456.15 AIO01102.1 - 0.055 12.3 0.1 0.092 11.5 0.1 1.2 1 0 0 1 1 1 0 Adenovirus IVa2 protein SbcCD_C PF13558.6 AIO01102.1 - 0.056 13.7 0.1 0.76 10.0 0.0 2.7 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit Creatininase PF02633.14 AIO01102.1 - 0.068 12.6 0.0 0.13 11.7 0.0 1.4 1 0 0 1 1 1 0 Creatinine amidohydrolase AAA_5 PF07728.14 AIO01102.1 - 0.12 12.3 0.1 0.26 11.3 0.1 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_15 PF13175.6 AIO01102.1 - 0.14 11.9 0.0 12 5.5 0.0 2.3 2 0 0 2 2 2 0 AAA ATPase domain ATPase_2 PF01637.18 AIO01102.1 - 0.2 11.6 0.1 0.43 10.4 0.1 1.5 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea CTP_transf_like PF01467.26 AIO01103.1 - 3.2e-07 30.6 0.0 6.5e-07 29.6 0.0 1.5 1 1 0 1 1 1 1 Cytidylyltransferase-like dCMP_cyt_deam_1 PF00383.23 AIO01104.1 - 1.1e-07 31.6 0.1 2.4e-07 30.5 0.1 1.7 1 1 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 AIO01104.1 - 1.7e-06 27.8 0.0 3.3e-06 26.9 0.0 1.4 1 0 0 1 1 1 1 MafB19-like deaminase Bd3614-deam PF14439.6 AIO01104.1 - 0.01 15.9 0.1 0.069 13.2 0.0 2.3 2 0 0 2 2 2 0 Bd3614-like deaminase Cons_hypoth95 PF03602.15 AIO01105.1 - 0.096 12.3 0.0 0.58 9.8 0.0 2.0 2 0 0 2 2 2 0 Conserved hypothetical protein 95 Methyltransf_31 PF13847.6 AIO01105.1 - 0.19 11.5 0.0 16 5.3 0.0 2.3 2 0 0 2 2 2 0 Methyltransferase domain MAD PF05557.13 AIO01106.1 - 0.019 13.4 15.6 0.01 14.3 11.2 2.0 2 0 0 2 2 2 0 Mitotic checkpoint protein DUF1192 PF06698.11 AIO01106.1 - 0.033 14.2 3.0 1 9.4 0.4 3.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) MbeD_MobD PF04899.12 AIO01106.1 - 0.11 12.6 6.0 0.067 13.3 1.9 2.7 2 0 0 2 2 2 0 MbeD/MobD like DMPK_coil PF08826.10 AIO01106.1 - 3.4 7.8 8.2 7.9 6.7 0.4 3.4 2 0 0 2 2 2 0 DMPK coiled coil domain like Lzipper-MIP1 PF14389.6 AIO01106.1 - 9.1 6.7 8.8 6 7.2 0.7 4.1 4 0 0 4 4 4 0 Leucine-zipper of ternary complex factor MIP1 Fungal_TACC PF12709.7 AIO01106.1 - 9.5 6.7 11.5 15 6.1 0.2 4.2 4 1 1 5 5 5 0 Fungal Transforming acidic coiled-coil (TACC) proteins LEA_3 PF03242.13 AIO01107.1 - 0.61 10.8 6.1 1.4 9.7 5.0 2.1 2 0 0 2 2 2 0 Late embryogenesis abundant protein RRM_1 PF00076.22 AIO01109.1 - 1.4e-06 28.0 0.0 2.5e-06 27.2 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CSTF2_hinge PF14327.6 AIO01109.1 - 9.4e-05 22.8 0.1 9.4e-05 22.8 0.1 2.3 3 0 0 3 3 3 1 Hinge domain of cleavage stimulation factor subunit 2 Nucleo_P87 PF07267.11 AIO01109.1 - 4.3 6.1 10.1 5.9 5.6 10.1 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Importin_rep_4 PF18808.1 AIO01111.1 - 4.4e-16 58.9 1.6 1.6e-13 50.7 0.0 4.1 4 0 0 4 4 4 1 Importin repeat HEAT_EZ PF13513.6 AIO01111.1 - 2.1e-12 47.3 4.1 0.46 11.0 0.0 6.5 6 0 0 6 6 6 4 HEAT-like repeat HEAT PF02985.22 AIO01111.1 - 1.6e-06 27.9 10.6 0.27 11.6 0.0 7.5 7 0 0 7 7 7 2 HEAT repeat HEAT_2 PF13646.6 AIO01111.1 - 2e-05 24.9 0.7 0.015 15.7 0.0 4.7 5 1 1 6 6 6 2 HEAT repeats Cnd1 PF12717.7 AIO01111.1 - 2.9e-05 24.2 0.6 0.0011 19.0 0.1 2.8 2 0 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 RTP1_C1 PF10363.9 AIO01111.1 - 0.00096 19.3 5.2 0.53 10.5 0.0 4.9 5 1 0 6 6 6 1 Required for nuclear transport of RNA pol II C-terminus 1 MMS19_C PF12460.8 AIO01111.1 - 0.11 11.6 3.8 25 3.8 0.3 4.0 5 0 0 5 5 5 0 RNAPII transcription regulator C-terminal Adaptin_N PF01602.20 AIO01111.1 - 1.3 7.5 4.5 2.5 6.6 0.0 3.4 4 1 0 4 4 4 0 Adaptin N terminal region Synaptobrevin PF00957.21 AIO01113.1 - 6.7e-09 35.4 4.2 1.4e-08 34.4 4.2 1.4 1 0 0 1 1 1 1 Synaptobrevin CSN8_PSD8_EIF3K PF10075.9 AIO01115.1 - 1.9e-15 57.1 0.0 3.2e-15 56.4 0.0 1.3 1 0 0 1 1 1 1 CSN8/PSMD8/EIF3K family PCI PF01399.27 AIO01115.1 - 0.0039 17.7 0.0 0.0058 17.1 0.0 1.4 1 0 0 1 1 1 1 PCI domain FPL PF09758.9 AIO01115.1 - 0.088 12.8 0.0 0.15 12.1 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised conserved protein DUF3378 PF11858.8 AIO01115.1 - 0.16 12.1 0.0 0.29 11.3 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3378) GTP_EFTU PF00009.27 AIO01117.1 - 6.5e-26 91.1 0.0 1e-25 90.4 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.24 AIO01117.1 - 7.4e-16 58.0 0.0 1.6e-15 56.9 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.6 AIO01117.1 - 1.6e-07 31.3 0.0 3.4e-07 30.3 0.0 1.5 1 0 0 1 1 1 1 Elongation Factor G, domain II MMR_HSR1 PF01926.23 AIO01117.1 - 1.3e-06 28.4 0.0 2.7e-06 27.4 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 AIO01117.1 - 1.2e-05 25.4 0.2 0.14 12.2 0.0 2.6 1 1 1 2 2 2 2 Dynamin family EFG_IV PF03764.18 AIO01117.1 - 0.0002 21.2 0.0 0.00046 20.0 0.0 1.5 1 0 0 1 1 1 1 Elongation factor G, domain IV Septin PF00735.18 AIO01117.1 - 0.00026 20.4 0.0 0.00042 19.7 0.0 1.2 1 0 0 1 1 1 1 Septin Roc PF08477.13 AIO01117.1 - 0.00047 20.4 0.0 0.0011 19.1 0.0 1.7 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 AIO01117.1 - 0.0028 17.1 0.0 0.0047 16.4 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.22 AIO01117.1 - 0.0071 15.9 0.0 0.014 15.0 0.0 1.4 1 0 0 1 1 1 1 Ras family AIG1 PF04548.16 AIO01117.1 - 0.036 13.4 0.1 0.3 10.4 0.0 2.1 2 0 0 2 2 2 0 AIG1 family TniB PF05621.11 AIO01117.1 - 0.062 12.7 0.0 0.12 11.8 0.0 1.4 1 0 0 1 1 1 0 Bacterial TniB protein EFTUD2 PF16004.5 AIO01117.1 - 0.12 13.0 3.3 4.5 7.9 3.3 2.3 1 1 0 1 1 1 0 116 kDa U5 small nuclear ribonucleoprotein component N-terminus RsgA_GTPase PF03193.16 AIO01117.1 - 0.15 12.0 0.4 1.6 8.6 0.0 2.3 2 0 0 2 2 2 0 RsgA GTPase Complex1_LYR PF05347.15 AIO01118.1 - 2.4e-12 46.7 0.3 2.4e-12 46.7 0.3 1.6 2 0 0 2 2 2 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.6 AIO01118.1 - 0.00083 19.9 0.2 0.0017 18.9 0.2 1.5 1 0 0 1 1 1 1 Complex1_LYR-like DUF4131 PF13567.6 AIO01118.1 - 0.03 14.0 0.0 0.053 13.2 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) HALZ PF02183.18 AIO01119.1 - 1.7 8.9 16.5 4.7 7.5 0.1 5.3 5 0 0 5 5 5 0 Homeobox associated leucine zipper FlaC_arch PF05377.11 AIO01119.1 - 6.8 7.2 17.7 6.5 7.2 0.1 5.6 4 1 1 5 5 5 0 Flagella accessory protein C (FlaC) Clr5 PF14420.6 AIO01120.1 - 0.59 10.4 4.9 9.2 6.6 0.3 3.1 2 1 0 2 2 2 0 Clr5 domain VitK2_biosynth PF02621.14 AIO01120.1 - 2.6 7.5 9.8 0.31 10.5 1.1 3.1 3 0 0 3 3 3 0 Menaquinone biosynthesis Spc7 PF08317.11 AIO01120.1 - 5.6 5.7 67.4 0.021 13.7 15.8 3.6 3 1 1 4 4 4 0 Spc7 kinetochore protein DEAD PF00270.29 AIO01121.1 - 2.2e-40 138.3 0.0 5.5e-40 137.0 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 AIO01121.1 - 6.3e-24 84.5 0.0 1.6e-23 83.2 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 AIO01121.1 - 5e-14 52.3 0.2 1.3e-13 50.9 0.2 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.15 AIO01121.1 - 0.064 13.2 0.0 0.14 12.2 0.0 1.5 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit Formyl_trans_N PF00551.19 AIO01122.1 - 1.1e-14 54.5 0.0 2.2e-14 53.6 0.0 1.3 1 0 0 1 1 1 1 Formyl transferase CS PF04969.16 AIO01124.1 - 0.0026 18.8 0.1 0.0045 18.0 0.1 1.4 1 0 0 1 1 1 1 CS domain AD PF09793.9 AIO01125.1 - 0.0056 16.8 0.0 0.0099 16.0 0.0 1.3 1 0 0 1 1 1 1 Anticodon-binding domain IMUP PF15761.5 AIO01125.1 - 0.14 12.9 0.8 0.24 12.1 0.8 1.4 1 0 0 1 1 1 0 Immortalisation up-regulated protein PAP2 PF01569.21 AIO01128.1 - 6.4e-18 64.8 3.1 6.4e-18 64.8 3.1 2.3 2 0 0 2 2 2 1 PAP2 superfamily PAP2_3 PF14378.6 AIO01128.1 - 0.00041 20.1 2.9 0.00041 20.1 2.9 3.3 5 0 0 5 5 5 1 PAP2 superfamily Big_4 PF07532.11 AIO01129.1 - 0.25 11.1 1.8 0.42 10.4 0.3 2.0 2 0 0 2 2 2 0 Bacterial Ig-like domain (group 4) ATG16 PF08614.11 AIO01129.1 - 2.1 8.5 16.2 6.4 7.0 10.7 2.3 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) ERG4_ERG24 PF01222.17 AIO01131.1 - 4.1e-124 414.6 1.8 4.7e-124 414.4 1.8 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF1295 PF06966.12 AIO01131.1 - 1.5e-07 31.2 0.1 3.5e-07 30.0 0.1 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) PEMT PF04191.13 AIO01131.1 - 0.0006 20.2 0.0 0.0022 18.4 0.0 2.0 1 0 0 1 1 1 1 Phospholipid methyltransferase ICMT PF04140.14 AIO01131.1 - 0.0027 18.1 0.0 0.0027 18.1 0.0 3.0 3 0 0 3 3 3 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family EamA PF00892.20 AIO01132.1 - 0.0068 16.6 11.6 0.013 15.7 11.6 1.5 1 1 0 1 1 1 1 EamA-like transporter family Tmemb_18A PF09771.9 AIO01132.1 - 0.051 14.0 1.4 0.065 13.6 0.7 1.5 1 1 1 2 2 2 0 Transmembrane protein 188 NAD_binding_1 PF00175.21 AIO01133.1 - 1e-18 68.0 0.0 3e-16 60.0 0.0 2.3 1 1 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 AIO01133.1 - 2.4e-12 47.0 0.0 3.9e-12 46.4 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.12 AIO01133.1 - 0.00021 21.4 0.0 0.00037 20.7 0.0 1.4 1 1 0 1 1 1 1 Ferric reductase NAD binding domain Nsp1_C PF05064.13 AIO01134.1 - 1.9e-06 27.7 0.2 3e-06 27.0 0.2 1.2 1 0 0 1 1 1 1 Nsp1-like C-terminal region Spc7 PF08317.11 AIO01134.1 - 0.027 13.4 3.3 0.037 12.9 3.3 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein PIN_8 PF18476.1 AIO01134.1 - 0.26 11.1 1.0 0.37 10.6 1.0 1.1 1 0 0 1 1 1 0 PIN like domain CENP-F_leu_zip PF10473.9 AIO01134.1 - 0.31 11.1 1.2 4.8 7.2 0.0 2.1 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 MGTL PF17059.5 AIO01135.1 - 2 8.4 4.9 1.4 8.8 0.3 2.7 2 0 0 2 2 2 0 MgtA leader peptide MIP PF00230.20 AIO01136.1 - 7.8e-31 107.5 17.8 9.7e-31 107.2 17.8 1.1 1 0 0 1 1 1 1 Major intrinsic protein DUF4271 PF14093.6 AIO01136.1 - 0.088 12.7 0.3 0.088 12.7 0.3 2.1 2 1 0 2 2 2 0 Domain of unknown function (DUF4271) Zeta_toxin PF06414.12 AIO01136.1 - 0.16 11.2 0.0 0.24 10.6 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin CitMHS PF03600.16 AIO01136.1 - 0.37 9.9 9.8 0.058 12.6 4.5 2.0 1 1 1 2 2 2 0 Citrate transporter UCR_Fe-S_N PF10399.9 AIO01136.1 - 5.6 6.4 7.3 0.72 9.2 2.3 2.2 2 0 0 2 2 2 0 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal CPP1-like PF11833.8 AIO01136.1 - 6.3 6.4 7.5 2.2 7.9 1.7 2.4 1 1 2 3 3 3 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like MIP PF00230.20 AIO01137.1 - 6.3e-30 104.6 16.4 8.5e-30 104.1 16.4 1.1 1 0 0 1 1 1 1 Major intrinsic protein DNA_pol_lambd_f PF10391.9 AIO01139.1 - 0.013 15.3 0.0 0.028 14.2 0.0 1.5 1 0 0 1 1 1 0 Fingers domain of DNA polymerase lambda TPR_12 PF13424.6 AIO01140.1 - 1.4e-06 28.4 4.8 1.4e-06 28.4 4.8 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat MIT PF04212.18 AIO01140.1 - 0.0067 16.5 1.5 0.015 15.4 0.5 2.1 2 0 0 2 2 2 1 MIT (microtubule interacting and transport) domain IQ PF00612.27 AIO01140.1 - 0.17 11.8 2.8 0.75 9.8 0.4 2.8 2 0 0 2 2 2 0 IQ calmodulin-binding motif TPR_1 PF00515.28 AIO01140.1 - 0.22 11.4 11.2 5.2 7.1 0.3 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_7 PF13176.6 AIO01140.1 - 2.4 8.4 8.2 9.2 6.6 0.1 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat Methyltr_RsmB-F PF01189.17 AIO01142.1 - 7.5e-30 104.1 0.0 1.1e-29 103.5 0.0 1.2 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F MTS PF05175.14 AIO01142.1 - 0.066 12.8 0.0 0.17 11.4 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase small domain NUDIX PF00293.28 AIO01143.1 - 0.00087 19.3 0.0 0.002 18.2 0.0 1.7 1 0 0 1 1 1 1 NUDIX domain MNSV_P7B PF06692.11 AIO01143.1 - 0.1 12.6 0.0 0.2 11.7 0.0 1.4 1 0 0 1 1 1 0 Melon necrotic spot virus P7B protein PAP_assoc PF03828.19 AIO01144.1 - 6.4e-09 35.9 0.0 1.2e-08 35.0 0.0 1.5 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.23 AIO01144.1 - 0.0015 18.8 0.0 0.0028 17.9 0.0 1.5 1 0 0 1 1 1 1 Nucleotidyltransferase domain Polbeta PF18765.1 AIO01144.1 - 0.2 11.7 0.0 0.35 11.0 0.0 1.4 1 0 0 1 1 1 0 Polymerase beta, Nucleotidyltransferase EBP50_C PF09007.11 AIO01145.1 - 7.7 7.5 13.8 6.9 7.7 4.8 3.8 3 0 0 3 3 3 0 EBP50, C-terminal ubiquitin PF00240.23 AIO01146.1 - 0.00048 19.8 0.0 0.00069 19.3 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin family TPR_14 PF13428.6 AIO01147.1 - 7.6e-06 26.3 37.4 2.4 9.2 1.9 10.6 8 2 2 10 10 10 2 Tetratricopeptide repeat TPR_2 PF07719.17 AIO01147.1 - 0.00021 21.1 5.7 0.006 16.6 1.6 4.8 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_17 PF13431.6 AIO01147.1 - 0.0028 17.9 5.4 6.4 7.4 0.1 5.3 5 0 0 5 5 5 1 Tetratricopeptide repeat PRP1_N PF06424.12 AIO01147.1 - 0.0044 17.4 0.4 0.0086 16.5 0.4 1.5 1 0 0 1 1 1 1 PRP1 splicing factor, N-terminal ANAPC3 PF12895.7 AIO01147.1 - 0.012 15.8 0.9 0.14 12.4 0.3 2.8 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_1 PF00515.28 AIO01147.1 - 0.068 13.0 1.2 0.36 10.7 1.2 2.4 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_12 PF13424.6 AIO01147.1 - 0.083 13.2 12.2 0.16 12.3 1.3 4.1 5 0 0 5 5 5 0 Tetratricopeptide repeat Trimer_CC PF08954.11 AIO01147.1 - 0.12 12.0 2.0 7.9 6.1 0.1 3.0 2 0 0 2 2 2 0 Trimerisation motif TPR_8 PF13181.6 AIO01147.1 - 0.2 12.0 2.9 14 6.2 0.9 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_9 PF13371.6 AIO01147.1 - 0.31 11.2 7.9 4.6 7.5 1.6 4.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_11 PF13414.6 AIO01147.1 - 2.8 7.7 5.2 32 4.3 2.4 2.8 2 0 0 2 2 2 0 TPR repeat TPR_4 PF07721.14 AIO01147.1 - 4.3 8.3 12.2 6.7 7.6 0.7 4.6 3 1 1 4 4 3 0 Tetratricopeptide repeat cNMP_binding PF00027.29 AIO01152.1 - 1.3e-09 38.0 0.0 0.0011 19.0 0.0 4.8 4 1 0 4 4 4 3 Cyclic nucleotide-binding domain HD PF01966.22 AIO01153.1 - 1e-07 32.2 0.0 2.9e-07 30.7 0.0 1.9 1 0 0 1 1 1 1 HD domain A_deaminase PF00962.22 AIO01154.1 - 1.9e-92 310.1 0.2 2.8e-68 230.7 0.1 2.3 2 0 0 2 2 2 2 Adenosine/AMP deaminase DUF4530 PF15039.6 AIO01154.1 - 0.013 15.6 0.0 0.036 14.2 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4530) DUF1192 PF06698.11 AIO01154.1 - 0.17 12.0 0.4 0.48 10.5 0.4 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1192) Ctr PF04145.15 AIO01155.1 - 0.046 14.4 0.1 0.31 11.6 0.0 2.2 2 0 0 2 2 2 0 Ctr copper transporter family CHCH PF06747.13 AIO01158.1 - 0.0034 17.5 3.7 0.0052 16.9 3.7 1.3 1 0 0 1 1 1 1 CHCH domain Colipase-like PF15083.6 AIO01158.1 - 0.015 15.4 1.1 0.022 14.9 1.1 1.3 1 0 0 1 1 1 0 Colipase-like MTCP1 PF08991.10 AIO01158.1 - 0.057 13.7 1.8 0.057 13.7 1.8 1.5 2 0 0 2 2 2 0 Mature-T-Cell Proliferation I type Complex1_LYR PF05347.15 AIO01161.1 - 0.00013 21.9 1.1 0.00037 20.5 1.1 1.8 1 1 0 1 1 1 1 Complex 1 protein (LYR family) Sod_Fe_C PF02777.18 AIO01162.1 - 2.3e-31 108.0 0.6 2.3e-31 108.0 0.6 2.0 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.22 AIO01162.1 - 9.3e-20 70.9 0.4 2.5e-19 69.5 0.4 1.8 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain Cys_Met_Meta_PP PF01053.20 AIO01163.1 - 7.2e-87 291.4 0.0 8.4e-87 291.2 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme SpoU_methylase PF00588.19 AIO01164.1 - 3.9e-27 95.1 0.2 5.8e-23 81.6 0.0 4.2 4 0 0 4 4 4 2 SpoU rRNA Methylase family Aa_trans PF01490.18 AIO01165.1 - 2.2e-51 174.9 28.6 2.7e-51 174.6 28.6 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 AIO01165.1 - 2.7e-10 39.9 12.6 6.6e-10 38.6 12.5 1.8 1 1 0 1 1 1 1 Tryptophan/tyrosine permease family AA_permease_2 PF13520.6 AIO01165.1 - 0.00011 21.2 20.1 0.00011 21.2 20.1 2.1 1 1 1 2 2 2 1 Amino acid permease VASt PF16016.5 AIO01167.1 - 3.7e-08 33.9 0.0 6.5e-08 33.1 0.0 1.3 1 0 0 1 1 1 1 VAD1 Analog of StAR-related lipid transfer domain Ribosomal_L27e PF01777.18 AIO01168.1 - 1.8e-25 89.1 1.6 2.6e-25 88.6 1.6 1.2 1 0 0 1 1 1 1 Ribosomal L27e protein family KOW PF00467.29 AIO01168.1 - 2.7e-05 24.0 1.3 3e-05 23.8 0.3 1.7 2 0 0 2 2 2 1 KOW motif APC1_C PF18122.1 AIO01169.1 - 0.085 12.8 0.3 0.31 11.0 0.2 2.1 2 0 0 2 2 2 0 Anaphase-promoting complex sub unit 1 C-terminal domain Ribosomal_L27e PF01777.18 AIO01170.1 - 1.8e-25 89.1 1.6 2.6e-25 88.6 1.6 1.2 1 0 0 1 1 1 1 Ribosomal L27e protein family KOW PF00467.29 AIO01170.1 - 2.7e-05 24.0 1.3 3e-05 23.8 0.3 1.7 2 0 0 2 2 2 1 KOW motif Sybindin PF04099.12 AIO01171.1 - 5.9e-22 78.1 0.0 6.9e-22 77.9 0.0 1.0 1 0 0 1 1 1 1 Sybindin-like family Sedlin_N PF04628.13 AIO01171.1 - 2.5e-07 30.9 0.0 2.6e-07 30.8 0.0 1.2 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Rhodanese PF00581.20 AIO01173.1 - 5.4e-08 33.3 0.0 7.5e-08 32.9 0.0 1.2 1 0 0 1 1 1 1 Rhodanese-like domain Sec7_N PF12783.7 AIO01174.1 - 6.3e-20 71.7 1.0 1.5e-19 70.4 1.0 1.6 1 0 0 1 1 1 1 Guanine nucleotide exchange factor in Golgi transport N-terminal Sec7 PF01369.20 AIO01174.1 - 3.7e-19 69.1 0.0 5.7e-19 68.5 0.0 1.3 1 0 0 1 1 1 1 Sec7 domain RFXA_RFXANK_bdg PF15289.6 AIO01175.1 - 0.016 15.5 0.2 0.05 13.9 0.2 1.8 1 0 0 1 1 1 0 Regulatory factor X-associated C-terminal binding domain RNase_T PF00929.24 AIO01178.1 - 2.6e-16 60.6 0.0 2.2e-09 38.1 0.0 2.8 2 1 0 2 2 2 2 Exonuclease DUF5051 PF16473.5 AIO01178.1 - 0.046 13.7 0.5 2.5 8.1 0.7 2.5 2 1 0 2 2 2 0 3' exoribonuclease, RNase T-like DNA_pol_A_exo1 PF01612.20 AIO01178.1 - 0.081 12.6 0.1 0.59 9.8 0.0 2.0 2 0 0 2 2 2 0 3'-5' exonuclease RRM_1 PF00076.22 AIO01180.1 - 1.1e-19 70.0 0.0 1.2e-06 28.2 0.0 3.7 3 1 1 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TyrRSs_C PF16714.5 AIO01180.1 - 0.068 13.0 0.0 0.17 11.7 0.0 1.6 1 0 0 1 1 1 0 Tyrosyl-tRNA synthetase C-terminal domain RPN7 PF10602.9 AIO01181.1 - 7.3e-48 162.5 0.7 1.7e-47 161.4 0.1 1.8 2 0 0 2 2 2 1 26S proteasome subunit RPN7 PCI PF01399.27 AIO01181.1 - 1.2e-15 57.9 0.2 4e-15 56.2 0.0 2.0 3 0 0 3 3 3 1 PCI domain IFT46_B_C PF12317.8 AIO01181.1 - 0.0091 15.7 0.0 0.02 14.6 0.0 1.5 1 0 0 1 1 1 1 Intraflagellar transport complex B protein 46 C terminal Prefoldin PF02996.17 AIO01183.1 - 4.8e-11 42.6 0.9 8e-11 41.9 0.1 1.8 2 0 0 2 2 2 1 Prefoldin subunit Prefoldin_3 PF13758.6 AIO01183.1 - 7.4e-06 25.9 3.2 0.00043 20.3 0.1 2.3 2 0 0 2 2 2 2 Prefoldin subunit Chibby PF14645.6 AIO01183.1 - 0.097 13.1 0.1 0.18 12.2 0.1 1.5 1 0 0 1 1 1 0 Chibby family CCDC106 PF15794.5 AIO01183.1 - 0.37 10.5 5.3 0.11 12.2 1.6 1.9 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 106 Cep57_CLD_2 PF14197.6 AIO01183.1 - 1 9.5 11.4 0.21 11.7 2.1 2.7 2 0 0 2 2 2 0 Centrosome localisation domain of PPC89 TPR_2 PF07719.17 AIO01184.1 - 3.4e-10 39.2 23.8 0.0067 16.4 0.5 6.5 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_1 PF00515.28 AIO01184.1 - 1.1e-07 31.3 21.7 0.077 12.9 0.4 6.4 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_16 PF13432.6 AIO01184.1 - 1.3e-07 32.1 5.0 3.5e-06 27.6 0.6 4.9 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_19 PF14559.6 AIO01184.1 - 1.1e-06 29.0 16.8 1.2e-05 25.8 0.9 5.0 4 1 0 4 4 4 2 Tetratricopeptide repeat CS PF04969.16 AIO01184.1 - 5.3e-05 24.2 0.3 0.00013 22.9 0.1 1.8 2 0 0 2 2 1 1 CS domain Fis1_TPR_C PF14853.6 AIO01184.1 - 0.0013 18.8 7.9 0.44 10.6 0.1 4.2 4 0 0 4 4 4 1 Fis1 C-terminal tetratricopeptide repeat ANAPC3 PF12895.7 AIO01184.1 - 0.029 14.6 12.1 1.9 8.8 0.9 3.7 3 0 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.6 AIO01184.1 - 0.039 14.8 32.9 0.12 13.2 0.1 7.3 5 3 2 7 7 7 0 Tetratricopeptide repeat TPR_8 PF13181.6 AIO01184.1 - 0.043 14.0 9.5 8 7.0 0.1 4.4 4 0 0 4 4 3 0 Tetratricopeptide repeat TPR_10 PF13374.6 AIO01184.1 - 0.079 12.9 11.1 0.53 10.2 0.3 5.1 6 0 0 6 6 5 0 Tetratricopeptide repeat XRN_M PF17846.1 AIO01184.1 - 0.082 11.9 1.0 0.15 11.0 1.0 1.4 1 0 0 1 1 1 0 Xrn1 helical domain TPR_12 PF13424.6 AIO01184.1 - 0.18 12.1 0.1 0.18 12.1 0.1 6.4 6 1 0 6 6 6 0 Tetratricopeptide repeat TPR_7 PF13176.6 AIO01184.1 - 9.7 6.5 21.3 3.9 7.7 0.2 6.2 7 0 0 7 7 6 0 Tetratricopeptide repeat FYVE PF01363.21 AIO01185.1 - 0.0053 16.9 10.6 0.012 15.7 10.6 1.6 1 0 0 1 1 1 1 FYVE zinc finger IBR PF01485.21 AIO01185.1 - 0.27 11.5 5.9 0.71 10.1 5.9 1.7 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain CTP_transf_1 PF01148.20 AIO01186.1 - 7.9e-32 111.1 1.2 1.5e-30 106.8 0.4 3.2 3 1 0 3 3 3 2 Cytidylyltransferase family COX4 PF02936.14 AIO01186.1 - 0.01 15.8 0.1 0.052 13.6 0.0 2.1 2 0 0 2 2 2 0 Cytochrome c oxidase subunit IV DUF778 PF05608.12 AIO01187.1 - 1.3e-73 247.5 0.0 2.5e-73 246.5 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF778) SNAP PF14938.6 AIO01189.1 - 9.4e-53 179.5 16.4 1.1e-52 179.3 16.4 1.0 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP TPR_14 PF13428.6 AIO01189.1 - 4.8e-06 26.9 7.4 2.5 9.2 0.0 5.3 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_12 PF13424.6 AIO01189.1 - 0.00086 19.5 7.1 1.5 9.2 0.5 4.2 1 1 3 5 5 5 4 Tetratricopeptide repeat Foie-gras_1 PF11817.8 AIO01189.1 - 0.0013 18.4 2.0 0.0035 17.0 2.0 1.7 1 1 0 1 1 1 1 Foie gras liver health family 1 Alkyl_sulf_dimr PF14863.6 AIO01189.1 - 0.0027 18.2 5.7 1 9.8 0.1 2.8 1 1 1 2 2 2 2 Alkyl sulfatase dimerisation TPR_MalT PF17874.1 AIO01189.1 - 0.0029 17.0 4.1 0.004 16.6 4.1 1.3 1 0 0 1 1 1 1 MalT-like TPR region TPR_19 PF14559.6 AIO01189.1 - 0.0042 17.6 7.9 0.35 11.4 2.0 2.9 2 0 0 2 2 2 2 Tetratricopeptide repeat DUF4363 PF14276.6 AIO01189.1 - 0.04 14.0 0.1 0.15 12.1 0.1 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4363) ANAPC3 PF12895.7 AIO01189.1 - 0.043 14.1 3.4 0.2 11.9 1.0 2.9 1 1 2 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 DUF1024 PF06260.12 AIO01189.1 - 0.16 12.3 1.5 13 6.2 0.1 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF1024) TPR_10 PF13374.6 AIO01189.1 - 0.28 11.1 2.4 24 5.0 0.0 3.9 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.17 AIO01189.1 - 0.95 9.7 15.6 54 4.3 0.0 5.7 5 1 1 6 6 6 0 Tetratricopeptide repeat AvrM_N PF18247.1 AIO01189.1 - 1.2 9.1 6.6 26 4.9 0.1 3.9 1 1 2 3 3 3 0 Flax-rust effector AvrM N-terminal domain TPR_6 PF13174.6 AIO01189.1 - 1.7 9.4 10.1 0.95 10.2 0.2 4.3 5 0 0 5 5 3 0 Tetratricopeptide repeat DUF728 PF05304.12 AIO01190.1 - 3.3 7.6 5.9 7.6 6.4 0.0 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF728) UCH PF00443.29 AIO01191.1 - 2.1e-49 168.4 0.0 3.1e-49 167.8 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 AIO01191.1 - 3.4e-12 46.6 4.9 1.2e-07 31.7 0.0 3.2 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase FG-GAP PF01839.23 AIO01192.1 - 0.0024 18.0 0.3 0.0058 16.7 0.3 1.6 1 0 0 1 1 1 1 FG-GAP repeat VCBS PF13517.6 AIO01192.1 - 0.013 16.1 0.0 0.063 13.9 0.1 2.2 2 0 0 2 2 2 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella TTL PF03133.15 AIO01193.1 - 1.2e-60 205.1 0.0 5.9e-45 153.6 0.0 2.2 2 0 0 2 2 2 2 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 AIO01193.1 - 3.7e-07 29.6 0.0 0.0014 18.0 0.0 2.4 2 0 0 2 2 2 2 YheC/D like ATP-grasp DUF1738 PF08401.11 AIO01194.1 - 0.00031 20.8 0.0 0.52 10.4 0.0 3.3 3 0 0 3 3 3 2 Domain of unknown function (DUF1738) NDK PF00334.19 AIO01195.1 - 8.3e-57 191.0 0.0 1.2e-56 190.5 0.0 1.2 1 0 0 1 1 1 1 Nucleoside diphosphate kinase NDK PF00334.19 AIO01196.1 - 5.5e-57 191.5 0.0 6.2e-57 191.4 0.0 1.0 1 0 0 1 1 1 1 Nucleoside diphosphate kinase PSI_PsaJ PF01701.18 AIO01196.1 - 0.1 13.1 0.0 0.16 12.5 0.0 1.3 1 0 0 1 1 1 0 Photosystem I reaction centre subunit IX / PsaJ MCM PF00493.23 AIO01197.1 - 6.3e-98 326.3 0.0 8.9e-98 325.8 0.0 1.2 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 AIO01197.1 - 1.8e-26 92.5 1.2 3.7e-26 91.4 1.2 1.5 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 AIO01197.1 - 1.8e-21 76.3 0.1 4.5e-21 75.1 0.1 1.7 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 AIO01197.1 - 1.1e-07 32.3 0.0 2.7e-07 31.1 0.0 1.7 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 AIO01197.1 - 1.2e-06 28.1 0.0 0.00015 21.2 0.0 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 AIO01197.1 - 4.8e-06 26.6 0.0 1.8e-05 24.8 0.0 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_lid_2 PF17863.1 AIO01197.1 - 0.0015 18.3 0.6 0.0041 16.9 0.6 1.8 1 0 0 1 1 1 1 AAA lid domain AAA_3 PF07726.11 AIO01197.1 - 0.018 14.9 0.0 0.054 13.4 0.0 1.8 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) HisKA PF00512.25 AIO01197.1 - 0.055 13.5 0.1 2.5 8.2 0.0 2.6 2 0 0 2 2 2 0 His Kinase A (phospho-acceptor) domain AAA PF00004.29 AIO01197.1 - 0.093 13.2 0.1 0.47 10.9 0.0 2.3 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 AIO01197.1 - 0.1 12.3 0.0 0.58 9.8 0.0 2.1 1 1 0 1 1 1 0 Sigma-54 interaction domain TBCA PF02970.16 AIO01198.1 - 6.4e-18 64.9 2.0 8.6e-18 64.5 2.0 1.2 1 0 0 1 1 1 1 Tubulin binding cofactor A Spc7 PF08317.11 AIO01198.1 - 0.00072 18.5 0.9 0.00087 18.3 0.9 1.1 1 0 0 1 1 1 1 Spc7 kinetochore protein DREV PF05219.12 AIO01198.1 - 0.0094 15.1 0.1 0.012 14.8 0.1 1.0 1 0 0 1 1 1 1 DREV methyltransferase HIP1_clath_bdg PF16515.5 AIO01198.1 - 0.018 15.6 3.5 0.024 15.2 3.5 1.2 1 0 0 1 1 1 0 Clathrin-binding domain of Huntingtin-interacting protein 1 CHASE3 PF05227.13 AIO01198.1 - 0.021 14.7 2.5 0.029 14.3 2.4 1.3 1 1 0 1 1 1 0 CHASE3 domain Herpes_U30 PF04523.13 AIO01198.1 - 0.057 11.3 0.4 0.067 11.1 0.4 1.0 1 0 0 1 1 1 0 Herpes virus tegument protein U30 FapA PF03961.13 AIO01198.1 - 0.061 11.9 1.0 0.069 11.8 1.0 1.0 1 0 0 1 1 1 0 Flagellar Assembly Protein A VGPC1_C PF16799.5 AIO01198.1 - 0.083 12.9 2.1 0.089 12.8 0.9 1.7 2 0 0 2 2 2 0 C-terminal membrane-localisation domain of ion-channel, VCN1 TSC22 PF01166.18 AIO01198.1 - 0.1 12.9 2.2 0.12 12.7 1.1 1.7 2 0 0 2 2 2 0 TSC-22/dip/bun family Fib_alpha PF08702.10 AIO01198.1 - 0.16 12.1 2.1 0.26 11.5 2.1 1.4 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family Phosducin PF02114.16 AIO01199.1 - 8.4e-11 41.3 0.1 9.4e-11 41.1 0.1 1.0 1 0 0 1 1 1 1 Phosducin Thioredoxin PF00085.20 AIO01199.1 - 7.5e-08 32.3 0.0 1.1e-07 31.7 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin TraF PF13728.6 AIO01199.1 - 0.002 18.0 0.0 0.0033 17.3 0.0 1.3 1 0 0 1 1 1 1 F plasmid transfer operon protein MnmE_helical PF12631.7 AIO01199.1 - 0.06 13.5 0.1 0.06 13.5 0.1 1.1 1 0 0 1 1 1 0 MnmE helical domain Thioredoxin_3 PF13192.6 AIO01199.1 - 0.09 12.8 0.0 0.19 11.8 0.0 1.5 1 0 0 1 1 1 0 Thioredoxin domain zf-C2H2_aberr PF17017.5 AIO01201.1 - 0.084 13.0 0.0 0.16 12.1 0.0 1.4 1 0 0 1 1 1 0 Aberrant zinc-finger Rab5ip PF07019.12 AIO01202.1 - 3.2e-18 66.1 8.4 3.7e-18 65.9 8.4 1.1 1 0 0 1 1 1 1 Rab5-interacting protein (Rab5ip) DUF21 PF01595.20 AIO01203.1 - 1e-36 126.3 3.9 1.6e-36 125.6 3.9 1.2 1 0 0 1 1 1 1 Cyclin M transmembrane N-terminal domain L_HMGIC_fpl PF10242.9 AIO01203.1 - 1.8 8.8 5.9 0.41 10.8 0.4 2.2 2 0 0 2 2 2 0 Lipoma HMGIC fusion partner-like protein LRR_4 PF12799.7 AIO01204.1 - 1.9e-16 59.9 15.6 1.8e-07 31.3 0.9 3.8 1 1 4 5 5 5 5 Leucine Rich repeats (2 copies) AMPK1_CBM PF16561.5 AIO01204.1 - 1.4e-13 50.8 0.0 2.9e-13 49.8 0.0 1.5 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase LRR_8 PF13855.6 AIO01204.1 - 4e-12 45.7 2.9 0.0018 18.0 0.3 3.4 3 0 0 3 3 3 3 Leucine rich repeat LRR_9 PF14580.6 AIO01204.1 - 1.3e-09 37.8 0.0 2e-05 24.2 0.0 2.4 1 1 1 2 2 2 2 Leucine-rich repeat SCAB-Ig PF16709.5 AIO01204.1 - 1.9e-08 34.3 0.0 0.11 12.6 0.0 4.1 4 0 0 4 4 4 2 Ig domain of plant-specific actin-binding protein LRR_6 PF13516.6 AIO01204.1 - 4.9e-05 23.0 7.6 12 6.3 0.5 5.1 4 0 0 4 4 4 3 Leucine Rich repeat LRR_1 PF00560.33 AIO01204.1 - 0.0067 16.8 3.7 32 5.6 0.0 5.3 4 1 0 4 4 4 0 Leucine Rich Repeat CBM_48 PF02922.18 AIO01204.1 - 0.11 12.9 0.0 0.64 10.4 0.0 2.3 3 0 0 3 3 3 0 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) MMR_HSR1 PF01926.23 AIO01205.1 - 9.7e-14 51.4 0.0 2.1e-13 50.4 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 AIO01205.1 - 9.5e-07 28.9 0.0 6.1e-05 23.0 0.0 2.6 2 0 0 2 2 2 1 RsgA GTPase GTP_EFTU PF00009.27 AIO01205.1 - 0.0033 17.0 0.0 0.25 10.9 0.0 2.7 2 1 1 3 3 3 1 Elongation factor Tu GTP binding domain ABC_tran PF00005.27 AIO01205.1 - 0.055 14.0 0.0 0.15 12.6 0.0 1.7 1 0 0 1 1 1 0 ABC transporter AAA_16 PF13191.6 AIO01205.1 - 0.059 13.7 0.0 0.19 12.1 0.0 1.8 1 0 0 1 1 1 0 AAA ATPase domain BRAP2 PF07576.12 AIO01205.1 - 0.13 12.5 0.1 0.24 11.7 0.1 1.4 1 0 0 1 1 1 0 BRCA1-associated protein 2 DnaJ PF00226.31 AIO01206.1 - 4.7e-21 74.7 0.0 9.5e-21 73.7 0.0 1.5 1 0 0 1 1 1 1 DnaJ domain Metallophos PF00149.28 AIO01207.1 - 1.6e-36 126.7 0.1 2.2e-36 126.3 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 AIO01207.1 - 0.022 15.2 0.1 0.048 14.1 0.1 1.5 1 0 0 1 1 1 0 Serine-threonine protein phosphatase N-terminal domain Roc PF08477.13 AIO01208.1 - 1e-14 54.8 0.0 2.3e-14 53.6 0.0 1.6 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 AIO01208.1 - 7.9e-12 45.1 0.1 1.8e-11 43.9 0.1 1.5 1 1 0 1 1 1 1 Ras family COR PF16095.5 AIO01208.1 - 2.6e-08 33.9 0.1 0.0057 16.5 0.0 2.3 2 0 0 2 2 2 2 C-terminal of Roc, COR, domain Gtr1_RagA PF04670.12 AIO01208.1 - 8.9e-05 21.9 0.0 0.00014 21.3 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region IBR PF01485.21 AIO01208.1 - 0.00037 20.6 0.1 0.00095 19.3 0.1 1.6 1 0 0 1 1 1 1 IBR domain, a half RING-finger domain YdjO PF14169.6 AIO01208.1 - 0.062 13.0 0.4 0.13 12.0 0.4 1.5 1 0 0 1 1 1 0 Cold-inducible protein YdjO Zn_Tnp_IS1 PF03811.13 AIO01208.1 - 0.12 12.2 1.6 0.29 10.9 0.2 2.5 3 0 0 3 3 3 0 InsA N-terminal domain zf-MIZ PF02891.20 AIO01211.1 - 1.7e-10 40.5 6.5 3.4e-10 39.5 6.5 1.5 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger zf-Nse PF11789.8 AIO01211.1 - 9e-07 28.6 1.7 1.8e-06 27.6 1.7 1.5 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit DZR PF12773.7 AIO01211.1 - 0.065 13.3 0.2 0.065 13.3 0.2 2.3 2 0 0 2 2 2 0 Double zinc ribbon zf-NADH-PPase PF09297.11 AIO01211.1 - 0.83 9.4 8.6 0.078 12.6 3.3 2.1 2 0 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain Zn-ribbon_8 PF09723.10 AIO01211.1 - 2.5 8.3 5.8 2.3 8.4 0.5 2.7 2 0 0 2 2 2 0 Zinc ribbon domain ABC_tran PF00005.27 AIO01212.1 - 6.2e-35 120.7 0.0 2.1e-34 119.0 0.0 1.9 3 0 0 3 3 2 1 ABC transporter ABC_membrane PF00664.23 AIO01212.1 - 1.8e-31 109.8 6.3 2.3e-31 109.4 6.3 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region SMC_N PF02463.19 AIO01212.1 - 4.9e-06 26.1 0.8 0.00062 19.3 0.8 2.4 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 AIO01212.1 - 0.00056 20.3 0.0 0.0014 19.1 0.0 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 AIO01212.1 - 0.0043 16.8 1.7 0.014 15.1 0.2 2.4 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_22 PF13401.6 AIO01212.1 - 0.0072 16.6 0.1 0.11 12.8 0.1 2.4 1 1 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 AIO01212.1 - 0.017 15.0 0.0 0.037 13.9 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase AAA_23 PF13476.6 AIO01212.1 - 0.032 14.7 0.3 0.14 12.7 0.2 1.9 1 1 0 2 2 2 0 AAA domain AAA_21 PF13304.6 AIO01212.1 - 0.041 13.7 0.0 0.073 12.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA PF00004.29 AIO01212.1 - 0.072 13.5 0.1 12 6.3 0.0 2.6 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 AIO01212.1 - 0.09 12.9 0.0 0.35 11.0 0.0 1.9 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 AIO01212.1 - 0.11 12.5 0.0 0.43 10.7 0.0 2.0 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_7 PF12775.7 AIO01212.1 - 0.12 11.9 0.0 0.24 10.9 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region FSH1 PF03959.13 AIO01214.1 - 1.4e-28 100.1 0.0 2e-28 99.5 0.0 1.2 1 0 0 1 1 1 1 Serine hydrolase (FSH1) MMR_HSR1_C PF08438.10 AIO01214.1 - 2.2e-23 83.0 0.0 5.6e-23 81.7 0.0 1.7 1 0 0 1 1 1 1 GTPase of unknown function C-terminal MMR_HSR1 PF01926.23 AIO01214.1 - 3.5e-15 56.1 0.0 1.1e-14 54.5 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 AIO01214.1 - 0.0013 18.2 0.0 0.0057 16.2 0.0 2.0 2 0 0 2 2 2 1 Ferrous iron transport protein B RWD PF05773.22 AIO01214.1 - 0.0054 17.0 0.0 0.011 16.0 0.0 1.5 1 0 0 1 1 1 1 RWD domain Hydrolase_4 PF12146.8 AIO01214.1 - 0.017 14.4 0.2 0.41 9.9 0.0 2.6 1 1 0 2 2 2 0 Serine aminopeptidase, S33 Ribosomal_L3 PF00297.22 AIO01215.1 - 2e-148 494.3 9.0 2.3e-148 494.1 9.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L3 Aldedh PF00171.22 AIO01216.1 - 3.6e-18 65.3 3.1 4e-13 48.7 0.7 2.3 2 0 0 2 2 2 2 Aldehyde dehydrogenase family YadA_anchor PF03895.15 AIO01216.1 - 0.16 12.1 0.4 0.46 10.6 0.4 1.7 1 0 0 1 1 1 0 YadA-like membrane anchor domain DUF1542 PF07564.11 AIO01216.1 - 1.7 8.8 4.7 3 8.0 1.0 2.6 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1542) IQ PF00612.27 AIO01217.1 - 1.6e-14 52.3 104.6 1.9e-05 24.0 3.6 12.8 12 0 0 12 12 12 8 IQ calmodulin-binding motif DUF480 PF04337.12 AIO01217.1 - 0.025 14.7 28.0 0.16 12.0 0.5 5.1 5 0 0 5 5 5 0 Protein of unknown function, DUF480 DUF4711 PF15829.5 AIO01217.1 - 0.025 14.5 0.1 0.1 12.5 0.1 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4711) TPR_10 PF13374.6 AIO01217.1 - 0.029 14.3 0.0 0.029 14.3 0.0 7.2 8 0 0 8 8 8 0 Tetratricopeptide repeat MKT1_C PF12246.8 AIO01217.1 - 0.071 12.3 0.1 0.15 11.3 0.1 1.4 1 0 0 1 1 1 0 Temperature dependent protein affecting M2 dsRNA replication YhfZ_C PF14503.6 AIO01217.1 - 1.1 8.7 7.5 27 4.2 0.2 3.4 3 0 0 3 3 3 0 YhfZ C-terminal domain LRR_6 PF13516.6 AIO01218.1 - 1.2e-07 31.2 4.7 0.11 12.6 0.1 4.8 5 0 0 5 5 5 3 Leucine Rich repeat LRR_4 PF12799.7 AIO01218.1 - 0.00017 21.9 1.2 0.0032 17.9 0.5 3.0 2 1 1 3 3 3 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 AIO01218.1 - 0.095 12.5 0.3 1.1 9.1 0.2 2.6 3 0 0 3 3 3 0 Leucine rich repeat L51_S25_CI-B8 PF05047.16 AIO01219.1 - 0.0084 16.0 0.1 0.013 15.4 0.1 1.4 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain Choline_kin_N PF04428.14 AIO01220.1 - 0.19 11.4 0.0 0.43 10.3 0.0 1.6 1 0 0 1 1 1 0 Choline kinase N terminus COG5 PF10392.9 AIO01221.1 - 2.1e-14 53.8 18.4 2.3e-12 47.2 2.0 4.3 3 1 1 4 4 4 2 Golgi transport complex subunit 5 DUF1664 PF07889.12 AIO01221.1 - 0.021 14.8 1.3 0.058 13.4 0.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) DUF4047 PF13256.6 AIO01221.1 - 0.042 14.0 1.1 0.082 13.1 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4047) DUF1351 PF07083.11 AIO01221.1 - 0.078 12.7 0.2 0.15 11.8 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1351) COG2 PF06148.11 AIO01221.1 - 3 7.9 6.9 3.2 7.8 2.9 3.2 3 1 0 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 Sigma70_ner PF04546.13 AIO01222.1 - 0.73 9.7 5.3 0.98 9.3 0.7 2.3 2 0 0 2 2 2 0 Sigma-70, non-essential region Roc PF08477.13 AIO01223.1 - 1.1e-07 32.1 0.2 9.6e-07 29.0 0.2 2.0 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 AIO01223.1 - 2.4e-05 23.9 0.4 0.0018 17.7 0.4 2.3 1 1 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.22 AIO01223.1 - 0.00043 19.9 0.0 0.0016 18.1 0.0 1.9 2 1 0 2 2 2 1 Ras family G-alpha PF00503.20 AIO01223.1 - 0.001 18.3 0.2 0.83 8.7 0.0 2.2 1 1 1 2 2 2 2 G-protein alpha subunit MMR_HSR1 PF01926.23 AIO01223.1 - 0.0072 16.4 0.0 0.012 15.6 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 AIO01223.1 - 0.014 15.5 0.0 0.04 14.0 0.1 1.7 1 1 1 2 2 2 0 Dynamin family PduV-EutP PF10662.9 AIO01223.1 - 0.028 14.1 0.0 0.075 12.8 0.0 1.7 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation GTP_EFTU PF00009.27 AIO01223.1 - 0.059 12.9 0.0 0.09 12.3 0.0 1.3 1 0 0 1 1 1 0 Elongation factor Tu GTP binding domain SRPRB PF09439.10 AIO01223.1 - 0.068 12.6 0.1 0.14 11.6 0.1 1.7 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_18 PF13238.6 AIO01223.1 - 0.069 13.7 0.0 0.14 12.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain CLP1_P PF16575.5 AIO01224.1 - 0.047 13.5 0.0 0.078 12.8 0.0 1.3 1 0 0 1 1 1 0 mRNA cleavage and polyadenylation factor CLP1 P-loop FAA_hydro_N_2 PF18288.1 AIO01224.1 - 0.071 13.5 1.0 0.16 12.4 0.1 2.0 2 0 0 2 2 2 0 Fumarylacetoacetase N-terminal domain 2 AAA_16 PF13191.6 AIO01225.1 - 8.3e-07 29.5 0.0 1.7e-06 28.5 0.0 1.6 1 1 0 1 1 1 1 AAA ATPase domain Roc PF08477.13 AIO01225.1 - 4.8e-06 26.8 0.0 2.3e-05 24.6 0.0 2.0 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase GTP_EFTU PF00009.27 AIO01225.1 - 5.2e-05 22.9 0.0 0.26 10.8 0.0 2.5 3 0 0 3 3 2 2 Elongation factor Tu GTP binding domain AAA_22 PF13401.6 AIO01225.1 - 0.00031 21.0 0.4 0.015 15.6 0.1 2.7 2 2 0 2 2 2 1 AAA domain NACHT PF05729.12 AIO01225.1 - 0.00061 19.8 0.0 0.0025 17.7 0.0 1.9 2 0 0 2 2 2 1 NACHT domain FtsK_SpoIIIE PF01580.18 AIO01225.1 - 0.0016 17.9 0.0 0.0032 16.9 0.0 1.5 1 0 0 1 1 1 1 FtsK/SpoIIIE family cobW PF02492.19 AIO01225.1 - 0.0025 17.4 0.1 0.024 14.2 0.1 2.2 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_19 PF13245.6 AIO01225.1 - 0.0029 17.9 0.0 0.0053 17.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain G-alpha PF00503.20 AIO01225.1 - 0.0034 16.6 0.0 0.054 12.6 0.0 2.2 2 0 0 2 2 2 1 G-protein alpha subunit AAA_33 PF13671.6 AIO01225.1 - 0.0038 17.4 1.0 0.037 14.2 0.8 2.5 1 1 0 1 1 1 1 AAA domain NB-ARC PF00931.22 AIO01225.1 - 0.0047 16.1 0.0 0.0087 15.3 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain ATP_bind_1 PF03029.17 AIO01225.1 - 0.0048 16.7 0.3 0.21 11.4 0.2 2.2 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein AAA_30 PF13604.6 AIO01225.1 - 0.0063 16.3 0.1 0.011 15.4 0.1 1.5 1 0 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 AIO01225.1 - 0.016 15.0 0.0 0.026 14.2 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase NTPase_1 PF03266.15 AIO01225.1 - 0.016 15.1 0.1 0.036 14.0 0.1 1.6 1 0 0 1 1 1 0 NTPase MCM PF00493.23 AIO01225.1 - 0.017 14.2 0.0 0.031 13.4 0.0 1.3 1 0 0 1 1 1 0 MCM P-loop domain ABC_tran PF00005.27 AIO01225.1 - 0.018 15.6 0.0 0.033 14.7 0.0 1.6 1 1 0 1 1 1 0 ABC transporter Arf PF00025.21 AIO01225.1 - 0.018 14.5 0.0 0.24 10.9 0.0 2.1 2 0 0 2 2 2 0 ADP-ribosylation factor family T2SSE PF00437.20 AIO01225.1 - 0.027 13.5 0.0 0.06 12.4 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_24 PF13479.6 AIO01225.1 - 0.029 14.1 0.3 0.24 11.1 0.0 2.6 2 1 1 3 3 3 0 AAA domain RsgA_GTPase PF03193.16 AIO01225.1 - 0.032 14.2 0.0 3 7.7 0.0 2.7 2 1 1 3 3 3 0 RsgA GTPase AAA_28 PF13521.6 AIO01225.1 - 0.043 14.1 0.1 0.11 12.7 0.0 1.8 2 0 0 2 2 1 0 AAA domain Zeta_toxin PF06414.12 AIO01225.1 - 0.047 13.0 0.0 0.091 12.0 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin AAA_29 PF13555.6 AIO01225.1 - 0.056 13.2 0.0 0.13 12.0 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 AIO01225.1 - 0.07 13.2 0.1 0.17 12.0 0.1 1.9 1 1 0 1 1 1 0 50S ribosome-binding GTPase DAP3 PF10236.9 AIO01225.1 - 0.074 12.2 0.0 0.12 11.5 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 AAA PF00004.29 AIO01225.1 - 0.076 13.4 0.0 0.17 12.3 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Septin PF00735.18 AIO01225.1 - 0.092 12.0 0.0 0.15 11.3 0.0 1.3 1 0 0 1 1 1 0 Septin Mg_chelatase PF01078.21 AIO01225.1 - 0.11 11.9 0.0 0.18 11.2 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Ploopntkinase3 PF18751.1 AIO01225.1 - 0.12 12.2 0.0 0.25 11.2 0.0 1.4 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 SRPRB PF09439.10 AIO01225.1 - 0.13 11.7 0.0 0.23 10.9 0.0 1.4 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit Pox_A32 PF04665.12 AIO01225.1 - 0.15 11.5 0.0 0.32 10.4 0.0 1.5 2 0 0 2 2 1 0 Poxvirus A32 protein AAA_18 PF13238.6 AIO01225.1 - 0.15 12.6 0.0 0.38 11.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain UvrD-helicase PF00580.21 AIO01225.1 - 0.16 11.5 0.1 0.27 10.7 0.1 1.3 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain AAA_17 PF13207.6 AIO01225.1 - 0.26 11.7 0.7 0.84 10.1 0.0 2.2 3 0 0 3 3 1 0 AAA domain Pkinase PF00069.25 AIO01227.1 - 3.3e-76 256.1 0.0 4.6e-76 255.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 AIO01227.1 - 6.7e-36 123.9 0.0 4.3e-35 121.3 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.22 AIO01227.1 - 0.0022 17.6 0.0 0.0045 16.6 0.0 1.4 1 0 0 1 1 1 1 RIO1 family FTA2 PF13095.6 AIO01227.1 - 0.016 14.9 0.0 6.5 6.3 0.0 2.3 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Haspin_kinase PF12330.8 AIO01227.1 - 0.029 13.3 0.1 0.049 12.6 0.1 1.3 1 0 0 1 1 1 0 Haspin like kinase domain APH PF01636.23 AIO01227.1 - 0.055 13.4 0.5 1.2 9.0 0.1 2.6 1 1 1 2 2 2 0 Phosphotransferase enzyme family Kinase-like PF14531.6 AIO01227.1 - 0.057 12.7 0.0 0.14 11.4 0.0 1.6 2 0 0 2 2 2 0 Kinase-like Seadorna_VP7 PF07387.11 AIO01227.1 - 0.064 12.3 0.0 0.1 11.6 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Glucosamine_iso PF01182.20 AIO01228.1 - 5.7e-21 75.4 0.0 7.1e-21 75.1 0.0 1.1 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase Phytoreo_S7 PF07236.11 AIO01228.1 - 0.047 12.0 0.1 0.058 11.8 0.1 1.1 1 0 0 1 1 1 0 Phytoreovirus S7 protein Cpn60_TCP1 PF00118.24 AIO01229.1 - 3.3e-144 481.2 11.1 3.8e-144 481.0 11.1 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family GlcNAc-1_reg PF18440.1 AIO01229.1 - 0.11 12.7 0.4 1.1 9.6 0.0 2.6 3 0 0 3 3 3 0 Putative GlcNAc-1 phosphotransferase regulatory domain DnaJ_C PF01556.18 AIO01232.1 - 3.4e-26 92.1 0.0 4.5e-26 91.7 0.0 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 AIO01232.1 - 3.9e-17 62.1 4.5 6.9e-17 61.3 4.5 1.4 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 AIO01232.1 - 1.7e-11 44.3 14.0 2.8e-11 43.6 14.0 1.4 1 0 0 1 1 1 1 DnaJ central domain Anti-TRAP PF15777.5 AIO01232.1 - 9.8e-07 28.6 7.9 0.004 17.1 1.3 2.4 2 0 0 2 2 2 2 Tryptophan RNA-binding attenuator protein inhibitory protein Arabinose_Isome PF02610.15 AIO01232.1 - 0.0053 16.0 0.2 0.0077 15.5 0.2 1.1 1 0 0 1 1 1 1 L-arabinose isomerase TackOD1 PF18551.1 AIO01232.1 - 0.0093 15.7 4.2 0.52 10.0 0.3 2.5 1 1 1 2 2 2 2 Thaumarchaeal output domain 1 DUF5402 PF17393.2 AIO01232.1 - 0.071 13.1 0.0 0.18 11.8 0.0 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5402) HypA PF01155.19 AIO01232.1 - 0.11 12.5 9.7 1.1 9.3 1.4 2.4 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DZR PF12773.7 AIO01232.1 - 0.23 11.5 10.5 1.8 8.7 10.5 2.1 1 1 0 1 1 1 0 Double zinc ribbon A2L_zn_ribbon PF08792.10 AIO01232.1 - 4.5 7.1 8.3 13 5.6 0.0 3.7 4 0 0 4 4 4 0 A2L zinc ribbon domain Pyr_redox_2 PF07992.14 AIO01233.1 - 4.7e-67 226.3 5.6 4.7e-67 226.3 5.6 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 AIO01233.1 - 5.2e-41 139.4 1.0 1.2e-40 138.2 1.0 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 AIO01233.1 - 9.4e-18 64.6 11.9 1.7e-16 60.6 2.1 3.1 3 1 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 AIO01233.1 - 6e-13 48.7 10.5 6.4e-11 42.1 0.0 3.0 4 0 0 4 4 4 2 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 AIO01233.1 - 2.2e-10 40.2 10.7 4.5e-09 35.9 4.7 2.7 2 1 0 2 2 2 2 Glucose inhibited division protein A FAD_oxidored PF12831.7 AIO01233.1 - 4.9e-10 39.3 1.1 4.9e-10 39.3 1.1 3.6 3 1 1 4 4 4 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 AIO01233.1 - 3.8e-07 30.2 6.2 4.2e-05 23.7 0.8 2.5 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 AIO01233.1 - 5.2e-06 25.8 3.2 5.2e-06 25.8 3.2 2.9 2 1 0 3 3 3 1 FAD binding domain K_oxygenase PF13434.6 AIO01233.1 - 4e-05 22.9 0.6 0.013 14.7 0.0 2.5 2 1 1 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Thi4 PF01946.17 AIO01233.1 - 5.2e-05 22.6 2.3 0.00037 19.8 0.2 2.5 2 0 0 2 2 2 1 Thi4 family AlaDh_PNT_C PF01262.21 AIO01233.1 - 7.6e-05 22.1 9.5 0.0038 16.6 0.4 3.3 3 1 1 4 4 4 2 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_3 PF01494.19 AIO01233.1 - 9.5e-05 21.8 12.9 0.02 14.2 0.6 3.2 2 1 1 3 3 3 3 FAD binding domain HI0933_like PF03486.14 AIO01233.1 - 0.00052 18.8 1.2 0.00052 18.8 1.2 3.8 3 1 1 4 4 4 1 HI0933-like protein 3HCDH_N PF02737.18 AIO01233.1 - 0.0012 18.8 6.4 0.003 17.5 0.5 3.4 2 1 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Lycopene_cycl PF05834.12 AIO01233.1 - 0.02 13.9 0.1 0.91 8.5 0.0 2.4 2 0 0 2 2 2 0 Lycopene cyclase protein XdhC_C PF13478.6 AIO01233.1 - 0.024 15.1 0.4 0.67 10.5 0.1 2.4 2 0 0 2 2 2 0 XdhC Rossmann domain UDPG_MGDP_dh_N PF03721.14 AIO01233.1 - 0.82 9.2 5.0 0.36 10.4 0.4 2.5 2 1 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain DAO PF01266.24 AIO01233.1 - 0.96 9.0 17.9 2.4 7.7 3.0 3.3 2 2 1 3 3 3 0 FAD dependent oxidoreductase NAD_binding_7 PF13241.6 AIO01233.1 - 6.5 7.2 7.6 2.2 8.8 1.2 2.9 3 1 0 3 3 2 0 Putative NAD(P)-binding Cyclin_N PF00134.23 AIO01234.1 - 1.1e-38 131.9 3.3 9.7e-38 128.8 0.6 2.1 2 0 0 2 2 2 2 Cyclin, N-terminal domain Cyclin_C PF02984.19 AIO01234.1 - 1.5e-31 108.9 0.0 3.9e-31 107.6 0.0 1.7 2 0 0 2 2 2 1 Cyclin, C-terminal domain Cyclin_C_2 PF16899.5 AIO01234.1 - 0.018 15.4 0.0 0.041 14.3 0.0 1.7 1 0 0 1 1 1 0 Cyclin C-terminal domain Na_H_antiporter PF03553.14 AIO01235.1 - 0.083 12.1 0.0 0.094 11.9 0.0 1.0 1 0 0 1 1 1 0 Na+/H+ antiporter family GTA_holin_3TM PF11351.8 AIO01235.1 - 0.62 10.6 5.2 0.67 10.5 0.4 2.0 1 1 1 2 2 2 0 Holin of 3TMs, for gene-transfer release zf-B_box PF00643.24 AIO01237.1 - 6.1e-08 32.7 3.7 1.6e-07 31.4 3.7 1.8 1 0 0 1 1 1 1 B-box zinc finger Lipase_3 PF01764.25 AIO01238.1 - 5.8e-10 39.2 0.0 2.6e-09 37.1 0.0 2.0 2 0 0 2 2 2 1 Lipase (class 3) Hydrolase_4 PF12146.8 AIO01238.1 - 0.047 13.0 0.1 0.11 11.7 0.0 1.6 2 0 0 2 2 2 0 Serine aminopeptidase, S33 Voltage_CLC PF00654.20 AIO01239.1 - 6.1e-79 265.8 24.6 6.1e-79 265.8 24.6 1.7 2 0 0 2 2 2 1 Voltage gated chloride channel CBS PF00571.28 AIO01239.1 - 9e-08 32.4 0.2 0.00022 21.6 0.1 2.6 2 0 0 2 2 2 2 CBS domain Romo1 PF10247.9 AIO01239.1 - 5.4 7.5 8.8 0.35 11.2 0.2 3.3 4 0 0 4 4 4 0 Reactive mitochondrial oxygen species modulator 1 TruD PF01142.18 AIO01240.1 - 2.1e-31 109.2 0.0 1.3e-27 96.7 0.0 3.2 2 1 0 2 2 2 2 tRNA pseudouridine synthase D (TruD) zf-MYND PF01753.18 AIO01241.1 - 0.0054 16.8 13.7 0.0054 16.8 13.7 2.4 2 0 0 2 2 2 1 MYND finger zf-Mss51 PF13824.6 AIO01241.1 - 0.0071 16.4 7.0 0.0071 16.4 7.0 2.2 2 0 0 2 2 2 1 Zinc-finger of mitochondrial splicing suppressor 51 zf-C2H2_4 PF13894.6 AIO01241.1 - 3.8 8.6 11.4 18 6.5 11.4 2.3 1 0 0 1 1 1 0 C2H2-type zinc finger Abhydrolase_1 PF00561.20 AIO01242.1 - 0.0002 21.1 1.2 0.00078 19.2 0.1 2.1 2 0 0 2 2 2 1 alpha/beta hydrolase fold UPF0564 PF10595.9 AIO01243.1 - 5.2e-09 35.6 22.8 4.6e-07 29.2 0.2 4.0 4 1 0 4 4 4 2 Uncharacterised protein family UPF0564 7TMR-HDED PF07697.11 AIO01243.1 - 3.2 7.8 8.0 1.6 8.8 3.0 2.6 3 0 0 3 3 3 0 7TM-HD extracellular RPA_interact_N PF14766.6 AIO01243.1 - 7.1 6.4 7.4 2.6 7.8 1.9 2.9 2 0 0 2 2 2 0 Replication protein A interacting N-terminal zf-C2HC_2 PF13913.6 AIO01245.1 - 3.1e-20 71.6 15.6 4.9e-09 35.9 0.5 3.9 3 0 0 3 3 3 3 zinc-finger of a C2HC-type zinc_ribbon_2 PF13240.6 AIO01245.1 - 0.00054 19.6 5.8 0.00054 19.6 5.8 3.5 3 0 0 3 3 3 1 zinc-ribbon domain zf-ribbon_3 PF13248.6 AIO01245.1 - 0.011 15.1 3.4 0.011 15.1 3.4 3.4 4 0 0 4 4 4 0 zinc-ribbon domain zf_UBZ PF18439.1 AIO01245.1 - 0.18 11.4 6.1 9.6 5.9 0.0 4.1 3 1 1 4 4 4 0 Ubiquitin-Binding Zinc Finger NOB1_Zn_bind PF08772.11 AIO01245.1 - 0.2 11.9 3.0 0.63 10.2 3.0 1.9 1 0 0 1 1 1 0 Nin one binding (NOB1) Zn-ribbon like zf-CHCC PF10276.9 AIO01245.1 - 0.44 10.6 3.4 0.6 10.2 0.1 2.7 3 0 0 3 3 3 0 Zinc-finger domain DZR PF12773.7 AIO01245.1 - 0.84 9.7 16.5 1.7 8.8 10.5 3.6 3 1 0 3 3 3 0 Double zinc ribbon zf-LYAR PF08790.11 AIO01245.1 - 1 9.3 4.8 17 5.4 0.9 3.1 3 0 0 3 3 3 0 LYAR-type C2HC zinc finger zinc_ribbon_15 PF17032.5 AIO01245.1 - 1 10.1 6.3 0.34 11.7 2.4 2.3 3 1 0 3 3 1 0 zinc-ribbon family DUF2318 PF10080.9 AIO01245.1 - 2.3 8.4 6.7 38 4.5 0.1 3.7 4 0 0 4 4 4 0 Predicted membrane protein (DUF2318) zf-RING_7 PF02591.15 AIO01245.1 - 2.9 8.1 7.6 42 4.4 0.1 3.9 3 1 1 4 4 4 0 C4-type zinc ribbon domain NinF PF05810.12 AIO01245.1 - 5.4 7.0 6.6 13 5.7 0.3 3.3 3 0 0 3 3 3 0 NinF protein RNase_PH PF01138.21 AIO01246.1 - 4.3e-06 27.2 0.0 7.3e-06 26.5 0.0 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 AIO01246.1 - 9.2e-05 22.4 0.0 0.00015 21.7 0.0 1.3 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 RRM_1 PF00076.22 AIO01247.1 - 3.1e-11 42.9 0.0 5.1e-08 32.6 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF3824 PF12868.7 AIO01247.1 - 0.49 11.0 3.2 1.1 9.9 3.2 1.6 1 0 0 1 1 1 0 Domain of unknwon function (DUF3824) DUF515 PF04415.12 AIO01247.1 - 0.98 7.7 4.7 1.5 7.1 4.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF515) Raf1_N PF18578.1 AIO01248.1 - 0.21 12.1 1.5 0.49 10.9 1.5 1.6 1 0 0 1 1 1 0 Rubisco accumulation factor 1 alpha helical domain TPR_19 PF14559.6 AIO01248.1 - 2.4 8.7 0.0 2.4 8.7 0.0 4.4 5 0 0 5 5 5 0 Tetratricopeptide repeat DEAD PF00270.29 AIO01249.1 - 6.3e-18 65.2 0.0 1.2e-17 64.3 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 AIO01249.1 - 0.00018 21.8 0.0 0.00062 20.1 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 AIO01249.1 - 0.00056 20.0 0.0 0.00093 19.2 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 AIO01249.1 - 0.014 15.6 0.0 10 6.4 0.0 2.9 2 0 0 2 2 2 0 AAA domain PhoH PF02562.16 AIO01249.1 - 0.023 14.2 0.0 0.039 13.4 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein AAA PF00004.29 AIO01249.1 - 0.048 14.1 0.1 0.75 10.2 0.0 2.4 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 AIO01249.1 - 0.076 12.7 0.0 0.31 10.7 0.0 2.0 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 AIO01249.1 - 0.089 12.5 0.0 0.65 9.7 0.0 2.2 2 0 0 2 2 2 0 IstB-like ATP binding protein Torus PF16131.5 AIO01251.1 - 2.1e-05 25.2 2.7 0.19 12.4 1.2 2.4 2 0 0 2 2 2 2 Torus domain zf-CCCH PF00642.24 AIO01251.1 - 0.00023 21.0 16.4 0.00066 19.5 1.5 2.4 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.6 AIO01251.1 - 0.0023 18.3 8.3 0.0044 17.5 2.8 2.8 2 0 0 2 2 2 1 RNA-binding, Nab2-type zinc finger zf_CCCH_4 PF18345.1 AIO01251.1 - 0.014 15.5 11.3 0.62 10.2 3.5 2.6 2 0 0 2 2 2 0 Zinc finger domain zf-CCCH_4 PF18044.1 AIO01251.1 - 0.092 12.6 14.3 0.19 11.5 2.8 2.4 2 0 0 2 2 2 0 CCCH-type zinc finger Robl_LC7 PF03259.17 AIO01253.1 - 6.2e-09 35.5 0.2 2.3e-08 33.7 0.0 1.8 2 0 0 2 2 2 1 Roadblock/LC7 domain LAMTOR5 PF16672.5 AIO01253.1 - 0.0011 18.8 0.1 0.0032 17.3 0.1 1.9 1 1 0 1 1 1 1 Ragulator complex protein LAMTOR5 Methyltr_RsmB-F PF01189.17 AIO01255.1 - 0.00016 21.4 0.0 0.00031 20.4 0.0 1.4 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F Glu_cyclase_2 PF05096.12 AIO01257.1 - 0.046 13.2 0.1 0.075 12.4 0.1 1.3 1 0 0 1 1 1 0 Glutamine cyclotransferase Pro-MCH PF05824.12 AIO01257.1 - 0.084 12.8 0.5 10 6.1 0.1 3.1 2 1 1 3 3 3 0 Pro-melanin-concentrating hormone (Pro-MCH) Band_3_cyto PF07565.13 AIO01257.1 - 0.17 11.6 3.8 0.24 11.2 3.8 1.3 1 0 0 1 1 1 0 Band 3 cytoplasmic domain TMF_TATA_bd PF12325.8 AIO01257.1 - 0.18 12.0 18.2 0.32 11.2 1.6 2.2 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding MscS_TM PF12794.7 AIO01257.1 - 0.39 9.5 6.0 0.68 8.7 6.0 1.3 1 0 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 Seryl_tRNA_N PF02403.22 AIO01257.1 - 1.6 9.0 9.7 1.3 9.3 0.5 2.8 2 1 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Spc24 PF08286.11 AIO01257.1 - 3.7 7.8 10.3 8.4 6.7 3.7 2.5 2 1 0 2 2 2 0 Spc24 subunit of Ndc80 PH PF00169.29 AIO01259.1 - 0.00032 21.2 0.0 0.00083 19.8 0.0 1.7 1 1 0 1 1 1 1 PH domain DUF2786 PF10979.8 AIO01260.1 - 0.25 11.3 4.1 0.84 9.6 4.1 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2786) ECH_2 PF16113.5 AIO01262.1 - 3.5e-88 296.3 0.0 3.9e-88 296.1 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_1 PF00378.20 AIO01262.1 - 2.3e-15 56.6 0.0 3.4e-15 56.0 0.0 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 AIO01263.1 - 1.7e-102 343.4 0.0 1.9e-102 343.2 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_1 PF00378.20 AIO01263.1 - 4.1e-21 75.4 0.0 2.2e-20 73.0 0.0 1.8 2 0 0 2 2 2 1 Enoyl-CoA hydratase/isomerase DUF4674 PF15719.5 AIO01265.1 - 0.01 15.9 1.6 0.01 15.9 1.6 1.8 2 1 0 2 2 2 1 Domain of unknown function (DUF4674) DUF2614 PF11023.8 AIO01265.1 - 0.099 12.7 0.1 0.14 12.3 0.1 1.3 1 0 0 1 1 1 0 Zinc-ribbon containing domain Rubredoxin_2 PF18073.1 AIO01265.1 - 0.11 12.2 0.3 0.11 12.2 0.3 2.1 2 0 0 2 2 2 0 Rubredoxin metal binding domain BT1 PF03092.16 AIO01266.1 - 1.5e-27 96.0 22.0 1.5e-16 59.7 6.5 2.1 2 0 0 2 2 2 2 BT1 family DUF3948 PF13134.6 AIO01266.1 - 1.8 8.3 6.3 0.35 10.6 0.8 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3948) TMEM18 PF14770.6 AIO01267.1 - 2.6e-28 98.4 0.5 3.4e-28 98.0 0.5 1.1 1 0 0 1 1 1 1 Transmembrane protein 18 Spexin PF15171.6 AIO01267.1 - 0.054 13.7 0.5 0.093 12.9 0.5 1.4 1 0 0 1 1 1 0 Neuropeptide secretory protein family, NPQ, spexin TYW3 PF02676.14 AIO01269.1 - 8.6e-48 162.5 0.0 9.9e-48 162.3 0.0 1.0 1 0 0 1 1 1 1 Methyltransferase TYW3 Tom5 PF10642.9 AIO01271.1 - 0.049 13.7 0.5 3.9 7.6 0.1 2.6 2 0 0 2 2 2 0 Mitochondrial import receptor subunit or translocase SufE PF02657.15 AIO01271.1 - 0.076 12.9 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 Fe-S metabolism associated domain GDWWSH PF15667.5 AIO01272.1 - 0.00024 20.6 0.4 0.00031 20.3 0.4 1.1 1 0 0 1 1 1 1 Protein of unknown function with motif GDWWSH CKS PF01111.19 AIO01273.1 - 7.9e-37 125.4 0.9 9.6e-37 125.1 0.9 1.1 1 0 0 1 1 1 1 Cyclin-dependent kinase regulatory subunit TPR_2 PF07719.17 AIO01274.1 - 1.2e-06 28.2 0.6 0.13 12.4 0.1 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 AIO01274.1 - 3.2e-06 26.7 0.6 0.1 12.4 0.0 3.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 AIO01274.1 - 0.004 17.4 0.9 0.31 11.4 0.0 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.6 AIO01274.1 - 0.035 14.3 0.0 1.9 8.9 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.6 AIO01274.1 - 0.37 11.5 5.0 26 5.7 0.1 4.5 4 1 1 5 5 5 0 Tetratricopeptide repeat SHQ1 PF04925.15 AIO01275.1 - 3.5e-34 117.9 0.0 6.3e-34 117.1 0.0 1.3 1 0 0 1 1 1 1 SHQ1 protein PsbQ PF05757.11 AIO01275.1 - 0.23 11.2 0.8 9.6 5.9 0.1 2.2 2 0 0 2 2 2 0 Oxygen evolving enhancer protein 3 (PsbQ) ANAPC4_WD40 PF12894.7 AIO01276.1 - 9.8e-05 22.6 0.0 2.4 8.5 0.0 3.9 2 2 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 AIO01276.1 - 0.0029 18.4 2.4 25 5.9 0.0 4.5 4 0 0 4 4 4 2 WD domain, G-beta repeat Cornichon PF03311.14 AIO01277.1 - 5.3e-14 52.6 9.5 5.3e-14 52.6 9.5 1.7 1 1 1 2 2 2 1 Cornichon protein Pox_P21 PF05313.12 AIO01277.1 - 0.01 15.4 1.0 0.01 15.4 1.0 2.6 1 1 2 3 3 3 0 Poxvirus P21 membrane protein 7tm_1 PF00001.21 AIO01277.1 - 7.5 5.8 11.2 8.1 5.7 8.7 2.1 1 1 1 2 2 2 0 7 transmembrane receptor (rhodopsin family) Cornichon PF03311.14 AIO01278.1 - 9.9e-24 84.0 1.5 9.9e-24 84.0 1.5 1.8 1 1 1 2 2 2 1 Cornichon protein HALZ PF02183.18 AIO01279.1 - 0.00049 20.2 1.6 1.3 9.3 0.2 3.4 3 0 0 3 3 3 1 Homeobox associated leucine zipper DUF1192 PF06698.11 AIO01279.1 - 0.00055 19.9 0.7 1.4 9.0 0.0 3.4 3 0 0 3 3 3 1 Protein of unknown function (DUF1192) Lzipper-MIP1 PF14389.6 AIO01279.1 - 0.0019 18.4 4.3 0.011 16.0 0.1 2.6 1 1 1 2 2 2 1 Leucine-zipper of ternary complex factor MIP1 Shugoshin_N PF07558.11 AIO01279.1 - 0.0049 16.7 2.7 0.0076 16.1 0.4 2.3 2 0 0 2 2 2 1 Shugoshin N-terminal coiled-coil region Mod_r PF07200.13 AIO01279.1 - 0.02 15.0 2.8 0.44 10.7 0.4 2.3 2 0 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein NEMO PF11577.8 AIO01279.1 - 0.031 14.3 2.0 3.5 7.7 0.2 2.5 2 0 0 2 2 2 0 NF-kappa-B essential modulator NEMO bZIP_1 PF00170.21 AIO01279.1 - 0.071 13.2 3.4 1.1 9.4 0.3 3.2 3 0 0 3 3 3 0 bZIP transcription factor CorA PF01544.18 AIO01279.1 - 0.12 11.6 5.6 0.77 9.0 2.7 2.1 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein ZapB PF06005.12 AIO01279.1 - 0.19 12.2 3.8 0.64 10.5 0.9 2.4 2 1 0 2 2 2 0 Cell division protein ZapB Cnn_1N PF07989.11 AIO01279.1 - 0.26 11.5 2.6 22 5.3 0.1 2.9 3 0 0 3 3 3 0 Centrosomin N-terminal motif 1 TSC22 PF01166.18 AIO01279.1 - 0.35 11.2 2.8 5.1 7.5 0.2 3.1 3 0 0 3 3 3 0 TSC-22/dip/bun family DivIVA PF05103.13 AIO01279.1 - 0.36 10.9 1.7 23 5.1 0.1 3.1 3 0 0 3 3 3 0 DivIVA protein Wtap PF17098.5 AIO01279.1 - 0.5 10.3 8.8 4.2 7.3 0.1 3.1 2 1 1 3 3 3 0 WTAP/Mum2p family bZIP_2 PF07716.15 AIO01279.1 - 1.8 8.7 8.2 5.2 7.2 0.8 3.2 3 0 0 3 3 3 0 Basic region leucine zipper CtIP_N PF10482.9 AIO01279.1 - 2.6 8.1 7.7 6.1 6.9 0.2 3.1 2 1 0 3 3 3 0 Tumour-suppressor protein CtIP N-terminal domain NYD-SP28_assoc PF14775.6 AIO01279.1 - 8.1 6.6 9.3 15 5.8 0.3 3.1 3 0 0 3 3 3 0 Sperm tail C-terminal domain DUF737 PF05300.11 AIO01280.1 - 0.25 11.7 0.0 0.25 11.7 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF737) Myosin_head PF00063.21 AIO01281.1 - 1.4e-176 588.7 0.1 2e-176 588.1 0.1 1.2 1 0 0 1 1 1 1 Myosin head (motor domain) UBA PF00627.31 AIO01281.1 - 8e-08 32.0 0.0 0.0083 16.0 0.0 3.2 3 0 0 3 3 3 2 UBA/TS-N domain AAA_lid_6 PF17866.1 AIO01281.1 - 0.0012 19.0 0.3 0.12 12.5 0.0 3.5 3 0 0 3 3 3 1 AAA lid domain AAA_22 PF13401.6 AIO01281.1 - 0.0019 18.5 0.0 0.032 14.5 0.0 3.0 3 0 0 3 3 3 1 AAA domain AAA_16 PF13191.6 AIO01281.1 - 0.0025 18.2 0.4 0.49 10.7 0.0 3.1 3 0 0 3 3 3 1 AAA ATPase domain CUE PF02845.16 AIO01281.1 - 0.0076 15.9 0.1 1.6 8.5 0.3 3.4 3 0 0 3 3 3 1 CUE domain Mg_chelatase PF01078.21 AIO01281.1 - 0.02 14.3 0.0 0.053 12.9 0.0 1.7 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Peptidase_M16_C PF05193.21 AIO01281.1 - 0.044 13.8 0.0 0.085 12.9 0.0 1.5 1 0 0 1 1 1 0 Peptidase M16 inactive domain DUF1640 PF07798.11 AIO01281.1 - 0.06 13.4 0.9 0.16 12.0 0.9 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1640) Myosin_N PF02736.19 AIO01281.1 - 0.071 13.0 0.1 0.33 10.8 0.1 2.2 3 0 0 3 3 3 0 Myosin N-terminal SH3-like domain AAA_18 PF13238.6 AIO01281.1 - 0.076 13.6 0.1 12 6.5 0.0 2.9 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 AIO01281.1 - 5 6.3 6.5 1.1 8.5 0.0 2.8 4 0 0 4 4 4 0 Zeta toxin Peptidase_C54 PF03416.19 AIO01283.1 - 1.6e-42 145.9 0.0 2e-42 145.5 0.0 1.1 1 0 0 1 1 1 1 Peptidase family C54 Ribosomal_L2_C PF03947.18 AIO01284.1 - 5.5e-43 146.2 3.5 1.2e-42 145.1 2.1 2.0 2 0 0 2 2 2 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.23 AIO01284.1 - 4.2e-13 49.1 0.1 1.2e-12 47.6 0.1 1.8 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain COPIIcoated_ERV PF07970.12 AIO01285.1 - 8.7e-36 123.8 0.1 1.2e-35 123.4 0.1 1.1 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.6 AIO01285.1 - 8.3e-26 90.2 0.7 1.5e-25 89.3 0.7 1.5 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) ERCC3_RAD25_C PF16203.5 AIO01286.1 - 2.8e-70 236.3 0.0 5.7e-70 235.3 0.0 1.5 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase Helicase_C_3 PF13625.6 AIO01286.1 - 1.1e-19 70.9 0.1 2.3e-19 69.8 0.1 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 AIO01286.1 - 3.6e-13 49.9 0.0 6.4e-13 49.1 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 AIO01286.1 - 1.1e-10 41.8 0.0 2.5e-10 40.7 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.23 AIO01286.1 - 1.3e-05 24.1 0.0 5.6e-05 22.0 0.0 1.9 2 0 0 2 2 2 1 SNF2 family N-terminal domain HECT PF00632.25 AIO01287.1 - 3.9e-37 128.4 0.1 9.2e-37 127.2 0.1 1.6 1 1 0 1 1 1 1 HECT-domain (ubiquitin-transferase) SPRY PF00622.28 AIO01287.1 - 2.3e-27 95.5 0.0 2.9e-07 30.6 0.0 4.8 5 0 0 5 5 5 4 SPRY domain ZZ PF00569.17 AIO01287.1 - 0.0011 18.8 9.7 0.0028 17.4 9.7 1.7 1 0 0 1 1 1 1 Zinc finger, ZZ type zf-UBR PF02207.20 AIO01287.1 - 0.0015 18.7 3.4 0.0058 16.8 3.4 2.0 1 0 0 1 1 1 1 Putative zinc finger in N-recognin (UBR box) PIN_4 PF13638.6 AIO01288.1 - 0.0073 16.6 0.0 0.049 13.9 0.0 2.3 1 1 0 1 1 1 1 PIN domain PG_binding_1 PF01471.18 AIO01290.1 - 0.012 15.9 0.4 0.084 13.1 0.0 2.5 3 0 0 3 3 3 0 Putative peptidoglycan binding domain CARD_2 PF16739.5 AIO01290.1 - 0.023 14.7 0.0 0.089 12.8 0.0 1.9 2 0 0 2 2 2 0 Caspase recruitment domain cNMP_binding PF00027.29 AIO01291.1 - 1.2e-21 76.5 0.0 1.9e-08 34.3 0.0 4.0 3 1 0 3 3 3 3 Cyclic nucleotide-binding domain 7TM_GPCR_Sri PF10327.9 AIO01291.1 - 0.011 15.0 0.1 0.02 14.1 0.1 1.3 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Sri GCM PF03615.15 AIO01291.1 - 0.08 12.8 0.1 0.21 11.5 0.1 1.7 1 0 0 1 1 1 0 GCM motif protein Gar1 PF04410.14 AIO01292.1 - 1.5e-24 86.6 0.0 2.3e-24 85.9 0.0 1.3 1 0 0 1 1 1 1 Gar1/Naf1 RNA binding region Glycos_transf_2 PF00535.26 AIO01293.1 - 2.7e-06 27.3 0.0 5.6e-06 26.3 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 2 zf_PR_Knuckle PF18445.1 AIO01295.1 - 0.16 11.8 0.2 0.16 11.8 0.2 2.0 2 0 0 2 2 2 0 PR zinc knuckle motif LysM PF01476.20 AIO01296.1 - 3.1e-07 30.3 0.0 0.056 13.5 0.0 3.1 3 0 0 3 3 3 2 LysM domain HTH_AsnC-type PF13404.6 AIO01296.1 - 0.02 14.7 1.1 2.4 8.1 0.0 3.1 3 0 0 3 3 3 0 AsnC-type helix-turn-helix domain HTH_23 PF13384.6 AIO01296.1 - 0.17 11.7 0.1 3.6 7.5 0.0 2.9 3 0 0 3 3 3 0 Homeodomain-like domain DUF3606 PF12244.8 AIO01296.1 - 0.22 11.5 1.5 1.3 9.0 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF3606) Herpes_UL52 PF03121.15 AIO01298.1 - 5.6e-12 45.4 0.2 2e-11 43.7 0.1 1.9 2 0 0 2 2 2 1 Herpesviridae UL52/UL70 DNA primase WD40 PF00400.32 AIO01301.1 - 3.5e-27 94.1 14.2 4.6e-07 30.4 0.5 7.7 8 0 0 8 8 8 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 AIO01301.1 - 1.2e-14 54.3 0.3 0.016 15.5 0.0 5.5 2 1 4 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain PQQ_2 PF13360.6 AIO01301.1 - 0.0023 17.6 0.0 0.011 15.4 0.0 1.9 2 1 0 2 2 2 1 PQQ-like domain Ge1_WD40 PF16529.5 AIO01301.1 - 0.045 12.7 4.6 12 4.7 0.1 3.7 2 2 1 4 4 4 0 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 AIO01301.1 - 0.051 12.9 0.0 0.35 10.1 0.0 2.1 1 1 0 2 2 2 0 WD40-like domain Frtz PF11768.8 AIO01301.1 - 0.094 11.0 0.0 4.7 5.4 0.0 2.8 2 1 0 3 3 3 0 WD repeat-containing and planar cell polarity effector protein Fritz WDCP PF15390.6 AIO01301.1 - 0.12 10.8 0.1 0.17 10.2 0.1 1.3 1 0 0 1 1 1 0 WD repeat and coiled-coil-containing protein family Sen15 PF09631.10 AIO01301.1 - 0.12 12.7 0.0 0.45 10.8 0.0 2.0 2 0 0 2 2 2 0 Sen15 protein HEAT PF02985.22 AIO01302.1 - 3.7e-05 23.6 2.4 0.25 11.7 0.0 5.2 6 0 0 6 6 6 2 HEAT repeat UVR PF02151.19 AIO01302.1 - 0.0022 17.7 7.6 0.0096 15.6 0.4 2.7 2 0 0 2 2 2 2 UvrB/uvrC motif RecX PF02631.16 AIO01303.1 - 0.061 13.8 0.8 0.11 13.0 0.8 1.3 1 0 0 1 1 1 0 RecX family Zip PF02535.22 AIO01305.1 - 3.3e-13 49.6 13.3 2.2e-08 33.7 0.6 3.2 2 1 1 3 3 3 3 ZIP Zinc transporter YrhC PF14143.6 AIO01305.1 - 8.7 6.5 6.1 15 5.8 0.1 3.1 4 0 0 4 4 4 0 YrhC-like protein CEP19 PF14933.6 AIO01308.1 - 5.4e-54 182.9 0.0 7.9e-54 182.4 0.0 1.2 1 0 0 1 1 1 1 CEP19-like protein Nop PF01798.18 AIO01309.1 - 8.3e-47 159.6 0.0 9.9e-47 159.3 0.0 1.1 1 0 0 1 1 1 1 snoRNA binding domain, fibrillarin Aminotran_1_2 PF00155.21 AIO01309.1 - 0.036 13.2 0.0 0.046 12.9 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class I and II Ank_2 PF12796.7 AIO01310.1 - 1e-12 48.4 0.1 5e-10 39.8 0.0 2.6 2 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 AIO01310.1 - 2.8e-07 30.3 0.9 0.0073 16.7 0.1 3.6 3 0 0 3 3 3 2 Ankyrin repeat Ank PF00023.30 AIO01310.1 - 2.9e-07 30.6 7.1 2.6e-06 27.6 0.3 3.8 5 0 0 5 5 5 1 Ankyrin repeat Ank_5 PF13857.6 AIO01310.1 - 3.8e-06 27.1 1.3 0.0033 17.7 0.2 3.2 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 AIO01310.1 - 4.7e-06 27.0 0.1 0.0035 17.9 0.1 2.9 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Iwr1 PF08574.10 AIO01311.1 - 2.6e-05 25.2 2.8 2.6e-05 25.2 2.8 2.2 3 0 0 3 3 3 1 Transcription factor Iwr1 Nuc_sug_transp PF04142.15 AIO01312.1 - 0.0075 15.5 0.0 0.014 14.6 0.0 1.4 1 0 0 1 1 1 1 Nucleotide-sugar transporter TrbC PF04956.13 AIO01312.1 - 0.3 11.3 3.3 3.3 8.0 0.1 3.3 1 1 2 3 3 3 0 TrbC/VIRB2 family Tetraspanin PF00335.20 AIO01313.1 - 7e-09 35.7 19.4 1.3e-08 34.8 19.4 1.4 1 1 0 1 1 1 1 Tetraspanin family DUF5367 PF17329.2 AIO01313.1 - 0.078 13.1 0.3 0.078 13.1 0.3 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF5367) RIF5_SNase_1 PF18187.1 AIO01314.1 - 9e-79 262.7 0.9 2.4e-78 261.4 0.9 1.8 1 0 0 1 1 1 1 TbRIF5 SNase domain 1 RIF5_SNase_2 PF18189.1 AIO01314.1 - 1.8e-68 229.3 0.1 4.8e-68 227.9 0.1 1.8 1 0 0 1 1 1 1 TbRIF5 SNase domain 2 TRAM1 PF08390.11 AIO01314.1 - 0.044 13.4 0.0 0.1 12.3 0.0 1.5 1 0 0 1 1 1 0 TRAM1-like protein Wzz PF02706.15 AIO01315.1 - 0.027 14.8 0.4 0.064 13.6 0.1 1.8 2 0 0 2 2 2 0 Chain length determinant protein DUF3762 PF12591.8 AIO01315.1 - 0.06 13.6 0.1 0.15 12.3 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3762) Peptidase_M14 PF00246.24 AIO01316.1 - 4e-11 43.3 0.0 9.3e-11 42.1 0.0 1.5 1 0 0 1 1 1 1 Zinc carboxypeptidase Pepdidase_M14_N PF18027.1 AIO01316.1 - 3.3e-08 33.9 0.1 1.3e-07 31.9 0.0 2.1 2 0 0 2 2 2 1 Cytosolic carboxypeptidase N-terminal domain PMP1_2 PF08114.11 AIO01317.1 - 0.081 12.7 0.6 0.29 10.9 0.6 1.9 1 0 0 1 1 1 0 ATPase proteolipid family LPD30 PF18850.1 AIO01317.1 - 0.089 12.6 0.0 0.17 11.7 0.0 1.4 1 0 0 1 1 1 0 Large polyvalent protein associated domain 30 DUF4926 PF16277.5 AIO01318.1 - 0.091 12.1 0.2 0.19 11.1 0.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4926) DHHC PF01529.20 AIO01319.1 - 2.6e-43 147.4 7.6 2.6e-43 147.4 7.6 2.0 3 0 0 3 3 3 1 DHHC palmitoyltransferase A_deamin PF02137.18 AIO01320.1 - 3.9e-20 72.6 0.0 6.5e-20 71.8 0.0 1.4 1 0 0 1 1 1 1 Adenosine-deaminase (editase) domain GST_C_5 PF16865.5 AIO01321.1 - 4e-87 287.9 0.9 1.9e-46 157.1 0.1 2.4 2 0 0 2 2 2 2 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 AIO01321.1 - 6.2e-30 103.4 0.1 1.9e-13 50.6 0.0 2.6 2 0 0 2 2 2 2 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 AIO01321.1 - 1.9e-26 92.1 0.2 8.7e-13 48.4 0.0 2.4 2 0 0 2 2 2 2 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 AIO01321.1 - 1.8e-19 69.8 0.1 4.4e-09 36.6 0.0 2.6 2 0 0 2 2 2 2 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 AIO01321.1 - 4.3e-15 55.5 1.5 1.1e-06 28.5 0.1 2.6 2 0 0 2 2 2 2 Glutathione S-transferase, C-terminal domain Glutaredoxin PF00462.24 AIO01321.1 - 2.4e-11 43.7 0.8 2.9e-08 33.8 0.3 2.4 2 0 0 2 2 2 2 Glutaredoxin GST_C_3 PF14497.6 AIO01321.1 - 4.1e-06 26.9 0.1 0.0027 17.9 0.0 2.6 2 0 0 2 2 2 2 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 AIO01321.1 - 0.00011 22.4 0.2 0.04 14.1 0.0 2.7 2 1 0 2 2 2 2 Glutathione S-transferase, C-terminal domain RRM_1 PF00076.22 AIO01323.1 - 8.4e-11 41.5 0.0 1.4e-10 40.9 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 AIO01323.1 - 0.00083 19.2 0.0 0.0014 18.5 0.0 1.3 1 0 0 1 1 1 1 Occluded RNA-recognition motif RRM_3 PF08777.11 AIO01323.1 - 0.0016 18.5 0.0 0.0031 17.5 0.0 1.6 1 1 0 1 1 1 1 RNA binding motif DUF2169 PF09937.9 AIO01323.1 - 0.041 13.3 0.0 5.8 6.3 0.0 2.1 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2169) Mpv17_PMP22 PF04117.12 AIO01324.1 - 2.5e-07 30.8 2.0 2.7e-07 30.7 0.8 1.7 2 0 0 2 2 2 1 Mpv17 / PMP22 family WD40 PF00400.32 AIO01325.1 - 3.2e-19 68.9 9.9 0.0049 17.7 0.0 7.0 6 1 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 AIO01325.1 - 3.4e-06 27.3 0.0 0.91 9.9 0.0 4.7 3 2 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain CSTF1_dimer PF16699.5 AIO01325.1 - 0.0041 16.9 0.0 0.011 15.5 0.0 1.7 1 0 0 1 1 1 1 Cleavage stimulation factor subunit 1, dimerisation domain Cytochrom_D1 PF02239.16 AIO01325.1 - 0.047 12.2 0.0 0.47 8.9 0.0 2.1 2 1 0 2 2 2 0 Cytochrome D1 heme domain Ge1_WD40 PF16529.5 AIO01325.1 - 0.072 12.0 0.0 6.9 5.5 0.0 2.9 3 0 0 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein LAL_C2 PF18603.1 AIO01325.1 - 0.093 12.9 1.7 0.16 12.2 0.3 2.1 2 0 0 2 2 2 0 L-amino acid ligase C-terminal domain 2 GNAT_acetyltran PF12746.7 AIO01325.1 - 0.14 11.7 0.0 0.23 11.0 0.0 1.3 1 0 0 1 1 1 0 GNAT acetyltransferase PD40 PF07676.12 AIO01325.1 - 0.15 12.1 0.3 26 4.9 0.0 3.3 3 1 0 3 3 3 0 WD40-like Beta Propeller Repeat Sugar_tr PF00083.24 AIO01326.1 - 1.3e-133 446.2 25.2 1.7e-133 445.9 25.2 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 AIO01326.1 - 1.5e-15 57.0 22.8 1.5e-15 57.0 22.8 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily YlmH_RBD PF17774.1 AIO01326.1 - 0.17 12.2 0.0 0.35 11.2 0.0 1.5 1 0 0 1 1 1 0 Putative RNA-binding domain in YlmH Autophagy_N PF03986.13 AIO01327.1 - 2.8e-26 92.1 0.2 4.4e-26 91.5 0.2 1.3 1 0 0 1 1 1 1 Autophagocytosis associated protein (Atg3), N-terminal domain Autophagy_act_C PF03987.15 AIO01327.1 - 3.9e-19 69.0 2.1 8.9e-19 67.8 2.1 1.6 1 0 0 1 1 1 1 Autophagocytosis associated protein, active-site domain Autophagy_C PF10381.9 AIO01327.1 - 1.2e-10 40.7 0.9 3e-10 39.4 0.9 1.7 1 0 0 1 1 1 1 Autophagocytosis associated protein C-terminal ABC_tran PF00005.27 AIO01329.1 - 4.6e-44 150.3 0.0 1.2e-20 74.4 0.0 3.1 3 0 0 3 3 2 2 ABC transporter AAA_21 PF13304.6 AIO01329.1 - 2.1e-16 60.6 1.4 0.00033 20.6 0.0 4.3 3 1 1 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 AIO01329.1 - 1.9e-10 40.5 3.1 0.00039 19.9 0.0 4.9 3 2 1 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 AIO01329.1 - 1.2e-07 31.4 0.2 0.012 15.3 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 AIO01329.1 - 1.2e-07 31.8 0.2 0.0089 15.9 0.0 2.7 2 0 0 2 2 2 2 RsgA GTPase AAA_22 PF13401.6 AIO01329.1 - 0.00028 21.2 0.0 0.41 10.9 0.0 2.8 2 0 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.23 AIO01329.1 - 0.00073 19.6 0.0 0.24 11.5 0.0 2.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase RNA_helicase PF00910.22 AIO01329.1 - 0.0011 19.3 0.0 0.95 9.9 0.0 2.6 2 0 0 2 2 2 1 RNA helicase AAA_23 PF13476.6 AIO01329.1 - 0.0013 19.3 17.4 0.1 13.1 0.1 4.7 5 0 0 5 5 4 2 AAA domain AAA PF00004.29 AIO01329.1 - 0.0015 19.0 0.1 1.9 8.9 0.0 3.4 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 AIO01329.1 - 0.0016 18.9 4.2 1.6 9.1 0.0 3.5 2 1 1 3 3 3 2 AAA ATPase domain AAA_28 PF13521.6 AIO01329.1 - 0.0017 18.7 3.9 0.099 12.9 0.0 2.9 3 0 0 3 3 2 1 AAA domain AAA_5 PF07728.14 AIO01329.1 - 0.0033 17.4 0.1 1.7 8.7 0.1 2.7 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_24 PF13479.6 AIO01329.1 - 0.0061 16.3 1.4 0.75 9.5 0.0 3.3 2 1 1 3 3 3 1 AAA domain AAA_14 PF13173.6 AIO01329.1 - 0.007 16.4 0.0 2.7 8.1 0.0 3.2 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 AIO01329.1 - 0.008 16.3 1.5 0.97 9.6 0.0 3.2 4 0 0 4 4 3 1 AAA domain ABC_tran_Xtn PF12848.7 AIO01329.1 - 0.01 15.8 2.4 0.01 15.8 2.4 3.5 3 0 0 3 3 3 0 ABC transporter Rad17 PF03215.15 AIO01329.1 - 0.014 15.3 0.0 4.6 7.1 0.0 2.5 2 0 0 2 2 2 0 Rad17 P-loop domain SbcCD_C PF13558.6 AIO01329.1 - 0.015 15.6 0.5 0.73 10.1 0.1 3.6 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit Nbl1_Borealin_N PF10444.9 AIO01329.1 - 0.043 13.5 0.2 0.15 11.7 0.2 2.0 1 0 0 1 1 1 0 Nbl1 / Borealin N terminal NTPase_1 PF03266.15 AIO01329.1 - 0.052 13.5 0.1 1.8 8.5 0.0 2.7 3 0 0 3 3 2 0 NTPase Mg_chelatase PF01078.21 AIO01329.1 - 0.073 12.4 0.0 4.8 6.5 0.0 2.6 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI NACHT PF05729.12 AIO01329.1 - 0.12 12.3 0.1 11 5.9 0.1 2.6 2 0 0 2 2 2 0 NACHT domain AAA_15 PF13175.6 AIO01329.1 - 0.45 10.2 0.0 0.45 10.2 0.0 4.5 5 1 1 6 6 5 0 AAA ATPase domain Cytidylate_kin PF02224.18 AIO01329.1 - 0.8 9.4 3.9 14 5.4 0.0 3.7 3 1 1 4 4 4 0 Cytidylate kinase AAA_18 PF13238.6 AIO01329.1 - 0.89 10.1 7.7 1.8 9.1 0.0 3.5 4 1 1 5 5 2 0 AAA domain HSP90 PF00183.18 AIO01330.1 - 7.2e-227 754.4 25.6 9.2e-227 754.0 25.6 1.1 1 0 0 1 1 1 1 Hsp90 protein HATPase_c PF02518.26 AIO01330.1 - 2.2e-17 63.6 0.1 4.4e-17 62.6 0.1 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 AIO01330.1 - 4.3e-11 42.8 0.3 1.8e-10 40.8 0.3 2.1 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Ribosomal_S20p PF01649.18 AIO01330.1 - 0.012 16.2 0.4 0.012 16.2 0.4 4.1 5 0 0 5 5 5 0 Ribosomal protein S20 LOH1CR12 PF10158.9 AIO01330.1 - 0.031 14.3 0.3 0.11 12.5 0.3 1.9 1 0 0 1 1 1 0 Tumour suppressor protein WD40 PF00400.32 AIO01331.1 - 2.5e-06 28.1 12.5 5.8e-05 23.8 0.0 6.0 7 0 0 7 7 7 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 AIO01331.1 - 0.00012 22.3 0.0 1.8 8.9 0.0 4.0 2 1 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain X PF00739.19 AIO01332.1 - 0.03 14.4 0.1 0.057 13.5 0.1 1.5 1 0 0 1 1 1 0 Trans-activation protein X Hydrolase_4 PF12146.8 AIO01334.1 - 3.1e-15 56.1 0.3 1.2e-09 37.8 0.4 2.2 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 AIO01334.1 - 1.7e-13 50.8 0.2 2.8e-09 37.0 0.4 2.2 1 1 1 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 AIO01334.1 - 2.5e-06 28.3 0.2 5.8e-06 27.1 0.2 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 AIO01334.1 - 2.1e-05 24.1 0.1 0.041 13.4 0.0 2.3 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_2 PF02230.16 AIO01334.1 - 0.00014 21.8 0.2 0.015 15.2 0.1 2.4 2 1 0 2 2 2 1 Phospholipase/Carboxylesterase FSH1 PF03959.13 AIO01334.1 - 0.022 14.4 0.0 0.042 13.5 0.0 1.4 1 0 0 1 1 1 0 Serine hydrolase (FSH1) Abhydrolase_3 PF07859.13 AIO01334.1 - 0.038 13.8 0.1 0.07 13.0 0.1 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold UPF0227 PF05728.12 AIO01334.1 - 0.053 13.5 0.1 8.8 6.2 0.0 2.3 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0227) Lipase_3 PF01764.25 AIO01334.1 - 0.15 12.0 0.0 0.28 11.0 0.0 1.5 1 0 0 1 1 1 0 Lipase (class 3) MutS_V PF00488.21 AIO01335.1 - 1.2e-71 240.7 0.0 2.1e-71 239.8 0.0 1.5 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 AIO01335.1 - 1.7e-27 96.9 0.4 1.7e-27 96.9 0.4 1.9 2 0 0 2 2 2 1 MutS domain III MutS_IV PF05190.18 AIO01335.1 - 2.6e-16 59.7 1.2 5.8e-16 58.6 1.2 1.6 1 0 0 1 1 1 1 MutS family domain IV R2K_3 PF14243.6 AIO01335.1 - 0.063 13.3 0.1 0.33 10.9 0.0 2.2 3 0 0 3 3 3 0 ATP-grasp domain, R2K clade family 3 AAA_29 PF13555.6 AIO01335.1 - 0.071 12.9 0.1 0.42 10.4 0.1 2.1 2 0 0 2 2 2 0 P-loop containing region of AAA domain MnmE_helical PF12631.7 AIO01335.1 - 0.34 11.0 2.7 0.89 9.7 2.0 2.0 2 1 0 2 2 2 0 MnmE helical domain FAD_binding_7 PF03441.14 AIO01341.1 - 1.2e-68 230.6 2.3 2.6e-68 229.5 2.1 1.6 2 0 0 2 2 2 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.18 AIO01341.1 - 2.6e-30 105.6 0.0 4.7e-30 104.7 0.0 1.4 1 0 0 1 1 1 1 DNA photolyase CALM_bind PF16025.5 AIO01342.1 - 0.31 11.5 4.8 1.5 9.4 4.6 2.3 1 1 0 1 1 1 0 Calcium-dependent calmodulin binding SET PF00856.28 AIO01345.1 - 5e-08 33.5 0.0 1.3e-07 32.1 0.0 1.8 2 0 0 2 2 2 1 SET domain ADH_N PF08240.12 AIO01346.1 - 1.4e-23 82.8 0.0 3.2e-23 81.7 0.