# --- full sequence ---- --- best 1 domain ---- --- domain number estimation ---- # target name accession query name accession E-value score bias E-value score bias exp reg clu ov env dom rep inc description of target #------------------- ---------- -------------------- ---------- --------- ------ ----- --------- ------ ----- --- --- --- --- --- --- --- --- --------------------- DUF2946 PF11162.3 AIN95102.1 - 1.4e-15 57.5 0.2 2.4e-15 56.8 0.2 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2946) Rhabdo_glycop PF00974.13 AIN95102.1 - 0.00011 20.5 0.2 0.00018 19.9 0.1 1.2 1 0 0 1 1 1 1 Rhabdovirus spike glycoprotein Shisa PF13908.1 AIN95102.1 - 0.015 15.4 0.0 0.035 14.2 0.0 1.6 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator Orthoreo_P10 PF07204.6 AIN95102.1 - 0.025 14.3 0.2 0.074 12.7 0.1 1.8 1 0 0 1 1 1 0 Orthoreovirus membrane fusion protein p10 Herpes_gE PF02480.11 AIN95102.1 - 0.031 12.5 0.0 0.049 11.9 0.0 1.3 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E Hum_adeno_E3A PF05393.6 AIN95102.1 - 0.066 12.8 0.6 0.17 11.5 0.4 1.7 1 0 0 1 1 1 0 Human adenovirus early E3A glycoprotein EphA2_TM PF14575.1 AIN95102.1 - 0.18 12.2 0.2 0.61 10.5 0.0 1.9 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Tweety PF04906.8 AIN95102.1 - 0.5 8.7 5.5 0.32 9.3 0.5 2.0 2 0 0 2 2 2 0 Tweety Exo_endo_phos PF03372.18 AIN95103.1 - 3.5e-11 43.5 0.2 5.7e-11 42.8 0.1 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Kinesin PF00225.18 AIN95104.1 - 1.6e-94 316.3 0.0 2.2e-94 315.9 0.0 1.1 1 0 0 1 1 1 1 Kinesin motor domain SAM_1 PF00536.25 AIN95104.1 - 0.024 14.8 0.0 0.043 13.9 0.0 1.5 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) GYF PF02213.11 AIN95105.1 - 0.0011 18.4 0.2 0.002 17.7 0.1 1.3 1 0 0 1 1 1 1 GYF domain CPSase_L_D2 PF02786.12 AIN95106.1 - 1.9e-77 259.2 1.1 3e-77 258.6 0.4 1.6 2 0 0 2 2 2 1 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_chain PF00289.17 AIN95106.1 - 2.4e-41 140.2 0.8 9.9e-41 138.2 0.1 2.2 2 0 0 2 2 2 1 Carbamoyl-phosphate synthase L chain, N-terminal domain Biotin_carb_C PF02785.14 AIN95106.1 - 3.9e-35 120.0 0.0 1.2e-34 118.4 0.0 1.9 2 0 0 2 2 2 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.17 AIN95106.1 - 1.7e-15 56.4 3.4 1.7e-15 56.4 2.3 2.1 2 0 0 2 2 2 1 Biotin-requiring enzyme ATP-grasp_4 PF13535.1 AIN95106.1 - 2.4e-14 53.4 0.1 5.9e-14 52.2 0.1 1.6 1 0 0 1 1 1 1 ATP-grasp domain ATPgrasp_Ter PF15632.1 AIN95106.1 - 1.1e-11 44.1 0.9 1.6e-11 43.5 0.6 1.2 1 0 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp PF02222.17 AIN95106.1 - 2.5e-08 33.4 0.6 1e-07 31.4 0.2 2.0 2 0 0 2 2 2 1 ATP-grasp domain Biotin_lipoyl_2 PF13533.1 AIN95106.1 - 8e-08 31.8 1.7 1.7e-06 27.6 0.3 2.9 2 1 1 3 3 3 1 Biotin-lipoyl like Dala_Dala_lig_C PF07478.8 AIN95106.1 - 1.8e-06 27.5 0.1 4.2e-06 26.2 0.1 1.6 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp_3 PF02655.9 AIN95106.1 - 9e-05 22.3 0.2 0.00016 21.5 0.1 1.5 1 0 0 1 1 1 1 ATP-grasp domain ATPgrasp_ST PF14397.1 AIN95106.1 - 0.00068 18.8 0.0 0.0015 17.6 0.0 1.6 1 0 0 1 1 1 1 Sugar-transfer associated ATP-grasp GARS_A PF01071.14 AIN95106.1 - 0.0014 18.2 0.0 0.0029 17.1 0.0 1.5 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain HlyD_3 PF13437.1 AIN95106.1 - 0.037 14.3 2.4 0.28 11.5 0.1 2.9 2 1 1 3 3 2 0 HlyD family secretion protein GAS PF13851.1 AIN95107.1 - 0.017 14.2 2.8 0.027 13.6 1.9 1.3 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding Peptidase_M16 PF00675.15 AIN95107.1 - 0.18 11.5 3.0 0.13 12.0 0.8 1.6 2 0 0 2 2 2 0 Insulinase (Peptidase family M16) Tox-ODYAM1 PF15642.1 AIN95107.1 - 0.27 9.8 4.4 0.37 9.4 3.0 1.1 1 0 0 1 1 1 0 Toxin in Odyssella and Amoebophilus DltD_M PF04918.7 AIN95107.1 - 0.3 11.2 2.8 0.44 10.7 2.0 1.2 1 0 0 1 1 1 0 DltD central region Atg14 PF10186.4 AIN95107.1 - 0.5 9.2 6.6 0.7 8.7 4.6 1.3 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Mnd1 PF03962.10 AIN95107.1 - 5.3 6.6 9.7 2.4 7.8 5.1 1.5 2 0 0 2 2 2 0 Mnd1 family BSD PF03909.12 AIN95108.1 - 7.8e-11 41.5 0.0 1.3e-10 40.8 0.0 1.3 1 0 0 1 1 1 1 BSD domain DUF2181 PF10223.4 AIN95108.1 - 0.19 11.0 0.5 4.5 6.5 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2181) Thymidylate_kin PF02223.12 AIN95110.1 - 7.4e-32 110.2 0.0 8.9e-32 109.9 0.0 1.1 1 0 0 1 1 1 1 Thymidylate kinase AAA_33 PF13671.1 AIN95110.1 - 1.3e-05 25.1 0.0 2.9e-05 23.9 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 AIN95110.1 - 0.0002 21.6 0.0 0.00059 20.1 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 AIN95110.1 - 0.0011 18.6 2.4 0.0023 17.6 0.4 2.6 2 1 0 2 2 2 1 Part of AAA domain AAA_16 PF13191.1 AIN95110.1 - 0.0012 18.8 0.1 0.0022 18.0 0.1 1.6 1 1 0 1 1 1 1 AAA ATPase domain UPF0079 PF02367.12 AIN95110.1 - 0.011 15.3 0.0 0.028 14.0 0.0 1.7 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 AAA PF00004.24 AIN95110.1 - 0.013 15.7 0.0 0.037 14.2 0.0 1.8 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 AIN95110.1 - 0.013 16.3 0.0 0.022 15.5 0.0 1.5 1 1 0 1 1 1 0 AAA domain AAA_30 PF13604.1 AIN95110.1 - 0.022 14.3 0.2 0.071 12.6 0.0 1.9 1 1 0 1 1 1 0 AAA domain 6PF2K PF01591.13 AIN95110.1 - 0.024 13.7 0.0 0.036 13.1 0.0 1.2 1 0 0 1 1 1 0 6-phosphofructo-2-kinase AAA_22 PF13401.1 AIN95110.1 - 0.03 14.4 0.0 0.071 13.2 0.0 1.8 1 1 0 1 1 1 0 AAA domain DUF2075 PF09848.4 AIN95110.1 - 0.038 12.9 0.0 0.056 12.4 0.0 1.5 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_28 PF13521.1 AIN95110.1 - 0.045 13.7 0.4 0.094 12.6 0.3 1.6 1 1 0 1 1 1 0 AAA domain DUF853 PF05872.7 AIN95110.1 - 0.054 11.8 0.0 0.081 11.2 0.0 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) Vps39_2 PF10367.4 AIN95110.1 - 0.056 13.6 0.1 3.1 8.0 0.0 3.1 4 0 0 4 4 4 0 Vacuolar sorting protein 39 domain 2 Glyco_transf_11 PF01531.11 AIN95111.1 - 5.9e-11 41.8 0.1 4.3e-08 32.5 0.0 2.1 2 0 0 2 2 2 2 Glycosyl transferase family 11 Glutaredoxin PF00462.19 AIN95112.1 - 9.6e-18 63.9 0.2 2.4e-17 62.6 0.1 1.7 2 0 0 2 2 2 1 Glutaredoxin LSM PF01423.17 AIN95117.1 - 9.2e-09 34.7 0.0 1.1e-08 34.5 0.0 1.1 1 0 0 1 1 1 1 LSM domain Voltage_CLC PF00654.15 AIN95119.1 - 2.1e-89 299.9 31.2 3.4e-88 296.0 20.0 2.1 2 0 0 2 2 2 2 Voltage gated chloride channel CBS PF00571.23 AIN95119.1 - 1.9e-05 24.3 0.0 0.003 17.3 0.0 2.4 2 0 0 2 2 2 2 CBS domain DUF1010 PF06231.6 AIN95119.1 - 7.7 6.5 7.7 0.35 10.8 1.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1010) cwf21 PF08312.7 AIN95120.1 - 0.017 14.9 1.3 0.017 14.9 0.9 2.1 2 0 0 2 2 2 0 cwf21 domain LMWPc PF01451.16 AIN95121.1 - 9.4e-09 35.7 0.0 1.7e-08 34.8 0.0 1.5 1 0 0 1 1 1 1 Low molecular weight phosphotyrosine protein phosphatase CUE PF02845.11 AIN95122.1 - 1.4e-15 56.3 0.1 1.1e-06 28.0 0.0 4.0 4 0 0 4 4 4 3 CUE domain DUF1771 PF08590.5 AIN95122.1 - 1.8e-13 50.2 0.1 1.8e-13 50.2 0.1 2.8 3 0 0 3 3 3 1 Domain of unknown function (DUF1771) Smr PF01713.16 AIN95122.1 - 4.3e-11 42.8 0.5 1.1e-10 41.5 0.4 1.7 1 0 0 1 1 1 1 Smr domain UBA PF00627.26 AIN95122.1 - 1.3e-08 34.3 0.1 6.7e-05 22.6 0.1 2.8 2 0 0 2 2 2 2 UBA/TS-N domain Pro_isomerase PF00160.16 AIN95123.1 - 2.9e-36 125.0 0.0 4.2e-36 124.4 0.0 1.2 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD SNF2_N PF00176.18 AIN95125.1 - 2e-49 167.9 0.0 2.9e-49 167.4 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 AIN95125.1 - 3.3e-13 49.3 0.0 7.3e-13 48.1 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 AIN95125.1 - 0.0002 20.9 0.0 0.00039 19.9 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.10 AIN95125.1 - 0.0039 17.0 0.1 0.042 13.6 0.0 2.4 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit Beta_helix PF13229.1 AIN95126.1 - 8.6e-12 45.0 0.6 1.5e-11 44.2 0.4 1.4 1 0 0 1 1 1 1 Right handed beta helix region NosD PF05048.8 AIN95126.1 - 2.2e-06 27.0 0.1 3.5e-06 26.3 0.1 1.2 1 0 0 1 1 1 1 Periplasmic copper-binding protein (NosD) Enkurin PF13864.1 AIN95127.1 - 1.9e-20 72.8 6.8 1.9e-20 72.8 4.7 1.7 2 0 0 2 2 2 1 Calmodulin-binding Surfac_D-trimer PF09006.6 AIN95127.1 - 0.32 10.7 1.9 1.2 8.9 0.1 2.7 2 0 0 2 2 2 0 Lung surfactant protein D coiled-coil trimerisation Thioredoxin PF00085.15 AIN95128.1 - 3.2e-21 74.9 0.1 3.5e-21 74.8 0.0 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.1 AIN95128.1 - 6.1e-06 26.4 0.5 3.9e-05 23.8 0.4 1.9 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.1 AIN95128.1 - 9e-05 22.5 0.3 0.0041 17.2 0.1 2.1 1 1 1 2 2 2 2 Thioredoxin-like AhpC-TSA PF00578.16 AIN95128.1 - 0.01 15.4 0.1 0.012 15.2 0.0 1.2 1 0 0 1 1 1 0 AhpC/TSA family Thioredoxin_7 PF13899.1 AIN95128.1 - 0.016 15.1 0.1 0.025 14.5 0.1 1.4 1 0 0 1 1 1 0 Thioredoxin-like Phosducin PF02114.11 AIN95128.1 - 0.032 12.9 0.0 0.035 12.8 0.0 1.1 1 0 0 1 1 1 0 Phosducin Thioredoxin_6 PF13848.1 AIN95128.1 - 0.066 13.0 0.0 0.078 12.7 0.0 1.1 1 0 0 1 1 1 0 Thioredoxin-like domain DPM3 PF08285.6 AIN95128.1 - 0.079 12.8 0.0 0.36 10.7 0.0 1.9 2 0 0 2 2 2 0 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) HyaE PF07449.6 AIN95128.1 - 0.082 12.8 0.0 0.13 12.1 0.0 1.3 1 0 0 1 1 1 0 Hydrogenase-1 expression protein HyaE PseudoU_synth_2 PF00849.17 AIN95129.1 - 1.6e-21 76.8 0.0 9e-21 74.3 0.0 1.9 2 0 0 2 2 2 1 RNA pseudouridylate synthase Cmc1 PF08583.5 AIN95130.1 - 4.3e-06 26.3 3.5 7.4e-06 25.6 2.5 1.4 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like CHCH PF06747.8 AIN95130.1 - 0.027 14.3 3.2 1.2 9.1 2.2 2.4 1 1 1 2 2 2 0 CHCH domain AKAP95 PF04988.7 AIN95130.1 - 0.043 13.6 1.3 0.058 13.1 0.6 1.4 1 1 0 1 1 1 0 A-kinase anchoring protein 95 (AKAP95) DUF4125 PF13526.1 AIN95130.1 - 0.25 10.8 5.2 0.13 11.7 1.7 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF4125) Bcr-Abl_Oligo PF09036.5 AIN95130.1 - 0.88 9.5 4.5 3.5 7.6 1.7 2.3 1 1 1 2 2 2 0 Bcr-Abl oncoprotein oligomerisation domain 4F5 PF04419.9 AIN95131.1 - 5.1e-12 46.3 7.3 5.1e-12 46.3 5.1 2.0 1 1 1 2 2 2 1 4F5 protein family CCT PF06203.9 AIN95131.1 - 0.76 9.4 5.3 1.4 8.6 3.7 1.6 1 1 0 1 1 1 0 CCT motif DUF2870 PF11069.3 AIN95131.1 - 1.2 9.2 4.7 1.3 9.1 3.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2870) DHHA2 PF02833.9 AIN95132.1 - 5.5e-24 84.7 0.0 7e-23 81.2 0.0 2.1 2 0 0 2 2 2 1 DHHA2 domain DHH PF01368.15 AIN95132.1 - 1.9e-10 40.5 0.0 6.9e-10 38.7 0.0 1.8 1 1 0 1 1 1 1 DHH family Dor1 PF04124.7 AIN95133.1 - 0.085 11.2 0.0 0.11 10.9 0.0 1.1 1 0 0 1 1 1 0 Dor1-like family WD40 PF00400.27 AIN95134.1 - 3.9e-08 32.8 1.7 9.1e-06 25.3 0.2 3.0 3 0 0 3 3 3 2 WD domain, G-beta repeat DUF989 PF06181.6 AIN95135.1 - 0.037 13.1 0.1 0.044 12.8 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF989) MPC PF03650.8 AIN95136.1 - 2.6e-14 53.1 0.4 3.1e-14 52.9 0.3 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0041) DUF4018 PF13210.1 AIN95137.1 - 0.11 11.9 1.8 0.16 11.3 1.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4018) Rpn3_C PF08375.6 AIN95138.1 - 0.048 14.0 1.4 0.11 12.8 0.9 1.6 1 0 0 1 1 1 0 Proteasome regulatory subunit C-terminal Aldedh PF00171.17 AIN95138.1 - 0.051 11.9 2.3 0.079 11.2 1.6 1.2 1 0 0 1 1 1 0 Aldehyde dehydrogenase family DUF1451 PF07295.6 AIN95138.1 - 0.33 10.7 6.0 0.21 11.3 2.3 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1451) DUF788 PF05620.6 AIN95140.1 - 5.9e-36 123.8 0.0 7.2e-36 123.6 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF788) Dymeclin PF09742.4 AIN95141.1 - 6.5e-63 212.9 0.0 1.3e-62 211.9 0.0 1.5 1 1 0 1 1 1 1 Dyggve-Melchior-Clausen syndrome protein Ribosomal_S7e PF01251.13 AIN95144.1 - 1e-69 233.8 3.9 1.1e-69 233.6 2.7 1.0 1 0 0 1 1 1 1 Ribosomal protein S7e zf-UBP PF02148.14 AIN95145.1 - 3.6e-11 43.0 8.7 3.6e-11 43.0 6.0 2.5 3 0 0 3 3 1 1 Zn-finger in ubiquitin-hydrolases and other protein zf-RING_2 PF13639.1 AIN95145.1 - 3.8e-08 33.0 9.1 3.8e-08 33.0 6.3 3.0 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_3 PF13920.1 AIN95145.1 - 6.7e-06 25.6 16.4 7e-05 22.4 2.5 2.6 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 AIN95145.1 - 5.1e-05 23.3 2.5 5.1e-05 23.3 1.7 2.4 2 0 0 2 2 1 1 RING-H2 zinc finger zf-RING_5 PF14634.1 AIN95145.1 - 0.0021 17.7 6.8 0.0021 17.7 4.7 3.0 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 AIN95145.1 - 0.003 17.5 8.7 0.003 17.5 6.0 2.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 AIN95145.1 - 0.0035 16.9 8.4 0.0035 16.9 5.8 3.3 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 AIN95145.1 - 0.028 14.2 3.8 0.094 12.5 2.7 1.9 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger ArgK PF03308.11 AIN95145.1 - 0.049 12.3 1.0 0.11 11.2 0.7 1.6 1 0 0 1 1 1 0 ArgK protein Seryl_tRNA_N PF02403.17 AIN95145.1 - 0.092 12.7 6.7 0.18 11.8 4.6 1.4 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain zf-C3HC4_4 PF15227.1 AIN95145.1 - 0.4 10.5 21.2 0.52 10.2 7.9 2.6 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING Macoilin PF09726.4 AIN95145.1 - 0.48 8.6 15.0 0.43 8.7 0.6 2.0 1 1 1 2 2 2 0 Transmembrane protein RecR PF02132.10 AIN95145.1 - 2.4 7.6 10.1 0.8 9.1 0.4 3.1 3 0 0 3 3 2 0 RecR protein DUF2852 PF11014.3 AIN95145.1 - 3.9 7.4 8.3 4.7 7.1 0.1 2.8 1 1 1 2 2 2 0 Protein of unknown function (DUF2852) DUF791 PF05631.9 AIN95146.1 - 6.4e-12 44.8 3.9 6.6e-07 28.3 0.5 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF791) Isochorismatase PF00857.15 AIN95147.1 - 4.7e-23 81.9 0.0 5.8e-23 81.7 0.0 1.1 1 0 0 1 1 1 1 Isochorismatase family AAA_18 PF13238.1 AIN95148.1 - 2.5e-06 27.7 0.0 4.9e-06 26.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 AIN95148.1 - 1.6e-05 25.7 0.1 3.3e-05 24.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 AIN95148.1 - 3e-05 24.1 0.0 6.8e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain Paired_CXXCH_1 PF09699.5 AIN95148.1 - 0.0084 15.6 1.3 0.027 13.9 0.9 1.9 1 0 0 1 1 1 1 Doubled CXXCH motif (Paired_CXXCH_1) mRNA_cap_enzyme PF01331.14 AIN95148.1 - 0.0099 15.5 0.0 0.02 14.6 0.0 1.5 1 1 0 1 1 1 1 mRNA capping enzyme, catalytic domain AAA_28 PF13521.1 AIN95148.1 - 0.013 15.4 0.0 0.026 14.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA PF00004.24 AIN95148.1 - 0.041 14.0 0.0 0.073 13.2 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.1 AIN95148.1 - 0.054 13.3 0.0 0.15 11.8 0.0 1.8 1 0 0 1 1 1 0 AAA domain KTI12 PF08433.5 AIN95148.1 - 0.093 11.9 0.0 0.18 11.0 0.0 1.4 1 0 0 1 1 1 0 Chromatin associated protein KTI12 Thymidylate_kin PF02223.12 AIN95148.1 - 0.2 10.9 0.0 3.4 6.9 0.0 2.2 2 0 0 2 2 2 0 Thymidylate kinase NTPase_1 PF03266.10 AIN95148.1 - 0.35 10.5 0.0 0.61 9.7 0.0 1.4 1 0 0 1 1 1 0 NTPase Cytochrome_C7 PF14522.1 AIN95148.1 - 0.84 9.3 7.1 2.4 7.8 4.9 1.8 1 0 0 1 1 1 0 Cytochrome c7 AMP-binding PF00501.23 AIN95149.1 - 1.5e-82 277.1 0.1 2e-82 276.8 0.1 1.1 1 0 0 1 1 1 1 AMP-binding enzyme Beta_elim_lyase PF01212.16 AIN95150.1 - 3.2e-39 134.8 0.0 3.8e-39 134.5 0.0 1.1 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_1_2 PF00155.16 AIN95150.1 - 1.2e-07 31.0 0.0 1.8e-07 30.4 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II Pyridoxal_deC PF00282.14 AIN95150.1 - 0.051 12.0 0.1 0.089 11.2 0.0 1.3 1 0 0 1 1 1 0 Pyridoxal-dependent decarboxylase conserved domain AMP-binding PF00501.23 AIN95151.1 - 3.7e-87 292.4 0.0 5.2e-87 291.9 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding PF00501.23 AIN95152.1 - 1.2e-88 297.3 0.1 1.8e-88 296.7 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme DUF4476 PF14771.1 AIN95152.1 - 0.014 15.4 0.1 0.029 14.4 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4476) PGDYG PF14083.1 AIN95152.1 - 0.02 15.2 0.0 0.048 14.0 0.0 1.6 1 0 0 1 1 1 0 PGDYG protein AMP-binding PF00501.23 AIN95153.1 - 9.6e-47 159.2 0.1 1.3e-33 116.0 0.0 2.6 2 1 0 2 2 2 2 AMP-binding enzyme Nop53 PF07767.6 AIN95153.1 - 0.77 8.6 5.4 1.2 8.0 3.7 1.2 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) zf-CCHC_3 PF13917.1 AIN95155.1 - 7.6e-08 31.9 12.0 0.0026 17.4 0.2 3.6 3 0 0 3 3 3 3 Zinc knuckle zf-CCHC PF00098.18 AIN95155.1 - 0.028 14.3 1.6 0.028 14.3 1.1 3.4 3 0 0 3 3 3 0 Zinc knuckle PRP3 PF08572.5 AIN95156.1 - 2e-23 82.9 0.0 3.1e-23 82.3 0.0 1.2 1 0 0 1 1 1 1 pre-mRNA processing factor 3 (PRP3) DUF1115 PF06544.7 AIN95156.1 - 2.1e-16 59.7 0.0 3.5e-16 59.0 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1115) Mtc PF03820.12 AIN95157.1 - 6.4e-110 366.6 0.3 7.1e-110 366.4 0.2 1.0 1 0 0 1 1 1 1 Tricarboxylate carrier TctB PF07331.6 AIN95157.1 - 0.039 13.6 0.2 0.12 12.0 0.0 1.8 2 0 0 2 2 2 0 Tripartite tricarboxylate transporter TctB family DUF3792 PF12670.2 AIN95157.1 - 0.3 10.9 2.1 0.24 11.2 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3792) RNA_ligase PF09414.5 AIN95159.1 - 5e-52 176.3 0.0 7.8e-52 175.7 0.0 1.3 1 0 0 1 1 1 1 RNA ligase RabGAP-TBC PF00566.13 AIN95160.1 - 1.8e-29 102.7 0.0 1.6e-13 50.6 0.0 2.3 2 0 0 2 2 2 2 Rab-GTPase-TBC domain Asp_protease PF09668.5 AIN95161.1 - 6.6e-56 187.1 0.5 1e-55 186.6 0.4 1.3 1 0 0 1 1 1 1 Aspartyl protease Asp_protease_2 PF13650.1 AIN95161.1 - 5.2e-09 36.4 0.0 1.9e-08 34.6 0.0 2.1 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.1 AIN95161.1 - 7e-09 35.3 0.0 2e-08 33.9 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.6 AIN95161.1 - 4.1e-06 26.7 0.1 7.6e-06 25.9 0.1 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease RVP PF00077.15 AIN95161.1 - 0.00025 20.8 0.1 0.00065 19.5 0.0 1.7 2 0 0 2 2 2 1 Retroviral aspartyl protease UBA_4 PF14555.1 AIN95161.1 - 0.00058 19.3 0.2 0.0011 18.4 0.1 1.4 1 0 0 1 1 1 1 UBA-like domain DUF2369 PF10179.4 AIN95161.1 - 0.099 11.7 0.0 0.15 11.1 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2369) EF-hand_8 PF13833.1 AIN95162.1 - 0.0023 17.4 0.0 0.0046 16.5 0.0 1.5 1 0 0 1 1 1 1 EF-hand domain pair DUF1509 PF07420.6 AIN95162.1 - 0.0051 16.1 0.2 0.0092 15.3 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1509) HSP70 PF00012.15 AIN95164.1 - 1e-26 93.0 1.5 3e-23 81.6 0.1 3.8 3 1 0 3 3 3 2 Hsp70 protein MreB_Mbl PF06723.8 AIN95164.1 - 0.012 14.2 0.7 0.023 13.3 0.5 1.3 1 0 0 1 1 1 0 MreB/Mbl protein Peptidase_M16 PF00675.15 AIN95165.1 - 7.8e-42 142.5 0.0 4.8e-41 139.9 0.0 2.0 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 AIN95165.1 - 1.5e-19 70.4 0.0 2.6e-17 63.0 0.0 3.3 3 1 0 3 3 3 1 Peptidase M16 inactive domain ORC2 PF04084.9 AIN95166.1 - 0.0027 16.6 0.0 1.1 8.0 0.0 2.2 2 0 0 2 2 2 2 Origin recognition complex subunit 2 PLAC8 PF04749.12 AIN95169.1 - 6.4e-11 42.7 8.6 1.1e-10 42.0 6.0 1.4 1 0 0 1 1 1 1 PLAC8 family Alpha_GJ PF03229.8 AIN95169.1 - 0.61 10.4 4.0 1.6 9.0 0.2 2.2 1 1 1 2 2 2 0 Alphavirus glycoprotein J zf-B_box PF00643.19 AIN95169.1 - 1.3 8.9 8.8 8.2 6.4 0.2 2.9 2 0 0 2 2 2 0 B-box zinc finger PLAC8 PF04749.12 AIN95170.1 - 5.2e-11 43.0 8.6 1e-10 42.1 6.0 1.5 1 0 0 1 1 1 1 PLAC8 family zf-B_box PF00643.19 AIN95170.1 - 1.7 8.6 8.8 8 6.4 0.2 2.7 2 0 0 2 2 2 0 B-box zinc finger ThiF PF00899.16 AIN95171.1 - 1.7e-35 121.7 0.0 9.4e-35 119.3 0.0 2.0 2 0 0 2 2 2 1 ThiF family UBACT PF02134.16 AIN95171.1 - 5.3e-16 57.9 0.0 1.4e-15 56.5 0.0 1.8 1 0 0 1 1 1 1 Repeat in ubiquitin-activating (UBA) protein UBA_e1_thiolCys PF10585.4 AIN95171.1 - 8e-06 25.1 1.9 1.6e-05 24.1 1.3 1.6 1 0 0 1 1 1 1 Ubiquitin-activating enzyme active site DUF4336 PF14234.1 AIN95173.1 - 0.13 11.4 0.6 0.33 10.1 0.0 1.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4336) DEAD PF00270.24 AIN95175.1 - 8.6e-40 135.9 0.0 3.6e-39 133.9 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 AIN95175.1 - 4e-27 93.8 0.3 3.6e-26 90.8 0.1 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain CMS1 PF14617.1 AIN95175.1 - 4e-05 22.8 0.2 0.00014 21.0 0.0 1.8 2 0 0 2 2 2 1 U3-containing 90S pre-ribosomal complex subunit AAA_22 PF13401.1 AIN95175.1 - 0.11 12.6 1.9 0.22 11.6 0.3 2.4 2 2 0 2 2 2 0 AAA domain DUF3128 PF11326.3 AIN95176.1 - 0.058 13.5 0.0 0.11 12.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3128) zf-C2H2 PF00096.21 AIN95177.1 - 0.00041 20.5 1.7 0.0012 19.0 1.2 1.8 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 AIN95177.1 - 0.12 12.7 2.1 0.39 11.1 1.4 1.9 1 0 0 1 1 1 0 C2H2-type zinc finger DUF1192 PF06698.6 AIN95177.1 - 0.2 11.4 2.9 0.41 10.4 2.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1192) FYDLN_acid PF09538.5 AIN95177.1 - 0.47 11.0 2.3 1.1 9.8 1.6 1.6 1 1 0 1 1 1 0 Protein of unknown function (FYDLN_acid) BK_channel_a PF03493.13 AIN95178.1 - 1.9e-20 72.7 0.0 4e-20 71.6 0.0 1.6 1 0 0 1 1 1 1 Calcium-activated BK potassium channel alpha subunit Ion_trans_2 PF07885.11 AIN95178.1 - 9.6e-12 44.4 5.5 3.5e-11 42.6 3.8 2.0 1 0 0 1 1 1 1 Ion channel Ion_trans_2 PF07885.11 AIN95179.1 - 9.5e-11 41.2 5.3 3.4e-10 39.4 3.7 2.0 1 0 0 1 1 1 1 Ion channel BK_channel_a PF03493.13 AIN95179.1 - 4.6e-08 32.9 0.0 1.4e-05 24.9 0.0 2.4 2 0 0 2 2 2 2 Calcium-activated BK potassium channel alpha subunit Tubulin_C PF03953.12 AIN95180.1 - 4.9e-15 55.7 0.1 7.1e-15 55.1 0.0 1.2 1 0 0 1 1 1 1 Tubulin C-terminal domain Cyt-b5 PF00173.23 AIN95181.1 - 1.6e-45 152.7 0.3 6.6e-23 80.3 0.0 2.1 2 0 0 2 2 2 2 Cytochrome b5-like Heme/Steroid binding domain EFP_N PF08207.7 AIN95181.1 - 0.089 12.6 0.0 11 5.9 0.0 2.4 2 0 0 2 2 2 0 Elongation factor P (EF-P) KOW-like domain SRP14 PF02290.10 AIN95186.1 - 0.13 12.2 0.1 0.86 9.5 0.0 2.3 3 0 0 3 3 3 0 Signal recognition particle 14kD protein zf-CCCH PF00642.19 AIN95187.1 - 0.93 9.2 14.1 0.26 11.0 2.5 2.8 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Xpo1 PF08389.7 AIN95188.1 - 1.1e-24 87.0 2.6 2.2e-23 82.8 0.1 3.5 3 0 0 3 3 3 1 Exportin 1-like protein PI3_PI4_kinase PF00454.22 AIN95189.1 - 4.6e-37 127.7 0.0 1.1e-36 126.4 0.0 1.6 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FATC PF02260.15 AIN95189.1 - 1.4e-09 37.2 1.2 3.9e-09 35.7 0.0 2.4 2 0 0 2 2 2 1 FATC domain zf-met PF12874.2 AIN95190.1 - 0.00022 21.3 0.2 0.00048 20.2 0.2 1.6 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 AIN95190.1 - 0.0038 17.3 0.2 0.0089 16.1 0.1 1.7 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding Troponin PF00992.15 AIN95190.1 - 0.15 12.0 5.2 0.23 11.5 3.6 1.2 1 0 0 1 1 1 0 Troponin AdoHcyase PF05221.12 AIN95190.1 - 0.16 10.8 0.1 0.24 10.3 0.1 1.2 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase Ank_2 PF12796.2 AIN95191.1 - 3.1e-17 62.6 1.6 3e-10 40.2 0.1 2.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 AIN95191.1 - 4.1e-11 43.0 0.2 2.8e-07 30.8 0.1 3.4 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.25 AIN95191.1 - 4.3e-08 32.5 1.0 0.0014 18.3 0.1 3.7 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.1 AIN95191.1 - 8.5e-07 29.0 0.2 1.7e-05 24.8 0.0 2.8 1 1 2 3 3 3 1 Ankyrin repeats (many copies) zf-C3HC4_3 PF13920.1 AIN95191.1 - 2.2e-06 27.2 11.2 5.4e-06 25.9 7.8 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Ank_3 PF13606.1 AIN95191.1 - 0.00011 22.1 0.6 0.0015 18.5 0.0 3.1 4 0 0 4 4 4 1 Ankyrin repeat Vps51 PF08700.6 AIN95193.1 - 1.1e-09 38.0 0.0 3.4e-09 36.4 0.0 1.8 1 0 0 1 1 1 1 Vps51/Vps67 Galactosyl_T PF01762.16 AIN95194.1 - 0.0037 16.8 0.3 0.11 12.1 0.1 3.0 3 0 0 3 3 3 1 Galactosyltransferase Galactosyl_T PF01762.16 AIN95195.1 - 0.0017 17.9 0.0 0.005 16.4 0.0 1.8 1 1 0 1 1 1 1 Galactosyltransferase GlcNAc PF11397.3 AIN95196.1 - 4.2e-115 384.5 0.0 8.4e-115 383.5 0.0 1.5 2 0 0 2 2 2 1 Glycosyltransferase (GlcNAc) GlcNAc PF11397.3 AIN95197.1 - 8e-07 28.4 0.0 0.017 14.2 0.0 3.1 2 2 0 2 2 2 2 Glycosyltransferase (GlcNAc) Ras PF00071.17 AIN95198.1 - 3.3e-54 182.6 0.1 4.3e-54 182.2 0.1 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 AIN95198.1 - 4.4e-23 82.0 0.0 6.8e-23 81.4 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 AIN95198.1 - 1.4e-16 60.2 0.1 1.7e-16 59.9 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 AIN95198.1 - 1.3e-07 31.0 0.3 1.6e-07 30.6 0.2 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 AIN95198.1 - 7.2e-06 25.5 0.1 1.9e-05 24.1 0.1 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.5 AIN95198.1 - 0.00045 19.4 0.1 0.00076 18.7 0.0 1.4 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.18 AIN95198.1 - 0.0038 17.1 0.0 0.013 15.4 0.0 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase PduV-EutP PF10662.4 AIN95198.1 - 0.033 13.6 0.2 3.8 6.9 0.0 2.2 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation FeoB_N PF02421.13 AIN95198.1 - 0.044 13.0 0.1 1.9 7.7 0.1 2.2 2 0 0 2 2 2 0 Ferrous iron transport protein B UPF0158 PF03682.8 AIN95199.1 - 0.062 12.9 0.0 0.068 12.7 0.0 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0158) Pkinase PF00069.20 AIN95201.1 - 4.2e-50 170.3 0.0 1.6e-49 168.3 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AIN95201.1 - 1.9e-31 109.1 0.0 2.5e-31 108.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 AIN95201.1 - 9e-11 41.2 0.1 1.6e-10 40.4 0.0 1.4 2 0 0 2 2 2 1 Kinase-like ABC2_membrane_3 PF12698.2 AIN95202.1 - 1.8e-55 188.3 32.9 5.3e-36 124.3 9.6 2.9 3 0 0 3 3 3 2 ABC-2 family transporter protein ABC_tran PF00005.22 AIN95202.1 - 2.4e-46 157.4 0.0 4.8e-22 78.7 0.0 2.4 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 AIN95202.1 - 1.1e-13 51.7 0.0 0.00033 20.7 0.0 4.3 4 0 0 4 4 4 3 AAA domain AAA_23 PF13476.1 AIN95202.1 - 3.7e-08 33.9 0.0 0.0016 18.8 0.0 2.2 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.1 AIN95202.1 - 7.5e-07 28.5 0.0 0.0028 17.1 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain SMC_N PF02463.14 AIN95202.1 - 2.7e-05 23.5 0.1 2 7.5 0.0 3.8 3 1 0 4 4 4 2 RecF/RecN/SMC N terminal domain DUF258 PF03193.11 AIN95202.1 - 0.0013 17.9 0.2 0.15 11.2 0.0 2.6 2 1 0 2 2 2 1 Protein of unknown function, DUF258 AAA_10 PF12846.2 AIN95202.1 - 0.0051 16.2 0.2 0.99 8.7 0.1 2.8 3 0 0 3 3 3 1 AAA-like domain AAA_25 PF13481.1 AIN95202.1 - 0.0059 16.0 1.4 0.24 10.8 0.0 2.9 3 0 0 3 3 2 1 AAA domain AAA_30 PF13604.1 AIN95202.1 - 0.01 15.4 0.1 3.1 7.3 0.0 2.5 2 0 0 2 2 2 0 AAA domain MukB PF04310.7 AIN95202.1 - 0.049 12.9 0.2 5.5 6.2 0.0 2.8 2 0 0 2 2 2 0 MukB N-terminal AAA_15 PF13175.1 AIN95202.1 - 0.079 11.9 0.0 9 5.2 0.0 2.6 3 0 0 3 3 3 0 AAA ATPase domain RNA_helicase PF00910.17 AIN95202.1 - 0.085 13.0 0.1 22 5.3 0.0 2.7 3 0 0 3 3 2 0 RNA helicase UPF0079 PF02367.12 AIN95202.1 - 0.098 12.2 0.0 1.2 8.8 0.0 2.2 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 AAA_17 PF13207.1 AIN95202.1 - 0.15 12.8 0.0 3.6 8.4 0.0 2.6 2 0 0 2 2 2 0 AAA domain Spore_III_AF PF09581.5 AIN95202.1 - 0.42 10.4 0.0 0.88 9.4 0.0 1.5 1 0 0 1 1 1 0 Stage III sporulation protein AF (Spore_III_AF) SRP54 PF00448.17 AIN95202.1 - 0.99 8.8 2.1 4.4 6.7 0.1 2.2 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain DUF87 PF01935.12 AIN95202.1 - 1.8 8.3 0.5 6.3 6.5 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function DUF87 DUF1049 PF06305.6 AIN95202.1 - 4.2 6.9 10.3 0.11 12.0 1.2 3.0 2 0 0 2 2 1 0 Protein of unknown function (DUF1049) AAA_13 PF13166.1 AIN95202.1 - 4.6 5.5 0.3 54 2.0 0.1 2.0 2 0 0 2 2 2 0 AAA domain DUF3584 PF12128.3 AIN95202.1 - 7.6 3.7 0.1 13 2.9 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) SNAP PF14938.1 AIN95203.1 - 6.6e-12 45.1 12.0 7.4e-10 38.4 2.8 2.9 2 1 1 3 3 3 2 Soluble NSF attachment protein, SNAP DUF1500 PF07389.7 AIN95203.1 - 0.087 12.8 0.0 0.18 11.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1500) RNase_PH PF01138.16 AIN95204.1 - 3.9e-17 62.7 0.0 1.2e-16 61.2 0.0 1.7 2 0 0 2 2 2 1 3' exoribonuclease family, domain 1 UAA PF08449.6 AIN95205.1 - 4.8e-23 81.5 10.6 2.1e-12 46.5 1.2 4.3 4 0 0 4 4 4 4 UAA transporter family TPT PF03151.11 AIN95205.1 - 7.4e-08 32.1 2.4 7.4e-08 32.1 1.6 3.1 3 0 0 3 3 3 1 Triose-phosphate Transporter family EamA PF00892.15 AIN95205.1 - 1.1e-05 25.4 4.3 1.1e-05 25.4 3.0 3.1 5 0 0 5 5 5 1 EamA-like transporter family Pkinase PF00069.20 AIN95207.1 - 2.4e-52 177.6 0.0 3.1e-52 177.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AIN95207.1 - 8.4e-21 74.2 0.0 1.2e-20 73.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 AIN95207.1 - 3.5e-07 30.2 0.2 0.00032 20.4 0.1 2.4 1 1 1 2 2 2 2 Phosphotransferase enzyme family RIO1 PF01163.17 AIN95207.1 - 0.00084 18.7 0.1 0.0014 18.0 0.1 1.2 1 0 0 1 1 1 1 RIO1 family PCI PF01399.22 AIN95208.1 - 2.2e-12 47.2 0.8 3.9e-12 46.3 0.1 1.8 2 0 0 2 2 2 1 PCI domain TPR_19 PF14559.1 AIN95208.1 - 0.0034 17.6 4.6 1.3 9.4 0.1 4.2 3 2 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.1 AIN95208.1 - 0.082 13.6 0.1 0.082 13.6 0.0 4.7 5 1 1 6 6 6 0 Tetratricopeptide repeat DDRGK PF09756.4 AIN95208.1 - 0.14 11.5 0.1 0.14 11.5 0.1 2.1 2 0 0 2 2 2 0 DDRGK domain TPR_20 PF14561.1 AIN95208.1 - 1.1 9.4 13.5 1.4 9.1 0.0 4.8 4 1 1 5 5 5 0 Tetratricopeptide repeat FtsJ PF01728.14 AIN95209.1 - 9.4e-63 211.4 0.0 1.2e-62 211.1 0.0 1.1 1 0 0 1 1 1 1 FtsJ-like methyltransferase UQ_con PF00179.21 AIN95210.1 - 5.3e-40 136.0 0.0 9.1e-40 135.3 0.0 1.3 2 0 0 2 2 2 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 AIN95210.1 - 0.00015 21.5 0.0 0.00022 20.9 0.0 1.4 1 1 0 1 1 1 1 Prokaryotic E2 family B PSI PF01437.20 AIN95212.1 - 2.2 8.5 10.3 0.69 10.1 3.4 2.6 2 1 0 2 2 2 0 Plexin repeat Rhomboid PF01694.17 AIN95213.1 - 0.00023 21.2 17.7 0.0072 16.3 0.5 2.9 3 1 0 3 3 3 2 Rhomboid family Porin_3 PF01459.17 AIN95214.1 - 4.6e-06 26.1 0.0 3.3e-05 23.3 0.0 2.0 1 1 0 1 1 1 1 Eukaryotic porin SLX9 PF15341.1 AIN95216.1 - 0.00087 19.7 13.7 0.013 15.8 9.5 2.6 1 1 0 1 1 1 1 Ribosome biogenesis protein SLX9 Gly_kinase PF02595.10 AIN95218.1 - 6.2e-26 90.9 17.4 4.3e-06 25.6 0.6 7.3 7 0 0 7 7 7 7 Glycerate kinase family FGE-sulfatase PF03781.11 AIN95219.1 - 0.0074 15.6 0.5 0.0096 15.3 0.3 1.2 1 0 0 1 1 1 1 Sulfatase-modifying factor enzyme 1 GATA-N PF05349.7 AIN95219.1 - 0.047 13.8 0.2 0.056 13.6 0.1 1.3 1 0 0 1 1 1 0 GATA-type transcription activator, N-terminal Pkinase PF00069.20 AIN95225.1 - 7.5e-59 198.9 0.0 2.2e-58 197.4 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AIN95225.1 - 1e-35 123.0 0.0 2.5e-30 105.4 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 AIN95225.1 - 3.8e-05 22.7 0.0 0.0002 20.3 0.0 1.9 2 0 0 2 2 2 1 Kinase-like RIO1 PF01163.17 AIN95225.1 - 0.0005 19.4 0.1 0.0012 18.2 0.0 1.6 2 0 0 2 2 2 1 RIO1 family APH PF01636.18 AIN95225.1 - 0.00071 19.3 0.6 0.0015 18.3 0.0 1.9 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.9 AIN95225.1 - 0.084 11.9 0.0 0.15 11.0 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family IncA PF04156.9 AIN95225.1 - 0.12 11.9 0.6 0.43 10.1 0.4 1.9 1 0 0 1 1 1 0 IncA protein TraG-D_C PF12696.2 AIN95225.1 - 0.74 9.6 3.0 6.6 6.6 0.0 2.6 2 0 0 2 2 2 0 TraM recognition site of TraD and TraG Snf7 PF03357.16 AIN95226.1 - 0.002 17.5 5.4 0.0038 16.6 3.7 1.4 1 0 0 1 1 1 1 Snf7 DUF2317 PF10079.4 AIN95226.1 - 0.68 8.4 0.5 1.1 7.7 0.3 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2317) TPR_11 PF13414.1 AIN95227.1 - 5.1e-15 54.8 13.8 2.4e-07 30.2 1.4 2.4 2 0 0 2 2 2 2 TPR repeat TPR_1 PF00515.23 AIN95227.1 - 4.1e-08 32.5 3.4 6.7e-07 28.6 0.5 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.1 AIN95227.1 - 2.3e-06 26.9 0.1 7.8e-06 25.3 0.1 1.9 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_2 PF07719.12 AIN95227.1 - 5.6e-06 25.8 0.7 5.6e-06 25.8 0.5 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.1 AIN95227.1 - 0.00082 19.9 1.0 0.00082 19.9 0.7 3.9 4 1 0 4 4 2 1 Tetratricopeptide repeat TPR_7 PF13176.1 AIN95227.1 - 0.0019 17.8 1.7 0.17 11.7 0.1 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.1 AIN95227.1 - 0.0047 17.2 5.5 0.041 14.2 0.4 2.9 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_9 PF13371.1 AIN95227.1 - 0.057 13.2 4.9 4 7.3 1.8 3.1 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.1 AIN95227.1 - 0.12 13.0 0.5 0.12 13.0 0.3 3.9 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_17 PF13431.1 AIN95227.1 - 0.23 11.7 0.1 0.23 11.7 0.1 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.1 AIN95227.1 - 2.9 7.9 12.8 2.2 8.2 0.8 3.1 1 1 2 3 3 3 0 Tetratricopeptide repeat ARPC4 PF05856.7 AIN95228.1 - 2.7e-58 196.1 0.0 3e-58 195.9 0.0 1.0 1 0 0 1 1 1 1 ARP2/3 complex 20 kDa subunit (ARPC4) V-SNARE PF05008.10 AIN95229.1 - 0.055 13.6 1.4 0.055 13.6 1.0 3.1 3 1 1 4 4 4 0 Vesicle transport v-SNARE protein N-terminus DUF1776 PF08643.5 AIN95229.1 - 0.13 11.3 0.0 0.21 10.6 0.0 1.3 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) Cauli_DNA-bind PF03310.8 AIN95229.1 - 0.13 12.1 1.0 0.23 11.2 0.7 1.5 1 0 0 1 1 1 0 Caulimovirus DNA-binding protein FlaC_arch PF05377.6 AIN95229.1 - 0.34 10.8 6.1 0.093 12.6 1.1 2.4 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) CASP_C PF08172.7 AIN95229.1 - 0.49 9.3 11.1 0.078 11.9 0.5 2.5 2 1 1 3 3 3 0 CASP C terminal MAD PF05557.8 AIN95229.1 - 2.7 5.9 22.6 0.91 7.5 6.6 2.1 1 1 1 2 2 2 0 Mitotic checkpoint protein Jnk-SapK_ap_N PF09744.4 AIN95229.1 - 7.7 6.4 22.1 0.2 11.6 5.7 2.4 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 DivIC PF04977.10 AIN95229.1 - 9.2 5.8 22.2 0.05 13.0 2.6 3.2 2 2 1 3 3 3 0 Septum formation initiator WD40 PF00400.27 AIN95230.1 - 0.00023 20.8 1.9 0.007 16.2 0.4 3.2 2 1 0 2 2 2 1 WD domain, G-beta repeat Adeno_E1B_55K PF01696.12 AIN95230.1 - 0.0072 14.8 0.1 0.01 14.3 0.1 1.1 1 0 0 1 1 1 1 Adenovirus EB1 55K protein / large t-antigen Aldedh PF00171.17 AIN95231.1 - 1.9e-07 29.7 1.3 0.00029 19.3 0.0 2.5 2 1 1 3 3 3 2 Aldehyde dehydrogenase family Nop14 PF04147.7 AIN95233.1 - 1.1e-41 142.7 7.5 7.8e-28 96.9 0.0 2.9 1 1 1 2 2 2 2 Nop14-like family Mito_carr PF00153.22 AIN95234.1 - 1.6e-28 98.2 4.4 2.8e-14 52.5 0.2 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein LRR_4 PF12799.2 AIN95235.1 - 9.1e-56 184.7 0.0 0.002 17.6 0.1 17.5 10 3 6 19 19 19 17 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 AIN95235.1 - 6.1e-16 56.0 27.7 0.78 10.0 0.0 20.0 25 0 0 25 25 25 3 Leucine Rich Repeat LRR_8 PF13855.1 AIN95235.1 - 4.3e-13 48.8 15.5 0.48 10.2 0.0 10.6 6 4 4 13 13 13 4 Leucine rich repeat LRR_5 PF13306.1 AIN95235.1 - 4.4e-06 26.4 0.1 16 5.2 0.0 5.9 4 1 0 5 5 5 2 Leucine rich repeats (6 copies) 2-Hacid_dh_C PF02826.14 AIN95237.1 - 5e-54 182.1 0.1 7.4e-54 181.5 0.1 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 AIN95237.1 - 4.3e-34 116.8 0.1 6.1e-34 116.3 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 AIN95237.1 - 2.7e-06 27.3 0.4 4.9e-06 26.4 0.3 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase IlvN PF07991.7 AIN95237.1 - 0.0062 15.9 0.2 0.012 14.9 0.1 1.5 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain AdoHcyase_NAD PF00670.16 AIN95237.1 - 0.013 15.2 0.6 0.025 14.4 0.4 1.4 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain XdhC_C PF13478.1 AIN95237.1 - 0.037 14.3 0.0 0.11 12.7 0.0 1.8 2 0 0 2 2 2 0 XdhC Rossmann domain UDPG_MGDP_dh_N PF03721.9 AIN95237.1 - 0.051 12.9 1.3 0.11 11.8 0.9 1.6 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Aminotran_5 PF00266.14 AIN95238.1 - 1.2e-21 76.9 0.0 1.5e-21 76.5 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-V Met_10 PF02475.11 AIN95239.1 - 2.7e-40 138.0 0.0 1.7e-36 125.6 0.0 2.1 2 0 0 2 2 2 2 Met-10+ like-protein Methyltransf_26 PF13659.1 AIN95239.1 - 5.6e-07 29.6 0.1 1.8e-06 27.9 0.0 2.0 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 AIN95239.1 - 2.6e-05 24.7 0.0 5.1e-05 23.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 AIN95239.1 - 5.9e-05 22.5 0.0 0.00011 21.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_31 PF13847.1 AIN95239.1 - 0.00016 21.2 0.0 0.0005 19.6 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_15 PF09445.5 AIN95239.1 - 0.00051 19.6 0.0 0.0008 19.0 0.0 1.3 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase UPF0020 PF01170.13 AIN95239.1 - 0.03 13.8 0.0 0.053 13.0 0.0 1.4 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 tRNA_U5-meth_tr PF05958.6 AIN95239.1 - 0.058 12.0 0.0 0.098 11.3 0.0 1.3 1 0 0 1 1 1 0 tRNA (Uracil-5-)-methyltransferase Acyltransferase PF01553.16 AIN95241.1 - 2.6e-14 52.7 0.0 9.9e-14 50.9 0.0 2.0 1 1 0 1 1 1 1 Acyltransferase HopW1-1 PF15457.1 AIN95241.1 - 0.043 12.8 0.0 0.075 12.0 0.0 1.3 1 0 0 1 1 1 0 Type III T3SS secreted effector HopW1-1/HopPmaA DNA_primase_lrg PF04104.9 AIN95242.1 - 2e-77 259.9 0.0 2.7e-77 259.5 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic and archaeal DNA primase, large subunit FAM220 PF15487.1 AIN95242.1 - 0.012 14.9 0.6 0.15 11.4 0.1 2.2 2 0 0 2 2 2 0 FAM220 family CtaG_Cox11 PF04442.9 AIN95243.1 - 1.1e-41 142.2 0.1 1.2e-41 142.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein CtaG/Cox11 Sec2p PF06428.6 AIN95244.1 - 0.089 12.6 0.0 0.089 12.6 0.0 3.3 4 0 0 4 4 4 0 GDP/GTP exchange factor Sec2p Cep57_MT_bd PF06657.8 AIN95244.1 - 1.7 8.6 9.7 0.29 11.1 0.2 3.5 3 0 0 3 3 3 0 Centrosome microtubule-binding domain of Cep57 LRR_4 PF12799.2 AIN95245.1 - 1.5e-16 59.6 11.9 1.7e-05 24.2 0.1 4.5 3 1 1 4 4 4 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 AIN95245.1 - 2.7e-08 33.4 13.4 0.0029 17.3 0.6 4.0 4 0 0 4 4 4 3 Leucine rich repeat LRR_9 PF14580.1 AIN95245.1 - 2e-05 24.2 3.2 0.0036 16.8 0.2 2.2 1 1 1 2 2 2 2 Leucine-rich repeat LRR_1 PF00560.28 AIN95245.1 - 3.5e-05 23.2 13.6 0.53 10.5 0.1 6.6 6 1 0 6 6 6 1 Leucine Rich Repeat LRR_7 PF13504.1 AIN95245.1 - 0.00076 19.2 14.7 0.31 11.4 0.0 6.5 7 0 0 7 7 6 2 Leucine rich repeat DUF4530 PF15039.1 AIN95245.1 - 0.0036 17.1 0.1 0.014 15.2 0.1 2.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4530) TMF_TATA_bd PF12325.3 AIN95245.1 - 0.1 12.3 7.6 0.21 11.3 5.3 1.5 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding LRR_6 PF13516.1 AIN95245.1 - 0.17 12.0 11.6 12 6.3 0.0 6.0 6 1 1 7 7 7 0 Leucine Rich repeat Tup_N PF08581.5 AIN95245.1 - 0.21 11.8 5.8 1.4 9.1 0.8 2.5 2 0 0 2 2 2 0 Tup N-terminal Filament PF00038.16 AIN95245.1 - 0.35 10.2 13.5 0.14 11.6 7.6 1.6 2 0 0 2 2 2 0 Intermediate filament protein HALZ PF02183.13 AIN95245.1 - 0.98 9.1 5.0 1.1 8.9 0.6 2.8 2 1 0 2 2 2 0 Homeobox associated leucine zipper APG6 PF04111.7 AIN95245.1 - 1.1 8.1 7.7 1.8 7.5 5.4 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 Spc7 PF08317.6 AIN95245.1 - 1.3 7.5 5.7 2.1 6.8 3.9 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein GAS PF13851.1 AIN95245.1 - 5.5 6.1 8.1 9.3 5.3 5.6 1.3 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding Acetyltransf_1 PF00583.19 AIN95246.1 - 1.9e-08 34.1 0.0 2.7e-08 33.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 AIN95246.1 - 0.00019 21.5 0.1 0.00035 20.6 0.1 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain DUF4257 PF14074.1 AIN95246.1 - 0.013 15.0 0.2 0.11 12.1 0.0 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF4257) Acetyltransf_4 PF13420.1 AIN95246.1 - 0.014 15.3 0.1 0.019 14.9 0.1 1.1 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain DUF4558 PF15104.1 AIN95247.1 - 2.9e-05 23.9 4.6 4e-05 23.4 3.2 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF4558) FMN_dh PF01070.13 AIN95247.1 - 0.022 13.5 0.1 0.049 12.4 0.0 1.5 1 1 1 2 2 2 0 FMN-dependent dehydrogenase ABC_tran PF00005.22 AIN95249.1 - 2.6e-47 160.5 5.2 3.3e-23 82.4 0.0 3.7 4 0 0 4 4 3 2 ABC transporter ABC_tran_2 PF12848.2 AIN95249.1 - 5.5e-24 83.8 3.6 5.5e-24 83.8 2.5 2.9 4 0 0 4 4 2 1 ABC transporter AAA_21 PF13304.1 AIN95249.1 - 6.1e-18 65.8 8.4 0.00029 20.8 0.3 4.6 4 1 1 5 5 5 4 AAA domain SMC_N PF02463.14 AIN95249.1 - 3.3e-11 42.8 0.8 0.0056 15.9 0.0 4.2 2 2 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 AIN95249.1 - 1.4e-08 34.1 0.3 0.0013 18.2 0.0 2.9 3 0 0 3 3 2 2 P-loop containing region of AAA domain AAA_17 PF13207.1 AIN95249.1 - 2.9e-08 34.5 0.3 0.00024 21.8 0.0 3.1 3 1 0 3 3 2 2 AAA domain DUF258 PF03193.11 AIN95249.1 - 5.3e-08 32.2 0.2 0.00068 18.8 0.1 2.5 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_15 PF13175.1 AIN95249.1 - 7.8e-08 31.7 4.7 0.47 9.4 0.0 4.8 3 1 0 4 4 4 3 AAA ATPase domain AAA_16 PF13191.1 AIN95249.1 - 8.1e-08 32.4 0.6 0.0046 16.9 0.2 2.7 2 0 0 2 2 2 2 AAA ATPase domain MMR_HSR1 PF01926.18 AIN95249.1 - 1e-06 28.6 0.2 0.046 13.6 0.0 3.0 3 0 0 3 3 2 2 50S ribosome-binding GTPase Miro PF08477.8 AIN95249.1 - 9.1e-06 26.1 0.1 0.11 13.0 0.0 2.9 3 0 0 3 3 2 2 Miro-like protein AAA_33 PF13671.1 AIN95249.1 - 2.1e-05 24.4 2.5 0.056 13.3 0.0 3.4 3 1 0 3 3 3 2 AAA domain AAA PF00004.24 AIN95249.1 - 8.8e-05 22.7 0.0 0.96 9.6 0.0 3.7 4 0 0 4 4 3 2 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.1 AIN95249.1 - 0.00015 21.7 7.0 0.018 14.9 0.0 3.3 4 0 0 4 4 2 2 AAA domain AAA_22 PF13401.1 AIN95249.1 - 0.00015 21.9 1.7 0.29 11.2 0.1 3.5 2 2 0 2 2 2 2 AAA domain AAA_18 PF13238.1 AIN95249.1 - 0.00017 21.9 1.6 0.097 12.9 0.0 3.6 3 0 0 3 3 3 1 AAA domain PduV-EutP PF10662.4 AIN95249.1 - 0.00019 20.9 0.1 0.057 12.9 0.0 2.6 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation NACHT PF05729.7 AIN95249.1 - 0.00023 20.8 0.1 0.5 10.0 0.0 2.6 2 0 0 2 2 2 2 NACHT domain Dynamin_N PF00350.18 AIN95249.1 - 0.00027 20.8 0.0 2.6 7.8 0.0 3.7 3 0 0 3 3 3 1 Dynamin family AAA_23 PF13476.1 AIN95249.1 - 0.00027 21.3 10.4 0.081 13.2 0.0 4.2 5 0 0 5 5 4 2 AAA domain AAA_14 PF13173.1 AIN95249.1 - 0.00033 20.5 0.0 1 9.2 0.0 3.5 3 0 0 3 3 3 1 AAA domain AAA_25 PF13481.1 AIN95249.1 - 0.00033 20.0 0.0 1.3 8.4 0.0 3.1 2 0 0 2 2 2 2 AAA domain MobB PF03205.9 AIN95249.1 - 0.0006 19.5 0.2 1.1 8.9 0.0 3.1 2 1 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B SbcCD_C PF13558.1 AIN95249.1 - 0.0018 18.1 0.2 0.42 10.5 0.0 3.7 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit cobW PF02492.14 AIN95249.1 - 0.0019 17.6 0.1 0.36 10.2 0.0 2.5 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain RNA_helicase PF00910.17 AIN95249.1 - 0.0025 17.9 0.0 0.82 9.8 0.0 2.8 2 0 0 2 2 2 1 RNA helicase DUF815 PF05673.8 AIN95249.1 - 0.0029 16.5 0.1 0.56 9.0 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_5 PF07728.9 AIN95249.1 - 0.003 17.2 0.1 2.7 7.7 0.0 3.1 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) Arf PF00025.16 AIN95249.1 - 0.0039 16.4 0.7 1.7 7.8 0.0 3.3 3 0 0 3 3 3 1 ADP-ribosylation factor family AAA_30 PF13604.1 AIN95249.1 - 0.0039 16.7 1.7 1.1 8.7 0.0 2.9 3 0 0 3 3 2 1 AAA domain FeoB_N PF02421.13 AIN95249.1 - 0.0057 15.9 0.1 0.24 10.6 0.0 2.4 2 0 0 2 2 2 1 Ferrous iron transport protein B UPF0079 PF02367.12 AIN95249.1 - 0.0064 16.1 0.1 0.14 11.7 0.0 2.7 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 Arch_ATPase PF01637.13 AIN95249.1 - 0.014 15.0 2.6 4.7 6.8 0.0 3.3 4 0 0 4 4 4 0 Archaeal ATPase SRP54 PF00448.17 AIN95249.1 - 0.015 14.7 0.2 4.9 6.5 0.0 2.7 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_24 PF13479.1 AIN95249.1 - 0.038 13.5 2.2 13 5.3 0.0 3.4 3 0 0 3 3 3 0 AAA domain Ras PF00071.17 AIN95249.1 - 0.042 13.2 0.1 1.1 8.5 0.0 2.5 2 0 0 2 2 2 0 Ras family NTPase_1 PF03266.10 AIN95249.1 - 0.042 13.5 0.2 11 5.6 0.0 2.9 2 0 0 2 2 2 0 NTPase FtsK_SpoIIIE PF01580.13 AIN95249.1 - 0.045 13.2 2.0 7 6.0 0.0 3.1 2 1 0 2 2 2 0 FtsK/SpoIIIE family ArgK PF03308.11 AIN95249.1 - 0.073 11.8 0.1 8.7 5.0 0.0 2.6 2 0 0 2 2 2 0 ArgK protein Septin PF00735.13 AIN95249.1 - 0.079 11.9 2.9 2.3 7.1 0.0 2.9 3 0 0 3 3 2 0 Septin AAA_10 PF12846.2 AIN95249.1 - 0.085 12.2 7.2 1.6 8.0 0.1 3.9 4 1 1 5 5 5 0 AAA-like domain U1snRNP70_N PF12220.3 AIN95249.1 - 1.8 8.9 7.3 31 4.9 1.2 3.3 3 0 0 3 3 3 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal zf-C2H2_3 PF13878.1 AIN95251.1 - 3.1e-13 49.0 0.0 7.6e-13 47.7 0.0 1.7 1 0 0 1 1 1 1 zinc-finger of acetyl-transferase ESCO zf-CCCH PF00642.19 AIN95252.1 - 6.1e-08 32.1 8.3 9.5e-05 21.9 0.7 2.9 3 0 0 3 3 3 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) RRM_1 PF00076.17 AIN95252.1 - 3e-05 23.5 0.0 0.00032 20.2 0.0 2.4 2 1 1 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 AIN95252.1 - 0.11 12.4 0.0 0.27 11.0 0.0 1.7 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCCH_2 PF14608.1 AIN95252.1 - 0.45 10.5 5.7 5.9 7.0 1.4 2.7 2 1 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type Aldedh PF00171.17 AIN95253.1 - 2e-103 346.2 0.0 2.5e-103 345.9 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Pkinase PF00069.20 AIN95254.1 - 1.9e-55 187.8 0.0 2.5e-55 187.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AIN95254.1 - 1.3e-29 103.1 0.0 2.5e-29 102.1 0.0 1.4 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.18 AIN95254.1 - 0.005 16.5 1.3 1.9 8.1 0.1 2.8 2 1 1 3 3 3 2 Phosphotransferase enzyme family Kdo PF06293.9 AIN95254.1 - 0.006 15.6 0.0 0.012 14.6 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 AIN95254.1 - 0.017 14.4 0.0 0.029 13.6 0.0 1.5 1 0 0 1 1 1 0 RIO1 family Kinase-like PF14531.1 AIN95254.1 - 0.042 12.8 0.1 0.16 10.9 0.0 2.0 2 1 1 3 3 3 0 Kinase-like AMP-binding PF00501.23 AIN95256.1 - 5.2e-88 295.2 0.2 7.4e-88 294.7 0.1 1.1 1 0 0 1 1 1 1 AMP-binding enzyme DUF1064 PF06356.6 AIN95256.1 - 0.076 13.0 0.2 14 5.7 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1064) Ribosomal_L38e PF01781.13 AIN95258.1 - 8.1e-31 105.5 4.3 9.9e-31 105.3 3.0 1.1 1 0 0 1 1 1 1 Ribosomal L38e protein family DUF2359 PF10151.4 AIN95258.1 - 0.094 11.2 0.1 0.094 11.2 0.0 1.0 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2359) DUF3609 PF12259.3 AIN95259.1 - 0.082 11.5 0.0 0.11 11.1 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3609) Viral_Beta_CD PF04530.7 AIN95259.1 - 0.11 12.6 0.0 0.15 12.2 0.0 1.1 1 0 0 1 1 1 0 Viral Beta C/D like family FYVE PF01363.16 AIN95260.1 - 1.6e-11 43.8 9.4 2.8e-11 43.1 6.5 1.4 1 0 0 1 1 1 1 FYVE zinc finger DUF1631 PF07793.6 AIN95260.1 - 0.0099 14.0 8.9 0.012 13.7 6.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1631) Vps23_core PF09454.5 AIN95260.1 - 0.17 11.5 2.5 0.72 9.4 0.2 2.2 1 1 1 2 2 2 0 Vps23 core domain Elf1 PF05129.8 AIN95260.1 - 0.55 9.9 6.9 1 9.1 4.8 1.4 1 0 0 1 1 1 0 Transcription elongation factor Elf1 like FYVE_2 PF02318.11 AIN95260.1 - 2 8.3 12.0 0.35 10.7 4.9 2.0 2 1 0 2 2 2 0 FYVE-type zinc finger zf-B_box PF00643.19 AIN95260.1 - 2.1 8.2 10.3 1.4 8.8 3.8 2.5 2 0 0 2 2 2 0 B-box zinc finger IBR PF01485.16 AIN95260.1 - 6.9 6.6 10.8 1.6 8.6 4.5 2.0 1 1 1 2 2 2 0 IBR domain CENP-F_leu_zip PF10473.4 AIN95261.1 - 0.0023 17.7 0.4 0.0023 17.7 0.2 4.1 3 1 0 3 3 3 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF3552 PF12072.3 AIN95261.1 - 0.0074 15.5 1.0 0.0074 15.5 0.7 3.5 3 1 0 3 3 3 2 Domain of unknown function (DUF3552) ADIP PF11559.3 AIN95261.1 - 0.89 9.4 22.2 2.1 8.2 2.1 3.6 3 1 0 3 3 3 0 Afadin- and alpha -actinin-Binding APG6 PF04111.7 AIN95261.1 - 6.8 5.6 20.9 1.2 8.1 3.1 3.3 3 0 0 3 3 3 0 Autophagy protein Apg6 DUF4226 PF10774.4 AIN95261.1 - 7.4 6.6 14.2 0.12 12.4 2.0 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4226) DUF4206 PF13901.1 AIN95262.1 - 5.8e-05 22.7 32.1 0.017 14.6 0.0 6.0 5 2 0 5 5 5 4 Domain of unknown function (DUF4206) Reo_sigmaC PF04582.7 AIN95264.1 - 0.089 11.9 20.5 1.4 8.0 0.6 4.8 4 1 0 4 4 4 0 Reovirus sigma C capsid protein DDRGK PF09756.4 AIN95266.1 - 3.5e-24 85.2 24.0 3.6e-16 59.1 0.0 2.3 2 0 0 2 2 2 2 DDRGK domain CAF-1_p150 PF11600.3 AIN95266.1 - 0.0077 15.6 15.0 0.011 15.1 10.4 1.4 1 0 0 1 1 1 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal GAPT PF11770.3 AIN95266.1 - 0.097 12.3 0.0 0.21 11.2 0.0 1.6 1 0 0 1 1 1 0 GRB2-binding adapter (GAPT) Pkinase PF00069.20 AIN95267.1 - 7.3e-36 123.6 1.6 1.6e-27 96.3 0.0 3.8 4 0 0 4 4 4 3 Protein kinase domain Pkinase_Tyr PF07714.12 AIN95267.1 - 2.1e-14 53.2 0.0 1.1e-12 47.6 0.0 2.9 2 1 0 2 2 2 1 Protein tyrosine kinase SR-25 PF10500.4 AIN95267.1 - 0.00014 21.4 6.9 0.00014 21.4 4.8 4.1 5 0 0 5 5 5 1 Nuclear RNA-splicing-associated protein Kinase-like PF14531.1 AIN95267.1 - 0.00034 19.6 0.0 0.00073 18.5 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Pox_ser-thr_kin PF05445.6 AIN95267.1 - 0.56 8.9 0.0 0.85 8.3 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Apt1 PF10351.4 AIN95267.1 - 1 8.1 5.1 1.7 7.3 3.5 1.3 1 0 0 1 1 1 0 Golgi-body localisation protein domain Ctr PF04145.10 AIN95267.1 - 1.3 9.0 2.1 30 4.6 0.0 3.0 3 0 0 3 3 3 0 Ctr copper transporter family Zip PF02535.17 AIN95267.1 - 2.3 7.1 27.5 0.0087 15.1 9.8 2.9 3 0 0 3 3 3 0 ZIP Zinc transporter Grp1_Fun34_YaaH PF01184.14 AIN95270.1 - 1.8e-56 190.8 15.1 2.2e-56 190.4 10.5 1.0 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family MFS_1 PF07690.11 AIN95271.1 - 1e-29 103.3 14.9 1.3e-19 70.1 0.1 2.2 2 0 0 2 2 2 2 Major Facilitator Superfamily T2SM PF04612.7 AIN95271.1 - 0.024 14.4 0.1 0.024 14.4 0.1 2.1 3 0 0 3 3 3 0 Type II secretion system (T2SS), protein M Ribosomal_60s PF00428.14 AIN95273.1 - 3e-21 75.6 13.1 3.6e-21 75.3 9.1 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein Ribosomal_60s PF00428.14 AIN95274.1 - 3e-21 75.6 13.1 3.6e-21 75.3 9.1 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein TLD PF07534.11 AIN95275.1 - 5.1e-15 55.6 0.0 2.4e-14 53.5 0.0 1.9 2 0 0 2 2 2 1 TLD Ank_2 PF12796.2 AIN95278.1 - 1.6e-34 118.0 0.0 1.9e-16 60.1 0.0 3.7 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 AIN95278.1 - 6.6e-31 104.5 3.4 3.2e-07 29.8 0.1 6.0 6 0 0 6 6 6 5 Ankyrin repeat Ank_5 PF13857.1 AIN95278.1 - 4e-28 96.7 3.6 3e-09 36.8 0.0 4.9 2 2 2 4 4 4 4 Ankyrin repeats (many copies) Ank_4 PF13637.1 AIN95278.1 - 6.1e-26 90.3 4.7 3.1e-08 33.8 0.0 5.3 2 2 3 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.1 AIN95278.1 - 1.9e-20 70.8 1.7 0.0043 17.1 0.0 6.4 6 0 0 6 6 6 4 Ankyrin repeat zf-DHHC PF01529.15 AIN95278.1 - 7e-08 32.0 0.1 2e-07 30.5 0.1 1.8 1 1 0 1 1 1 1 DHHC palmitoyltransferase PHO4 PF01384.15 AIN95280.1 - 6.3e-103 343.8 15.5 8e-103 343.5 10.7 1.1 1 0 0 1 1 1 1 Phosphate transporter family DSPc PF00782.15 AIN95281.1 - 0.019 14.5 0.4 0.048 13.2 0.3 1.6 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain SYF2 PF08231.7 AIN95281.1 - 0.66 10.0 4.5 1.5 8.9 3.1 1.5 1 0 0 1 1 1 0 SYF2 splicing factor RRM_1 PF00076.17 AIN95282.1 - 2.1e-12 46.4 0.4 0.00019 21.0 0.0 4.7 4 1 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 AIN95282.1 - 4.1e-07 29.8 0.1 0.21 11.5 0.0 5.3 5 1 0 6 6 6 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 AIN95282.1 - 0.00091 19.0 0.0 1.1 9.1 0.0 3.3 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TruD PF01142.13 AIN95283.1 - 0.02 13.5 0.3 0.04 12.5 0.0 1.6 2 0 0 2 2 2 0 tRNA pseudouridine synthase D (TruD) AAA PF00004.24 AIN95284.1 - 1.2e-44 151.7 0.4 2.1e-44 150.9 0.0 1.6 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_2 PF07724.9 AIN95284.1 - 1.6e-07 31.4 0.0 4.2e-07 30.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.9 AIN95284.1 - 1e-06 28.5 0.2 9e-06 25.4 0.1 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 AIN95284.1 - 1.7e-06 28.1 0.1 0.00042 20.4 0.1 2.4 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 AIN95284.1 - 2.9e-06 27.3 0.0 0.00024 21.1 0.0 2.4 1 1 1 2 2 2 1 AAA ATPase domain RuvB_N PF05496.7 AIN95284.1 - 5e-06 25.7 0.0 1.3e-05 24.4 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_25 PF13481.1 AIN95284.1 - 1.6e-05 24.3 0.7 0.0026 17.1 0.2 2.5 1 1 1 2 2 2 1 AAA domain AAA_19 PF13245.1 AIN95284.1 - 7.6e-05 22.3 0.1 0.00017 21.2 0.1 1.6 1 0 0 1 1 1 1 Part of AAA domain DUF815 PF05673.8 AIN95284.1 - 0.00033 19.6 0.0 0.00072 18.5 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF815) TIP49 PF06068.8 AIN95284.1 - 0.00049 18.9 0.1 0.00098 17.9 0.0 1.4 1 0 0 1 1 1 1 TIP49 C-terminus IstB_IS21 PF01695.12 AIN95284.1 - 0.00053 19.4 0.6 0.0011 18.4 0.0 1.7 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_14 PF13173.1 AIN95284.1 - 0.00065 19.6 0.0 0.0012 18.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 AIN95284.1 - 0.001 19.8 0.7 0.0027 18.5 0.1 2.1 2 1 0 2 2 1 1 AAA domain AAA_18 PF13238.1 AIN95284.1 - 0.0013 19.0 0.2 0.0096 16.2 0.0 2.3 2 1 0 2 2 2 1 AAA domain Mg_chelatase PF01078.16 AIN95284.1 - 0.0014 17.8 0.1 0.0028 16.8 0.0 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.17 AIN95284.1 - 0.0014 18.7 0.0 0.0044 17.1 0.0 1.9 2 0 0 2 2 1 1 RNA helicase Parvo_NS1 PF01057.12 AIN95284.1 - 0.0045 15.8 0.0 0.0087 14.9 0.0 1.4 1 0 0 1 1 1 1 Parvovirus non-structural protein NS1 AAA_24 PF13479.1 AIN95284.1 - 0.0076 15.8 0.0 0.015 14.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 AIN95284.1 - 0.011 14.8 0.1 0.026 13.6 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin KaiC PF06745.8 AIN95284.1 - 0.012 14.7 2.7 0.081 12.0 0.0 2.6 2 1 1 3 3 3 0 KaiC Arch_ATPase PF01637.13 AIN95284.1 - 0.013 15.1 1.2 0.33 10.6 0.0 2.7 2 1 1 3 3 3 0 Archaeal ATPase PhoH PF02562.11 AIN95284.1 - 0.014 14.6 0.1 0.035 13.3 0.1 1.7 1 0 0 1 1 1 0 PhoH-like protein AAA_3 PF07726.6 AIN95284.1 - 0.015 14.8 0.0 0.033 13.7 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 AIN95284.1 - 0.016 14.6 0.1 0.06 12.8 0.0 2.0 1 1 0 1 1 1 0 Sigma-54 interaction domain AAA_28 PF13521.1 AIN95284.1 - 0.017 15.0 0.0 0.038 13.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 AIN95284.1 - 0.023 14.3 0.0 0.21 11.2 0.0 2.1 1 1 1 2 2 2 0 NACHT domain ABC_tran PF00005.22 AIN95284.1 - 0.024 14.9 0.1 0.16 12.2 0.0 2.3 2 0 0 2 2 2 0 ABC transporter AAA_33 PF13671.1 AIN95284.1 - 0.025 14.4 0.1 0.069 13.0 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_11 PF13086.1 AIN95284.1 - 0.053 13.0 0.4 0.5 9.8 0.0 2.3 2 1 0 2 2 2 0 AAA domain UPF0079 PF02367.12 AIN95284.1 - 0.071 12.7 0.1 0.18 11.4 0.0 1.7 2 0 0 2 2 1 0 Uncharacterised P-loop hydrolase UPF0079 NB-ARC PF00931.17 AIN95284.1 - 0.091 11.5 0.4 0.28 9.9 0.0 1.9 2 0 0 2 2 2 0 NB-ARC domain Sigma54_activ_2 PF14532.1 AIN95284.1 - 0.12 12.4 0.0 0.35 10.9 0.0 1.9 1 1 0 1 1 1 0 Sigma-54 interaction domain AAA_23 PF13476.1 AIN95284.1 - 0.64 10.3 3.9 3.4 7.9 0.0 2.3 2 0 0 2 2 2 0 AAA domain FAM176 PF14851.1 AIN95285.1 - 0.022 14.4 0.0 0.022 14.4 0.0 2.9 2 1 2 4 4 4 0 FAM176 family V_ATPase_I PF01496.14 AIN95285.1 - 0.88 7.3 0.0 1.4 6.6 0.0 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family ADH_zinc_N PF00107.21 AIN95287.1 - 1.9e-20 72.7 0.2 4.4e-20 71.5 0.1 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 AIN95287.1 - 1.6e-16 61.3 0.0 4.7e-16 59.8 0.0 1.8 2 1 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 AIN95287.1 - 6.5e-12 45.1 0.1 2.2e-11 43.4 0.0 2.0 2 1 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain CCDC-167 PF15188.1 AIN95288.1 - 1.3 8.9 6.4 2.2 8.3 4.4 1.3 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 167 Helicase_C_2 PF13307.1 AIN95289.1 - 5e-41 140.4 0.0 1.1e-40 139.3 0.0 1.6 1 0 0 1 1 1 1 Helicase C-terminal domain DEAD_2 PF06733.10 AIN95289.1 - 2.2e-20 72.7 0.0 5.7e-07 29.1 0.0 4.3 4 0 0 4 4 4 4 DEAD_2 ResIII PF04851.10 AIN95289.1 - 0.0057 16.5 0.0 6.5 6.5 0.0 3.4 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit Methyltransf_31 PF13847.1 AIN95290.1 - 2.4e-10 40.1 0.0 3.4e-10 39.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 AIN95290.1 - 4.4e-08 33.7 0.0 1.3e-07 32.2 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 AIN95290.1 - 4e-05 23.8 0.0 9.6e-05 22.6 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 AIN95290.1 - 0.00017 22.0 0.0 0.00054 20.3 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 AIN95290.1 - 0.00019 20.8 0.0 0.00039 19.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_26 PF13659.1 AIN95290.1 - 0.00048 20.1 0.0 0.0013 18.7 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain tRNA_U5-meth_tr PF05958.6 AIN95290.1 - 0.00078 18.2 0.0 0.0012 17.6 0.0 1.2 1 0 0 1 1 1 1 tRNA (Uracil-5-)-methyltransferase Methyltransf_9 PF08003.6 AIN95290.1 - 0.0017 17.1 0.0 0.0042 15.8 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF1698) PrmA PF06325.8 AIN95290.1 - 0.0019 17.3 0.0 0.0034 16.5 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_12 PF08242.7 AIN95290.1 - 0.0031 17.9 0.0 0.0082 16.5 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain RNA_Me_trans PF04252.8 AIN95290.1 - 0.025 13.9 0.0 0.042 13.2 0.0 1.3 1 0 0 1 1 1 0 Predicted SAM-dependent RNA methyltransferase Methyltransf_24 PF13578.1 AIN95290.1 - 0.029 15.2 0.1 0.094 13.5 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain FtsJ PF01728.14 AIN95290.1 - 0.045 13.7 0.0 0.13 12.2 0.0 1.6 1 1 0 1 1 1 0 FtsJ-like methyltransferase Methyltransf_23 PF13489.1 AIN95290.1 - 0.045 13.4 0.0 0.088 12.5 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain ArgK PF03308.11 AIN95291.1 - 3.4e-73 245.7 0.0 5e-73 245.1 0.0 1.2 1 0 0 1 1 1 1 ArgK protein cobW PF02492.14 AIN95291.1 - 5.5e-09 35.7 0.1 2.2e-08 33.7 0.0 1.9 1 1 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain CbiA PF01656.18 AIN95291.1 - 0.0052 16.2 0.0 0.01 15.2 0.0 1.5 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_19 PF13245.1 AIN95291.1 - 0.0054 16.4 0.3 0.03 14.0 0.1 2.3 2 0 0 2 2 2 1 Part of AAA domain FtsK_SpoIIIE PF01580.13 AIN95291.1 - 0.018 14.4 0.0 0.036 13.5 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_16 PF13191.1 AIN95291.1 - 0.024 14.6 0.1 0.047 13.6 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain GTP_EFTU PF00009.22 AIN95291.1 - 0.039 13.3 0.1 0.93 8.8 0.0 2.2 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain AAA_29 PF13555.1 AIN95291.1 - 0.045 13.2 0.0 0.097 12.2 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_22 PF13401.1 AIN95291.1 - 0.12 12.5 0.5 1.4 9.0 0.0 2.5 3 0 0 3 3 3 0 AAA domain SMC_N PF02463.14 AIN95291.1 - 0.16 11.1 0.0 0.29 10.3 0.0 1.3 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain CAP_N PF01213.14 AIN95293.1 - 1.2 8.3 6.1 1.9 7.7 4.2 1.2 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal EmrE PF13536.1 AIN95295.1 - 0.0041 17.2 6.1 0.0041 17.2 4.2 3.0 3 0 0 3 3 3 2 Multidrug resistance efflux transporter EmrE PF13536.1 AIN95296.1 - 2.4e-05 24.5 6.5 2.4e-05 24.5 4.5 3.6 3 0 0 3 3 3 2 Multidrug resistance efflux transporter Fer4_3 PF12798.2 AIN95296.1 - 0.37 11.4 4.9 14 6.5 0.1 2.9 2 0 0 2 2 2 0 4Fe-4S binding domain AAA_16 PF13191.1 AIN95297.1 - 0.0039 17.1 0.1 0.0089 16.0 0.1 1.6 1 0 0 1 1 1 1 AAA ATPase domain RecA PF00154.16 AIN95297.1 - 0.011 14.8 0.0 0.017 14.2 0.0 1.1 1 0 0 1 1 1 0 recA bacterial DNA recombination protein AAA_14 PF13173.1 AIN95297.1 - 0.027 14.3 0.0 0.051 13.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.1 AIN95297.1 - 0.037 13.7 0.2 0.037 13.7 0.2 2.0 2 0 0 2 2 2 0 Part of AAA domain AAA_25 PF13481.1 AIN95297.1 - 0.084 12.2 0.1 0.16 11.3 0.1 1.4 1 0 0 1 1 1 0 AAA domain MobB PF03205.9 AIN95297.1 - 0.16 11.7 0.0 0.25 11.0 0.0 1.3 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B HEM4 PF02602.10 AIN95298.1 - 4.7e-56 189.6 0.4 5.5e-56 189.3 0.3 1.0 1 0 0 1 1 1 1 Uroporphyrinogen-III synthase HemD DUF1467 PF07330.7 AIN95298.1 - 0.094 12.5 0.0 0.2 11.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1467) IL13 PF03487.8 AIN95298.1 - 0.12 12.0 0.3 0.92 9.2 0.0 2.4 2 0 0 2 2 2 0 Interleukin-13 DEAD PF00270.24 AIN95299.1 - 1e-20 73.8 0.0 2.6e-19 69.3 0.0 2.8 3 0 0 3 3 3 1 DEAD/DEAH box helicase ResIII PF04851.10 AIN95299.1 - 2.8e-06 27.2 0.0 7.6e-06 25.8 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.26 AIN95299.1 - 0.00014 21.6 0.4 0.00031 20.5 0.3 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Beta_helix PF13229.1 AIN95300.1 - 7.4e-05 22.5 7.3 4.7 6.9 0.0 6.0 5 2 0 5 5 5 3 Right handed beta helix region tRNA_edit PF04073.10 AIN95301.1 - 1.7e-20 73.0 0.1 9.2e-20 70.7 0.1 1.9 1 1 0 1 1 1 1 Aminoacyl-tRNA editing domain Serglycin PF04360.7 AIN95302.1 - 0.017 14.8 0.2 0.038 13.7 0.2 1.5 1 0 0 1 1 1 0 Serglycin COX17 PF05051.8 AIN95304.1 - 2e-19 69.3 7.5 2.6e-19 68.9 5.2 1.1 1 0 0 1 1 1 1 Cytochrome C oxidase copper chaperone (COX17) TatD_DNase PF01026.16 AIN95305.1 - 5.9e-50 169.8 0.6 1e-49 169.0 0.4 1.4 1 0 0 1 1 1 1 TatD related DNase LRR_4 PF12799.2 AIN95307.1 - 1.5e-12 46.8 7.0 0.00017 21.1 0.0 3.9 3 1 0 3 3 3 3 Leucine Rich repeats (2 copies) Ubiquitin_2 PF14560.1 AIN95307.1 - 1.6e-09 37.8 0.0 3e-09 37.0 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-like domain LRR_8 PF13855.1 AIN95307.1 - 4.5e-09 35.9 6.4 0.0016 18.1 1.3 3.6 3 0 0 3 3 3 3 Leucine rich repeat LRR_9 PF14580.1 AIN95307.1 - 2.5e-06 27.1 0.8 0.047 13.2 0.0 3.4 3 0 0 3 3 3 2 Leucine-rich repeat LRR_6 PF13516.1 AIN95307.1 - 9.6e-05 22.0 6.0 9.9 6.5 0.0 5.7 6 0 0 6 6 6 1 Leucine Rich repeat LRR_1 PF00560.28 AIN95307.1 - 0.00064 19.3 9.5 12 6.4 0.1 5.8 6 1 0 6 6 6 1 Leucine Rich Repeat ubiquitin PF00240.18 AIN95307.1 - 0.0013 18.1 0.2 0.017 14.4 0.1 2.4 1 1 0 1 1 1 1 Ubiquitin family LRR_7 PF13504.1 AIN95307.1 - 0.0019 18.0 17.1 12 6.5 0.1 6.5 7 0 0 7 7 7 1 Leucine rich repeat Pkinase PF00069.20 AIN95308.1 - 1.8e-53 181.3 0.0 6e-32 110.8 0.0 3.3 3 0 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.12 AIN95308.1 - 5.3e-23 81.4 0.0 4.5e-11 42.3 0.0 3.0 2 1 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 AIN95308.1 - 0.0043 16.0 0.0 0.0084 15.0 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Pox_ser-thr_kin PF05445.6 AIN95308.1 - 3.6 6.2 0.0 5.2 5.7 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase RNA_pol_Rpb4 PF03874.11 AIN95309.1 - 0.083 12.9 0.0 0.52 10.3 0.0 2.2 3 0 0 3 3 3 0 RNA polymerase Rpb4 6PF2K PF01591.13 AIN95310.1 - 1.4e-62 210.6 0.0 2.1e-62 210.1 0.0 1.2 1 0 0 1 1 1 1 6-phosphofructo-2-kinase Ank_2 PF12796.2 AIN95310.1 - 4.9e-15 55.6 0.2 1.1e-14 54.4 0.2 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 AIN95310.1 - 9.9e-12 44.0 0.7 7.4e-07 28.6 0.1 3.1 2 0 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.1 AIN95310.1 - 2.5e-11 43.7 2.6 3e-09 37.1 0.1 2.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.1 AIN95310.1 - 3.7e-08 33.3 3.7 8e-07 29.1 0.5 2.7 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 AIN95310.1 - 1.7e-07 30.7 0.1 0.015 15.4 0.0 3.0 2 0 0 2 2 2 2 Ankyrin repeat AAA_33 PF13671.1 AIN95310.1 - 7.7e-07 29.0 0.0 2.5e-06 27.4 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 AIN95310.1 - 0.013 16.2 0.0 0.026 15.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain Serglycin PF04360.7 AIN95310.1 - 0.1 12.3 1.9 0.22 11.2 0.3 2.3 2 0 0 2 2 2 0 Serglycin USP7_C2 PF14533.1 AIN95310.1 - 1.5 8.2 0.0 2.5 7.4 0.0 1.2 1 0 0 1 1 1 0 Ubiquitin-specific protease C-terminal zf-MYND PF01753.13 AIN95314.1 - 0.00051 19.8 7.1 0.0011 18.8 4.9 1.5 1 0 0 1 1 1 1 MYND finger LRR_4 PF12799.2 AIN95317.1 - 6.4e-09 35.2 7.4 0.026 14.1 0.0 5.1 2 1 2 5 5 5 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 AIN95317.1 - 4.9e-06 26.1 14.0 0.0002 21.0 0.6 3.4 3 0 0 3 3 3 2 Leucine rich repeat LRR_6 PF13516.1 AIN95317.1 - 0.00023 20.9 2.9 14 6.1 0.0 6.2 6 0 0 6 6 6 1 Leucine Rich repeat LRR_1 PF00560.28 AIN95317.1 - 0.0079 16.0 9.9 5.9 7.3 0.4 6.4 6 1 1 7 7 7 1 Leucine Rich Repeat NIF PF03031.13 AIN95319.1 - 4.3e-27 94.7 0.0 1.7e-19 70.0 0.0 2.4 2 0 0 2 2 2 2 NLI interacting factor-like phosphatase Brix PF04427.13 AIN95320.1 - 5.3e-44 150.1 0.1 8.1e-44 149.5 0.0 1.3 1 0 0 1 1 1 1 Brix domain SLX9 PF15341.1 AIN95320.1 - 5 7.5 14.2 1.8e+02 2.5 9.8 2.8 2 1 0 2 2 2 0 Ribosome biogenesis protein SLX9 Pyrophosphatase PF00719.14 AIN95321.1 - 1.8e-43 147.6 0.0 2.3e-43 147.3 0.0 1.1 1 0 0 1 1 1 1 Inorganic pyrophosphatase Got1 PF04178.7 AIN95322.1 - 1.8e-27 95.8 20.5 2.5e-27 95.3 14.2 1.2 1 0 0 1 1 1 1 Got1/Sft2-like family Peptidase_U4 PF03419.8 AIN95322.1 - 7.8 5.4 10.3 11 4.9 7.1 1.3 1 0 0 1 1 1 0 Sporulation factor SpoIIGA Amidohydro_3 PF07969.6 AIN95323.1 - 2.2e-53 181.9 2.3 1.9e-27 96.5 3.0 2.2 1 1 1 2 2 2 2 Amidohydrolase family Amidohydro_1 PF01979.15 AIN95323.1 - 9.5e-11 41.9 1.1 9.6e-07 28.7 0.0 2.9 2 1 0 2 2 2 2 Amidohydrolase family Amidohydro_5 PF13594.1 AIN95323.1 - 3.1e-07 30.1 0.0 1.2e-06 28.1 0.0 2.1 1 1 0 1 1 1 1 Amidohydrolase Cu-oxidase_2 PF07731.9 AIN95325.1 - 8.6e-19 67.4 1.1 8.6e-19 67.4 0.8 2.9 2 1 0 2 2 2 1 Multicopper oxidase Cu-oxidase_3 PF07732.10 AIN95325.1 - 8.4e-11 41.6 4.7 2.4e-06 27.2 0.5 4.0 3 1 1 4 4 4 3 Multicopper oxidase MORN PF02493.15 AIN95327.1 - 5.2e-23 79.3 38.6 6.5e-06 25.5 0.9 7.5 8 1 0 8 8 8 6 MORN repeat EIF_2_alpha PF07541.7 AIN95328.1 - 1.3e-24 86.1 0.0 4e-23 81.3 0.0 2.2 1 1 1 2 2 2 1 Eukaryotic translation initiation factor 2 alpha subunit S1 PF00575.18 AIN95328.1 - 8.8e-11 41.7 0.3 1.8e-10 40.7 0.2 1.6 1 0 0 1 1 1 1 S1 RNA binding domain EXOSC1 PF10447.4 AIN95328.1 - 0.0028 17.5 0.3 0.0058 16.5 0.2 1.6 1 0 0 1 1 1 1 Exosome component EXOSC1/CSL4 E1-E2_ATPase PF00122.15 AIN95329.1 - 8.1e-65 218.0 0.9 8.1e-65 218.0 0.6 2.3 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 AIN95329.1 - 9.5e-43 145.8 6.2 9.5e-43 145.8 4.3 2.2 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 AIN95329.1 - 4e-30 105.8 0.0 6.2e-29 101.9 0.0 2.7 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 AIN95329.1 - 2.3e-17 62.7 0.1 6.4e-17 61.3 0.1 1.8 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Cation_ATPase_N PF00690.21 AIN95329.1 - 2.5e-14 52.4 0.9 4.2e-14 51.7 0.0 1.9 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus HAD PF12710.2 AIN95329.1 - 6.5e-14 52.5 0.0 2.4e-13 50.6 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 AIN95329.1 - 1.7e-07 31.1 1.4 5.5e-06 26.1 0.6 2.4 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase PDEase_I PF00233.14 AIN95330.1 - 1.5e-11 44.4 2.3 1.6e-11 44.4 0.8 1.6 2 0 0 2 2 2 1 3'5'-cyclic nucleotide phosphodiesterase Spore-coat_CotD PF11122.3 AIN95334.1 - 0.68 10.2 4.4 0.23 11.7 0.2 2.3 3 0 0 3 3 3 0 Inner spore coat protein D Topo_C_assoc PF14370.1 AIN95335.1 - 7.5e-28 95.9 0.2 1.1e-27 95.4 0.1 1.3 1 0 0 1 1 1 1 C-terminal topoisomerase domain RAP1 PF07218.6 AIN95335.1 - 0.0052 14.9 9.8 0.0058 14.8 6.8 1.1 1 0 0 1 1 1 1 Rhoptry-associated protein 1 (RAP-1) Macoilin PF09726.4 AIN95335.1 - 0.075 11.3 7.4 0.084 11.1 5.1 1.1 1 0 0 1 1 1 0 Transmembrane protein AF-4 PF05110.8 AIN95335.1 - 0.097 10.5 20.6 0.13 10.1 14.2 1.3 1 0 0 1 1 1 0 AF-4 proto-oncoprotein FRQ PF09421.5 AIN95335.1 - 0.27 8.9 14.6 0.36 8.5 10.1 1.1 1 0 0 1 1 1 0 Frequency clock protein CAF-1_p150 PF11600.3 AIN95335.1 - 1 8.7 9.4 1.5 8.1 6.5 1.3 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Herpes_LMP2 PF07415.6 AIN95335.1 - 3 6.3 4.9 4.1 5.8 3.4 1.1 1 0 0 1 1 1 0 Gammaherpesvirus latent membrane protein (LMP2) protein Polyoma_lg_T_C PF06431.6 AIN95335.1 - 8.7 4.8 7.9 21 3.5 0.0 2.1 1 1 1 2 2 2 0 Polyomavirus large T antigen C-terminus Methyltransf_31 PF13847.1 AIN95336.1 - 0.00052 19.6 0.0 0.00073 19.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 AIN95336.1 - 0.00096 19.7 0.0 0.0019 18.7 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 AIN95336.1 - 0.005 17.1 0.0 0.0088 16.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 AIN95336.1 - 0.016 15.6 0.0 0.025 15.0 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain DASH_Dam1 PF08653.5 AIN95337.1 - 0.025 14.3 0.2 0.04 13.6 0.2 1.3 1 0 0 1 1 1 0 DASH complex subunit Dam1 CorA PF01544.13 AIN95337.1 - 0.03 13.3 0.8 0.035 13.1 0.6 1.1 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein IZUMO PF15005.1 AIN95339.1 - 0.01 15.9 0.3 0.024 14.6 0.1 1.7 1 1 0 1 1 1 0 Izumo sperm-egg fusion DUF3584 PF12128.3 AIN95339.1 - 0.027 11.8 10.2 0.038 11.3 7.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DAHP_synth_1 PF00793.15 AIN95339.1 - 0.035 12.7 0.1 0.057 12.0 0.0 1.2 1 0 0 1 1 1 0 DAHP synthetase I family BRE1 PF08647.6 AIN95339.1 - 0.12 12.4 6.7 2.1 8.3 1.6 2.5 2 0 0 2 2 2 0 BRE1 E3 ubiquitin ligase ApoLp-III PF07464.6 AIN95339.1 - 0.48 10.4 7.5 0.79 9.7 5.2 1.2 1 0 0 1 1 1 0 Apolipophorin-III precursor (apoLp-III) CP12 PF02672.10 AIN95339.1 - 1.4 9.4 0.0 1.4 9.4 0.0 3.2 3 0 0 3 3 3 0 CP12 domain ERM PF00769.14 AIN95340.1 - 0.089 12.3 4.5 0.039 13.4 1.2 1.9 2 1 0 2 2 2 0 Ezrin/radixin/moesin family HALZ PF02183.13 AIN95343.1 - 0.074 12.7 0.4 0.2 11.3 0.1 1.9 2 0 0 2 2 2 0 Homeobox associated leucine zipper VSP PF03302.8 AIN95345.1 - 7.2e-06 24.8 51.3 0.00014 20.6 8.7 4.2 1 1 2 3 3 3 3 Giardia variant-specific surface protein Shisa PF13908.1 AIN95347.1 - 0.00082 19.5 2.2 0.0016 18.6 1.5 1.5 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator T2SM PF04612.7 AIN95347.1 - 0.05 13.3 0.1 0.073 12.8 0.1 1.2 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein M GRAM PF02893.15 AIN95348.1 - 9.8e-05 21.8 0.0 0.00024 20.5 0.0 1.7 1 1 0 1 1 1 1 GRAM domain PseudoU_synth_2 PF00849.17 AIN95349.1 - 3.6e-38 130.9 0.0 6.1e-38 130.2 0.0 1.4 1 0 0 1 1 1 1 RNA pseudouridylate synthase TPR_11 PF13414.1 AIN95350.1 - 0.00022 20.8 10.6 0.18 11.4 0.5 3.6 3 0 0 3 3 3 3 TPR repeat TPR_2 PF07719.12 AIN95350.1 - 0.0053 16.5 3.8 5.4 7.1 0.0 4.0 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.23 AIN95350.1 - 0.0099 15.4 2.5 3.7 7.3 0.0 3.5 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_10 PF13374.1 AIN95350.1 - 0.018 14.9 0.2 0.07 13.0 0.1 2.1 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_12 PF13424.1 AIN95350.1 - 1.5 8.8 7.3 0.66 9.9 0.1 3.1 2 1 1 3 3 3 0 Tetratricopeptide repeat MRP-L47 PF06984.8 AIN95351.1 - 1.8e-28 98.2 0.4 9e-28 96.0 0.1 2.2 2 0 0 2 2 2 1 Mitochondrial 39-S ribosomal protein L47 (MRP-L47) A_deaminase PF00962.17 AIN95352.1 - 2e-80 270.2 0.2 2.2e-56 191.1 0.0 3.0 3 0 0 3 3 3 2 Adenosine/AMP deaminase ADH_N PF08240.7 AIN95353.1 - 8.2e-08 31.9 0.7 1.6e-07 31.0 0.5 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 AIN95353.1 - 9.4e-05 21.9 0.0 0.0002 20.8 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase DUF4164 PF13747.1 AIN95354.1 - 0.006 16.6 0.5 0.012 15.7 0.0 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4164) Glyco_hydro_32N PF00251.15 AIN95355.1 - 4.7e-58 196.9 6.2 6.6e-58 196.4 4.3 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 N-terminal domain Glyco_hydro_32C PF08244.7 AIN95355.1 - 2.5e-06 27.7 0.0 0.0015 18.8 0.0 2.8 3 0 0 3 3 3 2 Glycosyl hydrolases family 32 C terminal PAN_1 PF00024.21 AIN95355.1 - 4.3e-06 26.3 1.8 9.1e-06 25.3 1.2 1.5 1 0 0 1 1 1 1 PAN domain PAN_4 PF14295.1 AIN95355.1 - 0.016 14.9 1.3 0.045 13.4 0.9 1.8 1 0 0 1 1 1 0 PAN domain DUF2618 PF10940.3 AIN95355.1 - 0.12 12.1 0.1 0.12 12.1 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2618) RNB PF00773.14 AIN95356.1 - 1.5e-55 188.8 0.0 2.8e-54 184.5 0.0 2.1 2 0 0 2 2 2 2 RNB domain Arf PF00025.16 AIN95357.1 - 1.2e-53 180.9 0.0 1.3e-53 180.7 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.17 AIN95357.1 - 9.5e-15 54.3 0.0 1e-14 54.2 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 AIN95357.1 - 1.7e-12 47.8 0.0 2.4e-12 47.3 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein SRPRB PF09439.5 AIN95357.1 - 1e-11 44.4 0.0 1.2e-11 44.1 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.7 AIN95357.1 - 2.8e-10 39.7 0.0 3.4e-10 39.4 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region G-alpha PF00503.15 AIN95357.1 - 3.4e-08 32.5 0.6 1.2e-05 24.2 0.0 2.2 1 1 1 2 2 2 2 G-protein alpha subunit MMR_HSR1 PF01926.18 AIN95357.1 - 1.8e-06 27.9 0.0 2.4e-06 27.4 0.0 1.1 1 0 0 1 1 1 1 50S ribosome-binding GTPase ABC_tran PF00005.22 AIN95357.1 - 0.0039 17.5 0.0 0.014 15.7 0.0 1.7 1 1 0 1 1 1 1 ABC transporter GTP_EFTU PF00009.22 AIN95357.1 - 0.0061 16.0 0.0 0.039 13.3 0.0 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.1 AIN95357.1 - 0.026 14.6 0.4 0.09 12.9 0.3 1.9 1 1 0 1 1 1 0 AAA domain Urocanase PF01175.13 AIN95357.1 - 0.091 10.7 0.0 0.12 10.3 0.0 1.1 1 0 0 1 1 1 0 Urocanase zf-MYND PF01753.13 AIN95358.1 - 0.00087 19.1 9.5 0.003 17.3 6.6 2.0 1 0 0 1 1 1 1 MYND finger PhyH PF05721.8 AIN95360.1 - 1.6e-43 149.2 0.0 2.2e-43 148.7 0.0 1.1 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) DUF3243 PF11588.3 AIN95360.1 - 0.033 14.1 0.2 0.087 12.8 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3243) Shisa PF13908.1 AIN95361.1 - 0.00028 21.1 0.2 0.00073 19.7 0.0 1.7 2 0 0 2 2 2 1 Wnt and FGF inhibitory regulator CCSMST1 PF15013.1 AIN95361.1 - 0.0083 16.0 0.1 0.019 14.8 0.1 1.6 1 0 0 1 1 1 1 CCSMST1 family SieB PF14163.1 AIN95361.1 - 0.012 15.1 0.1 0.047 13.2 0.0 2.0 2 0 0 2 2 2 0 Superinfection exclusion protein B DUF3357 PF11837.3 AIN95361.1 - 0.025 14.3 0.0 0.073 12.9 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF3357) CcoS PF03597.10 AIN95361.1 - 0.028 13.8 0.0 0.028 13.8 0.0 1.7 2 0 0 2 2 2 0 Cytochrome oxidase maturation protein cbb3-type EphA2_TM PF14575.1 AIN95361.1 - 0.077 13.3 0.9 0.17 12.2 0.0 2.0 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Epiglycanin_C PF14654.1 AIN95361.1 - 0.082 12.9 0.0 0.19 11.7 0.0 1.6 1 0 0 1 1 1 0 Mucin, catalytic, TM and cytoplasmic tail region IncA PF04156.9 AIN95361.1 - 0.28 10.7 0.1 0.28 10.7 0.0 1.9 2 0 0 2 2 2 0 IncA protein DcuC PF03606.10 AIN95361.1 - 0.33 9.1 2.4 0.35 9.0 0.0 1.9 2 0 0 2 2 2 0 C4-dicarboxylate anaerobic carrier Corona_S2 PF01601.11 AIN95361.1 - 3.4 5.6 6.8 0.45 8.5 1.8 1.5 2 0 0 2 2 2 0 Coronavirus S2 glycoprotein APC10 PF03256.11 AIN95362.1 - 5.5e-58 195.7 0.0 1.8e-51 174.5 0.0 2.2 2 0 0 2 2 2 2 Anaphase-promoting complex, subunit 10 (APC10) TPR_1 PF00515.23 AIN95364.1 - 7.5e-10 37.9 4.2 0.0003 20.2 0.0 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.12 AIN95364.1 - 2.1e-08 33.4 11.0 2.5e-05 23.8 0.2 4.2 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_11 PF13414.1 AIN95364.1 - 4.8e-08 32.5 12.5 0.00085 18.9 0.7 4.0 4 1 0 4 4 4 2 TPR repeat TPR_8 PF13181.1 AIN95364.1 - 7.7e-07 28.4 2.1 0.0012 18.4 0.0 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.1 AIN95364.1 - 1.2e-06 28.6 1.5 0.00082 19.8 0.0 5.8 5 2 1 6 6 6 2 Tetratricopeptide repeat TPR_12 PF13424.1 AIN95364.1 - 0.0016 18.3 14.4 0.15 12.0 0.4 4.9 2 1 3 5 5 5 3 Tetratricopeptide repeat TPR_9 PF13371.1 AIN95364.1 - 0.016 15.0 9.2 1.6 8.6 0.2 4.3 2 1 1 4 4 4 0 Tetratricopeptide repeat SNAP PF14938.1 AIN95364.1 - 0.018 14.2 5.0 0.048 12.8 0.3 2.6 3 0 0 3 3 3 0 Soluble NSF attachment protein, SNAP TPR_16 PF13432.1 AIN95364.1 - 0.091 13.4 24.8 0.72 10.6 0.3 5.5 3 1 3 6 6 6 0 Tetratricopeptide repeat TPR_17 PF13431.1 AIN95364.1 - 0.15 12.3 5.6 30 5.1 0.0 5.4 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_7 PF13176.1 AIN95364.1 - 0.17 11.7 0.1 0.17 11.7 0.0 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.1 AIN95364.1 - 0.25 11.8 5.4 4.9 7.8 0.0 3.7 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_19 PF14559.1 AIN95364.1 - 0.26 11.6 0.2 0.26 11.6 0.1 4.6 4 2 0 4 4 4 0 Tetratricopeptide repeat Pkinase PF00069.20 AIN95365.1 - 7.7e-43 146.5 0.0 5.3e-36 124.0 0.0 4.2 2 2 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 AIN95365.1 - 7.4e-33 113.7 0.0 1.3e-16 60.4 0.0 4.2 4 0 0 4 4 4 4 Protein tyrosine kinase APH PF01636.18 AIN95365.1 - 0.023 14.4 0.5 0.45 10.2 0.0 2.6 2 0 0 2 2 2 0 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.6 AIN95365.1 - 0.87 8.3 0.0 1.3 7.7 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Peptidase_C2 PF00648.16 AIN95366.1 - 1e-48 165.8 0.0 1.5e-48 165.3 0.0 1.1 1 0 0 1 1 1 1 Calpain family cysteine protease DUF1935 PF09149.5 AIN95366.1 - 1.2e-34 118.4 0.0 2.8e-34 117.2 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1935) Peptidase_M16_C PF05193.16 AIN95366.1 - 0.16 11.6 0.5 22 4.6 0.2 2.4 2 0 0 2 2 2 0 Peptidase M16 inactive domain Lyase_1 PF00206.15 AIN95367.1 - 1.5e-48 165.5 0.0 2.1e-48 165.1 0.0 1.2 1 0 0 1 1 1 1 Lyase ASL_C PF08328.6 AIN95367.1 - 1e-45 154.2 0.0 1.8e-45 153.4 0.0 1.5 1 0 0 1 1 1 1 Adenylosuccinate lyase C-terminal N_Asn_amidohyd PF14736.1 AIN95368.1 - 0.028 13.2 0.1 0.41 9.4 0.0 2.9 4 0 0 4 4 4 0 Protein N-terminal asparagine amidohydrolase Ribosomal_L5_C PF00673.16 AIN95369.1 - 6.5e-22 77.0 0.0 1.1e-21 76.3 0.0 1.4 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.14 AIN95369.1 - 1.5e-16 59.9 0.4 5.5e-16 58.0 0.0 2.0 2 0 0 2 2 2 1 Ribosomal protein L5 Arf PF00025.16 AIN95370.1 - 2.2e-60 202.8 0.0 2.5e-60 202.6 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 AIN95370.1 - 1.4e-13 50.5 0.0 1.7e-13 50.2 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.17 AIN95370.1 - 6.4e-12 45.1 0.0 7.8e-12 44.8 0.0 1.1 1 0 0 1 1 1 1 Ras family G-alpha PF00503.15 AIN95370.1 - 1.7e-11 43.4 0.4 1.6e-09 36.9 0.0 2.4 1 1 1 2 2 2 2 G-protein alpha subunit Miro PF08477.8 AIN95370.1 - 5.2e-08 33.3 0.0 6.8e-08 33.0 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Gtr1_RagA PF04670.7 AIN95370.1 - 7.2e-07 28.5 0.0 8.6e-07 28.3 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region 6PF2K PF01591.13 AIN95370.1 - 7.1e-05 21.9 0.0 9.8e-05 21.5 0.0 1.2 1 0 0 1 1 1 1 6-phosphofructo-2-kinase MMR_HSR1 PF01926.18 AIN95370.1 - 0.00021 21.2 0.0 0.00029 20.7 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 AIN95370.1 - 0.0066 15.9 0.0 0.28 10.5 0.0 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain NACHT PF05729.7 AIN95370.1 - 0.0093 15.6 0.2 0.089 12.4 0.2 2.0 1 1 0 1 1 1 1 NACHT domain AAA_33 PF13671.1 AIN95370.1 - 0.022 14.6 0.0 0.028 14.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.7 AIN95370.1 - 0.027 13.5 0.0 0.041 12.9 0.0 1.2 1 0 0 1 1 1 0 Zeta toxin AAA_18 PF13238.1 AIN95370.1 - 0.11 12.7 0.0 0.16 12.2 0.0 1.6 1 1 0 1 1 1 0 AAA domain PAP_assoc PF03828.14 AIN95372.1 - 2.8e-05 23.9 0.1 5e-05 23.1 0.0 1.5 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.18 AIN95372.1 - 7.8e-05 22.9 0.0 0.00016 21.9 0.0 1.4 1 0 0 1 1 1 1 Nucleotidyltransferase domain Tmemb_cc2 PF10267.4 AIN95373.1 - 5.5 5.4 6.2 9.4 4.7 4.3 1.3 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein Ank_2 PF12796.2 AIN95374.1 - 1.5e-26 92.4 0.6 8.2e-15 54.9 0.0 4.4 3 1 1 4 4 4 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 AIN95374.1 - 2e-24 85.5 1.3 1.8e-08 34.6 0.0 5.8 4 1 1 5 5 5 5 Ankyrin repeats (many copies) Ank PF00023.25 AIN95374.1 - 4.4e-20 70.4 23.0 2.7e-10 39.5 0.0 6.4 7 1 0 7 7 7 3 Ankyrin repeat Ank_5 PF13857.1 AIN95374.1 - 1.6e-19 69.4 9.3 7.2e-11 41.9 0.1 5.6 5 0 0 5 5 5 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 AIN95374.1 - 4.1e-18 63.6 5.0 7.9e-06 25.6 0.0 6.4 6 0 0 6 6 6 4 Ankyrin repeat zf-DHHC PF01529.15 AIN95374.1 - 1.3e-14 53.9 1.2 1.3e-14 53.9 0.8 2.3 2 0 0 2 2 2 1 DHHC palmitoyltransferase UCR_Fe-S_N PF10399.4 AIN95375.1 - 0.089 11.9 4.6 0.36 10.0 3.2 2.1 1 0 0 1 1 1 0 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal TPR_19 PF14559.1 AIN95376.1 - 1.8e-34 117.9 56.8 1.4e-06 28.5 0.9 15.9 12 3 5 17 17 16 11 Tetratricopeptide repeat TPR_11 PF13414.1 AIN95376.1 - 2.1e-33 113.7 36.6 6.5e-07 28.9 0.0 13.4 11 3 3 15 15 15 8 TPR repeat TPR_16 PF13432.1 AIN95376.1 - 3.3e-28 97.7 77.8 4.9e-09 36.6 2.8 16.4 16 4 2 19 19 16 7 Tetratricopeptide repeat TPR_2 PF07719.12 AIN95376.1 - 4.5e-28 94.8 40.3 0.0006 19.5 0.2 18.3 22 0 0 22 22 19 7 Tetratricopeptide repeat TPR_14 PF13428.1 AIN95376.1 - 4.3e-26 89.0 83.1 7.9e-05 22.9 0.0 21.8 12 6 12 24 24 23 7 Tetratricopeptide repeat TPR_1 PF00515.23 AIN95376.1 - 9.6e-23 78.8 23.5 0.0002 20.7 0.5 13.0 14 0 0 14 14 14 5 Tetratricopeptide repeat TPR_8 PF13181.1 AIN95376.1 - 3.5e-20 70.2 1.6 0.0072 16.0 0.0 10.4 11 0 0 11 11 10 4 Tetratricopeptide repeat TPR_7 PF13176.1 AIN95376.1 - 2.9e-16 57.8 27.3 0.006 16.2 0.0 13.1 15 0 0 15 15 12 5 Tetratricopeptide repeat TPR_12 PF13424.1 AIN95376.1 - 2.3e-15 56.2 71.5 0.0013 18.6 0.0 17.4 15 5 7 22 22 22 6 Tetratricopeptide repeat TPR_17 PF13431.1 AIN95376.1 - 7.7e-11 41.3 16.2 1 9.6 0.0 13.1 15 0 0 15 15 14 1 Tetratricopeptide repeat TPR_4 PF07721.9 AIN95376.1 - 2.3e-08 33.6 40.4 0.038 14.4 0.0 13.1 12 0 0 12 12 11 2 Tetratricopeptide repeat NARP1 PF12569.3 AIN95376.1 - 3.8e-06 25.9 6.4 0.33 9.6 0.1 5.9 6 2 1 7 7 7 2 NMDA receptor-regulated protein 1 TPR_6 PF13174.1 AIN95376.1 - 0.00011 22.4 68.5 0.35 11.4 0.0 18.6 23 0 0 23 23 18 2 Tetratricopeptide repeat PPR PF01535.15 AIN95376.1 - 0.019 14.8 2.1 2.2 8.4 0.0 5.1 5 0 0 5 5 5 0 PPR repeat TPR_10 PF13374.1 AIN95376.1 - 0.12 12.3 0.1 0.12 12.3 0.1 11.4 13 0 0 13 13 12 0 Tetratricopeptide repeat MIT PF04212.13 AIN95376.1 - 0.42 10.5 15.3 11 5.9 0.1 5.6 6 0 0 6 6 5 0 MIT (microtubule interacting and transport) domain ChAPs PF09295.5 AIN95376.1 - 0.81 8.3 6.5 0.35 9.5 0.1 2.8 4 0 0 4 4 4 0 ChAPs (Chs5p-Arf1p-binding proteins) TPR_9 PF13371.1 AIN95376.1 - 2 8.3 39.0 0.42 10.5 0.7 8.7 7 2 2 9 9 8 0 Tetratricopeptide repeat Y_phosphatase2 PF03162.8 AIN95377.1 - 8.7e-52 174.8 0.0 1.1e-51 174.4 0.0 1.1 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3 PF13350.1 AIN95377.1 - 1e-08 35.5 0.0 2.8e-08 34.1 0.0 1.6 1 1 1 2 2 2 1 Tyrosine phosphatase family Y_phosphatase PF00102.22 AIN95377.1 - 0.0054 16.1 0.0 0.0067 15.7 0.0 1.1 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.15 AIN95377.1 - 0.027 14.0 0.0 0.038 13.5 0.0 1.2 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.1 AIN95377.1 - 0.042 13.9 0.0 0.063 13.3 0.0 1.3 1 0 0 1 1 1 0 Inositol hexakisphosphate DENN PF02141.16 AIN95378.1 - 9.5e-09 35.2 0.2 3e-08 33.6 0.2 1.8 1 0 0 1 1 1 1 DENN (AEX-3) domain Spermine_synth PF01564.12 AIN95379.1 - 8.2e-67 224.7 0.0 1e-66 224.3 0.0 1.0 1 0 0 1 1 1 1 Spermine/spermidine synthase Methyltransf_12 PF08242.7 AIN95379.1 - 0.006 17.0 0.0 0.06 13.8 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 AIN95379.1 - 0.0099 15.9 0.0 0.021 14.8 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 AIN95379.1 - 0.023 15.2 0.0 0.041 14.4 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_23 PF13489.1 AIN95379.1 - 0.035 13.8 0.0 0.071 12.8 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.7 AIN95379.1 - 0.078 13.4 0.0 0.28 11.7 0.0 1.9 1 1 0 1 1 1 0 Methyltransferase domain Neur_chan_memb PF02932.11 AIN95380.1 - 0.00074 19.4 0.1 0.0011 18.9 0.1 1.3 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region Rootletin PF15035.1 AIN95380.1 - 0.002 18.1 1.7 0.0025 17.8 1.2 1.1 1 0 0 1 1 1 1 Ciliary rootlet component, centrosome cohesion DUF2207 PF09972.4 AIN95380.1 - 0.02 13.4 0.0 0.033 12.8 0.0 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Cwf_Cwc_15 PF04889.7 AIN95381.1 - 0.00056 19.7 10.7 0.00062 19.5 7.4 1.2 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein DUF755 PF05501.6 AIN95381.1 - 0.002 18.1 14.2 0.002 18.1 9.9 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF755) DUF1168 PF06658.7 AIN95381.1 - 0.0044 16.5 14.1 0.0052 16.2 9.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1168) DUF3482 PF11981.3 AIN95381.1 - 0.09 11.9 9.6 0.12 11.5 6.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3482) DUF3513 PF12026.3 AIN95381.1 - 0.38 10.2 7.2 0.55 9.7 5.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3513) DUF4603 PF15376.1 AIN95381.1 - 0.47 7.5 10.9 0.58 7.2 7.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4603) DUF572 PF04502.8 AIN95381.1 - 0.56 9.3 11.6 0.58 9.3 8.1 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) BTV_NS2 PF04514.7 AIN95381.1 - 1.4 7.7 6.9 1.6 7.5 4.8 1.1 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 U1snRNP70_N PF12220.3 AIN95381.1 - 4.3 7.7 11.0 5 7.5 6.0 2.1 1 1 1 2 2 2 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal MFMR PF07777.6 AIN95381.1 - 4.3 7.2 8.6 6.4 6.6 6.0 1.3 1 0 0 1 1 1 0 G-box binding protein MFMR FAM60A PF15396.1 AIN95381.1 - 6.5 6.4 13.1 7.9 6.1 8.8 1.4 1 1 0 1 1 1 0 Protein Family FAM60A HCNGP PF07818.8 AIN95384.1 - 0.014 15.4 0.2 0.021 14.8 0.1 1.3 1 0 0 1 1 1 0 HCNGP-like protein TFIID-18kDa PF02269.11 AIN95384.1 - 0.043 13.6 0.5 0.08 12.7 0.4 1.5 1 0 0 1 1 1 0 Transcription initiation factor IID, 18kD subunit BatD PF13584.1 AIN95384.1 - 0.046 12.3 0.0 0.066 11.7 0.0 1.2 1 0 0 1 1 1 0 Oxygen tolerance DUF600 PF04634.7 AIN95384.1 - 0.055 13.4 1.3 0.099 12.6 0.5 1.7 1 1 1 2 2 2 0 Protein of unknown function, DUF600 DUF4234 PF14018.1 AIN95384.1 - 0.088 12.5 1.1 0.18 11.5 0.6 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4234) zf-C3HC4_3 PF13920.1 AIN95385.1 - 6.6e-09 35.3 9.8 1.4e-08 34.3 6.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 AIN95385.1 - 2.3e-07 30.3 10.0 4.5e-07 29.4 6.9 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 AIN95385.1 - 4.5e-06 26.5 12.9 8.6e-06 25.6 9.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 AIN95385.1 - 9.6e-05 22.1 15.3 0.00011 21.9 9.8 1.8 2 0 0 2 2 2 1 Ring finger domain zf-RING_5 PF14634.1 AIN95385.1 - 0.0039 16.8 10.5 0.009 15.7 7.3 1.7 1 1 0 1 1 1 1 zinc-RING finger domain Baculo_IE-1 PF05290.6 AIN95385.1 - 0.19 11.4 3.9 0.33 10.6 2.7 1.3 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) zf-RING_4 PF14570.1 AIN95385.1 - 0.65 9.6 8.3 1.5 8.5 5.8 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Pkinase PF00069.20 AIN95386.1 - 3.4e-40 137.8 0.2 3e-20 72.4 0.3 5.8 5 1 0 5 5 5 4 Protein kinase domain Pkinase_Tyr PF07714.12 AIN95386.1 - 3.2e-14 52.6 0.0 1.8e-08 33.7 0.1 4.1 4 0 0 4 4 4 3 Protein tyrosine kinase FHA PF00498.21 AIN95386.1 - 1.4e-07 31.4 0.0 0.0059 16.6 0.0 2.4 2 0 0 2 2 2 2 FHA domain DUF2076 PF09849.4 AIN95387.1 - 6.9e-07 29.5 7.4 8.2e-07 29.3 5.2 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2076) CHCH PF06747.8 AIN95387.1 - 0.00042 20.1 1.2 0.00058 19.6 0.8 1.2 1 0 0 1 1 1 1 CHCH domain Gly_rich PF12810.2 AIN95387.1 - 0.032 13.8 0.4 0.036 13.6 0.2 1.1 1 0 0 1 1 1 0 Glycine rich protein DUF605 PF04652.11 AIN95387.1 - 0.062 12.6 2.3 0.071 12.4 1.6 1.1 1 0 0 1 1 1 0 Vta1 like DUF1517 PF07466.6 AIN95387.1 - 0.25 10.3 1.6 0.3 10.0 1.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1517) UQ_con PF00179.21 AIN95388.1 - 2.6e-45 153.2 0.0 2.9e-45 153.1 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 AIN95388.1 - 0.0013 18.5 0.0 0.0016 18.2 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.8 AIN95388.1 - 0.0053 16.4 0.2 0.01 15.4 0.1 1.5 1 1 0 1 1 1 1 UEV domain RWD PF05773.17 AIN95388.1 - 0.055 13.3 0.3 0.061 13.2 0.2 1.4 1 1 0 1 1 1 0 RWD domain Ax_dynein_light PF10211.4 AIN95389.1 - 1.1e-09 38.4 3.6 1.1e-09 38.4 2.5 2.7 4 0 0 4 4 4 1 Axonemal dynein light chain DUF1857 PF08982.6 AIN95389.1 - 0.13 11.8 4.2 0.27 10.8 1.2 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1857) CesT PF05932.8 AIN95391.1 - 4e-09 36.3 0.0 9.6e-09 35.1 0.0 1.7 1 0 0 1 1 1 1 Tir chaperone protein (CesT) family PDZ_2 PF13180.1 AIN95391.1 - 4.2e-07 29.7 0.0 2.8e-06 27.1 0.0 2.2 2 0 0 2 2 2 1 PDZ domain DUF974 PF06159.8 AIN95393.1 - 7.5e-09 35.3 0.0 1.1e-07 31.5 0.0 2.1 1 1 0 1 1 1 1 Protein of unknown function (DUF974) WASH_WAHD PF11945.3 AIN95394.1 - 0.0005 19.4 0.0 0.00084 18.7 0.0 1.2 1 0 0 1 1 1 1 WAHD domain of WASH complex Ribosomal_L16 PF00252.13 AIN95395.1 - 5.5e-28 97.3 0.3 7.1e-28 97.0 0.2 1.1 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e DUF1490 PF07371.7 AIN95395.1 - 0.0096 15.8 0.7 0.031 14.2 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF1490) zf-TRM13_CCCH PF11722.3 AIN95395.1 - 1.5 8.3 8.7 19 4.7 4.4 2.4 2 0 0 2 2 2 0 CCCH zinc finger in TRM13 protein NAC PF01849.13 AIN95396.1 - 4.3e-16 58.1 1.7 5.5e-16 57.8 0.1 1.9 2 0 0 2 2 2 1 NAC domain UBA PF00627.26 AIN95396.1 - 0.0055 16.5 0.8 0.017 14.9 0.1 2.1 2 0 0 2 2 2 1 UBA/TS-N domain Myc_N PF01056.13 AIN95396.1 - 0.026 13.6 0.5 0.037 13.1 0.4 1.3 1 0 0 1 1 1 0 Myc amino-terminal region NCD2 PF04905.8 AIN95396.1 - 0.55 10.0 3.3 0.37 10.5 0.2 1.9 2 0 0 2 2 2 0 NAB conserved region 2 (NCD2) Ribosomal_60s PF00428.14 AIN95396.1 - 3.7 8.0 14.4 0.085 13.2 4.7 2.1 2 0 0 2 2 2 0 60s Acidic ribosomal protein DnaJ PF00226.26 AIN95397.1 - 2.9e-19 68.5 0.1 4.2e-19 68.0 0.1 1.2 1 0 0 1 1 1 1 DnaJ domain Tmemb_185A PF10269.4 AIN95397.1 - 0.00029 20.5 6.9 0.028 14.0 2.9 2.7 2 0 0 2 2 2 2 Transmembrane Fragile-X-F protein Pescadillo_N PF06732.6 AIN95400.1 - 6.5e-108 360.2 6.1 1.4e-107 359.2 4.2 1.5 1 0 0 1 1 1 1 Pescadillo N-terminus BRCT PF00533.21 AIN95400.1 - 7e-08 32.5 0.0 1.9e-07 31.1 0.0 1.8 1 1 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain Pep_deformylase PF01327.16 AIN95401.1 - 1.5e-25 89.4 0.0 2.9e-25 88.4 0.0 1.5 1 0 0 1 1 1 1 Polypeptide deformylase Y_phosphatase2 PF03162.8 AIN95403.1 - 5.8e-53 178.6 0.0 7.7e-53 178.2 0.0 1.1 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3 PF13350.1 AIN95403.1 - 0.0031 17.7 0.0 0.0055 16.9 0.0 1.3 1 0 0 1 1 1 1 Tyrosine phosphatase family Rhomboid PF01694.17 AIN95404.1 - 1.2e-05 25.4 4.7 1.2e-05 25.4 3.3 1.9 2 1 0 2 2 2 1 Rhomboid family Ribosomal_L30 PF00327.15 AIN95405.1 - 0.00021 20.8 0.1 0.001 18.6 0.0 2.1 2 0 0 2 2 2 1 Ribosomal protein L30p/L7e CoA_transf_3 PF02515.12 AIN95406.1 - 0.0011 18.2 0.1 0.0042 16.3 0.1 2.0 1 0 0 1 1 1 1 CoA-transferase family III TPR_12 PF13424.1 AIN95408.1 - 8.8e-06 25.5 1.7 0.1 12.5 0.1 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.1 AIN95408.1 - 0.00049 19.6 0.3 0.0078 15.9 0.1 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat IQ PF00612.22 AIN95408.1 - 0.0017 17.7 0.3 0.0055 16.2 0.2 1.9 1 0 0 1 1 1 1 IQ calmodulin-binding motif TPR_2 PF07719.12 AIN95408.1 - 0.008 16.0 0.3 0.044 13.7 0.0 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.1 AIN95408.1 - 0.05 13.2 0.3 0.25 10.9 0.0 2.1 2 0 0 2 2 2 0 TPR repeat TPR_1 PF00515.23 AIN95408.1 - 0.053 13.1 1.5 0.074 12.6 0.1 1.9 2 0 0 2 2 2 0 Tetratricopeptide repeat Cmc1 PF08583.5 AIN95411.1 - 4.9e-05 23.0 1.7 7e-05 22.5 1.2 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like Ndufs5 PF10200.4 AIN95411.1 - 0.018 14.9 1.2 0.033 14.1 0.7 1.4 1 1 0 1 1 1 0 NADH:ubiquinone oxidoreductase, NDUFS5-15kDa CTDII PF01556.13 AIN95412.1 - 2.5e-28 97.7 3.2 3.2e-22 78.2 0.1 3.3 3 0 0 3 3 3 3 DnaJ C terminal domain DnaJ PF00226.26 AIN95412.1 - 3.6e-22 77.8 0.8 1e-21 76.4 0.4 1.8 2 0 0 2 2 2 1 DnaJ domain DnaJ_CXXCXGXG PF00684.14 AIN95412.1 - 2.1e-08 34.1 26.1 3.9e-08 33.2 18.1 1.5 1 0 0 1 1 1 1 DnaJ central domain Ribosomal_L16 PF00252.13 AIN95413.1 - 5.5e-28 97.3 0.3 7.1e-28 97.0 0.2 1.1 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e DUF1490 PF07371.7 AIN95413.1 - 0.0096 15.8 0.7 0.031 14.2 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF1490) zf-TRM13_CCCH PF11722.3 AIN95413.1 - 1.5 8.3 8.7 19 4.7 4.4 2.4 2 0 0 2 2 2 0 CCCH zinc finger in TRM13 protein ADK PF00406.17 AIN95414.1 - 4.4e-39 133.7 0.0 5.3e-39 133.5 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase AAA_18 PF13238.1 AIN95414.1 - 5.7e-07 29.8 0.0 1e-06 29.0 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 AIN95414.1 - 7.2e-07 29.1 0.0 1.7e-06 27.9 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 AIN95414.1 - 2.4e-06 28.3 0.1 4.2e-06 27.5 0.1 1.6 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.1 AIN95414.1 - 0.025 14.5 0.2 0.074 13.0 0.0 1.9 2 1 0 2 2 2 0 AAA domain FYVE PF01363.16 AIN95416.1 - 0.73 9.7 3.9 0.21 11.4 0.3 1.9 2 0 0 2 2 2 0 FYVE zinc finger DZR PF12773.2 AIN95416.1 - 0.87 9.4 7.5 18 5.2 0.1 3.0 2 1 0 2 2 2 0 Double zinc ribbon Nop14 PF04147.7 AIN95418.1 - 0.00061 17.8 28.9 0.00081 17.4 20.0 1.1 1 0 0 1 1 1 1 Nop14-like family YL1 PF05764.8 AIN95418.1 - 0.00086 18.9 20.2 0.0012 18.5 14.0 1.3 1 0 0 1 1 1 1 YL1 nuclear protein Daxx PF03344.10 AIN95418.1 - 0.0029 16.1 22.1 0.0034 15.9 15.3 1.1 1 0 0 1 1 1 1 Daxx Family CDC45 PF02724.9 AIN95418.1 - 0.003 15.6 15.9 0.0037 15.3 11.0 1.2 1 0 0 1 1 1 1 CDC45-like protein TFIIF_alpha PF05793.7 AIN95418.1 - 0.0034 15.8 21.3 0.0042 15.5 14.8 1.2 1 0 0 1 1 1 1 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) BUD22 PF09073.5 AIN95418.1 - 0.0045 16.1 20.5 0.007 15.4 14.2 1.3 1 0 0 1 1 1 1 BUD22 SDA1 PF05285.7 AIN95418.1 - 0.028 13.6 25.4 0.039 13.2 17.6 1.2 1 0 0 1 1 1 0 SDA1 DUF2201_N PF13203.1 AIN95418.1 - 0.063 12.4 4.1 0.093 11.8 2.8 1.3 1 0 0 1 1 1 0 Putative metallopeptidase domain DUF1510 PF07423.6 AIN95418.1 - 0.57 9.5 17.3 0.83 8.9 12.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Mpp10 PF04006.7 AIN95418.1 - 0.61 8.3 25.0 0.84 7.9 17.3 1.1 1 0 0 1 1 1 0 Mpp10 protein Astro_capsid PF03115.9 AIN95418.1 - 2.1 6.4 7.0 2.5 6.2 4.8 1.1 1 0 0 1 1 1 0 Astrovirus capsid protein precursor SAPS PF04499.10 AIN95418.1 - 2.8 6.4 7.2 3.9 6.0 5.0 1.3 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Voltage_CLC PF00654.15 AIN95419.1 - 1.2e-85 287.6 24.6 1.2e-85 287.6 17.0 1.7 2 0 0 2 2 2 1 Voltage gated chloride channel CBS PF00571.23 AIN95419.1 - 2.5e-08 33.5 4.7 0.00052 19.7 0.0 3.6 4 0 0 4 4 4 2 CBS domain TAT_signal PF10518.4 AIN95419.1 - 0.02 14.8 0.1 0.02 14.8 0.0 3.8 3 0 0 3 3 3 0 TAT (twin-arginine translocation) pathway signal sequence DUF947 PF06102.7 AIN95420.1 - 4.7e-17 62.3 6.1 2e-16 60.2 4.2 1.8 1 1 0 1 1 1 1 Domain of unknown function (DUF947) DUF1660 PF07874.6 AIN95420.1 - 0.13 12.5 1.3 0.25 11.6 0.9 1.4 1 0 0 1 1 1 0 Prophage protein (DUF1660) COPI_assoc PF08507.5 AIN95421.1 - 4.9e-12 45.7 10.6 6.7e-12 45.2 7.3 1.2 1 0 0 1 1 1 1 COPI associated protein SP2 PF03014.9 AIN95421.1 - 0.057 11.2 0.4 0.072 10.9 0.3 1.1 1 0 0 1 1 1 0 Structural protein 2 OAD_gamma PF04277.8 AIN95421.1 - 0.074 13.4 2.4 11 6.4 0.0 2.8 2 0 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain DUF4418 PF14387.1 AIN95421.1 - 2.3 7.9 5.7 1.7 8.4 0.7 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4418) CD20 PF04103.10 AIN95421.1 - 6 6.7 16.9 0.21 11.5 0.9 2.8 2 1 1 3 3 3 0 CD20-like family Acyltransferase PF01553.16 AIN95422.1 - 1e-12 47.6 0.1 1.6e-12 47.0 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase Acyltransferase PF01553.16 AIN95423.1 - 5e-12 45.4 0.0 9.2e-12 44.5 0.0 1.5 1 0 0 1 1 1 1 Acyltransferase DUF349 PF03993.7 AIN95423.1 - 0.27 11.3 2.9 0.58 10.3 2.0 1.4 1 0 0 1 1 1 0 Domain of Unknown Function (DUF349) Tcf25 PF04910.9 AIN95426.1 - 3.3e-72 243.4 0.0 9.3e-72 241.9 0.0 1.6 2 0 0 2 2 2 1 Transcriptional repressor TCF25 eIF3_subunit PF08597.5 AIN95426.1 - 0.19 11.2 13.0 0.39 10.2 9.0 1.4 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit DALR_1 PF05746.10 AIN95428.1 - 0.06 13.3 0.4 0.29 11.0 0.1 1.9 1 1 1 2 2 2 0 DALR anticodon binding domain DUF1664 PF07889.7 AIN95429.1 - 2.7 7.8 8.0 0.22 11.3 1.8 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) SCO1-SenC PF02630.9 AIN95430.1 - 3.7e-41 140.6 0.0 5.3e-41 140.1 0.0 1.2 1 0 0 1 1 1 1 SCO1/SenC AhpC-TSA PF00578.16 AIN95430.1 - 0.075 12.7 0.0 0.18 11.4 0.0 1.7 1 0 0 1 1 1 0 AhpC/TSA family Phage_T4_Ndd PF06591.6 AIN95432.1 - 0.027 14.0 0.0 0.037 13.5 0.0 1.1 1 0 0 1 1 1 0 T4-like phage nuclear disruption protein (Ndd) FBPase PF00316.15 AIN95433.1 - 1.3e-108 362.7 0.0 1.6e-108 362.4 0.0 1.0 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase DUF3733 PF12534.3 AIN95433.1 - 0.068 12.4 0.1 0.6 9.4 0.1 2.1 2 0 0 2 2 2 0 Leucine-rich repeat containing protein 8 Methyltransf_21 PF05050.7 AIN95434.1 - 1e-13 51.6 0.0 2.1e-08 34.2 0.0 2.1 2 0 0 2 2 2 2 Methyltransferase FkbM domain Methyltransf_18 PF12847.2 AIN95434.1 - 3.4e-05 24.3 0.0 0.00015 22.3 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_22 PF13383.1 AIN95434.1 - 0.02 14.4 0.1 0.03 13.8 0.1 1.2 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_26 PF13659.1 AIN95434.1 - 0.027 14.4 4.9 0.022 14.7 2.0 2.1 2 1 0 2 2 2 0 Methyltransferase domain Methyltransf_12 PF08242.7 AIN95434.1 - 0.091 13.2 0.0 0.22 12.0 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.9 AIN95434.1 - 0.14 11.5 0.0 0.25 10.6 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain RRM_5 PF13893.1 AIN95435.1 - 4.5e-22 77.6 0.1 7.8e-10 38.4 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 AIN95435.1 - 3.2e-13 49.1 0.0 1.9e-05 24.2 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 AIN95435.1 - 1e-12 47.8 0.0 3.3e-07 30.1 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) CDC48_2 PF02933.12 AIN95435.1 - 0.00033 20.2 0.0 0.00072 19.1 0.0 1.6 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), domain 2 Calcipressin PF04847.7 AIN95435.1 - 0.0086 15.6 0.5 0.27 10.7 0.1 2.4 2 0 0 2 2 2 1 Calcipressin PAT1 PF09770.4 AIN95435.1 - 7.4 4.6 18.3 9 4.3 12.7 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Syntaxin-6_N PF09177.6 AIN95436.1 - 0.33 11.3 2.8 2.3 8.7 0.2 3.0 2 0 0 2 2 2 0 Syntaxin 6, N-terminal AAA_9 PF12781.2 AIN95436.1 - 0.65 8.8 0.0 1.2 7.9 0.0 1.3 1 0 0 1 1 1 0 ATP-binding dynein motor region D5 PolyA_pol PF01743.15 AIN95437.1 - 4.3e-28 98.0 0.0 8.8e-28 97.0 0.0 1.6 1 0 0 1 1 1 1 Poly A polymerase head domain PolyA_pol_RNAbd PF12627.2 AIN95437.1 - 8.5e-08 31.6 0.1 2.1e-07 30.3 0.1 1.6 1 0 0 1 1 1 1 Probable RNA and SrmB- binding site of polymerase A Tenui_N PF05733.6 AIN95437.1 - 0.16 11.2 0.1 0.29 10.4 0.1 1.3 1 0 0 1 1 1 0 Tenuivirus/Phlebovirus nucleocapsid protein LRR_6 PF13516.1 AIN95438.1 - 2.5e-06 26.9 0.0 0.33 11.1 0.0 3.8 4 0 0 4 4 4 2 Leucine Rich repeat LRR_4 PF12799.2 AIN95438.1 - 2.2e-05 23.9 0.0 0.044 13.4 0.0 3.7 2 1 1 4 4 4 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 AIN95438.1 - 0.00015 21.4 0.1 1.1 9.1 0.0 3.2 2 1 0 3 3 3 2 Leucine rich repeat LRR_1 PF00560.28 AIN95438.1 - 0.0095 15.8 0.3 36 4.9 0.0 3.8 3 1 1 4 4 4 1 Leucine Rich Repeat Pkinase PF00069.20 AIN95439.1 - 1.8e-32 112.5 0.0 2.2e-32 112.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AIN95439.1 - 1.5e-16 60.2 0.1 2.5e-16 59.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 AIN95439.1 - 0.0089 15.1 0.0 0.016 14.2 0.0 1.5 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 AIN95439.1 - 0.091 12.4 0.0 0.15 11.7 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family IBP39 PF11422.3 AIN95440.1 - 0.83 9.1 4.7 1.7 8.1 3.2 1.4 1 0 0 1 1 1 0 Initiator binding protein 39 kDa Actin PF00022.14 AIN95441.1 - 9.9e-150 498.3 0.0 1.1e-149 498.1 0.0 1.0 1 0 0 1 1 1 1 Actin ESSS PF10183.4 AIN95441.1 - 0.013 15.9 0.1 0.065 13.6 0.0 2.1 1 1 1 2 2 2 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) EcoRII-C PF09019.6 AIN95441.1 - 0.12 12.1 0.0 0.2 11.4 0.0 1.4 1 0 0 1 1 1 0 EcoRII C terminal Macoilin PF09726.4 AIN95442.1 - 0.00087 17.7 22.4 0.00087 17.7 15.6 5.3 2 1 3 5 5 5 1 Transmembrane protein HALZ PF02183.13 AIN95442.1 - 0.0099 15.5 0.4 0.0099 15.5 0.3 10.1 11 1 1 12 12 12 3 Homeobox associated leucine zipper zf-piccolo PF05715.8 AIN95443.1 - 0.031 14.2 0.5 0.058 13.4 0.4 1.4 1 0 0 1 1 1 0 Piccolo Zn-finger Arf PF00025.16 AIN95444.1 - 3.2e-54 182.8 0.0 3.6e-54 182.6 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.15 AIN95444.1 - 2.7e-09 36.2 0.7 7.7e-07 28.1 0.0 2.4 1 1 1 2 2 2 2 G-protein alpha subunit Miro PF08477.8 AIN95444.1 - 5e-09 36.6 0.3 1.2e-08 35.4 0.0 1.7 2 0 0 2 2 2 1 Miro-like protein SRPRB PF09439.5 AIN95444.1 - 1.1e-08 34.5 0.0 1.4e-08 34.1 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.17 AIN95444.1 - 4.4e-08 32.6 0.0 5.8e-08 32.2 0.0 1.2 1 0 0 1 1 1 1 Ras family MMR_HSR1 PF01926.18 AIN95444.1 - 1.7e-06 27.9 0.0 3.6e-06 26.9 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 AIN95444.1 - 7.1e-06 25.3 0.0 9.3e-06 24.9 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 AIN95444.1 - 2.6e-05 23.7 0.3 0.0064 15.9 0.0 2.2 1 1 1 2 2 2 2 Elongation factor Tu GTP binding domain cobW PF02492.14 AIN95444.1 - 0.038 13.4 0.1 3.6 6.9 0.0 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain FeoB_N PF02421.13 AIN95444.1 - 0.041 13.1 0.1 0.3 10.3 0.1 2.0 1 1 0 1 1 1 0 Ferrous iron transport protein B PduV-EutP PF10662.4 AIN95444.1 - 0.077 12.4 0.0 0.21 11.0 0.0 1.7 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation SRP54 PF00448.17 AIN95444.1 - 0.1 11.9 0.2 0.1 11.9 0.1 1.9 3 0 0 3 3 3 0 SRP54-type protein, GTPase domain Tegument_dsDNA PF12818.2 AIN95444.1 - 0.15 10.9 0.0 0.19 10.5 0.0 1.1 1 0 0 1 1 1 0 dsDNA viral tegument protein Remorin_C PF03763.8 AIN95445.1 - 0.013 14.9 2.5 0.013 14.9 1.8 5.8 2 1 2 5 5 5 0 Remorin, C-terminal region YojJ PF10372.4 AIN95445.1 - 1.4 8.8 13.1 0.33 10.8 0.4 4.8 3 1 1 4 4 4 0 Bacterial membrane-spanning protein N-terminus DUF1528 PF07515.6 AIN95446.1 - 0.75 9.8 3.0 1.7 8.7 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1528) Vault PF01505.13 AIN95447.1 - 1.3e-52 175.5 5.0 3.9e-13 49.2 0.0 5.8 5 0 0 5 5 5 5 Major Vault Protein repeat MVP_shoulder PF11978.3 AIN95447.1 - 1.4e-49 166.8 0.2 2.8e-49 165.8 0.1 1.6 1 0 0 1 1 1 1 Shoulder domain DUF3601 PF12208.3 AIN95447.1 - 0.0041 17.0 0.0 5.2 7.0 0.0 3.6 2 1 1 4 4 4 2 Domain of unknown function (DUF3601) Dynein_light PF01221.13 AIN95448.1 - 6.9e-31 106.0 1.0 7.7e-31 105.9 0.7 1.0 1 0 0 1 1 1 1 Dynein light chain type 1 Vasohibin PF14822.1 AIN95448.1 - 0.12 11.3 0.2 0.18 10.8 0.1 1.3 1 1 0 1 1 1 0 Vasohibin Rrp15p PF07890.7 AIN95449.1 - 1.4e-06 28.3 15.6 3.7e-06 26.9 10.8 1.7 1 1 0 1 1 1 1 Rrp15p NUDIX PF00293.23 AIN95450.1 - 7.8e-16 57.9 0.0 1e-15 57.5 0.0 1.1 1 0 0 1 1 1 1 NUDIX domain Metallophos PF00149.23 AIN95451.1 - 1.7e-29 102.6 0.1 2.6e-29 102.0 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Plus-3 PF03126.13 AIN95451.1 - 0.00086 19.3 0.0 0.0018 18.3 0.0 1.5 1 0 0 1 1 1 1 Plus-3 domain Metallophos_2 PF12850.2 AIN95451.1 - 0.001 18.9 0.0 0.0019 18.0 0.0 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain PspB PF06667.7 AIN95451.1 - 0.14 12.0 0.0 0.29 11.0 0.0 1.4 1 0 0 1 1 1 0 Phage shock protein B Methyltransf_4 PF02390.12 AIN95453.1 - 0.00075 18.6 0.0 0.0011 18.1 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase Pkinase PF00069.20 AIN95454.1 - 2.4e-52 177.6 0.1 5.2e-52 176.5 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AIN95454.1 - 2.3e-28 99.0 0.2 2.2e-26 92.4 0.1 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 AIN95454.1 - 0.00017 21.4 0.0 0.00084 19.1 0.0 1.8 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.9 AIN95454.1 - 0.0038 16.3 0.0 0.0061 15.6 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 AIN95454.1 - 0.01 15.1 0.9 0.02 14.2 0.6 1.5 1 1 0 1 1 1 0 RIO1 family YrbL-PhoP_reg PF10707.4 AIN95454.1 - 0.011 15.0 0.2 0.023 14.0 0.1 1.5 1 1 0 1 1 1 0 PhoP regulatory network protein YrbL DEAD PF00270.24 AIN95455.1 - 2.4e-39 134.5 0.1 4.5e-38 130.4 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase GUCT PF08152.7 AIN95455.1 - 1.6e-26 92.1 0.0 3.2e-26 91.1 0.0 1.5 1 0 0 1 1 1 1 GUCT (NUC152) domain Helicase_C PF00271.26 AIN95455.1 - 4e-24 84.2 0.0 1.7e-23 82.2 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 AIN95455.1 - 0.0017 18.2 0.2 0.036 13.8 0.0 2.3 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit LRR_6 PF13516.1 AIN95456.1 - 1.3e-33 111.2 11.1 0.00029 20.5 0.0 10.1 10 0 0 10 10 10 8 Leucine Rich repeat LRR_4 PF12799.2 AIN95456.1 - 1.8e-14 52.9 3.1 2.4e-06 27.0 0.0 5.3 5 2 2 7 7 7 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 AIN95456.1 - 9.1e-11 40.2 4.0 0.47 10.6 0.0 7.3 8 0 0 8 8 8 4 Leucine Rich Repeat LRR_7 PF13504.1 AIN95456.1 - 6.4e-07 28.5 11.0 5.8 7.5 0.0 7.7 8 0 0 8 8 8 3 Leucine rich repeat LRR_8 PF13855.1 AIN95456.1 - 5.5e-06 26.0 9.3 0.027 14.2 0.4 4.6 4 2 1 5 5 5 3 Leucine rich repeat DUF460 PF04312.8 AIN95457.1 - 9.1 5.8 8.1 0.46 10.0 1.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF460) 2-oxoacid_dh PF00198.18 AIN95459.1 - 4.9e-76 255.0 0.0 6.4e-76 254.6 0.0 1.1 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.17 AIN95459.1 - 5.5e-17 61.1 1.3 7.9e-17 60.6 0.3 1.7 2 0 0 2 2 2 1 Biotin-requiring enzyme E3_binding PF02817.12 AIN95459.1 - 2.5e-12 46.2 0.2 5.7e-12 45.0 0.2 1.7 1 0 0 1 1 1 1 e3 binding domain Biotin_lipoyl_2 PF13533.1 AIN95459.1 - 0.0081 15.8 0.5 0.96 9.1 0.1 3.3 2 1 1 3 3 3 1 Biotin-lipoyl like Fip1 PF05182.8 AIN95460.1 - 1.3e-20 72.3 0.5 2e-20 71.7 0.4 1.3 1 0 0 1 1 1 1 Fip1 motif zf-CCCH PF00642.19 AIN95460.1 - 2.5e-09 36.5 3.6 4.6e-09 35.7 2.5 1.5 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) MMR_HSR1 PF01926.18 AIN95461.1 - 4e-17 62.2 0.1 2.3e-14 53.3 0.0 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase FeoB_N PF02421.13 AIN95461.1 - 2.9e-06 26.6 0.0 1.5e-05 24.3 0.0 2.1 3 0 0 3 3 3 1 Ferrous iron transport protein B AIG1 PF04548.11 AIN95461.1 - 0.00014 21.0 0.1 0.0003 19.9 0.0 1.6 1 0 0 1 1 1 1 AIG1 family Miro PF08477.8 AIN95461.1 - 0.013 16.0 0.0 0.066 13.7 0.0 2.2 2 0 0 2 2 2 0 Miro-like protein GTP_EFTU PF00009.22 AIN95461.1 - 0.022 14.1 0.3 5 6.5 0.0 3.1 2 2 0 2 2 2 0 Elongation factor Tu GTP binding domain DUF258 PF03193.11 AIN95461.1 - 0.036 13.2 0.0 0.072 12.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 Dynamin_N PF00350.18 AIN95461.1 - 0.23 11.2 1.4 0.51 10.1 0.0 2.3 2 0 0 2 2 2 0 Dynamin family DSPc PF00782.15 AIN95463.1 - 3.3e-33 114.0 0.0 5.7e-33 113.3 0.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 AIN95463.1 - 4.9e-05 22.7 0.1 0.00032 20.1 0.0 2.1 2 1 0 2 2 2 1 Protein-tyrosine phosphatase Y_phosphatase2 PF03162.8 AIN95463.1 - 0.038 13.3 0.0 0.067 12.5 0.0 1.3 1 0 0 1 1 1 0 Tyrosine phosphatase family Fe_hyd_lg_C PF02906.9 AIN95464.1 - 4.5e-60 203.3 0.0 1.2e-58 198.6 0.0 2.2 2 0 0 2 2 2 1 Iron only hydrogenase large subunit, C-terminal domain DUF742 PF05331.6 AIN95464.1 - 0.007 15.9 2.8 0.11 12.0 0.2 3.2 1 1 1 3 3 3 1 Protein of unknown function (DUF742) Cortexin PF11057.3 AIN95465.1 - 0.073 12.6 0.0 0.095 12.3 0.0 1.3 1 0 0 1 1 1 0 Cortexin of kidney Ank PF00023.25 AIN95466.1 - 2.3e-06 27.1 0.1 7.4e-06 25.5 0.0 1.8 1 0 0 1 1 1 1 Ankyrin repeat Ank_2 PF12796.2 AIN95466.1 - 8.8e-06 25.9 0.1 2.7e-05 24.4 0.1 2.0 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.1 AIN95466.1 - 0.00013 21.9 0.4 0.00048 20.1 0.0 2.1 2 0 0 2 2 2 1 Ankyrin repeat Ank_5 PF13857.1 AIN95466.1 - 0.00046 20.3 0.0 0.0011 19.0 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_4 PF13637.1 AIN95466.1 - 0.0033 17.8 0.1 0.013 16.0 0.0 2.0 2 0 0 2 2 2 1 Ankyrin repeats (many copies) DUF4381 PF14316.1 AIN95466.1 - 0.14 12.2 3.1 0.34 11.0 2.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) PTPLA PF04387.9 AIN95468.1 - 4.2e-57 192.1 4.7 5.3e-57 191.8 3.2 1.1 1 0 0 1 1 1 1 Protein tyrosine phosphatase-like protein, PTPLA Lig_chan PF00060.21 AIN95468.1 - 0.04 13.6 0.5 1.4 8.6 0.1 2.2 2 0 0 2 2 2 0 Ligand-gated ion channel P16-Arc PF04699.9 AIN95469.1 - 5.8e-06 26.3 0.0 8.4e-06 25.8 0.0 1.2 1 0 0 1 1 1 1 ARP2/3 complex 16 kDa subunit (p16-Arc) Mito_carr PF00153.22 AIN95470.1 - 1.1e-45 153.2 2.1 8.8e-15 54.1 0.0 3.9 3 0 0 3 3 3 3 Mitochondrial carrier protein Glutaredoxin PF00462.19 AIN95472.1 - 3.3e-14 52.6 0.0 4.6e-14 52.1 0.0 1.2 1 0 0 1 1 1 1 Glutaredoxin MCM PF00493.18 AIN95473.1 - 3e-90 302.3 0.0 6.8e-80 268.3 0.0 2.1 2 0 0 2 2 2 2 MCM2/3/5 family AAA_5 PF07728.9 AIN95473.1 - 5.4e-09 35.9 0.0 1e-08 34.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.16 AIN95473.1 - 0.00013 21.1 0.2 0.057 12.5 0.1 2.6 1 1 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.6 AIN95473.1 - 0.00049 19.7 0.0 0.0012 18.4 0.0 1.7 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 AIN95473.1 - 0.015 15.3 0.6 0.039 13.9 0.0 1.9 2 0 0 2 2 2 0 AAA ATPase domain AAA PF00004.24 AIN95473.1 - 0.025 14.7 0.0 0.059 13.5 0.0 1.7 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_2 PF07724.9 AIN95473.1 - 0.17 11.7 0.0 0.37 10.6 0.0 1.5 2 0 0 2 2 2 0 AAA domain (Cdc48 subfamily) Ribosomal_S11 PF00411.14 AIN95474.1 - 0.0045 17.1 0.4 0.016 15.3 0.0 2.1 2 0 0 2 2 2 1 Ribosomal protein S11 Pyr_redox_2 PF07992.9 AIN95475.1 - 2.8e-35 122.0 3.1 9.7e-34 117.0 2.1 3.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.17 AIN95475.1 - 2.1e-28 98.5 0.2 3.9e-28 97.6 0.1 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.22 AIN95475.1 - 1.9e-19 69.8 0.0 4e-15 55.9 0.0 2.7 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 AIN95475.1 - 6e-06 26.4 0.1 0.0061 16.6 0.0 3.2 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 AIN95475.1 - 1.8e-05 23.4 0.9 0.12 10.7 0.0 2.6 3 0 0 3 3 3 2 HI0933-like protein FAD_binding_2 PF00890.19 AIN95475.1 - 0.00012 21.0 1.8 0.0049 15.7 0.6 2.8 3 0 0 3 3 3 1 FAD binding domain DAO PF01266.19 AIN95475.1 - 0.00094 18.1 0.3 2 7.2 0.0 3.0 3 0 0 3 3 3 2 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 AIN95475.1 - 0.027 14.2 0.0 0.085 12.6 0.0 1.8 2 0 0 2 2 2 0 FAD-NAD(P)-binding Thi4 PF01946.12 AIN95475.1 - 0.032 13.3 0.1 0.074 12.1 0.1 1.6 1 0 0 1 1 1 0 Thi4 family GIDA PF01134.17 AIN95475.1 - 0.16 10.8 3.4 0.11 11.3 1.1 1.8 2 1 0 2 2 2 0 Glucose inhibited division protein A DEAD PF00270.24 AIN95476.1 - 1.5e-39 135.2 0.0 2.5e-39 134.4 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 AIN95476.1 - 1.6e-21 75.9 0.4 4e-21 74.6 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 AIN95476.1 - 0.00011 22.0 0.0 0.00038 20.3 0.0 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.1 AIN95476.1 - 0.06 13.4 0.0 0.24 11.5 0.0 2.0 1 1 0 1 1 1 0 AAA domain DUF1639 PF07797.9 AIN95479.1 - 0.1 11.9 0.1 11 5.4 0.1 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1639) Herpes_UL73 PF03554.8 AIN95479.1 - 0.41 10.5 4.8 5 7.0 0.5 2.4 1 1 1 2 2 2 0 UL73 viral envelope glycoprotein Pkinase PF00069.20 AIN95480.1 - 1.4e-68 230.8 0.0 1.8e-68 230.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AIN95480.1 - 3.1e-50 170.6 0.0 4.6e-50 170.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase MORN PF02493.15 AIN95480.1 - 4.2e-40 133.1 44.1 1.3e-09 37.2 2.0 8.8 8 0 0 8 8 8 8 MORN repeat Kinase-like PF14531.1 AIN95480.1 - 0.0032 16.4 0.0 0.0071 15.3 0.0 1.5 2 0 0 2 2 2 1 Kinase-like RIO1 PF01163.17 AIN95480.1 - 0.082 12.2 0.0 0.34 10.2 0.0 1.8 1 1 0 2 2 2 0 RIO1 family SMC_N PF02463.14 AIN95481.1 - 5.9e-59 198.9 0.0 1.2e-58 197.9 0.0 1.7 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 AIN95481.1 - 5.2e-15 56.1 0.1 7.4e-07 29.4 0.0 2.5 2 0 0 2 2 2 2 AAA domain SMC_hinge PF06470.8 AIN95481.1 - 3.3e-10 39.9 0.3 2.7e-09 37.0 0.1 2.5 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_23 PF13476.1 AIN95481.1 - 6.5e-07 29.8 32.2 6.5e-07 29.8 22.3 6.0 2 2 1 3 3 3 1 AAA domain AAA_29 PF13555.1 AIN95481.1 - 4.5e-05 22.9 0.0 0.00011 21.6 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_15 PF13175.1 AIN95481.1 - 0.00012 21.2 0.4 0.0015 17.6 0.0 2.8 3 0 0 3 3 3 1 AAA ATPase domain ABC_tran PF00005.22 AIN95481.1 - 0.035 14.3 20.0 0.22 11.8 2.3 5.7 3 2 0 3 3 3 0 ABC transporter Reo_sigmaC PF04582.7 AIN95481.1 - 6.9 5.7 17.7 6.7 5.7 0.9 3.8 2 2 0 3 3 3 0 Reovirus sigma C capsid protein TPR_2 PF07719.12 AIN95482.1 - 7.1e-25 84.8 19.6 0.00039 20.1 0.0 10.0 10 0 0 10 10 10 6 Tetratricopeptide repeat TPR_11 PF13414.1 AIN95482.1 - 2.5e-21 75.1 23.4 3.3e-07 29.8 0.0 7.3 4 1 5 9 9 9 6 TPR repeat TPR_1 PF00515.23 AIN95482.1 - 1.6e-19 68.5 3.0 0.045 13.3 0.0 8.7 9 0 0 9 9 9 5 Tetratricopeptide repeat TPR_14 PF13428.1 AIN95482.1 - 5.5e-17 60.7 35.2 0.00017 21.8 0.2 10.5 8 2 4 12 12 10 5 Tetratricopeptide repeat TPR_17 PF13431.1 AIN95482.1 - 3.2e-15 54.9 2.7 0.0013 18.7 0.0 8.3 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_16 PF13432.1 AIN95482.1 - 1.5e-14 54.2 51.7 3e-06 27.7 1.4 9.1 7 1 3 11 11 9 6 Tetratricopeptide repeat TPR_12 PF13424.1 AIN95482.1 - 1.5e-14 53.6 27.9 0.007 16.2 0.2 8.5 5 1 4 9 9 9 6 Tetratricopeptide repeat TPR_19 PF14559.1 AIN95482.1 - 2.5e-12 46.9 25.5 2.9e-05 24.3 0.2 8.5 8 1 1 9 9 9 2 Tetratricopeptide repeat Apc3 PF12895.2 AIN95482.1 - 5e-12 45.7 21.6 0.00045 20.3 0.1 6.5 5 2 2 7 7 7 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.1 AIN95482.1 - 5.1e-09 35.2 0.0 2.1 8.3 0.0 7.1 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_7 PF13176.1 AIN95482.1 - 1.1e-06 27.9 2.0 1.2 9.1 0.0 6.8 5 1 1 6 6 6 1 Tetratricopeptide repeat TPR_6 PF13174.1 AIN95482.1 - 8e-06 25.9 14.0 0.52 10.8 0.0 8.5 10 0 0 10 10 8 1 Tetratricopeptide repeat BTAD PF03704.12 AIN95482.1 - 7.4e-05 23.0 1.7 7.4e-05 23.0 1.2 4.6 3 1 1 4 4 4 1 Bacterial transcriptional activator domain TPR_9 PF13371.1 AIN95482.1 - 0.00087 19.0 0.7 0.00087 19.0 0.5 7.2 8 1 1 9 9 7 2 Tetratricopeptide repeat NARP1 PF12569.3 AIN95482.1 - 0.0016 17.3 0.6 1.6 7.3 0.1 2.5 1 1 0 2 2 2 2 NMDA receptor-regulated protein 1 Fis1_TPR_C PF14853.1 AIN95482.1 - 0.016 15.1 2.0 0.93 9.4 0.1 3.6 3 1 1 4 4 3 0 Fis1 C-terminal tetratricopeptide repeat Tctex-1 PF03645.8 AIN95483.1 - 6.4e-26 90.1 1.2 7.1e-26 90.0 0.8 1.0 1 0 0 1 1 1 1 Tctex-1 family Metallophos PF00149.23 AIN95484.1 - 0.00014 21.3 0.0 0.0019 17.6 0.0 2.2 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase NGP1NT PF08153.7 AIN95487.1 - 1.6e-44 150.9 0.4 4.8e-44 149.4 0.3 1.9 1 0 0 1 1 1 1 NGP1NT (NUC091) domain MMR_HSR1 PF01926.18 AIN95487.1 - 2.1e-19 69.5 1.9 3e-16 59.4 0.0 3.1 3 0 0 3 3 3 2 50S ribosome-binding GTPase FeoB_N PF02421.13 AIN95487.1 - 1.6e-05 24.2 0.1 0.00015 21.0 0.0 2.2 2 0 0 2 2 2 1 Ferrous iron transport protein B GTP_EFTU PF00009.22 AIN95487.1 - 0.00012 21.5 0.0 0.084 12.2 0.0 3.5 3 0 0 3 3 3 1 Elongation factor Tu GTP binding domain Dynamin_N PF00350.18 AIN95487.1 - 0.002 17.9 7.7 8.4 6.1 4.8 4.6 2 1 0 2 2 2 2 Dynamin family DUF258 PF03193.11 AIN95487.1 - 0.0032 16.6 0.0 0.0071 15.5 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Miro PF08477.8 AIN95487.1 - 0.0078 16.7 0.2 0.58 10.6 0.0 3.6 3 0 0 3 3 3 1 Miro-like protein AAA_16 PF13191.1 AIN95487.1 - 0.022 14.7 1.0 0.051 13.5 0.0 2.1 3 0 0 3 3 3 0 AAA ATPase domain MobB PF03205.9 AIN95487.1 - 0.037 13.7 2.0 1 9.0 0.0 2.8 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B DUF2360 PF10152.4 AIN95488.1 - 2.9 8.1 14.4 35 4.6 9.9 2.3 1 1 0 1 1 1 0 Predicted coiled-coil domain-containing protein (DUF2360) MFS_1 PF07690.11 AIN95489.1 - 1.3e-32 112.9 28.6 3e-23 82.0 3.0 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2201_N PF13203.1 AIN95489.1 - 0.028 13.6 0.3 0.039 13.1 0.2 1.1 1 0 0 1 1 1 0 Putative metallopeptidase domain IL13 PF03487.8 AIN95489.1 - 0.15 11.7 0.6 0.45 10.2 0.4 1.8 1 0 0 1 1 1 0 Interleukin-13 ATP-synt_ab PF00006.20 AIN95491.1 - 6.3e-69 231.7 0.1 1e-68 231.1 0.1 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain His_kinase PF06580.8 AIN95491.1 - 0.067 13.1 2.2 6.4 6.7 0.0 2.5 2 0 0 2 2 2 0 Histidine kinase ATP-synt_ab_C PF00306.22 AIN95491.1 - 0.079 13.4 0.1 0.3 11.5 0.0 2.0 2 0 0 2 2 2 0 ATP synthase alpha/beta chain, C terminal domain ADH_zinc_N PF00107.21 AIN95492.1 - 4.1e-06 26.3 0.0 8.3e-06 25.3 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase tRNA_m1G_MT PF01746.16 AIN95492.1 - 0.18 11.4 0.0 0.28 10.7 0.0 1.2 1 0 0 1 1 1 0 tRNA (Guanine-1)-methyltransferase LSM PF01423.17 AIN95494.1 - 0.00015 21.2 0.0 0.00049 19.5 0.0 1.8 1 1 0 1 1 1 1 LSM domain Pkinase PF00069.20 AIN95495.1 - 3.1e-69 233.0 0.0 3.6e-69 232.7 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AIN95495.1 - 1.3e-31 109.6 0.0 1.7e-31 109.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 AIN95495.1 - 0.00043 19.3 0.0 0.00072 18.6 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 AIN95495.1 - 0.0071 16.1 0.0 0.038 13.7 0.0 1.9 1 1 1 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 AIN95495.1 - 0.062 12.8 0.0 0.089 12.3 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase Motile_Sperm PF00635.21 AIN95496.1 - 0.00078 19.0 0.0 0.004 16.7 0.0 2.0 2 0 0 2 2 2 1 MSP (Major sperm protein) domain NDUF_B5 PF09781.4 AIN95497.1 - 0.1 11.8 1.5 0.19 10.9 1.1 1.4 1 0 0 1 1 1 0 NADH:ubiquinone oxidoreductase, NDUFB5/SGDH subunit Pyridox_oxidase PF01243.15 AIN95497.1 - 0.12 12.3 0.0 0.28 11.2 0.0 1.6 1 0 0 1 1 1 0 Pyridoxamine 5'-phosphate oxidase DEAD PF00270.24 AIN95499.1 - 5.9e-30 103.9 0.1 4.7e-15 55.4 0.0 2.5 2 0 0 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.26 AIN95499.1 - 2.8e-21 75.1 0.1 5.5e-21 74.2 0.1 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 AIN95499.1 - 0.00016 21.5 0.0 0.00054 19.8 0.0 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit COG4 PF08318.7 AIN95500.1 - 6.4e-37 127.0 0.0 6.6e-34 117.1 0.0 2.4 2 0 0 2 2 2 2 COG4 transport protein RINT1_TIP1 PF04437.8 AIN95500.1 - 2.9e-05 22.8 0.5 9.7e-05 21.0 0.0 2.0 2 0 0 2 2 2 1 RINT-1 / TIP-1 family STAT_alpha PF01017.15 AIN95500.1 - 0.18 11.5 1.1 5.6 6.6 0.0 3.0 3 0 0 3 3 3 0 STAT protein, all-alpha domain Surp PF01805.15 AIN95501.1 - 8.6e-08 31.7 0.0 1.4e-07 31.0 0.0 1.4 1 0 0 1 1 1 1 Surp module ubiquitin PF00240.18 AIN95502.1 - 0.00025 20.3 0.0 0.00051 19.3 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family Kinesin PF00225.18 AIN95503.1 - 6.6e-89 297.8 0.1 1.2e-88 297.0 0.0 1.4 1 0 0 1 1 1 1 Kinesin motor domain Fmp27_WPPW PF10359.4 AIN95503.1 - 0.013 13.9 6.5 0.024 13.0 4.5 1.4 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain Ank_2 PF12796.2 AIN95504.1 - 1e-52 176.4 11.4 3.4e-11 43.3 0.0 11.2 8 4 2 11 11 11 9 Ankyrin repeats (3 copies) Ank PF00023.25 AIN95504.1 - 2.7e-39 131.0 34.6 2.9e-06 26.7 0.0 16.1 16 0 0 16 16 16 10 Ankyrin repeat Ank_5 PF13857.1 AIN95504.1 - 3.3e-38 128.8 24.7 1.7e-05 24.9 0.0 13.5 12 1 1 13 13 13 8 Ankyrin repeats (many copies) Ank_4 PF13637.1 AIN95504.1 - 2.4e-36 123.4 20.6 4.6e-05 23.8 0.1 13.2 13 1 1 14 14 14 8 Ankyrin repeats (many copies) Ank_3 PF13606.1 AIN95504.1 - 8.4e-36 118.4 26.1 9e-05 22.3 0.0 16.7 17 1 0 17 17 17 8 Ankyrin repeat Rhamno_transf PF11316.3 AIN95504.1 - 0.066 12.4 0.6 0.14 11.3 0.1 1.7 2 0 0 2 2 2 0 Putative rhamnosyl transferase Luteo_PO PF04662.8 AIN95504.1 - 0.15 11.5 0.1 8.1 5.8 0.0 2.4 2 0 0 2 2 2 0 Luteovirus P0 protein Nop14 PF04147.7 AIN95504.1 - 0.58 8.0 0.3 0.95 7.3 0.2 1.2 1 0 0 1 1 1 0 Nop14-like family LRR_8 PF13855.1 AIN95505.1 - 0.092 12.5 0.8 0.26 11.0 0.5 1.7 1 0 0 1 1 1 0 Leucine rich repeat LRR_6 PF13516.1 AIN95505.1 - 0.39 10.9 6.7 7.5 6.9 0.0 4.6 5 0 0 5 5 5 0 Leucine Rich repeat LRR_1 PF00560.28 AIN95505.1 - 1.6 9.0 3.8 12 6.3 0.0 3.9 4 0 0 4 4 4 0 Leucine Rich Repeat Nitroreductase PF00881.19 AIN95506.1 - 2.2e-29 102.4 0.0 3e-29 101.9 0.0 1.2 1 0 0 1 1 1 1 Nitroreductase family Mtc PF03820.12 AIN95508.1 - 3.4e-69 232.8 0.3 3.9e-69 232.6 0.2 1.0 1 0 0 1 1 1 1 Tricarboxylate carrier SHIPPO-rpt PF07004.7 AIN95509.1 - 3.9e-56 185.2 191.1 0.013 16.3 0.5 41.1 42 0 0 42 42 42 33 Sperm-tail PG-rich repeat Cyclin PF08613.6 AIN95511.1 - 3.4e-19 69.7 0.0 1.6e-18 67.5 0.0 2.2 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.18 AIN95511.1 - 0.002 17.7 0.0 0.0046 16.5 0.0 1.6 1 0 0 1 1 1 1 Cyclin, N-terminal domain DSPc PF00782.15 AIN95512.1 - 2.5e-18 65.9 0.1 3.7e-06 26.5 0.0 3.4 3 0 0 3 3 3 3 Dual specificity phosphatase, catalytic domain Nucleoplasmin PF03066.10 AIN95512.1 - 0.013 15.0 4.5 0.039 13.4 3.1 1.8 1 0 0 1 1 1 0 Nucleoplasmin CENP-B_dimeris PF09026.5 AIN95512.1 - 0.21 11.8 9.5 0.61 10.3 6.6 1.7 1 0 0 1 1 1 0 Centromere protein B dimerisation domain FAM176 PF14851.1 AIN95512.1 - 0.41 10.3 3.1 1.6 8.4 2.1 2.0 1 0 0 1 1 1 0 FAM176 family Adeno_terminal PF02459.10 AIN95512.1 - 3.4 5.7 6.4 5.5 5.0 4.4 1.2 1 0 0 1 1 1 0 Adenoviral DNA terminal protein DUF605 PF04652.11 AIN95514.1 - 6.5e-76 256.1 27.2 1.6e-75 254.9 18.9 1.5 1 1 0 1 1 1 1 Vta1 like CBM_5_12_2 PF14600.1 AIN95514.1 - 0.1 12.2 0.3 0.24 11.0 0.2 1.6 1 0 0 1 1 1 0 Cellulose-binding domain PAP1 PF08601.5 AIN95514.1 - 3 7.4 12.0 4 7.0 8.3 1.3 1 0 0 1 1 1 0 Transcription factor PAP1 PAT1 PF09770.4 AIN95514.1 - 5 5.2 16.5 5.7 5.0 11.4 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Wyosine_form PF08608.7 AIN95515.1 - 1.2e-22 79.8 1.9 3.2e-16 59.1 0.0 3.5 3 0 0 3 3 3 2 Wyosine base formation Radical_SAM PF04055.16 AIN95515.1 - 1.8e-21 76.9 0.0 3.3e-21 76.1 0.0 1.4 1 0 0 1 1 1 1 Radical SAM superfamily Flavodoxin_1 PF00258.20 AIN95515.1 - 2.1e-12 47.2 0.0 1.7e-11 44.2 0.0 2.3 2 0 0 2 2 2 1 Flavodoxin Kinesin PF00225.18 AIN95516.1 - 4.2e-80 268.9 0.0 3.7e-53 180.3 0.0 2.3 2 0 0 2 2 2 2 Kinesin motor domain MAM33 PF02330.11 AIN95519.1 - 2.5e-08 33.9 0.0 4e-08 33.2 0.0 1.4 1 0 0 1 1 1 1 Mitochondrial glycoprotein zf-MYND PF01753.13 AIN95520.1 - 3.7e-11 42.7 13.5 7.5e-11 41.7 9.4 1.6 1 0 0 1 1 1 1 MYND finger Got1 PF04178.7 AIN95521.1 - 2.3e-31 108.3 15.5 3e-31 107.9 10.7 1.1 1 0 0 1 1 1 1 Got1/Sft2-like family ATP_synt_I PF03899.10 AIN95521.1 - 0.18 11.9 13.1 3 8.0 5.4 2.2 1 1 1 2 2 2 0 ATP synthase I chain DUF4064 PF13273.1 AIN95521.1 - 1.9 8.6 9.3 4 7.5 6.4 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF4064) Claudin_2 PF13903.1 AIN95521.1 - 6.1 6.5 12.4 33 4.1 8.6 2.0 1 1 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction PNP_UDP_1 PF01048.15 AIN95523.1 - 1.2e-39 135.6 0.5 1.6e-39 135.2 0.4 1.1 1 0 0 1 1 1 1 Phosphorylase superfamily zf-C2HC_2 PF13913.1 AIN95525.1 - 8.5e-13 47.5 10.4 8.3e-08 31.6 1.1 2.4 2 0 0 2 2 2 2 zinc-finger of a C2HC-type zf-C2H2 PF00096.21 AIN95525.1 - 0.14 12.5 2.5 18 5.9 0.0 2.7 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-RING_3 PF14369.1 AIN95525.1 - 3.7 7.6 6.1 0.32 11.0 0.2 2.2 2 0 0 2 2 2 0 zinc-finger CPSF_A PF03178.10 AIN95529.1 - 1.1e-17 64.0 0.0 7.6e-14 51.5 0.0 3.1 3 0 0 3 3 3 2 CPSF A subunit region MMS1_N PF10433.4 AIN95529.1 - 1e-07 30.5 0.0 0.0033 15.6 0.0 3.8 4 0 0 4 4 4 3 Mono-functional DNA-alkylating methyl methanesulfonate N-term LRR_8 PF13855.1 AIN95530.1 - 8.6e-06 25.4 0.2 1.9e-05 24.3 0.1 1.6 1 1 0 1 1 1 1 Leucine rich repeat LRR_4 PF12799.2 AIN95530.1 - 2.3e-05 23.8 0.0 0.00025 20.5 0.1 2.4 3 0 0 3 3 3 1 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 AIN95530.1 - 0.029 14.3 0.2 14 6.1 0.0 3.9 5 0 0 5 5 5 0 Leucine Rich Repeat Flagellar_rod PF05149.7 AIN95531.1 - 1.7e-103 345.7 22.7 1.7e-103 345.7 15.8 2.2 3 0 0 3 3 3 1 Paraflagellar rod protein UQ_con PF00179.21 AIN95532.1 - 3.7e-13 49.0 0.0 7.3e-13 48.1 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Kinesin-relat_1 PF12711.2 AIN95533.1 - 0.12 12.7 2.1 0.15 12.5 0.1 2.1 3 0 0 3 3 3 0 Kinesin motor Peptidase_M28 PF04389.12 AIN95534.1 - 1.8e-15 57.1 3.1 0.00045 20.0 0.0 3.3 3 0 0 3 3 3 3 Peptidase family M28 Peptidase_M49 PF03571.10 AIN95535.1 - 2.6e-210 699.1 0.0 3.2e-210 698.8 0.0 1.0 1 0 0 1 1 1 1 Peptidase family M49 DUF1254 PF06863.7 AIN95535.1 - 0.084 12.7 0.1 0.31 10.8 0.1 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF1254) Rhodanese PF00581.15 AIN95536.1 - 7.3e-17 61.7 0.0 7.3e-09 35.9 0.0 2.2 2 0 0 2 2 2 2 Rhodanese-like domain DUF1930 PF09122.5 AIN95538.1 - 5.1e-35 119.0 0.1 9.3e-35 118.2 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1930) Rhodanese PF00581.15 AIN95538.1 - 5.3e-18 65.4 0.0 7.8e-09 35.8 0.0 2.2 2 0 0 2 2 2 2 Rhodanese-like domain Complex1_51K PF01512.12 AIN95539.1 - 6.8e-44 149.2 0.0 1.3e-43 148.3 0.0 1.4 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase 51 Kd subunit NADH_4Fe-4S PF10589.4 AIN95539.1 - 2.5e-18 64.9 0.1 5.8e-18 63.7 0.0 1.7 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region SLBB PF10531.4 AIN95539.1 - 2.5e-07 30.4 0.0 6.2e-07 29.2 0.0 1.7 1 0 0 1 1 1 1 SLBB domain Pet191_N PF10203.4 AIN95540.1 - 0.078 13.0 1.0 0.12 12.4 0.7 1.3 1 0 0 1 1 1 0 Cytochrome c oxidase assembly protein PET191 Cmc1 PF08583.5 AIN95540.1 - 0.096 12.4 2.7 0.11 12.2 1.9 1.1 1 0 0 1 1 1 0 Cytochrome c oxidase biogenesis protein Cmc1 like zf-C3HC4_3 PF13920.1 AIN95541.1 - 0.00028 20.4 6.9 0.00056 19.5 4.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C2HC5 PF06221.8 AIN95541.1 - 0.0078 15.9 5.5 0.0078 15.9 3.8 1.8 1 1 0 1 1 1 1 Putative zinc finger motif, C2HC5-type zf-RING_5 PF14634.1 AIN95541.1 - 0.0087 15.7 7.3 0.014 15.0 5.0 1.4 1 0 0 1 1 1 1 zinc-RING finger domain UPF0506 PF11703.3 AIN95541.1 - 0.23 11.4 3.9 0.55 10.2 2.7 1.7 1 0 0 1 1 1 0 UPF0506 zf-RING_2 PF13639.1 AIN95541.1 - 5.5 6.8 11.3 18 5.2 7.8 1.8 1 1 0 1 1 1 0 Ring finger domain UPF0020 PF01170.13 AIN95542.1 - 2.2e-13 50.1 0.0 7.6e-09 35.3 0.0 2.4 2 0 0 2 2 2 2 Putative RNA methylase family UPF0020 Methyltransf_26 PF13659.1 AIN95542.1 - 7.2e-10 38.9 0.0 1.8e-09 37.6 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain N6_Mtase PF02384.11 AIN95542.1 - 0.0021 17.2 0.0 0.018 14.1 0.0 2.1 2 0 0 2 2 2 1 N-6 DNA Methylase N6_N4_Mtase PF01555.13 AIN95542.1 - 0.0055 16.2 0.0 0.07 12.6 0.0 2.3 2 0 0 2 2 2 1 DNA methylase SR-25 PF10500.4 AIN95542.1 - 0.11 11.8 9.3 0.2 11.1 6.4 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Cren7 PF11520.3 AIN95543.1 - 0.016 14.8 0.3 0.041 13.5 0.2 1.6 1 0 0 1 1 1 0 Chromatin protein Cren7 Band_7 PF01145.20 AIN95545.1 - 2e-27 96.2 0.1 3.7e-27 95.3 0.0 1.4 1 0 0 1 1 1 1 SPFH domain / Band 7 family Band_7_1 PF13421.1 AIN95545.1 - 0.052 13.0 0.1 0.092 12.2 0.1 1.4 1 0 0 1 1 1 0 SPFH domain-Band 7 family DUF3498 PF12004.3 AIN95546.1 - 0.069 12.2 6.3 0.013 14.6 0.7 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3498) HAUS6_N PF14661.1 AIN95546.1 - 6 6.1 12.5 1.1 8.5 4.3 2.4 2 1 0 2 2 2 0 HAUS augmin-like complex subunit 6 N-terminus AFG1_ATPase PF03969.11 AIN95547.1 - 8.6e-80 268.2 1.3 6.1e-73 245.7 0.0 3.3 3 1 0 3 3 3 3 AFG1-like ATPase AAA_22 PF13401.1 AIN95547.1 - 0.0028 17.8 0.0 0.0056 16.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.22 AIN95547.1 - 0.14 12.4 0.0 0.29 11.4 0.0 1.5 1 0 0 1 1 1 0 ABC transporter Bac_DnaA PF00308.13 AIN95547.1 - 0.15 11.6 0.7 0.86 9.2 0.0 2.3 2 1 1 3 3 3 0 Bacterial dnaA protein Lectin_leg-like PF03388.8 AIN95548.1 - 1.3e-11 44.0 0.0 3.8e-07 29.4 0.0 3.0 2 1 1 3 3 3 2 Legume-like lectin family DMAP1 PF05499.7 AIN95548.1 - 0.014 14.9 0.2 0.027 14.0 0.2 1.4 1 0 0 1 1 1 0 DNA methyltransferase 1-associated protein 1 (DMAP1) MORN PF02493.15 AIN95549.1 - 1.5e-22 77.8 39.0 7.9e-08 31.5 1.2 7.2 7 0 0 7 7 7 5 MORN repeat Rad21_Rec8_N PF04825.8 AIN95550.1 - 6.7e-30 103.3 0.1 1.3e-29 102.3 0.1 1.5 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.11 AIN95550.1 - 3.9e-07 29.1 0.1 3.5e-06 26.0 0.0 2.3 2 0 0 2 2 2 1 Conserved region of Rad21 / Rec8 like protein ScpA_ScpB PF02616.9 AIN95550.1 - 0.00022 20.8 0.0 0.44 10.0 0.0 2.3 2 0 0 2 2 2 2 ScpA/B protein Methyltransf_31 PF13847.1 AIN95551.1 - 2.1e-10 40.3 0.0 2.5e-10 40.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 AIN95551.1 - 2.7e-09 37.6 0.0 4.2e-09 36.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 AIN95551.1 - 1e-07 32.3 0.0 2.8e-07 30.9 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 AIN95551.1 - 6.7e-06 26.5 0.0 1.3e-05 25.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain TPMT PF05724.6 AIN95551.1 - 2.2e-05 24.0 0.0 0.0005 19.5 0.0 2.2 2 0 0 2 2 2 1 Thiopurine S-methyltransferase (TPMT) Methyltransf_23 PF13489.1 AIN95551.1 - 2.2e-05 24.2 0.0 4.9e-05 23.1 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain NodS PF05401.6 AIN95551.1 - 3e-05 23.5 0.0 5.4e-05 22.6 0.0 1.4 1 1 0 1 1 1 1 Nodulation protein S (NodS) Methyltransf_8 PF05148.10 AIN95551.1 - 0.00014 21.5 0.0 0.11 12.1 0.0 2.1 2 0 0 2 2 2 2 Hypothetical methyltransferase Methyltransf_25 PF13649.1 AIN95551.1 - 0.0005 20.3 0.0 0.0011 19.3 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain RrnaAD PF00398.15 AIN95551.1 - 0.0026 16.8 0.0 0.0036 16.3 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_32 PF13679.1 AIN95551.1 - 0.0053 16.4 0.0 0.0084 15.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 AIN95551.1 - 0.0057 16.0 0.0 0.028 13.8 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_26 PF13659.1 AIN95551.1 - 0.0082 16.1 0.0 0.053 13.5 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 AIN95551.1 - 0.01 14.9 0.0 0.019 14.0 0.0 1.4 1 1 0 1 1 1 0 Mycolic acid cyclopropane synthetase Pox_MCEL PF03291.11 AIN95551.1 - 0.025 13.4 0.0 0.05 12.4 0.0 1.6 1 1 0 1 1 1 0 mRNA capping enzyme EutQ PF06249.7 AIN95551.1 - 0.041 13.4 0.0 0.082 12.4 0.0 1.5 1 1 0 1 1 1 0 Ethanolamine utilisation protein EutQ RRM_1 PF00076.17 AIN95552.1 - 4.2e-08 32.7 0.0 0.062 12.9 0.0 4.3 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 AIN95552.1 - 5.7e-05 23.0 0.0 0.35 10.8 0.0 3.2 2 1 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) DUF1627 PF07789.7 AIN95552.1 - 0.042 13.3 0.5 0.12 11.8 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1627) vATP-synt_AC39 PF01992.11 AIN95554.1 - 5.9e-63 213.0 0.1 6.6e-63 212.8 0.0 1.0 1 0 0 1 1 1 1 ATP synthase (C/AC39) subunit LRR_4 PF12799.2 AIN95555.1 - 1.7e-12 46.6 0.2 0.0028 17.2 0.0 5.5 4 1 1 5 5 5 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 AIN95555.1 - 7.3e-07 28.3 10.7 1.7 8.9 0.0 6.8 7 0 0 7 7 7 2 Leucine Rich Repeat LRR_8 PF13855.1 AIN95555.1 - 8e-06 25.5 7.8 0.19 11.5 0.0 5.5 5 1 0 6 6 6 2 Leucine rich repeat LRR_6 PF13516.1 AIN95555.1 - 9.5e-05 22.0 10.2 0.27 11.4 0.0 5.7 6 0 0 6 6 6 1 Leucine Rich repeat LRR_7 PF13504.1 AIN95555.1 - 0.0045 16.9 16.8 9.1 6.9 0.0 6.8 7 0 0 7 7 7 2 Leucine rich repeat ATG16 PF08614.6 AIN95555.1 - 0.016 15.0 1.9 0.031 14.0 1.3 1.4 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) CCDC92 PF14916.1 AIN95555.1 - 0.26 10.9 3.0 2.2 7.9 0.2 2.4 2 0 0 2 2 2 0 Coiled-coil domain of unknown function ERM PF00769.14 AIN95555.1 - 3.5 7.1 13.1 0.3 10.5 5.8 1.6 2 0 0 2 2 2 0 Ezrin/radixin/moesin family ELO PF01151.13 AIN95556.1 - 2.6e-46 157.9 32.8 4.7e-46 157.1 22.7 1.3 1 1 0 1 1 1 1 GNS1/SUR4 family PDR_assoc PF08370.6 AIN95556.1 - 8.8 5.9 9.8 1.5 8.3 2.4 2.7 2 1 1 3 3 3 0 Plant PDR ABC transporter associated DUF346 PF03984.8 AIN95557.1 - 0.021 14.2 0.8 0.021 14.2 0.6 2.1 2 0 0 2 2 2 0 Repeat of unknown function (DUF346) Prefoldin_2 PF01920.15 AIN95559.1 - 7.3e-19 67.4 4.0 7.3e-19 67.4 2.8 1.9 1 1 1 2 2 2 1 Prefoldin subunit AAA_13 PF13166.1 AIN95559.1 - 0.11 10.9 4.9 0.12 10.8 3.4 1.0 1 0 0 1 1 1 0 AAA domain DUF972 PF06156.8 AIN95559.1 - 0.6 10.4 11.1 1.7 9.0 0.4 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF972) NAP PF00956.13 AIN95559.1 - 7.4 5.6 8.8 5 6.1 3.8 1.9 1 1 0 2 2 2 0 Nucleosome assembly protein (NAP) APG6 PF04111.7 AIN95559.1 - 8.1 5.3 12.2 3.5 6.6 4.5 2.0 2 0 0 2 2 2 0 Autophagy protein Apg6 DUF2368 PF10166.4 AIN95559.1 - 8.8 5.9 9.0 17 5.0 6.2 1.5 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2368) ATG16 PF08614.6 AIN95559.1 - 9.8 5.9 15.2 11 5.7 0.4 2.1 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) LRR_4 PF12799.2 AIN95560.1 - 1.1e-31 107.9 35.9 9.2e-08 31.5 0.4 6.9 4 1 5 9 9 9 8 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 AIN95560.1 - 2.2e-20 72.1 26.9 6.9e-10 38.5 1.4 6.0 2 2 3 5 5 5 5 Leucine rich repeat LRR_9 PF14580.1 AIN95560.1 - 8.6e-16 57.9 3.8 6e-07 29.1 0.0 3.3 1 1 0 3 3 3 2 Leucine-rich repeat LRR_1 PF00560.28 AIN95560.1 - 2.8e-15 53.9 19.9 0.52 10.5 0.1 10.4 9 2 1 10 10 10 6 Leucine Rich Repeat LRR_7 PF13504.1 AIN95560.1 - 2.8e-10 38.6 18.9 0.79 10.1 0.1 9.9 10 1 0 10 10 10 3 Leucine rich repeat LRR_6 PF13516.1 AIN95560.1 - 4.7e-08 32.3 23.6 0.28 11.3 0.2 9.4 5 2 5 10 10 10 3 Leucine Rich repeat LRR_4 PF12799.2 AIN95561.1 - 2.2e-05 23.9 0.0 0.00032 20.2 0.0 2.6 3 0 0 3 3 3 1 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 AIN95561.1 - 0.00022 20.8 0.1 0.72 10.1 0.0 4.0 4 0 0 4 4 4 2 Leucine Rich Repeat LRR_8 PF13855.1 AIN95561.1 - 0.0047 16.6 0.1 0.035 13.8 0.1 2.3 1 1 1 2 2 2 1 Leucine rich repeat Histone PF00125.19 AIN95562.1 - 2e-12 47.0 0.5 2.4e-12 46.7 0.4 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 AIN95562.1 - 0.0018 18.2 0.4 0.0025 17.8 0.0 1.4 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TAF PF02969.12 AIN95562.1 - 0.004 17.0 0.1 0.0064 16.4 0.1 1.4 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) Bromo_TP PF07524.8 AIN95562.1 - 0.0069 16.0 0.0 0.0089 15.7 0.0 1.2 1 0 0 1 1 1 1 Bromodomain associated TFIID-31kDa PF02291.10 AIN95562.1 - 0.01 15.6 0.0 0.01 15.6 0.0 1.2 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit PCP_red PF08369.5 AIN95562.1 - 0.29 11.0 1.6 0.82 9.5 0.2 2.3 2 0 0 2 2 2 0 Proto-chlorophyllide reductase 57 kD subunit LRR_4 PF12799.2 AIN95563.1 - 1.7e-28 97.7 0.0 0.00013 21.4 0.0 9.4 4 2 6 10 10 10 9 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 AIN95563.1 - 2e-12 46.6 13.9 2.9e-05 23.7 0.0 6.9 4 2 5 9 9 9 5 Leucine rich repeat LRR_6 PF13516.1 AIN95563.1 - 4.5e-11 41.6 16.3 4.6 7.6 0.0 10.6 12 1 1 13 13 13 4 Leucine Rich repeat LRR_1 PF00560.28 AIN95563.1 - 0.00097 18.8 24.6 4.9 7.5 0.0 11.2 11 2 2 13 13 13 1 Leucine Rich Repeat LRR_7 PF13504.1 AIN95563.1 - 0.049 13.8 28.0 12 6.5 0.0 11.0 13 1 0 13 13 13 0 Leucine rich repeat LRR_9 PF14580.1 AIN95563.1 - 0.15 11.6 2.5 6.9 6.1 0.0 3.5 3 1 1 4 4 4 0 Leucine-rich repeat WD40 PF00400.27 AIN95564.1 - 6.9e-71 231.8 29.5 5.9e-14 51.3 0.2 7.4 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 AIN95564.1 - 1.3e-06 26.8 13.7 0.013 13.6 0.2 5.5 2 1 4 6 6 6 3 Nucleoporin Nup120/160 eIF2A PF08662.6 AIN95564.1 - 2.5e-06 27.3 2.3 0.00093 18.9 0.1 3.1 1 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A DUF3354 PF11834.3 AIN95564.1 - 0.074 12.6 0.0 0.16 11.5 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3354) ROS_MUCR PF05443.6 AIN95564.1 - 0.11 12.2 0.5 5 6.9 0.1 2.4 2 0 0 2 2 2 0 ROS/MUCR transcriptional regulator protein MRP-L46 PF11788.3 AIN95565.1 - 2e-08 34.8 0.0 5.7e-08 33.3 0.0 1.8 1 1 0 1 1 1 1 39S mitochondrial ribosomal protein L46 PUF PF00806.14 AIN95566.1 - 2.1e-26 89.8 7.1 2.3e-06 26.7 0.0 6.1 6 0 0 6 6 6 5 Pumilio-family RNA binding repeat Glycolytic PF00274.14 AIN95566.1 - 0.0077 14.6 0.1 0.012 14.0 0.0 1.2 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-I bZIP_1 PF00170.16 AIN95567.1 - 1.4 8.9 12.9 0.32 10.9 0.1 3.7 3 1 0 3 3 3 0 bZIP transcription factor DUF3782 PF12644.2 AIN95567.1 - 2.6 7.9 5.0 3.1 7.6 2.0 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF3782) ABC2_membrane PF01061.19 AIN95569.1 - 3.6e-37 127.5 15.8 3.6e-37 127.5 10.9 1.4 2 0 0 2 2 1 1 ABC-2 type transporter ABC_tran PF00005.22 AIN95569.1 - 6.1e-22 78.3 0.0 9.4e-22 77.7 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 AIN95569.1 - 5.5e-06 26.5 0.0 0.022 14.7 0.0 2.5 2 0 0 2 2 2 2 AAA domain ABC2_membrane_3 PF12698.2 AIN95569.1 - 7e-05 22.0 5.2 7e-05 22.0 3.6 1.4 1 1 0 1 1 1 1 ABC-2 family transporter protein SMC_N PF02463.14 AIN95569.1 - 0.00095 18.4 0.1 0.026 13.7 0.1 2.2 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 AIN95569.1 - 0.0014 18.6 0.1 0.0029 17.6 0.1 1.5 1 0 0 1 1 1 1 AAA ATPase domain DUF258 PF03193.11 AIN95569.1 - 0.0094 15.1 0.0 0.015 14.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 NACHT PF05729.7 AIN95569.1 - 0.0095 15.6 0.0 0.021 14.5 0.0 1.5 1 0 0 1 1 1 1 NACHT domain AAA_23 PF13476.1 AIN95569.1 - 0.013 15.8 0.0 0.02 15.2 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.1 AIN95569.1 - 0.015 16.1 0.0 0.027 15.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.1 AIN95569.1 - 0.016 14.7 0.3 0.034 13.6 0.2 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_19 PF13245.1 AIN95569.1 - 0.021 14.5 0.1 0.058 13.1 0.0 1.8 1 0 0 1 1 1 0 Part of AAA domain FtsK_SpoIIIE PF01580.13 AIN95569.1 - 0.045 13.2 0.2 0.12 11.8 0.1 1.6 2 0 0 2 2 2 0 FtsK/SpoIIIE family DUF87 PF01935.12 AIN95569.1 - 0.045 13.5 0.4 0.078 12.7 0.3 1.3 1 0 0 1 1 1 0 Domain of unknown function DUF87 AAA_10 PF12846.2 AIN95569.1 - 0.073 12.5 0.1 0.15 11.5 0.1 1.5 1 0 0 1 1 1 0 AAA-like domain Zeta_toxin PF06414.7 AIN95569.1 - 0.084 11.9 0.1 0.16 11.0 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_25 PF13481.1 AIN95569.1 - 0.098 12.0 0.1 0.2 11.0 0.1 1.4 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.1 AIN95569.1 - 0.12 12.5 0.1 0.32 11.1 0.1 1.9 1 1 0 1 1 1 0 AAA domain PRK PF00485.13 AIN95569.1 - 0.17 11.3 0.0 0.26 10.8 0.0 1.2 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family AAA_30 PF13604.1 AIN95569.1 - 0.19 11.3 0.1 0.34 10.4 0.1 1.3 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.18 AIN95569.1 - 0.19 11.7 0.0 0.37 10.7 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase NTPase_1 PF03266.10 AIN95569.1 - 0.2 11.3 0.0 1.2 8.7 0.0 2.0 2 0 0 2 2 2 0 NTPase CytochromB561_N PF09786.4 AIN95570.1 - 3.2e-05 22.6 0.1 0.00021 19.9 0.1 2.1 1 1 0 1 1 1 1 Cytochrome B561, N terminal Pro_isomerase PF00160.16 AIN95571.1 - 9.1e-48 162.3 0.7 1.1e-47 162.1 0.5 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD DUF1768 PF08719.6 AIN95572.1 - 2.2e-32 111.9 0.0 2.6e-32 111.7 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1768) Proteasome PF00227.21 AIN95573.1 - 2.2e-27 95.5 0.0 3.3e-27 95.0 0.0 1.2 1 0 0 1 1 1 1 Proteasome subunit VKOR PF07884.9 AIN95574.1 - 0.051 13.4 0.0 0.063 13.1 0.0 1.1 1 0 0 1 1 1 0 Vitamin K epoxide reductase family HD PF01966.17 AIN95575.1 - 1.5e-13 50.7 3.1 2e-13 50.4 0.2 2.1 2 0 0 2 2 2 1 HD domain HDOD PF08668.7 AIN95575.1 - 0.0021 17.3 0.0 0.0037 16.5 0.0 1.3 1 0 0 1 1 1 1 HDOD domain Trm112p PF03966.11 AIN95576.1 - 5.8e-08 32.9 0.0 2.3e-07 31.0 0.0 1.8 1 1 0 1 1 1 1 Trm112p-like protein zinc_ribbon_5 PF13719.1 AIN95576.1 - 0.048 13.2 0.2 0.048 13.2 0.1 1.8 2 0 0 2 2 2 0 zinc-ribbon domain zinc_ribbon_4 PF13717.1 AIN95576.1 - 0.065 12.9 0.2 0.065 12.9 0.1 1.7 2 0 0 2 2 2 0 zinc-ribbon domain Kinesin PF00225.18 AIN95577.1 - 5.6e-70 235.6 0.0 7.7e-70 235.2 0.0 1.2 1 0 0 1 1 1 1 Kinesin motor domain FHA PF00498.21 AIN95580.1 - 2.6e-09 37.0 0.0 2.5e-08 33.9 0.0 2.2 2 0 0 2 2 2 1 FHA domain DUF4490 PF14892.1 AIN95581.1 - 0.0074 15.9 0.4 0.014 14.9 0.3 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4490) Leu_zip PF15294.1 AIN95584.1 - 2.1e-10 40.1 10.5 3.8e-06 26.2 0.6 2.2 1 1 1 2 2 2 2 Leucine zipper Cep57_MT_bd PF06657.8 AIN95584.1 - 0.013 15.4 5.4 0.22 11.4 0.9 2.8 2 1 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 Atg14 PF10186.4 AIN95584.1 - 0.04 12.8 8.7 0.045 12.6 5.3 1.4 1 1 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 3HCDH_N PF02737.13 AIN95584.1 - 0.21 11.2 2.7 0.4 10.3 1.9 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FliJ PF02050.11 AIN95584.1 - 0.69 9.9 18.3 36 4.4 13.0 2.6 1 1 0 1 1 1 0 Flagellar FliJ protein HAUS-augmin3 PF14932.1 AIN95584.1 - 0.89 8.6 11.5 1.1 8.3 0.2 2.4 1 1 0 2 2 2 0 HAUS augmin-like complex subunit 3 TMF_TATA_bd PF12325.3 AIN95584.1 - 1.2 8.8 14.0 0.68 9.6 0.8 2.4 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding Baculo_PEP_C PF04513.7 AIN95584.1 - 2.7 7.8 8.7 7.7 6.3 2.5 2.9 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Occludin_ELL PF07303.8 AIN95584.1 - 2.9 8.6 6.2 4.6 8.0 1.6 2.3 1 1 1 2 2 2 0 Occludin homology domain UPF0449 PF15136.1 AIN95584.1 - 5 7.4 7.2 1.5 9.0 1.4 2.5 1 1 1 2 2 2 0 Uncharacterised protein family UPF0449 GAS PF13851.1 AIN95584.1 - 5.3 6.1 11.2 3.1 6.9 4.5 2.2 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding XRN_N PF03159.13 AIN95585.1 - 9.4e-91 303.4 0.0 1.5e-90 302.7 0.0 1.3 1 0 0 1 1 1 1 XRN 5'-3' exonuclease N-terminus FeoC PF09012.5 AIN95585.1 - 0.96 9.2 2.4 22 4.8 0.0 2.9 3 0 0 3 3 3 0 FeoC like transcriptional regulator FHA PF00498.21 AIN95587.1 - 0.001 19.1 0.0 0.0022 18.1 0.0 1.4 1 0 0 1 1 1 1 FHA domain RNase_H PF00075.19 AIN95588.1 - 7.6e-24 84.5 0.6 3.4e-21 75.9 0.4 2.9 1 1 0 1 1 1 1 RNase H zf-MYND PF01753.13 AIN95589.1 - 7.2e-12 44.9 11.8 7.2e-12 44.9 8.2 2.0 3 0 0 3 3 3 1 MYND finger Haem_bd PF14376.1 AIN95589.1 - 0.16 11.6 1.9 4 7.1 0.0 2.2 2 0 0 2 2 2 0 Haem-binding domain DUF4599 PF15371.1 AIN95589.1 - 1.8 8.7 5.5 19 5.4 0.2 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF4599) TPR_11 PF13414.1 AIN95591.1 - 2e-05 24.1 5.6 2e-05 24.1 3.9 2.1 2 0 0 2 2 2 1 TPR repeat TPR_2 PF07719.12 AIN95591.1 - 0.032 14.1 10.1 0.73 9.8 0.6 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_19 PF14559.1 AIN95591.1 - 0.22 11.9 8.5 1.3 9.4 5.9 2.5 1 1 0 1 1 1 0 Tetratricopeptide repeat TPR_1 PF00515.23 AIN95591.1 - 0.28 10.8 4.1 2.1 8.1 0.3 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat Sel1 PF08238.7 AIN95591.1 - 0.32 11.7 7.0 0.62 10.7 0.3 2.6 2 0 0 2 2 2 0 Sel1 repeat TPR_14 PF13428.1 AIN95591.1 - 6.5 7.6 25.7 2 9.2 1.2 5.8 3 1 2 5 5 5 0 Tetratricopeptide repeat Peptidase_S9 PF00326.16 AIN95592.1 - 3.1e-34 118.0 0.0 5.2e-34 117.3 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Peptidase_S9_N PF02897.10 AIN95592.1 - 1.1e-24 86.8 0.0 2.2e-24 85.8 0.0 1.4 1 1 0 1 1 1 1 Prolyl oligopeptidase, N-terminal beta-propeller domain 3Beta_HSD PF01073.14 AIN95593.1 - 1.6e-28 99.1 0.0 2.1e-28 98.8 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 AIN95593.1 - 3.8e-19 69.0 0.0 5.1e-19 68.6 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 AIN95593.1 - 4.4e-10 38.9 0.0 6.6e-10 38.3 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.1 AIN95593.1 - 3.3e-08 33.7 0.0 4.5e-08 33.3 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding RmlD_sub_bind PF04321.12 AIN95593.1 - 1.4e-05 24.1 0.0 2e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.10 AIN95593.1 - 0.00041 19.3 0.0 0.00065 18.6 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NmrA PF05368.8 AIN95593.1 - 0.019 14.2 0.0 0.032 13.5 0.0 1.3 1 0 0 1 1 1 0 NmrA-like family Gln-synt_C PF00120.19 AIN95595.1 - 5.3e-47 160.1 0.0 6.5e-47 159.8 0.0 1.1 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain Gln-synt_N PF03951.14 AIN95595.1 - 1.1e-15 56.9 0.0 2e-15 56.1 0.0 1.4 1 0 0 1 1 1 1 Glutamine synthetase, beta-Grasp domain SnoaL_3 PF13474.1 AIN95595.1 - 0.14 12.2 0.0 0.27 11.2 0.0 1.4 1 0 0 1 1 1 0 SnoaL-like domain zf-CCCH PF00642.19 AIN95596.1 - 1.5e-06 27.7 1.5 1.5e-06 27.7 1.0 2.0 2 0 0 2 2 2 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.1 AIN95596.1 - 0.011 15.6 1.9 0.011 15.6 1.3 1.9 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type OrfB_Zn_ribbon PF07282.6 AIN95598.1 - 0.095 12.3 0.4 0.23 11.1 0.3 1.6 1 0 0 1 1 1 0 Putative transposase DNA-binding domain Ribosomal_L19e PF01280.15 AIN95599.1 - 1.1e-59 200.4 12.8 1.1e-59 200.4 8.9 2.1 1 1 1 2 2 2 1 Ribosomal protein L19e APG6 PF04111.7 AIN95599.1 - 2.2 7.2 9.9 3 6.8 6.8 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 Hid1 PF12722.2 AIN95599.1 - 4.3 4.9 6.5 5.4 4.5 4.5 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein LCD1 PF09798.4 AIN95599.1 - 9 4.1 8.4 12 3.7 5.8 1.1 1 0 0 1 1 1 0 DNA damage checkpoint protein Kinesin PF00225.18 AIN95601.1 - 4.9e-12 45.2 0.2 7.3e-05 21.6 0.0 2.8 2 0 0 2 2 2 2 Kinesin motor domain DUF3074 PF11274.3 AIN95601.1 - 0.0091 15.6 1.0 0.021 14.4 0.0 2.1 3 0 0 3 3 3 1 Protein of unknown function (DUF3074) TMF_DNA_bd PF12329.3 AIN95601.1 - 0.016 14.9 6.3 0.016 14.9 4.4 2.6 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding AAA_13 PF13166.1 AIN95601.1 - 0.066 11.6 5.1 0.099 11.0 3.5 1.2 1 0 0 1 1 1 0 AAA domain Mnd1 PF03962.10 AIN95601.1 - 3.3 7.3 23.4 8.6 5.9 0.8 2.8 1 1 2 3 3 3 0 Mnd1 family V_ATPase_I PF01496.14 AIN95601.1 - 5.3 4.7 8.3 7.9 4.1 5.7 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family TPR_12 PF13424.1 AIN95602.1 - 3.1e-07 30.2 0.7 1.2e-05 25.1 0.1 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.1 AIN95602.1 - 8.8e-07 28.4 3.7 5e-06 26.0 0.2 2.5 2 0 0 2 2 2 1 TPR repeat TPR_1 PF00515.23 AIN95602.1 - 0.00021 20.7 3.1 0.027 14.0 0.0 3.5 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_10 PF13374.1 AIN95602.1 - 0.0006 19.6 2.7 0.011 15.6 0.0 4.0 4 1 0 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.12 AIN95602.1 - 0.0077 16.0 1.5 0.053 13.4 0.0 3.0 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.1 AIN95602.1 - 0.0096 15.6 0.1 1 9.3 0.0 3.1 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.1 AIN95602.1 - 0.43 10.9 5.4 0.94 9.8 1.9 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat NAD_kinase PF01513.16 AIN95604.1 - 2.3e-14 52.8 0.0 4.4e-14 51.9 0.0 1.4 1 0 0 1 1 1 1 ATP-NAD kinase Cnd2 PF05786.9 AIN95605.1 - 4.1e-24 85.1 0.2 3.8e-13 48.8 0.4 2.4 2 0 0 2 2 2 2 Condensin complex subunit 2 SpoU_methylase PF00588.14 AIN95608.1 - 1.4e-14 54.1 0.0 5.1e-09 36.1 0.0 3.1 3 0 0 3 3 3 2 SpoU rRNA Methylase family SpoU_sub_bind PF08032.7 AIN95608.1 - 0.00017 21.6 0.0 0.0014 18.7 0.0 2.2 2 0 0 2 2 2 1 RNA 2'-O ribose methyltransferase substrate binding U-box PF04564.10 AIN95609.1 - 6.2e-12 45.2 0.0 1.2e-11 44.4 0.0 1.4 1 0 0 1 1 1 1 U-box domain LRR_4 PF12799.2 AIN95610.1 - 6e-20 70.4 0.0 0.015 14.9 0.0 9.4 9 1 0 9 9 9 5 Leucine Rich repeats (2 copies) LRR_6 PF13516.1 AIN95610.1 - 1.4e-08 33.8 13.6 3.8 7.8 0.0 10.0 11 0 0 11 11 11 4 Leucine Rich repeat LRR_8 PF13855.1 AIN95610.1 - 1.2e-07 31.3 7.5 5.6 6.7 0.0 8.0 8 2 1 9 9 9 4 Leucine rich repeat Maf_N PF08383.6 AIN95611.1 - 0.087 12.3 0.1 0.087 12.3 0.0 2.1 2 0 0 2 2 2 0 Maf N-terminal region dUTPase_2 PF08761.6 AIN95614.1 - 2.2e-39 135.2 0.0 2.9e-39 134.8 0.0 1.1 1 0 0 1 1 1 1 dUTPase Mgm101p PF06420.7 AIN95614.1 - 0.042 13.1 0.0 0.065 12.5 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial genome maintenance MGM101 Ribosomal_L23 PF00276.15 AIN95615.1 - 5.8e-20 71.0 2.0 5.8e-20 71.0 1.4 2.4 2 1 0 2 2 2 1 Ribosomal protein L23 Ribosomal_L23eN PF03939.8 AIN95615.1 - 8.3e-12 44.9 12.4 8.3e-12 44.9 8.6 2.1 2 1 0 2 2 2 1 Ribosomal protein L23, N-terminal domain Late_protein_L2 PF00513.13 AIN95615.1 - 0.0002 20.3 1.3 0.00022 20.2 0.9 1.0 1 0 0 1 1 1 1 Late Protein L2 PHD PF00628.24 AIN95617.1 - 0.00043 19.9 0.7 0.00043 19.9 0.5 1.9 2 0 0 2 2 2 1 PHD-finger PHF5 PF03660.9 AIN95617.1 - 0.52 10.3 6.1 1.3 9.1 0.3 3.2 3 0 0 3 3 3 0 PHF5-like protein zf-RING_2 PF13639.1 AIN95617.1 - 0.74 9.6 6.4 1.2 8.9 1.7 2.5 2 0 0 2 2 2 0 Ring finger domain Pro_CA PF00484.14 AIN95618.1 - 1.3e-39 135.5 3.7 1.7e-39 135.2 1.3 2.0 2 1 0 2 2 2 1 Carbonic anhydrase DUF89 PF01937.14 AIN95619.1 - 6.4e-41 140.3 0.1 1.2e-22 80.1 0.0 4.3 4 0 0 4 4 4 4 Protein of unknown function DUF89 Put_Phosphatase PF06888.7 AIN95619.1 - 4.7e-31 107.7 1.8 4e-14 52.3 0.0 3.3 2 1 1 3 3 3 3 Putative Phosphatase HAD PF12710.2 AIN95619.1 - 0.00057 20.1 0.2 0.011 15.9 0.2 2.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Pkinase PF00069.20 AIN95620.1 - 6.5e-47 159.8 0.0 3.3e-46 157.5 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AIN95620.1 - 1e-30 106.6 0.0 1.6e-22 79.8 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase FHA PF00498.21 AIN95620.1 - 2.3e-09 37.2 0.1 7.3e-09 35.6 0.0 1.9 2 0 0 2 2 2 1 FHA domain Kinase-like PF14531.1 AIN95620.1 - 0.0006 18.8 0.1 0.0014 17.6 0.0 1.5 2 0 0 2 2 2 1 Kinase-like PAS PF00989.19 AIN95620.1 - 0.0015 18.3 0.0 0.24 11.2 0.0 2.8 2 0 0 2 2 2 1 PAS fold PAS_9 PF13426.1 AIN95620.1 - 0.0017 18.7 0.0 2.6 8.4 0.0 2.5 2 0 0 2 2 2 2 PAS domain Kdo PF06293.9 AIN95620.1 - 0.15 11.1 0.0 0.26 10.3 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 AIN95620.1 - 0.44 9.8 0.0 0.76 9.0 0.0 1.3 1 0 0 1 1 1 0 RIO1 family Paramyxo_P PF01806.12 AIN95620.1 - 3.8 6.6 0.0 6.5 5.9 0.0 1.2 1 0 0 1 1 1 0 Paramyxovirinae P phosphoprotein C-terminal region Prenyltrans_1 PF13243.1 AIN95621.1 - 5.9e-24 84.1 5.1 3.2e-09 36.7 0.1 5.1 3 1 3 6 6 6 4 Prenyltransferase-like Prenyltrans PF00432.16 AIN95621.1 - 7.2e-24 83.0 15.2 2e-09 36.8 0.0 5.4 5 1 0 5 5 5 4 Prenyltransferase and squalene oxidase repeat Prenyltrans_2 PF13249.1 AIN95621.1 - 2.3e-23 82.7 3.0 4.4e-12 46.4 0.1 5.4 4 2 1 5 5 5 4 Prenyltransferase-like Pec_lyase PF09492.5 AIN95621.1 - 4e-07 29.5 0.3 0.12 11.5 0.0 4.0 3 1 1 4 4 4 3 Pectic acid lyase A2M_comp PF07678.9 AIN95621.1 - 0.041 13.1 0.1 0.28 10.3 0.0 2.3 2 1 0 2 2 2 0 A-macroglobulin complement component Cmc1 PF08583.5 AIN95624.1 - 0.00023 20.8 4.2 0.00042 20.0 2.9 1.4 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like NDUF_B7 PF05676.8 AIN95624.1 - 0.00074 18.8 3.3 0.0013 18.0 2.3 1.3 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) NPBW PF15180.1 AIN95624.1 - 0.13 11.9 2.4 10 5.7 0.0 2.3 1 1 1 2 2 2 0 Neuropeptides B and W CHCH PF06747.8 AIN95624.1 - 1 9.3 4.9 1.7 8.6 3.4 1.4 1 0 0 1 1 1 0 CHCH domain Ctf8 PF09696.5 AIN95625.1 - 1.2e-05 25.0 0.0 2.4 7.9 0.0 3.2 3 0 0 3 3 3 3 Ctf8 CSS-motif PF12792.2 AIN95625.1 - 0.019 14.3 0.0 0.034 13.4 0.0 1.3 1 0 0 1 1 1 0 CSS motif domain associated with EAL zf-ribbon_3 PF13248.1 AIN95626.1 - 2.2 7.5 6.5 0.41 9.9 1.3 2.2 2 0 0 2 2 2 0 zinc-ribbon domain Ank_5 PF13857.1 AIN95627.1 - 2.3e-10 40.3 2.1 0.00077 19.6 0.0 3.3 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.2 AIN95627.1 - 2.5e-09 37.3 0.1 1.3e-08 35.0 0.0 2.1 1 1 1 2 2 2 1 Ankyrin repeats (3 copies) C2 PF00168.25 AIN95627.1 - 1.3e-08 34.5 0.0 2.8e-08 33.4 0.0 1.6 1 0 0 1 1 1 1 C2 domain Ank PF00023.25 AIN95627.1 - 2.3e-08 33.4 0.2 0.0048 16.6 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.1 AIN95627.1 - 3.4e-07 30.5 0.6 0.0015 18.9 0.0 3.1 2 1 0 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 AIN95627.1 - 2.4e-05 24.1 0.1 0.1 12.8 0.0 2.9 2 0 0 2 2 2 2 Ankyrin repeat YEATS PF03366.11 AIN95628.1 - 1.7e-16 59.6 0.0 6.7e-16 57.7 0.0 1.9 1 1 0 1 1 1 1 YEATS family PALP PF00291.20 AIN95629.1 - 7.4e-58 196.1 0.4 8.3e-58 196.0 0.3 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme HlyIII PF03006.15 AIN95631.1 - 1.4e-18 67.0 9.6 5.6e-12 45.5 1.5 2.4 2 0 0 2 2 2 2 Haemolysin-III related RRM_1 PF00076.17 AIN95633.1 - 2.8e-25 87.7 0.0 3.1e-14 52.3 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 AIN95633.1 - 2.8e-19 68.8 0.0 1.4e-09 37.8 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 AIN95633.1 - 1.9e-06 27.6 0.0 0.0016 18.2 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PRD_Mga PF08270.6 AIN95635.1 - 0.52 9.5 0.0 0.89 8.7 0.0 1.2 1 0 0 1 1 1 0 M protein trans-acting positive regulator (MGA) PRD domain Phage_tail_T PF06223.7 AIN95637.1 - 0.0011 19.3 0.7 0.0026 18.1 0.1 1.8 2 0 0 2 2 2 1 Minor tail protein T ADIP PF11559.3 AIN95637.1 - 0.04 13.8 6.9 2.5 7.9 0.0 2.4 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding SNARE PF05739.14 AIN95637.1 - 0.38 10.4 8.3 0.035 13.7 1.8 2.1 2 0 0 2 2 2 0 SNARE domain DUF4618 PF15397.1 AIN95637.1 - 0.98 8.6 5.6 5.7 6.1 0.0 2.9 2 1 0 2 2 2 0 Domain of unknown function (DUF4618) LNS2 PF08235.8 AIN95638.1 - 3.9e-54 182.4 0.0 6.2e-54 181.8 0.0 1.3 1 0 0 1 1 1 1 LNS2 (Lipin/Ned1/Smp2) Lipin_N PF04571.9 AIN95638.1 - 1.3e-18 66.6 0.0 3.9e-18 65.1 0.0 1.8 2 0 0 2 2 2 1 lipin, N-terminal conserved region AF1Q PF15017.1 AIN95638.1 - 0.074 12.9 0.0 0.41 10.5 0.0 2.2 2 0 0 2 2 2 0 Drug resistance and apoptosis regulator Acid_phosphat_B PF03767.9 AIN95638.1 - 0.08 12.2 0.0 0.14 11.4 0.0 1.3 1 0 0 1 1 1 0 HAD superfamily, subfamily IIIB (Acid phosphatase) EF-hand_1 PF00036.27 AIN95640.1 - 0.055 12.8 0.0 0.1 11.9 0.0 1.4 1 0 0 1 1 1 0 EF hand EF-hand_7 PF13499.1 AIN95640.1 - 0.092 12.8 0.0 0.2 11.8 0.0 1.5 1 0 0 1 1 1 0 EF-hand domain pair EF-hand_6 PF13405.1 AIN95640.1 - 0.52 10.3 0.0 1.3 9.1 0.0 1.6 1 0 0 1 1 1 0 EF-hand domain Thymidylat_synt PF00303.14 AIN95641.1 - 1.9e-110 368.1 0.0 2.5e-110 367.7 0.0 1.1 1 0 0 1 1 1 1 Thymidylate synthase DHFR_1 PF00186.14 AIN95641.1 - 6.4e-24 84.3 0.0 4.8e-23 81.5 0.0 2.3 1 1 0 1 1 1 1 Dihydrofolate reductase Methyltransf_18 PF12847.2 AIN95642.1 - 2e-10 41.2 0.0 3.8e-10 40.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 AIN95642.1 - 2.2e-08 33.5 0.0 3.3e-08 33.0 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.9 AIN95642.1 - 6.8e-06 25.5 0.0 1.4e-05 24.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_16 PF10294.4 AIN95642.1 - 1.4e-05 24.6 0.0 2.2e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_26 PF13659.1 AIN95642.1 - 3.7e-05 23.7 0.0 6.8e-05 22.8 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain PRMT5 PF05185.11 AIN95642.1 - 0.00058 18.8 0.0 0.00074 18.5 0.0 1.1 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase Cons_hypoth95 PF03602.10 AIN95642.1 - 0.00078 18.8 0.0 0.0013 18.1 0.0 1.3 1 0 0 1 1 1 1 Conserved hypothetical protein 95 PCMT PF01135.14 AIN95642.1 - 0.00082 18.9 0.0 0.0013 18.2 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.1 AIN95642.1 - 0.001 18.6 0.0 0.0017 17.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Met_10 PF02475.11 AIN95642.1 - 0.0012 18.5 0.0 0.0018 17.9 0.0 1.3 1 0 0 1 1 1 1 Met-10+ like-protein RrnaAD PF00398.15 AIN95642.1 - 0.0026 16.8 0.0 0.0041 16.1 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase CMAS PF02353.15 AIN95642.1 - 0.0045 16.0 0.0 0.0067 15.5 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_11 PF08241.7 AIN95642.1 - 0.0055 17.1 0.0 0.016 15.6 0.0 1.8 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 AIN95642.1 - 0.015 15.7 0.0 0.037 14.4 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_25 PF13649.1 AIN95642.1 - 0.055 13.8 0.0 0.12 12.7 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_3 PF01596.12 AIN95642.1 - 0.15 11.0 0.0 0.24 10.4 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase Acyl-CoA_dh_1 PF00441.19 AIN95643.1 - 2.6e-48 163.9 3.3 3.9e-48 163.3 2.3 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 AIN95643.1 - 6.6e-29 100.7 0.3 2.1e-28 99.1 0.2 1.9 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.14 AIN95643.1 - 1.4e-23 82.1 0.6 4.6e-23 80.4 0.4 2.0 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 AIN95643.1 - 1.8e-21 76.7 1.7 3e-21 76.0 1.2 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain HpaB_N PF11794.3 AIN95643.1 - 0.012 15.0 0.7 0.071 12.4 0.5 2.2 1 1 0 1 1 1 0 4-hydroxyphenylacetate 3-hydroxylase N terminal Acyl-CoA_dh_1 PF00441.19 AIN95645.1 - 2.6e-48 163.9 3.3 3.9e-48 163.3 2.3 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 AIN95645.1 - 6.6e-29 100.7 0.3 2.1e-28 99.1 0.2 1.9 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.14 AIN95645.1 - 1.4e-23 82.1 0.6 4.6e-23 80.4 0.4 2.0 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 AIN95645.1 - 1.8e-21 76.7 1.7 3e-21 76.0 1.2 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain HpaB_N PF11794.3 AIN95645.1 - 0.012 15.0 0.7 0.071 12.4 0.5 2.2 1 1 0 1 1 1 0 4-hydroxyphenylacetate 3-hydroxylase N terminal PP2C PF00481.16 AIN95646.1 - 3.6e-25 88.8 0.3 1.3e-15 57.4 0.0 3.6 4 0 0 4 4 4 3 Protein phosphatase 2C PTH2 PF01981.11 AIN95647.1 - 1.8e-46 156.5 0.5 2.3e-46 156.2 0.3 1.1 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase PTH2 MscS_TM PF12794.2 AIN95647.1 - 0.15 10.6 1.3 0.22 10.0 0.9 1.1 1 0 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 Oxidored_FMN PF00724.15 AIN95649.1 - 9.7e-45 153.0 0.0 1.3e-44 152.6 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family NAD_binding_8 PF13450.1 AIN95649.1 - 7.6e-10 38.6 0.0 2.2e-09 37.2 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 AIN95649.1 - 1.6e-09 37.9 0.0 4.7e-09 36.4 0.0 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 AIN95649.1 - 6.7e-08 32.8 0.2 0.00061 19.9 0.1 2.6 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 AIN95649.1 - 9.1e-08 31.3 1.7 2e-07 30.2 1.2 1.8 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 AIN95649.1 - 1.4e-07 31.8 0.8 0.00043 20.6 0.4 3.6 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 AIN95649.1 - 1.6e-07 30.5 0.1 2.5e-07 29.9 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.9 AIN95649.1 - 9.8e-07 27.5 1.6 4.6e-06 25.3 0.1 2.5 2 1 1 3 3 3 1 HI0933-like protein FAD_oxidored PF12831.2 AIN95649.1 - 1.4e-06 27.6 1.0 4.2e-06 26.1 0.8 1.7 1 1 1 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.12 AIN95649.1 - 0.00035 19.7 0.0 0.00073 18.6 0.0 1.4 1 0 0 1 1 1 1 Thi4 family GIDA PF01134.17 AIN95649.1 - 0.00093 18.1 0.2 0.0014 17.5 0.2 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A Amino_oxidase PF01593.19 AIN95649.1 - 0.003 16.6 0.0 0.0047 16.0 0.0 1.2 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase 3HCDH_N PF02737.13 AIN95649.1 - 0.0064 16.1 0.0 0.032 13.8 0.0 2.1 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ApbA PF02558.11 AIN95649.1 - 0.0081 15.6 0.1 0.028 13.8 0.0 2.0 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA FAD_binding_3 PF01494.14 AIN95649.1 - 0.0096 15.0 0.1 0.016 14.2 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain NAD_Gly3P_dh_N PF01210.18 AIN95649.1 - 0.012 15.2 0.2 0.036 13.7 0.1 1.9 2 0 0 2 2 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_binding_10 PF13460.1 AIN95649.1 - 0.021 14.8 1.0 0.51 10.3 0.2 3.0 3 0 0 3 3 2 0 NADH(P)-binding FMO-like PF00743.14 AIN95649.1 - 0.05 11.8 0.1 1.7 6.7 0.0 2.1 2 0 0 2 2 2 0 Flavin-binding monooxygenase-like NAD_binding_7 PF13241.1 AIN95649.1 - 0.058 13.6 0.2 1 9.6 0.0 2.4 2 0 0 2 2 2 0 Putative NAD(P)-binding UDPG_MGDP_dh_N PF03721.9 AIN95649.1 - 0.06 12.7 0.0 0.12 11.7 0.0 1.6 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NAD_binding_9 PF13454.1 AIN95649.1 - 0.065 13.0 0.1 0.2 11.4 0.0 1.9 1 0 0 1 1 1 0 FAD-NAD(P)-binding ThiF PF00899.16 AIN95649.1 - 0.21 11.4 1.0 1.2 8.9 0.1 2.4 2 0 0 2 2 2 0 ThiF family TLD PF07534.11 AIN95650.1 - 6.2e-09 35.9 0.0 3.2e-05 23.9 0.0 3.2 3 0 0 3 3 3 3 TLD SIS PF01380.17 AIN95651.1 - 3.8e-50 168.8 0.4 1.7e-27 95.6 0.0 2.3 2 0 0 2 2 2 2 SIS domain GATase_6 PF13522.1 AIN95651.1 - 9.2e-18 64.4 0.0 1.9e-17 63.4 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_2 PF00310.16 AIN95651.1 - 2.7e-17 62.5 0.2 3.7e-11 42.3 0.0 2.3 2 0 0 2 2 2 2 Glutamine amidotransferases class-II GATase_7 PF13537.1 AIN95651.1 - 1.8e-11 43.8 0.0 4.3e-11 42.6 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_4 PF13230.1 AIN95651.1 - 9.8e-07 27.7 0.1 1.7e-06 26.9 0.1 1.3 1 0 0 1 1 1 1 Glutamine amidotransferases class-II SIS_2 PF13580.1 AIN95651.1 - 0.00074 19.2 0.0 0.13 11.9 0.0 2.7 3 0 0 3 3 3 1 SIS domain Mob1_phocein PF03637.12 AIN95652.1 - 8.2e-63 211.2 0.3 9.6e-63 210.9 0.2 1.0 1 0 0 1 1 1 1 Mob1/phocein family DUF3883 PF13020.1 AIN95653.1 - 3.5e-15 55.4 0.0 6.5e-15 54.6 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3883) LRR_8 PF13855.1 AIN95654.1 - 2.9e-21 74.9 11.2 4.5e-06 26.3 0.5 4.9 4 1 0 4 4 4 4 Leucine rich repeat LRR_4 PF12799.2 AIN95654.1 - 1.5e-20 72.3 12.4 6.9e-05 22.3 0.0 8.1 4 3 4 9 9 9 6 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 AIN95654.1 - 2.9e-08 32.6 18.0 7.7 6.9 0.0 11.1 12 1 1 13 13 13 2 Leucine Rich Repeat LRR_7 PF13504.1 AIN95654.1 - 3.3e-08 32.4 16.5 16 6.2 0.0 10.9 11 0 0 11 11 11 2 Leucine rich repeat DUF1399 PF07173.7 AIN95654.1 - 5.1e-05 23.5 0.5 0.1 12.8 0.0 3.5 2 1 1 3 3 3 2 Protein of unknown function (DUF1399) LRR_6 PF13516.1 AIN95654.1 - 0.39 10.9 15.6 77 3.8 0.3 8.7 9 1 1 10 10 10 0 Leucine Rich repeat WD40 PF00400.27 AIN95655.1 - 2.1e-08 33.7 0.1 3.6e-06 26.6 0.0 3.1 2 0 0 2 2 2 2 WD domain, G-beta repeat MHYT PF03707.11 AIN95656.1 - 3.3 7.9 11.0 0.53 10.4 2.6 2.5 2 1 0 2 2 2 0 Bacterial signalling protein N terminal repeat SET PF00856.23 AIN95657.1 - 2.9e-12 47.1 0.0 2.2e-09 37.8 0.0 2.4 2 0 0 2 2 2 2 SET domain zf-MYND PF01753.13 AIN95657.1 - 0.00029 20.6 10.5 0.00029 20.6 7.3 3.1 3 1 0 3 3 3 1 MYND finger G-patch PF01585.18 AIN95659.1 - 1.1e-11 44.2 0.7 1.7e-11 43.6 0.5 1.3 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.2 AIN95659.1 - 5.2e-07 29.4 0.5 1.1e-06 28.4 0.4 1.4 1 0 0 1 1 1 1 DExH-box splicing factor binding site Kinesin PF00225.18 AIN95660.1 - 2.7e-60 203.8 0.0 9.1e-60 202.1 0.0 1.7 1 1 0 1 1 1 1 Kinesin motor domain AAA_16 PF13191.1 AIN95660.1 - 0.0059 16.6 0.0 0.019 14.9 0.0 1.9 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 AIN95660.1 - 0.02 15.0 0.1 0.28 11.3 0.0 2.5 2 0 0 2 2 2 0 AAA domain T2SE PF00437.15 AIN95660.1 - 0.043 12.7 0.0 0.076 11.9 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein DUF2034 PF10356.4 AIN95660.1 - 0.064 12.4 0.2 0.12 11.5 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2034) DUF87 PF01935.12 AIN95660.1 - 0.092 12.5 0.0 0.18 11.6 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function DUF87 ATG16 PF08614.6 AIN95660.1 - 1.1 9.0 5.5 6 6.6 0.7 2.3 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) PLAC9 PF15205.1 AIN95661.1 - 0.12 12.6 0.4 1.7 9.0 0.1 2.8 2 0 0 2 2 2 0 Placenta-specific protein 9 Thioredoxin PF00085.15 AIN95662.1 - 8.7e-28 96.0 0.0 1e-27 95.8 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.1 AIN95662.1 - 2.5e-07 30.8 0.1 2.9e-06 27.4 0.0 2.0 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_7 PF13899.1 AIN95662.1 - 3.6e-07 30.0 0.0 5.3e-07 29.5 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_8 PF13905.1 AIN95662.1 - 0.00034 20.6 0.0 0.0042 17.1 0.0 2.1 1 1 1 2 2 2 1 Thioredoxin-like TraF PF13728.1 AIN95662.1 - 0.0054 16.2 0.0 0.0075 15.7 0.0 1.2 1 0 0 1 1 1 1 F plasmid transfer operon protein Thioredoxin_5 PF13743.1 AIN95662.1 - 0.051 13.1 0.0 5.9 6.4 0.0 2.1 2 0 0 2 2 2 0 Thioredoxin 2OG-FeII_Oxy_2 PF13532.1 AIN95663.1 - 9.7e-09 35.3 0.0 1.4e-07 31.5 0.0 2.1 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DeoC PF01791.4 AIN95664.1 - 2.8e-45 154.4 11.9 3.5e-45 154.1 8.2 1.0 1 0 0 1 1 1 1 DeoC/LacD family aldolase SNase PF00565.12 AIN95665.1 - 8.4e-16 58.1 0.0 1.2e-15 57.6 0.0 1.2 1 0 0 1 1 1 1 Staphylococcal nuclease homologue Ada_Zn_binding PF02805.11 AIN95665.1 - 0.12 12.0 0.0 0.31 10.6 0.0 1.7 1 0 0 1 1 1 0 Metal binding domain of Ada Tropomyosin_1 PF12718.2 AIN95666.1 - 0.0028 17.5 2.7 0.0028 17.5 1.8 4.1 3 1 1 4 4 4 1 Tropomyosin like DivIVA PF05103.8 AIN95666.1 - 0.017 15.1 3.5 0.017 15.1 2.4 5.0 3 2 1 4 4 4 0 DivIVA protein DUF3782 PF12644.2 AIN95666.1 - 0.096 12.4 14.8 0.33 10.7 0.3 3.8 3 1 0 3 3 3 0 Protein of unknown function (DUF3782) Toprim PF01751.17 AIN95666.1 - 0.11 12.4 0.7 0.3 11.0 0.1 2.1 2 0 0 2 2 2 0 Toprim domain Reo_sigmaC PF04582.7 AIN95666.1 - 0.67 9.0 15.5 1.4 8.0 0.3 3.3 2 1 2 4 4 4 0 Reovirus sigma C capsid protein ATG16 PF08614.6 AIN95666.1 - 9.4 6.0 48.0 0.24 11.1 2.2 4.2 2 1 1 4 4 4 0 Autophagy protein 16 (ATG16) DUF750 PF04721.12 AIN95668.1 - 0.12 12.3 0.0 0.28 11.1 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF750) PIG-X PF08320.7 AIN95669.1 - 0.017 14.3 0.1 0.38 10.0 0.0 2.5 2 1 0 2 2 2 0 PIG-X / PBN1 WD40 PF00400.27 AIN95670.1 - 9.5e-06 25.3 7.4 1.1e-05 25.0 0.1 4.1 6 0 0 6 6 6 1 WD domain, G-beta repeat DUF4379 PF14311.1 AIN95672.1 - 1.5e-24 85.5 26.0 5.6e-10 38.8 0.0 5.2 5 1 0 5 5 5 4 Domain of unknown function (DUF4379) SprT-like PF10263.4 AIN95672.1 - 0.013 15.1 8.4 0.34 10.5 0.1 3.3 3 0 0 3 3 3 0 SprT-like family HypA PF01155.14 AIN95672.1 - 0.072 12.7 17.5 1 9.0 0.3 4.4 5 0 0 5 5 5 0 Hydrogenase expression/synthesis hypA family NTF2 PF02136.15 AIN95674.1 - 3.1e-15 56.5 0.0 3.6e-15 56.3 0.0 1.0 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain Pkinase PF00069.20 AIN95675.1 - 6.9e-59 199.0 0.0 1.7e-37 128.9 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 AIN95675.1 - 7e-33 113.7 0.0 2.9e-23 82.2 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.18 AIN95675.1 - 6.5e-05 22.7 0.0 0.12 12.0 0.0 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kinase-like PF14531.1 AIN95675.1 - 0.00025 20.1 0.1 0.00062 18.8 0.0 1.6 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 AIN95675.1 - 0.017 14.2 0.0 0.035 13.1 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pox_ser-thr_kin PF05445.6 AIN95675.1 - 0.054 12.2 0.0 0.08 11.7 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Thioredoxin PF00085.15 AIN95676.1 - 1.1e-11 44.2 0.0 1.4e-11 43.9 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.1 AIN95676.1 - 0.1 12.7 0.1 0.26 11.4 0.1 1.5 1 1 0 1 1 1 0 Thioredoxin-like domain DUF1637 PF07847.7 AIN95681.1 - 4.5e-45 153.4 0.0 5.5e-45 153.2 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1637) CDO_I PF05995.7 AIN95681.1 - 0.0029 16.7 0.1 0.036 13.2 0.0 2.2 1 1 0 1 1 1 1 Cysteine dioxygenase type I Cupin_2 PF07883.6 AIN95681.1 - 0.074 12.5 0.0 4.9 6.7 0.0 2.9 3 0 0 3 3 3 0 Cupin domain FAD_binding_3 PF01494.14 AIN95682.1 - 7.2e-11 41.7 0.0 6.9e-10 38.4 0.0 2.3 1 1 0 1 1 1 1 FAD binding domain SE PF08491.5 AIN95682.1 - 0.03 13.1 0.0 0.048 12.4 0.0 1.3 1 0 0 1 1 1 0 Squalene epoxidase Flg_hook PF02120.11 AIN95682.1 - 0.059 13.0 0.1 0.25 11.0 0.0 2.0 2 0 0 2 2 2 0 Flagellar hook-length control protein FliK Hpt PF01627.18 AIN95682.1 - 0.27 11.2 2.3 0.82 9.7 0.0 2.6 3 0 0 3 3 3 0 Hpt domain DUF1632 PF07857.7 AIN95683.1 - 0.025 13.8 0.1 0.31 10.2 0.0 2.2 2 1 0 2 2 2 0 CEO family (DUF1632) Sugar_tr PF00083.19 AIN95683.1 - 0.053 12.0 4.3 3.5 6.0 0.0 2.4 1 1 2 3 3 3 0 Sugar (and other) transporter DUF2115 PF09888.4 AIN95683.1 - 0.057 13.5 0.1 6.8 6.7 0.1 2.3 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2115) DUF4191 PF13829.1 AIN95683.1 - 0.068 12.2 0.6 0.49 9.4 0.0 2.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4191) DUF3899 PF13038.1 AIN95683.1 - 0.15 12.2 7.1 4.6 7.4 0.1 3.5 2 2 1 3 3 3 0 Domain of unknown function (DUF3899) BT1 PF03092.11 AIN95684.1 - 9.1e-144 479.3 11.7 1.1e-143 479.1 8.1 1.0 1 0 0 1 1 1 1 BT1 family TAT_signal PF10518.4 AIN95684.1 - 1.3 9.2 5.8 1.5 9.0 0.3 3.4 3 0 0 3 3 3 0 TAT (twin-arginine translocation) pathway signal sequence MFS_1 PF07690.11 AIN95684.1 - 1.4 7.5 49.9 0.39 9.3 7.2 3.6 2 2 1 3 3 3 0 Major Facilitator Superfamily Coprogen_oxidas PF01218.13 AIN95685.1 - 3e-142 472.4 0.1 3.4e-142 472.3 0.1 1.0 1 0 0 1 1 1 1 Coproporphyrinogen III oxidase Flavodoxin_5 PF12724.2 AIN95686.1 - 4.1e-46 156.5 0.0 6.3e-46 155.9 0.0 1.3 1 0 0 1 1 1 1 Flavodoxin domain Flavodoxin_3 PF12641.2 AIN95686.1 - 3.7e-05 23.1 0.1 5.1e-05 22.7 0.0 1.2 1 0 0 1 1 1 1 Flavodoxin domain Flavodoxin_1 PF00258.20 AIN95686.1 - 0.054 13.4 0.0 0.082 12.9 0.0 1.3 1 0 0 1 1 1 0 Flavodoxin Cyt-b5 PF00173.23 AIN95687.1 - 0.001 18.8 0.0 0.0016 18.1 0.0 1.3 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Dispanin PF04505.7 AIN95687.1 - 0.13 11.8 0.0 0.19 11.2 0.0 1.3 1 0 0 1 1 1 0 Interferon-induced transmembrane protein DUF4252 PF14060.1 AIN95688.1 - 0.048 13.2 1.7 0.069 12.7 0.7 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4252) ThiF PF00899.16 AIN95689.1 - 1.2e-28 99.6 0.0 2.7e-28 98.4 0.0 1.6 1 0 0 1 1 1 1 ThiF family Shikimate_DH PF01488.15 AIN95689.1 - 2.5e-05 24.4 0.0 0.0005 20.1 0.0 2.2 1 1 1 2 2 2 1 Shikimate / quinate 5-dehydrogenase adh_short PF00106.20 AIN95689.1 - 0.031 14.1 2.2 3 7.7 0.1 2.4 2 0 0 2 2 2 0 short chain dehydrogenase 2-Hacid_dh_C PF02826.14 AIN95689.1 - 0.086 11.9 0.0 4 6.5 0.0 2.3 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Isy1 PF06246.7 AIN95690.1 - 3.1e-10 39.9 9.7 3.2e-08 33.3 6.7 2.5 1 1 0 1 1 1 1 Isy1-like splicing family DOT1 PF08123.8 AIN95691.1 - 8.5e-22 77.4 0.0 1.3e-21 76.8 0.0 1.2 1 0 0 1 1 1 1 Histone methylation protein DOT1 Methyltransf_18 PF12847.2 AIN95691.1 - 7.3e-06 26.5 0.0 1.3e-05 25.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 AIN95691.1 - 0.00023 21.1 0.0 0.00038 20.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 AIN95691.1 - 0.00029 21.1 0.0 0.00052 20.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 AIN95691.1 - 0.00039 20.0 0.0 0.00066 19.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 AIN95691.1 - 0.0011 19.4 0.0 0.0019 18.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.1 AIN95691.1 - 0.0032 17.1 0.0 0.0057 16.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 AIN95691.1 - 0.02 13.9 0.0 0.031 13.3 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase AdoMet_MTase PF07757.8 AIN95691.1 - 0.071 13.2 0.0 0.12 12.5 0.0 1.5 1 0 0 1 1 1 0 Predicted AdoMet-dependent methyltransferase Methyltransf_12 PF08242.7 AIN95691.1 - 0.078 13.4 0.0 0.13 12.7 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_23 PF13489.1 AIN95691.1 - 0.11 12.1 0.0 0.17 11.5 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Adaptin_N PF01602.15 AIN95693.1 - 5.6e-83 279.0 10.4 7.3e-83 278.6 7.2 1.1 1 0 0 1 1 1 1 Adaptin N terminal region HEAT_2 PF13646.1 AIN95693.1 - 0.00024 21.3 0.1 0.15 12.3 0.0 3.8 3 2 0 3 3 3 1 HEAT repeats Cnd1 PF12717.2 AIN95693.1 - 0.00041 20.2 3.6 0.47 10.2 0.0 2.7 1 1 1 2 2 2 2 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.17 AIN95693.1 - 0.0078 16.2 0.0 0.74 10.0 0.0 3.8 3 0 0 3 3 3 1 HEAT repeat FTSW_RODA_SPOVE PF01098.14 AIN95693.1 - 0.012 14.4 0.3 0.024 13.4 0.2 1.4 1 0 0 1 1 1 0 Cell cycle protein Cytochrom_C1 PF02167.10 AIN95694.1 - 3.2e-66 223.1 0.0 4e-66 222.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome C1 family S-methyl_trans PF02574.11 AIN95697.1 - 1.4e-90 303.7 0.1 2.9e-90 302.6 0.0 1.6 1 0 0 1 1 1 1 Homocysteine S-methyltransferase Met_synt_B12 PF02965.12 AIN95697.1 - 3.3e-64 215.9 0.1 1.7e-63 213.6 0.0 2.1 2 0 0 2 2 2 1 Vitamin B12 dependent methionine synthase, activation domain Pterin_bind PF00809.17 AIN95697.1 - 1.7e-35 122.2 0.1 5.9e-35 120.5 0.0 2.0 2 0 0 2 2 2 1 Pterin binding enzyme B12-binding_2 PF02607.12 AIN95697.1 - 9.9e-22 76.7 0.0 4.5e-21 74.6 0.0 2.3 2 0 0 2 2 2 1 B12 binding domain B12-binding PF02310.14 AIN95697.1 - 2e-21 76.1 0.2 7.2e-21 74.2 0.2 2.0 1 0 0 1 1 1 1 B12 binding domain Peptidase_A22B PF04258.8 AIN95697.1 - 0.014 14.8 0.0 0.022 14.1 0.0 1.2 1 0 0 1 1 1 0 Signal peptide peptidase Peptidase_M16_C PF05193.16 AIN95698.1 - 1.2e-22 80.5 0.0 1.7e-13 50.6 0.0 2.7 2 0 0 2 2 2 2 Peptidase M16 inactive domain M16C_assoc PF08367.6 AIN95698.1 - 4.6e-18 64.9 0.0 7.7e-18 64.2 0.0 1.4 1 0 0 1 1 1 1 Peptidase M16C associated Peptidase_M16 PF00675.15 AIN95698.1 - 5.6e-14 52.1 0.1 5.2e-11 42.5 0.0 2.7 2 0 0 2 2 2 2 Insulinase (Peptidase family M16) Shugoshin_C PF07557.6 AIN95698.1 - 0.0053 16.2 0.0 0.18 11.2 0.0 2.6 2 0 0 2 2 2 1 Shugoshin C terminus EF-hand_1 PF00036.27 AIN95699.1 - 3.2e-25 85.4 8.2 4.7e-07 28.6 0.0 4.9 5 0 0 5 5 5 4 EF hand EF-hand_8 PF13833.1 AIN95699.1 - 1.2e-23 82.4 0.6 9.1e-07 28.3 0.0 4.2 4 0 0 4 4 4 3 EF-hand domain pair EF-hand_6 PF13405.1 AIN95699.1 - 1.4e-23 80.6 1.4 8.5e-05 22.1 0.0 5.1 5 0 0 5 5 5 4 EF-hand domain EF-hand_7 PF13499.1 AIN95699.1 - 4.5e-22 77.9 1.6 5.2e-07 29.7 0.2 4.0 2 2 1 3 3 3 3 EF-hand domain pair EF-hand_5 PF13202.1 AIN95699.1 - 1.9e-16 58.5 8.8 7.4e-06 25.0 0.0 4.5 5 0 0 5 5 5 3 EF hand EF-hand_4 PF12763.2 AIN95699.1 - 2.1e-06 27.4 0.1 0.087 12.5 0.0 3.6 3 1 1 4 4 4 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.4 AIN95699.1 - 0.00019 21.4 0.0 0.0035 17.3 0.0 2.6 3 0 0 3 3 3 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_9 PF14658.1 AIN95699.1 - 0.00083 19.2 0.4 2.2 8.2 0.0 3.4 3 1 1 4 4 4 2 EF-hand domain TerB PF05099.8 AIN95699.1 - 0.12 12.0 0.0 1.8 8.2 0.0 2.4 3 0 0 3 3 3 0 Tellurite resistance protein TerB Sec7 PF01369.15 AIN95700.1 - 1.9e-36 125.5 0.0 4.5e-36 124.3 0.0 1.6 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.2 AIN95700.1 - 0.062 12.7 0.0 0.2 11.0 0.0 1.9 1 0 0 1 1 1 0 Guanine nucleotide exchange factor in Golgi transport N-terminal tRNA_Me_trans PF03054.11 AIN95701.1 - 1.3e-44 152.1 0.0 2.1e-32 112.1 0.0 3.4 3 0 0 3 3 3 3 tRNA methyl transferase NAD_synthase PF02540.12 AIN95701.1 - 0.04 12.8 0.1 0.068 12.0 0.1 1.3 1 0 0 1 1 1 0 NAD synthase Asn_synthase PF00733.16 AIN95701.1 - 0.046 13.1 0.0 0.074 12.5 0.0 1.3 1 0 0 1 1 1 0 Asparagine synthase DUF3259 PF11652.3 AIN95701.1 - 0.099 12.8 0.1 0.23 11.6 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3259) DUF1751 PF08551.5 AIN95702.1 - 6.9e-05 23.1 1.0 6.9e-05 23.1 0.7 2.6 2 2 1 3 3 3 1 Eukaryotic integral membrane protein (DUF1751) DUF747 PF05346.6 AIN95703.1 - 5.9e-59 199.7 1.5 8.4e-59 199.2 1.0 1.1 1 0 0 1 1 1 1 Eukaryotic membrane protein family PLAC8 PF04749.12 AIN95704.1 - 2.2e-06 28.1 27.9 4.3e-06 27.2 19.3 1.6 1 1 0 1 1 1 1 PLAC8 family Pkinase PF00069.20 AIN95705.1 - 2.8e-49 167.6 0.0 4.9e-49 166.8 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AIN95705.1 - 4.3e-32 111.2 0.0 9.9e-32 110.0 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 AIN95705.1 - 1.8e-06 27.1 0.0 3.8e-06 26.0 0.0 1.5 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 AIN95705.1 - 0.0075 16.0 0.1 0.0075 16.0 0.0 2.6 2 1 0 2 2 2 1 Phosphotransferase enzyme family MCR_C PF04609.7 AIN95705.1 - 0.087 11.6 1.5 0.14 10.9 1.1 1.3 1 0 0 1 1 1 0 Methyl-coenzyme M reductase operon protein C Pkinase PF00069.20 AIN95706.1 - 2.6e-50 171.0 0.0 9.2e-31 106.9 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 AIN95706.1 - 2.5e-35 121.8 0.0 3.5e-21 75.4 0.1 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 AIN95706.1 - 0.0015 17.5 0.0 0.39 9.6 0.0 2.3 2 0 0 2 2 2 2 Kinase-like PTPA PF03095.10 AIN95708.1 - 7.7e-105 350.3 0.0 9.2e-105 350.0 0.0 1.1 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein PLDc_2 PF13091.1 AIN95709.1 - 5e-09 35.9 0.0 3.9e-05 23.3 0.0 3.3 3 1 0 3 3 3 2 PLD-like domain PLDc PF00614.17 AIN95709.1 - 2.9e-06 26.9 0.3 2.6e-05 23.8 0.0 2.6 3 0 0 3 3 3 1 Phospholipase D Active site motif CIAPIN1 PF05093.8 AIN95712.1 - 4.4e-16 58.7 16.9 1.9e-14 53.5 11.7 2.1 1 1 0 1 1 1 1 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis Pkinase PF00069.20 AIN95714.1 - 1.3e-38 132.6 0.0 9.9e-15 54.3 0.0 3.4 3 1 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.12 AIN95714.1 - 8e-18 64.4 0.0 4.4e-12 45.6 0.0 2.6 2 1 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 AIN95714.1 - 0.00086 18.3 0.0 0.015 14.3 0.0 2.6 3 0 0 3 3 3 1 Kinase-like Kdo PF06293.9 AIN95714.1 - 0.5 9.3 0.0 0.87 8.6 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Homoserine_dh PF00742.14 AIN95715.1 - 9.1e-46 155.7 0.0 1.3e-45 155.3 0.0 1.1 1 0 0 1 1 1 1 Homoserine dehydrogenase Peptidase_M20 PF01546.23 AIN95716.1 - 1.9e-32 112.2 0.0 3.8e-32 111.3 0.0 1.5 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 AIN95716.1 - 3.4e-17 62.1 0.0 5.6e-17 61.5 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain HECT PF00632.20 AIN95717.1 - 3e-87 292.7 0.0 4.9e-87 292.0 0.0 1.4 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) XFP_C PF09363.5 AIN95717.1 - 0.087 12.2 0.0 0.23 10.8 0.0 1.7 1 0 0 1 1 1 0 XFP C-terminal domain ZZ PF00569.12 AIN95717.1 - 0.6 9.6 9.5 1.3 8.6 6.6 1.5 1 0 0 1 1 1 0 Zinc finger, ZZ type C1_3 PF07649.7 AIN95717.1 - 1.4 9.0 15.3 2.6 8.1 10.6 1.5 1 0 0 1 1 1 0 C1-like domain DUF972 PF06156.8 AIN95717.1 - 2.4 8.5 3.3 17 5.8 2.5 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF972) Seryl_tRNA_N PF02403.17 AIN95717.1 - 4.1 7.4 4.6 13 5.8 3.2 1.9 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain UPF0172 PF03665.8 AIN95718.1 - 5e-74 248.0 0.0 5.8e-74 247.8 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0172) LRR_4 PF12799.2 AIN95719.1 - 1.1e-05 24.9 0.1 0.0055 16.2 0.1 2.3 1 1 1 2 2 2 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 AIN95719.1 - 0.0011 18.6 0.1 0.0025 17.5 0.1 1.6 1 0 0 1 1 1 1 Leucine rich repeat LRR_1 PF00560.28 AIN95719.1 - 0.019 14.9 0.1 0.94 9.7 0.3 3.4 4 0 0 4 4 4 0 Leucine Rich Repeat BAF1_ABF1 PF04684.8 AIN95719.1 - 9.8 4.8 9.6 17 4.1 3.7 2.5 2 0 0 2 2 2 0 BAF1 / ABF1 chromatin reorganising factor Flagellar_rod PF05149.7 AIN95720.1 - 2.1e-08 33.7 15.2 2.1e-08 33.7 10.5 2.2 2 0 0 2 2 2 1 Paraflagellar rod protein DUF3275 PF11679.3 AIN95720.1 - 0.017 14.7 9.2 0.029 13.9 1.1 3.2 2 1 0 3 3 3 0 Protein of unknown function (DUF3275) IL6 PF00489.12 AIN95720.1 - 0.13 11.7 2.2 4.6 6.8 0.2 3.1 3 0 0 3 3 3 0 Interleukin-6/G-CSF/MGF family AAA_13 PF13166.1 AIN95720.1 - 0.35 9.2 1.1 1.2 7.4 0.4 1.9 2 0 0 2 2 2 0 AAA domain ABA_GPCR PF12430.3 AIN95722.1 - 1.5e-35 122.1 0.2 1.5e-35 122.1 0.2 1.7 2 0 0 2 2 2 1 Abscisic acid G-protein coupled receptor DUF3735 PF12537.3 AIN95722.1 - 2.3e-10 40.3 0.0 6.9e-10 38.8 0.0 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF3735) NUDIX PF00293.23 AIN95723.1 - 3.2e-07 30.0 0.0 7.4e-07 28.8 0.0 1.5 1 0 0 1 1 1 1 NUDIX domain DEAD PF00270.24 AIN95724.1 - 3.5e-42 143.7 0.0 1e-41 142.2 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 AIN95724.1 - 1.7e-25 88.6 0.2 1.4e-24 85.7 0.4 2.4 2 1 1 3 3 3 1 Helicase conserved C-terminal domain Helicase_C_2 PF13307.1 AIN95724.1 - 0.0049 16.8 0.0 0.0079 16.1 0.0 1.3 1 0 0 1 1 1 1 Helicase C-terminal domain ResIII PF04851.10 AIN95724.1 - 0.014 15.2 0.0 0.064 13.0 0.0 1.9 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit IgaA PF07095.6 AIN95725.1 - 0.28 8.9 0.1 0.39 8.4 0.1 1.1 1 0 0 1 1 1 0 Intracellular growth attenuator protein IgaA DUF1674 PF07896.7 AIN95726.1 - 1.6e-14 53.8 0.0 2.5e-14 53.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1674) zf-C3HC4_2 PF13923.1 AIN95727.1 - 8.4e-08 32.1 8.6 8.4e-08 32.1 5.9 2.5 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 AIN95727.1 - 5.5e-07 29.1 8.3 1.8e-06 27.4 5.7 2.0 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 AIN95727.1 - 2.6e-06 27.1 9.3 2.6e-06 27.1 6.4 2.9 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_4 PF15227.1 AIN95727.1 - 2e-05 24.3 7.0 5.6e-05 22.9 4.9 1.8 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.1 AIN95727.1 - 3.4e-05 23.4 7.7 3.4e-05 23.4 5.4 2.4 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 AIN95727.1 - 0.00027 20.5 7.5 0.00086 18.9 5.2 1.9 1 0 0 1 1 1 1 RING-type zinc-finger DUF1244 PF06844.6 AIN95727.1 - 0.066 13.0 0.3 0.2 11.5 0.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1244) U-box PF04564.10 AIN95727.1 - 0.094 12.6 0.9 0.9 9.5 0.0 3.0 4 1 1 5 5 5 0 U-box domain zf-Nse PF11789.3 AIN95727.1 - 8.1 6.0 11.7 0.39 10.2 3.3 2.5 3 0 0 3 3 3 0 Zinc-finger of the MIZ type in Nse subunit Rav1p_C PF12234.3 AIN95728.1 - 4.6e-37 127.4 0.5 3.6e-34 117.9 0.3 2.7 1 1 0 1 1 1 1 RAVE protein 1 C terminal WD40 PF00400.27 AIN95728.1 - 0.0012 18.6 2.4 0.48 10.3 0.1 4.0 3 0 0 3 3 3 2 WD domain, G-beta repeat EamA PF00892.15 AIN95730.1 - 4.5e-11 42.8 29.7 1.8e-09 37.7 1.5 2.8 3 0 0 3 3 3 2 EamA-like transporter family EmrE PF13536.1 AIN95730.1 - 1.2e-09 38.3 27.5 2.1e-08 34.3 0.4 3.7 3 1 1 4 4 4 2 Multidrug resistance efflux transporter UAA PF08449.6 AIN95730.1 - 3.6e-07 29.4 4.1 6.1e-07 28.6 2.8 1.3 1 0 0 1 1 1 1 UAA transporter family DUF914 PF06027.7 AIN95730.1 - 0.00091 18.1 11.0 0.00091 18.1 7.6 1.7 2 1 0 2 2 2 1 Eukaryotic protein of unknown function (DUF914) TPT PF03151.11 AIN95730.1 - 0.001 18.7 16.2 0.0085 15.7 0.0 3.3 3 1 0 3 3 3 2 Triose-phosphate Transporter family SIN1 PF05422.7 AIN95731.1 - 0.019 13.5 0.0 0.027 13.0 0.0 1.2 1 0 0 1 1 1 0 Stress-activated map kinase interacting protein 1 (SIN1) Osmo_MPGsynth PF09488.5 AIN95731.1 - 0.055 12.1 0.1 0.17 10.5 0.0 1.7 2 0 0 2 2 2 0 Mannosyl-3-phosphoglycerate synthase (osmo_MPGsynth) MaoC_dehydratas PF01575.14 AIN95733.1 - 2.7e-23 81.6 0.0 3.5e-23 81.2 0.0 1.1 1 0 0 1 1 1 1 MaoC like domain MaoC_dehydrat_N PF13452.1 AIN95733.1 - 4.1e-08 33.0 0.0 5.8e-08 32.5 0.0 1.2 1 0 0 1 1 1 1 N-terminal half of MaoC dehydratase 4HBT PF03061.17 AIN95733.1 - 0.089 12.9 0.0 0.21 11.7 0.0 1.6 2 0 0 2 2 2 0 Thioesterase superfamily MaoC_dehydratas PF01575.14 AIN95734.1 - 1.8e-24 85.4 0.0 2.8e-24 84.8 0.0 1.3 1 1 0 1 1 1 1 MaoC like domain MaoC_dehydrat_N PF13452.1 AIN95734.1 - 6.6e-11 42.1 0.0 2.5e-10 40.2 0.0 1.9 1 1 1 2 2 2 1 N-terminal half of MaoC dehydratase 4HBT PF03061.17 AIN95734.1 - 0.00021 21.3 0.0 0.00046 20.2 0.0 1.6 1 1 1 2 2 2 1 Thioesterase superfamily NOT2_3_5 PF04153.13 AIN95735.1 - 0.058 13.2 0.5 0.066 13.1 0.3 1.2 1 0 0 1 1 1 0 NOT2 / NOT3 / NOT5 family Acyl-CoA_dh_N PF02771.11 AIN95736.1 - 7.8e-11 42.5 0.0 2e-10 41.2 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.14 AIN95736.1 - 1.1e-06 28.0 0.4 2.5e-06 26.8 0.2 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain DUF663 PF04950.7 AIN95737.1 - 3.6e-80 269.1 0.0 8.3e-80 267.9 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF663) AARP2CN PF08142.7 AIN95737.1 - 1.8e-21 75.4 0.1 3.8e-21 74.4 0.1 1.5 1 0 0 1 1 1 1 AARP2CN (NUC121) domain DHC_N2 PF08393.8 AIN95739.1 - 1.4e-35 122.5 0.0 4.6e-35 120.8 0.0 1.9 2 0 0 2 2 2 1 Dynein heavy chain, N-terminal region 2 MBF1 PF08523.5 AIN95739.1 - 0.26 11.3 0.2 0.64 10.0 0.2 1.5 1 0 0 1 1 1 0 Multiprotein bridging factor 1 PBP1_TM PF14812.1 AIN95740.1 - 0.032 14.5 4.4 0.032 14.5 3.0 1.9 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal MCM2_N PF12619.3 AIN95740.1 - 0.24 11.3 13.0 1.1 9.2 5.7 2.2 2 0 0 2 2 2 0 Mini-chromosome maintenance protein 2 Nucleoplasmin PF03066.10 AIN95740.1 - 0.35 10.3 4.0 0.58 9.6 2.7 1.3 1 0 0 1 1 1 0 Nucleoplasmin Gly-zipper_OmpA PF13436.1 AIN95740.1 - 1.7 8.3 12.1 3.2 7.4 8.4 1.4 1 0 0 1 1 1 0 Glycine-zipper containing OmpA-like membrane domain DUF1180 PF06679.7 AIN95740.1 - 2.4 8.0 5.9 11 5.9 4.1 2.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1180) Ribosomal_L7Ae PF01248.21 AIN95741.1 - 3.9e-20 71.1 0.1 7.2e-20 70.3 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RNase_P_pop3 PF08228.6 AIN95741.1 - 4.7e-05 23.2 0.1 7.7e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 RNase P subunit Pop3 DUF2161 PF09929.4 AIN95741.1 - 0.13 12.2 0.5 0.25 11.2 0.4 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2161) Sec20 PF03908.8 AIN95742.1 - 0.00012 21.7 1.4 0.00043 19.9 0.6 2.1 1 1 1 2 2 2 1 Sec20 V-SNARE_C PF12352.3 AIN95742.1 - 0.0012 18.8 1.2 0.0039 17.2 0.9 1.8 1 0 0 1 1 1 1 Snare region anchored in the vesicle membrane C-terminus DUF2239 PF09998.4 AIN95742.1 - 0.0072 15.9 0.5 0.016 14.8 0.4 1.5 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2239) ADIP PF11559.3 AIN95742.1 - 0.43 10.4 9.2 0.14 12.0 4.0 1.9 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding CcmD PF04995.9 AIN95742.1 - 4.6 7.0 8.9 0.98 9.2 0.3 3.5 3 0 0 3 3 3 0 Heme exporter protein D (CcmD) DUF4407 PF14362.1 AIN95742.1 - 5 5.9 9.5 9 5.1 6.5 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Mito_carr PF00153.22 AIN95743.1 - 2.8e-34 116.6 4.6 6.4e-14 51.4 0.3 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein CP_ATPgrasp_1 PF04174.8 AIN95743.1 - 0.035 12.7 0.0 0.057 12.0 0.0 1.3 1 0 0 1 1 1 0 A circularly permuted ATPgrasp PFL PF02901.10 AIN95744.1 - 0.35 9.2 0.0 0.51 8.7 0.0 1.1 1 0 0 1 1 1 0 Pyruvate formate lyase DUF1615 PF07759.7 AIN95745.1 - 0.12 11.0 0.1 0.21 10.3 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1615) Ras PF00071.17 AIN95746.1 - 1.4e-54 183.8 0.0 1.6e-54 183.6 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 AIN95746.1 - 5.6e-14 52.6 0.0 8.7e-14 52.0 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 AIN95746.1 - 7.7e-10 38.2 0.0 9.9e-10 37.9 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 AIN95746.1 - 0.00018 20.9 0.0 0.0038 16.6 0.0 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 AIN95746.1 - 0.0023 17.8 0.0 0.0032 17.4 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 AIN95746.1 - 0.0023 17.0 0.0 0.0029 16.7 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MobB PF03205.9 AIN95748.1 - 2.9e-08 33.5 0.0 5.9e-08 32.5 0.0 1.4 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B Clp1 PF06807.9 AIN95748.1 - 0.00097 18.9 0.1 0.011 15.5 0.0 2.2 2 0 0 2 2 2 1 Pre-mRNA cleavage complex II protein Clp1 AAA_22 PF13401.1 AIN95748.1 - 0.017 15.3 0.2 0.05 13.7 0.0 1.9 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.17 AIN95748.1 - 0.095 12.8 0.0 0.19 11.9 0.0 1.4 1 0 0 1 1 1 0 RNA helicase Sel1 PF08238.7 AIN95749.1 - 5e-25 87.3 38.5 6.1e-07 29.8 0.0 9.3 9 0 0 9 9 9 7 Sel1 repeat JTB PF05439.7 AIN95749.1 - 0.25 11.1 0.1 0.52 10.1 0.1 1.4 1 0 0 1 1 1 0 Jumping translocation breakpoint protein (JTB) ETF_QO PF05187.8 AIN95750.1 - 3.7e-40 136.3 0.0 6.4e-40 135.5 0.0 1.3 1 0 0 1 1 1 1 Electron transfer flavoprotein-ubiquinone oxidoreductase DAO PF01266.19 AIN95750.1 - 3.1e-09 36.2 1.5 0.00047 19.1 0.6 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 AIN95750.1 - 3.5e-08 32.7 2.3 0.0012 17.7 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.1 AIN95750.1 - 5.4e-07 29.5 0.1 1.9e-06 27.8 0.1 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 AIN95750.1 - 5.5e-05 22.3 0.1 0.011 14.8 0.2 2.2 2 0 0 2 2 2 1 Thi4 family Pyr_redox_2 PF07992.9 AIN95750.1 - 0.0003 20.7 0.0 0.00085 19.2 0.0 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 AIN95750.1 - 0.00034 20.4 0.1 0.00064 19.5 0.0 1.5 1 0 0 1 1 1 1 FAD-NAD(P)-binding HI0933_like PF03486.9 AIN95750.1 - 0.0013 17.3 0.4 0.0019 16.7 0.3 1.2 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox PF00070.22 AIN95750.1 - 0.0013 19.0 0.2 0.29 11.5 0.2 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 AIN95750.1 - 0.0073 15.2 0.1 0.01 14.7 0.1 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Trp_halogenase PF04820.9 AIN95750.1 - 0.014 14.0 0.6 0.14 10.7 0.1 2.1 2 0 0 2 2 2 0 Tryptophan halogenase FAD_oxidored PF12831.2 AIN95750.1 - 0.018 14.1 0.2 0.029 13.4 0.1 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 AIN95750.1 - 0.021 14.8 0.2 0.038 14.0 0.1 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 AIN95750.1 - 0.068 12.2 0.9 0.094 11.7 0.1 1.6 2 0 0 2 2 2 0 FAD binding domain Fer4_7 PF12838.2 AIN95750.1 - 0.072 13.4 0.9 0.27 11.6 0.6 1.9 1 0 0 1 1 1 0 4Fe-4S dicluster domain Filament PF00038.16 AIN95753.1 - 0.00068 19.2 8.6 0.00068 19.2 6.0 3.4 2 1 0 3 3 3 1 Intermediate filament protein AAA_13 PF13166.1 AIN95753.1 - 0.017 13.6 22.9 0.041 12.3 7.2 2.8 1 1 1 2 2 2 0 AAA domain TBPIP PF07106.8 AIN95753.1 - 0.027 14.0 24.1 0.37 10.3 1.6 4.3 4 0 0 4 4 4 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Ycf54 PF10674.4 AIN95753.1 - 0.043 13.9 1.1 0.28 11.3 0.1 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2488) UMPH-1 PF05822.7 AIN95753.1 - 0.058 12.7 0.2 0.17 11.1 0.2 1.8 1 0 0 1 1 1 0 Pyrimidine 5'-nucleotidase (UMPH-1) WEMBL PF05701.6 AIN95753.1 - 0.072 11.5 41.0 0.17 10.3 9.7 2.6 2 1 0 2 2 2 0 Weak chloroplast movement under blue light RBD-FIP PF09457.5 AIN95753.1 - 0.13 12.0 0.1 0.13 12.0 0.1 4.1 5 0 0 5 5 5 0 FIP domain Reo_sigmaC PF04582.7 AIN95753.1 - 1 8.4 12.8 0.78 8.8 1.5 2.6 2 1 0 2 2 2 0 Reovirus sigma C capsid protein ERM PF00769.14 AIN95753.1 - 1.4 8.3 43.3 0.32 10.4 8.8 3.1 2 1 0 2 2 2 0 Ezrin/radixin/moesin family SOBP PF15279.1 AIN95753.1 - 2 8.7 22.1 5.1 7.3 10.1 2.2 1 1 1 2 2 2 0 Sine oculis-binding protein DUF3584 PF12128.3 AIN95753.1 - 9.7 3.3 43.3 2.4 5.3 9.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) E1-E2_ATPase PF00122.15 AIN95754.1 - 9.7e-54 181.8 0.9 1.8e-53 180.9 0.1 1.9 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 AIN95754.1 - 6.1e-41 139.9 1.9 1.4e-40 138.7 1.3 1.6 1 0 0 1 1 1 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 AIN95754.1 - 1.1e-22 81.5 0.0 1.4e-21 77.9 0.0 2.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 AIN95754.1 - 9.4e-13 47.4 0.0 1.8e-12 46.4 0.0 1.5 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus HAD PF12710.2 AIN95754.1 - 7.9e-11 42.4 0.0 2.3e-10 40.9 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 AIN95754.1 - 1.4e-10 40.9 0.0 3.3e-10 39.7 0.0 1.6 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 AIN95754.1 - 6.5e-06 25.8 0.0 0.0004 20.0 0.0 2.4 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase NfeD PF01957.13 AIN95754.1 - 0.42 10.7 3.5 0.83 9.7 0.0 2.8 3 0 0 3 3 3 0 NfeD-like C-terminal, partner-binding DUF3539 PF12058.3 AIN95755.1 - 0.016 14.9 0.0 0.11 12.3 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3539) E1-E2_ATPase PF00122.15 AIN95756.1 - 1.8e-53 180.9 0.1 1.8e-53 180.9 0.1 2.6 3 0 0 3 3 3 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 AIN95756.1 - 8.6e-41 139.4 5.2 1.9e-40 138.3 3.6 1.6 1 0 0 1 1 1 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 AIN95756.1 - 1.1e-22 81.4 0.0 1.4e-21 77.8 0.0 2.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 AIN95756.1 - 9.2e-13 47.4 0.0 1.9e-12 46.4 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus HAD PF12710.2 AIN95756.1 - 7.6e-11 42.5 0.0 2.4e-10 40.9 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 AIN95756.1 - 1.3e-10 41.0 0.0 3.4e-10 39.7 0.0 1.7 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 AIN95756.1 - 5.9e-06 26.0 0.0 0.0004 20.0 0.0 2.5 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF3325 PF11804.3 AIN95756.1 - 0.033 14.1 0.3 0.033 14.1 0.2 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3325) V-SNARE_C PF12352.3 AIN95758.1 - 1.2e-08 34.9 4.8 1.8e-08 34.3 3.3 1.2 1 0 0 1 1 1 1 Snare region anchored in the vesicle membrane C-terminus Synaptobrevin PF00957.16 AIN95758.1 - 0.031 13.8 1.4 0.043 13.4 0.3 1.7 1 1 1 2 2 2 0 Synaptobrevin Prominin PF05478.6 AIN95758.1 - 0.067 10.7 0.5 0.09 10.2 0.4 1.1 1 0 0 1 1 1 0 Prominin DUF720 PF05302.6 AIN95758.1 - 0.081 12.6 1.4 0.14 11.8 1.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF720) Ribosomal_S4 PF00163.14 AIN95759.1 - 7.5e-29 99.9 0.4 1.5e-28 98.9 0.3 1.5 1 0 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain S4 PF01479.20 AIN95759.1 - 6e-14 51.2 0.4 1.3e-13 50.1 0.3 1.6 1 0 0 1 1 1 1 S4 domain Pkinase PF00069.20 AIN95760.1 - 9.9e-43 146.1 0.0 1.1e-26 93.5 0.0 4.0 3 1 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.12 AIN95760.1 - 3e-22 78.9 0.0 9.3e-16 57.6 0.0 2.9 3 1 0 3 3 3 2 Protein tyrosine kinase NTP_transf_2 PF01909.18 AIN95761.1 - 0.0047 17.2 0.0 0.0098 16.1 0.0 1.5 1 0 0 1 1 1 1 Nucleotidyltransferase domain Inhibitor_Mig-6 PF11555.3 AIN95761.1 - 0.0075 16.6 0.0 0.025 14.9 0.0 1.9 1 0 0 1 1 1 1 EGFR receptor inhibitor Mig-6 PAP_assoc PF03828.14 AIN95761.1 - 0.0081 16.0 0.0 0.032 14.1 0.0 1.9 2 0 0 2 2 2 1 Cid1 family poly A polymerase EF-hand_1 PF00036.27 AIN95762.1 - 1.7e-26 89.4 8.9 5.1e-09 34.8 0.5 4.4 5 0 0 5 5 5 3 EF hand EF-hand_6 PF13405.1 AIN95762.1 - 3.2e-22 76.3 3.3 5.3e-09 35.2 0.1 4.5 5 0 0 5 5 5 3 EF-hand domain EF-hand_7 PF13499.1 AIN95762.1 - 6.2e-22 77.5 4.2 8.5e-12 45.0 1.5 2.8 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_8 PF13833.1 AIN95762.1 - 2.5e-18 65.4 11.9 4.6e-13 48.5 1.1 3.9 2 2 2 4 4 4 3 EF-hand domain pair EF-hand_5 PF13202.1 AIN95762.1 - 5e-17 60.3 10.6 4.7e-06 25.7 0.1 4.2 4 0 0 4 4 4 3 EF hand EF-hand_9 PF14658.1 AIN95762.1 - 8.9e-10 38.3 0.0 3.6e-05 23.5 0.0 2.4 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.2 AIN95762.1 - 4.2e-06 26.4 0.8 0.013 15.2 0.0 2.6 2 1 1 3 3 3 2 Cytoskeletal-regulatory complex EF hand Ribosomal_L11 PF00298.14 AIN95762.1 - 0.14 12.3 0.0 77 3.5 0.0 3.2 3 0 0 3 3 3 0 Ribosomal protein L11, RNA binding domain HEAT_2 PF13646.1 AIN95764.1 - 7.1e-12 45.4 24.4 9.7e-05 22.5 0.0 8.6 5 4 2 7 7 7 3 HEAT repeats HEAT PF02985.17 AIN95764.1 - 6.2e-09 35.1 22.3 0.035 14.1 0.4 10.3 11 0 0 11 11 11 3 HEAT repeat CLASP_N PF12348.3 AIN95764.1 - 4.9e-06 26.0 0.1 0.032 13.6 0.0 3.2 3 0 0 3 3 3 2 CLASP N terminal HEAT_EZ PF13513.1 AIN95764.1 - 8.1e-06 26.1 44.3 0.0053 17.2 1.3 12.3 9 4 3 12 12 12 4 HEAT-like repeat Vac14_Fab1_bd PF12755.2 AIN95764.1 - 0.026 14.9 0.1 0.77 10.1 0.0 3.6 3 0 0 3 3 3 0 Vacuolar 14 Fab1-binding region DUF3437 PF11919.3 AIN95764.1 - 0.026 14.2 2.4 0.07 12.8 0.1 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF3437) IBN_N PF03810.14 AIN95764.1 - 0.039 13.8 0.0 0.21 11.4 0.0 2.3 2 0 0 2 2 2 0 Importin-beta N-terminal domain Arm PF00514.18 AIN95764.1 - 0.058 13.2 3.7 2 8.3 0.0 5.1 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat Arm_2 PF04826.8 AIN95764.1 - 0.2 10.7 0.0 0.52 9.3 0.0 1.6 1 0 0 1 1 1 0 Armadillo-like MCD PF05292.6 AIN95765.1 - 1.9e-57 194.6 0.0 1.3e-36 126.0 0.0 2.9 1 1 1 2 2 2 2 Malonyl-CoA decarboxylase (MCD) PPI_Ypi1 PF07491.6 AIN95767.1 - 2.1e-16 59.2 2.2 3.6e-16 58.5 1.5 1.4 1 0 0 1 1 1 1 Protein phosphatase inhibitor DUF2763 PF10961.3 AIN95767.1 - 0.028 14.7 0.2 0.044 14.1 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2763) DnaJ PF00226.26 AIN95768.1 - 9.7e-07 28.4 0.0 2e-06 27.4 0.0 1.5 1 0 0 1 1 1 1 DnaJ domain His_Phos_1 PF00300.17 AIN95769.1 - 4.4e-28 98.3 0.1 9.7e-28 97.2 0.0 1.6 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) 6PF2K PF01591.13 AIN95769.1 - 6.7e-15 54.7 0.3 1.8e-10 40.3 0.0 3.3 3 0 0 3 3 3 3 6-phosphofructo-2-kinase AAA_33 PF13671.1 AIN95769.1 - 0.00021 21.2 0.7 0.062 13.1 0.0 3.1 4 0 0 4 4 4 2 AAA domain AAA_17 PF13207.1 AIN95769.1 - 0.13 13.1 0.0 0.41 11.4 0.0 1.9 1 0 0 1 1 1 0 AAA domain DnaJ PF00226.26 AIN95770.1 - 6.9e-07 28.9 0.0 1.4e-06 27.8 0.0 1.5 1 0 0 1 1 1 1 DnaJ domain DnaJ PF00226.26 AIN95771.1 - 8.2e-10 38.2 0.1 1.8e-09 37.1 0.0 1.6 1 0 0 1 1 1 1 DnaJ domain Pam16 PF03656.8 AIN95771.1 - 0.014 15.1 0.0 0.033 13.9 0.0 1.5 1 0 0 1 1 1 0 Pam16 TFIIB PF00382.14 AIN95771.1 - 0.09 12.6 0.0 0.6 9.9 0.0 2.3 2 0 0 2 2 2 0 Transcription factor TFIIB repeat RRM_6 PF14259.1 AIN95773.1 - 0.00012 21.9 0.0 0.00022 21.1 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 AIN95773.1 - 0.0023 17.5 0.0 0.0043 16.6 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PGM_PMM_I PF02878.11 AIN95774.1 - 2.2e-13 49.8 0.0 1.4e-09 37.5 0.0 2.5 2 0 0 2 2 2 2 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_IV PF00408.15 AIN95774.1 - 9.4e-10 38.3 0.1 2.2e-09 37.1 0.1 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain PGM_PMM_II PF02879.11 AIN95774.1 - 2.2e-08 34.3 0.0 1.5e-07 31.6 0.0 2.3 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_III PF02880.11 AIN95774.1 - 0.012 15.6 0.1 0.024 14.6 0.1 1.5 1 0 0 1 1 1 0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III UQ_con PF00179.21 AIN95776.1 - 4e-38 129.9 0.0 5.5e-38 129.5 0.0 1.3 1 1 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 AIN95776.1 - 0.051 13.3 0.0 0.069 12.8 0.0 1.2 1 0 0 1 1 1 0 Prokaryotic E2 family B RRM_5 PF13893.1 AIN95778.1 - 2.4e-06 27.3 0.1 0.004 16.9 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 AIN95778.1 - 0.0057 16.6 0.0 0.45 10.5 0.0 2.4 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 AIN95778.1 - 0.042 13.4 0.1 3.9 7.1 0.0 2.5 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Pkinase PF00069.20 AIN95779.1 - 3e-55 187.1 0.0 6.4e-55 186.0 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 AIN95779.1 - 6e-36 123.8 0.0 4.1e-35 121.1 0.0 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase PX PF00787.19 AIN95779.1 - 0.0012 18.6 0.0 0.0024 17.6 0.0 1.5 1 0 0 1 1 1 1 PX domain Kinase-like PF14531.1 AIN95779.1 - 0.039 12.9 0.0 0.07 12.0 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Glyco_transf_10 PF00852.14 AIN95780.1 - 4.4e-19 68.2 0.4 1e-13 50.6 0.2 2.8 2 1 0 2 2 2 2 Glycosyltransferase family 10 (fucosyltransferase) HrpB1_HrpK PF09613.5 AIN95780.1 - 0.0056 16.1 0.6 0.014 14.9 0.4 1.6 1 0 0 1 1 1 1 Bacterial type III secretion protein (HrpB1_HrpK) Pkinase PF00069.20 AIN95782.1 - 1.4e-76 257.0 0.0 1.6e-76 256.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AIN95782.1 - 1.8e-39 135.3 0.0 2.2e-39 135.1 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 AIN95782.1 - 6.9e-11 41.6 0.0 1.5e-09 37.2 0.0 2.0 1 1 1 2 2 2 1 Kinase-like Kdo PF06293.9 AIN95782.1 - 0.00063 18.8 0.1 0.001 18.2 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 AIN95782.1 - 0.001 18.4 0.1 0.0017 17.7 0.1 1.3 1 0 0 1 1 1 1 RIO1 family APH PF01636.18 AIN95782.1 - 0.0028 17.4 0.1 0.21 11.2 0.0 2.2 2 0 0 2 2 2 1 Phosphotransferase enzyme family DUF3608 PF12257.3 AIN95783.1 - 4.3e-18 65.1 0.6 5.9e-11 41.7 0.0 3.2 3 0 0 3 3 3 3 Protein of unknown function (DUF3608) DUF2738 PF10927.3 AIN95783.1 - 1.7 7.6 0.0 2.7 6.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2738) Radial_spoke PF04712.7 AIN95784.1 - 2.2e-07 30.0 0.5 0.00054 18.8 0.0 2.7 2 1 0 2 2 2 2 Radial spokehead-like protein Myc_N PF01056.13 AIN95784.1 - 0.00092 18.4 2.0 0.0013 18.0 1.4 1.1 1 0 0 1 1 1 1 Myc amino-terminal region CENP-B_dimeris PF09026.5 AIN95784.1 - 0.0011 19.2 2.0 0.0018 18.4 1.4 1.3 1 0 0 1 1 1 1 Centromere protein B dimerisation domain BNR PF02012.15 AIN95784.1 - 0.05 13.4 0.1 0.12 12.2 0.1 1.7 1 0 0 1 1 1 0 BNR/Asp-box repeat PBP1_TM PF14812.1 AIN95784.1 - 0.058 13.6 1.3 0.096 12.9 0.9 1.3 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Sigma70_ner PF04546.8 AIN95784.1 - 0.059 12.9 3.6 0.08 12.5 2.5 1.2 1 0 0 1 1 1 0 Sigma-70, non-essential region Nucleoplasmin PF03066.10 AIN95784.1 - 0.094 12.2 3.8 0.15 11.6 2.6 1.3 1 0 0 1 1 1 0 Nucleoplasmin UBN_AB PF14075.1 AIN95784.1 - 0.29 10.7 1.5 0.45 10.1 1.0 1.2 1 0 0 1 1 1 0 Ubinuclein conserved middle domain NOA36 PF06524.7 AIN95784.1 - 0.57 9.3 3.8 0.88 8.7 2.6 1.2 1 0 0 1 1 1 0 NOA36 protein Nucleo_P87 PF07267.6 AIN95784.1 - 0.67 8.5 2.1 0.88 8.1 1.4 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Ribosomal_60s PF00428.14 AIN95784.1 - 2.2 8.7 11.8 4 7.9 8.2 1.3 1 0 0 1 1 1 0 60s Acidic ribosomal protein DUF3437 PF11919.3 AIN95785.1 - 7.8e-21 73.5 0.0 4.9e-20 71.0 0.0 2.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3437) Nucleoplasmin PF03066.10 AIN95789.1 - 0.0014 18.2 0.1 0.0015 18.0 0.1 1.2 1 0 0 1 1 1 1 Nucleoplasmin Nucleoplasmin PF03066.10 AIN95790.1 - 3.1e-06 26.7 0.2 3.1e-06 26.7 0.2 3.7 2 1 1 3 3 3 1 Nucleoplasmin Nucleoplasmin PF03066.10 AIN95791.1 - 0.69 9.4 0.0 0.69 9.4 0.0 4.4 2 1 1 3 3 3 0 Nucleoplasmin DUF59 PF01883.14 AIN95792.1 - 3.6e-08 33.2 0.0 1e-07 31.7 0.0 1.8 1 1 0 1 1 1 1 Domain of unknown function DUF59 Glyco_hydro_1 PF00232.13 AIN95792.1 - 0.075 11.2 0.0 0.075 11.2 0.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 1 PIF1 PF05970.9 AIN95793.1 - 2.3e-42 145.2 0.0 1.1e-33 116.7 0.0 2.8 3 0 0 3 3 3 2 PIF1-like helicase Herpes_Helicase PF02689.9 AIN95793.1 - 8.8e-11 40.3 3.2 5.5e-07 27.7 0.1 2.1 2 0 0 2 2 2 2 Helicase AAA_30 PF13604.1 AIN95793.1 - 3.4e-10 39.8 0.0 7.5e-10 38.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 AIN95793.1 - 1.7e-06 28.1 0.0 3.6e-06 27.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.13 AIN95793.1 - 2.8e-05 23.7 0.0 0.0003 20.3 0.0 2.7 2 1 0 2 2 2 1 Viral (Superfamily 1) RNA helicase AAA_19 PF13245.1 AIN95793.1 - 0.00016 21.3 0.5 0.00046 19.8 0.3 1.8 1 0 0 1 1 1 1 Part of AAA domain AAA_11 PF13086.1 AIN95793.1 - 0.00047 19.8 0.1 1.1 8.7 0.0 3.4 2 1 1 3 3 3 1 AAA domain T2SE PF00437.15 AIN95793.1 - 0.0023 16.8 0.1 0.0047 15.8 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_5 PF07728.9 AIN95793.1 - 0.0026 17.4 0.0 0.0081 15.8 0.0 1.9 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) UvrD_C_2 PF13538.1 AIN95793.1 - 0.0029 17.7 0.0 0.012 15.7 0.0 2.0 1 1 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_16 PF13191.1 AIN95793.1 - 0.016 15.1 0.1 0.035 14.1 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain Mg_chelatase PF01078.16 AIN95793.1 - 0.023 13.8 0.0 0.043 12.9 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI ABC_tran PF00005.22 AIN95793.1 - 0.07 13.4 0.1 0.14 12.4 0.1 1.4 1 0 0 1 1 1 0 ABC transporter NACHT PF05729.7 AIN95793.1 - 0.14 11.7 0.0 0.28 10.8 0.0 1.5 1 0 0 1 1 1 0 NACHT domain DUF2075 PF09848.4 AIN95793.1 - 0.22 10.4 0.0 0.32 9.9 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) NTPase_1 PF03266.10 AIN95793.1 - 0.34 10.6 0.1 4.3 7.0 0.1 2.2 2 0 0 2 2 2 0 NTPase Rotamase PF00639.16 AIN95794.1 - 1.6e-21 76.8 0.0 1.8e-21 76.6 0.0 1.0 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_3 PF13616.1 AIN95794.1 - 2.6e-14 53.4 0.0 3e-14 53.2 0.0 1.1 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_2 PF13145.1 AIN95794.1 - 0.017 15.7 0.0 0.021 15.4 0.0 1.1 1 0 0 1 1 1 0 PPIC-type PPIASE domain Sel1 PF08238.7 AIN95796.1 - 7.5e-05 23.2 7.6 0.14 12.8 2.7 4.1 3 2 0 3 3 3 2 Sel1 repeat E1-E2_ATPase PF00122.15 AIN95797.1 - 6.5e-24 84.2 0.4 3.5e-23 81.8 0.0 2.4 3 1 0 3 3 3 1 E1-E2 ATPase HAD PF12710.2 AIN95797.1 - 1.1e-20 74.5 0.0 2.3e-20 73.5 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 AIN95797.1 - 2.6e-18 67.2 0.0 2.1e-17 64.2 0.0 2.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 AIN95797.1 - 0.00017 21.4 0.0 0.00041 20.2 0.0 1.6 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 AIN95797.1 - 0.026 14.0 0.3 0.071 12.6 0.1 1.8 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase Dpy-30 PF05186.8 AIN95798.1 - 8e-12 44.4 0.0 1.3e-11 43.7 0.0 1.4 1 0 0 1 1 1 1 Dpy-30 motif BPL_LplA_LipB PF03099.14 AIN95799.1 - 7.5e-19 67.9 0.0 1.8e-18 66.7 0.0 1.6 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family zf-C2H2 PF00096.21 AIN95800.1 - 1.1e-07 31.7 7.8 0.00028 21.0 0.6 2.5 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 AIN95800.1 - 5.2e-05 23.2 8.6 0.072 13.4 0.5 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_6 PF13912.1 AIN95800.1 - 0.00021 21.0 4.0 0.08 12.8 0.2 2.5 2 0 0 2 2 2 2 C2H2-type zinc finger zf-Di19 PF05605.7 AIN95800.1 - 0.0015 18.5 1.4 0.17 12.0 0.2 2.5 2 0 0 2 2 2 1 Drought induced 19 protein (Di19), zinc-binding zf-met2 PF12907.2 AIN95800.1 - 0.0055 16.6 1.7 0.0055 16.6 1.1 2.4 2 0 0 2 2 2 1 Zinc-binding zf-H2C2_2 PF13465.1 AIN95800.1 - 0.016 15.5 3.9 2.7 8.4 0.1 2.8 2 0 0 2 2 2 0 Zinc-finger double domain zf-met PF12874.2 AIN95800.1 - 0.029 14.5 1.1 0.029 14.5 0.8 2.4 2 0 0 2 2 2 0 Zinc-finger of C2H2 type DUF629 PF04780.7 AIN95800.1 - 0.034 12.6 0.8 1.2 7.5 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF629) A2L_zn_ribbon PF08792.5 AIN95800.1 - 0.04 13.3 1.0 0.04 13.3 0.7 2.2 2 0 0 2 2 2 0 A2L zinc ribbon domain zf-trcl PF13451.1 AIN95800.1 - 0.069 12.7 1.2 2.3 7.9 0.0 2.4 2 0 0 2 2 2 0 Probable zinc-binding domain zf-C2H2_2 PF12756.2 AIN95800.1 - 0.07 13.2 5.6 0.54 10.3 0.2 2.3 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) CpXC PF14353.1 AIN95800.1 - 0.071 13.0 2.5 5.5 6.9 0.1 2.2 2 0 0 2 2 2 0 CpXC protein zinc-ribbons_6 PF07191.7 AIN95800.1 - 0.14 11.9 2.5 4.3 7.2 0.2 2.3 2 0 0 2 2 2 0 zinc-ribbons zinc_ribbon_4 PF13717.1 AIN95800.1 - 0.15 11.7 1.8 14 5.4 0.1 2.6 2 0 0 2 2 2 0 zinc-ribbon domain TFIIS_C PF01096.13 AIN95800.1 - 0.17 11.5 4.2 2.8 7.6 0.2 2.6 2 0 0 2 2 2 0 Transcription factor S-II (TFIIS) DUF3505 PF12013.3 AIN95800.1 - 0.2 11.9 1.5 0.96 9.7 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3505) C1_4 PF07975.7 AIN95800.1 - 0.38 10.7 3.7 3.5 7.7 0.0 2.4 2 0 0 2 2 2 0 TFIIH C1-like domain zf-C2H2_jaz PF12171.3 AIN95800.1 - 0.73 10.0 6.7 0.37 11.0 0.6 2.7 3 0 0 3 3 2 0 Zinc-finger double-stranded RNA-binding zinc_ribbon_5 PF13719.1 AIN95800.1 - 2.8 7.6 6.7 12 5.6 0.1 2.7 3 0 0 3 3 2 0 zinc-ribbon domain DUF3235 PF11574.3 AIN95800.1 - 4.9 7.4 6.9 12 6.2 0.1 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3235) DUF1601 PF07671.6 AIN95801.1 - 0.16 11.6 0.1 0.16 11.6 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1601) APG6 PF04111.7 AIN95801.1 - 0.52 9.3 24.2 1.8 7.5 7.6 2.5 1 1 0 2 2 2 0 Autophagy protein Apg6 V_ATPase_I PF01496.14 AIN95801.1 - 7.6 4.2 9.6 12 3.5 6.6 1.4 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family FA_desaturase PF00487.19 AIN95802.1 - 5.9e-44 150.4 23.7 8.5e-44 149.9 16.4 1.2 1 0 0 1 1 1 1 Fatty acid desaturase ECM11 PF15463.1 AIN95803.1 - 0.0025 18.0 0.4 0.005 17.1 0.3 1.5 1 0 0 1 1 1 1 Extracellular mutant protein 11 BCNT PF07572.7 AIN95803.1 - 0.12 12.3 1.7 0.18 11.7 0.4 1.8 2 0 0 2 2 2 0 Bucentaur or craniofacial development HemX PF04375.9 AIN95804.1 - 0.0025 16.4 1.9 0.16 10.5 0.1 2.3 2 0 0 2 2 2 2 HemX VWA_2 PF13519.1 AIN95805.1 - 4.2e-09 36.7 0.3 7.7e-09 35.8 0.2 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain UIM PF02809.15 AIN95805.1 - 0.0028 17.0 4.5 0.0028 17.0 3.1 3.5 3 0 0 3 3 3 2 Ubiquitin interaction motif IU_nuc_hydro PF01156.14 AIN95805.1 - 0.0046 16.2 0.3 0.0084 15.3 0.2 1.4 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase Ssl1 PF04056.9 AIN95805.1 - 0.032 13.8 0.0 0.046 13.3 0.0 1.2 1 0 0 1 1 1 0 Ssl1-like Miro PF08477.8 AIN95806.1 - 0.00096 19.6 0.0 0.0017 18.7 0.0 1.5 1 0 0 1 1 1 1 Miro-like protein EF-hand_1 PF00036.27 AIN95806.1 - 0.11 11.8 0.2 0.54 9.6 0.0 2.3 2 0 0 2 2 2 0 EF hand PMSR PF01625.16 AIN95807.1 - 1.7e-53 180.7 0.2 2.1e-53 180.3 0.1 1.1 1 0 0 1 1 1 1 Peptide methionine sulfoxide reductase Chorein_N PF12624.2 AIN95808.1 - 9.4e-05 21.9 0.0 0.00036 20.0 0.0 2.0 1 0 0 1 1 1 1 N-terminal region of Chorein, a TM vesicle-mediated sorter Aa_trans PF01490.13 AIN95809.1 - 4.7e-59 199.9 22.2 5.4e-59 199.7 15.4 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.8 AIN95809.1 - 7.4e-10 38.1 8.2 7.4e-10 38.1 5.7 2.1 2 0 0 2 2 2 1 Tryptophan/tyrosine permease family Galactosyl_T PF01762.16 AIN95810.1 - 0.00091 18.8 0.1 0.0013 18.3 0.1 1.2 1 0 0 1 1 1 1 Galactosyltransferase SMC_N PF02463.14 AIN95811.1 - 3.3e-60 203.0 1.5 4.3e-60 202.6 1.1 1.1 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 AIN95811.1 - 4.4e-25 87.9 0.1 1.9e-24 85.9 0.0 2.2 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.1 AIN95811.1 - 4.1e-15 56.5 0.0 6.9e-07 29.5 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_23 PF13476.1 AIN95811.1 - 1.8e-14 54.5 4.3 1.8e-14 54.5 2.9 4.9 2 2 1 3 3 3 1 AAA domain AAA_15 PF13175.1 AIN95811.1 - 1.3e-07 31.0 6.5 0.0034 16.4 4.3 3.0 2 1 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.1 AIN95811.1 - 6.5e-05 22.3 0.0 0.00015 21.1 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain ABC_tran PF00005.22 AIN95811.1 - 0.4 10.9 20.1 0.15 12.3 0.3 5.2 3 2 0 3 3 3 0 ABC transporter DASH_Dam1 PF08653.5 AIN95811.1 - 8.1 6.3 8.2 21 4.9 0.0 4.2 5 0 0 5 5 5 0 DASH complex subunit Dam1 Synaptobrevin PF00957.16 AIN95813.1 - 1.2e-30 104.9 4.7 2.2e-30 104.0 3.2 1.5 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.1 AIN95813.1 - 0.0073 15.8 0.0 0.014 14.9 0.0 1.4 1 0 0 1 1 1 1 Regulated-SNARE-like domain His_Phos_1 PF00300.17 AIN95816.1 - 1.4e-29 103.2 0.0 1.6e-29 103.0 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) ASCH PF04266.9 AIN95817.1 - 3.6e-16 59.4 0.0 1.1e-15 57.8 0.0 1.9 1 0 0 1 1 1 1 ASCH domain zf-C2HC5 PF06221.8 AIN95817.1 - 9.9e-12 44.4 8.1 2e-11 43.4 5.6 1.5 1 0 0 1 1 1 1 Putative zinc finger motif, C2HC5-type Peptidase_C12 PF01088.16 AIN95817.1 - 0.1 11.7 0.4 0.73 8.9 0.0 2.1 2 0 0 2 2 2 0 Ubiquitin carboxyl-terminal hydrolase, family 1 DEAD PF00270.24 AIN95818.1 - 1.7e-33 115.5 0.0 3e-33 114.7 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 AIN95818.1 - 1.8e-19 69.3 0.0 4.6e-19 68.0 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_22 PF13401.1 AIN95818.1 - 0.00015 21.9 0.0 0.00072 19.7 0.0 2.2 2 0 0 2 2 2 1 AAA domain ResIII PF04851.10 AIN95818.1 - 0.00057 19.7 0.0 0.0015 18.3 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SecA_DEAD PF07517.9 AIN95818.1 - 0.017 14.4 0.0 0.27 10.4 0.0 2.2 2 0 0 2 2 2 0 SecA DEAD-like domain SNF2_N PF00176.18 AIN95818.1 - 0.082 11.6 0.0 0.13 10.9 0.0 1.3 1 0 0 1 1 1 0 SNF2 family N-terminal domain Adaptin_N PF01602.15 AIN95819.1 - 2.2e-80 270.4 0.6 3.4e-80 269.8 0.1 1.5 2 0 0 2 2 2 1 Adaptin N terminal region HEAT_2 PF13646.1 AIN95819.1 - 7e-06 26.2 0.3 0.087 13.1 0.2 4.0 2 1 1 3 3 3 2 HEAT repeats HEAT PF02985.17 AIN95819.1 - 0.00031 20.5 6.2 0.28 11.3 0.1 4.9 4 0 0 4 4 4 1 HEAT repeat Cnd1 PF12717.2 AIN95819.1 - 0.0015 18.3 0.3 0.91 9.3 0.0 2.6 1 1 0 2 2 2 2 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.2 AIN95819.1 - 0.0069 16.7 0.1 0.16 12.3 0.0 2.5 2 0 0 2 2 2 1 Vacuolar 14 Fab1-binding region Arm_2 PF04826.8 AIN95819.1 - 0.0087 15.2 0.1 0.019 14.0 0.1 1.5 1 0 0 1 1 1 1 Armadillo-like DUF2435 PF10363.4 AIN95819.1 - 0.013 15.3 0.1 0.042 13.7 0.1 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2435) DSPc PF00782.15 AIN95820.1 - 1e-27 96.2 0.1 2.2e-27 95.2 0.0 1.6 1 1 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase2 PF03162.8 AIN95820.1 - 0.012 15.0 0.0 1.6 8.0 0.0 2.8 3 0 0 3 3 3 0 Tyrosine phosphatase family Init_tRNA_PT PF04179.7 AIN95820.1 - 0.031 13.1 0.0 0.044 12.6 0.0 1.1 1 0 0 1 1 1 0 Initiator tRNA phosphoribosyl transferase Y_phosphatase PF00102.22 AIN95820.1 - 0.048 12.9 0.0 0.073 12.3 0.0 1.3 1 0 0 1 1 1 0 Protein-tyrosine phosphatase PTPlike_phytase PF14566.1 AIN95820.1 - 0.064 13.3 0.0 0.13 12.3 0.0 1.5 1 0 0 1 1 1 0 Inositol hexakisphosphate BLOC1_2 PF10046.4 AIN95821.1 - 0.0059 16.7 2.6 0.0059 16.7 1.8 3.0 2 1 1 3 3 3 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 SCP-1 PF05483.7 AIN95821.1 - 0.015 13.1 10.1 0.024 12.4 7.0 1.2 1 0 0 1 1 1 0 Synaptonemal complex protein 1 (SCP-1) CENP-Q PF13094.1 AIN95821.1 - 0.029 14.4 13.8 0.081 12.9 9.5 1.8 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit Phage_GP20 PF06810.6 AIN95821.1 - 0.11 11.9 9.1 0.2 11.1 6.3 1.4 1 0 0 1 1 1 0 Phage minor structural protein GP20 TBPIP PF07106.8 AIN95821.1 - 0.17 11.4 11.0 0.33 10.4 7.0 1.9 1 1 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) NPV_P10 PF05531.7 AIN95821.1 - 0.18 12.0 4.8 6.4 7.1 0.2 2.9 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein Filament PF00038.16 AIN95821.1 - 0.2 11.0 19.4 0.47 9.8 11.6 2.2 1 1 1 2 2 2 0 Intermediate filament protein DUF1664 PF07889.7 AIN95821.1 - 1.3 8.8 9.0 0.84 9.4 1.2 2.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Vfa1 PF08432.5 AIN95821.1 - 1.9 8.5 7.1 3.8 7.5 5.0 1.4 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 DUF342 PF03961.8 AIN95821.1 - 2.6 6.3 5.3 3.8 5.8 3.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF342) AAA_13 PF13166.1 AIN95821.1 - 3.2 6.0 8.2 4.9 5.4 5.7 1.2 1 0 0 1 1 1 0 AAA domain V_ATPase_I PF01496.14 AIN95821.1 - 3.7 5.2 6.7 5.3 4.7 4.7 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family IncA PF04156.9 AIN95821.1 - 4.8 6.7 23.3 1.2 8.7 5.6 2.7 2 1 1 3 3 3 0 IncA protein DUF972 PF06156.8 AIN95821.1 - 5 7.5 12.0 9.3 6.6 1.3 2.8 1 1 2 3 3 3 0 Protein of unknown function (DUF972) FYVE_2 PF02318.11 AIN95823.1 - 0.12 12.2 9.4 0.24 11.3 6.5 1.3 1 0 0 1 1 1 0 FYVE-type zinc finger ERCC4 PF02732.10 AIN95824.1 - 3.4e-14 52.8 0.0 8.5e-14 51.5 0.0 1.7 1 0 0 1 1 1 1 ERCC4 domain PIG-H PF10181.4 AIN95825.1 - 1.3e-14 53.6 0.1 2e-14 52.9 0.1 1.3 1 0 0 1 1 1 1 GPI-GlcNAc transferase complex, PIG-H component LRR_4 PF12799.2 AIN95827.1 - 4e-08 32.7 9.5 0.0033 17.0 0.0 5.9 5 2 1 6 6 6 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 AIN95827.1 - 1.7e-07 30.9 4.6 0.0084 15.8 0.0 4.4 3 1 0 3 3 3 3 Leucine rich repeat LRR_1 PF00560.28 AIN95827.1 - 2.7 8.3 18.8 2.4 8.5 0.1 6.8 8 1 0 8 8 8 0 Leucine Rich Repeat Hexapep PF00132.19 AIN95828.1 - 8e-17 59.9 7.6 1.3e-05 24.4 1.6 3.3 2 1 1 3 3 3 3 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 AIN95828.1 - 0.0026 17.2 0.5 0.0026 17.2 0.4 2.7 3 1 0 3 3 3 1 Hexapeptide repeat of succinyl-transferase Exo_endo_phos PF03372.18 AIN95830.1 - 3.7e-18 66.3 0.0 6.9e-18 65.4 0.0 1.6 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.1 AIN95830.1 - 0.09 12.3 0.0 0.25 10.9 0.0 1.8 1 0 0 1 1 1 0 Endonuclease-reverse transcriptase ThiF PF00899.16 AIN95832.1 - 3.1e-29 101.5 0.0 9.6e-29 99.9 0.0 1.8 1 1 0 1 1 1 1 ThiF family UBACT PF02134.16 AIN95832.1 - 8.5e-23 79.7 0.4 2.3e-22 78.3 0.3 1.8 1 0 0 1 1 1 1 Repeat in ubiquitin-activating (UBA) protein UAE_UbL PF14732.1 AIN95832.1 - 4.4e-20 71.5 0.0 9.3e-20 70.5 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain UBA_e1_thiolCys PF10585.4 AIN95832.1 - 1.3e-16 59.7 3.8 9.8e-16 56.8 1.6 2.4 2 0 0 2 2 2 1 Ubiquitin-activating enzyme active site Shikimate_DH PF01488.15 AIN95832.1 - 0.024 14.7 0.0 0.063 13.3 0.0 1.7 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase ABC1 PF03109.11 AIN95833.1 - 1.7e-27 95.7 0.0 6.6e-27 93.8 0.0 2.0 2 0 0 2 2 2 1 ABC1 family APH PF01636.18 AIN95833.1 - 0.00075 19.2 2.5 0.0032 17.2 0.0 2.9 3 1 0 3 3 3 1 Phosphotransferase enzyme family Ribosomal_L9_N PF01281.14 AIN95834.1 - 2.9e-06 26.3 0.0 5.1e-06 25.6 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L9, N-terminal domain HAMP PF00672.20 AIN95835.1 - 0.021 15.0 0.0 0.16 12.1 0.0 2.3 2 1 1 3 3 3 0 HAMP domain DUF4591 PF15261.1 AIN95836.1 - 8.7e-06 26.0 10.2 0.004 17.4 0.0 3.5 2 1 0 2 2 2 2 Domain of unknown function (DUF4591) Ribosomal_L2_C PF03947.13 AIN95838.1 - 2.3e-18 66.2 0.1 3.9e-18 65.4 0.1 1.3 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Sod_Fe_C PF02777.13 AIN95839.1 - 1.4e-37 127.7 0.2 2.5e-37 126.9 0.2 1.4 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.17 AIN95839.1 - 1.5e-20 73.2 0.8 3.2e-20 72.1 0.4 1.7 1 1 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain Isochorismatase PF00857.15 AIN95840.1 - 4.6e-13 49.4 0.0 1.6e-12 47.6 0.0 1.8 1 1 0 1 1 1 1 Isochorismatase family Isochorismatase PF00857.15 AIN95841.1 - 6.1e-09 36.0 0.1 6.1e-09 36.0 0.1 2.2 3 0 0 3 3 3 1 Isochorismatase family Isochorismatase PF00857.15 AIN95842.1 - 1.6e-11 44.4 0.0 5.8e-11 42.6 0.0 1.8 1 1 0 1 1 1 1 Isochorismatase family zf-Tim10_DDP PF02953.10 AIN95843.1 - 1.6e-17 62.5 0.3 2.2e-17 62.0 0.2 1.2 1 0 0 1 1 1 1 Tim10/DDP family zinc finger DUF842 PF05811.8 AIN95843.1 - 0.0039 16.6 0.2 0.006 16.0 0.2 1.3 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF842) FWWh PF14922.1 AIN95848.1 - 3.1e-05 23.5 0.0 0.00017 21.0 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function APG6 PF04111.7 AIN95850.1 - 9.5e-17 61.0 0.0 1.1e-05 24.6 0.0 4.3 4 0 0 4 4 4 4 Autophagy protein Apg6 Baculo_gp64 PF03273.8 AIN95850.1 - 0.83 7.7 0.1 1.2 7.2 0.0 1.1 1 0 0 1 1 1 0 Baculovirus gp64 envelope glycoprotein family WD40 PF00400.27 AIN95851.1 - 1.3e-37 126.3 19.8 2.1e-10 40.0 0.0 11.0 10 1 0 10 10 10 7 WD domain, G-beta repeat PQQ_2 PF13360.1 AIN95851.1 - 3.4e-08 33.2 0.8 0.0015 18.0 0.1 4.4 3 1 1 4 4 4 2 PQQ-like domain BBS2_Mid PF14783.1 AIN95851.1 - 0.0015 18.3 0.3 2.3 8.0 0.0 4.7 6 1 0 7 7 7 1 Ciliary BBSome complex subunit 2, middle region eIF2A PF08662.6 AIN95851.1 - 0.043 13.5 0.0 5.4 6.6 0.0 3.2 3 1 0 3 3 3 0 Eukaryotic translation initiation factor eIF2A Utp8 PF10395.4 AIN95851.1 - 0.74 8.0 0.0 20 3.3 0.0 2.1 2 0 0 2 2 2 0 Utp8 family Peptidase_S24 PF00717.18 AIN95855.1 - 6.8e-10 38.4 0.1 1.2e-09 37.6 0.0 1.5 1 0 0 1 1 1 1 Peptidase S24-like Rad60-SLD PF11976.3 AIN95857.1 - 2.3e-25 88.0 0.1 2.8e-25 87.7 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.18 AIN95857.1 - 1.7e-09 36.9 0.0 2.1e-09 36.6 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin family TUG-UBL1 PF11470.3 AIN95857.1 - 0.13 12.2 0.0 0.17 11.7 0.0 1.2 1 0 0 1 1 1 0 GLUT4 regulating protein TUG FdhE PF04216.7 AIN95858.1 - 0.34 10.5 1.9 0.33 10.6 0.1 1.7 2 0 0 2 2 2 0 Protein involved in formate dehydrogenase formation Metal_resist PF13801.1 AIN95858.1 - 5.1 7.0 10.4 0.43 10.5 1.3 2.6 2 1 0 2 2 2 0 Heavy-metal resistance Pribosyl_synth PF14572.1 AIN95861.1 - 5.9e-21 75.0 4.9 9.3e-21 74.4 0.7 2.4 2 0 0 2 2 2 1 Phosphoribosyl synthetase-associated domain Pribosyltran_N PF13793.1 AIN95861.1 - 1.1e-18 67.0 0.6 1.5e-17 63.4 0.0 2.5 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase SPX PF03105.14 AIN95861.1 - 2.8e-06 27.3 0.5 5e-05 23.2 0.1 2.1 2 0 0 2 2 2 1 SPX domain Pkinase PF00069.20 AIN95862.1 - 1.6e-07 30.7 0.0 0.016 14.3 0.0 2.6 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 AIN95862.1 - 3.8e-07 29.4 0.0 0.014 14.5 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Kelch_1 PF01344.20 AIN95862.1 - 0.021 14.3 0.0 3.5 7.2 0.0 3.2 2 0 0 2 2 2 0 Kelch motif PEPCK PF00821.13 AIN95862.1 - 1.2 7.2 0.0 1.8 6.6 0.0 1.1 1 0 0 1 1 1 0 Phosphoenolpyruvate carboxykinase Pkinase PF00069.20 AIN95863.1 - 3.2e-38 131.3 0.0 3e-14 52.8 0.0 3.8 4 0 0 4 4 4 3 Protein kinase domain Pkinase_Tyr PF07714.12 AIN95863.1 - 1.8e-16 59.9 0.0 3.9e-05 22.8 0.0 3.3 3 0 0 3 3 3 3 Protein tyrosine kinase Baculo_11_kDa PF06143.6 AIN95863.1 - 2.4 7.5 2.8 5.5 6.4 1.9 1.5 1 0 0 1 1 1 0 Baculovirus 11 kDa family Complex1_LYR PF05347.10 AIN95864.1 - 0.00061 19.5 0.7 0.0067 16.1 0.6 2.4 2 0 0 2 2 2 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 AIN95864.1 - 0.0033 17.6 0.7 0.011 15.8 0.5 1.9 1 0 0 1 1 1 1 Complex1_LYR-like CMAS PF02353.15 AIN95865.1 - 3.4e-74 249.3 0.6 4.9e-74 248.8 0.4 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.1 AIN95865.1 - 4.9e-13 49.1 0.0 1e-12 48.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 AIN95865.1 - 9.8e-12 45.2 0.0 2.5e-11 43.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 AIN95865.1 - 3.6e-10 40.0 0.0 9.6e-10 38.7 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 AIN95865.1 - 5.3e-09 36.4 0.0 2e-08 34.5 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 AIN95865.1 - 3e-08 34.2 0.0 7.4e-08 32.9 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 AIN95865.1 - 2e-06 27.4 0.0 3.6e-06 26.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 AIN95865.1 - 4.9e-06 26.0 0.0 1.7e-05 24.2 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_26 PF13659.1 AIN95865.1 - 5.5e-05 23.1 0.0 0.00028 20.9 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain MetW PF07021.7 AIN95865.1 - 0.001 18.5 0.0 0.0019 17.6 0.0 1.4 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW NodS PF05401.6 AIN95865.1 - 0.0013 18.1 0.0 0.0021 17.4 0.0 1.3 1 0 0 1 1 1 1 Nodulation protein S (NodS) Methyltransf_32 PF13679.1 AIN95865.1 - 0.0014 18.3 0.0 0.0024 17.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain TehB PF03848.9 AIN95865.1 - 0.0047 16.1 0.0 0.0087 15.2 0.0 1.3 1 0 0 1 1 1 1 Tellurite resistance protein TehB PCMT PF01135.14 AIN95865.1 - 0.006 16.1 0.0 0.011 15.2 0.0 1.4 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) FtsJ PF01728.14 AIN95865.1 - 0.022 14.7 0.0 0.04 13.9 0.0 1.4 1 0 0 1 1 1 0 FtsJ-like methyltransferase RrnaAD PF00398.15 AIN95865.1 - 0.027 13.5 0.0 0.062 12.3 0.0 1.5 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase eIF-5_eIF-2B PF01873.12 AIN95866.1 - 4e-24 84.6 0.8 6.8e-24 83.9 0.5 1.4 1 0 0 1 1 1 1 Domain found in IF2B/IF5 Cytochrom_c3_2 PF14537.1 AIN95866.1 - 0.056 13.7 0.6 0.26 11.6 0.2 2.2 3 0 0 3 3 3 0 Cytochrome c3 CDC37_N PF03234.9 AIN95866.1 - 0.071 13.4 2.0 0.18 12.0 1.3 1.7 1 1 0 1 1 1 0 Cdc37 N terminal kinase binding Img2 PF05046.9 AIN95867.1 - 0.0003 20.9 0.0 0.00052 20.1 0.0 1.4 1 0 0 1 1 1 1 Mitochondrial large subunit ribosomal protein (Img2) CK1gamma_C PF12605.3 AIN95868.1 - 0.044 14.3 0.8 0.072 13.6 0.5 1.4 1 0 0 1 1 1 0 Casein kinase 1 gamma C terminal CobS PF02654.10 AIN95868.1 - 0.11 12.0 0.2 0.21 11.1 0.1 1.3 1 0 0 1 1 1 0 Cobalamin-5-phosphate synthase DUF4233 PF14017.1 AIN95868.1 - 8.1 6.4 8.0 1 9.3 0.2 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF4233) Mtp PF03821.11 AIN95869.1 - 0.041 13.2 0.0 0.062 12.6 0.0 1.3 1 0 0 1 1 1 0 Golgi 4-transmembrane spanning transporter Amastin PF07344.6 AIN95870.1 - 3.1e-53 179.5 15.8 3.7e-53 179.3 11.0 1.0 1 0 0 1 1 1 1 Amastin surface glycoprotein DUF4199 PF13858.1 AIN95871.1 - 0.057 13.3 0.5 0.068 13.0 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4199) Prominin PF05478.6 AIN95871.1 - 0.072 10.6 0.0 0.083 10.4 0.0 1.1 1 0 0 1 1 1 0 Prominin PsaA_PsaB PF00223.14 AIN95871.1 - 0.077 11.0 0.1 0.084 10.9 0.0 1.0 1 0 0 1 1 1 0 Photosystem I psaA/psaB protein DUF1279 PF06916.8 AIN95871.1 - 0.082 13.2 0.1 0.11 12.7 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1279) TMEM52 PF14979.1 AIN95871.1 - 0.12 12.2 0.0 0.19 11.6 0.0 1.3 1 0 0 1 1 1 0 Transmembrane 52 DUF2839 PF10999.3 AIN95871.1 - 2.9 7.9 4.7 0.46 10.5 0.6 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2839) DUF4110 PF13422.1 AIN95872.1 - 0.00072 19.3 0.2 0.0041 16.9 0.0 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF4110) Amastin PF07344.6 AIN95874.1 - 1.3e-05 24.8 4.6 1.3e-05 24.8 3.2 1.9 2 0 0 2 2 2 1 Amastin surface glycoprotein DnaJ PF00226.26 AIN95875.1 - 1.3e-18 66.4 1.2 2e-18 65.8 0.9 1.3 1 0 0 1 1 1 1 DnaJ domain Acetyltransf_11 PF13720.1 AIN95875.1 - 0.12 12.5 0.4 0.95 9.7 0.1 2.2 2 0 0 2 2 2 0 Udp N-acetylglucosamine O-acyltransferase; Domain 2 Amastin PF07344.6 AIN95876.1 - 7.3e-52 175.0 9.9 8.7e-52 174.8 6.8 1.1 1 0 0 1 1 1 1 Amastin surface glycoprotein Claudin_2 PF13903.1 AIN95876.1 - 0.31 10.6 19.4 0.013 15.1 7.1 2.1 1 1 1 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction AAA_16 PF13191.1 AIN95877.1 - 3.2e-05 24.0 0.0 4.8e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA_33 PF13671.1 AIN95877.1 - 0.00034 20.5 0.2 0.00065 19.5 0.0 1.6 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 AIN95877.1 - 0.0019 18.3 0.0 0.0038 17.3 0.0 1.7 2 1 0 2 2 2 1 AAA domain Adeno_IVa2 PF02456.10 AIN95877.1 - 0.0034 16.0 0.0 0.0044 15.7 0.0 1.1 1 0 0 1 1 1 1 Adenovirus IVa2 protein AAA PF00004.24 AIN95877.1 - 0.0038 17.4 0.0 0.0067 16.6 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Zeta_toxin PF06414.7 AIN95877.1 - 0.0049 15.9 0.0 0.011 14.8 0.0 1.5 1 1 0 1 1 1 1 Zeta toxin AAA_17 PF13207.1 AIN95877.1 - 0.007 17.1 0.0 0.017 15.9 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 AIN95877.1 - 0.015 15.6 0.0 0.026 14.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain Arch_ATPase PF01637.13 AIN95877.1 - 0.019 14.6 0.0 0.029 14.0 0.0 1.3 1 0 0 1 1 1 0 Archaeal ATPase AAA_19 PF13245.1 AIN95877.1 - 0.033 13.9 0.4 0.23 11.2 0.0 2.4 2 0 0 2 2 2 0 Part of AAA domain AAA_14 PF13173.1 AIN95877.1 - 0.036 13.9 0.0 0.06 13.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain Rad17 PF03215.10 AIN95877.1 - 0.04 12.5 0.0 0.053 12.1 0.0 1.1 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein AAA_28 PF13521.1 AIN95877.1 - 0.066 13.1 0.1 0.17 11.8 0.0 1.7 3 0 0 3 3 2 0 AAA domain SMC_N PF02463.14 AIN95877.1 - 0.067 12.4 0.0 0.093 11.9 0.0 1.2 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain ABC_tran PF00005.22 AIN95877.1 - 0.071 13.4 0.0 0.15 12.3 0.0 1.4 1 1 0 1 1 1 0 ABC transporter Viral_helicase1 PF01443.13 AIN95877.1 - 0.12 11.9 0.0 0.17 11.4 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase DUF815 PF05673.8 AIN95877.1 - 0.15 10.9 0.0 0.2 10.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_23 PF13476.1 AIN95877.1 - 0.18 12.1 0.0 0.24 11.7 0.0 1.1 1 0 0 1 1 1 0 AAA domain Amastin PF07344.6 AIN95878.1 - 2.6e-55 186.2 6.4 3e-55 186.0 4.4 1.0 1 0 0 1 1 1 1 Amastin surface glycoprotein Claudin_2 PF13903.1 AIN95878.1 - 5.4e-06 26.2 6.7 9e-06 25.4 4.6 1.3 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction DUF2165 PF09933.4 AIN95878.1 - 0.054 13.2 0.4 0.11 12.1 0.3 1.5 1 0 0 1 1 1 0 Predicted small integral membrane protein (DUF2165) MARVEL PF01284.18 AIN95878.1 - 5.6 6.7 12.9 32 4.3 8.9 2.1 1 1 0 1 1 1 0 Membrane-associating domain Amastin PF07344.6 AIN95879.1 - 9.7e-54 181.1 13.7 1.1e-53 180.9 9.5 1.0 1 0 0 1 1 1 1 Amastin surface glycoprotein Claudin_2 PF13903.1 AIN95879.1 - 0.21 11.2 21.6 0.34 10.5 13.8 1.9 1 1 1 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction PAP1 PF08601.5 AIN95880.1 - 0.054 13.1 0.9 0.093 12.3 0.1 1.7 1 1 0 2 2 2 0 Transcription factor PAP1 GRP PF07172.6 AIN95880.1 - 2.1 8.8 6.6 0.21 12.0 0.2 2.2 2 0 0 2 2 2 0 Glycine rich protein family Toxin_44 PF15523.1 AIN95881.1 - 0.0093 15.8 1.5 0.031 14.1 1.0 1.9 1 0 0 1 1 1 1 Putative toxin 44 CotJB PF12652.2 AIN95881.1 - 0.063 13.3 4.4 2.2 8.4 1.6 3.2 2 1 1 3 3 3 0 CotJB protein TRIQK PF15168.1 AIN95881.1 - 0.063 13.2 0.2 0.13 12.2 0.1 1.5 1 0 0 1 1 1 0 Triple QxxK/R motif-containing protein family SET PF00856.23 AIN95882.1 - 5.8e-10 39.7 0.0 1.6e-08 35.0 0.0 2.9 1 1 0 1 1 1 1 SET domain DNA_pol_B_thumb PF14791.1 AIN95883.1 - 8.5e-20 70.2 0.0 2.4e-19 68.7 0.0 1.9 1 1 0 1 1 1 1 DNA polymerase beta thumb DNA_pol_B_palm PF14792.1 AIN95883.1 - 4.8e-18 65.2 0.0 1.1e-17 64.0 0.0 1.6 1 0 0 1 1 1 1 DNA polymerase beta palm DNA_pol_lambd_f PF10391.4 AIN95883.1 - 3e-15 55.4 0.2 1e-14 53.7 0.0 2.1 2 0 0 2 2 2 1 Fingers domain of DNA polymerase lambda HHH_8 PF14716.1 AIN95883.1 - 2.5e-14 53.1 0.3 2.3e-12 46.9 0.1 2.6 2 0 0 2 2 2 1 Helix-hairpin-helix domain HHH_5 PF14520.1 AIN95883.1 - 0.00037 20.6 0.6 0.025 14.7 0.1 2.5 1 1 1 2 2 2 2 Helix-hairpin-helix domain HHH_3 PF12836.2 AIN95883.1 - 0.045 13.7 0.1 3.7 7.5 0.0 2.7 2 0 0 2 2 2 0 Helix-hairpin-helix motif DNA_pol_B_palm PF14792.1 AIN95884.1 - 5.6e-25 87.5 0.0 1.2e-24 86.5 0.0 1.6 1 0 0 1 1 1 1 DNA polymerase beta palm DNA_pol_B_thumb PF14791.1 AIN95884.1 - 3.5e-18 65.0 0.8 5.1e-09 35.6 0.0 3.7 4 0 0 4 4 4 2 DNA polymerase beta thumb DNA_pol_lambd_f PF10391.4 AIN95884.1 - 3.8e-09 35.9 0.0 0.00058 19.3 0.0 2.6 2 0 0 2 2 2 2 Fingers domain of DNA polymerase lambda HHH_8 PF14716.1 AIN95884.1 - 0.0022 18.1 0.4 4.3 7.5 0.0 3.9 4 0 0 4 4 4 1 Helix-hairpin-helix domain NTP_transf_2 PF01909.18 AIN95884.1 - 0.011 15.9 0.0 0.025 14.8 0.0 1.5 1 0 0 1 1 1 0 Nucleotidyltransferase domain Lactamase_B_2 PF12706.2 AIN95885.1 - 1.5e-17 63.7 0.0 6.8e-09 35.5 0.0 3.3 2 1 0 2 2 2 2 Beta-lactamase superfamily domain Lactamase_B_4 PF13691.1 AIN95885.1 - 7.7e-05 22.0 0.0 0.00021 20.6 0.0 1.7 1 0 0 1 1 1 1 tRNase Z endonuclease Pkinase PF00069.20 AIN95887.1 - 3.1e-61 206.8 0.0 4.5e-61 206.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AIN95887.1 - 8.7e-42 142.9 0.0 1.3e-41 142.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 AIN95887.1 - 1.6e-06 27.3 0.0 2.7e-06 26.5 0.0 1.3 1 0 0 1 1 1 1 Kinase-like DUF3049 PF11250.3 AIN95889.1 - 0.82 9.4 3.0 7.7 6.3 0.2 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3049) Dpy-30 PF05186.8 AIN95890.1 - 1.3e-07 31.0 0.7 3.7e-07 29.4 0.1 2.0 2 0 0 2 2 2 1 Dpy-30 motif DUF2453 PF10507.4 AIN95891.1 - 1.1e-36 124.9 1.6 4.2e-36 123.1 1.1 2.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2453) DnaJ PF00226.26 AIN95893.1 - 4e-21 74.5 1.5 8.2e-11 41.4 0.1 2.7 2 1 0 2 2 2 2 DnaJ domain DUF3854 PF12965.2 AIN95893.1 - 0.016 14.8 0.1 0.14 11.8 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3854) AAA_5 PF07728.9 AIN95894.1 - 8.8e-83 274.9 0.0 4e-32 110.8 0.0 3.7 3 0 0 3 3 3 3 AAA domain (dynein-related subfamily) VWA_2 PF13519.1 AIN95894.1 - 2.6e-09 37.4 0.0 7.8e-09 35.8 0.0 1.9 1 0 0 1 1 1 1 von Willebrand factor type A domain AAA_16 PF13191.1 AIN95894.1 - 6.2e-08 32.8 5.7 0.0013 18.7 0.0 5.1 6 0 0 6 6 5 2 AAA ATPase domain AAA PF00004.24 AIN95894.1 - 1.2e-05 25.4 0.1 0.075 13.2 0.0 3.2 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.1 AIN95894.1 - 6e-05 22.9 0.0 0.15 11.9 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.1 AIN95894.1 - 0.00016 21.8 0.2 0.053 13.6 0.0 3.5 2 2 0 2 2 2 1 AAA domain AAA_29 PF13555.1 AIN95894.1 - 0.00016 21.1 0.0 0.3 10.6 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain VWA PF00092.23 AIN95894.1 - 0.00039 20.1 0.0 0.001 18.8 0.0 1.7 1 0 0 1 1 1 1 von Willebrand factor type A domain AAA_3 PF07726.6 AIN95894.1 - 0.00055 19.5 0.0 0.23 11.0 0.0 2.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 AIN95894.1 - 0.00092 20.0 0.0 0.11 13.3 0.0 2.8 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.12 AIN95894.1 - 0.0014 18.0 0.0 0.16 11.3 0.0 3.1 3 0 0 3 3 3 1 IstB-like ATP binding protein AAA_33 PF13671.1 AIN95894.1 - 0.0035 17.2 0.0 0.25 11.2 0.0 3.3 2 0 0 2 2 2 1 AAA domain Sigma54_activat PF00158.21 AIN95894.1 - 0.0057 16.1 0.1 4.3 6.7 0.0 3.4 3 0 0 3 3 3 1 Sigma-54 interaction domain Mg_chelatase PF01078.16 AIN95894.1 - 0.0098 15.0 1.0 0.6 9.2 0.0 3.3 4 0 0 4 4 4 1 Magnesium chelatase, subunit ChlI AAA_2 PF07724.9 AIN95894.1 - 0.011 15.6 0.0 1.7 8.5 0.0 2.7 2 0 0 2 2 2 0 AAA domain (Cdc48 subfamily) UPF0079 PF02367.12 AIN95894.1 - 0.013 15.1 0.0 0.83 9.2 0.0 2.4 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 Zeta_toxin PF06414.7 AIN95894.1 - 0.013 14.6 0.0 2.7 7.0 0.0 3.3 3 0 0 3 3 3 0 Zeta toxin DUF815 PF05673.8 AIN95894.1 - 0.016 14.1 0.1 1.9 7.3 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) DUF258 PF03193.11 AIN95894.1 - 0.04 13.1 0.0 3.7 6.7 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function, DUF258 ABC_tran PF00005.22 AIN95894.1 - 0.052 13.8 0.0 1.2 9.4 0.0 2.9 2 0 0 2 2 2 0 ABC transporter SMC_N PF02463.14 AIN95894.1 - 0.083 12.1 0.0 1.6 7.9 0.0 2.2 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain ResIII PF04851.10 AIN95894.1 - 0.084 12.6 0.1 0.24 11.2 0.0 1.7 2 0 0 2 2 1 0 Type III restriction enzyme, res subunit Rad17 PF03215.10 AIN95894.1 - 0.12 11.0 0.0 0.22 10.1 0.0 1.3 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein RNA_helicase PF00910.17 AIN95894.1 - 0.13 12.4 0.0 1.1 9.4 0.0 2.3 2 0 0 2 2 2 0 RNA helicase AAA_18 PF13238.1 AIN95894.1 - 0.2 11.9 0.0 3.3 8.0 0.0 2.6 2 0 0 2 2 2 0 AAA domain Peptidase_C1 PF00112.18 AIN95895.1 - 6.6e-70 235.4 2.0 1.1e-69 234.7 1.4 1.3 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.7 AIN95895.1 - 7.1e-11 42.2 2.2 1.2e-10 41.4 1.5 1.4 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) DUF3586 PF12131.3 AIN95895.1 - 3.8e-10 39.6 0.2 7.6e-10 38.6 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3586) Peptidase_C1_2 PF03051.10 AIN95895.1 - 0.00013 20.6 0.3 0.0086 14.6 0.1 2.2 2 0 0 2 2 2 2 Peptidase C1-like family Hist_deacetyl PF00850.14 AIN95896.1 - 1.4e-58 198.6 0.0 2.1e-58 198.0 0.0 1.2 1 0 0 1 1 1 1 Histone deacetylase domain zf-RING_2 PF13639.1 AIN95897.1 - 1.1e-08 34.7 6.5 1.1e-08 34.7 4.5 3.9 4 0 0 4 4 4 2 Ring finger domain zf-C3HC4_2 PF13923.1 AIN95897.1 - 1.8e-05 24.6 7.4 1.8e-05 24.6 5.2 4.4 4 1 0 4 4 4 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 AIN95897.1 - 0.00025 20.6 7.2 0.00025 20.6 5.0 4.6 4 1 0 4 4 4 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 AIN95897.1 - 0.0044 16.6 6.4 0.0044 16.6 4.4 4.6 4 1 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 AIN95897.1 - 0.006 16.2 5.7 0.006 16.2 4.0 4.1 4 1 0 4 4 4 1 zinc-RING finger domain zf-HC5HC2H PF13771.1 AIN95897.1 - 0.026 14.6 2.3 0.026 14.6 1.6 4.3 2 1 3 5 5 5 0 PHD-like zinc-binding domain cwf21 PF08312.7 AIN95898.1 - 0.076 12.8 1.0 0.35 10.7 0.0 2.8 3 1 0 3 3 3 0 cwf21 domain DUF2666 PF10869.3 AIN95898.1 - 0.16 11.9 1.8 0.23 11.4 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2666) SnAC PF14619.1 AIN95898.1 - 0.32 11.2 5.6 0.16 12.1 0.4 2.9 3 0 0 3 3 3 0 Snf2-ATP coupling, chromatin remodelling complex TPR_11 PF13414.1 AIN95899.1 - 2e-66 219.5 26.9 5.8e-19 67.5 0.5 6.4 5 1 0 6 6 6 6 TPR repeat TPR_1 PF00515.23 AIN95899.1 - 2.2e-51 169.4 34.4 1e-07 31.2 0.0 9.5 9 0 0 9 9 9 9 Tetratricopeptide repeat TPR_2 PF07719.12 AIN95899.1 - 9.1e-42 137.6 36.4 2.6e-05 23.7 0.0 9.8 10 0 0 10 10 9 9 Tetratricopeptide repeat TPR_16 PF13432.1 AIN95899.1 - 5.5e-25 87.4 11.5 2.9e-05 24.6 0.1 6.5 6 0 0 6 6 6 6 Tetratricopeptide repeat TPR_12 PF13424.1 AIN95899.1 - 1.2e-20 73.2 22.7 1e-07 31.7 0.3 6.5 3 3 4 7 7 7 5 Tetratricopeptide repeat TPR_19 PF14559.1 AIN95899.1 - 4e-19 68.7 6.7 0.02 15.1 0.0 6.8 4 2 1 6 6 6 5 Tetratricopeptide repeat TPR_14 PF13428.1 AIN95899.1 - 4.9e-19 67.0 7.7 0.067 13.8 0.0 9.5 4 3 6 10 10 10 4 Tetratricopeptide repeat Apc3 PF12895.2 AIN95899.1 - 5.7e-15 55.2 21.2 5.6e-07 29.6 3.3 4.9 3 3 1 4 4 4 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.1 AIN95899.1 - 1.7e-14 52.7 12.7 0.32 11.3 0.1 8.4 8 0 0 8 8 8 5 Tetratricopeptide repeat TPR_8 PF13181.1 AIN95899.1 - 1.1e-12 46.7 27.8 0.051 13.3 0.0 9.0 8 1 1 9 9 9 4 Tetratricopeptide repeat TPR_7 PF13176.1 AIN95899.1 - 9.7e-11 40.6 13.7 0.18 11.7 0.0 8.7 8 1 0 8 8 8 2 Tetratricopeptide repeat TPR_9 PF13371.1 AIN95899.1 - 2e-10 40.3 4.4 0.00028 20.6 0.0 6.3 6 2 1 7 7 7 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 AIN95899.1 - 2.9e-07 30.2 2.5 1 9.2 0.0 5.9 7 0 0 7 7 7 2 Fis1 C-terminal tetratricopeptide repeat TPR_10 PF13374.1 AIN95899.1 - 0.00018 21.3 9.7 12 5.9 0.0 7.3 8 0 0 8 8 7 0 Tetratricopeptide repeat MIT PF04212.13 AIN95899.1 - 0.00063 19.5 21.7 0.79 9.6 0.1 7.2 7 1 0 7 7 7 2 MIT (microtubule interacting and transport) domain TPR_20 PF14561.1 AIN95899.1 - 0.0024 17.9 3.7 1.7 8.8 0.0 4.5 4 1 0 4 4 4 1 Tetratricopeptide repeat SHNi-TPR PF10516.4 AIN95899.1 - 0.0027 16.9 7.9 0.53 9.5 0.0 5.1 6 0 0 6 6 6 1 SHNi-TPR DUF3856 PF12968.2 AIN95899.1 - 0.052 13.3 9.2 5.8 6.7 0.1 5.0 3 3 2 5 5 5 0 Domain of Unknown Function (DUF3856) TPR_6 PF13174.1 AIN95899.1 - 0.16 12.4 28.4 4.6 7.9 0.1 8.4 9 0 0 9 9 7 0 Tetratricopeptide repeat Tom37_C PF11801.3 AIN95899.1 - 0.4 10.5 7.8 0.038 13.8 1.8 2.0 2 0 0 2 2 2 0 Tom37 C-terminal domain TPR_3 PF07720.7 AIN95899.1 - 0.42 10.4 25.2 0.14 11.9 0.7 6.2 6 0 0 6 6 6 0 Tetratricopeptide repeat DUF1126 PF06565.7 AIN95900.1 - 4.3e-14 51.6 0.1 2.1e-11 43.0 0.0 2.6 2 0 0 2 2 2 2 Repeat of unknown function (DUF1126) EF-hand_1 PF00036.27 AIN95900.1 - 0.0032 16.6 0.0 0.011 15.0 0.0 1.9 1 0 0 1 1 1 1 EF hand EF-hand_5 PF13202.1 AIN95900.1 - 0.046 13.0 0.0 0.13 11.6 0.0 1.8 1 0 0 1 1 1 0 EF hand EF-hand_7 PF13499.1 AIN95900.1 - 0.05 13.7 0.0 4.3 7.5 0.0 2.7 1 1 1 2 2 2 0 EF-hand domain pair EF-hand_6 PF13405.1 AIN95900.1 - 0.073 12.9 0.0 0.9 9.5 0.0 2.8 3 0 0 3 3 3 0 EF-hand domain EF-hand_8 PF13833.1 AIN95900.1 - 0.1 12.2 0.0 0.36 10.4 0.0 1.9 1 0 0 1 1 1 0 EF-hand domain pair Pribosyltran_N PF13793.1 AIN95901.1 - 1.1e-35 121.8 0.1 2.9e-35 120.5 0.0 1.7 1 0 0 1 1 1 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.1 AIN95901.1 - 2.7e-22 79.4 0.6 1.1e-21 77.4 0.2 1.9 1 1 1 2 2 2 1 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.22 AIN95901.1 - 5.2e-14 52.0 2.1 1.5e-13 50.5 1.5 1.8 1 1 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.1 AIN95901.1 - 0.0065 15.7 0.1 0.012 14.8 0.1 1.4 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase DUF4392 PF14336.1 AIN95901.1 - 0.057 12.2 0.0 0.088 11.5 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4392) Sec3_C PF09763.4 AIN95903.1 - 4.3e-77 259.8 0.0 1.2e-76 258.4 0.0 1.7 1 1 0 1 1 1 1 Exocyst complex component Sec3 DUF2450 PF10475.4 AIN95903.1 - 0.026 13.4 6.1 0.053 12.4 4.2 1.4 1 0 0 1 1 1 0 Protein of unknown function N-terminal domain (DUF2450) DUF972 PF06156.8 AIN95903.1 - 0.13 12.6 2.2 0.39 11.0 1.5 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF972) IncA PF04156.9 AIN95903.1 - 0.19 11.3 7.9 0.39 10.2 5.5 1.5 1 0 0 1 1 1 0 IncA protein TPMT PF05724.6 AIN95904.1 - 4.3e-17 62.2 0.0 8.9e-17 61.2 0.0 1.4 1 0 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) Methyltransf_23 PF13489.1 AIN95904.1 - 0.001 18.8 0.0 0.0016 18.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 AIN95904.1 - 0.11 13.1 0.0 0.17 12.4 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.1 AIN95904.1 - 0.19 11.3 0.0 0.28 10.7 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain FAST_1 PF06743.10 AIN95905.1 - 0.00074 19.1 0.4 0.38 10.5 0.0 3.9 3 1 1 4 4 4 1 FAST kinase-like protein, subdomain 1 plasmid_Toxin PF12703.2 AIN95905.1 - 1.5 8.6 5.0 0.58 10.0 0.1 2.8 4 0 0 4 4 4 0 Toxin of toxin-antitoxin type 1 system Slu7 PF11708.3 AIN95906.1 - 0.0012 18.6 6.1 0.0018 18.1 2.5 2.4 2 1 0 2 2 2 1 Pre-mRNA splicing Prp18-interacting factor zf-CCHC_5 PF14787.1 AIN95906.1 - 0.0021 17.4 0.9 0.0042 16.5 0.6 1.5 1 0 0 1 1 1 1 GAG-polyprotein viral zinc-finger BTK PF00779.14 AIN95906.1 - 0.0027 17.2 1.9 0.0056 16.2 1.3 1.5 1 0 0 1 1 1 1 BTK motif tRNA-synt_1c PF00749.16 AIN95906.1 - 0.051 12.2 0.2 0.088 11.4 0.1 1.3 1 0 0 1 1 1 0 tRNA synthetases class I (E and Q), catalytic domain Coatomer_WDAD PF04053.9 AIN95907.1 - 1.1e-11 44.1 2.6 0.00065 18.6 0.1 4.5 5 0 0 5 5 5 2 Coatomer WD associated region WD40 PF00400.27 AIN95907.1 - 6.9e-07 28.9 9.6 0.47 10.4 0.0 6.6 6 0 0 6 6 6 3 WD domain, G-beta repeat TPR_7 PF13176.1 AIN95907.1 - 6.7e-05 22.3 6.1 0.041 13.6 0.3 4.4 4 0 0 4 4 4 2 Tetratricopeptide repeat eIF2A PF08662.6 AIN95907.1 - 0.00099 18.8 0.1 0.041 13.5 0.0 2.7 2 1 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A Clathrin PF00637.15 AIN95907.1 - 0.0091 15.5 7.5 1.1 8.8 0.1 4.4 3 1 2 5 5 5 1 Region in Clathrin and VPS TPR_14 PF13428.1 AIN95907.1 - 0.025 15.1 11.1 0.13 12.9 0.5 4.7 4 0 0 4 4 4 0 Tetratricopeptide repeat zf-RanBP PF00641.13 AIN95907.1 - 0.028 13.5 12.3 0.032 13.3 2.9 2.7 2 0 0 2 2 2 0 Zn-finger in Ran binding protein and others Vps39_1 PF10366.4 AIN95907.1 - 0.039 13.9 0.3 0.15 12.0 0.2 2.0 1 0 0 1 1 1 0 Vacuolar sorting protein 39 domain 1 TPR_12 PF13424.1 AIN95907.1 - 0.14 12.1 15.2 0.31 11.0 0.1 4.3 4 1 0 4 4 4 0 Tetratricopeptide repeat TPR_8 PF13181.1 AIN95907.1 - 0.19 11.6 0.9 1.4 8.8 0.2 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_1 PF00515.23 AIN95907.1 - 1 9.1 7.1 1.6 8.4 0.4 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.12 AIN95907.1 - 3.2 7.8 19.0 0.68 9.9 0.8 5.0 5 0 0 5 5 5 0 Tetratricopeptide repeat DZR PF12773.2 AIN95907.1 - 7.6 6.4 13.6 62 3.5 9.4 2.5 1 1 0 1 1 1 0 Double zinc ribbon zf-C3HC4_2 PF13923.1 AIN95910.1 - 1.2e-10 41.1 8.8 2.5e-10 40.1 6.1 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 AIN95910.1 - 1.4e-09 37.4 7.6 2.8e-09 36.4 5.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 AIN95910.1 - 1.7e-08 34.1 5.9 4.4e-08 32.8 4.1 1.8 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.1 AIN95910.1 - 3.9e-08 32.9 8.7 7.8e-08 32.0 6.0 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 AIN95910.1 - 1.1e-07 31.4 6.5 2.4e-07 30.3 4.5 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 AIN95910.1 - 1.7e-06 27.5 7.0 3.4e-06 26.6 4.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 AIN95910.1 - 2.2e-05 24.0 2.1 2.2e-05 24.0 1.5 2.0 1 1 0 1 1 1 1 RING-type zinc-finger zf-rbx1 PF12678.2 AIN95910.1 - 0.0019 18.2 3.6 0.0058 16.7 2.5 1.8 1 1 0 1 1 1 1 RING-H2 zinc finger zf-Apc11 PF12861.2 AIN95910.1 - 0.1 12.4 2.4 0.22 11.3 1.6 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-Nse PF11789.3 AIN95910.1 - 1.1 8.8 6.6 2.3 7.8 4.6 1.6 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit GBA2_N PF12215.3 AIN95912.1 - 0.059 12.5 0.1 0.064 12.4 0.1 1.0 1 0 0 1 1 1 0 beta-Glucocerebrosidase 2 N terminal MGDG_synth PF06925.6 AIN95912.1 - 0.12 12.2 0.2 0.14 12.0 0.1 1.1 1 0 0 1 1 1 0 Monogalactosyldiacylglycerol (MGDG) synthase DUF4040 PF13244.1 AIN95913.1 - 1.8 8.5 6.7 2.9 7.9 0.7 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4040) Pkinase PF00069.20 AIN95916.1 - 6.1e-49 166.5 0.0 9.4e-49 165.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AIN95916.1 - 3.6e-34 118.0 0.0 5.9e-34 117.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 AIN95916.1 - 4.7e-06 25.7 0.0 8e-06 25.0 0.0 1.3 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.17 AIN95916.1 - 0.0097 15.2 0.0 0.022 14.1 0.0 1.5 1 0 0 1 1 1 1 RIO1 family SYCE1 PF15233.1 AIN95917.1 - 0.0073 16.2 5.7 0.012 15.5 3.9 1.4 1 1 0 1 1 1 1 Synaptonemal complex central element protein 1 PIN_2 PF10130.4 AIN95917.1 - 0.031 14.3 1.0 0.048 13.6 0.3 1.6 1 1 1 2 2 2 0 PIN domain DUF3138 PF11336.3 AIN95917.1 - 0.04 12.0 0.2 0.049 11.8 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) DUF1192 PF06698.6 AIN95917.1 - 0.047 13.5 0.6 0.047 13.5 0.4 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF1192) Pro_dh PF01619.13 AIN95917.1 - 0.075 12.0 1.2 0.091 11.7 0.9 1.0 1 0 0 1 1 1 0 Proline dehydrogenase DUF3573 PF12097.3 AIN95917.1 - 0.12 10.9 0.4 0.12 11.0 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) NuA4 PF09340.5 AIN95917.1 - 0.14 11.8 3.2 0.25 10.9 2.2 1.5 1 0 0 1 1 1 0 Histone acetyltransferase subunit NuA4 zf-ZPR1 PF03367.8 AIN95917.1 - 0.15 11.1 1.3 0.21 10.7 0.2 1.7 2 0 0 2 2 2 0 ZPR1 zinc-finger domain ATG16 PF08614.6 AIN95917.1 - 0.2 11.4 9.9 0.29 10.9 6.1 1.7 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) RNA_pol_Rpc82 PF05645.8 AIN95917.1 - 0.24 10.9 3.0 0.32 10.4 1.4 1.7 1 1 1 2 2 2 0 RNA polymerase III subunit RPC82 TPR_MLP1_2 PF07926.7 AIN95917.1 - 0.25 11.0 6.4 0.36 10.5 4.3 1.4 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein DivIC PF04977.10 AIN95917.1 - 0.45 10.0 5.3 5.1 6.6 1.2 2.3 2 0 0 2 2 2 0 Septum formation initiator DUF4200 PF13863.1 AIN95917.1 - 0.48 10.3 7.7 0.27 11.1 2.3 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) SlyX PF04102.7 AIN95917.1 - 0.64 10.4 4.5 2.7 8.4 0.4 2.3 2 0 0 2 2 2 0 SlyX DUF2415 PF10313.4 AIN95918.1 - 0.03 13.9 0.1 0.12 12.0 0.0 2.0 2 0 0 2 2 2 0 Uncharacterised protein domain (DUF2415) DUF3312 PF11768.3 AIN95918.1 - 0.048 11.8 0.0 0.68 8.0 0.0 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF3312) WD40 PF00400.27 AIN95918.1 - 0.35 10.8 10.7 3.4 7.7 0.0 5.3 5 1 0 5 5 5 0 WD domain, G-beta repeat PEX11 PF05648.9 AIN95921.1 - 2.5e-09 36.7 2.3 2.5e-06 26.9 1.6 2.5 1 1 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) PIG-L PF02585.12 AIN95922.1 - 1.5e-24 86.8 0.0 2.4e-24 86.2 0.0 1.2 1 0 0 1 1 1 1 GlcNAc-PI de-N-acetylase HhH-GPD PF00730.20 AIN95923.1 - 2.9e-19 69.3 0.0 4.7e-19 68.6 0.0 1.3 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.18 AIN95923.1 - 8.1e-08 31.5 0.0 2.1e-07 30.2 0.0 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix motif EndIII_4Fe-2S PF10576.4 AIN95923.1 - 0.00015 21.8 1.9 0.00026 21.0 1.3 1.4 1 0 0 1 1 1 1 Iron-sulfur binding domain of endonuclease III HHH_5 PF14520.1 AIN95923.1 - 0.0012 18.9 0.2 0.16 12.1 0.1 2.3 1 1 1 2 2 2 2 Helix-hairpin-helix domain RRM_1 PF00076.17 AIN95924.1 - 4.7e-19 67.7 0.0 5.9e-19 67.4 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 AIN95924.1 - 4.7e-15 55.3 0.0 6.6e-15 54.8 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 AIN95924.1 - 2.2e-08 33.8 0.0 3.2e-08 33.2 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RNA_bind PF08675.6 AIN95924.1 - 0.13 12.3 0.0 0.22 11.5 0.0 1.6 1 1 0 1 1 1 0 RNA binding domain Rogdi_lz PF10259.4 AIN95924.1 - 0.14 11.2 0.0 0.18 10.8 0.0 1.1 1 0 0 1 1 1 0 Rogdi leucine zipper containing protein HA2 PF04408.18 AIN95925.1 - 8.2e-18 64.3 0.8 4.2e-17 62.0 0.0 2.6 3 0 0 3 3 3 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 AIN95925.1 - 2e-12 46.9 0.0 4.6e-12 45.7 0.0 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.26 AIN95925.1 - 1.3e-10 40.9 0.0 3.7e-10 39.5 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 AIN95925.1 - 1.9e-10 40.5 0.1 5.4e-10 39.0 0.1 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase RWD PF05773.17 AIN95925.1 - 5.1e-07 29.5 0.0 1.6e-06 27.9 0.0 1.9 1 0 0 1 1 1 1 RWD domain T2SE PF00437.15 AIN95925.1 - 3.8e-05 22.7 0.0 8.1e-05 21.6 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_22 PF13401.1 AIN95925.1 - 0.00012 22.2 0.3 0.0021 18.2 0.0 2.9 2 0 0 2 2 2 1 AAA domain zf-CCHC PF00098.18 AIN95925.1 - 0.00013 21.6 1.0 0.00013 21.6 0.7 2.6 2 0 0 2 2 2 1 Zinc knuckle AAA_19 PF13245.1 AIN95925.1 - 0.02 14.6 0.0 0.076 12.7 0.0 2.0 1 0 0 1 1 1 0 Part of AAA domain Zeta_toxin PF06414.7 AIN95925.1 - 0.029 13.4 0.0 0.079 12.0 0.0 1.7 1 1 0 1 1 1 0 Zeta toxin AAA_25 PF13481.1 AIN95925.1 - 0.048 13.0 0.2 2.3 7.5 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_11 PF13086.1 AIN95925.1 - 0.05 13.1 0.1 0.19 11.2 0.0 1.9 1 1 0 1 1 1 0 AAA domain KaiC PF06745.8 AIN95925.1 - 0.051 12.6 0.0 0.12 11.4 0.0 1.6 1 0 0 1 1 1 0 KaiC AAA_23 PF13476.1 AIN95925.1 - 0.055 13.7 0.7 0.16 12.3 0.0 2.0 2 0 0 2 2 2 0 AAA domain Sigma54_activ_2 PF14532.1 AIN95925.1 - 0.066 13.2 0.0 0.49 10.4 0.0 2.4 2 0 0 2 2 2 0 Sigma-54 interaction domain RRM_1 PF00076.17 AIN95926.1 - 5.7e-18 64.3 0.0 1.1e-17 63.4 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 AIN95926.1 - 4.2e-13 49.0 0.0 6.9e-13 48.3 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 AIN95926.1 - 1.5e-08 34.3 0.0 2.5e-08 33.6 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 AIN95927.1 - 2e-16 59.3 0.0 3.2e-16 58.7 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 AIN95927.1 - 1.6e-09 37.6 0.0 2.5e-09 36.9 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 AIN95927.1 - 4e-06 26.5 0.0 6.9e-06 25.8 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Sporozoite_P67 PF05642.6 AIN95927.1 - 3.4 5.4 5.0 0.63 7.8 0.3 1.8 2 0 0 2 2 2 0 Sporozoite P67 surface antigen EF-hand_7 PF13499.1 AIN95928.1 - 1.1e-09 38.2 4.9 1.5e-09 37.8 1.8 2.5 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.27 AIN95928.1 - 2.9e-07 29.3 3.0 0.016 14.4 0.0 3.3 3 0 0 3 3 3 2 EF hand EF-hand_8 PF13833.1 AIN95928.1 - 1.3e-05 24.6 1.2 0.00087 18.8 0.4 2.6 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 AIN95928.1 - 0.00012 21.6 1.6 0.41 10.6 0.1 3.1 3 0 0 3 3 3 2 EF-hand domain Tropomyosin PF00261.15 AIN95928.1 - 0.018 14.1 61.5 0.92 8.5 26.6 3.3 1 1 1 2 2 2 0 Tropomyosin DUF3584 PF12128.3 AIN95928.1 - 0.85 6.8 61.8 0.061 10.6 22.9 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) MscS_porin PF12795.2 AIN95928.1 - 1 8.5 46.1 0.34 10.1 7.2 3.3 1 1 1 3 3 3 0 Mechanosensitive ion channel porin domain Reo_sigmaC PF04582.7 AIN95928.1 - 2.7 7.0 7.8 5.2 6.1 1.2 2.5 2 0 0 2 2 2 0 Reovirus sigma C capsid protein AAA_13 PF13166.1 AIN95928.1 - 9.8 4.4 30.7 15 3.8 11.3 2.2 1 1 1 2 2 2 0 AAA domain Kinesin PF00225.18 AIN95931.1 - 1.8e-75 253.7 8.5 1.6e-45 155.2 0.0 4.0 4 1 0 4 4 4 2 Kinesin motor domain AAA_22 PF13401.1 AIN95931.1 - 0.019 15.1 0.0 0.019 15.1 0.0 2.9 2 1 0 2 2 2 0 AAA domain DUF87 PF01935.12 AIN95931.1 - 1.1 9.0 0.0 1.1 9.0 0.0 3.4 3 1 0 3 3 3 0 Domain of unknown function DUF87 FHA PF00498.21 AIN95932.1 - 1.2e-14 54.1 0.0 4.2e-14 52.4 0.0 2.0 1 0 0 1 1 1 1 FHA domain zf-C3HC4 PF00097.20 AIN95932.1 - 1.9e-06 27.3 12.5 1.9e-06 27.3 8.7 3.4 4 1 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 AIN95932.1 - 9e-06 25.4 15.6 9e-06 25.4 10.8 3.8 3 2 0 4 4 4 1 Ring finger domain zf-RING_5 PF14634.1 AIN95932.1 - 3.1e-05 23.5 13.4 3.1e-05 23.5 9.3 3.9 3 1 1 4 4 4 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 AIN95932.1 - 3.7e-05 23.6 14.6 3.7e-05 23.6 10.1 3.6 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.1 AIN95932.1 - 5.6e-05 22.8 6.3 5.6e-05 22.8 4.3 3.2 3 1 1 4 4 4 1 zf-RING of BARD1-type protein zf-C3HC4_4 PF15227.1 AIN95932.1 - 0.00036 20.3 12.9 0.00036 20.3 9.0 3.4 4 1 1 5 5 5 1 zinc finger of C3HC4-type, RING PilZ PF07238.9 AIN95932.1 - 0.036 14.0 0.1 0.065 13.2 0.1 1.5 1 0 0 1 1 1 0 PilZ domain Vps39_2 PF10367.4 AIN95932.1 - 0.045 13.9 3.0 0.066 13.4 0.4 2.4 2 0 0 2 2 2 0 Vacuolar sorting protein 39 domain 2 zf-Nse PF11789.3 AIN95932.1 - 0.28 10.7 10.5 0.12 11.9 5.0 2.2 2 0 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit Atg8 PF02991.11 AIN95933.1 - 1.2e-06 28.3 0.0 1.9e-06 27.8 0.0 1.3 1 1 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like NRDE PF05742.7 AIN95935.1 - 3.8e-15 55.9 0.0 5.4e-13 48.8 0.0 3.1 3 0 0 3 3 3 2 NRDE protein DUF4586 PF15239.1 AIN95936.1 - 3e-35 122.2 4.3 5.4e-35 121.3 3.0 1.3 1 1 0 1 1 1 1 Domain of unknown function (DUF4586) VTC PF09359.5 AIN95937.1 - 7.2e-78 261.4 0.0 1.1e-77 260.8 0.0 1.3 1 0 0 1 1 1 1 VTC domain DUF3541 PF12060.3 AIN95937.1 - 0.018 14.3 0.7 0.064 12.5 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3541) Ferric_reduct PF01794.14 AIN95937.1 - 0.061 13.4 1.2 0.14 12.2 0.5 1.8 2 0 0 2 2 2 0 Ferric reductase like transmembrane component DUF202 PF02656.10 AIN95937.1 - 0.48 10.6 3.1 0.21 11.8 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF202) AAA_2 PF07724.9 AIN95938.1 - 3.8e-42 144.1 0.3 6.5e-34 117.3 0.1 2.4 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA PF00004.24 AIN95938.1 - 6.9e-13 48.9 0.4 4.8e-05 23.5 0.1 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 AIN95938.1 - 2.2e-06 27.4 0.1 7.4e-05 22.4 0.0 3.0 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) ClpB_D2-small PF10431.4 AIN95938.1 - 4.6e-06 26.4 0.2 2.3e-05 24.2 0.0 2.3 2 0 0 2 2 2 1 C-terminal, D2-small domain, of ClpB protein AAA_22 PF13401.1 AIN95938.1 - 7.6e-06 26.0 0.0 0.0026 17.9 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 AIN95938.1 - 7.5e-05 23.5 0.0 0.0019 19.0 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 AIN95938.1 - 0.00022 21.2 0.3 0.01 15.8 0.2 2.5 1 1 0 1 1 1 1 AAA ATPase domain AAA_18 PF13238.1 AIN95938.1 - 0.0012 19.0 0.0 0.042 14.1 0.0 2.5 2 0 0 2 2 2 1 AAA domain MCM PF00493.18 AIN95938.1 - 0.0017 17.2 0.2 0.039 12.7 0.0 2.3 2 0 0 2 2 2 1 MCM2/3/5 family ATP-synt_ab PF00006.20 AIN95938.1 - 0.0038 16.7 0.0 0.0079 15.7 0.0 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain Sigma54_activat PF00158.21 AIN95938.1 - 0.0096 15.4 0.5 0.15 11.5 0.0 2.8 3 1 0 3 3 3 1 Sigma-54 interaction domain Mg_chelatase PF01078.16 AIN95938.1 - 0.011 14.9 0.5 0.051 12.7 0.0 2.4 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI RuvB_N PF05496.7 AIN95938.1 - 0.012 14.6 0.2 0.29 10.1 0.0 2.7 2 1 1 3 3 3 0 Holliday junction DNA helicase ruvB N-terminus Zeta_toxin PF06414.7 AIN95938.1 - 0.023 13.7 0.1 0.13 11.3 0.0 2.2 1 1 1 2 2 2 0 Zeta toxin AAA_14 PF13173.1 AIN95938.1 - 0.035 14.0 0.1 9.8 6.0 0.0 2.8 2 1 0 2 2 2 0 AAA domain ResIII PF04851.10 AIN95938.1 - 0.043 13.6 0.0 0.8 9.5 0.0 2.5 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit IstB_IS21 PF01695.12 AIN95938.1 - 0.082 12.3 0.0 0.19 11.1 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein UCH PF00443.24 AIN95939.1 - 6.4e-40 136.9 0.0 2.7e-39 134.9 0.0 1.9 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 AIN95939.1 - 3.3e-07 30.0 0.0 2.7e-05 23.7 0.0 2.3 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase MCM PF00493.18 AIN95940.1 - 1.8e-119 398.4 0.0 7.9e-119 396.3 0.0 2.0 1 1 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 AIN95940.1 - 7.4e-11 42.5 0.0 3.6e-10 40.3 0.0 2.1 2 0 0 2 2 2 1 MCM N-terminal domain AAA_5 PF07728.9 AIN95940.1 - 3.7e-09 36.4 0.0 8.2e-09 35.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.16 AIN95940.1 - 5.9e-08 32.1 0.0 1.2e-05 24.6 0.0 2.6 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.21 AIN95940.1 - 0.0015 18.0 0.2 1.8 8.0 0.0 2.8 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_3 PF07726.6 AIN95940.1 - 0.0029 17.2 0.0 0.0074 15.9 0.0 1.7 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) G10 PF01125.12 AIN95941.1 - 3.1e-50 169.4 2.4 7e-46 155.3 1.2 2.1 2 0 0 2 2 2 2 G10 protein MFS_1 PF07690.11 AIN95942.1 - 2.1e-22 79.3 46.5 1e-15 57.3 16.9 2.2 1 1 0 2 2 2 2 Major Facilitator Superfamily Kinesin PF00225.18 AIN95944.1 - 8.1e-30 103.6 8.2 2.1e-10 39.8 0.0 4.0 3 1 1 4 4 4 3 Kinesin motor domain Wound_ind PF08186.6 AIN95944.1 - 0.03 14.2 0.2 0.071 13.0 0.1 1.6 1 0 0 1 1 1 0 Wound-inducible basic protein family Pkinase PF00069.20 AIN95946.1 - 7.6e-48 162.9 0.0 1.6e-47 161.8 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AIN95946.1 - 5.2e-19 68.3 0.0 3.7e-18 65.5 0.0 2.2 2 1 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 AIN95946.1 - 6.4e-06 25.3 0.0 1.1e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 AIN95946.1 - 0.0062 16.2 0.1 0.0062 16.2 0.1 2.4 2 2 0 2 2 2 1 Phosphotransferase enzyme family DUF1500 PF07389.7 AIN95949.1 - 0.058 13.4 0.9 0.17 11.9 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1500) EphA2_TM PF14575.1 AIN95949.1 - 0.1 12.9 0.9 7.2 7.0 0.0 2.5 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain zf-RING_2 PF13639.1 AIN95951.1 - 1.1e-08 34.8 7.3 1.1e-08 34.8 5.1 3.4 3 0 0 3 3 3 1 Ring finger domain zf-rbx1 PF12678.2 AIN95951.1 - 0.00012 22.0 10.4 0.00012 22.0 7.2 3.1 2 1 0 2 2 2 1 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 AIN95951.1 - 0.00013 21.8 8.2 0.00013 21.8 5.7 2.8 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 AIN95951.1 - 0.00032 20.3 5.8 0.00032 20.3 4.1 3.3 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 AIN95951.1 - 0.00034 20.2 2.2 0.00034 20.2 1.5 3.0 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 AIN95951.1 - 0.0004 20.1 1.3 0.0013 18.4 0.9 1.9 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_5 PF14634.1 AIN95951.1 - 0.0045 16.6 5.4 0.0045 16.6 3.8 2.9 3 0 0 3 3 3 1 zinc-RING finger domain FAD_binding_7 PF03441.9 AIN95952.1 - 5.8e-44 150.3 0.2 8.5e-44 149.8 0.2 1.2 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.13 AIN95952.1 - 4.2e-18 65.6 0.0 1.4e-17 63.9 0.0 1.9 1 0 0 1 1 1 1 DNA photolyase Ank_2 PF12796.2 AIN95953.1 - 1.7e-07 31.4 0.0 2.6e-07 30.9 0.0 1.3 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 AIN95953.1 - 1.3e-06 28.7 0.0 3.7e-06 27.3 0.0 1.8 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank PF00023.25 AIN95953.1 - 6e-05 22.6 0.3 0.0014 18.3 0.0 2.7 3 0 0 3 3 3 1 Ankyrin repeat Ank_5 PF13857.1 AIN95953.1 - 0.00025 21.1 0.0 0.00087 19.4 0.0 1.9 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 AIN95953.1 - 0.0011 18.9 0.1 0.0085 16.2 0.0 2.4 2 0 0 2 2 2 1 Ankyrin repeat WPP PF13943.1 AIN95953.1 - 0.16 12.2 1.5 0.26 11.5 1.1 1.4 1 0 0 1 1 1 0 WPP domain CHCH PF06747.8 AIN95954.1 - 0.0056 16.5 1.6 0.39 10.6 0.2 2.2 2 0 0 2 2 2 2 CHCH domain Cmc1 PF08583.5 AIN95954.1 - 0.036 13.8 2.0 0.35 10.6 1.3 2.0 1 1 0 1 1 1 0 Cytochrome c oxidase biogenesis protein Cmc1 like UPF0203 PF05254.7 AIN95954.1 - 0.069 13.0 1.3 1.5 8.7 0.7 2.1 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0203) Pet191_N PF10203.4 AIN95954.1 - 0.48 10.4 3.1 4.6 7.3 0.3 2.0 1 1 0 1 1 1 0 Cytochrome c oxidase assembly protein PET191 NDUF_B7 PF05676.8 AIN95954.1 - 2.1 7.8 4.5 7.4 6.0 0.4 2.1 1 1 1 2 2 2 0 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) DIE2_ALG10 PF04922.7 AIN95955.1 - 0.097 11.6 0.0 0.13 11.2 0.0 1.1 1 0 0 1 1 1 0 DIE2/ALG10 family AAA_13 PF13166.1 AIN95956.1 - 0.018 13.5 0.5 0.027 12.9 0.3 1.1 1 0 0 1 1 1 0 AAA domain DUF755 PF05501.6 AIN95956.1 - 0.14 12.2 7.9 0.28 11.2 3.5 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF755) Nterm_IS4 PF13006.2 AIN95956.1 - 0.46 10.5 7.8 0.086 12.8 1.0 2.7 3 0 0 3 3 3 0 Insertion element 4 transposase N-terminal DUF3259 PF11652.3 AIN95956.1 - 1.2 9.3 5.0 0.59 10.3 0.6 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF3259) DUF948 PF06103.6 AIN95956.1 - 3.9 7.3 6.9 1.9 8.3 0.1 3.1 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) Neur_chan_memb PF02932.11 AIN95956.1 - 6.8 6.4 9.9 8.6e+02 -0.4 6.9 2.9 1 1 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region API5 PF05918.6 AIN95957.1 - 1.2 7.5 0.8 2.6 6.4 0.5 1.5 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) Pkinase PF00069.20 AIN95958.1 - 2.2e-49 167.9 0.0 2.8e-49 167.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AIN95958.1 - 4.7e-16 58.6 0.0 7.4e-16 57.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 AIN95958.1 - 0.016 14.9 1.3 1.5 8.5 0.0 2.5 2 1 0 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.9 AIN95958.1 - 0.067 12.2 0.0 0.11 11.5 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pox_ser-thr_kin PF05445.6 AIN95958.1 - 0.19 10.4 0.0 0.27 9.9 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase DSPn PF14671.1 AIN95959.1 - 7.6e-21 74.5 0.0 2.3e-14 53.5 0.0 2.3 2 0 0 2 2 2 2 Dual specificity protein phosphatase, N-terminal half DSPc PF00782.15 AIN95959.1 - 1.5e-08 34.2 0.1 2.8e-08 33.4 0.1 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 AIN95959.1 - 0.00021 20.7 0.0 0.00042 19.7 0.0 1.4 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.1 AIN95959.1 - 0.096 12.9 0.4 0.31 11.2 0.3 1.8 2 0 0 2 2 2 0 Tyrosine phosphatase family HTH_28 PF13518.1 AIN95959.1 - 0.1 12.6 1.0 0.69 9.9 0.1 2.5 2 0 0 2 2 2 0 Helix-turn-helix domain PTPlike_phytase PF14566.1 AIN95959.1 - 0.4 10.7 0.7 0.78 9.7 0.5 1.4 1 0 0 1 1 1 0 Inositol hexakisphosphate zf-C3HC4_3 PF13920.1 AIN95960.1 - 9.8e-11 41.1 15.0 1.6e-10 40.5 10.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Plus-3 PF03126.13 AIN95960.1 - 1.1e-07 31.9 0.0 2.7e-07 30.5 0.0 1.8 1 0 0 1 1 1 1 Plus-3 domain zf-C3HC4_2 PF13923.1 AIN95960.1 - 0.76 9.8 17.7 1.4 8.9 12.3 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) TPR_11 PF13414.1 AIN95961.1 - 4e-23 80.8 11.1 4.7e-05 22.9 0.0 7.1 4 1 3 8 8 8 7 TPR repeat TPR_1 PF00515.23 AIN95961.1 - 2.4e-17 61.7 13.5 0.0025 17.3 0.0 9.1 9 0 0 9 9 9 4 Tetratricopeptide repeat TPR_2 PF07719.12 AIN95961.1 - 1.6e-12 46.3 23.4 0.07 13.0 0.0 8.7 10 0 0 10 10 10 5 Tetratricopeptide repeat TPR_14 PF13428.1 AIN95961.1 - 5.7e-11 42.0 20.1 0.19 12.4 0.0 8.1 4 2 5 9 9 8 4 Tetratricopeptide repeat TPR_12 PF13424.1 AIN95961.1 - 7.7e-09 35.3 18.6 0.055 13.4 0.0 6.6 3 2 3 6 6 6 4 Tetratricopeptide repeat TPR_8 PF13181.1 AIN95961.1 - 1e-08 34.3 0.4 0.84 9.5 0.0 6.7 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_16 PF13432.1 AIN95961.1 - 1.3e-08 35.2 17.1 0.049 14.3 0.6 6.8 5 2 4 9 9 9 5 Tetratricopeptide repeat TPR_9 PF13371.1 AIN95961.1 - 5.2e-08 32.6 10.5 0.00011 21.9 0.3 3.9 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_19 PF14559.1 AIN95961.1 - 1.3e-06 28.6 11.8 0.12 12.7 0.1 5.7 3 2 5 8 8 8 3 Tetratricopeptide repeat TPR_17 PF13431.1 AIN95961.1 - 0.00019 21.3 8.0 15 6.0 0.0 7.5 8 0 0 8 8 8 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 AIN95961.1 - 0.025 14.4 11.5 0.075 12.9 0.0 4.6 6 0 0 6 6 6 0 Fis1 C-terminal tetratricopeptide repeat TPR_6 PF13174.1 AIN95961.1 - 0.038 14.4 11.7 10 6.8 0.0 5.3 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_7 PF13176.1 AIN95961.1 - 0.061 13.1 5.0 80 3.4 0.0 5.6 6 0 0 6 6 6 0 Tetratricopeptide repeat Metallophos PF00149.23 AIN95964.1 - 9.8e-24 83.8 1.6 1.4e-23 83.3 1.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase IRK PF01007.15 AIN95965.1 - 7.1e-05 21.7 8.0 0.0028 16.5 0.2 3.1 3 0 0 3 3 3 3 Inward rectifier potassium channel Macoilin PF09726.4 AIN95965.1 - 0.54 8.4 13.9 0.72 8.0 9.6 1.1 1 0 0 1 1 1 0 Transmembrane protein Acyltransferase PF01553.16 AIN95966.1 - 0.0016 17.9 0.0 0.0036 16.7 0.0 1.6 1 0 0 1 1 1 1 Acyltransferase LRR_8 PF13855.1 AIN95970.1 - 0.012 15.3 8.9 4.5 7.0 0.1 4.6 3 2 1 4 4 4 0 Leucine rich repeat LRR_1 PF00560.28 AIN95970.1 - 0.015 15.2 1.5 1.7 8.9 0.0 4.4 4 0 0 4 4 4 0 Leucine Rich Repeat LRR_4 PF12799.2 AIN95970.1 - 0.21 11.2 6.5 2.4 7.8 0.0 4.2 4 2 0 4 4 4 0 Leucine Rich repeats (2 copies) LRR_6 PF13516.1 AIN95970.1 - 0.34 11.1 8.5 3.3 8.0 0.1 4.7 5 0 0 5 5 5 0 Leucine Rich repeat Nsp1_C PF05064.8 AIN95970.1 - 0.67 9.6 3.5 1.2 8.7 2.4 1.4 1 0 0 1 1 1 0 Nsp1-like C-terminal region ADIP PF11559.3 AIN95970.1 - 1.1 9.2 6.6 1.9 8.3 4.6 1.3 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding DSPc PF00782.15 AIN95972.1 - 6.9e-08 32.1 0.0 1.3e-06 28.0 0.0 2.4 1 1 0 1 1 1 1 Dual specificity phosphatase, catalytic domain 2-oxoacid_dh PF00198.18 AIN95972.1 - 0.065 12.4 0.0 0.11 11.7 0.0 1.3 1 0 0 1 1 1 0 2-oxoacid dehydrogenases acyltransferase (catalytic domain) His_Phos_1 PF00300.17 AIN95973.1 - 8.6e-12 45.4 0.0 2.2e-11 44.1 0.0 1.7 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) PDEase_II PF02112.10 AIN95973.1 - 0.033 13.1 0.0 0.048 12.5 0.0 1.2 1 0 0 1 1 1 0 cAMP phosphodiesterases class-II His_Phos_2 PF00328.17 AIN95973.1 - 0.052 12.8 0.0 0.73 9.1 0.0 2.0 2 0 0 2 2 2 0 Histidine phosphatase superfamily (branch 2) FUSC PF04632.7 AIN95974.1 - 0.65 8.3 5.7 4.7 5.5 0.7 2.2 2 0 0 2 2 2 0 Fusaric acid resistance protein family LRR_8 PF13855.1 AIN95975.1 - 7e-05 22.5 0.0 0.0058 16.3 0.0 2.4 2 0 0 2 2 2 2 Leucine rich repeat LRR_4 PF12799.2 AIN95975.1 - 0.021 14.4 0.1 7.1 6.3 0.0 2.9 1 1 2 3 3 3 0 Leucine Rich repeats (2 copies) UvrD-helicase PF00580.16 AIN95976.1 - 4.3e-40 137.9 0.0 6.8e-20 71.6 0.0 2.3 1 1 1 2 2 2 2 UvrD/REP helicase N-terminal domain UvrD_C PF13361.1 AIN95976.1 - 6.1e-26 91.7 0.0 2.8e-12 46.7 0.0 2.5 2 0 0 2 2 2 2 UvrD-like helicase C-terminal domain AAA_19 PF13245.1 AIN95976.1 - 1.8e-12 46.8 1.9 6.5e-12 45.0 1.3 2.0 1 0 0 1 1 1 1 Part of AAA domain UvrD_C_2 PF13538.1 AIN95976.1 - 5.6e-09 36.0 0.0 2.7e-08 33.8 0.0 2.2 2 0 0 2 2 2 1 UvrD-like helicase C-terminal domain AAA_30 PF13604.1 AIN95976.1 - 1.1e-08 34.9 1.2 4.7e-06 26.3 0.2 2.6 2 0 0 2 2 2 2 AAA domain Peptidase_S51 PF03575.12 AIN95977.1 - 4.4e-19 68.7 0.0 3.7e-17 62.4 0.0 2.1 1 1 0 1 1 1 1 Peptidase family S51 PRKCSH-like PF12999.2 AIN95978.1 - 2.4e-08 33.7 0.9 4.7e-07 29.5 0.0 2.3 2 0 0 2 2 2 1 Glucosidase II beta subunit-like Ldl_recept_a PF00057.13 AIN95978.1 - 0.31 10.9 3.2 9.1 6.2 0.7 2.7 2 0 0 2 2 2 0 Low-density lipoprotein receptor domain class A DUF530 PF04409.7 AIN95979.1 - 0.13 10.3 0.0 0.2 9.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF530) SPX PF03105.14 AIN95979.1 - 0.26 11.0 4.1 1.5 8.5 1.4 2.3 2 0 0 2 2 2 0 SPX domain PH PF00169.24 AIN95980.1 - 1.3e-11 44.6 0.0 2.6e-11 43.6 0.0 1.5 1 0 0 1 1 1 1 PH domain Mcp5_PH PF12814.2 AIN95980.1 - 0.068 13.0 0.0 0.21 11.5 0.0 1.8 1 0 0 1 1 1 0 Meiotic cell cortex C-terminal pleckstrin homology zf-DHHC PF01529.15 AIN95981.1 - 4.1e-30 104.4 4.2 4.1e-30 104.4 2.9 2.3 2 2 0 2 2 2 1 DHHC palmitoyltransferase AAA_17 PF13207.1 AIN95982.1 - 1.2e-08 35.8 0.0 4.2e-08 34.0 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 AIN95982.1 - 4.3e-07 29.9 1.5 7.1e-07 29.2 0.1 2.1 1 1 1 2 2 2 1 AAA domain Zeta_toxin PF06414.7 AIN95982.1 - 5.1e-06 25.7 0.0 9.6e-06 24.8 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin AAA_18 PF13238.1 AIN95982.1 - 8.4e-06 26.1 0.1 3e-05 24.3 0.1 1.9 1 1 0 1 1 1 1 AAA domain APS_kinase PF01583.15 AIN95982.1 - 0.00019 21.0 0.1 0.0006 19.5 0.0 1.8 1 1 1 2 2 2 1 Adenylylsulphate kinase AAA_16 PF13191.1 AIN95982.1 - 0.00038 20.5 1.4 0.00096 19.1 0.2 2.2 2 1 0 2 2 2 1 AAA ATPase domain AAA_28 PF13521.1 AIN95982.1 - 0.0025 17.8 0.0 0.0073 16.2 0.0 1.8 2 0 0 2 2 2 1 AAA domain DUF258 PF03193.11 AIN95982.1 - 0.0037 16.4 0.0 0.0075 15.4 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_10 PF12846.2 AIN95982.1 - 0.005 16.3 0.0 0.014 14.8 0.0 1.7 2 0 0 2 2 2 1 AAA-like domain ABC_tran PF00005.22 AIN95982.1 - 0.015 15.6 0.0 0.03 14.5 0.0 1.5 1 0 0 1 1 1 0 ABC transporter PRK PF00485.13 AIN95982.1 - 0.047 13.2 0.0 0.084 12.4 0.0 1.4 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family AAA_29 PF13555.1 AIN95982.1 - 0.058 12.9 0.1 0.51 9.9 0.0 2.4 3 0 0 3 3 3 0 P-loop containing region of AAA domain CPT PF07931.7 AIN95982.1 - 0.073 12.6 0.0 0.16 11.5 0.0 1.6 1 1 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein AAA_22 PF13401.1 AIN95982.1 - 0.073 13.2 0.0 0.38 10.8 0.0 2.2 2 0 0 2 2 2 0 AAA domain CbiA PF01656.18 AIN95982.1 - 0.078 12.3 0.0 0.46 9.8 0.0 2.1 2 0 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain Sigma54_activat PF00158.21 AIN95982.1 - 0.12 11.8 0.0 5.5 6.4 0.0 2.4 2 0 0 2 2 2 0 Sigma-54 interaction domain RNA_helicase PF00910.17 AIN95982.1 - 0.15 12.2 0.0 0.41 10.8 0.0 1.7 1 0 0 1 1 1 0 RNA helicase DUF2075 PF09848.4 AIN95982.1 - 0.2 10.6 0.0 0.29 10.0 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) TYW3 PF02676.9 AIN95983.1 - 3.7e-40 137.2 0.0 9.4e-39 132.6 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase TYW3 Prefoldin_2 PF01920.15 AIN95984.1 - 1.4e-18 66.5 2.0 1.8e-18 66.2 1.4 1.1 1 0 0 1 1 1 1 Prefoldin subunit DASH_Dad3 PF08656.5 AIN95984.1 - 0.0024 17.5 3.0 0.0064 16.1 0.6 2.0 2 0 0 2 2 2 1 DASH complex subunit Dad3 DUF939_C PF11728.3 AIN95984.1 - 0.024 14.4 1.0 0.11 12.2 0.1 1.9 2 0 0 2 2 2 0 DUF939 C-terminal domain Spc24 PF08286.6 AIN95984.1 - 0.04 13.5 2.9 2.8 7.6 0.2 2.1 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 NTR2 PF15458.1 AIN95984.1 - 0.048 12.9 2.9 2.4 7.3 0.0 2.1 2 0 0 2 2 2 0 Nineteen complex-related protein 2 FliD_C PF07195.7 AIN95984.1 - 0.049 12.9 0.9 0.25 10.6 0.0 2.0 2 0 0 2 2 2 0 Flagellar hook-associated protein 2 C-terminus DUF4037 PF13228.1 AIN95984.1 - 0.06 13.5 0.2 2.1 8.6 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4037) TBPIP PF07106.8 AIN95984.1 - 0.067 12.7 2.2 1.1 8.8 0.3 2.1 2 0 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) APG6 PF04111.7 AIN95984.1 - 0.069 12.1 2.7 0.67 8.9 0.4 2.0 2 0 0 2 2 2 0 Autophagy protein Apg6 Prefoldin PF02996.12 AIN95984.1 - 0.12 12.0 2.4 0.79 9.3 1.7 2.0 1 1 0 1 1 1 0 Prefoldin subunit Microtub_bind PF13931.1 AIN95984.1 - 0.12 12.4 1.6 0.43 10.7 0.4 1.9 2 0 0 2 2 2 0 Kinesin-associated microtubule-binding Hemerythrin PF01814.18 AIN95984.1 - 0.18 11.9 2.4 1.4 9.0 1.9 1.9 1 1 1 2 2 2 0 Hemerythrin HHE cation binding domain DivIVA PF05103.8 AIN95984.1 - 0.36 10.8 3.8 2.6 8.0 0.4 2.1 2 0 0 2 2 2 0 DivIVA protein IncA PF04156.9 AIN95984.1 - 0.38 10.3 2.8 0.66 9.5 1.9 1.4 1 1 0 1 1 1 0 IncA protein SlyX PF04102.7 AIN95984.1 - 0.42 11.0 5.2 0.53 10.6 0.1 2.4 2 1 0 2 2 2 0 SlyX DUF342 PF03961.8 AIN95984.1 - 2.4 6.4 5.1 3.1 6.1 0.7 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF342) WXG100 PF06013.7 AIN95984.1 - 3.7 7.6 6.0 15 5.6 0.6 2.4 2 1 0 2 2 2 0 Proteins of 100 residues with WXG RNA12 PF10443.4 AIN95987.1 - 0.091 11.2 0.1 0.2 10.1 0.0 1.5 2 0 0 2 2 2 0 RNA12 protein zf-CCCH PF00642.19 AIN95988.1 - 2.6e-16 58.8 31.1 0.00025 20.6 0.2 5.5 5 0 0 5 5 5 5 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCHC PF00098.18 AIN95988.1 - 6.6e-07 28.9 6.1 0.00014 21.6 0.4 3.4 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_2 PF13696.1 AIN95988.1 - 3e-05 23.4 11.0 0.00033 20.0 0.6 3.1 2 0 0 2 2 2 2 Zinc knuckle zf-CCCH_2 PF14608.1 AIN95988.1 - 0.033 14.1 0.1 0.033 14.1 0.1 6.1 6 0 0 6 6 6 0 Zinc finger C-x8-C-x5-C-x3-H type zf-UBR PF02207.15 AIN95990.1 - 3.4e-16 58.7 14.9 3.4e-16 58.7 10.3 2.7 2 0 0 2 2 2 1 Putative zinc finger in N-recognin (UBR box) RdRP_4 PF02123.11 AIN95990.1 - 0.037 12.7 0.7 0.32 9.6 0.0 2.1 2 0 0 2 2 2 0 Viral RNA-directed RNA-polymerase ACBP PF00887.14 AIN95991.1 - 5.1e-24 83.7 1.0 9.7e-24 82.8 0.7 1.5 1 0 0 1 1 1 1 Acyl CoA binding protein Mad3_BUB1_II PF08171.6 AIN95991.1 - 0.16 11.8 0.1 0.54 10.1 0.1 1.8 2 0 0 2 2 2 0 Mad3/BUB1 homology region 2 DUF4486 PF14858.1 AIN95992.1 - 0.039 12.2 0.1 0.073 11.3 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4486) Luteo_P1-P2 PF08467.5 AIN95992.1 - 5.5 5.6 2.1 4.8 5.8 0.1 1.8 2 0 0 2 2 2 0 Luteovirus RNA polymerase P1-P2/replicase Peptidase_S9_N PF02897.10 AIN95993.1 - 6.6e-115 383.9 0.1 8.3e-115 383.6 0.0 1.1 1 0 0 1 1 1 1 Prolyl oligopeptidase, N-terminal beta-propeller domain Peptidase_S9 PF00326.16 AIN95993.1 - 1.4e-65 220.4 0.0 2.1e-65 219.9 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Esterase PF00756.15 AIN95993.1 - 0.037 13.4 0.0 0.23 10.8 0.0 2.0 1 1 0 1 1 1 0 Putative esterase DUF4464 PF14713.1 AIN95994.1 - 1.4e-83 279.8 0.1 1.7e-83 279.5 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4464) CENP-Q PF13094.1 AIN95995.1 - 0.013 15.4 1.4 0.033 14.2 1.0 1.6 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit HAP1_N PF04849.8 AIN95995.1 - 0.1 11.5 0.0 0.16 10.9 0.0 1.2 1 0 0 1 1 1 0 HAP1 N-terminal conserved region Prefoldin PF02996.12 AIN95997.1 - 6.5e-11 41.9 0.0 3.9e-10 39.4 0.0 2.0 2 0 0 2 2 2 1 Prefoldin subunit AAA PF00004.24 AIN95998.1 - 0.0018 18.4 0.0 0.0047 17.1 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Zeta_toxin PF06414.7 AIN95998.1 - 0.018 14.1 0.0 0.073 12.1 0.0 1.9 2 0 0 2 2 2 0 Zeta toxin AAA_16 PF13191.1 AIN95998.1 - 0.031 14.2 3.8 0.41 10.6 0.1 4.0 2 1 1 3 3 3 0 AAA ATPase domain AAA_17 PF13207.1 AIN95998.1 - 0.052 14.3 0.0 0.13 13.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain Torsin PF06309.6 AIN95998.1 - 0.11 12.3 0.0 2.6 7.9 0.0 2.3 2 0 0 2 2 2 0 Torsin DEAD PF00270.24 AIN95999.1 - 2.4e-25 89.0 0.1 4.1e-25 88.2 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 AIN95999.1 - 3.6e-18 65.2 0.0 1e-17 63.7 0.0 1.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 AIN95999.1 - 3.3e-05 23.7 0.0 6.2e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_19 PF13245.1 AIN95999.1 - 0.03 14.0 0.1 0.094 12.4 0.0 1.8 1 0 0 1 1 1 0 Part of AAA domain UPF0160 PF03690.8 AIN96000.1 - 3.2e-123 411.1 0.0 3.8e-123 410.9 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0160) Ras PF00071.17 AIN96001.1 - 3.1e-37 127.4 0.1 1.1e-11 44.4 0.0 3.1 3 0 0 3 3 3 3 Ras family Miro PF08477.8 AIN96001.1 - 2.1e-10 41.1 0.1 4.6e-09 36.8 0.0 2.6 2 1 0 2 2 2 1 Miro-like protein Arf PF00025.16 AIN96001.1 - 4.3e-05 22.8 0.0 0.33 10.1 0.0 2.9 3 0 0 3 3 3 2 ADP-ribosylation factor family AAA_22 PF13401.1 AIN96001.1 - 0.085 13.0 0.0 0.14 12.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain Phage_B PF02304.10 AIN96002.1 - 0.041 14.1 0.2 0.073 13.3 0.1 1.3 1 0 0 1 1 1 0 Scaffold protein B PEHE PF15275.1 AIN96002.1 - 1.1 9.7 3.6 1.4 9.3 2.3 1.4 1 1 0 1 1 1 0 PEHE domain DUF2011 PF09428.5 AIN96003.1 - 0.06 13.2 8.5 0.036 13.9 4.6 1.6 2 0 0 2 2 2 0 Fungal protein of unknown function (DUF2011) Bravo_FIGEY PF13882.1 AIN96003.1 - 0.1 13.5 4.6 0.34 11.8 3.2 1.8 1 0 0 1 1 1 0 Bravo-like intracellular region Hydrolase PF00702.21 AIN96005.1 - 4.1e-12 46.9 0.1 0.00016 22.1 0.0 3.8 3 0 0 3 3 3 3 haloacid dehalogenase-like hydrolase HAD PF12710.2 AIN96005.1 - 2e-09 37.9 0.0 1e-06 29.0 0.0 3.3 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.15 AIN96005.1 - 8.1e-08 31.5 0.0 8.3e-05 21.7 0.0 3.1 3 0 0 3 3 3 2 E1-E2 ATPase Hydrolase_3 PF08282.7 AIN96005.1 - 0.014 14.9 0.1 0.025 14.1 0.1 1.3 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 AIN96005.1 - 0.14 12.1 0.0 2.7 7.9 0.0 2.8 3 0 0 3 3 3 0 Putative hydrolase of sodium-potassium ATPase alpha subunit EF-hand_7 PF13499.1 AIN96006.1 - 8.2e-08 32.2 1.4 7.3e-07 29.2 0.1 2.3 1 1 1 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.1 AIN96006.1 - 4.2e-06 26.1 1.1 1.7e-05 24.3 0.0 2.6 4 0 0 4 4 4 1 EF-hand domain EF-hand_1 PF00036.27 AIN96006.1 - 1.5e-05 23.9 5.1 3.8e-05 22.6 0.0 3.1 3 0 0 3 3 3 1 EF hand EF-hand_8 PF13833.1 AIN96006.1 - 5.2e-05 22.7 1.7 0.014 15.0 0.5 2.6 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.1 AIN96006.1 - 0.037 13.3 0.0 0.037 13.3 0.0 3.4 4 0 0 4 4 4 0 EF hand EFhand_Ca_insen PF08726.5 AIN96006.1 - 0.043 13.7 0.7 0.89 9.5 0.2 2.4 2 1 0 2 2 2 0 Ca2+ insensitive EF hand DUF1456 PF07308.8 AIN96006.1 - 0.072 13.1 0.6 1.2 9.2 0.0 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF1456) YokU PF14122.1 AIN96006.1 - 0.2 11.3 3.9 1.1 8.9 0.5 2.7 1 1 1 2 2 2 0 YokU-like protein DUF1059 PF06348.6 AIN96006.1 - 0.21 11.4 1.6 0.28 11.0 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1059) EF-hand_1 PF00036.27 AIN96007.1 - 5.9e-43 140.9 12.3 2e-10 39.2 0.7 4.1 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 AIN96007.1 - 2.5e-38 130.0 4.2 2.2e-21 75.7 0.5 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.1 AIN96007.1 - 2.2e-33 113.6 11.2 2.3e-16 59.1 0.5 4.1 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_6 PF13405.1 AIN96007.1 - 2e-31 105.0 6.7 1.2e-09 37.2 0.1 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.1 AIN96007.1 - 2.9e-29 99.0 8.0 1.7e-07 30.2 0.0 4.2 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.1 AIN96007.1 - 8.6e-15 54.4 0.1 7.5e-08 32.1 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.2 AIN96007.1 - 1.1e-09 37.9 0.9 4.5e-05 23.1 0.1 2.3 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.4 AIN96007.1 - 3e-08 33.6 0.0 0.00049 20.0 0.0 2.1 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region UPF0154 PF03672.8 AIN96007.1 - 1.9e-06 27.3 1.8 0.18 11.4 0.0 3.9 4 1 1 5 5 5 2 Uncharacterised protein family (UPF0154) EFhand_Ca_insen PF08726.5 AIN96007.1 - 4.8e-06 26.4 1.2 5.9e-05 22.9 0.2 2.3 2 0 0 2 2 2 1 Ca2+ insensitive EF hand TerB PF05099.8 AIN96007.1 - 0.00022 20.9 0.3 0.082 12.6 0.0 2.2 1 1 1 2 2 2 2 Tellurite resistance protein TerB Caleosin PF05042.8 AIN96007.1 - 0.00025 20.6 0.1 0.013 15.0 0.1 2.5 1 1 0 1 1 1 1 Caleosin related protein EF-hand_like PF09279.6 AIN96007.1 - 0.00033 20.6 1.2 0.0031 17.5 0.1 2.4 2 1 0 2 2 2 1 Phosphoinositide-specific phospholipase C, efhand-like RNA_pol_Rpb4 PF03874.11 AIN96007.1 - 0.0038 17.2 0.5 1.7 8.6 0.1 2.4 2 0 0 2 2 2 1 RNA polymerase Rpb4 DUF1103 PF06513.6 AIN96007.1 - 0.0051 16.2 1.1 0.0059 16.0 0.8 1.1 1 0 0 1 1 1 1 Repeat of unknown function (DUF1103) MotA_activ PF09114.5 AIN96007.1 - 0.021 14.5 0.1 4.2 7.1 0.0 2.3 2 0 0 2 2 2 0 Transcription factor MotA, activation domain Poly_export PF02563.11 AIN96007.1 - 0.042 13.6 0.2 11 5.8 0.0 3.1 1 1 2 3 3 3 0 Polysaccharide biosynthesis/export protein LNS2 PF08235.8 AIN96007.1 - 0.045 13.3 0.1 0.33 10.4 0.0 1.9 2 0 0 2 2 2 0 LNS2 (Lipin/Ned1/Smp2) Tenui_NCP PF04876.7 AIN96007.1 - 0.064 12.8 0.1 0.95 8.9 0.0 2.1 1 1 1 2 2 2 0 Tenuivirus major non-capsid protein Toprim_2 PF13155.1 AIN96007.1 - 0.065 13.5 0.8 14 6.0 0.3 2.6 1 1 2 3 3 3 0 Toprim-like SpoVIF PF14069.1 AIN96007.1 - 0.077 12.7 0.8 1.6 8.5 0.1 2.6 3 0 0 3 3 3 0 Stage VI sporulation protein F DUF1880 PF08976.6 AIN96007.1 - 0.13 12.3 0.0 0.84 9.7 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF1880) EF-hand_1 PF00036.27 AIN96008.1 - 5.9e-43 140.9 12.3 2e-10 39.2 0.7 4.1 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 AIN96008.1 - 2.5e-38 130.0 4.2 2.2e-21 75.7 0.5 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.1 AIN96008.1 - 2.2e-33 113.6 11.2 2.3e-16 59.1 0.5 4.1 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_6 PF13405.1 AIN96008.1 - 2e-31 105.0 6.7 1.2e-09 37.2 0.1 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.1 AIN96008.1 - 2.9e-29 99.0 8.0 1.7e-07 30.2 0.0 4.2 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.1 AIN96008.1 - 8.6e-15 54.4 0.1 7.5e-08 32.1 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.2 AIN96008.1 - 1.1e-09 37.9 0.9 4.5e-05 23.1 0.1 2.3 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.4 AIN96008.1 - 3e-08 33.6 0.0 0.00049 20.0 0.0 2.1 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region UPF0154 PF03672.8 AIN96008.1 - 1.9e-06 27.3 1.8 0.18 11.4 0.0 3.9 4 1 1 5 5 5 2 Uncharacterised protein family (UPF0154) EFhand_Ca_insen PF08726.5 AIN96008.1 - 4.8e-06 26.4 1.2 5.9e-05 22.9 0.2 2.3 2 0 0 2 2 2 1 Ca2+ insensitive EF hand TerB PF05099.8 AIN96008.1 - 0.00022 20.9 0.3 0.082 12.6 0.0 2.2 1 1 1 2 2 2 2 Tellurite resistance protein TerB Caleosin PF05042.8 AIN96008.1 - 0.00025 20.6 0.1 0.013 15.0 0.1 2.5 1 1 0 1 1 1 1 Caleosin related protein EF-hand_like PF09279.6 AIN96008.1 - 0.00033 20.6 1.2 0.0031 17.5 0.1 2.4 2 1 0 2 2 2 1 Phosphoinositide-specific phospholipase C, efhand-like RNA_pol_Rpb4 PF03874.11 AIN96008.1 - 0.0038 17.2 0.5 1.7 8.6 0.1 2.4 2 0 0 2 2 2 1 RNA polymerase Rpb4 DUF1103 PF06513.6 AIN96008.1 - 0.0051 16.2 1.1 0.0059 16.0 0.8 1.1 1 0 0 1 1 1 1 Repeat of unknown function (DUF1103) MotA_activ PF09114.5 AIN96008.1 - 0.021 14.5 0.1 4.2 7.1 0.0 2.3 2 0 0 2 2 2 0 Transcription factor MotA, activation domain Poly_export PF02563.11 AIN96008.1 - 0.042 13.6 0.2 11 5.8 0.0 3.1 1 1 2 3 3 3 0 Polysaccharide biosynthesis/export protein LNS2 PF08235.8 AIN96008.1 - 0.045 13.3 0.1 0.33 10.4 0.0 1.9 2 0 0 2 2 2 0 LNS2 (Lipin/Ned1/Smp2) Tenui_NCP PF04876.7 AIN96008.1 - 0.064 12.8 0.1 0.95 8.9 0.0 2.1 1 1 1 2 2 2 0 Tenuivirus major non-capsid protein Toprim_2 PF13155.1 AIN96008.1 - 0.065 13.5 0.8 14 6.0 0.3 2.6 1 1 2 3 3 3 0 Toprim-like SpoVIF PF14069.1 AIN96008.1 - 0.077 12.7 0.8 1.6 8.5 0.1 2.6 3 0 0 3 3 3 0 Stage VI sporulation protein F DUF1880 PF08976.6 AIN96008.1 - 0.13 12.3 0.0 0.84 9.7 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF1880) DUF3441 PF11923.3 AIN96009.1 - 4.6e-33 113.1 0.0 1.8e-32 111.2 0.0 2.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3441) FbpA PF05833.6 AIN96009.1 - 1.1e-28 99.9 10.0 1.5e-23 83.0 0.0 2.6 3 0 0 3 3 3 2 Fibronectin-binding protein A N-terminus (FbpA) DUF814 PF05670.8 AIN96009.1 - 1.9e-06 27.6 0.0 9.1e-05 22.2 0.0 2.9 1 1 0 1 1 1 1 Domain of unknown function (DUF814) SLA_LP_auto_ag PF05889.8 AIN96010.1 - 1.7e-91 306.5 0.0 1.8e-50 171.5 0.0 3.4 3 1 0 3 3 3 3 Soluble liver antigen/liver pancreas antigen (SLA/LP autoantigen) Beta_elim_lyase PF01212.16 AIN96010.1 - 0.00051 19.2 0.0 0.00082 18.5 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase Toxin_23 PF08093.6 AIN96010.1 - 9.1 6.3 8.0 0.49 10.3 1.0 2.2 2 0 0 2 2 2 0 Magi 5 toxic peptide family EF1G PF00647.14 AIN96012.1 - 5.5e-47 157.9 0.1 1.8e-46 156.2 0.1 1.8 2 0 0 2 2 2 1 Elongation factor 1 gamma, conserved domain GST_C PF00043.20 AIN96012.1 - 4.6e-12 45.7 0.1 4.6e-12 45.7 0.0 2.1 3 0 0 3 3 3 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 AIN96012.1 - 1.2e-09 38.2 0.0 3.3e-09 36.7 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 AIN96012.1 - 5.2e-05 23.6 0.5 0.00015 22.1 0.1 2.1 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 AIN96012.1 - 6.5e-05 22.7 0.0 0.00016 21.4 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 AIN96012.1 - 0.00016 21.8 0.0 0.00045 20.3 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Ribosomal_60s PF00428.14 AIN96012.1 - 0.19 12.1 5.0 0.51 10.7 3.5 1.7 1 0 0 1 1 1 0 60s Acidic ribosomal protein PAM2 PF07145.10 AIN96013.1 - 0.0024 17.2 3.7 0.0069 15.8 0.0 3.1 3 0 0 3 3 3 1 Ataxin-2 C-terminal region HAUS-augmin3 PF14932.1 AIN96013.1 - 0.021 13.9 0.4 0.071 12.2 0.2 1.9 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 DUF2115 PF09888.4 AIN96013.1 - 0.31 11.1 0.2 34 4.4 0.0 2.5 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2115) Chorein_N PF12624.2 AIN96014.1 - 7.6e-26 89.9 0.0 1.8e-25 88.7 0.0 1.6 1 0 0 1 1 1 1 N-terminal region of Chorein, a TM vesicle-mediated sorter DUF1162 PF06650.7 AIN96014.1 - 0.0097 15.1 0.0 15 4.7 0.0 3.5 3 0 0 3 3 3 2 Protein of unknown function (DUF1162) PUB PF09409.5 AIN96015.1 - 3.7e-13 49.0 0.0 7.1e-13 48.1 0.0 1.5 1 0 0 1 1 1 1 PUB domain zf-CHCC PF10276.4 AIN96015.1 - 0.003 17.3 0.3 0.003 17.3 0.2 2.0 2 0 0 2 2 2 1 Zinc-finger domain OB_RNB PF08206.6 AIN96015.1 - 0.091 12.2 0.1 0.18 11.2 0.0 1.4 1 0 0 1 1 1 0 Ribonuclease B OB domain Phage_integrase PF00589.17 AIN96015.1 - 0.093 12.3 0.2 0.17 11.5 0.0 1.5 2 0 0 2 2 2 0 Phage integrase family zf-C3HC4_3 PF13920.1 AIN96016.1 - 7.8e-11 41.4 12.9 7.8e-11 41.4 8.9 2.4 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) UEV PF05743.8 AIN96016.1 - 4.6e-10 39.2 0.0 9.7e-10 38.1 0.0 1.5 1 0 0 1 1 1 1 UEV domain UQ_con PF00179.21 AIN96016.1 - 0.017 14.5 0.1 0.038 13.4 0.0 1.5 1 1 0 1 1 1 0 Ubiquitin-conjugating enzyme CDC50 PF03381.10 AIN96018.1 - 6.4e-77 258.4 0.2 1.3e-76 257.3 0.0 1.5 2 0 0 2 2 2 1 LEM3 (ligand-effect modulator 3) family / CDC50 family Propeptide_C1 PF08127.8 AIN96018.1 - 0.0043 16.6 0.0 0.011 15.3 0.0 1.7 1 0 0 1 1 1 1 Peptidase family C1 propeptide RNF111_N PF15303.1 AIN96018.1 - 0.28 10.6 9.7 0.45 9.9 6.7 1.2 1 0 0 1 1 1 0 E3 ubiquitin-protein ligase Arkadia N-terminus PTS_EIIB PF00367.15 AIN96019.1 - 0.0031 16.7 0.1 0.0078 15.4 0.0 1.6 1 0 0 1 1 1 1 phosphotransferase system, EIIB SPAM PF02090.10 AIN96019.1 - 0.23 11.4 5.6 0.58 10.1 0.1 2.4 1 1 1 2 2 2 0 Salmonella surface presentation of antigen gene type M protein IncA PF04156.9 AIN96019.1 - 0.39 10.2 10.1 0.13 11.8 4.2 1.9 1 1 1 2 2 2 0 IncA protein CENP-F_leu_zip PF10473.4 AIN96019.1 - 2.5 7.9 10.3 0.61 9.9 1.0 3.0 3 0 0 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Cep57_CLD_2 PF14197.1 AIN96019.1 - 4.7 7.2 10.3 0.57 10.1 1.4 2.9 3 0 0 3 3 3 0 Centrosome localisation domain of PPC89 LCAT PF02450.10 AIN96020.1 - 6.1e-44 150.5 0.0 1.3e-42 146.1 0.0 2.1 1 1 0 1 1 1 1 Lecithin:cholesterol acyltransferase Abhydrolase_6 PF12697.2 AIN96020.1 - 0.0024 17.7 0.1 0.0049 16.7 0.1 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 AIN96020.1 - 0.1 12.3 0.0 0.21 11.3 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase family Motile_Sperm PF00635.21 AIN96021.1 - 3.8e-11 42.5 0.0 6.4e-11 41.8 0.0 1.3 1 0 0 1 1 1 1 MSP (Major sperm protein) domain SHS2_Rpb7-N PF03876.12 AIN96022.1 - 2.7e-24 85.0 0.0 6.2e-24 83.9 0.0 1.6 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 RNA_pol_Rbc25 PF08292.7 AIN96022.1 - 4.1e-10 39.9 0.0 5.1e-05 23.4 0.0 2.1 2 0 0 2 2 2 2 RNA polymerase III subunit Rpc25 SurE PF01975.12 AIN96022.1 - 2.1 7.6 6.4 8.3 5.6 0.1 2.2 2 0 0 2 2 2 0 Survival protein SurE eIF2_C PF09173.6 AIN96023.1 - 1.3e-29 102.1 0.1 2.8e-29 100.9 0.1 1.6 1 0 0 1 1 1 1 Initiation factor eIF2 gamma, C terminal GTP_EFTU_D2 PF03144.20 AIN96023.1 - 3.7e-06 26.9 2.8 8.2e-06 25.8 0.8 2.3 2 0 0 2 2 2 1 Elongation factor Tu domain 2 GTP_EFTU PF00009.22 AIN96023.1 - 4.5e-05 22.9 0.1 7e-05 22.3 0.1 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU PF00009.22 AIN96024.1 - 2.3e-35 121.7 0.1 3.6e-35 121.0 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain eIF2_C PF09173.6 AIN96024.1 - 6.4e-12 45.3 0.1 1.5e-10 40.9 0.0 2.8 3 0 0 3 3 3 1 Initiation factor eIF2 gamma, C terminal GTP_EFTU_D2 PF03144.20 AIN96024.1 - 0.00057 19.9 3.4 0.0032 17.5 0.9 3.0 2 1 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 AIN96024.1 - 0.00086 19.2 0.0 0.0016 18.3 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.18 AIN96024.1 - 0.076 12.8 0.0 0.7 9.6 0.0 2.2 2 0 0 2 2 2 0 Dynamin family Miro PF08477.8 AIN96024.1 - 0.16 12.4 0.0 0.56 10.7 0.0 1.9 1 1 0 1 1 1 0 Miro-like protein DUF4201 PF13870.1 AIN96025.1 - 0.0021 17.5 10.3 0.029 13.7 1.6 2.1 2 0 0 2 2 2 2 Domain of unknown function (DUF4201) CALCOCO1 PF07888.6 AIN96025.1 - 0.0029 15.9 6.9 0.0035 15.7 4.8 1.1 1 0 0 1 1 1 1 Calcium binding and coiled-coil domain (CALCOCO1) like IncA PF04156.9 AIN96025.1 - 0.0048 16.5 12.5 0.012 15.2 7.6 1.9 1 1 1 2 2 2 1 IncA protein Spectrin PF00435.16 AIN96025.1 - 0.007 16.6 12.8 2.1 8.6 5.3 3.1 2 1 1 3 3 3 1 Spectrin repeat WEMBL PF05701.6 AIN96025.1 - 0.015 13.7 12.1 0.025 13.0 8.4 1.2 1 0 0 1 1 1 0 Weak chloroplast movement under blue light Reo_sigmaC PF04582.7 AIN96025.1 - 0.037 13.2 4.3 0.043 13.0 1.3 1.8 1 1 1 2 2 2 0 Reovirus sigma C capsid protein DUF4407 PF14362.1 AIN96025.1 - 0.054 12.4 8.9 0.044 12.7 3.8 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) SpoVAD PF07451.6 AIN96025.1 - 0.064 11.7 0.1 0.087 11.2 0.1 1.1 1 0 0 1 1 1 0 Stage V sporulation protein AD (SpoVAD) TBPIP PF07106.8 AIN96025.1 - 0.16 11.5 10.3 0.32 10.5 2.1 3.1 2 2 1 3 3 3 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Hemerythrin PF01814.18 AIN96025.1 - 0.23 11.6 4.5 1.6 8.8 0.3 2.9 3 0 0 3 3 3 0 Hemerythrin HHE cation binding domain Myosin_tail_1 PF01576.14 AIN96025.1 - 0.28 8.8 14.8 1.4 6.4 10.3 2.0 1 1 0 1 1 1 0 Myosin tail HalX PF08663.5 AIN96025.1 - 0.34 10.9 10.3 2 8.4 0.4 3.6 2 1 2 4 4 4 0 HalX domain DUF4631 PF15450.1 AIN96025.1 - 0.39 8.9 13.9 0.92 7.7 9.6 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4631) DUF1664 PF07889.7 AIN96025.1 - 0.45 10.3 5.3 4.4 7.1 0.4 2.7 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) Rootletin PF15035.1 AIN96025.1 - 0.49 10.3 13.9 0.35 10.8 4.7 2.8 1 1 0 2 2 2 0 Ciliary rootlet component, centrosome cohesion Scaffolding_pro PF11418.3 AIN96025.1 - 0.57 10.5 5.4 2.6 8.3 3.2 2.2 2 1 0 2 2 2 0 Phi29 scaffolding protein DUF904 PF06005.7 AIN96025.1 - 0.63 10.3 15.3 1.5 9.1 1.7 3.6 4 1 1 5 5 4 0 Protein of unknown function (DUF904) Cep57_CLD_2 PF14197.1 AIN96025.1 - 0.82 9.6 12.4 0.16 11.9 1.8 3.2 3 0 0 3 3 3 0 Centrosome localisation domain of PPC89 Microtub_assoc PF07989.6 AIN96025.1 - 0.92 9.3 5.8 5.5 6.8 0.4 2.9 2 0 0 2 2 2 0 Microtubule associated V_ATPase_I PF01496.14 AIN96025.1 - 1.1 7.0 5.9 1.3 6.8 4.1 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Exonuc_VII_L PF02601.10 AIN96025.1 - 1.1 8.4 7.6 1.4 8.0 5.3 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit DivIC PF04977.10 AIN96025.1 - 1.1 8.8 12.4 1.6 8.2 0.9 3.4 3 0 0 3 3 3 0 Septum formation initiator Kinetocho_Slk19 PF12709.2 AIN96025.1 - 1.7 8.8 7.7 6.5 6.9 0.1 3.5 2 1 2 4 4 4 0 Central kinetochore-associated Spc7 PF08317.6 AIN96025.1 - 1.8 7.1 10.2 1.8 7.1 6.1 1.6 1 1 0 1 1 1 0 Spc7 kinetochore protein FliD_N PF02465.13 AIN96025.1 - 1.9 8.9 9.4 7.6 6.9 1.0 2.9 2 1 1 3 3 3 0 Flagellar hook-associated protein 2 N-terminus CCDC-167 PF15188.1 AIN96025.1 - 1.9 8.5 9.4 1 9.3 0.9 3.1 1 1 2 3 3 3 0 Coiled-coil domain-containing protein 167 Mnd1 PF03962.10 AIN96025.1 - 2.3 7.8 15.0 3.5 7.2 2.8 2.7 1 1 1 3 3 3 0 Mnd1 family FUSC PF04632.7 AIN96025.1 - 2.7 6.2 15.3 6.2 5.1 10.6 1.5 1 1 0 1 1 1 0 Fusaric acid resistance protein family AAA_13 PF13166.1 AIN96025.1 - 2.9 6.2 9.1 5.4 5.3 6.3 1.4 1 1 0 1 1 1 0 AAA domain Atg14 PF10186.4 AIN96025.1 - 3.5 6.4 13.8 2.7 6.8 7.4 2.0 1 1 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 DUF4200 PF13863.1 AIN96025.1 - 5.5 6.9 14.3 12 5.8 3.8 2.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) Seryl_tRNA_N PF02403.17 AIN96025.1 - 5.9 6.9 12.7 6.3 6.8 1.0 3.0 2 1 2 4 4 4 0 Seryl-tRNA synthetase N-terminal domain DUF2681 PF10883.3 AIN96025.1 - 6.7 6.9 7.2 5.1 7.3 0.4 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF2681) DUF1151 PF06625.6 AIN96025.1 - 7.8 6.2 12.1 4.4 7.0 0.4 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1151) Occludin_ELL PF07303.8 AIN96025.1 - 7.8 7.2 7.5 6.4 7.5 1.2 2.5 2 1 0 2 2 2 0 Occludin homology domain DUF4570 PF15134.1 AIN96025.1 - 9.7 6.0 11.0 10 6.0 0.4 2.7 1 1 2 3 3 3 0 Domain of unknown function (DUF4570) MRP PF09387.5 AIN96027.1 - 7.7e-65 218.2 0.7 8.8e-65 218.0 0.5 1.0 1 0 0 1 1 1 1 Mitochondrial RNA binding protein MRP DUF362 PF04015.7 AIN96027.1 - 0.1 12.0 0.0 0.14 11.6 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF362) Tim17 PF02466.14 AIN96028.1 - 3.4e-16 59.4 9.4 5e-16 58.9 6.5 1.2 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Cytochrom_B_N PF00033.14 AIN96028.1 - 0.015 14.6 0.9 0.015 14.6 0.7 1.5 2 0 0 2 2 2 0 Cytochrome b(N-terminal)/b6/petB DUF1069 PF06370.6 AIN96028.1 - 0.023 14.0 0.4 0.037 13.4 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1069) DUF3789 PF12664.2 AIN96029.1 - 0.054 12.8 4.3 0.1 11.9 3.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3789) RRM_1 PF00076.17 AIN96031.1 - 0.14 11.7 0.2 0.41 10.3 0.1 1.8 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Skp1 PF01466.14 AIN96032.1 - 8.7e-05 22.4 3.0 0.00054 19.9 2.1 2.1 1 1 0 1 1 1 1 Skp1 family, dimerisation domain Skp1 PF01466.14 AIN96033.1 - 0.019 15.0 0.3 0.17 11.9 0.1 2.5 2 1 0 2 2 2 0 Skp1 family, dimerisation domain CDC45 PF02724.9 AIN96033.1 - 1.9 6.3 4.6 3.4 5.5 3.2 1.3 1 0 0 1 1 1 0 CDC45-like protein Ank PF00023.25 AIN96035.1 - 0.00013 21.5 0.7 0.00071 19.2 0.1 2.6 2 0 0 2 2 2 1 Ankyrin repeat Ank_2 PF12796.2 AIN96035.1 - 0.00041 20.6 0.2 0.005 17.1 0.0 2.7 3 0 0 3 3 3 1 Ankyrin repeats (3 copies) Ank_5 PF13857.1 AIN96035.1 - 0.00078 19.6 3.5 0.0054 16.9 0.1 3.3 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank_4 PF13637.1 AIN96035.1 - 0.0013 19.2 0.1 0.014 15.8 0.0 2.7 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 AIN96035.1 - 0.066 13.4 0.1 0.5 10.7 0.0 2.6 2 0 0 2 2 2 0 Ankyrin repeat zf-C3HC4_3 PF13920.1 AIN96036.1 - 6.8e-10 38.4 22.9 6.8e-10 38.4 15.9 2.7 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 AIN96036.1 - 0.0054 16.7 23.1 0.0054 16.7 16.0 3.3 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) AAA PF00004.24 AIN96037.1 - 1.5e-33 115.8 0.2 1.2e-21 77.3 0.0 3.0 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 AIN96037.1 - 1.3e-09 38.2 0.8 0.00016 21.7 0.0 4.1 3 1 1 4 4 3 1 AAA domain AAA_16 PF13191.1 AIN96037.1 - 1.1e-08 35.3 1.5 5.8e-06 26.4 0.0 3.7 3 1 1 4 4 3 1 AAA ATPase domain AAA_33 PF13671.1 AIN96037.1 - 1.2e-07 31.7 0.0 0.0055 16.5 0.0 3.6 3 0 0 3 3 3 2 AAA domain Zot PF05707.7 AIN96037.1 - 1.3e-07 31.2 0.6 0.044 13.2 0.0 4.0 2 2 1 3 3 3 2 Zonular occludens toxin (Zot) AAA_19 PF13245.1 AIN96037.1 - 3.1e-07 30.0 3.2 0.0004 20.0 0.0 3.8 4 0 0 4 4 3 2 Part of AAA domain AAA_14 PF13173.1 AIN96037.1 - 3.7e-07 30.0 0.0 0.00017 21.5 0.0 2.6 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.12 AIN96037.1 - 7.4e-06 25.4 0.0 0.0034 16.8 0.0 2.6 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_17 PF13207.1 AIN96037.1 - 1.8e-05 25.5 0.0 0.028 15.2 0.0 3.0 2 0 0 2 2 2 1 AAA domain TIP49 PF06068.8 AIN96037.1 - 2.6e-05 23.1 0.1 0.012 14.3 0.0 2.5 2 0 0 2 2 2 1 TIP49 C-terminus AAA_5 PF07728.9 AIN96037.1 - 3.6e-05 23.5 0.0 0.0065 16.2 0.0 3.1 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) DUF2075 PF09848.4 AIN96037.1 - 4.9e-05 22.4 0.1 0.38 9.6 0.0 3.2 2 1 1 3 3 3 2 Uncharacterized conserved protein (DUF2075) RNA_helicase PF00910.17 AIN96037.1 - 5.3e-05 23.3 0.0 0.022 14.9 0.0 2.7 2 0 0 2 2 2 1 RNA helicase ABC_tran PF00005.22 AIN96037.1 - 0.00046 20.5 0.2 0.042 14.1 0.0 3.0 3 0 0 3 3 2 1 ABC transporter AAA_18 PF13238.1 AIN96037.1 - 0.00084 19.6 0.0 0.36 11.1 0.0 2.7 2 0 0 2 2 2 1 AAA domain Torsin PF06309.6 AIN96037.1 - 0.0011 18.7 0.2 0.078 12.8 0.1 2.6 2 0 0 2 2 2 1 Torsin NACHT PF05729.7 AIN96037.1 - 0.0014 18.3 0.2 0.077 12.6 0.0 3.0 2 1 0 2 2 2 1 NACHT domain AAA_30 PF13604.1 AIN96037.1 - 0.0016 18.0 1.7 0.11 12.1 0.1 2.9 3 0 0 3 3 2 1 AAA domain Sigma54_activat PF00158.21 AIN96037.1 - 0.0019 17.7 0.5 0.63 9.4 0.0 2.7 3 0 0 3 3 2 1 Sigma-54 interaction domain AAA_25 PF13481.1 AIN96037.1 - 0.0021 17.5 0.1 0.38 10.1 0.1 2.8 2 0 0 2 2 2 1 AAA domain RuvB_N PF05496.7 AIN96037.1 - 0.0029 16.6 0.0 0.097 11.6 0.0 2.4 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus Bac_DnaA PF00308.13 AIN96037.1 - 0.0036 16.9 0.1 0.016 14.8 0.0 1.9 2 0 0 2 2 2 1 Bacterial dnaA protein Mg_chelatase PF01078.16 AIN96037.1 - 0.0037 16.4 0.3 0.044 12.9 0.1 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI PhoH PF02562.11 AIN96037.1 - 0.004 16.4 1.2 0.094 11.9 0.0 3.0 2 1 1 3 3 3 1 PhoH-like protein Arch_ATPase PF01637.13 AIN96037.1 - 0.0083 15.8 0.0 3.6 7.2 0.0 2.5 2 0 0 2 2 2 1 Archaeal ATPase AAA_2 PF07724.9 AIN96037.1 - 0.02 14.8 0.2 0.16 11.8 0.0 2.5 3 0 0 3 3 3 0 AAA domain (Cdc48 subfamily) APS_kinase PF01583.15 AIN96037.1 - 0.02 14.5 0.1 0.3 10.7 0.0 2.4 2 0 0 2 2 2 0 Adenylylsulphate kinase PIF1 PF05970.9 AIN96037.1 - 0.021 13.7 0.5 1.1 8.1 0.1 2.9 3 0 0 3 3 3 0 PIF1-like helicase AAA_28 PF13521.1 AIN96037.1 - 0.027 14.4 0.0 0.85 9.5 0.0 3.1 3 0 0 3 3 3 0 AAA domain DUF258 PF03193.11 AIN96037.1 - 0.028 13.6 0.0 0.19 10.9 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function, DUF258 AAA_29 PF13555.1 AIN96037.1 - 0.045 13.2 1.1 4.4 6.9 0.1 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain Sigma54_activ_2 PF14532.1 AIN96037.1 - 0.049 13.6 0.0 0.26 11.3 0.0 2.2 2 0 0 2 2 2 0 Sigma-54 interaction domain ResIII PF04851.10 AIN96037.1 - 0.057 13.2 0.0 0.43 10.3 0.0 2.2 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit SRP54 PF00448.17 AIN96037.1 - 0.07 12.5 0.2 0.57 9.5 0.0 2.5 3 0 0 3 3 3 0 SRP54-type protein, GTPase domain AAA_23 PF13476.1 AIN96037.1 - 0.072 13.4 0.1 1.2 9.4 0.0 2.4 2 0 0 2 2 2 0 AAA domain KaiC PF06745.8 AIN96037.1 - 0.08 12.0 0.3 4.9 6.1 0.0 2.5 2 0 0 2 2 2 0 KaiC NB-ARC PF00931.17 AIN96037.1 - 0.11 11.3 0.0 0.27 10.0 0.0 1.6 1 0 0 1 1 1 0 NB-ARC domain AAA_10 PF12846.2 AIN96037.1 - 0.47 9.8 7.5 11 5.3 0.0 4.0 3 2 2 5 5 4 0 AAA-like domain AAA_12 PF13087.1 AIN96039.1 - 7.6e-49 165.8 0.0 1.4e-48 164.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 AIN96039.1 - 2.4e-38 132.0 0.2 1.2e-37 129.7 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 AIN96039.1 - 3.9e-06 26.5 0.2 3.9e-06 26.5 0.1 2.7 2 0 0 2 2 2 1 Part of AAA domain AAA_22 PF13401.1 AIN96039.1 - 0.0012 19.0 0.0 0.046 13.8 0.0 3.1 2 0 0 2 2 2 1 AAA domain ResIII PF04851.10 AIN96039.1 - 0.004 17.0 0.0 0.086 12.6 0.0 2.3 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit UvrD-helicase PF00580.16 AIN96039.1 - 0.027 13.7 0.6 0.35 10.1 0.0 2.6 3 0 0 3 3 3 0 UvrD/REP helicase N-terminal domain DUF2075 PF09848.4 AIN96039.1 - 0.12 11.2 0.0 4 6.3 0.0 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) PhoH PF02562.11 AIN96039.1 - 0.14 11.4 0.0 14 4.8 0.0 2.4 2 0 0 2 2 2 0 PhoH-like protein Bromodomain PF00439.20 AIN96041.1 - 3.9e-21 74.7 0.0 1.6e-10 40.7 0.0 2.3 2 0 0 2 2 2 2 Bromodomain Mito_carr PF00153.22 AIN96042.1 - 1.6e-44 149.5 7.7 1.1e-17 63.5 0.1 3.8 3 1 0 3 3 3 3 Mitochondrial carrier protein CytB6-F_Fe-S PF08802.5 AIN96042.1 - 0.32 11.0 4.3 0.41 10.6 0.1 2.8 2 0 0 2 2 2 0 Cytochrome B6-F complex Fe-S subunit Orthopox_C10L PF07020.6 AIN96042.1 - 2 8.9 8.4 1.1 9.8 3.2 2.1 2 0 0 2 2 2 0 Orthopoxvirus C10L protein zf-FPG_IleRS PF06827.9 AIN96043.1 - 0.018 14.6 0.5 6.1 6.5 0.0 2.8 2 0 0 2 2 2 0 Zinc finger found in FPG and IleRS DZR PF12773.2 AIN96043.1 - 0.028 14.2 3.1 0.52 10.1 0.1 3.0 2 1 0 2 2 2 0 Double zinc ribbon DUF3279 PF11682.3 AIN96043.1 - 0.15 11.6 0.6 2.8 7.5 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3279) Mu-like_Com PF10122.4 AIN96043.1 - 0.98 8.5 4.7 7.5 5.6 0.0 3.1 3 0 0 3 3 3 0 Mu-like prophage protein Com Kelch_3 PF13415.1 AIN96044.1 - 8.3e-07 29.0 0.4 0.023 14.8 0.0 3.5 3 0 0 3 3 3 2 Galactose oxidase, central domain Kelch_4 PF13418.1 AIN96044.1 - 2.6e-06 27.0 0.1 0.29 10.9 0.0 3.4 3 0 0 3 3 3 3 Galactose oxidase, central domain Kelch_5 PF13854.1 AIN96044.1 - 0.00035 20.4 3.9 0.081 12.9 0.3 3.1 2 1 0 2 2 2 2 Kelch motif Gly-rich_Ago1 PF12764.2 AIN96044.1 - 0.11 13.1 0.5 0.11 13.1 0.4 2.2 2 0 0 2 2 2 0 Glycine-rich region of argonaut Peptidase_C97 PF05903.9 AIN96045.1 - 6.1e-21 74.7 0.1 1.6e-20 73.4 0.0 1.6 1 1 1 2 2 2 1 PPPDE putative peptidase domain Flagellar_rod PF05149.7 AIN96047.1 - 2.9e-92 308.9 18.1 2.9e-92 308.9 12.5 1.8 2 0 0 2 2 2 1 Paraflagellar rod protein HHH_3 PF12836.2 AIN96048.1 - 0.11 12.4 0.0 0.23 11.4 0.0 1.4 1 0 0 1 1 1 0 Helix-hairpin-helix motif Histone PF00125.19 AIN96049.1 - 1.7e-16 60.0 1.4 2.6e-16 59.4 1.0 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 AIN96049.1 - 0.00025 21.0 0.2 0.00053 19.9 0.1 1.6 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone NAAA-beta PF15508.1 AIN96051.1 - 0.099 12.9 0.1 0.18 12.1 0.0 1.3 1 0 0 1 1 1 0 beta subunit of N-acylethanolamine-hydrolyzing acid amidase F-box PF00646.28 AIN96053.1 - 0.034 13.7 0.0 0.11 12.2 0.0 1.8 1 0 0 1 1 1 0 F-box domain MBOAT PF03062.14 AIN96053.1 - 0.042 12.9 4.4 0.18 10.8 0.2 2.4 2 1 0 2 2 2 0 MBOAT, membrane-bound O-acyltransferase family Glyco_hydro_47 PF01532.15 AIN96054.1 - 1.4e-07 30.5 0.0 2.9e-07 29.5 0.0 1.4 2 0 0 2 2 2 1 Glycosyl hydrolase family 47 PBP_like PF12727.2 AIN96054.1 - 0.043 12.7 0.2 0.16 10.8 0.0 2.0 2 0 0 2 2 2 0 PBP superfamily domain SET PF00856.23 AIN96055.1 - 4.5e-09 36.8 0.0 1.7e-08 34.9 0.0 2.0 2 0 0 2 2 2 1 SET domain Trigger_C PF05698.9 AIN96056.1 - 0.0024 17.7 5.4 0.0075 16.1 3.6 2.1 1 1 0 1 1 1 1 Bacterial trigger factor protein (TF) C-terminus CENP-N PF05238.8 AIN96056.1 - 0.0048 16.0 4.5 0.0057 15.7 3.1 1.0 1 0 0 1 1 1 1 Kinetochore protein CHL4 like Med8 PF10232.4 AIN96056.1 - 0.0092 15.5 5.9 0.011 15.2 4.1 1.2 1 0 0 1 1 1 1 Mediator of RNA polymerase II transcription complex subunit 8 SurA_N PF09312.6 AIN96056.1 - 0.039 13.8 1.7 0.069 13.0 0.9 1.8 1 1 0 1 1 1 0 SurA N-terminal domain Cauli_AT PF03233.8 AIN96056.1 - 0.36 10.5 4.0 0.65 9.6 2.8 1.4 1 0 0 1 1 1 0 Aphid transmission protein DUF1664 PF07889.7 AIN96056.1 - 0.45 10.3 6.0 0.65 9.8 2.5 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) LemA PF04011.7 AIN96056.1 - 0.76 8.8 5.0 1.7 7.7 3.6 1.5 1 1 1 2 2 2 0 LemA family DUF4570 PF15134.1 AIN96056.1 - 0.86 9.4 7.8 0.037 13.8 1.3 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4570) DUF1128 PF06569.6 AIN96056.1 - 0.91 9.2 5.4 3.2 7.5 0.0 2.7 3 1 0 3 3 3 0 Protein of unknown function (DUF1128) DUF3647 PF12363.3 AIN96056.1 - 1.3 9.1 6.9 6.6 6.8 1.5 2.1 1 1 1 2 2 2 0 Phage protein DUF4407 PF14362.1 AIN96056.1 - 2.1 7.2 7.7 3 6.7 5.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) V_ATPase_I PF01496.14 AIN96056.1 - 2.4 5.9 6.0 2.6 5.7 4.1 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Upf2 PF04050.9 AIN96056.1 - 3.2 7.5 14.1 97 2.6 9.8 2.0 1 1 0 1 1 1 0 Up-frameshift suppressor 2 HSCB_C PF07743.8 AIN96056.1 - 6.1 7.3 11.3 2.8 8.4 2.2 3.1 1 1 2 3 3 3 0 HSCB C-terminal oligomerisation domain Coq4 PF05019.8 AIN96057.1 - 2.5e-54 183.5 0.0 2.8e-54 183.3 0.0 1.0 1 0 0 1 1 1 1 Coenzyme Q (ubiquinone) biosynthesis protein Coq4 DnaJ PF00226.26 AIN96058.1 - 1.8e-12 46.7 0.1 3.4e-12 45.9 0.1 1.4 1 0 0 1 1 1 1 DnaJ domain GcrA PF07750.6 AIN96058.1 - 0.0097 16.1 0.0 0.02 15.1 0.0 1.5 1 0 0 1 1 1 1 GcrA cell cycle regulator Rhodanese PF00581.15 AIN96059.1 - 0.0023 18.2 0.0 0.0029 17.9 0.0 1.2 1 0 0 1 1 1 1 Rhodanese-like domain Rhodanese PF00581.15 AIN96060.1 - 5.5e-14 52.4 0.0 7e-14 52.1 0.0 1.1 1 0 0 1 1 1 1 Rhodanese-like domain Rhodanese PF00581.15 AIN96061.1 - 1.1e-18 67.5 0.0 1.4e-18 67.3 0.0 1.1 1 0 0 1 1 1 1 Rhodanese-like domain Mito_carr PF00153.22 AIN96061.1 - 0.14 11.8 0.0 0.22 11.2 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial carrier protein Tet_JBP PF12851.2 AIN96062.1 - 3.7e-23 81.6 0.0 6.8e-23 80.8 0.0 1.5 1 0 0 1 1 1 1 Oxygenase domain of the 2OGFeDO superfamily Cyt-b5 PF00173.23 AIN96063.1 - 2.4e-19 68.8 0.3 3.1e-19 68.5 0.2 1.1 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Laminin_G_3 PF13385.1 AIN96065.1 - 1.4e-05 25.3 0.0 0.00039 20.7 0.0 2.3 2 0 0 2 2 2 1 Concanavalin A-like lectin/glucanases superfamily Laminin_G_2 PF02210.19 AIN96065.1 - 0.00013 21.9 0.1 0.48 10.4 0.0 2.8 2 0 0 2 2 2 2 Laminin G domain UPF0180 PF03698.8 AIN96065.1 - 0.088 12.6 0.0 0.22 11.3 0.0 1.6 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0180) LRR_6 PF13516.1 AIN96066.1 - 5.9e-12 44.3 0.9 0.085 12.9 0.1 6.5 7 0 0 7 7 7 3 Leucine Rich repeat LRR_4 PF12799.2 AIN96066.1 - 0.0053 16.3 0.0 0.36 10.5 0.0 2.9 1 1 2 3 3 3 2 Leucine Rich repeats (2 copies) EF-hand_7 PF13499.1 AIN96067.1 - 0.013 15.6 0.0 0.021 14.9 0.0 1.4 1 0 0 1 1 1 0 EF-hand domain pair EF-hand_1 PF00036.27 AIN96067.1 - 0.019 14.2 0.0 0.05 12.9 0.0 1.7 1 0 0 1 1 1 0 EF hand EF-hand_6 PF13405.1 AIN96067.1 - 0.02 14.7 0.0 0.078 12.9 0.0 2.1 1 1 0 1 1 1 0 EF-hand domain RIIa PF02197.12 AIN96067.1 - 0.041 13.3 0.0 0.084 12.3 0.0 1.5 1 0 0 1 1 1 0 Regulatory subunit of type II PKA R-subunit CENP-F_leu_zip PF10473.4 AIN96068.1 - 0.087 12.6 95.1 0.035 13.9 14.1 7.2 3 1 4 7 7 7 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 CCDC155 PF14662.1 AIN96068.1 - 0.16 11.5 96.1 0.028 14.0 13.2 5.5 2 2 3 5 5 5 0 Coiled-coil region of CCDC155 ADIP PF11559.3 AIN96068.1 - 0.26 11.1 99.5 0.047 13.5 12.1 8.1 2 2 5 8 8 8 0 Afadin- and alpha -actinin-Binding Gryzun PF07919.7 AIN96070.1 - 3.2e-39 134.6 0.0 4.3e-39 134.2 0.0 1.1 1 0 0 1 1 1 1 Gryzun, putative trafficking through Golgi MMS19_N PF14500.1 AIN96071.1 - 9.2e-32 110.3 3.3 2.1e-31 109.1 2.3 1.6 1 0 0 1 1 1 1 Dos2-interacting transcription regulator of RNA-Pol-II CLASP_N PF12348.3 AIN96071.1 - 0.0027 17.1 0.4 0.0082 15.5 0.3 1.8 1 0 0 1 1 1 1 CLASP N terminal Thymidylate_kin PF02223.12 AIN96072.1 - 9.3e-14 51.2 0.0 2.8e-13 49.6 0.0 1.9 1 1 0 1 1 1 1 Thymidylate kinase Rota_NSP4 PF01452.11 AIN96072.1 - 0.07 12.4 0.1 0.1 11.9 0.1 1.2 1 0 0 1 1 1 0 Rotavirus non structural protein Ribosomal_L35Ae PF01247.13 AIN96073.1 - 2.9e-34 116.6 1.4 4.3e-34 116.1 0.9 1.2 1 0 0 1 1 1 1 Ribosomal protein L35Ae RimM PF01782.13 AIN96073.1 - 5.2e-05 23.0 0.2 0.07 13.0 0.0 2.4 2 1 0 2 2 2 2 RimM N-terminal domain adh_short PF00106.20 AIN96075.1 - 1.4e-15 57.5 0.2 4.3e-15 56.0 0.0 1.9 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.1 AIN96075.1 - 6e-05 22.9 0.0 9.2e-05 22.3 0.0 1.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 AIN96075.1 - 0.0002 21.0 0.0 0.00041 20.0 0.0 1.5 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 AIN96075.1 - 0.00046 19.7 0.0 0.00079 18.9 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 AIN96075.1 - 0.096 12.6 0.1 0.47 10.4 0.0 2.2 3 0 0 3 3 3 0 NADH(P)-binding SRP40_C PF05022.7 AIN96076.1 - 3.4e-07 30.6 0.5 8.3e-07 29.4 0.3 1.7 1 0 0 1 1 1 1 SRP40, C-terminal domain Hid1 PF12722.2 AIN96076.1 - 2.2 5.8 3.8 2.6 5.6 2.6 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein WD40 PF00400.27 AIN96077.1 - 4e-47 156.4 32.0 6.4e-11 41.6 0.9 7.5 7 1 0 7 7 7 7 WD domain, G-beta repeat PSP1 PF04468.7 AIN96078.1 - 2.2e-24 85.2 0.4 3.5e-24 84.5 0.3 1.3 1 0 0 1 1 1 1 PSP1 C-terminal conserved region Pex19 PF04614.7 AIN96079.1 - 0.25 10.9 7.7 0.065 12.8 3.2 1.7 2 0 0 2 2 2 0 Pex19 protein family Seryl_tRNA_N PF02403.17 AIN96079.1 - 6.8 6.7 17.7 0.051 13.5 4.0 2.8 2 1 0 3 3 3 0 Seryl-tRNA synthetase N-terminal domain DEAD PF00270.24 AIN96080.1 - 6.6e-12 45.2 0.2 1.3e-08 34.4 0.0 2.6 3 0 0 3 3 3 2 DEAD/DEAH box helicase Helicase_C PF00271.26 AIN96080.1 - 3.2e-11 42.9 0.0 8.9e-11 41.4 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF1253 PF06862.7 AIN96080.1 - 0.003 16.0 0.3 0.45 8.8 0.0 3.3 4 0 0 4 4 4 1 Protein of unknown function (DUF1253) Fer4_19 PF06902.6 AIN96080.1 - 0.02 14.6 0.0 0.057 13.2 0.0 1.8 1 0 0 1 1 1 0 Divergent 4Fe-4S mono-cluster LMP PF04778.7 AIN96082.1 - 0.067 12.9 5.1 0.11 12.3 0.7 2.8 2 1 0 2 2 2 0 LMP repeated region Spc7 PF08317.6 AIN96082.1 - 0.26 9.9 25.4 0.014 14.0 11.3 2.1 2 0 0 2 2 2 0 Spc7 kinetochore protein Sin3_corepress PF08295.7 AIN96082.1 - 3.9 7.2 12.4 0.072 12.8 2.1 2.7 3 1 0 3 3 3 0 Sin3 family co-repressor Phage_GPO PF05929.6 AIN96082.1 - 6.9 5.8 17.8 0.82 8.8 5.2 2.3 2 0 0 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase HI0933_like PF03486.9 AIN96082.1 - 7 5.0 8.3 3.8 5.8 0.2 2.2 2 0 0 2 2 2 0 HI0933-like protein Baculo_PP31 PF05311.6 AIN96082.1 - 8.6 5.5 9.9 0.63 9.2 1.0 2.3 2 1 0 2 2 2 0 Baculovirus 33KDa late protein (PP31) GDA1_CD39 PF01150.12 AIN96083.1 - 1.9e-60 204.5 0.0 1.1e-59 202.1 0.0 1.9 1 1 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family DUF4654 PF15547.1 AIN96083.1 - 0.18 12.1 1.3 0.5 10.6 0.9 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4654) LRR_4 PF12799.2 AIN96084.1 - 1.9e-17 62.4 6.5 2.8e-06 26.8 0.2 3.3 3 0 0 3 3 3 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 AIN96084.1 - 2.6e-12 46.3 10.3 6e-07 29.1 1.5 2.4 1 1 1 2 2 2 2 Leucine rich repeat LRR_1 PF00560.28 AIN96084.1 - 1.3e-09 36.7 8.7 2.5 8.4 0.0 6.2 7 0 0 7 7 7 4 Leucine Rich Repeat LRR_7 PF13504.1 AIN96084.1 - 1.1e-07 30.8 8.3 2.7 8.5 0.0 5.6 5 0 0 5 5 5 4 Leucine rich repeat LRR_6 PF13516.1 AIN96084.1 - 0.00014 21.5 7.1 10 6.5 0.0 5.3 5 0 0 5 5 5 1 Leucine Rich repeat PDZ PF00595.19 AIN96085.1 - 5.7e-06 26.4 0.0 1.2e-05 25.3 0.0 1.5 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) PDZ_2 PF13180.1 AIN96085.1 - 0.00063 19.5 0.0 0.0015 18.3 0.0 1.6 1 0 0 1 1 1 1 PDZ domain MORN PF02493.15 AIN96086.1 - 1.7e-19 68.3 16.8 7.5e-07 28.5 0.4 4.6 4 0 0 4 4 4 4 MORN repeat Pkinase PF00069.20 AIN96087.1 - 5.3e-60 202.7 0.0 6.8e-60 202.