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 AIO01346.1 - 9.1e-18 64.5 0.1 1.7e-17 63.6 0.0 1.5 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 AIO01346.1 - 4.8e-06 27.7 0.0 9.2e-06 26.7 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 AIO01346.1 - 2.1e-05 24.1 0.2 4.9e-05 22.9 0.2 1.7 1 1 0 1 1 1 1 Glucose dehydrogenase C-terminus LRR_4 PF12799.7 AIO01347.1 - 2.5e-24 84.9 0.1 7.1e-05 23.1 0.0 9.4 10 1 1 11 11 11 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 AIO01347.1 - 3.6e-11 42.7 5.4 0.00035 20.3 0.0 6.9 6 1 1 7 7 7 3 Leucine rich repeat LRR_6 PF13516.6 AIO01347.1 - 0.0046 16.9 2.5 1.3 9.3 0.0 5.4 5 0 0 5 5 5 1 Leucine Rich repeat LRR_1 PF00560.33 AIO01347.1 - 1.9 9.4 10.2 49 5.1 0.1 6.5 7 1 0 7 7 7 0 Leucine Rich Repeat NifU PF01106.17 AIO01349.1 - 4e-18 65.3 0.0 9.1e-18 64.2 0.0 1.6 1 0 0 1 1 1 1 NifU-like domain Nfu_N PF08712.11 AIO01349.1 - 3.1e-12 46.4 0.0 4.3e-10 39.5 0.0 2.4 2 0 0 2 2 2 2 Scaffold protein Nfu/NifU N terminal RtcB PF01139.17 AIO01351.1 - 2e-95 320.4 0.0 3.5e-95 319.6 0.0 1.4 1 1 0 1 1 1 1 tRNA-splicing ligase RtcB FYVE PF01363.21 AIO01352.1 - 0.31 11.2 19.0 2.3 8.4 19.3 1.9 1 1 0 1 1 1 0 FYVE zinc finger Nkap_C PF06047.11 AIO01354.1 - 6.2e-15 55.2 1.0 6.2e-15 55.2 1.0 2.0 2 0 0 2 2 2 1 NF-kappa-B-activating protein C-terminal domain BRE1 PF08647.11 AIO01356.1 - 1.5e-12 47.4 9.6 1.5e-12 47.4 9.6 11.3 3 2 9 12 12 12 5 BRE1 E3 ubiquitin ligase ATG16 PF08614.11 AIO01356.1 - 0.00046 20.5 18.1 0.00046 20.5 18.1 8.5 1 1 7 8 8 8 4 Autophagy protein 16 (ATG16) DUF3450 PF11932.8 AIO01356.1 - 0.0017 17.7 12.3 0.0017 17.7 12.3 9.5 2 2 7 9 9 9 2 Protein of unknown function (DUF3450) AAA_13 PF13166.6 AIO01356.1 - 0.004 15.9 15.3 0.004 15.9 15.3 6.6 1 1 4 6 6 6 3 AAA domain DUF745 PF05335.13 AIO01356.1 - 0.0055 16.4 11.8 0.0055 16.4 11.8 7.8 1 1 8 10 10 10 1 Protein of unknown function (DUF745) DUF4094 PF13334.6 AIO01356.1 - 0.007 16.8 3.9 0.007 16.8 3.9 9.1 1 1 5 7 7 7 1 Domain of unknown function (DUF4094) DUF724 PF05266.14 AIO01356.1 - 0.0099 15.7 3.7 0.0099 15.7 3.7 8.9 3 2 7 10 10 10 5 Protein of unknown function (DUF724) rve_3 PF13683.6 AIO01356.1 - 0.12 12.1 1.1 7.4 6.4 0.1 3.9 2 0 0 2 2 2 0 Integrase core domain APG6_N PF17675.1 AIO01356.1 - 2.8 8.5 148.2 0.14 12.7 15.5 9.5 2 2 7 10 10 10 0 Apg6 coiled-coil region IGR PF09597.10 AIO01357.1 - 1.7e-05 24.8 0.0 3.3e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 IGR protein motif TPR_12 PF13424.6 AIO01358.1 - 0.013 15.8 0.3 2.7 8.4 0.0 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.17 AIO01358.1 - 0.015 15.4 0.3 8.3 6.8 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.6 AIO01358.1 - 0.019 15.0 2.7 2.7 8.2 0.2 4.3 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_1 PF00515.28 AIO01358.1 - 0.071 13.0 0.0 16 5.5 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat IFT57 PF10498.9 AIO01360.1 - 5e-63 213.2 5.7 5.8e-63 213.0 5.7 1.0 1 0 0 1 1 1 1 Intra-flagellar transport protein 57 HBM PF16591.5 AIO01360.1 - 6.2e-05 22.5 8.3 0.00012 21.6 8.3 1.4 1 0 0 1 1 1 1 Helical bimodular sensor domain mRNA_stabil PF13929.6 AIO01360.1 - 0.0003 19.9 1.0 0.00083 18.4 0.9 1.8 1 1 0 1 1 1 1 mRNA stabilisation TPR_MLP1_2 PF07926.12 AIO01360.1 - 0.0011 19.1 8.5 0.075 13.1 0.5 2.5 2 0 0 2 2 2 2 TPR/MLP1/MLP2-like protein Apolipoprotein PF01442.18 AIO01360.1 - 0.0043 17.0 12.2 0.013 15.4 12.2 1.9 1 1 0 1 1 1 1 Apolipoprotein A1/A4/E domain CREPT PF16566.5 AIO01360.1 - 0.0045 17.2 5.2 0.0085 16.3 5.2 1.5 1 0 0 1 1 1 1 Cell-cycle alteration and expression-elevated protein in tumour KxDL PF10241.9 AIO01360.1 - 0.006 16.8 4.9 0.97 9.7 0.3 2.6 2 0 0 2 2 2 2 Uncharacterized conserved protein FRB_dom PF08771.11 AIO01360.1 - 0.011 16.1 1.0 0.027 14.9 0.9 1.7 1 1 0 1 1 1 0 FKBP12-rapamycin binding domain Spc7 PF08317.11 AIO01360.1 - 0.03 13.2 13.2 0.043 12.7 11.6 1.7 1 1 1 2 2 2 0 Spc7 kinetochore protein AAA_13 PF13166.6 AIO01360.1 - 0.041 12.5 5.5 0.05 12.3 5.5 1.1 1 0 0 1 1 1 0 AAA domain Laminin_II PF06009.12 AIO01360.1 - 0.043 13.8 10.6 0.51 10.3 0.5 2.4 1 1 1 2 2 2 0 Laminin Domain II CHDCT2 PF08074.11 AIO01360.1 - 0.045 13.9 5.2 0.35 11.0 2.2 2.2 1 1 1 2 2 2 0 CHDCT2 (NUC038) domain Phage_GPO PF05929.11 AIO01360.1 - 0.1 12.2 4.8 0.15 11.7 4.8 1.3 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase DUF745 PF05335.13 AIO01360.1 - 0.12 12.1 9.3 1.7 8.3 7.3 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF745) DUF1664 PF07889.12 AIO01360.1 - 0.18 11.9 10.9 0.98 9.5 3.6 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Exonuc_VII_L PF02601.15 AIO01360.1 - 0.23 11.0 10.9 0.42 10.1 10.9 1.5 1 1 0 1 1 1 0 Exonuclease VII, large subunit Fzo_mitofusin PF04799.13 AIO01360.1 - 0.37 10.3 9.1 0.38 10.3 7.8 1.7 1 1 0 1 1 1 0 fzo-like conserved region PRKG1_interact PF15898.5 AIO01360.1 - 0.9 10.5 11.0 0.7 10.8 8.6 2.0 2 1 0 2 2 1 0 cGMP-dependent protein kinase interacting domain DUF2203 PF09969.9 AIO01360.1 - 0.98 10.2 6.4 1.8 9.3 4.5 2.3 1 1 2 3 3 3 0 Uncharacterized conserved protein (DUF2203) Atg14 PF10186.9 AIO01360.1 - 1 8.4 12.7 1.7 7.6 11.5 1.8 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Ead_Ea22 PF13935.6 AIO01360.1 - 1.1 9.9 6.5 5.1 7.7 6.5 2.4 1 1 0 1 1 1 0 Ead/Ea22-like protein UPF0242 PF06785.11 AIO01360.1 - 1.2 9.3 10.0 1.9 8.6 10.0 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DUF883 PF05957.13 AIO01360.1 - 3.8 8.2 7.4 3.7 8.2 1.0 2.7 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) EF-hand_7 PF13499.6 AIO01362.1 - 0.0016 18.8 0.0 0.0022 18.4 0.0 1.2 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.32 AIO01362.1 - 0.012 15.2 0.0 0.16 11.6 0.0 2.4 1 1 1 2 2 2 0 EF hand EF-hand_6 PF13405.6 AIO01362.1 - 0.018 14.9 0.0 0.069 13.1 0.0 2.0 1 1 0 1 1 1 0 EF-hand domain HR1 PF02185.16 AIO01363.1 - 0.0013 18.8 1.7 0.0013 18.8 1.7 5.9 5 2 2 7 7 7 1 Hr1 repeat EF1_GNE PF00736.19 AIO01363.1 - 1.5 9.0 4.2 1.4e+02 2.8 1.0 3.9 3 0 0 3 3 3 0 EF-1 guanine nucleotide exchange domain WD40 PF00400.32 AIO01365.1 - 0.03 15.2 2.0 31 5.7 0.2 4.2 4 0 0 4 4 4 0 WD domain, G-beta repeat ERG4_ERG24 PF01222.17 AIO01366.1 - 3.5e-107 358.8 24.5 4.1e-107 358.6 24.5 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family TPR_2 PF07719.17 AIO01368.1 - 0.0079 16.2 5.2 0.7 10.2 0.0 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 AIO01368.1 - 0.0089 15.8 3.6 0.89 9.5 0.0 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat ANAPC3 PF12895.7 AIO01368.1 - 0.014 15.6 1.9 0.031 14.5 1.9 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.6 AIO01368.1 - 0.033 14.7 0.2 0.1 13.1 0.2 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat PTR2 PF00854.21 AIO01369.1 - 2.4e-32 112.2 0.6 4.1e-29 101.6 0.0 2.9 2 1 0 2 2 2 2 POT family MFS_1 PF07690.16 AIO01369.1 - 6.5e-07 28.6 37.3 6.4e-05 22.0 16.4 2.9 2 1 0 2 2 2 2 Major Facilitator Superfamily Ribosomal_L6e PF01159.19 AIO01370.1 - 1.6e-29 102.7 0.4 1.1e-28 100.0 0.4 2.0 1 1 0 1 1 1 1 Ribosomal protein L6e KOW PF00467.29 AIO01370.1 - 0.00035 20.4 0.0 0.0015 18.4 0.0 2.1 1 1 1 2 2 2 1 KOW motif ParE-like_toxin PF15781.5 AIO01370.1 - 0.6 10.1 3.1 2.8 8.0 3.1 2.0 1 1 0 1 1 1 0 ParE-like toxin of type II bacterial toxin-antitoxin system OAD_gamma PF04277.13 AIO01370.1 - 4.9 7.8 9.7 0.78 10.4 5.5 1.8 2 0 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain WD40 PF00400.32 AIO01371.1 - 1.6e-15 57.2 6.7 3.1e-05 24.6 0.2 4.8 4 0 0 4 4 4 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 AIO01371.1 - 0.00046 20.4 0.0 4.9 7.5 0.0 4.3 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain MCCD1 PF15707.5 AIO01372.1 - 0.014 15.8 0.6 0.027 14.9 0.6 1.4 1 0 0 1 1 1 0 Mitochondrial coiled-coil domain protein 1 Spc7_N PF15402.6 AIO01372.1 - 0.065 11.5 0.5 0.088 11.1 0.5 1.0 1 0 0 1 1 1 0 N-terminus of kinetochore NMS complex subunit Spc7 Neuropeptide_S PF14993.6 AIO01372.1 - 0.18 11.7 0.2 5.9 6.8 0.0 2.3 2 0 0 2 2 2 0 Neuropeptide S precursor protein Vitelline_membr PF10542.9 AIO01372.1 - 1.6 8.6 7.0 18 5.3 4.9 2.6 2 0 0 2 2 2 0 Vitelline membrane cysteine-rich region DUF2040 PF09745.9 AIO01374.1 - 0.0057 16.7 0.1 0.01 15.9 0.1 1.4 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 55 (DUF2040) CLZ PF16526.5 AIO01375.1 - 0.29 11.5 0.8 0.63 10.4 0.3 1.7 1 1 0 1 1 1 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Cyclin PF08613.11 AIO01376.1 - 2.1e-29 103.0 0.1 6e-29 101.5 0.1 1.9 1 1 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 AIO01376.1 - 0.0004 20.1 0.1 0.00067 19.4 0.1 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain NIF PF03031.18 AIO01377.1 - 3.1e-20 72.5 0.8 6.5e-18 65.0 0.1 2.5 2 0 0 2 2 2 2 NLI interacting factor-like phosphatase Tubulin_C PF03953.17 AIO01379.1 - 5.4e-42 142.9 0.1 8.1e-42 142.4 0.1 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin PF00091.25 AIO01379.1 - 7.4e-07 29.6 0.3 1.4e-06 28.7 0.1 1.6 2 0 0 2 2 2 1 Tubulin/FtsZ family, GTPase domain Oxidored_FMN PF00724.20 AIO01380.1 - 3e-73 247.0 0.0 4.6e-73 246.4 0.0 1.3 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Pyr_redox_2 PF07992.14 AIO01380.1 - 8.9e-22 77.7 2.4 7.6e-21 74.6 2.2 2.3 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 AIO01380.1 - 3.9e-09 36.6 0.2 2e-08 34.3 0.0 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 AIO01380.1 - 1.1e-07 32.3 3.6 0.0025 18.3 1.3 3.5 3 1 0 3 3 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 AIO01380.1 - 2.9e-07 30.1 1.8 0.0056 16.0 0.1 3.0 2 1 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 AIO01380.1 - 8.2e-07 28.5 0.2 0.0012 18.0 0.0 2.3 1 1 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) FAD_oxidored PF12831.7 AIO01380.1 - 8.8e-07 28.6 1.1 1.5e-06 27.8 1.1 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.14 AIO01380.1 - 1.8e-06 27.0 2.5 8.4e-06 24.7 0.5 2.4 1 1 1 2 2 2 1 HI0933-like protein FAD_binding_2 PF00890.24 AIO01380.1 - 1.7e-05 24.1 1.9 3.5e-05 23.1 1.9 1.5 1 0 0 1 1 1 1 FAD binding domain FMO-like PF00743.19 AIO01380.1 - 6.6e-05 21.5 0.1 3.1 6.1 0.0 3.1 3 0 0 3 3 3 3 Flavin-binding monooxygenase-like DAO PF01266.24 AIO01380.1 - 7.6e-05 22.4 1.1 7.6e-05 22.4 1.1 3.6 3 1 0 4 4 4 1 FAD dependent oxidoreductase GIDA PF01134.22 AIO01380.1 - 0.00011 21.5 2.7 0.0002 20.6 1.8 1.8 1 1 0 2 2 2 1 Glucose inhibited division protein A 3HCDH_N PF02737.18 AIO01380.1 - 0.00014 21.8 0.3 0.015 15.2 0.0 2.6 3 0 0 3 3 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_binding_3 PF01494.19 AIO01380.1 - 0.00019 20.8 1.4 0.0025 17.1 0.4 2.3 2 0 0 2 2 2 1 FAD binding domain NAD_binding_7 PF13241.6 AIO01380.1 - 0.00071 20.0 0.6 0.048 14.1 0.1 2.6 2 1 0 2 2 2 1 Putative NAD(P)-binding Thi4 PF01946.17 AIO01380.1 - 0.0034 16.7 0.4 0.01 15.1 0.2 1.8 2 0 0 2 2 2 1 Thi4 family NAD_Gly3P_dh_N PF01210.23 AIO01380.1 - 0.0041 17.1 0.2 0.14 12.1 0.0 2.4 2 0 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Amino_oxidase PF01593.24 AIO01380.1 - 0.011 15.1 0.2 0.02 14.2 0.2 1.4 1 0 0 1 1 1 0 Flavin containing amine oxidoreductase AlaDh_PNT_C PF01262.21 AIO01380.1 - 0.042 13.1 0.1 0.099 11.9 0.1 1.6 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_9 PF13454.6 AIO01380.1 - 0.048 13.7 4.5 0.44 10.5 0.3 3.1 4 0 0 4 4 4 0 FAD-NAD(P)-binding 2-Hacid_dh_C PF02826.19 AIO01380.1 - 0.11 11.9 0.0 8.3 5.7 0.0 2.3 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_2 PF03446.15 AIO01380.1 - 0.13 12.4 0.0 2 8.6 0.0 2.5 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase GFO_IDH_MocA PF01408.22 AIO01380.1 - 0.13 13.0 0.4 12 6.8 0.0 3.8 4 0 0 4 4 4 0 Oxidoreductase family, NAD-binding Rossmann fold Sacchrp_dh_NADP PF03435.18 AIO01380.1 - 0.15 12.3 1.1 22 5.3 0.0 3.2 3 0 0 3 3 3 0 Saccharopine dehydrogenase NADP binding domain Lycopene_cycl PF05834.12 AIO01380.1 - 0.21 10.6 1.6 0.31 10.0 0.3 1.9 2 0 0 2 2 2 0 Lycopene cyclase protein ApbA PF02558.16 AIO01380.1 - 0.25 11.0 1.4 15 5.2 0.8 2.8 2 1 0 2 2 2 0 Ketopantoate reductase PanE/ApbA End3 PF12761.7 AIO01382.1 - 0.075 13.2 0.6 0.21 11.7 0.1 1.9 2 0 0 2 2 2 0 Actin cytoskeleton-regulatory complex protein END3 TFR_dimer PF04253.15 AIO01382.1 - 0.089 12.9 0.2 1.1 9.4 0.0 2.3 2 0 0 2 2 2 0 Transferrin receptor-like dimerisation domain Sulfotransfer_4 PF17784.1 AIO01383.1 - 8.4e-44 150.0 0.0 1.6e-43 149.1 0.0 1.5 1 1 0 1 1 1 1 Sulfotransferase domain GAS2 PF02187.17 AIO01383.1 - 0.18 11.9 0.0 0.39 10.8 0.0 1.5 1 0 0 1 1 1 0 Growth-Arrest-Specific Protein 2 Domain zf-Tim10_DDP PF02953.15 AIO01386.1 - 0.001 18.7 1.3 0.08 12.6 0.2 2.4 2 0 0 2 2 2 2 Tim10/DDP family zinc finger DnaJ PF00226.31 AIO01387.1 - 1.7e-21 76.1 0.4 2.8e-21 75.4 0.4 1.4 1 0 0 1 1 1 1 DnaJ domain Mucin PF01456.17 AIO01387.1 - 0.97 9.4 7.3 4.3 7.3 6.8 2.4 1 1 1 2 2 2 0 Mucin-like glycoprotein Ribosomal_S3_C PF00189.20 AIO01389.1 - 1.4e-19 70.4 1.8 1.4e-19 70.4 1.8 2.2 2 1 1 3 3 3 1 Ribosomal protein S3, C-terminal domain KH_2 PF07650.17 AIO01389.1 - 1.8e-07 30.9 0.3 5e-07 29.5 0.3 1.7 2 0 0 2 2 2 1 KH domain IQ PF00612.27 AIO01390.1 - 0.047 13.5 0.0 0.17 11.7 0.0 2.1 1 0 0 1 1 1 0 IQ calmodulin-binding motif Rsc14 PF08586.10 AIO01391.1 - 0.85 10.5 3.2 13 6.7 0.2 2.4 1 1 1 2 2 2 0 RSC complex, Rsc14/Ldb7 subunit FIBP PF05427.11 AIO01392.1 - 6.8e-06 25.6 0.0 0.014 14.7 0.0 2.9 3 0 0 3 3 3 2 Acidic fibroblast growth factor binding (FIBP) WD40 PF00400.32 AIO01393.1 - 4.2e-06 27.4 3.4 0.21 12.5 0.0 6.6 6 0 0 6 6 6 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 AIO01393.1 - 9.9e-05 22.6 0.1 0.16 12.2 0.0 4.5 3 2 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain NAPRTase PF04095.16 AIO01394.1 - 1.5e-74 250.7 0.0 1.9e-74 250.3 0.0 1.1 1 0 0 1 1 1 1 Nicotinate phosphoribosyltransferase (NAPRTase) family NAPRTase_N PF17767.1 AIO01394.1 - 2.3e-37 128.2 0.1 4.1e-37 127.4 0.1 1.4 1 0 0 1 1 1 1 Nicotinate phosphoribosyltransferase (NAPRTase) N-terminal domain CCDC106 PF15794.5 AIO01395.1 - 3 7.5 11.4 5.3 6.7 11.4 1.3 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 Skp1 PF01466.19 AIO01396.1 - 1.4e-07 31.5 0.1 2.1e-07 31.0 0.1 1.3 1 0 0 1 1 1 1 Skp1 family, dimerisation domain Cation_ATPase_C PF00689.21 AIO01397.1 - 3.2e-39 134.5 5.8 3.2e-39 134.5 5.8 1.9 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 AIO01397.1 - 3.5e-30 104.8 2.4 3.5e-30 104.8 2.4 2.1 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.26 AIO01397.1 - 1.4e-10 41.8 0.1 0.072 13.4 0.0 3.3 3 0 0 3 3 3 3 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 AIO01397.1 - 1.5e-06 27.8 0.0 4.1e-06 26.4 0.0 1.8 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 AIO01397.1 - 6.1e-06 26.2 0.4 1.1e-05 25.4 0.4 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 AIO01397.1 - 1.3e-05 25.2 0.0 3e-05 24.0 0.0 1.6 1 0 0 1 1 1 1 Cation transport ATPase (P-type) PSP1 PF04468.12 AIO01398.1 - 9.7e-13 48.2 1.3 2.5e-12 46.9 1.3 1.8 1 1 0 1 1 1 1 PSP1 C-terminal conserved region PPTA PF01239.22 AIO01399.1 - 1.4e-26 91.4 16.3 1.4e-08 34.2 0.4 5.8 6 0 0 6 6 6 5 Protein prenyltransferase alpha subunit repeat Exostosin PF03016.15 AIO01399.1 - 0.056 12.6 0.7 0.14 11.4 0.6 1.7 1 1 0 1 1 1 0 Exostosin family OCRE PF17780.1 AIO01400.1 - 0.00021 21.2 7.2 0.00042 20.3 7.2 1.4 1 0 0 1 1 1 1 OCRE domain PPR_long PF17177.4 AIO01401.1 - 0.038 13.3 0.5 0.11 11.9 0.0 2.0 2 1 0 2 2 2 0 Pentacotripeptide-repeat region of PRORP Peptidase_S9 PF00326.21 AIO01402.1 - 0.007 15.9 0.0 0.011 15.2 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Voltage_CLC PF00654.20 AIO01403.1 - 8.1e-94 314.8 31.0 4.4e-93 312.3 26.9 2.2 2 0 0 2 2 2 2 Voltage gated chloride channel CBS PF00571.28 AIO01403.1 - 4.8e-13 49.3 1.0 7.1e-07 29.6 0.1 2.8 3 0 0 3 3 3 2 CBS domain Gly-zipper_YMGG PF13441.6 AIO01403.1 - 0.38 10.5 6.9 2.5 7.9 0.1 2.7 2 0 0 2 2 2 0 YMGG-like Gly-zipper YEATS PF03366.16 AIO01405.1 - 1.8e-08 34.2 0.0 3.4e-08 33.4 0.0 1.4 1 0 0 1 1 1 1 YEATS family LIF_OSM PF01291.17 AIO01405.1 - 0.14 12.3 0.0 0.27 11.4 0.0 1.5 1 0 0 1 1 1 0 LIF / OSM family PSK_trans_fac PF07704.11 AIO01405.1 - 2.5 8.9 5.3 4.6 8.1 0.7 2.9 3 0 0 3 3 3 0 Rv0623-like transcription factor Guanylate_kin PF00625.21 AIO01406.1 - 1.9e-48 164.6 0.0 2.3e-48 164.3 0.0 1.0 1 0 0 1 1 1 1 Guanylate kinase AAA_18 PF13238.6 AIO01406.1 - 1.2e-06 29.1 0.1 2.5e-06 28.1 0.1 1.6 1 1 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.23 AIO01406.1 - 1.7e-06 28.1 0.0 2.8e-06 27.4 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_33 PF13671.6 AIO01406.1 - 4.2e-05 23.7 0.0 0.00014 22.0 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.6 AIO01406.1 - 0.00056 20.2 0.2 0.0022 18.3 0.2 2.1 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.6 AIO01406.1 - 0.0011 19.4 0.2 0.28 11.6 0.0 2.8 2 1 0 2 2 2 1 AAA domain dNK PF01712.19 AIO01406.1 - 0.0028 17.5 0.0 0.18 11.7 0.0 2.1 2 0 0 2 2 2 1 Deoxynucleoside kinase RsgA_GTPase PF03193.16 AIO01406.1 - 0.0029 17.5 0.0 0.0054 16.6 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase ADK PF00406.22 AIO01406.1 - 0.0031 17.6 0.3 0.22 11.6 0.1 2.2 2 0 0 2 2 2 1 Adenylate kinase AAA_16 PF13191.6 AIO01406.1 - 0.0071 16.7 0.1 0.011 16.1 0.1 1.8 1 1 0 1 1 1 1 AAA ATPase domain Rad17 PF03215.15 AIO01406.1 - 0.041 13.8 0.0 0.061 13.2 0.0 1.5 1 0 0 1 1 1 0 Rad17 P-loop domain ABC_tran PF00005.27 AIO01406.1 - 0.076 13.5 0.1 0.17 12.4 0.1 2.0 1 1 0 1 1 1 0 ABC transporter CPT PF07931.12 AIO01406.1 - 0.11 12.3 0.0 0.16 11.8 0.0 1.3 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein zf-CW PF07496.15 AIO01407.1 - 1.8e-12 47.0 17.0 2.5e-08 33.8 7.8 3.9 3 0 0 3 3 3 3 CW-type Zinc Finger Yippee-Mis18 PF03226.14 AIO01408.1 - 0.0045 17.2 2.0 2.9 8.1 0.5 2.7 2 0 0 2 2 2 2 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly Nup88 PF10168.9 AIO01408.1 - 0.19 9.5 10.6 0.26 9.1 10.6 1.1 1 0 0 1 1 1 0 Nuclear pore component RIG-I_C-RD PF11648.8 AIO01408.1 - 2.5 8.4 4.5 2.1 8.6 0.0 2.4 2 0 0 2 2 2 0 C-terminal domain of RIG-I DUF16 PF01519.16 AIO01408.1 - 4.9 7.7 13.4 26 5.4 13.5 2.1 1 1 0 1 1 1 0 Protein of unknown function DUF16 DUF3395 PF11875.8 AIO01409.1 - 0.066 13.1 0.1 0.066 13.1 0.1 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3395) TIG PF01833.24 AIO01411.1 - 0.00028 20.9 0.5 0.0084 16.2 0.1 2.5 2 0 0 2 2 2 2 IPT/TIG domain TIG PF01833.24 AIO01412.1 - 1.9e-05 24.6 8.6 0.038 14.1 0.0 3.6 3 0 0 3 3 3 3 IPT/TIG domain FMN_bind PF04205.14 AIO01412.1 - 5.2 7.7 8.1 14 6.3 0.2 3.2 3 1 0 3 3 3 0 FMN-binding domain PUF PF00806.19 AIO01413.1 - 1.5e-50 166.1 6.5 3.3e-06 26.5 0.6 8.4 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat sCache_2 PF17200.4 AIO01413.1 - 0.062 13.1 0.0 51 3.7 0.0 3.8 4 0 0 4 4 4 0 Single Cache domain 2 Ax_dynein_light PF10211.9 AIO01416.1 - 2e-39 135.5 8.1 3e-39 134.9 8.1 1.2 1 0 0 1 1 1 1 Axonemal dynein light chain AAA PF00004.29 AIO01418.1 - 1.8e-14 54.3 0.0 7.5e-10 39.3 0.0 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 AIO01418.1 - 3.9e-06 26.9 0.0 1.7e-05 24.8 0.0 2.1 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 AIO01418.1 - 3.8e-05 24.1 0.7 0.0002 21.8 0.1 2.5 3 1 0 3 3 3 1 AAA ATPase domain AAA_18 PF13238.6 AIO01418.1 - 0.00074 20.1 0.0 0.0022 18.5 0.0 1.8 2 0 0 2 2 1 1 AAA domain AAA_22 PF13401.6 AIO01418.1 - 0.0028 18.0 0.1 0.019 15.2 0.0 2.4 2 1 0 2 2 2 1 AAA domain RuvB_N PF05496.12 AIO01418.1 - 0.0032 17.2 0.1 0.0086 15.8 0.0 1.7 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_24 PF13479.6 AIO01418.1 - 0.0062 16.3 0.0 0.012 15.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 AIO01418.1 - 0.007 16.5 0.1 0.032 14.4 0.0 2.1 2 1 0 2 2 2 1 AAA domain AAA_25 PF13481.6 AIO01418.1 - 0.0074 15.9 0.0 0.021 14.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain ATPase PF06745.13 AIO01418.1 - 0.019 14.3 0.0 0.1 11.9 0.0 2.1 2 0 0 2 2 2 0 KaiC IstB_IS21 PF01695.17 AIO01418.1 - 0.02 14.7 0.0 0.037 13.7 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein Mg_chelatase PF01078.21 AIO01418.1 - 0.036 13.4 0.0 0.094 12.1 0.0 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI DUF815 PF05673.13 AIO01418.1 - 0.065 12.4 0.0 0.15 11.2 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_19 PF13245.6 AIO01418.1 - 0.072 13.4 0.2 0.28 11.5 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 AIO01418.1 - 0.084 13.1 0.0 0.24 11.7 0.0 1.8 1 0 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 AIO01418.1 - 0.087 12.7 0.0 0.17 11.8 0.0 1.5 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea RNA_helicase PF00910.22 AIO01418.1 - 0.092 13.1 0.0 0.3 11.5 0.0 1.9 2 0 0 2 2 1 0 RNA helicase NB-ARC PF00931.22 AIO01418.1 - 0.13 11.4 0.0 0.24 10.5 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain AAA_30 PF13604.6 AIO01418.1 - 0.19 11.4 0.0 0.19 11.4 0.0 2.4 3 0 0 3 3 3 0 AAA domain PPR_2 PF13041.6 AIO01419.1 - 4.8e-05 23.5 0.2 0.0002 21.5 0.0 2.1 3 0 0 3 3 3 1 PPR repeat family PPR PF01535.20 AIO01419.1 - 0.0011 19.1 0.2 1.9 8.9 0.0 3.6 3 0 0 3 3 3 1 PPR repeat TPR_19 PF14559.6 AIO01419.1 - 0.0079 16.7 0.2 0.053 14.0 0.0 2.5 3 0 0 3 3 3 1 Tetratricopeptide repeat PPR_3 PF13812.6 AIO01419.1 - 0.079 13.0 0.1 0.4 10.8 0.0 2.0 2 0 0 2 2 2 0 Pentatricopeptide repeat domain Effector_1 PF04518.12 AIO01419.1 - 0.08 12.0 0.0 0.14 11.3 0.0 1.3 1 0 0 1 1 1 0 Effector from type III secretion system Nucleic_acid_bd PF13820.6 AIO01419.1 - 0.11 12.3 0.1 1.5 8.7 0.2 2.3 1 1 1 2 2 2 0 Putative nucleic acid-binding region GcrA PF07750.11 AIO01420.1 - 0.0031 17.9 0.8 0.014 15.8 0.1 2.1 2 0 0 2 2 2 1 GcrA cell cycle regulator F-box PF00646.33 AIO01420.1 - 0.049 13.5 0.6 0.093 12.6 0.1 1.8 2 0 0 2 2 2 0 F-box domain UIM PF02809.20 AIO01420.1 - 0.068 13.1 0.1 0.17 11.9 0.1 1.7 1 0 0 1 1 1 0 Ubiquitin interaction motif WD40 PF00400.32 AIO01421.1 - 6.5e-08 33.1 18.2 1.5e-07 31.9 0.1 5.4 6 1 0 6 6 6 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 AIO01421.1 - 1.5e-05 25.2 0.7 1.5 9.2 0.0 4.1 2 1 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain PQQ_3 PF13570.6 AIO01421.1 - 0.012 16.1 1.6 4.9 7.8 0.0 3.9 2 1 1 3 3 3 0 PQQ-like domain PQQ_2 PF13360.6 AIO01421.1 - 0.5 9.9 5.4 0.85 9.1 1.5 2.5 1 1 1 2 2 2 0 PQQ-like domain SlyX PF04102.12 AIO01421.1 - 4.2 8.1 5.4 3.4 8.3 1.4 2.5 2 1 0 2 2 2 0 SlyX WD40 PF00400.32 AIO01422.1 - 2.7e-07 31.2 13.3 0.00015 22.5 0.6 5.8 5 0 0 5 5 5 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 AIO01422.1 - 1.4e-05 25.3 0.1 3.5 8.0 0.0 3.8 4 0 0 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain PQQ_2 PF13360.6 AIO01422.1 - 0.05 13.2 2.2 1.2 8.6 0.2 3.0 1 1 0 2 2 2 0 PQQ-like domain COG2 PF06148.11 AIO01422.1 - 0.21 11.7 1.8 0.28 11.3 0.4 1.8 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF4226 PF10774.9 AIO01422.1 - 1.4 9.2 6.3 4.8 7.5 0.5 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4226) CFC PF09443.10 AIO01424.1 - 0.039 13.8 0.1 0.071 13.0 0.1 1.4 1 0 0 1 1 1 0 Cripto_Frl-1_Cryptic (CFC) EAR PF07897.11 AIO01426.1 - 0.096 12.3 0.2 0.19 11.4 0.2 1.5 1 0 0 1 1 1 0 Ethylene-responsive binding factor-associated repression Thioredoxin PF00085.20 AIO01427.1 - 1.6e-08 34.5 0.2 2.6e-08 33.8 0.2 1.3 1 0 0 1 1 1 1 Thioredoxin YfmQ PF10787.9 AIO01427.1 - 0.0071 16.1 0.2 0.0098 15.7 0.2 1.3 1 0 0 1 1 1 1 Uncharacterised protein from bacillus cereus group Thioredoxin_8 PF13905.6 AIO01427.1 - 0.0074 16.6 1.1 0.1 13.0 0.1 2.5 2 1 0 2 2 2 1 Thioredoxin-like AhpC-TSA PF00578.21 AIO01427.1 - 0.016 15.2 0.1 0.022 14.7 0.1 1.3 1 0 0 1 1 1 0 AhpC/TSA family Thioredoxin_2 PF13098.6 AIO01427.1 - 0.026 15.0 0.6 0.051 14.0 0.6 1.8 1 1 0 1 1 1 0 Thioredoxin-like domain Ribosomal_L29 PF00831.23 AIO01427.1 - 0.22 11.5 3.3 7.5 6.6 0.1 2.5 2 0 0 2 2 2 0 Ribosomal L29 protein MFS_1_like PF12832.7 AIO01428.1 - 1.1e-45 156.2 26.1 3.1e-45 154.7 26.1 1.7 1 1 0 1 1 1 1 MFS_1 like family MFS_1 PF07690.16 AIO01428.1 - 8.3e-21 74.3 54.5 5.1e-15 55.3 33.8 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Nuc_H_symport PF03825.16 AIO01428.1 - 1.3e-08 34.2 28.2 2.1e-08 33.6 28.2 1.3 1 0 0 1 1 1 1 Nucleoside H+ symporter LacY_symp PF01306.19 AIO01428.1 - 0.00019 20.4 23.9 0.00072 18.4 23.9 1.9 1 1 0 1 1 1 1 LacY proton/sugar symporter ABC1 PF03109.16 AIO01429.1 - 4.7e-28 97.7 0.0 9.5e-28 96.8 0.0 1.5 1 0 0 1 1 1 1 ABC1 family RIO1 PF01163.22 AIO01429.1 - 0.00042 20.0 0.0 0.00095 18.8 0.0 1.5 1 0 0 1 1 1 1 RIO1 family Pkinase PF00069.25 AIO01429.1 - 0.051 12.9 0.0 0.13 11.6 0.0 1.6 1 1 0 1 1 1 0 Protein kinase domain WaaY PF06176.11 AIO01429.1 - 0.069 12.8 0.0 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) NHase_alpha PF02979.16 AIO01429.1 - 0.14 11.4 0.1 0.41 9.9 0.1 1.8 1 1 0 1 1 1 0 Nitrile hydratase, alpha chain APH PF01636.23 AIO01429.1 - 0.32 10.9 4.9 2.4 8.0 0.1 3.2 3 1 1 4 4 4 0 Phosphotransferase enzyme family Cwf_Cwc_15 PF04889.12 AIO01430.1 - 1e-05 25.5 11.9 1.5e-05 24.8 11.9 1.4 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein Rotamase_3 PF13616.6 AIO01430.1 - 1.1 9.8 5.8 3.2 8.3 0.1 2.9 1 1 2 3 3 3 0 PPIC-type PPIASE domain DASH_Spc19 PF08287.11 AIO01430.1 - 3.9 7.4 10.5 0.63 9.9 6.9 1.7 2 0 0 2 2 2 0 Spc19 Ndc1_Nup PF09531.10 AIO01430.1 - 6 5.4 8.2 7.2 5.2 8.2 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Aminotran_1_2 PF00155.21 AIO01432.1 - 5.7e-51 173.8 0.0 6.5e-51 173.6 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 AIO01432.1 - 2.5e-06 26.3 0.2 3.7e-06 25.7 0.2 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.19 AIO01432.1 - 2.7e-05 23.3 0.1 5.5e-05 22.3 0.1 1.4 1 1 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 AIO01432.1 - 0.00015 21.2 0.1 0.00022 20.7 0.1 1.1 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Syntaxin PF00804.25 AIO01433.1 - 6.8e-09 35.7 15.4 1e-08 35.1 15.4 1.3 1 0 0 1 1 1 1 Syntaxin SNARE PF05739.19 AIO01433.1 - 6.3e-06 26.1 0.1 1.5e-05 24.9 0.1 1.6 1 0 0 1 1 1 1 SNARE domain Syntaxin_2 PF14523.6 AIO01433.1 - 0.028 14.8 2.7 0.028 14.8 2.7 2.3 2 0 0 2 2 2 0 Syntaxin-like protein Post_transc_reg PF13797.6 AIO01433.1 - 0.043 13.7 0.3 0.29 11.0 0.1 2.3 2 0 0 2 2 2 0 Post-transcriptional regulator MCPsignal PF00015.21 AIO01433.1 - 0.28 11.0 5.8 0.11 12.3 0.9 2.1 1 1 1 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain TBCC_N PF16752.5 AIO01433.1 - 1.5 9.3 14.5 0.28 11.6 4.7 2.9 1 1 2 3 3 3 0 Tubulin-specific chaperone C N-terminal domain DUF1664 PF07889.12 AIO01433.1 - 2.8 8.0 7.6 0.67 10.0 1.0 2.4 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) DUF2203 PF09969.9 AIO01433.1 - 3.3 8.4 9.4 7.5 7.3 1.3 3.1 1 1 2 3 3 3 0 Uncharacterized conserved protein (DUF2203) Rx_N PF18052.1 AIO01433.1 - 4.1 7.8 7.7 0.62 10.4 1.4 2.7 1 1 2 3 3 3 0 Rx N-terminal domain UPF0113 PF03657.13 AIO01434.1 - 1.1e-18 67.2 0.0 2.8e-18 66.0 0.0 1.6 2 0 0 2 2 2 1 UPF0113 PUA domain UPF0113_N PF17833.1 AIO01434.1 - 3.4e-18 66.0 0.1 5.4e-18 65.3 0.1 1.3 1 0 0 1 1 1 1 UPF0113 Pre-PUA domain DUF5317 PF17248.2 AIO01434.1 - 0.064 13.3 0.0 0.1 12.6 0.0 1.3 1 1 0 1 1 1 0 Family of unknown function (DUF5317) Baculo_LEF-11 PF06385.12 AIO01434.1 - 0.13 12.8 0.1 0.4 11.2 0.0 1.8 2 0 0 2 2 2 0 Baculovirus LEF-11 protein Complex1_LYR PF05347.15 AIO01435.1 - 5.2e-07 29.6 0.5 8.5e-07 28.9 0.5 1.3 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Suppressor_APC PF11414.8 AIO01436.1 - 0.58 10.2 3.8 2.6 8.2 0.1 2.9 2 1 0 2 2 2 0 Adenomatous polyposis coli tumour suppressor protein Pkinase PF00069.25 AIO01438.1 - 2e-64 217.5 0.0 2.7e-64 217.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 AIO01438.1 - 7.6e-32 110.6 0.0 9.9e-32 110.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 AIO01438.1 - 1.9e-06 27.4 0.3 3.7e-06 26.4 0.3 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 AIO01438.1 - 0.00037 19.5 0.3 0.00037 19.5 0.3 1.5 2 0 0 2 2 2 1 Haspin like kinase domain Kinase-like PF14531.6 AIO01438.1 - 0.0015 17.9 0.0 0.0024 17.2 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 AIO01438.1 - 0.005 15.7 0.7 0.013 14.3 0.0 1.8 2 0 0 2 2 2 1 Fungal protein kinase FTA2 PF13095.6 AIO01438.1 - 0.028 14.1 0.4 0.076 12.6 0.0 1.8 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 MRP-L28 PF09812.9 AIO01439.1 - 0.00023 21.3 0.1 0.00041 20.5 0.1 1.4 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L28 Hist_deacetyl PF00850.19 AIO01439.1 - 0.11 11.9 0.0 0.15 11.5 0.0 1.1 1 0 0 1 1 1 0 Histone deacetylase domain Pkinase PF00069.25 AIO01440.1 - 5.3e-49 167.0 0.0 4.7e-27 95.0 0.0 3.3 3 0 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.17 AIO01440.1 - 1.1e-27 97.0 0.6 3.3e-19 69.2 0.0 3.0 3 0 0 3 3 3 2 Protein tyrosine kinase FHA PF00498.26 AIO01440.1 - 4.9e-11 42.8 0.0 0.00028 21.2 0.0 3.0 3 0 0 3 3 3 2 FHA domain Kinase-like PF14531.6 AIO01440.1 - 1.6e-05 24.4 0.1 0.0011 18.3 0.1 2.2 2 0 0 2 2 2 1 Kinase-like Yop-YscD_cpl PF16697.5 AIO01440.1 - 2.8e-05 24.4 0.1 0.00036 20.8 0.0 2.4 2 0 0 2 2 2 1 Inner membrane component of T3SS, cytoplasmic domain RIO1 PF01163.22 AIO01440.1 - 0.0013 18.4 0.0 0.0024 17.5 0.0 1.3 1 0 0 1 1 1 1 RIO1 family APH PF01636.23 AIO01440.1 - 0.0094 15.9 0.0 0.18 11.7 0.0 2.6 1 1 1 2 2 2 1 Phosphotransferase enzyme family WD40 PF00400.32 AIO01441.1 - 2.9e-16 59.6 15.0 0.0007 20.4 0.2 6.6 6 0 0 6 6 6 3 WD domain, G-beta repeat Nup160 PF11715.8 AIO01441.1 - 0.00086 18.1 4.1 0.2 10.2 0.1 3.2 1 1 2 3 3 3 2 Nucleoporin Nup120/160 TMF_TATA_bd PF12325.8 AIO01441.1 - 0.0095 16.1 4.4 0.0095 16.1 4.4 3.1 1 1 2 3 3 3 1 TATA element modulatory factor 1 TATA binding Nucleoporin_N PF08801.11 AIO01441.1 - 0.024 13.4 0.2 0.38 9.4 0.1 2.3 1 1 1 2 2 2 0 Nup133 N terminal like AAA_13 PF13166.6 AIO01441.1 - 0.027 13.2 14.6 0.0062 15.2 10.9 1.6 1 1 1 2 2 2 0 AAA domain PQQ_3 PF13570.6 AIO01441.1 - 0.072 13.6 0.0 0.73 10.4 0.0 2.7 2 0 0 2 2 2 0 PQQ-like domain OmpH PF03938.14 AIO01441.1 - 0.086 13.2 25.9 0.055 13.8 9.3 2.2 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) ATG16 PF08614.11 AIO01441.1 - 0.14 12.4 30.6 0.33 11.2 26.0 2.8 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) DUF4457 PF14652.6 AIO01441.1 - 0.18 11.0 0.3 0.54 9.5 0.2 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4457) FUSC PF04632.12 AIO01441.1 - 0.18 10.3 16.6 0.3 9.5 16.6 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family TPR_MLP1_2 PF07926.12 AIO01441.1 - 0.86 9.7 27.4 0.35 10.9 11.8 2.3 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein JIP_LZII PF16471.5 AIO01441.1 - 0.98 9.6 16.1 0.77 10.0 4.1 3.2 3 0 0 3 3 3 0 JNK-interacting protein leucine zipper II BLOC1_2 PF10046.9 AIO01441.1 - 1.4 9.3 11.5 0.14 12.5 3.2 2.6 1 1 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Spc7 PF08317.11 AIO01441.1 - 2.5 6.9 23.8 12 4.7 23.2 1.9 1 1 1 2 2 2 0 Spc7 kinetochore protein Cep57_MT_bd PF06657.13 AIO01441.1 - 3.5 8.2 19.0 0.88 10.1 4.0 3.0 3 0 0 3 3 3 0 Centrosome microtubule-binding domain of Cep57 Tox-ODYAM1 PF15642.6 AIO01441.1 - 3.5 6.5 10.0 3.6 6.5 8.9 1.4 1 1 0 1 1 1 0 Toxin in Odyssella and Amoebophilus Sigma70_ner PF04546.13 AIO01441.1 - 7.1 6.4 14.8 11 5.9 14.8 1.2 1 0 0 1 1 1 0 Sigma-70, non-essential region Aa_trans PF01490.18 AIO01442.1 - 3.7e-54 184.0 22.3 4.3e-54 183.8 22.3 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 AIO01442.1 - 9.4e-08 31.5 13.2 9.4e-08 31.5 13.2 2.9 2 1 0 2 2 2 1 Tryptophan/tyrosine permease family RRM_1 PF00076.22 AIO01444.1 - 5.1e-08 32.6 0.0 7.3e-05 22.5 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Abhydro_lipase PF04083.16 AIO01444.1 - 0.093 12.3 0.1 0.25 10.9 0.1 1.8 1 0 0 1 1 1 0 Partial alpha/beta-hydrolase lipase region RRM_1 PF00076.22 AIO01445.1 - 2.1e-12 46.7 0.1 3e-08 33.3 0.1 2.3 1 1 1 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 AIO01445.1 - 0.00012 21.6 0.1 0.00018 21.1 0.1 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 AIO01445.1 - 0.0043 17.1 0.0 0.0077 16.3 0.0 1.6 1 1 0 1 1 1 1 RNA recognition motif DAO_C PF16901.5 AIO01445.1 - 0.02 14.8 0.0 0.034 14.0 0.0 1.4 1 0 0 1 1 1 0 C-terminal domain of alpha-glycerophosphate oxidase RRM_1 PF00076.22 AIO01446.1 - 1.7e-09 37.4 0.0 5.2e-09 35.8 0.0 1.8 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RNA_bind PF08675.11 AIO01446.1 - 0.0077 16.2 0.1 0.027 14.5 0.0 1.9 2 0 0 2 2 2 1 RNA binding domain Lipase_3 PF01764.25 AIO01447.1 - 3.4e-38 130.7 0.0 4.9e-38 130.2 0.0 1.2 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.7 AIO01447.1 - 3.8e-05 24.4 0.0 5.3e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF2974 PF11187.8 AIO01447.1 - 0.00016 21.3 0.3 0.0062 16.1 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF2974) Hydrolase_4 PF12146.8 AIO01447.1 - 0.00062 19.1 0.0 0.00097 18.5 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Esterase PF00756.20 AIO01447.1 - 0.0043 16.7 0.0 0.0066 16.1 0.0 1.2 1 0 0 1 1 1 1 Putative esterase Abhydrolase_5 PF12695.7 AIO01447.1 - 0.031 14.0 0.0 0.056 13.2 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family Thioesterase PF00975.20 AIO01447.1 - 0.04 14.0 0.0 0.065 13.3 0.0 1.3 1 0 0 1 1 1 0 Thioesterase domain PGAP1 PF07819.13 AIO01447.1 - 0.14 11.9 0.0 0.22 11.2 0.0 1.4 1 0 0 1 1 1 0 PGAP1-like protein DUF676 PF05057.14 AIO01447.1 - 0.16 11.4 0.0 0.25 10.8 0.0 1.2 1 0 0 1 1 1 0 Putative serine esterase (DUF676) RRM_1 PF00076.22 AIO01448.1 - 2.5e-16 59.2 0.0 3.8e-16 58.7 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 AIO01448.1 - 0.11 12.6 0.0 0.2 11.8 0.0 1.4 1 1 0 1 1 1 0 RNA recognition motif TPR_12 PF13424.6 AIO01449.1 - 3.2e-05 24.2 1.0 3.2e-05 24.2 1.0 5.5 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_2 PF07719.17 AIO01449.1 - 0.0056 16.7 16.4 0.49 10.6 0.2 6.9 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_1 PF00515.28 AIO01449.1 - 0.018 14.8 8.9 1.9 8.4 0.1 5.4 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_7 PF13176.6 AIO01449.1 - 0.026 14.5 1.2 11 6.3 0.0 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat ubiquitin PF00240.23 AIO01450.1 - 0.0035 17.1 0.1 0.56 10.0 0.1 2.7 2 1 0 2 2 2 2 Ubiquitin family Herpes_teg_N PF04843.12 AIO01450.1 - 0.1 12.3 0.0 0.2 11.3 0.0 1.4 1 0 0 1 1 1 0 Herpesvirus tegument protein, N-terminal conserved region TPR_14 PF13428.6 AIO01451.1 - 0.00035 21.1 2.5 0.33 11.9 0.0 4.5 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.6 AIO01451.1 - 0.11 13.0 0.1 3.2 8.3 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat PRA1 PF03208.19 AIO01452.1 - 1.1e-17 64.0 4.5 1.1e-17 64.0 4.5 1.5 1 1 0 1 1 1 1 PRA1 family protein TcpE PF12648.7 AIO01452.1 - 0.81 10.3 9.3 0.48 11.0 2.0 2.3 1 1 1 2 2 2 0 TcpE family PRA1 PF03208.19 AIO01453.1 - 2.3e-26 92.2 6.5 3.4e-26 91.6 6.5 1.2 1 0 0 1 1 1 1 PRA1 family protein GST_C PF00043.25 AIO01454.1 - 3.3e-14 52.9 0.0 5e-14 52.3 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 AIO01454.1 - 1.2e-08 35.2 0.0 2.2e-08 34.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 AIO01454.1 - 9.7e-07 28.7 0.0 2.3e-06 27.5 0.0 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 AIO01454.1 - 1.6e-06 28.2 0.0 2.5e-06 27.6 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 AIO01454.1 - 0.0047 17.3 0.0 0.0089 16.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain MetRS-N PF09635.10 AIO01454.1 - 0.031 14.8 0.0 0.093 13.3 0.0 1.7 2 0 0 2 2 2 0 MetRS-N binding domain DUF1204 PF06721.11 AIO01454.1 - 0.15 11.5 0.0 0.2 11.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1204) FlgN PF05130.12 AIO01455.1 - 0.068 13.7 0.5 1 9.9 0.1 2.3 2 0 0 2 2 2 0 FlgN protein ABC_tran_Xtn PF12848.7 AIO01455.1 - 0.093 12.8 0.0 0.2 11.7 0.0 1.4 1 0 0 1 1 1 0 ABC transporter TauE PF01925.19 AIO01456.1 - 5e-12 46.0 19.8 4.7e-06 26.4 8.8 2.2 2 0 0 2 2 2 2 Sulfite exporter TauE/SafE DivIC PF04977.15 AIO01456.1 - 0.0049 16.6 0.1 0.014 15.2 0.1 1.7 1 0 0 1 1 1 1 Septum formation initiator DUF2244 PF10003.9 AIO01456.1 - 0.023 14.4 0.5 0.023 14.4 0.5 2.8 2 0 0 2 2 2 0 Integral membrane protein (DUF2244) CcmD PF04995.14 AIO01456.1 - 0.8 9.8 3.8 9 6.5 0.0 2.9 3 0 0 3 3 3 0 Heme exporter protein D (CcmD) LapA_dom PF06305.11 AIO01456.1 - 2 8.3 7.0 2.3 8.1 0.3 3.1 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain RseC_MucC PF04246.12 AIO01456.1 - 2.9 7.9 10.1 0.16 12.0 0.6 2.8 2 1 0 2 2 2 0 Positive regulator of sigma(E), RseC/MucC Ribul_P_3_epim PF00834.19 AIO01457.1 - 1.4e-56 191.1 0.0 1.6e-56 190.8 0.0 1.0 1 0 0 1 1 1 1 Ribulose-phosphate 3 epimerase family OMPdecase PF00215.24 AIO01457.1 - 0.0032 17.1 0.3 0.0094 15.6 0.3 1.9 2 1 0 2 2 2 1 Orotidine 5'-phosphate decarboxylase / HUMPS family adh_short PF00106.25 AIO01457.1 - 0.12 11.9 0.8 0.25 10.8 0.3 1.7 2 0 0 2 2 2 0 short chain dehydrogenase adh_short_C2 PF13561.6 AIO01457.1 - 0.12 11.9 1.4 0.76 9.3 1.1 2.3 3 0 0 3 3 3 0 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 AIO01460.1 - 2.9e-31 108.5 0.0 3.7e-31 108.1 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 AIO01460.1 - 1.5e-22 80.4 0.0 2e-22 79.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 AIO01460.1 - 5.1e-08 33.0 0.0 7.8e-08 32.4 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 AIO01460.1 - 0.028 13.9 0.2 0.049 13.1 0.2 1.6 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family 3HCDH_N PF02737.18 AIO01460.1 - 0.036 14.0 0.0 0.078 12.9 0.0 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain HHH_5 PF14520.6 AIO01460.1 - 0.16 12.6 0.1 0.36 11.5 0.1 1.6 1 0 0 1 1 1 0 Helix-hairpin-helix domain Peptidase_M20 PF01546.28 AIO01462.1 - 2.4e-18 66.6 0.0 3.4e-18 66.1 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 AIO01462.1 - 9.4e-08 31.9 0.0 1.6e-07 31.2 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain HEAT PF02985.22 AIO01463.1 - 3.1e-09 36.3 13.8 9.9 6.7 0.1 9.9 10 0 0 10 10 10 4 HEAT repeat HEAT_2 PF13646.6 AIO01463.1 - 2.3e-05 24.7 0.0 0.16 12.4 0.0 4.4 2 1 1 3 3 3 2 HEAT repeats Cnd1 PF12717.7 AIO01463.1 - 0.0011 19.1 6.0 3.5 7.7 0.0 4.7 5 0 0 5 5 5 2 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.7 AIO01463.1 - 0.013 16.1 2.2 1.1 9.9 0.1 4.3 5 0 0 5 5 5 0 Vacuolar 14 Fab1-binding region Nipped-B_C PF12830.7 AIO01463.1 - 0.036 14.0 0.8 6.5 6.6 0.1 3.3 3 0 0 3 3 3 0 Sister chromatid cohesion C-terminus CLASP_N PF12348.8 AIO01463.1 - 0.037 13.6 3.7 0.33 10.5 0.8 3.7 4 1 0 4 4 4 0 CLASP N terminal Pro_isomerase PF00160.21 AIO01464.1 - 4.4e-45 153.8 0.1 5.1e-45 153.6 0.1 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD PHM7_cyt PF14703.6 AIO01465.1 - 0.0091 16.2 0.3 0.011 15.9 0.3 1.1 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter PIGA PF08288.12 AIO01468.1 - 6.7e-38 129.2 0.1 1.3e-37 128.2 0.1 1.5 1 0 0 1 1 1 1 PIGA (GPI anchor biosynthesis) Glyco_transf_4 PF13439.6 AIO01468.1 - 4.9e-28 98.3 0.3 1e-27 97.2 0.3 1.6 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glycos_transf_1 PF00534.20 AIO01468.1 - 1e-26 93.5 0.0 1.6e-26 92.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 AIO01468.1 - 1.2e-22 80.7 0.0 1.9e-22 80.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 AIO01468.1 - 4.2e-13 50.1 0.0 9e-13 49.0 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_trans_4_2 PF13477.6 AIO01468.1 - 0.0022 18.0 0.0 0.02 14.9 0.0 2.1 2 0 0 2 2 2 1 Glycosyl transferase 4-like Glyco_trans_2_3 PF13632.6 AIO01468.1 - 0.063 13.2 0.5 0.063 13.2 0.5 1.8 2 0 0 2 2 2 0 Glycosyl transferase family group 2 Glyco_trans_1_2 PF13524.6 AIO01468.1 - 0.15 12.4 0.0 0.39 11.1 0.0 1.7 1 0 0 1 1 1 0 Glycosyl transferases group 1 ThiI PF02568.14 AIO01469.1 - 2.1e-45 154.7 0.1 3.5e-45 154.0 0.1 1.3 1 0 0 1 1 1 1 Thiamine biosynthesis protein (ThiI) Aminotran_5 PF00266.19 AIO01469.1 - 4.9e-26 91.6 0.6 1.2e-12 47.5 0.0 2.2 1 1 1 2 2 2 2 Aminotransferase class-V tRNA_Me_trans PF03054.16 AIO01469.1 - 8.8e-05 21.4 0.0 0.00017 20.5 0.0 1.4 1 0 0 1 1 1 1 tRNA methyl transferase QueC PF06508.13 AIO01469.1 - 0.0022 17.5 0.6 0.035 13.6 0.0 2.6 3 0 0 3 3 3 1 Queuosine biosynthesis protein QueC DNA_pol_B PF00136.21 AIO01470.1 - 2.2e-137 458.5 0.0 3.1e-137 458.0 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.19 AIO01470.1 - 4.4e-73 246.3 0.0 8.6e-73 245.4 0.0 1.5 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.6 AIO01470.1 - 6.6e-18 65.0 9.1 1.6e-17 63.7 9.1 1.7 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta zinc-ribbons_6 PF07191.12 AIO01470.1 - 0.028 14.4 6.2 0.21 11.6 0.3 2.6 2 0 0 2 2 2 0 zinc-ribbons DNA_pol_B_2 PF03175.13 AIO01470.1 - 0.062 12.1 0.1 0.47 9.3 0.0 2.1 2 0 0 2 2 2 0 DNA polymerase type B, organellar and viral zf-RING-like PF08746.11 AIO01470.1 - 4 7.8 8.5 11 6.5 1.7 3.0 2 0 0 2 2 2 0 RING-like domain zf-ACC PF17848.1 AIO01470.1 - 8.7 6.5 6.4 2 8.5 0.2 2.5 2 0 0 2 2 2 0 Acetyl-coA carboxylase zinc finger domain SNF2_N PF00176.23 AIO01471.1 - 5.1e-70 235.9 0.9 2.6e-69 233.6 0.1 2.5 3 1 1 4 4 4 1 SNF2 family N-terminal domain Helicase_C PF00271.31 AIO01471.1 - 6e-20 71.6 0.0 2.7e-19 69.5 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 AIO01471.1 - 5.6e-09 36.2 0.0 1.6e-08 34.7 0.0 1.9 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SLIDE PF09111.10 AIO01471.1 - 9.8e-07 28.8 0.7 2.3e-06 27.6 0.7 1.6 1 0 0 1 1 1 1 SLIDE HAND PF09110.11 AIO01471.1 - 1.2e-05 26.0 2.5 4.5e-05 24.2 2.5 2.1 1 0 0 1 1 1 1 HAND DEAD PF00270.29 AIO01471.1 - 0.00011 22.1 0.0 0.00042 20.1 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase RRM_occluded PF16842.5 AIO01471.1 - 0.1 12.5 0.0 0.27 11.1 0.0 1.6 1 0 0 1 1 1 0 Occluded RNA-recognition motif Pkinase PF00069.25 AIO01472.1 - 1.1e-67 228.2 0.0 3.8e-67 226.4 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 AIO01472.1 - 2e-40 138.7 0.1 3.3e-40 138.0 0.1 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase EF-hand_7 PF13499.6 AIO01472.1 - 8.5e-16 58.2 0.7 3.6e-08 33.7 0.2 2.9 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 AIO01472.1 - 3.9e-11 41.9 0.8 0.011 15.7 0.0 5.4 3 1 1 4 4 4 2 EF-hand domain EF-hand_1 PF00036.32 AIO01472.1 - 4.4e-11 41.5 0.7 0.091 12.4 0.1 4.6 5 0 0 5 5 5 3 EF hand Kinase-like PF14531.6 AIO01472.1 - 1.8e-10 40.6 0.0 8.6e-10 38.4 0.0 1.9 1 1 1 2 2 2 1 Kinase-like EF-hand_8 PF13833.6 AIO01472.1 - 3.7e-08 33.1 1.7 0.00032 20.5 0.1 2.8 2 0 0 2 2 2 2 EF-hand domain pair RIO1 PF01163.22 AIO01472.1 - 1.5e-05 24.7 1.7 3.1e-05 23.7 1.7 1.4 1 0 0 1 1 1 1 RIO1 family Haspin_kinase PF12330.8 AIO01472.1 - 0.00079 18.5 0.1 0.0012 17.8 0.1 1.3 1 0 0 1 1 1 1 Haspin like kinase domain YrbL-PhoP_reg PF10707.9 AIO01472.1 - 0.0011 18.6 0.4 0.0021 17.6 0.4 1.4 1 0 0 1 1 1 1 PhoP regulatory network protein YrbL EF-hand_5 PF13202.6 AIO01472.1 - 0.0026 17.2 0.4 4 7.1 0.0 3.8 3 0 0 3 3 3 1 EF hand Kdo PF06293.14 AIO01472.1 - 0.0034 16.8 0.2 0.0069 15.8 0.2 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Crystallin PF00525.18 AIO01472.1 - 0.094 12.9 0.1 0.22 11.7 0.1 1.6 1 0 0 1 1 1 0 Alpha crystallin A chain, N terminal MYO10_CC PF16735.5 AIO01472.1 - 0.12 12.5 0.2 0.37 10.9 0.2 1.8 1 0 0 1 1 1 0 Unconventional myosin-X coiled coil domain TPR_12 PF13424.6 AIO01473.1 - 4.4e-22 78.2 10.3 6e-10 39.3 0.5 3.5 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.28 AIO01473.1 - 3.8e-12 45.5 8.5 0.033 14.0 0.2 5.3 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_2 PF07719.17 AIO01473.1 - 3.1e-07 30.0 13.1 0.26 11.5 0.4 5.7 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_8 PF13181.6 AIO01473.1 - 1e-06 28.4 2.7 0.98 9.8 0.0 4.7 4 0 0 4 4 4 2 Tetratricopeptide repeat ANAPC5 PF12862.7 AIO01473.1 - 4.5e-05 23.4 4.3 0.14 12.3 0.1 3.1 1 1 2 3 3 3 2 Anaphase-promoting complex subunit 5 TPR_MalT PF17874.1 AIO01473.1 - 0.00019 20.9 2.7 0.00019 20.9 2.7 2.2 2 1 0 2 2 2 1 MalT-like TPR region TPR_9 PF13371.6 AIO01473.1 - 0.00023 21.2 4.6 0.39 10.9 0.0 3.8 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.6 AIO01473.1 - 0.00058 19.7 9.1 4.6 7.5 0.0 5.6 6 0 0 6 6 6 1 Tetratricopeptide repeat RPN7 PF10602.9 AIO01473.1 - 0.022 14.4 2.2 3.6 7.3 0.2 3.2 1 1 0 2 2 2 0 26S proteasome subunit RPN7 TPR_21 PF09976.9 AIO01473.1 - 0.037 13.8 0.2 0.088 12.5 0.2 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat-like domain TPR_16 PF13432.6 AIO01473.1 - 0.11 13.1 2.4 16 6.3 0.0 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat MIF PF01187.18 AIO01475.1 - 5.7e-05 23.4 0.0 6e-05 23.3 0.0 1.0 1 0 0 1 1 1 1 Macrophage migration inhibitory factor (MIF) OTT_1508_deam PF14441.6 AIO01476.1 - 0.0003 20.7 0.7 0.00051 20.0 0.1 1.8 2 0 0 2 2 2 1 OTT_1508-like deaminase dCMP_cyt_deam_1 PF00383.23 AIO01476.1 - 0.12 12.3 0.1 0.19 11.6 0.1 1.3 1 0 0 1 1 1 0 Cytidine and deoxycytidylate deaminase zinc-binding region LisH PF08513.11 AIO01477.1 - 0.048 13.6 0.1 0.16 12.0 0.1 2.0 2 0 0 2 2 2 0 LisH DDT PF02791.17 AIO01477.1 - 0.49 10.7 3.9 31 5.0 0.3 3.8 3 0 0 3 3 3 0 DDT domain DOT1 PF08123.13 AIO01478.1 - 2.3e-15 56.7 0.1 3.3e-15 56.2 0.1 1.1 1 0 0 1 1 1 1 Histone methylation protein DOT1 Methyltransf_31 PF13847.6 AIO01478.1 - 7.7e-05 22.5 0.0 0.00011 22.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.17 AIO01478.1 - 0.0034 16.9 0.2 0.056 12.9 0.0 2.2 1 1 0 2 2 2 1 Putative methyltransferase Methyltransf_23 PF13489.6 AIO01478.1 - 0.034 14.0 0.0 0.058 13.2 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.12 AIO01478.1 - 0.04 14.7 0.0 0.091 13.5 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_25 PF13649.6 AIO01478.1 - 0.048 14.4 0.0 0.084 13.6 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_18 PF12847.7 AIO01478.1 - 0.099 12.6 0.0 0.16 11.9 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Glyco_hydro_10 PF00331.20 AIO01478.1 - 0.1 11.7 0.0 0.14 11.3 0.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 10 DER1 PF04511.15 AIO01479.1 - 1.1e-30 107.0 10.9 1.4e-30 106.7 10.9 1.0 1 0 0 1 1 1 1 Der1-like family Oleosin PF01277.17 AIO01479.1 - 0.0021 17.8 0.1 0.0021 17.8 0.1 2.0 2 1 0 2 2 2 1 Oleosin Pkinase PF00069.25 AIO01482.1 - 1.2e-48 165.7 0.0 1.6e-48 165.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 AIO01482.1 - 2.7e-22 79.3 0.0 4.1e-22 78.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 AIO01482.1 - 0.01 15.8 0.0 0.03 14.3 0.0 1.7 1 1 0 1 1 1 0 Phosphotransferase enzyme family ABC1 PF03109.16 AIO01482.1 - 0.057 13.6 0.0 0.14 12.3 0.0 1.7 1 0 0 1 1 1 0 ABC1 family Pox_ser-thr_kin PF05445.11 AIO01482.1 - 0.061 12.3 0.0 0.1 11.6 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Ras PF00071.22 AIO01483.1 - 2.9e-49 166.8 0.0 3.4e-49 166.5 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 AIO01483.1 - 5.9e-33 113.6 0.0 9.8e-33 112.9 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 AIO01483.1 - 8.1e-16 58.0 0.0 9.8e-16 57.7 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 AIO01483.1 - 6.4e-06 25.7 0.0 9.4e-06 25.1 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 AIO01483.1 - 2.7e-05 24.1 0.5 0.023 14.6 0.5 3.1 2 1 1 3 3 3 1 RsgA GTPase MMR_HSR1 PF01926.23 AIO01483.1 - 4.3e-05 23.6 0.0 8.7e-05 22.6 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_24 PF13479.6 AIO01483.1 - 0.00073 19.3 0.1 0.011 15.5 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 AIO01483.1 - 0.0041 17.5 0.1 0.0068 16.8 0.1 1.7 1 1 0 1 1 1 1 AAA ATPase domain MCM PF00493.23 AIO01483.1 - 0.012 14.8 0.0 0.034 13.2 0.0 1.7 2 0 0 2 2 2 0 MCM P-loop domain GTP_EFTU PF00009.27 AIO01483.1 - 0.013 15.1 0.1 0.082 12.4 0.1 2.2 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain DAP3 PF10236.9 AIO01483.1 - 0.016 14.4 0.1 0.026 13.7 0.1 1.3 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 AAA_29 PF13555.6 AIO01483.1 - 0.017 14.8 1.5 0.049 13.4 1.2 2.0 2 0 0 2 2 2 0 P-loop containing region of AAA domain ATP_bind_1 PF03029.17 AIO01483.1 - 0.033 14.0 0.2 0.12 12.1 0.0 1.9 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein ABC_tran PF00005.27 AIO01483.1 - 0.052 14.1 0.2 0.12 12.9 0.0 1.7 2 0 0 2 2 2 0 ABC transporter AAA_25 PF13481.6 AIO01483.1 - 0.065 12.8 0.5 0.46 10.0 0.5 2.1 1 1 0 1 1 1 0 AAA domain AAA_7 PF12775.7 AIO01483.1 - 0.066 12.7 0.1 0.18 11.3 0.1 1.7 2 0 0 2 2 2 0 P-loop containing dynein motor region SRPRB PF09439.10 AIO01483.1 - 0.1 12.0 0.0 0.15 11.5 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit TniB PF05621.11 AIO01483.1 - 0.11 11.8 0.0 0.79 9.1 0.0 2.1 2 0 0 2 2 2 0 Bacterial TniB protein DUF815 PF05673.13 AIO01483.1 - 0.13 11.4 0.3 0.31 10.1 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF815) YTH PF04146.15 AIO01483.1 - 0.14 12.1 0.0 0.16 11.9 0.0 1.2 1 0 0 1 1 1 0 YT521-B-like domain AAA_23 PF13476.6 AIO01483.1 - 0.14 12.6 0.0 0.18 12.2 0.0 1.3 1 1 0 1 1 1 0 AAA domain G-alpha PF00503.20 AIO01483.1 - 0.14 11.2 0.5 2.5 7.2 0.2 2.2 2 0 0 2 2 2 0 G-protein alpha subunit AAA_5 PF07728.14 AIO01483.1 - 0.15 12.1 0.1 0.51 10.3 0.1 1.9 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) DUF2520 PF10728.9 AIO01484.1 - 0.11 12.2 1.0 0.22 11.3 0.2 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF2520) ABC_membrane_2 PF06472.15 AIO01485.1 - 1.2e-66 224.9 0.4 1.6e-66 224.5 0.4 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 ABC_tran PF00005.27 AIO01485.1 - 3.9e-18 66.3 0.0 7.5e-18 65.4 0.0 1.5 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 AIO01485.1 - 0.0039 16.7 0.0 0.24 10.8 0.0 2.6 3 0 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 AIO01485.1 - 0.0039 17.0 0.0 0.0071 16.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system ABC_membrane PF00664.23 AIO01485.1 - 0.01 15.5 0.4 0.01 15.5 0.4 1.6 2 0 0 2 2 2 0 ABC transporter transmembrane region NACHT PF05729.12 AIO01485.1 - 0.014 15.3 0.1 0.25 11.3 0.0 2.7 3 0 0 3 3 3 0 NACHT domain AAA_29 PF13555.6 AIO01485.1 - 0.018 14.8 0.1 0.049 13.4 0.1 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF3584 PF12128.8 AIO01485.1 - 0.021 12.4 0.5 0.037 11.6 0.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) AAA_30 PF13604.6 AIO01485.1 - 0.021 14.5 0.0 0.044 13.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 AIO01485.1 - 0.029 14.9 0.0 0.059 13.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 AIO01485.1 - 0.069 12.5 0.2 0.21 10.9 0.0 1.8 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_22 PF13401.6 AIO01485.1 - 0.081 13.2 0.6 2.5 8.4 0.0 3.0 3 0 0 3 3 3 0 AAA domain PgaD PF13994.6 AIO01485.1 - 0.1 12.7 0.0 0.31 11.1 0.0 1.8 2 0 0 2 2 1 0 PgaD-like protein DUF87 PF01935.17 AIO01485.1 - 0.1 12.7 0.2 0.21 11.7 0.2 1.4 1 0 0 1 1 1 0 Helicase HerA, central domain FtsK_SpoIIIE PF01580.18 AIO01485.1 - 0.12 11.7 0.0 0.24 10.7 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family NOG1_N PF17835.1 AIO01486.1 - 7.9e-53 178.7 0.3 1.5e-52 177.8 0.3 1.5 1 0 0 1 1 1 1 NOG1 N-terminal helical domain NOG1 PF06858.14 AIO01486.1 - 6.7e-28 96.2 0.0 2e-27 94.8 0.0 1.8 2 0 0 2 2 2 1 Nucleolar GTP-binding protein 1 (NOG1) NOGCT PF08155.11 AIO01486.1 - 1.8e-21 75.9 6.2 5.2e-21 74.4 6.2 1.9 1 0 0 1 1 1 1 NOGCT (NUC087) domain MMR_HSR1 PF01926.23 AIO01486.1 - 2.7e-17 62.9 0.0 5.5e-17 61.9 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 AIO01486.1 - 7.7e-10 38.5 0.0 1.5e-09 37.6 0.0 1.5 1 0 0 1 1 1 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 AIO01486.1 - 0.0004 20.3 0.0 1.5 8.7 0.0 2.7 2 1 0 2 2 2 2 RsgA GTPase AIG1 PF04548.16 AIO01486.1 - 0.0074 15.6 0.1 0.022 14.1 0.0 1.8 2 0 0 2 2 2 1 AIG1 family Ras PF00071.22 AIO01486.1 - 0.015 14.9 0.1 0.042 13.4 0.1 1.7 1 1 0 1 1 1 0 Ras family Dynamin_N PF00350.23 AIO01486.1 - 0.082 13.0 0.1 5.7 7.0 0.0 2.6 1 1 1 2 2 2 0 Dynamin family IQ PF00612.27 AIO01487.1 - 0.0002 20.9 0.2 0.00069 19.2 0.2 1.9 1 0 0 1 1 1 1 IQ calmodulin-binding motif FOP_dimer PF09398.10 AIO01489.1 - 6.1e-12 45.6 0.1 1.3e-11 44.6 0.0 1.5 2 0 0 2 2 2 1 FOP N terminal dimerisation domain LisH_2 PF16045.5 AIO01489.1 - 1.6e-05 23.8 0.0 2.6e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 LisH LisH PF08513.11 AIO01489.1 - 0.012 15.5 0.1 0.024 14.6 0.1 1.5 1 0 0 1 1 1 0 LisH Snf7 PF03357.21 AIO01490.1 - 9.1e-12 44.9 9.6 9.1e-12 44.9 9.6 2.0 1 1 1 2 2 2 2 Snf7 LAP2alpha PF11560.8 AIO01490.1 - 0.041 13.3 0.8 0.06 12.8 0.5 1.4 1 1 0 1 1 1 0 Lamina-associated polypeptide 2 alpha Ist1 PF03398.14 AIO01490.1 - 0.051 13.5 4.3 0.13 12.2 4.3 1.7 1 1 0 1 1 1 0 Regulator of Vps4 activity in the MVB pathway DUF1463 PF07316.11 AIO01490.1 - 0.25 11.2 1.6 14 5.5 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1463) CAF1C_H4-bd PF12265.8 AIO01491.1 - 5.5e-12 45.8 0.0 1.3e-11 44.6 0.0 1.6 1 0 0 1 1 1 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex DUF2457 PF10446.9 AIO01491.1 - 0.0022 17.2 20.9 0.0022 17.2 20.9 2.2 1 1 1 2 2 2 1 Protein of unknown function (DUF2457) WD40 PF00400.32 AIO01491.1 - 0.25 12.3 0.0 0.25 12.3 0.0 4.4 5 0 0 5 5 5 0 WD domain, G-beta repeat Utp14 PF04615.13 AIO01491.1 - 4.1 5.9 18.3 4 5.9 12.5 2.0 2 0 0 2 2 2 0 Utp14 protein SDA1 PF05285.12 AIO01491.1 - 6.4 6.1 25.7 7.8 5.8 16.8 2.2 2 0 0 2 2 2 0 SDA1 Pho88 PF10032.9 AIO01492.1 - 2.2e-26 92.2 0.0 2.7e-26 92.0 0.0 1.0 1 0 0 1 1 1 1 Phosphate transport (Pho88) Pribosyltran_N PF13793.6 AIO01494.1 - 3.4e-40 136.6 0.1 1.2e-39 134.9 0.0 1.9 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.6 AIO01494.1 - 1.4e-22 80.7 0.7 9.2e-22 78.0 0.3 2.1 1 1 1 2 2 2 1 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.27 AIO01494.1 - 2.5e-17 62.8 0.2 5.5e-17 61.7 0.2 1.5 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.6 AIO01494.1 - 0.045 13.2 0.1 0.081 12.4 0.1 1.4 1 0 0 1 1 1 0 Uracil phosphoribosyltransferase HTH_CodY PF08222.11 AIO01494.1 - 0.096 12.3 0.2 0.22 11.1 0.2 1.6 1 0 0 1 1 1 0 CodY helix-turn-helix domain zn-ribbon_14 PF16503.5 AIO01494.1 - 0.12 11.9 0.4 0.31 10.6 0.4 1.7 1 0 0 1 1 1 0 Zinc-ribbon CxC3 PF18804.1 AIO01494.1 - 0.17 11.8 0.5 0.37 10.6 0.2 1.7 2 0 0 2 2 2 0 CxC3 like cysteine cluster associated with KDZ transposases MHYT PF03707.16 AIO01495.1 - 1.5 9.0 9.1 0.77 10.0 1.3 3.0 2 0 0 2 2 2 0 Bacterial signalling protein N terminal repeat PRORP PF16953.5 AIO01496.1 - 8.7e-17 61.4 0.2 2.3e-06 27.3 0.3 4.5 5 0 0 5 5 5 4 Protein-only RNase P PPR_long PF17177.4 AIO01496.1 - 5.2e-11 42.3 0.1 8.5e-11 41.6 0.1 1.2 1 0 0 1 1 1 1 Pentacotripeptide-repeat region of PRORP Ribosomal_L37e PF01907.19 AIO01497.1 - 1.4e-24 86.0 8.2 2.2e-24 85.4 8.2 1.3 1 0 0 1 1 1 1 Ribosomal protein L37e Pkinase PF00069.25 AIO01500.1 - 2.8e-60 203.9 0.0 3.6e-60 203.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 AIO01500.1 - 3.2e-37 128.2 0.0 4.2e-37 127.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 AIO01500.1 - 1.8e-07 30.8 0.0 2.5e-07 30.3 0.0 1.2 1 0 0 1 1 1 1 Kinase-like PH PF00169.29 AIO01500.1 - 2.3e-07 31.3 0.0 7.3e-07 29.7 0.0 1.8 2 0 0 2 2 2 1 PH domain Pkinase_fungal PF17667.1 AIO01500.1 - 0.019 13.8 0.0 0.022 13.5 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase PH_11 PF15413.6 AIO01500.1 - 0.051 14.0 0.1 0.14 12.6 0.1 1.9 1 1 0 1 1 1 0 Pleckstrin homology domain DUF1636 PF07845.11 AIO01500.1 - 0.071 13.6 0.0 0.14 12.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1636) PH_9 PF15410.6 AIO01500.1 - 0.14 12.5 0.0 6.2 7.2 0.0 2.5 1 1 0 1 1 1 0 Pleckstrin homology domain PEN-2 PF10251.9 AIO01502.1 - 6.3e-08 32.9 7.3 1e-07 32.3 7.3 1.5 1 1 0 1 1 1 1 Presenilin enhancer-2 subunit of gamma secretase Peptidase_C2 PF00648.21 AIO01503.1 - 6.3e-34 117.3 0.0 1e-33 116.6 0.0 1.2 1 0 0 1 1 1 1 Calpain family cysteine protease Calpain_III PF01067.22 AIO01503.1 - 1.3e-09 38.4 0.0 0.0003 21.1 0.0 3.6 3 0 0 3 3 3 2 Calpain large subunit, domain III MIT PF04212.18 AIO01503.1 - 3.8e-07 30.1 0.7 1e-06 28.7 0.5 1.8 2 0 0 2 2 2 1 MIT (microtubule interacting and transport) domain TPR_2 PF07719.17 AIO01503.1 - 0.16 12.2 0.2 2.8 8.3 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat Acyl-CoA_dh_1 PF00441.24 AIO01505.1 - 0.032 14.5 1.6 0.081 13.1 1.6 1.7 1 0 0 1 1 1 0 Acyl-CoA dehydrogenase, C-terminal domain Nup84_Nup100 PF04121.13 AIO01506.1 - 3.2e-08 32.2 0.8 0.00082 17.6 0.0 2.9 2 1 1 3 3 3 2 Nuclear pore protein 84 / 107 Peptidase_M23 PF01551.22 AIO01506.1 - 0.05 13.8 0.0 0.55 10.5 0.0 2.3 2 0 0 2 2 2 0 Peptidase family M23 DUF383 PF04063.14 AIO01507.1 - 0.014 15.1 0.1 0.042 13.5 0.0 1.8 2 1 0 2 2 2 0 Domain of unknown function (DUF383) HEAT_2 PF13646.6 AIO01507.1 - 0.03 14.7 0.5 27 5.2 0.0 3.9 4 0 0 4 4 4 0 HEAT repeats HEAT PF02985.22 AIO01507.1 - 0.066 13.5 0.0 3.6 8.1 0.0 3.5 3 0 0 3 3 3 0 HEAT repeat Pkinase PF00069.25 AIO01509.1 - 2e-46 158.5 0.0 3.2e-35 121.8 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 AIO01509.1 - 2e-26 92.8 0.1 7.9e-16 58.1 0.0 3.1 3 0 0 3 3 3 3 Protein tyrosine kinase E1-E2_ATPase PF00122.20 AIO01511.1 - 7.3e-46 156.0 0.4 7.3e-46 156.0 0.4 2.2 2 0 0 2 2 2 1 E1-E2 ATPase HMA PF00403.26 AIO01511.1 - 3.7e-35 120.2 0.4 2.3e-11 43.9 0.0 3.6 3 0 0 3 3 3 3 Heavy-metal-associated domain Hydrolase PF00702.26 AIO01511.1 - 6.5e-32 111.5 0.3 1.4e-31 110.5 0.3 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 AIO01511.1 - 8.4e-06 25.7 0.3 0.00013 21.8 0.1 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase CoA_binding_2 PF13380.6 AIO01511.1 - 0.00086 19.8 0.3 0.003 18.1 0.3 2.0 1 0 0 1 1 1 1 CoA binding domain cpYpsA PF12694.7 AIO01511.1 - 0.011 15.5 0.0 0.029 14.2 0.0 1.7 1 1 0 1 1 1 0 Circularly permutated YpsA SLOG family TctB PF07331.11 AIO01511.1 - 0.023 15.0 0.7 0.023 15.0 0.7 3.4 2 1 1 3 3 3 0 Tripartite tricarboxylate transporter TctB family Tox-PL-2 PF15643.6 AIO01511.1 - 0.032 14.4 0.4 18 5.5 0.0 3.3 3 0 0 3 3 3 0 Papain fold toxin 2 HAD PF12710.7 AIO01511.1 - 0.093 13.1 0.1 0.24 11.8 0.1 1.7 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase ProQ_C PF17516.2 AIO01511.1 - 0.15 11.5 1.5 0.98 8.9 0.0 3.0 3 0 0 3 3 3 0 ProQ C-terminal domain His_Phos_1 PF00300.22 AIO01512.1 - 8.5e-29 100.6 0.1 7.3e-21 74.8 0.0 2.2 2 0 0 2 2 2 2 Histidine phosphatase superfamily (branch 1) His_Phos_1 PF00300.22 AIO01513.1 - 5.4e-17 62.1 0.1 2.5e-09 37.1 0.0 2.5 3 0 0 3 3 3 2 Histidine phosphatase superfamily (branch 1) zf-HIT PF04438.16 AIO01514.1 - 5.3e-07 29.4 14.6 1.4e-06 28.1 14.6 1.7 1 0 0 1 1 1 1 HIT zinc finger zf-B_box PF00643.24 AIO01514.1 - 0.068 13.3 6.0 0.21 11.8 6.0 1.8 1 0 0 1 1 1 0 B-box zinc finger zf-MYND PF01753.18 AIO01514.1 - 0.096 12.8 12.4 0.22 11.6 12.4 1.6 1 0 0 1 1 1 0 MYND finger Kinesin PF00225.23 AIO01516.1 - 1.9e-80 270.3 0.0 4.6e-80 269.0 0.0 1.6 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 AIO01516.1 - 1e-22 80.7 0.0 2.2e-22 79.6 0.0 1.5 1 0 0 1 1 1 1 Microtubule binding Peptidase_S49_N PF08496.10 AIO01516.1 - 5.6 7.0 10.8 3.7 7.6 0.5 2.9 3 0 0 3 3 3 0 Peptidase family S49 N-terminal Dynein_heavy PF03028.15 AIO01517.1 - 5.8e-05 23.2 0.0 0.00012 22.1 0.0 1.5 1 0 0 1 1 1 1 Dynein heavy chain region D6 P-loop domain WD40 PF00400.32 AIO01517.1 - 1.1 10.2 20.7 11 7.1 0.0 7.2 9 0 0 9 9 9 0 WD domain, G-beta repeat Acid_PPase PF12689.7 AIO01518.1 - 6.7e-51 172.5 0.0 7.8e-51 172.3 0.0 1.0 1 0 0 1 1 1 1 Acid Phosphatase Hydrolase PF00702.26 AIO01518.1 - 0.042 14.1 0.0 0.096 13.0 0.0 1.5 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase TAF1_subA PF14929.6 AIO01518.1 - 0.074 12.5 0.0 0.086 12.3 0.0 1.1 1 0 0 1 1 1 0 TAF RNA Polymerase I subunit A NIF PF03031.18 AIO01518.1 - 0.092 12.5 0.0 0.25 11.1 0.0 1.7 1 1 0 1 1 1 0 NLI interacting factor-like phosphatase HAD PF12710.7 AIO01518.1 - 0.12 12.7 0.0 0.28 11.5 0.0 1.6 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase P53_C PF11619.8 AIO01519.1 - 0.084 12.9 0.0 0.27 11.3 0.0 1.9 1 0 0 1 1 1 0 Transcription factor P53 - C terminal domain DUF724 PF05266.14 AIO01519.1 - 0.11 12.3 0.4 0.36 10.6 0.4 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF724) Herpes_U30 PF04523.13 AIO01519.1 - 0.54 8.1 5.8 0.49 8.2 0.8 2.2 2 0 0 2 2 2 0 Herpes virus tegument protein U30 Tup_N PF08581.10 AIO01519.1 - 1.6 9.1 6.5 0.72 10.2 0.8 2.6 2 0 0 2 2 2 0 Tup N-terminal CLZ PF16526.5 AIO01519.1 - 2.7 8.4 8.5 12 6.3 0.9 3.2 2 0 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels DUF29 PF01724.16 AIO01522.1 - 0.052 13.8 0.0 0.084 13.1 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function DUF29 DUF2798 PF11391.8 AIO01523.1 - 1.3 9.1 5.5 11 6.1 3.5 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF2798) RTP801_C PF07809.11 AIO01524.1 - 0.01 15.7 0.0 1.1 9.2 0.0 2.2 2 0 0 2 2 2 0 RTP801 C-terminal region DUF1279 PF06916.13 AIO01524.1 - 0.013 16.0 0.1 0.032 14.8 0.1 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1279) CFAP91 PF14738.6 AIO01525.1 - 2e-45 154.6 3.2 2e-45 154.6 3.2 2.8 3 1 0 3 3 3 1 Cilia- and flagella-associated protein 91 DUF3761 PF12587.8 AIO01527.1 - 0.033 14.6 0.0 0.11 13.0 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3761) Baculo_IE-1 PF05290.11 AIO01528.1 - 0.0055 16.7 2.6 0.0089 16.0 2.6 1.2 1 0 0 1 1 1 1 Baculovirus immediate-early protein (IE-0) zf-C3HC4_3 PF13920.6 AIO01528.1 - 0.055 13.3 13.7 0.1 12.5 13.7 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Bac_small_YrzI PF09501.10 AIO01528.1 - 0.63 10.2 1.9 1.8 8.8 1.9 1.7 1 1 0 1 1 1 0 Probable sporulation protein (Bac_small_yrzI) Glyco_hydro_85 PF03644.13 AIO01529.1 - 2.6e-83 279.9 0.0 4.2e-83 279.2 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 85 Peptidase_C97 PF05903.14 AIO01529.1 - 1.8e-25 89.5 0.0 3.1e-25 88.8 0.0 1.4 1 0 0 1 1 1 1 PPPDE putative peptidase domain PUB PF09409.10 AIO01529.1 - 1.4e-14 53.7 0.0 1.1e-13 50.9 0.0 2.1 1 1 1 2 2 2 1 PUB domain DUF3421 PF11901.8 AIO01529.1 - 1.5e-07 31.4 0.8 0.0019 18.2 0.1 2.9 2 1 0 2 2 2 2 Protein of unknown function (DUF3421) Tmemb_cc2 PF10267.9 AIO01530.1 - 0.0064 15.7 2.8 0.0076 15.4 2.8 1.0 1 0 0 1 1 1 1 Predicted transmembrane and coiled-coil 2 protein CCDC106 PF15794.5 AIO01530.1 - 0.011 15.5 0.9 0.011 15.5 0.9 2.0 1 1 1 2 2 2 0 Coiled-coil domain-containing protein 106 Tup_N PF08581.10 AIO01530.1 - 0.016 15.5 1.6 0.024 14.9 1.6 1.3 1 0 0 1 1 1 0 Tup N-terminal PIN_2 PF10130.9 AIO01530.1 - 0.061 13.6 0.3 0.083 13.1 0.3 1.2 1 0 0 1 1 1 0 PIN domain HR1 PF02185.16 AIO01530.1 - 0.097 12.8 3.1 0.58 10.3 0.3 2.2 2 0 0 2 2 2 0 Hr1 repeat zf-MYND PF01753.18 AIO01532.1 - 3.4e-08 33.4 11.7 6.8e-08 32.5 11.7 1.5 1 0 0 1 1 1 1 MYND finger Pkinase PF00069.25 AIO01533.1 - 1.7e-54 185.0 0.0 6.7e-49 166.6 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 AIO01533.1 - 1.7e-39 135.6 0.0 1.6e-37 129.2 0.0 2.6 3 0 0 3 3 3 1 Protein tyrosine kinase Kdo PF06293.14 AIO01533.1 - 6.6e-05 22.4 0.0 0.00012 21.5 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 AIO01533.1 - 0.00012 21.5 0.0 0.00042 19.7 0.0 1.7 1 1 1 2 2 2 1 Kinase-like RIO1 PF01163.22 AIO01533.1 - 0.0083 15.7 0.0 0.022 14.3 0.0 1.5 1 1 0 1 1 1 1 RIO1 family APH PF01636.23 AIO01533.1 - 0.01 15.8 0.4 1.2 9.1 0.0 2.3 1 1 1 2 2 2 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 AIO01533.1 - 0.03 13.1 0.0 0.11 11.3 0.0 1.8 2 0 0 2 2 2 0 Fungal protein kinase Epimerase PF01370.21 AIO01534.1 - 2.5e-39 135.2 0.0 3.2e-39 134.8 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 AIO01534.1 - 1.4e-32 113.5 0.0 9.8e-31 107.4 0.0 2.6 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 AIO01534.1 - 1e-14 54.4 0.0 8.3e-14 51.4 0.0 2.1 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.19 AIO01534.1 - 9e-12 44.6 0.0 1e-09 37.8 0.0 2.2 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 AIO01534.1 - 1.5e-08 34.1 0.0 2.5e-08 33.4 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein KR PF08659.10 AIO01534.1 - 9.2e-06 25.7 0.0 2.9e-05 24.1 0.0 1.8 2 1 0 2 2 2 1 KR domain RmlD_sub_bind PF04321.17 AIO01534.1 - 4.5e-05 22.7 0.0 0.00023 20.4 0.0 2.1 2 1 0 2 2 2 1 RmlD substrate binding domain Sacchrp_dh_NADP PF03435.18 AIO01534.1 - 0.03 14.6 0.1 0.13 12.5 0.1 2.1 2 1 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain NAD_binding_10 PF13460.6 AIO01534.1 - 0.062 13.2 0.0 3 7.7 0.0 2.2 1 1 1 2 2 2 0 NAD(P)H-binding TrkA_N PF02254.18 AIO01534.1 - 0.077 13.3 0.1 3 8.2 0.0 2.8 3 0 0 3 3 3 0 TrkA-N domain DUF4232 PF14016.6 AIO01534.1 - 0.079 13.1 0.0 0.15 12.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4232) YAcAr PF10686.9 AIO01534.1 - 0.12 12.4 0.0 0.59 10.1 0.0 2.1 2 0 0 2 2 2 0 YspA, cpYpsA-related SLOG family CDC45 PF02724.14 AIO01536.1 - 7.7e-82 275.6 0.0 9.9e-82 275.2 0.0 1.1 1 0 0 1 1 1 1 CDC45-like protein FapA PF03961.13 AIO01537.1 - 2.8 6.4 6.0 0.8 8.2 2.4 1.9 2 0 0 2 2 2 0 Flagellar Assembly Protein A GIT_CC PF16559.5 AIO01537.1 - 5.5 6.9 8.6 12 5.9 0.5 3.6 3 0 0 3 3 3 0 GIT coiled-coil Rho guanine nucleotide exchange factor CoA_trans PF01144.23 AIO01538.1 - 1.5e-97 325.2 1.5 8.3e-61 205.1 0.4 2.0 2 0 0 2 2 2 2 Coenzyme A transferase AcetylCoA_hyd_C PF13336.6 AIO01538.1 - 0.016 15.2 0.0 0.029 14.3 0.0 1.4 1 0 0 1 1 1 0 Acetyl-CoA hydrolase/transferase C-terminal domain NCA2 PF08637.10 AIO01539.1 - 8.3e-37 126.9 0.1 1.7e-27 96.4 0.0 2.2 1 1 1 2 2 2 2 ATP synthase regulation protein NCA2 Tom22 PF04281.13 AIO01540.1 - 0.12 12.2 0.3 0.29 10.9 0.3 1.6 1 0 0 1 1 1 0 Mitochondrial import receptor subunit Tom22 BAR_3 PF16746.5 AIO01540.1 - 0.13 12.0 3.3 0.073 12.8 1.1 1.6 2 0 0 2 2 2 0 BAR domain of APPL family GRASP55_65 PF04495.14 AIO01541.1 - 9.5e-42 142.6 0.0 1.1e-36 126.2 0.0 2.2 1 1 1 2 2 2 2 GRASP55/65 PDZ-like domain HSP90 PF00183.18 AIO01542.1 - 7.6e-95 318.7 3.2 3.5e-93 313.3 0.6 2.0 1 1 1 2 2 2 2 Hsp90 protein HATPase_c_3 PF13589.6 AIO01542.1 - 5.3e-11 42.5 0.0 1.4e-10 41.2 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 AIO01542.1 - 3.4e-07 30.8 0.0 6.4e-07 29.9 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DPRP PF04244.13 AIO01542.1 - 0.0054 16.6 0.2 0.0095 15.8 0.2 1.3 1 0 0 1 1 1 1 Deoxyribodipyrimidine photo-lyase-related protein OSCP PF00213.18 AIO01542.1 - 0.072 13.2 0.2 0.16 12.1 0.2 1.5 1 0 0 1 1 1 0 ATP synthase delta (OSCP) subunit Ph1570 PF09638.10 AIO01542.1 - 0.093 12.6 0.0 1.5 8.6 0.0 2.3 2 0 0 2 2 2 0 Ph1570 protein MMR_HSR1 PF01926.23 AIO01543.1 - 4.5e-18 65.4 0.0 2.9e-13 49.9 0.0 2.4 2 0 0 2 2 2 2 50S ribosome-binding GTPase FeoB_N PF02421.18 AIO01543.1 - 7e-11 41.9 2.3 6.9e-09 35.4 0.2 2.8 3 0 0 3 3 3 2 Ferrous iron transport protein B GTP_EFTU PF00009.27 AIO01543.1 - 2e-05 24.2 0.0 0.00066 19.3 0.1 2.9 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 AIO01543.1 - 2.4e-05 24.3 0.7 0.00045 20.2 0.7 2.4 1 1 0 1 1 1 1 RsgA GTPase Dynamin_N PF00350.23 AIO01543.1 - 0.0016 18.5 0.7 0.035 14.1 0.2 2.8 2 1 1 3 3 3 1 Dynamin family AAA_18 PF13238.6 AIO01543.1 - 0.011 16.3 0.1 0.064 13.8 0.0 2.3 2 0 0 2 2 2 0 AAA domain MeaB PF03308.16 AIO01543.1 - 0.048 12.6 0.0 0.11 11.4 0.0 1.6 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Diphthamide_syn PF01866.17 AIO01544.1 - 7.2e-44 150.4 0.7 7e-24 84.8 0.0 3.0 2 1 0 2 2 2 2 Putative diphthamide synthesis protein TMEM119 PF15724.5 AIO01544.1 - 0.017 15.2 0.3 0.017 15.2 0.3 1.9 2 0 0 2 2 2 0 TMEM119 family PEN-2 PF10251.9 AIO01544.1 - 0.18 12.2 0.2 0.79 10.2 0.0 2.0 2 0 0 2 2 2 0 Presenilin enhancer-2 subunit of gamma secretase RE_NgoFVII PF09565.10 AIO01546.1 - 0.0044 16.4 3.8 0.011 15.1 3.8 1.6 1 0 0 1 1 1 1 NgoFVII restriction endonuclease DUF4448 PF14610.6 AIO01546.1 - 1.2 8.9 4.4 1.2 8.9 0.7 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF4448) zf-C3HC PF07967.13 AIO01547.1 - 0.039 14.0 0.2 16 5.6 0.0 2.8 3 0 0 3 3 3 0 C3HC zinc finger-like RILP PF11461.8 AIO01548.1 - 0.035 14.3 0.0 0.1 12.8 0.0 1.8 1 0 0 1 1 1 0 Rab interacting lysosomal protein Tox-WTIP PF15654.6 AIO01549.1 - 0.045 14.2 0.0 0.11 12.9 0.0 1.7 1 0 0 1 1 1 0 Toxin with a conserved tryptophan and TIP tripeptide motif KorB PF08535.10 AIO01550.1 - 0.054 13.5 0.0 0.13 12.3 0.0 1.6 1 0 0 1 1 1 0 KorB domain Rad51 PF08423.11 AIO01551.1 - 3.9e-34 118.1 0.0 1.4e-21 76.9 0.1 3.8 3 1 1 4 4 4 3 Rad51 AAA_25 PF13481.6 AIO01551.1 - 1.8e-08 34.2 0.0 4.3e-08 33.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain ATPase PF06745.13 AIO01551.1 - 2.3e-05 23.9 0.4 7.9e-05 22.1 0.2 1.9 2 0 0 2 2 2 1 KaiC RecA PF00154.21 AIO01551.1 - 0.0048 16.4 0.1 0.01 15.3 0.1 1.5 1 0 0 1 1 1 1 recA bacterial DNA recombination protein AAA_16 PF13191.6 AIO01551.1 - 0.075 13.4 0.1 0.67 10.3 0.0 2.5 3 0 0 3 3 3 0 AAA ATPase domain AAA PF00004.29 AIO01551.1 - 0.11 12.9 0.1 0.43 11.0 0.0 2.0 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Radial_spoke PF04712.12 AIO01552.1 - 9.4e-09 34.7 0.0 8.5e-07 28.3 0.0 2.1 2 0 0 2 2 2 2 Radial spokehead-like protein UDPGP PF01704.18 AIO01554.1 - 5.5e-28 97.7 0.0 8.5e-28 97.1 0.0 1.2 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase NTP_transf_3 PF12804.7 AIO01554.1 - 0.0025 18.2 0.4 0.0025 18.2 0.4 2.6 4 0 0 4 4 4 1 MobA-like NTP transferase domain NUC173 PF08161.12 AIO01555.1 - 5.4e-16 58.9 4.5 6.1e-15 55.4 2.1 3.4 2 1 0 2 2 2 1 NUC173 domain Peptidase_M32 PF02074.15 AIO01556.1 - 5.1e-155 517.0 0.0 5.7e-155 516.8 0.0 1.0 1 0 0 1 1 1 1 Carboxypeptidase Taq (M32) metallopeptidase Iso_dh PF00180.20 AIO01557.1 - 1.2e-105 353.6 0.0 1.5e-105 353.2 0.0 1.1 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase PdxA PF04166.12 AIO01557.1 - 0.0037 16.7 0.1 0.0067 15.9 0.1 1.3 1 0 0 1 1 1 1 Pyridoxal phosphate biosynthetic protein PdxA Kinesin PF00225.23 AIO01558.1 - 9.2e-102 340.4 0.3 1.6e-101 339.5 0.3 1.4 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 AIO01558.1 - 7.5e-21 74.6 0.0 2.7e-20 72.8 0.0 1.9 2 0 0 2 2 2 1 Microtubule binding AAA_22 PF13401.6 AIO01558.1 - 0.00012 22.4 3.4 0.032 14.5 0.0 3.8 4 0 0 4 4 4 1 AAA domain AAA_16 PF13191.6 AIO01558.1 - 0.00015 22.2 3.6 0.0069 16.8 0.0 4.3 4 0 0 4 4 4 1 AAA ATPase domain Ras PF00071.22 AIO01558.1 - 0.0046 16.6 0.0 0.51 9.9 0.0 2.9 3 0 0 3 3 2 1 Ras family Mito_fiss_reg PF05308.11 AIO01558.1 - 0.0062 16.7 0.2 0.019 15.0 0.2 1.8 1 0 0 1 1 1 1 Mitochondrial fission regulator RsgA_GTPase PF03193.16 AIO01558.1 - 0.0099 15.8 0.9 0.025 14.5 0.6 1.8 2 0 0 2 2 1 1 RsgA GTPase Mg_chelatase PF01078.21 AIO01558.1 - 0.016 14.6 0.0 0.36 10.2 0.0 2.6 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_28 PF13521.6 AIO01558.1 - 0.023 14.9 0.0 0.08 13.2 0.0 2.0 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 AIO01558.1 - 0.024 14.4 0.0 3.8 7.2 0.0 2.8 2 0 0 2 2 2 0 IstB-like ATP binding protein Roc PF08477.13 AIO01558.1 - 0.027 14.7 0.0 0.9 9.8 0.0 3.1 2 1 0 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase RNA_helicase PF00910.22 AIO01558.1 - 0.035 14.5 0.4 4.3 7.8 0.0 3.7 3 0 0 3 3 3 0 RNA helicase Kinesin_assoc PF16183.5 AIO01558.1 - 0.038 14.1 0.6 0.21 11.7 0.6 2.4 1 1 0 1 1 1 0 Kinesin-associated FtsK_SpoIIIE PF01580.18 AIO01558.1 - 0.041 13.2 3.9 2.5 7.4 0.2 3.3 4 0 0 4 4 4 0 FtsK/SpoIIIE family AAA_29 PF13555.6 AIO01558.1 - 0.043 13.6 0.0 0.3 10.9 0.0 2.2 2 0 0 2 2 2 0 P-loop containing region of AAA domain ABC_tran PF00005.27 AIO01558.1 - 0.047 14.2 0.1 0.23 12.0 0.0 2.2 2 0 0 2 2 2 0 ABC transporter MMR_HSR1 PF01926.23 AIO01558.1 - 0.056 13.5 0.8 5 7.3 0.3 2.8 2 0 0 2 2 2 0 50S ribosome-binding GTPase NACHT PF05729.12 AIO01558.1 - 0.076 12.9 0.3 0.93 9.4 0.0 2.6 2 0 0 2 2 2 0 NACHT domain AAA_24 PF13479.6 AIO01558.1 - 0.11 12.2 0.2 2.8 7.6 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 AIO01558.1 - 0.12 11.9 0.3 3.7 7.0 0.0 2.5 2 0 0 2 2 2 0 P-loop containing dynein motor region G-alpha PF00503.20 AIO01558.1 - 0.22 10.6 0.0 0.47 9.5 0.0 1.4 1 0 0 1 1 1 0 G-protein alpha subunit Peptidase_M17 PF00883.21 AIO01559.1 - 8.5e-90 301.2 0.1 1.2e-89 300.7 0.1 1.2 1 0 0 1 1 1 1 Cytosol aminopeptidase family, catalytic domain Pdase_M17_N2 PF18295.1 AIO01559.1 - 2.9e-30 105.0 1.8 5.6e-30 104.1 1.8 1.5 1 0 0 1 1 1 1 M17 aminopeptidase N-terminal domain 2 SAD_SRA PF02182.17 AIO01559.1 - 0.083 12.6 0.0 0.18 11.5 0.0 1.5 1 0 0 1 1 1 0 SAD/SRA domain 3HCDH_N PF02737.18 AIO01563.1 - 2.2e-41 141.7 0.0 4.2e-41 140.8 0.0 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ECH_1 PF00378.20 AIO01563.1 - 3.1e-30 105.3 0.0 5.2e-30 104.6 0.0 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase 3HCDH PF00725.22 AIO01563.1 - 1.5e-19 70.4 0.0 5.8e-09 36.4 0.0 3.5 3 0 0 3 3 3 2 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain ECH_2 PF16113.5 AIO01563.1 - 5.9e-13 49.0 0.0 9.7e-13 48.3 0.0 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase DAO PF01266.24 AIO01563.1 - 0.018 14.6 0.0 0.034 13.7 0.0 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 AIO01563.1 - 0.019 15.0 0.0 0.035 14.1 0.0 1.4 1 0 0 1 1 1 0 FAD-NAD(P)-binding Shikimate_DH PF01488.20 AIO01563.1 - 0.038 14.1 0.1 0.1 12.7 0.1 1.7 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Sacchrp_dh_NADP PF03435.18 AIO01563.1 - 0.061 13.6 0.0 0.12 12.7 0.0 1.5 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain NAD_Gly3P_dh_N PF01210.23 AIO01563.1 - 0.16 11.9 0.0 0.37 10.8 0.0 1.6 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Pyr_redox_2 PF07992.14 AIO01563.1 - 0.18 11.0 0.0 0.29 10.3 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Peptidase_M16_C PF05193.21 AIO01564.1 - 3.9e-19 69.4 0.0 7.2e-19 68.5 0.0 1.5 1 0 0 1 1 1 1 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 AIO01564.1 - 0.0011 19.0 0.0 0.0022 18.0 0.0 1.5 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) SRPRB PF09439.10 AIO01565.1 - 3.2e-21 75.6 0.0 6.2e-21 74.6 0.0 1.4 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.27 AIO01565.1 - 0.00018 21.1 0.1 0.00037 20.1 0.1 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 AIO01565.1 - 0.00089 19.3 0.0 0.0019 18.3 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase DUF463 PF04317.12 AIO01565.1 - 0.067 12.1 0.1 1.1 8.1 0.0 2.3 2 0 0 2 2 2 0 YcjX-like family, DUF463 WD40 PF00400.32 AIO01566.1 - 0.0004 21.1 1.2 20 6.2 0.0 5.1 5 0 0 5 5 5 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 AIO01566.1 - 0.0004 20.6 0.9 3.8 7.9 0.0 4.8 2 2 4 6 6 6 1 Anaphase-promoting complex subunit 4 WD40 domain Pep3_Vps18 PF05131.14 AIO01566.1 - 0.081 12.7 0.0 0.2 11.5 0.0 1.5 1 0 0 1 1 1 0 Pep3/Vps18/deep orange family LIM PF00412.22 AIO01567.1 - 1.3e-05 25.3 1.1 2.2e-05 24.6 1.1 1.4 1 0 0 1 1 1 1 LIM domain DUF2141 PF09912.9 AIO01567.1 - 0.1 12.5 0.0 0.33 10.9 0.0 1.9 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2141) DUF4193 PF13834.6 AIO01567.1 - 4.2 7.9 9.1 2.4 8.7 3.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4193) ThiF PF00899.21 AIO01568.1 - 2.8e-07 30.2 0.1 1.8e-05 24.2 0.0 2.3 2 0 0 2 2 2 2 ThiF family zf-CCHC PF00098.23 AIO01569.1 - 2.2 8.5 5.7 7.1 6.9 0.8 2.9 2 0 0 2 2 2 0 Zinc knuckle Bac_DnaA PF00308.18 AIO01570.1 - 0.15 11.9 4.0 0.39 10.5 4.0 1.7 1 0 0 1 1 1 0 Bacterial dnaA protein PKcGMP_CC PF16808.5 AIO01570.1 - 6.7 6.7 13.6 0.93 9.4 0.1 4.4 4 0 0 4 4 4 0 Coiled-coil N-terminus of cGMP-dependent protein kinase DnaJ PF00226.31 AIO01572.1 - 3.6e-09 36.6 0.2 1.2e-08 34.9 0.0 1.9 2 0 0 2 2 2 1 DnaJ domain Phage_holin_7_1 PF16081.5 AIO01572.1 - 5.8 7.1 6.4 1.1 9.4 1.6 2.0 2 0 0 2 2 2 0 Mycobacterial 2 TMS Phage Holin (M2 Hol) Family CDT1_C PF16679.5 AIO01572.1 - 6.3 7.3 9.6 2.3 8.7 4.0 3.0 3 1 0 3 3 3 0 DNA replication factor Cdt1 C-terminal domain MCM PF00493.23 AIO01573.1 - 3.2e-83 278.2 0.0 5.6e-83 277.5 0.0 1.3 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 AIO01573.1 - 3.1e-26 91.7 0.0 5.5e-26 90.9 0.0 1.3 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 AIO01573.1 - 1.9e-21 76.3 0.0 3.9e-21 75.3 0.0 1.6 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 AIO01573.1 - 3.8e-10 40.3 0.0 1.5e-09 38.4 0.0 2.1 2 0 0 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.21 AIO01573.1 - 1.5e-08 34.3 0.2 6.5e-07 28.9 0.0 2.6 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.26 AIO01573.1 - 0.00049 19.9 0.0 0.002 17.9 0.0 1.9 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_3 PF07726.11 AIO01573.1 - 0.0019 18.0 0.0 0.0042 17.0 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 AIO01573.1 - 0.08 12.9 0.0 0.35 10.9 0.0 2.1 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA PF00004.29 AIO01573.1 - 0.11 13.0 0.0 0.23 11.9 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Complex1_LYR PF05347.15 AIO01574.1 - 2.6e-05 24.2 1.2 4.3e-05 23.5 1.2 1.4 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Misat_Tub_SegII PF10644.9 AIO01574.1 - 0.055 13.8 0.0 0.07 13.4 0.0 1.2 1 0 0 1 1 1 0 Misato Segment II tubulin-like domain ketoacyl-synt PF00109.26 AIO01575.1 - 1.7e-39 135.9 2.8 2e-38 132.4 2.8 2.2 1 1 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 AIO01575.1 - 1.9e-27 95.6 0.4 4.3e-27 94.5 0.4 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain GTP_EFTU PF00009.27 AIO01577.1 - 2.3e-34 118.7 0.0 8e-34 116.9 0.0 1.9 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain IF-2 PF11987.8 AIO01577.1 - 1.2e-15 57.6 0.0 2.8e-15 56.3 0.0 1.7 1 0 0 1 1 1 1 Translation-initiation factor 2 GTP_EFTU_D2 PF03144.25 AIO01577.1 - 3.4e-10 40.2 1.1 2.2e-07 31.2 0.0 3.0 2 0 0 2 2 2 2 Elongation factor Tu domain 2 GTP_EFTU_D4 PF14578.6 AIO01577.1 - 1.9e-08 34.1 0.7 1.9e-08 34.1 0.7 1.9 2 0 0 2 2 2 1 Elongation factor Tu domain 4 MMR_HSR1 PF01926.23 AIO01577.1 - 4.8e-08 33.1 0.0 4.3e-07 30.0 0.0 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase Roc PF08477.13 AIO01577.1 - 6e-05 23.2 0.0 0.00014 22.1 0.0 1.6 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase ATP_bind_1 PF03029.17 AIO01577.1 - 0.005 16.7 0.0 0.018 14.9 0.0 1.9 1 1 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_16 PF13191.6 AIO01577.1 - 0.01 16.2 0.0 0.01 16.2 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain Ras PF00071.22 AIO01577.1 - 0.017 14.7 0.0 0.083 12.5 0.0 2.1 1 1 0 1 1 1 0 Ras family Cwf_Cwc_15 PF04889.12 AIO01577.1 - 2.1 8.0 33.6 5.1 6.8 33.6 1.5 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein CAF-1_p150 PF11600.8 AIO01577.1 - 4.7 6.9 49.1 5.1 6.8 27.5 2.5 2 0 0 2 2 2 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal DUF4520 PF15016.6 AIO01578.1 - 6.6e-22 77.4 0.1 1.3e-18 66.9 0.0 2.7 2 0 0 2 2 2 2 Domain of unknown function (DUF4520) POLO_box PF00659.18 AIO01578.1 - 0.0047 17.1 0.0 0.093 12.9 0.0 2.5 2 0 0 2 2 2 1 POLO box duplicated region UQ_con PF00179.26 AIO01580.1 - 4.1e-35 120.5 0.0 5.4e-35 120.1 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme BRE PF06113.12 AIO01580.1 - 0.15 10.9 0.0 0.2 10.5 0.0 1.1 1 0 0 1 1 1 0 Brain and reproductive organ-expressed protein (BRE) Beach PF02138.18 AIO01581.1 - 3.5e-97 325.1 0.0 6.9e-97 324.1 0.0 1.5 1 0 0 1 1 1 1 Beige/BEACH domain Laminin_G_3 PF13385.6 AIO01581.1 - 8.5e-08 32.5 0.5 1.9e-07 31.3 0.5 1.7 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily GTP_EFTU PF00009.27 AIO01582.1 - 9.3e-17 61.2 0.0 6.7e-16 58.4 0.0 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.25 AIO01582.1 - 3.2e-06 27.4 0.5 8.6e-06 26.1 0.5 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 GTP_EFTU_D3 PF03143.17 AIO01582.1 - 1.6e-05 25.2 0.2 4.5e-05 23.7 0.2 1.8 1 1 0 1 1 1 1 Elongation factor Tu C-terminal domain MMR_HSR1 PF01926.23 AIO01582.1 - 0.04 14.0 0.0 0.23 11.5 0.0 2.2 1 1 0 1 1 1 0 50S ribosome-binding GTPase Tape_meas_lam_C PF09718.10 AIO01583.1 - 0.022 14.9 0.1 0.045 13.9 0.1 1.5 1 1 0 1 1 1 0 Lambda phage tail tape-measure protein (Tape_meas_lam_C) TFIIS_C PF01096.18 AIO01584.1 - 1.4e-15 56.9 7.1 2.5e-15 56.0 7.1 1.5 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS) PWWP PF00855.17 AIO01584.1 - 1.8e-06 28.3 0.1 8.2e-06 26.1 0.0 2.1 2 0 0 2 2 2 1 PWWP domain Med26 PF08711.11 AIO01584.1 - 0.11 12.5 0.0 0.24 11.4 0.0 1.6 1 0 0 1 1 1 0 TFIIS helical bundle-like domain PWWP PF00855.17 AIO01585.1 - 6.5e-12 45.7 1.3 9.7e-12 45.1 0.0 1.9 2 0 0 2 2 2 1 PWWP domain Med26 PF08711.11 AIO01585.1 - 7e-08 32.4 0.0 1.6e-07 31.3 0.0 1.6 1 0 0 1 1 1 1 TFIIS helical bundle-like domain Zn_ribbon_SprT PF17283.2 AIO01585.1 - 0.00021 21.1 0.9 0.00071 19.4 0.9 1.9 1 0 0 1 1 1 1 SprT-like zinc ribbon domain Lar_restr_allev PF14354.6 AIO01585.1 - 0.0027 18.1 0.4 0.0074 16.6 0.4 1.8 1 0 0 1 1 1 1 Restriction alleviation protein Lar Zn_Tnp_IS1595 PF12760.7 AIO01585.1 - 0.038 14.0 0.9 0.038 14.0 0.9 2.1 2 0 0 2 2 2 0 Transposase zinc-ribbon domain CDC27 PF09507.10 AIO01585.1 - 0.21 10.9 11.8 0.31 10.4 11.8 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 zinc_ribbon_4 PF13717.6 AIO01585.1 - 0.28 11.2 1.2 4 7.4 0.1 2.5 2 0 0 2 2 2 0 zinc-ribbon domain SRP-alpha_N PF04086.13 AIO01585.1 - 3 7.7 13.8 4.6 7.1 13.8 1.2 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Zn_Tnp_IS1 PF03811.13 AIO01585.1 - 8.4 6.2 8.7 1.2 9.0 0.9 2.7 2 0 0 2 2 2 0 InsA N-terminal domain CHAP PF05257.16 AIO01586.1 - 2.1e-17 63.5 0.0 4e-17 62.6 0.0 1.5 1 0 0 1 1 1 1 CHAP domain Amidase_6 PF12671.7 AIO01586.1 - 0.019 15.1 0.0 0.043 13.9 0.0 1.5 1 1 0 1 1 1 0 Putative amidase domain ABC2_membrane_3 PF12698.7 AIO01587.1 - 0.066 12.3 0.5 0.13 11.4 0.5 1.5 1 0 0 1 1 1 0 ABC-2 family transporter protein Macoilin PF09726.9 AIO01587.1 - 0.95 7.9 8.1 1.3 7.4 8.1 1.2 1 0 0 1 1 1 0 Macoilin family CHAP PF05257.16 AIO01588.1 - 2.5e-15 56.8 0.0 4.7e-15 55.9 0.0 1.5 1 0 0 1 1 1 1 CHAP domain CHAP PF05257.16 AIO01589.1 - 0.00012 22.6 0.1 0.00057 20.4 0.1 2.2 1 1 0 1 1 1 1 CHAP domain bHLH-MYC_N PF14215.6 AIO01591.1 - 0.048 13.9 0.2 0.16 12.2 0.0 1.9 2 0 0 2 2 2 0 bHLH-MYC and R2R3-MYB transcription factors N-terminal LapA_dom PF06305.11 AIO01592.1 - 0.13 12.1 0.2 0.29 11.0 0.2 1.5 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain DUF5476 PF17570.2 AIO01592.1 - 0.66 10.4 15.8 1.8e+04 -5.7 15.8 3.9 1 1 0 1 1 1 0 Family of unknown function (DUF5476) Kinesin PF00225.23 AIO01593.1 - 0.016 14.2 0.0 1.2 8.0 0.0 3.0 2 2 0 2 2 2 0 Kinesin motor domain RRM_occluded PF16842.5 AIO01594.1 - 0.1 12.5 0.2 0.96 9.3 0.0 2.7 3 0 0 3 3 3 0 Occluded RNA-recognition motif DUF4835 PF16119.5 AIO01598.1 - 0.077 12.1 0.4 0.14 11.2 0.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4835) DOR PF14839.6 AIO01601.1 - 5.6 6.8 10.1 3.5 7.5 3.0 2.1 2 0 0 2 2 2 0 DOR family SurA_N_3 PF13624.6 AIO01602.1 - 0.0095 15.7 1.7 0.027 14.3 1.7 1.7 1 0 0 1 1 1 1 SurA N-terminal domain DUF658 PF04936.12 AIO01602.1 - 1.1 8.9 2.6 1.9 8.2 2.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF658) DUF3454 PF11936.8 AIO01602.1 - 8.6 6.9 17.6 0.52 10.8 11.8 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3454) RAP1 PF07218.11 AIO01604.1 - 0.98 7.6 7.5 1.8 6.8 7.5 1.3 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) ABC_tran PF00005.27 AIO01606.1 - 4e-11 43.6 0.0 5.1e-05 23.8 0.0 2.8 2 0 0 2 2 2 2 ABC transporter SbcCD_C PF13558.6 AIO01606.1 - 0.001 19.2 0.2 0.011 15.9 0.0 2.6 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_22 PF13401.6 AIO01606.1 - 0.11 12.8 0.0 0.49 10.7 0.0 2.2 2 0 0 2 2 2 0 AAA domain Tyr-DNA_phospho PF06087.12 AIO01607.1 - 3.7e-68 230.4 0.0 5.4e-68 229.8 0.0 1.2 1 0 0 1 1 1 1 Tyrosyl-DNA phosphodiesterase OGFr_III PF04680.13 AIO01608.1 - 6e-05 23.4 2.7 0.00016 22.1 2.7 1.8 1 0 0 1 1 1 1 Opioid growth factor receptor repeat SH2_2 PF14633.6 AIO01610.1 - 2e-21 76.4 0.1 3.7e-21 75.5 0.1 1.3 1 0 0 1 1 1 1 SH2 domain YqgF PF14639.6 AIO01610.1 - 5.5e-11 42.5 0.0 5.7e-10 39.2 0.0 2.2 2 0 0 2 2 2 1 Holliday-junction resolvase-like of SPT6 Tex_YqgF PF16921.5 AIO01610.1 - 0.0012 19.3 0.0 0.0027 18.1 0.0 1.6 1 0 0 1 1 1 1 Tex protein YqgF-like domain HTH_5 PF01022.20 AIO01610.1 - 0.29 11.1 1.2 0.43 10.5 0.1 1.9 2 0 0 2 2 2 0 Bacterial regulatory protein, arsR family Trypsin_2 PF13365.6 AIO01613.1 - 7.3e-06 27.0 0.1 2.2e-05 25.4 0.1 1.8 1 1 0 1 1 1 1 Trypsin-like peptidase domain IL17 PF06083.11 AIO01613.1 - 0.055 13.9 0.0 0.11 13.0 0.0 1.5 1 0 0 1 1 1 0 Interleukin-17 Trypsin PF00089.26 AIO01613.1 - 0.078 12.8 0.4 0.16 11.7 0.2 1.6 2 0 0 2 2 2 0 Trypsin Ribosomal_S13_N PF08069.12 AIO01614.1 - 8.4e-25 86.6 1.8 1.6e-24 85.7 1.8 1.5 1 0 0 1 1 1 1 Ribosomal S13/S15 N-terminal domain Ribosomal_S15 PF00312.22 AIO01614.1 - 1.9e-13 50.4 1.1 3.2e-13 49.7 1.1 1.3 1 0 0 1 1 1 1 Ribosomal protein S15 Acyl-CoA_ox_N PF14749.6 AIO01615.1 - 0.087 13.4 1.3 0.38 11.3 0.2 2.5 2 0 0 2 2 2 0 Acyl-coenzyme A oxidase N-terminal DUF1664 PF07889.12 AIO01616.1 - 0.034 14.2 1.4 3.5 7.7 0.1 3.7 3 1 1 4 4 4 0 Protein of unknown function (DUF1664) NPV_P10 PF05531.12 AIO01616.1 - 0.04 14.4 0.6 40 4.8 0.0 3.7 4 0 0 4 4 4 0 Nucleopolyhedrovirus P10 protein FAM76 PF16046.5 AIO01616.1 - 0.054 12.9 0.2 0.11 11.9 0.2 1.5 1 0 0 1 1 1 0 FAM76 protein Med9 PF07544.13 AIO01616.1 - 0.069 13.3 2.7 2.5 8.3 0.2 3.3 3 0 0 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 Apolipoprotein PF01442.18 AIO01616.1 - 0.26 11.2 15.3 0.83 9.5 3.4 2.9 2 1 0 2 2 2 0 Apolipoprotein A1/A4/E domain DUF4407 PF14362.6 AIO01616.1 - 0.31 10.4 5.0 0.87 8.9 0.7 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) HisKA_3 PF07730.13 AIO01616.1 - 1.6 9.3 7.7 35 5.0 0.0 4.5 3 1 0 3 3 3 0 Histidine kinase FliT PF05400.13 AIO01616.1 - 8.6 7.3 14.1 7.1 7.5 0.6 4.1 3 2 0 3 3 3 0 Flagellar protein FliT Baculo_PEP_C PF04513.12 AIO01616.1 - 9.7 6.2 10.4 90 3.1 0.1 4.3 3 2 0 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF4381 PF14316.6 AIO01617.1 - 0.011 15.9 0.0 0.028 14.7 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) CoA_binding_3 PF13727.6 AIO01617.1 - 0.081 12.9 0.1 0.39 10.7 0.0 2.0 2 0 0 2 2 2 0 CoA-binding domain EphA2_TM PF14575.6 AIO01617.1 - 0.39 11.6 0.0 0.39 11.6 0.0 4.0 3 2 0 3 3 3 0 Ephrin type-A receptor 2 transmembrane domain LSM PF01423.22 AIO01618.1 - 1.3e-14 53.6 0.1 1.9e-14 53.1 0.1 1.2 1 0 0 1 1 1 1 LSM domain Zip PF02535.22 AIO01619.1 - 1.1e-35 123.5 16.6 4e-34 118.3 16.6 2.0 1 1 0 1 1 1 1 ZIP Zinc transporter Coatomer_WDAD PF04053.14 AIO01620.1 - 2.4e-138 461.9 0.0 4.1e-138 461.2 0.0 1.4 1 0 0 1 1 1 1 Coatomer WD associated region WD40 PF00400.32 AIO01620.1 - 2.2e-27 94.8 1.5 4.1e-07 30.6 0.0 6.1 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 AIO01620.1 - 5e-08 33.1 0.0 2.5 8.5 0.0 6.5 4 3 3 7 7 7 3 Anaphase-promoting complex subunit 4 WD40 domain TPR_8 PF13181.6 AIO01620.1 - 0.017 15.3 0.3 0.19 12.0 0.0 2.8 1 1 3 4 4 4 0 Tetratricopeptide repeat Clathrin PF00637.20 AIO01620.1 - 0.072 13.0 1.0 1.8 8.5 0.0 2.6 1 1 1 2 2 2 0 Region in Clathrin and VPS zf-RanBP PF00641.18 AIO01621.1 - 1.1e-14 53.4 42.3 1.4e-06 27.5 6.4 5.5 5 0 0 5 5 5 5 Zn-finger in Ran binding protein and others Haem_bd PF14376.6 AIO01621.1 - 0.029 14.3 4.9 0.063 13.2 0.0 3.0 3 0 0 3 3 3 0 Haem-binding domain Cytochrom_c3_2 PF14537.6 AIO01621.1 - 0.064 13.7 19.2 1.3 9.5 3.3 3.6 2 2 0 2 2 2 0 Cytochrome c3 RecR PF02132.15 AIO01621.1 - 0.067 12.8 0.8 0.067 12.8 0.8 4.5 5 0 0 5 5 5 0 RecR protein Paired_CXXCH_1 PF09699.10 AIO01621.1 - 0.29 10.9 15.8 1.3 8.9 1.8 4.1 3 0 0 3 3 3 0 Doubled CXXCH motif (Paired_CXXCH_1) DZR PF12773.7 AIO01621.1 - 0.44 10.6 30.7 2.5 8.2 0.3 4.4 3 1 0 3 3 3 0 Double zinc ribbon DUF3615 PF12274.8 AIO01621.1 - 0.74 10.4 0.0 0.74 10.4 0.0 4.0 4 0 0 4 4 4 0 Protein of unknown function (DUF3615) zinc_ribbon_2 PF13240.6 AIO01621.1 - 3.1 7.6 18.7 0.41 10.4 0.3 4.4 4 0 0 4 4 4 0 zinc-ribbon domain Cytochrom_C PF00034.21 AIO01621.1 - 5.9 8.1 7.2 1e+02 4.1 0.1 3.4 3 0 0 3 3 3 0 Cytochrome c EF-hand_7 PF13499.6 AIO01623.1 - 4.2e-06 27.1 0.0 9.3e-05 22.8 0.0 2.9 2 1 1 3 3 3 1 EF-hand domain pair EF-hand_6 PF13405.6 AIO01623.1 - 0.00023 20.8 0.0 0.014 15.3 0.0 3.0 2 0 0 2 2 2 1 EF-hand domain EF-hand_5 PF13202.6 AIO01623.1 - 0.0011 18.3 0.0 0.003 17.0 0.0 1.7 1 0 0 1 1 1 1 EF hand EF-hand_1 PF00036.32 AIO01623.1 - 0.0019 17.6 0.0 0.039 13.5 0.0 2.9 3 0 0 3 3 3 1 EF hand Bac_A_amyl_C PF18612.1 AIO01623.1 - 0.17 11.7 0.0 0.31 10.8 0.0 1.4 1 0 0 1 1 1 0 Bacterial Alpha amylase C-terminal domain Ribosomal_L44 PF00935.19 AIO01624.1 - 1.2e-31 109.0 9.1 1.7e-31 108.5 9.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L44 CCT_2 PF09425.10 AIO01626.1 - 0.072 13.0 4.2 0.17 11.8 1.9 2.4 2 0 0 2 2 2 0 Divergent CCT motif ABC_tran PF00005.27 AIO01627.1 - 3.1e-17 63.4 0.0 5.2e-17 62.6 0.0 1.4 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 AIO01627.1 - 0.00076 19.0 0.0 0.015 14.8 0.0 1.9 1 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain Cys_Met_Meta_PP PF01053.20 AIO01627.1 - 0.012 14.2 0.0 0.025 13.1 0.0 1.4 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme AAA_29 PF13555.6 AIO01627.1 - 0.015 15.0 0.0 0.033 13.9 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.6 AIO01627.1 - 0.039 14.3 0.3 0.13 12.6 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain MMR_HSR1 PF01926.23 AIO01627.1 - 0.23 11.6 0.1 0.55 10.3 0.1 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase FA_desaturase PF00487.24 AIO01628.1 - 3.9e-24 85.9 32.0 3.9e-24 85.9 32.0 1.6 1 1 1 2 2 2 2 Fatty acid desaturase PK PF00224.21 AIO01629.1 - 5.2e-153 509.0 1.3 6.6e-153 508.7 1.3 1.1 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.16 AIO01629.1 - 7.9e-28 97.0 1.6 1.7e-27 96.0 0.2 2.3 3 0 0 3 3 3 1 Pyruvate kinase, alpha/beta domain HpcH_HpaI PF03328.14 AIO01629.1 - 5.4e-05 22.4 0.6 0.00017 20.8 0.5 1.8 1 1 1 2 2 2 1 HpcH/HpaI aldolase/citrate lyase family Peripla_BP_1 PF00532.21 AIO01629.1 - 0.048 13.1 0.0 0.17 11.2 0.0 2.0 2 0 0 2 2 2 0 Periplasmic binding proteins and sugar binding domain of LacI family IMPDH PF00478.25 AIO01629.1 - 0.47 9.4 5.4 0.39 9.7 0.1 2.6 3 0 0 3 3 3 0 IMP dehydrogenase / GMP reductase domain PI-PLC-X PF00388.19 AIO01630.1 - 1.2e-59 200.1 0.0 2e-59 199.3 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.19 AIO01630.1 - 5.2e-33 113.8 0.1 2e-32 111.9 0.0 2.0 2 0 0 2 2 2 1 Phosphatidylinositol-specific phospholipase C, Y domain EF-hand_1 PF00036.32 AIO01630.1 - 2.1e-05 23.7 3.0 3.8e-05 22.9 2.0 2.0 2 0 0 2 2 2 1 EF hand EF-hand_7 PF13499.6 AIO01630.1 - 0.00017 22.0 0.2 0.00047 20.6 0.2 1.8 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_8 PF13833.6 AIO01630.1 - 0.00017 21.3 0.7 0.0004 20.2 0.7 1.6 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_10 PF14788.6 AIO01630.1 - 0.0042 16.9 1.9 0.0091 15.8 1.9 1.6 1 0 0 1 1 1 1 EF hand EF-hand_4 PF12763.7 AIO01630.1 - 0.0049 16.8 0.0 0.013 15.4 0.0 1.7 1 0 0 1 1 1 1 Cytoskeletal-regulatory complex EF hand EF-hand_6 PF13405.6 AIO01630.1 - 0.0071 16.2 1.8 0.0071 16.2 1.8 2.2 2 0 0 2 2 2 1 EF-hand domain C2 PF00168.30 AIO01630.1 - 0.026 14.8 0.0 0.058 13.7 0.0 1.6 1 0 0 1 1 1 0 C2 domain Transket_pyr PF02779.24 AIO01631.1 - 4.4e-39 134.0 0.0 8.5e-39 133.1 0.0 1.5 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 AIO01631.1 - 2.8e-35 120.9 0.0 6.5e-35 119.7 0.0 1.6 1 0 0 1 1 1 1 Transketolase, C-terminal domain PFOR_II PF17147.4 AIO01631.1 - 1.1e-05 25.6 0.0 2e-05 24.8 0.0 1.4 1 0 0 1 1 1 1 Pyruvate:ferredoxin oxidoreductase core domain II Band_7 PF01145.25 AIO01633.1 - 2.1e-24 86.5 4.6 3.5e-24 85.8 4.6 1.4 1 1 0 1 1 1 1 SPFH domain / Band 7 family TrkH PF02386.16 AIO01634.1 - 9.9e-09 34.2 2.7 9.9e-09 34.2 2.7 3.4 3 1 0 3 3 3 3 Cation transport protein UCR_14kD PF02271.16 AIO01636.1 - 7.7e-08 32.2 0.1 4.5e-07 29.8 0.0 1.9 2 0 0 2 2 2 1 Ubiquinol-cytochrome C reductase complex 14kD subunit Clat_adaptor_s PF01217.20 AIO01637.1 - 1.1e-10 41.6 0.0 1.6e-10 41.1 0.0 1.1 1 0 0 1 1 1 1 Clathrin adaptor complex small chain OSR1_C PF12202.8 AIO01637.1 - 0.13 12.5 0.0 0.32 11.3 0.0 1.7 1 0 0 1 1 1 0 Oxidative-stress-responsive kinase 1 C-terminal domain LMBR1 PF04791.16 AIO01638.1 - 2.9e-18 66.1 26.4 1.4e-13 50.7 6.7 2.1 1 1 1 2 2 2 2 LMBR1-like membrane protein Arf PF00025.21 AIO01639.1 - 1.1e-64 217.2 0.1 1.2e-64 217.0 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.20 AIO01639.1 - 1.8e-13 50.4 1.7 2.3e-08 33.6 0.1 2.4 1 1 1 2 2 2 2 G-protein alpha subunit Roc PF08477.13 AIO01639.1 - 1e-11 45.1 0.0 1.4e-11 44.6 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Gtr1_RagA PF04670.12 AIO01639.1 - 3.2e-10 39.8 0.0 3.8e-10 39.5 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 AIO01639.1 - 2.3e-07 30.4 0.0 3e-07 30.0 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 AIO01639.1 - 6.1e-07 29.5 0.0 8.6e-07 29.0 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Ras PF00071.22 AIO01639.1 - 7.9e-07 28.8 0.0 9.6e-07 28.5 0.0 1.1 1 0 0 1 1 1 1 Ras family GTP_EFTU PF00009.27 AIO01639.1 - 0.00022 20.9 0.0 0.0016 18.0 0.0 1.9 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.18 AIO01639.1 - 0.00095 18.7 0.1 0.0034 16.9 0.1 1.9 1 1 0 1 1 1 1 Ferrous iron transport protein B cobW PF02492.19 AIO01639.1 - 0.013 15.1 0.1 0.16 11.5 0.0 2.0 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain TniB PF05621.11 AIO01639.1 - 0.18 11.2 0.2 0.52 9.7 0.0 1.7 2 0 0 2 2 2 0 Bacterial TniB protein Mito_carr PF00153.27 AIO01641.1 - 3.1e-06 27.0 2.6 0.057 13.3 0.0 2.6 2 1 0 2 2 2 2 Mitochondrial carrier protein SHE3 PF17078.5 AIO01644.1 - 0.00087 19.1 12.2 0.00087 19.1 12.2 6.9 1 1 4 6 6 6 2 SWI5-dependent HO expression protein 3 JIP_LZII PF16471.5 AIO01644.1 - 0.0072 16.5 7.3 0.0072 16.5 7.3 10.2 6 4 7 13 13 13 1 JNK-interacting protein leucine zipper II ADIP PF11559.8 AIO01644.1 - 0.011 15.9 8.2 0.011 15.9 8.2 10.2 2 2 10 12 12 12 0 Afadin- and alpha -actinin-Binding DUF3287 PF11690.8 AIO01644.1 - 0.047 13.4 1.7 0.37 10.5 1.7 2.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3287) FlaC_arch PF05377.11 AIO01644.1 - 1.2 9.6 43.1 6.4 7.3 0.2 10.3 8 3 4 12 12 12 0 Flagella accessory protein C (FlaC) WD40_alt PF14077.6 AIO01644.1 - 6.3 6.8 11.1 53 3.8 0.2 5.0 4 0 0 4 4 4 0 Alternative WD40 repeat motif NIF PF03031.18 AIO01645.1 - 3.2e-32 111.5 0.0 4.5e-32 111.0 0.0 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Hydrolase PF00702.26 AIO01645.1 - 0.0002 21.7 0.0 0.00028 21.2 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 AIO01645.1 - 0.0012 19.3 0.0 0.0053 17.2 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase DUF705 PF05152.12 AIO01645.1 - 0.1 12.1 0.0 0.16 11.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF705) FlgM PF04316.13 AIO01646.1 - 0.89 10.0 11.0 0.35 11.2 2.2 5.2 2 0 0 2 2 2 0 Anti-sigma-28 factor, FlgM DUF1242 PF06842.12 AIO01647.1 - 4.2e-10 39.3 0.8 5.7e-10 38.8 0.8 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1242) DnaJ PF00226.31 AIO01649.1 - 7.1e-05 22.9 0.0 0.00029 20.9 0.0 2.1 2 1 0 2 2 2 1 DnaJ domain zf_CCCH_4 PF18345.1 AIO01649.1 - 0.046 13.8 1.6 0.046 13.8 1.6 2.3 2 0 0 2 2 2 0 Zinc finger domain zf-CCCH PF00642.24 AIO01649.1 - 1.2 9.2 8.9 0.054 13.4 3.0 1.9 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Torus PF16131.5 AIO01649.1 - 1.7 9.4 5.8 0.5 11.1 1.3 2.3 3 0 0 3 3 3 0 Torus domain Ribosomal_L7Ae PF01248.26 AIO01650.1 - 1e-24 86.1 0.0 1.1e-24 85.9 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family IF3_N PF05198.16 AIO01650.1 - 0.024 14.9 0.0 0.038 14.2 0.0 1.2 1 0 0 1 1 1 0 Translation initiation factor IF-3, N-terminal domain Hydrolase_6 PF13344.6 AIO01650.1 - 0.095 12.8 0.0 0.12 12.5 0.0 1.2 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase ArfGap PF01412.18 AIO01652.1 - 4.1e-29 101.0 0.1 8.1e-29 100.1 0.1 1.4 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf PHO4 PF01384.20 AIO01653.1 - 0.07 12.2 0.1 0.07 12.2 0.1 1.0 1 0 0 1 1 1 0 Phosphate transporter family DUF3270 PF11674.8 AIO01653.1 - 0.19 12.0 1.0 0.36 11.0 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3270) 3HCDH PF00725.22 AIO01656.1 - 3.3e-11 43.6 0.1 0.00013 22.5 0.0 2.6 2 0 0 2 2 2 2 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain Nup96 PF12110.8 AIO01657.1 - 0.035 13.2 0.1 0.098 11.8 0.1 1.7 2 0 0 2 2 2 0 Nuclear protein 96 RRF PF01765.19 AIO01657.1 - 0.072 13.0 0.0 0.14 12.1 0.0 1.4 1 0 0 1 1 1 0 Ribosome recycling factor Drc1-Sld2 PF11719.8 AIO01657.1 - 0.093 12.3 3.5 0.097 12.2 0.3 2.2 2 1 1 3 3 3 0 DNA replication and checkpoint protein Ank_2 PF12796.7 AIO01658.1 - 1.3e-09 38.5 0.0 3.8e-08 33.8 0.0 2.5 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 AIO01658.1 - 6.8e-09 36.1 0.0 7.9e-05 23.1 0.0 3.0 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 AIO01658.1 - 9.1e-08 31.8 0.1 0.0052 17.2 0.0 3.5 3 0 0 3 3 3 2 Ankyrin repeat Ank PF00023.30 AIO01658.1 - 0.00027 21.2 0.1 0.035 14.6 0.0 3.3 3 0 0 3 3 3 1 Ankyrin repeat Ank_5 PF13857.6 AIO01658.1 - 0.00047 20.4 0.0 0.011 16.1 0.0 2.5 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Aminotran_1_2 PF00155.21 AIO01659.1 - 2e-48 165.4 0.0 2.4e-48 165.2 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 AIO01659.1 - 0.0019 17.6 0.0 0.018 14.4 0.0 2.0 1 1 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Beta_elim_lyase PF01212.21 AIO01659.1 - 0.063 12.5 0.0 0.14 11.4 0.0 1.4 1 1 0 1 1 1 0 Beta-eliminating lyase adh_short PF00106.25 AIO01660.1 - 2.1e-41 141.5 0.2 2.9e-41 141.1 0.2 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 AIO01660.1 - 1.8e-25 89.9 0.4 2.5e-25 89.4 0.4 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 AIO01660.1 - 1.8e-15 57.3 0.6 2.8e-15 56.7 0.6 1.3 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 AIO01660.1 - 0.01 15.0 0.0 0.013 14.7 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Eno-Rase_NADH_b PF12242.8 AIO01660.1 - 0.07 12.9 0.1 0.19 11.5 0.1 1.8 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase TGBp3 PF02495.17 AIO01660.1 - 0.13 11.9 0.2 0.27 10.9 0.2 1.5 1 0 0 1 1 1 0 Triple gene block 3 ECH_1 PF00378.20 AIO01663.1 - 1.1e-49 169.1 0.1 1.7e-49 168.4 0.1 1.4 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 AIO01663.1 - 4.1e-25 89.0 0.3 1.4e-22 80.7 0.1 2.1 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase DEAD PF00270.29 AIO01664.1 - 5.4e-45 153.3 0.4 7.7e-45 152.8 0.4 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 AIO01664.1 - 1.6e-28 99.2 1.4 7.2e-28 97.2 0.9 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ERCC3_RAD25_C PF16203.5 AIO01664.1 - 0.00068 18.9 0.1 0.001 18.4 0.1 1.2 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase AAA_19 PF13245.6 AIO01664.1 - 0.0057 17.0 0.3 0.01 16.2 0.3 1.4 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 AIO01664.1 - 0.006 16.9 0.3 0.018 15.3 0.3 1.8 1 1 0 1 1 1 1 AAA domain AAA PF00004.29 AIO01664.1 - 0.12 12.9 0.8 1.9 8.9 0.8 2.6 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Thioredoxin_8 PF13905.6 AIO01665.1 - 4.7e-05 23.6 0.1 0.015 15.6 0.0 2.5 1 1 1 2 2 2 2 Thioredoxin-like Thioredoxin PF00085.20 AIO01665.1 - 9.4e-05 22.4 0.0 0.00021 21.2 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 AIO01665.1 - 0.032 14.7 0.1 0.15 12.5 0.1 2.0 1 1 0 1 1 1 0 Thioredoxin-like domain Thioredoxin_7 PF13899.6 AIO01665.1 - 0.068 13.4 0.0 0.94 9.7 0.0 2.5 2 0 0 2 2 2 0 Thioredoxin-like Ribosomal_S3Ae PF01015.18 AIO01667.1 - 5.1e-68 228.6 4.3 6e-68 228.4 4.3 1.0 1 0 0 1 1 1 1 Ribosomal S3Ae family DNA_pol3_delt_C PF14840.6 AIO01667.1 - 0.12 12.7 2.7 0.21 11.9 2.3 1.5 1 1 0 1 1 1 0 Processivity clamp loader gamma complex DNA pol III C-term SHIPPO-rpt PF07004.12 AIO01668.1 - 1.7e-13 50.8 16.8 0.1 13.6 0.1 9.5 9 0 0 9 9 9 6 Sperm-tail PG-rich repeat Arrestin_N PF00339.29 AIO01669.1 - 1.2e-07 31.8 0.0 3.1e-07 30.6 0.0 1.6 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain HAP2-GCS1 PF10699.9 AIO01670.1 - 4.3e-20 71.4 0.1 9.2e-20 70.4 0.1 1.6 1 0 0 1 1 1 1 Male gamete fusion factor DC_STAMP PF07782.13 AIO01670.1 - 0.26 11.1 3.5 0.14 12.0 0.5 1.9 2 0 0 2 2 2 0 DC-STAMP-like protein DUF4131 PF13567.6 AIO01670.1 - 1 9.0 4.7 13 5.4 0.6 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) Pkinase PF00069.25 AIO01671.1 - 1.6e-50 171.9 0.1 1.4e-31 109.8 0.0 3.3 3 0 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.17 AIO01671.1 - 1.1e-23 83.9 0.4 3.4e-17 62.6 0.1 3.2 3 0 0 3 3 3 2 Protein tyrosine kinase EF-hand_7 PF13499.6 AIO01671.1 - 7.1e-09 36.0 0.8 0.00047 20.5 0.1 2.7 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 AIO01671.1 - 1.1e-07 31.3 0.0 0.0071 16.2 0.0 3.0 2 0 0 2 2 2 2 EF-hand domain Kinase-like PF14531.6 AIO01671.1 - 6.8e-05 22.3 0.0 0.071 12.4 0.0 2.2 2 0 0 2 2 2 2 Kinase-like EF-hand_1 PF00036.32 AIO01671.1 - 9.2e-05 21.7 0.0 0.15 11.7 0.0 3.3 3 0 0 3 3 3 2 EF hand Kdo PF06293.14 AIO01671.1 - 0.04 13.3 0.0 0.076 12.4 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family LRR_8 PF13855.6 AIO01672.1 - 1e-22 79.6 14.6 6.1e-05 22.7 0.4 6.1 5 1 1 6 6 6 5 Leucine rich repeat LRR_4 PF12799.7 AIO01672.1 - 1.3e-16 60.4 10.6 0.00035 20.9 0.5 6.3 6 1 0 6 6 6 5 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 AIO01672.1 - 1.6e-06 27.9 2.4 13 6.8 0.0 6.9 6 0 0 6 6 6 3 Leucine Rich Repeat LRR_4 PF12799.7 AIO01673.1 - 1.1e-20 73.4 13.2 0.0033 17.8 0.0 7.3 6 1 1 7 7 7 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 AIO01673.1 - 3.1e-14 52.5 23.7 2e-06 27.4 1.3 5.3 3 2 3 6 6 6 5 Leucine rich repeat FNIP PF05725.12 AIO01673.1 - 0.00043 20.4 2.0 0.83 9.9 0.0 4.5 5 1 0 5 5 5 2 FNIP Repeat LRR_1 PF00560.33 AIO01673.1 - 0.0044 17.4 15.9 28 5.8 0.0 8.9 9 2 0 9 9 9 1 Leucine Rich Repeat LRR_6 PF13516.6 AIO01673.1 - 0.23 11.6 7.5 4.7 7.5 0.1 4.7 4 0 0 4 4 4 0 Leucine Rich repeat DUF3079 PF11278.8 AIO01673.1 - 1.4 8.8 4.8 1.6 8.6 0.4 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3079) LRR_8 PF13855.6 AIO01674.1 - 1.3e-14 53.7 20.0 5.7e-07 29.2 4.2 2.8 1 1 2 3 3 3 3 Leucine rich repeat LRR_4 PF12799.7 AIO01674.1 - 7.9e-09 35.7 3.5 0.00062 20.1 0.2 2.8 3 0 0 3 3 3 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 AIO01674.1 - 2.1e-06 27.5 5.6 0.38 11.5 0.2 4.6 5 0 0 5 5 5 3 Leucine Rich Repeat FNIP PF05725.12 AIO01674.1 - 0.012 15.7 4.0 3 8.1 2.6 3.7 1 1 1 2 2 2 0 FNIP Repeat LRR_6 PF13516.6 AIO01674.1 - 1.3 9.3 8.8 49 4.3 0.1 4.2 4 0 0 4 4 4 0 Leucine Rich repeat LRR_8 PF13855.6 AIO01675.1 - 3.4e-17 62.0 3.0 0.00076 19.2 0.4 5.5 5 0 0 5 5 5 4 Leucine rich repeat LRR_4 PF12799.7 AIO01675.1 - 3.2e-10 40.1 8.0 0.006 17.0 0.5 6.1 4 2 1 6 6 6 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 AIO01675.1 - 0.036 14.6 5.1 83 4.4 0.1 6.8 8 0 0 8 8 8 0 Leucine Rich Repeat DUF5345 PF17280.2 AIO01675.1 - 0.14 12.1 0.1 0.28 11.2 0.1 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5345) PIP5K PF01504.18 AIO01677.1 - 3.9e-59 200.1 0.0 1.2e-58 198.6 0.0 1.8 1 1 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase DUF4763 PF15960.5 AIO01677.1 - 1.1 8.5 10.0 0.3 10.4 0.9 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4763) WD40 PF00400.32 AIO01678.1 - 8.4e-08 32.8 18.3 0.00052 20.8 1.9 6.7 7 0 0 7 7 7 3 WD domain, G-beta repeat Keratin PF02422.16 AIO01678.1 - 0.0071 16.0 0.4 0.0071 16.0 0.4 2.9 3 0 0 3 3 3 1 Keratin Nucleoporin_N PF08801.11 AIO01678.1 - 0.11 11.2 0.0 1.9 7.1 0.0 2.5 3 0 0 3 3 3 0 Nup133 N terminal like Snf7 PF03357.21 AIO01679.1 - 1.4e-40 138.7 19.8 1.6e-40 138.5 19.8 1.0 1 0 0 1 1 1 1 Snf7 XRN_M PF17846.1 AIO01679.1 - 0.056 12.4 7.9 0.077 11.9 7.9 1.1 1 0 0 1 1 1 0 Xrn1 helical domain Hydantoinase_B PF02538.14 AIO01679.1 - 0.1 11.0 1.5 0.12 10.7 1.5 1.1 1 0 0 1 1 1 0 Hydantoinase B/oxoprolinase Ndr PF03096.14 AIO01679.1 - 0.11 11.2 2.8 0.14 10.9 2.8 1.1 1 0 0 1 1 1 0 Ndr family NPV_P10 PF05531.12 AIO01679.1 - 0.11 13.0 9.9 0.046 14.2 4.2 2.7 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein Rotamase_2 PF13145.6 AIO01679.1 - 0.12 13.2 2.2 0.2 12.5 2.2 1.4 1 0 0 1 1 1 0 PPIC-type PPIASE domain FlaC_arch PF05377.11 AIO01679.1 - 0.33 11.4 4.0 15 6.1 0.8 3.0 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) DUF3573 PF12097.8 AIO01679.1 - 0.49 9.2 4.6 0.63 8.8 4.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) Activator_LAG-3 PF11498.8 AIO01679.1 - 2.5 7.0 18.6 3 6.7 18.6 1.1 1 0 0 1 1 1 0 Transcriptional activator LAG-3 Ribosomal_L18A PF01775.17 AIO01681.1 - 3.4e-40 136.9 1.2 4.5e-40 136.5 1.2 1.2 1 0 0 1 1 1 1 Ribosomal proteins 50S-L18Ae/60S-L20/60S-L18A Nup35_RRM_2 PF14605.6 AIO01684.1 - 1.6e-13 50.4 0.0 2.6e-13 49.7 0.0 1.3 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif Glyco_hydro_32N PF00251.20 AIO01685.1 - 5.8e-54 183.7 6.8 1.1e-53 182.8 6.8 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 N-terminal domain Glyco_hydro_32C PF08244.12 AIO01685.1 - 6.2e-15 55.5 0.0 2.9e-14 53.4 0.0 2.0 1 1 0 1 1 1 1 Glycosyl hydrolases family 32 C terminal PAN_4 PF14295.6 AIO01685.1 - 2e-05 24.4 2.0 5.9e-05 22.9 2.0 1.8 1 0 0 1 1 1 1 PAN domain zf-RING_2 PF13639.6 AIO01686.1 - 0.008 16.5 10.4 0.008 16.5 10.4 3.1 4 0 0 4 4 4 1 Ring finger domain zf-C3HC4_2 PF13923.6 AIO01686.1 - 0.0083 15.9 9.0 0.0083 15.9 9.0 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.6 AIO01686.1 - 0.095 12.6 9.5 0.014 15.3 4.8 2.0 2 0 0 2 2 2 0 zf-RING of BARD1-type protein zf-RING_UBOX PF13445.6 AIO01686.1 - 0.46 10.6 11.6 0.092 12.8 7.2 2.2 2 0 0 2 2 2 0 RING-type zinc-finger zf-C3HC4 PF00097.25 AIO01686.1 - 0.83 9.6 15.2 0.087 12.7 9.4 2.3 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) DUF1272 PF06906.11 AIO01686.1 - 1.3 9.2 8.9 0.92 9.6 5.8 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1272) zf-rbx1 PF12678.7 AIO01686.1 - 1.3 9.4 10.8 0.59 10.5 5.3 2.7 2 0 0 2 2 2 0 RING-H2 zinc finger domain Prok-RING_4 PF14447.6 AIO01686.1 - 2.5 8.1 13.2 1 9.2 9.1 2.5 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 AIO01686.1 - 5.4 7.3 15.2 0.082 13.1 7.6 1.9 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING HEAT PF02985.22 AIO01687.1 - 7.6 7.1 12.7 78 3.9 0.0 7.1 6 0 0 6 6 6 0 HEAT repeat TPR_12 PF13424.6 AIO01689.1 - 3.7e-59 196.9 40.1 5.1e-14 52.3 1.5 8.4 5 3 2 8 8 8 8 Tetratricopeptide repeat TPR_10 PF13374.6 AIO01689.1 - 8.1e-42 140.0 25.8 3.3e-06 26.8 0.2 12.3 12 0 0 12 12 12 9 Tetratricopeptide repeat TPR_2 PF07719.17 AIO01689.1 - 2.8e-21 73.9 42.2 0.0043 17.1 0.1 12.3 12 1 0 12 12 12 6 Tetratricopeptide repeat TPR_1 PF00515.28 AIO01689.1 - 1e-19 69.4 40.6 5.1e-05 22.9 0.0 12.2 13 0 0 13 13 13 6 Tetratricopeptide repeat TPR_8 PF13181.6 AIO01689.1 - 1.1e-19 68.9 36.6 0.044 14.0 0.0 12.3 13 0 0 13 13 13 6 Tetratricopeptide repeat TPR_7 PF13176.6 AIO01689.1 - 2.7e-16 58.3 21.3 0.001 18.9 0.1 9.9 11 0 0 11 11 11 4 Tetratricopeptide repeat TPR_16 PF13432.6 AIO01689.1 - 8e-13 48.8 23.7 0.0041 17.7 0.1 8.2 6 2 1 8 8 8 3 Tetratricopeptide repeat TPR_MalT PF17874.1 AIO01689.1 - 4.3e-08 32.9 15.2 0.0024 17.3 5.9 4.0 2 1 3 5 5 5 4 MalT-like TPR region TPR_14 PF13428.6 AIO01689.1 - 1.4e-07 31.7 30.5 4.5 8.4 0.0 11.2 9 2 3 12 12 12 1 Tetratricopeptide repeat TPR_19 PF14559.6 AIO01689.1 - 2.2e-07 31.3 22.9 0.01 16.3 0.4 7.3 8 0 0 8 8 8 2 Tetratricopeptide repeat SHNi-TPR PF10516.9 AIO01689.1 - 0.0063 15.9 0.1 37 3.9 0.0 4.4 5 0 0 5 5 5 0 SHNi-TPR SET_assoc PF11767.8 AIO01689.1 - 0.023 14.3 0.0 0.061 13.0 0.0 1.7 1 0 0 1 1 1 0 Histone lysine methyltransferase SET associated ANAPC5 PF12862.7 AIO01689.1 - 0.064 13.3 16.2 3.4 7.8 0.2 6.1 4 2 2 6 6 6 0 Anaphase-promoting complex subunit 5 TPR_17 PF13431.6 AIO01689.1 - 1.7 9.2 19.7 16 6.2 0.1 7.5 8 1 0 8 8 7 0 Tetratricopeptide repeat ANAPC3 PF12895.7 AIO01689.1 - 2 8.7 36.2 0.43 10.8 0.7 7.6 4 4 4 8 8 8 0 Anaphase-promoting complex, cyclosome, subunit 3 DUF3856 PF12968.7 AIO01689.1 - 3.9 7.5 8.4 5.8 7.0 2.0 3.6 3 2 1 4 4 3 0 Domain of Unknown Function (DUF3856) TPR_11 PF13414.6 AIO01689.1 - 5.3 6.8 12.7 27 4.6 0.0 5.9 6 1 1 7 7 7 0 TPR repeat ATP-synt_D PF01813.17 AIO01690.1 - 1.3e-72 243.8 1.2 1.3e-72 243.8 1.2 1.3 2 0 0 2 2 2 1 ATP synthase subunit D Exo_endo_phos PF03372.23 AIO01691.1 - 1.9e-06 27.6 0.0 3.2e-06 26.8 0.0 1.5 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family SET PF00856.28 AIO01693.1 - 1.1e-11 45.4 1.0 3.7e-07 30.7 0.2 3.3 2 1 0 2 2 2 2 SET domain MAJIN PF15077.6 AIO01693.1 - 0.18 11.6 0.3 0.36 10.6 0.3 1.5 1 0 0 1 1 1 0 Membrane-anchored junction protein DUF4670 PF15709.5 AIO01693.1 - 1.1 8.5 8.1 2.3 7.5 8.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4670) FHA PF00498.26 AIO01694.1 - 0.0038 17.5 0.0 0.0084 16.4 0.0 1.7 1 1 0 1 1 1 1 FHA domain PA28_beta PF02252.18 AIO01695.1 - 8.6e-11 41.7 0.0 1.3e-05 25.0 0.0 2.3 2 0 0 2 2 2 2 Proteasome activator pa28 beta subunit CBS PF00571.28 AIO01696.1 - 8.4e-17 61.4 0.6 0.00017 21.9 0.0 4.3 4 0 0 4 4 4 4 CBS domain RrnaAD PF00398.20 AIO01697.1 - 1.6e-25 89.7 0.0 3.2e-15 55.9 0.0 2.0 2 0 0 2 2 2 2 Ribosomal RNA adenine dimethylase Methyltransf_12 PF08242.12 AIO01697.1 - 0.0017 19.1 0.0 0.0042 17.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain DOT1 PF08123.13 AIO01697.1 - 0.15 11.6 0.0 0.23 10.9 0.0 1.3 1 0 0 1 1 1 0 Histone methylation protein DOT1 Actin PF00022.19 AIO01698.1 - 1.7e-58 198.1 0.0 1.7e-45 155.4 0.0 2.0 2 0 0 2 2 2 2 Actin Ski2_N PF17911.1 AIO01700.1 - 0.0031 17.3 0.2 0.0099 15.7 0.2 1.9 1 0 0 1 1 1 1 Ski2 N-terminal region Aminotran_1_2 PF00155.21 AIO01701.1 - 1.6e-66 225.0 0.0 1.8e-66 224.8 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II FAD_binding_2 PF00890.24 AIO01702.1 - 2.2e-84 284.0 0.1 3.2e-84 283.4 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain ApbE PF02424.15 AIO01702.1 - 2.5e-48 164.9 0.0 1.2e-47 162.7 0.0 2.0 1 1 0 1 1 1 1 ApbE family NAD_binding_1 PF00175.21 AIO01702.1 - 1.3e-16 61.2 0.0 2.6e-16 60.2 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain DAO PF01266.24 AIO01702.1 - 3.4e-13 49.9 1.1 9.4e-13 48.5 1.0 1.7 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_oxidored PF12831.7 AIO01702.1 - 1.7e-09 37.5 5.3 4.5e-09 36.2 4.9 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_6 PF00970.24 AIO01702.1 - 5.1e-09 36.4 0.0 1.2e-08 35.2 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain Pyr_redox_2 PF07992.14 AIO01702.1 - 1.7e-08 34.0 0.1 5.3e-08 32.4 0.1 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 AIO01702.1 - 4.9e-07 29.9 1.8 2.1e-06 27.8 1.8 2.2 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.22 AIO01702.1 - 2.4e-06 26.9 5.7 1.7e-05 24.1 5.2 2.3 2 0 0 2 2 2 1 Glucose inhibited division protein A AlaDh_PNT_C PF01262.21 AIO01702.1 - 1e-05 24.9 1.1 2.1e-05 24.0 1.1 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain HI0933_like PF03486.14 AIO01702.1 - 0.00025 19.9 4.9 0.0011 17.8 4.0 2.3 2 0 0 2 2 2 1 HI0933-like protein NAD_binding_6 PF08030.12 AIO01702.1 - 0.004 17.3 0.0 0.052 13.7 0.0 2.3 2 0 0 2 2 2 1 Ferric reductase NAD binding domain Pyr_redox PF00070.27 AIO01702.1 - 0.0066 17.0 1.4 0.02 15.4 1.4 1.8 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 AIO01702.1 - 0.0067 15.7 1.3 0.055 12.7 1.4 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 AIO01702.1 - 0.041 12.9 1.3 0.077 12.0 1.3 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein FAD_binding_3 PF01494.19 AIO01702.1 - 0.23 10.7 2.1 0.38 9.9 2.1 1.3 1 0 0 1 1 1 0 FAD binding domain DUF2838 PF10998.8 AIO01704.1 - 8.8e-15 54.9 21.2 3.9e-09 36.7 6.5 3.4 3 0 0 3 3 3 2 Protein of unknown function (DUF2838) Telomere_reg-2 PF10193.9 AIO01706.1 - 0.00025 21.5 0.0 0.0086 16.5 0.0 2.9 2 0 0 2 2 2 1 Telomere length regulation protein Pex19 PF04614.12 AIO01706.1 - 0.11 12.3 0.2 0.17 11.6 0.2 1.3 1 0 0 1 1 1 0 Pex19 protein family VWA_2 PF13519.6 AIO01707.1 - 0.16 12.6 0.6 0.55 10.9 0.0 2.1 2 0 0 2 2 2 0 von Willebrand factor type A domain IFT20 PF14931.6 AIO01707.1 - 0.54 10.4 4.6 1.4 9.1 2.8 2.4 2 0 0 2 2 2 0 Intraflagellar transport complex B, subunit 20 Arabinose_Isome PF02610.15 AIO01708.1 - 0.012 14.9 0.3 0.021 14.1 0.3 1.4 1 0 0 1 1 1 0 L-arabinose isomerase GP120 PF00516.18 AIO01708.1 - 0.02 13.5 0.5 0.027 13.1 0.5 1.3 1 1 0 1 1 1 0 Envelope glycoprotein GP120 UPF0203 PF05254.12 AIO01708.1 - 0.028 14.6 1.1 0.2 12.0 1.1 2.2 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0203) Ntox27 PF15531.6 AIO01709.1 - 0.14 12.1 0.7 0.28 11.1 0.7 1.4 1 0 0 1 1 1 0 Bacterial toxin 27 Phostensin PF13914.6 AIO01712.1 - 0.21 12.2 1.0 0.43 11.2 0.1 1.9 1 1 1 2 2 2 0 Phostensin PP1-binding and SH3-binding region PhrC_PhrF PF11131.8 AIO01712.1 - 0.37 10.4 7.7 1.7 8.3 0.0 2.9 3 0 0 3 3 3 0 Rap-phr extracellular signalling PSP1 PF04468.12 AIO01714.1 - 3.8e-23 81.6 0.3 8.5e-23 80.5 0.3 1.6 1 0 0 1 1 1 1 PSP1 C-terminal conserved region Cupin_8 PF13621.6 AIO01715.1 - 0.04 13.6 0.0 0.22 11.2 0.0 2.0 2 0 0 2 2 2 0 Cupin-like domain Invasin_D3 PF09134.10 AIO01715.1 - 3.2 8.1 5.2 9.4 6.6 0.0 3.1 4 0 0 4 4 4 0 Invasin, domain 3 Pkinase PF00069.25 AIO01717.1 - 2.2e-25 89.5 0.0 2.8e-25 89.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 AIO01717.1 - 8.6e-15 54.7 0.0 1.2e-14 54.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 AIO01717.1 - 6e-13 48.4 0.2 8.2e-13 47.9 0.2 1.1 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 AIO01717.1 - 5.9e-06 26.4 0.1 9.9e-06 25.6 0.1 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 AIO01717.1 - 0.013 14.9 0.1 0.021 14.2 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.25 AIO01718.1 - 1.3e-24 87.0 0.0 1.9e-24 86.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 AIO01718.1 - 4.5e-13 49.1 0.0 5.7e-13 48.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 AIO01718.1 - 1e-08 34.4 0.0 1.3e-08 34.0 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 AIO01718.1 - 0.0001 22.3 0.0 0.00024 21.1 0.0 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 AIO01718.1 - 0.0081 15.5 0.0 0.014 14.8 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family zf-CCCH PF00642.24 AIO01719.1 - 9.1e-05 22.3 6.3 0.00018 21.4 6.3 1.5 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 AIO01719.1 - 1.7 8.8 6.1 3.5 7.8 6.1 1.6 1 0 0 1 1 1 0 Zinc finger domain Cupin_5 PF06172.11 AIO01720.1 - 2.6e-41 141.1 0.0 3.5e-41 140.7 0.0 1.2 1 0 0 1 1 1 1 Cupin superfamily (DUF985) zf-CCCH PF00642.24 AIO01721.1 - 1e-06 28.5 1.0 1e-06 28.5 1.0 2.9 3 0 0 3 3 3 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 AIO01721.1 - 0.00026 20.9 0.8 0.00071 19.6 0.8 1.8 1 0 0 1 1 1 1 Zinc finger domain zf-CCCH_2 PF14608.6 AIO01721.1 - 0.017 15.6 0.6 0.044 14.3 0.6 1.8 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger zf-CCCH_4 PF18044.1 AIO01721.1 - 0.061 13.1 1.2 0.16 11.8 1.2 1.8 1 0 0 1 1 1 0 CCCH-type zinc finger Pkinase PF00069.25 AIO01722.1 - 4.1e-63 213.2 0.1 1.5e-62 211.3 0.1 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 AIO01722.1 - 2.6e-22 79.3 0.1 1.6e-21 76.8 0.1 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 AIO01722.1 - 4.6e-06 26.2 0.2 0.057 12.7 0.2 3.0 2 1 0 3 3 3 2 Kinase-like Kdo PF06293.14 AIO01722.1 - 0.0015 17.9 0.1 0.0027 17.1 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 AIO01722.1 - 0.032 13.0 0.0 0.048 12.4 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase YrbL-PhoP_reg PF10707.9 AIO01722.1 - 0.033 13.7 0.5 2.5 7.6 0.2 2.6 3 0 0 3 3 3 0 PhoP regulatory network protein YrbL FTA2 PF13095.6 AIO01722.1 - 0.039 13.6 0.3 0.24 11.0 0.1 2.3 2 1 1 3 3 3 0 Kinetochore Sim4 complex subunit FTA2 CDC45 PF02724.14 AIO01724.1 - 0.12 10.7 2.1 0.18 10.1 2.1 1.2 1 0 0 1 1 1 0 CDC45-like protein Kri1 PF05178.12 AIO01725.1 - 2.3e-19 69.8 9.7 2.3e-19 69.8 9.7 4.9 5 0 0 5 5 5 1 KRI1-like family Kri1_C PF12936.7 AIO01725.1 - 4.9e-19 68.3 1.4 1.1e-18 67.2 0.0 2.4 2 0 0 2 2 2 1 KRI1-like family C-terminal Rdx PF10262.9 AIO01727.1 - 1.4e-14 54.0 0.0 3.2e-14 52.9 0.0 1.6 1 0 0 1 1 1 1 Rdx family PPO1_KFDV PF12143.8 AIO01727.1 - 0.17 12.0 1.1 0.3 11.2 1.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF_B2219) STT3 PF02516.14 AIO01728.1 - 1.7e-19 70.1 10.3 2e-19 69.9 10.3 1.2 1 0 0 1 1 1 1 Oligosaccharyl transferase STT3 subunit STT3 PF02516.14 AIO01729.1 - 0.0019 17.2 0.0 0.0034 16.4 0.0 1.4 1 1 0 1 1 1 1 Oligosaccharyl transferase STT3 subunit DUF1358 PF07096.11 AIO01729.1 - 0.15 12.0 0.6 0.28 11.2 0.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1358) Rhodanese PF00581.20 AIO01730.1 - 4e-09 36.9 0.0 1.1e-08 35.6 0.0 1.7 2 0 0 2 2 2 1 Rhodanese-like domain DUF2437 PF10370.9 AIO01730.1 - 0.14 13.1 0.1 29 5.7 0.0 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF2437) ApbE PF02424.15 AIO01731.1 - 4.3e-57 193.6 0.0 6.3e-57 193.0 0.0 1.2 1 0 0 1 1 1 1 ApbE family FAD_binding_2 PF00890.24 AIO01731.1 - 3.8e-30 105.3 0.5 6e-30 104.7 0.5 1.3 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.7 AIO01731.1 - 1.4e-08 34.5 4.3 2.3e-08 33.8 4.3 1.5 1 1 0 1 1 1 1 FAD dependent oxidoreductase DAO PF01266.24 AIO01731.1 - 1.6e-08 34.6 0.4 3.1e-08 33.6 0.4 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 AIO01731.1 - 6.7e-07 29.4 2.3 2.3e-06 27.7 1.1 2.5 2 1 1 3 3 3 1 NAD(P)-binding Rossmann-like domain AlaDh_PNT_C PF01262.21 AIO01731.1 - 2.5e-06 26.9 1.4 5.2e-06 25.9 1.4 1.5 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox_2 PF07992.14 AIO01731.1 - 8.3e-06 25.2 0.1 1.7e-05 24.2 0.1 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 AIO01731.1 - 1.3e-05 24.5 5.1 1.7e-05 24.1 3.8 1.8 2 0 0 2 2 2 1 Glucose inhibited division protein A HI0933_like PF03486.14 AIO01731.1 - 0.00032 19.5 2.9 0.00057 18.7 2.9 1.4 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox PF00070.27 AIO01731.1 - 0.0007 20.1 2.7 0.0011 19.5 0.5 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 AIO01731.1 - 0.0019 17.5 0.7 0.0032 16.8 0.7 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.6 AIO01731.1 - 0.0022 17.3 0.1 0.0045 16.3 0.1 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 AIO01731.1 - 0.029 13.6 3.4 0.064 12.5 0.8 2.5 3 0 0 3 3 3 0 Thi4 family Lycopene_cycl PF05834.12 AIO01731.1 - 0.15 11.1 1.4 0.24 10.4 1.4 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein NAD_binding_1 PF00175.21 AIO01732.1 - 3e-19 69.7 0.0 4e-19 69.3 0.0 1.2 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 AIO01732.1 - 6.8e-09 36.0 0.0 1.2e-08 35.2 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.12 AIO01732.1 - 2.3e-08 34.3 0.0 0.00025 21.2 0.0 2.3 2 0 0 2 2 2 2 Ferric reductase NAD binding domain HA2 PF04408.23 AIO01733.1 - 9.1e-19 67.7 0.0 2.8e-18 66.2 0.0 1.8 2 0 0 2 2 2 1 Helicase associated domain (HA2) Helicase_C PF00271.31 AIO01733.1 - 1.9e-14 53.9 0.0 5.5e-14 52.4 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain OB_NTP_bind PF07717.16 AIO01733.1 - 4.4e-14 52.6 0.1 1e-13 51.4 0.1 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold DEAD PF00270.29 AIO01733.1 - 1.2e-08 34.9 0.1 5.9e-08 32.7 0.1 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_22 PF13401.6 AIO01733.1 - 1.2e-06 28.9 0.1 3e-06 27.6 0.1 1.6 1 0 0 1 1 1 1 AAA domain AAA_7 PF12775.7 AIO01733.1 - 0.00037 20.1 0.0 0.0012 18.3 0.0 1.9 1 0 0 1 1 1 1 P-loop containing dynein motor region T2SSE PF00437.20 AIO01733.1 - 0.00075 18.6 0.0 0.0016 17.5 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_19 PF13245.6 AIO01733.1 - 0.001 19.4 0.0 0.0025 18.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain ResIII PF04851.15 AIO01733.1 - 0.0031 17.6 0.0 0.29 11.1 0.0 2.4 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_30 PF13604.6 AIO01733.1 - 0.0082 15.9 0.0 0.021 14.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.27 AIO01733.1 - 0.038 14.5 0.2 1.1 9.8 0.1 2.4 1 1 0 2 2 2 0 ABC transporter Sigma54_activat PF00158.26 AIO01733.1 - 0.066 12.9 0.0 0.51 10.0 0.0 2.1 2 0 0 2 2 2 0 Sigma-54 interaction domain SRP54 PF00448.22 AIO01733.1 - 0.096 12.3 0.0 0.2 11.3 0.0 1.5 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_16 PF13191.6 AIO01733.1 - 0.12 12.8 0.2 0.55 10.6 0.2 2.1 1 1 0 1 1 1 0 AAA ATPase domain Armet PF10208.9 AIO01734.1 - 5.2e-08 32.9 0.0 1.1e-07 31.9 0.0 1.5 1 0 0 1 1 1 1 Degradation arginine-rich protein for mis-folding SAP PF02037.27 AIO01734.1 - 0.0032 17.2 0.1 0.0075 16.0 0.1 1.7 1 0 0 1 1 1 1 SAP domain adh_short PF00106.25 AIO01735.1 - 8.2e-47 159.2 1.0 1e-46 158.9 1.0 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 AIO01735.1 - 3.8e-33 115.0 0.7 4.8e-33 114.7 0.7 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 AIO01735.1 - 9.2e-12 45.2 0.1 1.2e-11 44.9 0.1 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 AIO01735.1 - 0.0029 17.1 0.1 0.0063 16.0 0.1 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 AIO01735.1 - 0.012 15.1 0.3 1.2 8.4 0.0 2.2 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase QRPTase_C PF01729.19 AIO01735.1 - 0.032 14.0 0.1 0.05 13.4 0.1 1.3 1 0 0 1 1 1 0 Quinolinate phosphoribosyl transferase, C-terminal domain Polysacc_synt_2 PF02719.15 AIO01735.1 - 0.058 12.5 0.4 0.08 12.1 0.4 1.6 1 1 0 1 1 1 0 Polysaccharide biosynthesis protein DUF871 PF05913.11 AIO01735.1 - 0.22 10.7 0.0 0.31 10.2 0.0 1.3 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF871) adh_short PF00106.25 AIO01736.1 - 4e-36 124.3 0.0 1e-35 123.0 0.0 1.6 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 AIO01736.1 - 4.4e-20 72.2 0.0 1.3e-19 70.7 0.0 1.7 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 AIO01736.1 - 3.2e-05 23.9 0.1 6.5e-05 22.9 0.0 1.5 2 0 0 2 2 2 1 KR domain Epimerase PF01370.21 AIO01736.1 - 0.00046 19.7 0.2 0.0029 17.1 0.2 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family HTH_Tnp_Tc3_1 PF11427.8 AIO01737.1 - 0.39 10.6 2.1 1.8 8.5 0.3 3.1 3 0 0 3 3 3 0 Tc3 transposase Glutaredoxin PF00462.24 AIO01738.1 - 3.2e-18 65.7 3.2 1.4e-13 50.8 0.1 3.1 3 0 0 3 3 3 2 Glutaredoxin Thioredoxin PF00085.20 AIO01738.1 - 9.2e-14 51.3 0.3 1.8e-13 50.4 0.2 1.6 2 0 0 2 2 2 1 Thioredoxin OST3_OST6 PF04756.13 AIO01738.1 - 0.00063 19.2 0.0 0.00085 18.8 0.0 1.2 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin_7 PF13899.6 AIO01738.1 - 0.0024 18.0 0.1 0.0047 17.1 0.1 1.5 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_8 PF13905.6 AIO01738.1 - 0.0074 16.6 0.0 0.019 15.3 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin-like Redoxin PF08534.10 AIO01738.1 - 0.0099 15.6 0.2 0.02 14.6 0.2 1.5 1 0 0 1 1 1 1 Redoxin Thioredoxin_6 PF13848.6 AIO01738.1 - 0.03 14.2 0.0 0.066 13.1 0.0 1.5 1 0 0 1 1 1 0 Thioredoxin-like domain AhpC-TSA PF00578.21 AIO01738.1 - 0.057 13.3 0.1 0.094 12.6 0.1 1.5 1 0 0 1 1 1 0 AhpC/TSA family Thioredoxin_2 PF13098.6 AIO01738.1 - 0.11 13.0 0.4 0.52 10.8 0.1 2.1 2 1 0 2 2 2 0 Thioredoxin-like domain AAA PF00004.29 AIO01739.1 - 6.4e-36 123.7 0.0 1.6e-35 122.4 0.0 1.6 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 AIO01739.1 - 1e-07 32.0 0.0 3.2e-07 30.4 0.0 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 AIO01739.1 - 2.7e-07 30.5 0.0 9.2e-07 28.7 0.0 1.8 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 AIO01739.1 - 5.4e-07 30.1 0.1 2.2e-05 24.9 0.1 2.5 1 1 1 2 2 2 1 AAA ATPase domain AAA_lid_3 PF17862.1 AIO01739.1 - 1.9e-06 27.6 0.0 4.7e-06 26.3 0.0 1.7 1 0 0 1 1 1 1 AAA+ lid domain TIP49 PF06068.13 AIO01739.1 - 2.1e-06 27.2 0.0 1.2e-05 24.8 0.0 2.0 1 1 1 2 2 2 1 TIP49 P-loop domain AAA_22 PF13401.6 AIO01739.1 - 7.5e-06 26.3 0.3 0.0014 18.9 0.0 2.7 2 1 0 3 3 2 1 AAA domain AAA_33 PF13671.6 AIO01739.1 - 1.4e-05 25.2 0.0 3.1e-05 24.2 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.6 AIO01739.1 - 5.9e-05 23.6 0.0 0.00011 22.8 0.0 1.6 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 AIO01739.1 - 0.00021 21.1 0.0 0.00035 20.4 0.0 1.4 1 1 0 1 1 1 1 IstB-like ATP binding protein RNA_helicase PF00910.22 AIO01739.1 - 0.00048 20.5 0.0 0.001 19.4 0.0 1.6 1 1 0 1 1 1 1 RNA helicase AAA_14 PF13173.6 AIO01739.1 - 0.0012 18.9 0.0 0.0022 18.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain TsaE PF02367.17 AIO01739.1 - 0.0018 18.3 0.0 0.0033 17.4 0.0 1.4 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE Zeta_toxin PF06414.12 AIO01739.1 - 0.002 17.5 0.1 0.0061 15.9 0.0 1.8 2 0 0 2 2 2 1 Zeta toxin AAA_24 PF13479.6 AIO01739.1 - 0.0024 17.6 0.0 0.0043 16.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_7 PF12775.7 AIO01739.1 - 0.0025 17.4 0.0 0.012 15.2 0.0 2.1 2 1 0 2 2 2 1 P-loop containing dynein motor region Mg_chelatase PF01078.21 AIO01739.1 - 0.0032 16.9 0.0 0.0065 15.9 0.0 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_28 PF13521.6 AIO01739.1 - 0.0033 17.7 0.2 0.009 16.3 0.0 1.8 2 0 0 2 2 1 1 AAA domain SKI PF01202.22 AIO01739.1 - 0.0039 17.3 0.0 0.015 15.4 0.0 1.9 2 0 0 2 2 2 1 Shikimate kinase AAA_3 PF07726.11 AIO01739.1 - 0.0039 17.0 0.0 0.013 15.4 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_2 PF07724.14 AIO01739.1 - 0.0096 16.1 0.0 0.02 15.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) Sigma54_activat PF00158.26 AIO01739.1 - 0.011 15.5 0.0 0.038 13.7 0.0 1.9 2 1 0 2 2 2 0 Sigma-54 interaction domain Rad17 PF03215.15 AIO01739.1 - 0.012 15.6 0.0 0.02 14.8 0.0 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain NACHT PF05729.12 AIO01739.1 - 0.017 15.0 0.0 0.036 14.0 0.0 1.6 1 1 0 1 1 1 0 NACHT domain Sigma54_activ_2 PF14532.6 AIO01739.1 - 0.018 15.2 0.0 0.064 13.4 0.0 1.9 2 0 0 2 2 1 0 Sigma-54 interaction domain Parvo_NS1 PF01057.17 AIO01739.1 - 0.021 13.9 0.0 0.038 13.1 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Cytidylate_kin PF02224.18 AIO01739.1 - 0.022 14.5 0.1 0.082 12.6 0.0 1.9 2 0 0 2 2 2 0 Cytidylate kinase AAA_29 PF13555.6 AIO01739.1 - 0.029 14.1 0.0 0.081 12.7 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_25 PF13481.6 AIO01739.1 - 0.031 13.9 0.2 0.16 11.5 0.1 2.1 2 1 0 3 3 2 0 AAA domain DUF815 PF05673.13 AIO01739.1 - 0.038 13.1 0.0 0.1 11.8 0.0 1.9 2 1 0 2 2 1 0 Protein of unknown function (DUF815) AAA_11 PF13086.6 AIO01739.1 - 0.052 13.3 0.0 0.082 12.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.6 AIO01739.1 - 0.055 13.9 0.0 0.11 12.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 AIO01739.1 - 0.072 13.6 0.1 1.7 9.2 0.0 2.5 1 1 2 3 3 2 0 ABC transporter AAA_6 PF12774.7 AIO01739.1 - 0.073 12.0 0.0 0.12 11.3 0.0 1.3 1 0 0 1 1 1 0 Hydrolytic ATP binding site of dynein motor region PhoH PF02562.16 AIO01739.1 - 0.076 12.5 0.0 0.15 11.5 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein PPV_E1_C PF00519.17 AIO01739.1 - 0.084 11.7 0.0 0.15 10.9 0.0 1.3 1 0 0 1 1 1 0 Papillomavirus helicase DUF2075 PF09848.9 AIO01739.1 - 0.15 11.3 0.0 0.22 10.7 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) MMR_HSR1 PF01926.23 AIO01739.1 - 0.17 12.0 0.1 1.6 8.8 0.0 2.3 2 1 0 2 2 2 0 50S ribosome-binding GTPase 2OG-FeII_Oxy_2 PF13532.6 AIO01741.1 - 2.9e-08 34.1 0.0 4.2e-08 33.6 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.20 AIO01741.1 - 0.021 15.3 0.0 0.12 12.8 0.0 2.1 2 0 0 2 2 2 0 2OG-Fe(II) oxygenase superfamily ORC_WH_C PF18137.1 AIO01742.1 - 0.055 13.6 2.5 1.1 9.4 0.0 2.1 2 0 0 2 2 2 0 Origin recognition complex winged helix C-terminal DUF3464 PF11947.8 AIO01742.1 - 1.7 8.4 4.4 8.6 6.1 1.9 2.2 2 0 0 2 2 2 0 Photosynthesis affected mutant 68 UQ_con PF00179.26 AIO01743.1 - 9.1e-55 184.2 0.0 1e-54 184.0 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 AIO01743.1 - 0.0063 16.8 0.0 0.0074 16.6 0.0 1.3 1 0 0 1 1 1 1 RWD domain Prok-E2_B PF14461.6 AIO01743.1 - 0.14 11.9 0.0 0.16 11.7 0.0 1.2 1 0 0 1 1 1 0 Prokaryotic E2 family B CENP-T_C PF15511.6 AIO01744.1 - 1e-05 25.6 0.1 1.7e-05 24.9 0.0 1.3 1 1 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold TAF PF02969.17 AIO01744.1 - 0.00056 20.0 0.1 0.00088 19.4 0.1 1.3 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.23 AIO01744.1 - 0.00058 20.1 0.4 0.00081 19.6 0.0 1.4 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.13 AIO01744.1 - 0.0025 17.8 0.0 0.0029 17.6 0.0 1.2 1 0 0 1 1 1 1 Bromodomain associated Histone PF00125.24 AIO01744.1 - 0.0042 17.4 1.7 0.0082 16.5 1.7 1.5 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID-31kDa PF02291.15 AIO01744.1 - 0.063 13.3 0.0 0.083 13.0 0.0 1.2 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Thioredoxin PF00085.20 AIO01746.1 - 3.3e-14 52.7 0.0 9.4e-14 51.3 0.0 1.8 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 AIO01746.1 - 0.0075 16.7 0.8 0.097 13.1 0.3 2.8 2 1 0 2 2 2 1 Thioredoxin-like domain Thioredoxin_3 PF13192.6 AIO01746.1 - 0.033 14.2 0.0 15 5.7 0.0 2.9 2 0 0 2 2 2 0 Thioredoxin domain Thioredoxin_6 PF13848.6 AIO01746.1 - 0.047 13.6 0.1 4.2 7.2 0.0 2.7 2 1 0 2 2 2 0 Thioredoxin-like domain Thioredoxin_8 PF13905.6 AIO01746.1 - 0.092 13.1 0.1 0.53 10.6 0.1 2.4 2 1 0 2 2 2 0 Thioredoxin-like OST3_OST6 PF04756.13 AIO01746.1 - 0.11 11.8 0.1 0.27 10.5 0.1 1.6 1 0 0 1 1 1 0 OST3 / OST6 family, transporter family Endonuc_subdom PF09062.10 AIO01746.1 - 0.13 13.1 0.3 12 6.8 0.1 2.5 2 0 0 2 2 2 0 PI-PfuI Endonuclease subdomain DUF1028 PF06267.12 AIO01747.1 - 0.04 13.7 0.0 0.057 13.2 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF1028) zf-CDGSH PF09360.10 AIO01750.1 - 7e-19 67.8 5.9 9.5e-10 38.5 0.3 2.2 2 0 0 2 2 2 2 Iron-binding zinc finger CDGSH type Peptidase_M16 PF00675.20 AIO01751.1 - 4.8e-27 94.8 0.0 8e-27 94.1 0.0 1.3 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 AIO01751.1 - 3.3e-14 53.3 0.0 6.5e-14 52.4 0.0 1.5 1 0 0 1 1 1 1 Peptidase M16 inactive domain OTU PF02338.19 AIO01752.1 - 9.2e-17 61.7 0.1 1.7e-16 60.9 0.1 1.4 1 0 0 1 1 1 1 OTU-like cysteine protease zf-RanBP PF00641.18 AIO01752.1 - 0.00013 21.2 1.8 0.00013 21.2 1.8 5.0 5 0 0 5 5 5 3 Zn-finger in Ran binding protein and others Peptidase_C65 PF10275.9 AIO01752.1 - 0.00031 20.3 0.0 0.29 10.5 0.0 2.4 1 1 0 2 2 2 2 Peptidase C65 Otubain zf-RRN7 PF11781.8 AIO01752.1 - 0.01 15.5 1.7 0.01 15.5 1.7 3.1 4 0 0 4 4 4 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 zf-tcix PF14952.6 AIO01752.1 - 0.034 13.8 0.3 0.034 13.8 0.3 4.0 3 1 0 3 3 3 0 Putative treble-clef, zinc-finger, Zn-binding zf-ribbon_3 PF13248.6 AIO01752.1 - 0.084 12.3 0.0 0.084 12.3 0.0 4.1 4 0 0 4 4 4 0 zinc-ribbon domain RRM_1 PF00076.22 AIO01753.1 - 1.3e-06 28.1 0.0 0.059 13.2 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Cytochrom_NNT PF03264.14 AIO01753.1 - 0.027 14.2 0.3 0.051 13.3 0.3 1.4 1 0 0 1 1 1 0 NapC/NirT cytochrome c family, N-terminal region tRNA-synt_2b PF00587.25 AIO01754.1 - 5.4e-31 108.0 0.0 7.9e-28 97.6 0.0 2.4 2 0 0 2 2 2 2 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 AIO01754.1 - 8.6e-18 64.3 0.1 2e-17 63.1 0.1 1.7 1 0 0 1 1 1 1 Anticodon binding domain TGS PF02824.21 AIO01754.1 - 1.8e-13 50.3 0.0 4.7e-13 49.0 0.0 1.8 2 0 0 2 2 2 1 TGS domain tRNA_SAD PF07973.14 AIO01754.1 - 2e-11 43.8 0.0 3.5e-11 43.0 0.0 1.4 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain TPR_1 PF00515.28 AIO01755.1 - 8.1e-20 69.8 4.7 1.5e-05 24.6 0.1 6.1 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_2 PF07719.17 AIO01755.1 - 3.2e-18 64.3 6.9 3.6e-05 23.6 0.1 6.7 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_17 PF13431.6 AIO01755.1 - 1.6e-17 62.5 6.7 0.00036 20.7 0.8 5.4 5 0 0 5 5 4 3 Tetratricopeptide repeat TPR_11 PF13414.6 AIO01755.1 - 1.2e-16 60.1 7.8 7.6e-05 22.3 0.0 5.4 3 2 2 5 5 5 3 TPR repeat TPR_14 PF13428.6 AIO01755.1 - 2.2e-15 56.0 10.0 0.00048 20.7 0.0 6.7 3 2 4 7 7 6 4 Tetratricopeptide repeat TPR_19 PF14559.6 AIO01755.1 - 3e-11 43.7 11.7 2.2e-05 24.9 0.1 4.9 5 0 0 5 5 4 3 Tetratricopeptide repeat TPR_16 PF13432.6 AIO01755.1 - 2.2e-10 41.0 5.9 2.1e-06 28.3 0.2 4.5 2 2 3 5 5 5 4 Tetratricopeptide repeat TPR_8 PF13181.6 AIO01755.1 - 2.3e-10 39.9 2.6 0.0086 16.2 0.0 6.4 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_7 PF13176.6 AIO01755.1 - 1.9e-06 27.5 0.2 2.1 8.6 0.0 5.1 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_12 PF13424.6 AIO01755.1 - 5.7e-06 26.5 3.0 0.00042 20.6 0.1 3.7 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_9 PF13371.6 AIO01755.1 - 1.4e-05 25.2 1.4 0.00017 21.7 0.1 3.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_10 PF13374.6 AIO01755.1 - 0.0026 17.6 8.9 2.1 8.4 0.0 4.2 4 0 0 4 4 4 2 Tetratricopeptide repeat BTAD PF03704.17 AIO01755.1 - 0.063 13.7 7.2 0.69 10.3 0.0 3.5 3 1 1 4 4 4 0 Bacterial transcriptional activator domain BRK PF07533.16 AIO01755.1 - 0.093 12.4 0.1 0.27 10.9 0.1 1.8 2 0 0 2 2 1 0 BRK domain Fis1_TPR_C PF14853.6 AIO01755.1 - 0.13 12.4 0.8 4.6 7.4 0.1 3.5 3 0 0 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat TPR_6 PF13174.6 AIO01755.1 - 0.4 11.4 12.7 27 5.7 0.0 6.2 7 0 0 7 7 6 0 Tetratricopeptide repeat ANAPC3 PF12895.7 AIO01755.1 - 1.2 9.5 3.9 2.5 8.4 0.3 2.5 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_20 PF14561.6 AIO01755.1 - 5.6 7.4 21.9 1.9 8.9 0.1 4.9 4 1 2 6 6 4 0 Tetratricopeptide repeat Ribosomal_L2_C PF03947.18 AIO01756.1 - 5.5e-43 146.2 3.5 1.2e-42 145.1 2.1 2.0 2 0 0 2 2 2 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.23 AIO01756.1 - 4.2e-13 49.1 0.1 1.2e-12 47.6 0.1 1.8 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain CCDC-167 PF15188.6 AIO01757.1 - 0.068 13.5 0.3 0.24 11.8 0.3 1.9 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 167 PilJ PF13675.6 AIO01757.1 - 0.16 12.0 9.3 8 6.5 0.1 4.7 4 0 0 4 4 4 0 Type IV pili methyl-accepting chemotaxis transducer N-term Spc7 PF08317.11 AIO01757.1 - 0.32 9.9 1.3 1 8.2 1.3 1.9 1 0 0 1 1 1 0 Spc7 kinetochore protein HAUS-augmin3 PF14932.6 AIO01757.1 - 5.2 6.6 5.9 53 3.3 2.9 2.9 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 3 Sigma70_r4 PF04545.16 AIO01758.1 - 0.0034 16.9 0.0 12 5.5 0.0 3.8 3 0 0 3 3 3 2 Sigma-70, region 4 Mce4_CUP1 PF11887.8 AIO01758.1 - 8.9 5.7 11.0 4.6 6.6 0.5 2.8 2 0 0 2 2 2 0 Cholesterol uptake porter CUP1 of Mce4, putative Choline_kinase PF01633.20 AIO01760.1 - 7.5e-31 107.4 0.0 8.9e-30 103.9 0.0 2.2 1 1 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.23 AIO01760.1 - 1.1e-09 38.6 0.0 4.8e-07 29.9 0.0 3.0 2 1 0 2 2 2 2 Phosphotransferase enzyme family Arginase PF00491.21 AIO01761.1 - 2.2e-72 243.9 0.0 2.6e-72 243.7 0.0 1.0 1 0 0 1 1 1 1 Arginase family zf-CCCH PF00642.24 AIO01763.1 - 8.5e-05 22.4 1.8 0.00018 21.3 1.8 1.6 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) NIF PF03031.18 AIO01763.1 - 0.00057 19.7 0.0 0.0012 18.6 0.0 1.5 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase zf_CCCH_4 PF18345.1 AIO01763.1 - 0.0055 16.7 0.1 0.013 15.5 0.1 1.6 1 0 0 1 1 1 1 Zinc finger domain Rieske PF00355.26 AIO01766.1 - 1.1e-12 47.8 0.0 2.4e-12 46.6 0.0 1.5 1 1 0 1 1 1 1 Rieske [2Fe-2S] domain Methyltransf_23 PF13489.6 AIO01769.1 - 8.4e-19 68.0 0.0 1.3e-18 67.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 AIO01769.1 - 5e-12 46.3 0.0 9.9e-12 45.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 AIO01769.1 - 1.1e-10 42.0 0.0 2.2e-10 41.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 AIO01769.1 - 5.7e-09 35.7 0.0 8e-09 35.2 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.6 AIO01769.1 - 1.7e-07 31.1 0.0 3.5e-07 30.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 AIO01769.1 - 2.2e-07 31.5 0.0 8.6e-07 29.6 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Peptidase_C14 PF00656.22 AIO01770.1 - 4.3e-48 164.4 0.0 5.6e-48 164.0 0.0 1.1 1 0 0 1 1 1 1 Caspase domain Mei5 PF10376.9 AIO01771.1 - 0.0022 17.9 5.0 0.0044 16.9 5.0 1.5 1 0 0 1 1 1 1 Double-strand recombination repair protein DUF2273 PF10031.9 AIO01771.1 - 0.029 14.4 0.1 0.053 13.5 0.1 1.3 1 0 0 1 1 1 0 Small integral membrane protein (DUF2273) Cauli_AT PF03233.13 AIO01771.1 - 0.43 10.5 3.0 0.77 9.7 3.0 1.3 1 0 0 1 1 1 0 Aphid transmission protein DUF1664 PF07889.12 AIO01771.1 - 0.88 9.6 3.7 2.2 8.4 3.7 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) BST2 PF16716.5 AIO01771.1 - 7.4 7.2 10.4 11 6.7 3.9 2.5 1 1 1 2 2 2 0 Bone marrow stromal antigen 2 DUF4034 PF13226.6 AIO01772.1 - 0.037 13.4 5.1 0.024 14.0 1.2 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4034) Laminin_G_3 PF13385.6 AIO01774.1 - 8.8e-13 48.7 0.2 2.4e-12 47.3 0.0 1.9 2 0 0 2 2 2 1 Concanavalin A-like lectin/glucanases superfamily DUF2972 PF11186.8 AIO01774.1 - 0.068 13.1 0.1 0.23 11.4 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2972) Ribosomal_L10 PF00466.20 AIO01774.1 - 0.2 11.8 0.4 1.7 8.8 0.1 2.5 2 0 0 2 2 2 0 Ribosomal protein L10 EF-hand_7 PF13499.6 AIO01775.1 - 0.00039 20.8 0.0 0.00075 19.9 0.0 1.5 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_8 PF13833.6 AIO01775.1 - 0.049 13.5 0.0 12 5.9 0.0 2.3 1 1 1 2 2 2 0 EF-hand domain pair EF-hand_1 PF00036.32 AIO01775.1 - 0.065 12.8 0.0 2.4 7.9 0.0 2.4 2 0 0 2 2 2 0 EF hand EF-hand_6 PF13405.6 AIO01775.1 - 0.086 12.8 0.0 11 6.3 0.0 2.7 3 0 0 3 3 3 0 EF-hand domain DUF1180 PF06679.12 AIO01775.1 - 2.5 8.5 17.3 0.36 11.2 6.5 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF1180) NUDE_C PF04880.13 AIO01775.1 - 6 7.3 12.2 9.2 6.7 3.1 2.3 1 1 1 2 2 2 0 NUDE protein, C-terminal conserved region baeRF_family11 PF18855.1 AIO01776.1 - 0.0086 16.4 0.3 0.015 15.6 0.3 1.5 1 0 0 1 1 1 1 Bacterial archaeo-eukaryotic release factor family 11 NfI_DNAbd_pre-N PF10524.9 AIO01776.1 - 0.53 10.2 3.3 3.3 7.7 0.5 2.5 2 0 0 2 2 2 0 Nuclear factor I protein pre-N-terminus NYD-SP28_assoc PF14775.6 AIO01777.1 - 0.1 12.7 0.2 0.1 12.7 0.2 5.6 5 1 1 6 6 6 0 Sperm tail C-terminal domain Shugoshin_N PF07558.11 AIO01777.1 - 0.34 10.8 5.6 4.6 7.2 0.5 4.0 3 0 0 3 3 3 0 Shugoshin N-terminal coiled-coil region MutL_C PF08676.11 AIO01778.1 - 2.3e-29 102.1 0.0 4.1e-29 101.2 0.0 1.4 1 0 0 1 1 1 1 MutL C terminal dimerisation domain DNA_mis_repair PF01119.19 AIO01778.1 - 9.1e-12 44.7 0.0 1.6e-11 43.9 0.0 1.4 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.6 AIO01778.1 - 2.3e-06 27.5 0.0 5.8e-06 26.2 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 AIO01778.1 - 0.02 15.4 0.0 0.06 13.9 0.0 1.9 1 1 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Ribosomal_L26 PF16906.5 AIO01779.1 - 1.8e-37 127.7 1.3 2.3e-37 127.3 1.3 1.1 1 0 0 1 1 1 1 Ribosomal proteins L26 eukaryotic, L24P archaeal KOW PF00467.29 AIO01779.1 - 4e-06 26.6 0.5 1e-05 25.3 0.5 1.8 1 1 0 1 1 1 1 KOW motif LRR_8 PF13855.6 AIO01781.1 - 8.1e-13 47.9 17.9 0.0021 17.8 1.2 4.5 2 2 2 4 4 4 4 Leucine rich repeat LRR_4 PF12799.7 AIO01781.1 - 2.5e-11 43.6 13.5 0.0024 18.2 0.2 4.7 2 1 2 5 5 5 4 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 AIO01781.1 - 8.7e-08 31.6 7.9 2.8 8.2 0.2 6.7 6 0 0 6 6 6 2 Leucine Rich repeat LRR_1 PF00560.33 AIO01781.1 - 5.5e-06 26.2 10.1 8.3 7.4 0.0 6.7 6 1 0 6 6 6 1 Leucine Rich Repeat LRR_9 PF14580.6 AIO01781.1 - 0.0017 17.9 3.1 0.41 10.1 0.0 3.0 2 1 1 3 3 3 2 Leucine-rich repeat EzrA PF06160.12 AIO01781.1 - 0.024 12.8 5.1 0.034 12.3 5.1 1.2 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA Spc29 PF17082.5 AIO01781.1 - 0.025 14.4 2.0 0.045 13.6 2.0 1.5 1 0 0 1 1 1 0 Spindle Pole Component 29 DUF4685 PF15737.5 AIO01781.1 - 0.28 11.6 8.9 0.52 10.8 0.1 3.2 2 1 1 3 3 3 0 Domain of unknown function (DUF4685) Takusan PF04822.13 AIO01781.1 - 1.5 8.7 7.1 4.8 7.1 7.1 1.9 1 1 0 1 1 1 0 Takusan DivIVA PF05103.13 AIO01781.1 - 4.1 7.5 11.7 1.5 8.9 2.8 2.2 1 1 1 2 2 2 0 DivIVA protein APG6_N PF17675.1 AIO01781.1 - 7.3 7.1 13.6 15 6.1 13.6 1.5 1 0 0 1 1 1 0 Apg6 coiled-coil region RTC PF01137.21 AIO01782.1 - 8.2e-43 146.2 0.1 9.3e-43 146.0 0.1 1.0 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase RTC_insert PF05189.13 AIO01782.1 - 1.8e-27 95.8 0.1 2.9e-27 95.2 0.1 1.3 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase (RTC), insert domain Pro_isomerase PF00160.21 AIO01783.1 - 8.5e-09 35.9 0.0 1.3e-08 35.2 0.0 1.3 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Pkinase PF00069.25 AIO01784.1 - 1e-57 195.6 0.0 1.2e-57 195.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 AIO01784.1 - 2.5e-18 66.3 0.0 3.4e-18 65.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 AIO01784.1 - 1.8e-05 24.8 0.0 0.0017 18.4 0.0 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kinase-like PF14531.6 AIO01784.1 - 0.011 15.1 0.0 0.019 14.3 0.0 1.3 1 0 0 1 1 1 0 Kinase-like UCH PF00443.29 AIO01785.1 - 5.4e-48 163.7 0.4 9.4e-48 162.9 0.4 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 AIO01785.1 - 6.1e-20 72.1 0.4 1.7e-18 67.3 0.3 2.8 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase USP7_ICP0_bdg PF12436.8 AIO01785.1 - 9.4e-10 38.2 0.1 2.5e-09 36.8 0.0 1.7 2 0 0 2 2 2 1 ICP0-binding domain of Ubiquitin-specific protease 7 USP7_C2 PF14533.6 AIO01785.1 - 3e-09 36.9 0.0 1.4e-08 34.7 0.0 2.1 1 1 0 1 1 1 1 Ubiquitin-specific protease C-terminal Robl_LC7 PF03259.17 AIO01786.1 - 4e-19 68.2 0.0 4.5e-19 68.0 0.0 1.0 1 0 0 1 1 1 1 Roadblock/LC7 domain LAMTOR5 PF16672.5 AIO01786.1 - 1.2e-06 28.3 0.0 1.4e-06 28.1 0.0 1.1 1 0 0 1 1 1 1 Ragulator complex protein LAMTOR5 CRM1_repeat_2 PF18784.1 AIO01786.1 - 0.026 14.2 0.0 0.041 13.5 0.0 1.4 1 0 0 1 1 1 0 CRM1 / Exportin repeat 2 Notch PF00066.17 AIO01787.1 - 0.23 11.9 0.8 0.56 10.7 0.8 1.6 1 0 0 1 1 1 0 LNR domain SP2 PF03014.14 AIO01788.1 - 0.15 10.4 0.0 0.15 10.4 0.0 1.1 1 0 0 1 1 1 0 Structural protein 2 Proteasom_Rpn13 PF04683.13 AIO01789.1 - 7.7e-14 52.0 0.0 1.2e-13 51.4 0.0 1.3 1 0 0 1 1 1 1 Proteasome complex subunit Rpn13 ubiquitin receptor RPN13_C PF16550.5 AIO01789.1 - 5.5e-12 45.9 0.0 9.1e-12 45.2 0.0 1.4 1 1 0 1 1 1 1 UCH-binding domain DUF4205 PF13898.6 AIO01789.1 - 0.15 10.9 0.7 0.55 9.1 0.5 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4205) RskA PF10099.9 AIO01790.1 - 0.014 15.7 0.0 0.021 15.1 0.0 1.5 1 1 0 1 1 1 0 Anti-sigma-K factor rskA Pox_MCEL PF03291.16 AIO01790.1 - 0.081 12.0 0.2 0.13 11.3 0.2 1.3 1 1 0 1 1 1 0 mRNA capping enzyme Alkyl_sulf_C PF14864.6 AIO01790.1 - 0.45 10.8 1.9 0.74 10.1 0.3 1.9 1 1 1 2 2 2 0 Alkyl sulfatase C-terminal TMF_DNA_bd PF12329.8 AIO01790.1 - 0.5 10.4 11.0 3.2 7.8 1.9 2.2 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding DUF4606 PF15379.6 AIO01790.1 - 0.5 10.6 2.5 4 7.7 0.2 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4606) BRE1 PF08647.11 AIO01790.1 - 0.94 9.6 9.1 0.083 13.0 1.7 2.2 1 1 1 2 2 2 0 BRE1 E3 ubiquitin ligase DNA_pol_E_B PF04042.16 AIO01791.1 - 9e-20 70.9 0.0 1.4e-19 70.3 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B DTW PF03942.15 AIO01792.1 - 6.8e-22 78.1 0.0 1.3e-21 77.2 0.0 1.5 1 0 0 1 1 1 1 DTW domain zinc_ribbon_9 PF14369.6 AIO01792.1 - 0.17 12.2 4.6 3.3 8.1 0.5 2.6 1 1 1 2 2 2 0 zinc-ribbon zf-B_box PF00643.24 AIO01792.1 - 0.27 11.4 2.3 0.43 10.8 2.3 1.3 1 0 0 1 1 1 0 B-box zinc finger GAS PF13851.6 AIO01793.1 - 1.5e-57 194.2 28.3 1.5e-57 194.2 28.3 3.3 2 1 0 2 2 2 1 Growth-arrest specific micro-tubule binding TMF_TATA_bd PF12325.8 AIO01793.1 - 0.014 15.6 5.4 0.014 15.6 5.4 4.9 1 1 0 4 4 4 0 TATA element modulatory factor 1 TATA binding DUF948 PF06103.11 AIO01793.1 - 0.036 14.3 16.4 4.8 7.5 5.9 5.0 2 2 0 2 2 2 0 Bacterial protein of unknown function (DUF948) TetR_C_31 PF17940.1 AIO01793.1 - 0.24 11.6 0.0 0.24 11.6 0.0 2.8 4 0 0 4 4 4 0 Tetracyclin repressor-like, C-terminal domain Baculo_PEP_C PF04513.12 AIO01793.1 - 6.6 6.8 16.6 10 6.2 1.8 4.0 1 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus DDE_Tnp_4 PF13359.6 AIO01793.1 - 9.8 5.8 8.0 16 5.1 0.7 2.7 1 1 1 2 2 2 0 DDE superfamily endonuclease Ebp2 PF05890.12 AIO01794.1 - 8.3e-44 150.1 11.4 2e-43 148.9 11.4 1.5 1 1 0 1 1 1 1 Eukaryotic rRNA processing protein EBP2 SPEG_u2 PF16650.5 AIO01794.1 - 0.09 13.0 0.1 0.09 13.0 0.1 2.0 2 0 0 2 2 2 0 Unstructured region on SPEG complex protein EF-1_beta_acid PF10587.9 AIO01794.1 - 0.14 12.6 0.3 0.14 12.6 0.3 4.2 4 1 0 4 4 4 0 Eukaryotic elongation factor 1 beta central acidic region GvpL_GvpF PF06386.11 AIO01794.1 - 3.5 7.5 11.1 0.041 13.8 1.3 2.1 2 0 0 2 2 2 0 Gas vesicle synthesis protein GvpL/GvpF Pox_Ag35 PF03286.14 AIO01794.1 - 8.1 6.2 15.1 1.2 8.9 4.9 2.2 2 0 0 2 2 2 0 Pox virus Ag35 surface protein Lysine_decarbox PF03641.14 AIO01795.1 - 0.022 14.8 0.0 0.053 13.6 0.0 1.7 1 0 0 1 1 1 0 Possible lysine decarboxylase EMP24_GP25L PF01105.24 AIO01797.1 - 6.7e-40 137.0 0.3 9.1e-40 136.5 0.3 1.2 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD MogR_DNAbind PF12181.8 AIO01797.1 - 0.066 13.1 0.7 0.098 12.6 0.7 1.2 1 0 0 1 1 1 0 DNA binding domain of the motility gene repressor (MogR) Pkinase PF00069.25 AIO01798.1 - 3.4e-50 170.9 0.0 4.4e-50 170.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 AIO01798.1 - 1.9e-18 66.7 0.0 3.1e-18 66.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.22 AIO01798.1 - 0.14 11.7 0.1 0.23 11.0 0.1 1.3 1 0 0 1 1 1 0 RIO1 family GAF_2 PF13185.6 AIO01799.1 - 0.069 13.5 0.6 0.75 10.1 0.1 2.9 3 1 1 4 4 4 0 GAF domain TRAF_BIRC3_bd PF16673.5 AIO01799.1 - 0.082 12.7 0.5 0.2 11.5 0.5 1.6 1 0 0 1 1 1 0 TNF receptor-associated factor BIRC3 binding domain BLOC1_2 PF10046.9 AIO01799.1 - 0.38 11.1 2.9 2.5 8.5 1.1 2.3 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Ribosomal_L5e PF17144.4 AIO01800.1 - 2.9e-76 255.0 0.7 5e-76 254.2 0.7 1.4 1 0 0 1 1 1 1 Ribosomal large subunit proteins 60S L5, and 50S L18 Ribosomal_L18_c PF14204.6 AIO01800.1 - 2.5e-26 92.5 9.3 2.5e-26 92.5 9.3 1.8 2 0 0 2 2 2 1 Ribosomal L18 C-terminal region Ribosomal_L18p PF00861.22 AIO01800.1 - 0.0044 17.4 1.0 0.007 16.7 0.0 1.8 2 0 0 2 2 2 1 Ribosomal L18 of archaea, bacteria, mitoch. and chloroplast P53_C PF11619.8 AIO01800.1 - 0.12 12.4 0.0 8.8 6.5 0.0 2.4 2 0 0 2 2 2 0 Transcription factor P53 - C terminal domain Ribosomal_L15e PF00827.17 AIO01801.1 - 2.2e-84 282.0 9.1 2.5e-84 281.8 9.1 1.0 1 0 0 1 1 1 1 Ribosomal L15 Ribosomal_L36e PF01158.18 AIO01802.1 - 6.5e-28 96.8 2.7 7.5e-28 96.6 2.7 1.0 1 0 0 1 1 1 1 Ribosomal protein L36e TMCO5 PF14992.6 AIO01805.1 - 0.0011 18.6 6.1 0.0013 18.4 5.2 1.4 2 0 0 2 2 2 1 TMCO5 family UPF0242 PF06785.11 AIO01805.1 - 0.35 10.9 7.2 0.6 10.2 7.2 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus SseC PF04888.12 AIO01805.1 - 0.35 10.4 3.0 0.26 10.8 0.4 1.9 1 1 0 1 1 1 0 Secretion system effector C (SseC) like family NYD-SP28_assoc PF14775.6 AIO01805.1 - 1.5 9.0 9.0 0.73 10.0 1.5 2.5 1 1 1 2 2 2 0 Sperm tail C-terminal domain PRKG1_interact PF15898.5 AIO01805.1 - 7.4 7.5 13.9 1.3 9.9 1.8 2.8 1 1 1 2 2 2 0 cGMP-dependent protein kinase interacting domain ATP11 PF06644.11 AIO01806.1 - 5.2e-20 72.4 0.5 8.8e-20 71.6 0.5 1.3 1 1 0 1 1 1 1 ATP11 protein UBX PF00789.20 AIO01807.1 - 1.2e-07 31.9 0.0 3.7e-07 30.2 0.0 1.8 2 0 0 2 2 2 1 UBX domain XRN_M PF17846.1 AIO01807.1 - 0.36 9.7 2.7 0.49 9.3 2.7 1.2 1 0 0 1 1 1 0 Xrn1 helical domain Thioredoxin_7 PF13899.6 AIO01807.1 - 0.47 10.7 2.3 1.3 9.3 0.0 2.9 3 0 0 3 3 3 0 Thioredoxin-like Asp-B-Hydro_N PF05279.11 AIO01807.1 - 1.3 9.1 16.0 1.9 8.5 16.0 1.2 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Presenilin PF01080.17 AIO01807.1 - 1.9 7.2 7.4 2.4 6.8 7.4 1.1 1 0 0 1 1 1 0 Presenilin DUF572 PF04502.13 AIO01807.1 - 2.5 7.7 12.2 3.6 7.1 12.2 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) HnRNPA1 PF11627.8 AIO01808.1 - 0.023 14.9 0.6 0.055 13.7 0.6 1.6 1 0 0 1 1 1 0 Nuclear factor hnRNPA1 U1snRNP70_N PF12220.8 AIO01808.1 - 5.9 7.6 8.5 1.1 9.9 0.7 3.0 3 0 0 3 3 3 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal U3_assoc_6 PF08640.11 AIO01809.1 - 1.2e-16 60.5 0.7 3.9e-16 58.9 0.4 2.0 2 0 0 2 2 2 1 U3 small nucleolar RNA-associated protein 6 DUF2694 PF10904.8 AIO01809.1 - 0.02 15.0 2.3 0.21 11.7 0.3 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2694) RmlD_sub_bind PF04321.17 AIO01811.1 - 0.00015 21.0 0.0 0.074 12.1 0.0 2.2 2 0 0 2 2 2 2 RmlD substrate binding domain AAA_lid_7 PF17867.1 AIO01811.1 - 0.17 12.1 0.1 0.6 10.3 0.0 1.9 2 0 0 2 2 2 0 Midasin AAA lid domain EF-hand_6 PF13405.6 AIO01812.1 - 2e-07 30.4 0.0 0.22 11.5 0.1 3.6 3 0 0 3 3 3 2 EF-hand domain EF-hand_1 PF00036.32 AIO01812.1 - 1.3e-05 24.4 0.0 0.22 11.2 0.0 3.5 3 0 0 3 3 3 3 EF hand EF-hand_7 PF13499.6 AIO01812.1 - 1.9e-05 25.0 0.0 0.57 10.7 0.0 3.4 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_8 PF13833.6 AIO01812.1 - 0.15 11.9 0.1 39 4.2 0.1 3.3 3 0 0 3 3 3 0 EF-hand domain pair EF-hand_5 PF13202.6 AIO01812.1 - 0.16 11.5 0.0 0.36 10.4 0.0 1.6 1 0 0 1 1 1 0 EF hand Ank_2 PF12796.7 AIO01813.1 - 2.1e-62 207.7 19.8 3.5e-09 37.1 0.0 14.8 11 3 5 16 16 16 10 Ankyrin repeats (3 copies) Ank_5 PF13857.6 AIO01813.1 - 7.5e-36 121.7 32.2 6.8e-06 26.3 0.3 17.5 13 3 4 17 17 17 9 Ankyrin repeats (many copies) Ank_4 PF13637.6 AIO01813.1 - 4.3e-29 100.5 23.4 0.0014 19.1 0.1 14.9 13 3 3 16 16 16 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 AIO01813.1 - 1.6e-23 80.2 45.4 0.06 13.9 0.0 20.9 24 0 0 24 24 24 9 Ankyrin repeat Ank PF00023.30 AIO01813.1 - 2.5e-20 71.9 53.5 0.033 14.6 0.2 17.8 18 1 0 18 18 18 8 Ankyrin repeat Filamin PF00630.19 AIO01813.1 - 0.00091 20.0 0.0 0.0033 18.2 0.0 1.9 2 0 0 2 2 2 1 Filamin/ABP280 repeat Ribosomal_L32e PF01655.18 AIO01814.1 - 1.8e-39 134.5 0.1 2.2e-39 134.2 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L32 CdiI PF07262.11 AIO01814.1 - 0.12 12.1 0.4 0.2 11.4 0.1 1.5 2 0 0 2 2 2 0 CDI immunity protein SH3_9 PF14604.6 AIO01815.1 - 1.2e-32 111.5 1.1 1.6e-11 43.9 0.0 4.7 5 0 0 5 5 5 3 Variant SH3 domain SH3_1 PF00018.28 AIO01815.1 - 1.3e-27 95.1 0.6 1.5e-10 40.5 0.0 3.4 3 0 0 3 3 3 3 SH3 domain SH3_2 PF07653.17 AIO01815.1 - 5.4e-25 86.8 0.9 5.5e-12 45.2 0.2 3.6 3 0 0 3 3 3 3 Variant SH3 domain TackOD1 PF18551.1 AIO01815.1 - 0.1 12.2 0.6 0.22 11.1 0.6 1.5 1 0 0 1 1 1 0 Thaumarchaeal output domain 1 DUF4205 PF13898.6 AIO01816.1 - 4.9e-20 71.8 0.0 8.5e-20 71.0 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4205) UPF0242 PF06785.11 AIO01816.1 - 1.2 9.2 4.3 2 8.5 4.3 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus E1-E2_ATPase PF00122.20 AIO01817.1 - 4.8e-43 146.8 0.8 4.8e-43 146.8 0.8 2.2 3 0 0 3 3 3 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 AIO01817.1 - 4.3e-28 98.3 4.9 4.3e-28 98.3 4.9 2.3 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 AIO01817.1 - 6.2e-16 59.3 0.0 8.1e-15 55.7 0.0 2.7 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 AIO01817.1 - 1.8e-14 53.6 0.1 4.8e-14 52.2 0.1 1.7 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 AIO01817.1 - 2.3e-09 36.8 0.0 5.2e-09 35.7 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 AIO01817.1 - 2e-06 27.7 2.1 2.3e-05 24.3 0.3 2.4 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Kinesin PF00225.23 AIO01818.1 - 4e-72 243.0 0.1 4.2e-43 147.5 0.0 2.6 3 0 0 3 3 3 2 Kinesin motor domain Microtub_bd PF16796.5 AIO01818.1 - 3.9e-22 78.8 0.0 9.6e-22 77.5 0.0 1.7 1 0 0 1 1 1 1 Microtubule binding Seryl_tRNA_N PF02403.22 AIO01818.1 - 1.7 8.9 5.6 1.9 8.7 4.0 1.9 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain PKI PF02827.16 AIO01821.1 - 0.093 12.9 0.6 0.22 11.7 0.6 1.6 1 0 0 1 1 1 0 cAMP-dependent protein kinase inhibitor Synaptobrevin PF00957.21 AIO01822.1 - 5.5e-14 51.7 0.1 8.9e-14 51.1 0.1 1.3 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.6 AIO01822.1 - 6.5e-07 29.3 0.0 1.1e-06 28.5 0.0 1.4 1 0 0 1 1 1 1 Regulated-SNARE-like domain Herpes_teg_N PF04843.12 AIO01822.1 - 0.12 12.1 0.1 0.47 10.1 0.1 2.0 2 1 1 3 3 3 0 Herpesvirus tegument protein, N-terminal conserved region SDA1 PF05285.12 AIO01823.1 - 0.0037 16.8 16.7 0.0046 16.4 16.7 1.2 1 0 0 1 1 1 1 SDA1 CDC45 PF02724.14 AIO01823.1 - 0.19 10.0 14.1 0.25 9.6 14.1 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF4303 PF14136.6 AIO01823.1 - 1.7 8.3 8.6 10 5.8 6.6 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4303) PTPRCAP PF15713.5 AIO01823.1 - 3.8 7.8 25.4 1.3 9.2 21.5 2.1 2 0 0 2 2 2 0 Protein tyrosine phosphatase receptor type C-associated Nop14 PF04147.12 AIO01823.1 - 6 4.9 26.5 8.3 4.5 26.5 1.1 1 0 0 1 1 1 0 Nop14-like family COPI_C PF06957.11 AIO01823.1 - 8.5 5.0 9.3 13 4.4 9.3 1.2 1 0 0 1 1 1 0 Coatomer (COPI) alpha subunit C-terminus Lipase_3 PF01764.25 AIO01825.1 - 3.5e-05 23.7 0.0 8e-05 22.5 0.0 1.6 1 0 0 1 1 1 1 Lipase (class 3) PGAP1 PF07819.13 AIO01825.1 - 0.0017 18.2 0.1 0.0033 17.2 0.1 1.4 1 0 0 1 1 1 1 PGAP1-like protein Thioesterase PF00975.20 AIO01825.1 - 0.047 13.8 0.0 0.17 12.0 0.0 1.9 1 0 0 1 1 1 0 Thioesterase domain adh_short PF00106.25 AIO01826.1 - 3e-18 66.0 0.2 1.3e-15 57.4 0.1 3.1 2 1 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 AIO01826.1 - 3.4e-08 33.4 0.0 7.4e-07 29.0 0.0 2.