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AIN96087.1 - 8.7e-29 100.3 0.0 1.8e-28 99.3 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 AIN96087.1 - 2.7e-06 26.5 0.6 5.2e-06 25.6 0.4 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 AIN96087.1 - 0.00036 20.3 1.7 0.00083 19.1 1.2 1.8 1 1 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.17 AIN96087.1 - 0.027 13.8 1.2 0.15 11.3 0.2 2.3 2 0 0 2 2 2 0 RIO1 family Choline_kinase PF01633.15 AIN96087.1 - 0.11 12.0 0.3 0.21 11.1 0.2 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase Nop PF01798.13 AIN96088.1 - 1.4e-55 186.6 0.2 2.5e-55 185.8 0.1 1.4 1 0 0 1 1 1 1 Putative snoRNA binding domain NOSIC PF08060.8 AIN96088.1 - 3.5e-22 77.9 0.0 6.8e-22 77.0 0.0 1.5 1 0 0 1 1 1 1 NOSIC (NUC001) domain NOP5NT PF08156.8 AIN96088.1 - 1.7e-20 72.9 0.0 4.8e-20 71.4 0.0 1.8 1 0 0 1 1 1 1 NOP5NT (NUC127) domain Amastin PF07344.6 AIN96091.1 - 1.9e-39 134.7 21.4 1.2e-26 93.1 4.7 2.4 2 1 0 2 2 2 2 Amastin surface glycoprotein DUF4653 PF15546.1 AIN96091.1 - 0.041 13.1 0.1 0.059 12.6 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4653) Claudin_2 PF13903.1 AIN96091.1 - 0.071 12.7 31.2 0.44 10.2 6.9 3.4 1 1 2 3 3 3 0 PMP-22/EMP/MP20/Claudin tight junction Vma12 PF11712.3 AIN96091.1 - 1.8 8.2 0.0 1.8 8.2 0.0 3.5 4 0 0 4 4 4 0 Endoplasmic reticulum-based factor for assembly of V-ATPase Amastin PF07344.6 AIN96092.1 - 3e-53 179.5 28.7 1.9e-27 95.8 3.7 2.1 2 0 0 2 2 2 2 Amastin surface glycoprotein TadE PF07811.7 AIN96092.1 - 0.025 14.4 2.7 0.025 14.4 1.9 3.0 3 0 0 3 3 3 0 TadE-like protein Lig_chan PF00060.21 AIN96092.1 - 0.053 13.2 3.1 2 8.1 0.4 2.7 2 1 0 2 2 2 0 Ligand-gated ion channel IFT20 PF14931.1 AIN96093.1 - 4.3 7.2 24.5 0.064 13.1 3.1 3.8 3 1 1 4 4 4 0 Intraflagellar transport complex B, subunit 20 Pterin_4a PF01329.14 AIN96094.1 - 4e-08 32.9 0.0 9.3e-07 28.5 0.0 2.2 1 1 1 2 2 2 1 Pterin 4 alpha carbinolamine dehydratase COPI_assoc PF08507.5 AIN96095.1 - 4.7e-10 39.2 13.6 6e-10 38.9 9.4 1.0 1 0 0 1 1 1 1 COPI associated protein VKOR PF07884.9 AIN96095.1 - 1.2 8.9 9.3 0.89 9.4 4.8 1.7 1 1 1 2 2 2 0 Vitamin K epoxide reductase family DUF2668 PF10873.3 AIN96095.1 - 3.7 7.6 5.3 5.5 7.1 3.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2668) RNase_T PF00929.19 AIN96096.1 - 6e-19 68.9 0.0 1e-18 68.1 0.0 1.4 1 0 0 1 1 1 1 Exonuclease DUF4551 PF15087.1 AIN96096.1 - 2.2 6.5 4.2 3.9 5.7 2.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) FlaC_arch PF05377.6 AIN96097.1 - 0.84 9.5 0.4 2.3 8.1 0.3 1.7 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) Iso_dh PF00180.15 AIN96098.1 - 1.8e-71 240.9 0.0 2e-71 240.7 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase SlyX PF04102.7 AIN96099.1 - 0.018 15.4 7.0 0.018 15.4 4.9 4.2 5 0 0 5 5 5 0 SlyX DUF3584 PF12128.3 AIN96099.1 - 0.072 10.4 14.0 0.1 9.8 9.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DUF2615 PF11027.3 AIN96099.1 - 0.096 12.6 0.3 4 7.4 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2615) V_ATPase_I PF01496.14 AIN96099.1 - 0.28 8.9 5.3 0.38 8.5 3.7 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Sugarporin_N PF11471.3 AIN96099.1 - 0.33 10.6 4.9 1.1 8.9 3.4 1.9 1 1 0 1 1 1 0 Maltoporin periplasmic N-terminal extension DASH_Spc34 PF08657.5 AIN96099.1 - 2.8 7.5 10.8 1.5 8.4 3.6 2.5 1 1 1 2 2 2 0 DASH complex subunit Spc34 Mnd1 PF03962.10 AIN96099.1 - 5.1 6.7 10.9 13 5.4 7.6 1.6 1 1 0 1 1 1 0 Mnd1 family Spc24 PF08286.6 AIN96099.1 - 6.9 6.4 10.1 0.82 9.3 3.6 2.0 2 1 0 2 2 2 0 Spc24 subunit of Ndc80 Sec23_trunk PF04811.10 AIN96100.1 - 2.9e-40 138.1 0.0 7.2e-37 127.0 0.0 2.2 1 1 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.10 AIN96100.1 - 1.6e-25 88.4 0.0 5.5e-25 86.7 0.0 2.0 2 0 0 2 2 2 1 Sec23/Sec24 helical domain Sec23_BS PF08033.7 AIN96100.1 - 4.5e-18 65.5 0.2 1.1e-17 64.2 0.0 1.8 2 0 0 2 2 2 1 Sec23/Sec24 beta-sandwich domain Gelsolin PF00626.17 AIN96100.1 - 6.5e-06 25.7 0.0 1.3e-05 24.7 0.0 1.5 1 0 0 1 1 1 1 Gelsolin repeat zf-Sec23_Sec24 PF04810.10 AIN96100.1 - 0.0088 15.5 6.2 0.02 14.4 4.3 1.6 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Abhydrolase_1 PF00561.15 AIN96101.1 - 0.001 18.6 0.8 0.0027 17.3 0.0 2.0 2 0 0 2 2 2 1 alpha/beta hydrolase fold JAB PF01398.16 AIN96102.1 - 0.0088 15.7 0.0 0.026 14.2 0.0 1.8 1 1 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease BT1 PF03092.11 AIN96103.1 - 1.4e-192 640.2 4.0 1.6e-192 640.0 2.8 1.0 1 0 0 1 1 1 1 BT1 family BT1 PF03092.11 AIN96104.1 - 6.4e-194 644.6 7.5 7.4e-194 644.4 5.2 1.0 1 0 0 1 1 1 1 BT1 family Dak1 PF02733.12 AIN96105.1 - 1.6e-85 286.5 2.0 2.5e-85 285.9 1.4 1.2 1 0 0 1 1 1 1 Dak1 domain Dak2 PF02734.12 AIN96105.1 - 5.8e-37 127.0 3.0 5.8e-37 127.0 2.1 1.8 2 0 0 2 2 2 1 DAK2 domain zf-C3HC4_3 PF13920.1 AIN96107.1 - 1.3e-09 37.5 11.0 1.3e-09 37.5 7.6 1.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 AIN96107.1 - 0.038 14.0 10.4 0.088 12.8 7.2 1.7 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 AIN96107.1 - 0.26 11.0 15.9 0.031 13.9 8.1 1.7 2 1 0 2 2 2 0 zinc-RING finger domain zf-RING_2 PF13639.1 AIN96107.1 - 2.2 8.1 13.1 1.5 8.7 7.7 1.7 2 0 0 2 2 2 0 Ring finger domain zf-C3HC4_3 PF13920.1 AIN96108.1 - 4.7e-10 38.9 12.2 7.8e-10 38.2 8.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 AIN96108.1 - 0.05 13.6 13.7 0.12 12.3 9.5 1.7 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 AIN96108.1 - 0.051 13.3 13.3 0.12 12.0 9.2 1.6 1 1 0 1 1 1 0 zinc-RING finger domain 4F5 PF04419.9 AIN96109.1 - 3e-08 34.2 6.4 3e-08 34.2 4.4 1.5 2 0 0 2 2 2 1 4F5 protein family zf-met2 PF12907.2 AIN96109.1 - 8.9e-06 25.5 0.1 8.9e-06 25.5 0.1 1.8 2 0 0 2 2 2 1 Zinc-binding zf-C2H2_4 PF13894.1 AIN96109.1 - 0.0089 16.2 3.3 0.02 15.2 0.1 2.5 3 0 0 3 3 3 1 C2H2-type zinc finger zf-H2C2_2 PF13465.1 AIN96109.1 - 0.013 15.7 2.6 0.19 12.1 0.2 2.4 2 0 0 2 2 2 0 Zinc-finger double domain Pap_E4 PF02711.9 AIN96109.1 - 0.19 12.5 0.8 0.24 12.2 0.5 1.2 1 0 0 1 1 1 0 E4 protein Peptidase_M8 PF01457.11 AIN96110.1 - 1.7e-258 858.2 0.9 1.9e-258 858.0 0.6 1.0 1 0 0 1 1 1 1 Leishmanolysin Peptidase_M8 PF01457.11 AIN96111.1 - 5.7e-237 787.1 2.1 6.6e-237 786.9 1.5 1.0 1 0 0 1 1 1 1 Leishmanolysin Peptidase_M8 PF01457.11 AIN96112.1 - 2.2e-214 712.6 0.0 2.4e-214 712.4 0.0 1.0 1 0 0 1 1 1 1 Leishmanolysin Reprolysin_2 PF13574.1 AIN96112.1 - 0.15 12.0 0.0 0.27 11.2 0.0 1.3 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Reprolysin_3 PF13582.1 AIN96112.1 - 0.16 12.5 0.0 0.32 11.5 0.0 1.4 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Peptidase_M8 PF01457.11 AIN96113.1 - 2.1e-232 772.1 0.6 2.3e-232 771.9 0.4 1.0 1 0 0 1 1 1 1 Leishmanolysin Pkinase PF00069.20 AIN96114.1 - 7.5e-65 218.6 0.0 8.8e-65 218.4 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AIN96114.1 - 3.1e-28 98.5 0.0 3e-27 95.3 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 AIN96114.1 - 0.0045 16.0 0.0 0.0075 15.3 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 AIN96114.1 - 0.007 15.3 0.0 0.011 14.7 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Baculo_11_kDa PF06143.6 AIN96115.1 - 0.22 10.8 0.6 0.47 9.8 0.4 1.5 1 0 0 1 1 1 0 Baculovirus 11 kDa family DUF2019 PF09450.5 AIN96115.1 - 7.1 6.5 0.0 15 5.5 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF2019) NAD_Gly3P_dh_C PF07479.9 AIN96116.1 - 1.6e-48 164.1 1.1 2.2e-48 163.7 0.2 1.6 2 0 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus NAD_Gly3P_dh_N PF01210.18 AIN96116.1 - 1.1e-46 158.4 0.1 1.7e-46 157.8 0.0 1.3 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus UDPG_MGDP_dh_N PF03721.9 AIN96116.1 - 2.4e-06 27.0 0.1 4.8e-06 26.0 0.1 1.5 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain F420_oxidored PF03807.12 AIN96116.1 - 0.00065 20.0 0.0 0.0014 18.9 0.0 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent DUF1188 PF06690.6 AIN96116.1 - 0.0017 17.5 0.0 0.0036 16.4 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1188) 3HCDH_N PF02737.13 AIN96116.1 - 0.0063 16.1 0.0 0.012 15.2 0.0 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_2 PF03446.10 AIN96116.1 - 0.014 15.2 0.1 0.043 13.6 0.0 1.9 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase TRAPP PF04051.11 AIN96116.1 - 0.07 12.6 0.0 7.8 6.0 0.0 2.2 2 0 0 2 2 2 0 Transport protein particle (TRAPP) component PhrC_PhrF PF11131.3 AIN96116.1 - 0.093 12.3 0.4 0.64 9.6 0.1 2.4 2 0 0 2 2 2 0 Rap-phr extracellular signalling ApbA PF02558.11 AIN96116.1 - 0.1 12.0 0.0 0.18 11.1 0.0 1.5 1 1 0 1 1 1 0 Ketopantoate reductase PanE/ApbA GTP_EFTU PF00009.22 AIN96118.1 - 0.0036 16.7 0.3 0.025 14.0 0.0 2.6 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain Amidinotransf PF02274.12 AIN96120.1 - 0.013 14.6 0.0 0.018 14.1 0.0 1.2 1 0 0 1 1 1 0 Amidinotransferase ADH_zinc_N PF00107.21 AIN96121.1 - 6.2e-15 54.9 0.0 1.1e-14 54.1 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 AIN96121.1 - 2.9e-09 36.6 0.1 1.7e-08 34.1 0.1 2.2 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 AIN96121.1 - 8.6e-07 29.8 0.0 1.7e-06 28.9 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.21 AIN96122.1 - 6.3e-16 58.1 1.5 8.4e-16 57.6 0.0 1.9 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 AIN96122.1 - 2.3e-12 47.9 0.1 7.4e-12 46.2 0.0 1.9 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 AIN96122.1 - 1.2e-06 28.1 0.1 1.1e-05 25.1 0.0 2.5 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain CAF1A PF12253.3 AIN96123.1 - 4.9e-07 29.7 4.8 4.9e-07 29.7 3.3 3.7 3 1 0 3 3 3 1 Chromatin assembly factor 1 subunit A Borrelia_P83 PF05262.6 AIN96123.1 - 4.5 5.4 23.5 0.047 11.9 9.4 2.0 2 0 0 2 2 2 0 Borrelia P83/100 protein ABC1 PF03109.11 AIN96125.1 - 3.3e-22 78.7 0.0 6.7e-22 77.6 0.0 1.5 1 0 0 1 1 1 1 ABC1 family Endonuclease_NS PF01223.18 AIN96126.1 - 8.1e-46 156.2 0.0 1.4e-45 155.5 0.0 1.4 1 0 0 1 1 1 1 DNA/RNA non-specific endonuclease Endonuclea_NS_2 PF13930.1 AIN96126.1 - 0.069 13.1 0.1 0.19 11.7 0.1 1.6 1 1 0 1 1 1 0 DNA/RNA non-specific endonuclease zf-CCCH PF00642.19 AIN96129.1 - 0.00078 19.0 3.6 0.0014 18.2 2.5 1.3 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Mito_fiss_reg PF05308.6 AIN96129.1 - 0.075 12.3 0.1 0.11 11.9 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial fission regulator NAM-associated PF14303.1 AIN96132.1 - 0.001 19.3 3.2 0.0013 19.0 2.2 1.1 1 0 0 1 1 1 1 No apical meristem-associated C-terminal domain DUF1751 PF08551.5 AIN96132.1 - 0.0013 19.0 1.0 0.0073 16.6 0.2 2.2 2 0 0 2 2 2 1 Eukaryotic integral membrane protein (DUF1751) CDC45 PF02724.9 AIN96132.1 - 0.026 12.5 1.8 0.034 12.1 1.2 1.1 1 0 0 1 1 1 0 CDC45-like protein Sec62 PF03839.11 AIN96132.1 - 0.11 11.8 0.5 0.17 11.2 0.4 1.2 1 0 0 1 1 1 0 Translocation protein Sec62 HEAT PF02985.17 AIN96133.1 - 4.5e-10 38.7 34.6 0.0025 17.7 0.1 9.4 9 0 0 9 9 9 6 HEAT repeat HEAT_2 PF13646.1 AIN96133.1 - 0.056 13.7 0.0 0.056 13.7 0.0 9.5 11 2 0 11 11 11 0 HEAT repeats Vac14_Fab1_bd PF12755.2 AIN96133.1 - 0.06 13.7 0.1 0.96 9.8 0.0 3.0 4 0 0 4 4 4 0 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.1 AIN96133.1 - 0.083 13.4 0.1 0.083 13.4 0.0 9.0 9 0 0 9 9 9 0 HEAT-like repeat RRM_1 PF00076.17 AIN96134.1 - 5e-42 141.3 0.2 6.2e-16 57.7 0.0 6.1 5 1 0 5 5 5 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 AIN96134.1 - 2.6e-38 129.8 0.1 1.1e-13 50.9 0.0 5.7 6 0 0 6 6 6 5 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 AIN96134.1 - 9.6e-18 63.7 0.1 1.1e-07 31.5 0.0 4.9 5 0 0 5 5 5 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 AIN96134.1 - 0.023 14.4 0.0 0.91 9.3 0.0 2.9 3 0 0 3 3 3 0 Nup53/35/40-type RNA recognition motif Aa_trans PF01490.13 AIN96135.1 - 5.4e-39 133.8 34.2 6.7e-39 133.5 23.7 1.2 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein DUF1700 PF08006.6 AIN96135.1 - 0.021 14.1 0.2 0.021 14.1 0.1 3.3 3 1 0 3 3 3 0 Protein of unknown function (DUF1700) dCMP_cyt_deam_1 PF00383.17 AIN96136.1 - 5.7e-13 48.3 3.2 2e-10 40.2 2.2 2.9 1 1 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region FAD_binding_5 PF00941.16 AIN96136.1 - 0.031 13.7 0.1 0.041 13.3 0.1 1.2 1 0 0 1 1 1 0 FAD binding domain in molybdopterin dehydrogenase Bd3614-deam PF14439.1 AIN96136.1 - 0.2 11.5 2.5 0.67 9.8 1.7 2.0 1 1 0 1 1 1 0 Bd3614-like deaminase MTHFR PF02219.12 AIN96139.1 - 0.048 12.7 0.0 15 4.6 0.0 2.9 3 0 0 3 3 3 0 Methylenetetrahydrofolate reductase WD40 PF00400.27 AIN96141.1 - 2.3e-85 277.7 17.1 1.2e-10 40.8 0.1 8.1 8 0 0 8 8 8 8 WD domain, G-beta repeat Nup160 PF11715.3 AIN96141.1 - 2.4e-08 32.5 13.2 0.009 14.1 0.0 6.1 2 1 2 5 5 5 4 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 AIN96141.1 - 0.0086 14.8 0.4 7.4 5.2 0.0 3.0 1 1 2 3 3 3 2 Nup133 N terminal like PBP1_TM PF14812.1 AIN96143.1 - 1.9 8.8 30.5 1.2 9.5 1.8 5.8 6 0 0 6 6 6 0 Transmembrane domain of transglycosylase PBP1 at N-terminal BetaGal_dom3 PF13363.1 AIN96144.1 - 0.035 13.5 0.1 0.1 11.9 0.1 1.8 1 0 0 1 1 1 0 Beta-galactosidase, domain 3 Nucleoplasmin PF03066.10 AIN96144.1 - 1.4 8.4 7.1 2.4 7.6 0.2 2.7 3 0 0 3 3 3 0 Nucleoplasmin TPR_11 PF13414.1 AIN96145.1 - 6.7e-07 28.8 0.9 7.2e-06 25.5 1.1 2.4 2 0 0 2 2 2 1 TPR repeat TPR_2 PF07719.12 AIN96145.1 - 3.7e-05 23.3 1.7 0.21 11.6 0.0 4.0 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.1 AIN96145.1 - 0.0011 18.8 3.7 0.013 15.4 2.3 2.7 1 1 0 1 1 1 1 Tetratricopeptide repeat TPR_1 PF00515.23 AIN96145.1 - 0.0016 17.9 0.5 0.08 12.5 0.0 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.1 AIN96145.1 - 0.0066 17.0 3.9 0.0066 17.0 2.7 1.9 2 0 0 2 2 2 1 Tetratricopeptide repeat Apc3 PF12895.2 AIN96145.1 - 0.019 15.1 0.3 0.058 13.5 0.1 1.8 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 DUF2153 PF09921.4 AIN96145.1 - 0.051 13.1 0.1 0.12 11.9 0.1 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2153) TPR_9 PF13371.1 AIN96145.1 - 0.12 12.2 4.2 1.7 8.5 0.0 2.7 1 1 1 2 2 2 0 Tetratricopeptide repeat Pkinase PF00069.20 AIN96146.1 - 1.7e-21 76.5 0.0 4.3e-17 62.1 0.0 2.4 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 AIN96146.1 - 6.7e-06 25.3 0.0 0.0049 15.9 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase A_deaminase PF00962.17 AIN96147.1 - 1.1e-09 37.7 0.9 0.00046 19.1 0.0 3.3 3 0 0 3 3 3 3 Adenosine/AMP deaminase NTF2 PF02136.15 AIN96148.1 - 3.6e-26 91.8 0.4 4e-26 91.7 0.3 1.0 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain Lumazine_bd_2 PF12893.2 AIN96148.1 - 0.0058 17.1 0.1 0.0059 17.1 0.1 1.4 1 1 0 1 1 1 1 Putative lumazine-binding DUF4440 PF14534.1 AIN96148.1 - 0.0075 16.4 0.0 0.0091 16.1 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) SnoaL_2 PF12680.2 AIN96148.1 - 0.047 14.0 0.1 0.059 13.7 0.0 1.1 1 0 0 1 1 1 0 SnoaL-like domain Nop16 PF09420.5 AIN96149.1 - 1.1e-25 90.6 5.1 3.9e-25 88.8 3.5 1.7 1 1 0 1 1 1 1 Ribosome biogenesis protein Nop16 YpjP PF14005.1 AIN96149.1 - 0.053 13.2 0.1 0.076 12.7 0.1 1.2 1 0 0 1 1 1 0 YpjP-like protein DUF1758 PF05585.7 AIN96149.1 - 0.15 11.6 0.1 0.21 11.1 0.0 1.2 1 0 0 1 1 1 0 Putative peptidase (DUF1758) FKBP_C PF00254.23 AIN96151.1 - 4.5e-25 87.4 0.0 6.1e-25 87.0 0.0 1.2 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase IQ PF00612.22 AIN96152.1 - 0.00019 20.7 54.3 0.3 10.8 1.4 9.6 8 0 0 8 8 8 7 IQ calmodulin-binding motif Ras PF00071.17 AIN96153.1 - 3.5e-58 195.5 0.1 4.1e-58 195.3 0.1 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 AIN96153.1 - 3.5e-18 66.2 0.0 5.5e-18 65.5 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 AIN96153.1 - 3e-14 52.6 0.0 3.8e-14 52.3 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 AIN96153.1 - 6.6e-07 28.9 0.0 1.6e-06 27.7 0.0 1.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 AIN96153.1 - 2.9e-06 27.2 0.0 4.4e-06 26.6 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_15 PF13175.1 AIN96153.1 - 0.0015 17.7 0.0 0.0018 17.3 0.0 1.1 1 0 0 1 1 1 1 AAA ATPase domain Gtr1_RagA PF04670.7 AIN96153.1 - 0.0042 16.2 0.1 0.0058 15.8 0.0 1.3 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.5 AIN96153.1 - 0.0043 16.2 0.2 0.0078 15.4 0.0 1.5 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit AAA_22 PF13401.1 AIN96153.1 - 0.0047 17.0 0.0 0.0077 16.3 0.0 1.5 1 1 0 1 1 1 1 AAA domain DUF258 PF03193.11 AIN96153.1 - 0.006 15.7 0.2 0.016 14.4 0.1 1.8 2 1 0 2 2 2 1 Protein of unknown function, DUF258 ATP_bind_1 PF03029.12 AIN96153.1 - 0.02 14.4 0.1 0.1 12.0 0.0 1.9 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein FeoB_N PF02421.13 AIN96153.1 - 0.02 14.1 0.0 0.049 12.9 0.0 1.6 2 0 0 2 2 2 0 Ferrous iron transport protein B DUF4555 PF15093.1 AIN96153.1 - 0.024 13.5 0.0 0.034 13.0 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4555) Septin PF00735.13 AIN96153.1 - 0.028 13.4 0.1 0.046 12.7 0.1 1.3 1 0 0 1 1 1 0 Septin ABC_tran PF00005.22 AIN96153.1 - 0.06 13.6 0.0 0.077 13.2 0.0 1.4 1 1 0 1 1 1 0 ABC transporter Amidase02_C PF12123.3 AIN96153.1 - 0.081 12.5 0.1 0.21 11.2 0.0 1.7 2 0 0 2 2 2 0 N-acetylmuramoyl-l-alanine amidase AAA_29 PF13555.1 AIN96153.1 - 0.14 11.6 0.0 0.29 10.6 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF2101 PF09874.4 AIN96154.1 - 7.8 5.9 13.1 0.93 8.9 6.2 1.5 2 0 0 2 2 2 0 Predicted membrane protein (DUF2101) IF-2B PF01008.12 AIN96158.1 - 1.4e-42 145.6 0.0 3.9e-40 137.5 0.0 2.1 2 0 0 2 2 2 2 Initiation factor 2 subunit family PNP_UDP_1 PF01048.15 AIN96161.1 - 7.5e-43 146.1 0.5 9.6e-43 145.8 0.4 1.1 1 0 0 1 1 1 1 Phosphorylase superfamily Mito_carr PF00153.22 AIN96162.1 - 1.4e-23 82.3 5.4 8.3e-09 35.0 0.4 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein RRM_6 PF14259.1 AIN96163.1 - 2.3e-08 33.9 0.0 5.4e-08 32.7 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 AIN96163.1 - 5.7e-07 29.0 0.0 1.2e-06 28.0 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 AIN96163.1 - 0.00051 19.8 0.1 0.0018 18.1 0.0 1.9 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) VirB8 PF04335.8 AIN96163.1 - 0.03 13.9 0.0 0.065 12.8 0.0 1.6 1 0 0 1 1 1 0 VirB8 protein BLVR PF06375.6 AIN96163.1 - 4.1 7.2 9.2 0.57 9.9 3.5 1.8 2 0 0 2 2 2 0 Bovine leukaemia virus receptor (BLVR) DUF1042 PF06294.6 AIN96164.1 - 9.6e-15 54.5 0.0 2.6e-14 53.1 0.0 1.7 2 0 0 2 2 2 1 Domain of Unknown Function (DUF1042) CAMSAP_CH PF11971.3 AIN96164.1 - 0.0017 17.9 0.0 0.0036 16.9 0.0 1.4 1 0 0 1 1 1 1 CAMSAP CH domain CH PF00307.26 AIN96164.1 - 0.18 11.8 0.0 0.38 10.8 0.0 1.5 1 0 0 1 1 1 0 Calponin homology (CH) domain DnaJ PF00226.26 AIN96165.1 - 1.8e-07 30.7 0.5 3.1e-07 30.0 0.3 1.4 1 0 0 1 1 1 1 DnaJ domain DUF1491 PF07372.7 AIN96166.1 - 0.0018 18.1 0.3 0.0037 17.1 0.2 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1491) PAGK PF15284.1 AIN96166.1 - 0.088 12.5 0.1 0.22 11.2 0.0 1.6 2 0 0 2 2 2 0 Phage-encoded virulence factor Autoind_synth PF00765.12 AIN96166.1 - 0.17 11.1 0.0 0.27 10.4 0.0 1.3 1 0 0 1 1 1 0 Autoinducer synthetase EMP24_GP25L PF01105.19 AIN96167.1 - 0.36 10.5 7.4 0.41 10.3 0.0 3.2 3 0 0 3 3 3 0 emp24/gp25L/p24 family/GOLD NPV_P10 PF05531.7 AIN96167.1 - 0.5 10.6 0.1 0.5 10.6 0.0 3.7 5 0 0 5 5 5 0 Nucleopolyhedrovirus P10 protein IncA PF04156.9 AIN96167.1 - 3.3 7.2 0.0 3.3 7.2 0.0 4.4 4 1 1 5 5 5 0 IncA protein DUF972 PF06156.8 AIN96167.1 - 4.9 7.5 18.7 18 5.7 4.5 4.5 3 3 2 5 5 5 0 Protein of unknown function (DUF972) MIF4G PF02854.14 AIN96168.1 - 8.7e-15 54.6 2.8 1.6e-14 53.8 0.4 2.3 3 0 0 3 3 3 1 MIF4G domain TetR_C_8 PF14278.1 AIN96168.1 - 0.01 16.2 0.4 12 6.4 0.0 3.5 2 1 0 2 2 2 2 Transcriptional regulator C-terminal region DUF4041 PF13250.1 AIN96168.1 - 0.015 14.8 0.0 0.044 13.3 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4041) Herpes_BLRF2 PF05812.7 AIN96168.1 - 0.045 13.5 0.8 0.1 12.4 0.5 1.5 1 0 0 1 1 1 0 Herpesvirus BLRF2 protein Sporozoite_P67 PF05642.6 AIN96168.1 - 0.74 7.6 3.2 1.2 6.9 2.2 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen COX2_TM PF02790.10 AIN96169.1 - 0.031 14.2 0.5 0.031 14.2 0.3 2.7 1 1 2 3 3 3 0 Cytochrome C oxidase subunit II, transmembrane domain COX15-CtaA PF02628.10 AIN96169.1 - 0.097 11.5 8.4 0.14 10.9 5.8 1.3 1 0 0 1 1 1 0 Cytochrome oxidase assembly protein Pox_P21 PF05313.7 AIN96169.1 - 0.7 9.1 9.6 0.36 10.0 0.3 2.1 2 0 0 2 2 2 0 Poxvirus P21 membrane protein LsmAD PF06741.8 AIN96171.1 - 1.9e-22 79.1 2.3 4.6e-22 77.8 1.6 1.7 1 0 0 1 1 1 1 LsmAD domain SM-ATX PF14438.1 AIN96171.1 - 3.3e-12 46.1 0.0 7.2e-12 45.0 0.0 1.6 1 0 0 1 1 1 1 Ataxin 2 SM domain TPR_2 PF07719.12 AIN96173.1 - 0.017 14.9 0.6 3.1 7.9 0.2 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat zf-C3HC4_3 PF13920.1 AIN96174.1 - 7.2e-16 57.6 11.7 1.6e-15 56.4 8.1 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 AIN96174.1 - 3.6e-08 33.2 14.6 8.5e-08 32.0 10.1 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 AIN96174.1 - 4e-05 23.3 13.4 9.3e-05 22.1 9.3 1.7 1 0 0 1 1 1 1 Ring finger domain Prok-RING_4 PF14447.1 AIN96174.1 - 0.0088 15.5 5.4 0.021 14.3 3.8 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_4 PF14570.1 AIN96174.1 - 0.14 11.7 8.4 0.26 10.8 5.9 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING_5 PF14634.1 AIN96174.1 - 0.22 11.3 12.9 0.55 10.0 9.0 1.7 1 0 0 1 1 1 0 zinc-RING finger domain zf-P11 PF03854.9 AIN96174.1 - 1.1 8.7 11.0 2.6 7.5 7.6 1.5 1 0 0 1 1 1 0 P-11 zinc finger Trichoplein PF13868.1 AIN96175.1 - 6.7e-69 231.9 155.8 6.7e-69 231.9 108.0 2.0 2 0 0 2 2 2 1 Tumour suppressor, Mitostatin LPP PF04728.8 AIN96175.1 - 0.04 13.7 3.0 0.85 9.4 0.2 2.8 2 0 0 2 2 2 0 Lipoprotein leucine-zipper Ras PF00071.17 AIN96176.1 - 9.7e-54 181.1 0.0 1.1e-53 180.8 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 AIN96176.1 - 1.1e-16 61.4 0.0 2.7e-16 60.1 0.0 1.6 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 AIN96176.1 - 1.2e-11 44.2 0.0 1.5e-11 43.8 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 AIN96176.1 - 1.4e-07 31.1 0.0 3.2e-06 26.7 0.0 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 AIN96176.1 - 6.4e-06 26.1 0.0 1.1e-05 25.2 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 AIN96176.1 - 3.1e-05 23.2 0.2 4.8e-05 22.6 0.1 1.5 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_18 PF13238.1 AIN96176.1 - 0.00082 19.6 0.0 0.0016 18.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 AIN96176.1 - 0.0013 18.7 0.1 0.0043 17.0 0.0 1.8 1 1 1 2 2 2 1 AAA ATPase domain PduV-EutP PF10662.4 AIN96176.1 - 0.0022 17.5 0.0 0.02 14.4 0.0 2.0 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation DUF258 PF03193.11 AIN96176.1 - 0.0027 16.9 0.1 0.0093 15.1 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function, DUF258 SRPRB PF09439.5 AIN96176.1 - 0.014 14.6 0.0 0.021 14.0 0.0 1.5 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit ABC_tran PF00005.22 AIN96176.1 - 0.023 14.9 0.0 0.054 13.7 0.0 1.7 1 1 0 1 1 1 0 ABC transporter AAA_17 PF13207.1 AIN96176.1 - 0.025 15.3 0.1 0.037 14.8 0.1 1.7 1 1 0 1 1 1 0 AAA domain ATP_bind_1 PF03029.12 AIN96176.1 - 0.043 13.3 0.3 3.6 7.0 0.0 2.2 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein RNA_helicase PF00910.17 AIN96176.1 - 0.044 13.9 0.0 0.14 12.3 0.0 1.8 2 0 0 2 2 2 0 RNA helicase AAA_22 PF13401.1 AIN96176.1 - 0.046 13.8 0.0 0.14 12.2 0.0 2.1 1 1 0 1 1 1 0 AAA domain AAA_24 PF13479.1 AIN96176.1 - 0.058 12.9 0.0 0.13 11.8 0.0 1.6 2 0 0 2 2 2 0 AAA domain IIGP PF05049.8 AIN96176.1 - 0.087 11.6 0.0 0.15 10.8 0.0 1.4 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) Septin PF00735.13 AIN96176.1 - 0.11 11.5 0.0 0.2 10.6 0.0 1.4 1 0 0 1 1 1 0 Septin Ras PF00071.17 AIN96177.1 - 3e-46 156.7 0.0 3.5e-46 156.5 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 AIN96177.1 - 5.5e-13 49.4 0.0 8.3e-13 48.8 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 AIN96177.1 - 5.3e-07 29.0 0.0 6e-07 28.8 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 AIN96177.1 - 4.3e-06 26.0 0.0 5.1e-06 25.7 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 AIN96177.1 - 9.4e-05 21.9 0.0 0.0055 16.1 0.0 2.1 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 AIN96177.1 - 0.029 14.3 0.0 0.056 13.3 0.0 1.5 1 1 0 1 1 1 0 50S ribosome-binding GTPase Gemini_mov PF01708.11 AIN96178.1 - 0.19 11.2 2.1 9.1 5.9 0.0 2.2 2 0 0 2 2 2 0 Geminivirus putative movement protein DUF3099 PF11298.3 AIN96178.1 - 0.3 10.8 5.7 8.2 6.2 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3099) RIB43A PF05914.7 AIN96179.1 - 1.1e-112 376.3 60.9 1.4e-112 376.1 42.2 1.0 1 0 0 1 1 1 1 RIB43A zf-RanBP PF00641.13 AIN96180.1 - 2.6e-07 29.6 23.3 0.00088 18.3 1.3 3.4 3 0 0 3 3 3 3 Zn-finger in Ran binding protein and others DZR PF12773.2 AIN96180.1 - 4e-06 26.5 18.0 0.0013 18.4 7.5 2.3 1 1 1 2 2 2 2 Double zinc ribbon zf-RING_3 PF14369.1 AIN96180.1 - 0.084 12.8 0.7 0.084 12.8 0.5 3.3 3 1 0 3 3 3 0 zinc-finger zf-ribbon_3 PF13248.1 AIN96180.1 - 3 7.1 20.8 0.22 10.7 2.0 3.5 3 0 0 3 3 3 0 zinc-ribbon domain DUF3279 PF11682.3 AIN96180.1 - 5 6.7 18.5 1.4 8.5 0.7 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF3279) Atx10homo_assoc PF09759.4 AIN96183.1 - 1.7e-30 104.7 0.0 2.8e-30 104.0 0.0 1.4 1 0 0 1 1 1 1 Spinocerebellar ataxia type 10 protein domain zf-CHY PF05495.7 AIN96185.1 - 0.051 13.7 0.2 0.1 12.7 0.1 1.4 1 0 0 1 1 1 0 CHY zinc finger Methyltransf_23 PF13489.1 AIN96186.1 - 2.5e-27 95.5 0.1 3.6e-27 95.0 0.1 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 AIN96186.1 - 2e-06 28.1 0.1 6.2e-05 23.4 0.0 2.3 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 AIN96186.1 - 5.6e-06 26.7 0.0 8.7e-05 22.9 0.0 2.3 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 AIN96186.1 - 0.00023 20.7 0.0 0.00055 19.5 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 AIN96186.1 - 0.031 14.8 0.1 3.7 8.1 0.0 2.9 2 1 1 3 3 3 0 Methyltransferase domain Ubie_methyltran PF01209.13 AIN96186.1 - 0.11 11.6 0.0 0.19 10.7 0.0 1.4 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family DUF1861 PF08950.5 AIN96187.1 - 1.3e-137 457.5 0.2 1.5e-137 457.3 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1861) DUF1861 PF08950.5 AIN96188.1 - 5.2e-136 452.3 0.2 5.9e-136 452.1 0.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1861) DUF1861 PF08950.5 AIN96189.1 - 8.2e-141 468.0 0.3 9.5e-141 467.8 0.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1861) TylF PF05711.6 AIN96189.1 - 0.066 12.2 0.0 0.11 11.5 0.0 1.3 1 0 0 1 1 1 0 Macrocin-O-methyltransferase (TylF) DUF1861 PF08950.5 AIN96190.1 - 9.4e-141 467.8 0.0 1.1e-140 467.6 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1861) DUF1861 PF08950.5 AIN96191.1 - 3.3e-136 452.9 0.3 3.8e-136 452.7 0.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1861) DUF1861 PF08950.5 AIN96192.1 - 5.4e-142 471.9 0.0 6.2e-142 471.7 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1861) PHO4 PF01384.15 AIN96193.1 - 1.4e-108 362.4 16.7 2.1e-108 361.8 11.6 1.3 1 0 0 1 1 1 1 Phosphate transporter family BT1 PF03092.11 AIN96194.1 - 6.8e-148 492.9 12.1 8.4e-148 492.6 8.4 1.0 1 0 0 1 1 1 1 BT1 family FA_desaturase PF00487.19 AIN96195.1 - 4.8e-28 98.3 24.7 4.8e-28 98.3 17.1 1.7 1 1 1 2 2 2 1 Fatty acid desaturase DUF3474 PF11960.3 AIN96195.1 - 0.012 15.6 0.0 0.025 14.6 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3474) DUF4131 PF13567.1 AIN96195.1 - 0.45 9.9 4.2 0.28 10.5 0.4 2.2 2 1 0 2 2 2 0 Domain of unknown function (DUF4131) DUF3150 PF11348.3 AIN96196.1 - 0.023 13.8 0.9 0.032 13.3 0.2 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3150) DUF1342 PF07072.6 AIN96196.1 - 0.079 12.6 4.1 0.11 12.1 2.3 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1342) DUF4200 PF13863.1 AIN96196.1 - 0.14 12.1 11.8 0.15 12.0 7.5 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4200) KLRAQ PF10205.4 AIN96196.1 - 0.3 11.1 8.0 0.19 11.7 3.2 2.2 1 1 1 2 2 2 0 Predicted coiled-coil domain-containing protein Microtub_bind PF13931.1 AIN96196.1 - 0.54 10.3 5.4 0.21 11.7 1.6 1.7 1 1 1 2 2 2 0 Kinesin-associated microtubule-binding V_ATPase_I PF01496.14 AIN96196.1 - 0.87 7.3 5.2 1 7.1 3.6 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DivIC PF04977.10 AIN96196.1 - 0.9 9.0 5.2 4.4 6.8 3.6 2.2 1 1 0 1 1 1 0 Septum formation initiator TMF_TATA_bd PF12325.3 AIN96196.1 - 1 9.0 11.0 0.74 9.5 4.8 2.5 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding CENP-H PF05837.7 AIN96196.1 - 1.6 8.9 8.4 1 9.5 3.0 2.2 1 1 1 2 2 2 0 Centromere protein H (CENP-H) ATG16 PF08614.6 AIN96196.1 - 1.8 8.3 12.1 2.7 7.7 8.3 1.5 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) COPIIcoated_ERV PF07970.7 AIN96197.1 - 6.6e-52 176.3 0.1 3.3e-51 174.0 0.1 1.8 2 0 0 2 2 2 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.1 AIN96197.1 - 2e-05 24.4 0.0 4.9e-05 23.2 0.0 1.7 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) NMDAR2_C PF10565.4 AIN96197.1 - 0.069 11.8 0.3 0.094 11.3 0.2 1.1 1 0 0 1 1 1 0 N-methyl D-aspartate receptor 2B3 C-terminus Hexapep PF00132.19 AIN96198.1 - 1.2e-13 49.9 3.7 0.0002 20.7 0.0 3.3 3 0 0 3 3 3 3 Bacterial transferase hexapeptide (six repeats) DUF3891 PF13030.1 AIN96198.1 - 0.069 12.6 0.1 0.1 12.0 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3891) Hexapep_2 PF14602.1 AIN96198.1 - 0.12 12.0 4.5 16 5.1 0.0 3.3 2 1 1 3 3 3 0 Hexapeptide repeat of succinyl-transferase ABC_tran PF00005.22 AIN96199.1 - 2.7e-27 95.7 0.0 5.2e-27 94.8 0.0 1.5 2 0 0 2 2 2 1 ABC transporter AAA_21 PF13304.1 AIN96199.1 - 1.4e-07 31.8 1.5 2.7e-05 24.3 1.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_10 PF12846.2 AIN96199.1 - 0.00033 20.1 0.5 0.24 10.8 0.2 2.3 2 0 0 2 2 2 2 AAA-like domain SMC_N PF02463.14 AIN96199.1 - 0.00076 18.7 0.1 0.006 15.8 0.0 2.0 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 AIN96199.1 - 0.0039 17.1 0.2 0.013 15.5 0.0 1.9 2 0 0 2 2 2 1 AAA ATPase domain DUF258 PF03193.11 AIN96199.1 - 0.0079 15.3 0.0 0.013 14.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_29 PF13555.1 AIN96199.1 - 0.02 14.4 0.2 0.04 13.4 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain SbcCD_C PF13558.1 AIN96199.1 - 0.02 14.7 3.8 0.023 14.6 0.1 2.7 3 1 0 3 3 2 0 Putative exonuclease SbcCD, C subunit AAA_25 PF13481.1 AIN96199.1 - 0.029 13.7 0.2 0.17 11.2 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.1 AIN96199.1 - 0.037 14.1 2.4 0.85 9.7 0.1 2.5 2 1 1 3 3 3 0 AAA domain AAA_17 PF13207.1 AIN96199.1 - 0.077 13.8 0.4 0.38 11.5 0.0 2.3 2 1 0 2 2 2 0 AAA domain DUF1341 PF07071.6 AIN96199.1 - 0.13 11.8 0.0 0.19 11.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1341) SNF2_N PF00176.18 AIN96200.1 - 6.9e-26 90.7 0.0 1.3e-25 89.8 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain HNH PF01844.18 AIN96200.1 - 1.8e-08 34.0 0.2 1.8e-08 34.0 0.1 2.7 2 0 0 2 2 2 1 HNH endonuclease Helicase_C PF00271.26 AIN96200.1 - 0.00011 21.9 0.0 0.00023 20.9 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Tenui_NS3 PF05310.7 AIN96200.1 - 0.029 14.2 0.1 0.067 13.0 0.0 1.6 1 0 0 1 1 1 0 Tenuivirus movement protein Pkinase PF00069.20 AIN96201.1 - 3.5e-42 144.3 0.0 9.9e-29 100.2 0.0 2.4 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 AIN96201.1 - 1.2e-17 63.8 0.0 1.2e-10 40.9 0.0 2.4 2 0 0 2 2 2 2 Protein tyrosine kinase RWD PF05773.17 AIN96201.1 - 5.6e-07 29.4 0.0 1.2e-06 28.3 0.0 1.6 1 0 0 1 1 1 1 RWD domain APH PF01636.18 AIN96201.1 - 0.0091 15.7 0.0 0.028 14.1 0.0 1.8 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.9 AIN96201.1 - 0.079 12.0 0.0 0.2 10.6 0.0 1.6 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family NCD1 PF04904.8 AIN96201.1 - 0.098 12.4 0.0 0.3 10.8 0.0 1.8 1 0 0 1 1 1 0 NAB conserved region 1 (NCD1) Metal_resist PF13801.1 AIN96202.1 - 0.08 12.9 11.0 0.11 12.5 0.3 3.2 2 1 1 3 3 3 0 Heavy-metal resistance Filament PF00038.16 AIN96202.1 - 0.12 11.7 43.1 0.27 10.6 7.7 3.4 1 1 1 3 3 3 0 Intermediate filament protein IncA PF04156.9 AIN96202.1 - 0.15 11.6 49.6 1.5 8.3 3.6 3.3 1 1 2 3 3 3 0 IncA protein Mnd1 PF03962.10 AIN96202.1 - 0.23 11.0 40.2 2.1 7.9 10.3 3.3 2 1 1 3 3 3 0 Mnd1 family ERM PF00769.14 AIN96202.1 - 0.46 9.9 49.5 0.72 9.3 18.1 2.8 1 1 2 3 3 3 0 Ezrin/radixin/moesin family GAS PF13851.1 AIN96202.1 - 2.2 7.4 41.1 8.3 5.5 2.1 3.3 2 1 0 2 2 2 0 Growth-arrest specific micro-tubule binding Dynamitin PF04912.9 AIN96202.1 - 2.4 6.8 38.6 0.12 11.1 11.6 3.1 1 1 1 3 3 3 0 Dynamitin AAA_13 PF13166.1 AIN96202.1 - 2.7 6.3 35.5 0.1 11.0 11.1 2.1 1 1 1 2 2 2 0 AAA domain Atg14 PF10186.4 AIN96202.1 - 3.6 6.4 40.3 0.025 13.5 16.0 2.8 1 1 2 3 3 3 0 UV radiation resistance protein and autophagy-related subunit 14 DUF1204 PF06721.6 AIN96202.1 - 4.9 6.3 19.1 0.15 11.2 1.7 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1204) Med9 PF07544.8 AIN96202.1 - 5.8 6.7 26.7 0.079 12.7 0.9 5.0 3 2 2 5 5 5 0 RNA polymerase II transcription mediator complex subunit 9 Baculo_PEP_C PF04513.7 AIN96202.1 - 5.9 6.7 30.9 0.035 13.9 4.3 3.8 1 1 3 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus Pox_A_type_inc PF04508.7 AIN96202.1 - 10 6.2 10.6 6.3 6.8 0.0 5.4 6 0 0 6 6 6 0 Viral A-type inclusion protein repeat GRIP PF01465.15 AIN96203.1 - 4.1e-14 51.8 0.0 8.2e-14 50.8 0.0 1.6 1 0 0 1 1 1 1 GRIP domain Fzo_mitofusin PF04799.8 AIN96203.1 - 0.013 14.9 2.7 0.033 13.5 1.6 1.7 1 1 0 1 1 1 0 fzo-like conserved region Phage_GP20 PF06810.6 AIN96203.1 - 0.081 12.3 6.6 0.99 8.8 1.7 2.4 2 0 0 2 2 2 0 Phage minor structural protein GP20 HAUS-augmin3 PF14932.1 AIN96203.1 - 0.11 11.6 9.6 0.022 13.9 3.2 2.0 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 3 Muted PF14942.1 AIN96203.1 - 0.15 11.8 5.9 0.13 12.1 2.2 2.2 2 0 0 2 2 2 0 Organelle biogenesis, Muted-like protein DUF972 PF06156.8 AIN96203.1 - 0.27 11.5 9.6 2.2 8.6 0.1 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF972) APG6 PF04111.7 AIN96203.1 - 0.56 9.1 11.4 0.19 10.7 4.4 2.0 2 0 0 2 2 2 0 Autophagy protein Apg6 FlaC_arch PF05377.6 AIN96203.1 - 1.6 8.6 7.6 0.28 11.0 0.3 3.0 4 0 0 4 4 3 0 Flagella accessory protein C (FlaC) bZIP_1 PF00170.16 AIN96203.1 - 1.6 8.7 16.7 5.3 7.0 4.0 4.0 2 1 1 3 3 3 0 bZIP transcription factor Atg14 PF10186.4 AIN96203.1 - 2.2 7.1 11.3 0.12 11.3 3.9 1.6 2 0 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 Fmp27_WPPW PF10359.4 AIN96203.1 - 3.1 6.1 9.5 1 7.6 3.9 2.0 1 1 1 2 2 2 0 RNA pol II promoter Fmp27 protein domain IncA PF04156.9 AIN96203.1 - 3.4 7.2 19.4 3.7 7.1 10.7 2.4 2 1 1 3 3 3 0 IncA protein TMF_TATA_bd PF12325.3 AIN96203.1 - 3.9 7.2 14.9 0.87 9.3 6.5 2.3 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding Adeno_PIX PF03955.9 AIN96203.1 - 5 7.6 7.3 2.9 8.4 1.5 2.6 2 1 0 2 2 2 0 Adenovirus hexon-associated protein (IX) DUF1192 PF06698.6 AIN96203.1 - 5.5 6.8 12.9 12 5.7 3.5 3.5 3 1 0 3 3 3 0 Protein of unknown function (DUF1192) Seryl_tRNA_N PF02403.17 AIN96203.1 - 8.3 6.4 13.8 2 8.4 5.1 2.5 3 0 0 3 3 2 0 Seryl-tRNA synthetase N-terminal domain TMF_DNA_bd PF12329.3 AIN96203.1 - 9.1 6.1 14.9 18 5.2 0.2 2.9 3 0 0 3 3 2 0 TATA element modulatory factor 1 DNA binding RRM_1 PF00076.17 AIN96204.1 - 5.4e-05 22.7 0.0 0.00012 21.6 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) MORN PF02493.15 AIN96205.1 - 8e-25 85.0 31.8 1.2e-06 27.8 0.3 6.6 7 0 0 7 7 7 6 MORN repeat tRNA-synt_2b PF00587.20 AIN96206.1 - 4.4e-32 111.0 0.0 7.3e-32 110.3 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.17 AIN96206.1 - 3.1e-14 52.9 3.1 1.4e-13 50.7 0.3 2.2 1 1 1 2 2 2 1 Seryl-tRNA synthetase N-terminal domain DUF2540 PF10802.3 AIN96206.1 - 0.038 13.6 0.1 0.098 12.3 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2540) Pkinase PF00069.20 AIN96207.1 - 3.5e-48 164.0 0.0 4.3e-48 163.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AIN96207.1 - 1.3e-25 89.9 0.0 1.9e-25 89.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 AIN96207.1 - 1.2e-10 40.8 0.0 2.8e-10 39.6 0.0 1.4 1 1 0 1 1 1 1 Kinase-like APH PF01636.18 AIN96207.1 - 0.00014 21.6 0.6 0.00074 19.3 0.1 2.0 1 1 0 2 2 2 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 AIN96207.1 - 0.0013 17.6 0.1 0.002 17.0 0.1 1.1 1 0 0 1 1 1 1 Seadornavirus VP7 Kdo PF06293.9 AIN96207.1 - 0.0036 16.4 0.1 0.0069 15.4 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.15 AIN96207.1 - 0.038 13.5 0.0 0.059 12.9 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase RIO1 PF01163.17 AIN96207.1 - 0.15 11.4 0.0 0.27 10.5 0.0 1.3 1 0 0 1 1 1 0 RIO1 family NIF3 PF01784.13 AIN96209.1 - 7.9e-63 212.2 0.0 9.2e-63 212.0 0.0 1.0 1 0 0 1 1 1 1 NIF3 (NGG1p interacting factor 3) PSP1 PF04468.7 AIN96210.1 - 1.3e-30 105.2 0.1 2.5e-30 104.2 0.1 1.4 1 0 0 1 1 1 1 PSP1 C-terminal conserved region Macoilin PF09726.4 AIN96211.1 - 0.032 12.5 28.9 0.072 11.3 20.0 1.4 1 0 0 1 1 1 0 Transmembrane protein Peptidase_S64 PF08192.6 AIN96211.1 - 4.8 5.3 20.9 7.3 4.7 14.5 1.1 1 0 0 1 1 1 0 Peptidase family S64 3-PAP PF12578.3 AIN96213.1 - 1.8e-33 115.3 2.6 1.8e-33 115.3 1.8 3.1 4 1 1 5 5 5 1 Myotubularin-associated protein Dzip-like_N PF13815.1 AIN96213.1 - 0.00018 21.2 2.3 0.00018 21.2 1.6 3.3 2 1 1 3 3 3 1 Iguana/Dzip1-like DAZ-interacting protein N-terminal PUA PF01472.15 AIN96214.1 - 1.3e-12 47.1 1.5 2.4e-12 46.4 1.1 1.4 1 0 0 1 1 1 1 PUA domain DUF4160 PF13711.1 AIN96214.1 - 0.0032 17.2 0.1 0.0053 16.5 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4160) FumaraseC_C PF10415.4 AIN96214.1 - 0.094 12.7 0.1 0.17 11.9 0.1 1.3 1 0 0 1 1 1 0 Fumarase C C-terminus DEAD PF00270.24 AIN96215.1 - 3.3e-22 78.7 0.0 5.3e-22 78.1 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 AIN96215.1 - 3.2e-07 30.1 0.0 7.9e-07 28.8 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 AIN96215.1 - 5.3e-05 23.1 0.0 0.00011 22.1 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit PhoH PF02562.11 AIN96215.1 - 0.072 12.3 0.0 0.13 11.5 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein Pyrophosphatase PF00719.14 AIN96217.1 - 7.8e-49 165.0 0.2 1.5e-48 164.1 0.0 1.5 2 0 0 2 2 2 1 Inorganic pyrophosphatase EF-hand_7 PF13499.1 AIN96217.1 - 0.061 13.4 0.0 0.061 13.4 0.0 2.0 2 0 0 2 2 2 0 EF-hand domain pair EF-hand_9 PF14658.1 AIN96217.1 - 0.099 12.5 0.0 0.23 11.3 0.0 1.6 1 0 0 1 1 1 0 EF-hand domain Pterin_4a PF01329.14 AIN96218.1 - 1.4e-29 101.7 0.0 1.5e-29 101.5 0.0 1.0 1 0 0 1 1 1 1 Pterin 4 alpha carbinolamine dehydratase Rad51 PF08423.6 AIN96219.1 - 3.1e-15 55.7 0.0 5.9e-15 54.8 0.0 1.4 1 0 0 1 1 1 1 Rad51 AAA_25 PF13481.1 AIN96219.1 - 2.1e-11 43.5 0.1 5.2e-11 42.3 0.1 1.6 1 0 0 1 1 1 1 AAA domain KaiC PF06745.8 AIN96219.1 - 6.4e-07 28.7 0.0 7.9e-06 25.1 0.0 2.0 2 0 0 2 2 2 1 KaiC DnaB_C PF03796.10 AIN96219.1 - 2.5e-05 23.3 0.0 0.081 11.8 0.0 2.1 2 0 0 2 2 2 2 DnaB-like helicase C terminal domain AAA PF00004.24 AIN96219.1 - 0.00018 21.7 0.1 0.00092 19.4 0.0 1.9 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.1 AIN96219.1 - 0.00097 18.8 0.1 0.0043 16.7 0.1 2.1 1 0 0 1 1 1 1 Part of AAA domain AAA_22 PF13401.1 AIN96219.1 - 0.002 18.2 0.0 0.0042 17.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain RecA PF00154.16 AIN96219.1 - 0.0029 16.7 0.0 0.0077 15.3 0.0 1.6 2 0 0 2 2 2 1 recA bacterial DNA recombination protein AAA_33 PF13671.1 AIN96219.1 - 0.017 15.0 0.0 0.038 13.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.10 AIN96219.1 - 0.024 14.3 0.0 0.039 13.6 0.0 1.4 1 0 0 1 1 1 0 NTPase AAA_17 PF13207.1 AIN96219.1 - 0.058 14.2 0.4 0.14 13.0 0.3 1.8 1 1 0 1 1 1 0 AAA domain Proteasome PF00227.21 AIN96220.1 - 7.4e-57 191.7 0.1 1e-56 191.2 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 AIN96220.1 - 8.5e-15 53.7 0.2 1.4e-14 53.0 0.1 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature EF-hand_like PF09279.6 AIN96220.1 - 0.008 16.1 1.0 0.46 10.5 0.7 2.5 2 0 0 2 2 2 1 Phosphoinositide-specific phospholipase C, efhand-like DUF365 PF04033.7 AIN96220.1 - 0.052 13.5 0.3 0.11 12.5 0.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF365) Pkinase PF00069.20 AIN96221.1 - 6.4e-45 153.3 0.0 2.4e-38 131.8 0.0 2.9 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 AIN96221.1 - 3e-27 95.3 0.0 8.4e-21 74.1 0.0 3.2 3 0 0 3 3 3 3 Protein tyrosine kinase Kinase-like PF14531.1 AIN96221.1 - 0.0002 20.4 0.0 0.037 12.9 0.0 2.2 2 0 0 2 2 2 2 Kinase-like YrbL-PhoP_reg PF10707.4 AIN96221.1 - 0.088 12.1 0.0 0.21 10.9 0.0 1.5 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL HJURP_C PF12347.3 AIN96221.1 - 0.26 10.9 2.7 0.87 9.2 0.0 2.9 3 0 0 3 3 3 0 Holliday junction regulator protein family C-terminal repeat PEPCK_ATP PF01293.15 AIN96222.1 - 0.09 11.2 0.0 0.13 10.7 0.0 1.1 1 0 0 1 1 1 0 Phosphoenolpyruvate carboxykinase FAD_binding_6 PF00970.19 AIN96223.1 - 4e-08 33.3 0.0 1.1e-07 31.9 0.0 1.7 2 0 0 2 2 2 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.16 AIN96223.1 - 0.15 12.6 0.0 0.35 11.4 0.0 1.6 1 0 0 1 1 1 0 Oxidoreductase NAD-binding domain Sec20 PF03908.8 AIN96226.1 - 2.4e-10 39.9 4.0 4.4e-10 39.1 2.3 1.7 2 0 0 2 2 2 1 Sec20 TMEM247 PF15444.1 AIN96226.1 - 0.32 10.7 4.3 0.17 11.6 0.2 2.3 1 1 0 2 2 2 0 Transmembrane protein 247 TFIIF_alpha PF05793.7 AIN96226.1 - 0.5 8.6 2.4 0.59 8.4 1.6 1.0 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Ctr PF04145.10 AIN96226.1 - 0.58 10.2 7.1 2.7 8.0 4.5 2.3 1 1 1 2 2 2 0 Ctr copper transporter family Vps5 PF09325.5 AIN96226.1 - 4.3 6.5 7.8 0.88 8.7 2.5 1.8 2 0 0 2 2 2 0 Vps5 C terminal like APC_CDC26 PF10471.4 AIN96226.1 - 9.3 7.0 7.7 0.77 10.5 1.3 2.3 3 1 1 4 4 4 0 Anaphase-promoting complex APC subunit 1 PIF1 PF05970.9 AIN96228.1 - 2.5e-30 105.6 2.2 3e-23 82.3 0.7 3.7 3 1 0 3 3 3 3 PIF1-like helicase AAA_30 PF13604.1 AIN96228.1 - 1.6e-15 57.2 0.3 4e-15 55.9 0.2 1.8 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 AIN96228.1 - 0.00017 21.7 0.7 0.0015 18.6 0.4 2.7 2 1 0 2 2 2 1 AAA domain Herpes_Helicase PF02689.9 AIN96228.1 - 0.00022 19.1 1.4 0.21 9.3 0.0 2.6 3 0 0 3 3 3 2 Helicase AAA_11 PF13086.1 AIN96228.1 - 0.0011 18.5 1.4 0.39 10.2 0.0 3.5 2 1 1 3 3 3 1 AAA domain DUF853 PF05872.7 AIN96228.1 - 0.0015 16.9 1.2 0.003 15.9 0.8 1.4 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF853) UvrD_C_2 PF13538.1 AIN96228.1 - 0.021 14.9 0.0 0.081 13.0 0.0 2.1 1 1 0 1 1 1 0 UvrD-like helicase C-terminal domain ATP-synt_ab PF00006.20 AIN96228.1 - 0.064 12.7 0.1 1.8 8.0 0.0 2.4 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain Viral_helicase1 PF01443.13 AIN96228.1 - 0.12 11.8 0.9 8.2 5.8 0.0 3.0 2 1 0 2 2 2 0 Viral (Superfamily 1) RNA helicase AAA_19 PF13245.1 AIN96228.1 - 0.15 11.7 5.1 0.037 13.7 0.4 2.4 2 0 0 2 2 2 0 Part of AAA domain PIF1 PF05970.9 AIN96229.1 - 3.5e-35 121.6 0.8 6.6e-28 97.6 0.1 3.4 2 1 1 3 3 3 3 PIF1-like helicase AAA_30 PF13604.1 AIN96229.1 - 5.5e-15 55.4 0.1 6.4e-14 51.9 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 AIN96229.1 - 0.00023 21.3 0.0 0.0011 19.0 0.0 2.2 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 AIN96229.1 - 0.00085 19.0 6.8 0.0019 17.9 2.9 3.1 2 0 0 2 2 2 1 Part of AAA domain AAA_11 PF13086.1 AIN96229.1 - 0.005 16.4 0.0 1.2 8.6 0.0 2.8 1 1 0 2 2 2 1 AAA domain Mg_chelatase PF01078.16 AIN96229.1 - 0.0058 15.8 0.1 0.014 14.5 0.1 1.6 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_16 PF13191.1 AIN96229.1 - 0.0063 16.5 2.2 0.011 15.7 0.1 2.5 2 0 0 2 2 2 1 AAA ATPase domain Herpes_Helicase PF02689.9 AIN96229.1 - 0.0085 13.8 0.3 0.036 11.8 0.0 1.9 2 0 0 2 2 2 1 Helicase AAA PF00004.24 AIN96229.1 - 0.0087 16.2 0.0 0.027 14.6 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) PhoH PF02562.11 AIN96229.1 - 0.014 14.6 0.1 0.057 12.6 0.0 2.0 2 0 0 2 2 2 0 PhoH-like protein AAA_5 PF07728.9 AIN96229.1 - 0.018 14.7 0.0 0.062 13.0 0.0 1.9 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) UvrD_C_2 PF13538.1 AIN96229.1 - 0.036 14.2 0.0 0.14 12.3 0.0 2.1 1 1 0 1 1 1 0 UvrD-like helicase C-terminal domain NACHT PF05729.7 AIN96229.1 - 0.13 11.9 0.1 0.26 10.9 0.0 1.5 1 0 0 1 1 1 0 NACHT domain NTPase_1 PF03266.10 AIN96229.1 - 0.23 11.1 1.2 0.53 9.9 0.2 2.0 2 0 0 2 2 2 0 NTPase MobB PF03205.9 AIN96229.1 - 0.33 10.6 2.3 0.32 10.6 0.3 1.9 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B 14-3-3 PF00244.15 AIN96231.1 - 1.4e-92 309.0 0.9 1.6e-92 308.8 0.6 1.0 1 0 0 1 1 1 1 14-3-3 protein OPA3 PF07047.7 AIN96232.1 - 4.1e-16 58.9 0.1 1.9e-08 34.1 0.0 2.4 2 0 0 2 2 2 2 Optic atrophy 3 protein (OPA3) DUF2779 PF11074.3 AIN96234.1 - 2.1e-41 141.0 0.0 3.4e-41 140.3 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function(DUF2779) DUF3450 PF11932.3 AIN96234.1 - 0.23 10.6 4.9 0.53 9.5 3.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) Usp PF00582.21 AIN96235.1 - 0.02 15.0 0.2 0.25 11.5 0.0 2.6 2 0 0 2 2 2 0 Universal stress protein family TTL PF03133.10 AIN96236.1 - 6.5e-67 225.5 0.0 1.1e-66 224.7 0.0 1.3 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.1 AIN96236.1 - 5.2e-07 28.7 0.1 0.00071 18.4 0.0 3.2 2 1 1 3 3 3 2 YheC/D like ATP-grasp ATP-grasp_3 PF02655.9 AIN96236.1 - 0.018 14.9 0.0 0.05 13.4 0.0 1.7 2 0 0 2 2 2 0 ATP-grasp domain BOP1NT PF08145.7 AIN96237.1 - 5e-88 295.2 7.6 7.7e-88 294.5 5.3 1.3 1 0 0 1 1 1 1 BOP1NT (NUC169) domain WD40 PF00400.27 AIN96237.1 - 1.6e-26 91.1 1.0 9.9e-11 41.1 0.0 5.6 5 0 0 5 5 5 3 WD domain, G-beta repeat Apc4_WD40 PF12894.2 AIN96237.1 - 0.083 12.4 0.0 25 4.4 0.0 3.3 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain RCC1 PF00415.13 AIN96238.1 - 2.1e-24 85.4 16.1 7.7e-07 29.2 0.0 8.3 7 2 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 AIN96238.1 - 5.5e-11 41.7 22.2 8.5e-06 25.2 0.5 6.2 5 0 0 5 5 5 3 Regulator of chromosome condensation (RCC1) repeat LRR_4 PF12799.2 AIN96240.1 - 9e-15 53.9 11.4 1.2e-05 24.7 0.2 4.1 3 1 0 3 3 3 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 AIN96240.1 - 1.5e-09 37.4 16.0 0.0029 17.3 1.6 3.5 2 1 1 3 3 3 3 Leucine rich repeat LRR_1 PF00560.28 AIN96240.1 - 1.4e-07 30.5 16.7 0.9 9.8 0.1 6.4 6 0 0 6 6 6 4 Leucine Rich Repeat LRR_6 PF13516.1 AIN96240.1 - 0.0011 18.7 14.1 0.55 10.4 0.2 5.6 5 1 1 6 6 6 2 Leucine Rich repeat LRR_7 PF13504.1 AIN96240.1 - 0.0057 16.6 23.3 0.78 10.2 0.1 6.5 7 0 0 7 7 7 1 Leucine rich repeat TMF_TATA_bd PF12325.3 AIN96240.1 - 0.14 11.8 0.3 0.31 10.7 0.2 1.5 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding LRR_9 PF14580.1 AIN96240.1 - 0.19 11.3 2.1 5.2 6.5 0.4 2.1 1 1 1 2 2 2 0 Leucine-rich repeat DNA_ligase_A_M PF01068.16 AIN96241.1 - 0.00024 20.5 0.0 1.1 8.5 0.0 3.4 4 0 0 4 4 4 2 ATP dependent DNA ligase domain DNA_ligase_OB_2 PF14743.1 AIN96241.1 - 0.025 14.2 0.0 0.091 12.4 0.0 2.0 2 0 0 2 2 2 0 DNA ligase OB-like domain RIIa PF02197.12 AIN96242.1 - 0.16 11.4 0.5 1.4 8.3 0.1 2.2 2 0 0 2 2 2 0 Regulatory subunit of type II PKA R-subunit PUF PF00806.14 AIN96243.1 - 2.2e-10 39.4 0.0 0.035 13.5 0.0 5.9 5 0 0 5 5 5 3 Pumilio-family RNA binding repeat CPL PF08144.6 AIN96243.1 - 0.12 12.1 2.3 0.66 9.7 0.1 3.4 2 2 2 4 4 4 0 CPL (NUC119) domain Pox_MCEL PF03291.11 AIN96245.1 - 1.2e-14 53.9 0.0 1.9e-14 53.2 0.0 1.2 1 0 0 1 1 1 1 mRNA capping enzyme Methyltransf_25 PF13649.1 AIN96245.1 - 2e-06 28.0 0.0 8.2e-06 26.1 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 AIN96245.1 - 9.2e-06 25.4 0.0 2.1e-05 24.3 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 AIN96245.1 - 2.5e-05 24.8 0.0 9.1e-05 23.0 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 AIN96245.1 - 4.3e-05 23.9 0.0 0.00015 22.1 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 AIN96245.1 - 4.7e-05 23.7 0.0 0.00014 22.2 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain NSP13 PF06460.7 AIN96245.1 - 0.042 12.7 0.0 0.072 11.9 0.0 1.2 1 0 0 1 1 1 0 Coronavirus NSP13 Methyltransf_31 PF13847.1 AIN96245.1 - 0.052 13.1 0.0 0.096 12.2 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain FmrO PF07091.6 AIN96245.1 - 0.26 10.2 0.0 0.52 9.2 0.0 1.4 1 0 0 1 1 1 0 Ribosomal RNA methyltransferase (FmrO) PHF5 PF03660.9 AIN96245.1 - 0.3 11.1 5.3 0.07 13.1 0.9 2.0 2 0 0 2 2 2 0 PHF5-like protein TPR_11 PF13414.1 AIN96246.1 - 2.6e-28 97.4 8.7 1.2e-09 37.7 0.0 5.0 2 1 4 6 6 6 5 TPR repeat TPR_1 PF00515.23 AIN96246.1 - 4.4e-18 64.0 7.5 0.00018 20.9 0.2 6.2 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_2 PF07719.12 AIN96246.1 - 1.2e-17 62.2 5.8 0.00021 20.9 0.4 6.9 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_16 PF13432.1 AIN96246.1 - 1.2e-12 48.1 1.1 0.00041 20.9 0.0 4.9 3 3 2 5 5 5 3 Tetratricopeptide repeat TPR_8 PF13181.1 AIN96246.1 - 4.9e-12 44.7 3.1 0.0024 17.5 0.5 5.8 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_17 PF13431.1 AIN96246.1 - 3.6e-10 39.2 7.0 0.025 14.7 0.0 5.8 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_12 PF13424.1 AIN96246.1 - 3.8e-10 39.5 4.3 0.0021 17.9 0.4 4.5 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.1 AIN96246.1 - 3.2e-07 30.5 2.9 0.58 10.5 0.1 4.4 4 2 0 4 4 4 3 Tetratricopeptide repeat TPR_7 PF13176.1 AIN96246.1 - 3.5e-06 26.3 0.0 0.044 13.6 0.0 4.1 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.1 AIN96246.1 - 6e-06 26.4 1.9 0.11 13.1 0.0 4.6 3 2 3 6 6 4 2 Tetratricopeptide repeat TPR_6 PF13174.1 AIN96246.1 - 0.00029 21.0 10.4 0.25 11.8 0.0 5.3 6 0 0 6 6 4 2 Tetratricopeptide repeat DUF3808 PF10300.4 AIN96246.1 - 0.00044 18.9 0.3 0.002 16.7 0.1 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF3808) TPR_10 PF13374.1 AIN96246.1 - 0.0085 15.9 3.3 0.41 10.6 0.0 4.0 3 1 1 4 4 4 1 Tetratricopeptide repeat MIT PF04212.13 AIN96246.1 - 0.033 14.0 13.4 1.3 8.9 0.1 4.7 6 0 0 6 6 5 0 MIT (microtubule interacting and transport) domain Sel1 PF08238.7 AIN96246.1 - 0.035 14.7 2.5 0.34 11.6 0.2 3.1 3 0 0 3 3 3 0 Sel1 repeat HYLS1_C PF15311.1 AIN96246.1 - 0.067 13.4 0.0 0.18 12.0 0.0 1.7 1 0 0 1 1 1 0 Hydrolethalus syndrome protein 1 C-terminus TPR_9 PF13371.1 AIN96246.1 - 0.24 11.2 6.0 2.7 7.8 0.0 4.5 4 2 1 5 5 5 0 Tetratricopeptide repeat Pkinase PF00069.20 AIN96249.1 - 3.7e-34 118.0 0.0 6e-34 117.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AIN96249.1 - 4.1e-14 52.2 0.0 2.4e-12 46.4 0.0 2.3 2 0 0 2 2 2 1 Protein tyrosine kinase RIO1 PF01163.17 AIN96249.1 - 0.00067 19.0 0.2 0.0015 17.8 0.0 1.6 2 0 0 2 2 2 1 RIO1 family Pox_ser-thr_kin PF05445.6 AIN96249.1 - 0.0007 18.4 0.1 0.0011 17.8 0.0 1.2 1 0 0 1 1 1 1 Poxvirus serine/threonine protein kinase APH PF01636.18 AIN96249.1 - 0.04 13.6 0.0 0.089 12.5 0.0 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kinase-like PF14531.1 AIN96249.1 - 0.05 12.5 0.5 0.11 11.4 0.1 1.7 2 1 0 2 2 2 0 Kinase-like Choline_kinase PF01633.15 AIN96249.1 - 0.098 12.2 0.1 0.22 11.0 0.0 1.5 1 0 0 1 1 1 0 Choline/ethanolamine kinase AA_permease_2 PF13520.1 AIN96250.1 - 1.3e-18 66.7 37.7 1.3e-18 66.7 26.2 1.3 1 1 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 AIN96250.1 - 6.6e-07 28.0 35.6 1.5e-06 26.8 24.7 1.5 1 1 0 1 1 1 1 Amino acid permease DUF563 PF04577.9 AIN96252.1 - 2e-13 50.7 0.8 4.4e-13 49.6 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF563) Nucleoside_tran PF01733.13 AIN96253.1 - 4e-34 118.1 11.7 4.5e-25 88.4 0.0 2.7 2 1 1 3 3 3 2 Nucleoside transporter Tex_N PF09371.5 AIN96254.1 - 7.1e-44 149.4 0.0 1.5e-43 148.4 0.0 1.6 1 0 0 1 1 1 1 Tex-like protein N-terminal domain HHH_3 PF12836.2 AIN96254.1 - 7.4e-10 38.6 0.0 1.6e-09 37.5 0.0 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix motif YqgF PF14639.1 AIN96254.1 - 9e-07 28.5 0.0 2.3e-06 27.2 0.0 1.7 1 0 0 1 1 1 1 Holliday-junction resolvase-like of SPT6 HHH_7 PF14635.1 AIN96254.1 - 0.0059 16.7 0.0 0.013 15.6 0.0 1.5 1 0 0 1 1 1 1 Helix-hairpin-helix motif S1 PF00575.18 AIN96254.1 - 0.018 15.1 0.0 0.054 13.5 0.0 1.8 2 0 0 2 2 2 0 S1 RNA binding domain PAZ PF02170.17 AIN96255.1 - 3.8e-09 35.9 0.0 9.8e-09 34.6 0.0 1.6 1 0 0 1 1 1 1 PAZ domain Piwi PF02171.12 AIN96255.1 - 1.6e-06 27.3 0.1 1.4e-05 24.1 0.0 2.2 2 0 0 2 2 2 1 Piwi domain Cyt-b5 PF00173.23 AIN96256.1 - 1.6e-18 66.2 0.0 2.6e-18 65.5 0.0 1.3 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain DUF1653 PF07866.6 AIN96256.1 - 0.11 12.7 0.4 2.5 8.3 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1653) SPW PF03779.9 AIN96256.1 - 0.18 11.1 0.8 0.3 10.4 0.3 1.6 2 0 0 2 2 2 0 SPW repeat Carboxyl_trans PF01039.17 AIN96257.1 - 9.8e-148 492.5 0.0 1.3e-147 492.0 0.0 1.1 1 0 0 1 1 1 1 Carboxyl transferase domain MdcE PF06833.6 AIN96257.1 - 2.5e-06 26.8 0.0 0.013 14.6 0.0 2.3 2 0 0 2 2 2 2 Malonate decarboxylase gamma subunit (MdcE) zf-C4H2 PF10146.4 AIN96258.1 - 0.013 15.5 0.0 0.022 14.8 0.0 1.3 1 0 0 1 1 1 0 Zinc finger-containing protein ESX-1_EspG PF14011.1 AIN96260.1 - 0.065 12.4 5.8 0.43 9.7 3.8 1.8 1 1 1 2 2 2 0 EspG family Peptidase_M17 PF00883.16 AIN96261.1 - 3.7e-84 282.2 0.4 5e-84 281.8 0.3 1.2 1 0 0 1 1 1 1 Cytosol aminopeptidase family, catalytic domain DUF3132 PF11330.3 AIN96261.1 - 0.0058 16.4 0.0 0.011 15.5 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3132) MFS_1 PF07690.11 AIN96263.1 - 1e-21 77.0 36.7 1.7e-18 66.4 14.7 2.2 2 0 0 2 2 2 2 Major Facilitator Superfamily Nodulin-like PF06813.8 AIN96263.1 - 1.8e-09 37.2 11.3 1e-08 34.7 7.8 2.3 1 1 0 1 1 1 1 Nodulin-like MFS_1 PF07690.11 AIN96264.1 - 1e-11 44.1 13.4 1e-11 44.1 9.3 2.5 3 0 0 3 3 3 2 Major Facilitator Superfamily Nodulin-like PF06813.8 AIN96264.1 - 3.7e-07 29.6 13.7 3.7e-07 29.6 9.5 3.1 2 1 0 2 2 2 1 Nodulin-like PMP1_2 PF08114.6 AIN96264.1 - 0.028 13.8 0.4 7.3 6.1 0.1 3.5 2 0 0 2 2 2 0 ATPase proteolipid family MFS_1 PF07690.11 AIN96265.1 - 1.4e-12 47.0 43.4 1.1e-09 37.5 16.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Nodulin-like PF06813.8 AIN96265.1 - 2e-08 33.8 24.3 5e-08 32.4 12.6 3.1 2 2 2 4 4 4 2 Nodulin-like Ank_2 PF12796.2 AIN96266.1 - 9e-32 109.2 0.4 2.7e-11 43.6 0.1 3.1 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 AIN96266.1 - 4.2e-25 86.2 1.1 5.7e-07 29.0 0.1 5.3 5 0 0 5 5 5 4 Ankyrin repeat Ank_4 PF13637.1 AIN96266.1 - 4.3e-22 78.0 1.8 2.4e-07 31.0 0.0 4.5 2 2 3 5 5 5 5 Ankyrin repeats (many copies) Ank_5 PF13857.1 AIN96266.1 - 5.2e-21 74.1 2.6 1e-05 25.5 0.8 4.1 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 AIN96266.1 - 1.8e-17 61.6 0.5 0.0013 18.7 0.0 4.8 5 0 0 5 5 5 3 Ankyrin repeat ArsA_ATPase PF02374.10 AIN96267.1 - 3.2e-88 295.6 0.0 1.8e-50 171.7 0.0 2.3 2 1 0 2 2 2 2 Anion-transporting ATPase CbiA PF01656.18 AIN96267.1 - 4.2e-11 42.6 1.7 6.7e-10 38.7 1.0 2.6 2 1 0 2 2 2 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_25 PF13481.1 AIN96267.1 - 0.00073 18.9 0.0 0.0022 17.4 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_31 PF13614.1 AIN96267.1 - 0.0038 17.1 0.0 0.023 14.6 0.0 2.1 2 0 0 2 2 2 1 AAA domain SRP54 PF00448.17 AIN96267.1 - 0.0065 15.9 0.2 1.7 8.0 0.2 2.4 2 0 0 2 2 2 2 SRP54-type protein, GTPase domain NB-ARC PF00931.17 AIN96267.1 - 0.014 14.3 0.1 0.029 13.2 0.1 1.4 1 0 0 1 1 1 0 NB-ARC domain Fer4_NifH PF00142.13 AIN96267.1 - 0.016 14.3 0.0 0.53 9.4 0.0 2.3 2 0 0 2 2 2 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family AAA_19 PF13245.1 AIN96267.1 - 0.039 13.7 0.0 0.16 11.7 0.0 2.1 1 0 0 1 1 1 0 Part of AAA domain VEK-30 PF12107.3 AIN96268.1 - 0.0053 16.3 2.7 0.098 12.3 1.8 2.9 2 0 0 2 2 2 1 Plasminogen (Pg) ligand in fibrinolytic pathway DUF948 PF06103.6 AIN96268.1 - 2.8 7.8 9.0 0.63 9.9 0.1 3.6 3 2 2 5 5 5 0 Bacterial protein of unknown function (DUF948) Peptidase_C11 PF03415.9 AIN96269.1 - 9.5e-06 24.8 0.0 1.4e-05 24.2 0.0 1.2 1 0 0 1 1 1 1 Clostripain family Glyco_hydro_7 PF00840.15 AIN96270.1 - 0.31 9.3 0.1 0.49 8.6 0.1 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 7 DUF4471 PF14740.1 AIN96271.1 - 0.14 11.3 0.0 0.22 10.7 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4471) MIT PF04212.13 AIN96272.1 - 0.11 12.3 0.9 0.19 11.6 0.6 1.4 1 0 0 1 1 1 0 MIT (microtubule interacting and transport) domain Ribosomal_S21e PF01249.13 AIN96273.1 - 1.5e-32 111.3 0.1 1.9e-32 111.0 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein S21e Tox-GHH2 PF15635.1 AIN96273.1 - 0.085 13.2 0.4 0.13 12.6 0.3 1.3 1 0 0 1 1 1 0 GHH signature containing HNH/Endo VII superfamily nuclease toxin 2 Ribosomal_S21e PF01249.13 AIN96274.1 - 1.9e-32 111.0 0.1 2.5e-32 110.6 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein S21e Tox-GHH2 PF15635.1 AIN96274.1 - 0.11 12.8 0.5 0.18 12.1 0.4 1.3 1 0 0 1 1 1 0 GHH signature containing HNH/Endo VII superfamily nuclease toxin 2 COX6B PF02297.12 AIN96275.1 - 9.9e-05 22.2 10.0 0.014 15.3 1.2 2.8 1 1 1 2 2 2 2 Cytochrome oxidase c subunit VIb UPF0203 PF05254.7 AIN96275.1 - 0.01 15.6 8.6 5.8 6.8 0.2 3.6 2 1 1 3 3 3 0 Uncharacterised protein family (UPF0203) EF-hand_6 PF13405.1 AIN96277.1 - 1.8e-12 45.9 0.1 0.73 9.8 0.0 6.9 7 0 0 7 7 7 4 EF-hand domain EF-hand_7 PF13499.1 AIN96277.1 - 1.8e-09 37.5 0.0 1.4 9.1 0.0 5.6 5 0 0 5 5 5 3 EF-hand domain pair EF-hand_1 PF00036.27 AIN96277.1 - 0.00075 18.6 0.0 7.7 6.0 0.0 4.9 6 0 0 6 6 6 1 EF hand EF-hand_8 PF13833.1 AIN96277.1 - 0.098 12.2 0.0 66 3.2 0.0 4.1 4 0 0 4 4 4 0 EF-hand domain pair DUF3552 PF12072.3 AIN96278.1 - 4.7e-05 22.6 11.3 7e-05 22.1 7.9 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3552) Atg14 PF10186.4 AIN96278.1 - 0.014 14.3 6.1 0.021 13.8 4.2 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 APG6 PF04111.7 AIN96278.1 - 0.81 8.6 11.3 1.1 8.2 7.8 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 V_ATPase_I PF01496.14 AIN96278.1 - 1.8 6.3 5.7 2.3 5.9 3.9 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF1993 PF09351.5 AIN96278.1 - 3.1 7.7 9.3 0.13 12.1 1.6 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF1993) TMF_DNA_bd PF12329.3 AIN96279.1 - 0.004 16.9 14.4 0.004 16.9 10.0 2.7 1 1 1 2 2 2 1 TATA element modulatory factor 1 DNA binding LRS4 PF10422.4 AIN96279.1 - 0.023 14.0 9.4 0.061 12.6 6.5 1.7 1 0 0 1 1 1 0 Monopolin complex subunit LRS4 DUF342 PF03961.8 AIN96279.1 - 0.34 9.2 7.3 0.52 8.6 5.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) AAA_13 PF13166.1 AIN96279.1 - 0.85 7.9 8.4 1.2 7.4 5.8 1.1 1 0 0 1 1 1 0 AAA domain Prominin PF05478.6 AIN96279.1 - 1.5 6.2 1.8 2.4 5.5 1.3 1.2 1 0 0 1 1 1 0 Prominin DUF2317 PF10079.4 AIN96279.1 - 2.1 6.8 11.5 3.5 6.1 8.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2317) Spc7 PF08317.6 AIN96279.1 - 3.5 6.1 13.0 6.4 5.3 9.0 1.4 1 0 0 1 1 1 0 Spc7 kinetochore protein IncA PF04156.9 AIN96279.1 - 5.3 6.5 21.1 0.37 10.3 10.9 1.8 2 0 0 2 2 2 0 IncA protein APG6 PF04111.7 AIN96279.1 - 6.3 5.7 13.3 11 4.9 9.2 1.4 1 0 0 1 1 1 0 Autophagy protein Apg6 Abhydrolase_6 PF12697.2 AIN96280.1 - 5.1e-13 49.4 1.0 1e-12 48.4 0.7 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 AIN96280.1 - 2.7e-05 23.9 0.0 4.3e-05 23.3 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 AIN96280.1 - 0.043 13.3 0.1 0.34 10.4 0.0 2.4 1 1 1 2 2 2 0 alpha/beta hydrolase fold HEAT PF02985.17 AIN96281.1 - 0.06 13.4 11.2 9.9 6.5 0.0 6.6 7 0 0 7 7 7 0 HEAT repeat Kinesin PF00225.18 AIN96282.1 - 1.7e-87 293.3 0.0 2.9e-86 289.2 0.0 2.3 1 1 0 1 1 1 1 Kinesin motor domain START PF01852.14 AIN96283.1 - 4e-18 65.4 0.0 7.8e-18 64.5 0.0 1.4 1 0 0 1 1 1 1 START domain LRR_6 PF13516.1 AIN96284.1 - 1.1e-23 80.5 11.6 0.024 14.6 0.0 12.1 12 0 0 12 12 12 5 Leucine Rich repeat LRR_4 PF12799.2 AIN96284.1 - 1.4e-13 50.1 14.1 0.0039 16.7 0.2 9.3 9 2 2 11 11 11 5 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 AIN96284.1 - 4.1e-11 41.2 16.5 1.6 9.0 0.2 11.8 13 0 0 13 13 13 4 Leucine Rich Repeat LRR_8 PF13855.1 AIN96284.1 - 6.1e-08 32.3 19.6 0.063 13.0 1.6 7.5 8 0 0 8 8 8 4 Leucine rich repeat LRR_7 PF13504.1 AIN96284.1 - 0.00019 21.1 24.6 26 5.5 0.0 11.0 12 0 0 12 12 12 1 Leucine rich repeat Ribosomal_L24e PF01246.15 AIN96285.1 - 2.5e-30 104.1 2.0 2.5e-30 104.1 1.4 2.5 3 0 0 3 3 3 1 Ribosomal protein L24e zf-FCS PF06467.9 AIN96285.1 - 0.054 13.1 7.0 0.094 12.3 4.8 1.4 1 0 0 1 1 1 0 MYM-type Zinc finger with FCS sequence motif TraT PF05818.7 AIN96285.1 - 4.7 6.5 6.4 3.6 6.9 3.6 1.5 1 1 0 1 1 1 0 Enterobacterial TraT complement resistance protein AAA PF00004.24 AIN96286.1 - 2.1e-39 134.7 0.0 7.6e-39 132.9 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 AIN96286.1 - 1.3e-06 28.5 0.0 3.4e-06 27.2 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_2 PF07724.9 AIN96286.1 - 0.00014 21.8 0.0 0.00032 20.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.1 AIN96286.1 - 0.00021 21.3 4.3 0.0013 18.7 0.6 3.6 2 1 0 2 2 2 1 AAA ATPase domain AAA_5 PF07728.9 AIN96286.1 - 0.0024 17.5 0.1 0.028 14.1 0.1 2.6 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_33 PF13671.1 AIN96286.1 - 0.0065 16.3 0.1 0.025 14.4 0.0 2.1 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.12 AIN96286.1 - 0.0088 15.4 0.0 0.018 14.4 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_17 PF13207.1 AIN96286.1 - 0.038 14.8 1.9 0.072 13.9 0.1 2.4 2 0 0 2 2 2 0 AAA domain Mg_chelatase PF01078.16 AIN96286.1 - 0.039 13.1 0.1 0.087 11.9 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_18 PF13238.1 AIN96286.1 - 0.041 14.1 0.0 0.11 12.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain PUB PF09409.5 AIN96287.1 - 2.4e-13 49.6 0.0 4.9e-13 48.6 0.0 1.5 1 0 0 1 1 1 1 PUB domain SHOCT PF09851.4 AIN96287.1 - 0.00045 19.5 1.8 0.00065 19.0 0.1 2.2 2 0 0 2 2 2 1 Short C-terminal domain Pol_alpha_B_N PF08418.5 AIN96287.1 - 0.14 11.6 8.9 0.18 11.3 1.7 2.9 3 0 0 3 3 3 0 DNA polymerase alpha subunit B N-terminal DUF4239 PF14023.1 AIN96287.1 - 0.32 10.3 3.6 1.9 7.7 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4239) DUF2052 PF09747.4 AIN96287.1 - 0.87 9.4 9.4 0.17 11.7 3.4 1.9 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) DUF1675 PF07897.6 AIN96287.1 - 1.7 8.4 10.3 0.71 9.6 3.7 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1675) Ctr PF04145.10 AIN96287.1 - 2.2 8.3 5.0 2.9 7.9 2.2 2.2 2 0 0 2 2 2 0 Ctr copper transporter family DUF2992 PF11208.3 AIN96287.1 - 3.6 7.4 13.4 2.8 7.8 7.9 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2992) Surp PF01805.15 AIN96288.1 - 0.0051 16.4 0.1 0.011 15.3 0.1 1.6 1 0 0 1 1 1 1 Surp module SPT6_acidic PF14632.1 AIN96290.1 - 0.0037 17.3 14.8 0.029 14.5 0.0 2.5 2 0 0 2 2 2 1 Acidic N-terminal SPT6 MSP1_C PF07462.6 AIN96290.1 - 0.42 8.9 1.5 4.5 5.5 1.6 2.0 2 0 0 2 2 2 0 Merozoite surface protein 1 (MSP1) C-terminus Ribosomal_S7 PF00177.16 AIN96291.1 - 3e-38 130.6 0.3 3.6e-38 130.4 0.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e Ribosomal_S7 PF00177.16 AIN96292.1 - 3e-38 130.6 0.3 3.6e-38 130.4 0.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e zf-HIT PF04438.11 AIN96293.1 - 5.4e-08 32.3 6.5 1.1e-07 31.3 4.5 1.5 1 0 0 1 1 1 1 HIT zinc finger zf-MYND PF01753.13 AIN96293.1 - 0.011 15.5 4.1 0.025 14.4 2.8 1.6 1 0 0 1 1 1 0 MYND finger Adaptin_N PF01602.15 AIN96294.1 - 2.6e-85 286.7 0.0 3.6e-85 286.2 0.0 1.1 1 0 0 1 1 1 1 Adaptin N terminal region HEAT_2 PF13646.1 AIN96294.1 - 8.5e-08 32.3 6.1 0.014 15.6 0.1 5.1 3 2 1 4 4 4 3 HEAT repeats Cnd1 PF12717.2 AIN96294.1 - 0.00028 20.8 0.1 0.0047 16.7 0.0 2.5 2 1 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.1 AIN96294.1 - 0.0049 17.3 8.7 1.9 9.0 0.0 5.9 6 1 1 7 7 7 1 HEAT-like repeat Pacs-1 PF10254.4 AIN96294.1 - 0.21 10.1 0.1 0.49 8.9 0.1 1.5 1 0 0 1 1 1 0 PACS-1 cytosolic sorting protein PEP-utilizers_C PF02896.13 AIN96295.1 - 7.4e-100 333.6 0.0 1.3e-99 332.8 0.0 1.4 1 0 0 1 1 1 1 PEP-utilising enzyme, TIM barrel domain PPDK_N PF01326.14 AIN96295.1 - 8.6e-61 205.7 0.2 1.7e-60 204.8 0.0 1.5 2 0 0 2 2 2 1 Pyruvate phosphate dikinase, PEP/pyruvate binding domain PEP-utilizers PF00391.18 AIN96295.1 - 2.9e-22 78.0 0.3 7.6e-22 76.6 0.2 1.7 1 0 0 1 1 1 1 PEP-utilising enzyme, mobile domain Sigma70_r4 PF04545.11 AIN96295.1 - 0.015 14.5 0.0 0.043 13.1 0.0 1.8 1 0 0 1 1 1 0 Sigma-70, region 4 HTH_24 PF13412.1 AIN96295.1 - 0.018 14.3 0.0 0.044 13.1 0.0 1.6 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding DUF3788 PF12663.2 AIN96295.1 - 0.053 13.1 0.0 0.14 11.7 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3788) HTH_AsnC-type PF13404.1 AIN96295.1 - 0.11 11.9 0.1 0.29 10.7 0.1 1.7 1 0 0 1 1 1 0 AsnC-type helix-turn-helix domain Exo_endo_phos PF03372.18 AIN96296.1 - 3.6e-08 33.6 0.0 4e-07 30.2 0.0 2.1 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family SecY PF00344.15 AIN96300.1 - 3.9e-85 285.8 10.3 4.8e-85 285.5 7.1 1.1 1 0 0 1 1 1 1 SecY translocase Plug_translocon PF10559.4 AIN96300.1 - 3.4e-15 55.2 0.1 7.1e-15 54.2 0.0 1.6 1 0 0 1 1 1 1 Plug domain of Sec61p TMEM237 PF15383.1 AIN96300.1 - 0.0046 16.1 0.2 0.0083 15.2 0.1 1.3 1 0 0 1 1 1 1 Transmembrane protein 237 zf-DHHC PF01529.15 AIN96301.1 - 7e-25 87.4 14.7 7e-25 87.4 10.2 1.9 1 1 1 2 2 2 1 DHHC palmitoyltransferase zf-DHHC PF01529.15 AIN96302.1 - 1.1e-21 76.9 20.2 1.1e-21 76.9 14.0 2.1 1 1 1 2 2 2 1 DHHC palmitoyltransferase p450 PF00067.17 AIN96303.1 - 2.7e-66 223.9 0.0 3.2e-66 223.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Ribosomal_L28e PF01778.12 AIN96305.1 - 1.1e-11 45.1 0.2 1.9e-11 44.3 0.1 1.4 1 0 0 1 1 1 1 Ribosomal L28e protein family WD40 PF00400.27 AIN96306.1 - 1.2e-16 59.8 12.6 5.6e-05 22.8 0.0 6.8 6 0 0 6 6 6 5 WD domain, G-beta repeat Sec16_C PF12931.2 AIN96306.1 - 1.6e-06 28.0 0.0 5e-06 26.4 0.0 1.8 1 1 0 1 1 1 1 Sec23-binding domain of Sec16 TPR_11 PF13414.1 AIN96306.1 - 0.0084 15.7 0.4 0.82 9.3 0.0 2.6 2 0 0 2 2 2 1 TPR repeat TPR_2 PF07719.12 AIN96306.1 - 0.012 15.4 5.8 0.46 10.5 0.6 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.23 AIN96306.1 - 0.013 15.0 1.1 0.44 10.2 0.7 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.1 AIN96306.1 - 0.079 12.9 0.7 6.4 6.7 0.1 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_8 PF13181.1 AIN96306.1 - 0.32 10.8 0.3 1.2 9.0 0.2 1.9 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.1 AIN96306.1 - 2.4 8.1 5.0 2.3 8.2 0.3 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat GTP_EFTU PF00009.22 AIN96307.1 - 4.8e-43 146.7 0.0 9.1e-43 145.8 0.0 1.5 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 AIN96307.1 - 1.3e-21 76.6 0.0 3.3e-21 75.2 0.0 1.7 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain MMR_HSR1 PF01926.18 AIN96307.1 - 0.00018 21.4 0.0 0.0004 20.3 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D2 PF03144.20 AIN96307.1 - 0.00038 20.4 0.5 0.0037 17.3 0.2 2.7 3 0 0 3 3 3 1 Elongation factor Tu domain 2 G-alpha PF00503.15 AIN96307.1 - 0.00065 18.4 1.3 0.00065 18.4 0.9 1.6 2 0 0 2 2 2 1 G-protein alpha subunit Hamartin PF04388.7 AIN96307.1 - 2 6.9 6.4 2.7 6.5 4.4 1.1 1 0 0 1 1 1 0 Hamartin protein TFIIA PF03153.8 AIN96307.1 - 2.7 7.7 19.0 5 6.9 13.2 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit 60KD_IMP PF02096.15 AIN96308.1 - 3.4e-26 92.1 0.1 4.4e-26 91.7 0.1 1.1 1 0 0 1 1 1 1 60Kd inner membrane protein Ribosomal_S8 PF00410.14 AIN96309.1 - 2e-23 82.6 0.0 2.9e-23 82.1 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S8 Solute_trans_a PF03619.11 AIN96310.1 - 5.6e-85 284.9 14.0 7e-85 284.6 9.7 1.1 1 0 0 1 1 1 1 Organic solute transporter Ostalpha Prok-RING_2 PF14445.1 AIN96310.1 - 0.038 13.9 0.4 0.12 12.3 0.3 1.9 1 0 0 1 1 1 0 Prokaryotic RING finger family 2 Skp1 PF01466.14 AIN96311.1 - 1.1e-33 115.0 1.8 1.7e-33 114.5 1.3 1.3 1 0 0 1 1 1 1 Skp1 family, dimerisation domain Skp1_POZ PF03931.10 AIN96311.1 - 2e-12 47.0 0.0 6.3e-12 45.4 0.0 1.8 2 0 0 2 2 2 1 Skp1 family, tetramerisation domain BTB PF00651.26 AIN96311.1 - 0.037 14.0 0.0 0.41 10.6 0.0 2.2 2 0 0 2 2 2 0 BTB/POZ domain ABC_tran PF00005.22 AIN96312.1 - 1.2e-54 184.2 0.0 3.1e-26 92.3 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC2_membrane_3 PF12698.2 AIN96312.1 - 2.2e-53 181.4 59.5 3e-34 118.5 18.6 3.8 3 1 0 3 3 3 2 ABC-2 family transporter protein AAA_21 PF13304.1 AIN96312.1 - 2.8e-16 60.3 0.0 4.5e-06 26.8 0.0 4.4 4 0 0 4 4 4 2 AAA domain AAA_23 PF13476.1 AIN96312.1 - 0.00017 21.9 8.4 0.15 12.3 0.0 3.2 3 0 0 3 3 3 2 AAA domain SRP54 PF00448.17 AIN96312.1 - 0.00023 20.6 0.2 0.52 9.7 0.0 2.3 2 0 0 2 2 2 2 SRP54-type protein, GTPase domain AAA_29 PF13555.1 AIN96312.1 - 0.00037 19.9 0.5 0.41 10.2 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain SbcCD_C PF13558.1 AIN96312.1 - 0.00082 19.2 0.0 0.71 9.8 0.0 3.3 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_15 PF13175.1 AIN96312.1 - 0.002 17.2 0.0 4.4 6.2 0.0 3.9 4 0 0 4 4 4 1 AAA ATPase domain DUF258 PF03193.11 AIN96312.1 - 0.0023 17.1 0.0 0.21 10.7 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function, DUF258 SMC_N PF02463.14 AIN96312.1 - 0.0091 15.2 0.0 16 4.6 0.0 3.4 3 1 0 3 3 3 0 RecF/RecN/SMC N terminal domain Zeta_toxin PF06414.7 AIN96312.1 - 0.0098 15.0 0.2 14 4.7 0.0 3.2 3 0 0 3 3 3 0 Zeta toxin AAA_30 PF13604.1 AIN96312.1 - 0.036 13.6 0.1 0.87 9.1 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_10 PF12846.2 AIN96312.1 - 0.085 12.2 0.2 4.2 6.7 0.1 2.7 3 0 0 3 3 3 0 AAA-like domain AAA PF00004.24 AIN96312.1 - 0.1 12.8 0.2 3.7 7.7 0.0 2.9 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.1 AIN96312.1 - 0.1 11.9 0.0 11 5.3 0.0 2.5 2 0 0 2 2 2 0 AAA domain UPF0079 PF02367.12 AIN96312.1 - 0.1 12.2 1.0 8.6 6.0 0.0 2.8 3 0 0 3 3 3 0 Uncharacterised P-loop hydrolase UPF0079 ABC2_membrane PF01061.19 AIN96312.1 - 0.11 11.6 57.5 0.044 12.9 10.0 5.1 4 1 0 4 4 4 0 ABC-2 type transporter MMR_HSR1 PF01926.18 AIN96312.1 - 0.18 11.7 0.0 72 3.3 0.0 3.5 3 0 0 3 3 3 0 50S ribosome-binding GTPase MobB PF03205.9 AIN96312.1 - 0.25 11.0 0.3 5.7 6.6 0.0 2.4 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B DUF3812 PF12757.2 AIN96312.1 - 0.71 9.8 4.3 1.4 8.9 3.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3812) ABC2_membrane_3 PF12698.2 AIN96315.1 - 2.9e-60 204.1 60.5 4.8e-41 140.9 12.1 2.8 3 1 0 3 3 3 2 ABC-2 family transporter protein ABC_tran PF00005.22 AIN96315.1 - 2.1e-51 173.7 0.0 9.8e-26 90.6 0.0 2.5 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 AIN96315.1 - 1.9e-18 67.4 0.0 8.7e-08 32.4 0.0 4.2 2 2 0 2 2 2 2 AAA domain SMC_N PF02463.14 AIN96315.1 - 1.2e-05 24.6 0.1 0.7 9.0 0.0 3.4 3 0 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_15 PF13175.1 AIN96315.1 - 1.6e-05 24.1 0.0 0.26 10.2 0.0 3.7 4 0 0 4 4 4 2 AAA ATPase domain AAA_23 PF13476.1 AIN96315.1 - 3e-05 24.4 0.5 0.13 12.5 0.0 2.4 2 0 0 2 2 2 2 AAA domain SbcCD_C PF13558.1 AIN96315.1 - 9.8e-05 22.2 0.0 0.057 13.3 0.0 3.5 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_29 PF13555.1 AIN96315.1 - 0.00024 20.5 0.9 0.31 10.6 0.0 2.9 3 0 0 3 3 2 2 P-loop containing region of AAA domain DUF258 PF03193.11 AIN96315.1 - 0.00073 18.7 0.1 0.041 13.0 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 SRP54 PF00448.17 AIN96315.1 - 0.0011 18.4 0.3 0.24 10.8 0.0 2.3 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain ABC2_membrane PF01061.19 AIN96315.1 - 0.0019 17.4 12.2 0.0019 17.4 8.5 4.2 4 1 0 4 4 4 2 ABC-2 type transporter Zeta_toxin PF06414.7 AIN96315.1 - 0.0065 15.5 0.0 2.7 7.0 0.0 3.1 3 0 0 3 3 3 1 Zeta toxin UPF0079 PF02367.12 AIN96315.1 - 0.032 13.8 0.1 5.9 6.5 0.0 2.7 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 AAA_28 PF13521.1 AIN96315.1 - 0.037 14.0 0.1 9.6 6.1 0.1 3.4 3 0 0 3 3 3 0 AAA domain AAA_25 PF13481.1 AIN96315.1 - 0.04 13.3 0.0 6.3 6.1 0.0 2.5 2 0 0 2 2 2 0 AAA domain Arf PF00025.16 AIN96315.1 - 0.062 12.5 0.1 3.8 6.7 0.0 2.5 2 0 0 2 2 2 0 ADP-ribosylation factor family Miro PF08477.8 AIN96315.1 - 0.07 13.6 0.0 22 5.5 0.0 2.9 2 0 0 2 2 2 0 Miro-like protein AAA PF00004.24 AIN96315.1 - 0.07 13.3 0.1 2.3 8.4 0.0 3.1 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.1 AIN96315.1 - 0.093 12.5 0.1 17 5.3 0.0 2.5 2 0 0 2 2 2 0 AAA domain cobW PF02492.14 AIN96315.1 - 0.095 12.1 0.6 3.8 6.9 0.0 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_30 PF13604.1 AIN96315.1 - 0.12 11.9 0.1 2.5 7.6 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.1 AIN96315.1 - 0.17 12.7 0.0 4.7 8.0 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_13 PF13166.1 AIN96315.1 - 0.17 10.3 0.1 4.2 5.7 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.1 AIN96315.1 - 0.18 11.9 0.0 8.3 6.5 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.1 AIN96315.1 - 0.23 11.4 0.0 3.1 7.7 0.0 2.4 2 0 0 2 2 2 0 AAA ATPase domain TatD_DNase PF01026.16 AIN96316.1 - 7e-43 146.6 0.0 9.7e-43 146.2 0.0 1.2 1 0 0 1 1 1 1 TatD related DNase Amidohydro_2 PF04909.9 AIN96316.1 - 0.0018 17.9 0.0 0.14 11.6 0.0 2.3 2 0 0 2 2 2 2 Amidohydrolase ABC2_membrane_3 PF12698.2 AIN96317.1 - 6.1e-61 206.3 52.8 9e-41 140.0 12.7 2.4 2 1 0 2 2 2 2 ABC-2 family transporter protein ABC_tran PF00005.22 AIN96317.1 - 3.7e-50 169.7 0.0 6.1e-25 88.1 0.0 2.6 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 AIN96317.1 - 5e-18 66.0 0.0 1.5e-08 34.9 0.0 4.2 3 1 0 3 3 3 2 AAA domain SMC_N PF02463.14 AIN96317.1 - 1.4e-08 34.2 0.0 0.059 12.5 0.0 3.6 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain SbcCD_C PF13558.1 AIN96317.1 - 3.7e-06 26.7 0.0 0.035 14.0 0.0 3.9 3 2 0 3 3 3 2 Putative exonuclease SbcCD, C subunit AAA_15 PF13175.1 AIN96317.1 - 5.8e-05 22.3 0.0 0.077 12.0 0.0 3.8 4 0 0 4 4 4 1 AAA ATPase domain AAA_23 PF13476.1 AIN96317.1 - 8e-05 23.0 0.2 0.36 11.1 0.0 2.4 2 0 0 2 2 2 2 AAA domain DUF258 PF03193.11 AIN96317.1 - 0.00018 20.7 0.1 0.03 13.4 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 SRP54 PF00448.17 AIN96317.1 - 0.00032 20.2 0.2 0.24 10.7 0.0 2.4 2 0 0 2 2 2 2 SRP54-type protein, GTPase domain AAA_29 PF13555.1 AIN96317.1 - 0.00044 19.7 0.1 0.39 10.2 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_30 PF13604.1 AIN96317.1 - 0.0072 15.9 0.0 0.21 11.1 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_10 PF12846.2 AIN96317.1 - 0.018 14.5 0.2 5.9 6.2 0.1 3.2 3 0 0 3 3 3 0 AAA-like domain Zeta_toxin PF06414.7 AIN96317.1 - 0.023 13.8 0.0 2.6 7.0 0.0 2.6 2 0 0 2 2 2 0 Zeta toxin AAA PF00004.24 AIN96317.1 - 0.042 14.0 0.1 1.6 8.8 0.0 3.1 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.1 AIN96317.1 - 0.054 13.3 0.1 9.7 6.0 0.0 2.6 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.17 AIN96317.1 - 0.067 13.3 0.1 21 5.3 0.0 2.9 2 0 0 2 2 2 0 RNA helicase Arf PF00025.16 AIN96317.1 - 0.068 12.4 0.1 3.3 6.9 0.0 2.4 2 0 0 2 2 2 0 ADP-ribosylation factor family AAA_13 PF13166.1 AIN96317.1 - 0.2 10.0 0.3 4.4 5.6 0.0 2.1 2 0 0 2 2 2 0 AAA domain cobW PF02492.14 AIN96317.1 - 1.9 7.8 3.9 17 4.7 0.0 2.9 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain Adaptin_N PF01602.15 AIN96319.1 - 0.012 13.9 2.2 0.5 8.6 0.1 2.3 2 1 0 2 2 2 0 Adaptin N terminal region HEAT PF02985.17 AIN96319.1 - 0.012 15.5 4.7 7.5 6.9 0.0 4.7 6 0 0 6 6 6 0 HEAT repeat Arm PF00514.18 AIN96319.1 - 0.24 11.2 3.7 3.8 7.4 0.3 3.9 3 1 1 4 4 4 0 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 AIN96319.1 - 1.3 9.3 15.3 4 7.8 4.3 4.2 1 1 2 3 3 3 0 HEAT repeats Hydrolase_like PF13242.1 AIN96320.1 - 0.04 13.6 0.1 0.084 12.5 0.1 1.5 1 0 0 1 1 1 0 HAD-hyrolase-like DUF2207 PF09972.4 AIN96320.1 - 0.17 10.4 0.7 0.3 9.6 0.5 1.4 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) PapD-like PF14874.1 AIN96321.1 - 4.6e-47 158.1 0.6 1.2e-46 156.8 0.4 1.8 1 0 0 1 1 1 1 Flagellar-associated PapD-like Nodulin-like PF06813.8 AIN96322.1 - 1.1e-15 57.6 13.5 1.1e-15 57.6 9.3 2.9 2 2 0 2 2 2 2 Nodulin-like MFS_1 PF07690.11 AIN96322.1 - 5.2e-09 35.2 40.5 3.1e-07 29.4 6.0 2.7 2 1 0 2 2 2 2 Major Facilitator Superfamily BLOC1_2 PF10046.4 AIN96324.1 - 0.00057 19.9 2.1 0.00098 19.2 1.4 1.3 1 0 0 1 1 1 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF4175 PF13779.1 AIN96324.1 - 0.036 11.7 2.4 0.04 11.6 1.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Ead_Ea22 PF13935.1 AIN96324.1 - 0.043 14.1 3.4 0.067 13.5 2.3 1.3 1 0 0 1 1 1 0 Ead/Ea22-like protein Leu_zip PF15294.1 AIN96324.1 - 0.094 11.8 6.4 0.19 10.7 4.5 1.5 1 1 0 1 1 1 0 Leucine zipper Spc7 PF08317.6 AIN96324.1 - 0.11 11.1 4.0 0.15 10.7 2.8 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein DivIC PF04977.10 AIN96324.1 - 0.18 11.3 4.9 0.074 12.5 0.5 2.1 1 1 1 2 2 2 0 Septum formation initiator HR1 PF02185.11 AIN96324.1 - 0.31 10.8 4.5 0.69 9.6 2.5 2.0 2 0 0 2 2 2 0 Hr1 repeat NYD-SP28_assoc PF14775.1 AIN96324.1 - 0.39 10.4 2.2 9.2 6.0 1.6 2.4 1 1 1 2 2 2 0 Sperm tail C-terminal domain DUF904 PF06005.7 AIN96324.1 - 3.3 8.0 9.2 27 5.1 6.5 2.3 1 1 0 1 1 1 0 Protein of unknown function (DUF904) IncA PF04156.9 AIN96324.1 - 5.7 6.4 9.5 11 5.5 6.6 1.4 1 1 0 1 1 1 0 IncA protein Ribosomal_L4 PF00573.17 AIN96325.1 - 5.8e-10 38.8 0.0 2e-09 37.1 0.0 1.8 1 1 0 1 1 1 1 Ribosomal protein L4/L1 family TruD PF01142.13 AIN96327.1 - 0.0024 16.5 0.0 0.0088 14.7 0.0 1.8 1 1 0 1 1 1 1 tRNA pseudouridine synthase D (TruD) SH3_9 PF14604.1 AIN96328.1 - 2.2e-10 39.9 0.0 6.3e-10 38.4 0.0 1.8 2 0 0 2 2 2 1 Variant SH3 domain SH3_1 PF00018.23 AIN96328.1 - 3.6e-10 39.0 0.0 7.5e-10 38.0 0.0 1.6 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 AIN96328.1 - 1.2e-09 37.4 0.0 5.6e-08 32.1 0.0 2.5 2 0 0 2 2 2 1 Variant SH3 domain Spectrin PF00435.16 AIN96328.1 - 0.45 10.8 6.1 4.6 7.5 0.6 2.7 2 0 0 2 2 2 0 Spectrin repeat IF-2B PF01008.12 AIN96329.1 - 6.7e-23 81.0 1.0 5.7e-18 64.8 0.4 3.0 2 2 0 2 2 2 2 Initiation factor 2 subunit family PITH PF06201.8 AIN96330.1 - 7.8e-26 90.6 0.0 9.4e-26 90.4 0.0 1.1 1 0 0 1 1 1 1 PITH domain Proteasome PF00227.21 AIN96331.1 - 4.7e-43 146.7 0.6 5.6e-43 146.4 0.4 1.1 1 0 0 1 1 1 1 Proteasome subunit DAP3 PF10236.4 AIN96332.1 - 2.4e-28 98.9 0.0 3.7e-28 98.3 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal death-associated protein 3 AAA_19 PF13245.1 AIN96332.1 - 0.0061 16.2 0.0 0.012 15.3 0.0 1.4 1 0 0 1 1 1 1 Part of AAA domain T2SE PF00437.15 AIN96332.1 - 0.011 14.6 0.0 0.015 14.2 0.0 1.1 1 0 0 1 1 1 0 Type II/IV secretion system protein Arch_ATPase PF01637.13 AIN96332.1 - 0.059 13.0 0.0 0.17 11.5 0.0 1.7 2 0 0 2 2 2 0 Archaeal ATPase AAA_16 PF13191.1 AIN96332.1 - 0.13 12.2 0.0 0.29 11.1 0.0 1.6 1 1 0 1 1 1 0 AAA ATPase domain Sulfate_tra_GLY PF13792.1 AIN96333.1 - 0.046 13.3 0.0 0.069 12.8 0.0 1.3 1 0 0 1 1 1 0 Sulfate transporter N-terminal domain with GLY motif Metallophos PF00149.23 AIN96334.1 - 0.13 11.6 0.0 0.21 10.9 0.0 1.3 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase Isochorismatase PF00857.15 AIN96335.1 - 1e-14 54.8 0.0 1.6e-14 54.2 0.0 1.3 1 1 0 1 1 1 1 Isochorismatase family DUF3024 PF11225.3 AIN96338.1 - 0.13 12.1 1.0 5.9 6.8 0.3 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF3024) Gmx_para_CXXCG PF09535.5 AIN96339.1 - 0.048 12.6 0.0 0.76 8.7 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (Gmx_para_CXXCG) Plus-3 PF03126.13 AIN96340.1 - 4.4e-12 45.9 0.0 8.6e-12 45.0 0.0 1.5 1 0 0 1 1 1 1 Plus-3 domain zf-C3HC4_3 PF13920.1 AIN96340.1 - 1.1e-06 28.2 21.1 1.7e-06 27.6 14.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Vps39_2 PF10367.4 AIN96340.1 - 0.04 14.0 4.6 0.088 12.9 3.2 1.6 1 0 0 1 1 1 0 Vacuolar sorting protein 39 domain 2 zf-C3HC4_2 PF13923.1 AIN96340.1 - 3.9 7.5 22.4 7.4 6.6 15.6 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Pkinase PF00069.20 AIN96343.1 - 1.1e-38 132.8 0.0 1.3e-17 63.8 0.0 3.5 2 2 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 AIN96343.1 - 5.9e-20 71.4 0.0 8.1e-12 44.7 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.18 AIN96343.1 - 0.0037 17.0 0.3 0.58 9.8 0.2 2.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family LRR_4 PF12799.2 AIN96345.1 - 3.3e-10 39.3 0.6 0.0014 18.1 0.0 3.3 4 0 0 4 4 4 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 AIN96345.1 - 2.7e-06 27.0 0.6 0.16 11.7 0.0 3.3 2 1 1 3 3 3 3 Leucine rich repeat LRR_1 PF00560.28 AIN96345.1 - 0.00014 21.3 2.0 1.3 9.3 0.0 5.0 5 0 0 5 5 5 2 Leucine Rich Repeat LRR_7 PF13504.1 AIN96345.1 - 0.11 12.7 7.7 8.1 7.1 0.1 4.9 5 0 0 5 5 5 0 Leucine rich repeat LRR_6 PF13516.1 AIN96345.1 - 1.7 8.9 3.6 34 4.9 0.0 4.4 5 0 0 5 5 5 0 Leucine Rich repeat UCH PF00443.24 AIN96348.1 - 4.1e-26 91.6 0.0 4.2e-25 88.3 0.0 2.2 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 AIN96348.1 - 0.056 12.8 0.0 4.8 6.5 0.0 2.8 2 0 0 2 2 2 0 Ubiquitin carboxyl-terminal hydrolase DUF2173 PF09941.4 AIN96348.1 - 0.4 10.6 1.9 3.9 7.4 0.5 2.5 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2173) AAA PF00004.24 AIN96350.1 - 4.3e-45 153.1 0.0 8e-45 152.2 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 AIN96350.1 - 7.1e-09 35.5 0.1 2.2e-08 33.9 0.0 1.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 AIN96350.1 - 5e-07 29.8 0.2 2.1e-05 24.5 0.0 2.3 1 1 1 2 2 2 1 AAA ATPase domain AAA_2 PF07724.9 AIN96350.1 - 1e-06 28.7 0.0 2.3e-06 27.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.1 AIN96350.1 - 3.6e-06 27.1 0.4 0.00015 21.8 0.3 2.4 1 1 0 1 1 1 1 AAA domain DUF815 PF05673.8 AIN96350.1 - 6.1e-05 22.0 0.0 0.0001 21.3 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_28 PF13521.1 AIN96350.1 - 0.00019 21.4 0.0 0.00034 20.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 AIN96350.1 - 0.00028 20.5 0.1 0.00061 19.4 0.0 1.5 1 0 0 1 1 1 1 Part of AAA domain AAA_17 PF13207.1 AIN96350.1 - 0.00051 20.8 0.0 0.001 19.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.7 AIN96350.1 - 0.00052 19.1 0.0 0.0011 18.1 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus NACHT PF05729.7 AIN96350.1 - 0.00054 19.6 0.4 0.03 13.9 0.0 3.1 2 1 1 3 3 3 1 NACHT domain AAA_14 PF13173.1 AIN96350.1 - 0.00061 19.6 0.0 0.0014 18.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.1 AIN96350.1 - 0.0008 18.8 0.7 0.032 13.6 0.0 2.2 1 1 1 2 2 2 1 AAA domain AAA_3 PF07726.6 AIN96350.1 - 0.0019 17.7 0.0 0.0068 16.0 0.0 1.9 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) NTPase_1 PF03266.10 AIN96350.1 - 0.0027 17.4 0.7 0.0082 15.8 0.1 2.2 3 1 0 3 3 2 1 NTPase AAA_33 PF13671.1 AIN96350.1 - 0.004 17.0 0.0 0.0074 16.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.1 AIN96350.1 - 0.0052 16.3 0.0 0.012 15.2 0.0 1.6 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 AIN96350.1 - 0.0053 15.8 0.0 0.0088 15.1 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin Mg_chelatase PF01078.16 AIN96350.1 - 0.0063 15.6 0.1 0.015 14.4 0.0 1.6 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI Arch_ATPase PF01637.13 AIN96350.1 - 0.0066 16.1 0.1 0.046 13.4 0.0 2.1 1 1 1 2 2 2 1 Archaeal ATPase AAA_18 PF13238.1 AIN96350.1 - 0.0087 16.3 0.0 0.016 15.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.1 AIN96350.1 - 0.0099 15.4 0.1 0.022 14.3 0.1 1.5 1 0 0 1 1 1 1 AAA domain TIP49 PF06068.8 AIN96350.1 - 0.011 14.4 0.1 0.028 13.1 0.0 1.5 1 1 0 2 2 2 0 TIP49 C-terminus IstB_IS21 PF01695.12 AIN96350.1 - 0.014 14.8 0.0 0.024 14.0 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein Sigma54_activat PF00158.21 AIN96350.1 - 0.016 14.7 0.1 0.76 9.2 0.0 2.4 2 0 0 2 2 2 0 Sigma-54 interaction domain Bac_DnaA PF00308.13 AIN96350.1 - 0.017 14.7 0.0 0.028 14.0 0.0 1.4 1 0 0 1 1 1 0 Bacterial dnaA protein RNA_helicase PF00910.17 AIN96350.1 - 0.022 14.9 0.0 0.043 14.0 0.0 1.5 1 0 0 1 1 1 0 RNA helicase ABC_tran PF00005.22 AIN96350.1 - 0.039 14.2 0.0 0.14 12.5 0.0 2.1 1 1 0 1 1 1 0 ABC transporter NB-ARC PF00931.17 AIN96350.1 - 0.052 12.3 0.0 0.37 9.5 0.0 2.0 2 0 0 2 2 2 0 NB-ARC domain Histone PF00125.19 AIN96350.1 - 0.052 13.6 0.2 0.2 11.7 0.0 2.1 3 0 0 3 3 1 0 Core histone H2A/H2B/H3/H4 cobW PF02492.14 AIN96350.1 - 0.067 12.6 0.0 0.18 11.2 0.0 1.7 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_11 PF13086.1 AIN96350.1 - 0.068 12.7 0.0 0.15 11.5 0.0 1.6 1 1 1 2 2 2 0 AAA domain KaiC PF06745.8 AIN96350.1 - 0.083 12.0 0.2 0.73 8.9 0.0 2.2 2 0 0 2 2 2 0 KaiC UPF0079 PF02367.12 AIN96350.1 - 0.097 12.2 0.0 0.19 11.3 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 Lactamase_B PF00753.22 AIN96351.1 - 4.5e-13 49.2 1.0 6.8e-13 48.7 0.7 1.3 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 AIN96351.1 - 0.00013 21.5 0.3 0.00019 21.0 0.2 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain K1377 PF15352.1 AIN96352.1 - 0.36 8.6 0.0 0.6 7.9 0.0 1.2 1 0 0 1 1 1 0 Susceptibility to monomelic amyotrophy tRNA-synt_1e PF01406.14 AIN96354.1 - 8.8e-112 373.1 0.0 1.3e-111 372.5 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1g PF09334.6 AIN96354.1 - 0.00013 20.7 0.4 0.01 14.4 0.0 3.1 3 0 0 3 3 3 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.17 AIN96354.1 - 0.0027 15.7 0.0 0.047 11.6 0.0 2.6 3 0 0 3 3 3 1 tRNA synthetases class I (I, L, M and V) tRNA-synt_1c PF00749.16 AIN96354.1 - 0.036 12.7 0.8 0.12 11.0 0.0 2.2 2 0 0 2 2 2 0 tRNA synthetases class I (E and Q), catalytic domain Helicase_C PF00271.26 AIN96355.1 - 1.8e-06 27.7 0.0 2e-05 24.3 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain HA2 PF04408.18 AIN96355.1 - 1.7e-05 24.7 0.0 7.1e-05 22.7 0.0 2.0 1 0 0 1 1 1 1 Helicase associated domain (HA2) DEAD PF00270.24 AIN96355.1 - 0.00047 19.6 0.0 0.0025 17.3 0.0 2.0 1 1 0 1 1 1 1 DEAD/DEAH box helicase zf-C2H2_jaz PF12171.3 AIN96355.1 - 0.03 14.4 2.1 0.063 13.4 1.4 1.6 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 AIN96355.1 - 1.8 8.9 5.3 4.4 7.6 3.7 1.8 1 0 0 1 1 1 0 Zinc-finger of C2H2 type SET PF00856.23 AIN96356.1 - 4.9e-08 33.4 0.3 0.0032 17.7 0.0 3.3 2 1 0 2 2 2 2 SET domain DUF681 PF05080.7 AIN96356.1 - 0.052 13.9 0.2 0.2 12.1 0.1 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF681) Orn_Arg_deC_N PF02784.11 AIN96357.1 - 2e-73 246.6 0.0 2.8e-73 246.1 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.17 AIN96357.1 - 8.7e-37 125.3 0.0 4e-36 123.2 0.0 2.1 2 0 0 2 2 2 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain KxDL PF10241.4 AIN96358.1 - 0.00025 20.8 1.6 0.00025 20.8 1.1 5.9 4 2 1 5 5 5 2 Uncharacterized conserved protein SAC3_GANP PF03399.11 AIN96359.1 - 6.4e-06 25.8 0.5 0.0012 18.3 0.2 2.2 2 0 0 2 2 2 2 SAC3/GANP/Nin1/mts3/eIF-3 p25 family BUD22 PF09073.5 AIN96359.1 - 6.6 5.6 11.8 0.3 10.0 1.8 2.3 2 0 0 2 2 2 0 BUD22 ATPase_gene1 PF09527.5 AIN96360.1 - 0.18 11.6 2.2 0.31 10.8 1.6 1.4 1 0 0 1 1 1 0 Putative F0F1-ATPase subunit (ATPase_gene1) Myotub-related PF06602.9 AIN96361.1 - 2.5e-50 171.2 0.0 1.5e-27 96.3 0.1 3.5 3 1 0 3 3 3 2 Myotubularin-like phosphatase domain MAP65_ASE1 PF03999.7 AIN96361.1 - 8.7 4.8 0.6 23 3.4 0.4 1.6 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) NOT2_3_5 PF04153.13 AIN96364.1 - 4.4e-31 107.5 0.4 4.4e-31 107.5 0.3 3.6 3 1 0 3 3 3 1 NOT2 / NOT3 / NOT5 family Sigma_reg_C PF13791.1 AIN96364.1 - 7.4 6.5 8.9 10 6.1 2.8 2.4 2 0 0 2 2 2 0 Sigma factor regulator C-terminal FHIPEP PF00771.15 AIN96364.1 - 9.5 4.4 14.6 16 3.6 10.1 1.3 1 0 0 1 1 1 0 FHIPEP family GST_N_3 PF13417.1 AIN96365.1 - 1.2e-09 38.2 0.0 3.2e-09 36.8 0.0 1.8 1 1 1 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 AIN96365.1 - 6.6e-09 35.8 0.0 1.4e-08 34.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 AIN96365.1 - 1.7e-07 31.1 0.0 4.1e-07 29.8 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 AIN96365.1 - 0.00042 20.7 0.1 0.069 13.6 0.0 2.8 2 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 AIN96365.1 - 0.026 14.4 0.0 0.071 13.1 0.0 1.9 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain ETRAMP PF09716.5 AIN96366.1 - 0.061 13.2 0.0 0.15 12.0 0.0 1.7 1 0 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) PUF PF00806.14 AIN96367.1 - 9.4e-34 113.0 5.7 0.00015 21.0 0.0 7.6 7 0 0 7 7 7 7 Pumilio-family RNA binding repeat NAD_binding_10 PF13460.1 AIN96368.1 - 0.0041 17.1 0.7 0.012 15.6 0.1 2.1 2 1 0 2 2 2 1 NADH(P)-binding DapB_N PF01113.15 AIN96368.1 - 0.0063 16.4 0.1 0.02 14.8 0.0 1.9 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus NmrA PF05368.8 AIN96368.1 - 0.012 14.8 0.2 0.022 14.0 0.1 1.4 1 0 0 1 1 1 0 NmrA-like family DXP_reductoisom PF02670.11 AIN96368.1 - 0.055 13.9 1.4 0.096 13.2 0.1 2.0 2 0 0 2 2 2 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase NAD_binding_4 PF07993.7 AIN96368.1 - 0.055 12.3 0.4 0.14 11.0 0.0 1.9 3 0 0 3 3 3 0 Male sterility protein Epimerase PF01370.16 AIN96368.1 - 0.084 12.2 0.1 0.16 11.3 0.0 1.5 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family S1-P1_nuclease PF02265.11 AIN96369.1 - 6.5e-55 186.4 0.0 7.8e-55 186.2 0.0 1.1 1 0 0 1 1 1 1 S1/P1 Nuclease DUF866 PF05907.8 AIN96371.1 - 1.6e-25 89.4 0.0 2e-25 89.1 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF866) Yippee-Mis18 PF03226.9 AIN96371.1 - 0.038 14.0 0.0 6.5 6.8 0.0 2.3 2 0 0 2 2 2 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly Elf1 PF05129.8 AIN96371.1 - 0.042 13.5 0.4 0.095 12.4 0.2 1.5 1 1 0 1 1 1 0 Transcription elongation factor Elf1 like DUF3222 PF11519.3 AIN96371.1 - 0.072 13.0 0.2 0.3 11.0 0.0 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3222) Bromodomain PF00439.20 AIN96372.1 - 0.05 13.5 0.0 0.13 12.2 0.0 1.7 1 1 0 1 1 1 0 Bromodomain PHTB1_C PF14728.1 AIN96374.1 - 0.033 13.0 0.0 0.055 12.2 0.0 1.2 1 0 0 1 1 1 0 PTHB1 C-terminus WW PF00397.21 AIN96380.1 - 6.2e-08 32.3 0.1 1.3e-07 31.2 0.1 1.6 1 0 0 1 1 1 1 WW domain ATP-synt_F PF01990.12 AIN96381.1 - 1.6e-35 121.3 0.1 1.9e-35 121.1 0.0 1.1 1 0 0 1 1 1 1 ATP synthase (F/14-kDa) subunit PGI PF00342.14 AIN96382.1 - 3.2e-237 787.6 1.3 3.7e-237 787.4 0.9 1.0 1 0 0 1 1 1 1 Phosphoglucose isomerase OsmC PF02566.14 AIN96383.1 - 0.015 15.4 0.0 0.025 14.7 0.0 1.3 1 0 0 1 1 1 0 OsmC-like protein DUF1604 PF07713.8 AIN96383.1 - 3.7 7.4 6.8 6.9 6.5 4.7 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1604) DUF4407 PF14362.1 AIN96384.1 - 2.7 6.8 5.9 5 5.9 4.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) TPR_11 PF13414.1 AIN96385.1 - 2.8e-07 30.1 16.2 0.0054 16.3 2.1 5.9 6 1 0 6 6 6 2 TPR repeat TPR_19 PF14559.1 AIN96385.1 - 0.0084 16.4 27.4 0.015 15.5 0.8 6.6 5 1 1 6 6 6 2 Tetratricopeptide repeat TPR_1 PF00515.23 AIN96385.1 - 0.02 14.5 8.3 0.65 9.7 0.7 5.7 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_2 PF07719.12 AIN96385.1 - 0.15 12.0 24.9 0.081 12.8 1.8 8.0 9 2 2 11 11 11 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 AIN96385.1 - 0.48 10.3 5.8 0.2 11.5 0.5 3.0 3 0 0 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat TPR_8 PF13181.1 AIN96385.1 - 1.1 9.1 6.8 34 4.5 0.3 5.3 6 0 0 6 6 6 0 Tetratricopeptide repeat FUSC_2 PF13515.1 AIN96386.1 - 3.9e-12 46.1 8.8 3.9e-12 46.1 6.1 2.6 2 0 0 2 2 2 1 Fusaric acid resistance protein-like Activator-TraM PF11657.3 AIN96386.1 - 0.16 11.4 0.0 0.46 9.9 0.0 1.7 1 0 0 1 1 1 0 Transcriptional activator TraM DUF939 PF06081.6 AIN96386.1 - 4.4 7.1 10.0 0.35 10.7 2.5 2.2 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF939) FUSC_2 PF13515.1 AIN96387.1 - 3.4e-10 39.9 4.4 3.4e-10 39.9 3.0 2.5 2 0 0 2 2 2 1 Fusaric acid resistance protein-like ALMT PF11744.3 AIN96387.1 - 0.029 13.0 3.9 0.024 13.2 0.2 2.2 2 0 0 2 2 2 0 Aluminium activated malate transporter Sulfatase PF00884.18 AIN96388.1 - 5.7e-05 22.4 0.1 0.0014 17.8 0.0 2.2 2 0 0 2 2 2 2 Sulfatase Phosphodiest PF01663.17 AIN96388.1 - 0.056 12.7 0.0 3.3 6.9 0.0 2.6 2 1 0 2 2 2 0 Type I phosphodiesterase / nucleotide pyrophosphatase TPR_11 PF13414.1 AIN96389.1 - 2e-18 65.7 17.5 1.7e-11 43.5 0.2 5.2 3 1 3 6 6 6 5 TPR repeat TPR_1 PF00515.23 AIN96389.1 - 1.7e-17 62.2 11.9 5.7e-05 22.5 0.0 6.0 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_2 PF07719.12 AIN96389.1 - 1.9e-17 61.7 19.4 0.0014 18.4 0.1 8.2 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_14 PF13428.1 AIN96389.1 - 1.9e-12 46.6 17.7 6.7e-05 23.1 0.1 7.5 7 2 2 9 9 6 3 Tetratricopeptide repeat TPR_16 PF13432.1 AIN96389.1 - 1e-11 45.1 19.9 0.0003 21.3 0.9 6.2 3 1 2 5 5 5 3 Tetratricopeptide repeat TPR_8 PF13181.1 AIN96389.1 - 1.5e-11 43.1 4.2 0.0048 16.5 0.0 5.9 5 1 1 6 6 5 2 Tetratricopeptide repeat TPR_19 PF14559.1 AIN96389.1 - 3e-11 43.5 7.0 4.3e-05 23.7 0.1 5.0 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_12 PF13424.1 AIN96389.1 - 1e-07 31.7 28.6 0.00039 20.3 0.8 6.7 3 1 5 8 8 8 6 Tetratricopeptide repeat TPR_7 PF13176.1 AIN96389.1 - 3e-05 23.4 15.0 0.11 12.4 0.2 6.3 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_15 PF13429.1 AIN96389.1 - 0.00012 21.2 7.5 0.00019 20.6 4.4 2.0 1 1 1 2 2 2 1 Tetratricopeptide repeat Apc3 PF12895.2 AIN96389.1 - 0.00025 21.1 15.6 0.011 15.9 0.2 5.4 5 1 1 6 6 6 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.1 AIN96389.1 - 0.00056 19.9 6.0 0.11 12.7 0.2 5.0 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_10 PF13374.1 AIN96389.1 - 0.002 17.9 7.5 0.16 11.9 0.2 4.3 3 0 0 3 3 3 1 Tetratricopeptide repeat APC8 PF04049.8 AIN96389.1 - 0.0079 15.9 0.0 0.059 13.0 0.0 2.3 1 1 0 1 1 1 1 Anaphase promoting complex subunit 8 / Cdc23 TPR_6 PF13174.1 AIN96389.1 - 0.018 15.4 6.0 0.93 10.0 0.0 5.0 6 1 0 6 6 5 0 Tetratricopeptide repeat TPR_9 PF13371.1 AIN96389.1 - 0.03 14.1 16.9 0.48 10.3 0.1 5.6 4 1 2 6 6 6 0 Tetratricopeptide repeat FAT PF02259.18 AIN96389.1 - 0.17 10.8 0.2 0.85 8.5 0.2 2.1 1 1 0 1 1 1 0 FAT domain Aminotran_1_2 PF00155.16 AIN96391.1 - 3.4e-32 111.7 0.0 4.4e-32 111.4 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II PriCT_2 PF08707.6 AIN96392.1 - 3.8e-15 55.5 0.1 9.3e-15 54.2 0.1 1.7 1 0 0 1 1 1 1 Primase C terminal 2 (PriCT-2) PBP1_TM PF14812.1 AIN96392.1 - 0.68 10.2 2.8 1.3 9.3 1.9 1.4 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal BTV_NS2 PF04514.7 AIN96393.1 - 1.5 7.6 7.8 2.2 7.0 5.4 1.2 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 Metallophos PF00149.23 AIN96394.1 - 3.9e-36 124.3 0.0 8.7e-36 123.1 0.0 1.6 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase zf-TRAF PF02176.13 AIN96394.1 - 2.9e-05 24.3 2.6 2.9e-05 24.3 1.8 3.1 1 1 2 3 3 3 1 TRAF-type zinc finger EF-hand_1 PF00036.27 AIN96394.1 - 0.002 17.2 0.0 0.041 13.1 0.0 2.9 3 0 0 3 3 3 1 EF hand EF-hand_7 PF13499.1 AIN96394.1 - 0.0051 16.9 0.1 0.79 9.9 0.0 3.9 4 1 0 4 4 4 1 EF-hand domain pair Metallophos_2 PF12850.2 AIN96394.1 - 0.0058 16.4 0.0 0.011 15.5 0.0 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain zinc_ribbon_2 PF13240.1 AIN96394.1 - 0.0073 15.7 3.6 0.0073 15.7 2.5 2.4 2 0 0 2 2 2 1 zinc-ribbon domain EF-hand_6 PF13405.1 AIN96394.1 - 0.021 14.6 0.6 1.2 9.1 0.0 3.4 3 0 0 3 3 3 0 EF-hand domain EF-hand_8 PF13833.1 AIN96394.1 - 0.028 14.0 0.3 1.8 8.2 0.0 3.5 3 1 1 4 4 4 0 EF-hand domain pair zf-tcix PF14952.1 AIN96394.1 - 0.4 10.0 7.0 11 5.4 0.4 3.7 3 0 0 3 3 3 0 Putative treble-clef, zinc-finger, Zn-binding DUF1448 PF07289.6 AIN96396.1 - 1.5e-134 448.2 0.0 1.7e-134 448.0 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1448) Voldacs PF03517.8 AIN96396.1 - 0.00022 21.0 0.4 0.55 10.0 0.0 2.7 3 0 0 3 3 3 2 Regulator of volume decrease after cellular swelling Vps36_ESCRT-II PF11605.3 AIN96396.1 - 0.00047 19.9 0.0 0.27 11.0 0.0 2.3 2 0 0 2 2 2 2 Vacuolar protein sorting protein 36 Vps36 bPH_3 PF14470.1 AIN96396.1 - 0.0051 17.0 0.0 2.7 8.3 0.0 2.3 2 0 0 2 2 2 2 Bacterial PH domain Viral_env_E26 PF11050.3 AIN96397.1 - 0.013 14.6 0.0 0.02 14.0 0.0 1.3 1 0 0 1 1 1 0 Virus envelope protein E26 DUF2333 PF10095.4 AIN96397.1 - 0.038 12.6 0.0 0.04 12.5 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2333) LRR_6 PF13516.1 AIN96398.1 - 8.6e-23 77.8 11.1 0.046 13.8 0.1 11.4 10 1 1 11 11 11 7 Leucine Rich repeat LRR_4 PF12799.2 AIN96398.1 - 2.1e-15 55.9 2.7 0.01 15.4 0.0 6.6 5 1 1 6 6 6 6 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 AIN96398.1 - 6.3e-09 34.6 12.1 1.3 9.3 0.0 8.7 10 0 0 10 10 10 4 Leucine Rich Repeat LRR_8 PF13855.1 AIN96398.1 - 0.00015 21.4 13.7 0.14 11.9 0.4 6.3 6 1 1 7 7 7 2 Leucine rich repeat LRR_7 PF13504.1 AIN96398.1 - 0.0026 17.6 23.6 16 6.2 0.0 9.0 10 0 0 10 10 10 1 Leucine rich repeat Uds1 PF15456.1 AIN96398.1 - 0.2 11.6 21.0 0.38 10.7 3.2 2.5 1 1 1 2 2 2 0 Up-regulated During Septation DUF962 PF06127.6 AIN96399.1 - 5.9e-24 83.7 0.2 6.7e-24 83.6 0.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF962) DUF2453 PF10507.4 AIN96399.1 - 0.033 13.9 1.4 0.1 12.4 1.0 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF2453) DUF3040 PF11239.3 AIN96399.1 - 0.17 11.9 0.7 0.24 11.4 0.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3040) CBP4 PF07960.6 AIN96399.1 - 0.9 9.1 2.6 2.9 7.5 0.1 2.3 1 1 0 2 2 2 0 CBP4 Gly-zipper_YMGG PF13441.1 AIN96399.1 - 6.5 6.3 9.4 15 5.2 6.5 1.5 1 1 0 1 1 1 0 YMGG-like Gly-zipper Gly-zipper_Omp PF13488.1 AIN96399.1 - 9.9 5.8 9.0 19 4.9 6.2 1.5 1 1 0 1 1 1 0 Glycine zipper DUF962 PF06127.6 AIN96400.1 - 9.4e-26 89.5 0.1 1.1e-25 89.3 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF962) UPF0126 PF03458.8 AIN96400.1 - 0.059 13.0 2.6 0.089 12.4 1.8 1.3 1 1 0 1 1 1 0 UPF0126 domain RNase_H2-Ydr279 PF09468.5 AIN96401.1 - 6.2e-11 42.0 0.0 6.2e-05 22.3 0.0 2.7 2 1 0 2 2 2 2 Ydr279p protein family (RNase H2 complex component) DUF1292 PF06949.6 AIN96402.1 - 0.037 14.3 0.4 0.095 13.0 0.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1292) LRR_4 PF12799.2 AIN96403.1 - 7.1e-34 114.8 11.7 0.0013 18.3 0.5 12.5 3 2 15 18 18 18 14 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 AIN96403.1 - 3.5e-29 100.3 8.7 0.00071 19.2 0.5 8.7 3 2 7 11 11 11 10 Leucine rich repeat LRR_1 PF00560.28 AIN96403.1 - 1.2e-18 64.2 0.0 4.3 7.7 0.0 15.0 17 0 0 17 17 17 3 Leucine Rich Repeat LRRNT_2 PF08263.7 AIN96403.1 - 0.00047 20.0 0.4 0.0017 18.2 0.3 2.0 1 0 0 1 1 1 1 Leucine rich repeat N-terminal domain LRR_6 PF13516.1 AIN96403.1 - 0.036 14.1 5.7 48 4.4 0.0 6.3 5 0 0 5 5 5 0 Leucine Rich repeat LRR_7 PF13504.1 AIN96403.1 - 0.057 13.6 9.5 9.5 6.9 0.1 6.9 8 0 0 8 8 8 0 Leucine rich repeat LRRNT_2 PF08263.7 AIN96404.1 - 0.00031 20.6 0.4 0.00084 19.2 0.3 1.8 1 0 0 1 1 1 1 Leucine rich repeat N-terminal domain DnaJ PF00226.26 AIN96406.1 - 7.9e-15 54.3 0.0 1.9e-14 53.1 0.0 1.7 1 0 0 1 1 1 1 DnaJ domain zf-C3HC4_3 PF13920.1 AIN96406.1 - 1.8 8.2 16.6 3.9 7.2 11.5 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) PDZ PF00595.19 AIN96407.1 - 0.02 15.0 0.0 0.058 13.5 0.0 1.8 1 0 0 1 1 1 0 PDZ domain (Also known as DHR or GLGF) PDZ_2 PF13180.1 AIN96407.1 - 0.035 13.9 0.0 0.09 12.6 0.0 1.6 1 0 0 1 1 1 0 PDZ domain Oxidored_FMN PF00724.15 AIN96408.1 - 3.4e-80 269.5 0.0 1.1e-79 267.9 0.0 1.7 1 1 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family His_biosynth PF00977.16 AIN96408.1 - 0.023 13.9 0.0 0.039 13.2 0.0 1.4 1 0 0 1 1 1 0 Histidine biosynthesis protein Oxidored_FMN PF00724.15 AIN96409.1 - 1.2e-140 468.3 0.0 4.2e-79 266.0 0.0 2.1 2 0 0 2 2 2 2 NADH:flavin oxidoreductase / NADH oxidase family Dus PF01207.12 AIN96409.1 - 0.03 13.1 0.0 2.7 6.7 0.0 2.6 2 0 0 2 2 2 0 Dihydrouridine synthase (Dus) DUF2404 PF10296.4 AIN96411.1 - 4.5e-20 71.5 0.0 7.5e-20 70.8 0.0 1.4 1 0 0 1 1 1 1 Putative integral membrane protein conserved region (DUF2404) Herpes_UL32 PF06070.6 AIN96411.1 - 0.011 14.2 2.1 0.018 13.5 1.5 1.3 1 0 0 1 1 1 0 Herpesvirus large structural phosphoprotein UL32 DUF2404 PF10296.4 AIN96412.1 - 1.1e-24 86.3 0.0 2.1e-24 85.4 0.0 1.5 1 0 0 1 1 1 1 Putative integral membrane protein conserved region (DUF2404) CSD PF00313.17 AIN96413.1 - 0.0002 21.0 0.0 0.0047 16.6 0.0 2.5 2 0 0 2 2 2 1 'Cold-shock' DNA-binding domain ABC_tran PF00005.22 AIN96414.1 - 5.5e-12 46.1 0.0 1.5e-05 25.2 0.0 2.5 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 AIN96414.1 - 0.00026 21.0 0.0 0.33 10.8 0.0 2.2 2 0 0 2 2 2 2 AAA domain DUF258 PF03193.11 AIN96414.1 - 0.0029 16.7 0.5 0.0056 15.8 0.3 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_25 PF13481.1 AIN96414.1 - 0.0055 16.1 0.1 0.017 14.5 0.1 1.8 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 AIN96414.1 - 0.0068 16.4 0.6 0.034 14.1 0.4 2.2 1 0 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.1 AIN96414.1 - 0.013 15.0 0.1 0.032 13.7 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_30 PF13604.1 AIN96414.1 - 0.021 14.4 0.0 0.051 13.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.1 AIN96414.1 - 0.068 13.3 0.0 1.4 9.1 0.1 2.7 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.9 AIN96414.1 - 0.16 11.7 0.1 0.39 10.4 0.1 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) ABC_ATPase PF09818.4 AIN96414.1 - 0.27 9.7 0.1 0.46 8.9 0.0 1.2 1 0 0 1 1 1 0 Predicted ATPase of the ABC class MMR_HSR1 PF01926.18 AIN96414.1 - 0.27 11.1 0.0 0.64 9.9 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase Guanylate_kin PF00625.16 AIN96414.1 - 0.31 10.4 0.0 0.55 9.6 0.0 1.3 1 0 0 1 1 1 0 Guanylate kinase AAA_15 PF13175.1 AIN96414.1 - 0.48 9.4 0.0 11 4.9 0.0 2.0 2 0 0 2 2 2 0 AAA ATPase domain AAA_10 PF12846.2 AIN96414.1 - 0.61 9.4 0.6 1.3 8.4 0.4 1.5 1 0 0 1 1 1 0 AAA-like domain CENP-B_dimeris PF09026.5 AIN96415.1 - 0.083 13.1 1.7 0.29 11.4 1.1 1.8 2 0 0 2 2 2 0 Centromere protein B dimerisation domain DUF3639 PF12341.3 AIN96417.1 - 7.6e-09 35.4 0.6 2.3e-08 33.8 0.4 1.9 1 0 0 1 1 1 1 Protein of unknown function (DUF3639) WD40 PF00400.27 AIN96417.1 - 9.5e-05 22.1 4.4 0.74 9.7 0.0 5.3 5 1 0 5 5 5 2 WD domain, G-beta repeat DUF2121 PF09894.4 AIN96417.1 - 0.091 12.0 0.0 0.2 10.9 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2121) SNARE_assoc PF09335.6 AIN96418.1 - 1.1e-21 77.3 6.3 2.4e-21 76.2 4.3 1.6 1 0 0 1 1 1 1 SNARE associated Golgi protein zf-C3HC4_2 PF13923.1 AIN96419.1 - 4.5e-07 29.7 6.2 4.5e-07 29.7 4.3 3.1 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 AIN96419.1 - 8.5e-06 25.3 4.5 8.5e-06 25.3 3.1 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 AIN96419.1 - 0.00015 21.5 7.2 0.00015 21.5 5.0 2.6 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.1 AIN96419.1 - 0.00082 19.0 7.4 0.00082 19.0 5.1 2.6 3 0 0 3 3 3 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 AIN96419.1 - 0.0017 18.0 6.0 0.0066 16.1 4.2 2.1 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_2 PF13639.1 AIN96419.1 - 0.0017 18.1 9.7 0.0017 18.1 6.7 3.2 3 0 0 3 3 3 1 Ring finger domain Peptidase_M1 PF01433.15 AIN96420.1 - 3.4e-67 227.2 0.0 5.9e-48 163.8 0.0 3.0 2 1 0 2 2 2 2 Peptidase family M1 Peptidase_MA_2 PF13485.1 AIN96420.1 - 1.2e-10 41.5 0.0 2.4e-10 40.5 0.0 1.5 1 0 0 1 1 1 1 Peptidase MA superfamily FYVE PF01363.16 AIN96421.1 - 0.13 12.2 7.1 4.4 7.2 0.1 2.5 2 0 0 2 2 2 0 FYVE zinc finger Prok-RING_2 PF14445.1 AIN96421.1 - 0.32 10.9 4.5 0.96 9.4 3.1 1.8 1 0 0 1 1 1 0 Prokaryotic RING finger family 2 Methyltransf_31 PF13847.1 AIN96422.1 - 1.6e-14 53.7 0.1 2.3e-14 53.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 AIN96422.1 - 1.6e-12 47.1 0.0 2.7e-12 46.4 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_18 PF12847.2 AIN96422.1 - 2e-11 44.4 0.1 3.6e-11 43.6 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain PRMT5 PF05185.11 AIN96422.1 - 3.9e-10 39.2 0.0 4.9e-10 38.9 0.0 1.1 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase Methyltransf_26 PF13659.1 AIN96422.1 - 1.9e-09 37.6 0.0 4.3e-09 36.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 AIN96422.1 - 1.3e-08 35.1 0.0 3.6e-08 33.7 0.0 1.7 1 1 1 2 2 1 1 Methyltransferase domain MTS PF05175.9 AIN96422.1 - 3.7e-08 32.9 0.2 6.1e-08 32.2 0.2 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_23 PF13489.1 AIN96422.1 - 9.6e-08 31.9 0.0 2.1e-07 30.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 AIN96422.1 - 5.5e-07 29.8 0.0 1.7e-06 28.2 0.0 1.9 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_9 PF08003.6 AIN96422.1 - 4.5e-06 25.6 0.0 6.1e-06 25.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_12 PF08242.7 AIN96422.1 - 5e-06 26.9 0.0 1e-05 25.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 AIN96422.1 - 2.2e-05 23.6 0.1 3.5e-05 23.0 0.1 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase TehB PF03848.9 AIN96422.1 - 2.8e-05 23.3 0.7 5.8e-05 22.3 0.5 1.6 1 1 0 1 1 1 1 Tellurite resistance protein TehB FtsJ PF01728.14 AIN96422.1 - 0.0022 18.0 0.0 0.004 17.1 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_32 PF13679.1 AIN96422.1 - 0.0034 17.0 0.0 0.0059 16.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 AIN96422.1 - 0.0051 15.9 0.1 0.0079 15.3 0.1 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Met_10 PF02475.11 AIN96422.1 - 0.0058 16.2 0.0 0.0088 15.6 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_4 PF02390.12 AIN96422.1 - 0.018 14.1 0.0 0.031 13.3 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase NodS PF05401.6 AIN96422.1 - 0.02 14.2 0.1 0.031 13.6 0.1 1.2 1 0 0 1 1 1 0 Nodulation protein S (NodS) PCMT PF01135.14 AIN96422.1 - 0.025 14.1 0.0 0.036 13.5 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_24 PF13578.1 AIN96422.1 - 0.052 14.3 0.0 0.12 13.2 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain SET PF00856.23 AIN96425.1 - 2.4e-07 31.2 0.5 8.9e-07 29.3 0.1 2.0 2 0 0 2 2 2 1 SET domain zf-MYND PF01753.13 AIN96425.1 - 1.1e-05 25.2 5.8 1.1e-05 25.2 4.0 2.8 2 0 0 2 2 2 1 MYND finger TPR_11 PF13414.1 AIN96425.1 - 0.0037 16.8 0.7 0.028 14.0 0.2 2.4 1 1 1 2 2 2 1 TPR repeat TPR_1 PF00515.23 AIN96425.1 - 0.0072 15.9 0.3 2.1 8.1 0.1 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.12 AIN96425.1 - 0.017 15.0 0.1 0.3 11.1 0.2 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat RNase_H2_suC PF08615.6 AIN96426.1 - 1.9e-09 37.4 0.0 2.7e-09 36.9 0.0 1.2 1 0 0 1 1 1 1 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) FAM91_C PF14648.1 AIN96427.1 - 2.5e-153 511.1 0.0 3.1e-153 510.8 0.0 1.1 1 0 0 1 1 1 1 FAM91 C-terminus FAM91_N PF14647.1 AIN96427.1 - 1.5e-109 365.8 0.2 2.4e-109 365.1 0.1 1.3 1 0 0 1 1 1 1 FAM91 N-terminus Vps39_2 PF10367.4 AIN96428.1 - 9.4e-25 86.9 0.6 2.2e-24 85.7 0.4 1.7 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 CNH PF00780.17 AIN96428.1 - 2.9e-08 33.4 0.0 4.6e-08 32.8 0.0 1.3 1 0 0 1 1 1 1 CNH domain Vps39_1 PF10366.4 AIN96428.1 - 5.6e-06 26.3 0.1 2.6e-05 24.1 0.0 2.1 2 0 0 2 2 2 1 Vacuolar sorting protein 39 domain 1 Clathrin PF00637.15 AIN96428.1 - 0.00015 21.3 0.0 0.014 14.9 0.0 2.5 2 0 0 2 2 2 1 Region in Clathrin and VPS Rad50_zn_hook PF04423.9 AIN96428.1 - 0.096 12.1 1.0 0.3 10.5 0.1 2.1 2 0 0 2 2 2 0 Rad50 zinc hook motif Abhydrolase_5 PF12695.2 AIN96429.1 - 5.9e-09 35.8 0.0 1.1e-08 34.9 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 AIN96429.1 - 0.0024 17.7 0.5 0.076 12.8 0.1 2.6 2 1 0 2 2 2 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 AIN96429.1 - 0.028 13.6 0.0 0.048 12.8 0.0 1.4 1 0 0 1 1 1 0 Prolyl oligopeptidase family Rep_trans PF02486.14 AIN96430.1 - 0.0063 16.0 0.0 0.012 15.1 0.0 1.4 1 0 0 1 1 1 1 Replication initiation factor Methyltransf_16 PF10294.4 AIN96431.1 - 2.1e-11 43.6 0.1 4.8e-11 42.4 0.0 1.5 1 1 0 1 1 1 1 Putative methyltransferase Methyltransf_26 PF13659.1 AIN96431.1 - 1.3e-06 28.3 0.1 2.7e-06 27.3 0.1 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 AIN96431.1 - 0.001 19.5 0.1 0.0038 17.8 0.1 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 AIN96431.1 - 0.0059 16.3 0.0 0.013 15.2 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.9 AIN96431.1 - 0.006 15.9 0.4 0.1 11.9 0.3 2.2 1 1 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.8 AIN96431.1 - 0.008 15.3 0.5 0.021 13.9 0.0 1.7 2 0 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) WD40 PF00400.27 AIN96432.1 - 1.9e-09 37.0 4.6 0.67 9.9 0.0 6.0 6 0 0 6 6 6 4 WD domain, G-beta repeat PQQ PF01011.16 AIN96432.1 - 0.25 10.9 0.7 1.6 8.4 0.1 2.4 2 0 0 2 2 2 0 PQQ enzyme repeat Prenyltransf PF01255.14 AIN96433.1 - 1.7e-51 174.5 0.1 1.3e-47 161.7 0.0 2.6 3 0 0 3 3 3 2 Putative undecaprenyl diphosphate synthase Maf1 PF09174.5 AIN96433.1 - 0.035 13.9 0.0 0.061 13.1 0.0 1.4 1 0 0 1 1 1 0 Maf1 regulator DUF3086 PF11285.3 AIN96434.1 - 0.057 12.2 0.3 0.071 11.9 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3086) RNase_HII PF01351.13 AIN96436.1 - 7.2e-18 64.9 0.1 3.2e-15 56.2 0.1 2.4 1 1 0 1 1 1 1 Ribonuclease HII DNA_pol_A PF00476.15 AIN96438.1 - 3.2e-28 98.4 0.0 8.2e-28 97.0 0.0 1.6 1 1 0 1 1 1 1 DNA polymerase family A RNase_T PF00929.19 AIN96438.1 - 4.8e-15 56.2 0.0 1.8e-14 54.3 0.0 2.1 1 0 0 1 1 1 1 Exonuclease RNase_H_2 PF13482.1 AIN96438.1 - 0.03 14.1 0.0 0.11 12.3 0.0 2.0 2 0 0 2 2 2 0 RNase_H superfamily Peptidase_M32 PF02074.10 AIN96439.1 - 2.4e-124 415.6 0.0 2.7e-124 415.5 0.0 1.0 1 0 0 1 1 1 1 Carboxypeptidase Taq (M32) metallopeptidase AMA-1 PF02430.10 AIN96440.1 - 0.12 11.2 0.0 0.17 10.7 0.0 1.1 1 0 0 1 1 1 0 Apical membrane antigen 1 SURF1 PF02104.10 AIN96441.1 - 5.3e-27 95.0 0.0 1.2e-26 93.9 0.0 1.6 1 0 0 1 1 1 1 SURF1 family DUF1471 PF07338.8 AIN96441.1 - 0.028 14.0 0.0 0.06 12.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1471) F_actin_bind PF08919.5 AIN96442.1 - 0.0046 16.6 0.7 0.0081 15.8 0.5 1.6 1 1 0 1 1 1 1 F-actin binding Filament PF00038.16 AIN96442.1 - 0.017 14.6 6.5 0.018 14.5 4.5 1.1 1 0 0 1 1 1 0 Intermediate filament protein Troponin PF00992.15 AIN96442.1 - 0.018 15.0 7.0 0.022 14.8 4.8 1.2 1 0 0 1 1 1 0 Troponin Atg14 PF10186.4 AIN96442.1 - 0.024 13.5 6.4 0.034 13.0 4.5 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Vmethyltransf PF01660.12 AIN96442.1 - 0.036 12.7 0.4 0.043 12.4 0.3 1.1 1 0 0 1 1 1 0 Viral methyltransferase CCDC144C PF14915.1 AIN96442.1 - 0.048 12.5 7.0 0.065 12.1 4.9 1.2 1 0 0 1 1 1 0 CCDC144C protein coiled-coil region TPR_MLP1_2 PF07926.7 AIN96442.1 - 0.063 13.0 7.5 0.1 12.3 5.2 1.3 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein CCDC92 PF14916.1 AIN96442.1 - 0.099 12.2 8.2 0.13 11.9 0.2 2.6 2 1 0 2 2 2 0 Coiled-coil domain of unknown function DUF4472 PF14739.1 AIN96442.1 - 0.52 10.7 7.6 0.53 10.7 4.8 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4472) Herpes_UL6 PF01763.11 AIN96442.1 - 0.53 8.3 2.8 0.6 8.2 2.0 1.1 1 0 0 1 1 1 0 Herpesvirus UL6 like DUF601 PF04642.7 AIN96442.1 - 0.63 9.3 4.6 0.68 9.2 3.2 1.1 1 0 0 1 1 1 0 Protein of unknown function, DUF601 APG6 PF04111.7 AIN96442.1 - 1.4 7.9 9.2 1.6 7.7 6.3 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF972 PF06156.8 AIN96442.1 - 1.5 9.2 7.1 3.6 7.9 3.0 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF972) Mnd1 PF03962.10 AIN96442.1 - 1.8 8.1 6.5 2.3 7.8 4.5 1.2 1 0 0 1 1 1 0 Mnd1 family Kinetocho_Slk19 PF12709.2 AIN96442.1 - 2 8.5 8.0 2.2 8.3 3.1 2.2 1 1 1 2 2 2 0 Central kinetochore-associated IncA PF04156.9 AIN96442.1 - 2.5 7.6 12.0 0.4 10.2 2.1 1.8 1 1 1 2 2 2 0 IncA protein Jnk-SapK_ap_N PF09744.4 AIN96442.1 - 2.7 7.9 10.4 1.9 8.4 0.9 1.8 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 TSC22 PF01166.13 AIN96442.1 - 2.8 7.9 7.8 5.1 7.1 2.9 2.2 1 1 0 2 2 2 0 TSC-22/dip/bun family Rootletin PF15035.1 AIN96442.1 - 8.1 6.3 12.9 12 5.8 0.2 1.9 1 1 1 2 2 2 0 Ciliary rootlet component, centrosome cohesion Kinesin PF00225.18 AIN96443.1 - 3.4e-88 295.5 0.1 4.8e-88 295.0 0.1 1.1 1 0 0 1 1 1 1 Kinesin motor domain zf-TRAF PF02176.13 AIN96443.1 - 2.1e-13 50.4 46.9 1.2e-06 28.7 3.4 5.2 4 1 2 6 6 6 4 TRAF-type zinc finger PyrI_C PF02748.10 AIN96443.1 - 0.094 12.1 6.6 2.5 7.5 0.2 3.1 2 1 0 2 2 2 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain zf-Di19 PF05605.7 AIN96443.1 - 1.4 9.1 20.9 15 5.8 2.0 4.2 3 1 0 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding DAP3 PF10236.4 AIN96445.1 - 0.04 12.8 0.6 0.059 12.3 0.4 1.2 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 PhyH PF05721.8 AIN96445.1 - 0.059 13.3 0.0 10 6.0 0.0 2.7 2 1 0 2 2 2 0 Phytanoyl-CoA dioxygenase (PhyH) MASE2 PF05230.6 AIN96445.1 - 0.094 12.7 0.0 0.22 11.4 0.0 1.6 1 0 0 1 1 1 0 MASE2 domain cNMP_binding PF00027.24 AIN96446.1 - 1.6e-32 111.1 0.3 2.5e-19 68.8 0.0 2.4 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain MOZ_SAS PF01853.13 AIN96447.1 - 1.7e-20 73.0 0.0 4.2e-10 39.1 0.0 2.3 2 0 0 2 2 2 2 MOZ/SAS family TPR_12 PF13424.1 AIN96448.1 - 5.5e-14 51.8 12.8 1.3e-06 28.2 0.1 4.4 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.12 AIN96448.1 - 9.4e-07 28.2 4.1 0.4 10.7 0.0 4.7 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_10 PF13374.1 AIN96448.1 - 2.1e-05 24.3 17.9 0.026 14.4 0.1 5.9 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_6 PF13174.1 AIN96448.1 - 0.012 16.0 2.5 44 4.8 0.0 5.1 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_1 PF00515.23 AIN96448.1 - 0.028 14.0 0.3 5.4 6.7 0.0 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_16 PF13432.1 AIN96448.1 - 0.2 12.3 10.1 1.6 9.4 0.0 4.1 3 1 2 5 5 5 0 Tetratricopeptide repeat TPR_11 PF13414.1 AIN96448.1 - 0.55 9.9 5.8 13 5.4 0.0 4.1 5 1 0 5 5 5 0 TPR repeat Lipase_3 PF01764.20 AIN96450.1 - 2.2e-13 50.0 0.0 4.6e-13 48.9 0.0 1.6 1 0 0 1 1 1 1 Lipase (class 3) Lipase_3 PF01764.20 AIN96451.1 - 9.5e-15 54.4 0.0 1.9e-14 53.4 0.0 1.6 1 0 0 1 1 1 1 Lipase (class 3) UPF0227 PF05728.7 AIN96451.1 - 0.13 12.0 0.0 0.24 11.1 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) Ras PF00071.17 AIN96452.1 - 1.7e-51 173.8 0.0 2e-51 173.5 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 AIN96452.1 - 9.2e-15 55.1 0.0 1.3e-14 54.7 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 AIN96452.1 - 2.8e-12 46.2 0.0 4e-12 45.7 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 AIN96452.1 - 2.6e-08 33.2 0.0 3.4e-08 32.8 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 AIN96452.1 - 4.2e-06 26.6 0.0 6.5e-06 26.0 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.1 AIN96452.1 - 0.00014 21.8 0.1 0.00027 20.9 0.1 1.5 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 AIN96452.1 - 0.00015 21.9 0.0 0.0003 20.9 0.0 1.5 1 1 1 2 2 2 1 AAA domain DUF258 PF03193.11 AIN96452.1 - 0.00072 18.7 0.0 0.00094 18.3 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 GTP_EFTU PF00009.22 AIN96452.1 - 0.0018 17.7 0.0 0.016 14.6 0.0 1.9 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain G-alpha PF00503.15 AIN96452.1 - 0.0049 15.6 0.2 0.16 10.5 0.1 2.2 1 1 1 2 2 2 1 G-protein alpha subunit AAA_5 PF07728.9 AIN96452.1 - 0.011 15.4 0.0 0.018 14.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) NACHT PF05729.7 AIN96452.1 - 0.014 15.0 0.0 0.022 14.4 0.0 1.3 1 0 0 1 1 1 0 NACHT domain ABC_tran PF00005.22 AIN96452.1 - 0.059 13.6 0.0 0.13 12.5 0.0 1.5 1 0 0 1 1 1 0 ABC transporter AAA_25 PF13481.1 AIN96452.1 - 0.063 12.6 0.1 0.14 11.5 0.1 1.6 1 1 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 AIN96452.1 - 0.067 13.3 0.0 0.13 12.4 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_29 PF13555.1 AIN96452.1 - 0.086 12.3 0.0 0.18 11.3 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_10 PF12846.2 AIN96452.1 - 0.091 12.1 0.0 0.26 10.6 0.0 1.6 1 1 1 2 2 2 0 AAA-like domain AAA_24 PF13479.1 AIN96452.1 - 0.093 12.2 0.0 0.18 11.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.21 AIN96452.1 - 0.1 12.0 0.0 0.16 11.4 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_33 PF13671.1 AIN96452.1 - 0.11 12.3 0.2 0.37 10.6 0.1 2.1 1 1 0 1 1 1 0 AAA domain zf-C3HC4_3 PF13920.1 AIN96453.1 - 9.5e-06 25.1 8.2 2e-05 24.1 5.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 AIN96453.1 - 1.1e-05 25.1 8.7 2.1e-05 24.1 6.0 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 AIN96453.1 - 0.0058 16.6 10.0 0.011 15.7 6.9 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 AIN96453.1 - 0.014 15.2 10.4 0.032 14.0 7.2 1.7 1 0 0 1 1 1 0 Ring finger domain zf-C3HC4 PF00097.20 AIN96453.1 - 0.033 13.8 7.8 0.064 12.9 5.4 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) IncA PF04156.9 AIN96453.1 - 0.11 12.0 4.0 0.17 11.4 2.8 1.2 1 0 0 1 1 1 0 IncA protein zf-RING_4 PF14570.1 AIN96453.1 - 0.14 11.7 8.6 0.26 10.8 6.0 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain DUF1848 PF08902.6 AIN96453.1 - 0.14 11.6 0.5 0.22 11.0 0.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1848) zf-P11 PF03854.9 AIN96453.1 - 0.17 11.3 7.6 0.34 10.4 5.3 1.5 1 0 0 1 1 1 0 P-11 zinc finger Myosin_tail_1 PF01576.14 AIN96453.1 - 0.28 8.8 8.7 0.36 8.4 6.0 1.0 1 0 0 1 1 1 0 Myosin tail CALCOCO1 PF07888.6 AIN96453.1 - 0.29 9.3 4.6 0.4 8.9 3.2 1.1 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like HAUS-augmin3 PF14932.1 AIN96453.1 - 0.48 9.5 4.2 0.77 8.8 2.9 1.2 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 Atg14 PF10186.4 AIN96453.1 - 1.1 8.1 9.6 1.7 7.5 6.6 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DUF1192 PF06698.6 AIN96453.1 - 2 8.2 5.0 0.32 10.8 0.5 2.0 2 1 0 2 2 2 0 Protein of unknown function (DUF1192) DUF4200 PF13863.1 AIN96454.1 - 3e-27 95.0 21.4 3e-27 95.0 14.8 3.2 2 1 1 3 3 3 1 Domain of unknown function (DUF4200) Reo_sigmaC PF04582.7 AIN96454.1 - 0.01 15.0 2.3 0.029 13.5 0.3 2.1 2 0 0 2 2 2 0 Reovirus sigma C capsid protein Bromodomain PF00439.20 AIN96454.1 - 0.041 13.8 0.4 0.16 11.8 0.0 2.2 1 1 0 2 2 2 0 Bromodomain HTH_26 PF13443.1 AIN96454.1 - 0.26 11.4 3.7 2.2 8.5 0.4 2.7 2 0 0 2 2 2 0 Cro/C1-type HTH DNA-binding domain FMN_bind PF04205.9 AIN96454.1 - 0.42 10.8 2.2 0.45 10.7 0.1 2.1 2 0 0 2 2 2 0 FMN-binding domain KMP11 PF03037.11 AIN96454.1 - 2.3 8.8 10.4 5.6 7.6 0.1 3.1 4 0 0 4 4 4 0 Kinetoplastid membrane protein 11 M_domain PF12938.2 AIN96454.1 - 5.4 6.7 16.5 1.2 8.9 1.0 3.0 3 0 0 3 3 3 0 M domain of GW182 XhlA PF10779.4 AIN96454.1 - 8.1 6.4 12.9 1.6 8.6 0.0 3.6 2 2 2 4 4 4 0 Haemolysin XhlA Acetyltransf_1 PF00583.19 AIN96456.1 - 5.5e-14 51.9 0.1 1.1e-13 50.9 0.1 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.5 AIN96456.1 - 1.6e-07 30.9 0.0 2.7e-07 30.2 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.1 AIN96456.1 - 0.00016 21.7 0.0 0.00039 20.5 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 AIN96456.1 - 0.00074 19.4 0.2 0.0011 18.8 0.2 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 AIN96456.1 - 0.0038 17.2 0.1 0.0057 16.6 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 AIN96456.1 - 0.0099 16.0 0.0 0.016 15.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 AIN96456.1 - 0.02 14.7 1.0 0.026 14.3 0.1 1.6 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 AIN96456.1 - 0.029 14.4 0.0 0.053 13.6 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Tubulin PF00091.20 AIN96458.1 - 3.2e-66 223.2 0.0 4.3e-66 222.8 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 AIN96458.1 - 4.6e-50 168.8 0.0 7.5e-50 168.1 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.1 AIN96458.1 - 0.0072 15.8 0.0 0.016 14.7 0.0 1.6 2 0 0 2 2 2 1 Tubulin domain Nipped-B_C PF12830.2 AIN96459.1 - 6.4e-34 117.2 0.0 2.2e-33 115.4 0.0 2.0 1 1 0 1 1 1 1 Sister chromatid cohesion C-terminus AMP-binding PF00501.23 AIN96461.1 - 2.3e-58 197.5 0.3 3.2e-58 197.1 0.2 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 AIN96461.1 - 0.014 16.3 0.0 0.052 14.4 0.0 2.1 1 0 0 1 1 1 0 AMP-binding enzyme C-terminal domain FeoA PF04023.9 AIN96461.1 - 0.095 12.6 0.0 0.48 10.4 0.0 2.1 2 0 0 2 2 2 0 FeoA domain Radial_spoke PF04712.7 AIN96462.1 - 1.4e-150 502.3 11.6 3.9e-114 382.1 1.6 2.0 1 1 1 2 2 2 2 Radial spokehead-like protein Pkinase PF00069.20 AIN96463.1 - 3e-82 275.6 0.0 5.5e-82 274.8 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AIN96463.1 - 1.3e-45 155.4 0.0 2.4e-45 154.6 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase HEAT_2 PF13646.1 AIN96463.1 - 3.4e-09 36.8 0.1 3.1e-06 27.3 0.2 3.6 2 1 1 3 3 3 2 HEAT repeats Arm PF00514.18 AIN96463.1 - 6e-08 32.2 7.4 0.0014 18.3 0.0 6.5 6 0 0 6 6 6 1 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.1 AIN96463.1 - 1.8e-07 31.4 5.4 0.0095 16.4 0.1 5.6 4 1 1 5 5 4 2 HEAT-like repeat Kinase-like PF14531.1 AIN96463.1 - 3.4e-06 26.2 0.0 1.7e-05 23.9 0.0 2.0 2 0 0 2 2 2 1 Kinase-like RIO1 PF01163.17 AIN96463.1 - 0.00021 20.7 1.1 0.0026 17.1 0.4 2.3 1 1 1 2 2 2 1 RIO1 family YrbL-PhoP_reg PF10707.4 AIN96463.1 - 0.00076 18.8 0.1 0.0014 18.0 0.1 1.4 1 0 0 1 1 1 1 PhoP regulatory network protein YrbL HEAT PF02985.17 AIN96463.1 - 0.00076 19.3 3.6 2.8 8.2 0.0 5.0 5 0 0 5 5 4 2 HEAT repeat APH PF01636.18 AIN96463.1 - 0.0039 16.9 0.0 0.034 13.8 0.0 2.2 1 1 1 2 2 2 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 AIN96463.1 - 0.012 14.5 0.0 0.027 13.3 0.0 1.5 1 0 0 1 1 1 0 Seadornavirus VP7 Cnd1 PF12717.2 AIN96463.1 - 0.015 15.1 0.9 0.32 10.8 0.0 3.2 2 1 1 3 3 3 0 non-SMC mitotic condensation complex subunit 1 Kdo PF06293.9 AIN96463.1 - 0.017 14.2 0.0 0.031 13.3 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Urb2 PF10441.4 AIN96463.1 - 0.047 13.2 0.0 0.12 11.9 0.0 1.7 1 0 0 1 1 1 0 Urb2/Npa2 family Alba PF01918.16 AIN96464.1 - 2.7e-13 49.3 0.4 3.8e-13 48.8 0.3 1.2 1 0 0 1 1 1 1 Alba Rpp20 PF12328.3 AIN96464.1 - 0.016 14.8 0.9 0.02 14.5 0.6 1.3 1 1 0 1 1 1 0 Rpp20 subunit of nuclear RNase MRP and P Transketolase_C PF02780.15 AIN96464.1 - 0.12 12.2 1.8 5.7 6.8 0.2 2.1 1 1 1 2 2 2 0 Transketolase, C-terminal domain C2 PF00168.25 AIN96465.1 - 0.0086 15.8 0.1 0.041 13.7 0.0 2.1 2 0 0 2 2 2 1 C2 domain CENP-F_leu_zip PF10473.4 AIN96466.1 - 7e-09 35.6 55.9 0.0016 18.3 10.1 6.1 3 1 3 6 6 6 5 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 TMF_TATA_bd PF12325.3 AIN96466.1 - 7.9e-06 25.6 55.0 1.4e-05 24.7 1.7 5.0 2 1 3 5 5 5 3 TATA element modulatory factor 1 TATA binding LPP PF04728.8 AIN96466.1 - 0.00082 19.1 6.3 1 9.1 0.6 5.2 5 0 0 5 5 5 1 Lipoprotein leucine-zipper Filament PF00038.16 AIN96466.1 - 0.0037 16.7 56.0 0.052 13.0 12.3 5.0 1 1 2 5 5 5 2 Intermediate filament protein Myosin_tail_1 PF01576.14 AIN96466.1 - 0.0046 14.7 53.3 0.0035 15.1 15.6 3.4 2 1 1 3 3 3 1 Myosin tail Atg14 PF10186.4 AIN96466.1 - 0.0052 15.7 11.9 0.0052 15.7 8.2 3.6 2 1 2 4 4 4 3 UV radiation resistance protein and autophagy-related subunit 14 Fib_alpha PF08702.5 AIN96466.1 - 0.0052 16.9 3.1 0.0052 16.9 2.1 4.1 3 2 1 4 4 4 2 Fibrinogen alpha/beta chain family Reo_sigmaC PF04582.7 AIN96466.1 - 0.066 12.3 24.3 1.9 7.6 0.3 3.4 1 1 1 3 3 3 0 Reovirus sigma C capsid protein NPV_P10 PF05531.7 AIN96466.1 - 0.091 13.0 20.0 1.7 8.9 0.3 5.7 4 1 0 4 4 4 0 Nucleopolyhedrovirus P10 protein Pro_CA PF00484.14 AIN96466.1 - 0.097 12.6 0.0 0.097 12.6 0.0 4.0 2 1 2 4 4 4 0 Carbonic anhydrase TMF_DNA_bd PF12329.3 AIN96466.1 - 0.11 12.3 53.4 0.054 13.3 1.5 7.3 5 2 2 7 7 7 0 TATA element modulatory factor 1 DNA binding GAS PF13851.1 AIN96466.1 - 0.13 11.4 51.7 1 8.5 0.7 4.8 2 1 3 5 5 5 0 Growth-arrest specific micro-tubule binding IncA PF04156.9 AIN96466.1 - 0.27 10.7 63.0 0.93 9.0 8.5 5.1 2 1 4 6 6 6 0 IncA protein LLC1 PF14945.1 AIN96466.1 - 0.66 10.3 5.5 8.6 6.6 0.6 3.9 4 0 0 4 4 4 0 Normal lung function maintenance, Low in Lung Cancer 1 protein IFP_35_N PF07334.8 AIN96466.1 - 0.85 9.6 15.8 4.3 7.3 1.0 5.2 5 0 0 5 5 4 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus WD40_alt PF14077.1 AIN96466.1 - 1.3 8.7 8.4 3.5 7.3 1.3 4.3 5 1 0 5 5 4 0 Alternative WD40 repeat motif Surfac_D-trimer PF09006.6 AIN96466.1 - 1.6 8.4 5.2 5.8 6.7 0.1 4.2 4 0 0 4 4 4 0 Lung surfactant protein D coiled-coil trimerisation Rootletin PF15035.1 AIN96466.1 - 1.7 8.6 63.3 0.7 9.8 11.1 5.6 1 1 3 4 4 4 0 Ciliary rootlet component, centrosome cohesion THP2 PF09432.5 AIN96466.1 - 1.7 8.5 19.3 1 9.2 0.8 3.6 2 1 1 3 3 3 0 Tho complex subunit THP2 FlaC_arch PF05377.6 AIN96466.1 - 1.8 8.5 25.0 4.3 7.3 0.1 7.0 5 3 2 7 7 6 0 Flagella accessory protein C (FlaC) Seryl_tRNA_N PF02403.17 AIN96466.1 - 3.2 7.8 38.0 0.28 11.2 4.9 5.1 2 1 1 4 4 4 0 Seryl-tRNA synthetase N-terminal domain His_Phos_1 PF00300.17 AIN96467.1 - 2.7e-10 40.5 0.0 6.9e-10 39.2 0.0 1.9 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Sec63 PF02889.11 AIN96468.1 - 4.9e-153 508.9 3.0 1.7e-89 300.1 0.9 2.8 3 0 0 3 3 3 2 Sec63 Brl domain DEAD PF00270.24 AIN96468.1 - 1.6e-54 183.9 0.1 3.3e-29 101.5 0.1 2.9 2 0 0 2 2 2 2 DEAD/DEAH box helicase ResIII PF04851.10 AIN96468.1 - 1.1e-22 80.7 0.0 2e-13 50.5 0.0 2.4 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit Helicase_C PF00271.26 AIN96468.1 - 2.3e-16 59.4 0.0 1.3e-07 31.3 0.0 2.9 2 0 0 2 2 2 2 Helicase conserved C-terminal domain SNF2_N PF00176.18 AIN96468.1 - 3.3e-08 32.6 0.4 1.6e-05 23.9 0.1 2.5 2 0 0 2 2 2 2 SNF2 family N-terminal domain AAA_10 PF12846.2 AIN96468.1 - 7.1e-06 25.6 0.1 0.18 11.2 0.0 4.4 4 1 0 5 5 5 1 AAA-like domain AAA_19 PF13245.1 AIN96468.1 - 8.5e-06 25.4 0.0 0.084 12.6 0.0 2.8 2 0 0 2 2 2 2 Part of AAA domain AAA_22 PF13401.1 AIN96468.1 - 4e-05 23.7 0.6 0.033 14.3 0.0 3.7 3 2 0 3 3 2 1 AAA domain PhoH PF02562.11 AIN96468.1 - 5e-05 22.6 0.1 0.034 13.3 0.0 2.4 2 0 0 2 2 2 2 PhoH-like protein T2SE PF00437.15 AIN96468.1 - 0.00018 20.5 0.0 0.61 8.9 0.0 2.9 3 0 0 3 3 3 2 Type II/IV secretion system protein DUF2075 PF09848.4 AIN96468.1 - 0.0038 16.2 0.0 0.013 14.4 0.0 1.9 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) IstB_IS21 PF01695.12 AIN96468.1 - 0.015 14.7 0.1 8.3 5.7 0.0 3.1 3 0 0 3 3 3 0 IstB-like ATP binding protein UvrD-helicase PF00580.16 AIN96468.1 - 0.047 12.9 0.7 2.2 7.5 0.0 2.6 3 0 0 3 3 3 0 UvrD/REP helicase N-terminal domain AAA PF00004.24 AIN96468.1 - 0.078 13.1 1.3 6.1 7.0 0.2 3.8 3 2 0 3 3 2 0 ATPase family associated with various cellular activities (AAA) DUF1014 PF06244.7 AIN96470.1 - 1.1e-14 54.6 15.8 9.7e-14 51.6 10.3 2.6 1 1 0 1 1 1 1 Protein of unknown function (DUF1014) HMG_box PF00505.14 AIN96470.1 - 0.07 13.4 0.5 0.07 13.4 0.3 3.1 2 1 1 3 3 3 0 HMG (high mobility group) box DUF3435 PF11917.3 AIN96470.1 - 0.26 9.9 11.6 0.38 9.4 8.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3435) DUF3464 PF11947.3 AIN96470.1 - 9.8 5.6 8.6 20 4.5 6.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3464) FANCI_HD1 PF14679.1 AIN96471.1 - 0.19 11.4 1.6 8 6.2 0.0 3.1 3 0 0 3 3 3 0 FANCI helical domain 1 DUF179 PF02622.10 AIN96473.1 - 1.3e-26 93.1 0.0 2.5e-26 92.2 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized ACR, COG1678 Ribosomal_L18e PF00828.14 AIN96474.1 - 9.6e-20 71.2 0.2 9.6e-20 71.2 0.2 1.5 2 0 0 2 2 2 1 Ribosomal protein L18e/L15 Ribosomal_L7Ae PF01248.21 AIN96475.1 - 2e-22 78.4 1.0 2.8e-22 78.0 0.7 1.2 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family ETF PF01012.16 AIN96475.1 - 0.024 14.3 0.3 0.035 13.8 0.2 1.2 1 0 0 1 1 1 0 Electron transfer flavoprotein domain Phage_NinH PF06322.6 AIN96475.1 - 0.065 12.8 0.5 8.1 6.1 0.0 2.3 2 0 0 2 2 2 0 Phage NinH protein DUF972 PF06156.8 AIN96476.1 - 0.43 10.9 1.4 2.8 8.3 0.2 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF972) DUF607 PF04678.8 AIN96478.1 - 2.3e-14 53.7 0.3 3.4e-14 53.1 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function, DUF607 DUF1192 PF06698.6 AIN96478.1 - 0.045 13.5 0.1 0.045 13.5 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) Acetyltransf_1 PF00583.19 AIN96479.1 - 3.7e-05 23.6 0.1 7.7e-05 22.6 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 AIN96479.1 - 0.01 16.0 0.0 0.022 14.9 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain IBN_N PF03810.14 AIN96482.1 - 0.00065 19.5 0.0 0.17 11.8 0.0 3.6 3 1 0 3 3 3 1 Importin-beta N-terminal domain HEAT PF02985.17 AIN96482.1 - 0.0034 17.3 0.2 0.037 14.1 0.2 3.0 1 0 0 1 1 1 1 HEAT repeat Cse1 PF08506.5 AIN96482.1 - 0.0065 15.0 0.0 0.016 13.7 0.0 1.6 1 0 0 1 1 1 1 Cse1 HEAT_2 PF13646.1 AIN96482.1 - 0.21 11.8 0.0 0.21 11.8 0.0 4.8 5 0 0 5 5 5 0 HEAT repeats DUF3295 PF11702.3 AIN96482.1 - 6.7 5.5 6.9 12 4.7 4.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3295) SDA1 PF05285.7 AIN96482.1 - 8.6 5.5 17.7 13 4.9 12.2 1.1 1 0 0 1 1 1 0 SDA1 zf-DHHC PF01529.15 AIN96483.1 - 1.9e-39 134.8 0.0 1.9e-39 134.8 0.0 1.7 2 0 0 2 2 2 1 DHHC palmitoyltransferase BTV_NS2 PF04514.7 AIN96483.1 - 0.12 11.1 5.5 0.19 10.5 3.8 1.2 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 U-box PF04564.10 AIN96484.1 - 4.8e-05 23.2 0.0 0.00011 22.1 0.0 1.5 1 0 0 1 1 1 1 U-box domain Lectin_leg-like PF03388.8 AIN96485.1 - 6.1e-43 146.5 0.0 8.6e-43 146.0 0.0 1.1 1 0 0 1 1 1 1 Legume-like lectin family Peptidase_M24 PF00557.19 AIN96486.1 - 1.3e-22 80.4 0.4 1.3e-22 80.4 0.3 2.2 2 1 1 3 3 3 1 Metallopeptidase family M24 PSP1 PF04468.7 AIN96487.1 - 5.7e-25 87.1 0.0 1.3e-24 85.9 0.0 1.6 1 0 0 1 1 1 1 PSP1 C-terminal conserved region Kinesin PF00225.18 AIN96488.1 - 3.9e-34 117.8 0.0 5e-10 38.5 0.0 5.1 4 1 0 4 4 4 4 Kinesin motor domain ArfGap PF01412.13 AIN96489.1 - 6.5e-29 100.0 0.1 1.1e-28 99.2 0.0 1.3 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf ADH_zinc_N PF00107.21 AIN96490.1 - 2.6e-17 62.6 0.0 4.9e-17 61.6 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 AIN96490.1 - 5.6e-13 48.6 0.1 3.1e-12 46.1 0.0 2.1 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ubiquitin PF00240.18 AIN96491.1 - 8.8e-10 37.8 0.0 1.6e-09 36.9 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 AIN96491.1 - 2.3e-05 23.9 0.0 5.8e-05 22.7 0.0 1.7 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 AIN96491.1 - 0.0019 18.3 0.0 0.0066 16.6 0.0 1.9 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain Rad60-SLD_2 PF13881.1 AIN96491.1 - 0.0042 16.9 0.0 0.017 15.0 0.0 2.0 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 AIN96491.1 - 0.092 13.0 0.0 0.23 11.7 0.0 1.6 1 0 0 1 1 1 0 Ubiquitin-like domain Anoctamin PF04547.7 AIN96492.1 - 9.3e-87 291.5 0.0 1.2e-86 291.1 0.0 1.1 1 0 0 1 1 1 1 Calcium-activated chloride channel IPP-2 PF04979.9 AIN96493.1 - 0.066 13.4 2.6 0.1 12.8 1.8 1.4 1 0 0 1 1 1 0 Protein phosphatase inhibitor 2 (IPP-2) C2 PF00168.25 AIN96494.1 - 1.6e-16 59.8 0.0 4.6e-16 58.4 0.0 1.8 1 0 0 1 1 1 1 C2 domain YbjQ_1 PF01906.12 AIN96494.1 - 5e-05 23.6 0.0 0.42 11.0 0.0 4.0 4 0 0 4 4 4 2 Putative heavy-metal-binding DSPc PF00782.15 AIN96495.1 - 3.1e-09 36.4 0.0 6e-09 35.5 0.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Pkinase PF00069.20 AIN96496.1 - 1.4e-41 142.3 0.0 5.6e-33 114.1 0.0 3.2 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 AIN96496.1 - 9.3e-17 60.9 0.0 1.9e-15 56.6 0.0 2.7 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 AIN96496.1 - 0.0014 17.6 0.0 0.0037 16.2 0.0 1.7 1 0 0 1 1 1 1 Kinase-like DUF2392 PF10288.4 AIN96497.1 - 1.5e-05 25.2 0.0 3.8e-05 23.9 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF2392) MSP1_C PF07462.6 AIN96497.1 - 0.4 9.0 0.2 0.85 7.9 0.1 1.5 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus Complex1_LYR_2 PF13233.1 AIN96500.1 - 4.6e-05 23.8 0.0 9.4e-05 22.8 0.0 1.5 1 1 0 1 1 1 1 Complex1_LYR-like IncA PF04156.9 AIN96501.1 - 0.058 12.9 7.0 0.96 9.0 0.7 2.9 2 0 0 2 2 2 0 IncA protein AraC_N PF06719.8 AIN96503.1 - 0.051 12.8 1.1 0.078 12.2 0.1 1.8 2 0 0 2 2 2 0 AraC-type transcriptional regulator N-terminus Pro-rich PF15240.1 AIN96504.1 - 0.0014 18.7 4.6 0.0014 18.7 3.2 1.5 2 0 0 2 2 2 1 Proline-rich Peptidase_M16 PF00675.15 AIN96505.1 - 2e-08 34.0 0.1 2.3e-07 30.6 0.0 2.4 1 1 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 AIN96505.1 - 0.00036 20.2 0.0 0.0018 17.9 0.0 2.2 2 1 0 2 2 2 1 Peptidase M16 inactive domain Flagellin_IN PF07196.8 AIN96505.1 - 0.092 12.7 0.1 0.23 11.4 0.1 1.6 1 0 0 1 1 1 0 Flagellin hook IN motif Spt20 PF12090.3 AIN96506.1 - 0.0044 16.3 0.9 0.0044 16.3 0.7 2.6 3 0 0 3 3 3 1 Spt20 family Nop14 PF04147.7 AIN96506.1 - 0.051 11.4 30.5 0.089 10.7 21.1 1.3 1 0 0 1 1 1 0 Nop14-like family LRR_6 PF13516.1 AIN96509.1 - 1.2e-07 31.0 1.6 0.024 14.6 0.0 4.0 3 0 0 3 3 3 2 Leucine Rich repeat LRR_4 PF12799.2 AIN96509.1 - 5.5e-07 29.0 3.4 2e-06 27.2 2.4 2.0 1 0 0 1 1 1 1 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 AIN96509.1 - 0.00011 21.7 4.9 0.086 12.9 0.5 3.2 2 0 0 2 2 2 2 Leucine Rich Repeat LRR_8 PF13855.1 AIN96509.1 - 0.00074 19.2 1.7 0.00074 19.2 1.2 2.3 1 1 1 2 2 2 2 Leucine rich repeat LRR_7 PF13504.1 AIN96509.1 - 0.017 15.2 4.0 1.3 9.5 0.1 3.5 3 0 0 3 3 3 0 Leucine rich repeat Ax_dynein_light PF10211.4 AIN96510.1 - 4e-06 26.7 4.9 4e-06 26.7 3.4 2.3 2 0 0 2 2 2 1 Axonemal dynein light chain Spc7 PF08317.6 AIN96510.1 - 0.13 10.8 2.6 0.25 9.9 1.8 1.4 1 0 0 1 1 1 0 Spc7 kinetochore protein V_ATPase_I PF01496.14 AIN96510.1 - 2.5 5.8 1.7 4.2 5.1 1.2 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family APG6 PF04111.7 AIN96510.1 - 8.6 5.2 12.2 0.68 8.9 3.2 2.3 2 0 0 2 2 2 0 Autophagy protein Apg6 Glyco_transf_25 PF01755.12 AIN96511.1 - 1.6e-18 67.1 0.0 2.3e-17 63.3 0.0 2.1 1 1 0 1 1 1 1 Glycosyltransferase family 25 (LPS biosynthesis protein) TRM PF02005.11 AIN96512.1 - 1.2e-92 310.8 0.0 3.3e-44 151.3 0.0 3.1 3 0 0 3 3 3 3 N2,N2-dimethylguanosine tRNA methyltransferase Actin PF00022.14 AIN96513.1 - 2.5e-109 365.3 0.0 2.1e-108 362.2 0.0 1.9 1 1 0 1 1 1 1 Actin MreB_Mbl PF06723.8 AIN96513.1 - 0.17 10.4 0.0 9.1 4.7 0.0 2.1 2 0 0 2 2 2 0 MreB/Mbl protein AAA PF00004.24 AIN96514.1 - 1.2e-37 129.0 0.0 2.1e-37 128.2 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 AIN96514.1 - 6.5e-06 26.3 0.8 0.00023 21.2 0.1 2.9 2 1 0 2 2 2 1 AAA domain RuvB_N PF05496.7 AIN96514.1 - 1.1e-05 24.6 0.0 1.6e-05 24.0 0.0 1.2 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus Vps4_C PF09336.5 AIN96514.1 - 2.3e-05 24.1 0.0 5.7e-05 22.9 0.0 1.6 1 0 0 1 1 1 1 Vps4 C terminal oligomerisation domain AAA_25 PF13481.1 AIN96514.1 - 0.00018 21.0 0.3 0.14 11.5 0.2 2.4 1 1 1 2 2 2 2 AAA domain AAA_19 PF13245.1 AIN96514.1 - 0.00054 19.6 0.2 0.0056 16.4 0.0 2.4 2 0 0 2 2 2 1 Part of AAA domain TIP49 PF06068.8 AIN96514.1 - 0.00068 18.4 0.0 0.0011 17.7 0.0 1.2 1 0 0 1 1 1 1 TIP49 C-terminus IstB_IS21 PF01695.12 AIN96514.1 - 0.0014 18.0 0.0 0.0029 17.0 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_16 PF13191.1 AIN96514.1 - 0.0017 18.3 0.1 0.009 16.0 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain AAA_18 PF13238.1 AIN96514.1 - 0.0033 17.7 0.0 0.0096 16.2 0.0 1.9 2 0 0 2 2 1 1 AAA domain AAA_17 PF13207.1 AIN96514.1 - 0.0033 18.2 0.0 0.0073 17.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.9 AIN96514.1 - 0.0081 15.8 0.1 0.018 14.7 0.0 1.7 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_33 PF13671.1 AIN96514.1 - 0.009 15.8 0.0 0.019 14.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_2 PF07724.9 AIN96514.1 - 0.01 15.7 0.0 0.018 14.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) Mg_chelatase PF01078.16 AIN96514.1 - 0.012 14.7 0.0 0.021 14.0 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI KaiC PF06745.8 AIN96514.1 - 0.016 14.3 0.1 0.63 9.1 0.0 2.2 1 1 1 2 2 2 0 KaiC AAA_24 PF13479.1 AIN96514.1 - 0.017 14.7 0.0 0.032 13.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 AIN96514.1 - 0.026 14.7 0.0 0.052 13.7 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_14 PF13173.1 AIN96514.1 - 0.027 14.3 0.0 0.048 13.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.1 AIN96514.1 - 0.027 14.4 0.0 0.11 12.4 0.0 2.0 2 0 0 2 2 2 0 AAA domain PhoH PF02562.11 AIN96514.1 - 0.028 13.6 0.1 0.1 11.8 0.0 1.8 2 0 0 2 2 2 0 PhoH-like protein LisH PF08513.6 AIN96514.1 - 0.057 13.2 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 LisH Mesothelin PF06060.7 AIN96514.1 - 0.068 11.2 0.1 0.11 10.5 0.0 1.2 1 0 0 1 1 1 0 Pre-pro-megakaryocyte potentiating factor precursor (Mesothelin) A_deaminase PF00962.17 AIN96516.1 - 1.5e-78 264.0 0.0 1e-73 248.1 0.0 2.6 2 0 0 2 2 2 2 Adenosine/AMP deaminase BRCA2 PF00634.13 AIN96518.1 - 0.04 13.2 0.3 0.083 12.1 0.2 1.5 1 0 0 1 1 1 0 BRCA2 repeat COX7a PF02238.10 AIN96518.1 - 0.12 12.0 0.0 0.28 10.9 0.0 1.5 1 0 0 1 1 1 0 Cytochrome c oxidase subunit VIIa NKAIN PF05640.9 AIN96519.1 - 0.059 12.3 1.1 0.12 11.3 0.1 1.9 2 0 0 2 2 2 0 Na,K-Atpase Interacting protein CAP59_mtransfer PF11735.3 AIN96520.1 - 3.2e-78 262.3 0.0 1.1e-76 257.2 0.0 2.3 2 0 0 2 2 2 2 Cryptococcal mannosyltransferase 1 Peptidase_S8 PF00082.17 AIN96522.1 - 8.5e-24 84.1 1.7 5e-22 78.3 0.2 2.6 2 0 0 2 2 2 2 Subtilase family Dpy-30 PF05186.8 AIN96523.1 - 1.8e-07 30.4 0.4 4.2e-07 29.3 0.3 1.6 1 0 0 1 1 1 1 Dpy-30 motif FAD_binding_6 PF00970.19 AIN96524.1 - 1.9e-28 98.4 0.0 2.8e-28 97.9 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.16 AIN96524.1 - 2.3e-27 95.7 0.0 3.8e-26 91.7 0.0 2.6 2 1 1 3 3 3 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.7 AIN96524.1 - 0.0014 18.5 0.0 0.035 14.0 0.0 2.4 3 0 0 3 3 3 1 Ferric reductase NAD binding domain AAA PF00004.24 AIN96525.1 - 1.4e-42 144.9 0.0 2.4e-42 144.2 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 AIN96525.1 - 2e-06 27.9 0.2 0.00032 20.8 0.1 2.4 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.9 AIN96525.1 - 2.6e-06 27.1 0.1 8.9e-06 25.4 0.1 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 AIN96525.1 - 2.8e-06 27.3 0.0 5.7e-06 26.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.1 AIN96525.1 - 3.5e-05 23.8 0.1 0.0014 18.6 0.0 2.0 1 1 1 2 2 2 1 AAA ATPase domain AAA_17 PF13207.1 AIN96525.1 - 0.0005 20.8 0.2 0.0022 18.8 0.0 2.1 2 1 0 2 2 2 1 AAA domain DUF815 PF05673.8 AIN96525.1 - 0.00053 18.9 0.0 0.00083 18.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) RuvB_N PF05496.7 AIN96525.1 - 0.0015 17.5 0.0 0.0027 16.7 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 AIN96525.1 - 0.0043 16.7 0.4 0.0087 15.7 0.3 1.4 1 0 0 1 1 1 1 Part of AAA domain AAA_18 PF13238.1 AIN96525.1 - 0.0052 17.1 0.1 0.011 16.0 0.1 1.7 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 AIN96525.1 - 0.0057 16.5 0.0 0.012 15.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.1 AIN96525.1 - 0.0065 16.3 0.0 0.012 15.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_3 PF07726.6 AIN96525.1 - 0.0079 15.7 0.0 0.019 14.5 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.1 AIN96525.1 - 0.017 15.1 0.2 0.039 13.9 0.0 1.7 2 0 0 2 2 1 0 AAA domain IstB_IS21 PF01695.12 AIN96525.1 - 0.021 14.2 0.1 0.042 13.2 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein RNA_helicase PF00910.17 AIN96525.1 - 0.022 14.9 0.0 0.059 13.5 0.0 1.8 2 0 0 2 2 1 0 RNA helicase KaiC PF06745.8 AIN96525.1 - 0.029 13.4 0.3 0.26 10.3 0.1 2.1 1 1 1 2 2 2 0 KaiC NACHT PF05729.7 AIN96525.1 - 0.031 13.9 0.1 0.69 9.5 0.1 2.3 1 1 1 2 2 2 0 NACHT domain AAA_25 PF13481.1 AIN96525.1 - 0.035 13.5 0.6 1.9 7.8 0.1 2.4 1 1 1 2 2 2 0 AAA domain Zeta_toxin PF06414.7 AIN96525.1 - 0.038 13.0 0.0 0.067 12.2 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin NB-ARC PF00931.17 AIN96525.1 - 0.047 12.5 0.0 0.093 11.5 0.0 1.6 1 0 0 1 1 1 0 NB-ARC domain DUF2075 PF09848.4 AIN96525.1 - 0.056 12.4 0.0 0.098 11.6 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_24 PF13479.1 AIN96525.1 - 0.08 12.5 1.3 0.33 10.5 0.1 2.5 4 0 0 4 4 3 0 AAA domain TIP49 PF06068.8 AIN96525.1 - 0.082 11.6 0.0 0.15 10.7 0.0 1.3 1 0 0 1 1 1 0 TIP49 C-terminus Mg_chelatase PF01078.16 AIN96525.1 - 0.093 11.8 0.0 0.18 10.9 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI tRNA-synt_1 PF00133.17 AIN96526.1 - 4.3e-30 104.2 0.0 7e-11 40.8 0.0 4.0 3 1 0 3 3 3 3 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.6 AIN96526.1 - 4.6e-22 78.2 0.0 4.5e-11 42.0 0.0 3.1 3 0 0 3 3 3 2 tRNA synthetases class I (M) Anticodon_1 PF08264.8 AIN96526.1 - 9.7e-12 44.9 1.1 1.9e-11 43.9 0.2 1.9 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.14 AIN96526.1 - 3.1e-07 29.8 0.0 6.8e-07 28.7 0.0 1.5 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain Methyltransf_23 PF13489.1 AIN96527.1 - 0.022 14.5 0.6 0.062 13.0 0.1 2.0 2 0 0 2 2 2 0 Methyltransferase domain Clathrin_H_link PF13838.1 AIN96527.1 - 1.7 8.5 7.2 2.6 7.9 0.3 2.9 2 0 0 2 2 2 0 Clathrin-H-link RNA_pol_N PF01194.12 AIN96528.1 - 7.7e-26 89.8 1.1 9.6e-26 89.5 0.7 1.1 1 0 0 1 1 1 1 RNA polymerases N / 8 kDa subunit DUF155 PF02582.9 AIN96529.1 - 1.6e-37 129.0 0.0 2.4e-37 128.5 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 DUF780 PF05611.6 AIN96529.1 - 0.16 12.6 13.7 0.061 14.0 5.5 2.5 2 0 0 2 2 2 0 Caenorhabditis elegans protein of unknown function (DUF780) DUF1664 PF07889.7 AIN96529.1 - 0.17 11.6 0.0 0.36 10.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Abhydrolase_6 PF12697.2 AIN96530.1 - 6.3e-22 78.5 2.6 9.8e-21 74.6 1.8 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 AIN96530.1 - 2.5e-09 37.0 0.1 1.8e-08 34.2 0.1 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 AIN96530.1 - 5.7e-08 32.6 0.4 0.0013 18.3 0.0 2.8 2 1 0 2 2 2 2 alpha/beta hydrolase fold LCAT PF02450.10 AIN96530.1 - 0.0082 15.1 0.0 0.013 14.4 0.0 1.2 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase Esterase PF00756.15 AIN96530.1 - 0.0094 15.3 0.0 0.017 14.5 0.0 1.4 1 0 0 1 1 1 1 Putative esterase Abhydrolase_4 PF08386.5 AIN96530.1 - 0.047 13.5 0.0 0.14 12.0 0.0 1.8 1 0 0 1 1 1 0 TAP-like protein Abhydro_lipase PF04083.11 AIN96530.1 - 0.057 12.7 0.1 0.16 11.3 0.0 1.7 2 0 0 2 2 2 0 Partial alpha/beta-hydrolase lipase region PGAP1 PF07819.8 AIN96530.1 - 0.089 12.3 0.0 0.25 10.8 0.0 1.7 2 0 0 2 2 2 0 PGAP1-like protein Endonuc-BglII PF09195.6 AIN96531.1 - 0.034 13.6 0.0 0.058 12.8 0.0 1.3 1 0 0 1 1 1 0 Restriction endonuclease BglII EF-hand_7 PF13499.1 AIN96532.1 - 2.1e-15 56.5 0.1 4.8e-07 29.8 0.1 2.5 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.27 AIN96532.1 - 1.3e-14 52.3 1.9 1.4e-07 30.3 0.0 3.8 5 0 0 5 5 5 2 EF hand EF-hand_8 PF13833.1 AIN96532.1 - 3.7e-12 45.6 0.8 3e-05 23.5 0.0 3.7 3 1 1 4 4 4 3 EF-hand domain pair EF-hand_6 PF13405.1 AIN96532.1 - 1.9e-09 36.5 0.1 1.6e-05 24.3 0.0 3.5 2 1 0 3 3 3 2 EF-hand domain EF-hand_5 PF13202.1 AIN96532.1 - 1.2e-07 30.6 0.1 6.3e-05 22.1 0.0 3.3 2 2 1 3 3 3 2 EF hand EF-hand_9 PF14658.1 AIN96532.1 - 0.0057 16.5 0.0 4.6 7.2 0.0 2.5 2 0 0 2 2 2 2 EF-hand domain MAM33 PF02330.11 AIN96533.1 - 0.00015 21.6 0.0 0.00027 20.7 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial glycoprotein Vac7 PF12751.2 AIN96533.1 - 0.46 9.2 4.4 0.072 11.9 0.4 1.5 2 0 0 2 2 2 0 Vacuolar segregation subunit 7 Tctex-1 PF03645.8 AIN96534.1 - 1e-25 89.5 0.0 1.2e-25 89.2 0.0 1.1 1 0 0 1 1 1 1 Tctex-1 family Adenylsucc_synt PF00709.16 AIN96535.1 - 7.9e-124 413.5 0.0 9.6e-124 413.2 0.0 1.1 1 0 0 1 1 1 1 Adenylosuccinate synthetase Ribosomal_L27 PF01016.14 AIN96536.1 - 0.038 13.7 0.0 0.14 11.9 0.0 1.8 2 0 0 2 2 2 0 Ribosomal L27 protein Nucleoside_tran PF01733.13 AIN96537.1 - 1.5e-28 99.8 8.5 2.7e-26 92.4 5.9 2.4 1 1 0 1 1 1 1 Nucleoside transporter TCO89 PF10452.4 AIN96537.1 - 0.42 9.4 1.8 0.55 9.0 1.2 1.0 1 0 0 1 1 1 0 TORC1 subunit TCO89 Ribosomal_S4e PF00900.15 AIN96538.1 - 1.6e-25 88.5 0.1 2.7e-25 87.8 0.0 1.4 1 0 0 1 1 1 1 Ribosomal family S4e RS4NT PF08071.7 AIN96538.1 - 1e-18 66.8 3.4 2.3e-18 65.7 2.4 1.7 1 0 0 1 1 1 1 RS4NT (NUC023) domain KOW PF00467.24 AIN96538.1 - 1.1e-06 28.1 0.4 3.5e-06 26.5 0.3 1.9 1 0 0 1 1 1 1 KOW motif S4 PF01479.20 AIN96538.1 - 1.3e-06 27.7 0.1 6.6e-06 25.4 0.0 2.2 3 0 0 3 3 3 1 S4 domain TPK_catalytic PF04263.11 AIN96539.1 - 2e-09 37.0 0.1 0.00067 19.2 0.0 3.8 3 1 1 4 4 4 3 Thiamin pyrophosphokinase, catalytic domain TPK_B1_binding PF04265.9 AIN96539.1 - 1.2e-08 34.4 0.0 4.6e-08 32.6 0.0 1.8 2 0 0 2 2 2 1 Thiamin pyrophosphokinase, vitamin B1 binding domain PARP PF00644.15 AIN96539.1 - 0.12 11.7 0.0 0.2 11.0 0.0 1.3 1 0 0 1 1 1 0 Poly(ADP-ribose) polymerase catalytic domain Herpes_LMP1 PF05297.6 AIN96540.1 - 0.007 15.3 0.0 0.0082 15.1 0.0 1.1 1 0 0 1 1 1 1 Herpesvirus latent membrane protein 1 (LMP1) RDD PF06271.7 AIN96540.1 - 0.023 14.6 0.0 0.027 14.3 0.0 1.1 1 0 0 1 1 1 0 RDD family BatA PF07584.6 AIN96540.1 - 0.034 14.3 0.0 0.052 13.7 0.0 1.3 1 0 0 1 1 1 0 Aerotolerance regulator N-terminal PIG-P PF08510.7 AIN96540.1 - 0.061 12.9 0.0 0.072 12.7 0.0 1.2 1 0 0 1 1 1 0 PIG-P Neurensin PF14927.1 AIN96541.1 - 0.04 13.2 0.0 0.065 12.6 0.0 1.3 1 0 0 1 1 1 0 Neurensin NicO PF03824.11 AIN96541.1 - 0.071 12.4 0.0 0.1 11.8 0.0 1.2 1 0 0 1 1 1 0 High-affinity nickel-transport protein Endonuclease_NS PF01223.18 AIN96542.1 - 2e-16 60.2 0.1 3.5e-16 59.4 0.1 1.4 1 0 0 1 1 1 1 DNA/RNA non-specific endonuclease ATP_bind_1 PF03029.12 AIN96543.1 - 1.2e-62 211.6 0.0 2.7e-62 210.4 0.0 1.5 1 1 0 1 1 1 1 Conserved hypothetical ATP binding protein GTP_EFTU PF00009.22 AIN96543.1 - 3.7e-05 23.2 0.0 0.0014 18.1 0.0 2.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain SRP54 PF00448.17 AIN96543.1 - 4.9e-05 22.8 0.0 0.0012 18.2 0.0 2.3 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain CbiA PF01656.18 AIN96543.1 - 0.00015 21.2 0.0 0.00023 20.6 0.0 1.4 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain MMR_HSR1 PF01926.18 AIN96543.1 - 0.0003 20.7 0.1 0.00056 19.8 0.1 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.1 AIN96543.1 - 0.00044 20.2 0.0 0.0014 18.6 0.0 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_19 PF13245.1 AIN96543.1 - 0.0013 18.4 0.0 0.0045 16.7 0.0 1.9 1 0 0 1 1 1 1 Part of AAA domain MobB PF03205.9 AIN96543.1 - 0.0014 18.3 0.0 0.0025 17.5 0.0 1.5 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_24 PF13479.1 AIN96543.1 - 0.0016 18.0 0.0 0.0026 17.3 0.0 1.3 1 0 0 1 1 1 1 AAA domain Miro PF08477.8 AIN96543.1 - 0.0023 18.4 0.0 0.11 13.0 0.0 2.3 2 0 0 2 2 2 1 Miro-like protein AAA_22 PF13401.1 AIN96543.1 - 0.0024 17.9 0.0 0.0059 16.7 0.0 1.7 2 0 0 2 2 1 1 AAA domain Arf PF00025.16 AIN96543.1 - 0.0025 17.0 0.0 0.2 10.8 0.0 2.3 2 0 0 2 2 2 1 ADP-ribosylation factor family AAA_33 PF13671.1 AIN96543.1 - 0.0038 17.1 0.0 0.0057 16.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.1 AIN96543.1 - 0.0046 16.5 0.2 0.012 15.1 0.0 1.7 2 0 0 2 2 2 1 AAA domain cobW PF02492.14 AIN96543.1 - 0.0049 16.3 0.4 0.23 10.8 0.0 2.5 2 1 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain ArgK PF03308.11 AIN96543.1 - 0.006 15.4 0.2 0.28 9.9 0.0 3.0 1 1 0 2 2 2 1 ArgK protein NACHT PF05729.7 AIN96543.1 - 0.007 16.0 0.0 0.017 14.7 0.0 1.7 1 0 0 1 1 1 1 NACHT domain NB-ARC PF00931.17 AIN96543.1 - 0.013 14.3 0.0 0.022 13.6 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain AAA_17 PF13207.1 AIN96543.1 - 0.014 16.2 0.1 0.028 15.2 0.1 1.6 1 1 0 1 1 1 0 AAA domain DUF258 PF03193.11 AIN96543.1 - 0.016 14.3 0.0 0.32 10.1 0.1 2.5 2 1 0 2 2 2 0 Protein of unknown function, DUF258 Zeta_toxin PF06414.7 AIN96543.1 - 0.017 14.2 0.0 0.03 13.4 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin SRPRB PF09439.5 AIN96543.1 - 0.018 14.2 0.0 0.62 9.2 0.0 2.2 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit PduV-EutP PF10662.4 AIN96543.1 - 0.041 13.3 0.0 0.29 10.5 0.0 2.2 2 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Ras PF00071.17 AIN96543.1 - 0.049 13.0 0.3 1.9 7.8 0.0 2.5 3 1 0 3 3 2 0 Ras family AAA PF00004.24 AIN96543.1 - 0.064 13.4 0.0 0.14 12.3 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 AIN96543.1 - 0.1 12.3 0.0 0.18 11.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) DUF2075 PF09848.4 AIN96543.1 - 0.12 11.3 0.0 0.15 10.9 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_18 PF13238.1 AIN96543.1 - 0.13 12.5 0.0 0.2 11.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain G-alpha PF00503.15 AIN96543.1 - 0.13 10.8 0.0 4.1 5.9 0.0 2.1 2 0 0 2 2 2 0 G-protein alpha subunit APS_kinase PF01583.15 AIN96543.1 - 0.13 11.8 0.0 0.33 10.6 0.0 1.7 2 0 0 2 2 1 0 Adenylylsulphate kinase NTPase_1 PF03266.10 AIN96543.1 - 0.14 11.8 0.0 0.43 10.2 0.0 1.8 2 0 0 2 2 2 0 NTPase Septin PF00735.13 AIN96543.1 - 0.14 11.1 0.1 0.52 9.2 0.1 2.1 1 1 0 1 1 1 0 Septin AAA_14 PF13173.1 AIN96543.1 - 0.14 12.0 0.0 0.25 11.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain Complex1_LYR PF05347.10 AIN96545.1 - 6.2e-08 32.3 0.2 1.5e-07 31.0 0.1 1.7 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 AIN96545.1 - 6.4e-06 26.2 0.3 1.4e-05 25.2 0.2 1.7 1 1 0 1 1 1 1 Complex1_LYR-like Shisa PF13908.1 AIN96546.1 - 0.00059 20.0 0.9 0.0011 19.2 0.6 1.4 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator DUF3733 PF12534.3 AIN96546.1 - 0.0086 15.3 0.1 0.0086 15.3 0.1 1.8 2 0 0 2 2 2 1 Leucine-rich repeat containing protein 8 DUF3357 PF11837.3 AIN96546.1 - 0.011 15.5 0.0 0.45 10.3 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3357) TMEM52 PF14979.1 AIN96546.1 - 0.057 13.3 0.1 0.1 12.4 0.0 1.3 1 0 0 1 1 1 0 Transmembrane 52 FAM163 PF15069.1 AIN96546.1 - 0.11 13.0 0.0 0.21 12.1 0.0 1.5 1 0 0 1 1 1 0 FAM163 family zf-LITAF-like PF10601.4 AIN96546.1 - 0.14 12.0 1.4 0.36 10.7 0.9 1.7 1 0 0 1 1 1 0 LITAF-like zinc ribbon domain DUF1475 PF07343.6 AIN96547.1 - 0.023 14.0 0.1 0.035 13.4 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1475) DUF4492 PF14899.1 AIN96547.1 - 0.026 14.0 3.0 0.05 13.0 2.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4492) SCIMP PF15050.1 AIN96547.1 - 0.13 12.1 0.2 0.93 9.3 0.1 2.2 2 0 0 2 2 2 0 SCIMP protein DUF3753 PF12575.3 AIN96547.1 - 2.3 8.0 5.4 5.1 6.9 3.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3753) Herpes_UL73 PF03554.8 AIN96547.1 - 8.3 6.3 8.6 19 5.1 6.0 1.5 1 0 0 1 1 1 0 UL73 viral envelope glycoprotein Dpy-30 PF05186.8 AIN96550.1 - 1.5e-13 49.9 0.6 3e-13 49.0 0.4 1.5 1 0 0 1 1 1 1 Dpy-30 motif AAA_17 PF13207.1 AIN96550.1 - 1.6e-08 35.3 0.0 1.2e-07 32.5 0.0 2.5 3 0 0 3 3 3 1 AAA domain AAA PF00004.24 AIN96550.1 - 0.075 13.2 0.0 0.16 12.1 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Fib_alpha PF08702.5 AIN96551.1 - 7.8 6.6 7.6 2.7 8.1 0.3 2.8 3 0 0 3 3 3 0 Fibrinogen alpha/beta chain family Sin_N PF04801.8 AIN96552.1 - 1.1e-61 208.9 0.1 3.7e-61 207.2 0.1 1.7 2 0 0 2 2 2 1 Sin-like protein conserved region EMP70 PF02990.11 AIN96553.1 - 3.1e-92 309.6 13.5 5.5e-92 308.9 9.4 1.3 1 0 0 1 1 1 1 Endomembrane protein 70 WD40 PF00400.27 AIN96554.1 - 0.00014 21.5 6.3 0.36 10.7 0.0 5.1 6 0 0 6 6 6 2 WD domain, G-beta repeat DUF328 PF03883.9 AIN96554.1 - 0.24 10.6 0.0 0.48 9.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF328) LRR_4 PF12799.2 AIN96557.1 - 2.3e-11 43.0 5.6 1.4e-07 30.9 1.1 3.3 1 1 2 3 3 3 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 AIN96557.1 - 3.3e-06 26.7 20.8 6.6e-05 22.5 2.8 2.5 1 1 2 3 3 3 3 Leucine rich repeat LRR_1 PF00560.28 AIN96557.1 - 0.017 15.0 14.6 2.1 8.6 0.6 4.9 4 1 1 5 5 5 0 Leucine Rich Repeat LRR_7 PF13504.1 AIN96557.1 - 0.084 13.1 12.0 0.57 10.6 0.0 4.3 4 0 0 4 4 4 0 Leucine rich repeat LRR_6 PF13516.1 AIN96557.1 - 0.75 10.0 11.1 17 5.8 0.9 4.4 3 1 1 4 4 4 0 Leucine Rich repeat EF-hand_1 PF00036.27 AIN96559.1 - 3.7e-24 82.1 0.0 1.6e-06 27.0 0.0 5.2 5 0 0 5 5 5 5 EF hand EF-hand_7 PF13499.1 AIN96559.1 - 3.1e-22 78.4 0.0 1.8e-10 40.7 0.0 3.1 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_6 PF13405.1 AIN96559.1 - 1.1e-19 68.4 1.3 0.00046 19.8 0.0 5.2 4 1 1 5 5 5 4 EF-hand domain EF-hand_5 PF13202.1 AIN96559.1 - 7e-16 56.7 1.2 4.2e-06 25.8 0.0 3.7 4 0 0 4 4 4 3 EF hand EF-hand_8 PF13833.1 AIN96559.1 - 8.4e-16 57.3 0.1 0.00019 20.9 0.0 4.6 3 2 2 5 5 5 3 EF-hand domain pair EF-hand_9 PF14658.1 AIN96559.1 - 0.011 15.6 0.0 2.4 8.1 0.0 3.0 2 1 1 3 3 3 0 EF-hand domain EF-hand_10 PF14788.1 AIN96559.1 - 0.053 13.1 0.0 1.2 8.8 0.0 2.8 2 1 1 3 3 3 0 EF hand PAH PF02671.16 AIN96559.1 - 0.11 12.0 0.0 1.8 8.2 0.0 2.4 2 0 0 2 2 2 0 Paired amphipathic helix repeat HECT PF00632.20 AIN96560.1 - 1.7e-43 148.9 0.0 3.6e-43 147.9 0.0 1.5 1 1 0 1 1 1 1 HECT-domain (ubiquitin-transferase) SPRY PF00622.23 AIN96560.1 - 5.3e-27 94.3 2.7 6.2e-11 42.4 0.0 4.0 4 0 0 4 4 4 3 SPRY domain Ran_BP1 PF00638.13 AIN96561.1 - 3.8e-26 91.5 1.5 4.9e-26 91.1 1.1 1.1 1 0 0 1 1 1 1 RanBP1 domain Polyketide_cyc2 PF10604.4 AIN96561.1 - 0.0006 19.9 0.3 0.00074 19.7 0.2 1.2 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport WH1 PF00568.18 AIN96561.1 - 0.032 13.9 0.1 0.041 13.5 0.0 1.3 1 0 0 1 1 1 0 WH1 domain Lactamase_B_2 PF12706.2 AIN96562.1 - 3e-05 23.6 1.1 0.00022 20.8 0.1 2.6 3 0 0 3 3 3 1 Beta-lactamase superfamily domain DRMBL PF07522.9 AIN96562.1 - 0.0043 17.0 0.0 0.0097 15.9 0.0 1.5 1 0 0 1 1 1 1 DNA repair metallo-beta-lactamase PIN_4 PF13638.1 AIN96563.1 - 2.7e-17 63.1 0.0 6e-17 61.9 0.0 1.6 1 0 0 1 1 1 1 PIN domain Metallophos PF00149.23 AIN96564.1 - 5e-28 97.8 0.0 7.4e-28 97.3 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase AAA PF00004.24 AIN96566.1 - 8.9e-16 58.2 0.0 2.4e-15 56.9 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 AIN96566.1 - 0.067 13.3 0.0 0.36 10.9 0.0 2.3 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.1 AIN96566.1 - 0.098 12.6 0.1 0.098 12.6 0.1 3.7 2 2 2 4 4 4 0 AAA ATPase domain RNA_helicase PF00910.17 AIN96566.1 - 0.16 12.1 0.0 1 9.5 0.0 2.3 2 0 0 2 2 2 0 RNA helicase E1-E2_ATPase PF00122.15 AIN96567.1 - 1.1e-20 73.6 0.0 1.1e-20 73.6 0.0 2.4 3 0 0 3 3 3 1 E1-E2 ATPase Hydrolase PF00702.21 AIN96567.1 - 7.9e-13 49.3 0.0 1.1e-11 45.5 0.0 2.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 AIN96567.1 - 4.5e-12 46.5 0.0 1e-11 45.3 0.0 1.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 AIN96567.1 - 8.1e-10 38.5 0.0 3.1e-09 36.6 0.0 1.9 2 0 0 2 2 2 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 AIN96567.1 - 0.023 14.3 0.0 0.051 13.1 0.0 1.5 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase PMC2NT PF08066.7 AIN96568.1 - 0.028 14.6 0.0 0.065 13.5 0.0 1.6 1 0 0 1 1 1 0 PMC2NT (NUC016) domain NIF PF03031.13 AIN96568.1 - 0.22 11.2 0.0 3.6 7.2 0.0 2.2 2 0 0 2 2 2 0 NLI interacting factor-like phosphatase Gtr1_RagA PF04670.7 AIN96570.1 - 1.4e-91 305.8 0.0 1.7e-91 305.4 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Ras PF00071.17 AIN96570.1 - 3e-05 23.4 0.0 0.00012 21.5 0.0 1.9 3 0 0 3 3 3 1 Ras family Arf PF00025.16 AIN96570.1 - 0.00031 20.0 0.0 0.0017 17.6 0.0 2.1 2 0 0 2 2 2 1 ADP-ribosylation factor family Miro PF08477.8 AIN96570.1 - 0.0064 16.9 0.0 0.018 15.5 0.0 1.8 1 0 0 1 1 1 1 Miro-like protein Metallophos PF00149.23 AIN96571.1 - 2.7e-28 98.7 0.0 4.5e-28 98.0 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase UQ_con PF00179.21 AIN96572.1 - 1.1e-14 54.0 0.0 1.1e-14 53.9 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 AIN96572.1 - 0.0014 18.4 0.0 0.0015 18.3 0.0 1.2 1 0 0 1 1 1 1 RWD domain Tcp10_C PF07202.8 AIN96573.1 - 2.1e-26 92.5 0.1 3.6e-26 91.7 0.1 1.4 1 0 0 1 1 1 1 T-complex protein 10 C-terminus HALZ PF02183.13 AIN96573.1 - 0.00024 20.7 2.7 0.0024 17.5 0.3 2.7 2 0 0 2 2 2 1 Homeobox associated leucine zipper DUF3826 PF12875.2 AIN96574.1 - 0.0029 17.3 1.0 0.0029 17.3 0.7 4.2 6 1 0 6 6 6 1 Protein of unknown function (DUF3826) MtrB PF05440.7 AIN96574.1 - 0.074 13.1 0.8 0.97 9.5 0.0 3.5 4 0 0 4 4 4 0 Tetrahydromethanopterin S-methyltransferase subunit B FBP PF07299.6 AIN96574.1 - 1.3 8.3 8.3 0.11 11.8 0.4 3.3 3 1 1 4 4 4 0 Fibronectin-binding protein (FBP) Stm1_N PF09598.5 AIN96574.1 - 5.3 7.8 13.3 0.89 10.2 2.7 3.6 3 0 0 3 3 3 0 Stm1 Kinesin PF00225.18 AIN96575.1 - 2e-92 309.4 0.0 2.8e-92 309.0 0.0 1.2 1 0 0 1 1 1 1 Kinesin motor domain SAM_1 PF00536.25 AIN96575.1 - 3.8e-05 23.7 3.2 6.4e-05 23.0 0.2 2.3 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.12 AIN96575.1 - 0.13 12.1 0.2 0.3 10.9 0.1 1.6 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) SE PF08491.5 AIN96576.1 - 3.6e-59 199.8 0.0 5.1e-59 199.3 0.0 1.2 1 0 0 1 1 1 1 Squalene epoxidase FAD_binding_3 PF01494.14 AIN96576.1 - 4.7e-08 32.4 0.1 2.4e-06 26.8 0.0 2.4 2 1 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.9 AIN96576.1 - 0.011 15.6 0.1 0.026 14.4 0.1 1.5 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase GDI PF00996.13 AIN96576.1 - 0.035 12.4 0.0 0.052 11.8 0.0 1.2 1 0 0 1 1 1 0 GDP dissociation inhibitor Thi4 PF01946.12 AIN96576.1 - 0.042 12.9 0.0 0.07 12.2 0.0 1.2 1 0 0 1 1 1 0 Thi4 family NAD_binding_8 PF13450.1 AIN96576.1 - 0.057 13.4 0.0 0.15 12.1 0.0 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 AIN96576.1 - 0.1 11.5 0.0 5.4 5.8 0.0 2.1 2 0 0 2 2 2 0 Lycopene cyclase protein GIDA PF01134.17 AIN96576.1 - 0.14 11.0 0.1 0.29 9.9 0.0 1.5 2 0 0 2 2 2 0 Glucose inhibited division protein A Pyr_redox PF00070.22 AIN96576.1 - 0.16 12.3 0.1 0.51 10.7 0.0 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DNA_pol_A PF00476.15 AIN96577.1 - 8.5e-33 113.5 0.1 1.8e-32 112.4 0.1 1.4 1 0 0 1 1 1 1 DNA polymerase family A DNA_pol_A_exo1 PF01612.15 AIN96577.1 - 0.00013 21.5 0.0 0.00036 20.0 0.0 1.7 1 0 0 1 1 1 1 3'-5' exonuclease Pkinase PF00069.20 AIN96578.1 - 2.9e-52 177.3 0.0 7.9e-31 107.1 0.0 3.9 3 1 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.12 AIN96578.1 - 3.9e-21 75.2 0.0 3.9e-17 62.1 0.0 2.6 3 0 0 3 3 3 2 Protein tyrosine kinase Kinase-like PF14531.1 AIN96578.1 - 0.027 13.4 0.0 0.46 9.3 0.0 2.7 3 0 0 3 3 3 0 Kinase-like Kdo PF06293.9 AIN96578.1 - 0.033 13.2 0.0 0.06 12.3 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Dynein_heavy PF03028.10 AIN96579.1 - 4.1e-232 772.1 0.0 8.5e-173 576.1 0.0 2.5 2 0 0 2 2 2 2 Dynein heavy chain and region D6 of dynein motor AAA_6 PF12774.2 AIN96579.1 - 1.8e-114 381.0 0.1 6e-114 379.3 0.1 2.0 2 0 0 2 2 2 1 Hydrolytic ATP binding site of dynein motor region D1 DHC_N2 PF08393.8 AIN96579.1 - 1.9e-109 365.9 2.9 1.9e-109 365.9 2.0 3.3 4 0 0 4 4 4 1 Dynein heavy chain, N-terminal region 2 DHC_N1 PF08385.7 AIN96579.1 - 2.1e-106 356.5 0.0 2.1e-106 356.5 0.0 2.8 3 0 0 3 3 3 1 Dynein heavy chain, N-terminal region 1 AAA_8 PF12780.2 AIN96579.1 - 4.7e-95 317.5 0.1 1.1e-94 316.4 0.1 1.7 1 0 0 1 1 1 1 P-loop containing dynein motor region D4 AAA_7 PF12775.2 AIN96579.1 - 2.8e-87 292.2 0.5 8e-87 290.7 0.4 1.8 1 0 0 1 1 1 1 P-loop containing dynein motor region D3 AAA_9 PF12781.2 AIN96579.1 - 1.2e-84 282.6 0.1 2.4e-84 281.7 0.1 1.5 1 0 0 1 1 1 1 ATP-binding dynein motor region D5 MT PF12777.2 AIN96579.1 - 5.6e-84 281.8 10.4 1.2e-83 280.7 7.2 1.6 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_5 PF07728.9 AIN96579.1 - 4.4e-21 75.0 0.1 1.3e-07 31.3 0.0 5.7 5 0 0 5 5 5 3 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 AIN96579.1 - 3.2e-09 37.0 0.0 0.041 13.8 0.0 5.6 4 0 0 4 4 4 2 AAA ATPase domain AAA PF00004.24 AIN96579.1 - 3.3e-06 27.3 0.0 0.13 12.4 0.0 3.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.1 AIN96579.1 - 0.00022 20.9 0.3 11 5.9 0.3 3.9 3 0 0 3 3 3 0 Part of AAA domain AAA_18 PF13238.1 AIN96579.1 - 0.00032 21.0 1.7 6.4 7.0 0.0 5.7 5 0 0 5 5 4 1 AAA domain AAA_17 PF13207.1 AIN96579.1 - 0.0051 17.6 2.4 0.54 11.0 0.0 5.2 5 0 0 5 5 4 1 AAA domain Mg_chelatase PF01078.16 AIN96579.1 - 0.0058 15.8 0.3 0.59 9.2 0.0 3.7 4 0 0 4 4 4 1 Magnesium chelatase, subunit ChlI UPF0079 PF02367.12 AIN96579.1 - 0.015 14.8 0.4 23 4.6 0.0 3.7 3 0 0 3 3 3 0 Uncharacterised P-loop hydrolase UPF0079 Reo_sigmaC PF04582.7 AIN96579.1 - 0.8 8.8 8.5 0.099 11.8 0.2 3.1 3 0 0 3 3 3 0 Reovirus sigma C capsid protein Cpn60_TCP1 PF00118.19 AIN96580.1 - 3.7e-146 487.5 4.3 4.2e-146 487.3 3.0 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Blt1 PF12754.2 AIN96580.1 - 0.2 11.2 0.2 0.44 10.0 0.0 1.6 2 0 0 2 2 2 0 Cell-cycle control medial ring component Ribosomal_L44 PF00935.14 AIN96581.1 - 3e-31 107.2 8.9 4.4e-31 106.7 6.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L44 RPA_interact_C PF14768.1 AIN96581.1 - 0.1 13.0 0.6 0.65 10.4 0.4 1.9 1 1 0 1 1 1 0 Replication protein A interacting C-terminal P5CR_dimer PF14748.1 AIN96582.1 - 7.1e-37 125.6 0.9 1.1e-36 125.0 0.6 1.3 1 0 0 1 1 1 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.12 AIN96582.1 - 1.2e-17 64.1 0.2 2.8e-17 62.9 0.0 1.7 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.10 AIN96582.1 - 2.4e-05 24.2 0.1 4.6e-05 23.3 0.1 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase ApbA PF02558.11 AIN96582.1 - 0.00082 18.8 0.2 0.0016 17.8 0.1 1.6 1 1 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Shikimate_DH PF01488.15 AIN96582.1 - 0.0024 17.9 0.1 0.0041 17.2 0.1 1.6 1 1 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase IlvN PF07991.7 AIN96582.1 - 0.0079 15.5 0.0 0.012 14.9 0.0 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain NAD_Gly3P_dh_N PF01210.18 AIN96582.1 - 0.016 14.9 1.6 0.14 11.8 1.1 2.1 1 1 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus CbiC PF02570.10 AIN96582.1 - 0.066 12.6 0.1 0.18 11.2 0.1 1.6 2 0 0 2 2 2 0 Precorrin-8X methylmutase ATP-synt_A PF00119.15 AIN96582.1 - 0.14 11.5 0.1 0.2 11.1 0.1 1.2 1 0 0 1 1 1 0 ATP synthase A chain MFS_1 PF07690.11 AIN96583.1 - 5.8e-12 44.9 36.1 5.6e-09 35.1 19.0 2.4 2 0 0 2 2 2 2 Major Facilitator Superfamily Nodulin-like PF06813.8 AIN96583.1 - 4.6e-07 29.3 15.8 4.6e-07 29.3 10.9 3.0 2 2 0 2 2 2 1 Nodulin-like LRR_4 PF12799.2 AIN96584.1 - 5.2e-14 51.4 0.0 0.053 13.1 0.0 5.7 5 1 1 6 6 6 4 Leucine Rich repeats (2 copies) LRR_7 PF13504.1 AIN96584.1 - 0.00049 19.8 3.9 40 5.0 0.0 6.2 5 1 0 5 5 5 0 Leucine rich repeat LRR_6 PF13516.1 AIN96584.1 - 0.0022 17.8 1.1 80 3.7 0.0 5.1 5 0 0 5 5 5 0 Leucine Rich repeat LRR_1 PF00560.28 AIN96584.1 - 0.0046 16.7 0.5 16 6.0 0.1 5.8 5 1 0 5 5 5 1 Leucine Rich Repeat SPO11_like PF03533.9 AIN96585.1 - 0.19 11.6 0.8 1.6 8.6 0.2 2.3 2 0 0 2 2 2 0 SPO11 homologue Daxx PF03344.10 AIN96586.1 - 0.031 12.7 1.9 0.044 12.2 1.3 1.1 1 0 0 1 1 1 0 Daxx Family FAA_hydrolase_N PF09298.6 AIN96586.1 - 0.29 11.1 1.4 8.7 6.3 0.1 2.6 1 1 0 2 2 2 0 Fumarylacetoacetase N-terminal Tet_JBP PF12851.2 AIN96587.1 - 1.6e-25 89.3 0.9 2.6e-25 88.6 0.1 1.8 2 0 0 2 2 2 1 Oxygenase domain of the 2OGFeDO superfamily SNF2_N PF00176.18 AIN96587.1 - 3.2e-25 88.5 0.0 6.1e-25 87.6 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 AIN96587.1 - 1.2e-11 44.2 0.0 2.8e-11 43.0 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 AIN96587.1 - 6.8e-06 26.0 0.0 3e-05 23.9 0.0 2.0 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.24 AIN96587.1 - 0.0062 16.0 0.0 0.023 14.2 0.0 2.0 2 1 0 2 2 2 1 DEAD/DEAH box helicase DUF2095 PF09868.4 AIN96587.1 - 0.065 13.0 0.1 0.2 11.4 0.0 1.8 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2095) cNMP_binding PF00027.24 AIN96588.1 - 0.0028 17.4 0.0 0.044 13.5 0.0 2.5 2 0 0 2 2 2 1 Cyclic nucleotide-binding domain Arf PF00025.16 AIN96589.1 - 0.00035 19.8 0.0 0.00081 18.6 0.0 1.5 1 1 0 1 1 1 1 ADP-ribosylation factor family AAA_28 PF13521.1 AIN96589.1 - 0.0046 16.9 0.2 0.0079 16.1 0.2 1.4 1 0 0 1 1 1 1 AAA domain Miro PF08477.8 AIN96589.1 - 0.032 14.7 0.0 0.053 14.0 0.0 1.4 1 0 0 1 1 1 0 Miro-like protein Arch_ATPase PF01637.13 AIN96589.1 - 0.16 11.6 0.0 0.27 10.9 0.0 1.3 1 0 0 1 1 1 0 Archaeal ATPase zf-DHHC PF01529.15 AIN96590.1 - 2.8e-23 82.1 13.7 2.8e-23 82.1 9.5 1.7 1 1 0 1 1 1 1 DHHC palmitoyltransferase 7tm_7 PF08395.7 AIN96590.1 - 0.012 14.6 13.7 0.013 14.5 8.9 1.3 1 1 0 1 1 1 0 7tm Chemosensory receptor stn_TNFRSF12A PF12191.3 AIN96590.1 - 0.76 9.8 7.0 0.48 10.4 2.6 2.3 2 1 0 2 2 2 0 Tumour necrosis factor receptor stn_TNFRSF12A_TNFR domain PRP1_N PF06424.7 AIN96591.1 - 0.047 14.0 0.1 0.047 14.0 0.1 1.8 2 0 0 2 2 2 0 PRP1 splicing factor, N-terminal DnaJ PF00226.26 AIN96592.1 - 0.0021 17.7 0.0 0.0047 16.6 0.0 1.6 1 0 0 1 1 1 1 DnaJ domain CH PF00307.26 AIN96593.1 - 0.00059 19.8 0.0 0.0027 17.7 0.0 2.2 2 0 0 2 2 2 1 Calponin homology (CH) domain NCD2 PF04905.8 AIN96593.1 - 0.0023 17.7 0.3 4.6 7.0 0.2 3.2 3 0 0 3 3 3 2 NAB conserved region 2 (NCD2) IFT57 PF10498.4 AIN96593.1 - 0.44 9.2 10.8 0.76 8.4 7.5 1.3 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 DnaJ PF00226.26 AIN96594.1 - 1.3e-13 50.4 1.0 2.3e-13 49.6 0.7 1.5 1 0 0 1 1 1 1 DnaJ domain TAFH PF07531.9 AIN96594.1 - 0.06 12.9 0.1 14 5.3 0.0 2.5 2 0 0 2 2 2 0 NHR1 homology to TAF IU_nuc_hydro PF01156.14 AIN96596.1 - 1.7e-70 237.6 0.1 2.1e-70 237.4 0.1 1.0 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase MOZ_SAS PF01853.13 AIN96597.1 - 5e-62 208.4 0.0 7.4e-62 207.9 0.0 1.2 1 0 0 1 1 1 1 MOZ/SAS family Tudor-knot PF11717.3 AIN96597.1 - 1.1e-08 34.6 0.6 2.5e-08 33.5 0.1 1.9 2 0 0 2 2 2 1 RNA binding activity-knot of a chromodomain Acetyltransf_1 PF00583.19 AIN96597.1 - 0.026 14.5 0.0 0.087 12.8 0.0 1.8 2 0 0 2 2 2 0 Acetyltransferase (GNAT) family DUF4286 PF14114.1 AIN96597.1 - 0.11 12.7 0.2 0.42 10.9 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4286) zf-Di19 PF05605.7 AIN96597.1 - 0.48 10.5 5.9 2.1 8.5 0.6 2.5 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding Ribosomal_L12 PF00542.14 AIN96598.1 - 2.3e-16 59.5 3.4 2.3e-16 59.5 2.4 1.6 2 0 0 2 2 2 1 Ribosomal protein L7/L12 C-terminal domain DUF3138 PF11336.3 AIN96598.1 - 0.054 11.6 1.0 0.068 11.3 0.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) PepSY_2 PF13670.1 AIN96598.1 - 0.26 11.2 10.8 2.4 8.1 2.2 2.8 3 0 0 3 3 3 0 Peptidase propeptide and YPEB domain Ribosomal_60s PF00428.14 AIN96598.1 - 4.7 7.6 20.5 0.44 10.9 10.3 2.3 1 1 2 3 3 3 0 60s Acidic ribosomal protein Chromo PF00385.19 AIN96599.1 - 0.0011 18.5 0.2 0.002 17.7 0.1 1.4 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Thioredoxin_8 PF13905.1 AIN96601.1 - 2.8e-08 33.7 0.1 4.1e-08 33.2 0.1 1.2 1 0 0 1 1 1 1 Thioredoxin-like AhpC-TSA PF00578.16 AIN96601.1 - 0.00017 21.2 0.0 0.00022 20.8 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 AIN96601.1 - 0.00034 20.1 0.1 0.0004 19.9 0.1 1.2 1 0 0 1 1 1 1 Redoxin BBIP10 PF14777.1 AIN96602.1 - 1.5e-12 46.6 2.6 2.6e-12 45.9 1.8 1.3 1 0 0 1 1 1 1 Cilia BBSome complex subunit 10 DUF4201 PF13870.1 AIN96603.1 - 1.2e-31 109.5 9.5 1.2e-31 109.5 6.6 2.7 2 1 0 2 2 2 1 Domain of unknown function (DUF4201) TMCO5 PF14992.1 AIN96603.1 - 5.4 6.0 15.3 0.22 10.6 0.7 3.3 3 1 0 3 3 3 0 TMCO5 family bZIP_1 PF00170.16 AIN96603.1 - 6.8 6.7 16.0 0.15 12.0 0.6 4.0 4 0 0 4 4 4 0 bZIP transcription factor PX PF00787.19 AIN96604.1 - 2.4e-09 36.9 0.2 1.4e-08 34.5 0.0 2.3 3 0 0 3 3 3 1 PX domain Sec5 PF15469.1 AIN96605.1 - 1.1e-06 28.5 0.0 2.3e-06 27.4 0.0 1.5 1 0 0 1 1 1 1 Exocyst complex component Sec5 BAF1_ABF1 PF04684.8 AIN96605.1 - 0.051 12.4 9.9 0.14 11.0 6.9 1.7 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor DUF3161 PF11362.3 AIN96605.1 - 0.22 11.4 0.0 0.62 10.0 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3161) HIT PF01230.18 AIN96606.1 - 1.7e-23 83.0 0.0 2.2e-23 82.6 0.0 1.2 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.3 AIN96606.1 - 5.5e-14 52.3 0.0 6.9e-14 52.0 0.0 1.1 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding CwfJ_C_1 PF04677.10 AIN96606.1 - 0.00052 19.6 1.1 0.0015 18.1 0.8 1.8 1 1 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 DUF834 PF05754.9 AIN96606.1 - 0.14 11.9 0.3 0.25 11.1 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF834) TRAP-gamma PF07074.7 AIN96607.1 - 3.2e-08 33.2 2.9 0.00055 19.5 0.1 2.1 2 0 0 2 2 2 2 Translocon-associated protein, gamma subunit (TRAP-gamma) DUF2721 PF11026.3 AIN96607.1 - 0.079 12.5 1.0 0.12 11.9 0.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2721) DUF3272 PF11676.3 AIN96607.1 - 0.11 12.5 2.5 14 5.7 0.1 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3272) VWA_3 PF13768.1 AIN96608.1 - 1.5e-08 34.5 0.2 5.1e-08 32.7 0.2 2.0 1 1 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.1 AIN96608.1 - 0.0041 17.2 0.3 0.0041 17.2 0.2 2.2 2 1 0 2 2 2 1 von Willebrand factor type A domain VIT_2 PF13757.1 AIN96608.1 - 0.025 14.0 0.1 0.11 12.0 0.1 2.1 1 0 0 1 1 1 0 Vault protein inter-alpha-trypsin domain BESS PF02944.15 AIN96608.1 - 0.12 11.9 0.0 0.23 11.0 0.0 1.5 1 0 0 1 1 1 0 BESS motif MutS_III PF05192.13 AIN96609.1 - 0.0067 16.2 0.3 0.073 12.8 0.0 2.3 2 0 0 2 2 2 1 MutS domain III Epimerase PF01370.16 AIN96610.1 - 1.9e-08 34.0 0.2 0.0048 16.3 0.0 2.5 2 1 0 2 2 2 2 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 AIN96610.1 - 8.3e-08 32.4 0.1 0.00071 19.6 0.1 2.5 2 1 0 2 2 2 2 NADH(P)-binding adh_short PF00106.20 AIN96610.1 - 1.9e-05 24.6 2.4 0.019 14.9 0.1 2.6 2 1 1 3 3 3 2 short chain dehydrogenase NAD_binding_4 PF07993.7 AIN96610.1 - 0.0001 21.3 0.2 0.023 13.6 0.0 2.4 2 1 0 2 2 2 2 Male sterility protein RmlD_sub_bind PF04321.12 AIN96610.1 - 0.0036 16.2 0.5 0.72 8.6 0.1 2.7 2 1 0 2 2 2 2 RmlD substrate binding domain NmrA PF05368.8 AIN96610.1 - 0.026 13.7 0.1 0.047 12.9 0.0 1.4 1 0 0 1 1 1 0 NmrA-like family 3Beta_HSD PF01073.14 AIN96610.1 - 0.15 10.7 1.1 1.2 7.8 0.0 2.4 2 1 0 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family Proteasome PF00227.21 AIN96612.1 - 1.9e-50 170.8 0.0 2.5e-50 170.3 0.0 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 AIN96612.1 - 8.9e-14 50.5 0.4 1.5e-13 49.7 0.3 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature DUF2064 PF09837.4 AIN96612.1 - 0.0066 16.0 0.0 0.022 14.3 0.0 1.9 1 1 1 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2064) AA_permease_2 PF13520.1 AIN96613.1 - 6.6e-35 120.4 39.4 9.4e-35 119.9 27.1 1.3 1 1 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 AIN96613.1 - 9e-12 44.0 37.2 2.1e-11 42.8 25.8 1.5 1 1 0 1 1 1 1 Amino acid permease Aa_trans PF01490.13 AIN96614.1 - 9.4e-24 83.6 18.7 1.3e-23 83.1 12.9 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein IPK PF03770.11 AIN96615.1 - 4.2e-42 144.0 0.1 8.9e-42 142.9 0.1 1.6 1 0 0 1 1 1 1 Inositol polyphosphate kinase PALP PF00291.20 AIN96616.1 - 7.1e-13 48.4 0.0 1.5e-12 47.3 0.0 1.5 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Thr_synth_N PF14821.1 AIN96616.1 - 1.7e-12 47.1 0.0 5.5e-12 45.5 0.0 2.0 1 0 0 1 1 1 1 Threonine synthase N terminus zf-CW PF07496.10 AIN96617.1 - 5.3e-05 22.8 3.1 0.00013 21.5 2.2 1.7 1 0 0 1 1 1 1 CW-type Zinc Finger zf-DNL PF05180.7 AIN96617.1 - 0.071 12.8 0.5 0.14 11.8 0.3 1.4 1 0 0 1 1 1 0 DNL zinc finger Bromodomain PF00439.20 AIN96617.1 - 0.077 12.9 0.0 0.41 10.5 0.0 2.0 1 1 0 1 1 1 0 Bromodomain Choline_transpo PF04515.7 AIN96619.1 - 1.4e-74 250.8 39.1 3.1e-74 249.6 27.1 1.5 1 0 0 1 1 1 1 Plasma-membrane choline transporter ATP-synt_D PF01813.12 AIN96620.1 - 0.027 14.0 0.1 0.69 9.4 0.0 2.1 2 0 0 2 2 2 0 ATP synthase subunit D DUF1253 PF06862.7 AIN96621.1 - 3.2e-123 411.4 0.0 4.2e-123 411.0 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1253) Dzip-like_N PF13815.1 AIN96622.1 - 4e-39 133.0 1.3 4e-39 133.0 0.9 2.2 3 0 0 3 3 3 1 Iguana/Dzip1-like DAZ-interacting protein N-terminal zf-Di19 PF05605.7 AIN96622.1 - 0.00029 20.9 0.9 0.00042 20.3 0.0 1.7 2 0 0 2 2 2 1 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_4 PF13894.1 AIN96622.1 - 0.025 14.8 0.9 0.059 13.7 0.6 1.6 1 0 0 1 1 1 0 C2H2-type zinc finger zf-C2H2_2 PF12756.2 AIN96622.1 - 0.072 13.2 0.5 0.34 11.0 0.0 2.0 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-C2H2 PF00096.21 AIN96622.1 - 0.1 12.9 1.4 0.22 11.9 1.0 1.6 1 0 0 1 1 1 0 Zinc finger, C2H2 type DUF3505 PF12013.3 AIN96622.1 - 0.11 12.6 0.6 1.4 9.1 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3505) mRNA_triPase PF02940.10 AIN96623.1 - 2e-10 40.7 0.0 7.1e-08 32.4 0.0 3.0 2 1 0 2 2 2 2 mRNA capping enzyme, beta chain Pyr_redox_2 PF07992.9 AIN96624.1 - 1.4e-12 47.9 0.0 2.4e-06 27.5 0.0 3.8 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 AIN96624.1 - 4.3e-09 36.6 0.0 1.3e-05 25.5 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 AIN96624.1 - 5.3e-08 32.1 0.0 0.00046 19.2 0.0 3.1 3 0 0 3 3 3 2 Lycopene cyclase protein NAD_binding_9 PF13454.1 AIN96624.1 - 1.7e-06 27.9 0.0 0.02 14.6 0.0 3.5 3 0 0 3 3 3 2 FAD-NAD(P)-binding Pyr_redox_3 PF13738.1 AIN96624.1 - 3.1e-06 27.4 0.0 7.5e-05 22.8 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 AIN96624.1 - 1.6e-05 24.8 0.0 0.11 12.5 0.0 2.8 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain DAO PF01266.19 AIN96624.1 - 3.5e-05 22.8 0.0 0.05 12.5 0.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase K_oxygenase PF13434.1 AIN96624.1 - 0.00029 19.8 0.0 0.0011 17.9 0.0 1.9 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) GIDA PF01134.17 AIN96624.1 - 0.0054 15.6 0.0 1.7 7.4 0.0 2.8 3 0 0 3 3 3 1 Glucose inhibited division protein A FAD_binding_3 PF01494.14 AIN96624.1 - 0.026 13.5 0.0 0.35 9.8 0.0 2.1 2 0 0 2 2 2 0 FAD binding domain NAD_Gly3P_dh_N PF01210.18 AIN96624.1 - 0.027 14.1 0.0 0.069 12.8 0.0 1.7 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Thi4 PF01946.12 AIN96624.1 - 0.032 13.3 0.0 0.36 9.8 0.0 2.1 2 0 0 2 2 2 0 Thi4 family 3HCDH_N PF02737.13 AIN96624.1 - 0.045 13.3 0.0 0.54 9.8 0.0 2.2 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_7 PF13241.1 AIN96624.1 - 0.052 13.8 0.0 12 6.2 0.0 2.5 2 0 0 2 2 2 0 Putative NAD(P)-binding Shikimate_DH PF01488.15 AIN96624.1 - 0.12 12.4 0.0 28 4.8 0.0 3.1 3 0 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase Trp_halogenase PF04820.9 AIN96624.1 - 0.13 10.8 0.0 9.1 4.7 0.0 2.4 3 0 0 3 3 3 0 Tryptophan halogenase Nudc_N PF14050.1 AIN96625.1 - 5.3e-18 64.7 0.2 1.2e-17 63.5 0.1 1.6 1 0 0 1 1 1 1 N-terminal conserved domain of Nudc. CS PF04969.11 AIN96625.1 - 3.6e-15 56.2 0.0 6.2e-15 55.4 0.0 1.4 1 0 0 1 1 1 1 CS domain Borrelia_P83 PF05262.6 AIN96625.1 - 8.6e-05 20.9 14.3 0.00011 20.6 9.9 1.1 1 0 0 1 1 1 1 Borrelia P83/100 protein KTI12 PF08433.5 AIN96625.1 - 0.1 11.7 3.1 0.88 8.7 0.0 2.2 2 0 0 2 2 2 0 Chromatin associated protein KTI12 DUF4407 PF14362.1 AIN96625.1 - 0.71 8.7 15.8 1.1 8.1 11.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Cys_Met_Meta_PP PF01053.15 AIN96626.1 - 6.8e-115 383.4 0.0 8.5e-115 383.1 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.14 AIN96626.1 - 7.2e-05 21.6 0.1 0.00012 20.9 0.1 1.3 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.16 AIN96626.1 - 0.00049 19.1 0.0 0.00088 18.3 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 AIN96626.1 - 0.02 14.0 0.0 0.041 13.0 0.0 1.5 1 0 0 1 1 1 0 Beta-eliminating lyase UDPGT PF00201.13 AIN96627.1 - 5.8e-29 100.9 0.0 2.1e-28 99.1 0.0 1.8 1 1 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Amastin PF07344.6 AIN96628.1 - 1.2e-07 31.4 14.0 1.2e-07 31.4 9.7 2.1 1 1 1 2 2 2 1 Amastin surface glycoprotein Abhydrolase_9_N PF15420.1 AIN96628.1 - 2.4 7.8 11.9 0.08 12.6 2.1 2.2 2 0 0 2 2 2 0 Alpha/beta-hydrolase family N-terminus Amastin PF07344.6 AIN96629.1 - 8.9e-08 31.8 13.5 8.9e-08 31.8 9.4 2.1 1 1 1 2 2 2 1 Amastin surface glycoprotein Abhydrolase_9_N PF15420.1 AIN96629.1 - 2.6 7.7 12.1 0.081 12.6 2.1 2.2 2 0 0 2 2 2 0 Alpha/beta-hydrolase family N-terminus SH3_9 PF14604.1 AIN96630.1 - 0.0016 17.9 0.0 0.043 13.3 0.0 2.8 2 1 0 2 2 2 1 Variant SH3 domain SH3_2 PF07653.12 AIN96630.1 - 0.004 16.6 0.0 0.0095 15.4 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain Hemerythrin PF01814.18 AIN96630.1 - 0.11 12.7 2.1 2.7 8.1 0.0 3.3 3 0 0 3 3 3 0 Hemerythrin HHE cation binding domain FA_desaturase PF00487.19 AIN96631.1 - 4.4e-13 49.2 26.7 4.4e-13 49.2 18.5 2.1 1 1 1 2 2 2 2 Fatty acid desaturase Cyt-b5 PF00173.23 AIN96631.1 - 7.2e-11 41.7 0.0 8.7e-07 28.6 0.0 2.5 2 0 0 2 2 2 2 Cytochrome b5-like Heme/Steroid binding domain Scaffolding_pro PF11418.3 AIN96632.1 - 0.076 13.3 0.8 0.09 13.1 0.5 1.3 1 1 0 1 1 1 0 Phi29 scaffolding protein Ion_trans_2 PF07885.11 AIN96633.1 - 1.9e-07 30.6 6.4 1.9e-07 30.6 4.4 2.0 2 0 0 2 2 2 1 Ion channel IQ PF00612.22 AIN96633.1 - 0.021 14.4 0.1 0.077 12.6 0.0 2.0 1 0 0 1 1 1 0 IQ calmodulin-binding motif Ion_trans_2 PF07885.11 AIN96634.1 - 1.8e-10 40.3 7.0 1.8e-10 40.3 4.9 2.2 2 0 0 2 2 2 1 Ion channel Lig_chan PF00060.21 AIN96634.1 - 0.0037 16.9 2.8 0.0037 16.9 2.0 2.1 2 1 0 2 2 2 1 Ligand-gated ion channel Ion_trans PF00520.26 AIN96634.1 - 0.014 14.6 15.6 0.15 11.3 10.8 2.6 1 1 0 1 1 1 0 Ion transport protein IQ PF00612.22 AIN96634.1 - 2.8 7.8 6.2 0.91 9.3 1.1 2.7 2 0 0 2 2 2 0 IQ calmodulin-binding motif T2SM PF04612.7 AIN96635.1 - 0.0005 19.8 0.0 0.0005 19.8 0.0 2.4 4 0 0 4 4 4 1 Type II secretion system (T2SS), protein M IncA PF04156.9 AIN96635.1 - 0.0045 16.6 0.0 0.0074 15.9 0.0 1.2 1 0 0 1 1 1 1 IncA protein DUF3496 PF12001.3 AIN96635.1 - 0.11 12.7 0.1 0.21 11.8 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3496) TSC22 PF01166.13 AIN96635.1 - 0.27 11.2 1.5 9.6 6.2 0.3 2.6 3 0 0 3 3 3 0 TSC-22/dip/bun family WD40 PF00400.27 AIN96637.1 - 1.8e-30 103.6 15.9 1.3e-06 28.0 0.1 10.0 10 0 0 10 10 10 6 WD domain, G-beta repeat Utp12 PF04003.7 AIN96637.1 - 3.6e-05 23.6 0.2 6.4e-05 22.8 0.1 1.4 1 0 0 1 1 1 1 Dip2/Utp12 Family Nup160 PF11715.3 AIN96637.1 - 0.022 12.8 1.8 0.61 8.1 0.2 2.6 2 0 0 2 2 2 0 Nucleoporin Nup120/160 Complex1_LYR PF05347.10 AIN96638.1 - 0.03 14.1 0.8 0.053 13.3 0.5 1.4 1 0 0 1 1 1 0 Complex 1 protein (LYR family) SpoU_methylase PF00588.14 AIN96640.1 - 4e-10 39.7 0.0 0.00035 20.4 0.0 2.4 2 0 0 2 2 2 2 SpoU rRNA Methylase family Spt5_N PF11942.3 AIN96641.1 - 0.014 15.9 2.7 0.014 15.9 1.9 2.3 3 0 0 3 3 3 0 Spt5 transcription elongation factor, acidic N-terminal DUF3366 PF11846.3 AIN96641.1 - 0.035 13.9 0.2 0.065 13.1 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3366) zf-LSD1 PF06943.7 AIN96643.1 - 1.5e-07 30.8 8.4 1.5e-07 30.8 5.8 3.3 4 0 0 4 4 4 1 LSD1 zinc finger zinc_ribbon_4 PF13717.1 AIN96643.1 - 0.016 14.8 0.5 0.016 14.8 0.3 3.4 4 0 0 4 4 4 0 zinc-ribbon domain zinc_ribbon_5 PF13719.1 AIN96643.1 - 0.017 14.7 0.5 0.017 14.7 0.3 3.3 4 0 0 4 4 4 0 zinc-ribbon domain zf-NADH-PPase PF09297.6 AIN96643.1 - 0.49 9.9 6.7 0.36 10.3 2.7 2.3 2 0 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain OrfB_Zn_ribbon PF07282.6 AIN96643.1 - 7.1 6.3 8.1 2.1 8.0 0.6 2.5 1 1 1 2 2 2 0 Putative transposase DNA-binding domain PHD PF00628.24 AIN96643.1 - 9.5 6.0 9.8 0.12 12.0 0.6 2.3 3 0 0 3 3 3 0 PHD-finger ELO PF01151.13 AIN96644.1 - 1.5e-37 129.2 11.3 1.7e-37 129.0 7.8 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family ELO PF01151.13 AIN96645.1 - 1.1e-64 218.1 17.7 1.3e-64 217.9 12.3 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family ELO PF01151.13 AIN96646.1 - 5.2e-61 206.1 14.4 6e-61 205.8 10.0 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family ELO PF01151.13 AIN96647.1 - 1.6e-61 207.7 13.7 1.9e-61 207.5 9.5 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family ELO PF01151.13 AIN96648.1 - 1.7e-68 230.6 5.0 2e-68 230.4 3.5 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family Bestrophin PF01062.16 AIN96648.1 - 0.07 12.0 2.2 0.12 11.2 1.5 1.3 1 0 0 1 1 1 0 Bestrophin, RFP-TM, chloride channel MadM PF03818.8 AIN96648.1 - 0.39 10.3 2.2 6.6 6.3 0.1 3.0 3 0 0 3 3 3 0 Malonate/sodium symporter MadM subunit ELO PF01151.13 AIN96649.1 - 8e-80 267.7 21.5 9.3e-80 267.5 14.9 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family ELO PF01151.13 AIN96650.1 - 6e-84 281.2 17.1 7.8e-84 280.8 11.8 1.1 1 0 0 1 1 1 1 GNS1/SUR4 family ELO PF01151.13 AIN96651.1 - 1.1e-66 224.7 23.1 1.3e-66 224.5 16.0 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family ELO PF01151.13 AIN96652.1 - 4.8e-70 235.7 24.4 5.9e-70 235.4 16.9 1.1 1 0 0 1 1 1 1 GNS1/SUR4 family ELO PF01151.13 AIN96653.1 - 2.4e-78 262.8 21.1 3e-78 262.5 14.7 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family Ribosomal_L21p PF00829.16 AIN96656.1 - 2.2e-19 69.3 0.0 3.1e-19 68.9 0.0 1.2 1 0 0 1 1 1 1 Ribosomal prokaryotic L21 protein CDC45 PF02724.9 AIN96658.1 - 0.015 13.4 0.2 0.021 12.8 0.1 1.2 1 0 0 1 1 1 0 CDC45-like protein DUF1682 PF07946.9 AIN96658.1 - 0.1 11.4 0.6 0.17 10.6 0.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) DUF4201 PF13870.1 AIN96659.1 - 2.9e-29 101.7 16.7 2.9e-29 101.7 11.6 3.1 4 0 0 4 4 4 1 Domain of unknown function (DUF4201) KxDL PF10241.4 AIN96659.1 - 0.0013 18.6 1.4 0.0013 18.6 0.9 3.3 4 0 0 4 4 4 1 Uncharacterized conserved protein SlyX PF04102.7 AIN96659.1 - 0.11 12.9 0.0 0.11 12.9 0.0 6.2 4 2 3 8 8 8 0 SlyX Phycoerythr_ab PF02972.9 AIN96659.1 - 0.66 9.6 2.8 2.2 7.9 0.5 2.8 2 0 0 2 2 2 0 Phycoerythrin, alpha/beta chain DUF948 PF06103.6 AIN96659.1 - 7.2 6.5 12.6 8.5 6.3 0.1 3.7 3 1 0 4 4 4 0 Bacterial protein of unknown function (DUF948) Pkinase PF00069.20 AIN96660.1 - 8.5e-44 149.6 0.0 6.3e-24 84.5 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 AIN96660.1 - 2e-12 46.7 0.0 3.9e-08 32.6 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.18 AIN96660.1 - 4.8e-05 23.2 0.0 8.5e-05 22.3 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 AIN96660.1 - 0.03 13.8 0.0 0.045 13.3 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase RIO1 PF01163.17 AIN96660.1 - 0.049 12.9 0.0 0.078 12.3 0.0 1.2 1 0 0 1 1 1 0 RIO1 family SNF2_N PF00176.18 AIN96661.1 - 2.5e-61 207.0 0.0 4.8e-61 206.1 0.0 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 AIN96661.1 - 1.6e-14 53.5 0.2 1.3e-13 50.5 0.0 2.6 2 1 0 2 2 2 1 Helicase conserved C-terminal domain V_ATPase_I PF01496.14 AIN96661.1 - 4.3 5.0 8.0 8 4.1 5.6 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF1935 PF09149.5 AIN96662.1 - 6e-38 128.9 0.3 6.8e-38 128.8 0.2 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1935) PP2C PF00481.16 AIN96665.1 - 3.9e-48 164.0 0.0 1.6e-47 162.1 0.0 1.9 1 1 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.1 AIN96665.1 - 2.1e-08 33.8 0.0 1.1e-07 31.5 0.0 2.1 1 1 0 1 1 1 1 Protein phosphatase 2C GSH_synth_ATP PF03917.12 AIN96666.1 - 3.2e-59 200.4 0.0 3e-56 190.6 0.0 3.6 1 1 0 1 1 1 1 Eukaryotic glutathione synthase, ATP binding domain GSH_synthase PF03199.10 AIN96666.1 - 2.7e-34 117.4 0.1 5.9e-34 116.3 0.0 1.6 1 0 0 1 1 1 1 Eukaryotic glutathione synthase DNA_pol_A PF00476.15 AIN96667.1 - 4.9e-28 97.8 0.0 8.2e-28 97.0 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase family A TINF2_N PF14973.1 AIN96668.1 - 0.083 13.0 0.9 5.7 7.0 0.0 2.6 2 0 0 2 2 2 0 TERF1-interacting nuclear factor 2 N-terminus AAA_13 PF13166.1 AIN96668.1 - 0.91 7.9 3.9 7 4.9 2.6 2.1 1 1 0 1 1 1 0 AAA domain SlyX PF04102.7 AIN96668.1 - 4.5 7.7 10.0 27 5.2 0.0 3.9 3 1 1 4 4 4 0 SlyX Ribosomal_L16 PF00252.13 AIN96670.1 - 9.3e-23 80.4 0.0 1.2e-22 80.1 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e PAP_assoc PF03828.14 AIN96671.1 - 5.2e-16 58.3 0.0 3.2e-11 43.0 0.0 2.8 3 0 0 3 3 3 2 Cid1 family poly A polymerase NTP_transf_2 PF01909.18 AIN96671.1 - 0.011 16.0 0.1 0.084 13.2 0.0 2.2 2 0 0 2 2 2 0 Nucleotidyltransferase domain AAA_18 PF13238.1 AIN96672.1 - 1.2e-07 32.0 0.0 0.01 16.1 0.0 2.3 2 0 0 2 2 2 2 AAA domain PRK PF00485.13 AIN96672.1 - 0.00013 21.6 0.0 0.033 13.7 0.0 2.2 2 0 0 2 2 2 2 Phosphoribulokinase / Uridine kinase family AAA_17 PF13207.1 AIN96672.1 - 0.0004 21.1 0.2 0.0013 19.5 0.1 2.0 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 AIN96672.1 - 0.0053 16.4 0.0 0.011 15.4 0.0 1.5 1 0 0 1 1 1 1 Part of AAA domain AAA_25 PF13481.1 AIN96672.1 - 0.045 13.1 0.0 0.066 12.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain NAD_binding_10 PF13460.1 AIN96672.1 - 0.061 13.3 0.2 0.9 9.5 0.0 2.5 2 1 1 3 3 3 0 NADH(P)-binding Zeta_toxin PF06414.7 AIN96672.1 - 0.099 11.7 0.0 0.2 10.7 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin RNA_helicase PF00910.17 AIN96672.1 - 0.11 12.6 0.0 0.2 11.8 0.0 1.4 1 0 0 1 1 1 0 RNA helicase ABC_tran PF00005.22 AIN96672.1 - 0.12 12.6 0.0 0.2 11.9 0.0 1.3 1 0 0 1 1 1 0 ABC transporter MMR_HSR1 PF01926.18 AIN96672.1 - 0.14 12.1 0.0 0.53 10.2 0.0 1.9 2 0 0 2 2 2 0 50S ribosome-binding GTPase Na_H_Exchanger PF00999.16 AIN96673.1 - 1.8e-19 69.5 24.0 3.3e-19 68.6 16.6 1.4 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family TMEM138 PF14935.1 AIN96673.1 - 0.13 12.5 1.9 0.92 9.8 0.3 2.7 2 0 0 2 2 2 0 Transmembrane protein 138 FixQ PF05545.6 AIN96673.1 - 1.7 8.3 0.0 1.7 8.3 0.0 3.3 3 0 0 3 3 3 0 Cbb3-type cytochrome oxidase component FixQ Mito_carr PF00153.22 AIN96674.1 - 2.4e-27 94.4 0.0 2e-12 46.6 0.0 3.5 3 1 0 3 3 3 3 Mitochondrial carrier protein Mito_carr PF00153.22 AIN96675.1 - 1e-08 34.7 0.1 0.0015 18.1 0.0 3.6 3 1 0 3 3 3 3 Mitochondrial carrier protein DUF202 PF02656.10 AIN96679.1 - 3.3e-15 56.0 0.8 4.2e-14 52.5 0.1 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF202) Abhydrolase_9_N PF15420.1 AIN96679.1 - 0.07 12.8 0.2 0.092 12.4 0.1 1.1 1 0 0 1 1 1 0 Alpha/beta-hydrolase family N-terminus COQ9 PF08511.6 AIN96681.1 - 0.0002 20.7 0.0 0.0008 18.8 0.0 2.0 2 0 0 2 2 2 1 COQ9 Dynein_heavy PF03028.10 AIN96682.1 - 2.4e-133 445.7 0.0 7.7e-77 258.9 0.0 3.8 3 1 0 3 3 3 2 Dynein heavy chain and region D6 of dynein motor DHC_N2 PF08393.8 AIN96682.1 - 5.6e-119 397.2 2.4 6e-119 397.1 0.0 2.2 2 0 0 2 2 2 1 Dynein heavy chain, N-terminal region 2 AAA_6 PF12774.2 AIN96682.1 - 7.2e-95 316.8 0.4 1.5e-94 315.8 0.0 1.8 2 0 0 2 2 2 1 Hydrolytic ATP binding site of dynein motor region D1 AAA_8 PF12780.2 AIN96682.1 - 1e-59 201.7 0.0 2.2e-59 200.6 0.0 1.6 1 0 0 1 1 1 1 P-loop containing dynein motor region D4 MT PF12777.2 AIN96682.1 - 1.7e-42 145.4 3.6 1.7e-42 145.4 2.5 2.1 3 0 0 3 3 3 1 Microtubule-binding stalk of dynein motor AAA_9 PF12781.2 AIN96682.1 - 1.9e-42 144.6 0.7 3.7e-42 143.7 0.5 1.4 1 0 0 1 1 1 1 ATP-binding dynein motor region D5 AAA_7 PF12775.2 AIN96682.1 - 1.3e-35 122.8 0.1 5e-35 120.9 0.0 2.0 2 0 0 2 2 2 1 P-loop containing dynein motor region D3 AAA_5 PF07728.9 AIN96682.1 - 1.5e-18 66.8 3.7 5.9e-06 26.0 0.0 6.3 6 1 0 6 6 6 4 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 AIN96682.1 - 4.5e-05 23.5 13.0 0.038 14.1 0.0 7.2 7 1 0 7 7 7 1 AAA domain AAA PF00004.24 AIN96682.1 - 0.00055 20.1 1.3 2 8.6 0.0 4.5 4 0 0 4 4 4 1 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.1 AIN96682.1 - 0.001 18.5 2.8 2.5 7.6 0.1 3.6 3 0 0 3 3 3 2 P-loop containing region of AAA domain AAA_17 PF13207.1 AIN96682.1 - 0.2 12.4 1.2 36 5.1 0.0 4.1 4 0 0 4 4 4 0 AAA domain RNA_helicase PF00910.17 AIN96682.1 - 0.25 11.5 0.2 21 5.3 0.0 3.9 4 0 0 4 4 4 0 RNA helicase Pkinase PF00069.20 AIN96683.1 - 5.5e-45 153.5 0.0 3.9e-44 150.7 0.0 2.1 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 AIN96683.1 - 5.2e-17 61.7 0.0 5.3e-16 58.4 0.0 2.1 2 0 0 2 2 2 1 Protein tyrosine kinase LST1 PF05083.8 AIN96684.1 - 0.1 12.5 0.8 0.34 10.9 0.3 2.0 2 0 0 2 2 2 0 LST-1 protein PQ-loop PF04193.9 AIN96685.1 - 6.6e-26 89.6 6.1 1.3e-12 47.0 0.2 2.5 2 0 0 2 2 2 2 PQ loop repeat Kinesin PF00225.18 AIN96686.1 - 1.7e-76 257.0 0.0 2.1e-76 256.8 0.0 1.1 1 0 0 1 1 1 1 Kinesin motor domain Myosin_tail_1 PF01576.14 AIN96687.1 - 0.021 12.5 44.7 0.26 8.9 5.8 2.2 1 1 1 2 2 2 0 Myosin tail Prefoldin_2 PF01920.15 AIN96687.1 - 0.025 14.3 35.4 0.6 9.8 0.3 6.0 1 1 6 7 7 7 0 Prefoldin subunit DUF1409 PF07197.7 AIN96687.1 - 0.078 13.0 11.4 4.6 7.3 0.3 4.6 1 1 2 3 3 3 0 Protein of unknown function (DUF1409) DNA_pol3_tau_5 PF12170.3 AIN96687.1 - 0.089 12.7 10.6 0.65 9.9 0.5 3.4 1 1 2 3 3 3 0 DNA polymerase III tau subunit V interacting with alpha Mnd1 PF03962.10 AIN96687.1 - 0.52 9.9 32.6 9 5.9 13.2 3.0 1 1 2 3 3 3 0 Mnd1 family TPR_MLP1_2 PF07926.7 AIN96687.1 - 0.94 9.2 34.9 1.9 8.2 6.5 3.6 2 1 1 3 3 3 0 TPR/MLP1/MLP2-like protein DUF4320 PF14208.1 AIN96687.1 - 1.6 8.7 10.4 5.9 6.8 0.5 3.5 1 1 3 4 4 4 0 Domain of unknown function (DUF4320) DUF1640 PF07798.6 AIN96687.1 - 1.7 8.6 16.9 9.6 6.2 11.6 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF1640) DUF3563 PF12086.3 AIN96687.1 - 2.4 7.9 10.0 7.1 6.4 0.1 4.4 4 1 1 5 5 5 0 Protein of unknown function (DUF3563) DUF342 PF03961.8 AIN96687.1 - 4.5 5.5 20.0 4.2 5.6 5.2 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF342) OSR1_C PF12202.3 AIN96687.1 - 4.9 6.8 6.0 79 3.0 0.1 3.4 3 0 0 3 3 3 0 Oxidative-stress-responsive kinase 1 C terminal DASH_Dad3 PF08656.5 AIN96687.1 - 10 5.9 10.0 18 5.0 4.2 2.9 1 1 0 2 2 2 0 DASH complex subunit Dad3 WD40 PF00400.27 AIN96688.1 - 0.002 17.9 0.2 0.002 17.9 0.2 5.6 6 0 0 6 6 6 2 WD domain, G-beta repeat CSD PF00313.17 AIN96689.1 - 5.9e-11 41.9 0.4 1.2e-05 25.0 0.0 3.8 4 0 0 4 4 4 2 'Cold-shock' DNA-binding domain S1-like PF14444.1 AIN96689.1 - 0.027 14.2 2.0 0.23 11.1 0.0 3.1 4 0 0 4 4 4 0 S1-like Tub PF01167.13 AIN96690.1 - 5.5e-29 100.8 0.0 4.9e-27 94.4 0.0 2.6 3 0 0 3 3 3 2 Tub family Enolase_C PF00113.17 AIN96692.1 - 9.4e-131 435.1 0.0 1.3e-130 434.7 0.0 1.1 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.11 AIN96692.1 - 7.4e-57 190.9 0.0 1.4e-56 190.0 0.0 1.5 1 0 0 1 1 1 1 Enolase, N-terminal domain MR_MLE_C PF13378.1 AIN96692.1 - 9.8e-05 22.2 0.4 0.00023 21.1 0.0 1.8 2 0 0 2 2 2 1 Enolase C-terminal domain-like MAAL_C PF07476.6 AIN96692.1 - 0.00013 20.9 0.1 0.00027 19.9 0.1 1.4 1 0 0 1 1 1 1 Methylaspartate ammonia-lyase C-terminus MR_MLE PF01188.16 AIN96692.1 - 0.076 13.5 0.0 0.22 12.0 0.0 1.9 1 1 0 1 1 1 0 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain FYVE PF01363.16 AIN96693.1 - 2e-15 56.3 20.7 4.1e-15 55.4 9.9 3.2 2 1 0 2 2 2 1 FYVE zinc finger Ras PF00071.17 AIN96693.1 - 1.9e-10 40.3 0.0 3.1e-10 39.6 0.0 1.3 1 0 0 1 1 1 1 Ras family Miro PF08477.8 AIN96693.1 - 1.3e-06 28.8 0.0 3.2e-06 27.6 0.0 1.6 1 0 0 1 1 1 1 Miro-like protein F-box-like PF12937.2 AIN96693.1 - 0.002 17.8 0.5 0.0054 16.4 0.0 1.9 2 0 0 2 2 2 1 F-box-like PAP_central PF04928.12 AIN96694.1 - 9.5e-81 270.3 0.0 1.3e-80 269.8 0.0 1.2 1 0 0 1 1 1 1 Poly(A) polymerase central domain PAP_RNA-bind PF04926.10 AIN96694.1 - 1.1e-26 93.2 0.0 1.8e-26 92.5 0.0 1.3 1 0 0 1 1 1 1 Poly(A) polymerase predicted RNA binding domain NTP_transf_2 PF01909.18 AIN96694.1 - 0.00074 19.7 0.0 0.0017 18.6 0.0 1.5 1 0 0 1 1 1 1 Nucleotidyltransferase domain DNA_pol_B_palm PF14792.1 AIN96694.1 - 0.014 15.4 0.0 0.032 14.2 0.0 1.6 1 0 0 1 1 1 0 DNA polymerase beta palm Carb_kinase PF01256.12 AIN96695.1 - 1.5e-50 171.7 5.2 2.5e-50 171.0 3.6 1.3 1 0 0 1 1 1 1 Carbohydrate kinase YjeF_N PF03853.10 AIN96695.1 - 7.5e-47 159.0 0.0 1.7e-46 157.9 0.0 1.6 1 0 0 1 1 1 1 YjeF-related protein N-terminus PSS PF03034.10 AIN96696.1 - 2e-110 368.6 12.4 3.2e-110 367.9 8.6 1.3 1 0 0 1 1 1 1 Phosphatidyl serine synthase DUF4381 PF14316.1 AIN96696.1 - 1.3 9.0 10.6 5.6 7.0 0.1 3.7 3 1 0 3 3 3 0 Domain of unknown function (DUF4381) NIF PF03031.13 AIN96697.1 - 1.3e-14 54.1 0.0 2.5e-06 27.2 0.0 2.1 2 0 0 2 2 2 2 NLI interacting factor-like phosphatase HAD_2 PF13419.1 AIN96697.1 - 0.012 15.8 0.1 2 8.6 0.0 2.4 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase BLOC1_2 PF10046.4 AIN96698.1 - 0.014 15.5 15.9 0.047 13.8 1.7 4.5 5 0 0 5 5 5 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 EcoEI_R_C PF08463.5 AIN96698.1 - 0.046 13.5 0.3 0.046 13.5 0.2 3.2 3 1 0 3 3 3 0 EcoEI R protein C-terminal COG2 PF06148.6 AIN96698.1 - 0.75 9.6 19.7 0.048 13.5 0.5 5.0 3 1 1 4 4 4 0 COG (conserved oligomeric Golgi) complex component, COG2 AAA_13 PF13166.1 AIN96698.1 - 4.2 5.7 17.6 2 6.7 3.0 3.0 2 1 1 3 3 3 0 AAA domain EMP24_GP25L PF01105.19 AIN96698.1 - 6.2 6.4 6.7 35 4.0 1.3 3.3 2 1 0 2 2 2 0 emp24/gp25L/p24 family/GOLD Fib_alpha PF08702.5 AIN96698.1 - 9.6 6.3 11.8 5.5 7.1 0.1 4.5 4 1 0 4 4 4 0 Fibrinogen alpha/beta chain family V_ATPase_I PF01496.14 AIN96698.1 - 9.7 3.9 17.0 1.9 6.2 0.5 3.1 2 1 1 3 3 3 0 V-type ATPase 116kDa subunit family HTH_37 PF13744.1 AIN96700.1 - 0.12 12.2 0.1 0.25 11.1 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain Pax7 PF12360.3 AIN96701.1 - 0.03 14.5 0.1 0.081 13.2 0.1 1.7 1 0 0 1 1 1 0 Paired box protein 7 Ribosomal_S27 PF01599.14 AIN96703.1 - 1.6e-20 72.6 3.7 3.4e-20 71.5 2.5 1.6 1 0 0 1 1 1 1 Ribosomal protein S27a ubiquitin PF00240.18 AIN96703.1 - 6.2e-07 28.7 0.1 4.1e-05 22.8 0.0 2.8 2 1 0 2 2 2 1 Ubiquitin family Rad60-SLD PF11976.3 AIN96703.1 - 3e-06 26.8 0.0 4.5e-05 23.0 0.0 2.3 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like IBR PF01485.16 AIN96703.1 - 0.0026 17.5 0.8 0.0041 16.9 0.6 1.3 1 0 0 1 1 1 1 IBR domain F420_oxidored PF03807.12 AIN96704.1 - 5e-06 26.8 0.0 1.6e-05 25.2 0.0 1.9 1 1 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent PDH PF02153.12 AIN96704.1 - 0.025 13.4 0.0 0.041 12.7 0.0 1.2 1 0 0 1 1 1 0 Prephenate dehydrogenase Reo_sigmaC PF04582.7 AIN96705.1 - 3.8 6.5 12.5 0.035 13.2 2.1 2.4 3 1 0 3 3 3 0 Reovirus sigma C capsid protein DUF919 PF06034.6 AIN96705.1 - 5.6 6.6 6.2 9.1 5.9 0.0 3.3 3 0 0 3 3 3 0 Nucleopolyhedrovirus protein of unknown function (DUF919) Pkinase PF00069.20 AIN96706.1 - 7.9e-63 212.0 0.0 2.5e-62 210.4 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AIN96706.1 - 2.2e-35 121.9 0.0 1.3e-32 112.9 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.18 AIN96706.1 - 0.059 13.0 0.0 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kinase-like PF14531.1 AIN96706.1 - 0.098 11.5 0.0 0.17 10.7 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Kdo PF06293.9 AIN96706.1 - 0.11 11.5 0.0 0.19 10.7 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family SHMT PF00464.14 AIN96708.1 - 2.2e-174 579.5 0.0 2.6e-174 579.2 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase DnaJ PF00226.26 AIN96709.1 - 1.3e-19 69.6 3.6 1.3e-19 69.6 2.5 2.0 2 0 0 2 2 2 1 DnaJ domain TPR_19 PF14559.1 AIN96709.1 - 1.7e-14 53.8 18.8 0.0023 18.2 0.0 6.4 4 2 2 6 6 6 5 Tetratricopeptide repeat TPR_16 PF13432.1 AIN96709.1 - 4.4e-14 52.6 15.5 7.3e-05 23.3 0.2 5.7 5 1 1 6 6 5 4 Tetratricopeptide repeat TPR_11 PF13414.1 AIN96709.1 - 1.1e-13 50.5 6.5 1.5e-06 27.7 0.1 5.3 5 1 0 5 5 5 3 TPR repeat TPR_14 PF13428.1 AIN96709.1 - 3.4e-06 27.1 22.5 2.5 8.9 0.0 8.0 6 3 4 10 10 9 2 Tetratricopeptide repeat TPR_9 PF13371.1 AIN96709.1 - 0.00036 20.3 12.5 0.12 12.2 0.1 5.0 3 2 2 5 5 5 2 Tetratricopeptide repeat TPR_6 PF13174.1 AIN96709.1 - 0.0023 18.2 9.7 72 4.1 0.1 8.2 9 0 0 9 9 9 0 Tetratricopeptide repeat TPR_8 PF13181.1 AIN96709.1 - 0.014 15.1 0.1 1.7 8.5 0.0 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat Alkyl_sulf_dimr PF14863.1 AIN96709.1 - 0.019 15.2 2.3 2.7 8.2 0.1 3.5 3 0 0 3 3 3 0 Alkyl sulfatase dimerisation TPR_2 PF07719.12 AIN96709.1 - 0.026 14.4 12.6 9.7 6.3 0.0 6.9 8 0 0 8 8 7 0 Tetratricopeptide repeat Mhr1 PF12829.2 AIN96709.1 - 0.027 14.2 0.5 1.3 8.9 0.4 2.8 2 0 0 2 2 2 0 Transcriptional regulation of mitochondrial recombination TPR_1 PF00515.23 AIN96709.1 - 0.052 13.1 6.1 16 5.3 0.0 5.1 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_12 PF13424.1 AIN96709.1 - 0.14 12.1 15.2 1.3 9.0 0.5 5.2 4 1 2 6 6 6 0 Tetratricopeptide repeat Uds1 PF15456.1 AIN96709.1 - 0.43 10.5 12.7 0.77 9.7 0.1 3.1 3 0 0 3 3 3 0 Up-regulated During Septation FA_desaturase PF00487.19 AIN96710.1 - 5.2e-40 137.4 9.4 5.2e-40 137.4 6.5 1.6 1 1 1 2 2 2 1 Fatty acid desaturase Cyt-b5 PF00173.23 AIN96710.1 - 1.6e-05 24.6 0.0 3.7e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain OPA3 PF07047.7 AIN96711.1 - 0.1 12.3 0.0 0.18 11.5 0.0 1.3 1 0 0 1 1 1 0 Optic atrophy 3 protein (OPA3) NAD_binding_5 PF07994.7 AIN96712.1 - 6e-107 357.5 0.0 6.9e-107 357.3 0.0 1.0 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase Inos-1-P_synth PF01658.12 AIN96712.1 - 1.1e-45 154.0 0.0 1.9e-45 153.2 0.0 1.4 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase tRNA-synt_1b PF00579.20 AIN96713.1 - 1.1e-53 182.3 0.0 8.3e-49 166.2 0.0 2.5 2 1 0 2 2 2 2 tRNA synthetases class I (W and Y) EMP24_GP25L PF01105.19 AIN96715.1 - 1.7e-20 73.5 0.0 2.1e-20 73.2 0.0 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD DUF2309 PF10070.4 AIN96716.1 - 0.029 12.4 0.0 0.035 12.2 0.0 1.0 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2309) Hpre_diP_synt_I PF07456.6 AIN96716.1 - 0.34 10.7 5.4 0.44 10.3 3.8 1.3 1 1 0 1 1 1 0 Heptaprenyl diphosphate synthase component I Pkinase PF00069.20 AIN96717.1 - 4.5e-67 225.9 0.0 6e-67 225.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AIN96717.1 - 1.3e-44 152.2 0.0 2e-44 151.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 AIN96717.1 - 5.1e-09 35.5 0.1 2.5e-07 29.9 0.0 2.1 2 0 0 2 2 2 2 Kinase-like WD40 PF00400.27 AIN96719.1 - 2.7e-07 30.2 15.2 0.13 12.1 0.0 7.4 8 0 0 8 8 8 3 WD domain, G-beta repeat IFT46_B_C PF12317.3 AIN96719.1 - 0.08 12.2 3.2 0.23 10.7 0.0 2.7 3 0 0 3 3 3 0 Intraflagellar transport complex B protein 46 C terminal Antimicrobial21 PF14861.1 AIN96720.1 - 0.0028 17.0 2.8 47 3.5 0.0 5.0 3 2 2 5 5 5 3 Plant antimicrobial peptide C2 PF00168.25 AIN96720.1 - 0.0047 16.7 0.0 0.28 11.0 0.0 2.5 2 0 0 2 2 2 1 C2 domain Vac14_Fig4_bd PF11916.3 AIN96721.1 - 4.1e-53 179.2 3.9 9.5e-53 178.0 2.7 1.6 1 0 0 1 1 1 1 Vacuolar protein 14 C-terminal Fig4p binding Vac14_Fab1_bd PF12755.2 AIN96721.1 - 1.6e-09 38.0 0.2 8.6e-08 32.4 0.0 3.0 3 0 0 3 3 3 1 Vacuolar 14 Fab1-binding region HEAT PF02985.17 AIN96721.1 - 0.016 15.2 0.0 0.016 15.2 0.0 4.3 4 0 0 4 4 4 0 HEAT repeat HEAT_2 PF13646.1 AIN96721.1 - 0.93 9.8 13.1 4.9 7.5 2.1 5.0 4 2 0 4 4 4 0 HEAT repeats MPC PF03650.8 AIN96722.1 - 1.5e-11 44.2 0.3 1.9e-11 43.9 0.2 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0041) GST_N_3 PF13417.1 AIN96724.1 - 1.8e-08 34.4 0.0 3.4e-08 33.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Glutaredoxin PF00462.19 AIN96724.1 - 5.2e-08 32.7 1.0 2.2e-07 30.7 0.3 2.1 2 0 0 2 2 2 1 Glutaredoxin GST_C_3 PF14497.1 AIN96724.1 - 0.001 19.4 0.0 0.0017 18.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 AIN96724.1 - 0.0032 17.4 0.0 0.0058 16.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Syja_N PF02383.13 AIN96725.1 - 5e-21 74.7 0.0 7.6e-21 74.1 0.0 1.2 1 0 0 1 1 1 1 SacI homology domain Histone PF00125.19 AIN96726.1 - 5.9e-13 48.7 0.5 7.2e-13 48.4 0.4 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 AIN96726.1 - 0.00045 20.2 0.4 0.00062 19.7 0.0 1.4 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TAF PF02969.12 AIN96726.1 - 0.00092 19.1 0.1 0.0015 18.4 0.1 1.4 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) Bromo_TP PF07524.8 AIN96726.1 - 0.0034 17.0 0.0 0.0042 16.7 0.0 1.2 1 0 0 1 1 1 1 Bromodomain associated TFIID-31kDa PF02291.10 AIN96726.1 - 0.0048 16.6 0.0 0.0048 16.6 0.0 1.2 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit GDA1_CD39 PF01150.12 AIN96728.1 - 2.3e-77 260.3 0.0 3.3e-77 259.8 0.0 1.2 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family Ppx-GppA PF02541.11 AIN96728.1 - 0.00011 21.4 0.0 0.00017 20.9 0.0 1.2 1 0 0 1 1 1 1 Ppx/GppA phosphatase family Lysine_decarbox PF03641.9 AIN96729.1 - 2.3e-23 82.4 0.0 4.5e-23 81.5 0.0 1.5 1 0 0 1 1 1 1 Possible lysine decarboxylase NAD_binding_1 PF00175.16 AIN96730.1 - 3.4e-26 91.9 0.0 5.6e-26 91.2 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 AIN96730.1 - 1.9e-23 82.4 0.0 2.9e-23 81.8 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.7 AIN96730.1 - 2.7e-06 27.3 0.0 0.00021 21.2 0.0 2.2 2 0 0 2 2 2 1 Ferric reductase NAD binding domain FAD_binding_9 PF08021.6 AIN96730.1 - 0.02 14.8 0.0 0.036 14.0 0.0 1.4 1 0 0 1 1 1 0 Siderophore-interacting FAD-binding domain MIF4G PF02854.14 AIN96731.1 - 8.4e-26 90.6 0.6 1.5e-25 89.9 0.4 1.4 1 0 0 1 1 1 1 MIF4G domain CRM1_C PF08767.6 AIN96731.1 - 3.6e-05 22.8 0.0 0.00012 21.1 0.0 1.9 1 0 0 1 1 1 1 CRM1 C terminal IMS PF00817.15 AIN96731.1 - 0.06 13.1 0.1 3.8 7.3 0.0 2.7 2 1 0 2 2 2 0 impB/mucB/samB family AAA_2 PF07724.9 AIN96734.1 - 8.3e-40 136.4 1.9 2.7e-31 108.7 0.2 2.8 1 1 1 2 2 2 2 AAA domain (Cdc48 subfamily) AAA PF00004.24 AIN96734.1 - 1.2e-13 51.4 0.1 5e-06 26.7 0.0 3.0 2 1 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 AIN96734.1 - 7.8e-09 35.3 0.4 2e-05 24.3 0.0 2.5 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 AIN96734.1 - 4e-06 26.9 0.0 0.00055 20.0 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 AIN96734.1 - 7e-06 26.8 0.1 3.7e-05 24.5 0.0 2.3 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.1 AIN96734.1 - 3.5e-05 23.8 0.1 0.00015 21.8 0.0 2.1 1 1 1 2 2 2 1 AAA ATPase domain AAA_18 PF13238.1 AIN96734.1 - 3.8e-05 23.9 0.3 0.00015 22.0 0.0 2.1 2 0 0 2 2 2 1 AAA domain ClpB_D2-small PF10431.4 AIN96734.1 - 5.9e-05 22.9 0.7 0.00023 20.9 0.0 2.3 2 0 0 2 2 2 1 C-terminal, D2-small domain, of ClpB protein Mg_chelatase PF01078.16 AIN96734.1 - 8.3e-05 21.8 0.1 0.002 17.3 0.0 2.8 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI MCM PF00493.18 AIN96734.1 - 0.00023 20.0 0.9 0.01 14.6 0.0 2.6 2 1 1 3 3 3 1 MCM2/3/5 family TIP49 PF06068.8 AIN96734.1 - 0.0004 19.2 0.0 0.0011 17.8 0.0 1.7 1 0 0 1 1 1 1 TIP49 C-terminus NTPase_1 PF03266.10 AIN96734.1 - 0.0015 18.3 1.2 0.4 10.3 0.0 2.6 2 0 0 2 2 2 1 NTPase AAA_14 PF13173.1 AIN96734.1 - 0.0018 18.1 0.0 2.1 8.2 0.0 2.5 2 0 0 2 2 2 2 AAA domain RuvB_N PF05496.7 AIN96734.1 - 0.0022 17.0 0.1 0.019 14.0 0.0 2.3 2 1 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus Zeta_toxin PF06414.7 AIN96734.1 - 0.004 16.2 0.0 0.0082 15.2 0.0 1.6 1 0 0 1 1 1 1 Zeta toxin DEAD PF00270.24 AIN96734.1 - 0.004 16.6 0.0 0.31 10.5 0.0 2.5 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_33 PF13671.1 AIN96734.1 - 0.0056 16.5 0.1 0.017 15.0 0.0 1.9 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.12 AIN96734.1 - 0.014 14.7 0.0 0.033 13.5 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_28 PF13521.1 AIN96734.1 - 0.014 15.3 0.1 0.087 12.7 0.0 2.3 2 1 1 3 3 3 0 AAA domain Sigma54_activat PF00158.21 AIN96734.1 - 0.017 14.6 0.0 0.053 12.9 0.0 1.8 2 0 0 2 2 1 0 Sigma-54 interaction domain CPT PF07931.7 AIN96734.1 - 0.024 14.2 0.3 0.2 11.2 0.0 2.5 3 0 0 3 3 3 0 Chloramphenicol phosphotransferase-like protein ABC_tran PF00005.22 AIN96734.1 - 0.03 14.6 0.1 0.069 13.4 0.1 1.6 1 0 0 1 1 1 0 ABC transporter UPF0079 PF02367.12 AIN96734.1 - 0.04 13.5 0.0 0.29 10.7 0.0 2.2 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 DUF258 PF03193.11 AIN96734.1 - 0.046 12.9 0.0 0.079 12.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 NACHT PF05729.7 AIN96734.1 - 0.072 12.7 0.0 2.5 7.7 0.0 2.6 2 1 0 2 2 2 0 NACHT domain ATP-synt_ab PF00006.20 AIN96734.1 - 0.087 12.3 0.1 0.21 11.0 0.0 1.6 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain RNA_helicase PF00910.17 AIN96734.1 - 0.11 12.7 0.0 0.71 10.0 0.0 2.3 2 1 0 2 2 2 0 RNA helicase FMO-like PF00743.14 AIN96735.1 - 5.5e-27 94.1 0.1 1.4e-22 79.6 0.1 2.1 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 AIN96735.1 - 3.8e-17 63.0 0.1 1.3e-16 61.2 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 AIN96735.1 - 1.7e-09 37.8 0.0 1.4e-08 34.8 0.0 2.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 AIN96735.1 - 9.3e-09 34.6 0.9 6.1e-07 28.6 0.3 2.2 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.1 AIN96735.1 - 7.2e-06 25.9 0.0 4.5e-05 23.3 0.0 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 AIN96735.1 - 0.00037 20.8 0.0 0.67 10.3 0.0 3.2 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 AIN96735.1 - 0.00059 19.6 0.2 0.0026 17.5 0.0 2.3 2 1 0 2 2 2 1 FAD-NAD(P)-binding IlvN PF07991.7 AIN96735.1 - 0.0079 15.5 0.1 1.9 7.8 0.0 2.6 3 0 0 3 3 3 1 Acetohydroxy acid isomeroreductase, catalytic domain HI0933_like PF03486.9 AIN96735.1 - 0.0082 14.6 0.1 0.012 14.0 0.1 1.2 1 0 0 1 1 1 1 HI0933-like protein Lycopene_cycl PF05834.7 AIN96735.1 - 0.029 13.2 0.0 0.055 12.3 0.0 1.5 1 1 0 1 1 1 0 Lycopene cyclase protein GIDA PF01134.17 AIN96735.1 - 0.071 11.9 0.8 1.4 7.6 0.0 2.1 2 0 0 2 2 2 0 Glucose inhibited division protein A NAD_binding_7 PF13241.1 AIN96735.1 - 0.075 13.2 0.1 4.3 7.6 0.0 3.0 3 0 0 3 3 3 0 Putative NAD(P)-binding Oxidored_nitro PF00148.14 AIN96735.1 - 0.11 11.1 0.0 0.2 10.2 0.0 1.3 1 0 0 1 1 1 0 Nitrogenase component 1 type Oxidoreductase Mito_carr PF00153.22 AIN96737.1 - 1.2e-45 153.1 0.5 1.4e-17 63.1 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein DEAD PF00270.24 AIN96738.1 - 1.1e-41 142.0 0.2 2.3e-41 141.1 0.1 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 AIN96738.1 - 2.4e-21 75.3 0.1 1.1e-20 73.2 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain zf-CCCH PF00642.19 AIN96739.1 - 4e-08 32.7 5.5 4e-08 32.7 3.8 2.3 2 0 0 2 2 2 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) oligo_HPY PF08352.7 AIN96739.1 - 0.011 16.0 3.6 0.49 10.7 0.4 2.6 2 0 0 2 2 2 0 Oligopeptide/dipeptide transporter, C-terminal region zf-CCCH PF00642.19 AIN96740.1 - 6.6e-07 28.8 4.2 1.1e-06 28.1 2.9 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.1 AIN96740.1 - 0.14 12.2 3.3 0.41 10.7 2.3 1.9 1 1 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type PP2C PF00481.16 AIN96741.1 - 3.4e-66 223.2 0.5 3.4e-66 223.2 0.3 1.5 2 0 0 2 2 2 1 Protein phosphatase 2C PP2C_2 PF13672.1 AIN96741.1 - 4.1e-07 29.6 1.9 8.4e-06 25.3 0.0 2.4 2 1 0 2 2 2 1 Protein phosphatase 2C DUF3276 PF11680.3 AIN96741.1 - 0.0033 17.2 2.2 0.0089 15.8 1.5 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3276) Pkinase PF00069.20 AIN96742.1 - 4.4e-46 157.1 0.0 6.4e-46 156.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AIN96742.1 - 4.1e-15 55.5 0.0 6.6e-15 54.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 AIN96742.1 - 7.6e-05 22.5 0.1 0.00078 19.2 0.0 2.4 2 1 0 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 AIN96742.1 - 0.0041 16.7 0.0 0.008 15.7 0.0 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase PIP49_C PF12260.3 AIN96742.1 - 0.084 12.2 0.0 0.15 11.4 0.0 1.3 1 0 0 1 1 1 0 Protein-kinase domain of FAM69 SlyX PF04102.7 AIN96743.1 - 0.054 13.8 0.7 1.3 9.4 0.0 2.9 2 0 0 2 2 2 0 SlyX CENP-Q PF13094.1 AIN96743.1 - 0.43 10.6 6.7 1.8 8.5 0.1 3.1 3 0 0 3 3 3 0 CENP-Q, a CENPA-CAD centromere complex subunit DUF3847 PF12958.2 AIN96743.1 - 1 9.1 4.5 5.2 6.9 0.1 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3847) PTRF_SDPR PF15237.1 AIN96743.1 - 2.7 7.3 7.1 0.81 9.0 0.1 3.0 4 0 0 4 4 4 0 PTRF/SDPR family Cyt-b5 PF00173.23 AIN96744.1 - 3e-06 26.9 0.0 4.1e-06 26.4 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Ribosomal_L13 PF00572.13 AIN96746.1 - 1.5e-22 80.0 0.2 3.1e-22 78.9 0.1 1.6 1 0 0 1 1 1 1 Ribosomal protein L13 DUF4455 PF14643.1 AIN96746.1 - 0.019 13.6 2.6 0.025 13.2 1.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4455) alpha-hel2 PF14456.1 AIN96746.1 - 0.36 9.5 2.1 0.53 8.9 1.4 1.2 1 0 0 1 1 1 0 Alpha-helical domain 2 Metallophos PF00149.23 AIN96748.1 - 9.7e-29 100.1 0.0 1.4e-28 99.6 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Macin PF14865.1 AIN96748.1 - 0.16 12.0 0.3 4.1 7.5 0.0 2.3 2 0 0 2 2 2 0 Macin WD40 PF00400.27 AIN96750.1 - 2.4e-13 49.3 4.1 2.3e-06 27.2 0.0 5.3 5 0 0 5 5 5 5 WD domain, G-beta repeat tRNA-synt_2 PF00152.15 AIN96751.1 - 3.7e-88 295.5 0.1 6.1e-88 294.8 0.0 1.4 2 0 0 2 2 2 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 AIN96751.1 - 2.7e-11 43.1 0.1 5.9e-11 42.0 0.0 1.6 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.15 AIN96751.1 - 2.7e-07 30.0 0.0 0.002 17.3 0.0 2.7 3 0 0 3 3 3 2 tRNA synthetases class II core domain (F) tRNA-synt_2b PF00587.20 AIN96751.1 - 0.0013 18.3 0.1 0.11 12.0 0.0 3.0 3 0 0 3 3 3 1 tRNA synthetase class II core domain (G, H, P, S and T) DUF972 PF06156.8 AIN96751.1 - 0.059 13.7 0.5 0.12 12.7 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF972) Cellulose_synt PF03552.9 AIN96754.1 - 0.057 11.7 0.4 0.077 11.2 0.3 1.1 1 0 0 1 1 1 0 Cellulose synthase RPA_C PF08784.6 AIN96755.1 - 2.2e-15 56.9 2.6 2.3e-15 56.8 0.7 1.9 2 0 0 2 2 2 1 Replication protein A C terminal tRNA_anti-codon PF01336.20 AIN96755.1 - 3.7e-08 33.1 0.1 6.4e-08 32.3 0.0 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain PPR_2 PF13041.1 AIN96756.1 - 8.4e-07 28.8 0.6 0.045 13.7 0.0 2.4 2 0 0 2 2 2 2 PPR repeat family PPR_3 PF13812.1 AIN96756.1 - 0.0028 17.8 0.0 4.3 7.8 0.0 2.7 2 0 0 2 2 2 2 Pentatricopeptide repeat domain RPM2 PF08579.6 AIN96756.1 - 0.01 15.9 0.0 0.016 15.3 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial ribonuclease P subunit (RPM2) Ecotin PF03974.8 AIN96758.1 - 8.4e-40 135.4 0.0 1e-39 135.1 0.0 1.0 1 0 0 1 1 1 1 Ecotin Abhydrolase_3 PF07859.8 AIN96760.1 - 1e-12 48.0 0.1 2.7e-12 46.7 0.0 1.7 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 AIN96760.1 - 1.8e-10 40.7 0.0 4.5e-10 39.4 0.0 1.7 1 0 0 1 1 1 1 Alpha/beta hydrolase family COesterase PF00135.23 AIN96760.1 - 4.1e-10 38.9 0.0 8.4e-10 37.9 0.0 1.5 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_6 PF12697.2 AIN96760.1 - 2.6e-07 30.7 0.0 5.9e-07 29.6 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 AIN96760.1 - 4.6e-06 25.9 0.9 0.0048 16.1 0.1 3.3 3 1 0 3 3 3 2 Prolyl oligopeptidase family DUF4566 PF15130.1 AIN96760.1 - 0.15 11.1 0.0 0.3 10.2 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4566) Chlorophyllase2 PF12740.2 AIN96760.1 - 0.18 10.6 0.0 0.3 9.9 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase enzyme Abhydrolase_3 PF07859.8 AIN96761.1 - 2e-11 43.8 0.1 3.8e-11 42.9 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 AIN96761.1 - 4.9e-10 39.3 0.0 2.5e-09 37.0 0.0 2.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family COesterase PF00135.23 AIN96761.1 - 6.4e-10 38.3 0.0 1e-09 37.7 0.0 1.2 1 0 0 1 1 1 1 Carboxylesterase family Peptidase_S9 PF00326.16 AIN96761.1 - 1.7e-06 27.4 0.1 0.0029 16.8 0.1 2.7 2 1 0 2 2 2 2 Prolyl oligopeptidase family Chlorophyllase2 PF12740.2 AIN96761.1 - 0.00033 19.6 0.0 0.00067 18.6 0.0 1.4 1 0 0 1 1 1 1 Chlorophyllase enzyme MSP1_C PF07462.6 AIN96761.1 - 3.2 6.0 3.3 5.5 5.2 2.3 1.2 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus 7tm_3 PF00003.17 AIN96762.1 - 0.025 13.9 2.5 0.028 13.7 0.5 1.9 2 0 0 2 2 2 0 7 transmembrane sweet-taste receptor of 3 GCPR PseudoU_synth_2 PF00849.17 AIN96763.1 - 1.4e-16 60.7 4.3 3.6e-07 30.1 0.7 3.6 3 1 0 3 3 3 3 RNA pseudouridylate synthase Ribosomal_60s PF00428.14 AIN96764.1 - 8.4e-19 67.7 13.7 1e-18 67.5 9.5 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein Arg_repressor_C PF02863.13 AIN96764.1 - 0.0043 16.5 0.2 0.0078 15.6 0.2 1.4 1 0 0 1 1 1 1 Arginine repressor, C-terminal domain 3HBOH PF10605.4 AIN96764.1 - 0.041 11.9 5.8 0.043 11.9 4.1 1.0 1 0 0 1 1 1 0 3HB-oligomer hydrolase (3HBOH) Asparaginase PF00710.15 AIN96765.1 - 4.6e-67 226.1 0.0 8.2e-61 205.5 0.0 2.0 2 0 0 2 2 2 2 Asparaginase PPR_2 PF13041.1 AIN96767.1 - 0.016 15.1 0.0 1.2 9.1 0.0 2.6 1 1 1 2 2 2 0 PPR repeat family AAA PF00004.24 AIN96771.1 - 7.7e-39 132.9 0.0 1.4e-38 132.0 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.5 AIN96771.1 - 1.8e-05 24.5 0.0 4.6e-05 23.2 0.0 1.7 1 0 0 1 1 1 1 Vps4 C terminal oligomerisation domain RuvB_N PF05496.7 AIN96771.1 - 1.8e-05 23.9 0.0 3.7e-05 22.8 0.0 1.5 1 1 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_5 PF07728.9 AIN96771.1 - 2.3e-05 24.1 0.1 0.00018 21.2 0.1 2.5 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 AIN96771.1 - 6.6e-05 23.0 0.2 0.0022 18.1 0.0 2.9 1 1 1 2 2 2 1 AAA domain AAA_16 PF13191.1 AIN96771.1 - 0.00012 22.1 0.9 0.013 15.5 0.0 3.5 2 1 0 2 2 2 1 AAA ATPase domain AAA_19 PF13245.1 AIN96771.1 - 0.00015 21.4 4.1 0.0019 17.9 0.0 3.6 3 1 0 3 3 3 1 Part of AAA domain AAA_17 PF13207.1 AIN96771.1 - 0.00016 22.4 0.0 0.00041 21.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.1 AIN96771.1 - 0.00038 19.9 0.2 0.087 12.2 0.0 2.5 1 1 1 2 2 2 1 AAA domain IstB_IS21 PF01695.12 AIN96771.1 - 0.00089 18.7 0.0 0.0017 17.8 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein TIP49 PF06068.8 AIN96771.1 - 0.0028 16.4 0.0 0.0044 15.7 0.0 1.3 1 0 0 1 1 1 1 TIP49 C-terminus AAA_2 PF07724.9 AIN96771.1 - 0.003 17.4 0.0 0.0052 16.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) Mg_chelatase PF01078.16 AIN96771.1 - 0.0041 16.3 0.1 0.011 14.9 0.1 1.7 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_33 PF13671.1 AIN96771.1 - 0.01 15.7 0.2 0.046 13.6 0.0 2.2 2 1 0 2 2 1 1 AAA domain DUF815 PF05673.8 AIN96771.1 - 0.028 13.3 0.0 0.057 12.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Zeta_toxin PF06414.7 AIN96771.1 - 0.029 13.4 0.0 0.056 12.5 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_14 PF13173.1 AIN96771.1 - 0.041 13.7 0.0 0.091 12.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 AIN96771.1 - 0.067 13.5 0.0 0.15 12.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 AIN96771.1 - 0.095 12.3 0.0 0.49 10.0 0.0 2.1 1 1 1 2 2 2 0 NACHT domain AAA_11 PF13086.1 AIN96771.1 - 0.095 12.2 0.0 0.16 11.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain Parvo_NS1 PF01057.12 AIN96771.1 - 0.1 11.4 0.0 0.17 10.7 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 RNA_helicase PF00910.17 AIN96771.1 - 0.12 12.5 0.0 0.24 11.6 0.0 1.4 1 0 0 1 1 1 0 RNA helicase Ecotin PF03974.8 AIN96772.1 - 1.7e-42 144.1 0.0 1.9e-42 143.9 0.0 1.0 1 0 0 1 1 1 1 Ecotin Ecotin PF03974.8 AIN96773.1 - 7.3e-35 119.4 0.1 1.1e-34 118.8 0.0 1.3 1 0 0 1 1 1 1 Ecotin WXG100 PF06013.7 AIN96775.1 - 0.34 10.9 14.0 1.7 8.6 0.4 4.8 3 1 0 3 3 3 0 Proteins of 100 residues with WXG Pox_A_type_inc PF04508.7 AIN96775.1 - 7.5 6.6 9.3 7.3 6.6 0.0 4.4 4 0 0 4 4 4 0 Viral A-type inclusion protein repeat DUF3587 PF12132.3 AIN96776.1 - 0.13 11.4 0.4 0.23 10.6 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3587) NBP1 PF08537.5 AIN96777.1 - 0.026 13.7 0.0 0.026 13.7 0.0 2.6 3 0 0 3 3 3 0 Fungal Nap binding protein NBP1 TcdB_N PF12918.2 AIN96777.1 - 0.035 14.1 0.0 0.078 13.0 0.0 1.6 1 0 0 1 1 1 0 TcdB toxin N-terminal helical domain RPT PF13446.1 AIN96777.1 - 0.042 13.2 0.0 0.52 9.7 0.0 2.7 2 0 0 2 2 2 0 A repeated domain in UCH-protein IncA PF04156.9 AIN96777.1 - 0.77 9.3 18.7 2.7 7.5 8.0 2.9 3 0 0 3 3 3 0 IncA protein DUF1664 PF07889.7 AIN96777.1 - 0.96 9.2 5.9 3.5 7.4 0.7 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Lebercilin PF15619.1 AIN96777.1 - 1.1 8.6 26.1 2.3 7.6 5.9 4.7 4 1 1 5 5 5 0 Ciliary protein causing Leber congenital amaurosis disease DUF641 PF04859.7 AIN96777.1 - 1.9 8.2 13.2 0.088 12.5 4.1 2.6 2 1 0 2 2 2 0 Plant protein of unknown function (DUF641) Reo_sigmaC PF04582.7 AIN96777.1 - 3.2 6.8 8.7 0.38 9.8 0.5 2.5 2 1 0 2 2 2 0 Reovirus sigma C capsid protein RasGAP_C PF03836.10 AIN96777.1 - 4.7 6.8 11.5 0.34 10.6 2.6 2.7 3 0 0 3 3 3 0 RasGAP C-terminus SPC22 PF04573.7 AIN96779.1 - 3.1e-09 36.3 0.2 2.5e-06 26.8 0.0 3.0 3 0 0 3 3 3 3 Signal peptidase subunit Sensor PF13796.1 AIN96782.1 - 3.4 7.2 5.5 12 5.4 0.6 2.7 3 0 0 3 3 3 0 Putative sensor CRAL_TRIO PF00650.15 AIN96783.1 - 8.1e-18 64.4 0.0 3.4e-15 55.8 0.0 2.8 2 1 0 2 2 2 2 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 AIN96783.1 - 0.11 12.7 0.2 0.89 9.7 0.0 2.8 4 0 0 4 4 4 0 CRAL/TRIO, N-terminal domain ESR1_C PF12743.2 AIN96784.1 - 0.00064 19.2 1.7 0.00064 19.2 1.2 2.2 2 0 0 2 2 2 1 Oestrogen-type nuclear receptor final C-terminal CompInhib_SCIN PF11546.3 AIN96784.1 - 0.11 12.3 0.0 0.23 11.3 0.0 1.4 1 0 0 1 1 1 0 Staphylococcal complement inhibitor SCIN DUF842 PF05811.8 AIN96785.1 - 0.016 14.6 1.9 0.043 13.2 1.3 1.6 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF842) OmpH PF03938.9 AIN96785.1 - 0.36 10.7 8.0 1.7 8.5 0.2 2.3 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) Kelch_4 PF13418.1 AIN96786.1 - 3.7e-24 84.2 4.8 5.4e-07 29.2 0.0 6.8 6 0 0 6 6 6 6 Galactose oxidase, central domain Kelch_5 PF13854.1 AIN96786.1 - 2.6e-18 65.5 1.0 0.0004 20.2 0.1 5.4 5 0 0 5 5 5 4 Kelch motif Kelch_3 PF13415.1 AIN96786.1 - 1.7e-17 63.0 11.8 0.00014 21.9 0.0 6.9 6 0 0 6 6 6 5 Galactose oxidase, central domain Kelch_6 PF13964.1 AIN96786.1 - 3.7e-14 52.1 4.2 1.4e-06 28.1 0.1 4.1 4 0 0 4 4 4 2 Kelch motif Kelch_2 PF07646.10 AIN96786.1 - 4.5e-13 48.3 3.4 0.00019 21.0 0.0 4.1 3 0 0 3 3 3 3 Kelch motif Kelch_1 PF01344.20 AIN96786.1 - 4.8e-09 35.6 3.8 0.0021 17.5 0.1 4.0 4 0 0 4 4 4 2 Kelch motif Ipi1_N PF12333.3 AIN96789.1 - 1.4e-07 31.3 2.9 0.00011 22.1 0.2 3.6 3 0 0 3 3 3 2 Rix1 complex component involved in 60S ribosome maturation HEAT PF02985.17 AIN96789.1 - 0.027 14.5 0.5 1.1 9.5 0.1 3.1 2 0 0 2 2 2 0 HEAT repeat V-ATPase_H_C PF11698.3 AIN96789.1 - 0.18 11.7 0.0 0.36 10.7 0.0 1.4 1 0 0 1 1 1 0 V-ATPase subunit H Cmc1 PF08583.5 AIN96790.1 - 0.00051 19.7 1.4 0.00051 19.7 1.0 2.2 3 0 0 3 3 3 1 Cytochrome c oxidase biogenesis protein Cmc1 like TfoX_N PF04993.8 AIN96790.1 - 0.22 11.4 0.9 0.58 10.0 0.1 2.1 2 0 0 2 2 2 0 TfoX N-terminal domain UPF0203 PF05254.7 AIN96790.1 - 0.69 9.7 7.3 0.13 12.1 0.9 2.7 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0203) tRNA_SAD PF07973.9 AIN96791.1 - 0.00037 20.3 0.1 0.0089 15.8 0.1 2.6 2 0 0 2 2 2 1 Threonyl and Alanyl tRNA synthetase second additional domain tRNA-synt_2c PF01411.14 AIN96791.1 - 0.014 13.6 0.0 0.02 13.1 0.0 1.2 1 0 0 1 1 1 0 tRNA synthetases class II (A) F-box-like_2 PF13013.1 AIN96792.1 - 0.064 12.9 0.0 0.15 11.7 0.0 1.6 1 0 0 1 1 1 0 F-box-like domain PPR_3 PF13812.1 AIN96793.1 - 0.3 11.4 8.5 51 4.5 0.0 6.1 5 0 0 5 5 5 0 Pentatricopeptide repeat domain FAD_binding_3 PF01494.14 AIN96794.1 - 3.4e-06 26.3 0.4 2.6e-05 23.4 0.3 2.2 1 1 0 1 1 1 1 FAD binding domain Methyltransf_16 PF10294.4 AIN96795.1 - 1.9e-09 37.2 0.0 6.9e-06 25.6 0.0 2.1 2 0 0 2 2 2 2 Putative methyltransferase Methyltransf_18 PF12847.2 AIN96795.1 - 4.9e-05 23.8 0.1 8.3e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PTCRA PF15028.1 AIN96795.1 - 0.0054 16.3 0.1 0.014 14.9 0.1 1.7 1 0 0 1 1 1 1 Pre-T-cell antigen receptor Methyltransf_25 PF13649.1 AIN96795.1 - 0.032 14.5 0.1 0.061 13.6 0.1 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_26 PF13659.1 AIN96795.1 - 0.06 13.3 0.2 0.1 12.6 0.1 1.4 1 0 0 1 1 1 0 Methyltransferase domain ABC_tran PF00005.22 AIN96796.1 - 2.4e-55 186.5 0.0 7.4e-29 100.7 0.0 3.3 3 0 0 3 3 3 2 ABC transporter ABC2_membrane_3 PF12698.2 AIN96796.1 - 4.2e-42 144.4 56.6 3e-32 112.0 15.0 3.0 4 0 0 4 4 4 2 ABC-2 family transporter protein AAA_21 PF13304.1 AIN96796.1 - 2.1e-24 86.9 0.0 2.7e-09 37.3 0.0 4.3 4 0 0 4 4 4 4 AAA domain SMC_N PF02463.14 AIN96796.1 - 4.6e-08 32.5 0.0 0.51 9.5 0.0 4.2 4 0 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 AIN96796.1 - 1.3e-06 27.8 0.5 0.0014 18.1 0.0 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.1 AIN96796.1 - 6.5e-05 23.3 0.7 0.018 15.3 0.0 2.3 2 0 0 2 2 2 1 AAA domain DUF258 PF03193.11 AIN96796.1 - 0.00048 19.3 0.0 0.8 8.8 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_15 PF13175.1 AIN96796.1 - 0.00055 19.1 0.0 2.6 7.0 0.0 3.7 4 0 0 4 4 4 1 AAA ATPase domain AAA_10 PF12846.2 AIN96796.1 - 0.011 15.1 0.0 0.41 10.0 0.0 2.6 3 0 0 3 3 3 0 AAA-like domain Zeta_toxin PF06414.7 AIN96796.1 - 0.012 14.7 0.0 13 4.8 0.0 3.2 3 0 0 3 3 3 0 Zeta toxin DUF4162 PF13732.1 AIN96796.1 - 0.014 15.9 0.0 0.25 11.8 0.0 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4162) SbcCD_C PF13558.1 AIN96796.1 - 0.023 14.5 0.0 1 9.3 0.0 3.0 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit IstB_IS21 PF01695.12 AIN96796.1 - 0.039 13.3 0.0 1.8 7.9 0.0 3.0 3 0 0 3 3 3 0 IstB-like ATP binding protein AAA_22 PF13401.1 AIN96796.1 - 0.054 13.6 0.1 1.1 9.4 0.0 3.0 3 0 0 3 3 3 0 AAA domain Mg_chelatase PF01078.16 AIN96796.1 - 0.055 12.6 0.0 1.9 7.6 0.0 3.2 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI AAA_25 PF13481.1 AIN96796.1 - 0.068 12.5 0.1 1.1 8.6 0.0 2.5 2 0 0 2 2 2 0 AAA domain Gtr1_RagA PF04670.7 AIN96796.1 - 0.17 10.9 0.2 4.1 6.4 0.0 2.2 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region Miro PF08477.8 AIN96796.1 - 0.27 11.7 0.0 40 4.7 0.0 2.9 2 0 0 2 2 2 0 Miro-like protein G-alpha PF00503.15 AIN96796.1 - 0.63 8.6 0.0 1.3 7.6 0.0 1.4 1 0 0 1 1 1 0 G-protein alpha subunit AAA_13 PF13166.1 AIN96796.1 - 1.5 7.1 0.0 22 3.3 0.0 2.2 3 0 0 3 3 3 0 AAA domain DUF2871 PF11070.3 AIN96798.1 - 1.3e-48 164.4 12.0 1.5e-48 164.2 8.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2871) Plant_vir_prot PF01307.12 AIN96798.1 - 0.035 13.8 0.1 1.5 8.5 0.0 2.2 2 0 0 2 2 2 0 Plant viral movement protein TrbC PF04956.8 AIN96798.1 - 0.054 13.5 2.7 0.17 11.9 1.9 1.8 1 1 0 1 1 1 0 TrbC/VIRB2 family DUF4386 PF14329.1 AIN96798.1 - 0.13 11.7 2.7 0.16 11.4 1.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4386) Pkinase PF00069.20 AIN96799.1 - 1.1e-26 93.5 0.0 1.7e-26 92.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AIN96799.1 - 4.1e-11 42.4 0.0 6.4e-11 41.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 AIN96799.1 - 0.0001 21.3 0.0 0.00017 20.6 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 AIN96799.1 - 0.098 12.3 0.0 4.5 6.9 0.0 2.4 1 1 1 2 2 2 0 Phosphotransferase enzyme family PAT1 PF09770.4 AIN96799.1 - 2.2 6.4 28.3 3 5.9 19.6 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Pex16 PF08610.5 AIN96803.1 - 2.9e-23 82.4 0.2 9.1e-20 70.9 0.0 2.6 2 1 0 2 2 2 2 Peroxisomal membrane protein (Pex16) DPM2 PF07297.7 AIN96804.1 - 1.2e-16 60.7 0.7 2e-16 60.0 0.5 1.4 1 0 0 1 1 1 1 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) MFS_1_like PF12832.2 AIN96804.1 - 0.15 11.9 0.9 0.22 11.3 0.6 1.3 1 0 0 1 1 1 0 MFS_1 like family GDI PF00996.13 AIN96805.1 - 2.8e-33 114.9 0.0 4.5e-20 71.3 0.0 2.1 2 0 0 2 2 2 2 GDP dissociation inhibitor Methyltransf_16 PF10294.4 AIN96805.1 - 7.9e-12 44.9 0.0 2.6e-05 23.7 0.0 2.3 2 0 0 2 2 2 2 Putative methyltransferase MTS PF05175.9 AIN96805.1 - 0.016 14.5 0.1 0.9 8.8 0.0 2.5 1 1 1 2 2 2 0 Methyltransferase small domain Methyltransf_18 PF12847.2 AIN96805.1 - 0.032 14.8 0.1 0.12 12.9 0.1 2.0 1 0 0 1 1 1 0 Methyltransferase domain UPF0060 PF02694.10 AIN96805.1 - 0.072 13.1 0.1 0.21 11.6 0.1 1.7 1 0 0 1 1 1 0 Uncharacterised BCR, YnfA/UPF0060 family Nop14 PF04147.7 AIN96809.1 - 1.3 6.8 5.9 1.8 6.4 4.1 1.2 1 0 0 1 1 1 0 Nop14-like family MFS_1 PF07690.11 AIN96810.1 - 1.6e-15 56.6 32.2 5.8e-12 44.9 9.0 2.2 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 AIN96810.1 - 1.6e-07 30.2 5.9 1.6e-07 30.2 4.1 2.7 2 1 1 3 3 3 2 Sugar (and other) transporter DUF1228 PF06779.9 AIN96810.1 - 0.00014 21.7 3.5 0.0019 18.1 0.9 3.2 2 0 0 2 2 2 1 Protein of unknown function (DUF1228) Inositol_P PF00459.20 AIN96811.1 - 7.3e-43 146.8 1.6 4.6e-21 75.3 0.1 2.2 2 0 0 2 2 2 2 Inositol monophosphatase family Kdo_hydroxy PF11004.3 AIN96811.1 - 0.088 11.7 0.0 0.14 11.0 0.0 1.3 1 0 0 1 1 1 0 3-deoxy-D-manno-oct-2-ulosonic acid (Kdo) hydroxylase ABC2_membrane PF01061.19 AIN96812.1 - 6.2e-37 126.8 18.9 6.2e-37 126.8 13.1 1.5 2 0 0 2 2 2 1 ABC-2 type transporter ABC_tran PF00005.22 AIN96812.1 - 6e-19 68.7 0.0 9.7e-19 68.0 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 AIN96812.1 - 0.00035 20.6 0.2 0.22 11.4 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 AIN96812.1 - 0.00055 19.9 0.0 0.0012 18.9 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain DUF258 PF03193.11 AIN96812.1 - 0.0024 17.0 0.0 0.0042 16.2 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_29 PF13555.1 AIN96812.1 - 0.0062 16.0 0.2 0.014 14.9 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_22 PF13401.1 AIN96812.1 - 0.0064 16.6 0.0 0.014 15.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_23 PF13476.1 AIN96812.1 - 0.021 15.1 0.0 0.035 14.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain PRK PF00485.13 AIN96812.1 - 0.034 13.7 0.0 0.055 13.0 0.0 1.3 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family NB-ARC PF00931.17 AIN96812.1 - 0.034 12.9 0.0 0.056 12.3 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain AAA_14 PF13173.1 AIN96812.1 - 0.053 13.4 0.0 0.14 12.0 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.1 AIN96812.1 - 0.055 13.0 0.5 0.11 12.0 0.4 1.4 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 AIN96812.1 - 0.058 13.0 0.0 0.13 11.9 0.0 1.6 1 0 0 1 1 1 0 NACHT domain AAA_19 PF13245.1 AIN96812.1 - 0.06 13.1 0.0 0.16 11.7 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain RNA_helicase PF00910.17 AIN96812.1 - 0.061 13.5 0.0 0.43 10.7 0.0 2.1 2 0 0 2 2 2 0 RNA helicase AAA_15 PF13175.1 AIN96812.1 - 0.061 12.3 0.0 1.6 7.6 0.0 2.0 2 0 0 2 2 2 0 AAA ATPase domain AAA_10 PF12846.2 AIN96812.1 - 0.064 12.6 0.1 0.13 11.6 0.1 1.5 1 0 0 1 1 1 0 AAA-like domain UPF0079 PF02367.12 AIN96812.1 - 0.065 12.8 0.1 0.18 11.4 0.0 1.7 2 0 0 2 2 1 0 Uncharacterised P-loop hydrolase UPF0079 AAA_25 PF13481.1 AIN96812.1 - 0.09 12.1 0.0 0.19 11.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain SMC_N PF02463.14 AIN96812.1 - 0.11 11.7 0.0 9.3 5.4 0.0 2.2 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain Mg_chelatase PF01078.16 AIN96812.1 - 0.14 11.2 0.2 0.76 8.8 0.0 2.1 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI cobW PF02492.14 AIN96812.1 - 0.16 11.4 0.0 0.25 10.7 0.0 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_17 PF13207.1 AIN96812.1 - 0.17 12.7 0.0 0.42 11.4 0.0 1.8 1 0 0 1 1 1 0 AAA domain DUF87 PF01935.12 AIN96812.1 - 0.29 10.9 0.2 0.51 10.1 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function DUF87 ABC2_membrane_3 PF12698.2 AIN96812.1 - 0.38 9.7 19.3 0.027 13.4 9.8 1.7 2 0 0 2 2 2 0 ABC-2 family transporter protein AAA_24 PF13479.1 AIN96812.1 - 0.55 9.7 1.3 1 8.8 0.9 1.3 1 0 0 1 1 1 0 AAA domain RecO_C PF02565.10 AIN96812.1 - 1.9 8.3 4.4 0.69 9.7 0.5 2.1 2 1 0 2 2 2 0 Recombination protein O C terminal HEAT_2 PF13646.1 AIN96815.1 - 2.9e-21 75.5 14.3 1e-08 35.3 0.1 7.0 4 1 4 8 8 8 7 HEAT repeats HEAT PF02985.17 AIN96815.1 - 2e-19 67.8 28.5 0.0022 17.9 0.0 11.0 11 0 0 11 11 11 7 HEAT repeat Adaptin_N PF01602.15 AIN96815.1 - 3.8e-05 22.2 1.8 2.4 6.3 0.0 3.8 4 1 1 5 5 5 3 Adaptin N terminal region CLASP_N PF12348.3 AIN96815.1 - 0.0041 16.5 3.3 0.44 9.8 0.1 3.6 3 2 1 4 4 4 1 CLASP N terminal Nipped-B_C PF12830.2 AIN96815.1 - 0.0088 15.7 0.6 4.1 7.0 0.0 2.9 3 0 0 3 3 3 2 Sister chromatid cohesion C-terminus Vac14_Fab1_bd PF12755.2 AIN96815.1 - 0.083 13.2 1.3 36 4.8 0.0 4.9 3 2 3 6 6 6 0 Vacuolar 14 Fab1-binding region Cnd1 PF12717.2 AIN96815.1 - 0.089 12.6 0.1 2.2 8.1 0.0 3.0 3 0 0 3 3 3 0 non-SMC mitotic condensation complex subunit 1 EF-hand_8 PF13833.1 AIN96816.1 - 6.5e-08 32.0 0.0 0.035 13.7 0.0 3.2 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_7 PF13499.1 AIN96816.1 - 1.4e-07 31.5 0.0 3.7e-05 23.7 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_9 PF14658.1 AIN96816.1 - 7.1e-07 29.0 0.0 0.067 13.1 0.0 3.2 2 1 1 3 3 3 2 EF-hand domain EF-hand_6 PF13405.1 AIN96816.1 - 0.00029 20.4 0.1 0.75 9.8 0.0 3.6 4 0 0 4 4 4 2 EF-hand domain DUF2087 PF09860.4 AIN96816.1 - 0.0042 16.8 0.0 0.81 9.4 0.0 2.3 2 0 0 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2087) EF-hand_1 PF00036.27 AIN96816.1 - 0.0053 15.9 0.0 3.2 7.2 0.0 3.5 4 0 0 4 4 4 1 EF hand DUF2267 PF10025.4 AIN96816.1 - 0.0067 16.4 0.3 3.7 7.6 0.1 2.4 2 1 0 2 2 2 2 Uncharacterized conserved protein (DUF2267) UBN2 PF14223.1 AIN96816.1 - 0.044 13.5 0.0 8 6.2 0.0 2.9 2 1 1 3 3 3 0 gag-polypeptide of LTR copia-type MAP65_ASE1 PF03999.7 AIN96817.1 - 2.5e-07 29.7 3.8 2.5e-07 29.7 2.6 2.8 3 0 0 3 3 3 1 Microtubule associated protein (MAP65/ASE1 family) Ribosomal_S3_C PF00189.15 AIN96818.1 - 9.8e-16 57.7 1.0 9.8e-16 57.7 0.7 1.7 2 1 1 3 3 3 1 Ribosomal protein S3, C-terminal domain KH_2 PF07650.12 AIN96818.1 - 1.4e-08 34.1 0.3 3.3e-08 32.9 0.2 1.6 2 0 0 2 2 2 1 KH domain Evr1_Alr PF04777.8 AIN96819.1 - 6.9e-25 86.7 1.4 1.3e-24 85.9 1.0 1.4 1 0 0 1 1 1 1 Erv1 / Alr family ThiF PF00899.16 AIN96820.1 - 6.6e-34 116.6 0.0 1.1e-33 115.8 0.0 1.4 1 0 0 1 1 1 1 ThiF family MoeZ_MoeB PF05237.8 AIN96820.1 - 1.4e-06 27.7 0.3 5e-06 26.0 0.1 2.0 2 0 0 2 2 2 1 MoeZ/MoeB domain 2-Hacid_dh_C PF02826.14 AIN96820.1 - 0.0039 16.3 0.0 0.0079 15.3 0.0 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Shikimate_DH PF01488.15 AIN96820.1 - 0.0072 16.4 0.0 0.014 15.5 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase ApbA PF02558.11 AIN96820.1 - 0.0088 15.4 0.1 0.025 14.0 0.1 1.8 1 1 0 1 1 1 1 Ketopantoate reductase PanE/ApbA UDPG_MGDP_dh_N PF03721.9 AIN96820.1 - 0.036 13.4 0.0 0.06 12.7 0.0 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NAD_Gly3P_dh_N PF01210.18 AIN96820.1 - 0.051 13.3 0.0 0.08 12.6 0.0 1.3 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Rad9 PF04139.8 AIN96821.1 - 5.2e-08 32.3 0.0 4e-05 22.8 0.0 2.9 2 2 0 2 2 2 2 Rad9 Fer4_17 PF13534.1 AIN96822.1 - 3.4e-09 36.8 5.8 4.7e-07 30.0 0.1 1.6 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_8 PF13183.1 AIN96822.1 - 2e-07 30.9 0.6 3.8e-07 30.0 0.4 1.5 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_9 PF13187.1 AIN96822.1 - 3.5e-06 27.1 0.4 0.0025 18.0 0.1 2.2 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_18 PF13746.1 AIN96822.1 - 8.4e-06 26.1 4.2 0.0018 18.6 0.1 2.2 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_10 PF13237.1 AIN96822.1 - 8.9e-05 22.2 0.2 0.00019 21.1 0.1 1.5 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_4 PF12800.2 AIN96822.1 - 0.014 15.6 5.1 0.075 13.4 0.7 2.3 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_7 PF12838.2 AIN96822.1 - 0.035 14.4 3.7 0.14 12.5 2.6 1.9 1 1 0 1 1 1 0 4Fe-4S dicluster domain Fer4_2 PF12797.2 AIN96822.1 - 4.1 7.5 6.9 1.1 9.3 0.8 2.2 2 0 0 2 2 2 0 4Fe-4S binding domain Ribosomal_L6e PF01159.14 AIN96823.1 - 8.5e-32 109.6 0.9 5.4e-31 107.0 0.6 2.0 1 1 0 1 1 1 1 Ribosomal protein L6e KOW PF00467.24 AIN96823.1 - 0.00051 19.6 0.0 0.0019 17.8 0.0 2.0 1 1 1 2 2 2 1 KOW motif OAD_gamma PF04277.8 AIN96823.1 - 3.7 7.9 11.0 0.64 10.4 4.0 2.1 2 0 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain ELFV_dehydrog PF00208.16 AIN96824.1 - 1.4e-43 149.1 0.0 2.6e-43 148.3 0.0 1.4 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Bac_GDH PF05088.7 AIN96824.1 - 4.4e-19 67.5 0.0 4.1e-10 37.8 0.0 2.4 2 0 0 2 2 2 2 Bacterial NAD-glutamate dehydrogenase polyprenyl_synt PF00348.12 AIN96825.1 - 1.2e-51 175.1 0.1 1.8e-51 174.4 0.0 1.2 1 0 0 1 1 1 1 Polyprenyl synthetase SQS_PSY PF00494.14 AIN96825.1 - 0.0009 18.6 0.2 0.0027 17.0 0.1 1.9 1 1 0 1 1 1 1 Squalene/phytoene synthase SKIP_SNW PF02731.10 AIN96826.1 - 1.5e-08 34.2 2.7 1.5e-08 34.2 1.9 2.5 1 1 1 2 2 2 1 SKIP/SNW domain V_ATPase_I PF01496.14 AIN96826.1 - 6.4 4.4 6.3 8.5 4.0 4.3 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family AhpC-TSA PF00578.16 AIN96827.1 - 3.3e-37 126.9 0.0 4.3e-37 126.5 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 AIN96827.1 - 2e-14 53.3 0.0 2.5e-14 53.0 0.0 1.1 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.4 AIN96827.1 - 5.6e-13 48.3 0.1 1.5e-12 46.9 0.0 1.8 2 0 0 2 2 2 1 C-terminal domain of 1-Cys peroxiredoxin AhpC-TSA PF00578.16 AIN96829.1 - 2.8e-39 133.6 0.0 3.6e-39 133.2 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 AIN96829.1 - 4.7e-16 58.6 0.0 5.6e-16 58.4 0.0 1.1 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.4 AIN96829.1 - 9.6e-13 47.5 0.1 2.6e-12 46.1 0.0 1.8 2 0 0 2 2 2 1 C-terminal domain of 1-Cys peroxiredoxin TF_Zn_Ribbon PF08271.7 AIN96830.1 - 4.3e-06 25.9 1.1 8.1e-06 25.0 0.7 1.4 1 0 0 1 1 1 1 TFIIB zinc-binding DUF2387 PF09526.5 AIN96830.1 - 0.049 13.5 0.9 0.12 12.3 0.6 1.5 1 0 0 1 1 1 0 Probable metal-binding protein (DUF2387) DUF29 PF01724.11 AIN96830.1 - 0.071 12.9 0.2 0.15 11.8 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function DUF29 zf-ribbon_3 PF13248.1 AIN96830.1 - 2.9 7.1 5.5 15 4.9 3.9 2.1 1 1 1 2 2 2 0 zinc-ribbon domain cNMP_binding PF00027.24 AIN96832.1 - 1.1e-07 31.5 0.0 3.8e-07 29.8 0.0 2.0 1 1 0 1 1 1 1 Cyclic nucleotide-binding domain Pkinase PF00069.20 AIN96833.1 - 4.6e-55 186.5 0.0 7.1e-55 185.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AIN96833.1 - 6.6e-40 136.8 0.0 1.1e-39 136.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase cNMP_binding PF00027.24 AIN96833.1 - 9.6e-29 99.0 0.2 1.1e-14 54.0 0.1 2.7 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain PAS_9 PF13426.1 AIN96833.1 - 9e-10 38.8 0.0 6.8e-08 32.8 0.0 2.9 2 0 0 2 2 2 1 PAS domain PAS PF00989.19 AIN96833.1 - 3.3e-07 30.0 0.0 1.2e-06 28.3 0.0 2.0 1 0 0 1 1 1 1 PAS fold Kinase-like PF14531.1 AIN96833.1 - 1e-06 27.9 0.0 6.7e-06 25.2 0.0 2.1 2 0 0 2 2 2 1 Kinase-like RIO1 PF01163.17 AIN96833.1 - 0.16 11.3 0.0 0.37 10.1 0.0 1.5 1 0 0 1 1 1 0 RIO1 family Ribosomal_60s PF00428.14 AIN96834.1 - 2e-22 79.3 14.6 2.6e-22 78.9 10.1 1.2 1 0 0 1 1 1 1 60s Acidic ribosomal protein DUF4366 PF14283.1 AIN96834.1 - 0.055 12.8 0.0 0.07 12.5 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) DUF3138 PF11336.3 AIN96834.1 - 2.5 6.1 6.8 2.3 6.3 4.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) Ribosomal_60s PF00428.14 AIN96835.1 - 2e-22 79.3 14.6 2.6e-22 78.9 10.1 1.2 1 0 0 1 1 1 1 60s Acidic ribosomal protein DUF4366 PF14283.1 AIN96835.1 - 0.055 12.8 0.0 0.07 12.5 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) DUF3138 PF11336.3 AIN96835.1 - 2.5 6.1 6.8 2.3 6.3 4.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) Exo_endo_phos PF03372.18 AIN96836.1 - 2.8e-19 70.0 0.1 7.1e-19 68.7 0.0 1.7 2 0 0 2 2 2 1 Endonuclease/Exonuclease/phosphatase family RhoGAP PF00620.22 AIN96836.1 - 2.9e-12 46.4 0.0 5.5e-12 45.5 0.0 1.4 1 0 0 1 1 1 1 RhoGAP domain DnaJ PF00226.26 AIN96837.1 - 6.6e-25 86.6 1.3 1e-24 86.0 0.9 1.3 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.14 AIN96837.1 - 5e-09 36.0 13.4 1e-08 35.0 9.3 1.5 1 0 0 1 1 1 1 DnaJ central domain CTDII PF01556.13 AIN96837.1 - 5.1e-07 29.5 0.0 0.0035 17.2 0.0 3.6 3 1 0 3 3 3 2 DnaJ C terminal domain DUF3450 PF11932.3 AIN96837.1 - 0.21 10.8 0.1 0.32 10.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) Nucleoside_tran PF01733.13 AIN96838.1 - 7.6e-33 113.9 1.3 1.4e-32 113.0 0.9 1.4 1 0 0 1 1 1 1 Nucleoside transporter UFC1 PF08694.6 AIN96839.1 - 4.2e-81 270.1 0.0 4.7e-81 269.9 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-fold modifier-conjugating enzyme 1 UQ_con PF00179.21 AIN96839.1 - 0.00054 19.3 0.2 0.00073 18.9 0.2 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 AIN96839.1 - 0.021 14.7 0.0 0.026 14.4 0.0 1.3 1 0 0 1 1 1 0 RWD domain Prok-E2_B PF14461.1 AIN96839.1 - 0.039 13.6 0.0 0.053 13.2 0.0 1.3 1 0 0 1 1 1 0 Prokaryotic E2 family B DUF2510 PF10708.4 AIN96839.1 - 1.7 8.1 4.4 18 4.8 1.7 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2510) SET PF00856.23 AIN96840.1 - 1.7e-07 31.6 0.1 4.6e-07 30.2 0.0 1.7 2 0 0 2 2 2 1 SET domain Di19_C PF14571.1 AIN96841.1 - 0.0036 17.5 0.7 0.009 16.3 0.5 1.6 1 0 0 1 1 1 1 Stress-induced protein Di19, C-terminal Chorion_3 PF05387.6 AIN96841.1 - 0.28 10.5 3.2 0.46 9.8 2.2 1.2 1 0 0 1 1 1 0 Chorion family 3 IQ PF00612.22 AIN96842.1 - 1.8 8.4 32.0 0.45 10.3 0.7 5.8 5 0 0 5 5 5 0 IQ calmodulin-binding motif DNA_topoisoIV PF00521.15 AIN96843.1 - 3.3e-105 352.3 0.0 5.7e-105 351.6 0.0 1.4 1 0 0 1 1 1 1 DNA gyrase/topoisomerase IV, subunit A Toprim PF01751.17 AIN96843.1 - 2e-11 43.7 0.0 5.3e-11 42.3 0.0 1.7 1 0 0 1 1 1 1 Toprim domain DNA_gyraseB PF00204.20 AIN96843.1 - 1.1e-10 41.0 0.0 2.6e-10 39.7 0.0 1.6 1 0 0 1 1 1 1 DNA gyrase B HATPase_c PF02518.21 AIN96843.1 - 4.8e-07 29.4 0.0 1.2e-06 28.2 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.1 AIN96843.1 - 0.00022 20.8 0.1 0.00057 19.5 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase SAB PF04382.8 AIN96843.1 - 0.0021 17.6 0.2 0.0058 16.2 0.2 1.7 1 0 0 1 1 1 1 SAB domain DUF3045 PF11243.3 AIN96843.1 - 0.039 14.1 0.5 0.11 12.7 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3045) UCH PF00443.24 AIN96844.1 - 2.2e-36 125.3 0.0 3.9e-36 124.5 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase USP7_ICP0_bdg PF12436.3 AIN96844.1 - 9.9e-13 47.8 0.0 1.6e-06 27.5 0.0 3.4 3 1 0 3 3 3 2 ICP0-binding domain of Ubiquitin-specific protease 7 UCH_1 PF13423.1 AIN96844.1 - 1.9e-12 47.2 0.0 4e-12 46.1 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase CorA PF01544.13 AIN96845.1 - 7.8e-25 87.4 7.1 1.3e-22 80.2 1.0 2.3 1 1 0 2 2 2 2 CorA-like Mg2+ transporter protein SHOCT PF09851.4 AIN96845.1 - 1.6e-05 24.1 0.0 2.8e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 Short C-terminal domain Muted PF14942.1 AIN96845.1 - 0.034 14.0 0.5 0.071 12.9 0.4 1.4 1 0 0 1 1 1 0 Organelle biogenesis, Muted-like protein Cyclin_N PF00134.18 AIN96845.1 - 0.042 13.4 0.3 0.09 12.3 0.2 1.5 1 0 0 1 1 1 0 Cyclin, N-terminal domain MIF4G PF02854.14 AIN96846.1 - 3.6e-11 42.8 0.1 6.6e-11 42.0 0.1 1.3 1 0 0 1 1 1 1 MIF4G domain Actin PF00022.14 AIN96847.1 - 5.9e-100 334.4 0.0 6.8e-100 334.2 0.0 1.0 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.8 AIN96847.1 - 0.00049 18.7 0.1 0.075 11.6 0.0 2.3 2 0 0 2 2 2 2 MreB/Mbl protein NIF PF03031.13 AIN96849.1 - 0.055 13.1 0.0 0.17 11.5 0.0 2.0 1 1 0 1 1 1 0 NLI interacting factor-like phosphatase RabGAP-TBC PF00566.13 AIN96851.1 - 3.4e-05 23.4 0.3 7.1e-05 22.3 0.2 1.4 1 0 0 1 1 1 1 Rab-GTPase-TBC domain DUF3294 PF07957.6 AIN96851.1 - 0.062 12.8 2.2 0.11 12.0 1.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3294) 2OG-FeII_Oxy PF03171.15 AIN96852.1 - 5.9e-11 42.5 0.0 1.8e-10 41.0 0.0 1.7 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Actin PF00022.14 AIN96853.1 - 1.8e-70 237.3 0.0 2.6e-70 236.8 0.0 1.2 1 0 0 1 1 1 1 Actin RE_Eco29kI PF09517.5 AIN96853.1 - 0.095 12.0 0.0 0.15 11.3 0.0 1.2 1 0 0 1 1 1 0 Eco29kI restriction endonuclease DUF1796 PF08795.5 AIN96854.1 - 1.9e-47 161.0 0.0 3.2e-47 160.2 0.0 1.4 1 0 0 1 1 1 1 Putative papain-like cysteine peptidase (DUF1796) Nop PF01798.13 AIN96855.1 - 1.4e-53 180.1 0.8 1.4e-53 180.1 0.5 1.9 2 0 0 2 2 2 1 Putative snoRNA binding domain NOSIC PF08060.8 AIN96855.1 - 4e-27 93.7 0.0 7.6e-27 92.8 0.0 1.5 1 0 0 1 1 1 1 NOSIC (NUC001) domain NOP5NT PF08156.8 AIN96855.1 - 4.3e-05 23.5 1.0 0.13 12.4 0.1 2.6 1 1 1 2 2 2 2 NOP5NT (NUC127) domain DUF3306 PF11748.3 AIN96855.1 - 0.14 12.7 1.7 0.63 10.7 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3306) TMEM164 PF14808.1 AIN96856.1 - 2.7e-10 39.8 4.3 3.3e-10 39.5 2.6 1.4 1 1 0 1 1 1 1 TMEM164 family BRI3BP PF14965.1 AIN96856.1 - 0.078 12.3 2.0 5.1 6.4 0.1 2.7 2 1 0 2 2 2 0 Negative regulator of p53/TP53 Whib PF02467.11 AIN96857.1 - 0.024 14.9 1.7 0.26 11.6 0.1 2.5 2 0 0 2 2 2 0 Transcription factor WhiB zf-RING_2 PF13639.1 AIN96858.1 - 1.5e-12 47.1 9.1 3.1e-12 46.1 6.3 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 AIN96858.1 - 1.8e-07 31.0 8.7 3.4e-07 30.1 6.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 AIN96858.1 - 5e-07 29.7 6.3 1.5e-06 28.2 4.4 1.8 1 1 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_3 PF13920.1 AIN96858.1 - 1.3e-06 27.9 6.1 2.4e-06 27.1 4.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 AIN96858.1 - 5.5e-05 22.7 6.3 0.0001 21.9 4.4 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 AIN96858.1 - 0.00014 21.4 3.7 0.00028 20.5 2.6 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.20 AIN96858.1 - 0.00016 21.2 7.7 0.00029 20.4 5.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) FANCL_C PF11793.3 AIN96858.1 - 0.014 15.3 8.0 0.28 11.1 5.5 2.4 1 1 0 1 1 1 0 FANCL C-terminal domain zf-Apc11 PF12861.2 AIN96858.1 - 0.031 14.0 5.1 0.091 12.6 3.5 1.8 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Nucleo_P87 PF07267.6 AIN96858.1 - 0.1 11.3 0.2 0.14 10.8 0.1 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 MutS_V PF00488.16 AIN96859.1 - 3.1e-57 193.7 0.0 1.1e-56 191.8 0.0 1.8 1 1 0 1 1 1 1 MutS domain V MutS_III PF05192.13 AIN96859.1 - 3.8e-30 105.2 0.2 6.1e-30 104.5 0.1 1.4 1 0 0 1 1 1 1 MutS domain III MutS_I PF01624.15 AIN96859.1 - 6e-19 68.1 0.0 1e-18 67.3 0.0 1.4 1 0 0 1 1 1 1 MutS domain I MutS_IV PF05190.13 AIN96859.1 - 0.0017 18.4 0.0 0.0033 17.5 0.0 1.4 1 0 0 1 1 1 1 MutS family domain IV tRNA-synt_1c PF00749.16 AIN96861.1 - 3.8e-100 334.6 0.0 4.9e-100 334.2 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.13 AIN96861.1 - 2.2e-39 134.9 0.0 3.6e-39 134.2 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain PCNA_N PF00705.13 AIN96862.1 - 1.2e-41 141.1 2.0 1.7e-41 140.6 0.9 1.6 2 0 0 2 2 2 1 Proliferating cell nuclear antigen, N-terminal domain PCNA_C PF02747.10 AIN96862.1 - 4e-37 126.9 0.2 2.6e-19 69.4 0.1 2.3 1 1 1 2 2 2 2 Proliferating cell nuclear antigen, C-terminal domain Rad9 PF04139.8 AIN96862.1 - 1.9e-08 33.7 0.0 2.3e-08 33.4 0.0 1.2 1 0 0 1 1 1 1 Rad9 Rad1 PF02144.11 AIN96862.1 - 5.7e-05 22.0 0.3 0.0013 17.5 0.2 2.1 1 1 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 Hus1 PF04005.7 AIN96862.1 - 0.0013 17.7 0.1 0.089 11.7 0.0 2.2 2 0 0 2 2 2 2 Hus1-like protein GHMP_kinases_N PF00288.21 AIN96863.1 - 4.1e-12 45.9 2.3 5.1e-12 45.6 0.3 2.1 2 0 0 2 2 2 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 AIN96863.1 - 9.4e-05 22.5 0.5 0.00067 19.8 0.2 2.2 2 0 0 2 2 2 1 GHMP kinases C terminal ICE2 PF08426.5 AIN96864.1 - 0.033 12.8 0.0 0.039 12.5 0.0 1.1 1 0 0 1 1 1 0 ICE2 Grp1_Fun34_YaaH PF01184.14 AIN96864.1 - 0.052 12.8 0.0 0.071 12.3 0.0 1.1 1 0 0 1 1 1 0 GPR1/FUN34/yaaH family Ribosomal_L7Ae PF01248.21 AIN96865.1 - 5.5e-25 86.7 0.1 6.5e-25 86.4 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family PELOTA_1 PF15608.1 AIN96865.1 - 0.00052 19.7 0.0 0.00071 19.3 0.0 1.2 1 0 0 1 1 1 1 PELOTA RNA binding domain RNase_P_pop3 PF08228.6 AIN96865.1 - 0.0018 18.0 0.1 0.0021 17.9 0.1 1.1 1 0 0 1 1 1 1 RNase P subunit Pop3 PDEase_I PF00233.14 AIN96866.1 - 4e-59 200.2 0.1 1.2e-58 198.7 0.0 1.8 2 0 0 2 2 2 1 3'5'-cyclic nucleotide phosphodiesterase GAF PF01590.21 AIN96866.1 - 7.7e-41 139.7 0.0 3.1e-20 72.8 0.0 2.9 3 0 0 3 3 3 2 GAF domain GAF_3 PF13492.1 AIN96866.1 - 2.1e-19 69.9 0.1 9.1e-10 38.7 0.0 3.5 3 0 0 3 3 3 3 GAF domain GAF_2 PF13185.1 AIN96866.1 - 1.9e-17 64.1 0.0 1.7e-06 28.6 0.0 3.5 3 0 0 3 3 3 3 GAF domain COG5 PF10392.4 AIN96869.1 - 0.037 13.9 0.1 0.057 13.3 0.0 1.4 1 0 0 1 1 1 0 Golgi transport complex subunit 5 Presenilin PF01080.12 AIN96871.1 - 1.9e-51 175.1 29.4 1e-37 129.9 10.6 2.0 1 1 1 2 2 2 2 Presenilin Wyosine_form PF08608.7 AIN96872.1 - 5.7e-19 67.9 0.0 1.5e-18 66.6 0.0 1.8 1 0 0 1 1 1 1 Wyosine base formation Radical_SAM PF04055.16 AIN96872.1 - 1.4e-18 67.6 0.0 2.6e-18 66.7 0.0 1.5 1 0 0 1 1 1 1 Radical SAM superfamily Pkinase PF00069.20 AIN96874.1 - 6.8e-60 202.4 0.0 8.5e-60 202.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AIN96874.1 - 3.1e-26 92.0 0.0 7.9e-26 90.6 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase FYVE PF01363.16 AIN96874.1 - 4.5e-13 48.8 5.4 4.5e-13 48.8 3.7 1.7 2 0 0 2 2 2 1 FYVE zinc finger APH PF01636.18 AIN96874.1 - 6.1e-05 22.8 0.1 0.0003 20.6 0.0 1.8 1 1 1 2 2 2 1 Phosphotransferase enzyme family FYVE_2 PF02318.11 AIN96874.1 - 0.00049 19.9 3.3 0.00049 19.9 2.3 1.8 2 0 0 2 2 2 1 FYVE-type zinc finger Kinase-like PF14531.1 AIN96874.1 - 0.0036 16.2 0.0 0.0049 15.8 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Choline_kinase PF01633.15 AIN96874.1 - 0.0095 15.5 0.0 0.013 15.1 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase zf-RING_5 PF14634.1 AIN96874.1 - 0.032 13.9 10.7 0.026 14.2 6.0 2.0 2 0 0 2 2 2 0 zinc-RING finger domain NOB1_Zn_bind PF08772.6 AIN96874.1 - 0.3 10.9 4.7 0.7 9.7 3.2 1.6 1 0 0 1 1 1 0 Nin one binding (NOB1) Zn-ribbon like zf-C3HC4_2 PF13923.1 AIN96874.1 - 0.82 9.7 8.0 0.79 9.8 3.3 2.5 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Cnd1 PF12717.2 AIN96875.1 - 1.2e-37 129.4 3.2 1.6e-33 116.0 0.0 4.3 4 1 0 4 4 4 2 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.17 AIN96875.1 - 1.2e-07 31.2 3.5 0.45 10.7 0.0 6.7 6 0 0 6 6 6 2 HEAT repeat HEAT_2 PF13646.1 AIN96875.1 - 6e-07 29.6 0.4 0.081 13.2 0.0 4.8 2 2 1 3 3 3 3 HEAT repeats HEAT_EZ PF13513.1 AIN96875.1 - 0.00059 20.2 0.1 14 6.3 0.0 4.4 3 0 0 3 3 3 1 HEAT-like repeat Cnd1_N PF12922.2 AIN96875.1 - 0.016 14.8 0.0 0.077 12.6 0.0 2.1 2 0 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1, N-term SR-25 PF10500.4 AIN96876.1 - 0.017 14.6 7.1 0.027 13.9 4.9 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein SDA1 PF05285.7 AIN96876.1 - 0.28 10.4 7.1 0.38 9.9 4.9 1.2 1 0 0 1 1 1 0 SDA1 YL1 PF05764.8 AIN96876.1 - 0.33 10.5 9.4 0.63 9.5 6.5 1.4 1 0 0 1 1 1 0 YL1 nuclear protein ASF1_hist_chap PF04729.8 AIN96877.1 - 8.2e-32 109.9 0.0 9.5e-32 109.7 0.0 1.0 1 0 0 1 1 1 1 ASF1 like histone chaperone Ribosomal_L18e PF00828.14 AIN96878.1 - 0.033 14.5 0.0 0.058 13.7 0.0 1.5 1 1 0 1 1 1 0 Ribosomal protein L18e/L15 ADK PF00406.17 AIN96879.1 - 7e-10 38.9 0.0 0.00019 21.3 0.0 2.2 1 1 1 2 2 2 2 Adenylate kinase AAA_17 PF13207.1 AIN96879.1 - 1.5e-09 38.7 0.1 3.8e-09 37.4 0.1 1.7 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 AIN96879.1 - 9.4e-06 25.5 0.0 0.0001 22.1 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 AIN96879.1 - 1.2e-05 25.6 0.0 3e-05 24.3 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 AIN96879.1 - 2e-05 24.2 0.2 4.2e-05 23.2 0.1 1.5 1 0 0 1 1 1 1 Part of AAA domain AAA_28 PF13521.1 AIN96879.1 - 0.00011 22.1 0.0 0.00021 21.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 AIN96879.1 - 0.00084 18.4 0.2 0.0084 15.2 0.0 2.3 3 0 0 3 3 3 1 Zeta toxin SRP54 PF00448.17 AIN96879.1 - 0.001 18.5 0.1 0.0016 17.9 0.0 1.3 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain AAA_22 PF13401.1 AIN96879.1 - 0.0011 19.0 0.4 0.0061 16.6 0.1 2.1 1 1 1 2 2 2 1 AAA domain AAA_16 PF13191.1 AIN96879.1 - 0.0015 18.5 0.0 0.003 17.5 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain cobW PF02492.14 AIN96879.1 - 0.0016 17.9 0.0 0.0023 17.4 0.0 1.2 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain AAA PF00004.24 AIN96879.1 - 0.0018 18.4 0.0 0.0029 17.8 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 AIN96879.1 - 0.0037 16.9 0.1 0.014 15.1 0.0 1.9 1 1 1 2 2 2 1 AAA domain (dynein-related subfamily) NACHT PF05729.7 AIN96879.1 - 0.0046 16.6 0.1 0.0082 15.8 0.1 1.4 1 0 0 1 1 1 1 NACHT domain AAA_10 PF12846.2 AIN96879.1 - 0.0074 15.7 0.0 0.013 15.0 0.0 1.4 1 0 0 1 1 1 1 AAA-like domain AAA_25 PF13481.1 AIN96879.1 - 0.0098 15.3 0.0 0.016 14.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain NTPase_1 PF03266.10 AIN96879.1 - 0.011 15.4 0.1 0.019 14.6 0.0 1.3 1 0 0 1 1 1 0 NTPase UPF0079 PF02367.12 AIN96879.1 - 0.012 15.1 0.0 0.023 14.3 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 RuvB_N PF05496.7 AIN96879.1 - 0.014 14.4 0.0 0.024 13.6 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus AAA_14 PF13173.1 AIN96879.1 - 0.014 15.2 0.0 0.029 14.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain MobB PF03205.9 AIN96879.1 - 0.017 14.7 0.1 0.033 13.9 0.1 1.4 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_29 PF13555.1 AIN96879.1 - 0.018 14.5 0.0 0.032 13.7 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain T2SE PF00437.15 AIN96879.1 - 0.022 13.6 0.0 0.036 12.9 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein SRPRB PF09439.5 AIN96879.1 - 0.033 13.4 0.0 0.057 12.6 0.0 1.4 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit IstB_IS21 PF01695.12 AIN96879.1 - 0.037 13.4 0.2 0.085 12.2 0.0 1.6 2 0 0 2 2 2 0 IstB-like ATP binding protein APS_kinase PF01583.15 AIN96879.1 - 0.041 13.5 0.0 0.064 12.9 0.0 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase PhoH PF02562.11 AIN96879.1 - 0.048 12.8 0.1 0.085 12.0 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein Sigma54_activ_2 PF14532.1 AIN96879.1 - 0.064 13.3 0.0 0.12 12.3 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain KTI12 PF08433.5 AIN96879.1 - 0.065 12.4 0.0 0.1 11.7 0.0 1.3 1 0 0 1 1 1 0 Chromatin associated protein KTI12 AAA_24 PF13479.1 AIN96879.1 - 0.068 12.7 0.0 0.094 12.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain Cytidylate_kin2 PF13189.1 AIN96879.1 - 0.077 12.8 0.0 0.13 12.1 0.0 1.4 1 0 0 1 1 1 0 Cytidylate kinase-like family Sigma54_activat PF00158.21 AIN96879.1 - 0.08 12.4 0.0 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain Mg_chelatase PF01078.16 AIN96879.1 - 0.089 11.9 0.0 0.15 11.2 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Thymidylate_kin PF02223.12 AIN96879.1 - 0.092 12.1 0.0 5.6 6.2 0.0 2.2 2 0 0 2 2 2 0 Thymidylate kinase DAP3 PF10236.4 AIN96879.1 - 0.1 11.5 0.0 0.18 10.6 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 ResIII PF04851.10 AIN96879.1 - 0.1 12.4 0.0 0.15 11.8 0.0 1.4 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit CoaE PF01121.15 AIN96879.1 - 0.11 11.9 1.2 0.15 11.4 0.1 1.7 2 0 0 2 2 2 0 Dephospho-CoA kinase PduV-EutP PF10662.4 AIN96879.1 - 0.12 11.9 0.0 0.23 10.9 0.0 1.5 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation ABC_tran PF00005.22 AIN96879.1 - 0.13 12.5 0.0 0.25 11.6 0.0 1.4 1 0 0 1 1 1 0 ABC transporter PrmA PF06325.8 AIN96880.1 - 1.8e-05 24.0 0.3 2.6e-05 23.4 0.2 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_26 PF13659.1 AIN96880.1 - 2.5e-05 24.2 0.2 5.6e-05 23.1 0.1 1.6 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 AIN96880.1 - 0.0011 18.3 0.0 0.0018 17.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_18 PF12847.2 AIN96880.1 - 0.002 18.6 0.0 0.0037 17.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.6 AIN96880.1 - 0.02 13.5 0.0 0.03 13.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) Cons_hypoth95 PF03602.10 AIN96880.1 - 0.069 12.5 0.0 0.11 11.9 0.0 1.2 1 0 0 1 1 1 0 Conserved hypothetical protein 95 CMAS PF02353.15 AIN96880.1 - 0.076 12.0 0.1 0.15 11.1 0.1 1.5 1 1 0 1 1 1 0 Mycolic acid cyclopropane synthetase PCMT PF01135.14 AIN96880.1 - 0.099 12.1 0.1 0.14 11.6 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_24 PF13578.1 AIN96880.1 - 0.1 13.4 0.3 0.61 10.9 0.0 2.2 2 0 0 2 2 2 0 Methyltransferase domain 2OG-FeII_Oxy_3 PF13640.1 AIN96881.1 - 4.4e-13 49.5 0.0 8.8e-13 48.6 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.1 AIN96881.1 - 1.1e-06 28.1 0.1 3e-06 26.7 0.1 1.7 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily PhyH PF05721.8 AIN96881.1 - 0.00014 21.9 0.0 0.00027 21.0 0.0 1.4 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Pox_C4_C10 PF03336.8 AIN96881.1 - 0.01 14.6 0.0 0.035 12.8 0.0 1.9 2 1 0 2 2 2 0 Poxvirus C4/C10 protein TPR_6 PF13174.1 AIN96881.1 - 0.02 15.3 0.2 0.079 13.4 0.1 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat DEAD PF00270.24 AIN96882.1 - 1.1e-17 64.0 0.0 1.9e-15 56.7 0.0 2.3 1 1 1 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.26 AIN96882.1 - 2.2e-14 53.0 0.0 5.4e-14 51.8 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 AIN96882.1 - 0.045 13.5 0.0 0.1 12.4 0.0 1.8 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit SecA_DEAD PF07517.9 AIN96882.1 - 0.14 11.4 0.0 0.3 10.3 0.0 1.4 1 0 0 1 1 1 0 SecA DEAD-like domain AAA PF00004.24 AIN96883.1 - 3.8e-45 153.3 0.0 1.6e-44 151.3 0.0 2.1 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 AIN96883.1 - 3.9e-07 29.3 0.0 7.9e-07 28.3 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_2 PF07724.9 AIN96883.1 - 0.00011 22.1 0.0 0.00032 20.6 0.0 1.8 2 0 0 2 2 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.1 AIN96883.1 - 0.00029 20.8 0.1 0.011 15.7 0.0 3.2 2 2 1 3 3 3 1 AAA ATPase domain Vps4_C PF09336.5 AIN96883.1 - 0.00057 19.7 0.0 0.0013 18.6 0.0 1.6 1 0 0 1 1 1 1 Vps4 C terminal oligomerisation domain AAA_5 PF07728.9 AIN96883.1 - 0.00076 19.2 0.0 0.0029 17.3 0.0 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.12 AIN96883.1 - 0.001 18.5 0.0 0.0027 17.1 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_14 PF13173.1 AIN96883.1 - 0.0011 18.8 0.0 0.0021 17.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 AIN96883.1 - 0.0016 19.2 0.0 0.0059 17.4 0.0 2.0 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 AIN96883.1 - 0.0016 18.5 0.1 0.015 15.4 0.0 2.5 2 1 1 3 3 2 1 AAA domain AAA_33 PF13671.1 AIN96883.1 - 0.0024 17.7 0.0 0.0056 16.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.17 AIN96883.1 - 0.0045 17.1 0.0 0.0091 16.1 0.0 1.5 1 0 0 1 1 1 1 RNA helicase Parvo_NS1 PF01057.12 AIN96883.1 - 0.0081 15.0 0.0 0.013 14.3 0.0 1.2 1 0 0 1 1 1 1 Parvovirus non-structural protein NS1 TIP49 PF06068.8 AIN96883.1 - 0.013 14.2 0.0 0.023 13.4 0.0 1.3 1 0 0 1 1 1 0 TIP49 C-terminus Zeta_toxin PF06414.7 AIN96883.1 - 0.013 14.5 0.0 0.034 13.2 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin Mg_chelatase PF01078.16 AIN96883.1 - 0.018 14.2 0.1 0.036 13.2 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_28 PF13521.1 AIN96883.1 - 0.024 14.6 0.0 0.07 13.0 0.0 1.8 1 0 0 1 1 1 0 AAA domain PhoH PF02562.11 AIN96883.1 - 0.032 13.4 0.0 0.068 12.3 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein KaiC PF06745.8 AIN96883.1 - 0.047 12.7 0.0 0.092 11.8 0.0 1.4 1 0 0 1 1 1 0 KaiC ABC_tran PF00005.22 AIN96883.1 - 0.065 13.5 0.0 0.13 12.5 0.0 1.4 1 0 0 1 1 1 0 ABC transporter NB-ARC PF00931.17 AIN96883.1 - 0.13 11.1 0.0 0.22 10.3 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain AAA_24 PF13479.1 AIN96883.1 - 0.14 11.6 0.2 0.23 11.0 0.1 1.2 1 0 0 1 1 1 0 AAA domain SKI PF01202.17 AIN96883.1 - 0.18 11.6 0.0 0.46 10.3 0.0 1.7 1 0 0 1 1 1 0 Shikimate kinase AAA_18 PF13238.1 AIN96883.1 - 0.24 11.6 0.0 0.46 10.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain Kelch_4 PF13418.1 AIN96885.1 - 2.1e-36 123.4 0.4 1.3e-10 40.8 0.0 6.8 5 1 1 6 6 6 6 Galactose oxidase, central domain Kelch_3 PF13415.1 AIN96885.1 - 4.2e-33 112.7 1.0 5.2e-10 39.2 0.0 7.0 7 0 0 7 7 7 5 Galactose oxidase, central domain Kelch_5 PF13854.1 AIN96885.1 - 1.4e-25 88.7 2.0 0.0035 17.2 0.0 6.6 6 0 0 6 6 6 6 Kelch motif DUF4110 PF13422.1 AIN96885.1 - 8.6e-21 73.5 10.5 8.6e-21 73.5 7.3 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4110) Kelch_6 PF13964.1 AIN96885.1 - 8.9e-19 66.8 6.8 8.9e-05 22.4 0.0 6.5 4 2 2 6 6 6 6 Kelch motif Kelch_1 PF01344.20 AIN96885.1 - 1.2e-18 66.3 0.6 0.0016 17.9 0.0 5.8 6 0 0 6 6 6 5 Kelch motif Kelch_2 PF07646.10 AIN96885.1 - 1.7e-10 40.2 6.8 0.07 12.9 0.1 6.3 6 0 0 6 6 6 2 Kelch motif Cytochrom_NNT PF03264.9 AIN96885.1 - 0.16 11.3 0.7 0.4 10.0 0.5 1.6 1 0 0 1 1 1 0 NapC/NirT cytochrome c family, N-terminal region MORN PF02493.15 AIN96887.1 - 2.5e-13 48.9 9.0 1.3e-07 30.9 0.6 4.8 4 0 0 4 4 4 3 MORN repeat DUF4149 PF13664.1 AIN96887.1 - 0.28 11.2 0.1 0.28 11.2 0.1 3.6 3 1 0 3 3 3 0 Domain of unknown function (DUF4149) APH PF01636.18 AIN96888.1 - 1.4e-12 47.8 0.0 3.1e-12 46.7 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family HAD_2 PF13419.1 AIN96888.1 - 0.037 14.2 0.1 1.5 9.0 0.0 3.2 2 1 2 4 4 4 0 Haloacid dehalogenase-like hydrolase eIF-1a PF01176.14 AIN96890.1 - 1e-18 66.4 0.4 1.5e-18 65.9 0.3 1.2 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 YL1 PF05764.8 AIN96890.1 - 0.17 11.5 3.4 0.28 10.7 2.3 1.3 1 0 0 1 1 1 0 YL1 nuclear protein Ribosomal_L17 PF01196.14 AIN96892.1 - 4.6e-14 52.7 0.0 6.7e-14 52.2 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L17 DUF3794 PF12673.2 AIN96893.1 - 0.44 10.7 0.0 1.1 9.5 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3794) DUF2262 PF10020.4 AIN96893.1 - 0.57 10.3 0.1 52 4.0 0.0 2.5 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2262) CD52 PF15116.1 AIN96894.1 - 0.076 12.8 0.4 0.21 11.4 0.3 1.7 1 0 0 1 1 1 0 CAMPATH-1 antigen Las1 PF04031.8 AIN96895.1 - 1.4e-40 138.4 0.0 2.5e-40 137.6 0.0 1.4 1 0 0 1 1 1 1 Las1-like DUF3176 PF11374.3 AIN96895.1 - 0.031 14.1 1.5 0.52 10.2 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3176) Mito_carr PF00153.22 AIN96896.1 - 1.9e-65 216.5 0.5 2e-22 78.7 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Mito_carr PF00153.22 AIN96897.1 - 7.3e-55 182.6 6.6 7.2e-19 67.2 0.1 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein DSPc PF00782.15 AIN96899.1 - 3e-08 33.3 0.0 4.1e-08 32.8 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 AIN96899.1 - 1.4e-05 24.5 0.0 2.1e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Radical_SAM PF04055.16 AIN96900.1 - 9e-14 51.9 0.2 3.6e-13 50.0 0.0 2.1 2 1 1 3 3 3 1 Radical SAM superfamily Acetyltransf_1 PF00583.19 AIN96900.1 - 2.1e-10 40.4 0.2 4.1e-09 36.3 0.1 2.5 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 AIN96900.1 - 0.0089 16.1 0.8 0.053 13.6 0.1 2.6 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 AIN96900.1 - 0.1 12.7 0.0 0.24 11.5 0.0 1.7 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain DSPc PF00782.15 AIN96901.1 - 9.8e-09 34.9 0.0 1.2e-08 34.6 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 AIN96901.1 - 1.3e-06 27.9 0.0 3.7e-06 26.4 0.0 1.4 1 1 1 2 2 2 1 Protein-tyrosine phosphatase Abhydrolase_5 PF12695.2 AIN96902.1 - 4.1e-25 88.2 0.0 6.3e-25 87.6 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 AIN96902.1 - 5.7e-18 65.6 0.0 8.7e-18 65.0 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Ank_4 PF13637.1 AIN96902.1 - 4.5e-09 36.5 0.6 6.5e-06 26.5 0.1 3.9 3 1 1 4 4 3 2 Ankyrin repeats (many copies) Ank_5 PF13857.1 AIN96902.1 - 4.2e-08 33.1 0.1 3.3e-06 27.1 0.0 2.9 3 0 0 3 3 2 1 Ankyrin repeats (many copies) Ank_2 PF12796.2 AIN96902.1 - 5.8e-08 32.9 0.1 3e-06 27.4 0.0 2.5 2 1 0 2 2 2 1 Ankyrin repeats (3 copies) Peptidase_S9 PF00326.16 AIN96902.1 - 3.7e-06 26.3 0.2 0.00046 19.4 0.1 2.3 1 1 0 1 1 1 1 Prolyl oligopeptidase family Ank_3 PF13606.1 AIN96902.1 - 5.7e-06 26.0 0.1 0.00011 22.0 0.0 2.8 2 0 0 2 2 2 1 Ankyrin repeat Ank PF00023.25 AIN96902.1 - 2.5e-05 23.8 0.0 0.00013 21.5 0.0 2.3 3 0 0 3 3 3 1 Ankyrin repeat AXE1 PF05448.7 AIN96902.1 - 8.8e-05 21.1 0.6 0.01 14.3 0.4 2.3 1 1 0 1 1 1 1 Acetyl xylan esterase (AXE1) Hydrolase_4 PF12146.3 AIN96902.1 - 0.0013 18.5 0.8 0.0055 16.5 0.1 2.1 2 0 0 2 2 2 1 Putative lysophospholipase Abhydrolase_1 PF00561.15 AIN96902.1 - 0.002 17.7 0.1 0.81 9.1 0.1 2.5 1 1 1 2 2 2 2 alpha/beta hydrolase fold Peptidase_S15 PF02129.13 AIN96902.1 - 0.011 15.2 0.0 0.24 10.7 0.0 2.2 2 0 0 2 2 2 0 X-Pro dipeptidyl-peptidase (S15 family) DUF2424 PF10340.4 AIN96902.1 - 0.11 11.1 0.0 4.2 5.9 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2424) PPR_3 PF13812.1 AIN96903.1 - 0.042 14.1 1.8 49 4.5 0.2 5.0 4 0 0 4 4 4 0 Pentatricopeptide repeat domain GRASP55_65 PF04495.9 AIN96904.1 - 0.0007 19.5 0.0 0.0011 18.9 0.0 1.4 1 0 0 1 1 1 1 GRASP55/65 PDZ-like domain PDZ_2 PF13180.1 AIN96904.1 - 0.11 12.3 0.0 0.3 11.0 0.0 1.7 1 0 0 1 1 1 0 PDZ domain Herpes_UL25 PF01499.11 AIN96904.1 - 9.5 4.3 11.1 1.5e+02 0.4 7.7 2.0 1 1 0 1 1 1 0 Herpesvirus UL25 family Pkinase PF00069.20 AIN96905.1 - 1.8e-64 217.3 0.0 2.4e-64 217.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AIN96905.1 - 2.2e-46 158.0 0.0 2.8e-46 157.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 AIN96905.1 - 0.0031 16.5 0.0 0.0071 15.3 0.0 1.5 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 AIN96905.1 - 0.044 13.5 0.1 0.32 10.6 0.0 2.2 2 0 0 2 2 2 0 Phosphotransferase enzyme family CT47 PF15623.1 AIN96905.1 - 9.4 5.8 9.2 17 5.0 6.4 1.4 1 0 0 1 1 1 0 Cancer/testis gene family 47 PPR_3 PF13812.1 AIN96906.1 - 0.042 14.1 1.8 49 4.5 0.2 5.0 4 0 0 4 4 4 0 Pentatricopeptide repeat domain Met_10 PF02475.11 AIN96907.1 - 3.8e-48 163.7 0.1 4.8e-35 120.9 0.0 2.2 2 0 0 2 2 2 2 Met-10+ like-protein Methyltransf_26 PF13659.1 AIN96907.1 - 0.00052 20.0 0.1 0.0016 18.4 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 AIN96907.1 - 0.0036 16.4 0.0 0.0062 15.7 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.9 AIN96907.1 - 0.033 13.5 0.0 0.07 12.5 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase small domain TRM PF02005.11 AIN96907.1 - 0.037 12.9 0.0 0.069 12.0 0.0 1.3 1 0 0 1 1 1 0 N2,N2-dimethylguanosine tRNA methyltransferase FHA PF00498.21 AIN96908.1 - 2.3e-14 53.2 0.0 4.8e-14 52.2 0.0 1.6 1 0 0 1 1 1 1 FHA domain 2OG-FeII_Oxy_2 PF13532.1 AIN96910.1 - 1.6e-57 194.5 0.1 2.2e-57 194.0 0.1 1.2 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily TTL PF03133.10 AIN96913.1 - 5.2e-78 261.9 0.0 2.5e-77 259.6 0.0 2.0 1 1 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.1 AIN96913.1 - 0.0056 15.5 0.0 0.22 10.2 0.0 2.3 2 0 0 2 2 2 1 YheC/D like ATP-grasp ATPgrasp_ST PF14397.1 AIN96913.1 - 0.039 13.0 0.0 3.9 6.4 0.0 2.2 2 0 0 2 2 2 0 Sugar-transfer associated ATP-grasp ATP-grasp_3 PF02655.9 AIN96913.1 - 0.09 12.6 0.0 4.7 7.0 0.0 2.5 2 0 0 2 2 2 0 ATP-grasp domain RimK PF08443.6 AIN96913.1 - 0.16 11.3 0.0 4.7 6.6 0.0 2.2 2 0 0 2 2 2 0 RimK-like ATP-grasp domain XRN_N PF03159.13 AIN96914.1 - 4.4e-18 65.5 1.8 1.1e-13 51.1 0.1 3.4 2 1 1 3 3 3 2 XRN 5'-3' exonuclease N-terminus Pyridoxal_deC PF00282.14 AIN96917.1 - 4.6e-20 71.3 0.7 3.6e-13 48.6 0.0 2.5 3 0 0 3 3 3 2 Pyridoxal-dependent decarboxylase conserved domain Ribosomal_L21e PF01157.13 AIN96920.1 - 2e-35 120.5 2.9 2.8e-35 120.1 2.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L21e Amastin PF07344.6 AIN96921.1 - 0.01 15.4 13.7 0.013 15.1 9.3 1.4 1 1 0 1 1 1 0 Amastin surface glycoprotein Fucokinase PF07959.7 AIN96922.1 - 1.6e-29 102.7 0.0 8.5e-23 80.5 0.0 2.8 2 1 0 2 2 2 2 L-fucokinase GHMP_kinases_N PF00288.21 AIN96922.1 - 5.1e-06 26.4 1.3 5.6e-05 23.1 0.0 2.8 2 0 0 2 2 2 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 AIN96922.1 - 0.00018 21.6 0.0 0.0006 19.9 0.0 1.9 1 0 0 1 1 1 1 GHMP kinases C terminal Amastin PF07344.6 AIN96924.1 - 1e-06 28.4 9.8 1.6e-06 27.7 6.8 1.4 1 1 0 1 1 1 1 Amastin surface glycoprotein DUF2157 PF09925.4 AIN96924.1 - 0.018 14.6 2.8 0.034 13.7 2.0 1.4 1 0 0 1 1 1 0 Predicted membrane protein (DUF2157) Claudin_2 PF13903.1 AIN96924.1 - 0.57 9.8 13.4 0.22 11.2 6.9 1.9 1 1 1 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction DUF4293 PF14126.1 AIN96924.1 - 0.95 9.3 5.1 3.1 7.7 2.1 2.6 1 1 2 3 3 3 0 Domain of unknown function (DUF4293) Ibs_toxin PF13956.1 AIN96924.1 - 0.98 9.2 4.3 2.4 8.0 0.7 2.5 2 0 0 2 2 2 0 Toxin Ibs, type I toxin-antitoxin system Macoilin PF09726.4 AIN96925.1 - 1.2 7.3 11.0 1.6 6.9 7.7 1.1 1 0 0 1 1 1 0 Transmembrane protein MIP-T3 PF10243.4 AIN96925.1 - 2.6 6.4 24.8 4.8 5.5 17.2 1.3 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Rep_3 PF01051.16 AIN96926.1 - 0.05 13.2 0.2 0.077 12.5 0.1 1.2 1 0 0 1 1 1 0 Initiator Replication protein PMEI PF04043.10 AIN96926.1 - 0.69 9.7 6.2 1.4 8.7 0.2 2.3 2 0 0 2 2 2 0 Plant invertase/pectin methylesterase inhibitor DHO_dh PF01180.16 AIN96927.1 - 1.7e-69 234.0 0.0 1.9e-69 233.8 0.0 1.0 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase FMN_dh PF01070.13 AIN96927.1 - 0.0025 16.7 0.5 0.01 14.6 0.1 2.0 2 0 0 2 2 2 1 FMN-dependent dehydrogenase PcrB PF01884.12 AIN96927.1 - 0.026 13.7 0.0 0.039 13.2 0.0 1.2 1 0 0 1 1 1 0 PcrB family OTCace_N PF02729.16 AIN96928.1 - 2.9e-40 137.2 0.2 4.3e-40 136.6 0.2 1.3 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain OTCace PF00185.19 AIN96928.1 - 1.1e-34 119.5 0.2 1.2e-33 116.1 0.1 2.0 2 0 0 2 2 2 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain OMPdecase PF00215.19 AIN96929.1 - 6.4e-39 133.6 0.0 9.3e-39 133.1 0.0 1.2 1 0 0 1 1 1 1 Orotidine 5'-phosphate decarboxylase / HUMPS family Pribosyltran PF00156.22 AIN96929.1 - 4.5e-19 68.3 1.0 1.7e-18 66.5 0.7 2.0 1 1 0 1 1 1 1 Phosphoribosyl transferase domain PRTase_2 PF15609.1 AIN96929.1 - 0.0002 20.7 0.0 0.00038 19.8 0.0 1.4 1 0 0 1 1 1 1 Phosphoribosyl transferase UPRTase PF14681.1 AIN96929.1 - 0.00049 19.3 0.0 0.00097 18.4 0.0 1.5 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase DUF3933 PF13069.1 AIN96929.1 - 0.029 14.0 0.1 11 5.7 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3933) BRX PF08381.6 AIN96929.1 - 0.077 12.0 0.0 0.16 11.0 0.0 1.5 1 0 0 1 1 1 0 Transcription factor regulating root and shoot growth via Pin3 KA1 PF02149.14 AIN96929.1 - 0.084 12.3 0.0 0.65 9.4 0.0 2.3 2 0 0 2 2 2 0 Kinase associated domain 1 Whirly PF08536.6 AIN96929.1 - 0.12 11.8 0.0 0.21 11.0 0.0 1.4 1 0 0 1 1 1 0 Whirly transcription factor Phage_Coat_Gp8 PF05371.7 AIN96929.1 - 1.9 8.1 4.9 0.48 10.0 0.7 2.1 2 0 0 2 2 2 0 Phage major coat protein, Gp8 AAA_17 PF13207.1 AIN96930.1 - 1.5e-06 29.0 0.0 4.8e-06 27.3 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 AIN96930.1 - 0.0014 18.9 0.0 0.0044 17.3 0.0 1.9 2 0 0 2 2 2 1 AAA domain PRK PF00485.13 AIN96930.1 - 0.0084 15.6 0.0 0.068 12.7 0.0 2.1 2 0 0 2 2 2 1 Phosphoribulokinase / Uridine kinase family AAA_33 PF13671.1 AIN96930.1 - 0.017 15.0 0.0 0.042 13.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain MobB PF03205.9 AIN96930.1 - 0.15 11.7 0.0 0.37 10.5 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Amidohydro_4 PF13147.1 AIN96931.1 - 2e-22 80.5 6.1 5.2e-22 79.1 4.2 1.5 1 1 0 1 1 1 1 Amidohydrolase Amidohydro_1 PF01979.15 AIN96931.1 - 2.5e-07 30.7 0.2 3.2e-07 30.3 0.2 1.3 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_5 PF13594.1 AIN96931.1 - 0.00046 19.9 0.1 0.00046 19.9 0.1 2.1 2 0 0 2 2 2 1 Amidohydrolase DHOase PF12890.2 AIN96931.1 - 0.03 14.0 0.1 0.21 11.2 0.1 2.0 1 1 0 1 1 1 0 Dihydro-orotase-like CPSase_L_D2 PF02786.12 AIN96932.1 - 8.6e-101 335.5 0.3 1.3e-76 256.5 0.1 2.3 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_sm_chain PF00988.17 AIN96932.1 - 1.1e-45 154.2 0.0 3e-45 152.9 0.0 1.8 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain GATase PF00117.23 AIN96932.1 - 2.6e-41 141.2 0.0 7.2e-41 139.7 0.0 1.8 1 0 0 1 1 1 1 Glutamine amidotransferase class-I CPSase_L_chain PF00289.17 AIN96932.1 - 1.6e-36 124.7 0.0 3.7e-20 72.0 0.0 2.7 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, N-terminal domain CPSase_L_D3 PF02787.14 AIN96932.1 - 1.1e-32 112.3 0.0 2.2e-32 111.4 0.0 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain ATP-grasp_4 PF13535.1 AIN96932.1 - 1.1e-32 113.2 0.6 5.8e-19 68.5 0.0 2.9 3 0 0 3 3 3 2 ATP-grasp domain ATPgrasp_Ter PF15632.1 AIN96932.1 - 3.9e-21 75.1 0.0 2.3e-15 56.1 0.0 3.4 3 0 0 3 3 3 2 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp PF02222.17 AIN96932.1 - 1.5e-19 69.9 0.2 4.3e-10 39.2 0.0 2.4 2 0 0 2 2 2 2 ATP-grasp domain Arginosuc_synth PF00764.14 AIN96932.1 - 1.1e-13 50.9 0.0 2.9e-13 49.6 0.0 1.6 1 0 0 1 1 1 1 Arginosuccinate synthase MGS PF02142.17 AIN96932.1 - 3.3e-12 46.1 0.0 1.7e-11 43.9 0.0 2.3 2 0 0 2 2 1 1 MGS-like domain Dala_Dala_lig_C PF07478.8 AIN96932.1 - 1.9e-10 40.4 0.3 0.00011 21.7 0.0 2.5 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus Peptidase_C26 PF07722.8 AIN96932.1 - 1.6e-06 27.7 0.2 3.5e-05 23.3 0.1 2.4 1 1 0 1 1 1 1 Peptidase C26 ATP-grasp_3 PF02655.9 AIN96932.1 - 6.8e-05 22.7 0.2 0.0036 17.1 0.0 2.7 2 1 0 2 2 2 1 ATP-grasp domain TrkA_N PF02254.13 AIN96932.1 - 0.018 15.0 0.0 0.095 12.7 0.0 2.2 2 0 0 2 2 1 0 TrkA-N domain DJ-1_PfpI PF01965.19 AIN96932.1 - 0.075 12.4 0.0 0.17 11.3 0.0 1.6 1 0 0 1 1 1 0 DJ-1/PfpI family TP6A_N PF04406.9 AIN96934.1 - 1.6e-09 37.2 0.3 2.9e-09 36.4 0.2 1.4 1 0 0 1 1 1 1 Type IIB DNA topoisomerase DUF2399 PF09664.5 AIN96934.1 - 0.02 14.7 0.4 0.049 13.4 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function C-terminus (DUF2399) RRM_1 PF00076.17 AIN96935.1 - 1.8e-12 46.7 0.0 3.1e-12 45.9 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 AIN96935.1 - 1.6e-07 31.0 0.1 3e-07 30.1 0.1 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 AIN96935.1 - 1.9e-07 30.9 0.0 3.4e-07 30.1 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Pro_isomerase PF00160.16 AIN96935.1 - 3.7e-06 27.2 0.0 0.11 12.7 0.0 2.3 2 0 0 2 2 2 2 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD zf-rbx1 PF12678.2 AIN96936.1 - 2.7e-18 65.8 6.9 3.3e-18 65.5 4.8 1.1 1 0 0 1 1 1 1 RING-H2 zinc finger zf-Apc11 PF12861.2 AIN96936.1 - 9.1e-15 54.2 7.0 1.2e-14 53.8 4.9 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_2 PF13639.1 AIN96936.1 - 1.4e-10 40.8 16.5 7.5e-09 35.2 11.8 2.1 1 1 1 2 2 2 1 Ring finger domain zf-RING_5 PF14634.1 AIN96936.1 - 1.7e-07 30.8 13.0 1.2e-06 28.1 6.2 2.2 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 AIN96936.1 - 7.3e-07 29.1 12.5 4.3e-06 26.6 5.9 2.2 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 AIN96936.1 - 7.8e-07 28.6 13.1 1.8e-05 24.3 5.4 2.3 1 1 1 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.1 AIN96936.1 - 8.7e-06 25.4 5.4 8.7e-06 25.4 3.7 1.9 1 1 1 2 2 2 1 zf-RING of BARD1-type protein zf-C3HC4 PF00097.20 AIN96936.1 - 0.00065 19.3 12.5 0.0034 17.0 8.7 2.1 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 AIN96936.1 - 0.00077 19.1 9.7 0.0029 17.2 6.7 2.0 1 1 0 1 1 1 1 RING-type zinc-finger FANCL_C PF11793.3 AIN96936.1 - 0.0019 18.0 13.1 0.027 14.4 2.6 3.2 1 1 2 3 3 3 1 FANCL C-terminal domain zf-RING_4 PF14570.1 AIN96936.1 - 0.01 15.3 8.6 0.33 10.5 4.1 2.5 2 1 0 2 2 2 0 RING/Ubox like zinc-binding domain Rtf2 PF04641.7 AIN96936.1 - 0.022 13.9 4.4 0.024 13.8 1.2 2.0 1 1 1 2 2 2 0 Rtf2 RING-finger zf-Nse PF11789.3 AIN96936.1 - 0.27 10.7 6.9 1 8.9 4.8 2.0 1 1 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-C3HC4_4 PF15227.1 AIN96936.1 - 0.49 10.2 14.0 19 5.2 1.7 3.2 1 1 2 3 3 3 0 zinc finger of C3HC4-type, RING zf-Di19 PF05605.7 AIN96936.1 - 0.59 10.2 9.8 1.1 9.4 3.1 2.3 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding DUF1272 PF06906.6 AIN96936.1 - 0.71 9.7 10.4 53 3.7 7.2 2.9 1 1 0 1 1 1 0 Protein of unknown function (DUF1272) Prok-RING_1 PF14446.1 AIN96936.1 - 0.99 9.1 12.8 24 4.7 8.7 2.7 1 1 0 1 1 1 0 Prokaryotic RING finger family 1 Prok-RING_4 PF14447.1 AIN96936.1 - 1.4 8.4 13.9 0.23 11.0 4.7 2.2 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 C1_1 PF00130.17 AIN96936.1 - 1.6 8.4 10.5 0.73 9.6 5.5 1.8 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) TerY-C PF15616.1 AIN96936.1 - 3.6 7.5 10.4 3.1e+02 1.2 7.2 2.1 1 1 0 1 1 1 0 TerY-C metal binding domain Reo_sigmaC PF04582.7 AIN96937.1 - 0.29 10.2 24.2 0.036 13.2 1.2 3.6 2 2 2 4 4 4 0 Reovirus sigma C capsid protein LpxK PF02606.9 AIN96938.1 - 0.025 13.5 0.0 0.043 12.7 0.0 1.3 1 0 0 1 1 1 0 Tetraacyldisaccharide-1-P 4'-kinase DUF1738 PF08401.6 AIN96938.1 - 0.045 13.4 0.0 1.4 8.7 0.0 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF1738) Exo_endo_phos PF03372.18 AIN96939.1 - 6.8e-25 88.4 0.1 8.7e-25 88.0 0.0 1.1 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Med3 PF11593.3 AIN96939.1 - 5.8 6.0 5.6 7.2 5.7 3.9 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal eIF2A PF08662.6 AIN96940.1 - 3.9e-39 134.3 0.0 4.4e-31 108.1 0.0 3.2 2 1 1 3 3 3 3 Eukaryotic translation initiation factor eIF2A WD40 PF00400.27 AIN96940.1 - 0.023 14.5 0.2 92 3.1 0.0 4.3 4 0 0 4 4 4 0 WD domain, G-beta repeat LysM PF01476.15 AIN96941.1 - 9e-06 25.4 0.0 0.048 13.5 0.0 2.3 2 0 0 2 2 2 2 LysM domain PACT_coil_coil PF10495.4 AIN96942.1 - 0.049 13.5 0.1 0.14 12.0 0.1 1.8 1 0 0 1 1 1 0 Pericentrin-AKAP-450 domain of centrosomal targeting protein LRR_6 PF13516.1 AIN96943.1 - 4e-13 47.9 7.5 0.25 11.5 0.1 6.9 7 0 0 7 7 7 5 Leucine Rich repeat LRR_1 PF00560.28 AIN96943.1 - 1.9e-07 30.1 3.3 8.2 6.8 0.1 5.9 6 0 0 6 6 6 2 Leucine Rich Repeat LRR_4 PF12799.2 AIN96943.1 - 9.9e-07 28.2 6.0 0.053 13.1 0.0 4.6 4 1 0 4 4 4 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 AIN96943.1 - 0.0041 16.8 10.7 0.0092 15.7 0.1 3.9 4 0 0 4 4 4 1 Leucine rich repeat LRR_7 PF13504.1 AIN96943.1 - 0.0051 16.7 11.5 43 4.9 0.2 6.0 6 0 0 6 6 6 0 Leucine rich repeat UCH PF00443.24 AIN96944.1 - 3.1e-39 134.7 0.0 5.3e-39 133.9 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 AIN96944.1 - 1.5e-20 73.8 0.0 2e-19 70.1 0.0 2.5 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase Transaldolase PF00923.14 AIN96947.1 - 1.4e-96 322.9 0.0 1.6e-96 322.8 0.0 1.0 1 0 0 1 1 1 1 Transaldolase SH3BGR PF04908.10 AIN96948.1 - 0.0072 16.2 0.0 0.016 15.1 0.0 1.5 1 0 0 1 1 1 1 SH3-binding, glutamic acid-rich protein Chorein_N PF12624.2 AIN96949.1 - 1.2e-17 63.5 0.2 2.6e-10 39.8 0.1 2.6 2 0 0 2 2 2 2 N-terminal region of Chorein, a TM vesicle-mediated sorter DUF1162 PF06650.7 AIN96949.1 - 0.00096 18.4 0.0 2.4 7.2 0.0 3.9 4 0 0 4 4 4 1 Protein of unknown function (DUF1162) TFIIS_C PF01096.13 AIN96949.1 - 0.12 12.0 1.7 0.49 10.0 1.2 2.1 1 0 0 1 1 1 0 Transcription factor S-II (TFIIS) Glyco_hydro_18 PF00704.23 AIN96950.1 - 2.4e-50 171.9 0.0 3.7e-50 171.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Mem_trans PF03547.13 AIN96951.1 - 3e-12 45.5 20.7 4.9e-11 41.5 0.0 3.2 3 0 0 3 3 3 3 Membrane transport protein EF-hand_1 PF00036.27 AIN96953.1 - 0.047 13.0 0.0 0.087 12.1 0.0 1.4 1 0 0 1 1 1 0 EF hand Fe-S_biosyn PF01521.15 AIN96954.1 - 1.4e-07 31.4 0.1 1e-06 28.6 0.0 2.3 1 1 0 1 1 1 1 Iron-sulphur cluster biosynthesis JAB PF01398.16 AIN96956.1 - 2.2e-20 72.4 0.0 3.7e-20 71.7 0.0 1.3 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Prok-JAB PF14464.1 AIN96956.1 - 0.00096 18.6 0.0 0.003 17.0 0.0 1.8 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain Pkinase PF00069.20 AIN96958.1 - 2.2e-31 108.9 0.0 8.4e-31 107.0 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AIN96958.1 - 5.1e-24 84.7 0.0 1.7e-23 83.0 0.0 1.8 2 1 0 2 2 2 1 Protein tyrosine kinase EcKinase PF02958.15 AIN96958.1 - 0.021 14.0 0.0 0.035 13.2 0.0 1.3 1 0 0 1 1 1 0 Ecdysteroid kinase zf-H2C2_5 PF13909.1 AIN96958.1 - 0.043 14.0 2.4 0.098 12.9 1.7 1.6 1 0 0 1 1 1 0 C2H2-type zinc-finger domain Nop52 PF05997.7 AIN96959.1 - 2.3e-48 164.4 0.1 1.1e-41 142.6 0.0 3.4 2 1 1 3 3 3 3 Nucleolar protein,Nop52 EF-hand_1 PF00036.27 AIN96962.1 - 2.4e-15 54.5 0.9 9.2e-06 24.6 0.0 4.0 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.1 AIN96962.1 - 9.2e-14 50.0 1.5 0.0021 17.7 0.0 3.9 4 0 0 4 4 4 3 EF-hand domain EF-hand_7 PF13499.1 AIN96962.1 - 2.5e-12 46.7 1.6 1.4e-07 31.5 0.2 3.1 2 2 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.1 AIN96962.1 - 1.9e-09 36.9 0.9 0.0082 15.7 0.0 3.8 3 1 1 4 4 4 3 EF-hand domain pair EF-hand_5 PF13202.1 AIN96962.1 - 2.3e-08 32.9 0.6 0.00099 18.3 0.1 3.6 3 1 0 3 3 3 2 EF hand EF-hand_10 PF14788.1 AIN96962.1 - 0.0031 17.1 0.2 0.89 9.2 0.0 3.2 3 0 0 3 3 3 1 EF hand SPARC_Ca_bdg PF10591.4 AIN96962.1 - 0.004 17.1 0.2 0.016 15.1 0.0 2.0 1 1 1 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region Ribosomal_L11 PF00298.14 AIN96962.1 - 0.061 13.4 0.0 0.15 12.2 0.0 1.6 1 0 0 1 1 1 0 Ribosomal protein L11, RNA binding domain Snf7 PF03357.16 AIN96963.1 - 1e-24 86.8 12.6 1.4e-24 86.4 8.7 1.2 1 0 0 1 1 1 1 Snf7 DUF3801 PF12687.2 AIN96963.1 - 0.00094 18.8 4.2 0.0011 18.6 2.4 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF3801) Dynein_light PF01221.13 AIN96964.1 - 1.3e-26 92.3 0.6 1.5e-26 92.2 0.4 1.1 1 0 0 1 1 1 1 Dynein light chain type 1 Glycos_transf_1 PF00534.15 AIN96965.1 - 1.1e-27 96.4 0.0 1.9e-27 95.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 AIN96965.1 - 1.3e-12 47.9 0.0 3e-12 46.8 0.0 1.6 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.1 AIN96965.1 - 0.0018 18.4 0.0 0.0041 17.3 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 HMG_box_2 PF09011.5 AIN96965.1 - 0.062 13.6 0.0 2.2 8.7 0.0 2.4 2 0 0 2 2 2 0 HMG-box domain Glycogen_syn PF05693.8 AIN96965.1 - 0.13 10.4 0.0 0.2 9.8 0.0 1.2 1 0 0 1 1 1 0 Glycogen synthase Methyltransf_11 PF08241.7 AIN96966.1 - 2.6e-15 56.6 0.0 5.2e-14 52.4 0.0 2.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 AIN96966.1 - 6.4e-12 45.4 0.0 5.8e-11 42.3 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.13 AIN96966.1 - 2.3e-11 43.2 0.0 1.7e-10 40.3 0.0 2.0 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.1 AIN96966.1 - 5.6e-07 29.2 0.0 0.00013 21.5 0.0 2.5 2 1 0 2 2 2 2 Methyltransferase domain Methyltransf_12 PF08242.7 AIN96966.1 - 9.1e-06 26.0 0.0 0.0012 19.2 0.0 2.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 AIN96966.1 - 0.00066 20.0 0.0 0.03 14.6 0.0 2.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 AIN96966.1 - 0.0014 19.1 0.2 0.011 16.3 0.0 2.5 3 0 0 3 3 3 1 Methyltransferase domain Reo_sigmaC PF04582.7 AIN96968.1 - 0.041 13.0 35.1 0.31 10.1 0.3 5.7 2 2 1 5 5 5 0 Reovirus sigma C capsid protein Pkinase PF00069.20 AIN96969.1 - 2e-59 200.8 0.0 2.3e-58 197.3 0.0 2.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AIN96969.1 - 2.6e-29 102.0 0.0 1.3e-19 70.3 0.0 3.1 3 0 0 3 3 3 2 Protein tyrosine kinase Kinase-like PF14531.1 AIN96969.1 - 0.1 11.5 0.0 2.5 6.9 0.0 2.1 2 0 0 2 2 2 0 Kinase-like DUF3184 PF11380.3 AIN96970.1 - 2e-59 201.2 0.2 2.2e-59 201.1 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3184) DUF2113 PF09886.4 AIN96970.1 - 0.099 11.7 0.0 0.14 11.3 0.0 1.4 1 1 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2113) DUF3184 PF11380.3 AIN96972.1 - 3.8e-116 388.7 9.5 4.3e-116 388.5 4.2 2.0 1 1 1 2 2 2 2 Protein of unknown function (DUF3184) DUF3184 PF11380.3 AIN96973.1 - 2.9e-74 250.2 2.4 3.4e-74 250.0 1.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3184) DUF3184 PF11380.3 AIN96974.1 - 4.1e-196 653.0 5.9 5e-196 652.7 4.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3184) GCFC PF07842.7 AIN96974.1 - 0.049 12.9 0.1 0.28 10.5 0.0 2.0 2 0 0 2 2 2 0 GC-rich sequence DNA-binding factor-like protein DUF3184 PF11380.3 AIN96975.1 - 0 1248.4 2.6 0 1248.2 1.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3184) Ufm1 PF03671.9 AIN96976.1 - 2.3e-26 91.3 0.1 2.8e-26 91.0 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin fold modifier 1 protein YwqJ-deaminase PF14431.1 AIN96980.1 - 0.39 10.5 3.4 0.18 11.6 0.4 2.0 2 0 0 2 2 2 0 YwqJ-like deaminase Polyketide_cyc PF03364.15 AIN96981.1 - 8.1e-12 45.2 0.1 7.1e-11 42.2 0.0 2.1 1 1 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Antimicrobial_8 PF08103.6 AIN96981.1 - 0.46 10.5 2.2 6.5 6.8 0.1 3.1 3 0 0 3 3 3 0 Uperin family tRNA_bind PF01588.15 AIN96983.1 - 1.8e-22 78.9 0.0 3.4e-22 78.0 0.0 1.5 1 0 0 1 1 1 1 Putative tRNA binding domain WW PF00397.21 AIN96984.1 - 2.2e-37 126.4 41.6 4.5e-13 48.7 2.6 6.0 6 0 0 6 6 6 5 WW domain Mcp5_PH PF12814.2 AIN96984.1 - 0.087 12.7 0.5 0.62 9.9 0.1 2.5 3 0 0 3 3 3 0 Meiotic cell cortex C-terminal pleckstrin homology Tbf5 PF06331.7 AIN96985.1 - 0.005 16.5 0.0 0.018 14.7 0.0 1.8 1 1 0 1 1 1 1 Transcription factor TFIIH complex subunit Tfb5 Ribosomal_L39 PF00832.15 AIN96988.1 - 2.3e-19 68.5 14.3 2.6e-19 68.3 9.9 1.0 1 0 0 1 1 1 1 Ribosomal L39 protein Methyltransf_FA PF12248.3 AIN96988.1 - 0.081 12.9 0.0 0.089 12.8 0.0 1.1 1 0 0 1 1 1 0 Farnesoic acid 0-methyl transferase Adap_comp_sub PF00928.16 AIN96989.1 - 3.2e-13 49.4 0.0 4.9e-13 48.7 0.0 1.2 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 AIN96989.1 - 0.00065 19.4 0.0 0.0012 18.5 0.0 1.4 1 0 0 1 1 1 1 Clathrin adaptor complex small chain DUF221 PF02714.10 AIN96990.1 - 1.3e-30 106.3 10.0 1.9e-30 105.8 6.9 1.3 1 0 0 1 1 1 1 Domain of unknown function DUF221 Methyltransf_9 PF08003.6 AIN96990.1 - 0.074 11.7 0.1 0.14 10.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) Pro_isomerase PF00160.16 AIN96991.1 - 7.1e-32 110.7 0.0 1.1e-31 110.1 0.0 1.2 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD dsrm PF00035.20 AIN96992.1 - 0.1 13.1 0.1 23 5.6 0.0 3.7 4 0 0 4 4 4 0 Double-stranded RNA binding motif Cullin PF00888.17 AIN96993.1 - 1.2e-31 110.0 0.0 5.3e-17 61.5 0.0 4.5 5 0 0 5 5 5 4 Cullin family Cullin_Nedd8 PF10557.4 AIN96993.1 - 7.8e-19 67.2 0.0 1.4e-18 66.4 0.0 1.4 1 0 0 1 1 1 1 Cullin protein neddylation domain LSM PF01423.17 AIN96996.1 - 0.00012 21.5 0.0 0.00026 20.4 0.0 1.5 1 1 0 1 1 1 1 LSM domain DAGK_acc PF00609.14 AIN97000.1 - 9.8e-22 77.8 0.0 6.9e-21 75.0 0.0 2.2 1 1 1 2 2 2 1 Diacylglycerol kinase accessory domain DAGK_cat PF00781.19 AIN97000.1 - 9.9e-07 28.2 0.0 3.3e-06 26.5 0.0 1.9 1 1 0 1 1 1 1 Diacylglycerol kinase catalytic domain Nrf1_activ_bdg PF10492.4 AIN97001.1 - 0.048 14.1 6.2 7.2 7.1 0.0 4.2 4 0 0 4 4 4 0 Nrf1 activator activation site binding domain Cytochrom_C PF00034.16 AIN97002.1 - 7.9e-10 39.4 0.0 1e-09 39.0 0.0 1.2 1 0 0 1 1 1 1 Cytochrome c Cytochrome_CBB3 PF13442.1 AIN97002.1 - 4e-05 23.6 0.9 0.00033 20.7 0.6 2.0 1 1 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C PF00034.16 AIN97003.1 - 1.5e-09 38.5 0.0 2e-09 38.1 0.0 1.2 1 0 0 1 1 1 1 Cytochrome c Cytochrome_CBB3 PF13442.1 AIN97003.1 - 3.8e-05 23.7 0.9 0.00033 20.7 0.6 2.0 1 1 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III LRR_4 PF12799.2 AIN97004.1 - 7.5e-34 114.8 21.4 0.0026 17.3 0.0 12.1 6 3 5 12 12 12 11 Leucine Rich repeats (2 copies) LRR_6 PF13516.1 AIN97004.1 - 6.7e-15 53.4 25.5 4.8 7.5 0.0 15.9 15 2 2 17 17 17 4 Leucine Rich repeat LRR_8 PF13855.1 AIN97004.1 - 4.3e-12 45.6 37.4 0.00062 19.4 0.1 9.2 7 2 3 10 10 10 6 Leucine rich repeat LRR_9 PF14580.1 AIN97004.1 - 0.0084 15.6 18.6 0.86 9.1 0.3 6.1 4 3 2 6 6 6 2 Leucine-rich repeat LRR_1 PF00560.28 AIN97004.1 - 0.16 12.1 27.8 20 5.7 0.1 11.7 12 2 1 13 13 13 0 Leucine Rich Repeat Crl PF07417.7 AIN97005.1 - 0.67 9.6 0.0 1.5 8.5 0.0 1.5 1 0 0 1 1 1 0 Transcriptional regulator Crl RNA_pol_Rpb1_5 PF04998.12 AIN97006.1 - 1e-60 205.3 0.0 2.8e-60 203.9 0.0 1.7 1 1 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.15 AIN97006.1 - 1e-46 158.9 0.0 1.8e-46 158.1 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.13 AIN97006.1 - 1.3e-29 102.9 0.0 2.9e-29 101.8 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.12 AIN97006.1 - 3e-15 55.8 0.6 8.2e-15 54.4 0.4 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 RNA_pol_Rpb1_1 PF04997.7 AIN97006.1 - 0.058 12.6 0.0 0.16 11.1 0.0 1.7 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 1 Amidase PF01425.16 AIN97007.1 - 7.2e-57 193.1 0.0 3e-56 191.1 0.0 1.8 1 1 0 1 1 1 1 Amidase LSM PF01423.17 AIN97008.1 - 0.00035 20.0 0.0 0.0004 19.8 0.0 1.2 1 0 0 1 1 1 1 LSM domain Arf PF00025.16 AIN97009.1 - 7.6e-49 165.2 0.0 8.6e-49 165.1 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 AIN97009.1 - 3e-11 43.1 0.4 1.8e-09 37.3 0.0 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain SRPRB PF09439.5 AIN97009.1 - 3e-10 39.6 0.0 3.8e-10 39.2 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.17 AIN97009.1 - 2.7e-09 36.6 0.0 3.1e-09 36.4 0.0 1.1 1 0 0 1 1 1 1 Ras family MMR_HSR1 PF01926.18 AIN97009.1 - 1.1e-08 35.0 0.0 1.5e-08 34.5 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase G-alpha PF00503.15 AIN97009.1 - 2e-08 33.3 1.7 6e-05 21.9 0.2 2.6 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.7 AIN97009.1 - 2.1e-07 30.3 0.1 2.6e-07 30.0 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 AIN97009.1 - 2.2e-07 31.3 0.0 3e-07 30.9 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein FeoB_N PF02421.13 AIN97009.1 - 0.00031 20.0 0.1 0.00063 19.0 0.1 1.6 1 1 0 1 1 1 1 Ferrous iron transport protein B AAA_22 PF13401.1 AIN97009.1 - 0.0034 17.5 0.0 0.055 13.6 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 AIN97009.1 - 0.014 15.6 0.0 0.024 14.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain cobW PF02492.14 AIN97009.1 - 0.021 14.2 0.0 2.1 7.7 0.0 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain PduV-EutP PF10662.4 AIN97009.1 - 0.064 12.7 0.0 5.4 6.5 0.0 2.2 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Septin PF00735.13 AIN97009.1 - 0.099 11.6 0.0 0.16 10.9 0.0 1.3 1 0 0 1 1 1 0 Septin OTU PF02338.14 AIN97010.1 - 3.9e-16 59.7 0.0 8.3e-16 58.6 0.0 1.5 1 0 0 1 1 1 1 OTU-like cysteine protease HJURP_mid PF12346.3 AIN97010.1 - 0.013 15.5 0.1 0.71 10.0 0.0 2.5 2 0 0 2 2 2 0 Holliday junction recognition protein-associated repeat EMG1 PF03587.9 AIN97011.1 - 4.5e-75 251.4 0.0 5.6e-75 251.0 0.0 1.1 1 0 0 1 1 1 1 EMG1/NEP1 methyltransferase TRAPP PF04051.11 AIN97012.1 - 2.9e-30 104.8 0.0 3.7e-30 104.4 0.0 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component C_GCAxxG_C_C PF09719.5 AIN97012.1 - 0.12 12.1 0.1 0.63 9.8 0.0 2.1 1 1 0 2 2 2 0 Putative redox-active protein (C_GCAxxG_C_C) ATP-synt_E PF05680.7 AIN97012.1 - 0.15 12.0 0.0 0.58 10.1 0.0 1.9 2 0 0 2 2 2 0 ATP synthase E chain IQ PF00612.22 AIN97013.1 - 0.032 13.8 0.5 0.11 12.2 0.3 1.9 1 0 0 1 1 1 0 IQ calmodulin-binding motif DUF2229 PF09989.4 AIN97013.1 - 0.32 10.4 3.1 0.23 10.9 0.5 1.9 1 1 0 1 1 1 0 CoA enzyme activase uncharacterised domain (DUF2229) DUF4559 PF15112.1 AIN97013.1 - 0.6 9.2 19.8 0.012 14.7 7.5 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4559) Flagellar_rod PF05149.7 AIN97015.1 - 6.2e-111 370.2 28.3 6.2e-111 370.2 19.6 1.8 2 0 0 2 2 2 1 Paraflagellar rod protein SpoIISA_toxin PF14171.1 AIN97015.1 - 0.055 12.7 0.8 0.14 11.3 0.6 1.6 1 0 0 1 1 1 0 Toxin SpoIISA, type II toxin-antitoxin system DUF1136 PF06582.7 AIN97015.1 - 0.26 11.0 3.4 0.35 10.5 0.6 2.6 2 0 0 2 2 2 0 Repeat of unknown function (DUF1136) MutS_III PF05192.13 AIN97015.1 - 6.3 6.5 20.0 2.4e+03 -2.0 13.9 3.1 1 1 0 1 1 1 0 MutS domain III PAPS_reduct PF01507.14 AIN97015.1 - 9.4 6.0 14.0 2.4 7.9 2.2 3.1 3 1 0 3 3 3 0 Phosphoadenosine phosphosulfate reductase family DUF3552 PF12072.3 AIN97017.1 - 0.003 16.7 14.0 0.016 14.4 4.6 2.3 2 1 0 2 2 2 2 Domain of unknown function (DUF3552) DUF972 PF06156.8 AIN97017.1 - 0.044 14.1 5.7 1.5 9.2 1.5 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF972) V-SNARE_C PF12352.3 AIN97017.1 - 0.068 13.2 0.9 1.2 9.3 0.3 2.7 2 0 0 2 2 2 0 Snare region anchored in the vesicle membrane C-terminus Laminin_II PF06009.7 AIN97017.1 - 0.076 12.7 9.9 0.084 12.6 4.2 2.3 2 1 0 2 2 2 0 Laminin Domain II Laminin_I PF06008.9 AIN97017.1 - 0.091 12.0 10.0 0.022 14.0 4.4 1.8 2 0 0 2 2 2 0 Laminin Domain I TPR_MLP1_2 PF07926.7 AIN97017.1 - 0.16 11.7 15.3 2.2 8.0 7.4 2.2 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein DUF1993 PF09351.5 AIN97017.1 - 0.22 11.4 7.4 0.25 11.2 1.9 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF1993) Fib_alpha PF08702.5 AIN97017.1 - 0.26 11.4 7.4 2.2 8.4 1.7 2.2 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family Fez1 PF06818.10 AIN97017.1 - 0.27 11.2 10.7 0.2 11.6 6.6 1.4 1 1 0 1 1 1 0 Fez1 COG2 PF06148.6 AIN97017.1 - 0.42 10.4 8.3 0.043 13.6 1.4 2.2 2 1 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Spc7 PF08317.6 AIN97017.1 - 1.4 7.4 12.3 3.4 6.2 4.6 2.1 1 1 0 2 2 2 0 Spc7 kinetochore protein V_ATPase_I PF01496.14 AIN97017.1 - 1.6 6.4 8.4 3.3 5.4 5.8 1.6 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family Sas10_Utp3 PF04000.10 AIN97017.1 - 2 8.6 7.0 15 5.8 5.1 2.5 2 1 0 2 2 2 0 Sas10/Utp3/C1D family OmpH PF03938.9 AIN97017.1 - 3.4 7.6 8.8 5.9 6.8 6.0 1.6 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF4200 PF13863.1 AIN97017.1 - 4.1 7.3 11.0 2.2 8.2 3.5 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) TMF_DNA_bd PF12329.3 AIN97017.1 - 4.5 7.1 14.8 7.3 6.4 8.2 2.4 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding Mnd1 PF03962.10 AIN97017.1 - 4.7 6.8 13.4 1.2 8.7 5.5 2.2 1 1 1 2 2 2 0 Mnd1 family WXG100 PF06013.7 AIN97017.1 - 7 6.7 9.8 29 4.7 3.4 3.2 2 2 0 2 2 2 0 Proteins of 100 residues with WXG DUF1664 PF07889.7 AIN97017.1 - 7.9 6.2 9.4 2.5 7.9 1.9 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Sugarporin_N PF11471.3 AIN97017.1 - 9.1 6.0 11.8 5.4 6.7 2.0 2.5 1 1 1 2 2 2 0 Maltoporin periplasmic N-terminal extension DUF904 PF06005.7 AIN97017.1 - 10 6.5 11.4 24 5.2 5.8 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF904) Kinesin PF00225.18 AIN97018.1 - 1.6e-78 263.7 0.0 3.3e-78 262.7 0.0 1.4 1 0 0 1 1 1 1 Kinesin motor domain Filament PF00038.16 AIN97018.1 - 0.00074 19.0 15.9 0.00074 19.0 11.0 2.2 1 1 1 2 2 2 1 Intermediate filament protein Baculo_PEP_C PF04513.7 AIN97018.1 - 0.0041 16.9 13.7 0.0047 16.7 4.1 3.2 2 1 1 3 3 3 1 Baculovirus polyhedron envelope protein, PEP, C terminus CENP-F_leu_zip PF10473.4 AIN97018.1 - 0.013 15.4 17.2 0.013 15.4 11.9 3.2 2 1 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 AAA_13 PF13166.1 AIN97018.1 - 0.071 11.5 12.2 0.031 12.7 6.5 1.8 1 1 0 1 1 1 0 AAA domain Spc7 PF08317.6 AIN97018.1 - 0.14 10.7 23.4 0.13 10.9 1.1 3.2 1 1 2 3 3 3 0 Spc7 kinetochore protein Reo_sigmaC PF04582.7 AIN97018.1 - 2.6 7.1 8.2 18 4.4 2.9 3.1 2 1 1 3 3 3 0 Reovirus sigma C capsid protein TPR_MLP1_2 PF07926.7 AIN97018.1 - 3.1 7.5 27.1 0.1 12.3 6.5 3.4 1 1 2 3 3 3 0 TPR/MLP1/MLP2-like protein DUF1664 PF07889.7 AIN97018.1 - 3.4 7.4 11.9 5.7 6.7 2.9 3.5 1 1 2 4 4 4 0 Protein of unknown function (DUF1664) DUF972 PF06156.8 AIN97018.1 - 4.2 7.7 24.1 26 5.2 4.6 4.5 3 1 1 4 4 4 0 Protein of unknown function (DUF972) Pox_A_type_inc PF04508.7 AIN97018.1 - 4.3 7.3 18.4 0.048 13.4 0.5 4.6 4 0 0 4 4 4 0 Viral A-type inclusion protein repeat DASH_Hsk3 PF08227.6 AIN97018.1 - 7.2 6.8 7.2 18 5.5 0.5 3.2 2 0 0 2 2 2 0 DASH complex subunit Hsk3 like IncA PF04156.9 AIN97018.1 - 7.2 6.1 36.6 4.3 6.8 11.9 3.2 1 1 1 3 3 3 0 IncA protein Laminin_I PF06008.9 AIN97019.1 - 0.00022 20.6 11.3 0.00022 20.6 7.8 1.8 2 0 0 2 2 2 1 Laminin Domain I DUF3552 PF12072.3 AIN97019.1 - 0.00076 18.7 20.9 0.0036 16.5 7.9 2.4 2 1 0 2 2 2 2 Domain of unknown function (DUF3552) V-SNARE_C PF12352.3 AIN97019.1 - 0.0044 17.0 2.2 0.14 12.2 0.7 3.3 2 1 1 3 3 3 1 Snare region anchored in the vesicle membrane C-terminus Laminin_II PF06009.7 AIN97019.1 - 0.024 14.4 13.7 0.18 11.5 6.7 3.1 2 2 1 3 3 3 0 Laminin Domain II Spc7 PF08317.6 AIN97019.1 - 0.032 12.8 15.7 0.12 11.0 6.8 2.1 2 0 0 2 2 2 0 Spc7 kinetochore protein TPR_MLP1_2 PF07926.7 AIN97019.1 - 0.05 13.3 20.3 0.49 10.1 10.0 2.2 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein MscS_porin PF12795.2 AIN97019.1 - 0.061 12.6 15.7 0.11 11.7 10.9 1.4 1 0 0 1 1 1 0 Mechanosensitive ion channel porin domain Fez1 PF06818.10 AIN97019.1 - 0.085 12.8 15.2 0.046 13.7 9.2 1.4 1 1 0 1 1 1 0 Fez1 DUF3407 PF11887.3 AIN97019.1 - 0.2 10.8 3.7 0.25 10.6 2.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3407) Tropomyosin PF00261.15 AIN97019.1 - 0.37 9.8 20.3 0.024 13.7 8.1 2.2 2 0 0 2 2 2 0 Tropomyosin MCPsignal PF00015.16 AIN97019.1 - 0.42 10.1 19.4 0.29 10.6 7.4 2.1 1 1 1 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain Fib_alpha PF08702.5 AIN97019.1 - 0.5 10.4 11.2 0.82 9.7 3.1 2.3 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family V_ATPase_I PF01496.14 AIN97019.1 - 1.1 7.0 11.2 2.5 5.8 7.7 1.6 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family IFT57 PF10498.4 AIN97019.1 - 1.1 7.8 13.5 0.87 8.2 4.5 2.3 1 1 1 2 2 2 0 Intra-flagellar transport protein 57 DUF4200 PF13863.1 AIN97019.1 - 1.4 8.8 16.5 3.6 7.5 7.2 3.1 2 2 0 2 2 2 0 Domain of unknown function (DUF4200) Sec20 PF03908.8 AIN97019.1 - 1.6 8.5 9.3 4.7 6.9 3.8 2.8 2 1 0 2 2 2 0 Sec20 WXG100 PF06013.7 AIN97019.1 - 1.6 8.8 15.4 2e+02 2.0 0.1 3.8 2 2 0 2 2 2 0 Proteins of 100 residues with WXG Synaptobrevin PF00957.16 AIN97019.1 - 1.9 8.1 6.5 2.8 7.6 1.5 2.8 2 1 1 3 3 3 0 Synaptobrevin DUF972 PF06156.8 AIN97019.1 - 2.1 8.7 13.5 13 6.2 0.1 3.0 2 1 0 2 2 2 0 Protein of unknown function (DUF972) Reo_sigmaC PF04582.7 AIN97019.1 - 2.2 7.3 11.1 0.35 9.9 4.1 1.9 1 1 1 2 2 2 0 Reovirus sigma C capsid protein TMPIT PF07851.8 AIN97019.1 - 2.5 7.1 7.8 0.49 9.4 2.0 1.9 2 0 0 2 2 2 0 TMPIT-like protein COG2 PF06148.6 AIN97019.1 - 2.6 7.9 14.1 0.14 12.0 2.5 3.0 2 2 2 4 4 4 0 COG (conserved oligomeric Golgi) complex component, COG2 TMF_DNA_bd PF12329.3 AIN97019.1 - 3.4 7.5 22.5 25 4.7 10.2 3.0 2 1 0 2 2 2 0 TATA element modulatory factor 1 DNA binding DUF1993 PF09351.5 AIN97019.1 - 3.6 7.4 13.1 15 5.4 5.5 3.0 1 1 1 2 2 2 0 Domain of unknown function (DUF1993) FemAB PF02388.11 AIN97019.1 - 3.9 6.0 7.8 3.3 6.2 4.8 1.4 1 1 0 1 1 1 0 FemAB family Filament PF00038.16 AIN97019.1 - 4.3 6.7 19.5 0.26 10.6 8.8 2.0 2 0 0 2 2 2 0 Intermediate filament protein Sas10_Utp3 PF04000.10 AIN97019.1 - 5.1 7.3 16.1 13 6.0 4.7 3.2 2 1 1 3 3 3 0 Sas10/Utp3/C1D family Prominin PF05478.6 AIN97019.1 - 6 4.2 9.0 7.9 3.8 6.2 1.2 1 0 0 1 1 1 0 Prominin Sugarporin_N PF11471.3 AIN97019.1 - 6 6.5 19.2 4.7 6.9 2.5 3.4 1 1 2 3 3 3 0 Maltoporin periplasmic N-terminal extension OmpH PF03938.9 AIN97019.1 - 6.8 6.6 15.4 23 4.8 10.5 2.1 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF904 PF06005.7 AIN97019.1 - 7 7.0 15.1 3.6e+02 1.5 0.0 3.3 2 1 0 2 2 2 0 Protein of unknown function (DUF904) UPF0449 PF15136.1 AIN97019.1 - 8.9 6.5 8.8 14 5.9 2.6 3.2 2 2 0 2 2 2 0 Uncharacterised protein family UPF0449 zf-met2 PF12907.2 AIN97023.1 - 0.12 12.4 4.4 1.7 8.6 0.1 2.4 2 0 0 2 2 2 0 Zinc-binding ERO1 PF04137.10 AIN97025.1 - 1.1e-95 320.6 0.0 1.3e-95 320.4 0.0 1.0 1 0 0 1 1 1 1 Endoplasmic Reticulum Oxidoreductin 1 (ERO1) DNA_pol_B PF00136.16 AIN97026.1 - 1e-120 403.6 0.0 1.5e-120 403.1 0.0 1.1 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.14 AIN97026.1 - 1.7e-34 119.1 0.0 3e-34 118.3 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain zf-DNA_Pol PF08996.5 AIN97026.1 - 0.022 14.1 2.6 0.36 10.1 1.7 2.4 2 0 0 2 2 2 0 DNA Polymerase alpha zinc finger WD40 PF00400.27 AIN97027.1 - 7e-24 82.7 4.5 5.4e-06 26.0 0.1 6.3 6 0 0 6 6 6 4 WD domain, G-beta repeat gpW PF02831.10 AIN97027.1 - 0.013 15.0 3.5 0.19 11.3 0.1 3.4 2 1 1 3 3 3 0 gpW KIP1 PF07765.7 AIN97027.1 - 0.087 12.6 5.6 0.14 12.0 0.5 3.4 3 0 0 3 3 3 0 KIP1-like protein Peptidase_M61 PF05299.7 AIN97027.1 - 0.14 12.1 2.1 2.1 8.3 0.1 2.6 2 0 0 2 2 2 0 M61 glycyl aminopeptidase PPR_3 PF13812.1 AIN97028.1 - 0.017 15.3 3.0 56 4.3 0.0 5.4 5 0 0 5 5 5 0 Pentatricopeptide repeat domain RRN3 PF05327.6 AIN97028.1 - 0.036 12.1 0.1 2.9 5.9 0.0 2.1 2 0 0 2 2 2 0 RNA polymerase I specific transcription initiation factor RRN3 Kinesin PF00225.18 AIN97030.1 - 4e-69 232.8 0.0 1.7e-40 138.7 0.0 2.3 2 0 0 2 2 2 2 Kinesin motor domain GRIM-19 PF06212.7 AIN97030.1 - 0.1 12.3 0.0 0.26 10.9 0.0 1.7 1 0 0 1 1 1 0 GRIM-19 protein RRM_6 PF14259.1 AIN97031.1 - 8.1e-17 60.9 0.1 1.4e-16 60.1 0.1 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 AIN97031.1 - 9.8e-15 53.9 0.0 1.6e-14 53.2 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 AIN97031.1 - 1.2e-06 28.2 0.1 2.4e-06 27.2 0.1 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 AIN97031.1 - 0.1 12.3 0.0 0.2 11.4 0.0 1.5 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif MIF4G PF02854.14 AIN97032.1 - 2.2e-26 92.5 1.2 3.1e-26 92.0 0.8 1.2 1 0 0 1 1 1 1 MIF4G domain Band_7 PF01145.20 AIN97033.1 - 5.2e-22 78.6 3.9 6.1e-22 78.3 2.0 1.6 1 1 1 2 2 2 1 SPFH domain / Band 7 family DUF4200 PF13863.1 AIN97033.1 - 0.016 15.1 2.7 0.016 15.1 1.9 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) Col_cuticle_N PF01484.12 AIN97033.1 - 0.29 10.8 4.2 0.26 11.0 1.5 2.0 2 1 0 2 2 2 0 Nematode cuticle collagen N-terminal domain WD40 PF00400.27 AIN97034.1 - 0.01 15.6 5.0 0.87 9.5 0.0 3.5 3 0 0 3 3 3 0 WD domain, G-beta repeat Nop PF01798.13 AIN97035.1 - 1.3e-09 37.5 0.6 4.2e-09 35.8 0.4 1.9 1 1 0 1 1 1 1 Putative snoRNA binding domain Prp31_C PF09785.4 AIN97035.1 - 0.019 15.3 2.8 0.019 15.3 1.9 1.7 2 0 0 2 2 2 0 Prp31 C terminal domain UPF0137 PF03677.8 AIN97035.1 - 0.076 12.5 0.4 0.97 8.9 0.2 2.0 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0137) CLU PF13236.1 AIN97036.1 - 2.5e-08 33.6 0.0 1.2e-06 28.1 0.0 2.4 1 1 0 1 1 1 1 Clustered mitochondria eIF3_p135 PF12807.2 AIN97036.1 - 2.6e-06 27.5 0.0 4.4e-06 26.7 0.0 1.3 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit 135 TPR_11 PF13414.1 AIN97037.1 - 0.00057 19.4 0.7 0.073 12.7 0.1 3.5 2 1 1 3 3 3 1 TPR repeat TPR_2 PF07719.12 AIN97037.1 - 0.0046 16.7 4.1 0.13 12.2 0.0 4.3 4 0 0 4 4 4 1 Tetratricopeptide repeat CLU PF13236.1 AIN97037.1 - 0.0055 16.1 0.1 0.084 12.2 0.1 2.2 1 1 0 1 1 1 1 Clustered mitochondria eIF3_p135 PF12807.2 AIN97037.1 - 0.0077 16.1 0.0 0.016 15.1 0.0 1.4 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit 135 TPR_12 PF13424.1 AIN97037.1 - 0.011 15.6 8.2 2.5 8.0 0.2 4.5 3 1 2 5 5 5 0 Tetratricopeptide repeat DUF2300 PF10062.4 AIN97038.1 - 0.053 13.2 0.4 0.31 10.7 0.1 2.4 2 0 0 2 2 2 0 Predicted secreted protein (DUF2300) DUF3522 PF12036.3 AIN97040.1 - 2.3e-64 216.6 11.4 2.8e-64 216.3 7.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3522) DUF3784 PF12650.2 AIN97040.1 - 0.081 12.8 0.4 0.081 12.8 0.3 2.8 2 1 2 4 4 4 0 Domain of unknown function (DUF3784) Cytochrom_B561 PF03188.11 AIN97040.1 - 0.081 12.7 10.4 0.22 11.3 0.1 3.4 2 2 1 3 3 3 0 Eukaryotic cytochrome b561 DUF4401 PF14351.1 AIN97040.1 - 0.23 10.4 11.5 0.12 11.3 5.9 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4401) Yip1 PF04893.12 AIN97040.1 - 7.7 5.9 9.2 0.37 10.2 0.5 2.8 2 2 0 2 2 2 0 Yip1 domain zf-RING_2 PF13639.1 AIN97041.1 - 2.1e-11 43.4 8.0 4.8e-11 42.3 5.5 1.7 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 AIN97041.1 - 9.8e-09 35.2 5.9 2.8e-08 33.7 4.1 1.9 1 1 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 AIN97041.1 - 1.2e-08 34.8 6.9 2.6e-08 33.7 4.8 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 AIN97041.1 - 8.8e-08 31.6 7.0 1.7e-07 30.7 4.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 AIN97041.1 - 1.3e-07 31.1 3.6 2.8e-07 30.1 2.5 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 AIN97041.1 - 7.9e-06 25.5 5.0 1.6e-05 24.5 3.5 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-Apc11 PF12861.2 AIN97041.1 - 1.3e-05 24.9 1.6 2.7e-05 23.9 1.1 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_4 PF15227.1 AIN97041.1 - 2.5e-05 24.0 6.4 5.4e-05 22.9 4.4 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 AIN97041.1 - 0.00014 21.4 6.7 0.0003 20.4 4.6 1.5 1 0 0 1 1 1 1 RING-type zinc-finger CpXC PF14353.1 AIN97041.1 - 0.0011 18.9 0.2 0.0018 18.2 0.1 1.3 1 0 0 1 1 1 1 CpXC protein zf-RING_6 PF14835.1 AIN97041.1 - 0.028 14.1 2.3 0.08 12.7 1.2 2.1 1 1 1 2 2 2 0 zf-RING of BARD1-type protein zf-Nse PF11789.3 AIN97041.1 - 0.087 12.3 3.2 0.22 11.0 2.2 1.7 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit RINGv PF12906.2 AIN97041.1 - 0.17 11.9 4.2 0.51 10.4 2.9 1.9 1 1 0 1 1 1 0 RING-variant domain FANCL_C PF11793.3 AIN97041.1 - 0.29 11.1 6.9 3.6 7.6 4.8 2.8 1 1 1 2 2 2 0 FANCL C-terminal domain Prok-RING_4 PF14447.1 AIN97041.1 - 1.5 8.4 6.3 3.1 7.3 0.2 2.6 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 DnaJ PF00226.26 AIN97042.1 - 3.8e-07 29.7 0.0 6.2e-07 29.0 0.0 1.3 1 0 0 1 1 1 1 DnaJ domain RRM_5 PF13893.1 AIN97043.1 - 0.0016 18.2 0.0 0.0042 16.9 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) NAGidase PF07555.8 AIN97043.1 - 0.018 14.0 0.3 0.032 13.1 0.1 1.5 2 0 0 2 2 2 0 beta-N-acetylglucosaminidase GCR1_C PF12550.3 AIN97043.1 - 0.14 12.0 3.0 0.31 10.9 1.8 1.9 1 1 0 1 1 1 0 Transcriptional activator of glycolytic enzymes PsaN PF05479.6 AIN97043.1 - 0.98 9.3 3.6 0.63 10.0 1.3 1.6 2 1 0 2 2 2 0 Photosystem I reaction centre subunit N (PSAN or PSI-N) Pkinase PF00069.20 AIN97044.1 - 2.2e-63 213.8 0.0 2.8e-63 213.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AIN97044.1 - 1.3e-37 129.2 0.0 1.9e-37 128.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase LRR_4 PF12799.2 AIN97044.1 - 3.7e-06 26.4 0.2 1.2e-05 24.8 0.1 1.9 1 0 0 1 1 1 1 Leucine Rich repeats (2 copies) LRR_6 PF13516.1 AIN97044.1 - 4.1e-05 23.2 2.5 1.7 8.9 0.0 3.9 4 0 0 4 4 4 2 Leucine Rich repeat Kinase-like PF14531.1 AIN97044.1 - 0.00012 21.1 0.0 0.00019 20.4 0.0 1.2 1 0 0 1 1 1 1 Kinase-like LRR_8 PF13855.1 AIN97044.1 - 0.00077 19.1 0.9 0.002 17.8 0.6 1.7 1 0 0 1 1 1 1 Leucine rich repeat LRR_1 PF00560.28 AIN97044.1 - 0.0021 17.8 1.6 3 8.2 0.1 3.2 3 0 0 3 3 3 2 Leucine Rich Repeat RIO1 PF01163.17 AIN97044.1 - 0.0031 16.8 0.0 0.0063 15.8 0.0 1.4 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.9 AIN97044.1 - 0.03 13.3 0.0 0.055 12.5 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family zf-RING_2 PF13639.1 AIN97044.1 - 0.13 12.1 2.9 0.41 10.4 0.0 2.9 3 0 0 3 3 3 0 Ring finger domain Arf PF00025.16 AIN97045.1 - 7e-68 227.2 0.1 8.4e-68 227.0 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 AIN97045.1 - 1.4e-11 43.9 0.0 1.7e-11 43.6 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.17 AIN97045.1 - 8.8e-11 41.4 0.0 1.1e-10 41.2 0.0 1.1 1 0 0 1 1 1 1 Ras family G-alpha PF00503.15 AIN97045.1 - 6e-10 38.3 0.3 1.2e-07 30.8 0.0 2.2 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.7 AIN97045.1 - 1.6e-09 37.3 0.0 1.9e-09 37.0 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 AIN97045.1 - 4.9e-07 30.2 0.0 7.2e-07 29.7 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 AIN97045.1 - 2.3e-06 27.5 0.0 3.1e-06 27.1 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase AP_endonuc_2 PF01261.19 AIN97045.1 - 0.0027 17.0 0.0 0.0057 15.9 0.0 1.4 1 1 0 1 1 1 1 Xylose isomerase-like TIM barrel FeoB_N PF02421.13 AIN97045.1 - 0.01 15.0 0.5 0.087 12.0 0.4 2.0 1 1 0 1 1 1 0 Ferrous iron transport protein B GTP_EFTU PF00009.22 AIN97046.1 - 5.3e-54 182.5 0.0 9.7e-54 181.6 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 AIN97046.1 - 1.3e-35 121.5 0.1 5.2e-35 119.5 0.0 2.0 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 AIN97046.1 - 1.3e-18 66.8 0.7 1.3e-18 66.8 0.5 2.0 2 0 0 2 2 2 1 Elongation factor Tu domain 2 GTP_EFTU_D4 PF14578.1 AIN97046.1 - 5e-06 26.0 0.3 1.5e-05 24.5 0.2 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 4 MMR_HSR1 PF01926.18 AIN97046.1 - 4.1e-05 23.5 0.0 0.00015 21.7 0.0 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.5 AIN97046.1 - 0.0032 16.7 0.1 0.021 14.0 0.0 2.3 1 1 1 2 2 2 1 Signal recognition particle receptor beta subunit Miro PF08477.8 AIN97046.1 - 0.0045 17.4 0.3 0.046 14.2 0.2 2.3 1 1 0 1 1 1 1 Miro-like protein Semialdhyde_dhC PF02774.13 AIN97046.1 - 0.073 12.9 0.3 0.62 9.8 0.1 2.1 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, dimerisation domain Guanylate_cyc PF00211.15 AIN97047.1 - 5.1e-37 127.0 0.0 8.9e-37 126.2 0.0 1.4 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain Guanylate_cyc PF00211.15 AIN97048.1 - 4e-37 127.3 0.0 8.9e-37 126.2 0.0 1.6 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain DUF1640 PF07798.6 AIN97051.1 - 0.2 11.6 16.0 0.16 11.9 7.4 2.8 2 2 0 2 2 2 0 Protein of unknown function (DUF1640) TMPIT PF07851.8 AIN97051.1 - 9.4 5.1 5.8 18 4.2 4.0 1.5 1 0 0 1 1 1 0 TMPIT-like protein TPR_2 PF07719.12 AIN97052.1 - 5.3e-17 60.2 1.6 0.00023 20.8 0.0 4.5 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_11 PF13414.1 AIN97052.1 - 2.4e-13 49.4 2.1 4.6e-06 26.1 0.9 2.5 2 0 0 2 2 2 2 TPR repeat TPR_8 PF13181.1 AIN97052.1 - 1.1e-08 34.2 7.0 0.17 11.7 0.6 5.2 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_12 PF13424.1 AIN97052.1 - 1.6e-08 34.3 6.5 0.0049 16.7 1.3 4.2 1 1 3 4 4 4 3 Tetratricopeptide repeat TPR_1 PF00515.23 AIN97052.1 - 5.3e-08 32.1 6.6 0.0097 15.4 0.0 4.5 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_17 PF13431.1 AIN97052.1 - 1.3e-06 28.1 1.1 2.6 8.4 0.1 4.6 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_6 PF13174.1 AIN97052.1 - 4.4e-06 26.7 0.3 0.16 12.4 0.0 4.8 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_14 PF13428.1 AIN97052.1 - 1.3e-05 25.3 0.1 4.8 8.1 0.0 4.4 4 1 1 5 5 3 2 Tetratricopeptide repeat TPR_19 PF14559.1 AIN97052.1 - 2e-05 24.8 0.4 0.0012 19.0 0.0 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.1 AIN97052.1 - 4.3e-05 24.0 0.1 0.12 13.0 0.0 4.1 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_10 PF13374.1 AIN97052.1 - 6.8e-05 22.6 1.9 1.2 9.1 0.0 3.9 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.1 AIN97052.1 - 0.00014 21.4 6.9 0.031 14.0 0.0 4.3 5 0 0 5 5 4 2 Tetratricopeptide repeat Apc3 PF12895.2 AIN97052.1 - 0.00079 19.5 6.4 0.004 17.2 0.0 3.1 1 1 3 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 DUF896 PF05979.7 AIN97053.1 - 0.27 10.8 1.6 0.65 9.6 1.1 1.6 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF896) Peptidase_M20 PF01546.23 AIN97054.1 - 9.8e-14 51.2 0.1 1.6e-13 50.6 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 AIN97054.1 - 8.2e-11 41.6 0.0 1.5e-09 37.5 0.0 2.3 2 0 0 2 2 2 1 Peptidase dimerisation domain Peptidase_M42 PF05343.9 AIN97054.1 - 3.7e-06 25.9 0.1 4.8e-05 22.2 0.1 2.3 2 0 0 2 2 2 1 M42 glutamyl aminopeptidase Peptidase_M28 PF04389.12 AIN97054.1 - 2.1e-05 24.3 0.0 4.8e-05 23.1 0.0 1.6 1 0 0 1 1 1 1 Peptidase family M28 Kinesin PF00225.18 AIN97056.1 - 4.2e-40 137.4 0.0 9.6e-25 86.9 0.0 2.2 2 0 0 2 2 2 2 Kinesin motor domain WD40 PF00400.27 AIN97057.1 - 8.5e-33 111.0 12.7 4.8e-09 35.7 0.3 5.8 5 0 0 5 5 5 4 WD domain, G-beta repeat Nup160 PF11715.3 AIN97057.1 - 0.00019 19.7 0.6 0.045 11.8 0.0 3.2 1 1 1 2 2 2 2 Nucleoporin Nup120/160 PD40 PF07676.7 AIN97057.1 - 0.00038 20.0 0.0 1.6 8.4 0.0 3.9 4 0 0 4 4 4 2 WD40-like Beta Propeller Repeat eIF2A PF08662.6 AIN97057.1 - 0.0029 17.3 0.0 0.19 11.4 0.0 2.2 1 1 1 2 2 2 1 Eukaryotic translation initiation factor eIF2A DUF3312 PF11768.3 AIN97057.1 - 0.0052 15.0 0.0 0.0083 14.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3312) Proteasome_A_N PF10584.4 AIN97057.1 - 0.079 12.2 0.1 5.2 6.4 0.0 2.8 2 0 0 2 2 2 0 Proteasome subunit A N-terminal signature PQQ_2 PF13360.1 AIN97057.1 - 0.21 11.0 0.0 9.5 5.5 0.0 2.3 2 0 0 2 2 2 0 PQQ-like domain RCC1 PF00415.13 AIN97058.1 - 4.5e-50 167.6 41.1 1e-13 51.2 0.7 8.8 7 2 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 AIN97058.1 - 1.5e-32 110.4 49.2 6.2e-12 44.7 2.8 8.3 9 0 0 9 9 9 6 Regulator of chromosome condensation (RCC1) repeat BTB_2 PF02214.17 AIN97058.1 - 1.5e-06 28.3 0.0 0.052 13.7 0.0 2.3 2 0 0 2 2 2 2 BTB/POZ domain CBM_X PF06204.6 AIN97058.1 - 2.5 7.6 4.8 49 3.4 0.5 3.5 3 0 0 3 3 3 0 Putative carbohydrate binding domain PALP PF00291.20 AIN97059.1 - 3.3e-60 203.8 0.1 3.9e-60 203.6 0.1 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Bmp PF02608.9 AIN97059.1 - 0.012 14.3 0.0 0.36 9.5 0.0 2.2 1 1 1 2 2 2 0 Basic membrane protein DUF1150 PF06620.6 AIN97060.1 - 0.047 13.5 0.0 3.8 7.3 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1150) 2Fe-2S_thioredx PF01257.14 AIN97061.1 - 2.1e-48 163.6 0.0 2.7e-48 163.2 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin-like [2Fe-2S] ferredoxin Histone PF00125.19 AIN97062.1 - 1.2e-15 57.3 0.2 1.7e-15 56.8 0.1 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 zf-C3HC4_2 PF13923.1 AIN97063.1 - 3.7e-07 30.0 16.3 3.7e-07 30.0 11.3 3.9 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 AIN97063.1 - 2.5e-05 23.8 17.8 2.5e-05 23.8 12.3 3.4 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 AIN97063.1 - 5e-05 22.8 13.8 5e-05 22.8 9.6 3.1 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 AIN97063.1 - 0.0011 18.8 15.5 0.0011 18.8 10.7 2.5 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.1 AIN97063.1 - 0.0021 17.8 18.7 0.0021 17.8 13.0 4.1 5 0 0 5 5 5 1 Ring finger domain zf-RING_5 PF14634.1 AIN97063.1 - 0.0026 17.4 14.4 0.0026 17.4 10.0 3.4 3 0 0 3 3 3 1 zinc-RING finger domain LSM PF01423.17 AIN97064.1 - 7.7e-05 22.1 0.0 0.00031 20.2 0.0 1.8 1 1 0 1 1 1 1 LSM domain dsrm PF00035.20 AIN97067.1 - 0.0007 20.1 0.0 2.5 8.7 0.0 2.8 2 0 0 2 2 2 2 Double-stranded RNA binding motif Dus PF01207.12 AIN97069.1 - 2.4e-49 167.8 0.0 4.1e-49 167.0 0.0 1.3 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) GLYCAM-1 PF05242.6 AIN97069.1 - 0.15 12.0 5.7 0.37 10.7 3.5 1.9 2 0 0 2 2 2 0 Glycosylation-dependent cell adhesion molecule 1 (GlyCAM-1) DUF4105 PF13387.1 AIN97069.1 - 0.18 10.9 0.0 0.3 10.2 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4105) dCMP_cyt_deam_1 PF00383.17 AIN97070.1 - 1.9e-12 46.7 2.8 2.8e-12 46.1 2.0 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region dCMP_cyt_deam_2 PF08211.6 AIN97070.1 - 1.1e-08 35.0 1.3 1.4e-06 28.3 0.5 2.2 2 0 0 2 2 2 2 Cytidine and deoxycytidylate deaminase zinc-binding region LmjF365940-deam PF14421.1 AIN97070.1 - 0.0031 16.9 2.0 0.092 12.1 0.0 2.0 1 1 1 2 2 2 2 A distinct subfamily of CDD/CDA-like deaminases Thioredoxin PF00085.15 AIN97070.1 - 0.13 11.9 0.0 0.22 11.2 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin Fer4_15 PF13459.1 AIN97070.1 - 0.57 10.7 4.3 4 8.0 0.1 2.4 2 0 0 2 2 2 0 4Fe-4S single cluster domain Pheromone PF08015.6 AIN97071.1 - 0.024 15.4 2.0 0.024 15.4 1.4 4.8 5 1 1 6 6 6 0 Fungal mating-type pheromone Sec20 PF03908.8 AIN97072.1 - 0.00011 21.7 1.8 0.00011 21.7 1.3 1.9 2 0 0 2 2 2 1 Sec20 MtrG PF04210.8 AIN97072.1 - 0.0066 16.1 0.4 0.018 14.7 0.3 1.7 1 0 0 1 1 1 1 Tetrahydromethanopterin S-methyltransferase, subunit G V-SNARE_C PF12352.3 AIN97072.1 - 0.0092 16.0 2.6 0.023 14.7 1.8 1.8 1 0 0 1 1 1 1 Snare region anchored in the vesicle membrane C-terminus Cep57_MT_bd PF06657.8 AIN97072.1 - 0.067 13.1 3.5 0.48 10.3 0.0 3.2 3 0 0 3 3 3 0 Centrosome microtubule-binding domain of Cep57 Med11 PF10280.4 AIN97072.1 - 0.07 13.1 1.6 0.12 12.3 0.0 2.0 2 1 0 2 2 2 0 Mediator complex protein DUF16 PF01519.11 AIN97072.1 - 0.17 12.1 0.7 0.39 10.9 0.5 1.5 1 0 0 1 1 1 0 Protein of unknown function DUF16 Spore_III_AB PF09548.5 AIN97072.1 - 0.32 10.7 3.5 3 7.5 0.1 2.5 3 0 0 3 3 3 0 Stage III sporulation protein AB (spore_III_AB) V-SNARE PF05008.10 AIN97072.1 - 0.81 9.8 5.3 0.5 10.5 0.1 2.5 2 1 0 2 2 2 0 Vesicle transport v-SNARE protein N-terminus KxDL PF10241.4 AIN97072.1 - 1.9 8.4 8.3 0.8 9.6 1.7 2.4 2 0 0 2 2 2 0 Uncharacterized conserved protein CENP-H PF05837.7 AIN97072.1 - 6.2 7.0 8.6 1.1 9.4 2.5 2.1 2 0 0 2 2 2 0 Centromere protein H (CENP-H) Pkinase PF00069.20 AIN97073.1 - 1.3e-58 198.2 0.0 2.4e-58 197.3 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AIN97073.1 - 1.8e-39 135.3 0.0 4.9e-38 130.6 0.0 2.1 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 AIN97073.1 - 8e-08 31.5 0.0 1.9e-07 30.3 0.0 1.5 1 1 1 2 2 2 1 Kinase-like ANTH PF07651.11 AIN97073.1 - 0.0045 15.7 0.0 0.0097 14.6 0.0 1.5 1 0 0 1 1 1 1 ANTH domain APH PF01636.18 AIN97073.1 - 0.0074 16.0 0.0 0.016 14.9 0.0 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 AIN97073.1 - 0.013 14.5 0.0 0.024 13.7 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family zf-RING_2 PF13639.1 AIN97074.1 - 5e-11 42.2 4.5 5e-11 42.2 3.1 2.5 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.20 AIN97074.1 - 3.6e-05 23.3 3.2 3.6e-05 23.3 2.2 2.6 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 AIN97074.1 - 0.00011 22.0 4.7 0.00011 22.0 3.3 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 AIN97074.1 - 0.00023 20.8 5.9 0.00023 20.8 4.1 1.9 2 0 0 2 2 2 1 zinc-RING finger domain zf-rbx1 PF12678.2 AIN97074.1 - 0.00098 19.1 0.6 0.00098 19.1 0.4 2.2 2 0 0 2 2 2 1 RING-H2 zinc finger zf-C3HC4_4 PF15227.1 AIN97074.1 - 0.0081 16.0 4.0 0.0081 16.0 2.8 3.2 2 1 0 2 2 2 1 zinc finger of C3HC4-type, RING CbiN PF02553.10 AIN97074.1 - 0.014 15.4 0.0 0.037 14.0 0.0 1.7 1 0 0 1 1 1 0 Cobalt transport protein component CbiN zf-Nse PF11789.3 AIN97074.1 - 0.025 14.0 3.4 0.059 12.9 2.4 1.6 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit DUF1249 PF06853.7 AIN97074.1 - 0.1 12.2 0.0 0.23 11.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1249) Nucleo_P87 PF07267.6 AIN97075.1 - 4.7 5.7 6.5 11 4.5 4.5 1.5 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 N6-adenineMlase PF10237.4 AIN97076.1 - 3.5e-42 143.8 1.4 5.7e-42 143.1 0.9 1.3 1 0 0 1 1 1 1 Probable N6-adenine methyltransferase Methyltransf_26 PF13659.1 AIN97076.1 - 0.047 13.7 0.5 0.15 12.1 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase domain Muted PF14942.1 AIN97076.1 - 1.1 9.1 8.5 0.33 10.8 0.1 3.0 3 0 0 3 3 3 0 Organelle biogenesis, Muted-like protein DUF3138 PF11336.3 AIN97076.1 - 1.2 7.2 5.3 2 6.4 3.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) Spc7 PF08317.6 AIN97078.1 - 0.1 11.2 3.0 0.23 10.0 2.1 1.5 1 0 0 1 1 1 0 Spc7 kinetochore protein BLOC1_2 PF10046.4 AIN97078.1 - 0.23 11.6 0.7 0.67 10.1 0.5 1.8 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DnaJ PF00226.26 AIN97080.1 - 1.3e-11 44.0 0.0 2.4e-11 43.1 0.0 1.5 1 0 0 1 1 1 1 DnaJ domain PhzC-PhzF PF02567.11 AIN97082.1 - 4.1e-36 124.6 1.9 7e-24 84.5 0.0 5.0 4 1 0 4 4 4 3 Phenazine biosynthesis-like protein Sigma70_r4 PF04545.11 AIN97082.1 - 0.011 15.0 0.1 0.022 14.0 0.0 1.5 1 0 0 1 1 1 0 Sigma-70, region 4 DUF3940 PF13076.1 AIN97082.1 - 0.13 11.8 0.1 0.27 10.8 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3940) Pkinase PF00069.20 AIN97083.1 - 6.4e-58 195.9 0.0 8.5e-58 195.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AIN97083.1 - 2.4e-39 134.9 0.0 1.5e-38 132.4 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase TFIIA PF03153.8 AIN97083.1 - 0.0001 22.3 9.4 0.00021 21.3 6.5 1.5 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Kinase-like PF14531.1 AIN97083.1 - 0.0015 17.5 0.0 0.0035 16.3 0.0 1.6 1 0 0 1 1 1 1 Kinase-like TFIIF_alpha PF05793.7 AIN97083.1 - 0.017 13.5 17.0 0.029 12.7 11.8 1.4 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) CDC45 PF02724.9 AIN97083.1 - 0.57 8.1 21.1 0.88 7.5 14.6 1.2 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.7 AIN97083.1 - 0.64 7.8 27.5 0.96 7.2 19.1 1.1 1 0 0 1 1 1 0 Nop14-like family Daxx PF03344.10 AIN97083.1 - 0.88 7.9 21.7 1.5 7.2 15.0 1.2 1 0 0 1 1 1 0 Daxx Family SDA1 PF05285.7 AIN97083.1 - 2 7.5 26.1 3.3 6.9 18.1 1.2 1 0 0 1 1 1 0 SDA1 Trypan_PARP PF05887.6 AIN97083.1 - 6.1 6.6 14.5 5.2 6.8 8.3 2.1 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) BUD22 PF09073.5 AIN97083.1 - 9.2 5.2 30.6 15 4.4 21.2 1.2 1 0 0 1 1 1 0 BUD22 AAA PF00004.24 AIN97088.1 - 1.7e-09 37.9 0.1 4.3e-08 33.4 0.0 2.4 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.10 AIN97088.1 - 5.2e-06 25.4 0.0 0.0042 15.8 0.0 2.6 3 0 0 3 3 3 2 Rad17 cell cycle checkpoint protein AAA_19 PF13245.1 AIN97088.1 - 9.2e-06 25.3 2.2 4.7e-05 23.0 1.5 2.3 1 0 0 1 1 1 1 Part of AAA domain AAA_17 PF13207.1 AIN97088.1 - 9.9e-06 26.3 0.1 2.6e-05 25.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 AIN97088.1 - 1.2e-05 25.4 0.0 3.7e-05 23.8 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 AIN97088.1 - 5.8e-05 23.1 0.1 5.8e-05 23.1 0.0 2.6 3 0 0 3 3 3 1 AAA ATPase domain AAA_5 PF07728.9 AIN97088.1 - 7.1e-05 22.5 0.0 0.0013 18.4 0.0 2.9 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_28 PF13521.1 AIN97088.1 - 7.9e-05 22.6 0.1 0.00022 21.1 0.1 1.8 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 AIN97088.1 - 0.00035 20.8 0.0 0.001 19.3 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 AIN97088.1 - 0.00065 19.5 0.1 0.0033 17.3 0.0 2.3 2 0 0 2 2 1 1 AAA domain RuvB_N PF05496.7 AIN97088.1 - 0.0015 17.6 0.1 0.0027 16.7 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus NTPase_1 PF03266.10 AIN97088.1 - 0.0022 17.6 0.1 0.005 16.5 0.0 1.5 1 0 0 1 1 1 1 NTPase DUF258 PF03193.11 AIN97088.1 - 0.0029 16.8 0.0 0.0061 15.7 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_25 PF13481.1 AIN97088.1 - 0.0079 15.6 0.0 0.026 13.9 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.1 AIN97088.1 - 0.017 15.0 0.0 0.051 13.4 0.0 1.8 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.22 AIN97088.1 - 0.097 12.9 0.1 0.43 10.8 0.0 2.1 2 0 0 2 2 2 0 ABC transporter cobW PF02492.14 AIN97088.1 - 0.12 11.7 0.0 0.21 11.0 0.0 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain NACHT PF05729.7 AIN97088.1 - 0.15 11.7 0.0 0.38 10.4 0.0 1.7 1 0 0 1 1 1 0 NACHT domain RNA_helicase PF00910.17 AIN97088.1 - 0.22 11.7 0.0 0.65 10.1 0.0 1.8 1 0 0 1 1 1 0 RNA helicase ATP_bind_1 PF03029.12 AIN97088.1 - 0.28 10.6 0.0 0.5 9.8 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein Polyoma_lg_T_C PF06431.6 AIN97088.1 - 0.35 9.4 0.0 0.57 8.7 0.0 1.2 1 0 0 1 1 1 0 Polyomavirus large T antigen C-terminus Arch_ATPase PF01637.13 AIN97088.1 - 0.46 10.1 0.0 0.81 9.3 0.0 1.3 1 0 0 1 1 1 0 Archaeal ATPase RRM_1 PF00076.17 AIN97089.1 - 2.9e-13 49.2 0.4 5.4e-09 35.5 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 AIN97089.1 - 6.4e-12 45.2 0.5 5.4e-07 29.5 0.0 2.7 2 1 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 AIN97089.1 - 1e-10 41.2 1.0 1.8e-07 30.9 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) AsnC_trans_reg PF01037.16 AIN97089.1 - 0.063 12.9 0.0 3.3 7.4 0.0 2.5 2 0 0 2 2 2 0 AsnC family OmpH PF03938.9 AIN97091.1 - 0.97 9.3 21.5 2.8 7.8 0.4 3.6 2 2 1 3 3 3 0 Outer membrane protein (OmpH-like) Baculo_PEP_C PF04513.7 AIN97091.1 - 1.3 8.8 5.1 53 3.6 0.8 3.2 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF1664 PF07889.7 AIN97091.1 - 6.6 6.5 5.4 75 3.1 0.1 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) Metallophos PF00149.23 AIN97092.1 - 1.9e-05 24.1 0.0 3.8e-05 23.1 0.0 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 AIN97092.1 - 0.081 12.7 0.0 0.12 12.2 0.0 1.3 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain FliT PF05400.8 AIN97093.1 - 2.2 8.7 9.3 0.34 11.3 3.0 2.4 2 0 0 2 2 2 0 Flagellar protein FliT E1-E2_ATPase PF00122.15 AIN97094.1 - 1.2e-55 188.1 0.9 3.2e-55 186.6 0.6 1.8 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 AIN97094.1 - 5.6e-38 130.2 9.6 6.9e-38 129.9 5.3 2.0 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 AIN97094.1 - 1.8e-24 87.3 0.1 2.1e-23 83.8 0.1 2.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 AIN97094.1 - 6.2e-18 64.5 0.0 1.3e-17 63.5 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 AIN97094.1 - 3.1e-09 37.2 0.0 1.3e-08 35.2 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Peptidase_M50B PF13398.1 AIN97094.1 - 5.7e-05 22.5 3.8 7.6e-05 22.1 0.4 2.4 2 0 0 2 2 2 1 Peptidase M50B-like Hydrolase_3 PF08282.7 AIN97094.1 - 0.00015 21.4 0.8 0.0003 20.4 0.6 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase DUF3667 PF12412.3 AIN97094.1 - 0.13 11.5 0.0 0.26 10.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3667) ACBP PF00887.14 AIN97095.1 - 2.1e-33 113.8 2.1 9.8e-19 66.8 0.0 3.5 3 1 0 3 3 3 2 Acyl CoA binding protein ACBP PF00887.14 AIN97096.1 - 3.9e-30 103.3 0.1 4.6e-30 103.1 0.0 1.1 1 0 0 1 1 1 1 Acyl CoA binding protein ACBP PF00887.14 AIN97098.1 - 6.8e-29 99.3 0.1 7.6e-29 99.2 0.1 1.0 1 0 0 1 1 1 1 Acyl CoA binding protein Abhydrolase_6 PF12697.2 AIN97099.1 - 1e-08 35.3 2.7 2.2e-08 34.2 1.0 1.9 1 1 1 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 AIN97099.1 - 0.001 18.6 0.0 0.0013 18.3 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold PGAP1 PF07819.8 AIN97099.1 - 0.0058 16.2 0.0 0.011 15.3 0.0 1.4 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_5 PF12695.2 AIN97099.1 - 0.0072 16.0 0.0 0.011 15.5 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Ser_hydrolase PF06821.8 AIN97099.1 - 0.07 12.7 0.3 0.14 11.7 0.2 1.4 1 0 0 1 1 1 0 Serine hydrolase EF-hand_7 PF13499.1 AIN97100.1 - 1.1e-13 51.0 0.0 2.6e-10 40.2 0.0 3.1 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.1 AIN97100.1 - 5.2e-05 22.3 0.2 0.00023 20.3 0.0 2.1 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.1 AIN97100.1 - 5.6e-05 22.6 1.2 0.0027 17.4 0.0 3.5 4 0 0 4 4 4 1 EF-hand domain EF-hand_1 PF00036.27 AIN97100.1 - 0.00011 21.1 0.0 0.00076 18.6 0.0 2.5 2 0 0 2 2 2 1 EF hand EF-hand_8 PF13833.1 AIN97100.1 - 1.1 8.9 3.3 1.9 8.1 0.0 3.0 4 0 0 4 4 4 0 EF-hand domain pair GRAM PF02893.15 AIN97102.1 - 2.1e-11 43.1 0.4 8.2e-07 28.4 0.1 2.6 2 0 0 2 2 2 2 GRAM domain Pkinase PF00069.20 AIN97104.1 - 3.9e-67 226.1 0.0 5e-67 225.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain POLO_box PF00659.13 AIN97104.1 - 1.3e-43 146.7 0.0 9.1e-26 89.6 0.0 2.6 2 0 0 2 2 2 2 POLO box duplicated region Pkinase_Tyr PF07714.12 AIN97104.1 - 4.4e-38 130.8 0.0 6.1e-38 130.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 AIN97104.1 - 2.4e-10 39.8 0.0 1.4e-09 37.3 0.0 1.9 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 AIN97104.1 - 0.0051 16.5 4.3 0.033 13.9 0.0 3.3 2 1 1 3 3 3 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 AIN97104.1 - 0.09 11.5 0.1 0.15 10.8 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 DUF4520 PF15016.1 AIN97104.1 - 0.11 12.0 0.0 1.9 8.1 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4520) VID27 PF08553.5 AIN97105.1 - 1.5e-28 99.5 0.0 2.4e-28 98.8 0.0 1.2 1 0 0 1 1 1 1 VID27 cytoplasmic protein Pkinase PF00069.20 AIN97108.1 - 3.2e-22 78.9 0.0 2.1e-11 43.4 0.0 4.1 4 0 0 4 4 4 2 Protein kinase domain Pkinase_Tyr PF07714.12 AIN97108.1 - 0.0041 16.2 0.0 0.081 11.9 0.0 2.6 3 0 0 3 3 3 1 Protein tyrosine kinase Seadorna_VP7 PF07387.6 AIN97108.1 - 2.8 6.6 0.2 4.3 6.0 0.1 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Tudor-knot PF11717.3 AIN97109.1 - 0.14 11.9 0.1 0.26 11.0 0.0 1.5 1 0 0 1 1 1 0 RNA binding activity-knot of a chromodomain Methyltransf_16 PF10294.4 AIN97111.1 - 3.4e-20 72.2 0.0 2.1e-15 56.6 0.0 2.7 2 1 1 3 3 3 2 Putative methyltransferase Methyltransf_18 PF12847.2 AIN97111.1 - 0.00074 20.0 0.0 0.0014 19.1 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 AIN97111.1 - 0.0058 16.0 1.5 0.056 12.8 0.2 2.3 1 1 1 2 2 2 1 Methyltransferase small domain Myb_DNA-binding PF00249.26 AIN97112.1 - 3e-18 65.5 4.1 1.7e-10 40.8 0.2 2.6 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 AIN97112.1 - 6.4e-14 51.8 11.1 2.8e-09 36.9 0.4 2.9 2 0 0 2 2 2 2 Myb-like DNA-binding domain DUF3580 PF12117.3 AIN97112.1 - 0.013 15.4 1.2 1.7 8.6 0.1 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3580) Myb_DNA-bind_4 PF13837.1 AIN97112.1 - 0.031 14.3 4.0 0.54 10.4 0.1 3.6 3 0 0 3 3 3 0 Myb/SANT-like DNA-binding domain IMPDH PF00478.20 AIN97114.1 - 5.4e-134 446.5 3.2 6.3e-134 446.3 2.2 1.0 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain CBS PF00571.23 AIN97114.1 - 6.6e-12 45.0 0.0 3.8e-05 23.3 0.0 2.8 2 0 0 2 2 2 2 CBS domain FMN_dh PF01070.13 AIN97114.1 - 6.2e-08 31.8 7.9 1.4e-07 30.7 5.5 1.6 1 1 0 1 1 1 1 FMN-dependent dehydrogenase NMO PF03060.10 AIN97114.1 - 2.7e-06 26.7 10.9 0.058 12.5 8.4 2.7 2 1 1 3 3 3 2 Nitronate monooxygenase His_biosynth PF00977.16 AIN97114.1 - 0.00039 19.7 2.0 0.013 14.7 0.1 2.3 1 1 0 2 2 2 1 Histidine biosynthesis protein ParA PF10609.4 AIN97114.1 - 0.0011 18.7 0.3 2.9 7.8 0.0 3.3 3 0 0 3 3 3 2 ParA/MinD ATPase like Glu_synthase PF01645.12 AIN97114.1 - 0.0018 17.2 4.8 0.0032 16.4 3.3 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase DHO_dh PF01180.16 AIN97114.1 - 0.0019 17.2 4.6 0.02 13.8 0.5 2.3 2 0 0 2 2 2 1 Dihydroorotate dehydrogenase ThiG PF05690.9 AIN97114.1 - 0.0036 16.4 0.8 0.0036 16.4 0.6 2.4 2 0 0 2 2 2 1 Thiazole biosynthesis protein ThiG PcrB PF01884.12 AIN97114.1 - 0.0042 16.3 8.1 0.039 13.2 0.1 3.2 2 1 1 3 3 3 2 PcrB family Beta_elim_lyase PF01212.16 AIN97114.1 - 0.011 14.8 0.2 0.017 14.2 0.1 1.3 1 0 0 1 1 1 0 Beta-eliminating lyase NanE PF04131.9 AIN97114.1 - 0.085 11.8 3.5 1.7 7.6 0.1 2.8 2 1 0 2 2 2 0 Putative N-acetylmannosamine-6-phosphate epimerase Radical_SAM PF04055.16 AIN97114.1 - 0.13 12.4 0.0 2.1 8.4 0.0 2.4 1 1 1 2 2 2 0 Radical SAM superfamily Lysine_decarbox PF03641.9 AIN97115.1 - 7.2e-28 97.0 0.5 1.2e-27 96.3 0.3 1.3 1 0 0 1 1 1 1 Possible lysine decarboxylase ABM PF03992.11 AIN97115.1 - 4.6e-07 29.7 0.1 1e-06 28.6 0.1 1.5 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase Methyltransf_30 PF05430.6 AIN97115.1 - 0.092 12.4 0.0 0.18 11.4 0.0 1.5 1 0 0 1 1 1 0 S-adenosyl-L-methionine-dependent methyltransferase Kinesin PF00225.18 AIN97116.1 - 1.7e-102 342.5 0.0 1.7e-102 342.5 0.0 2.3 2 1 1 3 3 3 1 Kinesin motor domain COG5 PF10392.4 AIN97116.1 - 0.013 15.4 3.8 0.013 15.4 2.6 5.1 3 2 2 5 5 5 0 Golgi transport complex subunit 5 eIF-3c_N PF05470.7 AIN97117.1 - 0.034 12.2 0.6 0.049 11.7 0.4 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus G-patch PF01585.18 AIN97118.1 - 7.1e-12 44.9 0.2 1.5e-11 43.8 0.2 1.6 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.2 AIN97118.1 - 0.00022 21.0 0.5 0.00022 21.0 0.4 2.1 3 0 0 3 3 3 1 DExH-box splicing factor binding site S100PBPR PF15427.1 AIN97118.1 - 0.006 15.7 3.6 0.0074 15.4 2.5 1.1 1 0 0 1 1 1 1 S100P-binding protein BMP2K_C PF15282.1 AIN97118.1 - 0.03 14.4 3.9 0.036 14.2 2.7 1.2 1 0 0 1 1 1 0 BMP-2-inducible protein kinase C-terminus Nucleo_P87 PF07267.6 AIN97118.1 - 0.069 11.8 1.8 0.083 11.5 1.2 1.0 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Macoilin PF09726.4 AIN97118.1 - 1.2 7.2 7.0 1.4 7.1 4.8 1.0 1 0 0 1 1 1 0 Transmembrane protein DBR1 PF05011.8 AIN97120.1 - 6.3e-06 26.1 0.0 1.4e-05 24.9 0.0 1.6 1 0 0 1 1 1 1 Lariat debranching enzyme, C-terminal domain Metallophos_2 PF12850.2 AIN97120.1 - 0.0022 17.8 0.0 0.005 16.6 0.0 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.23 AIN97120.1 - 0.0023 17.3 0.3 0.011 15.1 0.2 2.0 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase ATP-synt_10 PF05176.9 AIN97121.1 - 0.0012 18.1 0.0 0.0032 16.7 0.0 1.7 1 0 0 1 1 1 1 ATP10 protein DUF1935 PF09149.5 AIN97124.1 - 8.7e-34 115.6 0.0 1.8e-33 114.6 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1935) META PF03724.11 AIN97124.1 - 1.8e-21 75.8 0.3 3.5e-09 36.4 0.0 3.5 3 0 0 3 3 3 3 META domain DUF4448 PF14610.1 AIN97125.1 - 0.14 11.6 0.0 0.28 10.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) META PF03724.11 AIN97126.1 - 1.7e-10 40.6 0.0 2.1e-10 40.3 0.0 1.1 1 0 0 1 1 1 1 META domain LRR_6 PF13516.1 AIN97127.1 - 9.3e-11 40.6 1.2 0.79 9.9 0.0 6.9 7 0 0 7 7 7 2 Leucine Rich repeat LRR_4 PF12799.2 AIN97127.1 - 2.4e-10 39.7 0.0 0.052 13.1 0.0 4.0 4 0 0 4 4 4 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 AIN97127.1 - 1.3e-06 27.5 0.5 10 6.5 0.0 5.9 5 1 0 5 5 5 2 Leucine Rich Repeat LRR_7 PF13504.1 AIN97127.1 - 0.00077 19.2 6.4 25 5.6 0.0 6.4 7 0 0 7 7 7 0 Leucine rich repeat LRR_8 PF13855.1 AIN97127.1 - 0.006 16.3 2.4 10 5.9 0.0 4.0 2 2 1 3 3 3 2 Leucine rich repeat DUF3729 PF12526.3 AIN97127.1 - 1.1 10.5 7.2 0.45 11.8 2.8 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3729) Acyltransferase PF01553.16 AIN97128.1 - 1.8e-14 53.3 0.0 2.9e-14 52.6 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase Sec63 PF02889.11 AIN97129.1 - 2.8e-59 200.8 0.0 4.5e-55 187.0 0.0 2.5 2 1 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.24 AIN97129.1 - 2e-36 124.9 0.1 2.4e-27 95.5 0.3 2.7 2 0 0 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.26 AIN97129.1 - 2.8e-08 33.5 0.0 7.1e-08 32.2 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 AIN97129.1 - 1.5e-07 31.4 0.0 1.6e-06 28.0 0.0 2.3 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit IstB_IS21 PF01695.12 AIN97129.1 - 0.018 14.4 0.1 9.5 5.5 0.0 2.9 3 0 0 3 3 3 0 IstB-like ATP binding protein UvrD-helicase PF00580.16 AIN97129.1 - 0.44 9.7 0.0 1.2 8.3 0.0 1.7 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain FH2 PF02181.18 AIN97130.1 - 1.3e-48 165.8 0.0 1.9e-48 165.2 0.0 1.2 1 0 0 1 1 1 1 Formin Homology 2 Domain Med9 PF07544.8 AIN97130.1 - 0.00029 20.5 0.1 0.00096 18.8 0.1 1.9 1 0 0 1 1 1 1 RNA polymerase II transcription mediator complex subunit 9 CUE PF02845.11 AIN97130.1 - 0.0021 17.5 0.0 0.012 15.1 0.0 2.2 2 0 0 2 2 2 1 CUE domain PCIF1_WW PF12237.3 AIN97131.1 - 2e-34 118.3 0.2 1e-32 112.8 0.1 3.0 2 1 0 2 2 2 1 Phosphorylated CTD interacting factor 1 WW domain PDEase_I PF00233.14 AIN97132.1 - 5.3e-11 42.7 0.4 9.7e-07 28.7 0.1 2.6 2 1 0 2 2 2 2 3'5'-cyclic nucleotide phosphodiesterase Mak10 PF04112.8 AIN97133.1 - 6.1e-07 28.8 0.0 2.3e-06 26.9 0.0 2.0 1 1 0 1 1 1 1 Mak10 subunit, NatC N(alpha)-terminal acetyltransferase PI3_PI4_kinase PF00454.22 AIN97134.1 - 0.0015 18.0 0.0 0.0028 17.1 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase IL8 PF00048.15 AIN97134.1 - 1.4 8.9 0.0 19 5.3 0.0 2.4 2 0 0 2 2 2 0 Small cytokines (intecrine/chemokine), interleukin-8 like Abhydrolase_6 PF12697.2 AIN97136.1 - 8.9e-29 100.9 0.1 1.2e-28 100.5 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 AIN97136.1 - 1e-19 71.0 0.0 3.1e-19 69.4 0.0 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 AIN97136.1 - 5.9e-16 58.5 0.0 1.1e-15 57.7 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 AIN97136.1 - 3.5e-05 23.1 0.1 0.033 13.3 0.0 2.6 3 0 0 3 3 3 2 Prolyl oligopeptidase family FSH1 PF03959.8 AIN97136.1 - 0.00011 21.7 0.1 0.00028 20.3 0.0 1.7 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_2 PF02230.11 AIN97136.1 - 0.00011 21.7 0.0 0.0074 15.7 0.0 2.3 2 0 0 2 2 2 1 Phospholipase/Carboxylesterase Esterase PF00756.15 AIN97136.1 - 0.00013 21.5 0.1 0.00022 20.7 0.0 1.4 1 1 0 1 1 1 1 Putative esterase Abhydrolase_4 PF08386.5 AIN97136.1 - 0.00026 20.8 0.0 0.00059 19.6 0.0 1.5 1 0 0 1 1 1 1 TAP-like protein PGAP1 PF07819.8 AIN97136.1 - 0.00038 20.1 0.4 0.00097 18.7 0.2 1.7 2 0 0 2 2 2 1 PGAP1-like protein Hydrolase_4 PF12146.3 AIN97136.1 - 0.0018 18.0 0.0 0.0058 16.4 0.0 1.8 2 0 0 2 2 2 1 Putative lysophospholipase Esterase_phd PF10503.4 AIN97136.1 - 0.002 17.4 0.0 1.3 8.2 0.0 2.3 1 1 0 2 2 2 2 Esterase PHB depolymerase Ndr PF03096.9 AIN97136.1 - 0.0032 15.9 0.0 0.0044 15.5 0.0 1.3 1 0 0 1 1 1 1 Ndr family DLH PF01738.13 AIN97136.1 - 0.014 14.6 0.0 0.97 8.6 0.0 2.6 2 2 0 2 2 2 0 Dienelactone hydrolase family DUF2048 PF09752.4 AIN97136.1 - 0.074 11.9 0.0 0.087 11.6 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2048) LIP PF03583.9 AIN97136.1 - 0.09 11.9 0.0 0.69 9.0 0.0 2.1 2 0 0 2 2 2 0 Secretory lipase Abhydrolase_3 PF07859.8 AIN97136.1 - 0.11 12.0 0.1 0.26 10.8 0.0 1.7 1 1 0 1 1 1 0 alpha/beta hydrolase fold GlcNAc PF11397.3 AIN97137.1 - 1.1e-136 455.5 0.0 1.3e-136 455.2 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase (GlcNAc) DUF2721 PF11026.3 AIN97137.1 - 0.021 14.4 0.2 0.039 13.6 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2721) DUF2452 PF10504.4 AIN97137.1 - 0.22 10.7 0.0 0.39 9.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2452) Abhydrolase_6 PF12697.2 AIN97139.1 - 1.7e-23 83.7 1.4 9e-23 81.3 1.0 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 AIN97139.1 - 3.6e-18 65.9 0.4 9.2e-18 64.6 0.3 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 AIN97139.1 - 2.3e-11 43.6 0.0 1.1e-10 41.3 0.0 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_4 PF08386.5 AIN97139.1 - 5.2e-06 26.2 0.0 1e-05 25.3 0.0 1.6 1 0 0 1 1 1 1 TAP-like protein DUF2048 PF09752.4 AIN97139.1 - 0.0025 16.7 0.1 0.0081 15.0 0.1 1.7 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2048) Esterase_phd PF10503.4 AIN97139.1 - 0.017 14.4 0.1 0.28 10.3 0.0 2.2 2 0 0 2 2 2 0 Esterase PHB depolymerase Ser_hydrolase PF06821.8 AIN97139.1 - 0.027 14.0 0.1 0.07 12.7 0.0 1.6 2 0 0 2 2 2 0 Serine hydrolase Peptidase_S9 PF00326.16 AIN97139.1 - 0.038 13.2 0.0 3.7 6.7 0.0 2.2 2 0 0 2 2 2 0 Prolyl oligopeptidase family Ndr PF03096.9 AIN97139.1 - 0.05 12.0 0.0 0.074 11.5 0.0 1.3 1 0 0 1 1 1 0 Ndr family Esterase PF00756.15 AIN97139.1 - 0.075 12.4 0.0 0.14 11.5 0.0 1.4 1 0 0 1 1 1 0 Putative esterase Abhydrolase_3 PF07859.8 AIN97139.1 - 0.11 12.1 0.0 2.6 7.5 0.0 2.5 3 0 0 3 3 3 0 alpha/beta hydrolase fold PGAP1 PF07819.8 AIN97139.1 - 0.14 11.7 0.2 0.22 11.0 0.1 1.3 1 0 0 1 1 1 0 PGAP1-like protein Abhydrolase_6 PF12697.2 AIN97140.1 - 3.1e-30 105.7 0.9 4.4e-30 105.2 0.6 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 AIN97140.1 - 1.9e-19 70.1 0.0 4.6e-19 68.8 0.0 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 AIN97140.1 - 4.4e-15 55.6 0.0 5e-14 52.2 0.0 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.15 AIN97140.1 - 4.9e-05 22.8 0.0 0.00022 20.7 0.0 1.9 2 0 0 2 2 2 1 Putative esterase Abhydrolase_2 PF02230.11 AIN97140.1 - 0.00029 20.3 0.0 0.03 13.7 0.0 2.2 2 0 0 2 2 2 1 Phospholipase/Carboxylesterase Abhydrolase_4 PF08386.5 AIN97140.1 - 0.0003 20.6 0.0 0.00058 19.7 0.0 1.5 1 0 0 1 1 1 1 TAP-like protein Esterase_phd PF10503.4 AIN97140.1 - 0.0015 17.8 0.2 0.074 12.2 0.0 2.2 2 0 0 2 2 2 1 Esterase PHB depolymerase Ndr PF03096.9 AIN97140.1 - 0.0047 15.4 0.0 0.012 14.1 0.0 1.6 2 0 0 2 2 2 1 Ndr family Hydrolase_4 PF12146.3 AIN97140.1 - 0.007 16.1 0.0 0.023 14.5 0.0 1.9 2 0 0 2 2 2 1 Putative lysophospholipase Thioesterase PF00975.15 AIN97140.1 - 0.015 15.5 0.1 0.033 14.4 0.0 1.5 1 0 0 1 1 1 0 Thioesterase domain FIST PF08495.5 AIN97140.1 - 0.03 13.4 0.1 0.063 12.4 0.1 1.5 1 0 0 1 1 1 0 FIST N domain DLH PF01738.13 AIN97140.1 - 0.038 13.2 0.0 0.77 9.0 0.0 2.1 2 0 0 2 2 2 0 Dienelactone hydrolase family DUF2048 PF09752.4 AIN97140.1 - 0.09 11.6 0.5 0.14 11.0 0.3 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2048) Ser_hydrolase PF06821.8 AIN97140.1 - 0.13 11.8 0.3 0.27 10.8 0.0 1.6 2 0 0 2 2 2 0 Serine hydrolase Abhydrolase_6 PF12697.2 AIN97141.1 - 2.6e-24 86.3 2.0 2.6e-24 86.3 1.4 2.1 3 1 0 3 3 3 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 AIN97141.1 - 5.7e-17 62.0 0.0 1.3e-16 60.8 0.0 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 AIN97141.1 - 2e-13 50.3 0.0 5.5e-13 48.8 0.0 1.8 1 0 0 1 1 1 1 Alpha/beta hydrolase family Thioesterase PF00975.15 AIN97141.1 - 0.00099 19.3 0.0 0.0019 18.4 0.0 1.4 1 0 0 1 1 1 1 Thioesterase domain Abhydrolase_4 PF08386.5 AIN97141.1 - 0.002 17.9 0.1 0.0093 15.8 0.0 2.0 2 0 0 2 2 2 1 TAP-like protein Ndr PF03096.9 AIN97141.1 - 0.14 10.5 0.0 0.27 9.6 0.0 1.3 1 0 0 1 1 1 0 Ndr family PLAC8 PF04749.12 AIN97142.1 - 1.4 9.4 20.0 1.2 9.6 11.1 2.5 2 1 0 2 2 2 0 PLAC8 family UCH PF00443.24 AIN97144.1 - 1.7e-20 73.2 0.0 3.2e-20 72.3 0.0 1.5 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 AIN97144.1 - 1.7e-07 31.0 0.0 6.9e-07 28.9 0.0 2.0 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase Steroid_dh PF02544.11 AIN97145.1 - 2.1e-24 85.9 2.7 1.1e-09 38.2 0.0 4.4 4 0 0 4 4 4 4 3-oxo-5-alpha-steroid 4-dehydrogenase Kinesin PF00225.18 AIN97146.1 - 1e-85 287.4 0.0 1.6e-85 286.8 0.0 1.3 1 0 0 1 1 1 1 Kinesin motor domain Calpain_III PF01067.17 AIN97146.1 - 3.5e-25 88.3 0.4 1.6e-20 73.2 0.0 2.8 3 0 0 3 3 3 2 Calpain large subunit, domain III Arm PF00514.18 AIN97146.1 - 3.2e-06 26.7 9.1 0.33 10.8 0.1 6.2 7 0 0 7 7 7 3 Armadillo/beta-catenin-like repeat Nol1_Nop2_Fmu PF01189.12 AIN97148.1 - 4.3e-25 88.6 0.0 6.5e-15 55.2 0.0 2.8 3 0 0 3 3 3 2 NOL1/NOP2/sun family WW PF00397.21 AIN97149.1 - 6e-08 32.4 1.4 6.2e-08 32.3 0.1 1.8 2 0 0 2 2 2 1 WW domain ATP_Ca_trans_C PF12424.3 AIN97149.1 - 0.63 10.4 6.1 0.29 11.5 0.2 3.4 2 1 1 3 3 3 0 Plasma membrane calcium transporter ATPase C terminal XRN_N PF03159.13 AIN97150.1 - 1.9e-63 214.0 0.0 8.9e-31 107.0 0.0 2.2 2 0 0 2 2 2 2 XRN 5'-3' exonuclease N-terminus zf-RanBP PF00641.13 AIN97150.1 - 0.0001 21.3 6.4 0.00027 19.9 4.5 1.7 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others UDPGP PF01704.13 AIN97151.1 - 3.6e-08 32.3 0.0 1.2e-07 30.6 0.0 1.6 2 0 0 2 2 2 1 UTP--glucose-1-phosphate uridylyltransferase DUF4375 PF14300.1 AIN97151.1 - 0.0038 17.2 0.0 0.0071 16.3 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4375) FlaC_arch PF05377.6 AIN97153.1 - 0.29 11.0 0.3 1.5 8.7 0.0 2.2 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) DUF1192 PF06698.6 AIN97153.1 - 0.44 10.3 16.7 0.44 10.3 1.9 3.8 3 0 0 3 3 3 0 Protein of unknown function (DUF1192) DUF1843 PF08898.5 AIN97153.1 - 5.6 7.0 20.5 2.5 8.2 0.0 5.2 4 1 1 5 5 5 0 Domain of unknown function (DUF1843) ATG16 PF08614.6 AIN97155.1 - 4.9e-05 23.2 5.4 0.011 15.6 0.9 3.0 1 1 1 2 2 2 2 Autophagy protein 16 (ATG16) Cast PF10174.4 AIN97155.1 - 0.00014 20.0 0.5 0.065 11.2 0.0 2.0 1 1 0 2 2 2 2 RIM-binding protein of the cytomatrix active zone DUF904 PF06005.7 AIN97155.1 - 0.082 13.2 4.4 0.61 10.4 0.6 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF904) ADIP PF11559.3 AIN97155.1 - 0.12 12.3 4.4 0.19 11.6 0.2 2.4 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding SlyX PF04102.7 AIN97155.1 - 0.17 12.2 2.6 3.1 8.2 0.0 2.6 2 0 0 2 2 2 0 SlyX CENP-Q PF13094.1 AIN97155.1 - 1.7 8.6 9.3 0.6 10.1 1.0 2.3 1 1 1 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit DivIC PF04977.10 AIN97155.1 - 6.1 6.4 5.7 1.2 8.7 0.4 2.2 2 0 0 2 2 2 0 Septum formation initiator Motile_Sperm PF00635.21 AIN97156.1 - 1.3e-10 40.8 0.1 2.5e-10 39.9 0.0 1.5 1 0 0 1 1 1 1 MSP (Major sperm protein) domain TPR_11 PF13414.1 AIN97158.1 - 3.4e-13 49.0 3.2 2.2e-07 30.4 0.0 5.1 3 1 2 5 5 5 3 TPR repeat TPR_2 PF07719.12 AIN97158.1 - 4.9e-12 44.8 6.3 0.00058 19.5 0.0 6.2 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_17 PF13431.1 AIN97158.1 - 4.1e-09 35.9 0.0 0.033 14.3 0.0 4.7 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.23 AIN97158.1 - 9.6e-07 28.1 0.3 0.055 13.1 0.0 3.9 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.1 AIN97158.1 - 1.8e-05 24.1 0.1 2.4 8.1 0.0 5.2 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_14 PF13428.1 AIN97158.1 - 0.00021 21.6 37.3 0.16 12.6 0.0 9.8 10 2 2 12 12 10 4 Tetratricopeptide repeat TPR_7 PF13176.1 AIN97158.1 - 0.00085 18.9 1.3 44 4.2 0.3 5.2 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_19 PF14559.1 AIN97158.1 - 0.0054 17.0 0.1 18 5.7 0.0 4.7 3 2 2 5 5 5 0 Tetratricopeptide repeat Clathrin PF00637.15 AIN97158.1 - 0.023 14.3 0.3 0.081 12.5 0.1 2.0 2 0 0 2 2 2 0 Region in Clathrin and VPS TPR_16 PF13432.1 AIN97158.1 - 0.11 13.2 21.1 1.7 9.4 0.2 5.9 7 1 0 8 8 7 0 Tetratricopeptide repeat TPR_6 PF13174.1 AIN97158.1 - 2.4 8.8 4.8 93 3.8 0.0 5.4 5 1 0 5 5 5 0 Tetratricopeptide repeat GNAT_acetyltr_2 PF13718.1 AIN97159.1 - 1.9e-68 229.7 0.0 3.9e-68 228.6 0.0 1.6 1 0 0 1 1 1 1 GNAT acetyltransferase 2 Helicase_RecD PF05127.9 AIN97159.1 - 3.7e-60 202.5 0.0 8.9e-60 201.3 0.0 1.7 1 0 0 1 1 1 1 Helicase DUF1726 PF08351.6 AIN97159.1 - 4.5e-35 119.1 0.0 1.6e-34 117.4 0.0 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1726) tRNA_bind_2 PF13725.1 AIN97159.1 - 7.2e-17 61.3 0.0 2.4e-16 59.6 0.0 2.0 1 0 0 1 1 1 1 Possible tRNA binding domain Oscp1 PF10188.4 AIN97160.1 - 1.4e-60 204.0 0.0 1.8e-60 203.7 0.0 1.1 1 0 0 1 1 1 1 Organic solute transport protein 1 eIF2A PF08662.6 AIN97163.1 - 1.5e-13 50.9 0.0 4e-13 49.5 0.0 1.8 1 0 0 1 1 1 1 Eukaryotic translation initiation factor eIF2A DUF2252 PF10009.4 AIN97163.1 - 0.33 9.8 8.5 0.5 9.2 5.9 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2252) PhnH PF05845.7 AIN97164.1 - 0.014 14.8 0.3 0.88 9.0 0.0 2.2 2 0 0 2 2 2 0 Bacterial phosphonate metabolism protein (PhnH) Methyltransf_32 PF13679.1 AIN97165.1 - 3.9e-11 42.8 3.7 5.7e-06 26.0 0.5 2.7 2 1 0 2 2 2 2 Methyltransferase domain CTP_transf_2 PF01467.21 AIN97168.1 - 1.1e-18 67.7 0.0 1.6e-18 67.2 0.0 1.3 1 1 0 1 1 1 1 Cytidylyltransferase Cyt-b5 PF00173.23 AIN97169.1 - 4.6e-17 61.5 0.0 7.7e-17 60.8 0.0 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain ALO PF04030.9 AIN97170.1 - 3e-71 240.0 3.5 2.7e-67 227.0 0.5 2.2 2 0 0 2 2 2 2 D-arabinono-1,4-lactone oxidase FAD_binding_4 PF01565.18 AIN97170.1 - 5.7e-22 77.6 0.7 1e-21 76.8 0.1 1.7 2 0 0 2 2 2 1 FAD binding domain SDA1 PF05285.7 AIN97171.1 - 1.4e-95 320.2 39.4 1.4e-95 320.2 27.3 2.7 2 1 0 2 2 2 1 SDA1 NUC130_3NT PF08158.7 AIN97171.1 - 8.5e-16 57.9 0.1 2.2e-15 56.6 0.0 1.8 1 0 0 1 1 1 1 NUC130/3NT domain IQ PF00612.22 AIN97173.1 - 8.9e-11 40.4 39.5 0.008 15.7 0.6 7.0 6 0 0 6 6 6 5 IQ calmodulin-binding motif Inositol_P PF00459.20 AIN97174.1 - 2e-51 174.9 0.4 2.5e-51 174.5 0.3 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family Peptidase_C65 PF10275.4 AIN97175.1 - 2e-55 187.8 0.1 2.2e-55 187.6 0.1 1.0 1 0 0 1 1 1 1 Peptidase C65 Otubain OTU PF02338.14 AIN97175.1 - 2.7e-05 24.7 0.8 0.017 15.6 0.4 2.6 2 1 0 2 2 2 1 OTU-like cysteine protease FlaC_arch PF05377.6 AIN97175.1 - 0.13 12.2 0.2 6.4 6.7 0.0 2.4 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) zf-ZPR1 PF03367.8 AIN97176.1 - 5.4e-105 347.4 0.3 1.2e-53 180.6 0.1 2.1 2 0 0 2 2 2 2 ZPR1 zinc-finger domain HypA PF01155.14 AIN97176.1 - 0.016 14.8 4.1 2.1 8.0 0.1 2.5 2 0 0 2 2 2 0 Hydrogenase expression/synthesis hypA family Zn-ribbon_8 PF09723.5 AIN97176.1 - 0.19 11.6 9.2 30 4.6 0.1 4.3 4 0 0 4 4 4 0 Zinc ribbon domain zf-H2C2_2 PF13465.1 AIN97176.1 - 2.9 8.3 13.7 10 6.6 0.3 4.3 4 0 0 4 4 4 0 Zinc-finger double domain DltD_M PF04918.7 AIN97177.1 - 0.42 10.7 6.8 0.7 10.0 4.7 1.5 1 0 0 1 1 1 0 DltD central region DUF4200 PF13863.1 AIN97177.1 - 0.7 9.8 34.3 0.43 10.5 4.0 3.2 1 1 2 3 3 3 0 Domain of unknown function (DUF4200) Spc7 PF08317.6 AIN97177.1 - 2.9 6.4 24.5 1.8 7.1 9.5 2.1 1 1 1 2 2 2 0 Spc7 kinetochore protein MFS_1 PF07690.11 AIN97178.1 - 1.5e-19 69.9 40.3 1.5e-19 69.9 27.9 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily Ion_trans PF00520.26 AIN97179.1 - 2.6e-08 33.3 6.4 5.5e-08 32.3 4.4 1.5 1 0 0 1 1 1 1 Ion transport protein RabGAP-TBC PF00566.13 AIN97180.1 - 5.2e-18 65.3 0.1 8.3e-18 64.6 0.1 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Ferrochelatase PF00762.14 AIN97181.1 - 6.8e-65 219.1 0.0 1.1e-49 169.1 0.0 2.1 2 0 0 2 2 2 2 Ferrochelatase Pex14_N PF04695.8 AIN97182.1 - 3.5 7.6 9.7 1.3 9.0 0.6 2.3 1 1 1 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region PPR_2 PF13041.1 AIN97183.1 - 8.5e-52 172.9 4.9 5.8e-09 35.7 0.0 12.9 10 3 5 15 15 15 9 PPR repeat family PPR PF01535.15 AIN97183.1 - 1.9e-44 146.5 13.0 0.0021 17.8 0.0 17.1 18 0 0 18 18 18 10 PPR repeat PPR_3 PF13812.1 AIN97183.1 - 9.1e-34 112.8 11.0 0.12 12.7 0.0 17.5 18 1 0 18 18 18 10 Pentatricopeptide repeat domain PPR_1 PF12854.2 AIN97183.1 - 1.4e-14 53.2 16.9 0.064 12.7 0.0 11.5 14 0 0 14 14 14 5 PPR repeat TPR_14 PF13428.1 AIN97183.1 - 7.3e-07 29.2 3.4 4 8.3 0.0 6.8 4 1 2 6 6 6 2 Tetratricopeptide repeat TPR_16 PF13432.1 AIN97183.1 - 1.9e-05 25.1 1.1 0.7 10.6 0.2 4.3 3 0 0 3 3 3 1 Tetratricopeptide repeat SPOB_a PF14689.1 AIN97183.1 - 0.0017 17.8 1.4 7.5 6.1 0.0 5.4 4 1 1 5 5 5 1 Sensor_kinase_SpoOB-type, alpha-helical domain TPR_12 PF13424.1 AIN97183.1 - 0.0023 17.8 5.6 1.3 9.0 0.9 4.7 3 1 2 5 5 5 2 Tetratricopeptide repeat ECSIT PF06239.6 AIN97183.1 - 0.003 16.4 0.0 5.2 5.8 0.0 3.9 3 1 1 4 4 4 2 Evolutionarily conserved signalling intermediate in Toll pathway GHMP_kinases_N PF00288.21 AIN97184.1 - 5.4e-06 26.3 3.5 1.7e-05 24.8 2.4 1.9 1 0 0 1 1 1 1 GHMP kinases N terminal domain DUF1819 PF08849.6 AIN97184.1 - 0.092 12.1 0.0 0.14 11.5 0.0 1.2 1 0 0 1 1 1 0 Putative inner membrane protein (DUF1819) GHMP_kinases_C PF08544.8 AIN97184.1 - 0.1 12.8 0.0 0.32 11.2 0.0 1.9 1 0 0 1 1 1 0 GHMP kinases C terminal RRM_1 PF00076.17 AIN97185.1 - 0.00011 21.7 0.0 0.00018 21.0 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 AIN97185.1 - 0.00021 21.0 0.0 0.0004 20.1 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 AIN97185.1 - 0.028 14.3 0.0 0.049 13.6 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) DUF1173 PF06666.6 AIN97185.1 - 0.077 11.8 0.0 0.12 11.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1173) zf-C2HC_2 PF13913.1 AIN97188.1 - 1.2e-37 126.8 61.7 1.3e-09 37.4 1.2 8.4 9 0 0 9 9 9 6 zinc-finger of a C2HC-type DZR PF12773.2 AIN97188.1 - 1.6e-13 50.2 67.6 4.1e-10 39.3 9.1 8.6 7 2 1 8 8 8 3 Double zinc ribbon zf-ribbon_3 PF13248.1 AIN97188.1 - 9.4e-10 37.3 54.5 0.0001 21.4 1.1 9.8 8 1 3 11 11 11 6 zinc-ribbon domain zinc_ribbon_2 PF13240.1 AIN97188.1 - 1.3e-07 30.8 54.4 0.0062 15.9 0.6 9.1 8 1 1 9 9 9 5 zinc-ribbon domain NOB1_Zn_bind PF08772.6 AIN97188.1 - 0.87 9.4 37.1 0.035 13.9 1.4 6.0 4 1 1 5 5 5 0 Nin one binding (NOB1) Zn-ribbon like 3Beta_HSD PF01073.14 AIN97189.1 - 1e-10 40.8 0.0 1.5e-10 40.3 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 AIN97189.1 - 4.7e-07 29.9 0.0 9e-07 29.0 0.0 1.5 1 1 0 1 1 1 1 NADH(P)-binding RmlD_sub_bind PF04321.12 AIN97189.1 - 0.00021 20.2 0.1 0.13 11.1 0.0 3.2 3 1 0 3 3 3 2 RmlD substrate binding domain NmrA PF05368.8 AIN97189.1 - 0.0017 17.6 0.0 0.0027 16.9 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family Semialdhyde_dh PF01118.19 AIN97189.1 - 0.0023 18.2 0.0 0.0055 16.9 0.0 1.7 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain adh_short PF00106.20 AIN97189.1 - 0.009 15.9 0.0 0.021 14.7 0.0 1.6 1 0 0 1 1 1 1 short chain dehydrogenase Epimerase PF01370.16 AIN97189.1 - 0.058 12.8 0.2 0.14 11.5 0.0 1.7 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family DapB_N PF01113.15 AIN97189.1 - 0.11 12.3 0.0 0.19 11.6 0.0 1.4 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Glyco_hydro_31 PF01055.21 AIN97190.1 - 1.2e-144 482.4 5.5 1.4e-144 482.1 3.8 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.1 AIN97190.1 - 1.9e-16 59.6 0.2 9.5e-16 57.4 0.1 2.4 2 0 0 2 2 2 1 Galactose mutarotase-like DUF726 PF05277.7 AIN97192.1 - 4.2e-57 193.5 21.2 2.2e-54 184.6 0.0 3.2 2 1 0 2 2 2 1 Protein of unknown function (DUF726) Abhydrolase_6 PF12697.2 AIN97192.1 - 0.00073 19.4 0.0 0.0023 17.8 0.0 1.9 1 0 0 1 1 1 1 Alpha/beta hydrolase family VirJ PF06057.6 AIN97192.1 - 0.0029 17.4 0.0 2.7 7.7 0.0 2.4 2 0 0 2 2 2 2 Bacterial virulence protein (VirJ) Abhydrolase_5 PF12695.2 AIN97192.1 - 0.0074 16.0 2.1 0.0082 15.9 0.0 2.2 3 0 0 3 3 3 1 Alpha/beta hydrolase family DUF2352 PF09817.4 AIN97193.1 - 0.021 13.0 0.0 0.023 12.8 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2352) CsgE PF10627.4 AIN97193.1 - 0.15 11.8 0.6 0.35 10.6 0.0 1.9 2 1 0 2 2 2 0 Curli assembly protein CsgE DUF21 PF01595.15 AIN97194.1 - 5.5e-25 87.7 0.3 9.8e-25 86.9 0.2 1.4 1 0 0 1 1 1 1 Domain of unknown function DUF21 CBS PF00571.23 AIN97194.1 - 1e-08 34.7 3.9 0.00023 20.8 0.0 3.9 4 0 0 4 4 4 3 CBS domain cNMP_binding PF00027.24 AIN97194.1 - 8.4e-05 22.3 0.0 0.0002 21.0 0.0 1.6 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain DUF21 PF01595.15 AIN97195.1 - 6.3e-36 123.3 0.1 1.1e-35 122.5 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function DUF21 cNMP_binding PF00027.24 AIN97195.1 - 3.6e-05 23.4 0.0 0.0001 22.0 0.0 1.7 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain CBS PF00571.23 AIN97195.1 - 0.0032 17.2 4.5 0.97 9.2 0.4 4.1 2 1 1 3 3 3 2 CBS domain Metallophos PF00149.23 AIN97196.1 - 4.5e-38 130.6 0.2 6.6e-38 130.1 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase PPP5 PF08321.7 AIN97196.1 - 2.4e-22 78.7 0.2 5.2e-22 77.6 0.2 1.6 1 0 0 1 1 1 1 PPP5 TPR repeat region TPR_11 PF13414.1 AIN97196.1 - 4.4e-19 67.9 5.0 3.5e-14 52.1 0.4 2.4 1 1 1 2 2 2 2 TPR repeat TPR_1 PF00515.23 AIN97196.1 - 2.8e-15 55.1 1.1 3.9e-05 23.0 0.0 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.12 AIN97196.1 - 6.7e-13 47.4 2.9 0.0015 18.3 0.0 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_16 PF13432.1 AIN97196.1 - 2.7e-05 24.7 5.0 7.8e-05 23.2 2.4 2.4 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_17 PF13431.1 AIN97196.1 - 0.00011 22.0 0.3 0.00092 19.2 0.0 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.1 AIN97196.1 - 0.00071 19.1 0.6 11 6.0 0.0 3.6 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.1 AIN97196.1 - 0.0014 19.0 2.6 0.16 12.7 0.1 3.2 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.1 AIN97196.1 - 0.002 18.0 1.4 0.022 14.6 0.3 2.3 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.1 AIN97196.1 - 0.003 17.8 1.3 0.0064 16.8 0.9 1.6 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_9 PF13371.1 AIN97196.1 - 0.0037 17.0 0.5 0.1 12.4 0.1 2.3 1 1 1 2 2 2 1 Tetratricopeptide repeat Paf67 PF10255.4 AIN97196.1 - 0.11 11.3 0.0 0.17 10.7 0.0 1.2 1 0 0 1 1 1 0 RNA polymerase I-associated factor PAF67 NYD-SP12_N PF15015.1 AIN97196.1 - 0.14 10.3 0.0 0.2 9.8 0.0 1.1 1 0 0 1 1 1 0 Spermatogenesis-associated, N-terminal Lipase_3 PF01764.20 AIN97197.1 - 5.4e-13 48.7 0.0 9.8e-13 47.9 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.2 AIN97197.1 - 0.00022 21.1 0.0 0.00082 19.3 0.0 1.9 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 AIN97197.1 - 0.004 16.8 0.0 0.0083 15.8 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 AIN97197.1 - 0.17 11.4 0.1 0.33 10.5 0.1 1.4 1 0 0 1 1 1 0 PGAP1-like protein RRM_1 PF00076.17 AIN97198.1 - 6.3e-29 99.4 0.0 1.9e-16 59.4 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 AIN97198.1 - 2.1e-22 78.8 0.0 3.5e-10 39.7 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 AIN97198.1 - 2.8e-12 46.2 0.0 4.1e-08 32.9 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 AIN97198.1 - 0.0035 17.0 0.0 0.38 10.5 0.0 2.5 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif Limkain-b1 PF11608.3 AIN97198.1 - 0.16 11.7 0.2 1.2 8.8 0.0 2.5 2 1 1 3 3 3 0 Limkain b1 RRM_1 PF00076.17 AIN97199.1 - 7.6e-30 102.3 0.0 5.3e-17 61.2 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 AIN97199.1 - 4e-20 71.5 0.1 1.9e-10 40.5 0.1 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 AIN97199.1 - 1.5e-11 43.9 0.0 7.2e-08 32.1 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Amino_oxidase PF01593.19 AIN97200.1 - 6.3e-11 41.9 0.0 2e-07 30.4 0.0 2.8 3 0 0 3 3 3 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 AIN97200.1 - 7e-10 38.7 1.3 1.7e-09 37.5 0.1 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 AIN97200.1 - 1e-05 25.7 0.0 0.0001 22.4 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 AIN97200.1 - 0.00025 20.8 0.2 0.003 17.3 0.0 2.7 3 0 0 3 3 3 1 FAD-NAD(P)-binding DAO PF01266.19 AIN97200.1 - 0.0075 15.2 0.1 0.017 14.0 0.1 1.6 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 AIN97200.1 - 0.041 13.7 0.1 0.1 12.4 0.0 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase HhH-GPD PF00730.20 AIN97200.1 - 0.053 13.8 0.0 0.097 12.9 0.0 1.4 1 0 0 1 1 1 0 HhH-GPD superfamily base excision DNA repair protein Thi4 PF01946.12 AIN97200.1 - 0.062 12.3 0.0 0.11 11.5 0.0 1.4 1 0 0 1 1 1 0 Thi4 family GLF PF03275.8 AIN97200.1 - 0.089 12.2 0.0 0.43 10.0 0.0 2.2 3 0 0 3 3 3 0 UDP-galactopyranose mutase HI0933_like PF03486.9 AIN97200.1 - 0.16 10.3 0.1 0.26 9.7 0.0 1.2 1 0 0 1 1 1 0 HI0933-like protein Aha1_N PF09229.6 AIN97201.1 - 8.6e-30 103.3 0.0 1.2e-29 102.8 0.0 1.2 1 0 0 1 1 1 1 Activator of Hsp90 ATPase, N-terminal AHSA1 PF08327.6 AIN97201.1 - 3.1e-17 62.8 0.0 9.1e-17 61.3 0.0 1.8 2 0 0 2 2 2 1 Activator of Hsp90 ATPase homolog 1-like protein RRM_6 PF14259.1 AIN97202.1 - 2.6e-12 46.5 0.0 5e-12 45.6 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 AIN97202.1 - 5e-12 45.2 0.0 8.5e-12 44.5 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 AIN97202.1 - 1.6e-06 27.8 0.0 3.8e-06 26.6 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Sua5_yciO_yrdC PF01300.13 AIN97203.1 - 0.092 11.9 0.3 0.4 9.8 0.1 2.1 2 0 0 2 2 2 0 Telomere recombination Pkinase PF00069.20 AIN97207.1 - 9e-56 188.8 0.0 1e-55 188.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AIN97207.1 - 6e-24 84.5 0.0 8.6e-24 84.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 AIN97207.1 - 0.0014 18.4 0.1 0.0078 15.9 0.0 2.1 2 1 0 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 AIN97207.1 - 0.0032 17.0 0.0 0.0062 16.1 0.0 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase Kdo PF06293.9 AIN97207.1 - 0.076 12.0 0.0 0.14 11.2 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family UDPGT PF00201.13 AIN97207.1 - 0.19 10.2 0.0 0.27 9.7 0.0 1.1 1 0 0 1 1 1 0 UDP-glucoronosyl and UDP-glucosyl transferase CoaE PF01121.15 AIN97209.1 - 2e-21 76.1 0.1 6e-06 25.7 0.0 4.1 4 0 0 4 4 4 4 Dephospho-CoA kinase MobB PF03205.9 AIN97209.1 - 0.0085 15.8 0.0 0.017 14.8 0.0 1.5 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_18 PF13238.1 AIN97209.1 - 0.029 14.6 0.0 0.55 10.5 0.0 2.2 2 0 0 2 2 2 0 AAA domain GTP_EFTU PF00009.22 AIN97209.1 - 0.1 12.0 0.1 0.18 11.2 0.1 1.5 1 0 0 1 1 1 0 Elongation factor Tu GTP binding domain RRM_6 PF14259.1 AIN97210.1 - 0.003 17.5 0.0 0.0097 15.8 0.0 1.9 1 1 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) DUF866 PF05907.8 AIN97211.1 - 0.0032 16.9 0.7 0.062 12.7 0.1 2.1 2 0 0 2 2 2 1 Eukaryotic protein of unknown function (DUF866) DUF35_N PF12172.3 AIN97211.1 - 0.057 13.3 5.1 0.18 11.7 0.9 2.5 2 0 0 2 2 2 0 Rubredoxin-like zinc ribbon domain (DUF35_N) Telomere_Sde2_2 PF13297.1 AIN97211.1 - 0.15 11.3 0.1 0.24 10.6 0.0 1.4 1 0 0 1 1 1 0 Telomere stability C-terminal RRN7 PF11781.3 AIN97211.1 - 0.8 9.2 6.2 5.2 6.6 0.4 2.9 3 0 0 3 3 3 0 RNA polymerase I-specific transcription initiation factor Rrn7 DUF4379 PF14311.1 AIN97212.1 - 1.3e-18 66.4 9.6 1.3e-11 44.1 0.7 2.9 2 1 0 2 2 2 2 Domain of unknown function (DUF4379) SprT-like PF10263.4 AIN97212.1 - 0.0013 18.4 2.5 0.4 10.3 0.4 2.3 2 0 0 2 2 2 2 SprT-like family Elf1 PF05129.8 AIN97212.1 - 0.0015 18.1 1.3 1.3 8.7 0.1 3.1 3 0 0 3 3 3 1 Transcription elongation factor Elf1 like Zn_Tnp_IS1595 PF12760.2 AIN97212.1 - 0.015 15.0 8.6 0.3 10.9 1.6 3.3 3 0 0 3 3 3 0 Transposase zinc-ribbon domain zf-ZPR1 PF03367.8 AIN97212.1 - 0.092 11.8 0.0 0.18 10.9 0.0 1.5 1 0 0 1 1 1 0 ZPR1 zinc-finger domain Zn-ribbon_8 PF09723.5 AIN97212.1 - 0.43 10.5 5.6 16 5.5 0.3 3.2 3 0 0 3 3 3 0 Zinc ribbon domain DUF2296 PF10058.4 AIN97212.1 - 0.54 10.0 3.3 21 4.9 0.0 3.1 3 0 0 3 3 3 0 Predicted integral membrane metal-binding protein (DUF2296) zinc_ribbon_2 PF13240.1 AIN97212.1 - 1.2 8.7 9.7 4 7.0 0.0 3.3 3 0 0 3 3 3 0 zinc-ribbon domain zf-HC5HC2H PF13771.1 AIN97212.1 - 1.8 8.7 5.7 7.3 6.8 0.4 2.7 2 1 0 3 3 2 0 PHD-like zinc-binding domain zf-C2H2_4 PF13894.1 AIN97212.1 - 3 8.3 7.7 22 5.7 0.2 4.0 4 0 0 4 4 4 0 C2H2-type zinc finger zf-C3HC4_3 PF13920.1 AIN97212.1 - 5.5 6.7 7.1 1.9 8.2 0.1 2.7 2 1 1 3 3 3 0 Zinc finger, C3HC4 type (RING finger) DnaJ PF00226.26 AIN97213.1 - 3.4e-16 58.7 0.1 5.6e-16 58.0 0.1 1.3 1 0 0 1 1 1 1 DnaJ domain DUF446 PF04287.7 AIN97213.1 - 0.047 13.5 0.1 0.088 12.6 0.1 1.4 1 0 0 1 1 1 0 tRNA pseudouridine synthase C DUF4475 PF14753.1 AIN97214.1 - 1.3e-16 60.7 12.5 1.2e-13 51.0 0.7 3.3 3 0 0 3 3 3 3 Domain of unknown function (DUF4475) NOB1_Zn_bind PF08772.6 AIN97214.1 - 0.0075 16.0 0.8 0.0075 16.0 0.5 2.4 2 0 0 2 2 2 1 Nin one binding (NOB1) Zn-ribbon like stn_TNFRSF12A PF12191.3 AIN97214.1 - 0.38 10.7 11.3 0.68 9.9 0.0 3.2 3 0 0 3 3 3 0 Tumour necrosis factor receptor stn_TNFRSF12A_TNFR domain zinc_ribbon_2 PF13240.1 AIN97214.1 - 3.1 7.4 10.4 0.14 11.6 1.5 2.8 2 0 0 2 2 2 0 zinc-ribbon domain zf-ribbon_3 PF13248.1 AIN97214.1 - 7.8 5.8 12.5 0.18 11.0 1.1 3.3 3 1 1 4 4 3 0 zinc-ribbon domain ATP12 PF07542.6 AIN97215.1 - 1.8e-26 92.4 0.0 3.1e-26 91.7 0.0 1.4 1 0 0 1 1 1 1 ATP12 chaperone protein Peptidase_C13 PF01650.13 AIN97216.1 - 3.7e-35 121.4 0.0 7.1e-35 120.5 0.0 1.4 1 0 0 1 1 1 1 Peptidase C13 family TTL PF03133.10 AIN97217.1 - 2.7e-77 259.6 0.0 3.7e-77 259.1 0.0 1.1 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.1 AIN97217.1 - 6.6e-05 21.8 0.0 0.0078 15.0 0.0 3.0 3 0 0 3 3 3 1 YheC/D like ATP-grasp DUF3884 PF13024.1 AIN97217.1 - 0.049 13.0 0.0 0.1 12.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3884) HEAT_2 PF13646.1 AIN97218.1 - 0.08 13.2 1.2 3.6 7.9 0.0 3.4 3 0 0 3 3 3 0 HEAT repeats Nuc_sug_transp PF04142.10 AIN97220.1 - 2.2e-58 197.2 8.6 2.2e-58 197.2 6.0 2.8 2 1 0 2 2 2 1 Nucleotide-sugar transporter TPT PF03151.11 AIN97220.1 - 8.9e-07 28.6 4.1 8.9e-07 28.6 2.9 3.3 3 0 0 3 3 3 1 Triose-phosphate Transporter family EamA PF00892.15 AIN97220.1 - 9.2e-07 28.9 3.3 9.2e-07 28.9 2.3 3.1 3 0 0 3 3 3 1 EamA-like transporter family EmrE PF13536.1 AIN97220.1 - 0.0045 17.1 5.8 0.0045 17.1 4.0 2.5 2 1 0 2 2 2 1 Multidrug resistance efflux transporter Citrate_synt PF00285.16 AIN97224.1 - 4.6e-97 324.9 0.0 5.6e-97 324.6 0.0 1.1 1 0 0 1 1 1 1 Citrate synthase Citrate_synt PF00285.16 AIN97225.1 - 6.1e-99 331.1 0.0 7.8e-99 330.7 0.0 1.1 1 0 0 1 1 1 1 Citrate synthase HEAT PF02985.17 AIN97227.1 - 8.6e-21 72.1 17.6 0.00087 19.1 0.0 10.6 11 0 0 11 11 11 7 HEAT repeat HEAT_2 PF13646.1 AIN97227.1 - 7.4e-20 71.0 14.7 2.1e-06 27.8 0.0 6.7 3 2 1 6 6 6 5 HEAT repeats HEAT_EZ PF13513.1 AIN97227.1 - 7.8e-08 32.5 7.1 0.0034 17.8 0.0 6.6 7 0 0 7 7 7 2 HEAT-like repeat Adaptin_N PF01602.15 AIN97227.1 - 0.00067 18.0 0.1 2 6.6 0.1 3.4 2 1 1 4 4 4 2 Adaptin N terminal region CLASP_N PF12348.3 AIN97227.1 - 0.0051 16.1 0.1 5.5 6.2 0.0 3.8 2 1 2 4 4 4 1 CLASP N terminal Leuk-A4-hydro_C PF09127.6 AIN97227.1 - 0.073 12.6 0.0 0.35 10.4 0.0 2.1 2 0 0 2 2 2 0 Leukotriene A4 hydrolase, C-terminal DUF2063 PF09836.4 AIN97227.1 - 0.075 13.0 0.0 0.26 11.2 0.0 1.9 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2063) PA26 PF04636.8 AIN97228.1 - 2.1e-32 112.4 1.6 5.8e-12 45.0 0.0 3.1 3 0 0 3 3 3 3 PA26 p53-induced protein (sestrin) Pkinase PF00069.20 AIN97229.1 - 1.3e-73 247.4 0.0 1.4e-73 247.2 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AIN97229.1 - 4.6e-39 134.0 0.0 5.5e-39 133.8 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 AIN97229.1 - 1.1e-10 40.9 0.0 1.4e-10 40.6 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 AIN97229.1 - 5.1e-06 26.4 0.1 0.04 13.6 0.0 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.9 AIN97229.1 - 0.0038 16.3 0.1 0.0057 15.7 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 AIN97229.1 - 0.03 13.6 0.0 0.043 13.1 0.0 1.2 1 0 0 1 1 1 0 RIO1 family DUF421 PF04239.7 AIN97229.1 - 0.048 13.1 1.6 0.12 11.9 1.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF421) Choline_kinase PF01633.15 AIN97229.1 - 0.079 12.5 0.0 0.16 11.5 0.0 1.5 1 1 0 1 1 1 0 Choline/ethanolamine kinase Phosducin PF02114.11 AIN97229.1 - 0.085 11.5 0.1 0.12 11.0 0.1 1.2 1 0 0 1 1 1 0 Phosducin YukC PF10140.4 AIN97229.1 - 0.094 11.2 0.0 0.12 10.9 0.0 1.1 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukC Seadorna_VP7 PF07387.6 AIN97229.1 - 0.11 11.3 0.0 0.19 10.5 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 Ribosomal_L1 PF00687.16 AIN97231.1 - 9.1e-47 159.2 3.3 1.1e-46 158.9 2.3 1.0 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family Peptidase_M41 PF01434.13 AIN97232.1 - 1.8e-49 168.1 1.3 2.4e-49 167.6 0.9 1.2 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.24 AIN97232.1 - 2.2e-39 134.6 0.0 4e-39 133.8 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 AIN97232.1 - 1.1e-05 25.5 1.4 0.00038 20.5 0.7 2.8 1 1 1 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 AIN97232.1 - 0.00029 20.9 0.2 0.0044 17.1 0.1 2.8 1 1 1 2 2 2 1 AAA domain AAA_17 PF13207.1 AIN97232.1 - 0.00029 21.6 0.0 0.001 19.8 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 AIN97232.1 - 0.00038 20.1 0.1 0.0018 17.9 0.1 2.2 1 0 0 1 1 1 1 Part of AAA domain AAA_5 PF07728.9 AIN97232.1 - 0.00046 19.9 0.2 0.0025 17.5 0.1 2.3 2 1 0 2 2 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 AIN97232.1 - 0.00049 20.0 0.1 0.0023 17.8 0.1 2.3 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_25 PF13481.1 AIN97232.1 - 0.0021 17.5 1.5 0.044 13.1 0.1 2.4 1 1 1 2 2 2 1 AAA domain Peptidase_M50B PF13398.1 AIN97232.1 - 0.0023 17.3 0.0 0.005 16.2 0.0 1.5 1 0 0 1 1 1 1 Peptidase M50B-like TIP49 PF06068.8 AIN97232.1 - 0.0079 14.9 0.0 0.018 13.8 0.0 1.5 1 0 0 1 1 1 1 TIP49 C-terminus Sigma54_activat PF00158.21 AIN97232.1 - 0.009 15.4 0.0 0.028 13.8 0.0 1.9 1 1 0 1 1 1 1 Sigma-54 interaction domain RuvB_N PF05496.7 AIN97232.1 - 0.02 13.9 0.7 0.074 12.0 0.0 2.3 3 0 0 3 3 3 0 Holliday junction DNA helicase ruvB N-terminus IstB_IS21 PF01695.12 AIN97232.1 - 0.024 14.0 0.1 0.049 13.0 0.1 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein Zeta_toxin PF06414.7 AIN97232.1 - 0.031 13.3 0.2 0.3 10.1 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin AAA_14 PF13173.1 AIN97232.1 - 0.04 13.8 0.0 0.078 12.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain DUF2075 PF09848.4 AIN97232.1 - 0.057 12.3 0.1 0.085 11.8 0.1 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) NACHT PF05729.7 AIN97232.1 - 0.09 12.4 0.2 0.68 9.5 0.1 2.4 2 0 0 2 2 2 0 NACHT domain KaiC PF06745.8 AIN97232.1 - 0.095 11.8 0.1 0.24 10.4 0.1 1.6 1 0 0 1 1 1 0 KaiC Sigma54_activ_2 PF14532.1 AIN97232.1 - 0.11 12.5 0.0 0.28 11.2 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_18 PF13238.1 AIN97232.1 - 0.15 12.3 0.1 0.49 10.7 0.0 1.8 2 0 0 2 2 2 0 AAA domain Dpy-30 PF05186.8 AIN97233.1 - 2.9e-11 42.6 0.3 4.6e-11 42.0 0.2 1.4 1 0 0 1 1 1 1 Dpy-30 motif Ribosomal_S27e PF01667.12 AIN97234.1 - 4.1e-22 77.4 2.8 5.1e-22 77.1 2.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S27 IBR PF01485.16 AIN97234.1 - 0.0015 18.3 1.4 0.0021 17.8 1.0 1.2 1 0 0 1 1 1 1 IBR domain Zn_Tnp_IS1595 PF12760.2 AIN97234.1 - 0.0081 15.9 1.9 0.012 15.3 1.3 1.4 1 0 0 1 1 1 1 Transposase zinc-ribbon domain FYVE_2 PF02318.11 AIN97234.1 - 0.012 15.4 1.3 0.015 15.2 0.9 1.1 1 0 0 1 1 1 0 FYVE-type zinc finger Cbl_N3 PF02762.9 AIN97234.1 - 0.06 12.9 0.0 0.07 12.7 0.0 1.2 1 0 0 1 1 1 0 CBL proto-oncogene N-terminus, SH2-like domain HypA PF01155.14 AIN97234.1 - 0.099 12.3 1.3 0.12 12.0 0.9 1.2 1 0 0 1 1 1 0 Hydrogenase expression/synthesis hypA family zinc_ribbon_4 PF13717.1 AIN97234.1 - 0.22 11.2 4.4 4.6 7.0 3.0 2.3 1 1 0 1 1 1 0 zinc-ribbon domain Elf1 PF05129.8 AIN97234.1 - 0.3 10.8 2.8 0.44 10.2 1.9 1.2 1 0 0 1 1 1 0 Transcription elongation factor Elf1 like zinc_ribbon_5 PF13719.1 AIN97234.1 - 0.4 10.3 4.6 6.6 6.4 3.2 2.3 1 1 0 1 1 1 0 zinc-ribbon domain Mu-like_Com PF10122.4 AIN97234.1 - 0.53 9.3 7.0 0.38 9.8 0.1 2.3 1 1 1 2 2 2 0 Mu-like prophage protein Com Zn_Tnp_IS1 PF03811.8 AIN97234.1 - 0.54 9.7 7.8 2.2 7.8 5.4 2.0 1 1 0 1 1 1 0 InsA N-terminal domain FYVE PF01363.16 AIN97235.1 - 9.7e-20 70.2 7.3 9.7e-20 70.2 5.0 4.7 3 2 1 4 4 4 1 FYVE zinc finger zf-RanBP PF00641.13 AIN97235.1 - 9.2e-14 50.2 62.7 1.5e-06 27.2 1.4 6.7 7 0 0 7 7 7 5 Zn-finger in Ran binding protein and others DZR PF12773.2 AIN97235.1 - 6.6e-05 22.6 43.3 0.021 14.6 4.5 5.8 4 2 1 5 5 5 4 Double zinc ribbon DUF1675 PF07897.6 AIN97235.1 - 0.26 11.1 8.4 1.7 8.4 1.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1675) RRM_1 PF00076.17 AIN97236.1 - 3.2e-18 65.1 0.0 7.1e-18 64.0 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 AIN97236.1 - 5.7e-13 48.6 0.0 1.3e-12 47.5 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 AIN97236.1 - 1.4e-11 44.0 0.0 3.6e-11 42.7 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 AIN97236.1 - 0.0018 18.0 0.0 0.0056 16.4 0.0 1.8 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif Suf PF05843.9 AIN97236.1 - 1.3 8.6 11.8 0.24 11.0 4.2 2.0 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) ECH PF00378.15 AIN97237.1 - 7.1e-28 97.3 0.7 5e-27 94.5 0.2 1.9 1 1 0 2 2 2 1 Enoyl-CoA hydratase/isomerase family PapD-like PF14874.1 AIN97238.1 - 2.3e-12 46.7 2.5 0.0037 17.1 0.0 5.4 5 0 0 5 5 5 3 Flagellar-associated PapD-like Motile_Sperm PF00635.21 AIN97238.1 - 0.00075 19.1 1.9 0.027 14.1 0.0 4.4 7 0 0 7 7 7 1 MSP (Major sperm protein) domain PapD_N PF00345.15 AIN97238.1 - 0.0016 18.2 0.0 0.68 9.7 0.0 3.4 3 0 0 3 3 3 2 Pili and flagellar-assembly chaperone, PapD N-terminal domain Transglut_C PF00927.17 AIN97238.1 - 0.44 10.6 2.1 10 6.1 0.0 4.2 7 0 0 7 7 7 0 Transglutaminase family, C-terminal ig like domain V-ATPase_C PF03223.10 AIN97239.1 - 1.5e-91 307.1 0.8 1.7e-91 306.9 0.6 1.0 1 0 0 1 1 1 1 V-ATPase subunit C Birna_VP3 PF01767.11 AIN97240.1 - 0.0081 15.8 3.7 0.013 15.0 2.6 1.3 1 0 0 1 1 1 1 Birnavirus VP3 protein MRP-S26 PF14943.1 AIN97240.1 - 0.011 15.3 9.4 0.017 14.6 6.5 1.3 1 0 0 1 1 1 0 Mitochondrial ribosome subunit S26 DOR PF14839.1 AIN97240.1 - 1.8 8.2 5.9 3.9 7.1 4.1 1.5 1 0 0 1 1 1 0 DOR family TBCC PF07986.7 AIN97242.1 - 9e-34 115.4 0.1 1.4e-33 114.7 0.1 1.3 1 0 0 1 1 1 1 Tubulin binding cofactor C FOP_dimer PF09398.5 AIN97242.1 - 4.1e-05 23.4 0.0 7.4e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 FOP N terminal dimerisation domain CAP_C PF08603.6 AIN97242.1 - 0.0042 16.4 1.5 0.011 15.1 0.1 2.0 2 0 0 2 2 2 1 Adenylate cyclase associated (CAP) C terminal SecA_DEAD PF07517.9 AIN97242.1 - 0.084 12.1 0.0 0.1 11.8 0.0 1.2 1 0 0 1 1 1 0 SecA DEAD-like domain MRI PF15325.1 AIN97242.1 - 4.4 8.3 11.4 9.7 7.2 4.9 2.6 2 0 0 2 2 2 0 Modulator of retrovirus infection Mnd1 PF03962.10 AIN97243.1 - 0.014 15.0 1.6 0.014 15.0 1.1 3.1 3 0 0 3 3 3 0 Mnd1 family CASP_C PF08172.7 AIN97243.1 - 0.028 13.4 9.5 0.1 11.5 6.5 2.2 1 1 0 1 1 1 0 CASP C terminal LemA PF04011.7 AIN97243.1 - 0.15 11.1 9.1 0.0097 15.0 2.5 1.8 2 0 0 2 2 2 0 LemA family FlaC_arch PF05377.6 AIN97243.1 - 0.22 11.4 3.4 25 4.8 0.2 3.4 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) DUF972 PF06156.8 AIN97243.1 - 0.42 10.9 0.1 0.42 10.9 0.1 3.8 3 1 0 3 3 3 0 Protein of unknown function (DUF972) Lectin_N PF03954.9 AIN97243.1 - 1.7 8.0 6.4 1.8 7.9 0.4 3.1 1 1 1 2 2 2 0 Hepatic lectin, N-terminal domain Phage_GP20 PF06810.6 AIN97243.1 - 2.5 7.5 9.7 1.3 8.3 0.3 3.0 3 0 0 3 3 3 0 Phage minor structural protein GP20 APG6 PF04111.7 AIN97243.1 - 2.9 6.8 23.8 0.94 8.4 1.9 3.1 3 0 0 3 3 3 0 Autophagy protein Apg6 Med9 PF07544.8 AIN97243.1 - 4.9 6.9 8.2 4 7.2 1.5 3.1 2 1 1 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 Aconitase PF00330.15 AIN97244.1 - 6.1e-140 466.7 0.0 7.9e-140 466.3 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 AIN97244.1 - 9.2e-42 142.2 0.0 1.7e-41 141.4 0.0 1.4 1 0 0 1 1 1 1 Aconitase C-terminal domain PPR_2 PF13041.1 AIN97245.1 - 0.044 13.7 0.0 1.4 8.9 0.0 2.8 3 0 0 3 3 3 0 PPR repeat family CAP_N PF01213.14 AIN97245.1 - 0.052 12.8 4.5 1.5 8.0 0.1 2.3 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal PPR_1 PF12854.2 AIN97245.1 - 0.11 12.0 0.2 0.33 10.4 0.1 1.8 1 0 0 1 1 1 0 PPR repeat BTB_2 PF02214.17 AIN97246.1 - 7.9e-13 48.4 0.0 1.2e-12 47.7 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain UDG PF03167.14 AIN97247.1 - 7.8e-22 77.3 0.0 1.1e-21 76.9 0.0 1.2 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily DUF566 PF04484.7 AIN97247.1 - 3.6 7.0 8.5 5.4 6.4 5.9 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF566) WD40 PF00400.27 AIN97248.1 - 5.4e-58 190.9 19.8 1.6e-10 40.4 0.5 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 AIN97248.1 - 0.036 12.2 3.8 2 6.4 0.1 2.7 2 1 1 3 3 3 0 Nucleoporin Nup120/160 CENP-F_leu_zip PF10473.4 AIN97248.1 - 0.19 11.5 17.6 0.32 10.8 12.2 1.3 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 CDC37_N PF03234.9 AIN97248.1 - 0.78 10.0 4.8 1.4 9.2 3.3 1.3 1 0 0 1 1 1 0 Cdc37 N terminal kinase binding DUF904 PF06005.7 AIN97248.1 - 5.3 7.4 10.9 20 5.5 0.3 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF904) CAP_GLY PF01302.20 AIN97249.1 - 2.9e-22 78.1 0.6 5.4e-22 77.2 0.4 1.5 1 0 0 1 1 1 1 CAP-Gly domain Ubiquitin_2 PF14560.1 AIN97249.1 - 1.2e-21 76.7 0.0 2.2e-21 75.8 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-like domain ubiquitin PF00240.18 AIN97249.1 - 0.004 16.5 0.0 0.04 13.3 0.0 2.1 2 0 0 2 2 2 1 Ubiquitin family Peptidase_S10 PF00450.17 AIN97250.1 - 1.3e-106 357.3 0.7 1.6e-106 357.0 0.5 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Abhydrolase_6 PF12697.2 AIN97250.1 - 0.00027 20.8 0.0 0.0014 18.5 0.0 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Collar PF07484.7 AIN97250.1 - 0.029 14.1 0.3 1.2 9.0 0.0 2.9 3 0 0 3 3 3 0 Phage Tail Collar Domain Peptidase_S9 PF00326.16 AIN97250.1 - 0.066 12.4 0.0 0.66 9.1 0.0 2.1 2 0 0 2 2 2 0 Prolyl oligopeptidase family PAP2 PF01569.16 AIN97251.1 - 8e-20 70.8 5.6 8e-20 70.8 3.9 2.1 2 0 0 2 2 2 1 PAP2 superfamily PAP2 PF01569.16 AIN97252.1 - 2.2e-17 62.9 1.6 2.2e-17 62.9 1.1 2.1 2 1 0 2 2 2 1 PAP2 superfamily C_GCAxxG_C_C PF09719.5 AIN97252.1 - 0.094 12.5 0.0 0.2 11.4 0.0 1.4 1 0 0 1 1 1 0 Putative redox-active protein (C_GCAxxG_C_C) ABC_membrane PF00664.18 AIN97252.1 - 0.18 11.1 1.2 1.7 7.9 0.4 2.4 3 0 0 3 3 3 0 ABC transporter transmembrane region AAA_16 PF13191.1 AIN97253.1 - 0.011 15.7 0.1 0.011 15.7 0.1 3.9 4 1 1 5 5 5 0 AAA ATPase domain Tom5 PF10642.4 AIN97253.1 - 0.037 13.6 0.0 0.094 12.3 0.0 1.7 1 0 0 1 1 1 0 Mitochondrial import receptor subunit or translocase DUF4404 PF14357.1 AIN97253.1 - 0.34 11.3 2.8 7.8 6.9 0.2 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4404) Tctex-1 PF03645.8 AIN97254.1 - 2.3e-21 75.5 0.1 5.6e-21 74.3 0.0 1.6 2 0 0 2 2 2 1 Tctex-1 family RNA_pol_Rpo13 PF12136.3 AIN97254.1 - 2.9 7.6 9.0 33 4.2 0.0 2.5 2 0 0 2 2 2 0 RNA polymerase Rpo13 subunit HTH domain GTP_EFTU PF00009.22 AIN97255.1 - 7.4e-55 185.3 0.3 1.2e-54 184.5 0.2 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 AIN97255.1 - 5.5e-19 68.1 0.3 1.5e-17 63.5 0.0 2.9 2 1 0 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 AIN97255.1 - 3.7e-07 30.1 0.5 9.6e-07 28.8 0.3 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 AIN97255.1 - 0.0015 18.4 0.0 0.0033 17.3 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D4 PF14578.1 AIN97255.1 - 0.029 13.9 1.7 0.033 13.8 0.1 1.9 2 0 0 2 2 2 0 Elongation factor Tu domain 4 Miro PF08477.8 AIN97255.1 - 0.039 14.4 0.1 0.12 12.8 0.0 1.8 1 0 0 1 1 1 0 Miro-like protein PduV-EutP PF10662.4 AIN97255.1 - 0.044 13.2 1.2 2.4 7.6 0.9 2.4 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_29 PF13555.1 AIN97255.1 - 0.1 12.1 0.1 0.34 10.4 0.0 1.8 2 0 0 2 2 2 0 P-loop containing region of AAA domain zf-met PF12874.2 AIN97257.1 - 1.5e-07 31.3 0.9 2.4e-07 30.7 0.6 1.4 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 AIN97257.1 - 3.3e-07 30.2 3.1 5.3e-07 29.6 2.2 1.4 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.2 AIN97257.1 - 0.00019 21.5 0.1 0.00025 21.1 0.1 1.1 1 0 0 1 1 1 1 C2H2 type zinc-finger (2 copies) zf-C2H2 PF00096.21 AIN97257.1 - 0.069 13.5 0.3 0.13 12.6 0.2 1.5 1 0 0 1 1 1 0 Zinc finger, C2H2 type DUF3128 PF11326.3 AIN97257.1 - 0.075 13.1 0.5 0.11 12.6 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3128) zf-DBF PF07535.7 AIN97257.1 - 0.12 12.0 0.9 0.18 11.4 0.6 1.3 1 0 0 1 1 1 0 DBF zinc finger zf-U1 PF06220.7 AIN97257.1 - 0.14 11.7 1.0 0.22 11.1 0.7 1.3 1 0 0 1 1 1 0 U1 zinc finger zf-C2H2_6 PF13912.1 AIN97257.1 - 2.6 8.0 5.0 8.8 6.3 3.5 2.0 1 1 0 1 1 1 0 C2H2-type zinc finger PDZ_2 PF13180.1 AIN97258.1 - 4.8e-05 23.1 0.0 0.00013 21.8 0.0 1.6 1 0 0 1 1 1 1 PDZ domain RNA_pol_Rpb5_C PF01191.14 AIN97259.1 - 1.2e-31 108.0 0.6 2.3e-31 107.2 0.4 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb5, C-terminal domain RNA_pol_Rpb5_N PF03871.9 AIN97259.1 - 4e-13 49.5 0.1 2.5e-12 47.0 0.0 2.2 1 1 0 1 1 1 1 RNA polymerase Rpb5, N-terminal domain RNA_pol_Rpb5_C PF01191.14 AIN97260.1 - 4.4e-24 83.8 0.1 1e-23 82.7 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb5, C-terminal domain RNA_pol_Rpb5_N PF03871.9 AIN97260.1 - 1.1e-08 35.3 0.0 0.00019 21.7 0.0 2.4 2 0 0 2 2 2 2 RNA polymerase Rpb5, N-terminal domain DUF3182 PF11379.3 AIN97260.1 - 0.11 11.1 0.0 0.19 10.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3182) Ribosomal_S8 PF00410.14 AIN97261.1 - 3.3e-11 43.1 0.0 4.5e-11 42.7 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S8 FKS1_dom1 PF14288.1 AIN97261.1 - 0.11 12.4 0.1 0.41 10.5 0.0 1.9 1 1 0 2 2 2 0 1,3-beta-glucan synthase subunit FKS1, domain-1 CDP-OH_P_transf PF01066.16 AIN97262.1 - 2.5e-25 88.7 0.7 2.5e-25 88.7 0.5 3.0 3 1 0 3 3 3 1 CDP-alcohol phosphatidyltransferase HEAT_EZ PF13513.1 AIN97263.1 - 0.015 15.7 25.7 2.3 8.8 1.3 9.4 8 1 1 9 9 9 0 HEAT-like repeat WD40 PF00400.27 AIN97264.1 - 5.2e-28 95.8 25.8 5e-08 32.5 0.0 12.3 14 0 0 14 14 14 7 WD domain, G-beta repeat Utp12 PF04003.7 AIN97264.1 - 3.7e-07 30.0 0.0 8.4e-07 28.8 0.0 1.7 1 0 0 1 1 1 1 Dip2/Utp12 Family DUF1513 PF07433.6 AIN97264.1 - 0.00045 19.2 0.6 0.12 11.1 0.0 3.2 3 0 0 3 3 3 2 Protein of unknown function (DUF1513) 14-3-3 PF00244.15 AIN97265.1 - 0.086 11.9 0.1 1.1 8.2 0.0 2.3 2 0 0 2 2 2 0 14-3-3 protein RRN7 PF11781.3 AIN97266.1 - 0.22 11.0 1.8 0.54 9.8 1.3 1.6 1 0 0 1 1 1 0 RNA polymerase I-specific transcription initiation factor Rrn7 ACBP PF00887.14 AIN97267.1 - 0.0076 15.8 0.0 0.018 14.7 0.0 1.6 1 0 0 1 1 1 1 Acyl CoA binding protein DUF2201_N PF13203.1 AIN97268.1 - 0.097 11.8 0.5 0.15 11.1 0.4 1.2 1 0 0 1 1 1 0 Putative metallopeptidase domain Pro_isomerase PF00160.16 AIN97269.1 - 2e-32 112.5 0.0 4.7e-32 111.3 0.0 1.6 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Ras PF00071.17 AIN97270.1 - 8.6e-54 181.2 2.1 1.2e-52 177.6 1.4 2.0 1 1 0 1 1 1 1 Ras family Miro PF08477.8 AIN97270.1 - 1.7e-21 76.9 0.0 3.4e-21 75.9 0.0 1.5 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 AIN97270.1 - 5e-12 45.4 0.0 5.9e-12 45.1 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 AIN97270.1 - 7.3e-08 31.8 0.0 8.8e-08 31.5 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 AIN97270.1 - 6e-05 22.5 0.3 0.0016 17.9 0.2 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 AIN97270.1 - 7.5e-05 22.6 0.0 0.00013 21.9 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.1 AIN97270.1 - 0.0049 17.0 0.0 0.0075 16.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.1 AIN97270.1 - 0.0054 16.3 0.1 0.012 15.2 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 AIN97270.1 - 0.007 16.3 0.2 0.011 15.7 0.1 1.6 1 1 0 1 1 1 1 AAA ATPase domain DUF258 PF03193.11 AIN97270.1 - 0.014 14.5 0.1 0.029 13.5 0.1 1.5 1 1 0 1 1 1 0 Protein of unknown function, DUF258 cobW PF02492.14 AIN97270.1 - 0.015 14.7 0.1 2.6 7.4 0.0 2.3 1 1 1 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_10 PF12846.2 AIN97270.1 - 0.019 14.4 0.0 0.034 13.6 0.0 1.5 1 1 0 1 1 1 0 AAA-like domain MobB PF03205.9 AIN97270.1 - 0.024 14.3 0.6 0.1 12.3 0.0 2.3 2 1 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B NTPase_1 PF03266.10 AIN97270.1 - 0.032 13.9 0.0 0.044 13.4 0.0 1.3 1 0 0 1 1 1 0 NTPase ATP_bind_1 PF03029.12 AIN97270.1 - 0.039 13.4 0.2 1.1 8.8 0.0 2.3 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein AAA_25 PF13481.1 AIN97270.1 - 0.053 12.9 0.0 0.27 10.5 0.0 1.9 1 1 1 2 2 2 0 AAA domain PduV-EutP PF10662.4 AIN97270.1 - 0.053 12.9 0.1 0.18 11.2 0.0 2.0 2 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation NACHT PF05729.7 AIN97270.1 - 0.056 13.1 0.0 0.089 12.4 0.0 1.3 1 0 0 1 1 1 0 NACHT domain SRPRB PF09439.5 AIN97270.1 - 0.059 12.5 0.0 0.096 11.8 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_5 PF07728.9 AIN97270.1 - 0.065 12.9 0.0 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Arch_ATPase PF01637.13 AIN97270.1 - 0.073 12.7 0.0 0.12 12.0 0.0 1.3 1 0 0 1 1 1 0 Archaeal ATPase RNA_helicase PF00910.17 AIN97270.1 - 0.096 12.8 0.0 0.51 10.5 0.0 2.1 1 1 0 1 1 1 0 RNA helicase AAA PF00004.24 AIN97270.1 - 0.14 12.3 0.0 0.23 11.6 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Glyco_trans_1_4 PF13692.1 AIN97271.1 - 6.8e-10 39.2 0.0 1.7e-09 37.9 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferases group 1 PPR_2 PF13041.1 AIN97272.1 - 0.00083 19.2 0.0 0.49 10.4 0.0 3.3 2 1 1 3 3 3 2 PPR repeat family PPR PF01535.15 AIN97272.1 - 0.12 12.3 0.0 11 6.2 0.0 3.5 3 0 0 3 3 3 0 PPR repeat PPR_3 PF13812.1 AIN97272.1 - 0.2 12.0 12.8 63 4.2 0.0 7.5 8 0 0 8 8 8 0 Pentatricopeptide repeat domain WD40 PF00400.27 AIN97273.1 - 1.3e-09 37.5 24.4 0.00014 21.6 0.2 7.5 8 1 0 8 8 8 4 WD domain, G-beta repeat CD52 PF15116.1 AIN97273.1 - 2.7 7.8 7.3 31 4.4 3.7 3.0 2 0 0 2 2 2 0 CAMPATH-1 antigen Myosin_TH1 PF06017.8 AIN97274.1 - 0.09 12.0 0.0 0.16 11.2 0.0 1.3 1 0 0 1 1 1 0 Myosin tail Nrap PF03813.9 AIN97275.1 - 2.9e-74 250.2 0.0 4.5e-74 249.6 0.0 1.1 1 0 0 1 1 1 1 Nrap protein Zn-ribbon_8 PF09723.5 AIN97276.1 - 0.064 13.2 1.1 0.39 10.7 0.3 2.5 2 0 0 2 2 2 0 Zinc ribbon domain Mannosyl_trans2 PF04188.8 AIN97277.1 - 1.3e-34 119.9 31.3 2.2e-20 73.0 10.6 4.1 4 0 0 4 4 4 4 Mannosyltransferase (PIG-V)) IQ PF00612.22 AIN97278.1 - 0.012 15.2 4.7 1.9 8.3 0.0 3.1 2 0 0 2 2 2 0 IQ calmodulin-binding motif Cupin_8 PF13621.1 AIN97279.1 - 0.11 11.9 2.3 0.12 11.7 1.6 1.2 1 0 0 1 1 1 0 Cupin-like domain PIN_2 PF10130.4 AIN97279.1 - 1.2 9.1 6.5 1.3 9.0 3.6 1.6 1 1 0 1 1 1 0 PIN domain V_ATPase_I PF01496.14 AIN97279.1 - 2.9 5.6 10.1 3.5 5.3 7.0 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family AAA_23 PF13476.1 AIN97279.1 - 7.5 6.8 8.9 11 6.3 6.2 1.3 1 0 0 1 1 1 0 AAA domain IncA PF04156.9 AIN97279.1 - 8.6 5.9 11.1 13 5.3 7.7 1.3 1 0 0 1 1 1 0 IncA protein UDPGP PF01704.13 AIN97280.1 - 6.9e-90 301.5 0.0 1.6e-89 300.3 0.0 1.5 1 1 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase Mito_carr PF00153.22 AIN97281.1 - 1.9e-19 69.1 4.2 3.7e-10 39.3 0.0 4.1 3 1 0 3 3 3 3 Mitochondrial carrier protein Robl_LC7 PF03259.12 AIN97282.1 - 1.4e-21 75.8 0.0 1.7e-21 75.5 0.0 1.0 1 0 0 1 1 1 1 Roadblock/LC7 domain SlyX PF04102.7 AIN97283.1 - 0.011 16.0 2.7 0.011 16.0 1.9 5.1 5 0 0 5 5 5 0 SlyX HALZ PF02183.13 AIN97283.1 - 0.013 15.2 0.4 3.5 7.4 0.0 3.8 3 0 0 3 3 3 0 Homeobox associated leucine zipper FlaC_arch PF05377.6 AIN97283.1 - 0.22 11.4 0.5 1.1e+02 2.7 0.0 3.7 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) Phage_GP20 PF06810.6 AIN97283.1 - 5.7 6.3 7.2 7.6 5.9 0.2 2.6 2 0 0 2 2 2 0 Phage minor structural protein GP20 PhoD PF09423.5 AIN97284.1 - 2e-08 33.2 0.0 4.2e-07 28.8 0.0 2.4 1 1 0 1 1 1 1 PhoD-like phosphatase Hydantoinase_B PF02538.9 AIN97285.1 - 9.3e-173 575.2 0.0 3.6e-170 566.6 0.0 2.1 2 0 0 2 2 2 2 Hydantoinase B/oxoprolinase Hydantoinase_A PF01968.13 AIN97285.1 - 9.9e-86 287.4 0.9 2.3e-85 286.1 0.6 1.7 1 0 0 1 1 1 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.8 AIN97285.1 - 3.1e-51 173.3 0.5 1.3e-49 168.1 0.0 2.5 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase N-terminal region SynMuv_product PF06047.6 AIN97285.1 - 0.003 17.2 0.1 0.0071 16.0 0.1 1.5 1 0 0 1 1 1 1 Ras-induced vulval development antagonist Nuc_N PF14448.1 AIN97285.1 - 0.07 12.7 0.0 0.18 11.4 0.0 1.6 1 0 0 1 1 1 0 Nuclease N terminal Peptidase_M15_3 PF08291.6 AIN97285.1 - 0.13 12.0 0.0 0.32 10.8 0.0 1.6 1 0 0 1 1 1 0 Peptidase M15 DUF3157 PF11355.3 AIN97286.1 - 0.036 13.3 0.1 0.07 12.4 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3157) Peptidase_C2 PF00648.16 AIN97287.1 - 2.8e-12 46.2 0.0 5e-11 42.1 0.0 2.1 1 1 0 1 1 1 1 Calpain family cysteine protease Luteo_coat PF00894.13 AIN97287.1 - 0.094 12.4 0.0 0.19 11.4 0.0 1.4 1 0 0 1 1 1 0 Luteovirus coat protein Vps16_C PF04840.7 AIN97288.1 - 1.1e-25 90.3 1.3 1.1e-13 50.8 0.0 2.7 3 0 0 3 3 3 2 Vps16, C-terminal region Vps16_N PF04841.8 AIN97288.1 - 1.4e-18 66.6 0.0 2.7e-18 65.7 0.0 1.4 1 0 0 1 1 1 1 Vps16, N-terminal region DUF169 PF02596.10 AIN97288.1 - 0.0048 16.3 0.4 1.6 8.0 0.0 3.0 3 1 0 3 3 3 2 Uncharacterised ArCR, COG2043 Pkinase PF00069.20 AIN97289.1 - 7.3e-72 241.6 0.0 8.4e-72 241.4 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AIN97289.1 - 1.2e-36 126.1 0.0 1.5e-36 125.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 AIN97289.1 - 7.6e-07 28.3 0.0 1.2e-06 27.7 0.0 1.4 1 1 0 1 1 1 1 Kinase-like APH PF01636.18 AIN97289.1 - 0.03 14.0 0.0 0.062 13.0 0.0 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.9 AIN97289.1 - 0.049 12.6 0.0 0.081 11.9 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family PDEase_I PF00233.14 AIN97290.1 - 5.8e-70 235.7 0.2 5.8e-70 235.7 0.1 1.9 2 0 0 2 2 2 1 3'5'-cyclic nucleotide phosphodiesterase Ank PF00023.25 AIN97291.1 - 2.4e-22 77.5 0.2 2.1e-08 33.5 0.0 3.8 4 0 0 4 4 4 3 Ankyrin repeat Ank_2 PF12796.2 AIN97291.1 - 3.7e-22 78.4 0.1 8.3e-15 54.9 0.0 2.6 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_5 PF13857.1 AIN97291.1 - 3e-21 74.9 0.6 3.4e-09 36.6 0.0 4.4 2 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 AIN97291.1 - 5.9e-18 63.1 0.1 0.00013 21.8 0.0 4.4 4 0 0 4 4 4 3 Ankyrin repeat Ank_4 PF13637.1 AIN97291.1 - 6.4e-17 61.5 1.0 5.3e-11 42.7 0.0 3.7 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Nol1_Nop2_Fmu PF01189.12 AIN97292.1 - 1.7e-24 86.6 0.0 9.9e-24 84.1 0.0 2.0 1 1 0 1 1 1 1 NOL1/NOP2/sun family FtsJ PF01728.14 AIN97292.1 - 3.8e-05 23.7 0.0 7.3e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_26 PF13659.1 AIN97292.1 - 0.0011 18.9 0.0 0.0054 16.7 0.0 2.2 1 0 0 1 1 1 1 Methyltransferase domain zf-AN1 PF01428.11 AIN97293.1 - 2.7e-17 62.3 31.8 5.5e-10 38.9 6.6 2.9 2 1 1 3 3 3 2 AN1-like Zinc finger Transp_Tc5_C PF04236.10 AIN97293.1 - 0.0045 17.1 17.4 0.024 14.8 2.8 2.7 2 0 0 2 2 2 2 Tc5 transposase C-terminal domain zf-HIT PF04438.11 AIN97293.1 - 2.6 7.7 17.8 0.13 11.8 1.6 3.0 3 0 0 3 3 3 0 HIT zinc finger Ras PF00071.17 AIN97294.1 - 5.5e-51 172.1 0.0 1.7e-50 170.5 0.0 1.7 1 1 0 1 1 1 1 Ras family Miro PF08477.8 AIN97294.1 - 6.4e-14 52.4 0.0 1.3e-13 51.4 0.0 1.5 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 AIN97294.1 - 6.9e-11 41.6 0.0 1.8e-09 37.1 0.0 2.1 1 1 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 AIN97294.1 - 4.4e-05 22.7 0.0 5.9e-05 22.3 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region ABC_tran PF00005.22 AIN97294.1 - 0.015 15.6 0.0 0.023 14.9 0.0 1.5 1 1 0 1 1 1 0 ABC transporter MMR_HSR1 PF01926.18 AIN97294.1 - 0.019 14.9 0.0 0.083 12.8 0.0 1.8 1 1 1 2 2 2 0 50S ribosome-binding GTPase AAA_22 PF13401.1 AIN97294.1 - 0.034 14.2 0.0 0.086 12.9 0.0 1.8 1 1 0 1 1 1 0 AAA domain DUF258 PF03193.11 AIN97294.1 - 0.063 12.4 0.0 0.14 11.2 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_24 PF13479.1 AIN97294.1 - 0.098 12.2 0.0 0.14 11.6 0.0 1.6 1 1 0 1 1 1 0 AAA domain zf-C3HC4_3 PF13920.1 AIN97296.1 - 6.4e-17 60.9 11.4 1.1e-16 60.1 7.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 AIN97296.1 - 5.2e-09 35.9 15.1 9.8e-09 35.0 10.5 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 AIN97296.1 - 7.5e-06 25.6 12.9 1.4e-05 24.8 8.9 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 AIN97296.1 - 0.0076 15.9 12.3 0.014 15.0 8.5 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zinc_ribbon_2 PF13240.1 AIN97296.1 - 0.0079 15.6 0.9 0.017 14.5 0.6 1.6 1 0 0 1 1 1 1 zinc-ribbon domain Mannitol_dh PF01232.18 AIN97296.1 - 0.05 13.5 0.0 0.093 12.6 0.0 1.4 1 0 0 1 1 1 0 Mannitol dehydrogenase Rossmann domain DUF1180 PF06679.7 AIN97296.1 - 0.081 12.8 2.1 0.9 9.4 1.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1180) zf-P11 PF03854.9 AIN97296.1 - 0.26 10.7 10.3 0.56 9.7 7.1 1.6 1 1 0 1 1 1 0 P-11 zinc finger DUF605 PF04652.11 AIN97296.1 - 0.56 9.5 6.4 0.81 9.0 4.5 1.2 1 0 0 1 1 1 0 Vta1 like DZR PF12773.2 AIN97296.1 - 2.8 7.8 8.8 18 5.2 6.4 1.8 1 1 0 1 1 1 0 Double zinc ribbon Prok-RING_4 PF14447.1 AIN97296.1 - 3.8 7.1 9.8 18 5.0 6.8 2.0 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 TPR_7 PF13176.1 AIN97297.1 - 0.041 13.6 0.5 0.092 12.5 0.4 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_16 PF13432.1 AIN97297.1 - 0.098 13.3 2.3 0.15 12.7 1.6 1.2 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_4 PF07721.9 AIN97297.1 - 0.12 12.8 0.2 0.3 11.6 0.2 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_10 PF13374.1 AIN97297.1 - 0.15 11.9 0.6 0.32 11.0 0.4 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat Cmc1 PF08583.5 AIN97298.1 - 0.006 16.3 2.6 0.013 15.2 1.8 1.5 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like HalX PF08663.5 AIN97299.1 - 2.8 8.0 12.4 4.2 7.4 0.3 3.3 3 0 0 3 3 3 0 HalX domain NPV_P10 PF05531.7 AIN97299.1 - 4.5 7.5 11.2 0.26 11.5 1.1 3.2 4 0 0 4 4 4 0 Nucleopolyhedrovirus P10 protein NMN_transporter PF04973.7 AIN97300.1 - 0.089 12.2 0.0 0.17 11.3 0.0 1.4 1 0 0 1 1 1 0 Nicotinamide mononucleotide transporter Complex1_LYR PF05347.10 AIN97301.1 - 2.1e-09 37.0 1.4 2.1e-09 37.0 1.0 1.9 2 0 0 2 2 2 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 AIN97301.1 - 1.6e-07 31.4 1.9 1.6e-07 31.4 1.3 1.8 2 0 0 2 2 2 1 Complex1_LYR-like Terminase_3 PF04466.8 AIN97301.1 - 0.0055 15.8 0.1 0.0073 15.4 0.0 1.1 1 0 0 1 1 1 1 Phage terminase large subunit tRNA_edit PF04073.10 AIN97302.1 - 5.5e-16 58.5 0.1 9.2e-16 57.8 0.1 1.4 1 0 0 1 1 1 1 Aminoacyl-tRNA editing domain ProRS-C_1 PF09180.6 AIN97303.1 - 2.8e-23 81.6 2.2 8.1e-23 80.1 1.6 1.9 1 0 0 1 1 1 1 Prolyl-tRNA synthetase, C-terminal tRNA_edit PF04073.10 AIN97303.1 - 4.7e-22 78.1 0.1 8.6e-22 77.2 0.1 1.5 1 0 0 1 1 1 1 Aminoacyl-tRNA editing domain tRNA-synt_2b PF00587.20 AIN97303.1 - 1.2e-15 57.5 0.0 2.3e-15 56.6 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 AIN97303.1 - 5.8e-15 55.0 0.0 2.5e-14 52.9 0.0 2.0 2 0 0 2 2 2 1 Anticodon binding domain SET PF00856.23 AIN97304.1 - 1.5e-08 35.1 0.0 1.2e-07 32.2 0.0 2.2 1 1 0 1 1 1 1 SET domain SAF PF08666.7 AIN97304.1 - 0.13 12.6 0.0 38 4.7 0.0 3.2 3 1 0 3 3 3 0 SAF domain PIH1 PF08190.7 AIN97305.1 - 8.8e-28 97.6 0.5 2.9e-20 72.9 0.0 4.4 4 1 0 4 4 4 3 pre-RNA processing PIH1/Nop17 MCRS_N PF13325.1 AIN97306.1 - 3.5e-05 23.4 0.0 5.6e-05 22.7 0.0 1.2 1 0 0 1 1 1 1 N-terminal region of micro-spherule protein Myb_DNA-binding PF00249.26 AIN97306.1 - 0.037 14.0 0.0 0.071 13.1 0.0 1.5 1 0 0 1 1 1 0 Myb-like DNA-binding domain Complex1_LYR PF05347.10 AIN97306.1 - 0.23 11.2 2.3 0.53 10.1 1.6 1.6 1 0 0 1 1 1 0 Complex 1 protein (LYR family) Mito_carr PF00153.22 AIN97307.1 - 3.1e-34 116.5 6.1 3.8e-14 52.1 0.0 3.4 3 1 0 3 3 3 3 Mitochondrial carrier protein DmpG_comm PF07836.6 AIN97307.1 - 0.24 10.8 1.0 29 4.1 0.0 3.1 3 0 0 3 3 3 0 DmpG-like communication domain Acetyltransf_1 PF00583.19 AIN97308.1 - 3.9e-07 30.0 0.1 0.0013 18.6 0.0 2.4 2 0 0 2 2 2 2 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 AIN97308.1 - 0.0085 16.2 0.0 0.95 9.6 0.0 2.4 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 AIN97308.1 - 0.13 12.2 0.0 0.25 11.2 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Phytochelatin PF05023.9 AIN97309.1 - 0.0019 17.1 0.1 10 5.0 0.0 4.0 4 0 0 4 4 4 3 Phytochelatin synthase CTP_transf_2 PF01467.21 AIN97310.1 - 9.4e-11 42.0 0.0 1.5e-10 41.3 0.0 1.3 1 0 0 1 1 1 1 Cytidylyltransferase CDP-OH_P_transf PF01066.16 AIN97310.1 - 2.4e-05 24.5 1.9 2.4e-05 24.5 1.3 3.5 2 2 0 2 2 2 1 CDP-alcohol phosphatidyltransferase zf-CCCH PF00642.19 AIN97311.1 - 0.00057 19.5 9.8 0.34 10.6 0.0 2.6 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH PF00642.19 AIN97312.1 - 0.0065 16.1 4.1 0.76 9.5 0.3 2.6 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Reo_sigmaC PF04582.7 AIN97313.1 - 0.38 9.8 29.8 0.87 8.6 1.3 4.8 3 1 2 5 5 5 0 Reovirus sigma C capsid protein Tropomyosin_1 PF12718.2 AIN97313.1 - 3.3 7.5 124.5 0.098 12.4 15.4 7.8 3 3 6 9 9 9 0 Tropomyosin like HSP70 PF00012.15 AIN97314.1 - 6.5e-108 361.2 6.3 1e-102 344.0 0.0 2.7 3 0 0 3 3 3 2 Hsp70 protein FGGY_C PF02782.11 AIN97314.1 - 7.1e-07 29.0 1.1 6e-05 22.7 0.0 2.5 2 0 0 2 2 2 2 FGGY family of carbohydrate kinases, C-terminal domain MreB_Mbl PF06723.8 AIN97314.1 - 7e-05 21.5 0.0 0.00034 19.3 0.0 2.0 1 1 0 1 1 1 1 MreB/Mbl protein Herpes_U59 PF04529.7 AIN97314.1 - 0.011 14.6 0.5 0.9 8.3 0.1 2.2 2 0 0 2 2 2 0 Herpesvirus U59 protein DUF2360 PF10152.4 AIN97314.1 - 0.91 9.7 14.1 4.9 7.4 5.1 2.4 2 0 0 2 2 2 0 Predicted coiled-coil domain-containing protein (DUF2360) E1_dh PF00676.15 AIN97315.1 - 5.1e-103 343.9 0.2 5.9e-103 343.6 0.1 1.0 1 0 0 1 1 1 1 Dehydrogenase E1 component DXP_synthase_N PF13292.1 AIN97315.1 - 0.004 16.1 0.4 0.014 14.3 0.0 1.8 2 0 0 2 2 2 1 1-deoxy-D-xylulose-5-phosphate synthase Cyt_c_ox_IV PF12270.3 AIN97316.1 - 0.057 13.1 0.0 0.09 12.5 0.0 1.3 1 0 0 1 1 1 0 Cytochrome c oxidase subunit IV Ribosomal_L34e PF01199.13 AIN97317.1 - 2.3e-28 98.2 3.6 2.3e-28 98.2 2.5 2.2 2 1 0 2 2 2 1 Ribosomal protein L34e NARP1 PF12569.3 AIN97317.1 - 0.21 10.3 9.0 0.23 10.1 6.3 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 FGF PF00167.13 AIN97318.1 - 0.17 11.6 0.0 0.32 10.7 0.0 1.3 1 0 0 1 1 1 0 Fibroblast growth factor PUF PF00806.14 AIN97319.1 - 7.3e-46 151.1 0.1 6e-06 25.4 0.0 8.6 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat DnaJ PF00226.26 AIN97320.1 - 1.2e-17 63.4 0.3 2.6e-17 62.3 0.2 1.6 1 0 0 1 1 1 1 DnaJ domain EF-hand_7 PF13499.1 AIN97321.1 - 1.1e-11 44.6 2.3 1e-07 31.9 0.3 2.7 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 AIN97321.1 - 5e-09 35.3 1.8 0.00013 21.5 0.0 3.7 4 0 0 4 4 4 2 EF-hand domain EF-hand_1 PF00036.27 AIN97321.1 - 9.9e-09 33.8 1.2 0.00083 18.4 0.1 3.7 3 0 0 3 3 3 2 EF hand EF-hand_8 PF13833.1 AIN97321.1 - 3.2e-05 23.4 1.4 0.41 10.2 0.1 3.2 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.1 AIN97321.1 - 0.0012 18.1 0.5 0.042 13.1 0.1 3.0 3 0 0 3 3 3 1 EF hand DUF3648 PF12364.3 AIN97322.1 - 4.4e-56 188.8 1.6 1.1e-55 187.5 1.1 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3648) PAP_assoc PF03828.14 AIN97322.1 - 0.45 10.4 0.8 1.3 9.0 0.6 1.7 1 0 0 1 1 1 0 Cid1 family poly A polymerase NTP_transf_2 PF01909.18 AIN97322.1 - 0.45 10.8 0.0 1.1 9.5 0.0 1.5 1 0 0 1 1 1 0 Nucleotidyltransferase domain WD40 PF00400.27 AIN97323.1 - 0.00014 21.5 1.2 1.5 8.8 0.1 4.2 4 0 0 4 4 4 2 WD domain, G-beta repeat TFIIA PF03153.8 AIN97323.1 - 0.053 13.4 10.4 0.083 12.7 7.2 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit NADH-G_4Fe-4S_3 PF10588.4 AIN97325.1 - 9e-17 60.0 0.3 9e-17 60.0 0.2 2.0 2 0 0 2 2 2 1 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region Fer2_4 PF13510.1 AIN97325.1 - 3.8e-12 45.8 0.1 1.1e-11 44.4 0.1 1.8 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer2 PF00111.22 AIN97325.1 - 3.9e-07 29.7 0.1 1e-06 28.4 0.1 1.7 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer4_18 PF13746.1 AIN97325.1 - 0.41 11.0 6.5 0.18 12.2 2.3 2.0 2 0 0 2 2 2 0 4Fe-4S dicluster domain Fer4_9 PF13187.1 AIN97325.1 - 2 8.7 6.7 1.3 9.3 2.2 2.4 2 0 0 2 2 2 0 4Fe-4S dicluster domain Fer4_7 PF12838.2 AIN97325.1 - 4.5 7.7 10.6 0.53 10.7 1.9 3.0 3 1 0 3 3 3 0 4Fe-4S dicluster domain zf-C3HC4_3 PF13920.1 AIN97325.1 - 6.7 6.4 9.1 19 5.0 0.0 3.3 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) DnaJ PF00226.26 AIN97326.1 - 4e-13 48.8 0.0 6.5e-13 48.2 0.0 1.3 1 0 0 1 1 1 1 DnaJ domain zf-CSL PF05207.8 AIN97326.1 - 2.3e-05 23.8 4.8 7.8e-05 22.1 3.4 1.9 1 1 0 1 1 1 1 CSL zinc finger Peptidase_S68 PF10461.4 AIN97327.1 - 0.0088 15.7 0.5 0.07 12.8 0.1 2.5 2 0 0 2 2 2 1 Peptidase S68 E1-E2_ATPase PF00122.15 AIN97328.1 - 8.6e-57 191.8 5.9 1.1e-56 191.5 2.4 2.4 3 0 0 3 3 3 1 E1-E2 ATPase Hydrolase PF00702.21 AIN97328.1 - 1.6e-24 87.4 0.0 7.7e-24 85.2 0.0 2.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 AIN97328.1 - 3.1e-13 50.3 0.1 9.3e-13 48.7 0.1 1.9 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 AIN97328.1 - 5.3e-13 48.2 0.0 1.3e-12 47.0 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 AIN97328.1 - 1.9e-05 24.3 0.0 0.00021 20.9 0.1 2.1 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 AIN97328.1 - 0.08 12.8 0.0 0.17 11.8 0.0 1.5 1 0 0 1 1 1 0 Putative hydrolase of sodium-potassium ATPase alpha subunit YrvL PF14184.1 AIN97328.1 - 6.4 6.5 19.9 1.3 8.8 5.7 2.9 3 0 0 3 3 3 0 Regulatory protein YrvL Kinesin PF00225.18 AIN97329.1 - 4.2e-49 167.0 0.0 4.2e-49 167.0 0.0 1.8 2 0 0 2 2 2 1 Kinesin motor domain AAA_22 PF13401.1 AIN97329.1 - 0.025 14.7 1.0 0.075 13.1 0.0 2.4 2 1 0 2 2 2 0 AAA domain RNA_helicase PF00910.17 AIN97329.1 - 0.087 13.0 0.0 0.2 11.8 0.0 1.6 1 0 0 1 1 1 0 RNA helicase DUF87 PF01935.12 AIN97329.1 - 0.4 10.4 3.7 1.5 8.6 0.0 3.1 3 0 0 3 3 3 0 Domain of unknown function DUF87 AAA_23 PF13476.1 AIN97329.1 - 1.3 9.3 9.5 5 7.3 0.0 3.1 3 0 0 3 3 3 0 AAA domain BTB PF00651.26 AIN97330.1 - 6.9e-06 26.0 0.1 1.5e-05 24.9 0.1 1.6 1 0 0 1 1 1 1 BTB/POZ domain zf-C3HC4_3 PF13920.1 AIN97332.1 - 1.6e-14 53.2 13.4 2.1e-14 52.8 9.3 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 AIN97332.1 - 2.8e-07 30.4 17.7 4.2e-07 29.8 12.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 AIN97332.1 - 0.00051 19.8 16.3 0.00076 19.2 11.3 1.3 1 0 0 1 1 1 1 Ring finger domain Prok-RING_4 PF14447.1 AIN97332.1 - 0.075 12.5 9.3 0.14 11.7 6.5 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_4 PF14570.1 AIN97332.1 - 2.5 7.7 11.5 4.7 6.8 8.0 1.4 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain IU_nuc_hydro PF01156.14 AIN97333.1 - 2e-95 319.5 0.2 2.3e-95 319.4 0.1 1.0 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase Kinesin PF00225.18 AIN97335.1 - 1.4e-60 204.8 0.0 2.7e-60 203.8 0.0 1.4 1 0 0 1 1 1 1 Kinesin motor domain Noc2 PF03715.8 AIN97336.1 - 1.7e-97 325.8 0.9 1.7e-97 325.8 0.6 1.5 2 0 0 2 2 2 1 Noc2p family Nop14 PF04147.7 AIN97336.1 - 0.024 12.5 18.8 0.35 8.7 11.7 2.1 2 0 0 2 2 2 0 Nop14-like family Potyvirid-P3 PF13608.1 AIN97336.1 - 0.27 10.2 7.1 0.14 11.2 2.5 2.1 2 0 0 2 2 2 0 Protein P3 of Potyviral polyprotein DUF4441 PF14536.1 AIN97336.1 - 1.8 8.5 5.9 0.49 10.3 1.8 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4441) DUF4375 PF14300.1 AIN97336.1 - 4.7 7.2 7.4 2.3 8.1 2.6 2.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4375) Got1 PF04178.7 AIN97337.1 - 4.7e-16 58.9 16.3 5.3e-16 58.7 11.3 1.0 1 0 0 1 1 1 1 Got1/Sft2-like family ATP1G1_PLM_MAT8 PF02038.11 AIN97337.1 - 0.021 13.8 2.2 0.043 12.8 0.1 2.4 1 1 1 2 2 2 0 ATP1G1/PLM/MAT8 family DUF872 PF05915.7 AIN97337.1 - 2.6 7.9 5.8 0.89 9.4 1.0 2.1 1 1 1 2 2 2 0 Eukaryotic protein of unknown function (DUF872) COPI_assoc PF08507.5 AIN97337.1 - 2.8 7.5 11.0 0.3 10.7 4.3 1.7 2 0 0 2 2 2 0 COPI associated protein DUF1765 PF08578.5 AIN97339.1 - 0.08 12.9 0.1 2.1 8.4 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1765) DUF3812 PF12757.2 AIN97339.1 - 8.4 6.3 15.0 13 5.8 2.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF3812) GCS PF03074.11 AIN97341.1 - 1.9e-162 540.5 0.2 2.4e-162 540.1 0.1 1.1 1 0 0 1 1 1 1 Glutamate-cysteine ligase DUF4332 PF14229.1 AIN97341.1 - 0.19 11.7 0.0 0.44 10.5 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4332) SNARE PF05739.14 AIN97343.1 - 6.9e-10 38.4 2.9 6.9e-10 38.4 2.0 2.8 3 0 0 3 3 3 1 SNARE domain DUF2239 PF09998.4 AIN97343.1 - 0.0066 16.0 1.8 0.0087 15.6 0.2 2.0 2 0 0 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2239) Syntaxin-6_N PF09177.6 AIN97343.1 - 0.026 14.9 0.7 0.026 14.9 0.5 2.7 2 1 0 2 2 2 0 Syntaxin 6, N-terminal IncA PF04156.9 AIN97343.1 - 0.67 9.5 14.9 3.5 7.1 0.3 2.5 2 0 0 2 2 2 0 IncA protein Syntaxin PF00804.20 AIN97343.1 - 1 9.5 21.2 0.12 12.5 1.4 3.4 2 2 1 3 3 3 0 Syntaxin Erp_C PF06780.6 AIN97343.1 - 1.1 9.1 6.8 1.2 9.0 1.5 2.4 2 0 0 2 2 2 0 Erp protein C-terminus Ribosomal_S5_C PF03719.10 AIN97345.1 - 3.1e-24 84.0 0.0 5.2e-24 83.3 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain Ribosomal_S5 PF00333.15 AIN97345.1 - 4.7e-22 77.5 0.8 7.6e-22 76.8 0.5 1.4 1 0 0 1 1 1 1 Ribosomal protein S5, N-terminal domain FoP_duplication PF13865.1 AIN97345.1 - 4.1 7.9 6.0 9 6.8 4.1 1.5 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 SH3_9 PF14604.1 AIN97346.1 - 7.2e-09 35.0 0.0 1.3e-08 34.3 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 AIN97346.1 - 2.6e-07 29.9 0.0 5.1e-07 28.9 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 AIN97346.1 - 3.4e-05 23.2 0.0 8e-05 22.0 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain GlnE PF03710.10 AIN97346.1 - 0.7 9.1 3.2 1.3 8.2 0.0 2.1 2 0 0 2 2 2 0 Glutamate-ammonia ligase adenylyltransferase DnaJ PF00226.26 AIN97347.1 - 1.8e-19 69.2 0.6 1.8e-19 69.2 0.4 2.6 2 0 0 2 2 2 1 DnaJ domain DUF865 PF05906.6 AIN97347.1 - 0.016 14.7 0.4 0.03 13.8 0.3 1.4 1 0 0 1 1 1 0 Herpesvirus-7 repeat of unknown function (DUF865) DnaJ PF00226.26 AIN97348.1 - 0.21 11.3 3.7 3.3 7.5 0.4 2.9 2 1 0 2 2 2 0 DnaJ domain Fibrillarin PF01269.12 AIN97349.1 - 5.8e-102 339.4 0.0 6.6e-102 339.2 0.0 1.0 1 0 0 1 1 1 1 Fibrillarin GCD14 PF08704.5 AIN97349.1 - 8.5e-07 28.7 0.0 1.2e-06 28.2 0.0 1.1 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit Clathrin_lg_ch PF01086.12 AIN97350.1 - 2.7e-10 40.5 0.0 2.9e-10 40.4 0.0 1.0 1 0 0 1 1 1 1 Clathrin light chain Globin PF00042.17 AIN97350.1 - 0.07 13.4 0.7 0.11 12.8 0.5 1.2 1 0 0 1 1 1 0 Globin FlgM PF04316.8 AIN97350.1 - 0.094 12.6 0.2 0.094 12.6 0.1 2.2 1 1 1 2 2 2 0 Anti-sigma-28 factor, FlgM ZYG-11_interact PF05884.7 AIN97350.1 - 0.27 10.2 1.5 0.32 10.0 1.0 1.1 1 0 0 1 1 1 0 Interactor of ZYG-11 DUF4557 PF15101.1 AIN97350.1 - 0.56 10.0 3.5 0.73 9.6 2.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) CDC27 PF09507.5 AIN97350.1 - 0.86 8.7 11.9 0.92 8.6 8.2 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Ribosomal_L30_N PF08079.7 AIN97350.1 - 2.9 7.9 10.0 5.7 7.0 6.9 1.5 1 0 0 1 1 1 0 Ribosomal L30 N-terminal domain SNARE PF05739.14 AIN97351.1 - 2.7e-09 36.5 6.7 5.4e-09 35.6 3.5 2.2 2 0 0 2 2 2 1 SNARE domain Laminin_II PF06009.7 AIN97351.1 - 0.012 15.3 4.0 0.39 10.4 0.4 3.0 2 1 1 3 3 3 0 Laminin Domain II Methyltransf_3 PF01596.12 AIN97351.1 - 0.037 13.0 0.0 0.055 12.5 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase Baculo_11_kDa PF06143.6 AIN97351.1 - 0.1 12.0 0.4 0.26 10.6 0.3 1.7 1 0 0 1 1 1 0 Baculovirus 11 kDa family COG5 PF10392.4 AIN97351.1 - 0.29 11.0 4.2 1.2 9.1 0.9 2.4 1 1 1 2 2 2 0 Golgi transport complex subunit 5 Spectrin PF00435.16 AIN97351.1 - 4.3 7.6 10.0 21 5.4 1.9 3.1 2 1 2 4 4 4 0 Spectrin repeat DER1 PF04511.10 AIN97352.1 - 8e-31 107.0 6.6 9.1e-31 106.8 4.6 1.0 1 0 0 1 1 1 1 Der1-like family DUF2306 PF10067.4 AIN97352.1 - 0.15 12.2 2.7 0.39 10.8 1.8 1.8 1 1 0 1 1 1 0 Predicted membrane protein (DUF2306) Pkinase PF00069.20 AIN97353.1 - 1.6e-53 181.5 0.0 2.7e-53 180.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AIN97353.1 - 1e-24 87.0 0.0 2.9e-20 72.4 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase CAP_GLY PF01302.20 AIN97353.1 - 9.3e-17 60.5 0.7 1.7e-16 59.6 0.5 1.5 1 0 0 1 1 1 1 CAP-Gly domain Kinase-like PF14531.1 AIN97353.1 - 7.3e-06 25.1 0.0 0.0059 15.6 0.0 2.2 2 0 0 2 2 2 2 Kinase-like Pkinase PF00069.20 AIN97354.1 - 7.4e-57 192.4 0.0 8.3e-57 192.2 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AIN97354.1 - 2.5e-34 118.5 0.0 3e-34 118.2 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase ABC1 PF03109.11 AIN97354.1 - 0.013 15.4 0.0 0.03 14.2 0.0 1.6 1 0 0 1 1 1 0 ABC1 family Peptidase_M24 PF00557.19 AIN97355.1 - 5e-28 98.0 0.7 6.5e-28 97.7 0.5 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 Pkinase PF00069.20 AIN97357.1 - 8.3e-71 238.1 0.0 1e-70 237.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AIN97357.1 - 8.8e-31 106.9 0.1 3.5e-30 104.9 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 AIN97357.1 - 0.023 14.4 0.0 0.036 13.8 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family HTH_3 PF01381.17 AIN97358.1 - 1.4e-11 44.0 0.2 2.2e-11 43.4 0.1 1.3 1 0 0 1 1 1 1 Helix-turn-helix MBF1 PF08523.5 AIN97358.1 - 2.3e-05 24.3 3.8 2.3e-05 24.3 2.6 1.7 2 0 0 2 2 2 1 Multiprotein bridging factor 1 HTH_31 PF13560.1 AIN97358.1 - 0.00045 20.3 0.4 0.00085 19.4 0.3 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_19 PF12844.2 AIN97358.1 - 0.00054 19.9 0.1 0.00082 19.3 0.1 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain DUF2152 PF10222.4 AIN97358.1 - 0.062 11.5 0.4 0.073 11.2 0.3 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2152) Spectrin PF00435.16 AIN97358.1 - 0.39 11.0 4.4 0.61 10.4 3.1 1.3 1 0 0 1 1 1 0 Spectrin repeat Mito_carr PF00153.22 AIN97359.1 - 3.6e-68 225.3 3.0 2.2e-23 81.7 0.0 3.0 2 1 1 3 3 3 3 Mitochondrial carrier protein Mito_carr PF00153.22 AIN97360.1 - 3.5e-68 225.3 3.1 2.2e-23 81.7 0.0 3.0 2 1 1 3 3 3 3 Mitochondrial carrier protein polyprenyl_synt PF00348.12 AIN97361.1 - 1.1e-36 126.0 0.0 1.5e-36 125.5 0.0 1.2 1 0 0 1 1 1 1 Polyprenyl synthetase CrtC PF07143.6 AIN97361.1 - 7.2e-27 94.5 0.0 5.5e-25 88.3 0.0 2.1 2 0 0 2 2 2 2 Hydroxyneurosporene synthase (CrtC) CDK5_activator PF03261.10 AIN97361.1 - 0.17 11.1 0.0 0.27 10.5 0.0 1.2 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein Complex1_LYR PF05347.10 AIN97362.1 - 2.5e-07 30.4 0.2 2.9e-06 26.9 0.0 2.8 2 0 0 2 2 2 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 AIN97362.1 - 4.1e-05 23.7 0.1 0.00048 20.2 0.0 2.8 2 1 0 2 2 2 1 Complex1_LYR-like GN3L_Grn1 PF08701.6 AIN97363.1 - 0.00051 19.8 13.3 0.0013 18.6 9.2 1.7 1 0 0 1 1 1 1 GNL3L/Grn1 putative GTPase UVR PF02151.14 AIN97364.1 - 2e-08 33.4 15.1 0.00037 19.9 4.9 2.6 2 0 0 2 2 2 2 UvrB/uvrC motif zf-Di19 PF05605.7 AIN97364.1 - 0.012 15.7 3.0 0.012 15.7 2.1 2.9 2 1 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding HEAT PF02985.17 AIN97364.1 - 0.057 13.5 0.3 3.7 7.8 0.0 3.5 3 0 0 3 3 3 0 HEAT repeat HEAT_EZ PF13513.1 AIN97364.1 - 0.84 10.2 7.2 2.9 8.5 0.6 3.5 3 0 0 3 3 3 0 HEAT-like repeat zf-H2C2_5 PF13909.1 AIN97364.1 - 1.9 8.8 8.8 15 6.0 1.1 2.9 2 0 0 2 2 2 0 C2H2-type zinc-finger domain Kinesin PF00225.18 AIN97365.1 - 1.9e-102 342.4 0.5 5.3e-102 340.9 0.0 1.9 2 0 0 2 2 2 1 Kinesin motor domain VHS PF00790.14 AIN97365.1 - 2.4e-05 23.9 0.1 0.0001 21.9 0.0 2.2 2 0 0 2 2 2 1 VHS domain Dor1 PF04124.7 AIN97365.1 - 0.00014 20.4 0.6 0.00026 19.5 0.4 1.4 1 0 0 1 1 1 1 Dor1-like family TPR_MLP1_2 PF07926.7 AIN97365.1 - 0.22 11.2 12.7 2.1 8.0 5.1 2.7 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein DUF87 PF01935.12 AIN97365.1 - 3.9 7.2 7.9 23 4.7 0.1 3.6 3 0 0 3 3 3 0 Domain of unknown function DUF87 Tup_N PF08581.5 AIN97365.1 - 7.6 6.8 16.1 1.9 8.7 4.3 3.3 2 1 1 3 3 3 0 Tup N-terminal Dynamin_N PF00350.18 AIN97367.1 - 1.4e-18 67.3 0.0 3.5e-17 62.7 0.0 2.4 1 1 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.18 AIN97367.1 - 1.2e-07 31.6 0.0 3.8e-07 30.0 0.0 1.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_22 PF13401.1 AIN97367.1 - 0.037 14.1 0.1 2.5 8.2 0.0 3.0 4 0 0 4 4 4 0 AAA domain cobW PF02492.14 AIN97367.1 - 0.11 11.8 0.0 6.3 6.1 0.0 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain U-box PF04564.10 AIN97369.1 - 0.0027 17.6 0.0 0.0066 16.3 0.0 1.7 1 0 0 1 1 1 1 U-box domain UCR_hinge PF02320.11 AIN97369.1 - 0.025 14.5 3.4 0.073 13.0 2.3 1.8 1 0 0 1 1 1 0 Ubiquinol-cytochrome C reductase hinge protein zf-CCCH PF00642.19 AIN97370.1 - 0.00036 20.1 6.2 0.0019 17.8 0.7 2.4 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) U-box PF04564.10 AIN97370.1 - 0.0053 16.6 0.0 0.012 15.5 0.0 1.5 1 0 0 1 1 1 1 U-box domain CorA PF01544.13 AIN97370.1 - 0.12 11.3 3.1 0.18 10.8 2.2 1.1 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein Cep57_CLD_2 PF14197.1 AIN97370.1 - 0.41 10.6 4.2 1.9 8.4 2.9 2.0 1 1 0 1 1 1 0 Centrosome localisation domain of PPC89 UPF0016 PF01169.14 AIN97371.1 - 2.2e-43 146.2 21.0 6.7e-23 80.6 3.2 2.2 2 0 0 2 2 2 2 Uncharacterized protein family UPF0016 Abhydrolase_9_N PF15420.1 AIN97371.1 - 0.0021 17.8 2.6 0.0023 17.7 0.2 2.0 1 1 1 2 2 2 1 Alpha/beta-hydrolase family N-terminus DUF4064 PF13273.1 AIN97371.1 - 3.4 7.8 9.0 0.39 10.8 0.8 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF4064) ABC_transp_aux PF09822.4 AIN97372.1 - 3.3e-07 30.0 0.0 5.7e-07 29.2 0.0 1.3 1 0 0 1 1 1 1 ABC-type uncharacterized transport system DUF1355 PF07090.6 AIN97372.1 - 0.15 11.4 0.0 0.27 10.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1355) WD40 PF00400.27 AIN97373.1 - 4.8e-11 42.1 1.2 7.2e-06 25.6 0.1 3.7 4 0 0 4 4 4 2 WD domain, G-beta repeat Coatomer_WDAD PF04053.9 AIN97373.1 - 0.00086 18.2 0.0 0.0058 15.4 0.0 2.3 3 0 0 3 3 3 1 Coatomer WD associated region DUF1143 PF06608.6 AIN97374.1 - 0.0088 16.0 2.3 0.3 11.0 0.7 2.5 2 1 0 2 2 2 1 Protein of unknown function (DUF1143) EF-hand_7 PF13499.1 AIN97374.1 - 0.14 12.2 0.0 0.81 9.8 0.0 2.3 2 1 0 2 2 2 0 EF-hand domain pair Radical_SAM PF04055.16 AIN97375.1 - 1.7e-10 41.3 0.1 2.5e-10 40.7 0.1 1.3 1 0 0 1 1 1 1 Radical SAM superfamily Pkinase PF00069.20 AIN97376.1 - 6.2e-31 107.4 0.2 1.9e-17 63.2 0.0 3.8 3 1 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.12 AIN97376.1 - 1.6e-08 33.9 0.1 0.002 17.2 0.0 2.7 3 0 0 3 3 3 2 Protein tyrosine kinase RIO1 PF01163.17 AIN97376.1 - 0.018 14.3 0.1 0.046 13.0 0.0 1.6 1 0 0 1 1 1 0 RIO1 family WD40 PF00400.27 AIN97378.1 - 3.3e-16 58.4 0.9 0.00015 21.5 0.1 5.4 4 0 0 4 4 4 4 WD domain, G-beta repeat PDZ_2 PF13180.1 AIN97378.1 - 5.2e-06 26.2 0.0 1.3e-05 25.0 0.0 1.7 1 0 0 1 1 1 1 PDZ domain Ribosomal_S13_N PF08069.7 AIN97379.1 - 6.7e-25 86.7 2.0 6.7e-25 86.7 1.4 1.7 2 0 0 2 2 2 1 Ribosomal S13/S15 N-terminal domain Ribosomal_S15 PF00312.17 AIN97379.1 - 9.4e-22 76.5 0.4 1.4e-21 75.9 0.3 1.3 1 0 0 1 1 1 1 Ribosomal protein S15 Synaptobrevin PF00957.16 AIN97380.1 - 2.4e-11 43.0 0.0 4.6e-11 42.1 0.0 1.5 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.1 AIN97380.1 - 0.018 14.5 0.0 0.12 11.9 0.0 2.1 2 0 0 2 2 2 0 Regulated-SNARE-like domain UMP1 PF05348.6 AIN97381.1 - 4.9e-07 29.7 0.0 6.8e-07 29.2 0.0 1.1 1 0 0 1 1 1 1 Proteasome maturation factor UMP1 TFIIS_C PF01096.13 AIN97382.1 - 2.8e-18 65.2 2.4 2.8e-18 65.2 1.6 2.3 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.11 AIN97382.1 - 0.00011 21.8 1.7 0.0012 18.4 0.2 2.4 2 0 0 2 2 2 1 RNA polymerases M/15 Kd subunit Zn_Tnp_IS1595 PF12760.2 AIN97382.1 - 0.0029 17.3 1.4 1.3 8.8 0.1 2.6 2 0 0 2 2 2 2 Transposase zinc-ribbon domain Baculo_LEF5_C PF11792.3 AIN97382.1 - 0.041 13.2 0.2 0.041 13.2 0.1 2.3 3 0 0 3 3 3 0 Baculoviridae late expression factor 5 C-terminal domain DUF2387 PF09526.5 AIN97382.1 - 0.097 12.6 2.9 1.6 8.7 0.2 2.8 3 0 0 3 3 3 0 Probable metal-binding protein (DUF2387) DZR PF12773.2 AIN97382.1 - 2.1 8.2 5.3 4.9 7.0 0.1 2.7 3 0 0 3 3 3 0 Double zinc ribbon PhnA_Zn_Ribbon PF08274.7 AIN97382.1 - 2.1 8.1 5.3 6.1 6.7 0.1 2.9 2 1 1 3 3 3 0 PhnA Zinc-Ribbon NAP PF00956.13 AIN97384.1 - 5.9e-61 205.6 0.3 5.9e-61 205.6 0.2 2.0 2 0 0 2 2 2 1 Nucleosome assembly protein (NAP) BSP_II PF05432.6 AIN97384.1 - 0.00053 19.3 4.5 0.00053 19.3 3.1 2.1 2 0 0 2 2 2 1 Bone sialoprotein II (BSP-II) MgtE_N PF03448.12 AIN97384.1 - 0.0011 19.2 0.4 0.003 17.8 0.3 1.7 1 0 0 1 1 1 1 MgtE intracellular N domain Daxx PF03344.10 AIN97384.1 - 0.059 11.8 4.4 0.1 11.0 3.0 1.4 1 0 0 1 1 1 0 Daxx Family Nucleoplasmin PF03066.10 AIN97384.1 - 4.4 6.8 18.5 2.6 7.5 0.1 2.7 3 0 0 3 3 3 0 Nucleoplasmin Uso1_p115_C PF04871.8 AIN97385.1 - 0.0053 16.7 1.4 0.009 15.9 0.9 1.3 1 0 0 1 1 1 1 Uso1 / p115 like vesicle tethering protein, C terminal region DUF2360 PF10152.4 AIN97386.1 - 7.4e-54 182.0 0.0 1.6e-53 180.9 0.0 1.6 1 1 0 1 1 1 1 Predicted coiled-coil domain-containing protein (DUF2360) DUF952 PF06108.7 AIN97387.1 - 0.058 13.2 0.1 0.44 10.4 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF952) Strabismus PF06638.6 AIN97388.1 - 0.15 10.3 2.7 0.21 9.8 1.9 1.1 1 0 0 1 1 1 0 Strabismus protein PepX_C PF08530.5 AIN97390.1 - 0.068 13.0 0.2 0.092 12.6 0.1 1.2 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain SAP PF02037.22 AIN97391.1 - 0.074 12.5 0.0 0.41 10.2 0.0 2.3 2 0 0 2 2 2 0 SAP domain LRR_4 PF12799.2 AIN97393.1 - 2.1e-09 36.7 0.0 0.006 16.1 0.0 3.5 1 1 2 3 3 3 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 AIN97393.1 - 2e-06 27.4 0.3 0.0084 15.8 0.0 2.5 2 0 0 2 2 2 2 Leucine rich repeat LRR_1 PF00560.28 AIN97393.1 - 0.14 12.2 1.4 1e+02 3.5 0.0 4.3 4 1 0 4 4 4 0 Leucine Rich Repeat Peptidase_M24 PF00557.19 AIN97394.1 - 7.9e-44 149.7 0.1 1e-43 149.3 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 zf-MYND PF01753.13 AIN97394.1 - 5.7e-05 22.9 5.8 0.00013 21.8 4.0 1.6 1 0 0 1 1 1 1 MYND finger IR1-M PF12185.3 AIN97394.1 - 0.23 11.2 1.4 0.57 9.9 1.0 1.6 1 0 0 1 1 1 0 Nup358/RanBP2 E3 ligase domain DUF1042 PF06294.6 AIN97395.1 - 6.8e-08 32.2 0.0 1.2e-07 31.5 0.0 1.3 1 0 0 1 1 1 1 Domain of Unknown Function (DUF1042) TBCC PF07986.7 AIN97397.1 - 9.3e-24 83.1 13.8 5.2e-09 35.5 0.0 3.4 3 0 0 3 3 3 3 Tubulin binding cofactor C Pkinase PF00069.20 AIN97397.1 - 0.13 11.4 0.0 3.2 6.8 0.0 2.3 2 0 0 2 2 2 0 Protein kinase domain Phage-A118_gp45 PF10653.4 AIN97397.1 - 0.5 10.2 0.0 2 8.3 0.0 1.9 2 0 0 2 2 2 0 Protein gp45 of Bacteriophage A118 Pkinase PF00069.20 AIN97398.1 - 9.5e-42 142.9 0.0 1.5e-31 109.5 0.0 3.2 3 0 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.12 AIN97398.1 - 9.6e-15 54.3 0.0 1.1e-13 50.8 0.0 2.2 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 AIN97398.1 - 0.07 12.0 0.0 1.1 8.1 0.0 2.1 2 0 0 2 2 2 0 Kinase-like Cep57_CLD_2 PF14197.1 AIN97399.1 - 0.076 12.9 1.7 0.13 12.2 1.2 1.3 1 0 0 1 1 1 0 Centrosome localisation domain of PPC89 DAG1 PF05454.6 AIN97400.1 - 3.6e-05 23.0 1.0 3.9e-05 22.9 0.7 1.1 1 0 0 1 1 1 1 Dystroglycan (Dystrophin-associated glycoprotein 1) Mid2 PF04478.7 AIN97400.1 - 0.077 12.4 0.5 0.092 12.1 0.3 1.1 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor MscL PF01741.13 AIN97400.1 - 0.35 11.0 2.2 0.78 9.8 1.5 1.5 1 1 0 1 1 1 0 Large-conductance mechanosensitive channel, MscL DUF2749 PF10907.3 AIN97400.1 - 2.8 7.8 4.2 14 5.5 0.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2749) CYTH PF01928.16 AIN97401.1 - 2.2e-13 50.2 0.2 3.4e-05 23.6 0.0 3.8 4 0 0 4 4 4 2 CYTH domain Histone PF00125.19 AIN97402.1 - 8e-25 86.7 0.8 1.7e-24 85.6 0.6 1.6 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 AIN97402.1 - 1.9e-07 31.0 1.3 5.2e-07 29.6 0.0 2.0 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-T PF15511.1 AIN97402.1 - 0.0016 17.7 1.0 0.002 17.4 0.7 1.1 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T ANF_receptor PF01094.23 AIN97403.1 - 1.4e-31 109.6 7.5 1.9e-24 86.1 1.6 3.2 3 0 0 3 3 3 3 Receptor family ligand binding region Peripla_BP_6 PF13458.1 AIN97403.1 - 6.4e-14 52.0 4.6 2.7e-10 40.1 1.1 2.5 2 1 0 2 2 2 2 Periplasmic binding protein Surp PF01805.15 AIN97404.1 - 0.0013 18.3 0.0 0.0013 18.3 0.0 1.6 2 0 0 2 2 2 1 Surp module Lysyl_oxidase PF01186.12 AIN97404.1 - 0.059 12.9 0.0 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 Lysyl oxidase Methyltransf_23 PF13489.1 AIN97404.1 - 0.11 12.1 0.0 0.25 11.0 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain RNA_pol_A_bac PF01000.21 AIN97405.1 - 9.7e-20 70.8 0.0 2e-19 69.8 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.19 AIN97405.1 - 4.9e-11 41.5 0.0 6.8e-11 41.1 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Fer4_7 PF12838.2 AIN97405.1 - 0.015 15.6 2.3 0.046 14.1 1.6 1.9 1 1 0 1 1 1 0 4Fe-4S dicluster domain Fer4_11 PF13247.1 AIN97405.1 - 0.067 13.0 1.5 0.15 12.0 1.1 1.6 1 0 0 1 1 1 0 4Fe-4S dicluster domain Fer4_9 PF13187.1 AIN97405.1 - 0.098 12.9 0.4 0.098 12.9 0.3 1.8 2 0 0 2 2 2 0 4Fe-4S dicluster domain Utp11 PF03998.8 AIN97406.1 - 6.6e-52 176.7 21.9 6.6e-52 176.7 15.2 2.0 1 1 0 2 2 2 2 Utp11 protein Kinesin PF00225.18 AIN97407.1 - 8.3e-91 304.1 0.0 5.7e-90 301.4 0.0 2.4 2 0 0 2 2 2 1 Kinesin motor domain FliJ PF02050.11 AIN97407.1 - 0.014 15.4 1.3 0.014 15.4 0.9 6.6 4 1 4 8 8 8 0 Flagellar FliJ protein DUF1213 PF06740.7 AIN97408.1 - 5.5 7.1 8.9 22 5.2 4.1 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF1213) SlyX PF04102.7 AIN97409.1 - 0.13 12.6 0.3 0.13 12.6 0.2 8.4 4 3 3 7 7 7 0 SlyX SAP PF02037.22 AIN97409.1 - 0.16 11.5 0.2 0.16 11.5 0.1 3.7 4 0 0 4 4 4 0 SAP domain Kinesin PF00225.18 AIN97410.1 - 2e-93 312.7 9.1 1.5e-76 257.2 0.2 4.7 4 0 0 4 4 4 3 Kinesin motor domain MtrG PF04210.8 AIN97410.1 - 3.2 7.4 5.2 1.8 8.2 0.6 2.7 2 0 0 2 2 2 0 Tetrahydromethanopterin S-methyltransferase, subunit G Ldh_1_N PF00056.18 AIN97411.1 - 1.2e-35 122.3 0.3 2e-35 121.6 0.2 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.13 AIN97411.1 - 1.4e-31 109.5 0.0 2e-31 109.0 0.0 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain 3Beta_HSD PF01073.14 AIN97411.1 - 0.0081 14.9 0.0 0.08 11.6 0.0 2.0 1 1 1 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Baculo_PEP_C PF04513.7 AIN97412.1 - 1.6e-05 24.7 10.9 0.12 12.1 0.7 3.5 1 1 2 3 3 3 2 Baculovirus polyhedron envelope protein, PEP, C terminus DUF1664 PF07889.7 AIN97412.1 - 0.00031 20.5 9.5 0.005 16.6 1.6 2.9 2 2 0 2 2 2 1 Protein of unknown function (DUF1664) TPR_MLP1_2 PF07926.7 AIN97412.1 - 0.00035 20.3 0.7 0.00035 20.3 0.5 3.4 2 1 0 3 3 3 1 TPR/MLP1/MLP2-like protein GAS PF13851.1 AIN97412.1 - 0.00073 18.7 3.2 0.00073 18.7 2.2 2.8 1 1 1 2 2 2 1 Growth-arrest specific micro-tubule binding Reo_sigmaC PF04582.7 AIN97412.1 - 0.00087 18.5 5.9 0.19 10.8 0.2 2.3 1 1 1 2 2 2 2 Reovirus sigma C capsid protein DUF948 PF06103.6 AIN97412.1 - 0.0013 18.5 2.2 1.7 8.5 0.0 4.0 1 1 3 4 4 4 1 Bacterial protein of unknown function (DUF948) Laminin_II PF06009.7 AIN97412.1 - 0.0036 17.0 11.8 0.017 14.8 0.2 3.7 2 1 2 4 4 4 1 Laminin Domain II RmuC PF02646.11 AIN97412.1 - 0.005 15.7 10.9 0.035 12.9 0.3 3.3 1 1 2 3 3 3 1 RmuC family TMF_TATA_bd PF12325.3 AIN97412.1 - 0.0051 16.5 7.1 0.0051 16.5 4.9 3.4 2 2 1 3 3 3 1 TATA element modulatory factor 1 TATA binding Syntaxin_2 PF14523.1 AIN97412.1 - 0.0058 16.6 7.2 0.67 10.0 0.0 3.4 2 1 1 3 3 2 1 Syntaxin-like protein LXG PF04740.7 AIN97412.1 - 0.0091 15.8 0.5 0.0091 15.8 0.3 3.0 2 1 1 3 3 3 1 LXG domain of WXG superfamily Fib_alpha PF08702.5 AIN97412.1 - 0.012 15.7 6.8 0.29 11.2 0.1 3.1 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family AAA_13 PF13166.1 AIN97412.1 - 0.016 13.7 5.3 0.025 13.0 2.9 1.7 1 1 0 1 1 1 0 AAA domain Spc7 PF08317.6 AIN97412.1 - 0.026 13.1 13.5 0.43 9.1 4.1 2.3 1 1 1 2 2 2 0 Spc7 kinetochore protein BLOC1_2 PF10046.4 AIN97412.1 - 0.026 14.6 9.1 10 6.3 0.6 4.3 1 1 4 5 5 5 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF552 PF04472.7 AIN97412.1 - 0.03 14.2 0.8 0.28 11.1 0.0 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF552) TMCO5 PF14992.1 AIN97412.1 - 0.03 13.4 6.9 0.38 9.8 3.6 2.2 2 0 0 2 2 2 0 TMCO5 family PXA PF02194.10 AIN97412.1 - 0.032 13.8 3.2 0.079 12.5 2.2 1.6 1 0 0 1 1 1 0 PXA domain DUF4200 PF13863.1 AIN97412.1 - 0.046 13.6 14.1 6.9 6.6 5.7 4.2 2 1 2 4 4 4 0 Domain of unknown function (DUF4200) AF0941-like PF14591.1 AIN97412.1 - 0.047 13.7 6.4 0.25 11.3 1.9 3.6 2 1 0 2 2 2 0 AF0941-like LOH1CR12 PF10158.4 AIN97412.1 - 0.053 13.3 4.4 1.6 8.4 0.0 3.2 1 1 3 4 4 4 0 Tumour suppressor protein DUF2730 PF10805.3 AIN97412.1 - 0.054 13.2 2.7 0.18 11.5 0.0 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF2730) Prefoldin_2 PF01920.15 AIN97412.1 - 0.07 12.8 10.7 0.43 10.3 0.8 4.0 3 2 1 4 4 4 0 Prefoldin subunit HsbA PF12296.3 AIN97412.1 - 0.079 12.8 0.6 11 5.9 0.0 3.2 2 2 1 3 3 2 0 Hydrophobic surface binding protein A ApoLp-III PF07464.6 AIN97412.1 - 0.083 12.9 8.0 0.054 13.5 3.0 2.4 2 1 0 2 2 2 0 Apolipophorin-III precursor (apoLp-III) DUF2721 PF11026.3 AIN97412.1 - 0.084 12.5 0.1 0.084 12.5 0.0 3.7 2 1 2 4 4 4 0 Protein of unknown function (DUF2721) CagA PF03507.8 AIN97412.1 - 0.088 12.6 4.3 0.2 11.5 2.8 1.8 1 1 0 1 1 1 0 CagA exotoxin FadA PF09403.5 AIN97412.1 - 0.093 12.7 7.3 0.21 11.6 1.6 2.8 2 1 1 3 3 3 0 Adhesion protein FadA Z1 PF10593.4 AIN97412.1 - 0.098 11.8 1.2 0.28 10.3 0.3 1.9 2 0 0 2 2 2 0 Z1 domain IFT57 PF10498.4 AIN97412.1 - 0.1 11.3 10.0 0.078 11.7 3.4 2.2 1 1 1 2 2 2 0 Intra-flagellar transport protein 57 Bacillus_HBL PF05791.6 AIN97412.1 - 0.12 11.7 6.5 1.5 8.1 1.1 3.1 1 1 1 3 3 3 0 Bacillus haemolytic enterotoxin (HBL) DUF972 PF06156.8 AIN97412.1 - 0.13 12.5 10.1 3.6 7.9 0.1 3.4 2 2 0 2 2 2 0 Protein of unknown function (DUF972) DASH_Dad3 PF08656.5 AIN97412.1 - 0.16 11.6 3.6 6.6 6.5 0.0 3.4 2 1 0 2 2 2 0 DASH complex subunit Dad3 MitMem_reg PF13012.1 AIN97412.1 - 0.18 11.9 4.3 12 6.0 0.1 3.2 2 1 1 3 3 3 0 Maintenance of mitochondrial structure and function COG2 PF06148.6 AIN97412.1 - 0.23 11.3 14.2 4.4 7.1 0.1 4.1 1 1 2 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 Tropomyosin_1 PF12718.2 AIN97412.1 - 0.26 11.1 16.5 3.4 7.4 8.4 3.2 1 1 1 2 2 2 0 Tropomyosin like AcylCoA_dehyd_C PF12186.3 AIN97412.1 - 0.27 11.1 5.4 4.8 7.0 0.2 3.3 2 1 1 3 3 3 0 Acyl-CoA dehydrogenase C terminal IncA PF04156.9 AIN97412.1 - 0.31 10.6 18.7 9 5.8 0.8 3.1 1 1 1 2 2 2 0 IncA protein Syntaxin PF00804.20 AIN97412.1 - 0.34 11.0 14.5 17 5.6 5.7 3.9 2 1 1 3 3 3 0 Syntaxin TMP_2 PF06791.8 AIN97412.1 - 0.44 10.1 4.5 0.18 11.3 0.7 2.1 2 1 0 2 2 2 0 Prophage tail length tape measure protein V_ATPase_I PF01496.14 AIN97412.1 - 0.47 8.2 9.4 0.6 7.9 4.8 2.3 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family Snapin_Pallidin PF14712.1 AIN97412.1 - 0.63 10.3 11.5 1.3 9.4 0.2 3.6 2 1 2 4 4 4 0 Snapin/Pallidin Lectin_N PF03954.9 AIN97412.1 - 0.69 9.3 9.4 8.6 5.7 0.3 3.5 2 1 1 3 3 3 0 Hepatic lectin, N-terminal domain K-box PF01486.12 AIN97412.1 - 0.83 9.4 12.0 0.18 11.6 4.0 2.9 2 1 1 3 3 3 0 K-box region FliD_C PF07195.7 AIN97412.1 - 1.2 8.3 7.2 1.4 8.1 2.0 2.3 2 1 0 2 2 2 0 Flagellar hook-associated protein 2 C-terminus DUF4239 PF14023.1 AIN97412.1 - 1.3 8.3 7.9 2.5 7.4 1.8 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF4239) DUF479 PF04336.7 AIN97412.1 - 1.4 9.0 5.6 5.7 7.1 0.2 3.8 2 1 1 4 4 4 0 Protein of unknown function, DUF479 CENP-H PF05837.7 AIN97412.1 - 1.6 8.9 11.8 1 9.5 2.8 3.0 2 2 1 3 3 2 0 Centromere protein H (CENP-H) MAP7 PF05672.6 AIN97412.1 - 2.2 7.6 18.5 1.6 8.1 11.1 2.1 1 1 0 1 1 1 0 MAP7 (E-MAP-115) family ALIX_LYPXL_bnd PF13949.1 AIN97412.1 - 2.3 7.0 21.3 0.25 10.2 7.4 2.9 1 1 2 3 3 3 0 ALIX V-shaped domain binding to HIV YtxH PF12732.2 AIN97412.1 - 2.9 8.3 7.5 5.4e+02 1.0 5.2 3.9 1 1 0 1 1 1 0 YtxH-like protein WXG100 PF06013.7 AIN97412.1 - 3.1 7.8 19.3 4.9 7.2 0.3 5.7 1 1 5 6 6 6 0 Proteins of 100 residues with WXG Pex19 PF04614.7 AIN97412.1 - 3.6 7.1 9.4 96 2.4 6.5 2.2 1 1 0 1 1 1 0 Pex19 protein family Tropomyosin PF00261.15 AIN97412.1 - 5 6.1 20.4 1.8 7.5 11.3 2.1 1 1 1 2 2 2 0 Tropomyosin Seryl_tRNA_N PF02403.17 AIN97412.1 - 5.1 7.1 15.5 44 4.1 4.6 3.8 2 1 2 4 4 4 0 Seryl-tRNA synthetase N-terminal domain APG6 PF04111.7 AIN97412.1 - 6 5.8 14.3 2.6 6.9 6.7 2.4 1 1 2 3 3 3 0 Autophagy protein Apg6 Phage_GPO PF05929.6 AIN97412.1 - 6.2 5.9 18.2 7.3 5.7 1.1 3.3 1 1 3 4 4 4 0 Phage capsid scaffolding protein (GPO) serine peptidase TMPIT PF07851.8 AIN97412.1 - 9 5.2 6.8 7.7 5.4 0.7 2.7 1 1 2 3 3 3 0 TMPIT-like protein Methyltransf_11 PF08241.7 AIN97413.1 - 3.7e-11 43.3 0.0 9.2e-11 42.0 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 AIN97413.1 - 1.2e-10 41.7 0.0 2.3e-10 40.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 AIN97413.1 - 6.7e-10 38.9 0.0 1.4e-09 37.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 AIN97413.1 - 3.9e-07 29.7 0.0 7.1e-07 28.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 AIN97413.1 - 2.1e-06 27.9 0.0 4.7e-06 26.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.10 AIN97413.1 - 0.0011 18.7 0.0 0.0019 17.8 0.0 1.4 1 0 0 1 1 1 1 Hypothetical methyltransferase Ubie_methyltran PF01209.13 AIN97413.1 - 0.0011 18.0 0.0 0.0017 17.4 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_18 PF12847.2 AIN97413.1 - 0.003 18.0 0.0 0.0073 16.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain EAP30 PF04157.11 AIN97414.1 - 1.5e-39 135.4 0.0 2e-39 135.0 0.0 1.2 1 0 0 1 1 1 1 EAP30/Vps36 family Vps36_ESCRT-II PF11605.3 AIN97414.1 - 3.6e-23 81.1 0.0 6.6e-23 80.3 0.0 1.5 1 0 0 1 1 1 1 Vacuolar protein sorting protein 36 Vps36 PhnJ PF06007.6 AIN97414.1 - 0.0064 15.3 0.0 0.0099 14.6 0.0 1.2 1 0 0 1 1 1 1 Phosphonate metabolism protein PhnJ IRS PF02174.12 AIN97414.1 - 0.066 12.8 0.0 0.14 11.7 0.0 1.5 1 0 0 1 1 1 0 PTB domain (IRS-1 type) Med3 PF11593.3 AIN97414.1 - 8.3 5.5 6.9 12 5.0 4.8 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Rsm22 PF09243.5 AIN97415.1 - 0.0065 15.5 0.0 0.012 14.6 0.0 1.4 1 0 0 1 1 1 1 Mitochondrial small ribosomal subunit Rsm22 Mem_trans PF03547.13 AIN97416.1 - 5.8e-26 90.6 2.9 3.8e-25 88.0 2.0 2.0 1 1 0 1 1 1 1 Membrane transport protein V-SNARE_C PF12352.3 AIN97417.1 - 9.7e-11 41.5 3.4 9.7e-11 41.5 2.4 2.7 3 0 0 3 3 3 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.8 AIN97417.1 - 2.3e-06 27.2 0.7 8.8e-06 25.3 0.0 2.2 3 0 0 3 3 3 1 Sec20 IncA PF04156.9 AIN97417.1 - 0.0058 16.2 3.4 0.0058 16.2 2.4 1.9 3 0 0 3 3 3 1 IncA protein Fib_alpha PF08702.5 AIN97417.1 - 0.11 12.5 3.9 0.094 12.8 1.4 1.9 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family GldM_N PF12081.3 AIN97417.1 - 0.17 11.4 2.7 0.11 12.0 0.5 1.7 2 1 0 2 2 2 0 GldM N-terminal domain Prefoldin PF02996.12 AIN97417.1 - 0.17 11.5 5.7 3.7 7.2 0.0 2.7 2 1 0 2 2 2 0 Prefoldin subunit Poty_PP PF08440.5 AIN97417.1 - 0.26 10.3 1.9 0.16 10.9 0.3 1.4 2 0 0 2 2 2 0 Potyviridae polyprotein Flagellin_N PF00669.15 AIN97417.1 - 0.38 10.5 6.7 2.5 7.8 0.4 2.8 2 1 1 3 3 3 0 Bacterial flagellin N-terminal helical region RmuC PF02646.11 AIN97417.1 - 0.41 9.4 5.9 0.18 10.6 1.7 2.0 2 1 0 2 2 2 0 RmuC family APG6 PF04111.7 AIN97417.1 - 0.62 9.0 4.7 0.17 10.8 1.2 1.5 2 0 0 2 2 2 0 Autophagy protein Apg6 DUF2203 PF09969.4 AIN97417.1 - 1.7 8.8 4.3 20 5.4 3.0 2.4 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) DUF1691 PF07950.6 AIN97418.1 - 0.15 11.9 1.7 1.8 8.4 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1691) Apc3 PF12895.2 AIN97419.1 - 2.6e-08 33.8 21.6 3.6e-06 27.0 5.7 5.3 4 2 1 5 5 5 2 Anaphase-promoting complex, cyclosome, subunit 3 SRP72 PF08492.7 AIN97419.1 - 2.6e-07 30.8 0.3 2.6e-07 30.8 0.2 2.8 2 0 0 2 2 2 1 SRP72 RNA-binding domain TPR_12 PF13424.1 AIN97419.1 - 2.7e-05 24.0 21.4 0.094 12.6 0.1 5.3 4 1 2 6 6 6 3 Tetratricopeptide repeat TPR_19 PF14559.1 AIN97419.1 - 0.00026 21.2 36.2 0.049 13.9 0.4 7.8 4 2 3 8 8 8 3 Tetratricopeptide repeat TPR_16 PF13432.1 AIN97419.1 - 0.00028 21.4 39.9 0.11 13.2 0.3 8.3 6 2 1 8 8 8 2 Tetratricopeptide repeat TPR_17 PF13431.1 AIN97419.1 - 0.00032 20.6 4.5 15 6.0 0.0 5.4 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.1 AIN97419.1 - 0.0018 18.6 18.3 13 6.5 1.0 7.2 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_14 PF13428.1 AIN97419.1 - 0.0067 16.9 48.9 0.85 10.4 2.3 9.8 6 3 4 10 10 10 4 Tetratricopeptide repeat TPR_8 PF13181.1 AIN97419.1 - 0.11 12.3 8.2 2.2 8.2 0.2 4.1 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_2 PF07719.12 AIN97419.1 - 0.39 10.7 27.0 2.2 8.4 0.2 6.0 7 0 0 7 7 6 0 Tetratricopeptide repeat TPR_1 PF00515.23 AIN97419.1 - 1.4 8.6 13.3 6.1 6.6 0.2 4.5 4 0 0 4 4 4 0 Tetratricopeptide repeat ABC_tran PF00005.22 AIN97420.1 - 4.5e-42 143.5 0.0 2.1e-20 73.4 0.0 2.9 3 0 0 3 3 2 2 ABC transporter AAA_21 PF13304.1 AIN97420.1 - 4.6e-24 85.8 0.5 1.8e-08 34.6 0.1 4.2 3 1 0 3 3 3 3 AAA domain ABC_tran_2 PF12848.2 AIN97420.1 - 6.8e-23 80.3 5.3 6.4e-22 77.1 1.5 2.5 2 0 0 2 2 2 1 ABC transporter SMC_N PF02463.14 AIN97420.1 - 2.6e-11 43.1 1.2 0.0023 17.2 0.0 4.5 4 1 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_17 PF13207.1 AIN97420.1 - 2.3e-09 38.1 0.2 0.0018 19.1 0.0 3.6 3 1 0 3 3 3 2 AAA domain AAA_23 PF13476.1 AIN97420.1 - 2.5e-07 31.2 2.8 0.099 12.9 0.0 3.4 3 0 0 3 3 3 2 AAA domain AAA_28 PF13521.1 AIN97420.1 - 4.2e-07 30.0 0.0 0.013 15.4 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA PF00004.24 AIN97420.1 - 1.1e-06 28.8 0.0 0.0059 16.8 0.0 3.1 3 1 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.1 AIN97420.1 - 1.2e-06 28.4 0.1 0.096 12.5 0.0 3.2 3 0 0 3 3 3 2 AAA domain AAA_18 PF13238.1 AIN97420.1 - 1.6e-06 28.4 0.1 0.017 15.4 0.0 3.3 4 0 0 4 4 2 2 AAA domain AAA_29 PF13555.1 AIN97420.1 - 2.8e-06 26.7 0.1 0.096 12.2 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain RNA_helicase PF00910.17 AIN97420.1 - 3.2e-06 27.2 0.1 0.014 15.5 0.0 3.3 3 0 0 3 3 3 1 RNA helicase NACHT PF05729.7 AIN97420.1 - 5.2e-06 26.2 0.2 0.021 14.4 0.0 3.0 3 0 0 3 3 3 2 NACHT domain AAA_16 PF13191.1 AIN97420.1 - 5.8e-06 26.4 1.7 0.019 14.9 0.0 3.3 2 2 1 3 3 3 2 AAA ATPase domain AAA_14 PF13173.1 AIN97420.1 - 1.6e-05 24.8 0.0 0.74 9.7 0.0 3.8 4 0 0 4 4 4 2 AAA domain DUF258 PF03193.11 AIN97420.1 - 1.6e-05 24.1 0.0 0.12 11.4 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_22 PF13401.1 AIN97420.1 - 1.7e-05 24.9 0.0 0.03 14.4 0.0 3.0 2 1 0 2 2 2 1 AAA domain AAA_13 PF13166.1 AIN97420.1 - 2.1e-05 23.2 0.1 0.54 8.6 0.0 3.4 3 0 0 3 3 3 2 AAA domain AAA_5 PF07728.9 AIN97420.1 - 3.3e-05 23.6 0.1 0.034 13.8 0.0 2.6 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_25 PF13481.1 AIN97420.1 - 3.6e-05 23.2 0.0 0.25 10.7 0.0 3.1 2 1 0 2 2 2 2 AAA domain AAA_10 PF12846.2 AIN97420.1 - 0.00016 21.2 0.5 0.5 9.7 0.0 3.6 4 0 0 4 4 4 1 AAA-like domain MobB PF03205.9 AIN97420.1 - 0.00016 21.3 0.1 0.086 12.5 0.0 2.8 3 0 0 3 3 2 1 Molybdopterin guanine dinucleotide synthesis protein B Miro PF08477.8 AIN97420.1 - 0.00027 21.4 0.0 0.6 10.6 0.0 2.7 2 0 0 2 2 2 1 Miro-like protein UPF0079 PF02367.12 AIN97420.1 - 0.00048 19.7 0.1 0.0097 15.5 0.0 2.9 2 1 1 3 3 3 1 Uncharacterised P-loop hydrolase UPF0079 PduV-EutP PF10662.4 AIN97420.1 - 0.00071 19.0 0.0 0.26 10.7 0.0 2.5 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation MMR_HSR1 PF01926.18 AIN97420.1 - 0.0018 18.2 0.0 2 8.3 0.0 2.8 2 1 0 2 2 2 1 50S ribosome-binding GTPase Zeta_toxin PF06414.7 AIN97420.1 - 0.002 17.2 0.0 0.047 12.7 0.0 2.3 2 0 0 2 2 2 1 Zeta toxin SbcCD_C PF13558.1 AIN97420.1 - 0.0022 17.8 0.0 0.37 10.7 0.0 2.9 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_19 PF13245.1 AIN97420.1 - 0.0029 17.2 0.0 0.19 11.5 0.0 2.6 2 0 0 2 2 2 1 Part of AAA domain Arch_ATPase PF01637.13 AIN97420.1 - 0.003 17.2 0.0 1.1 8.9 0.0 2.7 3 0 0 3 3 2 1 Archaeal ATPase Mg_chelatase PF01078.16 AIN97420.1 - 0.0083 15.3 0.0 3.2 6.8 0.0 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI Rad17 PF03215.10 AIN97420.1 - 0.019 13.7 0.2 0.9 8.1 0.0 2.3 2 0 0 2 2 2 0 Rad17 cell cycle checkpoint protein ArgK PF03308.11 AIN97420.1 - 0.019 13.7 0.6 0.67 8.6 0.0 2.6 3 0 0 3 3 3 0 ArgK protein ATP-synt_ab PF00006.20 AIN97420.1 - 0.025 14.0 0.0 3.4 7.0 0.0 2.3 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain NB-ARC PF00931.17 AIN97420.1 - 0.03 13.2 0.0 4.9 5.9 0.0 2.5 2 0 0 2 2 2 0 NB-ARC domain NTPase_1 PF03266.10 AIN97420.1 - 0.031 13.9 0.1 0.8 9.4 0.0 2.4 2 0 0 2 2 2 0 NTPase SRP54 PF00448.17 AIN97420.1 - 0.033 13.6 0.1 0.67 9.3 0.0 2.4 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain cobW PF02492.14 AIN97420.1 - 0.034 13.5 0.2 2.5 7.5 0.0 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Sigma54_activ_2 PF14532.1 AIN97420.1 - 0.034 14.1 0.0 0.79 9.7 0.0 2.8 3 0 0 3 3 2 0 Sigma-54 interaction domain IstB_IS21 PF01695.12 AIN97420.1 - 0.042 13.2 0.0 2.5 7.5 0.0 2.4 2 0 0 2 2 2 0 IstB-like ATP binding protein VirE PF05272.6 AIN97420.1 - 0.043 13.2 0.0 16 4.8 0.0 3.1 3 0 0 3 3 3 0 Virulence-associated protein E RuvB_N PF05496.7 AIN97420.1 - 0.053 12.5 0.2 0.32 9.9 0.0 2.0 2 0 0 2 2 2 0 Holliday junction DNA helicase ruvB N-terminus AAA_24 PF13479.1 AIN97420.1 - 0.06 12.9 2.1 1.2 8.6 0.0 3.0 3 0 0 3 3 2 0 AAA domain Vps53_N PF04100.7 AIN97421.1 - 1.7e-64 218.0 11.9 2.3e-64 217.5 8.2 1.1 1 0 0 1 1 1 1 Vps53-like, N-terminal Ead_Ea22 PF13935.1 AIN97421.1 - 0.54 10.5 5.8 0.5 10.6 0.6 2.6 2 0 0 2 2 2 0 Ead/Ea22-like protein Atg8 PF02991.11 AIN97422.1 - 1e-09 38.2 0.0 1.4e-09 37.8 0.0 1.2 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like APG5 PF04106.7 AIN97422.1 - 0.026 13.9 0.0 0.026 13.9 0.0 1.2 1 0 0 1 1 1 0 Autophagy protein Apg5 CAP_GLY PF01302.20 AIN97424.1 - 5.6e-19 67.6 0.2 8.6e-19 67.0 0.2 1.3 1 0 0 1 1 1 1 CAP-Gly domain DUF1878 PF08963.5 AIN97424.1 - 0.12 12.6 6.0 0.14 12.4 0.7 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1878) PAS_7 PF12860.2 AIN97424.1 - 0.48 10.4 5.4 0.28 11.2 0.2 2.9 2 0 0 2 2 2 0 PAS fold Tropomyosin_1 PF12718.2 AIN97424.1 - 8.2 6.2 71.7 0.13 12.1 8.8 4.8 3 2 1 4 4 4 0 Tropomyosin like Dynein_light PF01221.13 AIN97426.1 - 8.7e-30 102.5 0.8 1e-29 102.3 0.6 1.1 1 0 0 1 1 1 1 Dynein light chain type 1 FKBP_C PF00254.23 AIN97427.1 - 6e-10 39.0 0.0 8.5e-10 38.5 0.0 1.2 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase FYVE PF01363.16 AIN97428.1 - 4.9e-12 45.5 14.2 8.6e-12 44.7 8.2 2.6 2 1 0 2 2 2 1 FYVE zinc finger zf-DHHC PF01529.15 AIN97428.1 - 0.18 11.2 2.0 0.44 9.9 1.4 1.6 1 0 0 1 1 1 0 DHHC palmitoyltransferase WD40 PF00400.27 AIN97429.1 - 1.1e-20 72.6 1.9 7.8e-07 28.7 0.2 7.0 7 0 0 7 7 7 5 WD domain, G-beta repeat eIF2A PF08662.6 AIN97429.1 - 0.0074 16.0 0.0 0.17 11.6 0.0 2.5 3 0 0 3 3 3 1 Eukaryotic translation initiation factor eIF2A PseudoU_synth_1 PF01416.15 AIN97430.1 - 1.9e-11 44.3 0.0 1.9e-08 34.6 0.0 3.5 3 0 0 3 3 3 1 tRNA pseudouridine synthase B5 PF03484.10 AIN97432.1 - 9.4e-18 63.8 0.1 1.2e-14 53.9 0.0 2.6 2 0 0 2 2 2 2 tRNA synthetase B5 domain B3_4 PF03483.12 AIN97432.1 - 4e-17 62.2 0.0 6.8e-17 61.4 0.0 1.3 1 0 0 1 1 1 1 B3/4 domain S-methyl_trans PF02574.11 AIN97434.1 - 0.035 13.3 0.0 0.059 12.6 0.0 1.2 1 0 0 1 1 1 0 Homocysteine S-methyltransferase DAGK_cat PF00781.19 AIN97436.1 - 6.6e-11 41.7 0.0 7.1e-08 31.9 0.0 2.8 2 0 0 2 2 2 2 Diacylglycerol kinase catalytic domain Mito_carr PF00153.22 AIN97439.1 - 3.2e-55 183.8 3.8 3.2e-18 65.2 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein PCI PF01399.22 AIN97440.1 - 3.7e-08 33.6 0.0 1.3e-07 31.8 0.0 2.0 2 0 0 2 2 2 1 PCI domain Ank_2 PF12796.2 AIN97441.1 - 5e-32 110.1 17.9 2.8e-06 27.5 0.1 12.2 11 2 0 12 12 12 6 Ankyrin repeats (3 copies) Ank PF00023.25 AIN97441.1 - 4.4e-27 92.5 25.9 1.7e-05 24.4 0.1 15.3 17 0 0 17 17 17 6 Ankyrin repeat Ank_3 PF13606.1 AIN97441.1 - 3.8e-20 69.9 26.5 0.0014 18.6 0.1 15.1 16 0 0 16 16 16 5 Ankyrin repeat Ank_4 PF13637.1 AIN97441.1 - 3.9e-14 52.7 11.2 0.24 11.9 0.0 11.5 13 0 0 13 13 13 3 Ankyrin repeats (many copies) Ank_5 PF13857.1 AIN97441.1 - 2.8e-13 49.6 31.0 0.0035 17.5 0.1 12.8 14 1 1 15 15 15 4 Ankyrin repeats (many copies) Na_trans_assoc PF06512.8 AIN97441.1 - 5.4 6.9 0.0 14 5.5 0.0 1.6 1 0 0 1 1 1 0 Sodium ion transport-associated SCP-1 PF05483.7 AIN97445.1 - 0.3 8.8 0.5 0.49 8.1 0.4 1.2 1 0 0 1 1 1 0 Synaptonemal complex protein 1 (SCP-1) CHCH PF06747.8 AIN97447.1 - 5.6e-06 26.1 1.3 9.3e-06 25.4 0.9 1.4 1 0 0 1 1 1 1 CHCH domain Cmc1 PF08583.5 AIN97447.1 - 0.039 13.7 1.2 0.075 12.8 0.8 1.4 1 0 0 1 1 1 0 Cytochrome c oxidase biogenesis protein Cmc1 like COX17 PF05051.8 AIN97447.1 - 0.043 13.8 1.8 0.44 10.6 0.3 2.2 1 1 1 2 2 2 0 Cytochrome C oxidase copper chaperone (COX17) DUF1903 PF08991.5 AIN97447.1 - 0.053 13.6 0.2 0.076 13.1 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1903) Actin PF00022.14 AIN97448.1 - 1.1e-76 257.8 0.0 1.2e-76 257.6 0.0 1.0 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.8 AIN97448.1 - 0.091 11.3 0.0 7.1 5.1 0.0 2.3 2 0 0 2 2 2 0 MreB/Mbl protein Fcf1 PF04900.7 AIN97449.1 - 5.1e-36 122.8 1.8 1e-35 121.8 1.2 1.5 1 0 0 1 1 1 1 Fcf1 Thioredoxin PF00085.15 AIN97450.1 - 0.038 13.6 0.1 0.12 12.0 0.1 1.8 1 1 0 1 1 1 0 Thioredoxin Filament_head PF04732.9 AIN97451.1 - 0.16 12.6 1.5 0.41 11.3 0.6 2.0 1 1 0 1 1 1 0 Intermediate filament head (DNA binding) region LEA_3 PF03242.8 AIN97451.1 - 0.46 10.7 3.6 0.65 10.2 0.1 2.7 2 1 1 3 3 3 0 Late embryogenesis abundant protein DUF1145 PF06611.7 AIN97452.1 - 0.081 12.5 1.2 0.56 9.8 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1145) Pex2_Pex12 PF04757.9 AIN97453.1 - 3.9e-38 131.1 0.2 5.7e-38 130.5 0.2 1.3 1 1 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4_2 PF13923.1 AIN97453.1 - 0.00096 19.1 4.5 0.0016 18.3 3.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 AIN97453.1 - 0.0087 15.8 3.5 0.016 15.0 2.4 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 AIN97453.1 - 0.078 12.6 5.5 0.29 10.8 3.9 1.8 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Surp PF01805.15 AIN97455.1 - 1.3e-08 34.3 2.2 1.3e-08 34.3 1.5 2.1 2 1 0 2 2 2 1 Surp module Band_7 PF01145.20 AIN97456.1 - 1e-28 100.4 0.2 3.2e-28 98.8 0.0 1.7 2 0 0 2 2 2 1 SPFH domain / Band 7 family Band_7_1 PF13421.1 AIN97456.1 - 0.0046 16.5 0.0 0.011 15.2 0.0 1.7 1 0 0 1 1 1 1 SPFH domain-Band 7 family Band_7 PF01145.20 AIN97457.1 - 3.7e-23 82.3 0.0 5e-23 81.9 0.0 1.2 1 0 0 1 1 1 1 SPFH domain / Band 7 family SH3_4 PF06347.8 AIN97458.1 - 0.027 14.0 0.0 0.068 12.7 0.0 1.6 1 0 0 1 1 1 0 Bacterial SH3 domain MBOAT PF03062.14 AIN97462.1 - 8.8e-20 71.0 11.6 8.8e-20 71.0 8.0 1.6 2 0 0 2 2 2 1 MBOAT, membrane-bound O-acyltransferase family BPD_transp_2 PF02653.11 AIN97462.1 - 0.0063 15.5 3.4 0.01 14.8 2.3 1.3 1 1 0 1 1 1 1 Branched-chain amino acid transport system / permease component MBOAT_2 PF13813.1 AIN97462.1 - 0.094 12.8 4.2 0.33 11.0 1.9 2.2 2 0 0 2 2 2 0 Membrane bound O-acyl transferase family PAP2 PF01569.16 AIN97463.1 - 3.5e-20 71.9 3.3 3.5e-20 71.9 2.3 2.1 2 0 0 2 2 2 1 PAP2 superfamily Mtp PF03821.11 AIN97463.1 - 0.017 14.5 0.7 0.037 13.4 0.5 1.5 1 0 0 1 1 1 0 Golgi 4-transmembrane spanning transporter PAP2_3 PF14378.1 AIN97463.1 - 0.019 14.4 0.0 0.051 13.1 0.0 1.7 1 0 0 1 1 1 0 PAP2 superfamily DUF4199 PF13858.1 AIN97463.1 - 4 7.3 6.0 1.8 8.4 0.2 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF4199) EI24 PF07264.6 AIN97464.1 - 0.0062 15.9 1.7 0.0073 15.7 1.2 1.1 1 0 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) Scs3p PF10261.4 AIN97464.1 - 0.033 13.2 0.8 0.039 12.9 0.5 1.0 1 0 0 1 1 1 0 Inositol phospholipid synthesis and fat-storage-inducing TM Sar8_2 PF03058.9 AIN97464.1 - 0.049 13.9 1.2 0.071 13.4 0.9 1.4 1 1 0 1 1 1 0 Sar8.2 family DUF1467 PF07330.7 AIN97464.1 - 0.054 13.2 0.6 0.064 13.0 0.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1467) 7tm_1 PF00001.16 AIN97464.1 - 0.055 12.5 3.1 0.058 12.5 2.2 1.0 1 0 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) DUF3311 PF11755.3 AIN97464.1 - 0.084 12.4 3.6 0.27 10.8 1.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3311) DUF898 PF05987.8 AIN97464.1 - 0.13 11.1 1.1 0.14 11.0 0.7 1.0 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF898) Sec20 PF03908.8 AIN97464.1 - 0.85 9.3 2.5 30 4.4 0.9 2.2 2 0 0 2 2 2 0 Sec20 DUF912 PF06024.7 AIN97464.1 - 1.1 9.3 5.2 0.59 10.2 0.1 2.0 1 1 1 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) DUF2975 PF11188.3 AIN97464.1 - 6.2 6.5 9.4 7.7 6.2 1.0 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2975) DUF454 PF04304.8 AIN97464.1 - 7.7 6.6 10.1 0.58 10.2 0.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF454) DUF1067 PF06362.6 AIN97465.1 - 0.12 12.9 0.2 0.44 11.1 0.0 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1067) PDZ_2 PF13180.1 AIN97466.1 - 0.0023 17.7 0.0 0.019 14.8 0.0 2.4 2 1 1 3 3 3 1 PDZ domain PDZ PF00595.19 AIN97466.1 - 0.0023 18.0 0.0 0.0052 16.9 0.0 1.5 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) SlyX PF04102.7 AIN97466.1 - 4.1 7.8 7.4 14 6.1 0.0 3.4 4 0 0 4 4 4 0 SlyX Cation_efflux PF01545.16 AIN97467.1 - 3.9e-31 108.1 12.9 1.1e-30 106.7 5.2 2.9 2 1 0 2 2 2 1 Cation efflux family TBP PF00352.16 AIN97468.1 - 1.5e-32 110.7 0.0 4.6e-18 64.3 0.0 2.8 2 1 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) TPR_2 PF07719.12 AIN97469.1 - 7.4e-09 34.8 7.9 0.00026 20.6 0.0 5.4 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_17 PF13431.1 AIN97469.1 - 1e-08 34.6 0.2 0.0051 16.9 0.0 4.0 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.23 AIN97469.1 - 3.6e-07 29.5 4.9 0.0014 18.1 0.0 4.2 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_11 PF13414.1 AIN97469.1 - 1.9e-06 27.3 3.2 0.35 10.5 0.2 4.5 3 2 3 6 6 6 4 TPR repeat TPR_14 PF13428.1 AIN97469.1 - 1.9e-05 24.8 0.0 0.22 12.2 0.0 4.0 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.1 AIN97469.1 - 2.8e-05 23.9 1.0 0.0018 18.1 0.1 3.4 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.1 AIN97469.1 - 5.1e-05 22.7 2.5 0.006 16.2 0.0 4.3 5 1 0 5 5 5 1 Tetratricopeptide repeat TPR_6 PF13174.1 AIN97469.1 - 0.00098 19.4 2.9 0.4 11.2 0.3 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.1 AIN97469.1 - 0.0026 18.3 0.2 3 8.6 0.0 3.6 4 1 1 5 5 4 1 Tetratricopeptide repeat TPR_7 PF13176.1 AIN97469.1 - 0.015 15.0 0.6 0.084 12.7 0.3 2.4 1 1 0 1 1 1 0 Tetratricopeptide repeat Sel1 PF08238.7 AIN97469.1 - 0.016 15.8 3.1 7.5 7.3 0.1 3.3 3 0 0 3 3 3 0 Sel1 repeat TOM20_plant PF06552.7 AIN97469.1 - 0.11 12.1 0.2 2.4 7.7 0.0 2.6 2 1 1 3 3 3 0 Plant specific mitochondrial import receptor subunit TOM20 TPR_19 PF14559.1 AIN97469.1 - 0.12 12.6 0.3 7 7.0 0.0 3.2 4 1 0 4 4 3 0 Tetratricopeptide repeat PAP_assoc PF03828.14 AIN97470.1 - 1.2e-10 41.2 0.0 4.4e-10 39.3 0.1 2.0 2 0 0 2 2 2 1 Cid1 family poly A polymerase Peptidase_C1 PF00112.18 AIN97471.1 - 1.3e-68 231.2 5.7 2e-68 230.5 4.0 1.3 1 0 0 1 1 1 1 Papain family cysteine protease DUF3586 PF12131.3 AIN97471.1 - 1.4e-23 82.6 7.2 1.4e-23 82.6 5.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF3586) Inhibitor_I29 PF08246.7 AIN97471.1 - 1.9e-08 34.4 0.7 3.1e-08 33.7 0.5 1.4 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.10 AIN97471.1 - 0.0023 16.5 2.8 0.019 13.4 0.0 2.6 3 0 0 3 3 3 1 Peptidase C1-like family RVT_1 PF00078.22 AIN97472.1 - 5.2e-05 22.7 0.0 9.5e-05 21.8 0.0 1.4 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) PIH1 PF08190.7 AIN97473.1 - 3.4e-15 56.3 0.5 9.3e-09 35.1 0.0 2.2 2 0 0 2 2 2 2 pre-RNA processing PIH1/Nop17 Pkinase PF00069.20 AIN97474.1 - 2.1e-67 227.0 0.0 2.4e-67 226.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AIN97474.1 - 7.4e-34 116.9 0.0 1.1e-33 116.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 AIN97474.1 - 6.5e-07 28.6 0.0 9.6e-07 28.0 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 AIN97474.1 - 0.0014 18.4 0.0 0.0026 17.5 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 AIN97474.1 - 0.037 13.0 0.2 0.078 12.0 0.1 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family NAD_binding_1 PF00175.16 AIN97475.1 - 3.3e-12 46.9 0.0 5.6e-12 46.2 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Oxidored-like PF09791.4 AIN97475.1 - 1.1e-11 44.0 1.0 2.2e-11 43.0 0.7 1.5 1 0 0 1 1 1 1 Oxidoreductase-like protein, N-terminal FAD_binding_1 PF00667.15 AIN97475.1 - 2.3e-05 23.9 0.0 0.016 14.6 0.0 2.3 2 0 0 2 2 2 2 FAD binding domain NAD_binding_6 PF08030.7 AIN97475.1 - 0.12 12.2 0.1 19 5.1 0.0 2.3 2 0 0 2 2 2 0 Ferric reductase NAD binding domain COX6B PF02297.12 AIN97476.1 - 0.077 13.0 1.7 0.13 12.3 1.2 1.5 1 1 0 1 1 1 0 Cytochrome oxidase c subunit VIb Pkinase PF00069.20 AIN97477.1 - 5.5e-40 137.1 0.0 5.1e-26 91.3 0.0 2.6 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 AIN97477.1 - 5.1e-18 65.0 0.0 1.3e-14 53.9 0.0 2.4 2 0 0 2 2 2 2 Protein tyrosine kinase zf-UDP PF14569.1 AIN97477.1 - 0.13 12.0 6.4 1.2 8.9 4.4 2.3 1 1 0 1 1 1 0 Zinc-binding RING-finger IF4E PF01652.13 AIN97478.1 - 3.2e-43 147.1 0.0 4.2e-43 146.7 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E TPT PF03151.11 AIN97480.1 - 1.4e-23 83.2 8.1 1.4e-23 83.2 5.6 2.4 1 1 0 2 2 2 1 Triose-phosphate Transporter family UAA PF08449.6 AIN97480.1 - 0.00066 18.6 24.0 0.0011 18.0 16.7 1.2 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.15 AIN97480.1 - 0.0013 18.8 10.6 0.0013 18.8 7.4 3.1 1 1 2 3 3 3 2 EamA-like transporter family EmrE PF13536.1 AIN97480.1 - 0.19 11.9 24.1 0.049 13.8 5.0 2.8 2 1 1 3 3 3 0 Multidrug resistance efflux transporter FKBP_C PF00254.23 AIN97482.1 - 1.7e-31 108.0 0.0 3.1e-30 104.0 0.0 2.6 2 0 0 2 2 2 1 FKBP-type peptidyl-prolyl cis-trans isomerase TPR_11 PF13414.1 AIN97482.1 - 3.4e-11 42.6 0.4 2.5e-05 23.8 0.0 2.6 1 1 1 2 2 2 2 TPR repeat TPR_1 PF00515.23 AIN97482.1 - 1.2e-07 30.9 0.0 0.018 14.6 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.12 AIN97482.1 - 5.6e-07 28.9 0.1 0.016 15.0 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.1 AIN97482.1 - 1.1e-05 25.6 0.2 0.00018 21.7 0.0 2.3 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.1 AIN97482.1 - 1.2e-05 25.1 0.1 0.004 17.0 0.0 2.8 1 1 1 2 2 2 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 AIN97482.1 - 2.1e-05 24.3 0.0 5.9e-05 22.8 0.0 1.8 1 0 0 1 1 1 1 Fis1 C-terminal tetratricopeptide repeat TPR_16 PF13432.1 AIN97482.1 - 3.7e-05 24.2 0.3 3 8.6 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.1 AIN97482.1 - 8.1e-05 22.9 0.2 0.032 14.8 0.0 3.4 2 1 1 3 3 3 1 Tetratricopeptide repeat Apc3 PF12895.2 AIN97482.1 - 0.00041 20.4 0.0 0.00076 19.5 0.0 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.1 AIN97482.1 - 0.0011 18.6 0.1 0.063 13.1 0.0 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_17 PF13431.1 AIN97482.1 - 0.0024 17.9 0.1 0.32 11.3 0.1 3.7 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_6 PF13174.1 AIN97482.1 - 0.038 14.4 0.4 0.4 11.2 0.0 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.1 AIN97482.1 - 0.067 13.0 0.0 5.1 7.1 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat OSCP PF00213.13 AIN97482.1 - 0.07 12.9 0.5 0.16 11.8 0.2 1.6 2 0 0 2 2 2 0 ATP synthase delta (OSCP) subunit Carn_acyltransf PF00755.15 AIN97483.1 - 1e-122 410.2 0.0 6.4e-89 298.6 0.0 2.0 1 1 0 2 2 2 2 Choline/Carnitine o-acyltransferase Herpes_UL4 PF03277.8 AIN97483.1 - 0.039 13.1 0.0 15 4.7 0.0 3.3 3 0 0 3 3 3 0 Herpesvirus UL4 family WD40 PF00400.27 AIN97484.1 - 1.6e-11 43.6 8.0 1e-05 25.1 0.1 5.5 6 0 0 6 6 6 3 WD domain, G-beta repeat IMPDH PF00478.20 AIN97485.1 - 1.6e-130 435.0 4.0 1.9e-130 434.8 2.7 1.0 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain CBS PF00571.23 AIN97485.1 - 1.2e-12 47.4 0.1 1.9e-05 24.3 0.0 2.5 2 0 0 2 2 2 2 CBS domain FMN_dh PF01070.13 AIN97485.1 - 1.2e-09 37.5 0.2 1.2e-09 37.5 0.2 1.6 2 0 0 2 2 2 1 FMN-dependent dehydrogenase NMO PF03060.10 AIN97485.1 - 9e-07 28.3 2.3 0.016 14.4 0.7 2.5 3 0 0 3 3 3 2 Nitronate monooxygenase His_biosynth PF00977.16 AIN97485.1 - 0.053 12.7 0.9 0.82 8.8 0.0 2.5 2 1 1 3 3 3 0 Histidine biosynthesis protein ELMO_CED12 PF04727.8 AIN97486.1 - 1.8e-30 105.7 0.0 2.8e-30 105.1 0.0 1.3 1 0 0 1 1 1 1 ELMO/CED-12 family Peptidase_M41 PF01434.13 AIN97488.1 - 3e-45 154.3 0.2 4.6e-45 153.7 0.1 1.3 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.24 AIN97488.1 - 5.5e-41 139.8 0.1 1.3e-39 135.4 0.0 2.4 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 AIN97488.1 - 6.3e-05 23.7 0.0 0.00021 22.0 0.0 1.9 2 0 0 2 2 1 1 AAA domain AAA_19 PF13245.1 AIN97488.1 - 0.00015 21.4 1.0 0.001 18.7 0.0 2.7 2 0 0 2 2 2 1 Part of AAA domain AAA_5 PF07728.9 AIN97488.1 - 0.00025 20.7 0.0 0.00079 19.1 0.0 1.9 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 AIN97488.1 - 0.00028 20.9 6.6 0.016 15.1 0.1 4.0 3 1 1 4 4 4 1 AAA ATPase domain AAA_22 PF13401.1 AIN97488.1 - 0.00053 20.1 1.2 0.0089 16.1 0.1 3.0 2 1 0 2 2 2 1 AAA domain AAA_14 PF13173.1 AIN97488.1 - 0.0025 17.6 0.0 0.0055 16.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.7 AIN97488.1 - 0.0044 16.1 0.0 0.013 14.5 0.0 1.9 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_25 PF13481.1 AIN97488.1 - 0.019 14.3 1.4 0.14 11.5 0.3 2.5 1 1 1 2 2 2 0 AAA domain IstB_IS21 PF01695.12 AIN97488.1 - 0.023 14.1 0.1 0.059 12.7 0.1 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein DUF2075 PF09848.4 AIN97488.1 - 0.025 13.5 0.0 0.044 12.7 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Peptidase_M50B PF13398.1 AIN97488.1 - 0.03 13.7 0.0 0.066 12.5 0.0 1.5 1 0 0 1 1 1 0 Peptidase M50B-like AAA_3 PF07726.6 AIN97488.1 - 0.036 13.6 0.0 0.92 9.1 0.0 2.5 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.1 AIN97488.1 - 0.055 13.7 0.0 0.16 12.2 0.0 1.8 1 0 0 1 1 1 0 AAA domain TIP49 PF06068.8 AIN97488.1 - 0.064 11.9 0.0 0.14 10.8 0.0 1.5 1 0 0 1 1 1 0 TIP49 C-terminus AAA_28 PF13521.1 AIN97488.1 - 0.066 13.1 0.0 0.22 11.4 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_2 PF07724.9 AIN97488.1 - 0.099 12.5 0.2 0.81 9.5 0.1 2.4 1 1 0 1 1 1 0 AAA domain (Cdc48 subfamily) SRP19 PF01922.12 AIN97489.1 - 3.3e-27 94.9 0.2 8e-27 93.6 0.1 1.7 1 1 0 1 1 1 1 SRP19 protein Pkinase PF00069.20 AIN97490.1 - 1.1e-19 70.6 0.0 1.4e-19 70.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AIN97490.1 - 4.3e-07 29.2 0.0 1e-06 28.0 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase BTB_2 PF02214.17 AIN97491.1 - 4e-15 55.7 0.0 1e-14 54.5 0.0 1.6 1 0 0 1 1 1 1 BTB/POZ domain Atg8 PF02991.11 AIN97492.1 - 1.5e-38 130.9 0.0 1.7e-38 130.7 0.0 1.0 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like APG12 PF04110.8 AIN97492.1 - 8.1e-08 32.3 0.0 1e-07 32.0 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 START PF01852.14 AIN97493.1 - 0.00011 21.6 0.0 0.00019 20.8 0.0 1.4 1 1 0 1 1 1 1 START domain PseudoU_synth_1 PF01416.15 AIN97494.1 - 2.1e-18 66.6 0.3 2e-10 41.0 0.0 3.4 2 1 0 2 2 2 2 tRNA pseudouridine synthase WD40 PF00400.27 AIN97495.1 - 1.8e-21 75.1 0.9 0.00037 20.2 0.0 6.5 6 0 0 6 6 6 5 WD domain, G-beta repeat Nup160 PF11715.3 AIN97495.1 - 0.05 11.7 0.0 5.3 5.0 0.0 2.7 2 1 0 2 2 2 0 Nucleoporin Nup120/160 Mon1 PF03164.9 AIN97496.1 - 3.4e-24 85.2 0.0 1.6e-15 56.6 0.0 2.4 2 1 0 2 2 2 2 Trafficking protein Mon1 Peptidase_C2 PF00648.16 AIN97497.1 - 0.00081 18.4 0.0 0.0017 17.4 0.0 1.4 1 0 0 1 1 1 1 Calpain family cysteine protease Pyr_redox_2 PF07992.9 AIN97498.1 - 1.2e-07 31.8 0.0 1.2e-05 25.2 0.0 2.5 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 AIN97498.1 - 0.00022 21.1 0.1 0.00079 19.3 0.1 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 AIN97498.1 - 0.00032 19.7 1.0 0.0015 17.5 0.1 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 AIN97498.1 - 0.00089 18.2 0.3 0.0018 17.2 0.2 1.5 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_Gly3P_dh_N PF01210.18 AIN97498.1 - 0.0052 16.5 0.1 0.0093 15.7 0.0 1.4 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Trp_halogenase PF04820.9 AIN97498.1 - 0.0065 15.1 0.2 0.011 14.4 0.2 1.3 1 0 0 1 1 1 1 Tryptophan halogenase NAD_binding_9 PF13454.1 AIN97498.1 - 0.039 13.7 1.9 0.2 11.4 0.1 2.9 3 0 0 3 3 3 0 FAD-NAD(P)-binding Pyr_redox PF00070.22 AIN97498.1 - 0.043 14.2 0.3 0.47 10.8 0.2 2.6 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase DUF3115 PF11312.3 AIN97498.1 - 0.057 12.2 0.0 0.087 11.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3115) FAD_binding_3 PF01494.14 AIN97498.1 - 0.094 11.7 0.8 0.28 10.2 0.1 2.0 2 0 0 2 2 2 0 FAD binding domain Thi4 PF01946.12 AIN97498.1 - 0.11 11.5 0.0 0.21 10.6 0.0 1.3 1 0 0 1 1 1 0 Thi4 family TrkA_N PF02254.13 AIN97498.1 - 0.12 12.3 0.1 0.28 11.1 0.1 1.7 1 1 0 1 1 1 0 TrkA-N domain GRAS PF03514.9 AIN97498.1 - 0.13 10.9 0.0 0.27 9.9 0.0 1.4 1 0 0 1 1 1 0 GRAS domain family HI0933_like PF03486.9 AIN97498.1 - 0.15 10.5 0.8 1.1 7.7 0.2 2.3 2 0 0 2 2 2 0 HI0933-like protein Mqo PF06039.10 AIN97498.1 - 0.16 10.1 0.0 0.23 9.5 0.0 1.1 1 0 0 1 1 1 0 Malate:quinone oxidoreductase (Mqo) RIIa PF02197.12 AIN97499.1 - 1.7e-05 24.1 0.2 3.2e-05 23.2 0.1 1.6 1 0 0 1 1 1 1 Regulatory subunit of type II PKA R-subunit Dpy-30 PF05186.8 AIN97499.1 - 5.7e-05 22.5 0.0 0.0001 21.7 0.0 1.5 1 1 0 1 1 1 1 Dpy-30 motif TSC22 PF01166.13 AIN97499.1 - 0.054 13.4 0.1 0.099 12.6 0.1 1.5 1 0 0 1 1 1 0 TSC-22/dip/bun family DUF501 PF04417.7 AIN97499.1 - 0.15 11.8 0.6 12 5.7 0.3 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF501) Baculo_PEP_C PF04513.7 AIN97502.1 - 0.018 14.8 20.3 0.13 12.0 1.8 4.6 3 1 1 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus Reo_sigmaC PF04582.7 AIN97502.1 - 0.12 11.4 7.8 0.26 10.4 0.7 3.3 2 1 1 3 3 3 0 Reovirus sigma C capsid protein EMP24_GP25L PF01105.19 AIN97503.1 - 2.3e-11 43.7 0.3 7.8e-11 42.0 0.2 1.8 1 1 0 1 1 1 1 emp24/gp25L/p24 family/GOLD CS PF04969.11 AIN97504.1 - 1.1e-08 35.4 0.0 1.7e-08 34.8 0.0 1.3 1 0 0 1 1 1 1 CS domain DUF1935 PF09149.5 AIN97505.1 - 5e-115 376.6 0.1 1.7e-29 101.8 0.0 4.1 4 0 0 4 4 4 4 Domain of unknown function (DUF1935) DUF1935 PF09149.5 AIN97506.1 - 4.2e-123 402.6 7.3 1.1e-32 112.0 0.1 4.0 4 0 0 4 4 4 4 Domain of unknown function (DUF1935) Glyco_hydro_26 PF02156.10 AIN97506.1 - 0.0056 16.1 0.0 0.97 8.8 0.0 2.4 2 0 0 2 2 2 2 Glycosyl hydrolase family 26 Methyltransf_26 PF13659.1 AIN97507.1 - 0.0003 20.7 0.6 0.0014 18.5 0.4 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 AIN97507.1 - 0.056 14.0 0.3 0.14 12.7 0.2 1.7 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_25 PF13649.1 AIN97507.1 - 0.15 12.3 0.1 0.39 11.1 0.1 1.7 1 0 0 1 1 1 0 Methyltransferase domain Nop25 PF09805.4 AIN97509.1 - 1e-07 32.1 17.8 1e-07 32.1 12.3 3.0 2 1 0 2 2 2 1 Nucleolar protein 12 (25kDa) Ldh_1_N PF00056.18 AIN97510.1 - 2.7e-43 147.1 0.0 3.7e-43 146.7 0.0 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.13 AIN97510.1 - 4e-37 127.6 0.0 5.4e-37 127.1 0.0 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Semialdhyde_dh PF01118.19 AIN97510.1 - 0.015 15.6 0.0 0.053 13.8 0.0 1.9 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain 3Beta_HSD PF01073.14 AIN97510.1 - 0.018 13.7 0.0 0.028 13.1 0.0 1.3 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family THF_DHG_CYH_C PF02882.14 AIN97510.1 - 0.036 13.1 0.1 0.33 10.0 0.1 2.1 1 1 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Glyco_hydro_3_C PF01915.17 AIN97510.1 - 0.12 11.8 0.1 0.37 10.2 0.0 1.8 2 0 0 2 2 2 0 Glycosyl hydrolase family 3 C-terminal domain Ldh_1_N PF00056.18 AIN97511.1 - 8.9e-37 126.0 0.0 1.2e-36 125.5 0.0 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.13 AIN97511.1 - 2.2e-33 115.4 0.0 3.4e-33 114.8 0.0 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain 3Beta_HSD PF01073.14 AIN97511.1 - 0.0016 17.2 0.0 0.0023 16.6 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Semialdhyde_dh PF01118.19 AIN97511.1 - 0.0087 16.3 0.0 0.017 15.4 0.0 1.5 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain THF_DHG_CYH_C PF02882.14 AIN97511.1 - 0.031 13.3 0.0 0.19 10.7 0.0 2.2 1 1 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain DapB_N PF01113.15 AIN97511.1 - 0.064 13.1 0.0 0.12 12.3 0.0 1.4 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Ldh_1_N PF00056.18 AIN97512.1 - 3.8e-46 156.4 0.2 5.1e-46 156.0 0.1 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.13 AIN97512.1 - 4.3e-41 140.5 0.0 6.5e-41 139.9 0.0 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain DapB_N PF01113.15 AIN97512.1 - 0.00059 19.7 0.0 0.0014 18.5 0.0 1.6 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus Semialdhyde_dh PF01118.19 AIN97512.1 - 0.0012 19.1 0.1 0.0046 17.2 0.0 2.0 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain 3Beta_HSD PF01073.14 AIN97512.1 - 0.0021 16.8 0.0 0.0029 16.3 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Saccharop_dh PF03435.13 AIN97512.1 - 0.0025 16.8 0.1 0.0036 16.3 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase Epimerase PF01370.16 AIN97512.1 - 0.058 12.8 0.0 0.092 12.1 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Peptidase_M8 PF01457.11 AIN97512.1 - 0.082 11.2 0.0 0.13 10.5 0.0 1.2 1 0 0 1 1 1 0 Leishmanolysin Ldh_1_C PF02866.13 AIN97513.1 - 2.1e-15 56.8 0.0 6e-15 55.4 0.0 1.7 1 1 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Ldh_1_N PF00056.18 AIN97513.1 - 5.4e-13 48.9 0.0 8.2e-13 48.3 0.0 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain THF_DHG_CYH_C PF02882.14 AIN97513.1 - 0.11 11.5 0.1 0.39 9.7 0.0 1.9 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain ADK PF00406.17 AIN97514.1 - 6.6e-24 84.5 0.0 8.7e-24 84.1 0.0 1.0 1 0 0 1 1 1 1 Adenylate kinase ADK_lid PF05191.9 AIN97514.1 - 7.9e-10 38.2 0.0 1.4e-09 37.3 0.0 1.5 1 0 0 1 1 1 1 Adenylate kinase, active site lid AAA_17 PF13207.1 AIN97514.1 - 6.6e-08 33.4 0.0 1.2e-07 32.6 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 AIN97514.1 - 0.0012 19.2 0.0 0.0028 17.9 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.1 AIN97514.1 - 0.0015 18.4 0.0 0.0032 17.4 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 AIN97514.1 - 0.028 14.3 0.0 0.045 13.6 0.0 1.5 1 1 0 1 1 1 0 AAA domain AAA PF00004.24 AIN97514.1 - 0.1 12.8 0.2 0.4 10.8 0.0 2.1 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.1 AIN97514.1 - 0.11 12.3 0.0 0.18 11.6 0.0 1.5 1 1 0 1 1 1 0 AAA domain RuvB_N PF05496.7 AIN97514.1 - 0.12 11.4 0.0 0.28 10.2 0.0 1.5 1 1 1 2 2 2 0 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 AIN97514.1 - 0.13 12.0 0.0 0.33 10.7 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain ADK PF00406.17 AIN97515.1 - 2.8e-50 170.1 0.0 3.3e-50 169.8 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase ADK_lid PF05191.9 AIN97515.1 - 9.5e-13 47.5 0.1 2.3e-12 46.3 0.0 1.6 1 0 0 1 1 1 1 Adenylate kinase, active site lid AAA_17 PF13207.1 AIN97515.1 - 1.8e-07 31.9 0.0 3.4e-07 31.1 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 AIN97515.1 - 0.00085 19.2 0.0 0.0014 18.5 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.1 AIN97515.1 - 0.016 15.1 0.2 0.12 12.3 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.1 AIN97515.1 - 0.018 15.3 0.0 0.098 12.9 0.0 2.1 2 1 0 2 2 2 0 AAA domain Herpes_UL52 PF03121.10 AIN97516.1 - 0.13 11.9 6.7 0.29 10.9 4.7 1.5 1 0 0 1 1 1 0 Herpesviridae UL52/UL70 DNA primase adh_short PF00106.20 AIN97518.1 - 7.9e-20 71.4 0.0 1.1e-19 71.0 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 AIN97518.1 - 4.2e-07 29.9 0.0 6.2e-07 29.4 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 AIN97518.1 - 3.6e-06 26.7 0.0 5.3e-06 26.2 0.0 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 AIN97518.1 - 0.03 14.3 0.0 0.058 13.4 0.0 1.6 1 1 0 1 1 1 0 NADH(P)-binding Creatinase_N PF01321.13 AIN97518.1 - 0.11 13.0 0.0 0.35 11.3 0.0 1.8 2 1 0 2 2 2 0 Creatinase/Prolidase N-terminal domain Pkinase PF00069.20 AIN97520.1 - 5e-42 143.8 0.0 6.2e-42 143.5 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AIN97520.1 - 2.8e-23 82.3 0.0 3.3e-23 82.0 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 AIN97520.1 - 2.8e-07 29.7 0.0 1.6e-06 27.3 0.0 1.9 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 AIN97520.1 - 0.011 15.4 0.0 0.081 12.6 0.0 1.9 1 1 1 2 2 2 0 Phosphotransferase enzyme family PIP49_C PF12260.3 AIN97520.1 - 0.1 12.0 0.0 0.15 11.4 0.0 1.3 1 0 0 1 1 1 0 Protein-kinase domain of FAM69 Choline_kinase PF01633.15 AIN97520.1 - 0.13 11.8 0.0 0.21 11.1 0.0 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase DnaJ PF00226.26 AIN97521.1 - 3.8e-14 52.1 0.0 8.4e-14 51.0 0.0 1.6 1 0 0 1 1 1 1 DnaJ domain Ferric_reduct PF01794.14 AIN97521.1 - 0.27 11.3 5.7 0.47 10.5 1.0 3.0 3 0 0 3 3 3 0 Ferric reductase like transmembrane component CLPTM1 PF05602.7 AIN97522.1 - 1.3e-126 422.8 0.0 1.6e-126 422.6 0.0 1.1 1 0 0 1 1 1 1 Cleft lip and palate transmembrane protein 1 (CLPTM1) peroxidase PF00141.18 AIN97524.1 - 1.3e-49 168.8 0.0 2e-49 168.1 0.0 1.3 1 0 0 1 1 1 1 Peroxidase G6PD_C PF02781.11 AIN97525.1 - 5.6e-117 389.7 0.0 7.4e-117 389.3 0.0 1.1 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, C-terminal domain G6PD_N PF00479.17 AIN97525.1 - 3.9e-58 196.7 0.0 7.9e-58 195.6 0.0 1.5 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, NAD binding domain RIIa PF02197.12 AIN97525.1 - 0.00075 18.8 0.3 0.0033 16.8 0.1 2.0 2 0 0 2 2 2 1 Regulatory subunit of type II PKA R-subunit DS PF01916.12 AIN97526.1 - 2.1e-55 187.9 0.0 3.1e-37 128.2 0.0 4.1 4 0 0 4 4 4 4 Deoxyhypusine synthase AAA PF00004.24 AIN97527.1 - 1.1e-09 38.6 0.1 6e-07 29.7 0.0 2.5 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 AIN97527.1 - 3.7e-07 29.9 0.0 8.3e-07 28.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_17 PF13207.1 AIN97527.1 - 4.3e-06 27.5 0.0 1.2e-05 26.1 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 AIN97527.1 - 0.0011 19.0 0.0 0.0028 17.6 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain AAA_19 PF13245.1 AIN97527.1 - 0.0014 18.3 0.0 0.0091 15.7 0.0 2.3 2 0 0 2 2 2 1 Part of AAA domain AAA_33 PF13671.1 AIN97527.1 - 0.0015 18.4 0.0 0.0049 16.7 0.0 1.8 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.17 AIN97527.1 - 0.0021 18.2 0.0 0.0062 16.7 0.0 1.8 1 0 0 1 1 1 1 RNA helicase AAA_2 PF07724.9 AIN97527.1 - 0.0048 16.8 0.0 0.0098 15.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_28 PF13521.1 AIN97527.1 - 0.0066 16.4 0.5 0.018 14.9 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.1 AIN97527.1 - 0.0095 15.5 0.2 0.14 11.7 0.0 2.5 3 0 0 3 3 3 1 AAA domain AAA_18 PF13238.1 AIN97527.1 - 0.013 15.8 0.0 0.03 14.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain Viral_helicase1 PF01443.13 AIN97527.1 - 0.014 14.9 0.0 0.056 12.9 0.0 1.9 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase AAA_22 PF13401.1 AIN97527.1 - 0.026 14.6 0.0 0.057 13.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain DUF815 PF05673.8 AIN97527.1 - 0.05 12.5 0.0 0.085 11.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) KAP_NTPase PF07693.9 AIN97527.1 - 0.057 12.3 0.0 0.089 11.7 0.0 1.3 1 0 0 1 1 1 0 KAP family P-loop domain AAA_3 PF07726.6 AIN97527.1 - 0.076 12.6 0.1 0.5 9.9 0.0 2.2 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) NACHT PF05729.7 AIN97527.1 - 0.1 12.2 0.0 0.28 10.8 0.0 1.7 1 0 0 1 1 1 0 NACHT domain UPF0079 PF02367.12 AIN97527.1 - 0.12 12.0 0.0 0.27 10.8 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 eIF-5_eIF-2B PF01873.12 AIN97528.1 - 6.9e-32 109.7 0.1 1.2e-31 108.9 0.0 1.4 1 0 0 1 1 1 1 Domain found in IF2B/IF5 W2 PF02020.13 AIN97528.1 - 6.2e-05 22.8 1.2 0.00011 22.0 0.1 2.1 2 1 0 2 2 2 1 eIF4-gamma/eIF5/eIF2-epsilon FYDLN_acid PF09538.5 AIN97528.1 - 8.4 7.0 9.3 1.6e+02 2.9 6.5 2.5 1 1 0 1 1 1 0 Protein of unknown function (FYDLN_acid) RNA_pol_Rpb1_5 PF04998.12 AIN97529.1 - 3.4e-81 272.5 0.0 7.2e-81 271.4 0.0 1.5 1 1 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.15 AIN97529.1 - 1.2e-61 207.4 0.0 2.4e-61 206.5 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_1 PF04997.7 AIN97529.1 - 2.4e-56 191.4 0.0 3.6e-56 190.8 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_3 PF04983.13 AIN97529.1 - 8.5e-32 110.0 0.0 1.8e-31 109.0 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.12 AIN97529.1 - 2.2e-31 107.7 0.0 5.5e-31 106.5 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 COG6 PF06419.6 AIN97530.1 - 7.9e-41 139.8 0.1 1.2e-37 129.3 0.0 2.7 3 0 0 3 3 3 2 Conserved oligomeric complex COG6 IgG_binding_B PF01378.12 AIN97531.1 - 0.073 12.8 0.2 0.17 11.7 0.1 1.6 1 0 0 1 1 1 0 B domain PNP_UDP_1 PF01048.15 AIN97532.1 - 0.00096 18.1 0.4 0.0025 16.8 0.1 1.8 2 0 0 2 2 2 1 Phosphorylase superfamily EzrA PF06160.7 AIN97534.1 - 0.0071 14.5 4.4 0.015 13.5 0.0 2.1 2 0 0 2 2 2 1 Septation ring formation regulator, EzrA HrpB7 PF09486.5 AIN97534.1 - 0.049 13.5 13.0 0.09 12.7 5.2 2.9 2 1 1 3 3 3 0 Bacterial type III secretion protein (HrpB7) GAS PF13851.1 AIN97534.1 - 0.075 12.2 10.9 0.056 12.6 2.2 2.7 2 1 0 2 2 2 0 Growth-arrest specific micro-tubule binding DUF4140 PF13600.1 AIN97534.1 - 1.1 9.7 10.7 2.6 8.5 0.7 3.0 2 1 1 3 3 3 0 N-terminal domain of unknown function (DUF4140) COG2 PF06148.6 AIN97534.1 - 1.8 8.4 5.0 6.6 6.6 0.4 3.1 2 1 1 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 FUSC PF04632.7 AIN97536.1 - 0.021 13.2 2.7 0.1 11.0 0.1 2.0 2 0 0 2 2 2 0 Fusaric acid resistance protein family Ribosomal_S25 PF03297.10 AIN97537.1 - 2.8e-43 146.2 4.0 3.2e-43 146.0 2.7 1.0 1 0 0 1 1 1 1 S25 ribosomal protein DUF3516 PF12029.3 AIN97537.1 - 0.083 11.6 0.3 0.084 11.6 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3516) Tnp_P_element PF12017.3 AIN97538.1 - 0.086 12.0 0.0 0.14 11.3 0.0 1.2 1 0 0 1 1 1 0 Transposase protein HlyD PF00529.15 AIN97539.1 - 0.1 11.8 8.4 0.27 10.5 5.8 1.7 1 0 0 1 1 1 0 HlyD family secretion protein WD40 PF00400.27 AIN97540.1 - 2.2e-53 176.3 20.0 3.1e-08 33.1 0.0 7.7 7 0 0 7 7 7 7 WD domain, G-beta repeat DUF3312 PF11768.3 AIN97540.1 - 0.26 9.4 0.0 0.43 8.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3312) Ion_trans PF00520.26 AIN97541.1 - 2.8e-94 313.9 107.6 2.8e-32 111.5 11.2 4.9 5 0 0 5 5 5 4 Ion transport protein HEAT PF02985.17 AIN97542.1 - 6e-15 53.9 1.2 1.1 9.5 0.0 9.3 9 1 0 9 9 9 4 HEAT repeat HEAT_2 PF13646.1 AIN97542.1 - 1.5e-13 50.8 9.3 3.3e-05 24.1 0.1 6.6 6 1 1 7 7 7 3 HEAT repeats HEAT_EZ PF13513.1 AIN97542.1 - 1.1e-11 44.7 10.1 0.00026 21.3 0.1 8.1 6 2 4 10 10 10 4 HEAT-like repeat IBN_N PF03810.14 AIN97542.1 - 2.5e-10 40.1 0.5 2.3e-09 37.0 0.0 2.9 3 0 0 3 3 3 1 Importin-beta N-terminal domain Arm PF00514.18 AIN97542.1 - 1.1e-09 37.6 1.7 0.077 12.8 0.1 6.1 6 0 0 6 6 6 3 Armadillo/beta-catenin-like repeat Vac14_Fab1_bd PF12755.2 AIN97542.1 - 4e-06 27.1 4.2 0.83 10.0 0.0 5.8 4 3 1 5 5 5 3 Vacuolar 14 Fab1-binding region MMS19_C PF12460.3 AIN97542.1 - 1.3e-05 24.1 0.5 0.23 10.1 0.0 4.0 3 1 0 3 3 3 2 RNAPII transcription regulator C-terminal CLASP_N PF12348.3 AIN97542.1 - 0.0017 17.7 1.8 0.035 13.4 0.0 3.5 4 1 1 5 5 5 1 CLASP N terminal DUF3385 PF11865.3 AIN97542.1 - 0.0046 16.9 2.9 3 7.7 0.1 4.8 4 2 1 5 5 5 1 Domain of unknown function (DUF3385) Telomere_reg-2 PF10193.4 AIN97542.1 - 0.039 14.2 3.9 0.92 9.7 0.0 3.9 4 0 0 4 4 4 0 Telomere length regulation protein Glycos_transf_2 PF00535.21 AIN97543.1 - 0.0021 17.7 0.0 0.0048 16.5 0.0 1.6 2 0 0 2 2 2 1 Glycosyl transferase family 2 DUF2664 PF10867.3 AIN97545.1 - 1.2 9.8 3.8 3.9 8.1 0.1 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2664) SNAP PF14938.1 AIN97547.1 - 9.1e-06 25.0 17.7 0.00069 18.8 5.0 3.1 2 1 1 3 3 3 2 Soluble NSF attachment protein, SNAP TPR_12 PF13424.1 AIN97547.1 - 3.8e-05 23.5 1.4 1.3 9.0 0.0 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.12 AIN97547.1 - 0.00072 19.2 4.6 0.058 13.3 0.8 4.2 2 1 2 4 4 4 1 Tetratricopeptide repeat TPR_16 PF13432.1 AIN97547.1 - 0.0033 18.0 6.3 4 8.2 0.4 4.4 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.1 AIN97547.1 - 0.025 14.3 0.5 0.47 10.3 0.1 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.23 AIN97547.1 - 0.05 13.2 1.5 5.5 6.7 0.0 3.3 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.1 AIN97547.1 - 0.11 13.1 6.2 3.6 8.5 0.2 4.4 4 1 1 5 5 5 0 Tetratricopeptide repeat DUF725 PF05267.7 AIN97547.1 - 0.96 9.3 4.7 1.6 8.6 1.2 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF725) LRR_4 PF12799.2 AIN97548.1 - 1.1e-14 53.6 8.2 0.00032 20.2 0.0 6.4 4 1 2 6 6 6 6 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 AIN97548.1 - 0.00024 20.7 17.6 0.23 11.2 0.1 6.0 2 1 6 8 8 8 6 Leucine rich repeat GTP_EFTU PF00009.22 AIN97550.1 - 8e-43 146.0 0.2 1.2e-42 145.4 0.1 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain LepA_C PF06421.7 AIN97550.1 - 8.4e-29 99.6 1.3 1.5e-28 98.7 0.9 1.4 1 0 0 1 1 1 1 GTP-binding protein LepA C-terminus EFG_C PF00679.19 AIN97550.1 - 3.4e-14 52.4 0.3 7.6e-14 51.3 0.0 1.8 2 0 0 2 2 2 1 Elongation factor G C-terminus MMR_HSR1 PF01926.18 AIN97550.1 - 6e-05 22.9 0.0 0.00017 21.4 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase Ras PF00071.17 AIN97550.1 - 0.00029 20.2 0.0 0.00063 19.1 0.0 1.5 1 0 0 1 1 1 1 Ras family PduV-EutP PF10662.4 AIN97550.1 - 0.0013 18.2 0.0 0.0093 15.4 0.0 2.1 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation Septin PF00735.13 AIN97550.1 - 0.032 13.2 0.1 0.53 9.2 0.0 2.3 2 0 0 2 2 2 0 Septin GTP_EFTU_D2 PF03144.20 AIN97550.1 - 0.048 13.7 0.0 0.11 12.5 0.0 1.7 1 0 0 1 1 1 0 Elongation factor Tu domain 2 DUF677 PF05055.7 AIN97551.1 - 0.00027 19.7 2.1 0.00032 19.4 1.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF677) Troponin PF00992.15 AIN97551.1 - 0.0057 16.7 13.6 0.0082 16.2 9.4 1.3 1 0 0 1 1 1 1 Troponin Uso1_p115_C PF04871.8 AIN97551.1 - 0.01 15.7 7.7 0.012 15.4 5.3 1.2 1 0 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region YscO PF07321.7 AIN97551.1 - 0.011 15.5 7.3 0.014 15.2 5.0 1.3 1 0 0 1 1 1 0 Type III secretion protein YscO Val_tRNA-synt_C PF10458.4 AIN97551.1 - 0.017 15.1 6.4 1 9.4 1.4 3.5 3 1 1 4 4 4 0 Valyl tRNA synthetase tRNA binding arm Metal_resist PF13801.1 AIN97551.1 - 0.02 14.8 0.3 0.034 14.1 0.2 1.4 1 0 0 1 1 1 0 Heavy-metal resistance Prefoldin_2 PF01920.15 AIN97551.1 - 0.03 14.0 9.1 0.038 13.7 5.8 1.6 1 1 0 1 1 1 0 Prefoldin subunit Mn_catalase PF05067.7 AIN97551.1 - 0.045 12.4 0.5 0.056 12.1 0.3 1.2 1 0 0 1 1 1 0 Manganese containing catalase Caudo_TAP PF02413.12 AIN97551.1 - 0.054 13.6 3.0 0.069 13.3 2.0 1.1 1 0 0 1 1 1 0 Caudovirales tail fibre assembly protein DUF3450 PF11932.3 AIN97551.1 - 0.073 12.3 3.2 0.089 12.0 2.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) DUF4446 PF14584.1 AIN97551.1 - 0.077 12.8 6.4 0.072 12.9 3.7 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF4446) DNA_topoisoIV PF00521.15 AIN97551.1 - 0.087 11.6 3.1 0.092 11.5 2.1 1.0 1 0 0 1 1 1 0 DNA gyrase/topoisomerase IV, subunit A Ax_dynein_light PF10211.4 AIN97551.1 - 0.1 12.3 9.7 0.13 12.1 6.7 1.1 1 0 0 1 1 1 0 Axonemal dynein light chain TroA PF01297.12 AIN97551.1 - 0.12 11.5 1.2 0.18 11.0 0.8 1.2 1 0 0 1 1 1 0 Periplasmic solute binding protein family V_ATPase_I PF01496.14 AIN97551.1 - 0.14 9.9 5.4 0.14 9.9 3.8 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family NPV_P10 PF05531.7 AIN97551.1 - 0.18 12.0 0.8 0.33 11.2 0.6 1.4 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein DUF948 PF06103.6 AIN97551.1 - 0.19 11.6 1.1 0.3 10.9 0.8 1.4 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) SlyX PF04102.7 AIN97551.1 - 0.2 12.0 5.9 0.47 10.8 1.4 2.2 1 1 1 2 2 2 0 SlyX PRP1_N PF06424.7 AIN97551.1 - 0.22 11.8 6.3 0.27 11.5 4.4 1.1 1 0 0 1 1 1 0 PRP1 splicing factor, N-terminal Synaptobrevin PF00957.16 AIN97551.1 - 0.23 11.0 4.2 0.34 10.5 2.9 1.3 1 0 0 1 1 1 0 Synaptobrevin Atg14 PF10186.4 AIN97551.1 - 0.36 9.7 5.6 0.35 9.7 3.9 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DUF2533 PF10752.4 AIN97551.1 - 0.37 11.1 5.5 8.8 6.7 2.1 2.4 1 1 0 2 2 2 0 Protein of unknown function (DUF2533) Gon7 PF08738.5 AIN97551.1 - 0.41 10.6 3.6 0.33 10.9 0.4 2.1 2 0 0 2 2 2 0 Gon7 family EssA PF10661.4 AIN97551.1 - 0.51 10.0 10.3 0.47 10.1 6.2 1.5 1 1 0 1 1 1 0 WXG100 protein secretion system (Wss), protein EssA IncA PF04156.9 AIN97551.1 - 0.52 9.8 9.0 0.74 9.3 6.2 1.2 1 0 0 1 1 1 0 IncA protein Seryl_tRNA_N PF02403.17 AIN97551.1 - 0.56 10.2 11.3 1.1 9.3 4.6 2.0 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain DUF1664 PF07889.7 AIN97551.1 - 0.71 9.6 4.0 1 9.2 2.5 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) DUF3144 PF11342.3 AIN97551.1 - 0.82 9.7 2.9 2.1 8.4 0.3 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3144) TSC22 PF01166.13 AIN97551.1 - 0.86 9.6 10.8 1.6 8.7 1.7 2.5 2 1 1 3 3 2 0 TSC-22/dip/bun family Fib_alpha PF08702.5 AIN97551.1 - 1.5 8.8 6.5 1.7 8.7 3.9 1.5 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family DUF904 PF06005.7 AIN97551.1 - 2.2 8.6 14.2 1.5 9.1 8.8 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF904) Rabaptin PF03528.10 AIN97551.1 - 2.9 7.8 11.7 4.4 7.2 8.1 1.4 1 1 0 1 1 1 0 Rabaptin APG6 PF04111.7 AIN97551.1 - 3.1 6.7 10.3 3.6 6.5 7.2 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 Pox_A_type_inc PF04508.7 AIN97551.1 - 5.8 6.9 12.2 6 6.9 0.7 3.5 3 2 0 3 3 3 0 Viral A-type inclusion protein repeat Bap31 PF05529.7 AIN97551.1 - 6.2 6.2 9.0 9.4 5.6 6.2 1.5 1 1 0 1 1 1 0 B-cell receptor-associated protein 31-like DUF1202 PF06717.6 AIN97553.1 - 0.02 14.1 6.0 0.033 13.4 4.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1202) UPF0242 PF06785.6 AIN97553.1 - 3.6 6.1 10.9 5.8 5.4 7.6 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) NMO PF03060.10 AIN97554.1 - 3e-60 204.0 2.2 2e-59 201.3 1.5 1.9 1 1 0 1 1 1 1 Nitronate monooxygenase FMN_dh PF01070.13 AIN97554.1 - 1.8e-08 33.6 0.3 3e-08 32.9 0.2 1.3 1 0 0 1 1 1 1 FMN-dependent dehydrogenase DHO_dh PF01180.16 AIN97554.1 - 6.2e-07 28.6 0.1 1.9e-06 27.0 0.1 1.7 2 0 0 2 2 2 1 Dihydroorotate dehydrogenase Glu_synthase PF01645.12 AIN97554.1 - 0.00045 19.2 0.4 0.00074 18.5 0.3 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.20 AIN97554.1 - 0.00097 18.1 0.3 0.0019 17.1 0.2 1.4 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain ThiG PF05690.9 AIN97554.1 - 0.0038 16.3 0.5 0.0065 15.5 0.3 1.3 1 0 0 1 1 1 1 Thiazole biosynthesis protein ThiG Dus PF01207.12 AIN97554.1 - 0.012 14.5 0.1 0.044 12.6 0.0 1.9 2 0 0 2 2 2 0 Dihydrouridine synthase (Dus) His_biosynth PF00977.16 AIN97554.1 - 0.064 12.5 0.1 0.1 11.8 0.1 1.3 1 0 0 1 1 1 0 Histidine biosynthesis protein NanE PF04131.9 AIN97554.1 - 0.088 11.7 0.1 0.14 11.0 0.1 1.3 1 0 0 1 1 1 0 Putative N-acetylmannosamine-6-phosphate epimerase Sec20 PF03908.8 AIN97556.1 - 0.018 14.7 1.4 0.053 13.2 1.0 1.8 1 0 0 1 1 1 0 Sec20 DUF1759 PF03564.10 AIN97556.1 - 0.07 12.9 3.0 0.056 13.2 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1759) Pantoate_transf PF02548.10 AIN97557.1 - 0.15 11.1 2.8 0.52 9.3 0.5 2.2 2 0 0 2 2 2 0 Ketopantoate hydroxymethyltransferase LRR_8 PF13855.1 AIN97558.1 - 0.0014 18.3 1.0 0.064 13.0 0.0 3.2 3 0 0 3 3 3 1 Leucine rich repeat LRR_4 PF12799.2 AIN97558.1 - 0.0048 16.5 4.3 4 7.1 0.1 4.0 4 1 2 6 6 6 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 AIN97558.1 - 0.28 11.3 4.4 49 4.5 0.1 5.2 5 0 0 5 5 5 0 Leucine Rich Repeat JAB PF01398.16 AIN97559.1 - 1.1e-29 102.4 0.0 2.4e-29 101.3 0.0 1.6 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Prok-JAB PF14464.1 AIN97559.1 - 4.2e-10 39.1 0.0 6.8e-10 38.4 0.0 1.5 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain MitMem_reg PF13012.1 AIN97559.1 - 6e-08 32.7 0.5 1.1e-07 31.9 0.4 1.4 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function PSD3 PF07626.6 AIN97559.1 - 0.045 13.7 0.0 0.11 12.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1587) ABC_tran PF00005.22 AIN97561.1 - 6.2e-39 133.4 0.0 2.3e-22 79.7 0.0 2.7 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 AIN97561.1 - 4.7e-30 104.9 21.3 6.4e-16 58.5 6.0 3.4 3 0 0 3 3 3 3 ABC transporter transmembrane region SMC_N PF02463.14 AIN97561.1 - 3.8e-08 32.8 0.4 0.0032 16.7 0.0 4.1 3 1 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 AIN97561.1 - 7e-07 29.4 0.0 0.26 11.2 0.0 4.0 4 0 0 4 4 4 2 AAA domain AAA_25 PF13481.1 AIN97561.1 - 3.3e-05 23.3 0.0 0.012 15.0 0.0 2.7 2 0 0 2 2 2 1 AAA domain DUF258 PF03193.11 AIN97561.1 - 3.6e-05 22.9 0.0 0.068 12.3 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 MMR_HSR1 PF01926.18 AIN97561.1 - 4.2e-05 23.4 0.0 0.018 14.9 0.0 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_29 PF13555.1 AIN97561.1 - 6e-05 22.5 0.0 0.11 12.0 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.1 AIN97561.1 - 0.00026 21.0 1.9 0.22 11.4 0.0 3.5 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 AIN97561.1 - 0.013 15.6 0.0 0.49 10.5 0.0 2.9 3 0 0 3 3 2 0 AAA domain AIG1 PF04548.11 AIN97561.1 - 0.014 14.5 0.1 1.1 8.3 0.1 2.4 2 0 0 2 2 2 0 AIG1 family AAA_23 PF13476.1 AIN97561.1 - 0.015 15.6 0.1 4.3 7.5 0.0 2.3 2 0 0 2 2 2 0 AAA domain Dynamin_N PF00350.18 AIN97561.1 - 0.016 15.0 0.1 1.1 9.0 0.1 2.5 2 0 0 2 2 2 0 Dynamin family AAA PF00004.24 AIN97561.1 - 0.018 15.2 0.0 2.7 8.1 0.0 3.2 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) Miro PF08477.8 AIN97561.1 - 0.024 15.1 0.0 11 6.5 0.0 2.6 2 0 0 2 2 2 0 Miro-like protein RNA_helicase PF00910.17 AIN97561.1 - 0.055 13.6 0.1 3.8 7.7 0.0 3.0 3 0 0 3 3 3 0 RNA helicase Arch_ATPase PF01637.13 AIN97561.1 - 0.059 13.0 0.0 0.3 10.7 0.0 2.1 2 0 0 2 2 2 0 Archaeal ATPase AAA_14 PF13173.1 AIN97561.1 - 0.33 10.8 0.0 0.96 9.3 0.0 1.8 1 0 0 1 1 1 0 AAA domain Adeno_IVa2 PF02456.10 AIN97561.1 - 0.4 9.2 0.1 1.5 7.4 0.0 1.8 2 0 0 2 2 2 0 Adenovirus IVa2 protein Cep57_MT_bd PF06657.8 AIN97562.1 - 0.017 15.0 4.0 0.017 15.0 2.8 4.2 4 1 0 4 4 4 0 Centrosome microtubule-binding domain of Cep57 CENP-F_leu_zip PF10473.4 AIN97562.1 - 0.071 12.9 36.5 0.18 11.6 1.5 4.6 3 1 1 4 4 4 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 FtsA PF14450.1 AIN97562.1 - 0.18 11.6 0.6 0.68 9.7 0.1 2.1 2 0 0 2 2 2 0 Cell division protein FtsA Herpes_UL6 PF01763.11 AIN97562.1 - 2.1 6.3 9.1 3.4 5.7 0.5 2.9 3 0 0 3 3 3 0 Herpesvirus UL6 like Prominin PF05478.6 AIN97562.1 - 3.2 5.1 11.1 2.5 5.5 5.0 2.0 2 0 0 2 2 2 0 Prominin V_ATPase_I PF01496.14 AIN97562.1 - 3.3 5.4 8.8 19 2.9 0.0 2.4 2 1 0 2 2 2 0 V-type ATPase 116kDa subunit family DUF769 PF05590.6 AIN97563.1 - 0.0052 16.0 0.2 0.006 15.8 0.1 1.1 1 0 0 1 1 1 1 Xylella fastidiosa protein of unknown function (DUF769) Cast PF10174.4 AIN97563.1 - 0.0058 14.7 6.9 0.007 14.4 4.8 1.1 1 0 0 1 1 1 1 RIM-binding protein of the cytomatrix active zone DUF4164 PF13747.1 AIN97563.1 - 0.074 13.1 9.5 0.55 10.4 0.5 2.8 1 1 2 3 3 3 0 Domain of unknown function (DUF4164) T2SM PF04612.7 AIN97563.1 - 0.11 12.2 1.9 1.1 9.0 1.9 1.8 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein M CENP-F_leu_zip PF10473.4 AIN97563.1 - 0.14 12.0 15.7 4.1 7.2 10.9 2.4 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 KaiC PF06745.8 AIN97563.1 - 0.17 10.9 0.8 0.22 10.5 0.5 1.3 1 0 0 1 1 1 0 KaiC Rab5-bind PF09311.6 AIN97563.1 - 0.71 9.7 7.8 1.5 8.7 5.5 1.4 1 1 0 1 1 1 0 Rabaptin-like protein TMF_TATA_bd PF12325.3 AIN97563.1 - 1.1 9.0 12.2 21 4.8 6.7 2.1 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding bZIP_1 PF00170.16 AIN97563.1 - 4.1 7.4 9.0 6.2 6.8 1.0 3.1 3 0 0 3 3 3 0 bZIP transcription factor GAS PF13851.1 AIN97563.1 - 5 6.2 10.6 4.2 6.5 4.0 2.2 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding BRE1 PF08647.6 AIN97563.1 - 7.9 6.5 9.2 9 6.3 5.1 2.0 1 1 1 2 2 2 0 BRE1 E3 ubiquitin ligase EspA PF03433.8 AIN97564.1 - 0.13 11.7 7.9 0.25 10.7 0.0 3.8 4 0 0 4 4 4 0 EspA-like secreted protein DUF972 PF06156.8 AIN97564.1 - 5 7.5 21.6 0.11 12.8 2.4 5.0 5 0 0 5 5 5 0 Protein of unknown function (DUF972) DUF2039 PF10217.4 AIN97565.1 - 1e-26 92.7 20.9 1.5e-26 92.1 14.5 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2039) Tankyrase_bdg_C PF15327.1 AIN97565.1 - 0.037 14.2 1.0 0.052 13.7 0.7 1.3 1 0 0 1 1 1 0 Tankyrase binding protein C terminal domain Cript PF10235.4 AIN97565.1 - 2.6 8.4 15.4 6.6 7.1 10.7 1.8 1 1 0 1 1 1 0 Microtubule-associated protein CRIPT Tcp10_C PF07202.8 AIN97567.1 - 0.0048 16.4 0.3 0.01 15.4 0.2 1.5 1 0 0 1 1 1 1 T-complex protein 10 C-terminus Sod_Fe_C PF02777.13 AIN97567.1 - 0.015 15.1 0.0 0.043 13.6 0.0 1.7 1 0 0 1 1 1 0 Iron/manganese superoxide dismutases, C-terminal domain SpoIIE PF07228.7 AIN97568.1 - 1.6e-09 37.7 0.0 2e-09 37.4 0.0 1.1 1 0 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) PP2C_2 PF13672.1 AIN97568.1 - 0.0012 18.2 0.0 0.0018 17.7 0.0 1.4 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C PF00481.16 AIN97568.1 - 0.035 13.4 0.0 0.073 12.4 0.0 1.5 2 0 0 2 2 2 0 Protein phosphatase 2C CBF PF03914.12 AIN97569.1 - 7.6e-37 126.2 0.1 1.3e-36 125.5 0.1 1.4 1 0 0 1 1 1 1 CBF/Mak21 family NAD_binding_10 PF13460.1 AIN97571.1 - 1.3e-06 28.6 0.1 8.1e-06 25.9 0.1 2.2 2 0 0 2 2 2 1 NADH(P)-binding NmrA PF05368.8 AIN97571.1 - 0.0001 21.6 0.3 0.00029 20.1 0.1 1.7 2 0 0 2 2 2 1 NmrA-like family NAD_binding_4 PF07993.7 AIN97571.1 - 0.0058 15.5 0.3 0.0094 14.9 0.2 1.3 1 0 0 1 1 1 1 Male sterility protein Saccharop_dh PF03435.13 AIN97571.1 - 0.022 13.7 0.0 0.032 13.2 0.0 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase Epimerase PF01370.16 AIN97571.1 - 0.022 14.1 0.1 0.24 10.8 0.0 2.2 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family adh_short PF00106.20 AIN97571.1 - 0.027 14.4 0.1 0.053 13.4 0.1 1.5 1 0 0 1 1 1 0 short chain dehydrogenase BTV_NS2 PF04514.7 AIN97572.1 - 0.1 11.4 2.6 0.12 11.2 1.8 1.1 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 Metallophos PF00149.23 AIN97573.1 - 3.4e-36 124.5 0.3 4.6e-36 124.0 0.2 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos PF00149.23 AIN97574.1 - 8.8e-37 126.4 0.4 1.1e-36 126.1 0.3 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos PF00149.23 AIN97575.1 - 5.1e-36 123.9 0.4 7e-36 123.5 0.3 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Pcc1 PF09341.5 AIN97576.1 - 9.6e-15 54.3 0.1 1.3e-14 54.0 0.1 1.2 1 0 0 1 1 1 1 Transcription factor Pcc1 EF1_GNE PF00736.14 AIN97577.1 - 3.6e-30 103.4 1.6 5.8e-30 102.8 1.1 1.3 1 0 0 1 1 1 1 EF-1 guanine nucleotide exchange domain DUF3275 PF11679.3 AIN97577.1 - 0.013 15.1 1.8 0.019 14.6 1.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3275) Mrr_cat PF04471.7 AIN97577.1 - 0.087 12.6 0.2 3.8 7.3 0.1 2.4 1 1 1 2 2 2 0 Restriction endonuclease EF1_GNE PF00736.14 AIN97579.1 - 1.2e-29 101.8 1.6 1.9e-29 101.1 1.1 1.3 1 0 0 1 1 1 1 EF-1 guanine nucleotide exchange domain Metallophos PF00149.23 AIN97580.1 - 1e-34 119.6 0.0 1.2e-34 119.4 0.0 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 AIN97580.1 - 0.034 14.0 0.0 0.048 13.5 0.0 1.2 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain Ribosomal_L13 PF00572.13 AIN97581.1 - 2.7e-22 79.1 1.1 3.1e-22 78.9 0.1 1.6 2 0 0 2 2 2 1 Ribosomal protein L13 DUF4455 PF14643.1 AIN97581.1 - 0.066 11.8 2.6 0.088 11.4 1.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4455) Cro PF09048.5 AIN97581.1 - 0.31 10.6 1.9 1.2 8.8 0.1 2.2 2 0 0 2 2 2 0 Cro Pox_Ag35 PF03286.9 AIN97582.1 - 0.39 10.2 5.9 0.68 9.4 4.1 1.3 1 0 0 1 1 1 0 Pox virus Ag35 surface protein RNA_pol_Rpb6 PF01192.17 AIN97584.1 - 1.1e-19 69.9 0.6 2e-19 69.0 0.4 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb6 UQ_con PF00179.21 AIN97585.1 - 4.3e-18 65.1 0.0 6.1e-18 64.6 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 AIN97585.1 - 0.092 12.6 0.0 0.16 11.9 0.0 1.3 1 0 0 1 1 1 0 RWD domain Med3 PF11593.3 AIN97585.1 - 0.23 10.6 8.3 0.27 10.4 5.8 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal DUF2890 PF11081.3 AIN97585.1 - 1.1 9.2 7.0 0.78 9.7 3.8 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2890) Mif2_N PF15624.1 AIN97585.1 - 3.2 8.3 6.4 0.9 10.1 2.3 1.6 2 0 0 2 2 2 0 Kinetochore CENP-C fungal homologue, Mif2, N-terminal YlbD_coat PF14071.1 AIN97587.1 - 0.29 11.1 0.6 15 5.6 0.1 2.6 2 1 0 2 2 2 0 Putative coat protein SR-25 PF10500.4 AIN97587.1 - 2.6 7.4 11.9 5.9 6.2 8.3 1.6 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Pkinase PF00069.20 AIN97589.1 - 3.3e-39 134.6 0.0 2.2e-29 102.4 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 AIN97589.1 - 1.2e-19 70.4 0.0 5.7e-14 51.8 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Amastin PF07344.6 AIN97590.1 - 2.2e-53 180.0 10.0 2.6e-53 179.8 6.9 1.0 1 0 0 1 1 1 1 Amastin surface glycoprotein Claudin_2 PF13903.1 AIN97590.1 - 0.0044 16.7 14.6 0.0044 16.7 10.1 1.8 1 1 1 2 2 2 1 PMP-22/EMP/MP20/Claudin tight junction DUF4293 PF14126.1 AIN97590.1 - 0.13 12.1 7.0 0.36 10.7 4.9 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4293) COX6C PF02937.10 AIN97590.1 - 0.21 11.5 1.0 0.32 10.9 0.1 1.8 2 0 0 2 2 2 0 Cytochrome c oxidase subunit VIc DUF1469 PF07332.6 AIN97590.1 - 3.1 7.5 16.5 0.036 13.8 1.8 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF1469) DUF2157 PF09925.4 AIN97590.1 - 7.6 6.1 11.6 0.83 9.2 4.0 2.0 2 0 0 2 2 2 0 Predicted membrane protein (DUF2157) Amastin PF07344.6 AIN97591.1 - 3.9e-53 179.2 11.9 4.6e-53 178.9 8.3 1.1 1 0 0 1 1 1 1 Amastin surface glycoprotein PMP22_Claudin PF00822.15 AIN97591.1 - 1.8e-05 24.4 8.5 2.3e-05 24.1 5.9 1.2 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family Claudin_2 PF13903.1 AIN97591.1 - 3.3e-05 23.6 8.6 3.3e-05 23.6 6.0 1.9 1 1 1 2 2 2 1 PMP-22/EMP/MP20/Claudin tight junction DUF2708 PF10917.3 AIN97591.1 - 0.075 12.8 0.5 0.21 11.4 0.3 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2708) DUF3087 PF11286.3 AIN97591.1 - 3.6 6.7 5.2 0.47 9.6 0.6 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3087) UPF0114 PF03350.11 AIN97591.1 - 5.5 6.9 9.3 0.42 10.5 1.7 2.4 2 1 1 3 3 3 0 Uncharacterized protein family, UPF0114 Amastin PF07344.6 AIN97592.1 - 6.2e-43 146.0 11.1 7.4e-43 145.8 7.7 1.0 1 0 0 1 1 1 1 Amastin surface glycoprotein Claudin_2 PF13903.1 AIN97592.1 - 0.018 14.7 12.6 0.037 13.7 7.8 2.2 1 1 1 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction Myosin_head PF00063.16 AIN97593.1 - 2.6e-198 660.3 0.0 1e-197 658.3 0.0 1.9 1 1 0 1 1 1 1 Myosin head (motor domain) Myosin_TH1 PF06017.8 AIN97593.1 - 6.9e-10 38.5 0.0 0.00061 19.1 0.0 3.2 2 1 0 2 2 2 2 Myosin tail FYVE PF01363.16 AIN97593.1 - 0.00012 21.9 9.0 0.00031 20.5 6.3 1.6 1 0 0 1 1 1 1 FYVE zinc finger Zeta_toxin PF06414.7 AIN97593.1 - 0.0086 15.1 0.0 0.0086 15.1 0.0 2.4 2 0 0 2 2 2 1 Zeta toxin AAA_17 PF13207.1 AIN97593.1 - 0.017 15.9 2.4 0.12 13.2 0.0 3.4 3 0 0 3 3 3 0 AAA domain AAA_22 PF13401.1 AIN97593.1 - 0.022 14.9 0.0 0.063 13.4 0.0 1.8 1 0 0 1 1 1 0 AAA domain HTH_30 PF13556.1 AIN97594.1 - 0.032 13.8 0.3 0.12 12.0 0.2 2.0 1 0 0 1 1 1 0 PucR C-terminal helix-turn-helix domain N2227 PF07942.7 AIN97595.1 - 9.2e-95 316.6 0.0 1.2e-94 316.2 0.0 1.1 1 0 0 1 1 1 1 N2227-like protein Methyltransf_23 PF13489.1 AIN97595.1 - 0.025 14.3 0.0 0.049 13.3 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain EF-hand_8 PF13833.1 AIN97596.1 - 1e-08 34.6 0.1 1.7e-08 33.9 0.1 1.3 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_7 PF13499.1 AIN97596.1 - 3.6e-08 33.4 0.0 6.2e-08 32.6 0.0 1.3 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.27 AIN97596.1 - 3.2e-06 26.0 0.1 0.0011 18.0 0.1 2.7 2 1 1 3 3 3 2 EF hand EF-hand_5 PF13202.1 AIN97596.1 - 2e-05 23.7 1.6 0.00022 20.4 0.1 2.7 3 0 0 3 3 3 1 EF hand EF-hand_6 PF13405.1 AIN97596.1 - 9.3e-05 21.9 0.1 0.046 13.6 0.1 2.8 1 1 1 2 2 2 2 EF-hand domain FG-GAP PF01839.18 AIN97596.1 - 0.033 13.8 0.4 0.15 11.7 0.3 2.2 1 0 0 1 1 1 0 FG-GAP repeat EF-hand_4 PF12763.2 AIN97596.1 - 0.058 13.1 0.0 0.3 10.8 0.0 1.9 2 0 0 2 2 2 0 Cytoskeletal-regulatory complex EF hand UPRTase PF14681.1 AIN97597.1 - 3.9e-70 235.2 0.0 4.6e-70 235.0 0.0 1.0 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.22 AIN97597.1 - 9.2e-06 25.3 0.0 1.4e-05 24.7 0.0 1.4 1 0 0 1 1 1 1 Phosphoribosyl transferase domain TPR_11 PF13414.1 AIN97598.1 - 4.3e-21 74.3 1.2 5.3e-07 29.1 0.0 3.8 2 1 1 3 3 3 3 TPR repeat SET PF00856.23 AIN97598.1 - 1.4e-10 41.7 0.0 7.3e-10 39.3 0.0 2.3 2 1 0 2 2 2 1 SET domain TPR_2 PF07719.12 AIN97598.1 - 2.2e-09 36.4 7.8 0.00042 20.0 0.1 5.3 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_12 PF13424.1 AIN97598.1 - 3.7e-07 29.9 7.6 0.0033 17.3 0.1 4.1 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_1 PF00515.23 AIN97598.1 - 0.00039 19.8 11.5 0.0085 15.6 0.4 4.6 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.1 AIN97598.1 - 0.00068 20.0 6.3 0.044 14.4 0.0 5.0 4 2 0 4 4 4 1 Tetratricopeptide repeat TPR_8 PF13181.1 AIN97598.1 - 0.002 17.7 1.5 0.029 14.1 0.0 3.5 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_19 PF14559.1 AIN97598.1 - 0.0045 17.2 0.1 0.65 10.3 0.0 3.2 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_10 PF13374.1 AIN97598.1 - 0.084 12.8 1.0 2.9 7.9 0.0 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_17 PF13431.1 AIN97598.1 - 0.11 12.7 1.4 2 8.8 0.0 3.6 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_7 PF13176.1 AIN97598.1 - 0.15 11.9 3.5 8.8 6.4 0.1 3.9 4 0 0 4 4 3 0 Tetratricopeptide repeat TPR_16 PF13432.1 AIN97598.1 - 1.6 9.4 9.0 44 4.9 0.4 4.8 5 1 0 5 5 4 0 Tetratricopeptide repeat TPR_6 PF13174.1 AIN97598.1 - 5.7 7.6 5.9 27 5.4 0.1 4.1 4 0 0 4 4 3 0 Tetratricopeptide repeat Peptidase_M41 PF01434.13 AIN97600.1 - 8.7e-45 152.8 0.0 1.5e-44 151.9 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.24 AIN97600.1 - 4.1e-39 133.8 0.0 7.3e-39 132.9 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.1 AIN97600.1 - 6.5e-05 22.4 0.1 0.17 11.2 0.0 2.5 1 1 1 2 2 2 2 AAA domain AAA_19 PF13245.1 AIN97600.1 - 0.00015 21.4 0.3 0.0027 17.4 0.1 2.7 2 0 0 2 2 2 1 Part of AAA domain AAA_2 PF07724.9 AIN97600.1 - 0.00028 20.8 0.0 0.00062 19.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.1 AIN97600.1 - 0.00043 20.3 0.3 0.12 12.3 0.1 3.2 2 1 1 3 3 3 1 AAA ATPase domain RuvB_N PF05496.7 AIN97600.1 - 0.00049 19.2 0.0 0.0011 18.0 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 AIN97600.1 - 0.00069 19.7 0.0 0.015 15.4 0.0 2.6 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 AIN97600.1 - 0.0011 19.7 0.0 0.0031 18.3 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.1 AIN97600.1 - 0.0017 18.2 0.0 0.0032 17.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain TIP49 PF06068.8 AIN97600.1 - 0.0028 16.4 0.0 0.0046 15.7 0.0 1.2 1 0 0 1 1 1 1 TIP49 C-terminus IstB_IS21 PF01695.12 AIN97600.1 - 0.0076 15.6 0.0 0.014 14.7 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_5 PF07728.9 AIN97600.1 - 0.0079 15.9 3.0 0.15 11.7 0.2 3.8 4 1 0 4 4 4 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.16 AIN97600.1 - 0.051 12.7 0.1 0.17 11.0 0.1 1.8 1 1 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_18 PF13238.1 AIN97600.1 - 0.13 12.5 0.0 0.77 10.0 0.0 2.3 3 0 0 3 3 3 0 AAA domain NB-ARC PF00931.17 AIN97600.1 - 0.23 10.2 0.2 4.2 6.1 0.0 2.1 1 1 1 2 2 2 0 NB-ARC domain Lipase_3 PF01764.20 AIN97601.1 - 5e-08 32.6 0.0 1.1e-07 31.5 0.0 1.6 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_5 PF12695.2 AIN97601.1 - 1.5e-05 24.7 0.0 4.1e-05 23.3 0.0 1.8 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 AIN97601.1 - 5e-05 23.2 0.6 5e-05 23.2 0.4 3.5 2 1 1 3 3 3 1 Alpha/beta hydrolase family DUF2974 PF11187.3 AIN97601.1 - 0.00022 20.6 0.5 0.001 18.4 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF2974) Thioesterase PF00975.15 AIN97601.1 - 0.018 15.2 0.0 0.034 14.3 0.0 1.4 1 0 0 1 1 1 0 Thioesterase domain PGAP1 PF07819.8 AIN97601.1 - 0.058 12.9 0.0 0.12 11.9 0.0 1.4 1 0 0 1 1 1 0 PGAP1-like protein UCH_1 PF13423.1 AIN97601.1 - 0.094 12.1 0.7 0.16 11.3 0.5 1.2 1 0 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase AXE1 PF05448.7 AIN97601.1 - 0.11 10.9 0.0 0.25 9.8 0.0 1.5 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) Amastin PF07344.6 AIN97602.1 - 2.3e-49 166.9 9.7 2.8e-49 166.6 6.8 1.1 1 0 0 1 1 1 1 Amastin surface glycoprotein Claudin_2 PF13903.1 AIN97602.1 - 1.4 8.6 19.3 0.087 12.5 8.6 2.0 1 1 1 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction DUF3719 PF12516.3 AIN97603.1 - 0.32 10.6 1.5 0.84 9.2 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3719) Kinesin PF00225.18 AIN97604.1 - 3.6e-83 279.0 0.0 5.2e-83 278.5 0.0 1.2 1 0 0 1 1 1 1 Kinesin motor domain Helicase_C PF00271.26 AIN97605.1 - 1.2e-05 25.0 0.0 0.00011 21.9 0.0 2.5 3 0 0 3 3 3 1 Helicase conserved C-terminal domain DEAD PF00270.24 AIN97605.1 - 8.4e-05 22.1 0.0 0.00017 21.1 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_19 PF13245.1 AIN97605.1 - 0.032 13.9 1.3 0.062 13.0 0.1 2.1 2 0 0 2 2 2 0 Part of AAA domain UQ_con PF00179.21 AIN97606.1 - 1.4e-15 56.9 0.0 1.5e-15 56.8 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 AIN97606.1 - 0.076 12.7 0.1 0.39 10.4 0.0 1.9 1 1 0 1 1 1 0 Prokaryotic E2 family B Acyltransferase PF01553.16 AIN97607.1 - 9.9e-18 63.8 0.0 2e-17 62.8 0.0 1.5 1 0 0 1 1 1 1 Acyltransferase GSK-3_bind PF05350.7 AIN97608.1 - 0.035 13.5 0.0 0.075 12.4 0.0 1.5 1 0 0 1 1 1 0 Glycogen synthase kinase-3 binding PNRC PF15365.1 AIN97608.1 - 1.4 9.0 7.4 0.13 12.3 1.7 1.8 2 0 0 2 2 2 0 Proline-rich nuclear receptor coactivator SBDS_C PF09377.5 AIN97609.1 - 2.3e-33 114.5 0.1 4.1e-33 113.7 0.1 1.4 1 0 0 1 1 1 1 SBDS protein C-terminal domain SBDS PF01172.13 AIN97609.1 - 5.1e-24 83.8 0.3 5.1e-24 83.8 0.2 2.2 2 0 0 2 2 2 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein DUF1042 PF06294.6 AIN97610.1 - 9.9e-33 112.9 0.0 1.7e-32 112.1 0.0 1.4 1 0 0 1 1 1 1 Domain of Unknown Function (DUF1042) CAMSAP_CH PF11971.3 AIN97610.1 - 1.4e-24 85.5 0.0 2.4e-24 84.7 0.0 1.4 1 0 0 1 1 1 1 CAMSAP CH domain CH PF00307.26 AIN97610.1 - 3.6e-05 23.7 0.0 6.1e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 Calponin homology (CH) domain TMF_DNA_bd PF12329.3 AIN97610.1 - 0.034 13.9 0.5 0.13 12.0 0.4 1.9 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding Mod_r PF07200.8 AIN97610.1 - 0.12 12.2 2.1 0.21 11.4 1.4 1.4 1 0 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein Dus PF01207.12 AIN97612.1 - 7.6e-53 179.3 0.1 7.4e-26 90.7 0.0 2.3 1 1 1 2 2 2 2 Dihydrouridine synthase (Dus) His_biosynth PF00977.16 AIN97612.1 - 1.7e-05 24.1 0.0 3.8e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 Histidine biosynthesis protein ThiG PF05690.9 AIN97612.1 - 0.0048 16.0 0.0 0.0079 15.3 0.0 1.3 1 0 0 1 1 1 1 Thiazole biosynthesis protein ThiG DUF849 PF05853.7 AIN97612.1 - 0.02 13.8 0.0 0.045 12.6 0.0 1.6 1 0 0 1 1 1 0 Prokaryotic protein of unknown function (DUF849) BMC PF00936.14 AIN97612.1 - 0.28 10.9 2.1 0.35 10.5 0.1 2.1 2 0 0 2 2 2 0 BMC domain DUF167 PF02594.11 AIN97614.1 - 2e-10 40.4 0.0 1.2e-06 28.3 0.0 2.3 2 0 0 2 2 2 2 Uncharacterised ACR, YggU family COG1872 HALZ PF02183.13 AIN97616.1 - 0.011 15.3 2.2 0.011 15.3 1.5 7.5 7 1 1 8 8 8 0 Homeobox associated leucine zipper KxDL PF10241.4 AIN97616.1 - 0.017 15.0 8.0 0.017 15.0 5.5 4.7 3 2 1 4 4 4 0 Uncharacterized conserved protein FlaC_arch PF05377.6 AIN97616.1 - 0.4 10.6 0.1 0.4 10.6 0.1 6.4 5 2 1 6 6 6 0 Flagella accessory protein C (FlaC) Baculo_PEP_C PF04513.7 AIN97616.1 - 6.5 6.5 31.4 6.1 6.6 8.5 4.4 2 2 2 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus zf-CSL PF05207.8 AIN97617.1 - 0.56 9.7 7.3 1 8.9 5.0 1.4 1 0 0 1 1 1 0 CSL zinc finger HpcH_HpaI PF03328.9 AIN97618.1 - 0.0052 15.7 0.1 0.011 14.5 0.1 1.5 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family DUF3619 PF12279.3 AIN97618.1 - 0.006 16.6 0.2 0.031 14.3 0.1 2.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3619) HA2 PF04408.18 AIN97619.1 - 1.2e-14 54.1 0.0 5.5e-14 52.0 0.0 2.2 2 0 0 2 2 2 1 Helicase associated domain (HA2) Helicase_C PF00271.26 AIN97619.1 - 1.2e-08 34.7 0.0 5e-08 32.6 0.0 2.1 1 1 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 AIN97619.1 - 2.6e-08 33.5 0.2 8.6e-08 31.8 0.1 1.9 1 1 0 1 1 1 1 DEAD/DEAH box helicase dsrm PF00035.20 AIN97619.1 - 0.0002 21.8 0.3 0.038 14.5 0.1 2.9 2 0 0 2 2 2 1 Double-stranded RNA binding motif AAA_22 PF13401.1 AIN97619.1 - 0.00075 19.6 0.1 0.003 17.7 0.0 2.0 1 0 0 1 1 1 1 AAA domain T2SE PF00437.15 AIN97619.1 - 0.0042 16.0 0.0 0.0088 14.9 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein OB_NTP_bind PF07717.11 AIN97619.1 - 0.025 14.3 0.0 0.073 12.9 0.0 1.8 1 0 0 1 1 1 0 Oligonucleotide/oligosaccharide-binding (OB)-fold KaiC PF06745.8 AIN97619.1 - 0.16 11.0 0.0 0.33 10.0 0.0 1.4 1 0 0 1 1 1 0 KaiC AAA_14 PF13173.1 AIN97619.1 - 0.36 10.7 0.2 4.4 7.2 0.1 2.6 2 1 0 2 2 2 0 AAA domain NB-ARC PF00931.17 AIN97619.1 - 0.4 9.5 0.0 0.65 8.7 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain Rad17 PF03215.10 AIN97619.1 - 0.42 9.2 0.0 0.66 8.5 0.0 1.2 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein Amastin PF07344.6 AIN97622.1 - 2.3e-47 160.4 13.9 2.8e-47 160.2 9.6 1.1 1 0 0 1 1 1 1 Amastin surface glycoprotein HlyIII PF03006.15 AIN97622.1 - 1.7 7.9 13.1 3.7 6.8 8.7 1.8 1 1 0 1 1 1 0 Haemolysin-III related Claudin_2 PF13903.1 AIN97622.1 - 2.5 7.7 18.4 0.52 9.9 10.0 1.7 1 1 1 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction Amastin PF07344.6 AIN97623.1 - 4.4e-45 153.0 4.2 5.1e-45 152.8 2.9 1.0 1 0 0 1 1 1 1 Amastin surface glycoprotein Claudin_2 PF13903.1 AIN97623.1 - 0.00087 19.0 3.1 0.00087 19.0 2.1 1.9 1 1 1 2 2 2 1 PMP-22/EMP/MP20/Claudin tight junction Shisa PF13908.1 AIN97623.1 - 0.015 15.4 0.0 0.015 15.4 0.0 1.8 2 1 0 2 2 2 0 Wnt and FGF inhibitory regulator ATP1G1_PLM_MAT8 PF02038.11 AIN97623.1 - 0.1 11.6 0.4 0.1 11.6 0.3 2.1 3 0 0 3 3 3 0 ATP1G1/PLM/MAT8 family DUF843 PF05814.6 AIN97623.1 - 6.9 6.5 6.1 8.4 6.2 0.3 2.3 2 0 0 2 2 2 0 Baculovirus protein of unknown function (DUF843) Exo_endo_phos PF03372.18 AIN97624.1 - 1.7e-14 54.3 0.1 3.6e-14 53.3 0.1 1.6 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family DUF972 PF06156.8 AIN97625.1 - 2.9 8.2 4.5 1.3 9.3 0.9 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF972) DNA_pol_A_exo1 PF01612.15 AIN97626.1 - 5.4e-14 52.0 0.0 1.5e-13 50.5 0.0 1.7 1 0 0 1 1 1 1 3'-5' exonuclease zf-CCCH PF00642.19 AIN97626.1 - 0.013 15.2 0.8 0.013 15.2 0.6 1.9 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Thioesterase PF00975.15 AIN97626.1 - 0.11 12.6 0.1 0.25 11.5 0.0 1.6 2 0 0 2 2 2 0 Thioesterase domain NIF PF03031.13 AIN97628.1 - 1.2e-30 106.3 0.1 6.1e-30 103.9 0.0 2.1 1 1 1 2 2 2 1 NLI interacting factor-like phosphatase Phage_X PF05155.10 AIN97628.1 - 0.041 13.8 0.1 0.089 12.7 0.1 1.5 1 0 0 1 1 1 0 Phage X family DUF2608 PF11019.3 AIN97628.1 - 0.053 12.5 0.0 2.4 7.0 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF2608) DUF1843 PF08898.5 AIN97628.1 - 0.16 11.9 2.0 0.59 10.2 1.4 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF1843) DNA_pol_A PF00476.15 AIN97629.1 - 7.8e-71 238.7 0.0 4.3e-64 216.5 0.0 2.5 2 1 0 2 2 2 2 DNA polymerase family A TFIIA PF03153.8 AIN97629.1 - 7.6 6.3 10.0 15 5.3 7.0 1.5 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF3595 PF12166.3 AIN97630.1 - 5.3e-121 404.3 0.0 7.1e-121 403.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3595) DUF2605 PF10792.4 AIN97632.1 - 0.11 12.1 0.1 0.28 10.9 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2605) Calpain_inhib PF00748.14 AIN97632.1 - 5.3 7.3 5.7 0.91 9.8 0.3 2.3 3 0 0 3 3 3 0 Calpain inhibitor OsmC PF02566.14 AIN97633.1 - 9.6e-07 28.9 0.3 2e-06 27.9 0.2 1.5 1 0 0 1 1 1 1 OsmC-like protein Peptidase_S49 PF01343.13 AIN97634.1 - 0.16 11.7 3.5 0.27 11.0 0.7 2.3 2 0 0 2 2 2 0 Peptidase family S49 BCS1_N PF08740.6 AIN97636.1 - 2.7e-35 121.6 2.3 4.1e-35 121.1 1.6 1.3 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.24 AIN97636.1 - 6.6e-20 71.6 0.0 1.8e-19 70.2 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 AIN97636.1 - 0.0008 19.1 0.6 0.0096 15.6 0.2 2.8 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 AIN97636.1 - 0.0008 19.4 0.2 0.0038 17.2 0.1 2.0 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 AIN97636.1 - 0.0017 18.4 0.0 0.015 15.4 0.0 2.2 2 1 0 2 2 2 1 AAA domain AAA_11 PF13086.1 AIN97636.1 - 0.0018 17.9 0.0 0.0039 16.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain DUF815 PF05673.8 AIN97636.1 - 0.0018 17.2 0.0 0.0037 16.2 0.0 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_17 PF13207.1 AIN97636.1 - 0.002 18.9 0.0 0.0042 17.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.7 AIN97636.1 - 0.0021 17.1 0.0 0.0039 16.2 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_14 PF13173.1 AIN97636.1 - 0.0029 17.5 0.0 0.0056 16.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.22 AIN97636.1 - 0.0033 17.7 0.0 0.0075 16.5 0.0 1.6 1 0 0 1 1 1 1 ABC transporter RNA_helicase PF00910.17 AIN97636.1 - 0.0068 16.5 0.0 0.018 15.1 0.0 1.8 1 0 0 1 1 1 1 RNA helicase AAA_33 PF13671.1 AIN97636.1 - 0.0072 16.2 0.0 0.016 15.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 AIN97636.1 - 0.012 15.2 0.0 0.031 14.0 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain Rad17 PF03215.10 AIN97636.1 - 0.016 13.9 0.0 0.026 13.2 0.0 1.4 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein Arch_ATPase PF01637.13 AIN97636.1 - 0.021 14.5 0.0 6.8 6.3 0.0 2.3 1 1 1 2 2 2 0 Archaeal ATPase AAA_25 PF13481.1 AIN97636.1 - 0.033 13.5 0.0 0.11 11.9 0.0 1.8 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 AIN97636.1 - 0.059 13.0 0.0 0.17 11.5 0.0 1.8 1 0 0 1 1 1 0 NACHT domain AAA_18 PF13238.1 AIN97636.1 - 0.097 12.9 0.0 0.41 10.9 0.0 2.0 2 0 0 2 2 2 0 AAA domain TIP49 PF06068.8 AIN97636.1 - 0.12 11.1 0.0 0.19 10.4 0.0 1.2 1 0 0 1 1 1 0 TIP49 C-terminus Sfi1 PF08457.5 AIN97637.1 - 0.4 9.0 71.1 0.8 8.0 0.6 3.5 2 1 0 2 2 2 0 Sfi1 spindle body protein DUF3166 PF11365.3 AIN97638.1 - 0.0027 18.1 1.9 0.086 13.3 0.2 3.0 2 1 1 3 3 3 1 Protein of unknown function (DUF3166) DUF2220 PF09983.4 AIN97640.1 - 0.0038 16.3 0.7 0.0038 16.3 0.5 1.9 2 0 0 2 2 2 1 Uncharacterized protein conserved in bacteria C-term(DUF2220) Chorein_N PF12624.2 AIN97642.1 - 8.3e-30 102.7 0.0 1.6e-29 101.8 0.0 1.5 1 0 0 1 1 1 1 N-terminal region of Chorein, a TM vesicle-mediated sorter DUF1162 PF06650.7 AIN97642.1 - 1e-18 67.5 0.0 1.1e-14 54.3 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF1162) PapD_C PF02753.12 AIN97642.1 - 0.68 9.8 0.0 4.7 7.1 0.0 2.3 2 0 0 2 2 2 0 Pili assembly chaperone PapD, C-terminal domain 2-Hacid_dh_C PF02826.14 AIN97643.1 - 5.3e-45 152.7 0.0 6.2e-45 152.5 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AdoHcyase_NAD PF00670.16 AIN97643.1 - 1.6e-06 28.0 0.3 2.8e-06 27.2 0.2 1.4 1 1 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain NAD_binding_2 PF03446.10 AIN97643.1 - 5.1e-05 23.1 0.1 7e-05 22.7 0.1 1.1 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase IlvN PF07991.7 AIN97643.1 - 5.5e-05 22.5 0.0 7.3e-05 22.1 0.0 1.2 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain NAD_binding_10 PF13460.1 AIN97643.1 - 0.00012 22.1 0.0 0.00016 21.7 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding F420_oxidored PF03807.12 AIN97643.1 - 0.0017 18.7 0.2 0.0036 17.7 0.0 1.6 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent AlaDh_PNT_C PF01262.16 AIN97643.1 - 0.034 13.7 0.0 0.59 9.6 0.0 2.2 1 1 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox PF00070.22 AIN97643.1 - 0.034 14.5 0.2 0.067 13.5 0.2 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase ELFV_dehydrog PF00208.16 AIN97643.1 - 0.045 13.3 0.0 0.074 12.6 0.0 1.3 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase TrkA_N PF02254.13 AIN97643.1 - 0.11 12.5 0.2 0.18 11.8 0.1 1.4 1 0 0 1 1 1 0 TrkA-N domain DUF1143 PF06608.6 AIN97644.1 - 0.013 15.4 0.0 0.025 14.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1143) PTEN_C2 PF10409.4 AIN97645.1 - 4.3e-10 39.4 0.0 7.2e-10 38.7 0.0 1.4 1 0 0 1 1 1 1 C2 domain of PTEN tumour-suppressor protein DSPc PF00782.15 AIN97645.1 - 4.9e-09 35.8 0.1 9.1e-09 34.9 0.1 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 AIN97645.1 - 0.00011 21.6 0.0 0.00021 20.7 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.1 AIN97645.1 - 0.004 17.4 0.5 0.011 16.0 0.3 1.6 1 0 0 1 1 1 1 Tyrosine phosphatase family PTPlike_phytase PF14566.1 AIN97645.1 - 0.019 14.9 0.1 0.034 14.2 0.1 1.3 1 0 0 1 1 1 0 Inositol hexakisphosphate CDKN3 PF05706.7 AIN97645.1 - 0.14 11.6 0.2 0.25 10.8 0.2 1.4 1 0 0 1 1 1 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) R3H-assoc PF13902.1 AIN97647.1 - 1.1e-17 64.2 0.2 1.8e-17 63.5 0.2 1.4 1 0 0 1 1 1 1 R3H-associated N-terminal domain R3H PF01424.17 AIN97647.1 - 0.0024 17.5 0.1 0.009 15.6 0.0 2.0 2 0 0 2 2 2 1 R3H domain 2Fe-2S_thioredx PF01257.14 AIN97647.1 - 0.16 11.5 0.0 0.35 10.4 0.0 1.5 1 0 0 1 1 1 0 Thioredoxin-like [2Fe-2S] ferredoxin PPR_2 PF13041.1 AIN97648.1 - 0.14 12.1 0.0 31 4.6 0.0 3.4 4 0 0 4 4 4 0 PPR repeat family EAP30 PF04157.11 AIN97649.1 - 1.6e-85 285.8 0.4 2.5e-85 285.1 0.3 1.3 1 1 0 1 1 1 1 EAP30/Vps36 family MerR-DNA-bind PF09278.6 AIN97649.1 - 6 7.3 8.7 0.99 9.8 3.2 1.8 2 0 0 2 2 2 0 MerR, DNA binding YueH PF14166.1 AIN97651.1 - 0.016 14.9 0.1 4.8 7.0 0.0 2.6 2 0 0 2 2 2 0 YueH-like protein DUF3808 PF10300.4 AIN97652.1 - 6.1e-40 137.1 1.1 6.1e-40 137.1 0.8 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF3808) Cut8_C PF08559.5 AIN97652.1 - 0.038 13.8 0.9 1.8 8.3 0.0 2.5 2 0 0 2 2 2 0 Cut8 six-helix bundle p25-alpha PF05517.7 AIN97654.1 - 1.8e-39 135.4 3.2 2e-39 135.3 2.2 1.0 1 0 0 1 1 1 1 p25-alpha Amastin PF07344.6 AIN97655.1 - 1.5e-46 157.8 14.6 1.8e-46 157.6 10.1 1.1 1 0 0 1 1 1 1 Amastin surface glycoprotein PIG-P PF08510.7 AIN97655.1 - 9.1 5.9 11.1 2.2 7.9 0.0 3.1 2 1 1 3 3 3 0 PIG-P Amastin PF07344.6 AIN97656.1 - 2.5e-50 170.1 8.0 3e-50 169.8 5.5 1.1 1 0 0 1 1 1 1 Amastin surface glycoprotein Rab5ip PF07019.7 AIN97656.1 - 0.47 10.6 6.2 2.1 8.5 1.7 2.7 2 1 0 2 2 2 0 Rab5-interacting protein (Rab5ip) Claudin_2 PF13903.1 AIN97656.1 - 0.95 9.1 15.4 0.018 14.7 5.6 1.7 2 0 0 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction FA_desaturase PF00487.19 AIN97656.1 - 1.4 8.2 4.3 2.7 7.3 2.9 1.6 1 1 0 1 1 1 0 Fatty acid desaturase DUF3925 PF13063.1 AIN97656.1 - 1.7 8.7 8.3 2.3 8.2 0.4 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3925) GspL_C PF12693.2 AIN97657.1 - 0.39 10.4 5.0 1.8 8.2 0.5 2.4 2 0 0 2 2 2 0 GspL periplasmic domain Amastin PF07344.6 AIN97658.1 - 3.3e-48 163.2 17.1 4e-48 162.9 11.8 1.1 1 0 0 1 1 1 1 Amastin surface glycoprotein DUF3767 PF12597.3 AIN97658.1 - 0.18 11.4 0.5 0.58 9.8 0.0 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3767) SUR7 PF06687.7 AIN97658.1 - 5.7 6.4 24.2 1.8 8.0 0.4 3.0 2 1 1 3 3 3 0 SUR7/PalI family Amastin PF07344.6 AIN97659.1 - 5.7e-52 175.4 11.1 6.7e-52 175.2 7.7 1.0 1 0 0 1 1 1 1 Amastin surface glycoprotein DUF1467 PF07330.7 AIN97659.1 - 0.1 12.3 6.0 3.9 7.3 0.0 3.6 4 0 0 4 4 4 0 Protein of unknown function (DUF1467) Vpu PF00558.14 AIN97659.1 - 2.3 7.8 4.7 2.8 7.5 0.4 2.8 2 1 1 3 3 3 0 Vpu protein Zeta_toxin PF06414.7 AIN97660.1 - 1.7e-11 43.6 0.0 6.5e-11 41.7 0.0 1.9 2 0 0 2 2 2 1 Zeta toxin AAA_33 PF13671.1 AIN97660.1 - 0.00089 19.1 0.0 0.0024 17.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 AIN97660.1 - 0.1 12.9 0.4 0.39 11.0 0.0 2.1 2 0 0 2 2 2 0 AAA domain Peptidase_C15 PF01470.12 AIN97661.1 - 1.5e-11 44.5 0.4 0.00011 22.1 0.1 2.2 2 0 0 2 2 2 2 Pyroglutamyl peptidase RCC1 PF00415.13 AIN97663.1 - 1e-21 76.8 1.6 5.9e-08 32.7 0.0 4.5 4 0 0 4 4 4 4 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 AIN97663.1 - 1.9e-16 59.1 8.9 1.2e-09 37.5 1.3 5.5 5 0 0 5 5 5 4 Regulator of chromosome condensation (RCC1) repeat TPR_12 PF13424.1 AIN97664.1 - 1.7e-06 27.8 2.5 2.8e-05 23.9 0.2 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat IQ PF00612.22 AIN97664.1 - 0.0027 17.1 0.3 0.0027 17.1 0.2 8.1 9 0 0 9 9 9 5 IQ calmodulin-binding motif TPR_11 PF13414.1 AIN97664.1 - 0.0048 16.5 0.0 0.023 14.3 0.0 2.2 2 0 0 2 2 2 1 TPR repeat DEAD PF00270.24 AIN97666.1 - 4.4e-42 143.4 0.1 3.2e-41 140.6 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 AIN97666.1 - 5.7e-21 74.1 0.0 1.4e-20 72.9 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DBP10CT PF08147.7 AIN97666.1 - 5.2e-09 35.7 3.0 1.2e-08 34.6 2.1 1.6 1 0 0 1 1 1 1 DBP10CT (NUC160) domain ResIII PF04851.10 AIN97666.1 - 0.0099 15.7 0.0 0.049 13.4 0.0 2.2 2 1 1 3 3 3 1 Type III restriction enzyme, res subunit FtsX PF02687.16 AIN97668.1 - 1.3e-25 89.5 34.9 3.5e-15 55.8 8.8 5.4 5 1 2 7 7 7 2 FtsX-like permease family Pkinase PF00069.20 AIN97670.1 - 4.3e-54 183.4 0.0 5.2e-54 183.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AIN97670.1 - 6.8e-31 107.2 0.0 1.2e-30 106.4 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 AIN97670.1 - 0.0022 17.0 0.0 0.003 16.5 0.0 1.2 1 0 0 1 1 1 1 Kinase-like PLDc_2 PF13091.1 AIN97672.1 - 3.8e-25 88.0 0.0 1.4e-18 66.8 0.0 2.3 2 0 0 2 2 2 2 PLD-like domain PLDc PF00614.17 AIN97672.1 - 2.5e-05 23.9 1.9 0.0067 16.2 0.6 2.6 2 0 0 2 2 2 2 Phospholipase D Active site motif Tim17 PF02466.14 AIN97673.1 - 0.17 11.9 4.6 0.33 10.9 3.2 1.5 1 1 0 1 1 1 0 Tim17/Tim22/Tim23/Pmp24 family ubiquitin PF00240.18 AIN97674.1 - 1.3e-16 59.7 0.0 1.5e-16 59.5 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 AIN97674.1 - 1.2e-07 31.2 0.0 1.3e-07 31.1 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Rad60-SLD_2 PF13881.1 AIN97674.1 - 0.00099 18.9 0.1 0.002 17.9 0.1 1.6 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 AIN97674.1 - 0.026 14.7 0.0 0.06 13.6 0.0 1.7 1 1 0 1 1 1 0 Ubiquitin-like domain DoxX PF07681.7 AIN97675.1 - 0.0062 16.9 5.7 0.0062 16.9 4.0 1.7 2 1 0 2 2 2 1 DoxX TMEM101 PF15111.1 AIN97675.1 - 0.0063 15.8 0.4 0.0079 15.5 0.3 1.2 1 0 0 1 1 1 1 TMEM101 protein family HR_lesion PF05514.6 AIN97675.1 - 0.25 11.1 2.5 0.31 10.8 1.7 1.3 1 1 0 1 1 1 0 HR-like lesion-inducing DUF4229 PF14012.1 AIN97675.1 - 6.3 6.7 9.3 6.4 6.7 0.3 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF4229) SIR2 PF02146.12 AIN97676.1 - 5.1e-45 153.3 0.0 6.5e-45 153.0 0.0 1.1 1 0 0 1 1 1 1 Sir2 family Glyco_transf_28 PF03033.15 AIN97676.1 - 0.06 13.1 0.1 0.19 11.4 0.0 1.9 2 0 0 2 2 2 0 Glycosyltransferase family 28 N-terminal domain Sulfotransfer_1 PF00685.22 AIN97676.1 - 0.13 11.5 0.1 0.23 10.6 0.0 1.5 2 0 0 2 2 2 0 Sulfotransferase domain Pkinase PF00069.20 AIN97677.1 - 1.6e-45 155.2 0.0 2.3e-44 151.4 0.0 2.2 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AIN97677.1 - 7.9e-26 90.6 0.0 1.3e-22 80.1 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 AIN97677.1 - 0.0082 15.1 0.0 0.016 14.1 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 AIN97677.1 - 0.028 13.4 0.0 0.06 12.3 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family OGG_N PF07934.7 AIN97679.1 - 1.2e-28 99.4 0.3 2.1e-28 98.6 0.2 1.4 1 0 0 1 1 1 1 8-oxoguanine DNA glycosylase, N-terminal domain HhH-GPD PF00730.20 AIN97679.1 - 3.3e-10 40.2 0.0 2.1e-09 37.5 0.0 2.1 1 1 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.18 AIN97679.1 - 0.00066 19.2 0.0 0.0027 17.3 0.0 2.0 2 0 0 2 2 2 1 Helix-hairpin-helix motif HEAT_2 PF13646.1 AIN97680.1 - 0.00029 21.0 1.6 0.0077 16.4 0.0 3.2 2 0 0 2 2 2 1 HEAT repeats Pkinase PF00069.20 AIN97681.1 - 4.1e-51 173.6 0.0 1.1e-26 93.6 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 AIN97681.1 - 2.3e-28 98.9 0.0 2.5e-16 59.5 0.0 2.5 2 1 0 2 2 2 2 Protein tyrosine kinase DSPc PF00782.15 AIN97681.1 - 7.9e-27 93.4 0.0 1.6e-26 92.4 0.0 1.5 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain LRR_4 PF12799.2 AIN97681.1 - 7.4e-10 38.2 8.7 3.7e-06 26.4 1.6 3.8 2 1 1 3 3 3 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 AIN97681.1 - 7.8e-09 35.1 6.6 2.5e-07 30.3 2.7 3.3 2 1 0 2 2 2 1 Leucine rich repeat LRR_1 PF00560.28 AIN97681.1 - 1.1e-08 33.9 7.4 0.13 12.4 0.1 6.3 5 0 0 5 5 5 3 Leucine Rich Repeat LRR_7 PF13504.1 AIN97681.1 - 9.4e-07 28.0 3.8 0.58 10.5 0.0 5.4 4 0 0 4 4 4 2 Leucine rich repeat Y_phosphatase PF00102.22 AIN97681.1 - 0.00054 19.3 0.0 0.00099 18.5 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase ZZ PF00569.12 AIN97681.1 - 0.19 11.3 3.7 0.52 9.8 2.6 1.8 1 0 0 1 1 1 0 Zinc finger, ZZ type Thioredoxin PF00085.15 AIN97682.1 - 1.5e-25 88.8 0.0 1.4e-24 85.7 0.0 2.3 2 0 0 2 2 2 1 Thioredoxin Thioredoxin_2 PF13098.1 AIN97682.1 - 4.2e-09 36.5 0.1 8.4e-08 32.4 0.0 3.0 3 1 0 3 3 3 1 Thioredoxin-like domain Thioredoxin_8 PF13905.1 AIN97682.1 - 1.7e-07 31.2 0.1 5.5e-05 23.1 0.0 3.5 4 1 1 5 5 4 1 Thioredoxin-like Thioredoxin_7 PF13899.1 AIN97682.1 - 1.6e-05 24.7 0.0 4.3e-05 23.4 0.0 1.7 1 0 0 1 1 1 1 Thioredoxin-like Redoxin PF08534.5 AIN97682.1 - 5.7e-05 22.7 0.0 0.0002 20.9 0.0 1.9 2 0 0 2 2 2 1 Redoxin Thioredoxin_6 PF13848.1 AIN97682.1 - 0.00042 20.1 0.0 0.0064 16.3 0.0 2.5 2 1 1 3 3 3 2 Thioredoxin-like domain Thioredoxin_9 PF14595.1 AIN97682.1 - 0.00084 18.9 0.0 0.0022 17.5 0.0 1.7 1 0 0 1 1 1 1 Thioredoxin AhpC-TSA PF00578.16 AIN97682.1 - 0.0021 17.7 0.0 0.0092 15.6 0.0 2.1 2 0 0 2 2 2 1 AhpC/TSA family DUF2644 PF10841.3 AIN97682.1 - 0.092 12.7 0.1 0.2 11.7 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2644) Thioredoxin_4 PF13462.1 AIN97682.1 - 0.099 12.6 0.0 0.19 11.7 0.0 1.6 1 0 0 1 1 1 0 Thioredoxin SUKH-3 PF14433.1 AIN97682.1 - 0.11 12.2 0.0 0.21 11.3 0.0 1.5 1 0 0 1 1 1 0 SUKH-3 immunity protein Mito_fiss_reg PF05308.6 AIN97683.1 - 2 7.7 13.5 1.2 8.4 1.8 2.9 2 0 0 2 2 2 0 Mitochondrial fission regulator Exo_endo_phos PF03372.18 AIN97684.1 - 2.5e-13 50.5 0.0 6.3e-13 49.2 0.0 1.7 2 0 0 2 2 2 1 Endonuclease/Exonuclease/phosphatase family DUF2755 PF10954.3 AIN97685.1 - 0.073 12.7 2.1 0.082 12.6 0.4 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF2755) DUF1751 PF08551.5 AIN97685.1 - 0.14 12.4 2.0 1.6 9.1 0.1 2.3 2 0 0 2 2 2 0 Eukaryotic integral membrane protein (DUF1751) Pox_P21 PF05313.7 AIN97685.1 - 2.9 7.1 6.0 3.6 6.7 4.1 1.2 1 0 0 1 1 1 0 Poxvirus P21 membrane protein Glyco_hydro_65m PF03632.10 AIN97686.1 - 7.8e-37 126.8 0.0 1.1e-36 126.3 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 65 central catalytic domain Glyco_hydro_65C PF03633.10 AIN97686.1 - 1.4e-05 25.1 0.0 3.5e-05 23.8 0.0 1.7 1 0 0 1 1 1 1 Glycosyl hydrolase family 65, C-terminal domain HAD_2 PF13419.1 AIN97686.1 - 0.0002 21.6 0.0 0.00053 20.2 0.0 1.7 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Glyco_hydro_65N PF03636.10 AIN97686.1 - 0.12 11.6 0.0 0.2 10.9 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolase family 65, N-terminal domain Kelch_5 PF13854.1 AIN97687.1 - 5.7e-14 51.6 8.2 2.2e-05 24.2 0.2 6.6 7 0 0 7 7 7 3 Kelch motif Kelch_3 PF13415.1 AIN97687.1 - 2.4e-12 46.6 17.9 3.7e-07 30.1 0.1 8.7 10 0 0 10 10 10 2 Galactose oxidase, central domain Kelch_1 PF01344.20 AIN97687.1 - 5.4e-12 45.0 3.9 2.2e-05 23.9 0.1 4.5 4 1 1 5 5 5 3 Kelch motif Kelch_4 PF13418.1 AIN97687.1 - 1.5e-10 40.6 19.6 2.1e-07 30.6 0.0 6.1 7 0 0 7 7 7 3 Galactose oxidase, central domain Kelch_6 PF13964.1 AIN97687.1 - 1.7e-07 31.1 4.4 0.012 15.7 0.0 5.6 5 1 1 6 6 6 2 Kelch motif Kelch_2 PF07646.10 AIN97687.1 - 5.2e-06 25.9 7.5 0.43 10.4 0.0 5.6 5 0 0 5 5 5 2 Kelch motif DUF1664 PF07889.7 AIN97687.1 - 0.28 11.0 0.4 0.91 9.3 0.2 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) HA2 PF04408.18 AIN97688.1 - 1.5e-16 60.2 0.0 2.7e-16 59.4 0.0 1.4 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.26 AIN97688.1 - 5e-12 45.5 0.0 1.2e-11 44.3 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain OB_NTP_bind PF07717.11 AIN97688.1 - 1.6e-10 40.8 0.0 5.3e-10 39.1 0.0 1.9 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold DEAD PF00270.24 AIN97688.1 - 7.9e-08 31.9 0.8 3.9e-07 29.7 0.3 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_22 PF13401.1 AIN97688.1 - 2.4e-05 24.4 0.0 5.9e-05 23.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain T2SE PF00437.15 AIN97688.1 - 0.0006 18.7 0.0 0.0012 17.8 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_19 PF13245.1 AIN97688.1 - 0.0025 17.5 2.1 0.0053 16.4 0.2 2.5 2 0 0 2 2 2 1 Part of AAA domain ResIII PF04851.10 AIN97688.1 - 0.0027 17.5 0.0 2.1 8.1 0.0 2.3 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit SRP54 PF00448.17 AIN97688.1 - 0.0035 16.8 0.2 0.011 15.1 0.1 1.8 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain AAA_25 PF13481.1 AIN97688.1 - 0.0035 16.7 0.0 0.009 15.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.1 AIN97688.1 - 0.0082 15.6 0.0 0.022 14.2 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain NACHT PF05729.7 AIN97688.1 - 0.0082 15.8 0.0 0.041 13.5 0.0 2.2 2 0 0 2 2 2 1 NACHT domain AAA_16 PF13191.1 AIN97688.1 - 0.01 15.8 1.6 0.043 13.8 0.3 2.6 2 1 0 2 2 2 0 AAA ATPase domain Flavi_DEAD PF07652.9 AIN97688.1 - 0.016 14.9 0.2 0.033 13.9 0.1 1.5 1 0 0 1 1 1 0 Flavivirus DEAD domain cobW PF02492.14 AIN97688.1 - 0.017 14.6 0.3 0.35 10.2 0.0 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_30 PF13604.1 AIN97688.1 - 0.022 14.3 0.0 0.045 13.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.1 AIN97688.1 - 0.08 13.2 0.0 0.13 12.5 0.0 1.2 1 0 0 1 1 1 0 AAA domain Dynamin_N PF00350.18 AIN97689.1 - 2.5e-19 69.7 0.0 2.6e-18 66.4 0.0 2.3 1 1 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.18 AIN97689.1 - 4.2e-09 36.3 0.0 1e-08 35.1 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 AIN97689.1 - 0.011 16.2 0.5 7.3 7.1 0.0 3.7 4 0 0 4 4 4 0 Miro-like protein Cofilin_ADF PF00241.15 AIN97691.1 - 1.9e-13 50.3 0.2 5e-09 36.1 0.0 2.3 2 0 0 2 2 2 2 Cofilin/tropomyosin-type actin-binding protein DUF587 PF04532.7 AIN97691.1 - 0.083 11.8 0.0 0.13 11.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF587) MMgT PF10270.4 AIN97694.1 - 0.00081 19.7 2.1 0.0069 16.8 1.4 2.4 1 1 0 1 1 1 1 Membrane magnesium transporter Clat_adaptor_s PF01217.15 AIN97695.1 - 7.1e-51 171.6 4.2 7.9e-51 171.5 2.9 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain tRNA-synt_2 PF00152.15 AIN97696.1 - 3.4e-71 239.7 0.0 4.4e-71 239.3 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_synt_1c_R1 PF04558.10 AIN97696.1 - 1.4e-42 145.0 0.6 2.2e-42 144.3 0.4 1.3 1 0 0 1 1 1 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 tRNA_anti-codon PF01336.20 AIN97696.1 - 1.1e-09 38.0 0.0 2.4e-09 36.9 0.0 1.6 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain DUF2046 PF09755.4 AIN97698.1 - 0.00012 21.1 21.6 0.00012 21.1 15.0 2.9 2 1 0 2 2 2 1 Uncharacterized conserved protein H4 (DUF2046) THOC7 PF05615.8 AIN97698.1 - 0.33 11.2 20.7 1.8 8.8 0.3 2.9 2 1 0 2 2 2 0 Tho complex subunit 7 Endotoxin_N PF03945.9 AIN97698.1 - 0.39 10.0 3.0 0.35 10.2 0.8 1.8 2 0 0 2 2 2 0 delta endotoxin, N-terminal domain DUF3166 PF11365.3 AIN97698.1 - 1.2 9.6 15.4 2.4 8.6 0.0 4.0 2 1 1 3 3 3 0 Protein of unknown function (DUF3166) IncA PF04156.9 AIN97698.1 - 1.2 8.6 21.1 1 8.9 0.3 2.5 2 0 0 2 2 2 0 IncA protein TMPIT PF07851.8 AIN97698.1 - 2.7 6.9 14.7 3 6.8 3.8 2.2 2 0 0 2 2 2 0 TMPIT-like protein DUF3866 PF12982.2 AIN97698.1 - 4.4 6.1 8.6 0.59 9.0 0.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3866) V_ATPase_I PF01496.14 AIN97698.1 - 8.4 4.1 12.1 1.8 6.2 5.5 1.8 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family DUF745 PF05335.8 AIN97698.1 - 9.4 5.7 26.3 0.77 9.2 8.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF745) CBFD_NFYB_HMF PF00808.18 AIN97699.1 - 1.2e-05 25.2 0.5 2.2e-05 24.4 0.3 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 AIN97699.1 - 0.0021 18.1 0.3 0.0037 17.3 0.2 1.5 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 EF-hand_7 PF13499.1 AIN97701.1 - 2.4e-22 78.8 3.7 4.4e-14 52.3 0.4 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.27 AIN97701.1 - 3.5e-22 75.9 6.5 1.3e-07 30.3 0.9 3.5 3 0 0 3 3 3 3 EF hand EF-hand_6 PF13405.1 AIN97701.1 - 5.1e-20 69.5 4.0 2.5e-06 26.8 0.0 3.5 3 0 0 3 3 3 3 EF-hand domain EF-hand_8 PF13833.1 AIN97701.1 - 1.7e-15 56.3 10.3 1.3e-12 47.1 0.9 3.7 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_5 PF13202.1 AIN97701.1 - 2.1e-14 52.1 4.2 0.00048 19.3 0.5 3.5 3 0 0 3 3 3 3 EF hand EF-hand_9 PF14658.1 AIN97701.1 - 4e-12 45.8 0.2 3.7e-06 26.7 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.2 AIN97701.1 - 1.1e-06 28.2 0.8 0.004 16.8 0.1 2.2 2 0 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand DUF3164 PF11363.3 AIN97701.1 - 0.0034 16.8 1.0 0.14 11.5 0.0 2.4 1 1 2 3 3 3 1 Protein of unknown function (DUF3164) Caleosin PF05042.8 AIN97701.1 - 0.026 14.0 0.1 0.26 10.8 0.0 2.2 2 1 1 3 3 3 0 Caleosin related protein MgtE_N PF03448.12 AIN97701.1 - 0.028 14.7 0.7 0.028 14.7 0.5 2.5 3 0 0 3 3 3 0 MgtE intracellular N domain TerB PF05099.8 AIN97701.1 - 0.054 13.2 6.0 0.25 11.0 0.8 2.6 1 1 3 4 4 4 0 Tellurite resistance protein TerB SPARC_Ca_bdg PF10591.4 AIN97701.1 - 0.098 12.6 2.3 1.4 9.0 0.4 2.2 1 1 1 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region LTXXQ PF07813.7 AIN97701.1 - 0.32 11.4 6.3 0.3 11.5 0.9 2.2 1 1 0 2 2 2 0 LTXXQ motif family protein Aminotran_4 PF01063.14 AIN97703.1 - 1.7e-25 89.8 0.0 2.2e-25 89.4 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class IV Glycos_transf_1 PF00534.15 AIN97704.1 - 9.5e-27 93.4 0.0 2.1e-26 92.3 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 AIN97704.1 - 4.1e-05 23.7 0.0 8.2e-05 22.7 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.1 AIN97704.1 - 0.00042 20.5 0.0 0.0012 19.0 0.0 1.8 2 0 0 2 2 2 1 Glycosyl transferases group 1 TPR_11 PF13414.1 AIN97705.1 - 4.1e-26 90.4 18.8 2.4e-10 39.8 0.9 4.9 3 2 2 5 5 5 4 TPR repeat DnaJ PF00226.26 AIN97705.1 - 9.5e-20 70.1 0.2 2.5e-19 68.7 0.1 1.8 1 0 0 1 1 1 1 DnaJ domain TPR_1 PF00515.23 AIN97705.1 - 2.6e-14 52.0 15.9 0.00093 18.7 0.0 6.1 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_2 PF07719.12 AIN97705.1 - 2.8e-11 42.4 23.5 0.0019 17.9 0.2 7.4 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_16 PF13432.1 AIN97705.1 - 5e-05 23.8 11.8 0.47 11.2 0.1 6.3 7 0 0 7 7 6 2 Tetratricopeptide repeat TPR_12 PF13424.1 AIN97705.1 - 5.1e-05 23.1 12.5 0.00049 19.9 0.4 4.8 4 1 0 5 5 5 1 Tetratricopeptide repeat TPR_17 PF13431.1 AIN97705.1 - 0.00069 19.6 0.1 28 5.2 0.0 5.3 6 0 0 6 6 6 0 Tetratricopeptide repeat Apc3 PF12895.2 AIN97705.1 - 0.00096 19.2 12.5 0.034 14.2 0.2 4.2 3 1 1 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.1 AIN97705.1 - 0.028 14.1 12.8 0.041 13.6 0.0 5.4 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_6 PF13174.1 AIN97705.1 - 0.19 12.2 7.3 22 5.7 0.0 5.4 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_14 PF13428.1 AIN97705.1 - 0.27 11.9 14.2 19 6.2 0.6 6.5 4 2 4 8 8 8 0 Tetratricopeptide repeat TPR_7 PF13176.1 AIN97705.1 - 0.38 10.6 9.7 11 6.1 0.1 5.8 5 1 1 6 6 6 0 Tetratricopeptide repeat Dsh_C PF12316.3 AIN97706.1 - 0.072 13.2 1.2 0.11 12.6 0.9 1.4 1 1 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal Sec7 PF01369.15 AIN97707.1 - 2.8e-52 177.1 0.0 4.8e-52 176.3 0.0 1.4 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.2 AIN97707.1 - 6.8e-05 22.3 0.2 0.004 16.6 0.1 2.6 2 0 0 2 2 2 2 Guanine nucleotide exchange factor in Golgi transport N-terminal GTP_EFTU PF00009.22 AIN97708.1 - 2.4e-08 33.6 0.0 4.8e-08 32.6 0.0 1.5 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain ATP_bind_1 PF03029.12 AIN97708.1 - 0.014 14.9 2.9 0.36 10.3 0.4 2.2 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein GTP_EFTU_D3 PF03143.12 AIN97708.1 - 0.028 14.5 0.0 0.052 13.7 0.0 1.4 1 0 0 1 1 1 0 Elongation factor Tu C-terminal domain AAA_29 PF13555.1 AIN97708.1 - 0.035 13.6 0.5 0.2 11.2 0.2 2.1 2 0 0 2 2 2 0 P-loop containing region of AAA domain GTP_EFTU_D2 PF03144.20 AIN97708.1 - 0.047 13.8 0.1 0.18 11.9 0.1 2.0 1 0 0 1 1 1 0 Elongation factor Tu domain 2 Mito_morph_reg PF14972.1 AIN97708.1 - 0.088 12.2 0.0 0.18 11.1 0.0 1.5 1 0 0 1 1 1 0 Mitochondrial morphogenesis regulator ABC_tran PF00005.22 AIN97708.1 - 0.12 12.7 0.1 0.36 11.1 0.0 1.8 2 0 0 2 2 2 0 ABC transporter AAA_10 PF12846.2 AIN97708.1 - 0.18 11.2 0.1 0.28 10.5 0.0 1.2 1 0 0 1 1 1 0 AAA-like domain Ribosomal_L35Ae PF01247.13 AIN97709.1 - 2.9e-34 116.6 1.4 4.4e-34 116.1 1.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L35Ae RimM PF01782.13 AIN97709.1 - 5.1e-05 23.1 0.2 0.071 13.0 0.0 2.4 2 1 0 2 2 2 2 RimM N-terminal domain HlyIII PF03006.15 AIN97710.1 - 0.014 14.7 0.4 0.017 14.5 0.3 1.0 1 0 0 1 1 1 0 Haemolysin-III related SCAMP PF04144.8 AIN97710.1 - 0.023 14.5 0.4 0.031 14.1 0.3 1.1 1 0 0 1 1 1 0 SCAMP family TarH PF02203.10 AIN97711.1 - 0.03 14.1 0.1 0.05 13.4 0.1 1.4 1 0 0 1 1 1 0 Tar ligand binding domain homologue SPC25 PF06703.6 AIN97711.1 - 0.17 11.4 0.2 0.31 10.6 0.1 1.4 1 0 0 1 1 1 0 Microsomal signal peptidase 25 kDa subunit (SPC25) Polysacc_deac_2 PF04748.8 AIN97712.1 - 0.12 11.4 0.0 0.23 10.4 0.0 1.4 1 0 0 1 1 1 0 Divergent polysaccharide deacetylase Reo_sigmaC PF04582.7 AIN97713.1 - 0.0065 15.6 1.9 0.0065 15.6 1.3 5.5 2 1 6 8 8 8 4 Reovirus sigma C capsid protein LRR_6 PF13516.1 AIN97714.1 - 1.2e-07 31.0 0.4 0.19 11.8 0.0 4.7 5 0 0 5 5 5 3 Leucine Rich repeat LRR_1 PF00560.28 AIN97714.1 - 0.028 14.4 4.0 7.9 6.9 0.0 3.7 4 0 0 4 4 4 0 Leucine Rich Repeat WD40 PF00400.27 AIN97715.1 - 0.16 11.9 9.0 1.4 8.9 0.1 4.5 5 0 0 5 5 5 0 WD domain, G-beta repeat PP2C PF00481.16 AIN97716.1 - 1.9e-55 188.0 0.0 2.6e-55 187.5 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.1 AIN97716.1 - 0.00014 21.3 0.1 0.00036 20.0 0.0 1.7 1 1 0 1 1 1 1 Protein phosphatase 2C PP2C PF00481.16 AIN97717.1 - 8.7e-56 189.1 0.0 1.1e-55 188.7 0.0 1.1 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.1 AIN97717.1 - 0.14 11.5 0.0 0.28 10.5 0.0 1.6 1 1 0 1 1 1 0 Protein phosphatase 2C Sec7 PF01369.15 AIN97718.1 - 5.1e-52 176.3 0.0 4.5e-51 173.2 0.0 2.2 2 0 0 2 2 2 1 Sec7 domain DUF1981 PF09324.5 AIN97718.1 - 5.8e-22 77.0 0.1 2.5e-21 74.9 0.1 2.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1981) Sec7_N PF12783.2 AIN97718.1 - 8.7e-18 64.3 1.9 1.3e-17 63.7 0.3 2.2 2 0 0 2 2 2 1 Guanine nucleotide exchange factor in Golgi transport N-terminal AAA_32 PF13654.1 AIN97718.1 - 0.21 10.2 0.3 0.33 9.5 0.2 1.2 1 0 0 1 1 1 0 AAA domain CENP-F_leu_zip PF10473.4 AIN97719.1 - 0.00028 20.7 5.2 0.00028 20.7 3.6 7.3 4 1 4 8 8 8 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 FliJ PF02050.11 AIN97719.1 - 0.00056 19.9 4.7 0.00056 19.9 3.2 7.6 3 1 3 7 7 7 1 Flagellar FliJ protein APG6 PF04111.7 AIN97719.1 - 2.6 7.0 99.8 0.43 9.5 3.4 7.1 4 1 3 7 7 7 0 Autophagy protein Apg6 DUF948 PF06103.6 AIN97719.1 - 9.2 6.2 22.5 8.6 6.2 0.7 7.4 8 2 1 9 9 9 0 Bacterial protein of unknown function (DUF948) DUF972 PF06156.8 AIN97720.1 - 0.15 12.4 34.9 0.23 11.8 0.7 4.7 4 1 0 4 4 4 0 Protein of unknown function (DUF972) SpoIISA_toxin PF14171.1 AIN97720.1 - 0.19 10.9 0.1 0.19 10.9 0.0 2.3 1 1 1 2 2 2 0 Toxin SpoIISA, type II toxin-antitoxin system Filament PF00038.16 AIN97720.1 - 0.98 8.8 51.5 0.59 9.5 6.0 4.2 2 2 0 3 3 3 0 Intermediate filament protein HOOK PF05622.7 AIN97721.1 - 0.0003 18.7 8.3 0.0003 18.7 5.7 4.8 2 1 2 4 4 4 2 HOOK protein C2 PF00168.25 AIN97721.1 - 0.0031 17.3 0.0 0.0075 16.0 0.0 1.6 1 0 0 1 1 1 1 C2 domain Lebercilin PF15619.1 AIN97721.1 - 0.0035 16.7 16.6 0.0035 16.7 11.5 6.9 5 1 1 6 6 6 1 Ciliary protein causing Leber congenital amaurosis disease DUF972 PF06156.8 AIN97721.1 - 0.013 15.8 5.5 0.013 15.8 3.8 7.5 5 3 1 6 6 6 0 Protein of unknown function (DUF972) Shugoshin_N PF07558.6 AIN97721.1 - 0.06 13.0 28.2 0.31 10.7 0.1 8.4 8 1 2 10 10 10 0 Shugoshin N-terminal coiled-coil region Surfac_D-trimer PF09006.6 AIN97721.1 - 1.2 8.8 7.8 4 7.2 0.3 4.3 4 0 0 4 4 4 0 Lung surfactant protein D coiled-coil trimerisation DASH_Hsk3 PF08227.6 AIN97721.1 - 6.4 7.0 7.0 1.8 8.8 0.4 3.4 4 0 0 4 4 4 0 DASH complex subunit Hsk3 like YkyA PF10368.4 AIN97722.1 - 0.011 15.0 2.1 0.011 15.0 1.4 1.8 3 0 0 3 3 3 0 Putative cell-wall binding lipoprotein LemA PF04011.7 AIN97722.1 - 0.012 14.7 0.3 0.025 13.6 0.2 1.4 1 0 0 1 1 1 0 LemA family Exonuc_VII_L PF02601.10 AIN97722.1 - 0.57 9.3 5.6 2.1 7.4 0.4 2.5 2 1 0 2 2 2 0 Exonuclease VII, large subunit IncA PF04156.9 AIN97722.1 - 4.8 6.7 14.9 0.049 13.2 0.8 3.2 3 0 0 3 3 3 0 IncA protein IFT57 PF10498.4 AIN97722.1 - 7.5 5.1 10.4 0.044 12.5 0.8 1.9 3 0 0 3 3 3 0 Intra-flagellar transport protein 57 DUF4481 PF14800.1 AIN97723.1 - 0.022 13.6 5.0 0.036 12.9 3.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4481) Cauli_AT PF03233.8 AIN97723.1 - 0.038 13.6 0.7 0.084 12.5 0.5 1.5 1 0 0 1 1 1 0 Aphid transmission protein IncA PF04156.9 AIN97723.1 - 0.044 13.3 13.4 0.077 12.5 9.3 1.4 1 0 0 1 1 1 0 IncA protein CENP-F_leu_zip PF10473.4 AIN97723.1 - 0.3 10.9 16.3 0.53 10.1 11.3 1.4 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 TPR_MLP1_2 PF07926.7 AIN97723.1 - 4.1 7.1 17.0 6.7 6.4 11.8 1.3 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein CR6_interact PF10147.4 AIN97723.1 - 5.9 6.1 9.6 0.37 10.0 0.8 2.1 1 1 1 2 2 2 0 Growth arrest and DNA-damage-inducible proteins-interacting protein 1 DUF342 PF03961.8 AIN97723.1 - 6.2 5.1 7.0 23 3.2 4.9 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF342) FUSC PF04632.7 AIN97723.1 - 9.2 4.5 7.2 13 4.0 5.0 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family Corona_S2 PF01601.11 AIN97725.1 - 0.0017 16.5 1.5 0.0017 16.5 1.1 1.8 1 1 1 2 2 2 1 Coronavirus S2 glycoprotein MtrG PF04210.8 AIN97725.1 - 1.7 8.3 4.8 60 3.4 0.0 3.5 2 1 1 3 3 3 0 Tetrahydromethanopterin S-methyltransferase, subunit G Glyco_hydro_67N PF03648.9 AIN97725.1 - 2.2 8.3 6.7 13 5.8 0.9 3.1 2 0 0 2 2 2 0 Glycosyl hydrolase family 67 N-terminus Alba PF01918.16 AIN97726.1 - 2.1e-14 52.8 0.2 3.3e-14 52.2 0.2 1.3 1 0 0 1 1 1 1 Alba Rpp20 PF12328.3 AIN97726.1 - 0.0029 17.2 0.9 0.0047 16.5 0.6 1.4 1 1 0 1 1 1 1 Rpp20 subunit of nuclear RNase MRP and P GRP PF07172.6 AIN97726.1 - 0.48 10.9 13.6 0.063 13.7 5.5 2.1 2 0 0 2 2 2 0 Glycine rich protein family Caprin-1_C PF12287.3 AIN97726.1 - 1.4 8.2 6.3 1.9 7.8 4.3 1.2 1 0 0 1 1 1 0 Cytoplasmic activation/proliferation-associated protein-1 C term DUF3628 PF12300.3 AIN97726.1 - 2.4 8.1 17.0 0.3 11.1 7.9 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3628) Adap_comp_sub PF00928.16 AIN97727.1 - 6e-53 179.6 0.0 7.3e-53 179.3 0.0 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 AIN97727.1 - 0.00021 21.0 0.2 0.00038 20.1 0.1 1.3 1 0 0 1 1 1 1 Clathrin adaptor complex small chain ACBP PF00887.14 AIN97728.1 - 5.5e-19 67.6 1.6 5.9e-19 67.5 1.1 1.0 1 0 0 1 1 1 1 Acyl CoA binding protein SOR PF07682.6 AIN97728.1 - 0.03 12.9 0.1 0.032 12.8 0.1 1.2 1 0 0 1 1 1 0 Sulphur oxygenase reductase TIP49 PF06068.8 AIN97729.1 - 1.5e-179 596.8 3.2 1.6e-179 596.8 1.3 1.6 2 0 0 2 2 2 1 TIP49 C-terminus AAA PF00004.24 AIN97729.1 - 1.2e-08 35.2 1.9 5.4e-06 26.6 0.1 3.1 3 1 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 AIN97729.1 - 1.4e-07 31.6 1.2 0.017 15.2 0.2 3.1 2 1 0 3 3 2 2 AAA domain RuvB_N PF05496.7 AIN97729.1 - 1.6e-07 30.6 1.7 0.00017 20.6 0.0 3.3 2 1 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 AIN97729.1 - 6.8e-06 26.1 0.1 4.2e-05 23.6 0.0 2.2 1 1 0 1 1 1 1 AAA ATPase domain DnaB_C PF03796.10 AIN97729.1 - 1.5e-05 24.0 0.1 2.7e-05 23.2 0.1 1.5 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain AAA_5 PF07728.9 AIN97729.1 - 4.5e-05 23.2 0.3 0.0085 15.8 0.0 3.0 3 0 0 3 3 2 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.16 AIN97729.1 - 5.1e-05 22.5 1.3 0.00094 18.4 0.4 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI FtsK_SpoIIIE PF01580.13 AIN97729.1 - 0.00013 21.5 0.4 0.0063 16.0 0.1 2.4 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_19 PF13245.1 AIN97729.1 - 0.00078 19.1 0.0 0.002 17.8 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain Zeta_toxin PF06414.7 AIN97729.1 - 0.00096 18.2 0.3 0.0024 17.0 0.2 1.6 1 0 0 1 1 1 1 Zeta toxin AAA_25 PF13481.1 AIN97729.1 - 0.0013 18.1 0.0 0.0035 16.7 0.0 1.8 1 0 0 1 1 1 1 AAA domain Sigma54_activat PF00158.21 AIN97729.1 - 0.0034 16.8 0.0 1.2 8.5 0.1 2.6 2 0 0 2 2 2 1 Sigma-54 interaction domain Sigma54_activ_2 PF14532.1 AIN97729.1 - 0.0035 17.3 0.1 0.3 11.1 0.0 3.0 3 0 0 3 3 3 1 Sigma-54 interaction domain CPT PF07931.7 AIN97729.1 - 0.0058 16.2 0.4 0.023 14.3 0.1 2.3 2 1 0 2 2 2 1 Chloramphenicol phosphotransferase-like protein KaiC PF06745.8 AIN97729.1 - 0.0059 15.7 0.2 0.014 14.5 0.2 1.7 1 0 0 1 1 1 1 KaiC AAA_14 PF13173.1 AIN97729.1 - 0.006 16.4 0.0 2.5 7.9 0.0 2.8 2 1 1 3 3 3 1 AAA domain IstB_IS21 PF01695.12 AIN97729.1 - 0.013 14.9 0.2 0.043 13.2 0.1 1.8 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_28 PF13521.1 AIN97729.1 - 0.015 15.2 0.1 0.035 14.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 AIN97729.1 - 0.025 14.2 0.0 0.07 12.7 0.0 1.8 2 0 0 2 2 2 0 NACHT domain DUF2075 PF09848.4 AIN97729.1 - 0.03 13.3 0.0 0.052 12.5 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_17 PF13207.1 AIN97729.1 - 0.033 14.9 0.0 0.13 13.0 0.0 2.1 2 0 0 2 2 1 0 AAA domain AAA_18 PF13238.1 AIN97729.1 - 0.053 13.8 0.0 0.15 12.3 0.0 1.8 2 0 0 2 2 1 0 AAA domain AAA_29 PF13555.1 AIN97729.1 - 0.053 13.0 0.2 0.15 11.5 0.1 1.8 2 0 0 2 2 2 0 P-loop containing region of AAA domain UPF0079 PF02367.12 AIN97729.1 - 0.055 13.1 0.1 0.15 11.7 0.1 1.7 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 ABC_tran PF00005.22 AIN97729.1 - 0.067 13.4 0.2 0.15 12.3 0.1 1.6 1 0 0 1 1 1 0 ABC transporter SUV3_C PF12513.3 AIN97730.1 - 1.1e-11 43.9 0.1 3.5e-11 42.3 0.0 1.9 1 0 0 1 1 1 1 Mitochondrial degradasome RNA helicase subunit C terminal Helicase_C PF00271.26 AIN97730.1 - 1.4e-05 24.8 0.0 3.1e-05 23.7 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 AIN97730.1 - 0.002 17.6 0.0 0.009 15.5 0.0 2.0 1 1 0 1 1 1 1 DEAD/DEAH box helicase Kinesin PF00225.18 AIN97730.1 - 0.072 11.7 0.0 0.11 11.1 0.0 1.2 1 0 0 1 1 1 0 Kinesin motor domain Hydrolase PF00702.21 AIN97731.1 - 1.6e-16 61.4 1.2 4.9e-09 36.9 1.6 3.2 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase HAD PF12710.2 AIN97731.1 - 1.7e-12 47.8 0.0 1.5e-11 44.8 0.0 2.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 AIN97731.1 - 2e-10 40.4 0.0 9.4e-10 38.3 0.0 2.0 2 0 0 2 2 2 1 Putative hydrolase of sodium-potassium ATPase alpha subunit E1-E2_ATPase PF00122.15 AIN97731.1 - 7.9e-08 31.6 4.4 3.3e-06 26.2 0.0 2.9 3 0 0 3 3 3 2 E1-E2 ATPase Hydrolase_3 PF08282.7 AIN97731.1 - 0.001 18.7 0.0 0.0018 17.8 0.0 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 AIN97731.1 - 0.0082 16.3 0.0 0.017 15.3 0.0 1.5 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.1 AIN97731.1 - 0.2 11.5 0.0 0.61 10.0 0.0 1.8 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase Cytochrome-c551 PF10643.4 AIN97732.1 - 0.012 14.9 2.0 0.013 14.8 1.4 1.1 1 0 0 1 1 1 0 Photosystem P840 reaction-centre cytochrome c-551 Tetraspannin PF00335.15 AIN97732.1 - 0.061 12.5 2.8 0.066 12.4 2.0 1.2 1 0 0 1 1 1 0 Tetraspanin family SUR7 PF06687.7 AIN97732.1 - 0.37 10.3 3.9 0.4 10.1 2.7 1.1 1 0 0 1 1 1 0 SUR7/PalI family DUF2244 PF10003.4 AIN97732.1 - 2.7 7.3 5.3 3 7.2 3.7 1.1 1 0 0 1 1 1 0 Integral membrane protein (DUF2244) DUF21 PF01595.15 AIN97733.1 - 1.9e-32 112.0 1.1 3.6e-32 111.1 0.7 1.4 1 0 0 1 1 1 1 Domain of unknown function DUF21 CBS PF00571.23 AIN97733.1 - 6.3e-08 32.2 0.2 0.0016 18.1 0.1 2.6 2 0 0 2 2 2 2 CBS domain cNMP_binding PF00027.24 AIN97733.1 - 0.026 14.3 0.0 0.069 12.9 0.0 1.8 1 1 0 1 1 1 0 Cyclic nucleotide-binding domain Vps52 PF04129.7 AIN97734.1 - 2.1e-14 52.9 5.4 1.4e-12 46.9 3.1 2.2 2 0 0 2 2 2 2 Vps52 / Sac2 family XOO_2897-deam PF14440.1 AIN97734.1 - 0.025 14.2 0.1 10 5.8 0.0 2.7 2 0 0 2 2 2 0 Xanthomonas XOO_2897-like deaminase Tropomyosin_1 PF12718.2 AIN97734.1 - 0.078 12.8 3.2 0.31 10.8 0.7 2.4 1 1 1 2 2 2 0 Tropomyosin like FAD_binding_1 PF00667.15 AIN97735.1 - 1.5e-36 125.9 0.0 1.9e-36 125.5 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.20 AIN97735.1 - 1.1e-23 83.8 0.0 2.2e-23 82.8 0.0 1.6 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.16 AIN97735.1 - 2.2e-16 60.3 0.0 4.5e-16 59.3 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain HGTP_anticodon2 PF12745.2 AIN97735.1 - 0.18 10.8 0.0 0.27 10.3 0.0 1.1 1 0 0 1 1 1 0 Anticodon binding domain of tRNAs WD40 PF00400.27 AIN97736.1 - 1.2e-24 85.1 7.9 3.5e-07 29.8 0.2 6.3 8 0 0 8 8 8 5 WD domain, G-beta repeat Nup160 PF11715.3 AIN97736.1 - 0.08 11.0 0.2 0.28 9.2 0.0 2.0 2 0 0 2 2 2 0 Nucleoporin Nup120/160 DUF2478 PF10649.4 AIN97737.1 - 0.034 13.5 0.1 0.077 12.3 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2478) RRM_1 PF00076.17 AIN97738.1 - 1.2e-11 44.0 0.0 2.4e-11 43.1 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 AIN97738.1 - 5.7e-09 35.8 0.0 9.5e-09 35.1 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) eIF3g PF12353.3 AIN97738.1 - 0.00017 21.5 0.1 0.00036 20.4 0.1 1.6 1 1 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit G Orthopox_C10L PF07020.6 AIN97738.1 - 0.089 13.3 0.1 0.15 12.5 0.0 1.4 1 0 0 1 1 1 0 Orthopoxvirus C10L protein PMP1_2 PF08114.6 AIN97740.1 - 0.26 10.8 1.4 12 5.5 0.0 2.6 2 0 0 2 2 2 0 ATPase proteolipid family CPSase_L_D3 PF02787.14 AIN97741.1 - 0.04 13.6 0.0 0.063 13.0 0.0 1.3 1 0 0 1 1 1 0 Carbamoyl-phosphate synthetase large chain, oligomerisation domain WBS_methylT PF12589.3 AIN97742.1 - 7.9e-11 42.2 11.9 7.9e-11 42.2 8.2 1.9 2 0 0 2 2 2 1 Methyltransferase involved in Williams-Beuren syndrome Methyltransf_11 PF08241.7 AIN97742.1 - 2.7e-08 34.2 0.0 0.0015 18.9 0.0 2.4 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_31 PF13847.1 AIN97742.1 - 8.2e-05 22.2 0.0 0.0042 16.6 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 AIN97742.1 - 0.0004 20.7 0.0 0.0038 17.5 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 AIN97742.1 - 0.00043 20.8 0.1 0.0012 19.4 0.1 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 AIN97742.1 - 0.00058 19.6 0.0 0.001 18.7 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 AIN97742.1 - 0.00091 19.6 0.0 0.13 12.7 0.0 2.7 3 0 0 3 3 3 1 Methyltransferase domain EBV-NA3 PF05009.7 AIN97742.1 - 0.33 10.1 3.4 1.4 8.0 1.9 2.1 2 0 0 2 2 2 0 Epstein-Barr virus nuclear antigen 3 (EBNA-3) Metallophos PF00149.23 AIN97745.1 - 2.8e-20 72.5 0.0 6.4e-16 58.3 0.0 3.2 2 1 0 2 2 2 2 Calcineurin-like phosphoesterase DUF3220 PF11516.3 AIN97745.1 - 0.16 11.9 0.0 0.36 10.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3120) Ribosomal_S19e PF01090.14 AIN97746.1 - 1.2e-45 154.4 0.0 1.3e-45 154.2 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S19e Mrr_N PF14338.1 AIN97746.1 - 0.12 12.4 0.0 0.22 11.6 0.0 1.4 1 0 0 1 1 1 0 Mrr N-terminal domain TPR_2 PF07719.12 AIN97747.1 - 0.072 13.0 0.2 0.072 13.0 0.1 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat Amastin PF07344.6 AIN97748.1 - 6e-53 178.6 11.5 7.5e-53 178.2 8.0 1.1 1 0 0 1 1 1 1 Amastin surface glycoprotein Peptidase_M14 PF00246.19 AIN97749.1 - 7.8e-30 104.4 0.0 1.6e-29 103.4 0.0 1.4 1 0 0 1 1 1 1 Zinc carboxypeptidase AstE_AspA PF04952.9 AIN97749.1 - 0.00096 18.1 0.0 0.0018 17.1 0.0 1.4 1 0 0 1 1 1 1 Succinylglutamate desuccinylase / Aspartoacylase family DUF2817 PF10994.3 AIN97749.1 - 0.046 12.8 0.0 0.08 12.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2817) cNMP_binding PF00027.24 AIN97750.1 - 1.7e-21 75.8 0.1 3.8e-11 42.6 0.0 2.4 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain Cupin_2 PF07883.6 AIN97750.1 - 0.073 12.5 0.0 0.59 9.6 0.0 2.2 2 0 0 2 2 2 0 Cupin domain GTP_EFTU PF00009.22 AIN97750.1 - 0.36 10.2 2.2 0.35 10.2 0.3 1.8 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain Urm1 PF09138.6 AIN97751.1 - 1.7e-25 88.9 0.0 1.9e-25 88.8 0.0 1.0 1 0 0 1 1 1 1 Urm1 (Ubiquitin related modifier) ThiS PF02597.15 AIN97751.1 - 1.5e-06 28.5 0.1 1.7e-06 28.3 0.1 1.2 1 0 0 1 1 1 1 ThiS family TGS PF02824.16 AIN97751.1 - 0.024 14.4 0.5 0.039 13.8 0.1 1.5 2 0 0 2 2 2 0 TGS domain GTP_EFTU PF00009.22 AIN97752.1 - 1.2e-30 106.4 0.1 1.7e-30 105.8 0.1 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 AIN97752.1 - 1.5e-07 31.3 0.0 3.7e-07 30.1 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D2 PF03144.20 AIN97752.1 - 2.6e-06 27.4 1.0 4.7e-06 26.6 0.3 1.8 2 0 0 2 2 2 1 Elongation factor Tu domain 2 GTP_EFTU_D4 PF14578.1 AIN97752.1 - 0.00029 20.4 0.1 0.00063 19.3 0.0 1.5 1 0 0 1 1 1 1 Elongation factor Tu domain 4 SRPRB PF09439.5 AIN97752.1 - 0.00056 19.1 0.4 0.011 14.9 0.1 2.5 2 1 0 2 2 2 1 Signal recognition particle receptor beta subunit PduV-EutP PF10662.4 AIN97752.1 - 0.0015 18.0 0.2 1.8 8.0 0.1 2.5 2 0 0 2 2 2 2 Ethanolamine utilisation - propanediol utilisation Miro PF08477.8 AIN97752.1 - 0.011 16.1 0.0 0.029 14.8 0.0 1.8 1 0 0 1 1 1 0 Miro-like protein ATP_bind_1 PF03029.12 AIN97752.1 - 0.024 14.1 0.1 0.32 10.4 0.0 2.6 2 1 0 2 2 2 0 Conserved hypothetical ATP binding protein Dynamin_N PF00350.18 AIN97752.1 - 0.093 12.5 0.1 9.1 6.0 0.0 2.4 1 1 1 2 2 2 0 Dynamin family Hexapep PF00132.19 AIN97753.1 - 3.4e-12 45.2 11.4 6e-08 31.8 0.6 3.3 2 1 0 3 3 3 2 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 AIN97753.1 - 0.00061 19.2 12.9 0.078 12.5 0.9 3.3 3 2 0 3 3 3 2 Hexapeptide repeat of succinyl-transferase SAS4 PF15460.1 AIN97754.1 - 0.067 13.0 0.0 0.088 12.6 0.0 1.2 1 0 0 1 1 1 0 Something about silencing, SAS, complex subunit 4 Ribosomal_L3 PF00297.17 AIN97755.1 - 1.4e-99 332.8 9.7 1.7e-99 332.4 6.8 1.1 1 0 0 1 1 1 1 Ribosomal protein L3 Ribosomal_L3 PF00297.17 AIN97756.1 - 1.4e-99 332.8 9.7 1.7e-99 332.4 6.8 1.1 1 0 0 1 1 1 1 Ribosomal protein L3 Patatin PF01734.17 AIN97757.1 - 4e-08 33.4 2.1 2.2e-07 30.9 1.5 2.0 1 1 0 1 1 1 1 Patatin-like phospholipase Thioredoxin PF00085.15 AIN97759.1 - 0.011 15.3 0.0 0.019 14.6 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin EF-hand_8 PF13833.1 AIN97761.1 - 1.7e-11 43.5 0.1 1.1e-08 34.5 0.0 2.8 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_1 PF00036.27 AIN97761.1 - 1.5e-09 36.4 0.0 5.3e-05 22.2 0.0 4.5 6 0 0 6 6 6 2 EF hand EF-hand_5 PF13202.1 AIN97761.1 - 4.2e-09 35.3 0.4 0.021 14.1 0.0 5.2 6 0 0 6 6 6 2 EF hand EF-hand_6 PF13405.1 AIN97761.1 - 1.7e-08 33.6 0.1 0.0011 18.6 0.0 5.7 6 1 1 7 7 7 1 EF-hand domain EF-hand_7 PF13499.1 AIN97761.1 - 3e-08 33.6 0.0 0.00054 20.0 0.0 3.9 3 1 0 3 3 3 2 EF-hand domain pair DUF2459 PF09601.5 AIN97762.1 - 0.024 14.3 0.0 0.04 13.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2459) DUF4233 PF14017.1 AIN97762.1 - 3.4 7.6 8.4 0.16 11.9 0.5 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF4233) Spc7 PF08317.6 AIN97763.1 - 0.048 12.3 9.7 0.069 11.8 6.7 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein APG6 PF04111.7 AIN97763.1 - 0.72 8.8 12.3 1 8.3 8.5 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 TMF_DNA_bd PF12329.3 AIN97763.1 - 0.76 9.6 12.2 0.53 10.1 2.9 2.3 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding DivIVA PF05103.8 AIN97763.1 - 1.5 8.8 11.6 2.3 8.2 8.1 1.3 1 0 0 1 1 1 0 DivIVA protein DUF4200 PF13863.1 AIN97763.1 - 5.7 6.8 18.0 8.7 6.3 12.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) ADIP PF11559.3 AIN97763.1 - 6 6.7 17.0 46 3.8 11.8 2.1 1 1 0 1 1 1 0 Afadin- and alpha -actinin-Binding Atg14 PF10186.4 AIN97763.1 - 6.3 5.6 12.9 0.2 10.5 1.3 2.0 1 1 1 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 DivIC PF04977.10 AIN97763.1 - 7.6 6.1 16.2 1.2 8.6 3.7 2.7 1 1 1 2 2 2 0 Septum formation initiator NDK PF00334.14 AIN97764.1 - 4.1e-14 52.5 0.0 1.1e-12 47.9 0.0 2.3 2 1 0 2 2 2 2 Nucleoside diphosphate kinase LRR_6 PF13516.1 AIN97765.1 - 0.0058 16.5 0.2 0.6 10.3 0.0 2.7 2 0 0 2 2 2 1 Leucine Rich repeat LRR_1 PF00560.28 AIN97765.1 - 0.033 14.2 0.2 0.18 11.9 0.0 2.5 2 0 0 2 2 2 0 Leucine Rich Repeat Rhodanese PF00581.15 AIN97767.1 - 1.3e-10 41.6 0.0 2.4e-10 40.7 0.0 1.4 1 0 0 1 1 1 1 Rhodanese-like domain Methyltransf_31 PF13847.1 AIN97767.1 - 0.087 12.4 0.0 0.16 11.5 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Aldolase PF01081.14 AIN97767.1 - 0.14 11.3 0.0 3.4 6.7 0.0 2.1 2 0 0 2 2 2 0 KDPG and KHG aldolase Pkinase PF00069.20 AIN97768.1 - 1e-21 77.3 0.0 3.1e-21 75.6 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain RMP PF14996.1 AIN97769.1 - 7.8e-07 29.1 7.1 7.8e-07 29.1 4.9 3.3 3 1 0 3 3 3 1 Retinal Maintenance Beta_helix PF13229.1 AIN97770.1 - 0.017 14.8 0.0 0.22 11.2 0.0 2.3 2 0 0 2 2 2 0 Right handed beta helix region Adeno_E1B_55K PF01696.12 AIN97770.1 - 0.18 10.2 3.2 0.071 11.5 0.4 1.5 2 0 0 2 2 2 0 Adenovirus EB1 55K protein / large t-antigen Cyt-b5 PF00173.23 AIN97771.1 - 1.3e-07 31.2 0.1 1.8e-07 30.8 0.1 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Mito_carr PF00153.22 AIN97772.1 - 1.3e-45 152.9 5.4 1.8e-21 75.6 0.1 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein Z1 PF10593.4 AIN97773.1 - 0.13 11.4 1.1 0.25 10.5 0.2 1.7 1 1 0 2 2 2 0 Z1 domain SWIM PF04434.12 AIN97773.1 - 2.1 7.9 8.3 0.47 9.9 2.2 2.3 2 0 0 2 2 2 0 SWIM zinc finger DNA_pol_A_exo1 PF01612.15 AIN97774.1 - 1.7e-36 125.3 0.4 3.1e-36 124.4 0.3 1.4 1 0 0 1 1 1 1 3'-5' exonuclease PMC2NT PF08066.7 AIN97774.1 - 1.7e-25 89.1 0.0 1e-24 86.6 0.0 2.4 2 0 0 2 2 2 1 PMC2NT (NUC016) domain HRDC PF00570.18 AIN97774.1 - 1.6e-09 37.3 0.0 3.4e-09 36.2 0.0 1.6 1 0 0 1 1 1 1 HRDC domain 2_5_RNA_ligase2 PF13563.1 AIN97774.1 - 0.11 12.2 1.1 0.29 10.8 0.2 2.2 2 0 0 2 2 2 0 2'-5' RNA ligase superfamily PIP5K PF01504.13 AIN97775.1 - 1.3e-66 224.2 0.0 1.8e-66 223.7 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase AAA_33 PF13671.1 AIN97777.1 - 7.9e-14 51.7 0.0 1.2e-13 51.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain KTI12 PF08433.5 AIN97777.1 - 0.00034 19.8 0.1 0.00046 19.4 0.1 1.2 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_22 PF13401.1 AIN97777.1 - 0.00054 20.0 0.1 0.0011 19.1 0.1 1.4 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 AIN97777.1 - 0.0014 17.7 0.0 0.0025 16.9 0.0 1.6 1 1 0 1 1 1 1 Zeta toxin AAA_17 PF13207.1 AIN97777.1 - 0.0014 19.3 0.0 0.002 18.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.1 AIN97777.1 - 0.0021 17.9 0.0 0.0032 17.3 0.0 1.2 1 0 0 1 1 1 1 AAA domain Arch_ATPase PF01637.13 AIN97777.1 - 0.0035 17.0 0.0 0.0048 16.6 0.0 1.2 1 0 0 1 1 1 1 Archaeal ATPase NEP PF10167.4 AIN97777.1 - 0.026 14.2 0.1 0.054 13.2 0.1 1.5 1 0 0 1 1 1 0 Uncharacterised conserved protein AAA_18 PF13238.1 AIN97777.1 - 0.034 14.4 0.3 0.076 13.3 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.9 AIN97777.1 - 0.047 13.4 0.0 0.1 12.3 0.0 1.6 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) TPT PF03151.11 AIN97778.1 - 7.6e-06 25.6 17.1 7.6e-06 25.6 11.8 3.0 2 2 0 2 2 2 1 Triose-phosphate Transporter family UAA PF08449.6 AIN97778.1 - 0.0014 17.5 28.3 0.0044 15.9 19.6 1.7 1 1 0 1 1 1 1 UAA transporter family EamA PF00892.15 AIN97778.1 - 0.0037 17.3 36.3 0.028 14.4 12.3 2.4 2 0 0 2 2 2 2 EamA-like transporter family zf-CCHC PF00098.18 AIN97780.1 - 0.033 14.1 3.6 0.033 14.1 2.5 3.4 3 0 0 3 3 3 0 Zinc knuckle WW PF00397.21 AIN97780.1 - 0.051 13.4 2.7 0.053 13.4 0.5 2.1 2 0 0 2 2 2 0 WW domain Elf1 PF05129.8 AIN97780.1 - 0.71 9.6 11.3 0.052 13.2 2.1 3.0 2 1 1 3 3 3 0 Transcription elongation factor Elf1 like TmoB PF06234.7 AIN97781.1 - 0.021 14.6 0.0 0.04 13.7 0.0 1.4 1 0 0 1 1 1 0 Toluene-4-monooxygenase system protein B (TmoB) CesT PF05932.8 AIN97783.1 - 2.7e-11 43.3 0.5 6.6e-11 42.0 0.3 1.7 1 0 0 1 1 1 1 Tir chaperone protein (CesT) family ubiquitin PF00240.18 AIN97783.1 - 0.0009 18.5 0.0 0.008 15.5 0.0 2.1 2 0 0 2 2 2 1 Ubiquitin family bZIP_1 PF00170.16 AIN97783.1 - 0.03 14.2 0.1 0.03 14.2 0.0 3.7 3 1 1 4 4 4 0 bZIP transcription factor Rad60-SLD PF11976.3 AIN97783.1 - 0.038 13.6 0.0 0.09 12.4 0.0 1.6 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like Bacillus_HBL PF05791.6 AIN97783.1 - 0.25 10.6 0.7 13 5.0 0.3 2.3 2 0 0 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) DUF1640 PF07798.6 AIN97783.1 - 1 9.4 4.7 2.2 8.3 1.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1640) ADIP PF11559.3 AIN97783.1 - 7.9 6.3 11.3 6.8 6.5 3.2 2.4 1 1 1 3 3 3 0 Afadin- and alpha -actinin-Binding Epimerase PF01370.16 AIN97785.1 - 1.2e-17 64.1 0.0 2.2e-17 63.2 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 AIN97785.1 - 7.7e-12 45.5 0.0 1.5e-11 44.6 0.0 1.5 1 0 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 AIN97785.1 - 3.3e-07 29.3 0.0 6.1e-07 28.4 0.0 1.5 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NmrA PF05368.8 AIN97785.1 - 4.2e-06 26.1 0.0 0.00023 20.5 0.0 2.2 2 0 0 2 2 2 1 NmrA-like family NAD_binding_4 PF07993.7 AIN97785.1 - 0.02 13.8 0.0 0.033 13.1 0.0 1.4 1 0 0 1 1 1 0 Male sterility protein PPR_3 PF13812.1 AIN97786.1 - 0.045 14.0 0.1 0.27 11.6 0.1 2.5 1 0 0 1 1 1 0 Pentatricopeptide repeat domain GCV_H PF01597.14 AIN97787.1 - 0.00015 21.3 0.1 0.00024 20.7 0.0 1.3 1 0 0 1 1 1 1 Glycine cleavage H-protein HA2 PF04408.18 AIN97788.1 - 4.3e-15 55.5 0.4 2.5e-14 53.1 0.0 2.5 2 0 0 2 2 2 1 Helicase associated domain (HA2) Helicase_C PF00271.26 AIN97788.1 - 7.8e-10 38.4 0.0 2.8e-09 36.7 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 AIN97788.1 - 1.6e-08 34.2 0.1 3.3e-08 33.2 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase dsrm PF00035.20 AIN97788.1 - 1.5e-07 31.8 0.0 0.005 17.3 0.0 4.4 4 0 0 4 4 4 1 Double-stranded RNA binding motif AAA_22 PF13401.1 AIN97788.1 - 7.6e-05 22.8 0.1 0.00026 21.1 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.1 AIN97788.1 - 0.011 15.6 0.4 0.18 11.6 0.3 2.5 1 1 0 1 1 1 0 AAA domain KaiC PF06745.8 AIN97788.1 - 0.023 13.8 0.0 0.044 12.9 0.0 1.4 1 0 0 1 1 1 0 KaiC AAA_23 PF13476.1 AIN97788.1 - 0.18 12.1 0.0 0.4 10.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain TPP_enzyme_N PF02776.13 AIN97790.1 - 1.7e-33 115.5 0.3 3.5e-33 114.5 0.0 1.7 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.16 AIN97790.1 - 4.7e-22 78.1 0.0 8.4e-22 77.3 0.0 1.4 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.17 AIN97790.1 - 7.7e-16 58.0 0.1 1.7e-15 57.0 0.0 1.5 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain DXP_synthase_N PF13292.1 AIN97790.1 - 0.025 13.5 0.0 0.036 12.9 0.0 1.2 1 0 0 1 1 1 0 1-deoxy-D-xylulose-5-phosphate synthase XFP_N PF09364.5 AIN97790.1 - 0.048 12.2 0.0 0.079 11.5 0.0 1.2 1 0 0 1 1 1 0 XFP N-terminal domain DRMBL PF07522.9 AIN97791.1 - 4.4e-18 65.3 0.0 8.4e-18 64.4 0.0 1.5 1 0 0 1 1 1 1 DNA repair metallo-beta-lactamase DUF4379 PF14311.1 AIN97792.1 - 2.9e-13 49.4 0.1 5e-13 48.6 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4379) zf-UBP PF02148.14 AIN97793.1 - 3.3e-17 62.3 5.8 1.2e-16 60.5 4.0 1.9 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein Med4 PF10018.4 AIN97793.1 - 0.18 11.1 7.0 0.028 13.8 1.9 1.8 2 0 0 2 2 2 0 Vitamin-D-receptor interacting Mediator subunit 4 Amastin PF07344.6 AIN97794.1 - 3.8e-54 182.4 11.1 4.6e-54 182.2 7.7 1.0 1 0 0 1 1 1 1 Amastin surface glycoprotein Claudin_2 PF13903.1 AIN97794.1 - 0.00058 19.6 11.3 0.00058 19.6 7.8 1.8 1 1 1 2 2 2 1 PMP-22/EMP/MP20/Claudin tight junction DUF1469 PF07332.6 AIN97794.1 - 0.029 14.1 2.7 0.029 14.1 1.9 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1469) DUF4293 PF14126.1 AIN97794.1 - 0.041 13.8 6.6 0.1 12.5 4.6 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4293) Amastin PF07344.6 AIN97795.1 - 8.3e-51 171.6 14.4 9.8e-51 171.4 10.0 1.0 1 0 0 1 1 1 1 Amastin surface glycoprotein Claudin_2 PF13903.1 AIN97795.1 - 0.00089 18.9 12.5 0.00089 18.9 8.6 1.9 2 0 0 2 2 2 1 PMP-22/EMP/MP20/Claudin tight junction Amastin PF07344.6 AIN97796.1 - 6.8e-53 178.4 8.7 8.2e-53 178.1 6.0 1.1 1 0 0 1 1 1 1 Amastin surface glycoprotein Claudin_2 PF13903.1 AIN97796.1 - 0.051 13.2 14.4 0.12 12.0 9.2 2.2 1 1 1 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction PMP22_Claudin PF00822.15 AIN97796.1 - 0.27 10.8 11.6 0.066 12.8 4.0 2.0 1 1 1 2 2 2 0 PMP-22/EMP/MP20/Claudin family Prominin PF05478.6 AIN97796.1 - 0.68 7.3 6.9 1.4 6.3 4.8 1.5 1 0 0 1 1 1 0 Prominin UPF0054 PF02130.12 AIN97798.1 - 1.5e-36 124.8 0.0 1.7e-36 124.6 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized protein family UPF0054 LRR_4 PF12799.2 AIN97799.1 - 0.00028 20.4 3.5 0.19 11.3 0.5 2.8 3 0 0 3 3 3 2 Leucine Rich repeats (2 copies) LRR_6 PF13516.1 AIN97799.1 - 0.018 15.0 12.1 3.1 8.1 0.2 4.7 5 0 0 5 5 5 0 Leucine Rich repeat LRR_1 PF00560.28 AIN97799.1 - 0.14 12.2 8.7 18 5.8 0.1 4.7 4 0 0 4 4 4 0 Leucine Rich Repeat LRR_8 PF13855.1 AIN97799.1 - 3.3 7.5 11.3 0.48 10.2 1.9 2.9 2 1 1 3 3 3 0 Leucine rich repeat p450 PF00067.17 AIN97801.1 - 5.4e-60 203.2 0.0 7.5e-60 202.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 DUF1477 PF07346.6 AIN97801.1 - 0.0023 17.9 0.1 0.0047 16.9 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1477) AAA PF00004.24 AIN97803.1 - 9.5e-35 119.6 0.0 2.3e-34 118.4 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 AIN97803.1 - 4.3e-05 24.3 0.0 0.00016 22.4 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.1 AIN97803.1 - 8.9e-05 22.6 0.0 0.007 16.5 0.0 2.7 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 AIN97803.1 - 0.00014 21.5 1.6 0.0013 18.4 0.0 3.0 3 0 0 3 3 2 1 Part of AAA domain AAA_5 PF07728.9 AIN97803.1 - 0.00022 20.9 0.0 0.0011 18.7 0.0 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) NACHT PF05729.7 AIN97803.1 - 0.00054 19.6 0.2 0.42 10.2 0.0 2.8 1 1 1 2 2 2 2 NACHT domain RuvB_N PF05496.7 AIN97803.1 - 0.0011 18.1 0.0 0.003 16.6 0.0 1.7 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 AIN97803.1 - 0.0012 18.9 2.2 0.0046 16.9 0.2 2.7 2 1 0 2 2 2 1 AAA ATPase domain AAA_33 PF13671.1 AIN97803.1 - 0.0024 17.7 0.1 0.0068 16.2 0.1 2.0 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.12 AIN97803.1 - 0.004 16.5 1.0 0.017 14.5 0.1 2.2 2 1 0 2 2 2 1 IstB-like ATP binding protein TIP49 PF06068.8 AIN97803.1 - 0.0042 15.8 0.0 0.01 14.5 0.0 1.6 1 1 1 2 2 2 1 TIP49 C-terminus ResIII PF04851.10 AIN97803.1 - 0.02 14.7 0.0 0.043 13.6 0.0 1.5 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_14 PF13173.1 AIN97803.1 - 0.021 14.7 0.0 0.046 13.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.1 AIN97803.1 - 0.026 14.0 0.0 0.046 13.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.16 AIN97803.1 - 0.068 12.3 0.0 0.23 10.5 0.0 1.9 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_25 PF13481.1 AIN97803.1 - 0.074 12.4 0.0 0.15 11.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain Vps4_C PF09336.5 AIN97803.1 - 0.075 12.9 0.0 0.22 11.4 0.0 1.7 1 0 0 1 1 1 0 Vps4 C terminal oligomerisation domain RNA_helicase PF00910.17 AIN97803.1 - 0.18 12.0 0.0 1.2 9.3 0.0 2.1 2 0 0 2 2 2 0 RNA helicase AAA_2 PF07724.9 AIN97803.1 - 0.21 11.4 0.0 0.63 9.9 0.0 1.8 2 0 0 2 2 2 0 AAA domain (Cdc48 subfamily) TLC PF03219.9 AIN97804.1 - 0.15 10.5 0.0 0.18 10.2 0.0 1.1 1 0 0 1 1 1 0 TLC ATP/ADP transporter Aldose_epim PF01263.15 AIN97805.1 - 1.8e-31 109.4 0.0 2.4e-31 108.9 0.0 1.2 1 0 0 1 1 1 1 Aldose 1-epimerase HECT PF00632.20 AIN97806.1 - 1.4e-07 30.9 0.0 0.011 14.9 0.0 2.1 2 0 0 2 2 2 2 HECT-domain (ubiquitin-transferase) HECT PF00632.20 AIN97807.1 - 6.6e-06 25.5 0.2 1e-05 24.8 0.1 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Lactamase_B PF00753.22 AIN97808.1 - 5.4e-12 45.7 2.2 1.4e-11 44.3 0.0 2.4 2 1 0 2 2 2 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 AIN97808.1 - 0.014 14.9 0.0 0.028 13.9 0.0 1.5 1 0 0 1 1 1 0 Beta-lactamase superfamily domain Beta-Casp PF10996.3 AIN97809.1 - 3.5e-32 111.0 0.0 7.7e-32 109.8 0.0 1.6 1 0 0 1 1 1 1 Beta-Casp domain Lactamase_B PF00753.22 AIN97809.1 - 8.2e-19 68.0 0.1 1.4e-18 67.2 0.1 1.3 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily CPSF73-100_C PF11718.3 AIN97809.1 - 6.9e-12 45.1 0.1 1.2e-11 44.4 0.1 1.4 1 0 0 1 1 1 1 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term Lactamase_B_2 PF12706.2 AIN97809.1 - 2.2e-10 40.3 0.0 5.1e-10 39.2 0.0 1.6 1 0 0 1 1 1 1 Beta-lactamase superfamily domain RMMBL PF07521.7 AIN97809.1 - 1.8e-08 34.0 0.2 4.8e-08 32.7 0.1 1.8 1 0 0 1 1 1 1 RNA-metabolising metallo-beta-lactamase Lactamase_B_3 PF13483.1 AIN97809.1 - 0.00015 21.5 0.0 0.00042 20.0 0.0 1.7 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Topoisom_I_N PF02919.10 AIN97810.1 - 3.8e-93 310.7 1.1 3.8e-93 310.7 0.8 3.5 2 1 1 3 3 3 1 Eukaryotic DNA topoisomerase I, DNA binding fragment Topoisom_I PF01028.15 AIN97810.1 - 1.4e-83 279.5 2.9 1.4e-83 279.5 2.0 1.9 2 0 0 2 2 2 1 Eukaryotic DNA topoisomerase I, catalytic core LRR_9 PF14580.1 AIN97811.1 - 1.5e-05 24.6 0.1 2.6e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 Leucine-rich repeat LRR_4 PF12799.2 AIN97811.1 - 0.00032 20.2 2.2 0.0031 17.0 0.0 2.8 3 0 0 3 3 3 1 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 AIN97811.1 - 0.00093 18.9 0.6 0.0031 17.2 0.4 1.9 1 0 0 1 1 1 1 Leucine rich repeat TMF_TATA_bd PF12325.3 AIN97811.1 - 0.14 11.9 0.0 0.43 10.3 0.0 1.8 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding LRR_1 PF00560.28 AIN97811.1 - 4.3 7.7 5.1 26 5.3 0.0 4.0 3 1 0 3 3 3 0 Leucine Rich Repeat zf-RanBP PF00641.13 AIN97812.1 - 2.1e-05 23.5 2.6 2.1e-05 23.5 1.8 1.8 2 0 0 2 2 2 1 Zn-finger in Ran binding protein and others DUF35_N PF12172.3 AIN97812.1 - 0.088 12.7 3.3 0.35 10.8 2.3 2.1 1 0 0 1 1 1 0 Rubredoxin-like zinc ribbon domain (DUF35_N) Amidinotransf PF02274.12 AIN97813.1 - 8.8e-13 47.9 0.0 1.2e-12 47.5 0.0 1.3 1 1 0 1 1 1 1 Amidinotransferase LRR_6 PF13516.1 AIN97814.1 - 0.00084 19.1 0.6 0.0074 16.2 0.0 2.6 1 1 1 2 2 2 1 Leucine Rich repeat LRR_4 PF12799.2 AIN97814.1 - 0.04 13.5 0.9 0.1 12.2 0.6 1.7 1 0 0 1 1 1 0 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 AIN97814.1 - 0.17 12.0 0.8 5.5 7.4 0.0 3.0 2 0 0 2 2 2 0 Leucine Rich Repeat TPR_12 PF13424.1 AIN97815.1 - 6.4e-37 125.3 34.1 2.1e-09 37.1 0.8 5.9 2 2 4 6 6 6 6 Tetratricopeptide repeat TPR_10 PF13374.1 AIN97815.1 - 1.3e-22 78.9 23.4 3.8e-06 26.6 0.0 7.2 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_11 PF13414.1 AIN97815.1 - 4.5e-13 48.6 16.5 3.2e-07 29.8 0.0 5.4 3 2 1 5 5 5 3 TPR repeat TPR_8 PF13181.1 AIN97815.1 - 1.8e-12 46.0 10.7 0.00041 19.9 0.1 7.1 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_14 PF13428.1 AIN97815.1 - 0.00076 19.9 24.9 0.69 10.7 0.1 7.2 6 2 3 9 9 6 1 Tetratricopeptide repeat TPR_17 PF13431.1 AIN97815.1 - 0.00085 19.3 3.4 60 4.2 0.0 6.3 6 0 0 6 6 6 0 Tetratricopeptide repeat DUF2225 PF09986.4 AIN97815.1 - 0.0011 18.4 0.2 0.87 8.9 0.0 3.3 3 1 0 3 3 3 1 Uncharacterized protein conserved in bacteria (DUF2225) Drf_FH3 PF06367.11 AIN97815.1 - 0.0093 15.3 0.0 0.018 14.4 0.0 1.4 1 0 0 1 1 1 1 Diaphanous FH3 Domain TPR_7 PF13176.1 AIN97815.1 - 0.011 15.4 18.1 3.1 7.8 0.1 7.1 8 0 0 8 8 6 0 Tetratricopeptide repeat Tcf25 PF04910.9 AIN97815.1 - 0.011 14.6 0.6 3.8 6.3 0.0 2.3 2 0 0 2 2 2 0 Transcriptional repressor TCF25 Rapsyn_N PF10579.4 AIN97815.1 - 0.04 13.7 1.7 6.8 6.5 0.0 3.6 2 1 2 4 4 4 0 Rapsyn N-terminal myristoylation and linker region TPR_16 PF13432.1 AIN97815.1 - 0.083 13.5 26.3 2.4 8.9 0.1 6.4 4 1 3 7 7 7 0 Tetratricopeptide repeat TPR_4 PF07721.9 AIN97815.1 - 0.14 12.6 0.5 0.14 12.6 0.3 5.2 6 0 0 6 6 4 0 Tetratricopeptide repeat DUF1771 PF08590.5 AIN97815.1 - 0.28 11.2 9.2 0.51 10.3 0.2 3.6 4 0 0 4 4 4 0 Domain of unknown function (DUF1771) TPR_1 PF00515.23 AIN97815.1 - 0.65 9.7 19.1 7.1 6.4 0.0 6.3 6 0 0 6 6 6 0 Tetratricopeptide repeat ATG16 PF08614.6 AIN97815.1 - 0.7 9.6 4.7 4.6 7.0 0.1 3.0 3 0 0 3 3 3 0 Autophagy protein 16 (ATG16) TPR_2 PF07719.12 AIN97815.1 - 1.2 9.2 23.6 1.6 8.8 0.4 6.7 8 0 0 8 8 8 0 Tetratricopeptide repeat TPR_19 PF14559.1 AIN97815.1 - 1.8 8.9 10.4 0.64 10.4 1.3 4.2 4 1 0 5 5 5 0 Tetratricopeptide repeat TIP49 PF06068.8 AIN97816.1 - 1.7e-183 609.8 1.7 2e-183 609.5 1.2 1.0 1 0 0 1 1 1 1 TIP49 C-terminus RuvB_N PF05496.7 AIN97816.1 - 1.1e-12 47.5 1.1 1.4e-07 30.7 0.0 2.9 2 1 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus AAA PF00004.24 AIN97816.1 - 1.2e-11 44.9 0.9 4e-07 30.3 0.0 3.0 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 AIN97816.1 - 8e-07 29.2 0.1 0.04 14.0 0.0 2.6 2 1 0 2 2 2 2 AAA domain AAA_16 PF13191.1 AIN97816.1 - 6.8e-06 26.1 0.0 0.00063 19.7 0.0 2.3 1 1 0 1 1 1 1 AAA ATPase domain Mg_chelatase PF01078.16 AIN97816.1 - 0.00013 21.2 0.2 0.0074 15.4 0.0 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 AIN97816.1 - 0.00026 20.7 0.1 0.093 12.4 0.0 2.5 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_25 PF13481.1 AIN97816.1 - 0.0011 18.3 0.0 0.002 17.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 AIN97816.1 - 0.0014 18.3 0.5 0.0041 16.8 0.2 1.9 1 1 1 2 2 2 1 Part of AAA domain AAA_33 PF13671.1 AIN97816.1 - 0.0036 17.1 0.0 0.018 14.9 0.0 2.1 3 0 0 3 3 2 1 AAA domain IstB_IS21 PF01695.12 AIN97816.1 - 0.0046 16.3 0.3 0.028 13.8 0.0 2.3 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_17 PF13207.1 AIN97816.1 - 0.0064 17.3 0.0 0.026 15.3 0.0 2.1 2 1 0 2 2 2 1 AAA domain AAA_18 PF13238.1 AIN97816.1 - 0.01 16.1 0.1 0.11 12.7 0.0 2.5 2 1 0 2 2 2 0 AAA domain AAA_14 PF13173.1 AIN97816.1 - 0.011 15.6 0.0 2.8 7.8 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.1 AIN97816.1 - 0.011 15.6 0.0 0.027 14.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain MinE PF03776.9 AIN97816.1 - 0.03 13.8 0.2 0.073 12.5 0.1 1.6 1 0 0 1 1 1 0 Septum formation topological specificity factor MinE AAA_11 PF13086.1 AIN97816.1 - 0.041 13.4 0.1 0.08 12.4 0.0 1.6 1 1 0 1 1 1 0 AAA domain DnaB_C PF03796.10 AIN97816.1 - 0.06 12.2 0.0 0.12 11.2 0.0 1.5 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain ResIII PF04851.10 AIN97816.1 - 0.096 12.5 0.3 2.4 7.9 0.0 2.4 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit SET PF00856.23 AIN97817.1 - 0.013 15.8 0.0 0.018 15.3 0.0 1.5 1 1 0 1 1 1 0 SET domain AAA PF00004.24 AIN97818.1 - 4.6e-47 159.5 0.0 1.5e-37 128.7 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) PEX-1N PF09262.6 AIN97818.1 - 7.3e-21 74.0 0.1 1.9e-20 72.6 0.1 1.8 1 0 0 1 1 1 1 Peroxisome biogenesis factor 1, N-terminal AAA_16 PF13191.1 AIN97818.1 - 5.3e-11 42.8 3.5 0.001 19.1 0.0 5.3 4 2 1 5 5 4 2 AAA ATPase domain AAA_22 PF13401.1 AIN97818.1 - 4.4e-09 36.5 0.1 0.0068 16.5 0.0 3.2 2 1 1 3 3 3 2 AAA domain AAA_33 PF13671.1 AIN97818.1 - 1.3e-06 28.3 0.0 0.012 15.5 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_14 PF13173.1 AIN97818.1 - 2.5e-06 27.4 0.0 0.00059 19.7 0.0 2.4 2 0 0 2 2 2 1 AAA domain DUF815 PF05673.8 AIN97818.1 - 3.9e-06 25.9 0.0 0.0016 17.4 0.0 2.6 2 1 0 2 2 2 1 Protein of unknown function (DUF815) ATP-synt_ab PF00006.20 AIN97818.1 - 5.1e-06 26.1 0.1 0.031 13.7 0.0 3.2 3 0 0 3 3 3 2 ATP synthase alpha/beta family, nucleotide-binding domain AAA_17 PF13207.1 AIN97818.1 - 1.5e-05 25.7 0.0 0.0065 17.2 0.0 2.6 2 0 0 2 2 2 1 AAA domain Arch_ATPase PF01637.13 AIN97818.1 - 2.2e-05 24.2 0.1 0.18 11.4 0.0 3.2 2 1 1 3 3 3 1 Archaeal ATPase T2SE PF00437.15 AIN97818.1 - 4.6e-05 22.4 0.0 0.079 11.8 0.0 2.5 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_28 PF13521.1 AIN97818.1 - 6.7e-05 22.9 0.0 0.041 13.8 0.0 2.7 3 0 0 3 3 2 1 AAA domain AAA_25 PF13481.1 AIN97818.1 - 0.00011 21.7 2.0 2.5 7.4 0.0 4.9 5 0 0 5 5 5 1 AAA domain AAA_29 PF13555.1 AIN97818.1 - 0.00012 21.5 0.0 0.16 11.5 0.0 2.8 2 0 0 2 2 2 1 P-loop containing region of AAA domain RNA_helicase PF00910.17 AIN97818.1 - 0.00022 21.3 0.0 0.075 13.2 0.0 3.0 3 0 0 3 3 2 1 RNA helicase IstB_IS21 PF01695.12 AIN97818.1 - 0.00022 20.6 0.0 0.17 11.2 0.0 2.8 3 0 0 3 3 2 1 IstB-like ATP binding protein ABC_tran PF00005.22 AIN97818.1 - 0.00023 21.4 0.0 0.24 11.7 0.0 2.9 3 0 0 3 3 2 1 ABC transporter AAA_5 PF07728.9 AIN97818.1 - 0.00035 20.2 0.0 0.11 12.1 0.0 3.1 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 AIN97818.1 - 0.00038 20.4 0.0 0.00099 19.0 0.0 1.7 2 0 0 2 2 1 1 AAA domain (Cdc48 subfamily) FtsK_SpoIIIE PF01580.13 AIN97818.1 - 0.00044 19.7 0.0 0.0062 16.0 0.0 2.7 2 0 0 2 2 2 1 FtsK/SpoIIIE family Vps4_C PF09336.5 AIN97818.1 - 0.00091 19.0 0.0 0.0039 17.0 0.0 2.0 2 0 0 2 2 1 1 Vps4 C terminal oligomerisation domain DUF258 PF03193.11 AIN97818.1 - 0.0012 18.0 0.0 0.92 8.6 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 NACHT PF05729.7 AIN97818.1 - 0.0016 18.1 1.6 1.6 8.3 0.0 4.2 3 1 0 4 4 4 1 NACHT domain Zeta_toxin PF06414.7 AIN97818.1 - 0.0023 17.0 0.0 1.5 7.8 0.0 2.4 2 0 0 2 2 2 2 Zeta toxin Sigma54_activat PF00158.21 AIN97818.1 - 0.0052 16.2 0.1 3.1 7.2 0.0 3.0 3 0 0 3 3 3 1 Sigma-54 interaction domain Miro PF08477.8 AIN97818.1 - 0.0061 17.0 0.0 0.63 10.5 0.0 2.5 2 0 0 2 2 2 1 Miro-like protein AAA_23 PF13476.1 AIN97818.1 - 0.0067 16.7 0.1 2.5 8.3 0.0 2.2 2 0 0 2 2 2 1 AAA domain Mg_chelatase PF01078.16 AIN97818.1 - 0.011 14.9 0.0 3.8 6.6 0.0 2.4 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI Bac_DnaA PF00308.13 AIN97818.1 - 0.017 14.8 0.0 3.4 7.2 0.0 3.0 3 0 0 3 3 3 0 Bacterial dnaA protein Rad17 PF03215.10 AIN97818.1 - 0.019 13.6 0.0 0.92 8.1 0.0 2.2 2 0 0 2 2 2 0 Rad17 cell cycle checkpoint protein Sigma54_activ_2 PF14532.1 AIN97818.1 - 0.02 14.9 0.0 1.5 8.8 0.0 2.7 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_24 PF13479.1 AIN97818.1 - 0.032 13.8 0.1 1.6 8.2 0.0 2.9 3 0 0 3 3 3 0 AAA domain AAA_10 PF12846.2 AIN97818.1 - 0.039 13.3 0.1 11 5.3 0.0 2.6 2 0 0 2 2 2 0 AAA-like domain TrwB_AAD_bind PF10412.4 AIN97818.1 - 0.049 12.2 0.0 0.69 8.4 0.0 2.1 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain MobB PF03205.9 AIN97818.1 - 0.072 12.7 0.3 2.6 7.7 0.1 2.5 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_18 PF13238.1 AIN97818.1 - 0.076 13.3 0.0 1.1 9.5 0.0 2.3 2 0 0 2 2 2 0 AAA domain KAP_NTPase PF07693.9 AIN97818.1 - 0.3 10.0 0.0 0.67 8.8 0.0 1.6 2 0 0 2 2 1 0 KAP family P-loop domain Septin PF00735.13 AIN97818.1 - 0.36 9.7 0.1 8.7 5.2 0.0 2.2 2 0 0 2 2 2 0 Septin zf-H2C2 PF09337.5 AIN97818.1 - 3.2 7.2 5.1 1.6 8.1 0.0 2.6 3 0 0 3 3 2 0 His(2)-Cys(2) zinc finger DUF3140 PF11338.3 AIN97819.1 - 0.048 13.7 0.0 0.13 12.3 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3140) LicD PF04991.8 AIN97820.1 - 1.5e-13 51.3 0.1 8.5e-07 29.2 0.1 2.1 1 1 0 2 2 2 2 LicD family Deltaretro_Tax PF05599.6 AIN97820.1 - 0.0045 17.2 0.0 0.021 15.1 0.0 2.0 2 0 0 2 2 2 1 Deltaretrovirus Tax protein PDCD2_C PF04194.8 AIN97821.1 - 6.9e-21 74.5 0.6 1.3e-20 73.6 0.0 1.7 2 0 0 2 2 2 1 Programmed cell death protein 2, C-terminal putative domain Elf1 PF05129.8 AIN97821.1 - 0.031 13.9 0.7 0.2 11.3 0.1 2.2 2 0 0 2 2 2 0 Transcription elongation factor Elf1 like Ank PF00023.25 AIN97822.1 - 3.5e-29 99.1 0.4 1e-07 31.3 0.0 5.4 5 0 0 5 5 5 5 Ankyrin repeat Ank_2 PF12796.2 AIN97822.1 - 5.7e-29 100.2 0.9 7.3e-15 55.0 0.0 3.3 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.1 AIN97822.1 - 3.9e-20 71.8 0.8 1.5e-06 28.5 0.0 4.6 2 2 3 5 5 5 5 Ankyrin repeats (many copies) Ank_5 PF13857.1 AIN97822.1 - 8.2e-20 70.3 4.1 1.2e-05 25.3 0.1 4.4 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 AIN97822.1 - 4e-19 66.7 0.6 0.00012 21.9 0.0 5.4 5 0 0 5 5 5 4 Ankyrin repeat Integrin_beta PF00362.13 AIN97824.1 - 0.44 9.3 2.1 14 4.4 0.0 2.9 3 0 0 3 3 3 0 Integrin, beta chain PI3_PI4_kinase PF00454.22 AIN97825.1 - 3.8e-36 124.7 0.2 1.4e-34 119.6 0.0 2.5 2 1 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase PfkB PF00294.19 AIN97826.1 - 4.7e-41 140.8 0.2 2.5e-40 138.4 0.1 1.9 1 1 0 1 1 1 1 pfkB family carbohydrate kinase Complex1_LYR PF05347.10 AIN97827.1 - 5.6e-12 45.2 0.8 9.1e-12 44.5 0.5 1.3 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 AIN97827.1 - 5.2e-09 36.1 0.5 8.7e-09 35.4 0.4 1.3 1 0 0 1 1 1 1 Complex1_LYR-like DUF3336 PF11815.3 AIN97828.1 - 1.2e-25 89.6 0.0 2.1e-25 88.8 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3336) Patatin PF01734.17 AIN97828.1 - 2.9e-08 33.8 2.6 1.1e-07 31.9 1.8 1.9 1 1 0 1 1 1 1 Patatin-like phospholipase Metallophos PF00149.23 AIN97829.1 - 0.00032 20.1 0.1 0.0019 17.5 0.0 2.1 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase ChAPs PF09295.5 AIN97829.1 - 0.13 10.9 0.0 0.2 10.3 0.0 1.1 1 0 0 1 1 1 0 ChAPs (Chs5p-Arf1p-binding proteins) DUF2975 PF11188.3 AIN97830.1 - 0.028 14.1 1.4 0.058 13.1 1.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2975) zf-U1 PF06220.7 AIN97830.1 - 0.14 11.7 0.3 0.14 11.7 0.2 1.6 2 0 0 2 2 2 0 U1 zinc finger DUF2149 PF09919.4 AIN97831.1 - 0.076 13.1 0.3 0.12 12.4 0.0 1.7 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2149) DctQ PF04290.7 AIN97831.1 - 0.38 10.5 4.1 0.45 10.2 2.8 1.1 1 0 0 1 1 1 0 Tripartite ATP-independent periplasmic transporters, DctQ component CcoS PF03597.10 AIN97831.1 - 1.2 8.6 3.4 0.31 10.5 0.2 1.5 2 0 0 2 2 2 0 Cytochrome oxidase maturation protein cbb3-type Ribosomal_L21e PF01157.13 AIN97832.1 - 2e-35 120.5 2.9 2.8e-35 120.1 2.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L21e EMP70 PF02990.11 AIN97833.1 - 5.8e-117 391.3 4.6 7.2e-117 390.9 3.2 1.1 1 0 0 1 1 1 1 Endomembrane protein 70 Pox_T4_C PF04490.7 AIN97833.1 - 0.11 12.2 0.1 0.26 11.0 0.1 1.6 1 1 0 1 1 1 0 Poxvirus T4 protein, C terminus ATP-synt_ab PF00006.20 AIN97834.1 - 2e-108 360.8 0.0 3.2e-108 360.1 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 AIN97834.1 - 9.1e-24 84.1 0.2 1.5e-23 83.4 0.2 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 AIN97834.1 - 4.7e-14 52.3 1.7 4.7e-14 52.3 1.2 2.7 3 0 0 3 3 3 1 ATP synthase alpha/beta family, beta-barrel domain DUF2737 PF10930.3 AIN97834.1 - 0.024 14.2 0.1 4.9 6.8 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF2737) AAA_14 PF13173.1 AIN97834.1 - 0.12 12.2 0.0 0.3 10.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_31 PF13614.1 AIN97834.1 - 0.13 12.2 0.0 0.28 11.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain Ribosomal_L13 PF00572.13 AIN97835.1 - 5e-30 104.1 0.0 6.3e-30 103.8 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L13 Ins_P5_2-kin PF06090.7 AIN97837.1 - 4.9e-19 68.5 0.0 7.1e-19 67.9 0.0 1.3 1 0 0 1 1 1 1 Inositol-pentakisphosphate 2-kinase CDtoxinA PF03498.9 AIN97837.1 - 0.39 10.0 1.9 4.8 6.5 0.1 2.7 2 1 1 3 3 3 0 Cytolethal distending toxin A/C family DUF2939 PF11159.3 AIN97838.1 - 0.1 12.7 1.6 0.23 11.6 1.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2939) DUF3482 PF11981.3 AIN97838.1 - 0.76 8.9 8.4 1.1 8.4 5.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3482) Alb1 PF09135.6 AIN97838.1 - 5.8 7.5 9.7 0.41 11.2 1.2 2.2 1 1 1 2 2 2 0 Alb1 DUF501 PF04417.7 AIN97839.1 - 1.6e-33 115.4 0.2 2.7e-33 114.7 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF501) Aminotran_1_2 PF00155.16 AIN97841.1 - 1.2e-44 152.7 0.0 1.5e-44 152.4 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II KH_5 PF13184.1 AIN97841.1 - 0.039 13.7 0.5 4 7.2 0.1 2.4 2 0 0 2 2 2 0 NusA-like KH domain LIM PF00412.17 AIN97843.1 - 0.0057 16.7 7.6 0.02 14.9 5.3 2.0 1 0 0 1 1 1 1 LIM domain C1_3 PF07649.7 AIN97843.1 - 0.097 12.7 0.4 0.097 12.7 0.3 2.9 3 0 0 3 3 3 0 C1-like domain zf-HYPF PF07503.7 AIN97843.1 - 0.11 11.8 9.5 0.35 10.3 3.0 3.2 3 0 0 3 3 3 0 HypF finger DUF515 PF04415.7 AIN97843.1 - 0.29 9.3 0.3 0.43 8.7 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF515) Actin PF00022.14 AIN97844.1 - 3.6e-39 134.2 0.0 5e-38 130.5 0.0 2.0 1 1 0 1 1 1 1 Actin PGM_PMM_I PF02878.11 AIN97846.1 - 9.1e-36 122.3 0.1 1.8e-35 121.4 0.0 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_II PF02879.11 AIN97846.1 - 4.8e-20 71.8 0.0 1.1e-19 70.6 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_III PF02880.11 AIN97846.1 - 9e-13 48.2 0.1 4.5e-12 46.0 0.1 2.2 3 0 0 3 3 3 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_IV PF00408.15 AIN97846.1 - 0.00024 21.0 0.0 0.00073 19.4 0.0 1.8 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain WD40 PF00400.27 AIN97847.1 - 0.047 13.5 0.1 1.5 8.8 0.0 3.1 2 0 0 2 2 2 0 WD domain, G-beta repeat PQQ_3 PF13570.1 AIN97847.1 - 0.34 11.2 6.1 0.46 10.8 0.3 3.7 3 0 0 3 3 3 0 PQQ-like domain Ribosomal_L14 PF00238.14 AIN97850.1 - 2.2e-12 46.7 0.0 4e-12 45.9 0.0 1.4 2 0 0 2 2 2 1 Ribosomal protein L14p/L23e K_channel_TID PF07941.6 AIN97850.1 - 0.2 11.9 1.2 0.3 11.3 0.1 1.8 2 0 0 2 2 2 0 Potassium channel Kv1.4 tandem inactivation domain TPR_11 PF13414.1 AIN97851.1 - 1.2e-12 47.3 7.6 4.5e-06 26.2 2.3 3.7 2 1 2 4 4 4 3 TPR repeat TPR_1 PF00515.23 AIN97851.1 - 1.8e-07 30.4 7.9 0.041 13.5 0.0 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.12 AIN97851.1 - 2.9e-06 26.7 10.1 0.077 12.9 0.1 4.0 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_12 PF13424.1 AIN97851.1 - 0.0003 20.6 6.3 0.065 13.1 0.8 3.1 2 1 1 3 3 3 2 Tetratricopeptide repeat DUF2464 PF10240.4 AIN97851.1 - 0.02 14.2 0.0 0.029 13.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2464) TPR_19 PF14559.1 AIN97851.1 - 0.02 15.2 0.2 3.3 8.0 0.0 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.1 AIN97851.1 - 0.024 15.3 3.0 2 9.1 0.1 2.6 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.1 AIN97851.1 - 0.044 13.5 5.4 9 6.3 0.7 3.8 3 1 0 3 3 3 0 Tetratricopeptide repeat Apc3 PF12895.2 AIN97851.1 - 0.045 13.8 7.9 0.21 11.7 3.4 2.9 2 1 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.1 AIN97851.1 - 0.05 13.4 0.4 8 6.4 0.0 2.8 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.1 AIN97851.1 - 0.074 12.8 0.0 0.72 9.8 0.0 2.6 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.1 AIN97851.1 - 0.55 11.0 1.9 42 5.1 0.1 3.0 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.1 AIN97851.1 - 0.76 10.3 3.1 18 6.0 0.3 3.3 3 1 0 3 3 3 0 Tetratricopeptide repeat DUF745 PF05335.8 AIN97852.1 - 8.1e-05 22.2 11.3 0.0027 17.2 3.6 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF745) IncA PF04156.9 AIN97852.1 - 0.0006 19.4 1.9 0.0006 19.4 1.3 1.7 2 0 0 2 2 2 1 IncA protein Atg14 PF10186.4 AIN97852.1 - 0.0015 17.5 3.9 0.0024 16.8 2.7 1.4 1 0 0 1 1 1 1 UV radiation resistance protein and autophagy-related subunit 14 TPR_MLP1_2 PF07926.7 AIN97852.1 - 0.0028 17.4 3.7 0.011 15.5 2.4 2.1 1 1 0 1 1 1 1 TPR/MLP1/MLP2-like protein Myosin_tail_1 PF01576.14 AIN97852.1 - 0.0029 15.4 11.8 0.024 12.3 5.0 2.0 2 0 0 2 2 2 2 Myosin tail ERM PF00769.14 AIN97852.1 - 0.0084 15.6 3.6 0.014 14.9 2.5 1.3 1 0 0 1 1 1 1 Ezrin/radixin/moesin family Dfp1_Him1_M PF08630.5 AIN97852.1 - 0.077 12.7 0.2 0.22 11.3 0.0 1.7 2 1 0 2 2 2 0 Dfp1/Him1, central region Sec2p PF06428.6 AIN97852.1 - 0.098 12.5 4.5 0.29 10.9 3.1 1.8 1 0 0 1 1 1 0 GDP/GTP exchange factor Sec2p EMP24_GP25L PF01105.19 AIN97852.1 - 0.099 12.3 0.1 8.9 5.9 0.3 2.1 2 0 0 2 2 2 0 emp24/gp25L/p24 family/GOLD DUF2951 PF11166.3 AIN97852.1 - 0.12 12.2 6.4 3.5 7.5 1.9 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF2951) Spc7 PF08317.6 AIN97852.1 - 0.21 10.2 5.4 0.11 11.0 1.7 1.8 2 0 0 2 2 2 0 Spc7 kinetochore protein CDC37_N PF03234.9 AIN97852.1 - 0.35 11.1 2.2 6.9 6.9 1.7 2.1 2 1 1 3 3 3 0 Cdc37 N terminal kinase binding CENP-H PF05837.7 AIN97852.1 - 0.35 11.0 7.1 7.8 6.7 2.0 2.6 2 1 1 3 3 3 0 Centromere protein H (CENP-H) ADIP PF11559.3 AIN97852.1 - 1.1 9.1 12.6 1.1 9.1 5.4 2.2 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding HPPK PF01288.15 AIN97852.1 - 1.4 8.6 4.2 6.3 6.5 0.1 2.9 2 1 1 3 3 3 0 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) Spc24 PF08286.6 AIN97852.1 - 1.4 8.5 5.0 0.9 9.2 1.4 2.0 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 Occludin_ELL PF07303.8 AIN97852.1 - 2.7 8.7 5.6 2.4 8.9 2.2 2.2 2 1 0 2 2 2 0 Occludin homology domain Macoilin PF09726.4 AIN97852.1 - 7.1 4.7 9.3 2.6 6.2 4.8 1.4 2 0 0 2 2 2 0 Transmembrane protein MIP PF00230.15 AIN97854.1 - 2.5e-33 115.4 19.3 1.4e-32 112.9 13.4 1.9 1 1 0 1 1 1 1 Major intrinsic protein LSM PF01423.17 AIN97855.1 - 9.8e-12 44.2 0.5 1.3e-11 43.8 0.3 1.2 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 AIN97855.1 - 0.00077 19.3 0.2 0.0012 18.7 0.1 1.3 1 0 0 1 1 1 1 Ataxin 2 SM domain DnaJ PF00226.26 AIN97856.1 - 4.4e-18 64.7 0.0 9.1e-18 63.7 0.0 1.6 1 0 0 1 1 1 1 DnaJ domain TPR_11 PF13414.1 AIN97856.1 - 1.5 8.5 8.3 0.38 10.4 0.1 3.5 3 0 0 3 3 3 0 TPR repeat Dynein_heavy PF03028.10 AIN97857.1 - 5.4e-215 715.6 0.0 5.4e-215 715.6 0.0 2.5 2 0 0 2 2 2 1 Dynein heavy chain and region D6 of dynein motor DHC_N1 PF08385.7 AIN97857.1 - 1.5e-131 439.6 0.8 1.5e-131 439.6 0.5 3.1 3 0 0 3 3 2 1 Dynein heavy chain, N-terminal region 1 DHC_N2 PF08393.8 AIN97857.1 - 3.4e-121 404.5 3.1 3.4e-121 404.5 2.2 5.1 5 0 0 5 5 5 1 Dynein heavy chain, N-terminal region 2 AAA_6 PF12774.2 AIN97857.1 - 5e-101 337.0 0.1 1.8e-100 335.2 0.0 2.1 2 0 0 2 2 2 1 Hydrolytic ATP binding site of dynein motor region D1 AAA_8 PF12780.2 AIN97857.1 - 7.4e-71 238.2 0.0 1.3e-70 237.4 0.0 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region D4 AAA_7 PF12775.2 AIN97857.1 - 4.1e-53 180.2 0.2 2e-52 177.9 0.0 2.3 2 1 0 2 2 2 1 P-loop containing dynein motor region D3 AAA_9 PF12781.2 AIN97857.1 - 4.5e-46 156.5 0.0 1e-45 155.3 0.0 1.7 1 0 0 1 1 1 1 ATP-binding dynein motor region D5 MT PF12777.2 AIN97857.1 - 1.1e-41 142.7 9.2 1.9e-41 141.9 6.3 1.4 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_5 PF07728.9 AIN97857.1 - 4.8e-22 78.1 3.3 6.3e-08 32.4 0.0 7.3 6 2 0 6 6 5 3 AAA domain (dynein-related subfamily) AAA PF00004.24 AIN97857.1 - 1.1e-07 32.1 6.3 0.7 10.0 0.0 6.7 7 0 0 7 7 5 2 ATPase family associated with various cellular activities (AAA) DUF258 PF03193.11 AIN97857.1 - 5.1e-05 22.5 2.0 0.025 13.7 0.2 3.6 3 0 0 3 3 3 1 Protein of unknown function, DUF258 AAA_33 PF13671.1 AIN97857.1 - 0.0002 21.2 4.3 0.14 12.0 0.0 5.2 5 0 0 5 5 5 1 AAA domain AAA_17 PF13207.1 AIN97857.1 - 0.00035 21.3 0.0 3.6 8.4 0.0 4.8 4 0 0 4 4 3 1 AAA domain AAA_22 PF13401.1 AIN97857.1 - 0.0034 17.5 6.9 2.1 8.5 0.0 5.8 7 0 0 7 7 5 1 AAA domain AAA_29 PF13555.1 AIN97857.1 - 0.04 13.4 0.6 0.72 9.4 0.0 2.7 2 0 0 2 2 2 0 P-loop containing region of AAA domain ABC_tran PF00005.22 AIN97857.1 - 0.075 13.3 7.5 1.1 9.5 0.1 4.4 5 0 0 5 5 4 0 ABC transporter RNA_helicase PF00910.17 AIN97857.1 - 0.078 13.1 2.4 4.1 7.6 0.0 3.3 3 0 0 3 3 3 0 RNA helicase MobB PF03205.9 AIN97857.1 - 0.25 11.0 4.8 1 9.0 0.5 3.1 3 0 0 3 3 2 0 Molybdopterin guanine dinucleotide synthesis protein B SMC_N PF02463.14 AIN97857.1 - 0.51 9.5 0.2 4.9 6.3 0.0 2.6 3 0 0 3 3 3 0 RecF/RecN/SMC N terminal domain AAA_18 PF13238.1 AIN97857.1 - 1 9.6 7.0 4.1 7.7 0.0 4.6 5 0 0 5 5 3 0 AAA domain HATPase_c PF02518.21 AIN97859.1 - 5.1e-13 48.7 0.0 9.9e-13 47.7 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase NMO PF03060.10 AIN97859.1 - 0.039 13.1 0.0 0.065 12.3 0.0 1.3 1 0 0 1 1 1 0 Nitronate monooxygenase Pet191_N PF10203.4 AIN97860.1 - 5.8e-17 61.4 3.8 7.8e-17 61.0 2.7 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein PET191 NIF PF03031.13 AIN97861.1 - 5.8e-29 100.8 0.0 8.9e-29 100.2 0.0 1.3 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase DUF705 PF05152.7 AIN97861.1 - 0.00011 21.3 0.0 0.00016 20.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF705) HAD_2 PF13419.1 AIN97861.1 - 0.024 14.8 0.3 0.3 11.3 0.0 2.6 2 2 0 2 2 2 0 Haloacid dehalogenase-like hydrolase PI3_PI4_kinase PF00454.22 AIN97863.1 - 2.6e-51 174.3 0.2 6.3e-51 173.1 0.2 1.7 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FAT PF02259.18 AIN97863.1 - 2.6e-24 85.8 0.1 8.7e-24 84.1 0.1 2.0 1 1 0 1 1 1 1 FAT domain Rapamycin_bind PF08771.6 AIN97863.1 - 1.5e-20 73.0 0.1 1.7e-19 69.7 0.1 3.0 2 0 0 2 2 2 1 Rapamycin binding domain FATC PF02260.15 AIN97863.1 - 2.3e-13 49.3 0.5 9.5e-13 47.3 0.0 2.4 2 0 0 2 2 2 1 FATC domain DUF3385 PF11865.3 AIN97863.1 - 2.4e-12 47.0 2.2 7.9e-12 45.3 0.2 2.9 2 0 0 2 2 2 1 Domain of unknown function (DUF3385) PDZ PF00595.19 AIN97863.1 - 0.00049 20.2 0.1 0.0012 18.9 0.1 1.6 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) DUF3279 PF11682.3 AIN97863.1 - 0.029 13.9 0.0 14 5.2 0.0 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3279) TPR_11 PF13414.1 AIN97863.1 - 0.044 13.4 0.0 0.18 11.4 0.0 2.0 1 0 0 1 1 1 0 TPR repeat PDZ_2 PF13180.1 AIN97863.1 - 0.065 13.1 0.0 0.17 11.8 0.0 1.6 1 0 0 1 1 1 0 PDZ domain Tmemb_cc2 PF10267.4 AIN97864.1 - 0.023 13.3 0.5 0.041 12.4 0.3 1.3 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein SHIPPO-rpt PF07004.7 AIN97864.1 - 0.082 13.8 0.8 0.25 12.2 0.5 1.8 1 0 0 1 1 1 0 Sperm-tail PG-rich repeat PIG-Y PF15159.1 AIN97865.1 - 4.5e-06 26.7 0.1 6.4e-06 26.2 0.1 1.2 1 0 0 1 1 1 1 Phosphatidylinositol N-acetylglucosaminyltransferase subunit Y LMBR1 PF04791.11 AIN97865.1 - 0.15 10.6 1.7 0.28 9.7 1.1 1.5 1 1 0 1 1 1 0 LMBR1-like membrane protein COMP PF11598.3 AIN97866.1 - 0.14 12.2 1.3 0.5 10.4 0.1 2.2 2 0 0 2 2 2 0 Cartilage oligomeric matrix protein HECT PF00632.20 AIN97867.1 - 1.5e-47 162.3 0.0 2.9e-47 161.3 0.0 1.4 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Adaptin_N PF01602.15 AIN97868.1 - 9e-72 242.0 5.1 1.2e-71 241.6 3.5 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptinC2 PF02883.15 AIN97868.1 - 5.2e-10 39.6 0.1 1e-09 38.7 0.0 1.5 1 0 0 1 1 1 1 Adaptin C-terminal domain Ribosomal_L7Ae PF01248.21 AIN97869.1 - 1.3e-18 66.2 0.4 1.6e-18 65.9 0.3 1.2 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Rgp1 PF08737.5 AIN97870.1 - 6.1e-07 28.8 0.1 0.0001 21.5 0.0 2.1 2 0 0 2 2 2 2 Rgp1 Arrestin_N PF00339.24 AIN97870.1 - 0.032 14.0 0.5 0.081 12.7 0.0 2.0 2 0 0 2 2 2 0 Arrestin (or S-antigen), N-terminal domain Peptidase_C78 PF07910.8 AIN97871.1 - 4.9e-50 169.6 0.0 6.8e-50 169.2 0.0 1.2 1 0 0 1 1 1 1 Peptidase family C78 UNC45-central PF11701.3 AIN97873.1 - 0.01 15.4 0.7 0.018 14.6 0.5 1.4 1 0 0 1 1 1 0 Myosin-binding striated muscle assembly central DUF445 PF04286.7 AIN97873.1 - 0.018 14.6 0.1 0.022 14.3 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF445) FANCI_S1-cap PF14674.1 AIN97873.1 - 0.095 12.7 0.4 2.2 8.4 0.1 2.4 2 0 0 2 2 2 0 FANCI solenoid 1 cap tRNA_synt_1c_R1 PF04558.10 AIN97873.1 - 0.15 11.5 1.6 5.3 6.5 0.2 2.7 1 1 2 3 3 3 0 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 Prenyltrans PF00432.16 AIN97874.1 - 2.9e-71 234.6 13.8 1.4e-14 53.2 0.2 6.0 6 0 0 6 6 6 5 Prenyltransferase and squalene oxidase repeat Prenyltrans_2 PF13249.1 AIN97874.1 - 4.2e-49 165.6 0.5 1.2e-17 64.3 0.0 3.4 1 1 3 4 4 4 4 Prenyltransferase-like Prenyltrans_1 PF13243.1 AIN97874.1 - 2.3e-15 56.5 0.1 1.2e-05 25.2 0.0 4.4 1 1 3 4 4 4 4 Prenyltransferase-like A2M_comp PF07678.9 AIN97874.1 - 0.083 12.1 0.1 20 4.2 0.0 3.8 3 1 1 5 5 5 0 A-macroglobulin complement component Phage_tail_L PF05100.7 AIN97876.1 - 0.076 12.1 0.0 0.23 10.5 0.0 1.7 2 0 0 2 2 2 0 Phage minor tail protein L DUF2003 PF09404.5 AIN97876.1 - 0.11 10.8 1.0 0.16 10.3 0.1 1.6 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF2003) TMF_TATA_bd PF12325.3 AIN97876.1 - 0.2 11.3 2.0 0.38 10.4 0.2 2.3 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding UCH PF00443.24 AIN97877.1 - 3e-37 128.2 0.1 5e-37 127.4 0.1 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 AIN97877.1 - 1.2e-16 61.0 0.0 2.3e-16 60.1 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DUF4361 PF14274.1 AIN97877.1 - 0.041 13.5 0.2 0.13 11.9 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4361) DnaJ PF00226.26 AIN97879.1 - 1.5e-07 31.0 0.0 4.5e-07 29.5 0.0 1.7 2 0 0 2 2 2 1 DnaJ domain Ribosomal_L19e PF01280.15 AIN97879.1 - 0.081 12.6 0.3 0.13 12.0 0.2 1.3 1 0 0 1 1 1 0 Ribosomal protein L19e GRIP PF01465.15 AIN97880.1 - 8.3e-13 47.6 0.3 7.6e-12 44.5 0.0 2.4 2 0 0 2 2 2 1 GRIP domain DUF1664 PF07889.7 AIN97880.1 - 0.39 10.5 6.0 1.5 8.6 2.6 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Reo_sigmaC PF04582.7 AIN97880.1 - 0.49 9.5 9.0 2.4 7.2 1.6 2.6 2 1 1 3 3 3 0 Reovirus sigma C capsid protein Acetyltransf_11 PF13720.1 AIN97880.1 - 0.62 10.3 3.0 41 4.5 0.6 3.3 2 0 0 2 2 2 0 Udp N-acetylglucosamine O-acyltransferase; Domain 2 Baculo_PEP_C PF04513.7 AIN97880.1 - 2.7 7.8 12.7 0.42 10.4 4.0 2.8 2 2 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus FliD_N PF02465.13 AIN97880.1 - 3.9 7.8 12.0 14 6.1 3.8 3.0 2 1 0 2 2 2 0 Flagellar hook-associated protein 2 N-terminus GAGA_bind PF06217.7 AIN97880.1 - 5.5 6.8 17.1 0.84 9.5 8.2 1.9 1 1 0 2 2 2 0 GAGA binding protein-like family Cauli_AT PF03233.8 AIN97880.1 - 6.2 6.5 8.2 9.2 5.9 3.1 2.7 2 1 1 3 3 3 0 Aphid transmission protein HALZ PF02183.13 AIN97880.1 - 7.2 6.4 13.7 0.39 10.4 2.7 3.9 4 0 0 4 4 4 0 Homeobox associated leucine zipper Peptidase_C50 PF03568.12 AIN97882.1 - 0.072 11.7 0.0 0.13 10.9 0.0 1.3 1 0 0 1 1 1 0 Peptidase family C50 Abhydrolase_6 PF12697.2 AIN97883.1 - 1e-09 38.6 0.1 1.4e-09 38.1 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 AIN97883.1 - 0.00057 19.5 0.0 0.0022 17.5 0.0 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 AIN97883.1 - 0.00066 19.4 0.0 0.00092 18.9 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF1620 PF07774.8 AIN97884.1 - 5.1e-49 166.4 0.0 9.6e-49 165.5 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1620) PQQ_2 PF13360.1 AIN97884.1 - 0.19 11.1 5.7 0.36 10.2 1.5 3.0 3 1 0 3 3 3 0 PQQ-like domain Rep-A_N PF04057.7 AIN97886.1 - 0.026 14.3 0.0 0.059 13.1 0.0 1.5 1 0 0 1 1 1 0 Replication factor-A protein 1, N-terminal domain DHC_N2 PF08393.8 AIN97887.1 - 9.4e-120 399.8 3.0 9.4e-120 399.8 2.1 4.8 4 0 0 4 4 4 1 Dynein heavy chain, N-terminal region 2 Dynein_heavy PF03028.10 AIN97887.1 - 2e-112 376.5 0.3 5.2e-112 375.1 0.0 1.8 2 0 0 2 2 1 1 Dynein heavy chain and region D6 of dynein motor AAA_6 PF12774.2 AIN97887.1 - 3.4e-82 275.4 0.0 2.4e-81 272.6 0.0 2.2 2 0 0 2 2 2 1 Hydrolytic ATP binding site of dynein motor region D1 DHC_N1 PF08385.7 AIN97887.1 - 2.6e-33 115.2 0.0 2.6e-33 115.2 0.0 3.7 3 0 0 3 3 3 1 Dynein heavy chain, N-terminal region 1 AAA_9 PF12781.2 AIN97887.1 - 7.9e-33 113.2 0.2 7.9e-33 113.2 0.1 1.9 2 0 0 2 2 2 1 ATP-binding dynein motor region D5 AAA_5 PF07728.9 AIN97887.1 - 2.1e-32 111.7 0.0 5.1e-21 74.8 0.0 5.6 4 1 0 4 4 4 3 AAA domain (dynein-related subfamily) AAA_8 PF12780.2 AIN97887.1 - 3.2e-28 98.4 0.5 1.5e-27 96.2 0.1 2.2 2 0 0 2 2 2 1 P-loop containing dynein motor region D4 MT PF12777.2 AIN97887.1 - 1.5e-26 92.9 12.7 4.2e-26 91.5 8.8 1.8 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_7 PF12775.2 AIN97887.1 - 3.7e-21 75.4 0.7 7.1e-20 71.2 0.1 2.6 2 0 0 2 2 2 1 P-loop containing dynein motor region D3 AAA_22 PF13401.1 AIN97887.1 - 9.2e-12 45.2 0.0 0.0024 18.0 0.0 5.0 3 0 0 3 3 3 3 AAA domain AAA_16 PF13191.1 AIN97887.1 - 1.2e-11 44.9 9.3 7.8e-05 22.7 0.0 6.6 7 0 0 7 7 7 3 AAA ATPase domain AAA PF00004.24 AIN97887.1 - 5.5e-11 42.7 0.0 0.065 13.4 0.0 4.4 3 0 0 3 3 3 3 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 AIN97887.1 - 3.7e-08 34.2 0.1 0.0018 19.1 0.0 5.4 4 0 0 4 4 4 1 AAA domain DUF258 PF03193.11 AIN97887.1 - 5.3e-07 28.9 0.0 0.0002 20.6 0.0 3.0 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_33 PF13671.1 AIN97887.1 - 5.4e-07 29.5 0.0 0.013 15.3 0.0 4.0 3 0 0 3 3 3 2 AAA domain RNA_helicase PF00910.17 AIN97887.1 - 1.5e-06 28.3 0.0 0.59 10.3 0.0 3.7 3 0 0 3 3 3 2 RNA helicase AAA_28 PF13521.1 AIN97887.1 - 1.5e-06 28.2 0.0 0.3 11.0 0.0 4.1 3 0 0 3 3 3 2 AAA domain AAA_14 PF13173.1 AIN97887.1 - 7.2e-06 25.9 0.0 0.15 11.9 0.0 4.3 4 0 0 4 4 3 1 AAA domain ABC_tran PF00005.22 AIN97887.1 - 1e-05 25.8 6.6 0.0044 17.3 0.0 4.8 5 0 0 5 5 3 2 ABC transporter AAA_19 PF13245.1 AIN97887.1 - 1.5e-05 24.6 0.1 0.033 13.9 0.0 4.2 4 0 0 4 4 3 1 Part of AAA domain NACHT PF05729.7 AIN97887.1 - 2.4e-05 24.0 0.6 0.18 11.4 0.0 3.3 3 0 0 3 3 2 2 NACHT domain Sigma54_activ_2 PF14532.1 AIN97887.1 - 4.1e-05 23.6 0.5 0.27 11.2 0.0 4.9 4 0 0 4 4 4 1 Sigma-54 interaction domain AAA_30 PF13604.1 AIN97887.1 - 4.6e-05 23.0 0.0 0.11 12.1 0.0 3.5 3 0 0 3 3 3 1 AAA domain AAA_18 PF13238.1 AIN97887.1 - 0.00011 22.5 3.6 0.019 15.2 0.0 5.5 5 0 0 5 5 5 1 AAA domain Guanylate_kin PF00625.16 AIN97887.1 - 0.00032 20.1 6.3 0.089 12.2 0.0 4.4 4 0 0 4 4 4 2 Guanylate kinase Zeta_toxin PF06414.7 AIN97887.1 - 0.00047 19.3 0.0 0.58 9.2 0.0 3.8 3 0 0 3 3 3 1 Zeta toxin AAA_10 PF12846.2 AIN97887.1 - 0.00052 19.5 0.3 0.19 11.1 0.1 3.1 2 0 0 2 2 2 1 AAA-like domain AAA_29 PF13555.1 AIN97887.1 - 0.00058 19.3 0.0 0.012 15.1 0.0 2.9 2 0 0 2 2 2 1 P-loop containing region of AAA domain cobW PF02492.14 AIN97887.1 - 0.00089 18.7 2.6 3.1 7.1 0.0 3.9 3 1 0 3 3 3 1 CobW/HypB/UreG, nucleotide-binding domain Arch_ATPase PF01637.13 AIN97887.1 - 0.00094 18.9 12.5 0.053 13.2 0.0 4.5 5 0 0 5 5 3 2 Archaeal ATPase Mg_chelatase PF01078.16 AIN97887.1 - 0.0014 17.8 0.1 2.7 7.0 0.0 3.3 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI AAA_24 PF13479.1 AIN97887.1 - 0.0023 17.5 0.0 11 5.5 0.0 3.5 3 0 0 3 3 3 0 AAA domain UPF0079 PF02367.12 AIN97887.1 - 0.0051 16.4 0.1 1.8 8.1 0.0 3.5 3 0 0 3 3 3 1 Uncharacterised P-loop hydrolase UPF0079 MobB PF03205.9 AIN97887.1 - 0.03 14.0 0.1 0.51 10.0 0.0 2.8 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_21 PF13304.1 AIN97887.1 - 0.034 14.1 0.0 0.083 12.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.18 AIN97887.1 - 0.053 13.4 0.2 7.7 6.5 0.0 3.1 2 0 0 2 2 2 0 50S ribosome-binding GTPase SMC_N PF02463.14 AIN97887.1 - 0.17 11.0 0.0 4.6 6.4 0.0 2.9 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 AIN97887.1 - 1.4 9.1 0.0 1.4 9.1 0.0 7.1 8 0 0 8 8 6 0 AAA domain zf-CCHC_3 PF13917.1 AIN97888.1 - 2e-15 56.2 2.3 2e-15 56.2 1.6 1.8 2 0 0 2 2 2 1 Zinc knuckle eIF3g PF12353.3 AIN97888.1 - 0.00059 19.7 1.0 0.00059 19.7 0.7 1.9 2 0 0 2 2 2 1 Eukaryotic translation initiation factor 3 subunit G DUF1193 PF06702.7 AIN97889.1 - 4.2e-06 26.3 0.0 1.1e-05 25.0 0.0 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF1193) Metallophos PF00149.23 AIN97890.1 - 1.3e-35 122.6 0.0 1.6e-35 122.3 0.0 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Complex1_LYR PF05347.10 AIN97893.1 - 0.079 12.7 0.5 0.18 11.6 0.4 1.6 1 0 0 1 1 1 0 Complex 1 protein (LYR family) Robl_LC7 PF03259.12 AIN97894.1 - 0.005 16.3 0.0 0.0068 15.9 0.0 1.4 1 1 0 1 1 1 1 Roadblock/LC7 domain FHA PF00498.21 AIN97895.1 - 1.2e-07 31.7 0.0 2.3e-07 30.7 0.0 1.5 1 0 0 1 1 1 1 FHA domain BRCT PF00533.21 AIN97895.1 - 2e-07 31.0 0.0 1.4e-05 25.1 0.0 2.9 3 0 0 3 3 3 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.2 AIN97895.1 - 0.00013 21.7 0.0 0.00025 20.8 0.0 1.5 1 0 0 1 1 1 1 twin BRCT domain PDH PF02153.12 AIN97895.1 - 0.019 13.8 0.2 0.032 13.1 0.1 1.3 1 0 0 1 1 1 0 Prephenate dehydrogenase Kinesin PF00225.18 AIN97897.1 - 1.3e-104 349.5 0.3 1.3e-104 349.5 0.2 1.6 2 0 0 2 2 2 1 Kinesin motor domain Pex24p PF06398.6 AIN97897.1 - 5e-08 32.1 0.2 1.2e-07 30.8 0.1 1.6 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin SPX PF03105.14 AIN97897.1 - 0.042 13.6 8.7 0.068 12.9 6.0 1.3 1 0 0 1 1 1 0 SPX domain Cullin_binding PF03556.10 AIN97898.1 - 3.1e-14 53.0 0.6 5.6e-14 52.2 0.4 1.3 1 0 0 1 1 1 1 Cullin binding DUF2294 PF10057.4 AIN97898.1 - 0.15 11.6 0.0 0.26 10.9 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2294) Gar1 PF04410.9 AIN97899.1 - 8.5e-38 129.2 0.1 8.5e-38 129.2 0.1 2.0 2 0 0 2 2 2 1 Gar1/Naf1 RNA binding region zf-DHHC PF01529.15 AIN97900.1 - 2.5e-15 56.3 5.6 3.4e-15 55.8 2.8 1.9 1 1 1 2 2 2 1 DHHC palmitoyltransferase DUF307 PF03733.8 AIN97900.1 - 0.51 10.8 0.1 0.51 10.8 0.1 3.2 4 0 0 4 4 4 0 Domain of unknown function (DUF307) Virul_fac_BrkB PF03631.10 AIN97900.1 - 1.1 8.5 9.4 0.77 9.0 0.9 2.3 2 0 0 2 2 2 0 Virulence factor BrkB BIR PF00653.16 AIN97900.1 - 1.2 9.6 6.3 5.9 7.3 1.8 2.8 3 0 0 3 3 3 0 Inhibitor of Apoptosis domain Prominin PF05478.6 AIN97900.1 - 2.1 5.7 5.6 17 2.7 4.1 1.9 2 0 0 2 2 2 0 Prominin Coatomer_WDAD PF04053.9 AIN97901.1 - 8.5e-95 318.1 0.0 1.3e-94 317.5 0.0 1.2 1 0 0 1 1 1 1 Coatomer WD associated region COPI_C PF06957.6 AIN97901.1 - 1.5e-83 280.7 0.0 2.2e-83 280.1 0.0 1.1 1 0 0 1 1 1 1 Coatomer (COPI) alpha subunit C-terminus WD40 PF00400.27 AIN97901.1 - 1.6e-48 160.9 22.4 1e-10 41.0 0.1 7.1 7 0 0 7 7 7 6 WD domain, G-beta repeat TPR_2 PF07719.12 AIN97901.1 - 0.024 14.5 0.3 6.1 7.0 0.0 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_16 PF13432.1 AIN97901.1 - 0.063 13.9 5.0 4.9 7.9 0.3 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat ESSS PF10183.4 AIN97902.1 - 1.2e-13 51.3 5.6 1.4e-13 51.1 3.9 1.1 1 0 0 1 1 1 1 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) Proteasome PF00227.21 AIN97903.1 - 4.4e-30 104.3 0.0 5e-30 104.1 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit ESSS PF10183.4 AIN97904.1 - 1.2e-13 51.3 5.6 1.4e-13 51.1 3.9 1.1 1 0 0 1 1 1 1 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) adh_short PF00106.20 AIN97905.1 - 7.2e-08 32.5 6.0 3.3e-07 30.3 4.1 1.9 1 1 0 1 1 1 1 short chain dehydrogenase Epimerase PF01370.16 AIN97905.1 - 0.00073 19.0 0.0 0.0013 18.2 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PI3_PI4_kinase PF00454.22 AIN97906.1 - 1.4e-51 175.2 1.3 2.2e-51 174.5 0.3 1.9 2 0 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase FAT PF02259.18 AIN97906.1 - 5e-40 137.5 0.7 4.8e-39 134.3 0.5 2.4 1 1 0 1 1 1 1 FAT domain Rapamycin_bind PF08771.6 AIN97906.1 - 1.4e-32 111.7 1.4 3.5e-32 110.4 0.4 2.3 2 0 0 2 2 2 1 Rapamycin binding domain DUF3385 PF11865.3 AIN97906.1 - 2.9e-26 92.3 0.2 2.9e-25 89.0 0.0 3.0 3 0 0 3 3 3 1 Domain of unknown function (DUF3385) FATC PF02260.15 AIN97906.1 - 9.9e-12 44.0 0.2 3.6e-11 42.3 0.2 2.1 1 0 0 1 1 1 1 FATC domain HEAT PF02985.17 AIN97906.1 - 7.9e-06 25.5 2.6 2.3 8.4 0.0 6.6 5 0 0 5 5 5 1 HEAT repeat ADIP PF11559.3 AIN97907.1 - 0.00034 20.5 6.0 0.00039 20.3 4.2 1.1 1 0 0 1 1 1 1 Afadin- and alpha -actinin-Binding Tom22 PF04281.8 AIN97907.1 - 0.00038 19.9 1.9 0.00046 19.7 1.3 1.1 1 0 0 1 1 1 1 Mitochondrial import receptor subunit Tom22 IncA PF04156.9 AIN97907.1 - 0.00043 19.9 8.4 0.00052 19.6 5.8 1.1 1 0 0 1 1 1 1 IncA protein Rho_Binding PF08912.6 AIN97907.1 - 0.0026 18.0 4.0 0.0068 16.6 0.3 2.5 1 1 2 3 3 3 1 Rho Binding IFT57 PF10498.4 AIN97907.1 - 0.0053 15.5 4.0 0.0058 15.4 2.7 1.1 1 0 0 1 1 1 1 Intra-flagellar transport protein 57 GAS PF13851.1 AIN97907.1 - 0.0065 15.6 7.2 0.0075 15.4 5.0 1.0 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding USP8_interact PF08941.5 AIN97907.1 - 0.0072 15.6 0.7 0.0077 15.5 0.5 1.2 1 0 0 1 1 1 1 USP8 interacting Occludin_ELL PF07303.8 AIN97907.1 - 0.0075 16.9 1.8 0.0091 16.7 1.2 1.2 1 0 0 1 1 1 1 Occludin homology domain YkyA PF10368.4 AIN97907.1 - 0.0092 15.3 5.6 0.011 15.0 3.9 1.1 1 0 0 1 1 1 1 Putative cell-wall binding lipoprotein CorA PF01544.13 AIN97907.1 - 0.012 14.6 2.5 0.013 14.5 1.8 1.1 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein DUF4061 PF13270.1 AIN97907.1 - 0.017 15.1 3.2 0.1 12.7 0.2 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4061) T4SS PF07996.6 AIN97907.1 - 0.023 14.5 0.8 0.027 14.3 0.6 1.1 1 0 0 1 1 1 0 Type IV secretion system proteins PilJ PF13675.1 AIN97907.1 - 0.024 14.9 2.3 0.11 12.8 0.8 1.9 1 1 1 2 2 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term EIF_2_alpha PF07541.7 AIN97907.1 - 0.026 14.2 1.3 0.53 10.0 0.1 2.0 1 1 1 2 2 2 0 Eukaryotic translation initiation factor 2 alpha subunit DUF3450 PF11932.3 AIN97907.1 - 0.034 13.4 4.6 0.037 13.2 3.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) Lectin_N PF03954.9 AIN97907.1 - 0.035 13.5 1.8 0.25 10.7 0.1 2.0 1 1 1 2 2 2 0 Hepatic lectin, N-terminal domain FUSC PF04632.7 AIN97907.1 - 0.035 12.5 2.4 0.039 12.3 1.7 1.0 1 0 0 1 1 1 0 Fusaric acid resistance protein family Apt1 PF10351.4 AIN97907.1 - 0.036 12.9 3.3 0.042 12.7 2.3 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain RTBV_P46 PF06216.6 AIN97907.1 - 0.038 12.8 0.5 0.038 12.8 0.3 1.1 1 0 0 1 1 1 0 Rice tungro bacilliform virus P46 protein CCDC144C PF14915.1 AIN97907.1 - 0.046 12.6 8.0 0.061 12.2 5.5 1.2 1 0 0 1 1 1 0 CCDC144C protein coiled-coil region ERM PF00769.14 AIN97907.1 - 0.049 13.1 8.8 0.058 12.9 6.1 1.1 1 0 0 1 1 1 0 Ezrin/radixin/moesin family V_ATPase_I PF01496.14 AIN97907.1 - 0.057 11.2 2.9 0.064 11.1 2.0 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF3584 PF12128.3 AIN97907.1 - 0.057 10.7 5.7 0.058 10.7 3.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) M_domain PF12938.2 AIN97907.1 - 0.077 12.7 0.1 0.082 12.7 0.1 1.2 1 0 0 1 1 1 0 M domain of GW182 Lebercilin PF15619.1 AIN97907.1 - 0.08 12.3 8.4 0.19 11.0 5.8 1.6 1 1 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease AAA_13 PF13166.1 AIN97907.1 - 0.089 11.2 3.2 0.12 10.8 2.2 1.3 1 0 0 1 1 1 0 AAA domain Sec20 PF03908.8 AIN97907.1 - 0.11 12.2 2.0 0.28 10.9 0.4 2.0 1 1 1 2 2 2 0 Sec20 TPR_MLP1_2 PF07926.7 AIN97907.1 - 0.11 12.2 9.9 1.1 9.0 0.8 2.2 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein Filament PF00038.16 AIN97907.1 - 0.13 11.7 8.1 0.31 10.4 5.4 1.6 1 1 1 2 2 2 0 Intermediate filament protein Baculo_PEP_C PF04513.7 AIN97907.1 - 0.14 12.0 0.5 0.23 11.2 0.3 1.6 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Reo_sigmaC PF04582.7 AIN97907.1 - 0.15 11.2 2.8 0.16 11.1 1.9 1.1 1 0 0 1 1 1 0 Reovirus sigma C capsid protein DUF2422 PF10337.4 AIN97907.1 - 0.16 10.7 2.4 0.18 10.5 1.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2422) DivIVA PF05103.8 AIN97907.1 - 0.19 11.7 7.3 2.1 8.4 5.1 2.4 1 1 0 1 1 1 0 DivIVA protein Atg14 PF10186.4 AIN97907.1 - 0.21 10.4 5.8 0.24 10.3 4.0 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Med9 PF07544.8 AIN97907.1 - 0.24 11.1 0.2 0.24 11.1 0.1 2.6 1 1 2 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 CENP-F_leu_zip PF10473.4 AIN97907.1 - 0.25 11.2 9.4 0.36 10.6 6.5 1.3 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 APG6 PF04111.7 AIN97907.1 - 0.27 10.2 6.0 0.3 10.0 4.2 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 TBPIP PF07106.8 AIN97907.1 - 0.27 10.7 5.5 0.31 10.5 3.8 1.1 1 0 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Cluap1 PF10234.4 AIN97907.1 - 0.31 10.1 8.3 0.96 8.5 5.8 1.7 1 1 0 1 1 1 0 Clusterin-associated protein-1 Spectrin PF00435.16 AIN97907.1 - 0.32 11.2 4.8 2.3 8.5 1.4 2.1 1 1 1 2 2 2 0 Spectrin repeat Prefoldin_2 PF01920.15 AIN97907.1 - 0.33 10.7 9.0 0.14 11.9 2.8 2.2 1 1 1 2 2 2 0 Prefoldin subunit FliD_N PF02465.13 AIN97907.1 - 0.38 11.1 5.5 1.4 9.2 3.8 1.8 1 1 0 1 1 1 0 Flagellar hook-associated protein 2 N-terminus Uds1 PF15456.1 AIN97907.1 - 0.48 10.4 7.6 0.14 12.1 3.0 1.6 1 1 1 2 2 2 0 Up-regulated During Septation DivIC PF04977.10 AIN97907.1 - 0.53 9.8 10.1 1.6 8.2 0.2 2.8 1 1 2 3 3 3 0 Septum formation initiator DUF4164 PF13747.1 AIN97907.1 - 0.53 10.4 8.6 0.36 11.0 2.7 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4164) DUF2458 PF10454.4 AIN97907.1 - 0.58 10.0 4.4 1 9.2 0.4 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2458) DUF342 PF03961.8 AIN97907.1 - 0.7 8.2 4.7 1.1 7.5 3.3 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF342) DUF972 PF06156.8 AIN97907.1 - 0.74 10.1 3.8 1.9 8.8 2.6 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF972) COG2 PF06148.6 AIN97907.1 - 0.8 9.5 7.1 3 7.7 0.5 2.1 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 PspB PF06667.7 AIN97907.1 - 0.93 9.4 5.4 11 5.9 3.7 2.6 1 1 0 1 1 1 0 Phage shock protein B Med4 PF10018.4 AIN97907.1 - 0.93 8.8 5.8 2.4 7.5 4.1 1.7 1 1 0 1 1 1 0 Vitamin-D-receptor interacting Mediator subunit 4 CENP-Q PF13094.1 AIN97907.1 - 1.1 9.2 9.4 1.9 8.5 6.5 1.5 1 1 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit DUF724 PF05266.9 AIN97907.1 - 1.3 8.5 7.2 2.6 7.6 5.0 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF724) GrpE PF01025.14 AIN97907.1 - 1.8 8.0 7.6 2.5 7.6 5.3 1.3 1 1 0 1 1 1 0 GrpE Seryl_tRNA_N PF02403.17 AIN97907.1 - 2 8.4 8.2 0.53 10.3 2.6 1.9 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain DUF4140 PF13600.1 AIN97907.1 - 4.9 7.6 10.1 9.9 6.6 4.5 2.6 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) Rcd1 PF04078.8 AIN97908.1 - 1.6e-106 355.0 0.4 1.8e-106 354.7 0.3 1.0 1 0 0 1 1 1 1 Cell differentiation family, Rcd1-like HNF-1B_C PF04812.8 AIN97908.1 - 0.66 9.1 7.5 0.53 9.5 0.1 2.1 2 0 0 2 2 2 0 Hepatocyte nuclear factor 1 (HNF-1), beta isoform C terminus RRM_1 PF00076.17 AIN97909.1 - 3.9e-30 103.2 0.0 1.5e-14 53.3 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 AIN97909.1 - 4.2e-25 87.4 0.0 4.6e-14 52.1 0.0 3.1 3 0 0 3 3 3 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 AIN97909.1 - 2.8e-09 36.6 0.0 0.0024 17.6 0.0 3.9 3 2 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 AIN97909.1 - 0.0074 16.1 0.0 6.6 6.6 0.0 3.2 3 0 0 3 3 3 1 RNA binding motif Nup35_RRM_2 PF14605.1 AIN97909.1 - 0.0089 15.7 0.0 0.41 10.4 0.0 2.7 3 0 0 3 3 3 1 Nup53/35/40-type RNA recognition motif RNA_bind PF08675.6 AIN97909.1 - 0.02 14.8 0.1 2 8.4 0.0 2.6 2 1 0 2 2 2 0 RNA binding domain Limkain-b1 PF11608.3 AIN97909.1 - 0.13 11.9 0.1 8.8 6.1 0.0 2.4 2 0 0 2 2 2 0 Limkain b1 FAM176 PF14851.1 AIN97910.1 - 0.0082 15.8 1.5 0.014 15.1 1.0 1.3 1 0 0 1 1 1 1 FAM176 family Alg6_Alg8 PF03155.10 AIN97910.1 - 0.0092 14.8 2.6 0.011 14.6 1.8 1.0 1 0 0 1 1 1 1 ALG6, ALG8 glycosyltransferase family DUF308 PF03729.8 AIN97910.1 - 0.12 12.3 9.1 2.3 8.2 3.9 2.4 1 1 1 2 2 2 0 Short repeat of unknown function (DUF308) FixQ PF05545.6 AIN97910.1 - 3.4 7.3 4.9 6.1 6.5 0.9 2.7 2 1 0 2 2 2 0 Cbb3-type cytochrome oxidase component FixQ DUF3040 PF11239.3 AIN97910.1 - 4 7.5 6.4 5.5 7.1 1.3 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3040) WD40 PF00400.27 AIN97911.1 - 7.6e-08 31.9 7.4 0.0067 16.2 0.0 5.2 5 0 0 5 5 5 3 WD domain, G-beta repeat ARD PF03079.9 AIN97913.1 - 9.5e-27 93.8 0.0 9.5e-27 93.8 0.0 2.1 2 0 0 2 2 2 1 ARD/ARD' family Cupin_2 PF07883.6 AIN97913.1 - 4.3e-07 29.3 0.0 1.6e-06 27.5 0.0 1.8 2 0 0 2 2 2 1 Cupin domain AraC_binding PF02311.14 AIN97913.1 - 0.00015 21.4 0.0 0.00028 20.5 0.0 1.4 1 0 0 1 1 1 1 AraC-like ligand binding domain Cupin_3 PF05899.7 AIN97913.1 - 0.00038 19.7 0.0 0.00088 18.6 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF861) Cupin_6 PF12852.2 AIN97913.1 - 0.00074 19.1 0.0 0.0011 18.5 0.0 1.3 1 0 0 1 1 1 1 Cupin Cupin_8 PF13621.1 AIN97913.1 - 0.0092 15.5 1.4 0.018 14.5 0.0 2.0 2 1 0 2 2 2 1 Cupin-like domain Cupin_1 PF00190.17 AIN97913.1 - 0.015 14.7 0.0 0.03 13.7 0.0 1.4 1 0 0 1 1 1 0 Cupin Ehbp PF10622.4 AIN97913.1 - 0.13 12.2 0.1 0.78 9.7 0.0 2.2 2 0 0 2 2 2 0 Energy-converting hydrogenase B subunit P (EhbP) MAP7 PF05672.6 AIN97913.1 - 7.9 5.8 34.5 16 4.8 23.9 1.4 1 0 0 1 1 1 0 MAP7 (E-MAP-115) family cNMP_binding PF00027.24 AIN97915.1 - 9.2e-10 38.2 0.1 1.1e-08 34.7 0.0 2.7 3 0 0 3 3 3 1 Cyclic nucleotide-binding domain RNA_pol_Rpb2_6 PF00562.23 AIN97916.1 - 2.9e-114 381.8 0.0 4.2e-114 381.2 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.10 AIN97916.1 - 1.1e-44 151.8 1.2 1.6e-44 151.3 0.8 1.2 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_7 PF04560.15 AIN97916.1 - 5.2e-28 97.1 0.1 1.3e-27 95.8 0.1 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_2 PF04561.9 AIN97916.1 - 7.1e-21 74.4 0.1 1.5e-20 73.4 0.1 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_3 PF04565.11 AIN97916.1 - 6.6e-19 67.4 0.0 1.3e-18 66.5 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_4 PF04566.8 AIN97916.1 - 7.6e-19 67.2 1.5 7.6e-19 67.2 1.0 2.2 3 0 0 3 3 3 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_5 PF04567.12 AIN97916.1 - 1.2e-10 41.1 0.2 3.1e-10 39.8 0.1 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 WD40 PF00400.27 AIN97917.1 - 2.6e-20 71.4 12.4 4.3e-09 35.8 0.6 4.4 4 0 0 4 4 4 3 WD domain, G-beta repeat Nup160 PF11715.3 AIN97917.1 - 0.029 12.5 1.6 0.087 10.9 1.1 1.9 1 1 0 1 1 1 0 Nucleoporin Nup120/160 Hira PF07569.6 AIN97917.1 - 0.046 12.9 1.4 6.9 5.8 0.1 3.1 2 1 2 4 4 4 0 TUP1-like enhancer of split DOT1 PF08123.8 AIN97918.1 - 1.9e-19 69.7 0.0 2.9e-19 69.2 0.0 1.1 1 0 0 1 1 1 1 Histone methylation protein DOT1 Methyltransf_18 PF12847.2 AIN97918.1 - 4.4e-07 30.4 0.0 8e-07 29.6 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 AIN97918.1 - 1.9e-06 27.8 0.0 2.9e-06 27.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 AIN97918.1 - 1.2e-05 25.5 0.0 2.6e-05 24.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 AIN97918.1 - 2.5e-05 23.9 0.0 3.6e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 AIN97918.1 - 0.00014 22.2 0.0 0.00046 20.6 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 AIN97918.1 - 0.0046 16.6 0.0 0.0057 16.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 AIN97918.1 - 0.02 15.3 0.0 0.035 14.5 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_32 PF13679.1 AIN97918.1 - 0.027 14.1 0.0 0.073 12.7 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase domain AdoMet_MTase PF07757.8 AIN97918.1 - 0.067 13.3 0.0 0.13 12.4 0.0 1.5 1 0 0 1 1 1 0 Predicted AdoMet-dependent methyltransferase CMAS PF02353.15 AIN97918.1 - 0.079 12.0 0.0 0.12 11.4 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase PHO4 PF01384.15 AIN97919.1 - 9.1e-106 353.1 17.6 1.2e-105 352.7 12.2 1.2 1 0 0 1 1 1 1 Phosphate transporter family ASF1_hist_chap PF04729.8 AIN97921.1 - 2.8e-52 176.4 0.0 3.1e-52 176.3 0.0 1.0 1 0 0 1 1 1 1 ASF1 like histone chaperone BRCA-2_OB1 PF09103.5 AIN97922.1 - 8.9e-33 112.4 0.0 1.5e-32 111.8 0.0 1.3 1 0 0 1 1 1 1 BRCA2, oligonucleotide/oligosaccharide-binding, domain 1 BRCA2 PF00634.13 AIN97922.1 - 1.2e-05 24.4 0.2 0.00011 21.3 0.1 2.2 2 0 0 2 2 2 1 BRCA2 repeat BK_channel_a PF03493.13 AIN97925.1 - 1.3e-20 73.2 0.0 3.7e-20 71.7 0.0 1.9 1 0 0 1 1 1 1 Calcium-activated BK potassium channel alpha subunit Ion_trans_2 PF07885.11 AIN97925.1 - 5.4e-12 45.2 6.4 5.4e-12 45.2 4.5 2.6 2 1 0 2 2 2 1 Ion channel PGK PF00162.14 AIN97926.1 - 7.5e-153 508.6 0.0 8.7e-153 508.4 0.0 1.0 1 0 0 1 1 1 1 Phosphoglycerate kinase NB-ARC PF00931.17 AIN97927.1 - 5.4e-07 28.7 0.1 0.0046 15.8 0.0 2.2 1 1 1 2 2 2 2 NB-ARC domain AAA_16 PF13191.1 AIN97927.1 - 0.00015 21.8 0.1 0.00048 20.1 0.0 1.9 2 0 0 2 2 2 1 AAA ATPase domain AAA_14 PF13173.1 AIN97927.1 - 0.0034 17.2 0.0 0.011 15.5 0.0 1.8 2 0 0 2 2 2 1 AAA domain DUF258 PF03193.11 AIN97927.1 - 0.083 12.0 0.0 0.15 11.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 NACHT PF05729.7 AIN97927.1 - 0.088 12.4 0.1 0.78 9.3 0.0 2.1 1 1 1 2 2 2 0 NACHT domain Mg_chelatase PF01078.16 AIN97927.1 - 0.11 11.6 0.0 3.2 6.8 0.0 2.3 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI Arch_ATPase PF01637.13 AIN97927.1 - 0.15 11.7 0.0 20 4.7 0.0 2.1 1 1 1 2 2 2 0 Archaeal ATPase MORN PF02493.15 AIN97928.1 - 3.8e-12 45.1 13.4 1.6e-06 27.4 0.0 7.0 7 0 0 7 7 7 4 MORN repeat SM-ATX PF14438.1 AIN97928.1 - 0.11 12.3 0.7 11 6.0 0.0 3.7 4 0 0 4 4 4 0 Ataxin 2 SM domain DUF1736 PF08409.6 AIN97930.1 - 9.8e-25 85.9 0.3 2.8e-24 84.4 0.2 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1736) TPR_11 PF13414.1 AIN97930.1 - 0.092 12.3 0.3 2.3 7.9 0.0 2.6 1 1 1 2 2 2 0 TPR repeat TraL PF07178.6 AIN97930.1 - 7.1 6.7 10.3 0.89 9.6 0.0 4.1 5 1 1 6 6 6 0 TraL protein O-antigen_lig PF13425.1 AIN97930.1 - 9.1 6.2 18.6 19 5.2 0.7 3.1 2 1 0 2 2 2 0 O-antigen ligase like membrane protein Sec20 PF03908.8 AIN97931.1 - 0.088 12.5 5.2 0.17 11.5 2.8 2.2 1 1 1 2 2 2 0 Sec20 Cep57_CLD PF14073.1 AIN97931.1 - 0.67 9.7 15.2 0.54 10.0 5.9 2.3 1 1 1 2 2 2 0 Centrosome localisation domain of Cep57 Mto2_bdg PF12808.2 AIN97931.1 - 1.5 8.9 6.1 0.52 10.4 0.3 2.8 3 0 0 3 3 3 0 Micro-tubular organiser Mto1 C-term Mto2-binding region Atg14 PF10186.4 AIN97931.1 - 3.2 6.6 13.5 6.2 5.6 0.4 2.1 1 1 1 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 ERM PF00769.14 AIN97931.1 - 3.6 7.0 15.7 1.1 8.7 8.6 1.8 2 1 0 2 2 2 0 Ezrin/radixin/moesin family TPR_MLP1_2 PF07926.7 AIN97931.1 - 4.7 6.9 16.5 4.8e+02 0.4 11.4 2.7 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein LRR_6 PF13516.1 AIN97932.1 - 0.04 13.9 0.0 8.5 6.7 0.0 3.1 3 0 0 3 3 3 0 Leucine Rich repeat Kelch_3 PF13415.1 AIN97936.1 - 1.6e-27 94.9 11.3 3.1e-06 27.1 0.0 6.9 8 0 0 8 8 8 5 Galactose oxidase, central domain Kelch_6 PF13964.1 AIN97936.1 - 8.4e-24 82.7 6.9 5.7e-06 26.2 0.0 5.8 5 1 1 6 6 6 5 Kelch motif Kelch_5 PF13854.1 AIN97936.1 - 7.8e-20 70.4 12.9 4e-07 29.8 0.0 5.2 5 0 0 5 5 5 4 Kelch motif Kelch_1 PF01344.20 AIN97936.1 - 9.4e-20 69.8 10.7 1.8e-05 24.1 0.1 6.0 6 1 0 6 6 6 5 Kelch motif Kelch_4 PF13418.1 AIN97936.1 - 1e-18 66.7 6.2 3.2e-06 26.7 0.0 5.8 5 1 0 5 5 5 4 Galactose oxidase, central domain Kelch_2 PF07646.10 AIN97936.1 - 3.8e-14 51.7 17.3 0.00074 19.1 0.1 6.7 6 1 0 6 6 6 5 Kelch motif DUF4516 PF14990.1 AIN97938.1 - 0.027 14.0 0.0 0.043 13.