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase YjeF_N PF03853.15 AIO01826.1 - 0.1 12.5 0.1 0.3 11.0 0.1 1.7 1 1 0 1 1 1 0 YjeF-related protein N-terminus A_deaminase PF00962.22 AIO01827.1 - 2.7e-59 201.2 0.0 3.4e-59 200.8 0.0 1.1 1 0 0 1 1 1 1 Adenosine/AMP deaminase adh_short PF00106.25 AIO01828.1 - 1.6e-13 50.6 0.2 6.9e-13 48.5 0.1 2.1 3 0 0 3 3 3 1 short chain dehydrogenase adh_short_C2 PF13561.6 AIO01828.1 - 2.5e-08 33.8 0.6 3.4e-07 30.1 0.2 2.6 2 1 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 AIO01828.1 - 0.0026 17.7 0.4 0.02 14.8 0.4 2.2 2 0 0 2 2 2 1 KR domain 3HCDH_N PF02737.18 AIO01828.1 - 0.07 13.0 0.1 0.12 12.2 0.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Ribosomal_L11_N PF03946.14 AIO01830.1 - 1.1e-16 60.5 0.5 1.8e-16 59.7 0.5 1.4 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.19 AIO01830.1 - 1.7e-13 50.8 2.0 1.7e-13 50.8 0.8 1.7 2 0 0 2 2 2 1 Ribosomal protein L11, RNA binding domain RRM_1 PF00076.22 AIO01831.1 - 1.3e-35 121.0 0.0 5e-17 61.5 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_Rrp7 PF17799.1 AIO01831.1 - 4.4e-05 23.3 0.0 0.17 11.7 0.0 2.2 2 0 0 2 2 2 2 Rrp7 RRM-like N-terminal domain RRM_7 PF16367.5 AIO01831.1 - 0.0046 17.0 0.0 0.16 12.1 0.0 2.2 2 0 0 2 2 2 1 RNA recognition motif KMP11 PF03037.16 AIO01832.1 - 1.4e-56 189.2 18.4 1.6e-56 189.1 18.4 1.0 1 0 0 1 1 1 1 Kinetoplastid membrane protein 11 Apolipoprotein PF01442.18 AIO01832.1 - 0.0026 17.7 3.4 0.0079 16.1 3.4 1.7 1 1 0 1 1 1 1 Apolipoprotein A1/A4/E domain Lyase_8_N PF08124.11 AIO01832.1 - 0.014 14.3 1.6 0.014 14.3 1.6 1.1 1 0 0 1 1 1 0 Polysaccharide lyase family 8, N terminal alpha-helical domain DUF3987 PF13148.6 AIO01832.1 - 0.17 10.8 2.8 0.19 10.7 2.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) ABC_membrane_3 PF13748.6 AIO01832.1 - 0.2 10.9 0.1 0.28 10.4 0.1 1.3 1 1 0 1 1 1 0 ABC transporter transmembrane region Adhesin_P1_N PF18652.1 AIO01832.1 - 0.22 11.6 2.8 7.7 6.6 0.2 2.3 1 1 1 2 2 2 0 Adhesin P1 N-terminal domain TipAS PF07739.13 AIO01832.1 - 0.34 11.5 10.0 0.5 10.9 2.9 2.0 1 1 0 2 2 2 0 TipAS antibiotic-recognition domain DUF4890 PF16231.5 AIO01832.1 - 0.35 11.4 9.2 0.39 11.2 9.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4890) HAD_2 PF13419.6 AIO01832.1 - 0.41 10.7 4.4 0.45 10.6 4.4 1.1 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase ZnuA PF01297.17 AIO01832.1 - 0.42 10.0 5.2 0.9 8.9 0.3 2.0 1 1 1 2 2 2 0 Zinc-uptake complex component A periplasmic YtxH PF12732.7 AIO01832.1 - 0.43 11.2 2.6 2.3 8.8 2.6 1.9 1 1 0 1 1 1 0 YtxH-like protein Metal_resist PF13801.6 AIO01832.1 - 0.84 9.8 3.4 2.1 8.5 0.3 2.0 1 1 1 2 2 2 0 Heavy-metal resistance DUF2884 PF11101.8 AIO01832.1 - 2.3 7.6 7.5 4.5 6.7 0.5 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2884) Muted PF14942.6 AIO01832.1 - 5.7 7.3 14.6 4.6 7.6 1.0 2.0 1 1 0 1 1 1 0 Organelle biogenesis, Muted-like protein OmpH PF03938.14 AIO01832.1 - 5.8 7.3 11.6 16 5.9 11.6 1.6 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) KMP11 PF03037.16 AIO01833.1 - 3.6e-56 187.9 18.0 4e-56 187.8 18.0 1.0 1 0 0 1 1 1 1 Kinetoplastid membrane protein 11 Apolipoprotein PF01442.18 AIO01833.1 - 0.0047 16.8 2.8 0.014 15.3 2.8 1.7 1 1 0 1 1 1 1 Apolipoprotein A1/A4/E domain Lyase_8_N PF08124.11 AIO01833.1 - 0.013 14.4 1.5 0.013 14.4 1.5 1.1 1 0 0 1 1 1 0 Polysaccharide lyase family 8, N terminal alpha-helical domain ApoLp-III PF07464.11 AIO01833.1 - 0.027 14.5 2.6 0.041 14.0 2.6 1.4 1 1 0 1 1 1 0 Apolipophorin-III precursor (apoLp-III) DUF3987 PF13148.6 AIO01833.1 - 0.23 10.4 2.6 0.26 10.3 2.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) ABC_membrane_3 PF13748.6 AIO01833.1 - 0.23 10.6 0.1 0.34 10.1 0.1 1.3 1 1 0 1 1 1 0 ABC transporter transmembrane region DUF4890 PF16231.5 AIO01833.1 - 0.27 11.7 9.0 0.3 11.6 9.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4890) YtxH PF12732.7 AIO01833.1 - 0.3 11.7 2.2 1.7 9.2 2.2 1.9 1 1 0 1 1 1 0 YtxH-like protein Adhesin_P1_N PF18652.1 AIO01833.1 - 0.35 10.9 2.9 12 6.0 0.2 2.3 1 1 1 2 2 2 0 Adhesin P1 N-terminal domain ZnuA PF01297.17 AIO01833.1 - 0.36 10.2 4.5 1 8.7 0.3 2.0 1 1 1 2 2 2 0 Zinc-uptake complex component A periplasmic TipAS PF07739.13 AIO01833.1 - 0.36 11.4 9.7 0.51 10.9 2.6 2.0 1 1 0 2 2 2 0 TipAS antibiotic-recognition domain Metal_resist PF13801.6 AIO01833.1 - 0.68 10.1 3.2 2 8.7 0.2 2.0 1 1 1 2 2 2 0 Heavy-metal resistance Imm49 PF15575.6 AIO01833.1 - 0.78 9.5 3.9 0.83 9.4 3.9 1.1 1 0 0 1 1 1 0 Immunity protein 49 DUF2884 PF11101.8 AIO01833.1 - 2.7 7.5 7.5 5.1 6.5 0.5 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2884) OmpH PF03938.14 AIO01833.1 - 4.6 7.6 10.7 12 6.2 10.7 1.6 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) Muted PF14942.6 AIO01833.1 - 5.1 7.4 14.0 4.5 7.6 1.0 2.0 1 1 0 1 1 1 0 Organelle biogenesis, Muted-like protein Vma12 PF11712.8 AIO01833.1 - 9 6.4 7.5 7.7 6.6 3.5 2.4 1 1 1 2 2 2 0 Endoplasmic reticulum-based factor for assembly of V-ATPase KMP11 PF03037.16 AIO01834.1 - 3.6e-56 187.9 18.0 4e-56 187.8 18.0 1.0 1 0 0 1 1 1 1 Kinetoplastid membrane protein 11 Apolipoprotein PF01442.18 AIO01834.1 - 0.0047 16.8 2.8 0.014 15.3 2.8 1.7 1 1 0 1 1 1 1 Apolipoprotein A1/A4/E domain Lyase_8_N PF08124.11 AIO01834.1 - 0.013 14.4 1.5 0.013 14.4 1.5 1.1 1 0 0 1 1 1 0 Polysaccharide lyase family 8, N terminal alpha-helical domain ApoLp-III PF07464.11 AIO01834.1 - 0.027 14.5 2.6 0.041 14.0 2.6 1.4 1 1 0 1 1 1 0 Apolipophorin-III precursor (apoLp-III) DUF3987 PF13148.6 AIO01834.1 - 0.23 10.4 2.6 0.26 10.3 2.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) ABC_membrane_3 PF13748.6 AIO01834.1 - 0.23 10.6 0.1 0.34 10.1 0.1 1.3 1 1 0 1 1 1 0 ABC transporter transmembrane region DUF4890 PF16231.5 AIO01834.1 - 0.27 11.7 9.0 0.3 11.6 9.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4890) YtxH PF12732.7 AIO01834.1 - 0.3 11.7 2.2 1.7 9.2 2.2 1.9 1 1 0 1 1 1 0 YtxH-like protein Adhesin_P1_N PF18652.1 AIO01834.1 - 0.35 10.9 2.9 12 6.0 0.2 2.3 1 1 1 2 2 2 0 Adhesin P1 N-terminal domain ZnuA PF01297.17 AIO01834.1 - 0.36 10.2 4.5 1 8.7 0.3 2.0 1 1 1 2 2 2 0 Zinc-uptake complex component A periplasmic TipAS PF07739.13 AIO01834.1 - 0.36 11.4 9.7 0.51 10.9 2.6 2.0 1 1 0 2 2 2 0 TipAS antibiotic-recognition domain Metal_resist PF13801.6 AIO01834.1 - 0.68 10.1 3.2 2 8.7 0.2 2.0 1 1 1 2 2 2 0 Heavy-metal resistance Imm49 PF15575.6 AIO01834.1 - 0.78 9.5 3.9 0.83 9.4 3.9 1.1 1 0 0 1 1 1 0 Immunity protein 49 DUF2884 PF11101.8 AIO01834.1 - 2.7 7.5 7.5 5.1 6.5 0.5 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2884) OmpH PF03938.14 AIO01834.1 - 4.6 7.6 10.7 12 6.2 10.7 1.6 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) Muted PF14942.6 AIO01834.1 - 5.1 7.4 14.0 4.5 7.6 1.0 2.0 1 1 0 1 1 1 0 Organelle biogenesis, Muted-like protein Vma12 PF11712.8 AIO01834.1 - 9 6.4 7.5 7.7 6.6 3.5 2.4 1 1 1 2 2 2 0 Endoplasmic reticulum-based factor for assembly of V-ATPase ATG_C PF09333.11 AIO01837.1 - 0.05 13.9 0.0 6.5 7.2 0.0 2.9 2 0 0 2 2 2 0 Autophagy-related protein C terminal domain ATP-grasp_4 PF13535.6 AIO01838.1 - 5.6e-10 39.0 0.0 1.1e-08 34.8 0.0 2.2 1 1 0 1 1 1 1 ATP-grasp domain LAL_C2 PF18603.1 AIO01838.1 - 1.2e-05 25.4 0.0 2.6e-05 24.3 0.0 1.6 1 0 0 1 1 1 1 L-amino acid ligase C-terminal domain 2 ATPgrasp_Ter PF15632.6 AIO01838.1 - 0.00026 20.7 0.1 0.17 11.6 0.0 2.3 2 0 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp_3 PF02655.14 AIO01838.1 - 0.0015 18.6 0.0 0.012 15.7 0.0 2.3 1 1 0 1 1 1 1 ATP-grasp domain Dala_Dala_lig_C PF07478.13 AIO01838.1 - 0.058 12.9 0.0 30 4.0 0.0 3.0 3 0 0 3 3 3 0 D-ala D-ala ligase C-terminus CPSase_L_D2 PF02786.17 AIO01838.1 - 0.068 12.7 0.0 8.8 5.8 0.0 2.3 2 0 0 2 2 2 0 Carbamoyl-phosphate synthase L chain, ATP binding domain Helicase_C PF00271.31 AIO01839.1 - 1.4e-08 35.1 0.0 3.4e-08 33.8 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 AIO01839.1 - 3.7e-05 23.6 0.0 9e-05 22.3 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 AIO01839.1 - 0.052 13.8 0.0 0.25 11.6 0.0 2.1 2 0 0 2 2 2 0 AAA domain Pkinase PF00069.25 AIO01844.1 - 1.2e-43 149.4 0.1 2.6e-15 56.5 0.1 3.2 3 0 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.17 AIO01844.1 - 1.3e-25 90.2 0.0 2e-22 79.7 0.1 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 AIO01844.1 - 8.4e-05 22.0 0.0 0.0041 16.5 0.0 2.2 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 AIO01844.1 - 0.13 11.0 0.0 0.25 10.0 0.0 1.4 1 0 0 1 1 1 0 Fungal protein kinase UCR_6-4kD PF08997.10 AIO01844.1 - 0.19 11.7 0.0 0.46 10.5 0.0 1.6 1 0 0 1 1 1 0 Ubiquinol-cytochrome C reductase complex, 6.4kD protein HEAT_EZ PF13513.6 AIO01845.1 - 5.6e-08 33.1 7.5 0.0034 17.8 0.0 5.8 5 1 1 6 6 6 2 HEAT-like repeat HEAT PF02985.22 AIO01845.1 - 1.9e-05 24.5 6.5 3.7 8.1 0.0 7.4 7 0 0 7 7 7 1 HEAT repeat RIX1 PF08167.12 AIO01845.1 - 0.022 14.5 1.5 21 4.8 0.0 3.9 4 1 0 4 4 4 0 rRNA processing/ribosome biogenesis TAF6_C PF07571.13 AIO01845.1 - 0.031 14.6 0.0 38 4.7 0.0 4.0 4 1 0 4 4 4 0 TAF6 C-terminal HEAT repeat domain 2Fe-2S_thioredx PF01257.19 AIO01845.1 - 0.09 12.6 0.1 0.19 11.6 0.1 1.5 1 0 0 1 1 1 0 Thioredoxin-like [2Fe-2S] ferredoxin Arm PF00514.23 AIO01845.1 - 0.13 12.3 3.6 13 6.0 0.3 4.4 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat IBN_N PF03810.19 AIO01845.1 - 0.18 11.7 2.2 0.37 10.7 0.7 2.4 2 0 0 2 2 2 0 Importin-beta N-terminal domain IFRD PF05004.13 AIO01845.1 - 3.9 6.5 5.1 12 4.9 0.1 3.7 3 2 2 5 5 5 0 Interferon-related developmental regulator (IFRD) CAF1 PF04857.20 AIO01846.1 - 1.3e-49 169.1 0.0 1.9e-49 168.6 0.0 1.2 1 0 0 1 1 1 1 CAF1 family ribonuclease NUT PF12881.7 AIO01846.1 - 0.097 11.1 0.1 0.15 10.4 0.1 1.1 1 0 0 1 1 1 0 NUT protein Peptidase_M24 PF00557.24 AIO01847.1 - 2.5e-51 174.3 1.3 3.6e-51 173.8 1.3 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.16 AIO01847.1 - 3.1e-25 88.3 0.0 1.2e-24 86.4 0.0 1.9 2 0 0 2 2 2 1 Aminopeptidase P, N-terminal domain DUF1764 PF08576.10 AIO01848.1 - 1.6e-07 32.2 3.6 2e-07 31.8 1.8 2.1 1 1 2 3 3 3 1 Eukaryotic protein of unknown function (DUF1764) SET PF00856.28 AIO01849.1 - 0.00021 21.7 0.0 0.0062 16.9 0.0 3.0 2 1 0 2 2 2 1 SET domain Spt4 PF06093.13 AIO01851.1 - 4.1e-10 39.6 0.0 5.2e-10 39.3 0.0 1.2 1 0 0 1 1 1 1 Spt4/RpoE2 zinc finger WD40 PF00400.32 AIO01852.1 - 1.7e-05 25.5 0.2 0.6 11.1 0.0 4.7 4 0 0 4 4 4 1 WD domain, G-beta repeat PQQ_2 PF13360.6 AIO01852.1 - 2.5e-05 24.0 2.8 0.00012 21.8 0.9 2.9 2 1 0 3 3 3 1 PQQ-like domain ANAPC4_WD40 PF12894.7 AIO01852.1 - 2.5e-05 24.5 0.1 0.11 12.8 0.0 4.3 4 1 1 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain UCH PF00443.29 AIO01853.1 - 1.8e-35 122.7 0.1 5e-29 101.6 0.0 2.3 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 AIO01853.1 - 6.5e-14 52.2 0.5 1e-12 48.3 0.2 2.7 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase Vps5 PF09325.10 AIO01854.1 - 7e-17 61.8 4.0 1e-16 61.2 4.0 1.1 1 0 0 1 1 1 1 Vps5 C terminal like PX PF00787.24 AIO01854.1 - 6.7e-16 58.3 0.0 1.5e-15 57.2 0.0 1.6 1 0 0 1 1 1 1 PX domain P4Ha_N PF08336.11 AIO01854.1 - 0.029 14.4 0.3 0.63 10.1 0.0 2.4 2 0 0 2 2 2 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region CarbpepA_inh PF02977.15 AIO01855.1 - 1.5 8.7 6.2 5.1 7.0 6.2 1.9 1 0 0 1 1 1 0 Carboxypeptidase A inhibitor FAA_hydrolase PF01557.18 AIO01856.1 - 2.3e-40 138.6 0.0 7.4e-39 133.7 0.0 2.0 1 1 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family DUF3490 PF11995.8 AIO01856.1 - 0.027 14.3 0.0 0.044 13.6 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3490) HECT PF00632.25 AIO01857.1 - 1e-74 251.8 0.0 1.8e-74 251.0 0.0 1.4 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) FYVE PF01363.21 AIO01857.1 - 0.33 11.1 11.5 2 8.6 11.5 2.4 1 0 0 1 1 1 0 FYVE zinc finger CagS PF16707.5 AIO01858.1 - 0.017 15.1 0.1 0.039 14.0 0.1 1.5 1 0 0 1 1 1 0 Cag pathogenicity island protein S of Helicobacter pylori Nop53 PF07767.11 AIO01859.1 - 2.8e-15 56.6 15.5 9.7e-15 54.9 15.5 1.9 1 1 0 1 1 1 1 Nop53 (60S ribosomal biogenesis) HHV6-IE PF03753.13 AIO01859.1 - 0.29 8.6 1.5 0.45 7.9 1.5 1.3 1 0 0 1 1 1 0 Human herpesvirus 6 immediate early protein SR-25 PF10500.9 AIO01859.1 - 4 7.0 18.0 0.25 10.9 11.8 1.9 1 1 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF1053 PF06327.14 AIO01859.1 - 4.3 8.0 7.3 8.5 7.0 0.2 2.6 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1053) FAA_hydro_N_2 PF18288.1 AIO01860.1 - 0.29 11.6 4.2 0.24 11.8 0.8 2.8 2 0 0 2 2 2 0 Fumarylacetoacetase N-terminal domain 2 7TMR-HDED PF07697.11 AIO01860.1 - 0.56 10.3 12.3 0.35 10.9 0.5 2.6 1 1 1 2 2 2 0 7TM-HD extracellular CtIP_N PF10482.9 AIO01860.1 - 1.6 8.8 11.1 0.98 9.5 7.4 2.4 1 1 2 3 3 3 0 Tumour-suppressor protein CtIP N-terminal domain APG6_N PF17675.1 AIO01860.1 - 8.9 6.8 37.3 20 5.7 9.4 2.9 1 1 0 2 2 2 0 Apg6 coiled-coil region Cupin_6 PF12852.7 AIO01861.1 - 0.027 14.2 0.8 0.32 10.7 0.0 2.4 2 0 0 2 2 2 0 Cupin Propep_M14 PF02244.16 AIO01861.1 - 0.13 12.7 0.1 0.43 11.0 0.1 1.9 1 0 0 1 1 1 0 Carboxypeptidase activation peptide Yos1 PF08571.10 AIO01862.1 - 1.1e-25 89.7 0.1 1.7e-25 89.1 0.1 1.3 1 1 0 1 1 1 1 Yos1-like zf-RING_2 PF13639.6 AIO01863.1 - 6.2e-09 36.1 15.0 5.5e-05 23.4 0.5 3.9 3 1 0 3 3 3 2 Ring finger domain zf-RING_5 PF14634.6 AIO01863.1 - 4.6e-07 29.7 15.9 0.00039 20.3 0.7 4.3 3 1 0 3 3 3 2 zinc-RING finger domain zf-RING_UBOX PF13445.6 AIO01863.1 - 7.3e-06 25.9 20.0 0.009 16.0 0.1 5.2 5 0 0 5 5 5 2 RING-type zinc-finger zf-RING_11 PF17123.5 AIO01863.1 - 1.2e-05 25.0 6.6 0.0016 18.1 1.2 4.3 4 1 0 4 4 4 2 RING-like zinc finger Prok-RING_4 PF14447.6 AIO01863.1 - 0.00022 21.0 14.0 1.1 9.2 0.2 5.2 5 0 0 5 5 5 1 Prokaryotic RING finger family 4 IQ PF00612.27 AIO01863.1 - 0.00059 19.4 1.6 0.00059 19.4 1.6 2.3 2 0 0 2 2 2 1 IQ calmodulin-binding motif zf-C3HC4_2 PF13923.6 AIO01863.1 - 0.015 15.1 21.8 0.13 12.1 0.1 5.0 5 0 0 5 5 5 0 Zinc finger, C3HC4 type (RING finger) Zf_RING PF16744.5 AIO01863.1 - 0.022 14.9 0.6 0.022 14.9 0.6 3.4 3 1 1 4 4 3 0 KIAA1045 RING finger zf-C3HC4 PF00097.25 AIO01863.1 - 0.023 14.6 16.0 0.55 10.2 0.1 4.6 4 1 0 4 4 4 0 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 AIO01863.1 - 0.61 10.4 25.3 1.5 9.2 5.3 4.4 3 2 0 3 3 3 0 RING-H2 zinc finger domain Zn_ribbon_17 PF17120.5 AIO01863.1 - 0.62 9.7 10.6 0.69 9.6 0.1 3.3 4 0 0 4 4 4 0 Zinc-ribbon, C4HC2 type LIM PF00412.22 AIO01863.1 - 0.81 10.0 5.4 2.8 8.2 0.2 3.1 3 0 0 3 3 3 0 LIM domain zf-ANAPC11 PF12861.7 AIO01863.1 - 3.2 7.9 14.2 2.6 8.2 1.1 4.1 3 2 0 3 3 3 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-WRNIP1_ubi PF18279.1 AIO01863.1 - 10 7.1 9.2 7.2 7.5 0.3 3.5 3 0 0 3 3 3 0 Werner helicase-interacting protein 1 ubiquitin-binding domain Binary_toxB PF03495.14 AIO01864.1 - 0.11 12.7 0.0 0.46 10.7 0.0 2.0 1 1 0 1 1 1 0 Clostridial binary toxin B/anthrax toxin PA Ca-binding domain SUR7 PF06687.12 AIO01865.1 - 0.21 11.2 9.9 0.016 14.8 4.9 1.7 2 0 0 2 2 2 0 SUR7/PalI family Ndc1_Nup PF09531.10 AIO01865.1 - 1.6 7.3 8.8 2.2 6.9 8.8 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup RRM_1 PF00076.22 AIO01866.1 - 3.1e-26 91.0 0.1 4e-14 52.2 0.0 3.5 2 1 1 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 AIO01866.1 - 6.6e-08 32.6 0.0 0.0097 16.0 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif RRM_Rrp7 PF17799.1 AIO01866.1 - 0.017 15.0 0.0 3.4 7.5 0.0 2.4 2 0 0 2 2 2 0 Rrp7 RRM-like N-terminal domain RRM_occluded PF16842.5 AIO01866.1 - 0.032 14.1 0.0 3.7 7.5 0.0 3.3 3 1 0 3 3 3 0 Occluded RNA-recognition motif FAD_binding_1 PF00667.20 AIO01867.1 - 3.8e-29 101.9 0.0 6.2e-29 101.2 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.25 AIO01867.1 - 3.4e-17 63.0 0.0 3.1e-12 46.9 0.0 2.5 2 0 0 2 2 2 2 Flavodoxin FAD_binding_6 PF00970.24 AIO01867.1 - 0.00053 20.3 0.0 0.0035 17.7 0.0 2.1 2 0 0 2 2 2 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.21 AIO01867.1 - 0.038 14.6 0.1 0.18 12.5 0.1 2.2 1 1 1 2 2 2 0 Oxidoreductase NAD-binding domain FixS PF03597.15 AIO01869.1 - 0.12 12.1 0.1 0.22 11.2 0.1 1.4 1 0 0 1 1 1 0 Cytochrome oxidase maturation protein cbb3-type DHHC PF01529.20 AIO01870.1 - 6.9e-26 90.9 13.1 6.9e-26 90.9 13.1 2.1 2 1 0 2 2 2 1 DHHC palmitoyltransferase Phage_holin_3_6 PF07332.11 AIO01870.1 - 0.012 15.6 1.0 0.012 15.6 1.0 2.2 2 0 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III DUF1772 PF08592.11 AIO01870.1 - 0.62 10.4 8.5 0.16 12.3 0.5 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1772) CD47 PF04549.14 AIO01870.1 - 1.9 8.7 11.9 0.067 13.4 5.3 1.8 2 0 0 2 2 2 0 CD47 transmembrane region Retinal PF15449.6 AIO01871.1 - 1.5 6.5 21.0 1.8 6.3 21.0 1.2 1 0 0 1 1 1 0 Retinal protein NIF PF03031.18 AIO01872.1 - 9.6e-27 93.7 1.3 9.7e-27 93.7 0.2 1.5 2 0 0 2 2 2 1 NLI interacting factor-like phosphatase DUF2868 PF11067.8 AIO01872.1 - 0.08 12.4 3.0 2.4 7.6 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2868) K_channel_TID PF07941.11 AIO01872.1 - 2.1 8.8 12.7 0.41 11.1 4.0 2.4 2 0 0 2 2 2 0 Potassium channel Kv1.4 tandem inactivation domain DUF1180 PF06679.12 AIO01872.1 - 4.5 7.6 14.8 0.18 12.2 1.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1180) zf-HC5HC2H PF13771.6 AIO01873.1 - 1.9e-05 24.8 8.2 1.9e-05 24.8 8.2 2.4 2 0 0 2 2 2 1 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.6 AIO01873.1 - 0.00036 20.6 9.6 0.00036 20.6 9.6 2.5 2 1 0 2 2 2 1 PHD-zinc-finger like domain TruD PF01142.18 AIO01874.1 - 0.0002 20.3 0.0 0.34 9.7 0.0 2.3 2 0 0 2 2 2 2 tRNA pseudouridine synthase D (TruD) BST2 PF16716.5 AIO01876.1 - 0.014 16.0 3.9 0.014 16.0 3.9 2.5 2 0 0 2 2 2 0 Bone marrow stromal antigen 2 RhoGEF67_u1 PF16615.5 AIO01876.1 - 0.094 13.2 0.4 0.094 13.2 0.4 4.8 4 1 1 5 5 5 0 Unstructured region one on RhoGEF 6 and 7 Ank_4 PF13637.6 AIO01877.1 - 3.5e-25 88.1 1.4 2.2e-11 44.1 0.0 3.3 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 AIO01877.1 - 3.8e-20 72.2 0.2 2.7e-13 50.3 0.0 2.3 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 AIO01877.1 - 1.5e-18 66.3 0.7 3.1e-09 36.8 0.0 3.7 4 0 0 4 4 4 3 Ankyrin repeat Ank_3 PF13606.6 AIO01877.1 - 8.3e-18 62.7 0.4 4.1e-05 23.7 0.0 3.7 4 0 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.6 AIO01877.1 - 7.3e-17 61.2 4.7 2.2e-09 37.4 0.1 3.5 2 1 2 4 4 4 3 Ankyrin repeats (many copies) GATase_7 PF13537.6 AIO01877.1 - 0.047 13.6 0.1 0.39 10.6 0.0 2.1 1 1 1 2 2 2 0 Glutamine amidotransferase domain BTB_2 PF02214.22 AIO01878.1 - 3.6e-12 46.5 0.0 1.7e-11 44.3 0.0 2.0 2 0 0 2 2 2 1 BTB/POZ domain DUF3181 PF11378.8 AIO01878.1 - 0.19 12.0 0.0 0.37 11.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3181) TRAPPC9-Trs120 PF08626.11 AIO01879.1 - 4.2e-05 21.2 0.1 0.0011 16.4 0.0 2.6 3 0 0 3 3 3 2 Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit SNARE PF05739.19 AIO01881.1 - 9.9e-12 44.7 0.2 3.2e-11 43.0 0.2 1.9 1 0 0 1 1 1 1 SNARE domain Syntaxin PF00804.25 AIO01881.1 - 1.3e-05 24.9 16.6 2e-05 24.4 16.6 1.3 1 0 0 1 1 1 1 Syntaxin Lipoprotein_6 PF01441.19 AIO01881.1 - 0.039 14.0 2.2 0.12 12.3 0.6 2.2 2 0 0 2 2 2 0 Lipoprotein Syntaxin_2 PF14523.6 AIO01881.1 - 0.063 13.6 8.5 0.097 13.0 2.5 2.6 2 1 0 2 2 2 0 Syntaxin-like protein Acyl-CoA_dh_1 PF00441.24 AIO01883.1 - 3.6e-40 137.6 3.1 5.3e-40 137.1 3.1 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 AIO01883.1 - 3.6e-27 94.4 0.7 9.1e-27 93.1 0.1 2.0 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 AIO01883.1 - 5.5e-26 91.5 0.0 1.6e-25 89.9 0.0 1.8 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 AIO01883.1 - 9.5e-21 74.5 0.1 1.7e-20 73.6 0.1 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain HpaB_N PF11794.8 AIO01883.1 - 0.082 12.6 0.2 0.42 10.2 0.1 2.2 1 1 1 2 2 2 0 4-hydroxyphenylacetate 3-hydroxylase N terminal GalKase_gal_bdg PF10509.9 AIO01884.1 - 1.9e-14 52.9 0.0 6.7e-14 51.2 0.0 2.0 1 0 0 1 1 1 1 Galactokinase galactose-binding signature GHMP_kinases_C PF08544.13 AIO01884.1 - 7.6e-08 32.6 0.1 2.7e-07 30.9 0.0 2.0 2 0 0 2 2 2 1 GHMP kinases C terminal GHMP_kinases_N PF00288.26 AIO01884.1 - 1.6e-06 28.3 0.1 3.2e-06 27.3 0.1 1.6 1 0 0 1 1 1 1 GHMP kinases N terminal domain Speriolin_N PF15058.6 AIO01885.1 - 0.71 9.9 8.0 0.17 11.9 1.9 2.8 3 0 0 3 3 3 0 Speriolin N terminus MMR_HSR1 PF01926.23 AIO01886.1 - 1.8e-06 28.0 0.0 4.1e-06 26.8 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 AIO01886.1 - 0.0029 17.1 0.0 0.033 13.7 0.0 2.4 3 0 0 3 3 3 1 Ferrous iron transport protein B AAA_16 PF13191.6 AIO01886.1 - 0.011 16.2 0.0 0.04 14.3 0.0 2.0 1 0 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 AIO01886.1 - 0.081 13.2 0.1 9 6.6 0.0 2.6 2 0 0 2 2 2 0 AAA domain Gtr1_RagA PF04670.12 AIO01886.1 - 0.1 11.9 0.0 0.17 11.2 0.0 1.3 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region IQ PF00612.27 AIO01887.1 - 1.3e-05 24.6 2.2 3.2e-05 23.3 1.5 2.2 2 0 0 2 2 2 1 IQ calmodulin-binding motif Dpy-30 PF05186.13 AIO01887.1 - 0.019 14.7 0.1 0.04 13.6 0.1 1.6 1 0 0 1 1 1 0 Dpy-30 motif MFS_1 PF07690.16 AIO01888.1 - 5.9e-27 94.5 29.7 1.7e-20 73.3 10.6 2.3 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 AIO01888.1 - 1.6e-06 27.3 12.5 1.6e-06 27.3 12.5 1.9 2 0 0 2 2 2 1 Sugar (and other) transporter DUF5075 PF16825.5 AIO01889.1 - 0.0015 18.3 0.4 0.0024 17.6 0.4 1.3 1 0 0 1 1 1 1 IGP family C-type lectin domain TMEM52 PF14979.6 AIO01889.1 - 0.055 13.4 1.8 0.11 12.5 1.8 1.4 1 0 0 1 1 1 0 Transmembrane 52 DUF4492 PF14899.6 AIO01889.1 - 0.084 12.8 0.1 0.16 12.0 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4492) UPF0370 PF13980.6 AIO01889.1 - 0.45 10.6 5.4 0.87 9.7 5.4 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0370) Abhydrolase_1 PF00561.20 AIO01890.1 - 4.8e-08 33.0 0.1 6.8e-08 32.5 0.1 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 AIO01890.1 - 2.9e-07 30.0 0.1 5.3e-07 29.1 0.1 1.5 1 0 0 1 1 1 1 Serine aminopeptidase, S33 DUF818 PF05677.12 AIO01890.1 - 1.5e-05 24.1 0.0 1.9e-05 23.8 0.0 1.2 1 0 0 1 1 1 1 Chlamydia CHLPS protein (DUF818) Peptidase_S9 PF00326.21 AIO01890.1 - 0.00098 18.7 0.0 0.0013 18.2 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_6 PF12697.7 AIO01890.1 - 0.0047 17.6 0.6 0.012 16.2 0.1 1.9 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.13 AIO01890.1 - 0.024 14.5 0.0 0.039 13.8 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold LIDHydrolase PF10230.9 AIO01890.1 - 0.047 13.2 0.0 0.19 11.2 0.0 1.9 2 0 0 2 2 2 0 Lipid-droplet associated hydrolase DUF676 PF05057.14 AIO01890.1 - 0.066 12.7 0.0 0.23 10.9 0.0 1.8 2 0 0 2 2 2 0 Putative serine esterase (DUF676) MFS_1 PF07690.16 AIO01891.1 - 1.3e-19 70.3 42.4 1.1e-17 64.0 18.9 2.6 2 2 1 3 3 3 3 Major Facilitator Superfamily MFS_1_like PF12832.7 AIO01891.1 - 5.3e-10 38.7 5.1 0.00035 19.6 4.2 3.2 2 1 1 3 3 3 2 MFS_1 like family Sugar_tr PF00083.24 AIO01891.1 - 8.6e-05 21.6 9.3 8.6e-05 21.6 9.3 2.9 3 0 0 3 3 3 1 Sugar (and other) transporter DUF1614 PF07758.11 AIO01891.1 - 0.52 10.3 6.8 0.072 13.1 1.9 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1614) MFS_1 PF07690.16 AIO01892.1 - 7.4e-21 74.4 10.7 8e-21 74.3 10.7 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_1_like PF12832.7 AIO01892.1 - 5e-09 35.5 7.0 0.00091 18.2 0.0 2.1 1 1 1 2 2 2 2 MFS_1 like family Sugar_tr PF00083.24 AIO01892.1 - 4.9e-05 22.4 10.2 6.6e-05 21.9 10.2 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_4 PF06779.14 AIO01892.1 - 0.0013 18.2 6.5 0.0032 16.8 6.5 1.6 1 1 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB MFS_1 PF07690.16 AIO01893.1 - 1.7e-24 86.4 34.5 8.9e-20 70.9 8.4 2.3 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 AIO01893.1 - 1.2e-06 27.7 3.7 1.2e-06 27.7 3.7 2.2 2 0 0 2 2 2 1 Sugar (and other) transporter Cytochrom_B_N_2 PF13631.6 AIO01893.1 - 0.15 12.1 3.4 4.9 7.1 0.3 2.9 3 0 0 3 3 3 0 Cytochrome b(N-terminal)/b6/petB Aminotran_5 PF00266.19 AIO01895.1 - 1.2e-47 162.6 0.2 1.4e-31 109.8 0.1 2.1 2 0 0 2 2 2 2 Aminotransferase class-V Leo1 PF04004.13 AIO01896.1 - 4.6e-11 42.8 0.0 1.3e-10 41.3 0.0 1.8 1 0 0 1 1 1 1 Leo1-like protein Alb1 PF09135.11 AIO01897.1 - 0.013 16.3 25.8 6.7 7.7 25.8 2.3 1 1 0 1 1 1 0 Alb1 PLC-beta_C PF08703.10 AIO01897.1 - 0.013 15.5 16.9 0.08 12.9 10.0 2.1 2 0 0 2 2 2 0 PLC-beta C terminal DIT1_PvcA PF05141.12 AIO01897.1 - 0.033 13.6 9.3 0.039 13.4 9.3 1.0 1 0 0 1 1 1 0 Pyoverdine/dityrosine biosynthesis protein Exonuc_VII_L PF02601.15 AIO01897.1 - 4.8 6.7 11.9 5.3 6.5 11.9 1.0 1 0 0 1 1 1 0 Exonuclease VII, large subunit Pkinase PF00069.25 AIO01898.1 - 7.4e-07 28.8 0.1 0.00025 20.5 0.0 2.8 3 0 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 AIO01898.1 - 2.4e-05 23.8 0.0 0.00012 21.4 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase Tmpp129 PF10272.9 AIO01898.1 - 0.4 9.9 0.0 0.4 9.9 0.0 1.7 2 0 0 2 2 2 0 Putative transmembrane protein precursor Sybindin PF04099.12 AIO01899.1 - 3.3e-17 62.7 0.1 3.8e-17 62.6 0.1 1.0 1 0 0 1 1 1 1 Sybindin-like family Tmpp129 PF10272.9 AIO01899.1 - 0.032 13.6 0.0 0.032 13.5 0.0 1.1 1 0 0 1 1 1 0 Putative transmembrane protein precursor CHU_C PF13585.6 AIO01899.1 - 0.042 13.9 0.1 0.067 13.3 0.1 1.4 1 0 0 1 1 1 0 C-terminal domain of CHU protein family SpoU_methylase PF00588.19 AIO01900.1 - 2.2e-07 31.2 0.0 6.4e-07 29.6 0.0 1.8 1 0 0 1 1 1 1 SpoU rRNA Methylase family NAGidase PF07555.13 AIO01900.1 - 0.072 12.4 0.0 0.12 11.7 0.0 1.2 1 0 0 1 1 1 0 beta-N-acetylglucosaminidase PGA2 PF07543.12 AIO01900.1 - 0.096 12.7 3.0 0.17 11.9 3.0 1.4 1 0 0 1 1 1 0 Protein trafficking PGA2 OrfB_IS605 PF01385.19 AIO01900.1 - 4.6 7.5 5.9 3.3 8.0 2.5 2.5 2 1 0 2 2 2 0 Probable transposase Tctex-1 PF03645.13 AIO01902.1 - 9.9e-28 96.4 0.1 1.2e-27 96.2 0.1 1.0 1 0 0 1 1 1 1 Tctex-1 family DSPc PF00782.20 AIO01902.1 - 0.0037 17.1 0.0 0.0048 16.7 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain DUF4200 PF13863.6 AIO01903.1 - 0.003 18.0 5.6 0.0077 16.6 5.6 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4200) TMF_DNA_bd PF12329.8 AIO01903.1 - 0.038 14.0 0.9 0.082 12.9 0.9 1.5 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding DUF641 PF04859.12 AIO01903.1 - 0.039 14.3 0.8 0.24 11.7 1.0 2.2 2 0 0 2 2 2 0 Plant protein of unknown function (DUF641) Not3 PF04065.15 AIO01903.1 - 0.086 12.3 2.4 0.15 11.5 2.4 1.3 1 0 0 1 1 1 0 Not1 N-terminal domain, CCR4-Not complex component UPF0242 PF06785.11 AIO01903.1 - 0.35 11.0 4.3 0.7 10.0 4.3 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Uso1_p115_C PF04871.13 AIO01903.1 - 0.56 10.6 4.5 1.3 9.4 4.5 1.6 1 0 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region PRKG1_interact PF15898.5 AIO01903.1 - 1.1 10.2 5.1 34 5.4 4.3 2.9 2 0 0 2 2 2 0 cGMP-dependent protein kinase interacting domain DUF2968 PF11180.8 AIO01903.1 - 2.7 7.6 11.2 3.5 7.2 9.8 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2968) TMF_TATA_bd PF12325.8 AIO01903.1 - 7.7 6.8 9.1 3.6 7.8 4.2 2.6 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding UPF0182 PF03699.13 AIO01904.1 - 0.8 7.8 4.1 1.5 6.8 4.1 1.7 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0182) Cupin_8 PF13621.6 AIO01905.1 - 3.9e-45 154.5 0.0 7.1e-45 153.7 0.0 1.3 1 0 0 1 1 1 1 Cupin-like domain LCM PF04072.14 AIO01905.1 - 4.2e-16 59.4 0.0 2.7e-09 37.3 0.0 2.8 2 1 0 2 2 2 2 Leucine carboxyl methyltransferase Kelch_5 PF13854.6 AIO01905.1 - 1.4e-08 34.5 0.2 0.48 10.5 0.0 5.4 5 0 0 5 5 5 2 Kelch motif Cupin_4 PF08007.12 AIO01905.1 - 0.00029 20.4 0.0 0.00085 18.9 0.0 1.5 1 1 0 1 1 1 1 Cupin superfamily protein Kelch_4 PF13418.6 AIO01905.1 - 0.019 15.0 6.7 0.3 11.1 0.0 4.5 5 0 0 5 5 5 0 Galactose oxidase, central domain Kelch_3 PF13415.6 AIO01905.1 - 0.022 15.0 6.0 2.1 8.7 0.0 4.3 5 0 0 5 5 5 0 Galactose oxidase, central domain PPR_2 PF13041.6 AIO01906.1 - 1.3e-21 76.5 10.8 4.5e-07 30.0 0.0 8.9 6 1 4 10 10 10 7 PPR repeat family PPR PF01535.20 AIO01906.1 - 5.4e-21 73.3 31.6 0.014 15.6 0.0 12.3 16 0 0 16 16 16 6 PPR repeat PPR_3 PF13812.6 AIO01906.1 - 2.4e-14 53.2 9.7 0.007 16.4 0.1 7.8 5 1 4 9 9 9 6 Pentatricopeptide repeat domain PPR_1 PF12854.7 AIO01906.1 - 4.3e-10 39.1 0.3 0.41 10.4 0.0 6.4 6 0 0 6 6 6 3 PPR repeat PPR_long PF17177.4 AIO01906.1 - 5.7e-06 25.8 14.9 2.8e-05 23.6 0.6 5.8 3 1 3 6 6 6 2 Pentacotripeptide-repeat region of PRORP RNA_pol_Rpb4 PF03874.16 AIO01906.1 - 0.23 11.8 1.1 75 3.7 0.0 4.4 4 2 0 4 4 4 0 RNA polymerase Rpb4 SPOB_a PF14689.6 AIO01906.1 - 0.6 9.9 3.6 51 3.7 0.1 4.7 5 0 0 5 5 5 0 Sensor_kinase_SpoOB-type, alpha-helical domain TPR_19 PF14559.6 AIO01906.1 - 2 9.0 6.3 22 5.6 0.0 4.7 5 1 0 5 5 5 0 Tetratricopeptide repeat DENN PF02141.21 AIO01907.1 - 1.6e-22 80.3 0.5 3.1e-22 79.4 0.5 1.4 1 0 0 1 1 1 1 DENN (AEX-3) domain TPR_14 PF13428.6 AIO01908.1 - 0.14 13.1 0.8 2.2 9.3 0.1 3.0 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.17 AIO01908.1 - 0.3 11.3 1.8 41 4.6 0.1 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat DnaJ_C PF01556.18 AIO01909.1 - 1.4e-31 109.6 0.0 1.9e-31 109.2 0.0 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 AIO01909.1 - 1.4e-21 76.3 0.9 3e-21 75.3 0.9 1.6 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 AIO01909.1 - 4.5e-15 55.8 19.0 8.9e-15 54.8 19.0 1.5 1 0 0 1 1 1 1 DnaJ central domain Anti-TRAP PF15777.5 AIO01909.1 - 0.00013 21.9 11.0 0.0019 18.1 1.4 2.6 2 0 0 2 2 2 2 Tryptophan RNA-binding attenuator protein inhibitory protein HypA PF01155.19 AIO01909.1 - 0.034 14.2 7.4 0.38 10.8 1.0 2.3 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DNA_pol_A_exo1 PF01612.20 AIO01910.1 - 3.6e-15 56.1 0.0 5.3e-15 55.6 0.0 1.2 1 0 0 1 1 1 1 3'-5' exonuclease zf-C2H2_10 PF16588.5 AIO01910.1 - 0.0018 18.0 10.1 0.0058 16.3 2.1 4.1 5 0 0 5 5 5 3 C2H2 zinc-finger zf-CCHC PF00098.23 AIO01910.1 - 0.0032 17.5 1.4 0.0032 17.5 1.4 5.1 5 1 0 5 5 5 3 Zinc knuckle REV1_C PF16727.5 AIO01910.1 - 0.056 13.8 0.5 0.73 10.3 0.0 2.6 3 1 0 3 3 3 0 DNA repair protein REV1 C-terminal domain Glyoxalase PF00903.25 AIO01912.1 - 1.1e-15 57.9 0.2 1.5e-15 57.6 0.2 1.1 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 AIO01912.1 - 3.3e-09 37.0 0.0 5.1e-09 36.4 0.0 1.4 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.7 AIO01912.1 - 0.016 15.2 0.0 0.032 14.1 0.0 1.6 1 1 0 1 1 1 0 Glyoxalase-like domain Glyoxalase_3 PF13468.6 AIO01912.1 - 0.048 13.8 0.0 5.2 7.1 0.0 2.6 1 1 1 2 2 2 0 Glyoxalase-like domain CppA_N PF14506.6 AIO01912.1 - 0.058 13.5 0.0 0.074 13.1 0.0 1.3 1 1 0 1 1 1 0 CppA N-terminal PAF-AH_p_II PF03403.13 AIO01913.1 - 8.4e-27 93.6 0.0 5.4e-26 91.0 0.0 1.9 1 1 0 1 1 1 1 Platelet-activating factor acetylhydrolase, isoform II Abhydrolase_6 PF12697.7 AIO01913.1 - 6.2e-05 23.7 0.4 0.00023 21.8 0.2 1.8 1 1 1 2 2 2 1 Alpha/beta hydrolase family Chlorophyllase2 PF12740.7 AIO01913.1 - 6.2e-05 22.0 0.0 0.00025 20.1 0.0 1.8 1 1 0 1 1 1 1 Chlorophyllase enzyme Hydrolase_4 PF12146.8 AIO01913.1 - 0.0017 17.7 0.1 1.4 8.1 0.0 2.2 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 AIO01913.1 - 0.0087 15.7 0.2 0.017 14.8 0.0 1.5 2 0 0 2 2 2 1 alpha/beta hydrolase fold Lipase_3 PF01764.25 AIO01913.1 - 0.081 12.8 0.0 0.21 11.5 0.0 1.7 2 0 0 2 2 2 0 Lipase (class 3) Ser_hydrolase PF06821.13 AIO01913.1 - 0.14 12.1 0.1 0.67 9.8 0.0 2.1 2 1 1 3 3 3 0 Serine hydrolase ICMT PF04140.14 AIO01914.1 - 6e-20 71.5 1.1 6e-20 71.5 1.1 2.0 2 1 0 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.13 AIO01914.1 - 2.7e-07 30.9 2.1 2.7e-07 30.9 2.1 3.1 3 2 2 5 5 5 1 Phospholipid methyltransferase DUF1295 PF06966.12 AIO01914.1 - 0.0024 17.4 2.2 0.0024 17.4 2.2 1.9 2 1 1 3 3 3 1 Protein of unknown function (DUF1295) DUF2721 PF11026.8 AIO01914.1 - 0.018 14.9 3.4 0.021 14.7 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2721) OST3_OST6 PF04756.13 AIO01914.1 - 0.077 12.3 0.0 0.15 11.4 0.0 1.4 1 0 0 1 1 1 0 OST3 / OST6 family, transporter family RseC_MucC PF04246.12 AIO01914.1 - 0.98 9.4 3.1 0.58 10.1 0.1 2.0 2 0 0 2 2 2 0 Positive regulator of sigma(E), RseC/MucC NDUFA12 PF05071.16 AIO01915.1 - 6.5e-05 23.7 1.1 6.5e-05 23.7 1.1 2.1 2 1 0 2 2 2 1 NADH ubiquinone oxidoreductase subunit NDUFA12 zf-CCHC_2 PF13696.6 AIO01916.1 - 9.8e-08 31.7 8.2 9.8e-08 31.7 8.2 2.3 2 0 0 2 2 2 1 Zinc knuckle zf-RING_4 PF14570.6 AIO01916.1 - 0.00012 21.7 1.3 0.00012 21.7 1.3 1.8 2 0 0 2 2 2 1 RING/Ubox like zinc-binding domain zf-RING_5 PF14634.6 AIO01916.1 - 0.0011 18.9 4.3 0.0011 18.9 4.3 2.4 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_14 PF17978.1 AIO01916.1 - 0.019 15.4 0.4 0.036 14.5 0.4 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-CCHC PF00098.23 AIO01916.1 - 0.068 13.3 4.5 0.23 11.6 4.5 2.0 1 0 0 1 1 1 0 Zinc knuckle zf-C3HC4 PF00097.25 AIO01916.1 - 0.078 12.9 3.9 0.21 11.5 3.9 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Rtf2 PF04641.12 AIO01916.1 - 0.12 11.7 0.3 0.18 11.1 0.3 1.2 1 0 0 1 1 1 0 Rtf2 RING-finger DUF4428 PF14471.6 AIO01916.1 - 0.18 11.8 3.3 35 4.4 0.1 3.3 2 1 1 3 3 3 0 Domain of unknown function (DUF4428) Prok-RING_4 PF14447.6 AIO01916.1 - 1.1 9.2 13.9 0.11 12.3 7.7 2.5 2 1 0 2 2 2 0 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 AIO01916.1 - 1.8 8.7 9.0 0.2 11.7 3.3 2.4 2 1 1 3 3 3 0 RING-type zinc-finger zf-C3HC4_3 PF13920.6 AIO01916.1 - 1.8 8.5 12.3 0.21 11.4 6.0 2.4 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) FYVE PF01363.21 AIO01916.1 - 2.1 8.6 6.7 0.33 11.1 1.7 2.1 2 0 0 2 2 2 0 FYVE zinc finger DZR PF12773.7 AIO01916.1 - 2.9 8.0 7.1 3.3 7.8 2.1 2.5 2 0 0 2 2 2 0 Double zinc ribbon TF_Zn_Ribbon PF08271.12 AIO01916.1 - 3.8 7.1 8.1 2 8.0 2.6 2.8 2 1 0 2 2 2 0 TFIIB zinc-binding zf-RING_2 PF13639.6 AIO01916.1 - 8.5 6.8 11.5 0.13 12.6 4.1 1.8 2 0 0 2 2 1 0 Ring finger domain ThiF PF00899.21 AIO01917.1 - 3.2e-74 249.3 0.0 4.8e-57 193.1 0.0 2.3 1 1 1 2 2 2 2 ThiF family UBA_e1_thiolCys PF10585.9 AIO01917.1 - 2.2e-56 191.6 0.1 3.1e-56 191.1 0.1 1.2 1 0 0 1 1 1 1 Ubiquitin-activating enzyme active site E1_4HB PF16191.5 AIO01917.1 - 1.5e-11 44.3 0.0 3.1e-11 43.3 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin-activating enzyme E1 four-helix bundle Rhamno_transf PF11316.8 AIO01917.1 - 0.066 12.6 0.0 0.13 11.6 0.0 1.4 1 0 0 1 1 1 0 Putative rhamnosyl transferase 3HCDH_N PF02737.18 AIO01917.1 - 0.13 12.1 0.1 0.38 10.6 0.1 1.8 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Lipocalin_9 PF17186.4 AIO01918.1 - 9.6e-08 32.4 0.4 4.2e-07 30.3 0.0 2.3 3 0 0 3 3 3 1 Lipocalin-like domain FGGY_N PF00370.21 AIO01919.1 - 7.4e-69 232.0 0.0 9.9e-69 231.6 0.0 1.2 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain FGGY_C PF02782.16 AIO01919.1 - 3.8e-58 196.5 0.7 8e-58 195.4 0.7 1.6 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain DnaJ PF00226.31 AIO01920.1 - 9.3e-10 38.5 0.0 2.1e-09 37.3 0.0 1.6 1 0 0 1 1 1 1 DnaJ domain Babuvirus_MP PF07234.11 AIO01920.1 - 0.067 13.4 0.0 0.13 12.4 0.0 1.5 1 0 0 1 1 1 0 Movement and RNA silencing protein DEAD PF00270.29 AIO01921.1 - 1.3e-42 145.5 0.0 2.5e-41 141.4 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 AIO01921.1 - 5.6e-31 107.2 0.1 1.3e-30 106.0 0.1 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 AIO01921.1 - 0.00046 20.2 0.0 0.0011 19.0 0.0 1.6 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 AIO01921.1 - 0.014 14.7 0.1 0.024 13.9 0.1 1.3 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase AAA_22 PF13401.6 AIO01921.1 - 0.05 13.9 0.6 0.51 10.6 0.6 2.4 1 1 0 1 1 1 0 AAA domain EF-hand_7 PF13499.6 AIO01923.1 - 0.21 12.0 0.0 0.51 10.8 0.0 1.6 1 0 0 1 1 1 0 EF-hand domain pair Dynein_light PF01221.18 AIO01924.1 - 1.1e-13 51.3 0.2 1.4e-13 50.9 0.2 1.3 1 1 0 1 1 1 1 Dynein light chain type 1 Ground-like PF04155.18 AIO01924.1 - 0.068 13.8 0.0 0.097 13.3 0.0 1.4 1 0 0 1 1 1 0 Ground-like domain IPK PF03770.16 AIO01925.1 - 9.4e-23 81.1 0.0 1.3e-21 77.3 0.0 2.2 1 1 0 1 1 1 1 Inositol polyphosphate kinase Flavokinase PF01687.17 AIO01927.1 - 1e-25 90.2 0.0 1.2e-25 90.0 0.0 1.1 1 0 0 1 1 1 1 Riboflavin kinase Pkinase PF00069.25 AIO01928.1 - 7.8e-37 127.1 0.0 1.7e-36 126.0 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 AIO01928.1 - 2e-15 56.8 0.0 9.1e-12 44.8 0.1 2.2 1 1 1 2 2 2 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 AIO01928.1 - 4.8e-07 28.9 0.0 2.4e-06 26.6 0.0 1.9 1 1 0 2 2 2 1 Fungal protein kinase APH PF01636.23 AIO01928.1 - 1.7e-05 24.9 0.9 6.9e-05 22.9 0.0 2.3 2 0 0 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.22 AIO01928.1 - 0.0032 17.1 0.0 0.0062 16.1 0.0 1.4 1 0 0 1 1 1 1 RIO1 family His_Phos_1 PF00300.22 AIO01930.1 - 8.5e-13 48.4 0.0 3.5e-10 39.9 0.0 2.3 2 0 0 2 2 2 2 Histidine phosphatase superfamily (branch 1) RRM_1 PF00076.22 AIO01931.1 - 3.3e-06 26.8 0.0 6.2e-06 25.9 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF5585 PF17823.1 AIO01931.1 - 8.8 5.2 33.4 15 4.4 33.4 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5585) EF-hand_13 PF17958.1 AIO01932.1 - 3.9e-17 61.8 0.0 7.3e-17 61.0 0.0 1.5 1 0 0 1 1 1 1 EF-hand domain EF-hand_7 PF13499.6 AIO01932.1 - 3.5e-12 46.6 0.0 1.8e-11 44.3 0.0 2.4 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.6 AIO01932.1 - 0.0049 16.7 0.9 0.018 14.9 0.0 2.5 2 0 0 2 2 2 1 EF-hand domain EF-hand_8 PF13833.6 AIO01932.1 - 0.012 15.5 2.4 2.9 7.8 0.2 2.7 2 0 0 2 2 2 0 EF-hand domain pair EF-hand_1 PF00036.32 AIO01932.1 - 0.027 14.0 4.1 0.11 12.1 0.2 3.3 3 0 0 3 3 3 0 EF hand EF-hand_5 PF13202.6 AIO01932.1 - 0.15 11.6 0.5 0.56 9.8 0.0 2.3 2 0 0 2 2 2 0 EF hand SPOUT_MTase_2 PF14419.6 AIO01933.1 - 0.069 12.5 0.2 4.4 6.6 0.0 2.1 2 0 0 2 2 2 0 AF2226-like SPOUT RNA Methylase fused to THUMP Cys_Met_Meta_PP PF01053.20 AIO01934.1 - 3.3e-128 427.5 0.1 3.7e-128 427.3 0.1 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.17 AIO01934.1 - 2.9e-09 36.7 1.2 1.5e-08 34.4 0.2 2.0 1 1 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.19 AIO01934.1 - 0.00015 20.9 0.1 0.00035 19.7 0.1 1.5 1 1 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 AIO01934.1 - 0.0025 17.2 0.5 0.0062 15.8 0.5 1.6 1 1 0 1 1 1 1 Beta-eliminating lyase DUF3586 PF12131.8 AIO01934.1 - 0.47 10.7 4.5 0.36 11.1 2.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3586) AAA PF00004.29 AIO01936.1 - 1.7e-15 57.6 0.0 3.4e-15 56.6 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rep_fac_C PF08542.11 AIO01936.1 - 2.2e-13 50.4 0.0 6.4e-13 48.9 0.0 1.8 1 0 0 1 1 1 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.6 AIO01936.1 - 3.3e-11 43.2 0.0 1.7e-10 40.9 0.0 2.0 1 1 0 1 1 1 1 DNA polymerase III, delta subunit Rad17 PF03215.15 AIO01936.1 - 1.2e-10 41.6 0.0 2.1e-10 40.8 0.0 1.3 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_30 PF13604.6 AIO01936.1 - 2e-07 30.9 0.1 1.7e-06 27.9 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 AIO01936.1 - 7.6e-06 26.3 0.0 1.8e-05 25.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 AIO01936.1 - 7.7e-06 26.4 0.0 2.9e-05 24.5 0.0 2.0 1 1 0 1 1 1 1 AAA ATPase domain Mg_chelatase PF01078.21 AIO01936.1 - 1.1e-05 25.0 0.0 1.8e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_22 PF13401.6 AIO01936.1 - 1.7e-05 25.2 0.5 0.00021 21.6 0.3 2.6 1 1 1 2 2 2 1 AAA domain AAA_5 PF07728.14 AIO01936.1 - 1.9e-05 24.7 0.0 6e-05 23.1 0.0 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_14 PF13173.6 AIO01936.1 - 3.8e-05 23.7 0.0 6.8e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 AIO01936.1 - 7.3e-05 22.7 0.1 0.0037 17.1 0.0 2.4 1 1 1 2 2 2 1 AAA domain TniB PF05621.11 AIO01936.1 - 0.00014 21.3 0.0 0.0032 16.9 0.0 2.2 2 0 0 2 2 2 1 Bacterial TniB protein AAA_24 PF13479.6 AIO01936.1 - 0.00025 20.9 0.0 0.00045 20.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_23 PF13476.6 AIO01936.1 - 0.00042 20.9 0.0 0.00057 20.4 0.0 1.2 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.12 AIO01936.1 - 0.00081 19.2 0.0 0.0022 17.8 0.0 1.8 2 0 0 2 2 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_assoc_2 PF16193.5 AIO01936.1 - 0.0014 18.9 0.0 0.0053 17.1 0.0 2.0 2 0 0 2 2 1 1 AAA C-terminal domain AAA_29 PF13555.6 AIO01936.1 - 0.0021 17.8 0.0 0.005 16.6 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain ATPase_2 PF01637.18 AIO01936.1 - 0.0021 18.0 0.0 0.004 17.1 0.0 1.4 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea AAA_3 PF07726.11 AIO01936.1 - 0.0025 17.6 0.0 0.022 14.6 0.0 2.4 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) DUF815 PF05673.13 AIO01936.1 - 0.0048 16.1 0.0 0.0077 15.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_7 PF12775.7 AIO01936.1 - 0.0055 16.2 0.0 0.011 15.2 0.0 1.5 1 0 0 1 1 1 1 P-loop containing dynein motor region NB-ARC PF00931.22 AIO01936.1 - 0.023 13.9 0.0 2.6 7.1 0.0 2.2 2 0 0 2 2 2 0 NB-ARC domain Sigma54_activat PF00158.26 AIO01936.1 - 0.026 14.2 0.0 0.14 11.9 0.0 2.0 1 1 0 1 1 1 0 Sigma-54 interaction domain IstB_IS21 PF01695.17 AIO01936.1 - 0.03 14.1 0.0 2.6 7.7 0.0 2.6 3 0 0 3 3 3 0 IstB-like ATP binding protein ResIII PF04851.15 AIO01936.1 - 0.03 14.3 0.0 1 9.4 0.0 2.2 1 1 1 2 2 2 0 Type III restriction enzyme, res subunit MeaB PF03308.16 AIO01936.1 - 0.035 13.1 0.1 0.084 11.8 0.1 1.6 1 1 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_33 PF13671.6 AIO01936.1 - 0.038 14.2 0.1 0.084 13.0 0.1 1.7 2 1 0 2 2 1 0 AAA domain DEAD PF00270.29 AIO01936.1 - 0.04 13.7 0.2 0.33 10.7 0.0 2.0 1 1 1 2 2 2 0 DEAD/DEAH box helicase DSBA PF01323.20 AIO01936.1 - 0.051 13.4 0.1 0.12 12.2 0.0 1.6 2 0 0 2 2 2 0 DSBA-like thioredoxin domain DUF2075 PF09848.9 AIO01936.1 - 0.063 12.5 0.0 0.099 11.9 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) ABC_tran PF00005.27 AIO01936.1 - 0.092 13.3 0.0 0.18 12.3 0.0 1.6 1 1 0 1 1 1 0 ABC transporter FtsK_SpoIIIE PF01580.18 AIO01936.1 - 0.12 11.7 0.0 0.29 10.5 0.0 1.6 2 0 0 2 2 2 0 FtsK/SpoIIIE family Pex19 PF04614.12 AIO01937.1 - 5e-16 59.2 17.2 8.6e-15 55.2 0.0 3.4 2 1 1 3 3 3 3 Pex19 protein family PPR_2 PF13041.6 AIO01937.1 - 0.092 13.0 0.1 0.092 13.0 0.1 2.2 3 0 0 3 3 3 0 PPR repeat family Macoilin PF09726.9 AIO01938.1 - 0.22 10.0 14.5 0.27 9.7 14.5 1.0 1 0 0 1 1 1 0 Macoilin family DUF4551 PF15087.6 AIO01938.1 - 6.6 5.4 12.2 7.6 5.2 12.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Ribosomal_L31e PF01198.19 AIO01939.1 - 5.6e-26 90.6 1.7 2.1e-25 88.7 0.3 2.2 1 1 1 2 2 2 1 Ribosomal protein L31e WD40 PF00400.32 AIO01940.1 - 1.8e-06 28.5 8.5 0.027 15.4 0.4 5.0 5 0 0 5 5 5 3 WD domain, G-beta repeat LRR_9 PF14580.6 AIO01941.1 - 2.2e-11 43.6 2.3 8.2e-10 38.4 0.1 1.8 1 1 1 2 2 2 2 Leucine-rich repeat LRR_8 PF13855.6 AIO01941.1 - 1.5e-07 31.1 2.9 0.00017 21.3 0.1 2.5 2 0 0 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 AIO01941.1 - 4.6e-07 30.1 4.8 0.0019 18.5 2.4 2.7 1 1 2 3 3 3 3 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 AIO01941.1 - 0.00023 21.0 6.3 1.6 9.0 0.1 4.0 4 0 0 4 4 4 2 Leucine Rich repeat LRR_1 PF00560.33 AIO01941.1 - 0.054 14.1 2.3 1.4 9.8 0.0 3.5 2 1 0 2 2 2 0 Leucine Rich Repeat TRAPP PF04051.16 AIO01942.1 - 2.3e-24 85.8 0.0 2.7e-24 85.5 0.0 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component Mito_carr PF00153.27 AIO01943.1 - 2.6e-52 174.7 0.1 2e-18 66.1 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein Complex1_LYR_1 PF13232.6 AIO01943.1 - 0.18 12.4 0.0 0.45 11.2 0.0 1.7 1 0 0 1 1 1 0 Complex1_LYR-like 6PGD PF00393.19 AIO01944.1 - 4.7e-75 252.6 0.0 8.9e-75 251.7 0.0 1.4 2 0 0 2 2 2 1 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.15 AIO01944.1 - 5.5e-46 156.6 0.1 1.4e-45 155.3 0.0 1.6 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase Shikimate_DH PF01488.20 AIO01944.1 - 6.7e-05 23.0 0.1 0.00019 21.5 0.0 1.7 1 1 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase 3HCDH_N PF02737.18 AIO01944.1 - 0.00038 20.4 0.0 0.00066 19.6 0.0 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain F420_oxidored PF03807.17 AIO01944.1 - 0.0058 17.2 0.1 0.014 16.0 0.1 1.7 1 1 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent 2-Hacid_dh_C PF02826.19 AIO01944.1 - 0.0075 15.6 0.1 0.014 14.8 0.1 1.5 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain RuvA_C PF07499.13 AIO01944.1 - 0.019 15.4 0.0 0.043 14.3 0.0 1.6 1 0 0 1 1 1 0 RuvA, C-terminal domain NAD_Gly3P_dh_N PF01210.23 AIO01944.1 - 0.031 14.3 0.0 0.068 13.1 0.0 1.6 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Git3 PF11710.8 AIO01944.1 - 0.09 12.5 0.0 0.19 11.5 0.0 1.4 1 1 0 1 1 1 0 G protein-coupled glucose receptor regulating Gpa2 TP_methylase PF00590.20 AIO01945.1 - 2.4e-20 73.4 0.9 1.1e-19 71.3 0.3 2.3 2 1 0 2 2 2 1 Tetrapyrrole (Corrin/Porphyrin) Methylases DUF2428 PF10350.9 AIO01946.1 - 9.9e-34 116.8 0.3 3.2e-33 115.2 0.1 2.0 2 0 0 2 2 2 1 Putative death-receptor fusion protein (DUF2428) HEAT PF02985.22 AIO01946.1 - 0.061 13.6 10.1 11 6.6 0.5 6.0 4 0 0 4 4 4 0 HEAT repeat PARP_regulatory PF01358.18 AIO01948.1 - 8e-13 48.0 0.0 5.3e-08 32.1 0.0 2.6 2 1 0 2 2 2 2 Poly A polymerase regulatory subunit GCS2 PF04107.13 AIO01949.1 - 0.063 12.6 0.1 3.8 6.8 0.1 2.3 2 0 0 2 2 2 0 Glutamate-cysteine ligase family 2(GCS2) CDC50 PF03381.15 AIO01950.1 - 7e-73 245.6 0.0 8.9e-73 245.2 0.0 1.0 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family DUF3185 PF11381.8 AIO01950.1 - 0.12 12.4 0.4 0.24 11.4 0.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3185) TOH_N PF12549.8 AIO01952.1 - 0.049 13.5 0.4 0.15 12.0 0.4 1.9 1 0 0 1 1 1 0 Tyrosine hydroxylase N terminal Rep_fac-A_3 PF08661.11 AIO01954.1 - 2.2e-07 31.2 0.0 3.9e-07 30.4 0.0 1.4 1 1 0 1 1 1 1 Replication factor A protein 3 Rad4 PF03835.15 AIO01955.1 - 7.7e-20 71.1 0.1 2e-19 69.8 0.1 1.7 1 0 0 1 1 1 1 Rad4 transglutaminase-like domain BHD_3 PF10405.9 AIO01955.1 - 1e-14 54.7 0.0 3e-14 53.2 0.0 1.8 2 0 0 2 2 2 1 Rad4 beta-hairpin domain 3 BHD_1 PF10403.9 AIO01955.1 - 1.3e-08 34.5 0.0 3e-08 33.3 0.0 1.7 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 1 BHD_2 PF10404.9 AIO01955.1 - 0.0034 18.3 1.4 1.1 10.3 0.4 3.9 2 1 0 2 2 2 1 Rad4 beta-hairpin domain 2 peroxidase PF00141.23 AIO01956.1 - 8.6e-09 35.4 0.0 1.1e-08 35.1 0.0 1.2 1 0 0 1 1 1 1 Peroxidase Acyl_transf_1 PF00698.21 AIO01957.1 - 1.1e-22 81.0 0.0 3.4e-22 79.4 0.0 1.8 2 0 0 2 2 2 1 Acyl transferase domain MFS_1_like PF12832.7 AIO01958.1 - 3.7e-16 59.0 13.5 9.9e-16 57.6 13.5 1.6 1 1 0 1 1 1 1 MFS_1 like family Syntaxin PF00804.25 AIO01959.1 - 3.1e-09 36.8 13.6 3.1e-09 36.8 13.6 1.7 2 0 0 2 2 2 1 Syntaxin SNARE PF05739.19 AIO01959.1 - 3e-05 23.9 0.3 6.9e-05 22.8 0.3 1.6 1 0 0 1 1 1 1 SNARE domain Syntaxin_2 PF14523.6 AIO01959.1 - 0.022 15.1 9.1 0.046 14.1 2.8 2.3 2 0 0 2 2 2 0 Syntaxin-like protein ANAPC4 PF12896.7 AIO01959.1 - 0.28 10.6 5.7 0.42 10.1 2.2 2.6 2 1 1 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 4 MCPsignal PF00015.21 AIO01959.1 - 0.39 10.5 6.1 0.18 11.6 0.3 2.3 1 1 1 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain DUF1664 PF07889.12 AIO01959.1 - 2.1 8.4 7.8 0.71 9.9 0.3 2.7 1 1 1 3 3 3 0 Protein of unknown function (DUF1664) DUF3328 PF11807.8 AIO01960.1 - 1.5 8.6 3.6 12 5.6 0.0 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF3328) ThylakoidFormat PF11264.8 AIO01961.1 - 0.012 15.3 1.5 0.032 13.9 1.5 1.7 1 0 0 1 1 1 0 Thylakoid formation protein FYVE PF01363.21 AIO01962.1 - 1.5e-18 66.6 7.0 2.4e-18 66.0 7.0 1.3 1 0 0 1 1 1 1 FYVE zinc finger OrfB_Zn_ribbon PF07282.11 AIO01962.1 - 2.4 8.1 6.4 6.1 6.8 6.4 1.6 1 0 0 1 1 1 0 Putative transposase DNA-binding domain SMC_N PF02463.19 AIO01963.1 - 3.3e-57 193.5 0.0 1.1e-55 188.5 0.0 2.1 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 AIO01963.1 - 3.1e-23 82.3 0.0 3.1e-23 82.3 0.0 2.7 3 0 0 3 3 3 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.6 AIO01963.1 - 7.6e-15 55.5 0.0 9e-07 29.0 0.0 2.4 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 AIO01963.1 - 2.6e-10 41.1 41.3 2.4e-07 31.4 22.8 4.8 2 1 0 2 2 2 1 AAA domain AAA_15 PF13175.6 AIO01963.1 - 5.9e-09 36.1 0.0 5.9e-09 36.1 0.0 2.6 3 1 1 4 4 4 1 AAA ATPase domain AAA_29 PF13555.6 AIO01963.1 - 1.2e-06 28.1 0.0 2.6e-06 27.1 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 AIO01963.1 - 0.033 14.1 0.4 0.34 10.8 0.0 3.0 2 0 0 2 2 2 0 RsgA GTPase ABC_tran PF00005.27 AIO01963.1 - 0.083 13.4 0.0 0.083 13.4 0.0 5.3 4 2 1 5 5 5 0 ABC transporter AAA_22 PF13401.6 AIO01963.1 - 0.15 12.3 5.6 11 6.2 0.0 4.2 3 2 0 3 3 3 0 AAA domain FlaC_arch PF05377.11 AIO01963.1 - 0.33 11.4 11.1 57 4.2 0.4 6.1 5 0 0 5 5 5 0 Flagella accessory protein C (FlaC) NIF PF03031.18 AIO01964.1 - 8.8e-30 103.5 0.0 2.6e-15 56.5 0.0 2.3 2 0 0 2 2 2 2 NLI interacting factor-like phosphatase KH_1 PF00013.29 AIO01966.1 - 0.00049 19.9 0.4 0.0012 18.6 0.4 1.7 1 0 0 1 1 1 1 KH domain DUF2497 PF10691.9 AIO01967.1 - 0.017 15.5 0.5 0.017 15.5 0.5 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF2497) Baculo_PEP_C PF04513.12 AIO01967.1 - 0.033 14.2 3.7 0.81 9.7 0.7 2.9 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Fib_alpha PF08702.10 AIO01967.1 - 0.038 14.2 7.2 1.2 9.3 0.5 2.6 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family DUF1043 PF06295.12 AIO01967.1 - 0.062 13.3 7.0 0.12 12.4 0.8 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1043) zf-C4H2 PF10146.9 AIO01967.1 - 0.5 10.6 10.3 0.16 12.3 0.4 2.6 1 1 1 2 2 2 0 Zinc finger-containing protein BLOC1_2 PF10046.9 AIO01967.1 - 1 9.7 4.1 13 6.1 0.0 3.3 4 0 0 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF1664 PF07889.12 AIO01967.1 - 2.1 8.4 12.0 2.8 8.0 1.4 3.7 2 1 0 3 3 3 0 Protein of unknown function (DUF1664) BshC PF10079.9 AIO01967.1 - 2.3 6.9 8.6 0.43 9.3 4.4 1.7 1 1 1 2 2 2 0 Bacillithiol biosynthesis BshC Exonuc_VII_L PF02601.15 AIO01967.1 - 5.9 6.4 17.7 24 4.4 17.6 2.0 1 1 0 1 1 1 0 Exonuclease VII, large subunit Allexi_40kDa PF05549.11 AIO01967.1 - 7.4 6.0 6.5 2.8 7.4 1.8 2.3 1 1 1 2 2 2 0 Allexivirus 40kDa protein CRAL_TRIO PF00650.20 AIO01968.1 - 6.7e-26 90.9 0.1 1e-25 90.3 0.1 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 AIO01968.1 - 7.8e-06 26.0 0.5 1.7e-05 24.9 0.5 1.6 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain FUSC_2 PF13515.6 AIO01969.1 - 4.6e-08 33.2 6.0 4.6e-08 33.2 6.0 2.5 2 1 0 2 2 2 1 Fusaric acid resistance protein-like FUSC PF04632.12 AIO01969.1 - 0.049 12.2 2.2 0.045 12.3 0.6 1.7 2 0 0 2 2 2 0 Fusaric acid resistance protein family ALMT PF11744.8 AIO01969.1 - 4 6.2 5.6 12 4.6 0.0 2.8 3 0 0 3 3 3 0 Aluminium activated malate transporter XPG_I_2 PF12813.7 AIO01970.1 - 2.4e-36 125.5 0.1 3.8e-36 124.8 0.1 1.3 1 0 0 1 1 1 1 XPG domain containing XPG_I PF00867.18 AIO01970.1 - 1.1e-20 73.8 0.1 2.7e-20 72.5 0.1 1.7 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.17 AIO01970.1 - 4.7e-20 71.9 0.0 1e-19 70.9 0.0 1.5 1 0 0 1 1 1 1 XPG N-terminal domain DUF4347 PF14252.6 AIO01970.1 - 1.1 9.0 3.8 4.4 7.1 0.5 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4347) Methyltransf_23 PF13489.6 AIO01971.1 - 5.9e-26 91.3 0.0 8.2e-26 90.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 AIO01971.1 - 0.00041 21.0 0.0 0.0037 18.0 0.0 2.6 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 AIO01971.1 - 0.0022 18.6 0.0 0.78 10.4 0.0 3.0 4 0 0 4 4 4 1 Methyltransferase domain Methyltransf_25 PF13649.6 AIO01971.1 - 0.019 15.7 0.0 0.17 12.6 0.0 2.4 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_31 PF13847.6 AIO01971.1 - 0.19 11.5 0.0 0.93 9.3 0.0 2.1 3 0 0 3 3 3 0 Methyltransferase domain Pro_isomerase PF00160.21 AIO01972.1 - 3.2e-29 102.2 0.0 7.3e-29 101.1 0.0 1.6 2 0 0 2 2 2 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD NifU_N PF01592.16 AIO01973.1 - 9.6e-50 168.0 0.0 1.2e-49 167.7 0.0 1.1 1 0 0 1 1 1 1 NifU-like N terminal domain MatE PF01554.18 AIO01974.1 - 9.4e-33 113.1 28.9 5.2e-16 58.7 11.2 3.3 3 0 0 3 3 3 3 MatE Rho_RNA_bind PF07497.12 AIO01976.1 - 0.028 14.3 0.0 0.048 13.5 0.0 1.3 1 0 0 1 1 1 0 Rho termination factor, RNA-binding domain NDUF_B7 PF05676.13 AIO01977.1 - 5.2e-09 35.7 0.5 8.8e-09 35.0 0.5 1.3 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) Ribul_P_3_epim PF00834.19 AIO01978.1 - 3.9e-50 170.0 0.0 4.6e-50 169.8 0.0 1.0 1 0 0 1 1 1 1 Ribulose-phosphate 3 epimerase family PEX11 PF05648.14 AIO01979.1 - 9.3e-09 35.1 0.0 1.2e-08 34.8 0.0 1.1 1 0 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) PEX11 PF05648.14 AIO01980.1 - 1.7e-14 53.9 0.0 3.4e-14 52.8 0.0 1.5 1 1 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) Mg_chelatase PF01078.21 AIO01983.1 - 1.4 8.2 3.4 7.7 5.8 0.2 2.9 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI Cullin PF00888.22 AIO01985.1 - 1.3e-15 57.1 0.0 2e-15 56.5 0.0 1.2 1 0 0 1 1 1 1 Cullin family Antibiotic_NAT PF02522.14 AIO01985.1 - 0.013 15.3 0.0 0.039 13.8 0.0 1.8 2 0 0 2 2 2 0 Aminoglycoside 3-N-acetyltransferase Ribosomal_L27A PF00828.19 AIO01986.1 - 5.4e-21 75.6 0.3 6.9e-21 75.3 0.3 1.1 1 0 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A Ribosomal_L27A PF00828.19 AIO01988.1 - 5.4e-21 75.6 0.3 6.9e-21 75.3 0.3 1.1 1 0 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A Ribosomal_L14 PF00238.19 AIO01989.1 - 4.8e-37 126.8 0.0 5.7e-37 126.5 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e Ribosomal_L14 PF00238.19 AIO01990.1 - 4.8e-37 126.8 0.0 5.7e-37 126.5 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e Cep57_CLD_2 PF14197.6 AIO01992.1 - 0.0067 16.5 2.8 0.0067 16.5 2.8 3.4 3 0 0 3 3 3 1 Centrosome localisation domain of PPC89 GIT_CC PF16559.5 AIO01992.1 - 0.06 13.2 1.4 0.61 10.0 0.1 2.9 2 0 0 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor CLZ PF16526.5 AIO01992.1 - 0.21 12.0 9.1 2.5 8.5 0.4 3.9 4 0 0 4 4 4 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Trimer_CC PF08954.11 AIO01992.1 - 0.38 10.3 6.6 1.5 8.4 0.4 3.4 3 1 0 3 3 3 0 Trimerisation motif TSC22 PF01166.18 AIO01992.1 - 1.3 9.4 4.8 6.3 7.2 0.2 3.8 4 0 0 4 4 4 0 TSC-22/dip/bun family Fez1 PF06818.15 AIO01992.1 - 1.4 9.3 12.2 1.4 9.4 3.2 2.6 1 1 1 2 2 2 0 Fez1 CENP-F_leu_zip PF10473.9 AIO01992.1 - 4.1 7.4 13.3 2.5 8.1 1.9 2.9 2 1 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Rab_bind PF16704.5 AIO01992.1 - 6.5 6.9 8.5 1.7 8.7 0.4 3.0 3 0 0 3 3 3 0 Rab binding domain bZIP_2 PF07716.15 AIO01992.1 - 9.8 6.3 15.3 13 5.9 1.9 4.1 4 0 0 4 4 4 0 Basic region leucine zipper SET PF00856.28 AIO01993.1 - 2.9e-06 27.8 0.0 4.4e-06 27.2 0.0 1.2 1 0 0 1 1 1 1 SET domain Proteasome PF00227.26 AIO01994.1 - 2.7e-48 164.0 0.6 3.3e-48 163.7 0.6 1.1 1 0 0 1 1 1 1 Proteasome subunit Pr_beta_C PF12465.8 AIO01994.1 - 0.0026 17.1 0.2 0.0026 17.1 0.2 2.3 2 0 0 2 2 2 1 Proteasome beta subunits C terminal sCache_2 PF17200.4 AIO01994.1 - 0.036 13.9 0.1 0.062 13.2 0.1 1.3 1 0 0 1 1 1 0 Single Cache domain 2 Cobalamin_bind PF01122.19 AIO01994.1 - 0.085 11.7 0.3 0.3 10.0 0.0 1.7 2 0 0 2 2 2 0 Eukaryotic cobalamin-binding protein Ribosomal_S17 PF00366.20 AIO01995.1 - 9.4e-19 67.3 0.6 1.8e-18 66.4 0.6 1.5 1 0 0 1 1 1 1 Ribosomal protein S17 Cpn60_TCP1 PF00118.24 AIO01996.1 - 2.7e-155 517.7 2.1 3.5e-155 517.4 2.1 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family NDK PF00334.19 AIO01997.1 - 7.5e-31 106.9 0.0 5e-28 97.8 0.0 2.3 2 0 0 2 2 2 2 Nucleoside diphosphate kinase DUF1126 PF06565.12 AIO01997.1 - 4.6e-06 26.4 0.0 1.5e-05 24.7 0.1 1.9 2 0 0 2 2 2 1 DUF1126 PH-like domain DUF371 PF04027.13 AIO01997.1 - 0.13 12.3 0.4 2.5 8.1 0.1 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF371) WD40 PF00400.32 AIO01998.1 - 5.8e-28 96.6 15.3 2.8e-08 34.3 0.0 7.4 7 0 0 7 7 7 5 WD domain, G-beta repeat Sof1 PF04158.14 AIO01998.1 - 1.8e-09 37.7 7.8 3.2e-09 36.9 7.8 1.4 1 0 0 1 1 1 1 Sof1-like domain ANAPC4_WD40 PF12894.7 AIO01998.1 - 0.00016 21.9 0.4 0.12 12.7 0.0 4.3 3 1 3 6 6 6 1 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 AIO01998.1 - 0.00035 19.6 0.3 1.5 7.7 0.0 3.4 3 1 1 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 AIO01998.1 - 0.00078 19.4 0.1 0.002 18.0 0.1 1.8 2 0 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 AIO01998.1 - 0.0074 15.6 0.0 0.88 8.8 0.0 3.0 3 0 0 3 3 3 1 WD40-like domain Nup160 PF11715.8 AIO01998.1 - 0.39 9.3 8.2 17 3.9 0.1 4.0 3 2 1 4 4 4 0 Nucleoporin Nup120/160 EF-hand_7 PF13499.6 AIO01999.1 - 1.4e-12 47.9 1.8 3.9e-06 27.2 0.7 2.5 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 AIO01999.1 - 1.2e-10 40.2 1.8 4.5e-08 32.1 0.1 4.0 3 1 1 4 4 4 1 EF hand EF-hand_6 PF13405.6 AIO01999.1 - 2.1e-09 36.5 0.0 3.1e-06 26.7 0.0 3.5 3 1 0 3 3 3 1 EF-hand domain EF-hand_8 PF13833.6 AIO01999.1 - 9.1e-09 35.0 1.5 8.1e-06 25.6 0.3 3.2 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.6 AIO01999.1 - 0.00013 21.3 3.1 0.00013 21.3 0.0 2.5 3 0 0 3 3 3 1 EF hand EF-hand_9 PF14658.6 AIO01999.1 - 0.0031 17.8 0.1 0.86 10.0 0.0 2.2 2 0 0 2 2 2 1 EF-hand domain EF-hand_14 PF17959.1 AIO01999.1 - 0.0049 17.2 0.0 2.5 8.5 0.0 2.2 1 1 1 2 2 2 2 EF-hand domain EF-hand_11 PF08976.11 AIO01999.1 - 0.029 15.2 0.1 0.039 14.8 0.1 1.2 1 0 0 1 1 1 0 EF-hand domain DUF1398 PF07166.11 AIO01999.1 - 0.05 13.7 0.1 0.13 12.4 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1398) UPF0154 PF03672.13 AIO01999.1 - 0.064 13.3 0.0 1.1 9.3 0.0 2.1 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0154) Baculo_p48 PF04878.13 AIO01999.1 - 0.072 12.0 0.1 0.091 11.7 0.1 1.1 1 0 0 1 1 1 0 Baculovirus P48 protein PhetRS_B1 PF18262.1 AIO01999.1 - 0.08 13.2 0.1 0.55 10.5 0.0 2.1 2 0 0 2 2 2 0 Phe-tRNA synthetase beta subunit B1 domain SHIPPO-rpt PF07004.12 AIO02002.1 - 6.5e-19 67.9 42.0 0.075 14.0 0.0 10.0 10 0 0 10 10 10 8 Sperm-tail PG-rich repeat UNC-50 PF05216.13 AIO02003.1 - 3.4e-47 160.9 10.2 4.1e-47 160.6 10.2 1.0 1 0 0 1 1 1 1 UNC-50 family EMC3_TMCO1 PF01956.16 AIO02003.1 - 0.54 10.0 6.9 2.1 8.1 6.9 1.9 1 1 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like INCENP_N PF12178.8 AIO02004.1 - 0.00052 20.0 0.2 0.0011 19.0 0.2 1.5 1 0 0 1 1 1 1 Chromosome passenger complex (CPC) protein INCENP N terminal PROCN PF08083.11 AIO02005.1 - 6.6e-190 631.1 3.6 1.4e-189 630.0 3.6 1.5 1 0 0 1 1 1 1 PROCN (NUC071) domain PRP8_domainIV PF12134.8 AIO02005.1 - 1.9e-91 305.8 0.0 3.1e-91 305.1 0.0 1.3 1 0 0 1 1 1 1 PRP8 domain IV core U6-snRNA_bdg PF10596.9 AIO02005.1 - 8.1e-69 230.6 0.1 1.7e-68 229.5 0.1 1.6 1 0 0 1 1 1 1 U6-snRNA interacting domain of PrP8 U5_2-snRNA_bdg PF10597.9 AIO02005.1 - 2.5e-59 199.1 0.1 7.3e-59 197.7 0.1 1.8 1 0 0 1 1 1 1 U5-snRNA binding site 2 of PrP8 PRO8NT PF08082.11 AIO02005.1 - 4.1e-58 195.6 0.0 1.1e-57 194.3 0.0 1.8 1 0 0 1 1 1 1 PRO8NT (NUC069), PrP8 N-terminal domain RRM_4 PF10598.9 AIO02005.1 - 1.5e-36 124.6 0.1 4.3e-36 123.1 0.1 1.9 1 0 0 1 1 1 1 RNA recognition motif of the spliceosomal PrP8 PROCT PF08084.11 AIO02005.1 - 3.2e-30 104.6 0.0 1.2e-29 102.7 0.0 2.0 2 0 0 2 2 2 1 PROCT (NUC072) domain DUF5480 PF17576.2 AIO02005.1 - 0.016 15.2 0.2 0.037 14.0 0.2 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5480) zf-MIZ PF02891.20 AIO02006.1 - 2.9e-19 68.5 1.2 5.5e-19 67.6 1.2 1.5 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger zf-Nse PF11789.8 AIO02006.1 - 0.00031 20.5 0.1 0.00064 19.5 0.1 1.4 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit Mito_carr PF00153.27 AIO02008.1 - 3.5e-40 135.8 0.7 3.8e-19 68.4 0.0 2.1 2 0 0 2 2 2 2 Mitochondrial carrier protein HECT PF00632.25 AIO02009.1 - 1.4e-47 162.7 0.0 3.4e-47 161.4 0.0 1.6 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Pkinase PF00069.25 AIO02009.1 - 8.5e-46 156.5 0.0 1.7e-45 155.5 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 AIO02009.1 - 8.8e-31 107.1 0.0 1.9e-30 106.0 0.0 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase TPR_1 PF00515.28 AIO02009.1 - 3.2e-13 48.9 1.7 5.8e-06 25.9 0.0 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 AIO02009.1 - 3.9e-13 48.4 4.0 3.4e-05 23.6 0.1 4.2 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_8 PF13181.6 AIO02009.1 - 8.7e-11 41.2 2.4 0.0049 17.0 0.0 4.3 4 0 0 4 4 3 3 Tetratricopeptide repeat TPR_11 PF13414.6 AIO02009.1 - 4e-10 39.2 0.5 3.8e-06 26.5 0.2 3.3 2 1 1 3 3 3 2 TPR repeat TPR_19 PF14559.6 AIO02009.1 - 2.6e-05 24.6 0.8 0.31 11.6 0.0 3.7 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 AIO02009.1 - 6.3e-05 23.5 5.1 0.2 12.6 0.2 3.8 3 0 0 3 3 2 2 Tetratricopeptide repeat Kinase-like PF14531.6 AIO02009.1 - 0.00018 20.9 0.2 0.00057 19.3 0.0 1.9 2 0 0 2 2 2 1 Kinase-like TPR_16 PF13432.6 AIO02009.1 - 0.00022 21.8 0.2 0.00022 21.8 0.2 3.1 2 1 1 3 3 2 1 Tetratricopeptide repeat TPR_7 PF13176.6 AIO02009.1 - 0.00023 20.9 0.8 0.015 15.3 0.1 3.1 2 0 0 2 2 2 1 Tetratricopeptide repeat Kdo PF06293.14 AIO02009.1 - 0.0042 16.5 0.0 0.012 15.0 0.0 1.7 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 AIO02009.1 - 0.0043 17.0 0.0 0.0043 17.0 0.0 3.1 3 0 0 3 3 3 1 Phosphotransferase enzyme family RIO1 PF01163.22 AIO02009.1 - 0.0078 15.8 0.0 0.03 13.9 0.0 2.0 1 0 0 1 1 1 1 RIO1 family TPR_17 PF13431.6 AIO02009.1 - 0.013 15.8 0.1 2.1 8.9 0.0 3.1 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.6 AIO02009.1 - 0.029 15.0 0.2 3.3 8.6 0.0 3.3 2 0 0 2 2 2 0 Tetratricopeptide repeat tRNA-synt_2c PF01411.19 AIO02009.1 - 0.032 12.8 2.3 0.069 11.7 2.3 1.5 1 0 0 1 1 1 0 tRNA synthetases class II (A) TPR_12 PF13424.6 AIO02009.1 - 0.074 13.4 4.1 0.44 10.9 0.1 3.3 2 1 1 3 3 2 0 Tetratricopeptide repeat TPR_9 PF13371.6 AIO02009.1 - 0.77 10.0 8.0 2.6 8.3 0.1 3.7 3 1 1 4 4 3 0 Tetratricopeptide repeat EMP24_GP25L PF01105.24 AIO02009.1 - 4 7.4 8.1 0.2 11.6 0.9 2.3 2 1 0 2 2 2 0 emp24/gp25L/p24 family/GOLD MIT PF04212.18 AIO02009.1 - 5.5 7.1 6.7 0.92 9.6 0.3 3.1 4 0 0 4 4 2 0 MIT (microtubule interacting and transport) domain Pkinase PF00069.25 AIO02010.1 - 4.7e-69 232.7 0.0 5.6e-69 232.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 AIO02010.1 - 1.2e-33 116.5 0.0 1.5e-33 116.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 AIO02010.1 - 1.9e-05 24.1 0.0 2.7e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_C PF00433.24 AIO02010.1 - 0.004 17.8 0.2 0.01 16.6 0.2 1.7 1 0 0 1 1 1 1 Protein kinase C terminal domain Haspin_kinase PF12330.8 AIO02010.1 - 0.014 14.3 0.1 0.02 13.8 0.1 1.1 1 0 0 1 1 1 0 Haspin like kinase domain POR PF01558.18 AIO02010.1 - 0.081 13.0 0.0 0.14 12.2 0.0 1.3 1 0 0 1 1 1 0 Pyruvate ferredoxin/flavodoxin oxidoreductase Hydrolase_4 PF12146.8 AIO02011.1 - 7.8e-15 54.8 0.2 1.2e-09 37.8 0.2 2.2 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 AIO02011.1 - 1.4e-08 34.7 0.1 4.1e-06 26.6 0.1 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 AIO02011.1 - 1.4e-07 32.3 0.1 2.9e-07 31.3 0.1 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.16 AIO02011.1 - 5.3e-06 26.4 0.0 0.093 12.5 0.0 2.2 2 0 0 2 2 2 2 Phospholipase/Carboxylesterase Peptidase_S9 PF00326.21 AIO02011.1 - 1e-05 25.1 0.0 5.9e-05 22.6 0.0 2.0 1 1 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_3 PF07859.13 AIO02011.1 - 6.4e-05 22.9 0.6 0.00016 21.6 0.6 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold DLH PF01738.18 AIO02011.1 - 0.00032 20.3 0.0 0.025 14.2 0.0 2.1 1 1 1 2 2 2 1 Dienelactone hydrolase family AXE1 PF05448.12 AIO02011.1 - 0.00038 19.2 0.1 0.0042 15.8 0.0 2.1 2 1 0 2 2 2 1 Acetyl xylan esterase (AXE1) BAAT_C PF08840.11 AIO02011.1 - 0.00049 20.1 0.0 0.00082 19.3 0.0 1.3 1 0 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal Peptidase_S15 PF02129.18 AIO02011.1 - 0.00064 19.4 0.0 0.27 10.8 0.0 2.1 2 0 0 2 2 2 2 X-Pro dipeptidyl-peptidase (S15 family) DUF1100 PF06500.11 AIO02011.1 - 0.042 12.6 0.0 0.055 12.3 0.0 1.1 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1100) FSH1 PF03959.13 AIO02011.1 - 0.063 12.9 0.0 0.094 12.4 0.0 1.4 1 0 0 1 1 1 0 Serine hydrolase (FSH1) PGAP1 PF07819.13 AIO02011.1 - 0.2 11.4 0.2 0.62 9.7 0.2 1.8 1 1 0 1 1 1 0 PGAP1-like protein DEAD PF00270.29 AIO02012.1 - 1.5e-37 129.0 0.0 5.2e-37 127.3 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 AIO02012.1 - 2.9e-24 85.5 0.0 1.1e-23 83.7 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 AIO02012.1 - 7.1e-14 51.8 0.0 2.5e-13 50.0 0.0 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.15 AIO02012.1 - 0.00095 19.2 0.0 0.0026 17.8 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DnaJ PF00226.31 AIO02013.1 - 7e-15 54.9 0.0 4.7e-09 36.2 0.0 2.6 2 0 0 2 2 2 2 DnaJ domain HXXSHH PF07586.11 AIO02013.1 - 0.0011 18.6 0.9 0.0016 18.1 0.9 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1552) TFIIA PF03153.13 AIO02013.1 - 0.021 14.8 12.6 0.026 14.5 12.6 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit ARA70 PF12489.8 AIO02013.1 - 0.025 14.8 2.8 0.049 13.8 2.8 1.4 1 0 0 1 1 1 0 Nuclear coactivator Lin-8 PF03353.15 AIO02013.1 - 0.18 11.3 5.1 0.28 10.7 5.1 1.2 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist SRP-alpha_N PF04086.13 AIO02013.1 - 2 8.3 9.9 3 7.7 9.9 1.3 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal TORC_N PF12884.7 AIO02013.1 - 9.8 7.0 12.1 10 7.0 10.0 2.2 1 1 1 2 2 2 0 Transducer of regulated CREB activity, N terminus Pkinase PF00069.25 AIO02015.1 - 1.7e-38 132.5 0.0 1.4e-37 129.5 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 AIO02015.1 - 2.5e-21 76.1 0.0 3.1e-20 72.6 0.0 2.2 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 AIO02015.1 - 1.4e-08 34.5 0.0 2.4e-08 33.6 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 AIO02015.1 - 0.02 14.8 0.1 0.054 13.4 0.1 1.7 1 0 0 1 1 1 0 Phosphotransferase enzyme family zf-RING_4 PF14570.6 AIO02015.1 - 3.1 7.7 17.9 6.1 6.7 17.9 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain RIIa PF02197.17 AIO02016.1 - 4e-10 39.2 0.1 1.2e-09 37.6 0.1 1.9 1 0 0 1 1 1 1 Regulatory subunit of type II PKA R-subunit EF-hand_6 PF13405.6 AIO02016.1 - 2.1e-05 24.1 0.2 0.039 13.9 0.0 3.1 3 0 0 3 3 3 2 EF-hand domain EF-hand_7 PF13499.6 AIO02016.1 - 0.012 16.0 0.0 4.3 7.8 0.0 2.5 2 0 0 2 2 2 0 EF-hand domain pair EF-hand_1 PF00036.32 AIO02016.1 - 0.099 12.2 0.1 3.6 7.3 0.0 3.1 3 0 0 3 3 3 0 EF hand TPR_2 PF07719.17 AIO02017.1 - 7.7e-15 53.7 8.9 0.022 14.9 0.0 6.8 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_19 PF14559.6 AIO02017.1 - 4.4e-10 39.9 12.0 0.00028 21.3 0.4 5.1 3 2 2 5 5 5 3 Tetratricopeptide repeat TPR_14 PF13428.6 AIO02017.1 - 1.7e-09 37.7 14.4 0.00094 19.8 0.1 6.7 4 3 3 7 7 7 2 Tetratricopeptide repeat TPR_12 PF13424.6 AIO02017.1 - 1.2e-08 35.1 18.0 0.0019 18.4 0.0 5.5 4 2 2 6 6 6 4 Tetratricopeptide repeat TPR_1 PF00515.28 AIO02017.1 - 1.4e-06 27.8 8.8 0.9 9.5 1.7 5.9 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_7 PF13176.6 AIO02017.1 - 1.9e-05 24.3 13.1 0.022 14.8 0.0 5.1 5 1 0 5 5 4 2 Tetratricopeptide repeat TPR_8 PF13181.6 AIO02017.1 - 4.9e-05 23.2 6.3 4.5 7.7 1.4 6.1 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_15 PF13429.6 AIO02017.1 - 5.2e-05 22.6 4.9 0.0091 15.2 0.3 3.4 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_4 PF07721.14 AIO02017.1 - 5.9e-05 23.3 6.7 0.038 14.6 0.7 4.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.6 AIO02017.1 - 6.1e-05 23.1 3.2 0.98 9.9 0.0 4.8 4 1 0 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.6 AIO02017.1 - 0.00045 20.8 16.2 0.19 12.4 3.1 4.7 5 1 1 6 6 4 3 Tetratricopeptide repeat TPR_MalT PF17874.1 AIO02017.1 - 0.0011 18.5 11.0 0.0027 17.1 9.7 1.9 1 1 1 2 2 2 2 MalT-like TPR region TPR_6 PF13174.6 AIO02017.1 - 0.0012 19.4 6.9 0.9 10.3 0.0 5.1 6 0 0 6 6 5 1 Tetratricopeptide repeat DUF218 PF02698.17 AIO02017.1 - 0.0018 18.3 0.6 0.0061 16.6 0.2 2.0 2 1 0 2 2 2 1 DUF218 domain TPR_11 PF13414.6 AIO02017.1 - 0.038 13.7 8.8 12 5.7 1.0 5.6 5 1 1 6 6 6 0 TPR repeat ANAPC3 PF12895.7 AIO02017.1 - 0.042 14.1 10.7 2.2 8.5 1.9 3.8 2 1 2 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 MIT PF04212.18 AIO02017.1 - 0.43 10.7 8.8 0.47 10.6 0.6 3.5 3 0 0 3 3 3 0 MIT (microtubule interacting and transport) domain TPR_21 PF09976.9 AIO02017.1 - 2.4 7.8 6.5 15 5.3 0.2 2.9 1 1 2 3 3 3 0 Tetratricopeptide repeat-like domain TPR_10 PF13374.6 AIO02017.1 - 3.5 7.6 18.5 42 4.2 0.0 6.3 7 0 0 7 7 7 0 Tetratricopeptide repeat SF3b10 PF07189.11 AIO02019.1 - 2.6e-15 56.3 0.0 2.8e-15 56.2 0.0 1.0 1 0 0 1 1 1 1 Splicing factor 3B subunit 10 (SF3b10) SseB PF07179.12 AIO02020.1 - 0.15 12.3 0.0 28 5.0 0.0 2.5 2 0 0 2 2 2 0 SseB protein N-terminal domain HD_3 PF13023.6 AIO02021.1 - 1.4e-39 135.7 0.0 1.7e-39 135.4 0.0 1.1 1 0 0 1 1 1 1 HD domain HD_2 PF12917.7 AIO02021.1 - 6.4e-12 45.6 0.0 9.3e-12 45.1 0.0 1.2 1 0 0 1 1 1 1 HD containing hydrolase-like enzyme HD PF01966.22 AIO02021.1 - 3.7e-06 27.2 0.0 5.7e-06 26.6 0.0 1.3 1 0 0 1 1 1 1 HD domain RRM_1 PF00076.22 AIO02024.1 - 4e-72 238.0 0.0 6.2e-17 61.2 0.0 4.4 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP PF00658.18 AIO02024.1 - 2.3e-24 85.3 0.1 4.5e-24 84.4 0.1 1.5 1 0 0 1 1 1 1 Poly-adenylate binding protein, unique domain RRM_occluded PF16842.5 AIO02024.1 - 4.2e-09 36.1 0.0 0.099 12.5 0.0 3.8 4 0 0 4 4 4 3 Occluded RNA-recognition motif RRM_3 PF08777.11 AIO02024.1 - 4.7e-08 33.0 4.5 0.19 11.8 0.6 4.4 3 1 1 4 4 4 3 RNA binding motif Nup35_RRM_2 PF14605.6 AIO02024.1 - 2.1e-07 30.8 0.0 0.056 13.5 0.0 4.0 4 0 0 4 4 4 2 Nup53/35/40-type RNA recognition motif RRM_7 PF16367.5 AIO02024.1 - 2.2e-05 24.5 0.1 0.26 11.4 0.0 5.0 5 3 0 5 5 5 1 RNA recognition motif RRM_5 PF13893.6 AIO02024.1 - 0.00051 19.6 0.0 0.016 14.8 0.0 2.8 2 1 1 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.8 AIO02024.1 - 0.041 13.9 0.7 1.6 8.9 0.0 3.3 3 1 0 3 3 3 0 Limkain b1 RRM_8 PF11835.8 AIO02024.1 - 0.048 13.9 0.0 17 5.7 0.0 2.7 2 0 0 2 2 2 0 RRM-like domain TB2_DP1_HVA22 PF03134.19 AIO02025.1 - 0.052 13.5 0.9 0.052 13.5 0.9 1.7 2 0 0 2 2 2 0 TB2/DP1, HVA22 family GTP_EFTU PF00009.27 AIO02026.1 - 1.3e-42 145.5 0.0 2.5e-40 138.1 0.0 2.2 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 AIO02026.1 - 7.8e-14 51.9 0.0 1.6e-13 50.9 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain MMR_HSR1 PF01926.23 AIO02026.1 - 0.0019 18.3 0.1 0.0074 16.4 0.1 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase DUF2009 PF09418.10 AIO02027.1 - 1.3e-174 581.6 0.0 1.4e-174 581.4 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2009) RNA_pol_Rpc4 PF05132.14 AIO02028.1 - 1.3e-07 32.2 0.0 3.8e-07 30.6 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase III RPC4 BBS1 PF14779.6 AIO02029.1 - 2.3e-79 266.4 0.0 4.4e-79 265.5 0.0 1.5 1 0 0 1 1 1 1 Ciliary BBSome complex subunit 1 PHTB1_N PF14727.6 AIO02029.1 - 0.00057 19.3 0.0 0.0046 16.4 0.0 2.4 3 0 0 3 3 3 1 PTHB1 N-terminus BBS2_Mid PF14783.6 AIO02029.1 - 0.012 15.6 0.0 4.5 7.4 0.0 3.3 3 1 0 3 3 3 0 Ciliary BBSome complex subunit 2, middle region VMA21 PF09446.10 AIO02030.1 - 1.3e-05 25.2 9.6 1.9e-05 24.7 9.6 1.2 1 0 0 1 1 1 1 VMA21-like domain BPD_transp_1 PF00528.22 AIO02030.1 - 0.09 12.5 2.9 0.13 11.9 2.9 1.2 1 0 0 1 1 1 0 Binding-protein-dependent transport system inner membrane component TssN PF17555.2 AIO02030.1 - 0.17 11.3 2.9 0.29 10.5 3.0 1.4 1 1 0 1 1 1 0 Type VI secretion system, TssN SOG2 PF10428.9 AIO02030.1 - 1 8.5 6.4 1.2 8.2 6.4 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein Syja_N PF02383.18 AIO02032.1 - 4.9e-22 78.6 0.0 2.3e-21 76.5 0.0 1.9 1 1 0 1 1 1 1 SacI homology domain Methyltransf_23 PF13489.6 AIO02034.1 - 4.2e-19 69.0 0.0 5.5e-19 68.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 AIO02034.1 - 4.6e-18 65.7 0.0 7.4e-18 65.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 AIO02034.1 - 6.3e-16 58.5 0.0 1.3e-15 57.5 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 AIO02034.1 - 4.5e-15 56.1 0.0 9.9e-15 55.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 AIO02034.1 - 2.2e-12 47.5 0.0 6.3e-12 46.1 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 AIO02034.1 - 4.1e-08 32.9 0.0 1.3e-07 31.2 0.0 1.7 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_32 PF13679.6 AIO02034.1 - 6.8e-07 29.4 0.0 1e-06 28.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 AIO02034.1 - 2.6e-06 27.1 0.1 3.8e-06 26.5 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) NodS PF05401.11 AIO02034.1 - 5.6e-06 26.1 0.3 2.8e-05 23.8 0.3 1.8 1 1 0 1 1 1 1 Nodulation protein S (NodS) MTS PF05175.14 AIO02034.1 - 7.9e-05 22.3 0.1 0.00017 21.2 0.1 1.6 1 1 0 1 1 1 1 Methyltransferase small domain Pox_MCEL PF03291.16 AIO02034.1 - 0.0009 18.4 0.0 0.0013 17.9 0.0 1.2 1 0 0 1 1 1 1 mRNA capping enzyme Ubie_methyltran PF01209.18 AIO02034.1 - 0.0011 18.4 0.0 0.0018 17.6 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family PCMT PF01135.19 AIO02034.1 - 0.004 16.9 0.1 0.006 16.4 0.1 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MetW PF07021.12 AIO02034.1 - 0.0096 15.5 0.9 0.2 11.2 0.1 2.4 3 0 0 3 3 3 1 Methionine biosynthesis protein MetW TPMT PF05724.11 AIO02034.1 - 0.025 14.3 0.0 0.039 13.6 0.0 1.2 1 0 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) TehB PF03848.14 AIO02034.1 - 0.045 13.1 0.0 0.11 11.9 0.0 1.7 1 1 0 1 1 1 0 Tellurite resistance protein TehB FYVE PF01363.21 AIO02035.1 - 4.9e-16 58.6 14.1 3.8e-15 55.8 7.4 2.5 2 0 0 2 2 2 2 FYVE zinc finger C1_1 PF00130.22 AIO02035.1 - 0.063 13.2 8.6 0.086 12.7 3.7 2.3 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) DZR PF12773.7 AIO02035.1 - 0.3 11.1 17.2 0.76 9.9 9.5 3.3 1 1 0 2 2 2 0 Double zinc ribbon zf-C3HC4_3 PF13920.6 AIO02035.1 - 1.4 8.9 21.0 0.18 11.7 0.7 3.1 3 1 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) SRP-alpha_N PF04086.13 AIO02035.1 - 1.5 8.7 26.7 2 8.3 26.7 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal DUF3584 PF12128.8 AIO02035.1 - 5.1 4.5 40.1 6.3 4.2 40.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Rhodanese_C PF12368.8 AIO02035.1 - 5.5 7.5 15.4 7.8 7.0 8.9 2.5 1 1 1 2 2 2 0 Rhodanase C-terminal Asp-B-Hydro_N PF05279.11 AIO02035.1 - 6.1 6.8 33.4 8.1 6.4 33.4 1.2 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Hid1 PF12722.7 AIO02035.1 - 8.5 4.4 21.4 11 4.0 21.4 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein zf-HIT PF04438.16 AIO02035.1 - 9.6 6.2 15.3 7.5 6.5 2.5 2.5 2 0 0 2 2 2 0 HIT zinc finger Zn_ribbon_SprT PF17283.2 AIO02035.1 - 9.7 6.2 14.5 4.4 7.3 6.6 3.1 2 1 0 2 2 2 0 SprT-like zinc ribbon domain DUF3138 PF11336.8 AIO02035.1 - 9.9 4.6 9.1 14 4.2 9.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) SAS-6_N PF16531.5 AIO02037.1 - 7.6e-19 68.1 0.0 1.9e-18 66.8 0.0 1.7 1 0 0 1 1 1 1 Centriolar protein SAS N-terminal DUF2935 PF11155.8 AIO02037.1 - 0.042 14.2 8.7 0.1 12.9 0.5 3.6 2 2 0 2 2 2 0 Domain of unknown function (DUF2935) DUF16 PF01519.16 AIO02037.1 - 4.4 7.9 32.3 0.021 15.3 5.5 4.2 1 1 1 3 3 3 0 Protein of unknown function DUF16 DUF2353 PF09789.9 AIO02039.1 - 0.036 13.4 4.3 0.015 14.7 1.7 1.5 2 0 0 2 2 2 0 Uncharacterized coiled-coil protein (DUF2353) DUF4633 PF15464.6 AIO02039.1 - 1 9.5 5.3 0.61 10.2 0.5 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4633) Cyclin_C PF02984.19 AIO02040.1 - 0.62 10.2 4.2 2.3 8.3 0.8 2.1 1 1 1 2 2 2 0 Cyclin, C-terminal domain Hydrolase_6 PF13344.6 AIO02041.1 - 9.7e-25 86.6 0.0 2e-24 85.6 0.0 1.6 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 AIO02041.1 - 1.3e-13 50.8 0.0 3.2e-13 49.5 0.0 1.7 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.26 AIO02041.1 - 0.0026 18.1 0.0 0.018 15.3 0.0 2.4 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase PIH1 PF08190.12 AIO02042.1 - 1.6e-60 203.4 0.1 2.9e-60 202.5 0.1 1.4 1 0 0 1 1 1 1 PIH1 N-terminal domain PIH1_CS PF18201.1 AIO02042.1 - 2.2e-23 82.5 0.0 4.4e-23 81.6 0.0 1.5 1 0 0 1 1 1 1 PIH1 CS-like domain Mo25 PF08569.11 AIO02043.1 - 0.014 14.8 0.1 0.023 14.1 0.1 1.3 1 0 0 1 1 1 0 Mo25-like PGAP1 PF07819.13 AIO02044.1 - 6.6e-12 45.7 0.0 0.00016 21.5 0.0 3.2 3 2 0 3 3 3 2 PGAP1-like protein Hydrolase_4 PF12146.8 AIO02044.1 - 0.015 14.5 0.0 0.037 13.3 0.0 1.6 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 AIO02044.1 - 0.017 14.8 0.0 0.065 12.9 0.0 2.0 2 0 0 2 2 2 0 alpha/beta hydrolase fold DNA_pol_B_exo1 PF03104.19 AIO02045.1 - 9.9e-57 192.6 0.1 2.2e-56 191.5 0.0 1.6 2 0 0 2 2 2 1 DNA polymerase family B, exonuclease domain DUF1744 PF08490.12 AIO02045.1 - 2.8e-51 174.4 0.0 3e-50 171.0 0.0 2.2 1 1 0 1 1 1 1 Domain of unknown function (DUF1744) DNA_pol_B PF00136.21 AIO02045.1 - 8.5e-13 47.8 0.4 3.1e-10 39.4 0.3 3.8 3 1 0 3 3 3 1 DNA polymerase family B DNA_pol_B_exo2 PF10108.9 AIO02045.1 - 1.9e-10 40.8 0.1 3.3e-08 33.5 0.1 2.4 2 0 0 2 2 2 2 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB RNase_H_2 PF13482.6 AIO02045.1 - 1.4e-07 31.6 0.2 4.6e-07 30.0 0.1 2.0 2 0 0 2 2 2 1 RNase_H superfamily G2BR PF18442.1 AIO02045.1 - 0.059 13.0 1.7 0.34 10.6 1.7 2.3 1 0 0 1 1 1 0 E3 gp78 Ube2g2-binding region (G2BR) YopE_N PF09020.10 AIO02045.1 - 0.1 12.8 0.0 0.33 11.2 0.0 1.8 2 0 0 2 2 2 0 YopE, N terminal zf-3CxxC PF13695.6 AIO02046.1 - 3.1e-06 27.6 2.5 3.6e-06 27.4 2.5 1.2 1 0 0 1 1 1 1 Zinc-binding domain zf-3CxxC_2 PF17180.4 AIO02046.1 - 0.003 18.3 7.2 0.0053 17.5 7.0 1.5 1 1 0 1 1 1 1 Zinc-binding domain zinc_ribbon_4 PF13717.6 AIO02046.1 - 0.054 13.4 1.9 0.054 13.4 1.9 2.3 2 0 0 2 2 2 0 zinc-ribbon domain HC2 PF07382.11 AIO02047.1 - 4.4e-07 30.2 14.3 0.00011 22.4 9.7 2.1 1 1 1 2 2 2 2 Histone H1-like nucleoprotein HC2 DTHCT PF08070.11 AIO02047.1 - 0.00026 21.7 47.7 0.25 12.1 10.9 3.5 1 1 2 3 3 3 3 DTHCT (NUC029) region LisH PF08513.11 AIO02047.1 - 0.27 11.3 0.4 0.39 10.8 0.4 1.2 1 0 0 1 1 1 0 LisH TPR_12 PF13424.6 AIO02048.1 - 4.2e-05 23.7 12.9 0.14 12.5 0.5 4.2 4 0 0 4 4 4 3 Tetratricopeptide repeat Snf7 PF03357.21 AIO02049.1 - 7.2e-13 48.5 20.3 7.2e-13 48.5 20.3 1.7 1 1 1 2 2 2 1 Snf7 Mating_C PF12737.7 AIO02049.1 - 0.57 9.3 3.6 0.11 11.8 0.3 1.6 2 1 0 2 2 2 0 C-terminal domain of homeodomain 1 PIN_8 PF18476.1 AIO02049.1 - 8.5 6.2 11.7 0.95 9.3 5.8 1.9 1 1 1 2 2 2 0 PIN like domain AA_permease_2 PF13520.6 AIO02050.1 - 5.1e-38 131.0 48.8 6.6e-38 130.6 48.8 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 AIO02050.1 - 2.7e-05 22.9 43.2 5.2e-05 22.0 43.2 1.5 1 1 0 1 1 1 1 Amino acid permease Mito_carr PF00153.27 AIO02051.1 - 3.1e-30 103.9 7.7 3.9e-16 58.8 0.1 3.5 3 1 0 3 3 3 3 Mitochondrial carrier protein ArsB PF02040.15 AIO02051.1 - 0.043 13.1 0.2 0.063 12.6 0.2 1.2 1 0 0 1 1 1 0 Arsenical pump membrane protein zf-CCCH_3 PF15663.5 AIO02053.1 - 0.033 14.4 0.0 0.07 13.3 0.0 1.5 1 0 0 1 1 1 0 Zinc-finger containing family zf-CCCH_2 PF14608.6 AIO02053.1 - 0.072 13.6 6.1 0.14 12.6 6.1 1.5 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger zf-CCCH_4 PF18044.1 AIO02053.1 - 0.073 12.9 7.0 0.35 10.7 7.0 2.1 1 1 0 1 1 1 0 CCCH-type zinc finger zf-CCCH PF00642.24 AIO02053.1 - 0.29 11.1 2.6 0.62 10.0 2.6 1.5 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 AIO02053.1 - 1.6 8.9 8.0 1.3 9.2 1.6 2.4 2 0 0 2 2 2 0 Zinc finger domain LSM PF01423.22 AIO02054.1 - 1.3e-19 69.6 0.0 1.5e-19 69.4 0.0 1.0 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 AIO02054.1 - 0.00037 20.6 0.0 0.00039 20.5 0.0 1.1 1 0 0 1 1 1 1 Ataxin 2 SM domain LSM14 PF12701.7 AIO02054.1 - 0.12 12.5 0.0 0.13 12.4 0.0 1.2 1 0 0 1 1 1 0 Scd6-like Sm domain CS PF04969.16 AIO02055.1 - 3.7e-10 40.7 0.1 5.2e-10 40.2 0.1 1.2 1 0 0 1 1 1 1 CS domain ARL2_Bind_BART PF11527.8 AIO02056.1 - 1.2e-08 35.1 0.3 1.6e-08 34.7 0.3 1.2 1 0 0 1 1 1 1 The ARF-like 2 binding protein BART BRAP2 PF07576.12 AIO02056.1 - 0.066 13.4 0.0 0.099 12.9 0.0 1.3 1 0 0 1 1 1 0 BRCA1-associated protein 2 zf-ANAPC11 PF12861.7 AIO02057.1 - 6.2e-29 99.9 10.2 6.8e-29 99.8 10.2 1.0 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.7 AIO02057.1 - 2.4e-18 66.1 12.4 3.3e-18 65.7 12.4 1.2 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 AIO02057.1 - 1.1e-06 28.3 17.7 1.3e-05 24.9 7.9 2.3 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 AIO02057.1 - 3.3e-06 27.3 21.0 8e-05 22.9 19.6 2.6 1 1 1 2 2 2 1 Ring finger domain zf-RING_UBOX PF13445.6 AIO02057.1 - 2.5e-05 24.2 12.3 5.5e-05 23.1 12.3 1.6 1 1 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 AIO02057.1 - 0.00027 20.7 17.1 0.00032 20.5 15.6 2.0 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 AIO02057.1 - 0.00049 20.0 18.9 0.0043 17.0 17.6 2.5 1 1 1 2 2 2 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 AIO02057.1 - 0.0017 18.2 17.5 0.086 12.7 10.9 2.7 1 1 1 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.6 AIO02057.1 - 0.0031 17.3 3.1 0.0031 17.3 3.1 2.8 1 1 1 2 2 2 1 RING/Ubox like zinc-binding domain Zn_ribbon_17 PF17120.5 AIO02057.1 - 0.0054 16.3 5.1 0.0054 16.3 5.1 1.8 1 1 1 2 2 2 1 Zinc-ribbon, C4HC2 type zf-RING_11 PF17123.5 AIO02057.1 - 0.0066 16.2 15.0 0.23 11.3 15.0 2.5 1 1 0 1 1 1 1 RING-like zinc finger zf-C3HC4_4 PF15227.6 AIO02057.1 - 0.021 15.0 4.4 0.021 15.0 4.4 2.5 2 1 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-HIT PF04438.16 AIO02057.1 - 0.32 10.9 10.9 0.65 9.9 5.9 2.4 2 1 0 2 2 2 0 HIT zinc finger zf-Nse PF11789.8 AIO02057.1 - 0.87 9.5 10.3 1.4 8.8 10.3 1.4 1 1 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit PHD PF00628.29 AIO02057.1 - 4.2 7.4 15.0 65 3.5 15.0 2.5 1 1 0 1 1 1 0 PHD-finger zf-RING-like PF08746.11 AIO02057.1 - 9 6.7 17.3 85 3.6 17.3 2.4 1 1 0 1 1 1 0 RING-like domain DUF2833 PF11090.8 AIO02058.1 - 0.034 14.5 0.0 0.057 13.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2833) DUF962 PF06127.11 AIO02059.1 - 2.2e-21 75.7 2.3 4.9e-21 74.6 2.3 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF962) FPL PF09758.9 AIO02061.1 - 1.8e-51 174.0 1.8 3.4e-51 173.1 1.8 1.5 1 0 0 1 1 1 1 Uncharacterised conserved protein DNA_pol3_tau_5 PF12170.8 AIO02061.1 - 0.0024 17.9 2.9 0.93 9.5 0.1 2.5 2 0 0 2 2 2 2 DNA polymerase III tau subunit V interacting with alpha SET PF00856.28 AIO02062.1 - 2.4e-36 125.7 0.1 7.6e-06 26.4 0.0 8.8 7 2 0 7 7 7 5 SET domain SAF PF08666.12 AIO02062.1 - 0.00033 21.2 0.0 1.9e+02 2.7 0.0 8.4 11 0 0 11 11 11 0 SAF domain 60KD_IMP PF02096.20 AIO02065.1 - 0.00044 20.2 0.0 0.00065 19.6 0.0 1.3 1 0 0 1 1 1 1 60Kd inner membrane protein PS_Dcarbxylase PF02666.15 AIO02066.1 - 2.3e-38 131.8 0.0 2.9e-38 131.4 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase DUF3361 PF11841.8 AIO02067.1 - 0.048 13.6 1.6 8.1 6.4 0.0 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF3361) DUF4055 PF13264.6 AIO02067.1 - 0.56 10.4 6.9 2.2 8.4 0.1 3.7 3 1 0 3 3 3 0 Domain of unknown function (DUF4055) GIT_CC PF16559.5 AIO02067.1 - 0.88 9.5 5.7 16 5.5 4.4 3.2 2 0 0 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor Lebercilin PF15619.6 AIO02067.1 - 9.4 5.8 46.2 0.96 9.1 2.6 5.5 4 2 1 5 5 5 0 Ciliary protein causing Leber congenital amaurosis disease Pkinase PF00069.25 AIO02069.1 - 1.3e-11 44.4 0.0 4.9e-11 42.5 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 AIO02069.1 - 0.0002 20.8 0.0 0.00035 19.9 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase DnaJ PF00226.31 AIO02070.1 - 1.1e-13 51.1 0.2 2.2e-13 50.1 0.2 1.5 1 0 0 1 1 1 1 DnaJ domain DUF3613 PF12266.8 AIO02070.1 - 0.023 14.4 0.1 0.12 12.2 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3613) DUF4266 PF14086.6 AIO02070.1 - 0.21 12.6 0.1 0.48 11.4 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4266) Cgr1 PF03879.14 AIO02071.1 - 7e-06 26.4 22.4 8.9e-06 26.0 22.4 1.2 1 0 0 1 1 1 1 Cgr1 family Med8 PF10232.9 AIO02071.1 - 0.0051 16.4 5.2 0.0059 16.2 5.2 1.1 1 0 0 1 1 1 1 Mediator of RNA polymerase II transcription complex subunit 8 LPP20 PF02169.16 AIO02071.1 - 0.023 15.0 1.2 0.027 14.8 1.2 1.2 1 0 0 1 1 1 0 LPP20 lipoprotein FAM178 PF14816.6 AIO02071.1 - 0.2 10.6 4.8 0.22 10.4 4.8 1.1 1 0 0 1 1 1 0 Family of unknown function, FAM178 AAA_11 PF13086.6 AIO02071.1 - 0.21 11.4 11.2 0.22 11.3 11.2 1.0 1 0 0 1 1 1 0 AAA domain Atg14 PF10186.9 AIO02071.1 - 4.7 6.2 16.0 5 6.1 16.0 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DSPc PF00782.20 AIO02072.1 - 3.6e-20 72.1 0.0 5.4e-20 71.5 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 AIO02072.1 - 0.011 15.3 0.0 0.016 14.8 0.0 1.2 1 0 0 1 1 1 0 Protein-tyrosine phosphatase zf-SNAP50_C PF12251.8 AIO02073.1 - 5e-37 127.5 0.1 7.4e-37 127.0 0.1 1.2 1 0 0 1 1 1 1 snRNA-activating protein of 50kDa MW C terminal Katanin_con80 PF13925.6 AIO02074.1 - 1.1e-27 97.1 0.0 1.4e-27 96.7 0.0 1.2 1 0 0 1 1 1 1 con80 domain of Katanin WD40 PF00400.32 AIO02074.1 - 8.8e-27 92.8 7.9 2.6e-06 28.0 0.4 5.7 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 AIO02074.1 - 1.6e-14 54.0 0.0 8.5e-07 29.2 0.0 3.7 1 1 1 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 AIO02074.1 - 0.00044 19.7 0.0 0.02 14.2 0.0 2.4 1 1 1 2 2 2 1 WD40-like domain eIF2A PF08662.11 AIO02074.1 - 0.003 17.5 0.0 2.2 8.1 0.0 2.5 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 AIO02074.1 - 0.064 12.2 0.0 0.71 8.8 0.0 2.4 1 1 1 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Frtz PF11768.8 AIO02074.1 - 0.15 10.3 0.0 1.4 7.2 0.0 2.0 2 0 0 2 2 2 0 WD repeat-containing and planar cell polarity effector protein Fritz Nup160 PF11715.8 AIO02074.1 - 0.19 10.3 0.4 0.95 8.0 0.1 2.3 1 1 1 3 3 3 0 Nucleoporin Nup120/160 ParcG PF10274.9 AIO02075.1 - 4.9e-74 248.4 0.0 6.1e-74 248.1 0.0 1.1 1 0 0 1 1 1 1 Parkin co-regulated protein Kinesin PF00225.23 AIO02076.1 - 4.3e-56 190.3 1.0 1.1e-55 188.9 1.0 1.6 1 1 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 AIO02076.1 - 1.5e-08 34.7 0.0 3.1e-08 33.7 0.0 1.5 1 0 0 1 1 1 1 Microtubule binding AAA_16 PF13191.6 AIO02076.1 - 0.0077 16.6 0.1 0.02 15.3 0.1 1.6 1 1 0 1 1 1 1 AAA ATPase domain DUF87 PF01935.17 AIO02076.1 - 0.052 13.6 0.1 0.31 11.1 0.0 2.2 2 0 0 2 2 2 0 Helicase HerA, central domain AAA_22 PF13401.6 AIO02076.1 - 0.12 12.6 0.5 0.3 11.3 0.5 1.9 1 1 0 1 1 1 0 AAA domain HSP70 PF00012.20 AIO02077.1 - 2.5e-61 207.6 0.0 5.1e-61 206.6 0.0 1.5 1 1 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 AIO02077.1 - 0.0047 15.8 0.0 0.023 13.5 0.0 2.1 2 0 0 2 2 2 1 MreB/Mbl protein GCV_H PF01597.19 AIO02078.1 - 3.8e-40 136.6 1.0 4.3e-40 136.4 1.0 1.0 1 0 0 1 1 1 1 Glycine cleavage H-protein Biotin_lipoyl PF00364.22 AIO02078.1 - 1.1e-06 28.4 0.3 2e-06 27.5 0.3 1.4 1 0 0 1 1 1 1 Biotin-requiring enzyme PTS_EIIA_1 PF00358.20 AIO02078.1 - 6.5e-05 22.7 0.1 9.5e-05 22.2 0.1 1.2 1 0 0 1 1 1 1 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 RnfC_N PF13375.6 AIO02078.1 - 0.00016 21.6 0.3 0.00024 21.0 0.3 1.2 1 0 0 1 1 1 1 RnfC Barrel sandwich hybrid domain MS_channel PF00924.18 AIO02078.1 - 0.098 12.2 0.0 0.14 11.7 0.0 1.2 1 0 0 1 1 1 0 Mechanosensitive ion channel Gp_dh_N PF00044.24 AIO02079.1 - 2.9e-15 56.4 0.0 5.7e-15 55.5 0.0 1.5 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain Gp_dh_C PF02800.20 AIO02079.1 - 1.4e-13 50.7 0.1 2.3e-13 50.0 0.1 1.3 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain DUF1761 PF08570.10 AIO02080.1 - 0.13 12.6 3.8 0.22 11.8 3.8 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1761) Pro_isomerase PF00160.21 AIO02081.1 - 2.6e-46 157.8 0.5 4.6e-46 157.0 0.5 1.4 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD TPR_2 PF07719.17 AIO02081.1 - 4.8e-07 29.4 0.2 0.078 13.1 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 AIO02081.1 - 3.4e-06 26.6 0.1 0.081 12.8 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_9 PF13371.6 AIO02081.1 - 0.00048 20.2 0.5 0.0011 19.1 0.5 1.5 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_6 PF13174.6 AIO02081.1 - 0.0026 18.3 0.2 3 8.7 0.0 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.6 AIO02081.1 - 0.0037 17.7 1.7 2.8 8.5 0.1 2.9 1 1 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.6 AIO02081.1 - 0.0073 16.4 0.3 1.4 9.3 0.0 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat ANAPC3 PF12895.7 AIO02081.1 - 0.02 15.1 1.4 0.28 11.5 0.2 2.5 1 1 1 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 Coatomer_E PF04733.14 AIO02081.1 - 0.023 14.1 1.4 0.03 13.7 0.7 1.5 1 1 0 1 1 1 0 Coatomer epsilon subunit TPR_16 PF13432.6 AIO02081.1 - 0.027 15.1 1.2 0.091 13.4 0.9 2.1 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.6 AIO02081.1 - 0.032 15.0 1.6 0.31 12.0 0.3 2.9 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.6 AIO02081.1 - 0.037 14.3 1.3 0.86 9.9 0.7 2.6 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_17 PF13431.6 AIO02081.1 - 0.11 13.0 0.0 0.97 10.0 0.0 2.5 3 0 0 3 3 3 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 AIO02081.1 - 0.94 9.6 2.8 4.4 7.5 0.1 2.7 3 0 0 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat SCAMP PF04144.13 AIO02083.1 - 2.5e-37 128.9 15.7 2.9e-37 128.7 15.7 1.0 1 0 0 1 1 1 1 SCAMP family CPP1-like PF11833.8 AIO02083.1 - 0.13 11.9 2.4 0.53 9.9 0.0 2.1 2 0 0 2 2 2 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like DUF1129 PF06570.11 AIO02083.1 - 0.14 11.6 9.9 0.33 10.4 9.8 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1129) ThrE PF06738.12 AIO02083.1 - 8.5 5.7 14.3 2.4 7.5 3.1 2.2 2 0 0 2 2 2 0 Putative threonine/serine exporter A_deaminase PF00962.22 AIO02084.1 - 5.4e-117 390.8 0.0 8.3e-87 291.6 0.0 2.4 2 0 0 2 2 2 2 Adenosine/AMP deaminase BRCT_2 PF16589.5 AIO02085.1 - 1.5e-06 28.5 0.0 1.9e-05 25.0 0.0 2.2 2 0 0 2 2 2 1 BRCT domain, a BRCA1 C-terminus domain BRCT PF00533.26 AIO02085.1 - 0.00055 20.3 0.0 0.022 15.1 0.0 2.6 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain zf-C3HC4_3 PF13920.6 AIO02085.1 - 0.018 14.9 4.4 0.82 9.6 0.3 2.4 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) LIG3_BRCT PF16759.5 AIO02085.1 - 0.12 12.7 0.0 0.37 11.1 0.0 1.9 1 0 0 1 1 1 0 DNA ligase 3 BRCT domain Cript PF10235.9 AIO02085.1 - 0.29 11.7 4.1 0.22 12.1 0.7 2.3 2 0 0 2 2 2 0 Microtubule-associated protein CRIPT Zf_RING PF16744.5 AIO02085.1 - 0.78 9.9 5.2 2.4 8.4 1.7 2.6 2 0 0 2 2 2 0 KIAA1045 RING finger His_Phos_1 PF00300.22 AIO02086.1 - 1.3e-10 41.3 0.0 0.00031 20.5 0.0 3.3 3 1 0 3 3 3 3 Histidine phosphatase superfamily (branch 1) Nitrate_red_del PF02613.15 AIO02088.1 - 0.039 14.0 0.0 0.13 12.3 0.0 2.0 1 1 0 1 1 1 0 Nitrate reductase delta subunit Proteasome PF00227.26 AIO02089.1 - 8.8e-38 129.7 0.0 1.3e-37 129.2 0.0 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 AIO02089.1 - 1.5e-11 43.8 0.2 1.5e-11 43.8 0.2 1.9 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature FAM184 PF15665.5 AIO02091.1 - 0.0041 16.9 16.1 0.0041 16.9 16.1 9.4 1 1 8 9 9 9 6 Family with sequence similarity 184, A and B TPR_1 PF00515.28 AIO02092.1 - 2.4e-12 46.1 9.6 2.4e-05 24.0 0.1 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 AIO02092.1 - 1.5e-08 34.1 6.8 1e-07 31.5 0.8 2.5 1 1 1 2 2 2 1 TPR repeat TPR_2 PF07719.17 AIO02092.1 - 3e-08 33.1 19.0 0.00054 19.9 0.1 4.0 3 1 1 4 4 3 2 Tetratricopeptide repeat UPF0121 PF03661.13 AIO02092.1 - 1.1e-05 24.9 9.8 0.00015 21.3 9.8 2.0 1 1 0 1 1 1 1 Uncharacterised protein family (UPF0121) TPR_17 PF13431.6 AIO02092.1 - 3.3e-05 23.9 1.3 3.3e-05 23.9 1.3 2.1 2 0 0 2 2 1 1 Tetratricopeptide repeat TPR_8 PF13181.6 AIO02092.1 - 5e-05 23.2 6.6 0.011 15.9 1.7 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 AIO02092.1 - 0.00017 21.8 5.3 0.0039 17.4 2.6 2.4 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.6 AIO02092.1 - 0.00018 22.1 0.5 0.00018 22.1 0.5 2.6 3 0 0 3 3 2 1 Tetratricopeptide repeat TPR_7 PF13176.6 AIO02092.1 - 0.011 15.7 0.9 0.76 10.0 0.2 2.8 3 0 0 3 3 2 0 Tetratricopeptide repeat Tap-RNA_bind PF09162.10 AIO02092.1 - 0.065 13.1 0.1 0.19 11.6 0.1 1.7 1 0 0 1 1 1 0 Tap, RNA-binding ANAPC3 PF12895.7 AIO02092.1 - 0.29 11.4 2.8 0.54 10.5 2.8 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_10 PF13374.6 AIO02092.1 - 0.36 10.8 8.2 1.5 8.8 2.3 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 AIO02092.1 - 0.92 10.5 7.4 8.6 7.5 0.1 4.0 2 1 2 4 4 4 0 Tetratricopeptide repeat Rad51 PF08423.11 AIO02093.1 - 3.9e-122 406.4 0.0 5e-122 406.1 0.0 1.1 1 0 0 1 1 1 1 Rad51 RecA PF00154.21 AIO02093.1 - 1.4e-12 47.7 0.2 1.8e-12 47.3 0.2 1.1 1 0 0 1 1 1 1 recA bacterial DNA recombination protein HHH_5 PF14520.6 AIO02093.1 - 7.8e-08 32.8 1.0 2.2e-07 31.4 0.6 1.9 2 0 0 2 2 2 1 Helix-hairpin-helix domain ATPase PF06745.13 AIO02093.1 - 6.6e-07 28.9 0.1 1.3e-06 28.0 0.1 1.5 1 1 0 1 1 1 1 KaiC AAA_25 PF13481.6 AIO02093.1 - 1.2e-06 28.3 0.0 3.4e-06 26.8 0.0 1.7 2 0 0 2 2 2 1 AAA domain DnaB_C PF03796.15 AIO02093.1 - 0.07 12.4 0.1 0.15 11.4 0.1 1.5 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain AAA_24 PF13479.6 AIO02093.1 - 0.12 12.1 0.0 0.22 11.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain MCM PF00493.23 AIO02095.1 - 2.6e-58 196.8 0.0 4.1e-58 196.1 0.0 1.2 1 0 0 1 1 1 1 MCM P-loop domain MCM_lid PF17855.1 AIO02095.1 - 3.8e-15 56.1 0.0 1.3e-14 54.4 0.0 1.9 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_OB PF17207.3 AIO02095.1 - 4.3e-12 46.0 1.3 8.6e-12 45.0 1.3 1.4 1 0 0 1 1 1 1 MCM OB domain AAA_5 PF07728.14 AIO02095.1 - 0.00027 21.0 0.0 0.0014 18.6 0.0 2.1 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 AIO02095.1 - 0.00053 19.4 0.0 0.034 13.5 0.0 2.5 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 AIO02095.1 - 0.014 15.3 0.0 0.038 13.9 0.0 1.8 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) TTL PF03133.15 AIO02096.1 - 4.9e-76 255.7 0.0 7.7e-76 255.0 0.0 1.2 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 AIO02096.1 - 0.00028 20.2 0.0 0.0027 17.0 0.0 2.3 2 1 0 2 2 2 1 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 AIO02096.1 - 0.094 11.9 0.0 2.3 7.4 0.0 2.1 2 0 0 2 2 2 0 Sugar-transfer associated ATP-grasp zf-CCCH_4 PF18044.1 AIO02098.1 - 0.0011 18.7 4.1 0.0018 18.1 4.1 1.3 1 0 0 1 1 1 1 CCCH-type zinc finger zf-CCCH PF00642.24 AIO02098.1 - 0.0037 17.1 4.2 0.0072 16.2 4.2 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.6 AIO02098.1 - 0.032 14.7 3.1 0.057 13.9 3.1 1.4 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger zf_CCCH_4 PF18345.1 AIO02098.1 - 0.37 10.9 5.5 0.65 10.1 5.5 1.4 1 0 0 1 1 1 0 Zinc finger domain Keratin_2_head PF16208.5 AIO02099.1 - 0.27 11.4 18.0 0.39 10.9 18.0 1.3 1 0 0 1 1 1 0 Keratin type II head PAP2_C PF14360.6 AIO02101.1 - 6e-20 71.5 8.7 6e-20 71.5 8.7 2.0 2 0 0 2 2 2 1 PAP2 superfamily C-terminal PAP2 PF01569.21 AIO02101.1 - 0.19 11.5 10.9 0.11 12.3 8.4 1.9 2 1 0 2 2 2 0 PAP2 superfamily PSP1 PF04468.12 AIO02102.1 - 1.2e-18 67.1 0.6 1.8e-18 66.6 0.6 1.2 1 0 0 1 1 1 1 PSP1 C-terminal conserved region Pkinase PF00069.25 AIO02103.1 - 5.8e-68 229.1 0.0 7.1e-68 228.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 AIO02103.1 - 5.2e-30 104.6 0.0 2e-29 102.7 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 AIO02103.1 - 2.3e-06 27.2 0.1 0.00014 21.3 0.0 2.2 1 1 0 2 2 2 1 Kinase-like FTA2 PF13095.6 AIO02103.1 - 0.013 15.1 0.1 0.048 13.3 0.1 1.9 1 1 1 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 AIO02103.1 - 0.018 15.0 0.0 0.029 14.3 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 AIO02103.1 - 0.03 13.4 0.0 0.055 12.5 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 AAA_lid_5 PF17865.1 AIO02104.1 - 0.024 14.7 0.1 0.078 13.1 0.1 2.0 1 0 0 1 1 1 0 Midasin AAA lid domain Katanin_con80 PF13925.6 AIO02104.1 - 0.057 13.4 0.7 1.3 9.1 0.1 2.6 2 0 0 2 2 2 0 con80 domain of Katanin Exonuc_VII_L PF02601.15 AIO02104.1 - 0.18 11.3 1.1 14 5.1 0.0 2.5 2 0 0 2 2 2 0 Exonuclease VII, large subunit RRM_1 PF00076.22 AIO02106.1 - 1e-77 255.9 4.0 1.5e-20 72.8 0.0 4.2 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP PF00658.18 AIO02106.1 - 1.5e-21 76.3 0.3 1.2e-20 73.4 0.1 2.2 2 0 0 2 2 2 1 Poly-adenylate binding protein, unique domain RRM_5 PF13893.6 AIO02106.1 - 1.4e-10 40.9 0.2 0.00025 20.6 0.0 3.3 2 1 1 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF4523 PF15023.6 AIO02106.1 - 6e-06 26.2 0.1 0.08 12.8 0.1 3.5 2 1 1 3 3 3 1 Protein of unknown function (DUF4523) RRM_3 PF08777.11 AIO02106.1 - 6.7e-05 22.9 0.8 1 9.4 0.3 4.2 4 0 0 4 4 4 1 RNA binding motif RRM_7 PF16367.5 AIO02106.1 - 0.00021 21.4 0.6 0.45 10.7 0.1 3.7 4 2 0 4 4 4 2 RNA recognition motif Nup35_RRM_2 PF14605.6 AIO02106.1 - 0.00021 21.2 0.6 1.1 9.4 0.1 4.1 4 0 0 4 4 4 1 Nup53/35/40-type RNA recognition motif RRM_8 PF11835.8 AIO02106.1 - 0.004 17.3 0.1 0.9 9.8 0.0 2.9 4 0 0 4 4 4 1 RRM-like domain SET_assoc PF11767.8 AIO02106.1 - 0.01 15.5 1.3 8.8 6.1 0.0 3.7 4 0 0 4 4 4 0 Histone lysine methyltransferase SET associated Pkinase_C PF00433.24 AIO02106.1 - 0.03 15.0 0.0 0.11 13.3 0.0 2.0 1 0 0 1 1 1 0 Protein kinase C terminal domain XS PF03468.14 AIO02106.1 - 0.2 12.0 2.0 9.3 6.6 0.2 3.2 2 1 1 3 3 3 0 XS domain bVLRF1 PF18826.1 AIO02108.1 - 3.2e-38 130.9 0.0 7.2e-38 129.8 0.0 1.6 1 1 0 1 1 1 1 bacteroidetes VLRF1 release factor acVLRF1 PF18859.1 AIO02108.1 - 0.0036 17.6 0.2 0.012 15.9 0.2 1.9 1 0 0 1 1 1 1 Actinobacteria/chloroflexi VLRF1 release factor TF_Zn_Ribbon PF08271.12 AIO02109.1 - 0.072 12.6 0.5 0.2 11.2 0.5 1.7 1 0 0 1 1 1 0 TFIIB zinc-binding DUF1664 PF07889.12 AIO02110.1 - 7.5e-05 22.8 0.3 0.00014 21.9 0.3 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF1664) Peptidase_M26_C PF07580.14 AIO02110.1 - 0.013 14.0 0.2 0.015 13.9 0.2 1.1 1 0 0 1 1 1 0 M26 IgA1-specific Metallo-endopeptidase C-terminal region Mod_r PF07200.13 AIO02110.1 - 0.041 14.0 4.2 0.058 13.5 4.2 1.2 1 0 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein CENP-Q PF13094.6 AIO02110.1 - 0.071 13.3 2.4 0.1 12.8 2.4 1.2 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit ABC_tran_CTD PF16326.5 AIO02110.1 - 0.52 10.6 4.7 1.7 8.9 0.5 2.6 2 0 0 2 2 2 0 ABC transporter C-terminal domain APG6_N PF17675.1 AIO02110.1 - 0.57 10.7 5.9 1.1 9.7 5.9 1.6 1 1 0 1 1 1 0 Apg6 coiled-coil region PRORP PF16953.5 AIO02111.1 - 5e-31 108.1 0.2 1.2e-21 77.4 0.6 2.3 2 0 0 2 2 2 2 Protein-only RNase P PPR_long PF17177.4 AIO02111.1 - 0.019 14.3 0.8 0.095 12.0 0.3 2.3 2 1 0 2 2 2 0 Pentacotripeptide-repeat region of PRORP RNase_Zc3h12a PF11977.8 AIO02111.1 - 0.053 13.3 0.0 0.9 9.3 0.0 2.4 2 0 0 2 2 2 0 Zc3h12a-like Ribonuclease NYN domain Ribosomal_L37e PF01907.19 AIO02112.1 - 4.6e-20 71.5 7.9 7.4e-20 70.9 7.9 1.3 1 0 0 1 1 1 1 Ribosomal protein L37e PseudoU_synth_2 PF00849.22 AIO02113.1 - 1.1e-24 87.3 0.1 1.9e-24 86.5 0.1 1.4 1 0 0 1 1 1 1 RNA pseudouridylate synthase ALF PF03752.13 AIO02113.1 - 0.0033 17.3 1.7 0.011 15.6 1.7 2.0 1 0 0 1 1 1 1 Short repeats of unknown function Methyltransf_23 PF13489.6 AIO02117.1 - 2.1e-05 24.5 0.0 2.6e-05 24.1 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 AIO02117.1 - 2.6e-05 24.8 0.0 0.0011 19.6 0.0 2.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 AIO02117.1 - 0.0019 18.0 0.0 0.018 14.8 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 AIO02117.1 - 0.0032 18.2 0.0 0.0071 17.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 AIO02117.1 - 0.0066 17.1 0.0 0.47 11.2 0.0 2.7 1 1 1 2 2 2 1 Methyltransferase domain Pex16 PF08610.10 AIO02117.1 - 0.0078 15.4 0.0 2.8 7.0 0.0 2.1 2 0 0 2 2 2 2 Peroxisomal membrane protein (Pex16) BT1 PF03092.16 AIO02118.1 - 5.4e-205 681.6 12.6 6.7e-205 681.3 12.6 1.0 1 0 0 1 1 1 1 BT1 family Zeta_toxin PF06414.12 AIO02119.1 - 1.4e-06 27.7 0.0 2e-06 27.2 0.0 1.2 1 0 0 1 1 1 1 Zeta toxin AAA_18 PF13238.6 AIO02119.1 - 2.6e-06 28.0 0.0 5.3e-06 27.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.6 AIO02119.1 - 5.5e-05 23.5 0.0 9.1e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 AIO02119.1 - 0.00057 20.1 0.0 0.003 17.7 0.0 1.9 2 0 0 2 2 2 1 AAA domain ATPase_2 PF01637.18 AIO02119.1 - 0.0059 16.6 0.0 0.0098 15.8 0.0 1.3 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea AAA_16 PF13191.6 AIO02119.1 - 0.013 15.9 0.0 0.027 14.8 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain AAA_14 PF13173.6 AIO02119.1 - 0.016 15.2 0.0 0.04 13.9 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 AIO02119.1 - 0.021 15.1 0.0 0.039 14.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain Rad17 PF03215.15 AIO02119.1 - 0.034 14.1 0.0 0.057 13.3 0.0 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain RNA_helicase PF00910.22 AIO02119.1 - 0.048 14.1 0.0 0.094 13.1 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_5 PF07728.14 AIO02119.1 - 0.082 12.9 0.0 0.43 10.6 0.0 2.1 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) KTI12 PF08433.10 AIO02119.1 - 0.082 12.4 0.0 0.14 11.5 0.0 1.4 1 0 0 1 1 1 0 Chromatin associated protein KTI12 AAA PF00004.29 AIO02119.1 - 0.11 13.0 0.0 0.46 10.9 0.0 1.9 1 1 1 2 2 2 0 ATPase family associated with various cellular activities (AAA) MMR_HSR1 PF01926.23 AIO02120.1 - 0.00073 19.6 0.0 0.0018 18.3 0.0 1.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase FtsK_SpoIIIE PF01580.18 AIO02120.1 - 0.1 12.0 0.0 0.19 11.1 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family Pkinase PF00069.25 AIO02122.1 - 3.2e-56 190.6 0.0 4.7e-56 190.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 AIO02122.1 - 3.4e-34 118.3 0.0 5.2e-34 117.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase PH PF00169.29 AIO02122.1 - 2.3e-10 40.9 0.0 4.7e-10 39.9 0.0 1.6 1 0 0 1 1 1 1 PH domain Kinase-like PF14531.6 AIO02122.1 - 3.8e-07 29.7 0.0 6.5e-07 29.0 0.0 1.3 1 0 0 1 1 1 1 Kinase-like PH_11 PF15413.6 AIO02122.1 - 0.0015 18.9 0.2 0.0039 17.6 0.2 1.7 1 1 0 1 1 1 1 Pleckstrin homology domain Mcp5_PH PF12814.7 AIO02122.1 - 0.033 14.3 0.0 0.066 13.3 0.0 1.4 1 0 0 1 1 1 0 Meiotic cell cortex C-terminal pleckstrin homology Haspin_kinase PF12330.8 AIO02122.1 - 0.14 11.1 0.0 0.2 10.6 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain zf-CCCH_3 PF15663.5 AIO02123.1 - 0.00033 20.8 0.8 0.0009 19.4 0.8 1.8 1 0 0 1 1 1 1 Zinc-finger containing family zf_CCCH_4 PF18345.1 AIO02123.1 - 0.0006 19.8 5.4 0.042 13.9 0.2 2.8 2 1 0 2 2 2 2 Zinc finger domain zf-CCCH PF00642.24 AIO02123.1 - 0.003 17.4 5.7 0.005 16.7 0.1 2.4 2 0 0 2 2 2 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.6 AIO02123.1 - 0.073 13.6 9.7 2.3 8.8 0.5 2.4 2 0 0 2 2 2 0 RNA-binding, Nab2-type zinc finger zf-CCCH_4 PF18044.1 AIO02123.1 - 0.42 10.5 5.7 1.6 8.6 0.2 3.1 3 0 0 3 3 3 0 CCCH-type zinc finger Torus PF16131.5 AIO02123.1 - 2.8 8.7 5.3 7.2 7.4 1.0 2.4 1 1 1 2 2 2 0 Torus domain MMR_HSR1 PF01926.23 AIO02124.1 - 8.4e-13 48.4 0.0 1.2e-11 44.6 0.0 2.2 2 0 0 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 AIO02124.1 - 6.3e-07 29.4 0.0 5.4e-06 26.4 0.0 2.2 1 1 0 1 1 1 1 RsgA GTPase AAA_22 PF13401.6 AIO02124.1 - 0.0059 16.9 0.0 0.017 15.4 0.0 1.7 2 0 0 2 2 2 1 AAA domain FeoB_N PF02421.18 AIO02124.1 - 0.021 14.3 0.0 0.049 13.2 0.0 1.5 1 0 0 1 1 1 0 Ferrous iron transport protein B Dynamin_N PF00350.23 AIO02124.1 - 0.039 14.0 0.7 3.2 7.8 0.0 2.7 2 1 1 3 3 3 0 Dynamin family Septin PF00735.18 AIO02124.1 - 0.076 12.3 0.0 0.14 11.4 0.0 1.3 1 0 0 1 1 1 0 Septin AAA_16 PF13191.6 AIO02124.1 - 0.16 12.4 0.0 0.49 10.8 0.0 1.8 2 0 0 2 2 2 0 AAA ATPase domain CEP63 PF17045.5 AIO02125.1 - 0.022 14.7 9.2 0.3 11.0 2.0 3.1 3 1 0 3 3 3 0 Centrosomal protein of 63 kDa RRN3 PF05327.11 AIO02125.1 - 0.027 13.1 0.1 0.053 12.1 0.1 1.4 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 UPF0242 PF06785.11 AIO02125.1 - 0.25 11.4 4.4 0.23 11.6 1.3 2.2 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus DUF4407 PF14362.6 AIO02125.1 - 0.3 10.4 12.1 0.099 12.0 8.7 1.8 2 1 0 2 2 2 0 Domain of unknown function (DUF4407) bZIP_2 PF07716.15 AIO02125.1 - 0.78 9.9 6.5 13 5.9 0.3 2.9 2 0 0 2 2 2 0 Basic region leucine zipper DUF3138 PF11336.8 AIO02125.1 - 1.7 7.1 4.7 2.4 6.7 4.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) DUF4201 PF13870.6 AIO02125.1 - 3.2 7.5 13.3 0.1 12.3 4.0 3.0 4 0 0 4 4 4 0 Domain of unknown function (DUF4201) Methyltransf_4 PF02390.17 AIO02126.1 - 2.5e-36 124.7 0.0 3.3e-36 124.4 0.0 1.1 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_31 PF13847.6 AIO02126.1 - 0.00078 19.3 0.0 0.0024 17.7 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 AIO02126.1 - 0.0022 18.7 0.0 0.014 16.1 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 AIO02126.1 - 0.012 16.3 0.0 0.027 15.2 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain DUF3987 PF13148.6 AIO02126.1 - 0.068 12.2 0.0 0.09 11.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) ALG11_N PF15924.5 AIO02127.1 - 2.7e-61 207.3 0.1 4.3e-61 206.6 0.1 1.3 1 0 0 1 1 1 1 ALG11 mannosyltransferase N-terminus Glycos_transf_1 PF00534.20 AIO02127.1 - 7.1e-22 77.7 0.0 1e-21 77.2 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 AIO02127.1 - 1.3e-10 41.9 0.1 2.1e-10 41.1 0.1 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 AIO02127.1 - 0.0065 16.8 0.0 0.016 15.6 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferases group 1 HALZ PF02183.18 AIO02128.1 - 2.2e-05 24.6 0.8 4e-05 23.8 0.8 1.4 1 0 0 1 1 1 1 Homeobox associated leucine zipper DivIC PF04977.15 AIO02128.1 - 0.014 15.1 0.6 0.014 15.1 0.6 1.9 2 0 0 2 2 2 0 Septum formation initiator bZIP_1 PF00170.21 AIO02128.1 - 0.03 14.4 1.7 0.083 13.0 0.1 2.0 2 0 0 2 2 2 0 bZIP transcription factor Dpy-30 PF05186.13 AIO02128.1 - 0.042 13.5 0.2 0.11 12.2 0.2 1.7 1 1 0 1 1 1 0 Dpy-30 motif WD40 PF00400.32 AIO02129.1 - 3.9e-09 37.0 7.5 0.0023 18.7 0.1 4.3 4 0 0 4 4 4 3 WD domain, G-beta repeat AD PF09793.9 AIO02131.1 - 0.049 13.8 0.0 0.087 13.0 0.0 1.3 1 0 0 1 1 1 0 Anticodon-binding domain 7tm_6 PF02949.20 AIO02132.1 - 0.069 12.2 1.0 0.12 11.4 1.0 1.3 1 0 0 1 1 1 0 7tm Odorant receptor MMR_HSR1_Xtn PF16897.5 AIO02133.1 - 2e-36 124.2 1.0 4.1e-36 123.2 1.0 1.5 1 0 0 1 1 1 1 C-terminal region of MMR_HSR1 domain TGS PF02824.21 AIO02133.1 - 8.8e-22 76.9 0.1 1.8e-21 75.9 0.1 1.6 1 0 0 1 1 1 1 TGS domain MMR_HSR1 PF01926.23 AIO02133.1 - 1.9e-18 66.6 0.0 4.4e-18 65.4 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 AIO02133.1 - 8.4e-11 41.6 0.0 1.4e-10 40.9 0.0 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.23 AIO02133.1 - 0.0058 16.7 0.3 1.5 8.8 0.0 2.4 1 1 1 2 2 2 2 Dynamin family Roc PF08477.13 AIO02133.1 - 0.02 15.1 0.1 0.74 10.1 0.0 2.8 2 2 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AIG1 PF04548.16 AIO02133.1 - 0.091 12.1 0.0 0.15 11.4 0.0 1.3 1 0 0 1 1 1 0 AIG1 family SAC3_GANP PF03399.16 AIO02134.1 - 3.5e-11 43.0 2.2 1.9e-09 37.4 2.2 2.2 1 1 0 1 1 1 1 SAC3/GANP family FMN_dh PF01070.18 AIO02135.1 - 1.6e-28 99.7 0.0 2.9e-19 69.3 0.1 2.2 2 0 0 2 2 2 2 FMN-dependent dehydrogenase IMPDH PF00478.25 AIO02135.1 - 3.7e-07 29.5 0.7 0.0053 15.8 0.1 2.3 1 1 1 2 2 2 2 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.17 AIO02135.1 - 0.00066 18.9 1.3 0.0044 16.2 1.3 2.0 1 1 0 1 1 1 1 Conserved region in glutamate synthase NMO PF03060.15 AIO02135.1 - 0.079 12.3 0.2 0.16 11.4 0.2 1.4 1 0 0 1 1 1 0 Nitronate monooxygenase DHO_dh PF01180.21 AIO02135.1 - 0.099 11.8 0.0 0.17 11.0 0.0 1.4 1 0 0 1 1 1 0 Dihydroorotate dehydrogenase His_biosynth PF00977.21 AIO02135.1 - 0.34 10.3 2.1 1.2 8.5 0.1 2.3 2 1 1 3 3 3 0 Histidine biosynthesis protein Dynein_heavy PF03028.15 AIO02136.1 - 4.3e-09 36.5 0.0 7.3e-09 35.7 0.0 1.3 1 0 0 1 1 1 1 Dynein heavy chain region D6 P-loop domain Ank_2 PF12796.7 AIO02136.1 - 1.5e-08 35.1 0.0 4.2e-08 33.7 0.0 1.7 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 AIO02136.1 - 9.3e-06 26.1 0.0 0.12 13.0 0.0 3.4 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 AIO02136.1 - 8.9e-05 22.8 0.0 0.0061 17.0 0.0 2.6 2 0 0 2 2 2 1 Ankyrin repeat Ank_3 PF13606.6 AIO02136.1 - 0.017 15.6 0.0 0.31 11.8 0.0 2.8 2 1 0 2 2 2 0 Ankyrin repeat Aa_trans PF01490.18 AIO02137.1 - 5.4e-51 173.6 32.5 6.1e-51 173.4 32.5 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein DUF3850 PF12961.7 AIO02137.1 - 0.045 13.8 0.1 0.11 12.6 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3850) Aa_trans PF01490.18 AIO02138.1 - 6.9e-50 169.9 38.2 8.7e-50 169.6 38.2 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein DAGK_acc PF00609.19 AIO02139.1 - 5.1e-40 137.4 0.0 7.3e-40 136.9 0.0 1.2 1 0 0 1 1 1 1 Diacylglycerol kinase accessory domain DAGK_cat PF00781.24 AIO02139.1 - 1.2e-13 50.7 0.0 2e-13 50.1 0.0 1.3 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain NAD_kinase PF01513.21 AIO02139.1 - 0.021 14.0 0.0 0.031 13.5 0.0 1.2 1 0 0 1 1 1 0 ATP-NAD kinase Vps16_N PF04841.13 AIO02139.1 - 0.14 10.9 0.0 0.21 10.3 0.0 1.2 1 0 0 1 1 1 0 Vps16, N-terminal region HECT PF00632.25 AIO02141.1 - 6.4e-37 127.7 0.6 2.2e-36 125.9 0.6 1.9 1 1 0 1 1 1 1 HECT-domain (ubiquitin-transferase) SPRY PF00622.28 AIO02141.1 - 4.9e-16 58.9 0.0 2.5e-07 30.8 0.0 4.8 6 0 0 6 6 6 3 SPRY domain CENP-T_C PF15511.6 AIO02142.1 - 1.1e-05 25.5 0.1 1.8e-05 24.8 0.0 1.3 1 1 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold TAF PF02969.17 AIO02142.1 - 0.00063 19.9 0.1 0.00099 19.2 0.1 1.3 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.23 AIO02142.1 - 0.00064 20.0 0.4 0.00088 19.5 0.0 1.4 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.13 AIO02142.1 - 0.0027 17.7 0.0 0.0032 17.4 0.0 1.2 1 0 0 1 1 1 1 Bromodomain associated Histone PF00125.24 AIO02142.1 - 0.0052 17.1 1.8 0.0098 16.3 1.8 1.5 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID-31kDa PF02291.15 AIO02142.1 - 0.047 13.8 0.0 0.062 13.4 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Amidohydro_1 PF01979.20 AIO02144.1 - 1.2e-09 38.0 2.7 2.3e-08 33.7 2.7 2.8 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 AIO02144.1 - 8.3e-08 32.1 0.1 0.024 14.1 0.0 2.9 3 0 0 3 3 3 2 Amidohydrolase family PUF PF00806.19 AIO02145.1 - 1.2e-31 106.6 12.9 7.7e-06 25.3 0.1 7.6 7 0 0 7 7 7 7 Pumilio-family RNA binding repeat CPL PF08144.11 AIO02145.1 - 1.1e-05 25.8 1.3 0.98 9.8 0.2 4.3 3 2 0 3 3 3 2 CPL (NUC119) domain TFIIB_C_1 PF18542.1 AIO02145.1 - 0.03 14.3 0.2 0.11 12.5 0.2 2.0 1 0 0 1 1 1 0 Transcription factor IIB C-terminal module 1 IFP_35_N PF07334.13 AIO02145.1 - 0.15 12.2 0.4 4.2 7.5 1.1 2.4 2 0 0 2 2 2 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus SAP PF02037.27 AIO02146.1 - 4.1e-12 45.6 0.1 8.4e-12 44.6 0.1 1.6 1 0 0 1 1 1 1 SAP domain NAM-associated PF14303.6 AIO02146.1 - 0.044 14.5 1.5 0.1 13.3 1.5 1.6 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain Menin PF05053.13 AIO02146.1 - 0.25 9.6 1.1 0.32 9.3 1.1 1.1 1 0 0 1 1 1 0 Menin MRI PF15325.6 AIO02146.1 - 1.3 10.2 6.6 2.1 9.5 3.2 2.5 2 0 0 2 2 2 0 Modulator of retrovirus infection TPR_1 PF00515.28 AIO02147.1 - 7.6e-38 126.8 12.7 2.2e-07 30.4 0.1 6.4 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_2 PF07719.17 AIO02147.1 - 5.9e-32 107.2 9.8 3.4e-06 26.8 0.0 6.1 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_8 PF13181.6 AIO02147.1 - 2.3e-21 74.2 8.3 0.00091 19.3 0.0 6.2 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_11 PF13414.6 AIO02147.1 - 8.8e-18 63.7 6.9 0.0012 18.5 0.0 5.8 4 2 2 6 6 6 4 TPR repeat TPR_12 PF13424.6 AIO02147.1 - 3.1e-16 59.4 3.4 0.00012 22.3 0.1 4.4 3 1 0 4 4 4 3 Tetratricopeptide repeat TPR_7 PF13176.6 AIO02147.1 - 1.8e-13 49.5 0.8 0.00049 19.9 0.0 5.3 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_16 PF13432.6 AIO02147.1 - 9.1e-13 48.6 0.9 0.012 16.3 0.0 4.3 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_14 PF13428.6 AIO02147.1 - 4.4e-12 45.7 1.0 0.024 15.4 0.0 5.1 3 1 2 5 5 5 3 Tetratricopeptide repeat TPR_17 PF13431.6 AIO02147.1 - 8.2e-11 41.5 3.3 0.09 13.2 0.1 6.4 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_6 PF13174.6 AIO02147.1 - 9e-11 41.7 3.1 0.015 15.9 0.0 5.3 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_19 PF14559.6 AIO02147.1 - 2.2e-09 37.7 0.9 0.079 13.5 0.0 3.8 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_10 PF13374.6 AIO02147.1 - 1.2e-08 34.6 3.9 0.022 14.6 0.0 4.7 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_9 PF13371.6 AIO02147.1 - 1.5e-08 34.7 0.4 0.01 15.9 0.0 3.4 4 0 0 4 4 4 2 Tetratricopeptide repeat MIT PF04212.18 AIO02147.1 - 6e-06 26.2 12.4 0.081 13.0 0.2 4.4 4 2 0 4 4 4 3 MIT (microtubule interacting and transport) domain SHNi-TPR PF10516.9 AIO02147.1 - 9.3e-06 25.0 0.6 0.083 12.4 0.0 4.5 5 0 0 5 5 5 1 SHNi-TPR DUF3856 PF12968.7 AIO02147.1 - 1.2e-05 25.4 3.4 0.049 13.7 0.3 3.3 2 1 0 2 2 2 2 Domain of Unknown Function (DUF3856) ANAPC3 PF12895.7 AIO02147.1 - 1.6e-05 25.1 2.3 0.12 12.6 0.1 3.4 2 2 1 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 Sel1 PF08238.12 AIO02147.1 - 4.2e-05 24.1 4.7 0.36 11.6 0.1 3.8 2 1 1 3 3 3 2 Sel1 repeat SPO22 PF08631.10 AIO02147.1 - 9.8e-05 22.0 0.9 0.027 14.0 0.3 2.7 3 0 0 3 3 3 1 Meiosis protein SPO22/ZIP4 like TPR_21 PF09976.9 AIO02147.1 - 0.0061 16.3 2.1 0.19 11.4 0.3 2.8 2 1 0 2 2 2 1 Tetratricopeptide repeat-like domain DUF2225 PF09986.9 AIO02147.1 - 0.044 13.5 3.4 1.1 9.0 0.2 3.2 1 1 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2225) PPR PF01535.20 AIO02147.1 - 0.056 13.7 0.8 31 5.1 0.0 4.0 4 0 0 4 4 3 0 PPR repeat DUF5375 PF17345.2 AIO02147.1 - 0.057 13.3 0.1 0.19 11.6 0.2 1.8 2 0 0 2 2 2 0 Family of unknown function (DUF5375) MAS20 PF02064.15 AIO02147.1 - 0.064 13.3 1.1 6.9 6.8 0.0 2.9 1 1 1 2 2 2 0 MAS20 protein import receptor TPR_3 PF07720.12 AIO02147.1 - 0.073 13.1 5.1 0.17 11.9 0.1 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_15 PF13429.6 AIO02147.1 - 0.097 11.9 2.3 5.5 6.1 0.0 3.4 1 1 2 4 4 4 0 Tetratricopeptide repeat LCM PF04072.14 AIO02148.1 - 2.7e-24 86.2 0.0 1.1e-23 84.2 0.0 1.8 1 1 0 1 1 1 1 Leucine carboxyl methyltransferase T6SS_TssG PF06996.11 AIO02149.1 - 0.031 13.5 0.0 0.071 12.3 0.0 1.5 1 0 0 1 1 1 0 Type VI secretion, TssG IMS PF00817.20 AIO02150.1 - 4e-33 114.5 0.0 8.9e-33 113.4 0.0 1.6 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.8 AIO02150.1 - 0.049 14.3 0.0 0.13 13.0 0.0 1.7 1 1 0 1 1 1 0 impB/mucB/samB family C-terminal domain Acetyltransf_8 PF13523.6 AIO02151.1 - 0.071 12.8 0.1 0.34 10.6 0.0 2.2 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Pox_MCEL PF03291.16 AIO02152.1 - 4.2e-34 118.1 0.0 2.8e-33 115.4 0.0 1.9 1 1 0 1 1 1 1 mRNA capping enzyme Methyltransf_23 PF13489.6 AIO02152.1 - 8.2e-05 22.5 0.0 0.00029 20.7 0.0 1.8 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 AIO02152.1 - 0.00099 19.8 0.0 0.0042 17.8 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain NNMT_PNMT_TEMT PF01234.17 AIO02152.1 - 0.0024 17.1 0.0 0.082 12.1 0.0 2.1 2 0 0 2 2 2 1 NNMT/PNMT/TEMT family Methyltransf_12 PF08242.12 AIO02152.1 - 0.023 15.5 0.0 0.091 13.5 0.0 2.1 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.6 AIO02152.1 - 0.056 13.2 0.0 0.37 10.6 0.0 2.1 1 1 0 1 1 1 0 Methyltransferase domain PUB PF09409.10 AIO02153.1 - 5.8e-17 61.4 0.0 1.8e-16 59.8 0.0 1.9 2 0 0 2 2 2 1 PUB domain Dodecin PF07311.12 AIO02153.1 - 0.021 15.0 0.5 0.064 13.5 0.1 2.0 2 0 0 2 2 2 0 Dodecin Draxin PF15550.6 AIO02153.1 - 0.19 11.6 6.4 0.27 11.1 6.4 1.3 1 0 0 1 1 1 0 Draxin DUF4706 PF15797.5 AIO02153.1 - 3.9 8.1 5.8 5.4 7.6 5.2 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4706) Borrelia_orfA PF02414.15 AIO02153.1 - 3.9 7.0 8.1 5.7 6.5 8.1 1.1 1 0 0 1 1 1 0 Borrelia ORF-A His_Phos_1 PF00300.22 AIO02155.1 - 2.7e-26 92.5 0.0 1.5e-25 90.1 0.0 2.0 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) AAA_24 PF13479.6 AIO02155.1 - 0.24 11.1 0.0 0.39 10.4 0.0 1.2 1 0 0 1 1 1 0 AAA domain GTP_EFTU PF00009.27 AIO02158.1 - 5.4e-65 218.6 0.4 8.6e-65 217.9 0.4 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 AIO02158.1 - 4.7e-29 100.6 0.0 1.3e-28 99.2 0.0 1.8 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_C PF00679.24 AIO02158.1 - 4.9e-20 71.4 0.0 1.7e-19 69.6 0.0 2.0 2 0 0 2 2 2 1 Elongation factor G C-terminus EFG_II PF14492.6 AIO02158.1 - 6.2e-14 51.9 0.0 3.1e-13 49.6 0.0 2.1 2 0 0 2 2 2 1 Elongation Factor G, domain II GTP_EFTU_D2 PF03144.25 AIO02158.1 - 6e-13 49.0 0.1 1.6e-12 47.6 0.1 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 AIO02158.1 - 0.0021 18.1 0.1 0.0052 16.9 0.1 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase Peptidase_S24 PF00717.23 AIO02159.1 - 6e-07 29.3 0.0 9.9e-07 28.6 0.0 1.3 1 0 0 1 1 1 1 Peptidase S24-like Peptidase_S26 PF10502.9 AIO02159.1 - 0.0072 16.1 0.0 0.017 14.9 0.0 1.6 1 0 0 1 1 1 1 Signal peptidase, peptidase S26 DUF5417 PF17438.2 AIO02159.1 - 0.06 13.7 0.0 0.1 12.9 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5417) SET PF00856.28 AIO02160.1 - 3.8e-09 37.2 0.1 1.8e-07 31.7 0.1 2.3 1 1 0 1 1 1 1 SET domain Glycos_transf_2 PF00535.26 AIO02161.1 - 1e-30 106.8 0.0 1.3e-30 106.5 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 AIO02161.1 - 5e-05 23.3 0.0 7.1e-05 22.8 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 DUF2606 PF10794.9 AIO02161.1 - 0.0049 16.6 0.0 0.009 15.8 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2606) FKBP_C PF00254.28 AIO02162.1 - 7.1e-28 96.8 0.0 8.9e-28 96.5 0.0 1.0 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase DUF4164 PF13747.6 AIO02163.1 - 1.6e-05 25.1 4.0 1.6e-05 25.1 4.0 2.6 2 1 1 3 3 3 1 Domain of unknown function (DUF4164) ADIP PF11559.8 AIO02163.1 - 1.9e-05 24.8 10.5 1.9e-05 24.8 10.5 1.9 2 0 0 2 2 2 1 Afadin- and alpha -actinin-Binding CENP-F_leu_zip PF10473.9 AIO02163.1 - 0.00011 22.2 13.6 0.00011 22.2 13.6 1.8 2 0 0 2 2 2 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 TPR_MLP1_2 PF07926.12 AIO02163.1 - 0.00021 21.3 19.2 0.0008 19.5 13.1 2.6 2 1 1 3 3 3 2 TPR/MLP1/MLP2-like protein CEP63 PF17045.5 AIO02163.1 - 0.0008 19.4 10.2 0.0008 19.4 10.2 1.5 2 0 0 2 2 2 1 Centrosomal protein of 63 kDa KASH_CCD PF14662.6 AIO02163.1 - 0.0025 17.6 17.0 0.0058 16.5 16.1 1.8 2 0 0 2 2 2 1 Coiled-coil region of CCDC155 or KASH Phage_GP20 PF06810.11 AIO02163.1 - 0.0038 17.0 5.3 0.0069 16.2 5.3 1.3 1 0 0 1 1 1 1 Phage minor structural protein GP20 Golgin_A5 PF09787.9 AIO02163.1 - 0.0053 16.3 10.2 0.014 14.9 8.5 1.9 2 0 0 2 2 2 1 Golgin subfamily A member 5 GldM_N PF12081.8 AIO02163.1 - 0.0069 16.5 1.8 0.012 15.7 1.8 1.3 1 0 0 1 1 1 1 GldM N-terminal domain STAT_alpha PF01017.20 AIO02163.1 - 0.015 15.2 8.4 0.028 14.3 8.4 1.5 1 0 0 1 1 1 0 STAT protein, all-alpha domain bZIP_1 PF00170.21 AIO02163.1 - 0.016 15.3 0.5 0.016 15.3 0.5 3.2 2 2 2 4 4 3 0 bZIP transcription factor Atg14 PF10186.9 AIO02163.1 - 0.019 14.0 15.4 0.015 14.4 10.2 2.3 2 1 1 3 3 3 0 Vacuolar sorting 38 and autophagy-related subunit 14 FlaC_arch PF05377.11 AIO02163.1 - 0.037 14.4 0.4 0.037 14.4 0.4 2.6 2 1 0 3 3 2 0 Flagella accessory protein C (FlaC) V_ATPase_I PF01496.19 AIO02163.1 - 0.039 11.9 1.8 0.035 12.0 1.8 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family ATG16 PF08614.11 AIO02163.1 - 0.041 14.1 18.6 0.092 13.0 12.9 2.2 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) RskA PF10099.9 AIO02163.1 - 0.056 13.7 1.5 0.078 13.3 1.5 1.2 1 0 0 1 1 1 0 Anti-sigma-K factor rskA FapA PF03961.13 AIO02163.1 - 0.056 12.0 4.7 0.081 11.5 4.7 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A YabA PF06156.13 AIO02163.1 - 0.062 13.9 13.5 1.1 9.9 3.9 2.6 2 1 1 3 3 2 0 Initiation control protein YabA DUF1664 PF07889.12 AIO02163.1 - 0.069 13.2 4.3 0.14 12.2 4.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Seryl_tRNA_N PF02403.22 AIO02163.1 - 0.078 13.2 12.9 0.03 14.6 8.4 2.1 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Spectrin PF00435.21 AIO02163.1 - 0.099 13.1 10.3 0.041 14.4 5.9 2.3 2 1 0 2 2 2 0 Spectrin repeat Spc7 PF08317.11 AIO02163.1 - 0.11 11.4 13.5 0.061 12.2 11.1 1.6 2 0 0 2 2 2 0 Spc7 kinetochore protein COG5 PF10392.9 AIO02163.1 - 0.19 11.9 5.4 0.057 13.6 2.7 1.5 2 0 0 2 2 1 0 Golgi transport complex subunit 5 HemX PF04375.14 AIO02163.1 - 0.2 10.9 9.8 0.022 14.1 4.8 1.7 2 0 0 2 2 2 0 HemX, putative uroporphyrinogen-III C-methyltransferase DUF4250 PF14056.6 AIO02163.1 - 0.28 11.2 2.0 7.2 6.6 0.2 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4250) HAUS-augmin3 PF14932.6 AIO02163.1 - 0.41 10.2 12.0 0.094 12.3 8.2 1.8 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 3 Sec34 PF04136.15 AIO02163.1 - 0.47 10.3 8.6 0.37 10.7 4.9 2.4 2 1 1 3 3 3 0 Sec34-like family AKNA PF12443.8 AIO02163.1 - 0.64 10.7 8.8 0.41 11.3 4.6 2.6 2 1 0 2 2 2 0 AT-hook-containing transcription factor FliJ PF02050.16 AIO02163.1 - 0.73 10.1 16.2 0.076 13.2 8.8 2.3 2 0 0 2 2 2 0 Flagellar FliJ protein APG6_N PF17675.1 AIO02163.1 - 0.79 10.3 20.4 3.6 8.1 16.0 2.7 2 1 0 2 2 2 0 Apg6 coiled-coil region ZapB PF06005.12 AIO02163.1 - 0.89 10.0 21.7 1.3 9.5 10.2 3.4 2 1 1 3 3 3 0 Cell division protein ZapB UPF0242 PF06785.11 AIO02163.1 - 0.98 9.5 9.9 0.85 9.7 8.1 1.7 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Nup88 PF10168.9 AIO02163.1 - 1.2 6.9 10.3 1.6 6.5 10.3 1.1 1 0 0 1 1 1 0 Nuclear pore component SOGA PF11365.8 AIO02163.1 - 1.2 10.3 15.1 0.51 11.5 11.5 2.1 2 1 0 2 2 1 0 Protein SOGA DUF4446 PF14584.6 AIO02163.1 - 1.4 8.9 5.3 0.22 11.5 1.4 1.7 2 1 0 2 2 1 0 Protein of unknown function (DUF4446) DASH_Spc34 PF08657.10 AIO02163.1 - 1.4 8.7 7.5 0.74 9.6 4.2 1.8 2 0 0 2 2 2 0 DASH complex subunit Spc34 CENP-H PF05837.12 AIO02163.1 - 1.6 9.2 14.1 1.3 9.4 9.1 2.3 2 0 0 2 2 2 0 Centromere protein H (CENP-H) Swi5 PF07061.11 AIO02163.1 - 1.6 8.9 8.8 1.7 8.7 4.7 2.7 2 1 0 2 2 2 0 Swi5 COG2 PF06148.11 AIO02163.1 - 1.7 8.8 9.0 0.67 10.0 6.4 1.8 2 0 0 2 2 1 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF2968 PF11180.8 AIO02163.1 - 2 8.0 19.6 0.2 11.3 11.7 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2968) Jnk-SapK_ap_N PF09744.9 AIO02163.1 - 3.2 8.0 18.3 3.9 7.7 13.9 2.4 2 1 0 2 2 2 0 JNK_SAPK-associated protein-1 YlqD PF11068.8 AIO02163.1 - 3.2 8.1 13.2 1.8 9.0 10.0 1.9 2 0 0 2 2 2 0 YlqD protein ApoO PF09769.9 AIO02163.1 - 3.5 7.6 5.6 0.41 10.6 0.6 1.8 2 0 0 2 2 2 0 Apolipoprotein O PRKG1_interact PF15898.5 AIO02163.1 - 4.2 8.3 17.9 2 9.4 13.4 2.0 2 0 0 2 2 2 0 cGMP-dependent protein kinase interacting domain DivIC PF04977.15 AIO02163.1 - 4.2 7.2 17.2 0.22 11.3 4.8 3.3 2 1 1 3 3 3 0 Septum formation initiator Fungal_TACC PF12709.7 AIO02163.1 - 4.9 7.7 11.0 1.1 9.8 2.5 2.8 2 1 0 3 3 2 0 Fungal Transforming acidic coiled-coil (TACC) proteins GAS PF13851.6 AIO02163.1 - 5.8 6.2 17.9 4.5 6.6 14.7 2.1 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding DinB PF05163.12 AIO02163.1 - 6.8 6.6 8.9 17 5.3 0.3 2.9 2 1 1 3 3 3 0 DinB family TMPIT PF07851.13 AIO02163.1 - 7.4 5.7 11.7 0.66 9.2 7.3 1.4 2 0 0 2 2 1 0 TMPIT-like protein DUF3450 PF11932.8 AIO02163.1 - 9.1 5.5 17.1 0.12 11.7 3.7 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF3450) DUF883 PF05957.13 AIO02163.1 - 9.8 6.9 10.5 15 6.3 6.4 2.5 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF883) Paf67 PF10255.9 AIO02164.1 - 1.7e-49 168.9 0.0 3.7e-49 167.8 0.0 1.5 1 1 0 1 1 1 1 RNA polymerase I-associated factor PAF67 TPR_2 PF07719.17 AIO02164.1 - 0.094 12.9 0.0 1.4 9.2 0.0 2.7 3 0 0 3 3 3 0 Tetratricopeptide repeat FGGY_N PF00370.21 AIO02165.1 - 3e-12 46.7 0.0 3.7e-12 46.3 0.0 1.0 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain CH PF00307.31 AIO02166.1 - 0.00052 20.2 0.0 0.88 9.8 0.0 3.0 3 0 0 3 3 3 2 Calponin homology (CH) domain TFIIS_M PF07500.14 AIO02167.1 - 4.3e-06 27.2 0.2 7.9e-06 26.3 0.2 1.4 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS), central domain NUDIX PF00293.28 AIO02169.1 - 2.7e-14 53.3 0.0 3.8e-14 52.8 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain ESCRT-II PF05871.12 AIO02170.1 - 1.9e-12 47.6 0.0 1e-11 45.3 0.0 1.9 1 1 0 1 1 1 1 ESCRT-II complex subunit DUF3223 PF11523.8 AIO02170.1 - 0.071 14.0 0.4 4.3 8.3 0.0 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF3223) Proteasome PF00227.26 AIO02171.1 - 1.6e-29 102.7 0.0 2e-29 102.5 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit RNase_HII PF01351.18 AIO02172.1 - 1.7e-18 67.1 0.0 4.4e-10 39.7 0.0 2.3 2 0 0 2 2 2 2 Ribonuclease HII Nop10p PF04135.12 AIO02173.1 - 3.1e-21 75.1 0.5 4e-21 74.8 0.5 1.1 1 0 0 1 1 1 1 Nucleolar RNA-binding protein, Nop10p family IQ PF00612.27 AIO02174.1 - 0.016 15.0 2.4 0.082 12.7 2.4 2.2 1 0 0 1 1 1 0 IQ calmodulin-binding motif EMC3_TMCO1 PF01956.16 AIO02175.1 - 5.2e-47 159.7 2.6 7.1e-47 159.3 2.6 1.2 1 0 0 1 1 1 1 Integral membrane protein EMC3/TMCO1-like PIP5K PF01504.18 AIO02176.1 - 6.9e-62 209.2 0.0 1.2e-61 208.4 0.0 1.4 1 1 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase Spore_coat_CotO PF14153.6 AIO02177.1 - 0.0065 16.4 1.7 0.0077 16.2 1.7 1.1 1 0 0 1 1 1 1 Spore coat protein CotO Med3 PF11593.8 AIO02178.1 - 0.00017 20.9 10.6 0.00017 20.9 10.6 2.1 2 0 0 2 2 2 1 Mediator complex subunit 3 fungal DB_JBP1 PF18526.1 AIO02178.1 - 0.0038 17.2 0.0 0.0074 16.2 0.0 1.5 1 0 0 1 1 1 1 Thymine dioxygenase JBP1 DNA-binding domain Macoilin PF09726.9 AIO02178.1 - 0.05 12.2 9.3 0.067 11.7 9.3 1.1 1 0 0 1 1 1 0 Macoilin family Spore_coat_CotO PF14153.6 AIO02178.1 - 0.12 12.3 4.2 0.22 11.4 4.2 1.4 1 0 0 1 1 1 0 Spore coat protein CotO Pex14_N PF04695.13 AIO02178.1 - 1.1 9.9 16.3 4.1 8.0 16.3 2.0 1 1 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region SPX PF03105.19 AIO02178.1 - 1.7 8.5 17.1 2.5 8.0 17.1 1.2 1 0 0 1 1 1 0 SPX domain DUF4614 PF15391.6 AIO02178.1 - 6.2 6.8 18.1 12 5.9 18.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) Ndc1_Nup PF09531.10 AIO02178.1 - 6.6 5.3 13.2 9.4 4.8 13.2 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Peptidase_S64 PF08192.11 AIO02178.1 - 7.1 5.0 9.9 8.7 4.7 9.9 1.1 1 0 0 1 1 1 0 Peptidase family S64 Apt1 PF10351.9 AIO02178.1 - 9.5 5.0 14.7 15 4.3 14.7 1.3 1 0 0 1 1 1 0 Golgi-body localisation protein domain PDZ_2 PF13180.6 AIO02179.1 - 0.00013 22.3 0.1 0.00032 21.0 0.1 1.7 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 AIO02179.1 - 0.015 15.6 0.1 0.04 14.3 0.1 1.7 1 0 0 1 1 1 0 PDZ domain GSCFA PF08885.11 AIO02179.1 - 0.074 12.7 1.0 0.46 10.1 0.2 2.1 1 1 0 2 2 2 0 GSCFA family Collagen_mid PF15984.5 AIO02179.1 - 0.25 11.0 6.5 0.16 11.7 2.0 2.4 2 1 1 3 3 3 0 Bacterial collagen, middle region Tmp39 PF10271.9 AIO02179.1 - 0.36 9.8 1.5 0.51 9.3 1.5 1.1 1 0 0 1 1 1 0 Putative transmembrane protein YgaB PF14182.6 AIO02179.1 - 0.88 10.0 6.9 0.41 11.1 1.6 2.7 2 1 1 3 3 3 0 YgaB-like protein DUF1664 PF07889.12 AIO02179.1 - 5.1 7.2 7.9 22 5.1 4.4 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) ArnB_C PF18677.1 AIO02180.1 - 0.018 15.2 3.3 0.032 14.3 3.3 1.5 1 0 0 1 1 1 0 Archaellum regulatory network B, C-terminal domain HrpB1_HrpK PF09613.10 AIO02180.1 - 0.065 12.9 0.1 0.13 11.9 0.1 1.6 1 0 0 1 1 1 0 Bacterial type III secretion protein (HrpB1_HrpK) MIF PF01187.18 AIO02180.1 - 0.086 13.1 0.1 0.24 11.7 0.0 1.8 2 0 0 2 2 2 0 Macrophage migration inhibitory factor (MIF) Aa_trans PF01490.18 AIO02181.1 - 8.4e-61 205.9 23.8 9.7e-61 205.7 23.8 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 AIO02181.1 - 6.6e-09 35.3 15.9 6.6e-09 35.3 15.9 1.8 2 0 0 2 2 2 1 Tryptophan/tyrosine permease family TFIIA_gamma_C PF02751.14 AIO02182.1 - 0.00057 20.0 0.0 0.00092 19.3 0.0 1.2 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit W2 PF02020.18 AIO02183.1 - 0.046 13.9 0.2 1.2 9.3 0.0 2.6 2 0 0 2 2 2 0 eIF4-gamma/eIF5/eIF2-epsilon Sec1 PF00995.23 AIO02185.1 - 5.7e-101 339.5 0.4 7.1e-101 339.2 0.4 1.1 1 0 0 1 1 1 1 Sec1 family Ppx-GppA PF02541.16 AIO02185.1 - 0.1 12.0 0.2 0.35 10.3 0.1 1.8 2 0 0 2 2 2 0 Ppx/GppA phosphatase family Dus PF01207.17 AIO02186.1 - 4.7e-36 124.5 0.2 1.2e-31 110.0 0.0 2.3 2 0 0 2 2 2 2 Dihydrouridine synthase (Dus) zf-ANAPC11 PF12861.7 AIO02187.1 - 0.021 14.9 0.8 0.039 14.0 0.8 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C2HC_2 PF13913.6 AIO02188.1 - 2.1e-16 59.4 6.3 9.4e-10 38.1 1.3 2.3 2 0 0 2 2 2 2 zinc-finger of a C2HC-type zf-H2C2_2 PF13465.6 AIO02188.1 - 0.095 13.2 0.2 13 6.4 0.1 2.3 2 0 0 2 2 2 0 Zinc-finger double domain FAM76 PF16046.5 AIO02188.1 - 0.19 11.1 0.3 0.28 10.5 0.3 1.2 1 0 0 1 1 1 0 FAM76 protein zf-C2H2_4 PF13894.6 AIO02188.1 - 0.21 12.5 3.3 20 6.4 1.5 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2_6 PF13912.6 AIO02188.1 - 0.25 11.4 3.5 3 7.9 0.2 2.6 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2 PF00096.26 AIO02188.1 - 0.26 11.8 2.7 15 6.3 1.3 2.5 2 0 0 2 2 2 0 Zinc finger, C2H2 type Sgf11 PF08209.11 AIO02188.1 - 0.27 10.8 3.2 6.5 6.4 1.1 2.4 2 0 0 2 2 2 0 Sgf11 (transcriptional regulation protein) ADK_lid PF05191.14 AIO02188.1 - 0.49 10.4 3.7 2.3 8.3 0.5 2.3 2 0 0 2 2 2 0 Adenylate kinase, active site lid DnaJ PF00226.31 AIO02189.1 - 2.1e-20 72.6 1.6 5.1e-20 71.4 0.3 2.3 2 0 0 2 2 2 1 DnaJ domain TPR_2 PF07719.17 AIO02189.1 - 3.6e-14 51.6 31.6 0.0001 22.1 0.1 7.9 8 1 0 8 8 8 4 Tetratricopeptide repeat TPR_19 PF14559.6 AIO02189.1 - 1.2e-11 44.9 19.4 0.0027 18.2 2.0 6.0 5 2 2 7 7 7 5 Tetratricopeptide repeat TPR_9 PF13371.6 AIO02189.1 - 2.4e-09 37.2 9.6 0.0013 18.8 0.2 4.7 3 1 0 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.28 AIO02189.1 - 5.2e-09 35.6 29.3 0.0014 18.4 0.6 7.2 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_14 PF13428.6 AIO02189.1 - 2.2e-08 34.2 26.5 0.022 15.6 0.1 8.1 6 1 2 8 8 8 3 Tetratricopeptide repeat TPR_16 PF13432.6 AIO02189.1 - 1.7e-05 25.3 7.9 0.00015 22.3 3.4 6.5 4 2 3 7 7 7 4 Tetratricopeptide repeat TPR_11 PF13414.6 AIO02189.1 - 3e-05 23.6 8.2 0.0017 18.0 1.5 5.2 5 2 1 6 6 6 3 TPR repeat TPR_12 PF13424.6 AIO02189.1 - 0.00012 22.3 20.6 0.002 18.4 1.8 5.7 3 2 3 6 6 6 1 Tetratricopeptide repeat TPR_8 PF13181.6 AIO02189.1 - 0.0003 20.8 24.1 0.26 11.6 0.2 6.5 8 0 0 8 8 7 2 Tetratricopeptide repeat TPR_17 PF13431.6 AIO02189.1 - 0.0021 18.3 0.5 0.0021 18.3 0.5 6.4 7 0 0 7 7 6 1 Tetratricopeptide repeat TPR_10 PF13374.6 AIO02189.1 - 0.0025 17.6 0.4 0.0025 17.6 0.4 5.6 6 0 0 6 6 6 1 Tetratricopeptide repeat ANAPC3 PF12895.7 AIO02189.1 - 0.0074 16.5 0.4 0.0074 16.5 0.4 4.2 2 2 1 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.6 AIO02189.1 - 0.027 14.5 10.5 8.1 6.7 0.2 5.3 5 0 0 5 5 5 0 Tetratricopeptide repeat DUF5385 PF17359.2 AIO02189.1 - 0.085 12.4 3.8 0.61 9.6 0.1 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5385) Fis1_TPR_C PF14853.6 AIO02189.1 - 0.56 10.3 6.0 1.1 9.3 0.3 3.7 4 0 0 4 4 4 0 Fis1 C-terminal tetratricopeptide repeat DUF2408 PF10303.9 AIO02189.1 - 2.7 8.6 6.6 5.5 7.6 1.3 2.7 2 1 1 3 3 2 0 Protein of unknown function (DUF2408) Mito_carr PF00153.27 AIO02190.1 - 5.7e-88 289.0 18.6 1.2e-20 73.2 0.2 6.2 5 1 1 6 6 6 6 Mitochondrial carrier protein Serine_protease PF18405.1 AIO02190.1 - 0.00031 20.0 3.9 1.4 8.0 0.0 4.2 5 0 0 5 5 5 3 Gammaproteobacterial serine protease PP2C PF00481.21 AIO02192.1 - 1.3e-68 231.5 0.5 1.6e-68 231.2 0.5 1.0 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 AIO02192.1 - 0.0029 17.3 0.1 0.0048 16.6 0.1 1.5 1 1 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.12 AIO02192.1 - 0.021 14.8 0.1 0.9 9.4 0.0 2.3 2 1 0 2 2 2 0 Stage II sporulation protein E (SpoIIE) LSM PF01423.22 AIO02193.1 - 6.2e-07 29.0 0.2 9.4e-07 28.4 0.2 1.3 1 0 0 1 1 1 1 LSM domain DUF5623 PF18536.1 AIO02194.1 - 0.0093 16.2 0.0 0.018 15.3 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF5623) ubiquitin PF00240.23 AIO02195.1 - 6.4e-16 57.9 0.1 1.1e-15 57.1 0.1 1.4 1 0 0 1 1 1 1 Ubiquitin family UBA PF00627.31 AIO02195.1 - 4.4e-06 26.5 0.8 1.2e-05 25.1 0.8 1.9 1 0 0 1 1 1 1 UBA/TS-N domain Rad60-SLD PF11976.8 AIO02195.1 - 3.1e-05 23.7 0.1 5.4e-05 22.9 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 AIO02195.1 - 0.0085 16.5 0.2 0.024 15.1 0.0 1.9 2 1 0 2 2 2 1 Ubiquitin-like domain ComX PF05952.12 AIO02195.1 - 0.02 14.8 3.6 0.03 14.3 2.2 2.1 2 0 0 2 2 2 0 Bacillus competence pheromone ComX Ubiquitin_5 PF18037.1 AIO02195.1 - 0.044 14.1 0.2 0.092 13.1 0.2 1.4 1 0 0 1 1 1 0 Ubiquitin-like domain XPC-binding PF09280.11 AIO02195.1 - 0.055 13.2 16.5 0.21 11.3 16.5 2.0 1 0 0 1 1 1 0 XPC-binding domain Rad60-SLD_2 PF13881.6 AIO02195.1 - 0.079 13.1 0.2 0.21 11.7 0.2 1.7 1 1 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 AIO02195.1 - 0.089 13.4 0.0 0.16 12.5 0.0 1.5 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain RPN13_C PF16550.5 AIO02195.1 - 0.1 12.8 9.7 0.37 11.0 1.4 2.7 3 0 0 3 3 3 0 UCH-binding domain HOIP-UBA PF16678.5 AIO02195.1 - 0.19 11.7 0.9 0.34 10.9 0.1 1.8 2 0 0 2 2 2 0 HOIP UBA domain pair GerD PF17898.1 AIO02195.1 - 7.9 6.5 17.9 11 6.0 16.2 2.1 2 1 0 2 2 2 0 Spore germination GerD central core domain Pkinase PF00069.25 AIO02196.1 - 6.2e-79 265.1 0.0 7.1e-79 264.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 AIO02196.1 - 4.8e-36 124.4 0.0 1.1e-35 123.1 0.0 1.4 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.23 AIO02196.1 - 0.0024 17.8 0.7 0.069 13.1 0.0 2.6 2 1 1 3 3 3 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 AIO02196.1 - 0.0062 15.5 0.0 0.034 13.1 0.0 1.9 1 1 0 1 1 1 1 Haspin like kinase domain YabA PF06156.13 AIO02197.1 - 0.93 10.2 18.3 0.82 10.3 2.8 3.7 2 1 1 3 3 3 0 Initiation control protein YabA Sec20 PF03908.13 AIO02197.1 - 5 7.1 8.9 1.1 9.2 0.5 3.2 2 1 0 3 3 3 0 Sec20 GTP_EFTU PF00009.27 AIO02198.1 - 4.8e-62 209.0 0.0 7.6e-62 208.3 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_II PF14492.6 AIO02198.1 - 8.1e-24 83.5 0.0 1.9e-23 82.3 0.0 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_C PF00679.24 AIO02198.1 - 6.1e-21 74.3 0.1 1.4e-20 73.1 0.1 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_IV PF03764.18 AIO02198.1 - 3.4e-18 65.6 0.0 8.3e-18 64.3 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G, domain IV GTP_EFTU_D2 PF03144.25 AIO02198.1 - 2.6e-07 30.9 0.0 8.7e-07 29.2 0.0 1.9 1 0 0 1 1 1 1 Elongation factor Tu domain 2 RF3_C PF16658.5 AIO02198.1 - 1.9e-05 24.5 0.0 7.7e-05 22.5 0.0 2.0 1 0 0 1 1 1 1 Class II release factor RF3, C-terminal domain MMR_HSR1 PF01926.23 AIO02198.1 - 0.0028 17.7 0.0 0.0061 16.6 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase DUF4132 PF13569.6 AIO02198.1 - 0.0065 16.3 0.0 0.014 15.2 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4132) AIG1 PF04548.16 AIO02198.1 - 0.036 13.4 0.0 0.073 12.4 0.0 1.4 1 0 0 1 1 1 0 AIG1 family DUF442 PF04273.13 AIO02198.1 - 0.051 13.7 0.0 0.82 9.8 0.0 2.4 2 0 0 2 2 2 0 Putative phosphatase (DUF442) DUF148 PF02520.17 AIO02198.1 - 0.12 12.5 0.2 0.27 11.4 0.2 1.5 1 0 0 1 1 1 0 Domain of unknown function DUF148 IF4E PF01652.18 AIO02199.1 - 2.6e-09 37.1 0.0 3.1e-09 36.8 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E Ribosomal_S27 PF01599.19 AIO02200.1 - 1e-22 80.0 4.2 1.9e-22 79.2 4.2 1.4 1 0 0 1 1 1 1 Ribosomal protein S27a ubiquitin PF00240.23 AIO02200.1 - 3.2e-09 36.4 0.2 3.5e-08 33.1 0.0 2.4 2 1 0 2 2 2 1 Ubiquitin family Rad60-SLD PF11976.8 AIO02200.1 - 3.4e-05 23.6 0.4 0.00056 19.7 0.0 2.4 2 1 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like IBR PF01485.21 AIO02200.1 - 0.0068 16.6 0.7 0.011 15.9 0.7 1.4 1 0 0 1 1 1 1 IBR domain, a half RING-finger domain DnaJ PF00226.31 AIO02201.1 - 1.1e-21 76.7 0.4 1.1e-21 76.7 0.4 1.6 2 0 0 2 2 2 1 DnaJ domain ATP-synt_Eps PF04627.13 AIO02202.1 - 1.2e-06 28.4 0.1 3e-06 27.1 0.1 1.6 1 1 0 1 1 1 1 Mitochondrial ATP synthase epsilon chain DUF3592 PF12158.8 AIO02203.1 - 2.9e-20 72.8 0.6 3.3e-20 72.7 0.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3592) RNase_HII PF01351.18 AIO02204.1 - 2.2e-40 138.6 0.0 2.7e-40 138.3 0.0 1.1 1 0 0 1 1 1 1 Ribonuclease HII PIG-U PF06728.13 AIO02205.1 - 2.4e-07 30.2 19.3 2e-05 23.8 19.3 2.5 1 1 0 1 1 1 1 GPI transamidase subunit PIG-U EamA PF00892.20 AIO02207.1 - 7.9e-08 32.6 27.3 1.1e-05 25.6 0.9 3.9 4 1 0 4 4 4 3 EamA-like transporter family UAA PF08449.11 AIO02207.1 - 5e-07 29.2 12.4 0.00011 21.5 0.1 2.4 3 0 0 3 3 3 2 UAA transporter family SLC35F PF06027.12 AIO02207.1 - 9.5e-06 25.3 0.2 9.5e-06 25.3 0.2 2.4 3 0 0 3 3 3 2 Solute carrier family 35 CRT-like PF08627.10 AIO02207.1 - 0.0022 17.0 12.5 0.015 14.3 12.5 2.0 1 1 0 1 1 1 1 CRT-like, chloroquine-resistance transporter-like SSB PF00436.25 AIO02210.1 - 1.7e-05 24.8 0.1 2.5e-05 24.3 0.1 1.3 1 0 0 1 1 1 1 Single-strand binding protein family LRR_9 PF14580.6 AIO02211.1 - 6.8e-14 51.7 0.1 3.3e-13 49.5 0.1 2.1 1 1 1 2 2 2 2 Leucine-rich repeat LRR_4 PF12799.7 AIO02211.1 - 3.6e-08 33.6 0.1 0.021 15.3 0.0 3.1 3 0 0 3 3 3 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 AIO02211.1 - 1e-07 31.6 0.2 1.6e-06 27.7 0.2 2.6 1 1 0 2 2 2 1 Leucine rich repeat Pkinase PF00069.25 AIO02212.1 - 1.3e-70 237.7 0.0 1.7e-70 237.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 AIO02212.1 - 4.5e-35 121.2 0.0 6.3e-35 120.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 AIO02212.1 - 0.00012 21.5 0.0 0.0002 20.8 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 AIO02212.1 - 0.00022 20.7 2.2 0.00041 19.8 2.2 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 AIO02212.1 - 0.0088 15.0 2.2 0.024 13.6 2.2 1.7 1 1 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 AIO02212.1 - 0.029 14.3 0.6 0.083 12.8 0.0 1.9 2 0 0 2 2 2 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 AIO02212.1 - 0.041 12.7 1.7 0.06 12.1 0.0 1.9 2 0 0 2 2 2 0 Fungal protein kinase FeoB_N PF02421.18 AIO02212.1 - 0.091 12.3 0.3 0.19 11.3 0.3 1.5 1 1 0 1 1 1 0 Ferrous iron transport protein B Torus PF16131.5 AIO02213.1 - 1.3e-06 29.0 6.6 0.00041 21.0 0.2 3.2 3 0 0 3 3 3 2 Torus domain zf-CCCH_4 PF18044.1 AIO02213.1 - 0.0039 17.0 2.8 0.0039 17.0 2.8 3.9 4 0 0 4 4 4 2 CCCH-type zinc finger zf-CCCH PF00642.24 AIO02213.1 - 0.071 13.0 0.5 0.071 13.0 0.5 4.0 4 0 0 4 4 4 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) NTPase_P4 PF11602.8 AIO02213.1 - 0.082 12.1 0.3 0.13 11.5 0.3 1.2 1 0 0 1 1 1 0 ATPase P4 of dsRNA bacteriophage phi-12 Torus PF16131.5 AIO02214.1 - 2.3e-07 31.5 3.9 0.00016 22.3 0.1 3.4 3 0 0 3 3 3 2 Torus domain zf-CCCH_4 PF18044.1 AIO02214.1 - 0.0012 18.6 1.8 0.0026 17.5 1.8 1.6 1 0 0 1 1 1 1 CCCH-type zinc finger zf_CCCH_4 PF18345.1 AIO02214.1 - 0.0075 16.3 1.2 0.0075 16.3 1.2 2.4 2 0 0 2 2 2 1 Zinc finger domain zf-CCCH PF00642.24 AIO02214.1 - 1.4 8.9 5.1 0.44 10.5 1.1 2.1 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) XPC-binding PF09280.11 AIO02215.1 - 5.1e-06 26.1 1.0 7.6e-06 25.6 0.0 1.9 2 0 0 2 2 2 1 XPC-binding domain Plasmid_RAQPRD PF09686.10 AIO02215.1 - 0.024 14.8 0.1 0.08 13.2 0.1 1.9 1 0 0 1 1 1 0 Plasmid protein of unknown function (Plasmid_RAQPRD) TPR_1 PF00515.28 AIO02216.1 - 5.4e-13 48.2 0.4 0.0022 17.8 0.0 6.0 6 0 0 6 6 6 3 Tetratricopeptide repeat DnaJ PF00226.31 AIO02216.1 - 1.6e-09 37.8 0.0 3.9e-09 36.5 0.0 1.6 1 0 0 1 1 1 1 DnaJ domain TPR_2 PF07719.17 AIO02216.1 - 4.7e-08 32.5 28.5 0.065 13.4 0.0 7.7 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_11 PF13414.6 AIO02216.1 - 3.6e-07 29.7 2.7 0.048 13.4 0.2 4.5 4 0 0 4 4 4 2 TPR repeat TPR_7 PF13176.6 AIO02216.1 - 0.00023 21.0 5.0 0.72 10.0 0.1 4.4 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.6 AIO02216.1 - 0.0003 20.8 5.3 3.4 8.1 0.0 5.4 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_9 PF13371.6 AIO02216.1 - 0.0039 17.3 33.6 0.43 10.8 0.7 6.2 5 1 1 6 6 6 4 Tetratricopeptide repeat TPR_17 PF13431.6 AIO02216.1 - 0.017 15.5 2.5 18 6.0 0.1 4.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.6 AIO02216.1 - 0.02 15.2 3.2 0.02 15.2 3.2 4.8 5 1 1 6 6 5 0 Tetratricopeptide repeat TPR_14 PF13428.6 AIO02216.1 - 0.97 10.4 38.5 0.34 11.9 0.6 7.5 6 1 1 7 7 7 0 Tetratricopeptide repeat TPR_16 PF13432.6 AIO02216.1 - 1 10.1 46.0 1.4 9.6 9.5 6.2 5 1 2 7 7 6 0 Tetratricopeptide repeat Peptidase_C2 PF00648.21 AIO02218.1 - 4.1e-22 78.6 0.0 6.1e-22 78.0 0.0 1.2 1 0 0 1 1 1 1 Calpain family cysteine protease MEDS PF14417.6 AIO02218.1 - 0.38 10.6 3.9 2.4 8.0 0.1 3.1 3 0 0 3 3 3 0 MEDS: MEthanogen/methylotroph, DcmR Sensory domain PRIMA1 PF16101.5 AIO02218.1 - 1.8 8.6 5.2 4.3 7.4 1.1 2.7 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 Tfb2 PF03849.14 AIO02220.1 - 1.6e-22 80.0 0.0 2.2e-22 79.5 0.0 1.1 1 0 0 1 1 1 1 Transcription factor Tfb2 Helicase_C_3 PF13625.6 AIO02220.1 - 1.7e-06 28.2 0.3 6.9e-06 26.2 0.0 2.2 3 0 0 3 3 3 1 Helicase conserved C-terminal domain Tfb2_C PF18307.1 AIO02220.1 - 0.12 12.8 0.4 0.69 10.4 0.2 2.2 2 0 0 2 2 2 0 Transcription factor Tfb2 (p52) C-terminal domain rOmpB PF12334.8 AIO02221.1 - 0.076 12.5 0.0 0.13 11.7 0.0 1.2 1 0 0 1 1 1 0 Rickettsia outer membrane protein B Arf PF00025.21 AIO02222.1 - 6.7e-31 107.1 0.0 9.3e-31 106.6 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.22 AIO02222.1 - 6.7e-09 35.5 0.0 1.1e-08 34.8 0.0 1.3 1 0 0 1 1 1 1 Ras family Roc PF08477.13 AIO02222.1 - 2.3e-08 34.3 0.0 4.1e-08 33.5 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 AIO02222.1 - 4.7e-08 32.7 0.0 7.2e-08 32.1 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 AIO02222.1 - 4.5e-07 29.4 0.0 2.8e-06 26.8 0.0 2.0 1 1 1 2 2 2 1 G-protein alpha subunit GTP_EFTU PF00009.27 AIO02222.1 - 0.0041 16.7 0.0 0.0076 15.8 0.0 1.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain cNMP_binding PF00027.29 AIO02223.1 - 2.9e-17 62.5 1.9 6.7e-10 38.9 0.1 5.6 7 0 0 7 7 7 2 Cyclic nucleotide-binding domain C2 PF00168.30 AIO02223.1 - 1.1e-07 32.1 0.0 0.0032 17.7 0.0 4.7 5 0 0 5 5 5 2 C2 domain Torus PF16131.5 AIO02224.1 - 1.8e-06 28.6 4.7 0.00044 20.9 0.1 2.8 3 0 0 3 3 3 2 Torus domain zf_CCCH_4 PF18345.1 AIO02224.1 - 6.9 6.9 14.1 0.21 11.7 0.8 3.2 3 0 0 3 3 3 0 Zinc finger domain LUC7 PF03194.15 AIO02225.1 - 0.065 12.9 1.2 0.098 12.3 1.2 1.2 1 0 0 1 1 1 0 LUC7 N_terminus DUF4407 PF14362.6 AIO02225.1 - 0.1 11.9 11.4 0.19 11.1 11.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DivIC PF04977.15 AIO02225.1 - 0.12 12.2 8.1 0.11 12.3 1.4 2.4 2 0 0 2 2 2 0 Septum formation initiator ABC_tran_CTD PF16326.5 AIO02225.1 - 0.13 12.5 6.3 0.031 14.5 1.8 2.2 2 0 0 2 2 2 0 ABC transporter C-terminal domain TMF_DNA_bd PF12329.8 AIO02225.1 - 0.26 11.3 7.2 2.3 8.3 2.3 2.5 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding WDCP PF15390.6 AIO02225.1 - 0.82 8.0 7.6 1.2 7.4 7.6 1.2 1 0 0 1 1 1 0 WD repeat and coiled-coil-containing protein family ATG16 PF08614.11 AIO02225.1 - 1.4 9.1 24.1 0.93 9.7 9.5 2.5 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) ZapB PF06005.12 AIO02225.1 - 2.8 8.4 8.9 3.1 8.3 1.0 2.4 2 0 0 2 2 2 0 Cell division protein ZapB Exonuc_VII_L PF02601.15 AIO02225.1 - 3 7.3 9.4 4.9 6.6 9.4 1.4 1 0 0 1 1 1 0 Exonuclease VII, large subunit CASP_C PF08172.12 AIO02225.1 - 3.6 6.8 9.9 6.7 6.0 9.9 1.4 1 0 0 1 1 1 0 CASP C terminal SlyX PF04102.12 AIO02225.1 - 5.9 7.6 15.8 6.2 7.5 1.8 3.1 3 0 0 3 3 3 0 SlyX DUF4686 PF15742.5 AIO02225.1 - 6.5 5.8 18.7 60 2.6 18.8 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4686) Pkinase PF00069.25 AIO02226.1 - 3e-55 187.4 0.0 4e-55 187.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 AIO02226.1 - 6.7e-31 107.5 0.0 9.4e-31 107.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 AIO02226.1 - 0.00062 18.6 0.0 0.00099 18.0 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 AIO02226.1 - 0.0027 17.7 0.9 0.64 9.9 0.1 2.7 2 1 1 3 3 3 2 Phosphotransferase enzyme family Kinase-like PF14531.6 AIO02226.1 - 0.18 11.1 0.0 0.35 10.1 0.0 1.4 1 0 0 1 1 1 0 Kinase-like HA2 PF04408.23 AIO02227.1 - 3.7e-17 62.6 0.0 1e-16 61.1 0.0 1.9 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.31 AIO02227.1 - 2.7e-15 56.7 0.0 8.3e-15 55.1 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 AIO02227.1 - 8.8e-09 35.4 0.0 2e-08 34.2 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase OB_NTP_bind PF07717.16 AIO02227.1 - 3e-06 27.5 0.0 9.1e-06 25.9 0.0 1.9 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold T2SSE PF00437.20 AIO02227.1 - 0.00018 20.7 0.0 0.00039 19.6 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein Sigma54_activ_2 PF14532.6 AIO02227.1 - 0.0026 17.9 0.0 0.41 10.8 0.0 2.9 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_22 PF13401.6 AIO02227.1 - 0.0032 17.7 0.4 0.042 14.1 0.4 2.6 1 1 0 1 1 1 1 AAA domain ATPase PF06745.13 AIO02227.1 - 0.0041 16.5 0.0 0.0089 15.4 0.0 1.5 1 0 0 1 1 1 1 KaiC AAA_25 PF13481.6 AIO02227.1 - 0.019 14.5 0.1 0.65 9.5 0.0 2.4 2 0 0 2 2 2 0 AAA domain RsgA_GTPase PF03193.16 AIO02227.1 - 0.054 13.4 0.0 0.27 11.1 0.0 2.0 2 0 0 2 2 2 0 RsgA GTPase PhoH PF02562.16 AIO02227.1 - 0.056 12.9 0.0 0.13 11.7 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein AAA_23 PF13476.6 AIO02227.1 - 0.083 13.4 0.0 0.2 12.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain cobW PF02492.19 AIO02227.1 - 0.092 12.3 0.2 3.2 7.3 0.1 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_7 PF12775.7 AIO02227.1 - 0.11 11.9 0.0 0.31 10.5 0.0 1.7 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_19 PF13245.6 AIO02227.1 - 0.13 12.5 0.0 0.75 10.1 0.0 2.3 1 1 0 1 1 1 0 AAA domain ResIII PF04851.15 AIO02227.1 - 0.17 11.9 0.0 5 7.1 0.0 2.4 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit AAA_16 PF13191.6 AIO02227.1 - 0.85 10.0 3.7 1.3 9.3 0.0 2.7 2 0 0 2 2 2 0 AAA ATPase domain NifU PF01106.17 AIO02228.1 - 1.7e-24 85.7 0.1 2.9e-24 85.0 0.1 1.4 1 0 0 1 1 1 1 NifU-like domain Nfu_N PF08712.11 AIO02228.1 - 8.7e-13 48.1 0.0 2.6e-12 46.6 0.0 1.8 1 0 0 1 1 1 1 Scaffold protein Nfu/NifU N terminal Glyco_transf_25 PF01755.17 AIO02228.1 - 0.012 15.5 0.1 0.058 13.2 0.0 1.9 2 0 0 2 2 2 0 Glycosyltransferase family 25 (LPS biosynthesis protein) eIF-6 PF01912.18 AIO02229.1 - 3.2e-79 264.9 0.6 4.7e-79 264.4 0.4 1.3 2 0 0 2 2 2 1 eIF-6 family Pkinase PF00069.25 AIO02230.1 - 1.4e-73 247.5 0.0 2.2e-73 246.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 AIO02230.1 - 1.7e-39 135.7 0.0 2.6e-39 135.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 AIO02230.1 - 1.3e-05 24.7 0.0 2.2e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 AIO02230.1 - 0.00062 19.2 0.2 0.0018 17.6 0.2 1.8 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.9 AIO02230.1 - 0.0079 15.7 0.1 0.015 14.9 0.1 1.3 1 0 0 1 1 1 1 PhoP regulatory network protein YrbL APH PF01636.23 AIO02230.1 - 0.008 16.1 0.1 0.38 10.6 0.1 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family Pkinase PF00069.25 AIO02231.1 - 1.8e-52 178.4 0.0 3e-52 177.