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4516) DS PF01916.12 AIN97940.1 - 1.2e-74 251.1 0.0 1.6e-74 250.7 0.0 1.0 1 0 0 1 1 1 1 Deoxyhypusine synthase AAA_5 PF07728.9 AIN97941.1 - 6.2e-123 405.0 0.0 3e-22 78.8 0.0 9.0 6 2 2 8 8 8 8 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 AIN97941.1 - 8.5e-25 86.8 0.0 0.0061 16.1 0.0 8.4 8 0 0 8 8 8 4 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 AIN97941.1 - 1.4e-22 80.2 0.2 0.014 15.5 0.0 7.6 7 0 0 7 7 7 5 AAA domain AAA PF00004.24 AIN97941.1 - 4.1e-20 72.3 3.3 0.00075 19.6 0.0 7.3 6 1 0 6 6 6 4 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 AIN97941.1 - 3.9e-19 69.3 17.4 0.0008 19.4 0.0 9.6 9 1 0 9 9 8 4 AAA ATPase domain AAA_14 PF13173.1 AIN97941.1 - 1.7e-16 60.2 0.0 0.00084 19.2 0.0 6.4 5 1 0 5 5 5 3 AAA domain Sigma54_activ_2 PF14532.1 AIN97941.1 - 2.1e-16 60.2 0.2 0.00032 20.7 0.0 6.8 6 0 0 6 6 6 3 Sigma-54 interaction domain Sigma54_activat PF00158.21 AIN97941.1 - 9.3e-16 57.7 0.1 0.021 14.2 0.0 6.5 6 0 0 6 6 6 3 Sigma-54 interaction domain AAA_17 PF13207.1 AIN97941.1 - 7.5e-15 55.8 0.7 0.086 13.6 0.0 7.1 7 0 0 7 7 5 3 AAA domain AAA_33 PF13671.1 AIN97941.1 - 7.7e-11 42.0 2.0 0.44 10.4 0.0 6.8 7 0 0 7 7 6 3 AAA domain T2SE PF00437.15 AIN97941.1 - 3.1e-10 39.4 1.5 0.079 11.8 0.0 6.2 6 0 0 6 6 6 2 Type II/IV secretion system protein AAA_29 PF13555.1 AIN97941.1 - 3.1e-10 39.4 1.5 2.3 7.7 0.0 6.8 6 0 0 6 6 6 1 P-loop containing region of AAA domain AAA_18 PF13238.1 AIN97941.1 - 6.4e-10 39.4 2.7 0.11 12.7 0.0 7.0 6 0 0 6 6 6 2 AAA domain IstB_IS21 PF01695.12 AIN97941.1 - 3.4e-09 36.3 0.3 0.12 11.8 0.0 4.5 5 0 0 5 5 3 3 IstB-like ATP binding protein UPF0079 PF02367.12 AIN97941.1 - 5.6e-09 35.6 5.5 0.036 13.7 0.0 6.3 6 0 0 6 6 6 1 Uncharacterised P-loop hydrolase UPF0079 AAA_25 PF13481.1 AIN97941.1 - 8.2e-09 35.1 1.1 0.29 10.5 0.0 6.0 5 0 0 5 5 5 1 AAA domain AAA_19 PF13245.1 AIN97941.1 - 2.2e-08 33.7 10.5 1.9 8.3 0.0 7.0 7 0 0 7 7 5 2 Part of AAA domain DUF258 PF03193.11 AIN97941.1 - 2.5e-08 33.2 1.0 0.85 8.7 0.0 5.3 5 0 0 5 5 5 2 Protein of unknown function, DUF258 DUF815 PF05673.8 AIN97941.1 - 1.3e-07 30.7 3.1 0.14 11.1 0.0 5.0 6 0 0 6 6 5 2 Protein of unknown function (DUF815) RNA_helicase PF00910.17 AIN97941.1 - 3.4e-07 30.4 1.9 0.27 11.4 0.0 6.1 6 0 0 6 6 6 1 RNA helicase ABC_tran PF00005.22 AIN97941.1 - 4.7e-06 26.9 24.5 0.24 11.7 0.0 7.2 8 0 0 8 8 6 2 ABC transporter RuvB_N PF05496.7 AIN97941.1 - 0.00027 20.0 0.3 3 6.8 0.0 4.9 6 0 0 6 6 6 1 Holliday junction DNA helicase ruvB N-terminus NACHT PF05729.7 AIN97941.1 - 0.00057 19.5 7.5 0.72 9.4 0.0 5.6 6 0 0 6 6 6 1 NACHT domain Miro PF08477.8 AIN97941.1 - 0.0039 17.6 1.4 42 4.6 0.0 4.8 4 0 0 4 4 4 0 Miro-like protein KaiC PF06745.8 AIN97941.1 - 0.0056 15.8 0.3 18 4.3 0.0 4.7 5 0 0 5 5 5 0 KaiC ArgK PF03308.11 AIN97941.1 - 0.011 14.5 1.7 2.1 7.0 0.1 3.7 4 0 0 4 4 4 0 ArgK protein Rad17 PF03215.10 AIN97941.1 - 0.012 14.3 2.8 30 3.0 0.0 4.9 6 0 0 6 6 6 0 Rad17 cell cycle checkpoint protein AAA_6 PF12774.2 AIN97941.1 - 0.041 13.4 0.0 7.5 6.0 0.0 3.9 4 0 0 4 4 4 0 Hydrolytic ATP binding site of dynein motor region D1 TIP49 PF06068.8 AIN97941.1 - 0.048 12.3 0.2 3.6 6.2 0.1 3.3 3 0 0 3 3 3 0 TIP49 C-terminus NTPase_1 PF03266.10 AIN97941.1 - 0.091 12.4 4.8 4.7 6.8 0.0 4.0 5 0 0 5 5 4 0 NTPase DNA_pol3_delta2 PF13177.1 AIN97941.1 - 0.1 12.2 0.3 11 5.6 0.0 3.8 4 0 0 4 4 3 0 DNA polymerase III, delta subunit PduV-EutP PF10662.4 AIN97941.1 - 0.33 10.4 2.8 43 3.5 0.0 4.4 6 0 0 6 6 5 0 Ethanolamine utilisation - propanediol utilisation AAA_21 PF13304.1 AIN97941.1 - 2.7 7.8 0.3 1.7e+02 1.9 0.0 3.6 5 0 0 5 5 3 0 AAA domain PhoH PF02562.11 AIN97941.1 - 5.6 6.1 13.1 3.7 6.7 0.0 4.6 6 0 0 6 6 4 0 PhoH-like protein DUF4154 PF13689.1 AIN97942.1 - 0.063 12.8 0.1 3.9 7.0 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4154) Enkurin PF13864.1 AIN97943.1 - 2.7e-25 88.4 7.2 5e-25 87.5 5.0 1.4 1 0 0 1 1 1 1 Calmodulin-binding BCDHK_Adom3 PF10436.4 AIN97944.1 - 1.4e-31 109.2 0.1 2.3e-31 108.5 0.1 1.3 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.21 AIN97944.1 - 5.6e-15 55.0 0.0 4.3e-14 52.1 0.0 2.2 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.1 AIN97944.1 - 1.4e-05 24.7 0.0 3.1e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase SPARC_Ca_bdg PF10591.4 AIN97944.1 - 0.086 12.8 0.1 0.18 11.8 0.1 1.6 1 0 0 1 1 1 0 Secreted protein acidic and rich in cysteine Ca binding region ZZ PF00569.12 AIN97945.1 - 8.4e-07 28.4 7.9 8.4e-07 28.4 5.5 2.8 2 0 0 2 2 2 1 Zinc finger, ZZ type RRM_5 PF13893.1 AIN97945.1 - 0.033 14.0 0.0 1.8 8.4 0.0 2.5 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) C1_1 PF00130.17 AIN97945.1 - 0.3 10.8 14.6 0.79 9.4 1.9 3.1 2 1 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) LRR_6 PF13516.1 AIN97946.1 - 6.4e-08 31.8 0.3 0.19 11.9 0.0 5.1 5 0 0 5 5 5 2 Leucine Rich repeat LRR_7 PF13504.1 AIN97946.1 - 4.9e-06 25.8 1.4 5.7 7.5 0.0 6.2 7 0 0 7 7 7 1 Leucine rich repeat LRR_1 PF00560.28 AIN97946.1 - 1.6e-05 24.2 0.5 40 4.7 0.0 5.8 5 1 0 5 5 5 0 Leucine Rich Repeat LRR_4 PF12799.2 AIN97946.1 - 0.0034 16.9 1.3 8.1 6.1 0.0 4.0 2 1 0 2 2 2 2 Leucine Rich repeats (2 copies) LRR_4 PF12799.2 AIN97948.1 - 5e-15 54.7 19.5 2.6e-07 30.1 1.7 5.5 2 2 4 6 6 6 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 AIN97948.1 - 3.9e-12 45.7 17.8 6.7e-06 25.7 0.3 4.2 2 2 2 4 4 4 4 Leucine rich repeat LRR_1 PF00560.28 AIN97948.1 - 7e-11 40.5 14.3 0.032 14.2 0.1 8.7 9 0 0 9 9 9 2 Leucine Rich Repeat LRR_7 PF13504.1 AIN97948.1 - 4.1e-08 32.1 23.7 0.019 15.0 0.2 8.1 8 0 0 8 8 8 3 Leucine rich repeat LRR_6 PF13516.1 AIN97948.1 - 3e-06 26.7 12.1 0.058 13.4 0.3 7.1 6 1 1 7 7 7 1 Leucine Rich repeat DUF3729 PF12526.3 AIN97948.1 - 0.11 13.8 5.4 1.8 9.9 0.1 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3729) Acetyltransf_13 PF13880.1 AIN97951.1 - 6.7e-23 80.2 0.1 1.7e-22 78.9 0.0 1.7 1 0 0 1 1 1 1 ESCO1/2 acetyl-transferase Acetyltransf_1 PF00583.19 AIN97951.1 - 0.054 13.5 0.0 0.24 11.4 0.0 2.0 2 0 0 2 2 2 0 Acetyltransferase (GNAT) family MFS_1 PF07690.11 AIN97952.1 - 8.8e-19 67.4 31.9 1.5e-12 46.8 7.8 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 AIN97952.1 - 0.0008 18.0 37.3 0.0016 17.1 11.2 2.6 2 1 0 2 2 2 2 Sugar (and other) transporter DUF2946 PF11162.3 AIN97954.1 - 7.1e-12 45.6 0.0 1.4e-11 44.6 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2946) CD34_antigen PF06365.7 AIN97954.1 - 0.013 15.1 0.0 0.02 14.5 0.0 1.3 1 0 0 1 1 1 0 CD34/Podocalyxin family DUF4307 PF14155.1 AIN97954.1 - 0.04 13.7 0.1 1.8 8.3 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4307) EphA2_TM PF14575.1 AIN97954.1 - 0.14 12.5 0.1 0.31 11.4 0.1 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Metallophos PF00149.23 AIN97955.1 - 0.0085 15.5 0.0 0.0085 15.5 0.0 1.9 3 0 0 3 3 3 1 Calcineurin-like phosphoesterase Metallophos PF00149.23 AIN97956.1 - 0.0035 16.7 0.0 0.0076 15.6 0.0 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Cellulase PF00150.13 AIN97956.1 - 0.083 12.0 0.0 0.14 11.3 0.0 1.2 1 0 0 1 1 1 0 Cellulase (glycosyl hydrolase family 5) NUDIX PF00293.23 AIN97957.1 - 9.6e-10 38.2 0.0 5.3e-06 26.1 0.0 3.4 2 1 0 2 2 2 2 NUDIX domain Rad1 PF02144.11 AIN97958.1 - 7.4e-08 31.4 0.0 2.1e-07 29.9 0.0 1.6 1 1 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 YwqJ-deaminase PF14431.1 AIN97960.1 - 0.13 12.1 7.0 0.054 13.3 1.4 2.9 3 0 0 3 3 3 0 YwqJ-like deaminase Methyltransf_8 PF05148.10 AIN97961.1 - 1.4e-53 181.7 0.0 1.9e-53 181.3 0.0 1.2 1 0 0 1 1 1 1 Hypothetical methyltransferase Methyltransf_11 PF08241.7 AIN97961.1 - 5.1e-08 33.2 0.0 2.1e-07 31.3 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 AIN97961.1 - 0.001 18.2 0.0 0.0028 16.8 0.0 1.7 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.1 AIN97961.1 - 0.011 15.4 0.0 0.025 14.3 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase domain TehB PF03848.9 AIN97961.1 - 0.023 13.8 0.0 0.056 12.6 0.0 1.7 2 0 0 2 2 2 0 Tellurite resistance protein TehB Methyltransf_31 PF13847.1 AIN97961.1 - 0.14 11.7 0.0 18 4.8 0.0 2.3 2 0 0 2 2 2 0 Methyltransferase domain DAO PF01266.19 AIN97962.1 - 1.1e-18 67.2 0.0 5e-10 38.8 0.0 2.7 2 1 0 2 2 2 2 FAD dependent oxidoreductase FAD_oxidored PF12831.2 AIN97962.1 - 2.2e-08 33.6 0.3 3.9e-08 32.7 0.2 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 AIN97962.1 - 7.5e-07 28.3 0.1 1.3e-06 27.5 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 AIN97962.1 - 1.2e-05 25.2 0.4 2.7e-05 24.1 0.3 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.17 AIN97962.1 - 1.5e-05 24.0 0.0 2.5e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 Glucose inhibited division protein A Pyr_redox_2 PF07992.9 AIN97962.1 - 0.0002 21.3 0.1 0.00049 20.0 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 AIN97962.1 - 0.00023 19.7 0.3 0.00036 19.1 0.2 1.2 1 0 0 1 1 1 1 HI0933-like protein Lycopene_cycl PF05834.7 AIN97962.1 - 0.013 14.4 0.1 0.024 13.5 0.0 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein Pyr_redox PF00070.22 AIN97962.1 - 0.016 15.6 0.4 0.056 13.8 0.1 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 AIN97962.1 - 0.038 14.0 0.1 0.09 12.8 0.1 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 AIN97962.1 - 0.17 10.9 0.1 0.3 10.1 0.1 1.3 1 0 0 1 1 1 0 Thi4 family AIG2_2 PF13772.1 AIN97963.1 - 2.2e-06 27.6 0.5 1.6e-05 24.9 0.1 2.6 3 0 0 3 3 3 1 AIG2-like family AIG2 PF06094.7 AIN97963.1 - 4.4e-05 23.8 0.2 0.0011 19.4 0.1 2.7 2 1 0 2 2 2 1 AIG2-like family Tubulin PF00091.20 AIN97964.1 - 5.3e-70 235.6 0.0 7.2e-70 235.1 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_2 PF13809.1 AIN97964.1 - 0.0019 17.1 0.0 0.0046 15.9 0.0 1.6 2 0 0 2 2 2 1 Tubulin like PPR_2 PF13041.1 AIN97965.1 - 1.1e-08 34.9 0.3 0.00045 20.1 0.0 4.4 3 1 2 5 5 5 4 PPR repeat family PPR PF01535.15 AIN97965.1 - 7e-07 28.8 0.0 1.8 8.6 0.0 4.4 5 0 0 5 5 5 3 PPR repeat PPR_3 PF13812.1 AIN97965.1 - 1.9e-06 27.6 0.6 0.00012 22.1 0.1 3.5 3 0 0 3 3 3 1 Pentatricopeptide repeat domain DNA_RNApol_7kD PF03604.8 AIN97966.1 - 0.021 14.2 1.2 0.037 13.5 0.8 1.5 1 1 0 1 1 1 0 DNA directed RNA polymerase, 7 kDa subunit A2L_zn_ribbon PF08792.5 AIN97966.1 - 0.055 12.9 0.3 0.11 11.9 0.2 1.5 1 0 0 1 1 1 0 A2L zinc ribbon domain TF_Zn_Ribbon PF08271.7 AIN97966.1 - 0.062 12.6 1.1 0.79 9.0 0.1 2.2 2 0 0 2 2 2 0 TFIIB zinc-binding zf-C3HC4_4 PF15227.1 AIN97966.1 - 0.084 12.7 0.7 0.14 12.0 0.5 1.4 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING PhnA_Zn_Ribbon PF08274.7 AIN97966.1 - 0.12 12.2 0.6 5.3 6.9 0.0 2.2 2 0 0 2 2 2 0 PhnA Zinc-Ribbon CTP_transf_2 PF01467.21 AIN97967.1 - 0.0004 20.4 0.0 0.0013 18.7 0.0 1.9 2 0 0 2 2 2 1 Cytidylyltransferase DUF4404 PF14357.1 AIN97968.1 - 0.018 15.4 2.0 0.25 11.7 0.0 3.3 4 0 0 4 4 4 0 Domain of unknown function (DUF4404) MORN PF02493.15 AIN97969.1 - 1.5e-16 59.0 18.3 3.8e-05 23.1 0.0 7.4 9 0 0 9 9 9 4 MORN repeat WW PF00397.21 AIN97969.1 - 0.043 13.6 0.2 0.13 12.1 0.1 1.9 1 0 0 1 1 1 0 WW domain RWD PF05773.17 AIN97971.1 - 4e-08 33.1 0.5 6.8e-08 32.3 0.4 1.3 1 0 0 1 1 1 1 RWD domain CTDII PF01556.13 AIN97972.1 - 1.7e-10 40.6 0.0 3.2e-07 30.1 0.0 3.3 3 0 0 3 3 3 2 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.14 AIN97972.1 - 3e-10 39.9 9.9 6e-10 39.0 6.9 1.5 1 0 0 1 1 1 1 DnaJ central domain CTP_synth_N PF06418.9 AIN97973.1 - 1.6e-108 362.0 0.0 2.2e-108 361.5 0.0 1.1 1 0 0 1 1 1 1 CTP synthase N-terminus GATase PF00117.23 AIN97973.1 - 1.9e-42 144.9 0.0 4.9e-42 143.5 0.0 1.7 2 0 0 2 2 2 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.8 AIN97973.1 - 5.9e-09 35.6 0.0 5.7e-08 32.4 0.0 2.1 1 1 0 2 2 2 1 Peptidase C26 CbiA PF01656.18 AIN97973.1 - 0.00036 20.0 0.0 0.00075 18.9 0.0 1.5 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain SH3BP5 PF05276.9 AIN97973.1 - 0.066 12.5 0.1 0.11 11.8 0.1 1.2 1 0 0 1 1 1 0 SH3 domain-binding protein 5 (SH3BP5) MORN PF02493.15 AIN97975.1 - 6.7e-18 63.2 40.2 0.00047 19.7 0.8 6.8 7 0 0 7 7 7 6 MORN repeat TFIIIC_sub6 PF10419.4 AIN97975.1 - 1.3 8.5 3.2 45 3.6 0.0 3.5 3 0 0 3 3 3 0 TFIIIC subunit Kinesin PF00225.18 AIN97979.1 - 3.9e-79 265.8 9.4 1.3e-74 250.8 0.0 3.2 3 1 0 3 3 3 2 Kinesin motor domain Fib_alpha PF08702.5 AIN97979.1 - 0.0019 18.3 9.4 0.95 9.5 2.2 3.7 3 0 0 3 3 3 3 Fibrinogen alpha/beta chain family DUF2353 PF09789.4 AIN97979.1 - 0.49 9.5 13.6 0.026 13.7 0.7 2.8 2 1 0 2 2 2 0 Uncharacterized coiled-coil protein (DUF2353) Spc24 PF08286.6 AIN97979.1 - 4.2 7.0 18.7 1.5 8.5 0.2 4.6 4 1 1 5 5 5 0 Spc24 subunit of Ndc80 DUF4140 PF13600.1 AIN97979.1 - 5 7.6 16.8 0.99 9.8 0.6 4.6 5 0 0 5 5 5 0 N-terminal domain of unknown function (DUF4140) TPR_14 PF13428.1 AIN97980.1 - 1.9e-07 31.0 8.5 2 9.2 0.0 5.8 5 1 1 6 6 6 4 Tetratricopeptide repeat TPR_11 PF13414.1 AIN97980.1 - 0.0022 17.6 0.8 0.04 13.5 0.3 3.0 2 2 0 2 2 2 1 TPR repeat Suf PF05843.9 AIN97980.1 - 0.0029 17.3 2.4 0.34 10.5 0.0 2.9 2 2 0 2 2 2 2 Suppressor of forked protein (Suf) TPR_16 PF13432.1 AIN97980.1 - 0.0046 17.6 4.1 0.83 10.4 0.0 4.6 3 2 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.12 AIN97980.1 - 0.023 14.5 4.4 21 5.3 0.1 4.9 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_1 PF00515.23 AIN97980.1 - 0.041 13.4 0.1 2.1 8.0 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_19 PF14559.1 AIN97980.1 - 0.052 13.8 0.4 7 7.0 0.0 3.7 3 1 0 3 3 3 0 Tetratricopeptide repeat HEAT PF02985.17 AIN97981.1 - 1.2e-30 102.7 41.8 0.00026 20.8 0.1 13.6 15 0 0 15 15 15 9 HEAT repeat HEAT_2 PF13646.1 AIN97981.1 - 7.5e-30 103.0 23.1 4.3e-07 30.1 0.8 7.7 2 1 6 8 8 8 8 HEAT repeats HEAT_EZ PF13513.1 AIN97981.1 - 2.1e-12 47.1 29.8 0.00081 19.8 0.1 9.6 8 2 2 10 10 10 4 HEAT-like repeat Vac14_Fab1_bd PF12755.2 AIN97981.1 - 1.1e-08 35.3 0.1 0.0014 18.9 0.0 5.8 2 1 3 7 7 7 1 Vacuolar 14 Fab1-binding region Adaptin_N PF01602.15 AIN97981.1 - 6e-05 21.5 6.6 0.0032 15.8 2.2 3.1 2 1 1 3 3 3 2 Adaptin N terminal region CLASP_N PF12348.3 AIN97981.1 - 0.00094 18.6 2.1 1 8.6 0.1 4.3 1 1 3 4 4 4 2 CLASP N terminal Cnd1 PF12717.2 AIN97981.1 - 0.0026 17.6 2.6 2.1 8.1 0.0 4.7 3 1 2 5 5 5 1 non-SMC mitotic condensation complex subunit 1 Arm PF00514.18 AIN97981.1 - 0.71 9.8 4.7 54 3.8 0.0 4.9 6 0 0 6 6 6 0 Armadillo/beta-catenin-like repeat HEAT_PBS PF03130.11 AIN97981.1 - 2.1 9.0 5.5 5.3 7.7 0.0 4.6 4 1 0 4 4 4 0 PBS lyase HEAT-like repeat Tfb2 PF03849.9 AIN97982.1 - 0.0021 16.8 0.5 0.0027 16.4 0.3 1.1 1 0 0 1 1 1 1 Transcription factor Tfb2 Acyl-CoA_dh_C PF12806.2 AIN97982.1 - 0.074 12.9 0.0 0.12 12.2 0.0 1.3 1 0 0 1 1 1 0 Acetyl-CoA dehydrogenase C-terminal like Sbi-IV PF11621.3 AIN97982.1 - 0.12 12.5 1.8 0.54 10.4 0.1 2.4 2 0 0 2 2 2 0 C3 binding domain 4 of IgG-bind protein SBI DUF775 PF05603.7 AIN97983.1 - 3.9e-35 121.2 0.0 4.7e-35 120.9 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF775) RecO_N PF11967.3 AIN97986.1 - 0.18 11.6 0.0 0.4 10.5 0.0 1.5 1 0 0 1 1 1 0 Recombination protein O N terminal Pkinase PF00069.20 AIN97987.1 - 1.3e-54 185.0 0.0 2.3e-54 184.2 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AIN97987.1 - 6.9e-36 123.6 0.0 1.1e-35 122.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase cNMP_binding PF00027.24 AIN97987.1 - 2.5e-15 56.0 0.0 1.6e-05 24.5 0.0 4.1 3 0 0 3 3 3 3 Cyclic nucleotide-binding domain PAS PF00989.19 AIN97987.1 - 5.4e-06 26.1 0.0 1.8e-05 24.5 0.0 1.8 1 0 0 1 1 1 1 PAS fold Kinase-like PF14531.1 AIN97987.1 - 0.00026 20.0 0.0 0.0032 16.4 0.0 2.1 2 0 0 2 2 2 1 Kinase-like PAS_9 PF13426.1 AIN97987.1 - 0.0045 17.3 0.0 0.012 15.9 0.0 1.7 1 0 0 1 1 1 1 PAS domain Popeye PF04831.8 AIN97987.1 - 2 8.1 0.0 5.2 6.7 0.0 1.6 2 0 0 2 2 2 0 Popeye protein conserved region Tubulin_3 PF14881.1 AIN97988.1 - 8.6e-05 22.0 0.0 0.00017 21.0 0.0 1.5 1 0 0 1 1 1 1 Tubulin domain Misat_Tub_SegII PF10644.4 AIN97988.1 - 0.0019 18.2 0.0 0.0044 17.0 0.0 1.6 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain TTL PF03133.10 AIN97989.1 - 1.1e-44 152.5 0.0 1.7e-42 145.3 0.0 2.2 1 1 0 1 1 1 1 Tubulin-tyrosine ligase family ScpA_ScpB PF02616.9 AIN97990.1 - 4.3 6.8 20.7 0.05 13.1 7.2 2.4 2 1 0 2 2 2 0 ScpA/B protein SNF5 PF04855.7 AIN97990.1 - 5.6 6.3 14.3 1 8.8 2.7 3.1 3 0 0 3 3 3 0 SNF5 / SMARCB1 / INI1 LUC7 PF03194.10 AIN97990.1 - 8.7 5.7 19.8 0.22 11.0 7.4 2.2 2 0 0 2 2 2 0 LUC7 N_terminus AAA PF00004.24 AIN97991.1 - 3.4e-49 166.4 0.0 9.5e-37 126.1 0.0 2.9 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 AIN97991.1 - 7.5e-12 46.1 0.2 2.5e-05 25.0 0.0 2.7 2 1 0 2 2 2 2 AAA domain AAA_19 PF13245.1 AIN97991.1 - 2.1e-08 33.8 0.7 0.002 17.8 0.0 2.9 3 0 0 3 3 2 2 Part of AAA domain AAA_22 PF13401.1 AIN97991.1 - 4.6e-08 33.2 1.6 0.027 14.6 0.7 4.3 2 2 0 2 2 2 2 AAA domain AAA_5 PF07728.9 AIN97991.1 - 1.8e-07 30.9 0.0 0.0027 17.4 0.0 3.0 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_18 PF13238.1 AIN97991.1 - 3.5e-07 30.5 0.1 0.017 15.3 0.0 2.7 3 0 0 3 3 2 2 AAA domain AAA_16 PF13191.1 AIN97991.1 - 8.7e-07 29.0 0.1 0.028 14.4 0.0 3.2 2 1 0 2 2 2 2 AAA ATPase domain Mg_chelatase PF01078.16 AIN97991.1 - 8.9e-06 25.0 0.0 0.003 16.7 0.0 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI TIP49 PF06068.8 AIN97991.1 - 1e-05 24.4 0.0 0.022 13.4 0.0 2.2 2 0 0 2 2 2 2 TIP49 C-terminus AAA_33 PF13671.1 AIN97991.1 - 9.7e-05 22.2 0.0 0.5 10.2 0.0 3.2 2 1 1 3 3 3 2 AAA domain Sigma54_activ_2 PF14532.1 AIN97991.1 - 0.0003 20.8 0.0 0.72 9.8 0.0 2.6 2 0 0 2 2 2 2 Sigma-54 interaction domain RNA_helicase PF00910.17 AIN97991.1 - 0.00041 20.4 0.0 0.52 10.5 0.0 2.7 2 0 0 2 2 2 1 RNA helicase RuvB_N PF05496.7 AIN97991.1 - 0.00042 19.4 0.0 0.083 11.9 0.0 2.5 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_3 PF07726.6 AIN97991.1 - 0.00057 19.5 0.0 0.35 10.4 0.0 2.5 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 AIN97991.1 - 0.0008 18.9 0.0 0.36 10.2 0.0 2.5 2 0 0 2 2 2 1 Sigma-54 interaction domain IstB_IS21 PF01695.12 AIN97991.1 - 0.00095 18.6 0.0 0.031 13.7 0.0 2.9 3 0 0 3 3 3 1 IstB-like ATP binding protein AAA_28 PF13521.1 AIN97991.1 - 0.0012 18.8 0.0 1.4 8.8 0.0 2.5 2 0 0 2 2 2 2 AAA domain NACHT PF05729.7 AIN97991.1 - 0.0013 18.3 0.1 0.66 9.6 0.0 3.6 3 1 0 3 3 3 1 NACHT domain Zeta_toxin PF06414.7 AIN97991.1 - 0.0014 17.8 0.0 1.7 7.6 0.0 2.4 2 0 0 2 2 2 2 Zeta toxin AAA_2 PF07724.9 AIN97991.1 - 0.0029 17.5 0.0 0.014 15.2 0.0 2.1 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) KTI12 PF08433.5 AIN97991.1 - 0.0042 16.3 0.0 3.3 6.8 0.0 2.8 3 0 0 3 3 3 1 Chromatin associated protein KTI12 DUF2075 PF09848.4 AIN97991.1 - 0.0045 15.9 0.1 2.4 7.0 0.0 2.5 2 1 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) ABC_tran PF00005.22 AIN97991.1 - 0.0071 16.6 0.1 0.62 10.3 0.0 3.1 2 1 1 3 3 3 1 ABC transporter AAA_30 PF13604.1 AIN97991.1 - 0.0074 15.8 0.1 5.2 6.5 0.0 2.9 3 1 0 3 3 2 0 AAA domain T2SE PF00437.15 AIN97991.1 - 0.0086 14.9 0.0 2.1 7.1 0.0 2.4 2 0 0 2 2 2 1 Type II/IV secretion system protein CDC48_N PF02359.13 AIN97991.1 - 0.013 15.4 0.0 0.049 13.5 0.0 1.9 1 1 0 1 1 1 0 Cell division protein 48 (CDC48), N-terminal domain AAA_11 PF13086.1 AIN97991.1 - 0.028 13.9 0.0 1.5 8.3 0.0 2.6 2 1 0 2 2 2 0 AAA domain PhoH PF02562.11 AIN97991.1 - 0.032 13.4 0.0 0.54 9.4 0.0 2.4 2 0 0 2 2 2 0 PhoH-like protein KaiC PF06745.8 AIN97991.1 - 0.036 13.1 0.1 2.9 6.9 0.1 2.5 2 0 0 2 2 2 0 KaiC AAA_25 PF13481.1 AIN97991.1 - 0.06 12.7 4.3 8.7 5.6 0.1 3.7 3 1 1 4 4 4 0 AAA domain AAA_29 PF13555.1 AIN97991.1 - 0.075 12.5 0.4 6.5 6.3 0.0 2.6 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_24 PF13479.1 AIN97991.1 - 0.095 12.2 0.4 1.2 8.6 0.1 2.5 3 0 0 3 3 2 0 AAA domain ACPS PF01648.15 AIN97993.1 - 1.5e-09 37.7 0.0 3e-09 36.7 0.0 1.5 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily SCO1-SenC PF02630.9 AIN97994.1 - 1.8e-29 102.5 0.0 9.3e-28 97.0 0.0 2.4 1 1 0 1 1 1 1 SCO1/SenC Thioredoxin_8 PF13905.1 AIN97994.1 - 0.084 12.9 0.0 0.18 11.9 0.0 1.5 1 0 0 1 1 1 0 Thioredoxin-like TruD PF01142.13 AIN97995.1 - 2.3e-15 56.1 0.0 5.2e-13 48.4 0.0 3.2 3 1 0 3 3 3 2 tRNA pseudouridine synthase D (TruD) DEAD PF00270.24 AIN97997.1 - 3e-27 95.1 0.5 4.1e-15 55.6 0.0 3.1 3 0 0 3 3 3 2 DEAD/DEAH box helicase Helicase_C PF00271.26 AIN97997.1 - 2.5e-14 52.9 0.0 6.2e-14 51.6 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 AIN97997.1 - 9e-08 32.1 0.0 8.8e-07 28.9 0.0 2.1 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_22 PF13401.1 AIN97997.1 - 0.28 11.3 2.7 2.6 8.1 0.1 2.8 2 1 0 2 2 2 0 AAA domain Elf1 PF05129.8 AIN97998.1 - 2.5e-21 75.1 0.4 4.3e-21 74.3 0.3 1.3 1 0 0 1 1 1 1 Transcription elongation factor Elf1 like zinc_ribbon_5 PF13719.1 AIN97998.1 - 0.02 14.4 1.0 0.054 13.0 0.7 1.7 1 0 0 1 1 1 0 zinc-ribbon domain Lar_restr_allev PF14354.1 AIN97998.1 - 0.054 13.8 0.1 0.15 12.3 0.1 1.8 1 0 0 1 1 1 0 Restriction alleviation protein Lar zinc_ribbon_4 PF13717.1 AIN97998.1 - 0.084 12.5 0.9 0.24 11.1 0.6 1.8 1 0 0 1 1 1 0 zinc-ribbon domain Elf1 PF05129.8 AIN97999.1 - 8.4e-09 35.0 0.4 3.4e-08 33.0 0.3 1.9 1 1 0 1 1 1 1 Transcription elongation factor Elf1 like TF_Zn_Ribbon PF08271.7 AIN97999.1 - 0.94 8.8 4.5 2.4 7.5 3.1 1.7 1 0 0 1 1 1 0 TFIIB zinc-binding Ribonuclease_3 PF00636.21 AIN98000.1 - 0.0015 18.9 0.0 0.0039 17.6 0.0 1.7 1 0 0 1 1 1 1 Ribonuclease III domain DUF755 PF05501.6 AIN98001.1 - 0.2 11.7 6.3 0.53 10.3 4.4 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF755) AATF-Che1 PF13339.1 AIN98002.1 - 2.3e-27 95.7 3.7 2.8e-26 92.2 0.0 3.5 4 0 0 4 4 4 1 Apoptosis antagonizing transcription factor TRAUB PF08164.7 AIN98002.1 - 0.021 14.9 0.1 0.021 14.9 0.0 2.7 3 0 0 3 3 3 0 Apoptosis-antagonizing transcription factor, C-terminal BUD22 PF09073.5 AIN98003.1 - 0.74 8.8 20.5 1.2 8.1 14.2 1.2 1 0 0 1 1 1 0 BUD22 DUF4379 PF14311.1 AIN98005.1 - 2.8e-12 46.2 9.8 2.8e-07 30.2 3.3 2.8 2 0 0 2 2 2 2 Domain of unknown function (DUF4379) Zn-ribbon_8 PF09723.5 AIN98005.1 - 0.1 12.5 2.9 0.26 11.2 2.0 1.6 1 0 0 1 1 1 0 Zinc ribbon domain SprT-like PF10263.4 AIN98005.1 - 0.31 10.6 5.6 0.064 12.9 0.4 2.3 3 0 0 3 3 3 0 SprT-like family Pkinase PF00069.20 AIN98006.1 - 2.8e-48 164.3 1.4 5.2e-32 111.0 0.5 3.3 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 AIN98006.1 - 2.3e-31 108.8 0.0 4.3e-31 107.9 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 AIN98006.1 - 0.0025 16.8 0.0 0.0053 15.7 0.0 1.4 1 0 0 1 1 1 1 Kinase-like PAS_9 PF13426.1 AIN98006.1 - 0.06 13.7 0.0 8.2 6.8 0.0 2.9 3 0 0 3 3 3 0 PAS domain PAS_8 PF13188.1 AIN98006.1 - 0.14 12.0 0.0 0.55 10.1 0.0 2.0 1 0 0 1 1 1 0 PAS domain Kdo PF06293.9 AIN98006.1 - 0.22 10.5 0.0 0.45 9.5 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family ARD PF03079.9 AIN98007.1 - 2.4e-36 125.0 0.0 3.6e-36 124.4 0.0 1.3 1 0 0 1 1 1 1 ARD/ARD' family DUF953 PF06110.6 AIN98007.1 - 1.2e-13 50.5 0.0 2.1e-13 49.7 0.0 1.3 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF953) Cupin_2 PF07883.6 AIN98007.1 - 3.1e-08 32.9 0.0 5.3e-08 32.2 0.0 1.4 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.14 AIN98007.1 - 3.2e-07 30.1 0.1 9e-07 28.6 0.0 1.9 2 0 0 2 2 2 1 AraC-like ligand binding domain Cupin_6 PF12852.2 AIN98007.1 - 0.056 13.0 0.0 0.088 12.4 0.0 1.3 1 0 0 1 1 1 0 Cupin Glutaredoxin PF00462.19 AIN98010.1 - 2e-11 43.6 0.0 2.8e-11 43.2 0.0 1.2 1 0 0 1 1 1 1 Glutaredoxin SH3BGR PF04908.10 AIN98010.1 - 0.049 13.5 0.0 0.06 13.2 0.0 1.2 1 0 0 1 1 1 0 SH3-binding, glutamic acid-rich protein Thioredoxin_3 PF13192.1 AIN98010.1 - 0.053 13.3 0.0 0.074 12.8 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin domain DUF1143 PF06608.6 AIN98016.1 - 0.11 12.4 0.4 0.2 11.6 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1143) PAT1 PF09770.4 AIN98016.1 - 1.9 6.6 22.2 2.3 6.3 15.4 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 TFIIA PF03153.8 AIN98016.1 - 8.3 6.1 12.4 12 5.6 8.6 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit zf-RING_2 PF13639.1 AIN98017.1 - 0.00033 20.4 3.5 0.00081 19.1 2.4 1.7 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 AIN98017.1 - 0.0082 16.2 8.2 0.019 15.0 5.7 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_5 PF14634.1 AIN98017.1 - 0.036 13.7 5.9 0.16 11.7 4.1 2.2 1 1 0 1 1 1 0 zinc-RING finger domain zf-C3HC4_2 PF13923.1 AIN98017.1 - 0.036 14.0 3.2 0.12 12.4 2.2 2.0 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 AIN98017.1 - 5 6.8 7.8 6 6.6 4.0 2.2 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) AAA_17 PF13207.1 AIN98018.1 - 0.009 16.8 0.0 0.027 15.2 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 AIN98018.1 - 0.0093 16.1 0.3 0.05 13.7 0.0 2.4 3 0 0 3 3 3 1 AAA domain AAA PF00004.24 AIN98018.1 - 0.0098 16.0 0.0 0.021 15.0 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Arch_ATPase PF01637.13 AIN98018.1 - 0.68 9.5 0.0 1.2 8.7 0.0 1.3 1 0 0 1 1 1 0 Archaeal ATPase MORN PF02493.15 AIN98019.1 - 5.9e-08 31.9 11.4 0.006 16.2 0.3 4.0 3 0 0 3 3 3 3 MORN repeat PI3_PI4_kinase PF00454.22 AIN98021.1 - 8e-44 149.8 0.1 2e-43 148.5 0.1 1.7 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FAT PF02259.18 AIN98021.1 - 9.1e-33 113.6 3.4 9.1e-33 113.6 2.4 2.3 3 1 0 3 3 3 1 FAT domain FATC PF02260.15 AIN98021.1 - 7.1e-10 38.1 0.0 1.7e-09 36.9 0.0 1.7 1 0 0 1 1 1 1 FATC domain TFCD_C PF12612.3 AIN98021.1 - 0.00014 21.3 2.4 0.00035 20.0 0.1 3.0 2 0 0 2 2 2 1 Tubulin folding cofactor D C terminal HEAT PF02985.17 AIN98021.1 - 0.0028 17.5 5.1 39 4.6 0.0 7.2 7 0 0 7 7 7 0 HEAT repeat V-ATPase_H_C PF11698.3 AIN98021.1 - 0.05 13.5 0.3 7.7 6.4 0.0 3.2 2 0 0 2 2 2 0 V-ATPase subunit H DnaJ PF00226.26 AIN98022.1 - 5.6e-19 67.6 0.4 5.6e-19 67.6 0.3 2.3 2 0 0 2 2 2 1 DnaJ domain Myb_DNA-bind_6 PF13921.1 AIN98022.1 - 0.017 15.1 16.1 0.029 14.4 0.3 4.4 4 0 0 4 4 4 0 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 AIN98022.1 - 0.078 13.0 11.3 0.6 10.2 0.1 4.0 4 0 0 4 4 4 0 Myb-like DNA-binding domain YIF1 PF03878.10 AIN98023.1 - 4e-26 91.6 13.2 4.7e-25 88.1 9.1 2.0 1 1 0 1 1 1 1 YIF1 PRP38 PF03371.10 AIN98024.1 - 2.3e-13 50.1 0.0 3.3e-13 49.6 0.0 1.1 1 0 0 1 1 1 1 PRP38 family Peptidase_C2 PF00648.16 AIN98026.1 - 2.5e-54 184.3 0.0 3.7e-54 183.7 0.0 1.2 1 0 0 1 1 1 1 Calpain family cysteine protease DUF1935 PF09149.5 AIN98026.1 - 6.4e-34 116.0 0.1 1.3e-33 115.0 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1935) Peptidase_C2 PF00648.16 AIN98027.1 - 2.2e-54 184.4 0.0 3.4e-54 183.8 0.0 1.2 1 0 0 1 1 1 1 Calpain family cysteine protease DUF1935 PF09149.5 AIN98027.1 - 5.9e-34 116.1 0.1 1.2e-33 115.1 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1935) Peptidase_C2 PF00648.16 AIN98028.1 - 2.1e-46 158.3 0.0 4.5e-46 157.2 0.0 1.5 2 0 0 2 2 2 1 Calpain family cysteine protease DUF1935 PF09149.5 AIN98028.1 - 4.3e-33 113.4 0.1 8.8e-33 112.4 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1935) Peptidase_C2 PF00648.16 AIN98029.1 - 1.2e-38 132.8 0.0 1.9e-38 132.1 0.0 1.2 1 0 0 1 1 1 1 Calpain family cysteine protease DUF1935 PF09149.5 AIN98029.1 - 7.7e-25 86.8 0.0 1.6e-24 85.8 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1935) DUF1935 PF09149.5 AIN98030.1 - 2.8e-09 36.8 0.0 5.7e-09 35.8 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1935) Peptidase_C2 PF00648.16 AIN98031.1 - 2.6e-26 92.3 0.0 4.8e-26 91.4 0.0 1.4 1 1 0 1 1 1 1 Calpain family cysteine protease DUF1935 PF09149.5 AIN98032.1 - 1.6e-26 92.2 0.0 2.1e-26 91.9 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1935) DUF1935 PF09149.5 AIN98033.1 - 6.9e-29 99.8 0.0 7.9e-29 99.6 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1935) Raptor_N PF14538.1 AIN98034.1 - 4.5e-11 42.8 0.0 1e-10 41.6 0.0 1.6 1 0 0 1 1 1 1 Raptor N-terminal CASPase like domain DUF1935 PF09149.5 AIN98035.1 - 1.5e-29 101.9 0.0 2.6e-29 101.2 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1935) DUF1935 PF09149.5 AIN98036.1 - 5.8e-05 23.0 0.0 0.36 10.8 0.0 2.5 2 0 0 2 2 2 2 Domain of unknown function (DUF1935) DUF1935 PF09149.5 AIN98037.1 - 2.4e-07 30.6 0.0 3e-07 30.3 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1935) DUF1935 PF09149.5 AIN98038.1 - 9.2e-29 99.4 0.0 1.2e-28 99.1 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1935) TMA7 PF09072.5 AIN98038.1 - 0.04 14.3 2.1 0.065 13.7 1.4 1.3 1 0 0 1 1 1 0 Translation machinery associated TMA7 NAP PF00956.13 AIN98039.1 - 8.2e-21 74.2 0.4 1.1e-20 73.8 0.3 1.1 1 0 0 1 1 1 1 Nucleosome assembly protein (NAP) Mst1_SARAH PF11629.3 AIN98039.1 - 0.0013 18.4 0.2 0.0034 17.1 0.2 1.7 1 0 0 1 1 1 1 C terminal SARAH domain of Mst1 Sipho_Gp157 PF05565.6 AIN98039.1 - 7 6.2 9.9 12 5.4 0.7 2.3 2 0 0 2 2 2 0 Siphovirus Gp157 DUF1935 PF09149.5 AIN98040.1 - 1.4e-33 114.9 0.1 1.7e-33 114.6 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1935) DUF1935 PF09149.5 AIN98041.1 - 8.8e-39 131.6 0.2 1e-38 131.4 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1935) Pkinase PF00069.20 AIN98043.1 - 3.5e-32 111.5 0.0 4.9e-32 111.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AIN98043.1 - 2e-14 53.2 0.0 4.3e-14 52.2 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 AIN98043.1 - 3e-06 26.4 0.0 0.00083 18.3 0.0 2.1 2 0 0 2 2 2 2 Kinase-like Adaptin_N PF01602.15 AIN98044.1 - 5.3e-62 209.8 6.3 7.7e-62 209.2 4.4 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Coatomer_b_Cpla PF14806.1 AIN98044.1 - 1.3e-37 128.3 0.5 6.3e-36 122.9 0.3 2.6 1 1 0 1 1 1 1 Coatomer beta subunit appendage platform Coatamer_beta_C PF07718.7 AIN98044.1 - 1.9e-37 128.0 0.0 4.4e-37 126.8 0.0 1.6 1 0 0 1 1 1 1 Coatomer beta C-terminal region HEAT_2 PF13646.1 AIN98044.1 - 4.6e-07 30.0 12.8 0.085 13.1 0.0 5.6 4 3 2 6 6 6 3 HEAT repeats HEAT PF02985.17 AIN98044.1 - 6.3e-07 28.9 1.4 0.31 11.2 0.0 5.4 5 0 0 5 5 5 2 HEAT repeat Cnd1 PF12717.2 AIN98044.1 - 0.00037 20.3 6.0 0.36 10.6 0.1 2.9 2 1 0 2 2 2 2 non-SMC mitotic condensation complex subunit 1 RNase_PH PF01138.16 AIN98045.1 - 0.0018 18.5 0.1 0.0065 16.7 0.0 2.0 1 1 0 1 1 1 1 3' exoribonuclease family, domain 1 Peptidase_C25_C PF03785.9 AIN98045.1 - 0.04 13.7 1.7 0.11 12.3 1.1 1.6 1 0 0 1 1 1 0 Peptidase family C25, C terminal ig-like domain PUF PF00806.14 AIN98046.1 - 2.1e-19 67.8 0.0 0.0035 16.7 0.0 4.5 4 0 0 4 4 4 4 Pumilio-family RNA binding repeat IncA PF04156.9 AIN98047.1 - 0.072 12.6 9.4 0.21 11.1 0.1 3.1 3 0 0 3 3 3 0 IncA protein AraC_binding PF02311.14 AIN98047.1 - 3.1 7.4 5.7 3.8 7.2 0.1 2.5 2 0 0 2 2 2 0 AraC-like ligand binding domain Macoilin PF09726.4 AIN98048.1 - 0.014 13.7 11.9 0.12 10.5 2.4 2.0 1 1 1 2 2 2 0 Transmembrane protein Cep57_CLD_2 PF14197.1 AIN98048.1 - 0.099 12.6 12.8 2.4 8.1 0.3 3.5 3 0 0 3 3 3 0 Centrosome localisation domain of PPC89 GCN5L1 PF06320.8 AIN98048.1 - 0.1 12.4 12.3 0.28 10.9 0.5 3.2 3 0 0 3 3 3 0 GCN5-like protein 1 (GCN5L1) Exonuc_VII_L PF02601.10 AIN98048.1 - 0.1 11.7 6.9 0.22 10.6 1.6 2.1 2 0 0 2 2 2 0 Exonuclease VII, large subunit Tropomyosin_1 PF12718.2 AIN98048.1 - 0.17 11.6 13.3 0.55 10.0 0.3 3.4 3 0 0 3 3 3 0 Tropomyosin like Sipho_Gp157 PF05565.6 AIN98048.1 - 0.2 11.2 3.5 1.1 8.8 0.4 2.3 2 0 0 2 2 2 0 Siphovirus Gp157 Tropomyosin PF00261.15 AIN98048.1 - 0.44 9.6 14.9 2.6 7.0 1.7 3.4 4 0 0 4 4 4 0 Tropomyosin TMF_DNA_bd PF12329.3 AIN98048.1 - 0.65 9.8 8.8 2.4 8.0 0.7 3.5 3 0 0 3 3 3 0 TATA element modulatory factor 1 DNA binding bZIP_1 PF00170.16 AIN98048.1 - 1.1 9.2 11.5 0.31 11.0 1.9 3.0 3 0 0 3 3 2 0 bZIP transcription factor Striatin PF08232.7 AIN98048.1 - 1.2 9.4 14.6 0.17 12.1 0.9 2.9 2 2 1 3 3 3 0 Striatin family PRKCSH-like PF12999.2 AIN98048.1 - 2.7 7.5 4.7 0.52 9.8 0.0 2.1 3 0 0 3 3 3 0 Glucosidase II beta subunit-like CDC37_N PF03234.9 AIN98048.1 - 3 8.1 5.2 7 6.9 0.1 2.9 3 0 0 3 3 3 0 Cdc37 N terminal kinase binding DivIC PF04977.10 AIN98048.1 - 7.4 6.1 14.6 0.53 9.7 0.1 3.1 4 0 0 4 4 4 0 Septum formation initiator DUF4164 PF13747.1 AIN98048.1 - 8.9 6.5 18.6 2.9 8.0 0.8 3.8 3 1 0 3 3 3 0 Domain of unknown function (DUF4164) Arm PF00514.18 AIN98049.1 - 8.1e-36 120.6 20.8 1.4e-05 24.7 0.0 8.7 9 0 0 9 9 9 7 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 AIN98049.1 - 2.6e-22 78.9 16.2 5.9e-06 26.4 0.1 5.0 2 1 3 5 5 5 5 HEAT repeats HEAT PF02985.17 AIN98049.1 - 5.8e-19 66.4 11.8 0.0047 16.9 0.0 8.0 9 0 0 9 9 8 5 HEAT repeat HEAT_EZ PF13513.1 AIN98049.1 - 2.6e-14 53.2 22.0 0.0018 18.7 0.3 6.6 5 1 2 7 7 7 5 HEAT-like repeat Adaptin_N PF01602.15 AIN98049.1 - 2.6e-12 45.8 1.2 1.8e-08 33.1 1.7 3.0 2 1 0 2 2 2 2 Adaptin N terminal region Proteasom_PSMB PF10508.4 AIN98049.1 - 5e-09 34.9 2.8 6.5e-05 21.3 0.4 3.6 1 1 2 3 3 3 3 Proteasome non-ATPase 26S subunit DNA_alkylation PF08713.6 AIN98049.1 - 4.6e-08 32.8 0.1 0.095 12.1 0.0 4.2 2 1 1 4 4 4 3 DNA alkylation repair enzyme Cnd1 PF12717.2 AIN98049.1 - 1.6e-07 31.3 0.5 0.00051 19.9 0.1 3.7 1 1 2 3 3 3 2 non-SMC mitotic condensation complex subunit 1 CLASP_N PF12348.3 AIN98049.1 - 0.00027 20.3 1.1 0.4 9.9 0.2 3.3 2 1 1 3 3 3 2 CLASP N terminal HEAT_PBS PF03130.11 AIN98049.1 - 0.0017 18.6 11.3 0.12 12.8 0.3 5.7 7 0 0 7 7 5 1 PBS lyase HEAT-like repeat V-ATPase_H_C PF11698.3 AIN98049.1 - 0.0021 17.9 0.5 0.24 11.3 0.1 3.8 4 0 0 4 4 4 1 V-ATPase subunit H Vac14_Fab1_bd PF12755.2 AIN98049.1 - 0.012 16.0 0.2 0.58 10.5 0.0 3.3 1 1 3 4 4 4 0 Vacuolar 14 Fab1-binding region DUF3731 PF12531.3 AIN98049.1 - 0.014 14.9 3.0 2.8 7.4 0.1 3.5 2 1 1 3 3 3 0 DNA-K related protein XPC-binding PF09280.6 AIN98049.1 - 0.034 13.6 0.0 31 4.1 0.0 4.0 3 0 0 3 3 3 0 XPC-binding domain OHCU_decarbox PF09349.5 AIN98049.1 - 0.08 13.2 1.7 10 6.3 0.0 3.4 2 1 1 3 3 3 0 OHCU decarboxylase DUF4244 PF14029.1 AIN98050.1 - 0.1 11.7 1.5 0.23 10.5 0.4 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF4244) SET PF00856.23 AIN98052.1 - 0.011 15.9 0.0 0.14 12.4 0.0 2.1 1 1 0 1 1 1 0 SET domain ubiquitin PF00240.18 AIN98054.1 - 0.0025 17.1 0.0 0.87 9.0 0.0 3.3 4 0 0 4 4 4 1 Ubiquitin family Spc7 PF08317.6 AIN98054.1 - 0.13 10.8 1.7 0.26 9.9 1.2 1.4 1 0 0 1 1 1 0 Spc7 kinetochore protein Rabaptin PF03528.10 AIN98054.1 - 0.22 11.4 3.4 0.56 10.1 2.3 1.7 1 0 0 1 1 1 0 Rabaptin DUF2802 PF10975.3 AIN98054.1 - 4 7.2 7.9 3 7.6 2.9 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF2802) DUF591 PF04569.9 AIN98057.1 - 0.079 13.0 0.0 0.22 11.5 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function Myotub-related PF06602.9 AIN98058.1 - 8.4e-85 284.6 0.0 1.7e-84 283.6 0.0 1.5 1 1 0 1 1 1 1 Myotubularin-like phosphatase domain Y_phosphatase3 PF13350.1 AIN98058.1 - 0.0061 16.8 0.0 0.013 15.7 0.0 1.5 1 0 0 1 1 1 1 Tyrosine phosphatase family FYVE_2 PF02318.11 AIN98058.1 - 0.092 12.6 8.4 0.24 11.2 5.8 1.7 1 0 0 1 1 1 0 FYVE-type zinc finger C1_4 PF07975.7 AIN98058.1 - 0.18 11.8 11.2 0.55 10.2 7.8 1.8 1 0 0 1 1 1 0 TFIIH C1-like domain FYVE PF01363.16 AIN98058.1 - 0.25 11.2 12.1 0.78 9.6 8.4 1.8 1 0 0 1 1 1 0 FYVE zinc finger HEAT_EZ PF13513.1 AIN98059.1 - 0.0041 17.5 1.1 0.043 14.3 0.1 3.3 3 0 0 3 3 3 1 HEAT-like repeat DUF4456 PF14644.1 AIN98062.1 - 5.7e-11 42.0 0.0 5.7e-11 42.0 0.0 4.1 4 0 0 4 4 4 1 Domain of unknown function (DUF4456) DUF4455 PF14643.1 AIN98062.1 - 4.8e-07 28.7 1.5 4.8e-07 28.7 1.0 4.3 4 1 0 4 4 4 2 Domain of unknown function (DUF4455) EMP24_GP25L PF01105.19 AIN98062.1 - 0.19 11.4 1.9 26 4.4 1.0 3.4 3 0 0 3 3 3 0 emp24/gp25L/p24 family/GOLD AAA PF00004.24 AIN98063.1 - 3.7e-25 88.6 0.0 2.3e-24 86.0 0.0 2.3 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 AIN98063.1 - 0.0002 21.5 0.6 0.0028 17.7 0.0 3.0 3 1 0 3 3 3 1 AAA domain ABC_tran PF00005.22 AIN98063.1 - 0.0002 21.6 0.0 0.00068 19.9 0.0 1.9 2 0 0 2 2 2 1 ABC transporter AAA_16 PF13191.1 AIN98063.1 - 0.00021 21.3 0.4 0.00021 21.3 0.3 3.8 2 2 0 3 3 3 1 AAA ATPase domain NACHT PF05729.7 AIN98063.1 - 0.01 15.5 2.9 0.62 9.7 0.0 3.5 2 2 0 2 2 2 0 NACHT domain AAA_17 PF13207.1 AIN98063.1 - 0.011 16.5 0.0 0.03 15.1 0.0 1.8 1 0 0 1 1 1 0 AAA domain KAP_NTPase PF07693.9 AIN98063.1 - 0.025 13.6 0.0 0.72 8.7 0.0 2.6 2 1 1 3 3 3 0 KAP family P-loop domain AAA_33 PF13671.1 AIN98063.1 - 0.027 14.3 0.7 0.084 12.7 0.0 2.2 3 0 0 3 3 3 0 AAA domain AAA_29 PF13555.1 AIN98063.1 - 0.032 13.7 0.0 0.099 12.1 0.0 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_5 PF07728.9 AIN98063.1 - 0.054 13.2 0.2 0.35 10.6 0.0 2.5 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Zeta_toxin PF06414.7 AIN98063.1 - 0.072 12.1 0.2 0.29 10.1 0.0 2.0 2 0 0 2 2 2 0 Zeta toxin AAA_14 PF13173.1 AIN98063.1 - 0.11 12.4 0.0 0.24 11.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 AIN98063.1 - 0.15 12.4 0.0 0.28 11.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain Arch_ATPase PF01637.13 AIN98063.1 - 0.17 11.5 0.0 0.44 10.2 0.0 1.6 2 0 0 2 2 1 0 Archaeal ATPase AAA_21 PF13304.1 AIN98063.1 - 0.31 10.9 0.0 0.45 10.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain RabGAP-TBC PF00566.13 AIN98064.1 - 5.5e-17 61.9 0.1 1.1e-16 60.9 0.1 1.5 1 0 0 1 1 1 1 Rab-GTPase-TBC domain SGS PF05002.10 AIN98065.1 - 8.4e-30 102.3 0.6 1.3e-29 101.7 0.4 1.3 1 0 0 1 1 1 1 SGS domain CS PF04969.11 AIN98065.1 - 2.4e-06 27.9 0.0 3.9e-06 27.3 0.0 1.3 1 0 0 1 1 1 1 CS domain Ribosomal_S17 PF00366.15 AIN98066.1 - 8.6e-26 89.7 1.5 8.6e-26 89.7 1.0 2.0 2 0 0 2 2 2 1 Ribosomal protein S17 DnaB_2 PF07261.6 AIN98067.1 - 0.02 14.4 0.0 0.037 13.6 0.0 1.4 1 0 0 1 1 1 0 Replication initiation and membrane attachment Brix PF04427.13 AIN98068.1 - 3e-32 111.8 0.0 4.5e-32 111.2 0.0 1.2 1 0 0 1 1 1 1 Brix domain Peptidase_C50 PF03568.12 AIN98069.1 - 4.3e-28 98.0 0.1 2.4e-15 56.1 0.0 3.2 3 0 0 3 3 3 3 Peptidase family C50 CHAT PF12770.2 AIN98069.1 - 1.6e-08 34.0 0.5 0.0003 20.0 0.1 2.8 2 0 0 2 2 2 2 CHAT domain SNAP PF14938.1 AIN98070.1 - 1.1e-58 198.6 12.1 1.3e-58 198.4 8.4 1.0 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP TPR_12 PF13424.1 AIN98070.1 - 6.9e-10 38.7 4.4 2.4e-07 30.5 1.2 2.9 3 0 0 3 3 2 2 Tetratricopeptide repeat TPR_11 PF13414.1 AIN98070.1 - 9.7e-07 28.3 6.5 0.00014 21.4 1.7 3.0 2 1 0 2 2 2 2 TPR repeat TPR_8 PF13181.1 AIN98070.1 - 0.0011 18.6 10.3 0.0011 18.5 0.8 4.0 4 1 0 4 4 3 1 Tetratricopeptide repeat Foie-gras_1 PF11817.3 AIN98070.1 - 0.0028 17.1 0.5 0.0028 17.1 0.4 2.0 2 0 0 2 2 2 1 Foie gras liver health family 1 TPR_7 PF13176.1 AIN98070.1 - 0.012 15.3 1.7 1.8 8.5 0.0 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF1033 PF06279.6 AIN98070.1 - 0.032 14.0 0.6 0.032 14.0 0.4 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF1033) TPR_1 PF00515.23 AIN98070.1 - 0.053 13.1 0.7 0.053 13.1 0.5 4.6 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_6 PF13174.1 AIN98070.1 - 0.062 13.7 20.3 2.4 8.7 0.1 5.7 4 3 0 5 5 5 0 Tetratricopeptide repeat BAR PF03114.13 AIN98070.1 - 0.16 11.4 3.1 0.63 9.5 0.7 2.4 1 1 1 2 2 2 0 BAR domain TPR_2 PF07719.12 AIN98070.1 - 0.23 11.4 12.8 2 8.5 0.2 5.5 4 2 0 5 5 5 0 Tetratricopeptide repeat TPR_19 PF14559.1 AIN98070.1 - 0.25 11.6 12.2 0.36 11.2 0.7 3.4 3 1 1 4 4 3 0 Tetratricopeptide repeat Apc3 PF12895.2 AIN98070.1 - 0.4 10.8 5.3 0.99 9.5 1.0 2.8 3 1 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.1 AIN98070.1 - 0.71 10.6 7.6 9.8 6.9 0.1 3.7 2 1 1 4 4 4 0 Tetratricopeptide repeat MIT PF04212.13 AIN98070.1 - 1.1 9.2 6.8 3.3 7.6 0.0 4.1 3 1 1 4 4 4 0 MIT (microtubule interacting and transport) domain TPR_21 PF09976.4 AIN98070.1 - 3.1 7.7 8.6 7 6.5 1.9 2.5 1 1 1 2 2 2 0 Tetratricopeptide repeat tRNA_U5-meth_tr PF05958.6 AIN98072.1 - 2.1e-18 66.1 0.0 2e-17 62.9 0.0 2.0 1 1 0 1 1 1 1 tRNA (Uracil-5-)-methyltransferase Methyltransf_31 PF13847.1 AIN98072.1 - 1.1e-13 51.0 0.0 1.9e-13 50.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 AIN98072.1 - 8.2e-09 35.5 0.0 1.7e-08 34.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 AIN98072.1 - 1.1e-07 32.4 0.0 2.7e-07 31.1 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 AIN98072.1 - 3e-07 29.9 0.0 6.4e-07 28.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.1 AIN98072.1 - 7.8e-07 29.3 0.0 1.7e-06 28.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.10 AIN98072.1 - 2.9e-06 26.7 0.0 5.1e-06 25.9 0.0 1.3 1 0 0 1 1 1 1 Conserved hypothetical protein 95 PCMT PF01135.14 AIN98072.1 - 1.5e-05 24.6 0.0 3e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Ubie_methyltran PF01209.13 AIN98072.1 - 6.8e-05 22.0 0.0 0.00015 20.9 0.0 1.5 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_11 PF08241.7 AIN98072.1 - 0.00022 21.6 0.0 0.00098 19.5 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_15 PF09445.5 AIN98072.1 - 0.00057 19.4 0.0 0.001 18.6 0.0 1.3 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltransf_4 PF02390.12 AIN98072.1 - 0.0077 15.2 0.0 0.014 14.4 0.0 1.4 1 0 0 1 1 1 1 Putative methyltransferase PrmA PF06325.8 AIN98072.1 - 0.013 14.6 0.1 0.024 13.7 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) TPMT PF05724.6 AIN98072.1 - 0.015 14.7 0.0 0.12 11.7 0.0 2.0 2 0 0 2 2 2 0 Thiopurine S-methyltransferase (TPMT) DOT1 PF08123.8 AIN98072.1 - 0.017 14.4 0.0 0.035 13.3 0.0 1.4 1 0 0 1 1 1 0 Histone methylation protein DOT1 Methyltransf_32 PF13679.1 AIN98072.1 - 0.021 14.5 0.0 0.045 13.4 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain UPF0020 PF01170.13 AIN98072.1 - 0.026 14.1 0.0 0.051 13.1 0.0 1.5 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 DUF4580 PF15162.1 AIN98072.1 - 0.041 13.2 0.0 0.69 9.2 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4580) RNA_ligase PF09414.5 AIN98074.1 - 6.6e-51 172.7 0.0 6.6e-50 169.4 0.0 2.0 2 0 0 2 2 2 1 RNA ligase OST-HTH PF12872.2 AIN98075.1 - 0.054 13.3 0.0 0.12 12.2 0.0 1.5 1 0 0 1 1 1 0 OST-HTH/LOTUS domain Peptidase_M20 PF01546.23 AIN98076.1 - 2.2e-25 89.2 0.1 2.9e-25 88.8 0.1 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 AIN98076.1 - 4e-10 39.4 0.0 1e-09 38.1 0.0 1.7 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.12 AIN98076.1 - 0.1 12.3 0.0 0.18 11.5 0.0 1.3 1 0 0 1 1 1 0 Peptidase family M28 Peptidase_M20 PF01546.23 AIN98077.1 - 1.5e-28 99.6 0.3 1.8e-28 99.3 0.2 1.1 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 AIN98077.1 - 5.4e-10 38.9 0.0 1.3e-09 37.7 0.0 1.6 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.12 AIN98077.1 - 0.02 14.6 0.0 0.033 13.9 0.0 1.3 1 0 0 1 1 1 0 Peptidase family M28 PPR_2 PF13041.1 AIN98078.1 - 3.2e-16 59.0 4.7 2.9e-05 23.9 0.0 6.0 6 0 0 6 6 6 3 PPR repeat family PPR_3 PF13812.1 AIN98078.1 - 2.9e-14 52.0 10.4 0.0089 16.2 0.0 8.1 8 0 0 8 8 8 3 Pentatricopeptide repeat domain PPR PF01535.15 AIN98078.1 - 4e-05 23.3 5.9 0.17 11.9 0.1 5.5 6 0 0 6 6 6 2 PPR repeat PPR_1 PF12854.2 AIN98078.1 - 0.00015 21.1 0.0 0.67 9.4 0.0 4.7 5 0 0 5 5 5 1 PPR repeat Pkr1 PF08636.5 AIN98079.1 - 0.017 15.1 7.0 0.023 14.7 4.9 1.1 1 0 0 1 1 1 0 ER protein Pkr1 CHORD PF04968.7 AIN98082.1 - 1.3e-43 147.0 38.6 1.5e-23 82.7 8.6 2.6 3 0 0 3 3 3 2 CHORD Methyltransf_12 PF08242.7 AIN98083.1 - 1.6e-15 57.4 0.0 2.2e-14 53.6 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 AIN98083.1 - 1.5e-14 54.0 0.0 2.2e-14 53.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 AIN98083.1 - 1.2e-13 51.3 0.2 8.2e-11 42.2 0.0 3.3 3 1 0 3 3 3 1 Methyltransferase domain Methyltransf_31 PF13847.1 AIN98083.1 - 2.8e-11 43.2 0.0 0.00018 21.1 0.0 2.3 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_18 PF12847.2 AIN98083.1 - 1.6e-10 41.5 0.0 6.6e-10 39.5 0.0 2.0 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 AIN98083.1 - 8.1e-06 25.8 0.0 1.7e-05 24.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 AIN98083.1 - 1.9e-05 24.9 0.1 0.00011 22.4 0.0 2.3 2 1 0 2 2 2 1 Methyltransferase domain NodS PF05401.6 AIN98083.1 - 0.0035 16.7 0.1 0.0077 15.6 0.0 1.6 2 0 0 2 2 2 1 Nodulation protein S (NodS) DUF3419 PF11899.3 AIN98083.1 - 0.015 13.9 0.0 0.027 13.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3419) Ubie_methyltran PF01209.13 AIN98083.1 - 0.031 13.4 0.0 0.23 10.5 0.0 2.1 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_24 PF13578.1 AIN98083.1 - 0.041 14.7 0.0 0.12 13.1 0.0 1.9 1 1 0 1 1 1 0 Methyltransferase domain zf-rbx1 PF12678.2 AIN98084.1 - 2.5e-34 117.2 15.1 3.1e-34 116.9 10.5 1.1 1 0 0 1 1 1 1 RING-H2 zinc finger zf-Apc11 PF12861.2 AIN98084.1 - 2.2e-17 62.6 11.4 2.6e-17 62.4 7.9 1.1 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_2 PF13639.1 AIN98084.1 - 3.2e-07 30.0 15.7 4.9e-06 26.2 10.8 2.2 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 AIN98084.1 - 0.00087 18.9 14.1 0.0072 15.9 5.5 2.5 1 1 1 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 AIN98084.1 - 0.0099 15.5 15.5 0.062 12.9 9.7 2.5 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 AIN98084.1 - 0.064 13.2 15.1 1.2 9.1 10.5 2.3 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 AIN98084.1 - 0.38 10.5 14.1 6.3 6.6 9.8 2.4 1 1 1 2 2 2 0 zinc-RING finger domain Bacteriocin_II PF01721.13 AIN98084.1 - 0.39 10.2 2.4 0.74 9.3 1.6 1.5 1 0 0 1 1 1 0 Class II bacteriocin zf-HC5HC2H PF13771.1 AIN98084.1 - 0.98 9.6 12.7 1e+02 3.1 8.8 2.2 1 1 0 1 1 1 0 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.1 AIN98084.1 - 1.7 8.6 12.8 6.2 6.8 8.9 1.9 1 1 0 1 1 1 0 PHD-zinc-finger like domain zf-RING_UBOX PF13445.1 AIN98084.1 - 2.5 7.8 8.6 47 3.8 6.0 2.3 1 1 0 1 1 1 0 RING-type zinc-finger FANCL_C PF11793.3 AIN98084.1 - 3.2 7.7 12.8 24 5.0 8.9 2.2 1 1 0 1 1 1 0 FANCL C-terminal domain zf-RING-like PF08746.6 AIN98084.1 - 4.7 7.2 13.7 29 4.7 9.5 2.2 1 1 0 1 1 1 0 RING-like domain DUF2422 PF10337.4 AIN98086.1 - 0.033 13.0 2.1 0.045 12.5 1.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2422) DUF1675 PF07897.6 AIN98086.1 - 0.082 12.7 2.6 0.1 12.4 1.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) Tup_N PF08581.5 AIN98086.1 - 0.15 12.2 4.8 10 6.3 0.0 3.4 2 1 0 3 3 3 0 Tup N-terminal ALIX_LYPXL_bnd PF13949.1 AIN98087.1 - 9.3e-08 31.3 0.4 2.3e-07 30.0 0.2 1.7 1 1 0 1 1 1 1 ALIX V-shaped domain binding to HIV BAR PF03114.13 AIN98087.1 - 0.00067 19.2 8.6 0.0012 18.3 6.0 1.5 1 1 0 1 1 1 1 BAR domain Orthopox_A5L PF06193.6 AIN98087.1 - 0.0016 18.4 2.6 0.0021 17.9 1.0 1.8 2 0 0 2 2 2 1 Orthopoxvirus A5L protein-like Vps5 PF09325.5 AIN98087.1 - 0.0027 16.9 3.2 0.0044 16.3 1.9 1.5 1 1 0 1 1 1 1 Vps5 C terminal like DUF948 PF06103.6 AIN98087.1 - 0.012 15.4 0.1 3.7 7.4 0.0 3.1 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) Phasin PF05597.6 AIN98087.1 - 0.056 13.2 1.9 9 6.0 0.1 2.9 2 1 0 2 2 2 0 Poly(hydroxyalcanoate) granule associated protein (phasin) Phi-29_GP4 PF05464.6 AIN98087.1 - 0.074 12.9 0.7 0.13 12.1 0.5 1.4 1 0 0 1 1 1 0 Phi-29-like late genes activator (early protein GP4) Seryl_tRNA_N PF02403.17 AIN98087.1 - 0.13 12.3 6.1 2.3 8.2 1.5 2.6 2 1 1 3 3 3 0 Seryl-tRNA synthetase N-terminal domain She9_MDM33 PF05546.6 AIN98087.1 - 0.19 11.2 4.0 0.14 11.7 0.4 2.2 2 1 0 2 2 2 0 She9 / Mdm33 family OmpH PF03938.9 AIN98087.1 - 0.28 11.1 4.9 0.13 12.1 0.8 2.0 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) Ead_Ea22 PF13935.1 AIN98087.1 - 0.86 9.9 5.5 0.77 10.0 2.7 1.8 1 1 1 2 2 2 0 Ead/Ea22-like protein Mnd1 PF03962.10 AIN98087.1 - 0.91 9.1 6.3 0.69 9.5 2.0 2.1 2 0 0 2 2 2 0 Mnd1 family TPR_MLP1_2 PF07926.7 AIN98087.1 - 1.3 8.8 8.8 5.2 6.8 4.3 2.6 2 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein SNARE PF05739.14 AIN98088.1 - 7.3e-07 28.7 1.9 7.3e-07 28.7 1.3 2.7 3 0 0 3 3 3 1 SNARE domain Syntaxin-6_N PF09177.6 AIN98088.1 - 0.0055 17.0 4.6 0.0071 16.7 0.4 2.2 2 0 0 2 2 2 1 Syntaxin 6, N-terminal TrpBP PF02081.10 AIN98088.1 - 0.0075 15.6 0.0 0.014 14.7 0.0 1.4 1 0 0 1 1 1 1 Tryptophan RNA-binding attenuator protein DUF745 PF05335.8 AIN98088.1 - 6.5 6.2 9.0 38 3.7 0.2 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF745) WD40 PF00400.27 AIN98090.1 - 8.4e-32 107.8 7.7 2e-12 46.4 0.0 5.9 6 0 0 6 6 6 4 WD domain, G-beta repeat Nup160 PF11715.3 AIN98090.1 - 5e-05 21.6 1.8 0.076 11.1 0.1 3.4 2 1 1 3 3 3 3 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 AIN98090.1 - 0.018 13.7 0.0 22 3.6 0.0 3.4 2 2 2 4 4 4 0 Nup133 N terminal like MFS_1 PF07690.11 AIN98092.1 - 1.1e-20 73.6 29.6 1.1e-20 73.6 20.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 AIN98092.1 - 0.23 9.9 27.8 0.063 11.8 6.3 2.3 2 0 0 2 2 2 0 Sugar (and other) transporter DUF3938 PF13074.1 AIN98092.1 - 2.6 7.9 9.5 0.64 9.9 0.0 3.6 3 1 1 4 4 4 0 Protein of unknown function (DUF3938) DUF441 PF04284.8 AIN98093.1 - 0.15 11.9 3.1 3.2 7.6 0.3 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF441) UPF0542 PF15086.1 AIN98093.1 - 0.41 10.3 2.2 0.52 10.0 0.4 1.9 2 0 0 2 2 2 0 Uncharacterised protein family UPF0542 Sigma_reg_N PF13800.1 AIN98093.1 - 0.41 10.7 0.1 0.41 10.7 0.1 2.5 2 1 1 3 3 3 0 Sigma factor regulator N-terminal Calpain_III PF01067.17 AIN98096.1 - 7e-58 194.4 0.1 4.8e-24 84.6 0.0 7.9 7 2 0 7 7 7 6 Calpain large subunit, domain III Peptidase_C2 PF00648.16 AIN98096.1 - 1.1e-31 109.9 0.0 1.8e-31 109.2 0.0 1.4 1 0 0 1 1 1 1 Calpain family cysteine protease Topoisom_bac PF01131.15 AIN98097.1 - 2.4e-79 267.0 0.0 5.4e-79 265.8 0.0 1.5 1 1 0 1 1 1 1 DNA topoisomerase Toprim PF01751.17 AIN98097.1 - 2.3e-12 46.7 0.0 6.8e-12 45.2 0.0 1.9 1 0 0 1 1 1 1 Toprim domain Toprim_4 PF13662.1 AIN98097.1 - 0.0075 16.2 0.0 0.03 14.3 0.0 2.0 2 0 0 2 2 2 1 Toprim domain Sec3_C PF09763.4 AIN98097.1 - 0.03 12.4 0.0 0.16 10.0 0.0 1.8 2 0 0 2 2 2 0 Exocyst complex component Sec3 FleQ PF06490.6 AIN98097.1 - 0.031 14.4 0.0 0.068 13.3 0.0 1.6 1 0 0 1 1 1 0 Flagellar regulatory protein FleQ FliD_C PF07195.7 AIN98097.1 - 0.055 12.7 0.1 0.1 11.8 0.1 1.4 1 0 0 1 1 1 0 Flagellar hook-associated protein 2 C-terminus Pkinase PF00069.20 AIN98098.1 - 9.3e-54 182.2 0.0 1.6e-53 181.4 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AIN98098.1 - 1.7e-30 106.0 0.0 2.9e-30 105.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 AIN98098.1 - 0.00012 21.1 0.0 0.00058 18.9 0.0 2.1 2 0 0 2 2 2 1 Kinase-like Guanylate_cyc PF00211.15 AIN98098.1 - 0.0048 16.2 0.0 0.011 15.0 0.0 1.5 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain NPBW PF15180.1 AIN98098.1 - 0.019 14.6 0.1 0.051 13.2 0.1 1.7 1 0 0 1 1 1 0 Neuropeptides B and W gpUL132 PF11359.3 AIN98098.1 - 0.079 12.2 4.5 3.4 6.9 0.1 2.5 2 0 0 2 2 2 0 Glycoprotein UL132 Kdo PF06293.9 AIN98098.1 - 0.1 11.6 0.0 0.2 10.7 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family SH PF01445.12 AIN98098.1 - 2 8.1 9.7 0.7 9.5 4.3 2.1 2 0 0 2 2 2 0 Viral small hydrophobic protein Pkinase PF00069.20 AIN98100.1 - 3.6e-40 137.7 0.0 4.6e-40 137.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AIN98100.1 - 1.8e-13 50.1 0.0 8.7e-13 47.9 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 AIN98100.1 - 0.00042 19.3 0.0 0.0014 17.6 0.0 1.8 1 1 0 1 1 1 1 Kinase-like LRR_6 PF13516.1 AIN98101.1 - 5.8e-16 56.7 9.8 0.037 14.0 0.1 10.6 12 0 0 12 12 12 5 Leucine Rich repeat LRR_8 PF13855.1 AIN98101.1 - 6.2e-15 54.7 9.4 0.00058 19.5 0.0 7.1 5 2 1 6 6 6 6 Leucine rich repeat LRR_4 PF12799.2 AIN98101.1 - 1.6e-11 43.5 10.6 0.01 15.4 0.0 7.5 6 2 4 10 10 10 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 AIN98101.1 - 6.5e-08 31.5 12.3 16 6.0 0.0 10.4 12 0 0 12 12 12 1 Leucine Rich Repeat LRR_7 PF13504.1 AIN98101.1 - 0.00052 19.7 22.1 7.4 7.2 0.0 10.5 12 0 0 12 12 12 2 Leucine rich repeat Neurensin PF14927.1 AIN98101.1 - 0.11 11.9 0.5 0.25 10.7 0.0 1.8 2 0 0 2 2 2 0 Neurensin PUF PF00806.14 AIN98102.1 - 0.0048 16.3 3.3 6.5 6.4 0.0 5.7 6 1 1 7 7 7 1 Pumilio-family RNA binding repeat CHAT PF12770.2 AIN98103.1 - 1.8e-50 171.6 0.2 1.8e-50 171.6 0.2 1.8 2 0 0 2 2 2 1 CHAT domain LRR_6 PF13516.1 AIN98103.1 - 0.0007 19.4 5.7 1 9.6 0.1 3.9 2 1 1 3 3 3 2 Leucine Rich repeat LRR_4 PF12799.2 AIN98103.1 - 0.37 10.4 1.2 26 4.5 0.0 2.7 2 0 0 2 2 2 0 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 AIN98103.1 - 0.44 10.7 1.8 19 5.8 0.2 3.0 2 0 0 2 2 2 0 Leucine Rich Repeat TPR_12 PF13424.1 AIN98103.1 - 2.9 7.8 19.6 0.07 13.0 3.2 4.2 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_11 PF13414.1 AIN98103.1 - 7.7 6.2 14.5 7 6.3 0.3 4.4 4 1 1 5 5 5 0 TPR repeat MVP_shoulder PF11978.3 AIN98105.1 - 3.6e-45 152.6 0.0 6e-45 151.9 0.0 1.4 1 0 0 1 1 1 1 Shoulder domain Vault PF01505.13 AIN98105.1 - 2.8e-29 100.8 5.1 5.2e-11 42.4 0.1 5.4 5 0 0 5 5 5 3 Major Vault Protein repeat TRAPPC-Trs85 PF12739.2 AIN98106.1 - 0.048 12.3 0.7 0.072 11.7 0.5 1.2 1 0 0 1 1 1 0 ER-Golgi trafficking TRAPP I complex 85 kDa subunit EF-hand_7 PF13499.1 AIN98107.1 - 2.4e-15 56.3 0.5 7.7e-08 32.3 0.3 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 AIN98107.1 - 7.6e-09 34.7 0.4 0.004 16.9 0.0 2.7 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.27 AIN98107.1 - 7.9e-07 27.9 0.0 0.037 13.3 0.0 2.8 2 0 0 2 2 2 2 EF hand EF-hand_9 PF14658.1 AIN98107.1 - 7.7e-06 25.7 0.4 0.00018 21.3 0.0 2.7 2 1 1 3 3 3 1 EF-hand domain EF-hand_8 PF13833.1 AIN98107.1 - 1.5e-05 24.5 0.3 0.0059 16.1 0.1 3.0 1 1 2 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.1 AIN98107.1 - 0.092 12.1 0.0 8.6 5.9 0.0 2.7 2 0 0 2 2 2 0 EF hand EFhand_Ca_insen PF08726.5 AIN98107.1 - 0.13 12.2 0.0 0.31 11.0 0.0 1.8 1 1 0 1 1 1 0 Ca2+ insensitive EF hand EF-hand_like PF09279.6 AIN98107.1 - 0.14 12.2 0.1 0.43 10.6 0.0 1.8 2 0 0 2 2 2 0 Phosphoinositide-specific phospholipase C, efhand-like DUF384 PF04064.8 AIN98107.1 - 0.32 10.6 2.2 0.76 9.3 0.8 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF384) Actin PF00022.14 AIN98108.1 - 4.2e-36 124.2 0.0 6.6e-36 123.5 0.0 1.3 1 0 0 1 1 1 1 Actin Hexokinase_1 PF00349.16 AIN98109.1 - 1.2e-62 210.8 0.0 1.8e-62 210.3 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Hexokinase_2 PF03727.11 AIN98109.1 - 6.2e-53 179.4 0.1 1.7e-52 178.0 0.0 1.7 2 0 0 2 2 2 1 Hexokinase PPR_3 PF13812.1 AIN98110.1 - 6.9e-14 50.8 7.9 0.2 12.0 0.0 8.4 9 1 0 9 9 9 4 Pentatricopeptide repeat domain PPR_2 PF13041.1 AIN98110.1 - 1.6e-12 47.1 0.1 0.0093 15.9 0.0 4.6 4 0 0 4 4 4 3 PPR repeat family PPR_1 PF12854.2 AIN98110.1 - 0.00051 19.4 0.0 0.096 12.1 0.0 3.3 2 0 0 2 2 2 1 PPR repeat PPR PF01535.15 AIN98110.1 - 0.00067 19.4 2.8 29 4.9 0.1 6.6 7 0 0 7 7 7 0 PPR repeat ECSIT PF06239.6 AIN98110.1 - 0.0086 14.9 0.1 0.031 13.1 0.0 2.0 3 0 0 3 3 3 1 Evolutionarily conserved signalling intermediate in Toll pathway TPR_8 PF13181.1 AIN98110.1 - 0.06 13.1 0.0 0.59 10.0 0.0 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat Pkinase PF00069.20 AIN98111.1 - 1.5e-44 152.0 0.0 5.8e-43 146.9 0.0 2.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AIN98111.1 - 1.1e-29 103.2 0.5 2.2e-21 76.0 0.1 3.0 3 0 0 3 3 3 2 Protein tyrosine kinase RIO1 PF01163.17 AIN98111.1 - 0.0017 17.7 0.3 0.0034 16.7 0.2 1.5 1 0 0 1 1 1 1 RIO1 family DUF3082 PF11282.3 AIN98112.1 - 0.057 13.4 0.1 0.18 11.8 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3082) DeoC PF01791.4 AIN98112.1 - 0.078 12.2 0.0 0.14 11.4 0.0 1.3 1 0 0 1 1 1 0 DeoC/LacD family aldolase LRR_4 PF12799.2 AIN98113.1 - 0.0092 15.5 0.1 0.25 11.0 0.0 2.4 2 0 0 2 2 2 1 Leucine Rich repeats (2 copies) zf-U1 PF06220.7 AIN98116.1 - 0.00021 20.7 4.8 0.00021 20.7 3.3 2.0 2 0 0 2 2 2 1 U1 zinc finger zf-C2H2_jaz PF12171.3 AIN98116.1 - 0.0039 17.2 1.0 0.0096 16.0 0.7 1.7 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding AKAP95 PF04988.7 AIN98116.1 - 0.0079 15.9 0.5 0.012 15.4 0.4 1.2 1 0 0 1 1 1 1 A-kinase anchoring protein 95 (AKAP95) zf-C2H2_4 PF13894.1 AIN98116.1 - 0.49 10.8 2.5 5.2 7.6 1.7 2.5 1 1 0 1 1 1 0 C2H2-type zinc finger Vps51 PF08700.6 AIN98117.1 - 1.1e-24 86.0 1.8 3.3e-24 84.5 1.2 1.9 1 0 0 1 1 1 1 Vps51/Vps67 Sec5 PF15469.1 AIN98117.1 - 1.5e-10 41.1 0.3 1.3e-09 38.0 0.2 2.2 2 1 0 2 2 2 1 Exocyst complex component Sec5 Dor1 PF04124.7 AIN98117.1 - 3.9e-07 28.8 3.2 6.8e-07 28.0 2.2 1.3 1 0 0 1 1 1 1 Dor1-like family Vps53_N PF04100.7 AIN98117.1 - 1.3e-06 27.4 1.1 2.4e-06 26.6 0.8 1.3 1 0 0 1 1 1 1 Vps53-like, N-terminal DUF2450 PF10475.4 AIN98117.1 - 1.4e-06 27.3 3.4 2.6e-06 26.5 2.3 1.3 1 0 0 1 1 1 1 Protein of unknown function N-terminal domain (DUF2450) COG2 PF06148.6 AIN98117.1 - 5.2e-06 26.3 4.1 3.4e-05 23.7 1.1 3.1 3 1 0 3 3 3 1 COG (conserved oligomeric Golgi) complex component, COG2 Transposase_22 PF02994.9 AIN98117.1 - 0.0029 16.1 0.9 0.0046 15.5 0.6 1.2 1 0 0 1 1 1 1 L1 transposable element COG5 PF10392.4 AIN98117.1 - 0.034 14.1 3.3 0.069 13.1 1.5 2.1 2 0 0 2 2 2 0 Golgi transport complex subunit 5 CENP-F_leu_zip PF10473.4 AIN98117.1 - 0.22 11.3 5.5 0.091 12.6 1.9 1.7 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Peptidase_M16 PF00675.15 AIN98118.1 - 2.6e-12 46.7 0.0 5.7e-12 45.6 0.0 1.6 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 AIN98118.1 - 1.8e-05 24.4 0.0 0.00014 21.6 0.0 2.4 2 1 0 2 2 2 1 Peptidase M16 inactive domain DUF607 PF04678.8 AIN98119.1 - 1.3e-33 116.3 1.7 1.6e-33 116.1 1.2 1.2 1 0 0 1 1 1 1 Protein of unknown function, DUF607 DUF1843 PF08898.5 AIN98119.1 - 0.38 10.8 2.7 12 6.0 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1843) CCDC92 PF14916.1 AIN98120.1 - 0.027 14.0 0.1 0.066 12.8 0.1 1.6 1 0 0 1 1 1 0 Coiled-coil domain of unknown function RPAP2_Rtr1 PF04181.8 AIN98121.1 - 7e-09 35.6 0.0 1.1e-05 25.4 0.0 2.3 2 0 0 2 2 2 2 Rtr1/RPAP2 family DUF667 PF05018.8 AIN98122.1 - 4.2e-102 339.2 0.5 4.8e-102 339.0 0.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF667) PDDEXK_1 PF12705.2 AIN98123.1 - 9.5e-05 21.8 0.0 0.00012 21.5 0.0 1.3 1 0 0 1 1 1 1 PD-(D/E)XK nuclease superfamily UCH PF00443.24 AIN98124.1 - 1.9e-50 171.5 0.4 2.7e-50 170.9 0.3 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 AIN98124.1 - 4.9e-20 72.1 0.9 1.5e-19 70.5 0.6 1.8 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Alpha-2-MRAP_N PF06400.6 AIN98124.1 - 0.0029 17.2 0.8 0.0059 16.2 0.5 1.4 1 0 0 1 1 1 1 Alpha-2-macroglobulin RAP, N-terminal domain DUF325 PF03804.8 AIN98124.1 - 0.11 12.2 0.1 0.29 10.8 0.1 1.6 1 0 0 1 1 1 0 Viral domain of unknown function Piwi PF02171.12 AIN98125.1 - 1.9e-08 33.6 0.0 2.7e-08 33.1 0.0 1.2 1 0 0 1 1 1 1 Piwi domain Pyr_redox_2 PF07992.9 AIN98126.1 - 3.7e-06 26.9 0.0 3.4e-05 23.8 0.0 2.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 AIN98126.1 - 9.7e-06 25.5 0.0 4.5e-05 23.3 0.0 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 AIN98126.1 - 0.00026 21.1 0.0 0.029 14.4 0.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 AIN98126.1 - 0.00071 19.3 0.0 0.0022 17.7 0.0 1.9 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox PF00070.22 AIN98126.1 - 0.00089 19.6 0.0 0.067 13.5 0.0 2.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 AIN98126.1 - 0.0095 14.8 0.0 0.032 13.1 0.0 2.1 2 1 0 2 2 2 1 FAD dependent oxidoreductase MRP-S31 PF15433.1 AIN98127.1 - 0.0093 15.4 6.3 0.014 14.8 4.4 1.2 1 0 0 1 1 1 1 Mitochondrial 28S ribosomal protein S31 Kua-UEV1_localn PF10520.4 AIN98128.1 - 5.6e-69 231.3 1.3 7.2e-69 231.0 0.9 1.1 1 0 0 1 1 1 1 Kua-ubiquitin conjugating enzyme hybrid localisation domain DUF2208 PF09973.4 AIN98128.1 - 0.036 13.3 0.0 0.16 11.1 0.0 1.8 1 1 1 2 2 2 0 Predicted membrane protein (DUF2208) FA_hydroxylase PF04116.8 AIN98128.1 - 1.9 8.9 9.7 5.1 7.5 0.2 2.4 1 1 1 2 2 2 0 Fatty acid hydroxylase superfamily Vps35 PF03635.12 AIN98130.1 - 1.3e-237 790.7 0.0 1.5e-237 790.5 0.0 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 35 FAM124 PF15067.1 AIN98130.1 - 0.075 12.4 0.2 0.15 11.4 0.2 1.4 1 0 0 1 1 1 0 FAM124 family MAD PF05557.8 AIN98131.1 - 0.011 13.9 12.0 0.018 13.1 8.3 1.4 1 0 0 1 1 1 0 Mitotic checkpoint protein DUF444 PF04285.7 AIN98131.1 - 0.036 12.6 0.9 0.053 12.1 0.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF444) CALCOCO1 PF07888.6 AIN98131.1 - 0.36 9.0 22.7 0.013 13.8 10.6 2.1 2 1 1 3 3 3 0 Calcium binding and coiled-coil domain (CALCOCO1) like GAS PF13851.1 AIN98131.1 - 0.79 8.8 8.6 0.074 12.2 0.7 2.7 1 1 2 3 3 3 0 Growth-arrest specific micro-tubule binding DUF972 PF06156.8 AIN98131.1 - 1.5 9.2 7.2 1.9 8.9 0.5 3.7 4 0 0 4 4 4 0 Protein of unknown function (DUF972) DUF3613 PF12266.3 AIN98131.1 - 1.7 8.1 8.6 4.5 6.8 2.1 3.1 2 1 0 2 2 2 0 Protein of unknown function (DUF3613) FTA4 PF13093.1 AIN98131.1 - 2.4 7.5 6.8 0.75 9.1 2.5 1.8 2 0 0 2 2 2 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 Tropomyosin PF00261.15 AIN98131.1 - 2.6 7.0 24.3 0.97 8.4 0.1 3.7 2 1 1 3 3 3 0 Tropomyosin DnaJ PF00226.26 AIN98132.1 - 3.5e-26 90.7 1.5 5.8e-26 90.0 1.1 1.4 1 0 0 1 1 1 1 DnaJ domain CTDII PF01556.13 AIN98132.1 - 2.5e-18 65.7 0.0 2.3e-14 53.0 0.0 3.3 3 0 0 3 3 3 2 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.14 AIN98132.1 - 1.4e-13 50.6 14.5 2.6e-13 49.8 10.1 1.5 1 0 0 1 1 1 1 DnaJ central domain DUF3268 PF11672.3 AIN98132.1 - 0.17 12.0 1.5 0.35 10.9 1.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3268) HypA PF01155.14 AIN98132.1 - 5.9 6.6 7.4 1.8 8.2 1.2 2.3 1 1 0 2 2 2 0 Hydrogenase expression/synthesis hypA family Methyltransf_13 PF08421.6 AIN98133.1 - 0.098 12.1 0.2 0.89 9.0 0.0 2.1 2 0 0 2 2 2 0 Putative zinc binding domain CH PF00307.26 AIN98133.1 - 0.13 12.2 0.1 0.25 11.3 0.0 1.4 1 1 0 1 1 1 0 Calponin homology (CH) domain PQQ_3 PF13570.1 AIN98135.1 - 0.012 15.8 0.5 0.21 11.9 0.2 3.1 2 0 0 2 2 2 0 PQQ-like domain TPR_11 PF13414.1 AIN98136.1 - 5.2e-18 64.4 13.9 1.2e-05 24.8 0.0 6.0 3 1 1 5 5 5 5 TPR repeat TPR_14 PF13428.1 AIN98136.1 - 1.2e-17 62.7 37.5 0.009 16.5 0.2 10.2 5 3 4 9 9 9 7 Tetratricopeptide repeat TPR_19 PF14559.1 AIN98136.1 - 2e-13 50.4 18.3 0.00011 22.5 0.0 6.5 5 2 2 7 7 7 4 Tetratricopeptide repeat TPR_16 PF13432.1 AIN98136.1 - 9.7e-13 48.4 36.5 4.8e-05 23.8 0.1 7.9 7 2 0 7 7 6 4 Tetratricopeptide repeat TPR_2 PF07719.12 AIN98136.1 - 2e-12 45.9 21.5 0.008 16.0 0.1 8.4 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_1 PF00515.23 AIN98136.1 - 1.1e-11 43.7 10.2 0.019 14.5 0.1 6.5 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_12 PF13424.1 AIN98136.1 - 7.4e-11 41.8 18.4 0.01 15.7 0.2 5.6 4 2 1 5 5 5 4 Tetratricopeptide repeat Apc3 PF12895.2 AIN98136.1 - 4e-08 33.2 5.6 0.0088 16.1 0.5 4.4 4 1 0 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.1 AIN98136.1 - 1.9e-07 30.3 1.5 9.2 6.3 0.0 5.8 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_7 PF13176.1 AIN98136.1 - 3.6e-06 26.3 11.7 3.4 7.7 0.1 6.6 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_10 PF13374.1 AIN98136.1 - 0.011 15.6 19.9 0.034 14.0 0.1 6.7 7 0 0 7 7 6 0 Tetratricopeptide repeat TPR_17 PF13431.1 AIN98136.1 - 0.014 15.5 11.8 36 4.9 0.1 6.6 8 0 0 8 8 7 0 Tetratricopeptide repeat TPR_9 PF13371.1 AIN98136.1 - 0.023 14.5 24.6 0.052 13.4 0.2 5.9 6 0 0 6 6 5 0 Tetratricopeptide repeat TPR_6 PF13174.1 AIN98136.1 - 0.54 10.8 18.8 4.4 7.9 0.1 5.9 7 0 0 7 7 6 0 Tetratricopeptide repeat La PF05383.12 AIN98137.1 - 1.2e-21 76.2 0.0 6e-21 74.0 0.0 2.1 2 0 0 2 2 2 1 La domain RRM_1 PF00076.17 AIN98137.1 - 1.2e-06 28.0 0.2 0.00013 21.5 0.1 3.2 2 1 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 AIN98137.1 - 6.9e-06 25.9 0.0 0.0031 17.4 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 AIN98137.1 - 0.0036 17.1 0.1 1.7 8.5 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 AIN98137.1 - 0.0084 15.9 2.2 0.13 12.1 0.2 2.9 2 1 0 2 2 2 1 RNA binding motif API5 PF05918.6 AIN98137.1 - 0.063 11.7 1.4 0.089 11.2 0.3 1.7 2 0 0 2 2 2 0 Apoptosis inhibitory protein 5 (API5) Biotin_lipoyl PF00364.17 AIN98138.1 - 1.1e-14 53.7 0.1 2.1e-14 52.9 0.1 1.5 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.12 AIN98138.1 - 0.012 15.2 0.7 0.067 12.8 0.0 2.6 3 0 0 3 3 3 0 e3 binding domain SNARE PF05739.14 AIN98139.1 - 7.8e-08 31.8 6.2 9.4e-08 31.6 4.3 1.1 1 0 0 1 1 1 1 SNARE domain V-SNARE_C PF12352.3 AIN98139.1 - 0.027 14.5 0.9 0.053 13.6 0.6 1.6 1 1 0 1 1 1 0 Snare region anchored in the vesicle membrane C-terminus ExoD PF06055.7 AIN98139.1 - 0.059 12.4 0.5 0.084 11.9 0.1 1.4 2 0 0 2 2 2 0 Exopolysaccharide synthesis, ExoD ocr PF08684.5 AIN98139.1 - 0.065 13.2 1.0 1.3 9.0 0.0 2.1 1 1 1 2 2 2 0 DNA mimic ocr Exc PF07825.6 AIN98140.1 - 0.012 15.3 1.1 0.33 10.7 0.0 2.8 2 0 0 2 2 2 0 Excisionase-like protein TPR_MLP1_2 PF07926.7 AIN98140.1 - 0.12 12.1 0.8 0.29 10.8 0.5 1.6 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein INTS5_N PF14837.1 AIN98141.1 - 0.033 13.5 0.4 0.9 8.9 0.0 2.4 2 0 0 2 2 2 0 Integrator complex subunit 5 N-terminus BssS PF13991.1 AIN98141.1 - 0.081 12.6 0.0 0.26 11.0 0.0 1.8 1 0 0 1 1 1 0 BssS protein family Smr PF01713.16 AIN98141.1 - 0.099 12.8 0.0 6.1 7.1 0.0 2.9 2 0 0 2 2 2 0 Smr domain DAGK_prokar PF01219.14 AIN98141.1 - 0.22 11.1 0.1 0.22 11.1 0.1 2.1 2 0 0 2 2 2 0 Prokaryotic diacylglycerol kinase Noelin-1 PF12308.3 AIN98142.1 - 0.052 13.3 0.1 0.14 12.0 0.0 1.6 1 0 0 1 1 1 0 Neurogenesis glycoprotein DEAD PF00270.24 AIN98144.1 - 1e-15 57.6 0.0 5.7e-12 45.4 0.0 2.5 2 0 0 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.26 AIN98144.1 - 5.7e-14 51.7 0.0 1.4e-13 50.4 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 AIN98144.1 - 0.013 15.3 0.0 0.039 13.7 0.0 1.8 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit SecA_DEAD PF07517.9 AIN98144.1 - 0.053 12.7 0.3 0.12 11.6 0.0 1.6 2 0 0 2 2 2 0 SecA DEAD-like domain IMS_C PF11799.3 AIN98145.1 - 0.071 13.0 0.0 0.12 12.2 0.0 1.3 1 0 0 1 1 1 0 impB/mucB/samB family C-terminal domain DsrD PF08679.6 AIN98145.1 - 0.12 12.3 0.0 0.26 11.3 0.0 1.5 1 0 0 1 1 1 0 Dissimilatory sulfite reductase D (DsrD) IMS PF00817.15 AIN98146.1 - 1.2e-13 51.1 0.0 1.2e-13 51.0 0.0 1.1 1 0 0 1 1 1 1 impB/mucB/samB family IMS PF00817.15 AIN98147.1 - 7.5e-50 168.5 0.3 1.1e-49 168.0 0.2 1.3 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.3 AIN98147.1 - 2.2e-10 40.5 0.0 4.2e-10 39.6 0.0 1.4 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.3 AIN98147.1 - 0.00093 19.1 0.0 0.0021 18.0 0.0 1.6 1 0 0 1 1 1 1 IMS family HHH motif PGM_PMM_I PF02878.11 AIN98148.1 - 7.5e-32 109.7 0.0 1.3e-31 108.8 0.0 1.4 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_III PF02880.11 AIN98148.1 - 1.3e-25 89.6 0.0 3.5e-25 88.2 0.0 1.8 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.11 AIN98148.1 - 8.8e-11 42.0 0.2 7.9e-10 39.0 0.1 2.6 1 1 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.15 AIN98148.1 - 6.4e-10 38.9 0.0 1.5e-09 37.6 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain ParA PF10609.4 AIN98150.1 - 3.6e-33 113.2 0.0 6.7e-33 112.4 0.0 1.4 1 0 0 1 1 1 1 ParA/MinD ATPase like CbiA PF01656.18 AIN98150.1 - 1.1e-16 60.8 0.0 1.5e-16 60.4 0.0 1.1 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain MipZ PF09140.6 AIN98150.1 - 1e-06 28.0 0.0 1.6e-06 27.4 0.0 1.3 1 0 0 1 1 1 1 ATPase MipZ AAA_31 PF13614.1 AIN98150.1 - 2.8e-06 27.3 0.0 9e-06 25.6 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 AIN98150.1 - 0.0017 19.1 0.0 0.0027 18.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain ArsA_ATPase PF02374.10 AIN98150.1 - 0.005 15.9 2.5 0.0057 15.7 0.7 1.7 2 0 0 2 2 2 1 Anion-transporting ATPase ArgK PF03308.11 AIN98150.1 - 0.01 14.6 0.3 0.015 14.1 0.2 1.2 1 0 0 1 1 1 0 ArgK protein AAA_16 PF13191.1 AIN98150.1 - 0.016 15.2 0.1 0.026 14.5 0.1 1.3 1 0 0 1 1 1 0 AAA ATPase domain AAA_18 PF13238.1 AIN98150.1 - 0.017 15.4 0.0 0.026 14.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain MobB PF03205.9 AIN98150.1 - 0.021 14.5 0.0 0.035 13.8 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Fer4_NifH PF00142.13 AIN98150.1 - 0.041 13.0 0.0 0.13 11.4 0.1 1.7 2 0 0 2 2 2 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family AAA_10 PF12846.2 AIN98150.1 - 0.066 12.6 0.4 0.11 11.9 0.3 1.3 1 0 0 1 1 1 0 AAA-like domain NTPase_1 PF03266.10 AIN98150.1 - 0.12 12.0 0.2 0.22 11.2 0.2 1.4 1 0 0 1 1 1 0 NTPase ATP_bind_1 PF03029.12 AIN98150.1 - 0.13 11.7 0.3 0.24 10.9 0.1 1.5 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein RNA_helicase PF00910.17 AIN98150.1 - 0.16 12.1 0.2 0.32 11.2 0.1 1.5 1 0 0 1 1 1 0 RNA helicase Lactamase_B PF00753.22 AIN98151.1 - 1.1e-22 80.5 0.2 2.4e-22 79.5 0.1 1.6 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 AIN98151.1 - 0.00016 21.2 0.0 0.0012 18.3 0.0 2.1 1 1 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 AIN98151.1 - 0.00083 19.0 0.0 0.0021 17.7 0.0 1.8 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Hist_deacetyl PF00850.14 AIN98152.1 - 7.2e-65 219.3 0.1 9.4e-65 218.9 0.0 1.1 1 0 0 1 1 1 1 Histone deacetylase domain DSPc PF00782.15 AIN98154.1 - 1.1e-18 67.0 0.0 1.6e-18 66.5 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain ABC_tran PF00005.22 AIN98155.1 - 1.1e-36 126.1 0.0 2.5e-17 63.4 0.0 2.4 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 AIN98155.1 - 6.7e-15 55.8 4.8 0.0026 17.7 0.0 4.6 4 1 1 5 5 5 3 AAA domain SMC_N PF02463.14 AIN98155.1 - 7.1e-11 41.7 2.2 0.00069 18.9 0.2 3.9 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain RLI PF04068.10 AIN98155.1 - 8.7e-09 34.8 5.7 8.7e-09 34.8 3.9 1.8 2 0 0 2 2 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI Fer4 PF00037.22 AIN98155.1 - 9.7e-08 31.3 2.2 9.7e-08 31.3 1.5 2.2 2 0 0 2 2 2 1 4Fe-4S binding domain AAA_15 PF13175.1 AIN98155.1 - 1.2e-06 27.8 0.0 0.5 9.3 0.0 3.5 4 0 0 4 4 3 2 AAA ATPase domain AAA_29 PF13555.1 AIN98155.1 - 5.3e-06 25.8 0.1 0.011 15.2 0.0 2.4 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.1 AIN98155.1 - 4.1e-05 23.7 0.4 0.0059 16.7 0.0 2.8 2 1 0 2 2 2 1 AAA domain Fer4_21 PF14697.1 AIN98155.1 - 5.4e-05 22.9 14.4 0.00012 21.8 10.0 1.6 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_6 PF12837.2 AIN98155.1 - 8.6e-05 22.2 2.1 8.6e-05 22.2 1.5 2.6 2 0 0 2 2 2 1 4Fe-4S binding domain AAA_16 PF13191.1 AIN98155.1 - 0.0001 22.3 0.0 0.017 15.0 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain Miro PF08477.8 AIN98155.1 - 0.0002 21.8 0.1 0.039 14.4 0.0 2.7 2 1 0 2 2 2 1 Miro-like protein UPF0079 PF02367.12 AIN98155.1 - 0.00024 20.7 0.0 0.0024 17.5 0.0 2.2 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 Fer4_7 PF12838.2 AIN98155.1 - 0.00037 20.8 0.3 0.00037 20.8 0.2 2.6 2 0 0 2 2 2 1 4Fe-4S dicluster domain DUF258 PF03193.11 AIN98155.1 - 0.00048 19.3 0.0 0.15 11.2 0.0 2.6 2 0 0 2 2 2 1 Protein of unknown function, DUF258 NACHT PF05729.7 AIN98155.1 - 0.00051 19.7 0.3 0.014 15.0 0.0 2.3 2 0 0 2 2 2 1 NACHT domain AAA PF00004.24 AIN98155.1 - 0.00052 20.2 0.3 0.032 14.4 0.0 2.7 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_23 PF13476.1 AIN98155.1 - 0.0006 20.1 1.5 0.11 12.8 0.1 2.4 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.1 AIN98155.1 - 0.00061 19.2 0.0 0.89 8.9 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_17 PF13207.1 AIN98155.1 - 0.00071 20.3 0.1 0.46 11.3 0.0 2.9 2 1 0 2 2 2 1 AAA domain RNA_helicase PF00910.17 AIN98155.1 - 0.0019 18.3 0.0 0.55 10.4 0.0 3.0 3 0 0 3 3 2 1 RNA helicase AAA_28 PF13521.1 AIN98155.1 - 0.002 18.1 0.0 1.9 8.4 0.0 2.7 3 0 0 3 3 2 1 AAA domain Fer4_10 PF13237.1 AIN98155.1 - 0.0032 17.2 1.6 0.0032 17.2 1.1 2.2 1 1 1 2 2 2 2 4Fe-4S dicluster domain AAA_33 PF13671.1 AIN98155.1 - 0.0035 17.2 0.1 0.69 9.7 0.0 2.7 2 0 0 2 2 2 1 AAA domain VirE PF05272.6 AIN98155.1 - 0.0045 16.4 0.0 1.2 8.5 0.0 2.6 2 0 0 2 2 2 1 Virulence-associated protein E AAA_18 PF13238.1 AIN98155.1 - 0.0057 16.9 0.1 1.4 9.2 0.0 2.9 2 1 0 2 2 2 1 AAA domain AAA_14 PF13173.1 AIN98155.1 - 0.0067 16.3 0.0 0.59 10.0 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.9 AIN98155.1 - 0.0069 16.1 1.0 0.64 9.7 0.0 2.9 3 0 0 3 3 2 1 AAA domain (dynein-related subfamily) SRP54 PF00448.17 AIN98155.1 - 0.0085 15.5 0.3 0.87 9.0 0.0 2.2 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain Fer4_2 PF12797.2 AIN98155.1 - 0.0087 15.9 2.2 0.0087 15.9 1.5 2.7 2 0 0 2 2 2 1 4Fe-4S binding domain Fer4_3 PF12798.2 AIN98155.1 - 0.014 15.9 4.7 0.014 15.9 3.2 2.6 2 0 0 2 2 1 0 4Fe-4S binding domain Rad17 PF03215.10 AIN98155.1 - 0.018 13.7 0.1 0.57 8.8 0.0 2.2 2 0 0 2 2 2 0 Rad17 cell cycle checkpoint protein AAA_30 PF13604.1 AIN98155.1 - 0.021 14.3 0.0 3.9 7.0 0.0 2.4 2 0 0 2 2 2 0 AAA domain MobB PF03205.9 AIN98155.1 - 0.022 14.4 0.2 2.2 7.9 0.0 2.4 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_19 PF13245.1 AIN98155.1 - 0.038 13.7 0.3 4.4 7.1 0.0 2.5 2 0 0 2 2 2 0 Part of AAA domain SbcCD_C PF13558.1 AIN98155.1 - 0.041 13.7 0.0 5.1 7.0 0.0 2.7 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit Fer4_9 PF13187.1 AIN98155.1 - 0.072 13.3 13.7 0.26 11.5 9.6 2.0 1 1 0 1 1 1 0 4Fe-4S dicluster domain AAA_13 PF13166.1 AIN98155.1 - 0.21 10.0 2.7 0.78 8.1 0.0 2.4 3 0 0 3 3 2 0 AAA domain PduV-EutP PF10662.4 AIN98155.1 - 0.45 9.9 1.7 1.4 8.4 0.0 2.5 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation Fer4_4 PF12800.2 AIN98155.1 - 7.1 7.2 15.9 0.068 13.5 1.7 2.6 2 0 0 2 2 1 0 4Fe-4S binding domain Hpt PF01627.18 AIN98156.1 - 0.01 15.8 0.1 0.029 14.3 0.0 1.7 1 0 0 1 1 1 0 Hpt domain Leu_Phe_trans PF03588.9 AIN98157.1 - 6.3e-07 28.6 0.0 8.2e-05 21.8 0.0 2.5 2 1 1 3 3 3 2 Leucyl/phenylalanyl-tRNA protein transferase Ribosomal_L36e PF01158.13 AIN98158.1 - 2.1e-33 114.1 2.1 2.6e-33 113.9 1.4 1.0 1 0 0 1 1 1 1 Ribosomal protein L36e DUF543 PF04418.7 AIN98159.1 - 1.3e-18 66.7 0.8 1.6e-18 66.4 0.5 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF543) DLH PF01738.13 AIN98159.1 - 0.0024 17.1 0.1 0.0024 17.1 0.1 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family ATP-synt_C PF00137.16 AIN98160.1 - 4.7e-17 61.6 12.4 7.3e-17 61.0 8.6 1.3 1 0 0 1 1 1 1 ATP synthase subunit C PCI PF01399.22 AIN98162.1 - 2.1e-13 50.5 0.9 6e-13 49.0 0.1 2.3 2 0 0 2 2 2 1 PCI domain NPV_P10 PF05531.7 AIN98162.1 - 0.27 11.5 4.3 3.1 8.0 0.1 3.6 3 1 1 4 4 4 0 Nucleopolyhedrovirus P10 protein Vps39_1 PF10366.4 AIN98162.1 - 0.49 10.4 9.1 4.1 7.4 1.7 3.3 2 1 1 3 3 3 0 Vacuolar sorting protein 39 domain 1 Ras PF00071.17 AIN98165.1 - 1.6e-45 154.3 0.0 2e-45 154.0 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 AIN98165.1 - 1.2e-19 70.9 0.0 1.7e-19 70.4 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 AIN98165.1 - 4.7e-10 38.9 0.0 8.7e-10 38.1 0.0 1.4 1 1 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 AIN98165.1 - 1.2e-06 28.0 0.0 3.3e-06 26.6 0.0 1.7 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 AIN98165.1 - 4.9e-05 22.5 0.0 6e-05 22.2 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 AIN98165.1 - 0.0011 18.9 0.0 0.0017 18.3 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_25 PF13481.1 AIN98165.1 - 0.01 15.2 0.0 1.9 7.8 0.0 2.6 2 1 0 2 2 2 0 AAA domain AAA_22 PF13401.1 AIN98165.1 - 0.16 12.0 0.0 0.55 10.3 0.0 1.8 1 1 0 1 1 1 0 AAA domain Not1 PF04054.10 AIN98166.1 - 8.6e-112 373.7 7.0 1.9e-111 372.6 4.8 1.6 1 0 0 1 1 1 1 CCR4-Not complex component, Not1 DUF3819 PF12842.2 AIN98166.1 - 5.2e-31 107.3 0.4 2.4e-30 105.1 0.2 2.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3819) tRNA-synt_1g PF09334.6 AIN98167.1 - 3.8e-110 368.2 0.1 5e-110 367.8 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.17 AIN98167.1 - 2.8e-18 65.2 1.0 4.6e-09 34.8 0.8 3.1 2 1 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1e PF01406.14 AIN98167.1 - 3.9e-07 29.4 0.1 0.0011 18.1 0.1 2.2 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain tRNA-synt_1d PF00750.14 AIN98167.1 - 0.037 12.8 0.4 0.33 9.7 0.3 2.2 2 1 1 3 3 3 0 tRNA synthetases class I (R) MKT1_N PF12247.3 AIN98168.1 - 1.7e-21 76.3 0.0 3.3e-21 75.4 0.0 1.5 1 0 0 1 1 1 1 Temperature dependent protein affecting M2 dsRNA replication MKT1_C PF12246.3 AIN98168.1 - 7.2e-15 54.6 0.0 1.2e-14 53.8 0.0 1.2 1 0 0 1 1 1 1 Temperature dependent protein affecting M2 dsRNA replication Pkinase PF00069.20 AIN98169.1 - 9e-39 133.1 0.0 2.7e-38 131.5 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AIN98169.1 - 4.7e-24 84.8 0.1 4.7e-14 52.0 0.0 3.3 3 0 0 3 3 3 3 Protein tyrosine kinase APH PF01636.18 AIN98169.1 - 0.0055 16.4 0.1 0.019 14.6 0.0 1.9 2 0 0 2 2 2 1 Phosphotransferase enzyme family RVT_2 PF07727.9 AIN98172.1 - 0.078 11.9 0.0 0.13 11.2 0.0 1.2 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) Peptidase_M24 PF00557.19 AIN98174.1 - 8e-43 146.4 0.1 1.1e-42 145.9 0.1 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 DUF4612 PF15389.1 AIN98174.1 - 0.24 12.0 4.3 20 5.8 0.0 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4612) RCR PF12273.3 AIN98175.1 - 0.91 10.0 8.4 0.51 10.8 1.5 2.6 2 1 0 2 2 2 0 Chitin synthesis regulation, resistance to Congo red Pribosyltran PF00156.22 AIN98176.1 - 4.8e-12 45.6 0.0 6.5e-12 45.2 0.0 1.2 1 0 0 1 1 1 1 Phosphoribosyl transferase domain Pribosyltran PF00156.22 AIN98177.1 - 1.4e-13 50.7 0.2 4.1e-13 49.1 0.0 1.7 2 0 0 2 2 2 1 Phosphoribosyl transferase domain Pkinase PF00069.20 AIN98178.1 - 4.9e-53 179.9 0.0 1.4e-36 126.0 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 AIN98178.1 - 1.7e-27 96.1 0.0 3.5e-18 65.6 0.0 2.7 2 1 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 AIN98178.1 - 7e-08 31.7 0.0 1.5e-07 30.7 0.0 1.4 1 0 0 1 1 1 1 Kinase-like BAG PF02179.11 AIN98179.1 - 7.8e-05 22.7 0.0 0.00014 21.8 0.0 1.3 1 0 0 1 1 1 1 BAG domain HEAT PF02985.17 AIN98183.1 - 0.007 16.3 2.6 0.12 12.5 0.0 4.0 5 0 0 5 5 5 1 HEAT repeat HEAT_EZ PF13513.1 AIN98183.1 - 0.03 14.8 4.0 0.97 10.0 0.1 3.4 2 0 0 2 2 2 0 HEAT-like repeat PUA PF01472.15 AIN98183.1 - 0.056 13.1 0.0 0.16 11.6 0.0 1.8 1 0 0 1 1 1 0 PUA domain HEAT_2 PF13646.1 AIN98183.1 - 0.47 10.7 5.7 0.46 10.8 0.5 3.1 2 1 2 4 4 4 0 HEAT repeats HEAT_2 PF13646.1 AIN98184.1 - 2.6e-09 37.2 4.3 0.0023 18.1 0.0 3.9 4 0 0 4 4 4 2 HEAT repeats DUF4042 PF13251.1 AIN98184.1 - 6e-09 35.6 0.8 3.2e-05 23.4 0.1 4.5 4 1 0 4 4 4 1 Domain of unknown function (DUF4042) HEAT PF02985.17 AIN98184.1 - 1.2e-07 31.1 0.7 0.96 9.7 0.0 6.4 5 0 0 5 5 5 2 HEAT repeat HEAT_EZ PF13513.1 AIN98184.1 - 9.5e-07 29.1 15.0 0.00021 21.6 0.3 6.8 4 2 2 6 6 6 2 HEAT-like repeat Adaptin_N PF01602.15 AIN98184.1 - 0.56 8.4 0.0 0.95 7.7 0.0 1.3 1 0 0 1 1 1 0 Adaptin N terminal region ABC2_membrane PF01061.19 AIN98185.1 - 5.9e-12 45.2 17.9 5.9e-12 45.2 12.4 1.9 2 0 0 2 2 2 1 ABC-2 type transporter ABC_tran PF00005.22 AIN98185.1 - 9.9e-09 35.6 0.0 1.7e-08 34.8 0.0 1.4 1 0 0 1 1 1 1 ABC transporter zf-DHHC PF01529.15 AIN98185.1 - 1.3 8.3 4.1 1.2 8.4 0.0 2.4 2 0 0 2 2 2 0 DHHC palmitoyltransferase ATP1G1_PLM_MAT8 PF02038.11 AIN98186.1 - 0.013 14.4 0.0 0.02 13.8 0.0 1.3 1 0 0 1 1 1 0 ATP1G1/PLM/MAT8 family DUF4499 PF14934.1 AIN98187.1 - 8.1e-07 28.8 2.6 1.3e-06 28.2 1.8 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4499) MutS_V PF00488.16 AIN98188.1 - 1.7e-33 116.0 0.0 3.4e-33 114.9 0.0 1.4 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 AIN98188.1 - 7.4e-16 58.5 0.7 3.2e-15 56.4 0.5 2.2 1 1 0 1 1 1 1 MutS domain III MutS_II PF05188.12 AIN98188.1 - 0.00054 20.0 0.1 0.0012 18.9 0.1 1.5 1 0 0 1 1 1 1 MutS domain II AAA_19 PF13245.1 AIN98188.1 - 0.0029 17.3 0.0 0.014 15.1 0.0 2.2 1 0 0 1 1 1 1 Part of AAA domain AAA_21 PF13304.1 AIN98188.1 - 0.0033 17.4 0.0 0.006 16.5 0.0 1.3 1 0 0 1 1 1 1 AAA domain Cut8_N PF14482.1 AIN98188.1 - 0.02 14.8 1.2 0.06 13.3 0.8 1.8 1 0 0 1 1 1 0 Cut8 proteasome-binding domain AAA_23 PF13476.1 AIN98188.1 - 0.021 15.1 0.5 0.037 14.3 0.4 1.3 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.1 AIN98188.1 - 0.022 14.6 0.0 0.04 13.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.22 AIN98188.1 - 0.041 14.1 0.2 0.1 12.9 0.1 1.6 1 0 0 1 1 1 0 ABC transporter AAA_22 PF13401.1 AIN98188.1 - 0.055 13.5 0.1 0.27 11.3 0.0 2.1 2 0 0 2 2 2 0 AAA domain Rnk_N PF14760.1 AIN98188.1 - 0.11 12.5 4.1 0.5 10.4 0.1 2.7 2 0 0 2 2 2 0 Rnk N-terminus Arch_ATPase PF01637.13 AIN98188.1 - 0.48 10.0 0.0 0.94 9.1 0.0 1.4 1 0 0 1 1 1 0 Archaeal ATPase tRNA-synt_2 PF00152.15 AIN98189.1 - 2.4e-65 220.4 0.0 5.7e-65 219.2 0.0 1.6 1 1 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 AIN98189.1 - 8.1e-07 28.8 0.0 1.6e-06 27.8 0.0 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.15 AIN98189.1 - 1.9e-06 27.2 0.1 0.0036 16.5 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) Mtf2_C PF14061.1 AIN98189.1 - 1.9 8.4 3.8 0.65 9.9 0.3 2.0 2 0 0 2 2 2 0 Polycomb-like MTF2 factor 2 MCR_alpha PF02249.12 AIN98190.1 - 0.096 12.6 0.2 0.5 10.3 0.1 2.0 2 0 0 2 2 2 0 Methyl-coenzyme M reductase alpha subunit, C-terminal domain tRNA_edit PF04073.10 AIN98192.1 - 3.1e-08 33.5 0.0 7.7e-08 32.2 0.0 1.7 1 1 0 1 1 1 1 Aminoacyl-tRNA editing domain Sugarporin_N PF11471.3 AIN98192.1 - 0.0079 15.8 0.1 0.017 14.7 0.1 1.6 1 0 0 1 1 1 1 Maltoporin periplasmic N-terminal extension DUF3138 PF11336.3 AIN98192.1 - 0.096 10.8 1.9 0.13 10.3 1.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) PDCD2_C PF04194.8 AIN98194.1 - 1.7e-29 102.5 8.6 2.4e-29 102.0 2.6 2.7 2 1 0 2 2 2 1 Programmed cell death protein 2, C-terminal putative domain Bim_N PF06773.6 AIN98195.1 - 0.025 14.3 0.5 0.025 14.3 0.3 4.1 4 1 1 5 5 5 0 Bim protein N-terminus Clathrin PF00637.15 AIN98197.1 - 3.6e-14 52.5 19.6 0.0098 15.5 0.0 10.5 7 3 6 13 13 12 3 Region in Clathrin and VPS WD40 PF00400.27 AIN98197.1 - 8.5e-11 41.3 1.6 0.25 11.2 0.1 6.4 7 0 0 7 7 6 3 WD domain, G-beta repeat TPR_7 PF13176.1 AIN98197.1 - 0.00013 21.5 26.6 2.1 8.3 0.0 12.2 12 3 2 14 14 14 1 Tetratricopeptide repeat Coatomer_WDAD PF04053.9 AIN98197.1 - 0.00017 20.5 11.1 0.039 12.7 0.2 5.6 4 2 2 6 6 6 2 Coatomer WD associated region TPR_12 PF13424.1 AIN98197.1 - 0.00027 20.7 35.1 0.78 9.7 0.2 11.2 11 1 1 12 12 11 2 Tetratricopeptide repeat PPR PF01535.15 AIN98197.1 - 0.0014 18.4 11.1 0.35 10.9 0.1 7.8 7 1 1 8 8 7 1 PPR repeat Apc3 PF12895.2 AIN98197.1 - 0.0019 18.2 23.3 0.083 13.0 0.0 7.5 5 3 2 8 8 8 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_1 PF00515.23 AIN98197.1 - 0.0048 16.4 34.4 5.2 6.8 0.1 10.8 10 1 1 11 11 11 2 Tetratricopeptide repeat TPR_14 PF13428.1 AIN98197.1 - 0.0058 17.1 47.0 5.7 7.8 0.0 15.9 14 5 3 17 17 16 1 Tetratricopeptide repeat zf-ribbon_3 PF13248.1 AIN98197.1 - 0.0095 15.1 0.0 0.034 13.3 0.0 2.0 1 1 0 1 1 1 1 zinc-ribbon domain TPR_4 PF07721.9 AIN98197.1 - 0.072 13.5 15.5 0.93 10.1 0.0 8.7 10 1 1 11 11 9 0 Tetratricopeptide repeat TPR_2 PF07719.12 AIN98197.1 - 0.081 12.8 48.1 0.22 11.5 0.0 12.3 14 1 1 15 15 13 0 Tetratricopeptide repeat PPR_2 PF13041.1 AIN98197.1 - 0.087 12.8 7.4 2.8 7.9 0.1 6.1 6 0 0 6 6 6 0 PPR repeat family PPR_3 PF13812.1 AIN98197.1 - 0.12 12.6 16.2 3.1 8.3 0.1 9.0 9 1 1 10 10 9 0 Pentatricopeptide repeat domain TPR_19 PF14559.1 AIN98197.1 - 0.3 11.4 23.7 0.81 10.0 0.0 8.5 8 2 2 10 10 8 0 Tetratricopeptide repeat TPR_11 PF13414.1 AIN98197.1 - 0.36 10.5 37.4 3.4 7.3 0.0 11.2 12 1 0 12 12 11 0 TPR repeat PPR_1 PF12854.2 AIN98197.1 - 0.56 9.7 2.7 0.58 9.6 0.2 2.5 2 0 0 2 2 2 0 PPR repeat Tubulin PF00091.20 AIN98200.1 - 1.5e-72 243.8 0.0 2.3e-72 243.3 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 AIN98200.1 - 3.9e-18 65.6 0.0 7.1e-18 64.8 0.0 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_2 PF13809.1 AIN98200.1 - 0.0011 17.9 0.0 0.0018 17.2 0.0 1.2 1 0 0 1 1 1 1 Tubulin like Misat_Tub_SegII PF10644.4 AIN98200.1 - 0.032 14.2 0.0 0.061 13.3 0.0 1.5 1 0 0 1 1 1 0 Misato Segment II tubulin-like domain GAS2 PF02187.12 AIN98200.1 - 0.046 13.4 0.0 0.19 11.5 0.0 2.0 2 0 0 2 2 2 0 Growth-Arrest-Specific Protein 2 Domain Tubulin_3 PF14881.1 AIN98200.1 - 0.12 11.8 0.0 0.25 10.7 0.0 1.5 1 0 0 1 1 1 0 Tubulin domain Ax_dynein_light PF10211.4 AIN98201.1 - 6.1e-50 169.7 4.2 9.9e-50 169.0 2.8 1.4 2 0 0 2 2 2 1 Axonemal dynein light chain CCDC66 PF15236.1 AIN98202.1 - 9e-05 22.1 41.1 9e-05 22.1 28.5 1.9 2 0 0 2 2 2 1 Coiled-coil domain-containing protein 66 Borrelia_P83 PF05262.6 AIN98202.1 - 0.0091 14.3 5.0 0.012 13.8 3.4 1.1 1 0 0 1 1 1 1 Borrelia P83/100 protein Kinesin PF00225.18 AIN98203.1 - 1.9e-85 286.5 0.3 3.3e-85 285.7 0.2 1.3 1 0 0 1 1 1 1 Kinesin motor domain Ribosomal_L6 PF00347.18 AIN98204.1 - 1.6e-26 92.6 2.1 7.6e-15 55.1 0.2 2.1 2 0 0 2 2 2 2 Ribosomal protein L6 Hormone_2 PF00123.15 AIN98204.1 - 0.046 13.5 0.0 30 4.5 0.0 3.1 3 0 0 3 3 3 0 Peptide hormone Ribosom_S12_S23 PF00164.20 AIN98205.1 - 2.3e-39 133.5 0.4 3.2e-39 133.1 0.3 1.2 1 0 0 1 1 1 1 Ribosomal protein S12/S23 Ribosom_S12_S23 PF00164.20 AIN98206.1 - 2.3e-39 133.5 0.4 3.2e-39 133.1 0.3 1.2 1 0 0 1 1 1 1 Ribosomal protein S12/S23 Pkinase PF00069.20 AIN98207.1 - 1.1e-74 250.9 0.0 1.2e-74 250.7 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AIN98207.1 - 3.7e-34 117.9 0.0 4.7e-34 117.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 AIN98207.1 - 0.001 18.8 0.4 0.11 12.1 0.1 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kinase-like PF14531.1 AIN98207.1 - 0.0068 15.3 0.0 0.091 11.7 0.0 2.1 1 1 0 2 2 2 1 Kinase-like Kdo PF06293.9 AIN98207.1 - 0.0071 15.4 0.4 0.014 14.4 0.3 1.4 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Cpn60_TCP1 PF00118.19 AIN98208.1 - 3.8e-135 451.2 7.6 4.4e-135 451.0 5.3 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Tau95 PF09734.4 AIN98209.1 - 7.1e-85 285.0 0.0 1.1e-84 284.4 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase III transcription factor (TF)IIIC subunit IQ PF00612.22 AIN98210.1 - 4.2e-17 60.0 205.0 0.00013 21.2 0.0 25.1 27 1 1 28 28 28 17 IQ calmodulin-binding motif TPR_1 PF00515.23 AIN98210.1 - 1.4e-05 24.4 0.0 1.2 8.8 0.0 4.1 3 0 0 3 3 3 3 Tetratricopeptide repeat WD40 PF00400.27 AIN98211.1 - 5.5e-14 51.4 13.6 0.00068 19.4 0.1 6.9 6 1 0 6 6 6 5 WD domain, G-beta repeat Nup160 PF11715.3 AIN98211.1 - 0.00071 17.8 0.1 0.0019 16.4 0.0 1.6 2 0 0 2 2 2 1 Nucleoporin Nup120/160 Nbas_N PF15492.1 AIN98211.1 - 0.003 16.7 0.1 0.067 12.2 0.1 2.5 1 1 0 2 2 2 1 Neuroblastoma-amplified sequence, N terminal PQQ_2 PF13360.1 AIN98211.1 - 0.28 10.6 5.0 0.86 9.0 0.4 3.4 2 1 1 3 3 3 0 PQQ-like domain AAA PF00004.24 AIN98212.1 - 0.035 14.3 0.1 0.089 12.9 0.1 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) bZIP_1 PF00170.16 AIN98212.1 - 0.069 13.1 14.0 0.76 9.7 0.1 4.0 3 1 0 3 3 3 0 bZIP transcription factor Reo_sigmaC PF04582.7 AIN98212.1 - 0.58 9.2 8.4 0.7 9.0 1.5 2.4 1 1 1 2 2 2 0 Reovirus sigma C capsid protein ATG16 PF08614.6 AIN98212.1 - 3.8 7.2 37.1 1.1 9.0 4.7 3.3 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) DUF3801 PF12687.2 AIN98212.1 - 4.3 6.8 8.1 7.1 6.1 5.5 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3801) LRR_8 PF13855.1 AIN98216.1 - 1.7e-26 91.7 18.4 1.2e-07 31.3 0.6 5.5 1 1 7 8 8 8 8 Leucine rich repeat LRR_1 PF00560.28 AIN98216.1 - 1.1e-21 73.5 2.6 0.14 12.2 0.0 11.6 12 0 0 12 12 12 4 Leucine Rich Repeat LRR_4 PF12799.2 AIN98216.1 - 1.4e-19 69.2 11.1 0.00039 19.9 0.9 6.7 3 3 4 7 7 7 7 Leucine Rich repeats (2 copies) LRR_7 PF13504.1 AIN98216.1 - 0.0002 21.0 33.8 3.2 8.3 0.1 10.6 11 0 0 11 11 11 4 Leucine rich repeat LRR_6 PF13516.1 AIN98216.1 - 0.0012 18.6 22.1 5.3 7.4 0.1 9.4 11 1 1 12 12 12 1 Leucine Rich repeat Ribosomal_L1 PF00687.16 AIN98217.1 - 3.6e-10 39.5 0.0 3.7e-09 36.2 0.0 2.0 1 1 0 1 1 1 1 Ribosomal protein L1p/L10e family PIF1 PF05970.9 AIN98218.1 - 6.4e-34 117.4 0.1 3.3e-24 85.5 0.0 3.7 2 1 1 3 3 3 3 PIF1-like helicase AAA_30 PF13604.1 AIN98218.1 - 4.2e-11 42.8 2.1 4e-09 36.3 0.9 2.6 2 0 0 2 2 2 1 AAA domain Viral_helicase1 PF01443.13 AIN98218.1 - 1.8e-06 27.6 0.1 0.17 11.3 0.0 3.4 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase AAA_19 PF13245.1 AIN98218.1 - 2.1e-06 27.4 2.4 2.1e-06 27.4 1.7 2.0 2 0 0 2 2 1 1 Part of AAA domain DEAD PF00270.24 AIN98218.1 - 9.7e-05 21.9 0.0 0.037 13.5 0.0 2.5 2 0 0 2 2 2 2 DEAD/DEAH box helicase UvrD_C_2 PF13538.1 AIN98218.1 - 0.00089 19.3 0.0 0.0022 18.1 0.0 1.6 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_22 PF13401.1 AIN98218.1 - 0.0021 18.2 0.0 0.005 16.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain UvrD-helicase PF00580.16 AIN98218.1 - 0.0029 16.9 0.0 0.0048 16.2 0.0 1.3 1 0 0 1 1 1 1 UvrD/REP helicase N-terminal domain AAA_11 PF13086.1 AIN98218.1 - 0.0033 17.0 0.9 0.1 12.1 0.0 2.6 1 1 1 2 2 2 1 AAA domain AAA_32 PF13654.1 AIN98218.1 - 0.0044 15.7 0.0 0.007 15.0 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.9 AIN98218.1 - 0.0053 16.4 0.0 0.4 10.3 0.0 2.4 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) PhoH PF02562.11 AIN98218.1 - 0.0068 15.6 0.0 0.013 14.7 0.0 1.4 1 0 0 1 1 1 1 PhoH-like protein Mg_chelatase PF01078.16 AIN98218.1 - 0.011 14.9 0.2 0.02 14.0 0.1 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Herpes_Helicase PF02689.9 AIN98218.1 - 0.038 11.7 0.1 0.18 9.5 0.0 2.0 3 0 0 3 3 3 0 Helicase DUF2075 PF09848.4 AIN98218.1 - 0.083 11.8 0.0 0.16 10.9 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) NTPase_1 PF03266.10 AIN98218.1 - 0.095 12.4 0.0 0.29 10.8 0.0 1.7 1 1 0 1 1 1 0 NTPase Ribosomal_L29 PF00831.18 AIN98219.1 - 0.038 13.6 0.2 0.038 13.6 0.1 1.8 2 0 0 2 2 2 0 Ribosomal L29 protein TK PF00265.13 AIN98220.1 - 6.8e-62 208.1 0.9 9.5e-62 207.6 0.6 1.2 1 0 0 1 1 1 1 Thymidine kinase AAA_14 PF13173.1 AIN98220.1 - 0.00085 19.2 0.0 0.0017 18.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain DUF1489 PF07370.6 AIN98220.1 - 0.092 12.2 0.0 0.16 11.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1489) Cytochrome_C7 PF14522.1 AIN98220.1 - 0.1 12.2 1.5 0.22 11.1 1.0 1.6 1 0 0 1 1 1 0 Cytochrome c7 WD40 PF00400.27 AIN98222.1 - 2.8e-16 58.6 11.7 1.1e-07 31.4 0.1 4.6 5 0 0 5 5 5 2 WD domain, G-beta repeat DUF3232 PF11554.3 AIN98222.1 - 9.3 6.1 8.8 2.2 8.1 0.5 3.4 4 0 0 4 4 4 0 Protein of unknown function (DUF3232) ADK PF00406.17 AIN98223.1 - 1.5e-37 128.7 0.0 2.1e-37 128.3 0.0 1.2 1 0 0 1 1 1 1 Adenylate kinase AAA_18 PF13238.1 AIN98223.1 - 4.3e-06 27.0 0.0 2e-05 24.8 0.0 2.0 2 0 0 2 2 2 1 AAA domain ADK_lid PF05191.9 AIN98223.1 - 4.5e-06 26.2 0.1 2.5e-05 23.8 0.0 2.2 2 0 0 2 2 2 1 Adenylate kinase, active site lid AAA_17 PF13207.1 AIN98223.1 - 0.00023 21.9 0.0 0.00068 20.4 0.0 1.8 1 1 1 2 2 2 1 AAA domain AAA_33 PF13671.1 AIN98223.1 - 0.00042 20.2 0.0 0.00095 19.0 0.0 1.5 2 0 0 2 2 2 1 AAA domain LRR_6 PF13516.1 AIN98224.1 - 0.00011 21.9 1.6 5.8 7.3 0.3 3.7 3 0 0 3 3 3 2 Leucine Rich repeat LRR_4 PF12799.2 AIN98224.1 - 0.012 15.1 0.5 0.44 10.2 0.4 2.4 1 1 0 1 1 1 0 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 AIN98224.1 - 0.047 13.7 3.1 11 6.4 0.2 3.5 2 1 1 3 3 3 0 Leucine Rich Repeat Serine_rich PF08824.5 AIN98225.1 - 0.013 15.1 0.0 0.044 13.4 0.0 1.8 1 0 0 1 1 1 0 Serine rich protein interaction domain Mito_fiss_reg PF05308.6 AIN98225.1 - 0.034 13.5 0.6 0.071 12.4 0.4 1.4 1 0 0 1 1 1 0 Mitochondrial fission regulator Yippee-Mis18 PF03226.9 AIN98226.1 - 0.12 12.4 0.8 0.76 9.8 0.6 2.0 1 1 0 1 1 1 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly Synaptobrevin PF00957.16 AIN98227.1 - 1.3e-25 88.8 1.2 1.9e-25 88.2 0.8 1.2 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.1 AIN98227.1 - 0.049 13.2 0.0 0.084 12.4 0.0 1.3 1 0 0 1 1 1 0 Regulated-SNARE-like domain NMO PF03060.10 AIN98228.1 - 6.6e-72 242.4 1.6 4.7e-71 239.6 1.1 1.8 1 1 0 1 1 1 1 Nitronate monooxygenase FMN_dh PF01070.13 AIN98228.1 - 1.4e-08 34.0 0.4 2.3e-08 33.2 0.3 1.3 1 0 0 1 1 1 1 FMN-dependent dehydrogenase IMPDH PF00478.20 AIN98228.1 - 8.3e-08 31.4 0.1 0.00013 21.0 0.8 2.2 1 1 1 2 2 2 2 IMP dehydrogenase / GMP reductase domain DHO_dh PF01180.16 AIN98228.1 - 2.3e-07 30.0 0.2 8.1e-07 28.2 0.2 1.7 2 0 0 2 2 2 1 Dihydroorotate dehydrogenase ThiG PF05690.9 AIN98228.1 - 1.8e-05 23.9 0.6 2.9e-05 23.2 0.4 1.2 1 0 0 1 1 1 1 Thiazole biosynthesis protein ThiG Glu_synthase PF01645.12 AIN98228.1 - 0.0019 17.1 2.0 0.0036 16.2 1.4 1.5 1 1 0 1 1 1 1 Conserved region in glutamate synthase Dus PF01207.12 AIN98228.1 - 0.005 15.7 0.1 0.023 13.5 0.0 2.0 2 0 0 2 2 2 1 Dihydrouridine synthase (Dus) NanE PF04131.9 AIN98228.1 - 0.028 13.4 0.1 0.047 12.6 0.1 1.3 1 0 0 1 1 1 0 Putative N-acetylmannosamine-6-phosphate epimerase His_biosynth PF00977.16 AIN98228.1 - 0.05 12.8 0.1 0.082 12.1 0.1 1.4 1 0 0 1 1 1 0 Histidine biosynthesis protein zf-RING_2 PF13639.1 AIN98229.1 - 3.3e-10 39.6 4.1 3.7e-08 33.0 1.0 2.3 2 0 0 2 2 2 2 Ring finger domain zf-rbx1 PF12678.2 AIN98229.1 - 6.5e-09 35.7 0.2 1.6e-06 28.1 0.1 2.3 2 0 0 2 2 2 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 AIN98229.1 - 4.7e-06 26.1 2.4 1.5e-05 24.5 0.2 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 AIN98229.1 - 0.00013 21.7 0.4 0.00026 20.7 0.3 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_2 PF13923.1 AIN98229.1 - 0.00027 20.9 5.5 0.00028 20.8 1.2 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 AIN98229.1 - 0.0026 17.3 3.0 0.0087 15.7 0.4 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 AIN98229.1 - 0.023 14.4 1.9 0.063 13.0 0.3 2.1 2 0 0 2 2 2 0 zinc-RING finger domain zf-RING_4 PF14570.1 AIN98229.1 - 0.91 9.1 3.4 0.23 11.0 0.2 1.6 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-C3HC4_4 PF15227.1 AIN98229.1 - 6.1 6.8 6.2 0.55 10.1 0.7 1.9 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING RF-1 PF00472.15 AIN98230.1 - 2.5e-10 40.1 0.6 2.5e-10 40.1 0.4 3.5 4 0 0 4 4 4 1 RF-1 domain GAS PF13851.1 AIN98230.1 - 0.00031 19.9 14.5 0.00031 19.9 10.1 2.5 4 0 0 4 4 4 1 Growth-arrest specific micro-tubule binding CCDC155 PF14662.1 AIN98230.1 - 0.0084 15.7 14.7 0.0084 15.7 10.2 3.3 3 1 0 3 3 3 1 Coiled-coil region of CCDC155 Peptidase_S51 PF03575.12 AIN98230.1 - 0.033 13.9 0.1 0.15 11.7 0.0 2.1 2 0 0 2 2 2 0 Peptidase family S51 Reo_sigmaC PF04582.7 AIN98230.1 - 0.16 11.1 5.4 0.28 10.3 3.2 1.8 1 1 0 1 1 1 0 Reovirus sigma C capsid protein Laminin_II PF06009.7 AIN98230.1 - 0.23 11.2 9.4 1.2 8.8 6.4 2.4 1 1 0 1 1 1 0 Laminin Domain II MxiH PF09392.5 AIN98230.1 - 0.26 11.8 0.0 0.26 11.8 0.0 4.5 3 1 1 4 4 3 0 Type III secretion needle MxiH like EAP30 PF04157.11 AIN98230.1 - 0.51 9.4 11.9 0.63 9.1 0.4 2.9 2 1 1 3 3 3 0 EAP30/Vps36 family DUF4250 PF14056.1 AIN98230.1 - 0.83 9.4 5.3 0.26 11.0 0.1 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4250) CDC37_N PF03234.9 AIN98230.1 - 1 9.6 16.7 0.33 11.2 5.1 2.9 3 0 0 3 3 3 0 Cdc37 N terminal kinase binding LMBR1 PF04791.11 AIN98230.1 - 1 7.8 1.9 1.7 7.1 1.3 1.3 1 0 0 1 1 1 0 LMBR1-like membrane protein CALCOCO1 PF07888.6 AIN98230.1 - 1.2 7.3 17.2 0.013 13.8 5.7 2.1 3 0 0 3 3 3 0 Calcium binding and coiled-coil domain (CALCOCO1) like DUF972 PF06156.8 AIN98230.1 - 5 7.5 15.8 2.8 8.3 3.0 3.6 2 1 1 3 3 3 0 Protein of unknown function (DUF972) DUF4044 PF13253.1 AIN98232.1 - 0.12 11.5 1.0 0.19 10.9 0.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4044) SMC_N PF02463.14 AIN98233.1 - 4.9e-73 244.9 1.6 1.5e-35 122.4 0.7 3.0 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 AIN98233.1 - 2.9e-22 78.8 0.7 9e-22 77.2 0.0 2.3 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.1 AIN98233.1 - 5e-13 49.6 0.2 4e-06 27.0 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_23 PF13476.1 AIN98233.1 - 4.4e-12 46.7 0.4 4.4e-12 46.7 0.3 5.8 2 2 1 4 4 4 1 AAA domain AAA_29 PF13555.1 AIN98233.1 - 6.7e-06 25.5 0.0 1.4e-05 24.5 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_15 PF13175.1 AIN98233.1 - 4.2e-05 22.7 0.2 0.0074 15.3 0.0 2.6 2 0 0 2 2 2 2 AAA ATPase domain DUF948 PF06103.6 AIN98233.1 - 0.0074 16.1 2.3 0.19 11.6 0.1 3.6 2 0 0 2 2 2 1 Bacterial protein of unknown function (DUF948) ABC_tran PF00005.22 AIN98233.1 - 0.089 13.0 0.0 0.089 13.0 0.0 5.1 4 2 0 4 4 4 0 ABC transporter DUF4544 PF15077.1 AIN98233.1 - 0.77 9.2 0.0 0.77 9.2 0.0 4.1 4 1 1 5 5 5 0 Domain of unknown function (DUF4544) V-ATPase_H_N PF03224.9 AIN98234.1 - 2.9e-67 226.9 0.6 4.2e-67 226.4 0.4 1.2 1 0 0 1 1 1 1 V-ATPase subunit H V-ATPase_H_C PF11698.3 AIN98234.1 - 5.4e-43 145.7 0.1 3.6e-42 143.0 0.0 2.1 2 0 0 2 2 2 1 V-ATPase subunit H PB1 PF00564.19 AIN98235.1 - 1.1e-06 28.2 0.0 2.5e-06 27.0 0.0 1.6 1 0 0 1 1 1 1 PB1 domain zf-DHHC PF01529.15 AIN98239.1 - 4.1e-33 114.2 1.1 4.1e-33 114.2 0.8 1.7 2 0 0 2 2 2 1 DHHC palmitoyltransferase DUF588 PF04535.7 AIN98239.1 - 0.049 13.1 1.5 0.11 12.0 1.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF588) DUF971 PF06155.7 AIN98240.1 - 1.5e-18 67.0 0.0 6e-15 55.4 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF971) DUF1970 PF09301.5 AIN98240.1 - 0.26 11.3 0.2 0.26 11.3 0.1 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF1970) DUF393 PF04134.7 AIN98241.1 - 0.0034 18.4 1.3 0.092 13.8 0.3 2.4 2 1 0 2 2 2 1 Protein of unknown function, DUF393 E1_dh PF00676.15 AIN98242.1 - 4.9e-79 265.1 0.0 6.4e-79 264.7 0.0 1.1 1 0 0 1 1 1 1 Dehydrogenase E1 component DUF4440 PF14534.1 AIN98242.1 - 0.084 13.0 0.0 0.29 11.3 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4440) Cyt-b5 PF00173.23 AIN98243.1 - 2.9e-09 36.6 0.0 4.7e-09 35.9 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain PRMT5 PF05185.11 AIN98244.1 - 5.5e-71 239.8 0.0 7.5e-71 239.3 0.0 1.2 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase TPR_12 PF13424.1 AIN98246.1 - 0.00019 21.3 5.4 0.007 16.2 0.3 3.2 2 1 1 3 3 3 2 Tetratricopeptide repeat MIT PF04212.13 AIN98246.1 - 0.0026 17.6 7.1 0.023 14.5 0.0 3.2 3 1 1 4 4 4 2 MIT (microtubule interacting and transport) domain TPR_2 PF07719.12 AIN98246.1 - 0.029 14.2 5.6 0.066 13.1 0.4 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat Hemerythrin PF01814.18 AIN98246.1 - 0.045 13.8 0.7 0.38 10.8 0.0 2.6 3 0 0 3 3 3 0 Hemerythrin HHE cation binding domain Apc3 PF12895.2 AIN98246.1 - 0.057 13.5 0.9 0.65 10.1 0.2 2.8 3 0 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_11 PF13414.1 AIN98246.1 - 0.12 12.0 8.4 0.12 12.0 0.6 3.3 3 2 0 3 3 3 0 TPR repeat KdpC PF02669.10 AIN98246.1 - 0.13 11.8 0.5 0.4 10.3 0.3 1.6 1 1 1 2 2 2 0 K+-transporting ATPase, c chain TPR_1 PF00515.23 AIN98246.1 - 0.19 11.3 6.3 0.49 10.0 1.3 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat PAT1 PF09770.4 AIN98248.1 - 3.3 5.8 8.1 5.3 5.1 5.6 1.3 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Mut7-C PF01927.11 AIN98250.1 - 0.0086 16.0 0.0 0.56 10.1 0.0 2.7 2 0 0 2 2 2 2 Mut7-C RNAse domain HMG_box_2 PF09011.5 AIN98251.1 - 7.8e-06 26.1 3.3 0.006 16.9 0.3 3.1 3 0 0 3 3 3 2 HMG-box domain HMG_box PF00505.14 AIN98251.1 - 2.5e-05 24.4 2.6 0.0013 18.9 0.5 3.2 3 1 0 3 3 3 1 HMG (high mobility group) box Sec8_exocyst PF04048.9 AIN98252.1 - 2.9e-11 43.1 0.2 7.1e-11 41.9 0.1 1.6 1 0 0 1 1 1 1 Sec8 exocyst complex component specific domain DUF2450 PF10475.4 AIN98252.1 - 1.8e-05 23.8 0.6 3.7e-05 22.7 0.4 1.5 1 0 0 1 1 1 1 Protein of unknown function N-terminal domain (DUF2450) Nop14 PF04147.7 AIN98252.1 - 0.00027 19.0 4.5 0.00043 18.3 3.1 1.2 1 0 0 1 1 1 1 Nop14-like family CDC45 PF02724.9 AIN98252.1 - 1.8 6.4 9.3 4.2 5.2 6.4 1.5 1 0 0 1 1 1 0 CDC45-like protein Ribosomal_S17 PF00366.15 AIN98253.1 - 9.5e-26 89.6 1.2 9.5e-26 89.6 0.9 2.0 2 0 0 2 2 2 1 Ribosomal protein S17 DUF4018 PF13210.1 AIN98254.1 - 0.00012 21.5 0.4 0.0002 20.8 0.3 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4018) MSA-2c PF12238.3 AIN98254.1 - 0.18 11.4 0.1 0.34 10.5 0.1 1.4 1 0 0 1 1 1 0 Merozoite surface antigen 2c Sigma_reg_N PF13800.1 AIN98254.1 - 4.5 7.3 8.6 0.087 12.8 0.4 2.3 3 0 0 3 3 3 0 Sigma factor regulator N-terminal DEAD PF00270.24 AIN98255.1 - 5e-35 120.4 0.5 1.1e-33 116.0 0.1 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 AIN98255.1 - 3.2e-22 78.1 0.6 1e-21 76.5 0.1 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 AIN98255.1 - 9.8e-07 28.7 0.0 2.2e-06 27.6 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CMS1 PF14617.1 AIN98255.1 - 0.0042 16.1 2.5 0.012 14.7 0.0 2.7 2 1 1 4 4 4 1 U3-containing 90S pre-ribosomal complex subunit Helicase_C_2 PF13307.1 AIN98255.1 - 0.068 13.1 0.7 0.18 11.7 0.0 2.0 2 0 0 2 2 2 0 Helicase C-terminal domain LETM1 PF07766.8 AIN98256.1 - 5.4e-05 22.3 0.0 9.5e-05 21.5 0.0 1.3 1 0 0 1 1 1 1 LETM1-like protein Tn7_Tnp_TnsA_N PF08722.6 AIN98256.1 - 0.036 14.0 0.1 0.084 12.8 0.0 1.6 1 0 0 1 1 1 0 TnsA endonuclease N terminal GST_C_2 PF13410.1 AIN98257.1 - 0.00014 21.6 0.4 0.00039 20.2 0.0 1.9 2 1 1 3 3 3 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 AIN98257.1 - 0.0013 19.2 0.0 0.0022 18.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 AIN98257.1 - 0.095 12.7 0.0 0.34 10.9 0.0 2.0 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain GMC_oxred_N PF00732.14 AIN98259.1 - 2e-12 46.8 0.0 2.8e-12 46.3 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 AIN98259.1 - 1.8e-11 44.4 0.0 3e-10 40.5 0.0 2.4 2 1 0 2 2 2 1 GMC oxidoreductase Lycopene_cycl PF05834.7 AIN98259.1 - 0.00011 21.3 0.0 0.0027 16.6 0.0 2.5 3 0 0 3 3 3 1 Lycopene cyclase protein DAO PF01266.19 AIN98259.1 - 0.00056 18.9 2.8 0.0013 17.7 0.0 2.6 2 1 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 AIN98259.1 - 0.0017 18.3 0.3 0.006 16.5 0.2 1.9 1 1 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.9 AIN98259.1 - 0.0025 16.3 0.2 0.0036 15.8 0.2 1.2 1 0 0 1 1 1 1 HI0933-like protein Thi4 PF01946.12 AIN98259.1 - 0.0076 15.3 0.5 0.0076 15.3 0.3 1.8 2 0 0 2 2 2 1 Thi4 family FAD_binding_2 PF00890.19 AIN98259.1 - 0.009 14.9 0.1 0.016 14.0 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 AIN98259.1 - 0.064 13.1 0.0 0.13 12.1 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pkinase PF00069.20 AIN98260.1 - 4.9e-68 229.0 0.0 9.4e-68 228.1 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AIN98260.1 - 1.2e-44 152.4 0.0 2e-44 151.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 AIN98260.1 - 6.5e-07 28.5 0.3 1.5e-06 27.3 0.0 1.8 2 0 0 2 2 2 1 Kinase-like RIO1 PF01163.17 AIN98260.1 - 0.013 14.8 0.0 0.013 14.8 0.0 2.3 3 0 0 3 3 3 0 RIO1 family MIP-T3 PF10243.4 AIN98261.1 - 1.7e-100 337.0 42.3 3.4e-65 220.5 7.5 2.0 1 1 1 2 2 2 2 Microtubule-binding protein MIP-T3 Reo_sigmaC PF04582.7 AIN98261.1 - 0.0023 17.1 1.9 0.0044 16.2 1.3 1.4 1 0 0 1 1 1 1 Reovirus sigma C capsid protein Filo_glycop PF01611.11 AIN98261.1 - 0.11 11.3 10.0 0.26 10.0 0.2 2.2 2 0 0 2 2 2 0 Filovirus glycoprotein TFIIF_alpha PF05793.7 AIN98261.1 - 0.12 10.7 24.3 0.16 10.3 16.8 1.3 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) peroxidase PF00141.18 AIN98263.1 - 3.2e-11 43.1 0.0 5.3e-10 39.1 0.0 2.2 1 1 1 2 2 2 1 Peroxidase DUF4094 PF13334.1 AIN98263.1 - 0.072 13.4 0.3 1.9 8.9 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4094) DUF4131 PF13567.1 AIN98263.1 - 0.17 11.3 0.3 0.52 9.6 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) WD40 PF00400.27 AIN98264.1 - 0.29 11.0 4.5 22 5.1 0.3 3.9 3 0 0 3 3 3 0 WD domain, G-beta repeat Nodulin-like PF06813.8 AIN98265.1 - 1.7e-06 27.4 10.4 1.7e-06 27.4 7.2 2.8 3 0 0 3 3 3 1 Nodulin-like MFS_1 PF07690.11 AIN98265.1 - 0.00026 19.8 27.6 0.00026 19.8 19.1 2.9 2 1 0 2 2 2 1 Major Facilitator Superfamily Cyt_c_ox_IV PF12270.3 AIN98265.1 - 0.22 11.2 7.7 0.31 10.8 0.0 4.2 4 0 0 4 4 4 0 Cytochrome c oxidase subunit IV F-box-like PF12937.2 AIN98266.1 - 7.8e-08 31.9 1.9 2.4e-07 30.3 1.3 1.9 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 AIN98266.1 - 4e-05 23.1 3.0 0.00016 21.1 2.1 2.1 1 0 0 1 1 1 1 F-box domain Tic20 PF09685.5 AIN98266.1 - 0.032 14.1 1.0 0.032 14.1 0.7 3.6 3 1 0 3 3 3 0 Tic20-like protein DUF1673 PF07895.6 AIN98266.1 - 0.64 9.5 12.5 0.46 9.9 4.9 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF1673) ATG16 PF08614.6 AIN98267.1 - 0.012 15.4 2.8 0.087 12.6 0.6 2.1 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) IL10 PF00726.12 AIN98267.1 - 0.05 12.9 1.2 0.46 9.7 0.4 2.2 2 1 0 2 2 2 0 Interleukin 10 zf-Sec23_Sec24 PF04810.10 AIN98268.1 - 0.026 14.0 0.5 0.026 14.0 0.4 2.6 3 0 0 3 3 3 0 Sec23/Sec24 zinc finger PHD PF00628.24 AIN98268.1 - 2.3 7.9 6.8 0.2 11.3 0.8 2.0 2 0 0 2 2 2 0 PHD-finger Rubredoxin PF00301.15 AIN98268.1 - 3.7 7.5 6.3 2.7 7.9 0.4 2.3 2 0 0 2 2 2 0 Rubredoxin zf-MIZ PF02891.15 AIN98268.1 - 8.1 6.0 7.7 0.2 11.2 0.4 1.9 2 0 0 2 2 2 0 MIZ/SP-RING zinc finger DUF2407 PF10302.4 AIN98269.1 - 0.13 12.4 0.1 0.21 11.8 0.1 1.4 1 1 0 1 1 1 0 DUF2407 ubiquitin-like domain PPR_2 PF13041.1 AIN98270.1 - 8.5e-09 35.2 0.1 2.2e-08 33.9 0.0 1.7 1 0 0 1 1 1 1 PPR repeat family PPR_3 PF13812.1 AIN98270.1 - 7e-06 25.9 2.6 4e-05 23.5 0.1 3.4 5 0 0 5 5 5 1 Pentatricopeptide repeat domain PPR PF01535.15 AIN98270.1 - 0.00012 21.8 0.8 0.00036 20.3 0.0 2.3 3 0 0 3 3 3 1 PPR repeat PPR_1 PF12854.2 AIN98270.1 - 0.12 11.8 0.0 0.41 10.1 0.0 1.8 2 0 0 2 2 2 0 PPR repeat TPR_12 PF13424.1 AIN98270.1 - 0.17 11.8 1.2 0.33 10.9 0.8 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat EF-hand_7 PF13499.1 AIN98271.1 - 2.6e-25 88.3 12.4 5.1e-11 42.5 1.1 2.9 1 1 2 3 3 3 3 EF-hand domain pair EF-hand_1 PF00036.27 AIN98271.1 - 3.9e-24 82.0 8.5 1e-06 27.5 0.1 4.5 5 0 0 5 5 5 4 EF hand EF-hand_6 PF13405.1 AIN98271.1 - 4.6e-19 66.5 7.8 9.9e-05 21.9 0.2 5.0 5 0 0 5 5 5 4 EF-hand domain EF-hand_5 PF13202.1 AIN98271.1 - 1.8e-16 58.6 14.0 6.5e-07 28.4 0.2 4.8 5 0 0 5 5 5 4 EF hand EF-hand_8 PF13833.1 AIN98271.1 - 5.6e-16 57.8 9.3 1.6e-05 24.4 0.6 4.3 1 1 3 4 4 4 4 EF-hand domain pair EF-hand_4 PF12763.2 AIN98271.1 - 1.3e-06 28.1 1.6 0.21 11.3 0.1 3.4 1 1 3 4 4 4 3 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.4 AIN98271.1 - 3e-06 27.2 0.0 0.0022 17.9 0.0 2.2 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region Capsule_synth PF05159.9 AIN98271.1 - 0.0054 16.2 0.0 0.0079 15.7 0.0 1.2 1 0 0 1 1 1 1 Capsule polysaccharide biosynthesis protein DUF1425 PF07233.7 AIN98271.1 - 0.13 11.8 0.0 0.22 11.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1425) Dockerin_1 PF00404.13 AIN98271.1 - 6.9 6.5 8.8 9 6.1 0.3 3.4 3 0 0 3 3 3 0 Dockerin type I repeat POR_N PF01855.14 AIN98272.1 - 0.13 11.7 0.3 0.28 10.6 0.1 1.6 1 1 0 1 1 1 0 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg Pkinase PF00069.20 AIN98273.1 - 9.8e-42 142.8 0.0 1.2e-41 142.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AIN98273.1 - 1.6e-10 40.5 0.0 2.8e-10 39.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 AIN98273.1 - 0.034 13.8 0.0 0.072 12.8 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family 5_3_exonuc PF01367.15 AIN98274.1 - 4.9e-18 65.2 0.0 8.5e-18 64.4 0.0 1.4 1 0 0 1 1 1 1 5'-3' exonuclease, C-terminal SAM fold 5_3_exonuc_N PF02739.11 AIN98274.1 - 3.3e-15 55.8 0.5 3.5e-12 46.0 0.3 3.0 1 1 0 1 1 1 1 5'-3' exonuclease, N-terminal resolvase-like domain zf-MYND PF01753.13 AIN98276.1 - 0.0018 18.0 19.9 0.0039 17.0 13.8 1.6 1 0 0 1 1 1 1 MYND finger PUF PF00806.14 AIN98277.1 - 6.7e-49 160.7 6.5 8.5e-06 24.9 0.0 8.4 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat CPL PF08144.6 AIN98277.1 - 0.042 13.6 0.2 7.8 6.3 0.0 3.4 2 2 1 3 3 3 0 CPL (NUC119) domain HNOB PF07700.10 AIN98277.1 - 0.052 13.0 0.0 2.8 7.4 0.0 3.1 3 0 0 3 3 3 0 Heme NO binding DUF607 PF04678.8 AIN98278.1 - 2.5e-50 170.8 2.7 3.5e-50 170.4 1.9 1.2 1 0 0 1 1 1 1 Protein of unknown function, DUF607 SYS1 PF09801.4 AIN98278.1 - 0.096 12.6 2.0 0.15 12.0 1.4 1.3 1 0 0 1 1 1 0 Integral membrane protein S linking to the trans Golgi network Proteasome PF00227.21 AIN98279.1 - 6.6e-64 214.6 0.0 1e-63 214.0 0.0 1.3 1 1 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 AIN98279.1 - 8.5e-10 37.7 0.7 4.5e-09 35.4 0.1 2.1 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature RecA PF00154.16 AIN98279.1 - 0.021 13.9 0.0 0.072 12.1 0.0 1.8 2 0 0 2 2 2 0 recA bacterial DNA recombination protein YadA_head PF05658.9 AIN98279.1 - 0.49 10.7 5.6 1 9.6 0.6 2.4 2 0 0 2 2 2 0 Head domain of trimeric autotransporter adhesin Ribosomal_L32e PF01655.13 AIN98281.1 - 1.4e-39 134.4 0.2 1.7e-39 134.2 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein L32 PEHE PF15275.1 AIN98282.1 - 0.0043 17.5 4.1 0.0043 17.5 2.8 2.0 1 1 1 2 2 2 1 PEHE domain Abi_HHR PF07815.9 AIN98282.1 - 0.12 12.4 0.5 0.26 11.4 0.4 1.6 1 0 0 1 1 1 0 Abl-interactor HHR Wbp11 PF09429.5 AIN98282.1 - 0.49 10.4 19.0 0.052 13.5 6.8 2.4 2 0 0 2 2 2 0 WW domain binding protein 11 Hph PF13694.1 AIN98282.1 - 6.4 6.7 10.5 0.61 10.0 3.3 2.0 1 1 1 2 2 2 0 Sec63/Sec62 complex-interacting family PAP_assoc PF03828.14 AIN98283.1 - 1.3e-05 25.0 0.4 7.7e-05 22.5 0.1 2.3 2 0 0 2 2 2 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.18 AIN98283.1 - 0.086 13.1 0.0 0.26 11.6 0.0 1.8 1 0 0 1 1 1 0 Nucleotidyltransferase domain SET PF00856.23 AIN98284.1 - 3.7e-07 30.6 0.3 8.8e-05 22.8 0.0 2.8 2 1 1 3 3 3 2 SET domain PHD PF00628.24 AIN98284.1 - 0.039 13.6 11.4 0.15 11.8 7.9 2.1 1 1 0 1 1 1 0 PHD-finger DKCLD PF08068.7 AIN98285.1 - 8.9e-28 96.0 0.0 9.7e-27 92.6 0.0 2.6 2 0 0 2 2 2 1 DKCLD (NUC011) domain TruB_N PF01509.13 AIN98285.1 - 1e-22 80.8 2.0 3.3e-19 69.5 1.4 3.3 1 1 0 1 1 1 1 TruB family pseudouridylate synthase (N terminal domain) PUA PF01472.15 AIN98285.1 - 5.8e-20 70.8 1.0 1.1e-19 69.9 0.7 1.5 1 0 0 1 1 1 1 PUA domain ATP-synt PF00231.14 AIN98286.1 - 5.5e-34 117.8 1.2 6.6e-34 117.5 0.8 1.1 1 0 0 1 1 1 1 ATP synthase Ribosomal_S6e PF01092.14 AIN98287.1 - 5.3e-39 132.7 0.3 9.7e-39 131.9 0.2 1.4 1 0 0 1 1 1 1 Ribosomal protein S6e RdRP_3 PF00998.18 AIN98287.1 - 0.46 8.9 6.2 0.55 8.6 4.3 1.1 1 0 0 1 1 1 0 Viral RNA dependent RNA polymerase ATP-synt_C PF00137.16 AIN98288.1 - 6.1e-25 86.9 36.1 1.3e-17 63.4 7.4 3.0 3 0 0 3 3 3 2 ATP synthase subunit C TF_Otx PF03529.8 AIN98288.1 - 0.0085 16.2 0.9 0.015 15.4 0.6 1.4 1 0 0 1 1 1 1 Otx1 transcription factor Flavi_NS4A PF01350.12 AIN98288.1 - 0.086 12.4 1.2 5.6 6.5 0.0 2.2 2 0 0 2 2 2 0 Flavivirus non-structural protein NS4A GerA PF03323.8 AIN98288.1 - 0.19 9.8 3.5 1.8 6.6 0.3 2.1 2 0 0 2 2 2 0 Bacillus/Clostridium GerA spore germination protein DUF998 PF06197.8 AIN98288.1 - 0.95 8.7 18.4 0.09 12.0 6.3 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF998) ABC2_membrane_5 PF13346.1 AIN98288.1 - 2.2 7.5 8.3 0.47 9.7 1.6 2.2 2 1 0 2 2 2 0 ABC-2 family transporter protein Gaa1 PF04114.9 AIN98289.1 - 8e-07 28.1 4.7 2.3e-06 26.6 3.2 1.7 1 1 0 1 1 1 1 Gaa1-like, GPI transamidase component Ribosomal_L37ae PF01780.14 AIN98290.1 - 2.6e-36 123.3 5.1 3e-36 123.1 3.6 1.0 1 0 0 1 1 1 1 Ribosomal L37ae protein family C1_1 PF00130.17 AIN98290.1 - 0.00088 18.9 2.1 0.0013 18.4 1.4 1.2 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) A2L_zn_ribbon PF08792.5 AIN98290.1 - 0.03 13.7 1.2 2.1 7.8 0.0 2.1 2 0 0 2 2 2 0 A2L zinc ribbon domain UPF0547 PF10571.4 AIN98290.1 - 0.057 13.1 1.1 8 6.2 0.0 2.2 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 Carla_C4 PF01623.12 AIN98290.1 - 0.11 12.2 1.8 0.15 11.7 1.2 1.5 1 1 0 1 1 1 0 Carlavirus putative nucleic acid binding protein NOB1_Zn_bind PF08772.6 AIN98290.1 - 0.12 12.2 3.8 0.31 10.8 0.5 2.3 1 1 1 2 2 2 0 Nin one binding (NOB1) Zn-ribbon like Zn_Tnp_IS1595 PF12760.2 AIN98290.1 - 0.14 12.0 2.5 0.22 11.3 1.7 1.3 1 0 0 1 1 1 0 Transposase zinc-ribbon domain Proteasome PF00227.21 AIN98291.1 - 1e-57 194.5 0.0 1.3e-57 194.1 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 AIN98291.1 - 2.9e-13 48.8 0.0 7.2e-13 47.5 0.0 1.7 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Pex14_N PF04695.8 AIN98292.1 - 1.3e-27 96.4 0.1 1.3e-27 96.4 0.0 3.3 2 1 2 4 4 4 1 Peroxisomal membrane anchor protein (Pex14p) conserved region Rootletin PF15035.1 AIN98292.1 - 0.00015 21.8 0.3 0.00027 20.9 0.2 1.5 1 0 0 1 1 1 1 Ciliary rootlet component, centrosome cohesion Reo_sigmaC PF04582.7 AIN98292.1 - 0.0021 17.2 0.4 0.0035 16.5 0.3 1.2 1 0 0 1 1 1 1 Reovirus sigma C capsid protein IncA PF04156.9 AIN98292.1 - 0.0031 17.1 0.1 0.0044 16.6 0.0 1.3 1 0 0 1 1 1 1 IncA protein Atg14 PF10186.4 AIN98292.1 - 0.0036 16.2 0.2 0.0053 15.7 0.2 1.1 1 0 0 1 1 1 1 UV radiation resistance protein and autophagy-related subunit 14 CUT PF02376.10 AIN98292.1 - 0.0062 16.3 0.0 0.01 15.6 0.0 1.4 1 0 0 1 1 1 1 CUT domain ERM PF00769.14 AIN98292.1 - 0.011 15.2 2.6 0.02 14.4 1.8 1.4 1 0 0 1 1 1 0 Ezrin/radixin/moesin family Spectrin PF00435.16 AIN98292.1 - 0.026 14.8 1.5 0.042 14.1 1.0 1.3 1 0 0 1 1 1 0 Spectrin repeat Siah-Interact_N PF09032.6 AIN98292.1 - 0.028 14.4 1.2 0.028 14.4 0.8 2.5 1 1 1 2 2 2 0 Siah interacting protein, N terminal BLOC1_2 PF10046.4 AIN98292.1 - 0.038 14.1 3.4 0.068 13.3 2.4 1.3 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 TMCO5 PF14992.1 AIN98292.1 - 0.056 12.5 1.3 0.082 12.0 0.9 1.2 1 0 0 1 1 1 0 TMCO5 family HOOK PF05622.7 AIN98292.1 - 0.084 10.6 3.5 0.12 10.2 2.5 1.1 1 0 0 1 1 1 0 HOOK protein Flagellin_C PF00700.16 AIN98292.1 - 0.084 13.0 1.8 0.18 11.9 1.3 1.6 1 0 0 1 1 1 0 Bacterial flagellin C-terminal helical region DUF1192 PF06698.6 AIN98292.1 - 0.094 12.5 4.3 0.078 12.8 1.5 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF1192) DASH_Dad2 PF08654.5 AIN98292.1 - 0.1 12.6 1.2 0.21 11.6 0.3 1.9 1 1 1 2 2 2 0 DASH complex subunit Dad2 DUF3573 PF12097.3 AIN98292.1 - 0.27 9.8 0.5 0.38 9.3 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) DivIC PF04977.10 AIN98292.1 - 0.85 9.1 11.6 0.1 12.0 2.7 2.5 1 1 1 2 2 2 0 Septum formation initiator HALZ PF02183.13 AIN98292.1 - 0.92 9.2 6.7 2.2 8.0 0.3 2.5 2 0 0 2 2 2 0 Homeobox associated leucine zipper DUF972 PF06156.8 AIN98292.1 - 1.5 9.2 3.7 2.8 8.3 2.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF972) XhlA PF10779.4 AIN98292.1 - 3.6 7.5 5.2 7.7 6.5 3.6 1.6 1 0 0 1 1 1 0 Haemolysin XhlA APG6 PF04111.7 AIN98292.1 - 4.5 6.2 6.1 6.7 5.6 4.2 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF883 PF05957.8 AIN98292.1 - 8 6.9 8.2 34 4.9 3.8 2.7 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) TMF_DNA_bd PF12329.3 AIN98292.1 - 9.6 6.1 15.0 0.15 11.8 1.6 2.7 2 1 1 3 3 2 0 TATA element modulatory factor 1 DNA binding OmpH PF03938.9 AIN98293.1 - 0.00058 19.8 0.0 0.0019 18.1 0.0 1.9 2 1 0 2 2 2 1 Outer membrane protein (OmpH-like) OrfB_IS605 PF01385.14 AIN98293.1 - 0.17 11.2 5.8 0.37 10.1 4.0 1.5 1 0 0 1 1 1 0 Probable transposase DUF4551 PF15087.1 AIN98293.1 - 0.64 8.3 9.8 1.1 7.5 6.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) BolA PF01722.13 AIN98294.1 - 1.4e-18 66.6 0.0 1.5e-18 66.5 0.0 1.0 1 0 0 1 1 1 1 BolA-like protein Hist_deacetyl PF00850.14 AIN98295.1 - 4.1e-76 256.2 0.2 2.3e-45 155.2 0.2 2.1 2 0 0 2 2 2 2 Histone deacetylase domain SR-25 PF10500.4 AIN98295.1 - 0.19 11.2 2.3 0.29 10.5 1.6 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein CLN3 PF02487.12 AIN98296.1 - 1.1e-23 83.6 35.9 1.2e-11 44.0 13.8 3.6 3 1 0 3 3 3 2 CLN3 protein IncA PF04156.9 AIN98296.1 - 0.22 11.0 0.0 0.22 11.0 0.0 2.3 3 0 0 3 3 3 0 IncA protein Ribosomal_L5_C PF00673.16 AIN98298.1 - 6.5e-22 77.0 0.0 1.1e-21 76.3 0.0 1.4 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.14 AIN98298.1 - 1.5e-16 59.9 0.4 5.5e-16 58.0 0.0 2.0 2 0 0 2 2 2 1 Ribosomal protein L5 SET PF00856.23 AIN98299.1 - 0.00053 20.3 0.0 0.00094 19.5 0.0 1.5 1 0 0 1 1 1 1 SET domain R3H PF01424.17 AIN98301.1 - 1.3e-10 40.8 0.1 2.6e-10 39.8 0.1 1.6 1 0 0 1 1 1 1 R3H domain zf-NF-X1 PF01422.12 AIN98301.1 - 2.7e-10 39.9 222.8 1.1e-05 25.2 9.6 15.5 16 1 0 16 16 16 9 NF-X1 type zinc finger CTDII PF01556.13 AIN98303.1 - 6e-22 77.3 0.0 4.6e-21 74.5 0.0 2.3 3 0 0 3 3 3 1 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.14 AIN98303.1 - 8.5e-12 44.9 9.0 1.8e-11 43.8 6.2 1.6 1 0 0 1 1 1 1 DnaJ central domain DUF3556 PF12077.3 AIN98303.1 - 0.044 11.8 0.1 0.054 11.5 0.0 1.2 1 0 0 1 1 1 0 Transmembrane protein of unknown function (DUF3556) HypA PF01155.14 AIN98303.1 - 0.045 13.4 2.7 0.11 12.1 1.7 1.9 2 0 0 2 2 2 0 Hydrogenase expression/synthesis hypA family DUF2777 PF10949.3 AIN98303.1 - 0.083 12.5 0.1 0.12 11.9 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2777) Herpes_UL16 PF03044.9 AIN98303.1 - 0.11 11.4 1.8 0.16 10.9 1.3 1.2 1 0 0 1 1 1 0 Herpesvirus UL16/UL94 family Lar_restr_allev PF14354.1 AIN98303.1 - 0.16 12.2 1.4 1.1 9.6 1.0 2.3 1 1 0 1 1 1 0 Restriction alleviation protein Lar Pox_MCEL PF03291.11 AIN98304.1 - 2.6e-43 148.1 0.0 3.3e-43 147.8 0.0 1.2 1 0 0 1 1 1 1 mRNA capping enzyme mRNA_cap_enzyme PF01331.14 AIN98304.1 - 2.1e-07 30.8 0.0 0.0097 15.6 0.0 2.5 2 0 0 2 2 2 2 mRNA capping enzyme, catalytic domain mRNA_cap_C PF03919.10 AIN98304.1 - 3.6e-07 30.4 0.0 9.5e-07 29.1 0.0 1.7 1 0 0 1 1 1 1 mRNA capping enzyme, C-terminal domain Methyltransf_26 PF13659.1 AIN98304.1 - 0.093 12.7 0.8 0.7 9.9 0.0 2.8 3 1 0 3 3 3 0 Methyltransferase domain GATase PF00117.23 AIN98306.1 - 1.4e-36 125.7 0.0 2.4e-36 124.9 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase class-I GMP_synt_C PF00958.17 AIN98306.1 - 6.5e-27 93.0 1.5 3.4e-26 90.7 1.0 2.3 1 1 0 1 1 1 1 GMP synthase C terminal domain Peptidase_C26 PF07722.8 AIN98306.1 - 2.1e-15 56.7 0.0 6.4e-15 55.1 0.0 1.9 1 0 0 1 1 1 1 Peptidase C26 NAD_synthase PF02540.12 AIN98306.1 - 2e-09 36.7 0.0 5.1e-05 22.2 0.0 2.3 2 0 0 2 2 2 2 NAD synthase QueC PF06508.8 AIN98306.1 - 6.6e-06 25.5 0.0 2.2e-05 23.8 0.0 1.8 1 1 0 1 1 1 1 Queuosine biosynthesis protein QueC ThiI PF02568.9 AIN98306.1 - 0.00064 19.2 0.1 0.0024 17.3 0.0 2.0 3 0 0 3 3 3 1 Thiamine biosynthesis protein (ThiI) PAPS_reduct PF01507.14 AIN98306.1 - 0.0023 17.7 0.0 0.0044 16.8 0.0 1.6 1 1 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family Asn_synthase PF00733.16 AIN98306.1 - 0.0032 16.9 0.0 0.0059 16.1 0.0 1.4 1 0 0 1 1 1 1 Asparagine synthase Arginosuc_synth PF00764.14 AIN98306.1 - 0.0034 16.4 0.0 0.0049 15.9 0.0 1.2 1 0 0 1 1 1 1 Arginosuccinate synthase ATP_bind_3 PF01171.15 AIN98306.1 - 0.0048 16.4 0.1 0.02 14.4 0.1 1.9 2 0 0 2 2 2 1 PP-loop family GATase_3 PF07685.9 AIN98306.1 - 0.0083 15.7 0.1 0.016 14.7 0.1 1.4 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain tRNA_Me_trans PF03054.11 AIN98306.1 - 0.016 13.7 0.0 0.035 12.6 0.0 1.6 2 0 0 2 2 2 0 tRNA methyl transferase Med20 PF08612.6 AIN98307.1 - 0.09 11.9 0.6 0.15 11.2 0.1 1.7 1 1 0 1 1 1 0 TATA-binding related factor (TRF) of subunit 20 of Mediator complex Hom_end_hint PF05203.11 AIN98307.1 - 0.24 11.1 8.3 0.32 10.6 5.7 1.3 1 0 0 1 1 1 0 Hom_end-associated Hint Atg14 PF10186.4 AIN98307.1 - 0.42 9.5 27.7 0.033 13.1 14.0 2.1 1 1 1 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 Imm42 PF15601.1 AIN98307.1 - 0.42 10.0 5.6 0.46 9.9 0.8 2.4 2 1 0 2 2 2 0 Immunity protein 42 Tup_N PF08581.5 AIN98307.1 - 0.46 10.7 0.1 0.46 10.7 0.1 3.2 2 2 1 3 3 3 0 Tup N-terminal DUF3584 PF12128.3 AIN98307.1 - 0.66 7.2 30.4 1.1 6.5 21.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) AKNA PF12443.3 AIN98307.1 - 1.1 9.3 10.6 0.2 11.6 2.7 2.8 2 1 0 3 3 3 0 AT-hook-containing transcription factor Mod_r PF07200.8 AIN98307.1 - 1.1 9.1 23.9 0.28 11.1 6.3 3.3 1 1 2 3 3 3 0 Modifier of rudimentary (Mod(r)) protein zf-CCCH PF00642.19 AIN98308.1 - 1.5e-06 27.7 13.3 0.0083 15.7 0.3 2.7 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) BAG PF02179.11 AIN98309.1 - 0.00097 19.1 0.0 0.0019 18.2 0.0 1.4 1 0 0 1 1 1 1 BAG domain DUF2036 PF09724.4 AIN98310.1 - 1.6e-32 112.9 0.0 2.3e-32 112.4 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2036) IL8 PF00048.15 AIN98310.1 - 0.14 12.1 0.1 0.58 10.1 0.0 2.0 2 0 0 2 2 2 0 Small cytokines (intecrine/chemokine), interleukin-8 like zf-CCCH PF00642.19 AIN98311.1 - 7.5e-06 25.5 20.1 2.5e-05 23.8 1.2 3.9 4 0 0 4 4 4 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) LRV_FeS PF05484.6 AIN98311.1 - 0.027 14.0 5.3 0.091 12.3 0.1 2.5 2 0 0 2 2 2 0 LRV protein FeS4 cluster zf-CCCH_2 PF14608.1 AIN98311.1 - 0.075 13.0 6.5 3.6 7.7 0.2 2.7 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type Apolipoprotein PF01442.13 AIN98313.1 - 9.8e-06 25.2 3.4 1.9e-05 24.3 2.4 1.5 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain DUF883 PF05957.8 AIN98313.1 - 0.0016 18.7 10.5 0.088 13.2 2.2 2.5 1 1 2 3 3 3 3 Bacterial protein of unknown function (DUF883) ApoO PF09769.4 AIN98313.1 - 0.002 17.8 2.0 0.0036 17.0 1.0 1.7 1 1 0 1 1 1 1 Apolipoprotein O ATG_C PF09333.6 AIN98313.1 - 0.0037 17.4 6.5 0.027 14.6 0.1 2.9 2 1 0 2 2 2 1 ATG C terminal domain DUF4407 PF14362.1 AIN98313.1 - 0.025 13.5 1.6 0.036 13.0 1.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) ATP-synt_B PF00430.13 AIN98313.1 - 0.037 13.8 10.1 0.13 12.0 7.0 1.9 1 1 0 1 1 1 0 ATP synthase B/B' CF(0) DUF357 PF04010.8 AIN98313.1 - 0.041 13.5 1.4 0.18 11.4 0.2 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF357) Activator-TraM PF11657.3 AIN98313.1 - 0.044 13.2 1.7 0.087 12.3 1.1 1.6 1 0 0 1 1 1 0 Transcriptional activator TraM XLF PF09302.6 AIN98313.1 - 0.046 13.4 0.0 0.052 13.3 0.0 1.2 1 0 0 1 1 1 0 XLF (XRCC4-like factor) Prominin PF05478.6 AIN98313.1 - 0.056 10.9 2.5 0.071 10.6 1.7 1.1 1 0 0 1 1 1 0 Prominin YtxH PF12732.2 AIN98313.1 - 0.061 13.6 7.7 1.8 9.0 5.3 2.3 1 1 0 1 1 1 0 YtxH-like protein KfrA_N PF11740.3 AIN98313.1 - 0.073 13.5 6.8 0.17 12.3 4.7 1.7 1 0 0 1 1 1 0 Plasmid replication region DNA-binding N-term DUF4456 PF14644.1 AIN98313.1 - 0.24 10.6 3.3 0.41 9.8 2.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4456) Use1 PF09753.4 AIN98313.1 - 0.24 10.7 5.0 0.28 10.5 3.0 1.4 1 1 0 1 1 1 0 Membrane fusion protein Use1 DivIVA PF05103.8 AIN98313.1 - 0.35 10.9 8.7 1.3 9.0 6.0 1.9 1 1 0 1 1 1 0 DivIVA protein DUF2564 PF10819.3 AIN98313.1 - 0.37 10.9 7.9 1.5 8.9 1.3 2.8 1 1 1 2 2 2 0 Protein of unknown function (DUF2564) YbaB_DNA_bd PF02575.11 AIN98313.1 - 0.41 10.5 5.1 0.26 11.1 1.3 2.2 1 1 1 2 2 2 0 YbaB/EbfC DNA-binding family Med25_SD1 PF11235.3 AIN98313.1 - 0.76 10.0 4.4 2.6 8.3 2.9 1.9 1 1 0 1 1 1 0 Mediator complex subunit 25 synapsin 1 Phasin PF05597.6 AIN98313.1 - 2 8.2 9.4 1.2e+02 2.4 6.5 2.3 1 1 0 1 1 1 0 Poly(hydroxyalcanoate) granule associated protein (phasin) Glypican PF01153.14 AIN98315.1 - 0.62 8.6 5.2 1.3 7.5 3.6 1.4 1 0 0 1 1 1 0 Glypican DUF1736 PF08409.6 AIN98316.1 - 1.2e-23 82.4 0.3 3.4e-23 80.9 0.2 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1736) TPR_11 PF13414.1 AIN98316.1 - 0.0001 21.9 2.0 0.011 15.3 0.2 2.6 1 1 0 2 2 2 2 TPR repeat TPR_17 PF13431.1 AIN98316.1 - 0.013 15.6 0.1 1.8 8.9 0.0 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF3040 PF11239.3 AIN98316.1 - 0.17 11.9 3.3 2.8 8.0 0.0 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF3040) Aa_trans PF01490.13 AIN98317.1 - 1.3e-61 208.2 37.2 1.7e-61 207.9 25.8 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.8 AIN98317.1 - 4.9e-05 22.3 12.8 4.9e-05 22.3 8.9 2.2 2 0 0 2 2 2 1 Tryptophan/tyrosine permease family TRAP_alpha PF03896.11 AIN98319.1 - 2.6e-15 56.2 0.1 3.2e-15 55.8 0.1 1.2 1 0 0 1 1 1 1 Translocon-associated protein (TRAP), alpha subunit Wzt_C PF14524.1 AIN98319.1 - 0.019 14.6 0.0 0.053 13.2 0.0 1.6 1 1 0 1 1 1 0 Wzt C-terminal domain Lep_receptor_Ig PF06328.6 AIN98319.1 - 0.12 12.2 0.0 0.22 11.4 0.0 1.4 1 0 0 1 1 1 0 Ig-like C2-type domain zf-Tim10_DDP PF02953.10 AIN98320.1 - 3e-11 42.4 3.3 3.2e-11 42.3 2.3 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger DUF842 PF05811.8 AIN98320.1 - 0.0058 16.0 0.7 0.0067 15.8 0.5 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF842) Mito_carr PF00153.22 AIN98323.1 - 4.1e-11 42.4 1.4 1.3e-08 34.3 0.1 3.6 4 0 0 4 4 4 2 Mitochondrial carrier protein DUF2618 PF10940.3 AIN98324.1 - 0.077 12.7 0.4 0.16 11.7 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2618) Carn_acyltransf PF00755.15 AIN98325.1 - 3.9e-73 246.4 0.0 9.8e-73 245.1 0.0 1.6 1 1 0 1 1 1 1 Choline/Carnitine o-acyltransferase SEP PF08059.8 AIN98326.1 - 2.8e-19 69.2 0.1 8.9e-19 67.5 0.0 1.9 2 0 0 2 2 2 1 SEP domain CUE PF02845.11 AIN98326.1 - 0.0042 16.5 0.0 0.01 15.3 0.0 1.6 1 0 0 1 1 1 1 CUE domain UBA_4 PF14555.1 AIN98326.1 - 0.029 13.8 0.2 0.066 12.7 0.1 1.5 1 0 0 1 1 1 0 UBA-like domain APG6 PF04111.7 AIN98328.1 - 0.012 14.6 4.2 0.017 14.1 2.9 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 Baculo_PEP_C PF04513.7 AIN98328.1 - 0.037 13.8 0.7 0.064 13.0 0.5 1.4 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF4061 PF13270.1 AIN98328.1 - 0.079 13.0 4.0 0.2 11.7 1.7 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4061) Poty_PP PF08440.5 AIN98328.1 - 0.08 11.9 0.4 0.11 11.5 0.3 1.1 1 0 0 1 1 1 0 Potyviridae polyprotein Macoilin PF09726.4 AIN98328.1 - 0.12 10.6 6.4 0.15 10.3 4.5 1.0 1 0 0 1 1 1 0 Transmembrane protein FUSC PF04632.7 AIN98328.1 - 0.12 10.7 8.5 0.14 10.5 5.9 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family Hanta_nucleocap PF00846.13 AIN98328.1 - 0.22 10.2 0.9 0.32 9.6 0.6 1.2 1 0 0 1 1 1 0 Hantavirus nucleocapsid protein Occludin_ELL PF07303.8 AIN98328.1 - 0.65 10.7 2.9 0.95 10.2 1.2 1.8 1 1 1 2 2 2 0 Occludin homology domain MscS_porin PF12795.2 AIN98328.1 - 0.66 9.2 14.3 0.87 8.8 9.9 1.1 1 0 0 1 1 1 0 Mechanosensitive ion channel porin domain ALMT PF11744.3 AIN98328.1 - 0.78 8.3 3.2 1 7.9 2.2 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter Peptidase_S46 PF10459.4 AIN98328.1 - 0.91 7.8 7.0 1.2 7.4 4.9 1.0 1 0 0 1 1 1 0 Peptidase S46 NifQ PF04891.7 AIN98328.1 - 1.2 9.2 6.1 2.3 8.3 4.1 1.6 1 1 0 1 1 1 0 NifQ DivIVA PF05103.8 AIN98328.1 - 6.6 6.8 10.2 9 6.3 7.1 1.2 1 0 0 1 1 1 0 DivIVA protein OPA3 PF07047.7 AIN98329.1 - 0.0049 16.6 1.2 0.0084 15.8 0.8 1.3 1 0 0 1 1 1 1 Optic atrophy 3 protein (OPA3) DNA_primase_S PF01896.14 AIN98332.1 - 3.6e-37 127.3 0.1 5.6e-37 126.7 0.1 1.2 1 0 0 1 1 1 1 Eukaryotic and archaeal DNA primase small subunit cNMP_binding PF00027.24 AIN98333.1 - 1.3e-06 28.1 0.0 0.00073 19.3 0.0 2.9 3 0 0 3 3 3 2 Cyclic nucleotide-binding domain GCC2_GCC3 PF07699.8 AIN98334.1 - 4e-05 23.1 64.3 0.00026 20.4 1.6 8.9 6 3 3 9 9 9 6 GCC2 and GCC3 Ribosomal_S19 PF00203.16 AIN98335.1 - 4.6e-26 90.2 0.1 7.9e-26 89.4 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein S19 PmbA_TldD PF01523.11 AIN98335.1 - 0.0082 15.4 0.0 0.0091 15.3 0.0 1.2 1 0 0 1 1 1 1 Putative modulator of DNA gyrase Acetyltransf_1 PF00583.19 AIN98337.1 - 6.2e-12 45.3 0.0 9.8e-12 44.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 AIN98337.1 - 1.2e-06 28.5 0.0 2.2e-06 27.7 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 AIN98337.1 - 0.00014 21.9 0.1 0.00046 20.2 0.0 1.9 3 0 0 3 3 3 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 AIN98337.1 - 0.00019 21.1 0.0 0.00035 20.2 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_8 PF13523.1 AIN98337.1 - 0.013 15.3 0.0 0.026 14.3 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Ribosomal_S19 PF00203.16 AIN98338.1 - 4.6e-26 90.2 0.1 7.9e-26 89.4 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein S19 PmbA_TldD PF01523.11 AIN98338.1 - 0.0082 15.4 0.0 0.0091 15.3 0.0 1.2 1 0 0 1 1 1 1 Putative modulator of DNA gyrase tRNA_bind PF01588.15 AIN98339.1 - 3.4e-26 90.8 0.0 6.3e-26 90.0 0.0 1.5 1 0 0 1 1 1 1 Putative tRNA binding domain Dynamin_N PF00350.18 AIN98340.1 - 3.3e-14 53.0 0.0 1.3e-13 51.1 0.0 1.9 1 1 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.18 AIN98340.1 - 1.5e-10 40.9 0.0 3.4e-10 39.8 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.11 AIN98340.1 - 0.0013 17.9 0.1 0.0074 15.4 0.1 2.1 1 1 0 1 1 1 1 Protein of unknown function, DUF258 Miro PF08477.8 AIN98340.1 - 0.0023 18.4 0.0 0.19 12.2 0.0 2.4 1 1 0 1 1 1 1 Miro-like protein FeoB_N PF02421.13 AIN98340.1 - 0.003 16.8 0.0 0.26 10.5 0.0 2.7 2 1 0 2 2 2 1 Ferrous iron transport protein B GTP_EFTU PF00009.22 AIN98340.1 - 0.0083 15.5 0.0 1.1 8.6 0.0 2.6 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain Nup153 PF08604.5 AIN98340.1 - 0.036 12.7 0.0 0.054 12.1 0.0 1.2 1 0 0 1 1 1 0 Nucleoporin Nup153-like ABC_tran PF00005.22 AIN98340.1 - 0.041 14.1 0.0 0.085 13.1 0.0 1.5 1 0 0 1 1 1 0 ABC transporter Lysine_decarbox PF03641.9 AIN98340.1 - 0.051 13.3 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 Possible lysine decarboxylase AAA_29 PF13555.1 AIN98340.1 - 0.1 12.1 0.0 0.24 10.9 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Pkinase PF00069.20 AIN98341.1 - 9.4e-46 156.0 0.0 7.1e-36 123.6 0.0 4.0 2 2 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 AIN98341.1 - 2.8e-20 72.4 0.0 4e-17 62.1 0.0 3.0 3 1 0 3 3 3 2 Protein tyrosine kinase Kdo PF06293.9 AIN98341.1 - 8.4e-05 21.7 0.1 0.00014 21.0 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 AIN98341.1 - 0.00015 21.5 0.2 0.00015 21.5 0.1 2.0 2 0 0 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 AIN98341.1 - 0.02 14.4 0.0 0.034 13.7 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase Med26 PF08711.6 AIN98342.1 - 2.9e-07 29.8 4.0 4.3e-05 22.9 0.0 3.4 3 0 0 3 3 3 3 TFIIS helical bundle-like domain RabGAP-TBC PF00566.13 AIN98344.1 - 3e-31 108.5 0.0 4.3e-31 108.0 0.0 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain FHA PF00498.21 AIN98345.1 - 9.5e-15 54.4 0.0 1.5e-14 53.8 0.0 1.3 1 0 0 1 1 1 1 FHA domain Rotamase PF00639.16 AIN98345.1 - 6.6e-12 46.0 0.0 1.4e-11 44.9 0.0 1.6 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_3 PF13616.1 AIN98345.1 - 1.3e-06 28.6 0.0 2.2e-06 27.9 0.0 1.4 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_2 PF13145.1 AIN98345.1 - 0.0032 18.0 0.4 0.011 16.4 0.0 2.0 3 0 0 3 3 3 1 PPIC-type PPIASE domain DUF3439 PF11921.3 AIN98345.1 - 0.014 15.1 1.4 0.026 14.2 1.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) TPR_16 PF13432.1 AIN98346.1 - 0.00066 20.2 2.2 0.00066 20.2 1.5 3.0 3 0 0 3 3 3 1 Tetratricopeptide repeat PPR PF01535.15 AIN98346.1 - 0.0082 16.0 0.0 15 5.8 0.0 4.1 3 0 0 3 3 3 2 PPR repeat Kinesin PF00225.18 AIN98347.1 - 1.9e-84 283.2 6.6 6.5e-48 163.1 0.1 3.1 3 0 0 3 3 3 2 Kinesin motor domain AAA_33 PF13671.1 AIN98347.1 - 0.0011 18.9 0.0 0.0068 16.2 0.0 2.5 1 0 0 1 1 1 1 AAA domain TPR_MLP1_2 PF07926.7 AIN98347.1 - 0.0022 17.7 15.6 0.0022 17.7 10.8 4.5 2 1 2 4 4 4 1 TPR/MLP1/MLP2-like protein DivIC PF04977.10 AIN98347.1 - 0.043 13.3 0.3 0.043 13.3 0.2 5.7 2 1 4 6 6 6 0 Septum formation initiator AAA PF00004.24 AIN98348.1 - 1.5e-43 148.1 0.0 3e-43 147.1 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 AIN98348.1 - 7.7e-07 29.3 0.0 0.00056 20.0 0.0 2.5 1 1 1 2 2 2 2 AAA domain AAA_5 PF07728.9 AIN98348.1 - 1.5e-06 27.9 0.1 3.2e-05 23.6 0.0 2.5 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 AIN98348.1 - 1.4e-05 25.1 0.0 8.4e-05 22.6 0.0 2.1 2 1 1 3 3 3 1 AAA ATPase domain AAA_2 PF07724.9 AIN98348.1 - 1.7e-05 24.7 0.0 4e-05 23.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_17 PF13207.1 AIN98348.1 - 0.00015 22.5 1.3 0.00031 21.5 0.2 2.2 2 1 0 2 2 2 1 AAA domain DUF815 PF05673.8 AIN98348.1 - 0.00019 20.4 0.0 0.00033 19.6 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) RuvB_N PF05496.7 AIN98348.1 - 0.00033 19.7 0.0 0.00064 18.8 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus Arch_ATPase PF01637.13 AIN98348.1 - 0.00061 19.5 0.0 0.27 10.9 0.0 2.7 2 1 1 3 3 3 1 Archaeal ATPase AAA_19 PF13245.1 AIN98348.1 - 0.0007 19.3 0.1 0.0015 18.2 0.1 1.5 1 0 0 1 1 1 1 Part of AAA domain AAA_14 PF13173.1 AIN98348.1 - 0.0011 18.8 0.0 0.0025 17.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.1 AIN98348.1 - 0.0013 18.6 0.0 0.0023 17.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 AIN98348.1 - 0.0024 17.0 0.0 0.0043 16.1 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin AAA_33 PF13671.1 AIN98348.1 - 0.0024 17.7 0.0 0.0047 16.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.12 AIN98348.1 - 0.0029 17.0 0.0 0.005 16.2 0.0 1.3 1 0 0 1 1 1 1 IstB-like ATP binding protein RNA_helicase PF00910.17 AIN98348.1 - 0.0069 16.5 0.0 0.017 15.3 0.0 1.6 1 0 0 1 1 1 1 RNA helicase Mg_chelatase PF01078.16 AIN98348.1 - 0.0072 15.5 0.0 0.019 14.1 0.0 1.6 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_24 PF13479.1 AIN98348.1 - 0.0079 15.7 0.1 0.017 14.6 0.1 1.5 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 AIN98348.1 - 0.0091 16.3 0.6 0.022 15.0 0.0 2.0 2 1 0 2 2 2 1 AAA domain AAA_3 PF07726.6 AIN98348.1 - 0.0092 15.5 0.0 0.022 14.3 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) TIP49 PF06068.8 AIN98348.1 - 0.0095 14.6 0.0 0.016 13.9 0.0 1.3 1 0 0 1 1 1 1 TIP49 C-terminus AAA_25 PF13481.1 AIN98348.1 - 0.023 14.0 0.8 0.14 11.5 0.1 2.1 1 1 0 2 2 2 0 AAA domain NTPase_1 PF03266.10 AIN98348.1 - 0.031 13.9 0.1 0.064 12.9 0.0 1.6 1 0 0 1 1 1 0 NTPase Sigma54_activat PF00158.21 AIN98348.1 - 0.049 13.0 0.0 0.14 11.5 0.0 1.8 2 0 0 2 2 1 0 Sigma-54 interaction domain PhoH PF02562.11 AIN98348.1 - 0.064 12.4 0.2 0.15 11.2 0.1 1.6 1 1 0 1 1 1 0 PhoH-like protein Parvo_NS1 PF01057.12 AIN98348.1 - 0.067 12.0 0.0 0.12 11.2 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 NB-ARC PF00931.17 AIN98348.1 - 0.09 11.6 0.0 0.17 10.7 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain Histone PF00125.19 AIN98348.1 - 0.12 12.5 0.0 0.53 10.4 0.0 2.2 2 0 0 2 2 1 0 Core histone H2A/H2B/H3/H4 Rer1 PF03248.8 AIN98349.1 - 7.6e-59 198.2 4.2 9.4e-59 197.9 2.9 1.0 1 0 0 1 1 1 1 Rer1 family DmsC PF04976.7 AIN98349.1 - 0.0023 17.2 0.7 0.0035 16.6 0.5 1.3 1 1 0 1 1 1 1 DMSO reductase anchor subunit (DmsC) UPF0066 PF01980.11 AIN98350.1 - 3.9e-28 97.8 0.0 7.8e-24 83.9 0.0 2.4 2 0 0 2 2 2 2 Uncharacterised protein family UPF0066 PWWP PF00855.12 AIN98350.1 - 4.8e-05 23.4 0.6 0.00012 22.1 0.4 1.9 1 1 0 1 1 1 1 PWWP domain AMOP PF03782.12 AIN98350.1 - 0.028 14.4 0.1 0.12 12.3 0.0 2.0 3 0 0 3 3 3 0 AMOP domain BCL9 PF11502.3 AIN98350.1 - 3.9 7.0 7.4 1.1 8.8 2.7 1.9 2 0 0 2 2 2 0 B-cell lymphoma 9 protein Acetyltransf_3 PF13302.1 AIN98351.1 - 4.4e-11 43.1 0.3 7.8e-08 32.5 0.0 3.1 3 1 0 3 3 3 2 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 AIN98351.1 - 4.8e-07 29.7 0.0 1.6e-05 24.8 0.0 2.3 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_8 PF13523.1 AIN98351.1 - 1.7e-05 24.7 0.1 0.00013 21.8 0.0 2.2 2 1 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 AIN98351.1 - 0.011 15.6 0.0 0.044 13.7 0.0 1.8 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain FR47 PF08445.5 AIN98351.1 - 0.16 11.6 0.0 0.38 10.5 0.0 1.5 1 0 0 1 1 1 0 FR47-like protein UQ_con PF00179.21 AIN98352.1 - 5.9e-42 142.4 0.0 8.8e-42 141.8 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 AIN98352.1 - 0.00018 21.2 0.0 0.00026 20.7 0.0 1.4 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 AIN98352.1 - 0.13 12.1 0.0 0.18 11.7 0.0 1.4 1 1 0 1 1 1 0 RWD domain AAA PF00004.24 AIN98353.1 - 2.8e-38 131.0 0.3 7.9e-38 129.6 0.0 1.9 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 AIN98353.1 - 1.8e-05 24.4 0.1 0.00017 21.3 0.0 2.6 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 AIN98353.1 - 3.2e-05 23.9 1.3 0.0085 16.0 0.0 3.0 2 1 1 3 3 3 1 AAA ATPase domain AAA_2 PF07724.9 AIN98353.1 - 0.00031 20.6 0.1 0.0033 17.3 0.0 2.5 2 1 0 2 2 2 1 AAA domain (Cdc48 subfamily) RuvB_N PF05496.7 AIN98353.1 - 0.00032 19.8 0.0 0.001 18.1 0.0 1.8 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus DUF815 PF05673.8 AIN98353.1 - 0.0015 17.4 0.4 0.0034 16.3 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_22 PF13401.1 AIN98353.1 - 0.002 18.2 2.3 0.053 13.6 0.1 2.8 2 1 1 3 3 3 1 AAA domain AAA_33 PF13671.1 AIN98353.1 - 0.0037 17.1 0.4 0.041 13.7 0.0 2.5 2 0 0 2 2 2 1 AAA domain Mg_chelatase PF01078.16 AIN98353.1 - 0.0064 15.6 0.0 0.016 14.4 0.0 1.6 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_19 PF13245.1 AIN98353.1 - 0.0068 16.1 0.2 0.02 14.6 0.1 1.8 1 0 0 1 1 1 1 Part of AAA domain Zeta_toxin PF06414.7 AIN98353.1 - 0.017 14.2 0.0 0.017 14.2 0.0 2.1 2 0 0 2 2 2 0 Zeta toxin IstB_IS21 PF01695.12 AIN98353.1 - 0.017 14.5 0.6 0.041 13.3 0.0 1.8 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_25 PF13481.1 AIN98353.1 - 0.036 13.4 0.3 0.036 13.4 0.2 2.9 2 1 0 3 3 3 0 AAA domain KaiC PF06745.8 AIN98353.1 - 0.045 12.8 0.1 0.12 11.4 0.0 1.7 2 0 0 2 2 2 0 KaiC PhoH PF02562.11 AIN98353.1 - 0.046 12.9 0.0 0.21 10.8 0.0 2.0 2 0 0 2 2 2 0 PhoH-like protein NACHT PF05729.7 AIN98353.1 - 0.061 12.9 0.2 0.64 9.6 0.0 2.4 2 0 0 2 2 2 0 NACHT domain Sigma54_activat PF00158.21 AIN98353.1 - 0.066 12.6 0.0 0.38 10.2 0.0 2.1 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_24 PF13479.1 AIN98353.1 - 0.08 12.5 0.1 0.2 11.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.1 AIN98353.1 - 0.13 13.0 0.1 0.13 13.0 0.1 2.6 2 2 0 2 2 2 0 AAA domain ABC1 PF03109.11 AIN98354.1 - 0.17 11.8 0.5 0.33 10.9 0.3 1.4 1 0 0 1 1 1 0 ABC1 family Prefoldin PF02996.12 AIN98357.1 - 2.9e-19 68.8 3.7 4.3e-19 68.3 1.8 1.7 1 1 1 2 2 2 1 Prefoldin subunit Prefoldin_2 PF01920.15 AIN98357.1 - 0.0052 16.5 1.8 0.053 13.2 1.2 2.1 2 0 0 2 2 2 1 Prefoldin subunit Sec20 PF03908.8 AIN98357.1 - 0.048 13.3 2.3 10 5.8 1.0 2.5 2 1 1 3 3 3 0 Sec20 THF_DHG_CYH_C PF02882.14 AIN98357.1 - 0.055 12.5 0.1 0.09 11.8 0.0 1.4 1 1 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Prefoldin_3 PF13758.1 AIN98357.1 - 0.065 13.0 1.4 0.13 12.0 0.4 2.0 1 1 1 2 2 2 0 Prefoldin subunit DUF1454 PF07305.7 AIN98358.1 - 0.12 11.4 0.0 0.18 10.8 0.0 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1454) zf-CCCH PF00642.19 AIN98359.1 - 0.0039 16.8 0.9 0.0039 16.8 0.6 2.5 2 0 0 2 2 2 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.1 AIN98359.1 - 0.24 11.4 8.8 0.54 10.3 0.6 3.5 3 0 0 3 3 3 0 Zinc finger C-x8-C-x5-C-x3-H type NAD_binding_1 PF00175.16 AIN98362.1 - 7.6e-24 84.3 0.0 1.2e-23 83.7 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 AIN98362.1 - 1e-23 83.3 0.0 1.8e-23 82.5 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.7 AIN98362.1 - 2e-05 24.5 0.2 0.00029 20.7 0.0 2.2 1 1 0 2 2 2 1 Ferric reductase NAD binding domain FAD_binding_9 PF08021.6 AIN98362.1 - 0.02 14.8 0.0 0.031 14.2 0.0 1.3 1 0 0 1 1 1 0 Siderophore-interacting FAD-binding domain GreA_GreB PF01272.14 AIN98362.1 - 0.14 11.8 0.0 0.33 10.7 0.0 1.7 1 0 0 1 1 1 0 Transcription elongation factor, GreA/GreB, C-term NAD_binding_1 PF00175.16 AIN98363.1 - 1.4e-24 86.7 0.0 2e-24 86.2 0.0 1.2 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 AIN98363.1 - 5.4e-19 68.1 0.0 7.9e-19 67.6 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.7 AIN98363.1 - 6.8e-07 29.3 0.0 4.3e-06 26.7 0.0 1.9 2 0 0 2 2 2 1 Ferric reductase NAD binding domain SUI1 PF01253.17 AIN98364.1 - 7.1e-17 60.9 0.0 9.3e-16 57.4 0.0 2.7 3 0 0 3 3 3 1 Translation initiation factor SUI1 PUA PF01472.15 AIN98364.1 - 0.0078 15.9 0.2 0.033 13.9 0.0 2.2 2 0 0 2 2 2 1 PUA domain POT1 PF02765.12 AIN98364.1 - 0.058 13.3 0.6 1.4 8.7 0.0 3.1 4 0 0 4 4 4 0 Telomeric single stranded DNA binding POT1/CDC13 DUF2296 PF10058.4 AIN98365.1 - 0.0097 15.6 0.3 0.0097 15.6 0.2 3.6 2 1 2 4 4 4 1 Predicted integral membrane metal-binding protein (DUF2296) Mu-like_Com PF10122.4 AIN98365.1 - 0.024 13.6 12.4 0.056 12.5 0.4 3.6 3 2 0 3 3 3 0 Mu-like prophage protein Com Cytochrom_CIII PF02085.11 AIN98365.1 - 0.063 13.3 8.7 0.086 12.9 5.3 1.8 1 1 0 1 1 1 0 Class III cytochrome C family Cytochrom_c3_2 PF14537.1 AIN98365.1 - 0.13 12.5 12.6 0.046 14.0 5.4 2.3 1 1 1 2 2 2 0 Cytochrome c3 DZR PF12773.2 AIN98365.1 - 0.3 10.9 13.7 17 5.3 3.9 3.7 1 1 2 3 3 3 0 Double zinc ribbon Cytochrome_C7 PF14522.1 AIN98365.1 - 0.51 10.0 12.6 0.056 13.0 3.5 2.8 1 1 1 2 2 2 0 Cytochrome c7 C1_4 PF07975.7 AIN98365.1 - 3.4 7.7 11.1 12 6.0 1.6 3.3 3 0 0 3 3 3 0 TFIIH C1-like domain FYVE_2 PF02318.11 AIN98365.1 - 5.4 6.9 7.7 0.38 10.6 1.5 1.9 2 0 0 2 2 2 0 FYVE-type zinc finger Pkinase PF00069.20 AIN98366.1 - 1.5e-64 217.7 0.0 1.8e-64 217.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AIN98366.1 - 7.5e-33 113.6 0.0 1e-32 113.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 AIN98366.1 - 3.6e-06 26.1 0.0 5e-06 25.6 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 AIN98366.1 - 0.068 12.8 0.0 2.1 8.0 0.0 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family HNH_3 PF13392.1 AIN98366.1 - 0.096 12.0 0.1 0.21 11.0 0.1 1.4 1 0 0 1 1 1 0 HNH endonuclease Macoilin PF09726.4 AIN98366.1 - 1.4 7.1 5.3 2 6.6 3.7 1.1 1 0 0 1 1 1 0 Transmembrane protein MMR_HSR1 PF01926.18 AIN98367.1 - 4.9e-16 58.7 0.0 1.3e-15 57.3 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.18 AIN98367.1 - 9.2e-09 35.3 0.0 2.1e-06 27.6 0.0 2.3 1 1 1 2 2 2 2 Dynamin family GTP_EFTU PF00009.22 AIN98367.1 - 0.00011 21.6 0.0 0.0011 18.4 0.0 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Miro PF08477.8 AIN98367.1 - 0.00097 19.6 0.0 0.0055 17.2 0.0 2.2 1 1 0 1 1 1 1 Miro-like protein AIG1 PF04548.11 AIN98367.1 - 0.0047 16.0 0.0 0.019 14.0 0.0 1.9 1 1 0 1 1 1 1 AIG1 family DUF258 PF03193.11 AIN98367.1 - 0.0067 15.6 0.0 0.016 14.4 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Septin PF00735.13 AIN98367.1 - 0.016 14.2 0.0 0.027 13.4 0.0 1.3 1 0 0 1 1 1 0 Septin ABC_tran PF00005.22 AIN98367.1 - 0.018 15.3 0.0 0.04 14.2 0.0 1.5 1 0 0 1 1 1 0 ABC transporter FeoB_N PF02421.13 AIN98367.1 - 0.04 13.1 0.0 0.11 11.7 0.0 1.8 1 1 0 1 1 1 0 Ferrous iron transport protein B cobW PF02492.14 AIN98367.1 - 0.25 10.7 0.0 6.9 6.0 0.0 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain YbaB_DNA_bd PF02575.11 AIN98368.1 - 1.5e-05 24.7 0.0 3.1e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 YbaB/EbfC DNA-binding family HIF-1 PF11413.3 AIN98368.1 - 0.024 13.8 0.0 0.047 12.8 0.0 1.4 1 0 0 1 1 1 0 Hypoxia-inducible factor-1 DUF3184 PF11380.3 AIN98369.1 - 4.3e-96 322.4 25.6 1.4e-54 185.2 6.5 4.9 2 2 1 3 3 3 3 Protein of unknown function (DUF3184) Ribosomal_L22 PF00237.14 AIN98370.1 - 2.2e-13 50.0 0.0 3.3e-13 49.4 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e IQ PF00612.22 AIN98373.1 - 0.016 14.7 2.4 0.054 13.1 1.7 1.9 1 0 0 1 1 1 0 IQ calmodulin-binding motif Herpes_LMP2 PF07415.6 AIN98373.1 - 0.039 12.5 2.2 0.067 11.7 1.5 1.3 1 0 0 1 1 1 0 Gammaherpesvirus latent membrane protein (LMP2) protein Prp18 PF02840.10 AIN98374.1 - 4.6e-11 42.7 0.1 9.6e-11 41.6 0.0 1.5 1 0 0 1 1 1 1 Prp18 domain Arrestin_N PF00339.24 AIN98375.1 - 1.1e-12 48.0 0.0 2.1e-12 47.1 0.0 1.5 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.17 AIN98375.1 - 0.0012 18.9 0.0 0.21 11.7 0.0 2.4 2 0 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain LDB19 PF13002.2 AIN98375.1 - 0.022 14.2 0.0 0.04 13.4 0.0 1.4 1 0 0 1 1 1 0 Arrestin_N terminal like EF-hand_6 PF13405.1 AIN98376.1 - 5.1e-08 32.1 0.4 0.066 13.1 0.0 3.5 3 0 0 3 3 3 3 EF-hand domain EF-hand_7 PF13499.1 AIN98376.1 - 1.1e-07 31.8 0.0 3.6e-05 23.8 0.0 2.5 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.1 AIN98376.1 - 1.5e-06 27.7 0.1 0.21 11.2 0.0 3.6 4 0 0 4 4 4 2 EF-hand domain pair EF-hand_1 PF00036.27 AIN98376.1 - 0.00097 18.2 0.0 1.1 8.6 0.0 3.3 3 0 0 3 3 3 1 EF hand AAA PF00004.24 AIN98377.1 - 1.5e-13 51.1 0.0 1.1e-07 32.0 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 AIN98377.1 - 3e-05 23.7 0.0 7e-05 22.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Pkinase PF00069.20 AIN98378.1 - 5.1e-63 212.6 0.0 5.9e-63 212.4 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AIN98378.1 - 1.1e-42 145.9 0.0 1.3e-42 145.6 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 AIN98378.1 - 2.8e-07 29.7 0.0 5.2e-07 28.9 0.0 1.4 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 AIN98378.1 - 0.0039 16.2 0.1 0.048 12.7 0.0 2.1 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinesin PF00225.18 AIN98379.1 - 8.3e-91 304.1 0.0 3e-90 302.3 0.0 2.0 1 0 0 1 1 1 1 Kinesin motor domain DUF904 PF06005.7 AIN98379.1 - 0.015 15.5 0.9 0.015 15.5 0.6 9.8 7 4 0 7 7 7 0 Protein of unknown function (DUF904) NPR2 PF06218.6 AIN98380.1 - 0.002 16.9 0.0 0.029 13.0 0.0 2.1 2 0 0 2 2 2 2 Nitrogen permease regulator 2 WD40 PF00400.27 AIN98381.1 - 0.0019 18.0 0.0 0.064 13.1 0.0 2.8 2 0 0 2 2 2 1 WD domain, G-beta repeat MRJP PF03022.11 AIN98381.1 - 0.041 13.0 0.0 0.068 12.3 0.0 1.2 1 0 0 1 1 1 0 Major royal jelly protein UAA PF08449.6 AIN98384.1 - 8.1e-42 143.1 13.3 1.3e-39 135.9 6.9 3.3 2 1 0 2 2 2 2 UAA transporter family EamA PF00892.15 AIN98384.1 - 0.015 15.3 10.8 1.3 9.0 2.3 3.5 3 0 0 3 3 3 0 EamA-like transporter family Kelch_4 PF13418.1 AIN98386.1 - 4.6e-20 71.1 15.3 4.4e-06 26.3 0.0 6.6 6 1 0 6 6 6 4 Galactose oxidase, central domain Kelch_3 PF13415.1 AIN98386.1 - 1.1e-17 63.6 26.6 8.5e-06 25.7 0.1 8.7 8 1 0 8 8 8 4 Galactose oxidase, central domain Kelch_5 PF13854.1 AIN98386.1 - 2e-17 62.7 1.3 0.00039 20.3 0.0 7.1 7 0 0 7 7 7 3 Kelch motif Kelch_6 PF13964.1 AIN98386.1 - 3.9e-15 55.2 4.4 0.039 14.1 0.0 6.5 5 1 0 5 5 5 4 Kelch motif Kelch_2 PF07646.10 AIN98386.1 - 4.8e-15 54.6 4.4 0.00011 21.8 0.0 6.5 7 0 0 7 7 7 3 Kelch motif Kelch_1 PF01344.20 AIN98386.1 - 5.7e-15 54.5 5.2 0.15 11.5 0.0 7.0 6 1 0 6 6 6 5 Kelch motif BTB PF00651.26 AIN98386.1 - 0.0075 16.2 0.0 0.12 12.3 0.0 2.7 3 0 0 3 3 3 1 BTB/POZ domain MFS_1 PF07690.11 AIN98388.1 - 8.6e-22 77.3 26.7 8.6e-22 77.3 18.5 2.3 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 AIN98388.1 - 1.5e-15 56.7 6.4 1.5e-15 56.7 4.4 2.1 2 0 0 2 2 2 2 Sugar (and other) transporter OATP PF03137.15 AIN98388.1 - 3.8e-11 41.7 13.6 6.1e-06 24.5 0.9 4.0 2 2 2 4 4 4 3 Organic Anion Transporter Polypeptide (OATP) family LSM PF01423.17 AIN98389.1 - 2.6e-13 49.3 0.1 3.2e-13 48.9 0.1 1.1 1 0 0 1 1 1 1 LSM domain Med20 PF08612.6 AIN98389.1 - 0.029 13.5 0.0 0.03 13.4 0.0 1.1 1 0 0 1 1 1 0 TATA-binding related factor (TRF) of subunit 20 of Mediator complex DUF2782 PF11191.3 AIN98389.1 - 0.073 13.0 0.0 0.083 12.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2782) Tmpp129 PF10272.4 AIN98390.1 - 3 6.4 4.4 4.7 5.8 3.1 1.2 1 0 0 1 1 1 0 Putative transmembrane protein precursor CRAL_TRIO PF00650.15 AIN98392.1 - 1.1e-13 50.9 0.0 1.4e-12 47.3 0.0 2.5 2 1 0 2 2 2 1 CRAL/TRIO domain Cohesin_HEAT PF12765.2 AIN98392.1 - 0.02 14.8 0.1 0.04 13.8 0.1 1.5 1 0 0 1 1 1 0 HEAT repeat associated with sister chromatid cohesion zf-C3HC4_3 PF13920.1 AIN98393.1 - 8.6e-09 34.9 10.9 8.6e-09 34.9 7.5 1.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 AIN98393.1 - 0.82 9.4 14.3 0.61 9.8 7.6 2.3 2 0 0 2 2 2 0 zinc-RING finger domain Dynein_heavy PF03028.10 AIN98394.1 - 8e-89 298.5 0.0 2.2e-88 297.1 0.0 1.7 1 0 0 1 1 1 1 Dynein heavy chain and region D6 of dynein motor DHC_N2 PF08393.8 AIN98394.1 - 6.5e-84 281.7 0.0 2e-83 280.1 0.0 1.9 2 0 0 2 2 2 1 Dynein heavy chain, N-terminal region 2 AAA_6 PF12774.2 AIN98394.1 - 2.4e-82 275.9 0.0 6.9e-82 274.4 0.0 1.8 1 0 0 1 1 1 1 Hydrolytic ATP binding site of dynein motor region D1 AAA_9 PF12781.2 AIN98394.1 - 3.8e-39 133.8 0.0 7.3e-39 132.9 0.0 1.4 1 0 0 1 1 1 1 ATP-binding dynein motor region D5 MT PF12777.2 AIN98394.1 - 1.5e-35 122.5 0.9 2.5e-35 121.8 0.6 1.4 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_8 PF12780.2 AIN98394.1 - 4.8e-34 117.5 0.0 3.3e-24 85.3 0.0 2.6 2 0 0 2 2 2 2 P-loop containing dynein motor region D4 AAA_5 PF07728.9 AIN98394.1 - 3.4e-30 104.5 1.0 3.5e-10 39.7 0.0 7.2 5 2 0 5 5 5 4 AAA domain (dynein-related subfamily) AAA PF00004.24 AIN98394.1 - 7.9e-20 71.3 0.0 2e-06 28.0 0.0 5.1 4 0 0 4 4 4 3 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.2 AIN98394.1 - 8.2e-19 67.7 0.0 4.2e-18 65.4 0.0 2.3 2 0 0 2 2 2 1 P-loop containing dynein motor region D3 AAA_22 PF13401.1 AIN98394.1 - 6.9e-16 58.5 6.4 1.1e-05 25.6 0.0 7.1 6 0 0 6 6 5 3 AAA domain AAA_16 PF13191.1 AIN98394.1 - 7.8e-11 42.3 21.9 0.037 14.0 0.0 7.9 8 1 1 9 9 6 4 AAA ATPase domain AAA_17 PF13207.1 AIN98394.1 - 5.2e-09 36.9 0.0 1.6 9.6 0.0 5.3 4 0 0 4 4 4 2 AAA domain FtsK_SpoIIIE PF01580.13 AIN98394.1 - 4.9e-07 29.4 1.2 0.093 12.1 0.0 4.4 4 0 0 4 4 4 2 FtsK/SpoIIIE family AAA_25 PF13481.1 AIN98394.1 - 1.2e-06 28.1 0.9 0.38 10.1 0.1 4.2 4 0 0 4 4 3 2 AAA domain AAA_14 PF13173.1 AIN98394.1 - 1.2e-06 28.4 0.0 3.3 7.6 0.0 5.2 5 0 0 5 5 5 1 AAA domain DHC_N1 PF08385.7 AIN98394.1 - 1.9e-06 26.5 3.3 0.0021 16.5 0.1 4.5 4 0 0 4 4 4 1 Dynein heavy chain, N-terminal region 1 AAA_18 PF13238.1 AIN98394.1 - 3.1e-06 27.4 0.0 3 8.1 0.0 5.0 4 0 0 4 4 4 1 AAA domain AAA_33 PF13671.1 AIN98394.1 - 1.9e-05 24.5 9.6 0.16 11.8 0.0 5.4 6 0 0 6 6 5 2 AAA domain ABC_tran PF00005.22 AIN98394.1 - 0.0001 22.5 0.2 0.35 11.1 0.0 4.5 4 0 0 4 4 3 1 ABC transporter Sigma54_activat PF00158.21 AIN98394.1 - 0.00022 20.7 0.0 0.23 10.8 0.0 3.4 3 0 0 3 3 3 1 Sigma-54 interaction domain RNA_helicase PF00910.17 AIN98394.1 - 0.00034 20.7 0.2 4.3 7.5 0.0 4.6 4 0 0 4 4 4 1 RNA helicase DUF258 PF03193.11 AIN98394.1 - 0.00056 19.1 0.1 7.7 5.6 0.0 3.7 3 0 0 3 3 3 0 Protein of unknown function, DUF258 AAA_29 PF13555.1 AIN98394.1 - 0.00065 19.1 3.2 1.3 8.6 0.0 4.7 5 0 0 5 5 4 1 P-loop containing region of AAA domain Mg_chelatase PF01078.16 AIN98394.1 - 0.0061 15.7 7.8 0.19 10.8 0.0 4.0 4 0 0 4 4 3 2 Magnesium chelatase, subunit ChlI AAA_10 PF12846.2 AIN98394.1 - 0.021 14.2 3.5 18 4.6 0.0 4.6 4 0 0 4 4 4 0 AAA-like domain ResIII PF04851.10 AIN98394.1 - 0.027 14.3 0.3 4.8 6.9 0.1 3.7 3 0 0 3 3 3 0 Type III restriction enzyme, res subunit MobB PF03205.9 AIN98394.1 - 0.041 13.6 1.8 3.4 7.3 0.0 4.0 4 0 0 4 4 4 0 Molybdopterin guanine dinucleotide synthesis protein B PhoH PF02562.11 AIN98394.1 - 0.086 12.0 5.7 0.12 11.5 0.0 3.3 4 0 0 4 4 4 0 PhoH-like protein Arch_ATPase PF01637.13 AIN98394.1 - 0.1 12.2 0.0 11 5.6 0.0 3.7 4 0 0 4 4 4 0 Archaeal ATPase NTPase_1 PF03266.10 AIN98394.1 - 0.11 12.1 1.6 86 2.7 0.0 4.4 4 0 0 4 4 4 0 NTPase SRP54 PF00448.17 AIN98394.1 - 0.15 11.4 3.4 3.2 7.1 0.1 3.7 4 0 0 4 4 4 0 SRP54-type protein, GTPase domain AAA_24 PF13479.1 AIN98394.1 - 1.2 8.6 6.9 18 4.8 0.1 4.5 5 0 0 5 5 4 0 AAA domain Lactamase_B_2 PF12706.2 AIN98395.1 - 1.4e-11 44.3 0.1 2e-11 43.8 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 AIN98395.1 - 1.2e-07 31.5 0.1 3.3e-07 30.1 0.1 1.7 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 AIN98396.1 - 0.0022 17.5 0.0 0.0026 17.3 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Adap_comp_sub PF00928.16 AIN98397.1 - 1.5e-81 273.3 0.2 1.9e-81 273.0 0.1 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 AIN98397.1 - 0.0046 16.6 0.3 0.008 15.8 0.2 1.4 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Pkinase PF00069.20 AIN98398.1 - 1.7e-14 53.5 0.0 2.1e-06 27.0 0.0 2.4 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 AIN98398.1 - 0.00059 18.9 0.0 0.2 10.6 0.0 2.4 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.20 AIN98400.1 - 3.9e-24 85.2 0.0 3.8e-19 68.8 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 AIN98400.1 - 3.6e-08 32.7 0.0 4.4e-07 29.2 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 AIN98400.1 - 0.00055 18.9 0.0 0.0011 18.0 0.0 1.5 1 0 0 1 1 1 1 Kinase-like ChaC PF04752.7 AIN98401.1 - 5.4e-43 146.9 0.0 7.4e-42 143.3 0.0 2.0 1 1 0 1 1 1 1 ChaC-like protein WD40 PF00400.27 AIN98402.1 - 9.3e-12 44.3 1.1 2.6e-06 27.1 0.0 3.9 3 0 0 3 3 3 3 WD domain, G-beta repeat SHS2_Rpb7-N PF03876.12 AIN98404.1 - 0.086 12.9 0.0 18 5.5 0.0 2.7 2 0 0 2 2 2 0 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 GTP_EFTU PF00009.22 AIN98405.1 - 5e-37 127.1 1.5 3.5e-36 124.3 1.0 2.2 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 AIN98405.1 - 1.2e-07 31.7 0.1 2.2e-07 30.8 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 AIN98405.1 - 1.3e-05 25.7 0.0 3.4e-05 24.3 0.0 1.7 1 0 0 1 1 1 1 Miro-like protein PduV-EutP PF10662.4 AIN98405.1 - 2.4e-05 23.8 0.0 6.4e-05 22.4 0.0 1.7 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation FeoB_N PF02421.13 AIN98405.1 - 0.00011 21.4 0.0 0.00024 20.4 0.0 1.5 1 0 0 1 1 1 1 Ferrous iron transport protein B SRPRB PF09439.5 AIN98405.1 - 0.00018 20.8 0.0 0.00037 19.7 0.0 1.4 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Dynamin_N PF00350.18 AIN98405.1 - 0.00029 20.7 3.5 0.22 11.3 0.0 3.1 2 1 1 3 3 3 2 Dynamin family IF-2 PF11987.3 AIN98405.1 - 0.0021 17.9 0.0 0.0069 16.2 0.0 1.9 1 0 0 1 1 1 1 Translation-initiation factor 2 WD40 PF00400.27 AIN98406.1 - 6.8e-24 82.8 17.0 8.1e-05 22.3 0.1 7.5 8 0 0 8 8 8 6 WD domain, G-beta repeat MORN PF02493.15 AIN98408.1 - 1e-05 24.9 11.7 0.22 11.3 0.0 3.5 3 0 0 3 3 3 3 MORN repeat CPSase_L_D2 PF02786.12 AIN98409.1 - 0.017 14.4 0.1 0.032 13.5 0.1 1.4 1 0 0 1 1 1 0 Carbamoyl-phosphate synthase L chain, ATP binding domain Ribonuc_red_sm PF00268.16 AIN98410.1 - 1.2e-110 369.0 0.2 1.4e-110 368.7 0.2 1.0 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain Atg8 PF02991.11 AIN98411.1 - 1.1e-11 44.5 0.0 6.4e-11 42.1 0.0 1.9 2 0 0 2 2 2 1 Autophagy protein Atg8 ubiquitin like APG12 PF04110.8 AIN98411.1 - 0.00033 20.7 0.0 0.00049 20.2 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 WRKY PF03106.10 AIN98411.1 - 0.11 12.3 0.0 0.2 11.5 0.0 1.4 1 0 0 1 1 1 0 WRKY DNA -binding domain GOLGA2L5 PF15070.1 AIN98413.1 - 1.7 7.0 9.7 0.44 8.9 1.9 2.2 2 0 0 2 2 2 0 Putative golgin subfamily A member 2-like protein 5 Muted PF14942.1 AIN98413.1 - 4.6 7.1 7.8 3.1 7.6 2.6 2.1 2 0 0 2 2 2 0 Organelle biogenesis, Muted-like protein CALCOCO1 PF07888.6 AIN98414.1 - 0.0011 17.4 3.0 0.0011 17.4 2.1 3.2 3 0 0 3 3 3 2 Calcium binding and coiled-coil domain (CALCOCO1) like HAP1_N PF04849.8 AIN98414.1 - 0.0025 16.8 3.3 0.0025 16.8 2.3 3.1 3 0 0 3 3 3 2 HAP1 N-terminal conserved region ATG16 PF08614.6 AIN98414.1 - 3.2 7.5 34.8 0.55 10.0 2.5 5.2 4 1 0 4 4 4 0 Autophagy protein 16 (ATG16) COMP PF11598.3 AIN98415.1 - 0.0036 17.3 1.9 1.1 9.3 0.1 3.7 3 0 0 3 3 3 2 Cartilage oligomeric matrix protein Methyltransf_28 PF02636.12 AIN98417.1 - 1.5e-36 126.0 0.1 2e-36 125.6 0.0 1.1 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_18 PF12847.2 AIN98417.1 - 8.7e-05 23.0 0.0 0.00021 21.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 AIN98417.1 - 0.0001 21.9 0.0 0.00017 21.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain RrnaAD PF00398.15 AIN98417.1 - 0.00043 19.3 0.0 0.00077 18.5 0.0 1.3 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_26 PF13659.1 AIN98417.1 - 0.0066 16.4 0.0 0.016 15.2 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 AIN98417.1 - 0.013 15.9 0.0 0.025 15.0 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain PRMT5 PF05185.11 AIN98417.1 - 0.026 13.4 0.0 0.041 12.8 0.0 1.2 1 0 0 1 1 1 0 PRMT5 arginine-N-methyltransferase Methyltransf_32 PF13679.1 AIN98417.1 - 0.027 14.1 0.0 0.048 13.3 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain zf-DHHC PF01529.15 AIN98418.1 - 1.4e-29 102.6 4.7 1.4e-29 102.6 3.3 1.7 1 1 1 2 2 2 1 DHHC palmitoyltransferase polyprenyl_synt PF00348.12 AIN98419.1 - 1.2e-53 181.5 0.1 1.5e-53 181.2 0.1 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase Ribosomal_L28e PF01778.12 AIN98421.1 - 2.9e-28 98.6 0.6 4.3e-28 98.0 0.0 1.6 2 0 0 2 2 2 1 Ribosomal L28e protein family Mak16 PF04874.9 AIN98421.1 - 5.1e-14 52.1 18.6 5.1e-14 52.1 12.9 2.2 2 0 0 2 2 2 1 Mak16 protein C-terminal region RNase_H2-Ydr279 PF09468.5 AIN98421.1 - 0.022 13.9 2.7 0.026 13.7 1.9 1.2 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) Exonuc_VII_L PF02601.10 AIN98421.1 - 0.38 9.8 5.1 0.49 9.5 3.5 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit MORN PF02493.15 AIN98423.1 - 8.9e-47 154.1 83.5 4.8e-05 22.8 0.1 13.0 13 0 0 13 13 13 12 MORN repeat EF-hand_1 PF00036.27 AIN98424.1 - 2.1e-25 86.0 7.9 2.6e-08 32.5 0.3 4.1 4 0 0 4 4 4 3 EF hand EF-hand_7 PF13499.1 AIN98424.1 - 6.6e-24 83.8 0.8 8.4e-13 48.2 0.2 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 AIN98424.1 - 2.1e-20 70.6 5.2 7.2e-08 31.6 0.1 3.8 3 1 0 3 3 3 3 EF-hand domain EF-hand_5 PF13202.1 AIN98424.1 - 3.2e-19 67.3 7.5 6e-06 25.3 0.1 3.4 3 0 0 3 3 3 3 EF hand EF-hand_8 PF13833.1 AIN98424.1 - 4.9e-19 67.6 7.9 1.7e-11 43.5 0.3 3.9 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_4 PF12763.2 AIN98424.1 - 2.3e-07 30.4 2.5 0.071 12.8 0.0 3.1 1 1 2 3 3 3 3 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.1 AIN98424.1 - 1e-06 28.5 0.0 9.2e-06 25.4 0.0 2.1 2 0 0 2 2 2 1 EF-hand domain EFhand_Ca_insen PF08726.5 AIN98424.1 - 0.017 15.0 0.3 6.6 6.7 0.0 2.8 2 1 0 2 2 2 0 Ca2+ insensitive EF hand SPARC_Ca_bdg PF10591.4 AIN98424.1 - 0.1 12.6 0.0 0.25 11.3 0.0 1.7 2 0 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region DUF3911 PF13050.1 AIN98424.1 - 0.14 12.3 0.0 0.25 11.4 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3911) MIP PF00230.15 AIN98425.1 - 2.5e-21 76.1 19.9 4e-20 72.2 13.1 2.6 1 1 1 2 2 2 2 Major intrinsic protein FKBP_C PF00254.23 AIN98426.1 - 2.1e-28 98.1 0.0 2.4e-28 97.9 0.0 1.1 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase Pro_isomerase PF00160.16 AIN98428.1 - 6.1e-36 123.9 0.0 7.6e-36 123.6 0.0 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD EF-hand_8 PF13833.1 AIN98429.1 - 1.7e-06 27.5 0.2 3.7e-05 23.2 0.0 2.5 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_7 PF13499.1 AIN98429.1 - 0.00024 21.1 0.1 0.013 15.6 0.1 2.4 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.1 AIN98429.1 - 0.018 14.8 0.0 2 8.5 0.0 3.3 3 1 0 3 3 3 0 EF-hand domain EF-hand_1 PF00036.27 AIN98429.1 - 0.04 13.2 0.0 12 5.4 0.0 3.2 3 1 0 3 3 3 0 EF hand FadA PF09403.5 AIN98429.1 - 0.88 9.5 4.5 1.8 8.5 3.1 1.5 1 0 0 1 1 1 0 Adhesion protein FadA TPR_11 PF13414.1 AIN98430.1 - 0.00052 19.6 0.3 0.051 13.2 0.0 2.7 3 0 0 3 3 3 1 TPR repeat TPR_2 PF07719.12 AIN98430.1 - 0.0041 16.9 0.6 1.5 8.9 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.1 AIN98430.1 - 0.055 13.8 0.4 5.9 7.3 0.1 2.5 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.1 AIN98430.1 - 0.097 12.6 3.9 0.32 10.9 0.1 2.7 3 0 0 3 3 3 0 Tetratricopeptide repeat MAM33 PF02330.11 AIN98431.1 - 1.1e-13 51.4 1.3 1.9e-13 50.6 0.9 1.7 1 1 0 1 1 1 1 Mitochondrial glycoprotein Metallophos PF00149.23 AIN98433.1 - 3.1e-08 33.2 0.0 8.7e-07 28.5 0.0 2.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 AIN98433.1 - 0.00066 19.5 0.4 0.0072 16.1 0.3 2.1 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain HA2 PF04408.18 AIN98434.1 - 1.1e-17 63.8 0.0 2.6e-17 62.7 0.0 1.7 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.26 AIN98434.1 - 4.8e-12 45.5 0.0 1.2e-11 44.3 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 AIN98434.1 - 3.9e-08 32.9 0.0 1.5e-07 31.0 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_22 PF13401.1 AIN98434.1 - 2.4e-05 24.4 0.0 7.7e-05 22.8 0.0 1.9 1 0 0 1 1 1 1 AAA domain R3H PF01424.17 AIN98434.1 - 0.00023 20.8 0.0 0.00082 19.0 0.0 2.1 1 0 0 1 1 1 1 R3H domain T2SE PF00437.15 AIN98434.1 - 0.0069 15.3 0.0 0.012 14.5 0.0 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein Miro PF08477.8 AIN98434.1 - 0.061 13.8 0.0 0.16 12.4 0.0 1.7 1 0 0 1 1 1 0 Miro-like protein TypeIII_RM_meth PF12564.3 AIN98434.1 - 0.25 11.3 0.3 0.57 10.2 0.2 1.6 1 0 0 1 1 1 0 Type III restriction/modification enzyme methylation subunit Ribosomal_L14e PF01929.12 AIN98435.1 - 1.1e-24 86.5 1.6 1.1e-24 86.5 1.1 2.1 2 1 0 2 2 2 1 Ribosomal protein L14 KOW PF00467.24 AIN98435.1 - 2.7e-05 23.7 1.9 3.1e-05 23.4 0.6 1.7 2 0 0 2 2 2 1 KOW motif CoaE PF01121.15 AIN98436.1 - 1.4e-42 145.1 0.0 2.7e-42 144.2 0.0 1.4 1 1 0 1 1 1 1 Dephospho-CoA kinase AAA_18 PF13238.1 AIN98436.1 - 1.8e-05 25.0 0.5 0.049 13.9 0.0 2.7 2 1 1 3 3 3 2 AAA domain AAA_17 PF13207.1 AIN98436.1 - 0.00042 21.1 0.2 0.00086 20.1 0.1 1.9 1 1 0 1 1 1 1 AAA domain Cytidylate_kin2 PF13189.1 AIN98436.1 - 0.00056 19.8 0.5 0.62 9.9 0.1 2.3 2 0 0 2 2 2 2 Cytidylate kinase-like family AAA_33 PF13671.1 AIN98436.1 - 0.014 15.2 0.1 0.21 11.4 0.0 2.5 1 1 0 1 1 1 0 AAA domain UBA PF00627.26 AIN98436.1 - 0.021 14.6 0.1 0.66 9.8 0.0 2.4 2 0 0 2 2 2 0 UBA/TS-N domain DUF1832 PF08870.6 AIN98436.1 - 0.041 13.5 0.1 0.07 12.8 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1832) PRK PF00485.13 AIN98436.1 - 0.046 13.2 0.1 0.11 12.0 0.0 1.6 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family SKI PF01202.17 AIN98436.1 - 0.07 12.9 0.0 1 9.1 0.0 2.1 2 0 0 2 2 2 0 Shikimate kinase tRNA-synt_2c PF01411.14 AIN98437.1 - 1.5e-191 637.5 0.0 1.9e-191 637.1 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (A) tRNA_SAD PF07973.9 AIN98437.1 - 7.5e-11 41.7 0.0 1.9e-10 40.4 0.0 1.8 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain DHHA1 PF02272.14 AIN98437.1 - 0.00052 19.6 0.9 0.0016 18.1 0.6 1.8 1 0 0 1 1 1 1 DHHA1 domain SpoA PF01052.15 AIN98438.1 - 0.012 15.2 0.0 0.027 14.0 0.0 1.5 1 0 0 1 1 1 0 Surface presentation of antigens (SPOA) PTEN_C2 PF10409.4 AIN98438.1 - 0.031 14.0 0.0 0.07 12.8 0.0 1.6 1 0 0 1 1 1 0 C2 domain of PTEN tumour-suppressor protein Ribosomal_L14e PF01929.12 AIN98439.1 - 1.1e-24 86.5 1.6 1.1e-24 86.5 1.1 2.1 2 1 0 2 2 2 1 Ribosomal protein L14 KOW PF00467.24 AIN98439.1 - 2.7e-05 23.7 1.9 3.1e-05 23.4 0.6 1.7 2 0 0 2 2 2 1 KOW motif DUF1358 PF07096.6 AIN98441.1 - 0.061 13.0 0.0 0.14 11.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1358) RNase_PH PF01138.16 AIN98442.1 - 1.3e-08 35.2 0.0 2.8e-08 34.1 0.0 1.6 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.10 AIN98442.1 - 0.00063 19.6 0.2 0.0015 18.3 0.1 1.6 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 Metallophos PF00149.23 AIN98444.1 - 8.6e-09 35.0 0.3 3.7e-08 32.9 0.1 1.9 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 AIN98444.1 - 3e-07 30.4 0.0 5.4e-07 29.5 0.0 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Motile_Sperm PF00635.21 AIN98446.1 - 1.6e-10 40.6 0.0 5.6 6.6 0.0 8.6 10 0 0 10 10 10 5 MSP (Major sperm protein) domain PapD-like PF14874.1 AIN98446.1 - 8.9e-06 25.5 11.7 0.00033 20.5 0.1 7.3 7 2 1 8 8 8 1 Flagellar-associated PapD-like CAF1 PF04857.15 AIN98447.1 - 7.4e-62 209.0 0.2 1.2e-61 208.3 0.1 1.3 1 0 0 1 1 1 1 CAF1 family ribonuclease cobW PF02492.14 AIN98449.1 - 1.5e-25 89.6 0.0 2.2e-25 89.1 0.0 1.2 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.9 AIN98449.1 - 0.013 15.1 0.0 0.043 13.5 0.0 1.8 1 1 0 1 1 1 0 Cobalamin synthesis protein cobW C-terminal domain MobB PF03205.9 AIN98449.1 - 0.019 14.6 0.0 0.035 13.8 0.0 1.4 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_16 PF13191.1 AIN98449.1 - 0.037 13.9 0.0 0.1 12.5 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain AAA_33 PF13671.1 AIN98449.1 - 0.076 12.8 0.0 0.15 11.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 AIN98449.1 - 0.1 12.9 0.0 0.19 12.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.22 AIN98449.1 - 0.1 12.8 0.0 0.18 12.1 0.0 1.3 1 0 0 1 1 1 0 ABC transporter AAA_22 PF13401.1 AIN98449.1 - 0.11 12.6 0.0 0.29 11.2 0.0 1.7 1 1 0 1 1 1 0 AAA domain LAMTOR PF15454.1 AIN98449.1 - 0.18 12.0 0.0 0.31 11.3 0.0 1.3 1 0 0 1 1 1 0 Late endosomal/lysosomal adaptor and MAPK and MTOR activator T2SE PF00437.15 AIN98449.1 - 0.19 10.5 0.0 0.32 9.8 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein RIIa PF02197.12 AIN98450.1 - 0.0022 17.3 0.1 0.0075 15.6 0.1 1.9 1 0 0 1 1 1 1 Regulatory subunit of type II PKA R-subunit DZR PF12773.2 AIN98451.1 - 0.015 15.0 4.0 0.015 15.0 2.8 8.1 3 2 4 7 7 7 0 Double zinc ribbon PI-PLC-X PF00388.14 AIN98452.1 - 2.4e-58 195.6 0.0 4.9e-58 194.6 0.0 1.6 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.14 AIN98452.1 - 5.3e-34 116.7 0.0 1.4e-33 115.4 0.0 1.8 2 0 0 2 2 2 1 Phosphatidylinositol-specific phospholipase C, Y domain C2 PF00168.25 AIN98452.1 - 5.6e-08 32.5 0.0 1.1e-07 31.5 0.0 1.5 1 0 0 1 1 1 1 C2 domain EF-hand_7 PF13499.1 AIN98452.1 - 6.1e-05 23.0 0.4 0.0012 18.9 0.1 2.7 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.27 AIN98452.1 - 0.00015 20.8 0.0 0.0017 17.5 0.0 2.8 3 0 0 3 3 3 1 EF hand EF-hand_6 PF13405.1 AIN98452.1 - 0.00092 18.9 0.1 0.19 11.7 0.0 3.6 2 1 0 2 2 2 1 EF-hand domain Toprim_2 PF13155.1 AIN98452.1 - 0.001 19.3 0.1 0.039 14.2 0.0 2.5 2 0 0 2 2 2 1 Toprim-like EF-hand_like PF09279.6 AIN98452.1 - 0.0019 18.1 0.1 0.0065 16.4 0.0 2.0 2 0 0 2 2 2 1 Phosphoinositide-specific phospholipase C, efhand-like Inhibitor_I67 PF11405.3 AIN98453.1 - 4.5 7.3 7.2 2.7 8.1 0.8 2.7 3 0 0 3 3 3 0 Bromelain inhibitor VI DUF445 PF04286.7 AIN98454.1 - 0.002 17.7 1.5 0.0027 17.2 0.1 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF445) UTP15_C PF09384.5 AIN98456.1 - 2e-38 131.3 0.4 3.2e-38 130.7 0.3 1.3 1 0 0 1 1 1 1 UTP15 C terminal WD40 PF00400.27 AIN98456.1 - 2.3e-20 71.6 0.9 9.1e-05 22.1 0.0 5.6 5 0 0 5 5 5 5 WD domain, G-beta repeat DUF1325 PF07039.6 AIN98456.1 - 0.094 12.3 0.5 0.41 10.2 0.3 1.9 2 0 0 2 2 2 0 SGF29 tudor-like domain AhpC-TSA PF00578.16 AIN98457.1 - 2e-39 134.0 0.0 2.8e-39 133.6 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 AIN98457.1 - 7.1e-16 58.0 0.0 9e-16 57.7 0.0 1.1 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.4 AIN98457.1 - 3.6e-08 32.9 0.1 7.3e-08 31.9 0.1 1.5 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin EIAV_GP90 PF00971.13 AIN98457.1 - 0.075 11.4 0.0 0.094 11.1 0.0 1.1 1 0 0 1 1 1 0 EIAV coat protein, gp90 Pro_isomerase PF00160.16 AIN98458.1 - 6.6e-46 156.3 0.1 9.8e-46 155.7 0.1 1.3 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD DUF4603 PF15376.1 AIN98459.1 - 0.25 8.4 1.5 1.9 5.5 0.2 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4603) Arginase PF00491.16 AIN98460.1 - 6.7e-36 123.9 0.0 7.7e-36 123.8 0.0 1.1 1 0 0 1 1 1 1 Arginase family Tropomyosin_1 PF12718.2 AIN98461.1 - 0.0012 18.7 2.7 0.0012 18.7 1.8 3.5 1 1 1 3 3 3 1 Tropomyosin like DUF1664 PF07889.7 AIN98461.1 - 0.0023 17.7 4.9 0.0023 17.7 3.4 3.9 2 1 2 4 4 4 1 Protein of unknown function (DUF1664) VWA_N PF08399.6 AIN98461.1 - 0.06 13.9 1.6 0.17 12.4 1.1 1.8 1 0 0 1 1 1 0 VWA N-terminal V_ATPase_I PF01496.14 AIN98461.1 - 0.52 8.0 30.9 0.02 12.7 11.2 2.9 1 1 2 3 3 3 0 V-type ATPase 116kDa subunit family Seryl_tRNA_N PF02403.17 AIN98461.1 - 0.84 9.6 38.4 1.3 9.0 0.2 4.4 1 1 1 4 4 4 0 Seryl-tRNA synthetase N-terminal domain Gal4_dimer PF03902.8 AIN98461.1 - 1.2 9.0 8.2 3.2 7.7 0.3 3.7 3 0 0 3 3 3 0 Gal4-like dimerisation domain AAA_13 PF13166.1 AIN98461.1 - 1.8 6.8 29.9 0.033 12.6 14.2 2.2 2 1 0 2 2 2 0 AAA domain Peptidase_M55 PF04951.8 AIN98461.1 - 5.3 6.1 7.4 1.4 8.0 2.6 1.8 1 1 1 2 2 2 0 D-aminopeptidase DUF1767 PF08585.7 AIN98462.1 - 9.2e-16 57.8 0.1 1.7e-15 57.0 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1767) Methyltransf_16 PF10294.4 AIN98463.1 - 3.7e-18 65.5 0.0 5.2e-18 65.0 0.0 1.1 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_31 PF13847.1 AIN98463.1 - 5.3e-10 39.0 0.0 7.8e-10 38.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 AIN98463.1 - 4.2e-08 33.5 0.0 2.9e-07 30.8 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.9 AIN98463.1 - 2.6e-07 30.1 0.0 3.6e-07 29.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_18 PF12847.2 AIN98463.1 - 1.1e-06 29.2 0.1 2.2e-06 28.2 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 AIN98463.1 - 1.9e-05 24.6 0.0 3.2e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain tRNA_U5-meth_tr PF05958.6 AIN98463.1 - 8.8e-05 21.3 0.0 0.00012 20.8 0.0 1.1 1 0 0 1 1 1 1 tRNA (Uracil-5-)-methyltransferase Methyltransf_11 PF08241.7 AIN98463.1 - 0.00015 22.1 0.0 0.0003 21.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 AIN98463.1 - 0.00048 19.3 0.0 0.00065 18.9 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_25 PF13649.1 AIN98463.1 - 0.00076 19.7 0.0 0.0013 19.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain NodS PF05401.6 AIN98463.1 - 0.00092 18.6 0.0 0.0014 18.0 0.0 1.2 1 0 0 1 1 1 1 Nodulation protein S (NodS) Methyltransf_23 PF13489.1 AIN98463.1 - 0.0015 18.3 0.0 0.0022 17.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain RrnaAD PF00398.15 AIN98463.1 - 0.015 14.3 0.0 0.021 13.8 0.0 1.1 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Methyltransf_9 PF08003.6 AIN98463.1 - 0.016 13.9 0.0 0.025 13.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) NTP_transferase PF00483.18 AIN98464.1 - 4.4e-44 150.6 0.0 5.8e-44 150.2 0.0 1.1 1 0 0 1 1 1 1 Nucleotidyl transferase Hexapep PF00132.19 AIN98464.1 - 2.1e-12 45.9 14.0 2.8e-07 29.7 2.4 3.5 1 1 3 4 4 4 4 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.2 AIN98464.1 - 1.1e-11 45.1 0.0 1.5e-11 44.6 0.0 1.2 1 0 0 1 1 1 1 MobA-like NTP transferase domain CTP_transf_3 PF02348.14 AIN98464.1 - 0.024 14.2 0.0 0.039 13.5 0.0 1.3 1 0 0 1 1 1 0 Cytidylyltransferase Hexapep_2 PF14602.1 AIN98464.1 - 0.75 9.4 21.5 0.91 9.1 0.3 3.8 3 1 1 4 4 4 0 Hexapeptide repeat of succinyl-transferase Beach PF02138.13 AIN98465.1 - 5.5e-90 301.4 0.0 8.6e-90 300.8 0.0 1.3 1 0 0 1 1 1 1 Beige/BEACH domain Laminin_G_3 PF13385.1 AIN98465.1 - 9.7e-06 25.9 0.0 3.8e-05 23.9 0.0 2.0 2 0 0 2 2 2 1 Concanavalin A-like lectin/glucanases superfamily PH_BEACH PF14844.1 AIN98465.1 - 0.0096 15.7 0.0 0.024 14.4 0.0 1.6 1 0 0 1 1 1 1 PH domain associated with Beige/BEACH Pro_isomerase PF00160.16 AIN98466.1 - 3.1e-12 46.9 0.0 4e-12 46.5 0.0 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD ATP-synt_C PF00137.16 AIN98467.1 - 1.1e-25 89.2 30.6 5.2e-16 58.3 7.1 2.3 2 0 0 2 2 2 2 ATP synthase subunit C GerA PF03323.8 AIN98467.1 - 1.7 6.6 7.0 4.6 5.2 0.3 2.1 2 0 0 2 2 2 0 Bacillus/Clostridium GerA spore germination protein DUF4064 PF13273.1 AIN98467.1 - 7.8 6.6 13.1 0.76 9.9 2.5 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF4064) Abhydrolase_6 PF12697.2 AIN98468.1 - 1.5e-26 93.7 1.2 2.5e-26 92.9 0.8 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 AIN98468.1 - 8.8e-14 51.4 0.2 1e-12 47.9 0.0 2.1 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 AIN98468.1 - 5.2e-10 39.2 0.1 7.5e-10 38.7 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.3 AIN98468.1 - 8e-06 25.6 0.1 3.4e-05 23.5 0.0 2.1 2 0 0 2 2 2 1 Putative lysophospholipase Ser_hydrolase PF06821.8 AIN98468.1 - 0.0014 18.2 0.0 0.0035 16.9 0.0 1.6 1 0 0 1 1 1 1 Serine hydrolase DUF2305 PF10230.4 AIN98468.1 - 0.0077 15.6 0.0 0.014 14.8 0.0 1.4 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2305) Glyco_trans_4_4 PF13579.1 AIN98468.1 - 0.14 12.3 5.7 1.7 8.7 0.0 2.9 2 1 0 2 2 2 0 Glycosyl transferase 4-like domain LRR_6 PF13516.1 AIN98469.1 - 1.2e-10 40.3 11.4 0.16 12.1 0.0 8.5 9 1 0 9 9 9 4 Leucine Rich repeat LRR_8 PF13855.1 AIN98469.1 - 2.4e-05 24.0 3.0 0.048 13.4 0.0 5.2 4 2 0 4 4 4 2 Leucine rich repeat LRR_4 PF12799.2 AIN98469.1 - 2.6e-05 23.7 2.3 1.2 8.8 0.0 5.2 3 2 1 4 4 4 2 Leucine Rich repeats (2 copies) LRR_7 PF13504.1 AIN98469.1 - 0.077 13.2 7.2 1.6e+02 3.2 0.0 6.8 9 1 0 9 9 9 0 Leucine rich repeat cNMP_binding PF00027.24 AIN98470.1 - 1.1e-07 31.6 0.1 0.012 15.3 0.1 2.5 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain Cupin_2 PF07883.6 AIN98470.1 - 0.09 12.2 0.1 6.1 6.4 0.1 2.5 2 0 0 2 2 2 0 Cupin domain DUF844 PF05815.6 AIN98470.1 - 0.11 11.3 0.2 7.2 5.3 0.0 2.1 2 0 0 2 2 2 0 Baculovirus protein of unknown function (DUF844) DUF2205 PF10224.4 AIN98471.1 - 0.059 12.9 0.4 0.059 12.9 0.3 1.6 2 0 0 2 2 2 0 Predicted coiled-coil protein (DUF2205) DUF1664 PF07889.7 AIN98471.1 - 0.067 12.9 0.4 0.11 12.3 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) DUF2968 PF11180.3 AIN98471.1 - 0.2 11.0 9.6 0.35 10.2 6.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) Herpes_BLRF2 PF05812.7 AIN98473.1 - 0.0026 17.5 0.9 0.0034 17.1 0.6 1.2 1 0 0 1 1 1 1 Herpesvirus BLRF2 protein YjgF_endoribonc PF14588.1 AIN98474.1 - 3.5e-31 108.1 0.2 3.8e-31 108.0 0.1 1.0 1 0 0 1 1 1 1 YjgF/chorismate_mutase-like, putative endoribonuclease Ribonuc_L-PSP PF01042.16 AIN98474.1 - 3.5e-20 71.9 0.1 4.6e-20 71.5 0.1 1.1 1 0 0 1 1 1 1 Endoribonuclease L-PSP Herpes_U34 PF04541.8 AIN98474.1 - 0.1 11.5 0.1 0.15 10.9 0.0 1.3 1 0 0 1 1 1 0 Herpesvirus virion protein U34 ABC_membrane PF00664.18 AIN98475.1 - 5.9e-51 173.4 33.2 4.5e-31 108.2 8.7 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 AIN98475.1 - 1.2e-21 77.4 0.0 2.2e-21 76.6 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_25 PF13481.1 AIN98475.1 - 3.7e-06 26.4 0.3 8.2e-06 25.3 0.0 1.6 2 0 0 2 2 1 1 AAA domain AAA_29 PF13555.1 AIN98475.1 - 9e-05 21.9 0.1 0.00023 20.5 0.1 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.1 AIN98475.1 - 0.00014 21.8 0.0 0.00054 20.0 0.0 2.0 2 0 0 2 2 1 1 AAA ATPase domain AAA_21 PF13304.1 AIN98475.1 - 0.00031 20.8 0.0 0.031 14.2 0.1 2.2 1 1 0 2 2 2 1 AAA domain T2SE PF00437.15 AIN98475.1 - 0.00044 19.2 0.1 0.0012 17.8 0.0 1.6 2 0 0 2 2 2 1 Type II/IV secretion system protein SMC_N PF02463.14 AIN98475.1 - 0.00047 19.4 0.1 0.12 11.6 0.0 2.3 1 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 AIN98475.1 - 0.0013 19.0 0.0 0.0022 18.3 0.0 1.2 1 0 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.13 AIN98475.1 - 0.003 17.1 0.0 0.0055 16.2 0.0 1.4 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase DUF258 PF03193.11 AIN98475.1 - 0.0037 16.4 0.0 0.0072 15.5 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 FtsK_SpoIIIE PF01580.13 AIN98475.1 - 0.005 16.3 0.0 0.01 15.3 0.0 1.4 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA_22 PF13401.1 AIN98475.1 - 0.0054 16.8 0.0 0.015 15.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain CAP_GLY PF01302.20 AIN98475.1 - 0.017 14.8 0.0 0.038 13.7 0.0 1.5 1 0 0 1 1 1 0 CAP-Gly domain AAA_10 PF12846.2 AIN98475.1 - 0.024 14.0 0.0 0.046 13.1 0.0 1.4 1 0 0 1 1 1 0 AAA-like domain Miro PF08477.8 AIN98475.1 - 0.028 14.9 0.0 0.11 12.9 0.0 2.0 2 0 0 2 2 1 0 Miro-like protein ABC_ATPase PF09818.4 AIN98475.1 - 0.036 12.6 0.0 0.063 11.8 0.0 1.3 1 0 0 1 1 1 0 Predicted ATPase of the ABC class AAA_28 PF13521.1 AIN98475.1 - 0.038 13.9 0.0 0.076 12.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 AIN98475.1 - 0.045 13.4 0.1 0.1 12.2 0.0 1.6 1 0 0 1 1 1 0 NACHT domain AAA_14 PF13173.1 AIN98475.1 - 0.045 13.6 0.0 0.09 12.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain Arch_ATPase PF01637.13 AIN98475.1 - 0.11 12.2 0.0 0.19 11.3 0.0 1.3 1 0 0 1 1 1 0 Archaeal ATPase DUF87 PF01935.12 AIN98475.1 - 0.12 12.1 0.4 0.22 11.3 0.3 1.3 1 0 0 1 1 1 0 Domain of unknown function DUF87 cobW PF02492.14 AIN98475.1 - 0.13 11.6 0.2 0.26 10.7 0.1 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain Guanylate_kin PF00625.16 AIN98475.1 - 0.17 11.3 0.0 0.32 10.4 0.0 1.4 1 0 0 1 1 1 0 Guanylate kinase MMR_HSR1 PF01926.18 AIN98475.1 - 0.18 11.7 0.0 0.39 10.6 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_17 PF13207.1 AIN98475.1 - 0.32 11.8 0.0 0.79 10.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 AIN98475.1 - 0.33 11.2 0.0 0.67 10.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain Yip1 PF04893.12 AIN98479.1 - 5e-17 61.9 17.4 5.1e-17 61.8 11.6 1.3 1 1 0 1 1 1 1 Yip1 domain DUF2964 PF11177.3 AIN98479.1 - 0.036 13.9 0.6 0.087 12.7 0.4 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2964) ResB PF05140.9 AIN98479.1 - 0.26 9.8 2.4 0.37 9.2 1.7 1.2 1 0 0 1 1 1 0 ResB-like family ABC_membrane PF00664.18 AIN98480.1 - 1.4e-70 237.8 20.0 8.1e-38 130.4 1.0 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 AIN98480.1 - 3.3e-48 163.4 0.0 1.4e-24 86.9 0.0 2.5 2 0 0 2 2 2 2 ABC transporter AAA_29 PF13555.1 AIN98480.1 - 1.8e-09 36.9 1.0 0.00018 20.9 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain CAP_GLY PF01302.20 AIN98480.1 - 2.8e-09 36.5 0.0 8.5e-09 35.0 0.0 1.8 1 0 0 1 1 1 1 CAP-Gly domain AAA_25 PF13481.1 AIN98480.1 - 4.9e-08 32.6 0.1 0.00014 21.3 0.0 2.9 3 0 0 3 3 2 2 AAA domain SMC_N PF02463.14 AIN98480.1 - 6.8e-08 32.0 1.7 0.069 12.3 0.0 4.0 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 AIN98480.1 - 1.2e-07 32.0 0.0 0.92 9.4 0.3 4.2 3 1 0 4 4 4 1 AAA domain FtsK_SpoIIIE PF01580.13 AIN98480.1 - 1.5e-06 27.8 0.4 0.061 12.7 0.0 2.5 2 0 0 2 2 2 2 FtsK/SpoIIIE family T2SE PF00437.15 AIN98480.1 - 1.2e-05 24.4 0.0 0.026 13.4 0.0 2.4 2 0 0 2 2 2 2 Type II/IV secretion system protein Miro PF08477.8 AIN98480.1 - 1.9e-05 25.1 0.2 0.26 11.7 0.0 2.6 2 0 0 2 2 2 2 Miro-like protein AAA_10 PF12846.2 AIN98480.1 - 2e-05 24.1 0.1 0.11 11.9 0.0 2.4 2 0 0 2 2 2 2 AAA-like domain AAA_17 PF13207.1 AIN98480.1 - 2.2e-05 25.2 0.1 0.089 13.6 0.0 2.8 2 0 0 2 2 2 2 AAA domain DUF258 PF03193.11 AIN98480.1 - 4.5e-05 22.6 0.4 0.004 16.3 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_22 PF13401.1 AIN98480.1 - 7.8e-05 22.8 0.1 0.13 12.4 0.0 3.3 2 1 0 2 2 2 1 AAA domain AAA_23 PF13476.1 AIN98480.1 - 0.00017 22.0 0.1 0.058 13.7 0.0 2.2 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.18 AIN98480.1 - 0.00018 21.4 0.2 0.93 9.4 0.0 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_16 PF13191.1 AIN98480.1 - 0.00019 21.4 1.6 0.078 12.9 0.0 3.3 3 0 0 3 3 3 1 AAA ATPase domain DUF87 PF01935.12 AIN98480.1 - 0.00041 20.2 2.2 0.65 9.7 0.0 2.4 2 0 0 2 2 2 2 Domain of unknown function DUF87 MobB PF03205.9 AIN98480.1 - 0.0013 18.4 1.4 1.3 8.7 0.0 2.6 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B AAA_33 PF13671.1 AIN98480.1 - 0.0013 18.6 0.0 0.3 10.9 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.1 AIN98480.1 - 0.0014 18.5 0.0 0.14 12.0 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 AIN98480.1 - 0.0014 18.9 0.2 0.62 10.3 0.0 2.6 2 0 0 2 2 2 1 AAA domain NACHT PF05729.7 AIN98480.1 - 0.0016 18.0 0.8 0.56 9.8 0.0 2.5 2 0 0 2 2 2 1 NACHT domain TrwB_AAD_bind PF10412.4 AIN98480.1 - 0.002 16.8 0.4 0.36 9.3 0.0 2.3 2 0 0 2 2 2 1 Type IV secretion-system coupling protein DNA-binding domain AAA_30 PF13604.1 AIN98480.1 - 0.0031 17.1 0.7 0.6 9.6 0.1 2.7 2 0 0 2 2 2 1 AAA domain Viral_helicase1 PF01443.13 AIN98480.1 - 0.0035 16.8 0.0 1.1 8.6 0.0 2.5 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase RNA_helicase PF00910.17 AIN98480.1 - 0.011 15.8 0.1 0.94 9.6 0.0 2.6 2 0 0 2 2 2 0 RNA helicase Dynamin_N PF00350.18 AIN98480.1 - 0.014 15.2 0.6 1.1 9.0 0.0 2.3 2 0 0 2 2 2 0 Dynamin family cobW PF02492.14 AIN98480.1 - 0.015 14.7 1.1 3 7.2 0.0 2.7 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain ATP_bind_1 PF03029.12 AIN98480.1 - 0.031 13.8 2.5 2 7.8 0.1 2.5 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein Adeno_IVa2 PF02456.10 AIN98480.1 - 0.13 10.8 0.0 0.75 8.3 0.0 2.0 2 0 0 2 2 2 0 Adenovirus IVa2 protein Septin PF00735.13 AIN98480.1 - 0.2 10.6 0.3 3.6 6.5 0.0 2.1 2 0 0 2 2 2 0 Septin Arch_ATPase PF01637.13 AIN98480.1 - 0.28 10.8 0.6 27 4.3 0.0 3.0 4 0 0 4 4 3 0 Archaeal ATPase DAP3 PF10236.4 AIN98480.1 - 0.98 8.2 3.4 7.7 5.3 0.0 2.9 3 0 0 3 3 3 0 Mitochondrial ribosomal death-associated protein 3 AAA_15 PF13175.1 AIN98480.1 - 1.9 7.4 0.0 16 4.3 0.0 2.0 2 0 0 2 2 2 0 AAA ATPase domain ABC_ATPase PF09818.4 AIN98480.1 - 2.7 6.4 4.0 0.59 8.6 0.1 1.8 2 0 0 2 2 1 0 Predicted ATPase of the ABC class PduV-EutP PF10662.4 AIN98480.1 - 3.8 6.9 5.4 6.8 6.1 0.1 3.2 4 0 0 4 4 3 0 Ethanolamine utilisation - propanediol utilisation adh_short_C2 PF13561.1 AIN98481.1 - 6.7e-20 71.8 0.0 2.3e-19 70.1 0.0 1.8 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 AIN98481.1 - 7e-10 39.0 3.6 1.7e-07 31.3 2.5 3.0 1 1 0 1 1 1 1 short chain dehydrogenase zf-C3HC4 PF00097.20 AIN98482.1 - 6.6e-07 28.8 7.8 1.8e-06 27.5 5.4 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 AIN98482.1 - 0.00085 19.1 8.6 0.0019 18.0 6.0 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.1 AIN98482.1 - 0.0015 18.2 8.0 0.0038 16.9 5.5 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 AIN98482.1 - 0.0074 15.9 2.9 0.018 14.7 2.0 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.1 AIN98482.1 - 0.024 14.6 11.1 0.068 13.2 7.7 1.9 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) RNA_POL_M_15KD PF02150.11 AIN98482.1 - 0.071 12.8 2.9 0.16 11.6 2.0 1.5 1 0 0 1 1 1 0 RNA polymerases M/15 Kd subunit zf-RING_6 PF14835.1 AIN98482.1 - 0.14 11.9 4.8 0.6 9.9 3.3 2.0 1 1 0 1 1 1 0 zf-RING of BARD1-type protein TF_Zn_Ribbon PF08271.7 AIN98482.1 - 0.72 9.2 4.9 1.6 8.0 3.4 1.6 1 0 0 1 1 1 0 TFIIB zinc-binding zf-RING_2 PF13639.1 AIN98482.1 - 3 7.7 13.1 1.4 8.7 7.1 2.0 2 0 0 2 2 2 0 Ring finger domain Hus1 PF04005.7 AIN98483.1 - 2.9e-75 252.9 0.0 3.5e-75 252.6 0.0 1.1 1 0 0 1 1 1 1 Hus1-like protein tRNA-synt_1b PF00579.20 AIN98484.1 - 2.7e-17 62.8 0.0 5.2e-17 61.9 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) AAA_16 PF13191.1 AIN98485.1 - 1.7e-05 24.9 0.0 4.7e-05 23.4 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain AAA_33 PF13671.1 AIN98485.1 - 0.00011 22.1 0.0 0.00073 19.4 0.0 2.4 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.9 AIN98485.1 - 0.0029 17.3 0.0 0.0075 16.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) ABC_tran PF00005.22 AIN98485.1 - 0.0096 16.2 0.0 0.021 15.1 0.0 1.5 1 0 0 1 1 1 1 ABC transporter Mg_chelatase PF01078.16 AIN98485.1 - 0.012 14.7 1.1 0.12 11.4 0.0 2.7 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI tRNA_lig_kinase PF08303.6 AIN98485.1 - 0.018 14.9 0.0 0.12 12.2 0.0 2.0 1 1 0 1 1 1 0 tRNA ligase kinase domain AAA_22 PF13401.1 AIN98485.1 - 0.02 15.0 0.0 0.061 13.4 0.0 1.8 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 AIN98485.1 - 0.031 14.4 0.0 0.065 13.4 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_18 PF13238.1 AIN98485.1 - 0.038 14.3 0.0 0.2 11.9 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.1 AIN98485.1 - 0.065 13.1 0.0 0.13 12.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA PF00004.24 AIN98485.1 - 0.082 13.1 0.0 0.17 12.0 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) NACHT PF05729.7 AIN98485.1 - 0.097 12.3 0.0 0.23 11.1 0.0 1.6 1 0 0 1 1 1 0 NACHT domain MobB PF03205.9 AIN98485.1 - 0.1 12.2 0.0 0.33 10.6 0.0 1.8 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B ATP_bind_1 PF03029.12 AIN98485.1 - 0.12 11.9 0.0 0.2 11.1 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein AAA_17 PF13207.1 AIN98485.1 - 0.14 12.9 0.0 0.31 11.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain Arch_ATPase PF01637.13 AIN98485.1 - 0.51 10.0 0.0 0.91 9.1 0.0 1.3 1 0 0 1 1 1 0 Archaeal ATPase V-ATPase_G PF03179.10 AIN98488.1 - 6.5e-23 81.0 13.3 7.1e-23 80.9 9.2 1.0 1 0 0 1 1 1 1 Vacuolar (H+)-ATPase G subunit K167R PF08065.7 AIN98488.1 - 0.18 11.8 2.8 1.1 9.4 1.9 2.0 1 1 0 1 1 1 0 K167R (NUC007) repeat DUF3154 PF11351.3 AIN98488.1 - 1.1 9.0 7.1 0.57 9.9 1.4 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3154) YlqD PF11068.3 AIN98488.1 - 1.3 9.0 6.8 1.6 8.7 4.7 1.2 1 0 0 1 1 1 0 YlqD protein DUF4407 PF14362.1 AIN98488.1 - 3.7 6.4 8.8 4.2 6.2 6.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF883 PF05957.8 AIN98488.1 - 3.9 7.9 11.1 3.5 8.0 3.6 2.1 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) Ribonuclease_3 PF00636.21 AIN98491.1 - 0.0034 17.8 0.1 0.34 11.3 0.0 2.9 2 1 0 2 2 2 1 Ribonuclease III domain Ribonucleas_3_3 PF14622.1 AIN98491.1 - 0.014 15.3 0.0 2.9 7.8 0.0 3.0 2 0 0 2 2 2 0 Ribonuclease-III-like ADH_N PF08240.7 AIN98492.1 - 1.7e-27 95.3 7.9 1.7e-27 95.3 5.5 2.3 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 AIN98492.1 - 2.3e-23 82.1 0.0 4.4e-23 81.2 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 AIN98492.1 - 3.5e-06 26.2 0.2 5.8e-06 25.5 0.1 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ADH_zinc_N_2 PF13602.1 AIN98492.1 - 1.7e-05 25.6 0.0 3.4e-05 24.7 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.16 AIN98492.1 - 7.4e-05 22.3 0.4 0.00013 21.5 0.2 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_2 PF03446.10 AIN98492.1 - 7.9e-05 22.5 0.3 0.00014 21.7 0.2 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase Shikimate_DH PF01488.15 AIN98492.1 - 0.00019 21.5 0.0 0.00047 20.2 0.0 1.6 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase NAD_binding_10 PF13460.1 AIN98492.1 - 0.00021 21.3 0.0 0.00033 20.7 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding 3HCDH_N PF02737.13 AIN98492.1 - 0.023 14.3 0.2 0.036 13.7 0.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ApbA PF02558.11 AIN98492.1 - 0.061 12.7 0.1 0.061 12.7 0.1 1.6 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA DUF364 PF04016.7 AIN98492.1 - 0.065 12.5 0.0 0.11 11.8 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF364) XdhC_C PF13478.1 AIN98492.1 - 0.096 13.0 0.0 0.16 12.2 0.0 1.3 1 0 0 1 1 1 0 XdhC Rossmann domain ThiF PF00899.16 AIN98492.1 - 4.9 6.9 6.1 4.9 6.9 2.3 2.3 2 1 1 3 3 3 0 ThiF family ABC_tran PF00005.22 AIN98494.1 - 3.6e-30 105.0 0.0 6e-30 104.3 0.0 1.4 1 0 0 1 1 1 1 ABC transporter ABC2_membrane PF01061.19 AIN98494.1 - 4.4e-23 81.5 19.5 4.4e-23 81.5 13.5 2.7 3 0 0 3 3 3 1 ABC-2 type transporter AAA_21 PF13304.1 AIN98494.1 - 3.4e-06 27.2 0.1 0.00018 21.5 0.0 2.3 1 1 0 1 1 1 1 AAA domain ABC2_membrane_3 PF12698.2 AIN98494.1 - 3.6e-05 22.9 17.1 3.6e-05 22.9 11.8 2.4 2 0 0 2 2 2 1 ABC-2 family transporter protein AAA_16 PF13191.1 AIN98494.1 - 5.3e-05 23.2 0.1 0.00013 22.0 0.1 1.6 1 0 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.1 AIN98494.1 - 0.00052 19.4 0.1 0.0022 17.4 0.1 2.0 2 0 0 2 2 2 1 P-loop containing region of AAA domain DUF258 PF03193.11 AIN98494.1 - 0.001 18.3 0.1 0.0023 17.1 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_22 PF13401.1 AIN98494.1 - 0.0053 16.8 0.0 0.025 14.7 0.1 2.2 2 1 0 2 2 1 1 AAA domain AAA_17 PF13207.1 AIN98494.1 - 0.009 16.8 0.2 0.018 15.8 0.1 1.5 1 0 0 1 1 1 1 AAA domain AAA_23 PF13476.1 AIN98494.1 - 0.02 15.2 0.0 0.035 14.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.1 AIN98494.1 - 0.044 13.1 0.2 0.1 12.0 0.1 1.5 1 0 0 1 1 1 0 AAA domain SbcCD_C PF13558.1 AIN98494.1 - 0.1 12.5 0.0 0.73 9.7 0.0 2.4 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_30 PF13604.1 AIN98494.1 - 0.12 11.8 0.2 0.22 11.0 0.1 1.3 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 AIN98494.1 - 0.14 12.4 0.3 0.26 11.5 0.2 1.4 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.1 AIN98494.1 - 0.66 9.9 4.1 0.23 11.3 0.8 1.7 2 0 0 2 2 2 0 AAA domain Cmc1 PF08583.5 AIN98495.1 - 0.077 12.7 1.1 0.17 11.7 0.8 1.5 1 0 0 1 1 1 0 Cytochrome c oxidase biogenesis protein Cmc1 like Hormone_5 PF00184.12 AIN98497.1 - 0.0055 17.2 1.1 0.0055 17.2 0.8 1.5 2 0 0 2 2 2 1 Neurohypophysial hormones, C-terminal Domain Aldose_epim PF01263.15 AIN98498.1 - 5.2e-54 183.3 0.0 1.2e-53 182.2 0.0 1.5 1 1 0 1 1 1 1 Aldose 1-epimerase FtsX PF02687.16 AIN98500.1 - 3.9e-24 84.7 32.4 9.7e-14 51.1 11.6 5.3 5 0 0 5 5 5 3 FtsX-like permease family CHAP PF05257.11 AIN98501.1 - 2.6e-08 33.5 3.2 2.9e-05 23.7 0.0 2.3 2 0 0 2 2 2 2 CHAP domain Lyase_8_C PF02884.12 AIN98502.1 - 0.088 12.8 0.0 0.23 11.5 0.0 1.6 1 0 0 1 1 1 0 Polysaccharide lyase family 8, C-terminal beta-sandwich domain AMPKBI PF04739.10 AIN98504.1 - 8.2e-18 64.1 0.8 1.1e-17 63.7 0.0 1.6 2 0 0 2 2 2 1 5'-AMP-activated protein kinase beta subunit, interation domain PAP2_3 PF14378.1 AIN98505.1 - 0.048 13.1 1.5 1.2 8.5 0.0 2.1 1 1 1 2 2 2 0 PAP2 superfamily Kinesin-relat_1 PF12711.2 AIN98506.1 - 0.077 13.4 1.9 0.091 13.1 1.3 1.1 1 0 0 1 1 1 0 Kinesin motor DUF3523 PF12037.3 AIN98506.1 - 0.11 11.5 1.0 0.12 11.3 0.7 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3523) SET PF00856.23 AIN98507.1 - 4.2e-12 46.6 0.0 2.8e-11 44.0 0.0 2.0 1 1 0 1 1 1 1 SET domain FtsJ PF01728.14 AIN98508.1 - 1.4e-48 165.2 0.0 1.7e-48 165.0 0.0 1.1 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_23 PF13489.1 AIN98508.1 - 0.0014 18.3 0.0 0.0018 17.9 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain AMP-binding PF00501.23 AIN98509.1 - 3.9e-89 298.9 0.0 4.8e-89 298.6 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 AIN98509.1 - 1.8e-14 54.4 1.2 3.7e-14 53.4 0.8 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain EF-hand_8 PF13833.1 AIN98510.1 - 6.1e-06 25.7 1.2 0.14 11.7 0.0 3.3 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_6 PF13405.1 AIN98510.1 - 7.7e-06 25.3 0.4 0.23 11.4 0.0 3.2 3 0 0 3 3 3 2 EF-hand domain EF-hand_7 PF13499.1 AIN98510.1 - 5.6e-05 23.2 0.0 0.01 15.9 0.0 3.0 2 1 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.27 AIN98510.1 - 0.00029 19.9 0.0 0.095 12.0 0.0 2.8 2 0 0 2 2 2 2 EF hand XRN_N PF03159.13 AIN98511.1 - 4.2e-44 150.7 0.0 8.5e-44 149.7 0.0 1.5 1 1 0 1 1 1 1 XRN 5'-3' exonuclease N-terminus Tropomyosin PF00261.15 AIN98512.1 - 0.54 9.2 9.9 3 6.8 2.0 2.2 1 1 1 2 2 2 0 Tropomyosin GFO_IDH_MocA PF01408.17 AIN98513.1 - 4.8e-12 46.4 0.1 1.9e-11 44.5 0.0 2.1 2 0 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold F420_oxidored PF03807.12 AIN98513.1 - 0.00084 19.7 0.2 0.0033 17.8 0.0 2.1 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent CoA_binding_3 PF13727.1 AIN98513.1 - 0.018 14.8 0.0 0.044 13.6 0.0 1.6 1 1 0 1 1 1 0 CoA-binding domain AAA_10 PF12846.2 AIN98514.1 - 0.0076 15.7 0.2 0.011 15.2 0.1 1.1 1 0 0 1 1 1 1 AAA-like domain CAF1 PF04857.15 AIN98516.1 - 4.2e-42 144.3 0.0 5.5e-42 143.9 0.0 1.1 1 0 0 1 1 1 1 CAF1 family ribonuclease Kelch_3 PF13415.1 AIN98517.1 - 2.4e-16 59.3 10.9 1.9e-08 34.2 0.2 6.4 5 0 0 5 5 5 3 Galactose oxidase, central domain Kelch_4 PF13418.1 AIN98517.1 - 3.9e-14 52.1 9.8 0.00086 19.0 0.0 5.8 5 0 0 5 5 5 4 Galactose oxidase, central domain Kelch_5 PF13854.1 AIN98517.1 - 7.2e-11 41.7 13.6 0.001 18.9 0.4 5.7 5 0 0 5 5 5 3 Kelch motif Kelch_1 PF01344.20 AIN98517.1 - 1.1e-09 37.6 1.7 0.014 14.9 0.0 4.9 4 0 0 4 4 4 2 Kelch motif Kelch_6 PF13964.1 AIN98517.1 - 2.5e-08 33.7 10.6 0.25 11.5 0.0 6.2 5 1 1 6 6 6 3 Kelch motif Kelch_2 PF07646.10 AIN98517.1 - 6.1e-05 22.6 7.9 2 8.3 0.1 5.8 5 1 0 5 5 5 2 Kelch motif tRNA_bind PF01588.15 AIN98518.1 - 8.2e-13 48.0 0.5 1.2e-12 47.4 0.3 1.2 1 0 0 1 1 1 1 Putative tRNA binding domain zf-RanBP PF00641.13 AIN98518.1 - 0.00055 18.9 4.4 0.00097 18.1 3.0 1.4 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others DZR PF12773.2 AIN98518.1 - 0.01 15.6 2.3 0.021 14.6 1.6 1.5 1 0 0 1 1 1 0 Double zinc ribbon zf-ribbon_3 PF13248.1 AIN98518.1 - 0.058 12.6 1.4 0.14 11.4 1.0 1.6 1 0 0 1 1 1 0 zinc-ribbon domain Cache_1 PF02743.13 AIN98518.1 - 0.091 12.3 0.3 0.14 11.6 0.2 1.3 1 0 0 1 1 1 0 Cache domain PvlArgDC PF01862.11 AIN98518.1 - 0.1 12.2 0.2 0.26 10.9 0.1 1.6 1 1 1 2 2 2 0 Pyruvoyl-dependent arginine decarboxylase (PvlArgDC) Lactamase_B PF00753.22 AIN98519.1 - 7.5e-12 45.2 0.4 1.8e-08 34.2 0.2 2.2 2 0 0 2 2 2 2 Metallo-beta-lactamase superfamily PAP2 PF01569.16 AIN98520.1 - 1e-10 41.3 1.6 1e-10 41.3 1.1 2.1 1 1 1 2 2 2 1 PAP2 superfamily DUF212 PF02681.9 AIN98520.1 - 0.015 14.9 1.5 1.2 8.8 0.2 2.6 1 1 0 2 2 2 0 Divergent PAP2 family ThiF PF00899.16 AIN98521.1 - 4.3e-49 165.8 0.7 6e-34 116.7 0.0 2.6 2 0 0 2 2 2 2 ThiF family UBACT PF02134.16 AIN98521.1 - 1.3e-28 98.3 0.2 4.8e-21 74.0 0.0 3.0 3 0 0 3 3 3 2 Repeat in ubiquitin-activating (UBA) protein UBA_e1_C PF09358.5 AIN98521.1 - 6.7e-27 94.1 0.0 1.3e-26 93.2 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-activating enzyme e1 C-terminal domain UBA_e1_thiolCys PF10585.4 AIN98521.1 - 1e-21 76.0 0.1 6.8e-21 73.3 0.0 2.2 2 0 0 2 2 2 1 Ubiquitin-activating enzyme active site Shikimate_DH PF01488.15 AIN98521.1 - 0.0019 18.2 1.0 0.57 10.2 0.0 2.5 2 0 0 2 2 2 2 Shikimate / quinate 5-dehydrogenase Kinesin PF00225.18 AIN98522.1 - 7.4e-86 287.8 0.0 1.6e-85 286.7 0.0 1.6 1 0 0 1 1 1 1 Kinesin motor domain HET-s_218-289 PF11558.3 AIN98522.1 - 0.053 13.5 0.0 0.13 12.2 0.0 1.6 1 0 0 1 1 1 0 Het-s 218-289 MYCBPAP PF14646.1 AIN98523.1 - 8.8e-11 41.1 3.7 0.0002 20.1 0.0 3.1 3 0 0 3 3 3 3 MYCBP-associated protein family ATG11 PF10377.4 AIN98524.1 - 0.18 11.7 0.0 0.34 10.8 0.0 1.4 1 0 0 1 1 1 0 Autophagy-related protein 11 TMEM192 PF14802.1 AIN98525.1 - 0.12 11.2 0.4 0.18 10.6 0.3 1.1 1 0 0 1 1 1 0 TMEM192 family HemY_N PF07219.8 AIN98526.1 - 0.041 13.4 0.9 0.041 13.4 0.6 2.0 1 1 0 2 2 2 0 HemY protein N-terminus DUF3784 PF12650.2 AIN98526.1 - 0.16 11.8 0.7 0.57 10.1 0.5 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF3784) Inh PF02974.9 AIN98527.1 - 0.081 12.5 0.0 0.18 11.3 0.0 1.6 1 0 0 1 1 1 0 Protease inhibitor Inh BING4CT PF08149.6 AIN98528.1 - 6.2e-32 108.9 0.1 3.1e-31 106.7 0.0 2.2 2 0 0 2 2 2 1 BING4CT (NUC141) domain WD40 PF00400.27 AIN98528.1 - 6.7e-09 35.2 0.2 1.3e-07 31.2 0.0 2.8 2 0 0 2 2 2 1 WD domain, G-beta repeat Sec10 PF07393.6 AIN98529.1 - 8.9e-28 96.9 6.1 3.9e-25 88.1 0.0 3.1 3 0 0 3 3 3 3 Exocyst complex component Sec10 DUF1510 PF07423.6 AIN98530.1 - 0.0007 19.0 2.8 0.0014 17.9 1.9 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1510) U79_P34 PF03064.11 AIN98530.1 - 0.011 15.2 2.8 0.022 14.2 1.9 1.4 1 0 0 1 1 1 0 HSV U79 / HCMV P34 DUF3357 PF11837.3 AIN98530.1 - 0.02 14.7 0.2 0.097 12.5 0.1 2.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3357) Shisa PF13908.1 AIN98530.1 - 0.055 13.6 0.4 0.96 9.6 0.1 2.5 2 0 0 2 2 2 0 Wnt and FGF inhibitory regulator SpoIIIAH PF12685.2 AIN98530.1 - 0.057 12.9 6.2 0.11 12.0 3.3 2.0 2 0 0 2 2 2 0 SpoIIIAH-like protein Ycf1 PF05758.7 AIN98530.1 - 0.3 8.7 2.2 0.38 8.4 1.5 1.1 1 0 0 1 1 1 0 Ycf1 DUF3302 PF11742.3 AIN98530.1 - 0.84 9.5 0.0 0.84 9.5 0.0 3.2 4 0 0 4 4 4 0 Protein of unknown function (DUF3302) OAD_gamma PF04277.8 AIN98530.1 - 2.1 8.7 9.5 19 5.7 5.9 3.0 2 1 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain DUF2517 PF10725.4 AIN98530.1 - 2.4 7.9 7.2 0.21 11.2 0.6 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF2517) FYDLN_acid PF09538.5 AIN98530.1 - 8.5 7.0 9.8 42 4.7 5.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) DIM1 PF02966.11 AIN98531.1 - 7.9e-30 103.0 0.2 9.5e-26 89.8 0.1 2.2 2 0 0 2 2 2 2 Mitosis protein DIM1 Fibrillarin PF01269.12 AIN98532.1 - 0.14 11.0 0.0 0.25 10.2 0.0 1.2 1 0 0 1 1 1 0 Fibrillarin PriCT_2 PF08707.6 AIN98533.1 - 1.2e-16 60.3 1.7 2.3e-16 59.3 1.2 1.5 1 0 0 1 1 1 1 Primase C terminal 2 (PriCT-2) DNA_primase_S PF01896.14 AIN98533.1 - 0.014 15.1 0.0 0.026 14.3 0.0 1.4 1 0 0 1 1 1 0 Eukaryotic and archaeal DNA primase small subunit Thiolase_C PF02803.13 AIN98534.1 - 1.9e-12 46.6 1.4 2.2e-11 43.2 0.0 2.7 2 1 1 3 3 3 1 Thiolase, C-terminal domain Thiolase_N PF00108.18 AIN98534.1 - 2.7e-09 36.4 3.1 3.8e-08 32.6 0.6 2.6 2 1 0 2 2 2 1 Thiolase, N-terminal domain ketoacyl-synt PF00109.21 AIN98534.1 - 2.5e-07 30.4 5.2 1.9e-06 27.5 3.6 2.4 1 1 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.5 AIN98534.1 - 0.002 17.7 1.3 0.12 12.0 0.8 2.7 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Ketoacyl-synt_C PF02801.17 AIN98534.1 - 8.3 6.2 7.5 8.7 6.2 0.0 3.7 4 1 1 5 5 5 0 Beta-ketoacyl synthase, C-terminal domain COX17 PF05051.8 AIN98535.1 - 7.6e-06 25.8 0.5 1.2e-05 25.2 0.4 1.2 1 0 0 1 1 1 1 Cytochrome C oxidase copper chaperone (COX17) AMP-binding PF00501.23 AIN98536.1 - 1.6e-86 290.3 0.1 2e-86 289.9 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 AIN98536.1 - 5.3e-14 52.9 0.3 1.2e-13 51.8 0.2 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain RRM_1 PF00076.17 AIN98537.1 - 5.7e-12 45.0 0.0 8.9e-12 44.4 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 AIN98537.1 - 2.7e-09 36.8 0.0 4.9e-09 36.0 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 AIN98537.1 - 4.4e-08 32.8 0.0 7.3e-08 32.1 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 AIN98538.1 - 2e-13 49.7 0.0 3.4e-13 49.0 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 AIN98538.1 - 1.4e-06 28.1 0.0 2.4e-06 27.4 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 AIN98538.1 - 0.0009 19.0 0.0 0.0018 18.0 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) MMR_HSR1 PF01926.18 AIN98539.1 - 1.2e-09 38.1 0.0 3.2e-09 36.7 0.0 1.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase Dynamin_N PF00350.18 AIN98539.1 - 2.1e-05 24.4 0.2 0.00012 21.9 0.1 2.1 1 1 1 2 2 2 1 Dynamin family AAA_29 PF13555.1 AIN98539.1 - 5e-05 22.7 0.0 0.0044 16.5 0.0 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain DUF258 PF03193.11 AIN98539.1 - 0.00044 19.4 0.0 0.0009 18.4 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF258 GTP_EFTU PF00009.22 AIN98539.1 - 0.0041 16.5 0.0 3.8 6.9 0.0 3.1 2 1 0 2 2 2 2 Elongation factor Tu GTP binding domain ABC_tran PF00005.22 AIN98539.1 - 0.076 13.3 0.0 0.19 12.0 0.0 1.6 1 0 0 1 1 1 0 ABC transporter FeoB_N PF02421.13 AIN98539.1 - 0.1 11.8 0.0 0.19 10.9 0.0 1.4 1 0 0 1 1 1 0 Ferrous iron transport protein B T2SE PF00437.15 AIN98539.1 - 0.1 11.4 0.1 1.5 7.6 0.0 2.2 2 0 0 2 2 2 0 Type II/IV secretion system protein DUF1738 PF08401.6 AIN98540.1 - 0.0018 17.9 0.0 0.018 14.7 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF1738) DUF1738 PF08401.6 AIN98541.1 - 0.00015 21.5 0.7 0.094 12.4 0.2 3.1 2 1 1 3 3 3 2 Domain of unknown function (DUF1738) DUF676 PF05057.9 AIN98543.1 - 4.5e-12 45.7 0.0 9.4e-10 38.1 0.0 2.7 2 1 0 2 2 2 2 Putative serine esterase (DUF676) FAD-oxidase_C PF02913.14 AIN98546.1 - 1.1e-44 152.7 0.0 1.9e-44 151.8 0.0 1.4 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.18 AIN98546.1 - 5.7e-30 103.6 2.0 9.4e-30 102.8 0.8 1.8 2 0 0 2 2 2 1 FAD binding domain SET PF00856.23 AIN98547.1 - 1.5e-10 41.5 0.0 3.4e-10 40.4 0.0 1.6 1 0 0 1 1 1 1 SET domain zf-MYND PF01753.13 AIN98547.1 - 0.98 9.3 17.5 0.037 13.8 7.0 2.4 2 1 0 2 2 2 0 MYND finger Na_H_Exchanger PF00999.16 AIN98548.1 - 2.3e-45 154.7 44.4 3.2e-45 154.3 30.8 1.2 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Phostensin_N PF13916.1 AIN98548.1 - 0.058 13.3 1.8 0.92 9.5 0.8 2.4 2 0 0 2 2 2 0 PP1-regulatory protein, Phostensin N-terminal Apt1 PF10351.4 AIN98548.1 - 0.22 10.3 0.7 0.34 9.6 0.5 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain TPR_19 PF14559.1 AIN98552.1 - 0.0019 18.4 0.6 4 7.8 0.0 3.7 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.1 AIN98552.1 - 0.014 15.9 1.6 0.57 10.9 0.0 4.3 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_17 PF13431.1 AIN98552.1 - 0.043 14.0 0.1 2.8 8.3 0.0 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.1 AIN98552.1 - 0.051 13.5 2.0 0.83 9.6 0.0 3.2 4 0 0 4 4 4 0 Tetratricopeptide repeat Apc3 PF12895.2 AIN98552.1 - 0.087 12.9 1.0 19 5.4 0.0 3.5 3 0 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 ADH_zinc_N_2 PF13602.1 AIN98553.1 - 6.4e-14 52.9 0.0 2.5e-13 51.0 0.0 2.0 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 AIN98553.1 - 3e-10 39.8 0.2 1.1e-09 37.9 0.1 2.0 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 AIN98553.1 - 2.9e-08 33.3 0.1 7.8e-07 28.7 0.0 2.7 2 1 0 2 2 2 1 Zinc-binding dehydrogenase Glyco_hydro_32N PF00251.15 AIN98554.1 - 1.5e-83 280.7 0.4 2.1e-83 280.2 0.3 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 N-terminal domain Glyco_hydro_32C PF08244.7 AIN98554.1 - 1.1e-07 32.1 0.0 2.2e-07 31.1 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 C terminal Glyco_hydro_43 PF04616.9 AIN98554.1 - 3.4e-06 26.3 0.2 5e-06 25.8 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 DUF377 PF04041.8 AIN98554.1 - 0.012 14.3 0.0 2.3 6.8 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF377) BNR_2 PF13088.1 AIN98554.1 - 0.033 13.4 0.2 0.054 12.7 0.1 1.4 1 0 0 1 1 1 0 BNR repeat-like domain BON PF04972.12 AIN98554.1 - 0.11 12.3 0.0 0.18 11.5 0.0 1.3 1 0 0 1 1 1 0 BON domain Methyltransf_28 PF02636.12 AIN98555.1 - 9.9e-59 198.7 0.0 1.4e-58 198.2 0.0 1.1 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase NIF PF03031.13 AIN98556.1 - 0.012 15.2 0.1 0.034 13.8 0.0 1.7 2 0 0 2 2 2 0 NLI interacting factor-like phosphatase PRP21_like_P PF12230.3 AIN98556.1 - 0.11 12.0 0.2 0.2 11.1 0.2 1.4 1 0 0 1 1 1 0 Pre-mRNA splicing factor PRP21 like protein Peptidase_M17 PF00883.16 AIN98558.1 - 4.4e-101 337.8 0.0 5.8e-101 337.4 0.0 1.2 1 0 0 1 1 1 1 Cytosol aminopeptidase family, catalytic domain Peptidase_M17_N PF02789.12 AIN98558.1 - 0.00017 21.3 0.0 0.00052 19.7 0.0 1.8 1 0 0 1 1 1 1 Cytosol aminopeptidase family, N-terminal domain CHB_HEX_C_1 PF13290.1 AIN98559.1 - 1.5e-07 31.1 0.3 5e-05 23.0 0.1 3.0 3 0 0 3 3 3 2 Chitobiase/beta-hexosaminidase C-terminal domain CHB_HEX_C PF03174.8 AIN98559.1 - 2.9e-07 30.2 1.4 8.3e-05 22.3 0.8 3.2 3 1 0 3 3 3 1 Chitobiase/beta-hexosaminidase C-terminal domain Fn3_assoc PF13287.1 AIN98559.1 - 1.5e-06 28.2 0.1 0.0019 18.2 0.0 3.6 4 0 0 4 4 4 2 Fn3 associated DUF4381 PF14316.1 AIN98559.1 - 0.013 15.6 0.1 0.026 14.6 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) DUF4467 PF14729.1 AIN98559.1 - 0.22 11.8 0.0 0.43 10.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function with cystatin-like fold (DUF4467) TerB PF05099.8 AIN98560.1 - 0.051 13.3 0.1 0.051 13.3 0.0 2.5 3 0 0 3 3 3 0 Tellurite resistance protein TerB DUF3903 PF13043.1 AIN98561.1 - 0.088 12.3 0.5 0.17 11.3 0.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3903) PspA_IM30 PF04012.7 AIN98563.1 - 0.0056 16.0 0.3 0.0056 16.0 0.2 2.3 2 1 0 2 2 2 1 PspA/IM30 family Cut12 PF11500.3 AIN98563.1 - 0.011 15.3 3.4 0.026 14.2 2.4 1.6 1 0 0 1 1 1 0 Spindle pole body formation-associated protein Phage_Gp23 PF10669.4 AIN98563.1 - 0.25 11.4 3.7 0.5 10.4 2.6 1.5 1 0 0 1 1 1 0 Protein gp23 (Bacteriophage A118) Scaffolding_pro PF11418.3 AIN98563.1 - 0.87 9.9 7.3 0.25 11.6 1.1 2.8 2 2 0 3 3 3 0 Phi29 scaffolding protein DUF724 PF05266.9 AIN98563.1 - 4.9 6.7 10.9 1.1 8.8 3.7 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF724) Seryl_tRNA_N PF02403.17 AIN98563.1 - 7.7 6.5 11.5 5.1 7.1 3.5 2.2 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Pentapeptide_2 PF01469.13 AIN98566.1 - 0.94 9.1 54.4 0.14 11.8 6.0 4.6 1 1 3 4 4 4 0 Pentapeptide repeats (8 copies) KIAA1430 PF13879.1 AIN98567.1 - 0.00022 21.5 0.5 0.00052 20.3 0.3 1.7 1 0 0 1 1 1 1 KIAA1430 homologue 5-FTHF_cyc-lig PF01812.15 AIN98569.1 - 6e-12 45.7 1.9 2.2e-09 37.3 0.0 3.4 4 0 0 4 4 4 2 5-formyltetrahydrofolate cyclo-ligase family HIT PF01230.18 AIN98570.1 - 7.6e-12 45.6 0.1 2.6e-11 43.8 0.1 1.9 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.3 AIN98570.1 - 5.3e-06 26.6 0.2 3.9e-05 23.8 0.1 2.2 1 1 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding DUF2410 PF10307.4 AIN98571.1 - 4.8e-07 29.3 0.0 2.6e-05 23.6 0.0 2.2 2 0 0 2 2 2 2 Hypothetical protein (DUF2410) LRR_4 PF12799.2 AIN98573.1 - 2.2e-21 74.9 3.7 4.4e-05 22.9 0.0 7.6 5 1 2 7 7 7 6 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 AIN98573.1 - 1.8e-12 46.8 7.3 0.072 12.8 0.0 6.7 5 2 2 7 7 7 6 Leucine rich repeat LRR_1 PF00560.28 AIN98573.1 - 1.9e-05 24.0 10.3 1.6 9.0 0.0 8.0 7 1 0 7 7 7 1 Leucine Rich Repeat LRR_5 PF13306.1 AIN98573.1 - 0.0011 18.6 1.4 0.76 9.4 0.0 3.4 2 1 1 3 3 3 2 Leucine rich repeats (6 copies) LRR_7 PF13504.1 AIN98573.1 - 0.0016 18.2 16.3 18 6.1 0.0 8.3 9 1 0 9 9 9 2 Leucine rich repeat DUF3184 PF11380.3 AIN98574.1 - 0.0003 18.9 0.4 0.017 13.1 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF3184) CH PF00307.26 AIN98575.1 - 0.0033 17.4 0.8 0.026 14.5 0.6 2.2 1 1 0 1 1 1 1 Calponin homology (CH) domain DivIC PF04977.10 AIN98576.1 - 0.19 11.1 30.4 0.19 11.2 0.8 5.8 5 1 1 6 6 6 0 Septum formation initiator FlaC_arch PF05377.6 AIN98576.1 - 0.46 10.4 2.8 1.5 8.8 0.4 3.2 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) DUF3450 PF11932.3 AIN98576.1 - 1.2 8.4 21.3 0.024 13.9 1.6 4.3 4 0 0 4 4 4 0 Protein of unknown function (DUF3450) CENP-F_leu_zip PF10473.4 AIN98576.1 - 1.6 8.5 40.9 0.02 14.7 3.3 5.5 4 1 1 5 5 5 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF972 PF06156.8 AIN98576.1 - 2 8.8 21.9 0.42 10.9 0.5 4.9 5 0 0 5 5 5 0 Protein of unknown function (DUF972) Pox_A_type_inc PF04508.7 AIN98576.1 - 7.2 6.6 8.5 35 4.5 0.0 4.4 4 0 0 4 4 4 0 Viral A-type inclusion protein repeat HALZ PF02183.13 AIN98577.1 - 0.072 12.8 23.1 3 7.6 0.2 7.4 7 0 0 7 7 7 0 Homeobox associated leucine zipper DUF3138 PF11336.3 AIN98577.1 - 0.37 8.9 3.6 0.52 8.4 1.6 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3138) DUF87 PF01935.12 AIN98578.1 - 2.4 7.8 8.8 6.3 6.5 0.4 2.6 2 1 1 3 3 3 0 Domain of unknown function DUF87 DUF1900 PF08954.6 AIN98580.1 - 2.9e-39 133.6 0.0 5e-39 132.9 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1900) WD40 PF00400.27 AIN98580.1 - 1.3e-12 47.1 1.1 0.00012 21.8 0.1 4.1 4 0 0 4 4 4 3 WD domain, G-beta repeat DUF1899 PF08953.6 AIN98580.1 - 2e-07 30.5 0.0 4.2e-07 29.4 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1899) Ribosomal_S9 PF00380.14 AIN98581.1 - 6.5e-05 23.1 0.0 0.00012 22.2 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein S9/S16 UPF0546 PF10639.4 AIN98582.1 - 6.3e-37 125.8 1.1 7.3e-37 125.6 0.8 1.0 1 0 0 1 1 1 1 Uncharacterised protein family UPF0546 EamA PF00892.15 AIN98582.1 - 2e-05 24.6 1.9 2e-05 24.6 1.3 1.6 2 0 0 2 2 2 1 EamA-like transporter family Herpes_LMP1 PF05297.6 AIN98582.1 - 0.0045 15.9 1.1 0.0045 15.9 0.7 1.4 2 0 0 2 2 2 1 Herpesvirus latent membrane protein 1 (LMP1) His_Phos_2 PF00328.17 AIN98583.1 - 4.1e-24 85.5 0.0 2.3e-23 83.0 0.0 1.8 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Methyltransf_5 PF01795.14 AIN98584.1 - 1.7e-27 96.5 0.0 2.4e-27 96.0 0.0 1.1 1 0 0 1 1 1 1 MraW methylase family Methyltransf_26 PF13659.1 AIN98584.1 - 3.3e-05 23.8 0.0 0.00017 21.6 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 AIN98584.1 - 4.4e-05 23.1 0.0 0.00087 18.9 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.9 AIN98584.1 - 0.0044 16.4 0.0 0.042 13.2 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_18 PF12847.2 AIN98584.1 - 0.0067 16.9 0.0 0.16 12.5 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain SIR2 PF02146.12 AIN98585.1 - 8.7e-35 120.0 0.0 1.6e-33 115.8 0.0 2.1 1 1 0 1 1 1 1 Sir2 family Cpn60_TCP1 PF00118.19 AIN98586.1 - 1.2e-148 495.7 2.6 1.5e-148 495.4 1.8 1.1 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Spore_coat_CotO PF14153.1 AIN98587.1 - 0.057 12.8 0.3 0.067 12.6 0.2 1.1 1 0 0 1 1 1 0 Spore coat protein CotO PPR_2 PF13041.1 AIN98588.1 - 8.2e-06 25.6 0.0 2.7e-05 24.0 0.0 2.0 2 0 0 2 2 2 1 PPR repeat family PPR_1 PF12854.2 AIN98588.1 - 0.00011 21.5 0.0 0.00024 20.4 0.0 1.6 1 0 0 1 1 1 1 PPR repeat PPR_3 PF13812.1 AIN98588.1 - 0.00086 19.4 0.0 0.0042 17.2 0.0 2.3 1 0 0 1 1 1 1 Pentatricopeptide repeat domain PPR PF01535.15 AIN98588.1 - 0.0022 17.8 0.6 0.0065 16.3 0.1 2.1 2 0 0 2 2 2 1 PPR repeat DUF3250 PF11618.3 AIN98589.1 - 8.6e-24 83.8 1.5 8.6e-24 83.8 1.0 3.5 4 1 1 5 5 5 1 Protein of unknown function (DUF3250) Macoilin PF09726.4 AIN98589.1 - 0.0051 15.1 0.8 0.0051 15.1 0.5 3.7 3 1 1 4 4 4 1 Transmembrane protein DUF2968 PF11180.3 AIN98589.1 - 0.0056 16.0 11.3 0.0056 16.0 7.8 4.7 2 1 3 5 5 5 1 Protein of unknown function (DUF2968) KNOX2 PF03791.8 AIN98589.1 - 0.035 13.3 0.2 0.13 11.5 0.2 2.0 1 0 0 1 1 1 0 KNOX2 domain GAS PF13851.1 AIN98589.1 - 1 8.5 27.1 1.8 7.7 4.4 3.4 3 0 0 3 3 3 0 Growth-arrest specific micro-tubule binding DUF972 PF06156.8 AIN98589.1 - 3.1 8.1 25.5 1.8 8.9 0.2 4.7 2 1 1 4 4 4 0 Protein of unknown function (DUF972) RICTOR_M PF14666.1 AIN98590.1 - 1.7e-52 177.7 0.0 8.2e-52 175.4 0.0 2.1 2 0 0 2 2 2 1 Rapamycin-insensitive companion of mTOR, middle domain RICTOR_N PF14664.1 AIN98590.1 - 1.3e-15 56.8 1.9 1.3e-13 50.3 0.0 2.7 3 0 0 3 3 3 2 Rapamycin-insensitive companion of mTOR, N-term RasGEF_N_2 PF14663.1 AIN98590.1 - 2.5e-08 33.8 0.4 1.2e-07 31.6 0.3 2.3 1 0 0 1 1 1 1 Rapamycin-insensitive companion of mTOR RasGEF_N domain RICTOR_V PF14668.1 AIN98590.1 - 0.00045 20.1 0.2 0.0046 16.8 0.1 2.9 3 0 0 3 3 3 1 Rapamycin-insensitive companion of mTOR, domain 5 DUF3602 PF12223.3 AIN98590.1 - 0.14 12.5 0.1 0.14 12.5 0.0 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3602) XPG_I PF00867.13 AIN98592.1 - 4.5e-21 74.7 0.1 1.4e-18 66.7 0.0 2.5 2 0 0 2 2 2 2 XPG I-region XPG_N PF00752.12 AIN98592.1 - 6.3e-15 55.2 0.0 2.6e-06 27.6 0.0 2.5 2 0 0 2 2 2 2 XPG N-terminal domain FA_hydroxylase PF04116.8 AIN98595.1 - 7.6e-14 52.0 20.3 7.6e-14 52.0 14.1 2.7 3 0 0 3 3 3 1 Fatty acid hydroxylase superfamily Dynein_heavy PF03028.10 AIN98596.1 - 6.8e-198 659.0 0.0 1.8e-197 657.6 0.0 1.8 1 0 0 1 1 1 1 Dynein heavy chain and region D6 of dynein motor DHC_N2 PF08393.8 AIN98596.1 - 5.6e-125 417.0 8.6 5.6e-125 417.0 6.0 3.9 4 0 0 4 4 4 1 Dynein heavy chain, N-terminal region 2 AAA_6 PF12774.2 AIN98596.1 - 8.3e-96 319.9 0.0 1.9e-95 318.8 0.0 1.6 1 0 0 1 1 1 1 Hydrolytic ATP binding site of dynein motor region D1 DHC_N1 PF08385.7 AIN98596.1 - 1.5e-78 264.6 4.9 5e-78 262.9 0.0 4.0 3 2 0 3 3 2 1 Dynein heavy chain, N-terminal region 1 AAA_8 PF12780.2 AIN98596.1 - 3.5e-67 226.1 0.0 9.3e-67 224.8 0.0 1.7 2 0 0 2 2 2 1 P-loop containing dynein motor region D4 AAA_9 PF12781.2 AIN98596.1 - 3.2e-54 183.1 0.9 2.6e-52 176.9 0.2 2.5 2 0 0 2 2 2 1 ATP-binding dynein motor region D5 AAA_7 PF12775.2 AIN98596.1 - 1.1e-47 162.4 0.0 3.3e-47 160.8 0.0 1.9 1 0 0 1 1 1 1 P-loop containing dynein motor region D3 MT PF12777.2 AIN98596.1 - 5.9e-40 137.0 14.4 1.4e-39 135.8 10.0 1.5 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_5 PF07728.9 AIN98596.1 - 2.1e-25 89.0 0.2 1.1e-07 31.6 0.0 6.2 5 1 0 5 5 5 4 AAA domain (dynein-related subfamily) AAA PF00004.24 AIN98596.1 - 3.9e-05 23.8 0.0 0.36 11.0 0.0 4.1 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 AIN98596.1 - 0.008 16.9 0.3 8.1 7.2 0.0 5.0 4 0 0 4 4 4 1 AAA domain ABC_tran PF00005.22 AIN98596.1 - 0.02 15.1 1.0 9.9 6.4 0.0 4.5 4 0 0 4 4 4 0 ABC transporter AAA_19 PF13245.1 AIN98596.1 - 0.063 13.0 6.0 3.7 7.3 0.4 3.7 3 0 0 3 3 3 0 Part of AAA domain RNA_helicase PF00910.17 AIN98596.1 - 0.11 12.6 0.0 44 4.3 0.0 3.5 3 0 0 3 3 3 0 RNA helicase AAA_22 PF13401.1 AIN98596.1 - 1.5 8.9 17.6 4.6 7.3 0.0 6.5 8 0 0 8 8 6 0 AAA domain SBP_bac_1 PF01547.20 AIN98596.1 - 4.4 6.9 0.1 8.2 6.0 0.0 1.3 1 0 0 1 1 1 0 Bacterial extracellular solute-binding protein YceI PF04264.8 AIN98597.1 - 1.7e-10 41.1 0.0 1.9e-10 40.9 0.0 1.2 1 0 0 1 1 1 1 YceI-like domain DNA_pol_B PF00136.16 AIN98598.1 - 2.2e-73 247.6 0.0 3.2e-73 247.1 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.14 AIN98598.1 - 9.6e-05 21.3 0.0 0.042 12.6 0.0 2.3 2 0 0 2 2 2 2 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.1 AIN98598.1 - 0.0002 21.3 0.4 0.00096 19.1 0.1 2.3 2 0 0 2 2 2 1 C4-type zinc-finger of DNA polymerase delta Radical_SAM PF04055.16 AIN98600.1 - 3e-14 53.5 0.0 8e-14 52.1 0.0 1.8 1 0 0 1 1 1 1 Radical SAM superfamily Acetyltransf_1 PF00583.19 AIN98600.1 - 1.5e-08 34.5 0.5 4.2e-08 33.0 0.4 1.8 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Hum_adeno_E3A PF05393.6 AIN98601.1 - 0.03 14.0 0.1 0.056 13.1 0.1 1.4 1 0 0 1 1 1 0 Human adenovirus early E3A glycoprotein Mito_carr PF00153.22 AIN98602.1 - 4.4e-39 132.0 2.9 8.5e-17 60.6 0.0 3.4 3 1 0 3 3 3 3 Mitochondrial carrier protein Helicase_C PF00271.26 AIN98603.1 - 3.5e-12 46.0 0.0 7.4e-12 44.9 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 AIN98603.1 - 9e-12 44.8 0.0 1.3e-10 41.0 0.0 2.4 1 1 0 1 1 1 1 DEAD/DEAH box helicase HHH_5 PF14520.1 AIN98603.1 - 0.0009 19.3 0.0 0.0024 18.0 0.0 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix domain CMS1 PF14617.1 AIN98603.1 - 0.67 8.9 0.6 1.2 8.1 0.4 1.3 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit MtrD PF04207.7 AIN98604.1 - 0.0061 15.9 0.2 0.011 15.1 0.0 1.4 1 1 1 2 2 2 1 Tetrahydromethanopterin S-methyltransferase, subunit D Cg6151-P PF10233.4 AIN98604.1 - 0.95 9.4 4.7 1.3 9.0 3.3 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein CG6151-P CTP_transf_1 PF01148.15 AIN98604.1 - 6 6.4 7.3 11 5.5 5.1 1.4 1 1 0 1 1 1 0 Cytidylyltransferase family Mog1 PF04603.7 AIN98605.1 - 2.6e-23 82.5 0.0 3e-17 62.8 0.0 2.1 1 1 1 2 2 2 2 Ran-interacting Mog1 protein Fer2_3 PF13085.1 AIN98606.1 - 7.3e-31 106.2 0.1 3.7e-30 103.9 0.0 2.0 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain EzrA PF06160.7 AIN98606.1 - 0.0057 14.8 0.2 0.0076 14.4 0.1 1.1 1 0 0 1 1 1 1 Septation ring formation regulator, EzrA Fer2 PF00111.22 AIN98606.1 - 0.01 15.5 0.7 0.01 15.5 0.5 2.0 2 0 0 2 2 2 0 2Fe-2S iron-sulfur cluster binding domain TPR_21 PF09976.4 AIN98606.1 - 0.027 14.4 0.5 0.027 14.4 0.4 1.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.1 AIN98606.1 - 0.064 13.9 0.3 0.23 12.2 0.2 2.0 1 1 0 1 1 1 0 Tetratricopeptide repeat DUF3412 PF11892.3 AIN98606.1 - 0.13 12.1 0.2 0.26 11.0 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3412) PPR_3 PF13812.1 AIN98606.1 - 0.16 12.3 1.2 1.4 9.3 0.0 2.7 2 0 0 2 2 2 0 Pentatricopeptide repeat domain zf-DHHC PF01529.15 AIN98607.1 - 1e-36 125.9 9.8 1e-36 125.9 6.8 1.8 1 1 1 2 2 2 1 DHHC palmitoyltransferase zf-DHHC PF01529.15 AIN98608.1 - 1.1e-35 122.6 0.7 1.1e-35 122.6 0.5 2.0 2 1 0 2 2 2 1 DHHC palmitoyltransferase zf-DHHC PF01529.15 AIN98609.1 - 4.9e-23 81.4 24.0 4.9e-23 81.4 16.7 2.3 1 1 1 2 2 2 1 DHHC palmitoyltransferase PTPlike_phytase PF14566.1 AIN98610.1 - 1.4e-109 362.6 0.5 1.2e-41 142.2 0.0 3.6 3 0 0 3 3 3 3 Inositol hexakisphosphate Y_phosphatase3 PF13350.1 AIN98610.1 - 0.0011 19.2 1.3 3.1 8.0 0.0 3.5 4 0 0 4 4 4 2 Tyrosine phosphatase family Y_phosphatase PF00102.22 AIN98610.1 - 0.14 11.4 0.0 15 4.8 0.0 3.0 3 0 0 3 3 3 0 Protein-tyrosine phosphatase PASTA PF03793.14 AIN98610.1 - 0.17 11.5 0.0 0.35 10.5 0.0 1.5 1 0 0 1 1 1 0 PASTA domain ADK PF00406.17 AIN98611.1 - 2.3e-07 30.7 0.1 0.00052 19.9 0.0 3.0 3 0 0 3 3 3 2 Adenylate kinase AAA PF00004.24 AIN98611.1 - 0.0053 16.9 0.2 0.24 11.5 0.1 2.4 1 1 1 2 2 2 1 ATPase family associated with various cellular activities (AAA) Zeta_toxin PF06414.7 AIN98611.1 - 0.01 14.9 0.1 0.03 13.4 0.0 1.8 1 1 0 1 1 1 0 Zeta toxin AAA_33 PF13671.1 AIN98611.1 - 0.011 15.6 0.2 0.035 13.9 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.1 AIN98611.1 - 0.06 12.7 0.1 0.13 11.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain SurA_N PF09312.6 AIN98611.1 - 0.064 13.1 0.5 0.63 9.9 0.0 2.1 2 0 0 2 2 2 0 SurA N-terminal domain AAA_17 PF13207.1 AIN98611.1 - 0.071 13.9 0.0 0.15 12.8 0.0 1.7 1 1 0 1 1 1 0 AAA domain Phe_hydrox_dim PF07976.7 AIN98611.1 - 0.083 12.5 0.0 0.15 11.6 0.0 1.4 1 0 0 1 1 1 0 Phenol hydroxylase, C-terminal dimerisation domain AAA_5 PF07728.9 AIN98611.1 - 0.12 12.1 0.0 0.23 11.1 0.0 1.6 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 AIN98611.1 - 0.36 10.7 5.0 0.33 10.9 0.2 2.8 2 1 1 3 3 3 0 AAA ATPase domain Methyltransf_26 PF13659.1 AIN98612.1 - 0.0061 16.5 0.0 0.011 15.7 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain GLTSCR1 PF15249.1 AIN98613.1 - 0.1 12.7 0.1 0.11 12.5 0.1 1.2 1 0 0 1 1 1 0 Glioma tumor suppressor candidate region zf-rbx1 PF12678.2 AIN98615.1 - 1.9e-13 50.2 5.3 3.3e-13 49.5 3.7 1.3 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_2 PF13639.1 AIN98615.1 - 3.2e-10 39.6 9.6 3e-09 36.5 6.7 2.2 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 AIN98615.1 - 2.5e-06 27.3 7.9 1.2e-05 25.2 3.5 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 AIN98615.1 - 1.2e-05 24.8 6.2 2.1e-05 24.1 3.8 1.7 1 1 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 AIN98615.1 - 1.7e-05 24.3 7.5 3.8e-05 23.2 5.2 1.6 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 AIN98615.1 - 4.4e-05 23.2 3.9 0.0001 22.0 2.7 1.6 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.1 AIN98615.1 - 0.00044 19.8 9.9 0.0015 18.1 6.0 2.0 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-Nse PF11789.3 AIN98615.1 - 0.071 12.6 2.1 0.17 11.4 1.5 1.6 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit DUF572 PF04502.8 AIN98615.1 - 0.18 10.9 0.4 0.34 10.0 0.3 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF572) FANCL_C PF11793.3 AIN98615.1 - 0.42 10.6 7.7 4.9 7.1 5.3 2.5 1 1 1 2 2 2 0 FANCL C-terminal domain zf-P11 PF03854.9 AIN98615.1 - 0.64 9.5 5.3 0.32 10.4 2.0 1.7 2 0 0 2 2 2 0 P-11 zinc finger zf-RING_UBOX PF13445.1 AIN98615.1 - 2.8 7.7 7.7 2.8 7.7 2.8 2.8 1 1 1 2 2 2 0 RING-type zinc-finger RINGv PF12906.2 AIN98615.1 - 4.3 7.4 8.6 0.8 9.7 2.8 2.0 2 0 0 2 2 2 0 RING-variant domain V-SNARE PF05008.10 AIN98616.1 - 6.5e-10 39.0 0.6 2e-07 31.0 0.0 3.0 4 0 0 4 4 4 1 Vesicle transport v-SNARE protein N-terminus Sec20 PF03908.8 AIN98616.1 - 9.8e-07 28.3 0.8 6.3e-06 25.8 0.2 2.3 2 0 0 2 2 2 1 Sec20 V-SNARE_C PF12352.3 AIN98616.1 - 6.5e-06 26.1 1.9 6.5e-06 26.1 1.3 1.7 2 0 0 2 2 2 1 Snare region anchored in the vesicle membrane C-terminus Syntaxin-6_N PF09177.6 AIN98616.1 - 0.0074 16.6 3.1 0.084 13.2 0.1 3.1 2 1 1 3 3 3 1 Syntaxin 6, N-terminal Laminin_I PF06008.9 AIN98616.1 - 0.015 14.6 5.0 0.24 10.6 1.5 2.3 2 0 0 2 2 2 0 Laminin Domain I DASH_Duo1 PF08651.5 AIN98616.1 - 0.026 14.0 1.9 6.1 6.5 0.1 3.0 3 1 1 4 4 4 0 DASH complex subunit Duo1 Mnd1 PF03962.10 AIN98616.1 - 0.044 13.4 1.9 0.23 11.1 0.0 2.1 2 0 0 2 2 2 0 Mnd1 family Vps51 PF08700.6 AIN98616.1 - 0.066 13.0 2.3 4.7 7.1 0.0 3.7 4 1 1 5 5 5 0 Vps51/Vps67 DUF2077 PF09850.4 AIN98616.1 - 0.085 12.2 3.2 0.29 10.5 0.1 2.3 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2077) DUF3391 PF11871.3 AIN98616.1 - 0.21 11.8 3.9 0.62 10.2 0.2 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF3391) DUF3753 PF12575.3 AIN98616.1 - 0.74 9.6 4.2 0.35 10.6 0.6 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3753) Fez1 PF06818.10 AIN98616.1 - 2.4 8.1 8.2 3.7 7.5 3.3 2.5 2 1 1 3 3 3 0 Fez1 Filament PF00038.16 AIN98616.1 - 7.6 5.8 7.9 2.5 7.4 0.5 2.4 3 0 0 3 3 3 0 Intermediate filament protein V-SNARE PF05008.10 AIN98617.1 - 1.1e-11 44.7 1.8 5.5e-11 42.4 0.0 2.8 2 1 1 3 3 3 1 Vesicle transport v-SNARE protein N-terminus V-SNARE_C PF12352.3 AIN98617.1 - 3.7e-07 30.1 0.7 7.9e-07 29.0 0.5 1.5 1 0 0 1 1 1 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.8 AIN98617.1 - 5.8e-06 25.9 1.9 1.1e-05 25.0 0.8 1.8 2 0 0 2 2 2 1 Sec20 CCDC155 PF14662.1 AIN98617.1 - 0.0024 17.5 6.9 0.11 12.0 1.1 2.3 2 0 0 2 2 2 2 Coiled-coil region of CCDC155 Synaptobrevin PF00957.16 AIN98617.1 - 0.0072 15.9 1.4 0.019 14.5 1.0 1.8 1 0 0 1 1 1 1 Synaptobrevin Unstab_antitox PF09720.5 AIN98617.1 - 0.011 15.4 0.3 0.061 13.0 0.0 2.3 2 0 0 2 2 2 0 Putative addiction module component TMEM154 PF15102.1 AIN98617.1 - 0.019 14.6 2.1 0.033 13.8 1.5 1.3 1 0 0 1 1 1 0 TMEM154 protein family Spc7 PF08317.6 AIN98617.1 - 0.035 12.7 3.3 0.052 12.1 2.3 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein ATP-synt_8 PF00895.15 AIN98617.1 - 0.047 13.9 0.1 0.088 13.0 0.1 1.4 1 0 0 1 1 1 0 ATP synthase protein 8 DUF2142 PF09913.4 AIN98617.1 - 0.12 11.0 0.5 0.17 10.4 0.3 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2142) DUF745 PF05335.8 AIN98617.1 - 0.17 11.3 7.1 10 5.5 4.0 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF745) DUF883 PF05957.8 AIN98617.1 - 0.64 10.4 12.4 0.99 9.8 0.7 3.3 2 1 0 3 3 3 0 Bacterial protein of unknown function (DUF883) OapA_N PF08525.6 AIN98617.1 - 2.3 8.1 5.9 28 4.6 4.3 2.4 2 0 0 2 2 2 0 Opacity-associated protein A N-terminal motif BRCT PF00533.21 AIN98618.1 - 0.0079 16.3 0.0 0.02 15.0 0.0 1.7 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain EXOSC1 PF10447.4 AIN98619.1 - 2e-10 40.4 0.0 3.9e-10 39.5 0.0 1.5 1 0 0 1 1 1 1 Exosome component EXOSC1/CSL4 Trichoplein PF13868.1 AIN98621.1 - 4.1e-12 45.1 126.4 4.1e-12 45.1 87.6 2.3 2 1 0 2 2 2 1 Tumour suppressor, Mitostatin DUF1816 PF08846.5 AIN98621.1 - 1.4 8.6 5.1 1.9 8.2 1.5 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF1816) Semialdhyde_dh PF01118.19 AIN98621.1 - 9.6 6.5 7.0 2.8 8.2 1.1 2.5 2 1 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain TIP41 PF04176.8 AIN98622.1 - 5.3e-18 64.9 0.0 1.1e-17 63.8 0.0 1.5 1 0 0 1 1 1 1 TIP41-like family GAF_2 PF13185.1 AIN98622.1 - 1.1e-06 29.2 0.0 1.7e-06 28.5 0.0 1.3 1 0 0 1 1 1 1 GAF domain GAF PF01590.21 AIN98622.1 - 2.2e-06 27.8 0.0 4.1e-06 26.9 0.0 1.4 1 0 0 1 1 1 1 GAF domain GAF_3 PF13492.1 AIN98622.1 - 0.00062 19.8 0.0 0.0013 18.8 0.0 1.5 1 0 0 1 1 1 1 GAF domain LRR_4 PF12799.2 AIN98623.1 - 2.8e-06 26.8 0.3 0.012 15.1 0.0 2.8 3 0 0 3 3 3 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 AIN98623.1 - 0.0019 17.9 3.0 1.2 8.9 0.0 2.5 2 1 0 2 2 2 2 Leucine rich repeat LRR_6 PF13516.1 AIN98623.1 - 0.035 14.1 0.2 5 7.5 0.0 3.5 4 0 0 4 4 4 0 Leucine Rich repeat LRR_9 PF14580.1 AIN98623.1 - 0.081 12.4 0.0 0.12 11.9 0.0 1.2 1 0 0 1 1 1 0 Leucine-rich repeat DUF2183 PF09949.4 AIN98623.1 - 0.12 12.2 0.0 0.28 11.1 0.0 1.6 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2183) LRR_7 PF13504.1 AIN98623.1 - 0.17 12.1 2.4 12 6.6 0.0 3.9 3 1 1 4 4 4 0 Leucine rich repeat Nop14 PF04147.7 AIN98623.1 - 1.3 6.8 11.9 1.5 6.6 8.2 1.1 1 0 0 1 1 1 0 Nop14-like family Ala_racemase_N PF01168.15 AIN98624.1 - 1.2e-41 142.6 0.0 1.4e-41 142.4 0.0 1.0 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain LRR_8 PF13855.1 AIN98625.1 - 6.6e-10 38.5 4.0 0.32 10.7 0.3 5.0 3 3 0 4 4 4 4 Leucine rich repeat LRR_1 PF00560.28 AIN98625.1 - 5.1e-08 31.8 3.1 0.34 11.0 0.1 5.0 4 1 0 4 4 4 3 Leucine Rich Repeat LRR_4 PF12799.2 AIN98625.1 - 7.1e-08 31.9 5.7 0.047 13.3 0.0 4.7 3 2 2 5 5 5 3 Leucine Rich repeats (2 copies) LRR_6 PF13516.1 AIN98625.1 - 3.9e-06 26.3 5.1 0.68 10.1 0.1 4.7 5 0 0 5 5 5 3 Leucine Rich repeat LRR_7 PF13504.1 AIN98625.1 - 0.0035 17.2 7.3 3.8 8.1 0.2 5.1 5 1 0 5 5 5 2 Leucine rich repeat GCIP PF13324.1 AIN98626.1 - 0.13 11.5 0.1 0.26 10.4 0.0 1.4 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting V_ATPase_I PF01496.14 AIN98627.1 - 1.9e-214 713.8 13.7 3.8e-197 656.6 3.2 2.0 1 1 1 2 2 2 2 V-type ATPase 116kDa subunit family DUF972 PF06156.8 AIN98627.1 - 0.11 12.9 1.2 0.55 10.5 0.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF972) DegS PF05384.6 AIN98627.1 - 1.4 8.1 6.3 4.4 6.4 0.4 2.6 2 1 1 3 3 3 0 Sensor protein DegS UbiA PF01040.13 AIN98628.1 - 6.8e-29 100.8 21.6 1e-28 100.2 15.0 1.3 1 1 0 1 1 1 1 UbiA prenyltransferase family Myosin_tail_1 PF01576.14 AIN98629.1 - 0.051 11.3 0.4 0.069 10.8 0.2 1.0 1 0 0 1 1 1 0 Myosin tail ARL6IP6 PF15062.1 AIN98629.1 - 0.085 12.7 0.1 0.65 9.9 0.0 2.5 2 0 0 2 2 2 0 Haemopoietic lineage transmembrane helix NRDE-2 PF08424.5 AIN98631.1 - 4.6e-06 25.7 0.8 0.0031 16.4 0.1 3.4 2 1 1 3 3 3 3 NRDE-2, necessary for RNA interference TPR_19 PF14559.1 AIN98631.1 - 0.28 11.5 6.1 8.7 6.7 0.0 5.6 6 0 0 6 6 6 0 Tetratricopeptide repeat Beach PF02138.13 AIN98633.1 - 3.1e-85 285.8 0.0 4.2e-85 285.4 0.0 1.2 1 0 0 1 1 1 1 Beige/BEACH domain Nuc_deoxyrib_tr PF05014.10 AIN98634.1 - 1.2e-28 99.2 0.0 1.6e-28 98.7 0.0 1.2 1 0 0 1 1 1 1 Nucleoside 2-deoxyribosyltransferase DUF4406 PF14359.1 AIN98634.1 - 0.001 19.0 0.0 0.0016 18.4 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4406) Histone PF00125.19 AIN98635.1 - 4.1e-13 49.2 0.4 5.6e-13 48.8 0.3 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 AIN98635.1 - 0.00012 22.0 0.3 0.00036 20.5 0.0 1.8 2 1 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TAF PF02969.12 AIN98635.1 - 0.00055 19.8 0.1 0.001 18.9 0.1 1.5 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) Bromo_TP PF07524.8 AIN98635.1 - 0.0021 17.7 0.0 0.0034 17.0 0.0 1.4 1 0 0 1 1 1 1 Bromodomain associated TFIID-31kDa PF02291.10 AIN98635.1 - 0.0059 16.3 0.0 0.0067 16.2 0.0 1.2 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit BCDHK_Adom3 PF10436.4 AIN98636.1 - 1.8e-34 118.6 0.0 3.6e-34 117.6 0.0 1.5 1 1 1 2 2 2 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.21 AIN98636.1 - 0.03 14.0 0.0 0.083 12.6 0.0 1.8 1 1 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase FerB PF08150.7 AIN98636.1 - 0.082 12.9 0.0 1.5 8.9 0.0 2.3 2 0 0 2 2 2 0 FerB (NUC096) domain ANTH PF07651.11 AIN98637.1 - 1.1e-24 86.6 0.1 1.6e-24 86.1 0.0 1.3 1 0 0 1 1 1 1 ANTH domain ENTH PF01417.15 AIN98637.1 - 0.00064 19.5 0.1 0.0012 18.7 0.0 1.4 1 0 0 1 1 1 1 ENTH domain DUF3886 PF13025.1 AIN98638.1 - 0.018 14.9 1.4 0.029 14.3 0.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3886) Ribosomal_L22 PF00237.14 AIN98639.1 - 9.6e-31 105.8 0.2 1.2e-30 105.5 0.2 1.1 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e Preseq_ALAS PF09029.5 AIN98640.1 - 0.031 14.2 0.2 9.9 6.2 0.0 2.5 2 0 0 2 2 2 0 5-aminolevulinate synthase presequence DnaJ PF00226.26 AIN98642.1 - 0.023 14.4 0.0 0.072 12.8 0.0 1.8 1 0 0 1 1 1 0 DnaJ domain zf-RING_2 PF13639.1 AIN98643.1 - 1.4e-09 37.6 5.9 1.4e-09 37.6 4.1 4.5 4 1 0 4 4 4 1 Ring finger domain zf-C3HC4_2 PF13923.1 AIN98643.1 - 7.9e-05 22.5 2.3 7.9e-05 22.5 1.6 4.5 4 2 1 5 5 5 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 AIN98643.1 - 9.4e-05 21.9 1.7 9.4e-05 21.9 1.2 4.0 3 1 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 AIN98643.1 - 0.00032 20.7 1.1 0.00032 20.7 0.7 3.8 2 1 0 2 2 2 1 RING-H2 zinc finger zf-RING_5 PF14634.1 AIN98643.1 - 0.00075 19.1 4.9 0.00075 19.1 3.4 4.7 4 1 1 5 5 5 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 AIN98643.1 - 0.0068 16.0 0.4 0.023 14.4 0.3 2.0 1 0 0 1 1 1 1 RING-type zinc-finger DUF3592 PF12158.3 AIN98644.1 - 5.2e-06 26.3 0.1 6.9e-06 25.9 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3592) Enkurin PF13864.1 AIN98645.1 - 6.6e-20 71.1 0.7 9.2e-20 70.6 0.5 1.2 1 0 0 1 1 1 1 Calmodulin-binding DUF3367 PF11847.3 AIN98645.1 - 0.11 10.4 0.0 0.15 10.0 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3367) PARP_regulatory PF01358.13 AIN98646.1 - 4.1e-16 58.4 0.0 6.1e-16 57.9 0.0 1.2 1 0 0 1 1 1 1 Poly A polymerase regulatory subunit UPF0182 PF03699.8 AIN98646.1 - 0.049 11.5 0.0 0.07 11.0 0.0 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0182) WD40 PF00400.27 AIN98647.1 - 6.8e-10 38.4 18.9 0.0011 18.7 0.4 5.0 5 1 1 6 6 6 4 WD domain, G-beta repeat Ank_2 PF12796.2 AIN98648.1 - 1.5e-60 201.5 14.8 2.4e-18 66.2 0.2 3.7 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.25 AIN98648.1 - 1.9e-46 153.5 8.0 4.3e-10 38.8 0.0 7.3 7 0 0 7 7 7 7 Ankyrin repeat Ank_5 PF13857.1 AIN98648.1 - 6.8e-37 124.6 7.1 1.9e-11 43.7 0.0 5.2 2 1 3 5 5 5 5 Ankyrin repeats (many copies) Ank_4 PF13637.1 AIN98648.1 - 1e-32 111.8 3.0 2.3e-08 34.3 0.0 4.7 3 1 2 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.1 AIN98648.1 - 2.8e-29 98.2 6.7 0.00017 21.5 0.0 7.5 8 0 0 8 8 7 6 Ankyrin repeat TPR_11 PF13414.1 AIN98648.1 - 1.6e-19 69.2 5.5 1.6e-15 56.5 0.8 2.5 1 1 1 2 2 2 2 TPR repeat TPR_1 PF00515.23 AIN98648.1 - 5.1e-11 41.6 1.5 0.0057 16.2 0.0 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.12 AIN98648.1 - 3.1e-08 32.9 1.4 0.16 11.9 0.0 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_17 PF13431.1 AIN98648.1 - 1.4e-05 24.8 1.7 0.08 13.1 0.2 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat Apc3 PF12895.2 AIN98648.1 - 0.00012 22.1 1.4 0.00028 20.9 1.0 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.1 AIN98648.1 - 0.0023 17.7 0.1 0.17 11.7 0.0 2.5 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.1 AIN98648.1 - 0.063 13.6 0.3 7.7 6.9 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_16 PF13432.1 AIN98648.1 - 0.094 13.4 1.4 5.6 7.7 0.0 2.9 3 0 0 3 3 2 0 Tetratricopeptide repeat PEX11 PF05648.9 AIN98649.1 - 1e-10 41.2 2.4 3.2e-07 29.8 0.0 2.1 1 1 1 2 2 2 2 Peroxisomal biogenesis factor 11 (PEX11) AcetylCoA_hyd_C PF13336.1 AIN98649.1 - 0.0073 15.9 0.5 0.86 9.2 0.1 2.2 2 0 0 2 2 2 2 Acetyl-CoA hydrolase/transferase C-terminal domain Phosducin PF02114.11 AIN98651.1 - 1.7e-07 30.2 0.0 2e-07 29.9 0.0 1.1 1 0 0 1 1 1 1 Phosducin Pertus-S5-tox PF09276.5 AIN98651.1 - 0.069 13.1 0.0 0.15 12.0 0.0 1.5 1 0 0 1 1 1 0 Pertussis toxin S5 subunit AAA PF00004.24 AIN98652.1 - 3.4e-31 108.1 0.0 8.2e-27 93.9 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 AIN98652.1 - 4.3e-12 46.2 0.0 0.00021 21.4 0.0 2.9 2 1 0 2 2 2 2 AAA domain NACHT PF05729.7 AIN98652.1 - 4.6e-10 39.4 0.1 3.3e-05 23.6 0.0 2.9 3 1 0 3 3 3 2 NACHT domain AAA_16 PF13191.1 AIN98652.1 - 1.7e-08 34.7 16.0 7.3e-05 22.8 0.8 4.5 2 2 1 3 3 3 2 AAA ATPase domain AAA_5 PF07728.9 AIN98652.1 - 9.4e-07 28.6 0.0 0.00025 20.8 0.0 2.8 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_33 PF13671.1 AIN98652.1 - 2.4e-06 27.4 0.0 0.0073 16.1 0.0 2.5 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.17 AIN98652.1 - 2.6e-06 27.5 0.0 0.002 18.2 0.0 2.5 2 0 0 2 2 2 1 RNA helicase DUF258 PF03193.11 AIN98652.1 - 8.5e-06 25.0 0.1 0.012 14.8 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_29 PF13555.1 AIN98652.1 - 2.7e-05 23.5 2.4 0.036 13.6 0.1 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_17 PF13207.1 AIN98652.1 - 3.3e-05 24.6 0.1 0.0041 17.9 0.0 2.5 2 0 0 2 2 2 1 AAA domain ABC_tran PF00005.22 AIN98652.1 - 4.5e-05 23.7 0.7 0.13 12.5 0.0 2.4 2 0 0 2 2 2 2 ABC transporter DUF815 PF05673.8 AIN98652.1 - 5.9e-05 22.1 0.0 0.043 12.7 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF815) AAA_25 PF13481.1 AIN98652.1 - 5.9e-05 22.5 0.1 0.062 12.7 0.0 2.5 2 0 0 2 2 2 2 AAA domain Zeta_toxin PF06414.7 AIN98652.1 - 0.00016 20.8 0.1 0.2 10.7 0.0 2.3 2 0 0 2 2 2 2 Zeta toxin AAA_28 PF13521.1 AIN98652.1 - 0.00022 21.1 0.0 0.016 15.1 0.0 2.3 2 0 0 2 2 2 1 AAA domain Arch_ATPase PF01637.13 AIN98652.1 - 0.00027 20.6 0.0 0.1 12.2 0.0 2.7 3 0 0 3 3 3 1 Archaeal ATPase AAA_14 PF13173.1 AIN98652.1 - 0.00032 20.6 0.0 0.05 13.5 0.0 2.3 2 0 0 2 2 2 1 AAA domain UPF0079 PF02367.12 AIN98652.1 - 0.00035 20.1 0.1 0.48 10.0 0.1 2.3 2 0 0 2 2 2 2 Uncharacterised P-loop hydrolase UPF0079 Miro PF08477.8 AIN98652.1 - 0.001 19.5 0.0 0.61 10.6 0.0 2.4 2 0 0 2 2 2 1 Miro-like protein Mg_chelatase PF01078.16 AIN98652.1 - 0.0011 18.1 0.0 0.14 11.3 0.0 2.6 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.21 AIN98652.1 - 0.0032 16.9 0.0 0.12 11.8 0.0 2.3 2 0 0 2 2 2 1 Sigma-54 interaction domain NB-ARC PF00931.17 AIN98652.1 - 0.0037 16.1 0.0 0.84 8.4 0.0 2.5 3 0 0 3 3 3 1 NB-ARC domain AAA_30 PF13604.1 AIN98652.1 - 0.004 16.7 0.0 0.14 11.6 0.0 2.4 2 0 0 2 2 2 1 AAA domain TIP49 PF06068.8 AIN98652.1 - 0.0042 15.8 0.0 0.0076 15.0 0.0 1.3 1 0 0 1 1 1 1 TIP49 C-terminus AAA_18 PF13238.1 AIN98652.1 - 0.0057 16.9 0.0 0.13 12.5 0.0 2.2 2 0 0 2 2 2 1 AAA domain Sigma54_activ_2 PF14532.1 AIN98652.1 - 0.0062 16.5 0.1 0.86 9.6 0.0 3.1 3 0 0 3 3 3 1 Sigma-54 interaction domain Viral_helicase1 PF01443.13 AIN98652.1 - 0.0073 15.8 0.0 1.3 8.4 0.0 2.6 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase IstB_IS21 PF01695.12 AIN98652.1 - 0.0083 15.5 0.0 0.14 11.5 0.0 2.6 3 0 0 3 3 3 1 IstB-like ATP binding protein FtsK_SpoIIIE PF01580.13 AIN98652.1 - 0.014 14.8 0.6 0.13 11.7 0.0 2.2 2 0 0 2 2 2 0 FtsK/SpoIIIE family Rad17 PF03215.10 AIN98652.1 - 0.015 13.9 0.3 0.24 10.0 0.1 2.1 2 0 0 2 2 2 0 Rad17 cell cycle checkpoint protein AAA_PrkA PF08298.6 AIN98652.1 - 0.016 13.9 0.0 0.074 11.7 0.0 1.8 2 0 0 2 2 2 0 PrkA AAA domain PRK PF00485.13 AIN98652.1 - 0.017 14.7 0.1 1 8.9 0.0 2.3 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family AAA_23 PF13476.1 AIN98652.1 - 0.019 15.2 0.1 2.5 8.4 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.1 AIN98652.1 - 0.042 13.6 0.1 3.4 7.4 0.0 2.9 3 0 0 3 3 2 0 Part of AAA domain AAA_24 PF13479.1 AIN98652.1 - 0.044 13.3 0.3 3.4 7.2 0.0 2.5 2 1 0 2 2 2 0 AAA domain MobB PF03205.9 AIN98652.1 - 0.068 12.8 0.0 4.8 6.8 0.1 2.3 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B TrwB_AAD_bind PF10412.4 AIN98652.1 - 0.14 10.7 0.1 1.7 7.1 0.0 2.3 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain Hpr_kinase_C PF07475.7 AIN98652.1 - 0.17 11.1 0.3 0.57 9.4 0.0 1.8 2 0 0 2 2 2 0 HPr Serine kinase C-terminal domain Guanylate_kin PF00625.16 AIN98652.1 - 0.21 11.0 0.1 2.9 7.3 0.0 2.5 2 1 1 3 3 3 0 Guanylate kinase AAA_10 PF12846.2 AIN98652.1 - 0.22 10.9 2.0 8.6 5.6 0.0 2.4 2 0 0 2 2 2 0 AAA-like domain G-alpha PF00503.15 AIN98652.1 - 0.44 9.1 0.4 18 3.8 0.0 2.1 2 0 0 2 2 2 0 G-protein alpha subunit HEAT PF02985.17 AIN98653.1 - 1.6e-12 46.3 17.8 0.14 12.2 0.1 7.7 7 0 0 7 7 7 6 HEAT repeat HEAT_2 PF13646.1 AIN98653.1 - 4.8e-11 42.7 13.0 0.0021 18.2 0.0 4.9 4 1 0 4 4 4 3 HEAT repeats Vac14_Fab1_bd PF12755.2 AIN98653.1 - 8e-05 22.9 0.6 2.7 8.4 0.0 4.4 4 0 0 4 4 4 2 Vacuolar 14 Fab1-binding region Adaptin_N PF01602.15 AIN98653.1 - 0.0019 16.5 1.0 0.21 9.8 0.0 3.4 3 2 0 3 3 3 1 Adaptin N terminal region SMN PF06003.7 AIN98653.1 - 0.064 12.3 0.4 0.11 11.6 0.3 1.2 1 0 0 1 1 1 0 Survival motor neuron protein (SMN) TFIIS_M PF07500.9 AIN98655.1 - 2.8e-18 66.0 1.3 4.1e-18 65.5 0.9 1.3 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS), central domain TFIIS_C PF01096.13 AIN98655.1 - 2.1e-14 52.8 4.1 3.6e-14 52.0 2.8 1.4 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS) Baculo_LEF5_C PF11792.3 AIN98655.1 - 0.00014 21.2 0.7 0.00032 20.0 0.5 1.7 1 1 0 1 1 1 1 Baculoviridae late expression factor 5 C-terminal domain Elf1 PF05129.8 AIN98655.1 - 0.045 13.4 1.3 0.086 12.5 0.9 1.4 1 0 0 1 1 1 0 Transcription elongation factor Elf1 like Terminase_2 PF03592.11 AIN98655.1 - 0.3 11.3 1.9 0.45 10.7 0.5 1.8 1 1 1 2 2 2 0 Terminase small subunit Pkinase PF00069.20 AIN98656.1 - 2.3e-52 177.7 0.0 6.3e-52 176.2 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AIN98656.1 - 5.8e-27 94.3 0.0 6.6e-20 71.2 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase FHA PF00498.21 AIN98656.1 - 8.4e-15 54.6 0.1 2.4e-14 53.1 0.1 1.8 1 0 0 1 1 1 1 FHA domain APH PF01636.18 AIN98656.1 - 0.00069 19.4 0.2 0.39 10.3 0.0 2.9 2 1 1 3 3 3 2 Phosphotransferase enzyme family Kinase-like PF14531.1 AIN98656.1 - 0.039 12.9 0.0 0.13 11.1 0.0 1.8 2 0 0 2 2 2 0 Kinase-like RIO1 PF01163.17 AIN98656.1 - 0.073 12.4 0.0 0.11 11.8 0.0 1.2 1 0 0 1 1 1 0 RIO1 family CAF1C_H4-bd PF12265.3 AIN98657.1 - 3.7e-15 55.5 0.2 7.4e-15 54.6 0.1 1.5 1 0 0 1 1 1 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex WD40 PF00400.27 AIN98657.1 - 6e-10 38.6 10.9 4.3e-05 23.2 0.3 4.9 5 0 0 5 5 5 3 WD domain, G-beta repeat DEAD PF00270.24 AIN98658.1 - 3e-32 111.4 0.4 8.8e-32 109.9 0.2 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 AIN98658.1 - 1.7e-14 53.3 0.1 1.5e-08 34.3 0.1 2.7 2 0 0 2 2 2 2 Helicase conserved C-terminal domain ResIII PF04851.10 AIN98658.1 - 4.8e-05 23.2 0.0 0.00029 20.7 0.0 2.2 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit SNF2_N PF00176.18 AIN98658.1 - 0.01 14.6 0.0 0.023 13.5 0.0 1.6 1 0 0 1 1 1 0 SNF2 family N-terminal domain Metallophos PF00149.23 AIN98660.1 - 1.7e-10 40.6 0.1 6.2e-10 38.8 0.0 1.8 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase WD40 PF00400.27 AIN98661.1 - 1.6e-12 46.7 4.3 8.3e-07 28.6 0.1 4.0 3 0 0 3 3 3 2 WD domain, G-beta repeat tify PF06200.9 AIN98661.1 - 0.18 11.1 1.2 1.6 8.0 0.2 2.5 2 0 0 2 2 2 0 tify domain NIF PF03031.13 AIN98662.1 - 6.9e-31 107.0 0.6 1e-30 106.5 0.4 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Hydrolase PF00702.21 AIN98662.1 - 0.18 12.2 0.7 2.5 8.4 0.0 2.8 2 2 1 3 3 3 0 haloacid dehalogenase-like hydrolase zf-C3HC4 PF00097.20 AIN98663.1 - 0.19 11.4 7.6 0.52 10.0 5.3 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 AIN98663.1 - 0.32 10.6 5.7 0.98 9.1 3.9 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) FANCL_C PF11793.3 AIN98663.1 - 0.47 10.4 9.9 0.071 13.0 3.4 2.2 2 0 0 2 2 2 0 FANCL C-terminal domain RINGv PF12906.2 AIN98663.1 - 0.73 9.9 7.2 2.1 8.4 5.0 1.9 1 0 0 1 1 1 0 RING-variant domain Fumerase PF05681.9 AIN98665.1 - 3.5e-86 288.6 0.0 4.4e-86 288.3 0.0 1.1 1 0 0 1 1 1 1 Fumarate hydratase (Fumerase) Fumerase_C PF05683.7 AIN98665.1 - 3.8e-78 261.3 0.0 1.1e-77 259.7 0.0 1.7 2 0 0 2 2 2 1 Fumarase C-terminus Rsm22 PF09243.5 AIN98666.1 - 8.7e-29 100.4 5.8 1.2e-17 63.9 0.1 3.1 4 0 0 4 4 4 2 Mitochondrial small ribosomal subunit Rsm22 Methyltransf_18 PF12847.2 AIN98666.1 - 0.015 15.8 0.5 6.2 7.4 0.0 2.9 2 1 0 2 2 2 0 Methyltransferase domain Phosphodiest PF01663.17 AIN98667.1 - 4.5e-09 36.1 0.0 4.5e-09 36.1 0.0 1.8 3 0 0 3 3 3 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF1845 PF08900.6 AIN98667.1 - 0.059 12.6 0.0 0.1 11.8 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1845) Sulfatase PF00884.18 AIN98667.1 - 0.071 12.2 0.0 0.13 11.4 0.0 1.3 1 0 0 1 1 1 0 Sulfatase Aminotran_1_2 PF00155.16 AIN98669.1 - 6.1e-71 239.2 0.0 6.8e-71 239.1 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II DUF512 PF04459.7 AIN98669.1 - 0.074 12.1 0.0 1.2 8.1 0.0 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF512) TPR_11 PF13414.1 AIN98672.1 - 7.3e-06 25.5 0.9 3e-05 23.5 0.2 2.4 2 1 0 2 2 2 1 TPR repeat TPR_2 PF07719.12 AIN98672.1 - 0.0034 17.1 0.1 1.4 9.0 0.0 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat NAD_binding_9 PF13454.1 AIN98672.1 - 0.0065 16.2 0.6 0.079 12.7 0.1 2.2 2 0 0 2 2 2 1 FAD-NAD(P)-binding Peptidase_C12 PF01088.16 AIN98674.1 - 4.5e-61 205.7 0.0 6.1e-61 205.3 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 RPAP2_Rtr1 PF04181.8 AIN98675.1 - 0.0043 17.1 0.0 0.013 15.6 0.0 1.8 1 0 0 1 1 1 1 Rtr1/RPAP2 family Nuc_sug_transp PF04142.10 AIN98676.1 - 1.1e-49 168.7 14.7 1.8e-49 168.0 10.2 1.3 1 0 0 1 1 1 1 Nucleotide-sugar transporter EmrE PF13536.1 AIN98676.1 - 0.00092 19.3 7.4 0.00092 19.3 5.1 3.0 2 1 1 3 3 3 1 Multidrug resistance efflux transporter OAD_gamma PF04277.8 AIN98676.1 - 0.65 10.4 9.8 40 4.6 0.0 4.4 3 1 0 3 3 3 0 Oxaloacetate decarboxylase, gamma chain EamA PF00892.15 AIN98676.1 - 4.1 7.4 30.1 0.051 13.6 3.6 3.4 2 1 1 3 3 3 0 EamA-like transporter family DUF3184 PF11380.3 AIN98677.1 - 3e-95 319.6 23.3 4.6e-55 186.8 5.4 4.9 2 2 1 3 3 3 3 Protein of unknown function (DUF3184) OEP PF02321.13 AIN98678.1 - 0.1 12.1 0.0 4.1 6.9 0.0 2.1 2 0 0 2 2 2 0 Outer membrane efflux protein ACC_epsilon PF13822.1 AIN98678.1 - 2 8.8 9.0 2 8.8 1.2 3.1 3 0 0 3 3 3 0 Acyl-CoA carboxylase epsilon subunit Kelch_4 PF13418.1 AIN98679.1 - 1.8e-27 94.8 13.2 3.3e-07 29.9 0.0 7.4 6 2 1 7 7 7 4 Galactose oxidase, central domain Kelch_5 PF13854.1 AIN98679.1 - 1e-20 73.2 4.3 1.7e-07 30.9 0.0 6.3 7 0 0 7 7 7 4 Kelch motif Kelch_3 PF13415.1 AIN98679.1 - 2.9e-15 55.9 17.7 2.8e-06 27.3 0.1 10.4 11 0 0 11 11 11 3 Galactose oxidase, central domain Kelch_6 PF13964.1 AIN98679.1 - 7.8e-14 51.1 9.2 0.0055 16.8 0.0 7.6 7 1 2 9 9 9 4 Kelch motif Kelch_2 PF07646.10 AIN98679.1 - 3.3e-08 32.9 0.2 0.065 13.0 0.0 5.3 5 0 0 5 5 5 2 Kelch motif Kelch_1 PF01344.20 AIN98679.1 - 1.1e-06 28.0 0.5 0.002 17.6 0.0 4.7 5 0 0 5 5 5 1 Kelch motif RAG2 PF03089.9 AIN98679.1 - 0.019 13.7 0.0 0.22 10.1 0.0 2.4 2 0 0 2 2 2 0 Recombination activating protein 2 LRR_4 PF12799.2 AIN98680.1 - 5.2e-53 175.9 62.8 4.1e-08 32.6 0.8 14.0 9 3 1 12 12 12 11 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 AIN98680.1 - 1.3e-38 130.5 60.1 4.9e-07 29.4 2.3 9.6 6 3 5 11 11 11 10 Leucine rich repeat LRR_9 PF14580.1 AIN98680.1 - 2.7e-20 72.6 11.0 0.00027 20.5 0.0 7.4 4 3 3 7 7 7 5 Leucine-rich repeat LRR_1 PF00560.28 AIN98680.1 - 6e-14 49.9 67.6 2.9 8.2 0.1 19.5 19 2 2 21 21 21 9 Leucine Rich Repeat LRR_7 PF13504.1 AIN98680.1 - 8.6e-08 31.1 63.5 6.6 7.4 0.0 18.7 20 1 1 21 21 21 6 Leucine rich repeat LRR_6 PF13516.1 AIN98680.1 - 1.2e-07 31.0 40.3 11 6.4 0.0 16.3 15 3 3 18 18 18 1 Leucine Rich repeat DUF1664 PF07889.7 AIN98682.1 - 0.00089 19.0 2.3 0.00089 19.0 1.6 2.8 2 1 0 2 2 2 1 Protein of unknown function (DUF1664) Pro-rich_19 PF15455.1 AIN98682.1 - 0.56 9.1 9.3 1.9 7.4 6.4 1.9 1 0 0 1 1 1 0 Proline-rich 19 DUF788 PF05620.6 AIN98683.1 - 0.065 13.0 0.0 0.14 11.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF788) DnaJ PF00226.26 AIN98683.1 - 0.12 12.1 0.1 0.25 11.0 0.0 1.6 1 0 0 1 1 1 0 DnaJ domain TRM13 PF05206.9 AIN98686.1 - 1.8e-06 27.4 0.0 5.9e-06 25.7 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase TRM13 TRM13 PF05206.9 AIN98687.1 - 3.8e-20 72.2 0.0 7e-20 71.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase TRM13 Methyltransf_32 PF13679.1 AIN98687.1 - 1.1e-06 28.3 0.0 3e-06 26.9 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Sigma70_r4 PF04545.11 AIN98687.1 - 0.055 12.7 0.8 3.1 7.1 0.0 2.5 2 0 0 2 2 2 0 Sigma-70, region 4 MAS20 PF02064.10 AIN98688.1 - 0.026 14.4 0.0 0.034 14.0 0.0 1.2 1 0 0 1 1 1 0 MAS20 protein import receptor WBP-1 PF11669.3 AIN98688.1 - 0.026 14.5 2.6 0.051 13.6 1.8 1.5 1 1 0 1 1 1 0 WW domain-binding protein 1 DUF1049 PF06305.6 AIN98688.1 - 0.04 13.4 0.1 0.061 12.7 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1049) DUF997 PF06196.7 AIN98688.1 - 0.096 12.2 1.4 0.15 11.6 1.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF997) DUF2970 PF11174.3 AIN98688.1 - 0.1 12.1 0.9 0.15 11.6 0.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2970) PepSY_TM_3 PF13706.1 AIN98688.1 - 0.96 8.9 4.0 1.5 8.2 2.8 1.3 1 0 0 1 1 1 0 PepSY-associated TM helix CD34_antigen PF06365.7 AIN98689.1 - 0.066 12.8 0.1 0.077 12.6 0.1 1.1 1 0 0 1 1 1 0 CD34/Podocalyxin family EphA2_TM PF14575.1 AIN98689.1 - 0.082 13.3 0.1 0.1 12.9 0.1 1.1 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Npa1 PF11707.3 AIN98692.1 - 1e-05 24.7 0.0 2.6e-05 23.3 0.0 1.6 1 0 0 1 1 1 1 Ribosome 60S biogenesis N-terminal SNF2_N PF00176.18 AIN98693.1 - 4.6e-37 127.4 0.0 6.7e-37 126.8 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 AIN98693.1 - 1.3e-09 37.7 0.0 6.6e-09 35.5 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.24 AIN98693.1 - 1e-07 31.6 0.0 4.1e-07 29.6 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.10 AIN98693.1 - 4e-05 23.5 0.0 0.00056 19.7 0.0 2.2 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit UCH PF00443.24 AIN98694.1 - 9.5e-46 156.0 0.0 1.4e-45 155.5 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 AIN98694.1 - 1.4e-13 50.9 0.2 1.5e-12 47.5 0.1 2.1 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Kinesin PF00225.18 AIN98695.1 - 1.2e-91 306.9 0.0 1.5e-91 306.5 0.0 1.1 1 0 0 1 1 1 1 Kinesin motor domain Peptidase_C97 PF05903.9 AIN98696.1 - 6.8e-27 94.1 0.0 1.2e-26 93.2 0.0 1.4 1 0 0 1 1 1 1 PPPDE putative peptidase domain LRAT PF04970.8 AIN98696.1 - 0.0054 16.6 0.0 0.013 15.3 0.0 1.6 1 0 0 1 1 1 1 Lecithin retinol acyltransferase HEAT_2 PF13646.1 AIN98697.1 - 0.0061 16.8 3.9 0.84 9.9 0.1 3.7 2 1 0 2 2 2 2 HEAT repeats Pkinase PF00069.20 AIN98698.1 - 2.4e-36 125.2 0.0 4e-36 124.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AIN98698.1 - 3.1e-12 46.1 0.0 2e-11 43.4 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase YrbL-PhoP_reg PF10707.4 AIN98698.1 - 0.21 10.9 0.0 0.34 10.2 0.0 1.2 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Kdo PF06293.9 AIN98698.1 - 0.25 10.3 0.0 0.43 9.6 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Sugar_tr PF00083.19 AIN98699.1 - 9e-118 393.6 38.3 1e-117 393.4 26.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 AIN98699.1 - 4.4e-29 101.3 42.4 4.4e-29 101.3 29.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 AIN98699.1 - 0.00032 19.0 3.4 0.00032 19.0 2.4 1.7 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) DUF523 PF04463.7 AIN98701.1 - 8.9e-14 51.4 0.0 1.3e-06 28.2 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF523) zf-Tim10_DDP PF02953.10 AIN98702.1 - 2.1e-05 23.6 0.7 2.8e-05 23.3 0.5 1.3 1 0 0 1 1 1 1 Tim10/DDP family zinc finger SRP54 PF00448.17 AIN98703.1 - 1.1e-72 243.6 0.6 2.2e-72 242.6 0.4 1.6 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain SRP_SPB PF02978.14 AIN98703.1 - 5.2e-24 84.4 1.8 5.2e-24 84.4 1.3 5.1 3 1 1 5 5 4 1 Signal peptide binding domain SRP54_N PF02881.14 AIN98703.1 - 1.1e-12 47.8 2.2 3e-12 46.4 1.5 1.8 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain cobW PF02492.14 AIN98703.1 - 1.8e-07 30.8 0.1 4.9e-07 29.3 0.1 1.7 1 1 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain AAA_22 PF13401.1 AIN98703.1 - 1.7e-06 28.1 0.7 0.00042 20.4 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.1 AIN98703.1 - 1.9e-06 27.8 0.2 7.5e-06 25.8 0.0 2.0 2 0 0 2 2 2 1 AAA domain CbiA PF01656.18 AIN98703.1 - 1.8e-05 24.2 0.8 5.9e-05 22.5 0.1 2.1 2 1 0 2 2 2 1 CobQ/CobB/MinD/ParA nucleotide binding domain Zeta_toxin PF06414.7 AIN98703.1 - 7.9e-05 21.8 0.0 0.00022 20.4 0.0 1.7 1 0 0 1 1 1 1 Zeta toxin MobB PF03205.9 AIN98703.1 - 0.00012 21.8 0.9 0.0018 18.0 0.1 2.7 2 1 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_16 PF13191.1 AIN98703.1 - 0.00012 22.1 0.6 0.0015 18.5 0.0 2.3 1 1 1 2 2 2 1 AAA ATPase domain AAA_31 PF13614.1 AIN98703.1 - 0.00037 20.4 0.0 1.7 8.5 0.0 3.0 3 0 0 3 3 3 2 AAA domain AAA_30 PF13604.1 AIN98703.1 - 0.0019 17.8 0.8 0.007 15.9 0.2 2.3 2 0 0 2 2 1 1 AAA domain Methyltransf_24 PF13578.1 AIN98703.1 - 0.0025 18.5 0.0 0.0063 17.3 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain ArgK PF03308.11 AIN98703.1 - 0.0027 16.5 0.0 0.011 14.5 0.0 1.9 1 1 0 1 1 1 1 ArgK protein AAA_17 PF13207.1 AIN98703.1 - 0.0063 17.3 0.0 0.016 16.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain APS_kinase PF01583.15 AIN98703.1 - 0.0077 15.9 0.0 0.017 14.8 0.0 1.5 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_25 PF13481.1 AIN98703.1 - 0.0099 15.2 0.0 0.039 13.3 0.0 1.9 1 1 0 1 1 1 1 AAA domain KaiC PF06745.8 AIN98703.1 - 0.024 13.7 0.3 0.34 10.0 0.0 2.5 2 0 0 2 2 2 0 KaiC SRPRB PF09439.5 AIN98703.1 - 0.024 13.8 0.8 2.4 7.3 0.1 2.5 1 1 0 2 2 2 0 Signal recognition particle receptor beta subunit ATP_bind_1 PF03029.12 AIN98703.1 - 0.028 13.9 1.3 0.11 12.0 0.3 2.5 2 1 0 2 2 2 0 Conserved hypothetical ATP binding protein tRNA_NucTransf2 PF09249.6 AIN98703.1 - 0.037 13.8 0.0 7.5 6.4 0.0 2.6 2 0 0 2 2 2 0 tRNA nucleotidyltransferase, second domain AAA PF00004.24 AIN98703.1 - 0.67 10.1 3.9 2.6 8.2 0.2 3.6 3 1 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) Val_tRNA-synt_C PF10458.4 AIN98705.1 - 0.036 14.1 5.8 0.22 11.6 0.1 3.0 3 0 0 3 3 3 0 Valyl tRNA synthetase tRNA binding arm CENP-F_leu_zip PF10473.4 AIN98705.1 - 0.3 10.9 7.2 0.043 13.6 1.7 1.8 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 SNF2_N PF00176.18 AIN98706.1 - 1.1e-61 208.3 0.0 1.6e-61 207.6 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 AIN98706.1 - 1.8e-13 50.1 0.0 4.1e-13 49.0 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 AIN98706.1 - 2.6e-11 43.2 0.0 5.8e-11 42.1 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.10 AIN98706.1 - 0.00038 20.3 0.0 0.00082 19.2 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Malic_M PF03949.10 AIN98707.1 - 9e-76 254.7 0.1 1.3e-75 254.3 0.1 1.2 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.14 AIN98707.1 - 7.7e-67 224.3 0.0 5.1e-66 221.7 0.0 2.0 2 0 0 2 2 2 1 Malic enzyme, N-terminal domain Malic_M PF03949.10 AIN98708.1 - 1.2e-76 257.6 0.0 1.9e-76 257.0 0.0 1.3 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.14 AIN98708.1 - 3e-69 232.2 0.0 4.4e-69 231.7 0.0 1.2 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain PTS_2-RNA PF01885.11 AIN98712.1 - 1.9e-51 174.0 0.0 3.1e-51 173.3 0.0 1.3 1 0 0 1 1 1 1 RNA 2'-phosphotransferase, Tpt1 / KptA family RNase_T PF00929.19 AIN98712.1 - 8.2e-17 61.9 0.0 1.3e-16 61.3 0.0 1.3 1 0 0 1 1 1 1 Exonuclease Dynactin_p62 PF05502.8 AIN98712.1 - 0.072 11.8 0.1 0.11 11.2 0.1 1.3 1 0 0 1 1 1 0 Dynactin p62 family Syja_N PF02383.13 AIN98713.1 - 8.4e-70 235.0 0.0 1.3e-69 234.4 0.0 1.2 1 0 0 1 1 1 1 SacI homology domain Ax_dynein_light PF10211.4 AIN98715.1 - 3.9e-79 264.8 7.3 4.6e-79 264.6 5.1 1.0 1 0 0 1 1 1 1 Axonemal dynein light chain OmpH PF03938.9 AIN98715.1 - 6.3e-05 22.9 4.0 9.1e-05 22.4 2.8 1.2 1 0 0 1 1 1 1 Outer membrane protein (OmpH-like) ERM PF00769.14 AIN98715.1 - 8.6e-05 22.1 9.5 0.00015 21.4 6.6 1.4 1 0 0 1 1 1 1 Ezrin/radixin/moesin family Filament PF00038.16 AIN98715.1 - 0.0002 20.9 9.2 0.00072 19.1 2.2 2.1 1 1 1 2 2 2 2 Intermediate filament protein APG6 PF04111.7 AIN98715.1 - 0.00088 18.4 5.1 0.0014 17.7 3.6 1.3 1 0 0 1 1 1 1 Autophagy protein Apg6 Syntaxin-6_N PF09177.6 AIN98715.1 - 0.0032 17.8 4.5 0.0074 16.6 3.1 1.7 1 0 0 1 1 1 1 Syntaxin 6, N-terminal bZIP_1 PF00170.16 AIN98715.1 - 0.014 15.3 2.2 0.014 15.3 1.5 2.6 3 0 0 3 3 3 0 bZIP transcription factor HALZ PF02183.13 AIN98715.1 - 0.034 13.8 4.6 0.3 10.8 0.7 3.2 3 0 0 3 3 3 0 Homeobox associated leucine zipper Spc24 PF08286.6 AIN98715.1 - 0.038 13.7 4.3 0.071 12.8 3.0 1.5 1 0 0 1 1 1 0 Spc24 subunit of Ndc80 DUF342 PF03961.8 AIN98715.1 - 0.14 10.5 0.8 0.2 10.0 0.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF342) DUF972 PF06156.8 AIN98715.1 - 0.15 12.4 3.9 0.16 12.3 1.7 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF972) CENP-H PF05837.7 AIN98715.1 - 0.19 11.9 4.9 0.35 11.0 3.4 1.5 1 0 0 1 1 1 0 Centromere protein H (CENP-H) TMF_TATA_bd PF12325.3 AIN98715.1 - 0.72 9.5 10.1 0.33 10.6 4.8 1.9 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding Mnd1 PF03962.10 AIN98715.1 - 1.2 8.7 9.6 0.72 9.4 5.5 1.4 2 0 0 2 2 2 0 Mnd1 family DUF1515 PF07439.6 AIN98715.1 - 1.3 8.8 3.4 1.2 9.0 1.2 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1515) Prefoldin PF02996.12 AIN98715.1 - 1.6 8.4 8.3 4.8 6.8 0.3 2.6 2 1 1 3 3 3 0 Prefoldin subunit FlxA PF14282.1 AIN98715.1 - 2.8 7.9 8.1 0.4 10.6 2.7 1.8 2 0 0 2 2 2 0 FlxA-like protein Atg14 PF10186.4 AIN98715.1 - 3.2 6.6 7.6 1.4 7.8 3.7 1.4 2 0 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 TIM PF00121.13 AIN98716.1 - 2.3e-85 285.5 0.5 2.5e-85 285.4 0.3 1.0 1 0 0 1 1 1 1 Triosephosphate isomerase DMRL_synthase PF00885.14 AIN98716.1 - 0.069 12.8 0.4 0.24 11.0 0.0 1.9 2 0 0 2 2 2 0 6,7-dimethyl-8-ribityllumazine synthase EMP24_GP25L PF01105.19 AIN98718.1 - 1.7e-18 66.9 0.0 2.1e-18 66.7 0.0 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD DUF202 PF02656.10 AIN98718.1 - 0.087 13.0 5.6 0.18 12.0 0.3 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF202) DNA_pol_A PF00476.15 AIN98720.1 - 6e-38 130.4 0.0 4.8e-34 117.6 0.0 2.3 2 0 0 2 2 2 2 DNA polymerase family A MCM PF00493.18 AIN98722.1 - 1.6e-118 395.3 0.0 2.3e-118 394.7 0.0 1.2 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 AIN98722.1 - 2.8e-16 60.1 0.0 9.2e-16 58.4 0.0 1.9 2 0 0 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.16 AIN98722.1 - 3.2e-07 29.7 0.0 6.3e-06 25.4 0.0 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.6 AIN98722.1 - 0.00039 20.0 0.0 0.0014 18.2 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 AIN98722.1 - 0.00079 19.1 0.0 0.0017 18.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) PUA PF01472.15 AIN98722.1 - 0.013 15.2 1.2 4.8 6.9 0.1 2.6 2 0 0 2 2 2 0 PUA domain Sigma54_activat PF00158.21 AIN98722.1 - 0.047 13.1 0.0 0.13 11.7 0.0 1.7 1 0 0 1 1 1 0 Sigma-54 interaction domain MTS PF05175.9 AIN98723.1 - 0.00053 19.4 0.0 0.0078 15.6 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_18 PF12847.2 AIN98723.1 - 0.039 14.5 0.0 0.12 12.9 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_26 PF13659.1 AIN98723.1 - 0.094 12.7 0.9 1.4 8.9 0.2 2.7 2 1 0 2 2 2 0 Methyltransferase domain Methyltransf_23 PF13489.1 AIN98723.1 - 0.11 12.2 0.0 0.17 11.5 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain RabGAP-TBC PF00566.13 AIN98726.1 - 7.8e-09 35.3 2.4 2.4e-08 33.7 2.0 1.5 2 0 0 2 2 2 1 Rab-GTPase-TBC domain RFC1 PF08519.7 AIN98730.1 - 3.6e-47 159.9 0.0 7.3e-47 158.9 0.0 1.6 1 0 0 1 1 1 1 Replication factor RFC1 C terminal domain AAA PF00004.24 AIN98730.1 - 3.8e-12 46.5 0.0 1.1e-11 45.1 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.10 AIN98730.1 - 1e-09 37.6 0.0 1.5e-07 30.4 0.0 2.3 2 0 0 2 2 2 1 Rad17 cell cycle checkpoint protein AAA_22 PF13401.1 AIN98730.1 - 8.2e-05 22.7 0.0 0.00024 21.2 0.0 1.8 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 AIN98730.1 - 0.0004 19.5 0.0 0.0012 18.0 0.0 1.7 1 0 0 1 1 1 1 Zeta toxin AAA_14 PF13173.1 AIN98730.1 - 0.00041 20.2 0.0 0.00083 19.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.7 AIN98730.1 - 0.0012 17.9 0.0 0.0024 16.9 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_28 PF13521.1 AIN98730.1 - 0.0016 18.3 0.5 0.13 12.2 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 AIN98730.1 - 0.0023 18.7 0.0 0.0071 17.1 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 AIN98730.1 - 0.0029 17.6 0.0 0.0078 16.2 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.9 AIN98730.1 - 0.0029 17.3 0.0 0.0057 16.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_19 PF13245.1 AIN98730.1 - 0.0083 15.8 1.8 0.013 15.2 0.0 2.2 2 1 0 2 2 2 1 Part of AAA domain AAA_18 PF13238.1 AIN98730.1 - 0.013 15.8 0.0 0.033 14.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.1 AIN98730.1 - 0.02 14.8 0.0 0.062 13.1 0.0 1.8 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 AIN98730.1 - 0.022 14.9 0.0 0.064 13.4 0.0 1.8 1 0 0 1 1 1 0 RNA helicase NTPase_1 PF03266.10 AIN98730.1 - 0.046 13.4 0.3 0.1 12.3 0.0 1.7 2 0 0 2 2 2 0 NTPase DUF755 PF05501.6 AIN98730.1 - 3.8 7.5 28.5 7.3 6.6 17.6 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF755) Mnd1 PF03962.10 AIN98732.1 - 3.6e-28 98.5 0.0 7.5e-28 97.4 0.0 1.5 1 1 0 1 1 1 1 Mnd1 family Kelch_4 PF13418.1 AIN98733.1 - 1.3e-14 53.7 2.7 3.8e-07 29.7 0.0 4.3 4 0 0 4 4 4 2 Galactose oxidase, central domain Kelch_6 PF13964.1 AIN98733.1 - 1.5e-14 53.4 3.9 0.00023 21.1 0.0 4.4 4 0 0 4 4 4 3 Kelch motif Kelch_1 PF01344.20 AIN98733.1 - 1.5e-12 46.8 0.1 3e-05 23.4 0.0 3.3 3 0 0 3 3 3 2 Kelch motif Kelch_5 PF13854.1 AIN98733.1 - 1.5e-09 37.6 0.4 0.0013 18.6 0.0 3.2 3 0 0 3 3 3 2 Kelch motif Kelch_3 PF13415.1 AIN98733.1 - 2.3e-09 37.1 0.4 0.059 13.5 0.1 4.1 3 0 0 3 3 3 3 Galactose oxidase, central domain F-box-like PF12937.2 AIN98733.1 - 1.4e-05 24.6 0.1 2.8e-05 23.7 0.1 1.5 1 0 0 1 1 1 1 F-box-like Kelch_2 PF07646.10 AIN98733.1 - 5.8e-05 22.6 0.0 0.062 13.0 0.0 3.6 3 0 0 3 3 3 1 Kelch motif F-box PF00646.28 AIN98733.1 - 0.00013 21.5 0.0 0.00037 20.0 0.0 1.7 1 0 0 1 1 1 1 F-box domain FAM75 PF14650.1 AIN98733.1 - 0.0075 15.7 0.5 0.015 14.6 0.3 1.5 1 0 0 1 1 1 1 FAM75 family LRR_4 PF12799.2 AIN98734.1 - 1.3e-16 59.8 14.4 7.8e-09 34.9 1.7 3.6 3 1 0 3 3 3 2 Leucine Rich repeats (2 copies) LRR_9 PF14580.1 AIN98734.1 - 1.9e-08 34.0 0.8 1.7e-07 30.9 0.5 2.1 1 1 0 1 1 1 1 Leucine-rich repeat LRR_8 PF13855.1 AIN98734.1 - 9.1e-08 31.7 10.3 3.2e-05 23.6 0.4 3.0 1 1 2 3 3 3 2 Leucine rich repeat LRR_1 PF00560.28 AIN98734.1 - 0.00011 21.7 6.0 3.1 8.1 1.2 4.7 3 2 1 4 4 4 2 Leucine Rich Repeat LRR_7 PF13504.1 AIN98734.1 - 0.00021 20.9 6.4 1.4 9.4 0.2 4.6 4 1 1 5 5 5 2 Leucine rich repeat LRR_6 PF13516.1 AIN98734.1 - 0.00047 19.9 7.7 2.3 8.5 0.3 4.7 4 1 1 5 5 5 2 Leucine Rich repeat FNIP PF05725.7 AIN98734.1 - 0.028 14.3 0.0 0.26 11.2 0.0 2.2 1 1 1 2 2 2 0 FNIP Repeat Rubredoxin PF00301.15 AIN98735.1 - 0.35 10.7 0.1 0.35 10.7 0.0 3.1 3 0 0 3 3 3 0 Rubredoxin SNF2_N PF00176.18 AIN98736.1 - 3.1e-37 127.9 0.0 6.4e-37 126.9 0.0 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 AIN98736.1 - 2.3e-12 46.5 0.0 1e-10 41.3 0.0 2.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 AIN98736.1 - 0.0082 15.9 0.0 0.18 11.6 0.0 3.0 3 1 0 3 3 3 1 Type III restriction enzyme, res subunit AKAP7_NLS PF10469.4 AIN98737.1 - 4.3e-19 69.0 0.0 1.1e-18 67.7 0.0 1.6 1 1 0 1 1 1 1 AKAP7 2'5' RNA ligase-like domain CbbQ_C PF08406.5 AIN98737.1 - 0.073 13.0 0.2 0.18 11.8 0.2 1.6 1 0 0 1 1 1 0 CbbQ/NirQ/NorQ C-terminal zf-ribbon_3 PF13248.1 AIN98737.1 - 1.9 7.7 4.4 0.42 9.8 0.7 1.7 2 0 0 2 2 2 0 zinc-ribbon domain TRAPPC10 PF12584.3 AIN98738.1 - 0.07 12.6 0.0 0.19 11.2 0.0 1.7 1 0 0 1 1 1 0 Trafficking protein particle complex subunit 10, TRAPPC10 DnaJ PF00226.26 AIN98739.1 - 7.5e-15 54.4 0.0 2.6e-14 52.6 0.0 1.9 2 0 0 2 2 2 1 DnaJ domain DUF872 PF05915.7 AIN98740.1 - 8.8 6.2 9.3 9.7 6.0 0.1 4.1 4 0 0 4 4 4 0 Eukaryotic protein of unknown function (DUF872) HA2 PF04408.18 AIN98741.1 - 4.6e-14 52.2 0.0 1.1e-13 51.0 0.0 1.7 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 AIN98741.1 - 1.7e-12 47.1 0.0 4.1e-12 45.9 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.26 AIN98741.1 - 1.9e-11 43.6 0.1 7.1e-11 41.8 0.1 2.0 1 1 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 AIN98741.1 - 2.2e-05 24.0 0.1 5.1e-05 22.8 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 AIN98741.1 - 0.0012 18.9 0.0 0.0035 17.4 0.0 1.8 1 0 0 1 1 1 1 AAA domain KaiC PF06745.8 AIN98741.1 - 0.11 11.5 0.0 0.23 10.5 0.0 1.4 1 0 0 1 1 1 0 KaiC FH2 PF02181.18 AIN98742.1 - 1.2e-53 182.3 0.0 1.5e-53 182.0 0.0 1.1 1 0 0 1 1 1 1 Formin Homology 2 Domain PTEN_C2 PF10409.4 AIN98742.1 - 0.0061 16.2 0.0 0.015 15.0 0.0 1.6 2 0 0 2 2 2 1 C2 domain of PTEN tumour-suppressor protein Erp_C PF06780.6 AIN98745.1 - 8.5 6.2 14.2 1.5 8.6 0.7 3.4 3 0 0 3 3 3 0 Erp protein C-terminus RNA_pol PF00940.14 AIN98747.1 - 4.3e-130 433.8 0.0 6e-130 433.3 0.0 1.2 1 0 0 1 1 1 1 DNA-dependent RNA polymerase BCAS2 PF05700.6 AIN98748.1 - 0.0082 15.6 7.8 0.0082 15.6 5.4 2.7 3 0 0 3 3 3 1 Breast carcinoma amplified sequence 2 (BCAS2) Spc7 PF08317.6 AIN98748.1 - 8.7 4.8 14.1 0.45 9.1 3.2 2.4 3 0 0 3 3 3 0 Spc7 kinetochore protein Adaptin_binding PF10199.4 AIN98749.1 - 0.00021 21.5 0.0 0.068 13.4 0.0 3.1 3 1 0 3 3 3 2 Alpha and gamma adaptin binding protein p34 Med3 PF11593.3 AIN98749.1 - 5.8 6.0 11.9 0.32 10.1 4.1 1.9 2 0 0 2 2 2 0 Mediator complex subunit 3 fungal SURF6 PF04935.7 AIN98750.1 - 5.5e-11 42.1 15.2 1.2e-10 41.0 9.9 1.8 1 1 1 2 2 2 1 Surfeit locus protein 6 DUF429 PF04250.8 AIN98750.1 - 0.093 11.9 4.7 3.1 6.9 0.9 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF429) Bax1-I PF01027.15 AIN98751.1 - 2e-37 128.8 20.4 2e-37 128.8 14.2 1.3 2 0 0 2 2 2 1 Inhibitor of apoptosis-promoting Bax1 YL1 PF05764.8 AIN98752.1 - 5e-08 32.8 20.6 5e-08 32.8 14.2 1.7 1 1 1 2 2 2 1 YL1 nuclear protein SUI1 PF01253.17 AIN98753.1 - 1.3e-23 82.5 0.3 1.8e-23 82.1 0.2 1.2 1 0 0 1 1 1 1 Translation initiation factor SUI1 DUF3694 PF12473.3 AIN98753.1 - 0.11 12.1 0.1 0.13 11.8 0.1 1.1 1 0 0 1 1 1 0 Kinesin protein RRM_6 PF14259.1 AIN98754.1 - 0.034 14.1 0.0 0.074 13.0 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) PHD PF00628.24 AIN98755.1 - 5.5e-07 29.1 7.8 5.5e-07 29.1 5.4 1.8 2 0 0 2 2 2 1 PHD-finger Acetyltransf_7 PF13508.1 AIN98755.1 - 0.088 12.9 0.0 0.19 11.9 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 AIN98755.1 - 0.14 12.1 0.2 0.88 9.6 0.0 2.3 2 1 0 2 2 2 0 Acetyltransferase (GNAT) family Amastin PF07344.6 AIN98757.1 - 1.2e-33 115.8 13.6 1.5e-33 115.6 9.4 1.0 1 0 0 1 1 1 1 Amastin surface glycoprotein WASH-7_mid PF14744.1 AIN98758.1 - 9.4e-138 458.8 1.1 1.5e-137 458.1 0.8 1.3 1 0 0 1 1 1 1 WASH complex subunit 7 WASH-7_C PF14746.1 AIN98758.1 - 1.6e-53 180.7 0.1 1.6e-53 180.7 0.1 1.9 2 0 0 2 2 2 1 WASH complex subunit 7, C-terminal WASH-7_N PF14745.1 AIN98758.1 - 8.1e-46 156.3 0.0 1.8e-22 79.2 0.0 3.1 2 2 0 2 2 2 2 WASH complex subunit 7, N-terminal DnaJ PF00226.26 AIN98759.1 - 4.1e-10 39.2 0.0 1e-09 37.9 0.0 1.6 1 0 0 1 1 1 1 DnaJ domain CCG PF02754.11 AIN98759.1 - 0.021 14.8 0.1 0.081 12.9 0.0 2.0 2 0 0 2 2 2 0 Cysteine-rich domain YjcZ PF13990.1 AIN98759.1 - 0.07 12.2 0.0 0.12 11.4 0.0 1.3 1 0 0 1 1 1 0 YjcZ-like protein BLUF PF04940.7 AIN98760.1 - 0.022 14.4 0.0 0.067 12.9 0.0 1.8 1 0 0 1 1 1 0 Sensors of blue-light using FAD Pro_isomerase PF00160.16 AIN98761.1 - 7.7e-23 81.4 0.0 1e-22 81.0 0.0 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD TRAPP PF04051.11 AIN98762.1 - 1.3e-07 31.2 0.0 1.5e-07 31.0 0.0 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component GTP_EFTU PF00009.22 AIN98764.1 - 3.7e-25 88.4 1.2 4.4e-24 84.9 0.9 2.2 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 AIN98764.1 - 2.2e-09 37.2 0.0 6.5e-09 35.7 0.0 1.9 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 AIN98764.1 - 1.5e-06 28.6 0.0 6.1e-06 26.7 0.0 2.1 1 0 0 1 1 1 1 Miro-like protein PduV-EutP PF10662.4 AIN98764.1 - 1.7e-05 24.3 0.1 0.00015 21.2 0.0 2.4 2 1 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation IF-2 PF11987.3 AIN98764.1 - 0.0036 17.1 0.0 0.0085 15.9 0.0 1.6 1 0 0 1 1 1 1 Translation-initiation factor 2 Dynamin_N PF00350.18 AIN98764.1 - 0.015 15.1 4.8 0.12 12.2 0.0 3.4 3 1 1 4 4 4 0 Dynamin family FeoB_N PF02421.13 AIN98764.1 - 0.021 14.1 0.2 0.086 12.1 0.2 2.0 1 1 0 1 1 1 0 Ferrous iron transport protein B cobW PF02492.14 AIN98764.1 - 0.024 14.0 4.4 0.089 12.2 0.4 3.3 3 1 1 4 4 4 0 CobW/HypB/UreG, nucleotide-binding domain DUF1484 PF07363.6 AIN98764.1 - 0.05 13.9 0.3 0.16 12.3 0.1 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF1484) IQ PF00612.22 AIN98765.1 - 1.3e-07 30.5 40.0 0.02 14.4 0.2 7.1 6 1 0 6 6 6 4 IQ calmodulin-binding motif Hid1 PF12722.2 AIN98766.1 - 7.1e-28 96.8 3.6 2.7e-14 51.9 0.6 3.2 3 0 0 3 3 3 3 High-temperature-induced dauer-formation protein Dymeclin PF09742.4 AIN98766.1 - 3.3e-21 75.0 0.0 4.7e-17 61.3 0.0 2.5 2 1 0 2 2 2 2 Dyggve-Melchior-Clausen syndrome protein Hist_deacetyl PF00850.14 AIN98767.1 - 3.6e-67 226.8 0.2 4.3e-67 226.6 0.2 1.1 1 0 0 1 1 1 1 Histone deacetylase domain EF-hand_7 PF13499.1 AIN98768.1 - 4.6e-20 71.5 6.6 1.4e-11 44.3 0.3 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.27 AIN98768.1 - 8.7e-20 68.4 5.7 8.7e-05 21.5 0.0 4.3 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.1 AIN98768.1 - 6.2e-18 63.0 4.8 0.001 18.7 0.1 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.1 AIN98768.1 - 3.1e-15 54.7 7.6 0.00018 20.7 0.1 4.3 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.1 AIN98768.1 - 1.8e-11 43.4 6.7 3.3e-05 23.4 0.2 3.8 3 1 1 4 4 4 3 EF-hand domain pair zf-C3HC4_3 PF13920.1 AIN98768.1 - 1.9e-11 43.4 6.3 1.9e-11 43.4 4.4 1.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 AIN98768.1 - 3e-09 36.7 9.5 3e-09 36.7 6.6 1.8 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 AIN98768.1 - 1e-08 34.7 7.4 1e-08 34.7 5.1 1.8 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_2 PF13639.1 AIN98768.1 - 2.6e-07 30.3 9.1 5.6e-07 29.2 6.3 1.6 1 0 0 1 1 1 1 Ring finger domain SPARC_Ca_bdg PF10591.4 AIN98768.1 - 4.4e-07 29.9 0.0 0.00019 21.4 0.0 2.5 2 0 0 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region zf-C3HC4 PF00097.20 AIN98768.1 - 2.4e-06 27.0 9.1 2.4e-06 27.0 6.3 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.1 AIN98768.1 - 3.7e-05 23.4 4.1 7.7e-05 22.4 2.8 1.5 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-RING_UBOX PF13445.1 AIN98768.1 - 7.5e-05 22.3 4.7 0.00057 19.5 3.3 2.3 1 1 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_4 PF15227.1 AIN98768.1 - 0.00025 20.8 4.8 0.00025 20.8 3.4 2.5 1 1 1 2 2 2 1 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.1 AIN98768.1 - 0.021 14.3 5.7 0.057 12.9 4.0 1.7 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 EF-hand_10 PF14788.1 AIN98768.1 - 0.037 13.7 0.2 27 4.5 0.0 3.5 3 1 1 4 4 4 0 EF hand Rtf2 PF04641.7 AIN98768.1 - 0.19 10.8 1.6 0.26 10.4 1.1 1.1 1 0 0 1 1 1 0 Rtf2 RING-finger TMF_TATA_bd PF12325.3 AIN98769.1 - 0.02 14.6 16.4 0.14 11.8 9.5 2.3 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding DUF4200 PF13863.1 AIN98769.1 - 0.45 10.4 25.3 1.6 8.6 11.2 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) IncA PF04156.9 AIN98769.1 - 0.72 9.4 18.5 2 7.9 12.8 1.7 1 1 0 1 1 1 0 IncA protein V_ATPase_I PF01496.14 AIN98769.1 - 0.88 7.3 6.6 1 7.1 4.6 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Atg14 PF10186.4 AIN98769.1 - 1.4 7.8 12.6 1.8 7.4 8.7 1.3 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DUF641 PF04859.7 AIN98769.1 - 1.4 8.6 16.0 0.34 10.6 5.1 2.8 1 1 2 3 3 3 0 Plant protein of unknown function (DUF641) CENP-H PF05837.7 AIN98769.1 - 1.9 8.7 14.1 2.1 8.5 4.9 2.4 1 1 1 2 2 2 0 Centromere protein H (CENP-H) Borrelia_P83 PF05262.6 AIN98769.1 - 3.2 5.9 13.9 4 5.6 9.6 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein DUF4407 PF14362.1 AIN98769.1 - 6.2 5.6 14.6 8.4 5.2 10.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF16 PF01519.11 AIN98769.1 - 6.8 6.9 8.0 17 5.7 3.6 2.2 1 1 1 2 2 2 0 Protein of unknown function DUF16 SlyX PF04102.7 AIN98769.1 - 7.3 7.0 13.6 11 6.4 0.1 3.5 1 1 2 3 3 3 0 SlyX ADIP PF11559.3 AIN98769.1 - 8 6.3 23.5 2 8.2 9.9 2.4 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding DNA_mis_repair PF01119.14 AIN98771.1 - 1.3e-23 82.7 0.0 2.3e-23 81.9 0.0 1.4 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.1 AIN98771.1 - 6e-10 38.9 0.0 1.9e-09 37.2 0.0 1.8 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 AIN98771.1 - 1.1e-08 34.7 0.0 2.5e-08 33.6 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Kinesin PF00225.18 AIN98772.1 - 1.2e-55 188.5 0.0 2e-54 184.5 0.0 2.2 1 1 0 1 1 1 1 Kinesin motor domain P4Ha_N PF08336.6 AIN98772.1 - 1.2 8.9 2.0 2.6 7.8 1.4 1.5 1 0 0 1 1 1 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region HpcH_HpaI PF03328.9 AIN98774.1 - 2.9e-18 65.5 0.0 9.4e-08 31.2 0.0 2.9 2 1 0 2 2 2 2 HpcH/HpaI aldolase/citrate lyase family C-C_Bond_Lyase PF15617.1 AIN98774.1 - 1.3e-13 50.5 0.0 3.8e-07 29.2 0.1 2.1 2 0 0 2 2 2 2 C-C_Bond_Lyase of the TIM-Barrel fold Pkinase PF00069.20 AIN98775.1 - 3.1e-64 216.6 0.0 4.1e-64 216.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AIN98775.1 - 5.1e-41 140.4 0.0 6.9e-41 140.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 AIN98775.1 - 0.0002 20.4 0.0 0.0014 17.6 0.0 2.1 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 AIN98775.1 - 0.018 14.7 0.0 0.41 10.3 0.1 2.8 1 1 2 3 3 3 0 Phosphotransferase enzyme family WD40 PF00400.27 AIN98777.1 - 2.8e-05 23.8 0.2 0.21 11.5 0.0 5.8 6 0 0 6 6 6 1 WD domain, G-beta repeat DUF2921 PF11145.3 AIN98778.1 - 0.012 13.3 0.0 0.018 12.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2921) START PF01852.14 AIN98778.1 - 0.025 13.8 0.0 2 7.6 0.0 2.9 3 0 0 3 3 3 0 START domain WD40 PF00400.27 AIN98779.1 - 1.7e-15 56.2 7.5 2.4e-08 33.5 0.5 5.0 5 0 0 5 5 5 4 WD domain, G-beta repeat TCTP PF00838.12 AIN98780.1 - 2.6e-38 131.6 1.4 3e-38 131.4 0.9 1.0 1 0 0 1 1 1 1 Translationally controlled tumour protein AAA_15 PF13175.1 AIN98780.1 - 0.02 13.9 0.1 0.024 13.7 0.1 1.1 1 0 0 1 1 1 0 AAA ATPase domain RICH PF05062.7 AIN98780.1 - 0.057 13.5 0.4 0.11 12.6 0.3 1.4 1 0 0 1 1 1 0 RICH domain Ribosomal_S20p PF01649.13 AIN98780.1 - 0.064 13.6 0.5 0.11 12.8 0.3 1.4 1 0 0 1 1 1 0 Ribosomal protein S20 AlaDh_PNT_C PF01262.16 AIN98780.1 - 0.07 12.6 0.2 0.11 12.0 0.1 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain ERCC4 PF02732.10 AIN98781.1 - 2.4e-10 40.3 0.0 4.9e-10 39.3 0.0 1.6 1 0 0 1 1 1 1 ERCC4 domain SAP PF02037.22 AIN98781.1 - 1.6e-05 24.3 0.1 5.1e-05 22.6 0.1 1.9 1 0 0 1 1 1 1 SAP domain Helicase_C PF00271.26 AIN98782.1 - 1.4e-15 56.8 0.0 1.8e-14 53.3 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.24 AIN98782.1 - 2.5e-15 56.3 0.0 1.5e-14 53.8 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase HRDC PF00570.18 AIN98782.1 - 6.9e-05 22.4 0.0 0.00015 21.4 0.0 1.5 1 0 0 1 1 1 1 HRDC domain Choline_kin_N PF04428.9 AIN98782.1 - 0.094 12.1 0.0 0.22 10.9 0.0 1.6 1 0 0 1 1 1 0 Choline kinase N terminus Clat_adaptor_s PF01217.15 AIN98783.1 - 1.1e-44 151.5 0.8 1.3e-44 151.3 0.6 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain LRR_6 PF13516.1 AIN98785.1 - 0.017 15.1 0.2 22 5.5 0.0 3.7 3 0 0 3 3 3 0 Leucine Rich repeat EF-hand_1 PF00036.27 AIN98785.1 - 0.036 13.3 0.5 15 5.1 0.0 3.1 3 0 0 3 3 3 0 EF hand EF-hand_6 PF13405.1 AIN98785.1 - 0.05 13.5 0.0 13 6.0 0.0 2.9 2 0 0 2 2 2 0 EF-hand domain LRR_8 PF13855.1 AIN98785.1 - 0.16 11.7 0.2 0.35 10.6 0.1 1.6 1 0 0 1 1 1 0 Leucine rich repeat RRM_1 PF00076.17 AIN98786.1 - 1.3e-33 114.4 1.4 8.9e-22 76.5 0.0 3.4 2 1 1 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 AIN98786.1 - 6.1e-26 90.1 0.3 8.4e-16 57.7 0.0 3.2 2 1 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 AIN98786.1 - 1.4e-18 66.4 0.0 5.8e-12 45.2 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 AIN98786.1 - 6.8e-05 22.5 0.0 0.056 13.2 0.0 2.5 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif Limkain-b1 PF11608.3 AIN98786.1 - 0.011 15.5 0.0 0.024 14.4 0.0 1.6 1 0 0 1 1 1 0 Limkain b1 UBA PF00627.26 AIN98787.1 - 0.0014 18.3 0.2 0.0034 17.1 0.1 1.6 1 0 0 1 1 1 1 UBA/TS-N domain UBA_4 PF14555.1 AIN98787.1 - 0.12 11.9 0.0 0.28 10.7 0.0 1.6 1 0 0 1 1 1 0 UBA-like domain Rhomboid PF01694.17 AIN98787.1 - 0.13 12.2 2.5 0.11 12.4 0.5 1.8 2 1 0 2 2 2 0 Rhomboid family DUF1771 PF08590.5 AIN98789.1 - 0.059 13.3 3.8 0.13 12.2 2.6 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF1771) HpaP PF09483.5 AIN98789.1 - 0.19 11.6 4.1 0.21 11.5 2.8 1.1 1 0 0 1 1 1 0 Type III secretion protein (HpaP) DUF3359 PF11839.3 AIN98789.1 - 2.7 8.3 10.2 0.62 10.4 1.7 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3359) zf-rbx1 PF12678.2 AIN98790.1 - 2.6e-22 78.7 8.8 3.5e-22 78.2 6.1 1.2 1 0 0 1 1 1 1 RING-H2 zinc finger zf-Apc11 PF12861.2 AIN98790.1 - 4.3e-12 45.7 10.0 5.8e-12 45.2 6.5 1.5 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_2 PF13639.1 AIN98790.1 - 1e-07 31.6 15.5 1.9e-06 27.5 10.7 2.1 1 1 1 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.20 AIN98790.1 - 2.8e-06 26.8 11.0 4.3e-05 23.0 7.6 2.2 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 AIN98790.1 - 1.2e-05 24.8 3.6 1.2e-05 24.8 2.5 2.1 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 AIN98790.1 - 3.7e-05 23.6 13.3 0.0001 22.2 5.2 2.3 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-HC5HC2H_2 PF13832.1 AIN98790.1 - 0.005 16.8 4.4 0.0068 16.3 3.1 1.3 1 0 0 1 1 1 1 PHD-zinc-finger like domain FANCL_C PF11793.3 AIN98790.1 - 0.047 13.6 9.9 0.094 12.6 6.9 1.5 1 1 0 1 1 1 0 FANCL C-terminal domain zf-RING_5 PF14634.1 AIN98790.1 - 0.1 12.3 13.8 1.1 9.0 9.6 2.1 1 1 0 1 1 1 0 zinc-RING finger domain Baculo_RING PF05883.6 AIN98790.1 - 0.34 10.7 5.6 1 9.2 3.9 1.7 1 1 0 1 1 1 0 Baculovirus U-box/Ring-like domain zf-RING_UBOX PF13445.1 AIN98790.1 - 0.68 9.6 7.2 2 8.1 5.0 2.0 1 1 0 1 1 1 0 RING-type zinc-finger zf-HC5HC2H PF13771.1 AIN98790.1 - 2.1 8.5 10.8 12 6.1 7.2 2.0 1 1 0 1 1 1 0 PHD-like zinc-binding domain GST_C_2 PF13410.1 AIN98791.1 - 9.5e-05 22.2 0.0 0.00023 20.9 0.0 1.8 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 AIN98791.1 - 0.011 16.2 0.0 0.024 15.0 0.0 1.7 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain FAD_binding_2 PF00890.19 AIN98792.1 - 2.1e-117 392.4 3.1 2.2e-116 389.1 1.1 2.0 2 0 0 2 2 2 1 FAD binding domain Succ_DH_flav_C PF02910.15 AIN98792.1 - 4.2e-44 149.5 0.8 6.1e-44 148.9 0.5 1.3 1 0 0 1 1 1 1 Fumarate reductase flavoprotein C-term DAO PF01266.19 AIN98792.1 - 2.9e-05 23.1 0.2 0.02 13.7 0.1 2.5 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 AIN98792.1 - 7.6e-05 22.6 0.1 0.01 15.7 0.1 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 AIN98792.1 - 9.6e-05 21.5 0.4 0.037 13.1 0.1 2.6 2 0 0 2 2 2 2 Thi4 family HI0933_like PF03486.9 AIN98792.1 - 0.016 13.6 0.1 0.028 12.9 0.1 1.3 1 0 0 1 1 1 0 HI0933-like protein GIDA PF01134.17 AIN98792.1 - 0.041 12.7 3.3 0.092 11.5 1.7 1.8 2 0 0 2 2 2 0 Glucose inhibited division protein A Lycopene_cycl PF05834.7 AIN98792.1 - 0.25 10.2 1.6 1 8.2 0.4 2.0 2 0 0 2 2 2 0 Lycopene cyclase protein FAD_binding_3 PF01494.14 AIN98792.1 - 0.34 9.9 2.8 0.97 8.4 0.2 2.2 2 0 0 2 2 2 0 FAD binding domain NAD_binding_4 PF07993.7 AIN98793.1 - 3.9e-63 212.6 0.0 5.5e-63 212.1 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.16 AIN98793.1 - 8.1e-09 35.2 0.0 3.9e-08 33.0 0.0 2.1 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Sterile PF03015.14 AIN98793.1 - 2.4e-08 34.1 0.0 4.8e-08 33.1 0.0 1.6 1 0 0 1 1 1 1 Male sterility protein RmlD_sub_bind PF04321.12 AIN98793.1 - 5.7e-05 22.1 0.0 0.03 13.2 0.0 2.9 3 0 0 3 3 3 2 RmlD substrate binding domain 3Beta_HSD PF01073.14 AIN98793.1 - 0.0018 17.0 0.1 0.27 9.8 0.1 3.0 2 1 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Semialdhyde_dh PF01118.19 AIN98793.1 - 0.0093 16.2 0.0 0.02 15.2 0.0 1.5 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Polysacc_synt_2 PF02719.10 AIN98793.1 - 0.032 13.1 0.3 1 8.1 0.2 2.3 1 1 0 1 1 1 0 Polysaccharide biosynthesis protein DUF4515 PF14988.1 AIN98794.1 - 0.43 10.2 47.0 0.61 9.7 4.0 3.3 1 1 2 4 4 4 0 Domain of unknown function (DUF4515) Filament PF00038.16 AIN98794.1 - 1.5 8.2 46.4 0.25 10.7 0.5 3.1 1 1 2 3 3 3 0 Intermediate filament protein TMF_TATA_bd PF12325.3 AIN98794.1 - 1.6 8.4 39.4 0.039 13.6 7.7 4.3 2 2 1 3 3 3 0 TATA element modulatory factor 1 TATA binding HR1 PF02185.11 AIN98794.1 - 2.8 7.7 21.4 0.84 9.4 0.3 4.2 3 1 0 3 3 3 0 Hr1 repeat SpoU_methylase PF00588.14 AIN98795.1 - 1.2e-14 54.4 0.0 2.7e-12 46.7 0.0 2.6 1 1 0 1 1 1 1 SpoU rRNA Methylase family Pterin_4a PF01329.14 AIN98796.1 - 0.097 12.4 0.0 0.34 10.6 0.0 1.9 1 1 0 1 1 1 0 Pterin 4 alpha carbinolamine dehydratase BRF1 PF07741.8 AIN98796.1 - 2.6 8.3 8.4 4.2 7.6 3.3 2.6 1 1 2 3 3 3 0 Brf1-like TBP-binding domain Ssl1 PF04056.9 AIN98797.1 - 9.4e-18 64.4 0.1 2.8e-08 33.6 0.0 2.2 1 1 0 2 2 2 2 Ssl1-like VWA_2 PF13519.1 AIN98797.1 - 0.00099 19.2 0.0 0.0015 18.7 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain C1_4 PF07975.7 AIN98797.1 - 0.036 14.0 0.7 0.036 14.0 0.5 3.3 5 0 0 5 5 5 0 TFIIH C1-like domain SET PF00856.23 AIN98798.1 - 7.2e-10 39.3 0.0 1.7e-08 34.9 0.0 2.2 1 1 0 1 1 1 1 SET domain TPR_1 PF00515.23 AIN98798.1 - 0.001 18.6 0.8 0.001 18.6 0.6 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.1 AIN98798.1 - 0.021 14.4 0.6 0.08 12.6 0.0 2.1 2 0 0 2 2 2 0 TPR repeat TPR_2 PF07719.12 AIN98798.1 - 0.026 14.4 3.4 0.037 13.9 0.3 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat UQ_con PF00179.21 AIN98800.1 - 6.8e-18 64.4 0.0 8.9e-18 64.0 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 AIN98800.1 - 0.092 12.5 0.0 0.14 11.9 0.0 1.5 1 1 0 1 1 1 0 Prokaryotic E2 family B WD40 PF00400.27 AIN98801.1 - 2.7e-32 109.4 10.3 4.6e-08 32.6 0.0 6.9 6 0 0 6 6 6 6 WD domain, G-beta repeat eIF2A PF08662.6 AIN98801.1 - 8.9e-08 32.0 0.0 0.051 13.2 0.0 3.1 2 1 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A IKI3 PF04762.7 AIN98801.1 - 0.07 10.9 1.2 0.64 7.7 0.0 2.5 2 1 0 2 2 2 0 IKI3 family Pkinase PF00069.20 AIN98802.1 - 8.1e-49 166.1 0.0 1.2e-48 165.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AIN98802.1 - 6.2e-27 94.2 0.0 1.4e-26 93.1 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 AIN98802.1 - 9.2e-06 24.8 0.1 0.00023 20.2 0.0 2.2 2 0 0 2 2 2 1 Kinase-like LRR_8 PF13855.1 AIN98802.1 - 1.5e-05 24.6 1.8 0.011 15.4 0.0 3.4 2 1 2 4 4 4 2 Leucine rich repeat LRR_1 PF00560.28 AIN98802.1 - 3.8e-05 23.1 3.3 1.5 9.1 0.0 5.1 5 0 0 5 5 5 2 Leucine Rich Repeat C1_3 PF07649.7 AIN98802.1 - 6.9e-05 22.7 9.1 6.9e-05 22.7 6.3 2.7 2 0 0 2 2 2 1 C1-like domain LRR_4 PF12799.2 AIN98802.1 - 7.1e-05 22.3 0.4 0.53 9.9 0.0 4.0 2 1 2 4 4 4 2 Leucine Rich repeats (2 copies) zf-B_box PF00643.19 AIN98802.1 - 0.0028 17.5 3.8 0.0028 17.5 2.7 3.1 3 0 0 3 3 3 2 B-box zinc finger LRR_7 PF13504.1 AIN98802.1 - 0.0073 16.3 1.7 5.2 7.7 0.0 4.4 4 0 0 4 4 4 1 Leucine rich repeat ZZ PF00569.12 AIN98802.1 - 0.73 9.4 23.4 0.86 9.1 4.6 2.7 2 0 0 2 2 2 0 Zinc finger, ZZ type GCV_T PF01571.16 AIN98803.1 - 4.5e-16 58.8 0.0 6.8e-16 58.2 0.0 1.3 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.6 AIN98803.1 - 4.7e-11 42.5 0.2 8e-10 38.6 0.0 2.2 2 0 0 2 2 2 1 Glycine cleavage T-protein C-terminal barrel domain SET PF00856.23 AIN98804.1 - 6.9e-12 45.9 0.0 8.2e-10 39.2 0.0 2.3 2 0 0 2 2 2 2 SET domain Inhibitor_I42 PF09394.5 AIN98806.1 - 1.2e-21 76.7 0.1 1.5e-21 76.5 0.1 1.1 1 0 0 1 1 1 1 Chagasin family peptidase inhibitor I42 AMP-binding PF00501.23 AIN98807.1 - 9.7e-22 76.9 3.0 3.9e-11 41.9 0.1 3.7 3 1 0 3 3 3 3 AMP-binding enzyme DUF620 PF04788.7 AIN98807.1 - 0.0023 17.1 0.0 2.2 7.4 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF620) RRM_1 PF00076.17 AIN98808.1 - 1.1e-16 60.2 0.0 3.3e-16 58.6 0.0 1.8 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 AIN98808.1 - 1.4e-12 47.3 0.0 3.8e-12 45.9 0.0 1.7 1 1 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 AIN98808.1 - 2.5e-07 30.4 0.0 4.3e-07 29.6 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM PF05172.8 AIN98808.1 - 0.13 12.0 0.0 0.39 10.4 0.0 1.8 1 1 0 1 1 1 0 Nup53/35/40-type RNA recognition motif DUF1421 PF07223.6 AIN98808.1 - 0.25 11.0 34.0 0.33 10.6 23.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1421) PAT1 PF09770.4 AIN98808.1 - 2.5 6.2 27.8 3 5.9 19.3 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 adh_short PF00106.20 AIN98810.1 - 3.6e-16 59.5 2.2 3.6e-16 59.5 1.5 1.9 3 0 0 3 3 3 1 short chain dehydrogenase KR PF08659.5 AIN98810.1 - 1.8e-08 34.2 0.8 4e-08 33.1 0.5 1.6 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 AIN98810.1 - 0.00034 20.1 0.2 0.00053 19.5 0.1 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_7 PF13241.1 AIN98810.1 - 0.0053 16.9 0.1 0.015 15.5 0.1 1.7 1 0 0 1 1 1 1 Putative NAD(P)-binding THF_DHG_CYH_C PF02882.14 AIN98810.1 - 0.0064 15.5 0.3 0.21 10.6 0.0 2.8 3 0 0 3 3 3 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain NAD_binding_10 PF13460.1 AIN98810.1 - 0.012 15.5 0.9 0.012 15.5 0.6 2.4 2 1 0 2 2 2 0 NADH(P)-binding ArsA_ATPase PF02374.10 AIN98810.1 - 0.043 12.8 0.0 0.061 12.3 0.0 1.1 1 0 0 1 1 1 0 Anion-transporting ATPase ApbA PF02558.11 AIN98810.1 - 0.048 13.1 0.1 0.08 12.3 0.0 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA DFP PF04127.10 AIN98810.1 - 0.067 12.7 0.9 0.86 9.1 0.3 2.4 2 1 0 2 2 2 0 DNA / pantothenate metabolism flavoprotein adh_short PF00106.20 AIN98811.1 - 9.9e-17 61.3 0.1 9.8e-15 54.8 0.1 2.3 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 AIN98811.1 - 5.8e-08 32.6 0.0 1.1e-07 31.7 0.0 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 AIN98811.1 - 0.00081 18.8 0.0 0.0019 17.6 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short_C2 PF13561.1 AIN98811.1 - 0.0062 16.3 0.0 0.011 15.5 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 AIN98811.1 - 0.089 12.7 0.0 8.9 6.2 0.1 2.2 1 1 0 2 2 2 0 NADH(P)-binding NAD_binding_7 PF13241.1 AIN98811.1 - 0.1 12.8 0.0 0.31 11.3 0.0 1.9 2 0 0 2 2 2 0 Putative NAD(P)-binding WVELL PF14043.1 AIN98812.1 - 0.0021 17.6 0.4 0.0044 16.6 0.3 1.5 1 0 0 1 1 1 1 WVELL protein Amidase PF01425.16 AIN98812.1 - 0.095 11.5 0.1 0.13 11.1 0.1 1.1 1 0 0 1 1 1 0 Amidase Abhydrolase_2 PF02230.11 AIN98813.1 - 2.3e-40 138.3 0.0 2.8e-40 138.0 0.0 1.1 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_5 PF12695.2 AIN98813.1 - 1.1e-10 41.4 0.0 1.5e-10 41.0 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 AIN98813.1 - 4.2e-06 26.7 1.5 0.0027 17.6 0.5 2.3 1 1 1 2 2 2 2 Alpha/beta hydrolase family FSH1 PF03959.8 AIN98813.1 - 0.03 13.7 0.0 0.055 12.9 0.0 1.4 1 1 0 1 1 1 0 Serine hydrolase (FSH1) SPRY PF00622.23 AIN98816.1 - 0.0024 17.9 0.0 0.006 16.6 0.0 1.6 1 0 0 1 1 1 1 SPRY domain Cyclin PF08613.6 AIN98817.1 - 2.4e-17 63.7 0.1 4.6e-17 62.8 0.1 1.5 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.18 AIN98817.1 - 9.2e-09 34.9 0.1 1.7e-08 34.1 0.1 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.6 AIN98818.1 - 1.3e-20 74.3 0.0 2.4e-20 73.4 0.0 1.4 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.18 AIN98818.1 - 2.7e-07 30.2 0.2 4.4e-07 29.5 0.1 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain WD40 PF00400.27 AIN98819.1 - 1.4e-33 113.5 26.5 1.4e-08 34.2 0.0 8.1 8 1 0 8 8 8 6 WD domain, G-beta repeat PFU PF09070.6 AIN98819.1 - 3.4e-32 110.8 0.2 5.3e-32 110.2 0.2 1.3 1 0 0 1 1 1 1 PFU (PLAA family ubiquitin binding) AsnC_trans_reg PF01037.16 AIN98819.1 - 0.14 11.8 0.0 2.7 7.7 0.0 3.1 2 0 0 2 2 2 0 AsnC family PPTA PF01239.17 AIN98820.1 - 0.00064 18.9 12.8 0.18 11.2 0.1 4.3 4 0 0 4 4 4 2 Protein prenyltransferase alpha subunit repeat DnaJ PF00226.26 AIN98821.1 - 0.011 15.5 0.7 0.018 14.7 0.1 1.8 2 0 0 2 2 2 0 DnaJ domain Pam16 PF03656.8 AIN98821.1 - 0.13 12.1 0.2 0.23 11.2 0.1 1.7 1 1 0 1 1 1 0 Pam16 ADIP PF11559.3 AIN98822.1 - 0.96 9.3 26.8 0.61 9.9 4.4 3.2 3 0 0 3 3 3 0 Afadin- and alpha -actinin-Binding TSC22 PF01166.13 AIN98822.1 - 1.3 9.0 12.5 0.55 10.2 0.9 3.7 2 1 1 3 3 3 0 TSC-22/dip/bun family HAP1_N PF04849.8 AIN98822.1 - 1.8 7.4 21.0 0.1 11.5 7.2 2.3 2 0 0 2 2 2 0 HAP1 N-terminal conserved region DUF972 PF06156.8 AIN98822.1 - 2.1 8.7 15.6 2.9 8.2 0.4 3.7 3 1 1 4 4 4 0 Protein of unknown function (DUF972) RdRP_4 PF02123.11 AIN98822.1 - 4.4 5.9 7.4 0.67 8.6 1.9 1.8 2 0 0 2 2 2 0 Viral RNA-directed RNA-polymerase DUF724 PF05266.9 AIN98822.1 - 7.4 6.1 9.1 5.8 6.4 1.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF724) Ins134_P3_kin PF05770.6 AIN98823.1 - 4.7e-06 25.8 0.0 0.022 13.7 0.0 4.0 4 0 0 4 4 4 2 Inositol 1, 3, 4-trisphosphate 5/6-kinase DUF2217 PF10265.4 AIN98823.1 - 0.97 8.1 3.6 1.7 7.3 0.2 2.1 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2217) LIF_OSM PF01291.12 AIN98825.1 - 0.026 14.4 0.0 0.059 13.2 0.0 1.5 1 0 0 1 1 1 0 LIF / OSM family Tropomyosin PF00261.15 AIN98826.1 - 2.7 7.0 41.0 3 6.8 7.8 3.2 2 1 0 3 3 3 0 Tropomyosin TMF_DNA_bd PF12329.3 AIN98826.1 - 2.9 7.7 16.8 3.1 7.6 1.3 3.5 2 1 1 3 3 3 0 TATA element modulatory factor 1 DNA binding ERM PF00769.14 AIN98826.1 - 5.1 6.5 47.0 0.15 11.5 17.1 2.9 2 1 0 2 2 2 0 Ezrin/radixin/moesin family Seryl_tRNA_N PF02403.17 AIN98826.1 - 9.4 6.3 22.2 6.8 6.7 5.9 3.5 2 1 1 3 3 3 0 Seryl-tRNA synthetase N-terminal domain PD40 PF07676.7 AIN98827.1 - 0.037 13.6 0.0 0.09 12.4 0.0 1.6 1 0 0 1 1 1 0 WD40-like Beta Propeller Repeat STOP PF05217.7 AIN98828.1 - 1.7e-10 41.0 17.4 3.8e-05 23.5 0.8 3.5 1 1 1 2 2 2 2 STOP protein PRTP PF01366.13 AIN98829.1 - 8.5 4.2 6.7 15 3.3 4.6 1.3 1 0 0 1 1 1 0 Herpesvirus processing and transport protein PCIF1_WW PF12237.3 AIN98830.1 - 2.8e-08 33.2 0.0 9.4e-08 31.5 0.0 1.9 1 1 0 1 1 1 1 Phosphorylated CTD interacting factor 1 WW domain PI3_PI4_kinase PF00454.22 AIN98831.1 - 3.9e-42 144.3 0.0 9.5e-40 136.5 0.0 2.3 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.15 AIN98831.1 - 3.4e-23 81.7 0.0 7.8e-23 80.6 0.0 1.5 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3K_C2 PF00792.19 AIN98831.1 - 0.00043 20.0 0.0 0.0012 18.6 0.0 1.7 1 1 0 1 1 1 1 Phosphoinositide 3-kinase C2 DUF4135 PF13575.1 AIN98831.1 - 0.29 10.0 0.0 0.48 9.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4135) TFCD_C PF12612.3 AIN98832.1 - 5.4e-21 74.9 0.0 2.9e-20 72.5 0.0 2.3 1 1 0 1 1 1 1 Tubulin folding cofactor D C terminal HEAT_2 PF13646.1 AIN98832.1 - 1.2e-10 41.4 15.5 0.03 14.5 0.1 7.4 7 1 0 7 7 7 5 HEAT repeats HEAT PF02985.17 AIN98832.1 - 0.001 18.9 43.1 0.3 11.2 0.0 11.8 13 1 1 14 14 14 4 HEAT repeat Cnd1 PF12717.2 AIN98832.1 - 0.0023 17.8 0.3 9.2 6.0 0.0 4.8 5 0 0 5 5 5 1 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.1 AIN98832.1 - 0.026 15.0 37.4 0.15 12.6 0.6 9.5 9 1 1 10 10 10 0 HEAT-like repeat adh_short PF00106.20 AIN98833.1 - 1.2e-25 90.3 6.2 1.6e-25 89.9 4.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 AIN98833.1 - 4.8e-15 55.9 0.1 1.2e-14 54.7 0.1 1.5 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 AIN98833.1 - 1.1e-10 41.4 4.6 2.7e-10 40.1 3.1 1.6 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 AIN98833.1 - 5.2e-06 26.0 0.9 1e-05 25.1 0.6 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 AIN98833.1 - 2.7e-05 24.2 1.1 4.5e-05 23.5 0.8 1.3 1 0 0 1 1 1 1 NADH(P)-binding Shikimate_DH PF01488.15 AIN98833.1 - 0.00087 19.4 0.2 0.0023 18.0 0.1 1.6 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase DAO PF01266.19 AIN98833.1 - 0.0033 16.3 0.1 0.0042 16.0 0.1 1.3 1 1 0 1 1 1 1 FAD dependent oxidoreductase 3HCDH_N PF02737.13 AIN98833.1 - 0.0037 16.9 0.5 0.007 16.0 0.3 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Saccharop_dh PF03435.13 AIN98833.1 - 0.0046 15.9 0.5 0.0053 15.7 0.3 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase Polysacc_synt_2 PF02719.10 AIN98833.1 - 0.023 13.6 1.0 0.038 12.8 0.7 1.3 1 1 0 1 1 1 0 Polysaccharide biosynthesis protein ApbA PF02558.11 AIN98833.1 - 0.027 13.9 0.1 0.048 13.1 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA TrkA_N PF02254.13 AIN98833.1 - 0.034 14.1 1.3 0.047 13.6 0.1 1.7 2 0 0 2 2 2 0 TrkA-N domain FAD_binding_3 PF01494.14 AIN98833.1 - 0.037 13.0 0.1 0.061 12.3 0.1 1.3 1 0 0 1 1 1 0 FAD binding domain Eno-Rase_NADH_b PF12242.3 AIN98833.1 - 0.053 13.3 0.2 0.14 11.9 0.1 1.7 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase NAD_binding_4 PF07993.7 AIN98833.1 - 0.065 12.1 0.9 0.26 10.1 0.6 1.9 1 1 0 1 1 1 0 Male sterility protein NAD_binding_8 PF13450.1 AIN98833.1 - 0.077 13.0 0.1 0.21 11.6 0.1 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain DFP PF04127.10 AIN98833.1 - 0.11 12.0 1.7 0.23 11.0 0.2 1.9 2 0 0 2 2 2 0 DNA / pantothenate metabolism flavoprotein BolA PF01722.13 AIN98834.1 - 8.6e-17 60.8 0.0 1.2e-16 60.4 0.0 1.1 1 0 0 1 1 1 1 BolA-like protein KOW PF00467.24 AIN98835.1 - 1.5e-06 27.6 0.5 4.2e-06 26.2 0.3 1.9 1 1 0 1 1 1 1 KOW motif Transketolase_N PF00456.16 AIN98836.1 - 5e-135 449.6 0.1 6.5e-135 449.2 0.1 1.1 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.19 AIN98836.1 - 5e-45 153.1 0.0 9.6e-45 152.2 0.0 1.4 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.15 AIN98836.1 - 5.2e-09 36.1 0.0 1.2e-08 34.9 0.0 1.6 1 0 0 1 1 1 1 Transketolase, C-terminal domain DXP_synthase_N PF13292.1 AIN98836.1 - 3.3e-05 22.9 0.0 0.00032 19.7 0.0 2.1 1 1 1 2 2 2 1 1-deoxy-D-xylulose-5-phosphate synthase TPP_enzyme_C PF02775.16 AIN98836.1 - 0.00011 21.7 0.2 0.00054 19.5 0.1 2.2 1 1 1 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Terpene_synth PF01397.16 AIN98836.1 - 0.021 14.2 0.0 0.046 13.1 0.0 1.5 1 0 0 1 1 1 0 Terpene synthase, N-terminal domain E1_dh PF00676.15 AIN98836.1 - 0.08 11.6 0.0 0.14 10.8 0.0 1.4 1 0 0 1 1 1 0 Dehydrogenase E1 component Ribosomal_S8e PF01201.17 AIN98837.1 - 5.5e-45 152.7 2.8 6.4e-45 152.5 2.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S8e Kelch_3 PF13415.1 AIN98838.1 - 9.4e-49 162.5 7.8 2e-12 46.9 0.0 7.2 7 0 0 7 7 7 6 Galactose oxidase, central domain Kelch_4 PF13418.1 AIN98838.1 - 2.1e-41 139.4 20.0 1.1e-07 31.4 0.1 7.0 5 1 1 6 6 6 6 Galactose oxidase, central domain Kelch_1 PF01344.20 AIN98838.1 - 1.5e-32 110.8 20.3 1.2e-06 27.9 0.0 6.3 6 0 0 6 6 6 6 Kelch motif Kelch_5 PF13854.1 AIN98838.1 - 5.3e-31 106.0 14.4 2.7e-06 27.2 0.5 6.3 6 0 0 6 6 6 6 Kelch motif Kelch_6 PF13964.1 AIN98838.1 - 5.7e-31 105.4 11.0 5.8e-08 32.5 0.0 6.2 4 1 2 6 6 6 4 Kelch motif Kelch_2 PF07646.10 AIN98838.1 - 1.1e-26 91.5 15.3 1.5e-06 27.7 0.3 6.4 6 1 0 6 6 6 6 Kelch motif TPR_16 PF13432.1 AIN98839.1 - 1.7 9.3 12.2 0.13 13.0 4.0 2.4 2 1 1 3 3 3 0 Tetratricopeptide repeat HMG_CoA_synt_N PF01154.12 AIN98840.1 - 1.7e-11 43.9 0.1 3.5e-11 42.9 0.1 1.4 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal HMG_CoA_synt_C PF08540.5 AIN98840.1 - 1.1e-06 28.2 0.3 8.9e-05 22.0 0.0 2.4 2 1 0 2 2 2 1 Hydroxymethylglutaryl-coenzyme A synthase C terminal ACP_syn_III PF08545.5 AIN98840.1 - 0.0026 17.3 0.2 0.007 16.0 0.2 1.7 1 0 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III UQ_con PF00179.21 AIN98842.1 - 4.5e-44 149.2 0.2 4.9e-44 149.1 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 AIN98842.1 - 0.00025 20.9 0.1 0.00042 20.1 0.1 1.4 1 1 0 1 1 1 1 RWD domain UEV PF05743.8 AIN98842.1 - 0.00072 19.2 0.3 0.0012 18.5 0.2 1.4 1 1 0 1 1 1 1 UEV domain Prok-E2_B PF14461.1 AIN98842.1 - 0.036 13.7 0.1 0.05 13.3 0.0 1.2 1 0 0 1 1 1 0 Prokaryotic E2 family B UQ_con PF00179.21 AIN98843.1 - 3.4e-07 29.7 0.0 6.9e-07 28.7 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 AIN98843.1 - 0.0073 16.1 0.0 0.01 15.7 0.0 1.3 1 0 0 1 1 1 1 RWD domain Aminotran_5 PF00266.14 AIN98844.1 - 0.1 11.3 0.6 0.2 10.3 0.3 1.6 1 1 0 1 1 1 0 Aminotransferase class-V YwqJ-deaminase PF14431.1 AIN98844.1 - 0.23 11.2 1.4 0.29 11.0 1.0 1.3 1 1 0 1 1 1 0 YwqJ-like deaminase GDPD PF03009.12 AIN98845.1 - 3e-22 79.3 0.0 3.9e-22 78.9 0.0 1.1 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family DUF2450 PF10475.4 AIN98846.1 - 2.8e-16 59.2 6.2 2.8e-16 59.2 4.3 1.9 2 1 0 2 2 2 1 Protein of unknown function N-terminal domain (DUF2450) DUF2451 PF10474.4 AIN98846.1 - 6.3e-08 32.6 1.3 2.4e-07 30.7 0.2 2.3 2 0 0 2 2 2 1 Protein of unknown function C-terminus (DUF2451) Sec8_exocyst PF04048.9 AIN98846.1 - 0.0029 17.2 1.0 0.0068 16.0 0.7 1.6 1 0 0 1 1 1 1 Sec8 exocyst complex component specific domain Vps51 PF08700.6 AIN98846.1 - 0.063 13.1 0.1 0.17 11.7 0.1 1.7 1 0 0 1 1 1 0 Vps51/Vps67 FlxA PF14282.1 AIN98847.1 - 0.0021 17.9 7.3 0.0021 17.9 5.0 14.1 5 4 7 15 15 15 2 FlxA-like protein Filament PF00038.16 AIN98847.1 - 0.0049 16.3 11.4 0.0049 16.3 7.9 11.3 2 2 7 10 10 10 2 Intermediate filament protein DUF641 PF04859.7 AIN98847.1 - 0.0065 16.2 3.9 0.0065 16.2 2.7 15.0 7 4 6 16 16 16 2 Plant protein of unknown function (DUF641) Reo_sigmaC PF04582.7 AIN98847.1 - 0.008 15.3 0.1 0.008 15.3 0.1 10.2 2 2 10 12 12 12 5 Reovirus sigma C capsid protein NRN1 PF15056.1 AIN98847.1 - 0.073 13.0 12.7 0.58 10.1 0.1 5.2 4 0 0 4 4 4 0 Neuritin protein family DUF2140 PF09911.4 AIN98848.1 - 0.078 12.1 0.0 0.14 11.2 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2140) RskA PF10099.4 AIN98848.1 - 0.14 11.8 2.1 0.1 12.3 0.4 1.7 2 0 0 2 2 2 0 Anti-sigma-K factor rskA IncA PF04156.9 AIN98848.1 - 1 8.9 3.5 0.46 10.0 0.3 1.9 2 0 0 2 2 2 0 IncA protein PPR_2 PF13041.1 AIN98849.1 - 3.7e-07 30.0 0.0 0.012 15.5 0.0 3.4 2 1 1 3 3 3 3 PPR repeat family PPR_3 PF13812.1 AIN98849.1 - 7.6e-05 22.6 4.0 0.0043 17.2 0.0 4.0 4 1 0 4 4 4 1 Pentatricopeptide repeat domain PPR PF01535.15 AIN98849.1 - 0.014 15.3 0.0 9.5 6.4 0.0 3.3 3 0 0 3 3 3 0 PPR repeat Ribosomal_L11_N PF03946.9 AIN98850.1 - 6.9e-15 54.2 0.2 1.3e-14 53.4 0.1 1.5 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.14 AIN98850.1 - 1.1e-10 41.5 0.6 2e-10 40.6 0.4 1.5 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain DUF3671 PF12420.3 AIN98852.1 - 0.049 13.6 0.1 0.093 12.7 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function DUF1673 PF07895.6 AIN98852.1 - 0.64 9.5 3.6 2 7.9 0.2 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1673) Cob_adeno_trans PF01923.13 AIN98853.1 - 1.7e-46 157.9 0.3 2.6e-46 157.3 0.2 1.3 1 0 0 1 1 1 1 Cobalamin adenosyltransferase FA_desaturase PF00487.19 AIN98854.1 - 1e-13 51.3 19.9 1e-13 51.3 13.8 1.8 1 1 1 2 2 2 1 Fatty acid desaturase Cyt-b5 PF00173.23 AIN98854.1 - 5.4e-10 38.9 0.2 2.2e-07 30.5 0.1 2.9 1 1 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain WD40 PF00400.27 AIN98855.1 - 9.8e-77 250.3 28.1 6.1e-11 41.7 0.0 8.3 8 0 0 8 8 8 8 WD domain, G-beta repeat NLE PF08154.7 AIN98855.1 - 2e-15 56.5 0.0 3.3e-15 55.8 0.0 1.4 1 0 0 1 1 1 1 NLE (NUC135) domain eIF2A PF08662.6 AIN98855.1 - 7.3e-07 29.0 0.1 0.039 13.6 0.0 2.6 2 0 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A Nbas_N PF15492.1 AIN98855.1 - 0.00045 19.4 0.2 0.43 9.6 0.0 3.6 2 2 1 3 3 3 2 Neuroblastoma-amplified sequence, N terminal PD40 PF07676.7 AIN98855.1 - 0.00066 19.2 1.2 7.7 6.2 0.0 4.3 4 0 0 4 4 4 2 WD40-like Beta Propeller Repeat DUF1258 PF06869.7 AIN98855.1 - 0.081 11.9 0.2 3 6.8 0.0 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1258) zf-DHHC PF01529.15 AIN98856.1 - 1.3e-14 53.9 7.2 1.3e-14 53.9 5.0 2.5 2 2 0 2 2 2 1 DHHC palmitoyltransferase DUF3951 PF13131.1 AIN98856.1 - 1.3 8.8 8.4 0.34 10.7 0.8 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3951) DUF1227 PF06777.6 AIN98857.1 - 1.4e-44 151.3 0.2 3e-44 150.2 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1227) Helicase_C_2 PF13307.1 AIN98857.1 - 1.2e-39 135.9 0.0 2.6e-39 134.8 0.0 1.6 1 0 0 1 1 1 1 Helicase C-terminal domain DEAD_2 PF06733.10 AIN98857.1 - 4.7e-38 130.3 0.0 3.2e-37 127.6 0.0 2.2 2 0 0 2 2 2 1 DEAD_2 DEAD PF00270.24 AIN98857.1 - 0.00032 20.2 0.5 0.055 12.9 0.0 2.5 2 0 0 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.10 AIN98857.1 - 0.0026 17.6 0.5 0.031 14.0 0.0 2.4 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit Flavi_DEAD PF07652.9 AIN98857.1 - 0.012 15.3 0.8 0.61 9.8 0.1 2.6 2 0 0 2 2 2 0 Flavivirus DEAD domain Glyco_transf_21 PF13506.1 AIN98857.1 - 0.029 13.6 0.2 0.33 10.2 0.0 2.6 3 0 0 3 3 3 0 Glycosyl transferase family 21 AAA_19 PF13245.1 AIN98857.1 - 0.046 13.4 0.1 0.19 11.5 0.0 2.0 2 0 0 2 2 2 0 Part of AAA domain SNF2_N PF00176.18 AIN98857.1 - 0.1 11.3 0.1 0.7 8.6 0.1 2.0 1 1 0 1 1 1 0 SNF2 family N-terminal domain CorC_HlyC PF03471.12 AIN98857.1 - 0.13 12.0 0.0 0.36 10.6 0.0 1.7 1 0 0 1 1 1 0 Transporter associated domain Cullin PF00888.17 AIN98858.1 - 3.9e-70 237.0 0.0 5.2e-70 236.6 0.0 1.1 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.4 AIN98858.1 - 3.5e-26 90.8 0.4 1.9e-25 88.4 0.3 2.3 2 0 0 2 2 2 1 Cullin protein neddylation domain DUF2076 PF09849.4 AIN98860.1 - 0.086 12.8 0.5 0.086 12.8 0.4 1.4 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2076) Baculo_PEP_C PF04513.7 AIN98860.1 - 0.13 12.0 2.7 0.17 11.6 0.1 2.0 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF2051 PF09738.4 AIN98860.1 - 0.43 9.8 13.3 6.8 5.8 9.2 2.0 1 1 0 1 1 1 0 Double stranded RNA binding protein (DUF2051) AcylCoA_dehyd_C PF12186.3 AIN98860.1 - 2.1 8.2 8.6 0.39 10.5 1.0 2.4 1 1 1 2 2 2 0 Acyl-CoA dehydrogenase C terminal Mnd1 PF03962.10 AIN98860.1 - 2.2 7.9 12.1 38 3.8 8.4 2.0 1 1 0 1 1 1 0 Mnd1 family IncA PF04156.9 AIN98860.1 - 2.3 7.7 17.9 0.3 10.6 2.8 2.0 1 1 1 2 2 2 0 IncA protein FlxA PF14282.1 AIN98860.1 - 4.5 7.2 8.0 3.5 7.6 0.5 2.2 2 0 0 2 2 2 0 FlxA-like protein FlgN PF05130.7 AIN98860.1 - 5 7.3 14.2 12 6.1 8.8 1.9 1 1 1 2 2 2 0 FlgN protein Pkinase PF00069.20 AIN98861.1 - 5.1e-60 202.8 0.0 5.9e-60 202.5 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AIN98861.1 - 4e-41 140.7 0.0 5.2e-41 140.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 AIN98861.1 - 8.3e-05 21.6 0.0 0.0002 20.4 0.0 1.5 1 1 0 1 1 1 1 Kinase-like APH PF01636.18 AIN98861.1 - 0.15 11.8 0.0 0.2 11.3 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family SpoU_methylase PF00588.14 AIN98863.1 - 1e-15 57.8 0.1 2.6e-09 37.1 0.0 2.4 2 0 0 2 2 2 2 SpoU rRNA Methylase family DUF2442 PF10387.4 AIN98863.1 - 0.056 13.4 0.2 0.24 11.4 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2442) Glycos_transf_2 PF00535.21 AIN98867.1 - 1.3e-08 34.6 0.0 2.6e-08 33.7 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_2 PF10111.4 AIN98867.1 - 0.0043 16.1 0.0 1 8.3 0.0 2.2 2 0 0 2 2 2 2 Glycosyltransferase like family 2 Acetyltransf_1 PF00583.19 AIN98868.1 - 6.8e-09 35.6 0.1 1.2e-08 34.8 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.5 AIN98868.1 - 3.8e-07 29.7 0.0 5.5e-07 29.2 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.1 AIN98868.1 - 0.082 13.0 0.0 0.13 12.3 0.0 1.4 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain DUF2431 PF10354.4 AIN98869.1 - 4.6e-20 72.2 0.0 4.4e-15 56.0 0.0 2.3 1 1 1 2 2 2 2 Domain of unknown function (DUF2431) zf-C2H2_jaz PF12171.3 AIN98869.1 - 3.4e-05 23.8 5.2 0.0025 17.9 0.3 3.5 3 0 0 3 3 3 1 Zinc-finger double-stranded RNA-binding zf-C2H2 PF00096.21 AIN98869.1 - 4.7e-05 23.4 9.6 0.053 13.8 0.3 3.9 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 AIN98869.1 - 0.00018 21.6 11.0 0.55 10.6 0.6 4.0 3 0 0 3 3 3 3 C2H2-type zinc finger zf-met PF12874.2 AIN98869.1 - 0.0012 18.9 0.1 0.0012 18.9 0.1 3.0 2 1 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.1 AIN98869.1 - 0.0034 17.2 5.6 0.0038 17.0 0.0 3.4 3 1 0 3 3 3 1 C2H2-type zinc finger zf-DBF PF07535.7 AIN98869.1 - 0.12 12.0 0.3 0.27 10.9 0.2 1.6 1 0 0 1 1 1 0 DBF zinc finger zf-C2H2_2 PF12756.2 AIN98869.1 - 0.69 10.0 3.1 1.4 9.0 0.2 2.4 2 1 0 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-met2 PF12907.2 AIN98869.1 - 1.5 8.8 4.9 20 5.2 0.0 2.8 3 0 0 3 3 3 0 Zinc-binding DUF972 PF06156.8 AIN98870.1 - 0.012 15.9 0.5 0.012 15.9 0.3 3.8 3 1 1 4 4 4 0 Protein of unknown function (DUF972) Reo_sigmaC PF04582.7 AIN98870.1 - 0.042 13.0 0.2 0.079 12.1 0.1 1.3 1 0 0 1 1 1 0 Reovirus sigma C capsid protein TSC22 PF01166.13 AIN98870.1 - 0.078 12.9 4.7 0.66 9.9 0.9 3.0 1 1 1 2 2 2 0 TSC-22/dip/bun family V_ATPase_I PF01496.14 AIN98870.1 - 7.9 4.1 4.7 12 3.6 1.5 2.1 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family CEP44 PF15007.1 AIN98871.1 - 0.00011 21.9 0.0 0.00015 21.5 0.0 1.2 1 0 0 1 1 1 1 Centrosomal spindle body, CEP44 Got1 PF04178.7 AIN98872.1 - 1.8e-25 89.3 15.4 2.8e-25 88.6 10.7 1.3 1 0 0 1 1 1 1 Got1/Sft2-like family AzlD PF05437.7 AIN98872.1 - 0.023 14.6 4.6 0.023 14.6 3.2 2.0 1 1 1 2 2 2 0 Branched-chain amino acid transport protein (AzlD) DUF3270 PF11674.3 AIN98872.1 - 3.6 7.6 7.4 0.78 9.7 0.2 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF3270) RRM_1 PF00076.17 AIN98874.1 - 3.6e-63 209.1 0.7 4.8e-20 70.9 0.0 4.4 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 AIN98874.1 - 4.6e-46 154.6 0.5 1.7e-15 56.7 0.0 4.6 5 0 0 5 5 5 4 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 AIN98874.1 - 6.3e-32 109.2 0.3 4.5e-11 42.4 0.0 4.4 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP PF00658.13 AIN98874.1 - 4.7e-19 67.8 0.1 1e-18 66.7 0.1 1.6 1 0 0 1 1 1 1 Poly-adenylate binding protein, unique domain OB_RNB PF08206.6 AIN98874.1 - 0.047 13.2 0.5 0.7 9.4 0.0 2.5 2 0 0 2 2 2 0 Ribonuclease B OB domain Phage_B PF02304.10 AIN98874.1 - 0.056 13.7 0.0 0.14 12.4 0.0 1.6 1 0 0 1 1 1 0 Scaffold protein B DUF4651 PF15513.1 AIN98874.1 - 0.14 11.5 0.1 25 4.3 0.0 3.7 4 0 0 4 4 4 0 Domain of unknown function (DUF4651) SNARE PF05739.14 AIN98875.1 - 1.4e-07 31.1 0.6 2.6e-07 30.1 0.4 1.4 1 0 0 1 1 1 1 SNARE domain Filament PF00038.16 AIN98875.1 - 0.0031 17.0 0.8 0.0037 16.7 0.6 1.0 1 0 0 1 1 1 1 Intermediate filament protein Laminin_II PF06009.7 AIN98875.1 - 0.0031 17.2 0.9 0.0041 16.8 0.5 1.3 1 1 0 1 1 1 1 Laminin Domain II RPAP1_N PF08621.5 AIN98875.1 - 0.0063 16.0 4.4 0.2 11.2 0.4 2.1 2 0 0 2 2 2 2 RPAP1-like, N-terminal Rho_Binding PF08912.6 AIN98875.1 - 0.022 15.0 1.0 0.089 13.1 0.3 1.9 1 1 1 2 2 2 0 Rho Binding DUF745 PF05335.8 AIN98875.1 - 0.03 13.8 2.0 0.038 13.5 1.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF745) Sec20 PF03908.8 AIN98875.1 - 0.033 13.8 1.4 0.33 10.6 0.5 2.0 1 1 1 2 2 2 0 Sec20 DUF812 PF05667.6 AIN98875.1 - 0.039 12.4 2.7 0.045 12.2 1.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF812) DUF4254 PF14063.1 AIN98875.1 - 0.042 13.4 0.9 0.058 13.0 0.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4254) TPR_MLP1_2 PF07926.7 AIN98875.1 - 0.05 13.3 3.6 0.064 12.9 2.5 1.1 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein DUF3450 PF11932.3 AIN98875.1 - 0.053 12.7 1.1 0.062 12.5 0.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) GLE1 PF07817.8 AIN98875.1 - 0.055 12.3 0.3 0.072 12.0 0.2 1.1 1 0 0 1 1 1 0 GLE1-like protein DUF1664 PF07889.7 AIN98875.1 - 0.062 13.1 0.2 0.098 12.4 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) R3H-assoc PF13902.1 AIN98875.1 - 0.073 13.0 0.1 0.089 12.7 0.1 1.2 1 0 0 1 1 1 0 R3H-associated N-terminal domain BAR_3_WASP_bdg PF10456.4 AIN98875.1 - 0.098 11.8 0.1 0.11 11.6 0.1 1.1 1 0 0 1 1 1 0 WASP-binding domain of Sorting nexin protein DUF364 PF04016.7 AIN98876.1 - 0.043 13.1 0.0 0.049 12.9 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF364) ETF PF01012.16 AIN98878.1 - 9.4e-38 129.4 2.5 1.2e-37 129.1 1.8 1.1 1 0 0 1 1 1 1 Electron transfer flavoprotein domain GTP_EFTU PF00009.22 AIN98879.1 - 3.4e-49 166.8 0.1 5e-49 166.2 0.1 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.19 AIN98879.1 - 8.1e-13 48.0 0.0 2e-12 46.7 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus Septin PF00735.13 AIN98879.1 - 1.1e-05 24.5 0.1 1.9e-05 23.8 0.1 1.3 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.18 AIN98879.1 - 9.5e-05 22.3 0.1 0.00019 21.3 0.1 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_10 PF12846.2 AIN98879.1 - 0.00099 18.6 0.2 0.0022 17.4 0.1 1.6 1 1 0 1 1 1 1 AAA-like domain Miro PF08477.8 AIN98879.1 - 0.0029 18.1 0.0 0.006 17.0 0.0 1.6 1 0 0 1 1 1 1 Miro-like protein EFG_II PF14492.1 AIN98879.1 - 0.005 16.6 0.0 0.017 14.9 0.0 2.0 1 0 0 1 1 1 1 Elongation Factor G, domain II GTP_EFTU_D2 PF03144.20 AIN98879.1 - 0.046 13.8 0.0 0.14 12.3 0.0 1.8 1 0 0 1 1 1 0 Elongation factor Tu domain 2 RnfC_N PF13375.1 AIN98879.1 - 0.084 12.5 0.1 0.91 9.2 0.0 2.6 2 0 0 2 2 2 0 RnfC Barrel sandwich hybrid domain RNA_pol_Rpb6 PF01192.17 AIN98880.1 - 3.7e-10 39.3 0.0 5.8e-10 38.7 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb6 DivIC PF04977.10 AIN98882.1 - 0.099 12.1 5.9 0.2 11.1 0.1 3.0 2 1 0 2 2 2 0 Septum formation initiator TPR_MLP1_2 PF07926.7 AIN98882.1 - 0.82 9.4 5.8 0.55 9.9 1.3 2.2 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein CPSF100_C PF13299.1 AIN98883.1 - 4.2e-22 79.0 0.3 7.7e-22 78.1 0.0 1.6 2 0 0 2 2 2 1 Cleavage and polyadenylation factor 2 C-terminal Beta-Casp PF10996.3 AIN98883.1 - 2.2e-10 40.5 0.0 1.3e-09 38.0 0.0 2.1 2 0 0 2 2 2 1 Beta-Casp domain Lactamase_B PF00753.22 AIN98883.1 - 4.9e-06 26.3 1.3 8.9e-06 25.4 0.2 1.9 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily Peptidase_C12 PF01088.16 AIN98885.1 - 2.9e-57 193.3 0.0 3.2e-57 193.1 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 Clathrin PF00637.15 AIN98886.1 - 2.1e-07 30.6 2.2 0.00016 21.2 0.2 3.8 4 0 0 4 4 4 2 Region in Clathrin and VPS TPR_14 PF13428.1 AIN98886.1 - 0.00014 22.1 3.2 26 5.8 0.0 6.2 6 0 0 6 6 6 0 Tetratricopeptide repeat Apc4_WD40 PF12894.2 AIN98886.1 - 0.014 14.8 0.0 0.084 12.3 0.0 2.2 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain TPR_7 PF13176.1 AIN98886.1 - 0.02 14.6 8.8 3.3 7.7 0.1 6.0 6 0 0 6 6 6 0 Tetratricopeptide repeat KNOX2 PF03791.8 AIN98886.1 - 0.051 12.8 0.0 0.14 11.4 0.0 1.7 1 0 0 1 1 1 0 KNOX2 domain WD40 PF00400.27 AIN98886.1 - 0.053 13.4 6.1 12 5.9 0.3 4.6 5 0 0 5 5 5 0 WD domain, G-beta repeat TPR_19 PF14559.1 AIN98886.1 - 0.5 10.7 10.5 0.72 10.2 0.0 5.4 5 2 1 6 6 6 0 Tetratricopeptide repeat TPR_11 PF13414.1 AIN98886.1 - 0.83 9.3 0.0 0.83 9.3 0.0 6.0 8 0 0 8 8 8 0 TPR repeat DZR PF12773.2 AIN98886.1 - 1.1 9.1 5.9 3.4 7.5 4.1 1.9 1 0 0 1 1 1 0 Double zinc ribbon TPR_12 PF13424.1 AIN98886.1 - 2.4 8.1 16.4 3.9 7.4 0.5 5.9 4 2 3 7 7 7 0 Tetratricopeptide repeat Apc3 PF12895.2 AIN98886.1 - 4.7 7.4 12.3 2.9 8.0 1.3 5.0 3 3 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 Mito_carr PF00153.22 AIN98887.1 - 2.8e-62 206.4 0.9 5.5e-20 70.8 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein GRP PF07172.6 AIN98888.1 - 0.32 11.4 18.8 0.43 11.0 10.5 2.4 2 0 0 2 2 2 0 Glycine rich protein family DSPc PF00782.15 AIN98889.1 - 7.4e-16 57.9 0.1 1.2e-15 57.2 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.1 AIN98889.1 - 2.1e-06 27.8 0.7 3.3e-06 27.2 0.1 1.5 2 0 0 2 2 2 1 Inositol hexakisphosphate Y_phosphatase PF00102.22 AIN98889.1 - 0.00018 20.9 0.4 0.00025 20.4 0.3 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.1 AIN98889.1 - 0.001 19.3 0.1 0.0025 18.1 0.0 1.7 1 0 0 1 1 1 1 Tyrosine phosphatase family CDKN3 PF05706.7 AIN98889.1 - 0.012 15.1 0.1 0.02 14.3 0.1 1.3 1 0 0 1 1 1 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) Bud13 PF09736.4 AIN98890.1 - 1.2e-05 25.5 0.0 1.8e-05 25.0 0.0 1.3 1 0 0 1 1 1 1 Pre-mRNA-splicing factor of RES complex Mating_C PF12737.2 AIN98890.1 - 0.06 12.2 0.4 0.077 11.8 0.3 1.1 1 0 0 1 1 1 0 C-terminal domain of homeodomain 1 DUF3135 PF11333.3 AIN98891.1 - 0.016 15.3 5.7 0.77 9.9 0.8 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3135) Dynein_light PF01221.13 AIN98892.1 - 2.4e-36 123.5 0.4 2.6e-36 123.4 0.3 1.0 1 0 0 1 1 1 1 Dynein light chain type 1 NSP13 PF06460.7 AIN98893.1 - 0.036 12.9 0.0 0.075 11.8 0.0 1.4 1 0 0 1 1 1 0 Coronavirus NSP13 TBPIP PF07106.8 AIN98893.1 - 9.6 5.7 38.1 0.064 12.8 1.1 5.8 6 1 0 6 6 6 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Reo_sigmaC PF04582.7 AIN98894.1 - 0.28 10.3 4.4 2.1 7.4 0.1 2.3 2 0 0 2 2 2 0 Reovirus sigma C capsid protein GAS PF13851.1 AIN98894.1 - 4.1 6.5 18.4 0.063 12.4 5.6 2.5 3 0 0 3 3 3 0 Growth-arrest specific micro-tubule binding CENP-F_leu_zip PF10473.4 AIN98894.1 - 5.5 6.8 29.9 0.11 12.4 10.7 3.3 3 0 0 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DivIC PF04977.10 AIN98894.1 - 7.3 6.1 19.9 0.027 13.9 3.4 3.0 3 1 0 3 3 3 0 Septum formation initiator V_ATPase_I PF01496.14 AIN98894.1 - 7.4 4.2 6.8 3.2 5.5 3.0 1.6 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family RRM_1 PF00076.17 AIN98895.1 - 4.4e-05 23.0 0.1 0.0023 17.5 0.0 2.4 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 AIN98895.1 - 0.0028 17.5 0.0 0.014 15.3 0.0 2.0 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) ATP_bind_4 PF01902.12 AIN98896.1 - 2.2e-31 108.9 0.1 5.8e-29 101.0 0.1 3.0 1 1 0 1 1 1 1 ATP-binding region DUF2892 PF11127.3 AIN98897.1 - 0.11 12.2 0.1 0.16 11.8 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2892) B9-C2 PF07162.6 AIN98899.1 - 1.5e-11 44.3 0.1 2.4e-11 43.7 0.1 1.3 1 0 0 1 1 1 1 Ciliary basal body-associated, B9 protein SPRY PF00622.23 AIN98900.1 - 0.00025 21.1 0.0 0.00043 20.3 0.0 1.3 1 0 0 1 1 1 1 SPRY domain DUF1308 PF07000.6 AIN98901.1 - 7.1e-136 452.5 0.1 8.9e-136 452.2 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1308) Fcf2 PF08698.6 AIN98903.1 - 2.1e-19 69.3 0.6 2.1e-19 69.3 0.4 2.1 2 1 1 3 3 3 1 Fcf2 pre-rRNA processing DUF2407_C PF13373.1 AIN98903.1 - 0.093 12.6 0.4 0.15 12.0 0.2 1.4 1 0 0 1 1 1 0 DUF2407 C-terminal domain TGT_C1 PF14809.1 AIN98906.1 - 0.027 14.2 0.0 0.036 13.8 0.0 1.2 1 0 0 1 1 1 0 C1 domain of tRNA-guanine transglycosylase dimerisation SUI1 PF01253.17 AIN98907.1 - 3.3e-19 68.4 0.1 6e-19 67.6 0.1 1.5 1 0 0 1 1 1 1 Translation initiation factor SUI1 Baculo_PEP_C PF04513.7 AIN98908.1 - 7 6.4 43.3 0.14 11.9 0.3 7.4 4 1 3 8 8 8 0 Baculovirus polyhedron envelope protein, PEP, C terminus WD40 PF00400.27 AIN98909.1 - 6.1e-50 165.4 15.0 1.7e-09 37.1 0.0 9.5 10 0 0 10 10 10 7 WD domain, G-beta repeat Utp13 PF08625.6 AIN98909.1 - 6.7e-37 126.2 0.6 1.2e-36 125.4 0.4 1.3 1 0 0 1 1 1 1 Utp13 specific WD40 associated domain Nup160 PF11715.3 AIN98909.1 - 0.0017 16.5 6.0 0.96 7.5 0.0 3.8 3 1 1 4 4 4 2 Nucleoporin Nup120/160 Utp12 PF04003.7 AIN98909.1 - 0.004 17.0 0.2 0.017 15.0 0.1 2.0 2 0 0 2 2 2 1 Dip2/Utp12 Family HCV_NS5a_1b PF08301.8 AIN98909.1 - 0.0081 16.5 0.1 0.03 14.6 0.1 2.0 1 0 0 1 1 1 1 Hepatitis C virus non-structural 5a domain 1b UTP15_C PF09384.5 AIN98909.1 - 0.063 12.9 0.9 0.13 11.9 0.6 1.5 1 0 0 1 1 1 0 UTP15 C terminal Nucleoporin_N PF08801.6 AIN98909.1 - 0.12 11.0 1.7 1.9 7.1 0.3 3.3 2 1 0 2 2 2 0 Nup133 N terminal like TFIIB PF00382.14 AIN98910.1 - 9e-24 83.0 0.1 1.3e-11 44.1 0.0 2.5 2 0 0 2 2 2 2 Transcription factor TFIIB repeat TF_Zn_Ribbon PF08271.7 AIN98910.1 - 0.042 13.1 0.1 0.095 12.0 0.1 1.6 1 0 0 1 1 1 0 TFIIB zinc-binding MMR_HSR1 PF01926.18 AIN98911.1 - 1.3e-13 50.9 0.0 2.2e-13 50.1 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 AIN98911.1 - 1.3e-07 31.0 0.0 9.3e-06 25.0 0.0 2.2 2 0 0 2 2 2 1 Ferrous iron transport protein B DUF258 PF03193.11 AIN98911.1 - 7.5e-06 25.2 0.0 1.6e-05 24.1 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Dynamin_N PF00350.18 AIN98911.1 - 0.00014 21.7 0.7 0.067 13.0 0.1 2.4 1 1 1 2 2 2 2 Dynamin family AIG1 PF04548.11 AIN98911.1 - 0.00044 19.4 0.0 0.00075 18.6 0.0 1.4 1 0 0 1 1 1 1 AIG1 family GTP_EFTU PF00009.22 AIN98911.1 - 0.0019 17.6 0.0 0.11 11.8 0.0 2.