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 AIO02231.1 - 3.5e-32 111.7 0.0 5.8e-32 111.0 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 AIO02231.1 - 0.0042 17.0 0.0 0.0094 15.9 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family ETRAMP PF09716.10 AIO02231.1 - 0.05 13.7 0.0 0.12 12.4 0.0 1.7 1 0 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) Pkinase_fungal PF17667.1 AIO02231.1 - 0.11 11.3 0.0 0.21 10.3 0.0 1.4 1 0 0 1 1 1 0 Fungal protein kinase Ribonuclease_3 PF00636.26 AIO02232.1 - 9.9e-06 26.1 0.0 0.0017 19.0 0.0 3.3 3 2 0 3 3 3 1 Ribonuclease III domain Ribosomal_S13 PF00416.22 AIO02233.1 - 4.5e-42 143.5 0.3 5.2e-42 143.3 0.3 1.0 1 0 0 1 1 1 1 Ribosomal protein S13/S18 DUF2746 PF10874.8 AIO02233.1 - 0.13 12.7 0.0 0.23 11.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2746) Ribosomal_S13 PF00416.22 AIO02234.1 - 4.5e-42 143.5 0.3 5.2e-42 143.3 0.3 1.0 1 0 0 1 1 1 1 Ribosomal protein S13/S18 DUF2746 PF10874.8 AIO02234.1 - 0.13 12.7 0.0 0.23 11.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2746) AAA_6 PF12774.7 AIO02235.1 - 2.6e-152 506.5 0.0 2e-151 503.6 0.0 2.3 2 0 0 2 2 2 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 AIO02235.1 - 5.4e-111 371.5 12.9 5.4e-111 371.5 12.9 3.2 3 0 0 3 3 3 1 Dynein heavy chain, N-terminal region 2 Dynein_C PF18199.1 AIO02235.1 - 1.5e-101 339.6 10.4 3.7e-100 335.1 0.0 4.9 5 0 0 5 5 5 1 Dynein heavy chain C-terminal domain AAA_8 PF12780.7 AIO02235.1 - 2.6e-98 328.5 0.6 4.9e-97 324.3 0.0 2.8 3 0 0 3 3 3 1 P-loop containing dynein motor region D4 AAA_9 PF12781.7 AIO02235.1 - 8.9e-77 257.1 0.0 8.9e-77 257.1 0.0 4.2 5 0 0 5 5 5 1 ATP-binding dynein motor region AAA_7 PF12775.7 AIO02235.1 - 2.9e-64 215.9 2.8 1.3e-62 210.5 0.0 3.0 3 0 0 3 3 3 1 P-loop containing dynein motor region AAA_lid_11 PF18198.1 AIO02235.1 - 1.2e-52 178.1 0.0 1.4e-51 174.5 0.0 2.7 2 0 0 2 2 2 1 Dynein heavy chain AAA lid domain Dynein_heavy PF03028.15 AIO02235.1 - 1.5e-48 163.8 0.0 4.6e-46 155.8 0.0 4.3 4 0 0 4 4 3 1 Dynein heavy chain region D6 P-loop domain MT PF12777.7 AIO02235.1 - 2.8e-45 154.8 7.8 2.8e-45 154.8 7.8 2.0 2 0 0 2 2 2 1 Microtubule-binding stalk of dynein motor Dynein_AAA_lid PF17852.1 AIO02235.1 - 2.6e-23 82.5 0.3 1.2e-22 80.3 0.1 2.4 2 0 0 2 2 2 1 Dynein heavy chain AAA lid domain AAA_5 PF07728.14 AIO02235.1 - 1.8e-15 57.2 1.5 0.00024 21.1 0.0 7.5 8 2 0 8 8 7 3 AAA domain (dynein-related subfamily) AAA_lid_1 PF17857.1 AIO02235.1 - 1.7e-14 53.8 0.0 6.7e-14 51.9 0.0 2.1 1 0 0 1 1 1 1 AAA+ lid domain AAA_22 PF13401.6 AIO02235.1 - 7.7e-10 39.2 0.2 1e-05 25.9 0.0 4.3 5 0 0 5 5 3 2 AAA domain AAA PF00004.29 AIO02235.1 - 5.5e-06 26.8 0.0 0.18 12.2 0.0 3.4 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 AIO02235.1 - 2.4e-05 24.7 0.1 0.34 11.3 0.0 4.1 4 0 0 4 4 4 2 RNA helicase ATG16 PF08614.11 AIO02235.1 - 7.7e-05 23.0 6.2 7.7e-05 23.0 6.2 3.7 4 0 0 4 4 3 1 Autophagy protein 16 (ATG16) NACHT PF05729.12 AIO02235.1 - 0.00056 19.9 1.2 0.014 15.4 0.0 3.4 3 0 0 3 3 2 1 NACHT domain AAA_16 PF13191.6 AIO02235.1 - 0.0009 19.7 5.7 1.9 8.8 0.0 4.9 5 0 0 5 5 4 2 AAA ATPase domain AAA_30 PF13604.6 AIO02235.1 - 0.0024 17.6 0.0 2.6 7.7 0.1 3.1 3 0 0 3 3 3 1 AAA domain AAA_18 PF13238.6 AIO02235.1 - 0.012 16.2 0.1 3.4 8.2 0.0 4.2 4 0 0 4 4 2 0 AAA domain AAA_24 PF13479.6 AIO02235.1 - 0.029 14.1 0.0 4.8 6.9 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 AIO02235.1 - 0.048 13.8 2.4 1.4 9.1 0.0 3.4 3 0 0 3 3 2 0 AAA domain Rad17 PF03215.15 AIO02235.1 - 0.092 12.7 0.2 17 5.3 0.1 2.9 2 0 0 2 2 2 0 Rad17 P-loop domain MnmE_helical PF12631.7 AIO02235.1 - 0.34 11.1 5.9 2.2 8.4 0.2 3.7 3 0 0 3 3 3 0 MnmE helical domain Med29 PF11568.8 AIO02236.1 - 0.14 12.4 0.0 0.52 10.5 0.0 1.9 2 0 0 2 2 2 0 Mediator complex subunit 29 DUF148 PF02520.17 AIO02237.1 - 0.048 13.8 0.7 0.079 13.1 0.7 1.3 1 0 0 1 1 1 0 Domain of unknown function DUF148 S10_plectin PF03501.15 AIO02238.1 - 9.5e-36 121.8 0.0 1.1e-35 121.5 0.0 1.1 1 0 0 1 1 1 1 Plectin/S10 domain API5 PF05918.11 AIO02238.1 - 1.8 7.3 8.2 2.7 6.7 8.2 1.3 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) S10_plectin PF03501.15 AIO02239.1 - 9.5e-36 121.8 0.0 1.1e-35 121.5 0.0 1.1 1 0 0 1 1 1 1 Plectin/S10 domain API5 PF05918.11 AIO02239.1 - 1.8 7.3 8.2 2.7 6.7 8.2 1.3 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) WD40 PF00400.32 AIO02240.1 - 1.4e-09 38.3 17.2 1.2e-07 32.3 0.4 6.9 7 1 0 7 7 7 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 AIO02240.1 - 1.1e-07 32.0 0.0 1.2 9.5 0.0 5.1 4 2 1 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Clathrin PF00637.20 AIO02240.1 - 0.00035 20.5 1.0 1.3 8.9 0.0 3.8 2 1 2 4 4 4 2 Region in Clathrin and VPS Coatomer_WDAD PF04053.14 AIO02240.1 - 0.00043 19.5 0.0 0.11 11.6 0.1 4.2 4 1 1 5 5 5 1 Coatomer WD associated region TPR_7 PF13176.6 AIO02240.1 - 0.0033 17.3 1.6 0.61 10.2 0.0 4.2 5 1 0 5 5 5 1 Tetratricopeptide repeat SNAP PF14938.6 AIO02240.1 - 0.0035 16.8 0.2 0.0035 16.8 0.2 2.3 1 1 0 1 1 1 1 Soluble NSF attachment protein, SNAP Nic96 PF04097.14 AIO02240.1 - 0.0047 15.4 0.0 0.0093 14.5 0.0 1.4 1 0 0 1 1 1 1 Nup93/Nic96 DUF2802 PF10975.8 AIO02240.1 - 0.0047 17.0 0.1 0.035 14.2 0.1 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF2802) TPR_14 PF13428.6 AIO02240.1 - 0.0051 17.5 7.6 5.1 8.2 0.0 5.6 4 2 2 6 6 6 1 Tetratricopeptide repeat ANAPC3 PF12895.7 AIO02240.1 - 0.0069 16.6 1.8 0.48 10.7 0.0 3.6 2 1 1 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.6 AIO02240.1 - 0.15 12.4 3.5 39 4.6 0.0 4.8 4 1 1 5 5 5 0 Tetratricopeptide repeat PPR PF01535.20 AIO02240.1 - 0.19 12.0 1.7 25 5.4 0.0 4.4 4 0 0 4 4 4 0 PPR repeat TPR_2 PF07719.17 AIO02240.1 - 0.71 10.1 11.3 17 5.8 0.2 5.7 7 0 0 7 7 5 0 Tetratricopeptide repeat TPR_1 PF00515.28 AIO02240.1 - 3.9 7.4 8.3 45 4.1 0.4 4.6 4 0 0 4 4 4 0 Tetratricopeptide repeat LOH1CR12 PF10158.9 AIO02241.1 - 0.63 10.1 3.8 0.68 10.0 0.7 2.5 3 0 0 3 3 3 0 Tumour suppressor protein HTH_15 PF12324.8 AIO02243.1 - 0.18 11.7 0.5 9.3 6.3 0.0 3.5 4 0 0 4 4 4 0 Helix-turn-helix domain of alkylmercury lyase CLAMP PF14769.6 AIO02244.1 - 1.1e-29 102.7 1.4 3e-29 101.4 1.2 1.8 1 1 1 2 2 2 1 Flagellar C1a complex subunit C1a-32 DUF3801 PF12687.7 AIO02244.1 - 0.052 13.6 0.0 0.057 13.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3801) MerR-DNA-bind PF09278.11 AIO02244.1 - 0.9 10.1 4.4 0.85 10.2 0.3 2.7 2 0 0 2 2 2 0 MerR, DNA binding Vir_act_alpha_C PF10400.9 AIO02244.1 - 7.1 7.4 7.3 7.3 7.3 0.5 3.2 3 1 1 4 4 4 0 Virulence activator alpha C-term Ribonuclease_3 PF00636.26 AIO02245.1 - 0.0021 18.7 0.0 0.0066 17.1 0.0 1.9 1 1 0 1 1 1 1 Ribonuclease III domain Ribul_P_3_epim PF00834.19 AIO02245.1 - 0.16 11.3 0.0 0.45 9.9 0.0 1.7 2 0 0 2 2 2 0 Ribulose-phosphate 3 epimerase family WSD PF15613.6 AIO02246.1 - 3.5e-08 33.8 0.5 2e-07 31.4 0.0 2.7 2 0 0 2 2 2 1 Williams-Beuren syndrome DDT (WSD), D-TOX E motif DDT PF02791.17 AIO02246.1 - 0.0056 17.0 0.1 0.017 15.4 0.1 1.9 1 0 0 1 1 1 1 DDT domain Ribosomal_L24e PF01246.20 AIO02247.1 - 2e-21 75.9 1.1 4.9e-21 74.7 1.1 1.7 1 0 0 1 1 1 1 Ribosomal protein L24e SPC12 PF06645.13 AIO02248.1 - 1.8 8.7 6.0 15 5.8 0.8 2.8 3 0 0 3 3 3 0 Microsomal signal peptidase 12 kDa subunit (SPC12) Ribosomal_L24e PF01246.20 AIO02250.1 - 2e-21 75.9 1.1 4.9e-21 74.7 1.1 1.7 1 0 0 1 1 1 1 Ribosomal protein L24e HORMA PF02301.18 AIO02251.1 - 9.6e-49 165.8 0.0 1.3e-48 165.4 0.0 1.2 1 0 0 1 1 1 1 HORMA domain SPEG_u2 PF16650.5 AIO02252.1 - 3.7 7.8 5.2 18 5.6 0.2 2.5 2 0 0 2 2 2 0 Unstructured region on SPEG complex protein 3HCDH_N PF02737.18 AIO02254.1 - 1.1e-56 191.6 1.8 1.4e-56 191.2 1.8 1.1 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.22 AIO02254.1 - 2e-34 118.1 0.1 1.9e-33 114.9 0.0 2.3 3 0 0 3 3 3 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain NAD_binding_2 PF03446.15 AIO02254.1 - 0.032 14.4 3.1 1.6 8.9 3.1 2.2 1 1 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Oxidored_nitro PF00148.19 AIO02254.1 - 0.083 11.6 0.1 0.68 8.6 0.0 1.9 2 0 0 2 2 2 0 Nitrogenase component 1 type Oxidoreductase Pyr_redox PF00070.27 AIO02254.1 - 0.16 12.6 0.7 0.35 11.4 0.4 1.7 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Rhabdo_ncap PF00945.18 AIO02255.1 - 0.13 11.1 0.0 0.28 10.0 0.0 1.4 1 0 0 1 1 1 0 Rhabdovirus nucleocapsid protein Memo PF01875.17 AIO02256.1 - 2.1e-61 207.4 0.0 2.8e-61 207.0 0.0 1.1 1 0 0 1 1 1 1 Memo-like protein CorA PF01544.18 AIO02257.1 - 2.6e-05 23.7 0.4 0.00013 21.4 0.4 2.0 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein Glyco_transf_22 PF03901.17 AIO02260.1 - 8.2e-69 232.8 22.6 1e-68 232.5 22.6 1.1 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family PilX_N PF14341.6 AIO02260.1 - 2.1 8.4 6.7 0.21 11.6 1.0 2.3 2 0 0 2 2 2 0 PilX N-terminal GST_C_6 PF17171.4 AIO02261.1 - 0.046 13.5 0.1 0.37 10.6 0.0 2.0 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain DUF4890 PF16231.5 AIO02262.1 - 0.048 14.1 0.3 0.097 13.2 0.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4890) DUF4709 PF15821.5 AIO02262.1 - 0.11 12.7 0.1 0.27 11.5 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4709) Synthase_beta PF11421.8 AIO02262.1 - 5.9 7.7 13.5 3.2 8.6 0.2 3.7 4 0 0 4 4 4 0 ATP synthase F1 beta subunit PP2C PF00481.21 AIO02263.1 - 4.2e-09 36.4 0.0 1.1e-08 35.1 0.0 1.7 1 1 0 1 1 1 1 Protein phosphatase 2C Agenet PF05641.12 AIO02263.1 - 0.051 14.0 0.0 0.1 13.1 0.0 1.5 1 0 0 1 1 1 0 Agenet domain zf-TFIIB PF13453.6 AIO02263.1 - 0.1 11.9 0.1 1.5 8.2 0.0 2.4 2 0 0 2 2 2 0 Transcription factor zinc-finger DUF5393 PF17371.2 AIO02264.1 - 2.1e-56 191.4 1.7 2.6e-56 191.1 1.7 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF5393) DUF5393 PF17371.2 AIO02265.1 - 2.7e-257 855.2 10.0 3e-257 855.0 10.0 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF5393) S4 PF01479.25 AIO02266.1 - 2.6e-13 49.4 0.3 5.7e-13 48.3 0.3 1.6 1 0 0 1 1 1 1 S4 domain Ribosomal_S4 PF00163.19 AIO02266.1 - 1.1e-07 32.6 0.2 2.4e-07 31.6 0.2 1.8 1 1 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain TyrRSs_C PF16714.5 AIO02266.1 - 0.019 14.7 0.0 0.029 14.2 0.0 1.3 1 0 0 1 1 1 0 Tyrosyl-tRNA synthetase C-terminal domain Glycolytic PF00274.19 AIO02267.1 - 6.5e-143 475.7 0.0 7.3e-143 475.5 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-I PSD4 PF07631.11 AIO02268.1 - 0.019 15.5 5.9 1.1 9.8 1.8 2.5 1 1 0 2 2 2 0 Protein of unknown function (DUF1592) DUF3094 PF11293.8 AIO02268.1 - 0.046 13.4 1.1 1.6 8.5 0.2 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3094) SIP1 PF04938.12 AIO02269.1 - 5.6e-05 22.9 0.0 0.00017 21.4 0.0 2.1 1 1 0 1 1 1 1 Survival motor neuron (SMN) interacting protein 1 (SIP1) BILBO1_N PF18281.1 AIO02270.1 - 3.2e-30 104.4 0.9 6e-30 103.5 0.9 1.5 1 0 0 1 1 1 1 BILBO1 N-terminal domain CENP-F_leu_zip PF10473.9 AIO02270.1 - 0.0081 16.2 11.9 0.018 15.1 9.9 2.0 2 0 0 2 2 2 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 UPF0242 PF06785.11 AIO02270.1 - 0.014 15.5 0.4 0.018 15.2 0.4 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus TAF4 PF05236.14 AIO02270.1 - 0.66 9.7 11.7 1.1 9.0 11.7 1.3 1 0 0 1 1 1 0 Transcription initiation factor TFIID component TAF4 family ADIP PF11559.8 AIO02270.1 - 2.2 8.4 13.0 14 5.7 11.4 2.1 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding GAS PF13851.6 AIO02270.1 - 2.8 7.3 11.2 5.5 6.3 11.2 1.4 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding APG6_N PF17675.1 AIO02270.1 - 6.7 7.2 18.3 54 4.3 18.4 2.2 1 1 0 1 1 1 0 Apg6 coiled-coil region Phage_G PF02306.15 AIO02271.1 - 0.17 11.6 2.0 0.2 11.4 0.4 1.8 1 1 1 2 2 2 0 Major spike protein (G protein) SlyX PF04102.12 AIO02271.1 - 0.52 11.0 8.2 0.33 11.6 3.4 2.4 1 1 1 2 2 2 0 SlyX DnaJ PF00226.31 AIO02272.1 - 2.5e-06 27.5 0.0 5.2e-06 26.5 0.0 1.5 1 0 0 1 1 1 1 DnaJ domain NARP1 PF12569.8 AIO02273.1 - 9.6e-85 285.4 11.1 3.9e-80 270.2 6.6 3.0 2 1 0 3 3 3 2 NMDA receptor-regulated protein 1 TPR_2 PF07719.17 AIO02273.1 - 7.7e-18 63.1 17.3 3.7e-05 23.5 0.0 8.8 9 0 0 9 9 7 3 Tetratricopeptide repeat TPR_19 PF14559.6 AIO02273.1 - 4.1e-11 43.2 18.1 0.00066 20.1 0.0 5.8 6 0 0 6 6 5 3 Tetratricopeptide repeat TPR_1 PF00515.28 AIO02273.1 - 5.6e-11 41.8 15.1 8.8e-06 25.3 0.0 7.3 8 0 0 8 8 7 3 Tetratricopeptide repeat TPR_14 PF13428.6 AIO02273.1 - 5e-10 39.4 25.7 0.021 15.6 0.1 8.9 7 2 3 10 10 10 3 Tetratricopeptide repeat TPR_8 PF13181.6 AIO02273.1 - 9.9e-10 37.9 5.2 0.079 13.2 0.0 6.4 6 0 0 6 6 5 3 Tetratricopeptide repeat TPR_17 PF13431.6 AIO02273.1 - 6e-09 35.7 5.5 0.28 11.7 0.1 5.7 7 0 0 7 7 5 3 Tetratricopeptide repeat TPR_9 PF13371.6 AIO02273.1 - 2.5e-08 34.0 14.8 0.00018 21.6 0.0 6.3 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_11 PF13414.6 AIO02273.1 - 2.9e-06 26.9 2.4 0.042 13.5 0.0 5.8 6 0 0 6 6 6 1 TPR repeat TPR_7 PF13176.6 AIO02273.1 - 4.1e-05 23.3 9.3 2 8.6 0.1 6.6 7 0 0 7 7 6 1 Tetratricopeptide repeat TPR_16 PF13432.6 AIO02273.1 - 5.1e-05 23.8 22.2 0.014 16.0 5.1 6.7 6 2 1 7 7 7 2 Tetratricopeptide repeat TPR_12 PF13424.6 AIO02273.1 - 8.2e-05 22.8 22.9 0.12 12.7 0.0 6.8 7 2 2 9 9 8 3 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 AIO02273.1 - 0.0011 18.9 1.5 9.2 6.4 0.0 5.1 5 0 0 5 5 5 1 Fis1 C-terminal tetratricopeptide repeat ANAPC3 PF12895.7 AIO02273.1 - 0.0014 18.8 16.9 0.17 12.1 0.0 6.1 4 2 3 7 7 7 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_10 PF13374.6 AIO02273.1 - 0.0015 18.4 2.3 3.4 7.7 0.1 4.7 4 0 0 4 4 4 1 Tetratricopeptide repeat zf-PARP PF00645.18 AIO02274.1 - 8.4e-20 71.4 2.2 2.2e-19 70.1 2.2 1.7 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region zf-CCHH PF10283.9 AIO02274.1 - 8e-09 35.3 4.3 1.5e-08 34.5 4.3 1.3 1 0 0 1 1 1 1 PBZ domain ADK PF00406.22 AIO02275.1 - 2.1e-41 141.5 0.0 4.3e-41 140.5 0.0 1.4 1 1 1 2 2 2 1 Adenylate kinase AAA_17 PF13207.6 AIO02275.1 - 1.9e-25 89.8 0.0 1.7e-24 86.8 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 AIO02275.1 - 1.3e-10 41.9 0.1 5e-10 40.0 0.0 1.9 2 1 0 2 2 2 1 AAA domain Hydin_ADK PF17213.3 AIO02275.1 - 0.00021 21.6 0.2 0.0056 17.0 0.0 2.4 1 1 1 2 2 2 1 Hydin Adenylate kinase-like domain AAA_33 PF13671.6 AIO02275.1 - 0.00059 20.0 0.7 0.0018 18.5 0.0 2.2 2 2 0 2 2 2 1 AAA domain Zeta_toxin PF06414.12 AIO02275.1 - 0.01 15.1 0.3 0.044 13.1 0.0 2.0 2 0 0 2 2 2 0 Zeta toxin Thymidylate_kin PF02223.17 AIO02275.1 - 0.028 14.1 0.1 11 5.6 0.0 2.7 3 0 0 3 3 3 0 Thymidylate kinase dNK PF01712.19 AIO02275.1 - 0.067 13.0 0.5 6.6 6.5 0.0 2.9 3 0 0 3 3 3 0 Deoxynucleoside kinase AAA_5 PF07728.14 AIO02275.1 - 0.1 12.6 0.1 3.3 7.7 0.0 2.3 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_28 PF13521.6 AIO02275.1 - 0.13 12.5 0.0 0.3 11.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 AIO02276.1 - 5e-95 314.9 0.0 4.5e-46 156.5 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 AIO02276.1 - 7.6e-27 92.9 8.1 2.1e-13 49.8 0.3 3.1 3 1 0 3 3 2 2 AAA+ lid domain CDC48_N PF02359.18 AIO02276.1 - 1e-19 70.5 0.3 4.4e-19 68.5 0.1 2.3 2 0 0 2 2 1 1 Cell division protein 48 (CDC48), N-terminal domain RuvB_N PF05496.12 AIO02276.1 - 6.8e-14 51.9 0.0 9.1e-06 25.5 0.0 3.0 2 2 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 AIO02276.1 - 1.9e-12 47.9 0.2 0.00046 20.6 0.0 4.0 2 2 1 3 3 3 2 AAA ATPase domain AAA_2 PF07724.14 AIO02276.1 - 6.2e-12 46.0 0.0 3.2e-06 27.4 0.0 2.7 2 1 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_33 PF13671.6 AIO02276.1 - 1.7e-11 44.4 0.0 5.5e-06 26.6 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_5 PF07728.14 AIO02276.1 - 1.9e-10 40.9 0.2 5.2e-05 23.3 0.1 3.4 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) CDC48_2 PF02933.17 AIO02276.1 - 4.9e-10 39.0 0.0 1.2e-09 37.9 0.0 1.7 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), domain 2 AAA_22 PF13401.6 AIO02276.1 - 2e-09 37.8 0.5 0.039 14.2 0.0 4.0 2 2 2 4 4 4 2 AAA domain TIP49 PF06068.13 AIO02276.1 - 9.6e-09 34.9 0.0 0.00039 19.7 0.0 2.5 2 0 0 2 2 2 2 TIP49 P-loop domain AAA_18 PF13238.6 AIO02276.1 - 1.6e-07 31.9 0.0 0.016 15.7 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_14 PF13173.6 AIO02276.1 - 2.2e-07 31.0 0.0 0.0061 16.6 0.0 2.4 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.22 AIO02276.1 - 2.3e-07 31.1 0.0 0.0057 17.0 0.0 3.0 2 0 0 2 2 2 2 RNA helicase Mg_chelatase PF01078.21 AIO02276.1 - 4.4e-07 29.5 0.2 0.031 13.7 0.0 2.6 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 AIO02276.1 - 4.4e-06 26.6 0.0 0.075 12.8 0.0 2.5 2 0 0 2 2 2 2 IstB-like ATP binding protein ABC_tran PF00005.27 AIO02276.1 - 1.4e-05 25.7 0.0 0.055 14.0 0.0 3.1 2 1 0 2 2 2 1 ABC transporter Vps4_C PF09336.10 AIO02276.1 - 1.5e-05 24.9 0.1 0.0011 18.9 0.0 2.7 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain Zeta_toxin PF06414.12 AIO02276.1 - 1.9e-05 24.1 0.0 0.11 11.8 0.0 2.5 2 0 0 2 2 2 2 Zeta toxin AAA_28 PF13521.6 AIO02276.1 - 2.2e-05 24.8 0.0 0.24 11.6 0.0 2.8 3 0 0 3 3 2 2 AAA domain AAA_17 PF13207.6 AIO02276.1 - 2.5e-05 24.7 0.0 0.18 12.2 0.0 2.8 2 0 0 2 2 2 2 AAA domain ATPase_2 PF01637.18 AIO02276.1 - 3.2e-05 24.0 0.1 0.43 10.4 0.0 2.9 2 1 0 2 2 2 2 ATPase domain predominantly from Archaea Parvo_NS1 PF01057.17 AIO02276.1 - 3.6e-05 23.0 0.0 0.056 12.5 0.0 2.2 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 AAA_25 PF13481.6 AIO02276.1 - 4e-05 23.3 1.7 1.4 8.5 0.1 3.6 2 2 1 3 3 3 1 AAA domain NACHT PF05729.12 AIO02276.1 - 5.8e-05 23.1 0.1 0.17 11.8 0.0 3.1 3 0 0 3 3 3 1 NACHT domain AAA_24 PF13479.6 AIO02276.1 - 7.6e-05 22.5 0.0 0.13 12.0 0.0 2.5 2 0 0 2 2 2 2 AAA domain ATPase PF06745.13 AIO02276.1 - 8.5e-05 22.0 1.7 1.5 8.1 0.0 3.6 2 1 1 3 3 3 1 KaiC Sigma54_activat PF00158.26 AIO02276.1 - 0.0001 22.0 0.1 0.7 9.6 0.1 3.2 2 1 0 2 2 2 2 Sigma-54 interaction domain TsaE PF02367.17 AIO02276.1 - 0.00011 22.2 0.0 0.64 10.0 0.0 2.7 3 0 0 3 3 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE Bac_DnaA PF00308.18 AIO02276.1 - 0.00015 21.7 0.0 0.19 11.6 0.0 2.4 2 0 0 2 2 2 1 Bacterial dnaA protein AAA_7 PF12775.7 AIO02276.1 - 0.00019 21.0 0.0 0.49 9.9 0.0 2.7 2 1 0 2 2 2 2 P-loop containing dynein motor region Viral_helicase1 PF01443.18 AIO02276.1 - 0.00022 21.1 0.0 0.015 15.1 0.0 2.3 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase NTPase_1 PF03266.15 AIO02276.1 - 0.00041 20.3 1.1 10 6.0 0.0 4.2 3 1 1 4 4 4 0 NTPase AAA_3 PF07726.11 AIO02276.1 - 0.00047 20.0 0.0 1.4 8.8 0.0 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) NB-ARC PF00931.22 AIO02276.1 - 0.00071 18.8 0.0 0.98 8.6 0.0 2.4 2 0 0 2 2 2 2 NB-ARC domain ResIII PF04851.15 AIO02276.1 - 0.001 19.1 0.0 0.092 12.7 0.0 2.3 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Sigma54_activ_2 PF14532.6 AIO02276.1 - 0.0016 18.6 0.0 0.66 10.1 0.0 2.6 2 0 0 2 2 2 1 Sigma-54 interaction domain PhoH PF02562.16 AIO02276.1 - 0.0025 17.3 0.1 1.4 8.3 0.0 2.5 2 0 0 2 2 2 1 PhoH-like protein DUF2075 PF09848.9 AIO02276.1 - 0.0031 16.8 0.0 0.94 8.7 0.0 2.3 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) Rad17 PF03215.15 AIO02276.1 - 0.0076 16.2 0.0 2.1 8.2 0.0 2.5 2 0 0 2 2 2 1 Rad17 P-loop domain DUF815 PF05673.13 AIO02276.1 - 0.012 14.8 0.0 5.1 6.2 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF815) Molydop_binding PF01568.21 AIO02276.1 - 0.02 14.9 0.0 0.045 13.8 0.0 1.6 1 0 0 1 1 1 0 Molydopterin dinucleotide binding domain AAA_19 PF13245.6 AIO02276.1 - 0.025 14.9 1.8 7.4 6.9 0.1 3.4 3 1 1 4 4 2 0 AAA domain Cytidylate_kin2 PF13189.6 AIO02276.1 - 0.032 14.4 1.0 1.7 8.7 0.0 2.8 4 0 0 4 4 2 0 Cytidylate kinase-like family Cytidylate_kin PF02224.18 AIO02276.1 - 0.034 13.9 0.0 5.5 6.7 0.0 2.6 2 0 0 2 2 2 0 Cytidylate kinase AAA_11 PF13086.6 AIO02276.1 - 0.041 13.7 0.0 12 5.6 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 AIO02276.1 - 0.046 13.5 0.0 7.3 6.4 0.0 2.7 2 0 0 2 2 2 0 P-loop containing region of AAA domain DEAD PF00270.29 AIO02276.1 - 0.047 13.5 0.2 5.4 6.7 0.0 3.4 4 0 0 4 4 4 0 DEAD/DEAH box helicase SKI PF01202.22 AIO02276.1 - 0.057 13.5 0.1 18 5.5 0.0 2.5 2 0 0 2 2 2 0 Shikimate kinase AAA_23 PF13476.6 AIO02276.1 - 0.066 13.7 0.2 24 5.4 0.0 2.8 2 1 0 2 2 2 0 AAA domain TEX19 PF15553.6 AIO02276.1 - 0.07 13.1 0.1 0.13 12.2 0.1 1.4 1 0 0 1 1 1 0 Testis-expressed protein 19 AAA_30 PF13604.6 AIO02276.1 - 0.079 12.7 0.1 9.5 5.9 0.0 2.6 2 0 0 2 2 2 0 AAA domain CPT PF07931.12 AIO02276.1 - 0.12 12.2 0.0 3.9 7.3 0.0 2.5 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein Zot PF05707.12 AIO02276.1 - 0.14 11.8 0.0 1.8 8.1 0.0 2.6 2 1 0 2 2 2 0 Zonular occludens toxin (Zot) KAP_NTPase PF07693.14 AIO02276.1 - 0.15 11.3 0.1 6 6.0 0.0 3.0 2 2 1 4 4 4 0 KAP family P-loop domain AFG1_ATPase PF03969.16 AIO02276.1 - 0.17 10.8 1.6 11 4.8 0.0 2.9 3 0 0 3 3 3 0 AFG1-like ATPase Aa_trans PF01490.18 AIO02277.1 - 4.5e-41 140.9 24.1 5.7e-41 140.6 24.1 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein DUF21 PF01595.20 AIO02277.1 - 3.3 7.4 9.4 0.96 9.1 0.0 3.0 3 1 0 3 3 3 0 Cyclin M transmembrane N-terminal domain Trypsin_2 PF13365.6 AIO02278.1 - 2.2e-05 25.4 0.1 3.4e-05 24.8 0.1 1.3 1 0 0 1 1 1 1 Trypsin-like peptidase domain Hrs_helical PF12210.8 AIO02279.1 - 0.095 13.2 6.1 0.069 13.7 1.3 2.4 2 0 0 2 2 2 0 Hepatocyte growth factor-regulated tyrosine kinase substrate DUF4407 PF14362.6 AIO02279.1 - 0.35 10.2 4.8 0.72 9.2 4.8 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) T4SS PF07996.11 AIO02279.1 - 6.6 7.1 9.2 19 5.6 0.1 2.9 2 1 1 3 3 3 0 Type IV secretion system proteins ARL2_Bind_BART PF11527.8 AIO02280.1 - 9.9e-31 106.2 0.1 9.9e-31 106.2 0.1 1.8 2 0 0 2 2 2 1 The ARF-like 2 binding protein BART UIM PF02809.20 AIO02280.1 - 0.0017 18.1 1.4 0.0017 18.1 1.4 3.1 3 0 0 3 3 3 1 Ubiquitin interaction motif COMPASS-Shg1 PF05205.12 AIO02280.1 - 6.2 7.6 7.7 83 4.0 3.3 3.2 3 0 0 3 3 3 0 COMPASS (Complex proteins associated with Set1p) component shg1 zf-RanBP PF00641.18 AIO02281.1 - 0.0063 15.8 5.0 0.0063 15.8 5.0 15.5 13 2 1 14 14 14 5 Zn-finger in Ran binding protein and others DZR PF12773.7 AIO02281.1 - 0.39 10.8 144.0 0.025 14.6 12.4 10.4 8 2 2 10 10 10 0 Double zinc ribbon HTH_31 PF13560.6 AIO02281.1 - 4.1 7.8 8.3 5.8 7.4 1.9 3.3 3 0 0 3 3 3 0 Helix-turn-helix domain zf-RanBP PF00641.18 AIO02282.1 - 1.1e-20 72.6 85.3 7.4e-08 31.6 2.9 9.7 10 0 0 10 10 10 8 Zn-finger in Ran binding protein and others DZR PF12773.7 AIO02282.1 - 2.7e-06 27.3 65.0 0.011 15.8 7.0 6.6 4 3 2 6 6 6 6 Double zinc ribbon Vps36-NZF-N PF16988.5 AIO02282.1 - 0.18 11.2 0.1 0.18 11.2 0.1 8.1 6 2 3 9 9 9 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain EF1_GNE PF00736.19 AIO02283.1 - 1.8e-26 92.2 1.1 3e-26 91.4 1.1 1.4 1 0 0 1 1 1 1 EF-1 guanine nucleotide exchange domain Mrr_cat PF04471.12 AIO02283.1 - 0.029 14.4 1.1 1.8 8.6 0.5 2.9 1 1 1 2 2 2 0 Restriction endonuclease GST_C_6 PF17171.4 AIO02283.1 - 0.099 12.4 0.0 0.43 10.4 0.0 2.1 2 1 0 2 2 2 0 Glutathione S-transferase, C-terminal domain Chorein_N PF12624.7 AIO02284.1 - 7.4e-24 84.1 0.2 9.3e-11 41.9 0.0 2.8 2 0 0 2 2 2 2 N-terminal region of Chorein or VPS13 VPS13_C PF16909.5 AIO02284.1 - 2.8e-11 43.5 0.0 3.8e-07 30.1 0.0 2.4 2 0 0 2 2 2 2 Vacuolar-sorting-associated 13 protein C-terminal VPS13 PF16908.5 AIO02284.1 - 0.00016 21.6 1.8 0.0029 17.4 1.8 2.5 1 1 0 1 1 1 1 Vacuolar sorting-associated protein 13, N-terminal NO_synthase PF02898.15 AIO02284.1 - 0.27 10.2 0.7 0.45 9.5 0.7 1.2 1 0 0 1 1 1 0 Nitric oxide synthase, oxygenase domain DUF5582 PF17819.1 AIO02285.1 - 0.028 14.9 0.6 0.05 14.1 0.6 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5582) EF-hand_7 PF13499.6 AIO02285.1 - 0.14 12.7 0.0 0.32 11.5 0.0 1.7 1 1 0 1 1 1 0 EF-hand domain pair Kelch_4 PF13418.6 AIO02287.1 - 6.7e-15 54.8 0.2 5e-06 26.4 0.0 5.1 5 0 0 5 5 5 3 Galactose oxidase, central domain Kelch_1 PF01344.25 AIO02287.1 - 3.1e-10 39.5 0.1 5.5e-05 22.7 0.0 3.7 3 0 0 3 3 3 2 Kelch motif Kelch_5 PF13854.6 AIO02287.1 - 4.8e-09 36.0 0.1 0.002 18.1 0.0 3.9 3 0 0 3 3 3 2 Kelch motif Kelch_6 PF13964.6 AIO02287.1 - 2.4e-08 34.0 0.4 0.037 14.3 0.0 4.4 4 0 0 4 4 4 3 Kelch motif Kelch_2 PF07646.15 AIO02287.1 - 1.2e-07 31.4 0.1 0.024 14.6 0.0 4.5 4 0 0 4 4 4 2 Kelch motif Kelch_3 PF13415.6 AIO02287.1 - 3.9e-07 30.2 5.7 0.003 17.8 0.0 5.2 6 0 0 6 6 6 2 Galactose oxidase, central domain DUF4719 PF15843.5 AIO02288.1 - 0.051 13.7 0.6 0.2 11.8 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4719) DUF4090 PF13319.6 AIO02290.1 - 0.14 12.4 0.0 0.42 10.9 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF4090) Med30 PF11315.8 AIO02291.1 - 0.038 14.2 0.6 0.097 12.9 0.4 1.7 1 1 1 2 2 2 0 Mediator complex subunit 30 P4Ha_N PF08336.11 AIO02291.1 - 0.059 13.4 0.2 0.079 13.0 0.2 1.3 1 0 0 1 1 1 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region Complex1_LYR_2 PF13233.6 AIO02291.1 - 0.061 14.1 0.0 0.24 12.2 0.0 1.9 1 1 0 1 1 1 0 Complex1_LYR-like AAA_23 PF13476.6 AIO02291.1 - 0.076 13.5 0.5 0.089 13.3 0.5 1.1 1 0 0 1 1 1 0 AAA domain RNA_polI_A14 PF08203.11 AIO02291.1 - 0.1 13.3 0.2 0.2 12.4 0.2 1.5 1 0 0 1 1 1 0 Yeast RNA polymerase I subunit RPA14 Laminin_II PF06009.12 AIO02291.1 - 0.33 11.0 3.7 0.79 9.7 0.4 2.1 2 0 0 2 2 2 0 Laminin Domain II Pkinase PF00069.25 AIO02292.1 - 1.4e-56 191.8 0.0 2e-56 191.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 AIO02292.1 - 2.3e-35 122.1 0.0 3.6e-35 121.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 AIO02292.1 - 7.1e-06 25.5 0.0 1.9e-05 24.1 0.0 1.6 1 1 1 2 2 2 1 Kinase-like PH PF00169.29 AIO02292.1 - 0.0002 21.8 0.3 0.00074 20.0 0.3 1.9 1 1 0 1 1 1 1 PH domain PH_11 PF15413.6 AIO02292.1 - 0.00068 20.0 0.0 0.0015 18.9 0.0 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain PH_9 PF15410.6 AIO02292.1 - 0.044 14.1 0.1 0.15 12.5 0.1 1.9 1 1 0 1 1 1 0 Pleckstrin homology domain PH_4 PF15404.6 AIO02292.1 - 0.056 13.2 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 Pleckstrin homology domain Pkinase_fungal PF17667.1 AIO02292.1 - 0.14 10.9 0.0 0.22 10.2 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Pkinase PF00069.25 AIO02293.1 - 4.3e-53 180.3 0.0 6.4e-53 179.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 AIO02293.1 - 2.2e-35 122.2 0.0 4.5e-35 121.2 0.0 1.4 2 0 0 2 2 2 1 Protein tyrosine kinase PH PF00169.29 AIO02293.1 - 4.3e-07 30.4 0.0 1.2e-06 29.0 0.0 1.8 1 1 0 1 1 1 1 PH domain Kinase-like PF14531.6 AIO02293.1 - 1e-06 28.3 0.0 1.8e-06 27.5 0.0 1.4 1 0 0 1 1 1 1 Kinase-like PH_9 PF15410.6 AIO02293.1 - 0.03 14.7 0.0 0.077 13.4 0.0 1.7 1 0 0 1 1 1 0 Pleckstrin homology domain PH_11 PF15413.6 AIO02293.1 - 0.07 13.5 0.1 0.56 10.6 0.1 2.2 1 1 0 1 1 1 0 Pleckstrin homology domain ELMO_CED12 PF04727.13 AIO02294.1 - 6.9e-34 117.5 0.0 9.4e-34 117.0 0.0 1.2 1 0 0 1 1 1 1 ELMO/CED-12 family zf-B_box PF00643.24 AIO02295.1 - 1e-07 31.9 25.1 2e-07 31.1 7.5 3.7 5 0 0 5 5 5 2 B-box zinc finger Baculo_PEP_C PF04513.12 AIO02295.1 - 0.00025 21.1 0.0 0.00044 20.3 0.0 1.3 1 0 0 1 1 1 1 Baculovirus polyhedron envelope protein, PEP, C terminus Apolipoprotein PF01442.18 AIO02295.1 - 0.022 14.6 3.5 0.041 13.8 3.5 1.4 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain Spectrin PF00435.21 AIO02295.1 - 0.15 12.6 0.8 0.37 11.3 0.8 1.7 1 0 0 1 1 1 0 Spectrin repeat LRR_4 PF12799.7 AIO02296.1 - 2.7e-17 62.6 5.1 0.0011 19.4 0.1 5.5 3 1 1 5 5 5 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 AIO02296.1 - 1.5e-12 47.1 8.9 2.2e-05 24.1 0.2 4.8 4 1 1 5 5 5 5 Leucine rich repeat LRR_9 PF14580.6 AIO02296.1 - 6.5e-07 29.0 0.4 0.01 15.4 0.0 2.5 1 1 0 2 2 2 2 Leucine-rich repeat LRR_5 PF13306.6 AIO02296.1 - 0.0013 18.7 0.0 0.0023 17.9 0.0 1.3 1 0 0 1 1 1 1 BspA type Leucine rich repeat region (6 copies) DUF4407 PF14362.6 AIO02297.1 - 0.0028 17.1 23.6 0.0041 16.5 13.8 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF4407) DUF5340 PF17275.2 AIO02297.1 - 0.56 10.4 4.4 1.3 9.2 2.8 2.4 2 0 0 2 2 2 0 Family of unknown function (DUF5340) STAG PF08514.11 AIO02299.1 - 1.3e-21 76.6 0.4 5.5e-21 74.6 0.4 2.1 1 0 0 1 1 1 1 STAG domain Fe_dep_repr_C PF02742.15 AIO02299.1 - 0.1 12.7 0.1 0.29 11.2 0.1 1.8 1 0 0 1 1 1 0 Iron dependent repressor, metal binding and dimerisation domain IFT43 PF15305.6 AIO02300.1 - 0.078 13.2 1.3 0.14 12.4 0.6 1.6 2 0 0 2 2 2 0 Intraflagellar transport protein 43 Proteasome PF00227.26 AIO02301.1 - 4.5e-56 189.4 0.1 5.6e-56 189.1 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 AIO02301.1 - 2.5e-13 49.4 0.0 6.5e-13 48.1 0.0 1.8 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature zf-CCHC PF00098.23 AIO02302.1 - 3.5e-42 140.7 39.3 8e-10 38.3 3.1 5.1 5 0 0 5 5 5 5 Zinc knuckle zf-CCHC_3 PF13917.6 AIO02302.1 - 3.5e-13 49.3 27.3 0.0097 15.9 0.9 5.0 1 1 4 5 5 5 5 Zinc knuckle zf-CCHC_4 PF14392.6 AIO02302.1 - 4.6e-08 32.7 28.5 0.092 12.5 1.0 5.0 5 0 0 5 5 5 5 Zinc knuckle zf-CCHC_6 PF15288.6 AIO02302.1 - 3.9e-05 23.4 29.8 0.067 13.0 0.9 5.1 2 2 3 5 5 5 4 Zinc knuckle zf-CCHC_2 PF13696.6 AIO02302.1 - 0.00014 21.6 29.1 0.37 10.7 2.1 5.3 5 0 0 5 5 5 4 Zinc knuckle HscB_4_cys PF18256.1 AIO02302.1 - 0.068 13.0 25.4 9.5 6.1 1.1 5.5 5 0 0 5 5 5 0 Co-chaperone HscB tetracysteine metal binding motif zf-CCHC_5 PF14787.6 AIO02302.1 - 0.097 12.4 30.3 1.6 8.5 0.5 5.1 5 0 0 5 5 5 0 GAG-polyprotein viral zinc-finger TRAF6_Z2 PF18048.1 AIO02302.1 - 0.14 12.2 12.6 19 5.4 0.1 5.3 5 0 0 5 5 5 0 TNF receptor-associated factor 6 zinc finger 2 zf-CCHC PF00098.23 AIO02303.1 - 3.1e-42 140.8 40.7 8e-10 38.3 3.1 5.1 5 0 0 5 5 5 5 Zinc knuckle zf-CCHC_3 PF13917.6 AIO02303.1 - 2.3e-13 49.9 27.6 0.0097 15.9 0.9 5.0 1 1 4 5 5 5 5 Zinc knuckle zf-CCHC_4 PF14392.6 AIO02303.1 - 3.1e-08 33.2 28.8 0.092 12.5 1.0 5.0 5 0 0 5 5 5 5 Zinc knuckle zf-CCHC_6 PF15288.6 AIO02303.1 - 1.6e-05 24.6 31.1 0.019 14.8 1.7 5.1 2 2 3 5 5 5 3 Zinc knuckle zf-CCHC_2 PF13696.6 AIO02303.1 - 0.0032 17.3 29.3 1.2 9.1 1.0 5.3 5 0 0 5 5 5 4 Zinc knuckle TRAF6_Z2 PF18048.1 AIO02303.1 - 0.035 14.2 13.2 19 5.5 0.1 5.3 5 0 0 5 5 5 0 TNF receptor-associated factor 6 zinc finger 2 HscB_4_cys PF18256.1 AIO02303.1 - 0.07 13.0 25.8 8.5 6.3 1.4 5.5 5 0 0 5 5 5 0 Co-chaperone HscB tetracysteine metal binding motif zf-CCHC_5 PF14787.6 AIO02303.1 - 0.071 12.8 30.1 1.6 8.5 0.5 5.1 5 0 0 5 5 5 0 GAG-polyprotein viral zinc-finger Ntox16 PF15523.6 AIO02303.1 - 4.2 7.7 20.7 1.8 8.8 0.2 4.5 1 1 3 4 4 4 0 Novel toxin 16 Clathrin PF00637.20 AIO02304.1 - 5.5e-160 525.6 43.2 4.2e-27 94.8 2.3 8.3 8 0 0 8 8 8 8 Region in Clathrin and VPS Clathrin_H_link PF13838.6 AIO02304.1 - 4.4e-18 65.0 0.3 3.9e-17 61.9 0.0 2.9 3 0 0 3 3 3 1 Clathrin-H-link Clathrin-link PF09268.10 AIO02304.1 - 4.3e-09 35.6 0.1 1.2e-08 34.1 0.1 1.8 1 0 0 1 1 1 1 Clathrin, heavy-chain linker Clathrin_propel PF01394.20 AIO02304.1 - 3e-08 33.6 0.1 1.3 9.4 0.0 5.2 5 0 0 5 5 5 3 Clathrin propeller repeat ACDC PF14733.6 AIO02304.1 - 0.0033 17.7 0.4 8.6 6.8 0.0 4.2 3 0 0 3 3 3 1 AP2-coincident C-terminal TPR_1 PF00515.28 AIO02304.1 - 0.069 13.0 5.6 16 5.5 0.1 5.3 5 0 0 5 5 5 0 Tetratricopeptide repeat Mic1 PF07035.12 AIO02304.1 - 0.069 12.9 6.6 0.4 10.4 0.0 4.8 6 0 0 6 6 6 0 Colon cancer-associated protein Mic1-like PDDEXK_10 PF07788.11 AIO02304.1 - 0.098 12.6 3.7 1.4 8.9 0.1 3.6 3 0 0 3 3 3 0 PD-(D/E)XK nuclease superfamily Egg_lysin PF01303.17 AIO02304.1 - 0.25 11.6 3.0 6.9 6.9 0.3 3.2 3 0 0 3 3 3 0 Egg lysin (Sperm-lysin) zf-CCHC PF00098.23 AIO02305.1 - 2e-37 125.6 48.9 2.4e-07 30.5 1.9 6.1 6 0 0 6 6 6 6 Zinc knuckle zf-CCHC_3 PF13917.6 AIO02305.1 - 8.1e-08 32.1 35.6 0.023 14.7 3.1 5.4 1 1 4 5 5 5 4 Zinc knuckle zf-CCHC_4 PF14392.6 AIO02305.1 - 1.3e-07 31.2 33.8 0.12 12.1 1.6 6.0 6 0 0 6 6 6 6 Zinc knuckle zf-CCHC_2 PF13696.6 AIO02305.1 - 2.6e-07 30.4 45.6 4.4e-05 23.2 2.4 6.2 6 0 0 6 6 6 5 Zinc knuckle zf-CCHC_5 PF14787.6 AIO02305.1 - 3.2e-05 23.5 38.5 0.016 14.9 0.4 5.9 4 2 2 6 6 6 5 GAG-polyprotein viral zinc-finger zf-C3HC4_3 PF13920.6 AIO02305.1 - 9.4 6.2 28.8 0.93 9.4 3.6 4.3 3 1 1 4 4 4 0 Zinc finger, C3HC4 type (RING finger) zf-CCHC PF00098.23 AIO02306.1 - 2.6e-67 220.1 77.8 5.6e-09 35.7 2.5 8.2 8 0 0 8 8 8 8 Zinc knuckle zf-CCHC_3 PF13917.6 AIO02306.1 - 2.7e-26 91.2 45.6 0.00058 19.8 0.4 8.1 5 1 3 8 8 8 8 Zinc knuckle zf-CCHC_2 PF13696.6 AIO02306.1 - 1.1e-12 47.5 57.5 0.00032 20.5 1.9 8.4 8 0 0 8 8 8 7 Zinc knuckle zf-CCHC_5 PF14787.6 AIO02306.1 - 3.5e-09 36.2 56.3 0.45 10.3 1.3 8.2 8 0 0 8 8 8 8 GAG-polyprotein viral zinc-finger zf-CCHC_4 PF14392.6 AIO02306.1 - 3.8e-07 29.7 46.0 2 8.2 0.3 8.1 8 0 0 8 8 8 8 Zinc knuckle Gla PF00594.20 AIO02306.1 - 0.031 14.5 4.8 41 4.5 0.0 4.8 5 0 0 5 5 5 0 Vitamin K-dependent carboxylation/gamma-carboxyglutamic (GLA) domain TRAF6_Z2 PF18048.1 AIO02306.1 - 0.057 13.5 28.5 38 4.5 0.1 7.9 8 0 0 8 8 8 0 TNF receptor-associated factor 6 zinc finger 2 Neil1-DNA_bind PF09292.10 AIO02306.1 - 0.077 13.0 4.2 57 3.8 0.1 5.0 6 0 0 6 6 6 0 Endonuclease VIII-like 1, DNA bind zf-CCHC_6 PF15288.6 AIO02306.1 - 0.24 11.3 65.9 1.8 8.5 2.0 8.2 7 1 1 8 8 8 0 Zinc knuckle Ntox16 PF15523.6 AIO02306.1 - 0.86 9.9 40.1 2.3 8.5 0.9 7.1 6 1 0 7 7 7 0 Novel toxin 16 Proteasome PF00227.26 AIO02307.1 - 1.5e-48 164.8 0.2 1.8e-48 164.5 0.2 1.1 1 0 0 1 1 1 1 Proteasome subunit S4 PF01479.25 AIO02308.1 - 2.5e-06 27.1 0.1 3.6e-05 23.4 0.0 2.5 2 0 0 2 2 2 1 S4 domain PseudoU_synth_2 PF00849.22 AIO02308.1 - 2.9e-05 24.2 0.0 5.3e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 RNA pseudouridylate synthase Q_salvage PF10343.9 AIO02309.1 - 5.1e-17 62.4 0.0 4.9e-15 55.9 0.0 2.5 3 0 0 3 3 3 2 Potential Queuosine, Q, salvage protein family Ank PF00023.30 AIO02309.1 - 0.045 14.2 0.0 0.25 11.9 0.0 2.3 2 0 0 2 2 2 0 Ankyrin repeat Peptidase_M76 PF09768.9 AIO02311.1 - 2.1e-58 196.9 0.2 1.2e-57 194.4 0.2 1.9 1 1 0 1 1 1 1 Peptidase M76 family GPI2 PF06432.11 AIO02313.1 - 5.6e-68 229.4 13.8 6.7e-68 229.2 13.8 1.1 1 0 0 1 1 1 1 Phosphatidylinositol N-acetylglucosaminyltransferase Beach PF02138.18 AIO02314.1 - 1.9e-106 355.5 0.0 2.7e-106 355.0 0.0 1.2 1 0 0 1 1 1 1 Beige/BEACH domain PH_BEACH PF14844.6 AIO02314.1 - 1.1e-20 73.5 0.0 2.2e-20 72.6 0.0 1.5 1 0 0 1 1 1 1 PH domain associated with Beige/BEACH Laminin_G_3 PF13385.6 AIO02314.1 - 3.4e-05 24.0 0.0 9.7e-05 22.6 0.0 1.8 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily Sec34 PF04136.15 AIO02315.1 - 1.9e-12 47.3 1.2 1.9e-12 47.3 1.2 2.3 2 0 0 2 2 2 1 Sec34-like family DUF5329 PF17263.2 AIO02315.1 - 0.022 14.9 0.5 0.094 12.9 0.1 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5329) Lactonase PF10282.9 AIO02317.1 - 0.02 14.2 0.0 0.055 12.7 0.0 1.8 2 0 0 2 2 2 0 Lactonase, 7-bladed beta-propeller Aldedh PF00171.22 AIO02318.1 - 2.4e-166 553.8 0.1 2.8e-166 553.6 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF3253 PF11625.8 AIO02318.1 - 0.042 14.1 0.3 0.13 12.5 0.3 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3253) UxaC PF02614.14 AIO02318.1 - 0.3 9.9 0.0 0.42 9.4 0.0 1.1 1 0 0 1 1 1 0 Glucuronate isomerase TPR_2 PF07719.17 AIO02320.1 - 1.5e-13 49.7 11.9 0.026 14.6 0.0 9.6 9 1 1 10 10 10 3 Tetratricopeptide repeat TPR_1 PF00515.28 AIO02320.1 - 2.1e-13 49.4 5.0 0.01 15.6 0.0 8.7 10 0 0 10 10 9 3 Tetratricopeptide repeat TPR_9 PF13371.6 AIO02320.1 - 6.9e-11 42.1 9.6 7.1e-05 22.9 0.2 5.3 4 1 0 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.6 AIO02320.1 - 1.1e-09 38.8 13.0 7.3e-05 23.3 0.3 5.7 5 1 0 5 5 3 3 Tetratricopeptide repeat TPR_19 PF14559.6 AIO02320.1 - 4.2e-09 36.8 17.9 0.011 16.2 0.3 7.2 5 3 2 7 7 7 3 Tetratricopeptide repeat TPR_11 PF13414.6 AIO02320.1 - 5.3e-08 32.4 1.1 0.0021 17.7 0.1 4.7 4 1 1 5 5 5 2 TPR repeat TPR_8 PF13181.6 AIO02320.1 - 1.4e-06 28.1 3.7 2.3 8.7 0.0 7.3 8 1 2 10 10 8 2 Tetratricopeptide repeat TPR_17 PF13431.6 AIO02320.1 - 1.5e-06 28.2 1.7 0.47 10.9 0.0 4.4 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.6 AIO02320.1 - 1.8e-05 24.9 10.6 0.43 10.9 0.0 6.3 6 1 0 7 7 6 2 Tetratricopeptide repeat TPR_14 PF13428.6 AIO02320.1 - 5.8e-05 23.6 22.0 0.16 12.9 0.0 8.2 5 3 2 8 8 8 1 Tetratricopeptide repeat ANAPC3 PF12895.7 AIO02320.1 - 6e-05 23.2 8.0 0.65 10.3 0.1 5.2 5 1 0 5 5 5 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_15 PF13429.6 AIO02320.1 - 0.016 14.5 0.7 3.1 6.9 0.0 3.6 3 1 0 4 4 4 0 Tetratricopeptide repeat TPR_20 PF14561.6 AIO02320.1 - 0.021 15.2 0.3 0.38 11.1 0.0 3.2 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_21 PF09976.9 AIO02320.1 - 0.043 13.5 0.0 0.63 9.7 0.0 2.4 1 1 1 2 2 2 0 Tetratricopeptide repeat-like domain TPR_7 PF13176.6 AIO02320.1 - 0.61 10.2 14.4 25 5.2 0.0 6.8 6 2 2 8 8 8 0 Tetratricopeptide repeat XRN_N PF03159.18 AIO02321.1 - 4.2e-85 285.0 0.0 4.2e-85 285.0 0.0 2.2 2 1 0 2 2 2 1 XRN 5'-3' exonuclease N-terminus XRN_M PF17846.1 AIO02321.1 - 4.7e-62 210.4 4.3 4.7e-62 210.4 4.3 3.3 2 2 0 2 2 2 1 Xrn1 helical domain HrpA_pilin PF09589.10 AIO02322.1 - 1.6 9.5 0.0 1.6 9.5 0.0 2.9 2 0 0 2 2 2 0 HrpA pilus formation protein MORN PF02493.20 AIO02323.1 - 2.2e-50 165.7 89.2 5.9e-07 29.0 0.4 19.7 22 0 0 22 22 22 13 MORN repeat DUF1302 PF06980.11 AIO02323.1 - 0.0097 14.6 0.1 0.015 13.9 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1302) DUF3048_C PF17479.2 AIO02323.1 - 0.37 11.2 7.6 3 8.3 0.2 4.4 4 1 1 5 5 5 0 Protein of unknown function (DUF3048) C-terminal domain Ras PF00071.22 AIO02324.1 - 1.3e-13 50.8 0.0 2.1e-13 50.2 0.0 1.3 1 0 0 1 1 1 1 Ras family Roc PF08477.13 AIO02324.1 - 1.8e-10 41.0 0.0 3.9e-10 40.0 0.0 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 AIO02324.1 - 0.012 15.7 0.0 0.023 14.7 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase DEAD PF00270.29 AIO02326.1 - 1.6e-42 145.2 0.0 3.2e-42 144.3 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 AIO02326.1 - 2.4e-23 82.6 0.0 1.7e-22 79.8 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 AIO02326.1 - 7.9e-15 54.8 0.1 1.6e-14 53.8 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) DEAD PF00270.29 AIO02327.1 - 5.6e-46 156.5 0.1 5.5e-45 153.3 0.1 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 AIO02327.1 - 2.3e-28 98.8 0.1 2.5e-27 95.4 0.0 2.7 4 0 0 4 4 4 1 Helicase conserved C-terminal domain ResIII PF04851.15 AIO02327.1 - 5.4e-05 23.3 0.0 0.00018 21.6 0.0 1.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 AIO02327.1 - 0.0003 20.1 0.0 0.00054 19.3 0.0 1.4 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase Ribosomal_S5_C PF03719.15 AIO02328.1 - 4e-11 42.2 0.2 6.4e-11 41.6 0.2 1.3 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain Ribosomal_S5 PF00333.20 AIO02328.1 - 1.1e-06 28.5 0.0 2.1e-06 27.6 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S5, N-terminal domain DUF1918 PF08940.11 AIO02328.1 - 0.14 11.8 0.0 0.61 9.7 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF1918) MVP_shoulder PF11978.8 AIO02329.1 - 1.3e-44 151.0 0.0 2.1e-44 150.3 0.0 1.4 1 0 0 1 1 1 1 Shoulder domain Vault PF01505.18 AIO02329.1 - 1.4e-28 98.8 0.0 2.9e-12 46.5 0.0 5.3 5 0 0 5 5 5 3 Major Vault Protein repeat domain Vault_2 PF17794.1 AIO02329.1 - 2.7e-18 66.1 0.0 3.9e-11 43.2 0.1 3.0 2 0 0 2 2 2 2 Major Vault Protein repeat domain Vault_3 PF17795.1 AIO02329.1 - 6.8e-16 58.1 0.0 7.7e-15 54.7 0.0 2.9 2 1 0 2 2 2 1 Major Vault Protein Repeat domain Vault_4 PF17796.1 AIO02329.1 - 9.2e-15 54.5 0.1 3.1e-13 49.6 0.0 3.1 3 0 0 3 3 3 1 Major Vault Protein repeat domain Tfb4 PF03850.14 AIO02329.1 - 0.38 10.2 5.1 0.63 9.5 5.1 1.3 1 0 0 1 1 1 0 Transcription factor Tfb4 CBF PF03914.17 AIO02330.1 - 2e-28 99.6 0.2 2e-28 99.6 0.2 2.4 2 1 0 2 2 2 1 CBF/Mak21 family NOC3p PF07540.11 AIO02330.1 - 1.6e-06 28.5 0.1 5.6e-06 26.7 0.1 2.0 1 0 0 1 1 1 1 Nucleolar complex-associated protein Pep_deformylase PF01327.21 AIO02330.1 - 0.049 13.2 0.1 0.092 12.3 0.1 1.4 1 0 0 1 1 1 0 Polypeptide deformylase DUF4337 PF14235.6 AIO02330.1 - 1.1 9.3 5.5 2.4 8.3 0.9 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4337) Hex_IIIa PF02455.16 AIO02332.1 - 0.19 10.5 0.0 0.35 9.6 0.0 1.3 1 0 0 1 1 1 0 Hexon-associated protein (IIIa) TPR_14 PF13428.6 AIO02332.1 - 8.9 7.4 6.1 14 6.8 0.0 4.4 5 0 0 5 5 5 0 Tetratricopeptide repeat GAS PF13851.6 AIO02334.1 - 1.3e-53 181.3 27.6 1.3e-53 181.3 27.6 3.7 3 1 1 4 4 4 1 Growth-arrest specific micro-tubule binding IFP_35_N PF07334.13 AIO02334.1 - 2 8.5 14.0 2.9 8.0 2.2 3.6 2 1 1 3 3 3 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus Filament PF00038.21 AIO02334.1 - 4.7 6.7 66.8 3.5 7.1 18.1 4.7 1 1 1 2 2 2 0 Intermediate filament protein PBECR1 PF18809.1 AIO02334.1 - 9.3 7.0 12.5 0.59 10.8 3.9 3.1 2 2 1 3 3 3 0 phage-Barnase-EndoU-ColicinE5/D-RelE like nuclease1 TRCF PF03461.15 AIO02335.1 - 0.056 13.8 0.0 10 6.6 0.0 2.9 2 0 0 2 2 2 0 TRCF domain Ribosomal_L37ae PF01780.19 AIO02336.1 - 9.2e-37 125.0 4.5 1e-36 124.9 4.5 1.0 1 0 0 1 1 1 1 Ribosomal L37ae protein family C1_1 PF00130.22 AIO02336.1 - 0.0022 17.8 2.3 0.0032 17.3 2.3 1.2 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-RING_13 PF17977.1 AIO02336.1 - 0.05 13.7 1.1 0.071 13.2 1.1 1.2 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Zn_Tnp_IS1595 PF12760.7 AIO02336.1 - 0.065 13.2 2.3 0.11 12.5 2.3 1.4 1 0 0 1 1 1 0 Transposase zinc-ribbon domain NOB1_Zn_bind PF08772.11 AIO02336.1 - 0.16 12.2 3.8 0.43 10.8 0.6 2.3 1 1 1 2 2 2 0 Nin one binding (NOB1) Zn-ribbon like zf-C3HC4 PF00097.25 AIO02337.1 - 3.2e-10 39.7 5.8 4.9e-10 39.1 5.8 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 AIO02337.1 - 1.1e-09 38.0 3.8 1.5e-09 37.5 3.8 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 AIO02337.1 - 3.8e-09 36.2 7.9 6.2e-09 35.6 7.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 AIO02337.1 - 3.9e-09 36.2 5.1 6.6e-09 35.5 5.1 1.3 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 AIO02337.1 - 5.5e-09 36.2 9.0 8.5e-09 35.6 9.0 1.3 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 AIO02337.1 - 6e-09 35.8 5.5 7.7e-09 35.4 3.4 2.1 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4_4 PF15227.6 AIO02337.1 - 8.5e-08 32.2 6.8 1.4e-07 31.5 6.8 1.4 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 AIO02337.1 - 2.6e-06 27.3 5.2 4.3e-06 26.6 5.2 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.7 AIO02337.1 - 0.0016 18.7 9.8 0.0047 17.2 9.8 1.8 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_6 PF14835.6 AIO02337.1 - 0.0027 17.5 4.3 0.0062 16.4 4.3 1.5 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-ANAPC11 PF12861.7 AIO02337.1 - 0.0033 17.4 1.9 0.0061 16.6 1.9 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger HemY_N PF07219.13 AIO02337.1 - 0.04 14.1 0.0 0.12 12.6 0.0 1.8 1 0 0 1 1 1 0 HemY protein N-terminus Baculo_IE-1 PF05290.11 AIO02337.1 - 0.04 13.9 1.7 0.065 13.2 1.7 1.2 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) zf-RING_10 PF16685.5 AIO02337.1 - 0.073 13.2 3.8 0.12 12.5 3.8 1.3 1 0 0 1 1 1 0 zinc RING finger of MSL2 zf-RING_4 PF14570.6 AIO02337.1 - 0.2 11.5 4.8 0.34 10.7 4.8 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Zn_ribbon_17 PF17120.5 AIO02337.1 - 0.34 10.6 6.1 0.61 9.8 6.1 1.4 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type TFIIA PF03153.13 AIO02337.1 - 0.58 10.1 8.1 1 9.3 8.2 1.2 1 1 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit zf-RING_11 PF17123.5 AIO02337.1 - 1.8 8.4 7.1 0.99 9.2 3.6 2.3 2 1 0 2 2 2 0 RING-like zinc finger IBR PF01485.21 AIO02337.1 - 3 8.1 8.8 8.5 6.7 8.8 1.7 1 1 1 2 2 2 0 IBR domain, a half RING-finger domain Nucleoside_tran PF01733.18 AIO02338.1 - 1.6e-28 100.0 4.9 7.2e-28 97.9 4.9 2.0 1 1 0 1 1 1 1 Nucleoside transporter MutS_V PF00488.21 AIO02339.1 - 2.1e-55 187.7 0.8 3.8e-54 183.6 0.8 2.4 1 1 0 1 1 1 1 MutS domain V MutS_III PF05192.18 AIO02339.1 - 5.9e-33 114.7 0.5 1.2e-32 113.6 0.5 1.6 1 0 0 1 1 1 1 MutS domain III MutS_I PF01624.20 AIO02339.1 - 2.1e-32 111.7 0.1 4.9e-32 110.5 0.1 1.7 1 0 0 1 1 1 1 MutS domain I AAA_29 PF13555.6 AIO02339.1 - 0.011 15.4 0.0 0.033 13.9 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.27 AIO02339.1 - 0.023 15.2 0.0 0.06 13.9 0.0 1.7 1 0 0 1 1 1 0 ABC transporter AAA_23 PF13476.6 AIO02339.1 - 0.097 13.2 0.0 1.7 9.1 0.0 2.2 2 0 0 2 2 2 0 AAA domain TLD PF07534.16 AIO02340.1 - 2.2e-21 76.5 0.3 1.4e-11 44.7 0.4 2.3 2 0 0 2 2 2 2 TLD PMM PF03332.13 AIO02341.1 - 1.2e-99 332.5 1.2 1.4e-99 332.4 1.2 1.0 1 0 0 1 1 1 1 Eukaryotic phosphomannomutase Hydrolase_3 PF08282.12 AIO02341.1 - 6.8e-09 35.8 0.0 2.1e-08 34.2 0.0 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase S6PP PF05116.13 AIO02341.1 - 3e-05 23.7 0.0 0.029 13.9 0.0 2.1 2 0 0 2 2 2 2 Sucrose-6F-phosphate phosphohydrolase FliG_N PF14842.6 AIO02341.1 - 0.012 16.2 0.0 0.028 15.0 0.0 1.6 1 0 0 1 1 1 0 FliG N-terminal domain Hydrolase PF00702.26 AIO02341.1 - 0.082 13.2 0.1 0.14 12.4 0.1 1.6 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 AIO02341.1 - 0.19 11.8 1.3 7.3 6.6 0.0 3.0 2 1 1 3 3 3 0 Haloacid dehalogenase-like hydrolase 2OG-FeII_Oxy_2 PF13532.6 AIO02342.1 - 5.2e-09 36.6 0.0 3.7e-08 33.8 0.0 2.1 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.20 AIO02342.1 - 0.0019 18.6 0.0 0.0034 17.8 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Metallophos PF00149.28 AIO02343.1 - 2.1e-17 64.3 0.0 3e-17 63.8 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase FlxA PF14282.6 AIO02346.1 - 0.011 15.7 8.9 0.011 15.7 8.9 2.8 1 1 1 3 3 3 0 FlxA-like protein ALIX_LYPXL_bnd PF13949.6 AIO02346.1 - 0.067 12.5 19.7 0.1 11.9 19.7 1.2 1 0 0 1 1 1 0 ALIX V-shaped domain binding to HIV Bacillus_HBL PF05791.11 AIO02346.1 - 0.1 12.4 8.4 0.23 11.3 3.5 2.2 2 0 0 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) CSN5_C PF18323.1 AIO02346.1 - 0.3 12.0 10.0 1 10.3 0.1 2.6 2 1 0 2 2 2 0 Cop9 signalosome subunit 5 C-terminal domain TPR_MLP1_2 PF07926.12 AIO02346.1 - 4.4 7.4 39.3 1.2 9.2 10.0 3.3 1 1 2 3 3 3 0 TPR/MLP1/MLP2-like protein 5_nucleotid PF05761.14 AIO02346.1 - 6 5.6 12.8 4.1 6.2 4.0 2.1 2 0 0 2 2 2 0 5' nucleotidase family Stathmin PF00836.19 AIO02346.1 - 6.7 6.7 18.4 0.43 10.5 8.6 2.2 2 0 0 2 2 2 0 Stathmin family ApoO PF09769.9 AIO02346.1 - 7.4 6.6 6.8 2.4 8.1 1.3 2.4 2 0 0 2 2 2 0 Apolipoprotein O TFIIA PF03153.13 AIO02346.1 - 9.5 6.1 15.4 13 5.6 15.4 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Cpn60_TCP1 PF00118.24 AIO02347.1 - 3.4e-84 283.3 16.2 6.8e-84 282.2 16.2 1.4 1 1 0 1 1 1 1 TCP-1/cpn60 chaperonin family WD40 PF00400.32 AIO02348.1 - 8.7e-09 35.9 5.7 0.013 16.4 0.3 5.4 5 0 0 5 5 5 3 WD domain, G-beta repeat ALG3 PF05208.13 AIO02349.1 - 4.5e-122 407.9 14.3 5.5e-122 407.7 14.3 1.0 1 0 0 1 1 1 1 ALG3 protein Metallophos PF00149.28 AIO02350.1 - 4e-17 63.4 0.0 1e-11 45.8 0.0 2.4 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase DUF72 PF01904.18 AIO02351.1 - 2e-29 103.3 0.0 2.3e-26 93.3 0.0 2.1 2 0 0 2 2 2 2 Protein of unknown function DUF72 TPR_2 PF07719.17 AIO02352.1 - 1.6e-12 46.5 6.3 4.6e-06 26.3 0.6 3.7 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.28 AIO02352.1 - 6.7e-09 35.2 5.8 0.00058 19.6 0.1 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.6 AIO02352.1 - 7.3e-08 32.0 1.9 0.037 13.7 0.3 3.9 3 1 1 4 4 4 3 TPR repeat TPR_8 PF13181.6 AIO02352.1 - 1.5e-06 27.9 0.6 0.00061 19.8 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.6 AIO02352.1 - 0.00014 22.1 2.7 0.072 13.4 0.3 2.7 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.6 AIO02352.1 - 0.0028 18.3 1.9 0.0028 18.3 1.9 3.7 2 1 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 AIO02352.1 - 0.0044 17.7 1.6 0.0044 17.7 1.6 3.8 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.6 AIO02352.1 - 0.0052 16.7 0.3 0.072 13.2 0.2 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_9 PF13371.6 AIO02352.1 - 0.034 14.3 5.2 0.52 10.5 1.1 2.8 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.6 AIO02352.1 - 0.26 12.0 1.4 1.2 9.9 0.1 2.9 2 1 0 2 2 2 0 Tetratricopeptide repeat ATXN-1_C PF12547.8 AIO02352.1 - 0.45 10.9 2.3 0.52 10.7 0.1 2.2 3 0 0 3 3 3 0 Capicua transcriptional repressor modulator SPA PF08616.10 AIO02354.1 - 0.0082 16.1 0.0 0.021 14.8 0.0 1.6 1 0 0 1 1 1 1 Stabilization of polarity axis F-actin_cap_A PF01267.17 AIO02354.1 - 0.017 14.5 0.1 0.027 13.9 0.1 1.3 1 0 0 1 1 1 0 F-actin capping protein alpha subunit Acetyltransf_10 PF13673.7 AIO02355.1 - 0.0017 18.3 0.1 0.024 14.6 0.0 2.2 1 1 1 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 AIO02355.1 - 0.009 16.2 0.0 0.06 13.6 0.0 2.3 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family DnaJ PF00226.31 AIO02356.1 - 1.8e-21 76.0 0.5 2.8e-21 75.4 0.5 1.3 1 0 0 1 1 1 1 DnaJ domain DUF1977 PF09320.11 AIO02356.1 - 3.2e-06 27.3 0.6 2.5e-05 24.5 0.0 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF1977) DEAD PF00270.29 AIO02359.1 - 1.6e-48 164.8 0.0 3.1e-48 163.8 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 AIO02359.1 - 8.5e-32 109.8 0.1 3.1e-30 104.8 0.2 2.5 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 AIO02359.1 - 1.6e-05 24.9 0.0 0.0022 18.0 0.0 2.3 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit AAA_30 PF13604.6 AIO02359.1 - 0.00092 19.0 0.0 0.078 12.7 0.0 2.6 2 1 0 2 2 2 1 AAA domain ERCC3_RAD25_C PF16203.5 AIO02359.1 - 0.0026 17.0 0.1 0.0038 16.5 0.1 1.2 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase EMP24_GP25L PF01105.24 AIO02361.1 - 2e-27 96.3 0.5 3.5e-27 95.5 0.5 1.4 1 1 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Dynein_light PF01221.18 AIO02362.1 - 8e-20 71.0 0.0 1e-19 70.6 0.0 1.1 1 0 0 1 1 1 1 Dynein light chain type 1 DUF3646 PF12362.8 AIO02362.1 - 0.0016 18.8 0.0 0.0023 18.2 0.0 1.4 1 1 0 1 1 1 1 DNA polymerase III gamma and tau subunits C terminal Alpha-amyl_C PF09071.10 AIO02362.1 - 0.088 12.7 0.0 0.14 12.1 0.0 1.3 1 0 0 1 1 1 0 Alpha-amylase, C terminal Methyltr_RsmB-F PF01189.17 AIO02363.1 - 9.1e-30 103.8 0.0 4.1e-22 78.8 0.0 3.1 2 1 0 2 2 2 2 16S rRNA methyltransferase RsmB/F FtsJ PF01728.19 AIO02363.1 - 0.01 15.9 0.0 0.026 14.7 0.0 1.6 1 0 0 1 1 1 0 FtsJ-like methyltransferase Y_phosphatase PF00102.27 AIO02364.1 - 3e-44 151.4 0.0 6.5e-44 150.3 0.0 1.7 1 1 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.20 AIO02364.1 - 4.5e-05 23.3 0.1 9.1e-05 22.3 0.1 1.5 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain PRK PF00485.18 AIO02364.1 - 0.11 12.2 0.1 0.19 11.4 0.1 1.3 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family Y_phosphatase3 PF13350.6 AIO02364.1 - 0.14 12.1 0.7 0.32 10.9 0.1 2.0 2 1 0 2 2 2 0 Tyrosine phosphatase family FA PF08736.11 AIO02365.1 - 0.64 10.1 3.6 0.37 10.9 0.3 2.5 2 0 0 2 2 2 0 FERM adjacent (FA) Choline_transpo PF04515.12 AIO02367.1 - 1.1e-64 218.8 32.0 1.1e-64 218.8 32.0 2.6 2 1 0 2 2 2 1 Plasma-membrane choline transporter DUF4234 PF14018.6 AIO02367.1 - 0.019 15.1 9.1 0.84 9.8 0.7 3.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4234) UL41A PF17591.2 AIO02367.1 - 6.7 6.9 6.8 1.4 9.1 1.2 2.7 2 0 0 2 2 2 0 Herpesvirus UL41A BRCT_2 PF16589.5 AIO02368.1 - 1.6e-06 28.4 0.0 0.053 13.9 0.0 2.6 2 0 0 2 2 2 2 BRCT domain, a BRCA1 C-terminus domain BRCT PF00533.26 AIO02368.1 - 0.00017 21.9 0.0 0.11 12.9 0.0 3.3 2 1 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.7 AIO02368.1 - 0.0067 16.4 0.2 3 7.9 0.0 2.9 3 0 0 3 3 3 2 twin BRCT domain BRCT_3 PF18428.1 AIO02368.1 - 0.0092 16.0 0.1 2.2 8.4 0.0 2.4 2 0 0 2 2 2 2 BRCA1 C Terminus (BRCT) domain LIG3_BRCT PF16759.5 AIO02368.1 - 0.15 12.4 0.0 34 4.8 0.0 2.7 2 0 0 2 2 2 0 DNA ligase 3 BRCT domain Sec1 PF00995.23 AIO02369.1 - 8.3e-103 345.6 0.1 1e-102 345.3 0.1 1.0 1 0 0 1 1 1 1 Sec1 family Corona_NSP4_C PF16348.5 AIO02369.1 - 0.12 13.2 1.0 7.2 7.5 0.1 3.4 2 1 1 3 3 3 0 Coronavirus nonstructural protein 4 C-terminus GCP_N_terminal PF17681.1 AIO02370.1 - 6.8e-16 58.8 0.0 3e-15 56.7 0.0 2.0 2 0 0 2 2 2 1 Gamma tubulin complex component N-terminal MMR_HSR1_Xtn PF16897.5 AIO02371.1 - 1.8e-42 143.7 0.0 4e-42 142.6 0.0 1.6 1 0 0 1 1 1 1 C-terminal region of MMR_HSR1 domain MMR_HSR1 PF01926.23 AIO02371.1 - 1.8e-19 69.9 0.0 3.8e-19 68.8 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase TGS PF02824.21 AIO02371.1 - 4.3e-18 65.1 0.0 8.2e-18 64.2 0.0 1.5 1 0 0 1 1 1 1 TGS domain FeoB_N PF02421.18 AIO02371.1 - 4.8e-09 35.9 0.0 1.6e-08 34.2 0.0 1.8 2 0 0 2 2 2 1 Ferrous iron transport protein B MeaB PF03308.16 AIO02371.1 - 0.0037 16.3 0.2 0.0096 14.9 0.1 1.7 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB Dynamin_N PF00350.23 AIO02371.1 - 0.11 12.5 0.2 4.4 7.3 0.0 2.3 1 1 1 2 2 2 0 Dynamin family RsgA_GTPase PF03193.16 AIO02371.1 - 0.22 11.4 1.4 4.2 7.3 0.1 2.9 2 1 1 3 3 3 0 RsgA GTPase Guanylate_kin PF00625.21 AIO02372.1 - 2e-39 135.1 0.0 1e-23 84.0 0.0 3.0 2 1 0 2 2 2 2 Guanylate kinase Rad17 PF03215.15 AIO02372.1 - 2.4e-06 27.6 0.0 3.9e-06 26.9 0.0 1.2 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_33 PF13671.6 AIO02372.1 - 7.6e-05 22.9 0.1 0.0053 16.9 0.1 2.5 1 1 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 AIO02372.1 - 0.00074 19.5 0.0 0.0013 18.7 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase AAA_16 PF13191.6 AIO02372.1 - 0.0021 18.4 0.0 0.0038 17.6 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 AIO02372.1 - 0.014 15.6 0.0 0.12 12.7 0.0 2.2 1 1 0 2 2 2 0 AAA domain ABC_tran PF00005.27 AIO02372.1 - 0.015 15.8 0.0 0.029 14.9 0.0 1.5 1 0 0 1 1 1 0 ABC transporter RNA_helicase PF00910.22 AIO02372.1 - 0.018 15.4 0.0 0.046 14.1 0.0 1.7 1 0 0 1 1 1 0 RNA helicase MMR_HSR1 PF01926.23 AIO02372.1 - 0.029 14.5 0.0 0.075 13.1 0.0 1.8 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_29 PF13555.6 AIO02372.1 - 0.03 14.1 0.0 0.059 13.1 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain NACHT PF05729.12 AIO02372.1 - 0.031 14.2 0.0 0.082 12.8 0.0 1.7 1 0 0 1 1 1 0 NACHT domain Viral_helicase1 PF01443.18 AIO02372.1 - 0.032 14.0 0.0 0.052 13.3 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_5 PF07728.14 AIO02372.1 - 0.033 14.2 0.0 0.18 11.8 0.0 2.0 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 AIO02372.1 - 0.034 14.7 0.0 0.17 12.5 0.0 2.0 2 0 0 2 2 2 0 AAA domain TniB PF05621.11 AIO02372.1 - 0.039 13.4 0.0 0.067 12.6 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein AAA_17 PF13207.6 AIO02372.1 - 0.044 14.2 0.0 0.99 9.8 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 AIO02372.1 - 0.057 13.7 0.0 0.2 11.9 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 AIO02372.1 - 0.066 12.7 0.0 0.12 11.9 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region Mg_chelatase PF01078.21 AIO02372.1 - 0.078 12.4 0.0 0.15 11.4 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI G-alpha PF00503.20 AIO02372.1 - 0.099 11.8 0.0 0.16 11.1 0.0 1.3 1 0 0 1 1 1 0 G-protein alpha subunit DUF3452 PF11934.8 AIO02373.1 - 0.14 11.7 0.0 0.33 10.5 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3452) TPR_1 PF00515.28 AIO02374.1 - 6.3e-30 101.7 6.9 0.00045 19.9 0.2 8.8 8 1 0 8 8 8 6 Tetratricopeptide repeat TPR_8 PF13181.6 AIO02374.1 - 8.3e-26 88.0 2.3 6.8e-05 22.8 0.0 7.9 8 0 0 8 8 7 4 Tetratricopeptide repeat TPR_2 PF07719.17 AIO02374.1 - 1.1e-25 87.6 16.8 0.00029 20.7 0.2 9.7 10 1 0 10 10 9 5 Tetratricopeptide repeat TPR_11 PF13414.6 AIO02374.1 - 2.4e-22 78.4 1.1 7e-07 28.8 0.1 7.1 6 2 1 7 7 7 4 TPR repeat TPR_16 PF13432.6 AIO02374.1 - 9.8e-18 64.5 9.3 0.0035 18.0 0.0 7.0 3 2 5 8 8 8 4 Tetratricopeptide repeat TPR_19 PF14559.6 AIO02374.1 - 2.3e-16 60.1 8.4 2.3e-06 28.0 0.7 5.9 3 2 3 6 6 6 3 Tetratricopeptide repeat TPR_12 PF13424.6 AIO02374.1 - 4.1e-16 59.0 20.6 6.3e-06 26.4 3.0 7.1 2 2 7 9 9 9 6 Tetratricopeptide repeat TPR_14 PF13428.6 AIO02374.1 - 8.9e-16 57.2 11.7 0.0015 19.1 0.0 7.9 4 3 5 9 9 8 4 Tetratricopeptide repeat TPR_17 PF13431.6 AIO02374.1 - 9.3e-16 57.0 8.1 0.00026 21.2 0.0 8.6 9 0 0 9 9 9 2 Tetratricopeptide repeat TPR_9 PF13371.6 AIO02374.1 - 2.2e-12 46.9 9.4 3.2e-06 27.2 0.2 4.9 3 1 2 6 6 6 4 Tetratricopeptide repeat TPR_7 PF13176.6 AIO02374.1 - 1e-10 40.9 8.6 0.027 14.5 0.0 6.6 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_6 PF13174.6 AIO02374.1 - 1.2e-10 41.3 10.7 1.8 9.4 0.7 8.3 8 0 0 8 8 8 2 Tetratricopeptide repeat ANAPC3 PF12895.7 AIO02374.1 - 1.2e-09 38.2 18.1 0.0042 17.3 0.0 5.6 3 3 3 6 6 6 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_10 PF13374.6 AIO02374.1 - 2.1e-07 30.6 12.4 0.0066 16.3 0.2 6.4 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_20 PF14561.6 AIO02374.1 - 4.7e-06 26.8 3.0 0.24 11.7 0.1 4.4 3 1 2 5 5 5 2 Tetratricopeptide repeat ChAPs PF09295.10 AIO02374.1 - 8.7e-05 21.7 0.5 0.021 13.8 0.0 3.3 1 1 2 4 4 4 1 ChAPs (Chs5p-Arf1p-binding proteins) TPR_4 PF07721.14 AIO02374.1 - 9.5e-05 22.7 13.9 0.0076 16.8 1.3 4.4 3 0 0 3 3 3 1 Tetratricopeptide repeat BTAD PF03704.17 AIO02374.1 - 0.00045 20.7 6.8 0.044 14.2 0.1 4.0 3 1 1 4 4 4 1 Bacterial transcriptional activator domain NARP1 PF12569.8 AIO02374.1 - 0.001 18.1 0.7 8.4 5.2 0.1 3.4 2 1 2 4 4 4 0 NMDA receptor-regulated protein 1 PknG_TPR PF16918.5 AIO02374.1 - 0.0013 17.5 0.2 0.0059 15.4 0.0 2.0 2 0 0 2 2 2 1 Protein kinase G tetratricopeptide repeat DUF3808 PF10300.9 AIO02374.1 - 0.0065 15.3 0.3 0.0099 14.7 0.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3808) NatB_MDM20 PF09797.9 AIO02374.1 - 0.0079 15.2 1.8 0.44 9.4 0.2 2.2 2 0 0 2 2 2 1 N-acetyltransferase B complex (NatB) non catalytic subunit Paf67 PF10255.9 AIO02374.1 - 0.0086 15.1 0.7 0.22 10.5 0.3 2.5 2 1 0 2 2 2 1 RNA polymerase I-associated factor PAF67 Alkyl_sulf_dimr PF14863.6 AIO02374.1 - 0.013 15.9 0.4 21 5.6 0.0 3.4 3 0 0 3 3 3 0 Alkyl sulfatase dimerisation Wzy_C_2 PF11846.8 AIO02374.1 - 0.014 15.3 4.4 1.3 8.9 0.2 2.8 3 0 0 3 3 2 0 Virulence factor membrane-bound polymerase, C-terminal dNK PF01712.19 AIO02374.1 - 0.16 11.8 0.1 0.39 10.5 0.1 1.6 1 0 0 1 1 1 0 Deoxynucleoside kinase DUF3856 PF12968.7 AIO02374.1 - 1.9 8.6 4.0 12 6.0 0.0 3.5 5 0 0 5 5 4 0 Domain of Unknown Function (DUF3856) Ribosomal_S18 PF01084.20 AIO02376.1 - 0.0001 22.4 0.0 0.00025 21.2 0.0 1.7 1 0 0 1 1 1 1 Ribosomal protein S18 Glucokinase PF02685.16 AIO02377.1 - 4e-15 55.6 0.0 1.8e-14 53.4 0.0 2.0 1 1 0 1 1 1 1 Glucokinase Endonuclease_5 PF04493.14 AIO02378.1 - 1.2e-54 185.1 0.0 1.6e-54 184.6 0.0 1.1 1 0 0 1 1 1 1 Endonuclease V adh_short PF00106.25 AIO02379.1 - 2.2e-14 53.4 1.4 1.2e-06 28.1 0.2 2.8 1 1 1 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 AIO02379.1 - 2.6e-08 33.7 0.2 5.8e-06 26.0 0.1 2.4 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 AIO02379.1 - 3e-06 27.3 1.6 6.2e-06 26.2 1.6 1.6 1 1 0 1 1 1 1 KR domain NAD_binding_2 PF03446.15 AIO02379.1 - 0.0082 16.3 0.1 0.021 15.0 0.1 1.7 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase Epimerase PF01370.21 AIO02379.1 - 0.01 15.3 0.2 0.03 13.8 0.2 1.8 1 1 1 2 2 2 0 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 AIO02379.1 - 0.064 12.4 0.0 0.29 10.2 0.0 1.8 1 1 0 1 1 1 0 Polysaccharide biosynthesis protein 2-Hacid_dh_C PF02826.19 AIO02379.1 - 0.15 11.4 0.0 0.3 10.4 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Aminotran_1_2 PF00155.21 AIO02380.1 - 2.2e-60 204.7 0.0 2.9e-60 204.4 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 AIO02380.1 - 0.0015 17.2 0.0 0.0024 16.5 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Beta_elim_lyase PF01212.21 AIO02380.1 - 0.085 12.1 0.0 0.13 11.5 0.0 1.3 1 0 0 1 1 1 0 Beta-eliminating lyase PRIMA1 PF16101.5 AIO02381.1 - 2.2 8.4 22.2 0.46 10.5 0.3 4.3 4 0 0 4 4 4 0 Proline-rich membrane anchor 1 Sterol_MT_C PF08498.10 AIO02382.1 - 2.5e-22 78.9 0.1 5.1e-22 78.0 0.1 1.5 1 0 0 1 1 1 1 Sterol methyltransferase C-terminal Methyltransf_11 PF08241.12 AIO02382.1 - 2.8e-17 63.2 0.3 9.7e-17 61.4 0.0 2.0 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_25 PF13649.6 AIO02382.1 - 1.2e-14 54.7 0.1 7e-14 52.3 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 AIO02382.1 - 5.8e-12 45.6 0.0 1.4e-11 44.4 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 AIO02382.1 - 9.2e-09 35.3 0.0 1.9e-08 34.3 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 AIO02382.1 - 5.9e-08 33.4 0.1 2.4e-06 28.2 0.0 2.8 3 0 0 3 3 3 1 Methyltransferase domain Ubie_methyltran PF01209.18 AIO02382.1 - 2.7e-07 30.2 0.0 4.6e-07 29.4 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family CMAS PF02353.20 AIO02382.1 - 5.8e-07 29.1 0.2 9.7e-07 28.3 0.2 1.3 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_15 PF09445.10 AIO02382.1 - 0.038 13.6 0.4 0.06 12.9 0.4 1.3 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase MTS PF05175.14 AIO02382.1 - 0.042 13.4 0.0 0.75 9.3 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase small domain UPF0020 PF01170.18 AIO02382.1 - 0.065 12.9 0.0 0.13 11.9 0.0 1.5 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 EF-hand_7 PF13499.6 AIO02383.1 - 0.0005 20.5 0.0 0.00097 19.6 0.0 1.4 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.6 AIO02383.1 - 0.0076 16.1 0.0 6.5 7.0 0.0 2.5 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.32 AIO02383.1 - 0.01 15.3 0.0 3.4 7.5 0.0 2.4 2 0 0 2 2 2 0 EF hand RAG2_PHD PF13341.6 AIO02383.1 - 0.022 14.8 0.0 0.043 13.9 0.0 1.5 1 0 0 1 1 1 0 RAG2 PHD domain Cullin_Nedd8 PF10557.9 AIO02384.1 - 1.3e-15 57.1 0.3 2.4e-15 56.3 0.3 1.5 1 0 0 1 1 1 1 Cullin protein neddylation domain Peptidase_S9 PF00326.21 AIO02385.1 - 5.8e-33 114.2 0.1 1.3e-32 113.0 0.1 1.6 2 0 0 2 2 2 1 Prolyl oligopeptidase family DPPIV_N PF00930.21 AIO02385.1 - 5e-25 88.0 0.0 8.8e-25 87.2 0.0 1.3 1 0 0 1 1 1 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Abhydrolase_6 PF12697.7 AIO02385.1 - 0.02 15.5 0.3 0.061 13.9 0.1 1.9 1 1 0 1 1 1 0 Alpha/beta hydrolase family Peptidase_S15 PF02129.18 AIO02385.1 - 0.098 12.2 0.1 0.49 9.9 0.1 2.0 2 0 0 2 2 2 0 X-Pro dipeptidyl-peptidase (S15 family) Syntaxin PF00804.25 AIO02386.1 - 0.053 13.2 0.2 5.4 6.6 0.1 2.2 2 0 0 2 2 2 0 Syntaxin FYVE PF01363.21 AIO02387.1 - 0.00041 20.4 6.1 0.00041 20.4 6.1 1.8 2 0 0 2 2 2 1 FYVE zinc finger zf-B_box PF00643.24 AIO02387.1 - 0.24 11.6 5.2 1.3 9.2 2.0 2.3 2 0 0 2 2 2 0 B-box zinc finger SVIP PF15811.5 AIO02387.1 - 0.44 11.0 6.3 0.41 11.1 0.3 2.3 2 0 0 2 2 2 0 Small VCP/p97-interacting protein FYVE_2 PF02318.16 AIO02387.1 - 5.9 7.1 6.6 26 5.1 6.6 2.0 1 1 0 1 1 1 0 FYVE-type zinc finger His_Phos_2 PF00328.22 AIO02390.1 - 3.3e-12 46.5 0.3 1.1e-06 28.3 0.1 3.1 2 1 0 2 2 2 2 Histidine phosphatase superfamily (branch 2) RRM_1 PF00076.22 AIO02391.1 - 0.17 11.7 0.0 0.39 10.6 0.0 1.7 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) WD40 PF00400.32 AIO02393.1 - 2.2e-18 66.3 13.0 8.7e-07 29.6 1.0 5.8 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 AIO02393.1 - 1.8e-09 37.8 0.7 4.6 7.6 0.0 5.4 5 0 0 5 5 5 5 Anaphase-promoting complex subunit 4 WD40 domain Nic96 PF04097.14 AIO02394.1 - 1.7e-62 211.8 0.2 2.7e-62 211.1 0.2 1.3 1 0 0 1 1 1 1 Nup93/Nic96 UTP15_C PF09384.10 AIO02394.1 - 0.063 13.0 0.1 1.2 8.8 0.0 3.0 3 0 0 3 3 3 0 UTP15 C terminal Slx4 PF09494.10 AIO02394.1 - 0.07 13.1 0.0 0.19 11.7 0.0 1.7 1 0 0 1 1 1 0 Slx4 endonuclease SNAPc_SNAP43 PF09808.9 AIO02395.1 - 0.00084 19.3 0.0 0.0013 18.7 0.0 1.3 1 0 0 1 1 1 1 Small nuclear RNA activating complex (SNAPc), subunit SNAP43 DEAD PF00270.29 AIO02396.1 - 8.3e-25 87.6 0.0 1.3e-23 83.7 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 AIO02396.1 - 2.5e-24 85.8 0.0 1.1e-21 77.2 0.0 2.4 2 0 0 2 2 2 2 Helicase conserved C-terminal domain ResIII PF04851.15 AIO02396.1 - 0.0034 17.4 0.0 0.062 13.3 0.0 2.3 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 AIO02396.1 - 0.0059 16.9 0.0 2.8 8.2 0.0 2.7 1 1 1 2 2 2 2 AAA domain Helicase_C_2 PF13307.6 AIO02396.1 - 0.022 14.9 0.0 0.9 9.7 0.0 2.4 2 0 0 2 2 2 0 Helicase C-terminal domain NUC130_3NT PF08158.12 AIO02396.1 - 0.12 12.8 0.0 0.39 11.1 0.0 1.9 1 0 0 1 1 1 0 NUC130/3NT domain FA_hydroxylase PF04116.13 AIO02397.1 - 6.7e-21 75.0 16.3 6.7e-21 75.0 16.3 2.6 3 0 0 3 3 3 1 Fatty acid hydroxylase superfamily DUF570 PF04489.13 AIO02397.1 - 0.032 12.9 0.1 0.055 12.1 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF570) His_Phos_2 PF00328.22 AIO02398.1 - 1.4e-11 44.3 0.1 1.9e-07 30.8 0.0 3.0 2 1 0 2 2 2 2 Histidine phosphatase superfamily (branch 2) HEAT PF02985.22 AIO02399.1 - 0.00063 19.8 2.4 3.5 8.1 0.1 4.5 3 0 0 3 3 3 2 HEAT repeat GDPD PF03009.17 AIO02401.1 - 5.1e-37 128.0 0.0 7.3e-37 127.5 0.0 1.2 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family LPAM_2 PF13627.6 AIO02401.1 - 0.12 12.3 0.1 0.29 11.0 0.1 1.7 1 0 0 1 1 1 0 Prokaryotic lipoprotein-attachment site His_Phos_2 PF00328.22 AIO02402.1 - 3.2e-08 33.3 0.4 3e-05 23.6 0.0 3.1 1 1 1 2 2 2 2 Histidine phosphatase superfamily (branch 2) RCC1_2 PF13540.6 AIO02403.1 - 6.9e-20 70.3 15.1 4.6e-06 26.3 0.1 3.7 3 0 0 3 3 3 3 Regulator of chromosome condensation (RCC1) repeat RCC1 PF00415.18 AIO02403.1 - 3.4e-19 69.2 9.3 0.00019 22.0 0.1 5.9 5 0 0 5 5 5 4 Regulator of chromosome condensation (RCC1) repeat DUF4213 PF13938.6 AIO02403.1 - 0.16 12.2 4.6 14 6.0 0.1 3.7 3 1 0 3 3 3 0 Putative heavy-metal chelation Mur_ligase_M PF08245.12 AIO02404.1 - 1.2e-10 41.7 0.1 4.2e-10 40.0 0.1 1.9 1 1 0 1 1 1 1 Mur ligase middle domain Sulfatase PF00884.23 AIO02404.1 - 0.17 11.2 0.0 0.91 8.8 0.0 1.6 1 1 0 2 2 2 0 Sulfatase VRR_NUC PF08774.11 AIO02405.1 - 9.1e-08 32.1 0.0 2.1e-07 30.9 0.0 1.6 1 0 0 1 1 1 1 VRR-NUC domain TPR_2 PF07719.17 AIO02405.1 - 0.28 11.4 0.8 1.2 9.5 0.8 2.2 1 0 0 1 1 1 0 Tetratricopeptide repeat Pkinase PF00069.25 AIO02406.1 - 2.1e-23 83.0 0.0 3.1e-13 49.7 0.0 3.3 3 1 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 AIO02406.1 - 1.2e-11 44.4 0.0 3.8e-10 39.5 0.0 2.6 2 0 0 2 2 2 1 Protein tyrosine kinase PCI PF01399.27 AIO02407.1 - 5.6e-05 23.6 0.0 0.091 13.3 0.0 3.2 3 0 0 3 3 3 2 PCI domain Methyltransf_11 PF08241.12 AIO02408.1 - 5.7e-11 42.9 0.0 4.4e-08 33.7 0.0 3.2 1 1 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 AIO02408.1 - 1.5e-10 41.6 0.0 0.00012 22.7 0.0 3.8 3 1 1 4 4 4 3 Methyltransferase domain Methyltransf_23 PF13489.6 AIO02408.1 - 6.8e-05 22.8 0.0 0.00011 22.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 AIO02408.1 - 7.8e-05 23.4 0.0 0.00056 20.6 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 AIO02408.1 - 0.0001 22.1 0.0 0.44 10.3 0.0 3.1 3 0 0 3 3 3 2 Methyltransferase domain 2-oxoacid_dh PF00198.23 AIO02409.1 - 5.4e-76 255.1 0.0 7.1e-76 254.7 0.0 1.1 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) E3_binding PF02817.17 AIO02409.1 - 2.8e-12 46.8 0.3 8.4e-12 45.2 0.3 1.9 1 0 0 1 1 1 1 e3 binding domain Biotin_lipoyl PF00364.22 AIO02409.1 - 3.7e-10 39.5 0.0 2.1e-09 37.1 0.0 2.3 2 0 0 2 2 2 1 Biotin-requiring enzyme Metallophos_2 PF12850.7 AIO02410.1 - 1.6e-07 31.7 0.4 0.0013 18.9 0.0 2.2 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.28 AIO02410.1 - 1.4e-05 25.7 0.0 3.7e-05 24.3 0.0 1.7 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase MMS22L_C PF14911.6 AIO02411.1 - 0.023 13.8 0.0 0.057 12.5 0.0 1.6 1 0 0 1 1 1 0 S-phase genomic integrity recombination mediator, C-terminal Pentapeptide_4 PF13599.6 AIO02412.1 - 2.3e-15 56.5 18.9 1.2e-08 35.0 7.1 2.7 2 1 1 3 3 3 2 Pentapeptide repeats (9 copies) Pentapeptide PF00805.22 AIO02412.1 - 8.6e-12 44.5 11.6 4.5e-06 26.2 1.3 4.2 1 1 1 3 3 3 3 Pentapeptide repeats (8 copies) Pentapeptide_3 PF13576.6 AIO02412.1 - 1.1e-10 41.5 7.7 9.2e-06 25.7 0.4 3.6 1 1 1 3 3 3 3 Pentapeptide repeats (9 copies) T3SSipB PF16535.5 AIO02413.1 - 0.16 12.5 8.5 2.8 8.4 0.1 2.2 2 0 0 2 2 2 0 Type III cell invasion protein SipB Exonuc_VIII PF06630.11 AIO02413.1 - 0.18 11.6 0.6 0.39 10.6 0.1 1.8 2 0 0 2 2 2 0 Enterobacterial exodeoxyribonuclease VIII DUF648 PF04890.13 AIO02413.1 - 0.24 11.1 1.2 0.42 10.3 0.5 1.6 1 1 1 2 2 2 0 Family of unknown function (DUF648) Atg14 PF10186.9 AIO02413.1 - 1.2 8.1 10.2 0.64 9.0 2.6 2.1 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 STAG PF08514.11 AIO02413.1 - 1.5 8.8 5.4 3.4 7.6 0.3 2.5 2 0 0 2 2 2 0 STAG domain Fzo_mitofusin PF04799.13 AIO02413.1 - 3.1 7.3 10.4 6.4 6.3 2.1 2.4 2 0 0 2 2 2 0 fzo-like conserved region Peptidase_M41 PF01434.18 AIO02415.1 - 7.2e-55 185.8 0.0 1.1e-54 185.2 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.29 AIO02415.1 - 3.5e-41 140.7 0.0 6.5e-41 139.9 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 AIO02415.1 - 1.6e-06 27.8 0.9 5.7e-06 26.0 0.1 2.2 2 0 0 2 2 2 1 AAA+ lid domain AAA_5 PF07728.14 AIO02415.1 - 1.7e-05 24.9 0.0 4.4e-05 23.5 0.0 1.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 AIO02415.1 - 2.1e-05 25.0 0.1 0.00016 22.1 0.1 2.2 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 AIO02415.1 - 3.2e-05 24.2 0.6 0.0021 18.3 0.6 2.8 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.12 AIO02415.1 - 0.0001 22.1 0.0 0.00034 20.4 0.0 1.8 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_25 PF13481.6 AIO02415.1 - 0.00024 20.8 0.6 0.068 12.7 0.2 2.4 1 1 1 2 2 2 1 AAA domain AAA_14 PF13173.6 AIO02415.1 - 0.00045 20.2 0.0 0.0016 18.5 0.0 1.9 2 0 0 2 2 2 1 AAA domain TIP49 PF06068.13 AIO02415.1 - 0.0013 18.1 0.0 0.0029 16.9 0.0 1.5 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_18 PF13238.6 AIO02415.1 - 0.0013 19.2 0.0 0.0032 18.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain Rad17 PF03215.15 AIO02415.1 - 0.0027 17.7 0.0 0.0057 16.6 0.0 1.5 1 0 0 1 1 1 1 Rad17 P-loop domain IstB_IS21 PF01695.17 AIO02415.1 - 0.0032 17.2 0.0 0.0077 16.0 0.0 1.7 1 0 0 1 1 1 1 IstB-like ATP binding protein NACHT PF05729.12 AIO02415.1 - 0.0033 17.4 0.5 0.017 15.1 0.1 2.2 2 1 0 3 3 2 1 NACHT domain AAA_17 PF13207.6 AIO02415.1 - 0.0045 17.4 0.0 0.0095 16.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 AIO02415.1 - 0.0046 16.4 0.2 0.012 15.0 0.2 1.6 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_28 PF13521.6 AIO02415.1 - 0.015 15.5 0.0 0.046 14.0 0.0 1.8 2 0 0 2 2 1 0 AAA domain AAA_2 PF07724.14 AIO02415.1 - 0.022 14.8 0.0 0.081 13.0 0.0 2.0 1 1 0 1 1 1 0 AAA domain (Cdc48 subfamily) TsaE PF02367.17 AIO02415.1 - 0.024 14.6 0.0 0.048 13.7 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_33 PF13671.6 AIO02415.1 - 0.033 14.3 0.0 0.071 13.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 AIO02415.1 - 0.034 14.5 0.1 0.12 12.7 0.0 1.9 2 0 0 2 2 2 0 RNA helicase Zeta_toxin PF06414.12 AIO02415.1 - 0.069 12.4 0.1 0.14 11.4 0.1 1.4 1 0 0 1 1 1 0 Zeta toxin ABC_tran PF00005.27 AIO02415.1 - 0.082 13.4 0.6 0.35 11.4 0.3 2.2 2 0 0 2 2 2 0 ABC transporter ATPase PF06745.13 AIO02415.1 - 0.11 11.8 0.1 0.83 8.9 0.0 2.4 3 0 0 3 3 3 0 KaiC TniB PF05621.11 AIO02415.1 - 0.15 11.4 0.0 4.3 6.7 0.0 2.5 2 0 0 2 2 2 0 Bacterial TniB protein DUF815 PF05673.13 AIO02415.1 - 0.16 11.1 0.0 0.38 9.9 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Parvo_NS1 PF01057.17 AIO02415.1 - 0.26 10.3 0.0 0.46 9.5 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Peptidase_M50B PF13398.6 AIO02415.1 - 0.29 10.8 0.6 0.44 10.2 0.0 1.5 2 0 0 2 2 1 0 Peptidase M50B-like RIX1 PF08167.12 AIO02416.1 - 1e-05 25.4 1.3 4.5e-05 23.3 1.3 2.2 1 0 0 1 1 1 1 rRNA processing/ribosome biogenesis HEAT_EZ PF13513.6 AIO02416.1 - 0.00017 22.0 1.7 0.2 12.2 0.0 4.5 3 1 1 4 4 4 2 HEAT-like repeat IBN_N PF03810.19 AIO02416.1 - 0.0005 19.9 0.1 0.015 15.2 0.1 3.1 1 1 0 1 1 1 1 Importin-beta N-terminal domain B56 PF01603.20 AIO02416.1 - 0.1 11.6 0.0 0.19 10.7 0.0 1.3 1 0 0 1 1 1 0 Protein phosphatase 2A regulatory B subunit (B56 family) Tyr_Deacylase PF02580.16 AIO02417.1 - 3.3e-43 147.7 0.0 3.6e-43 147.5 0.0 1.0 1 0 0 1 1 1 1 D-Tyr-tRNA(Tyr) deacylase Acetyltransf_1 PF00583.25 AIO02419.1 - 2.5e-16 59.9 0.1 3.4e-16 59.5 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 AIO02419.1 - 1.2e-05 25.6 0.0 1.6e-05 25.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 AIO02419.1 - 0.0001 22.2 0.0 0.00016 21.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 AIO02419.1 - 0.0057 16.8 0.0 0.0098 16.0 0.0 1.3 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_6 PF13480.7 AIO02419.1 - 0.0082 16.3 0.8 0.025 14.7 0.8 1.9 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 AIO02419.1 - 0.011 15.7 0.0 0.031 14.2 0.0 1.7 2 0 0 2 2 2 0 FR47-like protein DUF3161 PF11362.8 AIO02419.1 - 0.012 15.5 0.0 0.018 15.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3161) Acetyltransf_16 PF05301.11 AIO02419.1 - 0.12 12.2 0.1 0.18 11.6 0.1 1.3 1 0 0 1 1 1 0 GNAT acetyltransferase, Mec-17 MFS_1 PF07690.16 AIO02420.1 - 9.5e-12 44.5 46.5 1e-10 41.1 28.5 2.9 2 1 0 2 2 2 2 Major Facilitator Superfamily Nodulin-like PF06813.13 AIO02420.1 - 5.2e-10 39.2 10.9 5.2e-10 39.2 10.9 2.4 2 0 0 2 2 2 1 Nodulin-like Saf_2TM PF18303.1 AIO02420.1 - 0.095 12.3 4.1 1.2 8.8 0.7 3.0 2 0 0 2 2 2 0 SAVED-fused 2TM effector domain WTF PF03303.13 AIO02420.1 - 7.7 6.2 8.6 0.54 9.9 3.3 1.7 2 0 0 2 2 2 0 WTF protein TP6A_N PF04406.14 AIO02422.1 - 0.00044 20.2 0.0 0.011 15.7 0.0 2.3 2 0 0 2 2 2 1 Type IIB DNA topoisomerase NDK PF00334.19 AIO02423.1 - 0.001 19.1 0.0 0.029 14.4 0.0 2.9 3 0 0 3 3 3 1 Nucleoside diphosphate kinase HA2 PF04408.23 AIO02427.1 - 2e-17 63.4 0.0 2e-17 63.4 0.0 2.7 3 0 0 3 3 3 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 AIO02427.1 - 4.7e-17 62.1 0.0 2.7e-16 59.7 0.0 2.2 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 AIO02427.1 - 6.2e-15 55.5 0.0 1.6e-14 54.2 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 AIO02427.1 - 2.1e-08 34.1 0.6 1.6e-07 31.3 0.1 2.5 3 0 0 3 3 3 1 DEAD/DEAH box helicase AAA_22 PF13401.6 AIO02427.1 - 2.1e-05 24.8 0.6 0.00013 22.2 0.1 2.6 2 1 0 2 2 2 1 AAA domain AAA_30 PF13604.6 AIO02427.1 - 0.0002 21.1 0.7 0.00064 19.5 0.1 2.1 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.17 AIO02427.1 - 0.0084 15.9 0.1 1.3 8.8 0.0 2.6 2 0 0 2 2 2 1 IstB-like ATP binding protein Flavi_DEAD PF07652.14 AIO02427.1 - 0.072 13.1 0.0 0.17 11.9 0.0 1.6 1 0 0 1 1 1 0 Flavivirus DEAD domain AAA_19 PF13245.6 AIO02427.1 - 0.076 13.3 0.1 0.21 11.9 0.1 1.8 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 AIO02427.1 - 0.076 13.5 0.2 1.1 9.8 0.2 2.8 1 1 0 1 1 1 0 ABC transporter AAA_7 PF12775.7 AIO02427.1 - 0.11 12.0 0.0 0.34 10.4 0.0 1.8 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_23 PF13476.6 AIO02427.1 - 0.12 12.9 0.0 0.12 12.9 0.0 2.7 3 1 1 4 4 2 0 AAA domain Hemerythrin PF01814.23 AIO02429.1 - 0.0023 18.6 0.3 0.0026 18.4 0.3 1.0 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain TACC_C PF05010.14 AIO02429.1 - 0.0037 17.1 3.1 0.004 17.0 3.1 1.1 1 0 0 1 1 1 1 Transforming acidic coiled-coil-containing protein (TACC), C-terminal RasGAP_C PF03836.15 AIO02429.1 - 0.0037 17.4 1.2 0.0042 17.2 1.2 1.1 1 0 0 1 1 1 1 RasGAP C-terminus OmpH PF03938.14 AIO02429.1 - 0.0058 17.0 4.9 0.0061 16.9 4.9 1.1 1 0 0 1 1 1 1 Outer membrane protein (OmpH-like) CCDC154 PF15450.6 AIO02429.1 - 0.012 14.2 3.2 0.012 14.2 3.2 1.0 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 154 Spc7 PF08317.11 AIO02429.1 - 0.014 14.3 5.1 0.015 14.2 5.1 1.0 1 0 0 1 1 1 0 Spc7 kinetochore protein APG6_N PF17675.1 AIO02429.1 - 0.021 15.3 7.5 0.026 15.1 7.5 1.2 1 0 0 1 1 1 0 Apg6 coiled-coil region ATG16 PF08614.11 AIO02429.1 - 0.022 15.0 6.5 0.024 14.8 6.5 1.1 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) DUF4407 PF14362.6 AIO02429.1 - 0.024 14.0 3.4 0.029 13.7 3.