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.5 AIN98911.1 - 0.0083 15.3 0.0 0.013 14.6 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.7 AIN98911.1 - 0.088 11.9 0.0 0.12 11.4 0.0 1.3 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region Kringle PF00051.13 AIN98913.1 - 4e-15 55.6 0.4 7.9e-15 54.7 0.3 1.5 1 0 0 1 1 1 1 Kringle domain CHB_HEX_C_1 PF13290.1 AIN98913.1 - 9.7e-05 22.0 1.4 0.00064 19.4 0.1 2.8 2 0 0 2 2 2 1 Chitobiase/beta-hexosaminidase C-terminal domain CHB_HEX_C PF03174.8 AIN98913.1 - 0.00036 20.3 0.1 0.00036 20.3 0.1 3.2 4 0 0 4 4 4 1 Chitobiase/beta-hexosaminidase C-terminal domain Fn3_assoc PF13287.1 AIN98913.1 - 0.0075 16.3 0.2 0.069 13.2 0.0 2.7 2 0 0 2 2 2 1 Fn3 associated RRM_1 PF00076.17 AIN98915.1 - 4.2e-21 74.3 0.0 5.5e-21 73.9 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 AIN98915.1 - 3.8e-15 55.6 0.0 5.7e-15 55.0 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 AIN98915.1 - 9.4e-13 47.8 0.1 1.4e-12 47.2 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 AIN98916.1 - 4.3e-21 74.3 0.0 5.6e-21 73.9 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 AIN98916.1 - 3.9e-15 55.5 0.0 5.8e-15 55.0 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 AIN98916.1 - 9.5e-13 47.7 0.1 1.4e-12 47.2 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 AIN98918.1 - 1.1e-17 63.3 0.3 5.2e-17 61.2 0.0 2.1 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 AIN98918.1 - 2.5e-12 46.6 0.3 8.9e-12 44.8 0.0 2.1 3 0 0 3 3 3 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 AIN98918.1 - 5.4e-07 29.3 0.6 1.4e-06 28.0 0.4 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) ABC_membrane PF00664.18 AIN98919.1 - 4.2e-47 160.8 3.7 5.8e-47 160.3 2.5 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.22 AIN98919.1 - 9.5e-34 116.6 0.0 1.7e-33 115.8 0.0 1.4 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.14 AIN98919.1 - 2.9e-05 23.3 0.1 0.044 13.0 0.0 2.2 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA PF00004.24 AIN98919.1 - 0.00046 20.3 0.1 0.0075 16.4 0.1 2.2 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 AIN98919.1 - 0.00066 19.7 1.6 0.003 17.5 1.1 2.0 1 1 0 1 1 1 1 AAA ATPase domain AAA_21 PF13304.1 AIN98919.1 - 0.0013 18.7 0.0 1.3 8.9 0.0 2.2 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.1 AIN98919.1 - 0.0018 18.4 0.6 0.028 14.5 0.3 2.6 1 1 0 1 1 1 1 AAA domain ABC_ATPase PF09818.4 AIN98919.1 - 0.0036 15.9 0.1 0.0069 15.0 0.1 1.3 1 0 0 1 1 1 1 Predicted ATPase of the ABC class AAA_5 PF07728.9 AIN98919.1 - 0.015 15.0 0.2 0.19 11.4 0.0 2.5 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) AAA_29 PF13555.1 AIN98919.1 - 0.026 14.0 0.0 0.063 12.8 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF258 PF03193.11 AIN98919.1 - 0.038 13.1 0.0 0.11 11.6 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function, DUF258 Zeta_toxin PF06414.7 AIN98919.1 - 0.064 12.3 0.0 0.13 11.3 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_17 PF13207.1 AIN98919.1 - 0.067 14.0 0.0 0.14 12.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_10 PF12846.2 AIN98919.1 - 0.083 12.3 0.7 0.26 10.6 0.5 1.9 1 1 0 1 1 1 0 AAA-like domain DUF87 PF01935.12 AIN98919.1 - 0.093 12.5 0.1 0.24 11.1 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function DUF87 AAA_25 PF13481.1 AIN98919.1 - 0.11 11.8 0.1 0.95 8.8 0.0 2.1 2 0 0 2 2 2 0 AAA domain LSM14 PF12701.2 AIN98920.1 - 4.5e-31 106.5 0.0 7e-31 105.9 0.0 1.3 1 0 0 1 1 1 1 Scd6-like Sm domain FDF PF09532.5 AIN98920.1 - 7.7e-06 26.3 16.2 0.0039 17.7 3.7 2.4 1 1 1 2 2 2 2 FDF domain SM-ATX PF14438.1 AIN98920.1 - 1.1e-05 25.2 0.1 1.8e-05 24.5 0.0 1.4 1 0 0 1 1 1 1 Ataxin 2 SM domain DnaJ PF00226.26 AIN98922.1 - 0.00088 18.9 0.1 0.0018 17.9 0.1 1.5 1 0 0 1 1 1 1 DnaJ domain SP_C-Propep PF08999.5 AIN98922.1 - 0.026 13.9 0.3 0.045 13.2 0.2 1.3 1 0 0 1 1 1 0 Surfactant protein C, N terminal propeptide HAMP PF00672.20 AIN98922.1 - 0.26 11.5 3.1 0.45 10.7 2.2 1.4 1 0 0 1 1 1 0 HAMP domain Y_phosphatase2 PF03162.8 AIN98923.1 - 5.7e-35 120.1 0.0 1.1e-26 93.1 0.0 2.1 2 0 0 2 2 2 2 Tyrosine phosphatase family Y_phosphatase3 PF13350.1 AIN98923.1 - 0.00073 19.8 0.0 0.0012 19.0 0.0 1.3 1 0 0 1 1 1 1 Tyrosine phosphatase family Ins_beta PF03488.9 AIN98924.1 - 0.061 13.1 0.1 0.15 11.8 0.0 1.6 2 0 0 2 2 2 0 Nematode insulin-related peptide beta type DUF2475 PF10629.4 AIN98925.1 - 0.017 15.3 1.1 0.017 15.3 0.8 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2475) Raptor_N PF14538.1 AIN98926.1 - 1.1e-46 158.4 0.0 2.9e-46 157.1 0.0 1.8 1 0 0 1 1 1 1 Raptor N-terminal CASPase like domain HEAT PF02985.17 AIN98926.1 - 0.00074 19.4 5.3 0.082 13.0 0.1 3.6 3 0 0 3 3 3 2 HEAT repeat HEAT_2 PF13646.1 AIN98926.1 - 0.0053 17.0 0.2 0.1 12.8 0.0 2.6 2 1 1 3 3 3 2 HEAT repeats RNA_pol_Rpb2_6 PF00562.23 AIN98927.1 - 1.5e-93 313.5 0.0 2.2e-93 313.1 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpa2_4 PF06883.7 AIN98927.1 - 6.1e-18 64.5 0.0 1.7e-17 63.1 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase I, Rpa2 specific domain RNA_pol_Rpb2_3 PF04565.11 AIN98927.1 - 1.3e-15 56.8 0.0 3e-15 55.7 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_7 PF04560.15 AIN98927.1 - 2.3e-13 50.1 0.0 8.7e-13 48.3 0.0 2.1 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_1 PF04563.10 AIN98927.1 - 1.6e-08 33.6 0.0 4.6e-08 32.2 0.0 1.7 2 0 0 2 2 2 1 RNA polymerase beta subunit zf-ribbon_3 PF13248.1 AIN98927.1 - 0.14 11.3 0.4 0.49 9.6 0.3 2.0 1 0 0 1 1 1 0 zinc-ribbon domain SEO_C PF14577.1 AIN98927.1 - 0.23 10.7 0.2 0.46 9.8 0.2 1.4 1 0 0 1 1 1 0 Sieve element occlusion C-terminus PPR PF01535.15 AIN98928.1 - 6e-05 22.7 0.2 0.00052 19.8 0.0 2.4 2 0 0 2 2 2 1 PPR repeat PPR_2 PF13041.1 AIN98928.1 - 0.00012 21.9 0.7 0.0013 18.6 0.0 2.7 3 0 0 3 3 3 1 PPR repeat family PPR_1 PF12854.2 AIN98928.1 - 0.0009 18.6 0.0 0.0028 17.0 0.0 1.9 1 0 0 1 1 1 1 PPR repeat GTSE1_N PF15259.1 AIN98929.1 - 0.092 12.6 0.0 0.16 11.8 0.0 1.4 1 0 0 1 1 1 0 G-2 and S-phase expressed 1 zf-AN1 PF01428.11 AIN98930.1 - 1.8e-05 24.5 23.4 0.00057 19.6 4.7 2.4 2 0 0 2 2 2 2 AN1-like Zinc finger ENTH PF01417.15 AIN98932.1 - 2.6e-26 91.9 0.0 4e-26 91.3 0.0 1.3 1 0 0 1 1 1 1 ENTH domain Alpha_kinase PF02816.13 AIN98933.1 - 2.6e-53 180.5 0.0 5.1e-52 176.2 0.0 2.1 2 0 0 2 2 2 2 Alpha-kinase family SCAMP PF04144.8 AIN98937.1 - 8.8e-28 97.3 11.6 1.3e-27 96.8 8.1 1.2 1 0 0 1 1 1 1 SCAMP family SNF2_N PF00176.18 AIN98939.1 - 3.5e-63 213.1 0.1 1.6e-32 112.4 0.0 2.9 2 1 0 2 2 2 2 SNF2 family N-terminal domain zf-PARP PF00645.13 AIN98939.1 - 2.1e-16 59.9 0.4 5.8e-16 58.5 0.2 1.8 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region Helicase_C PF00271.26 AIN98939.1 - 1e-13 50.9 0.7 4.2e-13 48.9 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain zf-RING_2 PF13639.1 AIN98939.1 - 2e-06 27.5 4.2 2e-06 27.5 2.9 2.8 3 0 0 3 3 3 1 Ring finger domain zf-C3HC4 PF00097.20 AIN98939.1 - 0.00063 19.3 3.1 0.00063 19.3 2.2 3.3 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) ResIII PF04851.10 AIN98939.1 - 0.0037 17.1 0.0 1.9 8.2 0.0 2.6 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit zf-rbx1 PF12678.2 AIN98939.1 - 0.012 15.7 1.6 0.04 14.0 1.1 1.9 1 0 0 1 1 1 0 RING-H2 zinc finger PHD PF00628.24 AIN98939.1 - 0.013 15.2 2.4 0.013 15.2 1.7 3.9 5 0 0 5 5 5 0 PHD-finger PP2C PF00481.16 AIN98940.1 - 2.9e-52 177.6 0.0 3.7e-52 177.2 0.0 1.1 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.1 AIN98940.1 - 0.00052 19.4 0.0 0.00094 18.6 0.0 1.4 1 0 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.7 AIN98940.1 - 0.00095 18.9 0.0 0.013 15.1 0.0 2.2 2 0 0 2 2 2 1 Stage II sporulation protein E (SpoIIE) TIP39 PF14980.1 AIN98940.1 - 0.028 14.0 0.0 0.067 12.8 0.0 1.6 1 0 0 1 1 1 0 TIP39 peptide Mito_fiss_reg PF05308.6 AIN98942.1 - 0.52 9.6 2.9 0.84 8.9 2.0 1.3 1 0 0 1 1 1 0 Mitochondrial fission regulator Ank_2 PF12796.2 AIN98944.1 - 2.6e-08 34.0 0.1 0.00065 19.9 0.0 4.0 2 2 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 AIN98944.1 - 0.00017 21.9 2.9 0.41 11.2 0.0 4.7 4 2 0 4 4 4 2 Ankyrin repeats (many copies) Ank PF00023.25 AIN98944.1 - 0.00034 20.2 3.6 0.0011 18.6 0.0 3.7 5 0 0 5 5 5 1 Ankyrin repeat Ank_3 PF13606.1 AIN98944.1 - 0.0026 17.8 3.4 0.15 12.3 0.0 5.2 7 0 0 7 7 7 1 Ankyrin repeat Ank_5 PF13857.1 AIN98944.1 - 0.0034 17.5 5.1 0.052 13.8 0.2 4.4 4 1 1 5 5 5 1 Ankyrin repeats (many copies) zf-DNL PF05180.7 AIN98945.1 - 6.3e-29 99.5 0.1 1e-28 98.8 0.1 1.3 1 0 0 1 1 1 1 DNL zinc finger HET-s_218-289 PF11558.3 AIN98945.1 - 0.05 13.5 0.0 0.089 12.7 0.0 1.5 1 0 0 1 1 1 0 Het-s 218-289 zf-RING_4 PF14570.1 AIN98945.1 - 0.092 12.3 0.5 0.17 11.4 0.3 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain CSTF_C PF14304.1 AIN98945.1 - 0.1 11.8 0.2 0.19 11.0 0.1 1.4 1 0 0 1 1 1 0 Transcription termination and cleavage factor C-terminal CGGC PF08821.6 AIN98945.1 - 0.11 12.6 0.0 0.2 11.7 0.0 1.4 1 0 0 1 1 1 0 CGGC domain Cyclin_N PF00134.18 AIN98946.1 - 1.3e-06 28.0 1.2 0.00091 18.8 0.0 3.1 3 0 0 3 3 3 2 Cyclin, N-terminal domain Prefoldin_2 PF01920.15 AIN98947.1 - 1.5e-11 43.9 1.2 1.9e-11 43.6 0.9 1.1 1 0 0 1 1 1 1 Prefoldin subunit Prefoldin PF02996.12 AIN98947.1 - 3.2e-05 23.5 1.9 0.0076 15.8 0.3 2.2 2 0 0 2 2 2 2 Prefoldin subunit HR1 PF02185.11 AIN98947.1 - 0.0038 16.9 0.9 1.9 8.2 0.3 2.2 2 0 0 2 2 2 2 Hr1 repeat AAA_13 PF13166.1 AIN98947.1 - 0.013 13.9 0.3 0.017 13.6 0.2 1.0 1 0 0 1 1 1 0 AAA domain Tropomyosin_1 PF12718.2 AIN98947.1 - 0.022 14.5 3.2 3.2 7.5 0.0 2.1 2 0 0 2 2 2 0 Tropomyosin like DUF4140 PF13600.1 AIN98947.1 - 0.022 15.1 1.1 6.3 7.2 0.2 2.2 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) DUF342 PF03961.8 AIN98947.1 - 0.046 12.1 0.3 0.057 11.8 0.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF342) DUF3166 PF11365.3 AIN98947.1 - 0.064 13.7 0.7 0.56 10.7 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3166) Ead_Ea22 PF13935.1 AIN98947.1 - 0.073 13.4 2.6 0.093 13.0 1.8 1.3 1 1 0 1 1 1 0 Ead/Ea22-like protein TPR_MLP1_2 PF07926.7 AIN98947.1 - 0.076 12.7 1.8 0.4 10.4 0.4 2.0 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein LigB PF02900.13 AIN98947.1 - 0.076 11.9 0.0 0.079 11.9 0.0 1.1 1 0 0 1 1 1 0 Catalytic LigB subunit of aromatic ring-opening dioxygenase DivIC PF04977.10 AIN98947.1 - 0.11 12.0 2.9 5.6 6.5 0.8 2.2 2 0 0 2 2 2 0 Septum formation initiator Spc24 PF08286.6 AIN98947.1 - 0.13 11.9 1.3 0.48 10.1 0.2 2.0 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 Seryl_tRNA_N PF02403.17 AIN98947.1 - 0.18 11.8 1.9 4.1 7.4 0.5 2.1 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain DUF2681 PF10883.3 AIN98947.1 - 0.23 11.6 1.2 6.5 7.0 0.3 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2681) KfrA_N PF11740.3 AIN98947.1 - 0.23 11.9 2.8 0.21 12.0 0.7 1.7 2 0 0 2 2 2 0 Plasmid replication region DNA-binding N-term IncA PF04156.9 AIN98947.1 - 0.34 10.4 5.4 4.1 6.9 3.9 1.9 1 1 0 1 1 1 0 IncA protein DUF4164 PF13747.1 AIN98947.1 - 1.4 9.0 6.9 12 6.1 4.8 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4164) DUF4526 PF15029.1 AIN98948.1 - 0.039 13.5 1.0 0.11 12.0 0.7 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF4526) PH PF00169.24 AIN98949.1 - 0.065 13.4 0.1 0.31 11.2 0.0 2.2 2 1 0 2 2 2 0 PH domain Cortex-I_coil PF09304.5 AIN98950.1 - 0.0098 15.9 9.1 0.023 14.7 6.3 1.5 1 0 0 1 1 1 1 Cortexillin I, coiled coil Kdo PF06293.9 AIN98952.1 - 1e-06 28.0 0.0 0.0008 18.5 0.0 2.2 2 0 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 AIN98952.1 - 0.00029 20.2 0.0 0.65 9.3 0.0 2.2 1 1 1 2 2 2 2 RIO1 family Pkinase PF00069.20 AIN98952.1 - 0.0026 16.9 0.0 0.061 12.4 0.0 2.0 2 0 0 2 2 2 1 Protein kinase domain APH PF01636.18 AIN98952.1 - 0.0047 16.6 0.2 0.057 13.1 0.1 2.3 1 1 0 1 1 1 1 Phosphotransferase enzyme family LRR_8 PF13855.1 AIN98953.1 - 1.6e-17 62.9 2.9 1e-10 41.2 1.6 3.6 2 1 1 3 3 3 2 Leucine rich repeat LRR_4 PF12799.2 AIN98953.1 - 3.9e-12 45.5 4.7 2.6e-07 30.1 0.1 3.9 4 0 0 4 4 4 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 AIN98953.1 - 1.5e-06 27.4 5.1 0.074 13.1 0.1 5.5 5 0 0 5 5 5 2 Leucine Rich Repeat LRR_6 PF13516.1 AIN98953.1 - 7.4e-05 22.4 0.9 1.8 8.8 0.0 4.3 3 0 0 3 3 3 2 Leucine Rich repeat LRR_9 PF14580.1 AIN98953.1 - 0.00021 20.9 0.0 0.00049 19.6 0.0 1.5 1 0 0 1 1 1 1 Leucine-rich repeat LRR_7 PF13504.1 AIN98953.1 - 0.0034 17.3 5.5 2.8 8.5 0.2 5.0 5 0 0 5 5 5 2 Leucine rich repeat Ribosomal_L23 PF00276.15 AIN98954.1 - 0.00015 21.5 0.4 0.00027 20.8 0.3 1.4 1 0 0 1 1 1 1 Ribosomal protein L23 Pro_isomerase PF00160.16 AIN98955.1 - 3.3e-43 147.5 0.0 3.7e-43 147.4 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD SLBP_RNA_bind PF15247.1 AIN98956.1 - 9.9e-14 50.8 0.3 9.9e-14 50.8 0.2 2.3 3 0 0 3 3 3 1 Histone RNA hairpin-binding protein RNA-binding domain Ank_4 PF13637.1 AIN98957.1 - 8.5e-22 77.1 1.2 1.9e-10 40.9 0.0 2.5 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.25 AIN98957.1 - 1.2e-20 72.1 6.5 1.1e-06 28.1 0.0 4.4 4 0 0 4 4 4 4 Ankyrin repeat Ank_2 PF12796.2 AIN98957.1 - 2.8e-19 69.2 0.1 3.1e-09 37.0 0.0 2.3 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.1 AIN98957.1 - 2.1e-17 62.7 6.6 9.1e-08 32.1 0.1 4.3 2 2 2 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 AIN98957.1 - 2.2e-15 55.2 1.9 0.00022 21.1 0.0 4.6 4 0 0 4 4 4 4 Ankyrin repeat zf-RVT PF13966.1 AIN98957.1 - 0.0048 17.1 0.0 0.011 15.9 0.0 1.7 1 1 0 1 1 1 1 zinc-binding in reverse transcriptase DUF3322 PF11795.3 AIN98958.1 - 0.0038 16.8 0.1 0.0094 15.6 0.1 1.6 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria N-term (DUF3322) PUB PF09409.5 AIN98959.1 - 0.011 15.4 0.0 0.021 14.5 0.0 1.4 1 0 0 1 1 1 0 PUB domain PcfJ PF14284.1 AIN98959.1 - 0.057 12.9 0.0 0.13 11.7 0.0 1.5 1 0 0 1 1 1 0 PcfJ-like protein Tubulin PF00091.20 AIN98960.1 - 1.8e-72 243.6 0.0 2.6e-72 243.1 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 AIN98960.1 - 2.7e-44 150.2 0.2 2.7e-44 150.2 0.1 1.7 2 0 0 2 2 2 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.4 AIN98960.1 - 4.2e-06 26.8 0.0 1.5e-05 24.9 0.0 1.9 1 1 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_2 PF13809.1 AIN98960.1 - 0.033 13.1 0.0 0.049 12.5 0.0 1.2 1 0 0 1 1 1 0 Tubulin like EF-hand_7 PF13499.1 AIN98961.1 - 7.9e-05 22.7 0.0 0.043 13.9 0.0 3.6 4 0 0 4 4 4 1 EF-hand domain pair EF-hand_6 PF13405.1 AIN98961.1 - 0.032 14.1 0.0 6.8 6.8 0.0 3.1 4 0 0 4 4 4 0 EF-hand domain EF-hand_1 PF00036.27 AIN98961.1 - 0.12 11.7 0.0 0.65 9.4 0.0 2.2 3 0 0 3 3 3 0 EF hand EF-hand_8 PF13833.1 AIN98961.1 - 0.37 10.4 0.0 2.5 7.8 0.0 2.4 3 0 0 3 3 3 0 EF-hand domain pair Dynein_heavy PF03028.10 AIN98962.1 - 7.7e-173 576.2 0.0 7.7e-173 576.2 0.0 2.8 3 0 0 3 3 3 1 Dynein heavy chain and region D6 of dynein motor DHC_N1 PF08385.7 AIN98962.1 - 7.9e-127 424.0 11.4 7.9e-127 424.0 7.9 3.7 3 0 0 3 3 3 2 Dynein heavy chain, N-terminal region 1 DHC_N2 PF08393.8 AIN98962.1 - 1.3e-117 392.8 2.1 1.3e-117 392.8 1.5 3.9 4 0 0 4 4 4 1 Dynein heavy chain, N-terminal region 2 AAA_6 PF12774.2 AIN98962.1 - 8e-92 306.9 0.0 2e-91 305.6 0.0 1.7 1 0 0 1 1 1 1 Hydrolytic ATP binding site of dynein motor region D1 AAA_8 PF12780.2 AIN98962.1 - 7e-72 241.5 0.0 1.4e-71 240.6 0.0 1.5 1 0 0 1 1 1 1 P-loop containing dynein motor region D4 AAA_9 PF12781.2 AIN98962.1 - 1.2e-54 184.5 1.7 3.4e-54 183.1 1.2 1.8 1 0 0 1 1 1 1 ATP-binding dynein motor region D5 AAA_7 PF12775.2 AIN98962.1 - 1.4e-41 142.3 0.0 3.6e-41 141.0 0.0 1.6 1 0 0 1 1 1 1 P-loop containing dynein motor region D3 MT PF12777.2 AIN98962.1 - 2.7e-37 128.3 8.6 2.7e-37 128.3 6.0 1.7 2 0 0 2 2 2 1 Microtubule-binding stalk of dynein motor AAA_5 PF07728.9 AIN98962.1 - 4.5e-15 55.6 0.0 0.002 17.8 0.0 5.6 4 1 0 4 4 4 3 AAA domain (dynein-related subfamily) AAA PF00004.24 AIN98962.1 - 1.5e-07 31.6 1.1 0.026 14.7 0.0 5.6 5 0 0 5 5 5 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 AIN98962.1 - 6.1e-07 29.6 0.4 1.2 9.1 0.0 5.6 4 0 0 4 4 4 2 AAA ATPase domain AAA_17 PF13207.1 AIN98962.1 - 0.0028 18.4 0.0 0.16 12.7 0.0 3.9 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 AIN98962.1 - 0.1 12.7 7.0 7 6.8 0.0 5.6 7 0 0 7 7 5 0 AAA domain Complex1_LYR PF05347.10 AIN98963.1 - 6.3e-05 22.6 0.1 0.00012 21.7 0.1 1.5 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 AIN98963.1 - 0.0016 18.6 0.1 0.0037 17.4 0.1 1.7 2 0 0 2 2 2 1 Complex1_LYR-like 2OG-FeII_Oxy PF03171.15 AIN98965.1 - 2.1e-11 43.9 0.0 4.8e-11 42.8 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.1 AIN98965.1 - 0.012 16.1 0.0 1.1 9.8 0.0 2.5 2 0 0 2 2 2 0 non-haem dioxygenase in morphine synthesis N-terminal SecE PF00584.15 AIN98966.1 - 2.1e-13 49.5 0.2 2.5e-13 49.3 0.2 1.1 1 0 0 1 1 1 1 SecE/Sec61-gamma subunits of protein translocation complex CobD_Cbib PF03186.8 AIN98966.1 - 0.018 14.1 0.0 0.02 13.9 0.0 1.0 1 0 0 1 1 1 0 CobD/Cbib protein NAD_binding_2 PF03446.10 AIN98967.1 - 8.2e-31 107.0 0.0 1.3e-30 106.3 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.1 AIN98967.1 - 1.6e-12 47.5 0.2 1.9e-11 44.0 0.0 2.5 2 0 0 2 2 2 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase Minor_capsid_1 PF10665.4 AIN98967.1 - 0.002 17.9 0.0 0.004 16.9 0.0 1.4 1 0 0 1 1 1 1 Minor capsid protein F420_oxidored PF03807.12 AIN98967.1 - 0.0022 18.4 0.1 0.014 15.8 0.0 2.2 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent GFO_IDH_MocA PF01408.17 AIN98967.1 - 0.01 16.3 0.0 0.87 10.1 0.0 2.8 2 1 0 2 2 2 0 Oxidoreductase family, NAD-binding Rossmann fold 3HCDH_N PF02737.13 AIN98967.1 - 0.023 14.3 0.0 0.045 13.4 0.0 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain IncA PF04156.9 AIN98969.1 - 0.0038 16.8 6.6 0.043 13.4 0.0 2.4 2 0 0 2 2 2 1 IncA protein Frataxin_Cyay PF01491.11 AIN98970.1 - 4.8e-28 97.1 0.0 8.6e-28 96.3 0.0 1.4 2 0 0 2 2 2 1 Frataxin-like domain RRM_5 PF13893.1 AIN98974.1 - 0.00022 21.0 0.0 0.00044 20.0 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 AIN98974.1 - 0.00077 19.3 0.1 0.0021 18.0 0.0 1.8 1 1 1 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 AIN98974.1 - 0.00095 18.7 0.1 0.002 17.7 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF2652 PF10851.3 AIN98974.1 - 0.0072 16.3 0.0 0.012 15.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2652) CorA PF01544.13 AIN98975.1 - 5.1e-19 68.4 0.1 2e-18 66.4 0.0 1.8 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein CTDII PF01556.13 AIN98976.1 - 2.2e-23 81.9 0.0 6.2e-23 80.4 0.0 1.8 2 0 0 2 2 2 1 DnaJ C terminal domain DnaJ PF00226.26 AIN98976.1 - 1.7e-16 59.6 0.1 2.9e-16 58.9 0.1 1.4 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.14 AIN98976.1 - 7e-15 54.8 12.9 1.1e-14 54.2 8.9 1.3 1 0 0 1 1 1 1 DnaJ central domain HypA PF01155.14 AIN98976.1 - 0.0083 15.8 4.8 0.28 10.8 0.3 2.3 2 0 0 2 2 2 2 Hydrogenase expression/synthesis hypA family DZR PF12773.2 AIN98976.1 - 0.054 13.3 11.3 5.2 6.9 8.3 2.3 1 1 1 2 2 2 0 Double zinc ribbon DUF879 PF05947.7 AIN98976.1 - 0.088 11.1 0.0 0.13 10.6 0.0 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF879) DNA_ligase_ZBD PF03119.11 AIN98976.1 - 0.25 11.0 0.2 0.25 11.0 0.1 2.8 3 0 0 3 3 3 0 NAD-dependent DNA ligase C4 zinc finger domain zf-RING_3 PF14369.1 AIN98976.1 - 0.28 11.1 11.9 3 7.9 0.6 3.5 2 1 1 3 3 3 0 zinc-finger Integrase_Zn PF02022.14 AIN98976.1 - 0.29 10.6 4.6 5.2 6.5 0.5 2.7 2 0 0 2 2 2 0 Integrase Zinc binding domain Terminase_GpA PF05876.7 AIN98976.1 - 0.76 8.0 4.7 1.6 6.9 3.3 1.5 1 0 0 1 1 1 0 Phage terminase large subunit (GpA) Prok-RING_1 PF14446.1 AIN98976.1 - 0.82 9.4 10.1 0.42 10.3 0.9 2.6 2 1 1 3 3 3 0 Prokaryotic RING finger family 1 zf-ribbon_3 PF13248.1 AIN98976.1 - 1.7 7.9 6.7 20 4.5 0.1 3.4 3 0 0 3 3 3 0 zinc-ribbon domain DUF1272 PF06906.6 AIN98976.1 - 3.2 7.6 10.4 18 5.2 2.6 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF1272) UPF0547 PF10571.4 AIN98976.1 - 3.3 7.5 9.8 19 5.0 0.4 3.5 3 0 0 3 3 3 0 Uncharacterised protein family UPF0547 OrfB_Zn_ribbon PF07282.6 AIN98976.1 - 3.5 7.3 7.8 14 5.3 1.3 2.5 2 0 0 2 2 2 0 Putative transposase DNA-binding domain Ogr_Delta PF04606.7 AIN98976.1 - 4 7.1 10.2 21 4.8 0.0 3.4 3 0 0 3 3 3 0 Ogr/Delta-like zinc finger zf-Mss51 PF13824.1 AIN98976.1 - 4.2 7.3 9.1 1.2 9.0 2.5 2.4 2 0 0 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 Cys_rich_KTR PF14205.1 AIN98976.1 - 6.2 6.3 7.2 38 3.8 0.4 3.2 2 1 1 3 3 3 0 Cysteine-rich KTR zf-FPG_IleRS PF06827.9 AIN98976.1 - 7.6 6.2 10.4 39 4.0 0.1 3.6 3 1 0 3 3 3 0 Zinc finger found in FPG and IleRS Lar_restr_allev PF14354.1 AIN98976.1 - 9.2 6.6 13.4 3.3e+02 1.6 7.2 3.6 1 1 0 1 1 1 0 Restriction alleviation protein Lar Zn-ribbon_8 PF09723.5 AIN98976.1 - 9.6 6.2 16.4 13 5.7 2.0 3.7 2 2 2 4 4 4 0 Zinc ribbon domain Kelch_6 PF13964.1 AIN98977.1 - 0.00017 21.6 0.1 0.48 10.6 0.0 3.5 3 0 0 3 3 3 2 Kelch motif Kelch_1 PF01344.20 AIN98977.1 - 0.00036 20.0 0.0 0.82 9.2 0.0 3.0 2 0 0 2 2 2 2 Kelch motif Aldedh PF00171.17 AIN98978.1 - 9.2e-180 597.8 0.6 1e-179 597.7 0.4 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 AIN98978.1 - 0.003 16.3 0.0 0.0055 15.4 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA reductase (LuxC) DUF1487 PF07368.6 AIN98978.1 - 0.1 11.8 0.0 0.21 10.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1487) SBP_bac_3 PF00497.15 AIN98979.1 - 0.014 14.6 0.0 2.3 7.4 0.0 2.0 2 0 0 2 2 2 0 Bacterial extracellular solute-binding proteins, family 3 Mec-17 PF05301.6 AIN98981.1 - 1.9e-32 111.7 0.1 2.8e-32 111.1 0.0 1.2 1 0 0 1 1 1 1 Touch receptor neuron protein Mec-17 Acetyltransf_1 PF00583.19 AIN98981.1 - 0.00023 21.1 0.0 0.001 19.0 0.0 2.0 1 1 1 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 AIN98981.1 - 0.016 15.3 0.0 0.034 14.3 0.0 1.7 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain LMBR1 PF04791.11 AIN98982.1 - 7e-30 104.0 32.2 3.3e-17 62.2 7.6 2.1 1 1 0 2 2 2 2 LMBR1-like membrane protein DUF3188 PF11384.3 AIN98982.1 - 0.066 12.8 4.1 0.067 12.7 0.5 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3188) ATP-synt_ab PF00006.20 AIN98983.1 - 1.3e-64 217.6 0.1 1.1e-63 214.5 0.0 2.1 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 AIN98983.1 - 6.8e-22 78.0 0.3 1.2e-21 77.3 0.2 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 AIN98983.1 - 5.4e-14 52.1 0.2 1.3e-13 50.9 0.2 1.7 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain AAA_25 PF13481.1 AIN98983.1 - 0.0015 17.9 1.0 0.0059 16.0 0.0 2.2 2 1 0 2 2 2 1 AAA domain AAA PF00004.24 AIN98983.1 - 0.0042 17.2 0.1 0.029 14.5 0.0 2.2 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) KaiC PF06745.8 AIN98983.1 - 0.0047 16.0 0.1 0.0083 15.2 0.0 1.4 1 0 0 1 1 1 1 KaiC DUF258 PF03193.11 AIN98983.1 - 0.054 12.6 0.1 0.095 11.8 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 Ribosomal_S25 PF03297.10 AIN98984.1 - 1.8e-42 143.6 3.7 2.1e-42 143.4 2.5 1.0 1 0 0 1 1 1 1 S25 ribosomal protein Mnd1 PF03962.10 AIN98984.1 - 0.073 12.7 0.4 0.09 12.4 0.3 1.2 1 0 0 1 1 1 0 Mnd1 family DNA_methylase PF00145.12 AIN98985.1 - 2.5e-39 135.3 0.0 3.1e-30 105.4 0.0 3.6 2 1 0 2 2 2 2 C-5 cytosine-specific DNA methylase WD40 PF00400.27 AIN98986.1 - 3.9e-05 23.3 0.1 0.073 12.9 0.0 4.6 3 1 0 3 3 3 2 WD domain, G-beta repeat PPR_3 PF13812.1 AIN98988.1 - 1.3 9.5 9.6 37 4.9 0.0 6.9 8 0 0 8 8 8 0 Pentatricopeptide repeat domain zf-RING_2 PF13639.1 AIN98989.1 - 0.0023 17.7 8.3 0.011 15.5 5.7 2.3 1 0 0 1 1 1 1 Ring finger domain IncA PF04156.9 AIN98991.1 - 0.058 12.9 0.6 0.11 12.0 0.4 1.4 1 0 0 1 1 1 0 IncA protein Striatin PF08232.7 AIN98991.1 - 0.082 13.2 0.1 0.24 11.7 0.0 1.8 2 0 0 2 2 2 0 Striatin family HeH PF12949.2 AIN98991.1 - 0.16 11.5 0.4 0.74 9.4 0.0 2.1 2 0 0 2 2 2 0 HeH/LEM domain Cullin PF00888.17 AIN98992.1 - 1.9e-39 135.6 0.0 2.8e-38 131.8 0.0 2.2 2 1 0 2 2 2 1 Cullin family Cullin_Nedd8 PF10557.4 AIN98992.1 - 5.8e-13 48.4 0.0 1.6e-12 47.0 0.0 1.8 1 0 0 1 1 1 1 Cullin protein neddylation domain NPL4 PF05021.10 AIN98993.1 - 4.8e-21 75.2 0.0 2.2e-20 73.0 0.0 2.0 1 1 0 1 1 1 1 NPL4 family PRP38 PF03371.10 AIN98994.1 - 5.3e-05 22.9 0.0 8.7e-05 22.2 0.0 1.3 1 0 0 1 1 1 1 PRP38 family MbeB_N PF04837.7 AIN98994.1 - 0.12 12.5 0.0 0.68 10.0 0.0 2.2 2 0 0 2 2 2 0 MbeB-like, N-term conserved region PPP4R2 PF09184.6 AIN98995.1 - 0.0015 18.1 0.0 0.0025 17.4 0.0 1.4 1 0 0 1 1 1 1 PPP4R2 RNA_pol_N PF01194.12 AIN98996.1 - 7.7e-29 99.5 0.8 9.3e-29 99.2 0.6 1.1 1 0 0 1 1 1 1 RNA polymerases N / 8 kDa subunit Yippee-Mis18 PF03226.9 AIN98996.1 - 0.079 13.0 0.4 0.1 12.6 0.3 1.3 1 1 0 1 1 1 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly Chordopox_RPO7 PF05864.7 AIN98996.1 - 0.12 12.4 0.3 0.15 12.1 0.2 1.2 1 0 0 1 1 1 0 Chordopoxvirus DNA-directed RNA polymerase 7 kDa polypeptide (RPO7) Metallophos PF00149.23 AIN98997.1 - 1.8e-41 141.7 1.6 2.5e-41 141.3 1.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Ribonuclease_3 PF00636.21 AIN98998.1 - 0.046 14.1 0.1 0.43 11.0 0.0 2.5 2 1 0 2 2 2 0 Ribonuclease III domain GIY-YIG PF01541.19 AIN98999.1 - 4.9e-07 30.0 0.0 9e-07 29.1 0.0 1.4 1 0 0 1 1 1 1 GIY-YIG catalytic domain T5orf172 PF10544.4 AIN98999.1 - 0.064 13.6 0.1 0.17 12.3 0.0 1.7 2 0 0 2 2 2 0 T5orf172 domain DUF329 PF03884.9 AIN98999.1 - 3.2 7.3 6.4 0.36 10.4 0.5 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF329) Sec23_trunk PF04811.10 AIN99000.1 - 1.2e-37 129.5 0.0 2.2e-37 128.7 0.0 1.4 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_BS PF08033.7 AIN99000.1 - 6e-17 61.9 0.2 1.1e-16 61.0 0.2 1.5 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain Sec23_helical PF04815.10 AIN99000.1 - 2e-16 59.2 0.0 3.4e-16 58.5 0.0 1.4 1 0 0 1 1 1 1 Sec23/Sec24 helical domain zf-Sec23_Sec24 PF04810.10 AIN99000.1 - 7.3e-15 54.2 1.0 1.8e-14 52.9 0.7 1.8 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger DUF1034 PF06280.7 AIN99001.1 - 0.021 15.1 1.7 0.57 10.6 0.0 4.2 5 0 0 5 5 5 0 Fn3-like domain (DUF1034) HTH_9 PF08221.6 AIN99002.1 - 0.19 11.6 0.1 0.54 10.1 0.1 1.7 1 0 0 1 1 1 0 RNA polymerase III subunit RPC82 helix-turn-helix domain TAP42 PF04177.7 AIN99003.1 - 1.4e-29 103.0 4.7 6.5e-18 64.7 4.4 2.2 2 0 0 2 2 2 2 TAP42-like family ATP_bind_1 PF03029.12 AIN99005.1 - 4.3e-49 167.1 0.0 4.9e-49 167.0 0.0 1.0 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein Surp PF01805.15 AIN99006.1 - 2.2e-11 43.2 0.7 1.1e-07 31.3 0.0 2.3 2 0 0 2 2 2 2 Surp module OHCU_decarbox PF09349.5 AIN99006.1 - 0.26 11.5 2.2 0.75 10.0 0.1 2.6 2 1 1 3 3 3 0 OHCU decarboxylase DNA_pol_E_B PF04042.11 AIN99007.1 - 1.3e-27 96.3 1.1 4.1e-25 88.2 0.7 2.2 1 1 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B Ras PF00071.17 AIN99008.1 - 1.5e-50 170.7 0.0 1.9e-50 170.4 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 AIN99008.1 - 6.5e-17 62.1 0.0 1.2e-16 61.2 0.0 1.5 2 0 0 2 2 1 1 Miro-like protein Arf PF00025.16 AIN99008.1 - 4.3e-11 42.3 0.0 5.7e-11 41.9 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family RNA_helicase PF00910.17 AIN99008.1 - 0.00027 21.0 0.2 0.0017 18.4 0.1 2.0 1 1 0 1 1 1 1 RNA helicase Gtr1_RagA PF04670.7 AIN99008.1 - 0.00038 19.6 0.0 0.00046 19.3 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region cobW PF02492.14 AIN99008.1 - 0.015 14.7 0.1 2.6 7.4 0.0 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain G-alpha PF00503.15 AIN99008.1 - 0.029 13.0 1.7 1.1 7.8 0.1 2.9 2 1 1 3 3 3 0 G-protein alpha subunit AAA_22 PF13401.1 AIN99008.1 - 0.03 14.4 0.1 0.28 11.3 0.0 2.3 3 0 0 3 3 3 0 AAA domain GTP_EFTU PF00009.22 AIN99008.1 - 0.037 13.4 0.7 0.33 10.3 0.5 2.1 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain AAA_33 PF13671.1 AIN99008.1 - 0.037 13.8 0.0 0.056 13.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain Pox_A32 PF04665.7 AIN99008.1 - 0.073 12.3 0.0 0.13 11.5 0.0 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein Septin PF00735.13 AIN99008.1 - 0.12 11.3 0.0 0.2 10.6 0.0 1.3 1 0 0 1 1 1 0 Septin ATP_bind_1 PF03029.12 AIN99008.1 - 0.13 11.7 0.4 11 5.4 0.0 2.2 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein PduV-EutP PF10662.4 AIN99008.1 - 0.14 11.6 0.0 1.1 8.7 0.0 2.1 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Cluap1 PF10234.4 AIN99009.1 - 9.4e-103 343.0 13.4 1.3e-102 342.6 9.3 1.1 1 0 0 1 1 1 1 Clusterin-associated protein-1 Lectin_N PF03954.9 AIN99009.1 - 0.053 12.9 0.4 0.17 11.2 0.3 1.8 1 0 0 1 1 1 0 Hepatic lectin, N-terminal domain RNase_T PF00929.19 AIN99010.1 - 1.5e-05 25.3 0.0 2.7e-05 24.5 0.0 1.4 1 0 0 1 1 1 1 Exonuclease DUF1295 PF06966.7 AIN99012.1 - 4.3e-09 36.0 1.5 6.3e-09 35.4 0.3 1.8 1 1 1 2 2 2 1 Protein of unknown function (DUF1295) PEMT PF04191.8 AIN99012.1 - 1.6e-05 24.9 0.9 4.6e-05 23.4 0.7 1.8 1 0 0 1 1 1 1 Phospholipid methyltransferase Steroid_dh PF02544.11 AIN99012.1 - 0.0028 17.4 1.8 0.0031 17.3 0.4 1.7 1 1 1 2 2 2 1 3-oxo-5-alpha-steroid 4-dehydrogenase ICMT PF04140.9 AIN99012.1 - 0.055 13.6 0.9 0.12 12.5 0.0 2.1 3 0 0 3 3 3 0 Isoprenylcysteine carboxyl methyltransferase (ICMT) family RF-1 PF00472.15 AIN99013.1 - 3.6e-31 107.3 0.0 7.1e-31 106.3 0.0 1.5 1 0 0 1 1 1 1 RF-1 domain PCRF PF03462.13 AIN99013.1 - 7.7e-14 51.3 0.4 1.7e-13 50.2 0.3 1.6 1 0 0 1 1 1 1 PCRF domain DUF1126 PF06565.7 AIN99014.1 - 3.8e-31 106.2 0.0 4.8e-09 35.5 0.0 4.0 3 0 0 3 3 3 3 Repeat of unknown function (DUF1126) EF-hand_7 PF13499.1 AIN99014.1 - 0.019 15.0 0.4 1.1 9.4 0.0 3.0 2 0 0 2 2 2 0 EF-hand domain pair Cyclin_N PF00134.18 AIN99015.1 - 8.9e-37 125.4 0.3 1.8e-36 124.5 0.2 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 AIN99015.1 - 1.6e-13 50.6 0.1 3.2e-13 49.6 0.0 1.6 2 0 0 2 2 2 1 Cyclin, C-terminal domain NfI_DNAbd_pre-N PF10524.4 AIN99015.1 - 0.038 13.5 0.0 0.089 12.4 0.0 1.6 1 0 0 1 1 1 0 Nuclear factor I protein pre-N-terminus Rhodopsin_N PF10413.4 AIN99015.1 - 0.047 13.3 0.0 0.11 12.2 0.0 1.5 1 0 0 1 1 1 0 Amino terminal of the G-protein receptor rhodopsin Peptidase_C2 PF00648.16 AIN99017.1 - 1.4e-50 171.9 0.2 2.6e-50 171.0 0.2 1.5 1 0 0 1 1 1 1 Calpain family cysteine protease DUF1935 PF09149.5 AIN99017.1 - 1.2e-25 89.5 0.2 3e-25 88.1 0.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1935) M60-like PF13402.1 AIN99017.1 - 0.0052 15.7 0.0 0.01 14.7 0.0 1.5 1 0 0 1 1 1 1 Peptidase M60-like family Leader_Trp PF08255.6 AIN99017.1 - 4.4 7.1 6.5 53 3.8 1.5 3.8 3 0 0 3 3 3 0 Trp-operon Leader Peptide Rab3-GTPase_cat PF13890.1 AIN99018.1 - 1.4e-48 164.3 0.1 2.6e-48 163.5 0.1 1.5 1 0 0 1 1 1 1 Rab3 GTPase-activating protein catalytic subunit Nol1_Nop2_Fmu PF01189.12 AIN99019.1 - 3e-18 66.2 0.0 6.8e-13 48.6 0.0 2.2 2 0 0 2 2 2 2 NOL1/NOP2/sun family PUA PF01472.15 AIN99019.1 - 1.8e-06 27.5 0.2 3.2e-06 26.7 0.1 1.4 1 0 0 1 1 1 1 PUA domain vMSA PF00695.14 AIN99019.1 - 0.047 12.9 1.7 0.67 9.0 0.3 2.2 2 0 0 2 2 2 0 Major surface antigen from hepadnavirus Acyl-CoA_dh_C PF12806.2 AIN99020.1 - 0.17 11.7 2.9 0.41 10.5 2.0 1.6 1 0 0 1 1 1 0 Acetyl-CoA dehydrogenase C-terminal like Pkinase PF00069.20 AIN99021.1 - 1.5e-44 152.1 0.0 2e-44 151.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AIN99021.1 - 2.8e-30 105.2 0.0 4.1e-30 104.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 AIN99021.1 - 4.2e-05 22.6 0.0 6.6e-05 21.9 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 AIN99021.1 - 0.02 14.6 1.6 0.13 11.9 0.0 2.6 2 1 1 3 3 3 0 Phosphotransferase enzyme family ABC_ATPase PF09818.4 AIN99023.1 - 2.7e-165 550.3 0.0 3.4e-165 549.9 0.0 1.1 1 0 0 1 1 1 1 Predicted ATPase of the ABC class AAA_23 PF13476.1 AIN99023.1 - 0.046 14.0 0.0 0.072 13.4 0.0 1.2 1 0 0 1 1 1 0 AAA domain zf-Tim10_DDP PF02953.10 AIN99024.1 - 3.2e-05 23.1 0.3 5e-05 22.5 0.2 1.4 1 1 0 1 1 1 1 Tim10/DDP family zinc finger Pkinase PF00069.20 AIN99025.1 - 2.1e-28 99.2 0.0 3.5e-15 55.8 0.0 3.9 3 1 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.12 AIN99025.1 - 3e-06 26.4 0.0 0.83 8.6 0.0 3.2 3 0 0 3 3 3 3 Protein tyrosine kinase Pox_ser-thr_kin PF05445.6 AIN99025.1 - 0.3 9.8 0.1 0.46 9.2 0.1 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Macoilin PF09726.4 AIN99025.1 - 0.33 9.1 6.5 0.54 8.4 4.5 1.2 1 0 0 1 1 1 0 Transmembrane protein TRAPPC-Trs85 PF12739.2 AIN99026.1 - 2.6e-32 111.9 0.5 4.9e-32 111.1 0.4 1.4 1 0 0 1 1 1 1 ER-Golgi trafficking TRAPP I complex 85 kDa subunit TPR_11 PF13414.1 AIN99026.1 - 0.0018 17.9 1.1 0.0078 15.8 0.1 2.4 2 0 0 2 2 2 1 TPR repeat TPR_1 PF00515.23 AIN99026.1 - 0.36 10.5 1.0 2 8.1 0.3 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.1 AIN99026.1 - 1.8 8.5 10.8 0.15 12.0 0.4 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat Pkinase PF00069.20 AIN99027.1 - 3.8e-33 114.7 0.1 3.3e-31 108.3 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AIN99027.1 - 1.6e-12 47.0 0.0 4.7e-08 32.4 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.18 AIN99027.1 - 0.052 13.2 0.1 0.17 11.5 0.0 1.9 2 0 0 2 2 2 0 Phosphotransferase enzyme family Kinase-like PF14531.1 AIN99027.1 - 0.096 11.6 0.0 0.17 10.8 0.0 1.3 1 0 0 1 1 1 0 Kinase-like BRCT PF00533.21 AIN99028.1 - 0.0011 19.0 0.0 0.079 13.1 0.0 3.3 3 0 0 3 3 3 1 BRCA1 C Terminus (BRCT) domain WD40 PF00400.27 AIN99029.1 - 5.8e-19 67.1 11.1 0.082 12.8 0.0 9.5 10 0 0 10 10 10 7 WD domain, G-beta repeat JAB PF01398.16 AIN99030.1 - 0.00033 20.3 0.1 0.00086 19.0 0.0 1.8 2 0 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease DUF2150 PF09920.4 AIN99030.1 - 0.049 13.2 0.1 0.074 12.6 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2150) DAGAT PF03982.8 AIN99032.1 - 2e-73 246.7 0.0 2.5e-73 246.3 0.0 1.1 1 0 0 1 1 1 1 Diacylglycerol acyltransferase KOW PF00467.24 AIN99033.1 - 0.042 13.5 1.2 0.11 12.2 0.9 1.7 1 0 0 1 1 1 0 KOW motif DUF1016 PF06250.6 AIN99033.1 - 0.043 12.7 0.1 0.085 11.8 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1016) CHCH PF06747.8 AIN99034.1 - 0.0027 17.5 5.0 0.086 12.7 0.4 2.4 2 0 0 2 2 2 2 CHCH domain COX6B PF02297.12 AIN99034.1 - 0.12 12.4 2.6 0.46 10.5 1.7 1.8 1 1 0 1 1 1 0 Cytochrome oxidase c subunit VIb DUF3716 PF12511.3 AIN99034.1 - 0.29 10.7 2.3 0.32 10.6 1.1 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3716) EFP_N PF08207.7 AIN99035.1 - 2e-05 24.3 0.3 3.3e-05 23.6 0.2 1.3 1 0 0 1 1 1 1 Elongation factor P (EF-P) KOW-like domain HORMA PF02301.13 AIN99037.1 - 5.1e-36 124.1 0.0 5.9e-36 123.9 0.0 1.0 1 0 0 1 1 1 1 HORMA domain VWA_3 PF13768.1 AIN99037.1 - 0.073 12.7 0.0 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 von Willebrand factor type A domain TPR_12 PF13424.1 AIN99038.1 - 2.8e-15 55.9 23.0 2.9e-05 23.9 2.5 5.0 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_2 PF07719.12 AIN99038.1 - 1.2e-05 24.8 10.7 0.45 10.5 0.0 5.4 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_11 PF13414.1 AIN99038.1 - 0.00011 21.7 12.0 0.46 10.1 0.6 5.0 4 0 0 4 4 4 3 TPR repeat TPR_1 PF00515.23 AIN99038.1 - 1.4 8.6 8.2 43 3.9 0.4 4.5 4 0 0 4 4 4 0 Tetratricopeptide repeat DnaJ PF00226.26 AIN99039.1 - 7.6e-06 25.5 1.0 4.3e-05 23.1 0.7 2.2 1 1 0 1 1 1 1 DnaJ domain HSCB_C PF07743.8 AIN99039.1 - 0.0011 19.3 0.1 0.0036 17.7 0.0 2.0 3 0 0 3 3 3 1 HSCB C-terminal oligomerisation domain LRR_4 PF12799.2 AIN99040.1 - 9.4e-13 47.4 0.6 2e-06 27.3 0.2 2.6 1 1 2 3 3 3 3 Leucine Rich repeats (2 copies) LRR_9 PF14580.1 AIN99040.1 - 1.5e-10 40.8 0.0 2.9e-10 39.9 0.0 1.3 1 0 0 1 1 1 1 Leucine-rich repeat LRR_8 PF13855.1 AIN99040.1 - 6.3e-07 29.0 2.0 1.3e-06 28.0 1.4 1.5 1 0 0 1 1 1 1 Leucine rich repeat LRR_6 PF13516.1 AIN99040.1 - 0.00017 21.3 0.1 5.7 7.3 0.1 3.7 2 1 1 3 3 3 2 Leucine Rich repeat LRR_1 PF00560.28 AIN99040.1 - 0.00039 20.0 0.6 2.2 8.6 0.1 3.6 3 0 0 3 3 3 1 Leucine Rich Repeat LRR_7 PF13504.1 AIN99040.1 - 0.0026 17.6 1.5 15 6.3 0.4 3.8 3 0 0 3 3 3 1 Leucine rich repeat LSM PF01423.17 AIN99041.1 - 4e-14 51.9 0.0 5.4e-14 51.4 0.0 1.2 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 AIN99041.1 - 0.0079 16.1 0.4 0.015 15.2 0.3 1.7 1 1 0 1 1 1 1 Ataxin 2 SM domain Transket_pyr PF02779.19 AIN99042.1 - 6e-45 152.9 0.1 8.7e-45 152.3 0.0 1.2 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.15 AIN99042.1 - 2e-37 127.8 0.1 8.2e-37 125.8 0.0 2.0 2 0 0 2 2 2 1 Transketolase, C-terminal domain Mito_fiss_reg PF05308.6 AIN99044.1 - 7.7 5.8 10.2 0.65 9.3 3.9 1.5 2 0 0 2 2 2 0 Mitochondrial fission regulator DUF1935 PF09149.5 AIN99046.1 - 2.6e-26 91.6 0.0 3e-26 91.3 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1935) Steroid_dh PF02544.11 AIN99048.1 - 3.9e-25 88.3 3.7 6.6e-25 87.6 2.5 1.4 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase DUF1295 PF06966.7 AIN99048.1 - 2.3e-06 27.1 0.7 3.6e-06 26.4 0.5 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) FA_desaturase PF00487.19 AIN99048.1 - 0.026 13.9 2.6 0.036 13.4 1.8 1.3 1 0 0 1 1 1 0 Fatty acid desaturase PEMT PF04191.8 AIN99048.1 - 0.026 14.6 4.4 0.19 11.8 0.6 2.4 1 1 1 2 2 2 0 Phospholipid methyltransferase YukD PF08817.5 AIN99048.1 - 0.043 14.3 0.0 0.075 13.5 0.0 1.4 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukD ATP-grasp_4 PF13535.1 AIN99049.1 - 2.1e-15 56.9 0.0 5.2e-15 55.6 0.0 1.7 1 0 0 1 1 1 1 ATP-grasp domain Dala_Dala_lig_C PF07478.8 AIN99049.1 - 6.8e-14 51.7 0.0 1.4e-13 50.7 0.0 1.5 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus SET PF00856.23 AIN99049.1 - 1.3e-05 25.5 0.0 1.3e-05 25.5 0.0 2.9 3 1 0 3 3 3 1 SET domain RimK PF08443.6 AIN99049.1 - 2.4e-05 23.8 0.0 7.5e-05 22.2 0.0 1.8 2 0 0 2 2 2 1 RimK-like ATP-grasp domain ATP-grasp_3 PF02655.9 AIN99049.1 - 0.00033 20.5 0.0 0.0018 18.1 0.0 2.1 1 1 0 1 1 1 1 ATP-grasp domain ATP-grasp PF02222.17 AIN99049.1 - 0.0054 16.1 0.0 0.011 15.1 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain CHAP PF05257.11 AIN99050.1 - 1.6e-05 24.5 0.2 0.0031 17.1 0.0 2.4 2 0 0 2 2 2 2 CHAP domain Thioredoxin PF00085.15 AIN99052.1 - 0.0025 17.4 0.0 0.0042 16.7 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin SLBP_RNA_bind PF15247.1 AIN99054.1 - 1.8e-22 78.8 1.8 5.1e-22 77.4 1.3 1.7 1 0 0 1 1 1 1 Histone RNA hairpin-binding protein RNA-binding domain EPL1 PF10513.4 AIN99054.1 - 0.14 12.4 0.1 0.59 10.3 0.1 2.1 1 0 0 1 1 1 0 Enhancer of polycomb-like Not3 PF04065.10 AIN99055.1 - 1.7e-72 243.4 24.2 1.7e-72 243.4 16.8 1.9 2 0 0 2 2 2 1 Not1 N-terminal domain, CCR4-Not complex component NOT2_3_5 PF04153.13 AIN99055.1 - 4.9e-35 120.3 8.4 4.9e-35 120.3 5.9 2.7 3 0 0 3 3 3 1 NOT2 / NOT3 / NOT5 family Dishevelled PF02377.10 AIN99055.1 - 5.5 7.2 8.8 0.28 11.4 1.5 2.3 2 0 0 2 2 2 0 Dishevelled specific domain WD40 PF00400.27 AIN99056.1 - 7e-21 73.2 2.8 0.00039 20.1 0.0 6.3 6 1 0 6 6 6 5 WD domain, G-beta repeat TPM PF04536.9 AIN99057.1 - 1.3e-14 54.0 0.0 2e-14 53.4 0.0 1.3 1 0 0 1 1 1 1 TLP18.3, Psb32 and MOLO-1 founding proteins of phosphatase Thioredoxin_3 PF13192.1 AIN99057.1 - 0.72 9.7 4.1 22 4.9 0.3 3.7 4 1 0 4 4 4 0 Thioredoxin domain DUF2387 PF09526.5 AIN99057.1 - 2.5 8.0 9.1 9.5 6.2 3.8 2.7 2 0 0 2 2 2 0 Probable metal-binding protein (DUF2387) Erythro-docking PF09277.6 AIN99058.1 - 0.093 12.4 0.6 5.6 6.7 0.0 3.5 3 0 0 3 3 3 0 Erythronolide synthase, docking DUF883 PF05957.8 AIN99058.1 - 0.16 12.3 4.2 2 8.8 0.1 3.5 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF883) Vps55 PF04133.9 AIN99059.1 - 3.7e-30 104.1 1.7 4.2e-30 103.9 1.2 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting 55 MARVEL PF01284.18 AIN99059.1 - 1.2 8.9 6.5 1.2 8.9 1.5 2.1 2 0 0 2 2 2 0 Membrane-associating domain Ycf66_N PF07444.6 AIN99059.1 - 1.9 8.2 5.3 0.35 10.6 0.6 2.0 2 0 0 2 2 2 0 Ycf66 protein N-terminus DUF4131 PF13567.1 AIN99059.1 - 3.2 7.1 9.0 7.5 5.9 2.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) ABC2_membrane PF01061.19 AIN99059.1 - 6.7 5.8 8.7 5.7 6.0 1.7 2.1 2 0 0 2 2 2 0 ABC-2 type transporter DUF2372 PF10178.4 AIN99060.1 - 0.00082 19.4 0.0 0.0013 18.8 0.0 1.3 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2372) DFP PF04127.10 AIN99061.1 - 1.2e-20 73.9 0.0 5e-11 42.5 0.0 2.3 1 1 1 2 2 2 2 DNA / pantothenate metabolism flavoprotein DNA_repr_REX1B PF14966.1 AIN99062.1 - 0.016 15.5 3.4 0.22 11.9 0.2 2.7 3 0 0 3 3 3 0 DNA repair REX1-B CCDC144C PF14915.1 AIN99062.1 - 0.058 12.3 0.3 0.13 11.1 0.2 1.5 1 0 0 1 1 1 0 CCDC144C protein coiled-coil region TPR_12 PF13424.1 AIN99063.1 - 4.8e-12 45.6 26.5 7.1e-06 25.8 1.1 3.6 2 1 0 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.1 AIN99063.1 - 0.0018 17.8 17.1 0.26 10.9 0.4 4.0 3 2 0 3 3 3 2 TPR repeat TPR_7 PF13176.1 AIN99063.1 - 0.01 15.5 0.2 0.01 15.5 0.2 5.9 6 0 0 6 6 6 0 Tetratricopeptide repeat Tcf25 PF04910.9 AIN99063.1 - 0.015 14.2 0.7 0.024 13.5 0.5 1.2 1 0 0 1 1 1 0 Transcriptional repressor TCF25 Apc5 PF12862.2 AIN99063.1 - 0.05 13.4 11.4 1.6 8.6 1.4 3.6 2 2 0 2 2 2 0 Anaphase-promoting complex subunit 5 TPR_2 PF07719.12 AIN99063.1 - 0.05 13.5 26.1 0.72 9.9 0.1 6.7 6 1 0 6 6 6 0 Tetratricopeptide repeat TPR_14 PF13428.1 AIN99063.1 - 0.12 13.0 28.7 3.2 8.6 0.2 6.9 5 1 1 6 6 6 0 Tetratricopeptide repeat TPR_8 PF13181.1 AIN99063.1 - 0.22 11.3 9.5 4.5 7.2 0.1 4.8 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_1 PF00515.23 AIN99063.1 - 1.1 8.9 15.9 0.58 9.8 0.1 5.3 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_16 PF13432.1 AIN99063.1 - 2.4 8.9 32.3 0.8 10.4 6.5 4.2 4 1 1 5 5 5 0 Tetratricopeptide repeat RRM_1 PF00076.17 AIN99064.1 - 0.042 13.4 0.0 0.074 12.7 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Kinesin PF00225.18 AIN99066.1 - 5e-78 262.1 0.1 5e-78 262.1 0.1 1.9 2 0 0 2 2 2 1 Kinesin motor domain ResIII PF04851.10 AIN99066.1 - 0.092 12.5 0.1 0.26 11.0 0.1 1.7 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit DUF342 PF03961.8 AIN99066.1 - 0.11 10.9 9.0 0.0059 15.0 2.6 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF342) DUF445 PF04286.7 AIN99066.1 - 1.1 8.7 7.0 2.5 7.5 3.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF445) AAA_23 PF13476.1 AIN99066.1 - 3.5 7.9 7.1 5.1 7.3 1.2 2.4 2 0 0 2 2 2 0 AAA domain Acylphosphatase PF00708.13 AIN99067.1 - 6.2e-24 83.9 0.0 9e-24 83.3 0.0 1.2 1 0 0 1 1 1 1 Acylphosphatase Kinesin PF00225.18 AIN99068.1 - 5.5e-101 337.6 0.0 1.1e-100 336.6 0.0 1.5 1 0 0 1 1 1 1 Kinesin motor domain Fib_alpha PF08702.5 AIN99068.1 - 0.18 11.9 22.7 0.25 11.4 4.4 3.8 3 2 1 4 4 4 0 Fibrinogen alpha/beta chain family AAA_22 PF13401.1 AIN99068.1 - 0.36 10.9 0.0 0.36 10.9 0.0 3.6 3 1 0 3 3 3 0 AAA domain Pkinase PF00069.20 AIN99070.1 - 1.1e-56 191.9 0.0 5.1e-43 147.1 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 AIN99070.1 - 2.1e-32 112.2 0.0 6.1e-24 84.4 0.0 2.3 3 0 0 3 3 3 2 Protein tyrosine kinase Kinase-like PF14531.1 AIN99070.1 - 0.00029 19.9 0.0 0.031 13.2 0.0 2.5 3 0 0 3 3 3 1 Kinase-like APH PF01636.18 AIN99070.1 - 0.0058 16.4 0.0 0.014 15.1 0.0 1.7 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 AIN99070.1 - 0.015 14.3 0.0 0.025 13.6 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 AIN99070.1 - 0.016 14.5 0.0 0.028 13.7 0.0 1.3 1 0 0 1 1 1 0 RIO1 family Choline_kinase PF01633.15 AIN99070.1 - 0.089 12.3 0.0 0.14 11.6 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase HpcH_HpaI PF03328.9 AIN99072.1 - 9.9e-54 181.5 0.0 1.1e-53 181.3 0.0 1.0 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family rRNA_methylase PF06962.7 AIN99072.1 - 0.03 14.0 0.0 0.078 12.6 0.0 1.6 2 0 0 2 2 2 0 Putative rRNA methylase DHQS PF01959.11 AIN99072.1 - 0.16 10.6 0.0 0.23 10.0 0.0 1.2 1 0 0 1 1 1 0 3-dehydroquinate synthase (EC 4.6.1.3) AAA_16 PF13191.1 AIN99073.1 - 0.00088 19.3 0.0 0.0016 18.5 0.0 1.5 1 1 0 1 1 1 1 AAA ATPase domain Zeta_toxin PF06414.7 AIN99073.1 - 0.0022 17.0 0.0 0.054 12.5 0.0 2.2 1 1 0 1 1 1 1 Zeta toxin Rad17 PF03215.10 AIN99073.1 - 0.0034 16.1 0.1 0.0053 15.5 0.1 1.3 1 0 0 1 1 1 1 Rad17 cell cycle checkpoint protein AAA_17 PF13207.1 AIN99073.1 - 0.0086 16.8 0.1 0.032 15.0 0.1 2.1 1 1 0 1 1 1 1 AAA domain SRP54 PF00448.17 AIN99073.1 - 0.014 14.8 0.7 0.076 12.4 0.3 2.1 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_30 PF13604.1 AIN99073.1 - 0.017 14.6 0.3 0.048 13.2 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.1 AIN99073.1 - 0.07 13.4 0.2 0.13 12.5 0.1 1.7 1 1 0 1 1 1 0 AAA domain PIF1 PF05970.9 AIN99073.1 - 0.071 12.0 0.0 0.11 11.3 0.0 1.2 1 0 0 1 1 1 0 PIF1-like helicase NIF PF03031.13 AIN99074.1 - 5e-47 159.5 0.1 7.9e-47 158.8 0.1 1.3 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase RST PF12174.3 AIN99074.1 - 0.026 14.2 1.8 0.033 13.9 0.1 2.0 2 0 0 2 2 2 0 RCD1-SRO-TAF4 (RST) plant domain SNF2_N PF00176.18 AIN99076.1 - 4.9e-47 160.1 0.1 7.1e-47 159.6 0.1 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 AIN99076.1 - 3.4e-11 42.8 0.0 8.2e-11 41.6 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain PHD PF00628.24 AIN99076.1 - 2.8e-07 30.1 15.5 0.00035 20.2 3.4 2.6 2 0 0 2 2 2 2 PHD-finger DEAD PF00270.24 AIN99076.1 - 3.5e-05 23.3 0.0 6.7e-05 22.4 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase HDA2-3 PF11496.3 AIN99076.1 - 0.00022 20.1 0.0 0.00054 18.8 0.0 1.5 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 zf-PHD-like PF15446.1 AIN99076.1 - 0.0062 15.8 9.7 0.018 14.3 1.1 2.5 2 0 0 2 2 2 2 PHD/FYVE-zinc-finger like domain C1_1 PF00130.17 AIN99076.1 - 0.0091 15.7 4.1 0.0091 15.7 2.8 2.7 2 0 0 2 2 2 1 Phorbol esters/diacylglycerol binding domain (C1 domain) Prok-RING_1 PF14446.1 AIN99076.1 - 2.3 7.9 21.4 0.18 11.5 4.4 2.7 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 SpoIIE PF07228.7 AIN99077.1 - 1.1e-15 57.8 0.0 3.8e-14 52.8 0.0 2.1 2 0 0 2 2 2 1 Stage II sporulation protein E (SpoIIE) PP2C_2 PF13672.1 AIN99077.1 - 1.4e-05 24.6 0.2 3.4e-05 23.3 0.2 1.5 1 1 0 1 1 1 1 Protein phosphatase 2C PP2C PF00481.16 AIN99077.1 - 0.00011 21.7 0.1 0.0026 17.1 0.0 2.2 2 0 0 2 2 2 1 Protein phosphatase 2C Rieske PF00355.21 AIN99078.1 - 5.1e-07 29.1 0.3 1.1e-06 28.0 0.2 1.5 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Rieske_2 PF13806.1 AIN99078.1 - 7.1e-07 28.8 0.0 1.4e-06 27.9 0.0 1.4 1 0 0 1 1 1 1 Rieske-like [2Fe-2S] domain GTP_EFTU PF00009.22 AIN99079.1 - 2e-46 157.7 0.0 3.3e-46 157.1 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.19 AIN99079.1 - 8.9e-14 51.1 0.0 2.3e-13 49.8 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_IV PF03764.13 AIN99079.1 - 1.8e-06 27.4 0.0 4e-06 26.3 0.0 1.5 1 0 0 1 1 1 1 Elongation factor G, domain IV GTP_EFTU_D2 PF03144.20 AIN99079.1 - 1.2e-05 25.3 0.0 2.8e-05 24.1 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_II PF14492.1 AIN99079.1 - 0.00086 19.1 0.1 0.0029 17.4 0.0 1.9 2 0 0 2 2 2 1 Elongation Factor G, domain II Miro PF08477.8 AIN99079.1 - 0.17 12.3 0.0 0.37 11.3 0.0 1.6 1 0 0 1 1 1 0 Miro-like protein mRNA_triPase PF02940.10 AIN99081.1 - 1e-32 113.6 0.0 1.7e-32 112.8 0.0 1.3 1 0 0 1 1 1 1 mRNA capping enzyme, beta chain HCV_NS5a_1b PF08301.8 AIN99081.1 - 0.00042 20.6 0.8 0.0062 16.8 0.0 2.7 3 0 0 3 3 3 1 Hepatitis C virus non-structural 5a domain 1b TPR_11 PF13414.1 AIN99082.1 - 1.8e-20 72.3 37.0 1.6e-07 30.8 1.8 4.8 1 1 5 6 6 6 6 TPR repeat TPR_2 PF07719.12 AIN99082.1 - 1.5e-19 68.2 29.7 0.005 16.6 0.0 7.3 6 1 1 7 7 7 6 Tetratricopeptide repeat TPR_1 PF00515.23 AIN99082.1 - 8.1e-16 56.8 24.5 0.00011 21.6 0.0 6.9 6 1 1 7 7 7 5 Tetratricopeptide repeat TPR_12 PF13424.1 AIN99082.1 - 3e-08 33.4 19.3 0.003 17.4 0.1 4.4 2 1 2 4 4 4 4 Tetratricopeptide repeat TPR_14 PF13428.1 AIN99082.1 - 8.7e-08 32.1 14.7 0.06 14.0 0.1 6.5 2 2 4 6 6 6 2 Tetratricopeptide repeat TPR_16 PF13432.1 AIN99082.1 - 3.8e-07 30.5 28.6 0.044 14.4 1.1 5.0 3 2 3 6 6 5 5 Tetratricopeptide repeat TPR_8 PF13181.1 AIN99082.1 - 9.2e-07 28.2 23.2 0.071 12.9 0.1 6.7 6 1 1 7 7 7 3 Tetratricopeptide repeat TPR_19 PF14559.1 AIN99082.1 - 1e-06 28.9 12.7 0.55 10.6 0.1 4.6 2 2 1 4 4 4 4 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 AIN99082.1 - 0.0002 21.1 3.9 0.11 12.3 0.0 3.5 3 0 0 3 3 3 2 Fis1 C-terminal tetratricopeptide repeat TPR_17 PF13431.1 AIN99082.1 - 0.0024 17.9 10.5 2.7 8.4 0.0 6.0 7 1 0 7 7 7 2 Tetratricopeptide repeat zf-CCHC PF00098.18 AIN99082.1 - 0.052 13.5 1.4 0.11 12.4 0.9 1.5 1 0 0 1 1 1 0 Zinc knuckle MIT PF04212.13 AIN99082.1 - 1.2 9.1 10.5 3.7 7.5 0.1 4.1 3 2 0 3 3 3 0 MIT (microtubule interacting and transport) domain TPR_9 PF13371.1 AIN99082.1 - 1.4 8.8 8.5 4.7 7.1 0.1 4.0 2 1 3 5 5 5 0 Tetratricopeptide repeat TPR_6 PF13174.1 AIN99082.1 - 2.4 8.8 12.9 6.2 7.5 0.1 5.6 6 1 0 6 6 6 0 Tetratricopeptide repeat KBP_C PF12309.3 AIN99083.1 - 8.3e-89 298.1 0.0 1.5e-88 297.2 0.0 1.5 1 0 0 1 1 1 1 KIF-1 binding protein C terminal TPR_7 PF13176.1 AIN99083.1 - 0.15 11.9 1.6 3.3 7.7 0.0 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat eIF3_subunit PF08597.5 AIN99084.1 - 0.00011 21.9 17.2 0.061 12.8 8.2 2.1 2 0 0 2 2 2 2 Translation initiation factor eIF3 subunit tRNA-Thr_ED PF08915.6 AIN99084.1 - 0.62 10.0 4.2 0.53 10.2 1.3 1.9 2 0 0 2 2 2 0 Archaea-specific editing domain of threonyl-tRNA synthetase DUF3987 PF13148.1 AIN99084.1 - 7.9 4.9 9.1 2.1 6.8 4.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3987) CoA_binding PF02629.14 AIN99085.1 - 3e-25 88.5 2.3 3e-25 88.5 1.6 2.2 3 0 0 3 3 3 1 CoA binding domain Ligase_CoA PF00549.14 AIN99085.1 - 2.2e-22 79.3 1.5 2.2e-22 79.2 0.1 1.7 2 0 0 2 2 2 1 CoA-ligase Succ_CoA_lig PF13607.1 AIN99085.1 - 2.2e-07 30.5 0.0 4.3e-07 29.6 0.0 1.5 1 0 0 1 1 1 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.1 AIN99085.1 - 0.0001 22.4 0.1 0.00021 21.4 0.1 1.5 1 0 0 1 1 1 1 CoA binding domain GFO_IDH_MocA PF01408.17 AIN99085.1 - 0.079 13.4 0.1 0.14 12.6 0.1 1.4 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold BRO1 PF03097.13 AIN99086.1 - 7.2e-26 90.8 0.5 9.5e-26 90.4 0.3 1.1 1 0 0 1 1 1 1 BRO1-like domain ATG16 PF08614.6 AIN99087.1 - 0.054 13.3 1.5 0.079 12.7 1.0 1.2 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) Baculo_LEF-2 PF03041.9 AIN99087.1 - 0.066 12.8 0.3 0.11 12.1 0.2 1.3 1 0 0 1 1 1 0 lef-2 Rad60-SLD PF11976.3 AIN99088.1 - 3.1e-06 26.7 0.3 5.1e-06 26.0 0.2 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.18 AIN99088.1 - 2.9e-05 23.3 0.1 5.3e-05 22.5 0.1 1.4 1 0 0 1 1 1 1 Ubiquitin family MobB PF03205.9 AIN99089.1 - 0.013 15.2 0.0 0.023 14.4 0.0 1.4 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B CbiA PF01656.18 AIN99089.1 - 0.095 12.0 0.0 3.5 7.0 0.0 2.2 2 0 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain Sec1 PF00995.18 AIN99090.1 - 4.5e-84 283.0 0.0 5.7e-84 282.7 0.0 1.0 1 0 0 1 1 1 1 Sec1 family DnaJ PF00226.26 AIN99091.1 - 2.1e-23 81.7 4.5 5.5e-23 80.4 3.1 1.8 1 0 0 1 1 1 1 DnaJ domain zf-C2H2_jaz PF12171.3 AIN99091.1 - 7.2e-10 38.7 4.9 1.5e-09 37.7 3.4 1.6 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 AIN99091.1 - 2.4e-08 33.8 2.9 4.4e-08 33.0 2.0 1.4 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.2 AIN99091.1 - 3.7e-05 23.7 0.3 0.00018 21.5 0.1 2.2 2 0 0 2 2 2 1 C2H2 type zinc-finger (2 copies) AKAP95 PF04988.7 AIN99091.1 - 0.0056 16.4 0.2 0.015 15.0 0.1 1.7 1 0 0 1 1 1 1 A-kinase anchoring protein 95 (AKAP95) zf-C2H2 PF00096.21 AIN99091.1 - 0.015 15.6 1.7 0.034 14.4 1.2 1.7 1 0 0 1 1 1 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 AIN99091.1 - 0.016 15.4 1.3 0.05 13.9 0.9 1.9 1 0 0 1 1 1 0 C2H2-type zinc finger zf-C2H2_6 PF13912.1 AIN99091.1 - 0.16 11.8 3.9 0.11 12.4 1.2 1.9 2 0 0 2 2 2 0 C2H2-type zinc finger Evr1_Alr PF04777.8 AIN99091.1 - 0.28 11.0 2.4 13 5.7 0.1 2.6 2 0 0 2 2 2 0 Erv1 / Alr family ParcG PF10274.4 AIN99092.1 - 1.1e-78 263.2 0.0 1.6e-78 262.8 0.0 1.2 1 0 0 1 1 1 1 Parkin co-regulated protein PCI PF01399.22 AIN99093.1 - 6.2e-07 29.6 0.1 1.8e-06 28.1 0.0 1.8 2 0 0 2 2 2 1 PCI domain TPR_11 PF13414.1 AIN99093.1 - 0.0025 17.4 0.5 0.32 10.6 0.0 3.2 3 0 0 3 3 3 1 TPR repeat TPR_9 PF13371.1 AIN99093.1 - 0.13 12.1 2.1 3 7.7 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.12 AIN99093.1 - 0.32 11.0 5.1 3.8 7.6 0.1 4.3 5 0 0 5 5 5 0 Tetratricopeptide repeat DUF4160 PF13711.1 AIN99094.1 - 0.088 12.6 0.0 0.25 11.2 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4160) Cluap1 PF10234.4 AIN99094.1 - 0.45 9.6 8.3 0.8 8.8 5.8 1.4 1 0 0 1 1 1 0 Clusterin-associated protein-1 Phage_Mu_Gam PF07352.7 AIN99094.1 - 2 7.9 7.1 13 5.3 0.1 2.9 3 0 0 3 3 3 0 Bacteriophage Mu Gam like protein DUF4446 PF14584.1 AIN99094.1 - 7 6.4 6.9 6.5 6.5 1.2 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF4446) TBPIP PF07106.8 AIN99094.1 - 9.6 5.7 13.0 11 5.4 2.8 2.3 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Pex2_Pex12 PF04757.9 AIN99095.1 - 7.1e-30 104.1 14.6 9e-30 103.7 10.1 1.1 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4 PF00097.20 AIN99095.1 - 0.02 14.5 13.0 0.032 13.9 9.0 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 AIN99095.1 - 0.028 14.4 11.0 0.034 14.1 7.1 1.5 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 AIN99095.1 - 0.064 13.1 10.8 0.12 12.3 7.5 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING TF_Zn_Ribbon PF08271.7 AIN99095.1 - 0.11 11.8 5.3 0.051 12.9 1.2 2.1 2 0 0 2 2 2 0 TFIIB zinc-binding zf-RING_5 PF14634.1 AIN99095.1 - 0.13 12.0 12.9 0.2 11.4 8.9 1.3 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4_3 PF13920.1 AIN99095.1 - 4.2 7.1 13.9 6.6 6.4 9.6 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 AIN99095.1 - 7.4 6.4 13.6 17 5.3 9.4 1.6 1 1 0 1 1 1 0 Ring finger domain PHD PF00628.24 AIN99096.1 - 3.1e-06 26.7 14.7 4.3e-06 26.3 5.4 2.5 2 0 0 2 2 2 2 PHD-finger zf-PHD-like PF15446.1 AIN99096.1 - 0.047 12.9 6.6 0.047 12.9 1.6 2.1 2 0 0 2 2 2 0 PHD/FYVE-zinc-finger like domain DUF1719 PF08224.6 AIN99096.1 - 0.083 11.9 0.8 0.18 10.9 0.5 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF1719) zf-C4_ClpX PF06689.8 AIN99096.1 - 0.19 11.2 3.1 0.86 9.1 2.1 2.1 1 1 0 1 1 1 0 ClpX C4-type zinc finger Prok-RING_1 PF14446.1 AIN99096.1 - 5.3 6.8 13.0 2.7 7.7 4.3 2.5 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 UbiA PF01040.13 AIN99098.1 - 0.099 11.8 0.1 0.12 11.5 0.0 1.1 1 0 0 1 1 1 0 UbiA prenyltransferase family ABC2_membrane_4 PF12730.2 AIN99099.1 - 0.068 12.3 0.0 0.068 12.3 0.0 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein zf-DHHC PF01529.15 AIN99101.1 - 2.8e-34 117.9 1.7 2.8e-34 117.9 1.2 1.8 1 1 1 2 2 2 1 DHHC palmitoyltransferase DUF1469 PF07332.6 AIN99101.1 - 0.19 11.4 0.2 0.19 11.4 0.1 2.1 3 0 0 3 3 3 0 Protein of unknown function (DUF1469) DsbB PF02600.11 AIN99101.1 - 0.4 10.4 7.8 4.5 7.0 0.0 3.2 3 0 0 3 3 3 0 Disulfide bond formation protein DsbB Pex2_Pex12 PF04757.9 AIN99102.1 - 8.1e-14 51.5 0.1 4e-07 29.6 0.0 2.1 1 1 1 2 2 2 2 Pex2 / Pex12 amino terminal region zf-C3HC4_3 PF13920.1 AIN99102.1 - 1.1e-08 34.5 10.6 1.7e-08 34.0 7.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 AIN99102.1 - 2e-08 33.9 11.7 3.2e-08 33.2 8.1 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 AIN99102.1 - 3.9e-08 33.1 12.9 6.4e-08 32.4 9.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 AIN99102.1 - 4.3e-08 32.7 10.5 7.2e-08 32.0 7.3 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 AIN99102.1 - 2.6e-06 26.9 12.0 4.1e-06 26.3 8.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 AIN99102.1 - 1.2e-05 25.3 5.6 2e-05 24.5 3.9 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger zf-Apc11 PF12861.2 AIN99102.1 - 1.2e-05 25.0 5.3 2.1e-05 24.3 3.7 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_4 PF15227.1 AIN99102.1 - 2.1e-05 24.2 11.4 3.9e-05 23.4 7.9 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 AIN99102.1 - 0.0022 17.6 3.3 0.0023 17.6 1.2 1.8 1 1 1 2 2 2 1 RING-type zinc-finger TerY-C PF15616.1 AIN99102.1 - 0.0099 15.8 2.9 0.016 15.1 2.0 1.2 1 0 0 1 1 1 1 TerY-C metal binding domain TRAM_LAG1_CLN8 PF03798.11 AIN99102.1 - 0.019 14.5 0.6 0.029 13.9 0.4 1.3 1 0 0 1 1 1 0 TLC domain U-box PF04564.10 AIN99102.1 - 0.11 12.4 0.0 0.25 11.3 0.0 1.5 1 0 0 1 1 1 0 U-box domain zf-RING_6 PF14835.1 AIN99102.1 - 0.18 11.5 6.0 0.48 10.2 3.5 2.0 2 0 0 2 2 2 0 zf-RING of BARD1-type protein zf-Di19 PF05605.7 AIN99102.1 - 0.21 11.7 2.4 0.32 11.1 0.1 2.2 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-Nse PF11789.3 AIN99102.1 - 1.4 8.5 5.0 3 7.4 3.4 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit IBR PF01485.16 AIN99102.1 - 2.6 7.9 11.2 9.3 6.2 7.7 1.9 1 1 0 1 1 1 0 IBR domain zf-RING_4 PF14570.1 AIN99102.1 - 4.8 6.8 11.8 14 5.3 8.2 1.8 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain FANCL_C PF11793.3 AIN99102.1 - 6.9 6.7 10.3 51 3.9 7.2 2.2 1 1 0 1 1 1 0 FANCL C-terminal domain LRR_4 PF12799.2 AIN99103.1 - 7.8e-13 47.7 10.4 7.5e-07 28.6 0.5 3.1 1 1 2 3 3 3 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 AIN99103.1 - 2.7e-10 39.8 12.5 2.2e-06 27.2 1.8 2.4 1 1 1 2 2 2 2 Leucine rich repeat EF-hand_7 PF13499.1 AIN99103.1 - 2.8e-06 27.3 0.0 1.1e-05 25.4 0.0 2.1 1 0 0 1 1 1 1 EF-hand domain pair LRR_7 PF13504.1 AIN99103.1 - 4.4e-05 23.0 4.8 0.13 12.5 0.3 4.2 3 0 0 3 3 3 2 Leucine rich repeat LRR_1 PF00560.28 AIN99103.1 - 0.00024 20.7 4.9 0.79 9.9 0.2 3.9 3 0 0 3 3 3 2 Leucine Rich Repeat LRR_6 PF13516.1 AIN99103.1 - 0.00034 20.3 2.8 0.48 10.6 0.0 3.4 2 1 2 4 4 3 2 Leucine Rich repeat EF-hand_1 PF00036.27 AIN99103.1 - 0.002 17.3 0.3 0.026 13.8 0.0 3.0 3 0 0 3 3 3 1 EF hand EF-hand_8 PF13833.1 AIN99103.1 - 0.0089 15.6 0.1 0.2 11.2 0.0 2.9 1 1 1 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.1 AIN99103.1 - 0.028 14.3 0.0 0.17 11.8 0.0 2.4 1 0 0 1 1 1 0 EF-hand domain MBD_C PF14048.1 AIN99103.1 - 0.088 13.4 0.0 7 7.3 0.0 2.8 2 0 0 2 2 2 0 C-terminal domain of methyl-CpG binding protein 2 and 3 Barttin PF15462.1 AIN99103.1 - 0.16 11.6 0.1 0.31 10.6 0.1 1.4 1 0 0 1 1 1 0 Bartter syndrome, infantile, with sensorineural deafness (Barttin) DUF4352 PF11611.3 AIN99104.1 - 0.01 16.0 0.1 0.023 14.8 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4352) UPF0240 PF06784.6 AIN99104.1 - 0.038 13.6 0.1 0.3 10.7 0.0 2.1 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0240) SPC12 PF06645.8 AIN99105.1 - 4e-07 29.7 0.6 5.6e-07 29.2 0.4 1.2 1 0 0 1 1 1 1 Microsomal signal peptidase 12 kDa subunit (SPC12) Inhibitor_I34 PF10466.4 AIN99105.1 - 0.086 12.9 0.1 0.34 11.0 0.2 1.8 2 0 0 2 2 2 0 Saccharopepsin inhibitor I34 COX14 PF14880.1 AIN99105.1 - 0.19 11.3 1.1 0.57 9.8 0.8 1.8 1 1 0 1 1 1 0 Cytochrome oxidase c assembly Col_cuticle_N PF01484.12 AIN99105.1 - 2.2 8.0 4.4 0.36 10.5 0.5 1.6 2 0 0 2 2 2 0 Nematode cuticle collagen N-terminal domain VPS9 PF02204.13 AIN99106.1 - 1e-12 47.9 0.1 1.6e-12 47.3 0.0 1.3 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain MORN PF02493.15 AIN99106.1 - 4e-08 32.5 6.3 5.9e-06 25.6 0.4 3.9 3 0 0 3 3 3 2 MORN repeat Cellulase-like PF12876.2 AIN99106.1 - 0.063 13.7 0.0 0.15 12.4 0.0 1.7 1 0 0 1 1 1 0 Sugar-binding cellulase-like Pkinase PF00069.20 AIN99107.1 - 1.4e-68 230.8 0.0 2.2e-68 230.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AIN99107.1 - 1.4e-39 135.7 0.0 2.1e-39 135.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 AIN99107.1 - 1.3e-07 30.8 0.0 2.6e-07 29.8 0.0 1.5 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 AIN99107.1 - 0.0076 15.3 0.0 0.013 14.5 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 AIN99107.1 - 0.014 15.1 0.0 0.45 10.1 0.0 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family Cob_adeno_trans PF01923.13 AIN99108.1 - 0.016 15.0 0.3 0.03 14.1 0.2 1.4 1 0 0 1 1 1 0 Cobalamin adenosyltransferase DUF3466 PF11949.3 AIN99108.1 - 0.031 12.8 0.0 0.038 12.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3466) ADK PF00406.17 AIN99110.1 - 1.2e-36 125.9 0.0 1.4e-36 125.6 0.0 1.0 1 0 0 1 1 1 1 Adenylate kinase ADK_lid PF05191.9 AIN99110.1 - 1.2e-18 66.4 3.7 1.9e-18 65.8 2.5 1.3 1 0 0 1 1 1 1 Adenylate kinase, active site lid AAA_17 PF13207.1 AIN99110.1 - 1.8e-08 35.1 0.0 2.7e-08 34.6 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 AIN99110.1 - 0.00027 21.2 0.0 0.00037 20.7 0.0 1.2 1 0 0 1 1 1 1 AAA domain A2L_zn_ribbon PF08792.5 AIN99110.1 - 0.0016 17.8 0.5 0.46 10.0 0.0 2.5 2 0 0 2 2 2 2 A2L zinc ribbon domain AAA_33 PF13671.1 AIN99110.1 - 0.0031 17.3 0.0 0.006 16.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain NTPase_1 PF03266.10 AIN99110.1 - 0.058 13.0 0.0 0.11 12.1 0.0 1.5 1 0 0 1 1 1 0 NTPase zf-C2H2_3 PF13878.1 AIN99110.1 - 0.86 9.2 0.0 0.86 9.2 0.0 2.0 2 0 0 2 2 2 0 zinc-finger of acetyl-transferase ESCO Arv1 PF04161.8 AIN99112.1 - 1.2e-19 71.0 2.5 1.7e-19 70.5 1.7 1.3 1 0 0 1 1 1 1 Arv1-like family PHA-1 PF06542.6 AIN99112.1 - 0.067 11.9 0.2 0.084 11.5 0.2 1.1 1 0 0 1 1 1 0 Regulator protein PHA-1 NOG1 PF06858.9 AIN99112.1 - 0.12 12.2 0.0 0.23 11.3 0.0 1.5 1 0 0 1 1 1 0 Nucleolar GTP-binding protein 1 (NOG1) DUF360 PF04020.8 AIN99112.1 - 3.5 8.0 12.2 4.3 7.7 2.4 2.6 1 1 1 2 2 2 0 Membrane protein of unknown function Creatinase_N PF01321.13 AIN99115.1 - 1.7e-21 77.0 0.2 1e-17 64.8 0.0 2.3 2 1 0 2 2 2 2 Creatinase/Prolidase N-terminal domain LSM PF01423.17 AIN99117.1 - 1.2e-11 44.0 0.1 1.5e-11 43.6 0.1 1.2 1 0 0 1 1 1 1 LSM domain Brix PF04427.13 AIN99118.1 - 4.1e-35 121.1 0.0 6.7e-35 120.4 0.0 1.3 1 0 0 1 1 1 1 Brix domain Glyoxalase_4 PF13669.1 AIN99119.1 - 1.6e-17 63.4 0.0 1.9e-17 63.2 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_3 PF13468.1 AIN99119.1 - 0.0064 16.4 0.0 0.0075 16.1 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase_2 PF12681.2 AIN99119.1 - 0.0073 16.8 0.0 0.013 16.0 0.0 1.5 1 1 1 2 2 2 1 Glyoxalase-like domain Glyoxalase PF00903.20 AIN99119.1 - 0.03 14.3 0.0 0.037 13.9 0.0 1.2 1 0 0 1 1 1 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily GDC-P PF02347.11 AIN99120.1 - 2.4e-172 573.4 0.0 1.5e-155 518.1 0.1 3.1 3 0 0 3 3 3 3 Glycine cleavage system P-protein Beta_elim_lyase PF01212.16 AIN99120.1 - 0.00014 21.1 0.0 0.00034 19.8 0.0 1.6 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.14 AIN99120.1 - 0.00066 18.5 0.2 0.36 9.5 0.0 2.4 2 1 0 2 2 2 2 Aminotransferase class-V Cys_Met_Meta_PP PF01053.15 AIN99120.1 - 0.0065 14.7 0.1 0.019 13.2 0.0 1.8 2 0 0 2 2 2 1 Cys/Met metabolism PLP-dependent enzyme DUF4473 PF14747.1 AIN99120.1 - 0.0099 16.0 0.0 0.046 13.9 0.0 2.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4473) Pkinase PF00069.20 AIN99121.1 - 1.2e-55 188.4 0.0 1.4e-55 188.2 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AIN99121.1 - 2.8e-23 82.3 0.0 3e-23 82.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 AIN99121.1 - 4.6e-05 22.5 0.0 0.0002 20.4 0.0 1.8 2 0 0 2 2 2 1 Kinase-like Rhomboid PF01694.17 AIN99127.1 - 0.001 19.1 4.3 0.0049 16.9 3.0 2.0 1 1 0 1 1 1 1 Rhomboid family MauE PF07291.6 AIN99127.1 - 0.076 12.6 0.1 0.14 11.7 0.1 1.4 1 0 0 1 1 1 0 Methylamine utilisation protein MauE Pribosyltran PF00156.22 AIN99128.1 - 8.1e-18 64.3 0.0 1.1e-17 63.8 0.0 1.2 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.1 AIN99128.1 - 0.00025 20.3 0.0 0.00035 19.8 0.0 1.2 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase PRTase_2 PF15609.1 AIN99128.1 - 0.0018 17.6 0.0 0.0043 16.3 0.0 1.7 1 1 0 1 1 1 1 Phosphoribosyl transferase Racemase_4 PF13615.1 AIN99129.1 - 4.7e-20 71.7 0.3 1e-19 70.6 0.2 1.6 1 0 0 1 1 1 1 Putative alanine racemase MCM_bind PF09739.4 AIN99129.1 - 1.1e-12 47.5 0.0 2.7e-12 46.3 0.0 1.7 1 1 0 1 1 1 1 Mini-chromosome maintenance replisome factor NIF PF03031.13 AIN99130.1 - 7e-48 162.2 0.1 1e-47 161.7 0.1 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Actino_peptide PF14408.1 AIN99130.1 - 0.093 12.6 1.2 0.22 11.4 0.8 1.5 1 0 0 1 1 1 0 Ribosomally synthesized peptide in actinomycetes Ribosomal_L30 PF00327.15 AIN99131.1 - 4.3e-19 67.8 1.4 4.3e-19 67.8 1.0 1.8 2 0 0 2 2 2 1 Ribosomal protein L30p/L7e Ribosomal_L30_N PF08079.7 AIN99131.1 - 4.8e-15 55.3 11.2 9.6e-15 54.3 7.7 1.5 1 0 0 1 1 1 1 Ribosomal L30 N-terminal domain Nfu_N PF08712.6 AIN99133.1 - 4.3e-23 80.7 0.0 7.8e-23 79.9 0.0 1.4 1 0 0 1 1 1 1 Scaffold protein Nfu/NifU N terminal NifU PF01106.12 AIN99133.1 - 6e-23 80.3 0.3 1.2e-22 79.4 0.0 1.6 2 0 0 2 2 2 1 NifU-like domain eRF1_1 PF03463.10 AIN99134.1 - 3.5e-33 113.9 0.4 7.5e-33 112.9 0.1 1.7 2 0 0 2 2 2 1 eRF1 domain 1 eRF1_2 PF03464.10 AIN99134.1 - 6e-21 75.1 0.1 9.7e-21 74.4 0.1 1.3 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.10 AIN99134.1 - 3.5e-14 53.0 0.0 1.3e-13 51.1 0.0 2.0 2 1 0 2 2 2 1 eRF1 domain 3 DUF3145 PF11343.3 AIN99134.1 - 0.064 12.6 0.0 0.22 10.9 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3145) SIR2 PF02146.12 AIN99135.1 - 1.6e-56 190.8 0.0 2.1e-56 190.4 0.0 1.2 1 0 0 1 1 1 1 Sir2 family zinc_ribbon_4 PF13717.1 AIN99135.1 - 0.007 16.0 1.8 0.016 14.9 0.2 2.1 2 0 0 2 2 2 1 zinc-ribbon domain zinc_ribbon_5 PF13719.1 AIN99135.1 - 0.0096 15.4 1.7 0.018 14.6 0.2 2.0 2 0 0 2 2 2 1 zinc-ribbon domain Paired_CXXCH_1 PF09699.5 AIN99135.1 - 0.027 13.9 0.6 0.056 12.9 0.4 1.5 1 0 0 1 1 1 0 Doubled CXXCH motif (Paired_CXXCH_1) DUF2305 PF10230.4 AIN99136.1 - 3.5e-61 206.9 0.0 4.1e-61 206.7 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2305) Abhydrolase_6 PF12697.2 AIN99136.1 - 2e-13 50.7 0.0 2.4e-13 50.4 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 AIN99136.1 - 8.4e-12 45.0 0.0 2.7e-11 43.4 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 AIN99136.1 - 0.0017 17.9 0.0 0.003 17.1 0.0 1.4 1 0 0 1 1 1 1 PGAP1-like protein DUF1057 PF06342.7 AIN99136.1 - 0.0049 15.7 0.0 0.0064 15.3 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1057) Abhydrolase_1 PF00561.15 AIN99136.1 - 0.0064 16.0 0.0 0.015 14.9 0.0 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.3 AIN99136.1 - 0.025 14.4 0.0 0.079 12.8 0.0 1.8 2 0 0 2 2 2 0 Putative lysophospholipase Lipase_3 PF01764.20 AIN99136.1 - 0.058 13.0 0.0 0.13 11.8 0.0 1.6 1 0 0 1 1 1 0 Lipase (class 3) HALZ PF02183.13 AIN99137.1 - 0.015 14.9 0.0 0.044 13.5 0.0 1.7 1 0 0 1 1 1 0 Homeobox associated leucine zipper Rootletin PF15035.1 AIN99137.1 - 0.26 11.2 1.8 0.77 9.7 0.3 2.1 2 0 0 2 2 2 0 Ciliary rootlet component, centrosome cohesion IF4E PF01652.13 AIN99138.1 - 5.5e-12 45.5 0.0 6.9e-12 45.2 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E ANTAR PF03861.9 AIN99139.1 - 0.019 14.5 0.5 0.066 12.8 0.4 2.0 1 0 0 1 1 1 0 ANTAR domain Phage_min_cap2 PF06152.6 AIN99139.1 - 0.52 9.2 0.0 0.79 8.6 0.0 1.2 1 0 0 1 1 1 0 Phage minor capsid protein 2 MMR_HSR1 PF01926.18 AIN99141.1 - 1.1e-37 128.4 0.1 1.3e-19 70.2 0.0 2.6 3 0 0 3 3 3 2 50S ribosome-binding GTPase GTP_EFTU PF00009.22 AIN99141.1 - 1.6e-24 86.4 0.8 1.2e-11 44.4 0.0 3.5 2 1 0 2 2 2 2 Elongation factor Tu GTP binding domain Dynamin_N PF00350.18 AIN99141.1 - 3.1e-16 59.6 0.1 0.00038 20.3 0.0 4.5 3 1 1 4 4 4 4 Dynamin family FeoB_N PF02421.13 AIN99141.1 - 4.3e-16 58.5 0.1 9.5e-08 31.4 0.0 2.4 2 0 0 2 2 2 2 Ferrous iron transport protein B KH_dom-like PF14714.1 AIN99141.1 - 7.5e-15 54.6 0.4 1.6e-14 53.6 0.3 1.6 1 0 0 1 1 1 1 KH-domain-like of EngA bacterial GTPase enzymes, C-terminal Miro PF08477.8 AIN99141.1 - 4.7e-14 52.9 0.0 6.3e-07 29.9 0.0 2.8 2 0 0 2 2 2 2 Miro-like protein AIG1 PF04548.11 AIN99141.1 - 1.6e-11 43.7 0.1 1.4e-06 27.5 0.0 2.7 3 0 0 3 3 3 2 AIG1 family SRPRB PF09439.5 AIN99141.1 - 4.4e-09 35.8 0.0 0.00035 19.8 0.0 2.4 2 0 0 2 2 2 2 Signal recognition particle receptor beta subunit Ras PF00071.17 AIN99141.1 - 1.3e-08 34.4 0.0 1.1e-06 28.1 0.0 2.6 2 1 0 2 2 2 1 Ras family DUF258 PF03193.11 AIN99141.1 - 6.6e-05 22.1 0.0 0.14 11.3 0.0 2.7 2 0 0 2 2 2 2 Protein of unknown function, DUF258 PduV-EutP PF10662.4 AIN99141.1 - 7.1e-05 22.3 0.0 0.11 12.0 0.0 2.9 2 1 0 2 2 2 2 Ethanolamine utilisation - propanediol utilisation cobW PF02492.14 AIN99141.1 - 0.00011 21.7 2.0 0.11 11.9 0.2 3.3 3 1 0 3 3 3 2 CobW/HypB/UreG, nucleotide-binding domain ATP_bind_1 PF03029.12 AIN99141.1 - 0.00015 21.3 0.4 1.6 8.2 0.0 3.3 2 1 1 3 3 3 2 Conserved hypothetical ATP binding protein T2SE PF00437.15 AIN99141.1 - 0.0014 17.5 0.1 0.0037 16.1 0.0 1.8 2 1 0 2 2 2 1 Type II/IV secretion system protein Arf PF00025.16 AIN99141.1 - 0.0021 17.3 0.2 0.082 12.1 0.1 3.0 2 1 0 2 2 2 1 ADP-ribosylation factor family MobB PF03205.9 AIN99141.1 - 0.0021 17.7 0.0 0.013 15.2 0.0 2.3 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B IIGP PF05049.8 AIN99141.1 - 0.0031 16.3 0.0 0.0068 15.2 0.0 1.5 1 0 0 1 1 1 1 Interferon-inducible GTPase (IIGP) ABC_tran PF00005.22 AIN99141.1 - 0.0033 17.7 0.0 0.09 13.0 0.0 2.4 2 0 0 2 2 2 1 ABC transporter Septin PF00735.13 AIN99141.1 - 0.004 16.2 0.0 2.5 7.0 0.0 2.4 2 0 0 2 2 2 2 Septin AAA_18 PF13238.1 AIN99141.1 - 0.0057 16.9 0.0 0.16 12.2 0.0 2.6 2 0 0 2 2 2 1 AAA domain GBP PF02263.14 AIN99141.1 - 0.024 13.7 0.0 0.1 11.6 0.0 2.0 2 0 0 2 2 2 0 Guanylate-binding protein, N-terminal domain Arch_ATPase PF01637.13 AIN99141.1 - 0.052 13.2 0.0 0.21 11.2 0.0 2.0 2 0 0 2 2 2 0 Archaeal ATPase AAA_22 PF13401.1 AIN99141.1 - 0.053 13.6 0.0 2.5 8.2 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.1 AIN99141.1 - 0.19 12.5 0.9 1.9 9.2 0.0 3.0 3 2 1 4 4 2 0 AAA domain DUF4291 PF14124.1 AIN99142.1 - 0.032 13.8 0.0 0.047 13.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4291) MethyTransf_Reg PF10119.4 AIN99142.1 - 0.04 14.3 0.1 1.3 9.5 0.0 3.0 2 1 1 3 3 3 0 Predicted methyltransferase regulatory domain Ank_3 PF13606.1 AIN99142.1 - 0.1 12.9 0.2 2.7 8.5 0.0 2.8 3 0 0 3 3 3 0 Ankyrin repeat LRV PF01816.12 AIN99142.1 - 1.1 9.6 3.8 2.9 8.2 0.3 2.9 3 0 0 3 3 3 0 Leucine rich repeat variant NUDIX_2 PF13869.1 AIN99143.1 - 2.4e-40 137.8 0.0 2.5e-39 134.5 0.0 2.4 1 1 0 1 1 1 1 Nucleotide hydrolase NUDIX PF00293.23 AIN99143.1 - 0.0013 18.3 0.3 0.003 17.2 0.0 1.7 2 0 0 2 2 2 1 NUDIX domain Peptidase_M1 PF01433.15 AIN99144.1 - 3.1e-114 382.0 0.0 5.9e-114 381.1 0.0 1.4 1 1 0 1 1 1 1 Peptidase family M1 ERAP1_C PF11838.3 AIN99144.1 - 2.9e-44 151.6 0.0 4.7e-44 150.9 0.0 1.3 1 0 0 1 1 1 1 ERAP1-like C-terminal domain Peptidase_MA_2 PF13485.1 AIN99144.1 - 2.3e-18 66.4 0.5 6.6e-18 64.9 0.3 1.8 1 0 0 1 1 1 1 Peptidase MA superfamily DUF45 PF01863.12 AIN99144.1 - 0.084 12.6 0.0 0.2 11.4 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function DUF45 6PF2K PF01591.13 AIN99145.1 - 7.5e-34 116.7 0.0 1.2e-33 116.1 0.0 1.2 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.17 AIN99145.1 - 2.3e-15 57.0 0.1 6.7e-15 55.5 0.0 1.9 2 0 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) Ank_2 PF12796.2 AIN99145.1 - 1.1e-12 48.0 0.0 3.1e-12 46.6 0.0 1.8 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.1 AIN99145.1 - 4.2e-12 45.8 0.1 9.3e-12 44.7 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.25 AIN99145.1 - 1.6e-11 43.3 0.2 6.5e-07 28.8 0.0 3.6 3 0 0 3 3 3 1 Ankyrin repeat Ank_4 PF13637.1 AIN99145.1 - 3.4e-11 43.3 0.0 9e-05 22.8 0.0 2.6 1 1 1 2 2 2 2 Ankyrin repeats (many copies) AAA_33 PF13671.1 AIN99145.1 - 9.3e-07 28.8 0.1 1.8e-06 27.8 0.1 1.5 1 0 0 1 1 1 1 AAA domain Ank_3 PF13606.1 AIN99145.1 - 1.8e-06 27.6 0.0 0.00029 20.7 0.0 3.3 3 0 0 3 3 2 1 Ankyrin repeat KTI12 PF08433.5 AIN99145.1 - 0.00043 19.5 0.0 0.00088 18.5 0.0 1.6 1 1 0 1 1 1 1 Chromatin associated protein KTI12 Zeta_toxin PF06414.7 AIN99145.1 - 0.003 16.6 0.0 0.0061 15.6 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin AAA_5 PF07728.9 AIN99145.1 - 0.018 14.7 0.2 0.071 12.8 0.1 1.9 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 AIN99145.1 - 0.064 13.3 0.0 0.21 11.7 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA_17 PF13207.1 AIN99145.1 - 0.097 13.4 0.0 0.24 12.2 0.0 1.7 1 1 0 1 1 1 0 AAA domain APS_kinase PF01583.15 AIN99145.1 - 0.12 12.0 0.0 0.71 9.5 0.0 2.1 1 1 1 2 2 2 0 Adenylylsulphate kinase THF_DHG_CYH_C PF02882.14 AIN99146.1 - 8.7e-61 203.6 0.3 1.3e-60 203.0 0.2 1.3 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.18 AIN99146.1 - 7.8e-37 125.8 0.4 1.1e-36 125.3 0.3 1.2 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain Cyclin_N PF00134.18 AIN99147.1 - 4.8e-12 45.5 0.1 9.8e-12 44.5 0.1 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain DUF2637 PF10935.3 AIN99147.1 - 0.11 12.3 2.6 0.26 11.2 0.1 2.4 2 1 1 3 3 3 0 Protein of unknown function (DUF2637) DUF3782 PF12644.2 AIN99147.1 - 0.15 11.8 0.3 2.1 8.2 0.0 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF3782) Cyclin_C PF02984.14 AIN99147.1 - 0.21 11.5 2.2 0.41 10.5 0.5 2.3 1 1 1 2 2 2 0 Cyclin, C-terminal domain IU_nuc_hydro PF01156.14 AIN99148.1 - 3.9e-23 82.1 0.5 8.4e-22 77.7 0.1 2.0 1 1 1 2 2 2 2 Inosine-uridine preferring nucleoside hydrolase MIG-14_Wnt-bd PF06664.7 AIN99148.1 - 0.043 12.6 0.1 0.05 12.4 0.1 1.2 1 0 0 1 1 1 0 Wnt-binding factor required for Wnt secretion Vps52 PF04129.7 AIN99149.1 - 1.2e-48 165.9 2.2 5.7e-15 54.8 0.0 3.4 3 1 0 3 3 3 3 Vps52 / Sac2 family Sec3_C PF09763.4 AIN99149.1 - 0.01 13.9 0.1 1.2 7.2 0.0 2.2 2 0 0 2 2 2 0 Exocyst complex component Sec3 DASH_Duo1 PF08651.5 AIN99149.1 - 0.012 15.1 2.4 0.27 10.8 0.5 3.1 3 0 0 3 3 3 0 DASH complex subunit Duo1 TPR_11 PF13414.1 AIN99151.1 - 8.1e-36 121.4 22.7 2.5e-06 27.0 0.2 10.5 7 3 4 11 11 11 8 TPR repeat TPR_2 PF07719.12 AIN99151.1 - 4.4e-27 91.7 37.2 0.00078 19.1 0.0 14.8 16 1 0 16 16 15 5 Tetratricopeptide repeat TPR_1 PF00515.23 AIN99151.1 - 2.1e-24 84.0 23.1 0.0016 17.9 0.0 11.1 13 0 0 13 13 12 5 Tetratricopeptide repeat TPR_12 PF13424.1 AIN99151.1 - 4.5e-22 77.7 34.2 0.0012 18.7 0.3 11.1 9 1 2 11 11 11 7 Tetratricopeptide repeat TPR_8 PF13181.1 AIN99151.1 - 5.1e-20 69.6 1.2 0.023 14.4 0.1 10.9 14 0 0 14 14 13 4 Tetratricopeptide repeat TPR_16 PF13432.1 AIN99151.1 - 1.5e-14 54.1 22.9 0.12 13.1 0.5 10.1 8 4 1 10 10 10 3 Tetratricopeptide repeat TPR_9 PF13371.1 AIN99151.1 - 4.3e-14 52.1 31.9 0.019 14.8 0.1 10.7 8 2 2 10 10 10 6 Tetratricopeptide repeat TPR_14 PF13428.1 AIN99151.1 - 1.4e-11 43.9 36.9 0.017 15.7 0.7 12.7 10 3 5 15 15 15 3 Tetratricopeptide repeat TPR_19 PF14559.1 AIN99151.1 - 3.1e-08 33.8 15.5 0.35 11.2 0.4 8.5 7 2 2 9 9 9 2 Tetratricopeptide repeat TPR_17 PF13431.1 AIN99151.1 - 1e-06 28.4 11.3 2.7 8.4 0.1 8.8 12 0 0 12 12 9 1 Tetratricopeptide repeat Apc3 PF12895.2 AIN99151.1 - 7.6e-06 25.9 7.4 0.38 10.9 0.2 6.0 4 2 1 5 5 5 2 Anaphase-promoting complex, cyclosome, subunit 3 NARP1 PF12569.3 AIN99151.1 - 4.5e-05 22.3 0.8 0.28 9.8 0.0 3.4 3 0 0 3 3 3 2 NMDA receptor-regulated protein 1 TPR_6 PF13174.1 AIN99151.1 - 6.5e-05 23.1 12.8 19 6.0 0.0 9.3 10 0 0 10 10 9 0 Tetratricopeptide repeat TPR_7 PF13176.1 AIN99151.1 - 0.0051 16.5 23.0 1.3 8.9 0.0 10.1 11 0 0 11 11 11 1 Tetratricopeptide repeat TPR_15 PF13429.1 AIN99151.1 - 0.017 14.1 2.8 7.5 5.5 0.0 4.6 3 2 1 4 4 4 0 Tetratricopeptide repeat SHNi-TPR PF10516.4 AIN99151.1 - 0.019 14.2 5.7 2.1 7.6 0.0 5.4 6 0 0 6 6 6 0 SHNi-TPR Apc5 PF12862.2 AIN99151.1 - 0.021 14.6 6.5 1.4 8.7 0.0 5.3 5 2 0 5 5 4 0 Anaphase-promoting complex subunit 5 Fis1_TPR_C PF14853.1 AIN99151.1 - 0.05 13.4 3.0 2 8.3 0.0 4.6 5 0 0 5 5 5 0 Fis1 C-terminal tetratricopeptide repeat TPR_10 PF13374.1 AIN99151.1 - 0.84 9.6 27.8 13 5.9 0.5 8.4 9 0 0 9 9 8 0 Tetratricopeptide repeat TPR_4 PF07721.9 AIN99151.1 - 4 8.1 29.4 23 5.8 0.0 9.0 9 0 0 9 9 7 0 Tetratricopeptide repeat Ist1 PF03398.9 AIN99152.1 - 2.9e-58 195.9 0.2 3.6e-58 195.6 0.2 1.1 1 0 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway PAP_assoc PF03828.14 AIN99153.1 - 5e-15 55.1 0.1 1e-14 54.1 0.1 1.5 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.18 AIN99153.1 - 2e-06 28.0 0.0 5.7e-06 26.5 0.0 1.8 2 0 0 2 2 2 1 Nucleotidyltransferase domain 2OG-FeII_Oxy_2 PF13532.1 AIN99154.1 - 1.4e-13 51.1 0.0 1.9e-13 50.6 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 AIN99154.1 - 2.8e-07 30.7 0.0 5.2e-07 29.8 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Pan_kinase PF03309.9 AIN99154.1 - 0.028 13.9 0.0 0.049 13.1 0.0 1.4 1 0 0 1 1 1 0 Type III pantothenate kinase zf-B_box PF00643.19 AIN99155.1 - 0.035 14.0 10.5 0.16 11.8 3.1 3.0 3 0 0 3 3 3 0 B-box zinc finger zf-trcl PF13451.1 AIN99155.1 - 0.046 13.3 0.4 0.046 13.3 0.3 2.4 3 0 0 3 3 3 0 Probable zinc-binding domain DUF1091 PF06477.8 AIN99155.1 - 0.061 13.7 0.0 0.09 13.2 0.0 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1091) DUF3268 PF11672.3 AIN99155.1 - 0.11 12.6 0.3 0.11 12.6 0.2 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3268) zf-DNA_Pol PF08996.5 AIN99155.1 - 0.12 11.6 3.8 0.2 10.9 2.7 1.5 1 1 0 1 1 1 0 DNA Polymerase alpha zinc finger zf-4CXXC_R1 PF10497.4 AIN99155.1 - 0.35 11.0 8.7 0.69 10.0 6.0 1.6 1 1 0 1 1 1 0 Zinc-finger domain of monoamine-oxidase A repressor R1 PseudoU_synth_1 PF01416.15 AIN99156.1 - 6.3e-12 45.8 0.0 3.3e-07 30.6 0.0 3.2 2 1 0 2 2 2 2 tRNA pseudouridine synthase ParA PF10609.4 AIN99157.1 - 4.7e-34 116.1 0.0 8.1e-34 115.3 0.0 1.4 1 0 0 1 1 1 1 ParA/MinD ATPase like CbiA PF01656.18 AIN99157.1 - 2e-15 56.7 0.0 3.1e-15 56.1 0.0 1.3 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain ArsA_ATPase PF02374.10 AIN99157.1 - 3.5e-07 29.5 0.2 2.5e-05 23.4 0.2 2.8 3 0 0 3 3 3 1 Anion-transporting ATPase MipZ PF09140.6 AIN99157.1 - 1.7e-06 27.3 0.0 0.00014 21.0 0.0 2.1 2 0 0 2 2 2 1 ATPase MipZ AAA_31 PF13614.1 AIN99157.1 - 8.1e-06 25.8 0.0 0.00017 21.5 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.1 AIN99157.1 - 0.00083 18.8 0.1 0.0017 17.8 0.1 1.5 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 AIN99157.1 - 0.0041 16.8 0.1 0.35 10.6 0.2 2.4 2 0 0 2 2 2 1 Part of AAA domain Fer4_NifH PF00142.13 AIN99157.1 - 0.0044 16.2 0.1 0.0089 15.2 0.1 1.4 1 0 0 1 1 1 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family APS_kinase PF01583.15 AIN99157.1 - 0.027 14.1 0.0 0.048 13.3 0.0 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase ArgK PF03308.11 AIN99157.1 - 0.055 12.2 0.1 0.096 11.4 0.1 1.3 1 0 0 1 1 1 0 ArgK protein AAA_26 PF13500.1 AIN99157.1 - 0.056 13.0 0.1 3.7 7.0 0.0 2.2 2 0 0 2 2 2 0 AAA domain NACHT PF05729.7 AIN99157.1 - 0.074 12.7 0.6 0.17 11.5 0.4 1.5 1 0 0 1 1 1 0 NACHT domain AAA_17 PF13207.1 AIN99157.1 - 0.075 13.8 0.1 0.24 12.2 0.0 1.9 2 0 0 2 2 1 0 AAA domain DUF258 PF03193.11 AIN99157.1 - 0.099 11.8 0.4 0.22 10.6 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 Hpr_kinase_C PF07475.7 AIN99157.1 - 0.11 11.7 0.2 0.71 9.1 0.4 1.9 2 0 0 2 2 2 0 HPr Serine kinase C-terminal domain SRP54 PF00448.17 AIN99157.1 - 0.13 11.6 0.1 0.37 10.1 0.1 1.7 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain RNA_helicase PF00910.17 AIN99157.1 - 0.13 12.4 0.1 0.28 11.3 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_22 PF13401.1 AIN99157.1 - 0.16 12.1 0.1 0.44 10.6 0.0 1.7 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.17 AIN99157.1 - 0.23 10.2 0.3 0.37 9.5 0.2 1.2 1 0 0 1 1 1 0 NB-ARC domain DUF1358 PF07096.6 AIN99158.1 - 0.00076 19.1 0.1 0.0015 18.1 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1358) FlgN PF05130.7 AIN99158.1 - 1.3 9.2 5.1 9.7 6.4 0.5 2.2 2 0 0 2 2 2 0 FlgN protein ATP-synt_C PF00137.16 AIN99160.1 - 3.1e-17 62.2 12.5 5.2e-17 61.5 8.7 1.4 1 0 0 1 1 1 1 ATP synthase subunit C DUF2474 PF10617.4 AIN99161.1 - 0.01 15.3 0.4 0.025 14.1 0.3 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2474) ATP_bind_1 PF03029.12 AIN99162.1 - 3.3e-47 161.0 0.0 4.3e-46 157.3 0.0 2.1 1 1 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_17 PF13207.1 AIN99162.1 - 0.00048 20.9 2.1 0.0094 16.7 0.1 2.9 2 2 0 2 2 2 1 AAA domain AAA_33 PF13671.1 AIN99162.1 - 0.0044 16.9 0.4 0.014 15.2 0.0 2.1 2 1 0 2 2 2 1 AAA domain AAA_18 PF13238.1 AIN99162.1 - 0.029 14.6 1.5 0.17 12.2 0.2 2.6 3 0 0 3 3 3 0 AAA domain AAA_22 PF13401.1 AIN99162.1 - 0.036 14.2 0.0 0.17 11.9 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA PF00004.24 AIN99162.1 - 0.045 13.9 0.0 0.47 10.6 0.0 2.4 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.1 AIN99162.1 - 0.087 12.5 0.6 0.4 10.4 0.0 2.3 3 0 0 3 3 3 0 Part of AAA domain PAP_assoc PF03828.14 AIN99163.1 - 9.7e-09 35.0 0.0 2.3e-08 33.8 0.0 1.7 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.18 AIN99163.1 - 0.1 12.9 0.0 0.21 11.9 0.0 1.5 1 0 0 1 1 1 0 Nucleotidyltransferase domain LRR_6 PF13516.1 AIN99164.1 - 8.6e-27 90.1 18.4 0.18 11.9 0.0 12.3 12 0 0 12 12 12 10 Leucine Rich repeat LRR_4 PF12799.2 AIN99164.1 - 2.6e-10 39.6 16.0 0.023 14.3 0.1 6.2 4 2 2 7 7 7 6 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 AIN99164.1 - 4e-08 32.2 12.8 5.1 7.5 0.1 9.8 10 1 1 11 11 11 3 Leucine Rich Repeat LRR_7 PF13504.1 AIN99164.1 - 1.8e-06 27.2 17.3 20 5.9 0.0 9.8 10 0 0 10 10 10 1 Leucine rich repeat LRR_8 PF13855.1 AIN99164.1 - 8.6e-05 22.2 18.8 0.056 13.1 0.4 6.3 2 2 4 6 6 6 5 Leucine rich repeat DUF2652 PF10851.3 AIN99165.1 - 0.074 13.0 1.0 0.48 10.4 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2652) Glycos_transf_2 PF00535.21 AIN99167.1 - 0.0082 15.8 0.0 0.023 14.3 0.0 1.7 2 0 0 2 2 2 1 Glycosyl transferase family 2 CEP44 PF15007.1 AIN99167.1 - 0.14 11.8 0.0 0.3 10.7 0.0 1.5 1 0 0 1 1 1 0 Centrosomal spindle body, CEP44 SecG PF03840.9 AIN99167.1 - 1.5 8.6 3.5 0.88 9.3 0.2 2.1 2 0 0 2 2 2 0 Preprotein translocase SecG subunit MAPKK1_Int PF08923.5 AIN99169.1 - 0.0003 20.4 0.0 0.021 14.4 0.0 2.0 2 0 0 2 2 2 2 Mitogen-activated protein kinase kinase 1 interacting DUF2763 PF10961.3 AIN99169.1 - 0.049 14.0 0.2 0.079 13.3 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2763) DUF525 PF04379.9 AIN99170.1 - 1.3e-18 66.7 0.0 2.8e-18 65.6 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF525) Taxilin PF09728.4 AIN99172.1 - 7.8e-06 25.1 49.7 5.1e-05 22.5 33.3 2.0 1 1 0 1 1 1 1 Myosin-like coiled-coil protein Pedibin PF08182.6 AIN99172.1 - 0.27 10.7 5.8 1.4 8.4 0.3 3.0 2 0 0 2 2 2 0 Pedibin/Hym-346 family Reo_sigmaC PF04582.7 AIN99172.1 - 0.37 9.9 2.9 4.3 6.4 0.0 2.9 1 1 2 3 3 3 0 Reovirus sigma C capsid protein Filament PF00038.16 AIN99172.1 - 0.43 9.9 49.4 0.13 11.7 15.9 2.8 1 1 2 3 3 3 0 Intermediate filament protein DUF3467 PF11950.3 AIN99172.1 - 0.62 10.1 3.9 0.66 10.0 1.2 2.3 1 1 0 2 2 2 0 Protein of unknown function (DUF3467) Fib_alpha PF08702.5 AIN99172.1 - 0.92 9.6 28.6 1 9.5 6.8 3.2 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family Laminin_II PF06009.7 AIN99172.1 - 1.1 9.0 26.2 0.23 11.2 0.9 4.0 2 1 2 4 4 4 0 Laminin Domain II PPR_2 PF13041.1 AIN99173.1 - 3e-15 55.9 4.1 3.2e-07 30.2 0.1 4.0 2 2 2 4 4 4 4 PPR repeat family PPR_3 PF13812.1 AIN99173.1 - 1.4e-08 34.2 1.1 0.011 15.9 0.0 4.3 4 0 0 4 4 4 2 Pentatricopeptide repeat domain PPR PF01535.15 AIN99173.1 - 2.2e-06 27.2 7.6 0.075 13.0 0.0 5.2 5 1 0 5 5 5 2 PPR repeat PemK PF02452.12 AIN99173.1 - 0.037 14.2 0.0 0.081 13.1 0.0 1.5 1 0 0 1 1 1 0 PemK-like protein Cpn10 PF00166.16 AIN99174.1 - 1.8e-22 79.0 0.1 2e-22 78.8 0.1 1.0 1 0 0 1 1 1 1 Chaperonin 10 Kd subunit Cpn10 PF00166.16 AIN99176.1 - 1.8e-22 79.0 0.1 2e-22 78.8 0.1 1.0 1 0 0 1 1 1 1 Chaperonin 10 Kd subunit Pyr_redox_3 PF13738.1 AIN99177.1 - 0.054 13.5 0.0 2.5 8.1 0.0 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Thioredoxin PF00085.15 AIN99178.1 - 1.6e-23 82.3 0.0 4.2e-11 42.4 0.0 2.3 2 0 0 2 2 2 2 Thioredoxin ERp29 PF07749.7 AIN99178.1 - 2.7e-20 72.8 0.0 6.1e-20 71.6 0.0 1.7 1 0 0 1 1 1 1 Endoplasmic reticulum protein ERp29, C-terminal domain HyaE PF07449.6 AIN99178.1 - 0.00023 20.9 0.0 0.52 10.2 0.0 2.5 2 0 0 2 2 2 2 Hydrogenase-1 expression protein HyaE Thioredoxin_6 PF13848.1 AIN99178.1 - 0.00028 20.7 0.9 0.023 14.5 0.5 2.4 1 1 1 2 2 2 1 Thioredoxin-like domain NPP1 PF05630.6 AIN99178.1 - 0.11 12.2 0.0 0.17 11.6 0.0 1.3 1 0 0 1 1 1 0 Necrosis inducing protein (NPP1) Thioredoxin PF00085.15 AIN99179.1 - 6.9e-20 70.6 0.0 9.1e-20 70.2 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.1 AIN99179.1 - 1.1e-06 28.6 0.1 0.0028 17.7 0.0 2.3 1 1 1 2 2 2 2 Thioredoxin-like Thioredoxin_2 PF13098.1 AIN99179.1 - 0.00012 22.2 0.1 0.0019 18.3 0.0 2.1 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_7 PF13899.1 AIN99179.1 - 0.0092 15.9 0.0 0.021 14.8 0.0 1.6 1 1 0 1 1 1 1 Thioredoxin-like DUF2012 PF09430.5 AIN99180.1 - 5e-34 116.7 0.1 6.7e-34 116.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2012) CarboxypepD_reg PF13620.1 AIN99180.1 - 0.00032 20.7 0.1 0.00056 19.9 0.1 1.4 1 0 0 1 1 1 1 Carboxypeptidase regulatory-like domain SNARE PF05739.14 AIN99181.1 - 7.4e-09 35.1 3.6 7.4e-09 35.1 2.5 2.6 4 0 0 4 4 4 1 SNARE domain Syntaxin-6_N PF09177.6 AIN99181.1 - 8.3e-06 26.1 4.6 1.2e-05 25.6 0.1 2.6 1 1 0 2 2 2 1 Syntaxin 6, N-terminal Laminin_II PF06009.7 AIN99181.1 - 0.054 13.2 3.1 0.3 10.8 0.1 2.4 2 1 0 2 2 2 0 Laminin Domain II PGM_PMM_II PF02879.11 AIN99181.1 - 0.059 13.7 0.2 1.3 9.3 0.0 2.3 2 0 0 2 2 2 0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II MCPsignal PF00015.16 AIN99181.1 - 0.097 12.1 6.6 1.2 8.6 0.3 2.3 1 1 1 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain PG_binding_1 PF01471.13 AIN99181.1 - 0.13 12.3 1.0 0.67 9.9 0.2 2.3 2 0 0 2 2 2 0 Putative peptidoglycan binding domain DivIVA PF05103.8 AIN99181.1 - 0.83 9.7 9.3 1.4 8.9 4.0 2.5 1 1 1 2 2 2 0 DivIVA protein EMP24_GP25L PF01105.19 AIN99181.1 - 1.9 8.1 4.6 0.88 9.2 0.2 2.2 2 0 0 2 2 2 0 emp24/gp25L/p24 family/GOLD Snapin_Pallidin PF14712.1 AIN99181.1 - 2.9 8.2 8.9 2.8 8.3 1.2 2.9 2 1 0 2 2 2 0 Snapin/Pallidin DUF2951 PF11166.3 AIN99181.1 - 3.7 7.4 8.0 0.64 9.9 2.1 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2951) COG2 PF06148.6 AIN99181.1 - 8.6 6.2 7.2 4.4 7.1 0.4 2.7 1 1 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Pentapeptide_4 PF13599.1 AIN99182.1 - 1e-07 31.6 8.4 1.7e-07 30.8 0.6 3.1 2 1 0 2 2 2 1 Pentapeptide repeats (9 copies) Pentapeptide_3 PF13576.1 AIN99182.1 - 1.5e-05 24.7 10.9 0.00082 19.2 1.0 3.9 2 1 1 3 3 3 3 Pentapeptide repeats (9 copies) Pentapeptide PF00805.17 AIN99182.1 - 2e-05 23.6 1.1 0.00019 20.5 0.0 3.0 4 0 0 4 4 4 1 Pentapeptide repeats (8 copies) DAGK_cat PF00781.19 AIN99183.1 - 1.7e-11 43.6 0.1 1.4e-09 37.4 0.0 2.7 3 0 0 3 3 3 2 Diacylglycerol kinase catalytic domain zf-RING_UBOX PF13445.1 AIN99185.1 - 0.018 14.7 0.5 0.044 13.5 0.0 1.8 2 0 0 2 2 2 0 RING-type zinc-finger RCC1 PF00415.13 AIN99186.1 - 7.6e-74 243.7 47.0 1.1e-16 60.7 0.5 12.4 11 2 0 11 11 11 11 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 AIN99186.1 - 9.7e-38 127.0 80.1 1.1e-06 28.0 0.0 12.1 12 0 0 12 12 12 10 Regulator of chromosome condensation (RCC1) repeat CBM_X PF06204.6 AIN99186.1 - 0.077 12.4 9.0 28 4.2 0.1 5.5 5 0 0 5 5 5 0 Putative carbohydrate binding domain Methyltransf_9 PF08003.6 AIN99186.1 - 0.16 10.5 0.1 6.9 5.2 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1698) Peptidase_C25_C PF03785.9 AIN99186.1 - 0.19 11.5 1.7 27 4.6 0.0 4.5 4 1 1 5 5 5 0 Peptidase family C25, C terminal ig-like domain RCC1 PF00415.13 AIN99187.1 - 9.2e-59 195.4 38.5 6.6e-12 45.4 0.3 12.8 12 2 0 12 12 12 10 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 AIN99187.1 - 3.7e-31 106.0 64.7 1.1e-05 24.8 0.6 12.3 12 0 0 12 12 12 9 Regulator of chromosome condensation (RCC1) repeat RRM_1 PF00076.17 AIN99188.1 - 1.4e-11 43.8 0.0 2e-11 43.3 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 AIN99188.1 - 9.4e-10 38.3 0.0 1.4e-09 37.7 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 AIN99188.1 - 0.001 18.8 0.1 0.0015 18.3 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 AIN99190.1 - 8.3e-06 25.3 0.0 0.00011 21.6 0.0 2.1 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 AIN99190.1 - 2.6e-05 24.1 0.0 3.7e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 AIN99190.1 - 0.083 12.7 0.0 0.13 12.0 0.0 1.2 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) GSHPx PF00255.14 AIN99192.1 - 4.3e-23 80.7 0.1 5.9e-23 80.2 0.1 1.2 1 0 0 1 1 1 1 Glutathione peroxidase GSHPx PF00255.14 AIN99193.1 - 4.4e-40 135.4 0.6 5.5e-40 135.0 0.4 1.1 1 0 0 1 1 1 1 Glutathione peroxidase AhpC-TSA PF00578.16 AIN99193.1 - 4.3e-06 26.4 0.1 8.3e-06 25.4 0.0 1.5 2 0 0 2 2 2 1 AhpC/TSA family Redoxin PF08534.5 AIN99193.1 - 7.6e-05 22.2 0.0 0.0012 18.4 0.0 2.0 2 0 0 2 2 2 1 Redoxin GSHPx PF00255.14 AIN99194.1 - 3.7e-40 135.6 0.6 4.6e-40 135.3 0.4 1.1 1 0 0 1 1 1 1 Glutathione peroxidase AhpC-TSA PF00578.16 AIN99194.1 - 5.1e-06 26.1 0.1 1e-05 25.1 0.1 1.5 2 0 0 2 2 2 1 AhpC/TSA family Redoxin PF08534.5 AIN99194.1 - 0.00015 21.3 0.0 0.0023 17.4 0.0 2.0 2 0 0 2 2 2 1 Redoxin AsnA PF03590.10 AIN99195.1 - 4.3e-93 311.2 0.0 7.3e-90 300.6 0.0 2.1 2 0 0 2 2 2 2 Aspartate-ammonia ligase tRNA-synt_2 PF00152.15 AIN99195.1 - 0.00014 20.7 0.1 0.021 13.6 0.0 2.4 2 1 0 2 2 2 2 tRNA synthetases class II (D, K and N) Nuc-transf PF10127.4 AIN99197.1 - 0.011 15.0 0.0 0.021 14.1 0.0 1.5 1 0 0 1 1 1 0 Predicted nucleotidyltransferase IF3_N PF05198.11 AIN99197.1 - 0.023 14.6 0.1 0.049 13.5 0.1 1.6 1 0 0 1 1 1 0 Translation initiation factor IF-3, N-terminal domain Exo_endo_phos PF03372.18 AIN99198.1 - 3.7e-10 40.1 0.1 6.6e-10 39.3 0.0 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family XRN_N PF03159.13 AIN99198.1 - 0.12 11.7 0.0 0.23 10.8 0.0 1.4 1 0 0 1 1 1 0 XRN 5'-3' exonuclease N-terminus zf-NADH-PPase PF09297.6 AIN99199.1 - 7 6.2 7.8 32 4.1 0.1 3.8 3 0 0 3 3 3 0 NADH pyrophosphatase zinc ribbon domain Ribosomal_S9 PF00380.14 AIN99200.1 - 3.6e-29 101.4 0.8 4.2e-29 101.2 0.5 1.0 1 0 0 1 1 1 1 Ribosomal protein S9/S16 HSP70 PF00012.15 AIN99201.1 - 1.4e-75 254.4 0.0 1.3e-38 132.3 0.0 2.4 2 0 0 2 2 2 2 Hsp70 protein MreB_Mbl PF06723.8 AIN99201.1 - 0.00018 20.2 0.0 0.18 10.3 0.0 3.1 2 1 1 3 3 3 2 MreB/Mbl protein OGFr_N PF04664.8 AIN99202.1 - 2.5e-05 23.6 0.1 0.029 13.6 0.0 2.3 2 0 0 2 2 2 2 Opioid growth factor receptor (OGFr) conserved region DNA_pol3_delt_C PF14840.1 AIN99202.1 - 0.073 13.1 0.0 0.13 12.3 0.0 1.4 1 0 0 1 1 1 0 Processivity clamp loader gamma complex DNA pol III C-term IstB_IS21 PF01695.12 AIN99204.1 - 8.5e-06 25.2 0.5 0.0017 17.7 0.1 3.1 3 0 0 3 3 3 1 IstB-like ATP binding protein PIF1 PF05970.9 AIN99204.1 - 2.2e-05 23.5 0.0 4e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 PIF1-like helicase SRP54 PF00448.17 AIN99204.1 - 0.0054 16.2 0.0 0.01 15.2 0.0 1.3 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain Bac_DnaA PF00308.13 AIN99204.1 - 0.13 11.8 0.0 0.3 10.6 0.0 1.6 1 0 0 1 1 1 0 Bacterial dnaA protein DUF815 PF05673.8 AIN99204.1 - 0.14 11.0 0.0 0.25 10.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Nitro_FeMo-Co PF02579.12 AIN99204.1 - 0.16 12.0 0.0 0.35 10.9 0.0 1.5 1 0 0 1 1 1 0 Dinitrogenase iron-molybdenum cofactor Sgf11 PF08209.6 AIN99204.1 - 0.25 10.6 5.3 4.8 6.5 0.1 3.3 3 0 0 3 3 3 0 Sgf11 (transcriptional regulation protein) DUF3395 PF11875.3 AIN99205.1 - 3e-45 153.5 0.0 5.5e-45 152.6 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3395) DnaJ PF00226.26 AIN99205.1 - 6.4e-16 57.8 0.1 1.1e-15 57.1 0.1 1.4 1 0 0 1 1 1 1 DnaJ domain Mcp5_PH PF12814.2 AIN99206.1 - 1e-24 86.7 2.5 2.3e-24 85.6 1.8 1.6 1 0 0 1 1 1 1 Meiotic cell cortex C-terminal pleckstrin homology NMD3 PF04981.8 AIN99208.1 - 1.5e-72 243.5 2.7 2e-72 243.1 1.9 1.2 1 0 0 1 1 1 1 NMD3 family DZR PF12773.2 AIN99208.1 - 3.6 7.4 10.7 1 9.2 2.3 2.7 2 1 0 2 2 2 0 Double zinc ribbon Pkinase PF00069.20 AIN99209.1 - 4.5e-33 114.4 0.0 1.3e-32 113.0 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AIN99209.1 - 3.1e-12 46.1 0.0 2.3e-06 26.8 0.0 2.6 2 0 0 2 2 2 2 Protein tyrosine kinase Pox_ser-thr_kin PF05445.6 AIN99209.1 - 0.089 11.5 0.0 0.13 10.9 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase PRKCSH-like PF12999.2 AIN99210.1 - 9.6e-38 129.4 1.5 1.7e-37 128.6 1.0 1.4 1 0 0 1 1 1 1 Glucosidase II beta subunit-like PRKCSH_1 PF13015.1 AIN99210.1 - 8.3e-18 64.3 0.0 1.8e-17 63.1 0.0 1.6 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein PRKCSH PF07915.8 AIN99210.1 - 1.7e-05 25.5 0.1 3.8e-05 24.4 0.1 1.6 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein XhlA PF10779.4 AIN99210.1 - 1.1 9.2 9.3 1.9 8.4 1.8 2.9 2 1 1 3 3 3 0 Haemolysin XhlA DUF3283 PF11686.3 AIN99211.1 - 0.089 12.6 0.0 1.7 8.4 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3283) DUF2682 PF10909.3 AIN99212.1 - 0.088 13.0 0.0 0.1 12.8 0.0 1.2 1 1 0 1 1 1 0 Protein of unknown function (DUF2682) Dynein_heavy PF03028.10 AIN99213.1 - 8e-195 648.9 0.0 3.5e-194 646.8 0.0 2.0 2 0 0 2 2 2 1 Dynein heavy chain and region D6 of dynein motor DHC_N2 PF08393.8 AIN99213.1 - 3.5e-121 404.5 5.5 3.5e-121 404.5 3.8 2.8 3 0 0 3 3 3 1 Dynein heavy chain, N-terminal region 2 AAA_6 PF12774.2 AIN99213.1 - 1.2e-94 316.1 0.0 2.6e-94 315.0 0.0 1.6 1 0 0 1 1 1 1 Hydrolytic ATP binding site of dynein motor region D1 AAA_8 PF12780.2 AIN99213.1 - 1.2e-65 221.1 0.1 2.6e-65 220.0 0.1 1.6 1 0 0 1 1 1 1 P-loop containing dynein motor region D4 AAA_9 PF12781.2 AIN99213.1 - 6.4e-57 192.0 2.8 1.1e-56 191.2 0.2 2.5 2 0 0 2 2 2 1 ATP-binding dynein motor region D5 MT PF12777.2 AIN99213.1 - 1.1e-51 175.6 6.0 2.4e-51 174.5 4.2 1.5 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_7 PF12775.2 AIN99213.1 - 1.1e-34 119.7 0.0 7.4e-34 117.0 0.0 2.2 2 0 0 2 2 2 1 P-loop containing dynein motor region D3 AAA_5 PF07728.9 AIN99213.1 - 1.1e-25 90.0 0.0 9.6e-07 28.6 0.0 5.7 4 1 0 4 4 4 4 AAA domain (dynein-related subfamily) AAA PF00004.24 AIN99213.1 - 4.1e-06 27.0 0.0 1.6 8.9 0.0 5.0 4 0 0 4 4 4 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 AIN99213.1 - 4.7e-06 26.7 9.8 1.4 8.8 0.0 7.5 5 2 2 7 7 7 2 AAA ATPase domain AAA_22 PF13401.1 AIN99213.1 - 0.00092 19.3 6.2 5.8 7.0 0.0 5.9 7 0 0 7 7 7 2 AAA domain AAA_17 PF13207.1 AIN99213.1 - 0.0012 19.5 0.1 10 6.9 0.0 5.5 6 0 0 6 6 5 0 AAA domain FtsK_SpoIIIE PF01580.13 AIN99213.1 - 0.0021 17.5 7.3 0.0033 16.9 0.1 3.8 4 0 0 4 4 4 1 FtsK/SpoIIIE family RNA_helicase PF00910.17 AIN99213.1 - 0.0091 16.1 0.0 3.6 7.7 0.0 4.3 4 0 0 4 4 4 1 RNA helicase AAA_19 PF13245.1 AIN99213.1 - 0.081 12.6 7.2 2.9 7.7 0.0 4.3 4 0 0 4 4 3 0 Part of AAA domain MobB PF03205.9 AIN99213.1 - 0.14 11.8 0.6 18 5.0 0.0 3.5 3 0 0 3 3 3 0 Molybdopterin guanine dinucleotide synthesis protein B Aldo_ket_red PF00248.16 AIN99214.1 - 3.8e-06 25.9 0.0 0.071 11.9 0.0 2.6 3 0 0 3 3 3 2 Aldo/keto reductase family Peptidase_M28 PF04389.12 AIN99215.1 - 0.00014 21.6 0.1 0.00045 20.0 0.0 1.8 2 0 0 2 2 2 1 Peptidase family M28 Arfaptin PF06456.8 AIN99215.1 - 0.036 13.4 1.0 0.058 12.7 0.2 1.7 2 0 0 2 2 2 0 Arfaptin-like domain Fer2 PF00111.22 AIN99216.1 - 1.5e-12 47.0 1.0 2.4e-12 46.4 0.7 1.3 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain RRM_1 PF00076.17 AIN99217.1 - 1.1e-07 31.4 0.0 1.9e-07 30.6 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 AIN99217.1 - 5.5e-06 26.2 0.0 9.3e-06 25.5 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 AIN99217.1 - 0.00021 21.0 0.0 0.00034 20.4 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Btz PF09405.5 AIN99217.1 - 0.12 12.4 0.3 0.22 11.5 0.0 1.6 2 0 0 2 2 2 0 CASC3/Barentsz eIF4AIII binding TROVE PF05731.6 AIN99222.1 - 1.2e-45 155.9 0.2 2e-30 105.8 0.1 2.4 2 0 0 2 2 2 2 TROVE domain WD40 PF00400.27 AIN99222.1 - 8.8e-16 57.1 38.3 0.0012 18.6 0.1 11.6 12 0 0 12 12 12 4 WD domain, G-beta repeat DUF4062 PF13271.1 AIN99222.1 - 0.0015 18.5 0.0 0.0059 16.5 0.0 2.0 1 1 0 1 1 1 1 Domain of unknown function (DUF4062) Ax_dynein_light PF10211.4 AIN99223.1 - 6.9e-50 169.5 3.0 1e-49 168.9 2.1 1.2 1 0 0 1 1 1 1 Axonemal dynein light chain IncA PF04156.9 AIN99223.1 - 0.13 11.7 4.9 0.25 10.9 3.4 1.5 1 0 0 1 1 1 0 IncA protein TRAPP PF04051.11 AIN99225.1 - 0.12 11.8 0.0 0.21 11.1 0.0 1.4 1 0 0 1 1 1 0 Transport protein particle (TRAPP) component PseudoU_synth_2 PF00849.17 AIN99227.1 - 5.4e-15 55.5 0.0 3e-07 30.4 0.0 3.6 2 2 0 2 2 2 2 RNA pseudouridylate synthase zf-RING_2 PF13639.1 AIN99228.1 - 4.7e-07 29.5 3.6 4.7e-07 29.5 2.5 2.9 3 0 0 3 3 3 2 Ring finger domain zf-C3HC4_3 PF13920.1 AIN99228.1 - 3.2e-06 26.7 2.1 3.2e-06 26.7 1.5 3.0 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 AIN99228.1 - 7e-05 22.7 3.6 7e-05 22.7 2.5 3.0 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 AIN99228.1 - 0.0032 17.1 1.7 0.0032 17.1 1.2 3.1 3 0 0 3 3 3 1 zinc-RING finger domain zf-C3HC4 PF00097.20 AIN99228.1 - 0.0039 16.8 2.1 0.0039 16.8 1.5 3.0 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) Baculo_IE-1 PF05290.6 AIN99228.1 - 0.018 14.7 0.5 0.046 13.4 0.3 1.6 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) zf-rbx1 PF12678.2 AIN99228.1 - 0.038 14.0 4.2 0.044 13.8 0.4 2.4 2 0 0 2 2 2 0 RING-H2 zinc finger Prefoldin_2 PF01920.15 AIN99228.1 - 0.058 13.1 0.6 0.14 11.8 0.4 1.6 1 0 0 1 1 1 0 Prefoldin subunit DivIVA PF05103.8 AIN99228.1 - 1.6 8.7 5.4 3.1 7.8 3.8 1.4 1 0 0 1 1 1 0 DivIVA protein DUF2681 PF10883.3 AIN99228.1 - 1.8 8.8 3.9 6.7 7.0 0.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2681) Beta_helix PF13229.1 AIN99229.1 - 2.6e-05 24.0 0.0 0.085 12.6 0.0 2.6 2 0 0 2 2 2 2 Right handed beta helix region DUF3613 PF12266.3 AIN99229.1 - 0.21 11.1 0.1 0.21 11.1 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3613) DnaJ PF00226.26 AIN99231.1 - 1.4e-20 72.7 0.2 2.8e-20 71.7 0.1 1.5 1 0 0 1 1 1 1 DnaJ domain DnaJ-X PF14308.1 AIN99231.1 - 1.9e-05 24.0 0.0 5.7e-05 22.4 0.0 1.9 1 1 0 1 1 1 1 X-domain of DnaJ-containing Aldo_ket_red PF00248.16 AIN99232.1 - 1.3e-34 119.3 0.0 2e-28 99.0 0.0 2.2 2 0 0 2 2 2 2 Aldo/keto reductase family DUF2236 PF09995.4 AIN99232.1 - 0.029 13.6 0.0 0.05 12.8 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2236) T2SM PF04612.7 AIN99232.1 - 0.11 12.2 0.1 0.24 11.1 0.0 1.5 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein M LRR_4 PF12799.2 AIN99233.1 - 1.1e-14 53.6 0.2 3.4e-06 26.5 0.1 4.4 3 1 1 4 4 4 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 AIN99233.1 - 3.7e-12 45.8 4.6 0.00044 19.9 1.0 3.8 3 1 0 4 4 4 3 Leucine rich repeat LRR_1 PF00560.28 AIN99233.1 - 2.4e-07 29.8 12.2 1.1 9.5 0.2 6.7 6 1 1 7 7 7 3 Leucine Rich Repeat LRR_7 PF13504.1 AIN99233.1 - 5.6e-06 25.7 7.0 4.6 7.8 0.0 5.9 5 1 0 5 5 5 3 Leucine rich repeat LRR_6 PF13516.1 AIN99233.1 - 2.9e-05 23.6 3.1 1.1 9.5 0.1 4.3 3 1 1 4 4 4 3 Leucine Rich repeat DUF1675 PF07897.6 AIN99233.1 - 5.7 6.7 11.6 3.6 7.3 5.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1675) PTCB-BRCT PF12738.2 AIN99234.1 - 3.5e-07 29.9 0.1 0.074 12.9 0.0 4.1 4 0 0 4 4 4 3 twin BRCT domain BRCT PF00533.21 AIN99234.1 - 0.00041 20.4 0.0 21 5.3 0.0 4.5 4 0 0 4 4 4 3 BRCA1 C Terminus (BRCT) domain HSP70 PF00012.15 AIN99235.1 - 1.2e-251 835.9 6.6 1.3e-251 835.7 4.5 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 AIN99235.1 - 8.5e-19 67.3 0.5 4.8e-17 61.5 0.1 2.4 2 0 0 2 2 2 2 MreB/Mbl protein FtsA PF14450.1 AIN99235.1 - 0.0022 17.7 3.4 0.023 14.5 0.4 3.6 2 1 0 2 2 2 1 Cell division protein FtsA Hydantoinase_A PF01968.13 AIN99235.1 - 0.0064 15.6 2.2 0.015 14.3 0.1 2.7 3 0 0 3 3 3 1 Hydantoinase/oxoprolinase HA PF03457.9 AIN99236.1 - 0.075 13.1 0.2 0.3 11.2 0.0 2.1 2 0 0 2 2 2 0 Helicase associated domain FYVE PF01363.16 AIN99237.1 - 1.1e-13 50.8 3.4 1.1e-13 50.8 2.4 2.7 2 0 0 2 2 2 1 FYVE zinc finger DnaJ PF00226.26 AIN99238.1 - 1.3e-22 79.2 0.1 2.7e-22 78.2 0.1 1.6 1 0 0 1 1 1 1 DnaJ domain DnaJ-X PF14308.1 AIN99238.1 - 2e-10 40.3 0.0 9.7e-05 21.7 0.1 2.6 1 1 1 2 2 2 2 X-domain of DnaJ-containing Cupin_8 PF13621.1 AIN99240.1 - 1.8e-53 181.6 0.0 1.1e-52 179.0 0.0 1.9 1 1 0 1 1 1 1 Cupin-like domain DUF2890 PF11081.3 AIN99240.1 - 0.19 11.7 0.1 0.19 11.7 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2890) Med3 PF11593.3 AIN99242.1 - 0.1 11.8 0.6 0.17 11.0 0.4 1.3 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal PgaD PF13994.1 AIN99242.1 - 3.8 7.0 6.7 0.25 10.8 0.3 2.2 2 0 0 2 2 2 0 PgaD-like protein DNA_ligase_OB_2 PF14743.1 AIN99245.1 - 6.1e-21 73.8 0.1 1.1e-20 73.0 0.1 1.5 1 0 0 1 1 1 1 DNA ligase OB-like domain DUF4379 PF14311.1 AIN99245.1 - 1.6e-14 53.4 3.4 4.1e-14 52.1 2.4 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4379) DNA_ligase_A_M PF01068.16 AIN99245.1 - 1.1e-11 44.4 0.0 6.8e-07 28.8 0.0 2.5 2 0 0 2 2 2 2 ATP dependent DNA ligase domain mRNA_cap_enzyme PF01331.14 AIN99245.1 - 0.0091 15.7 0.0 0.23 11.1 0.0 2.3 2 0 0 2 2 2 1 mRNA capping enzyme, catalytic domain PhnA_Zn_Ribbon PF08274.7 AIN99245.1 - 0.013 15.2 2.9 0.65 9.8 1.0 2.4 2 0 0 2 2 2 0 PhnA Zinc-Ribbon zf-ribbon_3 PF13248.1 AIN99245.1 - 0.17 11.1 1.2 3.2 7.0 0.1 2.3 2 0 0 2 2 2 0 zinc-ribbon domain zf-HYPF PF07503.7 AIN99245.1 - 0.2 11.0 2.4 0.38 10.2 1.7 1.5 1 0 0 1 1 1 0 HypF finger DNA_ligase_A_M PF01068.16 AIN99246.1 - 2.1e-22 79.5 0.0 6.2e-22 77.9 0.0 1.8 1 1 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_OB_2 PF14743.1 AIN99246.1 - 4.7e-16 58.2 0.0 8.6e-16 57.3 0.0 1.5 1 0 0 1 1 1 1 DNA ligase OB-like domain Zn-ribbon_8 PF09723.5 AIN99246.1 - 0.0045 16.9 0.5 0.013 15.3 0.3 1.8 1 0 0 1 1 1 1 Zinc ribbon domain DUF4379 PF14311.1 AIN99246.1 - 0.043 13.6 6.4 0.092 12.5 4.4 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4379) Thioredoxin PF00085.15 AIN99247.1 - 0.019 14.6 0.0 0.17 11.6 0.0 2.3 2 0 0 2 2 2 0 Thioredoxin MMR_HSR1 PF01926.18 AIN99248.1 - 1.5e-15 57.1 0.0 8.7e-13 48.2 0.0 2.4 2 0 0 2 2 2 2 50S ribosome-binding GTPase FeoB_N PF02421.13 AIN99248.1 - 2.9e-06 26.6 0.0 0.00033 19.9 0.0 2.2 2 0 0 2 2 2 2 Ferrous iron transport protein B GTP_EFTU PF00009.22 AIN99248.1 - 0.00026 20.4 0.0 1.2 8.5 0.0 3.1 2 1 0 2 2 2 2 Elongation factor Tu GTP binding domain Dynamin_N PF00350.18 AIN99248.1 - 0.0011 18.7 1.3 0.035 13.9 0.2 2.7 1 1 1 2 2 2 1 Dynamin family DUF258 PF03193.11 AIN99248.1 - 0.0042 16.2 0.0 0.0085 15.2 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Prefoldin PF02996.12 AIN99249.1 - 1e-25 89.6 1.8 1.4e-25 89.2 0.9 1.5 1 1 0 1 1 1 1 Prefoldin subunit DUF3847 PF12958.2 AIN99249.1 - 0.061 13.0 1.7 7.6 6.3 0.6 2.8 3 1 0 3 3 3 0 Protein of unknown function (DUF3847) Prefoldin_2 PF01920.15 AIN99249.1 - 0.069 12.9 4.0 1.6 8.5 0.3 2.4 2 1 0 2 2 2 0 Prefoldin subunit DUF972 PF06156.8 AIN99249.1 - 0.24 11.7 5.7 8 6.8 2.5 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF972) IncA PF04156.9 AIN99249.1 - 0.57 9.7 4.3 5.8 6.4 0.6 2.1 2 0 0 2 2 2 0 IncA protein WD40 PF00400.27 AIN99251.1 - 3.7e-27 93.1 16.8 3.1e-07 30.0 0.1 7.0 7 0 0 7 7 7 6 WD domain, G-beta repeat WWE PF02825.15 AIN99251.1 - 2.1e-07 30.2 0.4 5.4e-07 28.9 0.3 1.7 1 1 0 1 1 1 1 WWE domain DnaJ PF00226.26 AIN99252.1 - 2.2e-19 68.9 0.3 2.2e-19 68.9 0.2 1.9 2 0 0 2 2 2 1 DnaJ domain DUF3180 PF11377.3 AIN99252.1 - 0.029 14.2 5.5 0.031 14.1 0.4 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF3180) MORN PF02493.15 AIN99253.1 - 7.6e-41 135.4 129.9 0.0001 21.8 0.3 24.4 26 0 0 26 26 26 19 MORN repeat FYVE PF01363.16 AIN99253.1 - 4e-26 90.7 15.7 9.4e-19 67.0 3.5 2.7 2 0 0 2 2 2 2 FYVE zinc finger Cyt-b5 PF00173.23 AIN99254.1 - 4.2e-19 68.1 0.0 8.7e-19 67.1 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain ESR1_C PF12743.2 AIN99255.1 - 0.032 13.7 1.6 0.065 12.7 0.2 2.3 2 0 0 2 2 2 0 Oestrogen-type nuclear receptor final C-terminal DUF2668 PF10873.3 AIN99257.1 - 0.0028 17.8 4.4 0.004 17.3 0.0 2.8 3 0 0 3 3 3 1 Protein of unknown function (DUF2668) Shisa PF13908.1 AIN99257.1 - 0.0078 16.4 0.7 0.081 13.0 0.0 2.7 3 0 0 3 3 3 1 Wnt and FGF inhibitory regulator Prenyltrans PF00432.16 AIN99258.1 - 6.1e-23 80.0 14.1 4.5e-05 22.9 0.1 5.9 5 0 0 5 5 5 5 Prenyltransferase and squalene oxidase repeat Prenyltrans_2 PF13249.1 AIN99258.1 - 7.1e-23 81.1 1.8 1.6e-16 60.6 0.0 4.8 4 1 1 5 5 5 3 Prenyltransferase-like Prenyltrans_1 PF13243.1 AIN99258.1 - 3.3e-06 27.0 0.1 0.0018 18.3 0.0 2.8 2 0 0 2 2 2 2 Prenyltransferase-like COG7 PF10191.4 AIN99259.1 - 5.6e-10 37.8 14.5 0.002 16.1 1.1 5.1 5 0 0 5 5 5 5 Golgi complex component 7 (COG7) zf-ZPR1 PF03367.8 AIN99259.1 - 0.0019 17.3 3.0 1.1 8.3 0.2 3.3 3 0 0 3 3 3 2 ZPR1 zinc-finger domain PhoD PF09423.5 AIN99260.1 - 0.0027 16.3 0.0 0.08 11.5 0.0 2.3 2 1 0 2 2 2 2 PhoD-like phosphatase Abhydrolase_6 PF12697.2 AIN99263.1 - 5.2e-21 75.5 1.9 8.4e-21 74.8 1.3 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 AIN99263.1 - 3.4e-06 26.8 0.0 1.4e-05 24.8 0.0 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 AIN99263.1 - 0.0017 17.9 0.6 2.2 7.7 0.1 3.2 2 1 0 2 2 2 2 alpha/beta hydrolase fold DUF915 PF06028.6 AIN99263.1 - 0.0026 16.8 0.0 0.0078 15.3 0.0 1.7 2 0 0 2 2 2 1 Alpha/beta hydrolase of unknown function (DUF915) Hydrolase_4 PF12146.3 AIN99263.1 - 0.07 12.9 0.0 3.2 7.6 0.0 2.8 2 0 0 2 2 2 0 Putative lysophospholipase RRM_1 PF00076.17 AIN99264.1 - 1.1e-16 60.1 0.0 1.8e-16 59.5 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 AIN99264.1 - 1.4e-14 53.7 0.0 2.4e-14 53.0 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 AIN99264.1 - 1.1e-11 44.4 0.0 1.8e-11 43.7 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Glutaredoxin PF00462.19 AIN99265.1 - 5.4e-07 29.4 0.0 1.3e-06 28.3 0.0 1.6 1 0 0 1 1 1 1 Glutaredoxin GST_N_3 PF13417.1 AIN99265.1 - 1.2e-05 25.4 0.0 2.8e-05 24.2 0.0 1.7 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 AIN99265.1 - 0.017 15.1 0.0 0.079 12.9 0.0 2.2 2 1 0 2 2 2 0 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 AIN99265.1 - 0.025 15.0 0.0 0.06 13.8 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain DUF836 PF05768.9 AIN99265.1 - 0.062 13.5 0.0 0.11 12.8 0.0 1.4 1 0 0 1 1 1 0 Glutaredoxin-like domain (DUF836) RVT_1 PF00078.22 AIN99265.1 - 0.14 11.5 0.0 0.42 9.9 0.0 1.7 2 0 0 2 2 2 0 Reverse transcriptase (RNA-dependent DNA polymerase) DUF3918 PF13056.1 AIN99265.1 - 0.25 10.6 0.9 0.85 8.9 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3918) 3HCDH_N PF02737.13 AIN99266.1 - 1e-49 168.6 3.3 1.8e-49 167.8 2.3 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ECH PF00378.15 AIN99266.1 - 1e-44 152.5 0.1 2.1e-44 151.4 0.1 1.5 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family 3HCDH PF00725.17 AIN99266.1 - 3.9e-33 113.7 0.1 7.4e-23 80.7 0.0 3.0 3 0 0 3 3 3 2 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain NAD_binding_2 PF03446.10 AIN99266.1 - 0.00015 21.6 2.2 0.0002 21.2 0.3 2.1 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase Shikimate_DH PF01488.15 AIN99266.1 - 0.0089 16.1 1.9 1.3 9.0 0.3 2.5 2 0 0 2 2 2 2 Shikimate / quinate 5-dehydrogenase F420_oxidored PF03807.12 AIN99266.1 - 0.04 14.3 0.8 0.2 12.1 0.6 2.3 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent SNF2_N PF00176.18 AIN99267.1 - 4e-30 104.6 0.1 1e-20 73.7 0.0 3.1 3 0 0 3 3 3 3 SNF2 family N-terminal domain zf-RING_2 PF13639.1 AIN99267.1 - 2.3e-08 33.7 8.0 6.2e-08 32.3 3.5 2.9 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.1 AIN99267.1 - 1.6e-07 31.2 6.5 1.6e-07 31.2 4.5 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 AIN99267.1 - 9.1e-07 28.4 6.7 9.1e-07 28.4 4.7 2.9 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 AIN99267.1 - 9.7e-07 28.3 5.5 3.4e-06 26.6 3.8 2.0 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Helicase_C PF00271.26 AIN99267.1 - 2.2e-06 27.4 0.0 4.9e-06 26.3 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-RING_5 PF14634.1 AIN99267.1 - 4.1e-05 23.2 5.1 4.1e-05 23.2 3.5 2.2 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 AIN99267.1 - 0.00034 20.4 6.1 0.00034 20.4 4.2 2.2 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 AIN99267.1 - 0.0019 17.8 3.2 0.0049 16.5 2.2 1.8 1 0 0 1 1 1 1 RING-type zinc-finger DEAD PF00270.24 AIN99267.1 - 0.0034 16.9 0.0 0.0071 15.8 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Peptidase_M3 PF01432.15 AIN99268.1 - 3.6e-116 388.9 0.0 1.4e-115 386.9 0.0 1.7 2 0 0 2 2 2 1 Peptidase family M3 Peptidase_M50B PF13398.1 AIN99268.1 - 0.032 13.6 0.5 0.065 12.5 0.3 1.5 1 0 0 1 1 1 0 Peptidase M50B-like PQQ_2 PF13360.1 AIN99269.1 - 0.00031 20.2 0.4 0.0013 18.2 0.0 2.1 3 0 0 3 3 3 1 PQQ-like domain WD40 PF00400.27 AIN99270.1 - 3.6e-20 71.0 3.2 0.0001 22.0 0.0 4.6 4 0 0 4 4 4 4 WD domain, G-beta repeat EF-hand_7 PF13499.1 AIN99270.1 - 3e-05 24.0 0.0 5.9e-05 23.1 0.0 1.5 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_8 PF13833.1 AIN99270.1 - 0.00011 21.7 0.1 0.00069 19.1 0.0 2.2 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.27 AIN99270.1 - 0.00011 21.2 0.0 0.0015 17.6 0.0 2.3 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.1 AIN99270.1 - 0.0024 17.5 0.0 0.14 12.1 0.0 2.5 2 0 0 2 2 2 1 EF-hand domain EF-hand_5 PF13202.1 AIN99270.1 - 0.1 12.0 0.0 0.25 10.7 0.0 1.6 1 0 0 1 1 1 0 EF hand PPK2 PF03976.9 AIN99270.1 - 0.1 11.8 0.0 0.16 11.1 0.0 1.3 1 0 0 1 1 1 0 Polyphosphate kinase 2 (PPK2) U-box PF04564.10 AIN99271.1 - 0.00048 20.0 0.0 0.00098 19.0 0.0 1.5 1 0 0 1 1 1 1 U-box domain Pro_dh PF01619.13 AIN99272.1 - 1.9e-55 188.0 0.5 2.7e-55 187.5 0.4 1.2 1 0 0 1 1 1 1 Proline dehydrogenase AP_endonuc_2 PF01261.19 AIN99272.1 - 0.0061 15.8 0.1 0.061 12.5 0.0 2.4 2 1 1 3 3 3 1 Xylose isomerase-like TIM barrel CTP_transf_1 PF01148.15 AIN99273.1 - 2.9e-61 207.3 21.5 3.7e-61 207.0 14.9 1.1 1 0 0 1 1 1 1 Cytidylyltransferase family Ribosomal_S28e PF01200.13 AIN99274.1 - 1.7e-29 101.3 2.5 2.1e-29 101.0 1.7 1.1 1 0 0 1 1 1 1 Ribosomal protein S28e GCD14_N PF14801.1 AIN99274.1 - 0.084 12.4 0.5 0.13 11.8 0.3 1.4 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit N-term Ribosomal_S28e PF01200.13 AIN99275.1 - 1.7e-29 101.3 2.5 2.1e-29 101.0 1.7 1.1 1 0 0 1 1 1 1 Ribosomal protein S28e GCD14_N PF14801.1 AIN99275.1 - 0.084 12.4 0.5 0.13 11.8 0.3 1.4 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit N-term MIT PF04212.13 AIN99276.1 - 0.0017 18.2 0.5 0.0044 16.8 0.1 1.9 2 0 0 2 2 2 1 MIT (microtubule interacting and transport) domain FliS PF02561.9 AIN99276.1 - 0.033 14.0 0.1 0.18 11.6 0.0 2.0 2 0 0 2 2 2 0 Flagellar protein FliS LRR_6 PF13516.1 AIN99277.1 - 8.4e-07 28.4 7.7 0.13 12.3 0.1 6.2 6 0 0 6 6 6 2 Leucine Rich repeat LRR_1 PF00560.28 AIN99277.1 - 4e-06 26.1 10.7 0.81 9.9 0.0 6.5 6 0 0 6 6 6 2 Leucine Rich Repeat LRR_4 PF12799.2 AIN99277.1 - 0.0031 17.0 6.3 0.96 9.1 0.2 4.4 4 2 0 4 4 4 2 Leucine Rich repeats (2 copies) DUF3124 PF11322.3 AIN99277.1 - 0.16 11.9 0.0 0.3 11.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3124) LRR_8 PF13855.1 AIN99277.1 - 0.24 11.1 6.8 15 5.3 0.0 4.9 4 2 0 4 4 4 0 Leucine rich repeat LRR_7 PF13504.1 AIN99277.1 - 0.73 10.2 15.8 9.4 6.9 0.0 6.5 7 0 0 7 7 7 0 Leucine rich repeat FA_desaturase PF00487.19 AIN99278.1 - 3.1e-24 85.8 24.9 5e-24 85.1 17.3 1.3 1 0 0 1 1 1 1 Fatty acid desaturase Lipid_DES PF08557.5 AIN99278.1 - 8.8e-15 53.6 0.8 1.8e-14 52.6 0.5 1.6 1 0 0 1 1 1 1 Sphingolipid Delta4-desaturase (DES) Pkinase PF00069.20 AIN99281.1 - 7.8e-58 195.6 0.0 1.4e-57 194.8 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AIN99281.1 - 2.1e-36 125.3 0.0 3.5e-36 124.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 AIN99281.1 - 1.2e-07 31.0 0.0 2.3e-05 23.5 0.0 2.2 2 0 0 2 2 2 2 Kinase-like PAS PF00989.19 AIN99281.1 - 2.3e-06 27.3 0.0 7.4e-06 25.7 0.0 1.8 2 0 0 2 2 2 1 PAS fold PAS_4 PF08448.5 AIN99281.1 - 4e-06 26.8 0.0 1.8e-05 24.7 0.0 2.1 2 0 0 2 2 2 1 PAS fold PAS_9 PF13426.1 AIN99281.1 - 6.2e-06 26.5 0.0 2.1e-05 24.8 0.0 1.9 1 0 0 1 1 1 1 PAS domain Kdo PF06293.9 AIN99281.1 - 7.1e-05 21.9 0.0 0.00029 19.9 0.0 2.0 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family PAS_10 PF13596.1 AIN99281.1 - 0.0019 18.4 0.0 0.0073 16.5 0.0 2.0 2 0 0 2 2 2 1 PAS domain PAS_8 PF13188.1 AIN99281.1 - 0.076 12.9 0.0 0.35 10.8 0.0 2.1 1 0 0 1 1 1 0 PAS domain APH PF01636.18 AIN99281.1 - 0.083 12.6 0.0 0.21 11.2 0.0 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family ANTAR PF03861.9 AIN99286.1 - 0.041 13.4 0.2 0.041 13.4 0.2 2.6 4 0 0 4 4 4 0 ANTAR domain NuA4 PF09340.5 AIN99287.1 - 2.2e-07 30.3 0.0 3.7e-06 26.4 0.0 2.2 2 0 0 2 2 2 1 Histone acetyltransferase subunit NuA4 HEAT PF02985.17 AIN99288.1 - 0.0032 17.4 0.3 2.2 8.6 0.0 4.7 3 0 0 3 3 3 1 HEAT repeat BP28CT PF08146.7 AIN99288.1 - 0.03 14.0 0.1 0.76 9.4 0.0 3.0 3 0 0 3 3 3 0 BP28CT (NUC211) domain HTH_6 PF01418.12 AIN99288.1 - 0.077 12.7 1.6 4.4 7.1 0.2 2.8 2 0 0 2 2 2 0 Helix-turn-helix domain, rpiR family DNA_binding_1 PF01035.15 AIN99289.1 - 4.7e-18 64.7 0.0 1e-17 63.6 0.0 1.6 1 0 0 1 1 1 1 6-O-methylguanine DNA methyltransferase, DNA binding domain SSI PF00720.12 AIN99289.1 - 0.025 14.5 0.5 0.052 13.4 0.4 1.5 1 0 0 1 1 1 0 Subtilisin inhibitor-like zf-C2H2_4 PF13894.1 AIN99290.1 - 0.0079 16.4 0.2 0.0079 16.4 0.2 3.4 3 1 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_6 PF13912.1 AIN99290.1 - 0.011 15.5 0.5 0.011 15.5 0.3 2.1 2 0 0 2 2 2 0 C2H2-type zinc finger zf-Di19 PF05605.7 AIN99290.1 - 0.059 13.4 0.1 0.059 13.4 0.1 2.2 2 1 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2 PF00096.21 AIN99290.1 - 0.46 10.9 0.1 0.24 11.8 1.5 3.2 3 0 0 3 3 3 0 Zinc finger, C2H2 type PBP1_TM PF14812.1 AIN99290.1 - 7 7.0 7.6 7.3 6.9 1.5 2.6 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal PilM PF07419.7 AIN99291.1 - 0.043 13.3 0.0 0.1 12.0 0.0 1.6 1 0 0 1 1 1 0 PilM Methyltransf_18 PF12847.2 AIN99293.1 - 0.061 13.9 0.3 0.43 11.1 0.1 2.4 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_31 PF13847.1 AIN99293.1 - 0.3 10.6 0.0 0.62 9.6 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain ELMO_CED12 PF04727.8 AIN99294.1 - 1.3e-43 148.5 0.1 1.8e-43 148.0 0.0 1.2 1 0 0 1 1 1 1 ELMO/CED-12 family DUF3038 PF11237.3 AIN99294.1 - 0.013 15.3 0.7 0.013 15.3 0.5 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3038) LRR_6 PF13516.1 AIN99296.1 - 2.9e-05 23.6 0.4 2.5 8.4 0.0 5.2 5 0 0 5 5 5 2 Leucine Rich repeat LRR_1 PF00560.28 AIN99296.1 - 0.043 13.8 2.5 17 5.9 0.0 4.9 6 0 0 6 6 6 0 Leucine Rich Repeat LRR_4 PF12799.2 AIN99296.1 - 0.054 13.1 0.9 54 3.5 0.0 4.5 5 2 0 5 5 5 0 Leucine Rich repeats (2 copies) LRR_7 PF13504.1 AIN99296.1 - 1.9 9.0 7.5 23 5.7 0.1 4.9 4 0 0 4 4 4 0 Leucine rich repeat DUF4460 PF14687.1 AIN99297.1 - 5.7e-09 35.7 0.2 1.4e-08 34.4 0.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4460) DUF4461 PF14688.1 AIN99297.1 - 0.022 14.1 6.7 0.017 14.4 1.5 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4461) DUF3741 PF12552.3 AIN99297.1 - 0.051 13.2 0.0 0.23 11.2 0.0 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3741) Sedlin_N PF04628.8 AIN99298.1 - 2.7e-06 27.2 0.0 9.9e-06 25.4 0.0 1.8 1 1 0 1 1 1 1 Sedlin, N-terminal conserved region L27 PF02828.11 AIN99298.1 - 0.15 11.7 0.0 0.32 10.7 0.0 1.5 1 0 0 1 1 1 0 L27 domain HEAT_2 PF13646.1 AIN99300.1 - 8.2e-29 99.7 9.2 4.1e-16 59.0 0.2 3.3 2 1 1 3 3 3 3 HEAT repeats HEAT_PBS PF03130.11 AIN99300.1 - 2.1e-17 61.7 13.8 0.00087 19.5 0.1 6.5 7 0 0 7 7 7 4 PBS lyase HEAT-like repeat HEAT_EZ PF13513.1 AIN99300.1 - 1.3e-08 35.0 6.6 0.00064 20.1 0.8 4.8 3 1 1 4 4 4 2 HEAT-like repeat HEAT PF02985.17 AIN99300.1 - 7.5e-07 28.7 2.4 0.021 14.8 0.0 4.9 4 1 0 5 5 5 2 HEAT repeat TRAM_LAG1_CLN8 PF03798.11 AIN99301.1 - 1.7e-17 63.6 16.1 1.7e-17 63.6 11.1 1.5 2 0 0 2 2 2 1 TLC domain 4HBT_2 PF13279.1 AIN99302.1 - 7.1e-11 42.6 0.0 1.6e-10 41.4 0.0 1.7 1 1 0 1 1 1 1 Thioesterase-like superfamily 4HBT PF03061.17 AIN99302.1 - 1.6e-09 37.7 0.0 2.4e-08 33.9 0.0 2.4 2 0 0 2 2 2 1 Thioesterase superfamily Acyl-ACP_TE PF01643.12 AIN99302.1 - 0.014 14.3 0.2 0.095 11.6 0.1 2.0 1 1 0 1 1 1 0 Acyl-ACP thioesterase MarR_2 PF12802.2 AIN99303.1 - 0.024 14.2 0.0 75 3.1 0.0 4.2 3 0 0 3 3 3 0 MarR family ABC_tran_2 PF12848.2 AIN99304.1 - 0.064 13.0 7.0 0.21 11.4 4.9 1.8 1 0 0 1 1 1 0 ABC transporter SCO1-SenC PF02630.9 AIN99305.1 - 3.8e-45 153.6 0.0 4.9e-45 153.2 0.0 1.1 1 0 0 1 1 1 1 SCO1/SenC AhpC-TSA PF00578.16 AIN99305.1 - 0.00018 21.1 0.0 0.00034 20.3 0.0 1.5 1 1 0 1 1 1 1 AhpC/TSA family Thioredoxin_8 PF13905.1 AIN99305.1 - 0.00061 19.8 0.0 0.0011 19.0 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin-like Methyltransf_23 PF13489.1 AIN99308.1 - 6.5e-15 55.2 0.0 1.1e-14 54.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 AIN99308.1 - 1e-14 55.0 0.0 1.9e-14 54.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 AIN99308.1 - 5.2e-13 48.8 0.0 4.5e-06 26.3 0.0 2.7 2 1 0 2 2 2 2 Methyltransferase domain Methyltransf_11 PF08241.7 AIN99308.1 - 1.3e-10 41.6 0.0 0.00081 19.8 0.0 2.5 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_12 PF08242.7 AIN99308.1 - 1e-09 38.7 0.0 1.3e-08 35.2 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 AIN99308.1 - 5.6e-07 29.8 0.0 2.4e-06 27.8 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain DREV PF05219.7 AIN99308.1 - 0.0014 17.6 0.0 0.0045 15.8 0.0 1.7 1 1 0 2 2 2 1 DREV methyltransferase Methyltransf_26 PF13659.1 AIN99308.1 - 0.0036 17.3 0.0 0.0071 16.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 AIN99308.1 - 0.0071 15.4 0.1 0.027 13.5 0.0 1.8 1 1 1 2 2 2 1 Mycolic acid cyclopropane synthetase Methyltransf_3 PF01596.12 AIN99308.1 - 0.015 14.3 0.0 0.032 13.2 0.0 1.6 1 0 0 1 1 1 0 O-methyltransferase STOP PF05217.7 AIN99308.1 - 0.11 12.1 1.0 0.18 11.5 0.7 1.2 1 0 0 1 1 1 0 STOP protein PHD PF00628.24 AIN99309.1 - 0.0019 17.8 7.0 0.0037 16.9 4.9 1.5 1 0 0 1 1 1 1 PHD-finger HEAT PF02985.17 AIN99311.1 - 0.36 11.0 2.6 0.82 9.9 0.0 3.1 3 0 0 3 3 3 0 HEAT repeat PQ-loop PF04193.9 AIN99312.1 - 4.9e-19 67.6 0.2 1e-12 47.3 0.0 2.6 2 0 0 2 2 2 2 PQ loop repeat Pkinase PF00069.20 AIN99314.1 - 1e-13 51.0 0.1 5.6e-11 42.0 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 AIN99314.1 - 8e-08 31.6 0.1 0.00076 18.6 0.0 3.0 3 0 0 3 3 3 2 Protein tyrosine kinase Peptidase_C48 PF02902.14 AIN99315.1 - 5.1e-15 55.6 0.0 2.6e-06 27.2 0.0 2.9 2 1 0 2 2 2 2 Ulp1 protease family, C-terminal catalytic domain Metallophos PF00149.23 AIN99318.1 - 1.2e-17 63.9 0.2 6.6e-16 58.2 0.2 2.9 4 0 0 4 4 4 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 AIN99318.1 - 0.00012 21.9 0.0 0.00054 19.8 0.0 2.0 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase superfamily domain Pkinase PF00069.20 AIN99319.1 - 2.5e-34 118.5 0.0 4.7e-16 58.7 0.0 3.4 3 1 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.12 AIN99319.1 - 4.6e-06 25.8 0.0 0.00017 20.7 0.0 2.9 3 0 0 3 3 3 1 Protein tyrosine kinase BDV_P40 PF06407.6 AIN99319.1 - 0.017 14.0 0.0 0.078 11.8 0.0 2.0 3 0 0 3 3 3 0 Borna disease virus P40 protein Pkinase PF00069.20 AIN99320.1 - 5.5e-07 28.9 0.0 2.9e-05 23.3 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Peptidase_C5 PF00770.13 AIN99320.1 - 2.5 7.5 0.0 6.8 6.1 0.0 1.6 1 0 0 1 1 1 0 Adenovirus endoprotease RRM_5 PF13893.1 AIN99321.1 - 0.032 14.0 0.0 0.21 11.4 0.0 2.1 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Pet191_N PF10203.4 AIN99322.1 - 0.002 18.1 4.3 0.11 12.5 0.3 2.2 1 1 1 2 2 2 2 Cytochrome c oxidase assembly protein PET191 CHCH PF06747.8 AIN99322.1 - 1.3 9.0 8.3 0.077 12.9 1.5 2.2 3 0 0 3 3 3 0 CHCH domain FtsJ PF01728.14 AIN99323.1 - 0.00012 22.0 0.0 0.00082 19.4 0.0 2.0 2 0 0 2 2 2 1 FtsJ-like methyltransferase Arf PF00025.16 AIN99328.1 - 1e-22 80.2 0.3 2.8e-09 36.4 0.0 4.4 3 1 1 4 4 4 3 ADP-ribosylation factor family G-alpha PF00503.15 AIN99328.1 - 9.4e-09 34.4 0.1 0.00069 18.4 0.4 2.3 2 1 0 2 2 2 2 G-protein alpha subunit GTP_EFTU PF00009.22 AIN99328.1 - 6e-05 22.5 0.0 0.21 10.9 0.0 2.3 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain AAA_29 PF13555.1 AIN99328.1 - 0.00015 21.2 0.0 0.0013 18.2 0.0 2.2 2 0 0 2 2 2 1 P-loop containing region of AAA domain SRPRB PF09439.5 AIN99328.1 - 0.00017 20.8 0.0 0.16 11.1 0.0 2.4 2 1 0 2 2 2 2 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.18 AIN99328.1 - 0.00037 20.4 0.0 0.033 14.1 0.0 2.4 2 0 0 2 2 2 1 50S ribosome-binding GTPase ABC_tran PF00005.22 AIN99328.1 - 0.0023 18.2 0.0 0.0084 16.4 0.0 2.0 2 0 0 2 2 2 1 ABC transporter Ras PF00071.17 AIN99328.1 - 0.0035 16.7 0.0 4.3 6.7 0.0 3.7 2 1 0 2 2 2 1 Ras family Dynamin_N PF00350.18 AIN99328.1 - 0.0038 17.0 0.3 0.01 15.6 0.2 1.9 1 1 0 1 1 1 1 Dynamin family Miro PF08477.8 AIN99328.1 - 0.0054 17.2 0.0 0.077 13.4 0.0 2.6 3 0 0 3 3 3 1 Miro-like protein AAA_16 PF13191.1 AIN99328.1 - 0.0056 16.6 7.8 0.21 11.5 5.4 2.4 1 1 0 1 1 1 1 AAA ATPase domain AAA_28 PF13521.1 AIN99328.1 - 0.013 15.4 0.0 0.03 14.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.16 AIN99328.1 - 0.081 12.0 0.0 0.14 11.3 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Septin PF00735.13 AIN99328.1 - 0.084 11.8 0.0 0.17 10.8 0.0 1.5 1 0 0 1 1 1 0 Septin DUF2647 PF10839.3 AIN99328.1 - 0.084 12.9 0.1 0.25 11.4 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2647) AAA_16 PF13191.1 AIN99330.1 - 2.6e-05 24.3 2.3 0.00038 20.4 0.4 2.8 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 AIN99330.1 - 4.5e-05 23.5 0.1 0.52 10.4 0.0 2.6 2 0 0 2 2 2 2 AAA domain Miro PF08477.8 AIN99330.1 - 0.036 14.5 0.0 0.13 12.7 0.0 2.0 1 0 0 1 1 1 0 Miro-like protein Arch_ATPase PF01637.13 AIN99330.1 - 0.044 13.4 0.0 2.3 7.8 0.0 2.8 3 0 0 3 3 3 0 Archaeal ATPase CoaE PF01121.15 AIN99330.1 - 0.054 12.8 0.0 0.18 11.1 0.0 1.9 1 0 0 1 1 1 0 Dephospho-CoA kinase Kinesin PF00225.18 AIN99330.1 - 0.057 12.1 0.0 0.11 11.1 0.0 1.4 1 0 0 1 1 1 0 Kinesin motor domain Ribosomal_L38e PF01781.13 AIN99331.1 - 1.1e-30 105.1 4.2 1.4e-30 104.8 2.9 1.1 1 0 0 1 1 1 1 Ribosomal L38e protein family DUF2359 PF10151.4 AIN99331.1 - 0.075 11.5 0.1 0.075 11.5 0.0 1.0 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2359) Epimerase PF01370.16 AIN99332.1 - 6.3e-55 186.1 0.6 2.3e-53 181.0 0.4 2.1 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 AIN99332.1 - 7.3e-26 90.6 0.2 3.1e-22 78.6 0.0 2.1 2 0 0 2 2 2 2 Male sterility protein RmlD_sub_bind PF04321.12 AIN99332.1 - 1.1e-20 73.7 0.2 1.2e-19 70.3 0.2 2.0 2 0 0 2 2 2 1 RmlD substrate binding domain 3Beta_HSD PF01073.14 AIN99332.1 - 1.5e-19 69.8 0.0 1.3e-13 50.2 0.0 2.2 2 0 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.10 AIN99332.1 - 5.5e-19 68.1 0.0 7.9e-13 47.9 0.0 3.0 2 1 0 2 2 2 2 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.1 AIN99332.1 - 2.1e-07 31.1 0.3 0.00015 21.8 0.0 3.6 1 1 2 3 3 3 1 NADH(P)-binding adh_short PF00106.20 AIN99332.1 - 0.38 10.6 0.1 0.38 10.6 0.0 3.0 3 0 0 3 3 3 0 short chain dehydrogenase Aminotran_5 PF00266.14 AIN99333.1 - 7.8e-14 51.1 0.0 1.1e-13 50.7 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.15 AIN99333.1 - 0.0028 16.0 0.0 0.0041 15.4 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.12 AIN99333.1 - 0.015 14.3 0.0 0.033 13.2 0.0 1.5 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family Sec1 PF00995.18 AIN99335.1 - 1.8e-106 357.0 0.0 2.2e-106 356.7 0.0 1.0 1 0 0 1 1 1 1 Sec1 family CN_hydrolase PF00795.17 AIN99337.1 - 5.1e-27 94.4 0.0 7e-27 93.9 0.0 1.1 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Abhydrolase_6 PF12697.2 AIN99338.1 - 0.0023 17.8 0.1 0.0037 17.1 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.15 AIN99338.1 - 0.1 12.0 0.0 0.19 11.1 0.0 1.5 1 0 0 1 1 1 0 Putative esterase LPP PF04728.8 AIN99339.1 - 1.5 8.7 17.1 2.3 8.0 0.2 6.1 8 0 0 8 8 8 0 Lipoprotein leucine-zipper AMH_N PF04709.7 AIN99340.1 - 0.00023 20.2 0.8 0.00025 20.1 0.6 1.1 1 0 0 1 1 1 1 Anti-Mullerian hormone, N terminal region WD40 PF00400.27 AIN99342.1 - 1.8e-13 49.8 6.1 0.0002 21.0 0.4 4.2 3 1 0 3 3 3 3 WD domain, G-beta repeat DUF4533 PF15047.1 AIN99342.1 - 0.058 12.8 3.4 0.051 12.9 0.5 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF4533) Zip PF02535.17 AIN99342.1 - 0.21 10.5 0.9 0.35 9.8 0.6 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter DUF2749 PF10907.3 AIN99342.1 - 1.1 9.1 4.7 1.5 8.7 0.1 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2749) PQQ_3 PF13570.1 AIN99342.1 - 4.2 7.7 7.1 19 5.7 0.1 4.2 4 0 0 4 4 4 0 PQQ-like domain DUF2151 PF10221.4 AIN99342.1 - 6.2 4.8 12.9 9.1 4.3 8.9 1.2 1 0 0 1 1 1 0 Cell cycle and development regulator BTV_NS2 PF04514.7 AIN99342.1 - 7.3 5.3 14.3 15 4.3 9.9 1.5 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 Ribosomal_L29 PF00831.18 AIN99343.1 - 7.6e-19 67.1 3.2 7.6e-19 67.1 2.2 2.1 2 1 0 2 2 2 1 Ribosomal L29 protein Flavodoxin_3 PF12641.2 AIN99343.1 - 0.11 11.9 0.1 0.12 11.7 0.1 1.2 1 0 0 1 1 1 0 Flavodoxin domain Ribosomal_S9 PF00380.14 AIN99343.1 - 0.2 11.8 5.7 0.36 11.0 3.9 1.6 1 1 0 1 1 1 0 Ribosomal protein S9/S16 MRP-L47 PF06984.8 AIN99343.1 - 0.21 11.5 3.1 0.1 12.5 0.4 1.9 2 1 0 2 2 2 0 Mitochondrial 39-S ribosomal protein L47 (MRP-L47) DUF2989 PF11207.3 AIN99343.1 - 0.75 9.2 3.6 2.5 7.4 0.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2989) Ribosomal_L29 PF00831.18 AIN99344.1 - 7.6e-19 67.1 3.2 7.6e-19 67.1 2.2 2.1 2 1 0 2 2 2 1 Ribosomal L29 protein Flavodoxin_3 PF12641.2 AIN99344.1 - 0.11 11.9 0.1 0.12 11.7 0.1 1.2 1 0 0 1 1 1 0 Flavodoxin domain Ribosomal_S9 PF00380.14 AIN99344.1 - 0.2 11.8 5.7 0.36 11.0 3.9 1.6 1 1 0 1 1 1 0 Ribosomal protein S9/S16 MRP-L47 PF06984.8 AIN99344.1 - 0.21 11.5 3.1 0.1 12.5 0.4 1.9 2 1 0 2 2 2 0 Mitochondrial 39-S ribosomal protein L47 (MRP-L47) DUF2989 PF11207.3 AIN99344.1 - 0.75 9.2 3.6 2.5 7.4 0.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2989) Sec1 PF00995.18 AIN99346.1 - 9.3e-92 308.4 0.0 1.1e-91 308.2 0.0 1.0 1 0 0 1 1 1 1 Sec1 family HECT PF00632.20 AIN99347.1 - 2e-31 109.3 0.0 3.1e-31 108.7 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) SPRY PF00622.23 AIN99347.1 - 2e-14 53.7 0.0 6.1e-14 52.1 0.0 1.9 2 0 0 2 2 2 1 SPRY domain zf-RanBP PF00641.13 AIN99347.1 - 9.9e-07 27.7 15.0 3.6e-05 22.7 1.9 2.8 1 1 1 2 2 2 2 Zn-finger in Ran binding protein and others fn3 PF00041.16 AIN99348.1 - 9.7e-92 301.2 52.2 1.8e-05 24.7 0.3 37.4 40 1 0 40 40 40 21 Fibronectin type III domain Interfer-bind PF09294.5 AIN99348.1 - 3.9e-17 62.2 1.8 3.5 7.6 0.0 15.1 17 0 0 17 17 17 3 Interferon-alpha/beta receptor, fibronectin type III DUF2369 PF10179.4 AIN99348.1 - 0.01 14.9 1.3 15 4.5 0.0 5.3 6 0 0 6 6 6 0 Uncharacterised conserved protein (DUF2369) Y_Y_Y PF07495.8 AIN99348.1 - 0.58 9.9 0.3 3.2e+02 1.1 0.0 4.9 6 0 0 6 6 6 0 Y_Y_Y domain DUF616 PF04765.8 AIN99348.1 - 0.67 9.0 0.0 9.6 5.2 0.0 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF616) Arylsulfotrans PF05935.6 AIN99348.1 - 1.6 7.1 0.0 4.5 5.6 0.0 1.7 1 0 0 1 1 1 0 Arylsulfotransferase (ASST) zf-primase PF09329.6 AIN99349.1 - 4.5e-12 45.3 0.3 1.1e-11 44.1 0.2 1.6 1 0 0 1 1 1 1 Primase zinc finger Mcm10 PF09332.6 AIN99349.1 - 1.8e-08 34.1 4.8 4.4e-08 32.8 3.3 1.6 1 0 0 1 1 1 1 Mcm10 replication factor HypA PF01155.14 AIN99349.1 - 0.24 11.1 1.8 0.55 9.9 1.2 1.7 1 0 0 1 1 1 0 Hydrogenase expression/synthesis hypA family Tim17 PF02466.14 AIN99350.1 - 1.9e-16 60.2 1.1 4.5e-16 59.0 0.5 1.7 2 0 0 2 2 2 1 Tim17/Tim22/Tim23/Pmp24 family DUF2984 PF11203.3 AIN99351.1 - 0.022 14.8 1.7 0.29 11.2 0.4 3.2 2 1 0 2 2 2 0 Protein of unknown function (DUF2984) Snapin_Pallidin PF14712.1 AIN99351.1 - 0.27 11.5 0.2 0.27 11.5 0.1 3.1 3 1 0 3 3 3 0 Snapin/Pallidin BTB PF00651.26 AIN99352.1 - 5.1e-12 45.7 0.1 8.1e-05 22.5 0.0 2.9 2 1 0 2 2 2 2 BTB/POZ domain JAB PF01398.16 AIN99353.1 - 1.6e-17 63.2 0.7 2.1e-10 40.3 0.1 2.4 2 0 0 2 2 2 2 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Prok-JAB PF14464.1 AIN99353.1 - 1.2e-08 34.4 0.8 8.4e-07 28.5 0.6 2.5 1 1 0 1 1 1 1 Prokaryotic homologs of the JAB domain Pkinase PF00069.20 AIN99354.1 - 1.2e-36 126.2 0.0 1.6e-36 125.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AIN99354.1 - 1.7e-25 89.6 0.0 2.5e-25 89.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 AIN99354.1 - 0.00073 18.6 0.2 0.0014 17.6 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 AIN99354.1 - 0.0017 17.3 0.0 0.004 16.1 0.0 1.5 1 0 0 1 1 1 1 Kinase-like DUF2513 PF10711.4 AIN99355.1 - 0.094 12.8 0.0 0.21 11.7 0.0 1.6 1 0 0 1 1 1 0 Hypothetical protein (DUF2513) Atg14 PF10186.4 AIN99355.1 - 3 6.7 6.9 4.1 6.2 4.8 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DUF1542 PF07564.6 AIN99355.1 - 3.4 7.7 6.7 1.2 9.1 0.3 2.4 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1542) RNHCP PF12647.2 AIN99357.1 - 0.16 11.7 3.2 0.53 10.1 1.2 2.2 2 0 0 2 2 2 0 RNHCP domain Mu-like_Com PF10122.4 AIN99357.1 - 0.22 10.6 2.6 2.2 7.3 0.3 2.4 2 0 0 2 2 2 0 Mu-like prophage protein Com ArfGap PF01412.13 AIN99357.1 - 0.26 11.0 4.0 1 9.1 2.0 2.0 1 1 1 2 2 2 0 Putative GTPase activating protein for Arf Stc1 PF12898.2 AIN99357.1 - 3.5 7.7 7.0 3.1 7.9 0.2 2.7 1 1 2 3 3 3 0 Stc1 domain DZR PF12773.2 AIN99357.1 - 4.9 7.0 10.1 4.4e+02 0.7 7.0 2.9 1 1 0 1 1 1 0 Double zinc ribbon zf-B_box PF00643.19 AIN99357.1 - 7.4 6.5 8.5 17 5.4 0.1 3.3 3 0 0 3 3 3 0 B-box zinc finger CDP-OH_P_transf PF01066.16 AIN99358.1 - 9.7e-18 64.3 14.5 4.3e-17 62.2 10.0 2.1 1 1 0 1 1 1 1 CDP-alcohol phosphatidyltransferase IncA PF04156.9 AIN99359.1 - 0.0014 18.2 5.9 0.0014 18.2 4.1 13.7 5 1 5 10 10 10 3 IncA protein CHCH PF06747.8 AIN99360.1 - 6e-06 26.0 10.9 0.0021 17.9 3.8 2.3 2 0 0 2 2 2 2 CHCH domain DUF1903 PF08991.5 AIN99360.1 - 0.0012 18.9 5.4 0.027 14.6 0.6 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF1903) Cmc1 PF08583.5 AIN99360.1 - 1.6 8.5 14.2 6.3 6.6 3.9 3.2 2 2 1 3 3 3 0 Cytochrome c oxidase biogenesis protein Cmc1 like NHR2 PF08788.6 AIN99360.1 - 2.4 7.6 4.9 2.2 7.8 2.5 1.6 1 1 1 2 2 2 0 NHR2 domain like COX6B PF02297.12 AIN99360.1 - 5.2 7.1 10.9 1.5 8.8 4.7 2.2 2 1 0 2 2 2 0 Cytochrome oxidase c subunit VIb Pkinase PF00069.20 AIN99361.1 - 7e-48 163.0 0.0 8.4e-48 162.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AIN99361.1 - 3.1e-28 98.5 0.0 4.3e-28 98.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 AIN99361.1 - 0.0047 16.6 0.1 0.02 14.6 0.0 1.9 2 1 1 3 3 3 1 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.4 AIN99361.1 - 0.0057 16.0 0.0 0.0086 15.4 0.0 1.2 1 0 0 1 1 1 1 PhoP regulatory network protein YrbL Kinase-like PF14531.1 AIN99361.1 - 0.015 14.2 0.0 0.026 13.5 0.0 1.4 1 1 0 1 1 1 0 Kinase-like RIO1 PF01163.17 AIN99361.1 - 0.032 13.5 0.0 0.047 13.0 0.0 1.2 1 0 0 1 1 1 0 RIO1 family Pox_ser-thr_kin PF05445.6 AIN99361.1 - 0.15 10.7 0.0 0.22 10.2 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase DnaJ PF00226.26 AIN99362.1 - 2.8e-06 26.9 0.0 6e-06 25.8 0.0 1.6 1 0 0 1 1 1 1 DnaJ domain Rad50_zn_hook PF04423.9 AIN99362.1 - 0.56 9.7 3.7 0.72 9.3 0.5 2.5 2 0 0 2 2 2 0 Rad50 zinc hook motif zf-C3HC4_3 PF13920.1 AIN99362.1 - 1.9 8.1 18.5 3.4 7.4 3.9 4.0 4 0 0 4 4 4 0 Zinc finger, C3HC4 type (RING finger) SR-25 PF10500.4 AIN99362.1 - 7 6.0 31.6 0.013 15.0 7.1 2.6 2 1 0 2 2 2 0 Nuclear RNA-splicing-associated protein CpXC PF14353.1 AIN99362.1 - 9.4 6.2 8.3 29 4.6 0.2 4.2 3 1 1 4 4 4 0 CpXC protein Metallophos PF00149.23 AIN99363.1 - 2.9e-32 111.6 0.0 4.1e-32 111.2 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase SET PF00856.23 AIN99365.1 - 3.5e-12 46.9 0.0 1.9e-10 41.2 0.0 2.3 1 1 0 1 1 1 1 SET domain Dala_Dala_lig_C PF07478.8 AIN99365.1 - 4.5e-12 45.8 0.0 7.4e-12 45.0 0.0 1.2 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp_4 PF13535.1 AIN99365.1 - 1.3e-10 41.2 0.0 4.2e-10 39.6 0.0 1.8 2 0 0 2 2 2 1 ATP-grasp domain ATP-grasp PF02222.17 AIN99365.1 - 0.00074 18.9 0.0 0.0012 18.2 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain GARS_A PF01071.14 AIN99365.1 - 0.12 11.9 0.0 0.18 11.3 0.0 1.3 1 0 0 1 1 1 0 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain Pkinase PF00069.20 AIN99366.1 - 9.7e-49 165.8 0.0 1.2e-48 165.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AIN99366.1 - 5.7e-34 117.3 0.0 7e-34 117.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase RNase_H2-Ydr279 PF09468.5 AIN99367.1 - 0.12 11.5 0.9 0.13 11.4 0.7 1.0 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) Muted PF14942.1 AIN99367.1 - 0.49 10.2 3.3 0.72 9.7 2.3 1.2 1 0 0 1 1 1 0 Organelle biogenesis, Muted-like protein PqiA PF04403.8 AIN99368.1 - 2e-17 63.2 22.8 1.1e-15 57.6 5.9 3.4 2 1 1 3 3 3 3 Paraquat-inducible protein A FAD_binding_3 PF01494.14 AIN99370.1 - 1.2e-08 34.4 0.0 1.2e-06 27.8 0.0 2.9 2 1 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.1 AIN99370.1 - 6.3e-07 29.3 0.0 1.9e-06 27.7 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 AIN99370.1 - 2.4e-05 23.4 0.0 0.00016 20.6 0.0 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 AIN99370.1 - 0.00014 22.2 0.0 0.00032 21.0 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 AIN99370.1 - 0.00019 20.4 0.1 0.00047 19.1 0.0 1.6 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.9 AIN99370.1 - 0.0027 17.6 0.0 0.0097 15.8 0.0 1.7 1 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 AIN99370.1 - 0.018 13.9 0.3 0.041 12.8 0.0 1.7 2 0 0 2 2 2 0 Lycopene cyclase protein Thi4 PF01946.12 AIN99370.1 - 0.024 13.7 0.0 0.041 12.9 0.0 1.3 1 0 0 1 1 1 0 Thi4 family Pyr_redox_3 PF13738.1 AIN99370.1 - 0.13 12.3 0.0 0.26 11.3 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase zf-CSL PF05207.8 AIN99372.1 - 3.9e-17 61.4 0.3 5.4e-17 61.0 0.2 1.2 1 0 0 1 1 1 1 CSL zinc finger AAA_13 PF13166.1 AIN99373.1 - 0.028 12.8 0.2 0.047 12.1 0.1 1.2 1 0 0 1 1 1 0 AAA domain HECT PF00632.20 AIN99374.1 - 3.3e-05 23.1 0.0 0.003 16.7 0.0 2.8 4 0 0 4 4 4 2 HECT-domain (ubiquitin-transferase) DUF3584 PF12128.3 AIN99375.1 - 0.39 7.9 90.7 0.83 6.8 25.3 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) ABC_membrane PF00664.18 AIN99376.1 - 2.1e-84 283.2 26.7 1.2e-42 146.2 6.9 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 AIN99376.1 - 1.9e-69 232.2 0.0 7.4e-35 120.2 0.0 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.14 AIN99376.1 - 2.3e-12 46.6 0.1 5.2e-06 25.8 0.0 3.6 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 AIN99376.1 - 7.5e-07 29.4 0.0 0.57 10.0 0.1 4.3 3 1 1 4 4 4 1 AAA domain AAA_29 PF13555.1 AIN99376.1 - 1.1e-06 27.9 0.1 0.014 14.9 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain DUF258 PF03193.11 AIN99376.1 - 2e-06 27.0 0.0 0.017 14.3 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_17 PF13207.1 AIN99376.1 - 3.5e-06 27.8 0.0 0.18 12.6 0.0 2.6 2 0 0 2 2 2 2 AAA domain ABC_ATPase PF09818.4 AIN99376.1 - 4.8e-06 25.4 0.5 0.00041 19.0 0.1 2.6 3 0 0 3 3 3 1 Predicted ATPase of the ABC class AAA_22 PF13401.1 AIN99376.1 - 5.2e-05 23.3 2.6 0.3 11.2 0.1 3.9 2 2 0 2 2 2 2 AAA domain AAA PF00004.24 AIN99376.1 - 0.00018 21.7 0.8 1.5 9.0 0.1 3.9 2 2 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.1 AIN99376.1 - 0.00024 20.7 0.2 3.6 7.4 0.0 4.1 4 0 0 4 4 3 1 Part of AAA domain AAA_14 PF13173.1 AIN99376.1 - 0.00044 20.1 0.0 0.31 10.9 0.0 3.0 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.7 AIN99376.1 - 0.0005 19.2 0.0 0.077 12.0 0.0 2.5 2 0 0 2 2 2 1 Zeta toxin AAA_5 PF07728.9 AIN99376.1 - 0.00055 19.6 0.0 0.41 10.3 0.0 3.7 4 0 0 4 4 3 1 AAA domain (dynein-related subfamily) AAA_23 PF13476.1 AIN99376.1 - 0.00097 19.5 0.9 1.4 9.1 0.0 2.5 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.17 AIN99376.1 - 0.0014 18.7 0.3 3.1 8.0 0.0 3.2 3 0 0 3 3 2 2 RNA helicase ATP-synt_ab PF00006.20 AIN99376.1 - 0.0021 17.6 0.0 0.53 9.7 0.0 2.7 2 1 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain AAA_18 PF13238.1 AIN99376.1 - 0.0021 18.3 0.0 2 8.7 0.0 2.8 2 0 0 2 2 2 1 AAA domain SbcCD_C PF13558.1 AIN99376.1 - 0.0024 17.7 5.2 1.4 8.8 0.3 4.0 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_25 PF13481.1 AIN99376.1 - 0.0028 17.1 0.1 6.5 6.0 0.0 3.7 4 0 0 4 4 4 0 AAA domain G-alpha PF00503.15 AIN99376.1 - 0.0036 16.0 0.0 0.25 9.9 0.0 2.2 2 0 0 2 2 2 1 G-protein alpha subunit DUF87 PF01935.12 AIN99376.1 - 0.0037 17.1 0.4 1.4 8.6 0.1 2.5 2 0 0 2 2 2 1 Domain of unknown function DUF87 Viral_helicase1 PF01443.13 AIN99376.1 - 0.0061 16.1 0.2 6 6.3 0.0 3.3 4 0 0 4 4 4 0 Viral (Superfamily 1) RNA helicase AAA_16 PF13191.1 AIN99376.1 - 0.0065 16.4 0.1 2.7 7.9 0.0 2.7 2 0 0 2 2 2 1 AAA ATPase domain Miro PF08477.8 AIN99376.1 - 0.017 15.6 0.0 8 6.9 0.0 2.8 2 0 0 2 2 2 0 Miro-like protein Rad17 PF03215.10 AIN99376.1 - 0.028 13.1 0.0 1.1 7.8 0.0 2.4 2 0 0 2 2 2 0 Rad17 cell cycle checkpoint protein AAA_28 PF13521.1 AIN99376.1 - 0.031 14.2 0.6 1.8 8.4 0.0 2.5 2 0 0 2 2 2 0 AAA domain DUF815 PF05673.8 AIN99376.1 - 0.061 12.2 0.0 8.7 5.1 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF815) MMR_HSR1 PF01926.18 AIN99376.1 - 0.074 13.0 0.0 11 5.9 0.0 3.1 2 0 0 2 2 2 0 50S ribosome-binding GTPase Abi PF02517.11 AIN99378.1 - 1.1e-18 67.1 0.9 2.5e-18 66.0 0.1 2.0 2 0 0 2 2 2 1 CAAX protease self-immunity Glucosamine_iso PF01182.15 AIN99379.1 - 5.5e-45 153.5 0.1 6.4e-45 153.3 0.0 1.0 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase AA_kinase PF00696.23 AIN99380.1 - 4.5e-40 137.7 0.2 5.1e-40 137.5 0.1 1.0 1 0 0 1 1 1 1 Amino acid kinase family TPR_20 PF14561.1 AIN99382.1 - 0.00018 21.5 1.6 0.015 15.4 0.0 3.8 3 2 1 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.12 AIN99382.1 - 0.001 18.8 3.7 0.68 9.9 0.1 3.8 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.1 AIN99382.1 - 0.0021 18.5 5.0 0.42 11.3 0.0 4.2 4 1 0 4 4 4 1 Tetratricopeptide repeat TPR_12 PF13424.1 AIN99382.1 - 0.0032 17.3 0.2 0.17 11.8 0.0 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.1 AIN99382.1 - 0.012 15.8 5.8 0.44 10.9 0.0 4.3 4 1 0 4 4 4 0 Tetratricopeptide repeat TPR_16 PF13432.1 AIN99382.1 - 0.018 15.7 5.7 11 6.8 0.1 3.8 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_11 PF13414.1 AIN99382.1 - 0.019 14.5 2.8 3.2 7.4 0.7 3.5 2 1 1 3 3 3 0 TPR repeat TPR_15 PF13429.1 AIN99382.1 - 0.037 13.0 0.5 0.073 12.1 0.4 1.4 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_6 PF13174.1 AIN99382.1 - 0.041 14.3 3.4 1.6 9.3 0.1 4.1 3 1 1 4 4 4 0 Tetratricopeptide repeat Thioredoxin PF00085.15 AIN99382.1 - 0.074 12.7 0.0 0.15 11.7 0.0 1.5 1 0 0 1 1 1 0 Thioredoxin DUF4398 PF14346.1 AIN99382.1 - 0.92 9.5 5.3 20 5.3 1.3 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4398) TGT PF01702.13 AIN99383.1 - 1.9e-32 112.4 0.0 8.4e-32 110.3 0.0 1.8 1 1 0 1 1 1 1 Queuine tRNA-ribosyltransferase Peptidase_M48 PF01435.13 AIN99384.1 - 5.3e-42 143.8 0.0 8e-42 143.3 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M48 Peptidase_M56 PF05569.6 AIN99384.1 - 0.021 13.8 0.0 0.062 12.2 0.0 1.7 2 0 0 2 2 2 0 BlaR1 peptidase M56 DEAD PF00270.24 AIN99385.1 - 3.4e-37 127.5 0.1 5.9e-37 126.7 0.1 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 AIN99385.1 - 9.6e-21 73.4 0.0 1.5e-19 69.5 0.0 2.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DUF4217 PF13959.1 AIN99385.1 - 3.8e-11 42.3 0.5 8.7e-11 41.2 0.3 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.10 AIN99385.1 - 0.00025 20.9 0.0 0.0009 19.1 0.0 2.0 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Viral_helicase1 PF01443.13 AIN99385.1 - 0.035 13.6 0.0 0.12 11.8 0.0 1.8 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase AAA_22 PF13401.1 AIN99385.1 - 0.76 9.9 6.0 0.99 9.5 0.6 3.4 3 1 0 3 3 3 0 AAA domain CcmD PF04995.9 AIN99386.1 - 0.036 13.8 0.3 0.05 13.3 0.2 1.2 1 0 0 1 1 1 0 Heme exporter protein D (CcmD) Lysis_S PF04971.7 AIN99386.1 - 0.049 13.3 0.1 0.065 12.9 0.0 1.2 1 0 0 1 1 1 0 Lysis protein S DUF4381 PF14316.1 AIN99386.1 - 0.11 12.5 0.2 0.12 12.4 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) DUF2162 PF09930.4 AIN99386.1 - 0.13 11.3 0.0 0.14 11.2 0.0 1.0 1 0 0 1 1 1 0 Predicted transporter (DUF2162) THEG PF14912.1 AIN99388.1 - 0.55 10.8 4.0 6.5 7.3 0.1 3.1 3 0 0 3 3 3 0 Testicular haploid expressed repeat p450 PF00067.17 AIN99389.1 - 2e-56 191.4 0.0 2.7e-56 191.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Pkinase PF00069.20 AIN99390.1 - 9.4e-66 221.6 0.0 1.2e-65 221.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AIN99390.1 - 1.1e-28 100.0 0.0 1.7e-28 99.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase GATA PF00320.22 AIN99390.1 - 0.072 12.4 1.6 0.17 11.2 1.1 1.6 1 0 0 1 1 1 0 GATA zinc finger NUDE_C PF04880.8 AIN99390.1 - 4.5 7.6 12.1 0.08 13.3 3.0 2.0 2 0 0 2 2 2 0 NUDE protein, C-terminal conserved region PsbX PF06596.6 AIN99391.1 - 0.36 10.5 1.4 0.54 9.9 1.0 1.2 1 0 0 1 1 1 0 Photosystem II reaction centre X protein (PsbX) RINGv PF12906.2 AIN99392.1 - 2.4e-09 37.1 11.2 5e-09 36.0 7.7 1.6 1 0 0 1 1 1 1 RING-variant domain PHD PF00628.24 AIN99392.1 - 1.7 8.4 10.3 3.1 7.5 7.1 1.5 1 0 0 1 1 1 0 PHD-finger WW PF00397.21 AIN99393.1 - 4.8e-11 42.3 2.8 4.8e-11 42.3 1.9 1.7 2 0 0 2 2 2 1 WW domain zf-CCCH PF00642.19 AIN99393.1 - 7.7e-07 28.6 0.3 1.1e-06 28.1 0.2 1.3 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) GAD-like PF08887.6 AIN99393.1 - 0.16 12.0 0.4 0.88 9.6 0.0 2.0 2 0 0 2 2 2 0 GAD-like domain zf-CCCH PF00642.19 AIN99395.1 - 0.00086 18.9 0.3 0.0013 18.3 0.2 1.2 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) SET PF00856.23 AIN99396.1 - 9e-12 45.5 0.5 2.6e-11 44.1 0.3 1.9 1 1 0 1 1 1 1 SET domain OSTMP1 PF09777.4 AIN99396.1 - 0.13 11.4 0.5 0.18 10.9 0.4 1.2 1 0 0 1 1 1 0 Osteopetrosis-associated transmembrane protein 1 precursor SIT PF15330.1 AIN99398.1 - 0.12 12.4 0.0 0.19 11.8 0.0 1.2 1 0 0 1 1 1 0 SHP2-interacting transmembrane adaptor protein, SIT Proteasome PF00227.21 AIN99399.1 - 7.5e-43 146.0 0.1 9.4e-43 145.7 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 AIN99399.1 - 9.9e-10 37.5 0.1 9.9e-10 37.5 0.1 1.7 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature VIT1 PF01988.14 AIN99401.1 - 4.6e-59 199.4 5.2 5.4e-59 199.2 3.6 1.1 1 0 0 1 1 1 1 VIT family THF_DHG_CYH_C PF02882.14 AIN99402.1 - 0.096 11.7 0.0 0.16 10.9 0.0 1.4 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain NAD_binding_2 PF03446.10 AIN99404.1 - 0.022 14.6 0.6 0.027 14.2 0.4 1.2 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase DUF4626 PF15422.1 AIN99404.1 - 0.075 12.9 0.1 0.13 12.1 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4626) Spore_coat_CotO PF14153.1 AIN99404.1 - 0.22 10.9 2.3 0.23 10.8 1.6 1.1 1 0 0 1 1 1 0 Spore coat protein CotO DUF1501 PF07394.7 AIN99404.1 - 0.35 9.6 2.3 0.38 9.5 1.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1501) MAP7 PF05672.6 AIN99404.1 - 8.9 5.6 18.8 5.1 6.4 5.9 2.0 1 1 1 2 2 2 0 MAP7 (E-MAP-115) family MAP7 PF05672.6 AIN99405.1 - 1.5 8.1 41.2 17 4.7 28.5 2.7 1 1 0 1 1 1 0 MAP7 (E-MAP-115) family F-protein PF00469.15 AIN99405.1 - 7.3 5.8 7.0 8.8 5.6 4.8 1.2 1 0 0 1 1 1 0 Negative factor, (F-Protein) or Nef XPG_I PF00867.13 AIN99406.1 - 4.1e-30 103.6 0.1 7.9e-30 102.7 0.0 1.5 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.12 AIN99406.1 - 4.7e-27 94.2 0.0 8.9e-27 93.3 0.0 1.5 1 0 0 1 1 1 1 XPG N-terminal domain 5_3_exonuc PF01367.15 AIN99406.1 - 1.3e-05 25.3 0.0 0.00011 22.3 0.0 2.2 2 0 0 2 2 2 1 5'-3' exonuclease, C-terminal SAM fold Sigma70_r1_1 PF03979.9 AIN99406.1 - 0.025 14.4 0.2 0.1 12.5 0.0 2.0 2 0 0 2 2 2 0 Sigma-70 factor, region 1.1 XPG_I_2 PF12813.2 AIN99406.1 - 0.044 13.2 0.0 0.062 12.7 0.0 1.2 1 0 0 1 1 1 0 XPG domain containing PP-binding PF00550.20 AIN99409.1 - 1.9e-10 40.8 0.1 2.7e-10 40.3 0.1 1.2 1 0 0 1 1 1 1 Phosphopantetheine attachment site PP-binding_2 PF14573.1 AIN99409.1 - 0.12 12.4 0.5 0.18 11.8 0.4 1.3 1 1 0 1 1 1 0 Acyl-carrier MM_CoA_mutase PF01642.17 AIN99410.1 - 1.2e-224 746.2 1.4 1.4e-224 746.0 1.0 1.0 1 0 0 1 1 1 1 Methylmalonyl-CoA mutase B12-binding PF02310.14 AIN99410.1 - 1.2e-10 41.2 0.1 2.9e-10 40.0 0.1 1.6 1 0 0 1 1 1 1 B12 binding domain HisG_C PF08029.6 AIN99410.1 - 0.015 15.1 0.0 0.049 13.5 0.0 1.8 1 0 0 1 1 1 0 HisG, C-terminal domain TIP120 PF08623.5 AIN99411.1 - 2.9e-08 33.4 0.2 2.9e-07 30.2 0.0 2.4 2 0 0 2 2 2 1 TATA-binding protein interacting (TIP20) Adaptin_N PF01602.15 AIN99411.1 - 0.0098 14.2 12.3 0.011 14.0 0.2 3.5 4 0 0 4 4 4 3 Adaptin N terminal region TniQ PF06527.6 AIN99412.1 - 0.037 14.2 2.0 0.69 10.1 0.1 3.2 2 1 1 3 3 3 0 TniQ DUF3492 PF11997.3 AIN99413.1 - 5.6 6.4 12.0 25 4.3 2.9 3.1 2 1 1 3 3 3 0 Domain of unknown function (DUF3492) RRM_1 PF00076.17 AIN99415.1 - 1e-16 60.3 0.0 2.8e-08 33.2 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 AIN99415.1 - 2e-14 53.3 0.0 1.9e-09 37.3 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 AIN99415.1 - 3.1e-08 33.3 0.0 4e-06 26.5 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) AAA PF00004.24 AIN99416.1 - 3.3e-36 124.4 0.0 6.1e-35 120.2 0.0 2.5 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 AIN99416.1 - 1e-08 35.3 0.2 0.012 15.5 0.0 3.6 4 0 0 4 4 4 2 AAA ATPase domain AAA_17 PF13207.1 AIN99416.1 - 0.00029 21.6 0.0 0.00085 20.1 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.1 AIN99416.1 - 0.0018 18.2 0.0 0.028 14.3 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.9 AIN99416.1 - 0.0019 17.9 0.0 0.0083 15.8 0.0 2.2 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) Rad17 PF03215.10 AIN99416.1 - 0.0024 16.6 0.0 0.024 13.3 0.0 2.0 2 0 0 2 2 2 1 Rad17 cell cycle checkpoint protein AAA_22 PF13401.1 AIN99416.1 - 0.0029 17.7 0.0 1.1 9.4 0.0 3.5 2 2 1 3 3 3 1 AAA domain RNA_helicase PF00910.17 AIN99416.1 - 0.0095 16.0 0.0 0.23 11.6 0.0 2.4 2 0 0 2 2 2 1 RNA helicase Arch_ATPase PF01637.13 AIN99416.1 - 0.027 14.1 0.0 1 9.0 0.0 2.5 2 1 1 3 3 3 0 Archaeal ATPase DUF815 PF05673.8 AIN99416.1 - 0.041 12.8 0.0 1.7 7.4 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF815) RuvB_N PF05496.7 AIN99416.1 - 0.13 11.2 0.0 0.25 10.3 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus Herpes_UL49_5 PF05702.6 AIN99417.1 - 0.044 13.6 0.1 0.084 12.7 0.1 1.4 1 0 0 1 1 1 0 Herpesvirus UL49.5 envelope/tegument protein Nup96 PF12110.3 AIN99418.1 - 9.2e-53 179.2 0.0 1.5e-52 178.5 0.0 1.3 1 0 0 1 1 1 1 Nuclear protein 96 Nucleoporin2 PF04096.9 AIN99418.1 - 2.8e-21 75.7 0.0 6.8e-21 74.5 0.0 1.7 1 1 0 1 1 1 1 Nucleoporin autopeptidase MutS_III PF05192.13 AIN99418.1 - 0.029 14.1 0.1 0.17 11.6 0.0 2.1 2 0 0 2 2 2 0 MutS domain III APG9 PF04109.11 AIN99419.1 - 4.1e-43 147.7 0.2 1.9e-42 145.5 0.1 1.8 1 1 0 1 1 1 1 Autophagy protein Apg9 RSS_P20 PF11757.3 AIN99420.1 - 0.018 15.1 0.1 0.029 14.4 0.0 1.5 1 1 0 1 1 1 0 Suppressor of RNA silencing P21-like YojJ PF10372.4 AIN99420.1 - 0.083 12.7 0.4 0.17 11.7 0.1 1.7 1 1 0 1 1 1 0 Bacterial membrane-spanning protein N-terminus DnaJ PF00226.26 AIN99421.1 - 4e-25 87.3 0.7 7.2e-25 86.5 0.5 1.4 1 0 0 1 1 1 1 DnaJ domain Tic20 PF09685.5 AIN99421.1 - 0.045 13.7 2.7 0.075 13.0 1.8 1.3 1 0 0 1 1 1 0 Tic20-like protein CytB6-F_Fe-S PF08802.5 AIN99421.1 - 3 7.9 5.8 7.4 6.6 1.8 2.3 2 0 0 2 2 2 0 Cytochrome B6-F complex Fe-S subunit PfkB PF00294.19 AIN99422.1 - 2.2e-62 210.9 0.1 2.5e-62 210.7 0.1 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.7 AIN99422.1 - 6.3e-09 35.3 0.0 9.4e-09 34.8 0.0 1.2 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase Mur_ligase PF01225.20 AIN99422.1 - 0.0022 17.9 0.1 0.066 13.2 0.0 2.6 2 1 0 2 2 2 1 Mur ligase family, catalytic domain Brix PF04427.13 AIN99425.1 - 1.1e-43 149.1 0.2 1.9e-43 148.3 0.1 1.4 1 0 0 1 1 1 1 Brix domain Vasohibin PF14822.1 AIN99426.1 - 1.6e-48 164.9 0.0 3.3e-48 163.9 0.0 1.4 1 0 0 1 1 1 1 Vasohibin ABC_membrane_2 PF06472.10 AIN99427.1 - 1.6e-26 93.0 1.7 1.6e-26 93.0 1.2 1.6 2 0 0 2 2 2 1 ABC transporter transmembrane region 2 ABC_tran PF00005.22 AIN99427.1 - 5.1e-14 52.7 0.0 1.1e-13 51.6 0.0 1.6 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.14 AIN99427.1 - 1.7e-07 30.7 0.0 6.5e-06 25.5 0.0 2.2 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain NACHT PF05729.7 AIN99427.1 - 2e-05 24.3 0.0 4e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 AIN99427.1 - 0.00087 19.3 0.0 0.0018 18.2 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain ABC_membrane PF00664.18 AIN99427.1 - 0.00088 18.7 1.3 0.0014 18.0 0.7 1.5 1 1 0 1 1 1 1 ABC transporter transmembrane region AAA_21 PF13304.1 AIN99427.1 - 0.0018 18.2 0.0 0.013 15.4 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 AIN99427.1 - 0.0046 17.0 0.3 0.065 13.3 0.2 2.4 1 1 0 1 1 1 1 AAA domain AAA_23 PF13476.1 AIN99427.1 - 0.016 15.5 0.0 0.027 14.7 0.0 1.2 1 0 0 1 1 1 0 AAA domain SbcCD_C PF13558.1 AIN99427.1 - 0.021 14.7 0.0 0.045 13.6 0.0 1.6 1 0 0 1 1 1 0 Putative exonuclease SbcCD, C subunit GRDA PF04723.9 AIN99427.1 - 0.033 13.9 0.0 0.065 12.9 0.0 1.4 1 0 0 1 1 1 0 Glycine reductase complex selenoprotein A Arch_ATPase PF01637.13 AIN99427.1 - 0.05 13.2 0.0 0.18 11.4 0.0 1.9 1 1 0 1 1 1 0 Archaeal ATPase Miro PF08477.8 AIN99427.1 - 0.069 13.6 0.0 0.19 12.2 0.0 1.7 1 0 0 1 1 1 0 Miro-like protein DUF3584 PF12128.3 AIN99427.1 - 0.11 9.8 0.0 0.15 9.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Sigma54_activ_2 PF14532.1 AIN99427.1 - 0.12 12.4 0.0 5 7.1 0.0 2.5 2 0 0 2 2 2 0 Sigma-54 interaction domain HTH_43 PF09904.4 AIN99427.1 - 0.13 12.0 0.1 0.3 10.9 0.1 1.6 1 0 0 1 1 1 0 Winged helix-turn helix AAA_15 PF13175.1 AIN99427.1 - 0.31 10.0 0.0 0.5 9.3 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain Methyltransf_2 PF00891.13 AIN99428.1 - 0.1 11.7 0.1 1.3 8.1 0.0 2.0 1 1 1 2 2 2 0 O-methyltransferase SH3_3 PF08239.6 AIN99428.1 - 0.18 12.0 2.0 6.7 6.9 0.0 3.2 4 0 0 4 4 4 0 Bacterial SH3 domain Peptidase_C2 PF00648.16 AIN99429.1 - 1.5e-52 178.4 0.0 1e-26 93.6 0.0 2.3 2 0 0 2 2 2 2 Calpain family cysteine protease Calpain_III PF01067.17 AIN99429.1 - 7.5e-21 74.3 0.1 1.7e-11 43.9 0.0 3.2 3 0 0 3 3 3 2 Calpain large subunit, domain III Peptidase_C2 PF00648.16 AIN99430.1 - 8e-14 51.3 0.0 1.3e-13 50.6 0.0 1.3 1 0 0 1 1 1 1 Calpain family cysteine protease Peptidase_C2 PF00648.16 AIN99431.1 - 3.4e-75 252.8 0.0 2.8e-29 102.0 0.0 3.3 3 0 0 3 3 3 3 Calpain family cysteine protease Calpain_III PF01067.17 AIN99431.1 - 4.3e-28 97.8 0.0 7.4e-10 38.6 0.0 3.8 3 0 0 3 3 3 3 Calpain large subunit, domain III phage_tail_N PF08400.5 AIN99431.1 - 0.75 9.5 0.2 91 2.7 0.0 3.8 4 0 0 4 4 4 0 Prophage tail fibre N-terminal Peptidase_C2 PF00648.16 AIN99432.1 - 7.1e-71 238.6 0.0 3.5e-26 91.8 0.0 3.3 3 0 0 3 3 3 3 Calpain family cysteine protease Calpain_III PF01067.17 AIN99432.1 - 3.4e-21 75.4 0.0 7.3e-08 32.1 0.0 4.2 4 0 0 4 4 4 3 Calpain large subunit, domain III Fib_alpha PF08702.5 AIN99432.1 - 2.9 8.0 14.2 1.3 9.0 0.3 5.4 5 0 0 5 5 5 0 Fibrinogen alpha/beta chain family FHIPEP PF00771.15 AIN99432.1 - 3.2 5.9 0.1 6.3 5.0 0.1 1.4 1 0 0 1 1 1 0 FHIPEP family Radial_spoke_3 PF06098.6 AIN99433.1 - 6.5e-117 389.6 28.6 7.6e-117 389.4 19.8 1.0 1 0 0 1 1 1 1 Radial spoke protein 3 eIF3_p135 PF12807.2 AIN99433.1 - 0.011 15.6 2.5 0.024 14.5 1.7 1.5 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit 135 Vfa1 PF08432.5 AIN99433.1 - 4.3 7.3 15.4 3.7 7.5 5.0 2.3 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 Amastin PF07344.6 AIN99435.1 - 7.6e-09 35.3 6.3 7.6e-09 35.3 4.4 1.7 2 0 0 2 2 2 1 Amastin surface glycoprotein DUF948 PF06103.6 AIN99435.1 - 0.026 14.3 0.3 0.026 14.3 0.2 2.0 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Rep_fac_C PF08542.6 AIN99436.1 - 9.8e-17 60.7 0.2 6.1e-16 58.1 0.0 2.3 3 0 0 3 3 3 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.1 AIN99436.1 - 7.4e-13 48.4 0.0 2.4e-12 46.7 0.0 1.8 1 1 0 1 1 1 1 DNA polymerase III, delta subunit AAA PF00004.24 AIN99436.1 - 2.2e-11 44.0 0.2 1e-10 41.9 0.0 2.2 3 0 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.10 AIN99436.1 - 1.2e-09 37.3 0.0 9.4e-07 27.8 0.0 2.2 2 0 0 2 2 2 2 Rad17 cell cycle checkpoint protein AAA_22 PF13401.1 AIN99436.1 - 1.3e-07 31.8 0.1 3.9e-07 30.2 0.0 1.8 2 0 0 2 2 1 1 AAA domain Mg_chelatase PF01078.16 AIN99436.1 - 1.7e-05 24.1 0.1 0.00073 18.7 0.0 2.2 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_16 PF13191.1 AIN99436.1 - 3.8e-05 23.7 0.6 0.001 19.1 0.4 2.5 1 1 0 1 1 1 1 AAA ATPase domain RuvB_N PF05496.7 AIN99436.1 - 5.9e-05 22.2 0.0 0.00015 20.8 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 AIN99436.1 - 0.00011 21.8 0.0 0.00033 20.3 0.0 1.9 1 0 0 1 1 1 1 Part of AAA domain DNA_pol3_delta PF06144.8 AIN99436.1 - 0.00031 20.3 0.2 0.00084 18.8 0.0 1.7 2 0 0 2 2 2 1 DNA polymerase III, delta subunit AAA_25 PF13481.1 AIN99436.1 - 0.00038 19.9 0.1 0.0011 18.4 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_10 PF12846.2 AIN99436.1 - 0.0012 18.3 0.0 0.0024 17.3 0.0 1.8 1 1 0 1 1 1 1 AAA-like domain AAA_14 PF13173.1 AIN99436.1 - 0.0013 18.6 0.0 0.0041 17.0 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.1 AIN99436.1 - 0.0018 17.8 0.1 0.0055 16.3 0.0 1.8 2 0 0 2 2 2 1 AAA domain FtsK_SpoIIIE PF01580.13 AIN99436.1 - 0.0021 17.5 0.0 0.004 16.6 0.0 1.4 1 0 0 1 1 1 1 FtsK/SpoIIIE family RNA_helicase PF00910.17 AIN99436.1 - 0.0084 16.2 0.0 0.035 14.2 0.0 2.1 3 0 0 3 3 2 1 RNA helicase AAA_5 PF07728.9 AIN99436.1 - 0.011 15.3 0.0 0.24 11.0 0.0 2.4 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) DUF2075 PF09848.4 AIN99436.1 - 0.011 14.6 0.0 0.018 14.0 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_33 PF13671.1 AIN99436.1 - 0.027 14.3 0.1 0.086 12.7 0.0 1.9 2 0 0 2 2 1 0 AAA domain IstB_IS21 PF01695.12 AIN99436.1 - 0.039 13.3 0.0 0.078 12.3 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_11 PF13086.1 AIN99436.1 - 0.04 13.4 0.0 0.059 12.9 0.0 1.4 1 1 0 1 1 1 0 AAA domain AAA_24 PF13479.1 AIN99436.1 - 0.056 13.0 0.1 0.13 11.8 0.1 1.6 1 0 0 1 1 1 0 AAA domain TIP49 PF06068.8 AIN99436.1 - 0.061 12.0 0.2 0.81 8.3 0.0 2.2 2 0 0 2 2 2 0 TIP49 C-terminus AAA_18 PF13238.1 AIN99436.1 - 0.07 13.4 0.0 0.14 12.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_3 PF07726.6 AIN99436.1 - 0.071 12.7 0.0 18 4.9 0.0 2.7 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Pkinase PF00069.20 AIN99437.1 - 1.8e-62 210.8 0.0 2.1e-62 210.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AIN99437.1 - 6.5e-27 94.2 0.0 8.6e-27 93.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 AIN99437.1 - 0.034 13.8 0.1 0.075 12.7 0.0 1.6 1 1 1 2 2 2 0 Phosphotransferase enzyme family zf-RING_2 PF13639.1 AIN99438.1 - 7.1e-10 38.5 8.4 7.1e-10 38.5 5.8 2.5 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.20 AIN99438.1 - 2.2e-07 30.3 8.2 2.2e-07 30.3 5.7 2.3 3 0 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 AIN99438.1 - 2.6e-07 30.2 8.2 2.6e-07 30.2 5.7 2.8 2 1 1 3 3 2 1 zinc-RING finger domain zf-rbx1 PF12678.2 AIN99438.1 - 7.9e-07 29.0 2.1 7.9e-07 29.0 1.5 2.6 2 0 0 2 2 2 1 RING-H2 zinc finger PHD PF00628.24 AIN99438.1 - 2.7e-06 26.9 5.9 2.7e-06 26.9 4.1 2.5 2 0 0 2 2 2 1 PHD-finger zf-C3HC4_3 PF13920.1 AIN99438.1 - 3.9e-06 26.4 6.1 3.9e-06 26.4 4.2 2.6 2 1 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 AIN99438.1 - 0.00021 21.2 9.2 0.00021 21.2 6.4 2.7 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 AIN99438.1 - 0.0018 17.9 4.8 0.0018 17.9 3.4 1.9 2 0 0 2 2 2 1 RING-type zinc-finger zf-UDP PF14569.1 AIN99438.1 - 0.024 14.3 2.0 0.083 12.6 1.4 1.9 1 0 0 1 1 1 0 Zinc-binding RING-finger EIIA-man PF03610.11 AIN99438.1 - 0.12 12.4 0.0 25 4.9 0.0 2.4 1 1 1 2 2 2 0 PTS system fructose IIA component zf-RING_6 PF14835.1 AIN99438.1 - 0.17 11.6 3.3 0.75 9.6 2.3 2.1 1 1 0 1 1 1 0 zf-RING of BARD1-type protein Prok-RING_4 PF14447.1 AIN99438.1 - 0.43 10.1 7.7 1.1 8.8 5.3 1.7 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-Apc11 PF12861.2 AIN99438.1 - 0.65 9.8 12.1 0.038 13.8 3.7 2.3 2 1 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_4 PF15227.1 AIN99438.1 - 1.3 8.9 14.2 0.035 13.9 3.8 2.5 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING Herpes_BLLF1 PF05109.8 AIN99438.1 - 1.3 6.8 20.9 2.3 6.0 14.5 1.3 1 0 0 1 1 1 0 Herpes virus major outer envelope glycoprotein (BLLF1) Rtf2 PF04641.7 AIN99438.1 - 3.2 6.9 10.7 0.028 13.6 0.7 2.3 2 1 0 3 3 3 0 Rtf2 RING-finger FANCL_C PF11793.3 AIN99438.1 - 3.2 7.8 18.1 2.5 8.1 2.3 3.1 2 1 0 2 2 2 0 FANCL C-terminal domain zf-RING_4 PF14570.1 AIN99438.1 - 6.9 6.3 21.5 0.037 13.6 5.6 3.0 2 1 0 2 2 2 0 RING/Ubox like zinc-binding domain WD40 PF00400.27 AIN99439.1 - 1.1e-10 41.0 1.7 0.011 15.5 0.0 5.0 4 0 0 4 4 4 4 WD domain, G-beta repeat LisH PF08513.6 AIN99439.1 - 4.3e-05 23.1 0.2 7.7e-05 22.3 0.1 1.5 1 0 0 1 1 1 1 LisH DUF4471 PF14740.1 AIN99440.1 - 3.1e-87 292.4 0.0 4.1e-87 292.0 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4471) DUF4470 PF14737.1 AIN99440.1 - 3.5e-21 74.8 0.0 9.6e-21 73.4 0.0 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4470) MRP-S28 PF10213.4 AIN99444.1 - 0.00029 20.9 0.0 0.0008 19.4 0.0 1.7 1 0 0 1 1 1 1 Mitochondrial ribosomal subunit protein TMEM154 PF15102.1 AIN99447.1 - 4.5e-05 23.1 4.1 0.00011 21.9 2.9 1.6 1 0 0 1 1 1 1 TMEM154 protein family AJAP1_PANP_C PF15298.1 AIN99447.1 - 0.0029 17.5 13.0 0.0096 15.8 9.0 1.8 1 0 0 1 1 1 1 AJAP1/PANP C-terminus gpUL132 PF11359.3 AIN99447.1 - 0.017 14.4 10.8 0.032 13.5 7.5 1.5 1 0 0 1 1 1 0 Glycoprotein UL132 ABC2_membrane_3 PF12698.2 AIN99447.1 - 0.032 13.2 0.6 0.046 12.7 0.4 1.2 1 0 0 1 1 1 0 ABC-2 family transporter protein Herpes_gE PF02480.11 AIN99447.1 - 0.04 12.1 5.3 0.0089 14.3 1.3 1.6 2 0 0 2 2 2 0 Alphaherpesvirus glycoprotein E Hum_adeno_E3A PF05393.6 AIN99447.1 - 1.6 8.4 6.8 11 5.7 0.1 2.7 2 1 0 2 2 2 0 Human adenovirus early E3A glycoprotein Aa_trans PF01490.13 AIN99448.1 - 7e-52 176.2 33.3 8.7e-52 175.9 23.1 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Aa_trans PF01490.13 AIN99449.1 - 8.3e-42 143.0 36.7 1e-41 142.8 25.5 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.8 AIN99449.1 - 3.6e-09 35.9 21.3 3.6e-09 35.9 14.8 1.7 2 0 0 2 2 2 1 Tryptophan/tyrosine permease family AA_permease_2 PF13520.1 AIN99449.1 - 6.7e-08 31.4 26.6 6.7e-08 31.4 18.4 1.9 2 0 0 2 2 2 1 Amino acid permease HXXEE PF13787.1 AIN99449.1 - 0.0052 17.1 1.1 0.0052 17.1 0.8 3.4 3 1 1 4 4 4 1 Protein of unknown function with HXXEE motif DUF1860 PF08949.5 AIN99450.1 - 0.0024 17.5 0.2 0.17 11.4 0.0 2.7 2 0 0 2 2 2 2 Domain of unknown function (DUF1860) LRR_4 PF12799.2 AIN99450.1 - 0.0026 17.3 0.0 0.014 15.0 0.0 2.2 1 1 1 2 2 2 2 Leucine Rich repeats (2 copies) DHHA1 PF02272.14 AIN99451.1 - 1.5 8.6 5.4 2.8 7.7 0.4 2.6 2 0 0 2 2 2 0 DHHA1 domain UBA PF00627.26 AIN99453.1 - 2.1e-09 36.9 0.1 6.4e-09 35.3 0.1 1.9 1 0 0 1 1 1 1 UBA/TS-N domain NAD_binding_1 PF00175.16 AIN99454.1 - 4.9e-17 62.4 0.0 7.1e-17 61.9 0.0 1.2 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.7 AIN99454.1 - 1.9e-05 24.6 0.0 0.00025 20.9 0.0 2.1 2 0 0 2 2 2 1 Ferric reductase NAD binding domain Oxidored_q6 PF01058.17 AIN99455.1 - 2.5e-19 69.2 0.0 3.2e-19 68.8 0.0 1.2 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase, 20 Kd subunit Dabb PF07876.7 AIN99456.1 - 3.3e-11 43.4 0.0 4.3e-11 43.1 0.0 1.2 1 0 0 1 1 1 1 Stress responsive A/B Barrel Domain DsbC_N PF10411.4 AIN99456.1 - 0.026 13.7 0.0 0.041 13.1 0.0 1.3 1 0 0 1 1 1 0 Disulfide bond isomerase protein N-terminus Dabb PF07876.7 AIN99457.1 - 3.4e-06 27.4 0.0 5e-06 26.8 0.0 1.3 1 0 0 1 1 1 1 Stress responsive A/B Barrel Domain Ras PF00071.17 AIN99458.1 - 2.7e-64 215.4 0.6 3.1e-64 215.2 0.4 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 AIN99458.1 - 1.1e-21 77.4 0.1 1.7e-21 76.9 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 AIN99458.1 - 5.8e-16 58.2 0.1 7e-16 57.9 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 AIN99458.1 - 9.6e-08 31.4 0.1 1.2e-07 31.1 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 AIN99458.1 - 1.2e-05 24.7 0.3 2.4e-05 23.8 0.2 1.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.5 AIN99458.1 - 3e-05 23.3 0.1 3.7e-05 23.0 0.1 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.18 AIN99458.1 - 0.00022 21.1 0.1 0.00038 20.3 0.1 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 AIN99458.1 - 0.00042 19.6 0.1 0.0023 17.2 0.0 1.9 1 1 0 1 1 1 1 Ferrous iron transport protein B AAA_22 PF13401.1 AIN99458.1 - 0.0021 18.1 0.0 0.0046 17.0 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA PF00004.24 AIN99458.1 - 0.0035 17.5 0.0 0.31 11.2 0.0 2.3 1 1 1 2 2 2 1 ATPase family associated with various cellular activities (AAA) DUF258 PF03193.11 AIN99458.1 - 0.0078 15.4 0.0 0.02 14.0 0.0 1.8 1 1 0 1 1 1 1 Protein of unknown function, DUF258 AAA_16 PF13191.1 AIN99458.1 - 0.019 14.9 0.0 0.033 14.1 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain ABC_tran PF00005.22 AIN99458.1 - 0.02 15.1 0.2 0.12 12.6 0.1 1.9 1 1 0 1 1 1 0 ABC transporter AAA_29 PF13555.1 AIN99458.1 - 0.045 13.2 0.0 0.098 12.1 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain G-alpha PF00503.15 AIN99458.1 - 0.07 11.8 5.0 0.43 9.2 0.7 2.7 1 1 1 2 2 2 0 G-protein alpha subunit PduV-EutP PF10662.4 AIN99458.1 - 0.085 12.3 0.1 7.5 6.0 0.0 2.6 1 1 1 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_5 PF07728.9 AIN99458.1 - 0.14 11.8 0.0 0.37 10.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) DUF607 PF04678.8 AIN99460.1 - 4.2e-51 173.4 0.0 1.5e-50 171.5 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function, DUF607 Glyoxalase_4 PF13669.1 AIN99460.1 - 0.02 14.9 0.3 0.047 13.7 0.0 1.9 2 1 0 2 2 2 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily LRR_6 PF13516.1 AIN99461.1 - 8.9e-05 22.1 2.3 0.31 11.2 0.3 3.8 3 0 0 3 3 3 2 Leucine Rich repeat LRR_4 PF12799.2 AIN99461.1 - 0.0011 18.5 1.6 0.049 13.2 1.0 3.3 4 0 0 4 4 4 1 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 AIN99461.1 - 0.1 12.3 1.7 0.48 10.2 1.2 2.1 1 1 0 1 1 1 0 Leucine rich repeat LRR_1 PF00560.28 AIN99461.1 - 6.7 7.1 6.2 40 4.7 0.0 3.9 5 1 0 5 5 5 0 Leucine Rich Repeat Glutaredoxin PF00462.19 AIN99462.1 - 8.8e-14 51.2 0.2 1.2e-13 50.8 0.2 1.2 1 0 0 1 1 1 1 Glutaredoxin GST_N_3 PF13417.1 AIN99462.1 - 0.00021 21.4 0.0 0.00025 21.1 0.0 1.1 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Thioredoxin_3 PF13192.1 AIN99462.1 - 0.00077 19.2 0.1 0.001 18.8 0.1 1.3 1 0 0 1 1 1 1 Thioredoxin domain DSBA PF01323.15 AIN99462.1 - 0.0018 17.8 0.3 0.35 10.4 0.1 2.1 1 1 1 2 2 2 2 DSBA-like thioredoxin domain Thioredoxin_4 PF13462.1 AIN99462.1 - 0.016 15.2 0.6 0.82 9.6 0.0 2.1 1 1 0 2 2 2 0 Thioredoxin Thioredoxin_2 PF13098.1 AIN99462.1 - 0.042 14.0 0.7 0.18 12.0 0.5 1.9 1 1 0 1 1 1 0 Thioredoxin-like domain DUF836 PF05768.9 AIN99462.1 - 0.066 13.4 0.0 0.076 13.2 0.0 1.2 1 0 0 1 1 1 0 Glutaredoxin-like domain (DUF836) Zn_Tnp_IS1 PF03811.8 AIN99462.1 - 0.12 11.8 0.1 0.32 10.5 0.1 1.7 1 0 0 1 1 1 0 InsA N-terminal domain Beta_helix PF13229.1 AIN99463.1 - 4.2e-94 312.5 126.8 4.7e-16 58.9 6.4 17.1 9 5 6 15 15 15 15 Right handed beta helix region NosD PF05048.8 AIN99463.1 - 2.1e-76 256.1 57.1 3.9e-13 49.1 5.3 15.2 10 4 4 15 15 15 12 Periplasmic copper-binding protein (NosD) End3 PF12761.2 AIN99463.1 - 0.011 15.3 0.2 0.023 14.3 0.1 1.4 1 0 0 1 1 1 0 Actin cytoskeleton-regulatory complex protein END3 Cortex-I_coil PF09304.5 AIN99463.1 - 0.31 11.1 0.2 0.64 10.0 0.1 1.4 1 0 0 1 1 1 0 Cortexillin I, coiled coil FliJ PF02050.11 AIN99463.1 - 0.31 11.0 0.8 0.64 10.0 0.6 1.4 1 0 0 1 1 1 0 Flagellar FliJ protein CorA PF01544.13 AIN99463.1 - 0.76 8.7 0.3 2.9 6.8 0.2 1.9 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein SDH_alpha PF03313.10 AIN99464.1 - 0.041 12.9 0.0 0.079 11.9 0.0 1.4 1 0 0 1 1 1 0 Serine dehydratase alpha chain WD40 PF00400.27 AIN99467.1 - 0.00079 19.2 20.4 0.0061 16.4 0.0 6.0 6 0 0 6 6 6 3 WD domain, G-beta repeat DUF1126 PF06565.7 AIN99468.1 - 9.7e-42 140.1 0.2 2.4e-13 49.3 0.0 3.6 3 0 0 3 3 3 3 Repeat of unknown function (DUF1126) EF-hand_7 PF13499.1 AIN99468.1 - 1.8e-08 34.3 0.1 5.2e-07 29.7 0.0 3.1 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_8 PF13833.1 AIN99468.1 - 2.3e-05 23.9 1.5 0.058 13.0 0.0 3.6 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.27 AIN99468.1 - 8e-05 21.6 0.6 1.8 8.0 0.0 4.9 4 0 0 4 4 4 1 EF hand EF-hand_6 PF13405.1 AIN99468.1 - 0.0038 16.9 0.3 3.2 7.8 0.1 4.0 4 0 0 4 4 4 1 EF-hand domain Sep15_SelM PF08806.6 AIN99469.1 - 0.1 12.3 0.0 0.19 11.4 0.0 1.5 1 0 0 1 1 1 0 Sep15/SelM redox domain E1_dh PF00676.15 AIN99470.1 - 9.6e-53 178.8 0.0 1.6e-52 178.1 0.0 1.2 1 0 0 1 1 1 1 Dehydrogenase E1 component Transket_pyr PF02779.19 AIN99470.1 - 7.4e-48 162.3 0.0 1.3e-47 161.6 0.0 1.4 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain PIP5K PF01504.13 AIN99471.1 - 1.3e-65 221.0 0.0 2.1e-65 220.3 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase FYVE PF01363.16 AIN99471.1 - 9.4e-15 54.2 5.2 2.4e-14 52.9 3.6 1.8 1 0 0 1 1 1 1 FYVE zinc finger IBR PF01485.16 AIN99471.1 - 0.012 15.4 3.7 0.038 13.8 2.5 1.8 1 0 0 1 1 1 0 IBR domain DUF778 PF05608.7 AIN99472.1 - 2.8e-42 143.8 0.1 3.4e-42 143.6 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF778) LRAT PF04970.8 AIN99472.1 - 0.0075 16.2 0.1 0.01 15.8 0.1 1.2 1 0 0 1 1 1 1 Lecithin retinol acyltransferase Peptidase_C97 PF05903.9 AIN99472.1 - 0.13 12.0 0.1 0.2 11.4 0.0 1.4 1 0 0 1 1 1 0 PPPDE putative peptidase domain Pep3_Vps18 PF05131.9 AIN99473.1 - 1.8e-10 40.4 0.0 1.4e-06 27.8 0.0 3.2 3 0 0 3 3 3 2 Pep3/Vps18/deep orange family Clathrin PF00637.15 AIN99473.1 - 5.6e-08 32.4 0.0 2.6e-07 30.3 0.0 2.0 1 1 1 2 2 2 1 Region in Clathrin and VPS Vps39_2 PF10367.4 AIN99473.1 - 0.00035 20.7 0.2 0.00072 19.7 0.1 1.6 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 Clathrin_H_link PF13838.1 AIN99473.1 - 0.01 15.6 0.0 0.033 14.0 0.0 1.9 2 0 0 2 2 2 0 Clathrin-H-link VPS11_C PF12451.3 AIN99473.1 - 0.21 11.4 0.2 0.53 10.1 0.1 1.6 1 0 0 1 1 1 0 Vacuolar protein sorting protein 11 C terminal vATP-synt_E PF01991.13 AIN99473.1 - 0.22 10.7 0.3 0.62 9.3 0.0 1.9 2 0 0 2 2 2 0 ATP synthase (E/31 kDa) subunit zf-RING_5 PF14634.1 AIN99473.1 - 0.25 11.0 6.5 0.83 9.4 4.5 2.0 1 1 0 1 1 1 0 zinc-RING finger domain zf-RING_2 PF13639.1 AIN99473.1 - 6.4 6.6 15.9 0.54 10.1 6.5 2.7 2 1 1 3 3 3 0 Ring finger domain DUF1295 PF06966.7 AIN99474.1 - 3.2e-29 101.8 10.8 1.2e-28 100.0 7.5 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF1295) H_PPase PF03030.11 AIN99474.1 - 0.2 9.8 4.2 0.84 7.8 0.5 2.0 2 0 0 2 2 2 0 Inorganic H+ pyrophosphatase Acyl-CoA_dh_1 PF00441.19 AIN99475.1 - 7.5e-41 139.7 1.3 9.2e-41 139.4 0.3 1.6 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 AIN99475.1 - 2.4e-27 95.7 0.0 7.1e-27 94.2 0.0 1.8 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.14 AIN99475.1 - 2e-19 68.8 0.2 4.4e-19 67.7 0.1 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 AIN99475.1 - 1.3e-17 64.2 0.1 3.1e-17 63.0 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_ox_N PF14749.1 AIN99475.1 - 0.086 13.1 0.0 0.15 12.3 0.0 1.4 1 0 0 1 1 1 0 Acyl-coenzyme A oxidase N-terminal XRN_N PF03159.13 AIN99476.1 - 5.3e-22 78.3 0.0 9.1e-22 77.6 0.0 1.4 1 0 0 1 1 1 1 XRN 5'-3' exonuclease N-terminus ABC2_membrane_3 PF12698.2 AIN99478.1 - 1.1e-55 189.0 63.1 1.8e-35 122.6 17.4 3.3 2 2 0 2 2 2 2 ABC-2 family transporter protein ABC_tran PF00005.22 AIN99478.1 - 1.1e-52 177.9 0.0 3.9e-27 95.2 0.0 2.5 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 AIN99478.1 - 3.1e-16 60.1 0.0 2.7e-06 27.5 0.0 4.2 3 1 1 4 4 4 3 AAA domain AAA_15 PF13175.1 AIN99478.1 - 1.4e-05 24.3 0.0 0.48 9.3 0.0 3.9 4 0 0 4 4 4 1 AAA ATPase domain AAA_29 PF13555.1 AIN99478.1 - 2.3e-05 23.8 0.4 0.042 13.3 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain SbcCD_C PF13558.1 AIN99478.1 - 0.00014 21.7 0.0 0.15 11.9 0.0 3.7 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit DUF258 PF03193.11 AIN99478.1 - 0.00035 19.7 0.1 0.016 14.3 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function, DUF258 SMC_N PF02463.14 AIN99478.1 - 0.0004 19.6 0.0 5.2 6.2 0.0 3.6 3 1 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 AIN99478.1 - 0.0029 17.9 8.7 0.14 12.4 0.0 3.1 3 0 0 3 3 3 2 AAA domain SRP54 PF00448.17 AIN99478.1 - 0.004 16.6 0.8 0.76 9.1 0.0 2.6 3 0 0 3 3 3 1 SRP54-type protein, GTPase domain AAA_30 PF13604.1 AIN99478.1 - 0.0077 15.8 0.2 0.15 11.5 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_10 PF12846.2 AIN99478.1 - 0.013 14.9 0.0 0.43 9.9 0.0 2.4 2 0 0 2 2 2 0 AAA-like domain Zeta_toxin PF06414.7 AIN99478.1 - 0.015 14.3 0.3 9.2 5.2 0.0 3.2 3 0 0 3 3 3 0 Zeta toxin RNA_helicase PF00910.17 AIN99478.1 - 0.071 13.2 0.2 18 5.5 0.0 2.6 2 0 0 2 2 2 0 RNA helicase MobB PF03205.9 AIN99478.1 - 0.11 12.2 0.2 4.2 7.0 0.0 2.6 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_16 PF13191.1 AIN99478.1 - 0.12 12.3 0.1 1.7 8.5 0.0 2.5 2 0 0 2 2 2 0 AAA ATPase domain AAA_13 PF13166.1 AIN99478.1 - 1.1 7.6 1.3 14 3.9 0.1 2.2 2 0 0 2 2 2 0 AAA domain ABC2_membrane PF01061.19 AIN99478.1 - 7.2 5.7 56.7 0.012 14.8 11.8 3.8 5 0 0 5 5 5 0 ABC-2 type transporter TatD_DNase PF01026.16 AIN99480.1 - 1.1e-36 126.3 0.0 1.3e-36 126.0 0.0 1.1 1 0 0 1 1 1 1 TatD related DNase Amidohydro_2 PF04909.9 AIN99480.1 - 3e-07 30.2 0.0 0.0018 17.9 0.0 2.7 3 1 0 3 3 3 2 Amidohydrolase DUF2894 PF11445.3 AIN99482.1 - 0.016 15.5 0.8 0.03 14.5 0.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2894) CoA_binding_3 PF13727.1 AIN99484.1 - 0.037 13.8 0.3 0.082 12.7 0.2 1.5 1 0 0 1 1 1 0 CoA-binding domain AAA PF00004.24 AIN99486.1 - 5.1e-87 288.7 0.0 1.4e-47 161.1 0.0 2.3 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 AIN99486.1 - 6.5e-16 58.0 0.0 2.6e-08 33.2 0.0 2.3 2 0 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 AIN99486.1 - 1.2e-12 48.1 1.6 0.00015 21.8 0.0 4.4 3 2 2 5 5 4 2 AAA ATPase domain AAA_5 PF07728.9 AIN99486.1 - 1.6e-11 44.1 0.0 0.00011 21.9 0.0 3.6 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 AIN99486.1 - 8e-11 42.1 0.0 2.1e-05 24.5 0.0 2.7 2 1 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_22 PF13401.1 AIN99486.1 - 1.2e-10 41.5 0.1 0.0022 18.1 0.0 4.4 2 2 0 2 2 2 2 AAA domain AAA_17 PF13207.1 AIN99486.1 - 3.3e-09 37.5 0.0 0.0012 19.6 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_14 PF13173.1 AIN99486.1 - 4.2e-09 36.3 0.0 0.0014 18.5 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_33 PF13671.1 AIN99486.1 - 6.1e-09 35.8 0.0 0.0019 18.0 0.0 2.5 2 0 0 2 2 2 2 AAA domain Zeta_toxin PF06414.7 AIN99486.1 - 1.1e-08 34.4 0.0 2.5e-05 23.4 0.0 2.5 2 0 0 2 2 2 2 Zeta toxin AAA_19 PF13245.1 AIN99486.1 - 1.9e-07 30.7 0.8 0.018 14.8 0.0 2.7 2 0 0 2 2 2 2 Part of AAA domain IstB_IS21 PF01695.12 AIN99486.1 - 7.6e-07 28.7 0.0 0.028 13.8 0.0 2.4 2 0 0 2 2 2 2 IstB-like ATP binding protein RNA_helicase PF00910.17 AIN99486.1 - 8.5e-07 29.1 0.0 0.028 14.5 0.0 2.9 3 0 0 3 3 2 2 RNA helicase TIP49 PF06068.8 AIN99486.1 - 1.6e-05 23.8 0.0 0.12 11.0 0.0 2.2 2 0 0 2 2 2 2 TIP49 C-terminus AAA_25 PF13481.1 AIN99486.1 - 1.9e-05 24.1 2.7 1.5 8.1 0.0 4.0 2 2 1 4 4 4 2 AAA domain NACHT PF05729.7 AIN99486.1 - 2.1e-05 24.2 0.2 0.32 10.6 0.0 3.2 3 0 0 3 3 3 2 NACHT domain AAA_18 PF13238.1 AIN99486.1 - 2.9e-05 24.3 0.0 0.12 12.6 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_28 PF13521.1 AIN99486.1 - 3e-05 24.0 0.0 0.22 11.4 0.0 2.5 2 0 0 2 2 2 2 AAA domain Mg_chelatase PF01078.16 AIN99486.1 - 4.3e-05 22.7 0.1 0.044 12.9 0.0 2.5 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_3 PF07726.6 AIN99486.1 - 4.5e-05 23.0 0.0 0.37 10.3 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) ABC_tran PF00005.22 AIN99486.1 - 0.00016 21.9 0.0 0.32 11.2 0.0 2.8 2 1 0 2 2 2 1 ABC transporter AAA_24 PF13479.1 AIN99486.1 - 0.00029 20.4 0.1 0.095 12.2 0.0 2.4 2 0 0 2 2 2 1 AAA domain Sigma54_activat PF00158.21 AIN99486.1 - 0.00036 20.0 0.0 0.081 12.3 0.0 2.9 3 0 0 3 3 2 1 Sigma-54 interaction domain NB-ARC PF00931.17 AIN99486.1 - 0.00053 18.9 0.0 0.22 10.3 0.0 2.3 2 0 0 2 2 2 2 NB-ARC domain Sigma54_activ_2 PF14532.1 AIN99486.1 - 0.00091 19.2 0.0 0.03 14.3 0.0 2.6 2 0 0 2 2 2 1 Sigma-54 interaction domain NTPase_1 PF03266.10 AIN99486.1 - 0.0011 18.7 0.3 0.33 10.6 0.0 3.0 3 0 0 3 3 3 1 NTPase Vps4_C PF09336.5 AIN99486.1 - 0.0018 18.1 0.0 0.0052 16.6 0.0 1.7 1 0 0 1 1 1 1 Vps4 C terminal oligomerisation domain AAA_11 PF13086.1 AIN99486.1 - 0.0019 17.7 0.0 0.74 9.3 0.0 2.3 2 0 0 2 2 2 1 AAA domain Arch_ATPase PF01637.13 AIN99486.1 - 0.002 17.8 0.0 1.2 8.8 0.0 2.7 2 2 0 2 2 2 1 Archaeal ATPase Viral_helicase1 PF01443.13 AIN99486.1 - 0.0021 17.6 0.0 0.43 10.0 0.0 2.3 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase Bac_DnaA PF00308.13 AIN99486.1 - 0.0034 17.0 0.0 1.4 8.5 0.0 2.5 2 0 0 2 2 2 1 Bacterial dnaA protein UPF0079 PF02367.12 AIN99486.1 - 0.0037 16.8 0.0 3 7.4 0.0 2.4 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 Parvo_NS1 PF01057.12 AIN99486.1 - 0.012 14.4 0.1 0.38 9.5 0.0 2.1 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 DUF815 PF05673.8 AIN99486.1 - 0.013 14.4 0.0 2.5 6.9 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) SKI PF01202.17 AIN99486.1 - 0.044 13.6 0.0 0.42 10.4 0.0 2.2 2 0 0 2 2 2 0 Shikimate kinase Rad17 PF03215.10 AIN99486.1 - 0.047 12.3 0.0 0.25 9.9 0.0 2.0 2 0 0 2 2 2 0 Rad17 cell cycle checkpoint protein AAA_30 PF13604.1 AIN99486.1 - 0.089 12.3 0.1 20 4.7 0.0 3.0 4 0 0 4 4 3 0 AAA domain AAA_29 PF13555.1 AIN99486.1 - 0.11 11.9 0.0 5.7 6.5 0.0 2.4 2 0 0 2 2 2 0 P-loop containing region of AAA domain KaiC PF06745.8 AIN99486.1 - 0.12 11.4 0.1 2.5 7.1 0.0 2.6 2 1 1 3 3 3 0 KaiC ResIII PF04851.10 AIN99486.1 - 0.2 11.4 0.0 22 4.8 0.0 2.3 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit Aminotran_5 PF00266.14 AIN99487.1 - 1.5e-83 280.5 0.0 1.8e-83 280.3 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.16 AIN99487.1 - 7.7e-12 44.9 0.1 1.1e-11 44.4 0.0 1.1 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.12 AIN99487.1 - 0.0012 17.9 0.0 0.0017 17.4 0.0 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Pyridoxal_deC PF00282.14 AIN99487.1 - 0.0079 14.6 0.0 0.015 13.8 0.0 1.4 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain AAA PF00004.24 AIN99488.1 - 2.6e-37 127.9 0.0 2.5e-27 95.6 0.0 3.5 2 1 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 AIN99488.1 - 5.1e-13 49.2 1.2 1.9e-05 24.8 0.0 3.5 2 1 1 3 3 3 2 AAA domain AAA_17 PF13207.1 AIN99488.1 - 8.3e-10 39.5 0.0 2.6e-05 25.0 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.1 AIN99488.1 - 9.8e-09 34.8 0.3 0.00021 20.9 0.1 3.3 2 0 0 2 2 2 2 Part of AAA domain Mg_chelatase PF01078.16 AIN99488.1 - 6.4e-08 32.0 0.0 0.00074 18.7 0.0 2.6 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.12 AIN99488.1 - 9.5e-08 31.6 0.0 0.00043 19.7 0.0 2.4 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_16 PF13191.1 AIN99488.1 - 1.4e-07 31.6 10.0 0.0014 18.6 0.1 4.3 4 2 0 5 5 3 2 AAA ATPase domain AAA_2 PF07724.9 AIN99488.1 - 2.3e-07 30.8 0.0 0.0003 20.7 0.0 2.4 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_5 PF07728.9 AIN99488.1 - 2.3e-07 30.5 0.1 0.024 14.3 0.0 2.9 3 0 0 3 3 2 2 AAA domain (dynein-related subfamily) AAA_33 PF13671.1 AIN99488.1 - 6.1e-07 29.4 0.0 0.025 14.4 0.0 2.9 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.1 AIN99488.1 - 9.2e-07 29.2 0.0 0.0033 17.7 0.0 2.6 2 0 0 2 2 2 2 AAA domain ABC_tran PF00005.22 AIN99488.1 - 9.8e-07 29.1 0.0 0.0042 17.3 0.0 2.8 3 0 0 3 3 2 2 ABC transporter TIP49 PF06068.8 AIN99488.1 - 3.1e-06 26.1 0.0 0.029 13.0 0.0 2.2 2 0 0 2 2 2 2 TIP49 C-terminus AAA_14 PF13173.1 AIN99488.1 - 2.5e-05 24.1 0.0 0.013 15.4 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.1 AIN99488.1 - 3.2e-05 23.9 1.1 0.018 15.0 0.0 3.1 3 0 0 3 3 3 1 AAA domain NB-ARC PF00931.17 AIN99488.1 - 6.6e-05 21.9 0.1 0.15 10.9 0.0 3.1 2 1 1 3 3 3 1 NB-ARC domain RNA_helicase PF00910.17 AIN99488.1 - 6.7e-05 23.0 0.0 0.39 10.8 0.0 2.5 2 0 0 2 2 2 2 RNA helicase Sigma54_activat PF00158.21 AIN99488.1 - 0.00012 21.5 0.0 0.61 9.5 0.0 2.5 2 0 0 2 2 2 2 Sigma-54 interaction domain RuvB_N PF05496.7 AIN99488.1 - 0.0002 20.4 0.0 0.2 10.6 0.0 2.4 2 0 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus AAA_30 PF13604.1 AIN99488.1 - 0.0002 20.9 0.0 0.051 13.1 0.0 2.7 2 1 0 2 2 2 1 AAA domain NACHT PF05729.7 AIN99488.1 - 0.00031 20.4 0.0 0.52 9.9 0.0 3.4 3 1 0 3 3 2 1 NACHT domain AAA_24 PF13479.1 AIN99488.1 - 0.00037 20.1 0.0 0.74 9.3 0.0 2.4 2 0 0 2 2 2 2 AAA domain DUF2075 PF09848.4 AIN99488.1 - 0.00043 19.3 0.0 0.068 12.1 0.0 2.2 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) Sigma54_activ_2 PF14532.1 AIN99488.1 - 0.00044 20.2 0.0 0.11 12.5 0.0 2.6 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_25 PF13481.1 AIN99488.1 - 0.00077 18.9 0.7 0.29 10.4 0.1 3.9 3 1 1 4 4 3 1 AAA domain AAA_29 PF13555.1 AIN99488.1 - 0.0012 18.3 0.1 0.33 10.5 0.1 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_11 PF13086.1 AIN99488.1 - 0.0024 17.5 0.0 0.25 10.8 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_10 PF12846.2 AIN99488.1 - 0.0036 16.7 0.0 0.71 9.2 0.0 3.6 3 1 0 3 3 3 1 AAA-like domain NTPase_1 PF03266.10 AIN99488.1 - 0.0049 16.6 0.2 0.29 10.8 0.0 2.8 3 0 0 3 3 2 1 NTPase Zot PF05707.7 AIN99488.1 - 0.0056 16.1 0.0 0.12 11.7 0.0 2.7 3 0 0 3 3 3 1 Zonular occludens toxin (Zot) KTI12 PF08433.5 AIN99488.1 - 0.0061 15.8 0.0 3.3 6.8 0.0 2.3 2 0 0 2 2 2 1 Chromatin associated protein KTI12 Arch_ATPase PF01637.13 AIN99488.1 - 0.0099 15.5 0.0 0.85 9.2 0.0 2.4 2 0 0 2 2 2 1 Archaeal ATPase ArgK PF03308.11 AIN99488.1 - 0.02 13.7 0.3 0.082 11.6 0.1 1.9 2 0 0 2 2 2 0 ArgK protein Rad17 PF03215.10 AIN99488.1 - 0.023 13.4 0.0 0.13 10.9 0.0 1.9 2 0 0 2 2 2 0 Rad17 cell cycle checkpoint protein Zeta_toxin PF06414.7 AIN99488.1 - 0.05 12.7 0.0 8.1 5.4 0.0 2.5 2 0 0 2 2 2 0 Zeta toxin MMR_HSR1 PF01926.18 AIN99488.1 - 0.059 13.3 0.0 0.43 10.5 0.0 2.4 2 0 0 2 2 2 0 50S ribosome-binding GTPase PPV_E1_C PF00519.12 AIN99488.1 - 0.084 11.4 0.0 4.3 5.8 0.0 2.1 2 0 0 2 2 2 0 Papillomavirus helicase Parvo_NS1 PF01057.12 AIN99488.1 - 0.091 11.6 0.0 4.2 6.1 0.0 2.2 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 PhoH PF02562.11 AIN99488.1 - 0.1 11.7 0.0 7 5.8 0.0 2.3 2 0 0 2 2 2 0 PhoH-like protein KaiC PF06745.8 AIN99488.1 - 0.21 10.6 0.1 10 5.1 0.1 2.4 2 0 0 2 2 2 0 KaiC AAA_23 PF13476.1 AIN99488.1 - 0.21 11.8 0.1 3.1 8.0 0.0 2.2 2 0 0 2 2 2 0 AAA domain 6PF2K PF01591.13 AIN99488.1 - 0.31 10.0 0.0 14 4.6 0.0 2.2 2 0 0 2 2 2 0 6-phosphofructo-2-kinase TPR_12 PF13424.1 AIN99489.1 - 6.3e-11 42.0 30.5 0.067 13.1 1.9 10.5 9 2 1 10 10 10 4 Tetratricopeptide repeat TPR_14 PF13428.1 AIN99489.1 - 7.4e-11 41.6 43.2 0.83 10.4 0.0 16.2 13 6 6 19 19 19 3 Tetratricopeptide repeat TPR_11 PF13414.1 AIN99489.1 - 1.7e-09 37.1 33.0 0.0028 17.2 0.0 10.8 11 3 4 15 15 15 3 TPR repeat TPR_19 PF14559.1 AIN99489.1 - 6.8e-09 35.9 19.4 0.0044 17.3 0.0 10.3 11 1 1 12 12 12 2 Tetratricopeptide repeat TPR_1 PF00515.23 AIN99489.1 - 1.5e-07 30.7 2.1 0.57 9.8 0.1 8.0 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_2 PF07719.12 AIN99489.1 - 1.9e-06 27.3 18.9 35 4.6 0.3 12.1 13 0 0 13 13 13 0 Tetratricopeptide repeat TPR_17 PF13431.1 AIN99489.1 - 2.1e-06 27.4 12.7 0.5 10.7 0.0 8.1 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_7 PF13176.1 AIN99489.1 - 2.3e-05 23.8 18.5 0.052 13.3 0.1 9.2 10 0 0 10 10 10 2 Tetratricopeptide repeat TPR_16 PF13432.1 AIN99489.1 - 0.0028 18.2 50.1 0.095 13.3 0.1 11.7 12 1 1 13 13 13 3 Tetratricopeptide repeat EBP PF05241.7 AIN99490.1 - 1.5e-33 115.5 6.8 1.9e-33 115.1 4.7 1.0 1 0 0 1 1 1 1 Emopamil binding protein ABC2_membrane_2 PF12679.2 AIN99490.1 - 1.7 7.4 6.2 1.4 7.7 3.3 1.5 1 1 0 1 1 1 0 ABC-2 family transporter protein DUF2781 PF10914.3 AIN99490.1 - 5 6.8 11.0 6.7 6.4 7.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2781) MRP PF09387.5 AIN99492.1 - 1.1e-61 208.0 2.5 1.1e-61 208.0 1.7 1.9 2 0 0 2 2 2 1 Mitochondrial RNA binding protein MRP WGG PF10273.4 AIN99493.1 - 0.00091 19.2 1.0 0.0035 17.3 0.7 1.9 1 1 0 1 1 1 1 Pre-rRNA-processing protein TSR2 TPR_11 PF13414.1 AIN99495.1 - 3.1e-34 116.4 33.9 7.3e-12 44.7 1.9 7.1 7 0 0 7 7 7 6 TPR repeat TPR_16 PF13432.1 AIN99495.1 - 1e-29 102.5 25.2 1e-07 32.4 0.1 7.3 6 1 1 8 8 7 6 Tetratricopeptide repeat TPR_12 PF13424.1 AIN99495.1 - 2.7e-29 100.9 32.4 1.8e-06 27.7 0.6 8.2 4 3 2 7 7 7 6 Tetratricopeptide repeat TPR_2 PF07719.12 AIN99495.1 - 1.2e-23 81.0 43.0 0.0012 18.5 0.2 11.9 13 0 0 13 13 12 6 Tetratricopeptide repeat TPR_1 PF00515.23 AIN99495.1 - 2.2e-22 77.6 45.9 5.8e-05 22.5 0.6 11.6 12 0 0 12 12 12 6 Tetratricopeptide repeat TPR_19 PF14559.1 AIN99495.1 - 8.9e-21 74.0 26.1 3.5e-05 24.0 1.0 8.1 6 2 3 9 9 9 7 Tetratricopeptide repeat TPR_6 PF13174.1 AIN99495.1 - 3.6e-19 67.8 28.1 0.00082 19.6 0.0 11.3 12 0 0 12 12 11 4 Tetratricopeptide repeat TPR_7 PF13176.1 AIN99495.1 - 2e-15 55.2 26.5 0.032 14.0 0.0 10.1 11 0 0 11 11 10 4 Tetratricopeptide repeat TPR_14 PF13428.1 AIN99495.1 - 5.3e-15 54.5 17.2 0.0037 17.7 0.0 10.1 4 3 8 12 12 11 3 Tetratricopeptide repeat Apc3 PF12895.2 AIN99495.1 - 8.3e-12 45.0 31.8 0.0013 18.8 0.1 7.3 4 2 4 8 8 8 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.1 AIN99495.1 - 1.2e-11 43.5 34.4 0.014 15.1 0.4 10.2 11 0 0 11 11 11 4 Tetratricopeptide repeat TPR_17 PF13431.1 AIN99495.1 - 3.1e-09 36.3 27.0 0.0027 17.7 0.4 9.7 10 0 0 10 10 10 2 Tetratricopeptide repeat TPR_10 PF13374.1 AIN99495.1 - 5.7e-06 26.0 29.4 1.5 8.9 0.1 10.4 11 0 0 11 11 11 2 Tetratricopeptide repeat TPR_9 PF13371.1 AIN99495.1 - 7.2e-05 22.5 4.1 0.46 10.3 0.0 5.5 5 2 1 6 6 6 1 Tetratricopeptide repeat TPR_4 PF07721.9 AIN99495.1 - 0.00013 22.0 0.6 20 5.9 0.0 5.2 5 0 0 5 5 4 0 Tetratricopeptide repeat PPR PF01535.15 AIN99495.1 - 0.0012 18.7 12.2 1.9 8.6 0.0 7.2 8 0 0 8 8 6 2 PPR repeat PPR_3 PF13812.1 AIN99495.1 - 0.062 13.6 2.3 1.1e+02 3.4 0.0 5.3 5 0 0 5 5 5 0 Pentatricopeptide repeat domain Fis1_TPR_C PF14853.1 AIN99495.1 - 0.49 10.3 21.2 2.7 7.9 0.2 6.6 6 1 1 7 7 7 0 Fis1 C-terminal tetratricopeptide repeat JmjC PF02373.17 AIN99497.1 - 1e-10 41.8 4.4 5e-09 36.4 3.1 2.4 1 1 0 1 1 1 1 JmjC domain, hydroxylase Cupin_8 PF13621.1 AIN99497.1 - 0.0023 17.5 1.4 0.049 13.1 1.0 2.7 1 1 0 1 1 1 1 Cupin-like domain RAI16-like PF10257.4 AIN99498.1 - 8.8e-10 38.0 2.6 1.7e-09 37.0 0.2 2.5 2 1 0 2 2 2 1 Retinoic acid induced 16-like protein eIF-1a PF01176.14 AIN99499.1 - 0.043 13.2 0.0 0.098 12.0 0.0 1.6 1 0 0 1 1 1 0 Translation initiation factor 1A / IF-1 SpoIIE PF07228.7 AIN99500.1 - 8.1e-05 22.3 3.7 0.055 13.1 1.8 2.9 1 1 1 2 2 2 2 Stage II sporulation protein E (SpoIIE) PP2C_2 PF13672.1 AIN99500.1 - 0.00084 18.7 6.1 0.0034 16.8 2.7 2.5 2 1 0 2 2 2 1 Protein phosphatase 2C HMG-CoA_red PF00368.13 AIN99500.1 - 0.022 13.4 0.2 0.034 12.8 0.1 1.2 1 0 0 1 1 1 0 Hydroxymethylglutaryl-coenzyme A reductase zf-rbx1 PF12678.2 AIN99501.1 - 2.2e-09 37.2 8.3 4e-09 36.4 5.7 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_2 PF13639.1 AIN99501.1 - 4.7e-08 32.7 15.1 8.1e-08 31.9 10.5 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 AIN99501.1 - 3.6e-06 26.8 11.2 6.8e-06 26.0 7.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 AIN99501.1 - 1.2e-05 25.0 5.7 2.7e-05 23.8 4.0 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4 PF00097.20 AIN99501.1 - 0.0021 17.6 11.3 0.0038 16.8 7.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 AIN99501.1 - 0.017 14.8 12.7 0.029 14.1 8.8 1.4 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4_3 PF13920.1 AIN99501.1 - 0.041 13.5 11.0 0.073 12.7 7.6 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) RINGv PF12906.2 AIN99501.1 - 5 7.2 9.8 11 6.1 6.8 1.6 1 0 0 1 1 1 0 RING-variant domain IF-2B PF01008.12 AIN99502.1 - 7.6e-34 116.9 0.0 1.4e-33 116.1 0.0 1.5 1 0 0 1 1 1 1 Initiation factor 2 subunit family HC2 PF07382.6 AIN99505.1 - 0.0011 18.8 71.1 0.0014 18.5 49.3 1.2 1 0 0 1 1 1 1 Histone H1-like nucleoprotein HC2 WD40 PF00400.27 AIN99506.1 - 7.2e-23 79.5 19.2 3.1e-06 26.8 0.0 6.1 7 0 0 7 7 7 5 WD domain, G-beta repeat Cpn60_TCP1 PF00118.19 AIN99507.1 - 2e-136 455.4 11.6 2.3e-136 455.2 8.0 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Cation_efflux PF01545.16 AIN99508.1 - 3.5e-58 196.9 9.2 3.5e-58 196.9 6.3 2.4 2 0 0 2 2 2 1 Cation efflux family NDUF_C2 PF06374.6 AIN99508.1 - 0.081 12.9 0.3 6.6 6.7 0.0 2.9 2 1 1 3 3 3 0 NADH-ubiquinone oxidoreductase subunit b14.5b (NDUFC2) UCH PF00443.24 AIN99509.1 - 6.8e-53 179.5 2.1 1e-52 178.9 1.4 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 AIN99509.1 - 3.3e-22 79.2 1.1 6e-22 78.4 0.8 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DUF2197 PF09963.4 AIN99509.1 - 0.039 13.9 0.1 0.16 11.9 0.1 2.0 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2197) DZR PF12773.2 AIN99509.1 - 0.16 11.8 7.1 1.8 8.4 5.0 2.2 1 1 0 1 1 1 0 Double zinc ribbon PhnA_Zn_Ribbon PF08274.7 AIN99509.1 - 0.35 10.7 4.5 2.5 7.9 0.2 2.5 2 0 0 2 2 2 0 PhnA Zinc-Ribbon ParA PF10609.4 AIN99509.1 - 0.6 10.0 3.1 17 5.3 0.2 3.3 3 0 0 3 3 3 0 ParA/MinD ATPase like zinc-ribbons_6 PF07191.7 AIN99509.1 - 0.88 9.4 6.6 12 5.8 0.7 3.2 3 0 0 3 3 3 0 zinc-ribbons CpXC PF14353.1 AIN99509.1 - 2.1 8.2 7.3 2.7 7.9 0.2 3.4 3 1 1 4 4 4 0 CpXC protein DUF2296 PF10058.4 AIN99509.1 - 3.6 7.4 7.4 7.5 6.3 0.3 3.0 3 0 0 3 3 3 0 Predicted integral membrane metal-binding protein (DUF2296) zf-RING_3 PF14369.1 AIN99509.1 - 5.8 7.0 7.5 28 4.8 0.1 3.8 3 0 0 3 3 3 0 zinc-finger Ribonucleas_3_3 PF14622.1 AIN99511.1 - 7.9e-07 29.0 0.0 1.5e-05 24.9 0.0 2.0 1 1 0 1 1 1 1 Ribonuclease-III-like Ribonuclease_3 PF00636.21 AIN99511.1 - 0.0075 16.7 0.0 0.011 16.1 0.0 1.3 1 0 0 1 1 1 1 Ribonuclease III domain DUF397 PF04149.7 AIN99511.1 - 0.092 12.3 0.0 0.18 11.4 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF397) LRR_6 PF13516.1 AIN99512.1 - 3e-19 66.8 11.7 0.062 13.3 0.0 9.0 9 0 0 9 9 9 6 Leucine Rich repeat LRR_4 PF12799.2 AIN99512.1 - 6.8e-12 44.7 3.1 0.0035 16.9 0.1 5.9 4 2 3 7 7 7 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 AIN99512.1 - 9.5e-08 31.0 5.3 4.4 7.7 0.0 8.4 9 1 0 9 9 9 2 Leucine Rich Repeat LRR_8 PF13855.1 AIN99512.1 - 1e-05 25.1 0.8 0.15 11.7 0.2 4.8 3 3 0 3 3 3 2 Leucine rich repeat LRR_7 PF13504.1 AIN99512.1 - 5.5e-05 22.7 7.1 20 5.9 0.0 7.7 9 0 0 9 9 9 1 Leucine rich repeat KH_1 PF00013.24 AIN99513.1 - 1.1e-05 25.0 0.0 2e-05 24.1 0.0 1.5 1 0 0 1 1 1 1 KH domain zf-CCCH PF00642.19 AIN99513.1 - 0.00077 19.0 4.0 0.0025 17.4 2.8 1.9 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) SAM_2 PF07647.12 AIN99513.1 - 0.029 14.2 0.0 0.078 12.8 0.0 1.8 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) Helicase_C PF00271.26 AIN99513.1 - 0.1 12.4 0.1 1.3 8.9 0.0 2.6 1 1 0 1 1 1 0 Helicase conserved C-terminal domain zf-CCCH_2 PF14608.1 AIN99513.1 - 0.1 12.6 1.2 0.23 11.5 0.8 1.5 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type tRNA-synt_1d PF00750.14 AIN99514.1 - 6.7e-91 304.7 0.1 3.7e-52 177.2 0.0 2.1 2 0 0 2 2 2 2 tRNA synthetases class I (R) DALR_1 PF05746.10 AIN99514.1 - 6.5e-27 93.8 3.5 5.1e-26 90.9 0.6 2.8 2 0 0 2 2 2 1 DALR anticodon binding domain Arg_tRNA_synt_N PF03485.11 AIN99514.1 - 1.1e-12 48.2 0.3 4.9e-12 46.2 0.2 2.2 1 0 0 1 1 1 1 Arginyl tRNA synthetase N terminal domain Ribosomal_L17 PF01196.14 AIN99514.1 - 0.033 14.7 0.1 0.15 12.6 0.0 2.1 2 0 0 2 2 2 0 Ribosomal protein L17 Cupin_8 PF13621.1 AIN99515.1 - 8.8e-18 64.7 0.4 2.8e-17 63.0 0.0 2.1 2 1 0 2 2 2 1 Cupin-like domain JmjC PF02373.17 AIN99515.1 - 2.5e-11 43.8 0.1 5.6e-11 42.6 0.0 1.7 1 0 0 1 1 1 1 JmjC domain, hydroxylase Cupin_4 PF08007.7 AIN99515.1 - 1.5e-05 24.4 0.0 2.7e-05 23.5 0.0 1.5 1 1 0 1 1 1 1 Cupin superfamily protein F-box PF00646.28 AIN99515.1 - 0.00083 18.9 0.3 0.0031 17.1 0.2 1.9 2 0 0 2 2 2 1 F-box domain Cupin_2 PF07883.6 AIN99515.1 - 0.012 15.1 0.0 0.034 13.6 0.0 1.7 1 0 0 1 1 1 0 Cupin domain F-box-like PF12937.2 AIN99515.1 - 0.039 13.6 0.5 0.09 12.5 0.4 1.6 1 0 0 1 1 1 0 F-box-like PknH_C PF14032.1 AIN99515.1 - 0.3 10.6 5.2 0.039 13.5 0.7 1.6 2 0 0 2 2 2 0 PknH-like extracellular domain Mo25 PF08569.6 AIN99516.1 - 0.091 11.7 0.3 0.27 10.2 0.1 1.5 1 1 0 1 1 1 0 Mo25-like DUF3482 PF11981.3 AIN99517.1 - 0.042 13.0 0.2 0.065 12.4 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3482) Pkinase PF00069.20 AIN99520.1 - 1.7e-58 197.8 0.0 2.9e-58 197.0 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AIN99520.1 - 9.1e-43 146.1 0.0 1.5e-42 145.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 AIN99520.1 - 0.0037 16.2 0.0 0.0083 15.1 0.0 1.5 1 1 0 1 1 1 1 Kinase-like APH PF01636.18 AIN99520.1 - 0.0071 16.1 0.0 0.021 14.5 0.0 1.8 1 1 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.17 AIN99520.1 - 0.061 12.6 0.0 0.28 10.5 0.0 1.9 1 1 1 2 2 2 0 RIO1 family Seadorna_VP7 PF07387.6 AIN99520.1 - 0.56 8.9 0.0 0.97 8.2 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Ribosomal_L10 PF00466.15 AIN99521.1 - 3.3e-24 84.7 0.1 9e-24 83.3 0.1 1.7 2 0 0 2 2 2 1 Ribosomal protein L10 Ribosomal_60s PF00428.14 AIN99521.1 - 7.1e-12 45.5 7.7 7.1e-12 45.5 5.3 2.5 3 1 1 4 4 4 1 60s Acidic ribosomal protein DUF1719 PF08224.6 AIN99522.1 - 0.0081 15.2 0.0 0.01 14.9 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1719) Choline_kinase PF01633.15 AIN99524.1 - 2.7e-22 79.4 0.1 1.5e-21 76.9 0.1 2.0 1 1 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.18 AIN99524.1 - 8.1e-11 42.1 0.1 2.9e-10 40.3 0.0 2.0 1 1 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.15 AIN99524.1 - 0.0061 15.7 0.1 0.01 14.9 0.0 1.5 1 0 0 1 1 1 1 Ecdysteroid kinase Pkinase PF00069.20 AIN99524.1 - 0.036 13.1 0.1 0.058 12.5 0.0 1.2 1 0 0 1 1 1 0 Protein kinase domain AAA_4 PF04326.9 AIN99525.1 - 0.0013 18.9 0.0 0.0024 18.0 0.0 1.4 1 0 0 1 1 1 1 Divergent AAA domain Prenyltrans_2 PF13249.1 AIN99525.1 - 0.031 14.6 1.0 0.11 12.9 0.4 2.2 2 0 0 2 2 2 0 Prenyltransferase-like Snf7 PF03357.16 AIN99526.1 - 1.6e-32 112.2 35.9 2.9e-32 111.4 24.9 1.5 1 1 0 1 1 1 1 Snf7 DUF1824 PF08854.5 AIN99526.1 - 1.3 8.6 5.6 1.5 8.4 0.4 2.6 2 1 1 3 3 3 0 Domain of unknown function (DUF1824) Band_7 PF01145.20 AIN99526.1 - 1.8 8.4 7.5 0.31 10.9 0.8 2.2 1 1 0 2 2 2 0 SPFH domain / Band 7 family CENP-Q PF13094.1 AIN99526.1 - 4.1 7.4 15.7 0.6 10.1 6.4 2.3 1 1 1 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit CBF PF03914.12 AIN99527.1 - 4.2e-34 117.3 0.8 4.2e-34 117.3 0.6 2.3 2 0 0 2 2 2 1 CBF/Mak21 family DUF2773 PF10971.3 AIN99527.1 - 0.0043 16.9 0.0 0.0097 15.8 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2773) Rpn3_C PF08375.6 AIN99528.1 - 4.9e-22 78.1 1.0 4.9e-22 78.1 0.7 2.1 3 0 0 3 3 3 1 Proteasome regulatory subunit C-terminal PCI PF01399.22 AIN99528.1 - 4.3e-18 65.5 0.1 8.1e-18 64.6 0.1 1.5 1 0 0 1 1 1 1 PCI domain TPR_2 PF07719.12 AIN99528.1 - 0.061 13.2 0.8 0.18 11.7 0.6 1.9 1 0 0 1 1 1 0 Tetratricopeptide repeat PCI_Csn8 PF10075.4 AIN99528.1 - 0.087 12.5 0.0 0.23 11.2 0.0 1.8 2 0 0 2 2 2 0 COP9 signalosome, subunit CSN8 PSD5 PF07637.6 AIN99528.1 - 0.18 11.8 1.6 12 6.0 0.1 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF1595) cNMP_binding PF00027.24 AIN99529.1 - 2.4e-15 56.0 0.0 8.8e-09 35.0 0.0 3.8 4 1 0 4 4 4 2 Cyclic nucleotide-binding domain DUF2815 PF10991.3 AIN99530.1 - 0.076 12.5 0.0 0.14 11.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2815) ESR1_C PF12743.2 AIN99530.1 - 3.3 7.3 9.2 3.2 7.3 0.1 3.3 2 0 0 2 2 2 0 Oestrogen-type nuclear receptor final C-terminal DUF543 PF04418.7 AIN99534.1 - 3.4e-22 78.1 0.0 4.1e-22 77.9 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF543) TctA PF01970.11 AIN99534.1 - 0.004 15.6 0.1 0.049 12.0 0.0 1.9 1 1 1 2 2 2 2 Tripartite tricarboxylate transporter TctA family RNA_pol_L_2 PF13656.1 AIN99535.1 - 2e-19 68.7 0.0 2.7e-19 68.3 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.19 AIN99535.1 - 9.4e-08 31.0 0.0 1.9e-07 30.1 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain DAGAT PF03982.8 AIN99536.1 - 6.5e-34 116.9 0.0 1.1e-33 116.2 0.0 1.2 1 0 0 1 1 1 1 Diacylglycerol acyltransferase His_Phos_1 PF00300.17 AIN99537.1 - 0.026 14.6 0.2 0.081 13.0 0.1 1.8 2 0 0 2 2 2 0 Histidine phosphatase superfamily (branch 1) Aa_trans PF01490.13 AIN99538.1 - 3.3e-58 197.1 28.2 3.7e-58 196.9 19.6 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.8 AIN99538.1 - 1.1e-10 40.9 7.1 1.1e-10 40.9 4.9 1.6 2 0 0 2 2 2 1 Tryptophan/tyrosine permease family DUF4231 PF14015.1 AIN99538.1 - 7.8 6.5 14.0 3.9 7.4 1.2 3.7 3 1 0 3 3 3 0 Protein of unknown function (DUF4231) HC2 PF07382.6 AIN99540.1 - 0.1 12.4 41.6 0.11 12.3 28.9 1.0 1 0 0 1 1 1 0 Histone H1-like nucleoprotein HC2 IF4E PF01652.13 AIN99541.1 - 1.2e-50 171.2 0.6 1.4e-50 171.0 0.4 1.0 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E WD40 PF00400.27 AIN99542.1 - 1.4e-14 53.2 0.1 0.0029 17.4 0.0 5.7 6 0 0 6 6 6 4 WD domain, G-beta repeat eIF2A PF08662.6 AIN99542.1 - 0.034 13.8 0.0 1.6 8.4 0.0 3.0 3 0 0 3 3 3 0 Eukaryotic translation initiation factor eIF2A BRO1 PF03097.13 AIN99543.1 - 2.6e-66 223.9 1.3 2.6e-66 223.9 0.9 2.6 2 1 0 2 2 2 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.1 AIN99543.1 - 2.5e-42 144.8 8.4 2.5e-42 144.8 5.8 2.3 1 1 1 2 2 2 1 ALIX V-shaped domain binding to HIV MIT PF04212.13 AIN99543.1 - 0.0015 18.4 3.8 0.01 15.7 0.0 3.8 3 0 0 3 3 3 1 MIT (microtubule interacting and transport) domain PAT1 PF09770.4 AIN99543.1 - 0.018 13.3 38.9 0.026 12.7 27.0 1.3 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF3964 PF13107.1 AIN99543.1 - 0.053 13.7 0.0 0.16 12.2 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3964) TPR_1 PF00515.23 AIN99543.1 - 0.082 12.5 0.8 0.26 10.9 0.1 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat PMC2NT PF08066.7 AIN99543.1 - 0.13 12.5 6.0 2.2 8.6 0.0 3.6 3 0 0 3 3 3 0 PMC2NT (NUC016) domain TPR_11 PF13414.1 AIN99543.1 - 0.37 10.4 2.5 4.5 7.0 0.1 3.2 4 0 0 4 4 4 0 TPR repeat Strumpellin PF10266.4 AIN99545.1 - 0 1451.3 0.0 0 1451.1 0.0 1.0 1 0 0 1 1 1 1 Hereditary spastic paraplegia protein strumpellin ThiF PF00899.16 AIN99546.1 - 9.4e-44 148.5 0.1 1.6e-43 147.8 0.1 1.3 1 0 0 1 1 1 1 ThiF family MoeZ_MoeB PF05237.8 AIN99546.1 - 1.3e-29 101.6 0.1 3.3e-29 100.2 0.1 1.8 1 0 0 1 1 1 1 MoeZ/MoeB domain Rhodanese PF00581.15 AIN99546.1 - 2.9e-07 30.8 0.0 6.4e-07 29.7 0.0 1.6 1 0 0 1 1 1 1 Rhodanese-like domain Shikimate_DH PF01488.15 AIN99546.1 - 0.0024 17.9 0.1 0.018 15.1 0.1 2.1 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase Saccharop_dh PF03435.13 AIN99546.1 - 0.0043 16.0 0.3 0.0063 15.5 0.2 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase 3HCDH_N PF02737.13 AIN99546.1 - 0.026 14.1 0.1 0.053 13.1 0.0 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pea-VEAacid PF08111.6 AIN99546.1 - 0.031 14.3 0.0 0.076 13.1 0.0 1.7 1 0 0 1 1 1 0 Pea-VEAacid family DapB_N PF01113.15 AIN99546.1 - 0.12 12.3 0.0 0.27 11.1 0.0 1.6 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus LRR_4 PF12799.2 AIN99548.1 - 7.5e-06 25.4 0.3 3e-05 23.5 0.2 1.9 2 0 0 2 2 2 1 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 AIN99548.1 - 0.0012 18.5 1.8 0.0027 17.4 1.2 1.7 1 1 0 1 1 1 1 Leucine rich repeat zf-CCCH_2 PF14608.1 AIN99548.1 - 0.0057 16.6 2.3 0.013 15.4 1.6 1.7 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type LRR_9 PF14580.1 AIN99548.1 - 0.014 14.9 0.0 0.029 13.9 0.0 1.5 1 0 0 1 1 1 0 Leucine-rich repeat LRR_7 PF13504.1 AIN99548.1 - 0.025 14.7 0.5 23 5.7 0.0 3.4 3 0 0 3 3 3 0 Leucine rich repeat LRR_1 PF00560.28 AIN99548.1 - 0.067 13.2 0.6 12 6.4 0.0 3.1 3 0 0 3 3 3 0 Leucine Rich Repeat ABC2_membrane PF01061.19 AIN99549.1 - 0.0021 17.2 14.6 0.0021 17.2 10.1 1.9 2 0 0 2 2 2 1 ABC-2 type transporter ABC_tran PF00005.22 AIN99549.1 - 0.12 12.6 0.0 0.23 11.7 0.0 1.4 1 0 0 1 1 1 0 ABC transporter eRF1_2 PF03464.10 AIN99550.1 - 4e-40 137.2 0.0 9.8e-40 135.9 0.0 1.7 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.10 AIN99550.1 - 5.5e-37 126.5 1.5 9e-37 125.7 0.2 2.0 2 0 0 2 2 2 1 eRF1 domain 3 eRF1_1 PF03463.10 AIN99550.1 - 1.8e-23 82.5 0.1 3.3e-23 81.7 0.1 1.4 1 0 0 1 1 1 1 eRF1 domain 1 BAR PF03114.13 AIN99551.1 - 0.004 16.7 10.3 0.014 14.9 7.1 1.8 1 1 0 1 1 1 1 BAR domain Vps5 PF09325.5 AIN99551.1 - 0.05 12.8 9.3 0.39 9.9 6.4 2.1 1 1 0 1 1 1 0 Vps5 C terminal like STAT_alpha PF01017.15 AIN99551.1 - 0.077 12.7 3.2 0.22 11.2 2.2 1.7 1 0 0 1 1 1 0 STAT protein, all-alpha domain Fer2_3 PF13085.1 AIN99551.1 - 0.094 12.5 0.4 0.24 11.2 0.3 1.7 1 1 0 1 1 1 0 2Fe-2S iron-sulfur cluster binding domain RHD3 PF05879.7 AIN99551.1 - 0.13 10.1 6.8 0.17 9.7 4.7 1.0 1 0 0 1 1 1 0 Root hair defective 3 GTP-binding protein (RHD3) DUF2203 PF09969.4 AIN99551.1 - 2.2 8.5 5.9 2.7 8.2 1.7 2.5 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2203) GAS PF13851.1 AIN99551.1 - 2.7 7.1 16.3 1.9 7.6 7.0 2.5 3 0 0 3 3 3 0 Growth-arrest specific micro-tubule binding DUF1154 PF06631.6 AIN99551.1 - 3.4 7.4 16.6 6 6.6 4.4 3.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1154) Dala_Dala_lig_N PF01820.16 AIN99551.1 - 4.4 7.6 5.4 7.3 6.9 1.8 2.2 1 1 0 2 2 2 0 D-ala D-ala ligase N-terminus DHC_N2 PF08393.8 AIN99552.1 - 3.4e-106 355.1 0.3 3.4e-106 355.1 0.2 3.4 4 0 0 4 4 3 1 Dynein heavy chain, N-terminal region 2 Dynein_heavy PF03028.10 AIN99552.1 - 9.7e-105 351.1 0.8 1.4e-104 350.6 0.0 1.7 2 0 0 2 2 1 1 Dynein heavy chain and region D6 of dynein motor AAA_6 PF12774.2 AIN99552.1 - 1.4e-79 266.8 0.0 3.3e-79 265.6 0.0 1.6 1 0 0 1 1 1 1 Hydrolytic ATP binding site of dynein motor region D1 AAA_9 PF12781.2 AIN99552.1 - 1.1e-34 119.2 0.4 2.7e-34 118.0 0.3 1.7 1 0 0 1 1 1 1 ATP-binding dynein motor region D5 AAA_5 PF07728.9 AIN99552.1 - 3.4e-31 107.8 0.0 3.7e-19 68.8 0.0 5.8 4 1 0 4 4 4 3 AAA domain (dynein-related subfamily) AAA_8 PF12780.2 AIN99552.1 - 1.5e-28 99.5 0.0 1.8e-27 96.0 0.0 2.6 2 0 0 2 2 2 1 P-loop containing dynein motor region D4 MT PF12777.2 AIN99552.1 - 2.1e-24 85.9 5.9 4.2e-24 84.9 4.1 1.5 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_7 PF12775.2 AIN99552.1 - 1.5e-18 66.8 0.3 4.6e-17 61.9 0.0 2.8 3 0 0 3 3 3 1 P-loop containing dynein motor region D3 AAA_16 PF13191.1 AIN99552.1 - 4.2e-13 49.6 10.4 0.0051 16.8 0.0 7.5 7 2 1 9 9 6 3 AAA ATPase domain AAA_22 PF13401.1 AIN99552.1 - 1.8e-12 47.4 0.0 0.032 14.3 0.0 6.4 5 0 0 5 5 5 3 AAA domain AAA PF00004.24 AIN99552.1 - 7.1e-10 39.1 0.1 0.15 12.2 0.0 6.3 6 0 0 6 6 5 2 ATPase family associated with various cellular activities (AAA) DUF258 PF03193.11 AIN99552.1 - 4.3e-07 29.2 0.0 0.00061 19.0 0.0 2.8 2 0 0 2 2 2 2 Protein of unknown function, DUF258 ABC_tran PF00005.22 AIN99552.1 - 6.8e-07 29.6 0.1 0.00096 19.4 0.0 4.5 3 0 0 3 3 3 1 ABC transporter AAA_17 PF13207.1 AIN99552.1 - 7.3e-07 30.0 0.1 0.0031 18.3 0.0 4.3 4 0 0 4 4 3 1 AAA domain AAA_29 PF13555.1 AIN99552.1 - 1e-05 24.9 0.0 0.0093 15.4 0.0 3.7 3 0 0 3 3 3 1 P-loop containing region of AAA domain RNA_helicase PF00910.17 AIN99552.1 - 1.3e-05 25.3 0.0 1.4 9.0 0.0 4.9 5 0 0 5 5 5 1 RNA helicase Zeta_toxin PF06414.7 AIN99552.1 - 5.4e-05 22.3 0.1 0.071 12.1 0.0 3.7 3 0 0 3 3 3 1 Zeta toxin AAA_33 PF13671.1 AIN99552.1 - 0.00012 21.9 0.2 0.029 14.2 0.0 4.2 4 0 0 4 4 3 1 AAA domain AAA_18 PF13238.1 AIN99552.1 - 0.00065 20.0 0.5 0.039 14.2 0.0 3.6 3 0 0 3 3 2 1 AAA domain AAA_14 PF13173.1 AIN99552.1 - 0.0014 18.5 0.0 5.8 6.8 0.0 4.9 6 0 0 6 6 4 0 AAA domain ATG16 PF08614.6 AIN99552.1 - 0.0027 17.5 3.1 0.0027 17.5 2.2 4.9 4 0 0 4 4 3 2 Autophagy protein 16 (ATG16) Arch_ATPase PF01637.13 AIN99552.1 - 0.0031 17.2 3.8 0.31 10.6 0.0 3.7 3 0 0 3 3 2 1 Archaeal ATPase Miro PF08477.8 AIN99552.1 - 0.0032 17.9 0.0 3.5 8.1 0.0 3.3 2 0 0 2 2 2 1 Miro-like protein AAA_28 PF13521.1 AIN99552.1 - 0.0037 17.2 6.2 0.013 15.5 0.0 4.3 4 0 0 4 4 3 1 AAA domain AAA_21 PF13304.1 AIN99552.1 - 0.012 15.6 0.0 0.03 14.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain MobB PF03205.9 AIN99552.1 - 0.036 13.7 0.4 0.31 10.7 0.1 2.7 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_24 PF13479.1 AIN99552.1 - 0.055 13.0 1.4 7.4 6.0 0.0 3.3 3 0 0 3 3 3 0 AAA domain SMC_N PF02463.14 AIN99552.1 - 0.071 12.3 0.0 6.2 5.9 0.0 2.6 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain Reo_sigmaC PF04582.7 AIN99552.1 - 0.17 11.0 4.7 2.5 7.1 0.3 3.4 3 0 0 3 3 3 0 Reovirus sigma C capsid protein AAA_15 PF13175.1 AIN99552.1 - 4.9 6.0 0.0 13 4.7 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain AAA_13 PF13166.1 AIN99552.1 - 6.1 5.1 28.6 3 6.1 0.8 4.8 4 1 1 5 5 5 0 AAA domain TBCC PF07986.7 AIN99553.1 - 2.2e-25 88.3 4.8 1.1e-18 66.7 4.8 2.4 2 0 0 2 2 2 2 Tubulin binding cofactor C Pkinase PF00069.20 AIN99554.1 - 2.6e-30 105.4 0.0 2e-28 99.2 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AIN99554.1 - 2.5e-10 39.8 0.0 5.7e-09 35.4 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 AIN99554.1 - 0.00013 21.8 0.2 0.00027 20.7 0.1 1.7 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 AIN99554.1 - 0.00062 18.8 0.1 0.001 18.1 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 AIN99554.1 - 0.00093 18.5 0.2 0.0024 17.2 0.1 1.6 2 0 0 2 2 2 1 RIO1 family Choline_kinase PF01633.15 AIN99554.1 - 0.13 11.8 0.0 0.22 11.0 0.0 1.4 1 1 0 1 1 1 0 Choline/ethanolamine kinase Pkinase PF00069.20 AIN99556.1 - 4.6e-39 134.1 0.0 6.9e-39 133.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AIN99556.1 - 1.5e-15 57.0 0.0 2.3e-15 56.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pox_ser-thr_kin PF05445.6 AIN99556.1 - 1.4 7.6 0.0 2.1 7.0 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase PEPCK_ATP PF01293.15 AIN99557.1 - 1.1e-197 657.2 0.0 1.3e-197 657.0 0.0 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase AAA_33 PF13671.1 AIN99557.1 - 0.045 13.6 0.0 0.19 11.5 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.1 AIN99557.1 - 0.082 12.4 0.1 0.22 11.0 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain CENP-F_leu_zip PF10473.4 AIN99558.1 - 0.0099 15.7 0.6 0.0099 15.7 0.4 6.4 4 2 1 5 5 5 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Phage_GP20 PF06810.6 AIN99558.1 - 0.014 14.8 0.9 0.014 14.8 0.6 5.2 4 2 1 5 5 5 0 Phage minor structural protein GP20 Fumble PF03630.9 AIN99558.1 - 0.075 11.8 0.3 0.18 10.6 0.2 1.5 1 0 0 1 1 1 0 Fumble IncA PF04156.9 AIN99558.1 - 0.092 12.3 52.2 0.015 14.8 9.7 5.4 4 1 1 5 5 5 0 IncA protein PLAC9 PF15205.1 AIN99558.1 - 0.33 11.2 3.2 2.1 8.7 0.1 3.3 2 0 0 2 2 2 0 Placenta-specific protein 9 DUF1759 PF03564.10 AIN99558.1 - 1.2 8.9 8.0 0.17 11.6 0.1 3.3 4 0 0 4 4 4 0 Protein of unknown function (DUF1759) BLOC1_2 PF10046.4 AIN99558.1 - 1.8 8.7 19.1 4.2 7.5 0.5 5.5 4 1 1 5 5 5 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF2935 PF11155.3 AIN99558.1 - 5.2 7.1 6.8 60 3.7 2.9 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF2935) TMF_DNA_bd PF12329.3 AIN99559.1 - 0.0069 16.1 2.1 0.0069 16.1 1.5 9.1 9 2 0 9 9 9 2 TATA element modulatory factor 1 DNA binding CENP-F_leu_zip PF10473.4 AIN99559.1 - 0.92 9.3 81.0 0.38 10.6 1.8 7.7 3 2 4 7 7 7 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 GAS PF13851.1 AIN99559.1 - 1.9 7.6 63.8 0.0074 15.4 14.2 5.6 3 2 2 5 5 5 0 Growth-arrest specific micro-tubule binding YchF-GTPase_C PF06071.8 AIN99560.1 - 2.1e-20 72.2 0.1 4.4e-20 71.2 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF933) MMR_HSR1 PF01926.18 AIN99560.1 - 1.2e-18 67.1 0.0 2.7e-18 66.0 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 AIN99560.1 - 2.8e-07 29.9 0.0 7.2e-07 28.6 0.0 1.7 2 0 0 2 2 2 1 Ferrous iron transport protein B TGS PF02824.16 AIN99560.1 - 0.00086 19.0 0.0 0.0019 18.0 0.0 1.5 1 0 0 1 1 1 1 TGS domain ArgK PF03308.11 AIN99560.1 - 0.079 11.7 0.0 0.14 10.8 0.0 1.3 1 0 0 1 1 1 0 ArgK protein AAA_17 PF13207.1 AIN99560.1 - 0.13 13.1 0.0 0.36 11.6 0.0 1.9 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.22 AIN99560.1 - 0.14 12.4 0.0 0.3 11.3 0.0 1.8 1 1 0 1 1 1 0 ABC transporter DSPc PF00782.15 AIN99561.1 - 5.8e-26 90.6 0.0 9.7e-26 89.9 0.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 AIN99561.1 - 0.00014 21.2 0.1 0.00047 19.5 0.0 1.7 2 0 0 2 2 2 1 Protein-tyrosine phosphatase Gelsolin PF00626.17 AIN99561.1 - 0.03 13.9 0.0 0.18 11.5 0.0 2.1 2 0 0 2 2 2 0 Gelsolin repeat PTPlike_phytase PF14566.1 AIN99561.1 - 0.2 11.7 0.0 0.41 10.6 0.0 1.5 1 0 0 1 1 1 0 Inositol hexakisphosphate Flagellar_rod PF05149.7 AIN99562.1 - 1.1e-107 359.5 21.7 2.7e-107 358.2 15.0 1.7 1 0 0 1 1 1 1 Paraflagellar rod protein SH3_9 PF14604.1 AIN99562.1 - 8.6e-12 44.4 0.0 1.7e-11 43.4 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 AIN99562.1 - 1.3e-11 43.6 0.0 2.4e-11 42.8 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 AIN99562.1 - 7.4e-09 34.9 0.0 1.4e-08 34.1 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain Mlp PF03304.8 AIN99562.1 - 0.0045 17.0 7.8 0.25 11.3 2.5 2.8 2 1 0 2 2 2 2 Mlp lipoprotein family ThiF PF00899.16 AIN99562.1 - 0.14 11.9 0.6 0.88 9.3 0.0 2.5 2 1 1 3 3 3 0 ThiF family GSP_synth PF03738.9 AIN99564.1 - 4.1e-25 87.8 0.1 8.8e-25 86.8 0.1 1.6 1 0 0 1 1 1 1 Glutathionylspermidine synthase preATP-grasp CHAP PF05257.11 AIN99564.1 - 8.9e-21 73.8 0.0 1.8e-20 72.8 0.0 1.5 1 0 0 1 1 1 1 CHAP domain YCII PF03795.9 AIN99565.1 - 0.086 13.0 0.1 0.2 11.8 0.1 1.6 1 0 0 1 1 1 0 YCII-related domain Mre11_DNA_bind PF04152.9 AIN99566.1 - 6e-31 107.6 0.0 2.7e-30 105.5 0.0 2.0 2 0 0 2 2 2 1 Mre11 DNA-binding presumed domain Metallophos PF00149.23 AIN99566.1 - 2e-18 66.4 0.1 1.4e-16 60.5 0.3 2.2 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase PSD5 PF07637.6 AIN99567.1 - 0.063 13.3 0.8 0.26 11.3 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1595) DUF846 PF05832.7 AIN99568.1 - 7.4e-44 148.8 11.9 9.4e-44 148.5 8.3 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF846) DUF4189 PF13827.1 AIN99569.1 - 0.42 10.9 6.2 0.41 10.9 3.0 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4189) TNFR_c6 PF00020.13 AIN99569.1 - 0.87 9.6 5.1 19 5.4 1.4 2.5 2 0 0 2 2 2 0 TNFR/NGFR cysteine-rich region Cmc1 PF08583.5 AIN99569.1 - 0.93 9.3 11.4 1.6 8.5 1.4 3.1 2 1 1 3 3 3 0 Cytochrome c oxidase biogenesis protein Cmc1 like DUF3611 PF12263.3 AIN99571.1 - 0.014 14.7 0.1 0.037 13.4 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3611) Amastin PF07344.6 AIN99571.1 - 0.037 13.6 0.1 0.082 12.5 0.0 1.6 1 1 0 1 1 1 0 Amastin surface glycoprotein 7TM_GPCR_Srv PF10323.4 AIN99571.1 - 0.15 11.1 5.3 0.14 11.2 2.2 1.8 2 0 0 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srv DUF4064 PF13273.1 AIN99571.1 - 5.4 7.1 7.5 26 4.9 2.9 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF4064) LRR19-TM PF15176.1 AIN99571.1 - 5.7 6.6 6.8 4.8 6.9 0.3 2.8 2 1 1 3 3 3 0 Leucine-rich repeat family 19 TM domain MGC-24 PF05283.6 AIN99572.1 - 0.049 13.4 4.4 0.087 12.6 3.1 1.4 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24) Pkinase PF00069.20 AIN99573.1 - 4.3e-45 153.9 0.0 6.9e-41 140.0 0.0 3.4 3 1 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.12 AIN99573.1 - 1.1e-22 80.4 0.0 2.2e-21 76.0 0.0 2.5 2 1 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 AIN99573.1 - 2.8e-07 29.8 0.6 5.1e-07 28.9 0.0 1.6 2 0 0 2 2 2 1 Kinase-like SDA1 PF05285.7 AIN99574.1 - 0.0011 18.3 10.0 0.0011 18.3 6.9 3.5 3 0 0 3 3 3 1 SDA1 Dpy-30 PF05186.8 AIN99574.1 - 0.0042 16.5 0.0 0.0086 15.5 0.0 1.5 1 0 0 1 1 1 1 Dpy-30 motif AAA_17 PF13207.1 AIN99574.1 - 0.0059 17.4 3.3 0.024 15.4 0.0 3.4 3 0 0 3 3 3 1 AAA domain Selenoprotein_S PF06936.6 AIN99574.1 - 2.1 7.8 8.8 1.2 8.6 4.4 1.8 2 0 0 2 2 2 0 Selenoprotein S (SelS) IFT43 PF15305.1 AIN99575.1 - 1.2e-07 31.8 2.2 3.2e-07 30.4 1.5 1.8 1 0 0 1 1 1 1 Intraflagellar transport protein 43 DUF3410 PF11890.3 AIN99575.1 - 0.11 12.1 0.3 11 5.7 0.1 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3410) LSM PF01423.17 AIN99576.1 - 4.4e-17 61.3 0.4 5.6e-17 61.0 0.3 1.1 1 0 0 1 1 1 1 LSM domain FtsJ PF01728.14 AIN99577.1 - 2.5e-56 190.5 0.1 4.2e-56 189.7 0.0 1.4 1 0 0 1 1 1 1 FtsJ-like methyltransferase Spb1_C PF07780.7 AIN99577.1 - 2.2e-33 115.5 16.4 2.2e-33 115.5 11.3 3.7 2 1 1 3 3 3 1 Spb1 C-terminal domain DUF3381 PF11861.3 AIN99577.1 - 9.3e-27 93.4 0.9 9.3e-27 93.4 0.6 4.8 6 1 0 6 6 6 1 Domain of unknown function (DUF3381) TrmB PF01978.14 AIN99577.1 - 0.068 12.8 0.3 0.25 11.0 0.2 2.0 1 1 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB RabGAP-TBC PF00566.13 AIN99578.1 - 2.6e-28 98.9 0.0 1e-15 57.8 0.0 3.3 3 0 0 3 3 3 3 Rab-GTPase-TBC domain TRAM1 PF08390.6 AIN99578.1 - 0.14 11.6 0.1 0.29 10.6 0.1 1.4 1 0 0 1 1 1 0 TRAM1-like protein GMP_PDE_delta PF05351.6 AIN99579.1 - 1.2e-62 210.3 0.0 1.4e-62 210.1 0.0 1.0 1 0 0 1 1 1 1 GMP-PDE, delta subunit DUF724 PF05266.9 AIN99580.1 - 0.041 13.5 0.8 0.075 12.6 0.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF724) FAD-oxidase_C PF02913.14 AIN99581.1 - 4.3e-40 137.6 0.3 1.1e-39 136.3 0.0 1.7 2 0 0 2 2 2 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.18 AIN99581.1 - 9.7e-37 125.5 2.0 3.1e-36 123.8 1.4 1.9 2 0 0 2 2 2 1 FAD binding domain Aminotran_4 PF01063.14 AIN99582.1 - 2.6e-25 89.2 0.0 3.5e-25 88.8 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class IV Glyco_trans_1_4 PF13692.1 AIN99582.1 - 0.1 12.7 0.1 0.76 9.9 0.0 2.2 2 0 0 2 2 2 0 Glycosyl transferases group 1 Erv26 PF04148.8 AIN99583.1 - 7e-18 64.7 15.1 6.7e-17 61.5 10.5 1.9 1 1 0 1 1 1 1 Transmembrane adaptor Erv26 Ribonuc_red_sm PF00268.16 AIN99584.1 - 1.9e-110 368.3 0.2 2.4e-110 368.0 0.2 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain DUF4064 PF13273.1 AIN99586.1 - 0.021 14.8 1.5 0.1 12.6 0.5 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF4064) RRM_1 PF00076.17 AIN99589.1 - 1.1e-32 111.4 0.0 1.7e-12 46.8 0.0 3.5 3 1 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 AIN99589.1 - 3.8e-30 103.6 0.0 3.9e-11 42.7 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 AIN99589.1 - 1.8e-09 37.2 0.1 2.4e-05 23.9 0.0 3.2 3 0 0 3 3 3 2 Nup53/35/40-type RNA recognition motif RRM_5 PF13893.1 AIN99589.1 - 2.1e-09 37.0 0.0 0.0018 18.1 0.0 3.6 3 1 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCHC PF00098.18 AIN99589.1 - 5.5e-05 22.8 0.6 0.00011 21.9 0.4 1.6 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_3 PF13917.1 AIN99589.1 - 0.038 13.7 2.1 0.086 12.5 1.4 1.5 1 0 0 1 1 1 0 Zinc knuckle RRM_3 PF08777.6 AIN99589.1 - 0.081 12.7 0.0 1.9 8.3 0.0 2.8 3 0 0 3 3 3 0 RNA binding motif Lipase_3 PF01764.20 AIN99590.1 - 7.4e-15 54.8 0.0 2.3e-13 49.9 0.0 2.4 1 1 0 1 1 1 1 Lipase (class 3) Abhydrolase_5 PF12695.2 AIN99590.1 - 0.0081 15.9 0.1 0.021 14.5 0.0 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF2974 PF11187.3 AIN99590.1 - 0.075 12.3 0.0 0.95 8.7 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2974) Motile_Sperm PF00635.21 AIN99591.1 - 1.1e-06 28.1 0.0 3.2e-06 26.7 0.0 1.7 1 1 0 1 1 1 1 MSP (Major sperm protein) domain PI3_PI4_kinase PF00454.22 AIN99593.1 - 6.4e-13 48.7 0.0 1.1e-12 47.8 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase DUF1465 PF07323.7 AIN99593.1 - 0.0082 15.7 1.2 0.02 14.4 0.2 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF1465) WD40 PF00400.27 AIN99596.1 - 7.4e-16 57.3 4.1 0.00048 19.9 0.3 7.4 8 0 0 8 8 8 3 WD domain, G-beta repeat IncA PF04156.9 AIN99596.1 - 0.0047 16.5 25.0 0.0047 16.5 17.3 4.9 2 1 2 4 4 4 2 IncA protein DUF2365 PF10157.4 AIN99596.1 - 0.083 12.7 0.1 0.083 12.7 0.1 4.3 3 1 0 4 4 4 0 Uncharacterized conserved protein (DUF2365) DUF2972 PF11186.3 AIN99596.1 - 0.15 11.9 7.7 0.021 14.7 2.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2972) Reo_sigmaC PF04582.7 AIN99596.1 - 0.68 9.0 11.9 0.56 9.3 0.8 3.1 1 1 1 3 3 3 0 Reovirus sigma C capsid protein NIF PF03031.13 AIN99597.1 - 9.4e-30 103.3 0.0 1.4e-29 102.7 0.0 1.3 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase VKOR PF07884.9 AIN99598.1 - 5.2e-13 49.0 17.7 2.5e-12 46.8 12.2 1.8 1 1 0 1 1 1 1 Vitamin K epoxide reductase family Thioredoxin PF00085.15 AIN99599.1 - 9.9e-07 28.4 0.0 2e-06 27.3 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin Phosducin PF02114.11 AIN99599.1 - 9.2e-05 21.2 0.1 0.0001 21.1 0.0 1.1 1 0 0 1 1 1 1 Phosducin Cwf_Cwc_15 PF04889.7 AIN99599.1 - 0.042 13.5 8.5 0.058 13.0 5.9 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein DSPc PF00782.15 AIN99600.1 - 2.7e-29 101.4 0.0 3.9e-29 100.9 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 AIN99600.1 - 0.00048 19.5 0.0 0.0007 19.0 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Ribosomal_L11_N PF03946.9 AIN99601.1 - 2.3e-14 52.5 0.0 4e-14 51.8 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.14 AIN99601.1 - 2.9e-10 40.1 0.0 5.7e-10 39.1 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain DUF1451 PF07295.6 AIN99602.1 - 2.2 8.0 6.1 0.35 10.6 0.5 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1451) Atg14 PF10186.4 AIN99603.1 - 4.2e-05 22.6 14.7 0.00013 21.0 10.2 1.8 1 1 0 1 1 1 1 UV radiation resistance protein and autophagy-related subunit 14 DUF4045 PF13254.1 AIN99603.1 - 0.032 13.5 3.6 0.046 13.0 2.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) DUF3573 PF12097.3 AIN99603.1 - 0.54 8.8 1.3 0.79 8.2 0.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) APG6 PF04111.7 AIN99603.1 - 2.1 7.3 9.8 69 2.3 0.0 2.3 2 0 0 2 2 2 0 Autophagy protein Apg6 EMG1 PF03587.9 AIN99604.1 - 3.8e-40 137.3 0.0 4.5e-40 137.1 0.0 1.1 1 0 0 1 1 1 1 EMG1/NEP1 methyltransferase Mcp5_PH PF12814.2 AIN99607.1 - 1.2e-15 57.5 0.3 1.4e-15 57.3 0.2 1.1 1 0 0 1 1 1 1 Meiotic cell cortex C-terminal pleckstrin homology PH PF00169.24 AIN99607.1 - 0.00018 21.6 0.3 0.00025 21.2 0.2 1.2 1 0 0 1 1 1 1 PH domain PH_2 PF08458.5 AIN99607.1 - 0.031 14.2 0.0 0.045 13.6 0.0 1.3 1 0 0 1 1 1 0 Plant pleckstrin homology-like region ACOX PF01756.14 AIN99608.1 - 2e-05 24.0 0.0 4.7e-05 22.8 0.0 1.6 2 0 0 2 2 2 1 Acyl-CoA oxidase Cupin_1 PF00190.17 AIN99608.1 - 0.067 12.6 0.0 0.13 11.6 0.0 1.4 1 0 0 1 1 1 0 Cupin Spt5-NGN PF03439.8 AIN99609.1 - 7.5e-21 73.6 1.0 3e-20 71.7 0.1 2.5 3 0 0 3 3 3 1 Early transcription elongation factor of RNA pol II, NGN section Spt5_N PF11942.3 AIN99609.1 - 2e-08 34.7 13.5 2e-08 34.7 9.4 2.9 2 1 1 3 3 3 1 Spt5 transcription elongation factor, acidic N-terminal KOW PF00467.24 AIN99609.1 - 3.2e-07 29.8 3.3 0.026 14.2 0.0 4.3 4 1 0 4 4 4 2 KOW motif HAS-barrel PF09378.5 AIN99609.1 - 0.0035 17.2 3.2 0.59 10.0 0.0 3.6 4 0 0 4 4 4 2 HAS barrel domain MORN PF02493.15 AIN99610.1 - 9.4e-20 69.1 15.8 4e-06 26.2 0.0 4.6 5 0 0 5 5 5 4 MORN repeat PP2C PF00481.16 AIN99612.1 - 1.3e-74 250.8 0.0 1.6e-74 250.5 0.0 1.0 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.1 AIN99612.1 - 0.017 14.4 0.3 0.11 11.8 0.2 2.3 1 1 0 1 1 1 0 Protein phosphatase 2C SCRL PF06876.7 AIN99612.1 - 0.052 13.5 0.1 0.15 12.0 0.0 1.7 1 0 0 1 1 1 0 Plant self-incompatibility response (SCRL) protein YchF-GTPase_C PF06071.8 AIN99613.1 - 1.4e-36 124.1 0.5 3.3e-36 122.9 0.3 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF933) MMR_HSR1 PF01926.18 AIN99613.1 - 6.2e-17 61.6 0.0 1.2e-16 60.7 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 AIN99613.1 - 0.00023 20.4 0.0 0.0006 19.1 0.0 1.7 2 0 0 2 2 2 1 Ferrous iron transport protein B AAA_17 PF13207.1 AIN99613.1 - 0.0026 18.5 0.2 0.017 15.8 0.1 2.6 1 1 0 1 1 1 1 AAA domain TGS PF02824.16 AIN99613.1 - 0.0043 16.8 0.0 0.01 15.6 0.0 1.6 1 0 0 1 1 1 1 TGS domain ArgK PF03308.11 AIN99613.1 - 0.025 13.3 0.0 0.041 12.6 0.0 1.3 1 0 0 1 1 1 0 ArgK protein AAA_18 PF13238.1 AIN99613.1 - 0.069 13.4 0.0 0.22 11.8 0.0 1.9 2 0 0 2 2 2 0 AAA domain Dynamin_N PF00350.18 AIN99613.1 - 0.088 12.6 0.1 14 5.4 0.1 2.5 1 1 1 2 2 2 0 Dynamin family Cpn60_TCP1 PF00118.19 AIN99615.1 - 0.12 10.9 0.0 0.18 10.3 0.0 1.2 1 0 0 1 1 1 0 TCP-1/cpn60 chaperonin family Glyco_hydro_32N PF00251.15 AIN99616.1 - 4.8e-85 285.6 1.3 5.9e-85 285.3 0.9 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 N-terminal domain Glyco_hydro_32C PF08244.7 AIN99616.1 - 1.7e-05 25.1 0.0 3.3e-05 24.1 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 C terminal Glyco_hydro_43 PF04616.9 AIN99616.1 - 0.00026 20.1 0.2 0.0004 19.5 0.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 BNR_2 PF13088.1 AIN99616.1 - 0.015 14.5 0.1 0.084 12.1 0.1 1.8 1 1 0 1 1 1 0 BNR repeat-like domain TPR_11 PF13414.1 AIN99618.1 - 3.5e-19 68.2 4.0 3.3e-13 49.0 0.1 3.1 2 1 1 3 3 3 2 TPR repeat RPAP3_C PF13877.1 AIN99618.1 - 4.6e-18 64.9 0.0 8.1e-18 64.1 0.0 1.4 1 0 0 1 1 1 1 Potential Monad-binding region of RPAP3 TPR_2 PF07719.12 AIN99618.1 - 1.7e-13 49.3 2.6 7.5e-05 22.3 0.5 4.2 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.23 AIN99618.1 - 7.9e-12 44.2 2.3 5.5e-05 22.5 0.2 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.1 AIN99618.1 - 8e-08 31.5 0.5 0.018 14.7 0.0 4.0 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_9 PF13371.1 AIN99618.1 - 2.9e-07 30.2 2.5 1e-06 28.4 0.8 5.2 3 1 2 5 5 4 3 Tetratricopeptide repeat TPR_17 PF13431.1 AIN99618.1 - 4.7e-05 23.2 0.1 0.7 10.2 0.0 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.1 AIN99618.1 - 0.0018 18.2 5.4 0.0069 16.3 2.2 2.9 1 1 1 2 2 2 1 Tetratricopeptide repeat Apc3 PF12895.2 AIN99618.1 - 0.007 16.4 2.7 0.044 13.9 1.9 2.2 1 1 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.1 AIN99618.1 - 0.015 15.8 2.0 0.015 15.8 1.4 5.6 5 2 1 6 6 4 0 Tetratricopeptide repeat TPR_19 PF14559.1 AIN99618.1 - 0.032 14.5 5.4 0.33 11.3 0.1 3.4 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.1 AIN99618.1 - 0.14 12.0 7.7 10 6.2 0.0 4.7 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_6 PF13174.1 AIN99618.1 - 0.43 11.1 16.5 0.13 12.7 0.5 4.3 5 0 0 5 5 2 0 Tetratricopeptide repeat TPR_16 PF13432.1 AIN99618.1 - 0.47 11.1 23.0 0.51 11.0 4.0 5.1 4 2 0 4 4 4 0 Tetratricopeptide repeat Ndc1_Nup PF09531.5 AIN99618.1 - 0.56 8.5 4.2 0.88 7.9 2.9 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup SOBP PF15279.1 AIN99618.1 - 1.4 9.2 11.8 2.8 8.2 8.2 1.4 1 0 0 1 1 1 0 Sine oculis-binding protein Synaptobrevin PF00957.16 AIN99619.1 - 9.3e-25 86.0 0.7 1.4e-24 85.4 0.5 1.3 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.1 AIN99619.1 - 4.3e-12 45.4 0.1 6.9e-12 44.7 0.1 1.5 1 0 0 1 1 1 1 Regulated-SNARE-like domain MSC PF09402.5 AIN99619.1 - 0.022 13.4 0.1 0.024 13.3 0.1 1.2 1 0 0 1 1 1 0 Man1-Src1p-C-terminal domain Adeno_E3_CR2 PF02439.10 AIN99619.1 - 6.6 6.3 7.5 13 5.4 5.2 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 DUF1345 PF07077.6 AIN99621.1 - 0.075 12.5 0.1 0.1 12.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1345) DnaJ PF00226.26 AIN99622.1 - 1.9e-27 94.7 0.5 3.7e-27 93.8 0.3 1.5 1 0 0 1 1 1 1 DnaJ domain CTDII PF01556.13 AIN99622.1 - 1.6e-19 69.6 0.1 9e-16 57.5 0.0 3.4 3 0 0 3 3 3 2 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.14 AIN99622.1 - 7.4e-14 51.5 15.8 1.2e-13 50.8 10.9 1.3 1 0 0 1 1 1 1 DnaJ central domain HypA PF01155.14 AIN99622.1 - 0.047 13.3 7.1 2.1 8.0 0.3 2.6 2 0 0 2 2 2 0 Hydrogenase expression/synthesis hypA family DZR PF12773.2 AIN99622.1 - 0.15 11.8 9.7 0.58 10.0 1.1 2.5 2 0 0 2 2 2 0 Double zinc ribbon Antiterm PF03589.8 AIN99622.1 - 1.8 8.6 9.1 12 6.0 1.2 3.4 1 1 1 2 2 2 0 Antitermination protein Aldo_ket_red PF00248.16 AIN99623.1 - 9e-42 142.8 0.0 1.1e-41 142.4 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family TBPIP PF07106.8 AIN99624.1 - 2.4e-07 30.4 0.0 4.1e-07 29.6 0.0 1.3 1 0 0 1 1 1 1 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) UxaC PF02614.9 AIN99624.1 - 0.0063 15.1 0.0 0.0093 14.6 0.0 1.2 1 0 0 1 1 1 1 Glucuronate isomerase Cep57_MT_bd PF06657.8 AIN99624.1 - 0.012 15.5 0.0 0.031 14.2 0.0 1.7 1 0 0 1 1 1 0 Centrosome microtubule-binding domain of Cep57 adh_short PF00106.20 AIN99626.1 - 2.4e-24 86.1 3.3 3.5e-24 85.5 2.3 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 AIN99626.1 - 3.4e-20 72.8 0.0 3.9e-20 72.6 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 AIN99626.1 - 7.1e-13 48.6 2.6 3.3e-12 46.4 1.8 1.8 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 AIN99626.1 - 7.7e-06 25.5 0.0 1.9e-05 24.2 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 AIN99626.1 - 0.0092 14.9 0.0 1.5 7.6 0.0 2.2 2 0 0 2 2 2 2 Male sterility protein Pkinase PF00069.20 AIN99628.1 - 5.1e-54 183.1 0.0 6.4e-54 182.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AIN99628.1 - 9.8e-25 87.0 0.0 1.5e-24 86.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 AIN99628.1 - 3.4e-05 22.9 0.0 0.0097 14.8 0.0 2.4 3 0 0 3 3 3 2 Kinase-like APH PF01636.18 AIN99628.1 - 0.0066 16.2 0.7 0.25 11.0 0.2 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.9 AIN99628.1 - 0.038 13.0 0.0 0.057 12.4 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.20 AIN99629.1 - 2.6e-65 220.1 0.0 4.3e-65 219.4 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AIN99629.1 - 5.5e-30 104.2 0.0 8.1e-30 103.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 AIN99629.1 - 0.00021 20.3 0.0 0.0082 15.1 0.0 2.7 2 1 0 2 2 2 1 Kinase-like Kdo PF06293.9 AIN99629.1 - 0.052 12.5 0.2 0.53 9.3 0.0 2.2 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Prp19 PF08606.6 AIN99630.1 - 1.7e-26 91.7 0.5 3.4e-26 90.7 0.3 1.5 1 0 0 1 1 1 1 Prp19/Pso4-like WD40 PF00400.27 AIN99630.1 - 0.00024 20.8 13.8 0.037 13.9 0.0 5.2 6 0 0 6 6 6 3 WD domain, G-beta repeat DUF3312 PF11768.3 AIN99630.1 - 0.0021 16.3 0.1 0.65 8.1 0.0 2.2 1 1 1 2 2 2 2 Protein of unknown function (DUF3312) U-box PF04564.10 AIN99630.1 - 0.018 14.9 0.0 0.04 13.8 0.0 1.5 1 0 0 1 1 1 0 U-box domain zf-Nse PF11789.3 AIN99630.1 - 0.027 13.9 0.1 0.052 13.0 0.1 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit TTL PF03133.10 AIN99631.1 - 1.3e-48 165.4 0.0 1.8e-48 164.9 0.0 1.1 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family ATP-grasp_4 PF13535.1 AIN99631.1 - 0.0008 19.1 0.0 0.042 13.5 0.0 2.8 3 0 0 3 3 3 1 ATP-grasp domain ATPgrasp_YheCD PF14398.1 AIN99631.1 - 0.016 13.9 0.0 24 3.5 0.0 3.1 2 1 1 3 3 3 0 YheC/D like ATP-grasp Dala_Dala_lig_C PF07478.8 AIN99631.1 - 0.025 13.9 0.0 0.04 13.3 0.0 1.2 1 0 0 1 1 1 0 D-ala D-ala ligase C-terminus ATPgrasp_Ter PF15632.1 AIN99631.1 - 0.028 13.1 0.0 0.95 8.1 0.0 2.1 2 0 0 2 2 2 0 ATP-grasp in the biosynthetic pathway with Ter operon PSII_Pbs27 PF13326.1 AIN99632.1 - 0.024 14.5 0.9 0.04 13.9 0.4 1.6 2 0 0 2 2 2 0 Photosystem II Pbs27 SICA_alpha PF12887.2 AIN99632.1 - 0.031 14.0 0.4 0.043 13.5 0.3 1.2 1 0 0 1 1 1 0 SICA extracellular alpha domain DUF2884 PF11101.3 AIN99632.1 - 0.042 13.2 0.5 0.06 12.7 0.3 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2884) Kri1 PF05178.7 AIN99632.1 - 1.7 8.9 7.7 0.13 12.5 2.2 1.4 2 0 0 2 2 2 0 KRI1-like family HTH_12 PF08461.5 AIN99632.1 - 5.4 6.8 7.6 6.3 6.5 1.4 2.6 2 1 1 3 3 3 0 Ribonuclease R winged-helix domain Dynein_heavy PF03028.10 AIN99633.1 - 2.1e-214 713.6 0.0 3.5e-214 712.9 0.0 1.4 1 0 0 1 1 1 1 Dynein heavy chain and region D6 of dynein motor DHC_N2 PF08393.8 AIN99633.1 - 4.4e-114 381.1 3.2 4.4e-114 381.1 2.2 1.9 2 0 0 2 2 2 1 Dynein heavy chain, N-terminal region 2 AAA_6 PF12774.2 AIN99633.1 - 7.3e-96 320.1 0.1 5e-95 317.4 0.0 2.5 2 0 0 2 2 2 1 Hydrolytic ATP binding site of dynein motor region D1 AAA_8 PF12780.2 AIN99633.1 - 2.8e-62 210.1 0.0 5.6e-62 209.1 0.0 1.5 1 0 0 1 1 1 1 P-loop containing dynein motor region D4 AAA_9 PF12781.2 AIN99633.1 - 3.3e-52 176.6 0.7 6.8e-52 175.5 0.5 1.5 1 0 0 1 1 1 1 ATP-binding dynein motor region D5 AAA_7 PF12775.2 AIN99633.1 - 4.9e-52 176.6 0.0 8.5e-52 175.8 0.0 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region D3 MT PF12777.2 AIN99633.1 - 2e-27 95.8 8.7 2e-27 95.8 6.0 2.0 2 0 0 2 2 2 1 Microtubule-binding stalk of dynein motor AAA_5 PF07728.9 AIN99633.1 - 3e-19 69.1 0.0 5.3e-05 22.9 0.0 6.0 5 2 1 6 6 6 3 AAA domain (dynein-related subfamily) AAA PF00004.24 AIN99633.1 - 4.9e-09 36.4 2.7 0.0026 17.9 0.0 4.1 4 0 0 4 4 4 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 AIN99633.1 - 5.3e-07 29.8 1.7 0.15 12.1 0.0 5.9 5 0 0 5 5 5 2 AAA domain AAA_16 PF13191.1 AIN99633.1 - 8.9e-06 25.8 8.9 0.011 15.7 0.0 5.9 4 0 0 4 4 4 1 AAA ATPase domain AAA_18 PF13238.1 AIN99633.1 - 0.00012 22.3 0.0 0.1 12.8 0.0 3.7 3 0 0 3 3 2 1 AAA domain AAA_17 PF13207.1 AIN99633.1 - 0.00023 21.9 0.0 0.0087 16.8 0.0 3.6 2 0 0 2 2 2 1 AAA domain T2SE PF00437.15 AIN99633.1 - 0.00056 18.8 0.4 0.0058 15.5 0.0 2.9 3 0 0 3 3 3 1 Type II/IV secretion system protein RNA_helicase PF00910.17 AIN99633.1 - 0.0028 17.8 0.1 2.6 8.2 0.0 3.2 2 0 0 2 2 2 1 RNA helicase UPF0079 PF02367.12 AIN99633.1 - 0.022 14.3 1.1 4.4 6.9 0.0 3.1 3 0 0 3 3 3 0 Uncharacterised P-loop hydrolase UPF0079 MobB PF03205.9 AIN99633.1 - 0.09 12.4 0.1 0.56 9.9 0.0 2.3 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B Macoilin PF09726.4 AIN99635.1 - 0.013 13.8 0.7 0.015 13.6 0.5 1.2 1 0 0 1 1 1 0 Transmembrane protein T2SJ PF11612.3 AIN99635.1 - 0.022 14.5 6.8 0.82 9.3 0.1 2.5 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein J IncA PF04156.9 AIN99635.1 - 0.032 13.8 5.4 0.34 10.4 4.0 2.1 2 0 0 2 2 2 0 IncA protein Cluap1 PF10234.4 AIN99635.1 - 1.4 8.0 7.0 0.35 10.0 1.9 1.9 2 0 0 2 2 2 0 Clusterin-associated protein-1 Mnd1 PF03962.10 AIN99635.1 - 8 6.0 9.5 0.47 10.0 2.6 1.8 2 1 0 2 2 2 0 Mnd1 family Reo_sigmaC PF04582.7 AIN99636.1 - 6.8 5.7 27.6 0.66 9.0 2.6 4.7 1 1 4 6 6 6 0 Reovirus sigma C capsid protein AAA_2 PF07724.9 AIN99637.1 - 1.6e-52 177.8 0.0 6e-50 169.5 0.0 2.6 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA PF00004.24 AIN99637.1 - 9.6e-24 84.0 0.1 5.7e-14 52.4 0.0 3.2 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.4 AIN99637.1 - 1.5e-21 76.0 0.2 4.9e-21 74.4 0.1 2.0 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA_5 PF07728.9 AIN99637.1 - 2.6e-18 66.0 0.2 2.7e-10 40.1 0.0 4.2 4 0 0 4 4 4 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 AIN99637.1 - 3.2e-13 50.0 1.1 0.00029 20.8 0.0 4.5 3 2 1 4 4 4 3 AAA ATPase domain AAA_22 PF13401.1 AIN99637.1 - 2.3e-10 40.7 2.4 0.00013 22.0 0.0 4.7 4 2 0 4 4 4 2 AAA domain AAA_17 PF13207.1 AIN99637.1 - 3e-07 31.2 0.6 0.007 17.1 0.0 3.4 2 1 0 2 2 2 2 AAA domain AAA_18 PF13238.1 AIN99637.1 - 3.6e-06 27.3 1.6 0.077 13.2 0.0 3.2 3 0 0 3 3 3 2 AAA domain IstB_IS21 PF01695.12 AIN99637.1 - 1.8e-05 24.2 0.0 0.029 13.7 0.0 2.8 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_14 PF13173.1 AIN99637.1 - 3.9e-05 23.5 0.0 0.34 10.8 0.0 3.1 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.17 AIN99637.1 - 4.8e-05 23.4 0.0 0.7 10.0 0.0 3.0 3 0 0 3 3 2 2 RNA helicase Mg_chelatase PF01078.16 AIN99637.1 - 4.9e-05 22.5 0.0 0.31 10.1 0.0 3.3 3 0 0 3 3 3 2 Magnesium chelatase, subunit ChlI Arch_ATPase PF01637.13 AIN99637.1 - 0.00014 21.6 2.0 1.4 8.5 0.0 4.6 3 1 2 5 5 5 1 Archaeal ATPase DNA_pol3_delta2 PF13177.1 AIN99637.1 - 0.00015 21.4 0.2 0.04 13.5 0.0 3.9 3 2 0 3 3 3 1 DNA polymerase III, delta subunit AAA_25 PF13481.1 AIN99637.1 - 0.00038 19.9 0.0 2.2 7.6 0.0 3.5 2 2 1 3 3 3 2 AAA domain NACHT PF05729.7 AIN99637.1 - 0.00041 20.0 0.0 0.041 13.5 0.0 3.4 3 0 0 3 3 3 1 NACHT domain RuvB_N PF05496.7 AIN99637.1 - 0.00057 19.0 0.2 1.1 8.2 0.0 3.2 3 0 0 3 3 3 1 Holliday junction DNA helicase ruvB N-terminus Sigma54_activat PF00158.21 AIN99637.1 - 0.00063 19.2 0.0 0.32 10.4 0.0 2.8 2 1 0 2 2 2 1 Sigma-54 interaction domain AAA_3 PF07726.6 AIN99637.1 - 0.00067 19.2 0.0 1.1 8.8 0.0 3.3 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.1 AIN99637.1 - 0.00089 18.9 0.0 0.098 12.4 0.0 2.8 2 0 0 2 2 2 1 Part of AAA domain MobB PF03205.9 AIN99637.1 - 0.0011 18.7 0.0 0.31 10.7 0.0 2.7 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B Ribosomal_S7 PF00177.16 AIN99637.1 - 0.0021 17.6 0.1 0.0088 15.6 0.0 2.0 2 0 0 2 2 1 1 Ribosomal protein S7p/S5e ResIII PF04851.10 AIN99637.1 - 0.0037 17.1 1.6 1.1 9.0 0.0 3.7 3 1 1 4 4 4 1 Type III restriction enzyme, res subunit AAA_28 PF13521.1 AIN99637.1 - 0.0038 17.2 0.0 1.3 8.9 0.0 3.1 3 0 0 3 3 2 1 AAA domain DUF815 PF05673.8 AIN99637.1 - 0.0059 15.5 0.1 0.16 10.8 0.0 3.1 3 1 0 3 3 3 1 Protein of unknown function (DUF815) SRP54 PF00448.17 AIN99637.1 - 0.007 15.8 0.0 1.1 8.7 0.0 3.1 3 0 0 3 3 3 1 SRP54-type protein, GTPase domain Zeta_toxin PF06414.7 AIN99637.1 - 0.0079 15.3 0.0 1.2 8.2 0.0 2.9 2 1 0 2 2 2 1 Zeta toxin AAA_24 PF13479.1 AIN99637.1 - 0.01 15.4 0.0 1 8.9 0.0 2.5 2 0 0 2 2 2 0 AAA domain Torsin PF06309.6 AIN99637.1 - 0.012 15.4 0.0 0.043 13.7 0.0 1.9 2 0 0 2 2 1 0 Torsin DUF258 PF03193.11 AIN99637.1 - 0.013 14.6 0.0 2.3 7.3 0.0 2.8 2 0 0 2 2 2 0 Protein of unknown function, DUF258 NTPase_1 PF03266.10 AIN99637.1 - 0.021 14.5 0.0 3.7 7.2 0.0 3.0 3 0 0 3 3 2 0 NTPase AAA_29 PF13555.1 AIN99637.1 - 0.031 13.8 0.0 4.9 6.7 0.0 2.6 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_33 PF13671.1 AIN99637.1 - 0.034 14.0 0.0 8.3 6.2 0.0 2.7 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.22 AIN99637.1 - 0.041 14.1 1.7 8.3 6.7 0.0 3.3 3 1 0 3 3 3 0 ABC transporter Miro PF08477.8 AIN99637.1 - 0.042 14.3 0.1 0.38 11.2 0.0 2.6 3 0 0 3 3 2 0 Miro-like protein UPF0079 PF02367.12 AIN99637.1 - 0.044 13.4 0.0 13 5.4 0.0 2.9 3 0 0 3 3 2 0 Uncharacterised P-loop hydrolase UPF0079 MMR_HSR1 PF01926.18 AIN99637.1 - 0.076 12.9 0.1 2.2 8.2 0.0 3.0 3 0 0 3 3 2 0 50S ribosome-binding GTPase ATP_bind_1 PF03029.12 AIN99637.1 - 0.086 12.3 0.0 3 7.3 0.0 2.5 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_10 PF12846.2 AIN99637.1 - 0.13 11.6 1.3 16 4.8 0.0 3.8 3 2 1 4 4 4 0 AAA-like domain V_ATPase_I PF01496.14 AIN99637.1 - 0.22 9.3 7.1 0.31 8.8 4.9 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Peptidase_M3 PF01432.15 AIN99638.1 - 9.8e-97 324.8 0.0 1.1e-96 324.7 0.0 1.0 1 0 0 1 1 1 1 Peptidase family M3 Peptidase_M50B PF13398.1 AIN99638.1 - 0.017 14.5 0.0 0.028 13.7 0.0 1.3 1 0 0 1 1 1 0 Peptidase M50B-like Methyltransf_26 PF13659.1 AIN99639.1 - 0.0014 18.6 0.1 0.0036 17.3 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 AIN99639.1 - 0.003 18.1 0.0 0.0069 16.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 AIN99639.1 - 0.014 15.6 0.0 0.032 14.5 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Topo_C_assoc PF14370.1 AIN99640.1 - 0.073 12.7 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 C-terminal topoisomerase domain AAA PF00004.24 AIN99641.1 - 1.6e-09 38.0 0.0 1.2e-08 35.2 0.0 2.3 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 AIN99641.1 - 8.1e-07 29.2 0.0 6.6e-06 26.2 0.0 2.3 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.1 AIN99641.1 - 3.2e-05 23.9 0.0 0.00011 22.2 0.0 1.9 1 0 0 1 1 1 1 AAA ATPase domain Arch_ATPase PF01637.13 AIN99641.1 - 0.00081 19.1 0.0 0.0096 15.6 0.0 2.1 1 1 0 1 1 1 1 Archaeal ATPase T2SE PF00437.15 AIN99641.1 - 0.0039 16.1 0.0 0.012 14.5 0.0 1.7 2 0 0 2 2 2 1 Type II/IV secretion system protein FtsK_SpoIIIE PF01580.13 AIN99641.1 - 0.0043 16.5 0.0 0.016 14.6 0.0 1.9 1 1 0 1 1 1 1 FtsK/SpoIIIE family AAA_11 PF13086.1 AIN99641.1 - 0.0069 15.9 0.0 0.014 15.0 0.0 1.5 1 1 0 1 1 1 1 AAA domain NACHT PF05729.7 AIN99641.1 - 0.011 15.4 0.0 0.022 14.3 0.0 1.6 1 0 0 1 1 1 0 NACHT domain NB-ARC PF00931.17 AIN99641.1 - 0.021 13.7 0.0 0.033 13.0 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain DUF2075 PF09848.4 AIN99641.1 - 0.033 13.1 0.0 0.06 12.3 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_19 PF13245.1 AIN99641.1 - 0.044 13.5 0.0 0.1 12.4 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain AAA_33 PF13671.1 AIN99641.1 - 0.077 12.8 1.4 0.96 9.3 0.1 2.6 2 1 0 2 2 2 0 AAA domain PPR PF01535.15 AIN99642.1 - 2.6e-06 27.0 0.1 2.5 8.2 0.0 6.0 6 0 0 6 6 6 2 PPR repeat PPR_2 PF13041.1 AIN99642.1 - 0.0004 20.2 0.1 1.2 9.1 0.0 5.0 5 1 1 6 6 6 2 PPR repeat family NYD-SP28_assoc PF14775.1 AIN99643.1 - 2.2e-05 24.0 1.3 0.00012 21.6 0.9 2.4 1 0 0 1 1 1 1 Sperm tail C-terminal domain NYD-SP28 PF14772.1 AIN99643.1 - 4.5e-05 23.4 4.9 4.5e-05 23.4 3.4 4.4 2 1 3 5 5 5 1 Sperm tail Ank_2 PF12796.2 AIN99646.1 - 7.4e-07 29.4 0.5 0.00023 21.4 0.1 2.9 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.1 AIN99646.1 - 0.0017 18.3 4.0 3.3 8.2 0.0 5.6 6 0 0 6 6 6 1 Ankyrin repeat Ank_4 PF13637.1 AIN99646.1 - 0.0018 18.7 0.3 0.014 15.9 0.0 2.8 2 1 1 3 3 3 1 Ankyrin repeats (many copies) Ank PF00023.25 AIN99646.1 - 0.0097 15.6 1.4 1.2 9.1 0.0 3.9 3 1 0 3 3 3 1 Ankyrin repeat IQ PF00612.22 AIN99646.1 - 0.01 15.4 10.8 1.6 8.5 0.0 4.8 4 0 0 4 4 4 2 IQ calmodulin-binding motif Ank_5 PF13857.1 AIN99646.1 - 0.017 15.3 1.4 0.26 11.5 0.1 3.2 3 0 0 3 3 3 0 Ankyrin repeats (many copies) Proteasome PF00227.21 AIN99648.1 - 1e-39 135.8 0.0 1.1e-39 135.6 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit TFIIS_C PF01096.13 AIN99649.1 - 0.0001 21.8 2.4 0.0001 21.8 1.6 3.1 3 1 0 3 3 3 1 Transcription factor S-II (TFIIS) Ogr_Delta PF04606.7 AIN99649.1 - 0.00072 19.1 1.1 0.00072 19.1 0.7 2.5 2 2 0 2 2 1 1 Ogr/Delta-like zinc finger zf-Sec23_Sec24 PF04810.10 AIN99649.1 - 0.0013 18.2 3.4 0.0013 18.2 2.4 1.8 2 0 0 2 2 2 1 Sec23/Sec24 zinc finger RNA_POL_M_15KD PF02150.11 AIN99649.1 - 0.0034 17.0 5.8 0.0034 17.0 4.0 2.5 2 0 0 2 2 2 1 RNA polymerases M/15 Kd subunit Zn_Tnp_IS1595 PF12760.2 AIN99649.1 - 0.033 13.9 0.9 0.033 13.9 0.7 2.5 2 1 0 2 2 2 0 Transposase zinc-ribbon domain zf-ribbon_3 PF13248.1 AIN99649.1 - 0.15 11.2 8.1 1.8 7.9 0.5 3.3 3 0 0 3 3 3 0 zinc-ribbon domain Zn_ribbon_recom PF13408.1 AIN99649.1 - 0.79 10.0 8.1 0.4 10.9 1.5 2.2 2 0 0 2 2 2 0 Recombinase zinc beta ribbon domain HypA PF01155.14 AIN99649.1 - 3.6 7.3 6.4 23 4.7 4.5 2.1 1 1 0 1 1 1 0 Hydrogenase expression/synthesis hypA family zf-RING_3 PF14369.1 AIN99649.1 - 3.8 7.5 10.5 9.9 6.2 0.3 2.8 2 0 0 2 2 2 0 zinc-finger DUF2296 PF10058.4 AIN99649.1 - 4.2 7.1 7.4 0.92 9.3 1.3 2.4 2 0 0 2 2 2 0 Predicted integral membrane metal-binding protein (DUF2296) Lar_restr_allev PF14354.1 AIN99649.1 - 6.3 7.1 15.1 0.16 12.2 1.6 2.5 2 1 0 2 2 2 0 Restriction alleviation protein Lar Col_cuticle_N PF01484.12 AIN99650.1 - 0.028 14.1 0.6 0.059 13.0 0.4 1.6 1 0 0 1 1 1 0 Nematode cuticle collagen N-terminal domain DUF3311 PF11755.3 AIN99650.1 - 0.42 10.1 3.9 1.4 8.4 0.8 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3311) ABC2_membrane_4 PF12730.2 AIN99650.1 - 2 7.5 11.6 9.6 5.2 8.3 1.7 1 1 0 1 1 1 0 ABC-2 family transporter protein Fumble PF03630.9 AIN99651.1 - 1.7e-73 247.4 0.0 2.9e-73 246.6 0.0 1.3 1 0 0 1 1 1 1 Fumble Exo_endo_phos PF03372.18 AIN99651.1 - 6.2e-15 55.8 0.0 1.1e-14 55.0 0.0 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family AMP-binding PF00501.23 AIN99651.1 - 1e-12 47.1 0.7 1.5e-08 33.4 0.0 2.2 2 0 0 2 2 2 2 AMP-binding enzyme Spo7_2_N PF15407.1 AIN99652.1 - 0.027 13.9 0.0 0.094 12.1 0.0 1.8 2 0 0 2 2 2 0 Sporulation protein family 7 RRM_6 PF14259.1 AIN99652.1 - 0.052 13.5 0.0 0.25 11.3 0.0 2.0 1 1 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 AIN99652.1 - 0.12 11.9 0.0 0.92 9.1 0.0 2.1 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DSPc PF00782.15 AIN99653.1 - 9.6e-26 89.9 0.0 1.8e-25 89.0 0.0 1.5 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain LRR_8 PF13855.1 AIN99653.1 - 4.1e-06 26.4 12.7 0.0049 16.5 1.8 4.2 3 1 0 3 3 3 2 Leucine rich repeat LRR_4 PF12799.2 AIN99653.1 - 5.7e-06 25.8 12.4 7.7e-05 22.2 3.4 3.9 2 1 3 5 5 5 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 AIN99653.1 - 4.9e-05 22.8 9.2 0.88 9.8 0.0 5.1 5 0 0 5 5 5 3 Leucine Rich Repeat Y_phosphatase PF00102.22 AIN99653.1 - 0.00093 18.5 0.0 0.0015 17.8 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase LRR_7 PF13504.1 AIN99653.1 - 0.0017 18.2 13.4 0.046 13.9 0.2 5.3 7 0 0 7 7 7 2 Leucine rich repeat CDKN3 PF05706.7 AIN99653.1 - 0.11 11.9 0.0 0.2 11.0 0.0 1.4 1 0 0 1 1 1 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) Y_phosphatase3 PF13350.1 AIN99653.1 - 0.11 12.7 0.0 0.28 11.4 0.0 1.6 2 0 0 2 2 2 0 Tyrosine phosphatase family Histone PF00125.19 AIN99657.1 - 1.3e-14 54.0 0.8 1.8e-14 53.5 0.5 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Cylicin_N PF15241.1 AIN99657.1 - 0.013 15.4 0.2 0.018 14.9 0.2 1.3 1 0 0 1 1 1 0 Cylicin N-terminus CBFD_NFYB_HMF PF00808.18 AIN99657.1 - 0.021 14.8 0.3 0.021 14.8 0.2 1.7 2 0 0 2 2 2 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone zf-DHHC PF01529.15 AIN99658.1 - 7.5e-32 110.1 0.8 7.5e-32 110.1 0.5 1.6 2 0 0 2 2 2 1 DHHC palmitoyltransferase Viral_NABP PF05515.6 AIN99658.1 - 0.7 10.1 3.9 1.5 9.1 2.7 1.5 1 0 0 1 1 1 0 Viral nucleic acid binding AzlD PF05437.7 AIN99658.1 - 0.87 9.5 7.1 5 7.1 1.0 3.2 2 1 0 2 2 2 0 Branched-chain amino acid transport protein (AzlD) DAO PF01266.19 AIN99660.1 - 2.4e-39 135.2 0.0 4.8e-39 134.2 0.0 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_oxidored PF12831.2 AIN99660.1 - 0.0034 16.5 1.1 0.0057 15.7 0.7 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 AIN99660.1 - 0.0094 14.8 1.3 0.018 13.8 0.9 1.5 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 AIN99660.1 - 0.013 15.3 1.7 0.054 13.3 0.1 2.7 3 1 1 4 4 4 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 AIN99660.1 - 0.046 13.7 1.3 0.15 12.1 0.9 1.9 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain PhosphMutase PF10143.4 AIN99660.1 - 0.048 13.3 0.0 0.12 12.0 0.0 1.6 1 0 0 1 1 1 0 2,3-bisphosphoglycerate-independent phosphoglycerate mutase 3HCDH_N PF02737.13 AIN99660.1 - 0.088 12.4 0.1 0.088 12.4 0.1 1.8 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain GIDA PF01134.17 AIN99660.1 - 0.092 11.5 1.0 0.94 8.2 0.1 2.2 2 0 0 2 2 2 0 Glucose inhibited division protein A HI0933_like PF03486.9 AIN99660.1 - 0.13 10.6 0.5 0.27 9.6 0.4 1.5 1 0 0 1 1 1 0 HI0933-like protein NADH-u_ox-rdase PF10785.4 AIN99661.1 - 2.1e-17 63.1 0.6 5.4e-17 61.8 0.4 1.7 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit PAPS_reduct PF01507.14 AIN99663.1 - 1.8e-22 80.0 0.0 6.3e-17 61.9 0.0 2.1 1 1 1 2 2 2 2 Phosphoadenosine phosphosulfate reductase family ATP_bind_3 PF01171.15 AIN99663.1 - 0.048 13.1 0.0 0.062 12.8 0.0 1.2 1 0 0 1 1 1 0 PP-loop family tify PF06200.9 AIN99664.1 - 0.0062 15.7 0.4 0.012 14.8 0.2 1.5 1 0 0 1 1 1 1 tify domain zf-CCCH PF00642.19 AIN99666.1 - 5.8e-07 29.0 8.1 3.1e-05 23.5 0.4 2.8 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-HIT PF04438.11 AIN99666.1 - 6.6e-06 25.6 13.7 2e-05 24.0 9.5 1.9 1 0 0 1 1 1 1 HIT zinc finger RNB PF00773.14 AIN99669.1 - 2e-91 306.6 0.0 3.2e-91 306.0 0.0 1.2 1 0 0 1 1 1 1 RNB domain OB_RNB PF08206.6 AIN99669.1 - 0.097 12.1 0.0 0.26 10.8 0.0 1.7 1 0 0 1 1 1 0 Ribonuclease B OB domain MtN3_slv PF03083.11 AIN99671.1 - 1e-19 70.1 14.0 5.5e-12 45.3 1.1 2.4 3 0 0 3 3 3 2 Sugar efflux transporter for intercellular exchange Tox-ODYAM1 PF15642.1 AIN99671.1 - 0.018 13.7 0.1 0.024 13.3 0.1 1.1 1 0 0 1 1 1 0 Toxin in Odyssella and Amoebophilus ThiF PF00899.16 AIN99672.1 - 0.00071 19.4 0.8 0.001 18.9 0.1 1.6 2 0 0 2 2 2 1 ThiF family Saccharop_dh PF03435.13 AIN99674.1 - 6.5e-28 97.7 0.9 1.7e-27 96.4 0.5 1.7 2 0 0 2 2 2 1 Saccharopine dehydrogenase NAD_binding_10 PF13460.1 AIN99674.1 - 7.2e-05 22.8 0.0 0.00015 21.8 0.0 1.6 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 AIN99674.1 - 0.00044 19.7 0.0 0.00082 18.8 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 AIN99674.1 - 0.00099 17.8 0.0 0.0016 17.2 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Semialdhyde_dh PF01118.19 AIN99674.1 - 0.0024 18.1 0.0 0.0052 17.0 0.0 1.6 1 1 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain adh_short PF00106.20 AIN99674.1 - 0.0082 16.0 0.3 0.024 14.5 0.1 1.8 2 0 0 2 2 2 1 short chain dehydrogenase F420_oxidored PF03807.12 AIN99674.1 - 0.077 13.4 0.0 0.33 11.4 0.0 2.1 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent AAA PF00004.24 AIN99676.1 - 1.6e-40 138.3 0.0 3.4e-40 137.2 0.0 1.6 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 AIN99676.1 - 2.3e-06 27.3 0.1 0.00059 19.5 0.0 3.3 3 1 0 3 3 3 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.7 AIN99676.1 - 8.6e-06 24.9 0.0 1.9e-05 23.8 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 AIN99676.1 - 9.2e-06 25.8 0.3 0.00012 22.2 0.1 2.5 2 1 0 2 2 1 1 AAA domain Vps4_C PF09336.5 AIN99676.1 - 3.6e-05 23.5 0.2 8.1e-05 22.4 0.1 1.6 1 0 0 1 1 1 1 Vps4 C terminal oligomerisation domain AAA_17 PF13207.1 AIN99676.1 - 8.4e-05 23.3 0.6 0.0019 19.0 0.0 2.8 3 1 0 3 3 2 1 AAA domain AAA_19 PF13245.1 AIN99676.1 - 0.0002 21.0 0.9 0.002 17.8 0.0 2.4 2 0 0 2 2 2 1 Part of AAA domain NACHT PF05729.7 AIN99676.1 - 0.00043 19.9 0.0 0.053 13.1 0.0 3.1 4 0 0 4 4 4 1 NACHT domain AAA_33 PF13671.1 AIN99676.1 - 0.0006 19.7 0.0 0.0037 17.1 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 AIN99676.1 - 0.0007 19.6 0.1 0.0048 16.9 0.0 2.3 3 0 0 3 3 2 1 AAA ATPase domain AAA_25 PF13481.1 AIN99676.1 - 0.00071 19.0 0.3 0.048 13.0 0.1 2.4 1 1 1 2 2 2 1 AAA domain AAA_14 PF13173.1 AIN99676.1 - 0.0014 18.5 0.0 0.0046 16.8 0.0 1.8 1 0 0 1 1 1 1 AAA domain KaiC PF06745.8 AIN99676.1 - 0.0018 17.4 0.0 1 8.4 0.0 2.7 2 1 1 3 3 3 1 KaiC Mg_chelatase PF01078.16 AIN99676.1 - 0.0019 17.4 0.0 0.0039 16.3 0.0 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.12 AIN99676.1 - 0.0022 17.4 0.0 0.0056 16.1 0.0 1.6 2 0 0 2 2 1 1 IstB-like ATP binding protein AAA_24 PF13479.1 AIN99676.1 - 0.0044 16.6 0.0 0.008 15.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_2 PF07724.9 AIN99676.1 - 0.0055 16.6 0.0 0.023 14.6 0.0 2.1 2 1 0 2 2 1 1 AAA domain (Cdc48 subfamily) TIP49 PF06068.8 AIN99676.1 - 0.0055 15.4 0.0 0.012 14.3 0.0 1.5 1 0 0 1 1 1 1 TIP49 C-terminus AAA_18 PF13238.1 AIN99676.1 - 0.0076 16.5 0.8 0.041 14.1 0.0 2.5 3 0 0 3 3 2 1 AAA domain RNA_helicase PF00910.17 AIN99676.1 - 0.013 15.6 0.0 0.033 14.3 0.0 1.7 1 0 0 1 1 1 0 RNA helicase Zeta_toxin PF06414.7 AIN99676.1 - 0.016 14.2 0.0 0.032 13.3 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_28 PF13521.1 AIN99676.1 - 0.02 14.8 0.0 0.046 13.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.1 AIN99676.1 - 0.02 14.4 0.0 0.031 13.8 0.0 1.2 1 0 0 1 1 1 0 AAA domain Parvo_NS1 PF01057.12 AIN99676.1 - 0.034 13.0 0.5 0.096 11.5 0.0 1.8 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 Arch_ATPase PF01637.13 AIN99676.1 - 0.043 13.5 0.0 0.58 9.8 0.0 2.3 2 0 0 2 2 2 0 Archaeal ATPase Guanylate_kin PF00625.16 AIN99676.1 - 0.048 13.0 0.0 0.53 9.6 0.0 2.4 2 0 0 2 2 2 0 Guanylate kinase DUF815 PF05673.8 AIN99676.1 - 0.055 12.3 0.0 0.1 11.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_3 PF07726.6 AIN99676.1 - 0.1 12.2 0.0 0.21 11.1 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.11 AIN99676.1 - 0.1 11.8 0.0 0.21 10.7 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein Sigma54_activat PF00158.21 AIN99676.1 - 0.1 12.0 0.0 0.49 9.8 0.0 2.1 2 0 0 2 2 2 0 Sigma-54 interaction domain Fibrillarin_2 PF10113.4 AIN99676.1 - 0.11 10.7 0.0 0.43 8.8 0.0 1.7 2 0 0 2 2 2 0 Fibrillarin-like archaeal protein ABC_tran PF00005.22 AIN99676.1 - 0.14 12.4 0.0 0.27 11.5 0.0 1.5 1 0 0 1 1 1 0 ABC transporter Sigma54_activ_2 PF14532.1 AIN99676.1 - 0.16 12.0 0.0 0.32 11.0 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain RNB PF00773.14 AIN99679.1 - 5.8e-86 288.7 0.0 7.4e-86 288.3 0.0 1.1 1 0 0 1 1 1 1 RNB domain WD40 PF00400.27 AIN99681.1 - 0.033 14.0 3.7 10 6.1 0.1 4.4 5 0 0 5 5 5 0 WD domain, G-beta repeat Carb_anhydrase PF00194.16 AIN99682.1 - 3.3e-19 68.8 0.0 5.3e-19 68.2 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic-type carbonic anhydrase WTF PF03303.8 AIN99682.1 - 0.0036 16.7 0.1 0.0062 15.9 0.1 1.3 1 0 0 1 1 1 1 WTF protein Mucin PF01456.12 AIN99682.1 - 0.8 9.4 23.1 0.27 11.0 11.8 2.5 2 0 0 2 2 2 0 Mucin-like glycoprotein Carboxyl_trans PF01039.17 AIN99684.1 - 1.2e-175 584.5 0.0 1.4e-175 584.3 0.0 1.0 1 0 0 1 1 1 1 Carboxyl transferase domain MdcE PF06833.6 AIN99684.1 - 0.00014 21.1 0.0 0.00029 20.1 0.0 1.4 1 0 0 1 1 1 1 Malonate decarboxylase gamma subunit (MdcE) TPR_11 PF13414.1 AIN99685.1 - 3.1e-12 45.9 0.2 2.8e-07 30.0 0.0 2.5 2 0 0 2 2 2 2 TPR repeat TPR_2 PF07719.12 AIN99685.1 - 1.6e-07 30.7 0.0 0.59 10.1 0.1 3.8 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.23 AIN99685.1 - 8.6e-07 28.3 0.7 0.41 10.3 0.0 3.7 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.1 AIN99685.1 - 0.00015 22.3 4.0 0.00032 21.2 0.4 2.8 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.1 AIN99685.1 - 0.002 18.0 1.2 0.36 10.7 0.1 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat Ecl1 PF12855.2 AIN99685.1 - 0.0026 17.0 2.1 0.0079 15.4 1.5 1.9 1 0 0 1 1 1 1 Life-span regulatory factor zf-MYND PF01753.13 AIN99685.1 - 0.0082 15.9 8.3 0.021 14.6 5.7 1.8 1 0 0 1 1 1 1 MYND finger TPR_14 PF13428.1 AIN99685.1 - 0.0085 16.6 0.3 15 6.5 0.1 3.8 1 1 2 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.1 AIN99685.1 - 0.22 11.3 1.4 70 3.5 0.1 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat Pkinase PF00069.20 AIN99687.1 - 1e-60 205.0 0.0 1.2e-60 204.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AIN99687.1 - 1.7e-38 132.1 0.0 2.1e-38 131.8 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 AIN99687.1 - 6.1e-07 28.6 0.0 8.7e-07 28.1 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 AIN99687.1 - 0.0029 17.3 1.0 0.025 14.3 0.3 2.3 1 1 0 2 2 2 1 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.4 AIN99687.1 - 0.0048 16.2 0.0 0.0085 15.4 0.0 1.3 1 0 0 1 1 1 1 PhoP regulatory network protein YrbL Seadorna_VP7 PF07387.6 AIN99687.1 - 0.02 13.7 0.0 0.032 13.0 0.0 1.4 1 0 0 1 1 1 0 Seadornavirus VP7 Kdo PF06293.9 AIN99687.1 - 0.058 12.4 0.1 0.093 11.7 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family AAA_23 PF13476.1 AIN99688.1 - 1.3e-21 77.8 0.0 1.3e-21 77.8 0.0 5.5 2 1 0 2 2 1 1 AAA domain SMC_N PF02463.14 AIN99688.1 - 1.5e-14 53.7 3.5 2.8e-07 30.0 1.3 2.3 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain SbcCD_C PF13558.1 AIN99688.1 - 6.3e-12 45.2 0.1 2.1e-11 43.5 0.0 1.9 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit AAA_21 PF13304.1 AIN99688.1 - 2.5e-09 37.4 0.0 0.0013 18.8 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_15 PF13175.1 AIN99688.1 - 2.4e-08 33.4 0.4 0.00032 19.8 0.0 2.5 2 1 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.1 AIN99688.1 - 0.00089 18.7 0.0 0.0021 17.5 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain ABC_tran PF00005.22 AIN99688.1 - 0.001 19.3 14.4 0.0032 17.7 0.0 4.9 4 2 0 4 4 4 2 ABC transporter AAA_19 PF13245.1 AIN99688.1 - 0.025 14.3 0.2 0.24 11.1 0.0 2.9 2 0 0 2 2 2 0 Part of AAA domain Rad50_zn_hook PF04423.9 AIN99688.1 - 0.034 13.6 0.0 0.034 13.6 0.0 3.2 3 0 0 3 3 3 0 Rad50 zinc hook motif MobB PF03205.9 AIN99688.1 - 0.045 13.4 0.3 0.55 9.9 0.1 2.8 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B cobW PF02492.14 AIN99688.1 - 0.084 12.3 6.1 0.2 11.0 0.1 3.5 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain Ribosomal_S26e PF01283.14 AIN99689.1 - 2.3e-41 140.6 3.6 2.4e-41 140.5 2.5 1.0 1 0 0 1 1 1 1 Ribosomal protein S26e Rad51 PF08423.6 AIN99690.1 - 1.2e-135 450.3 0.4 1.8e-135 449.7 0.3 1.3 1 0 0 1 1 1 1 Rad51 AAA_25 PF13481.1 AIN99690.1 - 3e-15 56.1 0.0 4.6e-15 55.5 0.0 1.2 1 0 0 1 1 1 1 AAA domain HHH_5 PF14520.1 AIN99690.1 - 4.9e-09 36.2 0.1 1.2e-08 34.9 0.0 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix domain RecA PF00154.16 AIN99690.1 - 1e-08 34.6 0.2 1.6e-08 34.0 0.1 1.2 1 0 0 1 1 1 1 recA bacterial DNA recombination protein KaiC PF06745.8 AIN99690.1 - 4.1e-05 22.8 0.2 8.6e-05 21.7 0.1 1.6 1 1 0 1 1 1 1 KaiC AAA_22 PF13401.1 AIN99690.1 - 0.0034 17.5 0.0 0.0069 16.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain DnaB_C PF03796.10 AIN99690.1 - 0.032 13.1 0.1 0.065 12.0 0.0 1.5 2 0 0 2 2 2 0 DnaB-like helicase C terminal domain PAXNEB PF05625.6 AIN99690.1 - 0.089 11.6 0.0 0.2 10.4 0.0 1.5 2 0 0 2 2 2 0 PAXNEB protein FLO_LFY PF01698.11 AIN99690.1 - 0.12 11.2 0.1 2.5 6.8 0.0 2.3 2 0 0 2 2 2 0 Floricaula / Leafy protein Nucleoside_tran PF01733.13 AIN99691.1 - 3.8e-33 114.9 9.7 3.2e-32 111.9 6.7 2.2 1 1 0 1 1 1 1 Nucleoside transporter Mod_r PF07200.8 AIN99692.1 - 4.6e-05 23.3 0.8 4.6e-05 23.3 0.6 1.6 2 0 0 2 2 2 1 Modifier of rudimentary (Mod(r)) protein Laminin_I PF06008.9 AIN99692.1 - 0.00064 19.1 1.3 0.0012 18.2 0.9 1.4 1 0 0 1 1 1 1 Laminin Domain I Microtub_assoc PF07989.6 AIN99692.1 - 0.011 15.5 0.7 0.032 14.0 0.5 1.8 1 0 0 1 1 1 0 Microtubule associated Leu_zip PF15294.1 AIN99692.1 - 0.016 14.3 0.8 0.025 13.7 0.5 1.3 1 0 0 1 1 1 0 Leucine zipper BLOC1_2 PF10046.4 AIN99692.1 - 0.028 14.5 0.2 0.068 13.3 0.2 1.6 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 ADIP PF11559.3 AIN99692.1 - 0.051 13.4 3.2 0.15 11.9 2.2 1.8 1 1 0 1 1 1 0 Afadin- and alpha -actinin-Binding TMF_DNA_bd PF12329.3 AIN99692.1 - 0.052 13.3 1.5 0.24 11.2 1.2 2.0 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding DUF948 PF06103.6 AIN99692.1 - 0.052 13.4 0.5 0.17 11.7 0.1 1.9 2 0 0 2 2 1 0 Bacterial protein of unknown function (DUF948) GAS PF13851.1 AIN99692.1 - 0.068 12.3 5.3 0.59 9.2 3.5 2.2 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding DUF4201 PF13870.1 AIN99692.1 - 0.084 12.3 3.6 0.053 12.9 1.1 1.7 2 1 0 2 2 2 0 Domain of unknown function (DUF4201) TSC22 PF01166.13 AIN99692.1 - 0.087 12.7 1.2 0.87 9.6 0.3 2.8 2 1 1 3 3 2 0 TSC-22/dip/bun family Gp-FAR-1 PF05823.7 AIN99692.1 - 0.09 12.7 1.2 0.14 12.1 0.3 1.6 2 0 0 2 2 2 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) TBPIP PF07106.8 AIN99692.1 - 0.1 12.1 1.3 0.19 11.2 0.9 1.5 1 0 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Ax_dynein_light PF10211.4 AIN99692.1 - 0.14 11.9 2.6 0.68 9.7 0.9 2.1 1 1 1 2 2 2 0 Axonemal dynein light chain Syntaxin_2 PF14523.1 AIN99692.1 - 0.17 11.9 2.1 1.6 8.8 1.5 2.5 1 1 0 1 1 1 0 Syntaxin-like protein Syntaxin PF00804.20 AIN99692.1 - 0.17 12.0 1.7 0.21 11.7 0.3 1.8 2 0 0 2 2 1 0 Syntaxin bZIP_2 PF07716.10 AIN99692.1 - 0.17 11.6 4.4 0.11 12.2 0.8 2.4 1 1 1 2 2 2 0 Basic region leucine zipper Seryl_tRNA_N PF02403.17 AIN99692.1 - 0.18 11.8 3.3 0.11 12.4 0.5 1.9 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain DivIC PF04977.10 AIN99692.1 - 0.25 10.8 4.4 0.12 11.8 0.7 2.1 2 1 1 3 3 3 0 Septum formation initiator COG2 PF06148.6 AIN99692.1 - 0.32 10.8 1.9 0.26 11.1 0.3 1.6 2 0 0 2 2 1 0 COG (conserved oligomeric Golgi) complex component, COG2 FlaC_arch PF05377.6 AIN99692.1 - 0.5 10.3 5.4 0.18 11.7 0.7 2.5 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) DivIVA PF05103.8 AIN99692.1 - 0.82 9.7 4.9 0.24 11.4 1.0 2.0 2 1 0 2 2 2 0 DivIVA protein Tropomyosin_1 PF12718.2 AIN99692.1 - 1.1 9.1 6.7 0.6 9.9 0.3 2.7 3 0 0 3 3 3 0 Tropomyosin like DUF1664 PF07889.7 AIN99692.1 - 1.7 8.4 4.4 1.1 9.0 0.8 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) Fib_alpha PF08702.5 AIN99692.1 - 9.6 6.3 8.4 6.5 6.8 1.7 3.0 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family Pkinase PF00069.20 AIN99693.1 - 9.5e-57 192.0 0.0 9e-38 129.8 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 AIN99693.1 - 7.2e-22 77.7 0.0 4.7e-20 71.7 0.0 2.2 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.18 AIN99693.1 - 0.0036 17.0 0.1 0.017 14.8 0.0 1.8 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.9 AIN99693.1 - 0.0043 16.1 0.0 0.0078 15.2 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 AIN99693.1 - 0.017 14.1 0.2 2 7.3 0.0 2.4 3 0 0 3 3 3 0 Kinase-like Pox_ser-thr_kin PF05445.6 AIN99693.1 - 0.5 9.0 0.0 0.91 8.2 0.0 1.3 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase SlyX PF04102.7 AIN99694.1 - 0.002 18.4 6.5 0.87 10.0 2.2 3.0 2 0 0 2 2 2 2 SlyX KLRAQ PF10205.4 AIN99694.1 - 0.045 13.7 0.2 0.25 11.4 0.0 2.3 2 0 0 2 2 2 0 Predicted coiled-coil domain-containing protein Med9 PF07544.8 AIN99694.1 - 0.3 10.8 5.5 1.7 8.4 0.7 2.8 3 0 0 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 HALZ PF02183.13 AIN99694.1 - 0.54 10.0 0.1 0.54 10.0 0.0 2.7 3 0 0 3 3 3 0 Homeobox associated leucine zipper ACBP PF00887.14 AIN99695.1 - 0.037 13.6 1.1 0.056 13.1 0.8 1.3 1 0 0 1 1 1 0 Acyl CoA binding protein DUF2462 PF09495.5 AIN99695.1 - 0.48 11.1 11.2 1.4 9.7 6.7 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF2462) DUF2423 PF10338.4 AIN99695.1 - 1.7 8.6 8.8 10 6.1 5.9 2.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2423) Dynein_heavy PF03028.10 AIN99696.1 - 1.9e-213 710.4 0.0 1.1e-212 707.9 0.0 2.2 2 0 0 2 2 2 1 Dynein heavy chain and region D6 of dynein motor DHC_N2 PF08393.8 AIN99696.1 - 2.8e-122 408.1 1.5 2.8e-122 408.1 1.0 2.4 2 0 0 2 2 2 1 Dynein heavy chain, N-terminal region 2 AAA_6 PF12774.2 AIN99696.1 - 5e-89 297.7 0.1 1.9e-88 295.9 0.0 2.0 2 0 0 2 2 2 1 Hydrolytic ATP binding site of dynein motor region D1 AAA_8 PF12780.2 AIN99696.1 - 3.5e-57 193.4 0.1 1.9e-56 190.9 0.0 2.2 2 0 0 2 2 2 1 P-loop containing dynein motor region D4 AAA_9 PF12781.2 AIN99696.1 - 3.8e-53 179.6 0.6 1e-52 178.3 0.4 1.7 1 0 0 1 1 1 1 ATP-binding dynein motor region D5 MT PF12777.2 AIN99696.1 - 1e-45 156.0 2.8 2.3e-45 154.8 2.0 1.6 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_7 PF12775.2 AIN99696.1 - 1.1e-38 132.8 0.0 2.4e-38 131.7 0.0 1.5 1 0 0 1 1 1 1 P-loop containing dynein motor region D3 AAA_5 PF07728.9 AIN99696.1 - 1.4e-13 50.7 0.1 8.5e-05 22.3 0.0 5.9 4 2 0 4 4 4 2 AAA domain (dynein-related subfamily) RNA_helicase PF00910.17 AIN99696.1 - 6.9e-07 29.4 0.1 0.0051 16.9 0.0 3.7 4 0 0 4 4 3 2 RNA helicase AAA_22 PF13401.1 AIN99696.1 - 9.5e-07 29.0 0.1 0.63 10.1 0.0 4.7 3 0 0 3 3 3 1 AAA domain AAA_30 PF13604.1 AIN99696.1 - 2.3e-06 27.3 0.6 0.84 9.1 0.0 3.6 3 0 0 3 3 3 2 AAA domain AAA PF00004.24 AIN99696.1 - 3.6e-05 23.9 0.1 1.2 9.3 0.0 4.4 4 0 0 4 4 3 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 AIN99696.1 - 0.00023 21.9 0.2 0.13 13.0 0.0 4.5 3 0 0 3 3 3 1 AAA domain AAA_16 PF13191.1 AIN99696.1 - 0.00026 21.0 3.7 1.6 8.7 0.0 5.2 6 0 0 6 6 5 2 AAA ATPase domain AAA_18 PF13238.1 AIN99696.1 - 0.00037 20.8 0.1 0.41 10.9 0.0 4.1 3 0 0 3 3 3 1 AAA domain AAA_19 PF13245.1 AIN99696.1 - 0.0013 18.4 2.6 0.96 9.2 0.1 3.7 3 0 0 3 3 3 1 Part of AAA domain AAA_29 PF13555.1 AIN99696.1 - 0.0015 17.9 0.1 0.074 12.5 0.0 3.1 3 0 0 3 3 3 1 P-loop containing region of AAA domain IstB_IS21 PF01695.12 AIN99696.1 - 0.0035 16.7 0.9 4.7 6.5 0.0 3.6 3 0 0 3 3 3 1 IstB-like ATP binding protein T2SE PF00437.15 AIN99696.1 - 0.013 14.4 5.1 0.38 9.6 0.0 4.3 6 0 0 6 6 6 0 Type II/IV secretion system protein AAA_25 PF13481.1 AIN99696.1 - 0.026 13.9 2.7 13 5.1 0.0 4.0 4 0 0 4 4 4 0 AAA domain AAA_33 PF13671.1 AIN99696.1 - 0.041 13.7 2.8 7 6.5 0.0 4.3 3 0 0 3 3 3 0 AAA domain Baculo_PEP_C PF04513.7 AIN99696.1 - 0.055 13.2 6.2 5.2 6.8 0.1 5.1 5 0 0 5 5 5 0 Baculovirus polyhedron envelope protein, PEP, C terminus PhoH PF02562.11 AIN99696.1 - 0.16 11.2 3.5 3 7.0 0.0 3.3 3 0 0 3 3 3 0 PhoH-like protein Mg_chelatase PF01078.16 AIN99696.1 - 0.16 11.1 4.1 0.88 8.6 0.0 3.7 4 0 0 4 4 4 0 Magnesium chelatase, subunit ChlI ABC_tran PF00005.22 AIN99696.1 - 0.23 11.7 0.4 24 5.2 0.0 3.3 2 0 0 2 2 2 0 ABC transporter SRP54 PF00448.17 AIN99696.1 - 1.2 8.5 4.4 9.5 5.6 0.0 3.1 3 0 0 3 3 3 0 SRP54-type protein, GTPase domain Pkinase PF00069.20 AIN99697.1 - 4.1e-52 176.9 0.0 6.9e-52 176.1 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AIN99697.1 - 4.3e-36 124.3 0.0 8.6e-36 123.3 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Chloroa_b-bind PF00504.16 AIN99697.1 - 0.082 13.1 0.0 0.28 11.4 0.0 1.9 1 0 0 1 1 1 0 Chlorophyll A-B binding protein Myc_N PF01056.13 AIN99697.1 - 0.35 9.9 0.0 0.35 9.9 0.0 2.4 2 0 0 2 2 2 0 Myc amino-terminal region ER_lumen_recept PF00810.13 AIN99698.1 - 2.9e-49 167.3 9.7 2.9e-49 167.3 6.7 1.4 2 0 0 2 2 2 1 ER lumen protein retaining receptor ATP_synt_H PF05493.8 AIN99699.1 - 1.6e-21 76.0 5.3 1.8e-21 75.9 3.7 1.0 1 0 0 1 1 1 1 ATP synthase subunit H DUF4131 PF13567.1 AIN99699.1 - 2.2 7.6 6.5 2.2 7.6 4.5 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) WD40 PF00400.27 AIN99700.1 - 2.7e-27 93.5 7.6 4.9e-06 26.2 0.0 6.5 6 0 0 6 6 6 6 WD domain, G-beta repeat Neisseria_PilC PF05567.6 AIN99700.1 - 0.14 11.2 0.0 12 4.8 0.0 3.2 4 0 0 4 4 4 0 Neisseria PilC beta-propeller domain Ank_4 PF13637.1 AIN99703.1 - 1.5e-19 69.9 0.2 2.5e-08 34.2 0.0 3.2 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.2 AIN99703.1 - 6.6e-17 61.6 1.9 1.3e-15 57.5 0.1 1.9 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.1 AIN99703.1 - 2.7e-14 52.8 1.8 4.7e-08 33.0 0.0 2.6 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 AIN99703.1 - 1.5e-13 49.4 0.3 9.2e-05 22.3 0.1 3.4 3 0 0 3 3 3 2 Ankyrin repeat Ank PF00023.25 AIN99703.1 - 2.4e-12 45.9 0.4 0.0001 21.9 0.1 3.2 4 0 0 4 4 4 2 Ankyrin repeat Metallophos PF00149.23 AIN99704.1 - 3.7e-43 147.2 0.2 4.5e-43 146.9 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase BTB_2 PF02214.17 AIN99705.1 - 2.2e-11 43.7 0.0 3.5e-11 43.1 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain DUF4539 PF15072.1 AIN99706.1 - 8.6e-18 63.8 0.0 1.2e-17 63.3 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4539) SNARE_assoc PF09335.6 AIN99707.1 - 2.5e-09 37.3 1.4 2.5e-09 37.3 1.0 3.1 2 1 0 2 2 2 1 SNARE associated Golgi protein EF-hand_5 PF13202.1 AIN99707.1 - 0.0011 18.2 0.0 0.0023 17.1 0.0 1.5 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.1 AIN99707.1 - 0.005 16.6 0.0 0.015 15.1 0.0 1.8 1 0 0 1 1 1 1 EF-hand domain EF-hand_1 PF00036.27 AIN99707.1 - 0.024 13.9 0.0 0.068 12.5 0.0 1.8 1 0 0 1 1 1 0 EF hand EF-hand_7 PF13499.1 AIN99707.1 - 0.11 12.6 0.0 0.26 11.4 0.0 1.6 1 0 0 1 1 1 0 EF-hand domain pair DUF373 PF04123.8 AIN99707.1 - 0.13 11.2 1.8 0.12 11.3 0.1 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF373) Sas10 PF09368.5 AIN99708.1 - 2.3e-21 75.7 6.3 6.1e-21 74.3 4.4 1.8 1 0 0 1 1 1 1 Sas10 C-terminal domain Sas10_Utp3 PF04000.10 AIN99708.1 - 4e-19 68.6 1.2 1.2e-18 67.0 0.8 1.9 1 0 0 1 1 1 1 Sas10/Utp3/C1D family Crl PF07417.7 AIN99709.1 - 0.19 11.4 2.4 0.21 11.2 1.2 1.5 1 1 0 1 1 1 0 Transcriptional regulator Crl SNF2_N PF00176.18 AIN99712.1 - 5.1e-58 196.2 0.2 9.9e-58 195.2 0.1 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 AIN99712.1 - 2e-13 49.9 0.0 4.4e-13 48.9 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-C3HC4_2 PF13923.1 AIN99712.1 - 4.5e-07 29.7 6.8 9.8e-07 28.7 4.7 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 AIN99712.1 - 5e-06 26.0 5.6 9.9e-06 25.1 3.9 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 AIN99712.1 - 6.6e-06 25.7 6.3 1.5e-05 24.6 4.3 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 AIN99712.1 - 8.8e-06 25.2 6.1 2e-05 24.1 4.2 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 AIN99712.1 - 1e-05 25.2 6.1 1e-05 25.2 4.3 1.8 2 0 0 2 2 2 1 Ring finger domain zf-4CXXC_R1 PF10497.4 AIN99712.1 - 0.00017 21.7 6.5 0.00043 20.3 4.5 1.6 1 0 0 1 1 1 1 Zinc-finger domain of monoamine-oxidase A repressor R1 zf-RING_UBOX PF13445.1 AIN99712.1 - 0.00087 18.9 3.0 0.0022 17.6 2.1 1.8 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_4 PF15227.1 AIN99712.1 - 0.0042 16.9 5.7 0.0086 15.9 4.0 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING Sec20 PF03908.8 AIN99712.1 - 0.018 14.7 1.9 0.29 10.8 0.3 2.7 2 0 0 2 2 2 0 Sec20 PAP_assoc PF03828.14 AIN99715.1 - 2.1e-11 43.5 0.0 4.6e-11 42.5 0.0 1.6 1 0 0 1 1 1 1 Cid1 family poly A polymerase DSPc PF00782.15 AIN99716.1 - 1.7e-16 59.9 0.4 8.7e-16 57.7 0.1 2.4 2 1 1 3 3 3 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 AIN99716.1 - 0.045 13.0 0.1 0.075 12.3 0.0 1.3 1 0 0 1 1 1 0 Protein-tyrosine phosphatase EF-hand_7 PF13499.1 AIN99717.1 - 5.3e-15 55.3 1.1 2e-06 27.8 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.27 AIN99717.1 - 2.4e-13 48.3 2.7 2e-06 26.6 0.0 3.9 4 0 0 4 4 4 3 EF hand EF-hand_9 PF14658.1 AIN99717.1 - 4.9e-12 45.5 0.0 1.9e-10 40.5 0.0 2.2 2 0 0 2 2 2 1 EF-hand domain EF-hand_6 PF13405.1 AIN99717.1 - 1.4e-11 43.2 3.7 3.6e-06 26.3 0.0 3.5 3 0 0 3 3 3 2 EF-hand domain EF-hand_8 PF13833.1 AIN99717.1 - 7.5e-08 31.8 3.6 0.00056 19.4 0.1 3.6 2 1 2 4 4 4 4 EF-hand domain pair EF-hand_5 PF13202.1 AIN99717.1 - 8.3e-06 24.9 1.6 0.0074 15.5 0.0 3.6 3 0 0 3 3 3 2 EF hand DDT PF02791.12 AIN99717.1 - 0.042 13.6 0.1 0.56 10.0 0.0 2.3 2 0 0 2 2 2 0 DDT domain EFhand_Ca_insen PF08726.5 AIN99717.1 - 0.059 13.3 0.2 0.27 11.2 0.0 2.1 1 1 1 2 2 2 0 Ca2+ insensitive EF hand RNA_pol_Rpb8 PF03870.10 AIN99718.1 - 1.3e-26 93.4 0.0 1.4e-26 93.2 0.0 1.0 1 0 0 1 1 1 1 RNA polymerase Rpb8 End_beta_barrel PF12195.3 AIN99718.1 - 0.21 11.3 1.2 12 5.7 0.1 2.3 1 1 0 2 2 2 0 Beta barrel domain of bacteriophage endosialidase CSD PF00313.17 AIN99721.1 - 2.7e-16 59.0 0.3 3.6e-16 58.7 0.2 1.2 1 0 0 1 1 1 1 'Cold-shock' DNA-binding domain RCC1_2 PF13540.1 AIN99721.1 - 0.057 13.0 0.0 0.68 9.6 0.0 2.3 2 0 0 2 2 2 0 Regulator of chromosome condensation (RCC1) repeat SKG6 PF08693.5 AIN99723.1 - 0.27 10.5 1.1 0.49 9.7 0.8 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain MCM PF00493.18 AIN99724.1 - 5.6e-130 432.9 0.0 8.7e-130 432.3 0.0 1.3 1 0 0 1 1 1 1 MCM2/3/5 family MCM2_N PF12619.3 AIN99724.1 - 7.5e-15 55.2 25.2 7.5e-15 55.2 17.5 2.9 3 0 0 3 3 3 1 Mini-chromosome maintenance protein 2 MCM_N PF14551.1 AIN99724.1 - 3.2e-14 53.4 4.4 1.7e-13 51.1 0.2 2.7 3 0 0 3 3 3 1 MCM N-terminal domain Mg_chelatase PF01078.16 AIN99724.1 - 8.5e-08 31.6 0.0 1.1e-05 24.7 0.0 2.7 1 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 AIN99724.1 - 4.7e-06 26.3 0.0 1e-05 25.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 AIN99724.1 - 0.0011 18.6 0.0 0.0084 15.7 0.0 2.2 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA PF00004.24 AIN99724.1 - 0.021 15.0 0.0 0.059 13.5 0.0 1.8 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 AIN99724.1 - 0.071 12.5 0.0 0.31 10.5 0.0 1.9 1 1 0 1 1 1 0 Sigma-54 interaction domain CAP_N PF01213.14 AIN99724.1 - 0.18 11.0 0.1 0.37 10.0 0.1 1.5 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Ribonuc_red_lgC PF02867.10 AIN99728.1 - 9.7e-213 707.5 0.0 1.2e-212 707.2 0.0 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, barrel domain Ribonuc_red_lgN PF00317.16 AIN99728.1 - 1.3e-22 79.3 0.1 3.7e-22 77.9 0.0 1.8 1 0 0 1 1 1 1 Ribonucleotide reductase, all-alpha domain ATP-cone PF03477.11 AIN99728.1 - 4e-11 43.2 0.0 1.3e-10 41.5 0.0 1.9 2 0 0 2 2 2 1 ATP cone domain Lebercilin PF15619.1 AIN99729.1 - 0.02 14.3 35.1 0.05 13.0 19.4 3.2 2 1 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease AAA_13 PF13166.1 AIN99729.1 - 0.084 11.3 8.4 0.13 10.6 5.8 1.3 1 0 0 1 1 1 0 AAA domain FlxA PF14282.1 AIN99729.1 - 0.092 12.7 13.3 1.5 8.8 0.0 3.3 3 1 0 3 3 3 0 FlxA-like protein DUF2920 PF11144.3 AIN99729.1 - 0.11 11.5 0.1 0.16 10.9 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2920) Prismane PF03063.15 AIN99729.1 - 0.31 9.3 4.2 0.44 8.8 2.9 1.2 1 0 0 1 1 1 0 Prismane/CO dehydrogenase family IFT57 PF10498.4 AIN99729.1 - 0.35 9.5 14.7 1.3 7.6 9.2 2.2 1 1 1 2 2 2 0 Intra-flagellar transport protein 57 Exo_endo_phos PF03372.18 AIN99730.1 - 0.00011 22.2 0.1 0.71 9.7 0.0 3.8 4 0 0 4 4 4 3 Endonuclease/Exonuclease/phosphatase family EF-hand_5 PF13202.1 AIN99731.1 - 2e-08 33.1 0.5 0.0011 18.2 0.0 2.7 2 0 0 2 2 2 2 EF hand EF-hand_1 PF00036.27 AIN99731.1 - 8.1e-08 31.0 2.2 0.0028 16.8 0.1 3.0 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.1 AIN99731.1 - 1.1e-06 28.0 0.7 0.043 13.7 0.0 3.2 3 0 0 3 3 3 2 EF-hand domain EF-hand_8 PF13833.1 AIN99731.1 - 1.6e-05 24.4 0.3 0.026 14.1 0.0 3.4 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_7 PF13499.1 AIN99731.1 - 0.00022 21.3 0.1 0.0022 18.0 0.0 2.3 1 1 0 1 1 1 1 EF-hand domain pair Dockerin_1 PF00404.13 AIN99731.1 - 0.00084 18.9 2.9 1.6 8.5 0.0 2.6 2 0 0 2 2 2 2 Dockerin type I repeat FG-GAP PF01839.18 AIN99731.1 - 0.37 10.5 2.6 23 4.8 0.0 2.8 3 0 0 3 3 3 0 FG-GAP repeat Raptor_N PF14538.1 AIN99732.1 - 0.026 14.3 0.1 0.043 13.6 0.1 1.3 1 0 0 1 1 1 0 Raptor N-terminal CASPase like domain DUF4381 PF14316.1 AIN99733.1 - 0.27 11.3 0.0 0.27 11.3 0.0 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4381) adh_short PF00106.20 AIN99734.1 - 1.5e-06 28.2 0.2 0.00045 20.1 0.0 3.0 3 0 0 3 3 3 2 short chain dehydrogenase adh_short_C2 PF13561.1 AIN99734.1 - 0.00086 19.1 0.0 1.8 8.2 0.0 2.5 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase Tctex-1 PF03645.8 AIN99735.1 - 4.1e-26 90.7 0.3 4.8e-26 90.5 0.2 1.0 1 0 0 1 1 1 1 Tctex-1 family Ribosomal_S11 PF00411.14 AIN99736.1 - 4.9e-41 139.3 0.6 5.9e-41 139.0 0.4 1.1 1 0 0 1 1 1 1 Ribosomal protein S11 DUF814 PF05670.8 AIN99736.1 - 0.043 13.6 0.0 0.059 13.2 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF814) DUF2252 PF10009.4 AIN99736.1 - 0.072 11.9 0.0 0.088 11.6 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2252) SM-ATX PF14438.1 AIN99737.1 - 0.00023 20.9 0.2 0.0005 19.9 0.1 1.6 1 1 1 2 2 2 1 Ataxin 2 SM domain LSM PF01423.17 AIN99737.1 - 0.0021 17.5 0.1 0.0027 17.2 0.1 1.4 1 1 0 1 1 1 1 LSM domain DUF2642 PF10842.3 AIN99737.1 - 0.14 11.6 0.0 0.24 10.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2642) Serinc PF03348.10 AIN99739.1 - 2.1e-54 184.9 33.0 9.1e-41 139.9 15.8 2.0 1 1 1 2 2 2 2 Serine incorporator (Serinc) Beta-lactamase PF00144.19 AIN99740.1 - 0.0063 15.5 0.7 0.3 10.0 0.3 2.4 2 0 0 2 2 2 2 Beta-lactamase DUF3292 PF11696.3 AIN99740.1 - 0.24 9.2 0.6 0.39 8.5 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3292) Ribosomal_S10 PF00338.17 AIN99741.1 - 5.9e-25 86.9 0.3 6.8e-25 86.7 0.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e PPR_3 PF13812.1 AIN99742.1 - 7.7e-06 25.7 10.0 0.057 13.7 0.0 6.1 7 0 0 7 7 7 3 Pentatricopeptide repeat domain PPR_2 PF13041.1 AIN99742.1 - 9e-06 25.5 0.1 0.28 11.1 0.0 5.1 5 1 1 6 6 6 2 PPR repeat family PPR PF01535.15 AIN99742.1 - 1e-05 25.1 0.5 0.06 13.3 0.0 5.3 6 0 0 6 6 6 1 PPR repeat FlxA PF14282.1 AIN99743.1 - 0.065 13.1 1.3 0.21 11.5 0.9 1.8 1 0 0 1 1 1 0 FlxA-like protein DUF1104 PF06518.6 AIN99747.1 - 0.004 17.2 7.3 0.068 13.3 0.0 3.4 4 0 0 4 4 4 2 Protein of unknown function (DUF1104) HMG_box_2 PF09011.5 AIN99747.1 - 0.006 16.9 3.7 0.38 11.1 0.1 2.8 2 1 0 2 2 2 2 HMG-box domain HMG_box PF00505.14 AIN99747.1 - 0.079 13.2 0.7 11 6.3 0.1 2.5 2 0 0 2 2 2 0 HMG (high mobility group) box AT_hook PF02178.14 AIN99747.1 - 3.3 7.7 9.6 3.6 7.5 3.4 2.8 2 0 0 2 2 2 0 AT hook motif ATP-grasp_4 PF13535.1 AIN99748.1 - 6.1e-24 84.7 0.1 1.1e-16 61.1 0.1 3.3 2 1 1 3 3 3 2 ATP-grasp domain ATPgrasp_Ter PF15632.1 AIN99748.1 - 8.8e-08 31.2 0.0 8.7e-05 21.4 0.0 2.3 2 0 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp_3 PF02655.9 AIN99748.1 - 1e-05 25.4 0.0 9.8e-05 22.2 0.0 2.2 2 0 0 2 2 2 1 ATP-grasp domain GARS_A PF01071.14 AIN99748.1 - 2.8e-05 23.7 0.1 4.9e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain CPSase_L_D2 PF02786.12 AIN99748.1 - 0.00012 21.4 0.0 0.0086 15.3 0.0 2.3 2 0 0 2 2 2 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Dala_Dala_lig_C PF07478.8 AIN99748.1 - 0.14 11.5 0.1 0.24 10.7 0.0 1.3 1 0 0 1 1 1 0 D-ala D-ala ligase C-terminus ubiquitin PF00240.18 AIN99750.1 - 5.5e-05 22.4 0.0 0.0001 21.6 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family PolC_DP2 PF03833.8 AIN99750.1 - 1.4 6.5 8.1 0.14 9.8 1.4 1.9 2 0 0 2 2 2 0 DNA polymerase II large subunit DP2 WD40 PF00400.27 AIN99751.1 - 8.1e-48 158.6 31.1 3.6e-06 26.6 0.0 10.5 10 0 0 10 10 10 10 WD domain, G-beta repeat eIF2A PF08662.6 AIN99751.1 - 1.1e-06 28.5 0.0 0.26 10.9 0.0 3.4 3 0 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A PQQ_2 PF13360.1 AIN99751.1 - 6.1e-05 22.5 1.7 0.019 14.4 0.4 3.5 2 1 2 4 4 4 2 PQQ-like domain Gmad1 PF10647.4 AIN99751.1 - 0.00033 20.1 0.1 0.12 11.8 0.1 2.7 2 0 0 2 2 2 2 Lipoprotein LpqB beta-propeller domain PQQ_3 PF13570.1 AIN99751.1 - 0.00065 19.8 9.3 49 4.3 0.2 7.5 6 1 0 6 6 6 0 PQQ-like domain Nucleoporin_N PF08801.6 AIN99751.1 - 0.042 12.5 0.2 0.17 10.5 0.1 2.2 1 1 1 2 2 2 0 Nup133 N terminal like Amastin PF07344.6 AIN99752.1 - 0.00028 20.5 12.4 0.00033 20.3 8.2 1.4 1 1 0 1 1 1 1 Amastin surface glycoprotein PMP22_Claudin PF00822.15 AIN99752.1 - 0.0046 16.6 10.6 0.0067 16.0 7.3 1.3 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family DUF2207 PF09972.4 AIN99752.1 - 0.47 8.9 3.0 1.4 7.4 1.7 1.9 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) Amastin PF07344.6 AIN99753.1 - 6.3e-34 116.8 25.5 4.6e-24 84.7 4.5 2.5 2 1 1 3 3 3 2 Amastin surface glycoprotein DUF2104 PF09877.4 AIN99753.1 - 4.9 7.1 9.4 3.9 7.5 0.9 3.4 3 0 0 3 3 3 0 Predicted membrane protein (DUF2104) ETF_alpha PF00766.14 AIN99754.1 - 3.2e-36 122.8 1.0 5.4e-36 122.0 0.1 1.9 2 0 0 2 2 2 1 Electron transfer flavoprotein FAD-binding domain ETF PF01012.16 AIN99754.1 - 1.3e-26 93.2 2.7 2.5e-26 92.3 1.9 1.4 1 0 0 1 1 1 1 Electron transfer flavoprotein domain AMP-binding PF00501.23 AIN99755.1 - 9.3e-50 169.2 1.1 3.3e-48 164.1 0.2 2.8 2 1 0 2 2 2 1 AMP-binding enzyme AMP-binding_C PF13193.1 AIN99755.1 - 1.1e-06 29.4 0.4 3e-06 28.0 0.3 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain ATP-synt_C PF00137.16 AIN99757.1 - 3.4e-28 97.3 39.8 1.1e-18 66.8 6.3 3.1 3 0 0 3 3 3 2 ATP synthase subunit C ABC2_membrane_5 PF13346.1 AIN99757.1 - 3.3 6.9 7.8 1.6 7.9 2.8 2.2 2 1 0 2 2 2 0 ABC-2 family transporter protein DUF2592 PF10766.4 AIN99757.1 - 6.9 6.1 13.8 0.11 11.8 3.9 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF2592) LRR_6 PF13516.1 AIN99758.1 - 4.9e-07 29.1 9.4 1.6 9.0 0.1 7.1 7 0 0 7 7 7 2 Leucine Rich repeat LRR_1 PF00560.28 AIN99758.1 - 0.0017 18.0 4.6 53 4.4 0.0 6.3 6 0 0 6 6 6 0 Leucine Rich Repeat LRR_4 PF12799.2 AIN99758.1 - 0.0018 17.8 2.8 3.6 7.3 0.1 5.2 4 1 0 4 4 4 1 Leucine Rich repeats (2 copies) Copine PF07002.11 AIN99761.1 - 3.5e-44 150.0 0.0 6.9e-44 149.1 0.0 1.5 1 0 0 1 1 1 1 Copine C2 PF00168.25 AIN99761.1 - 7e-27 93.0 0.1 1.6e-13 50.2 0.1 2.3 2 0 0 2 2 2 2 C2 domain vWA-TerF-like PF10138.4 AIN99761.1 - 7.7e-08 32.4 0.0 1.3e-07 31.6 0.0 1.4 1 0 0 1 1 1 1 vWA found in TerF C terminus VWA_2 PF13519.1 AIN99761.1 - 0.00013 22.0 0.0 0.0002 21.4 0.0 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.23 AIN99761.1 - 0.0015 18.2 0.0 0.0025 17.5 0.0 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain HSP70 PF00012.15 AIN99762.1 - 1.1e-257 855.8 14.1 1.3e-257 855.6 9.8 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 AIN99762.1 - 8.4e-21 73.9 0.7 2.9e-18 65.5 0.1 2.2 2 0 0 2 2 2 2 MreB/Mbl protein FGGY_C PF02782.11 AIN99762.1 - 8.4e-05 22.2 0.0 0.00026 20.6 0.0 1.9 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain Hydantoinase_A PF01968.13 AIN99762.1 - 0.0018 17.4 0.1 0.0018 17.4 0.0 2.8 4 0 0 4 4 4 1 Hydantoinase/oxoprolinase SpoIIAA-like PF11964.3 AIN99762.1 - 0.39 11.0 2.5 1.2 9.4 0.2 3.0 3 1 1 4 4 4 0 SpoIIAA-like WWE PF02825.15 AIN99764.1 - 0.011 15.1 0.1 0.022 14.1 0.0 1.5 1 0 0 1 1 1 0 WWE domain BIV_Env PF05858.7 AIN99764.1 - 0.15 10.0 0.1 0.21 9.5 0.0 1.1 1 0 0 1 1 1 0 Bovine immunodeficiency virus surface protein (SU) SGL PF08450.7 AIN99765.1 - 1.8e-38 132.2 0.0 8e-38 130.2 0.0 2.1 1 1 0 1 1 1 1 SMP-30/Gluconolaconase/LRE-like region FAD_binding_1 PF00667.15 AIN99766.1 - 1.9e-40 138.6 0.0 2.8e-40 138.0 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.20 AIN99766.1 - 4.5e-34 117.4 0.7 2.4e-33 115.1 0.2 2.2 2 0 0 2 2 2 1 Flavodoxin NAD_binding_1 PF00175.16 AIN99766.1 - 5.6e-14 52.6 0.0 1.8e-13 50.9 0.0 1.9 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain Flavodoxin_NdrI PF07972.6 AIN99766.1 - 0.13 12.2 0.0 0.22 11.4 0.0 1.4 1 0 0 1 1 1 0 NrdI Flavodoxin like DUF4201 PF13870.1 AIN99767.1 - 0.066 12.6 11.5 0.019 14.4 5.6 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4201) DUF2664 PF10867.3 AIN99767.1 - 0.24 12.0 8.6 0.33 11.5 4.9 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2664) APG6 PF04111.7 AIN99767.1 - 1.1 8.2 10.6 1.7 7.6 7.3 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 IncA PF04156.9 AIN99767.1 - 8.3 5.9 13.9 14 5.2 9.6 1.3 1 0 0 1 1 1 0 IncA protein FUSC PF04632.7 AIN99767.1 - 8.5 4.6 7.9 12 4.1 5.4 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family CwfJ_C_1 PF04677.10 AIN99768.1 - 0.058 13.0 0.3 0.11 12.1 0.2 1.5 1 0 0 1 1 1 0 Protein similar to CwfJ C-terminus 1 DnaJ PF00226.26 AIN99769.1 - 2e-16 59.4 0.8 3.5e-16 58.6 0.6 1.5 1 0 0 1 1 1 1 DnaJ domain Biopterin_H PF00351.16 AIN99770.1 - 3.5e-123 410.6 0.0 4.5e-123 410.2 0.0 1.1 1 0 0 1 1 1 1 Biopterin-dependent aromatic amino acid hydroxylase zf-C3HC4_3 PF13920.1 AIN99772.1 - 5.7e-06 25.9 6.8 9.4e-06 25.2 4.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 AIN99772.1 - 8.1e-06 25.4 7.6 1.3e-05 24.8 5.2 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 AIN99772.1 - 1e-05 25.4 11.1 1.7e-05 24.7 7.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 AIN99772.1 - 2.8e-05 23.6 8.4 4.8e-05 22.9 5.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 AIN99772.1 - 0.00029 20.6 10.9 0.00049 19.8 7.5 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_4 PF15227.1 AIN99772.1 - 0.00076 19.3 12.4 0.0013 18.5 8.6 1.4 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 AIN99772.1 - 0.0011 18.6 4.6 0.0025 17.4 3.2 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_6 PF14835.1 AIN99772.1 - 0.11 12.3 5.0 0.27 11.0 3.4 1.7 1 1 0 1 1 1 0 zf-RING of BARD1-type protein Baculo_IE-1 PF05290.6 AIN99772.1 - 0.39 10.4 3.6 0.2 11.3 0.2 2.0 2 0 0 2 2 2 0 Baculovirus immediate-early protein (IE-0) Imm5 PF14423.1 AIN99772.1 - 0.44 10.1 2.5 1.7 8.2 1.0 2.0 2 0 0 2 2 2 0 Immunity protein Imm5 TF_Zn_Ribbon PF08271.7 AIN99772.1 - 0.7 9.2 3.7 4.1 6.8 0.2 2.4 2 0 0 2 2 2 0 TFIIB zinc-binding zf-rbx1 PF12678.2 AIN99772.1 - 0.91 9.6 4.3 1.8 8.7 3.0 1.5 1 0 0 1 1 1 0 RING-H2 zinc finger zf-HIT PF04438.11 AIN99772.1 - 1.3 8.7 7.5 0.91 9.2 2.1 2.2 2 0 0 2 2 2 0 HIT zinc finger zf-C2H2 PF00096.21 AIN99772.1 - 3.1 8.3 5.4 7.6 7.1 0.0 2.8 3 0 0 3 3 2 0 Zinc finger, C2H2 type zf-RING_4 PF14570.1 AIN99772.1 - 3.9 7.1 8.1 7.4 6.2 5.6 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Mnd1 PF03962.10 AIN99772.1 - 4.7 6.8 11.7 1.8 8.1 1.3 2.8 2 1 1 3 3 3 0 Mnd1 family zf-MIZ PF02891.15 AIN99772.1 - 4.9 6.7 8.0 8.5 5.9 5.5 1.4 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger DEAD PF00270.24 AIN99773.1 - 1.6e-39 135.1 0.0 5.7e-39 133.3 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 AIN99773.1 - 1.8e-21 75.7 0.6 7.3e-21 73.8 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DUF4217 PF13959.1 AIN99773.1 - 1.4e-15 56.5 0.1 3.1e-15 55.4 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.10 AIN99773.1 - 0.002 18.0 0.0 0.0095 15.7 0.0 2.1 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DUF2753 PF10952.3 AIN99773.1 - 0.0029 17.5 0.1 0.0063 16.5 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2753) UbiA PF01040.13 AIN99774.1 - 3e-26 92.1 20.0 4.6e-26 91.5 13.8 1.4 1 0 0 1 1 1 1 UbiA prenyltransferase family LRR_4 PF12799.2 AIN99775.1 - 0.018 14.6 0.0 1.6 8.4 0.0 2.6 2 0 0 2 2 2 0 Leucine Rich repeats (2 copies) Hydrolase_3 PF08282.7 AIN99776.1 - 3.8e-28 98.7 0.0 3.4e-26 92.3 0.0 2.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase S6PP PF05116.8 AIN99776.1 - 1.3e-07 31.2 0.0 2e-06 27.2 0.0 2.2 2 0 0 2 2 2 1 Sucrose-6F-phosphate phosphohydrolase Hydrolase_3 PF08282.7 AIN99777.1 - 1e-35 123.5 0.0 1.4e-34 119.8 0.0 2.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase S6PP PF05116.8 AIN99777.1 - 5.7e-09 35.6 0.0 1.6e-06 27.6 0.0 2.4 2 0 0 2 2 2 2 Sucrose-6F-phosphate phosphohydrolase Hydrolase PF00702.21 AIN99777.1 - 0.00065 20.1 3.7 0.15 12.4 1.2 2.3 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase HAD PF12710.2 AIN99777.1 - 0.0017 18.5 0.7 0.072 13.2 0.5 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase DUF4438 PF14505.1 AIN99777.1 - 0.063 12.0 0.0 0.11 11.2 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4438) Hydrolase_3 PF08282.7 AIN99778.1 - 5.7e-52 176.8 0.0 7.1e-52 176.5 0.0 1.1 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase S6PP PF05116.8 AIN99778.1 - 4.3e-16 58.9 0.0 1.5e-07 31.0 0.0 2.2 2 0 0 2 2 2 2 Sucrose-6F-phosphate phosphohydrolase Hydrolase PF00702.21 AIN99778.1 - 1.6e-07 31.9 0.7 1.8e-06 28.5 0.5 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 AIN99778.1 - 0.00072 19.7 0.9 0.087 12.9 0.0 2.7 1 1 1 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.1 AIN99778.1 - 0.02 14.7 0.0 0.085 12.7 0.0 2.2 1 1 0 1 1 1 0 Haloacid dehalogenase-like hydrolase Bmp PF02608.9 AIN99778.1 - 0.031 13.0 0.0 0.41 9.3 0.0 2.1 2 0 0 2 2 2 0 Basic membrane protein DUF460 PF04312.8 AIN99778.1 - 0.1 12.1 0.0 0.19 11.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF460) Hydrolase_3 PF08282.7 AIN99779.1 - 3e-49 167.9 0.0 3.5e-49 167.6 0.0 1.0 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase S6PP PF05116.8 AIN99779.1 - 1.4e-17 63.7 0.0 6.9e-09 35.3 0.0 2.1 2 0 0 2 2 2 2 Sucrose-6F-phosphate phosphohydrolase Hydrolase PF00702.21 AIN99779.1 - 3e-06 27.7 0.0 1.2e-05 25.8 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 AIN99779.1 - 0.0016 18.6 0.2 0.075 13.1 0.1 2.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.1 AIN99779.1 - 0.0053 16.6 0.0 0.02 14.7 0.0 2.0 2 1 0 2 2 2 1 Haloacid dehalogenase-like hydrolase MAF_flag10 PF01973.13 AIN99779.1 - 0.13 11.7 0.0 0.23 10.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function DUF115 Hydrolase_3 PF08282.7 AIN99780.1 - 3.1e-49 167.8 0.0 4e-33 115.0 0.0 2.1 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase S6PP PF05116.8 AIN99780.1 - 4.3e-16 58.9 0.0 4.3e-11 42.5 0.0 2.3 2 0 0 2 2 2 2 Sucrose-6F-phosphate phosphohydrolase Hydrolase PF00702.21 AIN99780.1 - 1.9e-06 28.4 0.0 0.057 13.8 0.0 2.3 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase HAD PF12710.2 AIN99780.1 - 0.00041 20.5 0.0 0.01 15.9 0.0 2.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 AIN99780.1 - 0.044 13.9 0.0 0.74 10.0 0.0 2.5 3 0 0 3 3 3 0 Haloacid dehalogenase-like hydrolase X PF00739.14 AIN99780.1 - 0.098 12.5 0.3 0.19 11.6 0.2 1.4 1 0 0 1 1 1 0 Trans-activation protein X Hydrolase_6 PF13344.1 AIN99780.1 - 0.11 12.3 0.0 0.25 11.2 0.0 1.6 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 AIN99781.1 - 5.3e-39 134.3 0.1 1.6e-21 77.0 0.0 3.7 3 1 0 3 3 3 3 haloacid dehalogenase-like hydrolase S6PP PF05116.8 AIN99781.1 - 4.5e-15 55.6 0.1 3.4e-08 33.0 0.0 2.2 2 0 0 2 2 2 2 Sucrose-6F-phosphate phosphohydrolase HAD PF12710.2 AIN99781.1 - 0.0013 18.9 0.1 0.038 14.1 0.1 2.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 AIN99781.1 - 0.028 14.8 0.0 1.8 8.9 0.0 2.2 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase Complex1_49kDa PF00346.14 AIN99781.1 - 0.16 10.8 0.0 0.29 10.0 0.0 1.3 1 0 0 1 1 1 0 Respiratory-chain NADH dehydrogenase, 49 Kd subunit Amastin PF07344.6 AIN99782.1 - 3.6e-50 169.5 7.2 5.1e-50 169.0 5.0 1.2 1 0 0 1 1 1 1 Amastin surface glycoprotein Amastin PF07344.6 AIN99783.1 - 5.7e-35 120.2 12.4 1e-34 119.4 8.6 1.4 1 0 0 1 1 1 1 Amastin surface glycoprotein PEN-2 PF10251.4 AIN99783.1 - 0.014 15.6 0.3 0.037 14.2 0.2 1.7 1 0 0 1 1 1 0 Presenilin enhancer-2 subunit of gamma secretase DUF1345 PF07077.6 AIN99783.1 - 1.4 8.3 8.1 0.1 12.1 1.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1345) Phtf-FEM1B_bdg PF12129.3 AIN99783.1 - 2.5 7.4 10.1 1.2 8.4 0.9 2.2 2 0 0 2 2 2 0 Male germ-cell putative homeodomain transcription factor zf-CCCH PF00642.19 AIN99784.1 - 9.1e-06 25.2 6.3 1.9e-05 24.2 3.7 2.0 2 0 0 2 2 2 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) IMS PF00817.15 AIN99785.1 - 3e-35 121.1 0.1 5.9e-35 120.2 0.1 1.5 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.3 AIN99785.1 - 9.7e-13 48.1 0.2 2.1e-12 47.1 0.2 1.4 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.3 AIN99785.1 - 1.2e-05 25.0 0.0 2.7e-05 23.9 0.0 1.6 1 0 0 1 1 1 1 IMS family HHH motif HHH_5 PF14520.1 AIN99785.1 - 0.012 15.7 1.3 0.065 13.4 0.0 2.8 3 0 0 3 3 3 0 Helix-hairpin-helix domain IMS PF00817.15 AIN99786.1 - 9.7e-39 132.5 0.0 2.2e-38 131.3 0.0 1.6 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.3 AIN99786.1 - 1e-18 67.4 0.1 2.4e-18 66.2 0.1 1.6 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.3 AIN99786.1 - 0.00015 21.6 0.0 0.00045 20.0 0.0 1.9 1 0 0 1 1 1 1 IMS family HHH motif IMS PF00817.15 AIN99788.1 - 0.16 11.7 1.4 6.6 6.5 1.0 2.9 1 1 0 1 1 1 0 impB/mucB/samB family AAA PF00004.24 AIN99790.1 - 1.2e-31 109.6 0.0 1.8e-28 99.3 0.0 3.3 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 AIN99790.1 - 1.2e-08 35.1 0.0 5.1e-05 23.4 0.0 3.3 2 1 0 2 2 2 2 AAA domain IstB_IS21 PF01695.12 AIN99790.1 - 2e-08 33.8 0.0 1.4e-05 24.5 0.0 2.6 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_5 PF07728.9 AIN99790.1 - 4.3e-08 32.9 0.0 3.3e-06 26.8 0.0 2.5 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_17 PF13207.1 AIN99790.1 - 4.7e-08 33.8 0.0 2e-05 25.4 0.0 2.7 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.1 AIN99790.1 - 9.1e-08 32.2 2.4 0.0032 17.4 0.0 4.4 3 2 0 3 3 3 2 AAA ATPase domain AAA_14 PF13173.1 AIN99790.1 - 3.9e-07 30.0 0.0 8.7e-06 25.6 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.1 AIN99790.1 - 4.5e-07 29.8 0.0 0.0022 17.9 0.0 2.8 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.17 AIN99790.1 - 6.8e-06 26.2 0.0 0.0072 16.4 0.0 2.4 2 0 0 2 2 2 1 RNA helicase RuvB_N PF05496.7 AIN99790.1 - 1.2e-05 24.5 0.0 2.9e-05 23.2 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus Mg_chelatase PF01078.16 AIN99790.1 - 4.3e-05 22.7 0.0 0.0019 17.4 0.0 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_19 PF13245.1 AIN99790.1 - 6.7e-05 22.5 1.3 0.0099 15.6 0.1 3.3 2 1 0 2 2 2 1 Part of AAA domain DUF815 PF05673.8 AIN99790.1 - 0.00018 20.5 0.0 0.0029 16.5 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_25 PF13481.1 AIN99790.1 - 0.00019 20.8 0.0 0.003 16.9 0.0 2.5 2 1 0 3 3 2 1 AAA domain Zeta_toxin PF06414.7 AIN99790.1 - 0.00031 19.8 0.0 0.064 12.3 0.0 2.3 2 0 0 2 2 2 1 Zeta toxin Arch_ATPase PF01637.13 AIN99790.1 - 0.00039 20.1 0.0 0.23 11.1 0.0 3.1 2 1 0 2 2 2 1 Archaeal ATPase AAA_2 PF07724.9 AIN99790.1 - 0.00049 20.0 0.0 0.015 15.1 0.0 2.3 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) TniB PF05621.6 AIN99790.1 - 0.00066 18.5 0.0 0.0051 15.6 0.0 2.3 2 0 0 2 2 2 1 Bacterial TniB protein NACHT PF05729.7 AIN99790.1 - 0.0021 17.7 0.0 0.017 14.8 0.0 2.4 2 0 0 2 2 2 1 NACHT domain TIP49 PF06068.8 AIN99790.1 - 0.0021 16.8 0.0 0.0038 16.0 0.0 1.3 1 0 0 1 1 1 1 TIP49 C-terminus AAA_28 PF13521.1 AIN99790.1 - 0.0051 16.7 0.0 0.07 13.0 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_24 PF13479.1 AIN99790.1 - 0.0065 16.0 0.2 0.016 14.8 0.1 1.6 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.1 AIN99790.1 - 0.0073 15.9 0.0 1.2 8.6 0.0 2.4 2 0 0 2 2 2 1 AAA domain T2SE PF00437.15 AIN99790.1 - 0.01 14.7 0.0 0.56 9.0 0.0 2.7 2 1 0 2 2 2 1 Type II/IV secretion system protein AAA_29 PF13555.1 AIN99790.1 - 0.01 15.3 0.0 1.8 8.1 0.0 2.6 2 0 0 2 2 2 0 P-loop containing region of AAA domain MCM PF00493.18 AIN99790.1 - 0.013 14.3 0.0 0.11 11.2 0.0 2.1 2 0 0 2 2 2 0 MCM2/3/5 family ABC_tran PF00005.22 AIN99790.1 - 0.02 15.2 0.0 0.11 12.8 0.0 2.1 2 0 0 2 2 2 0 ABC transporter PhoH PF02562.11 AIN99790.1 - 0.02 14.1 0.0 0.056 12.6 0.0 1.7 1 0 0 1 1 1 0 PhoH-like protein AAA_3 PF07726.6 AIN99790.1 - 0.025 14.1 0.0 0.053 13.1 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 AIN99790.1 - 0.027 13.9 0.0 0.17 11.3 0.0 2.1 2 0 0 2 2 2 0 Sigma-54 interaction domain SKI PF01202.17 AIN99790.1 - 0.032 14.1 0.0 0.076 12.8 0.0 1.7 1 1 0 1 1 1 0 Shikimate kinase AAA_18 PF13238.1 AIN99790.1 - 0.037 14.3 0.0 0.12 12.6 0.0 1.8 2 0 0 2 2 1 0 AAA domain UPF0079 PF02367.12 AIN99790.1 - 0.037 13.6 0.0 0.23 11.0 0.0 2.1 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 AAA_10 PF12846.2 AIN99790.1 - 0.037 13.4 0.0 3.3 7.0 0.0 3.3 3 1 1 4 4 4 0 AAA-like domain Parvo_NS1 PF01057.12 AIN99790.1 - 0.039 12.8 0.0 0.091 11.6 0.0 1.5 2 0 0 2 2 1 0 Parvovirus non-structural protein NS1 CPT PF07931.7 AIN99790.1 - 0.049 13.2 0.1 1.7 8.2 0.0 3.0 4 0 0 4 4 4 0 Chloramphenicol phosphotransferase-like protein Guanylate_kin PF00625.16 AIN99790.1 - 0.063 12.7 0.0 0.27 10.6 0.0 1.9 2 0 0 2 2 2 0 Guanylate kinase Sigma54_activ_2 PF14532.1 AIN99790.1 - 0.083 12.9 0.0 0.32 11.0 0.0 2.0 2 0 0 2 2 1 0 Sigma-54 interaction domain KTI12 PF08433.5 AIN99790.1 - 0.098 11.8 0.0 1.3 8.1 0.0 2.3 2 0 0 2 2 2 0 Chromatin associated protein KTI12 SNARE PF05739.14 AIN99791.1 - 1.5e-14 53.3 1.4 1.5e-14 53.3 0.9 2.2 2 0 0 2 2 2 1 SNARE domain Syntaxin PF00804.20 AIN99791.1 - 8.5e-05 22.6 12.9 0.00014 21.9 2.6 2.6 2 1 1 3 3 3 3 Syntaxin DASH_Dad4 PF08650.5 AIN99791.1 - 0.11 12.4 8.8 0.092 12.6 2.3 2.5 2 1 0 2 2 2 0 DASH complex subunit Dad4 Herpes_US9 PF06072.6 AIN99791.1 - 0.18 11.6 1.1 0.37 10.6 0.8 1.4 1 0 0 1 1 1 0 Alphaherpesvirus tegument protein US9 AKNA PF12443.3 AIN99791.1 - 0.25 11.3 1.9 0.69 9.9 0.2 2.3 2 1 0 2 2 2 0 AT-hook-containing transcription factor ETRAMP PF09716.5 AIN99791.1 - 3.8 7.5 5.6 0.79 9.7 0.6 2.4 2 2 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) DUF423 PF04241.10 AIN99792.1 - 8.7e-19 67.2 2.0 1.3e-18 66.7 1.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF423) DUF423 PF04241.10 AIN99793.1 - 1.1e-21 76.5 0.9 1.5e-21 76.1 0.7 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF423) NADH-u_ox-rdase PF10785.4 AIN99793.1 - 0.0061 16.7 0.4 0.011 15.9 0.2 1.4 1 1 0 1 1 1 1 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit Peptidase_A8 PF01252.13 AIN99793.1 - 0.079 12.5 0.1 0.12 12.0 0.1 1.2 1 0 0 1 1 1 0 Signal peptidase (SPase) II GerA PF03323.8 AIN99793.1 - 0.11 10.5 0.3 0.19 9.7 0.1 1.4 2 0 0 2 2 2 0 Bacillus/Clostridium GerA spore germination protein DUF423 PF04241.10 AIN99794.1 - 1e-22 79.7 3.6 1.6e-22 79.2 2.5 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF423) DUF3277 PF11681.3 AIN99794.1 - 0.027 13.9 0.0 0.033 13.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3277) MerC PF03203.9 AIN99794.1 - 0.71 10.2 6.0 32 4.9 4.2 2.2 1 1 0 1 1 1 0 MerC mercury resistance protein DUF4402 PF14352.1 AIN99795.1 - 0.035 14.5 0.1 0.042 14.3 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4402) Reo_sigmaC PF04582.7 AIN99796.1 - 0.02 14.1 19.6 3 6.9 1.9 4.4 2 2 3 5 5 5 0 Reovirus sigma C capsid protein NPV_P10 PF05531.7 AIN99796.1 - 0.55 10.5 14.7 0.29 11.4 0.5 5.1 5 0 0 5 5 5 0 Nucleopolyhedrovirus P10 protein DEAD PF00270.24 AIN99797.1 - 1.2e-43 148.5 0.0 1.8e-41 141.4 0.0 2.1 2 0 0 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.26 AIN99797.1 - 4e-27 93.8 0.1 1e-26 92.5 0.1 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain CMS1 PF14617.1 AIN99797.1 - 0.0032 16.5 0.0 0.0075 15.3 0.0 1.5 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit AAA_19 PF13245.1 AIN99797.1 - 0.036 13.7 0.3 0.21 11.3 0.0 2.4 2 1 1 3 3 3 0 Part of AAA domain AAA_22 PF13401.1 AIN99797.1 - 0.038 14.1 0.0 0.14 12.2 0.0 1.9 2 0 0 2 2 2 0 AAA domain Pol_alpha_B_N PF08418.5 AIN99798.1 - 3.8 6.9 11.0 0.06 12.8 1.7 2.3 3 0 0 3 3 3 0 DNA polymerase alpha subunit B N-terminal Coa1 PF08695.5 AIN99799.1 - 0.0029 17.0 0.0 0.01 15.3 0.0 1.9 2 0 0 2 2 2 1 Cytochrome oxidase complex assembly protein 1 CoA_binding_3 PF13727.1 AIN99799.1 - 0.02 14.7 0.4 0.029 14.2 0.3 1.2 1 0 0 1 1 1 0 CoA-binding domain Abhydrolase_6 PF12697.2 AIN99801.1 - 8.3e-28 97.8 0.2 1e-27 97.4 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 AIN99801.1 - 6.6e-19 68.3 0.0 1.8e-18 66.9 0.0 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 AIN99801.1 - 7.9e-17 61.3 0.0 1.1e-16 60.8 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 AIN99801.1 - 8.7e-06 25.1 0.0 0.0052 16.0 0.0 2.9 3 1 0 3 3 3 1 Prolyl oligopeptidase family DLH PF01738.13 AIN99801.1 - 5.3e-05 22.6 0.0 0.0081 15.4 0.0 2.4 2 0 0 2 2 2 1 Dienelactone hydrolase family Abhydrolase_2 PF02230.11 AIN99801.1 - 0.00011 21.7 0.0 0.0009 18.7 0.0 2.1 2 1 0 2 2 2 1 Phospholipase/Carboxylesterase FSH1 PF03959.8 AIN99801.1 - 0.00067 19.1 0.0 0.0019 17.6 0.0 1.7 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_4 PF08386.5 AIN99801.1 - 0.00071 19.4 0.0 0.0013 18.5 0.0 1.4 1 0 0 1 1 1 1 TAP-like protein Peptidase_S15 PF02129.13 AIN99801.1 - 0.00098 18.6 0.0 0.16 11.3 0.0 2.1 2 0 0 2 2 2 2 X-Pro dipeptidyl-peptidase (S15 family) Hydrolase_4 PF12146.3 AIN99801.1 - 0.003 17.3 0.0 0.0063 16.3 0.0 1.6 1 0 0 1 1 1 1 Putative lysophospholipase Ndr PF03096.9 AIN99801.1 - 0.004 15.6 0.2 0.009 14.5 0.1 1.5 1 1 0 1 1 1 1 Ndr family BAAT_C PF08840.6 AIN99801.1 - 0.11 12.2 0.0 0.27 10.9 0.0 1.6 1 1 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal TPP_enzyme_N PF02776.13 AIN99802.1 - 1.7e-14 53.6 1.9 9.9e-14 51.1 0.0 2.4 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.16 AIN99802.1 - 1.6e-10 40.7 5.0 2.8e-09 36.7 1.0 3.3 2 1 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Kelch_3 PF13415.1 AIN99803.1 - 2.2e-17 62.6 2.7 2.7e-06 27.3 0.0 4.2 4 1 0 4 4 4 3 Galactose oxidase, central domain Kelch_6 PF13964.1 AIN99803.1 - 2.5e-13 49.5 0.0 0.00028 20.9 0.0 5.4 5 0 0 5 5 5 3 Kelch motif Kelch_4 PF13418.1 AIN99803.1 - 7.9e-12 44.7 0.8 0.00031 20.4 0.0 3.9 3 0 0 3 3 3 3 Galactose oxidase, central domain Kelch_5 PF13854.1 AIN99803.1 - 4.6e-11 42.4 0.8 4.4e-06 26.5 0.0 4.6 4 0 0 4 4 4 1 Kelch motif Kelch_2 PF07646.10 AIN99803.1 - 6.3e-09 35.2 3.2 0.0022 17.7 0.0 4.2 4 0 0 4 4 4 3 Kelch motif Kelch_1 PF01344.20 AIN99803.1 - 1.3e-08 34.2 0.5 0.00042 19.7 0.0 4.3 4 0 0 4 4 4 2 Kelch motif DUF2784 PF10861.3 AIN99803.1 - 0.12 12.2 0.0 0.35 10.6 0.0 1.8 1 0 0 1 1 1 0 Protein of Unknown function (DUF2784) Helicase_C_2 PF13307.1 AIN99804.1 - 8.6e-41 139.6 0.0 1.7e-40 138.7 0.0 1.5 1 0 0 1 1 1 1 Helicase C-terminal domain DEAD_2 PF06733.10 AIN99804.1 - 9.8e-36 122.7 0.0 2.1e-35 121.7 0.0 1.5 1 0 0 1 1 1 1 DEAD_2 DEAD PF00270.24 AIN99804.1 - 0.00023 20.6 0.0 0.092 12.2 0.0 2.5 2 0 0 2 2 2 2 DEAD/DEAH box helicase ResIII PF04851.10 AIN99804.1 - 0.011 15.5 0.0 3.1 7.6 0.0 2.6 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit TruD PF01142.13 AIN99806.1 - 3.6e-42 144.3 0.0 2.5e-40 138.3 0.0 2.4 2 0 0 2 2 2 2 tRNA pseudouridine synthase D (TruD) DUF3342 PF11822.3 AIN99808.1 - 7.3e-136 452.4 0.0 9.2e-136 452.1 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3342) Pkinase PF00069.20 AIN99810.1 - 0.014 14.5 0.0 1.3 8.0 0.0 2.4 1 1 1 2 2 2 0 Protein kinase domain Pkinase_Tyr PF07714.12 AIN99810.1 - 0.16 10.9 0.0 3.8 6.5 0.0 2.2 2 0 0 2 2 2 0 Protein tyrosine kinase Pkinase PF00069.20 AIN99812.1 - 2.6e-64 216.8 0.0 3.5e-64 216.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AIN99812.1 - 4.4e-34 117.7 0.0 6.4e-34 117.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Lipocalin_5 PF13924.1 AIN99812.1 - 1e-27 96.5 0.0 1.9e-27 95.6 0.0 1.4 1 0 0 1 1 1 1 Lipocalin-like domain PX PF00787.19 AIN99812.1 - 6.4e-14 51.7 0.2 1.3e-13 50.7 0.1 1.5 1 0 0 1 1 1 1 PX domain Kinase-like PF14531.1 AIN99812.1 - 5e-05 22.4 0.0 8.5e-05 21.6 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 AIN99812.1 - 0.00055 19.7 3.0 0.0032 17.2 0.2 3.0 2 1 1 3 3 3 1 Phosphotransferase enzyme family FYVE PF01363.16 AIN99812.1 - 0.013 15.3 7.9 0.033 14.0 5.2 1.9 1 1 0 1 1 1 0 FYVE zinc finger RIO1 PF01163.17 AIN99812.1 - 0.035 13.4 0.0 0.062 12.6 0.0 1.3 1 0 0 1 1 1 0 RIO1 family Kdo PF06293.9 AIN99812.1 - 0.27 10.2 0.2 0.58 9.1 0.0 1.6 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Sulfate_transp PF00916.15 AIN99813.1 - 6.8e-33 113.8 7.7 1.2e-32 113.0 5.3 1.3 1 0 0 1 1 1 1 Sulfate transporter family His_Phos_2 PF00328.17 AIN99813.1 - 1.5e-15 57.3 0.0 1.1e-14 54.4 0.0 2.1 2 0 0 2 2 2 1 Histidine phosphatase superfamily (branch 2) Sulfate_tra_GLY PF13792.1 AIN99813.1 - 4.8e-14 51.7 5.1 1.5e-13 50.1 3.6 1.9 1 0 0 1 1 1 1 Sulfate transporter N-terminal domain with GLY motif STAS PF01740.16 AIN99813.1 - 5.4e-08 32.2 0.0 1.1e-07 31.2 0.0 1.5 1 0 0 1 1 1 1 STAS domain zf-HIT PF04438.11 AIN99814.1 - 0.052 13.2 5.8 0.11 12.1 4.0 1.5 1 0 0 1 1 1 0 HIT zinc finger zf-B_box PF00643.19 AIN99814.1 - 0.062 13.1 0.3 0.14 12.0 0.2 1.6 1 0 0 1 1 1 0 B-box zinc finger PC_rep PF01851.17 AIN99817.1 - 3.3e-14 52.2 9.7 0.088 13.0 0.0 8.5 9 0 0 9 9 9 3 Proteasome/cyclosome repeat HEAT_2 PF13646.1 AIN99817.1 - 1.2e-13 51.1 2.3 1.5e-09 37.9 0.0 4.5 3 1 1 4 4 4 2 HEAT repeats HEAT PF02985.17 AIN99817.1 - 0.0024 17.8 2.6 51 4.3 0.0 5.5 5 0 0 5 5 5 0 HEAT repeat TPR_8 PF13181.1 AIN99817.1 - 0.012 15.3 2.5 15 5.6 0.0 5.0 5 0 0 5 5 5 0 Tetratricopeptide repeat DEC-1_N PF04625.8 AIN99817.1 - 0.11 11.1 2.5 0.19 10.3 1.7 1.3 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region TPR_2 PF07719.12 AIN99817.1 - 1.8 8.6 8.0 8 6.6 0.0 4.6 5 0 0 5 5 5 0 Tetratricopeptide repeat Nol1_Nop2_Fmu PF01189.12 AIN99818.1 - 1.6e-18 67.1 0.0 8.5e-09 35.1 0.0 2.9 2 1 0 2 2 2 2 NOL1/NOP2/sun family Methyltransf_26 PF13659.1 AIN99818.1 - 0.0046 16.9 0.1 0.015 15.3 0.1 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 AIN99818.1 - 0.016 15.7 0.1 0.19 12.3 0.0 2.4 2 0 0 2 2 2 0 Methyltransferase domain ATP-grasp PF02222.17 AIN99818.1 - 0.081 12.2 0.1 0.57 9.5 0.0 2.5 3 0 0 3 3 3 0 ATP-grasp domain Methyltransf_30 PF05430.6 AIN99819.1 - 0.033 13.8 0.0 0.066 12.8 0.0 1.4 1 0 0 1 1 1 0 S-adenosyl-L-methionine-dependent methyltransferase Pkinase PF00069.20 AIN99820.1 - 3e-16 59.3 0.0 5.9e-16 58.4 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain WD40 PF00400.27 AIN99820.1 - 1.2e-08 34.4 8.0 0.0006 19.6 0.3 4.9 4 0 0 4 4 4 3 WD domain, G-beta repeat Pkinase_Tyr PF07714.12 AIN99820.1 - 0.00056 19.0 0.0 0.001 18.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 AIN99820.1 - 0.079 11.9 0.0 0.14 11.0 0.0 1.3 1 0 0 1 1 1 0 Kinase-like RIO1 PF01163.17 AIN99820.1 - 0.21 10.9 0.0 0.68 9.2 0.0 1.7 2 0 0 2 2 2 0 RIO1 family Seadorna_VP7 PF07387.6 AIN99820.1 - 0.65 8.7 0.0 1.1 8.0 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Sporozoite_P67 PF05642.6 AIN99820.1 - 4.5 5.0 8.2 12 3.5 5.7 1.7 1 0 0 1 1 1 0 Sporozoite P67 surface antigen ArfGap PF01412.13 AIN99821.1 - 6.7e-12 45.2 0.0 1e-11 44.6 0.0 1.3 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf Topoisom_bac PF01131.15 AIN99822.1 - 1.1e-97 327.4 0.0 1.3e-97 327.1 0.0 1.1 1 0 0 1 1 1 1 DNA topoisomerase Toprim PF01751.17 AIN99822.1 - 9.6e-17 60.8 0.0 1.8e-16 59.9 0.0 1.5 1 0 0 1 1 1 1 Toprim domain AAA PF00004.24 AIN99823.1 - 6.6e-32 110.4 0.0 1e-31 109.9 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 AIN99823.1 - 1.6e-06 28.8 0.0 3.7e-06 27.7 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 AIN99823.1 - 1.7e-06 27.9 0.0 4.2e-06 26.6 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 AIN99823.1 - 3e-06 27.5 0.0 5.8e-06 26.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 AIN99823.1 - 5.5e-06 26.5 0.0 1.1e-05 25.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 AIN99823.1 - 2.4e-05 24.4 0.1 5.8e-05 23.1 0.1 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.9 AIN99823.1 - 0.00056 19.6 0.0 0.001 18.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) RNA_helicase PF00910.17 AIN99823.1 - 0.0013 18.8 0.0 0.003 17.7 0.0 1.6 1 0 0 1 1 1 1 RNA helicase AAA_28 PF13521.1 AIN99823.1 - 0.0019 18.1 0.0 0.0035 17.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 AIN99823.1 - 0.0023 17.6 0.0 0.01 15.5 0.0 2.1 1 0 0 1 1 1 1 Part of AAA domain RuvB_N PF05496.7 AIN99823.1 - 0.0037 16.3 0.0 0.0089 15.0 0.0 1.5 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus IstB_IS21 PF01695.12 AIN99823.1 - 0.0086 15.5 0.0 0.02 14.3 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_24 PF13479.1 AIN99823.1 - 0.0088 15.6 0.0 0.015 14.9 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_25 PF13481.1 AIN99823.1 - 0.0091 15.4 0.2 0.05 12.9 0.0 2.1 1 1 1 2 2 2 1 AAA domain UPF0079 PF02367.12 AIN99823.1 - 0.012 15.2 0.0 0.021 14.4 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 KTI12 PF08433.5 AIN99823.1 - 0.015 14.5 0.0 0.024 13.8 0.0 1.3 1 0 0 1 1 1 0 Chromatin associated protein KTI12 AAA_11 PF13086.1 AIN99823.1 - 0.015 14.8 0.0 0.023 14.2 0.0 1.2 1 0 0 1 1 1 0 AAA domain MobB PF03205.9 AIN99823.1 - 0.027 14.1 0.0 0.053 13.2 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B NACHT PF05729.7 AIN99823.1 - 0.031 13.9 0.0 0.064 12.9 0.0 1.5 1 0 0 1 1 1 0 NACHT domain AAA_30 PF13604.1 AIN99823.1 - 0.06 12.9 0.0 0.17 11.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain TIP49 PF06068.8 AIN99823.1 - 0.089 11.4 0.0 0.13 10.9 0.0 1.1 1 0 0 1 1 1 0 TIP49 C-terminus Mg_chelatase PF01078.16 AIN99823.1 - 0.09 11.9 0.0 0.26 10.4 0.0 1.7 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_14 PF13173.1 AIN99823.1 - 0.1 12.5 0.0 0.18 11.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain PduV-EutP PF10662.4 AIN99823.1 - 0.18 11.2 0.1 0.54 9.7 0.0 1.8 2 0 0 2 2 1 0 Ethanolamine utilisation - propanediol utilisation AAA_2 PF07724.9 AIN99823.1 - 0.19 11.6 0.0 1 9.2 0.0 2.0 1 1 0 1 1 1 0 AAA domain (Cdc48 subfamily) AAA_23 PF13476.1 AIN99823.1 - 0.25 11.6 0.0 0.4 10.9 0.0 1.2 1 0 0 1 1 1 0 AAA domain Rep_fac-A_C PF08646.5 AIN99826.1 - 2.3e-42 144.1 0.6 1.8e-40 137.9 0.1 2.9 3 0 0 3 3 3 1 Replication factor-A C terminal domain tRNA_anti-codon PF01336.20 AIN99826.1 - 2.6e-13 49.6 0.7 5.6e-10 38.9 0.0 2.9 3 1 0 3 3 3 2 OB-fold nucleic acid binding domain DZR PF12773.2 AIN99826.1 - 0.053 13.3 2.5 0.098 12.4 1.7 1.3 1 0 0 1 1 1 0 Double zinc ribbon SHS2_Rpb7-N PF03876.12 AIN99826.1 - 0.1 12.7 0.0 0.24 11.5 0.0 1.6 1 0 0 1 1 1 0 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 zinc-ribbons_6 PF07191.7 AIN99826.1 - 0.17 11.7 1.7 0.32 10.8 1.2 1.4 1 0 0 1 1 1 0 zinc-ribbons OrfB_Zn_ribbon PF07282.6 AIN99826.1 - 0.71 9.5 2.8 1.5 8.5 1.9 1.5 1 0 0 1 1 1 0 Putative transposase DNA-binding domain SNF2_N PF00176.18 AIN99827.1 - 1.7e-57 194.5 0.0 2.7e-57 193.8 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 AIN99827.1 - 1.7e-10 40.6 0.0 3.3e-10 39.6 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-RING_2 PF13639.1 AIN99827.1 - 1.1e-09 37.9 10.4 1.1e-09 37.9 7.2 2.5 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.1 AIN99827.1 - 1.8e-09 37.4 10.6 1.8e-09 37.4 7.3 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 AIN99827.1 - 4.8e-09 35.7 9.0 1.2e-08 34.4 6.3 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 AIN99827.1 - 2e-08 33.7 10.6 6.1e-08 32.2 7.3 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 AIN99827.1 - 5.6e-07 29.1 8.8 1.4e-06 27.8 6.1 1.8 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 AIN99827.1 - 0.00012 21.9 9.6 0.0003 20.6 6.6 1.8 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING ResIII PF04851.10 AIN99827.1 - 0.00044 20.1 0.0 0.0021 17.9 0.0 2.0 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit zf-RING_UBOX PF13445.1 AIN99827.1 - 0.00077 19.1 8.1 0.0018 17.9 5.6 1.7 1 0 0 1 1 1 1 RING-type zinc-finger Prok-RING_4 PF14447.1 AIN99827.1 - 0.05 13.1 3.8 0.13 11.8 2.7 1.7 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_6 PF14835.1 AIN99827.1 - 0.058 13.1 4.3 0.18 11.6 3.0 1.8 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-RING_4 PF14570.1 AIN99827.1 - 0.1 12.1 6.8 0.25 10.9 4.7 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-rbx1 PF12678.2 AIN99827.1 - 0.59 10.2 10.9 0.12 12.4 4.7 2.1 2 1 0 2 2 1 0 RING-H2 zinc finger zf-P11 PF03854.9 AIN99827.1 - 2.5 7.6 8.5 0.98 8.9 3.1 2.4 2 0 0 2 2 2 0 P-11 zinc finger Aldolase_II PF00596.16 AIN99828.1 - 5.2e-39 133.7 0.0 5.9e-39 133.5 0.0 1.0 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain Cytidylate_kin2 PF13189.1 AIN99828.1 - 0.086 12.7 0.0 0.21 11.4 0.0 1.6 1 0 0 1 1 1 0 Cytidylate kinase-like family Kinesin PF00225.18 AIN99829.1 - 4.3e-85 285.3 0.1 7.1e-85 284.6 0.1 1.3 1 0 0 1 1 1 1 Kinesin motor domain DUF904 PF06005.7 AIN99829.1 - 0.34 11.2 14.0 0.6 10.4 0.6 3.5 2 1 1 3 3 3 0 Protein of unknown function (DUF904) FAD-oxidase_C PF02913.14 AIN99829.1 - 1.1 8.4 6.7 0.29 10.4 2.1 1.9 2 0 0 2 2 2 0 FAD linked oxidases, C-terminal domain DUF4530 PF15039.1 AIN99829.1 - 2.7 7.9 11.1 6 6.8 1.3 3.2 2 1 0 2 2 2 0 Domain of unknown function (DUF4530) GAS PF13851.1 AIN99829.1 - 5.6 6.0 16.4 4.9 6.2 2.9 2.4 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding DUF4586 PF15239.1 AIN99830.1 - 2.6e-45 155.2 1.0 3.2e-45 154.9 0.7 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4586) Methyltransf_16 PF10294.4 AIN99831.1 - 1.4e-13 50.6 1.4 1.6e-11 44.0 0.2 3.3 2 1 0 2 2 2 1 Putative methyltransferase DUF663 PF04950.7 AIN99832.1 - 2.2e-72 243.5 0.0 3.5e-72 242.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF663) AARP2CN PF08142.7 AIN99832.1 - 4e-23 80.7 0.0 1.1e-22 79.3 0.0 1.8 1 0 0 1 1 1 1 AARP2CN (NUC121) domain AAA_22 PF13401.1 AIN99832.1 - 0.00011 22.3 0.0 0.00036 20.6 0.0 1.9 1 0 0 1 1 1 1 AAA domain MobB PF03205.9 AIN99832.1 - 0.00012 21.8 0.0 0.00029 20.5 0.0 1.7 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B GTP_EFTU PF00009.22 AIN99832.1 - 0.00015 21.2 0.0 0.0052 16.2 0.0 2.4 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain AAA_16 PF13191.1 AIN99832.1 - 0.0002 21.4 0.0 0.00058 19.8 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain AAA PF00004.24 AIN99832.1 - 0.0011 19.2 0.0 0.0029 17.7 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) MMR_HSR1 PF01926.18 AIN99832.1 - 0.0038 17.1 0.1 0.013 15.4 0.0 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_33 PF13671.1 AIN99832.1 - 0.0075 16.1 0.9 0.021 14.7 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 AIN99832.1 - 0.0096 16.7 0.0 0.0096 16.7 0.0 3.3 4 1 0 4 4 2 1 AAA domain ABC_tran PF00005.22 AIN99832.1 - 0.0097 16.2 0.1 0.044 14.0 0.0 2.1 2 0 0 2 2 1 1 ABC transporter AAA_5 PF07728.9 AIN99832.1 - 0.01 15.5 0.0 0.044 13.5 0.0 2.0 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) NACHT PF05729.7 AIN99832.1 - 0.01 15.4 0.0 0.022 14.4 0.0 1.6 1 0 0 1 1 1 0 NACHT domain cobW PF02492.14 AIN99832.1 - 0.012 15.0 0.0 0.09 12.2 0.0 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_10 PF12846.2 AIN99832.1 - 0.013 14.9 1.1 0.017 14.6 0.0 1.6 2 0 0 2 2 2 0 AAA-like domain NTPase_1 PF03266.10 AIN99832.1 - 0.015 14.9 0.0 0.033 13.9 0.0 1.6 1 0 0 1 1 1 0 NTPase ATP_bind_1 PF03029.12 AIN99832.1 - 0.017 14.6 0.0 0.036 13.6 0.0 1.5 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein Miro PF08477.8 AIN99832.1 - 0.02 15.4 0.0 0.062 13.8 0.0 1.9 2 0 0 2 2 1 0 Miro-like protein AAA_19 PF13245.1 AIN99832.1 - 0.022 14.4 0.1 0.065 13.0 0.1 1.7 1 0 0 1 1 1 0 Part of AAA domain AAA_18 PF13238.1 AIN99832.1 - 0.027 14.7 2.1 0.25 11.6 0.0 2.9 3 0 0 3 3 2 0 AAA domain AAA_24 PF13479.1 AIN99832.1 - 0.05 13.1 0.0 0.15 11.5 0.0 1.8 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.17 AIN99832.1 - 0.11 11.3 0.0 0.2 10.4 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain Arch_ATPase PF01637.13 AIN99832.1 - 0.29 10.8 0.0 0.29 10.8 0.0 2.4 3 0 0 3 3 3 0 Archaeal ATPase AAA_23 PF13476.1 AIN99832.1 - 0.45 10.8 6.5 4.9 7.4 0.0 3.3 3 0 0 3 3 3 0 AAA domain zf-DHHC PF01529.15 AIN99833.1 - 2.2e-25 89.0 1.9 2.2e-25 89.0 1.3 2.1 2 0 0 2 2 2 1 DHHC palmitoyltransferase DnaJ PF00226.26 AIN99834.1 - 1.3e-09 37.6 0.0 2.3e-09 36.8 0.0 1.4 1 0 0 1 1 1 1 DnaJ domain BCIP PF13862.1 AIN99835.1 - 1.8e-22 79.7 0.0 2.7e-22 79.2 0.0 1.2 1 0 0 1 1 1 1 p21-C-terminal region-binding protein dsDNA_bind PF01984.15 AIN99836.1 - 2.5e-22 78.8 12.0 2.8e-22 78.7 8.3 1.0 1 0 0 1 1 1 1 Double-stranded DNA-binding domain alpha-hel2 PF14456.1 AIN99836.1 - 0.6 8.8 3.5 0.65 8.7 2.4 1.0 1 0 0 1 1 1 0 Alpha-helical domain 2 UPF0154 PF03672.8 AIN99836.1 - 1.4 8.5 6.5 2.3 7.8 0.1 2.8 2 1 1 3 3 3 0 Uncharacterised protein family (UPF0154) LKAAEAR PF15478.1 AIN99836.1 - 2.5 8.3 9.2 3.1 8.0 5.1 1.8 1 1 1 2 2 2 0 Family of unknown function with LKAAEAR motif DUF2870 PF11069.3 AIN99836.1 - 6.5 6.8 7.8 4.5 7.3 3.5 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF2870) Zip PF02535.17 AIN99837.1 - 1.9e-38 132.2 10.3 1.9e-38 132.2 7.2 1.7 2 0 0 2 2 2 1 ZIP Zinc transporter 7TM_GPCR_Srx PF10328.4 AIN99837.1 - 0.11 11.6 1.4 0.15 11.1 0.4 1.6 2 0 0 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srx CorA PF01544.13 AIN99838.1 - 1.9e-08 33.6 2.7 7.3e-08 31.7 1.3 1.9 2 0 0 2 2 2 1 CorA-like Mg2+ transporter protein MAPEG PF01124.13 AIN99838.1 - 0.051 13.1 0.0 0.37 10.4 0.0 2.3 3 0 0 3 3 3 0 MAPEG family Peptidase_S15 PF02129.13 AIN99839.1 - 2e-56 191.4 0.3 5.4e-56 190.0 0.0 1.9 3 0 0 3 3 3 1 X-Pro dipeptidyl-peptidase (S15 family) PepX_C PF08530.5 AIN99839.1 - 2.7e-32 112.4 0.0 4.1e-32 111.8 0.0 1.2 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain Abhydrolase_6 PF12697.2 AIN99839.1 - 2.3e-13 50.5 0.5 4.9e-13 49.4 0.3 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 AIN99839.1 - 3.3e-11 43.1 0.1 7.7e-10 38.6 0.0 2.8 2 1 0 2 2 2 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 AIN99839.1 - 1.7e-06 27.3 0.9 3.9e-05 22.9 0.1 2.4 2 0 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_1 PF00561.15 AIN99839.1 - 0.00062 19.3 0.1 0.02 14.4 0.0 2.4 1 1 1 2 2 2 1 alpha/beta hydrolase fold DLH PF01738.13 AIN99839.1 - 0.072 12.3 0.0 0.15 11.2 0.0 1.5 1 0 0 1 1 1 0 Dienelactone hydrolase family GTP_EFTU PF00009.22 AIN99840.1 - 6.4e-39 133.3 0.0 1.1e-38 132.5 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_II PF14492.1 AIN99840.1 - 2.9e-19 68.6 0.0 5.6e-19 67.7 0.0 1.5 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_C PF00679.19 AIN99840.1 - 1.9e-12 46.9 0.0 4.7e-12 45.5 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 AIN99840.1 - 1e-06 28.7 0.0 3e-06 27.2 0.0 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 AIN99840.1 - 0.0075 16.2 0.0 0.017 15.0 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase AIG1 PF04548.11 AIN99840.1 - 0.0097 15.0 0.0 0.018 14.1 0.0 1.3 1 0 0 1 1 1 1 AIG1 family SRPRB PF09439.5 AIN99840.1 - 0.025 13.7 0.0 0.048 12.8 0.0 1.4 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit FeoB_N PF02421.13 AIN99840.1 - 0.051 12.8 0.0 0.17 11.1 0.0 1.8 1 1 0 1 1 1 0 Ferrous iron transport protein B Miro PF08477.8 AIN99840.1 - 0.075 13.5 0.0 0.15 12.5 0.0 1.5 1 0 0 1 1 1 0 Miro-like protein LacAB_rpiB PF02502.13 AIN99841.1 - 2.4e-51 173.0 0.7 2.7e-51 172.8 0.5 1.0 1 0 0 1 1 1 1 Ribose/Galactose Isomerase LRR_6 PF13516.1 AIN99843.1 - 1.3e-19 67.9 1.1 0.084 12.9 0.0 8.1 8 0 0 8 8 8 4 Leucine Rich repeat LRR_4 PF12799.2 AIN99843.1 - 1.5e-08 34.0 8.7 0.012 15.2 0.3 5.5 2 1 5 7 7 7 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 AIN99843.1 - 1.1e-07 30.9 3.0 0.81 9.9 0.0 7.1 7 1 1 8 8 8 1 Leucine Rich Repeat LRR_8 PF13855.1 AIN99843.1 - 0.0062 16.2 12.7 0.05 13.3 0.7 4.6 1 1 3 5 5 5 3 Leucine rich repeat PspA_IM30 PF04012.7 AIN99843.1 - 0.01 15.2 0.6 0.047 13.0 0.4 2.2 1 0 0 1 1 1 0 PspA/IM30 family DivIC PF04977.10 AIN99843.1 - 0.047 13.1 1.6 0.15 11.5 1.1 1.8 1 0 0 1 1 1 0 Septum formation initiator Spectrin PF00435.16 AIN99843.1 - 0.065 13.5 0.6 0.17 12.2 0.4 1.6 1 0 0 1 1 1 0 Spectrin repeat LRR_7 PF13504.1 AIN99843.1 - 0.2 11.9 13.5 3.4 8.2 0.0 6.4 7 0 0 7 7 7 0 Leucine rich repeat DUF4407 PF14362.1 AIN99843.1 - 0.33 9.8 3.0 0.7 8.7 2.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF2244 PF10003.4 AIN99844.1 - 0.024 13.9 2.2 0.029 13.7 1.6 1.1 1 0 0 1 1 1 0 Integral membrane protein (DUF2244) DuoxA PF10204.4 AIN99844.1 - 0.17 10.9 3.7 0.18 10.8 2.5 1.0 1 0 0 1 1 1 0 Dual oxidase maturation factor DUF4131 PF13567.1 AIN99844.1 - 0.48 9.7 4.6 0.54 9.6 3.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) Anophelin PF10731.4 AIN99844.1 - 0.76 9.9 2.9 1.5 8.9 2.0 1.4 1 0 0 1 1 1 0 Thrombin inhibitor from mosquito DUF4282 PF14110.1 AIN99844.1 - 2.9 8.1 8.6 4.8 7.4 5.9 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4282) Pkinase PF00069.20 AIN99845.1 - 1.4e-45 155.4 0.0 7e-45 153.1 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AIN99845.1 - 1.9e-21 76.3 0.0 2.8e-21 75.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 AIN99845.1 - 0.0012 17.8 0.0 0.002 17.1 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 AIN99845.1 - 0.025 14.3 0.0 0.053 13.2 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family Choline_kinase PF01633.15 AIN99845.1 - 0.043 13.3 0.0 0.076 12.5 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase Pox_ser-thr_kin PF05445.6 AIN99845.1 - 0.08 11.7 0.0 0.12 11.1 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Kdo PF06293.9 AIN99845.1 - 0.13 11.3 0.0 0.22 10.5 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Sporozoite_P67 PF05642.6 AIN99845.1 - 0.2 9.4 4.4 0.37 8.5 3.1 1.4 1 0 0 1 1 1 0 Sporozoite P67 surface antigen TRAP_alpha PF03896.11 AIN99845.1 - 2.4 7.0 4.9 3 6.7 2.5 1.8 2 0 0 2 2 2 0 Translocon-associated protein (TRAP), alpha subunit D123 PF07065.9 AIN99846.1 - 0.053 12.5 0.0 0.69 8.9 0.0 2.4 3 0 0 3 3 3 0 D123 DUF2783 PF10932.3 AIN99847.1 - 0.063 12.7 0.0 0.17 11.3 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2783) GRIM-19 PF06212.7 AIN99848.1 - 1.8e-09 37.4 0.0 2.2e-09 37.1 0.0 1.1 1 0 0 1 1 1 1 GRIM-19 protein DPCD PF14913.1 AIN99849.1 - 3.3e-53 179.7 0.0 3.7e-53 179.5 0.0 1.0 1 0 0 1 1 1 1 DPCD protein family TilS_C PF11734.3 AIN99849.1 - 0.057 12.6 0.0 0.11 11.7 0.0 1.4 1 0 0 1 1 1 0 TilS substrate C-terminal domain AMP-binding PF00501.23 AIN99850.1 - 5e-31 107.5 0.0 1.1e-30 106.4 0.0 1.5 1 0 0 1 1 1 1 AMP-binding enzyme Ank_2 PF12796.2 AIN99850.1 - 1.9e-18 66.5 1.2 2.6e-11 43.7 0.0 2.5 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 AIN99850.1 - 9.2e-15 53.6 1.6 0.00025 20.6 0.0 4.7 4 0 0 4 4 4 3 Ankyrin repeat Ank_4 PF13637.1 AIN99850.1 - 1.1e-14 54.4 0.2 5.9e-10 39.3 0.0 3.2 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_5 PF13857.1 AIN99850.1 - 3.7e-11 42.8 6.8 2.6e-08 33.8 0.1 4.5 2 1 3 5 5 5 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 AIN99850.1 - 3.1e-10 39.2 0.9 0.055 13.7 0.0 5.0 4 0 0 4 4 4 3 Ankyrin repeat AMP-binding_C PF13193.1 AIN99850.1 - 6.6e-05 23.7 0.0 0.00019 22.3 0.0 1.9 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain PP-binding PF00550.20 AIN99850.1 - 0.031 14.5 0.0 0.075 13.3 0.0 1.7 1 0 0 1 1 1 0 Phosphopantetheine attachment site GH3 PF03321.8 AIN99850.1 - 0.18 10.2 0.0 0.86 8.0 0.0 1.9 2 0 0 2 2 2 0 GH3 auxin-responsive promoter RNA_pol_L_2 PF13656.1 AIN99851.1 - 2e-22 78.4 0.0 2.9e-22 77.9 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.19 AIN99851.1 - 0.00024 20.1 0.0 0.00043 19.3 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Sua5_yciO_yrdC PF01300.13 AIN99852.1 - 5.9e-47 159.2 0.0 8.4e-47 158.7 0.0 1.2 1 0 0 1 1 1 1 Telomere recombination SUA5 PF03481.8 AIN99852.1 - 1.3e-08 34.9 0.0 2.3e-08 34.1 0.0 1.4 1 0 0 1 1 1 1 Putative GTP-binding controlling metal-binding Helicase_C PF00271.26 AIN99853.1 - 4.6e-25 87.2 0.2 9.6e-25 86.2 0.1 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 AIN99853.1 - 0.004 16.6 0.0 0.1 12.1 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase CEP76-C2 PF15627.1 AIN99854.1 - 9.1e-41 138.9 0.0 1.4e-40 138.3 0.0 1.3 1 0 0 1 1 1 1 CEP76 C2 domain C2 PF00168.25 AIN99854.1 - 0.13 12.0 0.0 0.35 10.7 0.0 1.7 1 0 0 1 1 1 0 C2 domain UPF0220 PF05255.6 AIN99855.1 - 3.3e-16 58.9 1.8 3.6e-16 58.8 1.2 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0220) DUF4010 PF13194.1 AIN99855.1 - 0.011 15.0 0.6 0.013 14.8 0.2 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4010) DUF4131 PF13567.1 AIN99855.1 - 0.079 12.3 0.0 0.079 12.3 0.0 2.3 1 1 2 3 3 3 0 Domain of unknown function (DUF4131) DUF1469 PF07332.6 AIN99855.1 - 1.1 8.9 7.5 4.5 7.0 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1469) YjgP_YjgQ PF03739.9 AIN99855.1 - 2 7.0 10.5 0.56 8.8 2.3 2.0 2 0 0 2 2 2 0 Predicted permease YjgP/YjgQ family DUF3784 PF12650.2 AIN99855.1 - 2.7 8.0 5.2 2 8.4 0.5 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF3784) GDPD PF03009.12 AIN99856.1 - 2.7e-19 69.6 0.0 4.5e-16 59.1 0.0 2.1 2 0 0 2 2 2 2 Glycerophosphoryl diester phosphodiesterase family Cullin PF00888.17 AIN99857.1 - 3.3e-40 138.2 2.8 4.7e-40 137.7 2.0 1.2 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.4 AIN99857.1 - 7.6e-13 48.0 0.0 4.2e-12 45.7 0.0 2.3 2 0 0 2 2 2 1 Cullin protein neddylation domain TrmB PF01978.14 AIN99857.1 - 0.0068 16.0 1.1 0.044 13.4 0.1 2.5 2 0 0 2 2 2 1 Sugar-specific transcriptional regulator TrmB Penicillinase_R PF03965.11 AIN99857.1 - 0.015 15.4 0.1 0.091 12.8 0.0 2.4 2 0 0 2 2 2 0 Penicillinase repressor Cullin PF00888.17 AIN99858.1 - 1.6e-32 112.8 0.0 2.2e-32 112.3 0.0 1.1 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.4 AIN99858.1 - 8e-06 25.5 0.3 2.7e-05 23.8 0.0 2.1 3 0 0 3 3 3 1 Cullin protein neddylation domain Penicillinase_R PF03965.11 AIN99858.1 - 0.00023 21.2 0.2 0.00092 19.2 0.0 2.2 2 0 0 2 2 2 1 Penicillinase repressor HTH_27 PF13463.1 AIN99858.1 - 0.00032 20.9 0.1 0.041 14.1 0.1 2.7 2 0 0 2 2 2 1 Winged helix DNA-binding domain HTH_20 PF12840.2 AIN99858.1 - 0.022 14.5 0.1 9.2 6.1 0.1 3.0 3 0 0 3 3 3 0 Helix-turn-helix domain Dynein_light PF01221.13 AIN99859.1 - 6e-32 109.5 0.0 6.7e-32 109.3 0.0 1.0 1 0 0 1 1 1 1 Dynein light chain type 1 Ground-like PF04155.13 AIN99859.1 - 0.032 14.5 0.0 0.042 14.1 0.0 1.3 1 1 0 1 1 1 0 Ground-like domain HhH-GPD PF00730.20 AIN99860.1 - 3.7e-16 59.3 0.0 4.7e-15 55.7 0.0 2.5 2 1 1 3 3 3 1 HhH-GPD superfamily base excision DNA repair protein NUDIX_4 PF14815.1 AIN99860.1 - 7.8e-13 47.8 0.0 2.1e-12 46.4 0.0 1.6 1 0 0 1 1 1 1 NUDIX domain HHH PF00633.18 AIN99860.1 - 1.1e-05 24.7 0.2 4.3e-05 22.9 0.0 2.1 2 0 0 2 2 2 1 Helix-hairpin-helix motif HHH_5 PF14520.1 AIN99860.1 - 0.076 13.2 0.0 2.8 8.1 0.0 2.4 2 0 0 2 2 2 0 Helix-hairpin-helix domain HHH_2 PF12826.2 AIN99860.1 - 0.18 11.7 0.0 7.7 6.4 0.0 2.4 2 0 0 2 2 2 0 Helix-hairpin-helix motif Kelch_3 PF13415.1 AIN99861.1 - 2.4e-10 40.2 0.7 0.00015 21.8 0.0 3.8 3 1 0 3 3 3 2 Galactose oxidase, central domain Kelch_4 PF13418.1 AIN99861.1 - 7.5e-10 38.4 0.1 7.9e-07 28.7 0.0 4.2 4 0 0 4 4 4 1 Galactose oxidase, central domain Kelch_6 PF13964.1 AIN99861.1 - 7e-08 32.3 0.0 0.0019 18.2 0.0 3.9 3 0 0 3 3 3 2 Kelch motif Kelch_5 PF13854.1 AIN99861.1 - 1.2e-05 25.1 0.0 0.00043 20.1 0.0 3.5 2 0 0 2 2 2 1 Kelch motif Kelch_2 PF07646.10 AIN99861.1 - 0.00022 20.8 0.0 0.00022 20.8 0.0 3.4 4 0 0 4 4 4 1 Kelch motif APS-reductase_C PF12139.3 AIN99861.1 - 0.004 17.2 0.0 0.0086 16.2 0.0 1.5 1 0 0 1 1 1 1 Adenosine-5'-phosphosulfate reductase beta subunit Methyltransf_18 PF12847.2 AIN99862.1 - 8.1e-07 29.6 0.0 1.4e-06 28.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 AIN99862.1 - 8.2e-07 29.4 0.0 1.8e-06 28.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 AIN99862.1 - 1.5e-05 24.6 0.0 1.9e-05 24.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 AIN99862.1 - 0.0001 22.6 0.0 0.00017 21.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain UPF0020 PF01170.13 AIN99862.1 - 0.033 13.7 0.0 0.049 13.1 0.0 1.3 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 TBPIP PF07106.8 AIN99863.1 - 0.052 13.0 3.5 0.13 11.8 2.4 1.7 1 0 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Sel1 PF08238.7 AIN99863.1 - 0.073 13.7 7.5 0.43 11.2 0.1 3.6 4 0 0 4 4 4 0 Sel1 repeat bZIP_1 PF00170.16 AIN99865.1 - 0.034 14.1 5.4 2.3 8.2 0.7 3.1 2 0 0 2 2 2 0 bZIP transcription factor SAP30_Sin3_bdg PF13867.1 AIN99865.1 - 0.09 12.6 0.2 0.23 11.3 0.1 1.7 1 0 0 1 1 1 0 Sin3 binding region of histone deacetylase complex subunit SAP30 Glyco_hydro_63 PF03200.11 AIN99866.1 - 9.6e-61 205.6 0.1 8.4e-58 195.9 0.1 2.2 1 1 0 1 1 1 1 Mannosyl oligosaccharide glucosidase Ribosomal_S14 PF00253.16 AIN99867.1 - 2.3e-16 58.9 3.4 2.4e-16 58.8 2.3 1.0 1 0 0 1 1 1 1 Ribosomal protein S14p/S29e Ribosomal_L40e PF01020.12 AIN99867.1 - 0.052 13.1 2.2 0.42 10.2 0.5 2.2 2 0 0 2 2 2 0 Ribosomal L40e family PhosphMutase PF10143.4 AIN99869.1 - 5.8e-57 192.0 0.0 1.1e-56 191.1 0.0 1.5 1 0 0 1 1 1 1 2,3-bisphosphoglycerate-independent phosphoglycerate mutase Metalloenzyme PF01676.13 AIN99869.1 - 3.7e-18 65.8 0.0 7.8e-17 61.4 0.0 2.3 2 1 0 2 2 2 1 Metalloenzyme superfamily AIG2 PF06094.7 AIN99869.1 - 1.4e-10 41.5 0.0 5.7e-10 39.6 0.0 2.2 1 1 0 1 1 1 1 AIG2-like family Cyclin_N PF00134.18 AIN99870.1 - 0.00047 19.7 0.1 0.00099 18.6 0.1 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain Type_III_YscX PF09474.5 AIN99870.1 - 0.15 12.0 0.0 1.4 8.9 0.0 2.2 2 0 0 2 2 2 0 Type III secretion system YscX (type_III_YscX) PEX11 PF05648.9 AIN99872.1 - 2.1e-05 23.9 1.0 2.9e-05 23.4 0.7 1.4 1 1 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) PEX11 PF05648.9 AIN99873.1 - 1.6e-23 83.1 0.6 2.2e-23 82.6 0.4 1.2 1 0 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) MOZ_SAS PF01853.13 AIN99874.1 - 3.8e-37 127.3 0.3 3.1e-20 72.2 0.4 2.7 3 0 0 3 3 3 2 MOZ/SAS family DNA_topoisoIV PF00521.15 AIN99875.1 - 2.5e-129 431.8 0.0 4.8e-129 430.9 0.0 1.5 1 0 0 1 1 1 1 DNA gyrase/topoisomerase IV, subunit A DNA_gyraseB PF00204.20 AIN99875.1 - 9e-29 99.8 0.1 2.1e-28 98.7 0.1 1.5 1 0 0 1 1 1 1 DNA gyrase B HATPase_c PF02518.21 AIN99875.1 - 1.4e-09 37.6 0.0 5e-09 35.8 0.0 1.9 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Toprim PF01751.17 AIN99875.1 - 1.5e-08 34.4 0.0 3.9e-08 33.1 0.0 1.7 1 0 0 1 1 1 1 Toprim domain DNA_gyraseB_C PF00986.16 AIN99875.1 - 0.046 13.4 0.0 0.14 11.9 0.0 1.9 1 0 0 1 1 1 0 DNA gyrase B subunit, carboxyl terminus Hexapep PF00132.19 AIN99876.1 - 7e-08 31.6 1.6 0.0004 19.7 0.1 3.9 1 1 3 4 4 4 4 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.2 AIN99876.1 - 0.012 15.6 0.2 0.037 14.1 0.1 1.9 1 1 0 1 1 1 0 MobA-like NTP transferase domain NTP_transferase PF00483.18 AIN99876.1 - 0.019 14.2 0.0 0.14 11.4 0.0 2.0 2 0 0 2 2 2 0 Nucleotidyl transferase Hexapep_2 PF14602.1 AIN99876.1 - 0.026 14.0 4.0 0.93 9.1 0.4 3.5 1 1 1 2 2 2 0 Hexapeptide repeat of succinyl-transferase zf-SNAP50_C PF12251.3 AIN99877.1 - 0.059 12.7 0.1 0.11 11.8 0.1 1.4 1 0 0 1 1 1 0 snRNA-activating protein of 50kDa MW C terminal Cep57_MT_bd PF06657.8 AIN99877.1 - 0.069 13.0 0.0 0.069 13.0 0.0 3.2 3 1 0 3 3 3 0 Centrosome microtubule-binding domain of Cep57 UPF0184 PF03670.8 AIN99877.1 - 0.43 10.7 6.4 0.43 10.7 1.3 2.5 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0184) eIF3_N PF09440.5 AIN99878.1 - 2.3e-26 92.5 0.7 4.8e-26 91.5 0.5 1.5 1 0 0 1 1 1 1 eIF3 subunit 6 N terminal domain PCI PF01399.22 AIN99878.1 - 2.1e-10 40.8 1.0 5.4e-10 39.5 0.7 1.7 1 0 0 1 1 1 1 PCI domain CactinC_cactus PF09732.4 AIN99880.1 - 1.7e-39 134.2 1.7 3e-39 133.4 1.2 1.3 1 0 0 1 1 1 1 Cactus-binding C-terminus of cactin protein SHMT PF00464.14 AIN99883.1 - 1.3e-178 593.4 0.0 1.6e-178 593.1 0.0 1.1 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Aminotran_5 PF00266.14 AIN99883.1 - 0.00014 20.7 0.0 0.00025 19.9 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.16 AIN99883.1 - 0.0011 18.2 0.0 0.0025 16.9 0.0 1.7 1 1 0 1 1 1 1 Beta-eliminating lyase CBP PF12192.3 AIN99883.1 - 0.076 12.9 0.1 0.17 11.8 0.1 1.5 1 0 0 1 1 1 0 Fungal calcium binding protein Lectin_N PF03954.9 AIN99884.1 - 0.2 11.0 0.7 8.6 5.7 0.0 2.9 3 0 0 3 3 3 0 Hepatic lectin, N-terminal domain MCM PF00493.18 AIN99885.1 - 1.3e-120 402.2 0.3 1.8e-120 401.6 0.2 1.2 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 AIN99885.1 - 5.4e-08 33.3 0.0 1.3e-07 32.1 0.0 1.6 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.16 AIN99885.1 - 5.6e-07 28.9 0.0 3.7e-06 26.2 0.0 2.2 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 AIN99885.1 - 0.00059 19.5 0.1 0.0032 17.1 0.0 2.2 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.21 AIN99885.1 - 0.0078 15.6 0.1 0.021 14.2 0.1 1.7 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_3 PF07726.6 AIN99885.1 - 0.0087 15.6 0.0 0.022 14.3 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) WW PF00397.21 AIN99886.1 - 1.7e-09 37.3 0.7 3.9e-09 36.1 0.5 1.7 1 0 0 1 1 1 1 WW domain GCD14 PF08704.5 AIN99887.1 - 4.2e-64 216.3 0.6 3.9e-38 131.3 0.0 3.0 1 1 2 3 3 3 2 tRNA methyltransferase complex GCD14 subunit Methyltransf_31 PF13847.1 AIN99887.1 - 4.3e-11 42.6 0.0 8.6e-11 41.6 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 AIN99887.1 - 1.7e-06 27.7 0.0 4.5e-06 26.3 0.0 1.7 1 1 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_26 PF13659.1 AIN99887.1 - 3.9e-06 26.8 0.4 1.2e-05 25.2 0.3 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 AIN99887.1 - 4.2e-05 23.9 0.0 0.00011 22.5 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Fibrillarin PF01269.12 AIN99887.1 - 0.00035 19.5 0.0 0.087 11.7 0.0 2.2 2 0 0 2 2 2 2 Fibrillarin MTS PF05175.9 AIN99887.1 - 0.00069 19.0 0.0 0.0021 17.4 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_18 PF12847.2 AIN99887.1 - 0.00087 19.8 0.0 0.0018 18.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_24 PF13578.1 AIN99887.1 - 0.0016 19.2 0.3 0.0042 17.9 0.0 1.8 2 0 0 2 2 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 AIN99887.1 - 0.0037 16.3 0.0 0.033 13.3 0.0 2.0 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.7 AIN99887.1 - 0.0056 17.1 0.0 0.06 13.8 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain RrnaAD PF00398.15 AIN99887.1 - 0.0063 15.5 0.0 0.01 14.8 0.0 1.3 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase PrmA PF06325.8 AIN99887.1 - 0.025 13.7 0.0 0.045 12.8 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_25 PF13649.1 AIN99887.1 - 0.075 13.3 0.5 0.36 11.2 0.1 2.4 2 1 0 2 2 2 0 Methyltransferase domain Methyltransf_23 PF13489.1 AIN99887.1 - 0.077 12.7 0.0 0.14 11.8 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase domain CMAS PF02353.15 AIN99887.1 - 0.092 11.8 0.0 0.18 10.8 0.0 1.4 2 0 0 2 2 2 0 Mycolic acid cyclopropane synthetase Methyltransf_3 PF01596.12 AIN99887.1 - 0.11 11.5 0.0 0.18 10.8 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase Rft-1 PF04506.8 AIN99888.1 - 1.5e-24 86.3 9.4 3e-22 78.7 1.8 2.5 3 0 0 3 3 3 2 Rft protein 2-oxoacid_dh PF00198.18 AIN99889.1 - 2e-80 269.4 0.6 2.5e-80 269.0 0.4 1.1 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.17 AIN99889.1 - 5.2e-20 70.8 1.2 8.9e-20 70.1 0.8 1.4 1 0 0 1 1 1 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.1 AIN99889.1 - 3.3e-05 23.4 0.3 0.14 11.8 0.0 2.4 1 1 1 2 2 2 2 Biotin-lipoyl like GCV_H PF01597.14 AIN99889.1 - 0.00055 19.6 0.6 0.0011 18.6 0.4 1.5 1 0 0 1 1 1 1 Glycine cleavage H-protein HlyD PF00529.15 AIN99889.1 - 0.0049 16.2 2.1 0.012 14.9 0.5 2.0 2 0 0 2 2 2 1 HlyD family secretion protein HlyD_3 PF13437.1 AIN99889.1 - 0.0099 16.2 0.3 0.54 10.6 0.0 2.4 1 1 1 2 2 2 1 HlyD family secretion protein HlyD_2 PF12700.2 AIN99889.1 - 0.01 15.0 0.1 1.1 8.3 0.0 2.3 1 1 1 2 2 2 0 HlyD family secretion protein ATP-synt_ab PF00006.20 AIN99890.1 - 1.9e-62 210.5 0.0 2.4e-62 210.2 0.0 1.1 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 AIN99890.1 - 1.7e-14 54.2 0.0 3.4e-14 53.2 0.0 1.5 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 AIN99890.1 - 1.1e-12 48.0 0.7 2.1e-12 47.0 0.5 1.5 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain NTP_transferase PF00483.18 AIN99891.1 - 1.8e-05 24.2 0.0 8.9e-05 21.9 0.0 2.0 3 0 0 3 3 3 1 Nucleotidyl transferase NTP_transf_3 PF12804.2 AIN99891.1 - 0.0078 16.3 0.1 0.096 12.7 0.0 2.6 2 1 0 2 2 2 1 MobA-like NTP transferase domain Hexapep PF00132.19 AIN99891.1 - 0.01 15.3 10.0 0.21 11.1 0.2 3.5 1 1 3 4 4 4 0 Bacterial transferase hexapeptide (six repeats) SLT_beta PF02258.11 AIN99891.1 - 0.075 12.8 0.0 0.2 11.5 0.0 1.7 1 0 0 1 1 1 0 Shiga-like toxin beta subunit HTH_DeoR PF08220.7 AIN99891.1 - 0.12 11.9 0.0 0.38 10.3 0.0 1.9 1 0 0 1 1 1 0 DeoR-like helix-turn-helix domain DUF676 PF05057.9 AIN99892.1 - 2.8e-11 43.1 0.1 1.3e-10 40.9 0.0 1.9 1 1 0 1 1 1 1 Putative serine esterase (DUF676) Ribosomal_S14 PF00253.16 AIN99893.1 - 2.3e-16 58.9 3.4 2.4e-16 58.8 2.3 1.0 1 0 0 1 1 1 1 Ribosomal protein S14p/S29e Ribosomal_L40e PF01020.12 AIN99893.1 - 0.052 13.1 2.2 0.42 10.2 0.5 2.2 2 0 0 2 2 2 0 Ribosomal L40e family ParA PF10609.4 AIN99894.1 - 8.4e-35 118.5 0.0 1.5e-34 117.7 0.0 1.4 1 0 0 1 1 1 1 ParA/MinD ATPase like CbiA PF01656.18 AIN99894.1 - 7e-19 67.9 0.0 9.9e-19 67.5 0.0 1.2 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain MipZ PF09140.6 AIN99894.1 - 5e-08 32.3 1.2 3.2e-07 29.6 0.8 1.9 1 1 0 1 1 1 1 ATPase MipZ AAA_31 PF13614.1 AIN99894.1 - 3.6e-07 30.2 0.0 1.1e-06 28.6 0.0 1.8 1 1 0 1 1 1 1 AAA domain VirC1 PF07015.6 AIN99894.1 - 2.9e-05 23.2 0.1 5.7e-05 22.3 0.0 1.4 1 0 0 1 1 1 1 VirC1 protein ArsA_ATPase PF02374.10 AIN99894.1 - 0.00025 20.2 0.3 0.0017 17.5 0.3 2.0 2 0 0 2 2 2 1 Anion-transporting ATPase Fer4_NifH PF00142.13 AIN99894.1 - 0.0003 20.0 0.0 0.0014 17.8 0.1 1.9 2 0 0 2 2 2 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family MobB PF03205.9 AIN99894.1 - 0.019 14.7 0.2 0.048 13.3 0.1 1.7 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B DUF1611 PF07755.6 AIN99894.1 - 0.35 9.4 1.4 0.44 9.1 0.2 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1611) PsiE PF06146.7 AIN99895.1 - 0.11 12.7 1.2 0.17 12.1 0.0 1.9 2 0 0 2 2 2 0 Phosphate-starvation-inducible E IF4E PF01652.13 AIN99897.1 - 2.4e-30 105.2 0.0 3.3e-30 104.7 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E MRP-L20 PF12824.2 AIN99897.1 - 0.0028 17.6 0.4 0.0055 16.6 0.3 1.4 1 0 0 1 1 1 1 Mitochondrial ribosomal protein subunit L20 PAM2 PF07145.10 AIN99897.1 - 0.013 14.9 1.0 1.6 8.3 0.0 2.7 2 0 0 2 2 2 0 Ataxin-2 C-terminal region Acyl-CoA_dh_C PF12806.2 AIN99898.1 - 7.2e-26 90.5 1.7 1.7e-25 89.3 1.1 1.6 1 0 0 1 1 1 1 Acetyl-CoA dehydrogenase C-terminal like Acyl-CoA_dh_1 PF00441.19 AIN99898.1 - 3.2e-18 66.2 4.4 4.4e-17 62.5 3.0 2.4 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 AIN99898.1 - 1.9e-14 52.8 0.0 4.5e-14 51.7 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.11 AIN99898.1 - 1.2e-11 45.1 0.1 2.7e-11 44.0 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.6 AIN99898.1 - 2.8e-07 30.8 0.3 6.6e-07 29.6 0.2 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain R3H PF01424.17 AIN99899.1 - 2.9e-10 39.6 0.4 8.5e-10 38.1 0.3 1.9 1 0 0 1 1 1 1 R3H domain PIF1 PF05970.9 AIN99900.1 - 3.3e-30 105.2 0.1 5.3e-25 88.1 0.0 3.9 4 0 0 4 4 4 2 PIF1-like helicase AAA_30 PF13604.1 AIN99900.1 - 1.9e-11 43.9 0.8 3.7e-11 42.9 0.0 1.9 2 0 0 2 2 1 1 AAA domain UvrD_C_2 PF13538.1 AIN99900.1 - 2.3e-05 24.4 0.0 5.7e-05 23.2 0.0 1.8 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain Viral_helicase1 PF01443.13 AIN99900.1 - 4.4e-05 23.1 0.0 0.33 10.4 0.0 3.0 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase AAA_19 PF13245.1 AIN99900.1 - 0.00074 19.2 0.2 0.0028 17.3 0.2 2.0 1 0 0 1 1 1 1 Part of AAA domain MobB PF03205.9 AIN99900.1 - 0.0026 17.4 0.0 0.0058 16.3 0.0 1.5 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B DUF2075 PF09848.4 AIN99900.1 - 0.013 14.4 0.3 0.041 12.8 0.2 1.9 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) DUF853 PF05872.7 AIN99900.1 - 0.016 13.6 0.2 0.016 13.6 0.1 1.9 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF853) AAA PF00004.24 AIN99900.1 - 0.038 14.1 0.0 0.12 12.6 0.0 1.8 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.16 AIN99900.1 - 0.039 13.0 0.0 0.09 11.9 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI T2SE PF00437.15 AIN99900.1 - 0.041 12.7 0.0 0.24 10.2 0.0 2.1 2 0 0 2 2 2 0 Type II/IV secretion system protein PhoH PF02562.11 AIN99900.1 - 0.086 12.0 0.0 0.17 11.0 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein AAA_22 PF13401.1 AIN99900.1 - 0.094 12.8 0.6 0.73 9.9 0.4 2.4 1 1 0 1 1 1 0 AAA domain NTPase_1 PF03266.10 AIN99900.1 - 0.1 12.3 1.3 0.38 10.4 0.2 2.3 2 0 0 2 2 2 0 NTPase Pox_A32 PF04665.7 AIN99900.1 - 0.1 11.8 0.1 0.17 11.1 0.1 1.2 1 0 0 1 1 1 0 Poxvirus A32 protein AAA_10 PF12846.2 AIN99900.1 - 0.17 11.2 0.0 0.61 9.4 0.0 1.9 2 0 0 2 2 2 0 AAA-like domain UvrD-helicase PF00580.16 AIN99900.1 - 0.2 10.9 0.0 0.36 10.0 0.0 1.4 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain cobW PF02492.14 AIN99900.1 - 0.23 10.8 0.3 1.1 8.7 0.2 2.0 1 1 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain HEAT_2 PF13646.1 AIN99901.1 - 6.3e-12 45.6 16.6 6.5e-06 26.3 0.2 6.3 6 1 0 6 6 6 3 HEAT repeats HEAT PF02985.17 AIN99901.1 - 4e-06 26.4 10.7 0.0036 17.2 0.0 5.8 6 0 0 6 6 6 3 HEAT repeat TPR_2 PF07719.12 AIN99902.1 - 0.00093 18.9 0.2 0.32 11.0 0.0 2.9 2 0 0 2 2 2 2 Tetratricopeptide repeat zf-MYND PF01753.13 AIN99902.1 - 0.005 16.6 8.1 0.005 16.6 5.6 2.5 2 0 0 2 2 2 1 MYND finger TPR_11 PF13414.1 AIN99902.1 - 0.025 14.2 0.1 0.13 11.9 0.0 2.2 1 1 1 2 2 2 0 TPR repeat SET PF00856.23 AIN99902.1 - 0.041 14.1 0.0 0.11 12.8 0.0 1.7 1 0 0 1 1 1 0 SET domain Zn-ribbon_8 PF09723.5 AIN99902.1 - 0.045 13.7 0.3 0.16 11.9 0.2 2.0 1 0 0 1 1 1 0 Zinc ribbon domain Ribosomal_S17e PF00833.13 AIN99903.1 - 1.4e-50 170.1 3.3 1.8e-50 169.7 2.3 1.1 1 0 0 1 1 1 1 Ribosomal S17 Ribosomal_S17e PF00833.13 AIN99904.1 - 1.4e-50 170.1 3.3 1.8e-50 169.7 2.3 1.1 1 0 0 1 1 1 1 Ribosomal S17 HEAT_2 PF13646.1 AIN99906.1 - 2.9e-12 46.6 18.9 0.0022 18.2 2.5 7.1 4 2 3 7 7 7 4 HEAT repeats SF3b1 PF08920.5 AIN99906.1 - 7.4e-07 29.2 0.0 1.4e-06 28.3 0.0 1.3 1 0 0 1 1 1 1 Splicing factor 3B subunit 1 UME PF08064.8 AIN99906.1 - 7.2e-05 22.6 1.8 0.032 14.1 0.0 4.3 4 1 0 4 4 4 1 UME (NUC010) domain HEAT_EZ PF13513.1 AIN99906.1 - 0.0012 19.2 19.4 6.6 7.3 0.1 8.0 7 2 2 9 9 9 2 HEAT-like repeat NUC173 PF08161.7 AIN99906.1 - 0.0018 17.6 0.5 0.066 12.5 0.0 3.4 4 0 0 4 4 4 1 NUC173 domain RIX1 PF08167.7 AIN99906.1 - 0.0059 16.2 0.1 2.3 7.8 0.0 3.3 2 0 0 2 2 2 1 rRNA processing/ribosome biogenesis HEAT PF02985.17 AIN99906.1 - 0.014 15.4 12.8 1.6 9.0 0.0 7.3 8 0 0 8 8 8 0 HEAT repeat Adaptin_N PF01602.15 AIN99906.1 - 0.025 12.9 0.9 3 6.0 0.1 2.7 1 1 0 2 2 2 0 Adaptin N terminal region MMS19_C PF12460.3 AIN99906.1 - 0.099 11.3 0.2 4.5 5.8 0.0 3.3 3 1 0 3 3 3 0 RNAPII transcription regulator C-terminal DHO_dh PF01180.16 AIN99906.1 - 0.1 11.5 0.1 0.19 10.6 0.1 1.4 1 0 0 1 1 1 0 Dihydroorotate dehydrogenase LRR_4 PF12799.2 AIN99907.1 - 7.7e-12 44.5 2.1 0.00044 19.7 0.1 4.4 4 1 1 5 5 5 3 Leucine Rich repeats (2 copies) IQ PF00612.22 AIN99907.1 - 3.2e-09 35.6 11.1 2e-05 23.7 1.9 2.8 2 0 0 2 2 2 2 IQ calmodulin-binding motif LRR_8 PF13855.1 AIN99907.1 - 3.8e-09 36.1 11.2 6.7e-05 22.5 0.1 4.0 4 0 0 4 4 4 2 Leucine rich repeat LRR_1 PF00560.28 AIN99907.1 - 7.5e-06 25.2 7.5 3.1 8.1 0.0 6.0 5 1 0 5 5 5 3 Leucine Rich Repeat LRR_7 PF13504.1 AIN99907.1 - 0.0011 18.8 6.8 10 6.8 0.0 5.8 5 0 0 5 5 5 1 Leucine rich repeat LRR_6 PF13516.1 AIN99907.1 - 0.13 12.4 8.1 41 4.6 0.0 5.3 5 1 1 6 6 6 0 Leucine Rich repeat ADP_ribosyl_GH PF03747.9 AIN99908.1 - 3.3e-11 43.5 2.3 1.6e-07 31.4 0.2 2.9 3 0 0 3 3 3 2 ADP-ribosylglycohydrolase IQ PF00612.22 AIN99909.1 - 8.8e-26 87.0 88.9 8e-05 21.9 1.5 14.2 14 0 0 14 14 14 11 IQ calmodulin-binding motif Adaptin_N PF01602.15 AIN99910.1 - 7.3e-71 239.0 16.0 8.9e-71 238.7 11.1 1.1 1 0 0 1 1 1 1 Adaptin N terminal region COP-gamma_platf PF08752.5 AIN99910.1 - 1.7e-34 118.8 0.1 3.8e-34 117.6 0.1 1.6 1 0 0 1 1 1 1 Coatomer gamma subunit appendage platform subdomain HEAT_2 PF13646.1 AIN99910.1 - 6.9e-06 26.2 10.0 0.059 13.6 0.1 5.0 4 1 2 6 6 6 3 HEAT repeats HEAT PF02985.17 AIN99910.1 - 0.0003 20.6 7.2 7.6 6.9 0.1 5.9 5 0 0 5 5 5 2 HEAT repeat eIF_4G1 PF12152.3 AIN99910.1 - 0.048 13.5 0.0 0.12 12.2 0.0 1.7 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 4G1 SPO22 PF08631.5 AIN99910.1 - 0.059 12.4 5.1 0.036 13.1 0.8 2.3 2 0 0 2 2 2 0 Meiosis protein SPO22/ZIP4 like HEAT_EZ PF13513.1 AIN99910.1 - 0.21 12.1 5.6 3.2 8.3 0.9 3.7 2 1 1 3 3 3 0 HEAT-like repeat MoaC PF01967.16 AIN99912.1 - 4.4e-18 65.2 0.0 6.7e-17 61.4 0.0 2.3 1 1 0 1 1 1 1 MoaC family Flu_PB2 PF00604.12 AIN99912.1 - 0.49 8.1 0.0 0.68 7.7 0.0 1.1 1 0 0 1 1 1 0 Influenza RNA-dependent RNA polymerase subunit PB2 His_Phos_2 PF00328.17 AIN99913.1 - 2.4e-20 73.1 0.1 7.7e-19 68.2 0.0 2.7 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) His_Phos_1 PF00300.17 AIN99913.1 - 0.0014 18.7 0.0 0.0029 17.7 0.0 1.5 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) SelR PF01641.13 AIN99914.1 - 2.1e-39 134.0 0.0 2.5e-39 133.7 0.0 1.0 1 0 0 1 1 1 1 SelR domain DUF2296 PF10058.4 AIN99914.1 - 0.024 14.3 0.5 0.77 9.5 0.0 2.4 2 0 0 2 2 2 0 Predicted integral membrane metal-binding protein (DUF2296) FYVE PF01363.16 AIN99914.1 - 0.073 12.9 1.2 0.14 12.0 0.8 1.4 1 0 0 1 1 1 0 FYVE zinc finger Yippee-Mis18 PF03226.9 AIN99914.1 - 0.13 12.3 2.2 3.2 7.8 0.0 2.4 2 0 0 2 2 2 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly Metallophos PF00149.23 AIN99915.1 - 6.7e-37 126.8 0.2 8.3e-37 126.5 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase VitD-bind_III PF09164.5 AIN99915.1 - 0.0078 15.7 0.7 0.017 14.7 0.5 1.5 1 0 0 1 1 1 1 Vitamin D binding protein, domain III COX15-CtaA PF02628.10 AIN99916.1 - 3.8e-86 288.6 11.7 4.4e-86 288.4 8.1 1.0 1 0 0 1 1 1 1 Cytochrome oxidase assembly protein 2OG-FeII_Oxy_2 PF13532.1 AIN99919.1 - 0.00038 20.3 0.0 0.00052 19.9 0.0 1.2 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily APG12 PF04110.8 AIN99920.1 - 0.04 14.0 0.0 0.21 11.7 0.0 2.0 1 1 1 2 2 2 0 Ubiquitin-like autophagy protein Apg12 DUF179 PF02622.10 AIN99921.1 - 1e-05 25.1 0.2 7.1e-05 22.4 0.0 2.2 2 0 0 2 2 2 1 Uncharacterized ACR, COG1678 WD40 PF00400.27 AIN99922.1 - 2.1e-58 192.2 25.1 2.6e-11 42.9 1.1 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 AIN99922.1 - 3.7e-07 28.6 5.9 0.052 11.6 0.2 3.8 1 1 2 4 4 4 3 Nucleoporin Nup120/160 eIF2A PF08662.6 AIN99922.1 - 2.2e-06 27.4 0.0 0.01 15.5 0.0 3.2 1 1 2 3 3 3 3 Eukaryotic translation initiation factor eIF2A Nucleoporin_N PF08801.6 AIN99922.1 - 0.00012 20.9 1.2 0.48 9.0 0.0 3.8 1 1 2 3 3 3 2 Nup133 N terminal like Cytochrom_D1 PF02239.11 AIN99922.1 - 0.0086 14.4 0.0 1.2 7.3 0.0 2.5 1 1 1 3 3 3 3 Cytochrome D1 heme domain PQQ_2 PF13360.1 AIN99922.1 - 0.024 14.1 0.2 0.15 11.4 0.1 2.4 1 1 2 3 3 3 0 PQQ-like domain PD40 PF07676.7 AIN99922.1 - 0.079 12.6 1.8 6.4 6.5 0.0 4.2 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat Coatomer_WDAD PF04053.9 AIN99922.1 - 0.12 11.1 0.0 0.84 8.3 0.0 1.9 1 1 1 2 2 2 0 Coatomer WD associated region WD40 PF00400.27 AIN99923.1 - 2.1e-58 192.2 25.1 2.6e-11 42.9 1.1 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 AIN99923.1 - 3.7e-07 28.6 5.9 0.052 11.6 0.2 3.8 1 1 2 4 4 4 3 Nucleoporin Nup120/160 eIF2A PF08662.6 AIN99923.1 - 2.2e-06 27.4 0.0 0.01 15.5 0.0 3.2 1 1 2 3 3 3 3 Eukaryotic translation initiation factor eIF2A Nucleoporin_N PF08801.6 AIN99923.1 - 0.00012 20.9 1.2 0.48 9.0 0.0 3.8 1 1 2 3 3 3 2 Nup133 N terminal like Cytochrom_D1 PF02239.11 AIN99923.1 - 0.0086 14.4 0.0 1.2 7.3 0.0 2.5 1 1 1 3 3 3 3 Cytochrome D1 heme domain PQQ_2 PF13360.1 AIN99923.1 - 0.024 14.1 0.2 0.15 11.4 0.1 2.4 1 1 2 3 3 3 0 PQQ-like domain PD40 PF07676.7 AIN99923.1 - 0.079 12.6 1.8 6.4 6.5 0.0 4.2 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat Coatomer_WDAD PF04053.9 AIN99923.1 - 0.12 11.1 0.0 0.84 8.3 0.0 1.9 1 1 1 2 2 2 0 Coatomer WD associated region Spc97_Spc98 PF04130.8 AIN99924.1 - 5.2e-58 196.6 0.1 1e-57 195.7 0.0 1.5 2 0 0 2 2 2 1 Spc97 / Spc98 family HSP70 PF00012.15 AIN99925.1 - 1.9e-271 901.3 4.0 2.1e-271 901.1 2.8 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 AIN99925.1 - 1.3e-13 50.2 0.0 1.7e-12 46.5 0.0 2.1 2 0 0 2 2 2 1 MreB/Mbl protein FtsA PF14450.1 AIN99925.1 - 0.0025 17.6 0.3 0.19 11.5 0.2 3.5 1 1 0 1 1 1 1 Cell division protein FtsA Terminase_4 PF05119.7 AIN99925.1 - 0.027 14.6 1.4 0.24 11.5 0.1 2.5 2 0 0 2 2 2 0 Phage terminase, small subunit Pex19 PF04614.7 AIN99925.1 - 0.066 12.8 3.6 0.15 11.6 2.5 1.5 1 0 0 1 1 1 0 Pex19 protein family FliT PF05400.8 AIN99926.1 - 0.58 10.5 4.7 1 9.8 3.2 1.3 1 0 0 1 1 1 0 Flagellar protein FliT Beta-lactamase PF00144.19 AIN99927.1 - 7.2e-12 44.9 0.1 1.8e-11 43.6 0.1 1.6 1 1 0 1 1 1 1 Beta-lactamase HSP70 PF00012.15 AIN99929.1 - 2.2e-194 646.7 5.6 2.6e-194 646.5 3.9 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 AIN99929.1 - 8.5e-19 67.3 0.6 1e-14 53.8 0.1 2.5 2 0 0 2 2 2 2 MreB/Mbl protein DDR PF08841.5 AIN99929.1 - 0.00057 18.8 0.9 0.0037 16.1 0.6 2.3 1 1 0 1 1 1 1 Diol dehydratase reactivase ATPase-like domain FtsA PF14450.1 AIN99929.1 - 0.0014 18.4 0.0 0.0014 18.4 0.0 3.8 4 1 0 4 4 4 1 Cell division protein FtsA Hydantoinase_A PF01968.13 AIN99929.1 - 4.6 6.2 12.8 0.96 8.4 0.2 3.6 3 2 1 4 4 4 0 Hydantoinase/oxoprolinase zf-C3HC4_3 PF13920.1 AIN99931.1 - 0.91 9.2 7.3 3.3 7.4 1.6 2.6 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) F-box PF00646.28 AIN99932.1 - 0.024 14.2 0.0 0.066 12.8 0.0 1.7 1 0 0 1 1 1 0 F-box domain Ldh_1_C PF02866.13 AIN99933.1 - 4.5e-30 104.6 0.0 7.7e-30 103.8 0.0 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Ldh_1_N PF00056.18 AIN99933.1 - 2.5e-29 101.9 0.1 3.8e-29 101.3 0.1 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Glyco_hydro_31 PF01055.21 AIN99934.1 - 0.046 12.5 0.0 0.064 12.0 0.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolases family 31 Sigma70_r4_2 PF08281.7 AIN99934.1 - 0.17 11.3 0.9 5.7 6.4 0.0 2.9 3 0 0 3 3 3 0 Sigma-70, region 4 Dynein_heavy PF03028.10 AIN99935.1 - 5.2e-187 623.1 0.0 1.8e-186 621.3 0.0 1.9 2 0 0 2 2 2 1 Dynein heavy chain and region D6 of dynein motor DHC_N2 PF08393.8 AIN99935.1 - 3.1e-96 322.4 10.4 6e-96 321.4 0.0 3.8 3 1 0 3 3 3 1 Dynein heavy chain, N-terminal region 2 AAA_6 PF12774.2 AIN99935.1 - 1.9e-85 286.0 0.1 5.7e-85 284.5 0.0 1.9 2 0 0 2 2 2 1 Hydrolytic ATP binding site of dynein motor region D1 AAA_8 PF12780.2 AIN99935.1 - 3.2e-75 252.5 0.0 1.6e-74 250.2 0.0 2.2 2 0 0 2 2 2 1 P-loop containing dynein motor region D4 AAA_9 PF12781.2 AIN99935.1 - 8e-45 152.4 0.1 4.7e-44 149.9 0.0 2.2 1 1 0 1 1 1 1 ATP-binding dynein motor region D5 AAA_7 PF12775.2 AIN99935.1 - 2.6e-44 151.3 0.1 3.4e-43 147.6 0.0 2.4 2 0 0 2 2 2 1 P-loop containing dynein motor region D3 MT PF12777.2 AIN99935.1 - 4.7e-41 140.6 10.7 9.2e-41 139.7 7.4 1.5 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_5 PF07728.9 AIN99935.1 - 5.3e-25 87.7 0.0 5.4e-07 29.4 0.0 6.5 6 1 0 6 6 6 4 AAA domain (dynein-related subfamily) AAA PF00004.24 AIN99935.1 - 1.6e-09 38.0 0.5 0.044 13.9 0.0 5.2 4 0 0 4 4 4 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 AIN99935.1 - 1.8e-06 28.1 3.4 1.8 8.6 0.0 6.1 8 0 0 8 8 5 3 AAA domain AAA_18 PF13238.1 AIN99935.1 - 8.2e-05 22.9 0.0 0.79 10.0 0.0 4.9 4 0 0 4 4 4 1 AAA domain AAA_19 PF13245.1 AIN99935.1 - 0.00011 21.8 2.8 0.36 10.6 0.0 4.2 4 0 0 4 4 4 2 Part of AAA domain AAA_17 PF13207.1 AIN99935.1 - 0.00012 22.8 0.0 0.35 11.7 0.0 5.2 4 0 0 4 4 4 1 AAA domain ResIII PF04851.10 AIN99935.1 - 0.00018 21.4 0.4 0.39 10.5 0.0 4.2 4 0 0 4 4 4 1 Type III restriction enzyme, res subunit AAA_14 PF13173.1 AIN99935.1 - 0.00021 21.1 0.0 0.68 9.8 0.0 3.2 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.1 AIN99935.1 - 0.0011 18.9 19.2 0.56 10.1 0.0 7.2 8 1 0 8 8 6 2 AAA ATPase domain RNA_helicase PF00910.17 AIN99935.1 - 0.0014 18.7 0.0 0.31 11.2 0.0 4.0 3 0 0 3 3 3 1 RNA helicase Dor1 PF04124.7 AIN99937.1 - 5e-24 84.3 3.1 6.4e-24 84.0 2.2 1.1 1 0 0 1 1 1 1 Dor1-like family Sec5 PF15469.1 AIN99937.1 - 0.0047 16.6 0.0 0.0082 15.8 0.0 1.3 1 0 0 1 1 1 1 Exocyst complex component Sec5 ELFV_dehydrog PF00208.16 AIN99938.1 - 7.8e-86 287.6 3.4 1e-85 287.2 2.4 1.1 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ELFV_dehydrog_N PF02812.13 AIN99938.1 - 6.4e-48 161.6 0.0 1.8e-46 156.9 0.0 2.9 4 0 0 4 4 4 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain NAD_binding_7 PF13241.1 AIN99938.1 - 0.0028 17.8 0.1 0.0053 16.9 0.1 1.4 1 0 0 1 1 1 1 Putative NAD(P)-binding Na_sulph_symp PF00939.14 AIN99940.1 - 7.6e-15 54.7 48.8 4.3e-14 52.2 33.8 2.6 1 1 0 1 1 1 1 Sodium:sulfate symporter transmembrane region SPX PF03105.14 AIN99940.1 - 1.6e-12 47.7 10.6 2e-08 34.3 0.3 3.0 1 1 1 2 2 2 2 SPX domain zf-CCCH PF00642.19 AIN99942.1 - 0.072 12.7 8.4 0.49 10.1 0.7 2.7 3 0 0 3 3 3 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Gmad1 PF10647.4 AIN99943.1 - 0.0017 17.8 6.3 0.33 10.3 0.9 2.5 2 1 0 2 2 2 2 Lipoprotein LpqB beta-propeller domain PQQ_2 PF13360.1 AIN99943.1 - 0.43 9.9 5.1 0.73 9.2 0.7 2.3 1 1 1 2 2 2 0 PQQ-like domain PQQ_3 PF13570.1 AIN99943.1 - 1.3 9.3 15.8 7.7 6.9 0.1 5.5 5 1 1 6 6 6 0 PQQ-like domain WD40 PF00400.27 AIN99943.1 - 1.4 8.8 13.4 0.18 11.7 0.8 4.4 5 0 0 5 5 5 0 WD domain, G-beta repeat Pkinase PF00069.20 AIN99947.1 - 6.8e-48 163.0 0.0 8.5e-48 162.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AIN99947.1 - 2.4e-27 95.6 0.0 3.1e-27 95.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 AIN99947.1 - 3.2e-05 23.0 0.0 5.8e-05 22.1 0.0 1.3 1 0 0 1 1 1 1 Kinase-like SMRP1 PF15181.1 AIN99947.1 - 0.14 11.5 0.0 0.2 11.0 0.0 1.2 1 0 0 1 1 1 0 Spermatid-specific manchette-related protein 1 SH3_3 PF08239.6 AIN99947.1 - 0.15 12.2 0.0 0.31 11.2 0.0 1.4 1 0 0 1 1 1 0 Bacterial SH3 domain Acetyltransf_1 PF00583.19 AIN99948.1 - 6e-13 48.6 0.0 8.6e-13 48.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 AIN99948.1 - 1.2e-09 38.1 0.0 1.9e-09 37.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 AIN99948.1 - 0.00011 22.0 0.0 0.00014 21.6 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 AIN99948.1 - 0.00062 19.8 0.0 0.00074 19.6 0.0 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 AIN99948.1 - 0.0081 16.0 0.0 0.011 15.5 0.0 1.3 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_8 PF13523.1 AIN99948.1 - 0.085 12.7 0.0 0.14 12.0 0.0 1.5 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain CARD PF00619.16 AIN99948.1 - 0.088 12.6 0.1 0.15 11.8 0.0 1.4 1 0 0 1 1 1 0 Caspase recruitment domain Cytochrome_CBB3 PF13442.1 AIN99950.1 - 3.4 7.8 8.1 2.6 8.2 0.2 2.7 2 0 0 2 2 2 0 Cytochrome C oxidase, cbb3-type, subunit III ECH PF00378.15 AIN99951.1 - 3.1e-37 128.0 0.0 3.9e-37 127.6 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family SPT16 PF08644.6 AIN99952.1 - 2.3e-35 121.7 1.6 4.9e-35 120.6 0.0 2.2 2 0 0 2 2 2 1 FACT complex subunit (SPT16/CDC68) Rtt106 PF08512.7 AIN99952.1 - 6.9e-15 54.7 0.4 5.2e-14 51.9 0.0 2.4 2 0 0 2 2 2 1 Histone chaperone Rttp106-like Peptidase_M24 PF00557.19 AIN99952.1 - 5.6e-14 52.2 0.0 1e-13 51.3 0.0 1.5 1 0 0 1 1 1 1 Metallopeptidase family M24 KR PF08659.5 AIN99952.1 - 0.096 12.3 5.2 0.02 14.5 0.9 1.8 2 0 0 2 2 2 0 KR domain Nop14 PF04147.7 AIN99952.1 - 3.3 5.5 19.8 7 4.4 13.7 1.5 1 0 0 1 1 1 0 Nop14-like family Daxx PF03344.10 AIN99952.1 - 9.2 4.6 14.4 18 3.6 10.0 1.4 1 0 0 1 1 1 0 Daxx Family Ribosomal_L3 PF00297.17 AIN99953.1 - 1.6e-13 50.6 0.1 2.7e-13 49.9 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L3 TPR_2 PF07719.12 AIN99953.1 - 0.24 11.4 1.2 0.72 9.9 0.8 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat tRNA-synt_1b PF00579.20 AIN99956.1 - 7.9e-20 71.1 0.0 2.5e-19 69.5 0.0 1.7 1 1 0 1 1 1 1 tRNA synthetases class I (W and Y) SNARE PF05739.14 AIN99957.1 - 2.8e-12 46.1 7.8 4.3e-12 45.5 3.7 2.3 2 0 0 2 2 2 1 SNARE domain RmuC PF02646.11 AIN99957.1 - 0.014 14.2 1.4 0.014 14.2 1.0 2.2 2 1 0 2 2 2 0 RmuC family Synaptobrevin PF00957.16 AIN99957.1 - 0.025 14.1 3.7 0.028 14.0 0.4 2.2 2 0 0 2 2 2 0 Synaptobrevin DUF1664 PF07889.7 AIN99957.1 - 0.061 13.1 3.8 0.74 9.6 0.2 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) DUF4238 PF14022.1 AIN99957.1 - 0.07 12.3 2.2 0.043 13.0 0.3 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF4238) MCPsignal PF00015.16 AIN99957.1 - 0.35 10.3 9.1 0.19 11.2 1.4 2.3 1 1 0 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain TMPIT PF07851.8 AIN99957.1 - 0.65 9.0 3.2 0.84 8.6 0.2 2.0 2 0 0 2 2 2 0 TMPIT-like protein V_ATPase_I PF01496.14 AIN99957.1 - 0.87 7.3 12.6 0.27 9.0 5.5 2.1 1 1 1 2 2 2 0 V-type ATPase 116kDa subunit family Syntaxin_2 PF14523.1 AIN99957.1 - 1.5 8.8 13.7 0.29 11.1 1.4 2.6 3 0 0 3 3 3 0 Syntaxin-like protein DUF4559 PF15112.1 AIN99957.1 - 5.9 5.9 10.1 2.7 7.0 2.8 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4559) Sen15 PF09631.5 AIN99958.1 - 0.15 12.3 0.0 0.17 12.0 0.0 1.2 1 0 0 1 1 1 0 Sen15 protein Ras PF00071.17 AIN99959.1 - 2.1e-34 118.2 0.2 2.4e-34 118.0 0.1 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 AIN99959.1 - 2.8e-14 53.6 0.1 3.8e-14 53.2 0.1 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 AIN99959.1 - 1.6e-10 40.5 0.0 2e-10 40.1 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 AIN99959.1 - 2.4e-07 30.1 0.1 3.1e-07 29.7 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 AIN99959.1 - 1.6e-06 27.6 0.2 6.8e-06 25.6 0.1 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain PduV-EutP PF10662.4 AIN99959.1 - 0.0022 17.4 0.0 0.3 10.5 0.0 2.1 2 0 0 2 2 2 2 Ethanolamine utilisation - propanediol utilisation MMR_HSR1 PF01926.18 AIN99959.1 - 0.0082 16.0 0.0 0.013 15.4 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase TDH PF03347.8 AIN99959.1 - 0.01 15.3 0.2 0.018 14.5 0.1 1.4 2 0 0 2 2 2 0 Vibrio thermostable direct hemolysin G-alpha PF00503.15 AIN99959.1 - 0.075 11.7 0.0 0.37 9.4 0.0 1.9 2 0 0 2 2 2 0 G-protein alpha subunit FeoB_N PF02421.13 AIN99959.1 - 0.16 11.2 0.5 1.7 7.9 0.3 2.4 1 1 0 1 1 1 0 Ferrous iron transport protein B WD40 PF00400.27 AIN99960.1 - 3.4e-12 45.7 3.2 0.019 14.8 0.0 6.0 6 0 0 6 6 6 4 WD domain, G-beta repeat DUF2139 PF09910.4 AIN99960.1 - 0.061 12.3 0.0 0.11 11.4 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2139) tify PF06200.9 AIN99960.1 - 0.13 11.4 1.9 2.5 7.4 0.1 3.1 3 0 0 3 3 3 0 tify domain DOCK-C2 PF14429.1 AIN99961.1 - 7e-34 117.0 0.0 2.6e-33 115.1 0.0 2.1 2 0 0 2 2 2 1 C2 domain in Dock180 and Zizimin proteins Ded_cyto PF06920.8 AIN99961.1 - 0.02 14.1 0.0 0.045 13.0 0.0 1.5 1 0 0 1 1 1 0 Dedicator of cytokinesis Wyosine_form PF08608.7 AIN99961.1 - 0.047 13.7 0.0 0.26 11.4 0.0 2.3 1 0 0 1 1 1 0 Wyosine base formation DDHD PF02862.12 AIN99962.1 - 6.9 6.3 9.0 9.8 5.8 6.2 1.4 1 1 0 1 1 1 0 DDHD domain PC_rep PF01851.17 AIN99963.1 - 6.9e-22 76.3 17.4 3.1e-05 23.9 0.0 9.1 11 0 0 11 11 11 4 Proteasome/cyclosome repeat HEAT_EZ PF13513.1 AIN99963.1 - 1.8 9.1 10.2 21 5.7 0.1 5.1 5 1 1 6 6 6 0 HEAT-like repeat IQ PF00612.22 AIN99964.1 - 0.093 12.4 10.8 0.2 11.3 1.8 2.9 2 0 0 2 2 2 0 IQ calmodulin-binding motif RNA_pol_A_bac PF01000.21 AIN99965.1 - 8.6e-20 70.9 0.0 1.4e-19 70.2 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.19 AIN99965.1 - 5.1e-14 51.1 0.0 6.9e-14 50.7 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Fer4_9 PF13187.1 AIN99965.1 - 0.0099 16.1 1.7 0.0099 16.1 1.2 2.1 2 0 0 2 2 2 1 4Fe-4S dicluster domain TPR_19 PF14559.1 AIN99966.1 - 2e-17 63.2 12.1 0.00077 19.7 0.2 6.0 6 1 1 7 7 5 4 Tetratricopeptide repeat TPR_11 PF13414.1 AIN99966.1 - 5.4e-17 61.2 15.2 7.6e-06 25.4 0.4 6.1 4 2 2 6 6 6 5 TPR repeat TPR_12 PF13424.1 AIN99966.1 - 1.5e-12 47.2 12.2 6.6e-05 22.7 0.2 6.6 7 1 2 9 9 9 2 Tetratricopeptide repeat TPR_2 PF07719.12 AIN99966.1 - 7.8e-12 44.1 15.5 0.00017 21.2 0.0 8.7 8 0 0 8 8 8 3 Tetratricopeptide repeat Apc3 PF12895.2 AIN99966.1 - 6.1e-11 42.3 18.6 1.2e-07 31.7 2.7 5.2 4 2 1 5 5 5 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_1 PF00515.23 AIN99966.1 - 7.3e-09 34.8 9.6 0.032 13.8 0.1 7.0 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_14 PF13428.1 AIN99966.1 - 8e-09 35.3 6.6 0.085 13.5 0.1 7.5 6 2 2 8 8 7 2 Tetratricopeptide repeat TPR_16 PF13432.1 AIN99966.1 - 4.2e-08 33.6 15.5 5.6e-07 30.0 0.1 6.3 4 2 4 8 8 8 1 Tetratricopeptide repeat TPR_6 PF13174.1 AIN99966.1 - 8.1e-08 32.2 12.7 0.023 15.1 0.0 7.7 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_10 PF13374.1 AIN99966.1 - 0.00029 20.6 11.9 0.66 9.9 0.0 6.2 7 0 0 7 7 6 2 Tetratricopeptide repeat TPR_7 PF13176.1 AIN99966.1 - 0.00048 19.7 6.7 2.7 8.0 0.0 6.8 7 0 0 7 7 6 1 Tetratricopeptide repeat TPR_9 PF13371.1 AIN99966.1 - 0.00066 19.4 4.1 0.017 14.9 0.4 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.1 AIN99966.1 - 0.0028 17.2 7.1 0.7 9.8 0.1 5.7 6 0 0 6 6 5 1 Tetratricopeptide repeat TPR_3 PF07720.7 AIN99966.1 - 0.0062 16.3 0.1 0.0062 16.3 0.1 3.5 4 0 0 4 4 2 1 Tetratricopeptide repeat Foie-gras_1 PF11817.3 AIN99966.1 - 0.0095 15.4 5.6 0.25 10.7 0.1 3.3 3 0 0 3 3 3 1 Foie gras liver health family 1 PPR PF01535.15 AIN99966.1 - 0.014 15.3 6.3 16 5.7 0.0 4.8 5 0 0 5 5 4 0 PPR repeat HrpB1_HrpK PF09613.5 AIN99966.1 - 0.028 13.9 0.9 0.18 11.3 0.0 2.8 3 0 0 3 3 3 0 Bacterial type III secretion protein (HrpB1_HrpK) PPR_3 PF13812.1 AIN99966.1 - 0.038 14.2 1.8 54 4.4 0.0 4.9 4 0 0 4 4 3 0 Pentatricopeptide repeat domain NARP1 PF12569.3 AIN99966.1 - 0.063 12.0 9.5 0.21 10.2 0.5 3.0 3 1 1 4 4 4 0 NMDA receptor-regulated protein 1 Fis1_TPR_C PF14853.1 AIN99966.1 - 1.7 8.5 16.5 5.8 6.8 0.2 4.9 3 1 2 5 5 4 0 Fis1 C-terminal tetratricopeptide repeat TPR_17 PF13431.1 AIN99966.1 - 6.1 7.3 6.6 1e+02 3.4 0.2 4.9 6 0 0 6 6 4 0 Tetratricopeptide repeat IPP-2 PF04979.9 AIN99968.1 - 2.5e-08 34.2 5.3 5.5e-08 33.1 3.6 1.5 1 1 0 1 1 1 1 Protein phosphatase inhibitor 2 (IPP-2) zf-RanBP PF00641.13 AIN99969.1 - 0.0068 15.4 7.1 0.0068 15.4 4.9 1.7 2 0 0 2 2 2 1 Zn-finger in Ran binding protein and others RRM_1 PF00076.17 AIN99969.1 - 0.034 13.7 0.0 0.069 12.8 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SNF2_N PF00176.18 AIN99971.1 - 3.7e-32 111.3 0.1 6.6e-32 110.4 0.1 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 AIN99971.1 - 1.2e-06 28.2 0.1 3.4e-06 26.8 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 AIN99971.1 - 1.9e-05 24.5 0.0 0.032 14.0 0.0 2.5 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit AAA_22 PF13401.1 AIN99971.1 - 0.039 14.0 0.1 0.15 12.1 0.1 2.0 1 0 0 1 1 1 0 AAA domain DEAD PF00270.24 AIN99971.1 - 0.13 11.7 0.1 1.5 8.3 0.0 2.4 2 0 0 2 2 2 0 DEAD/DEAH box helicase DUF2075 PF09848.4 AIN99971.1 - 0.39 9.6 0.3 0.96 8.3 0.0 1.6 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) HemY_N PF07219.8 AIN99972.1 - 0.81 9.2 8.8 0.26 10.8 0.2 2.7 2 1 0 2 2 2 0 HemY protein N-terminus Sec23_trunk PF04811.10 AIN99973.1 - 4.2e-43 147.4 0.0 7.1e-43 146.7 0.0 1.3 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_BS PF08033.7 AIN99973.1 - 1.4e-20 73.6 0.0 3.4e-20 72.3 0.0 1.7 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.10 AIN99973.1 - 4.6e-16 58.0 2.5 4.6e-16 58.0 1.7 2.0 2 0 0 2 2 2 1 Sec23/Sec24 zinc finger Sec23_helical PF04815.10 AIN99973.1 - 7.3e-08 31.7 0.0 1.5e-07 30.7 0.0 1.5 1 0 0 1 1 1 1 Sec23/Sec24 helical domain RIO1 PF01163.17 AIN99975.1 - 1.3e-65 220.2 0.6 2.1e-65 219.6 0.0 1.6 2 0 0 2 2 2 1 RIO1 family APH PF01636.18 AIN99975.1 - 0.019 14.7 0.4 0.21 11.2 0.2 2.4 1 1 1 2 2 2 0 Phosphotransferase enzyme family DUF552 PF04472.7 AIN99975.1 - 0.097 12.5 0.1 27 4.7 0.0 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF552) CDC45 PF02724.9 AIN99975.1 - 4.4 5.2 14.2 6.9 4.5 9.8 1.2 1 0 0 1 1 1 0 CDC45-like protein Sigma70_ner PF04546.8 AIN99975.1 - 8.4 5.9 14.0 5.9 6.4 8.1 1.9 2 0 0 2 2 2 0 Sigma-70, non-essential region DIOX_N PF14226.1 AIN99976.1 - 3.5e-33 114.5 0.0 5.3e-33 113.9 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 AIN99976.1 - 7e-24 84.0 0.0 1.3e-23 83.1 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily TTL PF03133.10 AIN99977.1 - 2.3e-41 141.6 0.0 1.1e-17 63.9 0.0 3.1 3 0 0 3 3 3 3 Tubulin-tyrosine ligase family zf-C2HC_2 PF13913.1 AIN99979.1 - 8.6e-17 60.3 8.1 1.5e-09 37.2 1.0 2.4 2 0 0 2 2 2 2 zinc-finger of a C2HC-type zf-Di19 PF05605.7 AIN99979.1 - 0.00017 21.6 2.6 0.028 14.5 0.4 2.5 2 0 0 2 2 2 1 Drought induced 19 protein (Di19), zinc-binding zf-C2H2 PF00096.21 AIN99979.1 - 0.0011 19.2 4.4 0.29 11.5 0.7 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 AIN99979.1 - 0.0022 18.1 5.3 2.1 8.8 0.0 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 AIN99979.1 - 0.0026 17.9 1.2 3.1 8.2 0.1 2.7 2 0 0 2 2 2 2 Zinc-finger double domain Nairovirus_M PF07948.6 AIN99979.1 - 0.0033 15.6 4.6 0.11 10.5 0.6 2.1 2 0 0 2 2 2 2 Nairovirus M polyprotein-like Sgf11 PF08209.6 AIN99979.1 - 0.004 16.4 5.0 0.093 12.0 0.3 2.5 2 0 0 2 2 2 1 Sgf11 (transcriptional regulation protein) Zn-ribbon_8 PF09723.5 AIN99979.1 - 0.012 15.5 1.5 3.8 7.5 0.1 2.8 2 0 0 2 2 2 0 Zinc ribbon domain Tmemb_55A PF09788.4 AIN99979.1 - 0.013 14.6 0.4 0.03 13.4 0.3 1.6 1 0 0 1 1 1 0 Transmembrane protein 55A zf-FPG_IleRS PF06827.9 AIN99979.1 - 0.021 14.4 8.6 0.53 9.9 1.1 2.6 2 0 0 2 2 2 0 Zinc finger found in FPG and IleRS zf-ribbon_3 PF13248.1 AIN99979.1 - 0.021 13.9 4.8 2.5 7.4 0.0 3.1 2 1 0 2 2 2 0 zinc-ribbon domain zf-CHCC PF10276.4 AIN99979.1 - 0.043 13.6 1.3 5.8 6.8 0.1 2.6 2 0 0 2 2 2 0 Zinc-finger domain DUF164 PF02591.10 AIN99979.1 - 0.043 13.6 0.9 11 5.9 0.1 2.9 2 0 0 2 2 2 0 Putative zinc ribbon domain zinc_ribbon_2 PF13240.1 AIN99979.1 - 0.055 12.9 3.2 10 5.7 1.2 2.8 2 1 0 2 2 2 0 zinc-ribbon domain NAD_binding_10 PF13460.1 AIN99979.1 - 0.055 13.4 0.1 0.094 12.7 0.1 1.3 1 0 0 1 1 1 0 NADH(P)-binding Lar_restr_allev PF14354.1 AIN99979.1 - 0.068 13.4 2.8 1.9 8.8 0.3 3.0 3 0 0 3 3 3 0 Restriction alleviation protein Lar HypA PF01155.14 AIN99979.1 - 0.071 12.8 0.7 13 5.4 0.1 2.4 2 0 0 2 2 2 0 Hydrogenase expression/synthesis hypA family zf-RING_3 PF14369.1 AIN99979.1 - 0.17 11.8 7.6 3 7.9 0.3 3.4 4 0 0 4 4 3 0 zinc-finger DUF329 PF03884.9 AIN99979.1 - 0.18 11.4 2.4 1.6 8.3 0.5 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF329) TerY-C PF15616.1 AIN99979.1 - 0.37 10.7 2.7 2.9 7.8 0.0 2.7 3 0 0 3 3 3 0 TerY-C metal binding domain zf-C2H2_6 PF13912.1 AIN99979.1 - 0.44 10.5 1.9 16 5.5 0.0 2.4 2 0 0 2 2 2 0 C2H2-type zinc finger Zn_Tnp_IS1595 PF12760.2 AIN99979.1 - 0.73 9.6 3.6 6.4 6.6 0.6 2.4 2 0 0 2 2 2 0 Transposase zinc-ribbon domain FHA PF00498.21 AIN99980.1 - 1.2e-06 28.5 0.0 0.021 14.9 0.0 2.3 2 0 0 2 2 2 2 FHA domain TPR_11 PF13414.1 AIN99981.1 - 1.1e-10 40.9 6.4 5.1e-08 32.4 0.6 3.1 3 1 1 4 4 4 2 TPR repeat TPR_16 PF13432.1 AIN99981.1 - 0.00019 22.0 3.7 0.014 16.0 0.8 4.1 3 2 1 4 4 4 2 Tetratricopeptide repeat TPR_9 PF13371.1 AIN99981.1 - 0.0012 18.7 2.3 0.0026 17.5 0.2 2.6 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.23 AIN99981.1 - 0.0049 16.4 0.1 14 5.5 0.2 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_17 PF13431.1 AIN99981.1 - 0.023 14.8 0.1 8.1 6.9 0.0 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat HTH_IclR PF09339.5 AIN99981.1 - 0.024 14.2 0.3 0.08 12.5 0.2 1.9 1 0 0 1 1 1 0 IclR helix-turn-helix domain TPR_2 PF07719.12 AIN99981.1 - 0.038 13.8 0.0 0.4 10.7 0.0 4.4 5 0 0 5 5 5 0 Tetratricopeptide repeat Calc_CGRP_IAPP PF00214.14 AIN99981.1 - 0.15 12.0 1.6 0.34 10.9 1.1 1.6 1 0 0 1 1 1 0 Calcitonin / CGRP / IAPP family DUF2999 PF11212.3 AIN99981.1 - 0.24 11.4 5.7 26 4.9 3.5 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF2999) ArfGap PF01412.13 AIN99982.1 - 5.3e-38 129.4 0.1 1.1e-37 128.3 0.0 1.6 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf OrfB_Zn_ribbon PF07282.6 AIN99982.1 - 0.091 12.4 1.7 0.21 11.2 1.2 1.6 1 0 0 1 1 1 0 Putative transposase DNA-binding domain RRN7 PF11781.3 AIN99982.1 - 0.21 11.0 3.9 0.45 10.0 2.7 1.5 1 0 0 1 1 1 0 RNA polymerase I-specific transcription initiation factor Rrn7 UBA_4 PF14555.1 AIN99983.1 - 1.4e-06 27.6 0.1 3e-06 26.6 0.1 1.5 1 0 0 1 1 1 1 UBA-like domain Thioredoxin_7 PF13899.1 AIN99983.1 - 0.0033 17.4 0.0 0.01 15.8 0.0 1.8 1 0 0 1 1 1 1 Thioredoxin-like IQ PF00612.22 AIN99984.1 - 0.15 11.7 9.1 1 9.2 2.8 3.4 2 0 0 2 2 2 0 IQ calmodulin-binding motif zf-met PF12874.2 AIN99985.1 - 0.0038 17.3 0.5 0.0071 16.5 0.3 1.4 1 0 0 1 1 1 1 Zinc-finger of C2H2 type Pkinase PF00069.20 AIN99986.1 - 7.7e-40 136.6 0.0 1e-19 70.7 0.0 3.2 3 0 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.12 AIN99986.1 - 9.3e-21 74.0 0.0 4.2e-12 45.6 0.0 3.0 3 0 0 3 3 3 2 Protein tyrosine kinase Kinase-like PF14531.1 AIN99986.1 - 0.0036 16.2 0.2 2 7.3 0.0 2.6 3 0 0 3 3 3 2 Kinase-like Pox_ser-thr_kin PF05445.6 AIN99986.1 - 0.015 14.1 0.1 0.022 13.5 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase APH PF01636.18 AIN99986.1 - 0.017 14.8 0.9 0.085 12.5 0.2 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family RIO1 PF01163.17 AIN99986.1 - 0.38 10.0 0.0 0.74 9.1 0.0 1.3 1 0 0 1 1 1 0 RIO1 family DUF3451 PF11933.3 AIN99987.1 - 5.8e-34 117.8 1.7 1.6e-33 116.4 1.2 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF3451) DUF3250 PF11618.3 AIN99987.1 - 0.0078 16.3 0.0 0.0078 16.3 0.0 4.1 4 1 1 5 5 5 1 Protein of unknown function (DUF3250) RRM_1 PF00076.17 AIN99988.1 - 6.8e-15 54.4 0.1 9.1e-07 28.4 0.1 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 AIN99988.1 - 1.8e-09 37.4 0.2 0.0011 18.8 0.1 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 AIN99988.1 - 2.7e-07 30.3 0.2 0.0004 20.1 0.1 2.6 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 AIN99988.1 - 0.013 15.2 0.2 0.58 9.9 0.0 2.5 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif RNA_pol_Rpb4 PF03874.11 AIN99989.1 - 1.3e-05 25.2 0.0 3.7e-05 23.7 0.0 1.6 2 0 0 2 2 2 1 RNA polymerase Rpb4 Prolamin_like PF05617.6 AIN99989.1 - 0.03 14.4 0.0 0.056 13.5 0.0 1.5 1 0 0 1 1 1 0 Prolamin-like zf-CCCH PF00642.19 AIN99991.1 - 0.032 13.9 0.4 0.049 13.3 0.3 1.3 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) PPR_3 PF13812.1 AIN99992.1 - 0.00021 21.2 1.0 0.26 11.6 0.0 4.7 5 0 0 5 5 5 1 Pentatricopeptide repeat domain PPR_1 PF12854.2 AIN99992.1 - 0.016 14.6 0.1 0.12 11.9 0.0 2.2 2 0 0 2 2 2 0 PPR repeat PPR PF01535.15 AIN99992.1 - 0.019 14.8 0.0 19 5.5 0.0 3.7 3 0 0 3 3 3 0 PPR repeat PPR_2 PF13041.1 AIN99992.1 - 0.079 12.9 0.0 0.46 10.4 0.0 2.4 2 1 1 3 3 3 0 PPR repeat family Metallophos_2 PF12850.2 AIN99993.1 - 0.023 14.5 0.0 0.033 14.0 0.0 1.3 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.23 AIN99993.1 - 0.047 13.0 0.0 0.29 10.4 0.0 2.1 1 1 0 1 1 1 0 Calcineurin-like phosphoesterase Rad51 PF08423.6 AIN99994.1 - 1.8e-10 40.1 0.6 2.6e-05 23.2 0.0 3.2 2 1 0 2 2 2 2 Rad51 RecA PF00154.16 AIN99994.1 - 4.1e-07 29.3 0.8 8e-07 28.4 0.0 1.8 2 0 0 2 2 2 1 recA bacterial DNA recombination protein KaiC PF06745.8 AIN99994.1 - 3.6e-06 26.2 0.0 6.2e-06 25.4 0.0 1.3 1 0 0 1 1 1 1 KaiC AAA_25 PF13481.1 AIN99994.1 - 0.005 16.2 8.0 0.63 9.4 6.2 2.8 2 1 0 2 2 2 1 AAA domain CpeS PF09367.5 AIN99994.1 - 0.11 12.4 0.0 0.24 11.2 0.0 1.5 1 0 0 1 1 1 0 CpeS-like protein AAA_23 PF13476.1 AIN99995.1 - 4.8 7.4 7.3 10 6.3 1.8 2.3 2 0 0 2 2 2 0 AAA domain Gly-zipper_Omp PF13488.1 AIN99996.1 - 0.053 13.1 11.9 0.035 13.7 5.2 2.4 2 0 0 2 2 2 0 Glycine zipper Gly-zipper_OmpA PF13436.1 AIN99996.1 - 0.059 13.0 0.3 0.059 13.0 0.2 3.5 5 0 0 5 5 5 0 Glycine-zipper containing OmpA-like membrane domain DUF164 PF02591.10 AIN99997.1 - 1.4 8.8 4.0 0.91 9.4 0.1 2.6 3 0 0 3 3 3 0 Putative zinc ribbon domain Cofilin_ADF PF00241.15 AIO00001.1 - 2e-28 98.8 0.1 2.2e-28 98.6 0.1 1.0 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein RNase_T PF00929.19 AIO00004.1 - 2.1e-23 83.4 0.0 8.4e-21 74.9 0.0 2.2 1 1 0 1 1 1 1 Exonuclease LIN37 PF15306.1 AIO00004.1 - 0.3 11.0 2.5 0.94 9.4 0.0 2.5 2 0 0 2 2 2 0 LIN37 RNase_T PF00929.19 AIO00005.1 - 9.2e-24 84.5 0.0 1.4e-23 83.9 0.0 1.3 1 0 0 1 1 1 1 Exonuclease RNase_T PF00929.19 AIO00006.1 - 4.3e-26 92.1 0.0 7e-26 91.4 0.0 1.4 1 0 0 1 1 1 1 Exonuclease Ank_2 PF12796.2 AIO00007.1 - 2.6e-11 43.7 0.4 1.3e-10 41.4 0.3 2.2 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 AIO00007.1 - 1.5e-09 38.0 0.1 0.00055 20.3 0.0 3.1 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 AIO00007.1 - 4.5e-08 32.5 1.5 0.038 14.2 0.1 3.9 3 0 0 3 3 3 3 Ankyrin repeat Ank PF00023.25 AIO00007.1 - 1.1e-07 31.2 3.4 0.077 12.8 0.1 3.9 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.1 AIO00007.1 - 0.00091 19.3 4.0 0.18 12.0 0.3 3.7 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Spatacsin_C PF14649.1 AIO00007.1 - 0.088 11.6 0.5 0.18 10.6 0.0 1.7 1 1 1 2 2 2 0 Spatacsin C-terminus ResIII PF04851.10 AIO00009.1 - 1.8e-13 50.7 0.0 3.1e-13 49.9 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.26 AIO00009.1 - 3.5e-08 33.2 0.0 9.3e-08 31.8 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Helicase_C_3 PF13625.1 AIO00009.1 - 1.9e-07 30.8 0.0 5.1e-07 29.5 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 AIO00009.1 - 1.4e-05 24.0 0.0 2.5e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain DEAD PF00270.24 AIO00009.1 - 0.00055 19.4 0.0 0.0009 18.7 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase zf-NF-X1 PF01422.12 AIO00010.1 - 4.8e-06 26.4 82.8 6.9e-05 22.7 12.0 13.7 14 2 1 15 15 15 6 NF-X1 type zinc finger zf-CCHC_2 PF13696.1 AIO00011.1 - 2.5e-05 23.6 0.4 8.5e-05 21.9 0.3 2.0 1 0 0 1 1 1 1 Zinc knuckle zf-C2H2_jaz PF12171.3 AIO00011.1 - 6.8e-05 22.8 0.6 0.00018 21.5 0.3 1.8 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding NUFIP1 PF10453.4 AIO00011.1 - 0.0098 15.3 0.0 0.028 13.9 0.0 1.7 1 0 0 1 1 1 1 Nuclear fragile X mental retardation-interacting protein 1 (NUFIP1) zf-C2H2 PF00096.21 AIO00011.1 - 0.015 15.5 1.6 1 9.8 0.1 3.4 2 0 0 2 2 2 0 Zinc finger, C2H2 type eIF3g PF12353.3 AIO00011.1 - 0.028 14.3 0.1 0.078 12.8 0.1 1.8 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit G zf-LITAF-like PF10601.4 AIO00011.1 - 0.029 14.2 1.3 0.03 14.1 0.1 1.7 2 0 0 2 2 2 0 LITAF-like zinc ribbon domain zf-CCHC_5 PF14787.1 AIO00011.1 - 0.041 13.3 1.6 0.11 12.0 1.1 1.7 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger zf-met PF12874.2 AIO00011.1 - 0.088 13.0 0.2 0.24 11.6 0.1 1.8 1 0 0 1 1 1 0 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.1 AIO00011.1 - 0.19 12.1 0.2 0.19 12.1 0.2 3.7 2 1 1 3 3 3 0 C2H2-type zinc finger zf-C2H2_6 PF13912.1 AIO00011.1 - 0.77 9.7 5.3 0.21 11.5 0.2 2.4 2 0 0 2 2 2 0 C2H2-type zinc finger ABC_tran PF00005.22 AIO00012.1 - 2.1e-57 193.2 0.0 2.5e-27 95.8 0.0 2.3 2 0 0 2 2 2 2 ABC transporter ABC2_membrane_3 PF12698.2 AIO00012.1 - 1.5e-54 185.3 55.1 1.6e-36 126.0 16.0 3.3 3 1 0 3 3 3 2 ABC-2 family transporter protein AAA_21 PF13304.1 AIO00012.1 - 1.1e-12 48.5 1.7 0.0011 18.9 0.0 4.5 3 1 0 4 4 4 3 AAA domain SMC_N PF02463.14 AIO00012.1 - 7e-09 35.2 1.3 0.00013 21.2 0.0 3.4 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 AIO00012.1 - 6.5e-06 25.5 2.1 0.0023 17.4 0.2 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain DUF258 PF03193.11 AIO00012.1 - 0.00066 18.8 0.4 0.51 9.5 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 SbcCD_C PF13558.1 AIO00012.1 - 0.0015 18.4 0.1 0.53 10.2 0.0 3.0 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_23 PF13476.1 AIO00012.1 - 0.0025 18.1 0.5 0.27 11.5 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.1 AIO00012.1 - 0.0064 15.9 0.1 3.4 7.0 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_30 PF13604.1 AIO00012.1 - 0.019 14.5 1.3 0.76 9.3 0.1 2.3 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.1 AIO00012.1 - 0.039 13.8 1.3 12 5.7 0.0 3.2 3 1 0 3 3 2 0 AAA domain Arf PF00025.16 AIO00012.1 - 0.042 13.0 0.1 0.37 10.0 0.0 2.2 2 0 0 2 2 2 0 ADP-ribosylation factor family AAA_15 PF13175.1 AIO00012.1 - 0.1 11.6 0.0 42 3.0 0.0 3.5 4 0 0 4 4 4 0 AAA ATPase domain ABC2_membrane_2 PF12679.2 AIO00012.1 - 0.15 10.8 28.0 0.053 12.3 5.6 2.8 2 1 0 2 2 2 0 ABC-2 family transporter protein AAA_17 PF13207.1 AIO00012.1 - 0.34 11.7 0.1 14 6.5 0.0 2.6 2 0 0 2 2 2 0 AAA domain UPF0079 PF02367.12 AIO00012.1 - 0.49 10.0 2.6 17 5.0 0.2 2.6 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 SRP54 PF00448.17 AIO00012.1 - 0.5 9.7 3.1 2.4 7.5 0.3 2.2 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_13 PF13166.1 AIO00012.1 - 0.99 7.7 0.3 22 3.3 0.1 2.1 2 0 0 2 2 2 0 AAA domain SNARE PF05739.14 AIO00013.1 - 1.1e-07 31.4 1.4 1.5e-07 31.0 0.9 1.1 1 0 0 1 1 1 1 SNARE domain YukC PF10140.4 AIO00013.1 - 0.11 11.0 0.0 0.12 10.8 0.0 1.1 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukC DcpS_C PF11969.3 AIO00014.1 - 2.7e-23 82.3 0.6 8e-23 80.8 0.3 1.7 2 0 0 2 2 2 1 Scavenger mRNA decapping enzyme C-term binding HIT PF01230.18 AIO00014.1 - 2.4e-13 50.4 0.1 8.4e-13 48.6 0.0 1.8 2 0 0 2 2 2 1 HIT domain PHO4 PF01384.15 AIO00015.1 - 2.9e-94 315.3 17.0 3.7e-94 315.0 11.8 1.1 1 0 0 1 1 1 1 Phosphate transporter family Radial_spoke PF04712.7 AIO00016.1 - 8.3e-137 456.8 0.0 1e-136 456.6 0.0 1.1 1 0 0 1 1 1 1 Radial spokehead-like protein RRM_1 PF00076.17 AIO00018.1 - 5.8e-22 77.1 0.0 1.4e-13 50.2 0.0 3.5 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 AIO00018.1 - 6.9e-18 64.4 0.0 4.1e-09 36.3 0.0 3.5 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 AIO00018.1 - 3.2e-15 55.7 0.0 0.00035 20.3 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RHD3 PF05879.7 AIO00019.1 - 0.004 15.1 0.0 0.0052 14.7 0.0 1.0 1 0 0 1 1 1 1 Root hair defective 3 GTP-binding protein (RHD3) CLAMP PF14769.1 AIO00020.1 - 0.0064 16.6 0.0 0.32 11.1 0.0 2.6 2 0 0 2 2 2 1 Flagellar C1a complex subunit C1a-32 BBS2_Mid PF14783.1 AIO00021.1 - 0.00015 21.4 0.1 0.46 10.2 0.0 2.8 2 0 0 2 2 2 2 Ciliary BBSome complex subunit 2, middle region FG-GAP PF01839.18 AIO00021.1 - 0.0025 17.4 0.6 0.0025 17.4 0.4 2.8 3 0 0 3 3 3 1 FG-GAP repeat BBS2_C PF14782.1 AIO00021.1 - 0.0049 15.4 0.8 0.21 10.1 0.0 2.6 3 0 0 3 3 3 2 Ciliary BBSome complex subunit 2, C-terminal VCBS PF13517.1 AIO00021.1 - 0.031 14.6 0.0 0.11 12.8 0.0 2.0 1 0 0 1 1 1 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella EF_TS PF00889.14 AIO00022.1 - 4.2e-16 58.9 0.0 9e-16 57.8 0.0 1.6 1 1 1 2 2 2 1 Elongation factor TS Glyoxalase_4 PF13669.1 AIO00022.1 - 0.045 13.7 0.1 2.8 7.9 0.0 2.8 3 0 0 3 3 3 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily UBA PF00627.26 AIO00022.1 - 0.056 13.2 0.7 0.19 11.5 0.1 2.2 2 0 0 2 2 2 0 UBA/TS-N domain PMEI PF04043.10 AIO00022.1 - 0.097 12.5 0.6 1.6 8.6 0.0 2.2 2 0 0 2 2 2 0 Plant invertase/pectin methylesterase inhibitor WD40 PF00400.27 AIO00024.1 - 3.5e-27 93.2 16.6 4.8e-06 26.2 0.0 6.8 7 0 0 7 7 7 6 WD domain, G-beta repeat Mpp10 PF04006.7 AIO00025.1 - 2.4e-58 197.9 37.4 2.7e-57 194.5 26.2 1.9 1 1 0 1 1 1 1 Mpp10 protein HSP90 PF00183.13 AIO00026.1 - 1.6e-146 488.8 8.0 2.1e-146 488.4 5.5 1.1 1 0 0 1 1 1 1 Hsp90 protein HATPase_c_3 PF13589.1 AIO00026.1 - 7.4e-10 38.6 0.0 1.9e-09 37.2 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 AIO00026.1 - 2.7e-05 23.8 0.0 6e-05 22.7 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase GSH-S_ATP PF02955.11 AIO00026.1 - 0.0038 16.3 0.0 0.19 10.8 0.0 2.4 2 0 0 2 2 2 1 Prokaryotic glutathione synthetase, ATP-grasp domain U-box PF04564.10 AIO00028.1 - 2.7e-12 46.4 0.0 3.1e-11 43.0 0.0 2.7 3 0 0 3 3 3 1 U-box domain zf-Nse PF11789.3 AIO00028.1 - 5.6e-05 22.5 0.0 0.00017 21.0 0.0 1.8 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit DUF2608 PF11019.3 AIO00028.1 - 0.055 12.4 0.0 0.1 11.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2608) Peptidase_C1 PF00112.18 AIO00033.1 - 5.7e-60 202.9 2.9 6.8e-60 202.6 2.0 1.1 1 0 0 1 1 1 1 Papain family cysteine protease Peptidase_C1_2 PF03051.10 AIO00033.1 - 3.8e-05 22.3 0.5 0.0021 16.6 0.1 2.1 2 0 0 2 2 2 2 Peptidase C1-like family Propeptide_C1 PF08127.8 AIO00033.1 - 0.0064 16.0 0.0 0.012 15.1 0.0 1.4 1 0 0 1 1 1 1 Peptidase family C1 propeptide Nop14 PF04147.7 AIO00034.1 - 1.9 6.3 8.7 2.4 5.9 6.0 1.0 1 0 0 1 1 1 0 Nop14-like family HMG_box PF00505.14 AIO00036.1 - 4.2e-32 110.2 10.6 3.9e-20 71.8 0.7 3.1 2 0 0 2 2 2 2 HMG (high mobility group) box HMG_box_2 PF09011.5 AIO00036.1 - 3.4e-22 78.5 20.3 2.3e-13 50.2 0.8 3.1 2 1 1 3 3 3 2 HMG-box domain DEK_C PF08766.6 AIO00036.1 - 4.3e-07 29.6 0.0 7.4e-07 28.8 0.0 1.4 1 0 0 1 1 1 1 DEK C terminal domain DUF1074 PF06382.6 AIO00036.1 - 0.00017 21.5 13.8 0.0062 16.5 1.4 2.2 1 1 1 2 2 2 2 Protein of unknown function (DUF1074) YABBY PF04690.8 AIO00036.1 - 0.00069 19.9 2.1 0.0013 19.0 1.5 1.5 1 0 0 1 1 1 1 YABBY protein HMG_box_5 PF14887.1 AIO00036.1 - 0.00083 19.0 18.0 0.0012 18.5 0.9 2.9 3 0 0 3 3 3 2 HMG (high mobility group) box 5 DUF736 PF05284.7 AIO00036.1 - 0.002 17.8 0.5 2 8.2 0.0 2.6 2 1 0 2 2 2 2 Protein of unknown function (DUF736) PDCD9 PF07147.7 AIO00036.1 - 0.0031 16.3 0.5 0.004 16.0 0.3 1.2 1 0 0 1 1 1 1 Mitochondrial 28S ribosomal protein S30 (PDCD9) DUF2582 PF10771.4 AIO00036.1 - 0.026 14.3 0.6 1.6 8.6 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2582) ApbA_C PF08546.6 AIO00036.1 - 0.064 13.2 0.0 0.12 12.3 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA C terminal RRM_5 PF13893.1 AIO00038.1 - 1.4e-09 37.6 0.1 1.8e-09 37.2 0.1 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 AIO00038.1 - 3.4e-07 30.1 0.0 4.6e-07 29.7 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 AIO00038.1 - 6.7e-07 28.8 0.0 1e-06 28.2 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Amidohydro_1 PF01979.15 AIO00039.1 - 3.7e-36 125.4 0.0 4.8e-36 125.0 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_5 PF13594.1 AIO00039.1 - 3.2e-09 36.4 0.0 1e-08 34.8 0.0 1.9 2 0 0 2 2 2 1 Amidohydrolase Amidohydro_4 PF13147.1 AIO00039.1 - 1.7e-07 31.5 0.2 0.001 19.1 0.0 2.3 2 0 0 2 2 2 2 Amidohydrolase Amidohydro_3 PF07969.6 AIO00039.1 - 0.0093 15.2 0.2 3.4 6.7 0.0 3.0 3 1 1 4 4 4 2 Amidohydrolase family Cyt-b5 PF00173.23 AIO00040.1 - 6.1e-10 38.7 0.0 1e-09 38.0 0.0 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Arf PF00025.16 AIO00042.1 - 5.4e-64 214.6 0.0 6e-64 214.4 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 AIO00042.1 - 1.2e-14 53.9 0.0 1.5e-14 53.6 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.17 AIO00042.1 - 1.2e-14 53.9 0.0 1.4e-14 53.7 0.0 1.0 1 0 0 1 1 1 1 Ras family G-alpha PF00503.15 AIO00042.1 - 1.1e-12 47.3 0.1 2.6e-09 36.2 0.0 2.3 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.7 AIO00042.1 - 5.4e-11 42.0 0.0 6.2e-11 41.8 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 AIO00042.1 - 2.3e-10 41.0 0.0 2.9e-10 40.6 0.0 1.1 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 AIO00042.1 - 2.3e-09 37.1 0.0 3.3e-09 36.7 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 AIO00042.1 - 3.6e-05 23.2 0.0 0.00021 20.8 0.0 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain cobW PF02492.14 AIO00042.1 - 0.0046 16.4 0.0 0.1 12.0 0.0 2.1 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain PduV-EutP PF10662.4 AIO00042.1 - 0.038 13.4 0.0 0.07 12.6 0.0 1.4 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_17 PF13207.1 AIO00042.1 - 0.066 14.0 0.0 0.091 13.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain Arch_ATPase PF01637.13 AIO00042.1 - 0.099 12.3 0.0 0.15 11.7 0.0 1.3 1 0 0 1 1 1 0 Archaeal ATPase AAA_16 PF13191.1 AIO00042.1 - 0.1 12.5 0.1 0.18 11.8 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain AAA_18 PF13238.1 AIO00042.1 - 0.13 12.5 0.0 0.2 11.9 0.0 1.4 1 1 0 1 1 1 0 AAA domain C1_1 PF00130.17 AIO00043.1 - 0.0011 18.6 6.7 0.0011 18.6 4.6 1.8 1 1 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) PhyH PF05721.8 AIO00043.1 - 0.0018 18.3 0.0 0.0065 16.5 0.0 2.2 2 1 0 2 2 2 1 Phytanoyl-CoA dioxygenase (PhyH) Prok-RING_1 PF14446.1 AIO00043.1 - 0.0085 15.8 7.1 0.0085 15.8 4.9 1.7 1 1 0 1 1 1 1 Prokaryotic RING finger family 1 PHD PF00628.24 AIO00043.1 - 0.021 14.5 10.0 0.042 13.5 6.9 1.6 1 0 0 1 1 1 0 PHD-finger OrfB_Zn_ribbon PF07282.6 AIO00043.1 - 2.5 7.8 9.5 0.2 11.3 2.5 2.1 2 0 0 2 2 2 0 Putative transposase DNA-binding domain DUF914 PF06027.7 AIO00044.1 - 6.3e-65 219.2 28.6 1.1e-48 165.8 5.3 2.1 2 0 0 2 2 2 2 Eukaryotic protein of unknown function (DUF914) EamA PF00892.15 AIO00044.1 - 1.5e-07 31.4 38.8 0.00017 21.6 8.8 2.6 2 1 0 2 2 2 2 EamA-like transporter family TPT PF03151.11 AIO00044.1 - 0.00033 20.3 28.1 0.013 15.1 6.9 2.3 2 0 0 2 2 2 2 Triose-phosphate Transporter family IPPT PF01715.12 AIO00045.1 - 6e-13 48.3 0.1 1.2e-12 47.4 0.0 1.4 2 0 0 2 2 2 1 IPP transferase zf-met PF12874.2 AIO00045.1 - 7.2e-07 29.1 0.3 1.3e-06 28.3 0.2 1.4 1 0 0 1 1 1 1 Zinc-finger of C2H2 type DUF3449 PF11931.3 AIO00045.1 - 0.00097 18.6 0.0 0.0015 18.0 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3449) zf-C2H2_jaz PF12171.3 AIO00045.1 - 0.0072 16.4 0.1 0.014 15.5 0.1 1.4 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding AKAP95 PF04988.7 AIO00045.1 - 0.029 14.1 0.1 0.056 13.2 0.0 1.3 1 0 0 1 1 1 0 A-kinase anchoring protein 95 (AKAP95) DUF829 PF05705.9 AIO00045.1 - 0.03 14.0 0.0 1.3 8.6 0.0 2.1 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF829) Peptidase_A22B PF04258.8 AIO00046.1 - 7.4e-56 189.7 15.6 4.6e-54 183.9 9.4 2.0 1 1 1 2 2 2 2 Signal peptide peptidase DUF1119 PF06550.6 AIO00046.1 - 0.073 12.1 14.4 0.52 9.3 10.0 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF1119) LETM1 PF07766.8 AIO00047.1 - 4.5e-39 134.0 3.8 2.5e-38 131.6 0.9 2.7 2 1 0 2 2 2 1 LETM1-like protein Dpoe2NT PF12213.3 AIO00047.1 - 0.038 13.9 0.4 0.12 12.2 0.0 2.1 2 0 0 2 2 2 0 DNA polymerases epsilon N terminal Pex16 PF08610.5 AIO00048.1 - 0.08 11.9 0.0 0.13 11.2 0.0 1.2 1 0 0 1 1 1 0 Peroxisomal membrane protein (Pex16) PIRT PF15099.1 AIO00048.1 - 0.097 11.8 5.8 0.042 13.0 0.4 2.7 3 0 0 3 3 3 0 Phosphoinositide-interacting protein family Methyltransf_25 PF13649.1 AIO00050.1 - 3.5e-21 75.4 0.0 7.3e-21 74.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain FGE-sulfatase PF03781.11 AIO00050.1 - 2.6e-20 72.8 0.4 5.8e-20 71.7 0.3 1.6 1 1 0 1 1 1 1 Sulfatase-modifying factor enzyme 1 DinB_2 PF12867.2 AIO00050.1 - 7.8e-07 29.4 0.0 1.7e-06 28.3 0.0 1.7 1 0 0 1 1 1 1 DinB superfamily Methyltransf_18 PF12847.2 AIO00050.1 - 1.2e-05 25.8 0.0 4.3e-05 24.0 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 AIO00050.1 - 0.002 17.8 0.2 0.0099 15.6 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 AIO00050.1 - 0.0021 17.6 0.0 0.039 13.5 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 AIO00050.1 - 0.0043 17.5 0.0 0.017 15.6 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 AIO00050.1 - 0.026 14.9 0.0 0.085 13.3 0.0 1.9 1 1 0 1 1 1 0 Methyltransferase domain Kinesin PF00225.18 AIO00053.1 - 1.3e-83 280.5 0.0 1.3e-83 280.5 0.0 3.1 2 1 0 2 2 2 1 Kinesin motor domain DUF4645 PF15488.1 AIO00053.1 - 1.1 8.3 4.1 2.9 6.9 2.8 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4645) Reo_sigmaC PF04582.7 AIO00056.1 - 1.3e-05 24.5 4.0 0.13 11.4 0.0 2.6 3 0 0 3 3 3 2 Reovirus sigma C capsid protein Baculo_PEP_C PF04513.7 AIO00056.1 - 0.00013 21.7 1.5 0.88 9.3 0.5 3.1 3 0 0 3 3 3 2 Baculovirus polyhedron envelope protein, PEP, C terminus TBPIP PF07106.8 AIO00056.1 - 0.0059 16.1 2.2 0.0059 16.1 1.5 3.2 3 0 0 3 3 3 1 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Spc7 PF08317.6 AIO00056.1 - 0.0063 15.2 2.7 0.0063 15.2 1.9 2.9 3 0 0 3 3 3 1 Spc7 kinetochore protein Phage_GP20 PF06810.6 AIO00056.1 - 0.012 15.0 3.3 0.012 15.0 2.3 2.7 3 0 0 3 3 3 0 Phage minor structural protein GP20 BLOC1_2 PF10046.4 AIO00056.1 - 0.016 15.3 0.6 0.016 15.3 0.4 2.7 3 0 0 3 3 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Mto2_bdg PF12808.2 AIO00056.1 - 0.026 14.6 8.1 0.21 11.7 0.3 3.5 3 0 0 3 3 2 0 Micro-tubular organiser Mto1 C-term Mto2-binding region WHEP-TRS PF00458.15 AIO00056.1 - 0.067 12.8 0.6 0.17 11.6 0.4 1.6 1 0 0 1 1 1 0 WHEP-TRS domain DUF972 PF06156.8 AIO00056.1 - 0.081 13.2 0.2 0.081 13.2 0.1 4.4 4 1 1 5 5 4 0 Protein of unknown function (DUF972) Tropomyosin_1 PF12718.2 AIO00056.1 - 0.12 12.2 17.3 5.1 6.9 0.1 4.3 3 1 1 4 4 4 0 Tropomyosin like Arfaptin PF06456.8 AIO00056.1 - 0.16 11.3 7.1 0.1 11.9 0.9 2.5 2 0 0 2 2 2 0 Arfaptin-like domain HALZ PF02183.13 AIO00056.1 - 0.19 11.4 0.1 0.19 11.4 0.0 3.9 5 0 0 5 5 4 0 Homeobox associated leucine zipper TMF_TATA_bd PF12325.3 AIO00056.1 - 0.45 10.2 15.4 0.041 13.6 1.1 3.1 3 1 0 3 3 3 0 TATA element modulatory factor 1 TATA binding Herpes_U30 PF04523.8 AIO00056.1 - 0.51 7.7 5.4 0.04 11.3 0.4 1.5 2 0 0 2 2 2 0 Herpes virus tegument protein U30 DUF904 PF06005.7 AIO00056.1 - 0.79 10.0 14.5 4.1 7.7 1.4 3.7 3 0 0 3 3 3 0 Protein of unknown function (DUF904) DASH_Dad2 PF08654.5 AIO00056.1 - 2.7 8.0 8.1 0.37 10.8 0.9 2.9 3 0 0 3 3 3 0 DASH complex subunit Dad2 XhlA PF10779.4 AIO00056.1 - 3.3 7.6 8.2 8.8 6.3 0.0 4.0 3 1 0 3 3 3 0 Haemolysin XhlA bZIP_1 PF00170.16 AIO00056.1 - 3.4 7.6 9.8 0.55 10.2 0.1 3.6 3 2 1 4 4 3 0 bZIP transcription factor bZIP_2 PF07716.10 AIO00056.1 - 3.8 7.4 10.9 0.79 9.5 0.1 4.5 5 0 0 5 5 5 0 Basic region leucine zipper DUF342 PF03961.8 AIO00056.1 - 5.9 5.1 8.5 0.16 10.3 0.9 1.9 3 0 0 3 3 3 0 Protein of unknown function (DUF342) Seryl_tRNA_N PF02403.17 AIO00056.1 - 6.4 6.8 16.5 0.35 10.9 2.0 4.1 3 2 1 4 4 4 0 Seryl-tRNA synthetase N-terminal domain Atg14 PF10186.4 AIO00056.1 - 8.6 5.2 19.1 0.011 14.7 2.8 2.8 3 0 0 3 3 3 0 UV radiation resistance protein and autophagy-related subunit 14 ADH_N PF08240.7 AIO00057.1 - 7.5e-13 48.1 2.4 2.7e-12 46.4 0.1 2.4 2 1 1 3 3 3 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 AIO00057.1 - 3.2e-12 47.4 0.0 1.1e-11 45.7 0.0 1.9 2 1 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.21 AIO00057.1 - 2.7e-11 43.1 0.0 6.8e-10 38.5 0.0 2.3 2 0 0 2 2 2 1 Zinc-binding dehydrogenase SseB PF07179.7 AIO00058.1 - 0.00064 19.5 0.0 1.3 8.9 0.0 2.5 2 0 0 2 2 2 2 SseB protein N-terminal domain LMBR1 PF04791.11 AIO00059.1 - 0.79 8.2 4.9 0.86 8.1 3.4 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein cNMP_binding PF00027.24 AIO00060.1 - 1.8e-14 53.3 0.0 1.5e-09 37.5 0.0 3.8 3 0 0 3 3 3 3 Cyclic nucleotide-binding domain Ku PF02735.11 AIO00061.1 - 4.5e-19 68.6 0.0 9.4e-19 67.5 0.0 1.5 2 0 0 2 2 2 1 Ku70/Ku80 beta-barrel domain Ku_N PF03731.10 AIO00061.1 - 6e-15 55.2 0.0 3.9e-10 39.5 0.0 2.6 3 0 0 3 3 3 2 Ku70/Ku80 N-terminal alpha/beta domain HeH PF12949.2 AIO00061.1 - 0.02 14.4 0.0 0.05 13.1 0.0 1.6 1 0 0 1 1 1 0 HeH/LEM domain Ku_C PF03730.9 AIO00061.1 - 0.023 15.2 0.0 0.18 12.3 0.0 2.2 2 0 0 2 2 2 0 Ku70/Ku80 C-terminal arm SAP PF02037.22 AIO00061.1 - 0.049 13.1 0.0 0.11 11.9 0.0 1.7 1 0 0 1 1 1 0 SAP domain Phytoreo_Pns PF05451.6 AIO00061.1 - 0.28 9.7 0.0 0.46 9.0 0.0 1.2 1 0 0 1 1 1 0 Phytoreovirus nonstructural protein Pns10/11 Ribosomal_L4 PF00573.17 AIO00063.1 - 2.7e-39 134.5 0.1 4.2e-39 133.9 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family Ribos_L4_asso_C PF14374.1 AIO00063.1 - 8.2e-15 54.4 7.2 1.2e-14 53.9 3.6 2.2 2 0 0 2 2 2 1 60S ribosomal protein L4 C-terminal domain Ank_2 PF12796.2 AIO00064.1 - 4e-32 110.4 1.6 2e-10 40.8 0.1 4.4 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 AIO00064.1 - 3e-27 93.0 1.5 7e-06 25.5 0.0 6.8 7 0 0 7 7 7 5 Ankyrin repeat Ank_4 PF13637.1 AIO00064.1 - 2.3e-24 85.2 0.1 2.1e-10 40.8 0.0 4.5 3 1 1 4 4 4 4 Ankyrin repeats (many copies) Ank_5 PF13857.1 AIO00064.1 - 2.7e-22 78.2 1.3 7.4e-06 26.0 0.0 6.2 2 2 4 6 6 6 6 Ankyrin repeats (many copies) Ank_3 PF13606.1 AIO00064.1 - 3.1e-22 76.4 0.8 0.0043 17.1 0.0 6.7 7 0 0 7 7 7 6 Ankyrin repeat zf-HC2 PF13490.1 AIO00064.1 - 1.2 9.1 3.7 1.3 9.0 0.1 2.8 3 0 0 3 3 3 0 Putative zinc-finger PSP1 PF04468.7 AIO00066.1 - 1.3e-10 41.0 0.1 2.4e-10 40.2 0.0 1.4 1 0 0 1 1 1 1 PSP1 C-terminal conserved region Thioredoxin_8 PF13905.1 AIO00067.1 - 5.9e-10 39.1 0.0 1e-09 38.3 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin-like Redoxin PF08534.5 AIO00067.1 - 0.022 14.3 0.0 0.035 13.6 0.0 1.3 1 0 0 1 1 1 0 Redoxin DUF221 PF02714.10 AIO00067.1 - 0.059 12.2 0.2 0.091 11.5 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function DUF221 Thioredoxin_8 PF13905.1 AIO00068.1 - 8e-22 77.1 0.0 4.2e-17 62.0 0.0 2.3 2 0 0 2 2 2 2 Thioredoxin-like AhpC-TSA PF00578.16 AIO00068.1 - 2.7e-12 46.4 0.0 5.4e-12 45.4 0.0 1.4 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 AIO00068.1 - 1e-11 44.5 0.0 2.3e-11 43.4 0.0 1.5 2 0 0 2 2 2 1 Redoxin Thioredoxin PF00085.15 AIO00068.1 - 1e-07 31.5 0.0 3.3e-07 29.9 0.0 1.8 2 0 0 2 2 2 1 Thioredoxin Thioredoxin_2 PF13098.1 AIO00068.1 - 1.7e-06 28.1 0.0 3.8e-06 27.0 0.0 1.6 1 1 0 1 1 1 1 Thioredoxin-like domain TraF PF13728.1 AIO00068.1 - 6e-05 22.6 0.0 9.1e-05 22.0 0.0 1.2 1 0 0 1 1 1 1 F plasmid transfer operon protein Thioredoxin_7 PF13899.1 AIO00068.1 - 0.00013 21.8 0.0 0.0003 20.7 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_9 PF14595.1 AIO00068.1 - 0.00016 21.2 0.0 0.00044 19.8 0.0 1.6 2 0 0 2 2 2 1 Thioredoxin Thioredoxin_8 PF13905.1 AIO00069.1 - 1.1e-23 83.0 0.0 1.5e-23 82.7 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin-like AhpC-TSA PF00578.16 AIO00069.1 - 1.1e-07 31.5 0.0 1.4e-07 31.2 0.0 1.3 1 1 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 AIO00069.1 - 2.4e-06 27.1 0.0 2.6e-06 27.0 0.0 1.1 1 0 0 1 1 1 1 Redoxin Thioredoxin PF00085.15 AIO00069.1 - 3.1e-06 26.7 0.2 3.6e-05 23.3 0.1 2.0 1 1 1 2 2 2 1 Thioredoxin Thioredoxin_2 PF13098.1 AIO00069.1 - 3.8e-06 27.0 0.0 5.3e-06 26.5 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin-like domain TraF PF13728.1 AIO00069.1 - 0.0009 18.7 0.0 0.0027 17.2 0.0 1.7 1 1 0 1 1 1 1 F plasmid transfer operon protein Thioredoxin_7 PF13899.1 AIO00069.1 - 0.0042 17.0 0.0 0.007 16.3 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_9 PF14595.1 AIO00069.1 - 0.0069 15.9 0.0 0.064 12.8 0.0 2.0 2 0 0 2 2 2 1 Thioredoxin DUF953 PF06110.6 AIO00069.1 - 0.014 14.8 0.2 0.39 10.1 0.1 2.2 1 1 0 1 1 1 0 Eukaryotic protein of unknown function (DUF953) Thioredoxin_8 PF13905.1 AIO00070.1 - 2.6e-24 85.1 0.0 3.9e-24 84.5 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin-like AhpC-TSA PF00578.16 AIO00070.1 - 3e-09 36.6 0.1 3.3e-09 36.4 0.0 1.3 1 1 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 AIO00070.1 - 6.6e-09 35.4 0.1 9.2e-09 34.9 0.0 1.2 1 1 0 1 1 1 1 Redoxin Thioredoxin PF00085.15 AIO00070.1 - 1.5e-08 34.2 0.0 1.6e-07 30.9 0.0 2.0 2 0 0 2 2 2 1 Thioredoxin Thioredoxin_2 PF13098.1 AIO00070.1 - 9.4e-06 25.7 0.0 1.3e-05 25.3 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin-like domain TraF PF13728.1 AIO00070.1 - 5.8e-05 22.6 0.0 0.00012 21.6 0.0 1.4 2 0 0 2 2 2 1 F plasmid transfer operon protein Thioredoxin_7 PF13899.1 AIO00070.1 - 0.00035 20.5 0.0 0.00063 19.7 0.0 1.4 1 1 0 1 1 1 1 Thioredoxin-like Thioredoxin_9 PF14595.1 AIO00070.1 - 0.00077 19.0 0.0 0.0013 18.2 0.0 1.5 1 1 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.1 AIO00071.1 - 2.6e-24 85.1 0.0 3.9e-24 84.5 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin-like AhpC-TSA PF00578.16 AIO00071.1 - 3.2e-09 36.5 0.1 4e-09 36.2 0.0 1.3 1 1 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 AIO00071.1 - 6.7e-09 35.4 0.1 7.4e-09 35.3 0.0 1.2 1 1 0 1 1 1 1 Redoxin Thioredoxin PF00085.15 AIO00071.1 - 1.1e-08 34.6 0.0 1.6e-07 30.9 0.0 2.0 2 0 0 2 2 2 1 Thioredoxin Thioredoxin_2 PF13098.1 AIO00071.1 - 6.7e-06 26.2 0.0 9.6e-06 25.7 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin-like domain TraF PF13728.1 AIO00071.1 - 5.7e-05 22.7 0.0 8.7e-05 22.0 0.0 1.4 1 1 0 1 1 1 1 F plasmid transfer operon protein Thioredoxin_7 PF13899.1 AIO00071.1 - 0.00037 20.4 0.0 0.00063 19.7 0.0 1.4 1 1 0 1 1 1 1 Thioredoxin-like Thioredoxin_9 PF14595.1 AIO00071.1 - 0.00066 19.2 0.0 0.0012 18.3 0.0 1.6 1 1 0 1 1 1 1 Thioredoxin EF-hand_1 PF00036.27 AIO00072.1 - 1.5e-05 23.9 0.0 4.5e-05 22.4 0.0 1.8 2 0 0 2 2 2 1 EF hand EF-hand_8 PF13833.1 AIO00072.1 - 0.00058 19.4 0.0 0.0012 18.4 0.0 1.5 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.1 AIO00072.1 - 0.0012 18.5 0.0 0.0031 17.2 0.0 1.7 1 0 0 1 1 1 1 EF-hand domain EF-hand_7 PF13499.1 AIO00072.1 - 0.0013 18.7 0.0 0.0054 16.8 0.0 2.0 2 0 0 2 2 2 1 EF-hand domain pair SPT16 PF08644.6 AIO00072.1 - 0.0082 15.9 0.0 0.015 15.1 0.0 1.4 1 0 0 1 1 1 1 FACT complex subunit (SPT16/CDC68) G-gamma PF00631.17 AIO00072.1 - 0.083 12.6 0.0 0.97 9.2 0.0 2.2 2 0 0 2 2 2 0 GGL domain Thioredoxin_8 PF13905.1 AIO00073.1 - 1.9e-06 27.9 0.0 0.023 14.7 0.0 3.3 3 0 0 3 3 3 3 Thioredoxin-like PIG-L PF02585.12 AIO00076.1 - 0.11 12.9 0.1 0.87 10.0 0.0 2.2 2 0 0 2 2 2 0 GlcNAc-PI de-N-acetylase DUF572 PF04502.8 AIO00077.1 - 9.7e-16 57.8 16.0 5.3e-15 55.4 11.1 1.9 1 1 0 1 1 1 1 Family of unknown function (DUF572) DUF2570 PF10828.3 AIO00077.1 - 0.6 9.7 5.7 1 9.0 0.9 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2570) Sec16_C PF12931.2 AIO00078.1 - 2.5e-10 40.5 0.0 4.2e-10 39.8 0.0 1.3 1 0 0 1 1 1 1 Sec23-binding domain of Sec16 HSP70 PF00012.15 AIO00079.1 - 1e-25 89.7 8.7 7.4e-25 86.9 0.1 2.6 1 1 1 2 2 2 2 Hsp70 protein TPR_11 PF13414.1 AIO00079.1 - 4.6e-17 61.4 2.9 1.4e-10 40.6 0.4 3.0 2 1 1 3 3 2 2 TPR repeat TPR_1 PF00515.23 AIO00079.1 - 3.9e-10 38.8 0.2 6e-06 25.6 0.1 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.12 AIO00079.1 - 9e-10 37.7 0.9 6.8e-05 22.4 0.2 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.1 AIO00079.1 - 8.9e-08 31.9 0.4 3.2e-05 23.7 0.1 3.2 2 1 1 3 3 3 2 Tetratricopeptide repeat Apc3 PF12895.2 AIO00079.1 - 2.6e-06 27.4 4.2 0.00034 20.6 0.5 2.0 1 1 1 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.1 AIO00079.1 - 3.3e-06 26.4 0.0 0.0015 18.1 0.0 3.1 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.1 AIO00079.1 - 2e-05 24.0 0.0 0.22 11.4 0.0 3.2 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.1 AIO00079.1 - 3.1e-05 24.5 0.1 0.00018 22.0 0.0 2.5 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_19 PF14559.1 AIO00079.1 - 4.3e-05 23.7 0.2 0.00068 19.9 0.1 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_9 PF13371.1 AIO00079.1 - 9.4e-05 22.1 2.4 0.00033 20.4 0.0 2.8 3 0 0 3 3 2 1 Tetratricopeptide repeat TPR_17 PF13431.1 AIO00079.1 - 0.0012 18.8 0.0 0.0048 17.0 0.0 2.1 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_14 PF13428.1 AIO00079.1 - 0.0058 17.1 0.1 0.053 14.1 0.0 2.8 1 0 0 1 1 1 1 Tetratricopeptide repeat Apc5 PF12862.2 AIO00079.1 - 0.0085 15.9 1.1 0.18 11.6 0.1 3.2 2 1 0 2 2 2 1 Anaphase-promoting complex subunit 5 CMV_1a PF12467.3 AIO00079.1 - 0.031 14.6 0.4 0.031 14.6 0.3 3.2 4 0 0 4 4 4 0 Cucumber mosaic virus 1a protein family TPR_6 PF13174.1 AIO00079.1 - 0.037 14.4 1.1 1.6 9.3 1.0 3.5 3 0 0 3 3 2 0 Tetratricopeptide repeat AAA_2 PF07724.9 AIO00081.1 - 2.2e-55 187.2 0.0 5.1e-53 179.4 0.0 3.4 3 0 0 3 3 3 1 AAA domain (Cdc48 subfamily) AAA PF00004.24 AIO00081.1 - 6.3e-27 94.3 0.0 5.1e-15 55.8 0.0 3.1 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.4 AIO00081.1 - 6.5e-21 74.0 0.1 6.5e-21 74.0 0.1 3.2 3 0 0 3 3 2 1 C-terminal, D2-small domain, of ClpB protein AAA_5 PF07728.9 AIO00081.1 - 3.2e-15 56.0 0.3 1.9e-10 40.6 0.0 3.6 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 AIO00081.1 - 1.4e-11 44.7 10.7 0.0013 18.7 0.0 5.6 4 3 1 6 6 6 3 AAA ATPase domain Clp_N PF02861.15 AIO00081.1 - 1.8e-10 40.5 4.1 9.4e-05 22.2 1.0 3.1 2 0 0 2 2 2 2 Clp amino terminal domain AAA_22 PF13401.1 AIO00081.1 - 2.9e-09 37.1 1.9 0.0024 18.0 0.0 4.7 2 2 1 4 4 4 2 AAA domain AAA_14 PF13173.1 AIO00081.1 - 3.5e-08 33.4 0.0 0.0064 16.3 0.0 3.4 2 0 0 2 2 2 2 AAA domain Sigma54_activat PF00158.21 AIO00081.1 - 1.1e-07 31.4 0.0 5.9e-05 22.5 0.0 3.0 2 1 0 2 2 2 1 Sigma-54 interaction domain AAA_17 PF13207.1 AIO00081.1 - 2.6e-07 31.5 2.6 0.012 16.4 0.0 3.8 2 1 0 2 2 2 2 AAA domain IstB_IS21 PF01695.12 AIO00081.1 - 3.2e-07 29.9 0.0 0.016 14.6 0.0 2.7 2 0 0 2 2 2 2 IstB-like ATP binding protein Zeta_toxin PF06414.7 AIO00081.1 - 5.5e-06 25.6 0.3 0.0017 17.5 0.0 3.8 5 0 0 5 5 4 1 Zeta toxin AAA_19 PF13245.1 AIO00081.1 - 7.5e-06 25.6 0.2 0.12 12.1 0.0 3.3 2 1 1 3 3 3 2 Part of AAA domain RuvB_N PF05496.7 AIO00081.1 - 1.5e-05 24.1 0.4 0.22 10.5 0.0 3.9 4 0 0 4 4 4 1 Holliday junction DNA helicase ruvB N-terminus AAA_18 PF13238.1 AIO00081.1 - 4.1e-05 23.8 2.4 0.43 10.8 0.0 4.6 3 1 2 5 5 5 2 AAA domain Arch_ATPase PF01637.13 AIO00081.1 - 0.00012 21.8 8.8 1 9.0 0.1 4.3 3 3 1 4 4 3 2 Archaeal ATPase AAA_25 PF13481.1 AIO00081.1 - 0.00018 20.9 0.8 2.3 7.5 0.0 4.2 3 1 1 4 4 4 2 AAA domain NACHT PF05729.7 AIO00081.1 - 0.00037 20.2 0.0 0.083 12.5 0.0 3.3 3 1 0 3 3 3 1 NACHT domain ResIII PF04851.10 AIO00081.1 - 0.00058 19.7 0.7 0.16 11.7 0.0 4.0 3 1 1 4 4 4 1 Type III restriction enzyme, res subunit Mg_chelatase PF01078.16 AIO00081.1 - 0.001 18.2 0.1 9.4 5.3 0.0 3.7 2 1 0 3 3 3 0 Magnesium chelatase, subunit ChlI DUF815 PF05673.8 AIO00081.1 - 0.0011 18.0 0.1 0.24 10.3 0.1 2.9 2 1 0 2 2 2 1 Protein of unknown function (DUF815) RNA_helicase PF00910.17 AIO00081.1 - 0.0014 18.8 0.0 1.6 8.9 0.0 2.9 2 0 0 2 2 2 1 RNA helicase AAA_33 PF13671.1 AIO00081.1 - 0.0016 18.3 0.2 0.55 10.1 0.0 3.7 4 0 0 4 4 4 1 AAA domain AAA_10 PF12846.2 AIO00081.1 - 0.0018 17.7 0.6 3.8 6.8 0.0 4.1 2 2 1 4 4 4 1 AAA-like domain AAA_3 PF07726.6 AIO00081.1 - 0.0035 16.9 0.0 2.4 7.7 0.0 3.5 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.1 AIO00081.1 - 0.0061 16.0 0.0 4 7.0 0.0 2.7 2 0 0 2 2 2 0 P-loop containing region of AAA domain NTPase_1 PF03266.10 AIO00081.1 - 0.0068 16.1 0.2 3.1 7.4 0.0 3.4 3 0 0 3 3 3 1 NTPase DUF258 PF03193.11 AIO00081.1 - 0.0095 15.1 0.0 3.2 6.9 0.0 2.8 3 0 0 3 3 2 1 Protein of unknown function, DUF258 ABC_tran PF00005.22 AIO00081.1 - 0.0098 16.1 1.4 13 6.0 0.0 3.9 4 0 0 4 4 3 0 ABC transporter AAA_28 PF13521.1 AIO00081.1 - 0.01 15.8 0.0 5.1 7.0 0.0 3.3 3 0 0 3 3 2 0 AAA domain MMR_HSR1 PF01926.18 AIO00081.1 - 0.04 13.8 0.0 1.2 9.1 0.0 2.9 2 0 0 2 2 2 0 50S ribosome-binding GTPase MobB PF03205.9 AIO00081.1 - 0.048 13.3 0.0 5.2 6.7 0.0 2.7 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B Miro PF08477.8 AIO00081.1 - 0.075 13.5 0.0 2.5 8.6 0.0 3.0 3 0 0 3 3 2 0 Miro-like protein UPF0079 PF02367.12 AIO00081.1 - 0.075 12.6 0.0 18 4.9 0.0 2.7 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 DUF4524 PF15025.1 AIO00081.1 - 0.12 11.8 0.0 0.25 10.8 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4524) AAA_23 PF13476.1 AIO00081.1 - 0.22 11.8 16.2 6.2 7.0 0.0 3.8 3 1 0 3 3 2 0 AAA domain V_ATPase_I PF01496.14 AIO00081.1 - 3.5 5.3 5.1 5.3 4.7 3.5 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family IncA PF04156.9 AIO00081.1 - 5 6.6 11.1 8.9 5.8 6.5 2.2 2 0 0 2 2 2 0 IncA protein APG6 PF04111.7 AIO00081.1 - 6.4 5.7 9.7 12 4.7 6.8 1.4 1 0 0 1 1 1 0 Autophagy protein Apg6 Lipase_3 PF01764.20 AIO00082.1 - 7.8e-28 96.8 0.0 1.6e-27 95.8 0.0 1.5 1 0 0 1 1 1 1 Lipase (class 3) MIG-14_Wnt-bd PF06664.7 AIO00082.1 - 5.8e-07 28.6 8.8 5.8e-07 28.6 6.1 2.2 2 0 0 2 2 2 2 Wnt-binding factor required for Wnt secretion GvpG PF05120.7 AIO00082.1 - 0.4 10.5 0.0 0.75 9.6 0.0 1.4 1 0 0 1 1 1 0 Gas vesicle protein G DSS1_SEM1 PF05160.8 AIO00083.1 - 0.00052 19.7 2.5 0.00052 19.7 1.7 1.8 2 0 0 2 2 2 1 DSS1/SEM1 family Tnp_P_element_C PF12596.3 AIO00083.1 - 0.056 13.7 0.3 0.097 13.0 0.1 1.6 1 1 1 2 2 2 0 87kDa Transposase DUF4034 PF13226.1 AIO00084.1 - 0.018 14.1 0.0 0.029 13.4 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4034) Carn_acyltransf PF00755.15 AIO00085.1 - 9.6e-91 304.6 0.0 1.1e-90 304.4 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase RNA_pol_Rpc34 PF05158.7 AIO00086.1 - 9.3e-51 172.9 0.0 5.5e-50 170.4 0.0 2.1 1 1 0 1 1 1 1 RNA polymerase Rpc34 subunit TFIIE_alpha PF02002.12 AIO00086.1 - 0.055 12.9 0.0 0.1 12.1 0.0 1.3 1 0 0 1 1 1 0 TFIIE alpha subunit Pkinase PF00069.20 AIO00087.1 - 1.6e-61 207.7 0.0 3.3e-61 206.7 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AIO00087.1 - 9.1e-33 113.4 0.0 4.9e-23 81.5 0.0 2.9 3 0 0 3 3 3 2 Protein tyrosine kinase Kdo PF06293.9 AIO00087.1 - 0.0059 15.6 0.0 0.011 14.7 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 AIO00087.1 - 0.077 11.9 0.0 1.1 8.1 0.0 2.3 1 1 0 1 1 1 0 Kinase-like RRM_1 PF00076.17 AIO00088.1 - 5.5e-32 109.2 0.0 1.2e-19 69.6 0.0 3.3 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 AIO00088.1 - 1.3e-24 85.9 0.0 2e-13 50.0 0.0 3.0 2 1 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 AIO00088.1 - 1e-17 63.7 0.0 1.4e-12 47.2 0.0 3.2 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 AIO00088.1 - 0.0026 17.4 0.0 0.037 13.7 0.0 2.7 1 1 2 3 3 3 1 Limkain b1 Calcipressin PF04847.7 AIO00088.1 - 0.0099 15.4 0.0 0.052 13.1 0.0 2.0 2 0 0 2 2 2 1 Calcipressin RRM_3 PF08777.6 AIO00088.1 - 0.024 14.5 0.0 7.2 6.5 0.0 2.7 2 1 0 2 2 2 0 RNA binding motif Amastin PF07344.6 AIO00089.1 - 5.7e-43 146.2 13.1 6.6e-43 146.0 9.1 1.0 1 0 0 1 1 1 1 Amastin surface glycoprotein PMP22_Claudin PF00822.15 AIO00089.1 - 0.054 13.1 12.1 0.07 12.7 8.3 1.3 1 1 0 1 1 1 0 PMP-22/EMP/MP20/Claudin family Claudin_2 PF13903.1 AIO00089.1 - 0.75 9.4 18.9 0.063 12.9 9.1 1.8 1 1 1 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction RRM_1 PF00076.17 AIO00090.1 - 2.8e-22 78.1 0.0 2.2e-11 43.2 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 AIO00090.1 - 7.3e-15 54.7 0.0 2.4e-07 30.6 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 AIO00090.1 - 5.2e-05 23.0 0.0 0.0015 18.3 0.0 2.3 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 AIO00091.1 - 9.7e-25 86.0 0.0 8.7e-13 47.7 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 AIO00091.1 - 3.7e-16 58.8 0.1 7.6e-09 35.4 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 AIO00091.1 - 1.2e-08 34.6 0.0 6e-07 29.2 0.0 2.4 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 AIO00091.1 - 0.03 14.0 0.4 0.25 11.1 0.1 2.5 2 1 1 3 3 3 0 Limkain b1 RRM_1 PF00076.17 AIO00092.1 - 9.9e-26 89.1 0.1 5e-14 51.6 0.0 3.4 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 AIO00092.1 - 4.9e-21 74.4 0.5 2.5e-10 40.1 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 AIO00092.1 - 8.1e-09 35.2 0.0 9.6e-05 22.1 0.0 3.6 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 AIO00092.1 - 0.16 11.7 0.1 0.33 10.7 0.0 1.6 1 0 0 1 1 1 0 Limkain b1 Nab6_mRNP_bdg PF10567.4 AIO00092.1 - 0.45 9.4 0.0 0.77 8.6 0.0 1.3 1 0 0 1 1 1 0 RNA-recognition motif RRM_1 PF00076.17 AIO00094.1 - 3.2e-20 71.5 0.1 9.9e-13 47.5 0.1 3.8 4 0 0 4 4 4 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 AIO00094.1 - 3.7e-16 58.8 0.5 2.6e-09 36.9 0.0 3.4 3 0 0 3 3 3 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) zf-LYAR PF08790.6 AIO00095.1 - 5.2e-14 51.6 3.8 5.2e-14 51.6 2.7 2.1 2 0 0 2 2 2 1 LYAR-type C2HC zinc finger zf-DNL PF05180.7 AIO00095.1 - 0.83 9.4 6.6 1.4 8.6 4.5 1.4 1 0 0 1 1 1 0 DNL zinc finger Clat_adaptor_s PF01217.15 AIO00098.1 - 9.9e-51 171.1 1.0 1.2e-50 170.9 0.7 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain PI3_PI4_kinase PF00454.22 AIO00099.1 - 5.3e-31 107.8 0.1 1.1e-29 103.5 0.0 2.4 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.15 AIO00099.1 - 6.6e-15 54.7 0.1 1.3e-14 53.8 0.1 1.4 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) DHHW PF14286.1 AIO00100.1 - 0.7 9.1 3.4 14 4.8 1.3 2.1 2 0 0 2 2 2 0 DHHW protein Ank_4 PF13637.1 AIO00101.1 - 2.8e-05 24.5 0.2 0.00012 22.4 0.1 2.1 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.2 AIO00101.1 - 5e-05 23.5 0.1 0.0001 22.5 0.1 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 AIO00101.1 - 0.00025 20.6 0.3 0.13 12.1 0.1 2.7 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.1 AIO00101.1 - 0.0011 19.0 0.2 0.032 14.4 0.0 2.7 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 AIO00101.1 - 0.0017 18.3 0.2 0.23 11.7 0.0 2.7 2 0 0 2 2 2 1 Ankyrin repeat DUF533 PF04391.7 AIO00101.1 - 0.0073 15.7 2.3 0.0098 15.2 0.5 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF533) Asn_synthase PF00733.16 AIO00102.1 - 4.8e-34 117.9 0.6 5.1e-18 65.4 0.2 3.3 2 1 0 3 3 3 3 Asparagine synthase SelP_N PF04592.9 AIO00102.1 - 0.04 13.3 1.6 0.075 12.3 1.1 1.4 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Nodulin-like PF06813.8 AIO00103.1 - 1.5e-10 40.7 11.4 1.5e-10 40.7 7.9 2.5 2 1 0 2 2 2 1 Nodulin-like MFS_1 PF07690.11 AIO00104.1 - 6.9e-15 54.6 42.0 9.2e-13 47.6 15.4 2.7 2 1 0 2 2 2 2 Major Facilitator Superfamily Nodulin-like PF06813.8 AIO00104.1 - 1.1e-11 44.5 18.8 1.1e-11 44.5 13.1 2.4 2 1 0 2 2 2 1 Nodulin-like MFS_1 PF07690.11 AIO00105.1 - 1.3e-19 70.0 33.0 5.3e-14 51.6 15.3 2.4 2 0 0 2 2 2 2 Major Facilitator Superfamily Nodulin-like PF06813.8 AIO00105.1 - 9.1e-12 44.7 19.3 9.1e-12 44.7 13.4 2.5 2 1 0 2 2 2 1 Nodulin-like DC_STAMP PF07782.8 AIO00107.1 - 0.06 12.9 0.0 0.09 12.3 0.0 1.3 1 0 0 1 1 1 0 DC-STAMP-like protein Toxin_32 PF08120.6 AIO00108.1 - 0.46 10.1 4.4 6.5 6.4 0.4 2.3 2 0 0 2 2 2 0 Tamulustoxin family RabGAP-TBC PF00566.13 AIO00109.1 - 1.8e-43 148.4 0.0 2.6e-43 147.9 0.0 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain LisH PF08513.6 AIO00109.1 - 0.071 12.9 0.0 0.25 11.1 0.0 2.0 1 0 0 1 1 1 0 LisH Peptidase_M20 PF01546.23 AIO00110.1 - 7.6e-36 123.3 0.0 1.1e-35 122.8 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 AIO00110.1 - 6.9e-19 67.6 0.0 1.1e-18 67.0 0.0 1.3 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M42 PF05343.9 AIO00110.1 - 0.13 10.9 0.0 2.6 6.7 0.0 2.5 2 1 1 3 3 3 0 M42 glutamyl aminopeptidase WD40 PF00400.27 AIO00111.1 - 1.1e-06 28.2 0.0 0.0011 18.7 0.0 3.0 2 0 0 2 2 2 2 WD domain, G-beta repeat XPC-binding PF09280.6 AIO00112.1 - 6.7e-07 28.6 2.9 1.5e-06 27.5 2.0 1.6 1 0 0 1 1 1 1 XPC-binding domain UBA PF00627.26 AIO00112.1 - 1e-05 25.1 0.7 3.8e-05 23.3 0.0 2.4 2 0 0 2 2 2 1 UBA/TS-N domain Lsr2 PF11774.3 AIO00112.1 - 0.052 13.4 0.7 0.1 12.5 0.5 1.5 1 0 0 1 1 1 0 Lsr2 EMP70 PF02990.11 AIO00115.1 - 4.6e-130 434.5 9.5 5.7e-130 434.2 6.6 1.1 1 0 0 1 1 1 1 Endomembrane protein 70 SYS1 PF09801.4 AIO00116.1 - 6.6e-20 71.5 1.7 3.7e-17 62.6 0.2 2.2 2 0 0 2 2 2 2 Integral membrane protein S linking to the trans Golgi network dsrm PF00035.20 AIO00117.1 - 2.1e-08 34.5 0.0 0.96 10.0 0.0 5.7 5 0 0 5 5 5 4 Double-stranded RNA binding motif DUF410 PF04190.8 AIO00117.1 - 0.68 9.4 0.0 1.2 8.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF410) RINGv PF12906.2 AIO00118.1 - 2.4e-11 43.5 9.2 5e-11 42.4 6.4 1.6 1 0 0 1 1 1 1 RING-variant domain zf-RING_2 PF13639.1 AIO00118.1 - 0.0021 17.8 6.9 0.004 16.9 4.8 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING-like PF08746.6 AIO00118.1 - 0.43 10.6 6.3 0.82 9.7 4.4 1.5 1 0 0 1 1 1 0 RING-like domain ABC_tran PF00005.22 AIO00119.1 - 4e-27 95.1 0.1 1.2e-26 93.5 0.0 1.8 2 0 0 2 2 2 1 ABC transporter AAA_21 PF13304.1 AIO00119.1 - 8.3e-10 39.0 0.4 4.4e-07 30.1 0.0 2.2 2 0 0 2 2 2 2 AAA domain SMC_N PF02463.14 AIO00119.1 - 0.00028 20.1 0.0 0.0038 16.4 0.0 2.1 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_10 PF12846.2 AIO00119.1 - 0.0079 15.6 0.2 1.3 8.4 0.1 2.2 1 1 1 2 2 2 1 AAA-like domain DUF770 PF05591.7 AIO00119.1 - 0.012 15.2 0.1 0.021 14.3 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF770) AAA_19 PF13245.1 AIO00119.1 - 0.014 15.1 0.5 0.46 10.2 0.1 3.2 3 0 0 3 3 3 0 Part of AAA domain T2SE PF00437.15 AIO00119.1 - 0.018 13.9 0.0 0.03 13.2 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein SbcCD_C PF13558.1 AIO00119.1 - 0.027 14.3 3.8 0.052 13.4 0.2 3.0 3 1 0 3 3 2 0 Putative exonuclease SbcCD, C subunit AAA_29 PF13555.1 AIO00119.1 - 0.045 13.2 0.0 0.24 10.9 0.0 2.1 2 0 0 2 2 2 0 P-loop containing region of AAA domain DUF258 PF03193.11 AIO00119.1 - 0.047 12.8 0.0 0.083 12.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_25 PF13481.1 AIO00119.1 - 0.048 13.0 0.0 1.6 8.0 0.0 2.5 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.12 AIO00119.1 - 0.085 12.2 0.1 2.4 7.5 0.0 2.3 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_17 PF13207.1 AIO00119.1 - 0.097 13.4 0.1 0.27 12.0 0.1 1.8 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.1 AIO00119.1 - 0.11 12.5 0.8 2.2 8.4 0.1 2.5 2 0 0 2 2 2 0 AAA domain NACHT PF05729.7 AIO00119.1 - 0.15 11.7 1.1 0.46 10.1 0.1 2.1 2 0 0 2 2 2 0 NACHT domain Thioredoxin PF00085.15 AIO00120.1 - 2e-08 33.8 0.0 2.7e-05 23.7 0.0 2.4 2 0 0 2 2 2 2 Thioredoxin Redoxin PF08534.5 AIO00120.1 - 0.0046 16.4 0.4 0.019 14.4 0.0 2.2 3 0 0 3 3 3 1 Redoxin AhpC-TSA PF00578.16 AIO00120.1 - 0.025 14.2 0.0 0.05 13.2 0.0 1.4 1 0 0 1 1 1 0 AhpC/TSA family IncA PF04156.9 AIO00121.1 - 0.0007 19.2 1.4 0.00088 18.9 0.6 1.4 1 1 0 1 1 1 1 IncA protein priB_priC PF07445.7 AIO00121.1 - 0.013 14.9 1.1 0.021 14.3 0.7 1.4 1 0 0 1 1 1 0 Primosomal replication protein priB and priC FUSC PF04632.7 AIO00121.1 - 0.055 11.9 1.5 0.073 11.5 1.1 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family FlaC_arch PF05377.6 AIO00121.1 - 0.057 13.3 0.4 0.91 9.4 0.0 2.6 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) Tropomyosin_1 PF12718.2 AIO00121.1 - 0.42 10.4 3.8 0.15 11.9 0.7 1.7 2 0 0 2 2 2 0 Tropomyosin like 4HBT PF03061.17 AIO00122.1 - 6e-15 55.1 1.9 9.8e-10 38.4 0.4 2.3 2 0 0 2 2 2 2 Thioesterase superfamily 4HBT_2 PF13279.1 AIO00122.1 - 0.0087 16.5 1.0 0.57 10.6 0.6 3.0 1 1 0 1 1 1 1 Thioesterase-like superfamily MaoC_dehydratas PF01575.14 AIO00122.1 - 0.04 13.3 0.1 0.37 10.1 0.1 2.3 2 0 0 2 2 2 0 MaoC like domain DAHP_synth_1 PF00793.15 AIO00122.1 - 0.067 11.8 0.1 0.099 11.3 0.1 1.2 1 0 0 1 1 1 0 DAHP synthetase I family MORN PF02493.15 AIO00123.1 - 2.8e-52 171.4 93.8 2.7e-06 26.7 1.1 21.3 21 0 0 21 21 21 19 MORN repeat TFIIIC_sub6 PF10419.4 AIO00123.1 - 0.0081 15.6 1.7 1.4 8.4 0.0 4.2 4 0 0 4 4 4 1 TFIIIC subunit MutS_V PF00488.16 AIO00124.1 - 1.4e-24 86.8 0.0 2.5e-17 63.1 0.0 2.4 2 0 0 2 2 2 2 MutS domain V MutS_III PF05192.13 AIO00124.1 - 7e-23 81.4 0.0 1.2e-22 80.6 0.0 1.4 1 0 0 1 1 1 1 MutS domain III AAA_29 PF13555.1 AIO00124.1 - 0.0052 16.2 0.0 0.012 15.1 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.1 AIO00124.1 - 0.013 15.4 0.1 0.043 13.7 0.1 1.8 1 0 0 1 1 1 0 AAA ATPase domain AAA_30 PF13604.1 AIO00124.1 - 0.054 13.0 0.0 0.14 11.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain SMC_N PF02463.14 AIO00124.1 - 0.29 10.3 0.0 0.5 9.5 0.0 1.3 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain Flagellar_rod PF05149.7 AIO00125.1 - 3.4e-106 354.6 29.6 3.4e-106 354.6 20.5 2.8 2 1 1 3 3 3 2 Paraflagellar rod protein Diphthamide_syn PF01866.12 AIO00126.1 - 1e-113 379.6 0.0 1.3e-113 379.3 0.0 1.1 1 0 0 1 1 1 1 Putative diphthamide synthesis protein BRCT PF00533.21 AIO00127.1 - 4.1e-12 46.0 0.0 0.0088 16.1 0.0 5.1 6 0 0 6 6 6 3 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.2 AIO00127.1 - 1.5e-09 37.6 5.6 0.013 15.2 1.1 5.5 5 2 0 5 5 5 3 twin BRCT domain Ribosomal_S8 PF00410.14 AIO00128.1 - 2e-23 82.6 0.0 2.9e-23 82.1 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S8 Folliculin PF11704.3 AIO00130.1 - 7.5e-08 32.1 0.1 3.1e-07 30.1 0.0 2.0 2 0 0 2 2 2 1 Vesicle coat protein involved in Golgi to plasma membrane transport Bac_surface_Ag PF01103.18 AIO00131.1 - 4.6e-19 69.0 0.4 8.3e-19 68.1 0.3 1.4 1 0 0 1 1 1 1 Surface antigen Pyr_redox_2 PF07992.9 AIO00132.1 - 1.8e-27 96.5 0.1 2.8e-27 95.9 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.17 AIO00132.1 - 3.5e-19 68.8 0.3 8.7e-19 67.5 0.0 1.8 2 0 0 2 2 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.22 AIO00132.1 - 4.2e-19 68.7 1.9 1.7e-16 60.3 0.0 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 AIO00132.1 - 7.3e-12 45.7 0.8 4.6e-09 36.6 0.2 3.1 1 1 2 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 AIO00132.1 - 1.1e-08 34.5 0.1 1.8e-08 33.9 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase DAO PF01266.19 AIO00132.1 - 1.6e-06 27.3 3.5 0.00037 19.5 0.0 2.9 3 0 0 3 3 3 2 FAD dependent oxidoreductase GIDA PF01134.17 AIO00132.1 - 1.8e-06 27.0 2.3 0.015 14.1 0.1 3.7 4 0 0 4 4 4 2 Glucose inhibited division protein A K_oxygenase PF13434.1 AIO00132.1 - 1.4e-05 24.2 0.0 4.5e-05 22.5 0.0 1.8 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) FAD_binding_3 PF01494.14 AIO00132.1 - 2e-05 23.8 1.2 0.026 13.5 0.1 3.2 2 1 0 3 3 3 2 FAD binding domain HI0933_like PF03486.9 AIO00132.1 - 0.00011 20.8 5.8 0.0016 17.0 0.4 3.4 3 1 1 4 4 4 1 HI0933-like protein FAD_binding_2 PF00890.19 AIO00132.1 - 0.00012 21.0 0.5 0.00012 21.0 0.4 2.8 4 0 0 4 4 4 1 FAD binding domain Thi4 PF01946.12 AIO00132.1 - 0.00045 19.3 0.2 0.034 13.2 0.0 2.3 2 0 0 2 2 2 1 Thi4 family ThiF PF00899.16 AIO00132.1 - 0.0017 18.1 0.0 0.0055 16.5 0.0 1.8 1 0 0 1 1 1 1 ThiF family 3HCDH_N PF02737.13 AIO00132.1 - 0.0026 17.4 0.0 0.0054 16.3 0.0 1.6 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_8 PF13450.1 AIO00132.1 - 0.0069 16.3 4.6 0.39 10.7 0.6 2.5 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain AlaDh_PNT_C PF01262.16 AIO00132.1 - 0.022 14.3 0.3 1 8.8 0.0 2.3 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.14 AIO00132.1 - 0.035 13.2 0.2 0.088 11.9 0.0 1.8 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_7 PF13241.1 AIO00132.1 - 0.056 13.6 0.0 18 5.6 0.0 2.6 2 1 0 2 2 2 0 Putative NAD(P)-binding XPG_N PF00752.12 AIO00133.1 - 0.025 14.8 0.1 0.098 12.9 0.0 2.0 2 0 0 2 2 2 0 XPG N-terminal domain Filament PF00038.16 AIO00133.1 - 0.074 12.5 26.3 0.92 8.9 3.6 2.6 1 1 1 2 2 2 0 Intermediate filament protein BLOC1_2 PF10046.4 AIO00133.1 - 0.077 13.1 14.5 1.5 9.0 0.5 3.7 1 1 3 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 UCR_hinge PF02320.11 AIO00133.1 - 0.25 11.3 4.0 8 6.4 0.4 2.7 2 0 0 2 2 2 0 Ubiquinol-cytochrome C reductase hinge protein DUF1664 PF07889.7 AIO00133.1 - 0.36 10.6 13.8 0.59 9.9 2.6 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) DUF1993 PF09351.5 AIO00133.1 - 0.39 10.6 11.0 0.16 11.8 4.7 2.2 2 1 0 2 2 2 0 Domain of unknown function (DUF1993) DUF2730 PF10805.3 AIO00133.1 - 0.63 9.7 9.5 4.3 7.1 0.1 3.8 2 2 1 3 3 3 0 Protein of unknown function (DUF2730) Cep57_CLD PF14073.1 AIO00133.1 - 1.5 8.6 30.3 0.025 14.4 14.5 2.1 1 1 1 2 2 2 0 Centrosome localisation domain of Cep57 NPV_P10 PF05531.7 AIO00133.1 - 1.9 8.8 17.4 12 6.2 0.0 4.7 3 1 2 5 5 5 0 Nucleopolyhedrovirus P10 protein DUF2098 PF09871.4 AIO00133.1 - 2.7 7.9 5.1 2.5 8.1 0.1 2.5 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2098) Med10 PF09748.4 AIO00133.1 - 3.4 7.5 9.4 1.2 8.9 1.0 3.5 1 1 1 2 2 2 0 Transcription factor subunit Med10 of Mediator complex DUF342 PF03961.8 AIO00133.1 - 4 5.7 15.1 2 6.7 0.6 2.2 1 1 0 2 2 2 0 Protein of unknown function (DUF342) DUF2972 PF11186.3 AIO00133.1 - 4.6 7.0 7.1 22 4.8 4.6 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2972) Bacillus_HBL PF05791.6 AIO00133.1 - 8.2 5.7 16.2 0.43 9.9 4.8 2.7 1 1 2 3 3 3 0 Bacillus haemolytic enterotoxin (HBL) DIT1_PvcA PF05141.7 AIO00133.1 - 9 5.5 11.4 0.74 9.0 2.3 2.4 1 1 2 3 3 3 0 Pyoverdine/dityrosine biosynthesis protein PIH1 PF08190.7 AIO00134.1 - 7.6e-11 42.0 0.0 9.6e-11 41.6 0.0 1.2 1 0 0 1 1 1 1 pre-RNA processing PIH1/Nop17 Herpes_BLLF1 PF05109.8 AIO00135.1 - 1.8 6.4 18.8 2.4 6.0 13.0 1.1 1 0 0 1 1 1 0 Herpes virus major outer envelope glycoprotein (BLLF1) zf-met2 PF12907.2 AIO00136.1 - 0.00044 20.1 0.9 0.001 18.9 0.6 1.6 1 1 0 1 1 1 1 Zinc-binding DnaJ PF00226.26 AIO00138.1 - 1.5e-08 34.2 0.0 4e-08 32.8 0.0 1.7 1 0 0 1 1 1 1 DnaJ domain Condensation PF00668.15 AIO00138.1 - 1.4 7.6 5.9 0.15 10.8 0.2 1.9 2 0 0 2 2 2 0 Condensation domain Zn_ribbon_recom PF13408.1 AIO00139.1 - 0.049 13.8 0.3 0.1 12.8 0.2 1.4 1 0 0 1 1 1 0 Recombinase zinc beta ribbon domain SH3BP5 PF05276.9 AIO00139.1 - 0.051 12.8 0.2 0.5 9.6 0.1 2.0 2 0 0 2 2 2 0 SH3 domain-binding protein 5 (SH3BP5) zinc_ribbon_2 PF13240.1 AIO00139.1 - 0.088 12.3 0.2 0.23 10.9 0.2 1.6 1 0 0 1 1 1 0 zinc-ribbon domain EF-hand_7 PF13499.1 AIO00142.1 - 2.7e-08 33.8 0.1 0.071 13.2 0.0 4.0 2 2 1 3 3 3 3 EF-hand domain pair EF-hand_6 PF13405.1 AIO00142.1 - 7.1e-05 22.3 0.0 3.4 7.8 0.0 4.0 4 0 0 4 4 4 2 EF-hand domain EF-hand_1 PF00036.27 AIO00142.1 - 0.019 14.2 2.1 0.45 9.9 0.1 3.8 5 0 0 5 5 5 0 EF hand FliJ PF02050.11 AIO00143.1 - 0.048 13.7 0.4 0.048 13.7 0.3 1.7 2 0 0 2 2 2 0 Flagellar FliJ protein Phospholip_B PF04916.8 AIO00143.1 - 0.12 10.4 0.1 0.12 10.4 0.1 1.1 1 0 0 1 1 1 0 Phospholipase B EST1 PF10374.4 AIO00143.1 - 2.4 8.1 4.9 1.3 8.9 1.2 1.8 1 1 1 2 2 2 0 Telomerase activating protein Est1 PPTA PF01239.17 AIO00144.1 - 8.7e-21 72.3 20.0 2.6e-09 36.0 0.2 5.4 5 0 0 5 5 5 5 Protein prenyltransferase alpha subunit repeat Fumerase PF05681.9 AIO00145.1 - 1.3e-85 286.7 0.0 1.7e-85 286.4 0.0 1.1 1 0 0 1 1 1 1 Fumarate hydratase (Fumerase) Fumerase_C PF05683.7 AIO00145.1 - 8.7e-82 273.2 0.0 1.4e-81 272.5 0.0 1.3 1 0 0 1 1 1 1 Fumarase C-terminus Fib_alpha PF08702.5 AIO00146.1 - 4.6 7.3 34.3 0.28 11.3 5.7 6.3 5 1 2 7 7 7 0 Fibrinogen alpha/beta chain family Ca_hom_mod PF14798.1 AIO00147.1 - 0.15 10.9 0.1 0.25 10.2 0.1 1.2 1 0 0 1 1 1 0 Calcium homeostasis modulator Nol1_Nop2_Fmu PF01189.12 AIO00149.1 - 4.4e-15 55.8 0.0 3.4e-05 23.3 0.0 3.5 3 0 0 3 3 3 3 NOL1/NOP2/sun family Methyltransf_26 PF13659.1 AIO00149.1 - 0.00031 20.7 0.1 0.0034 17.4 0.0 2.6 1 1 0 1 1 1 1 Methyltransferase domain PPR_2 PF13041.1 AIO00150.1 - 2.4e-05 24.2 0.0 0.1 12.5 0.0 3.5 4 1 1 5 5 5 2 PPR repeat family PPR_3 PF13812.1 AIO00150.1 - 0.0012 18.9 1.5 86 3.8 0.0 5.8 6 1 0 6 6 6 0 Pentatricopeptide repeat domain PPR PF01535.15 AIO00150.1 - 0.0049 16.7 0.2 12 6.1 0.0 4.1 4 0 0 4 4 4 1 PPR repeat TPR_14 PF13428.1 AIO00150.1 - 0.31 11.7 4.3 6.6 7.6 0.0 5.0 3 1 3 6 6 6 0 Tetratricopeptide repeat Pkinase PF00069.20 AIO00151.1 - 2.5e-74 249.7 0.0 3.4e-74 249.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AIO00151.1 - 3.5e-40 137.7 0.0 5e-40 137.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 AIO00151.1 - 2.1e-06 26.8 0.0 8.6e-06 24.9 0.0 1.8 2 0 0 2 2 2 1 Kinase-like RIO1 PF01163.17 AIO00151.1 - 7.7e-06 25.3 0.2 0.00021 20.6 0.0 2.1 1 1 1 2 2 2 1 RIO1 family Kdo PF06293.9 AIO00151.1 - 0.00042 19.4 0.0 0.00078 18.5 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 AIO00151.1 - 0.0013 18.4 0.3 0.072 12.8 0.1 2.5 3 0 0 3 3 3 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 AIO00151.1 - 0.22 11.0 0.1 0.66 9.5 0.0 1.8 1 1 0 1 1 1 0 Choline/ethanolamine kinase Gpi1 PF05024.10 AIO00152.1 - 2.5e-28 99.0 10.2 8e-21 74.5 2.9 2.6 3 0 0 3 3 3 2 N-acetylglucosaminyl transferase component (Gpi1) Cse1 PF08506.5 AIO00155.1 - 0.042 12.3 0.0 0.1 11.1 0.0 1.6 1 0 0 1 1 1 0 Cse1 adh_short PF00106.20 AIO00157.1 - 1.4e-07 31.5 0.1 3.1e-07 30.4 0.1 1.6 1 0 0 1 1 1 1 short chain dehydrogenase ApbA PF02558.11 AIO00157.1 - 0.08 12.3 0.3 1.3 8.4 0.1 2.3 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA DUF1426 PF07234.6 AIO00157.1 - 1.9 8.2 5.0 6.4 6.5 3.4 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF1426) DUF1289 PF06945.8 AIO00158.1 - 0.58 9.6 3.2 1.1 8.7 2.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1289) AAA_12 PF13087.1 AIO00159.1 - 2.2e-34 118.5 0.0 3.5e-34 117.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 AIO00159.1 - 5.9e-19 68.5 0.0 1e-17 64.4 0.0 2.7 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.1 AIO00159.1 - 2e-08 34.0 0.1 0.002 17.7 0.0 3.0 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.1 AIO00159.1 - 9.3e-05 22.1 1.6 0.00072 19.2 0.0 3.2 3 0 0 3 3 3 1 Part of AAA domain PhoH PF02562.11 AIO00159.1 - 0.0012 18.0 0.1 0.11 11.7 0.0 3.1 3 0 0 3 3 3 1 PhoH-like protein AAA_22 PF13401.1 AIO00159.1 - 0.0067 16.5 0.2 0.5 10.5 0.0 3.4 4 0 0 4 4 4 1 AAA domain Viral_helicase1 PF01443.13 AIO00159.1 - 0.014 14.9 1.2 1.6 8.1 0.0 3.3 3 0 0 3 3 3 0 Viral (Superfamily 1) RNA helicase DUF2075 PF09848.4 AIO00159.1 - 0.017 14.1 0.2 0.033 13.1 0.0 1.5 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_17 PF13207.1 AIO00159.1 - 0.018 15.8 0.0 0.054 14.3 0.0 1.9 1 1 0 1 1 1 0 AAA domain CSD PF00313.17 AIO00159.1 - 0.074 12.8 0.1 0.15 11.8 0.0 1.5 1 0 0 1 1 1 0 'Cold-shock' DNA-binding domain SPX PF03105.14 AIO00159.1 - 0.7 9.6 0.8 1.2 8.8 0.6 1.3 1 0 0 1 1 1 0 SPX domain DUF4139 PF13598.1 AIO00160.1 - 9.7e-69 232.0 0.1 1.3e-68 231.6 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4139) UDP-g_GGTase PF06427.6 AIO00161.1 - 3.4e-55 186.6 0.1 6.2e-55 185.7 0.0 1.4 1 0 0 1 1 1 1 UDP-glucose:Glycoprotein Glucosyltransferase Glyco_transf_8 PF01501.15 AIO00161.1 - 9.5e-05 21.8 0.1 0.00019 20.8 0.1 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 8 VIT1 PF01988.14 AIO00162.1 - 1.5e-16 60.5 2.5 2.2e-16 60.0 1.7 1.4 1 1 0 1 1 1 1 VIT family LRR_4 PF12799.2 AIO00163.1 - 6.1e-11 41.6 19.2 0.00016 21.2 0.1 6.0 6 2 2 8 8 8 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 AIO00163.1 - 5.8e-07 28.6 24.3 1.5 9.1 0.2 9.1 7 3 2 9 9 9 4 Leucine Rich Repeat LRR_8 PF13855.1 AIO00163.1 - 0.00039 20.1 15.4 0.034 13.8 0.2 5.2 2 2 3 5 5 5 3 Leucine rich repeat LRR_7 PF13504.1 AIO00163.1 - 0.011 15.8 20.3 3 8.4 0.1 8.0 9 0 0 9 9 9 0 Leucine rich repeat FNIP PF05725.7 AIO00163.1 - 0.011 15.6 4.3 1.8 8.5 0.1 4.2 3 1 1 4 4 4 0 FNIP Repeat LRR_6 PF13516.1 AIO00163.1 - 0.082 13.0 17.8 7.1 7.0 0.0 8.0 6 2 2 8 8 8 0 Leucine Rich repeat ERG2_Sigma1R PF04622.7 AIO00164.1 - 4.1e-71 238.6 0.5 4.9e-71 238.4 0.3 1.0 1 0 0 1 1 1 1 ERG2 and Sigma1 receptor like protein Pkinase PF00069.20 AIO00165.1 - 4.1e-43 147.3 0.0 5.8e-43 146.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AIO00165.1 - 1.3e-15 57.1 0.0 3.2e-15 55.8 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase GDI PF00996.13 AIO00166.1 - 3e-172 572.8 0.0 3.4e-172 572.6 0.0 1.0 1 0 0 1 1 1 1 GDP dissociation inhibitor DTW PF03942.10 AIO00167.1 - 1.1e-15 57.3 0.8 3.4e-15 55.8 0.1 2.2 2 1 0 2 2 2 1 DTW domain Y2_Tnp PF04986.8 AIO00167.1 - 0.024 14.4 0.2 0.086 12.5 0.0 1.9 2 0 0 2 2 2 0 Putative transposase APP_E2 PF12925.2 AIO00167.1 - 0.075 12.6 1.7 0.13 11.8 0.0 2.1 2 0 0 2 2 2 0 E2 domain of amyloid precursor protein DUF4379 PF14311.1 AIO00168.1 - 8.1e-40 134.4 15.5 8e-14 51.1 0.3 3.4 3 0 0 3 3 3 3 Domain of unknown function (DUF4379) SprT-like PF10263.4 AIO00168.1 - 0.21 11.2 5.1 7 6.2 0.2 3.0 3 0 0 3 3 3 0 SprT-like family Lar_restr_allev PF14354.1 AIO00168.1 - 0.52 10.6 10.6 0.69 10.2 0.2 4.4 4 1 0 4 4 4 0 Restriction alleviation protein Lar DnaJ_CXXCXGXG PF00684.14 AIO00168.1 - 0.59 10.2 0.1 0.59 10.2 0.0 3.4 3 2 0 3 3 3 0 DnaJ central domain DUF2072 PF09845.4 AIO00168.1 - 6.4 6.7 8.6 0.21 11.5 0.5 2.5 2 1 1 3 3 3 0 Zn-ribbon containing protein (DUF2072) Dynamin_M PF01031.15 AIO00170.1 - 3.2e-91 305.1 0.4 6.6e-91 304.1 0.3 1.5 1 0 0 1 1 1 1 Dynamin central region Dynamin_N PF00350.18 AIO00170.1 - 5.5e-50 169.4 0.1 2.3e-49 167.4 0.0 2.1 2 0 0 2 2 2 1 Dynamin family GED PF02212.13 AIO00170.1 - 8.9e-24 83.2 0.4 3.2e-23 81.4 0.3 2.0 1 0 0 1 1 1 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.18 AIO00170.1 - 0.00013 21.9 0.1 0.00097 19.0 0.1 2.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase p450 PF00067.17 AIO00170.1 - 0.015 13.8 0.0 0.031 12.8 0.0 1.4 1 0 0 1 1 1 0 Cytochrome P450 FeoB_N PF02421.13 AIO00170.1 - 0.019 14.2 0.4 3.7 6.8 0.0 3.0 3 0 0 3 3 3 0 Ferrous iron transport protein B Miro PF08477.8 AIO00170.1 - 0.026 15.0 0.0 0.069 13.6 0.0 1.8 1 0 0 1 1 1 0 Miro-like protein LRR_9 PF14580.1 AIO00171.1 - 1.8e-13 50.4 0.4 2.8e-13 49.7 0.3 1.3 1 0 0 1 1 1 1 Leucine-rich repeat LRR_4 PF12799.2 AIO00171.1 - 1.3e-09 37.4 2.4 7.3e-05 22.2 0.1 3.6 1 1 3 4 4 4 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 AIO00171.1 - 2e-07 30.6 4.1 3.7e-07 29.8 0.4 2.8 3 0 0 3 3 3 1 Leucine rich repeat LRR_1 PF00560.28 AIO00171.1 - 0.0022 17.7 1.7 17 5.9 0.0 4.4 4 0 0 4 4 4 1 Leucine Rich Repeat LRR_6 PF13516.1 AIO00171.1 - 0.0055 16.6 3.0 2 8.7 0.0 3.9 4 1 1 5 5 5 1 Leucine Rich repeat ApbA PF02558.11 AIO00173.1 - 0.091 12.2 0.0 0.22 10.9 0.0 1.8 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Peptidase_M1 PF01433.15 AIO00174.1 - 6.5e-95 318.4 0.0 9.6e-95 317.9 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M1 ERAP1_C PF11838.3 AIO00174.1 - 3.8e-17 62.5 0.0 5.8e-17 61.9 0.0 1.3 1 0 0 1 1 1 1 ERAP1-like C-terminal domain Peptidase_MA_2 PF13485.1 AIO00174.1 - 1.6e-12 47.6 0.0 3.9e-12 46.3 0.0 1.7 1 1 0 1 1 1 1 Peptidase MA superfamily DUF2968 PF11180.3 AIO00175.1 - 0.0042 16.4 11.4 0.0042 16.4 7.9 3.6 3 0 0 3 3 3 1 Protein of unknown function (DUF2968) TPR_MLP1_2 PF07926.7 AIO00175.1 - 0.0067 16.1 34.5 0.11 12.1 2.8 3.5 3 0 0 3 3 3 2 TPR/MLP1/MLP2-like protein Tropomyosin PF00261.15 AIO00175.1 - 0.0077 15.3 5.5 0.0077 15.3 3.8 3.5 3 0 0 3 3 3 1 Tropomyosin ATG16 PF08614.6 AIO00175.1 - 0.016 15.0 31.1 0.17 11.7 3.5 3.9 2 1 1 3 3 3 0 Autophagy protein 16 (ATG16) Filament PF00038.16 AIO00175.1 - 0.032 13.7 30.1 0.05 13.0 3.9 3.4 3 0 0 3 3 3 0 Intermediate filament protein DUF745 PF05335.8 AIO00175.1 - 0.033 13.7 35.4 0.023 14.2 1.8 4.4 4 0 0 4 4 4 0 Protein of unknown function (DUF745) Atg14 PF10186.4 AIO00175.1 - 0.048 12.5 27.4 0.023 13.6 5.0 3.5 4 0 0 4 4 4 0 UV radiation resistance protein and autophagy-related subunit 14 MIT PF04212.13 AIO00175.1 - 0.23 11.3 9.1 0.23 11.3 0.6 3.4 3 0 0 3 3 3 0 MIT (microtubule interacting and transport) domain IncA PF04156.9 AIO00175.1 - 1.1 8.8 33.8 0.029 13.9 5.6 3.7 4 0 0 4 4 4 0 IncA protein Fib_alpha PF08702.5 AIO00175.1 - 1.1 9.3 16.6 0.43 10.7 1.5 3.6 3 0 0 3 3 3 0 Fibrinogen alpha/beta chain family TBPIP PF07106.8 AIO00175.1 - 1.3 8.5 22.8 0.69 9.4 3.7 3.3 3 0 0 3 3 3 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Mod_r PF07200.8 AIO00175.1 - 1.6 8.6 23.9 0.74 9.7 2.3 3.3 3 0 0 3 3 3 0 Modifier of rudimentary (Mod(r)) protein ADIP PF11559.3 AIO00175.1 - 1.9 8.4 40.8 0.36 10.7 4.3 3.7 4 0 0 4 4 3 0 Afadin- and alpha -actinin-Binding Syntaxin-6_N PF09177.6 AIO00175.1 - 2.9 8.3 20.5 3.1 8.2 1.2 4.0 3 0 0 3 3 3 0 Syntaxin 6, N-terminal SPX PF03105.14 AIO00175.1 - 4.2 7.0 9.5 15 5.2 6.6 1.9 1 0 0 1 1 1 0 SPX domain CENP-F_leu_zip PF10473.4 AIO00175.1 - 4.9 6.9 37.0 0.46 10.3 0.9 5.0 4 1 1 5 5 5 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 FlxA PF14282.1 AIO00175.1 - 5.1 7.0 29.4 5.5 7.0 7.2 3.9 4 0 0 4 4 3 0 FlxA-like protein SlyX PF04102.7 AIO00175.1 - 5.7 7.3 0.0 5.7 7.3 0.0 7.2 5 3 3 8 8 8 0 SlyX Sld5 PF05916.6 AIO00176.1 - 0.0005 20.3 0.0 0.0009 19.5 0.0 1.4 1 0 0 1 1 1 1 GINS complex protein MraY_sig1 PF10555.4 AIO00176.1 - 0.041 13.1 1.4 0.1 11.9 0.9 1.7 1 0 0 1 1 1 0 Phospho-N-acetylmuramoyl-pentapeptide-transferase signature 1 Acyltransferase PF01553.16 AIO00177.1 - 3.6e-10 39.4 0.0 6.4e-10 38.5 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase UCH PF00443.24 AIO00179.1 - 1.1e-49 168.9 0.0 7.8e-49 166.1 0.0 2.0 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.14 AIO00179.1 - 1e-15 57.5 5.7 1e-15 57.5 4.0 3.8 3 0 0 3 3 3 1 Zn-finger in ubiquitin-hydrolases and other protein UCH_1 PF13423.1 AIO00179.1 - 6.7e-15 55.3 0.0 2.7e-14 53.3 0.0 2.0 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UBA PF00627.26 AIO00179.1 - 5.5e-06 26.0 0.0 1.3e-05 24.9 0.0 1.7 1 0 0 1 1 1 1 UBA/TS-N domain CUE PF02845.11 AIO00179.1 - 0.046 13.2 0.0 0.092 12.2 0.0 1.5 1 0 0 1 1 1 0 CUE domain UBA_4 PF14555.1 AIO00179.1 - 0.078 12.5 0.0 0.16 11.4 0.0 1.5 1 0 0 1 1 1 0 UBA-like domain ECH PF00378.15 AIO00180.1 - 3.7e-68 229.3 1.5 4.1e-68 229.1 1.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family ECH_C PF13766.1 AIO00180.1 - 0.00062 19.9 0.2 0.0016 18.5 0.1 1.7 1 0 0 1 1 1 1 2-enoyl-CoA Hydratase C-terminal region Peptidase_S49 PF01343.13 AIO00180.1 - 0.0029 17.4 0.1 0.14 11.9 0.0 2.3 2 0 0 2 2 2 1 Peptidase family S49 Pkinase PF00069.20 AIO00181.1 - 1.4e-53 181.6 0.0 2e-53 181.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AIO00181.1 - 3.2e-35 121.4 0.0 5.4e-35 120.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 AIO00181.1 - 0.00012 21.8 0.0 0.074 12.7 0.0 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.6 AIO00181.1 - 0.0065 15.3 0.1 0.0097 14.7 0.0 1.2 1 0 0 1 1 1 1 Poxvirus serine/threonine protein kinase Seadorna_VP7 PF07387.6 AIO00181.1 - 0.014 14.2 0.0 0.039 12.7 0.0 1.7 2 0 0 2 2 2 0 Seadornavirus VP7 Macoilin PF09726.4 AIO00182.1 - 0.0033 15.8 5.2 0.0073 14.6 1.0 2.0 2 0 0 2 2 2 2 Transmembrane protein DUF1664 PF07889.7 AIO00182.1 - 0.44 10.3 3.9 1.4 8.7 0.1 3.0 3 1 1 4 4 4 0 Protein of unknown function (DUF1664) NAP PF00956.13 AIO00183.1 - 6.6e-20 71.2 1.2 3.4e-18 65.6 0.0 2.0 1 1 1 2 2 2 2 Nucleosome assembly protein (NAP) COQ7 PF03232.8 AIO00184.1 - 7e-61 204.6 0.1 8.1e-61 204.4 0.1 1.0 1 0 0 1 1 1 1 Ubiquinone biosynthesis protein COQ7 Peptidase_M18 PF02127.10 AIO00185.1 - 6.1e-154 512.6 0.0 6.9e-154 512.4 0.0 1.0 1 0 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) Peptidase_M42 PF05343.9 AIO00185.1 - 4.5e-08 32.1 0.0 1.1e-05 24.4 0.0 2.2 1 1 0 1 1 1 1 M42 glutamyl aminopeptidase Ribosomal_L39 PF00832.15 AIO00186.1 - 2.3e-19 68.5 14.3 2.6e-19 68.3 9.9 1.0 1 0 0 1 1 1 1 Ribosomal L39 protein Methyltransf_FA PF12248.3 AIO00186.1 - 0.081 12.9 0.0 0.089 12.8 0.0 1.1 1 0 0 1 1 1 0 Farnesoic acid 0-methyl transferase Ran-binding PF05508.6 AIO00187.1 - 0.1 11.4 0.7 0.15 10.9 0.5 1.2 1 0 0 1 1 1 0 RanGTP-binding protein TBPIP PF07106.8 AIO00187.1 - 0.12 11.8 1.3 0.17 11.4 0.9 1.2 1 0 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) CENP-Q PF13094.1 AIO00187.1 - 0.74 9.8 5.7 1 9.3 4.0 1.2 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit Kinesin PF00225.18 AIO00188.1 - 2.5e-92 309.1 0.1 3.1e-92 308.8 0.0 1.1 1 0 0 1 1 1 1 Kinesin motor domain C2 PF00168.25 AIO00188.1 - 0.00096 18.9 0.0 0.0037 17.0 0.0 2.0 2 0 0 2 2 2 1 C2 domain NIF PF03031.13 AIO00189.1 - 6.7e-32 110.3 0.0 1e-31 109.7 0.0 1.3 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase DUF705 PF05152.7 AIO00189.1 - 0.002 17.1 0.0 0.0031 16.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF705) zf-CCCH_2 PF14608.1 AIO00189.1 - 0.4 10.7 1.6 0.78 9.8 1.1 1.5 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type Acyltransferase PF01553.16 AIO00190.1 - 9.5e-11 41.2 0.0 1.6e-10 40.5 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase JmjN PF02375.12 AIO00190.1 - 0.043 13.3 0.0 0.09 12.3 0.0 1.5 1 0 0 1 1 1 0 jmjN domain Herpes_US9 PF06072.6 AIO00190.1 - 0.56 10.0 4.6 0.36 10.6 0.5 2.5 2 0 0 2 2 2 0 Alphaherpesvirus tegument protein US9 DUF1731 PF08338.6 AIO00192.1 - 0.026 14.0 0.0 0.061 12.8 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1731) PDEase_I PF00233.14 AIO00193.1 - 5.4e-61 206.3 0.9 8.1e-61 205.7 0.6 1.3 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase HSP20 PF00011.16 AIO00194.1 - 3.8e-17 61.9 0.0 4.6e-17 61.7 0.0 1.1 1 0 0 1 1 1 1 Hsp20/alpha crystallin family PapC_N PF13954.1 AIO00194.1 - 0.063 12.8 0.0 0.091 12.3 0.0 1.3 1 0 0 1 1 1 0 PapC N-terminal domain Ribosomal_L13e PF01294.13 AIO00195.1 - 1.6e-53 180.8 5.8 1.6e-53 180.7 3.5 1.4 1 1 0 1 1 1 1 Ribosomal protein L13e PTPS PF01242.14 AIO00195.1 - 0.11 12.2 0.0 0.16 11.6 0.0 1.2 1 0 0 1 1 1 0 6-pyruvoyl tetrahydropterin synthase DUF4169 PF13770.1 AIO00195.1 - 0.22 11.5 0.2 0.22 11.5 0.1 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4169) Pkinase PF00069.20 AIO00197.1 - 1.3e-44 152.2 0.0 2e-44 151.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AIO00197.1 - 2.3e-35 121.9 0.0 2.9e-35 121.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pox_ser-thr_kin PF05445.6 AIO00197.1 - 0.0053 15.6 0.2 0.0094 14.7 0.1 1.3 1 0 0 1 1 1 1 Poxvirus serine/threonine protein kinase APH PF01636.18 AIO00197.1 - 0.042 13.5 0.1 0.081 12.6 0.1 1.5 1 1 0 1 1 1 0 Phosphotransferase enzyme family Choline_kinase PF01633.15 AIO00197.1 - 0.057 12.9 0.0 0.097 12.2 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase Kdo PF06293.9 AIO00197.1 - 0.063 12.3 0.0 0.11 11.4 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family AAA PF00004.24 AIO00198.1 - 2.8e-40 137.5 0.0 6.8e-40 136.3 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.5 AIO00198.1 - 5.3e-27 93.4 0.2 1.3e-26 92.2 0.2 1.7 1 0 0 1 1 1 1 Vps4 C terminal oligomerisation domain MIT PF04212.13 AIO00198.1 - 1e-19 70.1 3.4 1.6e-19 69.5 1.4 2.1 2 0 0 2 2 1 1 MIT (microtubule interacting and transport) domain AAA_17 PF13207.1 AIO00198.1 - 5.4e-07 30.4 0.2 3.5e-06 27.8 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_2 PF07724.9 AIO00198.1 - 2.9e-06 27.3 0.0 8.1e-06 25.8 0.0 1.8 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.1 AIO00198.1 - 9.1e-06 25.8 0.8 0.0003 20.9 0.1 3.0 3 1 0 3 3 2 1 AAA domain AAA_16 PF13191.1 AIO00198.1 - 2.4e-05 24.3 0.1 0.00047 20.2 0.0 2.2 1 1 1 2 2 2 1 AAA ATPase domain AAA_25 PF13481.1 AIO00198.1 - 4.3e-05 23.0 0.6 0.19 11.0 0.1 2.5 1 1 1 2 2 2 2 AAA domain AAA_5 PF07728.9 AIO00198.1 - 6.4e-05 22.7 0.0 0.00034 20.3 0.0 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.12 AIO00198.1 - 0.00017 21.0 0.0 0.00032 20.1 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_33 PF13671.1 AIO00198.1 - 0.00019 21.3 0.0 0.00054 19.8 0.0 1.9 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.7 AIO00198.1 - 0.00053 19.1 0.0 0.0011 18.0 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_14 PF13173.1 AIO00198.1 - 0.00058 19.7 0.0 0.0019 18.1 0.0 1.8 2 0 0 2 2 1 1 AAA domain AAA_24 PF13479.1 AIO00198.1 - 0.0012 18.4 0.1 0.021 14.4 0.0 2.2 2 0 0 2 2 2 1 AAA domain TIP49 PF06068.8 AIO00198.1 - 0.0013 17.5 0.0 0.002 16.9 0.0 1.3 1 0 0 1 1 1 1 TIP49 C-terminus DUF815 PF05673.8 AIO00198.1 - 0.0013 17.6 0.0 0.0022 16.9 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) USP8_dimer PF08969.6 AIO00198.1 - 0.0051 16.7 3.3 0.013 15.4 2.3 1.6 1 0 0 1 1 1 1 USP8 dimerisation domain PPV_E1_C PF00519.12 AIO00198.1 - 0.0062 15.2 0.0 0.0091 14.6 0.0 1.2 1 0 0 1 1 1 1 Papillomavirus helicase RNA_helicase PF00910.17 AIO00198.1 - 0.0077 16.3 0.0 0.019 15.0 0.0 1.7 1 0 0 1 1 1 1 RNA helicase AAA_18 PF13238.1 AIO00198.1 - 0.0082 16.4 0.1 0.031 14.5 0.0 2.1 2 0 0 2 2 1 1 AAA domain ResIII PF04851.10 AIO00198.1 - 0.012 15.4 0.1 0.27 11.0 0.0 2.2 1 1 1 2 2 2 0 Type III restriction enzyme, res subunit Arch_ATPase PF01637.13 AIO00198.1 - 0.013 15.2 2.9 0.77 9.4 0.0 2.9 2 2 1 3 3 3 0 Archaeal ATPase AAA_19 PF13245.1 AIO00198.1 - 0.016 14.9 0.0 0.062 13.0 0.0 2.0 2 0 0 2 2 1 0 Part of AAA domain Zeta_toxin PF06414.7 AIO00198.1 - 0.023 13.8 0.0 0.05 12.6 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin Viral_helicase1 PF01443.13 AIO00198.1 - 0.028 13.9 0.0 0.049 13.1 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase Mg_chelatase PF01078.16 AIO00198.1 - 0.037 13.1 0.0 0.076 12.1 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI CPT PF07931.7 AIO00198.1 - 0.044 13.4 0.0 0.13 11.8 0.0 1.9 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein Parvo_NS1 PF01057.12 AIO00198.1 - 0.058 12.2 0.0 0.12 11.2 0.0 1.4 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 NACHT PF05729.7 AIO00198.1 - 0.073 12.7 0.0 0.67 9.5 0.0 2.1 1 1 2 3 3 3 0 NACHT domain PhoH PF02562.11 AIO00198.1 - 0.074 12.2 0.0 0.18 10.9 0.0 1.6 1 0 0 1 1 1 0 PhoH-like protein AAA_21 PF13304.1 AIO00198.1 - 0.089 12.7 1.5 3.4 7.5 0.0 2.7 2 1 0 3 3 2 0 AAA domain AAA_28 PF13521.1 AIO00198.1 - 0.11 12.5 0.0 0.33 10.8 0.0 1.9 1 1 0 1 1 1 0 AAA domain PFK PF00365.15 AIO00199.1 - 3.2e-37 128.0 1.5 4.7e-37 127.4 1.0 1.2 1 0 0 1 1 1 1 Phosphofructokinase NAD_kinase PF01513.16 AIO00199.1 - 0.00062 18.6 0.0 0.001 17.9 0.0 1.3 1 0 0 1 1 1 1 ATP-NAD kinase Helicase_IV_N PF12462.3 AIO00199.1 - 0.12 12.0 0.1 0.19 11.3 0.1 1.3 1 0 0 1 1 1 0 DNA helicase IV / RNA helicase N terminal DUF3813 PF12758.2 AIO00199.1 - 0.19 11.9 2.1 0.2 11.7 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3813) zf-MIZ PF02891.15 AIO00200.1 - 7.9e-08 31.6 2.1 9.5e-08 31.4 0.0 2.2 3 0 0 3 3 3 1 MIZ/SP-RING zinc finger Nol1_Nop2_Fmu PF01189.12 AIO00202.1 - 2.2e-30 105.9 0.0 2.8e-29 102.4 0.0 2.0 1 1 0 1 1 1 1 NOL1/NOP2/sun family FtsJ PF01728.14 AIO00202.1 - 7e-06 26.1 0.0 1.8e-05 24.8 0.0 1.7 1 1 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_26 PF13659.1 AIO00202.1 - 0.00058 19.8 0.3 0.0015 18.5 0.1 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 AIO00202.1 - 0.026 14.1 0.0 0.06 12.9 0.0 1.6 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_18 PF12847.2 AIO00202.1 - 0.059 13.9 0.0 0.36 11.4 0.0 2.3 3 0 0 3 3 3 0 Methyltransferase domain Methyltransf_25 PF13649.1 AIO00202.1 - 0.08 13.3 0.0 0.17 12.2 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Bombolitin PF08096.6 AIO00202.1 - 0.32 11.1 1.3 0.7 10.0 0.9 1.6 1 0 0 1 1 1 0 Bombolitin family TPR_19 PF14559.1 AIO00203.1 - 6.2e-22 77.7 20.1 7.5e-05 22.9 1.4 9.2 7 2 2 9 9 9 7 Tetratricopeptide repeat TPR_14 PF13428.1 AIO00203.1 - 6.2e-17 60.5 36.4 0.00081 19.8 0.1 10.7 8 2 4 12 12 11 5 Tetratricopeptide repeat TPR_11 PF13414.1 AIO00203.1 - 9.8e-15 53.9 21.4 0.016 14.8 0.0 9.0 9 1 1 10 10 10 4 TPR repeat TPR_16 PF13432.1 AIO00203.1 - 7.1e-13 48.8 42.3 0.0032 18.0 1.6 10.7 9 2 2 11 11 10 6 Tetratricopeptide repeat TPR_2 PF07719.12 AIO00203.1 - 2.2e-09 36.5 22.0 0.15 12.0 0.0 11.5 12 0 0 12 12 12 2 Tetratricopeptide repeat TPR_12 PF13424.1 AIO00203.1 - 2.7e-08 33.6 24.8 0.0041 17.0 0.3 8.0 7 1 1 8 8 8 4 Tetratricopeptide repeat Apc3 PF12895.2 AIO00203.1 - 3.5e-07 30.2 14.3 0.069 13.2 0.2 6.2 5 1 1 6 6 6 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_1 PF00515.23 AIO00203.1 - 1.6e-05 24.3 3.2 0.52 10.0 0.0 6.7 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_6 PF13174.1 AIO00203.1 - 0.00025 21.2 17.7 0.18 12.3 0.0 8.7 10 0 0 10 10 10 1 Tetratricopeptide repeat TPR_17 PF13431.1 AIO00203.1 - 0.0018 18.2 13.5 46 4.5 0.0 8.6 9 0 0 9 9 8 0 Tetratricopeptide repeat HrpB1_HrpK PF09613.5 AIO00203.1 - 0.0029 17.1 0.5 0.0029 17.1 0.4 5.2 4 1 1 5 5 5 1 Bacterial type III secretion protein (HrpB1_HrpK) TPR_20 PF14561.1 AIO00203.1 - 0.0058 16.7 7.3 0.016 15.2 0.3 4.2 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_4 PF07721.9 AIO00203.1 - 0.012 15.9 39.1 0.39 11.2 0.5 10.1 9 0 0 9 9 8 0 Tetratricopeptide repeat Topoisom_bac PF01131.15 AIO00203.1 - 0.035 12.9 0.1 0.071 11.9 0.1 1.4 1 0 0 1 1 1 0 DNA topoisomerase Autophagy_N PF03986.8 AIO00203.1 - 0.13 12.0 0.5 0.23 11.1 0.3 1.3 1 0 0 1 1 1 0 Autophagocytosis associated protein (Atg3), N-terminal domain DUF4586 PF15239.1 AIO00204.1 - 7e-75 252.3 10.3 8.3e-75 252.1 7.2 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4586) Pkinase PF00069.20 AIO00205.1 - 3.4e-64 216.5 0.0 5.8e-64 215.7 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AIO00205.1 - 3.9e-45 153.9 0.0 1e-44 152.6 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 AIO00205.1 - 4.6e-07 29.0 0.0 9.2e-07 28.0 0.0 1.5 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 AIO00205.1 - 0.019 14.7 0.4 5.4 6.6 0.0 2.5 2 1 1 3 3 3 0 Phosphotransferase enzyme family Ribos_L4_asso_C PF14374.1 AIO00205.1 - 0.065 13.1 0.2 0.2 11.5 0.1 1.8 1 0 0 1 1 1 0 60S ribosomal protein L4 C-terminal domain Nucleoporin_FG PF13634.1 AIO00206.1 - 0.0037 17.4 4.4 0.0037 17.4 3.0 4.7 3 2 1 4 4 4 1 Nucleoporin FG repeat region DCX PF03607.12 AIO00207.1 - 5.3e-07 29.1 0.1 0.00027 20.4 0.0 2.6 2 0 0 2 2 2 2 Doublecortin PAP_central PF04928.12 AIO00208.1 - 7.5e-42 142.8 0.0 1e-41 142.4 0.0 1.1 1 0 0 1 1 1 1 Poly(A) polymerase central domain PAP_RNA-bind PF04926.10 AIO00208.1 - 2.6e-07 30.2 0.0 4.4e-07 29.5 0.0 1.3 1 0 0 1 1 1 1 Poly(A) polymerase predicted RNA binding domain NTP_transf_2 PF01909.18 AIO00208.1 - 0.0032 17.7 0.0 0.0061 16.8 0.0 1.5 1 0 0 1 1 1 1 Nucleotidyltransferase domain GAS PF13851.1 AIO00209.1 - 0.083 12.0 7.9 0.031 13.4 2.8 2.2 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding Noelin-1 PF12308.3 AIO00209.1 - 0.18 11.6 3.8 0.37 10.5 1.6 2.4 2 0 0 2 2 2 0 Neurogenesis glycoprotein NTR2 PF15458.1 AIO00209.1 - 7.3 5.7 11.2 5.8e+02 -0.5 7.7 2.7 1 1 0 1 1 1 0 Nineteen complex-related protein 2 SAM_1 PF00536.25 AIO00211.1 - 6.7e-05 22.9 0.0 0.00018 21.6 0.0 1.8 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.12 AIO00211.1 - 0.0061 16.3 0.0 0.017 14.9 0.0 1.9 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_PNT PF02198.11 AIO00211.1 - 0.028 14.1 0.0 0.068 12.9 0.0 1.6 1 0 0 1 1 1 0 Sterile alpha motif (SAM)/Pointed domain Proteasom_PSMB PF10508.4 AIO00212.1 - 0.0026 16.0 0.0 0.042 12.1 0.0 2.4 2 1 1 3 3 3 1 Proteasome non-ATPase 26S subunit Arm PF00514.18 AIO00212.1 - 0.0034 17.1 3.0 2.2 8.2 0.1 3.9 4 0 0 4 4 4 2 Armadillo/beta-catenin-like repeat Cnd3 PF12719.2 AIO00213.1 - 3.4e-45 154.3 0.5 3.4e-45 154.3 0.4 2.1 3 0 0 3 3 3 1 Nuclear condensing complex subunits, C-term domain HEAT_2 PF13646.1 AIO00213.1 - 6.9e-06 26.2 13.3 0.0051 17.0 0.1 6.0 4 2 1 5 5 5 2 HEAT repeats HEAT PF02985.17 AIO00213.1 - 0.00025 20.8 12.7 4.8 7.5 0.0 6.5 6 0 0 6 6 6 3 HEAT repeat Helicase_C_2 PF13307.1 AIO00214.1 - 2.9e-49 167.2 0.0 1.6e-48 164.8 0.0 2.1 2 0 0 2 2 2 1 Helicase C-terminal domain DEAD_2 PF06733.10 AIO00214.1 - 5.4e-44 149.6 0.2 1.4e-42 145.0 0.0 2.2 2 0 0 2 2 2 1 DEAD_2 DEAD PF00270.24 AIO00214.1 - 1.1e-05 25.0 0.0 0.0019 17.7 0.0 2.6 2 0 0 2 2 2 2 DEAD/DEAH box helicase ResIII PF04851.10 AIO00214.1 - 5.5e-05 23.0 0.0 0.0023 17.7 0.0 2.3 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_19 PF13245.1 AIO00214.1 - 0.017 14.8 0.1 0.081 12.6 0.0 2.2 1 0 0 1 1 1 0 Part of AAA domain AAA_11 PF13086.1 AIO00214.1 - 0.024 14.2 0.1 0.13 11.7 0.0 2.3 3 0 0 3 3 3 0 AAA domain Pkinase PF00069.20 AIO00215.1 - 3.4e-62 209.9 0.0 4.7e-62 209.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AIO00215.1 - 1.6e-40 138.8 0.0 2.4e-40 138.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 AIO00215.1 - 1.2e-05 24.4 0.0 5.7e-05 22.2 0.0 1.9 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 AIO00215.1 - 0.00022 21.0 0.0 0.064 12.9 0.0 2.4 1 1 1 2 2 2 2 Phosphotransferase enzyme family KdpD PF02702.12 AIO00215.1 - 0.046 12.8 0.1 0.083 12.0 0.1 1.3 1 0 0 1 1 1 0 Osmosensitive K+ channel His kinase sensor domain Ashwin PF15323.1 AIO00215.1 - 0.12 12.3 3.9 0.05 13.6 0.8 1.6 2 0 0 2 2 2 0 Developmental protein LCM PF04072.9 AIO00215.1 - 0.12 11.9 0.0 0.28 10.7 0.0 1.6 1 0 0 1 1 1 0 Leucine carboxyl methyltransferase PDEase_I PF00233.14 AIO00216.1 - 1.2e-38 133.2 0.0 3.8e-38 131.5 0.0 1.9 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase FYVE PF01363.16 AIO00216.1 - 2.4e-08 33.7 13.9 5e-08 32.7 9.6 1.5 1 0 0 1 1 1 1 FYVE zinc finger Glu-tRNAGln PF02686.10 AIO00216.1 - 0.11 12.3 2.1 0.33 10.7 0.2 3.0 3 0 0 3 3 3 0 Glu-tRNAGln amidotransferase C subunit DUF3584 PF12128.3 AIO00216.1 - 5.4 4.2 73.0 0.16 9.3 33.7 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) Esterase_phd PF10503.4 AIO00217.1 - 4.6 6.4 7.7 0.46 9.6 1.5 1.9 2 0 0 2 2 2 0 Esterase PHB depolymerase Beta_helix PF13229.1 AIO00219.1 - 2e-25 89.4 3.8 1.9e-15 56.9 0.6 2.1 1 1 1 2 2 2 2 Right handed beta helix region NosD PF05048.8 AIO00219.1 - 7.5e-11 41.6 0.0 9.7e-11 41.2 0.0 1.2 1 0 0 1 1 1 1 Periplasmic copper-binding protein (NosD) DUF1565 PF07602.6 AIO00219.1 - 0.088 11.9 0.1 4.1 6.4 0.1 2.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1565) Pkinase PF00069.20 AIO00220.1 - 1.3e-32 112.9 0.0 1.2e-30 106.4 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AIO00220.1 - 1.1e-15 57.3 0.0 2.5e-15 56.2 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 AIO00220.1 - 0.0038 16.3 0.0 0.0094 15.0 0.0 1.6 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 AIO00220.1 - 0.087 12.1 0.0 0.22 10.8 0.0 1.6 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL START PF01852.14 AIO00221.1 - 1.6e-25 89.6 0.0 2.3e-25 89.1 0.0 1.2 1 0 0 1 1 1 1 START domain DUF3074 PF11274.3 AIO00221.1 - 0.0012 18.4 0.0 0.0041 16.7 0.0 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF3074) Actin PF00022.14 AIO00222.1 - 1.7e-19 69.5 0.0 3.1e-13 48.9 0.0 2.3 1 1 0 2 2 2 2 Actin Ins_beta PF03488.9 AIO00223.1 - 0.031 14.0 0.5 0.053 13.3 0.3 1.4 1 0 0 1 1 1 0 Nematode insulin-related peptide beta type TPR_19 PF14559.1 AIO00224.1 - 1.8e-13 50.6 0.8 0.014 15.7 0.1 5.0 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_16 PF13432.1 AIO00224.1 - 9.6e-12 45.2 1.6 0.00018 22.0 0.0 4.4 4 0 0 4 4 4 3 Tetratricopeptide repeat Apc3 PF12895.2 AIO00224.1 - 1.3e-10 41.2 15.1 0.01 15.9 0.1 5.1 3 1 2 5 5 5 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_2 PF07719.12 AIO00224.1 - 3.4e-08 32.8 21.6 0.032 14.1 0.1 6.8 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_11 PF13414.1 AIO00224.1 - 2e-07 30.5 1.1 2e-07 30.5 0.7 4.5 4 1 1 5 5 5 1 TPR repeat TPR_14 PF13428.1 AIO00224.1 - 8.2e-06 26.0 3.6 2.5 8.9 0.1 5.2 4 1 1 5 5 4 2 Tetratricopeptide repeat TPR_1 PF00515.23 AIO00224.1 - 0.00018 20.9 16.1 0.11 12.1 0.2 5.1 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_7 PF13176.1 AIO00224.1 - 0.011 15.4 4.0 0.34 10.8 0.0 3.9 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.1 AIO00224.1 - 0.054 13.9 9.8 17 6.1 0.0 6.3 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_12 PF13424.1 AIO00224.1 - 0.087 12.7 15.9 0.29 11.0 0.3 5.7 4 2 1 5 5 5 0 Tetratricopeptide repeat TPR_17 PF13431.1 AIO00224.1 - 0.72 10.1 4.4 3.9 7.9 0.0 3.8 4 1 0 4 4 3 0 Tetratricopeptide repeat TPR_8 PF13181.1 AIO00224.1 - 4.2 7.3 15.8 14 5.7 0.1 5.7 7 0 0 7 7 7 0 Tetratricopeptide repeat Trypsin_2 PF13365.1 AIO00225.1 - 0.007 16.3 0.8 0.016 15.2 0.5 1.6 1 1 0 1 1 1 1 Trypsin-like peptidase domain Peptidase_C4 PF00863.14 AIO00225.1 - 0.036 13.0 0.0 0.054 12.4 0.0 1.2 1 0 0 1 1 1 0 Peptidase family C4 Mito_carr PF00153.22 AIO00226.1 - 1.5e-61 204.1 0.7 4.1e-21 74.4 0.0 3.1 2 1 1 3 3 3 3 Mitochondrial carrier protein DUF4131 PF13567.1 AIO00227.1 - 0.18 11.2 2.1 1.5 8.2 0.4 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) IU_nuc_hydro PF01156.14 AIO00228.1 - 1.9e-48 165.3 0.1 2.1e-48 165.1 0.1 1.0 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase LRR_6 PF13516.1 AIO00229.1 - 1.7e-25 86.1 23.8 0.0054 16.6 0.6 13.5 14 0 0 14 14 14 6 Leucine Rich repeat LRR_1 PF00560.28 AIO00229.1 - 4.8e-12 44.1 9.2 3.6 7.9 0.0 10.8 11 1 0 11 11 11 2 Leucine Rich Repeat LRR_4 PF12799.2 AIO00229.1 - 1.6e-10 40.3 10.4 0.87 9.2 0.1 6.9 4 2 3 7 7 7 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 AIO00229.1 - 2.8e-07 30.1 12.9 0.15 11.8 0.2 7.0 5 1 1 6 6 6 3 Leucine rich repeat LRR_7 PF13504.1 AIO00229.1 - 0.02 15.0 24.3 29 5.4 0.2 10.0 11 0 0 11 11 11 0 Leucine rich repeat DUF489 PF04356.7 AIO00229.1 - 0.037 13.6 0.8 0.091 12.3 0.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF489) AAA_13 PF13166.1 AIO00229.1 - 0.52 8.6 11.9 0.72 8.2 8.3 1.1 1 0 0 1 1 1 0 AAA domain RF-1 PF00472.15 AIO00229.1 - 1.5 8.6 10.2 0.38 10.5 0.2 2.6 2 0 0 2 2 2 0 RF-1 domain Fib_alpha PF08702.5 AIO00229.1 - 2.8 8.0 6.4 0.98 9.5 2.3 1.8 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family DUF1664 PF07889.7 AIO00229.1 - 4.1 7.2 8.5 11 5.8 2.1 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) YjcZ PF13990.1 AIO00230.1 - 0.062 12.4 0.0 0.13 11.3 0.0 1.5 1 0 0 1 1 1 0 YjcZ-like protein RRM_1 PF00076.17 AIO00231.1 - 1.8e-18 65.9 0.0 2.5e-18 65.4 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 AIO00231.1 - 3.4e-12 46.1 0.0 5.7e-12 45.4 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 AIO00231.1 - 7.6e-10 38.4 0.0 1.2e-09 37.8 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TFIIA PF03153.8 AIO00231.1 - 0.76 9.6 6.0 0.9 9.3 4.2 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF1738 PF08401.6 AIO00232.1 - 0.079 12.6 0.0 15 5.3 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1738) DUF4440 PF14534.1 AIO00233.1 - 0.1 12.8 0.0 0.19 11.9 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4440) Ribosomal_S19e PF01090.14 AIO00234.1 - 1.2e-45 154.4 0.0 1.4e-45 154.2 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S19e Mrr_N PF14338.1 AIO00234.1 - 0.12 12.4 0.0 0.23 11.5 0.0 1.4 1 0 0 1 1 1 0 Mrr N-terminal domain LRR_4 PF12799.2 AIO00236.1 - 5.2e-19 67.4 0.0 0.00032 20.2 0.0 8.7 4 2 6 10 10 10 7 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 AIO00236.1 - 8.8e-09 34.2 3.8 2.8 8.3 0.0 8.5 8 0 0 8 8 8 2 Leucine Rich Repeat LRR_7 PF13504.1 AIO00236.1 - 1e-05 24.9 9.9 1.9 9.0 0.1 7.7 6 1 1 7 7 7 2 Leucine rich repeat LRR_6 PF13516.1 AIO00236.1 - 0.00022 20.9 1.6 46 4.5 0.0 6.2 5 0 0 5 5 5 0 Leucine Rich repeat Abhydrolase_6 PF12697.2 AIO00238.1 - 3.3e-15 56.6 1.3 5.6e-15 55.8 0.9 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 AIO00238.1 - 1.3e-06 28.2 0.0 2.6e-06 27.2 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 AIO00238.1 - 0.00041 19.9 0.0 0.0015 18.1 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Pro_isomerase PF00160.16 AIO00239.1 - 7.8e-20 71.6 0.0 1.2e-19 70.9 0.0 1.3 1 1 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD UPF0220 PF05255.6 AIO00241.1 - 1.5e-18 66.6 0.6 3e-18 65.6 0.4 1.4 1 1 0 1 1 1 1 Uncharacterised protein family (UPF0220) PIRT PF15099.1 AIO00241.1 - 1.3 8.2 3.5 0.68 9.1 0.4 1.9 2 1 0 2 2 2 0 Phosphoinositide-interacting protein family MATH PF00917.21 AIO00242.1 - 6.4e-06 26.4 0.2 1.9e-05 24.8 0.1 1.9 1 0 0 1 1 1 1 MATH domain Mnd1 PF03962.10 AIO00242.1 - 4.3 6.9 40.9 10 5.6 21.8 3.2 2 1 0 2 2 2 0 Mnd1 family DCP1 PF06058.8 AIO00243.1 - 0.089 12.8 0.0 14 5.7 0.0 2.5 2 0 0 2 2 2 0 Dcp1-like decapping family NblA PF04485.7 AIO00243.1 - 0.14 12.0 0.6 12 5.8 0.0 2.9 3 0 0 3 3 3 0 Phycobilisome degradation protein nblA Cyclin_N PF00134.18 AIO00245.1 - 2.8e-24 85.0 0.2 6.4e-24 83.9 0.1 1.6 1 0 0 1 1 1 1 Cyclin, N-terminal domain FoP_duplication PF13865.1 AIO00246.1 - 5.3e-06 26.7 1.8 5.3e-06 26.7 1.2 4.5 2 1 3 5 5 5 1 C-terminal duplication domain of Friend of PRMT1 LRR_4 PF12799.2 AIO00248.1 - 4.3e-07 29.4 13.8 0.00049 19.6 0.3 4.9 4 2 1 5 5 5 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 AIO00248.1 - 1.1e-05 25.0 17.2 0.0064 16.2 0.7 5.2 4 2 1 5 5 5 3 Leucine rich repeat LRR_6 PF13516.1 AIO00248.1 - 4.5e-05 23.0 8.4 0.22 11.6 0.0 5.8 6 0 0 6 6 6 2 Leucine Rich repeat LRR_1 PF00560.28 AIO00248.1 - 0.00026 20.6 12.8 3.8 7.8 0.0 6.0 5 1 1 6 6 6 3 Leucine Rich Repeat FAD-oxidase_C PF02913.14 AIO00249.1 - 2e-49 168.1 0.0 7.3e-49 166.3 0.0 1.8 2 0 0 2 2 2 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.18 AIO00249.1 - 1.8e-38 131.1 0.0 4.5e-38 129.8 0.0 1.6 2 0 0 2 2 2 1 FAD binding domain Phage_cap_E PF03864.10 AIO00249.1 - 0.043 12.7 0.0 0.074 11.9 0.0 1.3 1 0 0 1 1 1 0 Phage major capsid protein E tRNA-synt_2 PF00152.15 AIO00250.1 - 4e-86 288.8 0.0 5e-86 288.5 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA-synt_2d PF01409.15 AIO00250.1 - 2.6e-07 30.0 0.2 0.00017 20.8 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) tRNA_anti-codon PF01336.20 AIO00250.1 - 1.4e-06 28.0 0.0 2.6e-06 27.1 0.0 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2b PF00587.20 AIO00250.1 - 0.049 13.2 0.1 1.5 8.3 0.1 2.3 2 0 0 2 2 2 0 tRNA synthetase class II core domain (G, H, P, S and T) Yip1 PF04893.12 AIO00251.1 - 4.4e-11 42.5 14.4 7.7e-11 41.7 9.8 1.5 1 1 0 1 1 1 1 Yip1 domain LRR_6 PF13516.1 AIO00252.1 - 2.3e-29 98.1 7.8 7.4e-07 28.6 0.0 8.4 9 0 0 9 9 9 6 Leucine Rich repeat LRR_4 PF12799.2 AIO00252.1 - 3e-14 52.2 6.1 3.3e-05 23.3 0.2 5.4 4 2 1 5 5 5 5 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 AIO00252.1 - 7.1e-11 40.5 2.4 0.38 10.9 0.0 8.4 9 0 0 9 9 9 2 Leucine Rich Repeat LRR_8 PF13855.1 AIO00252.1 - 4e-07 29.7 11.3 0.024 14.3 1.2 5.5 3 3 2 5 5 5 3 Leucine rich repeat LRR_7 PF13504.1 AIO00252.1 - 4.7e-06 25.9 12.1 0.2 11.9 0.1 8.2 9 0 0 9 9 9 1 Leucine rich repeat Rubis-subs-bind PF09273.6 AIO00253.1 - 5.2e-11 42.5 0.1 2.2e-10 40.5 0.0 2.1 2 1 0 2 2 2 1 Rubisco LSMT substrate-binding SET PF00856.23 AIO00253.1 - 0.13 12.5 0.0 0.21 11.9 0.0 1.5 1 0 0 1 1 1 0 SET domain NAD_binding_2 PF03446.10 AIO00254.1 - 2.1e-53 180.5 1.2 3.6e-53 179.7 0.8 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.1 AIO00254.1 - 9.4e-35 119.3 0.1 1.5e-34 118.6 0.1 1.3 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 2-Hacid_dh_C PF02826.14 AIO00254.1 - 0.00016 20.8 0.0 0.00036 19.7 0.0 1.6 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain F420_oxidored PF03807.12 AIO00254.1 - 0.00037 20.8 1.1 0.0012 19.2 0.1 2.4 3 0 0 3 3 2 1 NADP oxidoreductase coenzyme F420-dependent UDPG_MGDP_dh_N PF03721.9 AIO00254.1 - 0.0006 19.2 0.0 0.36 10.1 0.0 2.5 1 1 0 2 2 2 2 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 3HCDH_N PF02737.13 AIO00254.1 - 0.0015 18.2 0.1 0.0035 17.0 0.0 1.8 1 1 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Shikimate_DH PF01488.15 AIO00254.1 - 0.016 15.3 0.0 0.03 14.3 0.0 1.6 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase IlvN PF07991.7 AIO00254.1 - 0.021 14.1 0.3 0.047 13.0 0.0 1.7 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, catalytic domain NAD_Gly3P_dh_N PF01210.18 AIO00254.1 - 0.077 12.7 0.5 0.48 10.1 0.0 2.4 3 0 0 3 3 3 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Nrf1_activ_bdg PF10492.4 AIO00254.1 - 0.078 13.4 1.1 28 5.2 0.0 3.0 3 0 0 3 3 3 0 Nrf1 activator activation site binding domain ApbA PF02558.11 AIO00254.1 - 0.095 12.1 0.0 0.17 11.3 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA MAGE_N PF12440.3 AIO00255.1 - 0.013 15.7 1.2 0.013 15.7 0.8 2.2 2 0 0 2 2 2 0 Melanoma associated antigen family N terminal Gly-zipper_OmpA PF13436.1 AIO00256.1 - 0.00066 19.3 2.2 0.00093 18.8 1.5 1.2 1 0 0 1 1 1 1 Glycine-zipper containing OmpA-like membrane domain Gly-zipper_Omp PF13488.1 AIO00256.1 - 0.11 12.1 6.8 0.17 11.5 4.7 1.3 1 0 0 1 1 1 0 Glycine zipper Rick_17kDa_Anti PF05433.10 AIO00256.1 - 2.5 7.8 8.9 5.7 6.6 6.2 1.6 1 1 0 1 1 1 0 Glycine zipper 2TM domain Bacteriocin_IIc PF10439.4 AIO00256.1 - 3.5 7.8 10.5 6 7.0 7.3 1.3 1 0 0 1 1 1 0 Bacteriocin class II with double-glycine leader peptide Gly-zipper_YMGG PF13441.1 AIO00256.1 - 10 5.7 10.2 0.36 10.3 1.4 2.0 1 1 0 1 1 1 0 YMGG-like Gly-zipper RrnaAD PF00398.15 AIO00257.1 - 4.9e-59 199.4 0.0 6.4e-59 199.1 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_26 PF13659.1 AIO00257.1 - 2.2e-09 37.3 0.0 4.8e-09 36.2 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 AIO00257.1 - 3.3e-06 27.6 0.0 5.6e-06 26.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 AIO00257.1 - 6.8e-06 25.7 0.0 9.9e-06 25.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 AIO00257.1 - 0.00011 22.5 0.0 0.00021 21.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 AIO00257.1 - 0.00028 20.3 0.0 0.00052 19.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_23 PF13489.1 AIO00257.1 - 0.00044 20.0 0.0 0.00072 19.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 AIO00257.1 - 0.0018 18.7 0.0 0.0035 17.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 AIO00257.1 - 0.0072 15.3 0.0 0.012 14.6 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase PCMT PF01135.14 AIO00257.1 - 0.015 14.8 0.0 0.023 14.2 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_25 PF13649.1 AIO00257.1 - 0.017 15.4 0.0 0.029 14.7 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase domain LELP1 PF15042.1 AIO00257.1 - 0.036 14.2 1.7 1.3 9.1 0.9 2.3 2 0 0 2 2 2 0 Late cornified envelope-like proline-rich protein 1 DREV PF05219.7 AIO00257.1 - 0.039 12.8 0.0 0.07 11.9 0.0 1.3 1 0 0 1 1 1 0 DREV methyltransferase Methyltransf_28 PF02636.12 AIO00257.1 - 0.042 13.2 0.0 0.062 12.6 0.0 1.2 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Ubie_methyltran PF01209.13 AIO00257.1 - 0.1 11.6 0.0 0.19 10.8 0.0 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family zf-RanBP PF00641.13 AIO00258.1 - 0.0032 16.5 5.9 0.0032 16.5 4.1 1.8 2 0 0 2 2 2 1 Zn-finger in Ran binding protein and others Mito_carr PF00153.22 AIO00259.1 - 9.8e-14 50.8 0.1 1.3e-08 34.4 0.0 2.4 2 0 0 2 2 2 2 Mitochondrial carrier protein RNase_T PF00929.19 AIO00261.1 - 3.4e-22 79.4 0.0 6.7e-22 78.5 0.0 1.6 1 0 0 1 1 1 1 Exonuclease UCH_1 PF13423.1 AIO00261.1 - 1.2e-21 77.4 0.0 1.4e-20 73.9 0.0 2.4 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-C2H2 PF00096.21 AIO00262.1 - 1.9e-12 46.7 50.1 0.0032 17.6 0.1 8.4 8 0 0 8 8 8 6 Zinc finger, C2H2 type zf-Di19 PF05605.7 AIO00262.1 - 3.5e-12 46.2 31.8 0.002 18.2 1.0 7.2 7 0 0 7 7 7 4 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_4 PF13894.1 AIO00262.1 - 2.6e-09 36.7 48.4 0.0053 17.0 0.2 8.3 8 0 0 8 8 8 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 AIO00262.1 - 9.9e-07 28.7 23.3 0.04 14.0 0.1 6.4 6 1 0 6 6 6 3 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 AIO00262.1 - 3.8e-06 26.9 13.8 0.38 11.0 0.4 5.9 5 0 0 5 5 5 3 Zinc-finger of C2H2 type Lar_restr_allev PF14354.1 AIO00262.1 - 0.0013 19.0 6.7 0.14 12.5 0.2 4.0 5 0 0 5 5 4 2 Restriction alleviation protein Lar DUF629 PF04780.7 AIO00262.1 - 0.0038 15.8 9.3 7 5.0 0.0 5.5 5 1 1 6 6 6 0 Protein of unknown function (DUF629) zf-H2C2_2 PF13465.1 AIO00262.1 - 0.031 14.5 29.8 0.12 12.7 0.1 7.7 9 0 0 9 9 8 0 Zinc-finger double domain SprT-like PF10263.4 AIO00262.1 - 0.053 13.1 1.4 0.35 10.5 1.0 2.3 1 1 0 1 1 1 0 SprT-like family zf-C2HC_2 PF13913.1 AIO00262.1 - 0.057 13.1 17.2 0.039 13.6 0.7 5.3 5 0 0 5 5 5 0 zinc-finger of a C2HC-type DUF1805 PF08827.6 AIO00262.1 - 0.073 12.8 0.0 0.2 11.5 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1805) zf-met2 PF12907.2 AIO00262.1 - 0.11 12.4 20.3 0.11 12.4 0.2 5.3 6 1 0 6 6 5 0 Zinc-binding zf-C2H2_6 PF13912.1 AIO00262.1 - 0.14 12.0 28.4 0.2 11.5 0.1 6.4 7 0 0 7 7 7 0 C2H2-type zinc finger zf-C2H2_2 PF12756.2 AIO00262.1 - 0.18 11.9 23.9 0.71 10.0 0.3 6.6 5 2 2 7 7 7 0 C2H2 type zinc-finger (2 copies) zf-TFIIB PF13453.1 AIO00262.1 - 0.22 10.7 13.4 1.4 8.1 0.3 4.0 4 0 0 4 4 4 0 Transcription factor zinc-finger OrfB_Zn_ribbon PF07282.6 AIO00262.1 - 0.25 11.0 2.7 4 7.1 0.1 3.4 3 0 0 3 3 3 0 Putative transposase DNA-binding domain zf-H2C2_5 PF13909.1 AIO00262.1 - 0.66 10.3 0.1 0.66 10.3 0.0 6.2 7 0 0 7 7 6 0 C2H2-type zinc-finger domain DZR PF12773.2 AIO00262.1 - 1.8 8.4 15.0 0.55 10.0 0.1 4.6 4 1 1 5 5 5 0 Double zinc ribbon zinc_ribbon_2 PF13240.1 AIO00262.1 - 2.2 7.8 6.2 5.9 6.5 0.1 3.6 3 0 0 3 3 3 0 zinc-ribbon domain C1_4 PF07975.7 AIO00262.1 - 2.4 8.2 19.1 3.8 7.6 0.3 5.3 6 0 0 6 6 5 0 TFIIH C1-like domain IBR PF01485.16 AIO00262.1 - 2.5 8.0 10.7 25 4.8 0.2 3.9 4 0 0 4 4 3 0 IBR domain zf-RING_3 PF14369.1 AIO00262.1 - 3.2 7.8 18.0 4.2 7.4 0.2 5.5 5 1 0 5 5 5 0 zinc-finger zf-ribbon_3 PF13248.1 AIO00262.1 - 5.4 6.3 8.8 9.1 5.6 0.1 4.0 4 0 0 4 4 4 0 zinc-ribbon domain Peptidase_C54 PF03416.14 AIO00263.1 - 1.4e-38 132.6 0.1 1.4e-37 129.3 0.1 1.9 1 1 0 1 1 1 1 Peptidase family C54 Peptidase_C78 PF07910.8 AIO00263.1 - 0.024 13.7 0.0 0.074 12.1 0.0 1.7 2 0 0 2 2 2 0 Peptidase family C78 LIM PF00412.17 AIO00264.1 - 4.1e-05 23.5 12.6 4.5e-05 23.4 6.2 2.4 2 1 0 2 2 2 1 LIM domain zf-PARP PF00645.13 AIO00264.1 - 0.0019 18.3 1.9 0.18 12.0 0.7 2.6 2 1 0 2 2 2 1 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region NCD3G PF07562.9 AIO00264.1 - 0.068 12.8 6.3 1.6 8.4 1.2 2.5 2 0 0 2 2 2 0 Nine Cysteines Domain of family 3 GPCR WHIM2 PF15613.1 AIO00264.1 - 0.21 11.5 1.0 0.54 10.2 0.1 2.1 2 0 0 2 2 2 0 WSTF, HB1, Itc1p, MBD9 motif 2 Sad1_UNC PF07738.8 AIO00268.1 - 3e-19 69.1 0.0 4.8e-19 68.4 0.0 1.3 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal ATG16 PF08614.6 AIO00268.1 - 0.065 13.0 2.1 0.11 12.3 1.4 1.2 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) Exonuc_VII_L PF02601.10 AIO00268.1 - 0.19 10.8 0.8 0.32 10.1 0.5 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit IncA PF04156.9 AIO00268.1 - 4.8 6.7 10.8 0.82 9.2 1.6 2.4 2 0 0 2 2 2 0 IncA protein FAM104 PF15434.1 AIO00269.1 - 0.28 11.3 2.9 0.29 11.3 0.0 2.0 1 1 1 2 2 2 0 Family 104 SOG2 PF10428.4 AIO00269.1 - 0.87 8.1 10.4 1.1 7.8 7.2 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein Ku PF02735.11 AIO00270.1 - 4.4e-13 49.0 0.0 7.1e-13 48.4 0.0 1.3 1 0 0 1 1 1 1 Ku70/Ku80 beta-barrel domain Ku_PK_bind PF08785.6 AIO00270.1 - 4.4e-13 49.1 0.1 1.7e-12 47.2 0.0 2.0 2 0 0 2 2 2 1 Ku C terminal domain like Ku_N PF03731.10 AIO00270.1 - 8.7e-11 41.6 0.0 1.5e-10 40.9 0.0 1.3 1 0 0 1 1 1 1 Ku70/Ku80 N-terminal alpha/beta domain Ku_C PF03730.9 AIO00270.1 - 0.0013 19.2 0.1 0.0029 18.0 0.1 1.5 1 0 0 1 1 1 1 Ku70/Ku80 C-terminal arm Kinesin PF00225.18 AIO00271.1 - 1.8e-89 299.7 1.2 2.7e-89 299.1 0.8 1.2 1 0 0 1 1 1 1 Kinesin motor domain TSC22 PF01166.13 AIO00271.1 - 0.00034 20.5 4.3 0.0023 17.8 0.0 2.8 2 0 0 2 2 2 1 TSC-22/dip/bun family PIF1 PF05970.9 AIO00271.1 - 0.012 14.5 0.2 0.025 13.5 0.1 1.5 1 0 0 1 1 1 0 PIF1-like helicase AAA_16 PF13191.1 AIO00271.1 - 0.032 14.2 0.1 0.17 11.8 0.0 2.1 2 1 0 2 2 2 0 AAA ATPase domain AAA_22 PF13401.1 AIO00271.1 - 0.062 13.4 0.7 0.35 11.0 0.1 2.6 3 1 0 3 3 3 0 AAA domain DUF972 PF06156.8 AIO00271.1 - 0.16 12.2 0.1 0.16 12.2 0.1 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF972) EMP70 PF02990.11 AIO00272.1 - 4.2e-137 457.7 7.4 4.2e-137 457.7 5.2 1.3 1 1 0 1 1 1 1 Endomembrane protein 70 Pkinase PF00069.20 AIO00273.1 - 5.9e-59 199.3 0.0 7.7e-59 198.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AIO00273.1 - 1.8e-26 92.7 0.0 2.5e-26 92.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 AIO00273.1 - 5.6e-06 25.5 0.0 0.00017 20.6 0.0 2.1 2 0 0 2 2 2 1 Kinase-like DUF3455 PF11937.3 AIO00273.1 - 0.11 12.4 0.0 0.18 11.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3455) Seadorna_VP7 PF07387.6 AIO00273.1 - 0.16 10.7 0.0 0.27 10.0 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 PP2C PF00481.16 AIO00274.1 - 1.1e-49 169.1 0.2 1.5e-49 168.6 0.1 1.1 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.1 AIO00274.1 - 1.3e-05 24.6 0.1 6.2e-05 22.4 0.0 2.1 1 1 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.7 AIO00274.1 - 0.00012 21.8 0.0 0.00055 19.6 0.0 2.0 1 1 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) Shisa PF13908.1 AIO00275.1 - 0.013 15.6 1.3 0.021 15.0 0.6 1.6 1 1 0 1 1 1 0 Wnt and FGF inhibitory regulator GPS PF01825.16 AIO00275.1 - 6.3 6.9 7.1 1.3 9.1 0.1 2.6 3 0 0 3 3 3 0 Latrophilin/CL-1-like GPS domain Abhydrolase_5 PF12695.2 AIO00276.1 - 5.7e-14 52.0 0.0 9.5e-14 51.3 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 AIO00276.1 - 1.8e-12 47.6 0.0 2.6e-12 47.0 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S15 PF02129.13 AIO00276.1 - 1.6e-07 31.0 0.0 7.5e-07 28.8 0.0 1.8 1 1 1 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_1 PF00561.15 AIO00276.1 - 7.5e-06 25.6 0.3 0.088 12.3 0.0 2.2 1 1 0 2 2 2 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 AIO00276.1 - 2.4e-05 23.6 0.1 0.00041 19.6 0.0 2.1 1 1 0 1 1 1 1 Prolyl oligopeptidase family PhoPQ_related PF10142.4 AIO00276.1 - 0.0038 15.7 0.0 0.0049 15.4 0.0 1.1 1 0 0 1 1 1 1 PhoPQ-activated pathogenicity-related protein Hydrolase_4 PF12146.3 AIO00276.1 - 0.015 15.1 0.0 0.034 13.9 0.0 1.6 1 0 0 1 1 1 0 Putative lysophospholipase AXE1 PF05448.7 AIO00276.1 - 0.018 13.5 0.1 0.78 8.1 0.0 2.4 1 1 1 2 2 2 0 Acetyl xylan esterase (AXE1) Esterase PF00756.15 AIO00276.1 - 0.034 13.5 0.0 0.049 13.0 0.0 1.2 1 0 0 1 1 1 0 Putative esterase FSH1 PF03959.8 AIO00276.1 - 0.064 12.6 0.0 0.13 11.6 0.0 1.5 1 1 0 1 1 1 0 Serine hydrolase (FSH1) BAAT_C PF08840.6 AIO00276.1 - 0.19 11.4 0.0 0.38 10.4 0.0 1.4 1 1 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal PAP2 PF01569.16 AIO00277.1 - 8.1e-21 74.0 1.7 1.3e-20 73.3 1.2 1.3 1 0 0 1 1 1 1 PAP2 superfamily TM2 PF05154.11 AIO00277.1 - 0.0037 17.4 2.5 0.0082 16.3 1.8 1.7 1 0 0 1 1 1 1 TM2 domain Polysacc_synt PF01943.12 AIO00277.1 - 0.016 14.4 0.5 0.029 13.6 0.3 1.5 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein WD40 PF00400.27 AIO00278.1 - 2.9e-41 137.8 11.2 9.4e-13 47.5 0.3 7.0 7 0 0 7 7 7 5 WD domain, G-beta repeat Nucleoporin_N PF08801.6 AIO00278.1 - 0.046 12.4 0.0 0.082 11.6 0.0 1.3 1 0 0 1 1 1 0 Nup133 N terminal like TFIIIC_delta PF12657.2 AIO00278.1 - 0.1 12.3 0.3 11 5.6 0.0 3.2 3 1 0 3 3 3 0 Transcription factor IIIC subunit delta N-term DAGK_cat PF00781.19 AIO00279.1 - 3.1e-11 42.8 0.0 5e-11 42.1 0.0 1.3 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain Evr1_Alr PF04777.8 AIO00280.1 - 1.7e-14 53.4 0.1 5.1e-14 51.9 0.0 1.9 2 0 0 2 2 2 1 Erv1 / Alr family Thioredoxin PF00085.15 AIO00280.1 - 4.5e-08 32.7 0.0 9.9e-08 31.6 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin DUF3693 PF12472.3 AIO00280.1 - 0.019 14.5 0.1 0.088 12.4 0.1 2.1 1 0 0 1 1 1 0 Phage related protein RRF PF01765.14 AIO00281.1 - 3e-12 46.3 2.5 5.1e-12 45.5 0.5 1.9 1 1 1 2 2 2 1 Ribosome recycling factor Activator-TraM PF11657.3 AIO00281.1 - 0.044 13.2 1.5 0.23 10.9 0.1 2.2 2 0 0 2 2 2 0 Transcriptional activator TraM IF4E PF01652.13 AIO00282.1 - 2.4e-31 108.4 0.0 3.3e-31 108.0 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E PAM2 PF07145.10 AIO00282.1 - 0.18 11.4 2.3 0.19 11.2 0.1 2.1 2 0 0 2 2 2 0 Ataxin-2 C-terminal region tRNA-synt_2 PF00152.15 AIO00283.1 - 2.5e-72 243.4 0.0 4.1e-72 242.7 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 AIO00283.1 - 1.4e-08 34.4 0.4 2.4e-08 33.6 0.3 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.15 AIO00283.1 - 0.0001 21.6 0.6 0.44 9.6 0.1 2.5 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) EspB PF05802.6 AIO00283.1 - 0.05 12.5 1.4 0.093 11.6 1.0 1.4 1 0 0 1 1 1 0 Enterobacterial EspB protein Metal_resist PF13801.1 AIO00284.1 - 0.0064 16.4 1.0 0.38 10.7 0.0 3.1 3 0 0 3 3 3 1 Heavy-metal resistance Bystin PF05291.6 AIO00285.1 - 3.1e-109 364.5 0.7 4.7e-109 363.9 0.5 1.1 1 0 0 1 1 1 1 Bystin DUF3299 PF11736.3 AIO00285.1 - 0.0014 18.4 0.2 0.041 13.7 0.0 2.5 2 1 0 2 2 2 1 Protein of unknown function (DUF3299) cIII PF08134.6 AIO00285.1 - 0.09 12.3 0.2 0.18 11.3 0.1 1.5 1 0 0 1 1 1 0 cIII protein family SelA PF03841.8 AIO00286.1 - 0.54 8.9 3.3 0.86 8.2 2.3 1.2 1 0 0 1 1 1 0 L-seryl-tRNA selenium transferase LRR_4 PF12799.2 AIO00288.1 - 1.1e-09 37.6 0.7 2.6e-06 26.9 0.0 3.4 3 0 0 3 3 3 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 AIO00288.1 - 1.7e-05 24.4 0.3 0.00011 21.9 0.0 2.4 2 0 0 2 2 2 1 Leucine rich repeat LRR_6 PF13516.1 AIO00288.1 - 0.028 14.4 0.8 2.9 8.2 0.0 4.0 4 0 0 4 4 4 0 Leucine Rich repeat LRR_1 PF00560.28 AIO00288.1 - 0.058 13.4 3.0 30 5.1 0.0 4.7 4 1 0 4 4 4 0 Leucine Rich Repeat LRR_7 PF13504.1 AIO00288.1 - 0.41 11.0 4.6 39 5.0 0.1 4.8 4 0 0 4 4 4 0 Leucine rich repeat NatB_MDM20 PF09797.4 AIO00289.1 - 6.8e-71 238.9 0.1 1.9e-70 237.4 0.0 1.8 2 0 0 2 2 2 1 N-acetyltransferase B complex (NatB) non catalytic subunit TPR_14 PF13428.1 AIO00289.1 - 0.011 16.2 13.1 0.1 13.3 0.4 5.9 4 2 1 5 5 5 0 Tetratricopeptide repeat TPR_19 PF14559.1 AIO00289.1 - 0.32 11.3 13.2 1.4 9.2 0.2 4.2 3 1 0 3 3 3 0 Tetratricopeptide repeat Alg14 PF08660.6 AIO00290.1 - 7.8e-52 175.6 0.0 1.2e-51 175.1 0.0 1.2 1 0 0 1 1 1 1 Oligosaccharide biosynthesis protein Alg14 like Glyco_tran_28_C PF04101.11 AIO00290.1 - 1.8e-19 69.9 0.0 4.5e-19 68.7 0.0 1.6 1 1 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Glyco_trans_1_3 PF13528.1 AIO00290.1 - 0.0041 16.3 0.0 0.011 14.9 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferase family 1 RRM_1 PF00076.17 AIO00291.1 - 2.2e-16 59.2 0.0 3.3e-16 58.6 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 AIO00291.1 - 1.2e-12 47.6 0.0 1.7e-12 47.0 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 AIO00291.1 - 3.4e-09 36.4 0.0 4.9e-09 35.9 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) LMBR1 PF04791.11 AIO00292.1 - 5.3e-28 97.8 26.5 1.2e-27 96.6 18.4 1.6 1 1 0 1 1 1 1 LMBR1-like membrane protein DUF962 PF06127.6 AIO00292.1 - 2.9 7.8 9.0 17 5.3 0.1 3.7 3 0 0 3 3 3 0 Protein of unknown function (DUF962) HEAT_EZ PF13513.1 AIO00293.1 - 0.034 14.6 1.1 0.13 12.7 0.0 2.6 3 1 1 4 4 4 0 HEAT-like repeat HrpA_pilin PF09589.5 AIO00293.1 - 0.1 12.9 1.3 3.5 8.0 0.2 2.8 1 1 0 2 2 2 0 HrpA pilus formation protein PSP PF04046.11 AIO00294.1 - 3.5e-20 71.1 4.7 8.4e-20 69.8 3.2 1.7 1 0 0 1 1 1 1 PSP DUF382 PF04037.8 AIO00294.1 - 1.6e-11 44.1 0.0 1.6e-11 44.1 0.0 2.5 3 0 0 3 3 3 1 Domain of unknown function (DUF382) CAP18_C PF12153.3 AIO00294.1 - 0.25 11.0 1.5 0.5 10.0 1.0 1.4 1 0 0 1 1 1 0 LPS binding domain of CAP18 (C terminal) Spore_coat_CotO PF14153.1 AIO00294.1 - 6.3 6.1 9.5 1.2e+02 2.0 0.0 2.3 2 0 0 2 2 2 0 Spore coat protein CotO AMP-binding PF00501.23 AIO00295.1 - 1.4e-25 89.5 0.1 5.1e-12 44.9 0.0 2.1 2 0 0 2 2 2 2 AMP-binding enzyme BBS2_C PF14782.1 AIO00296.1 - 7.7e-138 459.6 0.0 1.1e-137 459.2 0.0 1.2 1 0 0 1 1 1 1 Ciliary BBSome complex subunit 2, C-terminal BBS2_Mid PF14783.1 AIO00296.1 - 1e-27 96.0 0.0 5.5e-27 93.7 0.0 2.3 2 1 0 2 2 2 1 Ciliary BBSome complex subunit 2, middle region BBS2_N PF14781.1 AIO00296.1 - 3.1e-10 39.8 0.0 9e-10 38.3 0.0 1.8 1 0 0 1 1 1 1 Ciliary BBSome complex subunit 2, N-terminal FG-GAP PF01839.18 AIO00296.1 - 8e-05 22.2 0.8 0.00023 20.7 0.6 1.8 1 0 0 1 1 1 1 FG-GAP repeat VCBS PF13517.1 AIO00296.1 - 0.0015 18.8 0.1 0.0036 17.6 0.1 1.7 1 0 0 1 1 1 1 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FlgN PF05130.7 AIO00296.1 - 0.011 15.9 0.9 0.011 15.9 0.6 2.6 2 1 0 2 2 2 0 FlgN protein Pkinase PF00069.20 AIO00297.1 - 6.5e-64 215.5 0.0 8.4e-64 215.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AIO00297.1 - 9.1e-41 139.6 0.0 1.3e-40 139.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 AIO00297.1 - 0.0014 17.6 0.0 0.0032 16.4 0.0 1.5 2 0 0 2 2 2 1 Kinase-like Cyt-b5 PF00173.23 AIO00298.1 - 5.4e-29 99.8 0.0 1e-17 63.6 0.0 2.4 2 0 0 2 2 2 2 Cytochrome b5-like Heme/Steroid binding domain NAD_binding_1 PF00175.16 AIO00298.1 - 6.1e-11 42.8 0.0 1.3e-10 41.8 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 AIO00298.1 - 0.00078 19.5 0.0 0.002 18.1 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.7 AIO00298.1 - 0.0027 17.6 0.0 0.01 15.7 0.0 1.9 2 0 0 2 2 2 1 Ferric reductase NAD binding domain RRS1 PF04939.7 AIO00299.1 - 6.4e-48 162.3 4.4 6.4e-48 162.3 3.0 1.4 2 0 0 2 2 2 1 Ribosome biogenesis regulatory protein (RRS1) SCP1201-deam PF14428.1 AIO00299.1 - 0.24 11.0 1.8 0.5 10.0 0.8 1.9 2 1 0 2 2 2 0 SCP1.201-like deaminase tRNA-synt_His PF13393.1 AIO00300.1 - 7.2e-42 143.5 0.0 1e-41 143.0 0.0 1.2 1 0 0 1 1 1 1 Histidyl-tRNA synthetase tRNA-synt_2b PF00587.20 AIO00300.1 - 2.9e-16 59.5 0.0 4.8e-16 58.8 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 AIO00300.1 - 1.9e-06 27.6 0.1 5.2e-06 26.3 0.1 1.7 1 0 0 1 1 1 1 Anticodon binding domain DUF4473 PF14747.1 AIO00300.1 - 0.056 13.6 0.0 0.16 12.1 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4473) PDZ_2 PF13180.1 AIO00303.1 - 2.2e-11 43.4 0.0 1e-10 41.3 0.0 2.1 2 0 0 2 2 2 1 PDZ domain PI-PLC-X PF00388.14 AIO00303.1 - 5.4e-06 25.8 0.0 1.1e-05 24.8 0.0 1.5 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PDZ PF00595.19 AIO00303.1 - 8.4e-06 25.8 0.0 1.7e-05 24.8 0.0 1.5 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) EF-hand_like PF09279.6 AIO00303.1 - 4.5e-05 23.3 0.4 0.00017 21.5 0.3 1.9 1 0 0 1 1 1 1 Phosphoinositide-specific phospholipase C, efhand-like PI-PLC-Y PF00387.14 AIO00303.1 - 0.11 12.5 0.0 0.36 10.8 0.0 1.8 1 0 0 1 1 1 0 Phosphatidylinositol-specific phospholipase C, Y domain Ribosomal_S30 PF04758.9 AIO00304.1 - 1.7e-27 94.9 6.8 1.9e-27 94.7 4.7 1.0 1 0 0 1 1 1 1 Ribosomal protein S30 DUF1390 PF07150.6 AIO00304.1 - 0.092 12.0 0.3 0.097 12.0 0.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1390) Ribosomal_S30 PF04758.9 AIO00305.1 - 1.2e-27 95.3 7.1 1.4e-27 95.1 4.9 1.0 1 0 0 1 1 1 1 Ribosomal protein S30 Ribosomal_S30 PF04758.9 AIO00306.1 - 1.7e-27 94.9 6.8 1.9e-27 94.7 4.7 1.0 1 0 0 1 1 1 1 Ribosomal protein S30 DUF1390 PF07150.6 AIO00306.1 - 0.092 12.0 0.3 0.097 12.0 0.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1390) CS PF04969.11 AIO00307.1 - 2.1e-15 57.0 0.0 2.9e-15 56.5 0.0 1.2 1 0 0 1 1 1 1 CS domain TPR_11 PF13414.1 AIO00309.1 - 6.9e-27 92.8 18.0 1.7e-10 40.3 0.7 6.2 5 1 1 6 6 6 4 TPR repeat TPR_2 PF07719.12 AIO00309.1 - 5.1e-25 85.3 17.9 0.00057 19.6 0.3 9.1 9 0 0 9 9 9 6 Tetratricopeptide repeat TPR_1 PF00515.23 AIO00309.1 - 2.8e-22 77.3 17.3 2.8e-05 23.5 0.3 7.8 8 0 0 8 8 8 6 Tetratricopeptide repeat TPR_16 PF13432.1 AIO00309.1 - 2e-18 66.5 7.3 0.0026 18.3 0.0 6.2 6 1 1 7 7 7 4 Tetratricopeptide repeat TPR_19 PF14559.1 AIO00309.1 - 2.3e-17 63.0 1.1 0.00039 20.6 0.1 6.2 5 2 2 7 7 7 3 Tetratricopeptide repeat TPR_12 PF13424.1 AIO00309.1 - 9.4e-17 60.7 14.2 4.7e-07 29.6 0.3 5.5 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_7 PF13176.1 AIO00309.1 - 1.5e-14 52.5 9.0 0.00046 19.7 0.1 7.2 7 1 0 7 7 7 4 Tetratricopeptide repeat TPR_8 PF13181.1 AIO00309.1 - 6.9e-12 44.2 14.3 0.0023 17.5 0.4 6.0 5 1 1 6 6 5 4 Tetratricopeptide repeat TPR_14 PF13428.1 AIO00309.1 - 2.2e-11 43.2 5.7 0.14 12.8 0.0 8.1 8 2 2 10 10 9 2 Tetratricopeptide repeat Apc3 PF12895.2 AIO00309.1 - 1.2e-10 41.3 22.3 0.001 19.1 0.9 4.8 4 2 1 5 5 4 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_15 PF13429.1 AIO00309.1 - 7.9e-07 28.4 0.4 0.031 13.3 0.0 4.1 2 1 3 5 5 5 1 Tetratricopeptide repeat TPR_6 PF13174.1 AIO00309.1 - 1.6e-06 28.1 11.1 0.0011 19.2 0.6 6.1 6 0 0 6 6 5 1 Tetratricopeptide repeat TPR_17 PF13431.1 AIO00309.1 - 5.6e-06 26.1 11.5 0.093 12.9 0.0 7.7 11 1 1 12 12 8 1 Tetratricopeptide repeat TPR_9 PF13371.1 AIO00309.1 - 8.1e-05 22.4 2.4 0.34 10.8 0.0 4.4 3 1 0 3 3 3 1 Tetratricopeptide repeat SNAP PF14938.1 AIO00309.1 - 0.018 14.2 7.8 0.019 14.1 1.6 2.9 2 1 0 2 2 2 0 Soluble NSF attachment protein, SNAP TPR_10 PF13374.1 AIO00309.1 - 0.02 14.8 12.7 0.097 12.6 0.2 5.4 5 0 0 5 5 5 0 Tetratricopeptide repeat NARP1 PF12569.3 AIO00309.1 - 0.043 12.5 0.2 0.12 11.1 0.1 1.8 2 1 0 2 2 2 0 NMDA receptor-regulated protein 1 Alkyl_sulf_dimr PF14863.1 AIO00309.1 - 0.075 13.2 0.0 44 4.2 0.0 3.3 2 1 0 3 3 3 0 Alkyl sulfatase dimerisation DUF3856 PF12968.2 AIO00309.1 - 0.086 12.6 1.1 0.36 10.6 0.2 2.5 2 0 0 2 2 2 0 Domain of Unknown Function (DUF3856) BTAD PF03704.12 AIO00309.1 - 0.27 11.5 9.5 2 8.6 0.0 4.6 4 2 1 5 5 5 0 Bacterial transcriptional activator domain Fis1_TPR_C PF14853.1 AIO00309.1 - 1 9.3 17.0 5.8 6.8 0.1 5.2 6 0 0 6 6 4 0 Fis1 C-terminal tetratricopeptide repeat Sel1 PF08238.7 AIO00309.1 - 1.7 9.3 15.0 19 6.0 0.1 6.0 7 0 0 7 7 6 0 Sel1 repeat GrpE PF01025.14 AIO00311.1 - 1.5e-40 138.4 3.5 1.8e-40 138.1 2.4 1.1 1 0 0 1 1 1 1 GrpE APG6 PF04111.7 AIO00311.1 - 0.13 11.3 0.6 0.16 10.9 0.4 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 GrpE PF01025.14 AIO00312.1 - 9.6e-36 122.8 2.8 1.2e-35 122.4 1.9 1.1 1 0 0 1 1 1 1 GrpE DUF964 PF06133.6 AIO00312.1 - 0.012 15.6 2.9 0.02 14.8 2.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF964) Spore_III_AB PF09548.5 AIO00312.1 - 0.013 15.2 0.5 0.021 14.5 0.3 1.3 1 0 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) Rootletin PF15035.1 AIO00312.1 - 0.046 13.6 5.3 0.087 12.7 3.7 1.4 1 1 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion WXG100 PF06013.7 AIO00312.1 - 0.064 13.2 2.0 0.091 12.7 1.4 1.2 1 0 0 1 1 1 0 Proteins of 100 residues with WXG TSC22 PF01166.13 AIO00312.1 - 0.17 11.9 4.4 0.28 11.1 1.5 2.1 2 0 0 2 2 2 0 TSC-22/dip/bun family DUF972 PF06156.8 AIO00312.1 - 0.18 12.1 4.4 0.52 10.6 1.8 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF972) Nup54 PF13874.1 AIO00312.1 - 0.72 9.5 5.3 2.8 7.5 0.4 2.2 1 1 1 2 2 2 0 Nucleoporin complex subunit 54 SlyX PF04102.7 AIO00312.1 - 6.6 7.1 6.5 13 6.2 0.3 2.5 1 1 1 2 2 2 0 SlyX DJ-1_PfpI PF01965.19 AIO00315.1 - 1.2e-24 86.4 0.0 1.5e-24 86.1 0.0 1.1 1 0 0 1 1 1 1 DJ-1/PfpI family DUF4066 PF13278.1 AIO00315.1 - 6e-08 32.1 0.0 7.2e-08 31.8 0.0 1.1 1 0 0 1 1 1 1 Putative amidotransferase Arm PF00514.18 AIO00316.1 - 2.3e-20 71.6 22.8 0.11 12.3 0.0 12.3 13 0 0 13 13 13 6 Armadillo/beta-catenin-like repeat Atx10homo_assoc PF09759.4 AIO00316.1 - 7.2e-12 44.9 14.2 0.15 11.8 0.0 8.2 4 3 3 8 8 8 5 Spinocerebellar ataxia type 10 protein domain HEAT_2 PF13646.1 AIO00316.1 - 1.6e-11 44.3 8.9 0.0032 17.7 0.2 6.5 3 1 4 7 7 7 4 HEAT repeats HEAT_EZ PF13513.1 AIO00316.1 - 4e-05 23.9 13.3 0.25 11.9 0.3 6.6 6 2 1 7 7 7 2 HEAT-like repeat Drf_GBD PF06371.8 AIO00316.1 - 0.028 13.7 0.3 2.7 7.2 0.1 2.7 2 0 0 2 2 2 0 Diaphanous GTPase-binding Domain V-ATPase_H_N PF03224.9 AIO00316.1 - 0.041 13.0 4.2 2.1 7.4 0.0 3.3 3 1 0 3 3 3 0 V-ATPase subunit H DUF1759 PF03564.10 AIO00316.1 - 0.11 12.3 1.4 0.83 9.4 0.1 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF1759) DOG1 PF14144.1 AIO00316.1 - 0.33 11.0 5.2 24 5.0 0.0 4.7 6 0 0 6 6 6 0 Seed dormancy control RIIa PF02197.12 AIO00317.1 - 0.024 14.0 0.2 0.062 12.7 0.0 1.8 2 0 0 2 2 2 0 Regulatory subunit of type II PKA R-subunit Pkinase PF00069.20 AIO00320.1 - 1.2e-70 237.6 0.0 2e-70 236.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AIO00320.1 - 2.7e-32 111.8 0.0 5e-32 110.9 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 AIO00320.1 - 7.7e-05 21.7 0.0 0.00024 20.1 0.0 1.8 2 0 0 2 2 2 1 Kinase-like PH PF00169.24 AIO00320.1 - 0.00013 22.1 0.0 0.00032 20.8 0.0 1.6 1 0 0 1 1 1 1 PH domain Kdo PF06293.9 AIO00320.1 - 0.0054 15.8 0.0 0.012 14.6 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 AIO00320.1 - 0.023 14.4 0.0 0.042 13.5 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Methyltransf_PK PF05891.7 AIO00321.1 - 2.1e-66 223.3 0.0 2.5e-66 223.1 0.0 1.0 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase Methyltransf_11 PF08241.7 AIO00321.1 - 2.6e-11 43.8 0.0 4.1e-11 43.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 AIO00321.1 - 3.6e-07 30.4 0.0 6.5e-07 29.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 AIO00321.1 - 1.6e-06 27.7 0.0 3.7e-06 26.6 0.0 1.5 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 AIO00321.1 - 2.6e-06 27.2 0.0 4.1e-06 26.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 AIO00321.1 - 4.6e-06 27.0 0.0 8e-06 26.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 AIO00321.1 - 1.9e-05 25.1 0.0 3.3e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 AIO00321.1 - 9.8e-05 21.7 0.0 0.00016 21.1 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_2 PF00891.13 AIO00321.1 - 0.0001 21.5 0.0 0.00012 21.3 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_26 PF13659.1 AIO00321.1 - 0.0084 16.1 0.0 0.015 15.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain DUF4105 PF13387.1 AIO00321.1 - 0.073 12.2 0.0 0.11 11.7 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4105) DUF2255 PF10012.4 AIO00321.1 - 0.077 12.9 0.0 0.13 12.2 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2255) Prefoldin_2 PF01920.15 AIO00323.1 - 1.7e-06 27.7 2.3 1.7e-06 27.7 1.6 1.7 1 1 0 1 1 1 1 Prefoldin subunit Med30 PF11315.3 AIO00323.1 - 0.0012 18.9 0.3 0.0012 18.9 0.2 2.0 1 1 1 2 2 2 1 Mediator complex subunit 30 YkyA PF10368.4 AIO00323.1 - 0.46 9.7 6.0 0.84 8.9 1.1 2.0 2 0 0 2 2 2 0 Putative cell-wall binding lipoprotein Sec2p PF06428.6 AIO00323.1 - 2.4 8.0 10.7 0.69 9.7 0.4 2.2 2 0 0 2 2 2 0 GDP/GTP exchange factor Sec2p OmpH PF03938.9 AIO00323.1 - 4 7.3 9.0 10 6.0 6.3 1.6 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF745 PF05335.8 AIO00323.1 - 4.2 6.8 10.5 0.33 10.4 1.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF745) MMR_HSR1 PF01926.18 AIO00324.1 - 5e-08 32.8 0.0 7.2e-07 29.1 0.0 2.5 2 1 0 2 2 2 1 50S ribosome-binding GTPase ATP_bind_1 PF03029.12 AIO00324.1 - 4e-06 26.5 0.0 0.00032 20.3 0.0 2.9 3 0 0 3 3 3 1 Conserved hypothetical ATP binding protein Dynamin_N PF00350.18 AIO00324.1 - 2.2e-05 24.3 0.0 0.00036 20.3 0.0 2.4 2 1 0 2 2 2 1 Dynamin family GTP_EFTU PF00009.22 AIO00324.1 - 0.00011 21.7 0.0 0.00024 20.6 0.0 1.5 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.13 AIO00324.1 - 0.00051 19.3 0.1 0.24 10.6 0.0 2.7 2 0 0 2 2 2 2 Ferrous iron transport protein B DUF258 PF03193.11 AIO00324.1 - 0.0083 15.3 0.0 0.035 13.2 0.0 2.0 1 1 0 1 1 1 1 Protein of unknown function, DUF258 Amastin PF07344.6 AIO00325.1 - 2.4e-42 144.1 9.3 2.9e-42 143.9 6.5 1.1 1 0 0 1 1 1 1 Amastin surface glycoprotein DUF4282 PF14110.1 AIO00325.1 - 0.24 11.5 8.7 0.75 10.0 6.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4282) DUF2628 PF10947.3 AIO00325.1 - 1.4 8.7 4.4 2.5 7.9 3.1 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2628) Amastin PF07344.6 AIO00326.1 - 7.5e-39 132.8 4.4 9.1e-39 132.5 3.0 1.1 1 0 0 1 1 1 1 Amastin surface glycoprotein Claudin_2 PF13903.1 AIO00326.1 - 0.004 16.8 5.7 0.004 16.8 4.0 2.0 1 1 1 2 2 2 1 PMP-22/EMP/MP20/Claudin tight junction Yip1 PF04893.12 AIO00326.1 - 0.0092 15.4 6.5 0.019 14.4 3.2 2.0 2 0 0 2 2 2 1 Yip1 domain zf-LITAF-like PF10601.4 AIO00326.1 - 0.14 12.0 2.7 1.5 8.7 0.0 2.9 2 1 1 3 3 3 0 LITAF-like zinc ribbon domain PfkB PF00294.19 AIO00327.1 - 9.6e-54 182.5 0.5 1.2e-53 182.2 0.4 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase DAGK_cat PF00781.19 AIO00327.1 - 0.012 15.0 0.0 0.024 14.0 0.0 1.4 1 0 0 1 1 1 0 Diacylglycerol kinase catalytic domain ThiG PF05690.9 AIO00327.1 - 0.09 11.8 0.1 0.4 9.7 0.0 1.9 2 0 0 2 2 2 0 Thiazole biosynthesis protein ThiG HECT PF00632.20 AIO00329.1 - 3.8e-74 249.6 0.0 5.3e-74 249.2 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Sua5_yciO_yrdC PF01300.13 AIO00329.1 - 0.15 11.3 0.0 0.31 10.2 0.0 1.4 1 0 0 1 1 1 0 Telomere recombination DUF2164 PF09932.4 AIO00330.1 - 0.058 13.2 0.0 0.18 11.6 0.0 1.8 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2164) DUF4139 PF13598.1 AIO00331.1 - 1.4e-89 300.5 0.4 2.1e-89 299.9 0.3 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4139) DUF4140 PF13600.1 AIO00331.1 - 2.5e-07 31.0 2.3 7e-05 23.2 0.3 2.7 2 0 0 2 2 2 2 N-terminal domain of unknown function (DUF4140) IncA PF04156.9 AIO00331.1 - 0.0092 15.5 0.6 1.4 8.4 0.0 2.3 2 0 0 2 2 2 2 IncA protein ADIP PF11559.3 AIO00331.1 - 0.19 11.6 1.2 13 5.6 0.1 2.2 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding Spc97_Spc98 PF04130.8 AIO00332.1 - 1.8e-23 82.6 0.0 1.1e-12 47.0 0.1 2.3 2 0 0 2 2 2 2 Spc97 / Spc98 family RWP-RK PF02042.10 AIO00332.1 - 0.053 13.3 0.4 0.14 12.0 0.0 1.8 2 0 0 2 2 2 0 RWP-RK domain DUF4214 PF13946.1 AIO00332.1 - 0.072 12.7 0.0 0.16 11.6 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4214) WD40 PF00400.27 AIO00333.1 - 5.5e-23 79.9 10.9 2.3e-08 33.6 0.4 5.8 6 0 0 6 6 6 5 WD domain, G-beta repeat CAF1C_H4-bd PF12265.3 AIO00333.1 - 2.7e-13 49.5 0.0 7.6e-13 48.1 0.0 1.8 1 0 0 1 1 1 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex MAM33 PF02330.11 AIO00335.1 - 4.3e-20 72.3 0.4 5.6e-18 65.4 0.8 2.0 1 1 1 2 2 2 2 Mitochondrial glycoprotein ABM PF03992.11 AIO00335.1 - 0.012 15.5 0.1 0.2 11.7 0.0 2.4 2 0 0 2 2 2 0 Antibiotic biosynthesis monooxygenase NUDIX_4 PF14815.1 AIO00336.1 - 0.11 11.9 0.3 0.28 10.6 0.1 1.7 2 0 0 2 2 2 0 NUDIX domain Pkinase PF00069.20 AIO00338.1 - 2.8e-37 128.3 0.0 1.4e-14 53.9 0.0 3.1 3 0 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.12 AIO00338.1 - 1.8e-22 79.6 0.0 1.3e-13 50.6 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 AIO00338.1 - 0.01 14.8 0.0 0.091 11.7 0.0 2.0 2 0 0 2 2 2 0 Kinase-like Med3 PF11593.3 AIO00338.1 - 0.3 10.2 0.0 0.3 10.2 0.0 2.5 3 0 0 3 3 3 0 Mediator complex subunit 3 fungal Ufd2P_core PF10408.4 AIO00339.1 - 3.5e-131 438.5 0.0 4.3e-131 438.2 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin elongating factor core Thioredoxin PF00085.15 AIO00339.1 - 2.5e-23 81.7 0.0 5.1e-23 80.7 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.1 AIO00339.1 - 5.5e-06 26.4 0.1 0.0028 17.7 0.1 2.7 1 1 1 2 2 2 2 Thioredoxin-like Thioredoxin_2 PF13098.1 AIO00339.1 - 9.3e-06 25.8 0.2 3.3e-05 24.0 0.1 1.9 1 0 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_7 PF13899.1 AIO00339.1 - 5.1e-05 23.2 0.1 0.00014 21.7 0.1 1.8 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_9 PF14595.1 AIO00339.1 - 0.0011 18.5 0.0 0.0033 16.9 0.0 1.8 1 0 0 1 1 1 1 Thioredoxin U-box PF04564.10 AIO00339.1 - 0.009 15.9 0.0 0.053 13.4 0.0 2.4 1 0 0 1 1 1 1 U-box domain AhpC-TSA PF00578.16 AIO00339.1 - 0.022 14.4 0.2 0.066 12.8 0.1 1.8 1 1 1 2 2 2 0 AhpC/TSA family Redoxin PF08534.5 AIO00339.1 - 0.04 13.4 0.2 0.67 9.4 0.1 2.2 1 1 1 2 2 2 0 Redoxin YlbD_coat PF14071.1 AIO00339.1 - 0.79 9.7 4.5 15 5.6 0.2 3.1 2 0 0 2 2 2 0 Putative coat protein DnaJ PF00226.26 AIO00341.1 - 0.0036 17.0 0.0 0.0083 15.8 0.0 1.7 1 0 0 1 1 1 1 DnaJ domain CytochromB561_N PF09786.4 AIO00341.1 - 0.072 11.5 0.9 0.088 11.2 0.6 1.2 1 0 0 1 1 1 0 Cytochrome B561, N terminal Herpes_capsid PF06112.6 AIO00341.1 - 0.56 10.2 15.3 0.17 11.8 5.7 2.8 3 0 0 3 3 3 0 Gammaherpesvirus capsid protein Mito_carr PF00153.22 AIO00343.1 - 1e-48 162.9 2.5 3.3e-18 65.1 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein RF-1 PF00472.15 AIO00344.1 - 6.6e-16 58.1 0.0 9.7e-16 57.5 0.0 1.3 1 0 0 1 1 1 1 RF-1 domain MRP-S28 PF10213.4 AIO00344.1 - 0.0025 17.8 0.0 0.0034 17.4 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial ribosomal subunit protein TRF PF08558.5 AIO00344.1 - 0.12 11.6 0.0 0.18 11.1 0.0 1.1 1 0 0 1 1 1 0 Telomere repeat binding factor (TRF) Sdh5 PF03937.11 AIO00345.1 - 3.3e-19 68.3 0.7 6.1e-19 67.4 0.5 1.4 1 0 0 1 1 1 1 Flavinator of succinate dehydrogenase WW PF00397.21 AIO00346.1 - 8.9e-11 41.4 3.8 1.7e-10 40.5 2.6 1.5 1 0 0 1 1 1 1 WW domain DivIVA PF05103.8 AIO00346.1 - 0.061 13.3 4.7 3.6 7.6 0.0 2.5 2 0 0 2 2 2 0 DivIVA protein DREV PF05219.7 AIO00347.1 - 6.1e-63 212.1 0.0 7.2e-63 211.9 0.0 1.0 1 0 0 1 1 1 1 DREV methyltransferase Methyltransf_23 PF13489.1 AIO00347.1 - 4.1e-13 49.3 0.0 6.1e-13 48.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 AIO00347.1 - 3e-12 46.8 0.0 5.1e-12 46.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 AIO00347.1 - 2.3e-10 40.8 0.0 4e-10 40.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 AIO00347.1 - 1.7e-07 31.8 0.0 3.1e-07 30.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 AIO00347.1 - 3.1e-06 26.8 0.0 1e-05 25.1 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 AIO00347.1 - 0.0045 17.3 0.0 0.016 15.5 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain CheR PF01739.13 AIO00347.1 - 0.011 14.9 0.0 0.017 14.3 0.0 1.2 1 0 0 1 1 1 0 CheR methyltransferase, SAM binding domain Methyltransf_26 PF13659.1 AIO00347.1 - 0.067 13.2 0.0 0.15 12.0 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain RrnaAD PF00398.15 AIO00347.1 - 0.083 11.9 0.0 0.11 11.4 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase RRM_1 PF00076.17 AIO00348.1 - 3.1e-21 74.7 0.0 1.6e-09 37.2 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 AIO00348.1 - 7.2e-15 54.7 0.0 1.5e-05 24.8 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 AIO00348.1 - 6.2e-12 45.1 0.0 0.0038 17.0 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RNA_bind PF08675.6 AIO00348.1 - 0.0098 15.8 0.0 0.5 10.3 0.0 2.6 3 0 0 3 3 3 1 RNA binding domain Nup35_RRM_2 PF14605.1 AIO00348.1 - 0.02 14.6 0.1 6 6.7 0.0 2.4 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif HpaP PF09483.5 AIO00348.1 - 0.03 14.2 3.4 0.051 13.5 2.4 1.3 1 0 0 1 1 1 0 Type III secretion protein (HpaP) Arm PF00514.18 AIO00349.1 - 2.5e-67 220.6 21.2 4.7e-10 38.9 0.0 9.1 10 0 0 10 10 10 8 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 AIO00349.1 - 6e-19 68.1 3.3 1e-05 25.7 0.3 5.6 1 1 3 5 5 5 5 HEAT repeats HEAT_EZ PF13513.1 AIO00349.1 - 8.5e-16 57.9 8.4 0.00049 20.4 0.1 6.5 6 1 1 7 7 7 4 HEAT-like repeat HEAT PF02985.17 AIO00349.1 - 9e-11 40.9 11.3 0.051 13.6 0.0 8.2 9 0 0 9 9 9 3 HEAT repeat Arm_2 PF04826.8 AIO00349.1 - 0.00014 21.0 0.0 0.018 14.1 0.0 3.6 3 1 1 4 4 4 1 Armadillo-like Proteasom_PSMB PF10508.4 AIO00349.1 - 0.0017 16.7 0.0 0.0029 15.9 0.0 1.3 1 0 0 1 1 1 1 Proteasome non-ATPase 26S subunit MA3 PF02847.12 AIO00352.1 - 7.2e-07 28.9 0.1 1.8e-06 27.6 0.0 1.6 1 0 0 1 1 1 1 MA3 domain DNA_pol3_gamma3 PF12169.3 AIO00352.1 - 0.018 14.7 2.8 0.21 11.3 0.0 3.6 4 0 0 4 4 4 0 DNA polymerase III subunits gamma and tau domain III zf-DHHC PF01529.15 AIO00354.1 - 1.9e-40 138.1 0.7 3e-40 137.4 0.5 1.3 1 0 0 1 1 1 1 DHHC palmitoyltransferase UCH PF00443.24 AIO00355.1 - 2.4e-41 141.6 0.0 4.1e-41 140.8 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 AIO00355.1 - 5.9e-08 32.4 0.4 0.0089 15.4 0.0 2.4 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase DUF859 PF05895.7 AIO00355.1 - 0.13 10.5 0.0 0.18 9.9 0.0 1.1 1 0 0 1 1 1 0 Siphovirus protein of unknown function (DUF859) LSM PF01423.17 AIO00356.1 - 1.3e-15 56.6 0.1 1.6e-15 56.4 0.1 1.1 1 0 0 1 1 1 1 LSM domain AAA_28 PF13521.1 AIO00357.1 - 2.3e-19 69.9 0.0 4.2e-19 69.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain ArgK PF03308.11 AIO00357.1 - 0.01 14.6 0.1 0.018 13.8 0.0 1.3 1 0 0 1 1 1 0 ArgK protein AAA_17 PF13207.1 AIO00357.1 - 0.016 16.0 0.0 0.038 14.8 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_29 PF13555.1 AIO00357.1 - 0.032 13.7 0.0 0.082 12.4 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain DAP3 PF10236.4 AIO00357.1 - 0.095 11.6 0.0 0.17 10.7 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 zf-C3HC4_3 PF13920.1 AIO00358.1 - 1.6e-07 30.8 13.5 1.6e-07 30.8 9.3 3.8 2 1 2 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 AIO00358.1 - 0.00019 21.3 16.3 0.00019 21.3 11.3 3.3 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) EF-hand_7 PF13499.1 AIO00359.1 - 0.00061 19.8 0.2 0.002 18.2 0.1 2.0 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.1 AIO00359.1 - 0.0061 16.3 0.1 0.021 14.6 0.0 1.9 1 0 0 1 1 1 1 EF-hand domain EF-hand_5 PF13202.1 AIO00359.1 - 0.013 14.7 0.1 0.028 13.7 0.1 1.6 1 0 0 1 1 1 0 EF hand EF-hand_1 PF00036.27 AIO00359.1 - 0.029 13.6 0.1 0.15 11.4 0.0 2.3 3 0 0 3 3 3 0 EF hand Phos_pyr_kin PF08543.7 AIO00360.1 - 3.2e-17 62.5 0.0 4.6e-17 62.0 0.0 1.2 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase PfkB PF00294.19 AIO00360.1 - 2e-10 40.2 2.8 5.5e-08 32.2 0.8 2.7 2 1 0 2 2 2 2 pfkB family carbohydrate kinase Acetyltransf_1 PF00583.19 AIO00361.1 - 1.6e-05 24.8 0.4 0.00022 21.2 0.0 2.6 2 1 1 3 3 3 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 AIO00361.1 - 0.00017 21.6 0.0 0.0011 19.1 0.0 2.0 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 AIO00361.1 - 0.00041 20.2 0.0 0.0025 17.6 0.0 2.0 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 AIO00361.1 - 0.0025 17.5 0.1 0.034 13.8 0.0 2.2 2 0 0 2 2 2 1 FR47-like protein Gla PF00594.15 AIO00361.1 - 0.084 12.5 0.4 0.15 11.7 0.3 1.4 1 0 0 1 1 1 0 Vitamin K-dependent carboxylation/gamma-carboxyglutamic (GLA) domain CENP-F_leu_zip PF10473.4 AIO00363.1 - 0.0039 17.0 0.4 0.0039 17.0 0.3 3.0 2 1 0 2 2 2 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Reo_sigmaC PF04582.7 AIO00363.1 - 0.035 13.2 8.1 0.35 10.0 1.1 2.5 1 1 0 2 2 2 0 Reovirus sigma C capsid protein AAA_23 PF13476.1 AIO00363.1 - 0.064 13.5 3.5 0.44 10.8 2.7 1.9 1 1 0 1 1 1 0 AAA domain DUF802 PF05650.6 AIO00363.1 - 1.1 9.3 21.2 0.68 10.0 3.6 4.6 2 1 0 2 2 2 0 Domain of unknown function (DUF802) Atg14 PF10186.4 AIO00363.1 - 1.2 8.0 15.4 3.5 6.4 5.9 2.9 2 0 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 Seryl_tRNA_N PF02403.17 AIO00363.1 - 9.8 6.2 19.4 0.19 11.7 0.1 3.5 4 1 0 4 4 4 0 Seryl-tRNA synthetase N-terminal domain Clathrin PF00637.15 AIO00364.1 - 2.1e-09 37.0 0.1 2.9e-08 33.4 0.3 2.2 2 0 0 2 2 2 1 Region in Clathrin and VPS zf-RING_2 PF13639.1 AIO00364.1 - 0.0011 18.7 5.2 0.0039 16.9 3.6 2.0 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 AIO00364.1 - 0.014 15.3 4.7 0.045 13.7 3.3 1.9 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 AIO00364.1 - 0.025 14.6 1.6 0.072 13.2 1.1 1.7 1 0 0 1 1 1 0 RING-H2 zinc finger zf-Apc11 PF12861.2 AIO00364.1 - 0.044 13.6 0.9 0.16 11.7 0.6 2.0 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger LysM PF01476.15 AIO00364.1 - 0.077 12.9 0.0 0.18 11.7 0.0 1.6 1 0 0 1 1 1 0 LysM domain zf-RING_6 PF14835.1 AIO00364.1 - 0.086 12.6 1.0 0.26 11.1 0.7 1.8 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-C3HC4 PF00097.20 AIO00364.1 - 0.11 12.1 4.0 0.28 10.8 2.8 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 AIO00364.1 - 2.2 8.0 7.8 0.48 10.1 2.4 2.2 2 0 0 2 2 2 0 zinc-RING finger domain Brix PF04427.13 AIO00365.1 - 4.4e-43 147.1 0.2 5.7e-43 146.8 0.2 1.1 1 0 0 1 1 1 1 Brix domain SNF2_N PF00176.18 AIO00366.1 - 9.1e-50 169.1 0.0 1.3e-49 168.5 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 AIO00366.1 - 1.1e-06 28.4 0.0 2.4e-06 27.3 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 AIO00366.1 - 0.012 15.4 0.0 1.6 8.5 0.0 2.3 1 1 1 2 2 2 0 Type III restriction enzyme, res subunit ABC_tran PF00005.22 AIO00368.1 - 8.7e-19 68.1 1.1 5.3e-13 49.4 0.5 3.1 2 1 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 AIO00368.1 - 4.1e-10 40.1 0.5 4.7e-05 23.5 0.0 2.4 2 0 0 2 2 2 2 AAA domain SMC_N PF02463.14 AIO00368.1 - 2.7e-05 23.5 1.2 0.2 10.8 0.0 3.1 3 0 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 AIO00368.1 - 0.00026 20.4 0.0 0.00054 19.4 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain DUF258 PF03193.11 AIO00368.1 - 0.0031 16.7 0.0 0.0052 15.9 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_15 PF13175.1 AIO00368.1 - 0.0052 15.8 0.0 1.2 8.0 0.0 2.1 2 0 0 2 2 2 2 AAA ATPase domain AAA_23 PF13476.1 AIO00368.1 - 0.0097 16.2 0.0 0.092 13.0 0.0 2.0 2 0 0 2 2 2 1 AAA domain FtsK_SpoIIIE PF01580.13 AIO00368.1 - 0.011 15.1 0.1 0.026 13.9 0.0 1.6 2 0 0 2 2 2 0 FtsK/SpoIIIE family Dynamin_N PF00350.18 AIO00368.1 - 0.033 14.0 0.1 0.062 13.1 0.1 1.4 1 0 0 1 1 1 0 Dynamin family AAA_10 PF12846.2 AIO00368.1 - 0.093 12.1 0.4 0.28 10.5 0.1 1.9 3 0 0 3 3 3 0 AAA-like domain AAA_16 PF13191.1 AIO00368.1 - 0.1 12.5 0.7 0.35 10.8 0.3 2.1 2 1 0 2 2 2 0 AAA ATPase domain AAA_33 PF13671.1 AIO00368.1 - 0.12 12.3 0.1 0.34 10.7 0.1 1.7 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.1 AIO00368.1 - 0.12 12.3 0.5 0.36 10.7 0.0 2.0 2 0 0 2 2 2 0 AAA domain Miro PF08477.8 AIO00368.1 - 0.17 12.4 0.1 0.33 11.4 0.0 1.5 1 0 0 1 1 1 0 Miro-like protein AAA_17 PF13207.1 AIO00368.1 - 0.19 12.5 0.5 0.64 10.8 0.4 2.2 1 1 0 1 1 1 0 AAA domain G-alpha PF00503.15 AIO00368.1 - 0.21 10.2 0.0 0.32 9.6 0.0 1.1 1 0 0 1 1 1 0 G-protein alpha subunit RabGAP-TBC PF00566.13 AIO00370.1 - 1.8e-34 119.1 0.3 3.3e-34 118.2 0.2 1.4 1 0 0 1 1 1 1 Rab-GTPase-TBC domain RIO1 PF01163.17 AIO00371.1 - 4.6e-45 153.2 0.0 9.8e-45 152.2 0.0 1.5 1 0 0 1 1 1 1 RIO1 family Rio2_N PF09202.6 AIO00371.1 - 3.3e-32 110.3 0.4 7.6e-31 106.0 0.2 2.3 2 0 0 2 2 2 1 Rio2, N-terminal APH PF01636.18 AIO00371.1 - 8.6e-10 38.7 0.0 5.3e-05 23.0 0.0 2.4 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.9 AIO00371.1 - 0.00013 21.1 0.0 0.0032 16.5 0.0 2.8 2 1 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family PSP1 PF04468.7 AIO00372.1 - 2.6e-08 33.7 0.1 5.2e-08 32.7 0.1 1.5 1 0 0 1 1 1 1 PSP1 C-terminal conserved region PLAC8 PF04749.12 AIO00373.1 - 5.6e-20 71.8 12.3 8.6e-20 71.2 8.5 1.3 1 0 0 1 1 1 1 PLAC8 family DUF1360 PF07098.6 AIO00373.1 - 0.032 13.9 1.5 0.062 13.0 1.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1360) S_tail_recep_bd PF14928.1 AIO00373.1 - 0.16 12.1 0.0 0.24 11.6 0.0 1.3 1 0 0 1 1 1 0 Short tail fibre protein receptor-binding domain WD40 PF00400.27 AIO00374.1 - 1.3e-31 107.3 4.9 6.2e-06 25.8 0.2 7.7 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 AIO00374.1 - 0.0016 16.6 0.3 1.4 6.9 0.1 2.8 2 1 1 3 3 3 2 Nucleoporin Nup120/160 Kinesin PF00225.18 AIO00375.1 - 1.5e-83 280.2 0.3 1.5e-83 280.2 0.2 1.5 2 0 0 2 2 2 1 Kinesin motor domain Mcp5_PH PF12814.2 AIO00375.1 - 1.8e-05 24.6 0.0 7.3e-05 22.6 0.0 2.1 1 0 0 1 1 1 1 Meiotic cell cortex C-terminal pleckstrin homology S1-P1_nuclease PF02265.11 AIO00376.1 - 3.4e-58 197.2 0.0 4.1e-58 196.9 0.0 1.1 1 0 0 1 1 1 1 S1/P1 Nuclease PseudoU_synth_2 PF00849.17 AIO00377.1 - 1.4e-32 112.7 0.0 6e-32 110.7 0.0 1.9 1 1 0 1 1 1 1 RNA pseudouridylate synthase DUF2109 PF09882.4 AIO00377.1 - 0.01 15.7 0.0 0.07 13.0 0.0 2.1 2 0 0 2 2 2 0 Predicted membrane protein (DUF2109) Rad17 PF03215.10 AIO00378.1 - 2e-08 33.4 0.1 0.00042 19.1 0.0 3.1 2 1 1 3 3 3 2 Rad17 cell cycle checkpoint protein RuvB_N PF05496.7 AIO00378.1 - 0.018 14.1 0.0 0.05 12.6 0.0 1.7 2 0 0 2 2 2 0 Holliday junction DNA helicase ruvB N-terminus AAA PF00004.24 AIO00378.1 - 0.044 13.9 0.0 0.27 11.4 0.0 2.1 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Flavoprotein PF02441.14 AIO00379.1 - 3.4e-43 146.3 4.3 3.5e-43 146.3 0.6 2.2 2 0 0 2 2 2 1 Flavoprotein PseudoU_synth_1 PF01416.15 AIO00380.1 - 2.7e-26 92.0 0.0 3.7e-18 65.8 0.0 2.4 2 0 0 2 2 2 2 tRNA pseudouridine synthase Pkinase PF00069.20 AIO00381.1 - 2.2e-33 115.5 0.0 1.5e-12 47.2 0.1 3.4 3 0 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.12 AIO00381.1 - 2.1e-16 59.7 0.0 1.4e-06 27.5 0.0 3.2 3 0 0 3 3 3 2 Protein tyrosine kinase Kinase-like PF14531.1 AIO00381.1 - 0.048 12.6 0.1 0.1 11.5 0.1 1.5 1 0 0 1 1 1 0 Kinase-like DUF1796 PF08795.5 AIO00382.1 - 8e-66 220.7 0.0 1.6e-65 219.8 0.0 1.5 2 0 0 2 2 2 1 Putative papain-like cysteine peptidase (DUF1796) PH PF00169.24 AIO00383.1 - 7.5e-06 26.0 3.8 0.0052 16.9 0.4 2.8 2 1 0 2 2 2 2 PH domain Kelch_4 PF13418.1 AIO00383.1 - 4.4e-05 23.1 0.4 0.45 10.3 0.0 4.6 4 0 0 4 4 4 2 Galactose oxidase, central domain Kelch_1 PF01344.20 AIO00383.1 - 0.0012 18.3 0.6 0.21 11.1 0.1 4.0 4 0 0 4 4 4 1 Kelch motif Kelch_3 PF13415.1 AIO00383.1 - 0.0017 18.4 0.6 9.9 6.4 0.0 5.6 6 1 0 6 6 6 1 Galactose oxidase, central domain Kelch_5 PF13854.1 AIO00383.1 - 0.0073 16.2 0.9 14 5.7 0.0 4.0 4 0 0 4 4 4 1 Kelch motif PH_11 PF15413.1 AIO00383.1 - 0.48 10.6 3.7 2.8 8.2 0.1 2.8 3 0 0 3 3 3 0 Pleckstrin homology domain Actin PF00022.14 AIO00385.1 - 0.00074 18.0 0.0 0.0016 16.9 0.0 1.5 2 0 0 2 2 2 1 Actin NAD_binding_6 PF08030.7 AIO00386.1 - 4.1e-12 46.2 0.0 2e-06 27.7 0.0 2.7 2 1 0 2 2 2 2 Ferric reductase NAD binding domain Ferric_reduct PF01794.14 AIO00386.1 - 9.5e-12 45.0 12.4 9.5e-12 45.0 8.6 3.3 3 1 0 3 3 3 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.7 AIO00386.1 - 6.3e-10 38.8 0.0 1.6e-09 37.5 0.0 1.7 1 0 0 1 1 1 1 FAD-binding domain FAD_binding_6 PF00970.19 AIO00386.1 - 0.00038 20.5 0.0 0.00099 19.1 0.0 1.7 1 1 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.16 AIO00386.1 - 0.0038 17.7 0.0 0.76 10.3 0.0 2.7 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain Myc_target_1 PF15179.1 AIO00386.1 - 0.1 12.2 0.0 0.21 11.1 0.0 1.5 1 0 0 1 1 1 0 Myc target protein 1 DUF1077 PF06417.7 AIO00389.1 - 1.3e-42 144.1 1.1 1.5e-42 143.9 0.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1077) UbiA PF01040.13 AIO00389.1 - 0.034 13.3 0.3 0.05 12.8 0.2 1.3 1 1 0 1 1 1 0 UbiA prenyltransferase family DUF1352 PF07086.7 AIO00389.1 - 0.057 13.0 0.1 0.067 12.8 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1352) HSP33 PF01430.14 AIO00390.1 - 8.9e-08 31.5 1.1 0.00051 19.2 0.1 2.6 3 0 0 3 3 3 2 Hsp33 protein AAA_2 PF07724.9 AIO00392.1 - 5.1e-08 33.0 0.0 8.2e-08 32.3 0.0 1.3 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.1 AIO00392.1 - 1.1e-06 28.8 0.0 5e-06 26.6 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.9 AIO00392.1 - 3.4e-05 23.5 0.0 0.0001 22.0 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 AIO00392.1 - 0.0007 19.6 0.0 0.035 14.0 0.0 2.8 2 0 0 2 2 2 1 AAA ATPase domain AAA PF00004.24 AIO00392.1 - 0.0024 18.0 0.0 0.0053 16.9 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DUF2721 PF11026.3 AIO00392.1 - 0.0094 15.5 5.4 0.028 14.0 3.7 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF2721) NPR1_like_C PF12313.3 AIO00392.1 - 0.013 14.9 1.1 0.11 11.8 0.1 2.2 2 0 0 2 2 2 0 NPR1/NIM1 like defence protein C terminal AAA_17 PF13207.1 AIO00392.1 - 0.051 14.3 0.0 0.12 13.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.1 AIO00392.1 - 0.068 13.0 0.0 0.16 11.8 0.0 1.8 1 1 0 1 1 1 0 AAA domain Baculo_RING PF05883.6 AIO00392.1 - 0.21 11.4 0.1 0.38 10.5 0.0 1.3 1 0 0 1 1 1 0 Baculovirus U-box/Ring-like domain RNA_helicase PF00910.17 AIO00392.1 - 0.22 11.7 0.0 0.61 10.2 0.0 1.7 2 0 0 2 2 2 0 RNA helicase ABC2_membrane_3 PF12698.2 AIO00392.1 - 9.5 5.1 8.8 19 4.1 6.1 1.4 1 0 0 1 1 1 0 ABC-2 family transporter protein Ras PF00071.17 AIO00393.1 - 2.1e-39 134.4 0.0 2.6e-39 134.1 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 AIO00393.1 - 1.1e-16 61.4 0.0 1.6e-16 60.8 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 AIO00393.1 - 2.5e-12 46.3 0.0 3.4e-12 45.9 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 AIO00393.1 - 0.0005 19.2 0.0 0.00069 18.8 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region FeoB_N PF02421.13 AIO00393.1 - 0.00094 18.4 0.0 0.92 8.7 0.0 2.3 2 0 0 2 2 2 2 Ferrous iron transport protein B MMR_HSR1 PF01926.18 AIO00393.1 - 0.0023 17.8 0.0 0.0035 17.2 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase G-alpha PF00503.15 AIO00393.1 - 0.0044 15.7 0.0 0.44 9.1 0.0 2.3 1 1 1 2 2 2 2 G-protein alpha subunit GTP_EFTU PF00009.22 AIO00393.1 - 0.019 14.3 0.1 0.12 11.7 0.1 2.0 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain PduV-EutP PF10662.4 AIO00393.1 - 0.054 12.9 0.0 0.39 10.2 0.0 2.0 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation ATG16 PF08614.6 AIO00395.1 - 0.00015 21.6 16.2 0.011 15.6 1.5 2.2 2 0 0 2 2 2 2 Autophagy protein 16 (ATG16) APG6 PF04111.7 AIO00395.1 - 0.092 11.7 23.0 0.29 10.1 7.7 2.1 2 0 0 2 2 2 0 Autophagy protein Apg6 BBS2_C PF14782.1 AIO00395.1 - 0.63 8.5 16.0 0.062 11.8 4.3 2.0 2 0 0 2 2 2 0 Ciliary BBSome complex subunit 2, C-terminal DUF3496 PF12001.3 AIO00395.1 - 1.5 9.0 9.9 0.16 12.2 0.9 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3496) Mnd1 PF03962.10 AIO00395.1 - 3.6 7.2 21.6 4.8 6.8 2.3 2.2 2 0 0 2 2 2 0 Mnd1 family IncA PF04156.9 AIO00395.1 - 6.6 6.2 19.5 0.68 9.4 1.5 2.2 2 0 0 2 2 2 0 IncA protein FadA PF09403.5 AIO00395.1 - 9.3 6.2 19.0 6.1 6.8 3.9 2.3 2 0 0 2 2 2 0 Adhesion protein FadA PEX11 PF05648.9 AIO00397.1 - 0.079 12.2 0.0 0.1 11.8 0.0 1.2 1 0 0 1 1 1 0 Peroxisomal biogenesis factor 11 (PEX11) CLASP_N PF12348.3 AIO00398.1 - 2.2e-11 43.5 0.3 9e-07 28.4 0.0 4.2 4 0 0 4 4 4 2 CLASP N terminal HEAT PF02985.17 AIO00398.1 - 0.04 14.0 4.9 1.4 9.2 0.0 5.4 6 0 0 6 6 6 0 HEAT repeat IFT46_B_C PF12317.3 AIO00399.1 - 1.3e-92 309.0 0.5 1.5e-92 308.7 0.4 1.1 1 0 0 1 1 1 1 Intraflagellar transport complex B protein 46 C terminal Nucleoplasmin PF03066.10 AIO00399.1 - 0.28 10.6 2.7 0.41 10.1 1.9 1.3 1 0 0 1 1 1 0 Nucleoplasmin Pkinase PF00069.20 AIO00400.1 - 4.5e-31 107.9 0.0 1.2e-29 103.2 0.0 2.7 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 AIO00400.1 - 7.7e-08 31.7 0.0 2e-06 27.0 0.0 2.5 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 AIO00400.1 - 0.00052 19.8 0.0 0.0013 18.4 0.0 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.1 AIO00400.1 - 0.14 11.0 0.0 0.51 9.2 0.0 1.9 3 0 0 3 3 3 0 Kinase-like DnaJ PF00226.26 AIO00401.1 - 4.5e-20 71.1 0.2 1.7e-19 69.3 0.0 2.0 2 0 0 2 2 2 1 DnaJ domain SplA PF11132.3 AIO00401.1 - 0.12 12.1 0.7 2.3 8.0 0.0 2.5 2 0 0 2 2 2 0 Transcriptional regulator protein (SplA) TGT PF01702.13 AIO00402.1 - 1.4e-85 286.4 0.0 2.2e-85 285.7 0.0 1.3 1 0 0 1 1 1 1 Queuine tRNA-ribosyltransferase PapD-like PF14874.1 AIO00403.1 - 6.8e-19 67.7 32.6 0.00037 20.3 0.0 14.1 17 0 0 17 17 15 4 Flagellar-associated PapD-like Motile_Sperm PF00635.21 AIO00403.1 - 1.7e-11 43.6 9.2 6.8 6.3 0.0 13.2 16 0 0 16 16 15 1 MSP (Major sperm protein) domain MYCBPAP PF14646.1 AIO00403.1 - 2.7e-05 23.0 0.0 39 2.7 0.0 8.0 9 1 1 10 10 10 0 MYCBP-associated protein family Zeta_toxin PF06414.7 AIO00403.1 - 4.9e-05 22.5 0.0 0.00011 21.4 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin FixG_C PF11614.3 AIO00403.1 - 0.0016 18.5 0.5 21 5.2 0.0 6.4 6 0 0 6 6 6 0 IG-like fold at C-terminal of FixG, putative oxidoreductase PapD_N PF00345.15 AIO00403.1 - 0.0028 17.4 0.0 0.97 9.2 0.0 4.0 2 0 0 2 2 2 1 Pili and flagellar-assembly chaperone, PapD N-terminal domain AAA_33 PF13671.1 AIO00403.1 - 0.0032 17.3 0.0 0.01 15.7 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 AIO00403.1 - 0.0086 16.2 0.0 0.022 14.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA PF00004.24 AIO00403.1 - 0.18 12.0 0.0 0.37 10.9 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) BsuPI PF12690.2 AIO00403.1 - 0.2 11.3 0.0 1.5e+02 2.1 0.0 4.4 5 0 0 5 5 5 0 Intracellular proteinase inhibitor AAA_17 PF13207.1 AIO00403.1 - 0.26 12.1 0.0 0.61 10.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain KTI12 PF08433.5 AIO00403.1 - 0.51 9.5 0.0 1.1 8.4 0.0 1.4 1 0 0 1 1 1 0 Chromatin associated protein KTI12 Trigger_C PF05698.9 AIO00403.1 - 0.61 9.9 1.5 1.1 9.0 1.0 1.3 1 0 0 1 1 1 0 Bacterial trigger factor protein (TF) C-terminus AAA_14 PF13173.1 AIO00403.1 - 0.69 9.8 0.0 1.3 8.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain SRPRB PF09439.5 AIO00403.1 - 1.2 8.3 0.0 2.6 7.2 0.0 1.5 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit Njmu-R1 PF15053.1 AIO00403.1 - 3.7 6.1 0.0 6.8 5.3 0.0 1.3 1 0 0 1 1 1 0 Mjmu-R1-like protein family DUF3449 PF11931.3 AIO00404.1 - 1.5e-42 145.3 0.4 3.2e-42 144.2 0.0 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF3449) FYVE PF01363.16 AIO00406.1 - 2.3e-11 43.4 6.1 2.3e-11 43.4 4.2 2.3 2 0 0 2 2 2 1 FYVE zinc finger PI3_PI4_kinase PF00454.22 AIO00406.1 - 3.5e-09 36.4 0.6 5.1e-07 29.4 0.1 2.4 2 0 0 2 2 2 2 Phosphatidylinositol 3- and 4-kinase zf-ribbon_3 PF13248.1 AIO00406.1 - 0.014 14.5 0.7 0.051 12.7 0.5 2.0 1 0 0 1 1 1 0 zinc-ribbon domain OrfB_Zn_ribbon PF07282.6 AIO00406.1 - 1.5 8.5 8.1 0.19 11.3 2.1 2.2 2 0 0 2 2 2 0 Putative transposase DNA-binding domain zf-CHY PF05495.7 AIO00409.1 - 8.9 6.5 6.6 3 8.0 1.1 2.3 1 1 1 2 2 2 0 CHY zinc finger AAA_18 PF13238.1 AIO00410.1 - 3e-26 92.2 0.1 4.4e-26 91.6 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 AIO00410.1 - 2.7e-13 50.7 0.1 4.9e-13 49.9 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 AIO00410.1 - 2.3e-07 30.7 0.1 2.9e-05 23.9 0.1 2.3 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.1 AIO00410.1 - 1.3e-05 25.2 1.4 4.3e-05 23.5 0.8 2.1 1 1 0 1 1 1 1 AAA domain AAA PF00004.24 AIO00410.1 - 1.4e-05 25.3 0.4 2.3e-05 24.5 0.3 1.8 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) SKI PF01202.17 AIO00410.1 - 0.00013 21.8 4.8 0.0019 18.1 3.3 2.2 1 1 0 1 1 1 1 Shikimate kinase RuvB_N PF05496.7 AIO00410.1 - 0.00028 20.0 0.0 0.00041 19.4 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 AIO00410.1 - 0.0014 18.7 0.0 0.0036 17.4 0.0 1.6 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 AIO00410.1 - 0.0018 17.4 0.0 0.0035 16.4 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin RNA_helicase PF00910.17 AIO00410.1 - 0.0021 18.1 0.0 0.0044 17.1 0.0 1.5 1 0 0 1 1 1 1 RNA helicase DUF2075 PF09848.4 AIO00410.1 - 0.0029 16.6 0.1 0.0035 16.3 0.0 1.4 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_5 PF07728.9 AIO00410.1 - 0.0029 17.3 0.2 0.007 16.0 0.1 1.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_24 PF13479.1 AIO00410.1 - 0.0033 17.0 0.2 0.0082 15.7 0.1 1.6 1 0 0 1 1 1 1 AAA domain ADK PF00406.17 AIO00410.1 - 0.0036 17.1 0.4 0.26 11.1 0.0 2.2 2 0 0 2 2 2 1 Adenylate kinase AAA_16 PF13191.1 AIO00410.1 - 0.004 17.1 0.0 0.0081 16.1 0.0 1.5 2 0 0 2 2 1 1 AAA ATPase domain AAA_19 PF13245.1 AIO00410.1 - 0.0054 16.4 0.1 0.011 15.4 0.0 1.5 1 0 0 1 1 1 1 Part of AAA domain Mg_chelatase PF01078.16 AIO00410.1 - 0.0055 15.8 0.2 0.022 13.9 0.0 1.9 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI KaiC PF06745.8 AIO00410.1 - 0.0066 15.5 0.1 0.015 14.3 0.1 1.5 1 0 0 1 1 1 1 KaiC dNK PF01712.14 AIO00410.1 - 0.008 16.0 0.1 0.014 15.3 0.1 1.5 1 0 0 1 1 1 1 Deoxynucleoside kinase KTI12 PF08433.5 AIO00410.1 - 0.0093 15.1 0.1 0.027 13.6 0.0 1.7 2 0 0 2 2 2 1 Chromatin associated protein KTI12 TIP49 PF06068.8 AIO00410.1 - 0.0096 14.6 0.0 0.0096 14.6 0.0 1.2 1 0 0 1 1 1 1 TIP49 C-terminus IstB_IS21 PF01695.12 AIO00410.1 - 0.017 14.5 0.7 0.03 13.7 0.1 1.6 2 0 0 2 2 2 0 IstB-like ATP binding protein Cytidylate_kin2 PF13189.1 AIO00410.1 - 0.025 14.4 1.9 0.15 11.9 0.1 2.5 1 1 1 2 2 2 0 Cytidylate kinase-like family Parvo_NS1 PF01057.12 AIO00410.1 - 0.028 13.2 0.1 0.058 12.2 0.0 1.5 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 Sigma54_activat PF00158.21 AIO00410.1 - 0.037 13.4 0.2 0.087 12.2 0.0 1.6 2 0 0 2 2 1 0 Sigma-54 interaction domain NTPase_1 PF03266.10 AIO00410.1 - 0.04 13.6 1.8 0.069 12.8 0.1 2.2 1 1 2 3 3 3 0 NTPase AAA_14 PF13173.1 AIO00410.1 - 0.047 13.5 0.2 0.14 12.0 0.0 1.8 2 0 0 2 2 2 0 AAA domain Sars6 PF12133.3 AIO00410.1 - 0.049 13.3 0.0 0.11 12.2 0.0 1.6 1 0 0 1 1 1 0 Open reading frame 6 from SARS coronavirus CoaE PF01121.15 AIO00410.1 - 0.052 12.9 0.8 3.7 6.8 0.1 2.2 2 0 0 2 2 2 0 Dephospho-CoA kinase AAA_23 PF13476.1 AIO00410.1 - 0.052 13.8 1.0 0.1 12.9 0.7 1.6 1 1 0 1 1 1 0 AAA domain Torsin PF06309.6 AIO00410.1 - 0.053 13.4 0.0 0.11 12.4 0.0 1.5 1 0 0 1 1 1 0 Torsin AAA_3 PF07726.6 AIO00410.1 - 0.055 13.0 0.0 0.12 12.0 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ABC_tran PF00005.22 AIO00410.1 - 0.06 13.6 2.1 0.48 10.7 1.5 2.1 1 1 0 1 1 1 0 ABC transporter AAA_25 PF13481.1 AIO00410.1 - 0.069 12.5 0.1 0.17 11.2 0.0 1.8 2 1 0 2 2 2 0 AAA domain Thymidylate_kin PF02223.12 AIO00410.1 - 0.085 12.2 2.2 8.2 5.7 0.2 2.6 2 1 1 3 3 3 0 Thymidylate kinase KAP_NTPase PF07693.9 AIO00410.1 - 0.087 11.8 0.0 0.11 11.4 0.0 1.3 1 1 0 1 1 1 0 KAP family P-loop domain APS_kinase PF01583.15 AIO00410.1 - 0.09 12.4 0.0 0.21 11.2 0.0 1.7 2 0 0 2 2 2 0 Adenylylsulphate kinase FtsK_SpoIIIE PF01580.13 AIO00410.1 - 0.095 12.1 0.2 0.2 11.1 0.0 1.7 2 0 0 2 2 2 0 FtsK/SpoIIIE family TrwB_AAD_bind PF10412.4 AIO00410.1 - 0.098 11.2 0.3 0.17 10.4 0.2 1.3 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain CPT PF07931.7 AIO00410.1 - 0.13 11.8 2.6 1.3 8.5 0.0 2.7 2 1 1 3 3 3 0 Chloramphenicol phosphotransferase-like protein Miro PF08477.8 AIO00410.1 - 0.14 12.6 0.3 0.43 11.0 0.1 1.9 1 1 1 2 2 2 0 Miro-like protein MobB PF03205.9 AIO00410.1 - 0.18 11.4 0.6 0.43 10.2 0.0 1.9 2 2 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B UvrD-helicase PF00580.16 AIO00410.1 - 4.1 6.5 5.6 7.6 5.7 0.2 2.4 1 1 0 2 2 2 0 UvrD/REP helicase N-terminal domain Elf1 PF05129.8 AIO00412.1 - 0.099 12.3 3.3 0.2 11.3 2.3 1.5 1 0 0 1 1 1 0 Transcription elongation factor Elf1 like CoA_trans PF01144.18 AIO00413.1 - 3.3e-75 251.9 0.0 3e-48 163.8 0.0 2.1 2 0 0 2 2 2 2 Coenzyme A transferase PseudoU_synth_2 PF00849.17 AIO00415.1 - 3.6e-18 65.9 0.1 1.3e-08 34.8 0.0 2.6 2 0 0 2 2 2 2 RNA pseudouridylate synthase S4 PF01479.20 AIO00415.1 - 0.0018 17.6 0.0 0.0049 16.2 0.0 1.8 2 0 0 2 2 2 1 S4 domain TPR_MLP1_2 PF07926.7 AIO00416.1 - 0.022 14.5 16.9 0.9 9.2 0.3 3.3 3 0 0 3 3 3 0 TPR/MLP1/MLP2-like protein DUF1154 PF06631.6 AIO00416.1 - 0.52 10.0 3.7 4 7.1 2.5 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1154) Syntaxin-6_N PF09177.6 AIO00416.1 - 1.9 8.9 10.6 0.079 13.3 0.4 3.0 3 0 0 3 3 3 0 Syntaxin 6, N-terminal zf-C2H2_2 PF12756.2 AIO00418.1 - 9.7e-21 73.7 6.4 3.5e-14 52.7 0.3 2.3 2 0 0 2 2 2 2 C2H2 type zinc-finger (2 copies) zf-Di19 PF05605.7 AIO00418.1 - 5.2e-05 23.2 9.6 0.015 15.3 0.1 4.3 3 1 1 4 4 4 1 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_4 PF13894.1 AIO00418.1 - 0.00072 19.7 3.3 0.25 11.7 0.1 3.9 4 0 0 4 4 4 1 C2H2-type zinc finger Rad50_zn_hook PF04423.9 AIO00418.1 - 0.035 13.5 2.5 0.14 11.6 0.0 2.6 2 0 0 2 2 2 0 Rad50 zinc hook motif Clr5 PF14420.1 AIO00418.1 - 0.16 11.9 0.2 0.93 9.4 0.0 2.3 2 0 0 2 2 2 0 Clr5 domain zf-C2H2 PF00096.21 AIO00418.1 - 2.6 8.5 10.0 9.8 6.7 0.0 4.5 4 1 0 4 4 4 0 Zinc finger, C2H2 type PC_rep PF01851.17 AIO00419.1 - 0.087 13.0 11.7 13 6.2 0.0 6.1 6 0 0 6 6 6 0 Proteasome/cyclosome repeat IFT20 PF14931.1 AIO00420.1 - 2.1e-37 127.6 6.6 2.3e-37 127.5 4.6 1.0 1 0 0 1 1 1 1 Intraflagellar transport complex B, subunit 20 VQ PF05678.9 AIO00420.1 - 0.17 10.9 4.9 1.3 8.1 0.1 2.8 3 0 0 3 3 3 0 VQ motif Snapin_Pallidin PF14712.1 AIO00420.1 - 0.22 11.8 4.1 4.6 7.6 0.0 2.2 2 0 0 2 2 2 0 Snapin/Pallidin Mannosyl_trans PF05007.8 AIO00421.1 - 5e-83 278.7 13.2 7.1e-83 278.2 9.1 1.2 1 0 0 1 1 1 1 Mannosyltransferase (PIG-M) DUF2029 PF09594.5 AIO00421.1 - 6.2e-12 45.5 11.1 6.2e-12 45.5 7.7 2.6 1 1 0 2 2 2 1 Protein of unknown function (DUF2029) PIG-U PF06728.8 AIO00421.1 - 7.5e-11 41.5 16.2 1.4e-10 40.6 10.6 1.8 1 1 0 1 1 1 1 GPI transamidase subunit PIG-U ABC2_membrane_3 PF12698.2 AIO00421.1 - 0.033 13.2 0.2 0.033 13.2 0.1 2.4 2 1 0 2 2 2 0 ABC-2 family transporter protein Peptidase_C2 PF00648.16 AIO00422.1 - 7.3e-24 84.2 0.6 2.9e-12 46.1 0.0 4.1 4 0 0 4 4 4 3 Calpain family cysteine protease Calpain_III PF01067.17 AIO00422.1 - 8.9e-09 35.1 0.0 0.00044 19.9 0.0 2.7 2 0 0 2 2 2 2 Calpain large subunit, domain III LRR_6 PF13516.1 AIO00422.1 - 0.00012 21.8 1.2 1.9 8.7 0.0 3.7 3 0 0 3 3 3 1 Leucine Rich repeat LRR_4 PF12799.2 AIO00422.1 - 0.053 13.1 4.3 0.065 12.8 1.0 2.4 1 1 2 3 3 3 0 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 AIO00422.1 - 0.18 11.9 4.8 8.5 6.8 0.2 3.8 3 0 0 3 3 3 0 Leucine Rich Repeat LRR_8 PF13855.1 AIO00422.1 - 0.97 9.2 3.4 37 4.1 0.1 2.5 1 1 1 2 2 2 0 Leucine rich repeat Cytochrom_B561 PF03188.11 AIO00423.1 - 1.8e-11 44.0 2.5 5.9e-10 39.1 0.8 2.2 2 0 0 2 2 2 2 Eukaryotic cytochrome b561 zf-C3HC4_2 PF13923.1 AIO00424.1 - 0.003 17.5 10.8 0.003 17.5 7.5 3.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) DUF814 PF05670.8 AIO00426.1 - 2.9e-22 78.3 0.0 4.7e-22 77.6 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF814) YscJ_FliF PF01514.12 AIO00426.1 - 0.079 12.1 0.0 0.12 11.5 0.0 1.2 1 0 0 1 1 1 0 Secretory protein of YscJ/FliF family T2SE PF00437.15 AIO00427.1 - 0.0058 15.5 0.1 0.019 13.8 0.0 1.9 2 0 0 2 2 2 1 Type II/IV secretion system protein NACHT PF05729.7 AIO00427.1 - 0.0085 15.7 0.0 0.023 14.3 0.0 1.7 1 1 0 1 1 1 1 NACHT domain AAA_22 PF13401.1 AIO00427.1 - 0.01 15.9 0.1 0.065 13.3 0.0 2.2 2 1 0 2 2 2 0 AAA domain AAA_16 PF13191.1 AIO00427.1 - 0.014 15.3 0.6 0.029 14.3 0.0 1.9 2 1 0 2 2 2 0 AAA ATPase domain AAA_25 PF13481.1 AIO00427.1 - 0.044 13.1 0.2 0.27 10.6 0.0 2.2 2 0 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.13 AIO00427.1 - 0.094 12.1 0.1 0.34 10.3 0.0 1.9 2 0 0 2 2 2 0 FtsK/SpoIIIE family Fe-ADH PF00465.14 AIO00428.1 - 2.1e-106 355.6 0.2 2.4e-106 355.4 0.1 1.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.1 AIO00428.1 - 2e-18 66.5 0.1 7.1e-12 45.1 0.0 2.1 2 0 0 2 2 2 2 Iron-containing alcohol dehydrogenase DUF1664 PF07889.7 AIO00429.1 - 0.0018 18.0 1.1 0.0039 16.9 0.8 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1664) Apolipoprotein PF01442.13 AIO00429.1 - 0.011 15.1 3.4 0.014 14.8 1.2 2.0 2 0 0 2 2 2 0 Apolipoprotein A1/A4/E domain FlgN PF05130.7 AIO00429.1 - 0.026 14.7 7.1 0.04 14.1 3.2 2.5 3 0 0 3 3 3 0 FlgN protein Baculo_PEP_C PF04513.7 AIO00429.1 - 0.045 13.5 2.0 0.1 12.3 1.4 1.5 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Salp15 PF12115.3 AIO00429.1 - 0.098 12.8 1.3 0.25 11.5 0.8 1.8 1 1 0 1 1 1 0 Salivary protein of 15kDa inhibits CD4+ T cell activation DUF148 PF02520.12 AIO00429.1 - 0.12 12.2 5.3 0.22 11.3 3.7 1.4 1 0 0 1 1 1 0 Domain of unknown function DUF148 ARL2_Bind_BART PF11527.3 AIO00429.1 - 0.16 11.7 1.8 0.34 10.7 1.2 1.4 1 0 0 1 1 1 0 The ARF-like 2 binding protein BART DUF4164 PF13747.1 AIO00429.1 - 0.44 10.7 4.0 0.25 11.5 0.4 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4164) Hpt PF01627.18 AIO00429.1 - 8.6 6.4 10.1 4 7.5 0.3 3.2 2 2 0 2 2 2 0 Hpt domain Oligomerisation PF02410.10 AIO00431.1 - 2.5e-15 56.3 0.7 3.5e-15 55.8 0.5 1.2 1 0 0 1 1 1 1 Oligomerisation domain DUF3548 PF12068.3 AIO00431.1 - 0.01 15.1 0.0 3.7 6.7 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3548) Pkinase PF00069.20 AIO00432.1 - 5.8e-52 176.4 0.1 1.4e-38 132.5 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 AIO00432.1 - 3.6e-36 124.5 0.1 5.1e-29 101.1 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Beta_helix PF13229.1 AIO00432.1 - 2e-28 99.1 11.2 5.5e-16 58.7 0.6 3.3 1 1 1 2 2 2 2 Right handed beta helix region NosD PF05048.8 AIO00432.1 - 1.1e-24 86.9 0.5 1e-14 54.3 0.3 2.3 1 1 1 2 2 2 2 Periplasmic copper-binding protein (NosD) Kinase-like PF14531.1 AIO00432.1 - 6.6e-08 31.8 0.2 4.1e-07 29.2 0.0 2.0 2 0 0 2 2 2 1 Kinase-like DUF1565 PF07602.6 AIO00432.1 - 0.00028 20.1 5.6 0.016 14.3 2.3 2.5 1 1 1 2 2 2 2 Protein of unknown function (DUF1565) Patatin PF01734.17 AIO00433.1 - 3.8e-24 85.7 0.9 5.7e-24 85.1 0.0 1.8 2 0 0 2 2 2 1 Patatin-like phospholipase DUF3336 PF11815.3 AIO00433.1 - 2.6e-13 49.6 0.0 5e-13 48.7 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3336) WD40 PF00400.27 AIO00434.1 - 1.7e-12 46.6 4.0 0.00014 21.5 0.0 7.1 6 1 1 7 7 7 5 WD domain, G-beta repeat IBR PF01485.16 AIO00436.1 - 3.9e-12 45.8 46.7 4.6e-09 36.0 9.7 4.4 3 1 1 4 4 4 2 IBR domain zf-RING_2 PF13639.1 AIO00436.1 - 4.5e-05 23.1 46.2 0.00016 21.4 9.3 3.8 2 1 1 3 3 3 2 Ring finger domain zf-RING_5 PF14634.1 AIO00436.1 - 0.018 14.7 12.5 0.018 14.7 8.7 4.2 2 1 1 3 3 3 0 zinc-RING finger domain UBA_4 PF14555.1 AIO00436.1 - 0.085 12.4 0.0 0.34 10.4 0.0 2.0 2 0 0 2 2 2 0 UBA-like domain zf-C3HC4 PF00097.20 AIO00436.1 - 6.6 6.4 41.6 0.1 12.2 7.4 3.7 3 1 1 4 4 4 0 Zinc finger, C3HC4 type (RING finger) RRM_1 PF00076.17 AIO00437.1 - 6.2e-22 77.0 0.0 4.4e-12 45.4 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 AIO00437.1 - 1.9e-12 46.9 0.0 4.6e-07 29.7 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 AIO00437.1 - 3.6e-06 26.7 0.0 0.00083 19.1 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TIR-like PF10137.4 AIO00437.1 - 0.16 11.5 0.0 0.33 10.5 0.0 1.4 1 0 0 1 1 1 0 Predicted nucleotide-binding protein containing TIR-like domain Caldesmon PF02029.10 AIO00437.1 - 0.35 9.2 4.3 0.46 8.8 3.0 1.1 1 0 0 1 1 1 0 Caldesmon RRM_1 PF00076.17 AIO00438.1 - 2.9e-25 87.6 0.7 5.3e-15 54.7 0.1 3.3 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 AIO00438.1 - 4.3e-17 61.8 0.2 6.8e-09 35.5 0.0 2.9 3 0 0 3 3 3 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 AIO00438.1 - 4e-07 29.7 0.2 0.0013 18.5 0.0 2.8 2 1 1 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCCH PF00642.19 AIO00439.1 - 2.6e-07 30.1 0.5 3.7e-07 29.6 0.3 1.2 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.1 AIO00439.1 - 0.075 13.0 1.6 0.19 11.8 1.1 1.7 1 1 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type DUF4339 PF14237.1 AIO00440.1 - 5.3e-16 57.9 0.1 1.2e-15 56.7 0.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4339) DnaJ PF00226.26 AIO00440.1 - 8.3e-15 54.2 0.4 1.9e-14 53.1 0.3 1.6 1 0 0 1 1 1 1 DnaJ domain SpoU_methylas_C PF12105.3 AIO00440.1 - 0.044 13.3 0.0 3.4 7.2 0.0 2.9 2 0 0 2 2 2 0 SpoU, rRNA methylase, C-terminal CDC14 PF08045.6 AIO00440.1 - 0.055 12.6 3.6 0.053 12.6 0.3 2.5 4 0 0 4 4 4 0 Cell division control protein 14, SIN component DUF155 PF02582.9 AIO00441.1 - 8.5e-20 71.3 0.0 1.8e-19 70.3 0.0 1.5 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 Mito_carr PF00153.22 AIO00443.1 - 2.1e-11 43.4 6.9 0.0025 17.4 0.1 4.8 4 1 0 4 4 4 4 Mitochondrial carrier protein Tim17 PF02466.14 AIO00443.1 - 0.39 10.7 3.4 1.4 9.0 0.0 2.8 3 1 0 3 3 3 0 Tim17/Tim22/Tim23/Pmp24 family CytB6-F_Fe-S PF08802.5 AIO00443.1 - 4.6 7.3 6.1 0.53 10.3 0.6 2.2 2 0 0 2 2 2 0 Cytochrome B6-F complex Fe-S subunit zf-C2H2_2 PF12756.2 AIO00444.1 - 4.7e-26 90.8 10.3 1.6e-19 69.8 1.1 3.2 3 0 0 3 3 3 2 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.3 AIO00444.1 - 2.3e-10 40.3 7.5 2.3e-06 27.5 0.1 3.9 3 1 0 3 3 3 3 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 AIO00444.1 - 4.6e-09 36.1 12.2 3.3e-05 23.9 0.8 3.8 3 1 0 3 3 3 2 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.1 AIO00444.1 - 4e-08 32.8 2.7 0.003 17.3 0.2 3.6 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_4 PF13894.1 AIO00444.1 - 0.00015 21.8 16.3 0.0052 17.0 0.7 4.4 4 0 0 4 4 4 2 C2H2-type zinc finger zf-C2H2 PF00096.21 AIO00444.1 - 0.0006 19.9 19.2 0.0029 17.8 0.8 4.4 4 0 0 4 4 4 2 Zinc finger, C2H2 type Hydrolase PF00702.21 AIO00445.1 - 1.2e-12 48.7 0.0 2.8e-07 31.1 0.0 2.7 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.15 AIO00445.1 - 1.7e-11 43.6 0.0 3.2e-11 42.7 0.0 1.4 1 0 0 1 1 1 1 E1-E2 ATPase HAD PF12710.2 AIO00445.1 - 8.8e-09 35.7 0.0 4.9e-08 33.3 0.0 2.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 AIO00445.1 - 4.5e-07 29.7 0.0 1.1e-06 28.4 0.0 1.6 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 AIO00445.1 - 0.03 13.8 0.0 0.076 12.5 0.0 1.6 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase LRR_4 PF12799.2 AIO00446.1 - 3.4e-16 58.4 10.4 1.2e-05 24.8 0.7 7.3 5 2 1 6 6 6 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 AIO00446.1 - 2.4e-11 43.1 17.7 1.5e-06 27.8 0.4 5.8 3 2 3 6 6 6 5 Leucine rich repeat LRR_1 PF00560.28 AIO00446.1 - 4.5e-05 22.9 13.8 5.9 7.3 0.5 8.4 6 2 0 6 6 6 1 Leucine Rich Repeat LRR_7 PF13504.1 AIO00446.1 - 0.034 14.3 27.2 7 7.3 0.3 9.6 10 0 0 10 10 10 0 Leucine rich repeat LRR_6 PF13516.1 AIO00446.1 - 8.5 6.7 14.7 9.9 6.5 0.1 6.5 8 0 0 8 8 8 0 Leucine Rich repeat TTL PF03133.10 AIO00447.1 - 4.1e-48 163.8 0.0 1.6e-29 102.7 0.0 3.1 2 1 0 3 3 3 3 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.1 AIO00447.1 - 0.00017 20.5 0.0 0.49 9.1 0.0 2.4 2 0 0 2 2 2 2 YheC/D like ATP-grasp ATPgrasp_ST PF14397.1 AIO00447.1 - 0.0006 18.9 0.0 0.11 11.5 0.0 2.2 2 0 0 2 2 2 2 Sugar-transfer associated ATP-grasp CP_ATPgrasp_1 PF04174.8 AIO00447.1 - 0.0022 16.6 0.0 0.0038 15.8 0.0 1.3 1 0 0 1 1 1 1 A circularly permuted ATPgrasp Dala_Dala_lig_C PF07478.8 AIO00447.1 - 0.067 12.5 0.0 0.16 11.3 0.0 1.6 1 0 0 1 1 1 0 D-ala D-ala ligase C-terminus Helicase_C PF00271.26 AIO00448.1 - 1.5e-14 53.6 0.2 3.9e-14 52.2 0.2 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 AIO00448.1 - 1.9e-13 50.2 0.0 1.2e-12 47.6 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase DUF742 PF05331.6 AIO00448.1 - 0.0096 15.5 0.0 0.037 13.6 0.0 2.0 1 0 0 1 1 1 1 Protein of unknown function (DUF742) HTH_24 PF13412.1 AIO00448.1 - 0.14 11.5 0.0 0.47 9.8 0.0 1.9 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding SET PF00856.23 AIO00451.1 - 0.00021 21.6 0.0 0.00057 20.2 0.0 1.7 2 1 0 2 2 2 1 SET domain Cep57_MT_bd PF06657.8 AIO00452.1 - 0.054 13.4 0.4 0.2 11.6 0.0 2.0 2 0 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 Abhydrolase_5 PF12695.2 AIO00452.1 - 0.089 12.5 0.0 0.12 12.1 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family DUF724 PF05266.9 AIO00452.1 - 5.5 6.5 7.5 1 8.9 0.5 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF724) DUF1068 PF06364.7 AIO00453.1 - 0.031 13.9 0.6 0.073 12.6 0.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1068) Pyridoxal_deC PF00282.14 AIO00454.1 - 3.4e-19 68.5 0.0 6.8e-19 67.5 0.0 1.4 1 1 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.14 AIO00454.1 - 2.1e-10 39.8 0.0 8.9e-10 37.8 0.0 1.9 1 1 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.12 AIO00454.1 - 0.033 13.2 0.0 0.053 12.5 0.0 1.2 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family zf-C3HC4_4 PF15227.1 AIO00455.1 - 1.3e-09 37.7 7.8 1.3e-09 37.7 5.4 3.9 3 1 1 4 4 4 1 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.20 AIO00455.1 - 4.7e-09 35.7 7.0 4.7e-09 35.7 4.8 3.3 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-B_box PF00643.19 AIO00455.1 - 7.4e-08 32.1 23.6 8.9e-07 28.6 5.9 4.7 5 0 0 5 5 5 2 B-box zinc finger zf-RING_2 PF13639.1 AIO00455.1 - 9.2e-07 28.5 5.8 9.2e-07 28.5 4.0 3.8 3 1 1 4 4 4 1 Ring finger domain zf-RING_5 PF14634.1 AIO00455.1 - 1.6e-06 27.7 6.6 1.6e-06 27.7 4.6 3.7 3 0 0 3 3 3 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 AIO00455.1 - 1.8e-06 27.8 7.5 1.8e-06 27.8 5.2 3.5 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) Spc7 PF08317.6 AIO00455.1 - 0.026 13.2 0.9 0.04 12.5 0.6 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein Flg_hook PF02120.11 AIO00455.1 - 0.13 11.8 3.9 0.065 12.9 0.4 2.1 2 1 1 3 3 3 0 Flagellar hook-length control protein FliK zf-RING_UBOX PF13445.1 AIO00455.1 - 2.5 7.8 17.4 0.043 13.5 3.1 3.2 2 1 0 2 2 2 0 RING-type zinc-finger Arf PF00025.16 AIO00456.1 - 9.2e-48 161.7 0.0 1e-47 161.6 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 AIO00456.1 - 2.8e-17 62.5 0.0 3.5e-17 62.1 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.17 AIO00456.1 - 1e-09 37.9 0.0 1.4e-09 37.5 0.0 1.1 1 0 0 1 1 1 1 Ras family MMR_HSR1 PF01926.18 AIO00456.1 - 2.2e-09 37.2 0.0 3e-09 36.8 0.0 1.1 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 AIO00456.1 - 4.3e-09 36.8 0.0 5.6e-09 36.5 0.0 1.1 1 0 0 1 1 1 1 Miro-like protein G-alpha PF00503.15 AIO00456.1 - 9.4e-09 34.4 0.0 1.4e-05 23.9 0.0 2.2 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.7 AIO00456.1 - 7.6e-06 25.2 0.0 9.9e-06 24.8 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 AIO00456.1 - 0.0014 18.1 0.0 0.013 14.9 0.0 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.13 AIO00456.1 - 0.0018 17.5 0.1 0.0043 16.3 0.0 1.7 1 1 0 1 1 1 1 Ferrous iron transport protein B Arch_ATPase PF01637.13 AIO00456.1 - 0.032 13.9 0.0 0.054 13.1 0.0 1.3 1 0 0 1 1 1 0 Archaeal ATPase AAA_14 PF13173.1 AIO00456.1 - 0.15 11.9 0.0 0.89 9.4 0.0 1.9 2 0 0 2 2 2 0 AAA domain cobW PF02492.14 AIO00456.1 - 0.25 10.7 2.2 4.6 6.6 0.1 2.3 1 1 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Reo_sigmaC PF04582.7 AIO00457.1 - 0.0017 17.5 0.9 0.0017 17.5 0.6 2.4 1 1 0 2 2 2 1 Reovirus sigma C capsid protein Rnk_N PF14760.1 AIO00457.1 - 0.11 12.5 6.0 0.22 11.5 0.1 3.7 4 0 0 4 4 4 0 Rnk N-terminus APCDDC PF14921.1 AIO00457.1 - 0.72 9.1 4.3 1.7 7.9 3.0 1.7 1 1 0 1 1 1 0 Adenomatosis polyposis coli down-regulated 1 PTH2 PF01981.11 AIO00457.1 - 1 9.0 7.1 0.45 10.2 0.3 2.9 2 1 1 4 4 4 0 Peptidyl-tRNA hydrolase PTH2 OpgC_C PF10129.4 AIO00459.1 - 0.0041 15.8 2.8 0.0055 15.4 1.9 1.2 1 0 0 1 1 1 1 OpgC protein Clp1 PF06807.9 AIO00460.1 - 1.3e-13 51.1 0.0 8.8e-13 48.4 0.0 2.0 1 1 0 1 1 1 1 Pre-mRNA cleavage complex II protein Clp1 PTH2 PF01981.11 AIO00461.1 - 4.4e-14 52.1 0.1 8.8e-14 51.1 0.0 1.5 1 1 0 1 1 1 1 Peptidyl-tRNA hydrolase PTH2 DUF397 PF04149.7 AIO00461.1 - 0.054 13.0 0.6 0.12 11.9 0.2 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF397) TPR_11 PF13414.1 AIO00463.1 - 2.5e-07 30.2 0.0 5.5e-06 25.9 0.0 2.3 2 0 0 2 2 2 1 TPR repeat TPR_2 PF07719.12 AIO00463.1 - 1.3e-05 24.7 0.1 0.075 12.9 0.0 2.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.23 AIO00463.1 - 0.0037 16.7 0.1 0.63 9.7 0.0 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.1 AIO00463.1 - 0.024 14.5 0.6 0.05 13.5 0.4 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat Rad50_zn_hook PF04423.9 AIO00463.1 - 0.14 11.6 0.4 0.41 10.1 0.3 1.8 1 0 0 1 1 1 0 Rad50 zinc hook motif TPR_8 PF13181.1 AIO00463.1 - 0.15 11.8 0.0 1.7 8.6 0.0 2.7 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF2256 PF10013.4 AIO00463.1 - 0.32 10.7 5.8 4 7.2 0.4 2.4 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2256) DnaJ PF00226.26 AIO00464.1 - 4.5e-14 51.9 0.0 1.1e-13 50.6 0.0 1.7 1 0 0 1 1 1 1 DnaJ domain Plasmodium_Vir PF05795.6 AIO00464.1 - 0.00014 21.1 0.1 0.00019 20.7 0.0 1.1 1 0 0 1 1 1 1 Plasmodium vivax Vir protein BLUF PF04940.7 AIO00464.1 - 0.078 12.7 0.0 0.19 11.4 0.0 1.6 1 0 0 1 1 1 0 Sensors of blue-light using FAD Viral_Beta_CD PF04530.7 AIO00464.1 - 0.085 13.0 0.0 0.17 12.0 0.0 1.5 1 0 0 1 1 1 0 Viral Beta C/D like family HSP70 PF00012.15 AIO00465.1 - 1.8e-248 825.3 5.2 2.1e-248 825.1 3.6 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 AIO00465.1 - 1.1e-13 50.4 1.0 2e-12 46.3 0.2 2.6 2 1 0 2 2 2 1 MreB/Mbl protein StbA PF06406.6 AIO00465.1 - 0.00069 18.6 0.8 0.71 8.7 0.0 3.6 3 1 1 4 4 4 2 StbA protein PIN_3 PF13470.1 AIO00465.1 - 0.0073 16.9 1.0 0.41 11.3 0.0 2.4 2 0 0 2 2 2 1 PIN domain FtsA PF14450.1 AIO00465.1 - 0.081 12.7 9.1 0.6 9.9 0.0 4.3 4 1 0 4 4 4 0 Cell division protein FtsA Pyridoxal_deC PF00282.14 AIO00466.1 - 1.1e-103 346.6 0.0 1.3e-103 346.3 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Beta_elim_lyase PF01212.16 AIO00466.1 - 3.4e-06 26.4 0.1 4.5e-06 26.0 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase SLA_LP_auto_ag PF05889.8 AIO00466.1 - 0.042 12.3 0.1 0.24 9.8 0.1 1.9 2 0 0 2 2 2 0 Soluble liver antigen/liver pancreas antigen (SLA/LP autoantigen) AAA PF00004.24 AIO00469.1 - 4e-47 159.7 0.0 2.6e-40 137.6 0.0 2.8 2 1 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 AIO00469.1 - 4e-05 23.7 0.1 0.25 11.4 0.0 3.3 2 1 1 3 3 3 2 AAA domain AAA_16 PF13191.1 AIO00469.1 - 7.4e-05 22.8 4.8 0.14 12.1 0.0 4.0 2 2 1 3 3 3 1 AAA ATPase domain AAA_5 PF07728.9 AIO00469.1 - 0.00032 20.4 0.0 0.035 13.8 0.0 3.5 4 1 0 4 4 3 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.7 AIO00469.1 - 0.00041 19.4 0.0 0.001 18.1 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_25 PF13481.1 AIO00469.1 - 0.00089 18.7 3.4 0.56 9.5 0.0 4.1 2 2 1 3 3 3 1 AAA domain IstB_IS21 PF01695.12 AIO00469.1 - 0.0014 18.0 0.1 0.15 11.4 0.0 2.4 2 0 0 2 2 2 1 IstB-like ATP binding protein Zeta_toxin PF06414.7 AIO00469.1 - 0.0028 16.7 0.0 0.2 10.7 0.0 2.9 3 0 0 3 3 3 1 Zeta toxin Vps4_C PF09336.5 AIO00469.1 - 0.0028 17.4 0.0 0.016 15.0 0.0 2.2 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain TIP49 PF06068.8 AIO00469.1 - 0.0037 16.0 0.0 0.0078 14.9 0.0 1.5 1 0 0 1 1 1 1 TIP49 C-terminus AAA_33 PF13671.1 AIO00469.1 - 0.0053 16.6 0.3 1.2 8.9 0.0 3.1 3 0 0 3 3 3 1 AAA domain RNA_helicase PF00910.17 AIO00469.1 - 0.0078 16.3 0.0 0.36 11.0 0.0 2.5 2 0 0 2 2 2 1 RNA helicase ABC_tran PF00005.22 AIO00469.1 - 0.02 15.2 0.0 2.2 8.5 0.0 2.4 2 0 0 2 2 2 0 ABC transporter AAA_2 PF07724.9 AIO00469.1 - 0.021 14.7 0.0 0.066 13.1 0.0 1.8 2 0 0 2 2 1 0 AAA domain (Cdc48 subfamily) Mg_chelatase PF01078.16 AIO00469.1 - 0.024 13.7 0.0 0.062 12.4 0.0 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Sigma54_activ_2 PF14532.1 AIO00469.1 - 0.07 13.1 0.0 0.15 12.1 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_17 PF13207.1 AIO00469.1 - 0.072 13.9 0.2 1.3 9.8 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.1 AIO00469.1 - 0.087 12.7 0.5 0.51 10.2 0.0 2.5 2 1 1 3 3 3 0 AAA domain Rad17 PF03215.10 AIO00469.1 - 0.1 11.2 0.0 0.15 10.7 0.0 1.1 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein NACHT PF05729.7 AIO00469.1 - 0.13 11.9 0.0 3 7.4 0.0 2.5 3 0 0 3 3 2 0 NACHT domain AAA_14 PF13173.1 AIO00469.1 - 0.13 12.1 0.0 0.39 10.6 0.0 1.8 2 0 0 2 2 2 0 AAA domain Arch_ATPase PF01637.13 AIO00469.1 - 0.27 10.8 0.1 11 5.6 0.0 2.6 2 2 1 3 3 3 0 Archaeal ATPase HSP70 PF00012.15 AIO00470.1 - 4.5e-259 860.4 8.6 5.3e-259 860.2 6.0 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 AIO00470.1 - 1.3e-13 50.3 1.0 2.2e-12 46.2 0.2 2.6 2 1 0 2 2 2 1 MreB/Mbl protein PIN_3 PF13470.1 AIO00470.1 - 0.0055 17.3 0.6 0.43 11.2 0.0 2.4 2 0 0 2 2 2 1 PIN domain FtsA PF14450.1 AIO00470.1 - 0.021 14.6 9.8 0.64 9.8 0.0 4.6 4 1 0 4 4 4 0 Cell division protein FtsA AAA_13 PF13166.1 AIO00471.1 - 0.98 7.7 4.4 1.8 6.9 3.1 1.3 1 0 0 1 1 1 0 AAA domain Mnd1 PF03962.10 AIO00471.1 - 2.8 7.5 7.9 1.4 8.5 3.0 2.3 2 0 0 2 2 2 0 Mnd1 family Cofilin_ADF PF00241.15 AIO00472.1 - 0.0023 17.8 0.0 0.03 14.2 0.0 2.2 2 0 0 2 2 2 1 Cofilin/tropomyosin-type actin-binding protein Reticulon PF02453.12 AIO00473.1 - 1.5e-35 122.2 9.8 2e-35 121.9 6.8 1.2 1 0 0 1 1 1 1 Reticulon DUF3292 PF11696.3 AIO00473.1 - 0.0075 14.2 0.4 0.01 13.7 0.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3292) Connexin_CCC PF10582.4 AIO00473.1 - 0.74 9.6 4.2 0.2 11.4 0.3 2.1 2 0 0 2 2 2 0 Gap junction channel protein cysteine-rich domain DUF1212 PF06738.7 AIO00473.1 - 3.8 6.9 8.1 2 7.8 1.9 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1212) Leu_Phe_trans PF03588.9 AIO00474.1 - 6.1e-06 25.4 0.1 5e-05 22.5 0.1 2.0 1 1 0 1 1 1 1 Leucyl/phenylalanyl-tRNA protein transferase FTHFS PF01268.14 AIO00475.1 - 1.3e-257 855.3 0.1 1.4e-257 855.1 0.1 1.0 1 0 0 1 1 1 1 Formate--tetrahydrofolate ligase RRM_1 PF00076.17 AIO00476.1 - 1.8e-16 59.5 0.0 3.3e-16 58.6 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 AIO00476.1 - 1.2e-15 57.1 0.0 2.7e-15 56.1 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 AIO00476.1 - 1.1e-09 38.0 0.0 1.6e-09 37.4 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 AIO00476.1 - 0.0047 16.6 0.0 0.0078 15.9 0.0 1.3 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif ORF6C PF10552.4 AIO00476.1 - 0.054 13.2 0.1 0.085 12.5 0.0 1.2 1 0 0 1 1 1 0 ORF6C domain AAA PF00004.24 AIO00479.1 - 1.9e-13 50.7 0.0 4.1e-13 49.6 0.0 1.6 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Rep_fac_C PF08542.6 AIO00479.1 - 6.3e-10 38.8 0.0 1.1e-09 38.0 0.0 1.4 1 0 0 1 1 1 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.1 AIO00479.1 - 8.3e-08 32.0 0.0 1.4e-06 28.0 0.0 2.3 1 1 0 1 1 1 1 DNA polymerase III, delta subunit AAA_22 PF13401.1 AIO00479.1 - 7.7e-06 26.0 0.0 6.7e-05 23.0 0.0 2.2 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 AIO00479.1 - 0.00019 21.0 0.0 0.00052 19.7 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain AAA_11 PF13086.1 AIO00479.1 - 0.0003 20.4 0.0 0.0012 18.4 0.0 1.7 1 1 1 2 2 2 1 AAA domain AAA_16 PF13191.1 AIO00479.1 - 0.00043 20.3 1.2 0.02 14.8 0.0 3.0 1 1 1 3 3 3 1 AAA ATPase domain DUF2075 PF09848.4 AIO00479.1 - 0.00061 18.8 0.0 0.00089 18.3 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_33 PF13671.1 AIO00479.1 - 0.0041 17.0 0.0 0.0077 16.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.7 AIO00479.1 - 0.0085 15.1 0.0 0.023 13.7 0.0 1.9 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_5 PF07728.9 AIO00479.1 - 0.0094 15.6 0.0 0.022 14.4 0.0 1.6 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_14 PF13173.1 AIO00479.1 - 0.013 15.3 0.0 0.028 14.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.1 AIO00479.1 - 0.02 14.8 0.0 0.037 13.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.1 AIO00479.1 - 0.036 13.4 0.2 0.67 9.3 0.0 2.3 1 1 1 2 2 2 0 AAA domain AAA_30 PF13604.1 AIO00479.1 - 0.044 13.3 0.0 0.083 12.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain Viral_helicase1 PF01443.13 AIO00479.1 - 0.065 12.7 0.0 0.13 11.7 0.0 1.6 1 1 0 1 1 1 0 Viral (Superfamily 1) RNA helicase DEAD PF00270.24 AIO00479.1 - 0.088 12.2 0.0 0.94 8.9 0.0 2.2 2 0 0 2 2 2 0 DEAD/DEAH box helicase AAA_23 PF13476.1 AIO00479.1 - 0.13 12.6 0.0 0.18 12.1 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_10 PF12846.2 AIO00479.1 - 0.14 11.5 0.0 2.3 7.5 0.0 2.2 2 0 0 2 2 2 0 AAA-like domain DUF3136 PF11334.3 AIO00480.1 - 0.084 12.3 0.2 2.8 7.4 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3136) ubiquitin PF00240.18 AIO00482.1 - 0.0015 17.8 0.0 0.0029 16.9 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family IL10 PF00726.12 AIO00482.1 - 0.13 11.5 0.1 0.19 11.0 0.1 1.2 1 0 0 1 1 1 0 Interleukin 10 TPR_12 PF13424.1 AIO00483.1 - 0.00017 21.4 1.7 0.0099 15.8 0.0 3.3 3 1 0 3 3 3 2 Tetratricopeptide repeat DUF3551 PF12071.3 AIO00484.1 - 0.004 16.6 0.5 7.5 6.1 0.0 3.2 3 0 0 3 3 3 2 Protein of unknown function (DUF3551) ATG27 PF09451.5 AIO00484.1 - 0.2 10.8 0.0 0.29 10.3 0.0 1.1 1 0 0 1 1 1 0 Autophagy-related protein 27 SH3_2 PF07653.12 AIO00485.1 - 4.1e-07 29.3 0.0 6.6e-07 28.7 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.1 AIO00485.1 - 1.1e-06 28.1 0.0 1.6e-06 27.5 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 AIO00485.1 - 0.00011 21.4 0.0 0.00022 20.5 0.0 1.5 1 0 0 1 1 1 1 SH3 domain Tmemb_cc2 PF10267.4 AIO00485.1 - 0.13 10.8 1.0 0.2 10.1 0.7 1.3 1 1 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein GRAM PF02893.15 AIO00488.1 - 7.2e-08 31.8 0.0 1.4e-07 30.9 0.0 1.5 1 0 0 1 1 1 1 GRAM domain Cut8_N PF14482.1 AIO00488.1 - 0.13 12.2 0.4 0.28 11.1 0.3 1.5 1 0 0 1 1 1 0 Cut8 proteasome-binding domain SPA PF08616.5 AIO00489.1 - 2.5e-29 101.2 0.0 5.2e-29 100.2 0.0 1.6 1 0 0 1 1 1 1 Stabilization of polarity axis DUF2347 PF09804.4 AIO00489.1 - 9.4e-05 21.8 0.0 0.00014 21.2 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2347) Avl9 PF09794.4 AIO00489.1 - 0.00042 18.9 0.0 0.021 13.2 0.0 2.2 1 1 1 2 2 2 2 Transport protein Avl9 DENN PF02141.16 AIO00489.1 - 0.001 18.8 0.1 0.0037 17.0 0.0 2.1 2 0 0 2 2 2 1 DENN (AEX-3) domain TPR_11 PF13414.1 AIO00490.1 - 4.9e-26 90.1 6.4 1.3e-18 66.4 1.2 2.6 2 0 0 2 2 2 2 TPR repeat TPR_1 PF00515.23 AIO00490.1 - 7.8e-25 85.4 7.7 7.7e-08 31.6 0.0 4.0 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.12 AIO00490.1 - 3.4e-17 60.9 14.8 2e-07 30.4 0.0 4.7 5 0 0 5 5 4 3 Tetratricopeptide repeat TPR_16 PF13432.1 AIO00490.1 - 5.7e-10 39.5 2.5 3.4e-06 27.5 0.1 3.0 2 1 2 4 4 3 3 Tetratricopeptide repeat TPR_12 PF13424.1 AIO00490.1 - 7.9e-10 38.5 5.4 4e-06 26.6 0.2 2.5 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_17 PF13431.1 AIO00490.1 - 9.3e-10 37.9 2.7 0.00096 19.1 0.0 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.1 AIO00490.1 - 2.1e-09 36.4 2.5 0.0062 16.2 0.0 3.9 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_8 PF13181.1 AIO00490.1 - 5.6e-08 32.0 5.5 0.013 15.1 0.0 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.1 AIO00490.1 - 1.5e-07 31.4 0.8 0.013 16.1 0.0 4.2 2 1 2 4 4 3 2 Tetratricopeptide repeat SGT1 PF07093.6 AIO00490.1 - 1.9e-06 26.5 0.5 2.9e-06 25.9 0.3 1.3 1 0 0 1 1 1 1 SGT1 protein TPR_19 PF14559.1 AIO00490.1 - 2.2e-06 27.9 4.1 0.012 15.9 0.1 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat Apc3 PF12895.2 AIO00490.1 - 0.00039 20.5 6.3 0.013 15.6 1.0 2.7 1 1 2 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.1 AIO00490.1 - 0.00043 20.0 0.2 0.021 14.6 0.1 2.3 1 1 1 2 2 2 2 Tetratricopeptide repeat TOM20_plant PF06552.7 AIO00490.1 - 0.00048 19.7 0.2 0.0039 16.7 0.1 2.6 2 1 1 3 3 3 1 Plant specific mitochondrial import receptor subunit TOM20 TPR_6 PF13174.1 AIO00490.1 - 0.011 16.1 3.1 0.7 10.4 0.1 3.6 4 0 0 4 4 3 0 Tetratricopeptide repeat MIT PF04212.13 AIO00490.1 - 0.055 13.3 4.7 0.46 10.3 0.4 3.1 3 0 0 3 3 3 0 MIT (microtubule interacting and transport) domain Sel1 PF08238.7 AIO00490.1 - 0.11 13.2 0.7 17 6.1 0.1 3.1 2 0 0 2 2 2 0 Sel1 repeat Fis1_TPR_C PF14853.1 AIO00490.1 - 0.13 12.1 2.6 7.6 6.5 0.0 3.2 3 0 0 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat Methyltransf_5 PF01795.14 AIO00491.1 - 0.016 14.5 1.0 0.023 13.9 0.7 1.2 1 0 0 1 1 1 0 MraW methylase family DSBA PF01323.15 AIO00491.1 - 0.065 12.7 0.8 0.1 12.1 0.5 1.2 1 0 0 1 1 1 0 DSBA-like thioredoxin domain TMA7 PF09072.5 AIO00492.1 - 2e-21 76.2 13.6 2.1e-21 76.1 9.4 1.0 1 0 0 1 1 1 1 Translation machinery associated TMA7 TLE_N PF03920.10 AIO00492.1 - 0.13 12.1 2.5 0.13 12.1 1.7 1.0 1 0 0 1 1 1 0 Groucho/TLE N-terminal Q-rich domain TFIIS_M PF07500.9 AIO00492.1 - 0.65 10.0 4.7 0.72 9.9 3.3 1.1 1 0 0 1 1 1 0 Transcription factor S-II (TFIIS), central domain Sod_Fe_N PF00081.17 AIO00494.1 - 4.3e-06 26.8 0.2 6.5e-06 26.3 0.2 1.3 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain Sod_Fe_C PF02777.13 AIO00494.1 - 0.00016 21.4 0.0 0.00045 20.0 0.0 1.8 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain CATSPERG PF15064.1 AIO00494.1 - 0.075 10.7 0.0 0.11 10.2 0.0 1.2 1 0 0 1 1 1 0 Cation channel sperm-associated protein subunit gamma zf-CCCH PF00642.19 AIO00495.1 - 3e-06 26.7 2.3 3e-06 26.7 1.6 2.0 2 0 0 2 2 2 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) MEDS PF14417.1 AIO00495.1 - 0.021 13.8 0.0 0.039 13.0 0.0 1.3 1 0 0 1 1 1 0 MEDS: MEthanogen/methylotroph, DcmR Sensory domain zf-CCCH_2 PF14608.1 AIO00495.1 - 0.083 12.9 1.7 0.19 11.8 1.2 1.6 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type DUF872 PF05915.7 AIO00496.1 - 1.6e-05 24.6 1.5 2.5e-05 24.0 1.0 1.3 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF872) TctB PF07331.6 AIO00496.1 - 0.067 12.8 3.0 0.094 12.3 2.1 1.1 1 0 0 1 1 1 0 Tripartite tricarboxylate transporter TctB family Claudin_2 PF13903.1 AIO00496.1 - 0.089 12.4 0.0 0.13 11.9 0.0 1.2 1 1 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction P22_CoatProtein PF11651.3 AIO00497.1 - 0.065 11.8 0.0 0.11 11.0 0.0 1.3 1 0 0 1 1 1 0 P22 coat protein - gene protein 5 Cpn60_TCP1 PF00118.19 AIO00499.1 - 3e-106 355.9 1.7 3.4e-106 355.7 1.2 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Guanylate_kin PF00625.16 AIO00499.1 - 0.11 11.8 0.1 0.48 9.8 0.0 2.0 2 0 0 2 2 2 0 Guanylate kinase RabGAP-TBC PF00566.13 AIO00501.1 - 3.3e-34 118.2 0.4 1.7e-33 115.9 0.3 1.9 1 1 0 1 1 1 1 Rab-GTPase-TBC domain DUF4597 PF15366.1 AIO00505.1 - 0.0028 17.2 0.4 0.0028 17.2 0.3 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4597) GAT PF03127.9 AIO00505.1 - 0.038 13.9 0.0 0.14 12.1 0.0 2.0 1 0 0 1 1 1 0 GAT domain EMP24_GP25L PF01105.19 AIO00505.1 - 0.22 11.2 0.3 0.37 10.4 0.2 1.3 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD PPR_3 PF13812.1 AIO00506.1 - 2.1e-05 24.4 16.4 0.046 14.0 0.0 7.0 8 0 0 8 8 8 2 Pentatricopeptide repeat domain Apc3 PF12895.2 AIO00506.1 - 3.5e-05 23.8 3.2 1 9.5 0.0 4.0 4 0 0 4 4 4 3 Anaphase-promoting complex, cyclosome, subunit 3 PPR_2 PF13041.1 AIO00506.1 - 5.7e-05 23.0 0.0 7.9 6.5 0.0 4.8 5 1 0 5 5 5 2 PPR repeat family TPR_7 PF13176.1 AIO00506.1 - 0.00032 20.2 2.0 80 3.4 0.0 5.9 5 0 0 5 5 5 0 Tetratricopeptide repeat PPR PF01535.15 AIO00506.1 - 0.0012 18.6 2.5 20 5.4 0.0 5.7 7 0 0 7 7 7 2 PPR repeat TPR_14 PF13428.1 AIO00506.1 - 5.6 7.8 18.7 11 6.9 0.0 6.5 6 2 1 7 7 7 0 Tetratricopeptide repeat Aldedh PF00171.17 AIO00508.1 - 3.4e-118 394.8 0.0 4.4e-118 394.5 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.6 AIO00508.1 - 0.0064 15.7 0.0 0.021 14.0 0.0 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF1487) Pkinase PF00069.20 AIO00509.1 - 1.6e-53 181.5 0.0 2e-53 181.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AIO00509.1 - 4.4e-18 65.2 0.0 6e-18 64.8 0.0 1.3 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 AIO00509.1 - 2.7e-06 26.5 0.1 5.1e-06 25.7 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 AIO00509.1 - 0.0011 18.7 0.2 0.0017 18.1 0.2 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.1 AIO00509.1 - 0.0013 17.7 0.0 0.0046 15.9 0.0 1.9 2 1 0 2 2 2 1 Kinase-like HALZ PF02183.13 AIO00510.1 - 0.053 13.2 5.2 0.86 9.3 0.2 3.1 2 0 0 2 2 2 0 Homeobox associated leucine zipper 4HB_MCP_1 PF12729.2 AIO00510.1 - 0.12 11.7 3.5 0.24 10.7 2.4 1.5 1 0 0 1 1 1 0 Four helix bundle sensory module for signal transduction zf-CHCC PF10276.4 AIO00513.1 - 3.8e-05 23.4 1.8 9.9e-05 22.0 1.3 1.8 1 0 0 1 1 1 1 Zinc-finger domain Gp_dh_C PF02800.15 AIO00514.1 - 2.5e-65 218.7 0.0 3.9e-65 218.1 0.0 1.3 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.19 AIO00514.1 - 6.2e-53 178.8 0.5 9.8e-53 178.1 0.3 1.3 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain DapB_N PF01113.15 AIO00514.1 - 0.0012 18.7 0.3 0.0049 16.7 0.2 2.2 1 1 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus GFO_IDH_MocA PF01408.17 AIO00514.1 - 0.06 13.8 0.0 0.11 13.0 0.0 1.4 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold DUF2817 PF10994.3 AIO00515.1 - 1.1e-104 350.1 0.2 1.3e-104 349.9 0.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2817) AstE_AspA PF04952.9 AIO00515.1 - 8.4e-05 21.5 0.0 0.00016 20.6 0.0 1.5 1 0 0 1 1 1 1 Succinylglutamate desuccinylase / Aspartoacylase family Peptidase_M14 PF00246.19 AIO00515.1 - 0.044 13.3 0.0 0.073 12.6 0.0 1.4 1 0 0 1 1 1 0 Zinc carboxypeptidase TPR_1 PF00515.23 AIO00517.1 - 1.6e-97 315.4 34.5 6.1e-08 31.9 0.5 15.0 15 0 0 15 15 15 14 Tetratricopeptide repeat TPR_11 PF13414.1 AIO00517.1 - 3.6e-97 318.0 44.5 9e-17 60.4 1.9 10.0 5 2 4 10 10 10 10 TPR repeat TPR_2 PF07719.12 AIO00517.1 - 7.1e-81 259.7 47.2 9e-07 28.3 0.5 15.6 15 0 0 15 15 15 14 Tetratricopeptide repeat TPR_16 PF13432.1 AIO00517.1 - 8.1e-45 150.6 53.0 4.7e-07 30.3 0.3 9.7 6 2 3 10 10 10 8 Tetratricopeptide repeat TPR_8 PF13181.1 AIO00517.1 - 2.9e-41 136.1 25.3 0.00032 20.2 0.5 13.0 13 1 1 14 14 14 9 Tetratricopeptide repeat TPR_17 PF13431.1 AIO00517.1 - 6.1e-41 135.2 29.2 0.00013 21.8 0.1 13.2 14 0 0 14 14 13 9 Tetratricopeptide repeat TPR_9 PF13371.1 AIO00517.1 - 2.1e-40 136.3 39.8 1.4e-05 24.8 0.1 12.1 3 3 10 13 13 13 12 Tetratricopeptide repeat TPR_12 PF13424.1 AIO00517.1 - 2.7e-34 116.9 47.3 2.4e-07 30.6 0.6 9.5 3 3 9 12 12 12 11 Tetratricopeptide repeat TPR_14 PF13428.1 AIO00517.1 - 5.2e-27 91.8 38.5 0.0046 17.4 0.0 14.7 3 2 12 15 15 15 11 Tetratricopeptide repeat TPR_7 PF13176.1 AIO00517.1 - 2.6e-24 83.0 28.2 0.0058 16.3 0.2 13.0 12 1 1 13 13 13 6 Tetratricopeptide repeat TPR_6 PF13174.1 AIO00517.1 - 2.2e-20 71.6 43.7 0.11 12.9 0.0 13.4 15 0 0 15 15 12 8 Tetratricopeptide repeat TPR_19 PF14559.1 AIO00517.1 - 7e-14 51.9 26.1 0.027 14.8 0.5 9.4 7 2 2 9 9 9 4 Tetratricopeptide repeat Apc3 PF12895.2 AIO00517.1 - 8.7e-09 35.4 35.7 0.025 14.7 1.3 8.0 3 2 6 10 10 10 5 Anaphase-promoting complex, cyclosome, subunit 3 SHNi-TPR PF10516.4 AIO00517.1 - 1.7e-08 33.5 14.2 1.3 8.3 0.1 9.7 10 0 0 10 10 10 2 SHNi-TPR Coatomer_E PF04733.9 AIO00517.1 - 0.0025 17.0 0.4 5.3 6.1 0.0 3.9 4 0 0 4 4 4 1 Coatomer epsilon subunit MIT PF04212.13 AIO00517.1 - 0.0073 16.1 30.2 0.84 9.5 0.2 9.2 9 3 2 11 11 11 3 MIT (microtubule interacting and transport) domain TPR_5 PF12688.2 AIO00517.1 - 0.011 15.8 14.6 11 6.1 0.0 7.3 6 1 2 8 8 8 0 Tetratrico peptide repeat NARP1 PF12569.3 AIO00517.1 - 0.035 12.8 12.6 0.079 11.7 0.1 4.5 2 1 3 5 5 5 0 NMDA receptor-regulated protein 1 DUF3856 PF12968.2 AIO00517.1 - 0.073 12.8 14.3 19 5.0 0.1 7.1 4 4 3 7 7 7 0 Domain of Unknown Function (DUF3856) T2SF PF00482.18 AIO00517.1 - 0.091 12.6 0.0 1.3 8.9 0.0 2.4 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein F Fis1_TPR_C PF14853.1 AIO00517.1 - 1.4 8.8 27.5 2.8 7.8 0.3 7.5 7 2 2 9 9 8 0 Fis1 C-terminal tetratricopeptide repeat BTAD PF03704.12 AIO00517.1 - 3.3 7.9 26.7 2.4 8.4 0.0 6.1 6 3 0 6 6 5 0 Bacterial transcriptional activator domain LSM PF01423.17 AIO00518.1 - 3.1e-07 29.8 0.5 5.3e-07 29.1 0.4 1.4 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 AIO00518.1 - 0.014 15.3 0.0 0.019 14.8 0.0 1.4 1 0 0 1 1 1 0 Ataxin 2 SM domain B_lectin PF01453.19 AIO00518.1 - 0.078 12.8 0.0 0.1 12.5 0.0 1.2 1 0 0 1 1 1 0 D-mannose binding lectin KH_1 PF00013.24 AIO00519.1 - 0.011 15.3 0.1 0.024 14.2 0.0 1.6 1 0 0 1 1 1 0 KH domain KH_3 PF13014.1 AIO00519.1 - 0.015 14.9 0.0 0.04 13.5 0.0 1.7 1 0 0 1 1 1 0 KH domain DUF4519 PF15012.1 AIO00519.1 - 0.029 14.2 5.9 0.078 12.8 4.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4519) DUF1513 PF07433.6 AIO00520.1 - 0.11 11.3 0.0 0.11 11.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1513) DUF21 PF01595.15 AIO00521.1 - 9.5e-24 83.6 4.8 1.7e-23 82.8 3.3 1.4 1 0 0 1 1 1 1 Domain of unknown function DUF21 CBS PF00571.23 AIO00521.1 - 2.5e-08 33.5 0.0 4.4e-05 23.1 0.0 2.6 2 0 0 2 2 2 2 CBS domain eIF-3_zeta PF05091.7 AIO00522.1 - 1.4e-120 403.3 0.0 1.6e-120 403.1 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Pkinase PF00069.20 AIO00523.1 - 3.2e-65 219.8 0.0 4.5e-65 219.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AIO00523.1 - 1.2e-44 152.3 0.0 1.8e-44 151.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 AIO00523.1 - 0.00022 20.2 0.0 0.00046 19.2 0.0 1.4 1 0 0 1 1 1 1 Kinase-like G8 PF10162.4 AIO00523.1 - 0.00032 20.4 0.2 1.1 9.1 0.0 2.9 2 0 0 2 2 2 2 G8 domain S-AdoMet_synt_C PF02773.11 AIO00523.1 - 0.014 15.1 0.0 0.037 13.7 0.0 1.6 1 0 0 1 1 1 0 S-adenosylmethionine synthetase, C-terminal domain Seadorna_VP7 PF07387.6 AIO00523.1 - 0.054 12.3 0.0 0.4 9.4 0.0 2.0 2 0 0 2 2 2 0 Seadornavirus VP7 HTH_Mga PF08280.6 AIO00523.1 - 0.29 10.9 0.0 0.7 9.6 0.0 1.6 1 0 0 1 1 1 0 M protein trans-acting positive regulator (MGA) HTH domain Kdo PF06293.9 AIO00523.1 - 0.38 9.7 0.0 0.74 8.8 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinesin PF00225.18 AIO00524.1 - 7.2e-81 271.4 0.0 7.2e-81 271.4 0.0 2.5 3 0 0 3 3 3 1 Kinesin motor domain ELM2 PF01448.19 AIO00524.1 - 2.6 8.7 6.3 12 6.6 1.0 3.7 3 0 0 3 3 3 0 ELM2 domain tRNA_m1G_MT PF01746.16 AIO00525.1 - 2e-25 89.4 0.0 4.8e-25 88.2 0.0 1.6 2 0 0 2 2 2 1 tRNA (Guanine-1)-methyltransferase GHMP_kinases_N PF00288.21 AIO00526.1 - 2.1e-09 37.2 0.6 5.3e-09 36.0 0.4 1.7 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 AIO00526.1 - 4.5e-07 29.9 0.1 1.1e-06 28.7 0.1 1.7 1 0 0 1 1 1 1 GHMP kinases C terminal PPR_3 PF13812.1 AIO00528.1 - 0.025 14.8 0.7 54 4.4 0.0 5.0 4 0 0 4 4 4 0 Pentatricopeptide repeat domain SAM_decarbox PF01536.11 AIO00529.1 - 5.1e-119 396.8 0.0 5.9e-119 396.6 0.0 1.0 1 0 0 1 1 1 1 Adenosylmethionine decarboxylase SAM_decarbox PF01536.11 AIO00530.1 - 3.5e-18 65.3 0.1 7e-14 51.2 0.0 2.0 2 0 0 2 2 2 2 Adenosylmethionine decarboxylase tRNA-synt_1 PF00133.17 AIO00531.1 - 8.1e-190 631.7 0.0 3.6e-189 629.6 0.0 1.8 1 1 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 AIO00531.1 - 5.7e-35 120.3 0.0 9.8e-35 119.5 0.0 1.4 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.6 AIO00531.1 - 2.3e-15 56.1 0.2 1e-07 31.0 0.0 3.9 3 1 0 3 3 3 3 tRNA synthetases class I (M) Val_tRNA-synt_C PF10458.4 AIO00531.1 - 2.9e-15 56.0 1.6 6.4e-15 54.9 1.1 1.6 1 0 0 1 1 1 1 Valyl tRNA synthetase tRNA binding arm tRNA-synt_1_2 PF13603.1 AIO00531.1 - 4.2e-08 32.7 0.0 0.00026 20.3 0.0 2.5 1 1 1 2 2 2 2 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1d PF00750.14 AIO00531.1 - 0.0097 14.7 0.0 0.63 8.7 0.0 2.5 3 0 0 3 3 3 1 tRNA synthetases class I (R) tRNA-synt_1e PF01406.14 AIO00531.1 - 0.015 14.4 0.1 1.4 7.9 0.0 3.2 4 0 0 4 4 4 0 tRNA synthetases class I (C) catalytic domain tRNA-synt_1b PF00579.20 AIO00531.1 - 0.043 12.9 0.1 0.11 11.5 0.0 1.6 2 0 0 2 2 2 0 tRNA synthetases class I (W and Y) Mnd1 PF03962.10 AIO00531.1 - 0.045 13.4 0.1 0.11 12.1 0.1 1.6 1 0 0 1 1 1 0 Mnd1 family tRNA-synt_1f PF01921.13 AIO00531.1 - 0.092 11.4 0.0 0.17 10.5 0.0 1.3 1 0 0 1 1 1 0 tRNA synthetases class I (K) Laminin_II PF06009.7 AIO00531.1 - 0.11 12.2 0.1 0.3 10.8 0.0 1.8 2 0 0 2 2 2 0 Laminin Domain II YvrJ PF12841.2 AIO00531.1 - 0.15 11.3 1.6 0.17 11.2 0.3 1.7 2 0 0 2 2 2 0 YvrJ protein family Sororin PF09666.5 AIO00532.1 - 0.0099 16.0 0.2 0.016 15.3 0.2 1.4 1 0 0 1 1 1 1 Sororin protein Retro_M PF02813.9 AIO00532.1 - 0.015 15.4 0.0 0.2 11.8 0.0 2.3 2 0 0 2 2 2 0 Retroviral M domain TRAP_beta PF05753.9 AIO00533.1 - 3.4e-17 62.1 2.0 1.1e-16 60.5 1.4 1.8 1 1 0 1 1 1 1 Translocon-associated protein beta (TRAPB) CARDB PF07705.6 AIO00533.1 - 2e-06 27.7 0.3 3.1e-06 27.1 0.2 1.2 1 0 0 1 1 1 1 CARDB DUF11 PF01345.13 AIO00533.1 - 5.3e-06 26.3 0.2 5.3e-06 26.3 0.2 2.4 2 1 1 3 3 3 1 Domain of unknown function DUF11 NPCBM_assoc PF10633.4 AIO00533.1 - 0.0052 16.7 0.2 0.022 14.7 0.1 2.0 1 1 0 1 1 1 1 NPCBM-associated, NEW3 domain of alpha-galactosidase Transglut_C PF00927.17 AIO00533.1 - 0.059 13.4 0.0 0.12 12.4 0.0 1.4 1 0 0 1 1 1 0 Transglutaminase family, C-terminal ig like domain Ank_2 PF12796.2 AIO00534.1 - 0.055 13.8 0.1 5.8 7.3 0.0 2.4 2 0 0 2 2 2 0 Ankyrin repeats (3 copies) Trichoplein PF13868.1 AIO00535.1 - 1.4e-54 184.8 131.1 1.4e-54 184.8 90.9 1.9 2 0 0 2 2 2 1 Tumour suppressor, Mitostatin TraU PF06834.6 AIO00535.1 - 0.64 9.0 2.0 1.1 8.3 1.4 1.3 1 0 0 1 1 1 0 TraU protein RRM_1 PF00076.17 AIO00536.1 - 3.3e-08 33.0 0.0 4.8e-08 32.5 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 AIO00536.1 - 2.7e-07 30.4 0.0 4.3e-07 29.8 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 AIO00536.1 - 3.8e-07 29.8 0.0 5.4e-07 29.3 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) HMG-CoA_red PF00368.13 AIO00537.1 - 1.5e-152 507.6 4.9 1.8e-152 507.3 3.4 1.0 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A reductase Ribosomal_S26e PF01283.14 AIO00538.1 - 2.3e-41 140.6 3.6 2.4e-41 140.5 2.5 1.0 1 0 0 1 1 1 1 Ribosomal protein S26e DUF2274 PF10038.4 AIO00539.1 - 0.053 13.6 0.2 0.21 11.7 0.1 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2274) tRNA-synt_1c PF00749.16 AIO00543.1 - 3.6e-101 337.9 0.0 5.2e-101 337.4 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.13 AIO00543.1 - 6.1e-35 120.4 0.1 1.4e-34 119.2 0.1 1.6 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain Helicase_C PF00271.26 AIO00544.1 - 1.1e-11 44.3 0.0 3.7e-11 42.7 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HA2 PF04408.18 AIO00544.1 - 1.1e-10 41.4 0.0 4.2e-10 39.5 0.0 2.0 1 0 0 1 1 1 1 Helicase associated domain (HA2) DEAD PF00270.24 AIO00544.1 - 1.4e-10 40.8 0.0 6.9e-10 38.6 0.0 2.1 1 1 0 1 1 1 1 DEAD/DEAH box helicase OB_NTP_bind PF07717.11 AIO00544.1 - 3.4e-07 30.0 0.0 9.5e-07 28.6 0.0 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold AAA_22 PF13401.1 AIO00544.1 - 5.6e-06 26.5 1.8 2.6e-05 24.3 0.0 2.9 3 0 0 3 3 3 1 AAA domain ResIII PF04851.10 AIO00544.1 - 0.0025 17.6 0.1 0.21 11.4 0.0 2.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit KaiC PF06745.8 AIO00544.1 - 0.1 11.6 2.7 0.13 11.3 0.0 2.4 3 0 0 3 3 3 0 KaiC DUF4250 PF14056.1 AIO00544.1 - 0.13 12.0 0.4 0.33 10.6 0.3 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4250) AAA_23 PF13476.1 AIO00544.1 - 8.4 6.6 9.3 4.8 7.4 0.0 2.6 2 0 0 2 2 2 0 AAA domain G-alpha PF00503.15 AIO00544.1 - 8.8 4.8 7.7 38 2.7 5.3 2.1 1 1 0 1 1 1 0 G-protein alpha subunit Ank_2 PF12796.2 AIO00545.1 - 6.2e-40 135.4 5.5 2.3e-19 69.5 0.1 4.3 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.25 AIO00545.1 - 4.5e-34 114.5 9.7 1.2e-06 27.9 0.0 7.5 7 0 0 7 7 7 6 Ankyrin repeat Ank_4 PF13637.1 AIO00545.1 - 5.9e-33 112.6 7.9 6.3e-10 39.3 0.1 6.8 2 2 5 7 7 7 6 Ankyrin repeats (many copies) Ank_5 PF13857.1 AIO00545.1 - 3.6e-28 96.9 12.9 8.2e-09 35.4 0.4 6.1 4 1 2 6 6 6 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 AIO00545.1 - 4.4e-26 88.3 5.1 0.00035 20.5 0.0 7.9 8 0 0 8 8 8 7 Ankyrin repeat Antifungal_pept PF11410.3 AIO00545.1 - 0.21 11.6 2.1 0.55 10.3 1.5 1.6 1 0 0 1 1 1 0 Antifungal peptide FlgN PF05130.7 AIO00545.1 - 0.89 9.7 5.2 4 7.6 0.1 3.0 3 0 0 3 3 3 0 FlgN protein Metallophos PF00149.23 AIO00547.1 - 9.4e-12 44.7 0.3 2.5e-11 43.3 0.2 1.7 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase XPC-binding PF09280.6 AIO00549.1 - 1.6e-11 43.4 0.2 3.1e-11 42.5 0.1 1.4 1 0 0 1 1 1 1 XPC-binding domain ubiquitin PF00240.18 AIO00549.1 - 1.8e-11 43.2 0.0 3.9e-11 42.1 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin family UBA PF00627.26 AIO00549.1 - 2.9e-07 30.1 3.2 2.3e-05 24.0 0.2 2.5 2 0 0 2 2 2 2 UBA/TS-N domain Rad60-SLD PF11976.3 AIO00549.1 - 1.3e-06 27.9 0.2 3.3e-06 26.7 0.1 1.7 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like YukD PF08817.5 AIO00549.1 - 0.0039 17.7 0.1 0.021 15.4 0.0 2.2 2 0 0 2 2 2 1 WXG100 protein secretion system (Wss), protein YukD UBA_3 PF09288.5 AIO00549.1 - 0.0045 16.5 0.0 0.025 14.1 0.0 2.1 2 0 0 2 2 2 1 Fungal ubiquitin-associated domain MCM_N PF14551.1 AIO00549.1 - 0.056 13.9 0.0 0.11 13.0 0.0 1.3 1 0 0 1 1 1 0 MCM N-terminal domain MORN PF02493.15 AIO00550.1 - 1.3e-94 304.6 108.0 2.5e-10 39.4 1.7 15.2 15 0 0 15 15 15 15 MORN repeat BAR PF03114.13 AIO00551.1 - 2.5e-05 23.8 1.8 3.5e-05 23.4 1.3 1.2 1 0 0 1 1 1 1 BAR domain Ribosomal_L6 PF00347.18 AIO00553.1 - 1.6e-26 92.6 2.1 7.6e-15 55.1 0.2 2.1 2 0 0 2 2 2 2 Ribosomal protein L6 Hormone_2 PF00123.15 AIO00553.1 - 0.046 13.5 0.0 30 4.5 0.0 3.1 3 0 0 3 3 3 0 Peptide hormone EF-hand_1 PF00036.27 AIO00555.1 - 1.8e-37 123.7 13.5 3.7e-05 22.7 0.0 10.8 11 0 0 11 11 11 8 EF hand EF-hand_7 PF13499.1 AIO00555.1 - 1.3e-35 121.3 20.8 7.7e-09 35.5 0.0 6.7 6 1 1 7 7 7 6 EF-hand domain pair EF-hand_5 PF13202.1 AIO00555.1 - 2.3e-32 108.8 7.7 4.8e-05 22.5 0.0 9.7 10 0 0 10 10 10 7 EF hand EF-hand_6 PF13405.1 AIO00555.1 - 4.5e-31 103.9 15.3 0.00038 20.0 0.0 10.5 10 0 0 10 10 10 6 EF-hand domain EF-hand_8 PF13833.1 AIO00555.1 - 2.2e-19 68.7 18.1 0.0014 18.1 0.0 10.1 7 4 3 10 10 10 6 EF-hand domain pair SPARC_Ca_bdg PF10591.4 AIO00555.1 - 1.2e-11 44.6 0.2 0.051 13.6 0.0 5.5 4 1 1 5 5 5 3 Secreted protein acidic and rich in cysteine Ca binding region Caleosin PF05042.8 AIO00555.1 - 0.0066 16.0 0.1 2.6 7.5 0.0 3.8 4 0 0 4 4 4 1 Caleosin related protein SHOCT PF09851.4 AIO00555.1 - 0.052 13.0 0.2 10 5.7 0.0 3.6 3 0 0 3 3 3 0 Short C-terminal domain EF-hand_10 PF14788.1 AIO00555.1 - 0.093 12.4 0.0 24 4.6 0.0 4.4 5 0 0 5 5 5 0 EF hand LXG PF04740.7 AIO00555.1 - 0.17 11.6 1.2 0.54 10.0 0.1 2.0 2 0 0 2 2 2 0 LXG domain of WXG superfamily Excalibur PF05901.6 AIO00555.1 - 0.2 12.0 1.8 37 4.7 0.1 4.2 4 0 0 4 4 4 0 Excalibur calcium-binding domain DUF4484 PF14831.1 AIO00555.1 - 3.7 7.6 7.2 0.3 11.1 0.9 2.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4484) PGK PF00162.14 AIO00557.1 - 3.5e-138 460.3 0.1 4.4e-138 460.0 0.0 1.1 1 0 0 1 1 1 1 Phosphoglycerate kinase PAS PF00989.19 AIO00557.1 - 4.5e-07 29.6 0.0 1.6e-06 27.8 0.0 1.9 2 0 0 2 2 2 1 PAS fold PAS_9 PF13426.1 AIO00557.1 - 1.2e-05 25.6 0.0 3.8e-05 24.0 0.0 1.9 1 0 0 1 1 1 1 PAS domain PAS_4 PF08448.5 AIO00557.1 - 2.4e-05 24.3 0.0 7.1e-05 22.8 0.0 1.8 2 0 0 2 2 2 1 PAS fold PAS_8 PF13188.1 AIO00557.1 - 0.0017 18.1 0.0 0.0064 16.3 0.0 2.0 1 0 0 1 1 1 1 PAS domain SpoVS PF04232.7 AIO00557.1 - 0.039 13.5 0.4 0.21 11.1 0.0 2.4 2 1 0 2 2 2 0 Stage V sporulation protein S (SpoVS) CAS_CSE1 PF03378.10 AIO00558.1 - 4.5e-63 213.0 0.0 9.7e-63 211.9 0.0 1.6 1 0 0 1 1 1 1 CAS/CSE protein, C-terminus Cse1 PF08506.5 AIO00558.1 - 5e-47 160.2 0.0 6.9e-47 159.7 0.0 1.2 1 0 0 1 1 1 1 Cse1 IBN_N PF03810.14 AIO00558.1 - 0.0035 17.2 0.0 0.026 14.4 0.0 2.5 3 0 0 3 3 3 1 Importin-beta N-terminal domain Xpo1 PF08389.7 AIO00558.1 - 0.0074 16.2 1.5 2.4 8.0 0.2 4.0 3 1 1 4 4 4 1 Exportin 1-like protein DUF3753 PF12575.3 AIO00558.1 - 0.11 12.3 1.0 10 6.0 0.1 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3753) MCM_N PF14551.1 AIO00558.1 - 0.11 13.0 0.0 4.2 7.8 0.0 3.0 3 0 0 3 3 3 0 MCM N-terminal domain WD40 PF00400.27 AIO00560.1 - 4.2e-10 39.1 10.0 0.0029 17.4 0.4 4.8 4 0 0 4 4 4 3 WD domain, G-beta repeat Dynein_heavy PF03028.10 AIO00560.1 - 0.032 12.2 0.0 0.045 11.7 0.0 1.1 1 0 0 1 1 1 0 Dynein heavy chain and region D6 of dynein motor Tcp11 PF05794.8 AIO00561.1 - 5.6e-24 84.6 0.7 2.8e-23 82.3 0.5 1.9 1 1 0 1 1 1 1 T-complex protein 11 DUF469 PF04320.9 AIO00561.1 - 0.1 13.3 0.1 0.29 11.9 0.0 1.7 1 0 0 1 1 1 0 Protein with unknown function (DUF469) MKT1_C PF12246.3 AIO00562.1 - 1.3e-27 96.3 0.0 1.7e-27 95.9 0.0 1.2 1 0 0 1 1 1 1 Temperature dependent protein affecting M2 dsRNA replication MKT1_N PF12247.3 AIO00562.1 - 4.2e-17 62.2 0.0 8.4e-17 61.2 0.0 1.5 1 0 0 1 1 1 1 Temperature dependent protein affecting M2 dsRNA replication DNA_ligase_A_M PF01068.16 AIO00563.1 - 4.6e-52 176.3 0.0 7.1e-52 175.7 0.0 1.3 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.9 AIO00563.1 - 1.1e-38 132.7 0.0 1.8e-38 132.1 0.0 1.3 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_C PF04679.10 AIO00563.1 - 1e-25 89.9 0.2 1.2e-24 86.4 0.0 2.5 2 0 0 2 2 2 1 ATP dependent DNA ligase C terminal region DNA_ligase_OB_2 PF14743.1 AIO00563.1 - 0.054 13.1 0.9 0.71 9.5 0.0 2.6 2 0 0 2 2 2 0 DNA ligase OB-like domain TPR_11 PF13414.1 AIO00565.1 - 2.5e-14 52.6 4.8 8e-05 22.2 0.1 4.1 3 1 0 4 4 4 4 TPR repeat TPR_16 PF13432.1 AIO00565.1 - 2.5e-10 40.7 1.5 3.8e-05 24.2 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.1 AIO00565.1 - 4.9e-08 32.9 4.1 0.083 13.5 0.0 4.7 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_17 PF13431.1 AIO00565.1 - 8.5e-08 31.8 0.4 1.7 9.0 0.0 4.4 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.12 AIO00565.1 - 5.1e-06 26.0 3.6 0.0097 15.7 0.0 4.4 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_1 PF00515.23 AIO00565.1 - 8.4e-05 22.0 0.2 9.4 6.0 0.0 4.1 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_9 PF13371.1 AIO00565.1 - 0.00012 21.8 6.0 0.0039 17.0 0.2 3.5 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.1 AIO00565.1 - 0.0004 20.6 3.2 0.043 14.1 0.1 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat SPO22 PF08631.5 AIO00565.1 - 0.00075 18.6 0.0 0.59 9.1 0.0 2.3 2 0 0 2 2 2 2 Meiosis protein SPO22/ZIP4 like Apc3 PF12895.2 AIO00565.1 - 0.034 14.2 0.5 0.1 12.7 0.1 2.0 2 0 0 2 2 1 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_15 PF13429.1 AIO00565.1 - 0.038 13.0 0.5 0.18 10.8 0.0 2.2 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_8 PF13181.1 AIO00565.1 - 0.077 12.8 0.2 38 4.3 0.0 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat ChAPs PF09295.5 AIO00565.1 - 0.079 11.7 0.1 0.1 11.3 0.1 1.1 1 0 0 1 1 1 0 ChAPs (Chs5p-Arf1p-binding proteins) ASXH PF13919.1 AIO00565.1 - 0.12 12.1 0.1 0.25 11.1 0.1 1.5 1 0 0 1 1 1 0 Asx homology domain Yippee-Mis18 PF03226.9 AIO00566.1 - 6.6e-14 51.7 0.3 8.2e-14 51.4 0.2 1.1 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly C1_4 PF07975.7 AIO00566.1 - 0.0046 16.9 1.1 0.83 9.6 0.0 2.3 2 0 0 2 2 2 2 TFIIH C1-like domain Endonuclease_7 PF02945.10 AIO00566.1 - 0.23 11.2 1.3 0.58 9.8 0.9 1.9 1 1 0 1 1 1 0 Recombination endonuclease VII RIG-I_C-RD PF11648.3 AIO00566.1 - 0.26 11.1 1.9 0.66 9.8 1.3 1.6 1 1 0 1 1 1 0 C-terminal domain of RIG-I zf-AN1 PF01428.11 AIO00566.1 - 1.5 8.7 4.9 0.72 9.7 0.5 2.3 3 0 0 3 3 3 0 AN1-like Zinc finger Pkinase PF00069.20 AIO00567.1 - 8.4e-30 103.7 0.0 1e-29 103.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AIO00567.1 - 2.4e-12 46.4 0.0 2.8e-12 46.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 AIO00567.1 - 0.14 11.8 0.0 0.25 11.0 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pneumo_att_G PF05539.6 AIO00568.1 - 2 7.7 6.6 2.7 7.2 4.6 1.2 1 0 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G zf-MIZ PF02891.15 AIO00569.1 - 7.7e-18 63.7 5.6 1.3e-17 63.0 3.8 1.4 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger zf-Nse PF11789.3 AIO00569.1 - 1.1e-06 28.0 1.3 2.1e-06 27.1 0.9 1.5 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit Rtf2 PF04641.7 AIO00569.1 - 0.066 12.4 0.6 0.11 11.7 0.4 1.2 1 0 0 1 1 1 0 Rtf2 RING-finger zf-C3HC4_4 PF15227.1 AIO00569.1 - 0.41 10.5 5.8 0.77 9.6 4.0 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING S-AdoMet_synt_C PF02773.11 AIO00570.1 - 1.9e-68 228.4 0.2 3.1e-68 227.7 0.2 1.3 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, C-terminal domain S-AdoMet_synt_M PF02772.11 AIO00570.1 - 1.8e-44 150.5 0.0 2.2e-43 147.0 0.0 2.1 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, central domain S-AdoMet_synt_N PF00438.15 AIO00570.1 - 4.3e-40 135.9 0.3 7.9e-40 135.1 0.2 1.5 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, N-terminal domain Strep_pep PF14404.1 AIO00570.1 - 0.03 14.5 0.0 0.081 13.1 0.0 1.7 1 0 0 1 1 1 0 Ribosomally synthesized peptide in Streptomyces species Rhodanese PF00581.15 AIO00571.1 - 1.4e-05 25.3 0.0 2.2e-05 24.7 0.0 1.3 1 0 0 1 1 1 1 Rhodanese-like domain RF-1 PF00472.15 AIO00572.1 - 2.9e-11 43.1 0.0 7.6e-11 41.8 0.0 1.8 1 0 0 1 1 1 1 RF-1 domain Caldesmon PF02029.10 AIO00572.1 - 0.005 15.3 0.4 0.0088 14.5 0.3 1.3 1 0 0 1 1 1 1 Caldesmon MgtE_N PF03448.12 AIO00572.1 - 0.1 12.9 0.8 0.24 11.7 0.6 1.6 1 0 0 1 1 1 0 MgtE intracellular N domain p450 PF00067.17 AIO00573.1 - 1.2e-48 165.8 0.0 1.6e-48 165.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Mago_nashi PF02792.9 AIO00574.1 - 3.2e-54 182.5 0.1 3.7e-54 182.3 0.1 1.0 1 0 0 1 1 1 1 Mago nashi protein zf-CCCH PF00642.19 AIO00575.1 - 3.1e-06 26.7 2.1 7.3e-06 25.5 1.5 1.7 1 1 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Pkinase PF00069.20 AIO00576.1 - 9e-36 123.3 0.1 7.5e-17 61.3 0.0 2.5 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 AIO00576.1 - 8.5e-10 38.1 0.0 8.3e-05 21.7 0.0 2.4 2 0 0 2 2 2 2 Protein tyrosine kinase Ribosomal_S11 PF00411.14 AIO00577.1 - 3.2e-41 139.9 0.5 3.9e-41 139.6 0.4 1.1 1 0 0 1 1 1 1 Ribosomal protein S11 DUF814 PF05670.8 AIO00577.1 - 0.04 13.8 0.0 0.054 13.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF814) DUF2252 PF10009.4 AIO00577.1 - 0.12 11.2 0.0 0.15 10.8 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2252) ATP-synt_DE_N PF02823.11 AIO00578.1 - 7.6e-16 57.6 0.0 1.1e-15 57.0 0.0 1.3 1 0 0 1 1 1 1 ATP synthase, Delta/Epsilon chain, beta-sandwich domain L27_1 PF09058.5 AIO00578.1 - 0.023 14.5 0.2 0.049 13.5 0.1 1.5 1 0 0 1 1 1 0 L27_1 ATP-synt_DE PF00401.15 AIO00578.1 - 0.24 11.2 3.8 0.36 10.7 2.6 1.3 1 0 0 1 1 1 0 ATP synthase, Delta/Epsilon chain, long alpha-helix domain DUF773 PF05600.7 AIO00579.1 - 8e-12 44.6 14.8 2.8e-06 26.3 0.4 4.0 2 2 2 4 4 4 4 Protein of unknown function (DUF773) CENP-F_leu_zip PF10473.4 AIO00579.1 - 0.22 11.4 7.9 0.058 13.2 2.3 2.3 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Prefoldin_2 PF01920.15 AIO00579.1 - 0.93 9.2 4.4 1.6 8.5 0.1 2.9 2 2 2 4 4 4 0 Prefoldin subunit FlgN PF05130.7 AIO00579.1 - 1.2 9.3 7.2 1.2 9.3 0.8 2.8 2 1 1 3 3 3 0 FlgN protein Cyclin PF08613.6 AIO00581.1 - 1.4e-20 74.2 0.1 2.2e-20 73.5 0.1 1.3 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.18 AIO00581.1 - 5.7e-08 32.3 0.1 9.1e-08 31.7 0.1 1.2 1 0 0 1 1 1 1 Cyclin, N-terminal domain zinc_ribbon_2 PF13240.1 AIO00581.1 - 0.11 12.0 0.2 0.24 10.9 0.1 1.6 1 0 0 1 1 1 0 zinc-ribbon domain LRR_4 PF12799.2 AIO00582.1 - 1.2e-17 63.1 13.3 3.1e-06 26.6 0.2 3.6 3 0 0 3 3 3 3 Leucine Rich repeats (2 copies) LRR_9 PF14580.1 AIO00582.1 - 1.5e-13 50.6 1.4 3.3e-08 33.2 0.1 2.6 1 1 1 2 2 2 2 Leucine-rich repeat LRR_8 PF13855.1 AIO00582.1 - 3.6e-10 39.4 18.6 1.6e-07 30.9 3.5 3.3 1 1 2 3 3 3 3 Leucine rich repeat LRR_1 PF00560.28 AIO00582.1 - 0.0095 15.8 14.9 1.9 8.8 0.7 5.4 4 1 0 4 4 4 2 Leucine Rich Repeat LRR_6 PF13516.1 AIO00582.1 - 0.032 14.3 13.9 0.3 11.2 0.0 4.8 2 1 3 5 5 5 0 Leucine Rich repeat LRR_7 PF13504.1 AIO00582.1 - 0.032 14.3 13.9 10 6.8 0.1 5.7 3 1 0 3 3 3 0 Leucine rich repeat Ribosomal_L15e PF00827.12 AIO00583.1 - 6.7e-90 299.7 9.9 7.6e-90 299.5 6.8 1.0 1 0 0 1 1 1 1 Ribosomal L15 ATP-synt_C PF00137.16 AIO00584.1 - 9e-27 92.7 39.6 1.8e-15 56.5 8.4 2.7 3 0 0 3 3 3 2 ATP synthase subunit C SnoaL_2 PF12680.2 AIO00585.1 - 2.3e-05 24.7 0.0 3.3e-05 24.2 0.0 1.5 1 1 0 1 1 1 1 SnoaL-like domain SnoaL_3 PF13474.1 AIO00585.1 - 0.00013 21.9 0.1 0.00029 20.8 0.1 1.6 1 1 0 1 1 1 1 SnoaL-like domain SnoaL PF07366.7 AIO00585.1 - 0.0031 17.0 0.0 0.0042 16.6 0.0 1.4 1 0 0 1 1 1 1 SnoaL-like polyketide cyclase DUF4440 PF14534.1 AIO00585.1 - 0.0068 16.5 0.0 0.018 15.2 0.0 1.7 1 1 1 2 2 2 1 Domain of unknown function (DUF4440) DUF3808 PF10300.4 AIO00587.1 - 3.2e-29 101.8 6.1 5e-28 97.8 3.3 2.9 2 1 0 2 2 2 1 Protein of unknown function (DUF3808) TPR_12 PF13424.1 AIO00587.1 - 1.5e-12 47.2 0.2 8.6e-06 25.6 0.1 3.4 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_11 PF13414.1 AIO00587.1 - 1.1e-09 37.7 7.9 0.0012 18.3 0.1 4.5 5 0 0 5 5 5 2 TPR repeat TPR_2 PF07719.12 AIO00587.1 - 1.5e-07 30.8 1.0 0.049 13.5 0.0 4.2 4 0 0 4 4 4 2 Tetratricopeptide repeat Apc3 PF12895.2 AIO00587.1 - 3.8e-05 23.7 2.9 0.007 16.4 0.2 3.9 4 0 0 4 4 4 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.1 AIO00587.1 - 0.00011 22.4 0.5 10 6.5 0.1 5.4 4 2 1 5 5 5 2 Tetratricopeptide repeat TPR_16 PF13432.1 AIO00587.1 - 0.00054 20.5 0.1 4.1 8.1 0.1 4.4 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_6 PF13174.1 AIO00587.1 - 0.0036 17.6 7.7 4.4 7.9 0.3 5.2 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_1 PF00515.23 AIO00587.1 - 0.0061 16.1 1.3 2.3 7.9 0.0 3.8 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_8 PF13181.1 AIO00587.1 - 0.036 13.8 7.7 0.8 9.6 0.1 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF2225 PF09986.4 AIO00587.1 - 0.043 13.2 5.4 0.12 11.8 0.9 2.9 2 1 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2225) CPSF_A PF03178.10 AIO00589.1 - 8.1e-58 196.0 0.0 1.4e-57 195.2 0.0 1.3 1 0 0 1 1 1 1 CPSF A subunit region MMS1_N PF10433.4 AIO00589.1 - 0.014 13.5 0.0 0.025 12.7 0.0 1.3 1 0 0 1 1 1 0 Mono-functional DNA-alkylating methyl methanesulfonate N-term Ribosomal_60s PF00428.14 AIO00590.1 - 9.8e-23 80.3 7.8 1.1e-22 80.1 5.4 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein PepSY_2 PF13670.1 AIO00590.1 - 0.45 10.4 7.8 11 6.0 0.0 2.2 2 0 0 2 2 2 0 Peptidase propeptide and YPEB domain Ribosomal_60s PF00428.14 AIO00591.1 - 9.8e-23 80.3 7.8 1.1e-22 80.1 5.4 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein PepSY_2 PF13670.1 AIO00591.1 - 0.45 10.4 7.8 11 6.0 0.0 2.2 2 0 0 2 2 2 0 Peptidase propeptide and YPEB domain Meth_synt_2 PF01717.13 AIO00593.1 - 1e-143 478.2 0.0 1.1e-134 448.5 0.0 2.2 2 0 0 2 2 2 2 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.7 AIO00593.1 - 5e-127 423.4 0.0 1e-112 376.4 0.0 3.1 3 0 0 3 3 3 3 Cobalamin-independent synthase, N-terminal domain MIP PF00230.15 AIO00594.1 - 1.6e-51 174.9 11.0 1.9e-51 174.7 7.6 1.0 1 0 0 1 1 1 1 Major intrinsic protein DUF4407 PF14362.1 AIO00594.1 - 1.1 8.1 0.0 1.1 8.1 0.0 2.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4407) RINGv PF12906.2 AIO00595.1 - 1.8e-11 43.8 5.4 1.8e-11 43.8 3.7 2.1 2 0 0 2 2 2 1 RING-variant domain DUF4587 PF15248.1 AIO00595.1 - 0.089 13.3 2.0 0.27 11.8 1.4 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4587) DUF4529 PF15032.1 AIO00595.1 - 0.45 9.0 0.1 0.79 8.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4529) MFS_2 PF13347.1 AIO00596.1 - 3e-07 29.1 14.8 3e-07 29.1 10.3 2.3 1 1 1 2 2 2 1 MFS/sugar transport protein BT1 PF03092.11 AIO00596.1 - 1.8e-06 26.9 17.0 2.1e-05 23.4 11.8 2.0 1 1 0 1 1 1 1 BT1 family CYSTM PF12734.2 AIO00596.1 - 0.27 11.3 2.6 1.8 8.7 0.7 2.8 2 0 0 2 2 2 0 Cysteine-rich TM module stress tolerance Pro_isomerase PF00160.16 AIO00597.1 - 9.1e-44 149.3 0.0 1.1e-43 149.1 0.0 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD ResIII PF04851.10 AIO00599.1 - 1.1e-13 51.4 0.0 1.8e-12 47.4 0.0 2.2 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.24 AIO00599.1 - 2.6e-09 36.8 0.0 4.5e-09 36.0 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase T5orf172 PF10544.4 AIO00599.1 - 8.3e-09 35.7 0.0 2e-08 34.5 0.0 1.6 1 0 0 1 1 1 1 T5orf172 domain Helicase_C PF00271.26 AIO00599.1 - 2.5e-05 24.0 0.0 6.2e-05 22.7 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain MUG113 PF13455.1 AIO00599.1 - 0.0041 17.5 0.1 0.013 15.9 0.0 1.9 1 0 0 1 1 1 1 Meiotically up-regulated gene 113 DUF3505 PF12013.3 AIO00599.1 - 0.016 15.4 0.5 0.071 13.3 0.3 2.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3505) zf-CCCH PF00642.19 AIO00600.1 - 0.0041 16.7 12.4 0.013 15.1 3.5 2.5 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.1 AIO00600.1 - 1.2 9.2 10.5 0.7 9.9 3.5 2.3 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type Peptidase_M22 PF00814.20 AIO00602.1 - 2.9e-84 282.7 0.0 3.4e-84 282.4 0.0 1.0 1 0 0 1 1 1 1 Glycoprotease family FG-GAP PF01839.18 AIO00603.1 - 8.5e-15 53.9 25.8 0.013 15.1 0.0 7.1 7 0 0 7 7 7 5 FG-GAP repeat VCBS PF13517.1 AIO00603.1 - 5.7e-11 42.6 17.7 0.00071 19.8 3.7 6.5 5 2 3 8 8 8 6 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella PQQ_2 PF13360.1 AIO00603.1 - 1.4e-06 28.0 0.3 0.0066 15.9 0.1 2.7 1 1 1 2 2 2 2 PQQ-like domain BBS2_C PF14782.1 AIO00603.1 - 0.014 13.9 0.1 1.1 7.6 0.0 2.9 3 0 0 3 3 3 0 Ciliary BBSome complex subunit 2, C-terminal TcdB_toxin_midN PF12256.3 AIO00603.1 - 0.017 14.5 8.1 0.34 10.3 0.6 3.8 3 1 1 4 4 4 0 Insecticide toxin TcdB middle/N-terminal region PQQ_3 PF13570.1 AIO00603.1 - 0.76 10.1 19.5 11 6.4 0.1 6.6 6 1 0 6 6 6 0 PQQ-like domain Filament PF00038.16 AIO00605.1 - 0.15 11.5 70.4 0.063 12.7 20.0 3.8 1 1 2 3 3 3 0 Intermediate filament protein UCH PF00443.24 AIO00606.1 - 4.1e-44 150.7 0.0 5.9e-44 150.1 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 AIO00606.1 - 3.6e-16 59.4 0.0 5.3e-16 58.9 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase ubiquitin PF00240.18 AIO00606.1 - 4.2e-09 35.6 0.0 1.1e-08 34.3 0.0 1.7 1 0 0 1 1 1 1 Ubiquitin family Ubiquitin_2 PF14560.1 AIO00606.1 - 0.019 15.2 0.0 0.049 13.8 0.0 1.7 1 0 0 1 1 1 0 Ubiquitin-like domain Milton PF12448.3 AIO00606.1 - 0.031 14.4 0.1 0.058 13.5 0.1 1.4 1 0 0 1 1 1 0 Kinesin associated protein Peptidase_C98 PF15499.1 AIO00606.1 - 0.15 11.3 0.0 17 4.5 0.0 2.2 2 0 0 2 2 2 0 Ubiquitin-specific peptidase-like, SUMO isopeptidase EPO_TPO PF00758.13 AIO00607.1 - 0.051 13.2 0.1 0.13 11.9 0.1 1.6 2 0 0 2 2 2 0 Erythropoietin/thrombopoietin RNA_pol_Rpb2_6 PF00562.23 AIO00608.1 - 9e-118 393.3 0.0 1.2e-117 392.9 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.10 AIO00608.1 - 1.1e-38 132.2 0.0 1.7e-38 131.6 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_7 PF04560.15 AIO00608.1 - 1e-28 99.3 0.0 6.6e-28 96.7 0.0 2.2 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_2 PF04561.9 AIO00608.1 - 7.8e-24 84.1 0.0 1.4e-23 83.2 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_4 PF04566.8 AIO00608.1 - 1.6e-23 82.2 2.9 3.2e-23 81.2 2.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_3 PF04565.11 AIO00608.1 - 8.8e-20 70.2 2.5 1.6e-19 69.4 0.1 2.4 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_5 PF04567.12 AIO00608.1 - 6.4e-09 35.6 0.8 1.3e-08 34.6 0.5 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 Zn_Tnp_IS1595 PF12760.2 AIO00608.1 - 0.16 11.7 2.8 0.5 10.2 2.0 1.9 1 0 0 1 1 1 0 Transposase zinc-ribbon domain Myb_DNA-binding PF00249.26 AIO00610.1 - 0.0095 15.9 0.0 0.65 10.0 0.0 2.2 2 0 0 2 2 2 2 Myb-like DNA-binding domain Nol1_Nop2_Fmu PF01189.12 AIO00611.1 - 1.5e-82 277.2 0.0 2e-82 276.7 0.0 1.2 1 0 0 1 1 1 1 NOL1/NOP2/sun family FtsJ PF01728.14 AIO00611.1 - 0.00056 19.9 0.0 0.0018 18.2 0.0 1.9 2 0 0 2 2 2 1 FtsJ-like methyltransferase Methyltransf_26 PF13659.1 AIO00611.1 - 0.00066 19.6 0.0 0.0024 17.9 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 AIO00611.1 - 0.019 14.5 0.0 0.034 13.7 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain PCMT PF01135.14 AIO00611.1 - 0.032 13.7 0.0 0.053 13.0 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) WD40 PF00400.27 AIO00612.1 - 8.7e-31 104.6 6.9 1.4e-07 31.0 0.0 7.4 7 0 0 7 7 7 7 WD domain, G-beta repeat NLE PF08154.7 AIO00612.1 - 1.6e-13 50.4 0.1 2.8e-13 49.6 0.1 1.4 1 0 0 1 1 1 1 NLE (NUC135) domain Lactonase PF10282.4 AIO00612.1 - 0.077 12.0 0.0 0.15 11.0 0.0 1.4 1 0 0 1 1 1 0 Lactonase, 7-bladed beta-propeller TFIIF_alpha PF05793.7 AIO00614.1 - 0.0062 14.9 15.5 0.0069 14.8 10.7 1.1 1 0 0 1 1 1 1 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Nop14 PF04147.7 AIO00614.1 - 0.0079 14.1 19.9 0.0079 14.1 13.8 1.1 1 0 0 1 1 1 1 Nop14-like family Daxx PF03344.10 AIO00614.1 - 0.03 12.8 16.6 0.034 12.6 11.5 1.1 1 0 0 1 1 1 0 Daxx Family CDC45 PF02724.9 AIO00614.1 - 0.057 11.4 12.8 0.065 11.2 8.8 1.2 1 0 0 1 1 1 0 CDC45-like protein Spore_coat_CotO PF14153.1 AIO00614.1 - 0.094 12.1 4.6 0.1 12.0 3.2 1.2 1 0 0 1 1 1 0 Spore coat protein CotO Vfa1 PF08432.5 AIO00614.1 - 0.12 12.4 5.4 0.15 12.0 3.7 1.3 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 SAPS PF04499.10 AIO00614.1 - 0.28 9.7 6.3 0.28 9.7 4.3 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein BUD22 PF09073.5 AIO00614.1 - 0.55 9.2 18.1 0.85 8.6 12.5 1.3 1 0 0 1 1 1 0 BUD22 Hid1 PF12722.2 AIO00614.1 - 1.3 6.5 3.5 1.4 6.4 2.4 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF2151 PF10221.4 AIO00614.1 - 1.7 6.7 5.1 1.7 6.7 3.5 1.1 1 0 0 1 1 1 0 Cell cycle and development regulator NOA36 PF06524.7 AIO00614.1 - 3.4 6.8 21.6 4.5 6.4 15.0 1.1 1 0 0 1 1 1 0 NOA36 protein Ebola_NP PF05505.7 AIO00614.1 - 3.5 5.5 10.3 3.8 5.4 7.1 1.1 1 0 0 1 1 1 0 Ebola nucleoprotein RR_TM4-6 PF06459.7 AIO00614.1 - 7.1 6.4 8.6 10 5.9 6.0 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 CDC27 PF09507.5 AIO00614.1 - 7.9 5.5 15.3 10 5.2 10.6 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 TPR_MLP1_2 PF07926.7 AIO00615.1 - 0.0068 16.1 21.2 0.0068 16.1 14.7 9.2 2 2 6 8 8 8 2 TPR/MLP1/MLP2-like protein Reo_sigmaC PF04582.7 AIO00615.1 - 2.2 7.4 33.7 0.3 10.2 1.1 6.2 1 1 5 7 7 7 0 Reovirus sigma C capsid protein Cupin_4 PF08007.7 AIO00616.1 - 2.2e-41 142.1 0.2 4.4e-41 141.1 0.1 1.4 1 1 0 1 1 1 1 Cupin superfamily protein Cupin_8 PF13621.1 AIO00616.1 - 1.2e-08 34.7 0.1 4.2e-08 33.0 0.1 2.0 1 1 0 1 1 1 1 Cupin-like domain Cupin_2 PF07883.6 AIO00616.1 - 0.026 14.0 0.0 0.069 12.6 0.0 1.7 1 0 0 1 1 1 0 Cupin domain JmjC PF02373.17 AIO00616.1 - 0.027 14.7 0.0 0.07 13.3 0.0 1.8 1 0 0 1 1 1 0 JmjC domain, hydroxylase 2OG-FeII_Oxy PF03171.15 AIO00616.1 - 0.033 14.4 0.1 0.084 13.1 0.1 1.7 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily Tetraspannin PF00335.15 AIO00616.1 - 0.16 11.2 0.0 0.3 10.3 0.0 1.4 1 0 0 1 1 1 0 Tetraspanin family Helicase_C PF00271.26 AIO00617.1 - 3.4e-09 36.4 0.0 1e-08 34.9 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 AIO00617.1 - 1.7e-07 30.9 0.0 5.1e-07 29.3 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase HA2 PF04408.18 AIO00617.1 - 0.0052 16.7 0.2 0.026 14.5 0.0 2.3 2 0 0 2 2 2 1 Helicase associated domain (HA2) DUF4559 PF15112.1 AIO00617.1 - 0.2 10.8 1.9 0.4 9.8 1.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4559) COPIIcoated_ERV PF07970.7 AIO00618.1 - 2.4e-20 73.1 0.0 3.6e-20 72.5 0.0 1.2 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.1 AIO00618.1 - 9e-07 28.7 0.0 1.7e-06 27.9 0.0 1.4 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) Kinesin PF00225.18 AIO00619.1 - 2.2e-87 292.9 0.0 3.1e-87 292.4 0.0 1.2 1 0 0 1 1 1 1 Kinesin motor domain DUF3972 PF13118.1 AIO00619.1 - 0.16 12.0 0.1 0.44 10.6 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3972) CRAL_TRIO PF00650.15 AIO00620.1 - 3.2e-11 42.9 0.0 5.7e-11 42.1 0.0 1.4 1 0 0 1 1 1 1 CRAL/TRIO domain Abhydrolase_6 PF12697.2 AIO00620.1 - 0.081 12.7 0.1 0.17 11.7 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family CRAL_TRIO PF00650.15 AIO00621.1 - 8.1e-14 51.4 0.0 1.4e-13 50.6 0.0 1.4 1 0 0 1 1 1 1 CRAL/TRIO domain Aa_trans PF01490.13 AIO00622.1 - 2e-43 148.4 35.0 2.4e-43 148.1 24.3 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.8 AIO00622.1 - 2e-10 40.0 20.9 5.1e-10 38.7 14.5 1.6 1 0 0 1 1 1 1 Tryptophan/tyrosine permease family AA_permease_2 PF13520.1 AIO00622.1 - 3.9e-09 35.5 25.4 3.9e-09 35.5 17.6 2.0 2 0 0 2 2 2 1 Amino acid permease HXXEE PF13787.1 AIO00622.1 - 0.032 14.6 0.6 0.032 14.6 0.4 3.3 3 1 0 3 3 3 0 Protein of unknown function with HXXEE motif BNIP2 PF12496.3 AIO00622.1 - 0.082 13.0 0.8 0.13 12.4 0.5 1.2 1 0 0 1 1 1 0 Bcl2-/adenovirus E1B nineteen kDa-interacting protein 2 Aa_trans PF01490.13 AIO00623.1 - 1.1e-50 172.3 28.0 1.3e-50 172.0 19.4 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.8 AIO00623.1 - 1.3e-07 30.8 10.5 1.3e-07 30.8 7.3 2.1 2 0 0 2 2 2 1 Tryptophan/tyrosine permease family Aa_trans PF01490.13 AIO00624.1 - 1e-48 165.8 34.0 1.2e-48 165.6 23.5 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein AA_permease_2 PF13520.1 AIO00624.1 - 1.4e-07 30.3 20.7 1.4e-07 30.3 14.3 2.0 2 0 0 2 2 2 1 Amino acid permease Trp_Tyr_perm PF03222.8 AIO00624.1 - 1e-06 27.8 19.1 1e-06 27.8 13.2 2.2 1 1 1 2 2 2 1 Tryptophan/tyrosine permease family CRAL_TRIO PF00650.15 AIO00625.1 - 6.3e-13 48.5 0.0 1.1e-12 47.6 0.0 1.4 1 0 0 1 1 1 1 CRAL/TRIO domain Peptidase_C2 PF00648.16 AIO00628.1 - 5.1e-38 130.7 0.0 7.2e-38 130.2 0.0 1.2 1 0 0 1 1 1 1 Calpain family cysteine protease DUF1935 PF09149.5 AIO00628.1 - 4e-26 90.9 0.0 7.2e-26 90.1 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1935) Peptidase_C2 PF00648.16 AIO00629.1 - 1.3e-22 80.1 0.0 2.5e-22 79.2 0.0 1.4 1 0 0 1 1 1 1 Calpain family cysteine protease DUF1935 PF09149.5 AIO00629.1 - 3.2e-15 55.9 0.1 1.8e-14 53.5 0.0 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF1935) DUF1935 PF09149.5 AIO00630.1 - 2.1e-19 69.4 0.0 4.6e-19 68.3 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1935) Peptidase_C2 PF00648.16 AIO00630.1 - 2.2e-12 46.6 0.0 3.6e-12 45.8 0.0 1.3 1 0 0 1 1 1 1 Calpain family cysteine protease Peptidase_C2 PF00648.16 AIO00631.1 - 2.3e-30 105.6 0.0 3.3e-30 105.1 0.0 1.2 1 0 0 1 1 1 1 Calpain family cysteine protease DUF1935 PF09149.5 AIO00631.1 - 1.3e-22 79.6 0.1 2.4e-22 78.8 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1935) PGA2 PF07543.7 AIO00631.1 - 0.071 12.9 0.1 0.12 12.1 0.0 1.3 1 0 0 1 1 1 0 Protein trafficking PGA2 TMCO5 PF14992.1 AIO00631.1 - 0.21 10.6 0.1 0.6 9.1 0.1 1.6 2 0 0 2 2 2 0 TMCO5 family Peptidase_C2 PF00648.16 AIO00632.1 - 5.1e-44 150.4 0.1 7.8e-44 149.8 0.0 1.3 1 0 0 1 1 1 1 Calpain family cysteine protease DUF1935 PF09149.5 AIO00632.1 - 1.3e-15 57.1 0.0 3.2e-15 55.9 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1935) RRF PF01765.14 AIO00632.1 - 0.011 15.2 0.0 0.018 14.5 0.0 1.2 1 0 0 1 1 1 0 Ribosome recycling factor Peptidase_C2 PF00648.16 AIO00633.1 - 2.1e-59 200.9 0.1 2.8e-59 200.5 0.1 1.1 1 0 0 1 1 1 1 Calpain family cysteine protease DUF1935 PF09149.5 AIO00633.1 - 7.6e-22 77.2 0.2 1.5e-21 76.2 0.2 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1935) AAA_16 PF13191.1 AIO00634.1 - 0.0085 16.0 0.0 0.018 15.0 0.0 1.4 1 1 0 1 1 1 1 AAA ATPase domain AAA_14 PF13173.1 AIO00634.1 - 0.031 14.1 0.0 0.047 13.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain cNMP_binding PF00027.24 AIO00636.1 - 4.4e-20 71.2 0.0 1.6e-05 24.5 0.0 5.5 5 1 0 5 5 5 4 Cyclic nucleotide-binding domain DnaJ PF00226.26 AIO00638.1 - 4.1e-21 74.4 0.1 8.1e-21 73.5 0.1 1.5 1 0 0 1 1 1 1 DnaJ domain DnaJ-X PF14308.1 AIO00638.1 - 0.00028 20.2 0.7 0.00056 19.2 0.5 1.4 1 0 0 1 1 1 1 X-domain of DnaJ-containing TRM13 PF05206.9 AIO00639.1 - 1.2e-62 211.5 0.0 8.1e-61 205.5 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase TRM13 zf-U11-48K PF05253.7 AIO00639.1 - 1.1e-10 41.0 1.0 2.6e-10 39.7 0.7 1.7 1 0 0 1 1 1 1 U11-48K-like CHHC zinc finger zf-TRM13_CCCH PF11722.3 AIO00639.1 - 1.6e-10 40.1 7.9 1.6e-10 40.1 5.5 2.6 3 0 0 3 3 3 1 CCCH zinc finger in TRM13 protein Methyltransf_32 PF13679.1 AIO00639.1 - 0.049 13.3 4.3 0.9 9.2 3.0 2.5 1 1 0 1 1 1 0 Methyltransferase domain ABC_membrane_2 PF06472.10 AIO00641.1 - 4.5e-73 245.8 5.2 6.5e-73 245.2 3.6 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 ABC_tran PF00005.22 AIO00641.1 - 3.5e-16 59.7 0.0 6.4e-16 58.8 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 AIO00641.1 - 0.075 12.9 0.0 0.12 12.2 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.1 AIO00641.1 - 0.24 11.6 0.0 0.39 11.0 0.0 1.2 1 0 0 1 1 1 0 AAA domain Apt1 PF10351.4 AIO00642.1 - 0.049 12.4 2.5 0.12 11.2 1.7 1.6 1 0 0 1 1 1 0 Golgi-body localisation protein domain Integrase_DNA PF02920.10 AIO00642.1 - 0.13 11.7 4.7 0.4 10.1 3.3 1.8 1 0 0 1 1 1 0 DNA binding domain of tn916 integrase GHMP_kinases_C PF08544.8 AIO00643.1 - 1.7e-16 60.1 0.4 3.4e-16 59.1 0.3 1.5 1 0 0 1 1 1 1 GHMP kinases C terminal GHMP_kinases_N PF00288.21 AIO00643.1 - 8.7e-16 57.7 0.5 2.2e-15 56.4 0.4 1.7 1 0 0 1 1 1 1 GHMP kinases N terminal domain Aa_trans PF01490.13 AIO00644.1 - 1.8e-46 158.4 40.6 2.3e-46 158.1 28.1 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.8 AIO00644.1 - 1.2e-09 37.4 17.7 1.2e-09 37.4 12.3 2.2 1 1 0 2 2 2 1 Tryptophan/tyrosine permease family Aa_trans PF01490.13 AIO00645.1 - 1.5e-45 155.3 36.3 1.8e-45 155.1 25.1 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein AA_permease_2 PF13520.1 AIO00645.1 - 6e-06 25.0 16.2 6e-06 25.0 11.2 2.8 1 1 2 3 3 3 2 Amino acid permease Trp_Tyr_perm PF03222.8 AIO00645.1 - 1.1e-05 24.4 14.3 1.1e-05 24.4 9.9 2.6 2 2 0 2 2 2 1 Tryptophan/tyrosine permease family Aa_trans PF01490.13 AIO00646.1 - 4.1e-44 150.6 33.8 5.4e-44 150.3 23.4 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein DUF1145 PF06611.7 AIO00646.1 - 2.7 7.6 8.0 9 6.0 0.3 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1145) FA_hydroxylase PF04116.8 AIO00647.1 - 5.4e-09 36.4 13.7 5.4e-09 36.4 9.5 2.3 2 1 0 2 2 2 1 Fatty acid hydroxylase superfamily Ribosomal_L7Ae PF01248.21 AIO00649.1 - 0.00011 21.5 0.7 0.00021 20.7 0.1 1.8 2 0 0 2 2 2 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Antimicrobial19 PF08225.6 AIO00649.1 - 0.025 13.9 0.1 0.057 12.8 0.1 1.5 1 0 0 1 1 1 0 Pseudin antimicrobial peptide FtsJ PF01728.14 AIO00653.1 - 1.8e-40 138.8 0.0 2.2e-40 138.5 0.0 1.1 1 0 0 1 1 1 1 FtsJ-like methyltransferase C2 PF00168.25 AIO00656.1 - 1.4e-20 72.9 0.0 2e-20 72.3 0.0 1.3 1 0 0 1 1 1 1 C2 domain CEP76-C2 PF15627.1 AIO00656.1 - 0.0047 16.4 0.0 0.0073 15.8 0.0 1.4 1 1 0 1 1 1 1 CEP76 C2 domain DUF2360 PF10152.4 AIO00656.1 - 7.2 6.8 10.3 53 4.0 7.1 2.0 1 1 0 1 1 1 0 Predicted coiled-coil domain-containing protein (DUF2360) Peptidase_M41 PF01434.13 AIO00658.1 - 6.9e-51 172.7 0.0 1.7e-50 171.4 0.0 1.7 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.24 AIO00658.1 - 1e-33 116.3 0.0 2e-33 115.3 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 AIO00658.1 - 0.00037 20.6 0.3 0.17 11.9 0.1 2.9 1 1 0 2 2 2 1 AAA domain AAA_5 PF07728.9 AIO00658.1 - 0.00056 19.6 0.6 0.12 12.0 0.3 2.5 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 AIO00658.1 - 0.0013 18.6 0.0 0.0034 17.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_17 PF13207.1 AIO00658.1 - 0.0022 18.7 0.2 0.014 16.1 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 AIO00658.1 - 0.0053 16.4 1.4 0.027 14.2 1.0 2.2 1 0 0 1 1 1 1 Part of AAA domain AAA_16 PF13191.1 AIO00658.1 - 0.02 14.8 0.8 0.12 12.3 0.5 2.3 1 1 0 1 1 1 0 AAA ATPase domain AAA_28 PF13521.1 AIO00658.1 - 0.021 14.7 0.0 0.021 14.7 0.0 2.3 3 0 0 3 3 3 0 AAA domain IstB_IS21 PF01695.12 AIO00658.1 - 0.027 13.8 1.0 0.067 12.6 0.7 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_33 PF13671.1 AIO00658.1 - 0.03 14.1 0.0 0.097 12.5 0.0 1.9 1 0 0 1 1 1 0 AAA domain RuvB_N PF05496.7 AIO00658.1 - 0.039 12.9 0.0 0.082 11.9 0.0 1.5 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus Mg_chelatase PF01078.16 AIO00658.1 - 0.089 11.9 0.3 0.18 10.9 0.2 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_18 PF13238.1 AIO00658.1 - 0.096 12.9 0.1 0.34 11.2 0.0 2.0 2 0 0 2 2 2 0 AAA domain Nodulin-like PF06813.8 AIO00660.1 - 5.5e-06 25.8 7.5 7.5e-06 25.3 5.2 1.2 1 0 0 1 1 1 1 Nodulin-like MFS_2 PF13347.1 AIO00660.1 - 0.0021 16.5 9.0 0.0021 16.5 6.2 1.8 1 1 1 2 2 2 1 MFS/sugar transport protein DUF21 PF01595.15 AIO00660.1 - 7.4 5.8 7.3 5.7 6.1 0.8 2.5 2 1 1 3 3 3 0 Domain of unknown function DUF21 MFS_1 PF07690.11 AIO00661.1 - 1.3e-08 34.0 51.1 9.7e-08 31.1 17.0 3.9 2 2 1 3 3 3 2 Major Facilitator Superfamily Nodulin-like PF06813.8 AIO00661.1 - 0.0017 17.6 17.0 0.024 13.8 11.8 2.2 1 1 0 1 1 1 1 Nodulin-like CesT PF05932.8 AIO00663.1 - 6.1e-15 55.1 0.8 1.3e-14 54.0 0.1 1.8 2 0 0 2 2 2 1 Tir chaperone protein (CesT) family DivIC PF04977.10 AIO00663.1 - 0.012 15.1 0.8 0.024 14.1 0.5 1.4 1 0 0 1 1 1 0 Septum formation initiator PRCC PF10253.4 AIO00663.1 - 0.02 15.5 1.6 0.029 15.0 1.1 1.1 1 0 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting ubiquitin PF00240.18 AIO00663.1 - 0.033 13.5 0.1 0.11 11.9 0.0 1.8 2 0 0 2 2 2 0 Ubiquitin family PGBA_C PF15437.1 AIO00665.1 - 0.022 14.8 4.7 0.058 13.5 3.3 1.7 1 0 0 1 1 1 0 Plasminogen-binding protein pgbA C-terminal C2 PF00168.25 AIO00666.1 - 7e-20 70.6 0.3 1.3e-19 69.8 0.2 1.5 1 0 0 1 1 1 1 C2 domain C2 PF00168.25 AIO00667.1 - 8.2e-21 73.6 0.1 1.1e-20 73.2 0.1 1.2 1 0 0 1 1 1 1 C2 domain Vpu PF00558.14 AIO00668.1 - 1.6 8.3 3.7 9.6 5.8 0.2 2.7 2 0 0 2 2 2 0 Vpu protein Ras PF00071.17 AIO00671.1 - 3e-23 81.9 0.5 5.8e-19 68.0 0.0 2.6 2 1 0 2 2 2 2 Ras family Miro PF08477.8 AIO00671.1 - 3.7e-14 53.2 0.3 9.5e-14 51.9 0.2 1.7 1 1 0 1 1 1 1 Miro-like protein GTP_EFTU PF00009.22 AIO00671.1 - 8.9e-09 35.0 0.3 1.6e-08 34.1 0.2 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Arf PF00025.16 AIO00671.1 - 2.3e-08 33.4 0.0 1.8e-06 27.2 0.0 2.3 2 0 0 2 2 2 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 AIO00671.1 - 3.8e-08 32.7 0.1 6e-08 32.1 0.0 1.4 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 AIO00671.1 - 7.6e-05 22.6 0.0 0.00039 20.3 0.0 2.2 2 1 0 2 2 2 1 50S ribosome-binding GTPase Dynamin_N PF00350.18 AIO00671.1 - 0.05 13.4 1.8 0.41 10.4 0.5 2.5 2 0 0 2 2 2 0 Dynamin family Aa_trans PF01490.13 AIO00672.1 - 6.6e-49 166.4 31.0 8.1e-49 166.1 21.5 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.8 AIO00672.1 - 1.6e-07 30.4 30.8 5.8e-07 28.6 21.3 1.7 1 1 0 1 1 1 1 Tryptophan/tyrosine permease family OapA_N PF08525.6 AIO00672.1 - 0.036 13.8 0.3 0.19 11.5 0.2 2.3 1 0 0 1 1 1 0 Opacity-associated protein A N-terminal motif Aa_trans PF01490.13 AIO00673.1 - 6.6e-49 166.4 31.0 8.1e-49 166.1 21.5 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.8 AIO00673.1 - 1.6e-07 30.4 30.8 5.8e-07 28.6 21.3 1.7 1 1 0 1 1 1 1 Tryptophan/tyrosine permease family OapA_N PF08525.6 AIO00673.1 - 0.036 13.8 0.3 0.19 11.5 0.2 2.3 1 0 0 1 1 1 0 Opacity-associated protein A N-terminal motif KIAA1430 PF13879.1 AIO00674.1 - 3.5e-19 69.0 0.2 5e-19 68.5 0.2 1.2 1 0 0 1 1 1 1 KIAA1430 homologue HCMV_UL139 PF12507.3 AIO00674.1 - 0.03 14.4 0.1 0.03 14.4 0.1 1.6 2 0 0 2 2 2 0 Human Cytomegalovirus UL139 protein DUF3279 PF11682.3 AIO00674.1 - 0.056 13.0 0.4 8.3 6.0 0.1 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3279) UPF0104 PF03706.8 AIO00675.1 - 0.0041 16.4 0.6 0.0041 16.4 0.4 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0104) WCOR413 PF05562.6 AIO00675.1 - 0.02 14.4 0.1 0.034 13.6 0.0 1.4 1 1 0 1 1 1 0 Cold acclimation protein WCOR413 Imm_superinfect PF14373.1 AIO00675.1 - 0.046 13.3 0.2 0.078 12.6 0.1 1.5 1 0 0 1 1 1 0 Superinfection immunity protein DUF2427 PF10348.4 AIO00675.1 - 0.055 13.0 0.5 0.071 12.6 0.4 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF2427) Bax1-I PF01027.15 AIO00675.1 - 0.06 12.9 0.6 0.066 12.8 0.4 1.0 1 0 0 1 1 1 0 Inhibitor of apoptosis-promoting Bax1 stn_TNFRSF12A PF12191.3 AIO00675.1 - 0.075 13.0 0.8 0.39 10.7 0.1 1.9 1 1 1 2 2 2 0 Tumour necrosis factor receptor stn_TNFRSF12A_TNFR domain DUF4013 PF13197.1 AIO00675.1 - 0.11 11.8 0.8 0.14 11.5 0.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4013) DUF3397 PF11877.3 AIO00675.1 - 0.12 12.3 0.2 0.17 11.9 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3397) CD20 PF04103.10 AIO00675.1 - 0.14 12.0 1.0 0.22 11.4 0.7 1.3 1 1 0 1 1 1 0 CD20-like family DUF4233 PF14017.1 AIO00675.1 - 0.15 12.0 2.5 0.17 11.8 1.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4233) DUF3693 PF12472.3 AIO00675.1 - 0.19 11.3 1.0 0.32 10.6 0.3 1.7 1 1 1 2 2 2 0 Phage related protein DUF4229 PF14012.1 AIO00675.1 - 0.41 10.5 4.2 0.63 9.9 2.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4229) SH3BGR PF04908.10 AIO00680.1 - 0.26 11.2 1.7 20 5.1 0.1 2.6 2 0 0 2 2 2 0 SH3-binding, glutamic acid-rich protein DUF4217 PF13959.1 AIO00681.1 - 1e-05 24.9 0.0 2.3e-05 23.8 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) DUF4090 PF13319.1 AIO00681.1 - 0.074 13.0 0.0 0.32 10.9 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF4090) RRM_1 PF00076.17 AIO00683.1 - 6e-05 22.6 0.0 0.00011 21.6 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 AIO00683.1 - 0.0019 18.1 0.0 0.0033 17.3 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) YhfH PF14149.1 AIO00683.1 - 0.0076 16.0 1.0 0.084 12.6 0.0 2.4 2 0 0 2 2 2 1 YhfH-like protein SseC PF04888.7 AIO00684.1 - 1.3 8.2 4.1 1.7 7.8 2.8 1.3 1 0 0 1 1 1 0 Secretion system effector C (SseC) like family SET PF00856.23 AIO00686.1 - 0.0013 19.0 0.0 0.0088 16.3 0.0 2.4 1 1 0 1 1 1 1 SET domain WLM PF08325.5 AIO00686.1 - 0.086 12.7 0.0 0.19 11.5 0.0 1.5 1 0 0 1 1 1 0 WLM domain BPL_LplA_LipB PF03099.14 AIO00687.1 - 9.2e-15 54.7 0.0 1.9e-14 53.7 0.0 1.5 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family DUF3015 PF11220.3 AIO00687.1 - 0.033 13.7 0.0 0.06 12.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3015) Guanylate_cyc_2 PF09778.4 AIO00687.1 - 0.13 11.3 0.0 0.25 10.4 0.0 1.4 1 0 0 1 1 1 0 Guanylylate cyclase AIP3 PF03915.8 AIO00688.1 - 0.006 15.5 1.8 0.0087 15.0 1.2 1.1 1 0 0 1 1 1 1 Actin interacting protein 3 Baculo_PEP_C PF04513.7 AIO00688.1 - 0.15 11.9 0.3 0.26 11.1 0.2 1.4 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Cluap1 PF10234.4 AIO00688.1 - 0.19 10.8 6.1 0.46 9.6 4.0 1.6 1 1 0 1 1 1 0 Clusterin-associated protein-1 HrpB7 PF09486.5 AIO00688.1 - 0.24 11.2 8.4 1.6 8.6 0.1 2.3 2 0 0 2 2 2 0 Bacterial type III secretion protein (HrpB7) Occludin_ELL PF07303.8 AIO00688.1 - 2.3 8.9 3.1 3.8 8.3 2.1 1.3 1 0 0 1 1 1 0 Occludin homology domain DUF4498 PF14926.1 AIO00689.1 - 2.8e-17 62.6 0.0 8e-12 44.8 0.0 4.5 4 1 0 4 4 4 3 Domain of unknown function (DUF4498) EMP24_GP25L PF01105.19 AIO00690.1 - 2.4e-24 86.0 0.0 2.7e-24 85.8 0.0 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Gypsy PF07253.6 AIO00690.1 - 0.047 12.0 0.2 0.056 11.7 0.2 1.0 1 0 0 1 1 1 0 Gypsy protein EMP24_GP25L PF01105.19 AIO00691.1 - 5.5e-22 78.3 0.1 5.9e-22 78.2 0.0 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD LigT_PEase PF02834.11 AIO00691.1 - 0.096 12.6 0.0 0.3 11.0 0.0 1.8 1 1 1 2 2 2 0 LigT like Phosphoesterase Peptidase_M20 PF01546.23 AIO00692.1 - 1.8e-28 99.3 0.0 2.3e-28 99.0 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 AIO00692.1 - 7.1e-07 28.9 0.0 1.9e-06 27.5 0.0 1.7 1 0 0 1 1 1 1 Peptidase dimerisation domain TMEM219 PF14940.1 AIO00692.1 - 0.04 13.0 0.7 0.083 11.9 0.5 1.4 1 0 0 1 1 1 0 Transmembrane 219 GST_C_4 PF14834.1 AIO00692.1 - 0.046 13.6 0.0 0.086 12.7 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Abhydrolase_6 PF12697.2 AIO00693.1 - 4.7e-29 101.8 0.1 6.7e-29 101.3 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 AIO00693.1 - 4.2e-24 84.9 0.0 1.5e-23 83.1 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 AIO00693.1 - 1.3e-21 76.2 0.0 2.7e-21 75.2 0.0 1.6 1 0 0 1 1 1 1 Putative lysophospholipase Peptidase_S9 PF00326.16 AIO00693.1 - 5.7e-10 38.7 0.2 3.3e-05 23.1 0.0 2.1 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_1 PF00561.15 AIO00693.1 - 7.4e-09 35.5 0.0 4.6e-08 32.9 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S15 PF02129.13 AIO00693.1 - 2.2e-05 24.0 0.1 0.0011 18.5 0.0 2.1 2 0 0 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) PGAP1 PF07819.8 AIO00693.1 - 0.00061 19.4 0.0 0.00083 18.9 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_3 PF07859.8 AIO00693.1 - 0.0084 15.7 0.0 0.016 14.7 0.0 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Esterase PF00756.15 AIO00693.1 - 0.01 15.2 0.0 0.013 14.9 0.0 1.3 1 0 0 1 1 1 0 Putative esterase PhoPQ_related PF10142.4 AIO00693.1 - 0.011 14.2 0.0 0.014 13.9 0.0 1.1 1 0 0 1 1 1 0 PhoPQ-activated pathogenicity-related protein Abhydrolase_8 PF06259.7 AIO00693.1 - 0.011 15.2 0.0 0.026 14.0 0.0 1.6 2 0 0 2 2 2 0 Alpha/beta hydrolase DLH PF01738.13 AIO00693.1 - 0.011 15.0 0.0 2.1 7.6 0.0 2.2 2 0 0 2 2 2 0 Dienelactone hydrolase family Thioesterase PF00975.15 AIO00693.1 - 0.016 15.4 0.0 0.031 14.5 0.0 1.4 1 0 0 1 1 1 0 Thioesterase domain Ser_hydrolase PF06821.8 AIO00693.1 - 0.024 14.2 0.0 0.96 9.0 0.0 2.2 1 1 0 1 1 1 0 Serine hydrolase DUF2920 PF11144.3 AIO00693.1 - 0.037 13.0 0.0 1.1 8.2 0.0 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF2920) LCAT PF02450.10 AIO00693.1 - 0.073 12.0 0.0 0.088 11.7 0.0 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase Lipase_3 PF01764.20 AIO00693.1 - 0.083 12.5 0.0 0.15 11.6 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) LRR_4 PF12799.2 AIO00695.1 - 2.2e-12 46.2 19.1 0.0049 16.4 0.0 7.5 7 1 1 8 8 8 6 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 AIO00695.1 - 1.4e-05 24.7 12.3 0.13 12.0 0.6 5.8 5 0 0 5 5 5 4 Leucine rich repeat LRR_1 PF00560.28 AIO00695.1 - 0.19 11.8 19.8 54 4.3 0.6 8.6 6 2 1 7 7 7 0 Leucine Rich Repeat Cyt-b5 PF00173.23 AIO00696.1 - 7.3e-06 25.6 0.0 1.1e-05 25.1 0.0 1.3 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Cyt-b5 PF00173.23 AIO00697.1 - 1e-07 31.6 0.0 1.4e-07 31.2 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain HH_signal PF01085.13 AIO00697.1 - 0.087 12.3 0.2 0.12 11.9 0.2 1.2 1 0 0 1 1 1 0 Hedgehog amino-terminal signalling domain RskA PF10099.4 AIO00697.1 - 0.1 12.3 3.1 0.15 11.8 1.5 1.6 2 0 0 2 2 2 0 Anti-sigma-K factor rskA Cyt-b5 PF00173.23 AIO00698.1 - 1.5e-06 27.9 0.0 2.5e-06 27.2 0.0 1.3 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Cyt-b5 PF00173.23 AIO00699.1 - 7.4e-08 32.0 0.0 1.1e-07 31.5 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Cyt-b5 PF00173.23 AIO00700.1 - 4.9e-08 32.6 0.0 8e-08 31.9 0.0 1.3 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain DUF3638 PF12340.3 AIO00701.1 - 3.3e-27 94.9 0.0 7.5e-24 83.9 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF3638) DUF3645 PF12359.3 AIO00701.1 - 9.6e-17 59.8 0.5 2.7e-16 58.3 0.4 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF3645) zf-RanBP PF00641.13 AIO00701.1 - 9.1e-08 31.0 22.8 3.4e-05 22.8 3.7 3.5 3 0 0 3 3 3 3 Zn-finger in Ran binding protein and others Thioredoxin_8 PF13905.1 AIO00701.1 - 7.2e-05 22.8 0.0 0.00017 21.6 0.0 1.7 1 0 0 1 1 1 1 Thioredoxin-like ubiquitin PF00240.18 AIO00701.1 - 0.0022 17.3 0.0 0.0053 16.1 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin family H_PPase PF03030.11 AIO00702.1 - 5.4e-253 841.2 29.0 7.3e-253 840.8 20.1 1.1 1 0 0 1 1 1 1 Inorganic H+ pyrophosphatase DUF805 PF05656.9 AIO00702.1 - 1.6 8.5 8.6 0.94 9.3 0.7 3.3 2 2 0 2 2 2 0 Protein of unknown function (DUF805) LRR_6 PF13516.1 AIO00703.1 - 0.0055 16.6 7.9 2.1 8.6 0.1 4.3 4 1 0 4 4 4 2 Leucine Rich repeat LRR_4 PF12799.2 AIO00703.1 - 0.024 14.2 3.5 0.031 13.8 0.9 2.6 2 0 0 2 2 2 0 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 AIO00703.1 - 3.5 8.0 12.1 2.6 8.4 0.2 4.3 4 0 0 4 4 4 0 Leucine Rich Repeat HTH_23 PF13384.1 AIO00704.1 - 0.03 13.9 0.1 0.076 12.6 0.0 1.7 1 0 0 1 1 1 0 Homeodomain-like domain MT PF12777.2 AIO00706.1 - 5.9e-06 25.2 0.1 5.9e-06 25.2 0.0 2.2 2 0 0 2 2 2 1 Microtubule-binding stalk of dynein motor AAA_13 PF13166.1 AIO00706.1 - 7.7 4.8 15.7 1.3 7.3 0.9 3.5 4 0 0 4 4 4 0 AAA domain ABC_tran PF00005.22 AIO00707.1 - 1.9e-24 86.5 0.0 3.1e-24 85.8 0.0 1.4 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.18 AIO00707.1 - 1e-22 80.8 9.1 1.6e-22 80.2 6.3 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region AAA_21 PF13304.1 AIO00707.1 - 0.00034 20.6 0.0 0.19 11.6 0.0 2.3 2 0 0 2 2 2 2 AAA domain SMC_N PF02463.14 AIO00707.1 - 0.00054 19.2 0.0 0.059 12.6 0.0 2.3 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 AIO00707.1 - 0.00064 19.1 0.3 0.0082 15.6 0.0 2.3 2 0 0 2 2 2 1 P-loop containing region of AAA domain T2SE PF00437.15 AIO00707.1 - 0.0098 14.8 0.0 0.018 13.9 0.0 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_25 PF13481.1 AIO00707.1 - 0.078 12.3 0.0 0.17 11.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.18 AIO00707.1 - 0.088 12.7 0.1 0.2 11.6 0.1 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_10 PF12846.2 AIO00707.1 - 0.1 11.9 0.0 0.21 11.0 0.0 1.4 1 0 0 1 1 1 0 AAA-like domain DUF87 PF01935.12 AIO00707.1 - 0.11 12.2 0.1 0.21 11.3 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function DUF87 Miro PF08477.8 AIO00707.1 - 0.18 12.2 0.4 0.44 11.0 0.2 1.6 1 0 0 1 1 1 0 Miro-like protein ABC_membrane PF00664.18 AIO00708.1 - 1.9e-27 96.3 8.0 2.9e-27 95.7 5.5 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region CAP_GLY PF01302.20 AIO00708.1 - 0.0056 16.3 0.3 0.024 14.3 0.2 2.0 1 1 0 1 1 1 1 CAP-Gly domain ABC_membrane PF00664.18 AIO00709.1 - 6.1e-25 88.1 6.0 9.4e-25 87.5 4.1 1.3 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.22 AIO00709.1 - 1.1e-24 87.2 0.0 3.2e-24 85.7 0.0 1.7 2 0 0 2 2 2 1 ABC transporter AAA_21 PF13304.1 AIO00709.1 - 0.00039 20.4 0.0 0.19 11.6 0.0 2.2 2 0 0 2 2 2 2 AAA domain SMC_N PF02463.14 AIO00709.1 - 0.0006 19.1 0.0 0.071 12.3 0.0 2.1 1 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_25 PF13481.1 AIO00709.1 - 0.0031 16.9 0.1 0.17 11.2 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.1 AIO00709.1 - 0.0039 16.6 0.0 0.0082 15.6 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain T2SE PF00437.15 AIO00709.1 - 0.009 14.9 0.0 0.018 13.9 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_16 PF13191.1 AIO00709.1 - 0.06 13.3 0.3 0.23 11.4 0.2 2.2 1 1 0 1 1 1 0 AAA ATPase domain AAA_10 PF12846.2 AIO00709.1 - 0.085 12.2 0.0 0.21 10.9 0.0 1.6 1 0 0 1 1 1 0 AAA-like domain MMR_HSR1 PF01926.18 AIO00709.1 - 0.087 12.7 0.1 0.2 11.6 0.1 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase DUF87 PF01935.12 AIO00709.1 - 0.12 12.1 0.1 0.21 11.3 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function DUF87 Miro PF08477.8 AIO00709.1 - 0.21 12.0 0.4 0.44 11.0 0.2 1.5 1 0 0 1 1 1 0 Miro-like protein ABC_membrane PF00664.18 AIO00710.1 - 3.4e-18 66.0 4.2 4.9e-18 65.5 2.9 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region CAP_GLY PF01302.20 AIO00710.1 - 0.0039 16.8 0.4 0.025 14.2 0.2 2.1 2 0 0 2 2 2 1 CAP-Gly domain CAP_GLY PF01302.20 AIO00711.1 - 0.00017 21.1 0.4 0.0035 17.0 0.2 2.3 2 0 0 2 2 2 1 CAP-Gly domain PP2C PF00481.16 AIO00714.1 - 1e-33 116.8 0.0 5e-29 101.4 0.1 2.4 2 0 0 2 2 2 2 Protein phosphatase 2C zf-UBP PF02148.14 AIO00714.1 - 0.3 11.2 10.1 0.65 10.1 7.0 1.5 1 0 0 1 1 1 0 Zn-finger in ubiquitin-hydrolases and other protein CSD PF00313.17 AIO00716.1 - 9e-11 41.4 0.1 5.9e-07 29.1 0.0 2.5 2 0 0 2 2 2 2 'Cold-shock' DNA-binding domain CSD PF00313.17 AIO00717.1 - 9.2e-05 22.1 0.0 0.47 10.2 0.0 3.5 3 1 0 3 3 3 2 'Cold-shock' DNA-binding domain DUF4592 PF15262.1 AIO00717.1 - 1.6 9.3 5.8 5.7 7.5 4.0 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4592) Tho2 PF11262.3 AIO00718.1 - 0.067 12.2 5.0 0.33 9.9 0.1 2.3 2 0 0 2 2 2 0 Transcription factor/nuclear export subunit protein 2 SPRY PF00622.23 AIO00719.1 - 0.0033 17.4 0.0 0.0065 16.5 0.0 1.5 1 0 0 1 1 1 1 SPRY domain zf-LSD1 PF06943.7 AIO00722.1 - 5.1e-12 45.1 6.6 5.1e-12 45.1 4.6 2.9 2 1 1 3 3 3 1 LSD1 zinc finger zf-RING_3 PF14369.1 AIO00722.1 - 0.73 9.8 16.1 0.8 9.7 1.1 2.7 1 1 2 3 3 3 0 zinc-finger zinc_ribbon_5 PF13719.1 AIO00722.1 - 1 8.9 0.0 1 8.9 0.0 3.9 3 1 2 5 5 5 0 zinc-ribbon domain zinc_ribbon_4 PF13717.1 AIO00722.1 - 1 9.0 0.0 1 9.0 0.0 3.9 3 1 1 5 5 5 0 zinc-ribbon domain Mu-like_Com PF10122.4 AIO00722.1 - 1.1 8.3 13.7 0.62 9.1 0.4 2.6 1 1 2 3 3 3 0 Mu-like prophage protein Com Tmemb_55A PF09788.4 AIO00722.1 - 1.6 7.7 16.2 4 6.4 11.2 1.6 1 1 0 1 1 1 0 Transmembrane protein 55A Stc1 PF12898.2 AIO00722.1 - 4.6 7.3 8.1 0.48 10.5 0.3 2.3 1 1 1 2 2 2 0 Stc1 domain OrfB_Zn_ribbon PF07282.6 AIO00722.1 - 4.9 6.8 11.0 2.7 7.6 1.8 2.6 1 1 2 3 3 3 0 Putative transposase DNA-binding domain HypA PF01155.14 AIO00722.1 - 8.9 6.0 12.0 2.8 7.6 0.6 2.2 1 1 1 2 2 2 0 Hydrogenase expression/synthesis hypA family Sirohm_synth_M PF14824.1 AIO00723.1 - 0.0029 16.5 0.5 0.0057 15.6 0.0 1.8 2 0 0 2 2 2 1 Sirohaem biosynthesis protein central ABC_tran PF00005.22 AIO00726.1 - 4.9e-45 153.1 0.0 4.3e-27 95.0 0.0 2.6 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 AIO00726.1 - 2.3e-35 122.3 14.9 1.9e-21 76.7 2.1 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.14 AIO00726.1 - 1.2e-09 37.7 0.0 0.017 14.3 0.0 4.0 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 AIO00726.1 - 1.4e-07 31.7 0.0 0.53 10.2 0.0 4.0 4 0 0 4 4 4 2 AAA domain T2SE PF00437.15 AIO00726.1 - 2.1e-07 30.1 0.0 0.012 14.5 0.0 2.3 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_29 PF13555.1 AIO00726.1 - 2.4e-07 30.1 0.2 0.022 14.2 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_25 PF13481.1 AIO00726.1 - 1.8e-06 27.5 0.1 0.07 12.5 0.0 2.6 2 0 0 2 2 2 2 AAA domain FtsK_SpoIIIE PF01580.13 AIO00726.1 - 9.4e-06 25.2 0.1 0.11 11.9 0.0 2.6 2 0 0 2 2 2 2 FtsK/SpoIIIE family AAA_16 PF13191.1 AIO00726.1 - 5.6e-05 23.1 1.7 0.27 11.1 0.0 3.3 4 0 0 4 4 2 2 AAA ATPase domain AAA_10 PF12846.2 AIO00726.1 - 0.0001 21.8 0.3 0.2 11.0 0.0 2.3 2 0 0 2 2 2 2 AAA-like domain MMR_HSR1 PF01926.18 AIO00726.1 - 0.00014 21.8 0.0 0.075 12.9 0.0 2.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_23 PF13476.1 AIO00726.1 - 0.00016 22.1 0.0 0.14 12.4 0.0 2.1 2 0 0 2 2 2 1 AAA domain CAP_GLY PF01302.20 AIO00726.1 - 0.00092 18.8 0.0 0.0025 17.4 0.0 1.7 1 0 0 1 1 1 1 CAP-Gly domain Miro PF08477.8 AIO00726.1 - 0.0014 19.0 0.7 0.82 10.1 0.2 2.5 2 0 0 2 2 2 1 Miro-like protein AAA_22 PF13401.1 AIO00726.1 - 0.0015 18.7 0.5 1.3 9.1 0.0 3.3 4 0 0 4 4 2 1 AAA domain TrwB_AAD_bind PF10412.4 AIO00726.1 - 0.0015 17.2 0.2 0.44 9.1 0.0 2.2 2 0 0 2 2 2 1 Type IV secretion-system coupling protein DNA-binding domain ATP-synt_ab PF00006.20 AIO00726.1 - 0.0028 17.1 2.8 0.14 11.6 1.5 2.8 2 1 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain DUF87 PF01935.12 AIO00726.1 - 0.0062 16.3 5.3 0.18 11.5 0.1 2.2 2 0 0 2 2 2 1 Domain of unknown function DUF87 DUF258 PF03193.11 AIO00726.1 - 0.0063 15.7 0.3 1.3 8.1 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function, DUF258 ArgK PF03308.11 AIO00726.1 - 0.013 14.3 0.8 3.1 6.4 0.0 2.3 2 0 0 2 2 2 0 ArgK protein MobB PF03205.9 AIO00726.1 - 0.019 14.7 1.4 0.97 9.1 0.1 2.7 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B NACHT PF05729.7 AIO00726.1 - 0.026 14.2 1.6 3.2 7.3 0.1 2.4 2 0 0 2 2 2 0 NACHT domain AAA_33 PF13671.1 AIO00726.1 - 0.04 13.7 0.3 9.6 6.0 0.1 2.7 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.1 AIO00726.1 - 0.072 13.9 1.5 2.1 9.1 0.1 2.8 2 0 0 2 2 2 0 AAA domain Pox_A32 PF04665.7 AIO00726.1 - 0.074 12.3 0.6 5.8 6.1 0.1 2.3 2 0 0 2 2 2 0 Poxvirus A32 protein cobW PF02492.14 AIO00726.1 - 0.084 12.3 3.3 5.2 6.4 0.2 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_5 PF07728.9 AIO00726.1 - 0.11 12.2 0.1 7.4 6.2 0.0 2.6 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Dynamin_N PF00350.18 AIO00726.1 - 0.12 12.2 2.4 3 7.6 0.1 2.2 2 0 0 2 2 2 0 Dynamin family Viral_helicase1 PF01443.13 AIO00726.1 - 0.18 11.3 0.1 13 5.2 0.0 2.4 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase Zeta_toxin PF06414.7 AIO00726.1 - 0.28 10.2 0.0 18 4.3 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin DUF2075 PF09848.4 AIO00726.1 - 0.41 9.5 0.8 2.5 6.9 0.0 2.1 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) Adeno_IVa2 PF02456.10 AIO00726.1 - 0.46 9.0 0.1 4.1 5.9 0.0 2.0 2 0 0 2 2 2 0 Adenovirus IVa2 protein AAA_18 PF13238.1 AIO00726.1 - 0.51 10.6 0.9 6.1 7.1 0.1 2.3 2 0 0 2 2 2 0 AAA domain AIG1 PF04548.11 AIO00726.1 - 0.58 9.2 0.7 6.8 5.7 0.0 2.3 2 0 0 2 2 2 0 AIG1 family DAP3 PF10236.4 AIO00726.1 - 0.7 8.7 1.7 13 4.5 0.0 2.2 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 Arch_ATPase PF01637.13 AIO00726.1 - 0.73 9.4 0.0 34 4.0 0.0 2.3 2 0 0 2 2 2 0 Archaeal ATPase LRR_4 PF12799.2 AIO00728.1 - 1.6e-08 33.9 0.0 0.0029 17.2 0.0 3.7 2 1 3 5 5 5 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 AIO00728.1 - 1.4e-07 31.1 0.0 0.0011 18.6 0.0 3.2 1 1 3 4 4 4 4 Leucine rich repeat LRRNT_2 PF08263.7 AIO00728.1 - 0.0024 17.7 0.3 0.011 15.6 0.2 2.2 1 0 0 1 1 1 1 Leucine rich repeat N-terminal domain LRR_4 PF12799.2 AIO00729.1 - 1.1e-05 24.9 0.3 3.5 7.3 0.0 3.4 3 0 0 3 3 3 3 Leucine Rich repeats (2 copies) Mucin PF01456.12 AIO00729.1 - 0.00049 19.8 36.8 0.00049 19.8 25.5 2.1 2 0 0 2 2 2 1 Mucin-like glycoprotein LRR_1 PF00560.28 AIO00729.1 - 0.0023 17.7 0.1 12 6.3 0.0 4.5 4 0 0 4 4 4 1 Leucine Rich Repeat LRR_8 PF13855.1 AIO00729.1 - 0.0095 15.6 0.3 0.075 12.8 0.1 2.2 2 1 0 2 2 2 1 Leucine rich repeat COX4 PF02936.9 AIO00729.1 - 0.033 13.9 0.0 0.094 12.4 0.0 1.8 1 0 0 1 1 1 0 Cytochrome c oxidase subunit IV LRR_1 PF00560.28 AIO00730.1 - 1.4e-06 27.5 0.1 32 5.0 0.0 6.7 7 0 0 7 7 7 1 Leucine Rich Repeat LRR_4 PF12799.2 AIO00730.1 - 0.0006 19.3 0.0 1.4 8.5 0.0 3.8 4 1 1 5 5 5 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 AIO00730.1 - 0.0017 18.0 0.0 0.72 9.6 0.0 2.6 2 0 0 2 2 2 2 Leucine rich repeat Kei1 PF08552.6 AIO00731.1 - 0.1 12.2 0.0 0.2 11.3 0.0 1.4 1 0 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 LRR_4 PF12799.2 AIO00732.1 - 6.1e-19 67.2 2.5 0.08 12.5 0.1 10.7 8 2 4 12 12 12 5 Leucine Rich repeats (2 copies) LRR_6 PF13516.1 AIO00732.1 - 2.5e-15 54.7 6.3 0.37 11.0 0.0 11.7 13 0 0 13 13 13 5 Leucine Rich repeat LRR_8 PF13855.1 AIO00732.1 - 2.1e-06 27.3 14.0 4.1 7.2 0.2 8.5 9 2 1 10 10 10 4 Leucine rich repeat LRR_1 PF00560.28 AIO00732.1 - 0.18 11.9 24.1 34 5.0 0.0 11.0 11 3 1 12 12 12 0 Leucine Rich Repeat Y_phosphatase3 PF13350.1 AIO00736.1 - 0.095 12.9 0.0 0.18 12.0 0.0 1.4 1 0 0 1 1 1 0 Tyrosine phosphatase family Pkinase PF00069.20 AIO00737.1 - 3.4e-37 128.0 0.0 2.4e-26 92.4 0.0 2.6 3 0 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.12 AIO00737.1 - 5.2e-21 74.8 0.0 3.3e-19 68.9 0.0 2.8 2 1 0 2 2 2 1 Protein tyrosine kinase PH_3 PF14593.1 AIO00737.1 - 0.00022 21.0 0.0 0.00057 19.7 0.0 1.6 1 0 0 1 1 1 1 PH domain Kinase-like PF14531.1 AIO00737.1 - 0.029 13.3 0.0 0.052 12.5 0.0 1.3 1 0 0 1 1 1 0 Kinase-like L51_S25_CI-B8 PF05047.11 AIO00739.1 - 1.2e-08 34.6 0.1 3.5e-08 33.0 0.0 1.9 2 0 0 2 2 2 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain LysR_substrate PF03466.15 AIO00739.1 - 0.021 13.9 0.5 0.47 9.5 0.0 2.2 2 0 0 2 2 2 0 LysR substrate binding domain DUF1658 PF07871.6 AIO00741.1 - 0.02 14.4 0.4 0.041 13.4 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1658) Cmc1 PF08583.5 AIO00742.1 - 0.033 13.9 2.9 0.074 12.8 2.0 1.6 1 1 0 1 1 1 0 Cytochrome c oxidase biogenesis protein Cmc1 like Ribosomal_L36 PF00444.13 AIO00743.1 - 0.0012 18.8 1.7 0.0024 17.7 1.2 1.5 1 0 0 1 1 1 1 Ribosomal protein L36 TP_methylase PF00590.15 AIO00744.1 - 4.4e-18 65.7 0.0 7.3e-18 65.0 0.0 1.4 1 1 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases DUF4434 PF14488.1 AIO00744.1 - 0.0028 17.3 0.0 0.0047 16.6 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4434) NTPase_I-T PF01931.13 AIO00745.1 - 6e-65 218.0 0.0 6.7e-65 217.8 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function DUF84 Thiolase_N PF00108.18 AIO00746.1 - 6.7e-60 202.2 0.6 8.7e-60 201.9 0.4 1.1 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 AIO00746.1 - 2e-33 114.4 0.0 6e-33 112.8 0.0 1.8 1 0 0 1 1 1 1 Thiolase, C-terminal domain SpoVAD PF07451.6 AIO00746.1 - 0.00016 20.2 0.1 0.00031 19.3 0.1 1.4 1 0 0 1 1 1 1 Stage V sporulation protein AD (SpoVAD) ketoacyl-synt PF00109.21 AIO00746.1 - 0.00024 20.6 5.1 0.00048 19.6 2.8 1.9 1 1 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain FAE1_CUT1_RppA PF08392.7 AIO00746.1 - 0.0024 16.9 0.2 0.0043 16.1 0.1 1.3 1 0 0 1 1 1 1 FAE1/Type III polyketide synthase-like protein zf-MYND PF01753.13 AIO00747.1 - 4.7e-11 42.3 9.7 4.7e-11 42.3 6.7 2.1 2 0 0 2 2 2 1 MYND finger zf-Mss51 PF13824.1 AIO00747.1 - 0.97 9.3 7.6 2.8 7.8 5.3 1.8 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 Sld5 PF05916.6 AIO00748.1 - 1.4e-06 28.5 0.0 1.9e-06 28.1 0.0 1.2 1 0 0 1 1 1 1 GINS complex protein DUF1682 PF07946.9 AIO00750.1 - 5.8 5.6 7.0 11 4.8 4.