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF2968 PF11180.8 AIO02429.1 - 0.025 14.2 3.8 0.03 13.9 3.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) UPF0242 PF06785.11 AIO02429.1 - 0.026 14.7 3.8 0.025 14.7 3.8 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus GvpG PF05120.12 AIO02429.1 - 0.031 14.3 5.9 0.045 13.8 5.9 1.4 1 1 0 1 1 1 0 Gas vesicle protein G YabA PF06156.13 AIO02429.1 - 0.041 14.5 3.0 0.084 13.5 3.0 1.5 1 1 0 1 1 1 0 Initiation control protein YabA KxDL PF10241.9 AIO02429.1 - 0.056 13.7 2.5 0.079 13.3 1.9 1.6 1 1 0 1 1 1 0 Uncharacterized conserved protein Baculo_PEP_C PF04513.12 AIO02429.1 - 0.057 13.5 0.4 0.067 13.2 0.4 1.2 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus ILVD_EDD PF00920.21 AIO02429.1 - 0.084 11.5 0.1 0.089 11.4 0.1 1.1 1 0 0 1 1 1 0 Dehydratase family Cob_adeno_trans PF01923.18 AIO02429.1 - 0.097 12.8 0.8 0.11 12.7 0.8 1.1 1 0 0 1 1 1 0 Cobalamin adenosyltransferase RmuC PF02646.16 AIO02429.1 - 0.11 11.6 3.0 0.13 11.4 3.0 1.1 1 0 0 1 1 1 0 RmuC family DUF484 PF04340.12 AIO02429.1 - 0.13 12.0 2.7 0.14 11.8 2.7 1.1 1 0 0 1 1 1 0 Protein of unknown function, DUF484 HAUS6_N PF14661.6 AIO02429.1 - 0.15 11.6 3.2 0.18 11.4 3.2 1.0 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus FUSC PF04632.12 AIO02429.1 - 0.23 10.0 1.1 0.23 9.9 1.1 1.0 1 0 0 1 1 1 0 Fusaric acid resistance protein family Herpes_UL25 PF01499.16 AIO02429.1 - 0.27 9.7 1.6 0.31 9.5 1.6 1.0 1 0 0 1 1 1 0 Herpesvirus UL25 family V_ATPase_I PF01496.19 AIO02429.1 - 0.33 8.8 1.9 0.35 8.7 1.9 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family TMF_DNA_bd PF12329.8 AIO02429.1 - 0.37 10.8 8.7 0.74 9.9 8.7 1.5 1 1 0 1 1 1 0 TATA element modulatory factor 1 DNA binding LCD1 PF09798.9 AIO02429.1 - 0.38 9.2 3.7 0.44 9.0 3.7 1.0 1 0 0 1 1 1 0 DNA damage checkpoint protein ZapB PF06005.12 AIO02429.1 - 0.41 11.1 10.4 4.5 7.8 10.4 2.0 1 1 0 1 1 1 0 Cell division protein ZapB GIT_CC PF16559.5 AIO02429.1 - 0.51 10.3 5.5 4.5 7.2 3.2 2.1 1 1 1 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor TEX13 PF15186.6 AIO02429.1 - 0.74 9.5 5.6 0.94 9.2 5.6 1.1 1 0 0 1 1 1 0 Testis-expressed sequence 13 protein family Spc24 PF08286.11 AIO02429.1 - 1.4 9.2 6.1 1.9 8.8 6.1 1.4 1 1 0 1 1 1 0 Spc24 subunit of Ndc80 DivIC PF04977.15 AIO02429.1 - 1.4 8.7 10.3 5 7.0 1.2 2.2 1 1 1 2 2 2 0 Septum formation initiator DUF4140 PF13600.6 AIO02429.1 - 1.6 9.2 6.1 2.6 8.5 6.1 1.3 1 0 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) CENP-Q PF13094.6 AIO02429.1 - 3.4 7.8 9.8 5.1 7.3 9.8 1.4 1 1 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit Lactamase_B_2 PF12706.7 AIO02430.1 - 0.098 12.2 0.0 0.12 11.9 0.0 1.2 1 0 0 1 1 1 0 Beta-lactamase superfamily domain Ribosomal_S24e PF01282.19 AIO02431.1 - 1.9e-27 95.0 0.0 3.7e-27 94.1 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein S24e ASH PF15780.5 AIO02432.1 - 5.4e-22 77.8 0.2 5e-05 23.4 0.0 9.1 10 0 0 10 10 10 4 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin Motile_Sperm PF00635.26 AIO02432.1 - 1.1e-11 44.5 0.0 0.0052 16.6 0.0 6.5 7 0 0 7 7 7 2 MSP (Major sperm protein) domain TMEM131_like PF12371.8 AIO02432.1 - 0.001 19.3 0.1 1.7 8.9 0.0 4.5 5 0 0 5 5 5 1 Transmembrane protein 131-like DUF1573 PF07610.11 AIO02432.1 - 0.023 14.7 0.0 17 5.5 0.0 4.6 6 0 0 6 6 6 0 Protein of unknown function (DUF1573) MYCBPAP PF14646.6 AIO02432.1 - 0.066 12.2 0.0 23 3.7 0.0 3.3 3 0 0 3 3 3 0 MYCBP-associated protein family ABC2_membrane PF01061.24 AIO02433.1 - 3.2e-37 128.0 18.5 3.2e-37 128.0 18.5 1.6 2 0 0 2 2 1 1 ABC-2 type transporter ABC_tran PF00005.27 AIO02433.1 - 9.6e-24 84.5 0.0 1.6e-23 83.7 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 AIO02433.1 - 2.4e-07 30.9 1.0 0.0062 16.4 0.0 2.2 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system ABC2_membrane_3 PF12698.7 AIO02433.1 - 4.7e-06 25.9 22.4 1.3e-05 24.5 22.4 1.8 1 1 0 1 1 1 1 ABC-2 family transporter protein SMC_N PF02463.19 AIO02433.1 - 0.00076 19.0 0.0 0.01 15.3 0.0 2.1 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 AIO02433.1 - 0.003 17.3 0.0 0.0083 15.8 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 AIO02433.1 - 0.0063 16.4 0.2 0.018 14.9 0.1 1.7 2 0 0 2 2 2 1 RsgA GTPase AAA_16 PF13191.6 AIO02433.1 - 0.0068 16.8 1.7 0.0072 16.7 0.1 1.9 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 AIO02433.1 - 0.0078 16.5 0.1 0.053 13.8 0.1 2.3 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.6 AIO02433.1 - 0.023 15.2 0.0 0.054 14.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 AIO02433.1 - 0.08 13.2 0.2 0.21 11.8 0.2 1.7 1 0 0 1 1 1 0 AAA domain Rad17 PF03215.15 AIO02433.1 - 0.11 12.4 0.0 0.21 11.5 0.0 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_33 PF13671.6 AIO02433.1 - 0.14 12.3 0.9 0.66 10.1 0.1 2.3 2 1 0 2 2 2 0 AAA domain AAA_23 PF13476.6 AIO02433.1 - 0.14 12.6 0.0 0.25 11.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 AIO02433.1 - 0.18 11.5 2.4 0.26 11.0 0.3 2.1 2 0 0 2 2 2 0 AAA domain Pox_A9 PF04835.12 AIO02433.1 - 0.8 9.9 3.7 0.5 10.6 0.4 2.4 2 0 0 2 2 2 0 A9 protein conserved region MCM PF00493.23 AIO02434.1 - 2.3e-05 23.6 0.0 3.9e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 MCM P-loop domain AAA_16 PF13191.6 AIO02434.1 - 0.0031 17.9 0.2 0.021 15.2 0.2 2.4 1 1 0 1 1 1 1 AAA ATPase domain AAA PF00004.29 AIO02434.1 - 0.13 12.7 0.1 0.38 11.2 0.1 1.8 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) PHF5 PF03660.14 AIO02436.1 - 8.2e-34 115.9 9.8 9.3e-34 115.8 9.8 1.0 1 0 0 1 1 1 1 PHF5-like protein FYVE_2 PF02318.16 AIO02436.1 - 0.34 11.1 9.3 0.15 12.3 7.2 1.5 2 0 0 2 2 2 0 FYVE-type zinc finger zf-C3HC4_3 PF13920.6 AIO02436.1 - 1.3 8.9 14.0 0.043 13.7 4.3 2.6 2 1 1 3 3 3 0 Zinc finger, C3HC4 type (RING finger) DZR PF12773.7 AIO02436.1 - 2 8.5 11.7 12 6.0 10.7 2.5 1 1 1 2 2 2 0 Double zinc ribbon TF_Zn_Ribbon PF08271.12 AIO02436.1 - 5.3 6.6 9.2 0.87 9.1 0.8 2.4 2 1 0 2 2 2 0 TFIIB zinc-binding zf-RING_2 PF13639.6 AIO02437.1 - 1.8e-12 47.4 2.1 1.8e-12 47.4 2.1 2.2 2 0 0 2 2 2 1 Ring finger domain zf-RING_11 PF17123.5 AIO02437.1 - 6.5e-10 38.6 0.7 1.3e-09 37.6 0.7 1.6 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 AIO02437.1 - 1.7e-08 34.2 1.7 4e-08 33.0 1.7 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 AIO02437.1 - 2e-07 30.8 0.6 2e-07 30.8 0.6 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 AIO02437.1 - 5.4e-07 29.8 1.8 5.4e-07 29.8 1.8 2.0 1 1 1 2 2 2 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 AIO02437.1 - 2.7e-06 27.3 1.1 2.7e-06 27.3 1.1 1.9 2 0 0 2 2 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 AIO02437.1 - 4.5e-06 26.5 1.1 9.3e-06 25.5 1.1 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 AIO02437.1 - 1.1e-05 25.1 1.0 1.1e-05 25.1 1.0 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 AIO02437.1 - 0.0051 16.4 1.9 0.015 14.9 1.9 1.8 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-ANAPC11 PF12861.7 AIO02437.1 - 0.018 15.1 2.6 0.085 12.9 2.6 2.0 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Spt5_N PF11942.8 AIO02437.1 - 0.11 13.5 2.4 0.17 12.9 2.4 1.2 1 0 0 1 1 1 0 Spt5 transcription elongation factor, acidic N-terminal zf-C3HC4_4 PF15227.6 AIO02437.1 - 0.22 11.7 2.6 0.85 9.8 2.6 2.1 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.6 AIO02437.1 - 0.34 10.7 1.5 0.83 9.5 1.5 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-C3H2C3 PF17122.5 AIO02437.1 - 0.45 10.6 2.7 1.1 9.4 2.7 1.6 1 0 0 1 1 1 0 Zinc-finger FANCL_C PF11793.8 AIO02437.1 - 0.47 10.7 6.8 0.44 10.8 2.6 2.8 2 1 0 2 2 2 0 FANCL C-terminal domain Prok-RING_4 PF14447.6 AIO02437.1 - 0.83 9.6 7.4 0.077 12.9 2.2 1.9 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 PI3_PI4_kinase PF00454.27 AIO02438.1 - 5.2e-24 85.4 0.0 1e-23 84.5 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase NUC194 PF08163.12 AIO02438.1 - 5.2e-05 22.4 0.0 0.0016 17.4 0.0 2.6 3 0 0 3 3 3 1 NUC194 domain FATC PF02260.20 AIO02438.1 - 0.0026 17.6 0.0 0.0084 15.9 0.0 2.0 1 0 0 1 1 1 1 FATC domain ATP-grasp_2 PF08442.10 AIO02439.1 - 4.1e-64 215.9 4.0 6.5e-64 215.2 4.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain Ligase_CoA PF00549.19 AIO02439.1 - 1.2e-23 83.6 2.4 2.7e-23 82.5 0.9 2.3 2 0 0 2 2 2 1 CoA-ligase Succ_CoA_lig PF13607.6 AIO02439.1 - 0.03 14.1 0.5 0.071 12.9 0.5 1.6 1 0 0 1 1 1 0 Succinyl-CoA ligase like flavodoxin domain KleE PF17394.2 AIO02440.1 - 0.04 14.1 0.4 0.052 13.8 0.2 1.3 1 1 0 1 1 1 0 Uncharacterized KleE stable inheritance protein DUF1430 PF07242.11 AIO02441.1 - 0.04 14.2 0.4 0.088 13.1 0.2 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1430) DUF4499 PF14934.6 AIO02441.1 - 0.06 13.7 0.6 0.15 12.4 0.5 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4499) Bromodomain PF00439.25 AIO02442.1 - 2.9e-22 78.5 0.0 4.6e-22 77.9 0.0 1.3 1 0 0 1 1 1 1 Bromodomain DUF1635 PF07795.11 AIO02442.1 - 0.28 11.0 2.5 0.46 10.3 2.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1635) TFIIA PF03153.13 AIO02442.1 - 1.7 8.6 12.7 1.8 8.5 12.7 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit GTP1_OBG PF01018.22 AIO02443.1 - 1.2e-39 135.4 4.7 1.7e-39 134.9 4.7 1.2 1 0 0 1 1 1 1 GTP1/OBG MMR_HSR1 PF01926.23 AIO02443.1 - 4.4e-19 68.7 0.0 8.2e-19 67.8 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 AIO02443.1 - 3e-06 26.8 0.0 4.9e-05 22.9 0.0 2.2 2 0 0 2 2 2 1 Ferrous iron transport protein B rRNA_proc-arch PF13234.6 AIO02444.1 - 9e-46 157.0 2.0 1.6e-45 156.1 1.1 1.8 2 0 0 2 2 2 1 rRNA-processing arch domain DSHCT PF08148.12 AIO02444.1 - 4.3e-43 146.8 0.5 4.3e-43 146.8 0.5 2.2 2 0 0 2 2 2 1 DSHCT (NUC185) domain DEAD PF00270.29 AIO02444.1 - 1.1e-22 80.6 0.7 4.6e-21 75.4 0.0 2.8 3 0 0 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.31 AIO02444.1 - 6.9e-07 29.6 0.0 3.4e-06 27.4 0.0 2.3 2 1 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 AIO02444.1 - 1.1e-06 28.8 0.0 2.6e-06 27.5 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit FlxA PF14282.6 AIO02444.1 - 0.00078 19.4 1.9 0.0016 18.4 1.9 1.5 1 0 0 1 1 1 1 FlxA-like protein ATPase_2 PF01637.18 AIO02444.1 - 0.0021 18.0 0.8 0.028 14.3 0.0 2.5 3 0 0 3 3 3 1 ATPase domain predominantly from Archaea AAA_22 PF13401.6 AIO02444.1 - 0.016 15.5 0.0 0.08 13.2 0.0 2.2 2 0 0 2 2 2 0 AAA domain PhoH PF02562.16 AIO02444.1 - 0.022 14.2 0.0 0.052 13.0 0.0 1.6 1 0 0 1 1 1 0 PhoH-like protein T2SSE PF00437.20 AIO02444.1 - 0.042 12.9 0.0 0.12 11.5 0.0 1.7 1 0 0 1 1 1 0 Type II/IV secretion system protein DUF3856 PF12968.7 AIO02444.1 - 0.057 13.5 0.9 14 5.8 0.0 2.9 3 0 0 3 3 3 0 Domain of Unknown Function (DUF3856) Helicase_RecD PF05127.14 AIO02444.1 - 0.073 12.9 0.6 3.4 7.5 0.0 2.6 2 0 0 2 2 2 0 Helicase Syntaxin_2 PF14523.6 AIO02444.1 - 0.16 12.4 5.9 1.8 8.9 1.0 3.5 3 0 0 3 3 3 0 Syntaxin-like protein CobA_CobO_BtuR PF02572.15 AIO02444.1 - 0.17 12.2 0.6 1 9.6 0.0 2.6 4 0 0 4 4 4 0 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP Zot PF05707.12 AIO02444.1 - 0.17 11.5 0.0 0.49 10.0 0.0 1.7 1 1 0 1 1 1 0 Zonular occludens toxin (Zot) GSHPx PF00255.19 AIO02445.1 - 1.8e-26 91.8 0.0 2.2e-26 91.5 0.0 1.1 1 0 0 1 1 1 1 Glutathione peroxidase AhpC-TSA PF00578.21 AIO02445.1 - 0.0013 18.7 0.0 0.0018 18.2 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 AIO02445.1 - 0.19 11.5 0.0 0.24 11.1 0.0 1.1 1 0 0 1 1 1 0 Redoxin RNase_PH PF01138.21 AIO02446.1 - 3.8e-28 98.6 1.6 4.9e-28 98.3 0.6 1.7 2 0 0 2 2 2 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 AIO02446.1 - 1.1e-06 28.6 0.0 2.7e-06 27.3 0.0 1.7 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 DUF1623 PF07785.11 AIO02446.1 - 0.049 13.8 1.2 0.088 13.0 1.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1623) Adap_comp_sub PF00928.21 AIO02447.1 - 6.6e-54 183.0 0.0 8.2e-54 182.7 0.0 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 AIO02447.1 - 2.5e-08 34.0 1.7 4.7e-08 33.1 1.7 1.4 1 0 0 1 1 1 1 Clathrin adaptor complex small chain muHD PF10291.9 AIO02447.1 - 0.047 13.1 0.0 0.067 12.6 0.0 1.3 1 0 0 1 1 1 0 Muniscin C-terminal mu homology domain DUF5314 PF17241.2 AIO02447.1 - 0.093 12.4 0.1 0.18 11.5 0.1 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5314) RRM_1 PF00076.22 AIO02448.1 - 7.2e-08 32.1 0.0 1.2e-07 31.4 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 AIO02448.1 - 1e-07 31.6 0.0 1.2e-07 31.3 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Phage_Gp23 PF10669.9 AIO02448.1 - 0.03 14.6 3.2 0.044 14.1 3.2 1.2 1 0 0 1 1 1 0 Protein gp23 (Bacteriophage A118) Cullin PF00888.22 AIO02450.1 - 3.3e-64 217.6 0.1 4e-64 217.3 0.1 1.0 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 AIO02450.1 - 5.3e-09 36.0 0.0 4e-08 33.2 0.0 2.5 2 0 0 2 2 2 1 Cullin protein neddylation domain Fibrillarin PF01269.17 AIO02451.1 - 6.3e-101 336.2 0.0 7.1e-101 336.0 0.0 1.0 1 0 0 1 1 1 1 Fibrillarin GCD14 PF08704.10 AIO02451.1 - 0.00023 20.9 0.0 0.00031 20.5 0.0 1.2 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit PCMT PF01135.19 AIO02451.1 - 0.013 15.3 0.1 0.023 14.5 0.1 1.4 1 1 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) BPL_LplA_LipB PF03099.19 AIO02452.1 - 0.037 13.9 0.0 0.052 13.5 0.0 1.3 1 0 0 1 1 1 0 Biotin/lipoate A/B protein ligase family Thioredoxin PF00085.20 AIO02453.1 - 0.039 13.9 0.0 0.26 11.3 0.0 2.2 2 0 0 2 2 2 0 Thioredoxin T4_Gp59_N PF08993.10 AIO02453.1 - 0.12 12.8 0.0 0.25 11.8 0.0 1.5 1 0 0 1 1 1 0 T4 gene Gp59 loader of gp41 DNA helicase vATP-synt_E PF01991.18 AIO02454.1 - 9.7e-39 132.8 5.9 1.1e-38 132.7 5.9 1.0 1 0 0 1 1 1 1 ATP synthase (E/31 kDa) subunit Seipin PF06775.14 AIO02454.1 - 0.074 13.1 0.0 0.12 12.5 0.0 1.2 1 0 0 1 1 1 0 Putative adipose-regulatory protein (Seipin) Macscav_rec PF03523.13 AIO02455.1 - 0.12 12.3 0.2 0.27 11.1 0.2 1.6 1 0 0 1 1 1 0 Macrophage scavenger receptor BSD PF03909.17 AIO02455.1 - 0.15 12.1 0.1 0.4 10.7 0.1 1.7 1 0 0 1 1 1 0 BSD domain EF-hand_8 PF13833.6 AIO02456.1 - 0.00019 21.2 0.0 0.0055 16.5 0.0 2.5 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_7 PF13499.6 AIO02456.1 - 0.0049 17.3 0.0 0.37 11.3 0.0 2.9 2 1 1 3 3 3 2 EF-hand domain pair Hexapep PF00132.24 AIO02456.1 - 0.11 12.2 0.5 0.54 10.1 0.1 2.4 2 0 0 2 2 2 0 Bacterial transferase hexapeptide (six repeats) Pro_isomerase PF00160.21 AIO02457.1 - 4e-37 127.9 0.0 4.6e-37 127.7 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD ArfGap PF01412.18 AIO02459.1 - 2.9e-22 78.9 0.0 4.7e-22 78.3 0.0 1.3 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf IRF-2BP1_2 PF11261.8 AIO02459.1 - 0.13 11.9 0.3 0.25 10.9 0.3 1.3 1 0 0 1 1 1 0 Interferon regulatory factor 2-binding protein zinc finger REV1_C PF16727.5 AIO02459.1 - 0.22 11.9 0.1 0.39 11.1 0.1 1.3 1 0 0 1 1 1 0 DNA repair protein REV1 C-terminal domain TBCC PF07986.12 AIO02460.1 - 7.6e-25 87.0 0.8 1.5e-24 86.1 0.8 1.4 1 0 0 1 1 1 1 Tubulin binding cofactor C TBCC_N PF16752.5 AIO02460.1 - 0.0015 19.0 8.0 0.0024 18.3 8.0 1.3 1 0 0 1 1 1 1 Tubulin-specific chaperone C N-terminal domain TAN PF11640.8 AIO02460.1 - 0.006 16.7 0.2 0.01 16.0 0.2 1.3 1 0 0 1 1 1 1 Telomere-length maintenance and DNA damage repair DUF3395 PF11875.8 AIO02460.1 - 4 7.3 6.2 5.1 7.0 5.6 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF3395) cobW PF02492.19 AIO02461.1 - 7.8e-47 159.1 0.1 1e-46 158.8 0.1 1.1 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.14 AIO02461.1 - 0.0047 16.8 0.0 0.0085 16.0 0.0 1.4 1 0 0 1 1 1 1 Cobalamin synthesis protein cobW C-terminal domain RsgA_GTPase PF03193.16 AIO02461.1 - 0.014 15.3 0.1 3.7 7.4 0.0 2.4 2 0 0 2 2 2 0 RsgA GTPase AAA_33 PF13671.6 AIO02461.1 - 0.048 13.8 0.0 0.087 13.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 AIO02461.1 - 0.05 13.3 0.0 0.12 12.1 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain MobB PF03205.14 AIO02461.1 - 0.062 13.2 0.1 4.1 7.3 0.0 2.3 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_18 PF13238.6 AIO02461.1 - 0.072 13.6 0.0 0.83 10.2 0.0 2.2 2 0 0 2 2 2 0 AAA domain UPF0004 PF00919.20 AIO02461.1 - 0.079 13.0 1.5 0.18 11.9 0.4 2.0 2 0 0 2 2 2 0 Uncharacterized protein family UPF0004 AAA_22 PF13401.6 AIO02461.1 - 0.092 13.0 0.0 0.2 11.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain ATP_bind_1 PF03029.17 AIO02461.1 - 0.12 12.2 0.1 0.26 11.0 0.1 1.6 1 1 0 1 1 1 0 Conserved hypothetical ATP binding protein TsaE PF02367.17 AIO02461.1 - 0.13 12.3 0.0 0.25 11.3 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Guanylate_cyc PF00211.20 AIO02462.1 - 7.7e-38 130.0 0.0 1.5e-37 129.0 0.0 1.5 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain DUF1935 PF09149.10 AIO02462.1 - 1.6e-27 95.9 0.0 3.5e-27 94.8 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1935) PsbX PF06596.11 AIO02462.1 - 1.3 9.1 4.5 4.1 7.5 4.5 1.8 1 0 0 1 1 1 0 Photosystem II reaction centre X protein (PsbX) zf-CCHC PF00098.23 AIO02463.1 - 1.1e-18 66.4 78.4 0.00042 20.3 0.5 10.2 10 0 0 10 10 10 8 Zinc knuckle zf-CCHC_2 PF13696.6 AIO02463.1 - 6.4e-06 25.9 21.3 0.00078 19.2 2.0 9.6 8 1 1 9 9 9 4 Zinc knuckle zf-CCHC_4 PF14392.6 AIO02463.1 - 0.095 12.5 79.9 0.03 14.0 2.8 10.1 6 3 4 10 10 10 0 Zinc knuckle UPF0193 PF05250.11 AIO02463.1 - 0.16 11.8 0.1 0.42 10.4 0.0 1.7 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0193) NYN PF01936.18 AIO02463.1 - 0.2 12.1 0.0 0.46 11.0 0.0 1.7 1 1 0 1 1 1 0 NYN domain Topoisom_bac PF01131.20 AIO02464.1 - 5.2e-105 351.8 0.0 1.7e-104 350.1 0.0 1.7 2 0 0 2 2 2 1 DNA topoisomerase Toprim PF01751.22 AIO02464.1 - 1.7e-17 63.5 0.0 5.7e-17 61.8 0.0 1.9 2 0 0 2 2 2 1 Toprim domain zf-C4_Topoisom PF01396.19 AIO02464.1 - 1.9e-06 27.6 0.1 1.9e-06 27.6 0.1 5.0 5 0 0 5 5 5 1 Topoisomerase DNA binding C4 zinc finger zf-GRF PF06839.12 AIO02464.1 - 2.2e-06 27.6 1.2 2.2e-06 27.6 1.2 2.6 2 0 0 2 2 2 1 GRF zinc finger Cys_rich_CPCC PF14206.6 AIO02464.1 - 0.0058 16.4 1.4 0.095 12.5 0.9 2.8 2 0 0 2 2 2 1 Cysteine-rich CPCC HypA PF01155.19 AIO02464.1 - 0.61 10.1 13.1 0.46 10.5 0.6 4.1 2 1 1 3 3 3 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Terminase_GpA PF05876.12 AIO02464.1 - 2 6.9 3.5 3.3 6.2 3.5 1.2 1 0 0 1 1 1 0 Phage terminase large subunit (GpA) 14-3-3 PF00244.20 AIO02465.1 - 2.4e-84 282.3 0.2 2.8e-84 282.1 0.2 1.0 1 0 0 1 1 1 1 14-3-3 protein CdvA PF18822.1 AIO02466.1 - 0.0098 15.7 4.4 0.0098 15.7 4.4 7.4 5 2 0 6 6 6 3 CdvA-like coiled-coil domain GMC_oxred_N PF00732.19 AIO02467.1 - 1.5e-49 169.0 0.1 2.3e-49 168.3 0.1 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 AIO02467.1 - 1e-21 78.0 0.1 1.7e-21 77.3 0.1 1.4 1 0 0 1 1 1 1 GMC oxidoreductase Pyr_redox_2 PF07992.14 AIO02467.1 - 3.7e-07 29.7 0.4 0.00039 19.8 0.1 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 AIO02467.1 - 1.8e-05 24.0 8.0 0.0019 17.3 2.3 2.4 3 0 0 3 3 3 2 FAD binding domain DAO PF01266.24 AIO02467.1 - 0.00011 22.0 9.2 0.00013 21.7 0.9 3.3 3 2 0 3 3 3 1 FAD dependent oxidoreductase GIDA PF01134.22 AIO02467.1 - 0.00015 21.0 1.9 0.063 12.4 1.6 2.1 2 0 0 2 2 2 2 Glucose inhibited division protein A Lycopene_cycl PF05834.12 AIO02467.1 - 0.0018 17.4 1.3 0.0029 16.7 1.3 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_oxidored PF12831.7 AIO02467.1 - 0.0018 17.7 1.1 0.15 11.4 0.3 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 AIO02467.1 - 0.0018 18.4 1.4 0.034 14.4 1.0 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 AIO02467.1 - 0.0058 15.9 0.2 0.012 14.9 0.2 1.4 1 0 0 1 1 1 1 Thi4 family HI0933_like PF03486.14 AIO02467.1 - 0.0063 15.3 1.2 0.011 14.5 1.2 1.3 1 0 0 1 1 1 1 HI0933-like protein ComFB PF10719.9 AIO02468.1 - 0.047 13.8 0.1 0.09 12.9 0.1 1.4 1 0 0 1 1 1 0 Late competence development protein ComFB dCache_1 PF02743.18 AIO02469.1 - 0.00079 19.3 1.2 0.0033 17.2 0.1 2.1 2 0 0 2 2 2 1 Cache domain DUF1712 PF08217.11 AIO02470.1 - 6.9e-06 24.8 0.0 3e-05 22.7 0.0 1.9 2 0 0 2 2 2 1 Fungal domain of unknown function (DUF1712) Ribosomal_L20 PF00453.18 AIO02471.1 - 0.028 14.5 0.9 0.047 13.8 0.9 1.4 1 0 0 1 1 1 0 Ribosomal protein L20 Ubiquitin_4 PF18036.1 AIO02471.1 - 0.037 14.1 0.0 0.084 12.9 0.0 1.5 1 0 0 1 1 1 0 Ubiquitin-like domain UL42 PF17638.2 AIO02471.1 - 0.062 13.3 1.1 0.09 12.7 1.1 1.2 1 0 0 1 1 1 0 HCMV UL42 Ribosomal_L22e PF01776.17 AIO02472.1 - 1.2e-36 125.4 2.8 1.6e-36 125.0 2.8 1.1 1 0 0 1 1 1 1 Ribosomal L22e protein family ECH_2 PF16113.5 AIO02473.1 - 6.7e-24 85.0 0.0 3.9e-13 49.6 0.0 4.0 3 1 0 3 3 3 2 Enoyl-CoA hydratase/isomerase ECH_1 PF00378.20 AIO02473.1 - 2.7e-14 53.1 0.0 1.4e-09 37.7 0.0 2.3 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase EPO_TPO PF00758.18 AIO02473.1 - 0.018 15.1 0.0 0.055 13.5 0.0 1.8 1 1 1 2 2 2 0 Erythropoietin/thrombopoietin Macro PF01661.21 AIO02474.1 - 0.00013 22.0 0.0 0.00021 21.3 0.0 1.4 1 0 0 1 1 1 1 Macro domain Actin PF00022.19 AIO02476.1 - 1.4e-94 317.0 0.0 8.5e-94 314.5 0.0 1.8 1 1 0 1 1 1 1 Actin FtsA PF14450.6 AIO02476.1 - 0.044 14.2 0.1 0.32 11.4 0.0 2.2 2 1 0 2 2 2 0 Cell division protein FtsA Piezo_RRas_bdg PF12166.8 AIO02479.1 - 3e-87 293.7 0.0 4e-87 293.2 0.0 1.2 1 0 0 1 1 1 1 Piezo non-specific cation channel, R-Ras-binding domain DUF2644 PF10841.8 AIO02479.1 - 1.8 8.9 5.6 0.32 11.3 0.2 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF2644) Bromodomain PF00439.25 AIO02481.1 - 4.6e-13 49.0 0.0 1.1e-12 47.9 0.0 1.6 1 0 0 1 1 1 1 Bromodomain Ribosomal_L29e PF01779.17 AIO02484.1 - 7e-13 48.7 4.7 7e-13 48.7 4.7 1.9 2 0 0 2 2 2 1 Ribosomal L29e protein family Ribosomal_L29e PF01779.17 AIO02485.1 - 7e-13 48.7 4.7 7e-13 48.7 4.7 1.9 2 0 0 2 2 2 1 Ribosomal L29e protein family adh_short PF00106.25 AIO02486.1 - 1.9e-36 125.4 0.0 2.4e-36 125.0 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 AIO02486.1 - 5e-14 52.4 0.0 7.9e-14 51.8 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 AIO02486.1 - 1.2e-10 41.6 1.5 2.8e-07 30.6 0.2 2.4 2 0 0 2 2 2 2 KR domain Methyltransf_31 PF13847.6 AIO02486.1 - 0.0044 16.8 0.0 0.0094 15.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 AIO02486.1 - 0.059 12.7 0.0 0.093 12.1 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Pyr_redox PF00070.27 AIO02486.1 - 0.073 13.6 0.3 0.14 12.7 0.3 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase DUF1776 PF08643.10 AIO02486.1 - 0.083 12.3 0.0 0.13 11.7 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) Vps26 PF03643.15 AIO02487.1 - 3.8e-54 183.5 0.6 4.8e-54 183.2 0.6 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 Arrestin_N PF00339.29 AIO02487.1 - 0.00027 21.0 1.1 1.4 9.0 0.0 3.1 3 0 0 3 3 3 2 Arrestin (or S-antigen), N-terminal domain CRAL_TRIO PF00650.20 AIO02488.1 - 4.1e-28 98.1 0.0 6e-28 97.6 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.6 AIO02488.1 - 0.12 12.6 0.0 0.23 11.6 0.0 1.4 1 0 0 1 1 1 0 Divergent CRAL/TRIO domain Snf7 PF03357.21 AIO02489.1 - 2.4e-28 98.9 27.8 2.4e-28 98.9 27.8 1.9 1 1 1 2 2 2 1 Snf7 MalF_P2 PF14785.6 AIO02489.1 - 0.08 13.0 3.9 0.13 12.2 3.9 1.4 1 0 0 1 1 1 0 Maltose transport system permease protein MalF P2 domain Glyco_transf_25 PF01755.17 AIO02490.1 - 1.3e-11 44.7 0.0 1.2e-10 41.6 0.0 2.3 1 1 0 1 1 1 1 Glycosyltransferase family 25 (LPS biosynthesis protein) NIPSNAP PF07978.13 AIO02491.1 - 3.1e-15 56.2 0.1 8.7e-15 54.8 0.0 1.7 2 0 0 2 2 2 1 NIPSNAP Transket_pyr PF02779.24 AIO02492.1 - 3.6e-56 189.6 0.1 1e-55 188.2 0.0 1.8 2 0 0 2 2 2 1 Transketolase, pyrimidine binding domain E1_dh PF00676.20 AIO02492.1 - 1.7e-52 178.2 0.0 2.9e-52 177.5 0.0 1.2 1 0 0 1 1 1 1 Dehydrogenase E1 component OxoGdeHyase_C PF16870.5 AIO02492.1 - 3.4e-43 147.0 0.0 5.9e-43 146.2 0.0 1.4 1 0 0 1 1 1 1 2-oxoglutarate dehydrogenase C-terminal 2-oxogl_dehyd_N PF16078.5 AIO02492.1 - 5.9e-16 57.8 1.4 1.3e-15 56.7 0.7 1.9 2 0 0 2 2 2 1 2-oxoglutarate dehydrogenase N-terminus SMAP PF15477.6 AIO02493.1 - 5.2e-09 36.9 6.9 5.2e-09 36.9 6.9 1.8 2 1 0 2 2 2 1 Small acidic protein family zf-U11-48K PF05253.12 AIO02493.1 - 7.5 6.6 6.0 1.7 8.7 2.1 2.0 2 0 0 2 2 2 0 U11-48K-like CHHC zinc finger DUF2870 PF11069.8 AIO02494.1 - 1.1e-25 89.9 0.0 3.1e-25 88.4 0.0 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF2870) EP400_N PF15790.5 AIO02494.1 - 0.11 11.3 0.0 0.16 10.8 0.0 1.1 1 0 0 1 1 1 0 E1A-binding protein p400, N-terminal DUF1127 PF06568.11 AIO02494.1 - 0.26 11.1 2.4 0.71 9.6 2.4 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1127) DUF3658 PF12395.8 AIO02495.1 - 0.02 14.8 0.7 0.72 9.8 0.0 2.8 2 0 0 2 2 2 0 Protein of unknown function DivIC PF04977.15 AIO02495.1 - 0.036 13.8 0.0 0.036 13.8 0.0 2.9 2 0 0 2 2 2 0 Septum formation initiator Rota_NSP4 PF01452.16 AIO02495.1 - 0.26 11.0 2.6 0.51 10.0 2.6 1.4 1 0 0 1 1 1 0 Rotavirus non structural protein YabA PF06156.13 AIO02495.1 - 0.67 10.6 6.0 0.44 11.2 0.2 2.8 1 1 1 2 2 2 0 Initiation control protein YabA PTPlike_phytase PF14566.6 AIO02495.1 - 0.77 9.9 4.8 2.6 8.1 4.8 1.9 1 0 0 1 1 1 0 Inositol hexakisphosphate SidE PF12252.8 AIO02495.1 - 0.89 7.0 6.8 1.3 6.5 6.8 1.1 1 0 0 1 1 1 0 Dot/Icm substrate protein TMCO5 PF14992.6 AIO02495.1 - 7.2 6.1 14.2 2.6 7.6 7.4 2.5 3 0 0 3 3 3 0 TMCO5 family Prefoldin_2 PF01920.20 AIO02496.1 - 0.021 14.8 1.0 0.073 13.0 0.3 2.0 2 0 0 2 2 2 0 Prefoldin subunit Erythro-docking PF09277.11 AIO02496.1 - 0.52 10.3 4.7 2.7 7.9 0.1 3.0 3 1 0 3 3 3 0 Erythronolide synthase, docking COE1_DBD PF16422.5 AIO02497.1 - 0.02 14.3 0.1 0.029 13.8 0.1 1.1 1 0 0 1 1 1 0 Transcription factor COE1 DNA-binding domain DUF2150 PF09920.9 AIO02497.1 - 0.2 11.6 0.3 0.83 9.6 0.0 1.9 1 1 1 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2150) TPR_1 PF00515.28 AIO02498.1 - 0.00066 19.4 0.2 0.00066 19.4 0.2 3.6 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_11 PF13414.6 AIO02498.1 - 0.0064 16.2 1.4 1.6 8.5 0.9 3.1 3 0 0 3 3 3 2 TPR repeat DUF3846 PF12957.7 AIO02498.1 - 0.013 15.8 0.0 0.053 13.8 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3846) TPR_2 PF07719.17 AIO02498.1 - 0.042 14.0 0.1 0.042 14.0 0.1 3.5 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_9 PF13371.6 AIO02498.1 - 0.25 11.5 2.4 0.23 11.6 0.7 1.9 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_16 PF13432.6 AIO02498.1 - 0.75 10.5 7.8 1.8 9.3 4.3 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat SQS_PSY PF00494.19 AIO02500.1 - 8.8e-13 48.4 0.1 1.3e-12 47.8 0.1 1.2 1 0 0 1 1 1 1 Squalene/phytoene synthase TetR_C_20 PF17925.1 AIO02500.1 - 0.097 13.0 0.0 0.25 11.7 0.0 1.6 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain SRP54 PF00448.22 AIO02501.1 - 7.6e-55 185.6 0.1 1.7e-54 184.4 0.1 1.6 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain SRP-alpha_N PF04086.13 AIO02501.1 - 8.3e-20 71.9 0.3 1.4e-19 71.1 0.3 1.4 1 0 0 1 1 1 1 Signal recognition particle, alpha subunit, N-terminal SRP54_N PF02881.19 AIO02501.1 - 3.8e-09 36.6 0.0 8.2e-09 35.6 0.0 1.6 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain AAA_22 PF13401.6 AIO02501.1 - 2e-06 28.1 0.0 1.2e-05 25.6 0.0 2.3 1 1 1 2 2 2 1 AAA domain AAA_30 PF13604.6 AIO02501.1 - 1.4e-05 24.9 0.1 2.7e-05 24.0 0.1 1.4 1 0 0 1 1 1 1 AAA domain NTPase_1 PF03266.15 AIO02501.1 - 0.00017 21.6 0.0 0.65 9.9 0.0 2.4 2 0 0 2 2 2 2 NTPase Zeta_toxin PF06414.12 AIO02501.1 - 0.00031 20.1 0.3 0.0063 15.8 0.0 2.7 2 2 1 3 3 3 1 Zeta toxin AAA_17 PF13207.6 AIO02501.1 - 0.0029 18.1 0.0 0.011 16.2 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 AIO02501.1 - 0.0074 16.7 0.1 0.034 14.5 0.1 2.0 1 1 0 1 1 1 1 AAA ATPase domain ArsA_ATPase PF02374.15 AIO02501.1 - 0.0074 15.5 0.1 0.039 13.1 0.0 2.0 2 0 0 2 2 2 1 Anion-transporting ATPase ETF PF01012.21 AIO02501.1 - 0.013 15.4 0.1 0.32 10.9 0.0 2.4 2 0 0 2 2 2 0 Electron transfer flavoprotein domain NACHT PF05729.12 AIO02501.1 - 0.016 15.1 0.0 0.48 10.3 0.0 2.6 3 0 0 3 3 3 0 NACHT domain AAA_24 PF13479.6 AIO02501.1 - 0.017 14.8 0.1 0.23 11.1 0.0 2.7 3 1 0 3 3 3 0 AAA domain CbiA PF01656.23 AIO02501.1 - 0.021 14.9 0.0 0.099 12.7 0.0 2.2 2 1 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain APS_kinase PF01583.20 AIO02501.1 - 0.024 14.5 0.0 0.073 13.0 0.0 1.8 2 0 0 2 2 2 0 Adenylylsulphate kinase MMR_HSR1 PF01926.23 AIO02501.1 - 0.028 14.5 1.0 0.56 10.3 0.6 3.0 3 1 0 3 3 3 0 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 AIO02501.1 - 0.081 12.8 0.0 1.7 8.6 0.0 2.5 2 0 0 2 2 2 0 RsgA GTPase DAP3 PF10236.9 AIO02501.1 - 0.092 11.9 0.0 0.17 11.0 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 SCAB-PH PF17684.1 AIO02501.1 - 0.092 13.0 0.0 0.25 11.6 0.0 1.7 1 0 0 1 1 1 0 PH domain of plant-specific actin-binding protein ABC_tran PF00005.27 AIO02501.1 - 0.12 12.9 0.0 0.29 11.7 0.0 1.6 1 0 0 1 1 1 0 ABC transporter AAA_33 PF13671.6 AIO02501.1 - 0.13 12.5 0.1 0.38 10.9 0.1 1.8 1 1 0 1 1 1 0 AAA domain Longin PF13774.6 AIO02501.1 - 0.15 12.1 0.1 0.33 11.0 0.1 1.5 1 0 0 1 1 1 0 Regulated-SNARE-like domain DUF2009 PF09418.10 AIO02502.1 - 7.8e-157 523.0 0.0 9.2e-157 522.7 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2009) PALP PF00291.25 AIO02503.1 - 9.5e-59 199.2 1.3 1.1e-58 199.0 1.3 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme PG_isomerase_N PF18353.1 AIO02503.1 - 0.063 13.7 0.0 0.19 12.2 0.0 1.9 1 1 0 1 1 1 0 Phosphoglucose isomerase N-terminal domain EF-hand_7 PF13499.6 AIO02506.1 - 2.7e-09 37.3 0.2 4.6e-09 36.6 0.1 1.4 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_8 PF13833.6 AIO02506.1 - 3.6e-05 23.5 0.0 0.046 13.6 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 AIO02506.1 - 0.00032 20.4 0.0 0.16 12.0 0.0 2.4 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.32 AIO02506.1 - 0.0055 16.2 0.0 1.2 8.8 0.0 2.5 2 0 0 2 2 2 2 EF hand Shisa PF13908.6 AIO02507.1 - 0.0022 18.3 1.4 0.0045 17.3 1.4 1.6 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator MLANA PF14991.6 AIO02507.1 - 0.029 14.6 0.0 0.052 13.8 0.0 1.5 1 0 0 1 1 1 0 Protein melan-A DAG1 PF05454.11 AIO02507.1 - 0.032 13.6 0.1 0.056 12.8 0.1 1.3 1 0 0 1 1 1 0 Dystroglycan (Dystrophin-associated glycoprotein 1) Nitroreductase PF00881.24 AIO02507.1 - 0.038 14.0 0.1 0.058 13.4 0.1 1.4 1 0 0 1 1 1 0 Nitroreductase family Mem_trans PF03547.18 AIO02507.1 - 0.14 10.5 0.5 0.18 10.2 0.5 1.1 1 0 0 1 1 1 0 Membrane transport protein WD40 PF00400.32 AIO02509.1 - 9e-12 45.3 11.3 0.0085 16.9 0.2 5.7 5 0 0 5 5 5 5 WD domain, G-beta repeat NUDIX PF00293.28 AIO02511.1 - 4.2e-12 46.3 0.0 7e-12 45.5 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain EF-hand_7 PF13499.6 AIO02513.1 - 4.6e-27 94.3 4.2 8.4e-14 51.8 0.3 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 AIO02513.1 - 3e-25 85.9 9.9 4.3e-06 25.9 1.2 4.1 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.6 AIO02513.1 - 3.5e-20 70.1 8.6 1.6e-05 24.4 0.2 4.6 4 2 1 5 5 5 4 EF-hand domain EF-hand_8 PF13833.6 AIO02513.1 - 3.7e-20 71.5 7.8 3.2e-09 36.5 0.7 3.1 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_5 PF13202.6 AIO02513.1 - 1.4e-12 46.5 10.2 0.00091 18.6 0.8 4.3 4 1 0 4 4 4 3 EF hand EF-hand_9 PF14658.6 AIO02513.1 - 6.3e-08 32.8 0.3 0.016 15.5 0.1 2.8 2 1 1 3 3 3 2 EF-hand domain EF-hand_4 PF12763.7 AIO02513.1 - 5.1e-05 23.2 4.6 0.011 15.7 0.7 3.0 1 1 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand Caleosin PF05042.13 AIO02513.1 - 0.043 13.7 0.3 0.19 11.6 0.1 2.2 2 2 1 3 3 3 0 Caleosin related protein IFR3_antag PF14754.6 AIO02513.1 - 0.087 12.0 0.0 0.11 11.6 0.0 1.1 1 0 0 1 1 1 0 Papain-like auto-proteinase Pkinase PF00069.25 AIO02514.1 - 4.3e-58 196.8 0.0 6.8e-57 192.8 0.0 2.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 AIO02514.1 - 1.7e-31 109.5 0.0 8.5e-31 107.2 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase PAS PF00989.25 AIO02514.1 - 5.2e-05 23.2 0.0 0.00019 21.4 0.0 1.9 1 0 0 1 1 1 1 PAS fold RIO1 PF01163.22 AIO02514.1 - 0.0013 18.3 0.0 0.011 15.3 0.0 2.2 2 0 0 2 2 2 1 RIO1 family Pkinase_fungal PF17667.1 AIO02514.1 - 0.0014 17.5 0.0 0.0028 16.5 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase PAS_9 PF13426.7 AIO02514.1 - 0.0023 18.1 0.0 0.0061 16.8 0.0 1.7 1 0 0 1 1 1 1 PAS domain APH PF01636.23 AIO02514.1 - 0.0032 17.4 0.0 0.0066 16.4 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.6 AIO02514.1 - 0.0094 15.3 0.0 0.086 12.1 0.0 2.2 2 0 0 2 2 2 1 Kinase-like DUF2721 PF11026.8 AIO02514.1 - 0.0098 15.8 2.0 0.025 14.5 2.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2721) FTA2 PF13095.6 AIO02514.1 - 0.01 15.5 0.0 0.02 14.5 0.0 1.4 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 Amastin PF07344.11 AIO02514.1 - 0.013 15.4 2.8 0.035 14.0 2.8 1.7 1 0 0 1 1 1 0 Amastin surface glycoprotein PAS_4 PF08448.10 AIO02514.1 - 0.04 14.2 0.0 2.1 8.6 0.0 2.5 2 0 0 2 2 2 0 PAS fold OKR_DC_1_N PF03709.15 AIO02514.1 - 0.064 13.5 0.1 0.25 11.6 0.1 2.0 1 0 0 1 1 1 0 Orn/Lys/Arg decarboxylase, N-terminal domain Kdo PF06293.14 AIO02514.1 - 0.15 11.4 0.1 0.3 10.4 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family CLP1_P PF16575.5 AIO02517.1 - 6.1e-10 39.2 0.0 1e-08 35.2 0.0 2.2 1 1 0 1 1 1 1 mRNA cleavage and polyadenylation factor CLP1 P-loop Clp1 PF06807.14 AIO02517.1 - 0.0013 19.1 0.1 0.0037 17.7 0.0 1.8 2 0 0 2 2 2 1 Pre-mRNA cleavage complex II protein Clp1 FtsK_SpoIIIE PF01580.18 AIO02517.1 - 0.013 14.8 0.0 0.022 14.1 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family CLP1_N PF16573.5 AIO02517.1 - 0.056 13.7 0.0 0.11 12.7 0.0 1.5 1 0 0 1 1 1 0 N-terminal beta-sandwich domain of polyadenylation factor DUF498 PF04430.14 AIO02518.1 - 3.8e-19 68.7 0.0 7.1e-19 67.9 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF498/DUF598) tRNA_int_endo PF01974.17 AIO02519.1 - 4.2e-15 55.6 0.0 6.6e-15 55.0 0.0 1.3 1 0 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain Ribosomal_L34e PF01199.18 AIO02520.1 - 3e-27 94.7 2.5 3e-27 94.7 2.5 2.2 2 1 0 2 2 2 1 Ribosomal protein L34e NACHT_N PF17100.5 AIO02520.1 - 1.1 9.1 7.2 1.7 8.5 7.2 1.2 1 0 0 1 1 1 0 N-terminal domain of NWD NACHT-NTPase AAA_assoc_C PF09821.9 AIO02520.1 - 3.9 8.0 6.4 4.4 7.9 5.5 1.5 1 1 1 2 2 2 0 C-terminal AAA-associated domain MscS_TM PF12794.7 AIO02520.1 - 6.7 5.5 4.9 8.8 5.1 4.9 1.3 1 0 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 Ribosomal_S27e PF01667.17 AIO02521.1 - 4.1e-22 77.7 3.0 5e-22 77.4 3.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S27 FYVE_2 PF02318.16 AIO02521.1 - 0.019 15.2 0.7 0.022 15.0 0.7 1.1 1 0 0 1 1 1 0 FYVE-type zinc finger Zn_Tnp_IS1595 PF12760.7 AIO02521.1 - 0.023 14.7 1.8 0.037 14.0 1.8 1.5 1 0 0 1 1 1 0 Transposase zinc-ribbon domain HypA PF01155.19 AIO02521.1 - 0.12 12.4 1.8 0.14 12.2 1.8 1.2 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zinc_ribbon_4 PF13717.6 AIO02521.1 - 0.17 11.8 4.7 4.1 7.4 4.7 2.4 1 1 0 1 1 1 0 zinc-ribbon domain Ribosomal_L1 PF00687.21 AIO02522.1 - 4.2e-41 140.9 2.3 5.2e-41 140.6 2.3 1.0 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family NAC PF01849.18 AIO02523.1 - 3.3e-17 62.2 0.0 4.7e-17 61.7 0.0 1.3 1 0 0 1 1 1 1 NAC domain Carbam_trans_N PF02543.15 AIO02523.1 - 0.061 13.0 0.0 0.075 12.7 0.0 1.2 1 0 0 1 1 1 0 Carbamoyltransferase N-terminus MORN PF02493.20 AIO02524.1 - 1e-14 53.5 59.7 6.3e-05 22.6 1.2 9.5 10 0 0 10 10 10 7 MORN repeat DUF448 PF04296.13 AIO02524.1 - 0.03 14.2 5.1 11 6.0 0.0 4.9 5 3 2 7 7 7 0 Protein of unknown function (DUF448) DUF2766 PF10964.8 AIO02524.1 - 0.13 12.3 0.0 0.2 11.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2766) PPV_E2_N PF00508.17 AIO02524.1 - 1.3 8.3 9.5 0.47 9.8 2.3 2.3 2 0 0 2 2 2 0 E2 (early) protein, N terminal CH PF00307.31 AIO02525.1 - 7.6e-05 22.9 0.0 0.00016 21.8 0.0 1.5 1 0 0 1 1 1 1 Calponin homology (CH) domain Sipho_Gp157 PF05565.11 AIO02525.1 - 0.003 17.6 0.4 0.003 17.6 0.4 1.9 2 0 0 2 2 2 1 Siphovirus Gp157 GCV_T PF01571.21 AIO02526.1 - 4.4e-78 262.2 0.3 5.3e-78 261.9 0.3 1.1 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.11 AIO02526.1 - 1.1e-20 73.3 0.3 2.8e-20 72.0 0.3 1.6 1 0 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain TolA_bind_tri PF16331.5 AIO02527.1 - 0.011 15.7 3.0 0.02 15.0 3.0 1.4 1 0 0 1 1 1 0 TolA binding protein trimerisation Gon7 PF08738.10 AIO02527.1 - 0.041 14.0 0.1 1.8 8.7 0.1 2.1 2 0 0 2 2 2 0 Gon7 family bZIP_2 PF07716.15 AIO02527.1 - 1.5 9.0 8.2 0.77 9.9 3.0 2.2 2 0 0 2 2 2 0 Basic region leucine zipper zf-C3HC4_3 PF13920.6 AIO02528.1 - 2.7e-17 62.4 36.7 7.3e-12 45.0 16.2 4.5 4 1 1 5 5 5 2 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 AIO02528.1 - 7.5e-05 22.5 41.2 0.00023 20.9 15.2 3.6 3 1 1 4 4 4 2 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 AIO02528.1 - 0.004 17.1 16.6 0.004 17.1 16.6 4.1 4 0 0 4 4 4 2 zinc-RING finger domain zf-RING_2 PF13639.6 AIO02528.1 - 0.049 14.0 17.1 0.049 14.0 17.1 4.9 4 2 0 4 4 4 0 Ring finger domain HGTP_anticodon PF03129.20 AIO02529.1 - 1.2e-17 63.8 0.0 2.4e-17 62.9 0.0 1.5 1 0 0 1 1 1 1 Anticodon binding domain tRNA-synt_2b PF00587.25 AIO02529.1 - 3.5e-07 30.4 0.0 2.7e-06 27.5 0.0 2.1 2 1 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) Snf7 PF03357.21 AIO02530.1 - 1.2e-31 109.6 27.1 1.2e-31 109.6 27.1 1.5 2 0 0 2 2 2 1 Snf7 Fic_N PF13784.6 AIO02530.1 - 0.027 14.5 0.7 0.062 13.3 0.2 1.9 1 1 1 2 2 2 0 Fic/DOC family N-terminal DUF4407 PF14362.6 AIO02530.1 - 3.3 7.0 16.3 4.3 6.6 1.7 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) HAP2-GCS1 PF10699.9 AIO02531.1 - 8e-16 57.8 0.1 1.9e-15 56.6 0.1 1.7 1 0 0 1 1 1 1 Male gamete fusion factor Big_1 PF02369.16 AIO02531.1 - 0.059 13.4 1.5 1.2 9.2 0.1 3.1 2 0 0 2 2 2 0 Bacterial Ig-like domain (group 1) Dicty_CTDC PF00526.18 AIO02531.1 - 0.4 10.6 6.1 1.4 8.9 0.0 3.3 4 0 0 4 4 4 0 Dictyostelium (slime mold) repeat LRR_6 PF13516.6 AIO02532.1 - 0.00073 19.4 0.1 0.48 10.6 0.0 3.1 3 0 0 3 3 3 2 Leucine Rich repeat Flot PF15975.5 AIO02532.1 - 0.055 13.7 2.8 0.27 11.4 2.0 2.2 2 0 0 2 2 2 0 Flotillin Gasdermin_C PF17708.1 AIO02532.1 - 0.088 12.9 0.7 0.16 12.1 0.7 1.3 1 0 0 1 1 1 0 Gasdermin PUB domain WD40 PF00400.32 AIO02533.1 - 3.9e-14 52.8 3.1 0.00034 21.4 0.0 5.7 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 AIO02533.1 - 9.9e-09 35.4 0.0 1.5 9.2 0.0 5.1 2 2 4 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 AIO02533.1 - 0.032 13.2 0.0 0.16 10.9 0.0 2.2 2 1 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein MAM33 PF02330.16 AIO02534.1 - 1.4e-05 25.2 0.0 6.5e-05 23.0 0.0 1.8 2 0 0 2 2 2 1 Mitochondrial glycoprotein DUF982 PF06169.12 AIO02535.1 - 0.015 15.4 1.2 0.053 13.6 0.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF982) AdoHcyase PF05221.17 AIO02536.1 - 5.2e-131 436.2 0.0 1.4e-73 247.6 0.0 2.0 1 1 1 2 2 2 2 S-adenosyl-L-homocysteine hydrolase AdoHcyase_NAD PF00670.21 AIO02536.1 - 2.8e-85 284.3 2.4 4e-85 283.8 2.4 1.2 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 2-Hacid_dh_C PF02826.19 AIO02536.1 - 9.8e-10 38.1 0.0 1.9e-09 37.1 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IlvN PF07991.12 AIO02536.1 - 5.3e-05 22.8 0.1 9.5e-05 22.0 0.1 1.5 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain TrkA_N PF02254.18 AIO02536.1 - 0.00015 22.0 0.2 0.00065 20.0 0.2 2.2 1 1 0 1 1 1 1 TrkA-N domain NAD_binding_7 PF13241.6 AIO02536.1 - 0.00036 20.9 0.2 0.0009 19.7 0.2 1.7 1 0 0 1 1 1 1 Putative NAD(P)-binding PALP PF00291.25 AIO02536.1 - 0.019 14.4 0.6 0.054 12.9 0.2 1.8 2 0 0 2 2 2 0 Pyridoxal-phosphate dependent enzyme Oxidored_nitro PF00148.19 AIO02536.1 - 0.024 13.4 0.0 0.043 12.5 0.0 1.5 2 0 0 2 2 2 0 Nitrogenase component 1 type Oxidoreductase ELFV_dehydrog PF00208.21 AIO02536.1 - 0.038 13.7 0.0 0.075 12.7 0.0 1.5 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Telomerase_RBD PF12009.8 AIO02538.1 - 4.4e-23 81.9 0.1 8.4e-23 80.9 0.1 1.5 1 0 0 1 1 1 1 Telomerase ribonucleoprotein complex - RNA binding domain RVT_1 PF00078.27 AIO02538.1 - 0.00066 19.3 0.0 0.0018 17.8 0.0 1.7 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RecC_C PF17946.1 AIO02540.1 - 0.0048 16.7 3.8 0.2 11.4 0.2 2.1 1 1 1 2 2 2 2 RecC C-terminal domain Focal_AT PF03623.13 AIO02540.1 - 0.013 15.5 0.2 0.013 15.5 0.2 2.3 2 0 0 2 2 2 0 Focal adhesion targeting region DUF1729 PF08354.10 AIO02540.1 - 0.04 12.8 4.9 0.054 12.4 4.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1729) Bacillus_HBL PF05791.11 AIO02540.1 - 0.052 13.4 0.4 0.052 13.4 0.4 2.5 2 2 0 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) Prefoldin PF02996.17 AIO02540.1 - 0.056 13.4 6.4 2.9 7.8 0.1 3.2 3 0 0 3 3 3 0 Prefoldin subunit RACo_linker PF17650.1 AIO02540.1 - 0.056 13.3 0.7 3.8 7.4 0.0 2.4 2 0 0 2 2 2 0 RACo linker region Glyco_hydro_3_C PF01915.22 AIO02540.1 - 0.074 13.0 1.4 0.83 9.6 1.4 2.0 1 1 0 1 1 1 0 Glycosyl hydrolase family 3 C-terminal domain GSCFA PF08885.11 AIO02540.1 - 0.13 11.8 0.9 0.19 11.4 0.9 1.4 1 1 0 1 1 1 0 GSCFA family DUF4474 PF14751.6 AIO02540.1 - 0.16 11.4 0.5 1.1 8.6 0.1 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4474) Fez1 PF06818.15 AIO02540.1 - 0.74 10.2 13.5 0.22 12.0 8.3 2.2 1 1 2 3 3 3 0 Fez1 Sulfatase_C PF14707.6 AIO02540.1 - 0.8 10.5 3.0 21 5.9 0.2 2.4 1 1 0 2 2 2 0 C-terminal region of aryl-sulfatase CDC73_C PF05179.14 AIO02543.1 - 6.7e-32 110.3 0.0 9.8e-32 109.8 0.0 1.2 1 0 0 1 1 1 1 RNA pol II accessory factor, Cdc73 family, C-terminal Proteasome PF00227.26 AIO02544.1 - 7e-25 87.6 0.3 1.8e-24 86.3 0.3 1.6 1 1 0 1 1 1 1 Proteasome subunit Rieske PF00355.26 AIO02545.1 - 0.017 15.1 0.0 0.028 14.4 0.0 1.4 1 0 0 1 1 1 0 Rieske [2Fe-2S] domain V-SNARE_C PF12352.8 AIO02547.1 - 4.6e-07 30.0 1.3 4.6e-07 30.0 1.3 1.9 2 0 0 2 2 2 1 Snare region anchored in the vesicle membrane C-terminus SSFA2_C PF14723.6 AIO02547.1 - 0.0017 18.3 2.7 0.0028 17.6 0.1 2.1 2 0 0 2 2 2 1 Sperm-specific antigen 2 C-terminus SesA PF17107.5 AIO02547.1 - 0.026 14.7 0.8 5.7 7.2 0.1 2.9 2 1 1 3 3 3 0 N-terminal domain on NACHT_NTPase and P-loop NTPases RD3 PF14473.6 AIO02547.1 - 0.049 13.5 1.1 0.29 11.0 0.1 2.4 2 0 0 2 2 2 0 RD3 protein Sec20 PF03908.13 AIO02547.1 - 0.11 12.4 0.3 0.53 10.2 0.1 2.1 2 0 0 2 2 2 0 Sec20 Peptidase_M14 PF00246.24 AIO02548.1 - 5.1e-16 59.3 0.0 2.7e-15 56.9 0.0 2.1 1 1 0 1 1 1 1 Zinc carboxypeptidase AstE_AspA PF04952.14 AIO02548.1 - 6.6e-08 32.0 0.1 1.1e-07 31.3 0.1 1.3 1 0 0 1 1 1 1 Succinylglutamate desuccinylase / Aspartoacylase family Pepdidase_M14_N PF18027.1 AIO02548.1 - 4.7e-07 30.1 0.0 9e-07 29.2 0.0 1.5 1 0 0 1 1 1 1 Cytosolic carboxypeptidase N-terminal domain Gp_dh_C PF02800.20 AIO02548.1 - 0.078 12.6 0.3 0.34 10.5 0.1 2.0 2 0 0 2 2 2 0 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain TPR_2 PF07719.17 AIO02549.1 - 1.8e-05 24.5 4.1 1.6 9.0 0.0 3.7 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_12 PF13424.6 AIO02549.1 - 0.00021 21.5 6.8 0.23 11.8 0.3 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 AIO02549.1 - 0.0023 18.6 6.6 4.2 8.1 0.0 3.8 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.28 AIO02549.1 - 0.0025 17.6 1.4 1.7 8.6 0.0 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.6 AIO02549.1 - 0.0063 16.5 4.7 1.2 9.4 0.0 3.6 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.6 AIO02549.1 - 0.029 14.9 4.0 0.46 11.0 0.0 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.6 AIO02549.1 - 0.043 14.0 0.3 16 6.0 0.1 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.6 AIO02549.1 - 0.36 11.5 2.2 4.9 8.0 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF913 PF06025.12 AIO02549.1 - 0.64 8.9 2.3 1 8.3 2.3 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) SKA1 PF07160.12 AIO02549.1 - 7 6.4 6.5 6.4 6.6 4.4 1.9 2 0 0 2 2 2 0 Spindle and kinetochore-associated protein 1 RCC1 PF00415.18 AIO02550.1 - 4.8e-38 129.5 11.9 7.3e-10 39.3 0.1 7.3 7 1 0 7 7 7 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 AIO02550.1 - 1.1e-17 63.3 28.0 1.1e-06 28.2 3.2 7.2 7 1 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat His_Phos_1 PF00300.22 AIO02551.1 - 1.3e-13 51.0 7.6 2.1e-06 27.5 0.1 3.7 1 1 3 4 4 4 3 Histidine phosphatase superfamily (branch 1) FIVAR PF07554.13 AIO02551.1 - 0.057 14.2 0.6 0.099 13.4 0.6 1.3 1 0 0 1 1 1 0 FIVAR domain CREPT PF16566.5 AIO02551.1 - 0.097 12.8 0.3 0.17 12.1 0.3 1.4 1 0 0 1 1 1 0 Cell-cycle alteration and expression-elevated protein in tumour Smr PF01713.21 AIO02551.1 - 0.12 12.8 0.0 0.45 10.9 0.0 2.0 1 0 0 1 1 1 0 Smr domain DUF3813 PF12758.7 AIO02551.1 - 2.3 8.6 7.7 0.83 10.0 3.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3813) IQ PF00612.27 AIO02552.1 - 1.5e-13 49.2 6.9 0.0013 18.3 0.1 3.8 3 0 0 3 3 3 3 IQ calmodulin-binding motif Glyco_hydro_31 PF01055.26 AIO02554.1 - 1.4e-50 172.8 0.0 2e-50 172.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Amastin PF07344.11 AIO02557.1 - 1e-06 28.7 5.4 1.3e-06 28.4 5.4 1.1 1 0 0 1 1 1 1 Amastin surface glycoprotein DUF4191 PF13829.6 AIO02557.1 - 0.7 9.2 1.9 0.79 9.0 1.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4191) MpPF26 PF07666.11 AIO02557.1 - 1.7 8.7 11.4 0.27 11.3 2.7 2.1 1 1 1 2 2 2 0 M penetrans paralogue family 26 Amastin PF07344.11 AIO02558.1 - 5.1e-14 52.4 6.5 9.8e-14 51.5 6.5 1.5 1 1 0 1 1 1 1 Amastin surface glycoprotein DUF3139 PF11337.8 AIO02558.1 - 1.1 10.0 3.4 0.85 10.3 0.7 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3139) DUF2207 PF09972.9 AIO02558.1 - 2.4 6.9 8.4 0.38 9.5 1.5 2.1 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) TFIIS_C PF01096.18 AIO02559.1 - 1.8e-11 43.7 7.5 1.8e-11 43.7 7.5 2.6 2 1 0 2 2 2 1 Transcription factor S-II (TFIIS) DUF1451 PF07295.11 AIO02559.1 - 0.022 14.8 0.2 0.022 14.8 0.2 2.4 2 1 0 2 2 2 0 Zinc-ribbon containing domain Baculo_LEF5_C PF11792.8 AIO02559.1 - 0.023 14.4 2.5 0.075 12.7 2.5 2.0 1 0 0 1 1 1 0 Baculoviridae late expression factor 5 C-terminal domain DUF678 PF05077.12 AIO02559.1 - 0.075 13.2 3.1 29 4.9 2.3 3.3 2 1 0 2 2 2 0 Protein of unknown function (DUF678) Sp38 PF07354.12 AIO02559.1 - 0.22 10.9 4.1 0.5 9.8 1.3 2.0 2 0 0 2 2 2 0 Zona-pellucida-binding protein (Sp38) ZF-HD_dimer PF04770.12 AIO02559.1 - 0.3 11.5 7.5 14 6.1 0.7 3.5 2 1 1 3 3 3 0 ZF-HD protein dimerisation region RNA_POL_M_15KD PF02150.16 AIO02559.1 - 0.51 10.2 6.0 25 4.9 0.0 3.7 4 0 0 4 4 4 0 RNA polymerases M/15 Kd subunit Phage_lysozyme PF00959.19 AIO02560.1 - 0.036 14.5 0.0 0.15 12.5 0.0 2.2 1 0 0 1 1 1 0 Phage lysozyme Katanin_con80 PF13925.6 AIO02560.1 - 0.15 12.1 6.3 3.1 7.8 1.8 2.8 2 1 1 3 3 3 0 con80 domain of Katanin Lectin_N PF03954.14 AIO02560.1 - 4.5 7.0 9.3 0.23 11.2 2.0 2.5 2 0 0 2 2 2 0 Hepatic lectin, N-terminal domain ADH_zinc_N PF00107.26 AIO02562.1 - 2.3e-28 98.8 0.0 7e-28 97.2 0.0 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 AIO02562.1 - 2e-16 61.2 0.0 4.5e-16 60.1 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 AIO02562.1 - 1.5e-12 47.4 0.0 3.6e-12 46.1 0.0 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Semialdhyde_dh PF01118.24 AIO02562.1 - 0.025 15.0 0.0 0.4 11.1 0.0 2.3 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain TrkA_N PF02254.18 AIO02562.1 - 0.026 14.8 0.0 0.052 13.8 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain Gly_rich_SFCGS PF14272.6 AIO02562.1 - 0.059 13.4 0.2 5.8 7.0 0.0 2.4 2 0 0 2 2 2 0 Glycine-rich SFCGS Glycos_transf_4 PF00953.21 AIO02563.1 - 5.5e-48 163.0 6.0 5.5e-48 163.0 6.0 2.1 2 0 0 2 2 2 1 Glycosyl transferase family 4 DUF2929 PF11151.8 AIO02563.1 - 0.21 11.9 2.3 2.6 8.4 0.2 3.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2929) Sld5 PF05916.11 AIO02564.1 - 2e-17 63.6 0.0 3.6e-17 62.8 0.0 1.4 1 0 0 1 1 1 1 GINS complex protein Urocanase_C PF17392.2 AIO02564.1 - 6.9 6.1 5.8 0.52 9.7 0.5 1.8 2 0 0 2 2 2 0 Urocanase C-terminal domain Arrestin_N PF00339.29 AIO02565.1 - 1.1e-05 25.6 0.0 0.00039 20.5 0.0 2.7 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain LDB19 PF13002.7 AIO02565.1 - 4.3e-05 23.3 0.0 0.00016 21.4 0.0 1.9 2 0 0 2 2 2 1 Arrestin_N terminal like Spo0M PF07070.11 AIO02565.1 - 0.006 16.2 0.2 0.027 14.0 0.1 2.1 2 0 0 2 2 2 1 SpoOM protein Utp21 PF04192.12 AIO02566.1 - 3.9e-25 88.7 0.0 6.2e-25 88.1 0.0 1.2 1 0 0 1 1 1 1 Utp21 specific WD40 associated putative domain WD40 PF00400.32 AIO02566.1 - 7.6e-14 51.9 10.2 0.00081 20.2 0.0 8.8 10 0 0 10 10 10 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 AIO02566.1 - 8.9e-11 42.0 0.1 0.02 15.2 0.0 5.5 5 1 1 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 AIO02566.1 - 0.00029 19.6 1.8 0.039 12.6 0.0 3.7 3 1 1 4 4 4 1 Nucleoporin Nup120/160 Hira PF07569.11 AIO02566.1 - 0.0011 18.8 1.4 0.62 9.7 0.3 3.8 3 1 1 4 4 4 1 TUP1-like enhancer of split PQQ_2 PF13360.6 AIO02566.1 - 0.0018 17.9 5.1 0.23 11.0 0.3 3.1 2 2 0 2 2 2 2 PQQ-like domain PALB2_WD40 PF16756.5 AIO02566.1 - 0.0033 16.4 4.4 0.027 13.4 0.1 3.6 4 0 0 4 4 4 1 Partner and localizer of BRCA2 WD40 domain Utp12 PF04003.12 AIO02566.1 - 0.0071 16.6 0.0 0.017 15.5 0.0 1.6 1 0 0 1 1 1 1 Dip2/Utp12 Family HU-CCDC81_euk_2 PF18289.1 AIO02566.1 - 0.18 12.0 0.0 1.2 9.3 0.0 2.2 2 0 0 2 2 2 0 CCDC81 eukaryotic HU domain 2 LRR_6 PF13516.6 AIO02568.1 - 1.6e-33 111.8 72.3 0.0014 18.6 0.1 21.4 23 1 1 24 24 24 11 Leucine Rich repeat LRR_4 PF12799.7 AIO02568.1 - 1.1e-09 38.5 57.2 0.01 16.3 0.0 14.1 13 2 2 16 16 16 5 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 AIO02568.1 - 0.00014 21.9 26.8 95 4.2 0.0 15.6 19 1 0 19 19 19 0 Leucine Rich Repeat Suppressor_P21 PF11479.8 AIO02568.1 - 0.00071 19.7 2.2 9.5 6.5 0.4 3.9 3 0 0 3 3 3 2 RNA silencing suppressor P21 C-terminal domain AIMP2_LysRS_bd PF16780.5 AIO02568.1 - 0.014 15.1 0.0 0.031 14.0 0.0 1.5 1 0 0 1 1 1 0 AIMP2 lysyl-tRNA synthetase binding domain LRR_2 PF07723.13 AIO02568.1 - 3.4 8.5 10.4 28 5.6 0.0 5.9 6 0 0 6 6 6 0 Leucine Rich Repeat LRR_8 PF13855.6 AIO02568.1 - 3.6 7.4 58.2 1.6 8.5 0.3 13.0 9 6 4 14 14 14 0 Leucine rich repeat WD40 PF00400.32 AIO02569.1 - 1.6e-06 28.7 1.4 0.38 11.7 0.0 5.2 4 0 0 4 4 4 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 AIO02569.1 - 0.024 14.9 0.0 6.8 7.1 0.0 3.2 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain Pkinase PF00069.25 AIO02570.1 - 4.3e-45 154.1 0.0 5.3e-22 78.4 0.0 2.7 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 AIO02570.1 - 9e-16 57.9 0.0 6.1e-09 35.5 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase HEAT PF02985.22 AIO02570.1 - 0.013 15.7 1.1 3.9 8.0 0.2 2.9 2 0 0 2 2 2 0 HEAT repeat Cor1 PF04803.12 AIO02571.1 - 0.92 9.7 17.5 0.17 12.1 9.8 2.6 1 1 0 2 2 2 0 Cor1/Xlr/Xmr conserved region TPR_14 PF13428.6 AIO02573.1 - 8e-11 41.8 53.1 0.014 16.2 0.2 12.4 11 3 3 14 14 12 7 Tetratricopeptide repeat TPR_19 PF14559.6 AIO02573.1 - 2.3e-10 40.8 14.0 0.003 18.0 0.0 6.7 7 1 0 7 7 6 2 Tetratricopeptide repeat HAT PF02184.16 AIO02573.1 - 1.9e-08 34.1 10.2 0.12 12.3 0.1 5.6 5 0 0 5 5 5 3 HAT (Half-A-TPR) repeat TPR_16 PF13432.6 AIO02573.1 - 2.6e-06 28.0 26.2 0.54 10.9 0.1 8.1 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_9 PF13371.6 AIO02573.1 - 0.0027 17.8 0.3 0.0027 17.8 0.3 5.8 6 0 0 6 6 6 1 Tetratricopeptide repeat NRDE-2 PF08424.10 AIO02573.1 - 0.0084 15.3 0.2 0.3 10.1 0.1 3.0 2 1 0 2 2 2 1 NRDE-2, necessary for RNA interference DUF2063 PF09836.9 AIO02573.1 - 0.021 15.0 0.5 0.097 12.9 0.2 2.3 2 0 0 2 2 2 0 Putative DNA-binding domain Mad3_BUB1_I PF08311.12 AIO02573.1 - 0.045 13.7 2.9 18 5.3 0.1 5.3 5 1 0 5 5 5 0 Mad3/BUB1 homology region 1 SchA_CurD PF04486.12 AIO02573.1 - 0.051 13.7 0.1 0.62 10.2 0.1 2.7 2 0 0 2 2 2 0 SchA/CurD like domain TPR_2 PF07719.17 AIO02573.1 - 0.15 12.2 12.3 28 5.1 0.0 7.0 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_6 PF13174.6 AIO02573.1 - 0.8 10.5 17.3 44 5.0 0.6 7.7 8 0 0 8 8 8 0 Tetratricopeptide repeat TPR_7 PF13176.6 AIO02573.1 - 4.6 7.5 10.0 9.3 6.5 0.0 5.5 6 0 0 6 6 6 0 Tetratricopeptide repeat Arf PF00025.21 AIO02574.1 - 2.9e-12 46.4 0.0 5.1e-12 45.6 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family PH PF00169.29 AIO02574.1 - 1.2e-08 35.3 0.0 2.9e-08 34.2 0.0 1.6 1 0 0 1 1 1 1 PH domain MMR_HSR1 PF01926.23 AIO02574.1 - 0.013 15.6 0.0 0.069 13.2 0.0 2.3 2 1 0 2 2 2 0 50S ribosome-binding GTPase PH_8 PF15409.6 AIO02574.1 - 0.017 15.4 0.2 0.087 13.1 0.2 2.3 2 0 0 2 2 2 0 Pleckstrin homology domain C2 PF00168.30 AIO02575.1 - 4.8e-41 139.2 0.0 1.3e-11 44.7 0.0 8.4 9 0 0 9 9 9 6 C2 domain Statherin PF03875.13 AIO02575.1 - 0.59 10.3 2.6 34 4.6 0.1 3.6 3 0 0 3 3 3 0 Statherin C2 PF00168.30 AIO02576.1 - 1.3e-14 54.3 0.0 0.01 16.1 0.1 4.5 4 0 0 4 4 4 4 C2 domain AAA PF00004.29 AIO02579.1 - 6.5e-44 149.6 0.0 1.4e-43 148.5 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 AIO02579.1 - 6.4e-15 54.7 0.3 2e-14 53.1 0.1 2.0 2 0 0 2 2 1 1 AAA+ lid domain AAA_5 PF07728.14 AIO02579.1 - 2.7e-07 30.6 0.1 9.9e-07 28.8 0.1 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 AIO02579.1 - 3.4e-07 30.5 0.3 2.8e-06 27.6 0.0 2.5 3 0 0 3 3 3 1 AAA domain (Cdc48 subfamily) Prot_ATP_ID_OB PF16450.5 AIO02579.1 - 1.3e-06 28.2 1.0 2.9e-06 27.1 1.0 1.6 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_16 PF13191.6 AIO02579.1 - 1.4e-06 28.8 0.4 8.5e-05 23.0 0.0 2.9 2 1 0 3 3 3 1 AAA ATPase domain RuvB_N PF05496.12 AIO02579.1 - 1.8e-05 24.5 0.0 5e-05 23.1 0.0 1.8 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 AIO02579.1 - 2.5e-05 24.6 3.2 0.01 16.1 0.0 3.2 2 1 1 3 3 3 1 AAA domain AAA_18 PF13238.6 AIO02579.1 - 0.0004 20.9 0.2 0.013 16.0 0.0 2.7 3 1 0 3 3 2 1 AAA domain IstB_IS21 PF01695.17 AIO02579.1 - 0.0012 18.6 0.2 0.0033 17.2 0.0 1.8 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_33 PF13671.6 AIO02579.1 - 0.0015 18.7 0.3 0.0033 17.6 0.0 1.9 2 1 0 2 2 1 1 AAA domain ATPase PF06745.13 AIO02579.1 - 0.0025 17.2 0.3 0.1 11.9 0.0 2.6 3 0 0 3 3 3 1 KaiC Sigma54_activat PF00158.26 AIO02579.1 - 0.0029 17.3 0.8 0.052 13.3 0.1 3.2 2 1 0 2 2 2 1 Sigma-54 interaction domain TIP49 PF06068.13 AIO02579.1 - 0.0032 16.7 0.0 0.016 14.4 0.0 2.1 2 0 0 2 2 2 1 TIP49 P-loop domain AAA_28 PF13521.6 AIO02579.1 - 0.0045 17.2 0.2 0.014 15.6 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.6 AIO02579.1 - 0.0063 16.1 0.6 0.17 11.5 0.0 2.8 3 0 0 3 3 3 1 AAA domain AAA_14 PF13173.6 AIO02579.1 - 0.0066 16.5 0.0 0.06 13.4 0.0 2.2 2 0 0 2 2 2 1 AAA domain Mg_chelatase PF01078.21 AIO02579.1 - 0.0074 15.7 0.0 0.027 13.9 0.0 1.9 2 0 0 2 2 1 1 Magnesium chelatase, subunit ChlI NB-ARC PF00931.22 AIO02579.1 - 0.0089 15.2 0.4 0.4 9.8 0.0 2.5 3 0 0 3 3 3 1 NB-ARC domain AAA_3 PF07726.11 AIO02579.1 - 0.01 15.7 0.0 0.025 14.4 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 AIO02579.1 - 0.012 16.0 0.0 0.026 14.9 0.0 1.6 1 0 0 1 1 1 0 RNA helicase DUF815 PF05673.13 AIO02579.1 - 0.012 14.7 0.0 0.056 12.6 0.0 2.0 2 1 0 2 2 2 0 Protein of unknown function (DUF815) TsaE PF02367.17 AIO02579.1 - 0.013 15.5 0.0 0.031 14.3 0.0 1.6 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Zeta_toxin PF06414.12 AIO02579.1 - 0.015 14.6 0.5 0.16 11.3 0.0 2.5 2 1 1 3 3 3 0 Zeta toxin ADIP PF11559.8 AIO02579.1 - 0.015 15.4 1.4 0.031 14.4 1.4 1.4 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding AAA_11 PF13086.6 AIO02579.1 - 0.016 15.0 0.1 0.28 10.9 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 AIO02579.1 - 0.02 14.4 0.0 0.048 13.2 0.0 1.7 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_24 PF13479.6 AIO02579.1 - 0.022 14.5 0.1 0.061 13.0 0.1 1.9 1 1 0 1 1 1 0 AAA domain PhoH PF02562.16 AIO02579.1 - 0.028 13.9 0.1 0.11 12.0 0.0 1.9 2 0 0 2 2 2 0 PhoH-like protein APG6_N PF17675.1 AIO02579.1 - 0.029 14.9 0.3 0.062 13.8 0.3 1.5 1 0 0 1 1 1 0 Apg6 coiled-coil region DUF4618 PF15397.6 AIO02579.1 - 0.046 13.1 1.0 0.12 11.8 1.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4618) Parvo_NS1 PF01057.17 AIO02579.1 - 0.058 12.5 0.0 0.11 11.6 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 DASH_Dad2 PF08654.10 AIO02579.1 - 0.073 13.5 0.5 0.21 12.0 0.5 1.8 1 0 0 1 1 1 0 DASH complex subunit Dad2 Prot_ATP_OB_N PF17758.1 AIO02579.1 - 0.088 12.5 0.1 0.27 10.9 0.1 1.8 1 0 0 1 1 1 0 Proteasomal ATPase OB N-terminal domain AAA_19 PF13245.6 AIO02579.1 - 0.13 12.6 1.3 0.49 10.7 0.0 2.4 2 1 1 3 3 2 0 AAA domain NTPase_1 PF03266.15 AIO02579.1 - 0.27 11.1 2.6 2.9 7.8 0.0 3.2 3 1 0 3 3 3 0 NTPase DUF2968 PF11180.8 AIO02579.1 - 0.42 10.2 4.2 0.28 10.8 2.4 1.6 2 0 0 2 2 1 0 Protein of unknown function (DUF2968) HECT PF00632.25 AIO02580.1 - 7.2e-62 209.6 0.0 1.9e-60 204.9 0.0 2.5 3 0 0 3 3 3 1 HECT-domain (ubiquitin-transferase) L_lactis_RepB_C PF06430.12 AIO02580.1 - 0.15 12.1 0.1 0.3 11.1 0.1 1.4 1 0 0 1 1 1 0 Lactococcus lactis RepB C-terminus HsbA PF12296.8 AIO02580.1 - 0.4 11.1 2.6 6.3 7.3 0.2 3.1 2 0 0 2 2 2 0 Hydrophobic surface binding protein A AOX PF01786.17 AIO02581.1 - 2.9e-81 272.2 0.1 3.5e-81 271.9 0.1 1.1 1 0 0 1 1 1 1 Alternative oxidase GCP_C_terminal PF04130.13 AIO02582.1 - 5.8e-41 141.0 0.6 1.2e-40 140.0 0.6 1.5 1 0 0 1 1 1 1 Gamma tubulin complex component C-terminal GCP_N_terminal PF17681.1 AIO02582.1 - 1e-26 94.3 0.0 2.5e-26 93.0 0.0 1.7 1 1 0 1 1 1 1 Gamma tubulin complex component N-terminal DUF309 PF03745.14 AIO02582.1 - 0.017 14.8 0.2 0.13 12.0 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF309) DEAD PF00270.29 AIO02583.1 - 1.2e-30 106.5 0.0 3.9e-30 104.9 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 AIO02583.1 - 1.4e-29 102.6 0.2 1.9e-28 99.1 0.1 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 AIO02583.1 - 0.0046 17.0 0.0 0.025 14.6 0.0 2.2 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit Peptidase_M16_M PF16187.5 AIO02583.1 - 0.078 12.3 0.1 0.16 11.3 0.1 1.4 1 0 0 1 1 1 0 Middle or third domain of peptidase_M16 Nore1-SARAH PF16517.5 AIO02583.1 - 0.12 12.2 2.3 0.15 12.0 0.1 2.4 2 0 0 2 2 2 0 Novel Ras effector 1 C-terminal SARAH (Sav/Rassf/Hpo) domain AAA_22 PF13401.6 AIO02583.1 - 0.13 12.5 1.6 22 5.3 0.0 3.5 4 0 0 4 4 4 0 AAA domain UvrD-helicase PF00580.21 AIO02583.1 - 0.13 11.8 0.0 0.13 11.8 0.0 2.2 3 0 0 3 3 3 0 UvrD/REP helicase N-terminal domain Z1 PF10593.9 AIO02583.1 - 0.23 10.9 0.0 0.23 10.9 0.0 1.8 2 0 0 2 2 2 0 Z1 domain Stathmin PF00836.19 AIO02584.1 - 0.011 15.7 14.7 0.019 14.9 14.7 1.3 1 0 0 1 1 1 0 Stathmin family Hid1 PF12722.7 AIO02584.1 - 4.3 5.3 6.2 4.6 5.2 6.2 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Ribosomal_L22e PF01776.17 AIO02585.1 - 1.2e-36 125.4 2.8 1.6e-36 125.0 2.8 1.1 1 0 0 1 1 1 1 Ribosomal L22e protein family Asparaginase PF00710.20 AIO02586.1 - 8.4e-36 123.3 0.0 1.1e-35 122.9 0.0 1.2 1 0 0 1 1 1 1 Asparaginase, N-terminal Asparaginase_C PF17763.1 AIO02586.1 - 8.5e-24 84.0 0.1 4e-23 81.8 0.1 1.9 2 0 0 2 2 2 1 Glutaminase/Asparaginase C-terminal domain TPR_19 PF14559.6 AIO02587.1 - 0.00015 22.2 0.1 0.052 14.1 0.1 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.17 AIO02587.1 - 0.0012 18.8 1.3 0.0031 17.5 0.1 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_17 PF13431.6 AIO02587.1 - 0.004 17.4 7.9 0.0096 16.2 0.6 3.6 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_16 PF13432.6 AIO02587.1 - 0.0065 17.1 0.9 0.091 13.4 0.2 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 AIO02587.1 - 0.0079 16.9 1.0 3.1 8.8 0.3 3.1 2 1 1 3 3 3 1 Tetratricopeptide repeat ANAPC3 PF12895.7 AIO02587.1 - 0.015 15.5 1.0 0.44 10.8 0.1 2.7 3 0 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_1 PF00515.28 AIO02587.1 - 0.029 14.2 1.4 0.099 12.5 0.2 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_8 PF13181.6 AIO02587.1 - 0.033 14.4 2.4 0.072 13.3 0.1 2.7 3 0 0 3 3 2 0 Tetratricopeptide repeat TPR_4 PF07721.14 AIO02587.1 - 0.059 14.0 1.9 0.11 13.1 0.8 2.1 2 0 0 2 2 1 0 Tetratricopeptide repeat TPR_12 PF13424.6 AIO02587.1 - 0.065 13.5 0.1 0.24 11.7 0.1 2.0 1 0 0 1 1 1 0 Tetratricopeptide repeat DUF2193 PF09959.9 AIO02587.1 - 0.16 10.4 0.0 0.21 10.0 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2193) Peptidase_M3 PF01432.20 AIO02588.1 - 8.5e-70 236.3 0.1 1.3e-55 189.5 0.2 2.0 2 0 0 2 2 2 2 Peptidase family M3 Peptidase_M32 PF02074.15 AIO02588.1 - 0.0078 15.0 0.4 0.013 14.3 0.4 1.2 1 0 0 1 1 1 1 Carboxypeptidase Taq (M32) metallopeptidase ACP_PD PF04336.12 AIO02589.1 - 0.016 15.6 0.0 0.024 15.0 0.0 1.4 1 0 0 1 1 1 0 Acyl carrier protein phosphodiesterase DnaJ PF00226.31 AIO02590.1 - 2.1e-22 79.0 0.5 7.9e-22 77.2 0.1 2.1 2 0 0 2 2 2 1 DnaJ domain Aa_trans PF01490.18 AIO02591.1 - 1.8e-42 145.5 0.1 2.5e-35 122.0 0.0 2.5 2 1 0 2 2 2 2 Transmembrane amino acid transporter protein MTS PF05175.14 AIO02592.1 - 6.3e-13 48.6 0.1 1e-09 38.2 0.0 2.2 1 1 1 2 2 2 2 Methyltransferase small domain Methyltransf_31 PF13847.6 AIO02592.1 - 2.5e-08 33.9 0.0 6.4e-08 32.5 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 AIO02592.1 - 8.3e-08 32.8 0.0 2.5e-07 31.3 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 AIO02592.1 - 6.4e-07 29.1 0.0 1.4e-06 28.0 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Ubie_methyltran PF01209.18 AIO02592.1 - 0.00033 20.1 0.0 0.00052 19.4 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_11 PF08241.12 AIO02592.1 - 0.0012 19.4 0.0 0.0028 18.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 AIO02592.1 - 0.0037 17.1 0.0 0.015 15.1 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_32 PF13679.6 AIO02592.1 - 0.0059 16.6 0.0 0.011 15.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 AIO02592.1 - 0.0075 17.0 0.0 0.018 15.8 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_16 PF10294.9 AIO02592.1 - 0.0083 15.9 0.0 0.014 15.1 0.0 1.3 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_18 PF12847.7 AIO02592.1 - 0.0084 16.1 0.0 0.016 15.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Met_10 PF02475.16 AIO02592.1 - 0.0094 15.7 0.0 0.015 15.1 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein AviRa PF11599.8 AIO02592.1 - 0.013 14.9 0.0 0.02 14.4 0.0 1.3 1 0 0 1 1 1 0 RRNA methyltransferase AviRa Methyltransf_15 PF09445.10 AIO02592.1 - 0.026 14.1 0.0 0.047 13.3 0.0 1.3 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase TRM PF02005.16 AIO02592.1 - 0.11 11.6 0.0 0.15 11.2 0.0 1.1 1 0 0 1 1 1 0 N2,N2-dimethylguanosine tRNA methyltransferase UPF0020 PF01170.18 AIO02592.1 - 4.2 7.0 4.7 98 2.5 4.7 2.7 1 1 0 1 1 1 0 Putative RNA methylase family UPF0020 DUF2870 PF11069.8 AIO02593.1 - 7.7e-36 122.4 0.5 1.2e-35 121.7 0.1 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF2870) Nup54_C PF18437.1 AIO02593.1 - 0.093 12.6 0.7 0.21 11.5 0.7 1.6 1 0 0 1 1 1 0 Nup54 C-terminal interacting domain Ribosomal_L18 PF17135.4 AIO02594.1 - 2.3e-74 248.9 2.8 2.6e-74 248.7 2.8 1.0 1 0 0 1 1 1 1 Ribosomal protein 60S L18 and 50S L18e Ribosomal_L27A PF00828.19 AIO02594.1 - 0.00046 20.9 0.1 0.0014 19.3 0.1 1.9 1 1 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A ABC1 PF03109.16 AIO02596.1 - 2e-26 92.5 0.0 3.7e-26 91.6 0.0 1.4 1 0 0 1 1 1 1 ABC1 family AalphaY_MDB PF04611.12 AIO02596.1 - 0.019 15.0 0.0 0.037 14.0 0.0 1.4 1 0 0 1 1 1 0 Mating type protein A alpha Y mating type dependent binding region Pkinase PF00069.25 AIO02596.1 - 0.035 13.5 0.0 0.056 12.8 0.0 1.2 1 0 0 1 1 1 0 Protein kinase domain Alpha_kinase PF02816.18 AIO02597.1 - 2.6e-51 174.4 0.3 3.4e-51 174.0 0.3 1.2 1 0 0 1 1 1 1 Alpha-kinase family Alpha_kinase PF02816.18 AIO02598.1 - 7.7e-85 283.7 0.0 3e-42 144.8 0.0 3.2 3 0 0 3 3 3 3 Alpha-kinase family Alpha_kinase PF02816.18 AIO02599.1 - 1.8e-57 194.4 0.7 2.2e-57 194.2 0.7 1.1 1 0 0 1 1 1 1 Alpha-kinase family PSP1 PF04468.12 AIO02600.1 - 7.8e-27 93.4 0.7 1.7e-26 92.3 0.7 1.6 1 0 0 1 1 1 1 PSP1 C-terminal conserved region DASH_Spc34 PF08657.10 AIO02600.1 - 0.0022 17.8 0.6 0.0038 17.1 0.6 1.3 1 0 0 1 1 1 1 DASH complex subunit Spc34 zf-HC5HC2H PF13771.6 AIO02603.1 - 1.9e-09 37.6 3.8 1.9e-09 37.6 3.8 3.1 3 1 0 3 3 3 1 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.6 AIO02603.1 - 2.6e-07 30.8 7.6 2.6e-07 30.8 7.6 3.0 2 2 0 2 2 2 1 PHD-zinc-finger like domain GPW_gp25 PF04965.14 AIO02604.1 - 0.023 14.4 0.0 0.082 12.7 0.0 1.9 1 0 0 1 1 1 0 Gene 25-like lysozyme FliJ PF02050.16 AIO02604.1 - 0.66 10.2 14.8 0.29 11.4 0.3 2.5 2 0 0 2 2 2 0 Flagellar FliJ protein M3 PF09213.10 AIO02605.1 - 0.065 11.9 0.1 0.11 11.2 0.1 1.2 1 0 0 1 1 1 0 M3 Ham1p_like PF01725.16 AIO02606.1 - 4.1e-45 154.0 0.0 4.7e-45 153.8 0.0 1.0 1 0 0 1 1 1 1 Ham1 family Peptidase_S9 PF00326.21 AIO02607.1 - 2.4e-08 33.7 0.2 3.7e-07 29.8 0.1 2.5 2 1 0 2 2 2 1 Prolyl oligopeptidase family Esterase_phd PF10503.9 AIO02607.1 - 6.6e-07 29.0 1.8 3.8e-06 26.6 1.8 2.2 1 1 0 1 1 1 1 Esterase PHB depolymerase Abhydrolase_2 PF02230.16 AIO02607.1 - 1.5e-06 28.2 0.1 3.6e-05 23.7 0.0 2.4 2 1 0 2 2 2 1 Phospholipase/Carboxylesterase Esterase PF00756.20 AIO02607.1 - 0.0017 18.0 0.1 0.012 15.2 0.1 2.1 1 1 0 1 1 1 1 Putative esterase Hydrolase_4 PF12146.8 AIO02607.1 - 0.03 13.6 0.4 9.5 5.4 0.0 3.1 2 1 1 3 3 3 0 Serine aminopeptidase, S33 Peptidase_S15 PF02129.18 AIO02607.1 - 0.032 13.8 0.1 0.5 9.9 0.1 2.5 2 1 1 3 3 3 0 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_1 PF00561.20 AIO02607.1 - 0.035 13.7 0.0 0.38 10.3 0.0 2.2 1 1 1 2 2 2 0 alpha/beta hydrolase fold DUF1100 PF06500.11 AIO02607.1 - 0.039 12.7 0.0 0.06 12.1 0.0 1.1 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1100) DLH PF01738.18 AIO02607.1 - 0.13 11.8 0.0 0.25 10.9 0.0 1.4 1 0 0 1 1 1 0 Dienelactone hydrolase family FSH1 PF03959.13 AIO02607.1 - 0.14 11.8 0.0 0.25 11.0 0.0 1.3 1 0 0 1 1 1 0 Serine hydrolase (FSH1) RL10P_insert PF17777.1 AIO02608.1 - 1.3e-25 89.2 0.0 2.2e-25 88.4 0.0 1.4 1 0 0 1 1 1 1 Insertion domain in 60S ribosomal protein L10P Ribosomal_L10 PF00466.20 AIO02608.1 - 4.5e-19 68.4 0.3 7e-19 67.8 0.3 1.2 1 0 0 1 1 1 1 Ribosomal protein L10 VPS9 PF02204.18 AIO02609.1 - 2.4e-29 101.6 0.0 5.8e-29 100.4 0.0 1.7 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain HALZ PF02183.18 AIO02610.1 - 0.0066 16.7 0.3 0.0066 16.7 0.3 2.4 3 0 0 3 3 2 1 Homeobox associated leucine zipper Golgin_A5 PF09787.9 AIO02610.1 - 0.0073 15.8 5.1 0.04 13.4 4.2 1.7 1 1 1 2 2 2 1 Golgin subfamily A member 5 ZapB PF06005.12 AIO02610.1 - 0.0075 16.7 9.3 0.083 13.4 1.1 2.2 1 1 1 2 2 2 2 Cell division protein ZapB DUF4201 PF13870.6 AIO02610.1 - 0.041 13.6 6.7 0.088 12.5 6.2 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4201) FlxA PF14282.6 AIO02610.1 - 0.053 13.5 3.8 0.089 12.8 0.9 2.1 1 1 1 2 2 2 0 FlxA-like protein Fib_alpha PF08702.10 AIO02610.1 - 0.068 13.4 0.4 0.088 13.0 0.4 1.2 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family Baculo_PEP_C PF04513.12 AIO02610.1 - 0.085 12.9 0.0 0.1 12.7 0.0 1.1 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Bac_luciferase PF00296.20 AIO02610.1 - 0.086 12.3 0.8 0.098 12.1 0.8 1.1 1 0 0 1 1 1 0 Luciferase-like monooxygenase TMF_DNA_bd PF12329.8 AIO02610.1 - 0.1 12.6 6.4 2.6 8.1 0.6 2.3 2 1 0 2 2 2 0 TATA element modulatory factor 1 DNA binding DUF3450 PF11932.8 AIO02610.1 - 0.13 11.6 8.5 0.053 12.8 0.7 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) Cortex-I_coil PF09304.10 AIO02610.1 - 0.14 12.3 8.6 0.28 11.4 2.5 2.1 1 1 1 2 2 2 0 Cortexillin I, coiled coil DUF4094 PF13334.6 AIO02610.1 - 0.18 12.2 1.4 2.2 8.7 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4094) YabA PF06156.13 AIO02610.1 - 0.2 12.3 4.4 0.73 10.5 0.7 2.1 1 1 1 2 2 2 0 Initiation control protein YabA FlaC_arch PF05377.11 AIO02610.1 - 0.22 11.9 2.2 28 5.2 0.4 2.9 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) kleA_kleC PF17383.2 AIO02610.1 - 0.46 10.8 10.7 3.7 7.9 2.5 2.2 1 1 1 2 2 2 0 Uncharacterized KorC regulated protein A Spc7 PF08317.11 AIO02610.1 - 0.55 9.1 8.0 0.67 8.8 8.0 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF4407 PF14362.6 AIO02610.1 - 0.6 9.4 5.9 0.88 8.9 5.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) XhlA PF10779.9 AIO02610.1 - 1.1 9.5 4.9 0.81 9.9 0.3 2.4 2 1 0 2 2 2 0 Haemolysin XhlA bZIP_2 PF07716.15 AIO02610.1 - 2.8 8.1 12.0 2.5 8.2 1.0 2.8 2 1 0 2 2 2 0 Basic region leucine zipper GIT_CC PF16559.5 AIO02610.1 - 3.2 7.7 5.7 1.3 8.9 0.5 2.4 3 0 0 3 3 3 0 GIT coiled-coil Rho guanine nucleotide exchange factor DUF2968 PF11180.8 AIO02610.1 - 3.4 7.3 10.9 64 3.1 10.9 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF2968) CCDC-167 PF15188.6 AIO02610.1 - 4.9 7.6 9.5 28 5.2 0.6 2.1 1 1 1 2 2 2 0 Coiled-coil domain-containing protein 167 DivIC PF04977.15 AIO02610.1 - 5 7.0 10.6 1.8 8.4 1.9 2.5 2 1 1 3 3 3 0 Septum formation initiator SlyX PF04102.12 AIO02610.1 - 5.4 7.7 9.1 5.6 7.7 1.2 2.7 1 1 2 3 3 3 0 SlyX ADIP PF11559.8 AIO02610.1 - 6.1 6.9 11.4 6.8 6.8 2.0 2.1 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding Vir_act_alpha_C PF10400.9 AIO02610.1 - 9.9 6.9 11.9 4.8e+02 1.5 11.9 2.2 1 1 0 1 1 1 0 Virulence activator alpha C-term Cyt-b5 PF00173.28 AIO02611.1 - 3.6e-14 52.6 0.0 4.1e-14 52.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain SopD PF11047.8 AIO02612.1 - 0.15 11.2 0.0 0.27 10.4 0.0 1.3 1 0 0 1 1 1 0 Salmonella outer protein D Abhydrolase_1 PF00561.20 AIO02613.1 - 0.011 15.4 0.0 5.1 6.7 0.0 3.0 3 0 0 3 3 3 0 alpha/beta hydrolase fold WD40 PF00400.32 AIO02614.1 - 8.8e-11 42.2 7.0 0.078 13.9 0.1 5.7 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 AIO02614.1 - 9.3e-09 35.5 0.0 0.42 10.9 0.0 4.4 3 1 0 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Flavodoxin_1 PF00258.25 AIO02615.1 - 1.6e-43 148.4 0.0 2.4e-24 86.1 0.0 5.9 6 0 0 6 6 6 4 Flavodoxin FAD_binding_1 PF00667.20 AIO02615.1 - 3e-17 62.9 0.0 5.6e-17 62.1 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain NAD_binding_1 PF00175.21 AIO02615.1 - 4.5e-11 43.4 0.0 2.8e-10 40.8 0.0 2.4 2 1 0 2 2 2 1 Oxidoreductase NAD-binding domain RabGAP-TBC PF00566.18 AIO02616.1 - 0.046 13.4 0.1 0.13 11.9 0.1 1.7 1 1 0 1 1 1 0 Rab-GTPase-TBC domain AvrM_N PF18247.1 AIO02616.1 - 0.13 12.2 0.2 0.26 11.2 0.2 1.4 1 0 0 1 1 1 0 Flax-rust effector AvrM N-terminal domain CAMSAP_CH PF11971.8 AIO02617.1 - 0.094 12.6 0.0 0.24 11.3 0.0 1.6 1 0 0 1 1 1 0 CAMSAP CH domain PIG-P PF08510.12 AIO02618.1 - 6.4e-28 97.1 1.2 6.4e-28 97.1 1.2 1.6 2 0 0 2 2 2 1 PIG-P Peptidase_U4 PF03419.13 AIO02618.1 - 0.01 15.1 0.0 0.014 14.7 0.0 1.2 1 0 0 1 1 1 0 Sporulation factor SpoIIGA DPM2 PF07297.12 AIO02618.1 - 0.033 14.5 7.2 0.033 14.5 7.2 2.4 2 1 0 2 2 2 0 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) DUF2347 PF09804.9 AIO02619.1 - 0.094 12.3 0.0 0.23 11.0 0.0 1.7 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2347) FAST_1 PF06743.15 AIO02619.1 - 0.14 12.1 0.2 33 4.5 0.0 3.7 3 0 0 3 3 3 0 FAST kinase-like protein, subdomain 1 Retrotran_gag_2 PF14223.6 AIO02620.1 - 0.1 12.3 0.0 0.26 11.0 0.0 1.7 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type DUF1749 PF08538.10 AIO02621.1 - 5.4e-13 48.7 0.1 8.1e-13 48.1 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1749) Spermine_synth PF01564.17 AIO02623.1 - 0.00042 19.8 0.0 0.0007 19.1 0.0 1.3 1 0 0 1 1 1 1 Spermine/spermidine synthase domain Methyltransf_24 PF13578.6 AIO02623.1 - 0.031 15.3 0.0 0.09 13.8 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_30 PF05430.11 AIO02623.1 - 0.042 13.7 0.0 0.089 12.7 0.0 1.5 1 0 0 1 1 1 0 S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_23 PF13489.6 AIO02623.1 - 0.1 12.4 0.0 0.18 11.6 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain PPR_2 PF13041.6 AIO02624.1 - 8e-38 128.4 4.5 2.9e-15 56.2 0.7 5.1 3 1 2 5 5 5 5 PPR repeat family PPR_3 PF13812.6 AIO02624.1 - 1.1e-33 115.1 0.3 1.6e-13 50.5 0.1 5.1 2 1 3 5 5 5 4 Pentatricopeptide repeat domain PPR PF01535.20 AIO02624.1 - 4e-32 108.2 0.7 5.6e-06 26.3 0.0 6.0 6 0 0 6 6 6 5 PPR repeat PPR_1 PF12854.7 AIO02624.1 - 9e-27 92.5 0.1 1.7e-08 34.0 0.1 6.1 6 0 0 6 6 6 5 PPR repeat PPR_long PF17177.4 AIO02624.1 - 1.2e-19 70.5 0.4 8.2e-15 54.7 0.1 2.3 1 1 1 2 2 2 2 Pentacotripeptide-repeat region of PRORP TPR_14 PF13428.6 AIO02624.1 - 4.2e-06 27.1 0.3 15 6.7 0.0 5.7 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_7 PF13176.6 AIO02624.1 - 0.046 13.8 0.0 21 5.4 0.0 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat WD40 PF00400.32 AIO02625.1 - 1.2e-36 124.1 11.0 1.2e-06 29.1 0.1 7.4 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 AIO02625.1 - 1.2e-06 28.7 0.0 2.6 8.4 0.2 5.2 3 1 4 7 7 7 4 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 AIO02625.1 - 0.013 14.8 0.0 0.073 12.4 0.0 2.0 1 1 0 2 2 2 0 WD40-like domain Roc PF08477.13 AIO02626.1 - 0.0013 19.0 0.0 0.016 15.4 0.0 2.2 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase AAA_16 PF13191.6 AIO02626.1 - 0.0061 17.0 0.1 0.015 15.7 0.0 1.7 2 0 0 2 2 2 1 AAA ATPase domain MttA_Hcf106 PF02416.16 AIO02626.1 - 0.18 11.1 0.6 5.9 6.3 0.0 2.4 2 0 0 2 2 2 0 mttA/Hcf106 family LRR_4 PF12799.7 AIO02627.1 - 2.8e-30 103.8 44.7 0.00087 19.6 0.3 14.5 10 4 5 16 16 16 11 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 AIO02627.1 - 7e-09 35.3 32.1 0.00053 19.7 1.8 9.3 4 3 5 10 10 10 2 Leucine rich repeat LRR_6 PF13516.6 AIO02627.1 - 0.00019 21.2 40.6 0.016 15.2 0.3 12.5 15 0 0 15 15 15 3 Leucine Rich repeat LRR_9 PF14580.6 AIO02627.1 - 0.0011 18.5 7.2 1.2 8.7 0.1 4.6 3 2 1 4 4 4 3 Leucine-rich repeat Sec2p PF06428.11 AIO02628.1 - 0.0051 16.7 3.0 0.16 12.0 0.2 2.9 2 0 0 2 2 2 1 GDP/GTP exchange factor Sec2p LXG PF04740.12 AIO02628.1 - 0.0077 16.0 3.3 0.48 10.1 0.1 3.2 3 0 0 3 3 3 1 LXG domain of WXG superfamily FlaC_arch PF05377.11 AIO02628.1 - 0.024 15.0 1.1 7.1 7.1 0.1 2.7 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) DASH_Duo1 PF08651.10 AIO02628.1 - 0.15 11.9 0.7 6.3 6.6 0.1 3.2 3 0 0 3 3 3 0 DASH complex subunit Duo1 CENP-Q PF13094.6 AIO02628.1 - 0.21 11.8 11.7 0.42 10.8 0.3 3.0 3 0 0 3 3 3 0 CENP-Q, a CENPA-CAD centromere complex subunit 2_5_RNA_ligase2 PF13563.6 AIO02629.1 - 0.012 15.5 0.1 0.031 14.2 0.1 1.8 1 1 1 2 2 2 0 2'-5' RNA ligase superfamily DUF1045 PF06299.12 AIO02629.1 - 0.034 14.1 0.0 0.052 13.