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) UME PF08064.8 AIO00751.1 - 0.21 11.5 3.1 0.62 10.0 0.1 3.0 3 0 0 3 3 3 0 UME (NUC010) domain Fimbrial_CS1 PF04449.7 AIO00751.1 - 0.28 11.2 1.5 0.45 10.5 0.0 1.9 2 0 0 2 2 2 0 CS1 type fimbrial major subunit PPR_3 PF13812.1 AIO00752.1 - 0.0017 18.4 4.1 14 6.2 0.1 4.7 4 0 0 4 4 4 3 Pentatricopeptide repeat domain Cullin_Nedd8 PF10557.4 AIO00754.1 - 1.4e-15 56.8 0.6 3.9e-15 55.4 0.4 1.8 1 0 0 1 1 1 1 Cullin protein neddylation domain Cullin PF00888.17 AIO00754.1 - 1.5e-05 23.7 0.0 7e-05 21.5 0.0 1.9 1 1 0 1 1 1 1 Cullin family SKG6 PF08693.5 AIO00755.1 - 1.1 8.6 3.4 2.3 7.6 2.4 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain NAP PF00956.13 AIO00757.1 - 2.9e-77 259.1 0.3 2.9e-77 259.1 0.2 2.0 2 0 0 2 2 2 1 Nucleosome assembly protein (NAP) Nop14 PF04147.7 AIO00757.1 - 0.065 11.1 16.6 0.088 10.7 11.5 1.2 1 0 0 1 1 1 0 Nop14-like family HAUS6_N PF14661.1 AIO00757.1 - 0.12 11.7 0.5 0.3 10.3 0.3 1.7 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus PBP1_TM PF14812.1 AIO00757.1 - 0.32 11.3 22.0 3 8.1 2.1 2.8 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF2457 PF10446.4 AIO00757.1 - 0.42 9.2 27.5 0.62 8.7 11.7 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2457) RNase_H2_suC PF08615.6 AIO00757.1 - 0.73 9.6 8.4 60 3.4 5.9 2.4 1 1 0 1 1 1 0 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) Cwf_Cwc_15 PF04889.7 AIO00757.1 - 1.4 8.5 18.9 0.7 9.5 5.8 2.5 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein Nucleoplasmin PF03066.10 AIO00757.1 - 1.7 8.1 23.3 1.8 8.0 9.8 2.4 2 0 0 2 2 2 0 Nucleoplasmin NOA36 PF06524.7 AIO00757.1 - 3.7 6.7 16.9 0.39 9.9 6.9 2.1 2 0 0 2 2 2 0 NOA36 protein Spt5_N PF11942.3 AIO00757.1 - 6.3 7.4 27.8 1.3 9.6 7.0 3.4 3 0 0 3 3 3 0 Spt5 transcription elongation factor, acidic N-terminal Sigma70_ner PF04546.8 AIO00757.1 - 8.3 5.9 19.2 5 6.6 7.7 2.7 2 0 0 2 2 2 0 Sigma-70, non-essential region SURF2 PF05477.6 AIO00757.1 - 8.4 5.4 13.2 2.4 7.1 0.7 2.4 2 0 0 2 2 2 0 Surfeit locus protein 2 (SURF2) TRAM_LAG1_CLN8 PF03798.11 AIO00758.1 - 6.9e-37 126.9 22.0 6.9e-37 126.9 15.2 2.1 2 1 0 2 2 2 1 TLC domain DUF4190 PF13828.1 AIO00759.1 - 0.05 13.1 1.6 0.065 12.7 1.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4190) PepSY_TM PF03929.11 AIO00759.1 - 0.079 13.3 1.9 0.079 13.3 1.3 2.0 2 0 0 2 2 2 0 PepSY-associated TM helix MerC PF03203.9 AIO00759.1 - 0.17 12.2 1.2 0.17 12.2 0.9 1.1 1 0 0 1 1 1 0 MerC mercury resistance protein Aa_trans PF01490.13 AIO00760.1 - 5.5e-29 100.8 17.4 7.2e-29 100.4 12.1 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein AA_permease_2 PF13520.1 AIO00760.1 - 5.8e-09 34.9 22.9 7.1e-09 34.6 15.9 1.0 1 0 0 1 1 1 1 Amino acid permease Trp_Tyr_perm PF03222.8 AIO00760.1 - 9.9e-09 34.4 11.5 2e-08 33.4 8.0 1.5 1 0 0 1 1 1 1 Tryptophan/tyrosine permease family DUF3487 PF11990.3 AIO00760.1 - 3.7 6.9 6.8 0.32 10.3 0.1 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF3487) Pex24p PF06398.6 AIO00760.1 - 7.7 5.1 7.1 1.8 7.2 1.8 1.9 2 0 0 2 2 2 0 Integral peroxisomal membrane peroxin Pkinase PF00069.20 AIO00761.1 - 1.8e-18 66.6 0.0 2.6e-18 66.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AIO00761.1 - 1.3e-13 50.6 0.0 2.1e-09 36.8 0.0 2.2 1 1 1 2 2 2 2 Protein tyrosine kinase HAMP PF00672.20 AIO00762.1 - 0.011 15.8 0.0 0.038 14.1 0.0 2.0 1 1 0 1 1 1 0 HAMP domain INSIG PF07281.7 AIO00762.1 - 0.14 11.5 3.1 1.2 8.4 0.1 2.3 2 0 0 2 2 2 0 Insulin-induced protein (INSIG) IlvB_leader PF08049.6 AIO00762.1 - 0.71 9.6 2.9 2.8 7.7 0.2 2.6 2 0 0 2 2 2 0 IlvB leader peptide Pkinase PF00069.20 AIO00763.1 - 3.7e-16 59.0 0.0 8.6e-16 57.8 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AIO00763.1 - 2e-12 46.7 0.0 5.4e-12 45.3 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase DUF912 PF06024.7 AIO00765.1 - 0.012 15.6 0.0 0.022 14.7 0.0 1.4 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Glycos_transf_1 PF00534.15 AIO00766.1 - 1e-10 41.3 0.0 2.7e-10 39.9 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 AIO00766.1 - 1.1e-07 32.1 0.3 4.9e-07 29.9 0.2 2.1 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.1 AIO00766.1 - 5.3e-05 23.4 0.0 0.00019 21.6 0.0 1.9 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_transf_90 PF05686.7 AIO00766.1 - 0.0023 16.6 0.1 0.0065 15.2 0.0 1.6 2 0 0 2 2 2 1 Glycosyl transferase family 90 Peptidase_M20 PF01546.23 AIO00767.1 - 1e-19 70.7 0.0 1.7e-19 70.0 0.0 1.4 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 AIO00767.1 - 5.9e-13 48.5 0.0 1.2e-12 47.5 0.0 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.12 AIO00767.1 - 0.037 13.7 0.0 0.058 13.1 0.0 1.3 1 0 0 1 1 1 0 Peptidase family M28 Ribosomal_L40e PF01020.12 AIO00768.1 - 2.2e-33 113.6 12.1 3.5e-33 112.9 8.4 1.3 1 0 0 1 1 1 1 Ribosomal L40e family ubiquitin PF00240.18 AIO00768.1 - 2.2e-33 113.4 0.3 2.9e-33 113.0 0.2 1.2 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 AIO00768.1 - 7.7e-20 70.3 0.4 1.1e-19 69.8 0.2 1.2 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 AIO00768.1 - 2.4e-05 24.5 0.1 9.4e-05 22.5 0.1 1.8 1 1 0 1 1 1 1 Ubiquitin-like domain Telomere_Sde2 PF13019.1 AIO00768.1 - 0.00046 19.9 0.0 0.00067 19.3 0.0 1.2 1 0 0 1 1 1 1 Telomere stability and silencing Rad60-SLD_2 PF13881.1 AIO00768.1 - 0.016 15.0 0.1 0.03 14.1 0.0 1.6 1 1 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like DUF2870 PF11069.3 AIO00768.1 - 0.071 13.1 0.0 0.15 12.0 0.0 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2870) DUF2407 PF10302.4 AIO00768.1 - 0.079 13.1 0.0 0.094 12.9 0.0 1.3 1 1 0 1 1 1 0 DUF2407 ubiquitin-like domain zf-CHY PF05495.7 AIO00768.1 - 0.099 12.8 3.3 0.15 12.2 2.3 1.2 1 0 0 1 1 1 0 CHY zinc finger RINGv PF12906.2 AIO00770.1 - 2e-11 43.7 5.7 2e-11 43.7 4.0 2.4 2 0 0 2 2 2 1 RING-variant domain Dus PF01207.12 AIO00771.1 - 1.2e-52 178.6 0.4 5e-21 74.8 0.0 4.1 4 0 0 4 4 4 4 Dihydrouridine synthase (Dus) DHO_dh PF01180.16 AIO00771.1 - 0.14 11.0 0.0 0.76 8.6 0.0 1.9 2 0 0 2 2 2 0 Dihydroorotate dehydrogenase Thioredoxin_8 PF13905.1 AIO00774.1 - 1.4e-24 86.0 0.1 2.2e-24 85.4 0.1 1.2 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin PF00085.15 AIO00774.1 - 1.1e-09 37.9 0.0 2.5e-08 33.5 0.0 2.1 2 0 0 2 2 2 1 Thioredoxin Redoxin PF08534.5 AIO00774.1 - 3.1e-09 36.5 0.0 4.1e-09 36.1 0.0 1.1 1 0 0 1 1 1 1 Redoxin Thioredoxin_2 PF13098.1 AIO00774.1 - 4.1e-08 33.4 0.0 5.6e-08 32.9 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin-like domain AhpC-TSA PF00578.16 AIO00774.1 - 5.9e-08 32.4 0.0 7.9e-08 32.0 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_9 PF14595.1 AIO00774.1 - 9.2e-06 25.2 0.0 4.4e-05 23.0 0.0 1.8 2 0 0 2 2 2 1 Thioredoxin TraF PF13728.1 AIO00774.1 - 7.7e-05 22.2 0.0 0.00011 21.7 0.0 1.2 1 0 0 1 1 1 1 F plasmid transfer operon protein Thioredoxin_7 PF13899.1 AIO00774.1 - 0.00047 20.1 0.0 0.00076 19.4 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin-like Glutaredoxin PF00462.19 AIO00774.1 - 0.00088 19.2 0.1 0.02 14.9 0.0 2.3 2 0 0 2 2 2 1 Glutaredoxin DUF953 PF06110.6 AIO00774.1 - 0.042 13.2 0.0 1.7 8.1 0.0 2.1 1 1 0 1 1 1 0 Eukaryotic protein of unknown function (DUF953) DUF3800 PF12686.2 AIO00774.1 - 0.05 13.2 0.0 0.062 12.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3800) Herpes_gp2 PF05955.6 AIO00775.1 - 0.12 11.7 1.6 0.11 11.7 0.4 1.5 2 0 0 2 2 2 0 Equine herpesvirus glycoprotein gp2 Peptidase_M8 PF01457.11 AIO00776.1 - 2e-121 405.9 0.0 4.2e-121 404.8 0.0 1.4 1 1 0 1 1 1 1 Leishmanolysin CRAL_TRIO PF00650.15 AIO00779.1 - 5.5e-45 152.7 0.0 9.1e-45 151.9 0.0 1.4 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.1 AIO00779.1 - 0.00033 20.6 0.0 0.00068 19.5 0.0 1.5 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain YopR_core PF09025.5 AIO00779.1 - 0.027 14.4 0.1 0.06 13.3 0.0 1.5 1 0 0 1 1 1 0 YopR Core Glyco_hydro_1 PF00232.13 AIO00779.1 - 0.077 11.1 0.0 0.12 10.5 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 1 CRAL_TRIO PF00650.15 AIO00780.1 - 2.9e-38 130.8 0.0 4.8e-38 130.1 0.0 1.4 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.1 AIO00780.1 - 0.0042 16.9 0.0 0.016 15.1 0.0 1.9 1 1 0 1 1 1 1 Divergent CRAL/TRIO domain CRAL_TRIO_N PF03765.10 AIO00780.1 - 0.014 15.4 0.0 0.043 13.9 0.0 1.9 1 0 0 1 1 1 0 CRAL/TRIO, N-terminal domain CRAL_TRIO PF00650.15 AIO00781.1 - 5.9e-35 120.1 0.0 9.4e-35 119.4 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.1 AIO00781.1 - 0.00065 19.6 0.0 0.0042 16.9 0.0 2.0 2 0 0 2 2 2 1 Divergent CRAL/TRIO domain UBA PF00627.26 AIO00781.1 - 0.035 13.9 0.0 2.7 7.9 0.0 2.7 2 0 0 2 2 2 0 UBA/TS-N domain CorA PF01544.13 AIO00782.1 - 1.8e-07 30.4 0.5 6e-05 22.2 0.1 2.1 2 0 0 2 2 2 2 CorA-like Mg2+ transporter protein tRNA_lig_CPD PF08302.6 AIO00786.1 - 4.5e-06 26.0 0.0 4.5e-05 22.8 0.0 2.3 2 0 0 2 2 2 1 Fungal tRNA ligase phosphodiesterase domain AAA_33 PF13671.1 AIO00786.1 - 0.0045 16.8 0.0 0.014 15.2 0.0 1.8 1 1 0 1 1 1 1 AAA domain MobB PF03205.9 AIO00786.1 - 0.047 13.3 0.0 0.083 12.5 0.0 1.4 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B ABC_tran PF00005.22 AIO00786.1 - 0.049 13.9 0.0 0.1 12.8 0.0 1.5 1 0 0 1 1 1 0 ABC transporter tRNA_lig_kinase PF08303.6 AIO00786.1 - 0.18 11.6 0.0 0.52 10.1 0.0 1.8 1 1 0 1 1 1 0 tRNA ligase kinase domain Aldo_ket_red PF00248.16 AIO00788.1 - 3.1e-57 193.5 0.0 3.8e-57 193.2 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Ion_trans_N PF08412.5 AIO00788.1 - 0.043 13.1 0.0 0.1 11.9 0.0 1.6 1 0 0 1 1 1 0 Ion transport protein N-terminal DUF1500 PF07389.7 AIO00788.1 - 0.11 12.4 0.0 0.28 11.2 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1500) DUF1389 PF07146.6 AIO00790.1 - 0.072 12.1 0.1 0.13 11.2 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1389) HEAT_2 PF13646.1 AIO00790.1 - 1.3 9.3 19.0 0.11 12.7 4.2 4.9 4 2 2 6 6 6 0 HEAT repeats ECH PF00378.15 AIO00796.1 - 7.1e-47 159.5 0.0 9.1e-47 159.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family Peptidase_S49 PF01343.13 AIO00796.1 - 0.042 13.6 0.3 1.6 8.5 0.0 2.3 2 0 0 2 2 2 0 Peptidase family S49 Peptidase_M1 PF01433.15 AIO00797.1 - 2.1e-14 53.4 0.0 4.1e-08 32.7 0.0 2.2 2 0 0 2 2 2 2 Peptidase family M1 Peptidase_MA_2 PF13485.1 AIO00797.1 - 0.00013 22.0 0.0 0.00024 21.1 0.0 1.4 1 0 0 1 1 1 1 Peptidase MA superfamily DUF3633 PF12315.3 AIO00797.1 - 0.0089 15.3 0.0 0.019 14.2 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3633) AalphaY_MDB PF04611.7 AIO00798.1 - 1.1 9.1 4.4 1.6 8.6 0.1 2.8 3 0 0 3 3 3 0 Mating type protein A alpha Y mating type dependent binding region Arf PF00025.16 AIO00799.1 - 6.9e-75 250.0 0.2 7.9e-75 249.9 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.17 AIO00799.1 - 2.4e-14 53.0 0.0 3e-14 52.7 0.0 1.0 1 0 0 1 1 1 1 Ras family SRPRB PF09439.5 AIO00799.1 - 3.1e-14 52.5 0.0 3.8e-14 52.2 0.0 1.0 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.15 AIO00799.1 - 3.3e-11 42.5 0.3 2.8e-08 32.8 0.0 2.2 1 1 1 2 2 2 2 G-protein alpha subunit Miro PF08477.8 AIO00799.1 - 1.8e-09 38.1 0.0 2.4e-09 37.7 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Gtr1_RagA PF04670.7 AIO00799.1 - 7e-08 31.8 0.0 8.6e-08 31.6 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 AIO00799.1 - 1.6e-05 24.8 0.1 2.5e-05 24.2 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.13 AIO00799.1 - 0.0013 17.8 0.0 0.0015 17.6 0.0 1.2 1 0 0 1 1 1 1 6-phosphofructo-2-kinase GTP_EFTU PF00009.22 AIO00799.1 - 0.0034 16.8 0.1 0.037 13.4 0.0 1.9 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain AAA_33 PF13671.1 AIO00799.1 - 0.0083 16.0 0.2 0.013 15.4 0.1 1.6 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.1 AIO00799.1 - 0.12 12.3 0.4 4.1 7.3 0.0 2.1 1 1 1 2 2 2 0 AAA domain PEMT PF04191.8 AIO00800.1 - 5.2e-28 97.2 1.4 5.2e-28 97.2 1.0 1.9 2 1 1 3 3 3 1 Phospholipid methyltransferase S1-P1_nuclease PF02265.11 AIO00801.1 - 5.1e-60 203.2 0.1 6.3e-60 202.9 0.1 1.1 1 0 0 1 1 1 1 S1/P1 Nuclease TM_helix PF05552.7 AIO00801.1 - 0.14 11.7 2.5 1.1 8.9 0.6 2.6 2 0 0 2 2 2 0 Conserved TM helix SNF2_N PF00176.18 AIO00802.1 - 0.001 17.9 0.0 0.0024 16.7 0.0 1.5 1 1 0 1 1 1 1 SNF2 family N-terminal domain ECH PF00378.15 AIO00803.1 - 1.6e-45 155.1 0.0 2.1e-45 154.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family Peptidase_S49 PF01343.13 AIO00803.1 - 0.025 14.3 0.5 0.94 9.2 0.0 2.2 2 0 0 2 2 2 0 Peptidase family S49 Hydrolase_6 PF13344.1 AIO00804.1 - 3.9e-21 74.8 0.0 8.6e-21 73.7 0.0 1.6 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 AIO00804.1 - 1.5e-14 53.4 0.0 3.5e-14 52.2 0.0 1.6 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.21 AIO00804.1 - 4.1e-06 27.3 0.0 0.037 14.4 0.0 2.5 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase PGP_phosphatase PF09419.5 AIO00804.1 - 0.00011 21.6 0.0 0.00024 20.5 0.0 1.5 2 0 0 2 2 2 1 Mitochondrial PGP phosphatase HAD_2 PF13419.1 AIO00804.1 - 0.00033 20.9 0.0 0.37 10.9 0.0 2.2 2 0 0 2 2 2 2 Haloacid dehalogenase-like hydrolase Mfa2 PF08842.5 AIO00805.1 - 0.18 11.1 0.0 0.42 9.9 0.0 1.5 2 0 0 2 2 2 0 Fimbrillin-A associated anchor proteins Mfa1 and Mfa2 Symplekin_C PF12295.3 AIO00806.1 - 1.2e-10 41.6 0.8 1.5e-08 34.7 0.0 3.0 2 1 0 2 2 2 2 Symplekin tight junction protein C terminal WD40 PF00400.27 AIO00808.1 - 2.4e-06 27.2 0.1 0.97 9.4 0.0 3.8 4 0 0 4 4 4 3 WD domain, G-beta repeat Cation_efflux PF01545.16 AIO00810.1 - 5.8e-54 183.0 14.0 7.3e-54 182.7 9.7 1.1 1 0 0 1 1 1 1 Cation efflux family DUF2946 PF11162.3 AIO00810.1 - 5.8 7.1 8.1 0.28 11.4 0.9 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2946) Lipase_3 PF01764.20 AIO00817.1 - 5.6e-40 136.2 0.0 9.5e-40 135.4 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) DUF2974 PF11187.3 AIO00817.1 - 2.7e-06 26.9 0.3 3.4e-05 23.3 0.2 2.1 1 1 0 1 1 1 1 Protein of unknown function (DUF2974) Abhydrolase_6 PF12697.2 AIO00817.1 - 0.016 15.1 0.0 0.02 14.7 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 AIO00817.1 - 0.045 13.5 0.0 0.058 13.1 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family Esterase PF00756.15 AIO00817.1 - 0.05 13.0 0.1 0.25 10.7 0.0 1.9 2 0 0 2 2 2 0 Putative esterase PGAP1 PF07819.8 AIO00817.1 - 0.16 11.5 0.0 0.44 10.1 0.0 1.7 2 0 0 2 2 2 0 PGAP1-like protein PRK PF00485.13 AIO00818.1 - 4.8e-42 143.7 0.0 5.5e-42 143.5 0.0 1.0 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family AAA_17 PF13207.1 AIO00818.1 - 7.5e-10 39.6 0.0 1.5e-09 38.7 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 AIO00818.1 - 1.4e-08 35.0 0.0 2.5e-08 34.2 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 AIO00818.1 - 0.00014 21.7 0.0 0.00034 20.5 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 AIO00818.1 - 0.0011 18.9 0.0 0.0016 18.4 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain APS_kinase PF01583.15 AIO00818.1 - 0.0032 17.1 0.2 0.69 9.5 0.0 2.3 2 0 0 2 2 2 1 Adenylylsulphate kinase ABC_tran PF00005.22 AIO00818.1 - 0.0043 17.3 0.1 0.0052 17.0 0.0 1.4 1 1 0 1 1 1 1 ABC transporter dNK PF01712.14 AIO00818.1 - 0.011 15.5 0.1 0.016 15.1 0.1 1.3 1 0 0 1 1 1 0 Deoxynucleoside kinase cobW PF02492.14 AIO00818.1 - 0.021 14.2 0.0 0.028 13.8 0.0 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain KAP_NTPase PF07693.9 AIO00818.1 - 0.03 13.2 0.0 0.041 12.8 0.0 1.3 1 1 0 1 1 1 0 KAP family P-loop domain MobB PF03205.9 AIO00818.1 - 0.032 13.9 0.3 0.6 9.8 0.1 2.2 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B RNA_helicase PF00910.17 AIO00818.1 - 0.032 14.4 0.0 0.061 13.5 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_10 PF12846.2 AIO00818.1 - 0.044 13.2 0.0 0.065 12.6 0.0 1.3 1 0 0 1 1 1 0 AAA-like domain AAA_19 PF13245.1 AIO00818.1 - 0.049 13.3 0.5 0.21 11.3 0.0 2.2 3 0 0 3 3 3 0 Part of AAA domain KTI12 PF08433.5 AIO00818.1 - 0.05 12.8 0.1 4.9 6.2 0.0 2.0 2 0 0 2 2 2 0 Chromatin associated protein KTI12 AAA_29 PF13555.1 AIO00818.1 - 0.069 12.6 0.3 0.13 11.7 0.2 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain NTPase_1 PF03266.10 AIO00818.1 - 0.076 12.7 0.0 0.14 11.8 0.0 1.4 1 0 0 1 1 1 0 NTPase NACHT PF05729.7 AIO00818.1 - 0.11 12.1 0.0 0.14 11.8 0.0 1.4 1 0 0 1 1 1 0 NACHT domain DUF2075 PF09848.4 AIO00818.1 - 0.13 11.2 0.0 0.15 11.0 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) DUF258 PF03193.11 AIO00818.1 - 0.16 11.1 0.5 0.31 10.2 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 CoaE PF01121.15 AIO00818.1 - 0.19 11.0 1.3 4 6.8 0.2 2.1 2 0 0 2 2 2 0 Dephospho-CoA kinase Fer2 PF00111.22 AIO00819.1 - 2.3e-11 43.2 1.2 3.3e-11 42.7 0.8 1.3 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer2 PF00111.22 AIO00820.1 - 1.2e-08 34.5 2.4 1.8e-08 34.0 1.7 1.2 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain NifU PF01106.12 AIO00820.1 - 0.15 11.8 1.1 0.27 11.0 0.8 1.4 1 0 0 1 1 1 0 NifU-like domain Fer2 PF00111.22 AIO00821.1 - 2.8e-10 39.7 2.0 4e-10 39.2 1.4 1.2 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer2 PF00111.22 AIO00822.1 - 1e-06 28.4 0.9 1.8e-06 27.5 0.6 1.5 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain RNA_polI_A14 PF08203.6 AIO00826.1 - 0.00048 20.3 0.3 0.15 12.3 0.0 4.0 4 0 0 4 4 4 1 Yeast RNA polymerase I subunit RPA14 NIPSNAP PF07978.8 AIO00826.1 - 0.009 15.9 0.0 0.028 14.4 0.0 1.8 1 0 0 1 1 1 1 NIPSNAP Pex14_N PF04695.8 AIO00828.1 - 0.78 9.7 0.0 0.78 9.7 0.0 4.9 4 1 0 4 4 4 0 Peroxisomal membrane anchor protein (Pex14p) conserved region UCR_hinge PF02320.11 AIO00829.1 - 6.6e-22 77.2 3.4 7.4e-22 77.0 2.3 1.0 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase hinge protein COX6B PF02297.12 AIO00829.1 - 1 9.4 4.3 7 6.7 2.8 1.9 1 1 1 2 2 2 0 Cytochrome oxidase c subunit VIb TerD PF02342.13 AIO00830.1 - 2e-72 242.4 0.1 5.4e-53 179.0 0.0 2.4 2 0 0 2 2 2 2 TerD domain Calreticulin PF00262.13 AIO00831.1 - 1.5e-100 336.3 13.2 2.4e-100 335.7 9.1 1.3 1 0 0 1 1 1 1 Calreticulin family DUF3242 PF11586.3 AIO00831.1 - 0.017 14.6 1.4 0.028 13.9 0.2 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3242) Laminin_G_3 PF13385.1 AIO00831.1 - 0.042 14.0 0.0 0.07 13.3 0.0 1.4 1 0 0 1 1 1 0 Concanavalin A-like lectin/glucanases superfamily YtxC PF08812.6 AIO00831.1 - 0.16 11.4 3.4 0.075 12.5 0.7 1.5 2 0 0 2 2 2 0 YtxC-like family RNA_pol_Rpb1_5 PF04998.12 AIO00832.1 - 1.1e-103 346.3 0.3 1.9e-103 345.5 0.2 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_1 PF04997.7 AIO00832.1 - 1e-92 311.0 0.1 5.3e-92 308.6 0.0 2.1 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_2 PF00623.15 AIO00832.1 - 7.4e-65 217.9 0.2 2.2e-64 216.3 0.2 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_6 PF04992.9 AIO00832.1 - 1.5e-43 148.7 0.6 2.9e-43 147.7 0.4 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 6 RNA_pol_Rpb1_3 PF04983.13 AIO00832.1 - 2.9e-40 137.5 0.0 7e-40 136.3 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.12 AIO00832.1 - 4.1e-29 100.4 0.1 1.3e-28 98.8 0.1 2.0 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 RNA_pol_Rpb1_7 PF04990.7 AIO00832.1 - 1.1e-26 93.1 1.0 3.3e-26 91.6 0.7 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 7 PspA_IM30 PF04012.7 AIO00832.1 - 0.03 13.6 1.9 0.066 12.5 1.3 1.5 1 0 0 1 1 1 0 PspA/IM30 family CRCB PF02537.10 AIO00833.1 - 1.2e-17 63.8 7.8 1e-16 60.8 0.9 2.7 2 1 1 3 3 3 2 CrcB-like protein RskA PF10099.4 AIO00833.1 - 0.036 13.7 4.4 0.1 12.3 0.9 2.1 2 0 0 2 2 2 0 Anti-sigma-K factor rskA Metallophos PF00149.23 AIO00834.1 - 1.2e-42 145.5 0.9 1.6e-42 145.1 0.6 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Pyr_redox_2 PF07992.9 AIO00835.1 - 1.1e-26 93.9 0.0 9e-26 90.9 0.0 3.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.17 AIO00835.1 - 1.2e-17 63.8 0.0 5.3e-17 61.8 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.22 AIO00835.1 - 4.9e-16 58.9 1.3 2.5e-12 47.0 0.0 3.2 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 AIO00835.1 - 2.2e-13 50.7 0.2 9.6e-06 25.8 0.0 3.4 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 AIO00835.1 - 1.7e-09 37.2 1.3 3.7e-09 36.1 0.1 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase DAO PF01266.19 AIO00835.1 - 1.3e-08 34.2 9.2 0.00087 18.2 1.7 4.2 3 1 1 4 4 4 3 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 AIO00835.1 - 2.9e-06 27.2 1.3 0.00065 19.6 0.1 2.8 3 0 0 3 3 2 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.1 AIO00835.1 - 5.2e-06 25.6 0.0 0.00011 21.2 0.0 2.4 2 1 1 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) HI0933_like PF03486.9 AIO00835.1 - 1e-05 24.2 6.9 0.0031 16.0 0.7 3.2 3 0 0 3 3 3 2 HI0933-like protein GIDA PF01134.17 AIO00835.1 - 2.4e-05 23.3 3.0 0.34 9.7 0.0 3.3 2 1 0 2 2 2 2 Glucose inhibited division protein A Thi4 PF01946.12 AIO00835.1 - 4.4e-05 22.6 0.7 0.0039 16.3 0.1 2.4 2 0 0 2 2 2 1 Thi4 family FAD_binding_2 PF00890.19 AIO00835.1 - 6.5e-05 21.9 10.4 0.0006 18.7 1.4 4.0 3 2 1 4 4 4 1 FAD binding domain FAD_binding_3 PF01494.14 AIO00835.1 - 8.1e-05 21.8 4.0 0.0028 16.7 0.4 3.0 2 1 1 3 3 3 1 FAD binding domain ThiF PF00899.16 AIO00835.1 - 0.0003 20.6 0.0 0.0012 18.6 0.0 2.0 2 0 0 2 2 2 1 ThiF family NAD_binding_9 PF13454.1 AIO00835.1 - 0.00032 20.4 2.7 0.72 9.6 0.5 3.8 2 2 1 3 3 3 2 FAD-NAD(P)-binding Lycopene_cycl PF05834.7 AIO00835.1 - 0.0009 18.2 0.9 0.52 9.1 0.2 2.5 2 1 0 2 2 2 2 Lycopene cyclase protein 3HCDH_N PF02737.13 AIO00835.1 - 0.0054 16.3 1.0 0.0089 15.6 0.0 1.8 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain F420_oxidored PF03807.12 AIO00835.1 - 0.0062 16.9 0.3 6.4 7.2 0.1 2.8 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent Shikimate_DH PF01488.15 AIO00835.1 - 0.0068 16.5 0.2 0.022 14.8 0.0 2.0 2 0 0 2 2 1 1 Shikimate / quinate 5-dehydrogenase TrkA_N PF02254.13 AIO00835.1 - 0.052 13.5 0.7 0.4 10.7 0.0 2.5 2 0 0 2 2 2 0 TrkA-N domain Trp_halogenase PF04820.9 AIO00835.1 - 0.43 9.1 2.7 3.1 6.2 0.4 2.2 2 0 0 2 2 2 0 Tryptophan halogenase Pyr_redox_2 PF07992.9 AIO00836.1 - 4.6e-26 91.9 0.0 7e-26 91.3 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.17 AIO00836.1 - 2.3e-20 72.6 0.1 9.6e-20 70.6 0.1 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.22 AIO00836.1 - 3.6e-17 62.5 0.6 2.9e-12 46.8 0.0 3.4 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 AIO00836.1 - 1.5e-11 44.7 0.1 2.3e-07 31.0 0.0 2.3 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 AIO00836.1 - 3.4e-11 42.8 1.3 8.4e-11 41.5 0.0 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase DAO PF01266.19 AIO00836.1 - 1.9e-07 30.3 5.8 3.2e-06 26.3 0.1 3.0 2 1 1 3 3 3 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 AIO00836.1 - 3.6e-07 30.1 4.5 0.00021 21.2 0.3 2.7 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 AIO00836.1 - 1.6e-06 27.3 0.9 0.00025 20.2 0.0 3.0 3 0 0 3 3 3 1 Thi4 family FAD_binding_2 PF00890.19 AIO00836.1 - 2.6e-06 26.5 0.5 2.6e-06 26.5 0.3 2.3 2 0 0 2 2 2 1 FAD binding domain GIDA PF01134.17 AIO00836.1 - 3.9e-06 25.9 2.8 0.00022 20.2 0.4 3.0 2 1 0 2 2 2 1 Glucose inhibited division protein A HI0933_like PF03486.9 AIO00836.1 - 4.2e-06 25.4 4.0 1.2e-05 24.0 0.1 3.1 4 0 0 4 4 4 1 HI0933-like protein Lycopene_cycl PF05834.7 AIO00836.1 - 2.7e-05 23.2 0.1 0.0032 16.4 0.0 2.4 2 0 0 2 2 2 1 Lycopene cyclase protein FAD_binding_3 PF01494.14 AIO00836.1 - 0.00011 21.4 0.9 0.0056 15.7 0.0 2.8 3 0 0 3 3 3 1 FAD binding domain NAD_binding_9 PF13454.1 AIO00836.1 - 0.0063 16.3 0.2 0.19 11.4 0.0 3.0 2 1 0 2 2 2 1 FAD-NAD(P)-binding K_oxygenase PF13434.1 AIO00836.1 - 0.0087 15.0 0.0 0.14 11.0 0.0 2.3 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) ThiF PF00899.16 AIO00836.1 - 0.032 14.0 0.4 0.15 11.8 0.1 2.2 2 0 0 2 2 2 0 ThiF family NAD_binding_7 PF13241.1 AIO00836.1 - 0.14 12.4 0.9 1.2 9.4 0.1 2.8 3 1 0 3 3 3 0 Putative NAD(P)-binding TrkA_N PF02254.13 AIO00836.1 - 0.17 11.8 1.5 12 5.9 0.0 3.1 3 0 0 3 3 3 0 TrkA-N domain Podoplanin PF05808.6 AIO00837.1 - 5 6.6 26.2 12 5.4 18.1 1.7 1 0 0 1 1 1 0 Podoplanin PPR_3 PF13812.1 AIO00838.1 - 0.011 15.8 0.5 12 6.4 0.0 4.5 4 0 0 4 4 4 0 Pentatricopeptide repeat domain PTPLA PF04387.9 AIO00838.1 - 0.039 13.3 0.1 0.089 12.2 0.0 1.5 1 0 0 1 1 1 0 Protein tyrosine phosphatase-like protein, PTPLA PPR PF01535.15 AIO00838.1 - 0.074 13.0 0.2 0.9 9.6 0.0 2.9 3 0 0 3 3 3 0 PPR repeat DNA_pol_A_exo1 PF01612.15 AIO00839.1 - 7.4e-05 22.2 0.0 0.00033 20.1 0.0 2.0 2 0 0 2 2 2 1 3'-5' exonuclease MORN PF02493.15 AIO00840.1 - 1.5e-15 55.9 25.5 0.00018 21.0 1.9 5.5 5 0 0 5 5 5 5 MORN repeat Kinesin PF00225.18 AIO00840.1 - 5.3e-14 51.6 0.0 4.8e-13 48.5 0.0 2.1 1 1 0 1 1 1 1 Kinesin motor domain Bap31 PF05529.7 AIO00841.1 - 0.01 15.3 5.3 0.016 14.6 3.7 1.4 1 1 0 1 1 1 0 B-cell receptor-associated protein 31-like HlyIII PF03006.15 AIO00841.1 - 0.016 14.6 1.8 0.052 12.9 1.5 1.6 2 0 0 2 2 2 0 Haemolysin-III related DUF4131 PF13567.1 AIO00841.1 - 0.23 10.8 1.7 0.36 10.2 1.2 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4131) FtsL PF04999.8 AIO00841.1 - 1 9.1 4.2 1.9 8.2 0.1 2.5 1 1 2 3 3 3 0 Cell division protein FtsL RCC1 PF00415.13 AIO00842.1 - 1.7e-22 79.3 18.7 1.5e-10 41.1 0.0 7.5 6 2 0 6 6 6 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 AIO00842.1 - 9e-18 63.4 15.7 2.1e-05 24.0 1.2 5.2 5 0 0 5 5 5 4 Regulator of chromosome condensation (RCC1) repeat EMP24_GP25L PF01105.19 AIO00843.1 - 1.8e-28 99.5 0.0 2.6e-28 99.0 0.0 1.2 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD COPIIcoated_ERV PF07970.7 AIO00844.1 - 6.5e-66 222.1 0.0 1.1e-65 221.3 0.0 1.4 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.1 AIO00844.1 - 4.1e-30 103.6 0.3 1.1e-29 102.2 0.2 1.7 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) RRM_1 PF00076.17 AIO00847.1 - 1.5e-11 43.7 0.0 3.2e-11 42.6 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 AIO00847.1 - 0.0015 18.5 0.0 0.0031 17.4 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 AIO00847.1 - 0.0015 18.3 0.0 0.0029 17.4 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF4501 PF14946.1 AIO00848.1 - 9.1 5.7 8.3 58 3.0 4.4 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4501) Arf PF00025.16 AIO00849.1 - 6.1e-78 260.0 0.1 6.7e-78 259.9 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 AIO00849.1 - 1.9e-14 53.3 0.0 2.3e-14 53.0 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.17 AIO00849.1 - 4.3e-13 48.9 0.0 4.7e-13 48.8 0.0 1.1 1 0 0 1 1 1 1 Ras family G-alpha PF00503.15 AIO00849.1 - 5.3e-13 48.4 0.4 2e-09 36.6 0.0 2.2 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.7 AIO00849.1 - 8.3e-10 38.1 0.0 1e-09 37.9 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 AIO00849.1 - 2.6e-08 34.3 0.0 3.4e-08 33.9 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 AIO00849.1 - 4.9e-05 23.2 0.0 6.5e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.13 AIO00849.1 - 0.007 15.4 0.0 0.0089 15.1 0.0 1.3 1 0 0 1 1 1 1 6-phosphofructo-2-kinase GTP_EFTU PF00009.22 AIO00849.1 - 0.016 14.6 0.1 0.18 11.2 0.0 1.9 1 1 1 2 2 2 0 Elongation factor Tu GTP binding domain AAA_33 PF13671.1 AIO00849.1 - 0.031 14.1 0.1 0.051 13.4 0.1 1.6 1 1 0 1 1 1 0 AAA domain DUF1771 PF08590.5 AIO00851.1 - 1.6e-17 63.2 2.7 3.4e-17 62.2 1.9 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1771) Smr PF01713.16 AIO00851.1 - 6.1e-12 45.5 0.0 1.5e-11 44.3 0.0 1.7 1 0 0 1 1 1 1 Smr domain KH_1 PF00013.24 AIO00851.1 - 3e-09 36.3 0.4 5.6e-09 35.5 0.3 1.5 1 0 0 1 1 1 1 KH domain KH_3 PF13014.1 AIO00851.1 - 1.1e-06 28.1 0.0 2.1e-06 27.2 0.0 1.5 1 0 0 1 1 1 1 KH domain KH_2 PF07650.12 AIO00851.1 - 0.013 14.9 0.2 0.032 13.7 0.1 1.7 1 0 0 1 1 1 0 KH domain SLS PF14611.1 AIO00851.1 - 0.027 13.8 0.0 0.039 13.3 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial inner-membrane-bound regulator Maf1 PF09174.5 AIO00852.1 - 4.4e-43 147.1 0.0 5.3e-43 146.9 0.0 1.1 1 0 0 1 1 1 1 Maf1 regulator Tryp_alpha_amyl PF00234.17 AIO00852.1 - 0.0082 16.3 0.0 0.013 15.6 0.0 1.3 1 0 0 1 1 1 1 Protease inhibitor/seed storage/LTP family HD_assoc PF13286.1 AIO00853.1 - 0.054 13.7 0.2 0.13 12.5 0.1 1.6 1 0 0 1 1 1 0 Phosphohydrolase-associated domain EmrE PF13536.1 AIO00854.1 - 0.019 15.1 4.5 0.019 15.1 3.1 2.4 3 0 0 3 3 3 0 Multidrug resistance efflux transporter DUF948 PF06103.6 AIO00854.1 - 0.041 13.7 0.1 0.13 12.1 0.0 1.9 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) SKG6 PF08693.5 AIO00854.1 - 0.08 12.2 1.4 0.2 11.0 1.0 1.6 1 0 0 1 1 1 0 Transmembrane alpha-helix domain EcsB PF05975.7 AIO00854.1 - 0.32 9.4 7.8 0.49 8.8 5.4 1.2 1 0 0 1 1 1 0 Bacterial ABC transporter protein EcsB DUF1049 PF06305.6 AIO00854.1 - 9.5 5.7 7.6 0.21 11.0 0.3 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1049) Ribosomal_L12 PF00542.14 AIO00855.1 - 1.6e-17 63.2 2.2 2.8e-17 62.4 1.5 1.4 1 0 0 1 1 1 1 Ribosomal protein L7/L12 C-terminal domain T2SM PF04612.7 AIO00855.1 - 0.11 12.2 0.0 0.18 11.6 0.0 1.4 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein M Pkinase PF00069.20 AIO00856.1 - 6.6e-56 189.3 0.0 1.5e-55 188.1 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 AIO00856.1 - 4e-29 101.4 0.0 8.5e-29 100.4 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase RIO1 PF01163.17 AIO00856.1 - 0.0027 17.0 0.2 0.011 15.1 0.1 2.0 1 1 0 1 1 1 1 RIO1 family Pox_ser-thr_kin PF05445.6 AIO00856.1 - 0.016 14.0 0.1 0.025 13.3 0.1 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase L71 PF02448.10 AIO00856.1 - 0.038 13.8 0.1 0.096 12.5 0.1 1.7 1 0 0 1 1 1 0 L71 family Bap31 PF05529.7 AIO00856.1 - 2.3 7.6 5.8 9.6 5.6 0.0 2.3 2 0 0 2 2 2 0 B-cell receptor-associated protein 31-like Spc7 PF08317.6 AIO00856.1 - 3.5 6.1 10.9 0.089 11.4 0.2 2.1 2 0 0 2 2 2 0 Spc7 kinetochore protein DivIC PF04977.10 AIO00856.1 - 6.7 6.2 10.0 1.7 8.1 0.0 3.1 3 0 0 3 3 3 0 Septum formation initiator Aldo_ket_red PF00248.16 AIO00858.1 - 1.1e-63 214.6 0.0 1.3e-63 214.4 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family PSII PF00421.14 AIO00858.1 - 0.073 11.6 0.0 0.075 11.6 0.0 1.2 1 0 0 1 1 1 0 Photosystem II protein Clathrin PF00637.15 AIO00859.1 - 6.9e-09 35.4 5.5 1.5e-08 34.3 0.3 2.8 3 0 0 3 3 3 1 Region in Clathrin and VPS zf-Apc11 PF12861.2 AIO00859.1 - 0.084 12.7 2.6 0.26 11.1 1.8 1.8 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.2 AIO00859.1 - 0.81 9.8 7.4 2.2 8.4 5.1 1.7 1 0 0 1 1 1 0 RING-H2 zinc finger zf-RING_2 PF13639.1 AIO00859.1 - 1.5 8.7 12.4 1.2 9.0 6.9 2.3 2 0 0 2 2 2 0 Ring finger domain zf-RING_5 PF14634.1 AIO00859.1 - 1.5 8.5 15.7 0.63 9.8 7.6 2.4 2 0 0 2 2 2 0 zinc-RING finger domain zf-C3HC4_2 PF13923.1 AIO00859.1 - 2.1 8.4 11.6 0.69 9.9 5.1 2.5 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Nup54 PF13874.1 AIO00860.1 - 1.5e-35 121.9 0.7 1.5e-35 121.9 0.5 1.7 2 0 0 2 2 2 1 Nucleoporin complex subunit 54 RIIa PF02197.12 AIO00861.1 - 0.038 13.4 0.2 0.059 12.8 0.1 1.3 1 0 0 1 1 1 0 Regulatory subunit of type II PKA R-subunit DUF4588 PF15251.1 AIO00862.1 - 0.00099 19.1 1.6 0.0024 17.8 1.1 1.8 1 1 0 1 1 1 1 Domain of unknown function (DUF4588) Herpes_glycop_H PF02489.11 AIO00862.1 - 0.014 13.4 0.1 0.02 12.9 0.1 1.1 1 0 0 1 1 1 0 Herpesvirus glycoprotein H Inositol_P PF00459.20 AIO00863.1 - 7.1e-19 68.1 0.0 7.6e-18 64.7 0.0 2.3 1 1 0 1 1 1 1 Inositol monophosphatase family SQS_PSY PF00494.14 AIO00865.1 - 3.7e-45 154.3 0.3 6.2e-45 153.5 0.1 1.4 2 0 0 2 2 2 1 Squalene/phytoene synthase bPH_2 PF03703.9 AIO00865.1 - 0.15 12.1 0.0 0.3 11.1 0.0 1.5 1 0 0 1 1 1 0 Bacterial PH domain NUDIX PF00293.23 AIO00866.1 - 2.9e-14 52.8 0.1 4.8e-14 52.1 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain zf-NADH-PPase PF09297.6 AIO00866.1 - 1.3e-07 31.0 4.3 2.2e-07 30.2 3.0 1.4 1 0 0 1 1 1 1 NADH pyrophosphatase zinc ribbon domain DZR PF12773.2 AIO00866.1 - 0.00095 18.9 0.7 0.0018 18.0 0.5 1.4 1 0 0 1 1 1 1 Double zinc ribbon HypA PF01155.14 AIO00866.1 - 0.025 14.2 1.0 0.5 10.0 0.2 2.3 2 0 0 2 2 2 0 Hydrogenase expression/synthesis hypA family NUDIX-like PF09296.6 AIO00866.1 - 0.085 13.2 0.0 0.18 12.2 0.0 1.5 1 0 0 1 1 1 0 NADH pyrophosphatase-like rudimentary NUDIX domain zf-C4pol PF14260.1 AIO00866.1 - 0.11 12.4 0.2 0.22 11.5 0.2 1.5 1 0 0 1 1 1 0 C4-type zinc-finger of DNA polymerase delta zinc_ribbon_2 PF13240.1 AIO00866.1 - 0.2 11.1 3.3 0.65 9.5 0.4 2.3 2 0 0 2 2 2 0 zinc-ribbon domain UPF0547 PF10571.4 AIO00866.1 - 0.43 10.3 3.9 6.7 6.5 0.1 2.4 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 zf-ribbon_3 PF13248.1 AIO00866.1 - 0.65 9.2 6.6 0.13 11.4 0.7 2.0 1 1 0 2 2 2 0 zinc-ribbon domain Pkinase PF00069.20 AIO00867.1 - 1.2e-62 211.4 0.0 1.6e-62 211.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AIO00867.1 - 1.1e-43 149.2 0.0 1.6e-43 148.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 AIO00867.1 - 1.4e-08 34.0 0.0 4.2e-07 29.2 0.0 2.2 2 0 0 2 2 2 1 Kinase-like PH PF00169.24 AIO00867.1 - 2.9e-05 24.2 0.0 6.4e-05 23.0 0.0 1.6 1 0 0 1 1 1 1 PH domain RIO1 PF01163.17 AIO00867.1 - 0.044 13.1 0.0 0.07 12.4 0.0 1.2 1 0 0 1 1 1 0 RIO1 family PH_9 PF15410.1 AIO00867.1 - 0.15 12.1 0.1 0.41 10.8 0.1 1.7 1 1 0 1 1 1 0 Pleckstrin homology domain Carboxyl_trans PF01039.17 AIO00868.1 - 9e-123 410.2 0.0 1.2e-122 409.7 0.0 1.2 1 0 0 1 1 1 1 Carboxyl transferase domain ACC_central PF08326.7 AIO00868.1 - 1.3e-110 370.6 0.0 1.9e-107 360.2 0.0 2.3 1 1 0 1 1 1 1 Acetyl-CoA carboxylase, central region CPSase_L_D2 PF02786.12 AIO00868.1 - 9.3e-52 175.3 0.0 1.7e-51 174.5 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_chain PF00289.17 AIO00868.1 - 3.7e-24 84.9 0.0 1.6e-23 82.9 0.0 2.1 2 0 0 2 2 2 1 Carbamoyl-phosphate synthase L chain, N-terminal domain Biotin_carb_C PF02785.14 AIO00868.1 - 6e-21 74.4 0.0 3.2e-20 72.1 0.0 2.3 2 0 0 2 2 2 1 Biotin carboxylase C-terminal domain ATP-grasp_4 PF13535.1 AIO00868.1 - 2e-12 47.2 0.0 4.3e-12 46.1 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain ATPgrasp_Ter PF15632.1 AIO00868.1 - 5.6e-12 45.0 0.0 3.4e-06 26.0 0.0 3.1 2 1 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon Biotin_lipoyl PF00364.17 AIO00868.1 - 1.8e-07 30.6 0.0 4.5e-07 29.4 0.0 1.7 1 0 0 1 1 1 1 Biotin-requiring enzyme Dala_Dala_lig_C PF07478.8 AIO00868.1 - 9.1e-05 21.9 0.0 0.00022 20.6 0.0 1.6 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.17 AIO00868.1 - 0.00065 19.0 0.0 0.0016 17.8 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_3 PF02655.9 AIO00868.1 - 0.05 13.4 0.0 0.12 12.2 0.0 1.6 1 0 0 1 1 1 0 ATP-grasp domain DUF3077 PF11275.3 AIO00868.1 - 0.11 12.5 0.1 0.59 10.1 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3077) RimK PF08443.6 AIO00868.1 - 0.35 10.3 0.0 4 6.8 0.0 2.2 2 0 0 2 2 2 0 RimK-like ATP-grasp domain SMK-1 PF04802.10 AIO00869.1 - 3e-06 26.8 0.0 5.4e-06 26.0 0.0 1.3 1 0 0 1 1 1 1 Component of IIS longevity pathway SMK-1 Bacillus_HBL PF05791.6 AIO00871.1 - 0.024 14.0 0.1 0.11 11.8 0.0 2.0 1 1 1 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) ASL_C PF08328.6 AIO00871.1 - 0.11 12.3 1.2 0.39 10.5 0.3 2.2 2 0 0 2 2 2 0 Adenylosuccinate lyase C-terminal BCAS2 PF05700.6 AIO00871.1 - 0.16 11.3 13.0 0.13 11.7 6.6 1.9 1 1 1 2 2 2 0 Breast carcinoma amplified sequence 2 (BCAS2) DUF724 PF05266.9 AIO00871.1 - 0.58 9.7 7.9 0.45 10.1 4.2 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF724) Syntaxin-6_N PF09177.6 AIO00871.1 - 0.77 10.2 5.9 0.22 11.9 0.9 2.5 2 1 1 3 3 3 0 Syntaxin 6, N-terminal Spc7 PF08317.6 AIO00871.1 - 1.9 7.0 9.9 5.6 5.5 6.9 1.6 1 1 0 1 1 1 0 Spc7 kinetochore protein DUF3123 PF11321.3 AIO00871.1 - 2.7 8.3 11.0 5.1 7.4 3.0 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF3123) DUF883 PF05957.8 AIO00871.1 - 7.4 7.0 23.3 1.1 9.7 5.8 3.7 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF883) DUF948 PF06103.6 AIO00874.1 - 0.037 13.8 0.1 0.071 12.9 0.1 1.6 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) DUF4111 PF13427.1 AIO00874.1 - 0.09 12.6 1.7 0.15 11.9 1.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4111) DUF1515 PF07439.6 AIO00874.1 - 0.29 10.9 1.9 4.7 7.0 0.4 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1515) Phg_2220_C PF09524.5 AIO00874.1 - 0.64 10.0 2.6 8.8 6.4 0.1 2.3 1 1 1 2 2 2 0 Conserved phage C-terminus (Phg_2220_C) Cyclase PF04199.8 AIO00875.1 - 4.5e-18 65.5 0.0 6.4e-18 65.0 0.0 1.2 1 0 0 1 1 1 1 Putative cyclase Zip PF02535.17 AIO00876.1 - 3.1e-39 134.8 9.8 3.7e-39 134.6 6.8 1.0 1 0 0 1 1 1 1 ZIP Zinc transporter Zip PF02535.17 AIO00877.1 - 6.6e-24 84.4 2.1 7.7e-24 84.2 1.4 1.0 1 0 0 1 1 1 1 ZIP Zinc transporter BTB_2 PF02214.17 AIO00878.1 - 7.4e-05 22.8 0.0 0.00025 21.1 0.0 1.9 1 1 0 1 1 1 1 BTB/POZ domain SPRY PF00622.23 AIO00878.1 - 0.00029 20.9 0.0 0.0099 15.9 0.0 2.6 2 1 1 3 3 3 1 SPRY domain Peptidase_M16 PF00675.15 AIO00879.1 - 3.5e-32 111.2 0.0 7.4e-32 110.1 0.0 1.6 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 AIO00879.1 - 4.8e-13 49.1 0.0 4.1e-08 33.1 0.0 2.6 2 0 0 2 2 2 2 Peptidase M16 inactive domain Nop14 PF04147.7 AIO00879.1 - 0.064 11.1 4.8 0.12 10.3 3.3 1.3 1 0 0 1 1 1 0 Nop14-like family Sigma70_ner PF04546.8 AIO00879.1 - 0.11 12.1 6.2 2.4 7.7 4.8 2.2 2 0 0 2 2 2 0 Sigma-70, non-essential region CDC45 PF02724.9 AIO00879.1 - 0.27 9.2 2.7 0.42 8.5 1.9 1.2 1 0 0 1 1 1 0 CDC45-like protein CobT PF06213.7 AIO00879.1 - 0.37 9.8 10.7 0.62 9.1 7.4 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT DnaJ PF00226.26 AIO00880.1 - 4.4e-19 67.9 0.0 6.9e-19 67.3 0.0 1.3 1 0 0 1 1 1 1 DnaJ domain DUF2935 PF11155.3 AIO00882.1 - 0.87 9.6 11.0 0.99 9.4 3.4 3.2 2 0 0 2 2 2 0 Domain of unknown function (DUF2935) PEMT PF04191.8 AIO00883.1 - 2.2e-49 165.9 16.1 1.8e-28 98.7 0.6 3.1 3 0 0 3 3 3 2 Phospholipid methyltransferase CPSase_L_D2 PF02786.12 AIO00884.1 - 8.9e-62 208.1 0.0 1.6e-61 207.3 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_chain PF00289.17 AIO00884.1 - 3.8e-41 139.6 0.0 1e-40 138.2 0.0 1.8 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain Biotin_carb_C PF02785.14 AIO00884.1 - 1.8e-33 114.6 0.0 4.2e-33 113.5 0.0 1.7 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain ATP-grasp_4 PF13535.1 AIO00884.1 - 4.1e-15 55.9 0.5 9.2e-15 54.8 0.1 1.7 2 0 0 2 2 2 1 ATP-grasp domain Biotin_lipoyl PF00364.17 AIO00884.1 - 1.2e-14 53.6 0.3 3e-14 52.4 0.2 1.7 1 0 0 1 1 1 1 Biotin-requiring enzyme Dala_Dala_lig_C PF07478.8 AIO00884.1 - 1e-11 44.6 0.0 2.6e-11 43.2 0.0 1.6 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus ATPgrasp_Ter PF15632.1 AIO00884.1 - 6.5e-11 41.5 0.0 2.1e-07 29.9 0.0 2.1 2 0 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp PF02222.17 AIO00884.1 - 2.4e-09 36.7 0.0 4.2e-09 35.9 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain Biotin_lipoyl_2 PF13533.1 AIO00884.1 - 2.5e-07 30.2 0.1 2.6e-06 26.9 0.0 2.3 1 1 1 2 2 2 1 Biotin-lipoyl like HlyD_2 PF12700.2 AIO00884.1 - 0.0021 17.2 0.0 0.2 10.8 0.0 2.2 1 1 1 2 2 2 1 HlyD family secretion protein RimK PF08443.6 AIO00884.1 - 0.0023 17.4 0.0 1.7 8.1 0.0 2.3 2 0 0 2 2 2 2 RimK-like ATP-grasp domain ATP-grasp_3 PF02655.9 AIO00884.1 - 0.0024 17.7 0.0 0.0051 16.6 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain UPF0150 PF03681.10 AIO00884.1 - 0.058 13.0 0.0 0.18 11.4 0.0 1.8 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0150) HlyD_3 PF13437.1 AIO00884.1 - 0.062 13.6 0.1 11 6.4 0.0 2.8 3 0 0 3 3 3 0 HlyD family secretion protein Robl_LC7 PF03259.12 AIO00886.1 - 3.1e-06 26.6 0.0 4.7e-06 26.0 0.0 1.3 1 1 0 1 1 1 1 Roadblock/LC7 domain Thioredoxin PF00085.15 AIO00887.1 - 0.022 14.4 1.4 0.053 13.2 1.0 1.6 1 0 0 1 1 1 0 Thioredoxin PQQ_3 PF13570.1 AIO00887.1 - 0.37 11.1 5.6 26 5.2 0.0 4.7 4 0 0 4 4 4 0 PQQ-like domain UPF0184 PF03670.8 AIO00887.1 - 0.44 10.7 2.8 1.5 9.0 1.9 1.9 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0184) Pkinase PF00069.20 AIO00888.1 - 6.2e-62 209.1 0.0 8.1e-62 208.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AIO00888.1 - 1.3e-41 142.3 0.0 1.8e-41 141.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase PH PF00169.24 AIO00888.1 - 1.3e-10 41.3 0.0 2.5e-10 40.4 0.0 1.4 1 0 0 1 1 1 1 PH domain Kinase-like PF14531.1 AIO00888.1 - 4.7e-09 35.6 0.0 7.5e-09 34.9 0.0 1.3 1 0 0 1 1 1 1 Kinase-like PH_9 PF15410.1 AIO00888.1 - 6.8e-08 32.6 0.4 1.9e-06 28.0 0.3 2.5 1 1 0 1 1 1 1 Pleckstrin homology domain PH_11 PF15413.1 AIO00888.1 - 0.00018 21.6 1.2 0.13 12.5 0.0 2.6 1 1 1 2 2 2 2 Pleckstrin homology domain MFS_1 PF07690.11 AIO00889.1 - 7.3e-18 64.3 22.5 7.3e-18 64.3 15.6 2.4 1 1 0 2 2 2 2 Major Facilitator Superfamily Nodulin-like PF06813.8 AIO00889.1 - 6.6e-07 28.8 24.3 6.6e-07 28.8 16.8 3.2 2 2 1 3 3 3 1 Nodulin-like Histone PF00125.19 AIO00890.1 - 5.9e-13 48.7 0.5 7.2e-13 48.4 0.4 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 AIO00890.1 - 0.00045 20.2 0.4 0.00062 19.7 0.0 1.4 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TAF PF02969.12 AIO00890.1 - 0.00092 19.1 0.1 0.0015 18.4 0.1 1.4 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) Bromo_TP PF07524.8 AIO00890.1 - 0.0034 17.0 0.0 0.0042 16.7 0.0 1.2 1 0 0 1 1 1 1 Bromodomain associated TFIID-31kDa PF02291.10 AIO00890.1 - 0.0048 16.6 0.0 0.0048 16.6 0.0 1.2 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit DUF2205 PF10224.4 AIO00892.1 - 2.8 7.5 15.0 0.76 9.3 0.3 3.9 3 1 1 4 4 4 0 Predicted coiled-coil protein (DUF2205) zf-CCCH PF00642.19 AIO00893.1 - 0.01 15.5 0.4 0.01 15.5 0.3 2.2 3 0 0 3 3 3 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH PF00642.19 AIO00894.1 - 0.011 15.4 1.4 0.011 15.4 0.9 1.8 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) WD40 PF00400.27 AIO00895.1 - 4.2e-36 121.5 6.3 2.5e-08 33.5 0.0 6.4 6 0 0 6 6 6 6 WD domain, G-beta repeat SNARE PF05739.14 AIO00897.1 - 6.4e-13 48.1 8.4 9e-13 47.7 1.0 3.2 3 0 0 3 3 3 1 SNARE domain DUF1640 PF07798.6 AIO00897.1 - 0.0046 17.0 3.5 0.04 13.9 2.5 2.1 1 1 0 1 1 1 1 Protein of unknown function (DUF1640) DUF4208 PF13907.1 AIO00897.1 - 0.032 14.4 1.1 2.3 8.4 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4208) Baculo_PEP_C PF04513.7 AIO00897.1 - 0.039 13.7 5.3 3.3 7.5 0.1 3.1 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus SF-assemblin PF06705.6 AIO00897.1 - 0.15 11.2 5.6 1.1 8.3 0.1 2.2 1 1 1 2 2 2 0 SF-assemblin/beta giardin DUF3154 PF11351.3 AIO00897.1 - 0.32 10.7 4.4 2.7 7.7 0.1 2.8 1 1 1 2 2 2 0 Protein of unknown function (DUF3154) DUF883 PF05957.8 AIO00897.1 - 2.9 8.3 8.2 0.59 10.5 0.4 2.9 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF883) Syntaxin PF00804.20 AIO00897.1 - 3.9 7.7 9.6 0.67 10.1 0.9 3.0 1 1 1 2 2 2 0 Syntaxin NMT_C PF02799.10 AIO00898.1 - 1.2e-70 236.7 0.0 1.9e-70 236.1 0.0 1.3 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, C-terminal domain NMT PF01233.14 AIO00898.1 - 5.5e-62 208.1 0.8 1.5e-59 200.2 0.5 2.3 1 1 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain ERCC4 PF02732.10 AIO00898.1 - 0.1 12.3 0.0 0.19 11.5 0.0 1.3 1 0 0 1 1 1 0 ERCC4 domain NIF PF03031.13 AIO00900.1 - 2.2e-25 89.1 0.0 2.4e-25 89.0 0.0 1.1 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Mito_carr PF00153.22 AIO00901.1 - 7.8e-41 137.6 7.8 1.8e-14 53.1 0.0 4.3 3 2 0 3 3 3 3 Mitochondrial carrier protein Pkinase PF00069.20 AIO00902.1 - 7.6e-59 198.9 0.0 1e-58 198.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AIO00902.1 - 5.4e-27 94.4 0.0 7.7e-27 93.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 AIO00902.1 - 7.4e-05 21.8 0.0 0.00014 20.8 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 AIO00902.1 - 0.0014 17.7 0.0 0.0022 17.0 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Skp1 PF01466.14 AIO00903.1 - 0.045 13.7 0.1 0.08 12.9 0.1 1.4 1 0 0 1 1 1 0 Skp1 family, dimerisation domain Arm PF00514.18 AIO00904.1 - 6e-42 140.0 26.0 8.9e-08 31.6 0.0 16.4 15 2 1 16 16 16 9 Armadillo/beta-catenin-like repeat Arm_2 PF04826.8 AIO00904.1 - 1e-10 41.1 2.4 0.0047 16.0 0.0 6.6 4 2 6 10 10 10 2 Armadillo-like HEAT_2 PF13646.1 AIO00904.1 - 7.6e-05 22.9 6.9 1.6 9.0 0.0 6.3 4 1 3 7 7 7 3 HEAT repeats Atx10homo_assoc PF09759.4 AIO00904.1 - 0.0063 16.2 1.8 12 5.7 0.0 5.5 6 0 0 6 6 6 1 Spinocerebellar ataxia type 10 protein domain HEAT PF02985.17 AIO00904.1 - 3.3 8.0 14.4 17 5.8 0.1 6.3 7 1 0 7 7 7 0 HEAT repeat Utp14 PF04615.8 AIO00905.1 - 5.4e-79 266.2 35.8 2.8e-78 263.8 24.1 2.4 1 1 0 1 1 1 1 Utp14 protein DUF1079 PF06435.6 AIO00907.1 - 0.025 14.5 0.1 0.04 13.8 0.1 1.3 1 0 0 1 1 1 0 Repeat of unknown function (DUF1079) DUF1233 PF06806.7 AIO00907.1 - 0.14 11.7 0.0 0.19 11.2 0.0 1.3 1 0 0 1 1 1 0 Putative excisionase (DUF1233) LRR_9 PF14580.1 AIO00908.1 - 3.2e-16 59.3 0.9 7.5e-16 58.1 0.6 1.6 1 1 0 1 1 1 1 Leucine-rich repeat LRR_4 PF12799.2 AIO00908.1 - 0.0022 17.5 2.7 0.15 11.7 0.0 3.4 3 2 0 3 3 3 1 Leucine Rich repeats (2 copies) CCDC-167 PF15188.1 AIO00908.1 - 0.02 14.8 1.5 0.02 14.8 1.0 2.3 3 0 0 3 3 3 0 Coiled-coil domain-containing protein 167 GvpG PF05120.7 AIO00908.1 - 0.061 13.1 2.0 0.12 12.2 1.4 1.5 1 0 0 1 1 1 0 Gas vesicle protein G HSP70 PF00012.15 AIO00910.1 - 1.1e-06 26.9 0.0 0.0027 15.7 0.0 2.5 3 0 0 3 3 3 2 Hsp70 protein Filament PF00038.16 AIO00911.1 - 0.12 11.8 14.9 1.1 8.6 10.3 2.5 1 1 0 1 1 1 0 Intermediate filament protein NPV_P10 PF05531.7 AIO00911.1 - 2.2 8.5 6.9 9.1 6.6 0.0 4.1 5 0 0 5 5 5 0 Nucleopolyhedrovirus P10 protein Rtt106 PF08512.7 AIO00912.1 - 4.2e-16 58.6 0.0 4.3e-15 55.4 0.0 2.5 3 0 0 3 3 3 1 Histone chaperone Rttp106-like SSrecog PF03531.9 AIO00912.1 - 1.8e-06 27.4 0.0 0.0015 17.9 0.0 2.7 1 1 0 1 1 1 1 Structure-specific recognition protein (SSRP1) CDC45 PF02724.9 AIO00912.1 - 0.0038 15.3 23.1 0.0054 14.8 16.0 1.2 1 0 0 1 1 1 1 CDC45-like protein Nop14 PF04147.7 AIO00912.1 - 0.021 12.7 25.4 0.029 12.3 17.6 1.1 1 0 0 1 1 1 0 Nop14-like family Nop53 PF07767.6 AIO00912.1 - 0.12 11.3 29.9 0.24 10.3 20.7 1.5 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) YL1 PF05764.8 AIO00912.1 - 0.46 10.0 34.7 0.63 9.6 24.1 1.1 1 0 0 1 1 1 0 YL1 nuclear protein Glypican PF01153.14 AIO00912.1 - 1.1 7.7 14.5 1.6 7.2 10.0 1.1 1 0 0 1 1 1 0 Glypican Apt1 PF10351.4 AIO00912.1 - 1.9 7.2 19.1 2.6 6.8 13.2 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain RNA_polI_A34 PF08208.6 AIO00912.1 - 2.6 7.6 37.1 5.7 6.5 25.7 1.5 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 Spt5_N PF11942.3 AIO00912.1 - 3.1 8.4 34.1 7.8 7.1 23.6 1.7 1 0 0 1 1 1 0 Spt5 transcription elongation factor, acidic N-terminal Herpes_DNAp_acc PF04929.7 AIO00912.1 - 3.4 6.5 17.6 5.4 5.8 12.2 1.2 1 0 0 1 1 1 0 Herpes DNA replication accessory factor Dynein_light PF01221.13 AIO00914.1 - 4.1e-43 145.2 1.0 4.8e-43 145.0 0.7 1.0 1 0 0 1 1 1 1 Dynein light chain type 1 Peptidase_C3 PF00548.15 AIO00914.1 - 0.00057 19.7 0.1 0.00059 19.6 0.0 1.1 1 0 0 1 1 1 1 3C cysteine protease (picornain 3C) HTH_33 PF13592.1 AIO00914.1 - 0.051 13.1 0.0 0.091 12.3 0.0 1.4 1 0 0 1 1 1 0 Winged helix-turn helix Imm28 PF15574.1 AIO00914.1 - 0.052 13.1 0.1 0.07 12.7 0.1 1.1 1 0 0 1 1 1 0 Immunity protein 28 Ectatomin PF06457.6 AIO00914.1 - 0.054 13.1 0.0 0.096 12.4 0.0 1.4 1 0 0 1 1 1 0 Ectatomin ECSIT PF06239.6 AIO00914.1 - 0.092 11.5 0.1 0.11 11.2 0.0 1.1 1 0 0 1 1 1 0 Evolutionarily conserved signalling intermediate in Toll pathway LRR_1 PF00560.28 AIO00915.1 - 0.1 12.7 6.3 6.1 7.2 0.3 4.7 4 0 0 4 4 4 0 Leucine Rich Repeat LRR_4 PF12799.2 AIO00915.1 - 0.16 11.6 0.9 10 5.9 0.1 3.9 6 0 0 6 6 6 0 Leucine Rich repeats (2 copies) AAA_13 PF13166.1 AIO00915.1 - 0.17 10.3 0.3 0.25 9.7 0.2 1.1 1 0 0 1 1 1 0 AAA domain DUF334 PF03904.8 AIO00915.1 - 0.39 10.0 0.8 0.62 9.3 0.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF334) Spc7 PF08317.6 AIO00915.1 - 0.7 8.5 5.4 1.3 7.6 3.8 1.4 1 0 0 1 1 1 0 Spc7 kinetochore protein LRR_6 PF13516.1 AIO00915.1 - 0.86 9.8 6.3 33 4.9 0.2 4.9 5 0 0 5 5 5 0 Leucine Rich repeat LRR_8 PF13855.1 AIO00915.1 - 1.8 8.3 4.1 8.5 6.2 0.1 3.5 4 0 0 4 4 4 0 Leucine rich repeat Atg14 PF10186.4 AIO00915.1 - 1.9 7.3 14.6 5.8 5.7 10.2 1.7 1 1 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Cluap1 PF10234.4 AIO00915.1 - 4.4 6.4 12.1 0.56 9.3 4.6 2.0 1 1 1 2 2 2 0 Clusterin-associated protein-1 Pkinase PF00069.20 AIO00917.1 - 1.2e-70 237.6 0.0 2.7e-70 236.5 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AIO00917.1 - 5.6e-52 176.3 0.1 8.8e-52 175.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 AIO00917.1 - 2.7e-06 26.5 0.0 6e-06 25.4 0.0 1.5 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.17 AIO00917.1 - 0.013 14.8 0.1 0.034 13.4 0.1 1.6 1 0 0 1 1 1 0 RIO1 family LRR_4 PF12799.2 AIO00920.1 - 3.7e-16 58.3 8.2 9.6e-05 21.9 0.1 5.3 3 1 2 5 5 5 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 AIO00920.1 - 7.8e-11 41.5 9.6 3.2e-05 23.5 1.0 5.1 3 2 1 4 4 4 3 Leucine rich repeat LRR_1 PF00560.28 AIO00920.1 - 1.6e-08 33.4 7.6 0.18 11.9 0.1 6.1 6 0 0 6 6 6 3 Leucine Rich Repeat LRR_7 PF13504.1 AIO00920.1 - 0.0021 17.9 9.4 1.4 9.4 0.0 5.6 6 0 0 6 6 6 2 Leucine rich repeat LRR_6 PF13516.1 AIO00920.1 - 0.0035 17.2 5.1 2.3 8.5 0.2 4.8 5 1 0 5 5 5 1 Leucine Rich repeat TPR_19 PF14559.1 AIO00921.1 - 2.4e-09 37.3 13.8 0.013 15.7 0.3 8.0 8 2 2 10 10 9 2 Tetratricopeptide repeat Clathrin PF00637.15 AIO00921.1 - 1.1e-06 28.3 0.0 1.3 8.6 0.0 5.1 4 2 0 4 4 4 2 Region in Clathrin and VPS Coatomer_WDAD PF04053.9 AIO00921.1 - 4.1e-06 25.8 0.5 0.015 14.1 0.0 3.5 2 1 1 3 3 3 2 Coatomer WD associated region TPR_14 PF13428.1 AIO00921.1 - 1.1e-05 25.5 26.3 2.4 9.0 1.6 10.7 9 2 1 10 10 10 1 Tetratricopeptide repeat TPR_7 PF13176.1 AIO00921.1 - 0.00012 21.6 22.3 0.27 11.1 0.3 7.3 10 0 0 10 10 8 3 Tetratricopeptide repeat WD40 PF00400.27 AIO00921.1 - 0.00034 20.3 1.3 0.92 9.4 0.0 3.7 4 0 0 4 4 3 2 WD domain, G-beta repeat Nucleoporin_N PF08801.6 AIO00921.1 - 0.0052 15.5 0.0 0.011 14.5 0.0 1.5 1 0 0 1 1 1 1 Nup133 N terminal like TPR_16 PF13432.1 AIO00921.1 - 0.016 15.9 28.8 0.36 11.5 1.7 7.5 7 2 0 7 7 7 0 Tetratricopeptide repeat TPR_12 PF13424.1 AIO00921.1 - 0.016 15.0 24.5 2.1 8.3 0.2 8.5 8 2 0 9 9 9 0 Tetratricopeptide repeat TPR_1 PF00515.23 AIO00921.1 - 0.058 13.0 16.9 6.6 6.5 0.1 7.0 6 1 0 6 6 6 0 Tetratricopeptide repeat TPR_2 PF07719.12 AIO00921.1 - 0.077 12.9 26.6 4.1 7.5 1.1 8.8 8 1 0 8 8 8 0 Tetratricopeptide repeat PPR PF01535.15 AIO00921.1 - 0.09 12.7 0.9 1.3e+02 2.8 0.1 5.3 4 1 0 4 4 4 0 PPR repeat TPR_11 PF13414.1 AIO00921.1 - 1.7 8.3 18.7 21 4.8 0.1 7.0 6 3 0 7 7 7 0 TPR repeat TPR_6 PF13174.1 AIO00921.1 - 6.7 7.4 28.5 0.76 10.3 1.3 7.7 7 0 0 7 7 7 0 Tetratricopeptide repeat U3snoRNP10 PF12397.3 AIO00924.1 - 0.09 12.7 0.2 0.09 12.7 0.1 2.0 3 0 0 3 3 3 0 U3 small nucleolar RNA-associated protein 10 RHD3 PF05879.7 AIO00927.1 - 6.3e-109 364.9 0.0 3.4e-95 319.5 0.0 3.2 3 0 0 3 3 3 3 Root hair defective 3 GTP-binding protein (RHD3) Dynamin_N PF00350.18 AIO00927.1 - 2.9e-05 23.9 0.1 5.1e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 Dynamin family AAA_28 PF13521.1 AIO00927.1 - 0.0011 18.9 0.3 0.0041 17.0 0.0 2.1 2 0 0 2 2 2 1 AAA domain Miro PF08477.8 AIO00927.1 - 0.03 14.8 0.0 0.071 13.6 0.0 1.6 1 0 0 1 1 1 0 Miro-like protein MMR_HSR1 PF01926.18 AIO00927.1 - 0.05 13.5 0.0 0.1 12.5 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase JAB PF01398.16 AIO00929.1 - 5.1e-22 77.7 0.0 5.5e-21 74.4 0.0 2.2 2 0 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.1 AIO00929.1 - 1.1e-21 77.0 0.1 2.2e-21 76.0 0.1 1.5 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function DUF2365 PF10157.4 AIO00929.1 - 0.0047 16.8 0.6 0.0083 16.0 0.4 1.4 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2365) DEAD PF00270.24 AIO00930.1 - 1.3e-42 145.1 0.0 2.8e-42 144.0 0.0 1.5 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 AIO00930.1 - 7.5e-27 93.0 0.1 4.4e-26 90.5 0.1 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain GRIM-19 PF06212.7 AIO00930.1 - 0.092 12.4 0.0 0.21 11.3 0.0 1.5 1 0 0 1 1 1 0 GRIM-19 protein TPR_11 PF13414.1 AIO00931.1 - 9.8e-11 41.1 14.4 4.3e-05 23.0 0.2 6.5 5 1 1 6 6 6 3 TPR repeat TPR_19 PF14559.1 AIO00931.1 - 9.9e-07 29.0 10.6 0.11 12.8 0.4 5.2 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_16 PF13432.1 AIO00931.1 - 1e-05 26.0 5.7 5.4e-05 23.7 1.8 8.2 5 1 2 7 7 7 2 Tetratricopeptide repeat TPR_2 PF07719.12 AIO00931.1 - 0.00012 21.7 26.4 0.88 9.6 0.0 8.8 9 0 0 9 9 9 3 Tetratricopeptide repeat TPR_12 PF13424.1 AIO00931.1 - 0.011 15.6 22.4 0.24 11.3 0.5 6.8 4 1 1 7 7 7 0 Tetratricopeptide repeat TPR_1 PF00515.23 AIO00931.1 - 0.19 11.3 7.6 5.2 6.8 0.8 5.0 6 0 0 6 6 6 0 Tetratricopeptide repeat HemY_N PF07219.8 AIO00931.1 - 0.22 11.0 3.3 0.89 9.1 0.0 3.2 3 0 0 3 3 3 0 HemY protein N-terminus TPR_9 PF13371.1 AIO00931.1 - 0.58 10.0 23.2 0.68 9.8 0.7 5.6 3 2 2 5 5 5 0 Tetratricopeptide repeat Kinesin PF00225.18 AIO00932.1 - 2e-31 108.9 0.0 2.7e-31 108.5 0.0 1.1 1 0 0 1 1 1 1 Kinesin motor domain MORN PF02493.15 AIO00932.1 - 3.3e-15 54.7 35.3 0.00022 20.7 0.0 7.5 7 0 0 7 7 7 5 MORN repeat Ribosomal_L22 PF00237.14 AIO00933.1 - 1.8e-30 104.9 0.2 2.2e-30 104.6 0.2 1.1 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e DUF1279 PF06916.8 AIO00934.1 - 2e-05 24.7 0.0 3.3e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1279) WW PF00397.21 AIO00934.1 - 0.00023 20.9 0.7 0.00046 19.9 0.5 1.5 1 0 0 1 1 1 1 WW domain Ribosomal_S5_C PF03719.10 AIO00935.1 - 3.1e-24 84.0 0.0 5.2e-24 83.3 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain Ribosomal_S5 PF00333.15 AIO00935.1 - 4.7e-22 77.5 0.8 7.6e-22 76.8 0.5 1.4 1 0 0 1 1 1 1 Ribosomal protein S5, N-terminal domain FoP_duplication PF13865.1 AIO00935.1 - 6.1 7.3 6.5 13 6.2 4.5 1.5 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 Aldo_ket_red PF00248.16 AIO00936.1 - 5.3e-64 215.7 0.0 6.1e-64 215.5 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family LRR_6 PF13516.1 AIO00937.1 - 4e-17 60.3 2.4 0.18 11.9 0.1 10.2 11 0 0 11 11 11 4 Leucine Rich repeat LRR_4 PF12799.2 AIO00937.1 - 3.6e-09 36.0 0.5 0.43 10.2 0.0 7.0 6 1 0 6 6 6 2 Leucine Rich repeats (2 copies) RNA_polI_A34 PF08208.6 AIO00937.1 - 0.66 9.6 7.6 18 4.9 0.0 2.3 2 0 0 2 2 2 0 DNA-directed RNA polymerase I subunit RPA34.5 CDC45 PF02724.9 AIO00937.1 - 5.9 4.7 16.8 11 3.9 11.6 1.3 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.7 AIO00937.1 - 6.3 4.5 23.2 11 3.8 16.0 1.2 1 0 0 1 1 1 0 Nop14-like family TauE PF01925.14 AIO00938.1 - 3.5e-16 59.4 29.1 1.4e-11 44.3 2.7 2.5 2 0 0 2 2 2 2 Sulfite exporter TauE/SafE DUF2207 PF09972.4 AIO00938.1 - 1.2 7.6 0.0 1.2 7.6 0.0 2.4 1 1 1 3 3 3 0 Predicted membrane protein (DUF2207) DUF4131 PF13567.1 AIO00938.1 - 2.7 7.3 0.0 2.7 7.3 0.0 3.7 4 1 0 5 5 5 0 Domain of unknown function (DUF4131) DUF2244 PF10003.4 AIO00938.1 - 5.5 6.3 18.7 4.6 6.5 1.3 3.8 3 1 0 3 3 3 0 Integral membrane protein (DUF2244) Profilin PF00235.14 AIO00940.1 - 4.5e-39 133.2 0.2 5.9e-39 132.9 0.1 1.1 1 0 0 1 1 1 1 Profilin CDC50 PF03381.10 AIO00941.1 - 2.3e-55 187.7 0.0 2.8e-55 187.4 0.0 1.1 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family DUF1708 PF08101.6 AIO00942.1 - 0.0073 15.1 0.0 0.011 14.6 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1708) Ras PF00071.17 AIO00943.1 - 1.5e-55 186.9 0.1 1.8e-55 186.7 0.1 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 AIO00943.1 - 5.5e-22 78.5 0.0 8.2e-22 77.9 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 AIO00943.1 - 3.6e-14 52.3 0.0 4.1e-14 52.1 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 AIO00943.1 - 3.7e-06 26.4 0.1 2.2e-05 23.9 0.1 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 AIO00943.1 - 9.7e-06 25.5 0.0 1.5e-05 24.9 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 AIO00943.1 - 7.5e-05 21.9 0.0 9e-05 21.7 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Septin PF00735.13 AIO00943.1 - 0.00069 18.7 0.0 0.0011 18.1 0.0 1.2 1 0 0 1 1 1 1 Septin AAA_22 PF13401.1 AIO00943.1 - 0.0029 17.7 0.0 0.01 15.9 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 AIO00943.1 - 0.003 17.5 0.0 0.0064 16.5 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain PduV-EutP PF10662.4 AIO00943.1 - 0.0045 16.4 0.2 0.022 14.2 0.0 2.0 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation NACHT PF05729.7 AIO00943.1 - 0.0058 16.2 0.0 0.01 15.5 0.0 1.2 1 0 0 1 1 1 1 NACHT domain DUF258 PF03193.11 AIO00943.1 - 0.012 14.8 0.0 0.022 13.9 0.0 1.5 1 1 0 1 1 1 0 Protein of unknown function, DUF258 RNA_helicase PF00910.17 AIO00943.1 - 0.029 14.5 0.0 0.089 12.9 0.0 2.0 1 1 0 1 1 1 0 RNA helicase YwhD PF08741.5 AIO00943.1 - 0.088 12.2 0.0 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 YwhD family cobW PF02492.14 AIO00943.1 - 0.09 12.2 0.0 11 5.4 0.0 2.1 1 1 1 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_24 PF13479.1 AIO00943.1 - 0.13 11.8 0.0 0.17 11.4 0.0 1.3 1 1 0 1 1 1 0 AAA domain Rtf2 PF04641.7 AIO00946.1 - 6.4e-26 91.1 0.4 8.1e-26 90.7 0.3 1.2 1 0 0 1 1 1 1 Rtf2 RING-finger zf-Nse PF11789.3 AIO00946.1 - 0.022 14.2 0.0 0.48 9.9 0.0 2.5 1 1 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-C3HC4_3 PF13920.1 AIO00946.1 - 0.1 12.2 1.5 0.22 11.2 1.0 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-Mss51 PF13824.1 AIO00946.1 - 0.23 11.3 1.1 0.83 9.5 0.8 2.0 1 1 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 DUF1903 PF08991.5 AIO00947.1 - 0.0013 18.8 8.1 0.0024 17.9 2.1 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF1903) CHCH PF06747.8 AIO00947.1 - 0.024 14.5 8.6 0.82 9.6 0.6 2.5 2 0 0 2 2 2 0 CHCH domain Cmc1 PF08583.5 AIO00947.1 - 0.04 13.6 11.4 0.66 9.7 0.8 3.4 2 2 1 3 3 3 0 Cytochrome c oxidase biogenesis protein Cmc1 like Pet191_N PF10203.4 AIO00947.1 - 1.6 8.8 7.0 0.44 10.6 0.3 2.3 2 0 0 2 2 2 0 Cytochrome c oxidase assembly protein PET191 UPF0203 PF05254.7 AIO00947.1 - 6.7 6.6 10.4 3.4 7.6 0.1 3.1 1 1 2 3 3 3 0 Uncharacterised protein family (UPF0203) Colipase-like PF15083.1 AIO00947.1 - 7 6.6 6.9 2.7 7.9 0.7 2.1 1 1 0 2 2 2 0 Colipase-like DUF3716 PF12511.3 AIO00947.1 - 8 6.1 10.9 1.9 8.1 0.9 3.2 1 1 2 3 3 3 0 Protein of unknown function (DUF3716) zf-C3HC4_3 PF13920.1 AIO00948.1 - 8.9e-06 25.2 17.8 1.5e-05 24.5 12.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) DEAD PF00270.24 AIO00949.1 - 1.8e-31 108.8 0.3 8.4e-31 106.7 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 AIO00949.1 - 2.1e-25 88.3 0.1 6.4e-25 86.8 0.1 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 AIO00949.1 - 6.5e-08 32.6 0.4 2.1e-07 30.9 0.0 2.0 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit SNF2_N PF00176.18 AIO00949.1 - 0.013 14.2 0.0 0.028 13.2 0.0 1.5 1 0 0 1 1 1 0 SNF2 family N-terminal domain YL1 PF05764.8 AIO00950.1 - 0.4 10.2 19.1 0.025 14.1 9.3 1.9 2 0 0 2 2 2 0 YL1 nuclear protein Nop14 PF04147.7 AIO00950.1 - 1.4 6.7 12.0 2.2 6.1 8.3 1.2 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.7 AIO00950.1 - 1.7 7.8 15.1 0.27 10.4 7.8 1.5 2 0 0 2 2 2 0 SDA1 TRAP_alpha PF03896.11 AIO00950.1 - 9 5.1 10.1 6.8 5.5 3.4 2.6 3 0 0 3 3 3 0 Translocon-associated protein (TRAP), alpha subunit DnaJ PF00226.26 AIO00951.1 - 2.2e-11 43.2 0.0 6.8e-11 41.7 0.0 1.9 1 0 0 1 1 1 1 DnaJ domain DUF2514 PF10721.4 AIO00951.1 - 4 7.1 13.3 1.5 8.4 5.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2514) Vac_Fusion PF02346.11 AIO00952.1 - 0.035 13.5 0.3 0.22 10.9 0.0 2.3 2 0 0 2 2 2 0 Chordopoxvirus fusion protein WD40 PF00400.27 AIO00953.1 - 1e-18 66.3 4.7 3.7e-06 26.6 0.1 5.6 5 0 0 5 5 5 3 WD domain, G-beta repeat MMS1_N PF10433.4 AIO00953.1 - 0.032 12.3 0.0 0.054 11.6 0.0 1.4 1 0 0 1 1 1 0 Mono-functional DNA-alkylating methyl methanesulfonate N-term AMMECR1 PF01871.12 AIO00955.1 - 7e-49 165.2 0.0 8.4e-49 164.9 0.0 1.0 1 0 0 1 1 1 1 AMMECR1 DSPc PF00782.15 AIO00956.1 - 5.6e-14 51.8 0.0 1.1e-13 50.8 0.0 1.6 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 AIO00956.1 - 2.7e-11 43.2 0.0 6.9e-11 41.9 0.0 1.5 2 0 0 2 2 2 1 Protein-tyrosine phosphatase CDKN3 PF05706.7 AIO00956.1 - 7.6e-06 25.4 0.0 1.4e-05 24.5 0.0 1.4 1 0 0 1 1 1 1 Cyclin-dependent kinase inhibitor 3 (CDKN3) PTPlike_phytase PF14566.1 AIO00956.1 - 0.00012 22.1 0.0 0.00024 21.1 0.0 1.5 1 0 0 1 1 1 1 Inositol hexakisphosphate Y_phosphatase3 PF13350.1 AIO00956.1 - 0.0016 18.6 0.0 0.0043 17.3 0.0 1.7 1 0 0 1 1 1 1 Tyrosine phosphatase family RhoGAP PF00620.22 AIO00956.1 - 0.0066 16.0 0.0 0.012 15.2 0.0 1.4 1 0 0 1 1 1 1 RhoGAP domain AKAP7_NLS PF10469.4 AIO00957.1 - 2.8e-41 141.5 0.0 3.5e-41 141.2 0.0 1.1 1 0 0 1 1 1 1 AKAP7 2'5' RNA ligase-like domain 2_5_RNA_ligase2 PF13563.1 AIO00957.1 - 1.7e-08 34.3 0.0 2.3e-08 33.8 0.0 1.2 1 0 0 1 1 1 1 2'-5' RNA ligase superfamily EF-hand_7 PF13499.1 AIO00958.1 - 1e-10 41.6 0.6 2.6e-06 27.4 0.2 2.9 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_6 PF13405.1 AIO00958.1 - 3.3e-10 38.9 0.9 0.00078 19.1 0.1 3.8 3 1 1 4 4 4 2 EF-hand domain EF-hand_1 PF00036.27 AIO00958.1 - 3.5e-09 35.3 0.3 0.002 17.3 0.1 4.0 4 0 0 4 4 4 2 EF hand EF-hand_8 PF13833.1 AIO00958.1 - 2.7e-07 30.0 7.8 0.001 18.6 0.5 4.7 2 1 3 5 5 5 3 EF-hand domain pair EFhand_Ca_insen PF08726.5 AIO00958.1 - 0.00061 19.7 0.5 0.023 14.6 0.1 2.5 2 1 0 2 2 2 1 Ca2+ insensitive EF hand EF-hand_5 PF13202.1 AIO00958.1 - 0.0079 15.5 3.9 0.12 11.8 0.1 3.2 3 0 0 3 3 3 1 EF hand DUF2465 PF10239.4 AIO00958.1 - 0.061 12.5 0.0 0.099 11.8 0.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2465) DUF2059 PF09832.4 AIO00958.1 - 0.11 12.5 0.5 0.66 10.0 0.0 2.4 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2059) Trypsin_2 PF13365.1 AIO00959.1 - 0.0016 18.4 0.0 0.011 15.7 0.0 2.5 1 1 0 1 1 1 1 Trypsin-like peptidase domain Kinesin PF00225.18 AIO00960.1 - 4.3e-99 331.3 0.1 4.3e-99 331.3 0.0 2.9 4 0 0 4 4 4 1 Kinesin motor domain AAA_22 PF13401.1 AIO00960.1 - 0.23 11.6 0.0 0.23 11.6 0.0 3.7 4 1 0 4 4 4 0 AAA domain S4 PF01479.20 AIO00961.1 - 0.0011 18.3 0.0 0.0021 17.4 0.0 1.5 1 0 0 1 1 1 1 S4 domain UQ_con PF00179.21 AIO00962.1 - 2.6e-34 117.6 0.0 4.2e-34 116.9 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Mut7-C PF01927.11 AIO00963.1 - 1.4e-48 164.6 0.6 2.2e-48 163.9 0.4 1.3 1 0 0 1 1 1 1 Mut7-C RNAse domain DUF758 PF05527.6 AIO00963.1 - 0.056 13.0 0.0 0.093 12.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF758) zf-TFIIIC PF12660.2 AIO00963.1 - 0.15 11.9 1.4 1.4 8.8 0.1 2.4 2 0 0 2 2 2 0 Putative zinc-finger of transcription factor IIIC complex LSM PF01423.17 AIO00964.1 - 2.6e-10 39.6 0.1 3.4e-10 39.3 0.1 1.2 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 AIO00964.1 - 0.065 13.1 0.0 0.08 12.8 0.0 1.3 1 0 0 1 1 1 0 Ataxin 2 SM domain LRR_4 PF12799.2 AIO00966.1 - 7.5e-15 54.1 7.4 1e-06 28.2 0.0 4.7 3 2 1 4 4 4 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 AIO00966.1 - 1.6e-12 46.9 7.4 7.9e-08 31.9 1.3 4.5 2 1 2 4 4 4 4 Leucine rich repeat LRR_1 PF00560.28 AIO00966.1 - 6.4e-06 25.5 8.7 3 8.2 0.0 6.9 7 0 0 7 7 7 2 Leucine Rich Repeat LRR_6 PF13516.1 AIO00966.1 - 0.00014 21.5 4.6 0.71 10.1 0.1 4.9 4 1 1 5 5 5 1 Leucine Rich repeat LRR_7 PF13504.1 AIO00966.1 - 0.0027 17.6 12.0 0.89 10.0 0.2 6.0 6 0 0 6 6 6 2 Leucine rich repeat RRM_6 PF14259.1 AIO00968.1 - 3.8e-12 46.0 0.2 3.1e-05 23.8 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 AIO00968.1 - 1.1e-07 31.5 0.7 0.013 15.3 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 AIO00968.1 - 1.4e-07 30.9 1.2 0.00072 19.1 0.1 2.4 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Cyclin_N PF00134.18 AIO00969.1 - 3.6e-08 33.0 2.1 7.9e-08 31.9 0.5 2.0 2 0 0 2 2 2 1 Cyclin, N-terminal domain RIC1 PF07064.8 AIO00970.1 - 7.3e-68 228.8 0.0 1.6e-67 227.7 0.0 1.6 1 0 0 1 1 1 1 RIC1 Pkinase PF00069.20 AIO00971.1 - 1.5e-45 155.4 0.0 2.5e-45 154.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AIO00971.1 - 2.9e-28 98.6 0.0 5.1e-28 97.8 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 AIO00971.1 - 0.0014 18.4 0.0 0.0032 17.2 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family DUF3772 PF12607.3 AIO00971.1 - 0.0064 16.0 0.0 0.015 14.9 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3772) Kinase-like PF14531.1 AIO00971.1 - 0.039 12.9 0.0 0.093 11.6 0.0 1.6 1 0 0 1 1 1 0 Kinase-like Seadorna_VP7 PF07387.6 AIO00971.1 - 0.072 11.9 0.0 0.13 11.0 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 Pkinase PF00069.20 AIO00974.1 - 6e-48 163.2 0.0 9.7e-48 162.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AIO00974.1 - 1.5e-35 122.5 0.0 3e-35 121.5 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase DUF1418 PF07214.7 AIO00974.1 - 0.088 12.4 0.7 0.27 10.8 0.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1418) Cyclin PF08613.6 AIO00975.1 - 6.1e-25 88.3 0.7 7.7e-25 88.0 0.5 1.1 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.18 AIO00975.1 - 1.5e-10 40.6 0.4 1.9e-10 40.3 0.2 1.1 1 0 0 1 1 1 1 Cyclin, N-terminal domain RRM_5 PF13893.1 AIO00977.1 - 3.3e-06 26.8 0.0 0.041 13.7 0.0 2.7 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 AIO00977.1 - 0.016 14.8 0.0 0.11 12.1 0.0 2.1 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 AIO00978.1 - 3.3e-13 49.2 0.0 0.00036 20.3 0.0 4.3 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 AIO00978.1 - 9e-13 48.0 0.0 0.017 15.0 0.0 4.3 4 0 0 4 4 4 4 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 AIO00978.1 - 6.2e-11 41.7 0.0 0.0026 17.3 0.0 4.3 4 1 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 AIO00978.1 - 0.063 13.1 0.0 6 6.7 0.0 2.8 3 0 0 3 3 3 0 RNA binding motif tRNA-synt_2d PF01409.15 AIO00980.1 - 1.4e-79 266.8 0.1 2e-79 266.3 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II core domain (F) tRNA-synt_2 PF00152.15 AIO00980.1 - 3.7e-05 22.6 4.5 7e-05 21.7 0.2 2.5 2 1 1 3 3 3 1 tRNA synthetases class II (D, K and N) tRNA-synt_2b PF00587.20 AIO00980.1 - 0.00018 21.1 0.1 0.00047 19.7 0.1 1.7 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) DUF507 PF04368.8 AIO00980.1 - 0.045 13.3 0.1 0.12 12.0 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF507) Ribosomal_L18ae PF01775.12 AIO00981.1 - 3.7e-40 136.6 1.3 5.6e-40 136.0 0.9 1.3 1 0 0 1 1 1 1 Ribosomal L18ae/LX protein domain CTP_transf_2 PF01467.21 AIO00982.1 - 3.2e-33 114.9 0.1 2.2e-17 63.5 0.0 2.5 2 1 0 2 2 2 2 Cytidylyltransferase FAD_syn PF06574.7 AIO00982.1 - 3.1e-05 23.6 1.7 0.086 12.4 0.1 3.3 2 2 0 2 2 2 2 FAD synthetase CoA_binding_3 PF13727.1 AIO00982.1 - 0.05 13.4 0.0 0.084 12.7 0.0 1.3 1 0 0 1 1 1 0 CoA-binding domain CENP-F_leu_zip PF10473.4 AIO00983.1 - 0.002 17.9 0.6 0.0033 17.2 0.4 1.4 1 1 0 1 1 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Abhydrolase_6 PF12697.2 AIO00984.1 - 1.7e-18 67.3 0.0 2.2e-18 67.0 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 AIO00984.1 - 2.1e-06 27.5 0.0 2.9e-06 27.0 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 AIO00984.1 - 6.4e-06 25.8 0.0 3.9e-05 23.3 0.0 1.9 2 0 0 2 2 2 1 alpha/beta hydrolase fold Lipase_3 PF01764.20 AIO00984.1 - 0.0009 18.8 0.0 0.0017 17.9 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) Ser_hydrolase PF06821.8 AIO00984.1 - 0.0073 15.9 0.0 0.018 14.6 0.0 1.6 2 0 0 2 2 2 1 Serine hydrolase PGAP1 PF07819.8 AIO00984.1 - 0.1 12.1 0.1 0.15 11.6 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein V_ATPase_I PF01496.14 AIO00985.1 - 2e-195 650.9 1.5 3.2e-195 650.2 1.0 1.2 1 1 0 1 1 1 1 V-type ATPase 116kDa subunit family DAO PF01266.19 AIO00986.1 - 1e-07 31.1 0.2 3.1e-06 26.3 0.0 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase GMC_oxred_N PF00732.14 AIO00986.1 - 2.2e-06 27.0 0.1 0.0024 17.0 0.0 3.0 2 1 0 2 2 2 2 GMC oxidoreductase FAD_binding_2 PF00890.19 AIO00986.1 - 3.7e-05 22.7 0.6 0.00046 19.1 0.1 2.2 2 0 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.1 AIO00986.1 - 0.00085 19.3 0.1 0.0025 17.8 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 AIO00986.1 - 0.0015 18.6 0.0 0.0036 17.3 0.0 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 AIO00986.1 - 0.0027 16.4 0.1 0.0042 15.7 0.1 1.2 1 0 0 1 1 1 1 Tryptophan halogenase Pyr_redox_2 PF07992.9 AIO00986.1 - 0.0033 17.3 0.0 0.0063 16.4 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 AIO00986.1 - 0.0061 15.5 0.3 0.01 14.8 0.2 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_9 PF13454.1 AIO00986.1 - 0.0094 15.7 0.1 0.022 14.5 0.1 1.6 1 0 0 1 1 1 1 FAD-NAD(P)-binding HI0933_like PF03486.9 AIO00986.1 - 0.031 12.7 0.1 0.044 12.2 0.1 1.1 1 0 0 1 1 1 0 HI0933-like protein AlaDh_PNT_C PF01262.16 AIO00986.1 - 0.062 12.8 0.1 0.13 11.8 0.1 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain GIDA PF01134.17 AIO00986.1 - 0.086 11.6 0.1 0.14 11.0 0.0 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A CLASP_N PF12348.3 AIO00987.1 - 1e-13 51.2 1.6 1e-13 51.2 1.1 3.2 4 0 0 4 4 4 1 CLASP N terminal HEAT PF02985.17 AIO00987.1 - 0.1 12.7 24.0 1.3 9.3 0.0 8.4 9 0 0 9 9 9 0 HEAT repeat Ipi1_N PF12333.3 AIO00987.1 - 0.16 11.9 9.2 24 4.9 0.1 5.3 5 1 0 5 5 5 0 Rix1 complex component involved in 60S ribosome maturation SNase PF00565.12 AIO00988.1 - 3.8e-52 175.1 1.9 3.1e-16 59.5 0.0 5.3 5 0 0 5 5 5 5 Staphylococcal nuclease homologue TUDOR PF00567.19 AIO00988.1 - 3.7e-17 62.2 0.0 6.9e-17 61.4 0.0 1.4 1 0 0 1 1 1 1 Tudor domain DUF4537 PF15057.1 AIO00988.1 - 0.007 16.1 0.0 0.018 14.7 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4537) UQ_con PF00179.21 AIO00989.1 - 1.2e-40 138.1 0.0 1.6e-40 137.7 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Peptidase_C2 PF00648.16 AIO00990.1 - 9.3e-05 21.5 0.0 0.00021 20.3 0.0 1.5 1 0 0 1 1 1 1 Calpain family cysteine protease RRM_1 PF00076.17 AIO00991.1 - 0.045 13.3 0.0 0.096 12.3 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 AIO00991.1 - 0.15 12.0 0.0 0.35 10.8 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Vps23_core PF09454.5 AIO00992.1 - 3.1e-19 68.3 0.1 8.8e-19 66.8 0.1 1.8 1 0 0 1 1 1 1 Vps23 core domain CUE PF02845.11 AIO00992.1 - 0.25 10.8 1.1 0.64 9.5 0.1 2.2 1 1 1 2 2 2 0 CUE domain Cpn60_TCP1 PF00118.19 AIO00993.1 - 3.3e-145 484.4 0.4 3.8e-145 484.2 0.3 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Y_phosphatase2 PF03162.8 AIO00994.1 - 4e-22 78.3 0.0 7e-21 74.2 0.0 2.3 1 1 0 1 1 1 1 Tyrosine phosphatase family Pkinase PF00069.20 AIO00995.1 - 2.3e-30 105.6 0.1 2.3e-25 89.2 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 AIO00995.1 - 3.6e-17 62.2 0.3 7e-17 61.3 0.2 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase CIMR PF00878.13 AIO00995.1 - 0.027 14.2 0.0 0.058 13.1 0.0 1.5 1 0 0 1 1 1 0 Cation-independent mannose-6-phosphate receptor repeat Maf PF02545.9 AIO00996.1 - 6.8e-19 67.7 0.0 8.1e-19 67.4 0.0 1.1 1 0 0 1 1 1 1 Maf-like protein ATP11 PF06644.6 AIO00996.1 - 0.15 11.5 0.1 0.23 10.9 0.1 1.2 1 0 0 1 1 1 0 ATP11 protein Lge1 PF11488.3 AIO00997.1 - 0.0039 17.3 0.5 0.0039 17.3 0.3 3.6 4 0 0 4 4 4 1 Transcriptional regulatory protein LGE1 TMF_DNA_bd PF12329.3 AIO00997.1 - 0.076 12.8 18.9 0.57 10.0 0.7 5.0 5 0 0 5 5 5 0 TATA element modulatory factor 1 DNA binding TBPIP PF07106.8 AIO00997.1 - 1.3 8.5 22.5 0.77 9.2 1.0 4.3 3 2 1 4 4 4 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Metallophos_2 PF12850.2 AIO00998.1 - 8.1e-12 45.2 0.0 9.9e-12 44.9 0.0 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain WD40 PF00400.27 AIO00999.1 - 1.2e-14 53.4 8.2 0.00011 21.9 0.1 5.5 6 0 0 6 6 6 4 WD domain, G-beta repeat LSM PF01423.17 AIO01000.1 - 3.6e-14 52.0 0.1 4.1e-14 51.8 0.1 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 AIO01000.1 - 0.12 12.3 0.1 0.14 12.0 0.0 1.2 1 0 0 1 1 1 0 Ataxin 2 SM domain HECT PF00632.20 AIO01002.1 - 1.5e-73 247.7 0.0 2.2e-73 247.2 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) HEAT_2 PF13646.1 AIO01002.1 - 0.00011 22.4 1.3 0.088 13.1 0.0 3.8 2 1 1 3 3 3 2 HEAT repeats ZZ PF00569.12 AIO01002.1 - 0.00072 19.0 8.7 0.00072 19.0 6.0 2.2 2 0 0 2 2 2 1 Zinc finger, ZZ type MUG2_C PF08593.5 AIO01002.1 - 0.18 12.0 0.0 0.63 10.3 0.0 2.0 1 0 0 1 1 1 0 Meiotically up-regulated glycoproteins C-terminal CRM1_C PF08767.6 AIO01003.1 - 1e-61 208.6 0.6 1e-61 208.6 0.4 3.0 4 0 0 4 4 4 1 CRM1 C terminal Xpo1 PF08389.7 AIO01003.1 - 3.7e-26 91.8 1.3 3.7e-26 91.8 0.9 3.4 4 1 0 4 4 4 1 Exportin 1-like protein IBN_N PF03810.14 AIO01003.1 - 1.6e-07 31.1 0.3 1.2e-06 28.3 0.2 2.7 2 0 0 2 2 2 1 Importin-beta N-terminal domain Mito_carr PF00153.22 AIO01004.1 - 9.3e-49 163.1 0.9 3.1e-16 58.8 0.0 3.1 2 1 1 3 3 3 3 Mitochondrial carrier protein DUF3815 PF12821.2 AIO01004.1 - 0.0021 17.9 1.1 0.0084 16.0 0.4 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF3815) PgaD PF13994.1 AIO01004.1 - 0.047 13.1 0.8 4.1 6.8 0.2 2.2 2 0 0 2 2 2 0 PgaD-like protein Mito_carr PF00153.22 AIO01005.1 - 1.6e-49 165.5 1.4 1.5e-16 59.8 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein PPR_2 PF13041.1 AIO01007.1 - 0.0079 16.1 0.0 20 5.2 0.0 3.6 3 0 0 3 3 3 2 PPR repeat family PPR_3 PF13812.1 AIO01007.1 - 0.018 15.2 5.7 0.9 9.9 0.1 4.6 4 0 0 4 4 4 0 Pentatricopeptide repeat domain ELO PF01151.13 AIO01009.1 - 7.8e-53 179.3 16.8 1.1e-52 178.8 11.6 1.2 1 0 0 1 1 1 1 GNS1/SUR4 family DUF3278 PF11683.3 AIO01009.1 - 0.56 10.2 2.8 1.1 9.2 0.0 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF3278) Ank_2 PF12796.2 AIO01011.1 - 1.7e-10 41.0 0.0 6e-10 39.3 0.0 1.9 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 AIO01011.1 - 2.4e-10 40.6 0.2 7.7e-10 39.0 0.1 1.9 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank PF00023.25 AIO01011.1 - 1.2e-09 37.4 1.5 0.0002 20.9 0.2 2.8 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.1 AIO01011.1 - 1.7e-07 31.2 2.0 5.1e-07 29.7 1.4 1.8 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 AIO01011.1 - 6.6e-06 25.8 1.9 0.0037 17.3 0.1 3.5 3 0 0 3 3 3 2 Ankyrin repeat PCI_Csn8 PF10075.4 AIO01013.1 - 1.6e-27 95.9 0.0 2.5e-27 95.4 0.0 1.2 1 0 0 1 1 1 1 COP9 signalosome, subunit CSN8 SAC3_GANP PF03399.11 AIO01013.1 - 7.3e-21 74.6 0.4 1.1e-20 74.1 0.2 1.2 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family HhH-GPD PF00730.20 AIO01013.1 - 0.033 14.4 0.0 0.074 13.3 0.0 1.5 1 0 0 1 1 1 0 HhH-GPD superfamily base excision DNA repair protein PPR_2 PF13041.1 AIO01014.1 - 1.5e-42 143.3 15.0 1.5e-11 44.0 0.0 11.5 9 2 3 12 12 12 8 PPR repeat family PPR_3 PF13812.1 AIO01014.1 - 6.3e-19 66.6 27.6 1.1e-06 28.4 0.0 13.0 14 2 0 14 14 14 4 Pentatricopeptide repeat domain PPR PF01535.15 AIO01014.1 - 8.2e-16 56.8 10.5 2.1e-05 24.1 0.0 9.4 8 0 0 8 8 8 4 PPR repeat PPR_1 PF12854.2 AIO01014.1 - 1.7e-07 30.5 19.9 0.0008 18.8 0.0 8.7 9 0 0 9 9 9 1 PPR repeat COX5A PF02284.11 AIO01014.1 - 1.4e-05 25.0 0.7 0.016 15.1 0.0 3.2 2 1 1 3 3 3 2 Cytochrome c oxidase subunit Va ECSIT PF06239.6 AIO01014.1 - 5.3e-05 22.1 0.8 1.5 7.6 0.1 5.3 3 2 1 4 4 4 1 Evolutionarily conserved signalling intermediate in Toll pathway RPM2 PF08579.6 AIO01014.1 - 0.0035 17.4 3.2 5.9 7.0 0.1 4.8 2 2 1 3 3 3 2 Mitochondrial ribonuclease P subunit (RPM2) PPP1R35_C PF15503.1 AIO01014.1 - 0.055 12.9 0.2 0.24 10.9 0.1 2.0 1 1 0 1 1 1 0 Protein phosphatase 1 regulatory subunit 35 C-terminus TPR_15 PF13429.1 AIO01014.1 - 0.065 12.2 1.1 0.11 11.5 0.3 1.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TSC22 PF01166.13 AIO01015.1 - 0.11 12.4 0.2 0.11 12.4 0.1 3.0 3 0 0 3 3 3 0 TSC-22/dip/bun family ArfGap PF01412.13 AIO01016.1 - 2.1e-27 95.2 0.0 3.7e-27 94.4 0.0 1.3 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf TF_Zn_Ribbon PF08271.7 AIO01016.1 - 0.067 12.5 2.1 0.11 11.8 1.5 1.4 1 0 0 1 1 1 0 TFIIB zinc-binding Apolipoprotein PF01442.13 AIO01016.1 - 0.12 11.9 0.0 0.17 11.3 0.0 1.2 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain DUF2413 PF10310.4 AIO01016.1 - 0.12 11.1 1.2 0.16 10.7 0.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) PHTB1_N PF14727.1 AIO01017.1 - 9.1e-93 311.4 0.0 1.7e-67 228.2 0.0 2.1 2 0 0 2 2 2 2 PTHB1 N-terminus PHTB1_C PF14728.1 AIO01017.1 - 7.6e-46 156.5 0.2 1.1e-45 156.0 0.1 1.1 1 0 0 1 1 1 1 PTHB1 C-terminus BBS2_Mid PF14783.1 AIO01017.1 - 0.13 12.0 0.0 0.28 10.9 0.0 1.5 1 0 0 1 1 1 0 Ciliary BBSome complex subunit 2, middle region UCH PF00443.24 AIO01018.1 - 2.1e-33 115.6 0.0 2.9e-33 115.1 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 AIO01018.1 - 6.4e-20 71.7 0.1 7.7e-16 58.3 0.0 2.0 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase CRAL_TRIO PF00650.15 AIO01019.1 - 6.8e-36 123.1 0.0 9.8e-36 122.6 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain GOLD_2 PF13897.1 AIO01019.1 - 0.00023 21.4 0.1 0.16 12.1 0.0 2.3 1 1 1 2 2 2 2 Golgi-dynamics membrane-trafficking CRAL_TRIO_N PF03765.10 AIO01019.1 - 0.094 12.8 0.0 0.2 11.7 0.0 1.6 1 0 0 1 1 1 0 CRAL/TRIO, N-terminal domain UBA_4 PF14555.1 AIO01019.1 - 0.49 9.9 2.0 6.5 6.3 0.5 2.4 2 0 0 2 2 2 0 UBA-like domain CRAL_TRIO PF00650.15 AIO01020.1 - 4.3e-33 114.0 0.0 6.1e-33 113.5 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 AIO01020.1 - 0.00094 19.2 0.2 0.0021 18.1 0.2 1.6 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.1 AIO01020.1 - 0.0025 17.7 0.0 0.0056 16.5 0.0 1.5 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain CRAL_TRIO PF00650.15 AIO01021.1 - 1.5e-28 99.3 0.0 3.5e-28 98.1 0.0 1.6 1 1 0 1 1 1 1 CRAL/TRIO domain SHS2_Rpb7-N PF03876.12 AIO01022.1 - 3.8e-15 55.7 0.0 6.1e-15 55.0 0.0 1.4 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 Pkinase PF00069.20 AIO01023.1 - 3.7e-10 39.3 0.0 6.8e-10 38.5 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AIO01023.1 - 2.5e-06 26.7 0.0 3.7e-06 26.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 AIO01023.1 - 4.5e-05 23.2 0.9 0.00014 21.6 0.0 2.1 2 0 0 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 AIO01023.1 - 0.0021 17.6 0.0 0.0038 16.8 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase Pep_deformylase PF01327.16 AIO01024.1 - 4.6e-25 87.8 0.0 6.7e-25 87.3 0.0 1.2 1 0 0 1 1 1 1 Polypeptide deformylase WLM PF08325.5 AIO01025.1 - 2.8e-30 105.5 0.0 1.2e-29 103.5 0.0 1.9 1 1 0 1 1 1 1 WLM domain DUF45 PF01863.12 AIO01025.1 - 0.0058 16.4 2.3 0.0092 15.7 1.6 1.2 1 0 0 1 1 1 1 Protein of unknown function DUF45 DUF3642 PF12182.3 AIO01025.1 - 0.12 12.7 0.0 0.22 11.9 0.0 1.3 1 0 0 1 1 1 0 Bacterial lipoprotein OrfB_Zn_ribbon PF07282.6 AIO01025.1 - 0.37 10.4 2.1 0.98 9.1 1.4 1.7 1 0 0 1 1 1 0 Putative transposase DNA-binding domain RecR PF02132.10 AIO01025.1 - 1.5 8.3 6.7 0.57 9.6 2.6 1.8 2 0 0 2 2 2 0 RecR protein Peptidase_C97 PF05903.9 AIO01027.1 - 7.8e-17 61.4 0.0 1.4e-16 60.6 0.0 1.4 1 0 0 1 1 1 1 PPPDE putative peptidase domain CPSF_A PF03178.10 AIO01028.1 - 1.4e-59 201.7 0.0 2.3e-59 201.1 0.0 1.3 1 0 0 1 1 1 1 CPSF A subunit region MMS1_N PF10433.4 AIO01028.1 - 1.5e-07 30.0 0.0 1.6e-06 26.5 0.0 2.3 2 1 0 2 2 2 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term LicD PF04991.8 AIO01029.1 - 5.5e-10 39.7 0.0 1e-09 38.8 0.0 1.4 1 0 0 1 1 1 1 LicD family AAA_17 PF13207.1 AIO01030.1 - 3.4e-08 34.3 0.0 8.1e-08 33.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain ADK PF00406.17 AIO01030.1 - 7.8e-08 32.3 0.0 7.5e-07 29.1 0.0 2.2 1 1 1 2 2 2 1 Adenylate kinase mRNA_cap_enzyme PF01331.14 AIO01030.1 - 8.5e-07 28.8 0.0 1.4e-06 28.1 0.0 1.3 1 0 0 1 1 1 1 mRNA capping enzyme, catalytic domain AAA_33 PF13671.1 AIO01030.1 - 5.4e-05 23.0 0.0 0.00013 21.8 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 AIO01030.1 - 0.0001 22.6 0.0 0.00022 21.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain mRNA_cap_C PF03919.10 AIO01030.1 - 0.00033 20.9 0.0 0.001 19.3 0.0 2.0 1 0 0 1 1 1 1 mRNA capping enzyme, C-terminal domain Thymidylate_kin PF02223.12 AIO01030.1 - 0.00099 18.5 0.0 0.6 9.4 0.0 2.4 2 0 0 2 2 2 2 Thymidylate kinase AAA_22 PF13401.1 AIO01030.1 - 0.006 16.7 0.0 0.018 15.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain DNA_ligase_A_M PF01068.16 AIO01030.1 - 0.01 15.1 0.0 4.1 6.7 0.0 2.4 2 0 0 2 2 2 0 ATP dependent DNA ligase domain Zeta_toxin PF06414.7 AIO01030.1 - 0.031 13.3 0.1 0.11 11.5 0.0 1.8 2 0 0 2 2 2 0 Zeta toxin AAA_14 PF13173.1 AIO01030.1 - 0.036 13.9 0.0 0.067 13.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain MobB PF03205.9 AIO01030.1 - 0.043 13.5 0.1 0.84 9.3 0.0 2.9 3 0 0 3 3 3 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_28 PF13521.1 AIO01030.1 - 0.052 13.5 0.0 0.13 12.2 0.0 1.6 2 0 0 2 2 2 0 AAA domain SRP54 PF00448.17 AIO01030.1 - 0.084 12.3 0.0 0.13 11.6 0.0 1.2 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_17 PF13207.1 AIO01031.1 - 4.7e-06 27.4 0.0 1.2e-05 26.1 0.0 1.8 1 1 0 1 1 1 1 AAA domain MobB PF03205.9 AIO01031.1 - 0.0016 18.1 0.0 0.0033 17.1 0.0 1.5 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_33 PF13671.1 AIO01031.1 - 0.036 13.9 0.0 0.074 12.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 AIO01031.1 - 0.065 13.2 0.1 0.15 12.0 0.0 1.6 1 1 0 1 1 1 0 AAA ATPase domain Ku_N PF03731.10 AIO01031.1 - 0.085 12.2 0.0 0.14 11.5 0.0 1.2 1 0 0 1 1 1 0 Ku70/Ku80 N-terminal alpha/beta domain AAA PF00004.24 AIO01031.1 - 0.088 13.0 0.1 0.26 11.5 0.0 1.8 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) PAM2 PF07145.10 AIO01031.1 - 0.13 11.8 4.0 0.45 10.1 1.2 2.5 2 0 0 2 2 2 0 Ataxin-2 C-terminal region Uds1 PF15456.1 AIO01032.1 - 0.36 10.8 2.9 2.3 8.2 2.0 1.9 1 1 0 1 1 1 0 Up-regulated During Septation Sec63 PF02889.11 AIO01034.1 - 4.5e-38 131.2 0.3 4.5e-35 121.3 0.0 2.7 3 0 0 3 3 3 2 Sec63 Brl domain DEAD PF00270.24 AIO01034.1 - 2.8e-21 75.7 0.1 1.9e-20 72.9 0.1 2.3 1 1 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 AIO01034.1 - 1.1e-06 28.3 0.0 2.5e-06 27.2 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 AIO01034.1 - 1.6e-05 24.8 0.0 4e-05 23.5 0.0 1.6 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit T2SE PF00437.15 AIO01034.1 - 0.012 14.5 0.4 0.052 12.4 0.0 2.2 3 0 0 3 3 3 0 Type II/IV secretion system protein AAA_22 PF13401.1 AIO01034.1 - 0.12 12.4 0.0 20 5.3 0.0 2.6 2 0 0 2 2 2 0 AAA domain Cyclase PF04199.8 AIO01035.1 - 5.4e-40 136.8 0.0 1e-39 135.9 0.0 1.4 1 0 0 1 1 1 1 Putative cyclase Gemini_AL2 PF01440.11 AIO01038.1 - 0.084 12.9 0.1 0.13 12.3 0.1 1.2 1 0 0 1 1 1 0 Geminivirus AL2 protein PI3_PI4_kinase PF00454.22 AIO01040.1 - 4.2e-38 131.1 0.2 8.6e-38 130.1 0.1 1.6 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FATC PF02260.15 AIO01040.1 - 4.8e-12 45.0 1.5 4.8e-12 45.0 1.0 2.6 3 0 0 3 3 3 1 FATC domain FAT PF02259.18 AIO01040.1 - 2.3e-11 43.3 1.3 2.2e-05 23.5 0.1 3.1 2 1 0 2 2 2 2 FAT domain MIP-T3 PF10243.4 AIO01041.1 - 1.2e-17 63.5 1.4 1.8e-17 63.0 0.0 1.7 2 0 0 2 2 2 1 Microtubule-binding protein MIP-T3 rRNA_processing PF08524.6 AIO01043.1 - 3.9e-07 29.9 22.2 3.9e-07 29.9 15.4 2.2 1 1 1 2 2 2 1 rRNA processing VGLL4 PF15245.1 AIO01043.1 - 0.45 10.3 10.6 0.71 9.6 7.3 1.4 1 1 0 1 1 1 0 Transcription cofactor vestigial-like protein 4 Peptidase_M41 PF01434.13 AIO01045.1 - 2.1e-49 167.8 0.5 2.1e-49 167.8 0.3 1.5 2 0 0 2 2 2 1 Peptidase family M41 AAA PF00004.24 AIO01045.1 - 6.8e-41 139.5 0.0 1.3e-40 138.6 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 AIO01045.1 - 0.00026 21.0 0.2 0.0027 17.7 0.1 2.4 1 1 1 2 2 2 1 AAA ATPase domain AAA_19 PF13245.1 AIO01045.1 - 0.0011 18.6 0.4 0.0046 16.6 0.3 2.1 1 0 0 1 1 1 1 Part of AAA domain RuvB_N PF05496.7 AIO01045.1 - 0.0015 17.6 0.0 0.003 16.6 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 AIO01045.1 - 0.0016 18.5 0.1 0.013 15.6 0.1 2.3 1 1 0 1 1 1 1 AAA domain AAA_25 PF13481.1 AIO01045.1 - 0.0034 16.7 1.1 0.04 13.3 0.2 2.4 1 1 1 2 2 2 1 AAA domain TIP49 PF06068.8 AIO01045.1 - 0.0077 14.9 0.1 0.016 13.9 0.0 1.5 1 1 0 1 1 1 1 TIP49 C-terminus AAA_17 PF13207.1 AIO01045.1 - 0.012 16.4 0.0 0.031 15.0 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.9 AIO01045.1 - 0.012 15.3 0.2 0.067 12.9 0.1 2.3 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) Zeta_toxin PF06414.7 AIO01045.1 - 0.014 14.4 0.0 0.03 13.4 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin IstB_IS21 PF01695.12 AIO01045.1 - 0.022 14.1 0.1 0.049 13.0 0.1 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein Sigma54_activat PF00158.21 AIO01045.1 - 0.03 13.7 0.0 0.18 11.2 0.0 2.2 1 1 0 1 1 1 0 Sigma-54 interaction domain AAA_14 PF13173.1 AIO01045.1 - 0.034 14.0 0.0 0.068 13.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain DUF2075 PF09848.4 AIO01045.1 - 0.054 12.4 0.1 0.09 11.7 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) NACHT PF05729.7 AIO01045.1 - 0.1 12.2 0.0 0.8 9.3 0.1 2.2 2 0 0 2 2 2 0 NACHT domain AAA_2 PF07724.9 AIO01045.1 - 0.12 12.3 0.4 1.5 8.7 0.2 2.6 1 1 1 2 2 2 0 AAA domain (Cdc48 subfamily) AAA_18 PF13238.1 AIO01045.1 - 0.13 12.6 0.0 0.36 11.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain YqaJ PF09588.5 AIO01046.1 - 1.3e-51 174.5 0.0 2.1e-51 173.9 0.0 1.3 1 0 0 1 1 1 1 YqaJ-like viral recombinase domain NUDIX PF00293.23 AIO01048.1 - 3.7e-10 39.5 0.1 1.3e-09 37.7 0.1 1.8 1 1 0 1 1 1 1 NUDIX domain PSP1 PF04468.7 AIO01049.1 - 1e-25 89.4 0.7 1.8e-25 88.7 0.5 1.4 1 0 0 1 1 1 1 PSP1 C-terminal conserved region DUF1556 PF07590.6 AIO01049.1 - 0.55 10.5 9.6 0.23 11.6 3.5 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1556) eIF3_p135 PF12807.2 AIO01050.1 - 3.1e-09 37.0 0.0 5.1e-09 36.3 0.0 1.3 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit 135 CLU PF13236.1 AIO01050.1 - 0.02 14.3 0.0 0.057 12.8 0.0 1.6 2 0 0 2 2 2 0 Clustered mitochondria ArfGap PF01412.13 AIO01051.1 - 1.7e-39 134.2 0.2 2.9e-39 133.4 0.1 1.4 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf PMI_typeI PF01238.16 AIO01052.1 - 5.6e-91 305.3 0.0 6.3e-91 305.1 0.0 1.0 1 0 0 1 1 1 1 Phosphomannose isomerase type I PIF1 PF05970.9 AIO01053.1 - 1.2e-37 129.7 1.1 2.5e-15 56.3 0.0 4.4 4 0 0 4 4 4 4 PIF1-like helicase AAA_30 PF13604.1 AIO01053.1 - 3.1e-09 36.7 3.8 7.1e-08 32.2 0.5 3.8 3 1 0 3 3 3 1 AAA domain AAA_19 PF13245.1 AIO01053.1 - 1.3e-05 24.8 0.8 0.00012 21.6 0.5 2.7 2 0 0 2 2 2 1 Part of AAA domain AAA_22 PF13401.1 AIO01053.1 - 0.0016 18.6 0.0 0.038 14.1 0.0 2.6 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.9 AIO01053.1 - 0.0017 18.1 0.2 0.069 12.8 0.0 2.7 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.12 AIO01053.1 - 0.0039 16.6 1.5 0.74 9.2 0.1 3.2 3 0 0 3 3 3 1 IstB-like ATP binding protein AAA_16 PF13191.1 AIO01053.1 - 0.0049 16.8 0.9 0.023 14.7 0.1 2.3 2 0 0 2 2 2 1 AAA ATPase domain NTPase_1 PF03266.10 AIO01053.1 - 0.0061 16.2 0.1 0.58 9.8 0.0 2.3 2 0 0 2 2 2 1 NTPase UvrD_C_2 PF13538.1 AIO01053.1 - 0.0073 16.4 0.0 0.046 13.8 0.0 2.3 2 0 0 2 2 2 1 UvrD-like helicase C-terminal domain DUF87 PF01935.12 AIO01053.1 - 0.014 15.2 0.1 0.032 14.0 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function DUF87 PhoH PF02562.11 AIO01053.1 - 0.016 14.4 0.0 0.031 13.4 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein Viral_helicase1 PF01443.13 AIO01053.1 - 0.017 14.6 0.2 4.8 6.6 0.0 3.5 3 0 0 3 3 3 0 Viral (Superfamily 1) RNA helicase AAA PF00004.24 AIO01053.1 - 0.024 14.8 0.0 0.28 11.3 0.0 2.7 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Helicase_RecD PF05127.9 AIO01053.1 - 0.034 13.8 1.7 0.7 9.5 1.2 2.6 1 1 0 1 1 1 0 Helicase DUF815 PF05673.8 AIO01053.1 - 0.039 12.8 0.0 0.067 12.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Herpes_Helicase PF02689.9 AIO01053.1 - 0.044 11.5 3.7 1.4 6.6 0.3 2.5 3 0 0 3 3 3 0 Helicase AAA_10 PF12846.2 AIO01053.1 - 0.046 13.1 0.0 0.093 12.1 0.0 1.5 1 0 0 1 1 1 0 AAA-like domain NACHT PF05729.7 AIO01053.1 - 0.06 12.9 0.0 0.14 11.7 0.0 1.6 1 0 0 1 1 1 0 NACHT domain AAA_25 PF13481.1 AIO01053.1 - 0.098 12.0 0.4 1.2 8.4 0.2 2.4 2 0 0 2 2 2 0 AAA domain MobB PF03205.9 AIO01053.1 - 0.13 11.9 0.0 0.34 10.5 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B C_GCAxxG_C_C PF09719.5 AIO01056.1 - 0.033 13.9 0.1 0.033 13.9 0.1 2.0 2 0 0 2 2 2 0 Putative redox-active protein (C_GCAxxG_C_C) NAD_synthase PF02540.12 AIO01061.1 - 1.7e-33 115.4 0.0 2.1e-33 115.2 0.0 1.0 1 0 0 1 1 1 1 NAD synthase Met_asp_mut_E PF06368.6 AIO01061.1 - 0.01 14.0 0.0 0.047 11.8 0.0 1.7 1 1 1 2 2 2 0 Methylaspartate mutase E chain (MutE) Asn_synthase PF00733.16 AIO01061.1 - 0.1 12.1 0.0 0.14 11.6 0.0 1.2 1 0 0 1 1 1 0 Asparagine synthase PP2C PF00481.16 AIO01063.1 - 7.3e-68 228.7 0.0 1e-67 228.2 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.1 AIO01063.1 - 0.016 14.6 0.0 0.047 13.0 0.0 1.9 1 1 0 1 1 1 0 Protein phosphatase 2C SpoIIE PF07228.7 AIO01063.1 - 0.14 11.8 0.0 1 9.0 0.0 2.0 1 1 0 1 1 1 0 Stage II sporulation protein E (SpoIIE) SpoU_methylase PF00588.14 AIO01065.1 - 5.9e-12 45.6 0.0 0.014 15.2 0.0 4.0 4 0 0 4 4 4 3 SpoU rRNA Methylase family DNA_pol_E_B PF04042.11 AIO01066.1 - 1.3e-12 47.4 0.1 2.3e-11 43.3 0.0 2.2 2 0 0 2 2 2 2 DNA polymerase alpha/epsilon subunit B Coatomer_E PF04733.9 AIO01067.1 - 3e-30 105.4 5.1 1.1e-22 80.5 1.6 2.0 2 0 0 2 2 2 2 Coatomer epsilon subunit TPR_11 PF13414.1 AIO01067.1 - 2.3e-05 23.9 7.4 7.6e-05 22.2 1.4 3.8 3 1 1 4 4 4 1 TPR repeat TPR_2 PF07719.12 AIO01067.1 - 2.9e-05 23.6 4.3 0.62 10.1 0.0 5.9 5 1 1 6 6 6 1 Tetratricopeptide repeat TPR_19 PF14559.1 AIO01067.1 - 4.2e-05 23.7 13.9 0.015 15.6 0.2 4.2 4 1 1 5 5 4 2 Tetratricopeptide repeat TPR_14 PF13428.1 AIO01067.1 - 0.00019 21.7 14.3 0.52 11.0 0.8 5.5 3 2 2 5 5 5 2 Tetratricopeptide repeat TPR_12 PF13424.1 AIO01067.1 - 0.00095 19.0 12.5 0.0023 17.8 2.2 4.4 4 2 1 5 5 5 1 Tetratricopeptide repeat TPR_16 PF13432.1 AIO01067.1 - 0.0035 17.9 16.8 0.026 15.2 2.1 4.8 2 1 4 6 6 6 3 Tetratricopeptide repeat TPR_1 PF00515.23 AIO01067.1 - 0.014 14.9 4.9 0.43 10.2 0.0 4.9 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_4 PF07721.9 AIO01067.1 - 0.03 14.7 3.2 2.6 8.7 0.1 4.4 3 0 0 3 3 3 0 Tetratricopeptide repeat Apc3 PF12895.2 AIO01067.1 - 0.039 14.0 4.0 0.54 10.4 0.0 3.5 3 2 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_10 PF13374.1 AIO01067.1 - 0.042 13.8 6.8 1.3 9.0 0.0 4.0 4 0 0 4 4 3 0 Tetratricopeptide repeat TPR_8 PF13181.1 AIO01067.1 - 0.06 13.1 3.6 2.9 7.8 0.0 4.5 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_7 PF13176.1 AIO01067.1 - 6.8 6.7 6.2 20 5.2 0.1 4.5 6 0 0 6 6 6 0 Tetratricopeptide repeat WW PF00397.21 AIO01068.1 - 4.1e-11 42.5 0.8 6.2e-11 41.9 0.6 1.3 1 0 0 1 1 1 1 WW domain zf-CCCH PF00642.19 AIO01068.1 - 1.5e-06 27.7 0.6 3.1e-06 26.7 0.4 1.6 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.1 AIO01068.1 - 0.011 15.7 0.2 0.023 14.6 0.2 1.6 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type PUF PF00806.14 AIO01069.1 - 2e-19 67.8 0.0 0.041 13.3 0.0 8.8 10 0 0 10 10 10 6 Pumilio-family RNA binding repeat CobU PF02283.11 AIO01070.1 - 0.019 14.3 1.1 0.044 13.2 0.8 1.6 1 0 0 1 1 1 0 Cobinamide kinase / cobinamide phosphate guanyltransferase PBP PF01161.15 AIO01071.1 - 1.8e-06 27.8 0.1 3.7e-06 26.8 0.1 1.5 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein TFIIA PF03153.8 AIO01074.1 - 0.015 15.1 5.1 0.021 14.7 3.5 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit CDC45 PF02724.9 AIO01074.1 - 0.18 9.7 4.6 0.21 9.5 3.2 1.3 1 0 0 1 1 1 0 CDC45-like protein Pkinase PF00069.20 AIO01076.1 - 2.8e-45 154.5 0.0 2.1e-44 151.6 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AIO01076.1 - 1.8e-30 105.8 0.0 7.4e-30 103.8 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase PH PF00169.24 AIO01076.1 - 3.2e-07 30.4 0.0 6.8e-07 29.4 0.0 1.6 1 0 0 1 1 1 1 PH domain Kinase-like PF14531.1 AIO01076.1 - 0.00019 20.5 0.0 0.00031 19.7 0.0 1.2 1 0 0 1 1 1 1 Kinase-like PH_9 PF15410.1 AIO01076.1 - 0.0086 16.2 0.0 0.021 15.0 0.0 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain Sod_Fe_C PF02777.13 AIO01077.1 - 9.8e-41 137.8 0.6 1.6e-40 137.1 0.2 1.5 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.17 AIO01077.1 - 5.3e-21 74.6 0.3 1.9e-20 72.9 0.0 1.8 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, alpha-hairpin domain Peptidase_M3_N PF08439.5 AIO01077.1 - 0.12 12.4 0.1 1.6 8.8 0.0 2.2 2 0 0 2 2 2 0 Oligopeptidase F Ras PF00071.17 AIO01078.1 - 2.9e-36 124.3 0.0 3.5e-36 124.0 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 AIO01078.1 - 1.6e-17 64.0 0.0 2.5e-17 63.4 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 AIO01078.1 - 3e-10 39.6 0.0 4e-10 39.2 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 AIO01078.1 - 9.2e-08 31.5 0.0 1.1e-07 31.2 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 AIO01078.1 - 1.5e-07 31.0 0.0 1.2e-05 24.8 0.0 2.8 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain SRPRB PF09439.5 AIO01078.1 - 1.1e-05 24.7 0.0 2e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.18 AIO01078.1 - 4.8e-05 23.2 0.0 7.8e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase ATP_bind_1 PF03029.12 AIO01078.1 - 0.00031 20.3 0.1 0.00051 19.6 0.0 1.4 1 1 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_22 PF13401.1 AIO01078.1 - 0.088 12.9 0.0 0.51 10.4 0.0 2.1 1 1 1 2 2 2 0 AAA domain Cpn60_TCP1 PF00118.19 AIO01079.1 - 3.4e-119 398.6 3.0 4.3e-119 398.2 2.1 1.1 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family DOR PF14839.1 AIO01080.1 - 0.13 11.9 0.1 0.25 11.0 0.1 1.4 1 0 0 1 1 1 0 DOR family Cation_efflux PF01545.16 AIO01081.1 - 4.2e-51 173.7 7.9 5.4e-51 173.3 5.5 1.1 1 0 0 1 1 1 1 Cation efflux family CBFD_NFYB_HMF PF00808.18 AIO01082.1 - 0.0021 18.0 0.0 0.0033 17.4 0.0 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone DUF647 PF04884.9 AIO01086.1 - 1.2e-18 67.2 7.3 2e-18 66.5 5.0 1.2 1 0 0 1 1 1 1 Vitamin B6 photo-protection and homoeostasis AviRa PF11599.3 AIO01087.1 - 0.035 13.1 0.1 0.066 12.2 0.1 1.4 1 0 0 1 1 1 0 RRNA methyltransferase AviRa GED PF02212.13 AIO01087.1 - 6.4 6.7 7.8 3 7.8 1.9 2.6 2 0 0 2 2 2 0 Dynamin GTPase effector domain CTDII PF01556.13 AIO01088.1 - 7.3e-26 89.8 0.0 3.9e-20 71.5 0.0 2.4 2 0 0 2 2 2 2 DnaJ C terminal domain DnaJ PF00226.26 AIO01088.1 - 4.8e-16 58.2 0.4 7.1e-16 57.6 0.3 1.3 1 0 0 1 1 1 1 DnaJ domain Acyltransferase PF01553.16 AIO01090.1 - 1.1e-15 57.1 0.1 4.2e-15 55.3 0.0 1.8 2 0 0 2 2 2 1 Acyltransferase DUF367 PF04034.8 AIO01092.1 - 3.4e-48 162.4 0.0 4.4e-48 162.0 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF367) RLI PF04068.10 AIO01092.1 - 6.5e-11 41.6 0.0 1.2e-10 40.7 0.0 1.4 1 0 0 1 1 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI Evr1_Alr PF04777.8 AIO01093.1 - 0.13 12.2 0.4 0.21 11.5 0.3 1.5 1 0 0 1 1 1 0 Erv1 / Alr family Nop25 PF09805.4 AIO01093.1 - 0.14 12.1 3.6 0.18 11.8 2.5 1.2 1 0 0 1 1 1 0 Nucleolar protein 12 (25kDa) DUF4615 PF15393.1 AIO01093.1 - 0.46 10.7 2.4 0.55 10.4 1.6 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4615) DUF4200 PF13863.1 AIO01094.1 - 5.9e-25 87.6 13.1 5.9e-25 87.6 9.1 3.8 4 1 0 4 4 4 1 Domain of unknown function (DUF4200) GP41 PF00517.12 AIO01094.1 - 0.18 11.3 2.1 8.5 5.8 0.3 2.7 2 0 0 2 2 2 0 Retroviral envelope protein Occludin_ELL PF07303.8 AIO01094.1 - 0.33 11.7 0.1 0.33 11.7 0.1 3.2 3 0 0 3 3 3 0 Occludin homology domain TMF_DNA_bd PF12329.3 AIO01094.1 - 0.7 9.7 21.2 5 7.0 0.4 5.2 4 0 0 4 4 4 0 TATA element modulatory factor 1 DNA binding FlaC_arch PF05377.6 AIO01094.1 - 3.2 7.7 7.6 9.3 6.2 0.2 4.0 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) Endosulfine PF04667.12 AIO01095.1 - 2.3e-05 24.2 4.0 4.5e-05 23.3 2.7 1.7 1 1 0 1 1 1 1 cAMP-regulated phosphoprotein/endosulfine conserved region DUF3456 PF11938.3 AIO01096.1 - 1.1e-10 41.7 8.8 4e-10 39.8 3.1 2.9 1 1 1 2 2 2 1 TLR4 regulator and MIR-interacting MSAP Kri1 PF05178.7 AIO01096.1 - 0.084 13.1 1.3 1.2 9.4 0.1 2.6 3 0 0 3 3 3 0 KRI1-like family DUF4378 PF14309.1 AIO01096.1 - 0.21 11.6 1.7 0.23 11.5 0.1 1.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4378) DUF3123 PF11321.3 AIO01096.1 - 3.9 7.7 7.7 54 4.1 3.3 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF3123) DUF2664 PF10867.3 AIO01096.1 - 8.6 7.0 8.3 2.5 8.8 0.1 3.3 3 2 0 3 3 3 0 Protein of unknown function (DUF2664) MIR PF02815.14 AIO01097.1 - 0.0025 17.3 0.0 0.0057 16.1 0.0 1.5 2 0 0 2 2 2 1 MIR domain EMP24_GP25L PF01105.19 AIO01098.1 - 2.2e-31 109.0 0.1 2.4e-31 108.8 0.0 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Ras PF00071.17 AIO01099.1 - 5.9e-61 204.5 0.0 7e-61 204.3 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 AIO01099.1 - 2e-18 66.9 0.0 3.1e-18 66.4 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 AIO01099.1 - 3.2e-12 46.0 0.0 3.9e-12 45.7 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 AIO01099.1 - 0.00012 21.2 0.0 0.00017 20.8 0.0 1.3 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 AIO01099.1 - 0.00032 20.1 0.0 0.0013 18.1 0.0 1.8 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 AIO01099.1 - 0.00061 19.7 0.0 0.0009 19.1 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_24 PF13479.1 AIO01099.1 - 0.023 14.2 0.0 0.036 13.6 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.1 AIO01099.1 - 0.029 14.4 0.0 0.064 13.3 0.0 1.9 1 1 0 1 1 1 0 AAA domain DUF258 PF03193.11 AIO01099.1 - 0.03 13.5 0.0 0.081 12.1 0.0 1.7 1 1 1 2 2 2 0 Protein of unknown function, DUF258 AAA_16 PF13191.1 AIO01099.1 - 0.066 13.1 0.1 0.11 12.4 0.1 1.6 1 1 0 1 1 1 0 AAA ATPase domain DUF3234 PF11572.3 AIO01099.1 - 0.11 12.6 0.0 0.19 11.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3234) ABC_tran PF00005.22 AIO01102.1 - 8e-18 65.0 0.0 1.6e-17 64.0 0.0 1.6 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 AIO01102.1 - 2.1e-11 44.3 0.1 1.4e-06 28.4 0.2 2.2 2 0 0 2 2 2 2 AAA domain SMC_N PF02463.14 AIO01102.1 - 2.7e-08 33.3 0.0 3.5e-06 26.4 0.0 2.2 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_15 PF13175.1 AIO01102.1 - 0.00021 20.4 0.0 0.001 18.1 0.0 1.8 2 0 0 2 2 2 1 AAA ATPase domain AAA_16 PF13191.1 AIO01102.1 - 0.00023 21.1 1.0 0.0013 18.7 0.7 2.3 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 AIO01102.1 - 0.00078 19.5 0.3 0.01 16.0 0.0 2.6 3 0 0 3 3 3 1 AAA domain DUF258 PF03193.11 AIO01102.1 - 0.0019 17.4 0.1 0.0047 16.1 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_23 PF13476.1 AIO01102.1 - 0.0025 18.1 0.0 0.0041 17.4 0.0 1.2 1 0 0 1 1 1 1 AAA domain SbcCD_C PF13558.1 AIO01102.1 - 0.0029 17.5 0.0 0.023 14.5 0.0 2.5 2 0 0 2 2 2 1 Putative exonuclease SbcCD, C subunit ABC_membrane PF00664.18 AIO01102.1 - 0.0086 15.5 12.9 0.017 14.5 8.9 1.6 1 1 0 1 1 1 1 ABC transporter transmembrane region AAA_13 PF13166.1 AIO01102.1 - 0.0094 14.4 0.0 1.4 7.2 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.1 AIO01102.1 - 0.012 15.0 0.2 0.056 12.8 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA PF00004.24 AIO01102.1 - 0.016 15.3 0.1 0.12 12.6 0.0 2.4 3 0 0 3 3 2 0 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.1 AIO01102.1 - 0.017 14.6 0.1 0.037 13.5 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain DASH_Dam1 PF08653.5 AIO01102.1 - 0.029 14.1 0.0 0.11 12.2 0.0 2.1 1 0 0 1 1 1 0 DASH complex subunit Dam1 RNA_helicase PF00910.17 AIO01102.1 - 0.036 14.2 0.0 0.071 13.2 0.0 1.5 1 0 0 1 1 1 0 RNA helicase Adeno_IVa2 PF02456.10 AIO01102.1 - 0.038 12.6 0.0 0.061 11.9 0.0 1.3 1 0 0 1 1 1 0 Adenovirus IVa2 protein Arch_ATPase PF01637.13 AIO01102.1 - 0.094 12.4 0.0 0.2 11.2 0.0 1.5 1 0 0 1 1 1 0 Archaeal ATPase AAA_5 PF07728.9 AIO01102.1 - 0.11 12.2 0.1 0.21 11.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_17 PF13207.1 AIO01102.1 - 0.15 12.9 0.1 0.4 11.5 0.0 1.7 2 0 0 2 2 1 0 AAA domain Rad17 PF03215.10 AIO01102.1 - 0.18 10.4 0.8 0.28 9.8 0.5 1.2 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein AAA_19 PF13245.1 AIO01102.1 - 0.33 10.7 3.9 0.53 10.0 0.1 3.3 3 0 0 3 3 3 0 Part of AAA domain CTP_transf_2 PF01467.21 AIO01103.1 - 3.4e-09 36.9 0.0 5.6e-09 36.2 0.0 1.4 1 0 0 1 1 1 1 Cytidylyltransferase dCMP_cyt_deam_1 PF00383.17 AIO01104.1 - 1.8e-07 30.7 0.0 3.6e-07 29.7 0.0 1.6 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region Bd3614-deam PF14439.1 AIO01104.1 - 0.0087 15.9 0.1 0.056 13.2 0.0 2.3 2 0 0 2 2 2 1 Bd3614-like deaminase Methyltransf_26 PF13659.1 AIO01105.1 - 1.6e-15 57.1 0.1 3.3e-15 56.1 0.1 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 AIO01105.1 - 0.00079 19.0 0.0 0.28 10.7 0.0 2.3 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_25 PF13649.1 AIO01105.1 - 0.014 15.7 0.0 0.19 12.0 0.0 2.6 1 1 0 1 1 1 0 Methyltransferase domain Cons_hypoth95 PF03602.10 AIO01105.1 - 0.14 11.5 0.0 0.55 9.6 0.0 1.9 2 0 0 2 2 2 0 Conserved hypothetical protein 95 KLRAQ PF10205.4 AIO01106.1 - 0.042 13.8 0.1 0.042 13.8 0.1 4.0 3 1 2 5 5 5 0 Predicted coiled-coil domain-containing protein Tropomyosin_1 PF12718.2 AIO01106.1 - 0.058 13.2 18.2 2.3 8.0 0.3 3.5 3 0 0 3 3 3 0 Tropomyosin like MbeD_MobD PF04899.7 AIO01106.1 - 0.094 12.6 6.0 0.055 13.3 1.3 2.7 2 0 0 2 2 2 0 MbeD/MobD like CDC37_N PF03234.9 AIO01106.1 - 3.9 7.7 7.3 11 6.3 5.0 1.7 1 0 0 1 1 1 0 Cdc37 N terminal kinase binding RRM_1 PF00076.17 AIO01109.1 - 1e-06 28.2 0.0 1.9e-06 27.4 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 AIO01109.1 - 6.8e-05 22.7 0.0 0.00014 21.7 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) CSTF2_hinge PF14327.1 AIO01109.1 - 0.00022 21.2 0.1 0.00022 21.2 0.0 2.3 3 0 0 3 3 3 1 Hinge domain of cleavage stimulation factor subunit 2 RRM_5 PF13893.1 AIO01109.1 - 0.026 14.3 0.0 0.054 13.3 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) HEAT_EZ PF13513.1 AIO01111.1 - 2.1e-11 43.9 3.6 0.26 11.8 0.0 7.3 6 1 1 7 7 7 4 HEAT-like repeat HEAT PF02985.17 AIO01111.1 - 7.7e-08 31.7 8.2 0.094 12.8 0.0 7.3 7 0 0 7 7 7 2 HEAT repeat HEAT_2 PF13646.1 AIO01111.1 - 8.2e-07 29.2 2.6 0.00098 19.3 0.1 4.7 3 1 0 4 4 4 1 HEAT repeats Cnd1 PF12717.2 AIO01111.1 - 0.00079 19.3 0.1 0.0047 16.7 0.0 2.3 2 0 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 RIX1 PF08167.7 AIO01111.1 - 0.012 15.3 7.2 17 5.0 0.0 5.6 6 1 0 6 6 6 0 rRNA processing/ribosome biogenesis Utp12 PF04003.7 AIO01111.1 - 0.069 13.0 1.2 1.2 9.0 0.0 3.4 4 0 0 4 4 4 0 Dip2/Utp12 Family Adaptin_N PF01602.15 AIO01111.1 - 0.93 7.7 5.2 1.8 6.7 0.0 3.6 4 1 0 4 4 4 0 Adaptin N terminal region Synaptobrevin PF00957.16 AIO01113.1 - 5.3e-09 35.5 4.2 1.1e-08 34.5 2.9 1.4 1 0 0 1 1 1 1 Synaptobrevin EcoR124_C PF12008.3 AIO01113.1 - 0.26 10.4 0.9 0.41 9.7 0.6 1.2 1 0 0 1 1 1 0 Type I restriction and modification enzyme - subunit R C terminal PCI_Csn8 PF10075.4 AIO01115.1 - 1.4e-14 54.0 0.0 2.6e-14 53.2 0.0 1.4 1 0 0 1 1 1 1 COP9 signalosome, subunit CSN8 SAC3_GANP PF03399.11 AIO01115.1 - 1.1e-11 44.6 0.0 1.5e-11 44.2 0.0 1.2 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family PCI PF01399.22 AIO01115.1 - 0.0033 17.7 0.1 0.0049 17.1 0.1 1.4 1 1 0 1 1 1 1 PCI domain DUF3378 PF11858.3 AIO01115.1 - 0.1 12.6 0.0 0.17 11.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3378) GTP_EFTU PF00009.22 AIO01117.1 - 1.4e-25 89.8 0.0 2.1e-25 89.2 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.19 AIO01117.1 - 1.3e-14 53.7 0.0 2.9e-14 52.6 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G C-terminus Miro PF08477.8 AIO01117.1 - 1e-08 35.6 0.0 2.1e-08 34.6 0.0 1.5 1 0 0 1 1 1 1 Miro-like protein EFG_II PF14492.1 AIO01117.1 - 7.2e-08 32.1 0.0 1.6e-07 31.1 0.0 1.5 1 0 0 1 1 1 1 Elongation Factor G, domain II MMR_HSR1 PF01926.18 AIO01117.1 - 9.6e-07 28.7 0.0 2.2e-06 27.5 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.18 AIO01117.1 - 1.1e-06 28.6 0.2 0.028 14.2 0.0 2.5 1 1 1 2 2 2 2 Dynamin family EFG_IV PF03764.13 AIO01117.1 - 5.6e-05 22.6 0.0 0.00012 21.6 0.0 1.5 1 0 0 1 1 1 1 Elongation factor G, domain IV Septin PF00735.13 AIO01117.1 - 0.00049 19.2 0.0 0.00079 18.5 0.0 1.2 1 0 0 1 1 1 1 Septin SRPRB PF09439.5 AIO01117.1 - 0.0022 17.2 0.0 0.0037 16.4 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.17 AIO01117.1 - 0.0052 16.1 0.0 0.01 15.2 0.0 1.4 1 0 0 1 1 1 1 Ras family AIG1 PF04548.11 AIO01117.1 - 0.03 13.4 0.1 0.25 10.4 0.0 2.1 2 0 0 2 2 2 0 AIG1 family DUF258 PF03193.11 AIO01117.1 - 0.1 11.7 0.0 0.27 10.4 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function, DUF258 PduV-EutP PF10662.4 AIO01117.1 - 0.12 11.9 0.0 1.2 8.6 0.0 2.2 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Complex1_LYR PF05347.10 AIO01118.1 - 2.3e-11 43.3 0.6 2.3e-11 43.3 0.4 1.6 2 0 0 2 2 2 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 AIO01118.1 - 1.1e-09 38.4 3.0 1.1e-09 38.3 0.4 2.0 2 0 0 2 2 2 1 Complex1_LYR-like DUF2304 PF10066.4 AIO01118.1 - 0.12 12.1 0.0 0.28 11.0 0.0 1.6 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2304) DUF4238 PF14022.1 AIO01119.1 - 0.056 12.7 0.8 0.1 11.8 0.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4238) Spc7 PF08317.6 AIO01120.1 - 4.6e-05 22.2 10.9 4.6e-05 22.2 7.6 3.2 2 1 1 3 3 3 2 Spc7 kinetochore protein ATG16 PF08614.6 AIO01120.1 - 3.8 7.2 62.0 0.85 9.4 10.7 3.8 1 1 1 3 3 3 0 Autophagy protein 16 (ATG16) Pneumovirus_M2 PF06436.6 AIO01120.1 - 6.2 6.0 10.6 0.18 11.0 1.8 2.5 3 1 1 4 4 4 0 Pneumovirus matrix protein 2 (M2) DEAD PF00270.24 AIO01121.1 - 1.9e-39 134.8 0.0 4e-39 133.8 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 AIO01121.1 - 2.4e-21 75.3 0.0 6e-21 74.0 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF4217 PF13959.1 AIO01121.1 - 1.2e-13 50.4 0.1 3.1e-13 49.0 0.1 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.10 AIO01121.1 - 0.0074 16.1 0.0 0.016 15.0 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Formyl_trans_N PF00551.14 AIO01122.1 - 7.2e-15 54.9 0.0 1.4e-14 54.0 0.0 1.4 1 0 0 1 1 1 1 Formyl transferase CS PF04969.11 AIO01124.1 - 1e-05 25.9 0.0 1.9e-05 25.0 0.0 1.5 1 0 0 1 1 1 1 CS domain AD PF09793.4 AIO01125.1 - 0.13 12.0 0.1 0.24 11.2 0.0 1.3 1 0 0 1 1 1 0 Anticodon-binding domain KRE9 PF05390.6 AIO01127.1 - 0.012 15.9 1.1 0.028 14.7 0.7 1.7 1 0 0 1 1 1 0 Yeast cell wall synthesis protein KRE9/KNH1 PAP2 PF01569.16 AIO01128.1 - 2.3e-19 69.3 2.6 2.3e-19 69.3 1.8 2.5 2 1 0 2 2 2 1 PAP2 superfamily DivIC PF04977.10 AIO01129.1 - 0.31 10.5 2.9 0.56 9.7 2.0 1.4 1 0 0 1 1 1 0 Septum formation initiator ERG4_ERG24 PF01222.12 AIO01131.1 - 3.4e-124 414.6 1.8 3.9e-124 414.4 1.2 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF1295 PF06966.7 AIO01131.1 - 1.7e-07 30.7 0.1 4e-07 29.5 0.1 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) PEMT PF04191.8 AIO01131.1 - 3.1e-05 24.0 0.0 0.00012 22.1 0.0 2.0 1 0 0 1 1 1 1 Phospholipid methyltransferase ICMT PF04140.9 AIO01131.1 - 0.0034 17.5 4.8 0.0037 17.4 0.0 3.1 3 0 0 3 3 3 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family EamA PF00892.15 AIO01132.1 - 0.00039 20.4 10.1 0.00061 19.8 7.0 1.4 1 1 0 1 1 1 1 EamA-like transporter family TPT PF03151.11 AIO01132.1 - 0.048 13.3 7.3 0.063 12.9 5.0 1.4 1 1 0 1 1 1 0 Triose-phosphate Transporter family UPF0546 PF10639.4 AIO01132.1 - 0.053 13.3 2.6 0.065 13.0 1.8 1.2 1 0 0 1 1 1 0 Uncharacterised protein family UPF0546 Tmemb_18A PF09771.4 AIO01132.1 - 0.082 12.8 2.3 0.093 12.7 1.2 1.4 1 1 0 1 1 1 0 Transmembrane protein 188 EmrE PF13536.1 AIO01132.1 - 0.22 11.7 5.7 0.37 11.0 4.0 1.4 1 0 0 1 1 1 0 Multidrug resistance efflux transporter NAD_binding_1 PF00175.16 AIO01133.1 - 1.2e-16 61.2 0.0 3e-11 43.8 0.0 2.4 1 1 1 2 2 2 2 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 AIO01133.1 - 8.3e-11 41.8 0.0 1.5e-10 41.0 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.7 AIO01133.1 - 0.00017 21.4 0.0 0.0003 20.7 0.0 1.4 1 1 0 1 1 1 1 Ferric reductase NAD binding domain Nsp1_C PF05064.8 AIO01134.1 - 5.9e-08 32.3 0.2 9.5e-08 31.6 0.1 1.2 1 0 0 1 1 1 1 Nsp1-like C-terminal region Myosin_tail_1 PF01576.14 AIO01134.1 - 0.012 13.3 1.1 0.017 12.8 0.7 1.1 1 0 0 1 1 1 0 Myosin tail PPR_3 PF13812.1 AIO01135.1 - 0.028 14.7 0.3 75 4.0 0.0 4.7 4 0 0 4 4 4 0 Pentatricopeptide repeat domain MIP PF00230.15 AIO01136.1 - 5.5e-31 107.8 17.7 6.7e-31 107.5 12.3 1.1 1 0 0 1 1 1 1 Major intrinsic protein DUF3353 PF11833.3 AIO01136.1 - 0.88 8.9 6.7 0.84 9.0 0.9 2.3 1 1 0 2 2 2 0 Protein of unknown function (DUF3353) DUF202 PF02656.10 AIO01136.1 - 1 9.6 8.9 25 5.1 2.5 3.5 1 1 1 2 2 2 0 Domain of unknown function (DUF202) NfeD PF01957.13 AIO01136.1 - 7.4 6.7 10.5 0.91 9.6 0.5 2.9 1 1 2 3 3 3 0 NfeD-like C-terminal, partner-binding MIP PF00230.15 AIO01137.1 - 3.5e-30 105.1 16.5 4.6e-30 104.7 11.4 1.1 1 0 0 1 1 1 1 Major intrinsic protein DNA_pol_lambd_f PF10391.4 AIO01139.1 - 0.049 13.1 0.0 0.098 12.2 0.0 1.4 1 0 0 1 1 1 0 Fingers domain of DNA polymerase lambda TPR_12 PF13424.1 AIO01140.1 - 1.1e-06 28.4 3.9 1.1e-06 28.4 2.7 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.1 AIO01140.1 - 0.00013 21.5 8.8 0.00018 21.1 1.4 3.3 3 0 0 3 3 3 1 TPR repeat MIT PF04212.13 AIO01140.1 - 0.0048 16.7 0.7 0.0048 16.7 0.5 2.5 3 0 0 3 3 3 1 MIT (microtubule interacting and transport) domain TPR_1 PF00515.23 AIO01140.1 - 0.17 11.5 11.3 3.8 7.2 0.2 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat Nol1_Nop2_Fmu PF01189.12 AIO01142.1 - 1e-23 84.1 0.0 1.5e-23 83.5 0.0 1.2 1 0 0 1 1 1 1 NOL1/NOP2/sun family Methyltransf_26 PF13659.1 AIO01142.1 - 0.0013 18.7 0.1 0.0022 18.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 AIO01142.1 - 0.014 15.9 0.0 0.026 15.1 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain FtsJ PF01728.14 AIO01142.1 - 0.14 12.1 0.0 0.21 11.5 0.0 1.4 1 0 0 1 1 1 0 FtsJ-like methyltransferase NUDIX PF00293.23 AIO01143.1 - 1.9e-06 27.5 0.0 6.1e-06 25.9 0.0 1.8 1 1 0 1 1 1 1 NUDIX domain MNSV_P7B PF06692.6 AIO01143.1 - 0.084 12.6 0.0 0.17 11.7 0.0 1.4 1 0 0 1 1 1 0 Melon necrotic spot virus P7B protein PAP_assoc PF03828.14 AIO01144.1 - 3.6e-08 33.2 0.0 6.9e-08 32.3 0.0 1.5 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.18 AIO01144.1 - 0.0005 20.3 0.0 0.001 19.3 0.0 1.5 1 0 0 1 1 1 1 Nucleotidyltransferase domain ubiquitin PF00240.18 AIO01146.1 - 0.013 14.8 0.0 0.019 14.3 0.0 1.2 1 0 0 1 1 1 0 Ubiquitin family TPR_14 PF13428.1 AIO01147.1 - 0.00011 22.4 41.3 0.33 11.7 1.3 11.6 10 1 2 12 12 12 2 Tetratricopeptide repeat TPR_2 PF07719.12 AIO01147.1 - 0.00012 21.6 5.7 0.0039 16.9 1.2 4.8 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_11 PF13414.1 AIO01147.1 - 0.00058 19.4 12.1 0.15 11.7 0.5 5.1 5 1 1 6 6 6 2 TPR repeat Apc3 PF12895.2 AIO01147.1 - 0.002 18.2 0.9 0.69 10.0 0.1 3.6 3 0 0 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 PRP1_N PF06424.7 AIO01147.1 - 0.0046 17.2 0.2 0.0088 16.3 0.2 1.4 1 0 0 1 1 1 1 PRP1 splicing factor, N-terminal TPR_17 PF13431.1 AIO01147.1 - 0.04 14.1 5.5 7.1 7.1 0.0 5.2 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_1 PF00515.23 AIO01147.1 - 0.058 13.0 1.2 0.32 10.6 0.8 2.4 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_12 PF13424.1 AIO01147.1 - 0.41 10.6 11.1 0.15 11.9 0.8 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_4 PF07721.9 AIO01147.1 - 3.1 8.5 12.2 5.4 7.7 0.5 4.6 3 1 1 4 4 4 0 Tetratricopeptide repeat cNMP_binding PF00027.24 AIO01152.1 - 2e-13 49.9 0.0 8.3e-06 25.5 0.0 3.5 3 0 0 3 3 3 3 Cyclic nucleotide-binding domain HD PF01966.17 AIO01153.1 - 2.2e-07 30.9 0.0 5.9e-07 29.5 0.0 1.9 1 0 0 1 1 1 1 HD domain A_deaminase PF00962.17 AIO01154.1 - 1.3e-80 270.8 0.4 1.5e-60 204.9 0.1 2.2 2 0 0 2 2 2 2 Adenosine/AMP deaminase DUF1192 PF06698.6 AIO01154.1 - 0.054 13.3 0.8 0.15 11.8 0.6 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1192) DUF4530 PF15039.1 AIO01154.1 - 0.065 13.1 0.1 0.2 11.5 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4530) Ctr PF04145.10 AIO01155.1 - 0.0012 18.9 0.1 0.23 11.5 0.0 2.4 2 0 0 2 2 2 2 Ctr copper transporter family IKKbetaNEMObind PF12179.3 AIO01156.1 - 0.098 12.4 0.2 0.26 11.1 0.2 1.7 1 0 0 1 1 1 0 I-kappa-kinase-beta NEMO binding domain WD40 PF00400.27 AIO01157.1 - 0.00031 20.4 2.0 3.2 7.7 0.0 4.6 5 0 0 5 5 5 3 WD domain, G-beta repeat CHCH PF06747.8 AIO01158.1 - 0.0036 17.1 3.6 0.0055 16.5 2.5 1.3 1 0 0 1 1 1 1 CHCH domain Colipase-like PF15083.1 AIO01158.1 - 0.0044 16.9 1.1 0.0065 16.3 0.7 1.3 1 0 0 1 1 1 1 Colipase-like DUF1903 PF08991.5 AIO01158.1 - 0.036 14.2 1.6 0.076 13.1 1.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1903) Complex1_LYR_2 PF13233.1 AIO01161.1 - 2.6e-11 43.8 0.1 4.7e-11 43.1 0.0 1.5 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.10 AIO01161.1 - 0.0034 17.1 0.8 0.0099 15.6 0.6 1.7 1 1 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 AIO01161.1 - 0.011 15.8 0.7 0.029 14.5 0.5 1.7 1 1 0 1 1 1 0 Complex1_LYR-like Sod_Fe_C PF02777.13 AIO01162.1 - 7.8e-32 109.2 1.3 2e-31 107.9 0.9 1.7 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.17 AIO01162.1 - 4.8e-19 68.4 0.4 4.8e-19 68.4 0.3 1.9 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, alpha-hairpin domain Cys_Met_Meta_PP PF01053.15 AIO01163.1 - 3.6e-84 282.2 0.0 4.2e-84 282.0 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.14 AIO01163.1 - 0.073 11.7 0.0 0.1 11.3 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class-V SpoU_methylase PF00588.14 AIO01164.1 - 9.2e-27 93.6 0.1 3.7e-23 81.9 0.0 4.0 4 0 0 4 4 4 2 SpoU rRNA Methylase family DUF1180 PF06679.7 AIO01164.1 - 1.4 8.7 6.6 1.4 8.7 0.4 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF1180) Aa_trans PF01490.13 AIO01165.1 - 1.5e-51 175.2 28.8 1.8e-51 174.9 19.9 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.8 AIO01165.1 - 2.2e-10 39.9 12.6 5.5e-10 38.6 8.6 1.8 1 1 0 1 1 1 1 Tryptophan/tyrosine permease family AA_permease_2 PF13520.1 AIO01165.1 - 0.00034 19.2 20.0 0.00034 19.2 13.8 2.2 1 1 1 2 2 2 1 Amino acid permease DUF3138 PF11336.3 AIO01166.1 - 0.71 7.9 3.8 1.2 7.2 2.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) Ribosomal_L27e PF01777.13 AIO01168.1 - 4.8e-27 93.8 1.5 6.5e-27 93.4 1.0 1.2 1 0 0 1 1 1 1 Ribosomal L27e protein family KOW PF00467.24 AIO01168.1 - 7e-06 25.5 0.1 2e-05 24.1 0.1 1.8 1 0 0 1 1 1 1 KOW motif Ribosomal_L27e PF01777.13 AIO01170.1 - 4.8e-27 93.8 1.5 6.5e-27 93.4 1.0 1.2 1 0 0 1 1 1 1 Ribosomal L27e protein family KOW PF00467.24 AIO01170.1 - 7e-06 25.5 0.1 2e-05 24.1 0.1 1.8 1 0 0 1 1 1 1 KOW motif Sybindin PF04099.7 AIO01171.1 - 4.8e-22 78.1 0.0 5.6e-22 77.9 0.0 1.0 1 0 0 1 1 1 1 Sybindin-like family Sedlin_N PF04628.8 AIO01171.1 - 3.7e-09 36.5 0.0 3.8e-09 36.5 0.0 1.1 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Rhodanese PF00581.15 AIO01173.1 - 7.7e-09 35.8 0.0 9.3e-09 35.6 0.0 1.1 1 0 0 1 1 1 1 Rhodanese-like domain Sec7 PF01369.15 AIO01174.1 - 6.9e-28 97.6 0.0 1.1e-27 96.9 0.0 1.3 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.2 AIO01174.1 - 7.5e-16 58.0 0.1 1.4e-15 57.1 0.1 1.4 1 0 0 1 1 1 1 Guanine nucleotide exchange factor in Golgi transport N-terminal Myc_target_1 PF15179.1 AIO01174.1 - 1.3 8.6 6.9 0.038 13.5 0.4 1.7 2 0 0 2 2 2 0 Myc target protein 1 RFXA_RFXANK_bdg PF15289.1 AIO01175.1 - 0.033 14.3 0.2 0.12 12.6 0.1 2.0 1 0 0 1 1 1 0 Regulatory factor X-associated C-terminal binding domain RNase_T PF00929.19 AIO01178.1 - 4.4e-19 69.3 0.1 2.6e-12 47.3 0.0 2.9 2 1 0 2 2 2 2 Exonuclease RRM_1 PF00076.17 AIO01180.1 - 5.7e-20 70.7 0.0 1.1e-06 28.1 0.0 3.8 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 AIO01180.1 - 3.1e-18 65.5 0.0 9.5e-09 35.1 0.0 3.1 2 1 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 AIO01180.1 - 1.2e-06 28.2 0.0 1.2e-05 25.0 0.0 2.5 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RPN7 PF10602.4 AIO01181.1 - 1.6e-47 161.2 0.7 2.3e-47 160.6 0.1 1.6 2 0 0 2 2 2 1 26S proteasome subunit RPN7 PCI PF01399.22 AIO01181.1 - 2.4e-16 59.9 0.1 8.3e-16 58.2 0.0 2.0 3 0 0 3 3 3 1 PCI domain Prefoldin PF02996.12 AIO01183.1 - 2.9e-11 43.0 0.7 5.8e-11 42.0 0.0 1.8 2 0 0 2 2 2 1 Prefoldin subunit Prefoldin_3 PF13758.1 AIO01183.1 - 1.8e-05 24.4 2.7 0.00058 19.5 0.1 2.3 2 0 0 2 2 2 2 Prefoldin subunit Chibby PF14645.1 AIO01183.1 - 0.05 13.4 0.1 0.099 12.5 0.0 1.5 1 0 0 1 1 1 0 Chibby family TPR_11 PF13414.1 AIO01184.1 - 3.4e-20 71.4 21.2 6e-12 45.0 0.9 4.7 4 0 0 4 4 4 3 TPR repeat TPR_2 PF07719.12 AIO01184.1 - 4.4e-10 38.6 24.0 0.0074 16.1 0.3 6.5 6 0 0 6 6 6 5 Tetratricopeptide repeat CS PF04969.11 AIO01184.1 - 1.4e-08 35.1 0.1 4e-08 33.7 0.0 1.8 2 0 0 2 2 2 1 CS domain TPR_16 PF13432.1 AIO01184.1 - 2.4e-08 34.4 2.4 2.4e-08 34.4 1.7 5.0 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_1 PF00515.23 AIO01184.1 - 8e-08 31.5 21.8 0.064 12.8 0.3 6.4 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_19 PF14559.1 AIO01184.1 - 3.7e-07 30.3 16.3 6.5e-06 26.4 0.6 4.7 4 0 0 4 4 4 2 Tetratricopeptide repeat Apc3 PF12895.2 AIO01184.1 - 0.00016 21.7 10.3 0.27 11.3 0.2 3.9 3 0 0 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.1 AIO01184.1 - 0.00017 21.8 30.5 0.019 15.5 0.0 7.5 5 2 2 7 7 7 3 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 AIO01184.1 - 0.0013 18.5 7.6 0.36 10.7 0.1 4.2 4 0 0 4 4 4 1 Fis1 C-terminal tetratricopeptide repeat TPR_12 PF13424.1 AIO01184.1 - 0.021 14.7 28.1 0.1 12.5 0.7 6.2 4 2 2 6 6 6 0 Tetratricopeptide repeat TPR_7 PF13176.1 AIO01184.1 - 0.26 11.1 19.3 1.7 8.6 0.1 6.6 6 0 0 6 6 6 0 Tetratricopeptide repeat FYVE PF01363.16 AIO01185.1 - 0.0033 17.3 10.8 0.0073 16.1 7.5 1.6 1 0 0 1 1 1 1 FYVE zinc finger IBR PF01485.16 AIO01185.1 - 0.23 11.3 6.0 0.56 10.1 4.2 1.6 1 0 0 1 1 1 0 IBR domain CTP_transf_1 PF01148.15 AIO01186.1 - 7.6e-29 101.1 17.9 2.1e-28 99.6 0.2 3.3 2 1 0 2 2 2 1 Cytidylyltransferase family DUF778 PF05608.7 AIO01187.1 - 2.6e-49 166.6 0.0 5.5e-49 165.5 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF778) SNAP PF14938.1 AIO01189.1 - 8.3e-53 179.3 16.6 9.6e-53 179.1 11.5 1.0 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP TPR_12 PF13424.1 AIO01189.1 - 1.4e-07 31.3 5.2 0.0021 17.9 0.7 3.0 1 1 0 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.1 AIO01189.1 - 2.2e-06 27.7 6.9 5.3 7.9 0.0 5.3 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_19 PF14559.1 AIO01189.1 - 0.00013 22.2 5.6 0.17 12.2 0.7 2.8 2 1 0 2 2 2 2 Tetratricopeptide repeat Foie-gras_1 PF11817.3 AIO01189.1 - 0.0011 18.5 3.5 0.0081 15.6 1.9 2.1 1 1 1 2 2 2 2 Foie gras liver health family 1 TPR_7 PF13176.1 AIO01189.1 - 0.015 15.0 6.7 15 5.6 0.1 5.3 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.1 AIO01189.1 - 0.016 15.6 11.5 0.3 11.6 0.2 5.1 5 0 0 5 5 5 0 Tetratricopeptide repeat Apc3 PF12895.2 AIO01189.1 - 0.019 15.1 2.2 0.019 15.1 1.5 2.3 1 1 2 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 DUF410 PF04190.8 AIO01189.1 - 0.027 14.0 1.4 0.055 12.9 0.7 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF410) TPR_11 PF13414.1 AIO01189.1 - 0.029 13.9 11.7 0.34 10.5 0.3 4.1 2 1 3 5 5 5 0 TPR repeat DUF1024 PF06260.7 AIO01189.1 - 0.055 13.6 3.7 2.8 8.1 0.1 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF1024) Alkyl_sulf_dimr PF14863.1 AIO01189.1 - 0.064 13.4 5.7 2.2 8.5 0.4 2.9 1 1 2 3 3 3 0 Alkyl sulfatase dimerisation PPR_3 PF13812.1 AIO01189.1 - 0.12 12.7 0.4 10 6.6 0.0 3.3 3 0 0 3 3 3 0 Pentatricopeptide repeat domain TPR_8 PF13181.1 AIO01189.1 - 0.21 11.4 1.7 15 5.6 0.0 3.7 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.1 AIO01189.1 - 0.23 12.1 11.4 3.1 8.5 0.1 3.9 3 1 0 4 4 4 0 Tetratricopeptide repeat TPR_2 PF07719.12 AIO01189.1 - 0.97 9.5 15.6 41 4.4 0.0 5.7 5 1 1 6 6 6 0 Tetratricopeptide repeat UCH PF00443.24 AIO01191.1 - 2.5e-50 171.0 0.0 3.9e-50 170.4 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 AIO01191.1 - 9.4e-20 71.2 0.1 6.2e-12 45.5 0.0 2.2 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase FG-GAP PF01839.18 AIO01192.1 - 0.00035 20.1 0.1 0.00094 18.8 0.1 1.7 1 0 0 1 1 1 1 FG-GAP repeat VCBS PF13517.1 AIO01192.1 - 0.012 15.9 0.1 0.05 13.9 0.0 2.1 1 0 0 1 1 1 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella TcdB_toxin_midN PF12256.3 AIO01192.1 - 0.076 12.4 0.1 0.29 10.5 0.0 2.0 3 0 0 3 3 3 0 Insecticide toxin TcdB middle/N-terminal region PQQ PF01011.16 AIO01192.1 - 0.11 12.0 1.1 0.89 9.2 0.0 2.9 3 0 0 3 3 3 0 PQQ enzyme repeat BBS2_C PF14782.1 AIO01192.1 - 0.18 10.3 0.0 0.27 9.7 0.0 1.2 1 0 0 1 1 1 0 Ciliary BBSome complex subunit 2, C-terminal TTL PF03133.10 AIO01193.1 - 2e-60 204.2 0.0 1.2e-44 152.3 0.0 2.2 2 0 0 2 2 2 2 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.1 AIO01193.1 - 0.00012 21.0 0.0 0.015 14.0 0.0 2.3 2 0 0 2 2 2 2 YheC/D like ATP-grasp DUF1738 PF08401.6 AIO01194.1 - 6.7e-05 22.6 0.0 2.2 7.9 0.0 3.3 3 0 0 3 3 3 3 Domain of unknown function (DUF1738) NDK PF00334.14 AIO01195.1 - 1.6e-57 193.1 0.0 2.2e-57 192.6 0.0 1.2 1 0 0 1 1 1 1 Nucleoside diphosphate kinase NDK PF00334.14 AIO01196.1 - 9.9e-58 193.7 0.0 1.1e-57 193.5 0.0 1.0 1 0 0 1 1 1 1 Nucleoside diphosphate kinase MCM PF00493.18 AIO01197.1 - 3.9e-127 423.6 0.0 5.2e-127 423.2 0.0 1.1 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 AIO01197.1 - 8.5e-13 48.8 0.0 2e-12 47.6 0.0 1.6 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.16 AIO01197.1 - 1.1e-06 27.9 0.0 0.00015 21.0 0.0 2.4 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 AIO01197.1 - 4.9e-06 26.3 0.0 1.8e-05 24.4 0.0 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 AIO01197.1 - 0.018 14.6 0.0 0.054 13.0 0.0 1.8 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA PF00004.24 AIO01197.1 - 0.069 13.3 0.1 0.38 10.9 0.0 2.3 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 AIO01197.1 - 0.078 12.4 0.0 0.53 9.7 0.0 2.1 1 1 0 1 1 1 0 Sigma-54 interaction domain TBCA PF02970.11 AIO01198.1 - 1.8e-22 79.1 2.9 2.2e-22 78.8 2.0 1.1 1 0 0 1 1 1 1 Tubulin binding cofactor A DREV PF05219.7 AIO01198.1 - 0.0078 15.1 0.1 0.0097 14.8 0.1 1.0 1 0 0 1 1 1 1 DREV methyltransferase TMF_TATA_bd PF12325.3 AIO01198.1 - 0.018 14.7 3.7 0.033 13.9 2.3 1.6 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding Pox_A_type_inc PF04508.7 AIO01198.1 - 0.028 14.1 5.8 11 6.1 0.0 3.5 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat Mnd1 PF03962.10 AIO01198.1 - 0.035 13.7 1.2 0.047 13.3 0.9 1.3 1 0 0 1 1 1 0 Mnd1 family CHASE3 PF05227.8 AIO01198.1 - 0.038 13.6 2.7 0.049 13.3 1.7 1.3 1 1 0 1 1 1 0 CHASE3 domain DUF342 PF03961.8 AIO01198.1 - 0.063 11.6 0.8 0.072 11.5 0.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF342) AAA_30 PF13604.1 AIO01198.1 - 0.065 12.8 0.5 0.092 12.3 0.2 1.4 1 1 0 1 1 1 0 AAA domain Herpes_U30 PF04523.8 AIO01198.1 - 0.07 10.5 0.2 0.072 10.5 0.2 1.1 1 0 0 1 1 1 0 Herpes virus tegument protein U30 TSC22 PF01166.13 AIO01198.1 - 0.077 12.9 1.9 0.13 12.2 0.7 1.8 2 0 0 2 2 2 0 TSC-22/dip/bun family Uds1 PF15456.1 AIO01198.1 - 0.097 12.6 1.9 0.12 12.3 1.3 1.2 1 0 0 1 1 1 0 Up-regulated During Septation DUF4600 PF15372.1 AIO01198.1 - 0.13 12.5 4.0 0.19 11.9 0.5 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4600) DUF904 PF06005.7 AIO01198.1 - 0.33 11.2 3.5 0.54 10.5 1.7 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF904) Phosducin PF02114.11 AIO01199.1 - 6.9e-11 41.3 0.1 7.8e-11 41.1 0.1 1.0 1 0 0 1 1 1 1 Phosducin Thioredoxin PF00085.15 AIO01199.1 - 3.1e-07 30.0 0.0 4.6e-07 29.4 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_3 PF13192.1 AIO01199.1 - 0.014 15.2 0.0 0.033 13.9 0.0 1.6 1 0 0 1 1 1 0 Thioredoxin domain Adeno_100 PF02438.11 AIO01199.1 - 0.089 10.9 0.1 0.12 10.5 0.0 1.1 1 0 0 1 1 1 0 Late 100kD protein DUF2305 PF10230.4 AIO01199.1 - 0.1 11.9 0.6 0.21 10.9 0.3 1.6 2 0 0 2 2 2 0 Uncharacterised conserved protein (DUF2305) Rab5ip PF07019.7 AIO01202.1 - 2.7e-20 72.2 6.6 3.2e-20 72.0 4.6 1.1 1 0 0 1 1 1 1 Rab5-interacting protein (Rab5ip) PTR2 PF00854.16 AIO01202.1 - 0.0069 15.2 3.6 0.0079 15.0 2.5 1.0 1 0 0 1 1 1 1 POT family FA_desaturase PF00487.19 AIO01202.1 - 0.9 8.9 3.6 1.3 8.4 2.5 1.3 1 1 0 1 1 1 0 Fatty acid desaturase DUF21 PF01595.15 AIO01203.1 - 4.8e-30 104.2 10.3 7.4e-30 103.5 7.1 1.2 1 0 0 1 1 1 1 Domain of unknown function DUF21 L_HGMIC_fpl PF10242.4 AIO01203.1 - 1.4 8.8 5.9 0.33 10.9 0.3 2.2 2 0 0 2 2 2 0 Lipoma HMGIC fusion partner-like protein LRR_4 PF12799.2 AIO01204.1 - 8.6e-20 69.9 6.5 5.2e-07 29.1 0.1 4.0 1 1 4 5 5 5 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 AIO01204.1 - 1.3e-09 37.6 3.8 0.0002 21.0 0.2 3.5 2 1 1 3 3 3 3 Leucine rich repeat LRR_1 PF00560.28 AIO01204.1 - 8.9e-07 28.1 6.1 6.8 7.1 0.1 6.6 6 0 0 6 6 6 1 Leucine Rich Repeat LRR_6 PF13516.1 AIO01204.1 - 2.5e-06 26.9 8.4 4.8 7.5 0.2 5.8 3 1 2 5 5 5 4 Leucine Rich repeat LRR_9 PF14580.1 AIO01204.1 - 3.6e-06 26.6 0.0 3.3e-05 23.5 0.0 2.2 1 1 1 2 2 2 2 Leucine-rich repeat LRR_7 PF13504.1 AIO01204.1 - 0.00024 20.8 3.4 6.9 7.3 0.0 5.8 6 0 0 6 6 6 1 Leucine rich repeat MMR_HSR1 PF01926.18 AIO01205.1 - 1.4e-12 47.5 0.0 8.8e-12 45.0 0.0 2.1 2 0 0 2 2 2 1 50S ribosome-binding GTPase DUF258 PF03193.11 AIO01205.1 - 3.5e-05 23.0 0.0 8.9e-05 21.7 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function, DUF258 GTP_EFTU PF00009.22 AIO01205.1 - 0.0023 17.4 0.0 0.17 11.2 0.0 2.6 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain AAA_16 PF13191.1 AIO01205.1 - 0.0087 16.0 0.1 0.026 14.5 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain Dynamin_N PF00350.18 AIO01205.1 - 0.041 13.7 0.1 0.52 10.1 0.0 2.3 1 1 1 2 2 2 0 Dynamin family ABC_tran PF00005.22 AIO01205.1 - 0.045 14.0 0.0 0.13 12.6 0.0 1.7 1 0 0 1 1 1 0 ABC transporter Miro PF08477.8 AIO01205.1 - 0.055 13.9 0.0 0.15 12.5 0.0 1.8 1 0 0 1 1 1 0 Miro-like protein DnaJ PF00226.26 AIO01206.1 - 2.2e-21 75.3 0.0 4.8e-21 74.2 0.0 1.6 1 0 0 1 1 1 1 DnaJ domain Angiomotin_C PF12240.3 AIO01206.1 - 3 7.2 10.7 0.49 9.8 3.8 2.3 2 1 0 2 2 2 0 Angiomotin C terminal Metallophos PF00149.23 AIO01207.1 - 8.2e-43 146.1 0.1 1e-42 145.8 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Ras PF00071.17 AIO01208.1 - 5.9e-12 45.2 0.1 1.3e-11 44.1 0.0 1.5 1 1 0 1 1 1 1 Ras family Miro PF08477.8 AIO01208.1 - 3.3e-06 27.5 0.0 7.5e-06 26.4 0.0 1.7 1 1 0 1 1 1 1 Miro-like protein Gtr1_RagA PF04670.7 AIO01208.1 - 0.00015 21.0 0.0 0.00024 20.3 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region IBR PF01485.16 AIO01208.1 - 0.00031 20.5 0.1 0.00077 19.2 0.1 1.6 1 0 0 1 1 1 1 IBR domain YdjO PF14169.1 AIO01208.1 - 0.014 14.8 0.3 0.029 13.7 0.2 1.5 1 0 0 1 1 1 0 Cold-inducible protein YdjO Zn_Tnp_IS1 PF03811.8 AIO01208.1 - 0.057 12.9 0.9 0.16 11.5 0.1 2.3 2 0 0 2 2 2 0 InsA N-terminal domain zf-MIZ PF02891.15 AIO01211.1 - 5e-10 38.7 6.9 1e-09 37.7 4.8 1.5 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger zf-Nse PF11789.3 AIO01211.1 - 2.7e-06 26.8 1.7 5.3e-06 25.8 1.2 1.5 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit RRN7 PF11781.3 AIO01211.1 - 0.0072 15.8 3.7 0.18 11.3 0.4 2.7 2 0 0 2 2 2 2 RNA polymerase I-specific transcription initiation factor Rrn7 DZR PF12773.2 AIO01211.1 - 0.058 13.2 0.2 0.058 13.2 0.1 2.3 2 0 0 2 2 2 0 Double zinc ribbon zf-NADH-PPase PF09297.6 AIO01211.1 - 0.85 9.1 8.2 0.086 12.3 2.1 2.1 2 0 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain ABC_tran PF00005.22 AIO01212.1 - 5.1e-35 120.7 0.0 1.8e-34 119.0 0.0 1.9 3 0 0 3 3 2 1 ABC transporter ABC_membrane PF00664.18 AIO01212.1 - 1.2e-21 77.3 6.2 1.7e-21 76.8 4.3 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region SMC_N PF02463.14 AIO01212.1 - 3.3e-06 26.4 0.8 0.00044 19.5 0.6 2.4 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 AIO01212.1 - 4.5e-06 26.8 0.0 0.0023 17.9 0.0 2.3 1 1 0 2 2 2 2 AAA domain AAA_29 PF13555.1 AIO01212.1 - 0.00055 19.3 0.7 0.0022 17.5 0.1 2.2 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_16 PF13191.1 AIO01212.1 - 0.0026 17.7 0.0 0.0054 16.7 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain Pox_A31 PF05771.6 AIO01212.1 - 0.0032 17.2 0.1 0.0076 16.0 0.0 1.6 1 0 0 1 1 1 1 Poxvirus A31 protein AAA_22 PF13401.1 AIO01212.1 - 0.0061 16.6 0.1 0.072 13.2 0.1 2.4 1 1 0 1 1 1 1 AAA domain DUF258 PF03193.11 AIO01212.1 - 0.012 14.8 0.0 0.021 13.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_17 PF13207.1 AIO01212.1 - 0.016 16.0 0.0 0.04 14.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.1 AIO01212.1 - 0.022 14.6 0.0 0.06 13.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain MobB PF03205.9 AIO01212.1 - 0.029 14.0 0.0 0.066 12.9 0.0 1.7 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_23 PF13476.1 AIO01212.1 - 0.035 14.4 0.2 0.17 12.1 0.2 1.9 1 1 1 2 2 2 0 AAA domain AAA PF00004.24 AIO01212.1 - 0.051 13.7 0.1 9 6.5 0.0 2.6 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.1 AIO01212.1 - 0.064 13.5 0.0 0.29 11.4 0.0 2.2 3 0 0 3 3 2 0 AAA domain MMR_HSR1 PF01926.18 AIO01212.1 - 0.12 12.3 0.0 0.29 11.0 0.0 1.9 1 1 0 1 1 1 0 50S ribosome-binding GTPase FSH1 PF03959.8 AIO01214.1 - 2.7e-28 98.8 0.0 3.9e-28 98.3 0.0 1.2 1 0 0 1 1 1 1 Serine hydrolase (FSH1) MMR_HSR1_C PF08438.5 AIO01214.1 - 5.8e-25 87.6 0.0 1.6e-24 86.2 0.0 1.8 2 0 0 2 2 2 1 GTPase of unknown function C-terminal MMR_HSR1 PF01926.18 AIO01214.1 - 4.2e-14 52.5 0.0 9.5e-14 51.3 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase RWD PF05773.17 AIO01214.1 - 1e-05 25.3 0.0 2.2e-05 24.3 0.0 1.5 1 0 0 1 1 1 1 RWD domain Abhydrolase_5 PF12695.2 AIO01214.1 - 0.00039 20.1 0.0 0.0014 18.3 0.0 2.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family FeoB_N PF02421.13 AIO01214.1 - 0.0014 17.9 0.0 0.0059 15.8 0.0 2.0 2 0 0 2 2 2 1 Ferrous iron transport protein B Ribosomal_L3 PF00297.17 AIO01215.1 - 8.2e-100 333.5 10.0 1e-99 333.2 6.9 1.1 1 0 0 1 1 1 1 Ribosomal protein L3 Aldedh PF00171.17 AIO01216.1 - 1e-18 66.9 2.8 1.1e-13 50.3 0.5 2.3 2 0 0 2 2 2 2 Aldehyde dehydrogenase family YadA_anchor PF03895.10 AIO01216.1 - 3 7.9 7.4 0.31 11.0 0.2 2.9 3 0 0 3 3 3 0 YadA-like C-terminal region IQ PF00612.22 AIO01217.1 - 1e-15 55.7 105.4 1.6e-05 24.1 2.5 12.9 12 0 0 12 12 12 8 IQ calmodulin-binding motif DUF480 PF04337.7 AIO01217.1 - 8.9e-06 25.6 13.8 0.22 11.3 0.3 4.7 3 0 0 3 3 3 3 Protein of unknown function, DUF480 LRR_4 PF12799.2 AIO01218.1 - 1.2e-09 37.5 1.7 7.8e-06 25.3 0.3 3.1 2 1 1 3 3 3 2 Leucine Rich repeats (2 copies) LRR_6 PF13516.1 AIO01218.1 - 2.5e-07 30.0 1.7 0.019 14.9 0.1 4.0 4 0 0 4 4 4 2 Leucine Rich repeat LRR_1 PF00560.28 AIO01218.1 - 0.0002 20.9 0.4 1.4 9.2 0.0 4.4 4 0 0 4 4 4 1 Leucine Rich Repeat LRR_7 PF13504.1 AIO01218.1 - 0.019 15.1 0.3 11 6.7 0.0 4.0 3 0 0 3 3 3 0 Leucine rich repeat LRR_8 PF13855.1 AIO01218.1 - 0.074 12.8 0.6 0.21 11.3 0.3 1.9 2 0 0 2 2 2 0 Leucine rich repeat L51_S25_CI-B8 PF05047.11 AIO01219.1 - 0.0062 16.2 0.1 0.01 15.5 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain DUF2738 PF10927.3 AIO01219.1 - 0.042 12.8 0.0 0.062 12.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2738) COG5 PF10392.4 AIO01221.1 - 1.8e-14 53.8 18.4 1.9e-12 47.2 1.4 4.3 3 1 1 4 4 4 2 Golgi transport complex subunit 5 DUF1664 PF07889.7 AIO01221.1 - 0.01 15.6 0.2 0.028 14.2 0.2 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) DUF2360 PF10152.4 AIO01221.1 - 0.072 13.3 2.1 12 6.2 0.0 3.0 2 1 0 2 2 2 0 Predicted coiled-coil domain-containing protein (DUF2360) COG2 PF06148.6 AIO01221.1 - 0.9 9.4 6.4 0.85 9.4 1.9 3.0 3 1 0 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 Miro PF08477.8 AIO01223.1 - 1.3e-05 25.6 0.0 2.4e-05 24.8 0.0 1.5 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 AIO01223.1 - 2e-05 23.9 0.4 0.0015 17.7 0.2 2.3 1 1 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 AIO01223.1 - 3.7e-05 23.6 0.0 5.4e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Ras PF00071.17 AIO01223.1 - 0.00036 19.9 0.0 0.0013 18.1 0.0 1.9 2 1 0 2 2 2 1 Ras family G-alpha PF00503.15 AIO01223.1 - 0.0035 16.0 0.3 0.9 8.1 0.0 2.2 1 1 1 2 2 2 2 G-protein alpha subunit Dynamin_N PF00350.18 AIO01223.1 - 0.013 15.2 0.1 0.05 13.4 0.0 1.8 1 1 1 2 2 2 0 Dynamin family GTP_EFTU PF00009.22 AIO01223.1 - 0.015 14.7 0.0 0.023 14.1 0.0 1.3 1 0 0 1 1 1 0 Elongation factor Tu GTP binding domain PduV-EutP PF10662.4 AIO01223.1 - 0.018 14.5 0.0 0.036 13.5 0.0 1.5 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_17 PF13207.1 AIO01223.1 - 0.022 15.5 0.1 0.035 14.9 0.0 1.8 1 1 0 1 1 1 0 AAA domain SRPRB PF09439.5 AIO01223.1 - 0.055 12.6 0.1 0.11 11.7 0.1 1.7 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_18 PF13238.1 AIO01223.1 - 0.13 12.5 0.0 0.26 11.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain Gtr1_RagA PF04670.7 AIO01223.1 - 0.15 11.1 0.1 1.5 7.8 0.0 2.3 2 1 0 2 2 2 0 Gtr1/RagA G protein conserved region AAA_16 PF13191.1 AIO01225.1 - 3.5e-06 27.1 0.1 6.8e-06 26.1 0.0 1.5 1 1 0 1 1 1 1 AAA ATPase domain GTP_EFTU PF00009.22 AIO01225.1 - 2.6e-05 23.7 0.0 0.12 11.8 0.0 2.5 3 0 0 3 3 2 2 Elongation factor Tu GTP binding domain Miro PF08477.8 AIO01225.1 - 5.4e-05 23.6 0.0 0.001 19.5 0.0 2.3 2 0 0 2 2 2 1 Miro-like protein G-alpha PF00503.15 AIO01225.1 - 6.2e-05 21.8 0.0 0.0016 17.2 0.0 2.2 2 0 0 2 2 2 1 G-protein alpha subunit AAA_22 PF13401.1 AIO01225.1 - 0.00024 21.2 0.1 0.033 14.3 0.0 2.7 2 1 0 2 2 2 1 AAA domain AAA_19 PF13245.1 AIO01225.1 - 0.00027 20.6 0.0 0.00073 19.2 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain NACHT PF05729.7 AIO01225.1 - 0.00048 19.8 0.0 0.002 17.7 0.0 1.9 2 0 0 2 2 2 1 NACHT domain cobW PF02492.14 AIO01225.1 - 0.00062 19.2 0.1 0.0053 16.2 0.0 2.1 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain FtsK_SpoIIIE PF01580.13 AIO01225.1 - 0.0011 18.4 0.0 0.0022 17.4 0.0 1.5 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA_33 PF13671.1 AIO01225.1 - 0.002 18.0 0.4 0.0068 16.2 0.3 2.0 1 1 0 1 1 1 1 AAA domain ATP_bind_1 PF03029.12 AIO01225.1 - 0.002 17.6 0.4 0.09 12.3 0.2 2.2 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein AAA_24 PF13479.1 AIO01225.1 - 0.0042 16.6 0.1 0.11 12.0 0.0 2.3 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.7 AIO01225.1 - 0.0053 15.8 0.0 0.012 14.7 0.0 1.6 1 0 0 1 1 1 1 Zeta toxin Viral_helicase1 PF01443.13 AIO01225.1 - 0.013 15.0 0.0 0.022 14.2 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase ABC_tran PF00005.22 AIO01225.1 - 0.015 15.6 0.0 0.027 14.7 0.0 1.6 1 1 0 1 1 1 0 ABC transporter Arf PF00025.16 AIO01225.1 - 0.015 14.5 0.0 0.2 10.9 0.0 2.1 2 0 0 2 2 2 0 ADP-ribosylation factor family T2SE PF00437.15 AIO01225.1 - 0.019 13.9 0.0 0.04 12.7 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein NTPase_1 PF03266.10 AIO01225.1 - 0.023 14.3 0.1 0.055 13.1 0.1 1.6 1 0 0 1 1 1 0 NTPase NB-ARC PF00931.17 AIO01225.1 - 0.026 13.3 0.0 0.047 12.5 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain AAA_28 PF13521.1 AIO01225.1 - 0.032 14.2 0.0 0.071 13.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain Pox_A32 PF04665.7 AIO01225.1 - 0.034 13.4 0.0 0.099 11.9 0.0 1.7 2 0 0 2 2 2 0 Poxvirus A32 protein AAA PF00004.24 AIO01225.1 - 0.042 14.0 0.0 0.091 12.9 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DAP3 PF10236.4 AIO01225.1 - 0.047 12.6 0.0 0.086 11.7 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 AAA_17 PF13207.1 AIO01225.1 - 0.048 14.4 0.1 0.13 13.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.1 AIO01225.1 - 0.051 13.1 0.0 0.11 12.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.1 AIO01225.1 - 0.052 13.0 0.0 0.12 11.9 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_10 PF12846.2 AIO01225.1 - 0.06 12.7 0.1 0.11 11.9 0.1 1.3 1 0 0 1 1 1 0 AAA-like domain MCM PF00493.18 AIO01225.1 - 0.061 12.1 0.0 0.095 11.4 0.0 1.2 1 0 0 1 1 1 0 MCM2/3/5 family DUF258 PF03193.11 AIO01225.1 - 0.067 12.3 0.0 0.13 11.4 0.0 1.5 1 1 0 1 1 1 0 Protein of unknown function, DUF258 MMR_HSR1 PF01926.18 AIO01225.1 - 0.086 12.8 0.0 0.17 11.8 0.0 1.7 1 1 0 1 1 1 0 50S ribosome-binding GTPase Septin PF00735.13 AIO01225.1 - 0.092 11.7 0.0 0.14 11.1 0.0 1.3 1 0 0 1 1 1 0 Septin Mg_chelatase PF01078.16 AIO01225.1 - 0.093 11.8 0.0 0.16 11.1 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_18 PF13238.1 AIO01225.1 - 0.096 12.9 0.0 0.21 11.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.1 AIO01225.1 - 0.1 12.4 0.0 0.18 11.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain SRPRB PF09439.5 AIO01225.1 - 0.11 11.7 0.0 0.19 10.9 0.0 1.4 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit UvrD-helicase PF00580.16 AIO01225.1 - 0.13 11.5 0.1 0.22 10.7 0.0 1.3 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain Ras PF00071.17 AIO01225.1 - 0.13 11.5 0.0 1.6 8.1 0.0 2.2 2 0 0 2 2 2 0 Ras family Arch_ATPase PF01637.13 AIO01225.1 - 0.15 11.7 0.0 0.33 10.6 0.0 1.8 1 1 0 1 1 1 0 Archaeal ATPase Pkinase PF00069.20 AIO01227.1 - 4.6e-74 248.8 0.0 6.6e-74 248.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AIO01227.1 - 7.6e-36 123.5 0.0 4e-35 121.1 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 AIO01227.1 - 0.0083 15.1 0.0 0.019 13.9 0.0 1.5 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 AIO01227.1 - 0.019 14.7 0.6 0.22 11.2 0.0 2.5 1 1 1 2 2 2 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 AIO01227.1 - 0.053 12.3 0.0 0.086 11.6 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Glucosamine_iso PF01182.15 AIO01228.1 - 8.8e-23 81.0 0.0 1.2e-22 80.5 0.0 1.2 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase Cpn60_TCP1 PF00118.19 AIO01229.1 - 2.1e-133 445.4 6.9 2.4e-133 445.2 4.8 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family DUF4090 PF13319.1 AIO01229.1 - 0.062 13.2 0.0 0.2 11.6 0.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF4090) CTDII PF01556.13 AIO01232.1 - 2.9e-20 71.9 0.0 9.3e-20 70.3 0.0 1.9 2 0 0 2 2 2 1 DnaJ C terminal domain DnaJ PF00226.26 AIO01232.1 - 2.7e-17 62.2 4.0 5.3e-17 61.3 2.7 1.5 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.14 AIO01232.1 - 2.2e-13 50.0 14.0 3.6e-13 49.3 9.7 1.4 1 0 0 1 1 1 1 DnaJ central domain Arabinose_Isome PF02610.10 AIO01232.1 - 0.00059 18.8 0.0 0.00083 18.4 0.0 1.1 1 0 0 1 1 1 1 L-arabinose isomerase PRAP PF15314.1 AIO01232.1 - 0.0032 17.7 0.2 0.42 10.9 0.1 2.9 3 0 0 3 3 3 1 Proline-rich acidic protein 1, pregnancy-specific uterine HypA PF01155.14 AIO01232.1 - 0.03 14.0 5.5 1.9 8.2 0.3 2.4 2 0 0 2 2 2 0 Hydrogenase expression/synthesis hypA family DZR PF12773.2 AIO01232.1 - 0.19 11.5 12.9 1.3 8.9 2.1 2.3 1 1 1 2 2 2 0 Double zinc ribbon A2L_zn_ribbon PF08792.5 AIO01232.1 - 2.9 7.4 7.7 25 4.4 0.0 4.0 4 0 0 4 4 4 0 A2L zinc ribbon domain Pyr_redox_2 PF07992.9 AIO01233.1 - 5.1e-41 140.7 2.0 5.1e-41 140.7 1.4 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.17 AIO01233.1 - 7.5e-41 138.6 0.8 1.8e-40 137.3 0.6 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.22 AIO01233.1 - 5.8e-19 68.2 12.0 2e-17 63.3 1.5 3.2 3 1 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 AIO01233.1 - 1.8e-10 40.2 10.7 3.7e-09 35.9 3.2 2.7 2 1 0 2 2 2 2 Glucose inhibited division protein A FAD_oxidored PF12831.2 AIO01233.1 - 2.3e-10 40.1 0.9 2.3e-10 40.1 0.6 3.1 3 1 1 4 4 4 2 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 AIO01233.1 - 6.1e-09 36.2 0.4 8.3e-06 26.0 0.1 2.5 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 AIO01233.1 - 4.6e-07 29.7 6.6 0.00011 22.1 0.6 2.5 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 AIO01233.1 - 6.2e-07 28.6 1.1 6.2e-07 28.6 0.8 2.9 2 1 0 3 3 3 1 FAD binding domain Thi4 PF01946.12 AIO01233.1 - 1.6e-06 27.4 1.5 8.7e-05 21.7 0.1 2.6 2 0 0 2 2 2 1 Thi4 family FAD_binding_3 PF01494.14 AIO01233.1 - 7.9e-05 21.8 12.9 0.031 13.3 0.4 3.2 2 1 1 3 3 3 3 FAD binding domain K_oxygenase PF13434.1 AIO01233.1 - 8.6e-05 21.6 0.6 0.038 12.9 0.0 2.5 2 1 1 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.19 AIO01233.1 - 8.8e-05 21.5 19.4 0.055 12.3 1.5 4.1 2 2 1 4 4 4 3 FAD dependent oxidoreductase 3HCDH_N PF02737.13 AIO01233.1 - 0.00031 20.4 6.2 0.0011 18.5 0.5 3.4 2 1 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain HI0933_like PF03486.9 AIO01233.1 - 0.00034 19.2 1.3 0.00034 19.2 0.9 3.8 3 1 1 4 4 4 1 HI0933-like protein AlaDh_PNT_C PF01262.16 AIO01233.1 - 0.0069 15.9 1.7 0.24 10.9 0.1 2.7 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain XdhC_C PF13478.1 AIO01233.1 - 0.023 15.0 0.2 0.42 10.9 0.0 2.4 2 0 0 2 2 2 0 XdhC Rossmann domain Lycopene_cycl PF05834.7 AIO01233.1 - 0.16 10.8 2.4 0.95 8.3 0.0 2.5 2 1 0 2 2 2 0 Lycopene cyclase protein NAD_binding_7 PF13241.1 AIO01233.1 - 8.6 6.6 8.5 3.8 7.8 1.3 3.0 3 1 0 3 3 2 0 Putative NAD(P)-binding Cyclin_N PF00134.18 AIO01234.1 - 2.6e-38 130.4 1.0 2.6e-38 130.4 0.7 2.0 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 AIO01234.1 - 6.2e-34 116.4 0.2 2.7e-33 114.4 0.0 2.0 2 0 0 2 2 2 1 Cyclin, C-terminal domain Na_H_antiporter PF03553.9 AIO01235.1 - 0.11 11.5 0.0 0.12 11.4 0.0 1.0 1 0 0 1 1 1 0 Na+/H+ antiporter family zf-B_box PF00643.19 AIO01237.1 - 5.6e-07 29.3 3.8 1.3e-06 28.1 2.6 1.7 1 0 0 1 1 1 1 B-box zinc finger PTN_MK_C PF01091.13 AIO01237.1 - 0.031 14.2 0.1 0.075 13.0 0.0 1.6 1 0 0 1 1 1 0 PTN/MK heparin-binding protein family, C-terminal domain Lipase_3 PF01764.20 AIO01238.1 - 3.7e-11 42.7 0.0 1e-10 41.3 0.0 1.8 1 1 0 1 1 1 1 Lipase (class 3) Fox-1_C PF12414.3 AIO01238.1 - 0.16 12.3 7.6 2.8 8.3 0.0 4.0 3 0 0 3 3 3 0 Calcitonin gene-related peptide regulator C terminal tRNA-synt_1c PF00749.16 AIO01238.1 - 0.24 10.0 0.1 0.39 9.3 0.0 1.2 1 0 0 1 1 1 0 tRNA synthetases class I (E and Q), catalytic domain Voltage_CLC PF00654.15 AIO01239.1 - 3.2e-75 253.3 24.5 3.2e-75 253.3 16.9 1.5 2 0 0 2 2 2 1 Voltage gated chloride channel CBS PF00571.23 AIO01239.1 - 2e-10 40.2 0.6 3.1e-05 23.6 0.2 2.5 2 0 0 2 2 2 2 CBS domain Romo1 PF10247.4 AIO01239.1 - 0.84 9.8 5.6 0.2 11.8 0.2 2.8 3 0 0 3 3 3 0 Reactive mitochondrial oxygen species modulator 1 TruD PF01142.13 AIO01240.1 - 2.1e-34 118.8 0.2 2.2e-14 52.9 0.0 4.1 4 0 0 4 4 4 4 tRNA pseudouridine synthase D (TruD) zf-MYND PF01753.13 AIO01241.1 - 0.0022 17.8 13.4 0.0022 17.8 9.3 2.5 2 0 0 2 2 2 1 MYND finger zf-Mss51 PF13824.1 AIO01241.1 - 0.018 14.8 8.1 0.018 14.8 5.6 2.1 2 0 0 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 zf-HIT PF04438.11 AIO01241.1 - 6 6.6 14.5 0.62 9.7 4.7 2.8 3 0 0 3 3 3 0 HIT zinc finger Abhydrolase_6 PF12697.2 AIO01242.1 - 3e-05 24.0 9.6 0.00012 22.0 2.7 2.8 1 1 0 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 AIO01242.1 - 0.00011 21.9 0.7 0.23 11.2 0.1 3.2 3 0 0 3 3 3 2 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 AIO01242.1 - 0.36 10.3 9.8 1.3 8.4 5.0 2.4 2 1 0 2 2 2 0 alpha/beta hydrolase fold UPF0564 PF10595.4 AIO01243.1 - 4.1e-06 25.9 0.5 4.1e-06 25.9 0.4 3.4 4 1 0 4 4 4 2 Uncharacterised protein family UPF0564 DUF4071 PF13281.1 AIO01243.1 - 0.047 12.5 0.7 0.083 11.7 0.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4071) DUF2135 PF09906.4 AIO01244.1 - 0.081 12.8 0.3 17 5.4 0.0 2.6 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2135) zf-C2HC_2 PF13913.1 AIO01245.1 - 9e-20 69.8 15.4 8e-09 34.9 0.4 3.8 3 0 0 3 3 3 3 zinc-finger of a C2HC-type zf-ribbon_3 PF13248.1 AIO01245.1 - 2.7e-05 23.2 12.6 0.00083 18.4 3.7 3.6 3 0 0 3 3 3 1 zinc-ribbon domain zinc_ribbon_2 PF13240.1 AIO01245.1 - 0.00013 21.3 15.3 0.0045 16.4 4.2 3.8 3 0 0 3 3 3 2 zinc-ribbon domain zf-H2C2_2 PF13465.1 AIO01245.1 - 0.047 14.0 2.8 3.8 7.9 0.1 3.7 3 0 0 3 3 3 0 Zinc-finger double domain zf-CHCC PF10276.4 AIO01245.1 - 0.091 12.6 2.4 0.41 10.5 0.1 2.9 3 0 0 3 3 3 0 Zinc-finger domain NOB1_Zn_bind PF08772.6 AIO01245.1 - 0.37 10.6 3.5 1.4 8.7 2.4 2.0 1 0 0 1 1 1 0 Nin one binding (NOB1) Zn-ribbon like zf-LYAR PF08790.6 AIO01245.1 - 0.45 10.2 2.9 11 5.8 0.7 2.6 2 0 0 2 2 2 0 LYAR-type C2HC zinc finger DZR PF12773.2 AIO01245.1 - 0.85 9.4 17.4 0.72 9.7 7.7 3.4 3 1 1 4 4 4 0 Double zinc ribbon Sgf11 PF08209.6 AIO01245.1 - 6.4 6.1 8.2 9.2 5.6 0.4 2.7 2 0 0 2 2 2 0 Sgf11 (transcriptional regulation protein) RNase_PH PF01138.16 AIO01246.1 - 1.5e-06 28.5 0.0 2.6e-06 27.7 0.0 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.10 AIO01246.1 - 0.00066 19.5 0.0 0.0011 18.8 0.0 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 NUC205 PF08168.6 AIO01246.1 - 0.011 15.1 0.1 0.57 9.6 0.0 2.5 2 0 0 2 2 2 0 NUC205 domain RRM_1 PF00076.17 AIO01247.1 - 2.4e-11 43.0 0.0 5.6e-08 32.3 0.0 2.7 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 AIO01247.1 - 1.4e-09 37.8 0.0 4.8e-07 29.6 0.0 2.8 3 0 0 3 3 3 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 AIO01247.1 - 1.3e-05 24.9 0.0 0.00013 21.6 0.0 2.5 3 0 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Hepatitis_core PF00906.15 AIO01247.1 - 0.0077 15.9 0.1 0.013 15.1 0.1 1.3 1 0 0 1 1 1 1 Hepatitis core antigen DUF515 PF04415.7 AIO01247.1 - 1.5 6.9 3.9 2.5 6.2 2.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF515) HCV_NS5a_1a PF08300.8 AIO01248.1 - 0.054 13.3 0.1 0.13 12.1 0.1 1.5 1 0 0 1 1 1 0 Hepatitis C virus non-structural 5a zinc finger domain TPR_16 PF13432.1 AIO01248.1 - 0.56 10.9 20.0 1.1 10.0 0.0 5.3 6 0 0 6 6 6 0 Tetratricopeptide repeat DEAD PF00270.24 AIO01249.1 - 3.8e-17 62.2 0.0 8.3e-17 61.1 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 AIO01249.1 - 5.2e-06 26.2 0.0 2.7e-05 23.9 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 AIO01249.1 - 0.00015 21.6 0.0 0.00043 20.1 0.0 1.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit IstB_IS21 PF01695.12 AIO01249.1 - 0.011 15.1 0.0 0.093 12.1 0.0 2.3 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_22 PF13401.1 AIO01249.1 - 0.011 15.8 0.0 7.7 6.6 0.0 2.8 2 0 0 2 2 2 0 AAA domain PhoH PF02562.11 AIO01249.1 - 0.017 14.3 0.0 0.029 13.5 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein AAA PF00004.24 AIO01249.1 - 0.036 14.2 0.1 0.59 10.3 0.0 2.4 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Beta-lactamase2 PF13354.1 AIO01249.1 - 0.04 13.3 0.2 0.28 10.6 0.0 2.3 2 0 0 2 2 2 0 Beta-lactamase enzyme family zf-CCCH PF00642.19 AIO01251.1 - 0.00025 20.6 16.9 0.00076 19.0 1.1 2.4 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Robl_LC7 PF03259.12 AIO01253.1 - 4.2e-10 39.0 0.2 4.9e-09 35.6 0.0 1.9 2 0 0 2 2 2 1 Roadblock/LC7 domain Nol1_Nop2_Fmu PF01189.12 AIO01255.1 - 0.00052 19.4 0.0 0.00094 18.6 0.0 1.3 1 0 0 1 1 1 1 NOL1/NOP2/sun family YMF19 PF02326.10 AIO01256.1 - 0.17 12.4 0.5 0.24 11.9 0.3 1.3 1 1 0 1 1 1 0 Plant ATP synthase F0 Band_3_cyto PF07565.8 AIO01257.1 - 0.011 15.3 5.1 0.013 14.9 3.5 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Glu_cyclase_2 PF05096.7 AIO01257.1 - 0.037 13.0 0.0 0.051 12.5 0.0 1.2 1 0 0 1 1 1 0 Glutamine cyclotransferase Baculo_gp64 PF03273.8 AIO01257.1 - 0.13 10.3 2.7 0.57 8.2 0.3 2.1 2 0 0 2 2 2 0 Baculovirus gp64 envelope glycoprotein family Spc24 PF08286.6 AIO01257.1 - 0.34 10.6 7.6 1.2 8.8 1.5 2.6 2 1 1 3 3 3 0 Spc24 subunit of Ndc80 HR1 PF02185.11 AIO01257.1 - 0.57 9.9 9.2 1.7 8.4 1.6 2.8 3 0 0 3 3 3 0 Hr1 repeat DUF2205 PF10224.4 AIO01257.1 - 0.65 9.6 8.4 1.5 8.4 0.2 3.0 3 1 0 3 3 3 0 Predicted coiled-coil protein (DUF2205) BRE1 PF08647.6 AIO01257.1 - 0.81 9.7 7.2 0.25 11.3 2.0 2.2 2 0 0 2 2 2 0 BRE1 E3 ubiquitin ligase MscS_TM PF12794.2 AIO01257.1 - 1.1 7.8 4.7 1.7 7.1 3.2 1.2 1 0 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 Seryl_tRNA_N PF02403.17 AIO01257.1 - 1.2 9.2 9.4 1.4 9.0 0.4 2.8 2 1 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain CDC37_N PF03234.9 AIO01257.1 - 1.9 8.7 9.0 6 7.1 5.0 2.2 1 1 1 2 2 2 0 Cdc37 N terminal kinase binding CENP-H PF05837.7 AIO01257.1 - 2.2 8.4 11.3 0.83 9.8 2.1 2.9 3 0 0 3 3 3 0 Centromere protein H (CENP-H) MitMem_reg PF13012.1 AIO01257.1 - 3.1 7.9 6.1 4.8 7.3 3.0 2.2 2 1 0 2 2 2 0 Maintenance of mitochondrial structure and function ATG16 PF08614.6 AIO01257.1 - 4.2 7.1 16.1 0.13 12.1 4.7 2.4 1 1 2 3 3 3 0 Autophagy protein 16 (ATG16) PH_6 PF15406.1 AIO01259.1 - 0.15 12.1 0.0 0.31 11.0 0.0 1.5 1 0 0 1 1 1 0 Pleckstrin homology domain DUF2786 PF10979.3 AIO01260.1 - 6.2 6.6 11.5 0.19 11.4 3.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2786) ECH_C PF13766.1 AIO01262.1 - 1.4e-22 80.0 0.0 2.1e-22 79.4 0.0 1.3 1 0 0 1 1 1 1 2-enoyl-CoA Hydratase C-terminal region ECH PF00378.15 AIO01262.1 - 4.4e-13 48.9 0.0 6.6e-13 48.3 0.0 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family ECH_C PF13766.1 AIO01263.1 - 6.2e-28 97.3 0.0 9e-28 96.7 0.0 1.2 1 0 0 1 1 1 1 2-enoyl-CoA Hydratase C-terminal region ECH PF00378.15 AIO01263.1 - 4e-22 78.5 0.0 4.7e-22 78.3 0.0 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family BT1 PF03092.11 AIO01266.1 - 1.2e-29 103.3 23.0 2.2e-29 102.4 15.9 1.3 1 1 0 1 1 1 1 BT1 family DUF4257 PF14074.1 AIO01266.1 - 0.14 11.7 2.2 1.1 8.9 0.2 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF4257) TMEM18 PF14770.1 AIO01267.1 - 5.5e-29 100.2 0.4 6.9e-29 99.8 0.3 1.1 1 0 0 1 1 1 1 Transmembrane protein 18 Spexin PF15171.1 AIO01267.1 - 0.077 12.9 0.4 0.14 12.1 0.3 1.4 1 0 0 1 1 1 0 Neuropeptide secretory protein family, NPQ, spexin TYW3 PF02676.9 AIO01269.1 - 5.6e-33 113.8 0.0 6.5e-33 113.5 0.0 1.0 1 0 0 1 1 1 1 Methyltransferase TYW3 MAT_Alpha1 PF04769.7 AIO01272.1 - 0.0066 15.8 4.6 0.011 15.1 3.2 1.4 1 1 0 1 1 1 1 Mating-type protein MAT alpha 1 HMG_box_2 PF09011.5 AIO01272.1 - 0.29 11.5 4.4 0.41 11.0 0.0 2.4 1 1 0 2 2 2 0 HMG-box domain CKS PF01111.14 AIO01273.1 - 7e-39 131.5 0.8 8.5e-39 131.2 0.6 1.1 1 0 0 1 1 1 1 Cyclin-dependent kinase regulatory subunit TPR_11 PF13414.1 AIO01274.1 - 9.4e-08 31.6 2.0 0.00052 19.6 0.1 2.5 1 1 1 2 2 2 2 TPR repeat TPR_2 PF07719.12 AIO01274.1 - 8.5e-07 28.4 0.6 0.097 12.6 0.0 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.23 AIO01274.1 - 2.8e-06 26.6 0.6 0.091 12.4 0.0 3.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.1 AIO01274.1 - 9.4e-05 22.2 2.0 0.095 12.6 0.0 2.3 1 1 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.1 AIO01274.1 - 0.011 15.3 0.0 1.1 9.2 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_9 PF13371.1 AIO01274.1 - 0.04 13.7 5.7 1.2 9.0 0.4 3.8 3 2 1 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.1 AIO01274.1 - 0.39 11.2 4.1 21 5.8 0.1 4.2 4 1 0 4 4 4 0 Tetratricopeptide repeat SHQ1 PF04925.10 AIO01275.1 - 4e-51 173.1 0.0 7.6e-51 172.2 0.0 1.4 1 0 0 1 1 1 1 SHQ1 protein WD40 PF00400.27 AIO01276.1 - 0.026 14.4 3.7 5 7.1 0.0 4.4 4 0 0 4 4 4 0 WD domain, G-beta repeat Pox_P21 PF05313.7 AIO01277.1 - 0.00018 20.8 0.8 0.00018 20.8 0.5 2.6 1 1 1 3 3 3 1 Poxvirus P21 membrane protein Cornichon PF03311.9 AIO01277.1 - 0.0018 18.3 10.0 0.0018 18.3 6.9 1.5 1 1 0 1 1 1 1 Cornichon protein LRRC37AB_C PF14914.1 AIO01277.1 - 0.084 12.3 3.8 0.83 9.0 1.1 2.3 2 0 0 2 2 2 0 LRRC37A/B like protein 1 C-terminal domain Tic20 PF09685.5 AIO01277.1 - 1.2 9.0 18.3 2.7 7.9 3.3 2.1 2 0 0 2 2 2 0 Tic20-like protein Chromate_transp PF02417.10 AIO01277.1 - 5.4 6.5 12.2 0.34 10.4 3.9 2.1 2 1 1 3 3 3 0 Chromate transporter Cornichon PF03311.9 AIO01278.1 - 1.1e-12 48.2 1.3 1.1e-12 48.2 0.9 1.7 1 1 1 2 2 2 1 Cornichon protein PET122 PF05476.6 AIO01278.1 - 0.076 12.2 0.1 0.1 11.8 0.1 1.2 1 0 0 1 1 1 0 PET122 Herpes_US9 PF06072.6 AIO01278.1 - 0.84 9.5 3.3 0.81 9.5 0.5 2.3 2 1 0 2 2 2 0 Alphaherpesvirus tegument protein US9 DUF4014 PF13198.1 AIO01278.1 - 3.1 8.2 4.9 36 4.8 0.4 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF4014) Shugoshin_N PF07558.6 AIO01279.1 - 0.00024 20.7 0.5 0.00079 19.0 0.4 1.9 1 0 0 1 1 1 1 Shugoshin N-terminal coiled-coil region DUF1192 PF06698.6 AIO01279.1 - 0.00056 19.6 0.8 2 8.2 0.0 3.6 3 0 0 3 3 3 1 Protein of unknown function (DUF1192) HALZ PF02183.13 AIO01279.1 - 0.013 15.2 5.1 7.5 6.3 0.4 3.4 3 0 0 3 3 3 0 Homeobox associated leucine zipper Fez1 PF06818.10 AIO01279.1 - 0.024 14.6 4.6 0.036 14.0 3.2 1.3 1 0 0 1 1 1 0 Fez1 Lzipper-MIP1 PF14389.1 AIO01279.1 - 0.025 14.6 4.4 0.059 13.4 0.1 2.6 1 1 1 2 2 2 0 Leucine-zipper of ternary complex factor MIP1 bZIP_1 PF00170.16 AIO01279.1 - 0.053 13.4 6.8 0.09 12.7 0.3 3.2 3 0 0 3 3 3 0 bZIP transcription factor DUF972 PF06156.8 AIO01279.1 - 0.098 13.0 4.8 5.6 7.3 0.3 3.4 1 1 2 3 3 3 0 Protein of unknown function (DUF972) NEMO PF11577.3 AIO01279.1 - 0.11 12.2 2.2 6.3 6.6 0.2 2.5 2 0 0 2 2 2 0 NF-kappa-B essential modulator NEMO CorA PF01544.13 AIO01279.1 - 0.13 11.2 5.5 0.51 9.3 1.9 2.1 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein Mto2_bdg PF12808.2 AIO01279.1 - 0.17 11.9 6.6 3.2 7.9 0.2 2.7 2 0 0 2 2 2 0 Micro-tubular organiser Mto1 C-term Mto2-binding region Med9 PF07544.8 AIO01279.1 - 0.52 10.0 4.0 16 5.2 0.0 2.9 3 0 0 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 CtIP_N PF10482.4 AIO01279.1 - 1.1 9.0 5.0 5.5 6.7 0.4 2.9 2 1 1 3 3 3 0 Tumour-suppressor protein CtIP N-terminal domain DUF904 PF06005.7 AIO01279.1 - 2.1 8.7 8.0 8.7 6.7 3.1 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF904) bZIP_2 PF07716.10 AIO01279.1 - 3.6 7.4 9.1 6 6.7 0.7 3.3 3 0 0 3 3 3 0 Basic region leucine zipper IncA PF04156.9 AIO01279.1 - 4.2 6.9 11.8 3.9 7.0 0.4 2.3 2 0 0 2 2 2 0 IncA protein CENP-Q PF13094.1 AIO01279.1 - 5.3 7.0 8.4 2.4 8.1 0.3 2.8 1 1 1 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit Myosin_head PF00063.16 AIO01281.1 - 1.2e-168 562.3 0.1 4.4e-168 560.4 0.0 1.7 1 1 0 1 1 1 1 Myosin head (motor domain) UBA PF00627.26 AIO01281.1 - 7.6e-07 28.7 0.0 0.00064 19.4 0.0 2.9 2 0 0 2 2 2 2 UBA/TS-N domain AAA_22 PF13401.1 AIO01281.1 - 0.00089 19.4 0.3 0.02 15.0 0.0 3.2 3 0 0 3 3 3 1 AAA domain CUE PF02845.11 AIO01281.1 - 0.0049 16.3 0.2 1.2 8.6 0.2 3.4 3 0 0 3 3 3 1 CUE domain Mg_chelatase PF01078.16 AIO01281.1 - 0.017 14.3 0.0 0.046 12.8 0.0 1.7 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Myosin_N PF02736.14 AIO01281.1 - 0.079 12.6 0.1 0.26 10.9 0.1 1.9 1 0 0 1 1 1 0 Myosin N-terminal SH3-like domain Peptidase_C54 PF03416.14 AIO01283.1 - 1.6e-45 155.4 0.0 2e-45 155.1 0.0 1.1 1 0 0 1 1 1 1 Peptidase family C54 Ribosomal_L2_C PF03947.13 AIO01284.1 - 4.6e-40 136.4 2.0 6.2e-40 136.0 0.8 1.6 2 0 0 2 2 2 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.18 AIO01284.1 - 3.5e-13 49.3 0.0 1.2e-12 47.6 0.0 1.9 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain COPIIcoated_ERV PF07970.7 AIO01285.1 - 6.2e-36 124.0 0.5 8.4e-36 123.6 0.4 1.1 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.1 AIO01285.1 - 1.5e-24 85.7 0.6 2.7e-24 84.9 0.4 1.4 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) Helicase_C_3 PF13625.1 AIO01286.1 - 9.2e-14 51.3 0.1 1.9e-13 50.2 0.1 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 AIO01286.1 - 5.3e-13 49.1 0.0 1.4e-12 47.8 0.0 1.7 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_C PF00271.26 AIO01286.1 - 2.9e-11 43.0 0.1 7.7e-11 41.7 0.1 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 AIO01286.1 - 2.7e-08 32.9 0.0 9.9e-07 27.8 0.0 2.4 2 0 0 2 2 2 1 SNF2 family N-terminal domain HECT PF00632.20 AIO01287.1 - 6.7e-42 143.7 0.1 1.4e-41 142.7 0.0 1.5 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) SPRY PF00622.23 AIO01287.1 - 4.6e-29 101.0 0.1 2.4e-08 34.0 0.0 4.6 4 0 0 4 4 4 4 SPRY domain ZZ PF00569.12 AIO01287.1 - 0.0093 15.4 10.2 0.025 14.0 7.1 1.7 1 0 0 1 1 1 1 Zinc finger, ZZ type PIN_4 PF13638.1 AIO01288.1 - 0.0022 18.1 0.0 0.012 15.7 0.0 2.2 1 1 0 1 1 1 1 PIN domain PG_binding_1 PF01471.13 AIO01290.1 - 0.015 15.2 1.7 0.048 13.6 0.0 2.6 4 0 0 4 4 4 0 Putative peptidoglycan binding domain cNMP_binding PF00027.24 AIO01291.1 - 1e-21 76.5 0.1 6.6e-09 35.4 0.0 3.9 3 1 0 3 3 3 2 Cyclic nucleotide-binding domain 7TM_GPCR_Sri PF10327.4 AIO01291.1 - 0.0083 15.1 0.1 0.015 14.2 0.0 1.3 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Sri Gar1 PF04410.9 AIO01292.1 - 6.7e-26 90.5 0.0 9.2e-26 90.1 0.0 1.2 1 0 0 1 1 1 1 Gar1/Naf1 RNA binding region Glycos_transf_2 PF00535.21 AIO01293.1 - 1.1e-05 25.1 0.0 2.3e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 LysM PF01476.15 AIO01296.1 - 7.8e-08 32.0 0.1 0.029 14.2 0.0 3.0 3 0 0 3 3 3 2 LysM domain HTH_AsnC-type PF13404.1 AIO01296.1 - 0.033 13.7 2.0 2.6 7.6 0.0 3.1 3 0 0 3 3 3 0 AsnC-type helix-turn-helix domain DUF3606 PF12244.3 AIO01296.1 - 0.092 12.3 1.0 1.5 8.5 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3606) HTH_23 PF13384.1 AIO01296.1 - 0.12 12.0 0.0 2 8.2 0.0 2.8 3 0 0 3 3 3 0 Homeodomain-like domain Herpes_UL52 PF03121.10 AIO01298.1 - 1.8e-15 56.4 0.1 1.3e-14 53.6 0.0 2.4 2 0 0 2 2 2 1 Herpesviridae UL52/UL70 DNA primase Ribonucleas_3_3 PF14622.1 AIO01299.1 - 0.021 14.7 0.0 0.31 11.0 0.0 2.3 2 0 0 2 2 2 0 Ribonuclease-III-like WD40 PF00400.27 AIO01301.1 - 5.5e-44 146.5 15.9 7e-12 44.7 0.3 7.5 8 0 0 8 8 8 7 WD domain, G-beta repeat BBS2_Mid PF14783.1 AIO01301.1 - 0.0009 18.9 0.0 0.51 10.1 0.0 3.1 2 1 1 3 3 3 2 Ciliary BBSome complex subunit 2, middle region DUF3616 PF12275.3 AIO01301.1 - 0.036 13.0 0.0 0.058 12.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3616) Sen15 PF09631.5 AIO01301.1 - 0.12 12.6 0.0 0.47 10.7 0.0 2.0 2 0 0 2 2 2 0 Sen15 protein HEAT PF02985.17 AIO01302.1 - 0.00036 20.3 7.0 0.22 11.6 0.0 5.5 7 0 0 7 7 7 2 HEAT repeat UVR PF02151.14 AIO01302.1 - 0.0025 17.2 7.8 0.011 15.2 0.3 2.7 2 0 0 2 2 2 2 UvrB/uvrC motif HEAT_EZ PF13513.1 AIO01302.1 - 3.7 8.1 6.3 21 5.7 0.0 3.8 4 0 0 4 4 4 0 HEAT-like repeat DUF1675 PF07897.6 AIO01303.1 - 0.044 13.6 0.4 0.053 13.3 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) RecX PF02631.11 AIO01303.1 - 0.11 12.6 0.6 0.2 11.8 0.4 1.4 1 0 0 1 1 1 0 RecX family PPR_3 PF13812.1 AIO01304.1 - 0.021 15.0 0.0 0.67 10.3 0.0 3.5 2 0 0 2 2 2 0 Pentatricopeptide repeat domain Zip PF02535.17 AIO01305.1 - 1e-11 44.4 14.6 3.9e-07 29.3 1.0 3.3 2 1 1 3 3 3 3 ZIP Zinc transporter OppC_N PF12911.2 AIO01305.1 - 0.11 11.8 1.6 0.2 11.0 0.1 2.1 2 0 0 2 2 2 0 N-terminal TM domain of oligopeptide transport permease C RE_MjaI PF09568.5 AIO01306.1 - 0.019 14.5 0.0 0.03 13.8 0.0 1.2 1 0 0 1 1 1 0 MjaI restriction endonuclease DUF2793 PF10983.3 AIO01306.1 - 0.11 12.2 0.4 0.27 11.0 0.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2793) CEP19 PF14933.1 AIO01308.1 - 3.4e-49 167.1 0.0 4.9e-49 166.6 0.0 1.2 1 0 0 1 1 1 1 CEP19-like protein Nop PF01798.13 AIO01309.1 - 1.9e-17 62.9 0.0 2.8e-17 62.4 0.0 1.3 1 0 0 1 1 1 1 Putative snoRNA binding domain NOSIC PF08060.8 AIO01309.1 - 1.3e-14 53.7 0.1 2.6e-14 52.7 0.1 1.6 1 0 0 1 1 1 1 NOSIC (NUC001) domain Aminotran_1_2 PF00155.16 AIO01309.1 - 0.029 13.3 0.0 0.038 12.9 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class I and II Ank_2 PF12796.2 AIO01310.1 - 5.7e-14 52.2 0.2 3.1e-11 43.4 0.0 2.4 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 AIO01310.1 - 1e-13 50.3 2.6 2.3e-09 36.5 0.2 3.8 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.1 AIO01310.1 - 1.3e-08 34.7 1.0 0.0002 21.4 0.2 3.8 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 AIO01310.1 - 8.8e-08 31.6 1.6 0.0024 17.9 0.1 3.5 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.1 AIO01310.1 - 3.4e-07 30.5 0.1 0.0073 16.7 0.1 3.0 2 1 0 2 2 2 2 Ankyrin repeats (many copies) RMMBL PF07521.7 AIO01310.1 - 4.3 7.2 5.7 1.6 8.6 0.1 2.9 3 0 0 3 3 3 0 RNA-metabolising metallo-beta-lactamase DUF1762 PF08574.5 AIO01311.1 - 0.00011 22.5 1.5 0.00011 22.5 1.1 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF1762) LBP_BPI_CETP PF01273.20 AIO01312.1 - 0.11 11.7 0.1 1.5 8.1 0.0 2.3 2 0 0 2 2 2 0 LBP / BPI / CETP family, N-terminal domain Tetraspannin PF00335.15 AIO01313.1 - 5.7e-10 38.8 16.8 8.1e-10 38.3 11.6 1.2 1 0 0 1 1 1 1 Tetraspanin family DUF3762 PF12591.3 AIO01315.1 - 0.05 13.6 0.1 0.12 12.3 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3762) Wzz PF02706.10 AIO01315.1 - 0.061 13.1 0.1 0.12 12.1 0.1 1.5 1 0 0 1 1 1 0 Chain length determinant protein Peptidase_M14 PF00246.19 AIO01316.1 - 3e-22 79.5 0.0 8.4e-22 78.0 0.0 1.7 2 0 0 2 2 2 1 Zinc carboxypeptidase zf-DHHC PF01529.15 AIO01319.1 - 8.6e-46 155.4 1.5 1.4e-45 154.8 1.1 1.3 1 0 0 1 1 1 1 DHHC palmitoyltransferase A_deamin PF02137.13 AIO01320.1 - 9.8e-28 97.4 0.0 1.3e-27 97.0 0.0 1.2 1 0 0 1 1 1 1 Adenosine-deaminase (editase) domain GST_N_3 PF13417.1 AIO01321.1 - 6.2e-34 116.0 0.1 1.4e-15 57.2 0.0 2.7 2 0 0 2 2 2 2 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 AIO01321.1 - 8.4e-28 96.1 0.1 7.2e-14 51.5 0.0 2.4 2 0 0 2 2 2 2 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 AIO01321.1 - 1.1e-16 60.7 0.4 2.2e-08 34.1 0.0 2.9 3 0 0 3 3 3 2 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 AIO01321.1 - 7.5e-14 51.3 2.2 4.5e-06 26.4 0.1 2.6 2 0 0 2 2 2 2 Glutathione S-transferase, C-terminal domain Glutaredoxin PF00462.19 AIO01321.1 - 2.9e-10 39.9 0.7 4e-07 29.9 0.2 2.4 2 0 0 2 2 2 2 Glutaredoxin GST_C PF00043.20 AIO01321.1 - 6.7e-07 29.2 0.4 0.0036 17.2 0.1 2.6 2 0 0 2 2 2 2 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 AIO01321.1 - 7.2e-07 29.6 0.1 0.022 15.2 0.0 2.5 2 0 0 2 2 2 2 Glutathione S-transferase, C-terminal domain YPEB PF14620.1 AIO01321.1 - 0.23 10.4 0.0 0.39 9.6 0.0 1.3 1 0 0 1 1 1 0 YpeB sporulation RRM_1 PF00076.17 AIO01323.1 - 5.6e-11 41.9 0.0 8.9e-11 41.2 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 AIO01323.1 - 1.7e-07 31.0 0.0 2.7e-07 30.4 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 AIO01323.1 - 1.9e-05 24.4 0.0 3.8e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 AIO01323.1 - 0.00042 20.1 0.1 0.0014 18.4 0.0 1.8 1 1 1 2 2 2 1 RNA binding motif Mpv17_PMP22 PF04117.7 AIO01324.1 - 3.8e-13 48.8 0.6 1.1e-12 47.3 0.4 1.8 1 0 0 1 1 1 1 Mpv17 / PMP22 family NtA PF03146.10 AIO01324.1 - 0.0028 17.3 0.0 0.62 9.7 0.0 2.4 2 0 0 2 2 2 2 Agrin NtA domain WD40 PF00400.27 AIO01325.1 - 7.5e-27 92.1 6.7 1.4e-05 24.7 0.0 6.8 6 0 0 6 6 6 6 WD domain, G-beta repeat Cytochrom_D1 PF02239.11 AIO01325.1 - 0.026 12.8 0.0 0.67 8.1 0.0 2.2 2 0 0 2 2 2 0 Cytochrome D1 heme domain Sugar_tr PF00083.19 AIO01326.1 - 3.5e-132 441.1 25.9 4.1e-132 440.9 18.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 AIO01326.1 - 8.7e-16 57.5 23.2 8.7e-16 57.5 16.1 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily DUF3169 PF11368.3 AIO01326.1 - 0.03 13.5 0.4 0.03 13.5 0.2 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF3169) DUF2207 PF09972.4 AIO01326.1 - 0.98 7.9 5.2 1.5 7.3 0.1 2.8 3 1 0 3 3 3 0 Predicted membrane protein (DUF2207) Autophagy_N PF03986.8 AIO01327.1 - 5.6e-28 97.5 0.2 8.7e-28 96.9 0.1 1.3 1 0 0 1 1 1 1 Autophagocytosis associated protein (Atg3), N-terminal domain Autophagy_act_C PF03987.10 AIO01327.1 - 7.9e-25 86.8 3.1 1.6e-24 85.8 2.1 1.5 1 0 0 1 1 1 1 Autophagocytosis associated protein, active-site domain Autophagy_Cterm PF10381.4 AIO01327.1 - 3.2e-12 45.3 0.9 6.9e-12 44.2 0.7 1.6 1 0 0 1 1 1 1 Autophagocytosis associated protein C-terminal ABC_tran PF00005.22 AIO01329.1 - 3.8e-44 150.3 0.0 9.8e-21 74.4 0.0 3.1 3 0 0 3 3 2 2 ABC transporter AAA_21 PF13304.1 AIO01329.1 - 9.7e-19 68.4 0.0 0.00019 21.4 0.0 4.3 3 1 0 4 4 4 4 AAA domain SMC_N PF02463.14 AIO01329.1 - 1.7e-10 40.5 2.5 0.00054 19.2 0.0 4.9 3 2 1 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 AIO01329.1 - 8.4e-08 31.6 0.3 0.0078 15.7 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain DUF258 PF03193.11 AIO01329.1 - 6.2e-07 28.7 0.1 0.01 15.0 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_17 PF13207.1 AIO01329.1 - 1.8e-06 28.7 1.0 0.0089 16.8 0.0 3.7 4 0 0 4 4 4 1 AAA domain SbcCD_C PF13558.1 AIO01329.1 - 5e-05 23.1 0.3 0.015 15.2 0.0 3.5 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_10 PF12846.2 AIO01329.1 - 0.00028 20.4 0.1 2.4 7.5 0.0 3.8 3 0 0 3 3 3 1 AAA-like domain AAA_14 PF13173.1 AIO01329.1 - 0.00061 19.6 0.2 1.9 8.4 0.0 3.2 3 0 0 3 3 2 2 AAA domain AAA_16 PF13191.1 AIO01329.1 - 0.00066 19.7 4.4 0.29 11.1 0.3 3.1 3 1 0 3 3 2 2 AAA ATPase domain AAA_15 PF13175.1 AIO01329.1 - 0.00069 18.7 0.8 8.9 5.2 0.0 4.5 5 1 0 5 5 5 0 AAA ATPase domain RNA_helicase PF00910.17 AIO01329.1 - 0.00095 19.3 0.0 0.79 9.9 0.0 2.6 2 0 0 2 2 2 1 RNA helicase AAA_22 PF13401.1 AIO01329.1 - 0.001 19.2 0.0 2.1 8.4 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA PF00004.24 AIO01329.1 - 0.0011 19.1 0.1 1.5 9.0 0.0 3.4 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 AIO01329.1 - 0.0026 17.4 0.1 1.3 8.7 0.0 2.7 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) MMR_HSR1 PF01926.18 AIO01329.1 - 0.004 17.0 0.1 0.74 9.7 0.1 2.9 2 1 0 2 2 2 1 50S ribosome-binding GTPase Miro PF08477.8 AIO01329.1 - 0.0042 17.5 0.3 2.6 8.5 0.0 3.2 3 0 0 3 3 3 1 Miro-like protein AAA_33 PF13671.1 AIO01329.1 - 0.0055 16.5 0.0 1.2 9.0 0.0 3.0 3 0 0 3 3 3 1 AAA domain ABC_tran_2 PF12848.2 AIO01329.1 - 0.0062 16.3 2.6 0.0062 16.3 1.8 3.5 3 0 0 3 3 3 1 ABC transporter AAA_18 PF13238.1 AIO01329.1 - 0.024 14.9 2.2 2.7 8.3 0.0 3.2 3 0 0 3 3 2 0 AAA domain NACHT PF05729.7 AIO01329.1 - 0.036 13.7 0.0 5.1 6.7 0.0 2.7 2 0 0 2 2 2 0 NACHT domain Mad3_BUB1_II PF08171.6 AIO01329.1 - 0.037 13.9 0.1 0.096 12.5 0.0 1.7 1 0 0 1 1 1 0 Mad3/BUB1 homology region 2 AAA_28 PF13521.1 AIO01329.1 - 0.069 13.1 7.0 0.33 10.9 0.0 3.0 3 0 0 3 3 2 0 AAA domain Mg_chelatase PF01078.16 AIO01329.1 - 0.071 12.2 0.5 3.2 6.8 0.1 2.6 2 1 0 2 2 2 0 Magnesium chelatase, subunit ChlI NTPase_1 PF03266.10 AIO01329.1 - 0.074 12.7 0.1 2 8.1 0.0 2.7 3 0 0 3 3 2 0 NTPase AAA_23 PF13476.1 AIO01329.1 - 0.51 10.6 0.0 0.51 10.6 0.0 4.6 5 1 0 5 5 3 0 AAA domain HSP90 PF00183.13 AIO01330.1 - 2.4e-260 864.4 31.8 2.8e-260 864.2 22.1 1.0 1 0 0 1 1 1 1 Hsp90 protein HATPase_c_3 PF13589.1 AIO01330.1 - 2.2e-13 50.0 0.3 1.2e-12 47.6 0.2 2.4 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 AIO01330.1 - 5e-13 48.7 0.1 9e-13 47.9 0.1 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Ribosomal_S20p PF01649.13 AIO01330.1 - 0.01 16.1 1.1 0.97 9.8 0.6 3.2 2 0 0 2 2 2 0 Ribosomal protein S20 LOH1CR12 PF10158.4 AIO01330.1 - 0.026 14.3 0.3 0.092 12.5 0.2 2.0 1 0 0 1 1 1 0 Tumour suppressor protein WD40 PF00400.27 AIO01331.1 - 3e-14 52.2 5.3 2.7e-06 27.0 0.0 5.7 6 0 0 6 6 6 4 WD domain, G-beta repeat X PF00739.14 AIO01332.1 - 0.025 14.4 0.1 0.047 13.5 0.0 1.5 1 0 0 1 1 1 0 Trans-activation protein X GcpE PF04551.9 AIO01332.1 - 0.17 10.6 0.0 0.32 9.7 0.0 1.3 1 1 0 1 1 1 0 GcpE protein Abhydrolase_5 PF12695.2 AIO01334.1 - 3.1e-20 72.4 0.0 4.3e-20 71.9 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 AIO01334.1 - 5.1e-16 59.2 1.3 9.8e-11 41.9 0.3 2.7 2 1 1 3 3 3 2 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 AIO01334.1 - 1.5e-09 37.7 0.2 8.9e-06 25.4 0.3 2.3 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_2 PF02230.11 AIO01334.1 - 3.2e-06 26.7 0.0 0.00082 18.8 0.0 2.6 1 1 0 1 1 1 1 Phospholipase/Carboxylesterase Peptidase_S9 PF00326.16 AIO01334.1 - 4.8e-05 22.6 0.1 0.049 12.8 0.0 2.3 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_3 PF07859.8 AIO01334.1 - 0.011 15.2 0.1 0.02 14.4 0.1 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold Hydrolase_4 PF12146.3 AIO01334.1 - 0.017 14.9 0.1 0.065 13.0 0.1 2.0 2 0 0 2 2 2 0 Putative lysophospholipase FSH1 PF03959.8 AIO01334.1 - 0.022 14.2 0.0 0.04 13.3 0.0 1.4 1 0 0 1 1 1 0 Serine hydrolase (FSH1) UPF0227 PF05728.7 AIO01334.1 - 0.044 13.5 0.1 7.3 6.2 0.0 2.3 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0227) LIP PF03583.9 AIO01334.1 - 0.088 11.9 0.2 0.26 10.4 0.0 1.7 2 0 0 2 2 2 0 Secretory lipase Lipase_3 PF01764.20 AIO01334.1 - 0.096 12.2 0.0 0.19 11.3 0.0 1.5 1 0 0 1 1 1 0 Lipase (class 3) MutS_V PF00488.16 AIO01335.1 - 8.9e-80 267.4 0.0 1.5e-79 266.6 0.0 1.3 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 AIO01335.1 - 1.2e-28 100.3 0.6 1.2e-28 100.3 0.4 1.7 2 0 0 2 2 2 1 MutS domain III MutS_IV PF05190.13 AIO01335.1 - 1.4e-15 57.1 1.2 3.6e-15 55.9 0.8 1.6 1 0 0 1 1 1 1 MutS family domain IV AAA_29 PF13555.1 AIO01335.1 - 0.036 13.6 0.1 0.25 10.8 0.1 2.2 2 0 0 2 2 2 0 P-loop containing region of AAA domain FAD_binding_7 PF03441.9 AIO01341.1 - 3e-98 328.4 1.1 4.2e-98 327.9 0.7 1.2 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.13 AIO01341.1 - 8.2e-30 103.7 0.0 1.6e-29 102.7 0.0 1.4 1 0 0 1 1 1 1 DNA photolyase TC1 PF15063.1 AIO01343.1 - 0.051 13.1 2.2 10 5.7 0.0 3.2 3 0 0 3 3 3 0 Thyroid cancer protein 1 SET PF00856.23 AIO01345.1 - 2.8e-08 34.2 0.0 1.4e-07 31.9 0.0 2.0 2 0 0 2 2 2 1 SET domain ADH_N PF08240.7 AIO01346.1 - 6.1e-24 83.8 0.0 1.4e-23 82.7 0.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 AIO01346.1 - 1.8e-17 63.1 0.0 2.9e-17 62.4 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 AIO01346.1 - 0.0013 19.6 0.0 0.0034 18.2 0.0 1.6 1 1 1 2 2 2 1 Zinc-binding dehydrogenase LRR_4 PF12799.2 AIO01347.1 - 3.3e-23 80.8 0.0 0.00016 21.2 0.0 9.0 6 3 0 7 7 7 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 AIO01347.1 - 2.9e-12 46.1 12.6 0.11 12.3 0.0 7.4 6 1 2 9 9 9 6 Leucine rich repeat LRR_6 PF13516.1 AIO01347.1 - 0.14 12.2 17.7 1.3 9.3 0.0 7.9 9 1 0 9 9 9 0 Leucine Rich repeat LRR_1 PF00560.28 AIO01347.1 - 2.2 8.6 19.0 20 5.7 0.0 8.8 9 1 0 9 9 9 0 Leucine Rich Repeat NifU PF01106.12 AIO01349.1 - 5.1e-15 54.9 0.0 9.8e-15 54.0 0.0 1.5 1 0 0 1 1 1 1 NifU-like domain Nfu_N PF08712.6 AIO01349.1 - 1.4e-10 40.6 0.1 1.4e-08 34.1 0.0 2.5 2 0 0 2 2 2 2 Scaffold protein Nfu/NifU N terminal DUF677 PF05055.7 AIO01350.1 - 0.22 10.1 0.3 0.38 9.3 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF677) RtcB PF01139.12 AIO01351.1 - 8.4e-92 308.3 0.0 9.4e-92 308.1 0.0 1.0 1 0 0 1 1 1 1 tRNA-splicing ligase RtcB DYW_deaminase PF14432.1 AIO01352.1 - 0.2 11.6 2.6 0.4 10.6 1.8 1.5 1 0 0 1 1 1 0 DYW family of nucleic acid deaminases FYVE PF01363.16 AIO01352.1 - 0.29 11.0 19.8 1.6 8.7 13.7 1.9 1 1 0 1 1 1 0 FYVE zinc finger WD40 PF00400.27 AIO01353.1 - 0.022 14.6 0.7 26 4.8 0.0 4.2 4 0 0 4 4 4 0 WD domain, G-beta repeat SynMuv_product PF06047.6 AIO01354.1 - 2.5e-14 52.8 0.9 5.9e-14 51.6 0.6 1.6 1 0 0 1 1 1 1 Ras-induced vulval development antagonist BRE1 PF08647.6 AIO01356.1 - 2.4e-21 75.4 8.5 2.4e-21 75.4 5.9 10.5 4 2 8 13 13 13 2 BRE1 E3 ubiquitin ligase AAA_13 PF13166.1 AIO01356.1 - 8.3e-05 21.2 16.9 8.3e-05 21.2 11.7 6.1 1 1 4 6 6 6 4 AAA domain DUF4094 PF13334.1 AIO01356.1 - 0.0031 17.8 4.2 0.0031 17.8 2.9 8.5 5 3 4 9 9 9 1 Domain of unknown function (DUF4094) Reo_sigmaC PF04582.7 AIO01356.1 - 0.029 13.5 42.9 0.014 14.5 1.2 6.9 2 1 3 6 6 6 0 Reovirus sigma C capsid protein rve_3 PF13683.1 AIO01356.1 - 0.066 12.7 1.6 3.2 7.3 0.1 3.8 2 1 0 2 2 2 0 Integrase core domain Spc7 PF08317.6 AIO01356.1 - 2 6.9 126.7 0.012 14.2 11.3 7.0 2 1 4 7 7 7 0 Spc7 kinetochore protein IGR PF09597.5 AIO01357.1 - 0.00066 19.5 0.0 0.0012 18.6 0.0 1.4 1 0 0 1 1 1 1 IGR protein motif TPR_7 PF13176.1 AIO01358.1 - 0.0068 16.1 2.2 1.6 8.7 0.1 4.3 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_2 PF07719.12 AIO01358.1 - 0.012 15.4 0.2 7.1 6.8 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_21 PF09976.4 AIO01358.1 - 0.017 15.0 0.2 30 4.5 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.23 AIO01358.1 - 0.057 13.0 0.0 13 5.6 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat CDT1 PF08839.6 AIO01358.1 - 0.12 12.3 0.0 0.42 10.5 0.0 1.9 2 0 0 2 2 2 0 DNA replication factor CDT1 like IFT57 PF10498.4 AIO01360.1 - 3.4e-69 233.3 7.0 3.8e-69 233.1 4.8 1.0 1 0 0 1 1 1 1 Intra-flagellar transport protein 57 AAA_13 PF13166.1 AIO01360.1 - 0.0013 17.3 5.3 0.0014 17.2 3.6 1.1 1 0 0 1 1 1 1 AAA domain mRNA_stabil PF13929.1 AIO01360.1 - 0.0019 17.1 0.2 0.0063 15.5 0.0 1.7 1 1 0 2 2 2 1 mRNA stabilisation Spc7 PF08317.6 AIO01360.1 - 0.0072 15.0 7.2 0.01 14.4 5.0 1.3 1 0 0 1 1 1 1 Spc7 kinetochore protein V_ATPase_I PF01496.14 AIO01360.1 - 0.018 12.8 7.5 0.023 12.5 5.2 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Laminin_II PF06009.7 AIO01360.1 - 0.019 14.7 10.1 0.61 9.8 0.3 2.4 1 1 1 2 2 2 0 Laminin Domain II Apolipoprotein PF01442.13 AIO01360.1 - 0.028 13.9 11.4 0.037 13.5 7.4 1.6 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain DUF1664 PF07889.7 AIO01360.1 - 0.051 13.3 10.4 0.14 11.9 2.4 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) DUF745 PF05335.8 AIO01360.1 - 0.087 12.3 9.2 0.68 9.4 4.1 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF745) AKNA PF12443.3 AIO01360.1 - 0.16 12.0 9.3 0.43 10.6 1.2 2.5 1 1 1 2 2 2 0 AT-hook-containing transcription factor IncA PF04156.9 AIO01360.1 - 0.22 11.0 13.4 0.27 10.8 8.2 1.8 1 1 1 2 2 2 0 IncA protein TPR_MLP1_2 PF07926.7 AIO01360.1 - 0.28 10.9 11.0 0.67 9.7 7.3 1.9 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein Syntaxin_2 PF14523.1 AIO01360.1 - 0.39 10.7 8.0 0.88 9.6 3.7 2.3 1 1 1 2 2 2 0 Syntaxin-like protein GAS PF13851.1 AIO01360.1 - 0.42 9.7 10.4 0.23 10.6 5.5 1.7 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding DUF4315 PF14193.1 AIO01360.1 - 0.7 9.8 5.2 2.9 7.9 3.6 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF4315) Fzo_mitofusin PF04799.8 AIO01360.1 - 0.71 9.2 8.9 0.67 9.3 5.0 1.8 1 1 1 2 2 2 0 fzo-like conserved region WXG100 PF06013.7 AIO01360.1 - 0.81 9.7 8.2 12 5.9 4.5 2.9 2 1 0 2 2 2 0 Proteins of 100 residues with WXG Atg14 PF10186.4 AIO01360.1 - 1.3 7.8 11.9 3.1 6.6 1.4 2.1 1 1 1 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 Ead_Ea22 PF13935.1 AIO01360.1 - 1.4 9.2 6.1 6.5 7.0 4.2 2.3 1 1 0 1 1 1 0 Ead/Ea22-like protein Mnd1 PF03962.10 AIO01360.1 - 3.5 7.2 11.0 9.4 5.8 7.6 1.8 1 1 0 1 1 1 0 Mnd1 family DUF883 PF05957.8 AIO01360.1 - 5.6 7.4 7.3 29 5.1 2.7 2.7 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) DUF4200 PF13863.1 AIO01360.1 - 6.2 6.7 13.0 27 4.7 7.3 2.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4200) CAP_N PF01213.14 AIO01361.1 - 0.091 12.0 0.1 0.14 11.4 0.1 1.2 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal EF-hand_7 PF13499.1 AIO01362.1 - 0.0048 17.0 0.0 0.0078 16.3 0.0 1.3 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.1 AIO01362.1 - 0.014 15.2 0.0 0.075 12.9 0.0 2.2 1 1 0 1 1 1 0 EF-hand domain EF-hand_1 PF00036.27 AIO01362.1 - 0.03 13.6 0.0 0.26 10.6 0.0 2.3 1 1 1 2 2 2 0 EF hand DUF2502 PF10697.4 AIO01364.1 - 7.9 6.6 8.6 2 8.5 0.9 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2502) WD40 PF00400.27 AIO01365.1 - 0.024 14.5 1.1 10 6.1 0.1 4.2 4 0 0 4 4 4 0 WD domain, G-beta repeat He_PIG_assoc PF10632.4 AIO01365.1 - 0.026 13.8 0.1 0.14 11.5 0.0 2.3 1 0 0 1 1 1 0 He_PIG associated, NEW1 domain of bacterial glycohydrolase ERG4_ERG24 PF01222.12 AIO01366.1 - 2.9e-107 358.8 24.5 3.4e-107 358.6 17.0 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family FSIP1 PF15554.1 AIO01366.1 - 0.21 10.3 1.6 0.29 9.8 1.1 1.1 1 0 0 1 1 1 0 FSIP1 family Corona_nucleoca PF00937.13 AIO01366.1 - 0.35 9.7 5.2 0.5 9.2 3.6 1.2 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein DUF4131 PF13567.1 AIO01366.1 - 7.8 5.8 10.3 2.7 7.3 0.2 3.1 3 1 0 3 3 3 0 Domain of unknown function (DUF4131) TPR_11 PF13414.1 AIO01368.1 - 0.0013 18.2 8.4 0.0031 17.1 1.1 2.7 1 1 1 2 2 2 2 TPR repeat TPR_2 PF07719.12 AIO01368.1 - 0.0065 16.3 5.3 0.67 10.0 0.0 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.23 AIO01368.1 - 0.0072 15.8 3.6 0.75 9.5 0.0 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat Apc3 PF12895.2 AIO01368.1 - 0.0077 16.3 3.1 0.015 15.3 2.2 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.1 AIO01368.1 - 0.037 14.3 0.3 0.12 12.7 0.2 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat DUF3425 PF11905.3 AIO01368.1 - 0.086 12.7 0.1 0.35 10.7 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3425) PTR2 PF00854.16 AIO01369.1 - 2.4e-18 66.0 2.8 1.9e-14 53.2 0.0 3.0 2 1 0 2 2 2 2 POT family MFS_1 PF07690.11 AIO01369.1 - 3.2e-07 29.3 36.5 2.6e-05 23.1 10.9 2.9 2 1 0 2 2 2 2 Major Facilitator Superfamily Ribosomal_L6e PF01159.14 AIO01370.1 - 5e-33 113.5 0.8 3.1e-32 111.0 0.5 2.0 1 1 0 1 1 1 1 Ribosomal protein L6e KOW PF00467.24 AIO01370.1 - 0.00049 19.7 0.0 0.002 17.7 0.0 2.0 1 1 1 2 2 2 1 KOW motif OAD_gamma PF04277.8 AIO01370.1 - 5.5 7.4 10.9 0.64 10.4 4.0 2.0 2 0 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain WD40 PF00400.27 AIO01371.1 - 6.4e-17 60.7 5.8 8.3e-06 25.4 0.2 4.5 4 0 0 4 4 4 3 WD domain, G-beta repeat Rot1 PF10681.4 AIO01372.1 - 0.18 11.0 0.5 0.57 9.4 0.0 1.8 2 0 0 2 2 2 0 Chaperone for protein-folding within the ER, fungal Vitelline_membr PF10542.4 AIO01372.1 - 2.4 7.8 9.3 2.9 7.5 5.1 2.1 2 0 0 2 2 2 0 Vitelline membrane cysteine-rich region DUF2040 PF09745.4 AIO01374.1 - 0.0092 15.7 0.2 0.018 14.8 0.1 1.4 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 55 (DUF2040) Cyclin PF08613.6 AIO01376.1 - 1.2e-29 103.6 0.0 2.7e-29 102.5 0.0 1.6 1 1 0 1 1 1 1 Cyclin Cyclin_N PF00134.18 AIO01376.1 - 0.00019 20.9 0.1 0.00034 20.1 0.1 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain NIF PF03031.13 AIO01377.1 - 6.2e-20 71.4 0.8 9.1e-18 64.4 0.0 2.4 2 0 0 2 2 2 2 NLI interacting factor-like phosphatase Tubulin_C PF03953.12 AIO01379.1 - 2.3e-48 163.4 0.1 3.3e-48 162.8 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin PF00091.20 AIO01379.1 - 9.3e-09 35.4 0.0 1.9e-08 34.3 0.0 1.5 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Oxidored_FMN PF00724.15 AIO01380.1 - 1.2e-72 244.8 0.0 1.7e-72 244.3 0.0 1.2 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Pyr_redox_2 PF07992.9 AIO01380.1 - 4.9e-17 62.4 0.0 8.5e-14 51.9 0.0 2.6 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 AIO01380.1 - 2.2e-09 37.6 1.9 0.0094 16.0 0.0 3.4 2 1 2 4 4 4 3 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 AIO01380.1 - 1.2e-08 35.1 3.5 0.00081 19.7 1.3 3.6 3 1 0 3 3 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 AIO01380.1 - 1.9e-08 34.2 0.2 8.1e-08 32.1 0.0 2.2 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 AIO01380.1 - 9.3e-07 28.0 4.2 1.9e-06 27.0 0.6 2.9 3 0 0 3 3 3 1 FAD dependent oxidoreductase HI0933_like PF03486.9 AIO01380.1 - 1e-06 27.5 2.5 5.7e-06 25.0 0.4 2.4 1 1 1 2 2 2 1 HI0933-like protein K_oxygenase PF13434.1 AIO01380.1 - 1.2e-06 27.7 0.1 0.0014 17.6 0.0 2.4 1 1 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) FAD_oxidored PF12831.2 AIO01380.1 - 3e-06 26.5 1.3 4.8e-06 25.9 0.9 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 AIO01380.1 - 1.3e-05 24.2 2.0 2.7e-05 23.2 1.4 1.5 1 0 0 1 1 1 1 FAD binding domain 3HCDH_N PF02737.13 AIO01380.1 - 4.9e-05 23.0 0.4 0.0086 15.7 0.0 2.6 3 0 0 3 3 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FMO-like PF00743.14 AIO01380.1 - 5.4e-05 21.5 0.1 2.6 6.1 0.0 3.1 3 0 0 3 3 3 3 Flavin-binding monooxygenase-like GIDA PF01134.17 AIO01380.1 - 9.1e-05 21.4 2.8 0.00016 20.6 1.2 1.8 1 1 1 2 2 2 1 Glucose inhibited division protein A NAD_Gly3P_dh_N PF01210.18 AIO01380.1 - 0.00018 21.2 0.3 0.023 14.4 0.0 2.5 2 0 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus FAD_binding_3 PF01494.14 AIO01380.1 - 0.00036 19.6 1.4 0.0038 16.3 0.3 2.3 2 0 0 2 2 2 1 FAD binding domain NAD_binding_7 PF13241.1 AIO01380.1 - 0.00046 20.3 1.3 0.0097 16.1 0.1 2.6 2 1 0 2 2 2 1 Putative NAD(P)-binding Amino_oxidase PF01593.19 AIO01380.1 - 0.0005 19.2 0.3 0.03 13.4 0.1 2.2 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase Thi4 PF01946.12 AIO01380.1 - 0.00081 18.5 0.4 0.0035 16.4 0.1 1.9 2 0 0 2 2 2 1 Thi4 family NAD_binding_9 PF13454.1 AIO01380.1 - 0.002 17.9 3.1 0.18 11.5 0.2 3.2 3 0 0 3 3 3 1 FAD-NAD(P)-binding NAD_binding_10 PF13460.1 AIO01380.1 - 0.013 15.4 1.8 5.9 6.8 0.5 2.6 2 0 0 2 2 2 0 NADH(P)-binding NAD_binding_2 PF03446.10 AIO01380.1 - 0.027 14.3 0.1 0.55 10.0 0.0 2.5 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase UDPG_MGDP_dh_N PF03721.9 AIO01380.1 - 0.035 13.4 1.4 0.31 10.3 0.1 2.8 3 0 0 3 3 3 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain B12-binding PF02310.14 AIO01380.1 - 0.045 13.6 0.5 0.47 10.3 0.0 2.8 3 0 0 3 3 2 0 B12 binding domain PrpR_N PF06506.6 AIO01380.1 - 0.1 11.9 0.0 0.26 10.6 0.0 1.6 1 0 0 1 1 1 0 Propionate catabolism activator 2-Hacid_dh_C PF02826.14 AIO01380.1 - 0.11 11.5 0.0 6.3 5.9 0.0 2.3 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ApbA PF02558.11 AIO01380.1 - 0.13 11.7 1.0 7.4 5.9 0.4 2.9 2 1 0 2 2 2 0 Ketopantoate reductase PanE/ApbA Lycopene_cycl PF05834.7 AIO01380.1 - 0.39 9.5 1.5 0.69 8.7 0.3 1.9 2 1 0 2 2 2 0 Lycopene cyclase protein ThiF PF00899.16 AIO01380.1 - 0.78 9.5 3.2 3.7 7.3 0.1 2.9 3 0 0 3 3 3 0 ThiF family End3 PF12761.2 AIO01382.1 - 0.014 15.0 0.7 0.035 13.7 0.0 1.9 2 0 0 2 2 2 0 Actin cytoskeleton-regulatory complex protein END3 zf-Tim10_DDP PF02953.10 AIO01386.1 - 0.0058 15.8 2.8 0.24 10.6 2.0 2.4 1 1 0 1 1 1 1 Tim10/DDP family zinc finger DUF3874 PF12990.2 AIO01386.1 - 0.11 12.6 0.1 0.28 11.3 0.1 1.7 1 1 1 2 2 2 0 Domain of unknonw function from B. Theta Gene description (DUF3874) DnaJ PF00226.26 AIO01387.1 - 3.3e-22 77.9 0.4 5.2e-22 77.3 0.3 1.3 1 0 0 1 1 1 1 DnaJ domain IncA PF04156.9 AIO01387.1 - 0.57 9.7 0.0 0.57 9.7 0.0 4.3 4 0 0 4 4 4 0 IncA protein Ribosomal_S3_C PF00189.15 AIO01389.1 - 9.8e-16 57.7 1.0 9.8e-16 57.7 0.7 1.7 2 1 1 3 3 3 1 Ribosomal protein S3, C-terminal domain KH_2 PF07650.12 AIO01389.1 - 1.4e-08 34.1 0.3 3.3e-08 32.9 0.2 1.6 2 0 0 2 2 2 1 KH domain Rsc14 PF08586.5 AIO01391.1 - 0.35 11.3 1.8 20 5.7 0.1 2.3 1 1 1 2 2 2 0 RSC complex, Rsc14/Ldb7 subunit FIBP PF05427.6 AIO01392.1 - 0.00024 20.4 0.0 0.54 9.4 0.0 2.7 3 0 0 3 3 3 2 Acidic fibroblast growth factor binding (FIBP) AKAP_110 PF05716.8 AIO01392.1 - 1.4 6.8 3.9 4 5.3 0.2 2.4 2 0 0 2 2 2 0 A-kinase anchor protein 110 kDa (AKAP 110) WD40 PF00400.27 AIO01393.1 - 9.4e-08 31.6 5.9 0.0012 18.5 0.0 6.0 9 0 0 9 9 9 3 WD domain, G-beta repeat NAPRTase PF04095.11 AIO01394.1 - 5.2e-69 232.2 0.0 6.7e-69 231.8 0.0 1.1 1 0 0 1 1 1 1 Nicotinate phosphoribosyltransferase (NAPRTase) family Skp1 PF01466.14 AIO01396.1 - 4.7e-19 68.2 0.6 6.6e-19 67.7 0.4 1.1 1 0 0 1 1 1 1 Skp1 family, dimerisation domain E1-E2_ATPase PF00122.15 AIO01397.1 - 2.7e-48 164.0 1.3 2.7e-48 164.0 0.9 1.8 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 AIO01397.1 - 1.6e-38 132.0 5.9 1.6e-38 132.0 4.1 1.9 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 AIO01397.1 - 1.7e-15 58.0 0.1 0.00024 21.5 0.0 3.3 3 0 0 3 3 3 3 haloacid dehalogenase-like hydrolase HAD PF12710.2 AIO01397.1 - 3.8e-08 33.7 0.0 1.3e-07 31.9 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 AIO01397.1 - 1.9e-06 27.2 0.0 4.9e-06 25.9 0.0 1.7 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 AIO01397.1 - 1.1e-05 25.2 0.4 1.9e-05 24.3 0.3 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 AIO01397.1 - 3e-05 23.8 0.0 7.5e-05 22.6 0.0 1.6 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit PSP1 PF04468.7 AIO01398.1 - 2.1e-10 40.4 1.9 4.7e-10 39.3 0.1 2.3 3 0 0 3 3 3 1 PSP1 C-terminal conserved region PPTA PF01239.17 AIO01399.1 - 3.2e-27 92.7 11.7 2.3e-08 33.0 0.2 5.7 6 0 0 6 6 6 5 Protein prenyltransferase alpha subunit repeat TPR_17 PF13431.1 AIO01399.1 - 0.14 12.4 1.9 29 5.1 0.1 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TFIIA PF03153.8 AIO01400.1 - 2.1 8.1 6.5 2.7 7.7 4.5 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit TPR_MLP1_2 PF07926.7 AIO01401.1 - 0.022 14.5 1.5 0.056 13.1 1.0 1.7 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein Abhydrolase_5 PF12695.2 AIO01402.1 - 0.00016 21.4 0.0 0.00032 20.4 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 AIO01402.1 - 0.0083 15.3 0.0 0.013 14.7 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Voltage_CLC PF00654.15 AIO01403.1 - 4.2e-92 308.9 27.6 2.7e-91 306.2 16.5 2.3 2 1 0 2 2 2 2 Voltage gated chloride channel CBS PF00571.23 AIO01403.1 - 6.8e-18 64.1 1.4 9.9e-09 34.8 0.1 3.2 3 0 0 3 3 3 2 CBS domain YEATS PF03366.11 AIO01405.1 - 4.8e-09 35.8 0.0 9.2e-09 34.9 0.0 1.4 1 0 0 1 1 1 1 YEATS family LIF_OSM PF01291.12 AIO01405.1 - 0.11 12.3 0.0 0.22 11.4 0.0 1.5 1 0 0 1 1 1 0 LIF / OSM family Guanylate_kin PF00625.16 AIO01406.1 - 7.5e-49 165.6 0.0 8.9e-49 165.4 0.0 1.0 1 0 0 1 1 1 1 Guanylate kinase AAA_18 PF13238.1 AIO01406.1 - 9.6e-08 32.3 0.2 2.3e-07 31.1 0.1 1.7 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 AIO01406.1 - 9.7e-07 28.7 0.0 1.6e-06 28.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.18 AIO01406.1 - 2.2e-05 24.4 0.0 3.7e-05 23.6 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.1 AIO01406.1 - 5.6e-05 23.2 0.1 0.0022 18.1 0.0 2.3 2 1 0 2 2 2 1 AAA domain AAA_17 PF13207.1 AIO01406.1 - 0.00015 22.5 0.2 0.00029 21.6 0.1 1.6 1 1 0 1 1 1 1 AAA domain DUF258 PF03193.11 AIO01406.1 - 0.00084 18.5 0.0 0.0012 18.0 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 ADK PF00406.17 AIO01406.1 - 0.0014 18.4 0.3 0.093 12.6 0.1 2.2 2 0 0 2 2 2 1 Adenylate kinase Miro PF08477.8 AIO01406.1 - 0.0022 18.4 0.0 0.0038 17.6 0.0 1.4 1 1 0 1 1 1 1 Miro-like protein AAA_16 PF13191.1 AIO01406.1 - 0.013 15.4 0.0 0.034 14.1 0.0 1.7 2 0 0 2 2 2 0 AAA ATPase domain MobB PF03205.9 AIO01406.1 - 0.016 14.9 0.0 0.12 12.0 0.0 2.0 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_14 PF13173.1 AIO01406.1 - 0.037 13.9 0.0 0.13 12.2 0.0 1.8 1 1 0 2 2 2 0 AAA domain ABC_tran PF00005.22 AIO01406.1 - 0.063 13.5 0.1 0.14 12.4 0.1 2.0 1 1 0 1 1 1 0 ABC transporter CPT PF07931.7 AIO01406.1 - 0.093 12.3 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein zf-CW PF07496.10 AIO01407.1 - 1.3e-15 56.7 15.7 6.1e-12 45.0 4.8 3.6 3 0 0 3 3 3 2 CW-type Zinc Finger Yippee-Mis18 PF03226.9 AIO01408.1 - 0.048 13.6 6.1 3.5 7.7 0.0 3.2 3 0 0 3 3 3 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly DUF3395 PF11875.3 AIO01409.1 - 0.016 14.8 0.1 0.016 14.8 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3395) TIG PF01833.19 AIO01411.1 - 0.0003 20.7 0.5 0.007 16.3 0.0 2.5 2 0 0 2 2 2 1 IPT/TIG domain TIG PF01833.19 AIO01412.1 - 0.002 18.0 12.2 0.042 13.8 0.0 3.6 3 1 0 3 3 3 3 IPT/TIG domain PUF PF00806.14 AIO01413.1 - 1.2e-50 166.1 6.5 2.8e-06 26.5 0.4 8.4 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat CTD_bind PF04818.8 AIO01413.1 - 0.064 13.5 0.1 21 5.4 0.0 2.7 2 0 0 2 2 2 0 RNA polymerase II-binding domain. PAC2 PF09754.4 AIO01414.1 - 0.017 14.9 0.0 0.02 14.7 0.0 1.1 1 0 0 1 1 1 0 PAC2 family Ax_dynein_light PF10211.4 AIO01416.1 - 1.4e-38 132.6 10.1 2.1e-38 132.0 7.0 1.2 1 0 0 1 1 1 1 Axonemal dynein light chain AAA PF00004.24 AIO01418.1 - 1.4e-14 54.4 0.0 5.9e-10 39.4 0.0 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 AIO01418.1 - 3.3e-06 26.8 0.0 1.6e-05 24.6 0.0 2.2 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 AIO01418.1 - 3.2e-05 24.0 0.1 0.00065 19.7 0.0 2.9 3 0 0 3 3 3 1 AAA ATPase domain AAA_17 PF13207.1 AIO01418.1 - 8.2e-05 23.4 0.0 0.00018 22.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 AIO01418.1 - 0.00019 21.1 0.1 0.00072 19.2 0.0 2.0 2 0 0 2 2 1 1 Part of AAA domain AAA_22 PF13401.1 AIO01418.1 - 0.00054 20.0 0.2 0.0029 17.7 0.0 2.3 3 0 0 3 3 2 1 AAA domain AAA_33 PF13671.1 AIO01418.1 - 0.0012 18.7 0.0 0.018 14.9 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_24 PF13479.1 AIO01418.1 - 0.0016 18.0 0.6 0.0026 17.3 0.0 1.6 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.1 AIO01418.1 - 0.0019 17.6 0.0 0.0053 16.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.7 AIO01418.1 - 0.0044 16.0 0.0 0.0093 15.0 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus IstB_IS21 PF01695.12 AIO01418.1 - 0.0072 15.7 0.0 0.014 14.8 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein Zeta_toxin PF06414.7 AIO01418.1 - 0.013 14.6 0.0 0.03 13.4 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin Arch_ATPase PF01637.13 AIO01418.1 - 0.015 15.0 0.0 0.029 14.0 0.0 1.5 1 0 0 1 1 1 0 Archaeal ATPase KaiC PF06745.8 AIO01418.1 - 0.016 14.3 0.0 0.088 11.9 0.0 2.1 2 0 0 2 2 2 0 KaiC AAA_30 PF13604.1 AIO01418.1 - 0.02 14.5 1.8 0.16 11.5 0.0 2.6 3 0 0 3 3 3 0 AAA domain AAA_18 PF13238.1 AIO01418.1 - 0.025 14.9 0.0 0.054 13.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain SnAC PF14619.1 AIO01418.1 - 0.029 14.5 0.2 16 5.7 0.0 2.7 2 0 0 2 2 2 0 Snf2-ATP coupling, chromatin remodelling complex Mg_chelatase PF01078.16 AIO01418.1 - 0.029 13.5 0.0 0.076 12.1 0.0 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_11 PF13086.1 AIO01418.1 - 0.039 13.5 0.4 0.084 12.4 0.3 1.6 1 1 0 1 1 1 0 AAA domain AAA_28 PF13521.1 AIO01418.1 - 0.043 13.7 0.0 0.11 12.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.1 AIO01418.1 - 0.047 13.5 0.0 0.13 12.2 0.0 1.7 2 0 0 2 2 1 0 AAA domain DUF815 PF05673.8 AIO01418.1 - 0.058 12.3 0.0 0.13 11.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF815) RNA_helicase PF00910.17 AIO01418.1 - 0.076 13.1 0.0 0.25 11.5 0.0 1.9 2 0 0 2 2 1 0 RNA helicase AAA_21 PF13304.1 AIO01418.1 - 0.11 12.4 0.0 0.21 11.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain PhoH PF02562.11 AIO01418.1 - 0.11 11.6 0.0 0.22 10.7 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein PPR_2 PF13041.1 AIO01419.1 - 7.6e-05 22.6 0.2 0.00079 19.3 0.1 2.4 2 0 0 2 2 2 1 PPR repeat family PPR PF01535.15 AIO01419.1 - 0.0011 18.8 0.2 2 8.5 0.0 3.6 3 0 0 3 3 3 1 PPR repeat PPR_3 PF13812.1 AIO01419.1 - 0.006 16.7 0.1 0.062 13.6 0.0 2.9 3 0 0 3 3 3 1 Pentatricopeptide repeat domain TPR_19 PF14559.1 AIO01419.1 - 0.024 14.9 0.0 0.14 12.5 0.0 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat GcrA PF07750.6 AIO01420.1 - 0.0026 17.9 0.8 0.012 15.8 0.0 2.1 2 0 0 2 2 2 1 GcrA cell cycle regulator UIM PF02809.15 AIO01420.1 - 0.019 14.4 0.2 0.052 13.1 0.1 1.8 1 0 0 1 1 1 0 Ubiquitin interaction motif F-box PF00646.28 AIO01420.1 - 0.028 14.0 0.4 0.028 14.0 0.3 1.8 2 0 0 2 2 2 0 F-box domain WD40 PF00400.27 AIO01421.1 - 7e-12 44.7 8.6 1.6e-07 30.8 0.0 4.8 5 0 0 5 5 5 2 WD domain, G-beta repeat PQQ_3 PF13570.1 AIO01421.1 - 0.0043 17.2 1.5 2.1 8.7 0.0 3.8 2 1 1 3 3 3 1 PQQ-like domain Atg14 PF10186.4 AIO01421.1 - 0.044 12.7 0.3 0.083 11.8 0.2 1.4 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 PQQ_2 PF13360.1 AIO01421.1 - 0.34 10.3 6.0 0.81 9.0 1.0 2.8 1 1 1 2 2 2 0 PQQ-like domain zf-C4H2 PF10146.4 AIO01421.1 - 7.1 6.5 6.1 0.26 11.2 0.1 1.7 2 0 0 2 2 2 0 Zinc finger-containing protein WD40 PF00400.27 AIO01422.1 - 4.6e-13 48.4 9.8 6.2e-05 22.7 0.9 5.1 4 0 0 4 4 4 4 WD domain, G-beta repeat COG2 PF06148.6 AIO01422.1 - 0.092 12.6 1.5 0.12 12.2 0.2 1.6 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Matrilin_ccoil PF10393.4 AIO01422.1 - 0.65 9.4 3.3 14 5.1 0.2 2.3 2 0 0 2 2 2 0 Trimeric coiled-coil oligomerisation domain of matrilin PQQ_3 PF13570.1 AIO01422.1 - 7.4 6.9 9.0 40 4.6 0.1 5.2 5 2 0 5 5 5 0 PQQ-like domain GAS2 PF02187.12 AIO01424.1 - 0.015 15.0 0.0 0.032 13.9 0.0 1.5 1 0 0 1 1 1 0 Growth-Arrest-Specific Protein 2 Domain Thioredoxin PF00085.15 AIO01427.1 - 1.1e-09 37.8 0.2 1.9e-09 37.1 0.2 1.3 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.1 AIO01427.1 - 0.0024 17.9 1.0 0.017 15.2 0.0 2.2 2 0 0 2 2 2 1 Thioredoxin-like Thioredoxin_7 PF13899.1 AIO01427.1 - 0.0058 16.6 0.1 0.014 15.3 0.0 1.6 2 0 0 2 2 2 1 Thioredoxin-like AhpC-TSA PF00578.16 AIO01427.1 - 0.006 16.2 0.1 0.0088 15.7 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_2 PF13098.1 AIO01427.1 - 0.05 13.8 1.7 0.17 12.1 1.2 2.1 1 1 0 1 1 1 0 Thioredoxin-like domain DUF965 PF06135.7 AIO01427.1 - 0.082 12.9 0.0 0.14 12.2 0.0 1.4 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF965) Ribosomal_L29 PF00831.18 AIO01427.1 - 0.2 11.3 2.3 11 5.8 0.1 2.5 2 0 0 2 2 2 0 Ribosomal L29 protein MFS_1 PF07690.11 AIO01428.1 - 1.7e-21 76.3 54.1 1.2e-15 57.0 23.4 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Nuc_H_symport PF03825.11 AIO01428.1 - 1.1e-08 34.2 28.2 1.7e-08 33.6 19.5 1.3 1 0 0 1 1 1 1 Nucleoside H+ symporter LacY_symp PF01306.14 AIO01428.1 - 0.00015 20.4 23.9 0.00059 18.4 16.6 1.9 1 1 0 1 1 1 1 LacY proton/sugar symporter MFS_1_like PF12832.2 AIO01428.1 - 0.00041 20.0 1.0 0.0026 17.5 0.1 2.7 2 0 0 2 2 2 1 MFS_1 like family ABC1 PF03109.11 AIO01429.1 - 2.4e-29 101.6 0.0 5e-29 100.7 0.0 1.6 1 0 0 1 1 1 1 ABC1 family RIO1 PF01163.17 AIO01429.1 - 0.0007 19.0 0.0 0.0016 17.8 0.0 1.6 1 0 0 1 1 1 1 RIO1 family WaaY PF06176.6 AIO01429.1 - 0.015 14.5 0.0 0.028 13.6 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) Cwf_Cwc_15 PF04889.7 AIO01430.1 - 0.0015 18.2 14.2 0.0027 17.4 9.4 1.7 1 1 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein HrpA_pilin PF09589.5 AIO01430.1 - 0.0031 17.9 8.0 0.28 11.6 5.6 2.2 1 1 0 1 1 1 1 HrpA pilus formation protein Chibby PF14645.1 AIO01430.1 - 0.11 12.3 4.7 0.3 10.9 0.2 2.3 1 1 1 2 2 2 0 Chibby family SOBP PF15279.1 AIO01430.1 - 2.1 8.6 5.1 2.8 8.2 3.6 1.2 1 0 0 1 1 1 0 Sine oculis-binding protein DUF4551 PF15087.1 AIO01430.1 - 8.6 4.5 11.5 10 4.3 8.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Aminotran_1_2 PF00155.16 AIO01432.1 - 4.7e-51 173.8 0.0 5.3e-51 173.6 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.15 AIO01432.1 - 8.2e-07 27.6 0.2 1.2e-06 27.1 0.1 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.12 AIO01432.1 - 2.3e-05 23.6 0.0 3.3e-05 23.1 0.0 1.1 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.14 AIO01432.1 - 2.7e-05 23.0 0.1 5.6e-05 22.0 0.1 1.4 1 1 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.16 AIO01432.1 - 0.0069 15.5 0.0 0.011 14.9 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase SNARE PF05739.14 AIO01433.1 - 4.5e-17 61.4 3.2 4.5e-17 61.4 2.2 3.0 3 0 0 3 3 3 1 SNARE domain Syntaxin PF00804.20 AIO01433.1 - 6.5e-05 23.0 2.4 6.5e-05 23.0 1.7 2.3 2 0 0 2 2 2 1 Syntaxin Syntaxin_2 PF14523.1 AIO01433.1 - 0.0073 16.3 2.5 0.0073 16.3 1.7 2.3 2 0 0 2 2 2 1 Syntaxin-like protein MCPsignal PF00015.16 AIO01433.1 - 0.24 10.9 7.5 0.037 13.5 1.6 1.9 1 1 1 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain UPF0113 PF03657.8 AIO01434.1 - 0.0044 16.6 0.1 0.013 15.1 0.1 1.8 1 1 0 1 1 1 1 Uncharacterised protein family (UPF0113) Complex1_LYR_1 PF13232.1 AIO01435.1 - 3.1e-06 27.2 0.5 5.2e-06 26.5 0.3 1.3 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.10 AIO01435.1 - 6.3e-06 25.9 0.3 9.6e-06 25.3 0.2 1.3 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Arch_ATPase PF01637.13 AIO01436.1 - 0.26 10.9 0.0 0.39 10.3 0.0 1.2 1 0 0 1 1 1 0 Archaeal ATPase Pkinase PF00069.20 AIO01438.1 - 3.3e-65 219.8 0.0 5.2e-65 219.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AIO01438.1 - 1.4e-31 109.5 0.0 1.8e-31 109.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 AIO01438.1 - 2.3e-06 26.8 0.2 4.1e-06 26.0 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 AIO01438.1 - 6e-05 22.1 0.0 0.0003 19.8 0.0 1.8 1 1 1 2 2 2 1 Kinase-like MRP-L28 PF09812.4 AIO01439.1 - 0.00056 19.7 0.1 0.001 18.8 0.1 1.4 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L28 Hist_deacetyl PF00850.14 AIO01439.1 - 0.026 13.8 0.0 0.035 13.4 0.0 1.2 1 0 0 1 1 1 0 Histone deacetylase domain Pkinase PF00069.20 AIO01440.1 - 2.5e-49 167.7 0.0 1.4e-26 93.1 0.0 3.3 3 0 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.12 AIO01440.1 - 2.5e-28 98.8 0.3 1.4e-19 70.2 0.0 3.1 3 0 0 3 3 3 2 Protein tyrosine kinase FHA PF00498.21 AIO01440.1 - 2.3e-11 43.6 0.0 0.00018 21.5 0.0 3.2 3 0 0 3 3 3 2 FHA domain Kinase-like PF14531.1 AIO01440.1 - 1.6e-06 27.3 0.2 8.3e-05 21.6 0.1 2.2 2 0 0 2 2 2 1 Kinase-like RIO1 PF01163.17 AIO01440.1 - 0.00071 18.9 0.0 0.0013 18.0 0.0 1.3 1 0 0 1 1 1 1 RIO1 family APH PF01636.18 AIO01440.1 - 0.0074 16.0 0.0 0.053 13.2 0.0 2.3 1 1 1 2 2 2 1 Phosphotransferase enzyme family WD40 PF00400.27 AIO01441.1 - 3e-17 61.7 22.0 2.5e-05 23.9 0.1 7.3 7 0 0 7 7 7 4 WD domain, G-beta repeat Nup160 PF11715.3 AIO01441.1 - 4.2e-05 21.8 4.2 0.056 11.5 0.2 3.5 2 1 2 4 4 4 2 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 AIO01441.1 - 0.012 14.3 0.3 0.17 10.5 0.2 2.2 1 1 0 1 1 1 0 Nup133 N terminal like ATG16 PF08614.6 AIO01441.1 - 0.026 14.3 26.4 0.045 13.5 16.0 2.3 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) FUSC PF04632.7 AIO01441.1 - 0.032 12.6 13.0 0.059 11.8 9.0 1.4 1 0 0 1 1 1 0 Fusaric acid resistance protein family LPP PF04728.8 AIO01441.1 - 0.045 13.5 2.6 0.22 11.3 1.8 2.2 1 1 0 1 1 1 0 Lipoprotein leucine-zipper AAA_13 PF13166.1 AIO01441.1 - 0.062 11.7 12.9 0.054 11.9 7.8 1.5 1 1 0 1 1 1 0 AAA domain Rab5-bind PF09311.6 AIO01441.1 - 0.75 9.6 27.8 2.8 7.8 19.0 2.0 1 1 0 1 1 1 0 Rabaptin-like protein DUF972 PF06156.8 AIO01441.1 - 1.1 9.6 18.8 1.5 9.2 3.1 3.2 1 1 3 4 4 4 0 Protein of unknown function (DUF972) Cep57_MT_bd PF06657.8 AIO01441.1 - 2 8.4 19.1 0.078 12.9 3.5 3.0 2 1 0 3 3 3 0 Centrosome microtubule-binding domain of Cep57 Tox-ODYAM1 PF15642.1 AIO01441.1 - 2.1 6.8 10.8 1.7 7.2 6.4 1.5 1 1 0 1 1 1 0 Toxin in Odyssella and Amoebophilus Scaffolding_pro PF11418.3 AIO01441.1 - 2.3 8.5 10.8 0.12 12.7 1.8 2.4 1 1 1 2 2 2 0 Phi29 scaffolding protein TMF_TATA_bd PF12325.3 AIO01441.1 - 2.8 7.6 28.6 0.062 13.0 4.5 2.8 1 1 2 3 3 3 0 TATA element modulatory factor 1 TATA binding Tropomyosin_1 PF12718.2 AIO01441.1 - 7.7 6.3 26.1 0.19 11.5 8.2 2.2 1 1 1 2 2 2 0 Tropomyosin like Aa_trans PF01490.13 AIO01442.1 - 1.3e-53 181.9 22.5 1.5e-53 181.7 15.6 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.8 AIO01442.1 - 7.8e-08 31.5 13.2 7.8e-08 31.5 9.1 2.9 2 1 0 2 2 2 1 Tryptophan/tyrosine permease family ETRAMP PF09716.5 AIO01442.1 - 1.1 9.2 6.2 18 5.3 0.6 3.6 2 2 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) RRM_1 PF00076.17 AIO01444.1 - 5.5e-08 32.3 0.0 4.8e-05 22.9 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 AIO01444.1 - 0.00062 19.6 0.1 0.0021 17.9 0.0 1.9 1 1 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 AIO01444.1 - 0.01 15.6 0.3 0.08 12.8 0.0 2.6 3 1 0 3 3 3 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 AIO01445.1 - 4.4e-12 45.4 0.1 2.4e-09 36.7 0.0 2.3 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 AIO01445.1 - 4.2e-07 29.7 0.0 4.7e-06 26.3 0.0 2.1 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 AIO01445.1 - 5.1e-07 29.5 0.1 7.5e-06 25.8 0.0 2.2 1 1 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 AIO01446.1 - 3e-09 36.7 0.0 1.1e-08 34.9 0.0 1.9 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 AIO01446.1 - 3.1e-09 36.3 0.0 8.9e-09 34.8 0.0 1.8 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 AIO01446.1 - 2.8e-07 30.2 0.0 6.1e-07 29.1 0.0 1.6 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Lipase_3 PF01764.20 AIO01447.1 - 9.2e-39 132.2 0.0 1.3e-38 131.7 0.0 1.2 1 0 0 1 1 1 1 Lipase (class 3) DUF2974 PF11187.3 AIO01447.1 - 0.0001 21.7 0.1 0.0054 16.1 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF2974) Abhydrolase_6 PF12697.2 AIO01447.1 - 0.00043 20.2 0.0 0.00071 19.5 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.15 AIO01447.1 - 0.0036 16.7 0.0 0.0055 16.1 0.0 1.2 1 0 0 1 1 1 1 Putative esterase Abhydrolase_5 PF12695.2 AIO01447.1 - 0.0075 16.0 0.0 0.011 15.4 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 AIO01447.1 - 0.0091 15.6 0.0 0.015 14.9 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_3 PF07859.8 AIO01447.1 - 0.044 13.3 0.0 0.073 12.6 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold Thioesterase PF00975.15 AIO01447.1 - 0.061 13.5 0.0 0.097 12.8 0.0 1.2 1 0 0 1 1 1 0 Thioesterase domain DUF676 PF05057.9 AIO01447.1 - 0.13 11.4 0.0 0.21 10.8 0.0 1.2 1 0 0 1 1 1 0 Putative serine esterase (DUF676) RRM_1 PF00076.17 AIO01448.1 - 1.5e-16 59.7 0.1 2.2e-16 59.2 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 AIO01448.1 - 1.5e-11 44.0 0.1 2.1e-11 43.6 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 AIO01448.1 - 0.0077 16.0 0.0 0.011 15.5 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TPR_7 PF13176.1 AIO01449.1 - 0.00033 20.2 0.9 8.8 6.4 0.0 4.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.1 AIO01449.1 - 0.0021 17.6 16.2 1.8 8.2 0.8 5.2 4 0 0 4 4 4 3 TPR repeat TPR_12 PF13424.1 AIO01449.1 - 0.0062 16.4 1.6 0.0062 16.4 1.1 4.9 4 1 0 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.23 AIO01449.1 - 0.015 14.9 8.9 1.6 8.4 0.1 5.4 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_2 PF07719.12 AIO01449.1 - 0.034 14.0 19.0 0.4 10.7 0.1 6.8 8 0 0 8 8 8 0 Tetratricopeptide repeat TPR_14 PF13428.1 AIO01449.1 - 1.2 9.9 20.0 19 6.2 0.1 7.5 7 1 1 8 8 8 0 Tetratricopeptide repeat ubiquitin PF00240.18 AIO01450.1 - 0.057 12.8 0.1 6.3 6.2 0.1 2.6 2 1 0 2 2 2 0 Ubiquitin family YukD PF08817.5 AIO01450.1 - 0.061 13.8 0.1 0.77 10.3 0.0 2.7 2 0 0 2 2 2 0 WXG100 protein secretion system (Wss), protein YukD TPR_14 PF13428.1 AIO01451.1 - 0.0014 19.0 7.5 0.027 15.0 0.1 4.8 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_16 PF13432.1 AIO01451.1 - 0.012 16.2 3.6 0.023 15.3 0.3 3.2 4 0 0 4 4 4 0 Tetratricopeptide repeat Apc3 PF12895.2 AIO01451.1 - 0.032 14.3 0.0 10 6.3 0.0 3.1 2 1 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.1 AIO01451.1 - 0.11 13.0 1.9 0.45 11.0 0.0 3.1 4 0 0 4 4 4 0 Tetratricopeptide repeat PRA1 PF03208.14 AIO01452.1 - 1.8e-21 76.1 1.4 1.8e-21 76.1 1.0 1.3 2 0 0 2 2 2 1 PRA1 family protein UbiA PF01040.13 AIO01452.1 - 0.021 14.0 1.8 0.031 13.4 1.2 1.2 1 0 0 1 1 1 0 UbiA prenyltransferase family DPM2 PF07297.7 AIO01452.1 - 0.17 12.1 0.4 0.17 12.1 0.3 2.3 2 1 0 2 2 2 0 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) TcpE PF12648.2 AIO01452.1 - 0.49 10.5 8.7 1.8 8.7 1.0 2.4 1 1 1 2 2 2 0 TcpE family PRA1 PF03208.14 AIO01453.1 - 3.6e-28 97.8 7.4 4.9e-28 97.4 5.1 1.1 1 0 0 1 1 1 1 PRA1 family protein zf-DHHC PF01529.15 AIO01453.1 - 2.2 7.6 4.9 3.8 6.8 3.4 1.3 1 0 0 1 1 1 0 DHHC palmitoyltransferase GST_C PF00043.20 AIO01454.1 - 1.4e-13 50.5 0.0 2.3e-13 49.9 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 AIO01454.1 - 8.9e-10 38.6 0.0 2e-09 37.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 AIO01454.1 - 8.2e-08 32.0 0.0 1.4e-07 31.2 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 AIO01454.1 - 9.1e-07 29.2 0.0 2.7e-06 27.7 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 AIO01454.1 - 0.0013 18.8 0.0 0.0025 18.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain MetRS-N PF09635.5 AIO01454.1 - 0.088 13.1 0.0 0.22 11.9 0.0 1.6 1 0 0 1 1 1 0 MetRS-N binding domain FlgN PF05130.7 AIO01455.1 - 0.031 14.5 0.5 2.2 8.4 0.1 2.5 2 0 0 2 2 2 0 FlgN protein ABC_tran_2 PF12848.2 AIO01455.1 - 0.12 12.2 0.0 0.23 11.2 0.0 1.4 1 0 0 1 1 1 0 ABC transporter GP41 PF00517.12 AIO01455.1 - 0.13 11.8 0.6 0.23 10.9 0.4 1.4 1 0 0 1 1 1 0 Retroviral envelope protein TauE PF01925.14 AIO01456.1 - 2e-13 50.3 20.4 5.5e-07 29.2 6.4 2.2 2 0 0 2 2 2 2 Sulfite exporter TauE/SafE DUF2681 PF10883.3 AIO01456.1 - 0.0044 17.1 0.4 0.086 13.0 0.2 2.8 2 0 0 2 2 2 1 Protein of unknown function (DUF2681) DivIC PF04977.10 AIO01456.1 - 0.0068 15.8 0.1 0.019 14.4 0.1 1.7 1 0 0 1 1 1 1 Septum formation initiator WBP-1 PF11669.3 AIO01456.1 - 0.027 14.5 3.8 6.1 6.9 0.4 3.0 3 0 0 3 3 3 0 WW domain-binding protein 1 DUF2244 PF10003.4 AIO01456.1 - 0.037 13.3 0.2 0.037 13.3 0.2 3.1 3 1 1 4 4 4 0 Integral membrane protein (DUF2244) MSC PF09402.5 AIO01456.1 - 0.041 12.5 0.7 0.58 8.8 0.1 2.1 2 0 0 2 2 2 0 Man1-Src1p-C-terminal domain CcmD PF04995.9 AIO01456.1 - 0.15 11.8 0.4 26 4.6 0.1 2.7 2 0 0 2 2 2 0 Heme exporter protein D (CcmD) DUF1049 PF06305.6 AIO01456.1 - 0.49 9.9 4.2 0.42 10.1 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1049) Ribul_P_3_epim PF00834.14 AIO01457.1 - 5.4e-58 195.4 0.0 6.5e-58 195.1 0.0 1.0 1 0 0 1 1 1 1 Ribulose-phosphate 3 epimerase family OMPdecase PF00215.19 AIO01457.1 - 0.0026 17.1 0.3 0.0076 15.6 0.2 1.8 2 1 0 2 2 2 1 Orotidine 5'-phosphate decarboxylase / HUMPS family PcrB PF01884.12 AIO01457.1 - 0.092 11.9 0.1 0.21 10.8 0.1 1.6 1 1 0 1 1 1 0 PcrB family IGFL PF14653.1 AIO01458.1 - 0.2 11.7 1.7 0.42 10.6 1.2 1.5 1 0 0 1 1 1 0 Insulin growth factor-like family adh_short PF00106.20 AIO01460.1 - 2.9e-21 76.1 0.0 3.9e-21 75.6 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 AIO01460.1 - 7.8e-11 42.1 0.0 1.1e-10 41.7 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 AIO01460.1 - 9.9e-10 38.3 0.0 1.5e-09 37.7 0.0 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 AIO01460.1 - 0.00066 19.7 0.0 0.029 14.3 0.0 2.1 2 0 0 2 2 2 1 NADH(P)-binding Eno-Rase_NADH_b PF12242.3 AIO01460.1 - 0.0045 16.7 0.1 0.011 15.5 0.0 1.6 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase 3HCDH_N PF02737.13 AIO01460.1 - 0.015 14.9 0.1 0.032 13.8 0.0 1.6 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Ribosomal_L17 PF01196.14 AIO01460.1 - 0.05 14.1 0.2 0.35 11.4 0.0 2.3 2 1 0 3 3 3 0 Ribosomal protein L17 Epimerase PF01370.16 AIO01460.1 - 0.055 12.8 0.1 0.075 12.4 0.1 1.5 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family DFP PF04127.10 AIO01460.1 - 0.074 12.6 0.2 0.98 9.0 0.0 2.1 2 0 0 2 2 2 0 DNA / pantothenate metabolism flavoprotein HHH_5 PF14520.1 AIO01460.1 - 0.1 12.7 0.0 0.21 11.7 0.0 1.5 1 0 0 1 1 1 0 Helix-hairpin-helix domain Peptidase_M20 PF01546.23 AIO01462.1 - 4.5e-20 71.9 0.0 7.4e-20 71.2 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 AIO01462.1 - 3.2e-11 42.9 0.0 5.7e-11 42.1 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.12 AIO01462.1 - 0.046 13.4 0.0 0.069 12.8 0.0 1.3 1 0 0 1 1 1 0 Peptidase family M28 HEAT PF02985.17 AIO01463.1 - 2.9e-12 45.5 9.2 0.76 10.0 0.0 8.9 9 0 0 9 9 9 5 HEAT repeat HEAT_2 PF13646.1 AIO01463.1 - 3.2e-09 36.9 0.3 0.0098 16.1 0.0 5.9 4 2 2 6 6 6 3 HEAT repeats Vac14_Fab1_bd PF12755.2 AIO01463.1 - 0.011 16.1 2.1 0.81 10.1 0.0 4.2 5 0 0 5 5 5 0 Vacuolar 14 Fab1-binding region CLASP_N PF12348.3 AIO01463.1 - 0.056 12.7 4.0 0.35 10.1 0.6 3.7 4 1 0 4 4 4 0 CLASP N terminal Cnd1 PF12717.2 AIO01463.1 - 0.064 13.1 5.4 11 5.8 0.2 4.2 4 0 0 4 4 4 0 non-SMC mitotic condensation complex subunit 1 Pro_isomerase PF00160.16 AIO01464.1 - 6.8e-45 153.0 0.1 7.9e-45 152.8 0.1 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD YfkB PF08756.5 AIO01465.1 - 0.1 12.2 0.0 0.13 11.7 0.0 1.3 1 0 0 1 1 1 0 YfkB-like domain PIGA PF08288.7 AIO01468.1 - 5.5e-38 129.2 0.0 1.1e-37 128.2 0.0 1.5 1 0 0 1 1 1 1 PIGA (GPI anchor biosynthesis) Glycos_transf_1 PF00534.15 AIO01468.1 - 2.2e-28 98.7 0.0 3.5e-28 98.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.1 AIO01468.1 - 1.6e-16 60.5 0.0 3.9e-16 59.2 0.0 1.7 1 1 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.1 AIO01468.1 - 4.8e-15 56.0 0.0 1e-14 54.9 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_trans_1_4 PF13692.1 AIO01468.1 - 8.8e-13 48.5 0.0 1.4e-12 47.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_2 PF13477.1 AIO01468.1 - 0.01 15.6 0.0 0.035 13.9 0.0 1.8 2 0 0 2 2 2 0 Glycosyl transferase 4-like Glyco_trans_1_2 PF13524.1 AIO01468.1 - 0.01 16.0 0.0 0.029 14.6 0.0 1.7 1 0 0 1 1 1 0 Glycosyl transferases group 1 Glyco_trans_2_3 PF13632.1 AIO01468.1 - 0.66 9.6 3.8 0.2 11.3 0.3 1.8 2 0 0 2 2 2 0 Glycosyl transferase family group 2 ThiI PF02568.9 AIO01469.1 - 1.5e-46 158.4 0.1 2.4e-46 157.6 0.1 1.3 1 0 0 1 1 1 1 Thiamine biosynthesis protein (ThiI) Aminotran_5 PF00266.14 AIO01469.1 - 1.6e-27 96.2 0.5 2.1e-13 49.7 0.0 2.2 1 1 0 2 2 2 2 Aminotransferase class-V tRNA_Me_trans PF03054.11 AIO01469.1 - 0.00013 20.6 0.0 0.00025 19.7 0.0 1.4 1 0 0 1 1 1 1 tRNA methyl transferase QueC PF06508.8 AIO01469.1 - 0.0021 17.3 0.5 0.041 13.1 0.0 2.6 3 0 0 3 3 3 1 Queuosine biosynthesis protein QueC DNA_pol_B PF00136.16 AIO01470.1 - 4.1e-140 467.6 0.0 5.9e-140 467.1 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.14 AIO01470.1 - 3.1e-73 246.4 0.0 5.5e-73 245.6 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.1 AIO01470.1 - 2.2e-22 78.8 9.4 5.3e-22 77.6 6.5 1.7 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta RNase_H_2 PF13482.1 AIO01470.1 - 0.045 13.5 0.2 0.22 11.3 0.2 2.1 1 1 0 1 1 1 0 RNase_H superfamily zf-RING-like PF08746.6 AIO01470.1 - 0.46 10.5 9.0 6.8 6.7 1.4 3.1 2 0 0 2 2 2 0 RING-like domain zinc-ribbons_6 PF07191.7 AIO01470.1 - 1 9.2 8.5 2.5 7.9 0.4 3.1 3 0 0 3 3 3 0 zinc-ribbons SNF2_N PF00176.18 AIO01471.1 - 2.2e-78 263.1 0.3 1.8e-77 260.0 0.0 2.2 2 0 0 2 2 2 1 SNF2 family N-terminal domain SLIDE PF09111.5 AIO01471.1 - 6.7e-22 77.4 0.9 1.7e-21 76.0 0.6 1.8 1 0 0 1 1 1 1 SLIDE Helicase_C PF00271.26 AIO01471.1 - 2.2e-16 59.4 0.0 8.4e-16 57.6 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 AIO01471.1 - 1.3e-05 25.1 0.0 0.00014 21.7 0.0 2.6 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.24 AIO01471.1 - 4.8e-05 22.9 0.0 0.00013 21.5 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase HAND PF09110.6 AIO01471.1 - 0.0019 18.5 2.1 0.0065 16.8 1.4 1.9 1 0 0 1 1 1 1 HAND HDA2-3 PF11496.3 AIO01471.1 - 0.0047 15.7 0.0 0.012 14.4 0.0 1.6 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 Pkinase PF00069.20 AIO01472.1 - 3e-66 223.2 0.0 4.7e-66 222.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AIO01472.1 - 2.2e-40 138.3 0.1 3.6e-40 137.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase EF-hand_7 PF13499.1 AIO01472.1 - 3.7e-12 46.1 0.7 1e-05 25.5 0.1 3.0 3 0 0 3 3 2 2 EF-hand domain pair EF-hand_1 PF00036.27 AIO01472.1 - 5.6e-12 44.0 0.6 0.039 13.2 0.1 4.7 5 0 0 5 5 5 3 EF hand EF-hand_8 PF13833.1 AIO01472.1 - 1.8e-11 43.4 4.0 0.00016 21.1 0.2 3.8 3 1 1 4 4 4 3 EF-hand domain pair EF-hand_6 PF13405.1 AIO01472.1 - 7.5e-10 37.8 0.6 0.018 14.8 0.0 5.0 3 1 2 5 5 5 2 EF-hand domain Kinase-like PF14531.1 AIO01472.1 - 4.8e-09 35.5 0.0 2.4e-08 33.3 0.0 1.9 1 1 1 2 2 2 1 Kinase-like RIO1 PF01163.17 AIO01472.1 - 1.4e-05 24.4 1.7 3.2e-05 23.3 1.2 1.5 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.9 AIO01472.1 - 0.015 14.3 0.1 0.03 13.3 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family EF-hand_5 PF13202.1 AIO01472.1 - 0.018 14.3 0.1 24 4.4 0.0 3.7 3 0 0 3 3 3 0 EF hand YrbL-PhoP_reg PF10707.4 AIO01472.1 - 0.045 13.0 0.1 0.092 12.0 0.1 1.4 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL APH PF01636.18 AIO01472.1 - 0.071 12.8 0.0 0.19 11.4 0.0 1.8 2 0 0 2 2 2 0 Phosphotransferase enzyme family DUF2414 PF10309.4 AIO01472.1 - 0.1 12.3 0.1 0.8 9.4 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2414) Crystallin PF00525.13 AIO01472.1 - 0.13 12.5 0.1 0.29 11.3 0.0 1.5 1 0 0 1 1 1 0 Alpha crystallin A chain, N terminal TPR_12 PF13424.1 AIO01473.1 - 7.3e-18 64.2 9.3 2.9e-09 36.7 0.2 3.6 1 1 2 4 4 4 3 Tetratricopeptide repeat TPR_11 PF13414.1 AIO01473.1 - 2.9e-12 46.0 6.0 0.0001 21.8 0.3 3.6 3 1 0 3 3 3 3 TPR repeat TPR_1 PF00515.23 AIO01473.1 - 3.5e-12 45.3 8.6 0.029 13.9 0.2 5.4 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_2 PF07719.12 AIO01473.1 - 2.5e-07 30.0 13.3 0.2 11.6 0.3 5.6 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_8 PF13181.1 AIO01473.1 - 2.2e-05 23.9 2.9 1.7 8.6 0.1 5.0 5 0 0 5 5 5 1 Tetratricopeptide repeat Apc5 PF12862.2 AIO01473.1 - 3.8e-05 23.4 4.3 0.12 12.2 0.1 3.1 1 1 1 3 3 3 2 Anaphase-promoting complex subunit 5 TPR_21 PF09976.4 AIO01473.1 - 0.0079 16.1 0.1 0.027 14.3 0.1 1.9 1 1 0 1 1 1 1 Tetratricopeptide repeat TPR_7 PF13176.1 AIO01473.1 - 0.011 15.5 6.9 6.5 6.8 0.0 5.0 6 0 0 6 6 6 0 Tetratricopeptide repeat RPN7 PF10602.4 AIO01473.1 - 0.047 13.0 3.2 4.1 6.7 0.0 3.4 1 1 4 5 5 5 0 26S proteasome subunit RPN7 TPR_14 PF13428.1 AIO01473.1 - 0.079 13.6 3.3 16 6.4 0.3 4.4 4 1 1 5 5 5 0 Tetratricopeptide repeat TPR_9 PF13371.1 AIO01473.1 - 0.17 11.7 5.4 2.7 7.9 0.0 3.6 2 1 1 3 3 3 0 Tetratricopeptide repeat Apc3 PF12895.2 AIO01473.1 - 0.72 10.0 6.8 14 5.9 1.8 3.1 2 1 1 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_10 PF13374.1 AIO01473.1 - 1 9.3 4.5 18 5.4 0.0 4.1 4 1 0 4 4 4 0 Tetratricopeptide repeat MIF PF01187.13 AIO01475.1 - 4.7e-05 23.4 0.0 4.9e-05 23.3 0.0 1.0 1 0 0 1 1 1 1 Macrophage migration inhibitory factor (MIF) OTT_1508_deam PF14441.1 AIO01476.1 - 2.3e-12 46.9 0.0 3.4e-12 46.3 0.0 1.2 1 0 0 1 1 1 1 OTT_1508-like deaminase dCMP_cyt_deam_1 PF00383.17 AIO01476.1 - 0.089 12.4 0.1 0.14 11.7 0.0 1.3 1 0 0 1 1 1 0 Cytidine and deoxycytidylate deaminase zinc-binding region XOO_2897-deam PF14440.1 AIO01476.1 - 0.1 12.2 0.0 0.18 11.4 0.0 1.4 1 0 0 1 1 1 0 Xanthomonas XOO_2897-like deaminase LisH PF08513.6 AIO01477.1 - 0.021 14.5 0.1 0.061 13.1 0.1 1.9 1 0 0 1 1 1 0 LisH DOT1 PF08123.8 AIO01478.1 - 1.9e-15 56.7 0.1 2.7e-15 56.2 0.1 1.1 1 0 0 1 1 1 1 Histone methylation protein DOT1 Methyltransf_26 PF13659.1 AIO01478.1 - 0.0003 20.7 0.0 0.00057 19.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 AIO01478.1 - 0.00037 20.0 0.0 0.0007 19.2 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 AIO01478.1 - 0.00052 20.5 0.0 0.00084 19.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 AIO01478.1 - 0.021 13.8 0.1 0.059 12.4 0.0 1.8 1 1 1 2 2 2 0 Putative methyltransferase Methyltransf_12 PF08242.7 AIO01478.1 - 0.047 14.1 0.0 0.099 13.1 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain DER1 PF04511.10 AIO01479.1 - 5.1e-32 110.9 11.4 5.9e-32 110.7 7.9 1.0 1 0 0 1 1 1 1 Der1-like family Pkinase PF00069.20 AIO01482.1 - 1.6e-52 178.2 0.0 2.2e-52 177.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AIO01482.1 - 9.2e-23 80.6 0.0 1.4e-22 80.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 AIO01482.1 - 0.0021 17.8 0.0 0.0076 16.0 0.0 1.8 1 1 1 2 2 2 1 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.6 AIO01482.1 - 0.025 13.4 0.3 0.069 11.9 0.0 1.7 2 0 0 2 2 2 0 Poxvirus serine/threonine protein kinase Ras PF00071.17 AIO01483.1 - 1.6e-49 167.4 0.0 1.9e-49 167.1 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 AIO01483.1 - 2.6e-16 60.1 0.0 4.3e-16 59.4 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 AIO01483.1 - 6.4e-16 58.0 0.0 7.7e-16 57.8 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 AIO01483.1 - 1.5e-06 27.5 0.0 2.4e-06 26.8 0.0 1.4 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 AIO01483.1 - 9.3e-06 25.5 0.0 1.5e-05 24.9 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.11 AIO01483.1 - 0.00097 18.3 0.1 0.005 16.0 0.1 2.0 2 0 0 2 2 2 1 Protein of unknown function, DUF258 GTP_EFTU PF00009.22 AIO01483.1 - 0.0018 17.7 0.0 0.013 14.9 0.0 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_24 PF13479.1 AIO01483.1 - 0.0021 17.6 0.3 0.0038 16.8 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.1 AIO01483.1 - 0.0063 16.0 2.1 0.021 14.3 0.9 2.2 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_16 PF13191.1 AIO01483.1 - 0.01 15.8 0.6 0.052 13.5 0.1 2.1 2 0 0 2 2 2 0 AAA ATPase domain DAP3 PF10236.4 AIO01483.1 - 0.016 14.1 0.1 0.025 13.5 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 ATP_bind_1 PF03029.12 AIO01483.1 - 0.016 14.7 0.2 0.076 12.5 0.0 1.9 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein MCM PF00493.18 AIO01483.1 - 0.022 13.5 0.0 0.039 12.7 0.0 1.4 1 0 0 1 1 1 0 MCM2/3/5 family AAA_10 PF12846.2 AIO01483.1 - 0.035 13.5 0.7 0.05 13.0 0.5 1.6 1 1 0 1 1 1 0 AAA-like domain ABC_tran PF00005.22 AIO01483.1 - 0.043 14.1 0.2 0.096 12.9 0.0 1.7 2 0 0 2 2 2 0 ABC transporter SRPRB PF09439.5 AIO01483.1 - 0.085 12.0 0.0 0.12 11.5 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_5 PF07728.9 AIO01483.1 - 0.11 12.2 0.1 0.42 10.3 0.0 1.9 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) DUF815 PF05673.8 AIO01483.1 - 0.11 11.3 0.3 0.26 10.1 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF815) DUF4054 PF13262.1 AIO01484.1 - 0.054 13.7 0.7 0.4 10.9 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4054) ABC_membrane_2 PF06472.10 AIO01485.1 - 2.8e-69 233.3 0.6 3.7e-69 232.9 0.4 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 ABC_tran PF00005.22 AIO01485.1 - 3.2e-18 66.3 0.0 6.2e-18 65.4 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 AIO01485.1 - 0.00036 20.5 0.0 0.0022 18.0 0.0 2.0 2 0 0 2 2 2 1 AAA domain SMC_N PF02463.14 AIO01485.1 - 0.0038 16.5 0.0 0.19 10.8 0.0 2.6 3 0 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 AIO01485.1 - 0.013 14.9 0.1 0.037 13.5 0.1 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain NACHT PF05729.7 AIO01485.1 - 0.015 14.9 0.1 0.24 11.0 0.0 2.6 3 0 0 3 3 3 0 NACHT domain DUF3584 PF12128.3 AIO01485.1 - 0.015 12.6 0.5 0.026 11.9 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) FtsK_SpoIIIE PF01580.13 AIO01485.1 - 0.03 13.8 0.0 0.056 12.9 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_22 PF13401.1 AIO01485.1 - 0.035 14.2 0.9 0.91 9.6 0.0 3.2 4 0 0 4 4 4 0 AAA domain Mg_chelatase PF01078.16 AIO01485.1 - 0.059 12.5 0.2 0.18 10.9 0.0 1.8 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_10 PF12846.2 AIO01485.1 - 0.07 12.5 0.1 0.42 10.0 0.1 2.1 2 0 0 2 2 2 0 AAA-like domain DUF87 PF01935.12 AIO01485.1 - 0.071 12.9 0.1 0.14 11.9 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function DUF87 AAA_13 PF13166.1 AIO01485.1 - 0.11 10.9 0.0 0.2 10.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.1 AIO01485.1 - 0.12 12.6 0.0 0.23 11.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.1 AIO01485.1 - 0.15 11.6 0.0 0.32 10.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain NOG1 PF06858.9 AIO01486.1 - 2.4e-28 97.7 0.0 6.2e-28 96.4 0.0 1.8 1 0 0 1 1 1 1 Nucleolar GTP-binding protein 1 (NOG1) NOGCT PF08155.6 AIO01486.1 - 4.1e-23 80.8 6.6 6.9e-23 80.0 3.8 2.0 2 0 0 2 2 2 1 NOGCT (NUC087) domain MMR_HSR1 PF01926.18 AIO01486.1 - 7.3e-17 61.3 0.0 1.6e-16 60.2 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 AIO01486.1 - 7.8e-10 38.2 0.0 1.5e-09 37.3 0.0 1.5 1 0 0 1 1 1 1 Ferrous iron transport protein B Miro PF08477.8 AIO01486.1 - 3.6e-05 24.2 0.0 8.9e-05 22.9 0.0 1.7 1 0 0 1 1 1 1 Miro-like protein PduV-EutP PF10662.4 AIO01486.1 - 0.0042 16.5 0.1 0.01 15.2 0.0 1.7 1 0 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation AIG1 PF04548.11 AIO01486.1 - 0.0061 15.6 0.1 0.019 14.1 0.0 1.8 2 0 0 2 2 2 1 AIG1 family Ras PF00071.17 AIO01486.1 - 0.013 14.8 0.1 0.036 13.4 0.0 1.7 1 1 0 1 1 1 0 Ras family IQ PF00612.22 AIO01487.1 - 0.00028 20.2 0.3 0.00096 18.5 0.2 1.9 1 0 0 1 1 1 1 IQ calmodulin-binding motif Hyccin PF09790.4 AIO01487.1 - 0.015 14.2 0.0 0.022 13.6 0.0 1.2 1 0 0 1 1 1 0 Hyccin FOP_dimer PF09398.5 AIO01489.1 - 1.2e-11 44.4 0.1 2.9e-11 43.2 0.0 1.6 2 0 0 2 2 2 1 FOP N terminal dimerisation domain LisH PF08513.6 AIO01489.1 - 0.0029 17.2 0.1 0.006 16.3 0.1 1.6 1 0 0 1 1 1 1 LisH Snf7 PF03357.16 AIO01490.1 - 5.8e-17 61.6 9.9 5.8e-17 61.6 6.8 2.0 1 1 1 2 2 2 1 Snf7 Ist1 PF03398.9 AIO01490.1 - 0.0016 17.8 2.5 0.009 15.4 1.0 2.0 2 0 0 2 2 2 1 Regulator of Vps4 activity in the MVB pathway LAP2alpha PF11560.3 AIO01490.1 - 0.036 13.2 0.8 0.052 12.7 0.3 1.4 1 1 0 1 1 1 0 Lamina-associated polypeptide 2 alpha DUF1463 PF07316.6 AIO01490.1 - 0.32 10.5 2.0 15 5.1 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1463) CAF1C_H4-bd PF12265.3 AIO01491.1 - 4.5e-18 64.9 0.1 1.2e-17 63.5 0.1 1.7 1 0 0 1 1 1 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex WD40 PF00400.27 AIO01491.1 - 9.9e-07 28.4 11.6 0.014 15.2 0.0 4.7 5 0 0 5 5 5 2 WD domain, G-beta repeat DUF2457 PF10446.4 AIO01491.1 - 0.002 16.9 33.5 0.008 14.9 15.5 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF2457) SDA1 PF05285.7 AIO01491.1 - 0.32 10.2 25.5 0.59 9.3 11.2 2.3 2 0 0 2 2 2 0 SDA1 Utp14 PF04615.8 AIO01491.1 - 0.59 8.2 16.5 0.84 7.7 7.7 2.1 2 0 0 2 2 2 0 Utp14 protein Pho88 PF10032.4 AIO01492.1 - 1.7e-45 154.5 0.0 2e-45 154.3 0.0 1.0 1 0 0 1 1 1 1 Phosphate transport (Pho88) UPF0182 PF03699.8 AIO01492.1 - 0.06 11.2 0.0 0.072 11.0 0.0 1.0 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0182) Intg_mem_TP0381 PF09529.5 AIO01492.1 - 0.98 8.6 7.1 0.22 10.7 2.7 1.5 2 0 0 2 2 2 0 Integral membrane protein (intg_mem_TP0381) Pribosyltran_N PF13793.1 AIO01494.1 - 5.8e-39 132.4 0.2 7e-38 128.9 0.0 2.2 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.1 AIO01494.1 - 4e-22 78.8 0.7 2.5e-21 76.2 0.1 2.1 1 1 1 2 2 2 1 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.22 AIO01494.1 - 1.3e-12 47.5 0.2 2.6e-12 46.5 0.1 1.5 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.1 AIO01494.1 - 0.041 13.0 0.2 0.074 12.2 0.1 1.4 1 0 0 1 1 1 0 Uracil phosphoribosyltransferase HTH_CodY PF08222.6 AIO01494.1 - 0.079 12.3 0.2 0.18 11.1 0.1 1.6 1 0 0 1 1 1 0 CodY helix-turn-helix domain Ribosomal_L37e PF01907.14 AIO01497.1 - 1.5e-26 91.9 8.2 2.5e-26 91.1 5.7 1.4 1 0 0 1 1 1 1 Ribosomal protein L37e DZR PF12773.2 AIO01497.1 - 0.067 13.0 0.7 0.11 12.2 0.5 1.4 1 0 0 1 1 1 0 Double zinc ribbon zinc_ribbon_6 PF14599.1 AIO01497.1 - 0.083 12.6 0.5 0.13 12.0 0.3 1.3 1 0 0 1 1 1 0 Zinc-ribbon Pkinase PF00069.20 AIO01500.1 - 1.1e-59 201.7 0.0 1.6e-59 201.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AIO01500.1 - 2.1e-37 128.5 0.0 2.8e-37 128.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 AIO01500.1 - 4.2e-08 32.5 0.0 5.1e-08 32.2 0.0 1.3 1 0 0 1 1 1 1 Kinase-like PH PF00169.24 AIO01500.1 - 1.3e-05 25.3 0.0 5.5e-05 23.3 0.0 2.0 2 0 0 2 2 2 1 PH domain PH_9 PF15410.1 AIO01500.1 - 0.14 12.3 0.0 5.6 7.1 0.0 2.5 1 1 0 1 1 1 0 Pleckstrin homology domain Skp1 PF01466.14 AIO01501.1 - 0.0026 17.7 0.1 0.0049 16.8 0.0 1.3 1 0 0 1 1 1 1 Skp1 family, dimerisation domain PEN-2 PF10251.4 AIO01502.1 - 2e-06 27.9 4.8 2.8e-06 27.4 3.4 1.4 1 1 0 1 1 1 1 Presenilin enhancer-2 subunit of gamma secretase DUF4231 PF14015.1 AIO01502.1 - 0.013 15.4 0.2 0.02 14.8 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4231) 7tm_2 PF00002.19 AIO01502.1 - 0.02 13.9 2.8 0.023 13.7 2.0 1.1 1 0 0 1 1 1 0 7 transmembrane receptor (Secretin family) FA_desaturase PF00487.19 AIO01502.1 - 0.073 12.4 5.4 0.082 12.3 3.8 1.0 1 0 0 1 1 1 0 Fatty acid desaturase COQ9 PF08511.6 AIO01502.1 - 0.078 12.4 0.1 0.14 11.6 0.1 1.4 1 0 0 1 1 1 0 COQ9 Peptidase_C2 PF00648.16 AIO01503.1 - 3.7e-27 95.0 0.0 6.6e-27 94.2 0.0 1.3 1 0 0 1 1 1 1 Calpain family cysteine protease Calpain_III PF01067.17 AIO01503.1 - 2.3e-13 50.0 0.1 2.7e-06 27.0 0.0 3.4 3 0 0 3 3 3 3 Calpain large subunit, domain III MIT PF04212.13 AIO01503.1 - 9.6e-05 22.1 0.2 0.00022 21.0 0.1 1.6 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain TPR_11 PF13414.1 AIO01503.1 - 0.021 14.4 1.4 0.073 12.7 0.1 2.2 2 0 0 2 2 2 0 TPR repeat TPR_2 PF07719.12 AIO01503.1 - 0.15 12.0 0.2 1.9 8.5 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_1 PF00515.23 AIO01503.1 - 0.2 11.3 0.3 0.75 9.5 0.2 2.0 2 0 0 2 2 2 0 Tetratricopeptide repeat Arm PF00514.18 AIO01505.1 - 0.0067 16.2 1.8 47 4.0 0.1 5.2 5 0 0 5 5 5 3 Armadillo/beta-catenin-like repeat Nup84_Nup100 PF04121.8 AIO01506.1 - 0.00013 19.7 0.2 0.32 8.6 0.0 2.9 3 0 0 3 3 3 2 Nuclear pore protein 84 / 107 Peptidase_M23 PF01551.17 AIO01506.1 - 0.023 14.7 0.0 0.96 9.5 0.0 2.5 2 0 0 2 2 2 0 Peptidase family M23 Pkinase PF00069.20 AIO01509.1 - 1.2e-47 162.3 0.0 7.7e-37 126.8 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 AIO01509.1 - 1.4e-26 93.1 0.1 2.8e-18 65.9 0.1 3.1 2 1 0 2 2 2 2 Protein tyrosine kinase E1-E2_ATPase PF00122.15 AIO01511.1 - 4.2e-48 163.3 1.9 1.3e-47 161.7 0.1 2.3 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.21 AIO01511.1 - 2.4e-35 122.9 1.0 5.8e-35 121.6 0.4 1.9 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HMA PF00403.21 AIO01511.1 - 6.4e-35 119.1 0.3 2e-11 43.8 0.0 3.5 3 0 0 3 3 3 3 Heavy-metal-associated domain HAD PF12710.2 AIO01511.1 - 2.4e-13 50.7 0.0 6.6e-13 49.2 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 AIO01511.1 - 7.3e-06 25.7 0.3 0.00018 21.2 0.1 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase CoA_binding_2 PF13380.1 AIO01511.1 - 0.0092 16.1 0.1 0.053 13.6 0.1 2.3 1 1 0 1 1 1 1 CoA binding domain His_Phos_1 PF00300.17 AIO01512.1 - 5e-24 85.1 0.1 3.3e-22 79.2 0.0 2.3 2 0 0 2 2 2 2 Histidine phosphatase superfamily (branch 1) His_Phos_1 PF00300.17 AIO01513.1 - 5.4e-19 68.8 0.0 1.4e-18 67.4 0.0 1.7 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) zf-HIT PF04438.11 AIO01514.1 - 3.9e-07 29.5 14.6 9.8e-07 28.3 10.1 1.7 1 0 0 1 1 1 1 HIT zinc finger zf-MYND PF01753.13 AIO01514.1 - 0.045 13.6 12.0 0.097 12.5 8.3 1.6 1 0 0 1 1 1 0 MYND finger zf-B_box PF00643.19 AIO01514.1 - 4 7.4 12.0 0.63 9.9 5.2 2.0 2 0 0 2 2 2 0 B-box zinc finger Kinesin PF00225.18 AIO01516.1 - 1.3e-81 273.9 0.0 3.2e-81 272.6 0.0 1.6 1 0 0 1 1 1 1 Kinesin motor domain WD40 PF00400.27 AIO01517.1 - 4e-07 29.6 16.8 0.059 13.2 0.3 6.6 7 0 0 7 7 7 3 WD domain, G-beta repeat DUF3312 PF11768.3 AIO01517.1 - 0.0057 14.9 0.0 0.0092 14.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3312) Dscam_C PF12355.3 AIO01517.1 - 0.035 14.3 0.5 0.22 11.7 0.1 2.2 2 0 0 2 2 2 0 Down syndrome cell adhesion molecule C terminal Dynein_heavy PF03028.10 AIO01517.1 - 0.078 10.9 0.0 0.11 10.5 0.0 1.1 1 0 0 1 1 1 0 Dynein heavy chain and region D6 of dynein motor Acid_PPase PF12689.2 AIO01518.1 - 1.9e-49 167.5 0.0 2.2e-49 167.3 0.0 1.0 1 0 0 1 1 1 1 Acid Phosphatase Hydrolase PF00702.21 AIO01518.1 - 0.016 15.6 0.0 0.018 15.4 0.0 1.4 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase HAD PF12710.2 AIO01518.1 - 0.068 13.3 0.0 0.098 12.8 0.0 1.3 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase NIF PF03031.13 AIO01518.1 - 0.12 12.0 0.0 0.18 11.4 0.0 1.3 1 0 0 1 1 1 0 NLI interacting factor-like phosphatase DUF2798 PF11391.3 AIO01523.1 - 0.55 10.0 5.3 1.2 8.9 1.7 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF2798) DUF1279 PF06916.8 AIO01524.1 - 0.022 15.0 0.1 0.056 13.7 0.1 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1279) Mei5 PF10376.4 AIO01524.1 - 0.17 11.3 3.0 0.24 10.9 2.1 1.1 1 0 0 1 1 1 0 Double-strand recombination repair protein YqfQ PF14181.1 AIO01524.1 - 0.29 11.1 0.1 0.29 11.1 0.1 1.6 2 0 0 2 2 2 0 YqfQ-like protein PaaSYMP PF14738.1 AIO01525.1 - 2.8e-47 160.2 3.2 2.8e-47 160.2 2.2 2.7 2 1 0 2 2 2 1 Solute carrier (proton/amino acid symporter), TRAMD3 or PAT1 PDDEXK_1 PF12705.2 AIO01525.1 - 1.8 7.8 8.7 0.23 10.8 1.9 2.3 2 1 0 2 2 2 0 PD-(D/E)XK nuclease superfamily DUF3761 PF12587.3 AIO01527.1 - 0.11 12.5 0.0 0.23 11.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3761) Baculo_IE-1 PF05290.6 AIO01528.1 - 0.0047 16.6 2.6 0.0077 15.9 1.8 1.2 1 0 0 1 1 1 1 Baculovirus immediate-early protein (IE-0) zf-C3HC4_3 PF13920.1 AIO01528.1 - 0.75 9.5 14.5 1.5 8.5 10.0 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Glyco_hydro_85 PF03644.8 AIO01529.1 - 3.2e-100 335.2 0.0 4.6e-100 334.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 85 Peptidase_C97 PF05903.9 AIO01529.1 - 9.1e-25 87.2 0.0 1.6e-24 86.4 0.0 1.4 1 0 0 1 1 1 1 PPPDE putative peptidase domain PUB PF09409.5 AIO01529.1 - 6.4e-14 51.4 0.0 4.3e-13 48.8 0.0 2.1 1 1 1 2 2 2 1 PUB domain DUF3421 PF11901.3 AIO01529.1 - 9.3e-07 28.6 0.3 0.0043 16.7 0.0 2.8 2 0 0 2 2 2 2 Protein of unknown function (DUF3421) Glyco_hydro_18 PF00704.23 AIO01529.1 - 0.012 15.1 0.0 0.019 14.4 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolases family 18 Tmemb_cc2 PF10267.4 AIO01530.1 - 0.00037 19.1 4.2 0.00043 19.0 2.9 1.0 1 0 0 1 1 1 1 Predicted transmembrane and coiled-coil 2 protein PIN_2 PF10130.4 AIO01530.1 - 0.0051 16.8 0.3 0.0068 16.4 0.2 1.1 1 0 0 1 1 1 1 PIN domain nsp8 PF08717.5 AIO01530.1 - 0.058 12.9 0.2 0.076 12.6 0.2 1.1 1 0 0 1 1 1 0 nsp8 replicase DUF904 PF06005.7 AIO01530.1 - 0.082 13.2 5.2 2.7 8.3 3.6 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF904) Tup_N PF08581.5 AIO01530.1 - 0.084 13.0 1.4 0.12 12.5 1.0 1.3 1 0 0 1 1 1 0 Tup N-terminal FlxA PF14282.1 AIO01530.1 - 0.09 12.7 3.9 0.25 11.3 2.7 1.7 1 1 0 1 1 1 0 FlxA-like protein Macoilin PF09726.4 AIO01530.1 - 0.16 10.2 3.2 0.19 9.9 2.2 1.0 1 0 0 1 1 1 0 Transmembrane protein IncA PF04156.9 AIO01530.1 - 0.29 10.6 2.0 0.31 10.6 1.4 1.1 1 0 0 1 1 1 0 IncA protein ATG19_autophagy PF12744.2 AIO01531.1 - 0.12 11.6 0.3 0.15 11.2 0.2 1.1 1 0 0 1 1 1 0 Autophagy protein Atg19, Atg8-binding DUF4407 PF14362.1 AIO01531.1 - 0.12 11.2 3.0 0.14 11.0 2.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) LMBR1 PF04791.11 AIO01531.1 - 0.36 9.3 1.2 0.43 9.1 0.8 1.0 1 0 0 1 1 1 0 LMBR1-like membrane protein zf-MYND PF01753.13 AIO01532.1 - 1.9e-08 34.0 12.1 3.7e-08 33.0 8.4 1.5 1 0 0 1 1 1 1 MYND finger HTH_29 PF13551.1 AIO01532.1 - 0.038 14.1 0.0 0.083 13.0 0.0 1.6 1 0 0 1 1 1 0 Winged helix-turn helix Pkinase PF00069.20 AIO01533.1 - 3.2e-54 183.8 0.0 2.5e-49 167.7 0.0 2.4 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 AIO01533.1 - 2.3e-39 135.0 0.0 4.3e-37 127.5 0.0 2.6 3 0 0 3 3 3 2 Protein tyrosine kinase Kinase-like PF14531.1 AIO01533.1 - 2.4e-05 23.4 0.0 6.9e-05 21.9 0.0 1.6 1 1 1 2 2 2 1 Kinase-like Kdo PF06293.9 AIO01533.1 - 0.00018 20.6 0.0 0.00036 19.6 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 AIO01533.1 - 0.0044 16.7 0.2 0.65 9.6 0.0 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family RIO1 PF01163.17 AIO01533.1 - 0.0066 15.8 0.0 0.015 14.6 0.0 1.5 1 1 1 2 2 2 1 RIO1 family Epimerase PF01370.16 AIO01534.1 - 9.6e-39 133.2 0.0 1.6e-38 132.4 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 AIO01534.1 - 1.1e-14 53.9 0.0 8e-14 51.2 0.0 2.0 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein Epimerase_Csub PF13950.1 AIO01534.1 - 3.9e-12 45.9 0.0 6.9e-12 45.1 0.0 1.4 1 0 0 1 1 1 1 UDP-glucose 4-epimerase C-term subunit 3Beta_HSD PF01073.14 AIO01534.1 - 1.7e-11 43.3 0.0 5e-10 38.5 0.0 2.3 2 1 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 AIO01534.1 - 1.1e-09 37.6 0.0 1.6e-09 37.0 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein KR PF08659.5 AIO01534.1 - 4e-07 29.8 0.0 1.4e-06 28.0 0.0 1.9 2 1 0 2 2 2 1 KR domain RmlD_sub_bind PF04321.12 AIO01534.1 - 8.6e-06 24.8 0.0 7.3e-05 21.7 0.0 2.2 1 1 0 1 1 1 1 RmlD substrate binding domain adh_short PF00106.20 AIO01534.1 - 2.6e-05 24.2 0.0 5.7e-05 23.0 0.0 1.6 1 0 0 1 1 1 1 short chain dehydrogenase DUF4232 PF14016.1 AIO01534.1 - 0.018 14.7 0.0 0.032 13.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4232) Semialdhyde_dh PF01118.19 AIO01534.1 - 0.029 14.6 0.0 0.058 13.6 0.0 1.5 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain TrkA_N PF02254.13 AIO01534.1 - 0.046 13.7 0.1 2.3 8.2 0.0 2.9 3 0 0 3 3 3 0 TrkA-N domain DUF1800 PF08811.6 AIO01534.1 - 0.11 11.4 0.0 0.16 10.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1800) Saccharop_dh PF03435.13 AIO01534.1 - 0.15 11.0 0.0 0.23 10.3 0.0 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase CDC45 PF02724.9 AIO01536.1 - 9.5e-123 410.4 0.0 6.5e-122 407.6 0.0 1.9 1 1 0 1 1 1 1 CDC45-like protein TFIIA PF03153.8 AIO01536.1 - 8.5 6.1 9.0 15 5.3 6.2 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit HALZ PF02183.13 AIO01537.1 - 0.015 15.0 14.0 0.55 10.0 0.3 4.5 4 0 0 4 4 4 0 Homeobox associated leucine zipper DUF500 PF04366.7 AIO01537.1 - 0.056 12.8 0.1 0.21 11.0 0.1 1.9 1 0 0 1 1 1 0 Family of unknown function (DUF500) DUF342 PF03961.8 AIO01537.1 - 1.5 7.1 6.0 0.6 8.4 2.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF342) Spc7 PF08317.6 AIO01537.1 - 7.7 5.0 26.4 0.071 11.7 11.1 2.4 3 0 0 3 3 3 0 Spc7 kinetochore protein CoA_trans PF01144.18 AIO01538.1 - 2.6e-99 330.7 1.7 4.2e-61 205.8 0.3 2.0 2 0 0 2 2 2 2 Coenzyme A transferase AcetylCoA_hyd_C PF13336.1 AIO01538.1 - 0.0099 15.5 0.0 0.018 14.6 0.0 1.5 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase C-terminal domain NCA2 PF08637.5 AIO01539.1 - 2.4e-39 134.9 0.0 3e-30 105.1 0.0 2.1 2 0 0 2 2 2 2 ATP synthase regulation protein NCA2 GRASP55_65 PF04495.9 AIO01541.1 - 2.7e-41 140.8 0.0 7e-36 123.2 0.0 2.2 1 1 1 2 2 2 2 GRASP55/65 PDZ-like domain Op_neuropeptide PF08035.6 AIO01541.1 - 0.084 12.4 0.0 0.26 10.9 0.0 1.8 1 0 0 1 1 1 0 Opioids neuropeptide HSP90 PF00183.13 AIO01542.1 - 4.3e-73 246.5 3.3 2e-72 244.2 0.5 2.0 1 1 1 2 2 2 2 Hsp90 protein HATPase_c_3 PF13589.1 AIO01542.1 - 9.8e-13 47.9 0.1 2.4e-12 46.6 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 AIO01542.1 - 2.1e-06 27.4 0.0 4.5e-06 26.3 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Ski_Sno PF02437.12 AIO01542.1 - 0.074 12.6 0.0 0.18 11.3 0.0 1.6 1 0 0 1 1 1 0 SKI/SNO/DAC family MMR_HSR1 PF01926.18 AIO01543.1 - 1e-18 67.3 0.1 1.4e-13 50.8 0.0 2.4 2 0 0 2 2 2 2 50S ribosome-binding GTPase FeoB_N PF02421.13 AIO01543.1 - 1.1e-10 41.0 2.1 1.2e-08 34.3 0.1 2.8 3 0 0 3 3 3 2 Ferrous iron transport protein B GTP_EFTU PF00009.22 AIO01543.1 - 1.4e-05 24.5 0.2 0.00028 20.3 0.1 2.6 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain Dynamin_N PF00350.18 AIO01543.1 - 0.00053 19.8 0.9 0.043 13.6 0.1 3.1 2 1 1 3 3 3 1 Dynamin family DUF258 PF03193.11 AIO01543.1 - 0.0012 18.0 0.1 0.025 13.7 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function, DUF258 Taeniidae_ag PF05596.6 AIO01543.1 - 0.027 14.2 0.0 0.097 12.4 0.0 1.9 1 0 0 1 1 1 0 Taeniidae antigen Miro PF08477.8 AIO01543.1 - 0.031 14.7 0.1 1.1 9.7 0.0 2.5 2 0 0 2 2 2 0 Miro-like protein ArgK PF03308.11 AIO01543.1 - 0.034 12.9 0.0 0.074 11.8 0.0 1.5 1 0 0 1 1 1 0 ArgK protein AAA_17 PF13207.1 AIO01543.1 - 0.13 13.1 1.8 0.27 12.0 0.0 2.5 3 0 0 3 3 3 0 AAA domain Diphthamide_syn PF01866.12 AIO01544.1 - 3.6e-33 115.1 0.9 1.3e-18 67.2 0.0 2.3 2 0 0 2 2 2 2 Putative diphthamide synthesis protein IncA PF04156.9 AIO01546.1 - 5.8 6.4 22.1 0.028 14.0 2.3 3.1 3 0 0 3 3 3 0 IncA protein RILP PF11461.3 AIO01548.1 - 0.016 15.3 0.0 0.065 13.3 0.0 2.0 2 0 0 2 2 2 0 Rab interacting lysosomal protein Bax1-I PF01027.15 AIO01549.1 - 0.011 15.3 9.7 0.011 15.3 6.7 1.9 3 0 0 3 3 3 0 Inhibitor of apoptosis-promoting Bax1 Tox-WTIP PF15654.1 AIO01549.1 - 0.022 14.3 0.1 0.081 12.5 0.1 2.0 1 0 0 1 1 1 0 Toxin with a conserved tryptophan and TIP tripeptide motif Rad51 PF08423.6 AIO01551.1 - 1.3e-23 83.2 0.7 7.9e-18 64.2 0.0 4.3 2 1 0 4 4 4 3 Rad51 AAA_25 PF13481.1 AIO01551.1 - 2.4e-10 40.1 0.0 6.2e-10 38.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain KaiC PF06745.8 AIO01551.1 - 1.9e-05 23.8 0.4 6.8e-05 22.0 0.1 1.9 2 0 0 2 2 2 1 KaiC AAA_19 PF13245.1 AIO01551.1 - 0.00088 18.9 0.0 0.0043 16.7 0.0 2.2 1 0 0 1 1 1 1 Part of AAA domain RecA PF00154.16 AIO01551.1 - 0.0018 17.4 0.1 0.0035 16.4 0.1 1.4 1 0 0 1 1 1 1 recA bacterial DNA recombination protein AAA PF00004.24 AIO01551.1 - 0.087 13.0 0.1 0.34 11.0 0.0 2.0 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Radial_spoke PF04712.7 AIO01552.1 - 5e-09 35.4 0.0 8.6e-07 28.0 0.0 2.9 2 1 0 2 2 2 2 Radial spokehead-like protein UDPGP PF01704.13 AIO01554.1 - 2.9e-27 95.2 0.0 4.3e-27 94.6 0.0 1.2 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase NTP_transf_3 PF12804.2 AIO01554.1 - 0.00043 20.4 2.0 0.00093 19.2 0.1 2.4 3 0 0 3 3 3 1 MobA-like NTP transferase domain NUC173 PF08161.7 AIO01555.1 - 3.5e-13 49.3 0.2 1.8e-12 47.0 0.1 2.4 1 0 0 1 1 1 1 NUC173 domain Peptidase_M32 PF02074.10 AIO01556.1 - 1.6e-122 409.6 0.1 1.8e-122 409.5 0.0 1.0 1 0 0 1 1 1 1 Carboxypeptidase Taq (M32) metallopeptidase Iso_dh PF00180.15 AIO01557.1 - 5.5e-105 351.1 0.0 7.3e-105 350.7 0.0 1.2 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase PdxA PF04166.7 AIO01557.1 - 0.0033 16.6 0.2 0.0054 15.9 0.1 1.2 1 0 0 1 1 1 1 Pyridoxal phosphate biosynthetic protein PdxA Kinesin PF00225.18 AIO01558.1 - 1.4e-101 339.5 0.3 2.7e-101 338.6 0.2 1.5 1 0 0 1 1 1 1 Kinesin motor domain Miro PF08477.8 AIO01558.1 - 3.8e-05 24.1 0.0 0.00013 22.4 0.0 2.0 1 0 0 1 1 1 1 Miro-like protein AAA_16 PF13191.1 AIO01558.1 - 7.9e-05 22.7 1.8 0.011 15.7 0.0 3.9 4 0 0 4 4 4 1 AAA ATPase domain AAA_22 PF13401.1 AIO01558.1 - 0.00033 20.8 2.6 0.042 13.9 0.0 3.3 3 0 0 3 3 3 1 AAA domain FtsK_SpoIIIE PF01580.13 AIO01558.1 - 0.00078 18.9 2.1 4.4 6.7 0.2 3.9 4 0 0 4 4 4 2 FtsK/SpoIIIE family DUF258 PF03193.11 AIO01558.1 - 0.0023 17.1 0.2 0.0055 15.9 0.2 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Ras PF00071.17 AIO01558.1 - 0.0034 16.8 0.0 0.37 10.1 0.0 2.9 3 0 0 3 3 3 1 Ras family IstB_IS21 PF01695.12 AIO01558.1 - 0.0045 16.4 0.0 0.46 9.8 0.0 2.6 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_28 PF13521.1 AIO01558.1 - 0.0055 16.6 0.0 0.021 14.8 0.0 2.0 1 0 0 1 1 1 1 AAA domain AAA_10 PF12846.2 AIO01558.1 - 0.011 15.1 0.2 0.12 11.7 0.0 2.4 2 0 0 2 2 2 0 AAA-like domain Mg_chelatase PF01078.16 AIO01558.1 - 0.014 14.5 0.0 0.29 10.2 0.0 2.5 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_29 PF13555.1 AIO01558.1 - 0.016 14.7 0.0 0.12 11.8 0.0 2.3 2 0 0 2 2 2 0 P-loop containing region of AAA domain RNA_helicase PF00910.17 AIO01558.1 - 0.029 14.5 0.4 3.6 7.8 0.0 3.7 3 0 0 3 3 3 0 RNA helicase ABC_tran PF00005.22 AIO01558.1 - 0.039 14.2 0.1 0.19 12.0 0.0 2.2 2 0 0 2 2 2 0 ABC transporter MMR_HSR1 PF01926.18 AIO01558.1 - 0.049 13.5 0.5 3.6 7.5 0.1 2.9 3 0 0 3 3 2 0 50S ribosome-binding GTPase NACHT PF05729.7 AIO01558.1 - 0.068 12.8 0.2 0.69 9.5 0.0 2.5 2 0 0 2 2 2 0 NACHT domain AAA_24 PF13479.1 AIO01558.1 - 0.19 11.3 0.3 3.7 7.0 0.0 2.3 2 0 0 2 2 2 0 AAA domain G-alpha PF00503.15 AIO01558.1 - 0.44 9.1 0.0 1.4 7.4 0.0 1.7 2 0 0 2 2 2 0 G-protein alpha subunit Peptidase_M17 PF00883.16 AIO01559.1 - 2.2e-82 276.4 0.0 3e-82 275.9 0.0 1.2 1 0 0 1 1 1 1 Cytosol aminopeptidase family, catalytic domain NapE PF06796.6 AIO01560.1 - 0.54 9.6 2.5 0.88 8.9 1.7 1.3 1 0 0 1 1 1 0 Periplasmic nitrate reductase protein NapE 3HCDH_N PF02737.13 AIO01563.1 - 3.5e-42 144.0 0.0 6.7e-42 143.1 0.0 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ECH PF00378.15 AIO01563.1 - 1.6e-36 125.6 0.0 2.6e-36 124.9 0.0 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family 3HCDH PF00725.17 AIO01563.1 - 2.7e-20 72.5 0.0 2.8e-09 37.2 0.0 3.5 3 0 0 3 3 3 2 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain NAD_binding_9 PF13454.1 AIO01563.1 - 0.0074 16.0 0.0 0.014 15.2 0.0 1.4 1 0 0 1 1 1 1 FAD-NAD(P)-binding DAO PF01266.19 AIO01563.1 - 0.011 14.6 0.1 0.022 13.6 0.1 1.5 1 0 0 1 1 1 0 FAD dependent oxidoreductase TrkA_N PF02254.13 AIO01563.1 - 0.052 13.5 0.0 0.14 12.2 0.0 1.7 1 0 0 1 1 1 0 TrkA-N domain NAD_Gly3P_dh_N PF01210.18 AIO01563.1 - 0.056 13.1 0.0 0.14 11.8 0.0 1.7 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Pyr_redox_2 PF07992.9 AIO01563.1 - 0.069 13.0 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Peptidase_M16_C PF05193.16 AIO01564.1 - 2.3e-21 76.2 0.0 4.3e-21 75.4 0.0 1.5 1 0 0 1 1 1 1 Peptidase M16 inactive domain Peptidase_M16 PF00675.15 AIO01564.1 - 2.3e-06 27.4 0.0 4.2e-06 26.5 0.0 1.5 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) SRPRB PF09439.5 AIO01565.1 - 2.6e-21 75.6 0.0 5.1e-21 74.7 0.0 1.4 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.22 AIO01565.1 - 5.3e-06 25.9 0.1 1.4e-05 24.6 0.0 1.7 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 AIO01565.1 - 0.00065 19.6 0.0 0.0013 18.7 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 AIO01565.1 - 0.0074 16.7 0.0 0.017 15.5 0.0 1.5 1 0 0 1 1 1 1 Miro-like protein WD40 PF00400.27 AIO01566.1 - 4.3e-09 35.9 0.2 0.041 13.7 0.0 4.8 4 0 0 4 4 4 3 WD domain, G-beta repeat LIM PF00412.17 AIO01567.1 - 4.1e-06 26.7 1.2 7e-06 26.0 0.9 1.4 1 0 0 1 1 1 1 LIM domain Fer4_2 PF12797.2 AIO01567.1 - 0.14 12.1 3.8 2.1 8.4 0.2 2.6 2 0 0 2 2 2 0 4Fe-4S binding domain DUF4193 PF13834.1 AIO01567.1 - 0.28 11.3 5.6 0.32 11.1 0.8 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4193) ThiF PF00899.16 AIO01568.1 - 0.025 14.4 0.0 0.046 13.5 0.0 1.4 1 0 0 1 1 1 0 ThiF family MoeZ_MoeB PF05237.8 AIO01568.1 - 0.13 11.8 0.3 0.39 10.3 0.0 1.9 2 0 0 2 2 2 0 MoeZ/MoeB domain zf-CCHC_4 PF14392.1 AIO01569.1 - 0.45 10.2 7.3 0.92 9.2 0.7 2.6 2 0 0 2 2 2 0 Zinc knuckle DnaJ PF00226.26 AIO01572.1 - 6.9e-10 38.5 0.0 2.2e-09 36.8 0.0 1.9 1 0 0 1 1 1 1 DnaJ domain Mnd1 PF03962.10 AIO01572.1 - 2.4 7.8 11.5 0.58 9.7 4.6 2.0 2 0 0 2 2 2 0 Mnd1 family MCM PF00493.18 AIO01573.1 - 9.3e-112 373.0 0.0 1.3e-111 372.5 0.0 1.2 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 AIO01573.1 - 5.5e-17 62.3 0.0 1.4e-16 61.0 0.0 1.7 2 0 0 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.16 AIO01573.1 - 1.2e-08 34.3 0.2 5.9e-07 28.8 0.0 2.6 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.21 AIO01573.1 - 0.00037 20.0 0.0 0.0019 17.6 0.0 2.0 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_3 PF07726.6 AIO01573.1 - 0.0024 17.4 0.0 0.0054 16.3 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ATG_C PF09333.6 AIO01573.1 - 0.012 15.7 0.1 1.1 9.4 0.0 2.6 2 0 0 2 2 2 0 ATG C terminal domain AAA_5 PF07728.9 AIO01573.1 - 0.065 12.9 0.0 0.29 10.8 0.0 2.1 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA PF00004.24 AIO01573.1 - 0.085 13.0 0.0 0.18 11.9 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Complex1_LYR PF05347.10 AIO01574.1 - 1.2e-06 28.2 0.7 2.2e-06 27.3 0.5 1.4 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 AIO01574.1 - 0.0038 17.4 1.3 0.0065 16.6 0.9 1.4 1 0 0 1 1 1 1 Complex1_LYR-like Misat_Tub_SegII PF10644.4 AIO01574.1 - 0.12 12.4 0.0 0.14 12.1 0.0 1.2 1 0 0 1 1 1 0 Misato Segment II tubulin-like domain ketoacyl-synt PF00109.21 AIO01575.1 - 2.7e-39 135.1 3.8 9.3e-38 130.1 2.6 2.3 1 1 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.17 AIO01575.1 - 9.8e-27 93.1 0.8 9.8e-27 93.1 0.6 1.9 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain CoA_binding_2 PF13380.1 AIO01576.1 - 0.024 14.7 0.1 0.47 10.6 0.0 2.3 2 0 0 2 2 2 0 CoA binding domain GTP_EFTU PF00009.22 AIO01577.1 - 1.9e-32 112.1 0.0 7.8e-32 110.2 0.0 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain IF-2 PF11987.3 AIO01577.1 - 9.8e-15 54.3 0.0 2.4e-14 53.1 0.0 1.7 1 0 0 1 1 1 1 Translation-initiation factor 2 GTP_EFTU_D2 PF03144.20 AIO01577.1 - 1.5e-10 41.0 1.1 4.6e-07 29.8 0.0 2.9 2 0 0 2 2 2 2 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 AIO01577.1 - 1.1e-06 28.5 0.0 4e-06 26.7 0.0 2.0 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.1 AIO01577.1 - 0.00054 19.9 0.1 0.00054 19.9 0.1 2.5 2 1 0 2 2 2 1 AAA ATPase domain GTP_EFTU_D4 PF14578.1 AIO01577.1 - 0.0012 18.4 0.2 0.0035 16.9 0.1 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 4 ATP_bind_1 PF03029.12 AIO01577.1 - 0.0014 18.2 0.0 0.0048 16.4 0.0 1.9 1 1 0 1 1 1 1 Conserved hypothetical ATP binding protein Miro PF08477.8 AIO01577.1 - 0.0017 18.8 0.0 0.0068 16.8 0.0 2.1 1 0 0 1 1 1 1 Miro-like protein Ras PF00071.17 AIO01577.1 - 0.013 14.9 0.0 0.063 12.6 0.0 2.1 1 1 0 1 1 1 0 Ras family Dynamin_N PF00350.18 AIO01577.1 - 4.3 7.1 21.3 0.077 12.8 3.7 4.2 1 1 0 2 2 2 0 Dynamin family DUF4520 PF15016.1 AIO01578.1 - 1.1e-27 95.3 0.1 4.8e-24 83.7 0.0 2.7 2 0 0 2 2 2 2 Domain of unknown function (DUF4520) POLO_box PF00659.13 AIO01578.1 - 0.065 13.2 0.0 0.35 10.8 0.0 2.1 2 0 0 2 2 2 0 POLO box duplicated region UQ_con PF00179.21 AIO01580.1 - 1.7e-34 118.2 0.0 2.2e-34 117.8 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 AIO01580.1 - 0.0018 18.0 0.0 0.0026 17.5 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic E2 family B Beach PF02138.13 AIO01581.1 - 1.9e-88 296.4 0.0 3.3e-88 295.6 0.0 1.4 1 0 0 1 1 1 1 Beige/BEACH domain GTP_EFTU PF00009.22 AIO01582.1 - 1.1e-19 70.5 0.0 2.9e-19 69.2 0.0 1.7 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 AIO01582.1 - 1.9e-16 60.0 0.1 8e-16 58.0 0.0 2.0 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 AIO01582.1 - 1.4e-05 25.1 0.6 3.7e-05 23.7 0.4 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MobB PF03205.9 AIO01582.1 - 0.014 15.0 0.1 0.43 10.2 0.0 2.4 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B v110 PF01639.12 AIO01583.1 - 0.047 13.2 0.0 0.089 12.3 0.0 1.4 1 0 0 1 1 1 0 Viral family 110 TFIIS_C PF01096.13 AIO01584.1 - 1.1e-15 56.9 7.3 2e-15 56.1 5.1 1.4 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS) PWWP PF00855.12 AIO01584.1 - 1.7e-07 31.3 0.1 6.4e-07 29.4 0.0 2.0 2 0 0 2 2 2 1 PWWP domain Med26 PF08711.6 AIO01584.1 - 0.0076 15.7 0.0 0.014 14.8 0.0 1.5 1 0 0 1 1 1 1 TFIIS helical bundle-like domain PhnG PF06754.7 AIO01584.1 - 0.048 13.2 2.7 0.05 13.2 0.5 1.9 2 0 0 2 2 2 0 Phosphonate metabolism protein PhnG Baculo_LEF5_C PF11792.3 AIO01584.1 - 0.1 11.9 1.3 0.24 10.8 0.9 1.6 1 0 0 1 1 1 0 Baculoviridae late expression factor 5 C-terminal domain PWWP PF00855.12 AIO01585.1 - 4.3e-11 42.8 1.2 5.8e-11 42.4 0.0 1.9 2 0 0 2 2 2 1 PWWP domain Med26 PF08711.6 AIO01585.1 - 6.7e-11 41.5 0.0 1.1e-10 40.8 0.0 1.4 1 0 0 1 1 1 1 TFIIS helical bundle-like domain Zn_Tnp_IS1595 PF12760.2 AIO01585.1 - 0.044 13.5 0.8 0.044 13.5 0.6 2.1 2 0 0 2 2 2 0 Transposase zinc-ribbon domain zf-DNA_Pol PF08996.5 AIO01585.1 - 0.069 12.4 0.5 0.13 11.5 0.3 1.5 1 0 0 1 1 1 0 DNA Polymerase alpha zinc finger zinc_ribbon_5 PF13719.1 AIO01585.1 - 0.12 11.9 1.8 1.3 8.6 0.0 2.6 2 0 0 2 2 2 0 zinc-ribbon domain zinc_ribbon_4 PF13717.1 AIO01585.1 - 0.44 10.2 2.1 3.7 7.3 0.1 2.6 2 0 0 2 2 2 0 zinc-ribbon domain CHAP PF05257.11 AIO01586.1 - 6.6e-16 58.1 0.2 1.2e-15 57.2 0.1 1.4 1 0 0 1 1 1 1 CHAP domain Amidase_6 PF12671.2 AIO01586.1 - 0.049 13.6 0.0 0.13 12.3 0.0 1.5 1 1 0 1 1 1 0 Putative amidase domain DUF1675 PF07897.6 AIO01587.1 - 0.056 13.2 11.9 0.091 12.6 8.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) DUF1049 PF06305.6 AIO01587.1 - 0.11 11.9 0.4 0.52 9.8 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1049) ABC2_membrane_3 PF12698.2 AIO01587.1 - 0.95 8.4 5.8 0.052 12.5 0.4 1.5 2 0 0 2 2 2 0 ABC-2 family transporter protein CCDC84 PF14968.1 AIO01587.1 - 1.4 8.3 4.1 2.1 7.7 2.8 1.1 1 0 0 1 1 1 0 Coiled coil protein 84 DUF566 PF04484.7 AIO01587.1 - 3.1 7.2 13.4 6.5 6.1 9.3 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF566) Macoilin PF09726.4 AIO01587.1 - 7.2 4.7 12.7 9.8 4.3 8.8 1.1 1 0 0 1 1 1 0 Transmembrane protein CHAP PF05257.11 AIO01588.1 - 2.3e-12 46.6 0.1 5.8e-11 42.1 0.0 2.3 1 1 0 1 1 1 1 CHAP domain CHAP PF05257.11 AIO01589.1 - 6e-05 22.6 0.5 0.0041 16.7 0.0 2.4 2 0 0 2 2 2 2 CHAP domain LST1 PF05083.8 AIO01592.1 - 0.079 12.9 0.0 0.14 12.1 0.0 1.4 1 0 0 1 1 1 0 LST-1 protein PAT1 PF09770.4 AIO01592.1 - 4.2 5.4 16.6 5.1 5.2 11.5 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Sec8_exocyst PF04048.9 AIO01594.1 - 0.088 12.4 0.1 0.53 9.9 0.0 2.3 2 0 0 2 2 2 0 Sec8 exocyst complex component specific domain DUF658 PF04936.7 AIO01602.1 - 0.043 13.6 0.5 0.076 12.8 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF658) TFIIA PF03153.8 AIO01602.1 - 0.75 9.6 22.4 2.7 7.8 15.5 2.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF3454 PF11936.3 AIO01602.1 - 1.8 8.8 17.9 0.58 10.3 10.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3454) RAP1 PF07218.6 AIO01604.1 - 0.82 7.6 7.6 1.5 6.8 5.3 1.3 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) ABC_tran PF00005.22 AIO01606.1 - 3.3e-11 43.6 0.0 4.3e-05 23.8 0.0 2.8 2 0 0 2 2 2 2 ABC transporter SbcCD_C PF13558.1 AIO01606.1 - 0.00068 19.4 0.2 0.0054 16.6 0.0 2.5 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_29 PF13555.1 AIO01606.1 - 0.089 12.3 0.0 0.25 10.9 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF258 PF03193.11 AIO01606.1 - 0.14 11.2 0.0 0.27 10.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 Peptidase_S8 PF00082.17 AIO01606.1 - 0.28 10.2 1.6 2.8 6.9 0.1 2.2 2 0 0 2 2 2 0 Subtilase family Tyr-DNA_phospho PF06087.7 AIO01607.1 - 9.7e-68 228.8 0.0 1.7e-62 211.4 0.0 2.5 1 1 0 2 2 2 2 Tyrosyl-DNA phosphodiesterase OGFr_III PF04680.8 AIO01608.1 - 3.5e-06 26.8 2.9 9.1e-06 25.5 2.0 1.8 1 0 0 1 1 1 1 Opioid growth factor receptor repeat Lipoxygenase PF00305.14 AIO01609.1 - 0.66 7.8 1.2 1 7.2 0.8 1.1 1 0 0 1 1 1 0 Lipoxygenase YqgF PF14639.1 AIO01610.1 - 4.6e-11 42.5 0.0 4.7e-10 39.2 0.0 2.2 2 0 0 2 2 2 1 Holliday-junction resolvase-like of SPT6 SH2_2 PF14633.1 AIO01610.1 - 8e-11 41.4 0.0 1.4e-10 40.6 0.0 1.3 1 0 0 1 1 1 1 SH2 domain Sld5 PF05916.6 AIO01610.1 - 0.028 14.7 0.2 12 6.2 0.0 3.5 3 0 0 3 3 3 0 GINS complex protein MCD PF05292.6 AIO01612.1 - 0.061 12.0 0.0 0.11 11.1 0.0 1.3 1 0 0 1 1 1 0 Malonyl-CoA decarboxylase (MCD) Trypsin_2 PF13365.1 AIO01613.1 - 4.9e-09 36.1 0.0 7.2e-09 35.6 0.0 1.3 1 0 0 1 1 1 1 Trypsin-like peptidase domain Trypsin PF00089.21 AIO01613.1 - 0.048 13.2 0.3 0.1 12.1 0.1 1.6 2 0 0 2 2 2 0 Trypsin Ribosomal_S13_N PF08069.7 AIO01614.1 - 6.7e-25 86.7 2.0 6.7e-25 86.7 1.4 1.7 2 0 0 2 2 2 1 Ribosomal S13/S15 N-terminal domain Ribosomal_S15 PF00312.17 AIO01614.1 - 9.4e-22 76.5 0.4 1.4e-21 75.9 0.3 1.3 1 0 0 1 1 1 1 Ribosomal protein S15 Imm37 PF15598.1 AIO01616.1 - 0.017 15.0 0.0 0.061 13.1 0.0 1.9 2 0 0 2 2 2 0 Immunity protein 37 NPV_P10 PF05531.7 AIO01616.1 - 0.033 14.4 0.6 33 4.8 0.0 3.7 4 0 0 4 4 4 0 Nucleopolyhedrovirus P10 protein Mer2 PF09074.5 AIO01616.1 - 0.039 13.8 0.2 0.096 12.5 0.1 1.7 1 0 0 1 1 1 0 Mer2 Apolipoprotein PF01442.13 AIO01616.1 - 0.048 13.1 9.0 0.083 12.3 0.5 2.7 2 2 0 2 2 2 0 Apolipoprotein A1/A4/E domain HALZ PF02183.13 AIO01616.1 - 0.099 12.3 5.7 0.52 10.0 0.1 3.5 3 0 0 3 3 3 0 Homeobox associated leucine zipper UPF0061 PF02696.9 AIO01616.1 - 0.11 10.8 0.1 6.8 4.8 0.0 2.2 1 1 1 2 2 2 0 Uncharacterized ACR, YdiU/UPF0061 family AAA_13 PF13166.1 AIO01616.1 - 0.27 9.6 0.0 3.5 5.9 0.0 2.1 3 0 0 3 3 3 0 AAA domain HisKA_3 PF07730.8 AIO01616.1 - 2.3 8.6 8.6 29 5.1 0.0 4.6 3 1 0 3 3 3 0 Histidine kinase DUF4381 PF14316.1 AIO01617.1 - 0.033 14.2 0.0 0.081 13.0 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) CoA_binding_3 PF13727.1 AIO01617.1 - 0.081 12.7 0.2 1.1 9.0 0.0 2.2 2 0 0 2 2 2 0 CoA-binding domain EphA2_TM PF14575.1 AIO01617.1 - 0.35 11.2 8.4 1.4 9.3 0.0 4.4 4 2 0 4 4 4 0 Ephrin type-A receptor 2 transmembrane domain LSM PF01423.17 AIO01618.1 - 9.2e-14 50.7 0.2 1.3e-13 50.2 0.1 1.2 1 0 0 1 1 1 1 LSM domain Zip PF02535.17 AIO01619.1 - 1.4e-33 116.2 14.4 1.9e-33 115.8 10.0 1.2 1 0 0 1 1 1 1 ZIP Zinc transporter HupE_UreJ PF04955.7 AIO01619.1 - 2.9 7.1 13.6 0.14 11.4 3.1 2.8 3 0 0 3 3 3 0 HupE / UreJ protein Coatomer_WDAD PF04053.9 AIO01620.1 - 3.1e-136 454.6 0.0 5.3e-136 453.9 0.0 1.4 1 0 0 1 1 1 1 Coatomer WD associated region WD40 PF00400.27 AIO01620.1 - 2e-41 138.3 1.7 1.3e-10 40.6 0.0 6.4 6 0 0 6 6 6 5 WD domain, G-beta repeat TPR_8 PF13181.1 AIO01620.1 - 0.017 14.8 0.1 0.1 12.4 0.0 2.3 3 0 0 3 3 3 0 Tetratricopeptide repeat Clathrin PF00637.15 AIO01620.1 - 0.04 13.5 0.9 1.3 8.5 0.0 2.6 1 1 2 3 3 3 0 Region in Clathrin and VPS zf-RanBP PF00641.13 AIO01621.1 - 8.9e-15 53.4 42.3 1.2e-06 27.5 4.4 5.5 5 0 0 5 5 5 5 Zn-finger in Ran binding protein and others Cytochrome_C7 PF14522.1 AIO01621.1 - 0.00031 20.3 20.5 0.3 10.7 0.3 4.3 2 2 1 3 3 3 2 Cytochrome c7 Haem_bd PF14376.1 AIO01621.1 - 0.0053 16.4 6.3 0.06 13.0 0.0 3.2 3 0 0 3 3 3 1 Haem-binding domain Prok-RING_2 PF14445.1 AIO01621.1 - 0.2 11.6 0.3 0.2 11.6 0.2 4.7 4 1 0 4 4 4 0 Prokaryotic RING finger family 2 Paired_CXXCH_1 PF09699.5 AIO01621.1 - 0.36 10.3 15.5 2.3 7.8 1.3 4.1 3 0 0 3 3 3 0 Doubled CXXCH motif (Paired_CXXCH_1) DZR PF12773.2 AIO01621.1 - 1.3 8.8 32.8 1.3 8.8 0.1 4.7 3 1 2 5 5 5 0 Double zinc ribbon EF-hand_7 PF13499.1 AIO01623.1 - 4.6e-06 26.6 0.1 2.1e-05 24.5 0.0 2.1 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.1 AIO01623.1 - 0.00046 19.8 0.0 0.007 16.1 0.0 2.7 2 0 0 2 2 2 1 EF-hand domain EF-hand_5 PF13202.1 AIO01623.1 - 0.00052 19.2 0.0 0.0013 18.0 0.0 1.7 1 0 0 1 1 1 1 EF hand EF-hand_1 PF00036.27 AIO01623.1 - 0.0017 17.5 0.0 0.027 13.7 0.0 3.0 3 0 0 3 3 3 1 EF hand Ribosomal_L44 PF00935.14 AIO01624.1 - 3e-31 107.2 8.9 4.4e-31 106.7 6.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L44 RPA_interact_C PF14768.1 AIO01624.1 - 0.1 13.0 0.6 0.65 10.4 0.4 1.9 1 1 0 1 1 1 0 Replication protein A interacting C-terminal Drf_FH1 PF06346.7 AIO01625.1 - 0.22 10.9 4.8 0.43 10.0 3.3 1.4 1 1 0 1 1 1 0 Formin Homology Region 1 CCT_2 PF09425.5 AIO01626.1 - 0.11 12.0 3.5 0.41 10.2 0.8 2.6 2 0 0 2 2 2 0 Divergent CCT motif ABC_tran PF00005.22 AIO01627.1 - 2.6e-17 63.4 0.0 4.3e-17 62.6 0.0 1.4 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.14 AIO01627.1 - 0.0007 18.8 0.0 0.013 14.7 0.0 1.9 1 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain Cys_Met_Meta_PP PF01053.15 AIO01627.1 - 0.0027 16.0 0.1 0.0058 14.9 0.0 1.5 2 0 0 2 2 2 1 Cys/Met metabolism PLP-dependent enzyme AAA_29 PF13555.1 AIO01627.1 - 0.026 14.0 0.0 0.059 12.9 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_25 PF13481.1 AIO01627.1 - 0.027 13.8 0.0 0.071 12.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain FA_desaturase PF00487.19 AIO01628.1 - 1.7e-25 89.9 31.1 2.5e-25 89.3 21.6 1.2 1 0 0 1 1 1 1 Fatty acid desaturase PK PF00224.16 AIO01629.1 - 1.4e-160 533.6 1.4 1.8e-160 533.2 1.0 1.1 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.11 AIO01629.1 - 6.3e-27 93.4 0.5 2.2e-26 91.7 0.1 2.1 2 0 0 2 2 2 1 Pyruvate kinase, alpha/beta domain HpcH_HpaI PF03328.9 AIO01629.1 - 1.9e-05 23.6 0.8 6.7e-05 21.8 0.6 1.9 1 1 1 2 2 2 1 HpcH/HpaI aldolase/citrate lyase family Peripla_BP_1 PF00532.16 AIO01629.1 - 0.04 13.1 0.0 0.14 11.2 0.0 2.0 2 0 0 2 2 2 0 Periplasmic binding proteins and sugar binding domain of LacI family PI-PLC-X PF00388.14 AIO01630.1 - 1.3e-58 196.5 0.0 2.5e-58 195.6 0.0 1.5 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.14 AIO01630.1 - 4.3e-33 113.8 0.0 1.1e-32 112.4 0.0 1.7 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain EF-hand_1 PF00036.27 AIO01630.1 - 2.6e-05 23.1 1.9 9.5e-05 21.4 1.3 1.9 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.1 AIO01630.1 - 0.00026 21.0 0.1 0.00064 19.8 0.1 1.7 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_like PF09279.6 AIO01630.1 - 0.00027 20.9 1.6 0.15 12.0 0.0 2.5 1 1 1 2 2 2 2 Phosphoinositide-specific phospholipase C, efhand-like EF-hand_8 PF13833.1 AIO01630.1 - 0.0014 18.1 2.0 0.0019 17.8 0.6 1.8 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_10 PF14788.1 AIO01630.1 - 0.0022 17.5 1.8 0.0055 16.3 1.3 1.7 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.1 AIO01630.1 - 0.0025 17.5 2.3 0.014 15.2 1.3 2.4 2 0 0 2 2 2 1 EF-hand domain EF-hand_4 PF12763.2 AIO01630.1 - 0.0041 16.8 0.0 0.011 15.4 0.0 1.7 1 0 0 1 1 1 1 Cytoskeletal-regulatory complex EF hand C2 PF00168.25 AIO01630.1 - 0.14 11.9 0.0 0.47 10.3 0.0 1.9 2 0 0 2 2 2 0 C2 domain Transket_pyr PF02779.19 AIO01631.1 - 2.5e-39 134.6 0.0 4.9e-39 133.6 0.0 1.5 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.15 AIO01631.1 - 1.8e-34 118.3 0.0 3.6e-34 117.3 0.0 1.5 1 0 0 1 1 1 1 Transketolase, C-terminal domain Shal-type PF11601.3 AIO01631.1 - 0.078 12.5 0.7 0.17 11.4 0.5 1.6 1 0 0 1 1 1 0 Shal-type voltage-gated potassium channels Band_7 PF01145.20 AIO01633.1 - 1.6e-26 93.2 1.9 2.6e-26 92.6 1.3 1.3 1 0 0 1 1 1 1 SPFH domain / Band 7 family TrkH PF02386.11 AIO01634.1 - 9.5e-15 54.0 25.7 3.9e-12 45.4 4.1 4.0 2 2 0 2 2 2 2 Cation transport protein DUF2803 PF10972.3 AIO01635.1 - 0.0035 16.8 2.2 0.0042 16.6 1.0 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF2803) UCR_14kD PF02271.11 AIO01636.1 - 6.2e-09 35.5 0.0 1.5e-08 34.3 0.0 1.5 2 0 0 2 2 2 1 Ubiquinol-cytochrome C reductase complex 14kD subunit BIR PF00653.16 AIO01636.1 - 0.034 14.5 0.3 0.07 13.5 0.2 1.5 1 0 0 1 1 1 0 Inhibitor of Apoptosis domain Clat_adaptor_s PF01217.15 AIO01637.1 - 9.4e-11 41.6 0.0 1.3e-10 41.1 0.0 1.1 1 0 0 1 1 1 1 Clathrin adaptor complex small chain LMBR1 PF04791.11 AIO01638.1 - 9e-15 54.2 31.7 6.4e-10 38.2 4.9 2.5 1 1 1 2 2 2 2 LMBR1-like membrane protein Arf PF00025.16 AIO01639.1 - 9.5e-65 217.0 0.1 1.1e-64 216.9 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.15 AIO01639.1 - 5.1e-13 48.4 2.7 2.9e-08 32.8 0.2 2.4 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.7 AIO01639.1 - 3.6e-11 42.6 0.0 4.2e-11 42.4 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.5 AIO01639.1 - 1.9e-07 30.4 0.0 2.5e-07 30.0 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Miro PF08477.8 AIO01639.1 - 2.9e-07 31.0 0.0 3.8e-07 30.6 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Ras PF00071.17 AIO01639.1 - 6.2e-07 28.9 0.0 7.5e-07 28.6 0.0 1.1 1 0 0 1 1 1 1 Ras family GTP_EFTU PF00009.22 AIO01639.1 - 8.1e-07 28.6 0.0 3e-05 23.5 0.0 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 AIO01639.1 - 1.2e-06 28.4 0.0 1.8e-06 27.8 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 AIO01639.1 - 0.00096 18.4 0.1 0.0041 16.4 0.1 1.9 1 1 0 1 1 1 1 Ferrous iron transport protein B cobW PF02492.14 AIO01639.1 - 0.016 14.6 0.1 0.21 11.0 0.0 2.0 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain DUF1902 PF08972.6 AIO01639.1 - 0.11 12.1 0.0 3.7 7.1 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1902) Mito_carr PF00153.22 AIO01641.1 - 2.8e-08 33.3 1.4 0.0025 17.4 0.2 2.7 2 1 0 2 2 2 2 Mitochondrial carrier protein Striatin PF08232.7 AIO01643.1 - 3.4 7.9 12.7 1 9.6 1.4 3.2 2 2 0 2 2 2 0 Striatin family DUF2353 PF09789.4 AIO01644.1 - 0.0036 16.6 25.6 0.0036 16.6 17.7 5.7 1 1 4 6 6 6 2 Uncharacterized coiled-coil protein (DUF2353) Bap31 PF05529.7 AIO01644.1 - 0.0063 15.9 2.9 0.0063 15.9 2.0 7.7 5 3 1 6 6 6 1 B-cell receptor-associated protein 31-like Reo_sigmaC PF04582.7 AIO01644.1 - 0.081 12.0 48.0 0.056 12.6 2.1 7.0 2 2 4 7 7 7 0 Reovirus sigma C capsid protein NIF PF03031.13 AIO01645.1 - 9.4e-33 113.1 0.0 1.3e-32 112.6 0.0 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Hydrolase PF00702.21 AIO01645.1 - 0.0064 16.9 0.0 0.0084 16.5 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 AIO01645.1 - 0.013 15.6 0.0 0.033 14.4 0.0 1.5 1 1 0 1 1 1 0 Haloacid dehalogenase-like hydrolase HAD PF12710.2 AIO01645.1 - 0.015 15.4 0.0 0.03 14.4 0.0 1.5 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase DUF705 PF05152.7 AIO01645.1 - 0.068 12.1 0.0 0.1 11.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF705) SapA PF02199.10 AIO01645.1 - 0.12 12.1 0.3 0.28 10.9 0.2 1.6 1 0 0 1 1 1 0 Saposin A-type domain KH_5 PF13184.1 AIO01646.1 - 0.064 13.0 0.3 4.5 7.1 0.0 3.4 2 0 0 2 2 2 0 NusA-like KH domain DUF1242 PF06842.7 AIO01647.1 - 9.7e-13 47.3 1.7 1.4e-12 46.8 1.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1242) DnaJ PF00226.26 AIO01649.1 - 0.00024 20.7 0.0 0.022 14.5 0.0 2.4 2 0 0 2 2 2 2 DnaJ domain zf-CCCH PF00642.19 AIO01649.1 - 4.5 7.0 8.8 0.2 11.3 2.0 1.9 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Ribosomal_L7Ae PF01248.21 AIO01650.1 - 4.5e-25 86.9 0.0 5.1e-25 86.8 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Hydrolase_6 PF13344.1 AIO01650.1 - 0.082 12.8 0.0 0.11 12.4 0.0 1.2 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase ArfGap PF01412.13 AIO01652.1 - 2.1e-28 98.4 0.1 4.1e-28 97.4 0.1 1.4 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf 3HCDH PF00725.17 AIO01656.1 - 2.3e-11 43.9 0.1 8.8e-05 22.8 0.0 2.6 2 0 0 2 2 2 2 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain Drc1-Sld2 PF11719.3 AIO01657.1 - 0.046 12.8 1.6 0.1 11.7 0.2 1.9 2 0 0 2 2 2 0 DNA replication and checkpoint protein Ank_2 PF12796.2 AIO01658.1 - 2.1e-14 53.6 0.1 9.5e-13 48.3 0.0 2.2 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 AIO01658.1 - 3.8e-12 45.3 0.1 0.00011 21.7 0.0 3.5 3 0 0 3 3 3 3 Ankyrin repeat Ank_3 PF13606.1 AIO01658.1 - 9.7e-10 37.7 0.1 0.0038 17.3 0.0 3.5 3 0 0 3 3 3 3 Ankyrin repeat Ank_4 PF13637.1 AIO01658.1 - 5.3e-09 36.3 0.0 7.3e-05 23.1 0.0 2.8 1 1 0 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.1 AIO01658.1 - 3.2e-08 33.5 0.1 3.2e-05 24.0 0.0 3.0 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Aminotran_1_2 PF00155.16 AIO01659.1 - 1.6e-48 165.4 0.0 2e-48 165.2 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 AIO01659.1 - 5.3e-05 22.5 0.0 8.3e-05 21.8 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.12 AIO01659.1 - 0.0033 16.5 0.0 0.024 13.7 0.0 2.0 1 1 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family adh_short PF00106.20 AIO01660.1 - 1.8e-30 106.0 1.8 2.9e-30 105.3 1.3 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 AIO01660.1 - 3.6e-16 59.3 1.8 6.6e-16 58.4 1.2 1.4 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 AIO01660.1 - 7.2e-12 45.5 0.1 9.5e-12 45.1 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Eno-Rase_NADH_b PF12242.3 AIO01660.1 - 0.014 15.1 0.0 0.047 13.4 0.0 1.9 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Polysacc_synt_2 PF02719.10 AIO01660.1 - 0.022 13.6 0.0 0.027 13.3 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein 7kD_coat PF02495.12 AIO01660.1 - 0.11 11.9 0.2 0.23 10.9 0.2 1.5 1 0 0 1 1 1 0 7kD viral coat protein AtpR PF12966.2 AIO01660.1 - 0.32 11.1 3.0 0.32 11.1 0.1 2.5 3 0 0 3 3 3 0 N-ATPase, AtpR subunit Methyltransf_26 PF13659.1 AIO01661.1 - 0.013 15.5 0.1 0.043 13.8 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain ECH PF00378.15 AIO01663.1 - 1e-54 185.2 1.5 2.9e-54 183.7 1.0 1.6 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family DEAD PF00270.24 AIO01664.1 - 2e-43 147.7 0.5 2.9e-43 147.3 0.4 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 AIO01664.1 - 5e-25 87.1 0.3 1.1e-24 86.0 0.2 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_22 PF13401.1 AIO01664.1 - 0.011 15.8 0.4 0.037 14.1 0.3 1.9 1 1 0 1 1 1 0 AAA domain AAA PF00004.24 AIO01664.1 - 0.12 12.5 1.0 1.9 8.6 0.7 2.6 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Thioredoxin PF00085.15 AIO01665.1 - 1.1e-05 25.0 0.0 2.3e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.1 AIO01665.1 - 3e-05 24.0 0.1 0.014 15.4 0.0 2.4 1 1 1 2 2 2 2 Thioredoxin-like Thioredoxin_7 PF13899.1 AIO01665.1 - 0.0046 16.9 0.4 0.019 14.9 0.0 2.2 3 0 0 3 3 3 1 Thioredoxin-like Thioredoxin_9 PF14595.1 AIO01665.1 - 0.034 13.6 0.0 0.075 12.6 0.0 1.5 1 0 0 1 1 1 0 Thioredoxin Thioredoxin_2 PF13098.1 AIO01665.1 - 0.11 12.7 0.0 0.63 10.2 0.0 2.1 1 1 0 1 1 1 0 Thioredoxin-like domain Ribosomal_S3Ae PF01015.13 AIO01667.1 - 2.8e-61 206.2 4.7 3.2e-61 206.0 3.3 1.0 1 0 0 1 1 1 1 Ribosomal S3Ae family DNA_pol3_delt_C PF14840.1 AIO01667.1 - 0.11 12.6 2.7 0.17 11.9 1.5 1.5 1 1 0 1 1 1 0 Processivity clamp loader gamma complex DNA pol III C-term SHIPPO-rpt PF07004.7 AIO01668.1 - 1.8e-19 69.5 16.1 3.7e-05 24.3 0.1 9.9 9 0 0 9 9 9 7 Sperm-tail PG-rich repeat Arrestin_N PF00339.24 AIO01669.1 - 6e-07 29.3 0.0 1.5e-06 28.1 0.0 1.6 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain HAP2-GCS1 PF10699.4 AIO01670.1 - 5e-21 74.3 0.0 1.2e-20 73.2 0.0 1.7 1 0 0 1 1 1 1 Male gamete fusion factor Pkinase PF00069.20 AIO01671.1 - 1.6e-52 178.2 0.3 3.5e-37 127.9 0.1 3.2 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 AIO01671.1 - 1e-23 83.7 0.3 3.6e-17 62.3 0.1 3.2 3 0 0 3 3 3 2 Protein tyrosine kinase EF-hand_6 PF13405.1 AIO01671.1 - 5.1e-08 32.1 0.1 0.013 15.3 0.0 3.1 3 0 0 3 3 3 2 EF-hand domain EF-hand_7 PF13499.1 AIO01671.1 - 2.1e-06 27.7 0.8 0.05 13.7 0.1 2.6 2 0 0 2 2 2 2 EF-hand domain pair Kinase-like PF14531.1 AIO01671.1 - 8.5e-05 21.6 0.0 0.16 10.8 0.0 2.2 2 0 0 2 2 2 2 Kinase-like EF-hand_1 PF00036.27 AIO01671.1 - 0.00015 20.7 0.0 0.19 11.0 0.0 3.2 3 0 0 3 3 3 2 EF hand Kdo PF06293.9 AIO01671.1 - 0.062 12.3 0.0 0.13 11.3 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family LRR_4 PF12799.2 AIO01672.1 - 1.6e-19 69.0 14.4 1.9e-05 24.1 1.3 8.0 3 2 7 10 10 10 7 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 AIO01672.1 - 4.5e-17 61.5 13.4 6.3e-05 22.6 0.2 5.9 4 2 3 7 7 7 6 Leucine rich repeat LRR_1 PF00560.28 AIO01672.1 - 2.2e-11 42.1 5.3 0.17 12.0 0.2 9.2 11 0 0 11 11 11 3 Leucine Rich Repeat LRR_6 PF13516.1 AIO01672.1 - 0.023 14.7 13.6 8.3 6.8 0.8 6.9 7 1 1 8 8 8 0 Leucine Rich repeat LRR_4 PF12799.2 AIO01673.1 - 2.7e-18 65.1 15.6 0.00044 19.8 0.6 6.9 6 2 2 8 8 8 5 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 AIO01673.1 - 4.1e-13 47.3 13.0 0.77 10.0 0.0 11.3 12 0 0 12 12 12 3 Leucine Rich Repeat LRR_8 PF13855.1 AIO01673.1 - 4.7e-13 48.6 11.8 7.7e-05 22.3 0.3 4.9 3 2 2 6 6 6 4 Leucine rich repeat FNIP PF05725.7 AIO01673.1 - 0.00036 20.4 2.0 0.69 9.9 0.0 4.5 5 1 0 5 5 5 2 FNIP Repeat LRR_6 PF13516.1 AIO01673.1 - 0.0014 18.4 11.7 17 5.8 0.0 8.1 8 1 1 9 9 9 1 Leucine Rich repeat Lum_binding PF00677.12 AIO01673.1 - 0.097 12.5 0.0 0.36 10.7 0.0 2.0 1 0 0 1 1 1 0 Lumazine binding domain LRR_7 PF13504.1 AIO01673.1 - 0.11 12.7 15.7 2.2 8.8 0.1 7.2 8 0 0 8 8 8 0 Leucine rich repeat DUF3079 PF11278.3 AIO01673.1 - 0.47 10.0 3.8 0.61 9.6 0.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3079) LRR_8 PF13855.1 AIO01674.1 - 1.9e-10 40.3 2.1 0.00032 20.3 0.2 2.4 2 0 0 2 2 2 2 Leucine rich repeat LRR_4 PF12799.2 AIO01674.1 - 1.9e-09 36.9 6.3 0.00031 20.3 0.1 3.4 2 1 3 5 5 5 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 AIO01674.1 - 3.2e-09 35.5 4.4 0.26 11.4 0.0 5.1 5 0 0 5 5 5 3 Leucine Rich Repeat LRR_6 PF13516.1 AIO01674.1 - 8e-05 22.3 7.0 2.4 8.4 0.1 4.5 5 0 0 5 5 5 2 Leucine Rich repeat FNIP PF05725.7 AIO01674.1 - 0.01 15.7 4.0 2.5 8.1 1.8 3.7 1 1 1 2 2 2 0 FNIP Repeat LRR_7 PF13504.1 AIO01674.1 - 0.018 15.1 5.7 12 6.5 0.1 4.6 4 0 0 4 4 4 0 Leucine rich repeat LRR_4 PF12799.2 AIO01675.1 - 2.6e-15 55.6 8.0 0.00051 19.5 1.2 7.3 4 3 4 8 8 8 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 AIO01675.1 - 5.3e-13 48.5 5.5 8.6e-05 22.2 0.1 5.7 4 2 2 6 6 6 4 Leucine rich repeat LRR_1 PF00560.28 AIO01675.1 - 1.5e-08 33.4 0.8 0.63 10.2 0.1 8.6 9 0 0 9 9 9 1 Leucine Rich Repeat LRRNT_2 PF08263.7 AIO01675.1 - 0.052 13.5 0.4 0.052 13.5 0.3 3.2 3 0 0 3 3 3 0 Leucine rich repeat N-terminal domain LRR_6 PF13516.1 AIO01675.1 - 1.5 9.1 12.2 13 6.2 0.3 6.5 7 1 0 7 7 7 0 Leucine Rich repeat LRR_7 PF13504.1 AIO01675.1 - 2.2 8.8 11.9 12 6.6 0.2 6.5 7 1 0 7 7 7 0 Leucine rich repeat PIP5K PF01504.13 AIO01677.1 - 2e-59 200.7 0.0 3.7e-59 199.8 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase WD40 PF00400.27 AIO01678.1 - 1e-11 44.2 25.8 3.2e-06 26.7 1.5 7.1 8 0 0 8 8 8 4 WD domain, G-beta repeat Snf7 PF03357.16 AIO01679.1 - 3.8e-40 137.0 19.5 4.4e-40 136.8 13.5 1.0 1 0 0 1 1 1 1 Snf7 WEMBL PF05701.6 AIO01679.1 - 0.0017 16.9 8.0 0.0021 16.6 5.5 1.1 1 0 0 1 1 1 1 Weak chloroplast movement under blue light Ndr PF03096.9 AIO01679.1 - 0.087 11.2 2.8 0.11 10.9 1.9 1.1 1 0 0 1 1 1 0 Ndr family NPV_P10 PF05531.7 AIO01679.1 - 0.088 13.0 9.9 0.038 14.2 2.9 2.7 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF2031 PF09592.5 AIO01679.1 - 0.55 9.3 6.8 0.46 9.5 4.1 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2031) IncA PF04156.9 AIO01679.1 - 0.84 9.1 14.2 0.37 10.3 1.8 2.1 1 1 1 2 2 2 0 IncA protein Activator_LAG-3 PF11498.3 AIO01679.1 - 2.1 7.0 18.6 2.5 6.7 12.9 1.1 1 0 0 1 1 1 0 Transcriptional activator LAG-3 Ribosomal_L18ae PF01775.12 AIO01681.1 - 4.1e-40 136.5 1.3 5.6e-40 136.0 0.9 1.2 1 0 0 1 1 1 1 Ribosomal L18ae/LX protein domain Nup35_RRM_2 PF14605.1 AIO01684.1 - 4.5e-12 45.5 0.0 6.9e-12 44.9 0.0 1.3 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif Glyco_hydro_32N PF00251.15 AIO01685.1 - 1.2e-56 192.4 7.5 2e-56 191.6 5.2 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 N-terminal domain Glyco_hydro_32C PF08244.7 AIO01685.1 - 8.2e-08 32.5 0.0 2.8e-05 24.3 0.0 2.6 2 0 0 2 2 2 2 Glycosyl hydrolases family 32 C terminal PAN_4 PF14295.1 AIO01685.1 - 4.9e-05 22.9 2.7 4.9e-05 22.9 1.9 1.9 2 0 0 2 2 2 1 PAN domain zf-RING_6 PF14835.1 AIO01686.1 - 0.041 13.6 8.8 0.019 14.7 3.5 2.2 2 0 0 2 2 2 0 zf-RING of BARD1-type protein zf-RING_UBOX PF13445.1 AIO01686.1 - 0.2 11.3 5.8 0.47 10.2 4.0 1.6 1 0 0 1 1 1 0 RING-type zinc-finger zf-C3HC4 PF00097.20 AIO01686.1 - 0.69 9.6 15.2 0.072 12.7 6.5 2.3 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 AIO01686.1 - 0.96 9.5 17.4 0.078 13.0 7.6 2.4 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) DUF1272 PF06906.6 AIO01686.1 - 3.3 7.6 9.0 2.9 7.8 4.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1272) zf-C3HC4_4 PF15227.1 AIO01686.1 - 4 7.4 15.5 0.059 13.2 5.5 1.9 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING TPR_12 PF13424.1 AIO01689.1 - 6.4e-68 224.6 34.9 1e-14 54.1 1.1 8.1 6 2 2 8 8 8 8 Tetratricopeptide repeat TPR_10 PF13374.1 AIO01689.1 - 1.6e-38 129.5 24.6 3.1e-06 26.9 0.1 11.3 11 0 0 11 11 11 8 Tetratricopeptide repeat TPR_11 PF13414.1 AIO01689.1 - 4e-28 96.8 38.6 3e-07 30.0 0.1 8.1 5 3 2 8 8 8 7 TPR repeat TPR_2 PF07719.12 AIO01689.1 - 8.5e-21 72.1 43.6 0.0044 16.8 0.1 12.4 12 1 0 12 12 12 6 Tetratricopeptide repeat TPR_1 PF00515.23 AIO01689.1 - 1e-19 69.2 40.7 4.1e-05 22.9 0.0 12.2 13 0 0 13 13 13 6 Tetratricopeptide repeat TPR_8 PF13181.1 AIO01689.1 - 2.6e-16 58.1 28.3 0.021 14.5 0.0 10.9 12 0 0 12 12 12 6 Tetratricopeptide repeat TPR_16 PF13432.1 AIO01689.1 - 4.9e-16 58.9 28.7 0.003 18.1 0.3 8.9 7 2 1 9 9 9 5 Tetratricopeptide repeat TPR_7 PF13176.1 AIO01689.1 - 4.5e-15 54.1 22.2 0.0027 17.3 0.0 10.1 12 0 0 12 12 12 4 Tetratricopeptide repeat TPR_14 PF13428.1 AIO01689.1 - 4.4e-11 42.3 28.7 0.61 10.8 0.0 11.5 8 2 4 12 12 12 1 Tetratricopeptide repeat Apc3 PF12895.2 AIO01689.1 - 7.8e-08 32.3 34.1 0.00011 22.3 1.6 6.0 3 1 2 6 6 6 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.1 AIO01689.1 - 6.2e-06 26.4 27.1 0.046 14.0 0.2 7.6 6 1 2 8 8 8 2 Tetratricopeptide repeat SHNi-TPR PF10516.4 AIO01689.1 - 0.012 14.8 0.0 19 4.5 0.0 4.2 4 0 0 4 4 4 0 SHNi-TPR ATP-synt_D PF01813.12 AIO01690.1 - 8.8e-75 250.5 1.3 1.5e-74 249.8 0.9 1.3 1 0 0 1 1 1 1 ATP synthase subunit D Exo_endo_phos PF03372.18 AIO01691.1 - 6.4e-09 36.1 0.1 8.6e-09 35.6 0.1 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family SET PF00856.23 AIO01693.1 - 3.4e-11 43.6 1.2 0.009 16.3 0.0 3.7 3 0 0 3 3 3 3 SET domain FHA PF00498.21 AIO01694.1 - 0.0042 17.1 0.0 0.011 15.7 0.0 1.7 2 0 0 2 2 2 1 FHA domain PA28_beta PF02252.13 AIO01695.1 - 7.9e-07 28.6 0.0 0.002 17.5 0.0 2.2 2 0 0 2 2 2 2 Proteasome activator pa28 beta subunit CBS PF00571.23 AIO01696.1 - 6.2e-17 61.1 0.4 0.00014 21.5 0.0 4.3 4 0 0 4 4 4 4 CBS domain RrnaAD PF00398.15 AIO01697.1 - 3.2e-28 98.5 0.0 2e-27 95.8 0.0 1.8 1 1 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_12 PF08242.7 AIO01697.1 - 0.00064 20.1 0.0 0.0016 18.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain DOT1 PF08123.8 AIO01697.1 - 0.12 11.6 0.0 0.19 10.9 0.0 1.3 1 0 0 1 1 1 0 Histone methylation protein DOT1 Actin PF00022.14 AIO01698.1 - 1.8e-59 201.1 0.0 4.2e-47 160.4 0.0 2.0 2 0 0 2 2 2 2 Actin Aminotran_1_2 PF00155.16 AIO01701.1 - 1.3e-66 225.0 0.0 1.5e-66 224.8 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II FAD_binding_2 PF00890.19 AIO01702.1 - 5.6e-85 285.6 0.1 8.1e-85 285.1 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain ApbE PF02424.10 AIO01702.1 - 3.9e-54 183.6 0.0 1.3e-53 181.8 0.0 1.8 1 1 0 1 1 1 1 ApbE family NAD_binding_1 PF00175.16 AIO01702.1 - 3.3e-15 56.5 0.0 7.2e-15 55.5 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain DAO PF01266.19 AIO01702.1 - 6.1e-11 41.8 3.4 4.7e-10 38.8 2.2 2.1 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_oxidored PF12831.2 AIO01702.1 - 2.1e-10 40.2 6.1 6.7e-10 38.6 4.0 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 AIO01702.1 - 1.8e-09 37.7 0.4 1.6e-05 24.9 0.4 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_6 PF00970.19 AIO01702.1 - 2.3e-09 37.2 0.0 5.3e-09 36.0 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain GIDA PF01134.17 AIO01702.1 - 2e-06 26.9 5.7 1.4e-05 24.1 3.6 2.3 2 0 0 2 2 2 1 Glucose inhibited division protein A NAD_binding_8 PF13450.1 AIO01702.1 - 2.4e-06 27.4 4.0 3.7e-06 26.8 1.5 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 AIO01702.1 - 6.8e-05 23.0 1.0 0.0017 18.4 0.7 2.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 AIO01702.1 - 0.00015 20.3 4.7 0.00084 17.9 2.8 2.3 2 0 0 2 2 2 1 HI0933-like protein NAD_binding_6 PF08030.7 AIO01702.1 - 0.0033 17.3 0.0 0.043 13.7 0.0 2.3 2 0 0 2 2 2 1 Ferric reductase NAD binding domain AlaDh_PNT_C PF01262.16 AIO01702.1 - 0.0036 16.8 1.3 0.0078 15.8 0.9 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox PF00070.22 AIO01702.1 - 0.0057 17.0 3.4 0.0065 16.8 1.2 2.0 2 0 0 2 2 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 AIO01702.1 - 0.17 10.7 1.9 0.32 9.8 1.3 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein FAD_binding_3 PF01494.14 AIO01702.1 - 0.23 10.4 2.0 0.41 9.6 1.4 1.3 1 0 0 1 1 1 0 FAD binding domain DUF2838 PF10998.3 AIO01704.1 - 3.9e-12 46.0 10.5 1.4e-09 37.8 5.0 3.5 4 0 0 4 4 4 2 Protein of unknown function (DUF2838) Telomere_reg-2 PF10193.4 AIO01706.1 - 0.0084 16.3 0.0 0.092 13.0 0.0 2.7 3 0 0 3 3 3 1 Telomere length regulation protein Arabinose_Isome PF02610.10 AIO01708.1 - 0.074 12.0 0.2 0.13 11.2 0.1 1.3 1 0 0 1 1 1 0 L-arabinose isomerase COX6B PF02297.12 AIO01708.1 - 0.083 12.9 0.6 4.5 7.3 0.2 2.3 2 0 0 2 2 2 0 Cytochrome oxidase c subunit VIb tRNA-synt_2c PF01411.14 AIO01709.1 - 0.94 7.6 12.1 0.045 12.0 4.0 1.7 1 1 1 2 2 2 0 tRNA synthetases class II (A) DUF4355 PF14265.1 AIO01712.1 - 8 6.4 10.1 31 4.5 7.0 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4355) PSP1 PF04468.7 AIO01714.1 - 6e-27 93.4 0.3 1.3e-26 92.3 0.2 1.6 1 0 0 1 1 1 1 PSP1 C-terminal conserved region Cupin_8 PF13621.1 AIO01715.1 - 0.083 12.3 0.0 0.33 10.4 0.0 1.9 2 0 0 2 2 2 0 Cupin-like domain cIII PF08134.6 AIO01715.1 - 0.13 11.9 0.4 0.47 10.0 0.1 2.1 2 0 0 2 2 2 0 cIII protein family Pkinase PF00069.20 AIO01717.1 - 7e-31 107.3 0.0 8.7e-31 107.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AIO01717.1 - 6.1e-15 55.0 0.0 8.3e-15 54.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 AIO01717.1 - 1.6e-06 28.0 0.0 3e-06 27.1 0.0 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.4 AIO01717.1 - 0.0012 18.2 0.0 0.002 17.4 0.0 1.3 1 0 0 1 1 1 1 PhoP regulatory network protein YrbL Kdo PF06293.9 AIO01717.1 - 0.019 14.0 0.1 0.03 13.3 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.20 AIO01718.1 - 2.1e-35 122.1 0.0 2.5e-35 121.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AIO01718.1 - 3.9e-13 49.0 0.0 5.1e-13 48.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 AIO01718.1 - 0.00015 21.6 0.0 0.00044 20.0 0.0 1.8 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 AIO01718.1 - 0.0068 15.4 0.0 0.011 14.8 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 AIO01718.1 - 0.12 11.6 0.0 0.2 11.0 0.0 1.3 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL zf-CCCH PF00642.19 AIO01719.1 - 0.00011 21.8 6.1 0.00021 20.8 4.2 1.5 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Cupin_5 PF06172.6 AIO01720.1 - 5e-37 126.9 0.0 8.7e-22 77.5 0.0 2.1 2 0 0 2 2 2 2 Cupin superfamily (DUF985) zf-CCCH PF00642.19 AIO01721.1 - 6.6e-07 28.8 1.0 6.6e-07 28.8 0.7 2.7 3 0 0 3 3 3 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Fra10Ac1 PF09725.4 AIO01721.1 - 0.017 15.2 0.1 0.04 14.0 0.0 1.7 1 0 0 1 1 1 0 Folate-sensitive fragile site protein Fra10Ac1 RP-C_C PF11800.3 AIO01721.1 - 0.045 13.4 2.0 0.076 12.7 1.4 1.3 1 0 0 1 1 1 0 Replication protein C C-terminal region Pkinase PF00069.20 AIO01722.1 - 7e-65 218.7 0.1 1.2e-64 218.0 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AIO01722.1 - 1.6e-22 79.8 0.1 1.3e-21 76.8 0.1 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 AIO01722.1 - 2e-06 26.9 0.2 0.12 11.2 0.1 3.0 2 1 1 3 3 3 2 Kinase-like Kdo PF06293.9 AIO01722.1 - 0.0024 16.9 0.0 0.0043 16.1 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 AIO01722.1 - 0.057 12.7 0.3 0.27 10.5 0.1 2.0 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL Kri1_C PF12936.2 AIO01725.1 - 1.9e-22 79.0 0.1 1e-21 76.6 0.1 2.4 1 0 0 1 1 1 1 KRI1-like family C-terminal Kri1 PF05178.7 AIO01725.1 - 3.3e-21 75.4 9.5 3.3e-21 75.4 6.6 4.8 5 1 0 5 5 5 1 KRI1-like family MEF2_binding PF09047.5 AIO01725.1 - 1.4 8.5 7.9 1.5 8.5 0.2 3.0 2 0 0 2 2 2 0 MEF2 binding Rdx PF10262.4 AIO01727.1 - 1.3e-16 60.3 0.0 3e-16 59.1 0.0 1.6 2 0 0 2 2 2 1 Rdx family PPO1_KFDV PF12143.3 AIO01727.1 - 0.14 12.0 1.1 0.25 11.2 0.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF_B2219) Lysis_col PF02402.11 AIO01727.1 - 0.18 11.3 0.1 0.18 11.3 0.1 2.1 2 0 0 2 2 2 0 Lysis protein STT3 PF02516.9 AIO01728.1 - 1.4e-21 77.0 10.1 1.7e-21 76.7 7.0 1.1 1 0 0 1 1 1 1 Oligosaccharyl transferase STT3 subunit STT3 PF02516.9 AIO01729.1 - 0.0073 15.3 0.2 0.075 11.9 0.1 2.0 1 1 1 2 2 2 2 Oligosaccharyl transferase STT3 subunit DUF1358 PF07096.6 AIO01729.1 - 0.079 12.6 0.4 0.14 11.8 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1358) Rhodanese PF00581.15 AIO01730.1 - 1.9e-10 41.0 0.0 3.7e-10 40.1 0.0 1.5 1 0 0 1 1 1 1 Rhodanese-like domain ApbE PF02424.10 AIO01731.1 - 5.2e-68 229.0 0.0 7.7e-68 228.5 0.0 1.3 1 0 0 1 1 1 1 ApbE family FAD_binding_2 PF00890.19 AIO01731.1 - 2.1e-30 105.9 0.5 3.4e-30 105.2 0.3 1.3 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.2 AIO01731.1 - 1.1e-10 41.1 0.4 2.1e-10 40.2 0.3 1.6 1 0 0 1 1 1 1 FAD dependent oxidoreductase DAO PF01266.19 AIO01731.1 - 1.3e-07 30.8 0.9 1.3e-07 30.8 0.7 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 AIO01731.1 - 1.1e-06 28.5 2.7 3.4e-06 26.9 1.0 2.5 2 1 1 3 3 3 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 AIO01731.1 - 6.2e-06 26.2 1.9 1.7e-05 24.8 1.3 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 AIO01731.1 - 1.1e-05 24.5 5.1 1.4e-05 24.1 2.6 1.8 2 0 0 2 2 2 1 Glucose inhibited division protein A HI0933_like PF03486.9 AIO01731.1 - 0.00023 19.7 2.9 0.0004 18.9 2.0 1.4 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox PF00070.22 AIO01731.1 - 0.00043 20.6 0.8 0.00043 20.6 0.5 2.6 3 0 0 3 3 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 AIO01731.1 - 0.0017 17.4 0.7 0.0029 16.7 0.5 1.3 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.12 AIO01731.1 - 0.0023 17.0 2.2 0.011 14.7 0.7 2.5 2 0 0 2 2 2 1 Thi4 family AlaDh_PNT_C PF01262.16 AIO01731.1 - 0.0024 17.4 0.3 0.0056 16.2 0.2 1.6 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox_3 PF13738.1 AIO01731.1 - 0.023 14.7 1.4 0.04 13.9 0.3 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase P22_Tail-4 PF11650.3 AIO01731.1 - 0.024 14.1 0.0 0.046 13.2 0.0 1.4 1 0 0 1 1 1 0 P22 tail accessory factor Lycopene_cycl PF05834.7 AIO01731.1 - 0.057 12.3 1.2 0.09 11.6 0.8 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein NAD_binding_1 PF00175.16 AIO01732.1 - 3.5e-18 66.1 0.0 4.9e-18 65.6 0.0 1.2 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 AIO01732.1 - 3.1e-09 36.8 0.0 5.1e-09 36.1 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.7 AIO01732.1 - 1.9e-08 34.3 0.0 0.0002 21.2 0.0 2.3 2 0 0 2 2 2 2 Ferric reductase NAD binding domain HA2 PF04408.18 AIO01733.1 - 4e-22 78.1 0.1 9.8e-22 76.9 0.0 1.7 2 0 0 2 2 2 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 AIO01733.1 - 1.5e-18 66.6 0.1 3.5e-18 65.4 0.0 1.7 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.26 AIO01733.1 - 7.8e-14 51.2 0.0 2.1e-13 49.9 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 AIO01733.1 - 5.4e-09 35.7 0.2 2.2e-08 33.8 0.1 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_22 PF13401.1 AIO01733.1 - 3.4e-06 27.2 0.0 7.7e-06 26.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain T2SE PF00437.15 AIO01733.1 - 0.00011 21.1 0.0 0.00023 20.1 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_19 PF13245.1 AIO01733.1 - 0.0023 17.6 0.2 0.011 15.5 0.0 2.1 2 0 0 2 2 2 1 Part of AAA domain ResIII PF04851.10 AIO01733.1 - 0.02 14.7 0.1 4.8 6.9 0.0 2.4 1 1 0 2 2 2 0 Type III restriction enzyme, res subunit ABC_tran PF00005.22 AIO01733.1 - 0.032 14.5 0.2 0.91 9.8 0.1 2.4 1 1 0 2 2 2 0 ABC transporter AAA_30 PF13604.1 AIO01733.1 - 0.043 13.3 0.0 0.17 11.4 0.0 1.9 2 0 0 2 2 2 0 AAA domain Sigma54_activ_2 PF14532.1 AIO01733.1 - 0.046 13.7 0.0 0.25 11.3 0.0 2.2 2 0 0 2 2 2 0 Sigma-54 interaction domain Sigma54_activat PF00158.21 AIO01733.1 - 0.058 12.8 0.0 0.49 9.8 0.0 2.1 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_29 PF13555.1 AIO01733.1 - 0.064 12.7 0.0 0.14 11.6 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_11 PF13086.1 AIO01733.1 - 0.079 12.5 0.0 0.25 10.9 0.0 1.8 2 0 0 2 2 2 0 AAA domain Armet PF10208.4 AIO01734.1 - 2.1e-08 33.9 0.1 3.6e-08 33.2 0.0 1.3 1 0 0 1 1 1 1 Degradation arginine-rich protein for mis-folding SAP PF02037.22 AIO01734.1 - 0.0023 17.4 0.1 0.0049 16.3 0.0 1.6 1 0 0 1 1 1 1 SAP domain adh_short PF00106.20 AIO01735.1 - 3.6e-27 95.3 0.0 4.7e-27 94.9 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 AIO01735.1 - 7.8e-15 55.3 0.3 1e-14 54.8 0.2 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 AIO01735.1 - 5.6e-11 42.4 0.0 7.2e-11 42.0 0.0 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 AIO01735.1 - 4e-05 23.6 0.0 6.6e-05 23.0 0.0 1.3 1 1 0 1 1 1 1 NADH(P)-binding DUF871 PF05913.6 AIO01735.1 - 0.00058 18.8 0.0 0.00075 18.4 0.0 1.1 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF871) Epimerase PF01370.16 AIO01735.1 - 0.012 15.0 0.3 0.032 13.6 0.2 1.7 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family QRPTase_C PF01729.14 AIO01735.1 - 0.067 12.7 0.0 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 Quinolinate phosphoribosyl transferase, C-terminal domain Polysacc_synt_2 PF02719.10 AIO01735.1 - 0.072 11.9 1.0 0.099 11.5 0.1 1.6 2 1 0 2 2 2 0 Polysaccharide biosynthesis protein DUF1161 PF06649.7 AIO01735.1 - 0.25 11.3 1.6 4.4 7.3 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1161) adh_short PF00106.20 AIO01736.1 - 4.4e-20 72.2 0.3 2.2e-19 69.9 0.2 1.9 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 AIO01736.1 - 9.5e-07 28.8 0.0 1.3e-06 28.3 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 AIO01736.1 - 1.6e-06 27.8 0.0 3.4e-06 26.8 0.0 1.5 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 AIO01736.1 - 6.5e-06 25.7 0.0 1.3e-05 24.7 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 AIO01736.1 - 0.0002 21.3 0.1 0.0018 18.3 0.1 2.0 1 1 0 1 1 1 1 NADH(P)-binding TIR-like PF10137.4 AIO01736.1 - 0.1 12.2 0.0 0.17 11.5 0.0 1.3 1 0 0 1 1 1 0 Predicted nucleotide-binding protein containing TIR-like domain Glutaredoxin PF00462.19 AIO01738.1 - 6.7e-18 64.4 2.9 1.4e-13 50.5 0.1 3.1 3 0 0 3 3 3 2 Glutaredoxin Thioredoxin PF00085.15 AIO01738.1 - 6.9e-15 54.6 0.3 1.3e-14 53.7 0.2 1.5 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.1 AIO01738.1 - 0.00041 20.4 0.1 0.0011 19.0 0.0 1.7 2 0 0 2 2 2 1 Thioredoxin-like Thioredoxin_7 PF13899.1 AIO01738.1 - 0.00063 19.7 0.1 0.0011 18.9 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin-like Redoxin PF08534.5 AIO01738.1 - 0.014 14.9 0.1 0.026 14.0 0.1 1.5 1 0 0 1 1 1 0 Redoxin Thioredoxin_3 PF13192.1 AIO01738.1 - 0.014 15.1 0.3 0.14 12.0 0.1 2.3 2 1 0 2 2 2 0 Thioredoxin domain Thioredoxin_2 PF13098.1 AIO01738.1 - 0.04 14.1 0.6 0.058 13.5 0.2 1.7 1 1 0 1 1 1 0 Thioredoxin-like domain AhpC-TSA PF00578.16 AIO01738.1 - 0.05 13.2 0.0 0.07 12.8 0.0 1.4 1 0 0 1 1 1 0 AhpC/TSA family Thioredoxin_6 PF13848.1 AIO01738.1 - 0.088 12.6 0.0 0.18 11.5 0.0 1.5 1 0 0 1 1 1 0 Thioredoxin-like domain AAA PF00004.24 AIO01739.1 - 5.8e-36 123.5 0.0 1.3e-35 122.4 0.0 1.6 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 AIO01739.1 - 3.8e-08 34.1 0.1 1.5e-07 32.2 0.0 2.1 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.1 AIO01739.1 - 8.7e-08 32.3 0.1 6.2e-06 26.3 0.0 2.4 1 1 1 2 2 2 1 AAA ATPase domain AAA_5 PF07728.9 AIO01739.1 - 1.1e-07 31.6 0.0 3.1e-07 30.2 0.0 1.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.7 AIO01739.1 - 3.7e-07 29.4 0.0 9.8e-07 28.0 0.0 1.7 1 1 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 AIO01739.1 - 1.2e-06 28.7 0.0 0.00014 21.9 0.0 2.5 1 1 0 1 1 1 1 AAA domain TIP49 PF06068.8 AIO01739.1 - 1.8e-06 26.9 0.0 7.8e-06 24.8 0.0 1.9 1 1 1 2 2 2 1 TIP49 C-terminus AAA_33 PF13671.1 AIO01739.1 - 8e-06 25.7 0.0 1.6e-05 24.7 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 AIO01739.1 - 1.8e-05 25.0 0.0 3e-05 24.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 AIO01739.1 - 3.7e-05 22.9 0.0 0.00015 20.9 0.0 1.9 2 0 0 2 2 2 1 Zeta toxin AAA_14 PF13173.1 AIO01739.1 - 8e-05 22.5 0.0 0.00014 21.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.12 AIO01739.1 - 0.00019 20.9 0.0 0.00032 20.1 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_19 PF13245.1 AIO01739.1 - 0.00031 20.4 0.4 0.002 17.8 0.2 2.3 1 1 0 1 1 1 1 Part of AAA domain SKI PF01202.17 AIO01739.1 - 0.00035 20.4 0.0 0.0013 18.6 0.0 1.9 2 0 0 2 2 2 1 Shikimate kinase RNA_helicase PF00910.17 AIO01739.1 - 0.0004 20.5 0.0 0.00084 19.4 0.0 1.6 1 1 0 1 1 1 1 RNA helicase AAA_28 PF13521.1 AIO01739.1 - 0.0018 18.2 0.1 0.0041 17.0 0.0 1.7 2 0 0 2 2 1 1 AAA domain Sigma54_activ_2 PF14532.1 AIO01739.1 - 0.0019 18.2 0.0 0.0096 15.9 0.0 2.2 2 2 0 2 2 2 1 Sigma-54 interaction domain AAA_3 PF07726.6 AIO01739.1 - 0.0027 17.2 0.0 0.0092 15.5 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.16 AIO01739.1 - 0.0027 16.8 0.0 0.0055 15.8 0.0 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_24 PF13479.1 AIO01739.1 - 0.0043 16.6 0.3 0.01 15.4 0.0 1.7 2 0 0 2 2 1 1 AAA domain AAA_25 PF13481.1 AIO01739.1 - 0.0045 16.4 1.0 0.066 12.6 0.1 2.3 1 1 1 2 2 2 1 AAA domain NACHT PF05729.7 AIO01739.1 - 0.0056 16.3 0.0 0.015 14.9 0.0 1.7 1 1 0 1 1 1 1 NACHT domain AAA_2 PF07724.9 AIO01739.1 - 0.0065 16.3 0.0 0.013 15.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) Sigma54_activat PF00158.21 AIO01739.1 - 0.0093 15.4 0.0 0.035 13.5 0.0 1.9 2 0 0 2 2 2 1 Sigma-54 interaction domain Parvo_NS1 PF01057.12 AIO01739.1 - 0.017 13.9 0.0 0.031 13.1 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_11 PF13086.1 AIO01739.1 - 0.021 14.3 0.0 0.034 13.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain UPF0079 PF02367.12 AIO01739.1 - 0.022 14.3 0.0 0.045 13.3 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 AAA_29 PF13555.1 AIO01739.1 - 0.028 13.9 0.0 0.072 12.6 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain PhoH PF02562.11 AIO01739.1 - 0.03 13.5 0.0 0.058 12.6 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein DUF815 PF05673.8 AIO01739.1 - 0.032 13.1 0.0 0.083 11.7 0.0 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF815) Rad17 PF03215.10 AIO01739.1 - 0.044 12.4 0.0 0.061 12.0 0.0 1.2 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein DUF2075 PF09848.4 AIO01739.1 - 0.055 12.4 0.0 0.083 11.8 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) ABC_tran PF00005.22 AIO01739.1 - 0.06 13.6 0.1 1.4 9.2 0.0 2.5 1 1 2 3 3 2 0 ABC transporter PPV_E1_C PF00519.12 AIO01739.1 - 0.075 11.6 0.0 0.11 11.0 0.0 1.2 1 0 0 1 1 1 0 Papillomavirus helicase ResIII PF04851.10 AIO01739.1 - 0.094 12.5 0.0 0.13 12.0 0.0 1.3 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_21 PF13304.1 AIO01739.1 - 0.2 11.6 0.1 17 5.2 0.0 2.3 1 1 1 2 2 2 0 AAA domain fn2 PF00040.14 AIO01740.1 - 1.1 9.2 4.1 4 7.5 0.2 2.9 2 1 1 3 3 3 0 Fibronectin type II domain 2OG-FeII_Oxy_2 PF13532.1 AIO01741.1 - 4.6e-11 42.9 0.0 7.2e-11 42.2 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 AIO01741.1 - 5.1e-06 26.7 0.1 7.4e-05 22.9 0.0 2.2 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily UQ_con PF00179.21 AIO01743.1 - 5.2e-54 181.4 0.0 5.8e-54 181.3 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 AIO01743.1 - 0.0019 18.0 0.0 0.0022 17.8 0.0 1.2 1 0 0 1 1 1 1 RWD domain Prok-E2_B PF14461.1 AIO01743.1 - 0.004 16.9 0.0 0.0047 16.6 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.8 AIO01743.1 - 0.097 12.3 0.0 0.14 11.8 0.0 1.4 1 0 0 1 1 1 0 UEV domain Histone PF00125.19 AIO01744.1 - 5.9e-13 48.7 0.5 7.2e-13 48.4 0.4 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 AIO01744.1 - 0.00045 20.2 0.4 0.00062 19.7 0.0 1.4 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TAF PF02969.12 AIO01744.1 - 0.00092 19.1 0.1 0.0015 18.4 0.1 1.4 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) Bromo_TP PF07524.8 AIO01744.1 - 0.0034 17.0 0.0 0.0042 16.7 0.0 1.2 1 0 0 1 1 1 1 Bromodomain associated TFIID-31kDa PF02291.10 AIO01744.1 - 0.0048 16.6 0.0 0.0048 16.6 0.0 1.2 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit DUF29 PF01724.11 AIO01745.1 - 0.055 13.3 0.6 0.13 12.0 0.4 1.6 1 0 0 1 1 1 0 Domain of unknown function DUF29 Thioredoxin PF00085.15 AIO01746.1 - 8.7e-14 51.0 0.0 2.2e-13 49.7 0.0 1.7 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_6 PF13848.1 AIO01746.1 - 0.0013 18.5 0.0 1 9.1 0.0 2.6 2 1 0 2 2 2 2 Thioredoxin-like domain Thioredoxin_8 PF13905.1 AIO01746.1 - 0.033 14.3 0.1 0.19 11.8 0.1 2.4 2 1 0 2 2 2 0 Thioredoxin-like Thioredoxin_7 PF13899.1 AIO01746.1 - 0.087 12.8 0.1 0.33 11.0 0.0 2.0 1 0 0 1 1 1 0 Thioredoxin-like Thioredoxin_2 PF13098.1 AIO01746.1 - 0.16 12.1 0.2 1.1 9.4 0.1 2.4 2 1 0 2 2 2 0 Thioredoxin-like domain Endonuc_subdom PF09062.5 AIO01746.1 - 0.17 12.6 0.4 38 5.1 0.0 2.5 2 0 0 2 2 2 0 PI-PfuI Endonuclease subdomain DUF1028 PF06267.7 AIO01747.1 - 0.027 13.9 0.2 0.042 13.2 0.1 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF1028) zf-CDGSH PF09360.5 AIO01750.1 - 2.6e-25 87.9 10.3 3.7e-14 52.2 1.5 2.2 2 0 0 2 2 2 2 Iron-binding zinc finger CDGSH type Peptidase_M16 PF00675.15 AIO01751.1 - 1.7e-27 96.0 0.0 2.8e-27 95.3 0.0 1.3 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 AIO01751.1 - 1.2e-15 57.6 0.0 2.2e-15 56.7 0.0 1.5 1 0 0 1 1 1 1 Peptidase M16 inactive domain OTU PF02338.14 AIO01752.1 - 3.1e-15 56.8 0.1 5.6e-15 55.9 0.1 1.4 1 0 0 1 1 1 1 OTU-like cysteine protease zf-RanBP PF00641.13 AIO01752.1 - 0.00011 21.2 1.8 0.00011 21.2 1.3 5.0 5 0 0 5 5 5 2 Zn-finger in Ran binding protein and others Peptidase_C65 PF10275.4 AIO01752.1 - 0.00019 20.8 0.0 0.51 9.6 0.0 2.3 1 1 1 2 2 2 2 Peptidase C65 Otubain RRN7 PF11781.3 AIO01752.1 - 0.009 15.4 2.9 0.009 15.4 2.0 3.3 4 0 0 4 4 4 1 RNA polymerase I-specific transcription initiation factor Rrn7 zf-tcix PF14952.1 AIO01752.1 - 0.031 13.5 0.2 0.031 13.5 0.1 3.8 3 0 0 3 3 3 0 Putative treble-clef, zinc-finger, Zn-binding DZR PF12773.2 AIO01752.1 - 0.34 10.7 28.0 0.51 10.2 4.0 3.9 3 1 0 3 3 3 0 Double zinc ribbon zf-ribbon_3 PF13248.1 AIO01752.1 - 5.2 6.4 19.8 0.2 10.8 0.3 3.6 3 0 0 3 3 3 0 zinc-ribbon domain RRM_1 PF00076.17 AIO01753.1 - 1.4e-06 27.7 0.0 0.06 12.9 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 AIO01753.1 - 2.7e-05 24.0 0.0 7.2e-05 22.6 0.0 1.7 1 1 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 AIO01753.1 - 3.2e-05 23.6 0.0 0.00017 21.3 0.0 2.1 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) His_Phos_1 PF00300.17 AIO01753.1 - 0.013 15.5 1.2 0.02 14.9 0.8 1.2 1 0 0 1 1 1 0 Histidine phosphatase superfamily (branch 1) tRNA-synt_2b PF00587.20 AIO01754.1 - 5.4e-44 149.8 0.0 1.1e-43 148.7 0.0 1.5 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 AIO01754.1 - 8e-18 64.1 0.1 1.9e-17 62.9 0.1 1.7 1 0 0 1 1 1 1 Anticodon binding domain TGS PF02824.16 AIO01754.1 - 7.1e-14 51.3 0.0 1.6e-13 50.2 0.0 1.6 1 0 0 1 1 1 1 TGS domain tRNA_SAD PF07973.9 AIO01754.1 - 3.5e-11 42.8 0.0 6.1e-11 42.0 0.0 1.4 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain Stm1_N PF09598.5 AIO01754.1 - 1.9 9.2 5.3 4.6 8.0 3.7 1.7 1 0 0 1 1 1 0 Stm1 TPR_11 PF13414.1 AIO01755.1 - 8.9e-24 82.9 12.8 4.2e-11 42.3 1.0 5.1 2 2 3 5 5 5 5 TPR repeat TPR_1 PF00515.23 AIO01755.1 - 8.2e-20 69.5 4.7 1.3e-05 24.5 0.1 6.1 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_17 PF13431.1 AIO01755.1 - 1.8e-18 65.1 7.9 0.00014 21.7 0.6 5.7 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_2 PF07719.12 AIO01755.1 - 3.4e-18 64.0 7.0 3.1e-05 23.5 0.0 6.6 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_16 PF13432.1 AIO01755.1 - 1.2e-17 64.0 11.4 7.7e-09 36.0 0.4 4.7 2 2 3 5 5 5 4 Tetratricopeptide repeat TPR_14 PF13428.1 AIO01755.1 - 4.2e-14 51.7 13.9 0.00045 20.5 0.0 7.0 3 2 4 7 7 6 4 Tetratricopeptide repeat TPR_19 PF14559.1 AIO01755.1 - 4.4e-12 46.1 7.9 8.6e-06 26.0 0.1 4.9 2 2 3 5 5 5 4 Tetratricopeptide repeat TPR_12 PF13424.1 AIO01755.1 - 2e-11 43.6 2.4 4.6e-07 29.6 0.0 3.2 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.1 AIO01755.1 - 7.3e-10 37.9 2.4 0.011 15.4 0.0 5.6 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_7 PF13176.1 AIO01755.1 - 4.6e-07 29.1 0.2 1.5 8.7 0.0 5.5 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_9 PF13371.1 AIO01755.1 - 0.00024 20.8 1.3 0.0032 17.3 0.0 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_10 PF13374.1 AIO01755.1 - 0.0094 15.8 6.3 4.5 7.3 0.0 4.2 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_6 PF13174.1 AIO01755.1 - 0.012 16.0 9.4 15 6.3 0.0 5.9 6 0 0 6 6 5 0 Tetratricopeptide repeat Apc3 PF12895.2 AIO01755.1 - 0.046 13.8 1.6 0.15 12.2 0.1 2.5 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 BTAD PF03704.12 AIO01755.1 - 0.12 12.6 10.5 0.19 12.0 0.0 3.8 3 1 1 4 4 4 0 Bacterial transcriptional activator domain TPR_20 PF14561.1 AIO01755.1 - 0.65 10.1 20.9 1.4 9.0 0.1 5.1 4 1 2 6 6 4 0 Tetratricopeptide repeat Ribosomal_L2_C PF03947.13 AIO01756.1 - 4.6e-40 136.4 2.0 6.2e-40 136.0 0.8 1.6 2 0 0 2 2 2 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.18 AIO01756.1 - 3.5e-13 49.3 0.0 1.2e-12 47.6 0.0 1.9 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain Apo-CIII PF05778.7 AIO01757.1 - 0.037 13.3 0.0 0.14 11.5 0.0 1.9 1 0 0 1 1 1 0 Apolipoprotein CIII (Apo-CIII) DUF4211 PF13926.1 AIO01757.1 - 0.13 11.6 0.0 0.3 10.4 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4211) TPR_MLP1_2 PF07926.7 AIO01758.1 - 3.5e-08 33.2 33.5 7.7e-05 22.4 0.0 5.4 3 2 2 5 5 5 2 TPR/MLP1/MLP2-like protein Choline_kinase PF01633.15 AIO01760.1 - 3.8e-31 108.3 0.0 3.7e-30 105.0 0.0 2.2 1 1 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.18 AIO01760.1 - 9.6e-10 38.5 0.0 6.8e-07 29.2 0.0 2.9 2 1 0 2 2 2 2 Phosphotransferase enzyme family Arginase PF00491.16 AIO01761.1 - 1.1e-70 238.1 0.0 1.3e-70 237.9 0.0 1.0 1 0 0 1 1 1 1 Arginase family zf-CCCH PF00642.19 AIO01763.1 - 4.9e-05 22.9 1.4 0.0001 21.9 1.0 1.6 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) NIF PF03031.13 AIO01763.1 - 0.0028 17.3 0.0 0.0057 16.3 0.0 1.4 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase CENP-U PF13097.1 AIO01763.1 - 0.035 14.0 0.3 0.035 14.0 0.2 2.0 2 0 0 2 2 2 0 CENP-A nucleosome associated complex (NAC) subunit Rieske PF00355.21 AIO01766.1 - 5.6e-15 54.7 0.0 9.7e-15 53.9 0.0 1.4 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Methyltransf_23 PF13489.1 AIO01769.1 - 8.3e-17 61.3 0.0 1.6e-16 60.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 AIO01769.1 - 4.3e-12 46.3 0.0 9.1e-12 45.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 AIO01769.1 - 4.7e-09 35.7 0.0 6.5e-09 35.2 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.7 AIO01769.1 - 1.5e-07 31.7 0.0 5.9e-07 29.8 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 AIO01769.1 - 1.4e-06 27.9 0.0 2.7e-06 27.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 AIO01769.1 - 0.00016 22.0 0.0 0.0003 21.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 AIO01769.1 - 0.00021 21.2 0.0 0.0018 18.2 0.0 2.3 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 AIO01769.1 - 0.03 14.9 0.0 0.063 13.8 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Peptidase_C14 PF00656.17 AIO01770.1 - 1.5e-49 168.9 0.0 1.9e-49 168.6 0.0 1.1 1 0 0 1 1 1 1 Caspase domain DUF2273 PF10031.4 AIO01771.1 - 0.0018 17.8 0.0 0.003 17.1 0.0 1.3 1 0 0 1 1 1 1 Small integral membrane protein (DUF2273) Baculo_gp64 PF03273.8 AIO01771.1 - 0.037 12.1 0.7 0.06 11.5 0.5 1.2 1 0 0 1 1 1 0 Baculovirus gp64 envelope glycoprotein family Cauli_AT PF03233.8 AIO01771.1 - 0.36 10.5 3.0 0.64 9.7 2.1 1.3 1 0 0 1 1 1 0 Aphid transmission protein Laminin_G_3 PF13385.1 AIO01774.1 - 1.3e-09 38.4 0.3 7e-09 36.1 0.0 2.3 2 0 0 2 2 2 1 Concanavalin A-like lectin/glucanases superfamily Ribosomal_L10 PF00466.15 AIO01774.1 - 0.063 13.2 0.4 0.85 9.5 0.1 2.7 3 0 0 3 3 3 0 Ribosomal protein L10 EF-hand_7 PF13499.1 AIO01775.1 - 0.0015 18.6 0.0 0.0031 17.6 0.0 1.5 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.1 AIO01775.1 - 0.049 13.5 0.0 25 5.0 0.0 3.0 3 0 0 3 3 3 0 EF-hand domain EF-hand_1 PF00036.27 AIO01775.1 - 0.12 11.7 0.0 1.6 8.2 0.0 2.3 2 0 0 2 2 2 0 EF hand Herpes_UL35 PF04496.7 AIO01776.1 - 0.0099 16.0 0.4 0.027 14.7 0.0 1.8 2 0 0 2 2 2 1 Herpesvirus UL35 family NfI_DNAbd_pre-N PF10524.4 AIO01776.1 - 0.078 12.5 2.3 0.71 9.5 0.2 2.5 2 0 0 2 2 2 0 Nuclear factor I protein pre-N-terminus Cortex-I_coil PF09304.5 AIO01777.1 - 0.0059 16.6 7.9 0.0059 16.6 5.5 7.3 2 2 5 8 8 8 2 Cortexillin I, coiled coil NYD-SP28_assoc PF14775.1 AIO01777.1 - 0.079 12.6 0.4 0.079 12.6 0.2 5.3 4 1 1 5 5 5 0 Sperm tail C-terminal domain MutL_C PF08676.6 AIO01778.1 - 1.6e-27 95.9 0.0 2.9e-27 95.0 0.0 1.4 1 0 0 1 1 1 1 MutL C terminal dimerisation domain DNA_mis_repair PF01119.14 AIO01778.1 - 8.7e-12 44.5 0.0 1.6e-11 43.7 0.0 1.4 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c PF02518.21 AIO01778.1 - 3.4e-06 26.7 0.0 1e-05 25.1 0.0 1.9 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.1 AIO01778.1 - 6.8e-06 25.7 0.0 1.9e-05 24.3 0.0 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase KOW PF00467.24 AIO01779.1 - 1.5e-06 27.6 0.5 4.2e-06 26.2 0.3 1.9 1 1 0 1 1 1 1 KOW motif SieB PF14163.1 AIO01780.1 - 0.14 11.7 0.7 0.24 10.9 0.5 1.4 1 0 0 1 1 1 0 Superinfection exclusion protein B LRR_4 PF12799.2 AIO01781.1 - 2.1e-15 55.9 9.2 3.8e-05 23.1 0.7 5.4 2 1 3 5 5 5 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 AIO01781.1 - 4.5e-12 45.5 15.6 6.6e-06 25.7 1.3 4.2 2 2 1 3 3 3 3 Leucine rich repeat LRR_1 PF00560.28 AIO01781.1 - 9.2e-10 37.1 12.4 1.5 9.1 0.0 7.5 6 1 0 6 6 6 4 Leucine Rich Repeat LRR_6 PF13516.1 AIO01781.1 - 2.8e-07 29.9 9.5 1.5 9.0 0.1 7.0 7 0 0 7 7 7 2 Leucine Rich repeat LRR_7 PF13504.1 AIO01781.1 - 3.7e-07 29.2 17.2 0.24 11.7 0.1 7.7 7 0 0 7 7 7 2 Leucine rich repeat Takusan PF04822.8 AIO01781.1 - 0.006 16.3 2.4 0.015 15.0 1.7 1.7 1 0 0 1 1 1 1 Takusan EzrA PF06160.7 AIO01781.1 - 0.01 14.0 6.5 0.013 13.6 4.5 1.1 1 0 0 1 1 1 1 Septation ring formation regulator, EzrA Clp_N PF02861.15 AIO01781.1 - 0.024 14.5 0.1 0.063 13.2 0.1 1.8 1 0 0 1 1 1 0 Clp amino terminal domain LRR_9 PF14580.1 AIO01781.1 - 0.068 12.7 1.2 4.7 6.7 0.0 2.7 2 1 1 3 3 3 0 Leucine-rich repeat Sec2p PF06428.6 AIO01781.1 - 0.6 9.9 13.1 1.8 8.4 2.2 2.7 1 1 1 2 2 2 0 GDP/GTP exchange factor Sec2p DivIVA PF05103.8 AIO01781.1 - 2.5 8.1 11.6 0.33 11.0 2.0 2.3 1 1 1 2 2 2 0 DivIVA protein RTC PF01137.16 AIO01782.1 - 4.7e-53 179.3 0.1 5.3e-53 179.1 0.0 1.0 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase RTC_insert PF05189.8 AIO01782.1 - 4.3e-26 90.9 0.1 6.7e-26 90.3 0.1 1.3 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase (RTC), insert domain Pro_isomerase PF00160.16 AIO01783.1 - 7.3e-13 49.0 0.0 1.3e-12 48.2 0.0 1.4 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Pkinase PF00069.20 AIO01784.1 - 3.2e-55 187.1 0.0 3.7e-55 186.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AIO01784.1 - 1.8e-18 66.5 0.0 2.5e-18 66.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 AIO01784.1 - 8.4e-06 25.6 0.0 0.00069 19.4 0.0 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kinase-like PF14531.1 AIO01784.1 - 0.0037 16.2 0.0 0.0059 15.6 0.0 1.3 1 0 0 1 1 1 1 Kinase-like UCH PF00443.24 AIO01785.1 - 1.7e-51 174.9 0.8 2.9e-51 174.1 0.6 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 AIO01785.1 - 1.4e-25 90.3 0.0 2.2e-25 89.7 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase USP7_ICP0_bdg PF12436.3 AIO01785.1 - 1.8e-12 47.0 0.1 8e-11 41.6 0.0 2.8 3 0 0 3 3 3 1 ICP0-binding domain of Ubiquitin-specific protease 7 USP7_C2 PF14533.1 AIO01785.1 - 1.4e-09 37.7 0.3 1.7e-06 27.6 0.0 2.4 2 0 0 2 2 2 2 Ubiquitin-specific protease C-terminal Robl_LC7 PF03259.12 AIO01786.1 - 8.1e-20 70.1 0.0 9e-20 70.0 0.0 1.0 1 0 0 1 1 1 1 Roadblock/LC7 domain Notch PF00066.12 AIO01787.1 - 0.11 12.7 0.8 0.28 11.4 0.5 1.6 1 0 0 1 1 1 0 LNR domain SpoVAB PF13782.1 AIO01788.1 - 0.11 12.4 0.3 0.15 12.0 0.2 1.2 1 0 0 1 1 1 0 Stage V sporulation protein AB Proteasom_Rpn13 PF04683.8 AIO01789.1 - 2.5e-17 62.7 0.0 3.8e-17 62.1 0.0 1.3 1 0 0 1 1 1 1 Proteasome complex subunit Rpn13 ubiquitin receptor DUF3276 PF11680.3 AIO01789.1 - 0.061 13.1 0.1 0.1 12.4 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3276) rOmpB PF12334.3 AIO01789.1 - 0.084 12.2 0.0 0.14 11.4 0.0 1.3 1 0 0 1 1 1 0 Rickettsia outer membrane protein B TMF_DNA_bd PF12329.3 AIO01790.1 - 1.1 9.0 11.3 2.2 8.1 1.5 2.2 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding DUF4140 PF13600.1 AIO01790.1 - 2.4 8.6 10.7 1.6 9.2 1.7 2.2 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) DUF972 PF06156.8 AIO01790.1 - 4.5 7.6 8.4 1.2 9.5 0.7 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF972) Atg14 PF10186.4 AIO01790.1 - 8.4 5.2 8.9 13 4.6 6.2 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DNA_pol_E_B PF04042.11 AIO01791.1 - 1.8e-19 69.8 0.0 2.7e-19 69.2 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B DTW PF03942.10 AIO01792.1 - 7e-27 93.9 0.0 1.4e-26 93.0 0.0 1.4 1 0 0 1 1 1 1 DTW domain zf-RING_3 PF14369.1 AIO01792.1 - 0.081 12.9 4.2 1.6 8.7 0.4 2.6 1 1 1 2 2 2 0 zinc-finger zf-B_box PF00643.19 AIO01792.1 - 0.24 11.3 2.2 0.4 10.6 1.5 1.3 1 0 0 1 1 1 0 B-box zinc finger GAS PF13851.1 AIO01793.1 - 6.6e-60 201.7 28.6 6.6e-60 201.7 19.8 3.1 2 1 0 2 2 2 1 Growth-arrest specific micro-tubule binding DUF948 PF06103.6 AIO01793.1 - 0.028 14.2 0.4 0.028 14.2 0.3 6.3 1 1 6 7 7 7 0 Bacterial protein of unknown function (DUF948) Filament PF00038.16 AIO01793.1 - 2.1 7.7 64.9 2.4 7.5 35.7 2.9 1 1 1 2 2 2 0 Intermediate filament protein Baculo_PEP_C PF04513.7 AIO01793.1 - 5.5 6.8 16.6 8.3 6.2 1.3 4.0 1 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Ebp2 PF05890.7 AIO01794.1 - 9.7e-57 192.3 8.9 1.6e-56 191.6 6.2 1.3 1 0 0 1 1 1 1 Eukaryotic rRNA processing protein EBP2 GvpL_GvpF PF06386.6 AIO01794.1 - 3.1 7.3 11.8 0.034 13.7 2.3 1.9 2 0 0 2 2 2 0 Gas vesicle synthesis protein GvpL/GvpF Lysine_decarbox PF03641.9 AIO01795.1 - 0.03 14.1 0.0 0.076 12.8 0.0 1.7 1 0 0 1 1 1 0 Possible lysine decarboxylase EMP24_GP25L PF01105.19 AIO01797.1 - 9.3e-41 139.5 0.3 1.3e-40 139.1 0.2 1.2 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD MogR_DNAbind PF12181.3 AIO01797.1 - 0.034 13.9 0.7 0.051 13.3 0.5 1.2 1 0 0 1 1 1 0 DNA binding domain of the motility gene repressor (MogR) Pkinase PF00069.20 AIO01798.1 - 2.6e-52 177.5 0.0 3.3e-52 177.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AIO01798.1 - 5e-19 68.3 0.0 7.9e-19 67.