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1045) AFP PF02420.15 AIO02629.1 - 0.18 12.2 1.0 0.5 10.9 0.1 2.3 2 0 0 2 2 2 0 Insect antifreeze protein repeat MtN3_slv PF03083.16 AIO02630.1 - 8.9e-22 76.9 20.2 3.4e-14 52.7 0.7 2.6 3 0 0 3 3 3 2 Sugar efflux transporter for intercellular exchange DUF1003 PF06210.11 AIO02630.1 - 5.5 7.1 8.0 7 6.8 1.4 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF1003) LRR_9 PF14580.6 AIO02631.1 - 7.5e-14 51.6 0.0 9.6e-11 41.5 0.0 2.2 1 1 0 1 1 1 1 Leucine-rich repeat LRR_4 PF12799.7 AIO02631.1 - 1.2e-12 47.8 11.1 0.00012 22.3 0.3 4.4 3 2 1 4 4 4 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 AIO02631.1 - 3.6e-12 45.9 12.8 5.4e-07 29.3 0.7 3.8 2 1 1 3 3 3 2 Leucine rich repeat LRR_6 PF13516.6 AIO02631.1 - 0.0042 17.0 15.9 0.0099 15.9 0.3 4.9 6 0 0 6 6 6 2 Leucine Rich repeat LRR_1 PF00560.33 AIO02631.1 - 2.6 8.9 14.3 8.8 7.3 0.0 5.8 6 0 0 6 6 6 0 Leucine Rich Repeat RNase_PH PF01138.21 AIO02632.1 - 5.9e-15 55.9 0.4 1.1e-14 55.1 0.4 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 Clathrin PF00637.20 AIO02633.1 - 2.4e-08 34.0 0.2 2.4e-08 34.0 0.2 2.1 3 0 0 3 3 3 1 Region in Clathrin and VPS Vps8 PF12816.7 AIO02633.1 - 0.00015 21.4 0.1 5.5 6.5 0.0 4.0 4 0 0 4 4 4 2 Golgi CORVET complex core vacuolar protein 8 zf-C3HC4_2 PF13923.6 AIO02633.1 - 0.0046 16.8 1.9 0.011 15.5 1.9 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 AIO02633.1 - 0.012 15.9 2.3 0.036 14.4 2.3 1.8 1 0 0 1 1 1 0 Ring finger domain zf-C3H2C3 PF17122.5 AIO02633.1 - 0.11 12.6 1.4 0.31 11.1 1.4 1.7 1 0 0 1 1 1 0 Zinc-finger zf-rbx1 PF12678.7 AIO02633.1 - 0.16 12.3 5.1 0.37 11.1 5.1 1.7 1 0 0 1 1 1 0 RING-H2 zinc finger domain CH PF00307.31 AIO02635.1 - 8e-12 45.3 0.0 1.4e-11 44.5 0.0 1.4 1 0 0 1 1 1 1 Calponin homology (CH) domain IF-2B PF01008.17 AIO02636.1 - 3.1e-71 239.9 0.1 3.6e-71 239.7 0.1 1.0 1 0 0 1 1 1 1 Initiation factor 2 subunit family UPF0029 PF01205.19 AIO02637.1 - 9.7e-29 99.8 0.0 1.6e-28 99.1 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized protein family UPF0029 RWD PF05773.22 AIO02637.1 - 0.015 15.5 1.0 0.14 12.4 1.0 2.2 1 1 0 1 1 1 0 RWD domain ArnB_C PF18677.1 AIO02637.1 - 0.15 12.2 0.8 0.66 10.1 0.1 2.3 3 0 0 3 3 3 0 Archaellum regulatory network B, C-terminal domain 2OG-FeII_Oxy_2 PF13532.6 AIO02638.1 - 3e-07 30.8 0.0 1.6e-06 28.4 0.0 2.2 2 1 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily DnaJ PF00226.31 AIO02640.1 - 5.1e-06 26.5 0.0 1.1e-05 25.4 0.0 1.6 1 0 0 1 1 1 1 DnaJ domain HTH_38 PF13936.6 AIO02640.1 - 0.004 16.9 0.0 0.011 15.5 0.0 1.8 1 0 0 1 1 1 1 Helix-turn-helix domain PSP1 PF04468.12 AIO02641.1 - 0.043 14.1 0.0 0.076 13.3 0.0 1.4 1 0 0 1 1 1 0 PSP1 C-terminal conserved region Tubulin PF00091.25 AIO02642.1 - 0.0025 18.0 0.0 0.004 17.4 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain DUF4041 PF13250.6 AIO02643.1 - 0.1 12.5 0.0 0.19 11.6 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4041) Ribosomal_S2 PF00318.20 AIO02644.1 - 6.9e-29 100.6 0.5 6e-17 61.6 0.2 2.1 1 1 1 2 2 2 2 Ribosomal protein S2 40S_SA_C PF16122.5 AIO02644.1 - 0.0045 18.3 2.3 0.0082 17.5 2.3 1.4 1 0 0 1 1 1 1 40S ribosomal protein SA C-terminus Sulfotransfer_1 PF00685.27 AIO02644.1 - 0.017 14.6 0.0 0.023 14.2 0.0 1.2 1 0 0 1 1 1 0 Sulfotransferase domain Cep57_CLD_2 PF14197.6 AIO02645.1 - 0.0065 16.5 10.9 0.0065 16.5 10.9 10.3 4 3 8 13 13 13 2 Centrosome localisation domain of PPC89 MAP65_ASE1 PF03999.12 AIO02646.1 - 0.00029 19.7 16.4 0.00096 18.0 8.7 2.6 1 1 1 2 2 2 2 Microtubule associated protein (MAP65/ASE1 family) CLZ PF16526.5 AIO02646.1 - 0.0022 18.3 2.3 0.0022 18.3 2.3 4.1 4 1 1 5 5 5 1 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Herpes_BLRF2 PF05812.12 AIO02646.1 - 0.0048 17.0 0.0 0.0048 17.0 0.0 2.6 2 1 0 2 2 2 1 Herpesvirus BLRF2 protein DUF16 PF01519.16 AIO02646.1 - 0.046 14.2 21.5 0.18 12.3 6.7 3.5 2 1 1 3 3 3 0 Protein of unknown function DUF16 Baculo_PEP_C PF04513.12 AIO02646.1 - 0.16 12.0 9.0 4.7 7.2 3.4 3.7 2 1 2 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus Tweety PF04906.13 AIO02646.1 - 0.17 10.5 10.7 2 7.0 4.2 3.3 3 1 0 3 3 3 0 Tweety AIF-MLS PF14962.6 AIO02646.1 - 0.24 11.3 5.4 1.6 8.7 3.3 2.2 2 0 0 2 2 2 0 Mitochondria Localisation Sequence DUF948 PF06103.11 AIO02646.1 - 0.31 11.3 10.0 0.15 12.4 1.6 3.7 3 1 1 4 4 4 0 Bacterial protein of unknown function (DUF948) DUF2894 PF11445.8 AIO02646.1 - 0.57 10.6 12.3 0.15 12.5 8.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2894) HrpA_pilin PF09589.10 AIO02646.1 - 0.65 10.7 3.5 1.9 9.2 2.8 2.2 1 1 1 2 2 2 0 HrpA pilus formation protein Fib_alpha PF08702.10 AIO02646.1 - 0.71 10.1 22.8 0.28 11.4 8.2 3.5 2 1 0 3 3 3 0 Fibrinogen alpha/beta chain family FliD_C PF07195.12 AIO02646.1 - 1.2 8.6 10.7 0.65 9.4 2.2 2.8 3 0 0 3 3 3 0 Flagellar hook-associated protein 2 C-terminus DUF1043 PF06295.12 AIO02646.1 - 1.5 8.8 16.4 3.4 7.7 7.7 3.2 2 1 2 4 4 4 0 Protein of unknown function (DUF1043) TBD PF12845.7 AIO02646.1 - 1.7 8.6 5.7 31 4.6 0.0 4.5 4 1 1 5 5 5 0 TBD domain SPACA9 PF15120.6 AIO02646.1 - 2 8.1 15.2 0.12 12.1 8.8 2.1 2 1 1 3 3 3 0 Sperm acrosome-associated protein 9 IFT20 PF14931.6 AIO02646.1 - 2.1 8.5 17.8 2.4 8.3 0.9 2.7 2 1 0 2 2 2 0 Intraflagellar transport complex B, subunit 20 Prominin PF05478.11 AIO02646.1 - 2.1 6.2 17.3 2.6 5.9 13.2 2.5 1 1 0 2 2 2 0 Prominin Nbl1_Borealin_N PF10444.9 AIO02646.1 - 3.1 7.5 9.6 4 7.2 0.3 3.2 3 0 0 3 3 3 0 Nbl1 / Borealin N terminal DUF2935 PF11155.8 AIO02646.1 - 4 7.8 7.3 5.8 7.3 3.8 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF2935) TPR_MLP1_2 PF07926.12 AIO02646.1 - 4.4 7.4 29.0 1.4 9.0 3.6 3.5 3 1 0 3 3 3 0 TPR/MLP1/MLP2-like protein YojJ PF10372.9 AIO02646.1 - 7.1 6.8 6.7 2.5 8.3 0.5 3.3 4 1 1 5 5 5 0 Bacterial membrane-spanning protein N-terminus GP41 PF00517.17 AIO02646.1 - 7.5 6.4 10.6 0.15 11.9 1.3 2.5 2 1 1 3 3 3 0 Retroviral envelope protein DUF2854 PF11016.8 AIO02646.1 - 7.9 6.4 6.6 2 8.3 0.1 2.9 2 2 0 3 3 3 0 Protein of unknown function (DUF2854) Hexapep PF00132.24 AIO02647.1 - 1.7e-07 30.7 12.2 0.061 13.1 0.2 5.3 3 2 3 6 6 6 5 Bacterial transferase hexapeptide (six repeats) NOB1_Zn_bind PF08772.11 AIO02649.1 - 6.7e-26 90.3 0.1 1.2e-25 89.4 0.1 1.5 1 0 0 1 1 1 1 Nin one binding (NOB1) Zn-ribbon like PIN_6 PF17146.4 AIO02649.1 - 3.9e-22 78.6 0.2 9.2e-22 77.4 0.2 1.7 1 0 0 1 1 1 1 PIN domain of ribonuclease DUF35_N PF12172.8 AIO02649.1 - 0.00091 19.0 0.8 0.0019 18.0 0.8 1.4 1 0 0 1 1 1 1 Rubredoxin-like zinc ribbon domain (DUF35_N) DZR PF12773.7 AIO02649.1 - 0.011 15.8 0.3 0.019 15.0 0.3 1.4 1 0 0 1 1 1 0 Double zinc ribbon zf-NADH-PPase PF09297.11 AIO02649.1 - 9.3 6.0 6.5 23 4.7 1.5 2.6 2 0 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain CK_II_beta PF01214.18 AIO02652.1 - 5.2e-74 248.0 0.0 6.7e-74 247.6 0.0 1.1 1 0 0 1 1 1 1 Casein kinase II regulatory subunit HU-CCDC81_euk_2 PF18289.1 AIO02654.1 - 1.4e-16 60.4 0.0 3.5e-16 59.1 0.0 1.7 1 0 0 1 1 1 1 CCDC81 eukaryotic HU domain 2 HU-CCDC81_euk_1 PF14908.6 AIO02654.1 - 6e-14 52.0 0.2 9.3e-14 51.4 0.2 1.3 1 0 0 1 1 1 1 CCDC81 eukaryotic HU domain 1 Ribosomal_S2 PF00318.20 AIO02655.1 - 6.9e-29 100.6 0.5 6e-17 61.6 0.2 2.1 1 1 1 2 2 2 2 Ribosomal protein S2 40S_SA_C PF16122.5 AIO02655.1 - 0.0045 18.3 2.3 0.0082 17.5 2.3 1.4 1 0 0 1 1 1 1 40S ribosomal protein SA C-terminus Sulfotransfer_1 PF00685.27 AIO02655.1 - 0.017 14.6 0.0 0.023 14.2 0.0 1.2 1 0 0 1 1 1 0 Sulfotransferase domain Porin_3 PF01459.22 AIO02656.1 - 3e-05 23.6 0.1 0.4 10.1 0.1 2.9 2 1 0 2 2 2 2 Eukaryotic porin VHS PF00790.19 AIO02657.1 - 1.1e-08 35.0 0.0 2.5e-08 33.9 0.0 1.5 1 0 0 1 1 1 1 VHS domain Kinesin PF00225.23 AIO02658.1 - 2.9e-25 88.9 10.3 4.1e-19 68.7 0.0 3.3 3 1 0 3 3 3 2 Kinesin motor domain Microtub_bd PF16796.5 AIO02658.1 - 3.6e-07 30.2 0.0 3.6e-07 30.2 0.0 3.1 3 1 0 3 3 3 1 Microtubule binding MA3 PF02847.17 AIO02659.1 - 1.1e-12 47.9 2.2 1.3e-12 47.7 0.4 2.0 2 0 0 2 2 2 1 MA3 domain MIF4G PF02854.19 AIO02659.1 - 4.7e-05 23.1 1.9 0.00014 21.5 0.1 2.4 2 1 1 3 3 3 1 MIF4G domain DUF3400 PF11880.8 AIO02659.1 - 0.097 12.2 0.1 6.2 6.4 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3400) VPS28 PF03997.12 AIO02660.1 - 1.7e-44 151.8 0.0 2e-44 151.6 0.0 1.0 1 0 0 1 1 1 1 VPS28 protein Aldedh PF00171.22 AIO02661.1 - 1.3e-126 422.8 1.0 1.5e-126 422.7 1.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family SNF2_N PF00176.23 AIO02662.1 - 7e-62 209.2 0.0 1.3e-61 208.3 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 AIO02662.1 - 3.7e-18 65.9 0.0 1.2e-17 64.3 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 AIO02662.1 - 5.6e-09 36.2 0.0 1.2e-08 35.2 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 AIO02662.1 - 0.00016 21.5 0.0 0.00033 20.5 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase ERCC3_RAD25_C PF16203.5 AIO02662.1 - 0.014 14.6 2.8 0.022 14.0 0.0 2.5 3 0 0 3 3 3 0 ERCC3/RAD25/XPB C-terminal helicase Sec8_exocyst PF04048.14 AIO02662.1 - 0.16 11.9 0.0 0.42 10.5 0.0 1.6 1 0 0 1 1 1 0 Sec8 exocyst complex component specific domain WD40 PF00400.32 AIO02663.1 - 0.17 12.8 14.8 3.4 8.7 0.2 7.4 8 0 0 8 8 8 0 WD domain, G-beta repeat PQQ_3 PF13570.6 AIO02663.1 - 2.2 8.9 5.1 4.4 7.9 0.2 4.2 4 0 0 4 4 4 0 PQQ-like domain Phosphonate-bd PF12974.7 AIO02665.1 - 0.042 13.4 0.0 0.1 12.2 0.0 1.6 1 0 0 1 1 1 0 ABC transporter, phosphonate, periplasmic substrate-binding protein NDUF_B12 PF08122.12 AIO02665.1 - 0.32 11.1 4.6 6.3 6.9 0.4 3.3 3 1 1 4 4 4 0 NADH-ubiquinone oxidoreductase B12 subunit family Glyco_hydro_65m PF03632.15 AIO02666.1 - 2.8e-68 230.5 0.0 5e-68 229.7 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 65 central catalytic domain Glyco_hydro_65N PF03636.15 AIO02666.1 - 3.7e-26 92.2 0.4 7.4e-26 91.2 0.4 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 65, N-terminal domain Glyco_hydro_65C PF03633.15 AIO02666.1 - 4.2e-06 26.6 0.0 9.5e-06 25.4 0.0 1.7 1 0 0 1 1 1 1 Glycosyl hydrolase family 65, C-terminal domain HAD_2 PF13419.6 AIO02666.1 - 0.00057 20.0 0.0 0.0011 19.1 0.0 1.4 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase JAKMIP_CC3 PF16034.5 AIO02667.1 - 0.0066 16.4 5.2 0.0066 16.4 5.2 4.3 6 1 0 6 6 6 1 JAKMIP CC3 domain APP_E2 PF12925.7 AIO02667.1 - 0.092 12.4 5.7 0.26 11.0 5.7 1.7 1 0 0 1 1 1 0 E2 domain of amyloid precursor protein Tropomyosin_1 PF12718.7 AIO02667.1 - 0.35 11.0 9.2 5.1 7.3 3.7 3.1 2 0 0 2 2 2 0 Tropomyosin like ADIP PF11559.8 AIO02667.1 - 0.36 10.9 11.4 5.8 7.0 7.5 2.8 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding ERM PF00769.19 AIO02667.1 - 0.61 9.9 19.9 0.082 12.7 12.4 3.0 3 0 0 3 3 3 0 Ezrin/radixin/moesin family WXG100 PF06013.12 AIO02667.1 - 0.93 9.8 5.6 1.7 9.0 0.0 3.6 3 0 0 3 3 3 0 Proteins of 100 residues with WXG RPW8 PF05659.11 AIO02667.1 - 1.5 8.5 9.2 8.6 6.0 1.5 3.9 4 0 0 4 4 4 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 Mod_r PF07200.13 AIO02667.1 - 3.3 7.8 11.7 1.6 8.8 4.9 3.5 3 0 0 3 3 3 0 Modifier of rudimentary (Mod(r)) protein DUF4763 PF15960.5 AIO02667.1 - 6.5 6.0 12.5 1.4 8.1 0.0 3.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4763) IFP_35_N PF07334.13 AIO02668.1 - 0.43 10.7 3.4 3.1 7.9 0.2 2.9 2 0 0 2 2 2 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus MRF_C1 PF13887.6 AIO02668.1 - 0.58 9.4 2.6 45 3.3 0.1 3.5 3 0 0 3 3 3 0 Myelin gene regulatory factor -C-terminal domain 1 Adaptin_N PF01602.20 AIO02669.1 - 1.2e-78 265.0 0.0 1.5e-78 264.7 0.0 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 AIO02669.1 - 6.8e-15 55.5 0.6 1.6e-14 54.3 0.3 1.8 2 0 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 AIO02669.1 - 2e-06 28.1 6.3 2.1e-05 24.8 2.4 3.9 2 2 2 4 4 4 2 HEAT repeats HEAT PF02985.22 AIO02669.1 - 1e-05 25.3 3.9 0.31 11.4 0.3 4.4 3 0 0 3 3 3 3 HEAT repeat HEAT_EZ PF13513.6 AIO02669.1 - 1.3 9.6 5.6 4.1 8.0 1.0 3.1 1 1 2 3 3 3 0 HEAT-like repeat Exo_endo_phos PF03372.23 AIO02670.1 - 1.5e-08 34.5 0.0 9.6e-07 28.6 0.0 2.6 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.6 AIO02670.1 - 0.027 14.3 0.0 0.1 12.5 0.0 2.0 2 0 0 2 2 2 0 Endonuclease-reverse transcriptase DUF737 PF05300.11 AIO02672.1 - 0.41 11.0 9.8 0.72 10.2 9.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF737) GST_C_2 PF13410.6 AIO02675.1 - 2.5e-07 30.6 0.0 1e-06 28.7 0.0 2.1 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 AIO02675.1 - 0.00046 20.3 0.0 0.00096 19.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain SR-25 PF10500.9 AIO02676.1 - 2.2 7.9 13.5 4.2 6.9 13.5 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF244 PF03112.14 AIO02677.1 - 2.2 8.1 6.6 11 5.8 0.4 3.0 2 1 1 3 3 3 0 Uncharacterized protein family (ORF7) DUF DUF4986 PF16375.5 AIO02677.1 - 2.2 9.0 5.0 9.5 7.0 0.2 4.0 3 0 0 3 3 3 0 Domain of unknown function Pcc1 PF09341.10 AIO02677.1 - 2.5 8.3 9.2 0.57 10.4 1.3 3.8 3 1 0 3 3 3 0 Transcription factor Pcc1 Pkinase PF00069.25 AIO02678.1 - 3.2e-57 193.9 0.0 5e-57 193.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 AIO02678.1 - 1.1e-35 123.1 0.2 2.2e-35 122.2 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 AIO02678.1 - 6.2e-10 38.9 0.1 7.2e-08 32.1 0.0 2.6 3 0 0 3 3 3 1 Kinase-like APH PF01636.23 AIO02678.1 - 0.00016 21.7 0.0 0.12 12.3 0.0 3.3 2 1 1 3 3 3 1 Phosphotransferase enzyme family C1_2 PF03107.16 AIO02678.1 - 0.0014 18.9 3.8 0.0014 18.9 3.8 2.1 2 0 0 2 2 2 1 C1 domain Kdo PF06293.14 AIO02678.1 - 0.0076 15.6 0.0 0.016 14.6 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.11 AIO02678.1 - 0.021 13.9 0.0 0.038 13.1 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 FYVE_2 PF02318.16 AIO02678.1 - 0.069 13.4 4.9 0.19 12.0 4.9 1.7 1 0 0 1 1 1 0 FYVE-type zinc finger zf-piccolo PF05715.13 AIO02678.1 - 0.14 12.3 4.9 0.31 11.2 4.9 1.6 1 0 0 1 1 1 0 Piccolo Zn-finger Haspin_kinase PF12330.8 AIO02678.1 - 0.19 10.7 0.0 0.3 10.0 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain zf-UDP PF14569.6 AIO02678.1 - 4.4 7.5 7.6 8.3 6.6 6.1 2.1 2 0 0 2 2 2 0 Zinc-binding RING-finger zf_C2H2_ZHX PF18387.1 AIO02678.1 - 5.8 6.6 5.8 1.9 8.2 0.0 2.8 2 1 0 2 2 2 0 Zinc-fingers and homeoboxes C2H2 finger domain Ubie_methyltran PF01209.18 AIO02679.1 - 3.9e-107 356.9 0.0 4.5e-107 356.7 0.0 1.0 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.6 AIO02679.1 - 3.5e-16 59.7 0.1 1.5e-15 57.7 0.1 2.1 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 AIO02679.1 - 5.3e-16 59.0 0.0 1e-15 58.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 AIO02679.1 - 1.4e-09 37.9 0.0 2.2e-09 37.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 AIO02679.1 - 2.9e-07 31.2 0.0 4.5e-07 30.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 AIO02679.1 - 4.5e-05 23.3 0.0 7.3e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.15 AIO02679.1 - 0.00029 20.8 0.0 0.022 14.6 0.0 2.6 2 1 1 3 3 3 1 Hypothetical methyltransferase WD40 PF00400.32 AIO02680.1 - 0.067 14.1 3.3 2.3 9.2 0.0 3.4 3 0 0 3 3 3 0 WD domain, G-beta repeat Y_phosphatase PF00102.27 AIO02681.1 - 2.9e-63 213.6 0.0 4.3e-63 213.0 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.20 AIO02681.1 - 0.00031 20.6 1.5 0.00069 19.4 0.0 2.3 3 0 0 3 3 3 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 AIO02681.1 - 0.00047 20.2 0.0 0.001 19.1 0.0 1.5 1 0 0 1 1 1 1 Tyrosine phosphatase family PTPlike_phytase PF14566.6 AIO02681.1 - 0.019 15.1 0.0 0.052 13.7 0.0 1.8 1 0 0 1 1 1 0 Inositol hexakisphosphate Pyr_redox_2 PF07992.14 AIO02682.1 - 9.4e-54 182.6 0.0 1.2e-53 182.3 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 AIO02682.1 - 8.1e-13 48.8 0.0 1.8e-08 34.8 0.1 2.7 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 AIO02682.1 - 7.3e-06 25.3 0.0 0.0052 15.9 0.0 2.7 3 0 0 3 3 3 2 FAD binding domain NAD_binding_8 PF13450.6 AIO02682.1 - 7.6e-06 26.1 0.0 0.2 11.9 0.0 2.5 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain DAO PF01266.24 AIO02682.1 - 0.00021 21.0 0.1 0.58 9.7 0.0 3.2 2 1 1 3 3 3 2 FAD dependent oxidoreductase GIDA PF01134.22 AIO02682.1 - 0.0026 16.9 0.0 1 8.3 0.0 3.1 3 0 0 3 3 3 1 Glucose inhibited division protein A Lycopene_cycl PF05834.12 AIO02682.1 - 0.0095 15.0 0.2 3.6 6.5 0.0 3.0 3 0 0 3 3 3 1 Lycopene cyclase protein Pyr_redox_3 PF13738.6 AIO02682.1 - 0.015 14.6 0.0 3.3 6.9 0.0 3.1 4 0 0 4 4 4 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 AIO02682.1 - 0.043 12.7 0.0 12 4.6 0.0 2.8 2 1 1 3 3 3 0 Tryptophan halogenase NAD_binding_7 PF13241.6 AIO02682.1 - 0.08 13.4 0.4 4.8 7.7 0.0 3.2 3 1 0 3 3 3 0 Putative NAD(P)-binding HI0933_like PF03486.14 AIO02682.1 - 0.14 10.8 0.0 6.2 5.4 0.0 2.5 2 0 0 2 2 2 0 HI0933-like protein Pribosyltran_N PF13793.6 AIO02683.1 - 9.9e-40 135.1 0.2 3e-39 133.6 0.0 1.9 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.6 AIO02683.1 - 1.3e-30 106.8 1.5 2.6e-30 105.8 0.8 1.8 1 1 1 2 2 2 1 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.27 AIO02683.1 - 3.9e-16 59.0 0.2 9.3e-16 57.7 0.2 1.6 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.6 AIO02683.1 - 0.00043 19.8 0.1 0.001 18.6 0.1 1.6 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase IL2 PF00715.17 AIO02683.1 - 0.11 12.4 0.0 0.24 11.3 0.0 1.5 1 0 0 1 1 1 0 Interleukin 2 BCS1_N PF08740.11 AIO02684.1 - 1.7e-29 103.1 0.9 3.1e-29 102.3 0.9 1.4 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.29 AIO02684.1 - 2e-11 44.4 0.0 1.4e-05 25.5 0.0 2.8 2 1 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 AIO02684.1 - 0.00034 21.0 0.5 0.0018 18.7 0.5 2.4 1 1 0 1 1 1 1 AAA ATPase domain RuvB_N PF05496.12 AIO02684.1 - 0.0013 18.5 0.0 0.0023 17.7 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 AIO02684.1 - 0.0022 18.0 0.0 0.0048 16.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_11 PF13086.6 AIO02684.1 - 0.011 15.5 0.0 0.026 14.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 AIO02684.1 - 0.012 15.8 0.0 0.012 15.8 0.0 2.3 2 0 0 2 2 1 0 AAA domain TIP49 PF06068.13 AIO02684.1 - 0.031 13.5 0.0 0.054 12.7 0.0 1.2 1 0 0 1 1 1 0 TIP49 P-loop domain AAA_18 PF13238.6 AIO02684.1 - 0.072 13.6 0.0 0.25 11.9 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_3 PF07726.11 AIO02684.1 - 0.078 12.8 0.0 0.23 11.3 0.0 1.7 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) ATPase PF06745.13 AIO02684.1 - 0.11 11.8 0.0 0.24 10.7 0.0 1.5 1 0 0 1 1 1 0 KaiC AAA_6 PF12774.7 AIO02684.1 - 0.18 10.8 0.0 0.27 10.2 0.0 1.2 1 0 0 1 1 1 0 Hydrolytic ATP binding site of dynein motor region DUF5549 PF17703.1 AIO02684.1 - 3.2 7.4 5.7 17 5.0 0.0 2.6 2 0 0 2 2 2 0 Family of unknown function (DUF5549) AIRS_C PF02769.22 AIO02685.1 - 6e-19 68.7 0.0 1.4e-18 67.5 0.0 1.6 1 1 0 1 1 1 1 AIR synthase related protein, C-terminal domain AIRS PF00586.24 AIO02685.1 - 1.9e-09 38.0 0.3 5.4e-09 36.6 0.3 1.7 1 0 0 1 1 1 1 AIR synthase related protein, N-terminal domain Extensin-like_C PF06904.12 AIO02685.1 - 0.038 14.0 0.0 0.07 13.2 0.0 1.4 1 0 0 1 1 1 0 Extensin-like protein C-terminus SF1-HH PF16275.5 AIO02686.1 - 7.5e-07 29.5 0.1 1.8e-06 28.3 0.1 1.7 1 0 0 1 1 1 1 Splicing factor 1 helix-hairpin domain KH_1 PF00013.29 AIO02686.1 - 9e-06 25.4 0.0 1.9e-05 24.4 0.0 1.5 1 0 0 1 1 1 1 KH domain TylF PF05711.11 AIO02687.1 - 1.5e-17 63.8 0.0 8.1e-17 61.3 0.0 2.0 1 1 0 1 1 1 1 Macrocin-O-methyltransferase (TylF) Methyltransf_24 PF13578.6 AIO02687.1 - 1.6e-06 29.1 0.1 7.4e-06 26.9 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain CmcI PF04989.12 AIO02687.1 - 0.0069 16.1 0.0 0.016 14.9 0.0 1.6 1 0 0 1 1 1 1 Cephalosporin hydroxylase SEP PF08059.13 AIO02688.1 - 8.1e-09 35.9 0.0 2.2e-08 34.5 0.0 1.7 1 0 0 1 1 1 1 SEP domain UBX PF00789.20 AIO02688.1 - 0.00018 21.6 0.0 0.00042 20.5 0.0 1.7 1 0 0 1 1 1 1 UBX domain OmpH PF03938.14 AIO02688.1 - 0.01 16.2 3.4 0.021 15.1 3.4 1.4 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) ATG16 PF08614.11 AIO02688.1 - 0.02 15.2 9.8 0.047 13.9 9.8 1.6 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) FPP PF05911.11 AIO02688.1 - 0.025 12.8 5.9 0.036 12.3 5.9 1.2 1 0 0 1 1 1 0 Filament-like plant protein, long coiled-coil IFT57 PF10498.9 AIO02688.1 - 0.025 13.6 1.9 0.039 12.9 1.9 1.2 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 CALCOCO1 PF07888.11 AIO02688.1 - 0.03 13.2 5.6 0.045 12.6 5.6 1.2 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like Jnk-SapK_ap_N PF09744.9 AIO02688.1 - 0.044 14.0 8.2 0.08 13.2 8.2 1.3 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 tRNA-synt_1d PF00750.19 AIO02688.1 - 0.046 12.7 1.9 0.069 12.1 1.9 1.2 1 0 0 1 1 1 0 tRNA synthetases class I (R) DUF4407 PF14362.6 AIO02688.1 - 0.056 12.8 4.2 0.11 11.8 4.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) HMG_box PF00505.19 AIO02688.1 - 0.096 13.1 0.3 0.19 12.2 0.3 1.5 1 0 0 1 1 1 0 HMG (high mobility group) box Spc24 PF08286.11 AIO02688.1 - 0.14 12.5 5.7 0.28 11.4 5.7 1.6 1 0 0 1 1 1 0 Spc24 subunit of Ndc80 Herpes_US12 PF05363.12 AIO02688.1 - 0.3 11.8 1.7 17 6.3 0.3 2.8 2 0 0 2 2 2 0 Herpesvirus US12 family Cep57_MT_bd PF06657.13 AIO02688.1 - 0.36 11.3 6.0 0.79 10.2 6.0 1.6 1 0 0 1 1 1 0 Centrosome microtubule-binding domain of Cep57 Golgin_A5 PF09787.9 AIO02688.1 - 0.41 10.1 6.6 0.72 9.3 6.6 1.3 1 0 0 1 1 1 0 Golgin subfamily A member 5 Ax_dynein_light PF10211.9 AIO02688.1 - 0.65 9.9 5.3 1.3 8.9 5.3 1.5 1 0 0 1 1 1 0 Axonemal dynein light chain V_ATPase_I PF01496.19 AIO02688.1 - 0.88 7.4 2.8 1.3 6.8 2.8 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family TMF_TATA_bd PF12325.8 AIO02688.1 - 1.2 9.4 7.8 5.3 7.3 7.8 2.1 1 1 0 1 1 1 0 TATA element modulatory factor 1 TATA binding APG6_N PF17675.1 AIO02688.1 - 1.4 9.5 14.2 1.3 9.5 12.9 1.6 2 0 0 2 2 1 0 Apg6 coiled-coil region RuvX PF03652.15 AIO02689.1 - 0.054 13.9 0.0 0.099 13.0 0.0 1.3 1 0 0 1 1 1 0 Holliday junction resolvase DAO PF01266.24 AIO02690.1 - 3.7e-44 151.7 0.1 4.5e-44 151.5 0.1 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 AIO02690.1 - 0.00021 21.5 0.2 0.00051 20.2 0.2 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 AIO02690.1 - 0.0012 18.2 0.0 0.0039 16.5 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 AIO02690.1 - 0.0015 17.9 0.2 0.005 16.1 0.0 1.9 2 0 0 2 2 2 1 Thi4 family Mqo PF06039.15 AIO02690.1 - 0.0021 16.7 0.0 0.022 13.3 0.0 2.1 2 0 0 2 2 2 1 Malate:quinone oxidoreductase (Mqo) TrkA_N PF02254.18 AIO02690.1 - 0.0091 16.3 0.2 0.019 15.2 0.2 1.5 1 0 0 1 1 1 1 TrkA-N domain FAD_binding_3 PF01494.19 AIO02690.1 - 0.016 14.5 0.6 0.14 11.4 0.2 2.1 2 0 0 2 2 2 0 FAD binding domain Pyr_redox PF00070.27 AIO02690.1 - 0.06 13.9 0.1 0.21 12.2 0.1 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 AIO02690.1 - 0.12 11.5 0.1 0.19 10.7 0.1 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein NifQ PF04891.12 AIO02691.1 - 5.6 7.3 16.4 3.7 7.9 1.9 4.2 4 1 0 4 4 4 0 NifQ HlyIII PF03006.20 AIO02694.1 - 1.3e-50 172.2 26.6 1.7e-50 171.9 26.6 1.1 1 0 0 1 1 1 1 Haemolysin-III related DUF962 PF06127.11 AIO02694.1 - 0.075 13.1 2.6 0.45 10.6 2.4 2.6 1 1 0 1 1 1 0 Protein of unknown function (DUF962) HlyIII PF03006.20 AIO02695.1 - 2e-52 178.2 25.7 2.4e-52 177.9 25.7 1.1 1 0 0 1 1 1 1 Haemolysin-III related HlyIII PF03006.20 AIO02696.1 - 6.7e-53 179.7 27.2 8.2e-53 179.4 27.2 1.1 1 0 0 1 1 1 1 Haemolysin-III related TMEM238 PF15125.6 AIO02696.1 - 0.038 14.2 0.6 0.038 14.2 0.6 3.0 3 2 1 4 4 4 0 TMEM238 protein family PCIF1_WW PF12237.8 AIO02697.1 - 2.2e-28 99.0 0.4 2.5e-18 66.3 0.2 2.3 2 0 0 2 2 2 2 Phosphorylated CTD interacting factor 1 WW domain AAA_16 PF13191.6 AIO02698.1 - 0.051 14.0 0.0 0.051 14.0 0.0 2.8 2 1 0 2 2 2 0 AAA ATPase domain KTI12 PF08433.10 AIO02698.1 - 0.1 12.0 0.3 1.7 8.1 0.0 2.4 3 0 0 3 3 3 0 Chromatin associated protein KTI12 AAA_29 PF13555.6 AIO02698.1 - 0.14 12.0 0.0 0.37 10.6 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_33 PF13671.6 AIO02698.1 - 0.26 11.4 6.1 0.44 10.7 1.0 3.4 1 1 2 3 3 3 0 AAA domain PAP_RNA-bind PF04926.15 AIO02699.1 - 0.037 13.7 0.0 0.081 12.6 0.0 1.5 1 0 0 1 1 1 0 Poly(A) polymerase predicted RNA binding domain Peptidase_M24 PF00557.24 AIO02700.1 - 2.9e-35 121.9 0.1 4.7e-35 121.2 0.1 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.16 AIO02700.1 - 8.9e-10 38.4 0.0 2.3e-09 37.0 0.0 1.7 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain EMP24_GP25L PF01105.24 AIO02701.1 - 3.4e-12 46.7 0.0 4.5e-12 46.3 0.0 1.3 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD DUF3455 PF11937.8 AIO02702.1 - 0.076 13.4 0.1 0.22 11.9 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3455) HrpB2 PF09487.10 AIO02702.1 - 0.081 13.4 0.0 0.27 11.7 0.0 1.9 2 0 0 2 2 2 0 Bacterial type III secretion protein (HrpB2) HA PF03457.14 AIO02702.1 - 0.085 13.2 0.1 0.22 11.9 0.0 1.7 2 0 0 2 2 2 0 Helicase associated domain Transcript_VP30 PF11507.8 AIO02702.1 - 0.12 12.4 0.0 0.23 11.6 0.0 1.4 1 0 0 1 1 1 0 Ebola virus-specific transcription factor VP30 CAP_C PF08603.11 AIO02703.1 - 1.5e-46 157.9 3.3 1.8e-46 157.6 3.3 1.1 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) C terminal CAP_N PF01213.19 AIO02703.1 - 1.4e-14 54.4 0.9 2.1e-14 53.7 0.9 1.3 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) N terminal TBCC PF07986.12 AIO02703.1 - 2.4e-05 24.0 7.2 4e-05 23.3 7.2 1.3 1 0 0 1 1 1 1 Tubulin binding cofactor C NERD PF08378.11 AIO02705.1 - 1e-16 61.4 0.6 3.4e-16 59.6 0.6 1.9 1 1 0 1 1 1 1 Nuclease-related domain DUF3025 PF11227.8 AIO02705.1 - 0.15 11.9 2.0 0.42 10.4 1.7 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF3025) tRNA-synt_1 PF00133.22 AIO02706.1 - 1.7e-213 710.2 2.6 6.1e-213 708.4 0.1 2.6 2 1 0 2 2 2 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 AIO02706.1 - 6.1e-21 75.0 0.0 2.1e-20 73.2 0.0 1.9 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 AIO02706.1 - 1.7e-13 50.1 2.4 0.0002 20.2 0.2 4.0 3 1 0 3 3 3 3 tRNA synthetases class I (M) tRNA-synt_1e PF01406.19 AIO02706.1 - 0.0013 18.2 0.5 0.068 12.5 0.0 3.0 2 1 1 3 3 3 1 tRNA synthetases class I (C) catalytic domain GAT PF03127.14 AIO02706.1 - 0.17 12.2 0.4 0.4 11.0 0.4 1.6 1 0 0 1 1 1 0 GAT domain Gamma_PGA_hydro PF05908.11 AIO02707.1 - 0.14 11.6 0.4 0.31 10.4 0.2 1.5 1 1 1 2 2 2 0 Poly-gamma-glutamate hydrolase Cyclin_N PF00134.23 AIO02708.1 - 0.00018 21.3 0.1 0.0017 18.1 0.0 2.4 2 1 0 2 2 2 1 Cyclin, N-terminal domain E1_UFD PF09358.10 AIO02709.1 - 0.068 13.9 0.0 1.9 9.2 0.0 2.3 2 0 0 2 2 2 0 Ubiquitin fold domain SUKH-4 PF14435.6 AIO02709.1 - 0.1 12.6 0.1 0.18 11.9 0.1 1.4 1 0 0 1 1 1 0 SUKH-4 immunity protein DAO PF01266.24 AIO02710.1 - 7.3e-18 65.3 4.9 1.4e-07 31.5 0.5 3.8 4 0 0 4 4 4 3 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 AIO02710.1 - 1.4e-07 31.7 0.2 4.2e-07 30.1 0.2 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 AIO02710.1 - 3e-06 26.7 0.1 5.2e-05 22.6 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 AIO02710.1 - 8.2e-06 26.3 0.5 2.5e-05 24.8 0.5 1.8 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 AIO02710.1 - 0.00042 19.5 0.2 0.001 18.2 0.2 1.6 2 0 0 2 2 2 1 Glucose inhibited division protein A Thi4 PF01946.17 AIO02710.1 - 0.00087 18.6 0.1 0.0018 17.6 0.1 1.4 1 0 0 1 1 1 1 Thi4 family AlaDh_PNT_C PF01262.21 AIO02710.1 - 0.0069 15.7 0.4 0.013 14.8 0.4 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_2 PF00890.24 AIO02710.1 - 0.0073 15.4 1.4 0.012 14.8 1.4 1.3 1 0 0 1 1 1 1 FAD binding domain 3HCDH_N PF02737.18 AIO02710.1 - 0.012 15.5 0.3 0.026 14.4 0.3 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain HI0933_like PF03486.14 AIO02710.1 - 0.024 13.4 0.4 0.036 12.8 0.4 1.2 1 0 0 1 1 1 0 HI0933-like protein Pyr_redox_3 PF13738.6 AIO02710.1 - 0.036 13.3 0.0 0.075 12.3 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 AIO02710.1 - 0.046 13.0 0.5 0.092 12.0 0.5 1.4 1 0 0 1 1 1 0 FAD binding domain NAD_binding_9 PF13454.6 AIO02710.1 - 0.054 13.5 0.3 0.12 12.4 0.3 1.6 1 0 0 1 1 1 0 FAD-NAD(P)-binding FAD_oxidored PF12831.7 AIO02710.1 - 0.085 12.2 0.6 0.23 10.8 0.3 1.8 2 0 0 2 2 2 0 FAD dependent oxidoreductase NAD_binding_2 PF03446.15 AIO02710.1 - 0.21 11.7 0.1 0.41 10.8 0.1 1.4 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase OB_NTP_bind PF07717.16 AIO02711.1 - 3e-15 56.3 0.0 6e-15 55.4 0.0 1.5 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.23 AIO02711.1 - 2.1e-13 50.5 0.9 6.8e-13 48.8 0.9 2.0 1 1 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.31 AIO02711.1 - 3.3e-13 50.0 0.0 1.2e-12 48.2 0.0 1.9 2 0 0 2 2 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 AIO02711.1 - 4e-09 36.5 0.0 7.4e-09 35.6 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 AIO02711.1 - 8.8e-05 22.8 0.1 0.00034 20.9 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 AIO02711.1 - 0.006 16.9 1.1 0.019 15.3 0.0 2.3 2 1 0 2 2 2 1 AAA domain T2SSE PF00437.20 AIO02711.1 - 0.0093 15.0 0.1 0.088 11.9 0.0 2.2 2 0 0 2 2 2 1 Type II/IV secretion system protein PhoH PF02562.16 AIO02711.1 - 0.0099 15.3 0.1 0.058 12.9 0.0 2.2 2 0 0 2 2 2 1 PhoH-like protein ResIII PF04851.15 AIO02711.1 - 0.011 15.8 0.0 4 7.4 0.0 2.3 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit ATPase PF06745.13 AIO02711.1 - 0.035 13.4 0.0 0.073 12.4 0.0 1.4 1 0 0 1 1 1 0 KaiC AAA_30 PF13604.6 AIO02711.1 - 0.039 13.7 0.0 0.081 12.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 AIO02711.1 - 0.04 13.4 0.0 0.082 12.4 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region Kringle PF00051.18 AIO02711.1 - 0.041 14.2 0.1 0.082 13.2 0.1 1.4 1 0 0 1 1 1 0 Kringle domain ABC_tran PF00005.27 AIO02711.1 - 0.12 12.9 0.0 0.28 11.7 0.0 1.6 1 0 0 1 1 1 0 ABC transporter AAA_16 PF13191.6 AIO02711.1 - 0.13 12.6 0.1 0.68 10.3 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain Sigma54_activat PF00158.26 AIO02711.1 - 0.15 11.7 0.0 0.35 10.6 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_14 PF13173.6 AIO02711.1 - 0.16 12.0 0.0 7.9 6.5 0.0 2.5 1 1 0 1 1 1 0 AAA domain AAA_29 PF13555.6 AIO02711.1 - 0.19 11.5 0.0 0.45 10.3 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain CUE PF02845.16 AIO02714.1 - 0.0025 17.5 0.0 0.2 11.4 0.0 2.7 2 0 0 2 2 2 2 CUE domain Cullin_binding PF03556.15 AIO02715.1 - 5.1e-20 72.1 1.4 1.2e-19 70.9 1.6 1.5 2 0 0 2 2 2 1 Cullin binding TruD PF01142.18 AIO02719.1 - 4.4e-61 207.0 0.0 2.8e-54 184.5 0.0 2.7 3 0 0 3 3 3 2 tRNA pseudouridine synthase D (TruD) RAB3GAP2_N PF14655.6 AIO02720.1 - 6e-12 45.5 0.0 9.4e-12 44.9 0.0 1.2 1 0 0 1 1 1 1 Rab3 GTPase-activating protein regulatory subunit N-terminus MS_channel PF00924.18 AIO02721.1 - 1.6e-17 63.7 0.6 2e-17 63.4 0.6 1.1 1 0 0 1 1 1 1 Mechanosensitive ion channel Gcd10p PF04189.13 AIO02722.1 - 7.5e-47 159.9 0.2 1.1e-46 159.4 0.2 1.2 1 0 0 1 1 1 1 Gcd10p family LRR_4 PF12799.7 AIO02723.1 - 1.7e-08 34.6 0.5 0.034 14.6 0.1 3.3 2 1 1 3 3 3 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 AIO02723.1 - 4.7e-05 23.1 0.9 0.0039 16.9 0.1 2.9 2 1 2 4 4 4 2 Leucine rich repeat LRR_9 PF14580.6 AIO02723.1 - 7e-05 22.4 0.1 0.0003 20.4 0.1 2.3 1 1 0 1 1 1 1 Leucine-rich repeat FlbT PF07378.11 AIO02724.1 - 0.12 12.4 0.3 2.7 8.1 0.2 2.9 3 0 0 3 3 3 0 Flagellar protein FlbT DUF945 PF06097.11 AIO02725.1 - 0.039 13.1 0.6 0.062 12.4 0.6 1.3 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF945) CBM_21 PF03370.13 AIO02725.1 - 0.16 12.2 0.0 0.46 10.7 0.0 1.8 2 0 0 2 2 2 0 Carbohydrate/starch-binding module (family 21) HMG_box PF00505.19 AIO02727.1 - 0.34 11.4 3.3 0.66 10.4 0.1 3.0 3 1 0 3 3 3 0 HMG (high mobility group) box DUF3106 PF11304.8 AIO02727.1 - 1.2 9.6 10.0 0.88 10.1 0.5 3.3 2 1 0 3 3 3 0 Protein of unknown function (DUF3106) HMG_box_2 PF09011.10 AIO02728.1 - 0.00014 22.3 4.3 0.0073 16.9 0.6 2.5 1 1 1 2 2 2 2 HMG-box domain YABBY PF04690.13 AIO02728.1 - 0.00019 22.0 1.9 0.00023 21.8 1.9 1.1 1 0 0 1 1 1 1 YABBY protein DUF3106 PF11304.8 AIO02728.1 - 0.02 15.4 0.9 0.032 14.7 0.5 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3106) HMG_box PF00505.19 AIO02728.1 - 0.033 14.6 4.5 0.069 13.6 0.2 2.9 2 2 0 2 2 2 0 HMG (high mobility group) box EBP50_C PF09007.11 AIO02729.1 - 1.4 10.0 5.6 1.6 9.8 0.2 2.4 2 0 0 2 2 2 0 EBP50, C-terminal AAA PF00004.29 AIO02730.1 - 1.1e-11 45.3 0.0 5.5e-05 23.6 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 AIO02730.1 - 7.4e-07 29.3 0.0 3e-06 27.3 0.0 2.0 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 AIO02730.1 - 0.00036 21.0 0.7 0.0035 17.7 0.1 2.8 2 1 0 2 2 2 1 AAA ATPase domain DUF815 PF05673.13 AIO02730.1 - 0.0073 15.5 0.0 0.023 13.8 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF815) Gtr1_RagA PF04670.12 AIO02732.1 - 2.7e-67 226.5 0.1 3.5e-67 226.2 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 AIO02732.1 - 7e-07 29.3 0.0 1.5e-06 28.3 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase Arf PF00025.21 AIO02732.1 - 7.2e-06 25.6 0.0 1.4e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 AIO02732.1 - 1.9e-05 24.9 0.0 4.5e-05 23.6 0.0 1.8 2 1 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase YliH PF10799.8 AIO02732.1 - 0.008 16.1 0.6 0.019 14.9 0.0 2.0 2 0 0 2 2 2 1 Biofilm formation protein (YliH/bssR) Ras PF00071.22 AIO02732.1 - 0.011 15.3 0.0 0.017 14.7 0.0 1.3 1 0 0 1 1 1 0 Ras family SRPRB PF09439.10 AIO02732.1 - 0.025 14.0 0.0 0.046 13.1 0.0 1.4 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit Pro-rich_19 PF15455.6 AIO02732.1 - 0.07 12.3 0.0 0.099 11.8 0.0 1.1 1 0 0 1 1 1 0 Proline-rich 19 DUF910 PF06014.11 AIO02732.1 - 0.097 12.7 0.0 0.29 11.2 0.0 1.8 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF910) CDP-OH_P_transf PF01066.21 AIO02734.1 - 9.4e-16 58.3 0.1 9.4e-16 58.3 0.1 3.7 3 1 0 3 3 3 2 CDP-alcohol phosphatidyltransferase Taxilin PF09728.9 AIO02738.1 - 0.0034 16.6 47.6 0.0046 16.2 47.6 1.1 1 0 0 1 1 1 1 Myosin-like coiled-coil protein DUF4200 PF13863.6 AIO02738.1 - 0.012 16.0 6.4 0.012 16.0 6.4 3.6 1 1 3 4 4 4 0 Domain of unknown function (DUF4200) Baculo_F PF12259.8 AIO02738.1 - 1.4 7.3 14.8 0.35 9.3 10.8 1.8 1 1 1 2 2 2 0 Baculovirus F protein KxDL PF10241.9 AIO02738.1 - 9.8 6.5 24.0 0.83 10.0 4.5 3.9 1 1 1 3 3 3 0 Uncharacterized conserved protein LmjF365940-deam PF14421.6 AIO02739.1 - 1.5e-40 138.9 0.1 5.3e-21 75.1 0.0 2.3 1 1 1 2 2 2 2 A distinct subfamily of CDD/CDA-like deaminases DUF5567 PF17722.1 AIO02740.1 - 0.0079 16.1 0.0 5 6.9 0.1 2.3 2 0 0 2 2 2 2 Family of unknown function (DUF5567) DUF4996 PF16387.5 AIO02741.1 - 8.5e-32 109.7 0.2 1.8e-31 108.7 0.1 1.6 2 0 0 2 2 2 1 Domain of unknown function GDPD PF03009.17 AIO02741.1 - 2e-23 83.4 0.2 3.8e-23 82.5 0.1 1.4 1 1 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family PI-PLC-X PF00388.19 AIO02741.1 - 0.0085 15.7 0.2 0.019 14.5 0.2 1.8 1 1 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain FAS_meander PF17951.1 AIO02741.1 - 0.051 13.4 0.0 0.085 12.7 0.0 1.3 1 0 0 1 1 1 0 Fatty acid synthase meander beta sheet domain Tmemb_185A PF10269.9 AIO02742.1 - 1e-06 28.6 13.6 0.0013 18.4 0.4 2.2 2 0 0 2 2 2 2 Transmembrane Fragile-X-F protein RRM_1 PF00076.22 AIO02743.1 - 0.0033 17.2 0.0 0.0077 16.0 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SpoV PF08183.11 AIO02744.1 - 1.5e-12 47.2 0.2 2.4e-12 46.6 0.2 1.3 1 0 0 1 1 1 1 Stage V sporulation protein family AbiH PF14253.6 AIO02745.1 - 0.41 10.5 0.9 1 9.2 0.9 1.6 1 0 0 1 1 1 0 Bacteriophage abortive infection AbiH CCDC144C PF14915.6 AIO02745.1 - 3.4 6.7 39.6 0.035 13.2 4.6 3.4 3 0 0 3 3 3 0 CCDC144C protein coiled-coil region Arabino_trans_N PF17689.1 AIO02746.1 - 0.027 14.6 0.4 0.027 14.6 0.4 2.1 2 0 0 2 2 2 0 Arabinosyltransferase concanavalin like domain Filament PF00038.21 AIO02746.1 - 0.86 9.1 27.4 0.43 10.1 6.4 3.0 1 1 0 2 2 2 0 Intermediate filament protein CorA PF01544.18 AIO02746.1 - 8.4 5.6 13.0 1.3 8.3 8.2 1.9 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein OTU PF02338.19 AIO02747.1 - 0.0018 18.7 0.0 0.0097 16.4 0.0 2.1 2 0 0 2 2 2 1 OTU-like cysteine protease DUF4223 PF13978.6 AIO02747.1 - 0.022 14.7 0.0 0.05 13.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4223) FAP206 PF12018.8 AIO02748.1 - 2.2e-12 47.1 0.1 0.0014 18.2 0.0 4.9 4 0 0 4 4 4 2 Domain of unknown function AAA_17 PF13207.6 AIO02748.1 - 7.1e-05 23.3 0.0 0.79 10.1 0.0 3.7 2 1 0 2 2 2 2 AAA domain AAA_18 PF13238.6 AIO02748.1 - 0.00018 22.1 0.0 0.049 14.2 0.0 3.1 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.6 AIO02748.1 - 0.00053 20.4 7.1 0.002 18.5 0.0 4.7 4 0 0 4 4 4 1 AAA ATPase domain YHS PF04945.13 AIO02748.1 - 0.0022 18.0 6.0 0.076 13.1 0.7 3.6 3 0 0 3 3 3 1 YHS domain AAA_33 PF13671.6 AIO02748.1 - 0.0048 17.1 0.0 0.0048 17.1 0.0 3.8 3 1 1 4 4 3 1 AAA domain HTH_1 PF00126.27 AIO02748.1 - 0.051 13.5 0.0 22 5.1 0.0 3.0 2 0 0 2 2 2 0 Bacterial regulatory helix-turn-helix protein, lysR family TniB PF05621.11 AIO02748.1 - 0.076 12.4 0.0 6.2 6.2 0.0 3.2 3 0 0 3 3 3 0 Bacterial TniB protein AAA PF00004.29 AIO02748.1 - 0.11 12.9 0.0 1.3 9.4 0.0 2.5 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 AIO02748.1 - 0.11 12.4 0.0 0.49 10.4 0.0 2.2 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 AIO02748.1 - 0.15 12.3 0.0 1.4 9.2 0.0 2.7 2 0 0 2 2 2 0 AAA domain Zn_ribbon_2 PF12674.7 AIO02748.1 - 0.21 12.3 1.5 0.84 10.3 1.5 2.1 1 0 0 1 1 1 0 Putative zinc ribbon domain Astro_capsid_p PF12226.8 AIO02748.1 - 2.5 7.2 8.2 9.7 5.2 8.2 2.0 1 0 0 1 1 1 0 Turkey astrovirus capsid protein COG2 PF06148.11 AIO02749.1 - 2.6e-40 137.6 0.0 8.1e-40 136.0 0.0 1.9 1 0 0 1 1 1 1 COG (conserved oligomeric Golgi) complex component, COG2 DUF3510 PF12022.8 AIO02749.1 - 3e-30 105.2 0.5 4.4e-29 101.4 0.1 2.7 1 1 1 2 2 2 1 Domain of unknown function (DUF3510) DARPP-32 PF05395.12 AIO02749.1 - 0.079 13.2 0.0 0.2 11.9 0.0 1.6 1 0 0 1 1 1 0 Protein phosphatase inhibitor 1/DARPP-32 DUF5576 PF17739.1 AIO02749.1 - 0.36 11.0 1.7 3.5 7.8 0.0 2.9 3 0 0 3 3 3 0 Family of unknown function (DUF5576) MIF4G PF02854.19 AIO02751.1 - 1.4e-21 77.1 0.1 2.3e-21 76.4 0.1 1.4 1 0 0 1 1 1 1 MIF4G domain RabGAP-TBC PF00566.18 AIO02752.1 - 1e-58 198.5 0.1 1.4e-58 198.1 0.1 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain RabGAP-TBC PF00566.18 AIO02753.1 - 1.4e-60 204.7 0.2 1.8e-60 204.2 0.2 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain ABC1 PF03109.16 AIO02754.1 - 3.7e-28 98.1 0.0 9.1e-28 96.8 0.0 1.7 1 0 0 1 1 1 1 ABC1 family Pkinase PF00069.25 AIO02754.1 - 4.4e-07 29.5 0.0 0.0019 17.7 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 AIO02754.1 - 4.5e-06 26.1 0.0 0.0078 15.5 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.23 AIO02754.1 - 6.6e-05 22.9 0.0 0.00013 22.0 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 AIO02754.1 - 0.00052 19.7 0.0 0.00097 18.8 0.0 1.4 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.14 AIO02754.1 - 0.095 12.0 0.1 0.15 11.3 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF5616 PF18481.1 AIO02754.1 - 0.1 12.9 0.0 0.21 11.9 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5616) Pkinase_fungal PF17667.1 AIO02754.1 - 0.12 11.1 0.0 0.19 10.5 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase TPR_14 PF13428.6 AIO02755.1 - 0.00066 20.3 6.4 3.1 8.9 0.0 4.9 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_2 PF07719.17 AIO02755.1 - 0.012 15.7 12.2 5.5 7.4 0.3 6.2 7 0 0 7 7 7 0 Tetratricopeptide repeat HrpB1_HrpK PF09613.10 AIO02755.1 - 0.013 15.1 0.3 0.15 11.7 0.1 2.9 3 0 0 3 3 3 0 Bacterial type III secretion protein (HrpB1_HrpK) ANAPC3 PF12895.7 AIO02755.1 - 0.028 14.6 11.0 1.1 9.5 0.6 5.1 5 0 0 5 5 5 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.6 AIO02755.1 - 0.041 14.4 10.5 5 7.7 0.7 4.9 5 1 0 6 6 6 0 Tetratricopeptide repeat PPR PF01535.20 AIO02755.1 - 0.11 12.7 0.0 22 5.6 0.0 3.7 4 0 0 4 4 4 0 PPR repeat TPR_16 PF13432.6 AIO02755.1 - 0.26 12.0 15.0 4 8.2 0.2 5.3 5 1 0 6 6 6 0 Tetratricopeptide repeat TPR_6 PF13174.6 AIO02755.1 - 0.67 10.7 10.4 0.93 10.3 0.2 5.1 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_4 PF07721.14 AIO02755.1 - 0.69 10.7 9.8 23 6.0 0.6 5.2 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_12 PF13424.6 AIO02755.1 - 1.1 9.6 15.7 0.67 10.3 0.8 4.5 5 1 0 5 5 5 0 Tetratricopeptide repeat EF-hand_7 PF13499.6 AIO02756.1 - 3.6e-15 56.2 1.8 5.5e-07 30.0 0.0 2.4 1 1 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 AIO02756.1 - 1.9e-09 36.4 1.6 0.001 18.4 0.0 4.6 4 1 0 4 4 4 2 EF hand EF-hand_6 PF13405.6 AIO02756.1 - 2.4e-09 36.4 2.6 0.00013 21.6 0.0 4.2 4 1 0 4 4 4 2 EF-hand domain EF-hand_8 PF13833.6 AIO02756.1 - 3.7e-08 33.1 0.6 0.016 15.1 0.3 3.4 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_9 PF14658.6 AIO02756.1 - 3.3e-05 24.1 0.1 0.0032 17.8 0.0 2.2 2 0 0 2 2 2 1 EF-hand domain EF-hand_5 PF13202.6 AIO02756.1 - 0.003 17.0 0.1 5.7 6.6 0.0 3.3 3 0 0 3 3 3 2 EF hand PheRS_DBD2 PF18554.1 AIO02756.1 - 0.22 11.6 1.8 3.9 7.6 0.1 3.0 3 0 0 3 3 3 0 PheRS DNA binding domain 2 ATP_bind_3 PF01171.20 AIO02757.1 - 2.9e-16 59.8 0.0 5.2e-16 58.9 0.0 1.4 1 1 0 1 1 1 1 PP-loop family zn-ribbon_14 PF16503.5 AIO02757.1 - 2.7e-12 46.0 2.7 2.7e-12 46.0 2.7 4.5 5 0 0 5 5 5 1 Zinc-ribbon tRNA_Me_trans PF03054.16 AIO02757.1 - 0.014 14.3 0.0 0.028 13.2 0.0 1.5 1 1 0 1 1 1 0 tRNA methyl transferase PAPS_reduct PF01507.19 AIO02757.1 - 0.026 14.6 0.0 0.04 13.9 0.0 1.3 1 0 0 1 1 1 0 Phosphoadenosine phosphosulfate reductase family TF_Zn_Ribbon PF08271.12 AIO02757.1 - 0.073 12.6 2.0 0.22 11.0 0.1 2.5 2 0 0 2 2 2 0 TFIIB zinc-binding Rab5-bind PF09311.11 AIO02758.1 - 0.0017 17.8 0.7 0.0029 17.1 0.7 1.2 1 0 0 1 1 1 1 Rabaptin-like protein zf_C2H2_6 PF18450.1 AIO02758.1 - 0.097 12.4 0.4 0.24 11.1 0.4 1.6 1 0 0 1 1 1 0 Zinc Finger domain zf_C2HC_14 PF18574.1 AIO02758.1 - 0.24 11.2 0.7 0.55 10.1 0.7 1.6 1 0 0 1 1 1 0 C2HC Zing finger domain Fis1_TPR_C PF14853.6 AIO02760.1 - 4e-05 23.6 1.7 0.00013 22.0 1.1 2.0 2 0 0 2 2 2 1 Fis1 C-terminal tetratricopeptide repeat TPR_1 PF00515.28 AIO02760.1 - 0.026 14.3 0.1 0.052 13.4 0.1 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_2 PF07719.17 AIO02760.1 - 0.074 13.2 0.2 0.22 11.7 0.1 1.9 2 0 0 2 2 2 0 Tetratricopeptide repeat Kelch_5 PF13854.6 AIO02762.1 - 2.5e-14 52.9 2.1 0.00049 20.0 0.0 5.3 6 0 0 6 6 6 3 Kelch motif Kelch_1 PF01344.25 AIO02762.1 - 9.3e-12 44.3 1.3 6.2e-05 22.5 0.1 5.0 5 0 0 5 5 5 2 Kelch motif Kelch_4 PF13418.6 AIO02762.1 - 5.6e-10 39.1 12.6 0.0057 16.6 0.2 5.6 6 0 0 6 6 6 4 Galactose oxidase, central domain Kelch_6 PF13964.6 AIO02762.1 - 3.4e-07 30.3 1.2 2.2 8.7 0.0 5.1 4 1 1 5 5 5 3 Kelch motif Kelch_2 PF07646.15 AIO02762.1 - 1.2e-05 25.1 1.1 1.3 9.1 0.0 5.2 5 0 0 5 5 5 2 Kelch motif Kelch_3 PF13415.6 AIO02762.1 - 0.018 15.3 17.5 0.33 11.3 0.0 6.4 7 1 0 7 7 7 0 Galactose oxidase, central domain Suc_Fer-like PF06999.12 AIO02763.1 - 4.5e-27 95.2 0.1 6.3e-27 94.7 0.1 1.2 1 0 0 1 1 1 1 Sucrase/ferredoxin-like PB1 PF00564.24 AIO02763.1 - 0.0099 15.8 0.0 0.019 14.9 0.0 1.4 1 0 0 1 1 1 1 PB1 domain Vps54 PF07928.12 AIO02766.1 - 1.8e-22 80.3 0.1 6.7e-21 75.1 0.0 3.2 2 1 0 2 2 2 1 Vps54-like protein GCN5L1 PF06320.13 AIO02766.1 - 0.0034 17.5 0.0 0.01 16.0 0.0 1.8 1 0 0 1 1 1 1 GCN5-like protein 1 (GCN5L1) Tropomyosin_1 PF12718.7 AIO02767.1 - 6.8e-06 26.3 2.2 6.8e-06 26.3 2.2 3.1 4 0 0 4 4 4 1 Tropomyosin like CBFB_NFYA PF02045.15 AIO02767.1 - 0.27 11.9 2.4 0.91 10.2 2.4 2.0 1 0 0 1 1 1 0 CCAAT-binding transcription factor (CBF-B/NF-YA) subunit B AAA_13 PF13166.6 AIO02767.1 - 2.9 6.4 13.7 5.7 5.4 13.7 1.4 1 0 0 1 1 1 0 AAA domain Arf PF00025.21 AIO02768.1 - 5e-60 201.9 0.0 5.6e-60 201.8 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 AIO02768.1 - 8.7e-13 48.5 0.0 1.2e-12 48.1 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 AIO02768.1 - 6.2e-12 45.4 0.0 7.4e-12 45.2 0.0 1.1 1 0 0 1 1 1 1 Ras family G-alpha PF00503.20 AIO02768.1 - 1.8e-11 43.8 0.0 1.1e-08 34.6 0.0 2.5 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.12 AIO02768.1 - 1.6e-10 40.8 0.0 1.9e-10 40.5 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 AIO02768.1 - 1.7e-09 37.7 0.0 2.6e-09 37.1 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 AIO02768.1 - 2.4e-09 36.9 0.0 2.8e-09 36.7 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit FeoB_N PF02421.18 AIO02768.1 - 0.0056 16.2 0.1 0.12 11.9 0.1 2.4 1 1 0 1 1 1 1 Ferrous iron transport protein B GTP_EFTU PF00009.27 AIO02768.1 - 0.011 15.2 0.0 0.029 13.9 0.0 1.6 1 1 0 2 2 2 0 Elongation factor Tu GTP binding domain Dynamin_N PF00350.23 AIO02768.1 - 0.04 14.0 0.0 5.8 6.9 0.0 2.1 2 0 0 2 2 2 0 Dynamin family TniB PF05621.11 AIO02768.1 - 0.068 12.6 0.0 0.12 11.7 0.0 1.4 1 0 0 1 1 1 0 Bacterial TniB protein AAA_28 PF13521.6 AIO02769.1 - 0.0081 16.4 0.0 0.021 15.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain Ras PF00071.22 AIO02770.1 - 2.3e-45 154.1 0.2 3.1e-45 153.7 0.2 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.13 AIO02770.1 - 3.8e-30 104.6 0.2 7.8e-30 103.6 0.0 1.6 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 AIO02770.1 - 2.6e-07 30.3 0.0 3.6e-07 29.8 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 AIO02770.1 - 0.0005 20.1 0.0 0.0013 18.8 0.0 1.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 AIO02770.1 - 0.0075 15.8 0.1 1.7 8.2 0.0 2.4 2 0 0 2 2 2 2 Ferrous iron transport protein B RsgA_GTPase PF03193.16 AIO02770.1 - 0.024 14.5 0.1 1.3 8.9 0.0 2.4 2 1 0 2 2 2 0 RsgA GTPase TniB PF05621.11 AIO02770.1 - 0.028 13.8 0.0 0.11 11.9 0.0 1.9 2 0 0 2 2 2 0 Bacterial TniB protein Gtr1_RagA PF04670.12 AIO02770.1 - 0.044 13.1 0.2 0.14 11.4 0.0 1.8 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region PduV-EutP PF10662.9 AIO02770.1 - 0.056 13.2 0.0 1.3 8.7 0.0 2.2 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation DLIC PF05783.11 AIO02770.1 - 0.1 11.4 4.6 0.28 10.0 0.0 2.0 2 0 0 2 2 2 0 Dynein light intermediate chain (DLIC) DnaJ_C PF01556.18 AIO02771.1 - 7.2e-37 126.7 0.0 1e-36 126.3 0.0 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 AIO02771.1 - 7.9e-27 93.2 6.9 1.4e-26 92.4 6.9 1.4 1 0 0 1 1 1 1 DnaJ domain Sugar_tr PF00083.24 AIO02772.1 - 1.1e-98 331.1 39.4 3.3e-60 204.2 17.8 2.1 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 AIO02772.1 - 1.8e-18 66.6 31.5 1.7e-15 56.8 33.6 2.3 2 1 0 2 2 2 2 Major Facilitator Superfamily YqhR PF11085.8 AIO02772.1 - 0.0094 15.9 2.1 0.0094 15.9 2.1 2.9 3 0 0 3 3 3 1 Conserved membrane protein YqhR S-methyl_trans PF02574.16 AIO02773.1 - 5.2e-71 239.6 0.1 6e-71 239.4 0.1 1.0 1 0 0 1 1 1 1 Homocysteine S-methyltransferase Kelch_1 PF01344.25 AIO02773.1 - 0.0025 17.4 0.1 0.019 14.5 0.0 2.2 2 0 0 2 2 2 1 Kelch motif FliG_M PF14841.6 AIO02773.1 - 0.051 13.8 0.2 9 6.6 0.1 2.7 2 0 0 2 2 2 0 FliG middle domain PI3_PI4_kinase PF00454.27 AIO02774.1 - 4e-63 213.6 0.0 7.1e-63 212.7 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FAT PF02259.23 AIO02774.1 - 2e-53 181.9 0.4 9.4e-53 179.6 0.2 2.2 2 0 0 2 2 2 1 FAT domain DUF3385 PF11865.8 AIO02774.1 - 9.6e-22 77.6 0.7 2.1e-19 70.0 0.0 4.4 5 0 0 5 5 5 1 Domain of unknown function (DUF3385) FRB_dom PF08771.11 AIO02774.1 - 8.7e-21 74.2 0.1 3.8e-20 72.1 0.1 2.3 1 0 0 1 1 1 1 FKBP12-rapamycin binding domain FATC PF02260.20 AIO02774.1 - 3e-15 55.7 0.2 7.7e-15 54.4 0.2 1.8 1 0 0 1 1 1 1 FATC domain HEAT_2 PF13646.6 AIO02774.1 - 0.001 19.4 7.4 3 8.3 0.1 6.0 7 0 0 7 7 7 1 HEAT repeats HEAT PF02985.22 AIO02774.1 - 1.1 9.8 6.6 27 5.4 0.1 6.2 6 0 0 6 6 6 0 HEAT repeat FANCI_S2 PF14676.6 AIO02774.1 - 3.6 7.9 7.4 66 3.8 0.1 5.1 4 1 1 5 5 5 0 FANCI solenoid 2 PEX11 PF05648.14 AIO02775.1 - 0.013 14.9 0.3 0.023 14.1 0.3 1.6 1 1 0 1 1 1 0 Peroxisomal biogenesis factor 11 (PEX11) UTP15_C PF09384.10 AIO02775.1 - 0.029 14.1 0.2 0.11 12.2 0.0 1.9 2 0 0 2 2 2 0 UTP15 C terminal Flexi_CP PF00286.20 AIO02775.1 - 0.073 13.0 0.2 1.9 8.4 0.0 2.1 2 0 0 2 2 2 0 Viral coat protein HECT PF00632.25 AIO02776.1 - 2e-53 181.9 0.0 5.2e-53 180.5 0.0 1.7 2 0 0 2 2 2 1 HECT-domain (ubiquitin-transferase) SPRY PF00622.28 AIO02776.1 - 2.6e-41 140.5 0.1 9.8e-16 58.0 0.0 4.1 4 0 0 4 4 4 3 SPRY domain Laminin_G_3 PF13385.6 AIO02776.1 - 1.9e-16 60.6 0.0 2.1e-07 31.2 0.0 3.4 4 0 0 4 4 4 2 Concanavalin A-like lectin/glucanases superfamily Pox_MCEL PF03291.16 AIO02777.1 - 0.081 12.0 0.0 0.12 11.5 0.0 1.2 1 0 0 1 1 1 0 mRNA capping enzyme PH_11 PF15413.6 AIO02778.1 - 0.004 17.5 0.0 0.0077 16.6 0.0 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain CAF1 PF04857.20 AIO02780.1 - 1.1e-67 228.5 0.2 1.5e-67 228.1 0.2 1.2 1 0 0 1 1 1 1 CAF1 family ribonuclease Stap_Strp_toxin PF01123.20 AIO02780.1 - 0.15 12.9 0.3 4.1 8.3 0.1 2.6 2 0 0 2 2 2 0 Staphylococcal/Streptococcal toxin, OB-fold domain Tma16 PF11176.8 AIO02781.1 - 2.4e-23 82.6 0.1 2.4e-23 82.6 0.1 1.8 2 0 0 2 2 2 1 Translation machinery-associated protein 16 RabGAP-TBC PF00566.18 AIO02782.1 - 8.1e-13 48.5 0.5 1.2e-12 47.9 0.5 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain ArfGap PF01412.18 AIO02782.1 - 0.036 14.1 0.8 0.3 11.2 0.1 2.3 2 0 0 2 2 2 0 Putative GTPase activating protein for Arf Nucleoporin_FG PF13634.6 AIO02782.1 - 6.9 7.6 34.1 8.5 7.3 18.4 2.6 1 1 1 2 2 2 0 Nucleoporin FG repeat region DUF1126 PF06565.12 AIO02783.1 - 1.2e-62 208.2 0.1 8.2e-23 80.2 0.0 3.5 3 0 0 3 3 3 3 DUF1126 PH-like domain EF-hand_7 PF13499.6 AIO02783.1 - 8.4e-06 26.2 0.1 0.00088 19.7 0.0 3.4 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_8 PF13833.6 AIO02783.1 - 0.0002 21.2 0.3 0.42 10.5 0.0 3.0 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_6 PF13405.6 AIO02783.1 - 0.069 13.1 0.3 37 4.6 0.0 3.9 4 0 0 4 4 4 0 EF-hand domain MTHFR PF02219.17 AIO02784.1 - 1.1e-93 313.8 0.0 1.3e-93 313.5 0.0 1.0 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase Ribosomal_S8e PF01201.22 AIO02785.1 - 7.3e-45 152.5 3.3 7.3e-45 152.5 3.3 1.5 1 1 0 1 1 1 1 Ribosomal protein S8e DUF3746 PF12562.8 AIO02785.1 - 0.085 12.8 0.5 0.41 10.6 0.2 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF3746) Ribosomal_L26 PF16906.5 AIO02785.1 - 0.15 12.5 6.8 2.9 8.4 3.0 2.4 2 0 0 2 2 2 0 Ribosomal proteins L26 eukaryotic, L24P archaeal CCDC-167 PF15188.6 AIO02785.1 - 0.16 12.4 2.8 0.33 11.3 2.8 1.6 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 167 Peptidase_S46 PF10459.9 AIO02785.1 - 0.42 9.2 8.0 0.5 8.9 8.0 1.1 1 0 0 1 1 1 0 Peptidase S46 HU-CCDC81_euk_2 PF18289.1 AIO02786.1 - 1.4e-09 37.9 0.0 2.4e-09 37.2 0.0 1.3 1 0 0 1 1 1 1 CCDC81 eukaryotic HU domain 2 TB2_DP1_HVA22 PF03134.19 AIO02787.1 - 0.085 12.8 2.2 0.12 12.3 2.0 1.5 1 1 0 1 1 1 0 TB2/DP1, HVA22 family Sec23_trunk PF04811.15 AIO02788.1 - 1.8e-50 171.8 0.0 3.4e-50 170.9 0.0 1.4 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.15 AIO02788.1 - 5.2e-23 80.8 0.1 2.9e-22 78.4 0.1 2.2 2 0 0 2 2 2 1 Sec23/Sec24 helical domain Sec23_BS PF08033.12 AIO02788.1 - 6.8e-21 74.8 1.1 1.9e-20 73.4 1.1 1.8 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.15 AIO02788.1 - 3e-11 43.2 0.7 3e-11 43.2 0.7 2.6 3 0 0 3 3 3 1 Sec23/Sec24 zinc finger Gelsolin PF00626.22 AIO02788.1 - 2.4e-06 27.3 0.0 7.3e-06 25.8 0.0 1.8 1 0 0 1 1 1 1 Gelsolin repeat ComP_DUS PF16732.5 AIO02789.1 - 0.062 14.2 0.2 0.31 12.0 0.0 2.2 2 1 1 3 3 3 0 Type IV minor pilin ComP, DNA uptake sequence receptor DUF1539 PF07560.11 AIO02789.1 - 0.19 11.8 0.7 6.7 6.8 0.1 2.2 1 1 0 2 2 2 0 Domain of Unknown Function (DUF1539) Pkinase PF00069.25 AIO02792.1 - 7.7e-61 205.8 0.0 9.4e-61 205.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 AIO02792.1 - 4.8e-25 88.3 0.0 6.4e-25 87.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 AIO02792.1 - 4.5e-09 36.0 0.0 7.5e-09 35.3 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 AIO02792.1 - 9.2e-05 21.9 0.6 0.00016 21.1 0.6 1.4 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 AIO02792.1 - 0.054 13.4 0.5 2.1 8.2 0.1 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family His_Phos_2 PF00328.22 AIO02793.1 - 1.5e-14 54.1 1.8 2.3e-08 33.8 0.0 3.1 1 1 1 3 3 3 2 Histidine phosphatase superfamily (branch 2) SR-25 PF10500.9 AIO02793.1 - 6.4 6.3 8.9 10 5.7 8.9 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein UFD1 PF03152.14 AIO02794.1 - 4.6e-47 159.7 0.0 6.1e-47 159.3 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin fusion degradation protein UFD1 NCE101 PF11654.8 AIO02795.1 - 0.12 12.1 0.2 0.52 10.1 0.1 2.1 2 0 0 2 2 2 0 Non-classical export protein 1 PCI PF01399.27 AIO02796.1 - 0.05 14.1 0.0 0.099 13.2 0.0 1.5 1 0 0 1 1 1 0 PCI domain DUF3551 PF12071.8 AIO02798.1 - 0.039 14.0 0.2 0.074 13.1 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3551) Phage_holin_3_6 PF07332.11 AIO02798.1 - 0.12 12.4 2.7 0.17 11.9 1.5 1.7 2 0 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III SLC3A2_N PF16028.5 AIO02798.1 - 0.28 10.8 7.1 4.8 6.8 0.9 2.5 1 1 1 2 2 2 0 Solute carrier family 3 member 2 N-terminus 2TM PF13239.6 AIO02798.1 - 1 9.7 9.3 0.2 12.0 5.7 1.7 1 1 1 2 2 2 0 2TM domain SdpI PF13630.6 AIO02798.1 - 1.7 8.8 8.0 0.51 10.5 4.8 1.7 1 1 1 2 2 2 0 SdpI/YhfL protein family COX7a PF02238.15 AIO02798.1 - 6.8 7.2 8.8 0.25 11.7 0.7 2.6 2 1 1 3 3 3 0 Cytochrome c oxidase subunit VII Myb_DNA-bind_7 PF15963.5 AIO02800.1 - 7.3e-25 86.7 0.7 1.4e-24 85.8 0.7 1.4 1 0 0 1 1 1 1 Myb DNA-binding like Myb_DNA-binding PF00249.31 AIO02800.1 - 3.1e-06 27.3 0.0 6e-06 26.4 0.0 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 AIO02800.1 - 0.031 14.5 0.0 0.065 13.5 0.0 1.5 1 0 0 1 1 1 0 Myb-like DNA-binding domain DLH PF01738.18 AIO02801.1 - 3.1e-25 89.0 0.1 3.6e-25 88.8 0.1 1.0 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_1 PF00561.20 AIO02801.1 - 0.0029 17.3 0.0 0.0057 16.3 0.0 1.5 1 1 1 2 2 2 1 alpha/beta hydrolase fold BAAT_C PF08840.11 AIO02801.1 - 0.0051 16.8 0.0 0.0073 16.2 0.0 1.2 1 0 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal DUF3530 PF12048.8 AIO02801.1 - 0.0086 15.5 0.0 0.011 15.2 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3530) DUF1847 PF08901.11 AIO02801.1 - 0.071 12.8 0.0 0.39 10.4 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1847) YdfZ PF14001.6 AIO02801.1 - 0.15 12.5 0.0 0.28 11.6 0.0 1.4 1 0 0 1 1 1 0 YdfZ protein PCMT PF01135.19 AIO02802.1 - 1.7e-47 161.9 0.0 2.4e-47 161.4 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_24 PF13578.6 AIO02802.1 - 0.00057 20.9 0.0 0.00094 20.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain DUF4491 PF14898.6 AIO02802.1 - 0.0013 19.1 0.1 1.1 9.8 0.0 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF4491) Methyltransf_32 PF13679.6 AIO02802.1 - 0.0035 17.3 0.0 0.0049 16.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 AIO02802.1 - 0.01 16.5 0.0 0.02 15.6 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.6 AIO02802.1 - 0.047 13.5 0.0 0.066 13.0 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.12 AIO02802.1 - 0.081 13.6 0.0 0.18 12.5 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_23 PF13489.6 AIO02802.1 - 0.12 12.2 0.0 0.15 11.8 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain ACBP PF00887.19 AIO02803.1 - 1.1e-14 54.4 0.1 2e-14 53.5 0.1 1.5 1 0 0 1 1 1 1 Acyl CoA binding protein Peptidase_S8 PF00082.22 AIO02804.1 - 0.029 13.6 4.6 0.04 13.2 4.6 1.1 1 0 0 1 1 1 0 Subtilase family NYD-SP28_assoc PF14775.6 AIO02806.1 - 2e-20 72.7 2.3 2e-20 72.7 2.3 4.2 5 1 1 6 6 6 1 Sperm tail C-terminal domain NYD-SP28 PF14772.6 AIO02806.1 - 6.2e-18 64.7 8.9 6.2e-18 64.7 8.9 5.1 5 0 0 5 5 5 2 Sperm tail RPW8 PF05659.11 AIO02806.1 - 0.56 9.9 7.1 0.065 12.9 0.4 2.6 2 1 0 2 2 2 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 DUF948 PF06103.11 AIO02806.1 - 2.8 8.3 9.7 1.4 9.3 1.6 3.7 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) Glyco_trans_1_2 PF13524.6 AIO02806.1 - 5.4 7.5 9.1 0.97 9.9 1.0 3.4 2 0 0 2 2 2 0 Glycosyl transferases group 1 Mito_carr PF00153.27 AIO02808.1 - 1.2e-31 108.5 4.8 4.6e-12 45.7 0.0 3.1 2 1 1 3 3 3 3 Mitochondrial carrier protein SAS-6_N PF16531.5 AIO02811.1 - 5.4e-23 81.4 0.2 8e-23 80.8 0.2 1.3 1 0 0 1 1 1 1 Centriolar protein SAS N-terminal CSD PF00313.22 AIO02811.1 - 0.081 12.8 0.0 0.29 11.0 0.0 1.9 2 0 0 2 2 2 0 'Cold-shock' DNA-binding domain Metalloenzyme PF01676.18 AIO02812.1 - 1.8e-81 273.2 0.0 2.1e-81 273.0 0.0 1.0 1 0 0 1 1 1 1 Metalloenzyme superfamily iPGM_N PF06415.13 AIO02812.1 - 3.6e-60 203.1 0.1 5.3e-60 202.5 0.1 1.2 1 0 0 1 1 1 1 BPG-independent PGAM N-terminus (iPGM_N) Phosphodiest PF01663.22 AIO02812.1 - 0.00041 20.1 0.0 0.00082 19.0 0.0 1.4 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase PglZ PF08665.12 AIO02812.1 - 0.0064 16.6 0.1 0.012 15.8 0.1 1.3 1 0 0 1 1 1 1 PglZ domain PGM_PMM_II PF02879.16 AIO02812.1 - 0.086 13.5 1.5 5.3 7.7 0.0 3.8 5 0 0 5 5 5 0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II FtsJ PF01728.19 AIO02813.1 - 2.2e-26 93.0 0.0 1.9e-25 90.0 0.0 2.0 2 0 0 2 2 2 1 FtsJ-like methyltransferase Cyt-b5 PF00173.28 AIO02814.1 - 4.6e-12 45.9 0.0 5.8e-12 45.6 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Spc7 PF08317.11 AIO02815.1 - 0.0049 15.8 6.4 0.0049 15.8 6.4 2.0 1 1 1 2 2 2 1 Spc7 kinetochore protein Val_tRNA-synt_C PF10458.9 AIO02815.1 - 0.0063 16.8 0.3 0.0063 16.8 0.3 3.6 3 0 0 3 3 3 1 Valyl tRNA synthetase tRNA binding arm GrpE PF01025.19 AIO02815.1 - 0.049 13.3 0.9 0.049 13.3 0.9 2.7 1 1 1 2 2 2 0 GrpE DUF812 PF05667.11 AIO02815.1 - 0.11 11.4 14.4 0.15 10.9 14.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF812) KIAA1430 PF13879.6 AIO02815.1 - 0.26 12.1 4.5 0.18 12.6 2.5 1.7 1 1 1 2 2 2 0 KIAA1430 homologue UPF0242 PF06785.11 AIO02815.1 - 0.61 10.2 15.8 1.3 9.1 15.7 1.5 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus ACCA PF03255.14 AIO02815.1 - 0.75 9.7 9.0 21 4.9 8.3 2.6 1 1 1 2 2 2 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit Exonuc_VII_L PF02601.15 AIO02815.1 - 2.7 7.5 10.6 3.4 7.2 10.6 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit CENP-H PF05837.12 AIO02815.1 - 4.2 7.8 18.8 12 6.3 3.1 2.1 1 1 1 2 2 2 0 Centromere protein H (CENP-H) FAM76 PF16046.5 AIO02815.1 - 6.6 6.0 11.9 4.7 6.5 8.7 2.0 1 1 1 2 2 2 0 FAM76 protein HABP4_PAI-RBP1 PF04774.15 AIO02815.1 - 8 7.3 11.9 11 6.9 11.9 1.4 1 1 0 1 1 1 0 Hyaluronan / mRNA binding family YlqD PF11068.8 AIO02815.1 - 9 6.7 12.8 6.2 7.2 9.0 2.0 1 1 0 2 2 2 0 YlqD protein Solute_trans_a PF03619.16 AIO02816.1 - 1e-77 261.3 15.1 1.7e-77 260.6 15.1 1.3 1 0 0 1 1 1 1 Organic solute transporter Ostalpha WBS28 PF15164.6 AIO02816.1 - 0.03 13.6 1.6 0.7 9.1 0.3 2.8 2 1 0 2 2 2 0 Williams-Beuren syndrome chromosomal region 28 protein homologue NUFIP1 PF10453.9 AIO02816.1 - 0.28 11.1 0.5 0.45 10.4 0.5 1.3 1 0 0 1 1 1 0 Nuclear fragile X mental retardation-interacting protein 1 (NUFIP1) DUF4179 PF13786.6 AIO02816.1 - 0.9 10.1 4.1 59 4.2 4.1 2.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4179) DUF3382 PF11862.8 AIO02816.1 - 1.7 8.9 5.3 11 6.4 0.5 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3382) DUF3671 PF12420.8 AIO02816.1 - 7.6 6.7 11.5 6.2 6.9 0.1 3.1 3 0 0 3 3 3 0 Protein of unknown function AAA_22 PF13401.6 AIO02817.1 - 1.1e-05 25.7 0.0 3.3e-05 24.2 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 AIO02817.1 - 0.0011 19.4 0.4 0.0028 18.1 0.4 2.0 1 1 0 1 1 1 1 AAA ATPase domain AAA_25 PF13481.6 AIO02817.1 - 0.064 12.8 0.1 0.97 9.0 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 AIO02817.1 - 0.099 12.9 0.0 0.22 11.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain RNA12 PF10443.9 AIO02817.1 - 0.17 10.6 0.0 0.27 9.9 0.0 1.2 1 0 0 1 1 1 0 RNA12 protein DNA_pol3_delta2 PF13177.6 AIO02818.1 - 1.1e-13 51.2 0.0 1.9e-13 50.6 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA PF00004.29 AIO02818.1 - 6.7e-07 29.8 0.0 2.4e-06 28.0 0.0 1.9 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Rep_fac_C PF08542.11 AIO02818.1 - 0.00014 22.2 0.0 0.00031 21.1 0.0 1.6 1 0 0 1 1 1 1 Replication factor C C-terminal domain Rad17 PF03215.15 AIO02818.1 - 0.0006 19.8 0.0 0.0016 18.4 0.0 1.7 2 0 0 2 2 2 1 Rad17 P-loop domain AAA_24 PF13479.6 AIO02818.1 - 0.00085 19.1 0.0 0.0017 18.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.14 AIO02818.1 - 0.001 19.1 0.0 0.0064 16.5 0.0 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 AIO02818.1 - 0.004 16.6 0.0 0.12 11.7 0.0 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_16 PF13191.6 AIO02818.1 - 0.0042 17.5 0.0 0.1 13.0 0.0 2.5 2 1 0 2 2 2 1 AAA ATPase domain RuvB_N PF05496.12 AIO02818.1 - 0.011 15.5 0.0 0.23 11.2 0.0 2.4 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain Sigma54_activ_2 PF14532.6 AIO02818.1 - 0.028 14.5 0.0 1.1 9.4 0.0 2.3 2 0 0 2 2 2 0 Sigma-54 interaction domain Sigma54_activat PF00158.26 AIO02818.1 - 0.032 13.9 0.0 3.7 7.2 0.0 2.9 3 0 0 3 3 3 0 Sigma-54 interaction domain AAA_22 PF13401.6 AIO02818.1 - 0.079 13.2 0.0 0.49 10.7 0.0 2.3 2 1 0 2 2 2 0 AAA domain Peptidase_S9_N PF02897.15 AIO02821.1 - 3.5e-94 316.0 4.5 4.6e-94 315.6 4.5 1.1 1 0 0 1 1 1 1 Prolyl oligopeptidase, N-terminal beta-propeller domain Peptidase_S9 PF00326.21 AIO02821.1 - 1.1e-61 208.0 0.1 2.3e-61 207.0 0.0 1.6 2 0 0 2 2 2 1 Prolyl oligopeptidase family Esterase PF00756.20 AIO02821.1 - 0.00085 19.0 0.0 0.0017 18.0 0.0 1.5 1 0 0 1 1 1 1 Putative esterase Hydrolase_4 PF12146.8 AIO02821.1 - 0.038 13.3 0.0 0.074 12.3 0.0 1.4 1 0 0 1 1 1 0 Serine aminopeptidase, S33 OSCP PF00213.18 AIO02822.1 - 1.2e-07 32.0 1.2 4.6e-07 30.1 1.2 1.9 1 1 0 1 1 1 1 ATP synthase delta (OSCP) subunit Adaptin_N PF01602.20 AIO02823.1 - 8.5e-100 334.8 2.8 1e-99 334.5 2.8 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 AIO02823.1 - 6.2e-48 162.9 0.8 4.5e-47 160.1 0.0 2.6 3 0 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 AIO02823.1 - 7.1e-11 42.3 3.0 3.6e-05 24.1 0.0 5.1 4 1 1 5 5 5 2 HEAT repeats HEAT PF02985.22 AIO02823.1 - 1.6e-06 27.9 8.0 0.046 14.0 0.0 5.6 6 0 0 6 6 6 2 HEAT repeat RTP1_C1 PF10363.9 AIO02823.1 - 0.003 17.7 0.2 0.81 9.9 0.0 3.4 3 0 0 3 3 3 1 Required for nuclear transport of RNA pol II C-terminus 1 RIX1 PF08167.12 AIO02823.1 - 0.0066 16.2 2.3 0.61 9.8 0.1 3.7 3 1 1 4 4 4 1 rRNA processing/ribosome biogenesis CAP18_C PF12153.8 AIO02823.1 - 0.13 12.2 0.4 0.37 10.7 0.4 1.8 1 0 0 1 1 1 0 LPS binding domain of CAP18 (C terminal) VHS PF00790.19 AIO02823.1 - 0.14 12.0 1.0 0.37 10.6 0.1 2.1 2 0 0 2 2 2 0 VHS domain HEAT_EZ PF13513.6 AIO02823.1 - 0.17 12.4 3.3 11 6.7 0.1 4.4 4 1 1 5 5 5 0 HEAT-like repeat NIF PF03031.18 AIO02824.1 - 1.7e-31 109.1 0.0 2.5e-31 108.6 0.0 1.3 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase SET PF00856.28 AIO02825.1 - 6.4e-16 59.2 0.0 5.5e-15 56.2 0.0 2.1 1 1 0 1 1 1 1 SET domain SAF PF08666.12 AIO02825.1 - 0.051 14.2 0.0 3.4 8.4 0.0 2.4 2 0 0 2 2 2 0 SAF domain AFG1_ATPase PF03969.16 AIO02826.1 - 8.6e-54 182.8 2.6 4.5e-53 180.4 0.1 2.4 3 0 0 3 3 3 1 AFG1-like ATPase AAA_16 PF13191.6 AIO02826.1 - 1.5e-05 25.5 0.4 0.00021 21.7 0.2 2.5 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 AIO02826.1 - 0.009 16.3 0.1 0.11 12.7 0.0 2.6 2 1 0 2 2 2 1 AAA domain AAA_19 PF13245.6 AIO02826.1 - 0.05 13.9 0.1 4.5 7.6 0.1 2.9 2 1 0 2 2 2 0 AAA domain E3_UFM1_ligase PF09743.9 AIO02827.1 - 2.5e-74 250.3 0.0 5.6e-74 249.2 0.0 1.6 1 0 0 1 1 1 1 E3 UFM1-protein ligase 1 Swm2 PF17083.5 AIO02827.1 - 0.16 12.0 1.3 0.44 10.6 0.1 2.2 2 0 0 2 2 2 0 Nucleolar protein Swm2 4HBT PF03061.22 AIO02828.1 - 0.00015 22.1 0.0 0.00024 21.4 0.0 1.3 1 0 0 1 1 1 1 Thioesterase superfamily DUF4442 PF14539.6 AIO02828.1 - 0.0033 17.5 0.0 0.0047 17.1 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4442) SET PF00856.28 AIO02829.1 - 1e-05 26.0 0.0 0.00049 20.5 0.0 2.3 1 1 0 1 1 1 1 SET domain TMEM65 PF10507.9 AIO02830.1 - 8.7e-38 128.6 2.3 1.5e-37 127.8 2.3 1.4 1 0 0 1 1 1 1 Transmembrane protein 65 EF-hand_1 PF00036.32 AIO02830.1 - 1.4e-07 30.5 0.1 0.0015 18.0 0.0 3.1 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.6 AIO02830.1 - 6.1e-05 22.6 0.1 0.013 15.4 0.0 3.1 3 0 0 3 3 3 1 EF-hand domain EF-hand_7 PF13499.6 AIO02830.1 - 7.9e-05 23.0 0.9 0.17 12.3 0.1 3.3 3 1 1 4 4 4 3 EF-hand domain pair EF-hand_14 PF17959.1 AIO02830.1 - 0.0026 18.1 0.3 0.012 15.9 0.1 2.1 2 0 0 2 2 2 1 EF-hand domain Abhydrolase_9 PF10081.9 AIO02830.1 - 0.02 14.0 0.2 0.028 13.5 0.2 1.1 1 0 0 1 1 1 0 Alpha/beta-hydrolase family EF-hand_5 PF13202.6 AIO02830.1 - 0.04 13.4 0.4 0.4 10.2 0.0 2.6 3 0 0 3 3 3 0 EF hand RNA_lig_T4_1 PF09511.10 AIO02832.1 - 2e-30 106.3 0.0 3.9e-30 105.4 0.0 1.5 1 0 0 1 1 1 1 RNA ligase AAA_33 PF13671.6 AIO02832.1 - 4.8e-11 43.0 0.5 4.8e-11 43.0 0.5 2.1 2 0 0 2 2 2 1 AAA domain 6PF2K PF01591.18 AIO02832.1 - 3.6e-08 33.0 0.0 6.6e-08 32.1 0.0 1.3 1 0 0 1 1 1 1 6-phosphofructo-2-kinase AAA_18 PF13238.6 AIO02832.1 - 1.6e-06 28.7 0.0 3.9e-06 27.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain APS_kinase PF01583.20 AIO02832.1 - 0.00072 19.5 0.0 0.0024 17.8 0.0 1.9 1 1 0 1 1 1 1 Adenylylsulphate kinase KTI12 PF08433.10 AIO02832.1 - 0.0018 17.8 0.0 0.0033 16.9 0.0 1.3 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_17 PF13207.6 AIO02832.1 - 0.002 18.6 0.0 0.0043 17.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain NACHT PF05729.12 AIO02832.1 - 0.0029 17.5 0.0 0.0081 16.1 0.0 1.8 1 0 0 1 1 1 1 NACHT domain AAA_25 PF13481.6 AIO02832.1 - 0.0092 15.6 1.7 0.027 14.0 0.2 2.5 1 1 1 2 2 2 1 AAA domain CPT PF07931.12 AIO02832.1 - 0.022 14.6 0.6 0.061 13.2 0.2 2.0 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein AAA_28 PF13521.6 AIO02832.1 - 0.026 14.8 0.3 0.087 13.1 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 AIO02832.1 - 0.049 14.0 1.2 0.16 12.3 0.8 2.3 1 1 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 AIO02832.1 - 0.052 13.8 0.1 0.26 11.5 0.0 2.1 1 1 1 2 2 2 0 AAA domain Zeta_toxin PF06414.12 AIO02832.1 - 0.059 12.6 0.0 0.17 11.1 0.0 1.8 2 0 0 2 2 2 0 Zeta toxin ABC_tran PF00005.27 AIO02832.1 - 0.072 13.6 0.0 0.29 11.6 0.0 2.0 2 0 0 2 2 1 0 ABC transporter AAA_5 PF07728.14 AIO02832.1 - 0.094 12.7 0.0 0.27 11.2 0.0 1.8 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.17 AIO02832.1 - 0.11 12.2 0.0 0.25 11.0 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein MMR_HSR1 PF01926.23 AIO02832.1 - 0.16 12.1 0.0 0.37 10.9 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase EVE PF01878.18 AIO02834.1 - 7.9e-53 178.4 0.7 9e-53 178.2 0.7 1.0 1 0 0 1 1 1 1 EVE domain Bromodomain PF00439.25 AIO02835.1 - 7e-18 64.5 0.1 1.3e-17 63.6 0.1 1.5 1 0 0 1 1 1 1 Bromodomain Nucleoporin_N PF08801.11 AIO02836.1 - 8.2e-59 199.5 0.0 1.4e-58 198.7 0.0 1.3 1 0 0 1 1 1 1 Nup133 N terminal like Phospholamban PF04272.14 AIO02836.1 - 0.1 12.1 1.8 7 6.2 0.4 2.6 2 0 0 2 2 2 0 Phospholamban LRR_4 PF12799.7 AIO02837.1 - 0.0022 18.4 0.0 0.11 12.9 0.0 2.6 2 0 0 2 2 2 1 Leucine Rich repeats (2 copies) Cpn60_TCP1 PF00118.24 AIO02838.1 - 2.6e-150 501.3 9.6 2.9e-150 501.1 9.6 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family DUF374 PF04028.13 AIO02838.1 - 0.13 11.8 0.1 0.85 9.2 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF374) Ribosomal_L1 PF00687.21 AIO02839.1 - 4.1e-20 72.4 0.0 5.4e-20 72.0 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family zf-C2H2_6 PF13912.6 AIO02840.1 - 5.6e-05 23.0 12.5 0.00038 20.4 2.5 2.4 2 0 0 2 2 2 2 C2H2-type zinc finger zf-met PF12874.7 AIO02840.1 - 0.0088 16.4 6.7 0.48 10.9 0.7 2.7 2 0 0 2 2 2 2 Zinc-finger of C2H2 type SSB PF00436.25 AIO02840.1 - 0.013 15.5 0.0 0.028 14.4 0.0 1.5 1 0 0 1 1 1 0 Single-strand binding protein family zf-C2H2_2 PF12756.7 AIO02840.1 - 0.018 15.4 1.1 1.8 9.0 0.1 2.3 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.6 AIO02840.1 - 0.049 14.5 12.6 0.35 11.8 3.4 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger Flag1_repress PF03614.13 AIO02840.1 - 0.07 12.9 0.0 2.5 7.9 0.0 2.5 2 0 0 2 2 2 0 Repressor of phase-1 flagellin zf-Di19 PF05605.12 AIO02840.1 - 0.071 13.4 3.4 2 8.7 0.2 2.4 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2 PF00096.26 AIO02840.1 - 0.2 12.2 11.1 1.5 9.4 3.5 2.7 2 0 0 2 2 2 0 Zinc finger, C2H2 type DUF629 PF04780.12 AIO02840.1 - 0.31 9.5 1.7 1.9 6.9 0.3 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF629) zf_C2H2_ZHX PF18387.1 AIO02840.1 - 0.32 10.7 3.2 1.2 8.8 0.3 2.3 2 0 0 2 2 2 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-C2H2_jaz PF12171.8 AIO02840.1 - 1.3 9.4 5.2 14 6.1 0.3 2.5 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-H2C2_2 PF13465.6 AIO02840.1 - 2.9 8.5 8.3 2.7 8.6 0.2 3.2 3 0 0 3 3 3 0 Zinc-finger double domain Thioredoxin PF00085.20 AIO02842.1 - 5.6e-60 199.7 1.4 1.1e-30 105.6 0.1 3.9 4 0 0 4 4 4 2 Thioredoxin Thioredoxin_6 PF13848.6 AIO02842.1 - 2.4e-28 99.3 0.2 2.8e-19 69.7 0.0 3.3 2 1 1 3 3 3 3 Thioredoxin-like domain Thioredoxin_2 PF13098.6 AIO02842.1 - 2.6e-15 56.8 2.4 7.9e-08 32.7 0.2 3.6 2 2 0 2 2 2 2 Thioredoxin-like domain AhpC-TSA PF00578.21 AIO02842.1 - 6.4e-11 42.3 1.1 6.2e-05 22.9 0.0 3.6 4 0 0 4 4 4 2 AhpC/TSA family Thioredoxin_7 PF13899.6 AIO02842.1 - 3.8e-10 39.8 0.1 0.00024 21.2 0.0 3.3 3 0 0 3 3 3 2 Thioredoxin-like Thioredoxin_8 PF13905.6 AIO02842.1 - 1.2e-09 38.3 1.9 0.036 14.4 0.0 5.0 4 2 2 6 6 6 3 Thioredoxin-like OST3_OST6 PF04756.13 AIO02842.1 - 9.2e-07 28.5 0.1 0.0018 17.7 0.0 2.7 2 1 1 3 3 3 2 OST3 / OST6 family, transporter family TraF PF13728.6 AIO02842.1 - 9.6e-06 25.6 0.1 0.014 15.2 0.0 3.4 3 1 0 3 3 3 1 F plasmid transfer operon protein Thioredoxin_9 PF14595.6 AIO02842.1 - 1.5e-05 24.7 0.0 0.089 12.6 0.0 2.7 3 0 0 3 3 3 2 Thioredoxin Redoxin PF08534.10 AIO02842.1 - 9.5e-05 22.1 1.2 0.0085 15.8 0.0 3.2 3 0 0 3 3 3 1 Redoxin Thioredoxin_3 PF13192.6 AIO02842.1 - 0.00014 21.9 0.6 0.43 10.6 0.1 3.4 3 0 0 3 3 3 2 Thioredoxin domain HyaE PF07449.11 AIO02842.1 - 0.017 15.1 0.0 0.21 11.6 0.0 2.5 2 0 0 2 2 2 0 Hydrogenase-1 expression protein HyaE Sigma70_r4_2 PF08281.12 AIO02842.1 - 0.16 11.6 0.0 0.36 10.5 0.0 1.6 1 0 0 1 1 1 0 Sigma-70, region 4 FleQ PF06490.11 AIO02842.1 - 0.17 12.2 0.0 0.73 10.2 0.0 2.0 2 0 0 2 2 2 0 Flagellar regulatory protein FleQ FA_desaturase PF00487.24 AIO02843.1 - 7.8e-32 111.1 14.5 1.2e-31 110.4 14.5 1.3 1 0 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.28 AIO02843.1 - 8.4e-10 38.7 0.0 1.6e-09 37.7 0.0 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain DUF3788 PF12663.7 AIO02844.1 - 0.095 12.7 0.1 0.34 10.9 0.1 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3788) KASH_CCD PF14662.6 AIO02844.1 - 0.86 9.4 36.7 0.074 12.9 2.1 4.6 1 1 0 4 4 4 0 Coiled-coil region of CCDC155 or KASH eIF3_N PF09440.10 AIO02844.1 - 1.2 9.6 19.3 0.33 11.4 0.3 3.9 1 1 1 3 3 3 0 eIF3 subunit 6 N terminal domain Mt_ATP-synt_D PF05873.12 AIO02844.1 - 1.6 8.6 7.4 0.93 9.3 0.4 3.3 2 1 1 4 4 4 0 ATP synthase D chain, mitochondrial (ATP5H) Methyltransf_23 PF13489.6 AIO02845.1 - 0.032 14.1 0.0 0.041 13.7 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain DUF3285 PF11688.8 AIO02845.1 - 0.058 13.3 0.0 0.1 12.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3285) eIF-3c_N PF05470.12 AIO02846.1 - 6.1e-21 74.4 1.6 1.5e-15 56.6 0.0 2.3 2 1 0 2 2 2 2 Eukaryotic translation initiation factor 3 subunit 8 N-terminus PCI PF01399.27 AIO02846.1 - 0.022 15.3 0.1 0.1 13.1 0.0 2.2 2 0 0 2 2 2 0 PCI domain 6PF2K PF01591.18 AIO02846.1 - 0.059 12.7 0.4 0.25 10.6 0.1 1.9 2 0 0 2 2 2 0 6-phosphofructo-2-kinase RRM_1 PF00076.22 AIO02847.1 - 0.0038 17.0 0.0 0.0085 15.9 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.8 AIO02847.1 - 0.02 15.0 0.0 0.032 14.3 0.0 1.3 1 0 0 1 1 1 0 Limkain b1 RRM_5 PF13893.6 AIO02847.1 - 0.032 13.8 0.0 0.046 13.3 0.0 1.3 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) MOZ_SAS PF01853.18 AIO02848.1 - 1.4e-46 158.4 0.0 1.7e-46 158.1 0.0 1.1 1 0 0 1 1 1 1 MOZ/SAS family zf-MYST PF17772.1 AIO02848.1 - 0.0045 16.6 0.1 0.0079 15.8 0.1 1.4 1 0 0 1 1 1 1 MYST family zinc finger domain zf-C4_ClpX PF06689.13 AIO02848.1 - 0.0073 16.2 0.7 0.015 15.2 0.2 1.8 2 0 0 2 2 2 1 ClpX C4-type zinc finger Acetyltransf_7 PF13508.7 AIO02848.1 - 0.055 13.9 0.0 0.12 12.8 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain PSP1 PF04468.12 AIO02850.1 - 1.6e-27 95.6 0.2 3e-27 94.7 0.2 1.5 1 0 0 1 1 1 1 PSP1 C-terminal conserved region # # Program: hmmscan # Version: 3.2.1 (June 2018) # Pipeline mode: SCAN # Query file: /oak/stanford/groups/akundaje/marinovg/genomes/Kinetoplastida/Leishmania_panamensis-ASM75516v1/GCA_000755165.1_ASM75516v1_protein.faa # Target file: /oak/stanford/groups/akundaje/marinovg/genomes/PFam/PFam32.0/Pfam-A.hmm # Option settings: /oak/stanford/groups/akundaje/marinovg/programs/hmmer-3.2.1/bin/hmmscan -o /oak/stanford/groups/akundaje/marinovg/genomes/Kinetoplastida/Leishmania_panamensis-ASM75516v1/GCA_000755165.1_ASM75516v1_protein.PFam32-A --tblout /oak/stanford/groups/akundaje/marinovg/genomes/Kinetoplastida/Leishmania_panamensis-ASM75516v1/GCA_000755165.1_ASM75516v1_protein.PFam32-A.tblout --cpu 20 /oak/stanford/groups/akundaje/marinovg/genomes/PFam/PFam32.0/Pfam-A.hmm /oak/stanford/groups/akundaje/marinovg/genomes/Kinetoplastida/Leishmania_panamensis-ASM75516v1/GCA_000755165.1_ASM75516v1_protein.faa # Current dir: /oak/stanford/groups/akundaje/marinovg/genomes # Date: Mon Mar 25 08:33:45 2019 # [ok]