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Choline_kinase PF01633.15 AIO01798.1 - 0.11 12.0 0.1 0.28 10.7 0.0 1.6 2 0 0 2 2 2 0 Choline/ethanolamine kinase SH3BP5 PF05276.9 AIO01799.1 - 0.023 14.0 0.2 0.041 13.1 0.2 1.3 1 0 0 1 1 1 0 SH3 domain-binding protein 5 (SH3BP5) Ribosomal_L18p PF00861.17 AIO01800.1 - 4.9e-38 130.0 0.8 4.9e-38 130.0 0.5 1.7 2 0 0 2 2 2 1 Ribosomal L18p/L5e family Ribosomal_L18_c PF14204.1 AIO01800.1 - 3.8e-23 81.8 7.8 3.8e-23 81.8 5.4 1.7 2 0 0 2 2 2 1 Ribosomal L18 C-terminal region Phage_Integr_2 PF13009.1 AIO01800.1 - 0.11 11.4 0.4 0.16 10.8 0.3 1.2 1 0 0 1 1 1 0 Putative phage integrase Ribosomal_L15e PF00827.12 AIO01801.1 - 1.8e-88 295.0 10.8 2e-88 294.9 7.5 1.0 1 0 0 1 1 1 1 Ribosomal L15 Ribosomal_L36e PF01158.13 AIO01802.1 - 3.7e-33 113.3 2.6 4.5e-33 113.1 1.8 1.0 1 0 0 1 1 1 1 Ribosomal protein L36e EAP30 PF04157.11 AIO01805.1 - 0.047 12.8 2.4 0.08 12.0 1.6 1.3 1 0 0 1 1 1 0 EAP30/Vps36 family NYD-SP28_assoc PF14775.1 AIO01805.1 - 0.65 9.7 8.3 0.59 9.8 0.8 2.4 2 0 0 2 2 2 0 Sperm tail C-terminal domain HALZ PF02183.13 AIO01805.1 - 3.2 7.5 12.6 0.87 9.3 1.4 2.7 2 0 0 2 2 2 0 Homeobox associated leucine zipper APG6 PF04111.7 AIO01805.1 - 5.4 5.9 8.9 8 5.3 6.1 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 ATP11 PF06644.6 AIO01806.1 - 1.2e-21 77.3 0.3 1.5e-21 77.0 0.2 1.1 1 0 0 1 1 1 1 ATP11 protein UBX PF00789.15 AIO01807.1 - 3.1e-07 30.3 0.0 1.3e-06 28.3 0.0 2.0 2 0 0 2 2 2 1 UBX domain AAA_13 PF13166.1 AIO01807.1 - 0.19 10.1 4.0 0.25 9.7 2.8 1.1 1 0 0 1 1 1 0 AAA domain Asp-B-Hydro_N PF05279.6 AIO01807.1 - 1.1 9.1 16.0 1.6 8.5 11.1 1.2 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Spore_coat_CotO PF14153.1 AIO01807.1 - 1.2 8.5 10.4 1.8 7.9 6.0 2.1 2 0 0 2 2 2 0 Spore coat protein CotO Milton PF12448.3 AIO01807.1 - 2.3 8.4 9.4 0.86 9.7 4.2 1.8 1 1 1 2 2 2 0 Kinesin associated protein SAPS PF04499.10 AIO01807.1 - 3.4 6.2 6.7 4.8 5.7 4.7 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Trypsin_2 PF13365.1 AIO01808.1 - 0.0022 17.9 0.0 0.005 16.8 0.0 1.7 1 1 0 1 1 1 1 Trypsin-like peptidase domain DUF658 PF04936.7 AIO01808.1 - 0.0037 17.1 0.7 0.023 14.5 0.5 2.3 1 1 1 2 2 2 1 Protein of unknown function (DUF658) U1snRNP70_N PF12220.3 AIO01808.1 - 3.6 7.9 9.5 0.16 12.3 0.5 2.8 3 0 0 3 3 3 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal U3_assoc_6 PF08640.6 AIO01809.1 - 2.3e-18 65.7 0.9 2.2e-17 62.6 0.2 2.4 2 0 0 2 2 2 1 U3 small nucleolar RNA-associated protein 6 RmlD_sub_bind PF04321.12 AIO01811.1 - 3.1e-05 23.0 0.0 0.047 12.5 0.0 2.3 2 1 0 2 2 2 2 RmlD substrate binding domain NAD_binding_10 PF13460.1 AIO01811.1 - 0.00035 20.6 0.0 0.00061 19.8 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 AIO01811.1 - 0.0035 16.8 0.0 0.011 15.1 0.0 1.7 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family NmrA PF05368.8 AIO01811.1 - 0.041 13.1 0.0 0.064 12.4 0.0 1.2 1 0 0 1 1 1 0 NmrA-like family EF-hand_6 PF13405.1 AIO01812.1 - 2e-07 30.3 0.0 0.17 11.8 0.1 3.8 3 0 0 3 3 3 3 EF-hand domain EF-hand_7 PF13499.1 AIO01812.1 - 5.3e-07 29.6 0.0 0.77 9.9 0.0 3.5 3 0 0 3 3 3 3 EF-hand domain pair EF-hand_1 PF00036.27 AIO01812.1 - 4.8e-06 25.4 0.0 0.21 10.9 0.0 3.6 3 0 0 3 3 3 3 EF hand EF-hand_8 PF13833.1 AIO01812.1 - 0.015 14.8 0.1 45 3.7 0.0 3.6 3 0 0 3 3 3 0 EF-hand domain pair Ank_2 PF12796.2 AIO01813.1 - 1.1e-69 230.7 30.5 7.3e-11 42.2 0.1 14.8 11 5 3 15 15 15 10 Ankyrin repeats (3 copies) Ank PF00023.25 AIO01813.1 - 9.8e-42 138.7 70.7 1.7e-05 24.4 0.2 21.8 23 0 0 23 23 23 14 Ankyrin repeat Ank_5 PF13857.1 AIO01813.1 - 7.8e-38 127.6 56.3 5.7e-08 32.7 0.3 19.6 15 3 5 20 20 20 9 Ankyrin repeats (many copies) Ank_4 PF13637.1 AIO01813.1 - 6.1e-31 106.2 29.5 8.7e-05 22.9 0.0 15.5 13 5 5 18 18 18 9 Ankyrin repeats (many copies) Ank_3 PF13606.1 AIO01813.1 - 3.7e-30 100.9 44.1 0.0099 16.0 0.1 21.6 24 0 0 24 24 24 10 Ankyrin repeat Filamin PF00630.14 AIO01813.1 - 0.0002 21.8 0.0 0.00084 19.8 0.0 2.1 3 0 0 3 3 3 1 Filamin/ABP280 repeat Ribosomal_L32e PF01655.13 AIO01814.1 - 2.9e-40 136.7 0.3 3.5e-40 136.4 0.2 1.1 1 0 0 1 1 1 1 Ribosomal protein L32 SH3_9 PF14604.1 AIO01815.1 - 3.5e-34 116.1 1.0 2.2e-12 46.3 0.0 4.9 5 0 0 5 5 5 3 Variant SH3 domain SH3_1 PF00018.23 AIO01815.1 - 8.1e-28 95.5 0.5 1.7e-10 40.1 0.0 3.4 3 0 0 3 3 3 3 SH3 domain SH3_2 PF07653.12 AIO01815.1 - 2.7e-25 87.6 1.1 6.2e-12 44.8 0.1 3.7 3 0 0 3 3 3 3 Variant SH3 domain DUF4205 PF13898.1 AIO01816.1 - 1e-20 73.7 0.0 2e-20 72.8 0.0 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF4205) E1-E2_ATPase PF00122.15 AIO01817.1 - 4.2e-61 205.9 0.7 4.2e-61 205.9 0.5 1.9 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 AIO01817.1 - 3.2e-30 104.9 5.3 3.2e-30 104.9 3.7 2.4 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 AIO01817.1 - 4.4e-25 89.3 0.0 2.3e-24 86.9 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 AIO01817.1 - 4.4e-14 52.2 0.1 1.1e-13 50.9 0.0 1.7 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 AIO01817.1 - 2.8e-12 47.1 0.1 8.1e-11 42.4 0.0 2.9 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 AIO01817.1 - 2.9e-09 36.2 0.0 6e-09 35.2 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 AIO01817.1 - 1.5e-06 28.0 2.2 2.1e-05 24.2 0.2 2.4 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF4149 PF13664.1 AIO01817.1 - 6.9 6.7 15.0 6.1 6.9 2.2 4.1 3 1 0 3 3 3 0 Domain of unknown function (DUF4149) Kinesin PF00225.18 AIO01818.1 - 4.5e-72 242.5 0.1 2.3e-42 144.8 0.0 2.6 3 0 0 3 3 3 2 Kinesin motor domain Synaptobrevin PF00957.16 AIO01822.1 - 6.2e-14 51.3 0.1 9.9e-14 50.7 0.1 1.3 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.1 AIO01822.1 - 1.6e-10 40.4 0.0 2.4e-10 39.8 0.0 1.3 1 0 0 1 1 1 1 Regulated-SNARE-like domain CDC45 PF02724.9 AIO01823.1 - 0.18 9.8 13.9 0.22 9.4 9.6 1.1 1 0 0 1 1 1 0 CDC45-like protein Ycf1 PF05758.7 AIO01823.1 - 0.27 8.9 0.5 0.23 9.1 0.4 1.1 1 0 0 1 1 1 0 Ycf1 Daxx PF03344.10 AIO01823.1 - 1.5 7.2 25.7 2.1 6.7 17.8 1.2 1 0 0 1 1 1 0 Daxx Family CENP-T PF15511.1 AIO01823.1 - 7.1 5.7 21.0 15 4.6 14.5 1.5 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T DUF4303 PF14136.1 AIO01823.1 - 7.2 6.2 9.6 50 3.5 5.5 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4303) Lipase_3 PF01764.20 AIO01825.1 - 4.6e-05 23.0 0.0 0.00012 21.6 0.0 1.6 2 0 0 2 2 2 1 Lipase (class 3) PGAP1 PF07819.8 AIO01825.1 - 0.00023 20.8 0.1 0.0009 18.8 0.0 1.9 2 0 0 2 2 2 1 PGAP1-like protein Thioesterase PF00975.15 AIO01825.1 - 0.012 15.8 0.3 0.09 12.9 0.0 2.4 3 0 0 3 3 3 0 Thioesterase domain Complex1_LYR_1 PF13232.1 AIO01825.1 - 0.46 10.7 4.1 1.3 9.3 2.8 1.7 1 0 0 1 1 1 0 Complex1_LYR-like adh_short PF00106.20 AIO01826.1 - 4.7e-10 39.6 1.0 1.9e-09 37.6 0.1 2.3 2 1 0 2 2 2 1 short chain dehydrogenase A_deaminase PF00962.17 AIO01827.1 - 2.5e-57 194.3 0.0 2.9e-57 194.0 0.0 1.1 1 0 0 1 1 1 1 Adenosine/AMP deaminase adh_short PF00106.20 AIO01828.1 - 3.5e-12 46.5 1.6 4.6e-11 42.9 1.1 2.3 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 AIO01828.1 - 0.00093 18.9 1.2 0.0028 17.3 0.6 1.9 2 0 0 2 2 2 1 KR domain 3HCDH_N PF02737.13 AIO01828.1 - 0.062 12.9 0.1 0.11 12.1 0.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain adh_short_C2 PF13561.1 AIO01828.1 - 0.081 12.6 0.0 0.12 12.1 0.0 1.3 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase NmrA PF05368.8 AIO01828.1 - 0.17 11.1 0.4 0.49 9.6 0.1 1.8 2 0 0 2 2 2 0 NmrA-like family Ribosomal_L11_N PF03946.9 AIO01830.1 - 7e-15 54.2 0.2 1.3e-14 53.4 0.1 1.5 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.14 AIO01830.1 - 1e-10 41.5 0.6 2e-10 40.6 0.4 1.5 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain RRM_1 PF00076.17 AIO01831.1 - 7.1e-36 121.6 0.0 4.6e-17 61.4 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 AIO01831.1 - 2.6e-29 101.0 0.1 4.3e-14 52.2 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 AIO01831.1 - 2.2e-10 40.2 0.0 3.7e-05 23.4 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 AIO01831.1 - 0.00034 20.3 0.2 2.7 7.8 0.0 3.6 3 1 0 3 3 3 2 Limkain b1 KMP11 PF03037.11 AIO01832.1 - 3.3e-56 187.8 18.2 3.6e-56 187.7 12.6 1.0 1 0 0 1 1 1 1 Kinetoplastid membrane protein 11 Apolipoprotein PF01442.13 AIO01832.1 - 0.0084 15.6 4.7 0.013 15.0 3.2 1.3 1 1 0 1 1 1 1 Apolipoprotein A1/A4/E domain Lyase_8_N PF08124.6 AIO01832.1 - 0.018 13.9 2.5 0.019 13.8 1.7 1.1 1 0 0 1 1 1 0 Polysaccharide lyase family 8, N terminal alpha-helical domain Herpes_BLRF2 PF05812.7 AIO01832.1 - 0.021 14.6 2.6 0.026 14.3 1.8 1.2 1 0 0 1 1 1 0 Herpesvirus BLRF2 protein AAA_32 PF13654.1 AIO01832.1 - 0.023 13.3 4.3 0.026 13.2 3.0 1.0 1 0 0 1 1 1 0 AAA domain DUF3584 PF12128.3 AIO01832.1 - 0.032 11.5 5.0 0.041 11.2 3.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) FCH PF00611.18 AIO01832.1 - 0.041 14.0 1.0 0.041 14.0 0.7 1.8 1 1 1 2 2 2 0 Fes/CIP4, and EFC/F-BAR homology domain Psb28 PF03912.9 AIO01832.1 - 0.066 13.1 1.1 0.086 12.8 0.7 1.3 1 1 0 1 1 1 0 Psb28 protein FdsD PF11390.3 AIO01832.1 - 0.093 12.8 1.7 0.22 11.6 1.2 1.8 1 1 0 1 1 1 0 NADH-dependant formate dehydrogenase delta subunit FdsD Brr6_like_C_C PF10104.4 AIO01832.1 - 0.096 12.2 0.7 0.1 12.0 0.5 1.1 1 0 0 1 1 1 0 Di-sulfide bridge nucleocytoplasmic transport domain Metal_resist PF13801.1 AIO01832.1 - 0.15 12.0 2.1 0.34 10.9 0.2 1.9 1 1 1 2 2 2 0 Heavy-metal resistance NYD-SP28 PF14772.1 AIO01832.1 - 0.21 11.7 8.1 1.9 8.6 0.3 2.5 2 1 1 3 3 3 0 Sperm tail HrcA PF01628.16 AIO01832.1 - 0.22 11.0 1.3 0.26 10.8 0.9 1.0 1 0 0 1 1 1 0 HrcA protein C terminal domain T5orf172 PF10544.4 AIO01832.1 - 0.22 11.9 2.8 0.26 11.6 1.9 1.2 1 0 0 1 1 1 0 T5orf172 domain MRP-S27 PF10037.4 AIO01832.1 - 0.36 9.7 5.4 0.38 9.6 3.8 1.0 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S27 DUF4404 PF14357.1 AIO01832.1 - 0.37 11.2 4.3 2.4 8.6 0.4 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4404) ARL2_Bind_BART PF11527.3 AIO01832.1 - 0.4 10.4 9.5 0.63 9.8 6.6 1.4 1 1 0 1 1 1 0 The ARF-like 2 binding protein BART Exonuc_VII_L PF02601.10 AIO01832.1 - 0.55 9.3 3.2 0.59 9.2 2.2 1.0 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF3994 PF13159.1 AIO01832.1 - 0.57 10.4 3.6 0.57 10.4 0.4 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3994) Phage_GPO PF05929.6 AIO01832.1 - 0.72 9.0 4.0 0.87 8.7 2.7 1.0 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase TroA PF01297.12 AIO01832.1 - 0.88 8.7 3.4 4.8 6.3 0.1 2.0 1 1 1 2 2 2 0 Periplasmic solute binding protein family TipAS PF07739.8 AIO01832.1 - 0.96 9.7 10.0 0.62 10.3 1.4 2.0 2 0 0 2 2 2 0 TipAS antibiotic-recognition domain DUF3417 PF11897.3 AIO01832.1 - 1 9.3 4.9 6.5 6.7 0.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3417) DUF778 PF05608.7 AIO01832.1 - 1 9.2 3.9 1.4 8.8 2.5 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF778) DUF922 PF06037.6 AIO01832.1 - 1.4 8.2 6.2 1.8 7.9 3.9 1.5 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF922) DUF148 PF02520.12 AIO01832.1 - 1.5 8.6 8.0 9.3 6.0 2.2 2.2 1 1 1 2 2 2 0 Domain of unknown function DUF148 DUF2884 PF11101.3 AIO01832.1 - 1.6 8.0 8.2 4.6 6.5 0.3 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF2884) Rho_Binding PF08912.6 AIO01832.1 - 1.7 9.0 11.0 0.26 11.5 2.0 2.2 1 1 1 2 2 2 0 Rho Binding YtxH PF12732.2 AIO01832.1 - 2.5 8.5 4.7 15 6.0 3.3 1.9 1 1 0 1 1 1 0 YtxH-like protein CCDC-167 PF15188.1 AIO01832.1 - 3.5 7.6 5.8 11 6.0 4.0 1.7 1 1 1 2 2 2 0 Coiled-coil domain-containing protein 167 Vps54 PF07928.7 AIO01832.1 - 3.9 7.6 5.1 4.2 7.5 1.6 1.9 2 0 0 2 2 2 0 Vps54-like protein NYN_YacP PF05991.6 AIO01832.1 - 4.3 7.0 5.9 0.77 9.4 0.5 1.8 1 1 1 2 2 2 0 YacP-like NYN domain PWWP PF00855.12 AIO01832.1 - 6.3 7.0 7.3 11 6.3 5.1 1.4 1 1 0 1 1 1 0 PWWP domain Vma12 PF11712.3 AIO01832.1 - 8.3 6.1 9.1 96 2.6 6.3 2.2 1 1 0 1 1 1 0 Endoplasmic reticulum-based factor for assembly of V-ATPase KMP11 PF03037.11 AIO01833.1 - 9.2e-56 186.4 17.9 1e-55 186.2 12.4 1.0 1 0 0 1 1 1 1 Kinetoplastid membrane protein 11 Apolipoprotein PF01442.13 AIO01833.1 - 0.0096 15.4 4.0 0.015 14.8 2.8 1.3 1 1 0 1 1 1 1 Apolipoprotein A1/A4/E domain Herpes_BLRF2 PF05812.7 AIO01833.1 - 0.017 14.8 2.1 0.022 14.5 1.5 1.2 1 0 0 1 1 1 0 Herpesvirus BLRF2 protein Lyase_8_N PF08124.6 AIO01833.1 - 0.019 13.8 2.4 0.02 13.7 1.7 1.1 1 0 0 1 1 1 0 Polysaccharide lyase family 8, N terminal alpha-helical domain GrpE PF01025.14 AIO01833.1 - 0.03 13.8 4.8 0.033 13.7 3.3 1.1 1 0 0 1 1 1 0 GrpE AAA_32 PF13654.1 AIO01833.1 - 0.031 12.9 4.0 0.034 12.8 2.8 1.0 1 0 0 1 1 1 0 AAA domain DUF3584 PF12128.3 AIO01833.1 - 0.035 11.4 4.4 0.044 11.1 3.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) FCH PF00611.18 AIO01833.1 - 0.05 13.7 3.2 0.061 13.5 1.1 1.8 1 1 1 2 2 2 0 Fes/CIP4, and EFC/F-BAR homology domain Psb28 PF03912.9 AIO01833.1 - 0.069 13.1 1.3 0.084 12.8 0.9 1.3 1 0 0 1 1 1 0 Psb28 protein Brr6_like_C_C PF10104.4 AIO01833.1 - 0.12 11.8 0.6 0.13 11.7 0.4 1.1 1 0 0 1 1 1 0 Di-sulfide bridge nucleocytoplasmic transport domain FdsD PF11390.3 AIO01833.1 - 0.12 12.4 1.5 0.31 11.1 1.1 1.8 1 1 0 1 1 1 0 NADH-dependant formate dehydrogenase delta subunit FdsD NYD-SP28 PF14772.1 AIO01833.1 - 0.18 11.9 7.5 1.9 8.6 0.3 2.5 2 1 0 2 2 2 0 Sperm tail Metal_resist PF13801.1 AIO01833.1 - 0.19 11.7 2.1 0.43 10.5 0.2 1.9 1 1 1 2 2 2 0 Heavy-metal resistance HrcA PF01628.16 AIO01833.1 - 0.22 11.0 1.1 0.26 10.8 0.7 1.0 1 0 0 1 1 1 0 HrcA protein C terminal domain T5orf172 PF10544.4 AIO01833.1 - 0.24 11.8 2.4 0.28 11.5 1.6 1.2 1 0 0 1 1 1 0 T5orf172 domain ARL2_Bind_BART PF11527.3 AIO01833.1 - 0.25 11.1 9.0 0.39 10.5 6.3 1.4 1 1 0 1 1 1 0 The ARF-like 2 binding protein BART MRP-S27 PF10037.4 AIO01833.1 - 0.35 9.7 5.0 0.37 9.6 3.5 1.0 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S27 DUF4404 PF14357.1 AIO01833.1 - 0.5 10.8 3.6 4.7 7.7 0.3 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4404) DUF3994 PF13159.1 AIO01833.1 - 0.54 10.5 3.6 0.57 10.4 0.4 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3994) DUF922 PF06037.6 AIO01833.1 - 0.64 9.3 5.7 0.8 9.0 3.6 1.5 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF922) TipAS PF07739.8 AIO01833.1 - 0.88 9.9 9.5 0.64 10.3 1.2 2.0 2 0 0 2 2 2 0 TipAS antibiotic-recognition domain DUF2884 PF11101.3 AIO01833.1 - 1.1 8.5 8.1 4.6 6.5 0.3 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2884) DUF778 PF05608.7 AIO01833.1 - 1.2 9.0 3.5 1.7 8.6 2.2 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF778) YtxH PF12732.2 AIO01833.1 - 1.2 9.5 4.5 7.7 6.9 3.1 1.9 1 1 0 1 1 1 0 YtxH-like protein DUF3417 PF11897.3 AIO01833.1 - 1.3 9.0 4.8 6.8 6.6 0.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3417) Rho_Binding PF08912.6 AIO01833.1 - 1.6 9.1 10.2 0.9 9.8 2.9 2.2 1 1 1 2 2 2 0 Rho Binding DUF148 PF02520.12 AIO01833.1 - 2.7 7.7 7.9 14 5.5 0.6 2.2 1 1 1 2 2 2 0 Domain of unknown function DUF148 Pox_polyA_pol_N PF12630.2 AIO01833.1 - 5 7.2 5.6 9.8 6.3 3.8 1.6 1 1 0 1 1 1 0 Poxvirus poly(A) polymerase N-terminal domain PWWP PF00855.12 AIO01833.1 - 5.3 7.3 7.1 9.1 6.5 4.9 1.4 1 1 0 1 1 1 0 PWWP domain Vma12 PF11712.3 AIO01833.1 - 6.5 6.4 8.8 1.5 8.5 1.4 2.2 1 1 1 2 2 2 0 Endoplasmic reticulum-based factor for assembly of V-ATPase KMP11 PF03037.11 AIO01834.1 - 9.2e-56 186.4 17.9 1e-55 186.2 12.4 1.0 1 0 0 1 1 1 1 Kinetoplastid membrane protein 11 Apolipoprotein PF01442.13 AIO01834.1 - 0.0096 15.4 4.0 0.015 14.8 2.8 1.3 1 1 0 1 1 1 1 Apolipoprotein A1/A4/E domain Herpes_BLRF2 PF05812.7 AIO01834.1 - 0.017 14.8 2.1 0.022 14.5 1.5 1.2 1 0 0 1 1 1 0 Herpesvirus BLRF2 protein Lyase_8_N PF08124.6 AIO01834.1 - 0.019 13.8 2.4 0.02 13.7 1.7 1.1 1 0 0 1 1 1 0 Polysaccharide lyase family 8, N terminal alpha-helical domain GrpE PF01025.14 AIO01834.1 - 0.03 13.8 4.8 0.033 13.7 3.3 1.1 1 0 0 1 1 1 0 GrpE AAA_32 PF13654.1 AIO01834.1 - 0.031 12.9 4.0 0.034 12.8 2.8 1.0 1 0 0 1 1 1 0 AAA domain DUF3584 PF12128.3 AIO01834.1 - 0.035 11.4 4.4 0.044 11.1 3.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) FCH PF00611.18 AIO01834.1 - 0.05 13.7 3.2 0.061 13.5 1.1 1.8 1 1 1 2 2 2 0 Fes/CIP4, and EFC/F-BAR homology domain Psb28 PF03912.9 AIO01834.1 - 0.069 13.1 1.3 0.084 12.8 0.9 1.3 1 0 0 1 1 1 0 Psb28 protein Brr6_like_C_C PF10104.4 AIO01834.1 - 0.12 11.8 0.6 0.13 11.7 0.4 1.1 1 0 0 1 1 1 0 Di-sulfide bridge nucleocytoplasmic transport domain FdsD PF11390.3 AIO01834.1 - 0.12 12.4 1.5 0.31 11.1 1.1 1.8 1 1 0 1 1 1 0 NADH-dependant formate dehydrogenase delta subunit FdsD NYD-SP28 PF14772.1 AIO01834.1 - 0.18 11.9 7.5 1.9 8.6 0.3 2.5 2 1 0 2 2 2 0 Sperm tail Metal_resist PF13801.1 AIO01834.1 - 0.19 11.7 2.1 0.43 10.5 0.2 1.9 1 1 1 2 2 2 0 Heavy-metal resistance HrcA PF01628.16 AIO01834.1 - 0.22 11.0 1.1 0.26 10.8 0.7 1.0 1 0 0 1 1 1 0 HrcA protein C terminal domain T5orf172 PF10544.4 AIO01834.1 - 0.24 11.8 2.4 0.28 11.5 1.6 1.2 1 0 0 1 1 1 0 T5orf172 domain ARL2_Bind_BART PF11527.3 AIO01834.1 - 0.25 11.1 9.0 0.39 10.5 6.3 1.4 1 1 0 1 1 1 0 The ARF-like 2 binding protein BART MRP-S27 PF10037.4 AIO01834.1 - 0.35 9.7 5.0 0.37 9.6 3.5 1.0 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S27 DUF4404 PF14357.1 AIO01834.1 - 0.5 10.8 3.6 4.7 7.7 0.3 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4404) DUF3994 PF13159.1 AIO01834.1 - 0.54 10.5 3.6 0.57 10.4 0.4 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3994) DUF922 PF06037.6 AIO01834.1 - 0.64 9.3 5.7 0.8 9.0 3.6 1.5 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF922) TipAS PF07739.8 AIO01834.1 - 0.88 9.9 9.5 0.64 10.3 1.2 2.0 2 0 0 2 2 2 0 TipAS antibiotic-recognition domain DUF2884 PF11101.3 AIO01834.1 - 1.1 8.5 8.1 4.6 6.5 0.3 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2884) DUF778 PF05608.7 AIO01834.1 - 1.2 9.0 3.5 1.7 8.6 2.2 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF778) YtxH PF12732.2 AIO01834.1 - 1.2 9.5 4.5 7.7 6.9 3.1 1.9 1 1 0 1 1 1 0 YtxH-like protein DUF3417 PF11897.3 AIO01834.1 - 1.3 9.0 4.8 6.8 6.6 0.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3417) Rho_Binding PF08912.6 AIO01834.1 - 1.6 9.1 10.2 0.9 9.8 2.9 2.2 1 1 1 2 2 2 0 Rho Binding DUF148 PF02520.12 AIO01834.1 - 2.7 7.7 7.9 14 5.5 0.6 2.2 1 1 1 2 2 2 0 Domain of unknown function DUF148 Pox_polyA_pol_N PF12630.2 AIO01834.1 - 5 7.2 5.6 9.8 6.3 3.8 1.6 1 1 0 1 1 1 0 Poxvirus poly(A) polymerase N-terminal domain PWWP PF00855.12 AIO01834.1 - 5.3 7.3 7.1 9.1 6.5 4.9 1.4 1 1 0 1 1 1 0 PWWP domain Vma12 PF11712.3 AIO01834.1 - 6.5 6.4 8.8 1.5 8.5 1.4 2.2 1 1 1 2 2 2 0 Endoplasmic reticulum-based factor for assembly of V-ATPase Med7 PF05983.6 AIO01837.1 - 1.6 8.4 0.0 3.6 7.3 0.0 1.5 1 0 0 1 1 1 0 MED7 protein ATP-grasp_4 PF13535.1 AIO01838.1 - 2.2e-22 79.7 0.0 5.3e-22 78.4 0.0 1.7 1 1 0 1 1 1 1 ATP-grasp domain ATPgrasp_Ter PF15632.1 AIO01838.1 - 1.1e-08 34.2 0.0 0.0019 17.0 0.0 2.1 2 0 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp_3 PF02655.9 AIO01838.1 - 0.00077 19.3 0.0 0.0035 17.2 0.0 2.0 1 1 0 1 1 1 1 ATP-grasp domain CPSase_L_D2 PF02786.12 AIO01838.1 - 0.063 12.5 0.0 7.8 5.7 0.0 2.3 2 0 0 2 2 2 0 Carbamoyl-phosphate synthase L chain, ATP binding domain Dala_Dala_lig_C PF07478.8 AIO01838.1 - 0.067 12.5 0.0 31 3.8 0.0 3.0 3 0 0 3 3 3 0 D-ala D-ala ligase C-terminus Helicase_C PF00271.26 AIO01839.1 - 1.1e-07 31.5 0.0 2.6e-07 30.3 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 AIO01839.1 - 2.1e-06 27.3 0.0 5.5e-06 25.9 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase COX16 PF14138.1 AIO01843.1 - 0.12 12.5 0.0 0.24 11.6 0.0 1.6 1 0 0 1 1 1 0 Cytochrome c oxidase assembly protein COX16 Pkinase PF00069.20 AIO01844.1 - 1.2e-43 149.2 0.1 1.9e-25 89.5 0.0 3.3 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 AIO01844.1 - 2.9e-25 88.8 0.0 2.7e-22 79.0 0.1 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 AIO01844.1 - 3.4e-06 26.2 0.0 0.00089 18.2 0.0 2.2 2 0 0 2 2 2 2 Kinase-like Exostosin PF03016.10 AIO01844.1 - 0.052 12.5 0.2 0.13 11.2 0.0 1.7 2 0 0 2 2 2 0 Exostosin family Pox_ser-thr_kin PF05445.6 AIO01844.1 - 0.15 10.8 0.0 0.22 10.2 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase APH PF01636.18 AIO01844.1 - 0.18 11.4 0.8 1 9.0 0.1 2.4 3 0 0 3 3 3 0 Phosphotransferase enzyme family HEAT PF02985.17 AIO01845.1 - 2e-06 27.3 4.9 8.7 6.7 0.0 7.3 6 0 0 6 6 6 2 HEAT repeat HEAT_EZ PF13513.1 AIO01845.1 - 8.3e-06 26.1 9.0 0.024 15.1 0.0 6.4 6 1 1 7 7 7 2 HEAT-like repeat DUF1546 PF07571.8 AIO01845.1 - 0.0066 16.5 0.0 3.5 7.7 0.0 4.0 4 0 0 4 4 4 1 Protein of unknown function (DUF1546) IBN_N PF03810.14 AIO01845.1 - 0.012 15.4 2.2 0.079 12.8 0.7 2.7 2 0 0 2 2 2 0 Importin-beta N-terminal domain 2Fe-2S_thioredx PF01257.14 AIO01845.1 - 0.053 13.1 0.1 0.11 12.0 0.0 1.5 1 0 0 1 1 1 0 Thioredoxin-like [2Fe-2S] ferredoxin CAF1 PF04857.15 AIO01846.1 - 6.2e-25 88.0 0.0 6.5e-17 61.7 0.0 2.3 2 0 0 2 2 2 2 CAF1 family ribonuclease Peptidase_M24 PF00557.19 AIO01847.1 - 1.4e-49 168.5 1.2 2e-49 168.0 0.8 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.11 AIO01847.1 - 4.8e-32 110.1 0.0 8.9e-32 109.2 0.0 1.5 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain DUF1764 PF08576.5 AIO01848.1 - 9.8e-16 58.3 1.4 1.6e-15 57.6 0.1 1.9 2 1 0 2 2 2 1 Eukaryotic protein of unknown function (DUF1764) SET PF00856.23 AIO01849.1 - 1.6e-07 31.8 0.0 3.2e-05 24.3 0.0 3.3 3 1 0 3 3 3 1 SET domain Spt4 PF06093.8 AIO01851.1 - 3.6e-10 39.5 0.0 4.5e-10 39.2 0.0 1.2 1 0 0 1 1 1 1 Spt4/RpoE2 zinc finger WD40 PF00400.27 AIO01852.1 - 7.7e-09 35.1 3.0 0.0009 19.0 0.0 5.5 5 0 0 5 5 5 2 WD domain, G-beta repeat PQQ_2 PF13360.1 AIO01852.1 - 2.9e-05 23.6 0.3 2.9e-05 23.6 0.2 2.9 4 0 0 4 4 4 1 PQQ-like domain LRR_6 PF13516.1 AIO01852.1 - 0.19 11.9 0.0 12 6.3 0.0 3.1 3 0 0 3 3 3 0 Leucine Rich repeat UCH PF00443.24 AIO01853.1 - 9e-42 143.0 0.0 6.2e-41 140.2 0.0 2.1 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 AIO01853.1 - 9.5e-13 48.2 0.1 2.7e-11 43.4 0.0 2.8 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Vps5 PF09325.5 AIO01854.1 - 1.5e-18 66.9 4.6 2e-18 66.5 3.2 1.1 1 0 0 1 1 1 1 Vps5 C terminal like PX PF00787.19 AIO01854.1 - 2.1e-15 56.5 0.0 5.1e-15 55.2 0.0 1.6 1 0 0 1 1 1 1 PX domain FTCD_C PF04961.7 AIO01854.1 - 0.015 14.7 0.3 0.032 13.6 0.2 1.5 1 0 0 1 1 1 0 Formiminotransferase-cyclodeaminase KapB PF08810.5 AIO01854.1 - 0.062 13.3 0.6 0.24 11.4 0.2 2.2 3 1 0 3 3 3 0 Kinase associated protein B FAA_hydrolase PF01557.13 AIO01856.1 - 8.6e-41 139.7 0.0 6e-40 137.0 0.0 1.9 1 1 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family DUF3490 PF11995.3 AIO01856.1 - 0.019 14.5 0.0 0.03 13.8 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3490) HECT PF00632.20 AIO01857.1 - 3.4e-79 266.2 0.0 6.1e-79 265.4 0.0 1.4 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Nop53 PF07767.6 AIO01859.1 - 3.8e-12 45.9 18.6 1.8e-09 37.0 12.9 3.0 1 1 0 1 1 1 1 Nop53 (60S ribosomal biogenesis) DUF1053 PF06327.9 AIO01859.1 - 0.22 11.8 4.8 2.3 8.6 0.0 2.5 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1053) Lge1 PF11488.3 AIO01859.1 - 1.8 8.8 5.9 15 5.8 0.1 2.6 2 1 0 2 2 2 0 Transcriptional regulatory protein LGE1 DUF2346 PF09803.4 AIO01859.1 - 5.4 6.9 7.4 0.72 9.7 0.1 2.8 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2346) GAS PF13851.1 AIO01860.1 - 4.1 6.5 20.3 0.9 8.7 6.6 2.4 1 1 0 2 2 2 0 Growth-arrest specific micro-tubule binding AAA_13 PF13166.1 AIO01860.1 - 4.4 5.6 8.7 6.4 5.0 6.0 1.1 1 0 0 1 1 1 0 AAA domain APG6 PF04111.7 AIO01860.1 - 7.1 5.5 27.4 4.3 6.2 9.4 2.2 1 1 1 2 2 2 0 Autophagy protein Apg6 Propep_M14 PF02244.11 AIO01861.1 - 0.11 12.1 0.1 0.48 10.1 0.0 2.0 2 0 0 2 2 2 0 Carboxypeptidase activation peptide Yos1 PF08571.5 AIO01862.1 - 2.2e-29 101.3 1.8 3.2e-29 100.8 1.3 1.2 1 1 0 1 1 1 1 Yos1-like zf-RING_2 PF13639.1 AIO01863.1 - 4.7e-15 55.1 11.9 6.3e-07 29.1 0.4 3.4 3 0 0 3 3 3 2 Ring finger domain zf-RING_5 PF14634.1 AIO01863.1 - 8.3e-09 35.0 14.0 7.3e-05 22.4 0.4 4.1 3 1 0 3 3 3 2 zinc-RING finger domain zf-C3HC4_3 PF13920.1 AIO01863.1 - 2.4e-06 27.0 11.8 0.0017 18.0 0.3 3.7 3 0 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 AIO01863.1 - 7.1e-06 25.9 14.7 0.0028 17.6 0.7 4.0 3 1 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 AIO01863.1 - 4.2e-05 23.5 11.0 0.019 15.0 0.2 4.0 3 1 1 4 4 4 2 RING-H2 zinc finger IQ PF00612.22 AIO01863.1 - 0.00018 20.8 3.5 0.00031 20.1 1.2 2.5 2 0 0 2 2 2 1 IQ calmodulin-binding motif zf-C3HC4 PF00097.20 AIO01863.1 - 0.019 14.6 16.0 0.45 10.2 0.1 4.6 4 1 0 4 4 4 0 Zinc finger, C3HC4 type (RING finger) LIM PF00412.17 AIO01863.1 - 0.5 10.4 4.5 2.9 8.0 0.1 3.2 3 0 0 3 3 3 0 LIM domain Prok-RING_4 PF14447.1 AIO01863.1 - 1.5 8.4 16.0 7.7 6.1 0.1 5.0 5 0 0 5 5 5 0 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.1 AIO01863.1 - 2 8.1 16.1 6.7 6.5 0.1 5.1 5 0 0 5 5 5 0 RING-type zinc-finger zf-Apc11 PF12861.2 AIO01863.1 - 2.6 7.9 14.2 2.1 8.2 0.8 4.1 3 2 0 3 3 3 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-MIZ PF02891.15 AIO01863.1 - 3.5 7.2 8.6 5.3 6.6 0.2 3.7 3 0 0 3 3 3 0 MIZ/SP-RING zinc finger Claudin_3 PF06653.6 AIO01865.1 - 0.23 11.2 9.3 0.1 12.3 3.6 2.0 2 0 0 2 2 2 0 Tight junction protein, Claudin-like TMEM173 PF15009.1 AIO01865.1 - 0.37 9.5 1.7 0.51 9.0 1.2 1.2 1 0 0 1 1 1 0 Transmembrane protein 173 RRM_1 PF00076.17 AIO01866.1 - 1.4e-26 91.9 0.1 3e-14 52.3 0.0 3.5 2 1 1 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 AIO01866.1 - 8.4e-26 89.7 0.2 3.6e-11 42.8 0.0 3.3 2 1 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 AIO01866.1 - 0.0011 18.7 0.0 1.3 8.9 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FAD_binding_1 PF00667.15 AIO01867.1 - 4.1e-32 111.3 0.0 7e-32 110.6 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.20 AIO01867.1 - 7e-16 58.5 0.0 1.8e-11 44.2 0.0 2.5 2 0 0 2 2 2 2 Flavodoxin FAD_binding_6 PF00970.19 AIO01867.1 - 8.7e-05 22.5 0.0 0.00023 21.2 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.16 AIO01867.1 - 0.00033 21.1 0.1 0.0067 16.9 0.0 2.5 1 1 1 2 2 2 1 Oxidoreductase NAD-binding domain Cortex-I_coil PF09304.5 AIO01868.1 - 0.1 12.6 1.2 0.16 12.0 0.9 1.2 1 0 0 1 1 1 0 Cortexillin I, coiled coil CcoS PF03597.10 AIO01869.1 - 0.12 11.8 0.2 0.21 11.0 0.2 1.3 1 0 0 1 1 1 0 Cytochrome oxidase maturation protein cbb3-type Sigma70_r1_2 PF00140.15 AIO01869.1 - 9.7 5.9 7.1 8.7 6.1 0.0 2.7 3 0 0 3 3 3 0 Sigma-70 factor, region 1.2 zf-DHHC PF01529.15 AIO01870.1 - 1.8e-28 99.1 6.1 1.8e-28 99.1 4.2 1.5 1 1 0 1 1 1 1 DHHC palmitoyltransferase NIF PF03031.13 AIO01872.1 - 7.1e-27 94.0 0.2 1.2e-26 93.3 0.1 1.3 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase HAD_2 PF13419.1 AIO01872.1 - 0.0084 16.3 0.4 0.013 15.7 0.3 1.3 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase zf-HC5HC2H PF13771.1 AIO01873.1 - 1.1e-06 28.6 6.0 1.1e-06 28.6 4.2 2.3 2 1 0 2 2 2 1 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.1 AIO01873.1 - 0.00075 19.4 9.3 0.00075 19.4 6.4 2.4 2 1 0 2 2 2 1 PHD-zinc-finger like domain TruD PF01142.13 AIO01874.1 - 1.3e-05 24.0 0.0 0.054 12.1 0.0 2.7 2 1 0 2 2 2 2 tRNA pseudouridine synthase D (TruD) Ank PF00023.25 AIO01877.1 - 1.7e-27 93.7 4.2 5.3e-12 44.9 0.0 4.3 5 0 0 5 5 5 3 Ankyrin repeat Ank_4 PF13637.1 AIO01877.1 - 3.4e-25 87.9 2.0 8.5e-11 42.0 0.1 3.2 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_2 PF12796.2 AIO01877.1 - 2e-24 85.7 1.8 2e-14 53.6 0.0 2.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.1 AIO01877.1 - 7.7e-24 83.1 4.7 8.5e-12 44.9 0.1 3.6 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 AIO01877.1 - 1.3e-21 74.4 0.1 6.6e-07 28.9 0.0 4.2 5 0 0 5 5 5 3 Ankyrin repeat GATase_7 PF13537.1 AIO01877.1 - 0.12 12.0 0.1 0.81 9.4 0.0 2.1 1 1 2 3 3 3 0 Glutamine amidotransferase domain BTB_2 PF02214.17 AIO01878.1 - 3.1e-12 46.5 0.0 1.5e-11 44.3 0.0 2.0 2 0 0 2 2 2 1 BTB/POZ domain TRAPPC9-Trs120 PF08626.6 AIO01879.1 - 9.3e-09 33.2 0.0 1.2e-05 22.9 0.0 3.3 2 1 0 2 2 2 2 Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit SNARE PF05739.14 AIO01881.1 - 7.4e-20 70.3 0.6 7.4e-20 70.3 0.4 2.6 3 0 0 3 3 3 1 SNARE domain Syntaxin PF00804.20 AIO01881.1 - 0.00043 20.4 12.6 0.00092 19.3 2.0 2.6 1 1 2 3 3 3 2 Syntaxin Lipoprotein_6 PF01441.14 AIO01881.1 - 0.016 15.0 1.4 0.056 13.2 0.3 2.1 2 0 0 2 2 2 0 Lipoprotein MutS_III PF05192.13 AIO01881.1 - 0.12 12.1 3.7 0.099 12.4 0.2 2.1 2 1 0 2 2 2 0 MutS domain III Acyl-CoA_dh_1 PF00441.19 AIO01883.1 - 1.7e-41 141.7 3.4 2.5e-41 141.2 2.3 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 AIO01883.1 - 1.1e-23 84.0 0.0 2.9e-23 82.6 0.0 1.8 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.6 AIO01883.1 - 1.8e-21 76.7 0.1 3.1e-21 76.0 0.1 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 AIO01883.1 - 1.6e-19 69.0 0.8 5e-19 67.5 0.3 2.0 3 0 0 3 3 3 1 Acyl-CoA dehydrogenase, middle domain HpaB_N PF11794.3 AIO01883.1 - 0.043 13.2 0.3 0.52 9.6 0.2 2.6 1 1 1 2 2 2 0 4-hydroxyphenylacetate 3-hydroxylase N terminal GalKase_gal_bdg PF10509.4 AIO01884.1 - 6.6e-18 63.7 0.0 1.9e-17 62.2 0.0 1.8 1 0 0 1 1 1 1 Galactokinase galactose-binding signature GHMP_kinases_C PF08544.8 AIO01884.1 - 2e-07 31.1 0.0 6.1e-07 29.5 0.0 1.8 1 0 0 1 1 1 1 GHMP kinases C terminal GHMP_kinases_N PF00288.21 AIO01884.1 - 8.1e-07 29.0 0.1 2.1e-06 27.6 0.0 1.8 1 0 0 1 1 1 1 GHMP kinases N terminal domain Muted PF14942.1 AIO01885.1 - 0.0091 15.8 8.3 0.0091 15.8 5.8 3.1 4 0 0 4 4 4 1 Organelle biogenesis, Muted-like protein Pox_P35 PF03213.9 AIO01885.1 - 0.34 9.8 0.8 1.1 8.2 0.0 1.9 2 0 0 2 2 2 0 Poxvirus P35 protein Speriolin_N PF15058.1 AIO01885.1 - 2.6 7.9 9.8 0.25 11.2 1.6 2.8 3 0 0 3 3 3 0 Speriolin N terminus DUF342 PF03961.8 AIO01885.1 - 8.7 4.6 10.4 8.2 4.7 6.3 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF342) MMR_HSR1 PF01926.18 AIO01886.1 - 9.9e-05 22.2 0.0 0.00022 21.1 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 AIO01886.1 - 0.0021 17.3 0.0 0.024 13.9 0.0 2.4 3 0 0 3 3 3 1 Ferrous iron transport protein B Arch_ATPase PF01637.13 AIO01886.1 - 0.074 12.7 0.1 0.21 11.2 0.0 1.7 2 0 0 2 2 2 0 Archaeal ATPase AAA_22 PF13401.1 AIO01886.1 - 0.13 12.3 0.0 8.6 6.5 0.0 2.6 1 1 1 2 2 2 0 AAA domain GTP_EFTU PF00009.22 AIO01886.1 - 0.15 11.5 0.0 0.49 9.8 0.0 1.8 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain Miro PF08477.8 AIO01886.1 - 0.18 12.3 0.0 0.65 10.4 0.0 1.9 2 0 0 2 2 2 0 Miro-like protein IQ PF00612.22 AIO01887.1 - 1.2e-05 24.4 1.7 4.8e-05 22.6 1.2 2.1 1 0 0 1 1 1 1 IQ calmodulin-binding motif Dpy-30 PF05186.8 AIO01887.1 - 0.015 14.7 0.1 0.033 13.6 0.0 1.6 1 0 0 1 1 1 0 Dpy-30 motif MFS_1 PF07690.11 AIO01888.1 - 4.9e-23 81.4 43.2 2e-17 62.9 14.9 2.3 1 1 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 AIO01888.1 - 1.2e-06 27.4 13.2 1.2e-06 27.4 9.2 2.4 2 1 0 2 2 2 1 Sugar (and other) transporter FAM163 PF15069.1 AIO01889.1 - 0.016 15.7 0.1 0.034 14.7 0.0 1.5 1 0 0 1 1 1 0 FAM163 family DUF4492 PF14899.1 AIO01889.1 - 0.061 12.8 0.2 0.12 11.9 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4492) UPF0370 PF13980.1 AIO01889.1 - 0.31 10.8 5.4 0.62 9.9 3.8 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0370) TMEM52 PF14979.1 AIO01889.1 - 0.33 10.8 4.0 0.55 10.1 2.1 1.8 2 0 0 2 2 2 0 Transmembrane 52 DUF3753 PF12575.3 AIO01889.1 - 0.38 10.5 1.8 1 9.2 1.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3753) Abhydrolase_1 PF00561.15 AIO01890.1 - 6.2e-07 29.1 0.1 8.6e-07 28.7 0.1 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 AIO01890.1 - 1.7e-06 28.0 0.1 3e-06 27.2 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 AIO01890.1 - 6.3e-06 26.0 0.0 1.3e-05 25.0 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF818 PF05677.7 AIO01890.1 - 1.2e-05 24.1 0.0 1.6e-05 23.8 0.0 1.2 1 0 0 1 1 1 1 Chlamydia CHLPS protein (DUF818) Peptidase_S9 PF00326.16 AIO01890.1 - 0.0017 17.6 0.0 0.0023 17.1 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family DUF2305 PF10230.4 AIO01890.1 - 0.0022 17.4 0.1 0.021 14.2 0.0 2.1 2 0 0 2 2 2 1 Uncharacterised conserved protein (DUF2305) Abhydrolase_3 PF07859.8 AIO01890.1 - 0.03 13.8 0.0 0.051 13.1 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold DUF676 PF05057.9 AIO01890.1 - 0.055 12.7 0.0 0.19 10.9 0.0 1.8 2 0 0 2 2 2 0 Putative serine esterase (DUF676) Esterase_phd PF10503.4 AIO01890.1 - 0.13 11.5 0.1 0.21 10.8 0.1 1.2 1 0 0 1 1 1 0 Esterase PHB depolymerase MFS_1 PF07690.11 AIO01891.1 - 5.7e-20 71.3 42.4 3.8e-18 65.3 12.7 2.6 2 2 1 3 3 3 3 Major Facilitator Superfamily Sugar_tr PF00083.19 AIO01891.1 - 7.5e-05 21.4 10.4 7.5e-05 21.4 7.2 3.3 3 1 0 3 3 3 1 Sugar (and other) transporter MFS_1_like PF12832.2 AIO01891.1 - 0.0011 18.6 0.0 0.005 16.5 0.0 2.1 1 0 0 1 1 1 1 MFS_1 like family MFS_1 PF07690.11 AIO01892.1 - 3.5e-21 75.3 10.7 3.7e-21 75.2 7.4 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 AIO01892.1 - 2.1e-05 23.2 10.3 2.9e-05 22.8 7.1 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_2 PF13347.1 AIO01892.1 - 6e-05 21.6 6.1 6e-05 21.6 4.3 1.4 2 0 0 2 2 2 1 MFS/sugar transport protein MFS_1_like PF12832.2 AIO01892.1 - 0.00033 20.3 0.0 0.0012 18.5 0.0 1.9 1 0 0 1 1 1 1 MFS_1 like family MFS_1 PF07690.11 AIO01893.1 - 5.4e-25 87.8 33.5 3e-20 72.2 5.3 2.3 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 AIO01893.1 - 1e-06 27.6 4.0 1e-06 27.6 2.8 2.2 2 0 0 2 2 2 1 Sugar (and other) transporter Aminotran_5 PF00266.14 AIO01895.1 - 1.2e-49 169.0 0.4 1.4e-33 116.1 0.1 2.1 2 0 0 2 2 2 2 Aminotransferase class-V Beta_elim_lyase PF01212.16 AIO01895.1 - 0.002 17.3 0.0 0.0044 16.2 0.0 1.5 1 0 0 1 1 1 1 Beta-eliminating lyase MRF_C1 PF13887.1 AIO01895.1 - 0.075 12.0 0.2 0.4 9.7 0.2 2.1 2 0 0 2 2 2 0 Myelin gene regulatory factor -C-terminal domain 1 Leo1 PF04004.8 AIO01896.1 - 2.4e-18 66.4 0.0 5.5e-18 65.2 0.0 1.7 1 0 0 1 1 1 1 Leo1-like protein Alb1 PF09135.6 AIO01897.1 - 0.003 18.1 7.7 0.003 18.1 5.3 2.3 1 1 1 2 2 2 1 Alb1 PLC-beta_C PF08703.5 AIO01897.1 - 0.031 13.9 16.6 0.12 12.0 6.2 2.1 2 0 0 2 2 2 0 PLC-beta C terminal DIT1_PvcA PF05141.7 AIO01897.1 - 0.33 10.2 7.9 0.42 9.8 5.5 1.2 1 0 0 1 1 1 0 Pyoverdine/dityrosine biosynthesis protein PLRV_ORF5 PF01690.12 AIO01897.1 - 8.8 5.3 8.4 9.8 5.1 5.8 1.1 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein Pkinase PF00069.20 AIO01898.1 - 6.3e-09 35.3 0.0 1e-05 24.8 0.0 2.8 3 0 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.12 AIO01898.1 - 8.2e-06 25.0 0.0 4.4e-05 22.6 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase Tmpp129 PF10272.4 AIO01898.1 - 0.037 12.7 0.0 0.061 12.0 0.0 1.2 1 0 0 1 1 1 0 Putative transmembrane protein precursor Sybindin PF04099.7 AIO01899.1 - 2.8e-17 62.7 0.1 3.2e-17 62.5 0.1 1.0 1 0 0 1 1 1 1 Sybindin-like family Tmpp129 PF10272.4 AIO01899.1 - 0.018 13.7 0.0 0.018 13.7 0.0 1.1 1 0 0 1 1 1 0 Putative transmembrane protein precursor CHU_C PF13585.1 AIO01899.1 - 0.057 13.3 0.1 0.092 12.6 0.1 1.4 1 0 0 1 1 1 0 C-terminal domain of CHU protein family SpoU_methylase PF00588.14 AIO01900.1 - 5.5e-08 32.7 0.0 1.7e-07 31.2 0.0 1.8 1 0 0 1 1 1 1 SpoU rRNA Methylase family Tctex-1 PF03645.8 AIO01902.1 - 5.6e-29 99.9 0.1 6.5e-29 99.7 0.0 1.0 1 0 0 1 1 1 1 Tctex-1 family DSPc PF00782.15 AIO01902.1 - 0.006 16.1 0.0 0.008 15.7 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Pox_VLTF3 PF04947.9 AIO01902.1 - 0.09 12.2 0.4 0.13 11.7 0.2 1.2 1 0 0 1 1 1 0 Poxvirus Late Transcription Factor VLTF3 like DUF4200 PF13863.1 AIO01903.1 - 0.011 15.6 7.3 0.028 14.3 5.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) TMF_DNA_bd PF12329.3 AIO01903.1 - 0.012 15.3 1.0 0.028 14.2 0.7 1.6 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding Kinetocho_Slk19 PF12709.2 AIO01903.1 - 0.076 13.0 3.2 0.14 12.2 0.5 2.4 1 1 1 2 2 2 0 Central kinetochore-associated DUF2968 PF11180.3 AIO01903.1 - 6 6.2 15.8 0.42 9.9 6.7 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2968) Cupin_8 PF13621.1 AIO01905.1 - 1.4e-44 152.5 0.0 2.6e-44 151.6 0.0 1.4 1 0 0 1 1 1 1 Cupin-like domain LCM PF04072.9 AIO01905.1 - 1.2e-16 60.7 0.0 1.2e-08 34.7 0.0 2.6 2 1 0 2 2 2 2 Leucine carboxyl methyltransferase Kelch_5 PF13854.1 AIO01905.1 - 7.9e-10 38.4 0.7 0.34 10.8 0.0 5.7 5 0 0 5 5 5 4 Kelch motif Cupin_4 PF08007.7 AIO01905.1 - 0.00024 20.4 0.0 0.0007 18.9 0.0 1.5 1 1 0 1 1 1 1 Cupin superfamily protein Kelch_3 PF13415.1 AIO01905.1 - 0.002 18.2 7.3 3.5 7.9 0.0 5.0 4 1 0 4 4 4 2 Galactose oxidase, central domain Kelch_4 PF13418.1 AIO01905.1 - 0.047 13.4 8.9 0.27 11.0 0.0 4.9 6 0 0 6 6 6 0 Galactose oxidase, central domain PPR PF01535.15 AIO01906.1 - 3.7e-22 76.6 29.4 0.011 15.6 0.0 12.2 14 0 0 14 14 14 6 PPR repeat PPR_2 PF13041.1 AIO01906.1 - 3.4e-21 74.9 14.5 6.9e-07 29.1 0.0 9.6 6 3 5 11 11 11 7 PPR repeat family PPR_3 PF13812.1 AIO01906.1 - 2.6e-18 64.7 24.8 0.0017 18.4 0.1 13.6 15 0 0 15 15 15 6 Pentatricopeptide repeat domain PPR_1 PF12854.2 AIO01906.1 - 2.3e-11 42.9 0.0 0.13 11.8 0.0 6.4 5 0 0 5 5 5 3 PPR repeat TPR_19 PF14559.1 AIO01906.1 - 0.003 17.8 1.5 4.1 7.8 0.0 5.3 6 1 1 7 7 7 1 Tetratricopeptide repeat RNA_pol_Rpb4 PF03874.11 AIO01906.1 - 0.025 14.5 0.6 30 4.6 0.0 4.6 4 2 1 5 5 5 0 RNA polymerase Rpb4 DENN PF02141.16 AIO01907.1 - 2.1e-23 82.9 0.4 4.2e-23 82.0 0.3 1.4 1 0 0 1 1 1 1 DENN (AEX-3) domain SPA PF08616.5 AIO01907.1 - 0.0015 18.2 0.3 0.0036 16.9 0.2 1.6 1 0 0 1 1 1 1 Stabilization of polarity axis uDENN PF03456.13 AIO01907.1 - 0.05 13.5 0.0 0.12 12.3 0.0 1.7 1 0 0 1 1 1 0 uDENN domain YceG PF02618.11 AIO01908.1 - 0.02 13.9 0.1 0.9 8.5 0.0 2.1 2 0 0 2 2 2 0 YceG-like family TPR_11 PF13414.1 AIO01908.1 - 0.023 14.3 0.7 0.83 9.3 0.1 2.4 1 1 1 2 2 2 0 TPR repeat TPR_14 PF13428.1 AIO01908.1 - 0.098 13.3 1.2 4.1 8.3 0.1 3.4 2 1 2 4 4 4 0 Tetratricopeptide repeat TPR_2 PF07719.12 AIO01908.1 - 0.5 10.4 2.3 36 4.6 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat DnaJ PF00226.26 AIO01909.1 - 1.9e-22 78.7 0.8 3.7e-22 77.8 0.6 1.5 1 0 0 1 1 1 1 DnaJ domain CTDII PF01556.13 AIO01909.1 - 6e-20 70.9 0.9 4.6e-17 61.6 0.3 2.4 2 0 0 2 2 2 2 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.14 AIO01909.1 - 2.5e-15 56.2 19.0 4.9e-15 55.3 13.1 1.5 1 0 0 1 1 1 1 DnaJ central domain HypA PF01155.14 AIO01909.1 - 0.037 13.7 7.7 0.053 13.2 0.6 2.3 2 0 0 2 2 2 0 Hydrogenase expression/synthesis hypA family Cytochrom_c3_2 PF14537.1 AIO01909.1 - 0.29 11.5 8.5 0.58 10.5 5.9 1.5 1 0 0 1 1 1 0 Cytochrome c3 DNA_pol_A_exo1 PF01612.15 AIO01910.1 - 5.5e-15 55.2 0.0 8.3e-15 54.7 0.0 1.2 1 0 0 1 1 1 1 3'-5' exonuclease zf-CCHC PF00098.18 AIO01910.1 - 0.0023 17.7 1.8 0.0023 17.7 1.2 4.9 5 0 0 5 5 5 3 Zinc knuckle DUF2063 PF09836.4 AIO01910.1 - 0.14 12.1 0.0 0.38 10.7 0.0 1.6 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2063) zf-C4_ClpX PF06689.8 AIO01910.1 - 4.5 6.8 11.1 8.6 5.9 0.3 3.0 2 1 0 2 2 2 0 ClpX C4-type zinc finger CAF-1_p60_C PF15512.1 AIO01911.1 - 0.24 11.8 1.7 0.42 11.0 1.2 1.4 1 0 0 1 1 1 0 Chromatin assembly factor complex 1 subunit p60, C-terminal Glyoxalase PF00903.20 AIO01912.1 - 9.4e-16 57.9 0.2 1.2e-15 57.6 0.1 1.1 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.2 AIO01912.1 - 1e-14 55.0 0.1 1.2e-14 54.7 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase_4 PF13669.1 AIO01912.1 - 8.4e-11 41.8 0.0 1.4e-10 41.1 0.0 1.4 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily CppA_N PF14506.1 AIO01912.1 - 0.019 14.6 0.0 0.028 14.0 0.0 1.3 1 1 0 1 1 1 0 CppA N-terminal Oxidored_q1_N PF00662.15 AIO01912.1 - 0.029 13.9 0.1 0.15 11.6 0.1 1.9 1 1 1 2 2 2 0 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus Glyoxalase_3 PF13468.1 AIO01912.1 - 0.081 12.8 0.0 12 5.7 0.0 2.5 2 1 0 2 2 2 0 Glyoxalase-like domain PAF-AH_p_II PF03403.8 AIO01913.1 - 7e-27 93.6 0.0 4.5e-26 91.0 0.0 1.9 1 1 0 1 1 1 1 Platelet-activating factor acetylhydrolase, isoform II Abhydrolase_5 PF12695.2 AIO01913.1 - 3.5e-10 39.8 0.0 5.1e-10 39.2 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 AIO01913.1 - 3.2e-08 33.7 0.3 7.4e-08 32.5 0.2 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Chlorophyllase2 PF12740.2 AIO01913.1 - 0.0021 16.9 0.1 0.0098 14.8 0.0 1.9 1 1 0 1 1 1 1 Chlorophyllase enzyme Abhydrolase_1 PF00561.15 AIO01913.1 - 0.023 14.2 0.0 0.032 13.7 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold Lipase_3 PF01764.20 AIO01913.1 - 0.06 12.9 0.0 0.19 11.3 0.0 1.8 2 0 0 2 2 2 0 Lipase (class 3) Chorion_S16 PF05836.7 AIO01913.1 - 0.094 12.6 0.0 0.2 11.5 0.0 1.5 1 0 0 1 1 1 0 Chorion protein S16 PGAP1 PF07819.8 AIO01913.1 - 0.13 11.8 0.0 0.23 11.0 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein Ser_hydrolase PF06821.8 AIO01913.1 - 0.15 11.6 0.1 0.84 9.2 0.0 2.1 2 1 1 3 3 3 0 Serine hydrolase ICMT PF04140.9 AIO01914.1 - 4.6e-20 71.6 1.3 4.6e-20 71.6 0.9 2.0 2 1 0 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.8 AIO01914.1 - 6.1e-09 35.9 1.7 6.1e-09 35.9 1.2 2.9 3 2 2 5 5 5 1 Phospholipid methyltransferase DUF1295 PF06966.7 AIO01914.1 - 0.0011 18.3 2.1 0.0011 18.3 1.5 1.9 2 1 1 3 3 3 1 Protein of unknown function (DUF1295) RseC_MucC PF04246.7 AIO01914.1 - 0.0063 16.0 1.8 0.035 13.6 0.2 2.2 2 0 0 2 2 2 1 Positive regulator of sigma(E), RseC/MucC DUF2721 PF11026.3 AIO01914.1 - 0.021 14.4 2.5 0.08 12.5 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2721) HXXEE PF13787.1 AIO01914.1 - 0.028 14.7 0.4 0.028 14.7 0.2 2.4 3 0 0 3 3 3 0 Protein of unknown function with HXXEE motif Flavi_M PF01004.14 AIO01914.1 - 0.11 11.9 1.0 0.37 10.2 0.7 1.9 1 0 0 1 1 1 0 Flavivirus envelope glycoprotein M CopD PF05425.8 AIO01914.1 - 3.2 8.0 10.1 4.7 7.4 0.1 3.5 3 1 1 4 4 4 0 Copper resistance protein D NDUFA12 PF05071.11 AIO01915.1 - 0.00012 22.4 0.3 0.00012 22.4 0.2 1.8 2 0 0 2 2 2 1 NADH ubiquinone oxidoreductase subunit NDUFA12 zf-RING_UBOX PF13445.1 AIO01916.1 - 5e-05 22.9 0.6 0.00012 21.7 0.4 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-CCHC_2 PF13696.1 AIO01916.1 - 7.2e-05 22.1 4.7 7.2e-05 22.1 3.3 2.5 2 0 0 2 2 2 1 Zinc knuckle zf-RING_4 PF14570.1 AIO01916.1 - 0.00025 20.5 3.2 0.00025 20.5 2.2 1.8 2 0 0 2 2 2 1 RING/Ubox like zinc-binding domain zf-RING_5 PF14634.1 AIO01916.1 - 0.0012 18.4 4.5 0.0012 18.4 3.1 2.4 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 AIO01916.1 - 0.0019 18.2 1.6 0.0019 18.2 1.1 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 AIO01916.1 - 0.0027 17.3 3.5 0.0027 17.3 2.5 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 AIO01916.1 - 0.0046 16.7 4.0 0.013 15.3 2.8 1.7 1 0 0 1 1 1 1 Ring finger domain Trypan_PARP PF05887.6 AIO01916.1 - 0.036 13.8 0.5 0.074 12.8 0.3 1.4 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) zf-C3HC4 PF00097.20 AIO01916.1 - 0.065 12.9 3.9 0.18 11.5 2.7 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Rtf2 PF04641.7 AIO01916.1 - 0.11 11.7 0.2 0.16 11.1 0.2 1.2 1 0 0 1 1 1 0 Rtf2 RING-finger FYVE PF01363.16 AIO01916.1 - 0.48 10.3 6.0 0.16 11.8 1.4 2.1 2 0 0 2 2 2 0 FYVE zinc finger Prok-RING_4 PF14447.1 AIO01916.1 - 0.95 9.0 7.0 0.22 11.0 1.8 2.1 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 DUF4428 PF14471.1 AIO01916.1 - 1.1 9.1 5.0 31 4.4 0.2 3.3 2 1 0 2 2 2 0 Domain of unknown function (DUF4428) zf-CCHC PF00098.18 AIO01916.1 - 1.7 8.7 10.7 0.085 12.8 3.1 2.2 2 0 0 2 2 1 0 Zinc knuckle TF_Zn_Ribbon PF08271.7 AIO01916.1 - 4.9 6.5 8.0 2.2 7.6 1.6 2.7 2 1 0 2 2 2 0 TFIIB zinc-binding ThiF PF00899.16 AIO01917.1 - 3.5e-47 159.6 0.2 1.2e-33 115.7 0.1 2.4 2 0 0 2 2 2 2 ThiF family UBACT PF02134.16 AIO01917.1 - 4.6e-28 96.5 2.2 1.7e-26 91.6 0.0 3.0 3 0 0 3 3 3 1 Repeat in ubiquitin-activating (UBA) protein UBA_e1_thiolCys PF10585.4 AIO01917.1 - 1.4e-16 59.6 0.0 2.7e-16 58.6 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-activating enzyme active site 3HCDH_N PF02737.13 AIO01917.1 - 0.042 13.5 0.1 0.12 11.9 0.0 1.8 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Rhamno_transf PF11316.3 AIO01917.1 - 0.11 11.6 0.2 0.21 10.7 0.1 1.4 1 0 0 1 1 1 0 Putative rhamnosyl transferase CrtC PF07143.6 AIO01918.1 - 8.3e-07 28.6 0.9 2.5e-06 27.0 0.1 2.2 2 1 0 2 2 2 1 Hydroxyneurosporene synthase (CrtC) Peptidase_C74 PF12387.3 AIO01918.1 - 0.0036 16.5 0.3 0.039 13.0 0.1 2.3 2 0 0 2 2 2 1 Pestivirus NS2 peptidase FGGY_N PF00370.16 AIO01919.1 - 8.7e-68 228.2 0.0 1.2e-67 227.8 0.0 1.2 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain FGGY_C PF02782.11 AIO01919.1 - 6e-59 198.9 0.8 1.1e-58 198.1 0.5 1.4 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain BcrAD_BadFG PF01869.15 AIO01919.1 - 0.085 12.1 0.0 6.9 5.8 0.0 2.6 2 1 0 2 2 2 0 BadF/BadG/BcrA/BcrD ATPase family DnaJ PF00226.26 AIO01920.1 - 7.1e-11 41.6 0.0 1.7e-10 40.4 0.0 1.6 1 0 0 1 1 1 1 DnaJ domain DEAD PF00270.24 AIO01921.1 - 4.3e-39 133.7 0.0 5.2e-37 126.9 0.0 2.1 2 0 0 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.26 AIO01921.1 - 1.5e-26 92.0 0.2 3.4e-26 90.8 0.1 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Helicase_C_2 PF13307.1 AIO01921.1 - 0.0055 16.6 0.0 0.01 15.7 0.0 1.4 1 0 0 1 1 1 1 Helicase C-terminal domain ResIII PF04851.10 AIO01921.1 - 0.042 13.6 0.0 0.32 10.7 0.0 2.2 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit DUF1253 PF06862.7 AIO01921.1 - 0.14 10.5 0.1 2.9 6.1 0.0 2.4 2 1 1 3 3 3 0 Protein of unknown function (DUF1253) Dynein_light PF01221.13 AIO01924.1 - 1.8e-12 47.0 0.1 2.9e-12 46.3 0.1 1.3 1 0 0 1 1 1 1 Dynein light chain type 1 Ground-like PF04155.13 AIO01924.1 - 7.9e-05 22.8 0.0 0.00017 21.8 0.0 1.6 1 1 0 1 1 1 1 Ground-like domain IPK PF03770.11 AIO01925.1 - 7.1e-23 81.2 0.0 1e-21 77.5 0.0 2.2 1 1 0 1 1 1 1 Inositol polyphosphate kinase Flavokinase PF01687.12 AIO01927.1 - 2.4e-28 98.5 0.0 2.8e-28 98.3 0.0 1.1 1 0 0 1 1 1 1 Riboflavin kinase Pkinase PF00069.20 AIO01928.1 - 2.2e-38 131.9 0.0 3.8e-38 131.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AIO01928.1 - 1.6e-15 56.8 0.0 4.8e-14 52.0 0.0 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 AIO01928.1 - 0.00016 21.4 0.0 0.00016 21.4 0.0 2.5 2 1 0 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.17 AIO01928.1 - 0.0022 17.3 0.0 0.0042 16.4 0.0 1.4 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.9 AIO01928.1 - 0.025 13.6 0.0 0.052 12.6 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 AIO01928.1 - 0.49 9.6 0.0 0.88 8.8 0.0 1.3 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL His_Phos_1 PF00300.17 AIO01930.1 - 2.2e-09 37.5 0.0 5.2e-08 33.1 0.0 2.2 2 0 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) DUF3040 PF11239.3 AIO01930.1 - 0.14 12.2 0.6 0.55 10.3 0.4 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3040) DUF4389 PF14333.1 AIO01930.1 - 8.4 6.1 9.1 0.35 10.6 0.4 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4389) RRM_1 PF00076.17 AIO01931.1 - 2e-06 27.3 0.0 4.3e-06 26.2 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 AIO01931.1 - 7.4e-05 22.6 0.0 0.00018 21.4 0.0 1.7 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 AIO01931.1 - 0.00019 21.1 0.0 0.00034 20.3 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) EF-hand_7 PF13499.1 AIO01932.1 - 1e-09 38.3 0.3 1.7e-08 34.4 0.2 2.5 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.27 AIO01932.1 - 0.0024 17.0 4.3 0.043 13.1 0.1 3.3 3 0 0 3 3 3 1 EF hand EF-hand_6 PF13405.1 AIO01932.1 - 0.0039 16.9 0.7 0.079 12.8 0.0 3.0 3 0 0 3 3 3 1 EF-hand domain EF-hand_8 PF13833.1 AIO01932.1 - 0.0086 15.6 2.0 2.2 7.9 0.1 2.8 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.1 AIO01932.1 - 0.042 13.2 0.9 0.12 11.7 0.0 2.2 2 0 0 2 2 2 0 EF hand dCMP_cyt_deam_1 PF00383.17 AIO01933.1 - 1.1 8.9 4.5 3.5 7.3 0.1 2.2 2 0 0 2 2 2 0 Cytidine and deoxycytidylate deaminase zinc-binding region Phage_fiber_2 PF03406.8 AIO01933.1 - 5.9 6.5 10.3 19 4.9 3.0 2.6 2 0 0 2 2 2 0 Phage tail fibre repeat Cys_Met_Meta_PP PF01053.15 AIO01934.1 - 2e-127 424.7 0.1 2.2e-127 424.5 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.12 AIO01934.1 - 9.4e-10 38.0 1.4 2.4e-09 36.7 0.1 1.9 1 1 1 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.14 AIO01934.1 - 0.0002 20.2 0.1 0.00042 19.1 0.0 1.6 1 1 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.16 AIO01934.1 - 0.00037 19.7 0.5 0.001 18.2 0.4 1.6 1 1 0 1 1 1 1 Beta-eliminating lyase AAA PF00004.24 AIO01936.1 - 2e-15 57.1 0.0 3.8e-15 56.2 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.10 AIO01936.1 - 2.2e-12 46.4 0.0 9e-10 37.8 0.0 2.1 1 1 1 2 2 2 2 Rad17 cell cycle checkpoint protein DNA_pol3_delta2 PF13177.1 AIO01936.1 - 3.5e-12 46.2 0.0 2e-11 43.8 0.0 2.0 1 1 0 1 1 1 1 DNA polymerase III, delta subunit Rep_fac_C PF08542.6 AIO01936.1 - 6.8e-09 35.5 0.0 4.5e-08 32.9 0.0 2.3 3 0 0 3 3 2 1 Replication factor C C-terminal domain AAA_22 PF13401.1 AIO01936.1 - 3.8e-07 30.3 0.1 3e-06 27.4 0.1 2.4 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 AIO01936.1 - 6.3e-07 29.0 0.0 1.6e-06 27.7 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain AAA_30 PF13604.1 AIO01936.1 - 7.1e-07 29.0 0.0 1.9e-06 27.6 0.0 1.6 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 AIO01936.1 - 7.9e-07 29.2 0.1 5.5e-05 23.2 0.0 2.4 1 1 0 2 2 2 1 AAA ATPase domain AAA_14 PF13173.1 AIO01936.1 - 3e-06 27.1 0.0 6e-06 26.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 AIO01936.1 - 7.5e-06 25.6 0.2 0.0021 17.6 0.0 2.8 2 1 1 3 3 3 1 AAA domain Mg_chelatase PF01078.16 AIO01936.1 - 9e-06 24.9 0.0 1.5e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 AIO01936.1 - 2e-05 24.3 0.0 5.8e-05 22.8 0.0 1.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_23 PF13476.1 AIO01936.1 - 0.00027 21.3 0.0 0.00037 20.8 0.0 1.2 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.7 AIO01936.1 - 0.00029 19.9 0.0 0.00055 19.0 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_29 PF13555.1 AIO01936.1 - 0.00051 19.5 0.0 0.0012 18.3 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain NB-ARC PF00931.17 AIO01936.1 - 0.0014 17.5 0.0 0.33 9.7 0.0 2.2 2 0 0 2 2 2 1 NB-ARC domain Arch_ATPase PF01637.13 AIO01936.1 - 0.0014 18.3 0.0 0.0025 17.5 0.0 1.4 1 0 0 1 1 1 1 Archaeal ATPase AAA_33 PF13671.1 AIO01936.1 - 0.0016 18.3 0.1 0.0054 16.6 0.0 2.0 2 1 0 2 2 2 1 AAA domain AAA_3 PF07726.6 AIO01936.1 - 0.0023 17.5 0.0 0.019 14.5 0.0 2.3 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) DUF2075 PF09848.4 AIO01936.1 - 0.0032 16.4 0.0 0.0048 15.9 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_10 PF12846.2 AIO01936.1 - 0.0037 16.7 0.0 0.74 9.1 0.0 2.2 1 1 1 2 2 2 1 AAA-like domain DUF815 PF05673.8 AIO01936.1 - 0.0049 15.8 0.0 0.008 15.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) Sigma54_activ_2 PF14532.1 AIO01936.1 - 0.0069 16.4 0.0 0.25 11.3 0.0 2.3 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_24 PF13479.1 AIO01936.1 - 0.0089 15.6 0.3 0.019 14.5 0.2 1.4 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 AIO01936.1 - 0.0096 16.7 0.0 0.028 15.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.12 AIO01936.1 - 0.012 15.0 0.0 0.44 9.9 0.0 2.3 2 0 0 2 2 2 0 IstB-like ATP binding protein DEAD PF00270.24 AIO01936.1 - 0.017 14.6 0.3 0.22 11.0 0.0 2.1 1 1 0 2 2 2 0 DEAD/DEAH box helicase Sigma54_activat PF00158.21 AIO01936.1 - 0.023 14.1 0.0 0.12 11.8 0.0 2.0 1 1 0 1 1 1 0 Sigma-54 interaction domain DSBA PF01323.15 AIO01936.1 - 0.042 13.4 0.1 0.097 12.2 0.0 1.6 2 0 0 2 2 1 0 DSBA-like thioredoxin domain AAA_25 PF13481.1 AIO01936.1 - 0.048 13.0 0.0 0.13 11.6 0.0 1.7 2 0 0 2 2 2 0 AAA domain ArgK PF03308.11 AIO01936.1 - 0.051 12.3 0.1 0.25 10.1 0.1 1.9 1 1 0 1 1 1 0 ArgK protein FtsK_SpoIIIE PF01580.13 AIO01936.1 - 0.073 12.5 0.0 0.16 11.4 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family ABC_tran PF00005.22 AIO01936.1 - 0.076 13.3 0.0 0.15 12.3 0.0 1.6 1 1 0 1 1 1 0 ABC transporter T2SE PF00437.15 AIO01936.1 - 0.1 11.4 0.0 0.19 10.5 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein SNF2_N PF00176.18 AIO01936.1 - 0.11 11.2 0.0 0.42 9.3 0.0 1.9 2 0 0 2 2 2 0 SNF2 family N-terminal domain AAA_28 PF13521.1 AIO01936.1 - 0.11 12.4 0.0 0.22 11.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain ResIII PF04851.10 AIO01936.1 - 0.14 11.9 0.0 0.84 9.4 0.0 1.9 1 1 1 2 2 2 0 Type III restriction enzyme, res subunit AAA_18 PF13238.1 AIO01936.1 - 0.14 12.4 0.0 0.3 11.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain Pex19 PF04614.7 AIO01937.1 - 1.1e-14 54.6 25.9 2.6e-14 53.4 0.1 3.2 2 1 1 3 3 3 2 Pex19 protein family Amidase PF01425.16 AIO01937.1 - 0.0066 15.3 0.1 0.011 14.6 0.0 1.3 1 1 0 1 1 1 1 Amidase PPR_2 PF13041.1 AIO01937.1 - 0.066 13.2 0.1 0.27 11.2 0.1 2.1 1 0 0 1 1 1 0 PPR repeat family DSX_dimer PF08828.5 AIO01937.1 - 0.31 10.5 2.5 2.2 7.8 0.0 3.1 3 0 0 3 3 3 0 Doublesex dimerisation domain MIP-T3 PF10243.4 AIO01938.1 - 1.3 7.4 19.5 1.6 7.1 13.5 1.0 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Macoilin PF09726.4 AIO01938.1 - 4.4 5.4 17.4 5.4 5.1 12.1 1.0 1 0 0 1 1 1 0 Transmembrane protein Peptidase_S64 PF08192.6 AIO01938.1 - 6.4 4.9 12.6 7.9 4.6 8.7 1.0 1 0 0 1 1 1 0 Peptidase family S64 Ribosomal_L31e PF01198.14 AIO01939.1 - 4.9e-28 96.6 0.5 1.1e-27 95.4 0.3 1.6 1 0 0 1 1 1 1 Ribosomal protein L31e WD40 PF00400.27 AIO01940.1 - 6.1e-06 25.9 14.1 0.0031 17.3 0.3 5.7 6 1 0 6 6 6 3 WD domain, G-beta repeat LRR_4 PF12799.2 AIO01941.1 - 2.6e-12 46.0 5.2 4.9e-07 29.2 0.4 2.9 2 1 1 3 3 3 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 AIO01941.1 - 8.2e-07 28.6 4.4 0.00033 20.3 0.2 2.2 1 1 0 2 2 2 2 Leucine rich repeat LRR_9 PF14580.1 AIO01941.1 - 1.5e-06 27.9 0.4 3.1e-05 23.5 0.0 1.9 1 1 1 2 2 2 1 Leucine-rich repeat LRR_6 PF13516.1 AIO01941.1 - 4.9e-06 26.0 5.2 0.054 13.5 0.1 4.3 2 1 2 4 4 4 2 Leucine Rich repeat LRR_1 PF00560.28 AIO01941.1 - 4.6e-05 22.8 5.0 0.19 11.8 0.0 4.0 4 0 0 4 4 4 2 Leucine Rich Repeat LRR_7 PF13504.1 AIO01941.1 - 0.11 12.8 3.8 10 6.8 0.0 3.9 3 1 0 3 3 3 0 Leucine rich repeat TRAPP PF04051.11 AIO01942.1 - 5.8e-27 94.0 0.0 6.8e-27 93.8 0.0 1.0 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component Mito_carr PF00153.22 AIO01943.1 - 7.7e-53 176.1 0.1 7.5e-20 70.4 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein 6PGD PF00393.14 AIO01944.1 - 2e-88 296.3 0.0 3.4e-88 295.6 0.0 1.3 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.10 AIO01944.1 - 1.3e-46 158.4 0.1 3.1e-46 157.1 0.0 1.6 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase Shikimate_DH PF01488.15 AIO01944.1 - 0.0002 21.4 0.1 0.00095 19.2 0.0 2.1 1 1 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase 3HCDH_N PF02737.13 AIO01944.1 - 0.00033 20.3 0.0 0.00056 19.6 0.0 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_Gly3P_dh_N PF01210.18 AIO01944.1 - 0.0057 16.3 0.0 0.012 15.3 0.0 1.6 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus 2-Hacid_dh_C PF02826.14 AIO01944.1 - 0.006 15.7 0.1 0.011 14.8 0.0 1.5 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain F420_oxidored PF03807.12 AIO01944.1 - 0.013 15.8 0.1 0.027 14.8 0.0 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent RuvA_C PF07499.8 AIO01944.1 - 0.022 14.8 0.0 0.048 13.8 0.0 1.5 1 0 0 1 1 1 0 RuvA, C-terminal domain Pyr_redox_2 PF07992.9 AIO01944.1 - 0.058 13.2 0.0 0.1 12.4 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 AIO01944.1 - 0.079 11.8 0.0 0.17 10.7 0.0 1.5 1 0 0 1 1 1 0 FAD dependent oxidoreductase Git3 PF11710.3 AIO01944.1 - 0.092 12.2 0.0 0.21 11.1 0.0 1.4 1 1 0 1 1 1 0 G protein-coupled glucose receptor regulating Gpa2 TP_methylase PF00590.15 AIO01945.1 - 3e-22 79.3 3.1 5.3e-22 78.5 0.1 2.6 3 1 0 3 3 3 1 Tetrapyrrole (Corrin/Porphyrin) Methylases DUF2428 PF10350.4 AIO01946.1 - 8.6e-55 185.5 0.1 2.7e-54 183.8 0.1 2.0 1 0 0 1 1 1 1 Putative death-receptor fusion protein (DUF2428) HEAT PF02985.17 AIO01946.1 - 0.001 18.9 10.7 3.3 8.0 0.2 6.5 6 0 0 6 6 6 2 HEAT repeat DUF2865 PF11064.3 AIO01946.1 - 0.0016 18.3 0.0 0.0073 16.1 0.0 2.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2865) HA2 PF04408.18 AIO01947.1 - 0.032 14.2 0.0 0.078 12.9 0.0 1.6 1 0 0 1 1 1 0 Helicase associated domain (HA2) PARP_regulatory PF01358.13 AIO01948.1 - 2.3e-17 62.5 0.0 1.7e-09 36.7 0.0 2.5 2 1 0 2 2 2 2 Poly A polymerase regulatory subunit CDC50 PF03381.10 AIO01950.1 - 2.8e-87 292.4 0.0 4.9e-87 291.6 0.0 1.3 1 1 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family DUF3185 PF11381.3 AIO01950.1 - 0.027 14.2 0.5 0.049 13.4 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3185) TOH_N PF12549.3 AIO01952.1 - 0.0044 16.5 0.4 0.02 14.4 0.3 2.1 1 0 0 1 1 1 1 Tyrosine hydroxylase N terminal Rep_fac-A_3 PF08661.6 AIO01954.1 - 3.6e-08 33.2 0.0 7.8e-08 32.2 0.0 1.5 1 1 0 1 1 1 1 Replication factor A protein 3 BHD_3 PF10405.4 AIO01955.1 - 1.3e-21 76.0 0.0 3.8e-21 74.5 0.0 1.8 2 0 0 2 2 2 1 Rad4 beta-hairpin domain 3 Rad4 PF03835.10 AIO01955.1 - 1.6e-19 69.7 0.2 4e-19 68.4 0.1 1.7 1 0 0 1 1 1 1 Rad4 transglutaminase-like domain BHD_1 PF10403.4 AIO01955.1 - 7e-11 41.4 0.0 1.5e-10 40.4 0.0 1.6 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 1 BHD_2 PF10404.4 AIO01955.1 - 6.1e-07 29.6 0.0 2e-06 28.0 0.0 2.0 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 2 Ribosomal_L21p PF00829.16 AIO01955.1 - 0.38 10.9 1.6 0.56 10.3 0.4 1.8 2 0 0 2 2 2 0 Ribosomal prokaryotic L21 protein peroxidase PF00141.18 AIO01956.1 - 8.2e-09 35.2 0.0 1e-08 34.9 0.0 1.3 1 0 0 1 1 1 1 Peroxidase Acyl_transf_1 PF00698.16 AIO01957.1 - 3.6e-21 75.8 0.0 8.2e-20 71.3 0.0 2.6 3 0 0 3 3 3 1 Acyl transferase domain MFS_1_like PF12832.2 AIO01958.1 - 0.007 16.1 0.1 0.022 14.5 0.1 1.9 1 0 0 1 1 1 1 MFS_1 like family Peptidase_U4 PF03419.8 AIO01958.1 - 0.87 8.5 5.5 0.18 10.8 1.1 1.8 2 0 0 2 2 2 0 Sporulation factor SpoIIGA SNARE PF05739.14 AIO01959.1 - 8.5e-17 60.5 1.3 8.5e-17 60.5 0.9 3.0 3 0 0 3 3 3 1 SNARE domain Syntaxin PF00804.20 AIO01959.1 - 0.0002 21.4 2.5 0.0002 21.4 1.7 2.5 2 1 0 2 2 2 1 Syntaxin Syntaxin_2 PF14523.1 AIO01959.1 - 0.062 13.3 11.0 0.026 14.5 1.8 2.4 2 0 0 2 2 2 0 Syntaxin-like protein MCPsignal PF00015.16 AIO01959.1 - 0.31 10.5 10.0 0.024 14.1 1.8 2.1 1 1 1 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain DUF1664 PF07889.7 AIO01959.1 - 1.7 8.4 6.1 1.7 8.4 0.3 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Transposase_22 PF02994.9 AIO01959.1 - 4 5.8 14.0 3.1 6.1 8.0 1.7 1 1 1 2 2 2 0 L1 transposable element DUF4058 PF13267.1 AIO01961.1 - 0.065 12.3 2.0 0.1 11.7 0.8 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF4058) FYVE PF01363.16 AIO01962.1 - 2.2e-19 69.1 7.1 3.5e-19 68.4 4.9 1.3 1 0 0 1 1 1 1 FYVE zinc finger OrfB_Zn_ribbon PF07282.6 AIO01962.1 - 2.3 7.9 6.5 5.6 6.6 4.5 1.6 1 0 0 1 1 1 0 Putative transposase DNA-binding domain SMC_N PF02463.14 AIO01963.1 - 2.8e-57 193.4 0.0 3e-56 190.1 0.0 2.0 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 AIO01963.1 - 1.3e-25 89.7 0.0 1.1e-24 86.7 0.0 2.7 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.1 AIO01963.1 - 5.3e-15 56.1 0.0 4.6e-07 30.0 0.0 2.2 2 0 0 2 2 2 2 AAA domain AAA_23 PF13476.1 AIO01963.1 - 1.1e-10 42.2 35.9 8.8e-08 32.7 14.2 4.7 2 1 0 2 2 2 1 AAA domain AAA_29 PF13555.1 AIO01963.1 - 8.3e-07 28.4 0.0 1.7e-06 27.4 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_15 PF13175.1 AIO01963.1 - 0.0033 16.5 0.0 0.0073 15.4 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain OmpH PF03938.9 AIO01963.1 - 0.049 13.5 0.2 0.049 13.5 0.1 7.1 3 2 0 4 4 4 0 Outer membrane protein (OmpH-like) ABC_tran PF00005.22 AIO01963.1 - 0.069 13.4 0.0 0.069 13.4 0.0 5.3 4 2 1 5 5 5 0 ABC transporter NIF PF03031.13 AIO01964.1 - 1.4e-29 102.8 0.0 2.7e-29 101.8 0.0 1.5 1 1 0 1 1 1 1 NLI interacting factor-like phosphatase KH_1 PF00013.24 AIO01966.1 - 4.9e-07 29.2 1.3 1.3e-06 27.9 0.9 1.7 1 0 0 1 1 1 1 KH domain DUF2497 PF10691.4 AIO01967.1 - 0.014 15.3 0.3 0.014 15.3 0.2 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF2497) Baculo_PEP_C PF04513.7 AIO01967.1 - 0.027 14.2 3.7 0.67 9.7 0.5 2.9 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Hira PF07569.6 AIO01967.1 - 0.048 12.8 2.2 0.079 12.1 1.5 1.2 1 0 0 1 1 1 0 TUP1-like enhancer of split Fib_alpha PF08702.5 AIO01967.1 - 0.13 12.3 5.5 3.8 7.6 0.1 2.6 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family DUF2229 PF09989.4 AIO01967.1 - 1.7 8.0 4.9 4.6 6.6 0.2 2.2 2 0 0 2 2 2 0 CoA enzyme activase uncharacterised domain (DUF2229) Apolipoprotein PF01442.13 AIO01967.1 - 3.1 7.2 25.5 26 4.2 17.7 2.5 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain UPF0242 PF06785.6 AIO01967.1 - 4.8 5.7 12.5 0.2 10.2 4.3 1.7 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) CRAL_TRIO PF00650.15 AIO01968.1 - 9.4e-26 90.2 0.1 1.5e-25 89.5 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 AIO01968.1 - 4.8e-06 26.6 1.7 5.4e-06 26.4 0.2 1.8 2 0 0 2 2 2 1 CRAL/TRIO, N-terminal domain FUSC_2 PF13515.1 AIO01969.1 - 1.3e-07 31.5 6.0 1.3e-07 31.5 4.1 2.5 2 1 0 2 2 2 1 Fusaric acid resistance protein-like FUSC PF04632.7 AIO01969.1 - 4.7e-06 25.3 0.3 9.1e-06 24.3 0.2 1.5 1 0 0 1 1 1 1 Fusaric acid resistance protein family XPG_I_2 PF12813.2 AIO01970.1 - 4.7e-32 111.4 0.1 7.4e-32 110.7 0.1 1.3 1 0 0 1 1 1 1 XPG domain containing XPG_I PF00867.13 AIO01970.1 - 2.6e-22 78.6 0.1 6.5e-22 77.3 0.1 1.7 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.12 AIO01970.1 - 3.9e-20 71.9 0.0 8.3e-20 70.9 0.0 1.5 1 0 0 1 1 1 1 XPG N-terminal domain DUF4347 PF14252.1 AIO01970.1 - 0.4 10.1 4.5 1.1 8.7 0.3 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4347) Methyltransf_23 PF13489.1 AIO01971.1 - 7.3e-23 81.0 0.0 1.1e-22 80.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 AIO01971.1 - 0.0002 21.7 0.0 0.0019 18.6 0.0 2.5 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 AIO01971.1 - 0.028 14.9 0.0 0.097 13.2 0.0 2.0 2 1 0 2 2 2 0 Methyltransferase domain Methyltransf_31 PF13847.1 AIO01971.1 - 0.053 13.1 0.0 0.23 11.0 0.0 2.0 3 0 0 3 3 3 0 Methyltransferase domain Pro_isomerase PF00160.16 AIO01972.1 - 1.1e-28 100.4 0.0 2.1e-28 99.4 0.0 1.5 2 0 0 2 2 2 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD NifU_N PF01592.11 AIO01973.1 - 4.4e-48 162.3 0.1 5.7e-48 162.0 0.0 1.1 1 0 0 1 1 1 1 NifU-like N terminal domain IF2_N PF04760.10 AIO01973.1 - 0.12 12.0 0.1 0.22 11.2 0.1 1.4 1 0 0 1 1 1 0 Translation initiation factor IF-2, N-terminal region MatE PF01554.13 AIO01974.1 - 8.2e-31 106.8 28.3 6.6e-17 61.6 7.9 3.3 3 0 0 3 3 3 3 MatE NDUF_B7 PF05676.8 AIO01977.1 - 1.6e-08 33.7 0.3 2.6e-08 33.1 0.2 1.3 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) Ribul_P_3_epim PF00834.14 AIO01978.1 - 3.4e-51 173.2 0.0 4e-51 172.9 0.0 1.0 1 0 0 1 1 1 1 Ribulose-phosphate 3 epimerase family PEX11 PF05648.9 AIO01979.1 - 4.2e-10 39.2 0.0 5.3e-10 38.9 0.0 1.0 1 0 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) DUF3329 PF11808.3 AIO01979.1 - 0.08 13.0 0.0 0.19 11.8 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3329) PEX11 PF05648.9 AIO01980.1 - 5.2e-16 58.5 0.1 1.7e-15 56.9 0.0 1.7 1 1 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) Pox_F12L PF03337.8 AIO01984.1 - 0.098 10.5 0.0 0.13 10.0 0.0 1.1 1 0 0 1 1 1 0 Poxvirus F12L protein Cullin PF00888.17 AIO01985.1 - 4.1e-20 71.8 0.0 6.8e-20 71.1 0.0 1.3 1 0 0 1 1 1 1 Cullin family Ribosomal_L18e PF00828.14 AIO01986.1 - 8.2e-33 113.5 1.9 9.5e-33 113.3 1.3 1.0 1 0 0 1 1 1 1 Ribosomal protein L18e/L15 GHMP_kinases_N PF00288.21 AIO01987.1 - 1.6 8.8 5.3 0.38 10.8 0.3 2.4 2 0 0 2 2 2 0 GHMP kinases N terminal domain Ribosomal_L18e PF00828.14 AIO01988.1 - 8.2e-33 113.5 1.9 9.5e-33 113.3 1.3 1.0 1 0 0 1 1 1 1 Ribosomal protein L18e/L15 Ribosomal_L14 PF00238.14 AIO01989.1 - 9.7e-37 125.4 0.0 1.1e-36 125.2 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e Ribosomal_L14 PF00238.14 AIO01990.1 - 9.7e-37 125.4 0.0 1.1e-36 125.2 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e Cucumo_2B PF03263.8 AIO01992.1 - 0.075 13.3 0.6 0.2 11.9 0.1 2.0 2 0 0 2 2 2 0 Cucumovirus protein 2B TMF_TATA_bd PF12325.3 AIO01992.1 - 0.28 10.9 5.2 1.4 8.6 3.4 2.4 1 1 0 1 1 1 0 TATA element modulatory factor 1 TATA binding Cep57_CLD_2 PF14197.1 AIO01992.1 - 1.8 8.5 16.3 0.039 13.9 3.1 3.4 3 0 0 3 3 3 0 Centrosome localisation domain of PPC89 TSC22 PF01166.13 AIO01992.1 - 3 7.8 6.6 2.4 8.1 0.4 3.4 3 1 1 4 4 4 0 TSC-22/dip/bun family SET PF00856.23 AIO01993.1 - 0.00093 19.5 0.0 0.013 15.8 0.0 2.2 1 1 0 1 1 1 1 SET domain Proteasome PF00227.21 AIO01994.1 - 7.3e-48 162.3 0.3 8.7e-48 162.1 0.2 1.1 1 0 0 1 1 1 1 Proteasome subunit Pr_beta_C PF12465.3 AIO01994.1 - 0.00029 20.0 0.2 0.00029 20.0 0.1 1.9 2 0 0 2 2 2 1 Proteasome beta subunits C terminal DUF1375 PF07119.7 AIO01994.1 - 0.025 14.4 0.0 0.054 13.3 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1375) Ribosomal_S17 PF00366.15 AIO01995.1 - 7.8e-15 54.6 0.6 7.8e-15 54.6 0.4 1.7 2 0 0 2 2 2 1 Ribosomal protein S17 Cpn60_TCP1 PF00118.19 AIO01996.1 - 2.2e-147 491.5 1.3 2.6e-147 491.3 0.9 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family NDK PF00334.14 AIO01997.1 - 1.6e-30 105.6 0.0 9.2e-28 96.7 0.0 2.3 2 1 0 2 2 2 2 Nucleoside diphosphate kinase TPT PF03151.11 AIO01997.1 - 0.23 11.0 2.1 3.2 7.3 0.1 2.1 1 1 1 2 2 2 0 Triose-phosphate Transporter family WD40 PF00400.27 AIO01998.1 - 6.7e-39 130.4 18.9 4.2e-10 39.1 0.0 7.4 7 0 0 7 7 7 6 WD domain, G-beta repeat Sof1 PF04158.9 AIO01998.1 - 3.1e-09 36.7 8.2 5.6e-09 35.9 5.7 1.4 1 0 0 1 1 1 1 Sof1-like domain eIF2A PF08662.6 AIO01998.1 - 0.001 18.7 0.1 0.0036 17.0 0.0 1.9 2 1 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 AIO01998.1 - 0.011 13.9 1.9 3.5 5.6 0.1 3.4 2 2 1 3 3 3 0 Nucleoporin Nup120/160 EF-hand_7 PF13499.1 AIO01999.1 - 2.6e-11 43.5 0.2 3e-09 36.8 0.3 2.3 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.27 AIO01999.1 - 3.3e-11 41.6 1.1 2.9e-08 32.4 0.0 4.0 4 1 1 5 5 5 1 EF hand EF-hand_6 PF13405.1 AIO01999.1 - 6.3e-10 38.1 0.0 8.2e-06 25.2 0.0 3.4 3 0 0 3 3 3 2 EF-hand domain EF-hand_8 PF13833.1 AIO01999.1 - 3.4e-09 36.1 1.2 0.0031 17.0 0.1 3.4 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_5 PF13202.1 AIO01999.1 - 3.5e-05 22.9 3.2 4e-05 22.7 0.0 2.6 3 0 0 3 3 3 1 EF hand EF-hand_9 PF14658.1 AIO01999.1 - 0.0012 18.6 0.1 0.22 11.4 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain UPF0154 PF03672.8 AIO01999.1 - 0.012 15.1 0.0 0.3 10.7 0.0 2.1 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0154) Baculo_p48 PF04878.8 AIO01999.1 - 0.061 12.2 0.1 0.076 11.9 0.0 1.2 1 0 0 1 1 1 0 Baculovirus P48 protein SHIPPO-rpt PF07004.7 AIO02002.1 - 4.4e-18 65.1 37.4 0.18 12.7 0.1 9.8 9 0 0 9 9 9 8 Sperm-tail PG-rich repeat UNC-50 PF05216.8 AIO02003.1 - 4.5e-63 212.5 8.1 5.3e-63 212.3 5.6 1.0 1 0 0 1 1 1 1 UNC-50 family INCENP_N PF12178.3 AIO02004.1 - 1.2e-16 59.9 0.3 2.3e-16 59.0 0.2 1.5 1 0 0 1 1 1 1 Chromosome passenger complex (CPC) protein INCENP N terminal PROCN PF08083.6 AIO02005.1 - 6.4e-167 555.1 1.3 6.4e-167 555.1 0.9 1.6 2 0 0 2 2 2 1 PROCN (NUC071) domain PRP8_domainIV PF12134.3 AIO02005.1 - 2.9e-95 317.9 0.0 4.7e-95 317.3 0.0 1.3 1 0 0 1 1 1 1 PRP8 domain IV core U6-snRNA_bdg PF10596.4 AIO02005.1 - 5.1e-70 233.9 0.0 1.1e-69 232.8 0.0 1.6 1 0 0 1 1 1 1 U6-snRNA interacting domain of PrP8 PRO8NT PF08082.6 AIO02005.1 - 1.2e-59 200.3 0.0 3.4e-59 198.8 0.0 1.9 1 0 0 1 1 1 1 PRO8NT (NUC069), PrP8 N-terminal domain U5_2-snRNA_bdg PF10597.4 AIO02005.1 - 2.1e-57 192.5 0.1 6.9e-57 190.8 0.1 1.9 1 0 0 1 1 1 1 U5-snRNA binding site 2 of PrP8 PROCT PF08084.6 AIO02005.1 - 7.8e-38 129.0 0.0 2.6e-37 127.3 0.0 1.9 2 0 0 2 2 2 1 PROCT (NUC072) domain RRM_4 PF10598.4 AIO02005.1 - 9e-36 121.6 0.0 2.3e-35 120.3 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif of the spliceosomal PrP8 zf-MIZ PF02891.15 AIO02006.1 - 2e-18 65.6 1.3 3.8e-18 64.7 0.9 1.5 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger zf-Nse PF11789.3 AIO02006.1 - 0.0014 18.1 0.1 0.0029 17.0 0.1 1.5 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit Mito_carr PF00153.22 AIO02008.1 - 7.9e-43 144.0 0.8 8.6e-21 73.4 0.0 2.1 2 0 0 2 2 2 2 Mitochondrial carrier protein HECT PF00632.20 AIO02009.1 - 1.7e-53 181.8 0.0 3.3e-53 180.8 0.0 1.5 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Pkinase PF00069.20 AIO02009.1 - 1.6e-50 171.7 0.0 3.5e-50 170.5 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AIO02009.1 - 1.1e-31 109.8 0.0 2.1e-31 108.9 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase TPR_11 PF13414.1 AIO02009.1 - 7.1e-18 64.0 6.6 2.2e-15 56.0 0.5 3.4 2 1 2 4 4 4 3 TPR repeat TPR_1 PF00515.23 AIO02009.1 - 3e-13 48.7 1.7 5.1e-06 25.8 0.0 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.12 AIO02009.1 - 4.3e-13 48.1 4.1 2.9e-05 23.6 0.1 4.2 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_8 PF13181.1 AIO02009.1 - 2.9e-07 29.7 1.1 0.67 9.8 0.0 4.0 3 0 0 3 3 3 3 Tetratricopeptide repeat Kinase-like PF14531.1 AIO02009.1 - 1.7e-05 23.9 0.1 7e-05 21.9 0.0 2.1 2 0 0 2 2 2 1 Kinase-like TPR_19 PF14559.1 AIO02009.1 - 2.2e-05 24.6 1.0 0.18 12.1 0.0 3.6 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.1 AIO02009.1 - 0.00022 21.1 0.2 0.12 12.6 0.0 3.1 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.1 AIO02009.1 - 0.00031 20.3 0.6 0.021 14.6 0.0 3.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.1 AIO02009.1 - 0.0046 17.4 10.1 0.063 13.9 0.1 4.1 4 0 0 4 4 2 2 Tetratricopeptide repeat APH PF01636.18 AIO02009.1 - 0.0054 16.4 0.0 0.0054 16.4 0.0 2.9 3 0 0 3 3 3 1 Phosphotransferase enzyme family RIO1 PF01163.17 AIO02009.1 - 0.0066 15.8 0.0 0.024 13.9 0.0 1.9 1 0 0 1 1 1 1 RIO1 family TPR_6 PF13174.1 AIO02009.1 - 0.013 15.9 0.2 2.5 8.7 0.0 3.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_16 PF13432.1 AIO02009.1 - 0.02 15.5 13.2 0.036 14.7 0.0 3.6 3 0 0 3 3 2 0 Tetratricopeptide repeat tRNA-synt_2c PF01411.14 AIO02009.1 - 0.028 12.6 2.2 0.06 11.6 1.5 1.4 1 0 0 1 1 1 0 tRNA synthetases class II (A) TPR_12 PF13424.1 AIO02009.1 - 0.031 14.2 8.2 1.2 9.1 0.1 3.9 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_9 PF13371.1 AIO02009.1 - 0.063 13.1 5.7 4.2 7.3 0.0 4.1 3 1 1 4 4 3 0 Tetratricopeptide repeat AAA_13 PF13166.1 AIO02009.1 - 2.4 6.5 27.1 0.25 9.7 8.2 2.2 2 0 0 2 2 2 0 AAA domain EMP24_GP25L PF01105.19 AIO02009.1 - 4.7 6.8 8.6 0.18 11.5 0.7 2.3 2 1 0 2 2 2 0 emp24/gp25L/p24 family/GOLD Pkinase PF00069.20 AIO02010.1 - 6.1e-69 232.0 0.0 7.2e-69 231.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AIO02010.1 - 2.6e-33 115.2 0.0 3.3e-33 114.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 AIO02010.1 - 3.7e-05 22.8 0.0 4.9e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_C PF00433.19 AIO02010.1 - 0.021 15.3 0.2 0.021 15.3 0.1 1.8 2 0 0 2 2 2 0 Protein kinase C terminal domain POR PF01558.13 AIO02010.1 - 0.12 12.2 0.0 0.2 11.5 0.0 1.3 1 0 0 1 1 1 0 Pyruvate ferredoxin/flavodoxin oxidoreductase Abhydrolase_5 PF12695.2 AIO02011.1 - 1.2e-22 80.1 0.1 5.5e-22 78.0 0.1 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 AIO02011.1 - 1.3e-15 57.8 0.5 3.5e-15 56.5 0.3 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 AIO02011.1 - 1.4e-06 27.9 0.0 0.05 13.0 0.0 2.3 2 0 0 2 2 2 2 Phospholipase/Carboxylesterase Peptidase_S9 PF00326.16 AIO02011.1 - 4.9e-06 25.9 0.0 3.3e-05 23.1 0.0 2.0 1 1 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_3 PF07859.8 AIO02011.1 - 5.9e-06 26.0 0.3 9.5e-06 25.3 0.2 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S15 PF02129.13 AIO02011.1 - 0.00013 21.4 0.0 0.21 10.9 0.0 2.1 2 0 0 2 2 2 2 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_1 PF00561.15 AIO02011.1 - 0.0002 20.9 0.0 0.063 12.8 0.0 2.2 1 1 1 2 2 2 2 alpha/beta hydrolase fold BAAT_C PF08840.6 AIO02011.1 - 0.00028 20.6 0.0 0.00046 19.9 0.0 1.3 1 0 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal AXE1 PF05448.7 AIO02011.1 - 0.00045 18.8 0.2 0.008 14.7 0.0 2.4 2 1 1 3 3 3 1 Acetyl xylan esterase (AXE1) DLH PF01738.13 AIO02011.1 - 0.0014 18.0 0.0 0.034 13.4 0.0 2.1 1 1 1 2 2 2 1 Dienelactone hydrolase family Hydrolase_4 PF12146.3 AIO02011.1 - 0.004 16.9 0.0 0.0088 15.8 0.0 1.5 1 0 0 1 1 1 1 Putative lysophospholipase DUF1100 PF06500.6 AIO02011.1 - 0.035 12.6 0.0 0.045 12.3 0.0 1.1 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1100) PGAP1 PF07819.8 AIO02011.1 - 0.068 12.7 0.1 0.14 11.7 0.0 1.6 1 1 0 1 1 1 0 PGAP1-like protein FSH1 PF03959.8 AIO02011.1 - 0.093 12.1 0.0 0.16 11.4 0.0 1.4 1 1 0 1 1 1 0 Serine hydrolase (FSH1) DEAD PF00270.24 AIO02012.1 - 2e-35 121.7 0.0 7.5e-35 119.9 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 AIO02012.1 - 2.9e-22 78.3 0.0 1e-21 76.5 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF4217 PF13959.1 AIO02012.1 - 7.6e-17 60.6 0.0 2.1e-16 59.2 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.10 AIO02012.1 - 0.00012 22.0 0.0 0.0003 20.6 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DnaJ PF00226.26 AIO02013.1 - 8e-16 57.5 0.0 4e-15 55.2 0.0 2.1 1 1 0 1 1 1 1 DnaJ domain HDOD PF08668.7 AIO02013.1 - 0.043 13.0 0.4 0.066 12.4 0.3 1.2 1 0 0 1 1 1 0 HDOD domain FadA PF09403.5 AIO02013.1 - 0.16 11.9 4.2 0.31 11.0 2.9 1.4 1 0 0 1 1 1 0 Adhesion protein FadA TORC_N PF12884.2 AIO02013.1 - 0.23 12.0 8.4 0.78 10.3 5.8 1.9 1 0 0 1 1 1 0 Transducer of regulated CREB activity, N terminus TFIIA PF03153.8 AIO02013.1 - 1.7 8.4 10.6 2.2 8.1 7.4 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit OmpH PF03938.9 AIO02013.1 - 2.4 8.0 11.3 3.6 7.4 7.8 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Pkinase PF00069.20 AIO02015.1 - 4.1e-39 134.3 0.0 2.1e-38 131.9 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AIO02015.1 - 2.6e-22 79.1 0.0 4.1e-21 75.2 0.0 2.2 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 AIO02015.1 - 9.6e-09 34.6 0.0 1.7e-08 33.7 0.0 1.3 1 0 0 1 1 1 1 Kinase-like IL4 PF00727.13 AIO02015.1 - 0.12 12.2 0.0 0.26 11.1 0.0 1.5 1 0 0 1 1 1 0 Interleukin 4 Seadorna_VP7 PF07387.6 AIO02015.1 - 0.5 9.1 0.1 0.79 8.4 0.1 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 zf-RING_4 PF14570.1 AIO02015.1 - 1.9 8.1 17.9 3.7 7.2 12.4 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain RIIa PF02197.12 AIO02016.1 - 2.6e-10 39.5 0.1 8.2e-10 37.9 0.0 1.9 2 0 0 2 2 2 1 Regulatory subunit of type II PKA R-subunit EF-hand_6 PF13405.1 AIO02016.1 - 5e-05 22.8 0.3 0.27 11.2 0.0 3.1 3 0 0 3 3 3 2 EF-hand domain EF-hand_7 PF13499.1 AIO02016.1 - 0.00027 21.0 0.0 0.0023 18.0 0.0 2.3 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.27 AIO02016.1 - 0.0084 15.3 0.1 1.9 7.9 0.0 3.3 3 0 0 3 3 3 1 EF hand TPR_11 PF13414.1 AIO02017.1 - 1.4e-14 53.4 11.7 0.00013 21.5 0.1 4.9 3 2 0 4 4 4 4 TPR repeat TPR_2 PF07719.12 AIO02017.1 - 1.7e-14 52.5 10.9 0.016 15.1 0.0 6.8 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_19 PF14559.1 AIO02017.1 - 2.1e-11 44.0 11.1 0.008 16.4 0.0 4.7 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_14 PF13428.1 AIO02017.1 - 3.5e-09 36.4 16.2 0.00048 20.5 0.1 6.6 3 3 4 7 7 7 2 Tetratricopeptide repeat TPR_16 PF13432.1 AIO02017.1 - 3.7e-09 36.9 15.7 0.0011 19.5 0.1 4.8 3 1 3 6 6 6 3 Tetratricopeptide repeat TPR_1 PF00515.23 AIO02017.1 - 7.7e-07 28.4 8.9 0.58 9.8 1.2 5.9 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_12 PF13424.1 AIO02017.1 - 1.6e-06 27.9 17.8 0.24 11.3 0.1 5.7 2 2 4 6 6 6 5 Tetratricopeptide repeat TPR_4 PF07721.9 AIO02017.1 - 4.2e-05 23.5 6.8 0.027 14.8 0.5 4.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.1 AIO02017.1 - 7.9e-05 22.1 14.0 0.028 14.2 0.0 5.4 5 1 0 5 5 5 2 Tetratricopeptide repeat TPR_15 PF13429.1 AIO02017.1 - 8.1e-05 21.8 3.5 0.011 14.7 0.2 3.2 1 1 0 2 2 2 2 Tetratricopeptide repeat TPR_17 PF13431.1 AIO02017.1 - 0.00014 21.7 6.7 0.45 10.8 0.0 5.0 5 1 0 5 5 4 2 Tetratricopeptide repeat TPR_6 PF13174.1 AIO02017.1 - 0.0002 21.6 6.9 0.22 12.0 0.0 5.5 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_8 PF13181.1 AIO02017.1 - 0.00035 20.1 3.9 4.2 7.3 2.0 5.5 5 1 1 6 6 6 1 Tetratricopeptide repeat NODP PF07684.7 AIO02017.1 - 0.013 15.0 0.0 6.9 6.3 0.0 2.6 2 0 0 2 2 2 0 NOTCH protein CbiX PF01903.12 AIO02017.1 - 0.093 12.8 0.1 0.28 11.3 0.0 1.8 2 0 0 2 2 2 0 CbiX TPR_21 PF09976.4 AIO02017.1 - 0.91 9.4 7.0 2.4 8.1 0.2 3.3 1 1 2 3 3 3 0 Tetratricopeptide repeat MIT PF04212.13 AIO02017.1 - 1.2 9.1 8.2 0.4 10.5 0.5 3.6 4 0 0 4 4 4 0 MIT (microtubule interacting and transport) domain SF3b10 PF07189.6 AIO02019.1 - 1e-14 54.0 0.0 1.1e-14 53.9 0.0 1.0 1 0 0 1 1 1 1 Splicing factor 3B subunit 10 (SF3b10) SseB PF07179.7 AIO02020.1 - 0.0038 17.0 0.0 1.6 8.5 0.0 2.5 2 0 0 2 2 2 2 SseB protein N-terminal domain HD_3 PF13023.1 AIO02021.1 - 2.3e-38 131.5 0.0 2.7e-38 131.3 0.0 1.1 1 0 0 1 1 1 1 HD domain HD PF01966.17 AIO02021.1 - 2.1e-06 27.7 0.0 3.5e-06 27.0 0.0 1.4 1 0 0 1 1 1 1 HD domain RRM_1 PF00076.17 AIO02024.1 - 2.1e-72 238.7 0.0 1.4e-17 63.0 0.0 4.3 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 AIO02024.1 - 1e-51 172.8 0.0 5.5e-13 48.7 0.0 4.3 4 0 0 4 4 4 4 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) PABP PF00658.13 AIO02024.1 - 5.7e-28 96.3 0.2 1.1e-27 95.4 0.1 1.5 1 0 0 1 1 1 1 Poly-adenylate binding protein, unique domain RRM_5 PF13893.1 AIO02024.1 - 3.7e-26 90.7 0.1 5e-08 32.6 0.0 4.3 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 AIO02024.1 - 3e-08 33.4 5.6 0.68 9.8 0.4 4.4 3 1 1 4 4 4 4 RNA binding motif Nup35_RRM_2 PF14605.1 AIO02024.1 - 1.7e-05 24.4 0.0 0.79 9.5 0.0 4.1 4 0 0 4 4 4 2 Nup53/35/40-type RNA recognition motif Limkain-b1 PF11608.3 AIO02024.1 - 0.016 14.9 2.9 0.15 11.7 0.1 3.4 2 1 1 3 3 3 0 Limkain b1 FliG_M PF14841.1 AIO02024.1 - 0.03 14.3 0.1 4.3 7.4 0.0 2.6 1 1 1 2 2 2 0 FliG middle domain TB2_DP1_HVA22 PF03134.14 AIO02025.1 - 0.25 11.1 1.7 0.82 9.4 1.2 1.9 1 1 0 1 1 1 0 TB2/DP1, HVA22 family GTP_EFTU PF00009.22 AIO02026.1 - 6.9e-44 149.5 0.0 9.4e-42 142.5 0.0 2.3 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 AIO02026.1 - 2.1e-08 34.2 0.3 5.9e-08 32.7 0.1 1.9 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain MMR_HSR1 PF01926.18 AIO02026.1 - 0.0011 18.9 0.0 0.0022 17.9 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase G-alpha PF00503.15 AIO02026.1 - 0.038 12.6 0.2 0.059 12.0 0.2 1.2 1 0 0 1 1 1 0 G-protein alpha subunit DUF2009 PF09418.5 AIO02027.1 - 3.9e-208 691.8 0.0 4.4e-208 691.6 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2009) RNA_pol_Rpc4 PF05132.9 AIO02028.1 - 3.6e-07 30.2 0.0 9.8e-07 28.8 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase III RPC4 BBS1 PF14779.1 AIO02029.1 - 1.5e-57 194.5 0.0 2.5e-57 193.7 0.0 1.3 1 0 0 1 1 1 1 Ciliary BBSome complex subunit 1 PHTB1_N PF14727.1 AIO02029.1 - 0.0018 17.3 0.0 0.018 13.9 0.0 2.5 3 0 0 3 3 3 1 PTHB1 N-terminus BBS2_Mid PF14783.1 AIO02029.1 - 0.014 15.1 0.0 3.2 7.5 0.0 3.2 2 1 0 3 3 3 0 Ciliary BBSome complex subunit 2, middle region VMA21 PF09446.5 AIO02030.1 - 0.0046 16.8 7.5 0.007 16.2 5.2 1.3 1 0 0 1 1 1 1 VMA21-like domain BPD_transp_1 PF00528.17 AIO02030.1 - 0.071 12.6 2.9 0.11 12.0 2.0 1.2 1 0 0 1 1 1 0 Binding-protein-dependent transport system inner membrane component OSTMP1 PF09777.4 AIO02030.1 - 0.14 11.3 0.9 0.27 10.3 0.6 1.4 1 0 0 1 1 1 0 Osteopetrosis-associated transmembrane protein 1 precursor SOG2 PF10428.4 AIO02030.1 - 1.4 7.4 6.3 1.8 7.1 4.3 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein Syja_N PF02383.13 AIO02032.1 - 6.3e-26 90.8 0.0 7.4e-24 84.0 0.0 2.2 2 0 0 2 2 2 2 SacI homology domain Fijivirus_P9-2 PF06837.6 AIO02032.1 - 6.7 5.7 5.6 11 5.1 3.9 1.2 1 0 0 1 1 1 0 Fijivirus P9-2 protein Methyltransf_23 PF13489.1 AIO02034.1 - 5.3e-20 71.7 0.0 7.4e-20 71.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 AIO02034.1 - 2.2e-18 66.3 0.0 1.1e-17 63.9 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 AIO02034.1 - 9.5e-18 64.4 0.0 1.5e-17 63.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 AIO02034.1 - 3.7e-13 50.0 0.0 5.5e-13 49.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 AIO02034.1 - 1.3e-12 47.9 0.1 4.2e-12 46.4 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 AIO02034.1 - 2.1e-09 37.6 0.0 4.2e-09 36.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 AIO02034.1 - 2.9e-09 36.9 0.0 7e-09 35.7 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain CMAS PF02353.15 AIO02034.1 - 5.4e-08 32.2 0.0 1.7e-07 30.5 0.0 1.7 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase PrmA PF06325.8 AIO02034.1 - 2.3e-06 26.9 0.1 3.4e-06 26.4 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) NodS PF05401.6 AIO02034.1 - 5e-06 26.0 0.3 2.8e-05 23.5 0.2 1.9 1 1 0 1 1 1 1 Nodulation protein S (NodS) Methyltransf_32 PF13679.1 AIO02034.1 - 7.2e-06 25.7 0.0 1e-05 25.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 AIO02034.1 - 2.4e-05 23.7 0.1 4.4e-05 22.9 0.1 1.5 1 1 0 1 1 1 1 Methyltransferase small domain Pox_MCEL PF03291.11 AIO02034.1 - 0.00021 20.2 0.0 0.00034 19.6 0.0 1.2 1 0 0 1 1 1 1 mRNA capping enzyme Ubie_methyltran PF01209.13 AIO02034.1 - 0.0009 18.4 0.0 0.0015 17.6 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family PCMT PF01135.14 AIO02034.1 - 0.0033 16.9 0.1 0.005 16.4 0.1 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MetW PF07021.7 AIO02034.1 - 0.0079 15.5 0.9 0.16 11.2 0.0 2.4 3 0 0 3 3 3 1 Methionine biosynthesis protein MetW TPMT PF05724.6 AIO02034.1 - 0.02 14.3 0.0 0.032 13.6 0.0 1.2 1 0 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) TehB PF03848.9 AIO02034.1 - 0.023 13.8 0.0 0.071 12.2 0.0 1.8 1 1 0 1 1 1 0 Tellurite resistance protein TehB RrnaAD PF00398.15 AIO02034.1 - 0.083 11.9 0.0 0.13 11.2 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase FYVE PF01363.16 AIO02035.1 - 1.6e-16 59.9 14.0 1.3e-15 57.0 5.1 2.5 2 0 0 2 2 2 2 FYVE zinc finger DUF572 PF04502.8 AIO02035.1 - 0.87 8.7 28.1 1.3 8.2 19.5 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) POP1 PF06978.6 AIO02035.1 - 1.9 8.0 24.3 4 7.0 16.9 1.6 1 0 0 1 1 1 0 Ribonucleases P/MRP protein subunit POP1 GAGA_bind PF06217.7 AIO02035.1 - 3 7.7 20.1 4.3 7.2 14.0 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family Asp-B-Hydro_N PF05279.6 AIO02035.1 - 5 6.8 33.4 6.7 6.4 23.2 1.2 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region DUF4586 PF15239.1 AIO02035.1 - 5 6.5 7.9 0.25 10.8 0.9 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4586) zf-HIT PF04438.11 AIO02035.1 - 7.8 6.2 15.2 6.4 6.5 1.7 2.6 2 0 0 2 2 2 0 HIT zinc finger GAS PF13851.1 AIO02037.1 - 1 8.4 49.8 0.02 14.0 8.5 4.0 1 1 2 4 4 4 0 Growth-arrest specific micro-tubule binding bZIP_1 PF00170.16 AIO02037.1 - 3.8 7.5 27.2 0.18 11.7 4.5 4.5 4 0 0 4 4 4 0 bZIP transcription factor US22 PF02393.11 AIO02039.1 - 0.062 13.3 0.0 0.11 12.5 0.0 1.3 1 0 0 1 1 1 0 US22 like Cyclin_C PF02984.14 AIO02040.1 - 0.049 13.5 1.4 0.074 12.9 0.5 1.7 1 1 1 2 2 2 0 Cyclin, C-terminal domain Col_cuticle_N PF01484.12 AIO02040.1 - 6.6 6.4 8.2 2.1 8.0 0.4 2.4 2 0 0 2 2 2 0 Nematode cuticle collagen N-terminal domain Hydrolase_6 PF13344.1 AIO02041.1 - 2.3e-24 85.1 0.0 4.6e-24 84.2 0.0 1.5 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 AIO02041.1 - 1.2e-12 47.3 0.0 2.7e-12 46.1 0.0 1.6 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.21 AIO02041.1 - 0.0014 19.1 0.1 1.8 8.9 0.0 2.6 3 0 0 3 3 3 2 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 AIO02041.1 - 0.01 16.0 0.3 2.5 8.2 0.0 2.9 3 1 0 3 3 3 0 Haloacid dehalogenase-like hydrolase PIH1 PF08190.7 AIO02042.1 - 3.7e-121 404.5 0.0 3.7e-121 404.5 0.0 2.2 3 0 0 3 3 3 1 pre-RNA processing PIH1/Nop17 PGAP1 PF07819.8 AIO02044.1 - 3.9e-12 46.2 0.0 1.2e-05 25.0 0.0 2.4 2 0 0 2 2 2 2 PGAP1-like protein Abhydrolase_6 PF12697.2 AIO02044.1 - 2.2e-06 27.7 0.1 0.00027 20.8 0.1 2.9 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 AIO02044.1 - 0.0082 15.8 0.3 0.22 11.2 0.2 2.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF1744 PF08490.7 AIO02045.1 - 3.5e-47 160.8 0.0 2.2e-46 158.2 0.0 2.1 1 1 0 1 1 1 1 Domain of unknown function (DUF1744) DNA_pol_B_exo1 PF03104.14 AIO02045.1 - 3.6e-47 160.8 0.1 6.4e-47 159.9 0.1 1.4 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain DNA_pol_B PF00136.16 AIO02045.1 - 4.3e-19 68.6 0.0 2.8e-16 59.3 0.0 3.3 2 1 0 2 2 2 2 DNA polymerase family B DNA_pol_B_exo2 PF10108.4 AIO02045.1 - 2.7e-10 40.1 0.4 5.7e-09 35.8 0.3 2.5 1 1 0 1 1 1 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB RNase_H_2 PF13482.1 AIO02045.1 - 5.3e-08 32.8 0.4 2.1e-07 30.8 0.1 2.2 2 1 0 2 2 2 1 RNase_H superfamily zf-DNA_Pol PF08996.5 AIO02045.1 - 0.0051 16.1 1.1 0.014 14.7 0.8 1.7 1 0 0 1 1 1 1 DNA Polymerase alpha zinc finger YopE_N PF09020.5 AIO02045.1 - 0.15 12.0 0.0 0.5 10.4 0.0 1.8 2 0 0 2 2 2 0 YopE, N terminal zf-3CxxC PF13695.1 AIO02046.1 - 1.6e-07 31.4 4.2 1.9e-07 31.1 2.9 1.1 1 0 0 1 1 1 1 Zinc-binding domain zinc_ribbon_5 PF13719.1 AIO02046.1 - 0.43 10.2 9.0 0.1 12.2 1.6 2.3 2 0 0 2 2 2 0 zinc-ribbon domain zinc_ribbon_4 PF13717.1 AIO02046.1 - 0.81 9.4 9.3 0.13 12.0 1.8 2.2 2 0 0 2 2 2 0 zinc-ribbon domain HC2 PF07382.6 AIO02047.1 - 2.9e-07 30.5 14.0 8.5e-05 22.5 6.7 2.1 1 1 1 2 2 2 2 Histone H1-like nucleoprotein HC2 LisH PF08513.6 AIO02047.1 - 0.068 12.9 0.4 0.099 12.4 0.3 1.2 1 0 0 1 1 1 0 LisH TPR_12 PF13424.1 AIO02048.1 - 0.0016 18.3 8.7 0.028 14.3 1.4 3.2 2 1 2 4 4 4 3 Tetratricopeptide repeat TPR_11 PF13414.1 AIO02048.1 - 0.17 11.5 3.7 1.5 8.4 1.5 2.8 1 1 2 3 3 3 0 TPR repeat TPR_10 PF13374.1 AIO02048.1 - 6.2 6.8 11.3 13 5.9 0.0 4.4 5 0 0 5 5 5 0 Tetratricopeptide repeat Snf7 PF03357.16 AIO02049.1 - 3.7e-18 65.4 22.9 3.7e-18 65.4 15.9 1.7 1 1 1 2 2 2 1 Snf7 KfrA_N PF11740.3 AIO02049.1 - 0.023 15.1 0.9 0.023 15.1 0.6 1.7 2 1 0 2 2 2 0 Plasmid replication region DNA-binding N-term Mating_C PF12737.2 AIO02049.1 - 0.03 13.2 1.6 0.052 12.4 1.1 1.4 1 1 0 1 1 1 0 C-terminal domain of homeodomain 1 DUF3385 PF11865.3 AIO02049.1 - 0.16 11.8 3.0 0.27 11.1 2.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3385) CCDC66 PF15236.1 AIO02049.1 - 0.29 10.7 13.5 0.21 11.2 1.1 2.2 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 66 AA_permease_2 PF13520.1 AIO02050.1 - 5.3e-36 124.0 49.7 6.9e-36 123.6 34.4 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 AIO02050.1 - 3.8e-09 35.4 40.3 6e-09 34.7 28.0 1.3 1 0 0 1 1 1 1 Amino acid permease Mito_carr PF00153.22 AIO02051.1 - 3.1e-33 113.3 9.2 1.3e-17 63.3 0.1 3.3 3 1 0 3 3 3 3 Mitochondrial carrier protein ArsB PF02040.10 AIO02051.1 - 0.0039 16.2 0.2 0.0067 15.4 0.1 1.3 1 0 0 1 1 1 1 Arsenical pump membrane protein zf-CCCH PF00642.19 AIO02053.1 - 0.17 11.5 2.6 0.38 10.4 1.8 1.5 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) LSM PF01423.17 AIO02054.1 - 1e-18 66.6 0.0 1.1e-18 66.4 0.0 1.0 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 AIO02054.1 - 4.7e-05 23.2 0.0 5.4e-05 23.0 0.0 1.1 1 0 0 1 1 1 1 Ataxin 2 SM domain LSM14 PF12701.2 AIO02054.1 - 0.069 12.9 0.0 0.079 12.7 0.0 1.2 1 0 0 1 1 1 0 Scd6-like Sm domain CS PF04969.11 AIO02055.1 - 3.5e-10 40.2 0.0 4.8e-10 39.8 0.0 1.2 1 0 0 1 1 1 1 CS domain ARL2_Bind_BART PF11527.3 AIO02056.1 - 8e-05 22.4 0.3 0.00015 21.4 0.2 1.6 1 1 0 1 1 1 1 The ARF-like 2 binding protein BART zf-Apc11 PF12861.2 AIO02057.1 - 5.2e-29 99.9 10.2 5.6e-29 99.8 7.1 1.0 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.2 AIO02057.1 - 3.1e-25 88.0 11.5 3.5e-25 87.9 8.0 1.0 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_2 PF13639.1 AIO02057.1 - 2e-07 30.7 21.5 1.1e-06 28.3 14.3 2.5 1 1 1 2 2 2 1 Ring finger domain zf-C3HC4_3 PF13920.1 AIO02057.1 - 8.3e-05 22.1 17.0 0.021 14.4 7.9 2.5 1 1 1 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 AIO02057.1 - 0.00022 20.7 17.1 0.00026 20.5 10.8 2.0 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 AIO02057.1 - 0.00043 20.2 16.3 0.005 16.8 10.6 2.3 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 AIO02057.1 - 0.00053 19.6 18.8 0.0078 15.9 12.1 2.3 1 1 1 2 2 2 2 zinc-RING finger domain zf-RING_4 PF14570.1 AIO02057.1 - 0.002 17.6 2.9 0.002 17.6 2.0 2.9 1 1 1 2 2 2 1 RING/Ubox like zinc-binding domain zf-C3HC4_4 PF15227.1 AIO02057.1 - 0.012 15.4 4.5 0.012 15.4 3.1 2.5 2 1 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-HIT PF04438.11 AIO02057.1 - 0.21 11.2 10.8 0.5 10.0 4.1 2.4 2 1 0 2 2 2 0 HIT zinc finger zf-Nse PF11789.3 AIO02057.1 - 0.73 9.3 10.4 1.1 8.8 7.2 1.3 1 1 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-RING-like PF08746.6 AIO02057.1 - 1.1 9.3 16.8 10 6.2 11.7 2.4 1 1 0 1 1 1 0 RING-like domain zf-HC5HC2H PF13771.1 AIO02057.1 - 3.1 8.0 11.0 17 5.6 7.6 2.1 1 1 0 1 1 1 0 PHD-like zinc-binding domain PHD PF00628.24 AIO02057.1 - 3.1 7.5 15.4 46 3.8 10.7 2.5 1 1 0 1 1 1 0 PHD-finger zf-HC5HC2H_2 PF13832.1 AIO02057.1 - 3.5 7.6 10.0 5.5 7.0 7.0 1.5 1 1 0 1 1 1 0 PHD-zinc-finger like domain DUF2833 PF11090.3 AIO02058.1 - 0.028 14.5 0.0 0.047 13.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2833) DUF962 PF06127.6 AIO02059.1 - 1.5e-21 76.0 1.9 3.1e-21 75.0 1.3 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF962) ABC_transp_aux PF09822.4 AIO02060.1 - 0.11 11.9 0.0 0.26 10.6 0.0 1.6 1 0 0 1 1 1 0 ABC-type uncharacterized transport system FPL PF09758.4 AIO02061.1 - 5.6e-56 188.4 1.8 1e-55 187.5 1.3 1.5 1 0 0 1 1 1 1 Uncharacterised conserved protein SET PF00856.23 AIO02062.1 - 2.9e-24 86.2 12.1 0.00074 19.8 0.0 9.4 11 0 0 11 11 11 5 SET domain SAF PF08666.7 AIO02062.1 - 5.9e-06 26.5 0.0 1.7e+02 2.6 0.0 9.5 13 0 0 13 13 13 0 SAF domain 60KD_IMP PF02096.15 AIO02065.1 - 8.3e-14 51.7 0.0 1.2e-13 51.1 0.0 1.2 1 0 0 1 1 1 1 60Kd inner membrane protein PS_Dcarbxylase PF02666.10 AIO02066.1 - 5.3e-39 133.6 0.0 6.8e-39 133.2 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase Meth_synt_2 PF01717.13 AIO02067.1 - 0.021 13.8 0.2 0.041 12.8 0.1 1.5 1 0 0 1 1 1 0 Cobalamin-independent synthase, Catalytic domain Bap31 PF05529.7 AIO02067.1 - 0.45 9.9 9.1 22 4.4 3.8 3.5 3 1 0 3 3 3 0 B-cell receptor-associated protein 31-like DUF310 PF03750.8 AIO02067.1 - 0.72 10.0 4.1 22 5.2 0.2 3.2 2 1 0 3 3 3 0 Protein of unknown function (DUF310) TPR_MLP1_2 PF07926.7 AIO02067.1 - 1.7 8.3 36.5 0.15 11.8 0.7 5.1 4 1 0 4 4 4 0 TPR/MLP1/MLP2-like protein Pkinase PF00069.20 AIO02069.1 - 3.5e-09 36.2 0.0 7.7e-07 28.5 0.0 2.7 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 AIO02069.1 - 0.00012 21.2 0.0 0.00025 20.2 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase DnaJ PF00226.26 AIO02070.1 - 1.3e-15 56.8 0.3 2.8e-15 55.8 0.2 1.5 1 0 0 1 1 1 1 DnaJ domain Atg14 PF10186.4 AIO02071.1 - 0.0002 20.4 16.5 0.00022 20.3 11.4 1.1 1 0 0 1 1 1 1 UV radiation resistance protein and autophagy-related subunit 14 EcoRII-C PF09019.6 AIO02071.1 - 0.025 14.4 1.9 0.034 13.9 1.3 1.4 1 1 0 1 1 1 0 EcoRII C terminal Med29 PF11568.3 AIO02071.1 - 0.044 13.8 4.6 0.062 13.3 3.0 1.4 1 1 0 1 1 1 0 Mediator complex subunit 29 AKNA PF12443.3 AIO02071.1 - 0.057 13.4 4.5 0.27 11.2 2.3 2.1 1 1 1 2 2 2 0 AT-hook-containing transcription factor Baculo_LEF-11 PF06385.7 AIO02071.1 - 0.079 13.0 6.9 1.1 9.3 0.4 2.1 1 1 1 2 2 2 0 Baculovirus LEF-11 protein FAM178 PF14816.1 AIO02071.1 - 0.24 10.0 2.8 0.27 9.8 2.0 1.1 1 0 0 1 1 1 0 Family of unknown function, FAM178 Cgr1 PF03879.9 AIO02071.1 - 0.32 11.1 21.3 0.42 10.8 14.8 1.3 1 0 0 1 1 1 0 Cgr1 family Stn1 PF10451.4 AIO02071.1 - 0.34 9.6 2.8 0.38 9.5 1.9 1.1 1 0 0 1 1 1 0 Telomere regulation protein Stn1 CENP-K PF11802.3 AIO02071.1 - 0.42 9.8 8.0 0.53 9.4 5.6 1.1 1 0 0 1 1 1 0 Centromere-associated protein K Casc1 PF12366.3 AIO02071.1 - 0.62 9.5 7.1 0.74 9.2 4.9 1.1 1 0 0 1 1 1 0 Cancer susceptibility candidate 1 Vfa1 PF08432.5 AIO02071.1 - 0.91 9.5 10.3 1.2 9.1 7.1 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 L31 PF09784.4 AIO02071.1 - 1.4 9.0 8.6 2.1 8.4 6.0 1.4 1 0 0 1 1 1 0 Mitochondrial ribosomal protein L31 D5_N PF08706.6 AIO02071.1 - 2.3 8.2 6.5 2.8 8.0 4.5 1.1 1 0 0 1 1 1 0 D5 N terminal like DUF2756 PF10956.3 AIO02071.1 - 5.3 7.3 10.9 6.3 7.1 7.2 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2756) DSPc PF00782.15 AIO02072.1 - 6.9e-20 70.9 0.0 1.1e-19 70.3 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 AIO02072.1 - 0.0013 18.1 0.0 0.0019 17.5 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.1 AIO02072.1 - 0.062 13.5 0.1 0.47 10.6 0.0 2.0 1 1 1 2 2 2 0 Tyrosine phosphatase family zf-SNAP50_C PF12251.3 AIO02073.1 - 4.6e-54 182.7 0.2 6.4e-54 182.3 0.1 1.2 1 0 0 1 1 1 1 snRNA-activating protein of 50kDa MW C terminal Katanin_con80 PF13925.1 AIO02074.1 - 7.6e-42 142.8 0.0 1e-41 142.4 0.0 1.2 1 0 0 1 1 1 1 con80 domain of Katanin WD40 PF00400.27 AIO02074.1 - 2.1e-29 100.2 7.8 7.9e-10 38.2 0.1 5.7 6 0 0 6 6 6 4 WD domain, G-beta repeat Nup160 PF11715.3 AIO02074.1 - 0.045 11.8 1.2 0.23 9.5 0.1 2.3 1 1 2 3 3 3 0 Nucleoporin Nup120/160 ParcG PF10274.4 AIO02075.1 - 4e-74 248.4 0.0 5e-74 248.1 0.0 1.1 1 0 0 1 1 1 1 Parkin co-regulated protein Kinesin PF00225.18 AIO02076.1 - 1.3e-57 195.0 0.4 2.9e-57 193.8 0.3 1.5 1 1 0 1 1 1 1 Kinesin motor domain AAA_16 PF13191.1 AIO02076.1 - 0.00051 20.0 0.1 0.0014 18.6 0.0 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 AIO02076.1 - 0.049 13.7 0.0 0.12 12.4 0.0 1.8 1 0 0 1 1 1 0 AAA domain DUF87 PF01935.12 AIO02076.1 - 0.053 13.3 0.1 0.25 11.1 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function DUF87 HSP70 PF00012.15 AIO02077.1 - 2.6e-61 207.2 0.0 5.1e-61 206.3 0.0 1.5 1 1 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 AIO02077.1 - 0.0039 15.8 0.0 0.019 13.5 0.0 2.1 2 0 0 2 2 2 1 MreB/Mbl protein GCV_H PF01597.14 AIO02078.1 - 1.4e-40 137.7 1.1 1.6e-40 137.5 0.8 1.0 1 0 0 1 1 1 1 Glycine cleavage H-protein Biotin_lipoyl PF00364.17 AIO02078.1 - 4.8e-07 29.3 0.4 8.8e-07 28.4 0.3 1.4 1 0 0 1 1 1 1 Biotin-requiring enzyme RnfC_N PF13375.1 AIO02078.1 - 0.00015 21.3 0.3 0.00023 20.8 0.2 1.2 1 0 0 1 1 1 1 RnfC Barrel sandwich hybrid domain PTS_EIIA_1 PF00358.15 AIO02078.1 - 0.0032 17.0 0.1 0.0041 16.6 0.0 1.3 1 0 0 1 1 1 1 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 MS_channel PF00924.13 AIO02078.1 - 0.089 12.1 0.0 0.13 11.6 0.0 1.2 1 0 0 1 1 1 0 Mechanosensitive ion channel Peptidase_M23 PF01551.17 AIO02078.1 - 0.13 12.3 1.0 11 6.1 0.1 2.3 1 1 1 2 2 2 0 Peptidase family M23 Gp_dh_N PF00044.19 AIO02079.1 - 1.9e-20 73.3 0.0 3.7e-20 72.4 0.0 1.4 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain Gp_dh_C PF02800.15 AIO02079.1 - 6.2e-13 48.4 0.1 1.1e-12 47.7 0.1 1.4 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain DUF1943 PF09172.6 AIO02079.1 - 0.18 10.6 0.0 0.27 10.0 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1943) Spore_YabQ PF09578.5 AIO02080.1 - 0.027 14.4 0.2 0.057 13.3 0.2 1.6 1 0 0 1 1 1 0 Spore cortex protein YabQ (Spore_YabQ) DUF1761 PF08570.5 AIO02080.1 - 0.36 10.8 4.2 0.88 9.5 2.9 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1761) Pro_isomerase PF00160.16 AIO02081.1 - 2.2e-44 151.3 0.7 3.7e-44 150.6 0.5 1.4 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD TPR_11 PF13414.1 AIO02081.1 - 5.7e-15 54.7 6.6 7.8e-09 35.0 0.5 2.2 2 0 0 2 2 2 2 TPR repeat TPR_2 PF07719.12 AIO02081.1 - 3.6e-07 29.6 0.2 0.058 13.3 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.23 AIO02081.1 - 3.2e-06 26.5 0.1 0.072 12.7 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat Apc3 PF12895.2 AIO02081.1 - 0.00081 19.4 3.4 0.034 14.2 0.3 2.4 1 1 1 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.1 AIO02081.1 - 0.0011 19.2 0.3 3 8.5 0.0 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.1 AIO02081.1 - 0.0014 18.5 1.0 0.093 12.6 0.1 2.4 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.1 AIO02081.1 - 0.0027 18.0 2.7 2.5 8.4 0.1 3.0 1 1 1 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.1 AIO02081.1 - 0.005 17.4 1.3 0.024 15.3 0.4 2.2 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_9 PF13371.1 AIO02081.1 - 0.013 15.3 1.0 0.024 14.4 0.4 1.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.1 AIO02081.1 - 0.014 15.9 1.2 0.23 12.2 0.2 2.9 2 1 1 3 3 3 0 Tetratricopeptide repeat Coatomer_E PF04733.9 AIO02081.1 - 0.019 14.1 1.4 0.025 13.7 0.5 1.5 1 1 0 1 1 1 0 Coatomer epsilon subunit TPR_8 PF13181.1 AIO02081.1 - 0.079 12.7 0.5 8.6 6.3 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF1418 PF07214.7 AIO02082.1 - 0.026 14.1 0.3 0.032 13.8 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1418) SCAMP PF04144.8 AIO02083.1 - 2.4e-49 167.6 12.5 3e-49 167.3 8.6 1.0 1 0 0 1 1 1 1 SCAMP family DUF1129 PF06570.6 AIO02083.1 - 0.18 11.1 9.7 0.31 10.3 6.7 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1129) DUF1212 PF06738.7 AIO02083.1 - 0.59 9.5 12.5 0.72 9.2 1.6 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1212) A_deaminase PF00962.17 AIO02084.1 - 2.1e-103 345.7 0.0 5.8e-79 265.4 0.0 2.3 2 0 0 2 2 2 2 Adenosine/AMP deaminase BRCT PF00533.21 AIO02085.1 - 8.7e-08 32.2 0.0 0.0024 17.9 0.0 2.5 2 0 0 2 2 2 2 BRCA1 C Terminus (BRCT) domain zf-C3HC4_3 PF13920.1 AIO02085.1 - 0.036 13.7 4.7 0.82 9.3 0.2 2.5 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Cript PF10235.4 AIO02085.1 - 0.15 12.4 2.8 0.19 12.1 0.6 2.1 2 0 0 2 2 2 0 Microtubule-associated protein CRIPT His_Phos_1 PF00300.17 AIO02086.1 - 5.5e-12 46.0 0.0 2.3e-11 44.0 0.0 1.9 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) UBA PF00627.26 AIO02087.1 - 0.00072 19.3 0.0 0.0015 18.3 0.0 1.6 1 0 0 1 1 1 1 UBA/TS-N domain Rap1_C PF11626.3 AIO02087.1 - 0.084 12.7 0.2 0.68 9.8 0.1 2.5 1 1 0 1 1 1 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain Radical_SAM PF04055.16 AIO02087.1 - 0.14 12.3 0.0 0.36 10.9 0.0 1.8 1 1 0 1 1 1 0 Radical SAM superfamily Nitrate_red_del PF02613.10 AIO02088.1 - 0.054 13.3 0.1 0.16 11.7 0.0 1.6 1 1 0 1 1 1 0 Nitrate reductase delta subunit Proteasome PF00227.21 AIO02089.1 - 1.5e-37 128.7 0.0 2.1e-37 128.2 0.0 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 AIO02089.1 - 1.3e-11 43.5 0.2 1.3e-11 43.5 0.1 1.8 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature Porin_3 PF01459.17 AIO02090.1 - 0.099 11.9 2.5 0.14 11.4 1.7 1.3 1 0 0 1 1 1 0 Eukaryotic porin TPR_11 PF13414.1 AIO02092.1 - 5e-16 58.0 9.5 1.2e-15 56.9 4.4 2.6 2 1 1 3 3 2 2 TPR repeat TPR_1 PF00515.23 AIO02092.1 - 1e-12 47.0 8.8 2e-05 23.9 0.1 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.12 AIO02092.1 - 5.5e-09 35.2 17.4 0.00041 20.0 0.1 4.1 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.1 AIO02092.1 - 8.1e-06 25.6 6.1 0.00019 21.3 2.1 2.4 1 1 1 2 2 2 1 Tetratricopeptide repeat UPF0121 PF03661.8 AIO02092.1 - 1.1e-05 24.7 8.9 1.7e-05 24.1 6.2 1.3 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0121) TPR_17 PF13431.1 AIO02092.1 - 1.8e-05 24.5 2.4 4e-05 23.4 0.9 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.1 AIO02092.1 - 0.0012 19.4 1.8 0.0012 19.4 1.2 2.8 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.1 AIO02092.1 - 0.003 17.2 8.3 0.03 14.1 2.0 3.1 2 1 1 3 3 3 1 Tetratricopeptide repeat Apc3 PF12895.2 AIO02092.1 - 0.0067 16.5 3.2 0.014 15.4 2.2 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.1 AIO02092.1 - 0.0086 16.6 5.5 3.3 8.6 0.0 3.8 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.1 AIO02092.1 - 0.023 14.4 1.2 1.2 9.1 0.2 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_19 PF14559.1 AIO02092.1 - 0.025 14.9 1.1 0.025 14.9 0.8 2.4 2 1 1 3 3 2 0 Tetratricopeptide repeat Rad51 PF08423.6 AIO02093.1 - 1.2e-133 443.8 0.0 1.6e-133 443.3 0.0 1.2 1 0 0 1 1 1 1 Rad51 RecA PF00154.16 AIO02093.1 - 1.1e-11 44.4 0.3 1.4e-11 44.0 0.2 1.1 1 0 0 1 1 1 1 recA bacterial DNA recombination protein AAA_25 PF13481.1 AIO02093.1 - 6.1e-10 38.8 0.0 1e-09 38.0 0.0 1.3 1 0 0 1 1 1 1 AAA domain HHH_5 PF14520.1 AIO02093.1 - 7e-08 32.5 0.3 1.5e-07 31.4 0.2 1.5 1 0 0 1 1 1 1 Helix-hairpin-helix domain KaiC PF06745.8 AIO02093.1 - 9.8e-08 31.3 0.0 1.7e-07 30.5 0.0 1.4 1 1 0 1 1 1 1 KaiC AAA_24 PF13479.1 AIO02093.1 - 0.14 11.6 0.0 0.34 10.4 0.0 1.5 1 1 0 1 1 1 0 AAA domain MCM PF00493.18 AIO02095.1 - 1.3e-81 274.0 0.0 1.9e-81 273.4 0.0 1.2 1 0 0 1 1 1 1 MCM2/3/5 family AAA_5 PF07728.9 AIO02095.1 - 0.00021 20.9 0.0 0.0012 18.6 0.0 2.1 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.16 AIO02095.1 - 0.00048 19.3 0.0 0.03 13.4 0.0 2.5 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.6 AIO02095.1 - 0.023 14.3 0.0 0.063 12.8 0.0 1.8 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) TTL PF03133.10 AIO02096.1 - 2.1e-74 250.1 0.0 3.3e-74 249.4 0.0 1.2 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.1 AIO02096.1 - 0.002 17.0 0.1 0.0059 15.4 0.0 1.8 2 0 0 2 2 2 1 YheC/D like ATP-grasp DUF3316 PF11777.3 AIO02097.1 - 0.12 12.1 0.3 0.2 11.4 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3316) DUF241 PF03087.9 AIO02097.1 - 0.15 11.5 2.8 1.1 8.7 1.3 1.9 1 1 0 1 1 1 0 Arabidopsis protein of unknown function zf-CCCH PF00642.19 AIO02098.1 - 0.0037 16.9 4.2 0.0068 16.0 2.9 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) PAP2_C PF14360.1 AIO02101.1 - 6e-20 71.2 8.7 6e-20 71.2 6.0 2.0 2 0 0 2 2 2 1 PAP2 superfamily C-terminal PAP2_3 PF14378.1 AIO02101.1 - 0.048 13.1 7.6 0.088 12.3 5.2 1.6 1 1 0 1 1 1 0 PAP2 superfamily PAP2 PF01569.16 AIO02101.1 - 0.97 9.1 11.3 0.1 12.2 4.3 2.0 2 1 0 2 2 2 0 PAP2 superfamily PSP1 PF04468.7 AIO02102.1 - 2.3e-15 56.3 0.7 3.4e-15 55.7 0.5 1.2 1 0 0 1 1 1 1 PSP1 C-terminal conserved region Pkinase PF00069.20 AIO02103.1 - 6.8e-68 228.6 0.0 8.4e-68 228.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AIO02103.1 - 3.5e-30 104.9 0.0 1.5e-29 102.9 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 AIO02103.1 - 2.6e-05 23.3 0.0 0.00013 21.0 0.0 1.9 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 AIO02103.1 - 0.016 14.9 0.0 0.026 14.2 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 AIO02103.1 - 0.025 13.4 0.0 0.046 12.5 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 RRM_1 PF00076.17 AIO02106.1 - 8.9e-78 255.9 4.3 6.4e-21 73.7 0.0 4.2 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 AIO02106.1 - 1.1e-50 169.5 3.5 8e-16 57.7 0.0 4.3 4 0 0 4 4 4 4 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 AIO02106.1 - 4.4e-35 119.3 1.9 5.3e-10 38.9 0.0 4.4 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP PF00658.13 AIO02106.1 - 2.3e-21 75.2 0.2 1.2e-19 69.7 0.0 2.5 2 0 0 2 2 2 1 Poly-adenylate binding protein, unique domain RRM_3 PF08777.6 AIO02106.1 - 8.3e-05 22.3 0.8 0.94 9.3 0.2 4.2 4 0 0 4 4 4 1 RNA binding motif Nup35_RRM_2 PF14605.1 AIO02106.1 - 0.0022 17.6 0.4 4.1 7.2 0.0 4.1 4 0 0 4 4 4 1 Nup53/35/40-type RNA recognition motif DUF4523 PF15023.1 AIO02106.1 - 0.025 14.0 0.0 5.9 6.3 0.0 3.1 2 1 0 3 3 3 0 Protein of unknown function (DUF4523) PAT1 PF09770.4 AIO02106.1 - 5.6 5.0 12.8 7.8 4.5 8.9 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 UCR_hinge PF02320.11 AIO02108.1 - 0.22 11.4 2.5 4 7.4 0.2 3.2 3 0 0 3 3 3 0 Ubiquinol-cytochrome C reductase hinge protein TF_Zn_Ribbon PF08271.7 AIO02109.1 - 0.1 11.9 0.5 0.3 10.4 0.3 1.8 1 0 0 1 1 1 0 TFIIB zinc-binding DUF1664 PF07889.7 AIO02110.1 - 0.0014 18.4 0.2 0.0028 17.4 0.1 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF1664) MAT1 PF06391.8 AIO02110.1 - 0.031 13.8 1.1 0.054 13.0 0.7 1.4 1 1 0 1 1 1 0 CDK-activating kinase assembly factor MAT1 CENP-Q PF13094.1 AIO02110.1 - 0.17 11.9 3.0 0.25 11.3 2.1 1.2 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit Occludin_ELL PF07303.8 AIO02110.1 - 0.27 11.9 2.3 0.69 10.6 1.6 1.7 1 1 0 1 1 1 0 Occludin homology domain NPV_P10 PF05531.7 AIO02110.1 - 0.3 11.3 1.6 3.8 7.8 1.2 2.6 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein RNase_Zc3h12a PF11977.3 AIO02111.1 - 0.036 13.8 0.1 0.44 10.3 0.0 2.3 2 0 0 2 2 2 0 Zc3h12a-like Ribonuclease NYN domain Ribosomal_L37e PF01907.14 AIO02112.1 - 3.4e-22 77.9 7.7 6e-22 77.1 5.3 1.4 1 0 0 1 1 1 1 Ribosomal protein L37e DZR PF12773.2 AIO02112.1 - 0.067 13.0 0.8 0.11 12.3 0.5 1.4 1 0 0 1 1 1 0 Double zinc ribbon zinc_ribbon_6 PF14599.1 AIO02112.1 - 0.11 12.3 0.6 0.17 11.7 0.4 1.3 1 0 0 1 1 1 0 Zinc-ribbon ATE_N PF04376.8 AIO02112.1 - 0.64 9.8 5.7 0.72 9.6 2.7 1.8 1 1 1 2 2 2 0 Arginine-tRNA-protein transferase, N terminus PseudoU_synth_2 PF00849.17 AIO02113.1 - 4.5e-25 88.3 0.1 7.5e-25 87.6 0.1 1.4 1 0 0 1 1 1 1 RNA pseudouridylate synthase ALF PF03752.8 AIO02113.1 - 0.0022 17.7 2.0 0.0022 17.7 1.4 2.0 2 0 0 2 2 2 1 Short repeats of unknown function Methyltransf_11 PF08241.7 AIO02117.1 - 1.3e-05 25.5 0.0 0.001 19.4 0.0 2.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 AIO02117.1 - 0.00033 20.4 0.0 0.00052 19.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 AIO02117.1 - 0.00091 19.7 0.0 0.0025 18.3 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 AIO02117.1 - 0.0014 18.2 0.0 0.11 12.1 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 AIO02117.1 - 0.0045 17.4 0.0 0.0099 16.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain BT1 PF03092.11 AIO02118.1 - 5.3e-154 513.0 11.9 6.8e-154 512.7 8.2 1.0 1 0 0 1 1 1 1 BT1 family DUF4231 PF14015.1 AIO02118.1 - 0.11 12.4 0.0 0.11 12.4 0.0 3.0 4 1 0 4 4 4 0 Protein of unknown function (DUF4231) Zeta_toxin PF06414.7 AIO02119.1 - 3.1e-06 26.4 0.0 4.3e-06 25.9 0.0 1.2 1 0 0 1 1 1 1 Zeta toxin AAA_28 PF13521.1 AIO02119.1 - 2.1e-05 24.5 0.0 3.5e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 AIO02119.1 - 8e-05 22.6 0.1 0.00012 22.1 0.0 1.2 1 0 0 1 1 1 1 AAA ATPase domain AAA_33 PF13671.1 AIO02119.1 - 0.00019 21.3 0.0 0.00071 19.4 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 AIO02119.1 - 0.00025 21.8 0.0 0.00043 21.1 0.0 1.7 1 1 0 1 1 1 1 AAA domain Arch_ATPase PF01637.13 AIO02119.1 - 0.0011 18.6 0.0 0.0017 18.1 0.0 1.3 1 0 0 1 1 1 1 Archaeal ATPase AAA_14 PF13173.1 AIO02119.1 - 0.003 17.4 0.0 0.0056 16.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 AIO02119.1 - 0.0057 16.9 0.0 0.011 16.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 AIO02119.1 - 0.012 15.7 0.0 0.022 14.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 AIO02119.1 - 0.04 14.1 0.0 0.078 13.1 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_5 PF07728.9 AIO02119.1 - 0.049 13.3 0.0 0.43 10.3 0.0 2.3 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA PF00004.24 AIO02119.1 - 0.084 13.0 0.0 0.29 11.3 0.0 2.0 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) KTI12 PF08433.5 AIO02119.1 - 0.1 11.7 0.0 0.17 11.0 0.0 1.3 1 0 0 1 1 1 0 Chromatin associated protein KTI12 Rad17 PF03215.10 AIO02119.1 - 0.16 10.6 0.0 0.2 10.2 0.0 1.1 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein MMR_HSR1 PF01926.18 AIO02120.1 - 0.00034 20.5 0.0 0.00056 19.8 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.1 AIO02120.1 - 0.055 13.4 0.0 0.21 11.5 0.0 1.8 2 0 0 2 2 2 0 AAA ATPase domain FtsK_SpoIIIE PF01580.13 AIO02120.1 - 0.075 12.4 0.0 0.15 11.5 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family DUF3948 PF13134.1 AIO02120.1 - 0.12 11.8 0.0 0.27 10.7 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3948) Pkinase PF00069.20 AIO02122.1 - 4.2e-53 180.1 0.0 6.1e-53 179.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AIO02122.1 - 1.2e-34 119.5 0.0 1.8e-34 118.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 AIO02122.1 - 4.8e-08 32.3 0.0 1.2e-07 31.0 0.0 1.5 1 1 1 2 2 2 1 Kinase-like PH PF00169.24 AIO02122.1 - 1.7e-06 28.2 0.0 3.2e-06 27.2 0.0 1.5 1 0 0 1 1 1 1 PH domain Mcp5_PH PF12814.2 AIO02122.1 - 0.00027 20.8 0.0 0.00049 20.0 0.0 1.3 1 0 0 1 1 1 1 Meiotic cell cortex C-terminal pleckstrin homology BORA_N PF15280.1 AIO02123.1 - 0.0011 18.4 0.7 0.0011 18.4 0.5 1.5 2 0 0 2 2 2 1 Protein aurora borealis N-terminus zf-CCCH PF00642.19 AIO02123.1 - 0.0088 15.6 6.4 0.01 15.5 0.1 2.4 2 0 0 2 2 2 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) MMR_HSR1 PF01926.18 AIO02124.1 - 1.5e-12 47.4 0.0 1.6e-10 40.9 0.0 2.3 2 0 0 2 2 2 1 50S ribosome-binding GTPase DUF258 PF03193.11 AIO02124.1 - 6.6e-05 22.1 0.0 0.00014 21.1 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_22 PF13401.1 AIO02124.1 - 0.0083 16.2 0.0 0.02 15.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain Dynamin_N PF00350.18 AIO02124.1 - 0.0088 15.8 0.5 2.6 7.8 0.0 2.8 2 1 1 3 3 3 2 Dynamin family FeoB_N PF02421.13 AIO02124.1 - 0.025 13.8 0.0 0.052 12.8 0.0 1.5 1 0 0 1 1 1 0 Ferrous iron transport protein B Septin PF00735.13 AIO02124.1 - 0.09 11.7 0.0 0.21 10.5 0.0 1.5 2 0 0 2 2 2 0 Septin RRN3 PF05327.6 AIO02125.1 - 0.04 12.0 2.0 0.048 11.7 0.0 2.0 3 0 0 3 3 3 0 RNA polymerase I specific transcription initiation factor RRN3 bZIP_2 PF07716.10 AIO02125.1 - 0.46 10.3 6.5 9.9 6.0 0.1 2.9 2 0 0 2 2 2 0 Basic region leucine zipper Shugoshin_N PF07558.6 AIO02125.1 - 0.84 9.4 7.6 1.6 8.4 0.6 2.7 3 0 0 3 3 3 0 Shugoshin N-terminal coiled-coil region DUF972 PF06156.8 AIO02125.1 - 6.4 7.1 8.4 5 7.5 0.6 3.7 3 2 2 5 5 5 0 Protein of unknown function (DUF972) DUF4201 PF13870.1 AIO02125.1 - 9.8 5.5 13.7 0.37 10.2 3.0 3.1 3 1 1 4 4 4 0 Domain of unknown function (DUF4201) Methyltransf_4 PF02390.12 AIO02126.1 - 2.5e-37 127.8 0.0 3.1e-37 127.5 0.0 1.1 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_18 PF12847.2 AIO02126.1 - 0.00018 22.0 0.0 0.0004 20.9 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 AIO02126.1 - 0.00044 19.8 0.0 0.0017 17.9 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 AIO02126.1 - 0.022 15.2 0.0 0.046 14.1 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Glycos_transf_1 PF00534.15 AIO02127.1 - 2.4e-20 72.6 0.0 3.5e-20 72.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 AIO02127.1 - 1.3e-08 35.0 0.0 2.6e-08 34.1 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.1 AIO02127.1 - 0.0041 17.3 0.0 0.013 15.7 0.0 1.9 1 0 0 1 1 1 1 Glycosyl transferases group 1 HALZ PF02183.13 AIO02128.1 - 2.6e-05 23.8 0.7 2.6e-05 23.8 0.5 1.7 2 0 0 2 2 2 1 Homeobox associated leucine zipper Kinesin-relat_1 PF12711.2 AIO02128.1 - 0.011 16.0 0.6 0.03 14.7 0.0 1.8 1 1 1 2 2 2 0 Kinesin motor DivIVA PF05103.8 AIO02128.1 - 0.013 15.5 0.6 0.013 15.5 0.4 1.7 1 1 1 2 2 2 0 DivIVA protein DivIC PF04977.10 AIO02128.1 - 0.017 14.6 0.5 0.017 14.6 0.4 1.8 2 0 0 2 2 2 0 Septum formation initiator bZIP_1 PF00170.16 AIO02128.1 - 0.034 14.0 0.1 0.034 14.0 0.1 1.8 2 1 0 2 2 2 0 bZIP transcription factor Dpy-30 PF05186.8 AIO02128.1 - 0.035 13.5 0.2 0.089 12.2 0.1 1.7 1 1 0 1 1 1 0 Dpy-30 motif Urb2 PF10441.4 AIO02128.1 - 0.087 12.4 0.1 0.087 12.4 0.0 1.1 1 0 0 1 1 1 0 Urb2/Npa2 family K-box PF01486.12 AIO02128.1 - 0.12 12.2 0.9 0.18 11.6 0.1 1.7 2 0 0 2 2 2 0 K-box region SinI PF08671.5 AIO02128.1 - 0.13 11.7 0.4 0.22 10.9 0.3 1.4 1 0 0 1 1 1 0 Anti-repressor SinI Kinetocho_Slk19 PF12709.2 AIO02128.1 - 0.13 12.3 2.4 0.16 12.1 1.7 1.2 1 0 0 1 1 1 0 Central kinetochore-associated FlaC_arch PF05377.6 AIO02128.1 - 0.14 12.0 0.6 1.3 8.9 0.0 2.1 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) bZIP_2 PF07716.10 AIO02128.1 - 0.97 9.3 5.3 0.21 11.4 1.1 1.7 2 0 0 2 2 2 0 Basic region leucine zipper WD40 PF00400.27 AIO02129.1 - 7.4e-17 60.5 10.5 2.2e-06 27.3 0.0 4.4 4 0 0 4 4 4 3 WD domain, G-beta repeat AD PF09793.4 AIO02131.1 - 0.0033 17.2 0.0 0.0054 16.5 0.0 1.3 1 0 0 1 1 1 1 Anticodon-binding domain 7tm_6 PF02949.15 AIO02132.1 - 0.057 12.2 1.0 0.098 11.4 0.7 1.3 1 0 0 1 1 1 0 7tm Odorant receptor Phage_fiber PF03335.8 AIO02132.1 - 1.1 9.2 5.9 1.2 9.0 0.5 2.9 2 0 0 2 2 2 0 Phage tail fibre repeat TGS PF02824.16 AIO02133.1 - 1.2e-21 76.2 0.1 2.4e-21 75.3 0.0 1.5 1 0 0 1 1 1 1 TGS domain MMR_HSR1 PF01926.18 AIO02133.1 - 3.1e-16 59.3 0.0 6.8e-16 58.2 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 AIO02133.1 - 4.5e-11 42.2 0.0 7.4e-11 41.5 0.0 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B Miro PF08477.8 AIO02133.1 - 0.0005 20.5 0.0 0.0018 18.7 0.0 2.0 2 0 0 2 2 2 1 Miro-like protein Dynamin_N PF00350.18 AIO02133.1 - 0.0018 18.1 0.3 0.49 10.1 0.0 2.4 1 1 1 2 2 2 2 Dynamin family AIG1 PF04548.11 AIO02133.1 - 0.075 12.1 0.0 0.12 11.4 0.0 1.3 1 0 0 1 1 1 0 AIG1 family SAC3_GANP PF03399.11 AIO02134.1 - 4.6e-29 101.4 0.4 6.8e-29 100.8 0.3 1.3 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family FMN_dh PF01070.13 AIO02135.1 - 1.1e-32 113.2 0.0 1.1e-21 77.0 0.0 2.0 1 1 1 2 2 2 2 FMN-dependent dehydrogenase IMPDH PF00478.20 AIO02135.1 - 1e-06 27.9 0.9 0.0033 16.3 0.2 2.2 1 1 1 2 2 2 2 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.12 AIO02135.1 - 0.00035 19.5 0.9 0.002 17.0 0.7 1.9 1 1 0 1 1 1 1 Conserved region in glutamate synthase NMO PF03060.10 AIO02135.1 - 0.031 13.4 0.1 0.05 12.7 0.1 1.3 1 0 0 1 1 1 0 Nitronate monooxygenase DHO_dh PF01180.16 AIO02135.1 - 0.036 13.0 0.0 0.063 12.2 0.0 1.4 1 0 0 1 1 1 0 Dihydroorotate dehydrogenase His_biosynth PF00977.16 AIO02135.1 - 0.34 10.1 1.5 1.3 8.2 0.1 2.2 2 1 1 3 3 3 0 Histidine biosynthesis protein Ank_2 PF12796.2 AIO02136.1 - 9.7e-07 29.0 0.0 2e-06 28.0 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Dynein_heavy PF03028.10 AIO02136.1 - 1.7e-06 26.4 0.0 2.2e-06 26.0 0.0 1.1 1 0 0 1 1 1 1 Dynein heavy chain and region D6 of dynein motor Ank PF00023.25 AIO02136.1 - 4.4e-06 26.2 0.0 0.00042 19.9 0.0 2.8 2 1 0 2 2 2 1 Ankyrin repeat Ank_4 PF13637.1 AIO02136.1 - 2.8e-05 24.5 0.0 0.14 12.7 0.0 3.2 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 AIO02136.1 - 0.00049 20.0 0.0 0.34 11.2 0.0 3.1 2 0 0 2 2 2 2 Ankyrin repeat Aa_trans PF01490.13 AIO02137.1 - 2.2e-51 174.6 32.6 2.5e-51 174.4 22.6 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Aa_trans PF01490.13 AIO02138.1 - 5.6e-50 170.0 38.1 7.4e-50 169.6 26.4 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein DAGK_acc PF00609.14 AIO02139.1 - 2.6e-40 138.2 0.0 3.6e-40 137.7 0.0 1.2 1 0 0 1 1 1 1 Diacylglycerol kinase accessory domain DAGK_cat PF00781.19 AIO02139.1 - 4.2e-14 52.0 0.0 6.6e-14 51.4 0.0 1.3 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain NAD_kinase PF01513.16 AIO02139.1 - 0.0038 16.0 0.0 0.0057 15.4 0.0 1.2 1 0 0 1 1 1 1 ATP-NAD kinase Vps16_N PF04841.8 AIO02139.1 - 0.11 10.9 0.0 0.17 10.3 0.0 1.2 1 0 0 1 1 1 0 Vps16, N-terminal region HECT PF00632.20 AIO02141.1 - 2e-41 142.1 0.3 4.2e-41 141.1 0.2 1.4 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) SPRY PF00622.23 AIO02141.1 - 1.1e-10 41.7 0.5 3.1e-05 24.0 0.0 4.7 4 0 0 4 4 4 3 SPRY domain PdxA PF04166.7 AIO02141.1 - 4.1 6.5 0.2 7.5 5.6 0.2 1.3 1 0 0 1 1 1 0 Pyridoxal phosphate biosynthetic protein PdxA Histone PF00125.19 AIO02142.1 - 6.6e-13 48.5 0.5 8e-13 48.3 0.4 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 AIO02142.1 - 0.00049 20.0 0.5 0.00065 19.7 0.0 1.4 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TAF PF02969.12 AIO02142.1 - 0.001 18.9 0.1 0.0017 18.2 0.1 1.4 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) Bromo_TP PF07524.8 AIO02142.1 - 0.0037 16.9 0.0 0.0048 16.6 0.0 1.2 1 0 0 1 1 1 1 Bromodomain associated TFIID-31kDa PF02291.10 AIO02142.1 - 0.0046 16.7 0.0 0.0046 16.7 0.0 1.2 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit Amidohydro_4 PF13147.1 AIO02144.1 - 3.9e-21 76.3 0.0 8.1e-21 75.2 0.0 1.5 1 1 0 1 1 1 1 Amidohydrolase Amidohydro_1 PF01979.15 AIO02144.1 - 7.8e-07 29.0 1.6 0.0014 18.4 0.0 2.3 2 1 0 2 2 2 2 Amidohydrolase family Amidohydro_3 PF07969.6 AIO02144.1 - 7.3e-05 22.1 0.5 0.067 12.3 0.1 2.5 3 0 0 3 3 3 2 Amidohydrolase family Amidohydro_5 PF13594.1 AIO02144.1 - 0.00043 20.0 0.0 0.0011 18.6 0.0 1.8 1 0 0 1 1 1 1 Amidohydrolase PUF PF00806.14 AIO02145.1 - 1e-31 106.6 12.9 6.3e-06 25.3 0.1 7.6 7 0 0 7 7 7 7 Pumilio-family RNA binding repeat NatB_MDM20 PF09797.4 AIO02145.1 - 0.002 16.9 0.1 0.0034 16.1 0.1 1.4 1 0 0 1 1 1 1 N-acetyltransferase B complex (NatB) non catalytic subunit Whib PF02467.11 AIO02145.1 - 0.32 11.3 2.7 3.7 7.9 0.8 3.0 3 0 0 3 3 3 0 Transcription factor WhiB SAP PF02037.22 AIO02146.1 - 3e-12 45.7 0.1 6.1e-12 44.7 0.1 1.5 1 0 0 1 1 1 1 SAP domain MRI PF15325.1 AIO02146.1 - 0.77 10.7 4.7 1.1 10.2 1.7 2.3 2 0 0 2 2 2 0 Modulator of retrovirus infection TPR_11 PF13414.1 AIO02147.1 - 2.2e-44 148.9 12.3 4.4e-16 58.2 0.3 4.1 3 1 1 4 4 4 4 TPR repeat TPR_1 PF00515.23 AIO02147.1 - 6.9e-38 126.7 12.7 1.9e-07 30.3 0.1 6.4 6 0 0 6 6 6 6 Tetratricopeptide repeat TPR_2 PF07719.12 AIO02147.1 - 4e-32 107.5 9.7 3.3e-06 26.6 0.0 6.1 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_8 PF13181.1 AIO02147.1 - 1.6e-17 61.9 7.6 2.5e-05 23.7 0.0 6.1 5 1 1 6 6 6 4 Tetratricopeptide repeat TPR_14 PF13428.1 AIO02147.1 - 1.2e-14 53.4 0.6 0.0023 18.4 0.0 5.3 3 2 2 5 5 5 3 Tetratricopeptide repeat TPR_12 PF13424.1 AIO02147.1 - 2.1e-14 53.2 7.7 0.00044 20.1 0.0 4.4 2 2 3 5 5 5 3 Tetratricopeptide repeat TPR_16 PF13432.1 AIO02147.1 - 3.8e-14 52.9 2.1 0.024 15.3 0.0 4.2 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_7 PF13176.1 AIO02147.1 - 5.2e-12 44.6 2.8 0.0003 20.3 0.0 5.0 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_17 PF13431.1 AIO02147.1 - 6.2e-12 44.7 8.1 0.03 14.5 0.1 6.6 7 0 0 7 7 6 3 Tetratricopeptide repeat TPR_6 PF13174.1 AIO02147.1 - 1.8e-11 43.7 4.9 0.0065 16.8 0.0 5.1 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_19 PF14559.1 AIO02147.1 - 4.5e-09 36.5 4.3 0.037 14.3 0.0 4.1 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_9 PF13371.1 AIO02147.1 - 1.2e-08 34.6 1.1 0.029 14.2 0.0 3.9 4 0 0 4 4 4 2 Tetratricopeptide repeat MIT PF04212.13 AIO02147.1 - 7.1e-08 32.2 10.1 0.0089 15.8 0.1 4.7 4 1 0 4 4 4 3 MIT (microtubule interacting and transport) domain Apc3 PF12895.2 AIO02147.1 - 2.2e-06 27.7 4.4 0.023 14.8 0.5 2.9 2 1 1 3 3 3 3 Anaphase-promoting complex, cyclosome, subunit 3 DUF3856 PF12968.2 AIO02147.1 - 3.1e-05 23.8 3.9 0.03 14.1 0.2 3.3 2 1 0 2 2 2 2 Domain of Unknown Function (DUF3856) SHNi-TPR PF10516.4 AIO02147.1 - 8.1e-05 21.7 1.2 0.086 12.0 0.0 4.3 5 0 0 5 5 5 1 SHNi-TPR Sel1 PF08238.7 AIO02147.1 - 0.00096 19.7 8.8 0.22 12.2 0.1 4.2 3 1 1 4 4 4 1 Sel1 repeat TPR_10 PF13374.1 AIO02147.1 - 0.001 18.9 2.7 0.084 12.8 0.0 4.0 5 0 0 5 5 4 1 Tetratricopeptide repeat SPO22 PF08631.5 AIO02147.1 - 0.0049 15.9 1.1 0.22 10.5 0.1 2.6 3 0 0 3 3 3 1 Meiosis protein SPO22/ZIP4 like Fis1_TPR_C PF14853.1 AIO02147.1 - 0.013 15.3 0.7 16 5.4 0.0 4.2 4 0 0 4 4 4 0 Fis1 C-terminal tetratricopeptide repeat TPR_3 PF07720.7 AIO02147.1 - 0.031 14.0 3.6 0.16 11.7 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF2225 PF09986.4 AIO02147.1 - 0.099 12.0 4.0 1.1 8.6 0.2 3.1 1 1 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2225) LCM PF04072.9 AIO02148.1 - 6.2e-27 94.3 0.0 7.9e-27 93.9 0.0 1.1 1 0 0 1 1 1 1 Leucine carboxyl methyltransferase DUF1305 PF06996.6 AIO02149.1 - 0.067 12.2 0.0 0.13 11.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1305) IMS PF00817.15 AIO02150.1 - 1.9e-32 112.1 0.0 3.9e-32 111.1 0.0 1.6 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.3 AIO02150.1 - 3.2e-06 27.0 0.0 1.1e-05 25.3 0.0 1.9 2 0 0 2 2 2 1 impB/mucB/samB family C-terminal domain Methyltransf_26 PF13659.1 AIO02150.1 - 0.1 12.6 0.0 0.35 10.9 0.0 2.0 1 1 0 1 1 1 0 Methyltransferase domain Pox_MCEL PF03291.11 AIO02152.1 - 2e-33 115.6 0.0 1.9e-32 112.4 0.0 1.9 1 1 0 1 1 1 1 mRNA capping enzyme Methyltransf_23 PF13489.1 AIO02152.1 - 0.00047 19.9 0.0 0.0016 18.1 0.0 1.8 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 AIO02152.1 - 0.0012 19.4 0.0 0.0026 18.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain NNMT_PNMT_TEMT PF01234.12 AIO02152.1 - 0.002 17.1 0.0 0.068 12.1 0.0 2.1 2 0 0 2 2 2 1 NNMT/PNMT/TEMT family Methyltransf_31 PF13847.1 AIO02152.1 - 0.0076 15.8 0.0 0.075 12.6 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 AIO02152.1 - 0.024 15.1 0.0 0.1 13.0 0.0 2.1 1 1 0 1 1 1 0 Methyltransferase domain PUB PF09409.5 AIO02153.1 - 1.3e-15 56.8 0.0 3.4e-15 55.5 0.0 1.7 1 0 0 1 1 1 1 PUB domain His_Phos_1 PF00300.17 AIO02155.1 - 1.4e-26 93.5 0.0 4.4e-26 91.8 0.0 1.8 2 0 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) His_Phos_2 PF00328.17 AIO02155.1 - 0.12 11.6 0.0 3.5 6.8 0.0 2.4 3 0 0 3 3 3 0 Histidine phosphatase superfamily (branch 2) GTP_EFTU PF00009.22 AIO02158.1 - 2.3e-61 206.5 0.3 3.5e-61 205.9 0.2 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.13 AIO02158.1 - 5.1e-36 122.8 0.0 1.4e-35 121.4 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_C PF00679.19 AIO02158.1 - 5.6e-21 74.2 0.0 2e-20 72.4 0.0 2.0 2 0 0 2 2 2 1 Elongation factor G C-terminus EFG_II PF14492.1 AIO02158.1 - 8.4e-14 51.1 0.1 3.5e-13 49.2 0.0 2.0 2 0 0 2 2 2 1 Elongation Factor G, domain II GTP_EFTU_D2 PF03144.20 AIO02158.1 - 3.7e-12 46.1 0.1 1.1e-11 44.6 0.0 1.9 1 0 0 1 1 1 1 Elongation factor Tu domain 2 Peptidase_S24 PF00717.18 AIO02159.1 - 2.7e-06 26.9 0.0 4.5e-06 26.2 0.0 1.4 1 0 0 1 1 1 1 Peptidase S24-like Peptidase_S26 PF10502.4 AIO02159.1 - 0.0022 17.5 0.0 0.0058 16.1 0.0 1.7 2 0 0 2 2 2 1 Signal peptidase, peptidase S26 SET PF00856.23 AIO02160.1 - 1.4e-07 31.9 0.1 2.5e-06 27.8 0.0 2.3 1 1 0 1 1 1 1 SET domain RimK PF08443.6 AIO02160.1 - 0.13 11.6 0.0 0.21 11.0 0.0 1.2 1 0 0 1 1 1 0 RimK-like ATP-grasp domain Glycos_transf_2 PF00535.21 AIO02161.1 - 3.4e-29 101.6 0.0 4.3e-29 101.3 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.1 AIO02161.1 - 3.9e-05 23.5 0.0 4.9e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 FKBP_C PF00254.23 AIO02162.1 - 2.2e-27 94.8 0.0 2.7e-27 94.6 0.0 1.0 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase CelD_N PF02927.9 AIO02162.1 - 0.046 13.9 0.0 0.057 13.6 0.0 1.2 1 0 0 1 1 1 0 N-terminal ig-like domain of cellulase ADIP PF11559.3 AIO02163.1 - 2e-06 27.7 9.5 2e-06 27.7 6.6 1.8 2 0 0 2 2 2 1 Afadin- and alpha -actinin-Binding DUF4164 PF13747.1 AIO02163.1 - 3.2e-06 27.1 3.9 3.2e-06 27.1 2.7 2.7 2 1 1 3 3 3 1 Domain of unknown function (DUF4164) CENP-F_leu_zip PF10473.4 AIO02163.1 - 5.9e-05 22.9 14.9 5.9e-05 22.9 10.3 1.8 2 0 0 2 2 2 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 TPR_MLP1_2 PF07926.7 AIO02163.1 - 0.0015 18.3 11.5 0.0015 18.3 8.0 2.1 1 1 1 2 2 2 1 TPR/MLP1/MLP2-like protein Sec34 PF04136.10 AIO02163.1 - 0.0081 15.8 5.6 0.0089 15.7 3.1 1.6 2 0 0 2 2 1 1 Sec34-like family bZIP_1 PF00170.16 AIO02163.1 - 0.0088 15.9 0.7 0.0088 15.9 0.5 3.6 2 2 2 4 4 3 1 bZIP transcription factor Orthopox_A5L PF06193.6 AIO02163.1 - 0.0092 15.9 0.1 0.016 15.1 0.0 1.4 1 0 0 1 1 1 1 Orthopoxvirus A5L protein-like Seryl_tRNA_N PF02403.17 AIO02163.1 - 0.01 15.8 7.4 0.01 15.8 5.1 2.1 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain MscS_porin PF12795.2 AIO02163.1 - 0.013 14.8 7.9 0.013 14.8 5.5 2.0 2 0 0 2 2 2 0 Mechanosensitive ion channel porin domain FlaC_arch PF05377.6 AIO02163.1 - 0.017 15.0 0.5 0.017 15.0 0.4 2.1 2 1 1 3 3 1 0 Flagella accessory protein C (FlaC) APG6 PF04111.7 AIO02163.1 - 0.02 13.9 9.4 0.01 14.8 4.5 1.9 2 0 0 2 2 2 0 Autophagy protein Apg6 Atg14 PF10186.4 AIO02163.1 - 0.048 12.6 13.6 0.09 11.7 5.3 2.2 2 0 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 DUF1664 PF07889.7 AIO02163.1 - 0.05 13.4 1.4 0.094 12.5 1.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) DUF342 PF03961.8 AIO02163.1 - 0.054 11.8 5.3 0.08 11.3 3.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Fib_alpha PF08702.5 AIO02163.1 - 0.056 13.5 6.8 0.035 14.2 3.1 1.7 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family GOLGA2L5 PF15070.1 AIO02163.1 - 0.064 11.7 11.6 0.1 11.0 8.0 1.2 1 0 0 1 1 1 0 Putative golgin subfamily A member 2-like protein 5 Stonin2_N PF12016.3 AIO02163.1 - 0.069 12.2 0.0 0.11 11.6 0.0 1.3 1 0 0 1 1 1 0 Stonin 2 Mnd1 PF03962.10 AIO02163.1 - 0.081 12.5 12.4 0.091 12.4 6.1 2.2 2 0 0 2 2 2 0 Mnd1 family TBPIP PF07106.8 AIO02163.1 - 0.085 12.4 11.0 0.033 13.7 5.9 1.6 2 0 0 2 2 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Spectrin PF00435.16 AIO02163.1 - 0.086 13.1 10.4 0.032 14.4 4.0 2.3 2 1 0 2 2 2 0 Spectrin repeat Reo_sigmaC PF04582.7 AIO02163.1 - 0.1 11.7 0.4 0.15 11.2 0.3 1.2 1 0 0 1 1 1 0 Reovirus sigma C capsid protein Phage_GP20 PF06810.6 AIO02163.1 - 0.11 11.9 9.5 0.023 14.1 4.3 1.5 2 0 0 2 2 1 0 Phage minor structural protein GP20 DUF972 PF06156.8 AIO02163.1 - 0.11 12.8 13.0 0.27 11.5 2.8 2.7 2 1 1 3 3 2 0 Protein of unknown function (DUF972) Spc7 PF08317.6 AIO02163.1 - 0.12 11.0 7.8 0.2 10.2 5.4 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein RTBV_P46 PF06216.6 AIO02163.1 - 0.15 10.8 2.8 0.22 10.3 2.0 1.2 1 0 0 1 1 1 0 Rice tungro bacilliform virus P46 protein COG5 PF10392.4 AIO02163.1 - 0.16 11.9 5.4 0.047 13.6 1.9 1.5 2 0 0 2 2 1 0 Golgi transport complex subunit 5 V_ATPase_I PF01496.14 AIO02163.1 - 0.16 9.7 3.7 0.22 9.3 2.6 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family ApoO PF09769.4 AIO02163.1 - 0.51 10.0 2.9 0.37 10.4 0.1 1.9 2 0 0 2 2 2 0 Apolipoprotein O VIT1 PF01988.14 AIO02163.1 - 0.76 9.2 2.9 1.3 8.5 2.0 1.4 1 0 0 1 1 1 0 VIT family STAT_alpha PF01017.15 AIO02163.1 - 0.81 9.3 11.8 0.26 10.9 6.4 1.5 2 0 0 2 2 1 0 STAT protein, all-alpha domain ACCA PF03255.9 AIO02163.1 - 0.96 8.9 6.9 0.68 9.4 3.1 1.9 2 0 0 2 2 2 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit CENP-Q PF13094.1 AIO02163.1 - 1 9.3 15.6 0.51 10.3 7.0 2.3 2 0 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit DivIC PF04977.10 AIO02163.1 - 1.2 8.6 16.4 0.12 11.8 3.4 3.3 2 1 2 4 4 4 0 Septum formation initiator IncA PF04156.9 AIO02163.1 - 1.3 8.5 20.8 0.91 9.0 11.7 2.2 2 1 0 2 2 2 0 IncA protein Rootletin PF15035.1 AIO02163.1 - 1.4 8.8 17.5 3.5 7.5 11.8 1.9 1 1 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion TMF_TATA_bd PF12325.3 AIO02163.1 - 1.4 8.6 17.2 0.13 11.9 5.7 2.7 2 1 1 3 3 3 0 TATA element modulatory factor 1 TATA binding HALZ PF02183.13 AIO02163.1 - 1.5 8.5 14.0 0.58 9.9 2.0 3.6 3 1 1 4 4 4 0 Homeobox associated leucine zipper Syntaxin-6_N PF09177.6 AIO02163.1 - 1.9 8.9 7.1 0.54 10.6 1.5 2.3 2 0 0 2 2 2 0 Syntaxin 6, N-terminal DUF4446 PF14584.1 AIO02163.1 - 2 8.2 6.8 0.19 11.5 1.1 1.9 2 1 0 2 2 1 0 Protein of unknown function (DUF4446) DUF3450 PF11932.3 AIO02163.1 - 2.4 7.3 13.8 0.039 13.2 1.8 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF3450) T2SM PF04612.7 AIO02163.1 - 2.6 7.8 12.0 0.88 9.3 2.6 2.2 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein M Macoilin PF09726.4 AIO02163.1 - 2.6 6.2 12.7 0.11 10.8 4.8 1.4 2 0 0 2 2 2 0 Transmembrane protein AKNA PF12443.3 AIO02163.1 - 3 7.9 8.9 4.7 7.2 3.9 2.8 2 1 0 2 2 2 0 AT-hook-containing transcription factor DUF2968 PF11180.3 AIO02163.1 - 3.6 6.9 20.2 0.16 11.3 7.9 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2968) Kinetocho_Slk19 PF12709.2 AIO02163.1 - 5.1 7.2 12.7 0.35 10.9 1.7 2.9 3 0 0 3 3 3 0 Central kinetochore-associated DinB PF05163.7 AIO02163.1 - 5.6 6.6 8.9 14 5.3 0.2 2.9 2 1 1 3 3 3 0 DinB family COG2 PF06148.6 AIO02163.1 - 6.6 6.6 10.9 2.2 8.1 5.4 1.8 2 1 0 2 2 1 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF4337 PF14235.1 AIO02163.1 - 7 6.4 9.4 10 5.9 3.9 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4337) YlqD PF11068.3 AIO02163.1 - 7.6 6.5 13.6 3.1 7.8 6.9 1.9 2 0 0 2 2 2 0 YlqD protein DUF4407 PF14362.1 AIO02163.1 - 8.7 5.2 10.0 0.86 8.5 2.4 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Spc24 PF08286.6 AIO02163.1 - 8.7 6.0 9.9 1.9 8.2 3.9 2.1 2 1 0 2 2 2 0 Spc24 subunit of Ndc80 TMF_DNA_bd PF12329.3 AIO02163.1 - 8.8 6.2 19.0 1.5 8.7 4.4 2.7 2 1 1 3 3 3 0 TATA element modulatory factor 1 DNA binding DUF607 PF04678.8 AIO02163.1 - 9.4 6.1 9.8 11 5.9 2.8 2.6 2 1 0 2 2 2 0 Protein of unknown function, DUF607 SlyX PF04102.7 AIO02163.1 - 9.6 6.6 11.0 1.7 9.0 1.8 2.8 2 1 0 2 2 2 0 SlyX Paf67 PF10255.4 AIO02164.1 - 1.9e-83 280.6 0.0 2.5e-83 280.2 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase I-associated factor PAF67 TPR_2 PF07719.12 AIO02164.1 - 0.067 13.1 0.0 0.97 9.5 0.0 2.7 3 0 0 3 3 3 0 Tetratricopeptide repeat FGGY_N PF00370.16 AIO02165.1 - 1.5e-13 50.6 0.0 1.8e-13 50.3 0.0 1.0 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain CH PF00307.26 AIO02166.1 - 0.00099 19.1 0.0 0.19 11.8 0.0 3.1 3 0 0 3 3 3 2 Calponin homology (CH) domain TFIIS_M PF07500.9 AIO02167.1 - 2.9e-05 24.1 0.2 5.4e-05 23.2 0.1 1.4 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS), central domain NUDIX PF00293.23 AIO02169.1 - 7.2e-15 54.8 0.0 1.2e-14 54.1 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain ESCRT-II PF05871.7 AIO02170.1 - 8.3e-13 48.4 0.0 3.5e-12 46.4 0.0 1.8 1 1 0 1 1 1 1 ESCRT-II complex subunit DUF3223 PF11523.3 AIO02170.1 - 0.021 15.0 0.4 2.6 8.3 0.0 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF3223) Proteasome PF00227.21 AIO02171.1 - 1.3e-28 99.6 0.0 1.5e-28 99.3 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit RNase_HII PF01351.13 AIO02172.1 - 2.4e-23 82.7 0.0 4e-14 52.7 0.0 3.0 1 1 0 2 2 2 2 Ribonuclease HII Nop10p PF04135.7 AIO02173.1 - 1.9e-20 72.2 0.4 2.1e-20 72.1 0.3 1.1 1 0 0 1 1 1 1 Nucleolar RNA-binding protein, Nop10p family IQ PF00612.22 AIO02174.1 - 0.022 14.3 2.6 0.12 12.1 1.8 2.3 1 0 0 1 1 1 0 IQ calmodulin-binding motif DUF106 PF01956.11 AIO02175.1 - 2.9e-46 157.0 2.6 3.9e-46 156.6 1.8 1.2 1 0 0 1 1 1 1 Integral membrane protein DUF106 PIP5K PF01504.13 AIO02176.1 - 4.3e-65 219.3 0.0 6e-65 218.8 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase Macoilin PF09726.4 AIO02178.1 - 0.22 9.7 12.5 0.28 9.4 8.7 1.1 1 0 0 1 1 1 0 Transmembrane protein DUF4614 PF15391.1 AIO02178.1 - 1.6 8.4 15.8 3.1 7.5 11.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) DUF605 PF04652.11 AIO02178.1 - 2.2 7.5 18.8 3 7.1 13.0 1.2 1 0 0 1 1 1 0 Vta1 like DUF566 PF04484.7 AIO02178.1 - 5.2 6.4 20.3 8.6 5.7 14.1 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF566) PDZ_2 PF13180.1 AIO02179.1 - 2.5e-05 24.0 0.0 5.6e-05 22.9 0.0 1.6 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.19 AIO02179.1 - 0.0018 18.3 0.5 0.0063 16.6 0.0 2.0 2 0 0 2 2 2 1 PDZ domain (Also known as DHR or GLGF) TerB-C PF15615.1 AIO02180.1 - 0.022 15.0 1.2 0.039 14.2 0.8 1.4 1 0 0 1 1 1 0 TerB-C domain MIF PF01187.13 AIO02180.1 - 0.071 13.1 0.1 0.2 11.7 0.0 1.8 2 0 0 2 2 2 0 Macrophage migration inhibitory factor (MIF) Aa_trans PF01490.13 AIO02181.1 - 2e-61 207.7 23.8 2.3e-61 207.4 16.5 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.8 AIO02181.1 - 5.5e-09 35.3 15.9 5.5e-09 35.3 11.0 1.8 2 0 0 2 2 2 1 Tryptophan/tyrosine permease family TFIIA_gamma_C PF02751.9 AIO02182.1 - 0.0098 15.6 0.0 0.016 15.0 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit W2 PF02020.13 AIO02183.1 - 0.036 14.0 0.1 0.82 9.6 0.0 2.6 2 0 0 2 2 2 0 eIF4-gamma/eIF5/eIF2-epsilon Sec1 PF00995.18 AIO02185.1 - 5.2e-128 428.1 0.3 6.1e-128 427.9 0.2 1.0 1 0 0 1 1 1 1 Sec1 family Dus PF01207.12 AIO02186.1 - 3e-35 121.5 1.2 3.9e-31 108.0 0.1 2.3 2 1 0 2 2 2 2 Dihydrouridine synthase (Dus) zf-Apc11 PF12861.2 AIO02187.1 - 0.018 14.9 0.8 0.032 14.0 0.6 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C2HC_2 PF13913.1 AIO02188.1 - 1.7e-16 59.4 6.7 1.3e-09 37.5 0.9 2.3 2 0 0 2 2 2 2 zinc-finger of a C2HC-type zf-H2C2_2 PF13465.1 AIO02188.1 - 0.008 16.4 0.5 1.1 9.6 0.1 2.4 2 0 0 2 2 2 1 Zinc-finger double domain Aft1_HRR PF11787.3 AIO02188.1 - 0.054 14.5 0.3 0.16 12.9 0.2 1.8 1 0 0 1 1 1 0 Aft1 HRR domain Sgf11 PF08209.6 AIO02188.1 - 0.31 10.3 4.6 2.8 7.3 0.8 2.4 2 0 0 2 2 2 0 Sgf11 (transcriptional regulation protein) zf-C2H2 PF00096.21 AIO02188.1 - 0.64 10.4 4.0 7.5 7.1 0.8 2.5 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 AIO02188.1 - 0.96 9.9 5.7 20 5.8 1.3 3.2 3 1 0 3 3 3 0 C2H2-type zinc finger zf-C2H2_6 PF13912.1 AIO02188.1 - 1 9.3 5.1 2.1 8.3 0.5 2.4 2 0 0 2 2 2 0 C2H2-type zinc finger TPR_11 PF13414.1 AIO02189.1 - 2.7e-33 113.4 29.2 3e-18 65.2 3.3 5.3 3 2 2 5 5 5 5 TPR repeat DnaJ PF00226.26 AIO02189.1 - 1.4e-20 72.7 2.3 1.5e-20 72.6 0.3 2.1 2 0 0 2 2 1 1 DnaJ domain TPR_2 PF07719.12 AIO02189.1 - 1.2e-14 52.9 31.1 6.5e-05 22.5 0.1 7.9 8 1 0 8 8 8 4 Tetratricopeptide repeat TPR_19 PF14559.1 AIO02189.1 - 5.8e-10 39.3 16.2 0.0048 17.1 1.9 5.8 3 2 2 6 6 6 4 Tetratricopeptide repeat TPR_14 PF13428.1 AIO02189.1 - 6.3e-10 38.8 28.5 0.11 13.1 0.1 8.1 6 2 3 9 9 9 4 Tetratricopeptide repeat TPR_1 PF00515.23 AIO02189.1 - 4.7e-09 35.4 29.3 0.0011 18.5 0.4 7.2 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_16 PF13432.1 AIO02189.1 - 4.1e-08 33.6 29.2 6.8e-06 26.6 2.8 6.3 3 2 3 7 7 7 2 Tetratricopeptide repeat TPR_9 PF13371.1 AIO02189.1 - 1.5e-06 27.9 10.1 0.0013 18.5 0.2 4.7 4 1 1 5 5 4 1 Tetratricopeptide repeat TPR_17 PF13431.1 AIO02189.1 - 0.0007 19.5 15.4 0.0017 18.3 0.4 6.5 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_12 PF13424.1 AIO02189.1 - 0.00084 19.2 22.6 0.0037 17.1 1.8 5.3 2 2 3 5 5 5 1 Tetratricopeptide repeat TPR_7 PF13176.1 AIO02189.1 - 0.002 17.7 9.8 3.5 7.6 0.0 5.4 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_8 PF13181.1 AIO02189.1 - 0.0073 16.0 20.2 0.42 10.5 0.1 6.1 7 0 0 7 7 5 2 Tetratricopeptide repeat DUF2408 PF10303.4 AIO02189.1 - 0.0086 16.1 1.3 0.45 10.6 0.1 2.6 2 0 0 2 2 2 1 Protein of unknown function (DUF2408) Phage_term_smal PF05944.7 AIO02189.1 - 0.02 14.5 2.0 1.3 8.6 0.2 2.6 2 0 0 2 2 2 0 Phage small terminase subunit DUF45 PF01863.12 AIO02189.1 - 0.054 13.2 3.7 0.064 13.0 2.0 1.5 1 1 0 1 1 1 0 Protein of unknown function DUF45 Fis1_TPR_C PF14853.1 AIO02189.1 - 0.62 9.9 5.9 1.1 9.1 0.2 3.7 4 0 0 4 4 4 0 Fis1 C-terminal tetratricopeptide repeat TPR_6 PF13174.1 AIO02189.1 - 1.5 9.4 22.0 2.1 8.9 0.2 6.7 6 1 1 7 7 7 0 Tetratricopeptide repeat SHNi-TPR PF10516.4 AIO02189.1 - 7.7 5.8 8.3 15 4.9 0.2 3.6 4 0 0 4 4 4 0 SHNi-TPR Mito_carr PF00153.22 AIO02190.1 - 3.4e-90 295.9 19.2 4.4e-21 74.4 0.1 6.2 5 1 1 6 6 6 6 Mitochondrial carrier protein PP2C PF00481.16 AIO02192.1 - 3.7e-68 229.6 0.6 4.6e-68 229.3 0.4 1.0 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.1 AIO02192.1 - 0.00034 20.0 0.0 0.00089 18.7 0.0 1.7 1 1 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.7 AIO02192.1 - 0.01 15.5 0.0 0.37 10.4 0.0 2.2 2 0 0 2 2 2 1 Stage II sporulation protein E (SpoIIE) LSM PF01423.17 AIO02193.1 - 1.5e-06 27.6 0.2 2.4e-06 26.9 0.1 1.3 1 0 0 1 1 1 1 LSM domain ubiquitin PF00240.18 AIO02195.1 - 3.4e-12 45.5 0.0 6.5e-12 44.6 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family UBA PF00627.26 AIO02195.1 - 1.7e-07 30.8 0.3 7.1e-07 28.8 0.2 2.2 1 0 0 1 1 1 1 UBA/TS-N domain Rad60-SLD PF11976.3 AIO02195.1 - 3.6e-06 26.5 0.1 5.8e-06 25.9 0.1 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 AIO02195.1 - 0.0053 16.9 0.2 0.015 15.5 0.0 1.9 2 1 0 2 2 2 1 Ubiquitin-like domain XPC-binding PF09280.6 AIO02195.1 - 0.034 13.6 17.6 0.12 11.8 12.2 2.0 1 0 0 1 1 1 0 XPC-binding domain Rad60-SLD_2 PF13881.1 AIO02195.1 - 0.046 13.6 0.2 0.12 12.2 0.1 1.7 1 1 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 AIO02195.1 - 0.12 12.5 0.0 0.2 11.8 0.0 1.4 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain Pkinase PF00069.20 AIO02196.1 - 4e-78 262.1 0.0 4.5e-78 261.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AIO02196.1 - 3.9e-36 124.4 0.0 9.7e-36 123.1 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.18 AIO02196.1 - 0.0029 17.3 0.3 0.064 12.9 0.0 2.5 2 1 1 3 3 3 1 Phosphotransferase enzyme family Kinase-like PF14531.1 AIO02196.1 - 0.068 12.1 0.0 6 5.7 0.0 2.3 2 0 0 2 2 2 0 Kinase-like FAM91_C PF14648.1 AIO02197.1 - 0.061 12.1 1.4 0.095 11.5 0.7 1.6 1 1 0 1 1 1 0 FAM91 C-terminus Nitrate_red_del PF02613.10 AIO02197.1 - 0.24 11.2 6.7 1.1 9.0 0.1 3.2 2 1 1 3 3 3 0 Nitrate reductase delta subunit DUF465 PF04325.8 AIO02197.1 - 0.34 10.6 9.5 1.2 8.8 0.0 4.1 3 1 0 3 3 3 0 Protein of unknown function (DUF465) DUF972 PF06156.8 AIO02197.1 - 0.39 11.0 21.0 0.43 10.9 2.0 3.7 2 1 1 3 3 3 0 Protein of unknown function (DUF972) DUF641 PF04859.7 AIO02197.1 - 1.7 8.4 15.1 0.03 14.0 2.1 3.0 1 1 2 3 3 3 0 Plant protein of unknown function (DUF641) ATG16 PF08614.6 AIO02197.1 - 3.6 7.3 34.5 0.39 10.5 14.3 2.2 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) Sec20 PF03908.8 AIO02197.1 - 4.1 7.1 8.9 0.9 9.2 0.3 3.2 2 1 0 3 3 3 0 Sec20 GTP_EFTU PF00009.22 AIO02198.1 - 1.6e-59 200.4 0.0 2.7e-59 199.7 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_II PF14492.1 AIO02198.1 - 3.7e-23 81.1 0.0 9.3e-23 79.8 0.0 1.8 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_C PF00679.19 AIO02198.1 - 1.2e-20 73.1 0.1 2.8e-20 71.9 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_IV PF03764.13 AIO02198.1 - 1.7e-15 56.6 0.0 4e-15 55.4 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G, domain IV GTP_EFTU_D2 PF03144.20 AIO02198.1 - 4.5e-07 29.8 0.2 2.3e-06 27.6 0.0 2.3 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 AIO02198.1 - 0.012 15.5 0.0 0.027 14.4 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase DUF442 PF04273.8 AIO02198.1 - 0.019 14.8 0.0 0.52 10.1 0.0 2.5 2 0 0 2 2 2 0 Putative phosphatase (DUF442) AIG1 PF04548.11 AIO02198.1 - 0.03 13.4 0.0 0.061 12.4 0.0 1.4 1 0 0 1 1 1 0 AIG1 family DUF148 PF02520.12 AIO02198.1 - 0.034 13.9 0.1 0.089 12.5 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function DUF148 IF4E PF01652.13 AIO02199.1 - 1.4e-08 34.4 0.0 1.7e-08 34.1 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E Ribosomal_S27 PF01599.14 AIO02200.1 - 1.7e-20 72.5 3.7 3.4e-20 71.5 2.5 1.6 1 0 0 1 1 1 1 Ribosomal protein S27a Rad60-SLD PF11976.3 AIO02200.1 - 1.8e-06 27.5 0.0 3.6e-05 23.3 0.0 2.4 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.18 AIO02200.1 - 2.6e-06 26.7 0.0 0.00016 21.0 0.0 2.8 2 1 0 2 2 2 1 Ubiquitin family IBR PF01485.16 AIO02200.1 - 0.0026 17.6 0.8 0.0041 16.9 0.6 1.3 1 0 0 1 1 1 1 IBR domain DnaJ PF00226.26 AIO02201.1 - 1.6e-21 75.7 0.3 3e-21 74.9 0.2 1.5 1 0 0 1 1 1 1 DnaJ domain DALR_2 PF09190.6 AIO02201.1 - 0.11 12.7 0.4 8.2 6.7 0.0 3.0 3 0 0 3 3 3 0 DALR domain ATP-synt_Eps PF04627.8 AIO02202.1 - 1.2e-06 28.0 0.1 2.1e-06 27.1 0.1 1.6 1 1 0 1 1 1 1 Mitochondrial ATP synthase epsilon chain DUF3592 PF12158.3 AIO02203.1 - 1.1e-13 51.2 0.5 1.2e-13 51.1 0.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3592) RNase_HII PF01351.13 AIO02204.1 - 1.3e-39 135.9 0.0 1.6e-39 135.6 0.0 1.1 1 0 0 1 1 1 1 Ribonuclease HII PIG-U PF06728.8 AIO02205.1 - 9.7e-06 24.6 22.7 2.8e-05 23.1 13.5 2.6 2 1 0 2 2 2 1 GPI transamidase subunit PIG-U EamA PF00892.15 AIO02207.1 - 1.3e-06 28.4 23.6 7.9e-06 25.9 0.8 4.0 5 0 0 5 5 5 2 EamA-like transporter family DUF914 PF06027.7 AIO02207.1 - 1.1e-05 24.5 0.3 1.1e-05 24.5 0.2 2.4 3 0 0 3 3 3 2 Eukaryotic protein of unknown function (DUF914) UAA PF08449.6 AIO02207.1 - 0.00012 21.1 14.7 0.0046 15.9 0.1 2.5 3 0 0 3 3 3 2 UAA transporter family TPT PF03151.11 AIO02207.1 - 7.9 6.1 20.7 0.028 14.0 4.0 2.9 3 1 0 3 3 3 0 Triose-phosphate Transporter family SSB PF00436.20 AIO02210.1 - 2e-05 24.4 0.0 2.9e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 Single-strand binding protein family LRR_4 PF12799.2 AIO02211.1 - 7.1e-13 47.8 0.1 1.7e-05 24.3 0.0 3.2 2 1 0 2 2 2 2 Leucine Rich repeats (2 copies) LRR_9 PF14580.1 AIO02211.1 - 4.2e-10 39.4 0.1 1.1e-09 38.0 0.0 1.7 1 1 0 1 1 1 1 Leucine-rich repeat LRR_8 PF13855.1 AIO02211.1 - 1.7e-07 30.8 1.0 1.4e-06 27.9 0.1 2.6 1 1 0 2 2 2 1 Leucine rich repeat Cactin_mid PF10312.4 AIO02211.1 - 0.0034 16.6 0.1 0.33 10.1 0.2 2.2 2 0 0 2 2 2 1 Conserved mid region of cactin LRR_7 PF13504.1 AIO02211.1 - 0.012 15.6 1.8 26 5.5 0.0 4.9 5 0 0 5 5 5 0 Leucine rich repeat LRR_1 PF00560.28 AIO02211.1 - 0.035 14.1 0.9 35 4.9 0.0 4.0 5 0 0 5 5 5 0 Leucine Rich Repeat Nyv1_N PF09426.5 AIO02211.1 - 0.059 12.9 0.0 0.11 12.0 0.0 1.5 1 0 0 1 1 1 0 Vacuolar R-SNARE Nyv1 N terminal BBIP10 PF14777.1 AIO02211.1 - 0.08 12.3 1.1 0.24 10.7 0.6 1.9 2 0 0 2 2 2 0 Cilia BBSome complex subunit 10 Pol_alpha_B_N PF08418.5 AIO02211.1 - 4.4 6.7 8.4 8.8 5.7 0.4 2.1 2 0 0 2 2 2 0 DNA polymerase alpha subunit B N-terminal Pkinase PF00069.20 AIO02212.1 - 8e-74 248.0 0.0 1e-73 247.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AIO02212.1 - 2.4e-35 121.8 0.0 3.3e-35 121.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 AIO02212.1 - 0.0004 19.4 0.0 0.00059 18.8 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 AIO02212.1 - 0.00065 18.8 1.6 0.0013 17.8 1.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 AIO02212.1 - 0.05 13.3 0.6 0.16 11.6 0.0 2.0 2 0 0 2 2 2 0 Phosphotransferase enzyme family FeoB_N PF02421.13 AIO02212.1 - 0.11 11.7 0.3 0.25 10.6 0.2 1.5 1 1 0 1 1 1 0 Ferrous iron transport protein B zf-CCCH_2 PF14608.1 AIO02213.1 - 0.0032 17.4 2.3 1.1 9.3 0.2 3.0 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type NTPase_P4 PF11602.3 AIO02213.1 - 0.068 12.1 0.3 0.1 11.5 0.2 1.2 1 0 0 1 1 1 0 ATPase P4 of dsRNA bacteriophage phi-12 zf-CCCH PF00642.19 AIO02213.1 - 0.21 11.3 18.4 0.15 11.8 0.3 4.0 4 0 0 4 4 4 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH PF00642.19 AIO02214.1 - 0.07 12.8 1.1 0.18 11.5 0.7 1.7 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) XPC-binding PF09280.6 AIO02215.1 - 7.9e-05 22.0 0.0 7.9e-05 22.0 0.0 2.0 2 0 0 2 2 2 1 XPC-binding domain TPR_11 PF13414.1 AIO02216.1 - 1.2e-21 76.0 12.4 4.5e-11 42.2 1.3 6.3 5 2 2 7 7 7 3 TPR repeat TPR_1 PF00515.23 AIO02216.1 - 4.4e-13 48.2 0.4 0.0017 17.8 0.0 6.0 6 0 0 6 6 6 3 Tetratricopeptide repeat DnaJ PF00226.26 AIO02216.1 - 1.3e-09 37.6 0.1 4.3e-09 35.9 0.1 1.8 1 0 0 1 1 1 1 DnaJ domain TPR_2 PF07719.12 AIO02216.1 - 2.7e-08 33.0 28.9 0.051 13.5 0.0 7.8 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_7 PF13176.1 AIO02216.1 - 0.00057 19.4 6.1 0.34 10.8 0.1 4.5 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_9 PF13371.1 AIO02216.1 - 0.0013 18.5 33.3 0.3 10.9 0.6 6.2 5 1 1 6 6 6 5 Tetratricopeptide repeat TPR_8 PF13181.1 AIO02216.1 - 0.0032 17.1 1.1 24 5.0 0.0 5.0 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_17 PF13431.1 AIO02216.1 - 0.0055 16.8 1.9 56 4.3 0.0 4.5 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.1 AIO02216.1 - 0.24 12.1 37.1 0.31 11.7 0.7 7.1 5 2 2 7 7 7 0 Tetratricopeptide repeat TPR_16 PF13432.1 AIO02216.1 - 2 9.1 46.5 0.42 11.3 1.1 6.3 5 1 1 6 6 6 0 Tetratricopeptide repeat Peptidase_C2 PF00648.16 AIO02218.1 - 6.8e-19 67.9 0.0 1.3e-18 67.0 0.0 1.4 1 0 0 1 1 1 1 Calpain family cysteine protease Saccharop_dh PF03435.13 AIO02218.1 - 0.13 11.2 0.0 0.22 10.4 0.0 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase MEDS PF14417.1 AIO02218.1 - 0.19 10.7 0.7 0.64 9.0 0.0 2.1 3 0 0 3 3 3 0 MEDS: MEthanogen/methylotroph, DcmR Sensory domain Tfb2 PF03849.9 AIO02220.1 - 2.2e-19 69.3 0.0 5e-19 68.1 0.0 1.5 1 1 0 1 1 1 1 Transcription factor Tfb2 Helicase_C_3 PF13625.1 AIO02220.1 - 6.1e-09 35.7 0.3 1.6e-06 27.9 0.0 2.7 2 0 0 2 2 2 2 Helicase conserved C-terminal domain Arf PF00025.16 AIO02222.1 - 5.4e-31 107.1 0.0 7.5e-31 106.7 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.17 AIO02222.1 - 6.3e-09 35.4 0.0 1e-08 34.7 0.0 1.3 1 0 0 1 1 1 1 Ras family SRPRB PF09439.5 AIO02222.1 - 3.7e-08 32.8 0.0 5.7e-08 32.1 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.15 AIO02222.1 - 1.2e-07 30.7 0.0 1.6e-06 27.0 0.0 2.1 1 1 0 2 2 2 1 G-protein alpha subunit GTP_EFTU PF00009.22 AIO02222.1 - 0.0022 17.4 0.0 0.0038 16.6 0.0 1.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain cNMP_binding PF00027.24 AIO02223.1 - 1.6e-22 79.1 0.1 2.2e-12 46.6 0.0 4.5 4 1 0 4 4 4 3 Cyclic nucleotide-binding domain C2 PF00168.25 AIO02223.1 - 2.4e-05 24.0 0.0 0.00033 20.4 0.0 2.9 3 0 0 3 3 3 1 C2 domain zf-CCCH PF00642.19 AIO02224.1 - 1.1 9.0 19.3 0.13 12.0 0.2 3.7 4 0 0 4 4 4 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) LRV_FeS PF05484.6 AIO02224.1 - 2 8.0 7.1 6.5 6.4 0.9 2.6 2 0 0 2 2 2 0 LRV protein FeS4 cluster TMF_DNA_bd PF12329.3 AIO02225.1 - 0.047 13.4 8.1 0.61 9.9 2.0 2.5 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding DivIC PF04977.10 AIO02225.1 - 0.081 12.4 7.3 0.075 12.5 0.9 2.4 2 0 0 2 2 2 0 Septum formation initiator bZIP_1 PF00170.16 AIO02225.1 - 0.29 11.1 4.3 0.75 9.8 0.7 2.4 2 0 0 2 2 2 0 bZIP transcription factor DUF3373 PF11853.3 AIO02225.1 - 0.75 8.2 6.6 0.26 9.7 2.6 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF3373) Uds1 PF15456.1 AIO02225.1 - 0.98 9.4 17.3 0.054 13.4 6.6 2.3 1 1 1 2 2 2 0 Up-regulated During Septation DUF972 PF06156.8 AIO02225.1 - 1.1 9.6 5.6 4.3 7.7 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF972) V_ATPase_I PF01496.14 AIO02225.1 - 1.3 6.7 2.1 1.8 6.2 1.5 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family SlyX PF04102.7 AIO02225.1 - 4.8 7.6 11.8 7.4 7.0 1.7 2.9 2 0 0 2 2 2 0 SlyX Striatin PF08232.7 AIO02225.1 - 8.6 6.6 11.6 18 5.6 8.0 1.5 1 0 0 1 1 1 0 Striatin family Pkinase PF00069.20 AIO02226.1 - 1.1e-50 172.2 0.0 1.5e-50 171.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AIO02226.1 - 7.3e-31 107.1 0.0 1e-30 106.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 AIO02226.1 - 0.00045 20.0 0.8 0.19 11.4 0.0 2.8 2 1 1 3 3 3 2 Phosphotransferase enzyme family Kinase-like PF14531.1 AIO02226.1 - 0.036 13.0 0.0 0.06 12.2 0.0 1.3 1 0 0 1 1 1 0 Kinase-like HA2 PF04408.18 AIO02227.1 - 6.3e-18 64.6 0.0 1.6e-17 63.3 0.0 1.7 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.26 AIO02227.1 - 1.2e-14 53.9 0.0 2.9e-14 52.6 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain OB_NTP_bind PF07717.11 AIO02227.1 - 7.1e-11 41.9 0.0 1.7e-10 40.7 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold DEAD PF00270.24 AIO02227.1 - 2.9e-09 36.6 0.0 1.6e-08 34.2 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase T2SE PF00437.15 AIO02227.1 - 4.1e-05 22.6 0.0 9.4e-05 21.4 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_22 PF13401.1 AIO02227.1 - 0.0006 19.9 0.1 0.005 16.9 0.1 2.4 1 1 0 1 1 1 1 AAA domain KaiC PF06745.8 AIO02227.1 - 0.0035 16.5 0.0 0.0073 15.4 0.0 1.5 1 0 0 1 1 1 1 KaiC Sigma54_activ_2 PF14532.1 AIO02227.1 - 0.0043 17.0 0.0 0.27 11.2 0.0 3.0 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_19 PF13245.1 AIO02227.1 - 0.014 15.1 0.0 0.1 12.3 0.0 2.6 2 0 0 2 2 2 0 Part of AAA domain AAA_25 PF13481.1 AIO02227.1 - 0.028 13.8 0.2 0.16 11.3 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.1 AIO02227.1 - 0.043 14.1 0.0 0.086 13.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_10 PF12846.2 AIO02227.1 - 0.061 12.7 0.0 3.1 7.1 0.0 2.5 2 0 0 2 2 2 0 AAA-like domain NACHT PF05729.7 AIO02227.1 - 0.088 12.4 0.1 0.41 10.2 0.1 2.2 2 0 0 2 2 2 0 NACHT domain PhoH PF02562.11 AIO02227.1 - 0.096 11.9 0.0 0.22 10.7 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein NB-ARC PF00931.17 AIO02227.1 - 0.12 11.2 0.0 0.89 8.3 0.0 2.1 2 0 0 2 2 2 0 NB-ARC domain AAA_29 PF13555.1 AIO02227.1 - 0.13 11.8 0.0 0.28 10.7 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.22 AIO02227.1 - 0.16 12.2 0.0 0.41 10.9 0.0 1.6 1 0 0 1 1 1 0 ABC transporter NifU PF01106.12 AIO02228.1 - 1.1e-19 70.0 0.0 2.5e-19 68.7 0.0 1.7 2 0 0 2 2 2 1 NifU-like domain Nfu_N PF08712.6 AIO02228.1 - 2.2e-06 27.1 0.0 6.1e-06 25.7 0.0 1.7 1 0 0 1 1 1 1 Scaffold protein Nfu/NifU N terminal Glyco_transf_25 PF01755.12 AIO02228.1 - 0.0096 15.5 0.1 0.048 13.2 0.0 1.9 2 0 0 2 2 2 1 Glycosyltransferase family 25 (LPS biosynthesis protein) eIF-6 PF01912.13 AIO02229.1 - 9.9e-82 272.8 0.3 1.5e-81 272.2 0.2 1.3 1 0 0 1 1 1 1 eIF-6 family Pkinase PF00069.20 AIO02230.1 - 4.2e-72 242.4 0.0 7.8e-72 241.5 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AIO02230.1 - 6.6e-40 136.8 0.0 1e-39 136.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 AIO02230.1 - 1.2e-06 27.7 0.0 2.1e-06 26.9 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 AIO02230.1 - 0.00046 19.3 0.2 0.0013 17.8 0.1 1.7 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 AIO02230.1 - 0.0029 16.9 0.8 0.0058 15.9 0.2 1.7 2 0 0 2 2 2 1 PhoP regulatory network protein YrbL APH PF01636.18 AIO02230.1 - 0.0049 16.6 0.1 0.44 10.2 0.0 2.4 1 1 1 2 2 2 2 Phosphotransferase enzyme family Pkinase PF00069.20 AIO02231.1 - 8e-55 185.7 0.0 1.4e-54 185.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AIO02231.1 - 2e-32 112.3 0.0 3.6e-32 111.4 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 AIO02231.1 - 0.0022 17.7 0.0 0.0052 16.5 0.0 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family ETRAMP PF09716.5 AIO02231.1 - 0.029 14.3 0.0 0.099 12.6 0.0 1.9 2 0 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) Ribonuclease_3 PF00636.21 AIO02232.1 - 0.0004 20.7 0.0 0.009 16.4 0.0 2.9 3 1 0 3 3 3 1 Ribonuclease III domain Ribosomal_S13 PF00416.17 AIO02233.1 - 9.7e-30 103.1 0.2 1.2e-29 102.9 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein S13/S18 DUF4004 PF13171.1 AIO02233.1 - 0.017 15.3 0.0 0.025 14.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4004) Ribosomal_S13 PF00416.17 AIO02234.1 - 9.7e-30 103.1 0.2 1.2e-29 102.9 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein S13/S18 DUF4004 PF13171.1 AIO02234.1 - 0.017 15.3 0.0 0.025 14.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4004) Dynein_heavy PF03028.10 AIO02235.1 - 1.2e-217 724.3 4.4 5.3e-216 718.9 0.0 3.5 4 0 0 4 4 4 2 Dynein heavy chain and region D6 of dynein motor DHC_N2 PF08393.8 AIO02235.1 - 2.1e-122 408.5 10.7 2.1e-122 408.5 7.4 2.8 2 0 0 2 2 2 1 Dynein heavy chain, N-terminal region 2 AAA_6 PF12774.2 AIO02235.1 - 1.4e-92 309.3 0.3 5.5e-92 307.4 0.0 2.1 2 0 0 2 2 2 1 Hydrolytic ATP binding site of dynein motor region D1 AAA_8 PF12780.2 AIO02235.1 - 1.4e-69 234.0 0.1 3.5e-69 232.7 0.1 1.7 2 0 0 2 2 2 1 P-loop containing dynein motor region D4 AAA_9 PF12781.2 AIO02235.1 - 1.8e-54 183.9 0.1 3.9e-54 182.8 0.1 1.6 1 0 0 1 1 1 1 ATP-binding dynein motor region D5 MT PF12777.2 AIO02235.1 - 3.2e-45 154.3 7.8 3.2e-45 154.3 5.4 1.8 2 0 0 2 2 2 1 Microtubule-binding stalk of dynein motor AAA_7 PF12775.2 AIO02235.1 - 1.1e-36 126.3 0.0 2.1e-36 125.4 0.0 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region D3 AAA_5 PF07728.9 AIO02235.1 - 4.4e-16 58.8 0.7 5.6e-05 22.8 0.0 7.5 8 2 0 8 8 7 3 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 AIO02235.1 - 2.2e-10 40.7 0.0 1.4e-06 28.4 0.0 4.4 4 1 1 5 5 3 1 AAA domain AAA PF00004.24 AIO02235.1 - 4.4e-06 26.9 0.0 0.14 12.3 0.0 3.4 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.17 AIO02235.1 - 2e-05 24.7 0.1 0.28 11.3 0.0 4.1 4 0 0 4 4 4 2 RNA helicase AAA_16 PF13191.1 AIO02235.1 - 6.8e-05 22.9 2.0 1.1 9.2 0.0 4.7 4 0 0 4 4 3 2 AAA ATPase domain NACHT PF05729.7 AIO02235.1 - 7.1e-05 22.5 1.0 0.0028 17.3 0.0 3.6 3 0 0 3 3 2 1 NACHT domain AAA_10 PF12846.2 AIO02235.1 - 0.00066 19.2 0.4 0.1 12.0 0.0 3.8 4 0 0 4 4 4 1 AAA-like domain AAA_14 PF13173.1 AIO02235.1 - 0.0019 18.1 0.0 2.1 8.2 0.0 3.4 3 0 0 3 3 2 1 AAA domain MutS_III PF05192.13 AIO02235.1 - 0.007 16.1 9.5 0.38 10.5 2.5 3.7 2 1 0 2 2 2 2 MutS domain III AAA_33 PF13671.1 AIO02235.1 - 0.012 15.4 0.2 1.4 8.7 0.0 3.5 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.1 AIO02235.1 - 0.014 16.1 0.0 2.1 9.2 0.0 3.6 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.1 AIO02235.1 - 0.04 13.6 0.9 2.5 7.9 0.1 3.4 3 0 0 3 3 3 0 Part of AAA domain AAA_18 PF13238.1 AIO02235.1 - 0.19 12.0 0.0 11 6.3 0.0 3.2 2 0 0 2 2 2 0 AAA domain MobB PF03205.9 AIO02235.1 - 0.41 10.3 0.1 6.9 6.3 0.0 2.6 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B Gp58 PF07902.6 AIO02235.1 - 0.6 8.2 0.4 1.3 7.1 0.3 1.5 1 0 0 1 1 1 0 gp58-like protein IncA PF04156.9 AIO02235.1 - 4.1 6.9 36.1 0.49 9.9 3.0 4.2 3 0 0 3 3 3 0 IncA protein DUF148 PF02520.12 AIO02237.1 - 0.035 13.9 0.4 0.057 13.2 0.3 1.3 1 0 0 1 1 1 0 Domain of unknown function DUF148 S10_plectin PF03501.10 AIO02238.1 - 5.3e-35 119.1 0.0 6.4e-35 118.8 0.0 1.1 1 0 0 1 1 1 1 Plectin/S10 domain S10_plectin PF03501.10 AIO02239.1 - 5.3e-35 119.1 0.0 6.4e-35 118.8 0.0 1.1 1 0 0 1 1 1 1 Plectin/S10 domain WD40 PF00400.27 AIO02240.1 - 1.4e-13 50.1 20.1 1e-10 41.0 0.1 7.7 9 0 0 9 9 9 1 WD domain, G-beta repeat Clathrin PF00637.15 AIO02240.1 - 0.00011 21.7 0.6 0.17 11.4 0.0 3.7 2 1 2 4 4 4 2 Region in Clathrin and VPS Coatomer_WDAD PF04053.9 AIO02240.1 - 0.00027 19.8 0.0 0.036 12.8 0.0 3.9 3 1 1 4 4 4 1 Coatomer WD associated region TPR_7 PF13176.1 AIO02240.1 - 0.0014 18.2 1.9 1.5 8.8 0.0 4.6 5 1 0 5 5 5 1 Tetratricopeptide repeat TPR_14 PF13428.1 AIO02240.1 - 0.0027 18.2 7.2 5.8 7.8 0.0 5.5 4 3 3 7 7 5 1 Tetratricopeptide repeat SNAP PF14938.1 AIO02240.1 - 0.0075 15.4 4.4 0.017 14.2 1.7 2.4 1 1 0 1 1 1 1 Soluble NSF attachment protein, SNAP PPR PF01535.15 AIO02240.1 - 0.24 11.4 2.8 16 5.7 0.0 4.4 4 1 1 5 5 5 0 PPR repeat TPR_2 PF07719.12 AIO02240.1 - 0.27 11.2 10.7 13 6.0 0.2 5.7 7 0 0 7 7 5 0 Tetratricopeptide repeat TPR_19 PF14559.1 AIO02240.1 - 0.77 10.1 4.2 11 6.4 0.0 4.0 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_11 PF13414.1 AIO02240.1 - 0.78 9.4 6.4 30 4.3 0.1 4.4 3 1 1 4 4 4 0 TPR repeat TPR_1 PF00515.23 AIO02240.1 - 3.5 7.4 8.3 37 4.1 0.3 4.6 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_8 PF13181.1 AIO02240.1 - 3.8 7.5 8.7 1.2e+02 2.8 0.0 5.4 6 1 1 7 7 7 0 Tetratricopeptide repeat DUF2229 PF09989.4 AIO02241.1 - 0.27 10.6 1.1 1.4 8.3 0.1 2.1 2 0 0 2 2 2 0 CoA enzyme activase uncharacterised domain (DUF2229) LOH1CR12 PF10158.4 AIO02241.1 - 0.28 10.9 4.1 0.2 11.4 0.5 2.4 3 0 0 3 3 3 0 Tumour suppressor protein HTH_15 PF12324.3 AIO02243.1 - 0.081 12.5 0.7 29 4.4 0.0 3.6 3 0 0 3 3 3 0 Helix-turn-helix domain of alkylmercury lyase CLAMP PF14769.1 AIO02244.1 - 3.9e-30 103.9 0.9 7.7e-30 103.0 0.6 1.5 1 0 0 1 1 1 1 Flagellar C1a complex subunit C1a-32 DUF2317 PF10079.4 AIO02244.1 - 0.06 11.9 0.1 0.097 11.2 0.1 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2317) DUF1409 PF07197.7 AIO02244.1 - 0.075 13.1 0.4 0.19 11.7 0.2 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1409) MerR-DNA-bind PF09278.6 AIO02244.1 - 1.2 9.6 5.7 0.46 10.9 0.5 2.6 2 0 0 2 2 2 0 MerR, DNA binding Ribonuclease_3 PF00636.21 AIO02245.1 - 0.0028 18.0 0.0 0.014 15.8 0.0 2.1 1 1 0 1 1 1 1 Ribonuclease III domain Ribul_P_3_epim PF00834.14 AIO02245.1 - 0.11 11.5 0.0 0.3 10.1 0.0 1.6 2 0 0 2 2 2 0 Ribulose-phosphate 3 epimerase family WHIM2 PF15613.1 AIO02246.1 - 0.0017 18.2 0.0 0.0041 16.9 0.0 1.6 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 2 DDT PF02791.12 AIO02246.1 - 0.007 16.1 0.0 0.016 14.9 0.0 1.6 1 0 0 1 1 1 1 DDT domain Ribosomal_L24e PF01246.15 AIO02247.1 - 8e-15 54.4 0.5 8e-15 54.4 0.3 1.7 2 0 0 2 2 2 1 Ribosomal protein L24e XhoI PF04555.8 AIO02248.1 - 0.054 12.9 0.0 0.087 12.2 0.0 1.2 1 0 0 1 1 1 0 Restriction endonuclease XhoI DUF4189 PF13827.1 AIO02249.1 - 0.032 14.4 1.3 0.04 14.1 0.4 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4189) Ribosomal_L24e PF01246.15 AIO02250.1 - 8e-15 54.4 0.5 8e-15 54.4 0.3 1.7 2 0 0 2 2 2 1 Ribosomal protein L24e HORMA PF02301.13 AIO02251.1 - 4e-46 157.1 0.0 5.4e-46 156.6 0.0 1.2 1 0 0 1 1 1 1 HORMA domain MRP_L53 PF10780.4 AIO02251.1 - 0.14 12.1 0.3 0.75 9.8 0.0 2.3 2 0 0 2 2 2 0 39S ribosomal protein L53/MRP-L53 3HCDH_N PF02737.13 AIO02254.1 - 1.6e-56 190.8 1.9 2e-56 190.5 1.3 1.1 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.17 AIO02254.1 - 1.4e-34 118.3 0.0 1.1e-33 115.4 0.0 2.2 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain NAD_binding_2 PF03446.10 AIO02254.1 - 0.015 15.1 3.0 0.62 9.8 2.1 2.2 1 1 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Pyr_redox PF00070.22 AIO02254.1 - 0.032 14.6 0.1 0.073 13.4 0.1 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase F420_oxidored PF03807.12 AIO02254.1 - 0.13 12.6 1.3 0.52 10.7 0.9 2.0 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Exo_endo_phos PF03372.18 AIO02255.1 - 3.2e-09 37.0 0.0 2.1e-07 31.1 0.0 2.6 2 1 0 2 2 2 2 Endonuclease/Exonuclease/phosphatase family Memo PF01875.12 AIO02256.1 - 4.1e-62 209.5 0.0 5.6e-62 209.1 0.0 1.1 1 0 0 1 1 1 1 Memo-like protein CorA PF01544.13 AIO02257.1 - 4.3e-05 22.6 0.1 0.00022 20.3 0.1 2.0 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein Abhydrolase_9 PF10081.4 AIO02259.1 - 0.028 13.1 0.1 0.035 12.8 0.0 1.1 1 0 0 1 1 1 0 Alpha/beta-hydrolase family CaM_bdg_C0 PF10562.4 AIO02259.1 - 0.15 11.9 0.9 0.28 11.0 0.2 1.8 2 0 0 2 2 2 0 Calmodulin-binding domain C0 of NMDA receptor NR1 subunit Glyco_transf_22 PF03901.12 AIO02260.1 - 4.6e-70 236.7 22.7 5.8e-70 236.3 15.7 1.1 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family PilX_N PF14341.1 AIO02260.1 - 0.9 9.2 5.8 0.18 11.4 0.5 2.4 2 0 0 2 2 2 0 PilX N-terminal PP2C PF00481.16 AIO02263.1 - 1.7e-10 40.7 0.0 3.5e-10 39.7 0.0 1.6 1 0 0 1 1 1 1 Protein phosphatase 2C DUF2567 PF10821.3 AIO02265.1 - 0.2 11.1 2.1 1.5 8.3 0.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2567) Ribosomal_S4 PF00163.14 AIO02266.1 - 7.4e-29 99.9 0.4 1.5e-28 99.0 0.3 1.5 1 0 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain S4 PF01479.20 AIO02266.1 - 5.9e-14 51.2 0.4 1.3e-13 50.1 0.3 1.6 1 0 0 1 1 1 1 S4 domain Glycolytic PF00274.14 AIO02267.1 - 2.3e-144 480.0 0.0 2.6e-144 479.9 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-I PSD4 PF07631.6 AIO02268.1 - 0.022 15.1 1.9 4.6 7.6 0.1 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF1592) DUF3094 PF11293.3 AIO02268.1 - 5.3 6.6 7.4 1.6 8.2 0.3 3.0 4 0 0 4 4 4 0 Protein of unknown function (DUF3094) SIP1 PF04938.7 AIO02269.1 - 0.00095 18.5 0.0 0.0027 17.1 0.0 1.8 2 0 0 2 2 2 1 Survival motor neuron (SMN) interacting protein 1 (SIP1) CENP-F_leu_zip PF10473.4 AIO02270.1 - 0.00092 19.0 12.0 0.0031 17.3 7.1 2.0 2 0 0 2 2 2 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 CAF-1_p150 PF11600.3 AIO02270.1 - 0.0024 17.2 11.1 0.0034 16.7 7.7 1.1 1 0 0 1 1 1 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal DUF4192 PF13830.1 AIO02270.1 - 0.018 14.6 9.0 0.031 13.9 6.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4192) APG6 PF04111.7 AIO02270.1 - 0.02 13.9 5.7 0.034 13.2 4.0 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF3035 PF11233.3 AIO02270.1 - 0.16 11.9 6.4 0.2 11.7 4.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3035) OmpH PF03938.9 AIO02270.1 - 0.49 10.3 3.5 0.85 9.5 2.4 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) GAS PF13851.1 AIO02270.1 - 1.3 8.1 10.0 2.4 7.3 6.9 1.3 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding ADIP PF11559.3 AIO02270.1 - 3.4 7.5 12.0 11 5.9 7.7 1.9 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding CorA PF01544.13 AIO02270.1 - 4.9 6.1 7.0 8.6 5.2 4.8 1.3 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein AphA_like PF14557.1 AIO02271.1 - 0.017 14.6 0.4 0.033 13.7 0.3 1.4 1 0 0 1 1 1 0 Putative AphA-like transcriptional regulator SlyX PF04102.7 AIO02271.1 - 1.2 9.5 4.5 1.2 9.5 1.6 2.0 1 1 1 2 2 2 0 SlyX DnaJ PF00226.26 AIO02272.1 - 1.3e-08 34.4 0.0 2.1e-08 33.7 0.0 1.3 1 0 0 1 1 1 1 DnaJ domain DUF1007 PF06226.8 AIO02272.1 - 0.072 12.8 0.0 0.12 12.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1007) NARP1 PF12569.3 AIO02273.1 - 2.7e-85 287.1 14.1 5.5e-82 276.1 5.2 2.9 3 1 1 4 4 4 2 NMDA receptor-regulated protein 1 TPR_11 PF13414.1 AIO02273.1 - 6.3e-22 77.0 15.8 3.4e-06 26.6 0.0 6.5 6 0 0 6 6 6 4 TPR repeat TPR_2 PF07719.12 AIO02273.1 - 6.8e-18 63.0 17.3 4e-05 23.2 0.0 8.9 9 0 0 9 9 7 4 Tetratricopeptide repeat TPR_19 PF14559.1 AIO02273.1 - 8.5e-13 48.4 19.2 0.0022 18.2 0.0 6.7 6 1 2 8 8 7 3 Tetratricopeptide repeat TPR_14 PF13428.1 AIO02273.1 - 1.6e-12 46.8 23.0 0.011 16.2 0.1 9.0 8 2 2 10 10 9 4 Tetratricopeptide repeat TPR_1 PF00515.23 AIO02273.1 - 3e-11 42.4 14.6 6.8e-06 25.4 0.0 7.3 8 0 0 8 8 7 3 Tetratricopeptide repeat TPR_17 PF13431.1 AIO02273.1 - 4e-10 39.0 2.9 0.36 11.1 0.0 6.4 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_16 PF13432.1 AIO02273.1 - 6.9e-10 39.3 29.3 0.0034 18.0 0.0 8.3 9 1 1 10 10 8 2 Tetratricopeptide repeat TPR_8 PF13181.1 AIO02273.1 - 1e-09 37.4 1.2 0.2 11.5 0.0 6.6 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_9 PF13371.1 AIO02273.1 - 1.8e-08 34.1 12.4 0.00022 21.0 0.0 5.3 5 1 1 6 6 6 2 Tetratricopeptide repeat TPR_12 PF13424.1 AIO02273.1 - 5.1e-07 29.5 18.8 0.012 15.5 1.6 6.3 5 2 1 6 6 6 2 Tetratricopeptide repeat TPR_7 PF13176.1 AIO02273.1 - 0.00016 21.2 13.4 2.6 8.0 0.0 7.0 8 0 0 8 8 7 3 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 AIO02273.1 - 0.00097 18.9 1.5 7.3 6.5 0.0 5.0 5 0 0 5 5 5 1 Fis1 C-terminal tetratricopeptide repeat DUF1771 PF08590.5 AIO02273.1 - 1.5 8.8 15.5 0.1 12.5 1.8 3.8 3 1 1 4 4 4 0 Domain of unknown function (DUF1771) zf-PARP PF00645.13 AIO02274.1 - 9.2e-23 80.2 2.1 1.9e-22 79.3 1.5 1.5 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region zf-CCHH PF10283.4 AIO02274.1 - 8.2e-12 44.7 5.1 1.4e-11 44.0 3.6 1.3 1 0 0 1 1 1 1 Zinc-finger (CX5CX6HX5H) motif ADK PF00406.17 AIO02275.1 - 1.7e-41 141.5 0.0 3.5e-41 140.5 0.0 1.5 1 1 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.1 AIO02275.1 - 8.4e-11 42.7 0.0 2.2e-10 41.3 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 AIO02275.1 - 1.8e-09 38.0 0.1 1.2e-08 35.2 0.0 2.1 2 1 0 2 2 2 1 AAA domain AAA_33 PF13671.1 AIO02275.1 - 4.5e-05 23.3 0.6 0.00031 20.6 0.0 2.6 1 1 0 2 2 2 1 AAA domain ADK_lid PF05191.9 AIO02275.1 - 0.00016 21.2 0.0 0.00034 20.2 0.0 1.6 1 0 0 1 1 1 1 Adenylate kinase, active site lid Zeta_toxin PF06414.7 AIO02275.1 - 0.0079 15.3 0.2 0.033 13.2 0.0 1.9 2 0 0 2 2 2 1 Zeta toxin KTI12 PF08433.5 AIO02275.1 - 0.057 12.6 0.0 0.1 11.7 0.0 1.4 1 0 0 1 1 1 0 Chromatin associated protein KTI12 Thymidylate_kin PF02223.12 AIO02275.1 - 0.06 12.7 0.2 11 5.2 0.0 2.6 3 0 0 3 3 3 0 Thymidylate kinase AAA_5 PF07728.9 AIO02275.1 - 0.081 12.6 0.1 2.5 7.8 0.0 2.3 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_28 PF13521.1 AIO02275.1 - 0.11 12.4 0.0 0.23 11.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA PF00004.24 AIO02276.1 - 2.5e-95 315.6 0.0 3.2e-46 156.7 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) CDC48_N PF02359.13 AIO02276.1 - 6.8e-21 74.0 0.2 2.9e-20 71.9 0.1 2.2 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), N-terminal domain AAA_17 PF13207.1 AIO02276.1 - 1.2e-13 51.8 0.1 4.1e-05 24.4 0.0 3.8 3 1 0 3 3 3 2 AAA domain RuvB_N PF05496.7 AIO02276.1 - 1.6e-13 50.2 0.0 9e-06 24.8 0.0 2.8 2 1 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 AIO02276.1 - 2.5e-13 50.4 0.0 8.3e-06 25.8 0.0 3.1 2 1 1 3 3 3 2 AAA ATPase domain AAA_33 PF13671.1 AIO02276.1 - 3.6e-12 46.3 0.0 4.1e-06 26.7 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_2 PF07724.9 AIO02276.1 - 5.6e-12 45.8 0.0 2.7e-06 27.4 0.0 2.7 2 1 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_22 PF13401.1 AIO02276.1 - 7.3e-12 45.5 0.3 0.00025 21.2 0.1 4.1 2 2 0 2 2 2 2 AAA domain AAA_5 PF07728.9 AIO02276.1 - 6.6e-11 42.0 0.3 4.4e-05 23.2 0.0 3.7 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) CDC48_2 PF02933.12 AIO02276.1 - 2.4e-09 36.6 0.0 5.4e-09 35.5 0.0 1.6 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), domain 2 Zeta_toxin PF06414.7 AIO02276.1 - 3.5e-09 36.0 0.0 0.0018 17.3 0.0 2.5 2 0 0 2 2 2 2 Zeta toxin AAA_14 PF13173.1 AIO02276.1 - 4.3e-09 36.3 0.0 0.00097 19.0 0.0 2.5 2 0 0 2 2 2 2 AAA domain TIP49 PF06068.8 AIO02276.1 - 9.3e-09 34.4 0.0 0.00029 19.6 0.0 2.4 2 0 0 2 2 2 2 TIP49 C-terminus AAA_18 PF13238.1 AIO02276.1 - 1.1e-07 32.2 0.0 0.0079 16.4 0.0 2.8 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.17 AIO02276.1 - 1.9e-07 31.1 0.0 0.0047 17.0 0.0 3.0 2 0 0 2 2 2 2 RNA helicase IstB_IS21 PF01695.12 AIO02276.1 - 2.6e-07 30.2 0.0 0.012 15.0 0.0 2.5 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_25 PF13481.1 AIO02276.1 - 2.9e-07 30.1 3.6 0.028 13.8 0.1 4.0 2 2 0 3 3 3 1 AAA domain Mg_chelatase PF01078.16 AIO02276.1 - 4.3e-07 29.2 0.2 0.027 13.6 0.0 2.6 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI Arch_ATPase PF01637.13 AIO02276.1 - 1.2e-06 28.4 0.1 1 9.0 0.0 3.4 2 1 1 3 3 3 3 Archaeal ATPase AAA_19 PF13245.1 AIO02276.1 - 1.6e-06 27.7 1.7 0.035 13.8 0.2 2.9 3 0 0 3 3 2 2 Part of AAA domain AAA_28 PF13521.1 AIO02276.1 - 4.8e-06 26.6 0.0 0.17 11.8 0.0 2.9 3 0 0 3 3 2 2 AAA domain ResIII PF04851.10 AIO02276.1 - 6.2e-06 26.1 0.0 0.0018 18.1 0.0 2.3 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit NACHT PF05729.7 AIO02276.1 - 8e-06 25.6 0.1 0.15 11.6 0.0 3.6 3 1 1 4 4 3 2 NACHT domain ABC_tran PF00005.22 AIO02276.1 - 1.1e-05 25.7 0.0 0.045 14.0 0.0 3.1 2 1 0 2 2 2 1 ABC transporter Sigma54_activ_2 PF14532.1 AIO02276.1 - 1.3e-05 25.3 0.0 0.03 14.3 0.0 2.4 2 0 0 2 2 2 2 Sigma-54 interaction domain Parvo_NS1 PF01057.12 AIO02276.1 - 3e-05 23.0 0.0 0.046 12.5 0.0 2.2 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 KaiC PF06745.8 AIO02276.1 - 5.1e-05 22.5 1.7 1.3 8.0 0.0 3.6 2 1 1 3 3 3 1 KaiC Vps4_C PF09336.5 AIO02276.1 - 5.3e-05 23.0 0.0 0.0007 19.4 0.0 2.5 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain Sigma54_activat PF00158.21 AIO02276.1 - 6.1e-05 22.5 0.1 0.41 10.0 0.0 3.3 2 1 0 2 2 2 2 Sigma-54 interaction domain AAA_24 PF13479.1 AIO02276.1 - 7e-05 22.5 0.0 0.34 10.4 0.0 2.6 2 0 0 2 2 2 2 AAA domain NTPase_1 PF03266.10 AIO02276.1 - 0.0001 22.0 1.3 2.6 7.7 0.0 4.3 3 1 1 4 4 4 1 NTPase Viral_helicase1 PF01443.13 AIO02276.1 - 0.00018 21.1 0.0 0.012 15.1 0.0 2.3 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase NB-ARC PF00931.17 AIO02276.1 - 0.00026 19.9 0.1 0.58 8.9 0.0 2.3 2 0 0 2 2 2 2 NB-ARC domain AAA_3 PF07726.6 AIO02276.1 - 0.00029 20.4 0.0 1.1 8.9 0.0 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) Bac_DnaA PF00308.13 AIO02276.1 - 0.00038 20.1 0.0 0.61 9.6 0.0 2.6 2 0 0 2 2 2 1 Bacterial dnaA protein PhoH PF02562.11 AIO02276.1 - 0.0012 18.1 0.2 0.71 9.0 0.0 2.5 2 0 0 2 2 2 1 PhoH-like protein DUF2075 PF09848.4 AIO02276.1 - 0.003 16.5 0.0 0.99 8.3 0.0 2.4 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) Cytidylate_kin2 PF13189.1 AIO02276.1 - 0.0031 17.4 0.0 0.32 10.8 0.0 2.5 2 0 0 2 2 2 1 Cytidylate kinase-like family SKI PF01202.17 AIO02276.1 - 0.0038 17.1 0.0 3.2 7.5 0.0 2.6 2 0 0 2 2 2 0 Shikimate kinase AAA_23 PF13476.1 AIO02276.1 - 0.0062 16.8 0.0 5.6 7.2 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_10 PF12846.2 AIO02276.1 - 0.0071 15.8 0.2 4.2 6.7 0.0 3.6 3 1 1 4 4 4 0 AAA-like domain DUF815 PF05673.8 AIO02276.1 - 0.0077 15.1 0.0 3.3 6.5 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF815) Molydop_binding PF01568.16 AIO02276.1 - 0.009 15.8 0.0 0.025 14.3 0.0 1.7 1 0 0 1 1 1 1 Molydopterin dinucleotide binding domain UPF0079 PF02367.12 AIO02276.1 - 0.011 15.3 0.4 6.4 6.4 0.0 2.8 3 0 0 3 3 2 0 Uncharacterised P-loop hydrolase UPF0079 T2SE PF00437.15 AIO02276.1 - 0.016 14.1 0.0 7.5 5.3 0.0 3.2 3 0 0 3 3 3 0 Type II/IV secretion system protein DEAD PF00270.24 AIO02276.1 - 0.019 14.4 0.4 7.8 5.9 0.0 3.4 3 1 1 4 4 3 0 DEAD/DEAH box helicase TEX19 PF15553.1 AIO02276.1 - 0.031 14.1 0.1 0.056 13.3 0.1 1.4 1 0 0 1 1 1 0 Testis-expressed protein 19 AAA_21 PF13304.1 AIO02276.1 - 0.043 13.7 0.6 14 5.5 0.4 3.1 2 1 0 2 2 2 0 AAA domain KTI12 PF08433.5 AIO02276.1 - 0.047 12.8 0.1 8.7 5.4 0.0 2.6 2 1 0 2 2 2 0 Chromatin associated protein KTI12 Zot PF05707.7 AIO02276.1 - 0.051 13.0 0.4 4.7 6.6 0.2 3.3 2 1 0 2 2 2 0 Zonular occludens toxin (Zot) AAA_11 PF13086.1 AIO02276.1 - 0.052 13.1 0.0 4.2 6.8 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.1 AIO02276.1 - 0.053 13.0 0.0 8.9 5.9 0.0 2.6 2 0 0 2 2 2 0 P-loop containing region of AAA domain eIF-1a PF01176.14 AIO02276.1 - 0.084 12.2 0.8 1.1 8.7 0.0 2.5 2 0 0 2 2 2 0 Translation initiation factor 1A / IF-1 KAP_NTPase PF07693.9 AIO02276.1 - 0.1 11.5 0.0 6 5.7 0.0 3.0 2 1 1 3 3 3 0 KAP family P-loop domain ATP-synt_ab PF00006.20 AIO02276.1 - 0.12 11.8 0.0 3.4 7.1 0.0 2.5 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain DAP3 PF10236.4 AIO02276.1 - 0.22 10.4 0.0 17 4.2 0.0 2.4 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 Aa_trans PF01490.13 AIO02277.1 - 1.4e-40 139.0 24.3 1.7e-40 138.7 16.8 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trypsin_2 PF13365.1 AIO02278.1 - 3.6e-05 23.7 0.0 6.2e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 Trypsin-like peptidase domain zf-Dof PF02701.10 AIO02279.1 - 0.098 12.5 1.0 0.22 11.4 0.7 1.6 1 0 0 1 1 1 0 Dof domain, zinc finger Nop16 PF09420.5 AIO02279.1 - 1.1 9.3 7.7 2.7 8.0 0.0 4.1 5 0 0 5 5 5 0 Ribosome biogenesis protein Nop16 ARL2_Bind_BART PF11527.3 AIO02280.1 - 6.1e-37 126.1 0.1 6.1e-37 126.1 0.1 2.1 2 0 0 2 2 2 1 The ARF-like 2 binding protein BART UIM PF02809.15 AIO02280.1 - 0.0016 17.8 1.4 0.0016 17.8 1.0 2.3 2 0 0 2 2 2 1 Ubiquitin interaction motif DZR PF12773.2 AIO02281.1 - 2.8e-06 27.0 137.3 0.00018 21.2 6.5 10.9 8 3 3 11 11 11 9 Double zinc ribbon zf-RanBP PF00641.13 AIO02281.1 - 0.0052 15.8 5.0 0.0052 15.8 3.5 15.5 13 2 1 14 14 14 6 Zn-finger in Ran binding protein and others zf-RanBP PF00641.13 AIO02282.1 - 9.4e-21 72.6 85.3 6.1e-08 31.6 2.0 9.7 10 0 0 10 10 10 8 Zn-finger in Ran binding protein and others DZR PF12773.2 AIO02282.1 - 1e-08 34.8 63.2 0.01 15.6 3.3 6.7 4 3 2 6 6 6 6 Double zinc ribbon Ca_hom_mod PF14798.1 AIO02282.1 - 0.034 13.0 3.9 0.076 11.9 2.7 1.5 1 0 0 1 1 1 0 Calcium homeostasis modulator EF1_GNE PF00736.14 AIO02283.1 - 1.2e-29 101.8 2.1 2e-29 101.0 1.4 1.4 1 0 0 1 1 1 1 EF-1 guanine nucleotide exchange domain Mrr_cat PF04471.7 AIO02283.1 - 0.012 15.4 1.1 0.59 9.9 0.3 2.9 1 1 2 3 3 3 0 Restriction endonuclease Chorein_N PF12624.2 AIO02284.1 - 2.6e-23 81.7 0.1 8.2e-12 44.7 0.0 2.8 2 0 0 2 2 2 2 N-terminal region of Chorein, a TM vesicle-mediated sorter DUF3419 PF11899.3 AIO02285.1 - 0.014 14.1 0.0 0.017 13.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3419) Kelch_1 PF01344.20 AIO02287.1 - 4.3e-12 45.3 1.0 1.8e-05 24.1 0.0 3.5 3 0 0 3 3 3 2 Kelch motif Kelch_3 PF13415.1 AIO02287.1 - 4.7e-11 42.5 5.3 2e-05 24.6 0.0 5.2 5 0 0 5 5 5 2 Galactose oxidase, central domain Kelch_4 PF13418.1 AIO02287.1 - 7.9e-11 41.5 3.1 0.00026 20.6 0.0 5.2 4 1 1 5 5 5 3 Galactose oxidase, central domain Kelch_6 PF13964.1 AIO02287.1 - 4.4e-10 39.2 3.3 0.0036 17.4 0.0 5.2 7 0 0 7 7 7 3 Kelch motif Kelch_5 PF13854.1 AIO02287.1 - 6.9e-08 32.2 2.1 0.0079 16.1 0.0 4.1 4 0 0 4 4 4 2 Kelch motif Kelch_2 PF07646.10 AIO02287.1 - 1e-07 31.4 0.1 0.02 14.6 0.0 4.5 4 0 0 4 4 4 2 Kelch motif PilJ PF13675.1 AIO02291.1 - 0.0036 17.6 0.7 0.0046 17.2 0.5 1.3 1 0 0 1 1 1 1 Type IV pili methyl-accepting chemotaxis transducer N-term DUF1156 PF06634.7 AIO02291.1 - 0.03 14.0 0.0 0.059 13.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1156) Fib_alpha PF08702.5 AIO02291.1 - 0.058 13.5 0.9 0.076 13.1 0.6 1.2 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family P4Ha_N PF08336.6 AIO02291.1 - 0.075 12.8 0.4 0.14 11.9 0.2 1.4 1 1 0 1 1 1 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region DUF4363 PF14276.1 AIO02291.1 - 0.14 11.8 0.3 0.29 10.8 0.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4363) Laminin_II PF06009.7 AIO02291.1 - 0.16 11.7 3.7 0.76 9.5 0.2 2.1 2 0 0 2 2 2 0 Laminin Domain II TBPIP PF07106.8 AIO02291.1 - 0.22 11.0 1.5 0.3 10.6 1.1 1.1 1 0 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Snf7 PF03357.16 AIO02291.1 - 0.51 9.6 5.2 0.3 10.4 0.7 2.0 1 1 1 2 2 2 0 Snf7 Syntaxin-6_N PF09177.6 AIO02291.1 - 0.87 10.0 4.7 7.1 7.1 1.1 2.2 1 1 1 2 2 2 0 Syntaxin 6, N-terminal Pkinase PF00069.20 AIO02292.1 - 3.3e-55 187.0 0.0 4.7e-55 186.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AIO02292.1 - 1.3e-35 122.7 0.0 2e-35 122.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 AIO02292.1 - 2.4e-06 26.7 0.0 5.4e-06 25.5 0.0 1.4 1 1 0 1 1 1 1 Kinase-like PH PF00169.24 AIO02292.1 - 8.6e-05 22.6 0.1 0.00018 21.6 0.1 1.6 1 1 0 1 1 1 1 PH domain PH_9 PF15410.1 AIO02292.1 - 0.045 13.9 0.1 0.15 12.2 0.1 1.9 1 1 0 1 1 1 0 Pleckstrin homology domain PH_4 PF15404.1 AIO02292.1 - 0.053 13.0 0.1 0.12 11.9 0.0 1.5 1 0 0 1 1 1 0 Pleckstrin homology domain PH_2 PF08458.5 AIO02292.1 - 0.056 13.3 0.0 0.14 12.0 0.0 1.7 1 0 0 1 1 1 0 Plant pleckstrin homology-like region PH_11 PF15413.1 AIO02292.1 - 0.11 12.6 0.1 0.32 11.2 0.1 1.8 1 1 0 1 1 1 0 Pleckstrin homology domain Pkinase PF00069.20 AIO02293.1 - 7.9e-52 175.9 0.0 1.2e-51 175.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AIO02293.1 - 2.5e-35 121.8 0.0 4.7e-35 120.9 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 AIO02293.1 - 1.1e-07 31.1 0.0 1.8e-07 30.4 0.0 1.3 1 0 0 1 1 1 1 Kinase-like PH PF00169.24 AIO02293.1 - 7.8e-07 29.2 0.1 7.6e-06 26.0 0.1 2.2 1 1 0 1 1 1 1 PH domain PH_9 PF15410.1 AIO02293.1 - 0.027 14.6 0.0 0.069 13.3 0.0 1.7 1 0 0 1 1 1 0 Pleckstrin homology domain ELMO_CED12 PF04727.8 AIO02294.1 - 5.9e-39 133.3 0.0 8.3e-39 132.8 0.0 1.2 1 0 0 1 1 1 1 ELMO/CED-12 family zf-B_box PF00643.19 AIO02295.1 - 8.5e-08 31.9 26.3 1.1e-07 31.5 5.7 3.8 4 0 0 4 4 4 2 B-box zinc finger Baculo_PEP_C PF04513.7 AIO02295.1 - 0.00021 21.1 0.0 0.00036 20.3 0.0 1.3 1 0 0 1 1 1 1 Baculovirus polyhedron envelope protein, PEP, C terminus Spectrin PF00435.16 AIO02295.1 - 0.11 12.7 0.8 0.28 11.4 0.5 1.7 1 0 0 1 1 1 0 Spectrin repeat LRR_4 PF12799.2 AIO02296.1 - 6.1e-18 64.0 3.0 0.00045 19.7 0.0 5.6 5 1 1 6 6 6 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 AIO02296.1 - 5.3e-12 45.3 9.3 1.5e-05 24.6 0.1 4.4 2 1 3 5 5 5 4 Leucine rich repeat LRR_1 PF00560.28 AIO02296.1 - 2.2e-05 23.8 14.0 5.9 7.3 0.3 8.2 7 2 0 7 7 7 1 Leucine Rich Repeat LRR_5 PF13306.1 AIO02296.1 - 0.00061 19.4 0.0 0.0011 18.7 0.0 1.3 1 0 0 1 1 1 1 Leucine rich repeats (6 copies) LRR_6 PF13516.1 AIO02296.1 - 0.00097 18.9 8.1 64 4.0 0.1 6.7 8 0 0 8 8 8 0 Leucine Rich repeat LRR_7 PF13504.1 AIO02296.1 - 0.16 12.3 23.0 7.9 7.1 0.1 7.7 8 0 0 8 8 8 0 Leucine rich repeat Protocadherin PF08374.6 AIO02297.1 - 0.00025 20.7 0.1 0.00048 19.8 0.1 1.4 1 0 0 1 1 1 1 Protocadherin DUF743 PF05332.6 AIO02297.1 - 0.11 12.4 3.4 0.068 13.1 0.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF743) STAG PF08514.6 AIO02299.1 - 6.9e-18 64.4 0.2 2.3e-17 62.8 0.2 1.9 1 0 0 1 1 1 1 STAG domain DUF2435 PF10363.4 AIO02299.1 - 0.012 15.5 0.7 10 6.0 0.0 4.4 3 1 1 4 4 4 0 Protein of unknown function (DUF2435) Proteasome PF00227.21 AIO02301.1 - 1.2e-56 190.9 0.0 1.5e-56 190.6 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 AIO02301.1 - 2.8e-13 48.9 0.0 8.7e-13 47.3 0.0 1.9 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature CRISPR_Cse2 PF09485.5 AIO02301.1 - 0.11 12.5 0.0 0.21 11.6 0.0 1.4 1 0 0 1 1 1 0 CRISPR-associated protein Cse2 (CRISPR_cse2) zf-CCHC PF00098.18 AIO02302.1 - 3.7e-42 140.2 34.0 1.3e-09 37.4 1.3 5.1 5 0 0 5 5 5 5 Zinc knuckle zf-CCHC_4 PF14392.1 AIO02302.1 - 1.5e-13 50.1 31.7 0.00073 19.1 0.8 5.0 5 0 0 5 5 5 5 Zinc knuckle zf-CCHC_3 PF13917.1 AIO02302.1 - 7.6e-12 44.7 27.0 0.019 14.6 0.7 5.0 1 1 4 5 5 5 5 Zinc knuckle zf-CCHC_2 PF13696.1 AIO02302.1 - 3.1e-08 32.9 16.8 0.0046 16.4 0.1 4.9 2 2 3 5 5 5 3 Zinc knuckle zf-CCHC_6 PF15288.1 AIO02302.1 - 0.00034 20.2 30.2 0.1 12.2 0.9 5.1 2 2 3 5 5 5 3 Zinc knuckle RMF PF04957.7 AIO02302.1 - 3 7.6 7.6 18 5.0 0.1 3.3 2 2 1 3 3 3 0 Ribosome modulation factor TNFR_c6 PF00020.13 AIO02302.1 - 5.7 7.0 33.7 6.4 6.9 0.9 5.0 2 2 3 5 5 5 0 TNFR/NGFR cysteine-rich region zf-CCHC PF00098.18 AIO02303.1 - 4.5e-42 140.0 35.4 1.3e-09 37.4 1.3 5.1 5 0 0 5 5 5 5 Zinc knuckle zf-CCHC_4 PF14392.1 AIO02303.1 - 1.3e-13 50.3 31.8 0.00073 19.1 0.8 5.0 5 0 0 5 5 5 5 Zinc knuckle zf-CCHC_3 PF13917.1 AIO02303.1 - 3.8e-12 45.7 27.3 0.015 14.9 0.3 5.0 1 1 4 5 5 5 5 Zinc knuckle zf-CCHC_2 PF13696.1 AIO02303.1 - 9.9e-08 31.3 17.1 0.0046 16.4 0.1 4.9 2 2 3 5 5 5 3 Zinc knuckle zf-CCHC_6 PF15288.1 AIO02303.1 - 0.00012 21.6 31.4 0.025 14.2 1.2 5.1 2 2 3 5 5 5 3 Zinc knuckle RMF PF04957.7 AIO02303.1 - 1.9 8.2 7.8 18 5.0 0.1 3.3 2 2 1 3 3 3 0 Ribosome modulation factor TNFR_c6 PF00020.13 AIO02303.1 - 5.1 7.2 33.9 6.4 6.9 0.9 5.0 2 2 3 5 5 5 0 TNFR/NGFR cysteine-rich region Toxin_44 PF15523.1 AIO02303.1 - 5.5 6.9 18.6 4.1 7.3 0.1 3.6 1 1 2 3 3 3 0 Putative toxin 44 Clathrin PF00637.15 AIO02304.1 - 7.3e-162 531.4 43.0 1.1e-26 93.1 1.8 8.3 8 0 0 8 8 8 8 Region in Clathrin and VPS Clathrin_H_link PF13838.1 AIO02304.1 - 8.5e-22 76.8 2.5 3.4e-21 74.9 0.0 3.2 4 0 0 4 4 4 1 Clathrin-H-link Clathrin_propel PF01394.15 AIO02304.1 - 1.1e-11 44.1 0.4 3 8.3 0.0 6.9 6 0 0 6 6 6 3 Clathrin propeller repeat Clathrin-link PF09268.5 AIO02304.1 - 5.5e-11 41.2 0.1 1.6e-10 39.8 0.1 1.9 1 0 0 1 1 1 1 Clathrin, heavy-chain linker ACDC PF14733.1 AIO02304.1 - 0.00085 19.3 0.6 1.6 8.8 0.0 4.1 4 0 0 4 4 4 1 AP2-coincident C-terminal TPR_7 PF13176.1 AIO02304.1 - 0.02 14.6 2.2 39 4.3 0.0 5.7 5 0 0 5 5 5 0 Tetratricopeptide repeat DUF1626 PF07788.6 AIO02304.1 - 0.038 13.7 0.5 1.2 8.9 0.0 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1626) TPR_1 PF00515.23 AIO02304.1 - 0.058 13.0 5.7 14 5.4 0.1 5.4 5 0 0 5 5 5 0 Tetratricopeptide repeat CAF1 PF04857.15 AIO02304.1 - 0.11 11.7 0.1 0.18 11.1 0.0 1.3 1 0 0 1 1 1 0 CAF1 family ribonuclease zf-CCHC PF00098.18 AIO02305.1 - 1.4e-38 129.0 48.2 2.1e-07 30.5 0.4 6.1 6 0 0 6 6 6 6 Zinc knuckle zf-CCHC_2 PF13696.1 AIO02305.1 - 6.3e-09 35.1 29.8 0.0011 18.4 0.4 5.8 4 1 2 6 6 6 4 Zinc knuckle zf-CCHC_3 PF13917.1 AIO02305.1 - 3.3e-08 33.1 32.8 0.0074 16.0 0.7 5.4 2 1 3 5 5 5 4 Zinc knuckle zf-CCHC_4 PF14392.1 AIO02305.1 - 3.6e-07 29.7 37.5 0.097 12.3 0.5 6.0 6 0 0 6 6 6 5 Zinc knuckle zf-CCHC_5 PF14787.1 AIO02305.1 - 0.0013 18.1 38.7 0.022 14.2 0.4 5.5 5 1 1 6 6 6 4 GAG-polyprotein viral zinc-finger zf-CCHC PF00098.18 AIO02306.1 - 3.3e-69 225.7 72.5 4e-09 35.9 2.4 8.2 8 0 0 8 8 8 8 Zinc knuckle zf-CCHC_3 PF13917.1 AIO02306.1 - 3.7e-25 87.3 44.8 0.0007 19.2 0.3 8.1 5 1 3 8 8 8 8 Zinc knuckle zf-CCHC_2 PF13696.1 AIO02306.1 - 1.7e-11 43.3 40.1 0.097 12.1 0.3 8.2 8 0 0 8 8 8 8 Zinc knuckle zf-CCHC_4 PF14392.1 AIO02306.1 - 1.8e-10 40.3 55.7 0.24 11.0 0.6 8.1 8 0 0 8 8 8 8 Zinc knuckle eIF3g PF12353.3 AIO02306.1 - 0.0036 17.2 38.4 0.015 15.2 0.4 7.8 5 1 3 8 8 8 4 Eukaryotic translation initiation factor 3 subunit G zf-CCHC_5 PF14787.1 AIO02306.1 - 0.87 9.1 58.0 0.61 9.6 1.2 8.1 8 0 0 8 8 8 0 GAG-polyprotein viral zinc-finger IBR PF01485.16 AIO02306.1 - 2.4 8.1 46.6 6.6 6.6 0.4 8.0 8 0 0 8 8 8 0 IBR domain zf-CCHC_6 PF15288.1 AIO02306.1 - 3.9 7.2 64.1 2.1 8.0 1.6 8.2 7 1 1 8 8 8 0 Zinc knuckle Perm-CXXC PF15629.1 AIO02306.1 - 6.5 6.8 13.0 1.3e+02 2.6 0.2 6.2 6 0 0 6 6 6 0 Permuted single zf-CXXC unit Proteasome PF00227.21 AIO02307.1 - 4.8e-50 169.4 0.2 5.8e-50 169.2 0.2 1.1 1 0 0 1 1 1 1 Proteasome subunit S4 PF01479.20 AIO02308.1 - 2.6e-07 29.9 0.0 3e-06 26.5 0.0 2.4 2 0 0 2 2 2 1 S4 domain PseudoU_synth_2 PF00849.17 AIO02308.1 - 2.5e-05 24.1 0.0 4.4e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 RNA pseudouridylate synthase DUF2419 PF10343.4 AIO02309.1 - 4.3e-16 59.0 0.0 4.5e-13 49.0 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF2419) Peptidase_M76 PF09768.4 AIO02311.1 - 2.9e-53 179.8 0.0 8.8e-51 171.7 0.0 2.1 1 1 0 1 1 1 1 Peptidase M76 family HTH_30 PF13556.1 AIO02311.1 - 0.19 11.3 0.3 0.4 10.3 0.0 1.7 2 0 0 2 2 2 0 PucR C-terminal helix-turn-helix domain Dmrt1 PF12374.3 AIO02311.1 - 2.1 8.7 7.3 0.12 12.7 1.0 1.9 2 0 0 2 2 2 0 Double-sex mab3 related transcription factor 1 GPI2 PF06432.6 AIO02313.1 - 6.3e-79 265.2 14.2 7.4e-79 265.0 9.8 1.1 1 0 0 1 1 1 1 Phosphatidylinositol N-acetylglucosaminyltransferase DUF3149 PF11346.3 AIO02313.1 - 0.64 9.6 4.5 1.3 8.5 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3149) DUF778 PF05608.7 AIO02313.1 - 1 9.2 3.7 3.3 7.6 2.5 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF778) DUF1634 PF07843.6 AIO02313.1 - 1.8 8.2 9.2 0.21 11.2 0.2 3.3 2 2 0 3 3 3 0 Protein of unknown function (DUF1634) Beach PF02138.13 AIO02314.1 - 3.8e-99 331.5 0.0 5.4e-99 331.0 0.0 1.2 1 0 0 1 1 1 1 Beige/BEACH domain PH_BEACH PF14844.1 AIO02314.1 - 3.5e-21 75.0 0.0 7.2e-21 74.0 0.0 1.6 1 0 0 1 1 1 1 PH domain associated with Beige/BEACH WD40 PF00400.27 AIO02314.1 - 0.00015 21.5 0.1 1 9.3 0.0 3.6 3 0 0 3 3 3 2 WD domain, G-beta repeat Sec34 PF04136.10 AIO02315.1 - 1.4e-05 24.8 1.5 2.6e-05 23.9 0.2 1.9 2 0 0 2 2 2 1 Sec34-like family Thioredoxin_4 PF13462.1 AIO02316.1 - 0.22 11.4 0.0 0.54 10.2 0.0 1.5 1 0 0 1 1 1 0 Thioredoxin Lactonase PF10282.4 AIO02317.1 - 0.013 14.6 0.1 0.034 13.2 0.0 1.8 2 0 0 2 2 2 0 Lactonase, 7-bladed beta-propeller Aldedh PF00171.17 AIO02318.1 - 1e-164 548.2 0.1 1.2e-164 548.0 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family TPR_11 PF13414.1 AIO02320.1 - 4.9e-34 115.7 2.4 2.3e-09 36.7 0.1 5.9 4 2 0 5 5 5 5 TPR repeat TPR_2 PF07719.12 AIO02320.1 - 8e-14 50.3 12.0 0.022 14.6 0.0 9.6 9 1 1 10 10 10 3 Tetratricopeptide repeat TPR_1 PF00515.23 AIO02320.1 - 1.3e-13 49.9 5.1 0.0073 15.8 0.0 8.7 10 0 0 10 10 10 3 Tetratricopeptide repeat TPR_19 PF14559.1 AIO02320.1 - 2.3e-10 40.6 14.1 0.00068 19.9 0.2 6.8 4 2 3 7 7 7 3 Tetratricopeptide repeat TPR_16 PF13432.1 AIO02320.1 - 1.3e-09 38.4 19.8 0.0014 19.2 0.3 6.5 5 1 1 6 6 6 3 Tetratricopeptide repeat TPR_17 PF13431.1 AIO02320.1 - 3.2e-07 30.0 2.0 0.15 12.3 0.0 5.3 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_12 PF13424.1 AIO02320.1 - 3.3e-07 30.1 14.7 0.12 12.2 0.0 6.2 5 2 0 5 5 5 3 Tetratricopeptide repeat TPR_9 PF13371.1 AIO02320.1 - 1.5e-06 27.9 18.0 6.9e-05 22.6 0.1 5.7 6 1 0 6 6 6 2 Tetratricopeptide repeat TPR_14 PF13428.1 AIO02320.1 - 2.6e-06 27.5 21.1 0.0093 16.5 0.0 8.1 4 2 4 8 8 8 1 Tetratricopeptide repeat Apc3 PF12895.2 AIO02320.1 - 0.00017 21.6 9.1 2.9 8.0 0.0 5.5 5 2 0 5 5 5 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.1 AIO02320.1 - 0.00038 20.0 0.0 2.7 8.0 0.0 5.3 5 1 1 6 6 6 1 Tetratricopeptide repeat TPR_15 PF13429.1 AIO02320.1 - 0.006 15.6 0.5 3.4 6.6 0.0 4.0 3 1 0 4 4 4 1 Tetratricopeptide repeat TPR_20 PF14561.1 AIO02320.1 - 0.018 15.1 0.6 0.3 11.2 0.0 3.3 3 1 1 4 4 4 0 Tetratricopeptide repeat XRN_N PF03159.13 AIO02321.1 - 7e-84 280.9 0.0 7e-84 280.9 0.0 2.2 2 1 0 2 2 2 1 XRN 5'-3' exonuclease N-terminus MORN PF02493.15 AIO02323.1 - 3.9e-50 164.6 89.7 4.5e-07 29.2 0.3 19.7 22 0 0 22 22 22 13 MORN repeat DUF1302 PF06980.6 AIO02323.1 - 0.0045 15.6 0.4 0.0073 14.9 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1302) Ras PF00071.17 AIO02324.1 - 1.1e-13 50.8 0.0 1.8e-13 50.2 0.0 1.3 1 0 0 1 1 1 1 Ras family Miro PF08477.8 AIO02324.1 - 4.4e-13 49.7 0.0 1.1e-12 48.5 0.0 1.7 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 AIO02324.1 - 0.022 14.7 0.0 0.042 13.7 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_22 PF13401.1 AIO02324.1 - 0.097 12.8 0.0 0.21 11.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain Arch_ATPase PF01637.13 AIO02324.1 - 0.41 10.2 0.0 1.3 8.7 0.0 1.7 2 0 0 2 2 2 0 Archaeal ATPase DEAD PF00270.24 AIO02326.1 - 4.5e-39 133.6 0.0 1e-38 132.4 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 AIO02326.1 - 6.5e-20 70.7 0.0 1.6e-19 69.4 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF4217 PF13959.1 AIO02326.1 - 2.6e-17 62.0 0.1 5.3e-17 61.1 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) DEAD PF00270.24 AIO02327.1 - 1.6e-43 148.0 0.3 6.2e-43 146.2 0.1 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 AIO02327.1 - 8.3e-25 86.4 0.1 4.1e-24 84.2 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 AIO02327.1 - 0.00095 19.0 0.0 0.0037 17.1 0.0 2.0 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C_2 PF13307.1 AIO02327.1 - 0.032 14.1 0.0 0.15 12.0 0.0 2.1 2 0 0 2 2 2 0 Helicase C-terminal domain Ribosomal_S5_C PF03719.10 AIO02328.1 - 1.6e-15 56.1 0.2 2.5e-15 55.5 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain Ribosomal_S5 PF00333.15 AIO02328.1 - 0.0094 15.6 0.0 0.017 14.8 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S5, N-terminal domain MVP_shoulder PF11978.3 AIO02329.1 - 6.3e-47 158.3 0.0 1.1e-46 157.5 0.0 1.4 1 0 0 1 1 1 1 Shoulder domain Vault PF01505.13 AIO02329.1 - 4e-24 84.3 0.0 1.6e-10 40.8 0.0 4.6 4 0 0 4 4 4 2 Major Vault Protein repeat CBF PF03914.12 AIO02330.1 - 7.4e-38 129.5 2.7 1.1e-37 129.0 0.0 2.4 3 0 0 3 3 3 1 CBF/Mak21 family NOC3p PF07540.6 AIO02330.1 - 0.0001 22.4 0.0 0.00033 20.8 0.0 1.9 1 0 0 1 1 1 1 Nucleolar complex-associated protein Pep_deformylase PF01327.16 AIO02330.1 - 0.058 12.7 0.1 0.11 11.8 0.0 1.5 1 0 0 1 1 1 0 Polypeptide deformylase DUF607 PF04678.8 AIO02330.1 - 0.12 12.2 1.7 0.31 10.9 1.2 1.7 1 0 0 1 1 1 0 Protein of unknown function, DUF607 RPAP3_C PF13877.1 AIO02332.1 - 0.095 12.6 0.0 0.41 10.6 0.0 2.1 1 0 0 1 1 1 0 Potential Monad-binding region of RPAP3 GAS PF13851.1 AIO02334.1 - 4.9e-60 202.1 27.6 4.9e-60 202.1 19.1 3.4 3 1 1 4 4 4 1 Growth-arrest specific micro-tubule binding Filament PF00038.16 AIO02334.1 - 0.76 9.1 65.3 0.28 10.5 3.7 4.8 1 1 3 4 4 4 0 Intermediate filament protein IFP_35_N PF07334.8 AIO02334.1 - 4.2 7.4 15.4 2.4 8.2 1.5 3.7 2 1 1 3 3 3 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus CIDE-N PF02017.10 AIO02335.1 - 0.092 12.5 0.3 11 5.8 0.0 3.0 3 0 0 3 3 3 0 CIDE-N domain IncA PF04156.9 AIO02335.1 - 1.8 8.1 10.8 3.2 7.3 0.5 3.8 3 2 0 3 3 3 0 IncA protein Ribosomal_L37ae PF01780.14 AIO02336.1 - 2e-36 123.7 5.1 2.1e-36 123.6 3.6 1.0 1 0 0 1 1 1 1 Ribosomal L37ae protein family C1_1 PF00130.17 AIO02336.1 - 0.00075 19.1 2.1 0.0011 18.6 1.4 1.2 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) A2L_zn_ribbon PF08792.5 AIO02336.1 - 0.024 14.1 1.2 1.9 8.0 0.0 2.1 2 0 0 2 2 2 0 A2L zinc ribbon domain UPF0547 PF10571.4 AIO02336.1 - 0.046 13.4 1.1 7.1 6.4 0.0 2.2 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 NOB1_Zn_bind PF08772.6 AIO02336.1 - 0.089 12.6 3.7 0.98 9.2 2.6 2.3 1 1 0 1 1 1 0 Nin one binding (NOB1) Zn-ribbon like Carla_C4 PF01623.12 AIO02336.1 - 0.094 12.4 1.6 0.12 12.1 1.1 1.3 1 1 0 1 1 1 0 Carlavirus putative nucleic acid binding protein Zn_Tnp_IS1595 PF12760.2 AIO02336.1 - 0.12 12.2 2.5 0.18 11.6 1.7 1.3 1 0 0 1 1 1 0 Transposase zinc-ribbon domain zf-C4_ClpX PF06689.8 AIO02336.1 - 6.6 6.3 7.0 1.2 8.7 2.1 1.8 2 0 0 2 2 2 0 ClpX C4-type zinc finger zf-RING_2 PF13639.1 AIO02337.1 - 1.1e-11 44.3 9.0 1.8e-11 43.6 6.3 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 AIO02337.1 - 5.2e-11 42.3 7.7 8.1e-11 41.7 5.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 AIO02337.1 - 2.6e-10 39.7 5.8 4.1e-10 39.1 4.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 AIO02337.1 - 6.8e-09 35.2 4.1 9.6e-09 34.7 2.8 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 AIO02337.1 - 9.1e-09 35.0 6.7 1.5e-08 34.3 4.6 1.3 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 AIO02337.1 - 2.3e-07 30.3 1.1 2.3e-07 30.3 0.7 2.0 1 1 1 2 2 2 1 RING-type zinc-finger zf-RING_5 PF14634.1 AIO02337.1 - 3e-07 30.0 5.3 4.7e-07 29.4 3.7 1.3 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.1 AIO02337.1 - 8.2e-05 22.0 4.5 0.00021 20.7 3.1 1.7 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_6 PF14835.1 AIO02337.1 - 0.0016 18.2 4.2 0.003 17.3 2.9 1.4 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-Apc11 PF12861.2 AIO02337.1 - 0.0028 17.4 1.9 0.0051 16.6 1.3 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.2 AIO02337.1 - 0.0097 16.0 8.1 0.028 14.4 5.6 1.8 1 1 0 1 1 1 1 RING-H2 zinc finger Baculo_IE-1 PF05290.6 AIO02337.1 - 0.034 13.8 1.7 0.055 13.1 1.2 1.2 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) zf-Nse PF11789.3 AIO02337.1 - 0.046 13.2 2.0 0.088 12.3 1.4 1.4 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-RING_4 PF14570.1 AIO02337.1 - 0.092 12.3 5.0 0.17 11.4 3.4 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-MIZ PF02891.15 AIO02337.1 - 1.8 8.1 6.1 3 7.4 4.2 1.4 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger IBR PF01485.16 AIO02337.1 - 3.5 7.5 9.1 2.3 8.1 4.9 1.7 1 1 0 1 1 1 0 IBR domain STIL_N PF15253.1 AIO02337.1 - 3.9 6.0 6.5 2.1 6.9 3.1 1.5 2 0 0 2 2 2 0 SCL-interrupting locus protein N-terminus Nucleoside_tran PF01733.13 AIO02338.1 - 1.3e-28 100.0 4.9 5.9e-28 97.9 3.4 2.0 1 1 0 1 1 1 1 Nucleoside transporter MutS_V PF00488.16 AIO02339.1 - 5.5e-63 212.5 0.4 2.5e-62 210.3 0.3 2.0 1 1 0 1 1 1 1 MutS domain V MutS_I PF01624.15 AIO02339.1 - 3e-33 114.2 0.1 6.9e-33 113.0 0.1 1.7 1 0 0 1 1 1 1 MutS domain I MutS_III PF05192.13 AIO02339.1 - 2.3e-24 86.3 5.2 2.4e-23 82.9 3.6 2.5 1 1 0 1 1 1 1 MutS domain III AAA_29 PF13555.1 AIO02339.1 - 0.0031 17.0 0.0 0.0084 15.6 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain ABC_tran PF00005.22 AIO02339.1 - 0.019 15.2 0.0 0.05 13.9 0.0 1.7 1 0 0 1 1 1 0 ABC transporter AAA_25 PF13481.1 AIO02339.1 - 0.094 12.1 0.0 0.19 11.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.1 AIO02339.1 - 0.29 11.4 0.0 3.3 7.9 0.0 2.1 2 0 0 2 2 2 0 AAA domain TLD PF07534.11 AIO02340.1 - 1.3e-22 80.2 0.4 1.5e-12 47.6 0.3 2.4 2 0 0 2 2 2 2 TLD PMM PF03332.8 AIO02341.1 - 3.4e-100 334.1 1.2 3.8e-100 333.9 0.8 1.0 1 0 0 1 1 1 1 Eukaryotic phosphomannomutase Hydrolase_3 PF08282.7 AIO02341.1 - 2.8e-09 36.9 0.0 6.4e-09 35.7 0.0 1.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase S6PP PF05116.8 AIO02341.1 - 2.5e-05 23.7 0.0 0.029 13.6 0.0 2.1 2 0 0 2 2 2 2 Sucrose-6F-phosphate phosphohydrolase HAD PF12710.2 AIO02341.1 - 0.029 14.5 0.1 7.3 6.7 0.0 2.3 1 1 1 2 2 2 0 haloacid dehalogenase-like hydrolase FliG_N PF14842.1 AIO02341.1 - 0.044 13.9 0.5 0.097 12.7 0.0 1.7 2 0 0 2 2 2 0 FliG N-terminal domain TMPIT PF07851.8 AIO02341.1 - 0.045 12.8 0.0 0.064 12.3 0.0 1.2 1 0 0 1 1 1 0 TMPIT-like protein 2OG-FeII_Oxy_2 PF13532.1 AIO02342.1 - 2.8e-11 43.6 0.0 9.4e-11 41.8 0.0 1.8 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 AIO02342.1 - 1.5e-06 28.3 0.0 2.7e-06 27.5 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Metallophos PF00149.23 AIO02343.1 - 1.9e-22 79.6 0.0 2.7e-22 79.1 0.0 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase SQS_PSY PF00494.14 AIO02344.1 - 0.083 12.1 0.2 0.093 12.0 0.1 1.1 1 0 0 1 1 1 0 Squalene/phytoene synthase DUF3900 PF13039.1 AIO02344.1 - 0.12 11.8 0.0 0.14 11.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3900) THOC7 PF05615.8 AIO02346.1 - 0.0028 17.9 18.4 0.026 14.7 1.8 2.5 1 1 1 2 2 2 2 Tho complex subunit 7 Bacillus_HBL PF05791.6 AIO02346.1 - 0.018 14.4 7.8 0.051 12.9 1.9 2.2 2 0 0 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) UBN2 PF14223.1 AIO02346.1 - 0.16 11.7 4.7 0.47 10.2 0.4 2.4 2 0 0 2 2 2 0 gag-polypeptide of LTR copia-type Sigma70_ner PF04546.8 AIO02346.1 - 0.62 9.6 11.7 1.9 8.0 3.1 2.2 2 0 0 2 2 2 0 Sigma-70, non-essential region Syntaxin PF00804.20 AIO02346.1 - 1.1 9.4 20.8 0.69 10.1 3.6 2.9 1 1 0 2 2 2 0 Syntaxin DUF4463 PF14703.1 AIO02346.1 - 4.8 7.7 9.3 1.6 9.3 0.4 3.1 2 1 0 2 2 2 0 Domain of unknown function (DUF4463) DUF3391 PF11871.3 AIO02346.1 - 4.8 7.3 11.0 0.69 10.1 1.1 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF3391) Erp_C PF06780.6 AIO02346.1 - 4.9 6.9 11.1 10 5.9 0.3 3.0 1 1 2 3 3 3 0 Erp protein C-terminus V_ATPase_I PF01496.14 AIO02346.1 - 7.9 4.1 11.0 12 3.5 7.7 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Cpn60_TCP1 PF00118.19 AIO02347.1 - 3.5e-115 385.3 10.3 4.2e-115 385.1 7.2 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family WD40 PF00400.27 AIO02348.1 - 7.8e-07 28.7 9.8 0.00028 20.6 0.5 5.0 5 0 0 5 5 5 3 WD domain, G-beta repeat ALG3 PF05208.8 AIO02349.1 - 4.9e-111 371.5 15.4 5.8e-111 371.2 10.7 1.0 1 0 0 1 1 1 1 ALG3 protein Metallophos PF00149.23 AIO02350.1 - 3.7e-22 78.6 0.0 3.4e-18 65.7 0.0 2.7 2 1 0 2 2 2 2 Calcineurin-like phosphoesterase DUF72 PF01904.13 AIO02351.1 - 3.1e-35 121.9 0.1 1.9e-33 116.1 0.0 2.1 2 0 0 2 2 2 2 Protein of unknown function DUF72 TPR_11 PF13414.1 AIO02352.1 - 8e-18 63.8 4.2 3.1e-11 42.7 0.1 2.5 2 0 0 2 2 2 2 TPR repeat TPR_2 PF07719.12 AIO02352.1 - 1e-12 46.9 6.5 2.8e-06 26.8 0.4 3.7 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.23 AIO02352.1 - 6.2e-09 35.1 5.8 0.00047 19.6 0.1 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_16 PF13432.1 AIO02352.1 - 4.2e-05 24.1 12.7 0.0022 18.6 1.2 3.4 2 1 2 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.1 AIO02352.1 - 0.00048 19.7 0.2 0.024 14.3 0.0 2.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.1 AIO02352.1 - 0.0006 20.2 9.4 0.0006 20.2 1.2 3.8 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_12 PF13424.1 AIO02352.1 - 0.0025 17.6 3.9 0.041 13.8 0.4 2.7 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.1 AIO02352.1 - 0.0032 17.1 0.2 0.042 13.6 0.1 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_9 PF13371.1 AIO02352.1 - 0.3 10.9 4.9 8.2 6.3 0.1 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.1 AIO02352.1 - 0.42 11.1 3.5 0.59 10.7 0.0 3.1 3 1 0 3 3 3 0 Tetratricopeptide repeat F-actin_cap_A PF01267.12 AIO02354.1 - 0.0082 15.2 0.3 0.014 14.4 0.2 1.2 1 0 0 1 1 1 1 F-actin capping protein alpha subunit SPA PF08616.5 AIO02354.1 - 0.048 13.3 0.0 0.13 11.9 0.0 1.7 1 0 0 1 1 1 0 Stabilization of polarity axis Acetyltransf_10 PF13673.1 AIO02355.1 - 0.0021 18.1 0.4 0.01 15.9 0.0 2.3 3 0 0 3 3 3 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 AIO02355.1 - 0.015 15.3 0.1 0.04 13.9 0.0 1.8 2 0 0 2 2 2 0 Acetyltransferase (GNAT) family DnaJ PF00226.26 AIO02356.1 - 3.9e-21 74.5 0.5 5.7e-21 74.0 0.4 1.3 1 0 0 1 1 1 1 DnaJ domain DUF1977 PF09320.6 AIO02356.1 - 8.9e-05 22.6 0.2 0.00098 19.3 0.0 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF1977) DEAD PF00270.24 AIO02359.1 - 3.2e-45 153.6 0.0 1.3e-44 151.6 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 AIO02359.1 - 1.2e-25 89.1 0.1 3.2e-25 87.7 0.1 1.7 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 AIO02359.1 - 0.0022 17.8 0.0 0.019 14.8 0.0 2.3 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_30 PF13604.1 AIO02359.1 - 0.016 14.8 0.0 0.12 11.9 0.0 2.4 2 1 0 2 2 2 0 AAA domain AAA_19 PF13245.1 AIO02359.1 - 0.02 14.6 0.1 0.77 9.5 0.0 2.6 2 0 0 2 2 2 0 Part of AAA domain DsrH PF04077.7 AIO02359.1 - 0.085 12.5 0.0 0.24 11.1 0.0 1.7 1 0 0 1 1 1 0 DsrH like protein HAD_2 PF13419.1 AIO02360.1 - 2e-11 44.4 0.8 0.00053 20.2 0.0 3.3 4 0 0 4 4 4 2 Haloacid dehalogenase-like hydrolase EMP24_GP25L PF01105.19 AIO02361.1 - 9.8e-29 100.3 0.5 1.7e-28 99.5 0.4 1.4 1 1 0 1 1 1 1 emp24/gp25L/p24 family/GOLD FlgD_ig PF13860.1 AIO02361.1 - 0.046 13.4 0.1 0.11 12.2 0.1 1.7 2 0 0 2 2 2 0 FlgD Ig-like domain DUF1049 PF06305.6 AIO02361.1 - 1.7 8.2 5.0 0.91 9.0 1.5 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1049) Dynein_light PF01221.13 AIO02362.1 - 3.9e-20 71.6 0.0 5e-20 71.2 0.0 1.1 1 0 0 1 1 1 1 Dynein light chain type 1 DUF3646 PF12362.3 AIO02362.1 - 0.0033 17.3 0.0 0.0053 16.6 0.0 1.4 1 1 0 1 1 1 1 DNA polymerase III gamma and tau subunits C terminal Nol1_Nop2_Fmu PF01189.12 AIO02363.1 - 1.2e-22 80.6 0.0 1.2e-15 57.6 0.0 3.0 2 1 0 2 2 2 2 NOL1/NOP2/sun family FtsJ PF01728.14 AIO02363.1 - 0.011 15.7 0.0 0.044 13.7 0.0 2.0 2 0 0 2 2 2 0 FtsJ-like methyltransferase Arb1 PF09692.5 AIO02363.1 - 0.047 12.5 0.0 0.071 11.9 0.0 1.2 1 0 0 1 1 1 0 Argonaute siRNA chaperone (ARC) complex subunit Arb1 Y_phosphatase PF00102.22 AIO02364.1 - 1.9e-45 155.0 0.0 4.5e-45 153.8 0.0 1.7 1 1 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.15 AIO02364.1 - 3.6e-05 23.3 0.1 7.8e-05 22.2 0.0 1.5 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.1 AIO02364.1 - 0.1 12.8 0.0 0.43 10.8 0.0 2.0 2 0 0 2 2 2 0 Tyrosine phosphatase family PRK PF00485.13 AIO02364.1 - 0.16 11.4 0.1 0.28 10.7 0.0 1.3 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family Choline_transpo PF04515.7 AIO02367.1 - 2.5e-86 289.4 30.2 2.5e-86 289.4 20.9 2.2 2 0 0 2 2 2 1 Plasma-membrane choline transporter BRCT PF00533.21 AIO02368.1 - 0.0002 21.4 0.0 0.25 11.4 0.0 3.1 2 1 0 2 2 2 2 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.2 AIO02368.1 - 0.00077 19.2 0.5 1.5 8.7 0.0 3.0 3 0 0 3 3 3 2 twin BRCT domain Sec1 PF00995.18 AIO02369.1 - 2.4e-121 406.1 0.1 2.7e-121 405.9 0.1 1.0 1 0 0 1 1 1 1 Sec1 family Spc97_Spc98 PF04130.8 AIO02370.1 - 8.3e-16 57.4 0.0 8.2e-13 47.5 0.0 2.7 3 0 0 3 3 3 2 Spc97 / Spc98 family TGS PF02824.16 AIO02371.1 - 4.6e-18 64.8 0.0 8.4e-18 63.9 0.0 1.5 1 0 0 1 1 1 1 TGS domain MMR_HSR1 PF01926.18 AIO02371.1 - 1.2e-16 60.6 0.0 2.7e-16 59.5 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 AIO02371.1 - 3.7e-09 36.0 0.0 1.2e-08 34.3 0.0 1.8 2 0 0 2 2 2 1 Ferrous iron transport protein B ArgK PF03308.11 AIO02371.1 - 0.0029 16.4 0.2 0.0072 15.1 0.0 1.7 2 0 0 2 2 2 1 ArgK protein GTP_EFTU PF00009.22 AIO02371.1 - 0.004 16.6 0.1 5.7 6.3 0.0 3.4 2 1 0 2 2 2 2 Elongation factor Tu GTP binding domain Miro PF08477.8 AIO02371.1 - 0.012 16.1 0.0 0.063 13.7 0.0 2.2 2 0 0 2 2 2 0 Miro-like protein Dynamin_N PF00350.18 AIO02371.1 - 0.035 13.9 0.3 1.6 8.4 0.0 2.3 1 1 1 2 2 2 0 Dynamin family Guanylate_kin PF00625.16 AIO02372.1 - 2.1e-39 134.8 0.0 4.1e-23 81.7 0.0 3.0 2 1 0 2 2 2 2 Guanylate kinase Rad17 PF03215.10 AIO02372.1 - 7.6e-06 24.8 0.0 1e-05 24.4 0.0 1.1 1 0 0 1 1 1 1 Rad17 cell cycle checkpoint protein AAA_33 PF13671.1 AIO02372.1 - 1e-05 25.4 0.0 0.0015 18.4 0.0 2.6 1 1 1 2 2 2 1 AAA domain DUF258 PF03193.11 AIO02372.1 - 0.00044 19.4 0.0 0.00082 18.5 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_16 PF13191.1 AIO02372.1 - 0.00058 19.8 0.0 0.001 19.0 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 AIO02372.1 - 0.0047 17.0 0.0 0.031 14.4 0.0 2.1 1 1 1 2 2 2 1 AAA domain AAA_29 PF13555.1 AIO02372.1 - 0.0088 15.5 0.0 0.016 14.6 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_17 PF13207.1 AIO02372.1 - 0.011 16.5 0.0 0.022 15.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.22 AIO02372.1 - 0.013 15.8 0.0 0.024 14.9 0.0 1.5 1 0 0 1 1 1 0 ABC transporter RNA_helicase PF00910.17 AIO02372.1 - 0.015 15.4 0.0 0.038 14.1 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA_18 PF13238.1 AIO02372.1 - 0.023 15.0 0.0 0.27 11.5 0.0 2.1 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.18 AIO02372.1 - 0.024 14.6 0.0 0.044 13.7 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase Viral_helicase1 PF01443.13 AIO02372.1 - 0.026 14.0 0.0 0.043 13.3 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase NACHT PF05729.7 AIO02372.1 - 0.03 14.0 0.0 0.078 12.6 0.0 1.7 1 0 0 1 1 1 0 NACHT domain AAA_5 PF07728.9 AIO02372.1 - 0.03 14.0 0.0 0.16 11.7 0.0 2.0 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_28 PF13521.1 AIO02372.1 - 0.037 13.9 0.0 0.12 12.3 0.0 1.9 2 0 0 2 2 2 0 AAA domain Mg_chelatase PF01078.16 AIO02372.1 - 0.06 12.4 0.0 0.12 11.5 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA PF00004.24 AIO02372.1 - 0.13 12.4 0.0 0.22 11.7 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) G-alpha PF00503.15 AIO02372.1 - 0.13 10.8 0.0 0.2 10.2 0.0 1.2 1 0 0 1 1 1 0 G-protein alpha subunit TPR_11 PF13414.1 AIO02374.1 - 5.4e-40 134.8 11.7 5.6e-12 45.1 0.4 6.3 3 2 2 6 6 6 6 TPR repeat TPR_1 PF00515.23 AIO02374.1 - 4.9e-30 101.8 7.0 0.00038 19.9 0.1 8.8 8 1 0 8 8 8 7 Tetratricopeptide repeat TPR_2 PF07719.12 AIO02374.1 - 1e-25 87.5 16.9 0.00024 20.7 0.2 9.8 10 1 0 10 10 9 5 Tetratricopeptide repeat TPR_16 PF13432.1 AIO02374.1 - 2.8e-25 88.3 6.6 0.00018 22.0 0.2 7.1 5 2 2 7 7 7 4 Tetratricopeptide repeat TPR_12 PF13424.1 AIO02374.1 - 3.9e-22 77.9 18.3 1.8e-06 27.8 1.6 6.8 3 2 4 7 7 7 6 Tetratricopeptide repeat TPR_17 PF13431.1 AIO02374.1 - 2.5e-20 70.8 8.5 0.00012 22.0 0.0 8.8 9 0 0 9 9 9 3 Tetratricopeptide repeat TPR_8 PF13181.1 AIO02374.1 - 2.8e-20 70.5 0.1 0.0047 16.6 0.0 8.3 8 1 1 9 9 9 3 Tetratricopeptide repeat Apc3 PF12895.2 AIO02374.1 - 1.3e-17 63.7 14.8 0.00017 21.6 0.0 6.0 3 2 3 6 6 6 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.1 AIO02374.1 - 5.8e-17 61.7 7.5 2.5e-07 30.9 0.3 5.7 3 2 4 7 7 7 3 Tetratricopeptide repeat TPR_14 PF13428.1 AIO02374.1 - 7.4e-17 60.3 11.1 0.00017 21.9 0.4 7.8 3 3 4 8 8 7 4 Tetratricopeptide repeat TPR_9 PF13371.1 AIO02374.1 - 9.2e-14 51.0 12.2 1.6e-05 24.6 0.1 5.1 4 1 1 6 6 5 3 Tetratricopeptide repeat TPR_6 PF13174.1 AIO02374.1 - 5.2e-11 42.2 12.1 0.39 11.2 0.5 8.5 10 0 0 10 10 8 3 Tetratricopeptide repeat TPR_7 PF13176.1 AIO02374.1 - 6.3e-11 41.2 8.2 0.017 14.8 0.1 6.4 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_20 PF14561.1 AIO02374.1 - 3.8e-06 26.9 2.3 0.2 11.8 0.1 4.3 3 1 1 4 4 4 2 Tetratricopeptide repeat ChAPs PF09295.5 AIO02374.1 - 0.00013 20.8 0.7 0.034 12.9 0.0 3.2 1 1 1 4 4 4 1 ChAPs (Chs5p-Arf1p-binding proteins) TPR_4 PF07721.9 AIO02374.1 - 0.00015 21.8 13.8 0.012 15.9 0.9 4.5 3 0 0 3 3 3 1 Tetratricopeptide repeat NARP1 PF12569.3 AIO02374.1 - 0.00032 19.5 1.4 3.3 6.3 0.0 3.5 2 1 0 3 3 3 2 NMDA receptor-regulated protein 1 BTAD PF03704.12 AIO02374.1 - 0.0015 18.8 6.2 0.018 15.3 0.2 3.9 3 1 1 4 4 4 1 Bacterial transcriptional activator domain Paf67 PF10255.4 AIO02374.1 - 0.003 16.4 0.3 0.2 10.4 0.1 2.5 2 1 0 2 2 2 1 RNA polymerase I-associated factor PAF67 Alkyl_sulf_dimr PF14863.1 AIO02374.1 - 0.0038 17.4 0.4 13 5.9 0.0 3.3 3 0 0 3 3 3 0 Alkyl sulfatase dimerisation TPR_10 PF13374.1 AIO02374.1 - 0.0039 17.0 25.9 0.0083 16.0 0.1 7.2 8 0 0 8 8 7 2 Tetratricopeptide repeat DUF3808 PF10300.4 AIO02374.1 - 0.004 15.7 0.3 0.0064 15.1 0.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3808) NatB_MDM20 PF09797.4 AIO02374.1 - 0.0093 14.7 1.7 0.19 10.4 0.1 2.2 2 0 0 2 2 2 1 N-acetyltransferase B complex (NatB) non catalytic subunit Tcf25 PF04910.9 AIO02374.1 - 0.1 11.4 0.9 4.2 6.2 0.0 2.8 2 1 1 3 3 3 0 Transcriptional repressor TCF25 Ribosomal_S18 PF01084.15 AIO02376.1 - 0.00065 19.5 0.0 0.0016 18.2 0.0 1.7 1 0 0 1 1 1 1 Ribosomal protein S18 Glucokinase PF02685.11 AIO02377.1 - 3.7e-15 55.5 0.0 1.6e-14 53.4 0.0 1.9 1 1 0 1 1 1 1 Glucokinase Endonuclease_5 PF04493.9 AIO02378.1 - 2.8e-44 150.9 0.0 3.9e-44 150.4 0.0 1.2 1 0 0 1 1 1 1 Endonuclease V DUF99 PF01949.11 AIO02378.1 - 0.17 10.9 0.0 0.3 10.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function DUF99 adh_short PF00106.20 AIO02379.1 - 1.3e-11 44.6 7.0 3e-10 40.2 4.8 2.7 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 AIO02379.1 - 1.1e-07 31.6 2.3 2.2e-07 30.7 1.6 1.5 1 1 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 AIO02379.1 - 0.00093 19.0 0.1 0.0022 17.8 0.1 1.6 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_2 PF03446.10 AIO02379.1 - 0.0053 16.6 0.1 0.013 15.3 0.1 1.7 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase Epimerase PF01370.16 AIO02379.1 - 0.0059 16.0 0.1 0.013 14.9 0.1 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 AIO02379.1 - 0.074 11.9 0.0 0.21 10.4 0.0 1.7 1 1 0 1 1 1 0 Polysaccharide biosynthesis protein 2-Hacid_dh_C PF02826.14 AIO02379.1 - 0.14 11.3 0.0 0.27 10.3 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Aminotran_1_2 PF00155.16 AIO02380.1 - 1.9e-60 204.7 0.0 2.5e-60 204.3 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 AIO02380.1 - 0.0006 19.0 0.0 0.001 18.3 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase Cys_Met_Meta_PP PF01053.15 AIO02380.1 - 0.0027 16.0 0.0 0.0042 15.4 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DUF772 PF05598.6 AIO02380.1 - 0.15 11.9 0.0 1.3 9.0 0.0 2.5 3 0 0 3 3 3 0 Transposase domain (DUF772) Sterol_MT_C PF08498.5 AIO02382.1 - 2.8e-24 84.8 0.1 4.9e-24 84.0 0.1 1.4 1 0 0 1 1 1 1 Sterol methyltransferase C-terminal Methyltransf_11 PF08241.7 AIO02382.1 - 9.5e-17 61.2 0.2 5.7e-16 58.7 0.0 2.3 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_31 PF13847.1 AIO02382.1 - 2.3e-13 49.9 0.1 7.8e-13 48.2 0.1 1.9 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_23 PF13489.1 AIO02382.1 - 5.4e-09 35.9 0.0 2.7e-08 33.6 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 AIO02382.1 - 3.5e-08 33.8 0.1 1.3e-06 28.8 0.0 2.8 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_25 PF13649.1 AIO02382.1 - 9.3e-08 32.3 0.0 2e-07 31.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 AIO02382.1 - 2.2e-07 30.2 0.0 3.8e-07 29.4 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family CMAS PF02353.15 AIO02382.1 - 4.9e-07 29.0 0.2 8.4e-07 28.3 0.2 1.3 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_18 PF12847.2 AIO02382.1 - 1.1e-06 29.1 0.0 2.2e-05 24.9 0.0 2.6 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_26 PF13659.1 AIO02382.1 - 0.00027 20.9 0.0 0.015 15.3 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.9 AIO02382.1 - 0.0051 16.1 0.0 0.18 11.1 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_15 PF09445.5 AIO02382.1 - 0.0072 15.8 0.5 0.011 15.2 0.4 1.3 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase UPF0020 PF01170.13 AIO02382.1 - 0.024 14.1 0.0 0.043 13.3 0.0 1.4 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 EF-hand_7 PF13499.1 AIO02383.1 - 0.0013 18.8 0.0 0.005 16.9 0.0 1.9 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.27 AIO02383.1 - 0.0033 16.6 0.0 2.1 7.8 0.0 2.5 2 0 0 2 2 2 2 EF hand RAG2_PHD PF13341.1 AIO02383.1 - 0.013 15.4 0.0 0.026 14.4 0.0 1.6 1 0 0 1 1 1 0 RAG2 PHD domain EF-hand_6 PF13405.1 AIO02383.1 - 0.028 14.2 0.0 7.4 6.7 0.0 2.6 2 0 0 2 2 2 0 EF-hand domain Cullin_Nedd8 PF10557.4 AIO02384.1 - 6.4e-18 64.3 0.2 1.3e-17 63.3 0.1 1.5 1 0 0 1 1 1 1 Cullin protein neddylation domain Cullin PF00888.17 AIO02384.1 - 0.32 9.5 0.0 0.47 8.9 0.0 1.1 1 0 0 1 1 1 0 Cullin family Peptidase_S9 PF00326.16 AIO02385.1 - 6e-33 113.8 0.3 1.3e-32 112.7 0.0 1.7 2 0 0 2 2 2 1 Prolyl oligopeptidase family DPPIV_N PF00930.16 AIO02385.1 - 1e-24 86.8 0.0 1.7e-24 86.1 0.0 1.3 1 0 0 1 1 1 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Abhydrolase_5 PF12695.2 AIO02385.1 - 3e-05 23.8 0.0 6.2e-05 22.7 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S15 PF02129.13 AIO02385.1 - 0.073 12.4 0.1 0.32 10.3 0.0 1.9 2 0 0 2 2 2 0 X-Pro dipeptidyl-peptidase (S15 family) DUF2681 PF10883.3 AIO02385.1 - 0.083 13.1 0.5 0.39 10.9 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2681) Fimbrial_PilY2 PF14481.1 AIO02386.1 - 0.039 13.3 0.1 0.067 12.6 0.1 1.5 1 0 0 1 1 1 0 Type 4 fimbrial biogenesis protein PilY2 EF-hand_8 PF13833.1 AIO02386.1 - 0.046 13.3 0.1 0.18 11.4 0.0 1.9 2 0 0 2 2 2 0 EF-hand domain pair FYVE PF01363.16 AIO02387.1 - 0.00029 20.6 6.4 0.00073 19.3 4.4 1.7 1 0 0 1 1 1 1 FYVE zinc finger HTH_29 PF13551.1 AIO02387.1 - 0.23 11.6 1.9 1.2 9.2 0.1 2.2 2 0 0 2 2 2 0 Winged helix-turn helix zf-B_box PF00643.19 AIO02387.1 - 0.34 10.8 6.3 3.2 7.7 1.8 2.3 2 0 0 2 2 2 0 B-box zinc finger FYVE_2 PF02318.11 AIO02387.1 - 4 7.3 6.7 18 5.2 4.6 2.1 1 1 0 1 1 1 0 FYVE-type zinc finger His_Phos_2 PF00328.17 AIO02390.1 - 1.8e-18 67.0 0.0 7.2e-13 48.5 0.0 2.2 1 1 0 2 2 2 2 Histidine phosphatase superfamily (branch 2) RRM_6 PF14259.1 AIO02391.1 - 0.16 12.0 0.0 0.35 10.8 0.0 1.7 1 1 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Auts2 PF15336.1 AIO02391.1 - 0.74 9.8 10.2 11 5.9 0.0 2.7 2 1 0 2 2 2 0 Autism susceptibility gene 2 protein WD40 PF00400.27 AIO02393.1 - 5e-27 92.7 14.4 3.7e-07 29.7 0.5 6.8 7 0 0 7 7 7 5 WD domain, G-beta repeat Nic96 PF04097.9 AIO02394.1 - 2.2e-93 313.4 0.1 2.8e-93 313.1 0.0 1.1 1 0 0 1 1 1 1 Nup93/Nic96 SNAPc_SNAP43 PF09808.4 AIO02395.1 - 0.046 13.3 0.0 0.07 12.8 0.0 1.2 1 0 0 1 1 1 0 Small nuclear RNA activating complex (SNAPc), subunit SNAP43 DEAD PF00270.24 AIO02396.1 - 5.3e-25 87.8 0.0 2.2e-24 85.8 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 AIO02396.1 - 5.5e-17 61.4 0.0 2e-16 59.5 0.0 2.1 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Helicase_C_2 PF13307.1 AIO02396.1 - 0.0012 18.8 0.0 0.072 13.0 0.0 2.4 2 0 0 2 2 2 1 Helicase C-terminal domain NAD_binding_3 PF03447.11 AIO02396.1 - 0.035 14.5 0.1 0.11 12.9 0.1 1.9 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain FA_hydroxylase PF04116.8 AIO02397.1 - 1.6e-13 51.0 15.8 1.6e-13 51.0 10.9 2.9 3 0 0 3 3 3 1 Fatty acid hydroxylase superfamily His_Phos_2 PF00328.17 AIO02398.1 - 4.4e-25 88.7 0.1 1.9e-24 86.6 0.1 1.8 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) HEAT PF02985.17 AIO02399.1 - 0.45 10.7 10.7 1.7 8.9 0.0 4.4 4 0 0 4 4 4 0 HEAT repeat GDPD PF03009.12 AIO02401.1 - 8.6e-36 123.7 0.0 1.3e-35 123.2 0.0 1.3 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family His_Phos_2 PF00328.17 AIO02402.1 - 3.1e-21 76.1 0.1 2.5e-20 73.1 0.1 2.0 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) RCC1 PF00415.13 AIO02403.1 - 1.3e-20 73.3 15.2 3.4e-05 23.9 0.0 5.9 6 0 0 6 6 6 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 AIO02403.1 - 1e-18 66.4 21.3 2.7e-06 26.8 1.5 4.2 4 0 0 4 4 4 3 Regulator of chromosome condensation (RCC1) repeat Mur_ligase_M PF08245.7 AIO02404.1 - 7.4e-12 45.7 0.1 2.4e-11 44.0 0.0 1.9 1 1 0 1 1 1 1 Mur ligase middle domain Sulfatase PF00884.18 AIO02404.1 - 0.17 11.0 0.0 0.62 9.1 0.0 1.7 1 1 1 2 2 2 0 Sulfatase VRR_NUC PF08774.6 AIO02405.1 - 1.9e-16 59.8 0.0 4.5e-16 58.6 0.0 1.7 1 0 0 1 1 1 1 VRR-NUC domain Pkinase PF00069.20 AIO02406.1 - 2.4e-25 89.1 0.0 6.9e-10 38.5 0.0 3.4 3 0 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.12 AIO02406.1 - 1.7e-11 43.7 0.0 4.8e-10 38.9 0.0 2.6 2 0 0 2 2 2 1 Protein tyrosine kinase Kdo PF06293.9 AIO02406.1 - 0.54 9.2 0.1 1.1 8.2 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family PCI PF01399.22 AIO02407.1 - 9.3e-05 22.7 0.0 0.12 12.6 0.0 3.2 3 0 0 3 3 3 2 PCI domain Methyltransf_11 PF08241.7 AIO02408.1 - 3.4e-11 43.4 0.0 1.3e-08 35.1 0.0 3.0 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 AIO02408.1 - 6.4e-08 32.8 0.0 3.2e-07 30.6 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 AIO02408.1 - 2.6e-06 27.9 0.0 0.0017 18.9 0.0 2.5 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_23 PF13489.1 AIO02408.1 - 2.1e-05 24.3 0.0 3.6e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 AIO02408.1 - 7.1e-05 23.2 0.0 0.00055 20.3 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 AIO02408.1 - 0.00034 20.6 0.0 0.00058 19.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 AIO02408.1 - 0.00059 19.4 0.0 1.7 8.2 0.0 3.1 2 1 0 2 2 2 2 Methyltransferase domain DUF3895 PF13034.1 AIO02408.1 - 0.1 12.0 0.0 0.22 11.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3895) 2-oxoacid_dh PF00198.18 AIO02409.1 - 9.8e-77 257.3 0.0 1.3e-76 256.8 0.0 1.2 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) E3_binding PF02817.12 AIO02409.1 - 3.5e-12 45.7 0.1 9.8e-12 44.3 0.1 1.9 1 0 0 1 1 1 1 e3 binding domain Biotin_lipoyl PF00364.17 AIO02409.1 - 6.9e-11 41.6 0.0 3.7e-10 39.2 0.0 2.2 2 0 0 2 2 2 1 Biotin-requiring enzyme Gag_spuma PF03276.9 AIO02409.1 - 0.72 8.1 4.6 1 7.6 3.2 1.1 1 0 0 1 1 1 0 Spumavirus gag protein Metallophos_2 PF12850.2 AIO02410.1 - 8.6e-07 28.9 0.0 1.6e-06 28.0 0.0 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos_3 PF14582.1 AIO02410.1 - 0.16 11.0 0.1 0.75 8.8 0.0 1.8 2 0 0 2 2 2 0 Metallophosphoesterase, calcineurin superfamily Pentapeptide_4 PF13599.1 AIO02412.1 - 3.6e-12 45.9 14.9 2.3e-08 33.7 5.3 2.6 2 1 1 3 3 3 2 Pentapeptide repeats (9 copies) Pentapeptide PF00805.17 AIO02412.1 - 2.3e-11 42.6 9.4 2e-06 26.9 0.2 4.2 1 1 3 5 5 5 5 Pentapeptide repeats (8 copies) Pentapeptide_3 PF13576.1 AIO02412.1 - 4.5e-09 36.0 9.9 8.1e-06 25.6 0.4 2.9 1 1 0 2 2 2 2 Pentapeptide repeats (9 copies) Adeno_100 PF02438.11 AIO02413.1 - 0.047 11.9 2.4 0.68 8.0 0.7 2.1 2 0 0 2 2 2 0 Late 100kD protein DUF2894 PF11445.3 AIO02413.1 - 0.057 13.6 10.2 1 9.6 2.6 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2894) Ly-6_related PF06579.7 AIO02413.1 - 0.078 13.1 0.0 0.17 12.0 0.0 1.6 1 0 0 1 1 1 0 Caenorhabditis elegans ly-6-related protein KfrA_N PF11740.3 AIO02413.1 - 4.7 7.6 20.3 0.17 12.3 6.8 2.7 2 1 0 2 2 2 0 Plasmid replication region DNA-binding N-term Peptidase_M41 PF01434.13 AIO02415.1 - 2.1e-63 213.6 0.3 3e-63 213.1 0.2 1.2 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.24 AIO02415.1 - 2.6e-41 140.8 0.0 4.8e-41 140.0 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.1 AIO02415.1 - 5.1e-06 26.0 1.0 0.00082 18.8 0.1 2.4 1 1 1 2 2 2 1 AAA domain AAA_5 PF07728.9 AIO02415.1 - 1.8e-05 24.4 0.0 4.6e-05 23.1 0.0 1.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 AIO02415.1 - 2.1e-05 24.6 0.2 0.00061 19.9 0.1 2.5 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.1 AIO02415.1 - 5.1e-05 23.1 0.0 0.00014 21.7 0.0 1.7 2 0 0 2 2 1 1 AAA domain AAA_16 PF13191.1 AIO02415.1 - 5.8e-05 23.1 0.1 0.0061 16.5 0.0 2.4 1 1 1 2 2 2 1 AAA ATPase domain AAA_17 PF13207.1 AIO02415.1 - 9.9e-05 23.1 0.0 0.0003 21.5 0.0 1.8 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.7 AIO02415.1 - 0.00014 20.9 0.0 0.00032 19.8 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus NACHT PF05729.7 AIO02415.1 - 0.00077 19.1 0.1 0.012 15.3 0.0 2.4 2 0 0 2 2 2 1 NACHT domain AAA_19 PF13245.1 AIO02415.1 - 0.00083 19.0 0.1 0.0027 17.4 0.0 1.9 1 0 0 1 1 1 1 Part of AAA domain TIP49 PF06068.8 AIO02415.1 - 0.0011 17.7 0.0 0.0024 16.6 0.0 1.5 1 0 0 1 1 1 1 TIP49 C-terminus IstB_IS21 PF01695.12 AIO02415.1 - 0.0012 18.3 0.2 0.003 17.0 0.1 1.7 1 1 0 1 1 1 1 IstB-like ATP binding protein AAA_28 PF13521.1 AIO02415.1 - 0.0013 18.7 0.0 0.0062 16.5 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 AIO02415.1 - 0.0029 17.9 0.0 0.0072 16.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.16 AIO02415.1 - 0.004 16.3 0.2 0.011 14.9 0.2 1.6 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI Zeta_toxin PF06414.7 AIO02415.1 - 0.0048 16.0 0.0 0.0097 15.0 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin Rad17 PF03215.10 AIO02415.1 - 0.011 14.5 0.0 0.016 13.9 0.0 1.2 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein AAA_33 PF13671.1 AIO02415.1 - 0.015 15.1 0.0 0.035 13.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_2 PF07724.9 AIO02415.1 - 0.018 14.9 0.0 0.065 13.1 0.0 2.0 1 1 0 1 1 1 0 AAA domain (Cdc48 subfamily) RNA_helicase PF00910.17 AIO02415.1 - 0.028 14.5 0.1 0.1 12.7 0.0 1.9 2 0 0 2 2 2 0 RNA helicase Reprolysin_4 PF13583.1 AIO02415.1 - 0.056 12.9 0.0 0.15 11.5 0.0 1.6 1 1 1 2 2 2 0 Metallo-peptidase family M12B Reprolysin-like KaiC PF06745.8 AIO02415.1 - 0.065 12.3 0.1 0.7 8.9 0.0 2.5 3 0 0 3 3 3 0 KaiC ABC_tran PF00005.22 AIO02415.1 - 0.068 13.4 0.6 0.29 11.4 0.2 2.2 2 0 0 2 2 2 0 ABC transporter Arch_ATPase PF01637.13 AIO02415.1 - 0.096 12.3 0.0 0.31 10.7 0.0 1.8 1 1 1 2 2 2 0 Archaeal ATPase Parvo_NS1 PF01057.12 AIO02415.1 - 0.21 10.3 0.0 0.38 9.5 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Peptidase_M50B PF13398.1 AIO02415.1 - 0.51 9.6 0.0 0.51 9.6 0.0 1.5 2 0 0 2 2 1 0 Peptidase M50B-like HEAT_EZ PF13513.1 AIO02416.1 - 0.0003 21.1 7.7 0.012 16.0 0.0 5.4 6 0 0 6 6 6 1 HEAT-like repeat B56 PF01603.15 AIO02416.1 - 0.0035 15.9 0.0 0.0077 14.8 0.0 1.5 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) HEAT PF02985.17 AIO02416.1 - 0.0045 16.9 0.1 34 4.8 0.0 5.2 5 0 0 5 5 5 1 HEAT repeat IBN_N PF03810.14 AIO02416.1 - 0.011 15.6 0.1 0.19 11.6 0.1 2.9 1 1 0 1 1 1 0 Importin-beta N-terminal domain Tyr_Deacylase PF02580.11 AIO02417.1 - 2.5e-39 134.5 0.0 2.7e-39 134.4 0.0 1.0 1 0 0 1 1 1 1 D-Tyr-tRNA(Tyr) deacylase Acetyltransf_1 PF00583.19 AIO02419.1 - 1.2e-15 57.2 0.1 1.7e-15 56.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 AIO02419.1 - 1e-05 25.5 0.0 1.7e-05 24.8 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 AIO02419.1 - 0.00017 21.6 0.0 0.00022 21.3 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 AIO02419.1 - 0.004 17.0 0.0 0.007 16.2 0.0 1.3 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase FR47 PF08445.5 AIO02419.1 - 0.0091 15.7 0.0 0.025 14.2 0.0 1.7 2 0 0 2 2 2 1 FR47-like protein Acetyltransf_9 PF13527.1 AIO02419.1 - 0.021 14.6 0.5 0.041 13.7 0.4 1.6 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Mec-17 PF05301.6 AIO02419.1 - 0.027 14.3 0.0 0.044 13.7 0.0 1.3 1 0 0 1 1 1 0 Touch receptor neuron protein Mec-17 Acetyltransf_6 PF13480.1 AIO02419.1 - 0.061 13.2 0.3 0.13 12.1 0.2 1.8 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain MFS_1 PF07690.11 AIO02420.1 - 9.7e-12 44.2 46.2 1.3e-10 40.5 19.8 2.9 2 1 0 3 3 3 2 Major Facilitator Superfamily Nodulin-like PF06813.8 AIO02420.1 - 1.1e-09 37.9 11.6 1.1e-09 37.9 8.0 2.3 2 1 0 2 2 2 1 Nodulin-like TP6A_N PF04406.9 AIO02422.1 - 0.017 14.7 0.0 0.9 9.2 0.0 2.4 2 0 0 2 2 2 0 Type IIB DNA topoisomerase DUF2399 PF09664.5 AIO02422.1 - 0.031 14.1 0.0 0.067 13.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function C-terminus (DUF2399) NDK PF00334.14 AIO02423.1 - 0.00083 19.1 0.0 0.022 14.5 0.0 2.8 2 0 0 2 2 2 1 Nucleoside diphosphate kinase OB_NTP_bind PF07717.11 AIO02427.1 - 2.3e-24 85.4 0.0 2.9e-23 81.8 0.0 2.5 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.18 AIO02427.1 - 4.1e-20 71.7 0.0 1.4e-19 69.9 0.0 2.0 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.26 AIO02427.1 - 5.4e-13 48.6 0.0 1.4e-12 47.2 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 AIO02427.1 - 6.5e-08 32.2 0.7 2.8e-07 30.2 0.1 2.3 3 0 0 3 3 3 1 DEAD/DEAH box helicase AAA_22 PF13401.1 AIO02427.1 - 3e-05 24.1 0.6 0.00025 21.1 0.0 2.7 2 0 0 2 2 2 1 AAA domain Zot PF05707.7 AIO02427.1 - 0.022 14.1 0.1 0.058 12.8 0.0 1.8 2 0 0 2 2 2 0 Zonular occludens toxin (Zot) AAA_25 PF13481.1 AIO02427.1 - 0.03 13.7 0.0 0.097 12.0 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.1 AIO02427.1 - 0.045 13.2 0.0 0.12 11.9 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Flavi_DEAD PF07652.9 AIO02427.1 - 0.06 13.1 0.0 0.14 11.9 0.0 1.6 1 0 0 1 1 1 0 Flavivirus DEAD domain ABC_tran PF00005.22 AIO02427.1 - 0.063 13.5 0.2 0.89 9.8 0.1 2.8 1 1 0 1 1 1 0 ABC transporter AAA_19 PF13245.1 AIO02427.1 - 0.064 13.0 0.1 0.22 11.3 0.0 1.9 1 0 0 1 1 1 0 Part of AAA domain AAA_23 PF13476.1 AIO02427.1 - 0.095 13.0 0.0 0.095 13.0 0.0 2.6 2 1 0 2 2 1 0 AAA domain Phytochelatin PF05023.9 AIO02428.1 - 0.0026 16.7 0.0 5.5 5.8 0.0 4.3 5 0 0 5 5 5 1 Phytochelatin synthase Endonuc-MspI PF09208.5 AIO02428.1 - 0.29 10.1 0.3 0.78 8.7 0.1 1.7 2 0 0 2 2 2 0 Restriction endonuclease MspI Apolipoprotein PF01442.13 AIO02429.1 - 0.0053 16.2 2.3 0.0065 15.9 1.6 1.2 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain Cast PF10174.4 AIO02429.1 - 0.0058 14.7 2.4 0.0061 14.6 1.6 1.1 1 0 0 1 1 1 1 RIM-binding protein of the cytomatrix active zone RasGAP_C PF03836.10 AIO02429.1 - 0.011 15.4 0.6 0.012 15.3 0.4 1.2 1 0 0 1 1 1 0 RasGAP C-terminus Bacillus_HBL PF05791.6 AIO02429.1 - 0.011 15.1 1.4 0.013 14.8 1.0 1.1 1 0 0 1 1 1 0 Bacillus haemolytic enterotoxin (HBL) Spc24 PF08286.6 AIO02429.1 - 0.013 15.2 3.9 0.016 14.8 2.7 1.1 1 0 0 1 1 1 0 Spc24 subunit of Ndc80 DUF972 PF06156.8 AIO02429.1 - 0.022 15.0 2.6 0.044 14.1 1.8 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF972) DUF2968 PF11180.3 AIO02429.1 - 0.027 13.8 4.4 0.031 13.6 3.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) GAS PF13851.1 AIO02429.1 - 0.034 13.3 3.2 0.04 13.1 2.2 1.1 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding TraC PF07820.7 AIO02429.1 - 0.036 14.2 1.1 0.049 13.8 0.8 1.1 1 0 0 1 1 1 0 TraC-like protein Baculo_PEP_C PF04513.7 AIO02429.1 - 0.047 13.5 0.4 0.056 13.2 0.3 1.2 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus FUSC PF04632.7 AIO02429.1 - 0.048 12.1 1.6 0.05 12.0 1.1 1.0 1 0 0 1 1 1 0 Fusaric acid resistance protein family HCR PF07111.7 AIO02429.1 - 0.065 11.2 3.6 0.07 11.1 2.5 1.1 1 0 0 1 1 1 0 Alpha helical coiled-coil rod protein (HCR) Spc7 PF08317.6 AIO02429.1 - 0.086 11.4 2.9 0.085 11.4 2.0 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein Hemerythrin PF01814.18 AIO02429.1 - 0.087 12.9 0.6 0.1 12.7 0.4 1.1 1 0 0 1 1 1 0 Hemerythrin HHE cation binding domain DUF484 PF04340.7 AIO02429.1 - 0.11 12.0 2.7 0.12 11.8 1.8 1.1 1 0 0 1 1 1 0 Protein of unknown function, DUF484 Cob_adeno_trans PF01923.13 AIO02429.1 - 0.11 12.2 1.2 0.13 12.0 0.9 1.1 1 0 0 1 1 1 0 Cobalamin adenosyltransferase AATF-Che1 PF13339.1 AIO02429.1 - 0.12 12.5 2.7 0.14 12.2 1.9 1.1 1 0 0 1 1 1 0 Apoptosis antagonizing transcription factor TBPIP PF07106.8 AIO02429.1 - 0.13 11.8 1.9 0.15 11.5 1.3 1.2 1 0 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DUF904 PF06005.7 AIO02429.1 - 0.14 12.5 8.1 2.4 8.4 5.6 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF904) GvpG PF05120.7 AIO02429.1 - 0.15 11.8 5.9 0.21 11.4 4.1 1.3 1 1 0 1 1 1 0 Gas vesicle protein G APG6 PF04111.7 AIO02429.1 - 0.17 10.9 5.1 0.16 10.9 3.5 1.0 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF948 PF06103.6 AIO02429.1 - 0.19 11.6 0.8 0.32 10.8 0.4 1.6 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF948) OmpH PF03938.9 AIO02429.1 - 0.2 11.5 5.8 0.21 11.4 4.0 1.1 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) SseC PF04888.7 AIO02429.1 - 0.24 10.7 3.7 0.31 10.3 2.6 1.2 1 0 0 1 1 1 0 Secretion system effector C (SseC) like family IncA PF04156.9 AIO02429.1 - 0.26 10.8 7.3 0.43 10.1 5.1 1.3 1 1 0 1 1 1 0 IncA protein Herpes_UL25 PF01499.11 AIO02429.1 - 0.26 9.5 2.5 0.27 9.4 1.7 1.0 1 0 0 1 1 1 0 Herpesvirus UL25 family DUF342 PF03961.8 AIO02429.1 - 0.28 9.5 1.4 0.29 9.4 0.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Mnd1 PF03962.10 AIO02429.1 - 0.29 10.7 4.3 0.34 10.5 1.5 1.6 1 1 1 2 2 2 0 Mnd1 family GrpE PF01025.14 AIO02429.1 - 0.38 10.2 3.8 0.45 10.0 2.6 1.2 1 0 0 1 1 1 0 GrpE DUF4404 PF14357.1 AIO02429.1 - 0.58 10.6 4.1 0.79 10.1 2.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4404) bZIP_2 PF07716.10 AIO02429.1 - 0.63 9.9 7.7 4.9 7.0 1.0 2.1 2 0 0 2 2 2 0 Basic region leucine zipper TMF_DNA_bd PF12329.3 AIO02429.1 - 0.68 9.7 9.6 1.6 8.5 6.5 1.7 1 1 0 1 1 1 0 TATA element modulatory factor 1 DNA binding TACC PF05010.9 AIO02429.1 - 0.72 9.5 7.3 0.97 9.1 5.1 1.1 1 0 0 1 1 1 0 Transforming acidic coiled-coil-containing protein (TACC) Borrelia_P83 PF05262.6 AIO02429.1 - 0.85 7.8 3.9 0.86 7.8 2.7 1.0 1 0 0 1 1 1 0 Borrelia P83/100 protein T2SM PF04612.7 AIO02429.1 - 1.1 9.0 4.6 0.46 10.2 1.4 1.7 1 1 1 2 2 2 0 Type II secretion system (T2SS), protein M Wbp11 PF09429.5 AIO02429.1 - 1.1 9.2 4.6 0.91 9.5 1.4 1.9 1 1 1 2 2 2 0 WW domain binding protein 11 DASH_Dad2 PF08654.5 AIO02429.1 - 1.2 9.2 6.0 0.56 10.2 2.6 1.6 2 0 0 2 2 1 0 DASH complex subunit Dad2 DivIC PF04977.10 AIO02429.1 - 1.5 8.3 9.7 5 6.6 0.7 2.2 1 1 1 2 2 2 0 Septum formation initiator DUF883 PF05957.8 AIO02429.1 - 2.1 8.8 4.9 6.2 7.3 2.5 1.9 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) CENP-Q PF13094.1 AIO02429.1 - 8.5 6.3 10.4 23 4.9 7.2 1.6 1 1 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit Chlorosome_CsmC PF11098.3 AIO02430.1 - 0.0058 16.3 0.1 0.011 15.4 0.1 1.3 1 0 0 1 1 1 1 Chlorosome envelope protein C Ribosomal_S24e PF01282.14 AIO02431.1 - 7.2e-28 96.2 0.0 1.2e-27 95.4 0.0 1.5 1 1 0 1 1 1 1 Ribosomal protein S24e Motile_Sperm PF00635.21 AIO02432.1 - 1.5e-11 43.8 0.0 0.0082 15.7 0.0 6.6 7 0 0 7 7 7 4 MSP (Major sperm protein) domain ABC2_membrane PF01061.19 AIO02433.1 - 1.3e-36 125.7 18.5 2.8e-36 124.6 12.8 1.6 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.22 AIO02433.1 - 7.9e-24 84.5 0.0 1.3e-23 83.7 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 AIO02433.1 - 1e-07 32.2 0.7 0.001 19.1 0.0 2.2 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.1 AIO02433.1 - 0.00058 20.0 0.5 0.0053 16.9 0.0 2.5 2 1 0 2 2 2 1 AAA domain SMC_N PF02463.14 AIO02433.1 - 0.00064 19.0 0.0 0.0093 15.2 0.0 2.1 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 AIO02433.1 - 0.00064 19.7 1.9 0.0012 18.8 0.2 2.2 2 1 0 2 2 2 1 AAA ATPase domain AAA_29 PF13555.1 AIO02433.1 - 0.0016 17.9 0.0 0.004 16.6 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain DUF258 PF03193.11 AIO02433.1 - 0.0065 15.6 0.0 0.01 14.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_17 PF13207.1 AIO02433.1 - 0.025 15.3 0.0 0.046 14.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.1 AIO02433.1 - 0.031 14.0 0.9 0.076 12.7 0.2 2.0 2 0 0 2 2 2 0 Part of AAA domain AAA_25 PF13481.1 AIO02433.1 - 0.034 13.5 0.1 0.074 12.4 0.1 1.5 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.1 AIO02433.1 - 0.045 13.7 0.3 0.1 12.5 0.2 1.6 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 AIO02433.1 - 0.053 13.8 0.0 0.12 12.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.1 AIO02433.1 - 0.085 12.7 0.3 0.31 10.9 0.0 2.0 2 0 0 2 2 2 0 AAA domain ArgK PF03308.11 AIO02433.1 - 0.11 11.3 0.3 0.17 10.6 0.2 1.2 1 0 0 1 1 1 0 ArgK protein AAA_23 PF13476.1 AIO02433.1 - 0.24 11.6 0.0 0.41 10.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.1 AIO02433.1 - 0.27 10.7 2.0 0.3 10.6 0.1 1.9 2 0 0 2 2 2 0 AAA domain MCM PF00493.18 AIO02434.1 - 8.1e-06 24.8 0.0 1.4e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 MCM2/3/5 family AAA_16 PF13191.1 AIO02434.1 - 0.0028 17.6 0.1 0.011 15.7 0.1 2.0 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 AIO02434.1 - 0.072 13.2 0.0 0.21 11.7 0.0 1.8 1 0 0 1 1 1 0 AAA domain Arch_ATPase PF01637.13 AIO02434.1 - 0.073 12.7 0.0 1.7 8.2 0.0 2.1 2 0 0 2 2 2 0 Archaeal ATPase AAA PF00004.24 AIO02434.1 - 0.091 12.9 0.0 0.29 11.3 0.1 1.8 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) PHF5 PF03660.9 AIO02436.1 - 7.9e-36 122.3 10.3 8.9e-36 122.2 7.1 1.0 1 0 0 1 1 1 1 PHF5-like protein DZR PF12773.2 AIO02436.1 - 0.26 11.1 9.8 0.12 12.2 3.6 2.0 1 1 1 2 2 2 0 Double zinc ribbon FYVE_2 PF02318.11 AIO02436.1 - 1.5 8.7 10.5 0.49 10.3 5.4 1.6 2 0 0 2 2 2 0 FYVE-type zinc finger TF_Zn_Ribbon PF08271.7 AIO02436.1 - 3.4 7.0 8.2 1.9 7.8 0.4 2.4 2 0 0 2 2 2 0 TFIIB zinc-binding DUF4051 PF13260.1 AIO02436.1 - 4.3 6.7 8.7 5.7 6.3 2.0 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF4051) zf-C3HC4_2 PF13923.1 AIO02436.1 - 6.2 6.9 10.2 1.4 8.9 3.3 2.3 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 AIO02437.1 - 1.9e-13 50.0 2.7 1.9e-13 50.0 1.8 1.9 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.1 AIO02437.1 - 1.9e-08 34.2 2.8 1.9e-08 34.2 1.9 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 AIO02437.1 - 7e-08 32.0 1.0 7e-08 32.0 0.7 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 AIO02437.1 - 7.3e-08 32.4 1.6 1.8e-07 31.1 1.1 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 AIO02437.1 - 1.6e-07 30.8 0.6 1.6e-07 30.8 0.4 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 AIO02437.1 - 4.4e-07 29.5 1.2 9.4e-07 28.4 0.8 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-Apc11 PF12861.2 AIO02437.1 - 0.015 15.1 2.6 0.07 12.9 1.8 2.0 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger ING PF12998.2 AIO02437.1 - 0.049 13.9 0.8 0.083 13.1 0.5 1.3 1 0 0 1 1 1 0 Inhibitor of growth proteins N-terminal histone-binding zf-RING_4 PF14570.1 AIO02437.1 - 0.2 11.2 1.3 0.45 10.1 0.9 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain FANCL_C PF11793.3 AIO02437.1 - 0.32 10.9 6.5 0.31 11.0 1.7 2.8 2 1 0 2 2 2 0 FANCL C-terminal domain PI3_PI4_kinase PF00454.22 AIO02438.1 - 3e-17 62.9 0.0 9.9e-17 61.1 0.0 1.8 2 0 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase NUC194 PF08163.7 AIO02438.1 - 1e-07 31.1 0.0 2e-07 30.2 0.0 1.3 1 0 0 1 1 1 1 NUC194 domain FATC PF02260.15 AIO02438.1 - 0.00013 21.3 0.0 0.00057 19.2 0.0 2.2 1 0 0 1 1 1 1 FATC domain ATP-grasp_2 PF08442.5 AIO02439.1 - 2.2e-64 216.5 3.7 3.2e-64 216.0 2.6 1.2 1 0 0 1 1 1 1 ATP-grasp domain Ligase_CoA PF00549.14 AIO02439.1 - 1e-23 83.6 2.4 2.2e-23 82.5 0.6 2.3 2 0 0 2 2 2 1 CoA-ligase Succ_CoA_lig PF13607.1 AIO02439.1 - 0.038 13.6 0.5 0.093 12.3 0.3 1.6 1 0 0 1 1 1 0 Succinyl-CoA ligase like flavodoxin domain SID-1_RNA_chan PF13965.1 AIO02440.1 - 0.027 12.6 0.6 0.023 12.8 0.4 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 DUF1430 PF07242.6 AIO02441.1 - 0.052 13.6 1.0 0.1 12.7 0.2 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1430) SYS1 PF09801.4 AIO02441.1 - 0.057 13.4 0.5 0.069 13.1 0.3 1.2 1 0 0 1 1 1 0 Integral membrane protein S linking to the trans Golgi network DUF4499 PF14934.1 AIO02441.1 - 0.072 13.0 0.4 0.19 11.6 0.3 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4499) LtrA PF06772.6 AIO02441.1 - 0.074 11.9 0.1 0.093 11.6 0.1 1.1 1 0 0 1 1 1 0 Bacterial low temperature requirement A protein (LtrA) Bromodomain PF00439.20 AIO02442.1 - 3.4e-22 78.1 0.0 5.2e-22 77.5 0.0 1.3 1 0 0 1 1 1 1 Bromodomain GTP1_OBG PF01018.17 AIO02443.1 - 5.2e-35 120.4 4.1 7.2e-35 119.9 2.9 1.2 1 0 0 1 1 1 1 GTP1/OBG MMR_HSR1 PF01926.18 AIO02443.1 - 3.3e-17 62.5 0.0 4.9e-17 61.9 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 AIO02443.1 - 5.1e-06 25.8 0.0 9e-05 21.8 0.0 2.2 2 0 0 2 2 2 1 Ferrous iron transport protein B rRNA_proc-arch PF13234.1 AIO02444.1 - 2.7e-56 190.7 0.5 7.3e-56 189.2 0.4 1.7 2 0 0 2 2 2 1 rRNA-processing arch domain DSHCT PF08148.7 AIO02444.1 - 1e-49 168.2 2.1 1e-49 168.2 0.2 2.0 2 0 0 2 2 2 1 DSHCT (NUC185) domain DEAD PF00270.24 AIO02444.1 - 1.4e-25 89.7 0.9 4.9e-24 84.7 0.0 2.7 3 0 0 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.26 AIO02444.1 - 7.9e-07 28.8 0.0 1.9e-06 27.6 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 AIO02444.1 - 0.00057 19.7 0.0 0.0025 17.6 0.0 2.0 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_19 PF13245.1 AIO02444.1 - 0.00058 19.5 0.0 0.0015 18.2 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain Zot PF05707.7 AIO02444.1 - 0.0019 17.7 0.0 0.007 15.8 0.0 1.8 1 1 0 1 1 1 1 Zonular occludens toxin (Zot) PhoH PF02562.11 AIO02444.1 - 0.0038 16.5 0.0 0.0092 15.2 0.0 1.6 1 0 0 1 1 1 1 PhoH-like protein Arch_ATPase PF01637.13 AIO02444.1 - 0.0053 16.4 0.4 0.031 13.9 0.0 2.2 2 0 0 2 2 2 1 Archaeal ATPase FlxA PF14282.1 AIO02444.1 - 0.0065 16.3 1.6 0.015 15.2 1.1 1.5 1 0 0 1 1 1 1 FlxA-like protein CobA_CobO_BtuR PF02572.10 AIO02444.1 - 0.035 13.7 0.0 0.11 12.1 0.0 1.8 1 0 0 1 1 1 0 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP T2SE PF00437.15 AIO02444.1 - 0.043 12.7 0.0 0.12 11.3 0.0 1.7 1 0 0 1 1 1 0 Type II/IV secretion system protein GSHPx PF00255.14 AIO02445.1 - 1.3e-26 92.0 0.0 1.6e-26 91.7 0.0 1.1 1 0 0 1 1 1 1 Glutathione peroxidase AhpC-TSA PF00578.16 AIO02445.1 - 0.0058 16.3 0.0 0.008 15.8 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 AIO02445.1 - 0.14 11.7 0.0 0.18 11.3 0.0 1.1 1 0 0 1 1 1 0 Redoxin RNase_PH PF01138.16 AIO02446.1 - 1.6e-28 99.6 1.3 1.9e-28 99.4 0.3 1.5 2 0 0 2 2 2 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.10 AIO02446.1 - 1.9e-07 30.8 0.0 4.8e-07 29.6 0.0 1.7 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 DUF1623 PF07785.6 AIO02446.1 - 0.04 13.8 1.2 0.073 13.0 0.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1623) Adap_comp_sub PF00928.16 AIO02447.1 - 2.8e-54 183.9 0.0 3.5e-54 183.6 0.0 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 AIO02447.1 - 2.1e-08 34.0 1.7 3.9e-08 33.1 1.2 1.4 1 0 0 1 1 1 1 Clathrin adaptor complex small chain RRM_1 PF00076.17 AIO02448.1 - 5.1e-08 32.4 0.0 8.3e-08 31.7 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 AIO02448.1 - 5.4e-06 26.1 0.1 8.1e-06 25.6 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 AIO02448.1 - 0.0023 17.8 0.0 0.0036 17.2 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 AIO02448.1 - 0.022 14.6 0.0 0.031 14.1 0.0 1.2 1 0 0 1 1 1 0 RNA binding motif Phage_Gp23 PF10669.4 AIO02448.1 - 0.078 13.0 1.7 0.11 12.5 1.2 1.2 1 0 0 1 1 1 0 Protein gp23 (Bacteriophage A118) Peroxin-22 PF12827.2 AIO02449.1 - 0.08 12.6 0.0 0.08 12.6 0.0 1.1 1 0 0 1 1 1 0 Peroxisomal biogenesis protein family Cullin PF00888.17 AIO02450.1 - 4.8e-49 167.3 0.2 6.2e-49 167.0 0.2 1.1 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.4 AIO02450.1 - 1.6e-12 47.0 0.0 5.8e-12 45.2 0.0 2.0 2 0 0 2 2 2 1 Cullin protein neddylation domain HbrB PF08539.6 AIO02450.1 - 0.013 15.3 0.1 0.027 14.3 0.0 1.5 1 0 0 1 1 1 0 HbrB-like Fibrillarin PF01269.12 AIO02451.1 - 1.7e-104 347.7 0.0 1.9e-104 347.5 0.0 1.0 1 0 0 1 1 1 1 Fibrillarin GCD14 PF08704.5 AIO02451.1 - 0.00024 20.6 0.0 0.00033 20.2 0.0 1.2 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit PCMT PF01135.14 AIO02451.1 - 0.011 15.3 0.1 0.019 14.5 0.1 1.4 1 1 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) BPL_LplA_LipB PF03099.14 AIO02452.1 - 3.8e-07 30.1 0.0 8e-07 29.1 0.0 1.5 1 1 0 1 1 1 1 Biotin/lipoate A/B protein ligase family Thioredoxin PF00085.15 AIO02453.1 - 0.022 14.4 0.1 0.11 12.2 0.0 2.1 2 0 0 2 2 2 0 Thioredoxin vATP-synt_E PF01991.13 AIO02454.1 - 6.2e-40 136.5 6.2 7.1e-40 136.4 4.3 1.0 1 0 0 1 1 1 1 ATP synthase (E/31 kDa) subunit Glyco_hydro_57 PF03065.10 AIO02454.1 - 0.085 11.7 1.2 0.12 11.3 0.8 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 57 Macscav_rec PF03523.8 AIO02455.1 - 0.063 13.0 0.1 0.13 12.0 0.1 1.5 1 0 0 1 1 1 0 Macrophage scavenger receptor EF-hand_8 PF13833.1 AIO02456.1 - 0.00017 21.1 0.0 0.0026 17.3 0.0 2.4 2 0 0 2 2 2 1 EF-hand domain pair Pro_isomerase PF00160.16 AIO02457.1 - 1.7e-34 119.2 0.0 1.9e-34 119.1 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD ArfGap PF01412.13 AIO02459.1 - 1.3e-23 82.9 0.0 2.1e-23 82.3 0.0 1.3 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf TBCC PF07986.7 AIO02460.1 - 5.3e-25 87.1 0.6 1e-24 86.2 0.4 1.4 1 0 0 1 1 1 1 Tubulin binding cofactor C CDC37_N PF03234.9 AIO02460.1 - 0.54 10.5 4.9 0.78 10.0 3.4 1.2 1 0 0 1 1 1 0 Cdc37 N terminal kinase binding cobW PF02492.14 AIO02461.1 - 2.4e-44 150.8 0.1 3.3e-44 150.4 0.1 1.2 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.9 AIO02461.1 - 0.0015 18.2 0.0 0.0027 17.3 0.0 1.4 1 0 0 1 1 1 1 Cobalamin synthesis protein cobW C-terminal domain AAA_19 PF13245.1 AIO02461.1 - 0.0081 15.8 0.9 0.028 14.1 0.1 2.3 2 1 0 2 2 2 1 Part of AAA domain ATP_bind_1 PF03029.12 AIO02461.1 - 0.015 14.8 0.1 0.035 13.6 0.1 1.6 1 1 0 1 1 1 0 Conserved hypothetical ATP binding protein AAA_33 PF13671.1 AIO02461.1 - 0.021 14.6 0.0 0.037 13.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.1 AIO02461.1 - 0.032 14.3 0.0 0.073 13.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.1 AIO02461.1 - 0.04 13.4 0.0 0.087 12.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_18 PF13238.1 AIO02461.1 - 0.081 13.2 0.2 0.31 11.3 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.1 AIO02461.1 - 0.11 12.4 0.4 0.42 10.5 0.0 1.9 2 0 0 2 2 2 0 AAA ATPase domain UPF0004 PF00919.15 AIO02461.1 - 0.15 11.9 1.7 0.31 10.8 0.4 2.0 2 0 0 2 2 2 0 Uncharacterized protein family UPF0004 Guanylate_cyc PF00211.15 AIO02462.1 - 5.1e-38 130.2 0.0 9.4e-38 129.4 0.0 1.4 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain DUF1935 PF09149.5 AIO02462.1 - 4.8e-27 93.9 0.0 1e-26 92.9 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1935) IncA PF04156.9 AIO02462.1 - 3.6 7.1 4.5 6 6.4 3.1 1.3 1 0 0 1 1 1 0 IncA protein zf-CCHC PF00098.18 AIO02463.1 - 6.2e-20 70.1 79.3 0.00033 20.4 0.7 10.4 11 0 0 11 11 11 8 Zinc knuckle zf-CCHC_2 PF13696.1 AIO02463.1 - 0.0019 17.6 53.7 0.0046 16.4 0.3 7.6 3 2 4 7 7 7 5 Zinc knuckle NYN PF01936.13 AIO02463.1 - 0.14 12.4 0.0 0.35 11.1 0.0 1.7 1 1 0 1 1 1 0 NYN domain Topoisom_bac PF01131.15 AIO02464.1 - 1e-96 324.2 0.0 3.7e-96 322.4 0.0 1.8 2 0 0 2 2 2 1 DNA topoisomerase Toprim PF01751.17 AIO02464.1 - 2.9e-16 59.2 0.0 6.8e-16 58.0 0.0 1.7 1 0 0 1 1 1 1 Toprim domain zf-GRF PF06839.7 AIO02464.1 - 1.1e-06 28.4 8.0 2.6e-06 27.2 0.5 2.7 2 0 0 2 2 2 1 GRF zinc finger zf-C4_Topoisom PF01396.14 AIO02464.1 - 5.6e-06 25.7 0.1 5.6e-06 25.7 0.1 4.9 5 0 0 5 5 5 1 Topoisomerase DNA binding C4 zinc finger Cys_rich_CPCC PF14206.1 AIO02464.1 - 0.018 14.6 1.5 0.32 10.5 0.7 2.7 2 0 0 2 2 2 0 Cysteine-rich CPCC Lar_restr_allev PF14354.1 AIO02464.1 - 0.095 13.0 8.3 2.7 8.3 0.5 4.0 3 0 0 3 3 3 0 Restriction alleviation protein Lar HypA PF01155.14 AIO02464.1 - 0.74 9.5 12.5 0.63 9.7 0.2 3.9 3 1 0 3 3 3 0 Hydrogenase expression/synthesis hypA family zf-TFIIB PF13453.1 AIO02464.1 - 2.3 7.5 9.8 4.3 6.6 0.5 3.9 3 0 0 3 3 3 0 Transcription factor zinc-finger 14-3-3 PF00244.15 AIO02465.1 - 3.6e-91 304.4 0.3 4.1e-91 304.2 0.2 1.0 1 0 0 1 1 1 1 14-3-3 protein TPR_12 PF13424.1 AIO02465.1 - 0.27 11.1 3.5 0.76 9.7 0.2 2.6 2 1 1 3 3 3 0 Tetratricopeptide repeat Reo_sigmaC PF04582.7 AIO02466.1 - 6.6 5.8 24.6 0.52 9.4 3.4 3.6 2 1 1 3 3 3 0 Reovirus sigma C capsid protein GMC_oxred_N PF00732.14 AIO02467.1 - 1.2e-49 169.0 0.1 1.9e-49 168.3 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 AIO02467.1 - 5.7e-21 75.3 0.1 9.8e-21 74.5 0.1 1.4 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 AIO02467.1 - 7e-07 28.4 7.6 3.2e-05 23.0 3.5 3.2 1 1 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 AIO02467.1 - 1.2e-05 24.3 7.8 0.0015 17.4 1.5 2.5 3 0 0 3 3 3 2 FAD binding domain Pyr_redox_2 PF07992.9 AIO02467.1 - 4.8e-05 23.3 0.2 0.00022 21.1 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 AIO02467.1 - 0.00012 21.0 1.9 0.052 12.4 1.1 2.1 2 0 0 2 2 2 2 Glucose inhibited division protein A NAD_binding_8 PF13450.1 AIO02467.1 - 0.00051 20.0 1.2 0.014 15.3 0.7 2.6 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 AIO02467.1 - 0.0022 16.9 0.9 0.0035 16.3 0.6 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein HI0933_like PF03486.9 AIO02467.1 - 0.0048 15.4 1.2 0.0086 14.5 0.8 1.4 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_3 PF13738.1 AIO02467.1 - 0.012 15.6 0.0 0.14 12.1 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 AIO02467.1 - 0.041 12.9 5.1 0.67 8.9 2.2 2.2 2 0 0 2 2 2 0 FAD dependent oxidoreductase ComFB PF10719.4 AIO02468.1 - 0.16 11.7 0.5 0.32 10.7 0.3 1.4 1 0 0 1 1 1 0 Late competence development protein ComFB DUF1712 PF08217.6 AIO02470.1 - 5.4e-06 24.9 0.0 2.4e-05 22.8 0.0 1.9 2 0 0 2 2 2 1 Fungal domain of unknown function (DUF1712) Ribosomal_L22e PF01776.12 AIO02472.1 - 9.9e-40 135.0 3.4 1.2e-39 134.7 2.4 1.1 1 0 0 1 1 1 1 Ribosomal L22e protein family ECH PF00378.15 AIO02473.1 - 1.4e-13 50.5 0.0 3.5e-09 36.1 0.0 2.7 3 0 0 3 3 3 2 Enoyl-CoA hydratase/isomerase family ECH_C PF13766.1 AIO02473.1 - 3e-11 43.5 0.1 1.2e-07 31.8 0.0 3.6 3 0 0 3 3 3 2 2-enoyl-CoA Hydratase C-terminal region Macro PF01661.16 AIO02474.1 - 1.3e-05 25.1 0.0 2.1e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 Macro domain Actin PF00022.14 AIO02476.1 - 4.2e-95 318.4 0.0 4.8e-95 318.2 0.0 1.0 1 0 0 1 1 1 1 Actin NR_Repeat PF14046.1 AIO02476.1 - 0.12 12.0 0.5 0.37 10.5 0.4 1.8 1 0 0 1 1 1 0 Nuclear receptor repeat DUF3595 PF12166.3 AIO02479.1 - 6.1e-110 367.9 0.1 8e-110 367.5 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3595) Bromodomain PF00439.20 AIO02481.1 - 2.4e-13 49.7 0.0 6.6e-13 48.3 0.0 1.8 2 0 0 2 2 2 1 Bromodomain YtzH PF14165.1 AIO02481.1 - 0.12 12.6 0.2 0.33 11.2 0.0 1.9 2 0 0 2 2 2 0 YtzH-like protein Ribosomal_L29e PF01779.12 AIO02484.1 - 8.3e-18 63.9 5.4 8.3e-18 63.9 3.8 1.7 2 0 0 2 2 2 1 Ribosomal L29e protein family Tymo_45kd_70kd PF03251.8 AIO02484.1 - 0.0055 15.4 0.0 0.0057 15.3 0.0 1.1 1 0 0 1 1 1 1 Tymovirus 45/70Kd protein Ribosomal_L29e PF01779.12 AIO02485.1 - 8.3e-18 63.9 5.4 8.3e-18 63.9 3.8 1.7 2 0 0 2 2 2 1 Ribosomal L29e protein family Tymo_45kd_70kd PF03251.8 AIO02485.1 - 0.0055 15.4 0.0 0.0057 15.3 0.0 1.1 1 0 0 1 1 1 1 Tymovirus 45/70Kd protein adh_short PF00106.20 AIO02486.1 - 1.5e-23 83.5 0.3 3.2e-23 82.4 0.2 1.6 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 AIO02486.1 - 8.8e-12 45.0 1.1 1.8e-07 30.9 0.2 2.4 2 0 0 2 2 2 2 KR domain Methyltransf_31 PF13847.1 AIO02486.1 - 0.00065 19.3 0.0 0.0012 18.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain adh_short_C2 PF13561.1 AIO02486.1 - 0.0016 18.3 0.0 0.0024 17.6 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Ubie_methyltran PF01209.13 AIO02486.1 - 0.049 12.7 0.0 0.077 12.1 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Pyr_redox PF00070.22 AIO02486.1 - 0.067 13.6 0.4 0.13 12.6 0.3 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase DUF1776 PF08643.5 AIO02486.1 - 0.093 11.8 0.0 0.14 11.2 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) Vps26 PF03643.10 AIO02487.1 - 3.2e-54 183.5 0.6 4e-54 183.2 0.4 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 Arrestin_N PF00339.24 AIO02487.1 - 9.6e-07 28.7 0.5 0.0014 18.5 0.2 3.1 2 1 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain CRAL_TRIO PF00650.15 AIO02488.1 - 2.4e-28 98.6 0.0 3.5e-28 98.0 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 AIO02488.1 - 0.025 14.7 0.2 0.055 13.6 0.2 1.6 1 0 0 1 1 1 0 CRAL/TRIO, N-terminal domain Snf7 PF03357.16 AIO02489.1 - 1.8e-27 95.7 30.6 1.8e-27 95.7 21.2 1.8 1 1 1 2 2 2 1 Snf7 V_ATPase_I PF01496.14 AIO02489.1 - 0.83 7.4 12.2 0.94 7.2 8.5 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Cupin_8 PF13621.1 AIO02489.1 - 9.5 5.6 6.5 4.7 6.6 3.1 1.5 1 1 1 2 2 2 0 Cupin-like domain Glyco_transf_25 PF01755.12 AIO02490.1 - 1.1e-11 44.7 0.0 1e-10 41.6 0.0 2.3 1 1 0 1 1 1 1 Glycosyltransferase family 25 (LPS biosynthesis protein) NIPSNAP PF07978.8 AIO02491.1 - 3.1e-15 55.9 0.1 6.1e-15 55.0 0.0 1.5 2 0 0 2 2 2 1 NIPSNAP Transket_pyr PF02779.19 AIO02492.1 - 1.8e-56 190.4 0.1 5.1e-56 188.9 0.0 1.8 2 0 0 2 2 2 1 Transketolase, pyrimidine binding domain E1_dh PF00676.15 AIO02492.1 - 2.1e-50 171.1 0.0 3.5e-50 170.4 0.0 1.2 1 0 0 1 1 1 1 Dehydrogenase E1 component SMAP PF15477.1 AIO02493.1 - 1.6e-12 47.5 6.0 1.6e-12 47.5 4.1 2.1 2 1 0 2 2 2 1 Small acidic protein family DUF2870 PF11069.3 AIO02494.1 - 2.6e-30 104.3 0.1 9.5e-30 102.5 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF2870) DASH_Spc34 PF08657.5 AIO02494.1 - 0.0052 16.4 0.1 0.0087 15.7 0.1 1.4 1 0 0 1 1 1 1 DASH complex subunit Spc34 TarH PF02203.10 AIO02494.1 - 0.028 14.2 0.8 0.051 13.4 0.6 1.4 1 0 0 1 1 1 0 Tar ligand binding domain homologue Tox-REase-2 PF15646.1 AIO02495.1 - 0.017 15.0 1.6 0.036 13.9 0.2 2.1 2 0 0 2 2 2 0 Restriction endonuclease fold toxin 2 DivIC PF04977.10 AIO02495.1 - 0.039 13.4 6.2 0.05 13.1 0.0 2.9 2 0 0 2 2 2 0 Septum formation initiator DUF904 PF06005.7 AIO02495.1 - 0.07 13.4 0.0 0.07 13.4 0.0 3.1 2 1 0 2 2 2 0 Protein of unknown function (DUF904) HALZ PF02183.13 AIO02495.1 - 0.071 12.8 2.4 0.2 11.4 0.1 2.9 3 0 0 3 3 3 0 Homeobox associated leucine zipper Shugoshin_N PF07558.6 AIO02495.1 - 0.97 9.2 4.5 2.1 8.1 3.1 1.6 1 0 0 1 1 1 0 Shugoshin N-terminal coiled-coil region DUF972 PF06156.8 AIO02495.1 - 1.4 9.2 7.4 1.2 9.4 0.0 3.2 2 1 0 2 2 2 0 Protein of unknown function (DUF972) MCC-bdg_PDZ PF10506.4 AIO02496.1 - 0.022 14.5 0.9 0.06 13.1 0.6 1.9 1 1 0 1 1 1 0 PDZ domain of MCC-2 bdg protein for Usher syndrome Prefoldin_2 PF01920.15 AIO02496.1 - 0.024 14.3 1.2 0.092 12.5 0.2 2.0 2 0 0 2 2 2 0 Prefoldin subunit Syntaxin-6_N PF09177.6 AIO02496.1 - 0.16 12.3 0.8 2.9 8.3 0.2 2.3 1 1 1 2 2 2 0 Syntaxin 6, N-terminal CENP-Q PF13094.1 AIO02496.1 - 0.33 10.9 4.7 0.68 9.9 3.2 1.7 1 1 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit Erythro-docking PF09277.6 AIO02496.1 - 0.43 10.3 4.7 2.3 7.9 0.1 3.0 3 1 0 3 3 3 0 Erythronolide synthase, docking DUF3846 PF12957.2 AIO02498.1 - 1.8e-17 62.8 0.0 2.6e-14 52.7 0.0 2.5 2 0 0 2 2 2 2 Domain of unknown function (DUF3846) TPR_11 PF13414.1 AIO02498.1 - 4.5e-11 42.2 12.0 6.8e-09 35.2 0.4 2.7 1 1 1 2 2 2 2 TPR repeat TPR_1 PF00515.23 AIO02498.1 - 0.00052 19.5 0.2 0.00052 19.5 0.1 3.6 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.12 AIO02498.1 - 0.037 13.9 0.1 0.037 13.9 0.1 3.5 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_9 PF13371.1 AIO02498.1 - 0.57 10.0 3.5 0.39 10.6 0.8 2.0 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_16 PF13432.1 AIO02498.1 - 5.9 7.6 9.6 5.9 7.6 2.8 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat SQS_PSY PF00494.14 AIO02500.1 - 1.5e-12 47.3 0.0 2.5e-12 46.6 0.0 1.2 1 0 0 1 1 1 1 Squalene/phytoene synthase SRP54 PF00448.17 AIO02501.1 - 4.1e-55 186.2 0.1 9.4e-55 185.1 0.1 1.6 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain SRP-alpha_N PF04086.8 AIO02501.1 - 2.9e-16 59.7 5.0 9.8e-16 57.9 3.4 1.8 1 1 0 1 1 1 1 Signal recognition particle, alpha subunit, N-terminal AAA_22 PF13401.1 AIO02501.1 - 2e-07 31.1 0.0 9.4e-07 29.0 0.0 2.2 1 1 0 1 1 1 1 AAA domain SRP54_N PF02881.14 AIO02501.1 - 4e-05 23.6 0.0 8.6e-05 22.5 0.0 1.5 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain AAA_30 PF13604.1 AIO02501.1 - 0.00014 21.5 0.1 0.00014 21.5 0.1 1.7 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 AIO02501.1 - 0.0004 20.0 3.2 0.0085 15.8 0.0 3.2 2 1 1 3 3 3 1 Part of AAA domain CbiA PF01656.18 AIO02501.1 - 0.00064 19.1 0.1 0.0048 16.3 0.0 2.3 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain Zeta_toxin PF06414.7 AIO02501.1 - 0.00064 18.8 0.0 0.015 14.4 0.0 2.5 2 0 0 2 2 2 1 Zeta toxin ETF PF01012.16 AIO02501.1 - 0.00085 19.0 0.5 0.16 11.6 0.0 2.5 2 0 0 2 2 2 1 Electron transfer flavoprotein domain NTPase_1 PF03266.10 AIO02501.1 - 0.0011 18.6 0.0 1.5 8.4 0.0 2.4 2 0 0 2 2 2 2 NTPase DAP3 PF10236.4 AIO02501.1 - 0.0031 16.5 0.0 0.0057 15.6 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial ribosomal death-associated protein 3 ArsA_ATPase PF02374.10 AIO02501.1 - 0.01 14.9 0.2 0.049 12.6 0.0 2.0 2 0 0 2 2 2 0 Anion-transporting ATPase NACHT PF05729.7 AIO02501.1 - 0.018 14.7 0.0 0.68 9.5 0.0 2.6 3 0 0 3 3 3 0 NACHT domain APS_kinase PF01583.15 AIO02501.1 - 0.03 13.9 0.0 0.087 12.4 0.0 1.8 2 0 0 2 2 2 0 Adenylylsulphate kinase AAA_10 PF12846.2 AIO02501.1 - 0.04 13.3 0.0 0.2 11.0 0.0 2.0 2 1 0 2 2 2 0 AAA-like domain AAA_16 PF13191.1 AIO02501.1 - 0.05 13.5 0.0 0.18 11.7 0.0 2.1 1 1 0 1 1 1 0 AAA ATPase domain ABC_tran PF00005.22 AIO02501.1 - 0.1 12.9 0.0 0.24 11.7 0.0 1.6 1 0 0 1 1 1 0 ABC transporter Cep57_MT_bd PF06657.8 AIO02501.1 - 0.1 12.5 0.2 0.67 9.9 0.0 2.3 2 0 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 AAA_14 PF13173.1 AIO02501.1 - 0.12 12.3 0.0 0.38 10.6 0.0 1.9 2 0 0 2 2 1 0 AAA domain Thymidylate_kin PF02223.12 AIO02501.1 - 0.13 11.6 0.0 0.45 9.8 0.0 1.9 2 0 0 2 2 2 0 Thymidylate kinase DUF2009 PF09418.5 AIO02502.1 - 8.8e-113 377.4 3.1 7.2e-112 374.4 2.2 2.1 1 1 0 1 1 1 1 Protein of unknown function (DUF2009) PALP PF00291.20 AIO02503.1 - 3.3e-55 187.4 1.6 3.7e-55 187.3 1.1 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme EF-hand_8 PF13833.1 AIO02506.1 - 1.2e-06 28.0 0.0 0.01 15.4 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_7 PF13499.1 AIO02506.1 - 5e-06 26.5 0.1 1.2e-05 25.3 0.0 1.7 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.1 AIO02506.1 - 0.00013 21.5 0.0 0.38 10.7 0.0 2.3 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.27 AIO02506.1 - 0.00036 19.6 0.0 0.15 11.4 0.0 2.4 2 0 0 2 2 2 2 EF hand DUF3647 PF12363.3 AIO02506.1 - 0.12 12.5 0.1 1.2 9.2 0.0 1.9 1 1 1 2 2 2 0 Phage protein Shisa PF13908.1 AIO02507.1 - 0.00081 19.6 0.5 0.0014 18.8 0.3 1.4 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator IncA PF04156.9 AIO02507.1 - 0.0032 17.0 1.4 0.0045 16.5 1.0 1.1 1 0 0 1 1 1 1 IncA protein MLANA PF14991.1 AIO02507.1 - 0.0084 16.1 0.1 0.016 15.2 0.0 1.5 1 0 0 1 1 1 1 Protein melan-A DAG1 PF05454.6 AIO02507.1 - 0.02 14.0 0.1 0.035 13.3 0.1 1.3 1 0 0 1 1 1 0 Dystroglycan (Dystrophin-associated glycoprotein 1) Neur_chan_memb PF02932.11 AIO02507.1 - 0.057 13.2 0.5 0.077 12.8 0.4 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region SAGA-Tad1 PF12767.2 AIO02507.1 - 1.5 8.4 6.0 0.27 10.8 1.8 1.4 2 0 0 2 2 2 0 Transcriptional regulator of RNA polII, SAGA, subunit DUF3157 PF11355.3 AIO02508.1 - 0.043 13.0 0.0 0.048 12.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3157) WD40 PF00400.27 AIO02509.1 - 5.8e-15 54.5 14.5 6e-05 22.7 0.1 5.6 5 0 0 5 5 5 4 WD domain, G-beta repeat NUDIX PF00293.23 AIO02511.1 - 1e-12 47.8 0.0 1.6e-12 47.2 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain EF-hand_7 PF13499.1 AIO02513.1 - 2.2e-25 88.5 5.4 7.8e-15 54.7 0.4 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.27 AIO02513.1 - 5.7e-25 84.6 9.9 3.6e-06 25.8 0.8 4.2 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.1 AIO02513.1 - 3.3e-20 70.1 7.2 3.9e-05 23.1 0.0 4.5 4 2 1 5 5 5 4 EF-hand domain EF-hand_8 PF13833.1 AIO02513.1 - 7.9e-19 67.0 7.8 5.6e-10 38.6 0.6 3.2 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_5 PF13202.1 AIO02513.1 - 1e-16 59.4 13.5 9.4e-05 21.5 0.3 4.5 5 0 0 5 5 5 4 EF hand EF-hand_9 PF14658.1 AIO02513.1 - 4.5e-06 26.4 0.5 0.06 13.2 0.0 2.7 2 2 1 3 3 3 2 EF-hand domain EF-hand_4 PF12763.2 AIO02513.1 - 4.4e-05 23.1 4.7 0.008 15.8 0.5 3.0 1 1 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand IFR3_antag PF14754.1 AIO02513.1 - 0.057 12.3 0.0 0.078 11.9 0.0 1.2 1 0 0 1 1 1 0 Papain-like auto-proteinase Pkinase PF00069.20 AIO02514.1 - 1e-54 185.4 0.0 2.1e-53 181.1 0.0 2.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AIO02514.1 - 6.5e-32 110.6 0.0 3.3e-31 108.3 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase PAS PF00989.19 AIO02514.1 - 4.1e-05 23.3 0.0 0.00015 21.5 0.0 1.9 1 0 0 1 1 1 1 PAS fold PAS_9 PF13426.1 AIO02514.1 - 0.00063 20.0 0.0 0.0018 18.6 0.0 1.8 1 0 0 1 1 1 1 PAS domain RIO1 PF01163.17 AIO02514.1 - 0.0014 18.0 0.0 0.013 14.8 0.0 2.2 2 0 0 2 2 2 1 RIO1 family Kinase-like PF14531.1 AIO02514.1 - 0.0015 17.5 0.0 0.007 15.3 0.0 2.0 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 AIO02514.1 - 0.0025 17.6 0.0 0.0052 16.5 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Amastin PF07344.6 AIO02514.1 - 0.021 14.4 3.5 0.054 13.1 2.4 1.7 1 0 0 1 1 1 0 Amastin surface glycoprotein OKR_DC_1_N PF03709.10 AIO02514.1 - 0.023 14.7 0.2 0.083 12.9 0.1 2.0 2 0 0 2 2 2 0 Orn/Lys/Arg decarboxylase, N-terminal domain PAS_4 PF08448.5 AIO02514.1 - 0.033 14.2 0.0 1.8 8.6 0.0 2.5 2 0 0 2 2 2 0 PAS fold YrbL-PhoP_reg PF10707.4 AIO02514.1 - 0.09 12.0 0.0 0.27 10.5 0.0 1.9 1 1 0 1 1 1 0 PhoP regulatory network protein YrbL FTH PF01827.22 AIO02514.1 - 0.15 11.6 0.0 0.35 10.4 0.0 1.6 1 0 0 1 1 1 0 FTH domain FtsK_SpoIIIE PF01580.13 AIO02517.1 - 8.1e-05 22.1 0.0 0.00019 20.9 0.0 1.6 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA_19 PF13245.1 AIO02517.1 - 0.011 15.4 0.0 0.034 13.8 0.0 1.8 1 0 0 1 1 1 0 Part of AAA domain Clp1 PF06807.9 AIO02517.1 - 0.012 15.3 0.0 0.039 13.7 0.0 1.8 1 1 0 1 1 1 0 Pre-mRNA cleavage complex II protein Clp1 DUF498 PF04430.9 AIO02518.1 - 9.2e-23 79.9 0.0 1.5e-22 79.1 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF498/DUF598) tRNA_int_endo PF01974.12 AIO02519.1 - 6.3e-14 51.5 0.0 1e-13 50.8 0.0 1.3 1 0 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain Ribosomal_L34e PF01199.13 AIO02520.1 - 2.4e-28 98.1 4.2 2.4e-28 98.1 2.9 2.2 2 1 0 2 2 2 1 Ribosomal protein L34e NARP1 PF12569.3 AIO02520.1 - 0.19 10.4 9.4 0.22 10.2 6.5 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 DUF2335 PF10097.4 AIO02520.1 - 5.9 6.5 6.1 21 4.8 4.2 2.0 1 1 0 1 1 1 0 Predicted membrane protein (DUF2335) Ribosomal_S27e PF01667.12 AIO02521.1 - 4.1e-22 77.4 2.8 5.1e-22 77.1 2.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S27 IBR PF01485.16 AIO02521.1 - 0.0015 18.3 1.4 0.0021 17.8 1.0 1.2 1 0 0 1 1 1 1 IBR domain Zn_Tnp_IS1595 PF12760.2 AIO02521.1 - 0.0081 15.9 1.9 0.012 15.3 1.3 1.4 1 0 0 1 1 1 1 Transposase zinc-ribbon domain FYVE_2 PF02318.11 AIO02521.1 - 0.012 15.4 1.3 0.015 15.2 0.9 1.1 1 0 0 1 1 1 0 FYVE-type zinc finger Cbl_N3 PF02762.9 AIO02521.1 - 0.06 12.9 0.0 0.07 12.7 0.0 1.2 1 0 0 1 1 1 0 CBL proto-oncogene N-terminus, SH2-like domain HypA PF01155.14 AIO02521.1 - 0.099 12.3 1.3 0.12 12.0 0.9 1.2 1 0 0 1 1 1 0 Hydrogenase expression/synthesis hypA family zinc_ribbon_4 PF13717.1 AIO02521.1 - 0.22 11.2 4.4 4.6 7.0 3.0 2.3 1 1 0 1 1 1 0 zinc-ribbon domain Elf1 PF05129.8 AIO02521.1 - 0.3 10.8 2.8 0.44 10.2 1.9 1.2 1 0 0 1 1 1 0 Transcription elongation factor Elf1 like zinc_ribbon_5 PF13719.1 AIO02521.1 - 0.4 10.3 4.6 6.6 6.4 3.2 2.3 1 1 0 1 1 1 0 zinc-ribbon domain Mu-like_Com PF10122.4 AIO02521.1 - 0.53 9.3 7.0 0.38 9.8 0.1 2.3 1 1 1 2 2 2 0 Mu-like prophage protein Com Zn_Tnp_IS1 PF03811.8 AIO02521.1 - 0.54 9.7 7.8 2.2 7.8 5.4 2.0 1 1 0 1 1 1 0 InsA N-terminal domain Ribosomal_L1 PF00687.16 AIO02522.1 - 5.9e-47 159.8 3.0 7e-47 159.5 2.1 1.0 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family NAC PF01849.13 AIO02523.1 - 2.8e-19 68.3 0.0 3.7e-19 67.9 0.0 1.2 1 0 0 1 1 1 1 NAC domain MORN PF02493.15 AIO02524.1 - 4.2e-15 54.4 58.4 4.9e-05 22.8 0.8 9.5 10 0 0 10 10 10 7 MORN repeat DUF448 PF04296.8 AIO02524.1 - 0.0026 17.3 0.2 3.4 7.3 0.0 3.6 3 0 0 3 3 3 1 Protein of unknown function (DUF448) DUF4078 PF13300.1 AIO02524.1 - 1.7 8.7 8.1 10 6.3 0.1 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4078) CH PF00307.26 AIO02525.1 - 0.0002 21.3 0.0 0.00055 19.9 0.0 1.8 1 0 0 1 1 1 1 Calponin homology (CH) domain CAMSAP_CH PF11971.3 AIO02525.1 - 0.079 12.6 0.0 0.23 11.1 0.0 1.7 1 0 0 1 1 1 0 CAMSAP CH domain GCV_T PF01571.16 AIO02526.1 - 2.7e-60 203.3 0.2 3.5e-60 202.9 0.1 1.1 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.6 AIO02526.1 - 4.5e-21 74.6 0.2 1.1e-20 73.3 0.1 1.7 1 0 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain Gly_reductase PF09338.6 AIO02526.1 - 0.0097 14.1 0.0 0.015 13.5 0.0 1.2 1 0 0 1 1 1 1 Glycine/sarcosine/betaine reductase component B subunits FTZ PF03867.9 AIO02526.1 - 0.078 12.2 0.0 0.12 11.5 0.0 1.3 1 0 0 1 1 1 0 Fushi tarazu (FTZ), N-terminal region SoxG PF04268.7 AIO02526.1 - 0.096 12.5 0.0 9.2 6.1 0.0 3.0 2 1 1 3 3 3 0 Sarcosine oxidase, gamma subunit family Gon7 PF08738.5 AIO02527.1 - 0.046 13.6 0.3 0.91 9.5 0.1 2.1 2 0 0 2 2 2 0 Gon7 family HisKA_3 PF07730.8 AIO02527.1 - 0.055 13.8 1.1 0.11 12.8 0.8 1.5 1 0 0 1 1 1 0 Histidine kinase DUF1664 PF07889.7 AIO02527.1 - 0.098 12.4 1.4 0.16 11.7 0.9 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) bZIP_2 PF07716.10 AIO02527.1 - 0.42 10.4 9.1 0.3 10.9 2.3 2.3 2 0 0 2 2 2 0 Basic region leucine zipper zf-C3HC4_3 PF13920.1 AIO02528.1 - 9.8e-17 60.3 36.7 5.9e-12 45.0 11.0 4.8 4 2 1 5 5 5 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 AIO02528.1 - 4.6e-06 26.5 36.9 0.00044 20.2 7.3 4.6 4 1 1 5 5 5 3 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 AIO02528.1 - 0.0017 18.0 45.5 0.0023 17.6 11.4 4.0 4 0 0 4 4 4 2 zinc-RING finger domain tRNA-synt_2b PF00587.20 AIO02529.1 - 5.2e-55 185.6 0.1 7.5e-55 185.1 0.1 1.2 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 AIO02529.1 - 2.6e-17 62.5 0.0 5e-17 61.6 0.0 1.5 1 0 0 1 1 1 1 Anticodon binding domain Snf7 PF03357.16 AIO02530.1 - 4.9e-32 110.6 25.7 4.9e-32 110.6 17.8 1.4 1 1 0 1 1 1 1 Snf7 Fic_N PF13784.1 AIO02530.1 - 0.021 14.6 3.1 0.028 14.2 0.1 2.4 2 1 0 2 2 2 0 Fic/DOC family N-terminal TraF_2 PF13729.1 AIO02530.1 - 0.057 12.2 5.3 0.22 10.2 0.7 2.1 1 1 1 2 2 2 0 F plasmid transfer operon, TraF, protein ODR4-like PF14778.1 AIO02530.1 - 0.22 10.1 4.3 0.48 9.0 3.1 1.5 1 1 0 1 1 1 0 Olfactory receptor 4-like DUF4558 PF15104.1 AIO02530.1 - 1.6 8.6 11.8 0.063 13.2 2.4 2.4 2 1 1 3 3 3 0 Domain of unknown function (DUF4558) Exonuc_VII_L PF02601.10 AIO02530.1 - 1.7 7.7 10.7 2 7.5 7.4 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit Atg14 PF10186.4 AIO02530.1 - 2.6 6.8 11.9 3.7 6.3 8.2 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 HAP2-GCS1 PF10699.4 AIO02531.1 - 2.9e-17 62.3 0.1 6.2e-17 61.3 0.1 1.6 1 0 0 1 1 1 1 Male gamete fusion factor LRR_6 PF13516.1 AIO02532.1 - 0.00086 19.1 0.0 0.051 13.6 0.0 3.4 3 0 0 3 3 3 1 Leucine Rich repeat Gasdermin PF04598.7 AIO02532.1 - 0.0011 17.7 0.6 0.0017 17.1 0.4 1.2 1 0 0 1 1 1 1 Gasdermin family LRR_4 PF12799.2 AIO02532.1 - 0.17 11.5 0.0 25 4.6 0.0 3.0 3 0 0 3 3 3 0 Leucine Rich repeats (2 copies) WD40 PF00400.27 AIO02533.1 - 1.1e-19 69.4 1.1 1.5e-07 31.0 0.0 5.9 6 0 0 6 6 6 4 WD domain, G-beta repeat Lactonase PF10282.4 AIO02533.1 - 0.037 13.1 0.1 0.18 10.8 0.0 2.1 2 0 0 2 2 2 0 Lactonase, 7-bladed beta-propeller DUF982 PF06169.7 AIO02535.1 - 0.012 15.3 0.4 0.05 13.3 0.2 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF982) AdoHcyase PF05221.12 AIO02536.1 - 1.3e-142 473.5 0.0 1.5e-142 473.3 0.0 1.0 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase AdoHcyase_NAD PF00670.16 AIO02536.1 - 8.9e-86 285.7 2.4 1.3e-85 285.2 1.7 1.2 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 2-Hacid_dh_C PF02826.14 AIO02536.1 - 9.5e-10 37.9 0.0 1.9e-09 36.9 0.0 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain TrkA_N PF02254.13 AIO02536.1 - 4.9e-05 23.2 0.3 0.00021 21.2 0.1 2.2 2 1 0 2 2 2 1 TrkA-N domain IlvN PF07991.7 AIO02536.1 - 5e-05 22.7 0.0 8.8e-05 21.9 0.0 1.4 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain NAD_binding_7 PF13241.1 AIO02536.1 - 0.00025 21.2 0.1 0.00059 20.0 0.1 1.6 1 0 0 1 1 1 1 Putative NAD(P)-binding ELFV_dehydrog PF00208.16 AIO02536.1 - 0.0062 16.1 0.1 0.012 15.2 0.0 1.5 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Oxidored_nitro PF00148.14 AIO02536.1 - 0.048 12.2 0.1 0.12 10.9 0.0 1.6 1 1 1 2 2 2 0 Nitrogenase component 1 type Oxidoreductase DUF4448 PF14610.1 AIO02536.1 - 0.096 12.1 0.0 0.14 11.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) UDPG_MGDP_dh_N PF03721.9 AIO02536.1 - 0.1 11.9 0.3 0.17 11.2 0.2 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain TcpE PF12648.2 AIO02537.1 - 0.13 12.4 0.6 0.71 10.0 0.5 2.1 1 1 1 2 2 2 0 TcpE family Telomerase_RBD PF12009.3 AIO02538.1 - 9.3e-31 106.5 0.1 1.6e-30 105.7 0.0 1.4 1 0 0 1 1 1 1 Telomerase ribonucleoprotein complex - RNA binding domain RVT_1 PF00078.22 AIO02538.1 - 0.00011 21.6 0.0 0.00032 20.1 0.0 1.8 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) AAA_11 PF13086.1 AIO02540.1 - 0.0073 15.8 4.0 0.0096 15.5 2.8 1.2 1 0 0 1 1 1 1 AAA domain GSCFA PF08885.6 AIO02540.1 - 0.0075 15.8 0.6 0.012 15.2 0.3 1.5 1 1 0 1 1 1 1 GSCFA family Prefoldin PF02996.12 AIO02540.1 - 0.015 14.9 4.1 3.3 7.3 0.0 3.3 3 0 0 3 3 3 0 Prefoldin subunit Bacillus_HBL PF05791.6 AIO02540.1 - 0.027 13.8 5.6 0.047 13.0 0.2 2.6 2 1 0 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) OmpH PF03938.9 AIO02540.1 - 0.072 13.0 0.6 0.072 13.0 0.4 2.3 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) AAA_13 PF13166.1 AIO02540.1 - 0.073 11.5 7.2 0.11 10.9 5.0 1.2 1 0 0 1 1 1 0 AAA domain IFT57 PF10498.4 AIO02540.1 - 0.088 11.5 9.4 0.23 10.1 6.5 1.7 1 1 0 1 1 1 0 Intra-flagellar transport protein 57 BcrAD_BadFG PF01869.15 AIO02540.1 - 0.14 11.4 1.8 1.6 7.9 0.1 2.1 1 1 1 2 2 2 0 BadF/BadG/BcrA/BcrD ATPase family FliD_C PF07195.7 AIO02540.1 - 0.17 11.1 3.2 0.2 10.9 0.2 2.0 2 0 0 2 2 2 0 Flagellar hook-associated protein 2 C-terminus Atg14 PF10186.4 AIO02540.1 - 0.36 9.7 15.5 0.89 8.4 4.9 2.4 1 1 2 3 3 3 0 UV radiation resistance protein and autophagy-related subunit 14 TACC PF05010.9 AIO02540.1 - 0.49 10.1 10.6 2.4 7.8 6.9 2.1 1 1 1 2 2 2 0 Transforming acidic coiled-coil-containing protein (TACC) MADF_DNA_bdg PF10545.4 AIO02540.1 - 0.58 10.3 3.3 7.5 6.8 0.2 2.9 1 1 0 2 2 2 0 Alcohol dehydrogenase transcription factor Myb/SANT-like Baculo_p24 PF05073.7 AIO02540.1 - 1 8.9 5.7 2.7 7.5 0.8 2.2 2 0 0 2 2 2 0 Baculovirus P24 capsid protein ISG65-75 PF11727.3 AIO02540.1 - 2.4 7.1 8.9 11 4.9 0.1 2.3 1 1 1 2 2 2 0 Invariant surface glycoprotein TPR_MLP1_2 PF07926.7 AIO02540.1 - 4.5 7.0 11.6 1.2 8.8 1.3 2.6 3 0 0 3 3 3 0 TPR/MLP1/MLP2-like protein XdhC_CoxI PF02625.11 AIO02541.1 - 0.18 11.4 4.0 1.5 8.4 0.1 3.2 3 0 0 3 3 3 0 XdhC and CoxI family CDC73 PF05179.9 AIO02543.1 - 2.5e-26 92.6 0.0 3.5e-26 92.1 0.0 1.3 1 0 0 1 1 1 1 RNA pol II accessory factor, Cdc73 family Proteasome PF00227.21 AIO02544.1 - 6.3e-26 90.8 0.3 1.2e-25 89.9 0.2 1.4 1 1 0 1 1 1 1 Proteasome subunit Rieske PF00355.21 AIO02545.1 - 0.075 12.6 0.0 0.12 11.9 0.0 1.4 1 0 0 1 1 1 0 Rieske [2Fe-2S] domain Rabaptin PF03528.10 AIO02546.1 - 0.27 11.1 5.6 1.5 8.7 0.1 2.8 3 0 0 3 3 3 0 Rabaptin V-SNARE_C PF12352.3 AIO02547.1 - 3.7e-07 30.1 1.3 3.7e-07 30.1 0.9 1.9 2 0 0 2 2 2 1 Snare region anchored in the vesicle membrane C-terminus RD3 PF14473.1 AIO02547.1 - 0.049 13.1 0.7 0.17 11.3 0.0 2.2 2 0 0 2 2 2 0 RD3 protein Sec20 PF03908.8 AIO02547.1 - 0.094 12.4 0.3 0.44 10.2 0.1 2.1 2 0 0 2 2 2 0 Sec20 Acetyltransf_9 PF13527.1 AIO02547.1 - 0.1 12.4 0.0 0.26 11.1 0.0 1.7 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain DUF370 PF04025.7 AIO02547.1 - 0.11 12.5 0.0 0.24 11.4 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF370) Peptidase_M14 PF00246.19 AIO02548.1 - 3.6e-25 89.1 0.0 9.3e-25 87.7 0.0 1.6 1 1 0 1 1 1 1 Zinc carboxypeptidase AstE_AspA PF04952.9 AIO02548.1 - 3.1e-07 29.5 0.1 4.9e-07 28.9 0.1 1.3 1 0 0 1 1 1 1 Succinylglutamate desuccinylase / Aspartoacylase family Gp_dh_C PF02800.15 AIO02548.1 - 0.098 12.1 0.2 0.38 10.1 0.0 2.0 2 0 0 2 2 2 0 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain TPR_12 PF13424.1 AIO02549.1 - 5.5e-06 26.2 5.9 0.68 9.9 0.0 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.12 AIO02549.1 - 1.4e-05 24.5 4.3 1.2 9.2 0.0 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.1 AIO02549.1 - 2.2e-05 23.9 3.3 0.011 15.4 0.2 2.8 2 1 0 2 2 2 2 TPR repeat TPR_16 PF13432.1 AIO02549.1 - 0.00042 20.9 7.5 0.076 13.7 1.0 3.6 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.23 AIO02549.1 - 0.0023 17.4 1.4 1.6 8.5 0.0 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.1 AIO02549.1 - 0.004 16.8 5.2 0.58 10.0 0.0 3.6 4 0 0 4 4 4 2 Tetratricopeptide repeat SHNi-TPR PF10516.4 AIO02549.1 - 0.013 14.7 0.3 0.03 13.5 0.2 1.6 1 0 0 1 1 1 0 SHNi-TPR TPR_19 PF14559.1 AIO02549.1 - 0.025 14.9 3.7 1.1 9.6 0.0 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.1 AIO02549.1 - 0.045 13.5 0.6 9.1 6.3 0.0 2.8 3 0 0 3 3 2 0 Tetratricopeptide repeat TPR_14 PF13428.1 AIO02549.1 - 0.16 12.7 6.0 3.7 8.4 0.1 3.9 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.1 AIO02549.1 - 0.22 12.0 1.8 6.3 7.4 0.0 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF2201_N PF13203.1 AIO02549.1 - 1 8.4 9.3 1.9 7.5 6.4 1.4 1 0 0 1 1 1 0 Putative metallopeptidase domain CDC45 PF02724.9 AIO02549.1 - 1.7 6.5 8.9 2.4 6.0 6.2 1.1 1 0 0 1 1 1 0 CDC45-like protein Spore_coat_CotO PF14153.1 AIO02549.1 - 2.9 7.3 9.1 7.5 5.9 6.3 1.7 1 0 0 1 1 1 0 Spore coat protein CotO RCC1 PF00415.13 AIO02550.1 - 1.6e-37 127.4 13.0 4.5e-10 39.5 0.1 7.8 7 1 0 7 7 7 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 AIO02550.1 - 9.8e-20 69.6 21.4 1e-05 24.9 2.3 6.8 6 1 0 6 6 6 5 Regulator of chromosome condensation (RCC1) repeat ProSAAS PF07259.7 AIO02550.1 - 0.00064 19.3 1.4 0.0014 18.1 0.9 1.6 1 0 0 1 1 1 1 ProSAAS precursor His_Phos_1 PF00300.17 AIO02551.1 - 2.4e-14 53.7 4.0 1.1e-12 48.3 2.8 2.4 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) DUF4398 PF14346.1 AIO02551.1 - 0.053 13.5 2.0 0.12 12.4 1.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4398) IQ PF00612.22 AIO02552.1 - 1.9e-12 45.6 8.9 0.0032 16.9 0.1 3.9 3 0 0 3 3 3 3 IQ calmodulin-binding motif Glyco_hydro_31 PF01055.21 AIO02554.1 - 7.2e-45 153.6 0.0 2.5e-31 108.9 0.0 2.8 2 1 0 2 2 2 2 Glycosyl hydrolases family 31 DUF2660 PF10859.3 AIO02555.1 - 0.056 13.6 0.0 0.12 12.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2660) Amastin PF07344.6 AIO02557.1 - 3.3e-07 30.0 5.4 4.1e-07 29.7 3.8 1.1 1 0 0 1 1 1 1 Amastin surface glycoprotein DUF4191 PF13829.1 AIO02557.1 - 0.41 9.7 1.4 0.45 9.5 1.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4191) DUF2207 PF09972.4 AIO02557.1 - 0.76 8.2 3.7 0.91 8.0 2.6 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) MpPF26 PF07666.6 AIO02557.1 - 1.4 8.7 11.4 0.23 11.3 1.9 2.1 1 1 1 2 2 2 0 M penetrans paralogue family 26 Amastin PF07344.6 AIO02558.1 - 9.6e-15 54.5 6.6 2e-14 53.4 4.5 1.5 1 1 0 1 1 1 1 Amastin surface glycoprotein Claudin_2 PF13903.1 AIO02558.1 - 3.6 7.2 14.3 3 7.5 7.7 2.1 1 1 1 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction TFIIS_C PF01096.13 AIO02559.1 - 1.8e-11 43.4 7.5 1.8e-11 43.4 5.2 2.7 2 1 0 2 2 2 1 Transcription factor S-II (TFIIS) DUF1451 PF07295.6 AIO02559.1 - 0.00092 19.0 0.2 0.00092 19.0 0.1 2.2 3 0 0 3 3 3 1 Protein of unknown function (DUF1451) C1_1 PF00130.17 AIO02559.1 - 0.032 13.9 0.5 0.032 13.9 0.4 2.7 2 1 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Rpr2 PF04032.11 AIO02559.1 - 0.2 11.5 5.2 3.5 7.5 0.5 2.7 2 1 0 2 2 2 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain DUF678 PF05077.7 AIO02559.1 - 0.3 11.1 4.5 34 4.5 2.1 3.2 2 1 0 2 2 2 0 Protein of unknown function (DUF678) Sp38 PF07354.7 AIO02559.1 - 0.3 9.6 4.0 0.54 8.8 0.8 2.0 2 0 0 2 2 2 0 Zona-pellucida-binding protein (Sp38) eIF-5_eIF-2B PF01873.12 AIO02559.1 - 2.5 7.7 6.0 3.8 7.1 1.5 2.7 2 2 1 3 3 3 0 Domain found in IF2B/IF5 zf-ribbon_3 PF13248.1 AIO02559.1 - 3.9 6.8 12.2 25 4.2 0.0 4.7 5 0 0 5 5 5 0 zinc-ribbon domain GFA PF04828.9 AIO02559.1 - 7.8 6.5 11.3 3.9 7.4 0.2 3.3 2 2 1 3 3 3 0 Glutathione-dependent formaldehyde-activating enzyme ZF-HD_dimer PF04770.7 AIO02559.1 - 8.2 6.5 8.1 33 4.6 0.5 3.3 2 1 1 3 3 3 0 ZF-HD protein dimerisation region Baculo_LEF5_C PF11792.3 AIO02559.1 - 9.2 5.7 10.1 0.72 9.2 3.0 2.2 2 1 0 2 2 2 0 Baculoviridae late expression factor 5 C-terminal domain DZR PF12773.2 AIO02559.1 - 9.7 6.1 16.2 7.3 6.4 1.7 3.4 2 2 0 2 2 2 0 Double zinc ribbon ADH_zinc_N PF00107.21 AIO02562.1 - 3.3e-32 110.7 0.0 8.7e-32 109.4 0.0 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 AIO02562.1 - 8e-15 54.5 1.2 1.1e-14 54.1 0.1 1.8 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 AIO02562.1 - 3.5e-13 50.5 0.0 1e-12 49.0 0.0 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Semialdhyde_dh PF01118.19 AIO02562.1 - 0.018 15.3 0.0 0.26 11.6 0.0 2.2 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain Gly_rich_SFCGS PF14272.1 AIO02562.1 - 0.03 14.2 0.4 3.3 7.5 0.1 2.4 2 0 0 2 2 2 0 Glycine-rich SFCGS TrkA_N PF02254.13 AIO02562.1 - 0.086 12.8 0.0 0.17 11.9 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain Glycos_transf_4 PF00953.16 AIO02563.1 - 2.3e-43 147.7 6.0 2.3e-43 147.7 4.2 2.2 2 0 0 2 2 2 1 Glycosyl transferase family 4 DUF2929 PF11151.3 AIO02563.1 - 3.1 7.9 6.9 0.85 9.7 0.1 3.3 4 0 0 4 4 4 0 Protein of unknown function (DUF2929) Sld5 PF05916.6 AIO02564.1 - 1.1e-22 80.3 0.0 1.7e-22 79.7 0.0 1.3 1 0 0 1 1 1 1 GINS complex protein LDB19 PF13002.2 AIO02565.1 - 1.4e-05 24.6 0.1 8.6e-05 22.1 0.0 2.3 3 0 0 3 3 3 1 Arrestin_N terminal like Arrestin_N PF00339.24 AIO02565.1 - 0.00019 21.2 4.7 0.00071 19.4 0.0 3.5 5 0 0 5 5 5 1 Arrestin (or S-antigen), N-terminal domain WD40 PF00400.27 AIO02566.1 - 1.4e-22 78.6 7.1 2.7e-07 30.2 0.0 8.4 9 0 0 9 9 9 3 WD domain, G-beta repeat Utp21 PF04192.7 AIO02566.1 - 2.9e-19 69.1 0.0 4.5e-19 68.5 0.0 1.2 1 0 0 1 1 1 1 Utp21 specific WD40 associated putative domain Nup160 PF11715.3 AIO02566.1 - 0.00013 20.2 3.1 0.078 11.1 0.0 4.5 4 1 0 4 4 4 1 Nucleoporin Nup120/160 PQQ_2 PF13360.1 AIO02566.1 - 0.0029 17.0 5.7 0.22 10.9 0.9 3.1 2 2 0 2 2 2 2 PQQ-like domain DUF1484 PF07363.6 AIO02566.1 - 0.042 14.2 0.2 0.31 11.4 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1484) Utp12 PF04003.7 AIO02566.1 - 0.058 13.3 0.1 0.13 12.1 0.0 1.5 1 0 0 1 1 1 0 Dip2/Utp12 Family LRR_6 PF13516.1 AIO02568.1 - 7.2e-36 118.2 54.4 0.0031 17.4 0.1 21.3 24 0 0 24 24 24 11 Leucine Rich repeat LRR_4 PF12799.2 AIO02568.1 - 1.5e-20 72.3 44.7 0.012 15.2 0.0 14.1 9 4 7 17 17 17 12 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 AIO02568.1 - 3.5e-09 35.4 36.0 21 5.6 0.0 17.8 20 1 0 20 20 20 3 Leucine Rich Repeat LRR_8 PF13855.1 AIO02568.1 - 6.1e-08 32.3 46.0 0.059 13.1 0.1 12.7 10 4 3 13 13 13 6 Leucine rich repeat WD40 PF00400.27 AIO02569.1 - 2.2e-10 39.9 10.5 9.5e-05 22.1 0.0 6.2 7 0 0 7 7 7 3 WD domain, G-beta repeat Pkinase PF00069.20 AIO02570.1 - 5.5e-46 156.8 0.0 1.3e-21 76.9 0.0 2.7 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 AIO02570.1 - 3.7e-16 58.9 0.0 1.8e-09 37.0 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase TPR_14 PF13428.1 AIO02573.1 - 1.3e-12 47.1 43.6 0.039 14.6 0.1 12.2 10 4 3 13 13 13 7 Tetratricopeptide repeat TPR_19 PF14559.1 AIO02573.1 - 3.2e-11 43.4 5.2 0.001 19.3 0.0 5.7 6 0 0 6 6 5 2 Tetratricopeptide repeat HAT PF02184.11 AIO02573.1 - 1.6e-08 34.1 10.2 0.1 12.3 0.1 5.6 5 0 0 5 5 5 3 HAT (Half-A-TPR) repeat TPR_16 PF13432.1 AIO02573.1 - 1.6e-06 28.6 32.1 0.17 12.5 0.7 8.5 7 1 1 8 8 8 4 Tetratricopeptide repeat NRDE-2 PF08424.5 AIO02573.1 - 0.0012 17.7 0.8 0.046 12.5 0.1 3.2 2 1 0 2 2 2 1 NRDE-2, necessary for RNA interference TPR_12 PF13424.1 AIO02573.1 - 0.0012 18.6 14.9 1.9 8.4 0.2 6.3 4 2 3 7 7 7 3 Tetratricopeptide repeat TPR_9 PF13371.1 AIO02573.1 - 0.02 14.7 0.1 0.02 14.7 0.1 5.3 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_2 PF07719.12 AIO02573.1 - 0.054 13.4 11.4 28 4.9 0.0 7.0 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_17 PF13431.1 AIO02573.1 - 0.48 10.7 6.3 28 5.2 0.0 5.6 7 0 0 7 7 6 0 Tetratricopeptide repeat TPR_6 PF13174.1 AIO02573.1 - 0.52 10.8 15.3 20 5.9 0.2 7.4 8 0 0 8 8 7 0 Tetratricopeptide repeat TPR_7 PF13176.1 AIO02573.1 - 1.3 9.0 17.5 2.2 8.2 0.0 7.0 8 0 0 8 8 8 0 Tetratricopeptide repeat Arf PF00025.16 AIO02574.1 - 2.6e-12 46.3 0.0 4.7e-12 45.4 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family PH PF00169.24 AIO02574.1 - 1.4e-05 25.2 0.0 4.1e-05 23.7 0.0 1.8 1 0 0 1 1 1 1 PH domain MMR_HSR1 PF01926.18 AIO02574.1 - 0.0055 16.6 0.0 0.019 14.9 0.0 2.0 1 0 0 1 1 1 1 50S ribosome-binding GTPase PH_8 PF15409.1 AIO02574.1 - 0.014 15.4 0.1 0.072 13.1 0.1 2.3 2 0 0 2 2 2 0 Pleckstrin homology domain Gtr1_RagA PF04670.7 AIO02574.1 - 0.12 11.4 0.0 0.29 10.2 0.0 1.6 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region PH_11 PF15413.1 AIO02574.1 - 0.14 12.4 0.2 0.36 11.1 0.1 1.7 1 0 0 1 1 1 0 Pleckstrin homology domain C2 PF00168.25 AIO02575.1 - 1.5e-28 98.4 0.0 5.3e-09 35.8 0.0 5.5 5 0 0 5 5 5 3 C2 domain CEP76-C2 PF15627.1 AIO02575.1 - 0.41 10.1 2.2 14 5.1 0.0 3.4 4 0 0 4 4 4 0 CEP76 C2 domain C2 PF00168.25 AIO02576.1 - 9.1e-06 25.4 0.0 2.3 8.1 0.0 4.4 4 0 0 4 4 4 3 C2 domain AAA PF00004.24 AIO02579.1 - 4.8e-44 149.7 0.0 1e-43 148.6 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 AIO02579.1 - 6e-08 32.5 0.1 2.1e-07 30.7 0.1 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 AIO02579.1 - 3e-07 30.4 0.4 2.4e-06 27.5 0.0 2.5 3 0 0 3 3 3 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.1 AIO02579.1 - 4e-07 30.2 0.4 1e-05 25.6 0.0 2.7 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 AIO02579.1 - 3.5e-06 27.1 1.5 0.00029 20.9 0.2 3.2 2 1 0 2 2 2 1 AAA domain RuvB_N PF05496.7 AIO02579.1 - 2.2e-05 23.6 0.0 5.2e-05 22.3 0.0 1.7 2 0 0 2 2 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 AIO02579.1 - 6.1e-05 22.6 1.1 0.00035 20.2 0.2 2.6 2 1 0 2 2 2 1 Part of AAA domain AAA_14 PF13173.1 AIO02579.1 - 7.8e-05 22.5 0.0 0.0022 17.9 0.0 2.3 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.12 AIO02579.1 - 0.00016 21.1 0.0 0.00043 19.7 0.0 1.7 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_17 PF13207.1 AIO02579.1 - 0.00017 22.3 0.1 0.00072 20.3 0.1 2.1 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 AIO02579.1 - 0.0013 18.6 0.1 0.0035 17.2 0.0 1.8 2 0 0 2 2 1 1 AAA domain NB-ARC PF00931.17 AIO02579.1 - 0.0017 17.2 0.0 0.039 12.7 0.0 2.4 1 1 1 2 2 2 1 NB-ARC domain AAA_25 PF13481.1 AIO02579.1 - 0.0018 17.6 1.2 0.16 11.3 0.0 2.9 2 1 1 3 3 3 1 AAA domain KaiC PF06745.8 AIO02579.1 - 0.0019 17.3 0.2 0.084 11.9 0.0 2.6 3 0 0 3 3 3 1 KaiC Zeta_toxin PF06414.7 AIO02579.1 - 0.0021 17.2 0.1 0.0056 15.8 0.0 1.8 2 0 0 2 2 2 1 Zeta toxin Sigma54_activat PF00158.21 AIO02579.1 - 0.0022 17.4 0.7 0.048 13.1 0.1 3.2 2 1 0 2 2 2 1 Sigma-54 interaction domain AAA_28 PF13521.1 AIO02579.1 - 0.0028 17.6 0.3 0.0063 16.4 0.0 1.7 2 0 0 2 2 1 1 AAA domain TIP49 PF06068.8 AIO02579.1 - 0.0035 16.1 0.0 0.013 14.1 0.0 1.9 2 0 0 2 2 2 1 TIP49 C-terminus AAA_18 PF13238.1 AIO02579.1 - 0.0047 17.2 0.2 0.023 14.9 0.0 2.2 2 1 0 2 2 2 1 AAA domain Sigma54_activ_2 PF14532.1 AIO02579.1 - 0.0053 16.8 0.2 0.094 12.7 0.0 2.9 3 1 0 3 3 2 1 Sigma-54 interaction domain Mg_chelatase PF01078.16 AIO02579.1 - 0.0064 15.6 0.0 0.023 13.8 0.0 1.9 2 0 0 2 2 1 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.6 AIO02579.1 - 0.0076 15.8 0.0 0.018 14.6 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.1 AIO02579.1 - 0.0096 15.5 0.1 0.034 13.7 0.0 1.9 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.17 AIO02579.1 - 0.0099 16.0 0.0 0.022 14.9 0.0 1.6 1 0 0 1 1 1 1 RNA helicase DUF815 PF05673.8 AIO02579.1 - 0.013 14.4 0.2 0.034 13.0 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF815) PhoH PF02562.11 AIO02579.1 - 0.016 14.4 0.1 0.057 12.6 0.0 2.0 2 0 0 2 2 2 0 PhoH-like protein ADIP PF11559.3 AIO02579.1 - 0.024 14.5 1.3 0.045 13.6 0.9 1.4 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding DASH_Dad2 PF08654.5 AIO02579.1 - 0.029 14.3 0.6 0.081 12.9 0.4 1.7 1 0 0 1 1 1 0 DASH complex subunit Dad2 NACHT PF05729.7 AIO02579.1 - 0.039 13.6 0.0 0.56 9.8 0.0 2.4 1 1 1 2 2 2 0 NACHT domain Parvo_NS1 PF01057.12 AIO02579.1 - 0.048 12.5 0.0 0.087 11.6 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_11 PF13086.1 AIO02579.1 - 0.059 12.9 0.2 0.35 10.3 0.0 2.2 2 1 0 2 2 2 0 AAA domain DUF2968 PF11180.3 AIO02579.1 - 0.13 11.6 2.0 0.27 10.5 1.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) HECT PF00632.20 AIO02580.1 - 4.2e-66 223.2 0.0 5.6e-65 219.5 0.0 2.2 2 0 0 2 2 2 1 HECT-domain (ubiquitin-transferase) AOX PF01786.12 AIO02581.1 - 3.4e-88 294.4 0.0 4.3e-88 294.1 0.0 1.1 1 0 0 1 1 1 1 Alternative oxidase Spc97_Spc98 PF04130.8 AIO02582.1 - 1.7e-86 290.6 0.0 2.2e-86 290.3 0.0 1.1 1 0 0 1 1 1 1 Spc97 / Spc98 family DUF309 PF03745.9 AIO02582.1 - 0.01 15.2 0.3 0.048 13.1 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF309) DEAD PF00270.24 AIO02583.1 - 1.7e-33 115.5 0.1 5.8e-33 113.7 0.0 2.0 3 0 0 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.26 AIO02583.1 - 7.1e-24 83.4 0.1 2.6e-23 81.6 0.1 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 AIO02583.1 - 0.015 15.1 0.0 0.044 13.6 0.0 1.9 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit UvrD-helicase PF00580.16 AIO02583.1 - 0.11 11.8 0.0 0.11 11.8 0.0 2.2 3 0 0 3 3 3 0 UvrD/REP helicase N-terminal domain AAA_22 PF13401.1 AIO02583.1 - 0.12 12.5 1.6 38 4.4 0.0 3.9 4 1 1 5 5 5 0 AAA domain Ribosomal_L22e PF01776.12 AIO02585.1 - 9.9e-40 135.0 3.4 1.2e-39 134.7 2.4 1.1 1 0 0 1 1 1 1 Ribosomal L22e protein family Asparaginase PF00710.15 AIO02586.1 - 1.4e-64 217.9 0.0 1.7e-64 217.7 0.0 1.0 1 0 0 1 1 1 1 Asparaginase TPR_17 PF13431.1 AIO02587.1 - 4.4e-05 23.3 6.5 0.0046 17.0 0.3 4.2 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_11 PF13414.1 AIO02587.1 - 0.00022 20.8 0.3 0.0088 15.6 0.2 3.0 3 0 0 3 3 3 1 TPR repeat TPR_19 PF14559.1 AIO02587.1 - 0.00032 20.9 0.1 0.096 13.0 0.0 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.1 AIO02587.1 - 0.001 19.7 0.9 0.076 13.7 0.1 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.1 AIO02587.1 - 0.0012 19.2 1.4 0.32 11.7 0.3 3.3 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.12 AIO02587.1 - 0.0024 17.6 0.1 0.0024 17.6 0.1 2.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.1 AIO02587.1 - 0.0058 16.5 0.1 0.066 13.1 0.0 2.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.23 AIO02587.1 - 0.027 14.0 1.4 0.09 12.4 0.2 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat Apc3 PF12895.2 AIO02587.1 - 0.033 14.3 1.2 0.3 11.2 0.1 2.7 2 1 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_4 PF07721.9 AIO02587.1 - 0.038 14.4 1.5 0.09 13.2 0.4 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat Peptidase_M3 PF01432.15 AIO02588.1 - 7e-70 236.3 0.1 1.1e-55 189.5 0.1 2.0 2 0 0 2 2 2 2 Peptidase family M3 DnaJ PF00226.26 AIO02590.1 - 1.2e-22 79.3 0.7 2.8e-22 78.1 0.1 2.0 2 0 0 2 2 2 1 DnaJ domain FCH PF00611.18 AIO02590.1 - 2.5 8.3 6.3 7.6 6.7 2.7 2.6 2 0 0 2 2 2 0 Fes/CIP4, and EFC/F-BAR homology domain Aa_trans PF01490.13 AIO02591.1 - 9.4e-43 146.2 0.0 1.1e-35 123.0 0.0 2.4 2 1 0 2 2 2 2 Transmembrane amino acid transporter protein DUF2207 PF09972.4 AIO02591.1 - 1.4 7.4 4.2 1.5 7.3 0.0 2.6 3 0 0 3 3 3 0 Predicted membrane protein (DUF2207) Methyltransf_26 PF13659.1 AIO02592.1 - 1e-13 51.3 0.0 2.3e-13 50.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 AIO02592.1 - 1e-13 51.0 0.1 4.3e-11 42.4 0.0 2.2 1 1 1 2 2 2 2 Methyltransferase small domain Methyltransf_31 PF13847.1 AIO02592.1 - 1e-10 41.4 0.0 4.8e-10 39.2 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 AIO02592.1 - 6.1e-09 36.4 0.0 1.2e-08 35.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 AIO02592.1 - 5e-07 29.1 0.0 1.1e-06 27.9 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_25 PF13649.1 AIO02592.1 - 6.1e-05 23.3 0.0 0.00013 22.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 AIO02592.1 - 0.00027 20.1 0.0 0.00043 19.4 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_11 PF08241.7 AIO02592.1 - 0.00049 20.5 0.0 0.0011 19.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Met_10 PF02475.11 AIO02592.1 - 0.0031 17.1 0.0 0.0045 16.5 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein UPF0020 PF01170.13 AIO02592.1 - 0.0034 16.9 0.4 2.1 7.8 0.0 2.4 2 0 0 2 2 2 2 Putative RNA methylase family UPF0020 Methyltransf_23 PF13489.1 AIO02592.1 - 0.0059 16.3 0.0 0.049 13.3 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 AIO02592.1 - 0.0075 16.7 0.0 0.018 15.4 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.1 AIO02592.1 - 0.0081 15.8 0.0 0.015 14.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_16 PF10294.4 AIO02592.1 - 0.0088 15.5 0.0 0.014 14.8 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase TRM PF02005.11 AIO02592.1 - 0.045 12.6 0.0 0.06 12.2 0.0 1.1 1 0 0 1 1 1 0 N2,N2-dimethylguanosine tRNA methyltransferase Methyltransf_15 PF09445.5 AIO02592.1 - 0.045 13.3 0.0 0.086 12.3 0.0 1.4 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase FmrO PF07091.6 AIO02592.1 - 0.096 11.6 0.3 0.17 10.8 0.0 1.5 2 0 0 2 2 2 0 Ribosomal RNA methyltransferase (FmrO) DUF2870 PF11069.3 AIO02593.1 - 1.3e-37 127.7 0.0 2.7e-37 126.7 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2870) ETF PF01012.16 AIO02593.1 - 0.047 13.4 0.0 0.093 12.4 0.0 1.5 1 0 0 1 1 1 0 Electron transfer flavoprotein domain Ribosomal_L18e PF00828.14 AIO02594.1 - 5.8e-20 71.9 0.2 5.8e-20 71.9 0.1 1.5 2 0 0 2 2 2 1 Ribosomal protein L18e/L15 ABC1 PF03109.11 AIO02596.1 - 6.7e-25 87.3 0.0 1.3e-24 86.4 0.0 1.5 1 0 0 1 1 1 1 ABC1 family Alpha_kinase PF02816.13 AIO02597.1 - 4.2e-57 192.8 0.2 5.3e-57 192.5 0.1 1.1 1 0 0 1 1 1 1 Alpha-kinase family UIM PF02809.15 AIO02597.1 - 0.047 13.2 1.5 0.12 11.9 1.0 1.8 1 0 0 1 1 1 0 Ubiquitin interaction motif Alpha_kinase PF02816.13 AIO02598.1 - 6e-104 345.6 0.0 1e-43 149.2 0.0 3.2 3 0 0 3 3 3 3 Alpha-kinase family ERp29 PF07749.7 AIO02598.1 - 0.14 12.8 0.1 0.3 11.7 0.1 1.5 1 0 0 1 1 1 0 Endoplasmic reticulum protein ERp29, C-terminal domain Alpha_kinase PF02816.13 AIO02599.1 - 7e-67 224.7 0.8 8.3e-67 224.5 0.6 1.1 1 0 0 1 1 1 1 Alpha-kinase family PSP1 PF04468.7 AIO02600.1 - 4.9e-29 100.1 0.4 4.9e-29 100.1 0.3 1.8 2 0 0 2 2 2 1 PSP1 C-terminal conserved region DASH_Spc34 PF08657.5 AIO02600.1 - 0.025 14.2 0.2 0.044 13.4 0.1 1.3 1 0 0 1 1 1 0 DASH complex subunit Spc34 BBS2_N PF14781.1 AIO02602.1 - 0.068 12.8 0.0 8.4 6.0 0.0 2.5 2 0 0 2 2 2 0 Ciliary BBSome complex subunit 2, N-terminal zf-HC5HC2H PF13771.1 AIO02603.1 - 8.3e-09 35.4 4.9 8.3e-09 35.4 3.4 3.0 3 0 0 3 3 3 1 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.1 AIO02603.1 - 1e-07 31.9 6.2 1e-07 31.9 4.3 2.9 2 1 0 2 2 2 1 PHD-zinc-finger like domain SNARE PF05739.14 AIO02604.1 - 0.00011 21.8 0.3 0.00029 20.4 0.2 1.8 1 0 0 1 1 1 1 SNARE domain FliJ PF02050.11 AIO02604.1 - 2.7 8.0 13.8 1.3 9.1 0.1 2.5 2 0 0 2 2 2 0 Flagellar FliJ protein 3-PAP PF12578.3 AIO02605.1 - 0.034 14.0 0.0 0.11 12.3 0.0 1.9 1 0 0 1 1 1 0 Myotubularin-associated protein M3 PF09213.5 AIO02605.1 - 0.054 11.9 0.1 0.092 11.2 0.1 1.2 1 0 0 1 1 1 0 M3 Ham1p_like PF01725.11 AIO02606.1 - 4.3e-56 189.2 0.0 5e-56 189.0 0.0 1.0 1 0 0 1 1 1 1 Ham1 family Peptidase_S9 PF00326.16 AIO02607.1 - 3.3e-08 33.0 0.2 5.7e-07 28.9 0.0 2.5 2 1 1 3 3 3 1 Prolyl oligopeptidase family Abhydrolase_2 PF02230.11 AIO02607.1 - 5.4e-07 29.2 0.1 9e-06 25.2 0.0 2.4 2 1 0 2 2 2 1 Phospholipase/Carboxylesterase Esterase_phd PF10503.4 AIO02607.1 - 1.3e-06 27.8 1.8 7.4e-06 25.3 1.3 2.2 1 1 0 1 1 1 1 Esterase PHB depolymerase Abhydrolase_5 PF12695.2 AIO02607.1 - 2.1e-06 27.5 0.2 3.9e-06 26.6 0.1 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 AIO02607.1 - 0.00025 21.0 0.2 0.011 15.6 0.0 2.3 1 1 1 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 AIO02607.1 - 0.00073 19.1 0.0 0.058 12.9 0.0 2.2 1 1 0 2 2 2 1 alpha/beta hydrolase fold Esterase PF00756.15 AIO02607.1 - 0.0014 18.0 0.1 0.01 15.2 0.0 2.1 1 1 0 1 1 1 1 Putative esterase FSH1 PF03959.8 AIO02607.1 - 0.031 13.6 0.0 0.055 12.8 0.0 1.3 1 0 0 1 1 1 0 Serine hydrolase (FSH1) DUF1100 PF06500.6 AIO02607.1 - 0.033 12.7 0.0 0.05 12.1 0.0 1.1 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1100) Peptidase_S15 PF02129.13 AIO02607.1 - 0.064 12.6 0.1 0.57 9.5 0.0 2.4 1 1 1 2 2 2 0 X-Pro dipeptidyl-peptidase (S15 family) DLH PF01738.13 AIO02607.1 - 0.12 11.6 0.0 0.3 10.3 0.0 1.6 1 0 0 1 1 1 0 Dienelactone hydrolase family Ribosomal_L10 PF00466.15 AIO02608.1 - 6.5e-18 64.5 0.3 9.8e-18 63.9 0.2 1.2 1 0 0 1 1 1 1 Ribosomal protein L10 VPS9 PF02204.13 AIO02609.1 - 9.8e-29 99.4 0.0 2.4e-28 98.1 0.0 1.7 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain HALZ PF02183.13 AIO02610.1 - 0.0013 18.3 0.5 0.0013 18.3 0.4 2.1 2 0 0 2 2 2 1 Homeobox associated leucine zipper DUF904 PF06005.7 AIO02610.1 - 0.0047 17.1 2.4 0.0047 17.1 1.7 2.3 1 1 1 2 2 2 1 Protein of unknown function (DUF904) DUF2353 PF09789.4 AIO02610.1 - 0.007 15.6 1.5 0.0079 15.4 1.0 1.1 1 0 0 1 1 1 1 Uncharacterized coiled-coil protein (DUF2353) DUF4201 PF13870.1 AIO02610.1 - 0.02 14.3 7.0 0.12 11.7 5.2 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4201) Bac_luciferase PF00296.15 AIO02610.1 - 0.03 13.4 1.0 0.034 13.2 0.7 1.0 1 0 0 1 1 1 0 Luciferase-like monooxygenase Rootletin PF15035.1 AIO02610.1 - 0.033 14.1 6.9 0.041 13.8 4.8 1.1 1 0 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion Baculo_PEP_C PF04513.7 AIO02610.1 - 0.07 12.9 0.0 0.083 12.7 0.0 1.1 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Leu_zip PF15294.1 AIO02610.1 - 0.072 12.1 4.3 0.13 11.3 2.9 1.5 1 1 0 1 1 1 0 Leucine zipper IncA PF04156.9 AIO02610.1 - 0.08 12.5 4.7 0.12 11.9 3.3 1.3 1 0 0 1 1 1 0 IncA protein TMF_DNA_bd PF12329.3 AIO02610.1 - 0.11 12.3 7.7 0.79 9.5 0.8 2.4 2 1 0 2 2 2 0 TATA element modulatory factor 1 DNA binding FlaC_arch PF05377.6 AIO02610.1 - 0.12 12.2 1.6 6.8 6.6 0.0 2.8 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) HlyD PF00529.15 AIO02610.1 - 0.13 11.5 6.4 0.18 11.0 4.4 1.2 1 0 0 1 1 1 0 HlyD family secretion protein bZIP_1 PF00170.16 AIO02610.1 - 0.2 11.6 7.4 2.7 8.0 1.0 2.7 2 1 0 2 2 2 0 bZIP transcription factor Cortex-I_coil PF09304.5 AIO02610.1 - 0.23 11.5 11.0 0.11 12.5 2.2 2.1 1 1 1 2 2 2 0 Cortexillin I, coiled coil DUF972 PF06156.8 AIO02610.1 - 0.51 10.7 3.9 1.3 9.4 0.5 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF972) DUF2968 PF11180.3 AIO02610.1 - 0.6 9.4 11.0 7 5.9 7.6 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF2968) FUSC PF04632.7 AIO02610.1 - 0.62 8.4 2.7 0.63 8.4 1.9 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family bZIP_2 PF07716.10 AIO02610.1 - 0.68 9.8 9.7 1.8 8.4 0.6 2.7 2 1 0 2 2 2 0 Basic region leucine zipper APG6 PF04111.7 AIO02610.1 - 1.4 7.8 5.5 1.8 7.5 3.8 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 SSFA2_C PF14723.1 AIO02610.1 - 2.1 8.0 6.0 2.1 8.0 0.1 2.1 2 0 0 2 2 2 0 Sperm-specific antigen 2 C-terminus DUF4355 PF14265.1 AIO02610.1 - 2.4 8.1 9.2 0.25 11.2 1.4 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4355) Lge1 PF11488.3 AIO02610.1 - 2.7 8.2 5.5 2.6 8.2 0.4 2.1 1 1 1 2 2 2 0 Transcriptional regulatory protein LGE1 DUF4140 PF13600.1 AIO02610.1 - 2.8 8.4 10.7 16 6.0 1.7 2.2 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) Prefoldin_2 PF01920.15 AIO02610.1 - 3.1 7.5 7.8 3.3 7.5 0.4 2.4 2 1 0 2 2 2 0 Prefoldin subunit CCDC-167 PF15188.1 AIO02610.1 - 3.9 7.4 7.1 12 5.9 0.2 2.3 1 1 1 2 2 2 0 Coiled-coil domain-containing protein 167 DivIC PF04977.10 AIO02610.1 - 4.1 6.9 10.1 1.6 8.2 1.3 2.5 2 1 1 3 3 3 0 Septum formation initiator ADIP PF11559.3 AIO02610.1 - 8.8 6.2 11.2 5 7.0 1.3 2.1 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding Cyt-b5 PF00173.23 AIO02611.1 - 8.9e-15 54.2 0.0 1e-14 54.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain SopD PF11047.3 AIO02612.1 - 0.12 11.2 0.1 0.21 10.4 0.0 1.3 1 0 0 1 1 1 0 Salmonella outer protein D Abhydrolase_6 PF12697.2 AIO02613.1 - 3.3e-12 46.7 7.7 9.2e-08 32.2 3.4 3.3 2 1 0 2 2 2 2 Alpha/beta hydrolase family WD40 PF00400.27 AIO02614.1 - 3.2e-18 64.8 8.5 0.00034 20.3 0.1 6.0 6 0 0 6 6 6 5 WD domain, G-beta repeat Flavodoxin_1 PF00258.20 AIO02615.1 - 1.8e-42 144.7 0.0 2.7e-23 82.5 0.0 6.5 5 2 1 6 6 6 4 Flavodoxin FAD_binding_1 PF00667.15 AIO02615.1 - 2.8e-20 72.7 0.0 6e-20 71.6 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain NAD_binding_1 PF00175.16 AIO02615.1 - 3.1e-13 50.2 0.0 3.2e-12 46.9 0.0 2.6 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain DCD PF06559.6 AIO02615.1 - 0.13 10.6 0.0 0.2 9.9 0.0 1.2 1 0 0 1 1 1 0 2'-deoxycytidine 5'-triphosphate deaminase (DCD) RPA PF10134.4 AIO02615.1 - 0.13 11.4 0.0 0.24 10.6 0.0 1.4 1 0 0 1 1 1 0 Replication initiator protein A RabGAP-TBC PF00566.13 AIO02616.1 - 0.00036 20.0 0.1 0.001 18.5 0.0 1.8 1 1 0 1 1 1 1 Rab-GTPase-TBC domain CH PF00307.26 AIO02617.1 - 0.052 13.5 0.0 0.5 10.4 0.0 2.6 2 1 0 2 2 2 0 Calponin homology (CH) domain CAMSAP_CH PF11971.3 AIO02617.1 - 0.11 12.2 0.0 0.28 10.8 0.0 1.6 1 0 0 1 1 1 0 CAMSAP CH domain PIG-P PF08510.7 AIO02618.1 - 1.5e-32 111.8 0.7 1.5e-32 111.8 0.5 1.5 2 0 0 2 2 2 1 PIG-P DPM2 PF07297.7 AIO02618.1 - 1.2 9.4 11.3 0.18 12.0 3.9 2.2 2 0 0 2 2 2 0 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) LMBR1 PF04791.11 AIO02618.1 - 1.5 7.3 6.8 0.27 9.7 0.1 2.0 2 0 0 2 2 2 0 LMBR1-like membrane protein DUF1749 PF08538.5 AIO02621.1 - 5.7e-13 48.4 0.1 8.4e-13 47.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1749) Abhydrolase_6 PF12697.2 AIO02621.1 - 1.1e-06 28.7 1.0 1.6e-06 28.2 0.7 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family FRD2 PF03197.8 AIO02622.1 - 0.073 13.6 0.0 0.17 12.4 0.0 1.5 1 0 0 1 1 1 0 Bacteriophage FRD2 protein Spermine_synth PF01564.12 AIO02623.1 - 0.00011 21.2 0.0 0.00017 20.6 0.0 1.2 1 0 0 1 1 1 1 Spermine/spermidine synthase Methyltransf_26 PF13659.1 AIO02623.1 - 0.00011 22.1 0.2 0.00032 20.7 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_24 PF13578.1 AIO02623.1 - 0.01 16.6 0.0 0.034 14.9 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_23 PF13489.1 AIO02623.1 - 0.018 14.7 0.0 0.031 13.9 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_30 PF05430.6 AIO02623.1 - 0.032 13.9 0.0 0.067 12.8 0.0 1.5 1 0 0 1 1 1 0 S-adenosyl-L-methionine-dependent methyltransferase DUF3874 PF12990.2 AIO02623.1 - 0.092 12.8 0.0 0.27 11.3 0.0 1.8 1 0 0 1 1 1 0 Domain of unknonw function from B. Theta Gene description (DUF3874) PPR_2 PF13041.1 AIO02624.1 - 3.7e-40 135.6 9.1 1.7e-15 56.7 0.4 5.1 2 1 3 5 5 5 5 PPR repeat family PPR_3 PF13812.1 AIO02624.1 - 2.7e-36 120.7 5.2 1.3e-08 34.4 0.1 6.3 6 0 0 6 6 6 5 Pentatricopeptide repeat domain PPR PF01535.15 AIO02624.1 - 7.5e-33 110.2 1.1 2.6e-06 27.0 0.0 6.1 6 0 0 6 6 6 5 PPR repeat PPR_1 PF12854.2 AIO02624.1 - 5e-27 93.0 1.2 3e-09 36.1 0.1 6.1 6 0 0 6 6 6 5 PPR repeat TPR_7 PF13176.1 AIO02624.1 - 0.048 13.4 0.0 31 4.7 0.0 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_19 PF14559.1 AIO02624.1 - 0.069 13.5 0.0 18 5.7 0.0 3.5 3 1 0 3 3 3 0 Tetratricopeptide repeat BTAD PF03704.12 AIO02624.1 - 0.074 13.3 2.7 9.1 6.5 0.2 3.4 3 1 0 3 3 3 0 Bacterial transcriptional activator domain ECSIT PF06239.6 AIO02624.1 - 0.15 10.9 0.2 4.1 6.1 0.0 2.7 1 1 2 3 3 3 0 Evolutionarily conserved signalling intermediate in Toll pathway WD40 PF00400.27 AIO02625.1 - 1.9e-49 163.8 13.1 2.4e-09 36.7 0.1 7.6 7 0 0 7 7 7 7 WD domain, G-beta repeat AAA_16 PF13191.1 AIO02626.1 - 0.0062 16.5 0.1 0.013 15.4 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain Miro PF08477.8 AIO02626.1 - 0.055 13.9 0.0 0.96 9.9 0.0 2.3 2 0 0 2 2 2 0 Miro-like protein MttA_Hcf106 PF02416.11 AIO02626.1 - 0.12 11.4 0.6 4 6.6 0.0 2.4 2 0 0 2 2 2 0 mttA/Hcf106 family LRR_4 PF12799.2 AIO02627.1 - 1.5e-39 132.9 31.0 0.00032 20.2 0.6 14.3 9 2 2 13 13 13 9 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 AIO02627.1 - 2.5e-15 55.9 53.4 1.6e-05 24.5 1.3 10.3 8 3 3 11 11 11 8 Leucine rich repeat LRR_6 PF13516.1 AIO02627.1 - 1.1e-07 31.1 60.2 0.016 15.2 0.1 17.4 19 3 3 22 22 22 4 Leucine Rich repeat LRR_9 PF14580.1 AIO02627.1 - 0.22 11.0 8.2 0.2 11.1 0.7 3.7 2 2 1 3 3 3 0 Leucine-rich repeat LRR_1 PF00560.28 AIO02627.1 - 1 9.6 58.8 12 6.4 0.1 17.0 19 1 0 19 19 19 0 Leucine Rich Repeat FlaC_arch PF05377.6 AIO02628.1 - 0.023 14.5 1.4 4.4 7.2 0.1 2.6 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) CENP-Q PF13094.1 AIO02628.1 - 0.034 14.1 8.5 0.11 12.5 0.5 3.1 3 0 0 3 3 3 0 CENP-Q, a CENPA-CAD centromere complex subunit TBPIP PF07106.8 AIO02628.1 - 0.073 12.6 3.0 1.3 8.5 0.6 2.4 2 0 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) 2_5_RNA_ligase2 PF13563.1 AIO02629.1 - 0.0084 15.8 0.1 0.024 14.3 0.1 1.7 1 1 0 1 1 1 1 2'-5' RNA ligase superfamily DUF1045 PF06299.7 AIO02629.1 - 0.059 13.0 0.0 0.093 12.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1045) AFP PF02420.10 AIO02629.1 - 0.15 12.2 1.0 0.41 10.9 0.0 2.3 2 0 0 2 2 2 0 Insect antifreeze protein repeat MtN3_slv PF03083.11 AIO02630.1 - 4.9e-22 77.6 19.8 1e-14 54.1 0.5 2.6 3 0 0 3 3 3 2 Sugar efflux transporter for intercellular exchange DUF1011 PF06237.7 AIO02630.1 - 7.9 6.4 15.3 1.8 8.4 0.1 3.5 2 1 0 3 3 3 0 Protein of unknown function (DUF1011) LRR_4 PF12799.2 AIO02631.1 - 6.5e-18 63.9 3.4 7.7e-06 25.4 0.3 4.4 3 2 1 4 4 4 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 AIO02631.1 - 1.3e-14 53.7 9.6 6.5e-08 32.2 0.5 2.9 3 0 0 3 3 3 2 Leucine rich repeat LRR_9 PF14580.1 AIO02631.1 - 1.9e-09 37.3 0.2 2.9e-07 30.1 0.2 2.5 1 1 1 2 2 2 1 Leucine-rich repeat LRR_1 PF00560.28 AIO02631.1 - 2.6e-08 32.7 11.5 2 8.7 0.0 6.5 6 0 0 6 6 6 3 Leucine Rich Repeat LRR_6 PF13516.1 AIO02631.1 - 0.001 18.8 16.5 0.13 12.4 0.2 6.3 4 2 2 6 6 6 1 Leucine Rich repeat LRR_7 PF13504.1 AIO02631.1 - 0.0043 17.0 24.1 1.9 9.0 0.0 7.1 8 0 0 8 8 8 3 Leucine rich repeat RNase_PH PF01138.16 AIO02632.1 - 2.4e-15 57.0 0.3 4.1e-15 56.2 0.2 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 Phage_gp49_66 PF13876.1 AIO02632.1 - 0.12 12.4 0.1 0.22 11.5 0.0 1.4 1 0 0 1 1 1 0 Phage protein (N4 Gp49/phage Sf6 gene 66) family SDH_beta PF03315.10 AIO02632.1 - 0.15 12.0 0.1 6.6 6.7 0.1 2.2 2 0 0 2 2 2 0 Serine dehydratase beta chain Clathrin PF00637.15 AIO02633.1 - 3.6e-08 33.1 0.2 3.6e-08 33.1 0.1 2.1 3 0 0 3 3 3 1 Region in Clathrin and VPS Vps8 PF12816.2 AIO02633.1 - 7.6e-05 22.0 0.1 0.76 8.9 0.0 3.7 4 0 0 4 4 4 3 Golgi CORVET complex core vacuolar protein 8 zf-rbx1 PF12678.2 AIO02633.1 - 0.0033 17.4 1.8 0.0079 16.2 1.2 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_2 PF13639.1 AIO02633.1 - 0.015 15.0 1.4 0.048 13.4 1.0 1.9 1 0 0 1 1 1 0 Ring finger domain CH PF00307.26 AIO02635.1 - 2.5e-06 27.4 0.0 5.1e-06 26.4 0.0 1.6 1 0 0 1 1 1 1 Calponin homology (CH) domain IF-2B PF01008.12 AIO02636.1 - 2.5e-71 239.9 0.1 2.9e-71 239.7 0.0 1.0 1 0 0 1 1 1 1 Initiation factor 2 subunit family UPF0029 PF01205.14 AIO02637.1 - 9.3e-26 89.6 0.0 1.5e-25 89.0 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized protein family UPF0029 RWD PF05773.17 AIO02637.1 - 0.0025 17.7 0.3 0.0056 16.5 0.2 1.7 1 1 0 1 1 1 1 RWD domain 2OG-FeII_Oxy_2 PF13532.1 AIO02638.1 - 9.4e-09 35.3 0.0 4.3e-08 33.2 0.0 2.1 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 AIO02638.1 - 2.9e-06 27.5 0.0 6.3e-06 26.4 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_3 PF13640.1 AIO02638.1 - 0.083 13.4 0.1 0.19 12.2 0.0 1.6 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily DUF1228 PF06779.9 AIO02639.1 - 0.036 14.0 0.0 0.083 12.9 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1228) DnaJ PF00226.26 AIO02640.1 - 8.2e-08 31.8 0.0 2e-07 30.6 0.0 1.7 1 0 0 1 1 1 1 DnaJ domain HTH_38 PF13936.1 AIO02640.1 - 0.011 15.3 0.0 0.028 13.9 0.0 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain KorB PF08535.5 AIO02640.1 - 0.044 13.9 0.0 0.19 11.8 0.0 2.1 2 0 0 2 2 2 0 KorB domain Rz1 PF06085.6 AIO02640.1 - 0.2 11.1 0.6 0.42 10.0 0.4 1.5 1 0 0 1 1 1 0 Lipoprotein Rz1 precursor PSP1 PF04468.7 AIO02641.1 - 0.012 15.5 0.0 0.022 14.7 0.0 1.4 1 0 0 1 1 1 0 PSP1 C-terminal conserved region Tubulin PF00091.20 AIO02642.1 - 0.00012 21.9 0.0 0.00019 21.3 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Ribosomal_S2 PF00318.15 AIO02644.1 - 3.7e-44 150.4 0.2 4.2e-24 84.9 0.1 2.1 1 1 1 2 2 2 2 Ribosomal protein S2 Sulfotransfer_1 PF00685.22 AIO02644.1 - 0.014 14.6 0.0 0.019 14.2 0.0 1.2 1 0 0 1 1 1 0 Sulfotransferase domain Cep57_CLD_2 PF14197.1 AIO02645.1 - 0.0022 17.8 10.9 0.0022 17.8 7.5 10.2 7 4 3 10 10 10 2 Centrosome localisation domain of PPC89 Reo_sigmaC PF04582.7 AIO02645.1 - 1.7 7.7 28.0 0.15 11.1 3.4 5.3 5 1 1 6 6 6 0 Reovirus sigma C capsid protein DUF2451 PF10474.4 AIO02646.1 - 0.023 14.4 2.6 0.049 13.3 1.8 1.6 1 1 0 1 1 1 0 Protein of unknown function C-terminus (DUF2451) YojJ PF10372.4 AIO02646.1 - 0.038 13.8 0.2 0.19 11.6 0.1 2.3 1 0 0 1 1 1 0 Bacterial membrane-spanning protein N-terminus DUF16 PF01519.11 AIO02646.1 - 0.076 13.2 19.7 16 5.7 0.0 3.4 2 1 0 2 2 2 0 Protein of unknown function DUF16 Baculo_PEP_C PF04513.7 AIO02646.1 - 0.13 12.0 9.0 3.9 7.2 2.4 3.7 2 1 2 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus Tweety PF04906.8 AIO02646.1 - 0.14 10.5 10.9 2.1 6.6 3.2 3.3 3 1 0 3 3 3 0 Tweety DUF948 PF06103.6 AIO02646.1 - 0.27 11.1 12.5 0.082 12.7 1.2 4.1 3 1 0 4 4 4 0 Bacterial protein of unknown function (DUF948) Glyco_tran_WbsX PF14307.1 AIO02646.1 - 1.1 8.3 4.2 0.21 10.7 0.4 1.6 2 0 0 2 2 2 0 Glycosyltransferase WbsX FliD_C PF07195.7 AIO02646.1 - 1.6 7.9 11.5 1.3 8.3 2.0 2.8 3 0 0 3 3 3 0 Flagellar hook-associated protein 2 C-terminus DUF1664 PF07889.7 AIO02646.1 - 1.9 8.2 16.7 0.087 12.6 3.4 3.5 3 1 0 4 4 4 0 Protein of unknown function (DUF1664) DUF1640 PF07798.6 AIO02646.1 - 2.6 8.0 19.6 0.49 10.4 8.5 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF1640) Hexapep PF00132.19 AIO02647.1 - 1e-08 34.2 12.5 0.0034 16.8 0.1 4.8 3 1 0 4 4 4 4 Bacterial transferase hexapeptide (six repeats) NOB1_Zn_bind PF08772.6 AIO02649.1 - 7.6e-29 99.3 0.1 1.5e-28 98.3 0.1 1.6 1 0 0 1 1 1 1 Nin one binding (NOB1) Zn-ribbon like DZR PF12773.2 AIO02649.1 - 0.014 15.2 0.4 0.027 14.2 0.3 1.4 1 0 0 1 1 1 0 Double zinc ribbon zf-ribbon_3 PF13248.1 AIO02649.1 - 0.061 12.5 0.8 0.11 11.7 0.5 1.4 1 0 0 1 1 1 0 zinc-ribbon domain DUF35_N PF12172.3 AIO02649.1 - 0.12 12.2 1.8 0.31 11.0 1.2 1.7 1 1 0 1 1 1 0 Rubredoxin-like zinc ribbon domain (DUF35_N) AF1Q PF15017.1 AIO02649.1 - 4.3 7.3 9.1 26 4.7 6.3 2.2 1 1 0 1 1 1 0 Drug resistance and apoptosis regulator zf-NADH-PPase PF09297.6 AIO02649.1 - 9.2 5.8 6.5 19 4.8 0.9 2.6 2 0 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain DUF3123 PF11321.3 AIO02650.1 - 0.015 15.5 0.2 0.062 13.5 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3123) CK_II_beta PF01214.13 AIO02652.1 - 6.4e-76 253.9 0.0 7.9e-76 253.6 0.0 1.1 1 0 0 1 1 1 1 Casein kinase II regulatory subunit DUF4496 PF14908.1 AIO02654.1 - 3.4e-32 111.2 0.1 4.7e-32 110.7 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4496) Ribosomal_S2 PF00318.15 AIO02655.1 - 3.7e-44 150.4 0.2 4.2e-24 84.9 0.1 2.1 1 1 1 2 2 2 2 Ribosomal protein S2 Sulfotransfer_1 PF00685.22 AIO02655.1 - 0.014 14.6 0.0 0.019 14.2 0.0 1.2 1 0 0 1 1 1 0 Sulfotransferase domain Porin_3 PF01459.17 AIO02656.1 - 0.00011 21.6 0.0 0.002 17.4 0.0 2.6 1 1 0 1 1 1 1 Eukaryotic porin VHS PF00790.14 AIO02657.1 - 9.3e-09 35.0 0.0 2.1e-08 33.9 0.0 1.5 1 0 0 1 1 1 1 VHS domain Kinesin PF00225.18 AIO02658.1 - 6.8e-25 87.4 11.1 1.5e-18 66.6 0.0 3.4 3 1 1 4 4 4 2 Kinesin motor domain CemA PF03040.9 AIO02658.1 - 7.2 6.1 6.3 19 4.7 4.4 1.7 1 0 0 1 1 1 0 CemA family MIF4G PF02854.14 AIO02659.1 - 9.9e-12 44.7 0.3 9.9e-12 44.7 0.2 2.1 2 0 0 2 2 2 1 MIF4G domain MA3 PF02847.12 AIO02659.1 - 1.5e-11 43.9 1.9 2.6e-11 43.2 0.2 2.1 2 0 0 2 2 2 1 MA3 domain VPS28 PF03997.7 AIO02660.1 - 1.3e-41 142.3 0.2 1.5e-41 142.1 0.1 1.0 1 0 0 1 1 1 1 VPS28 protein Phage_Mu_Gam PF07352.7 AIO02660.1 - 0.0074 15.8 0.0 0.012 15.1 0.0 1.3 1 0 0 1 1 1 1 Bacteriophage Mu Gam like protein Aldedh PF00171.17 AIO02661.1 - 2.3e-127 425.1 1.1 2.7e-127 424.9 0.7 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family SNF2_N PF00176.18 AIO02662.1 - 1.1e-70 237.8 0.0 1.7e-70 237.2 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 AIO02662.1 - 8.8e-14 51.1 0.0 2.7e-13 49.5 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 AIO02662.1 - 8.8e-07 28.9 0.0 2.8e-06 27.2 0.0 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.24 AIO02662.1 - 3e-05 23.5 0.0 7.2e-05 22.3 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 AIO02662.1 - 0.048 13.8 0.0 0.18 11.9 0.0 2.0 1 0 0 1 1 1 0 AAA domain HDA2-3 PF11496.3 AIO02662.1 - 0.097 11.4 0.0 0.33 9.7 0.0 1.7 1 1 0 1 1 1 0 Class II histone deacetylase complex subunits 2 and 3 WD40 PF00400.27 AIO02663.1 - 0.51 10.3 18.3 2.7 8.0 0.1 7.1 8 0 0 8 8 8 0 WD domain, G-beta repeat Phosphonate-bd PF12974.2 AIO02665.1 - 0.056 12.8 0.0 0.13 11.6 0.0 1.5 1 0 0 1 1 1 0 ABC transporter, phosphonate, periplasmic substrate-binding protein Glyco_hydro_65m PF03632.10 AIO02666.1 - 1.1e-65 221.7 0.0 2.3e-65 220.7 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 65 central catalytic domain Glyco_hydro_65N PF03636.10 AIO02666.1 - 1e-16 61.0 0.1 2e-16 60.1 0.1 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 65, N-terminal domain HAD_2 PF13419.1 AIO02666.1 - 3.3e-08 33.9 0.1 1e-07 32.3 0.0 1.8 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Glyco_hydro_65C PF03633.10 AIO02666.1 - 0.004 17.1 0.0 0.011 15.8 0.0 1.7 1 0 0 1 1 1 1 Glycosyl hydrolase family 65, C-terminal domain Mod_r PF07200.8 AIO02667.1 - 0.012 15.5 7.3 0.21 11.5 3.8 2.9 2 0 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein Myosin_tail_1 PF01576.14 AIO02667.1 - 0.071 10.8 12.7 0.21 9.2 0.1 2.5 2 0 0 2 2 2 0 Myosin tail DUF972 PF06156.8 AIO02667.1 - 0.072 13.4 3.2 8.8 6.7 0.7 3.4 2 0 0 2 2 2 0 Protein of unknown function (DUF972) IncA PF04156.9 AIO02667.1 - 0.21 11.1 20.2 2.7 7.5 2.1 3.5 2 1 0 2 2 2 0 IncA protein ADIP PF11559.3 AIO02667.1 - 0.22 11.4 12.6 4 7.3 0.1 2.8 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding WXG100 PF06013.7 AIO02667.1 - 0.24 11.4 6.1 0.4 10.7 0.0 3.6 3 0 0 3 3 3 0 Proteins of 100 residues with WXG ERM PF00769.14 AIO02667.1 - 0.25 10.8 15.4 0.0089 15.5 5.1 2.6 3 0 0 3 3 3 0 Ezrin/radixin/moesin family Tropomyosin_1 PF12718.2 AIO02667.1 - 5.9 6.7 15.2 1.8 8.4 0.2 3.0 3 0 0 3 3 3 0 Tropomyosin like APG6 PF04111.7 AIO02667.1 - 8.5 5.3 10.2 14 4.5 3.8 2.6 2 0 0 2 2 2 0 Autophagy protein Apg6 Fe_hyd_lg_C PF02906.9 AIO02668.1 - 0.024 13.9 1.0 0.48 9.6 0.3 2.3 1 1 0 2 2 2 0 Iron only hydrogenase large subunit, C-terminal domain Adaptin_N PF01602.15 AIO02669.1 - 1.4e-79 267.7 0.0 1.8e-79 267.4 0.0 1.0 1 0 0 1 1 1 1 Adaptin N terminal region HEAT_2 PF13646.1 AIO02669.1 - 3.3e-08 33.6 7.3 3e-05 24.2 1.6 4.0 2 2 2 4 4 4 2 HEAT repeats HEAT PF02985.17 AIO02669.1 - 3.4e-06 26.6 2.5 0.44 10.7 0.1 4.2 3 0 0 3 3 3 3 HEAT repeat Exo_endo_phos PF03372.18 AIO02670.1 - 9.1e-18 65.0 0.0 8.2e-15 55.4 0.0 2.3 2 0 0 2 2 2 2 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.1 AIO02670.1 - 5.9e-07 29.1 0.0 0.0068 16.0 0.0 2.5 2 0 0 2 2 2 2 Endonuclease-reverse transcriptase Ax_dynein_light PF10211.4 AIO02671.1 - 0.059 13.2 0.1 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 Axonemal dynein light chain RasGEF_N_2 PF14663.1 AIO02671.1 - 0.092 12.6 1.0 23 4.9 0.0 3.7 5 0 0 5 5 5 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain HEAT PF02985.17 AIO02671.1 - 0.27 11.4 9.7 8.8 6.7 0.0 6.0 5 1 1 6 6 6 0 HEAT repeat Cnl2_NKP2 PF09447.5 AIO02672.1 - 0.069 12.8 1.6 0.36 10.5 0.4 2.4 2 0 0 2 2 2 0 Cnl2/NKP2 family protein RdRP_4 PF02123.11 AIO02672.1 - 0.36 9.4 3.4 0.61 8.7 2.4 1.3 1 1 0 1 1 1 0 Viral RNA-directed RNA-polymerase GST_C_2 PF13410.1 AIO02675.1 - 1.9e-09 37.2 0.4 6.6e-09 35.5 0.1 2.1 1 1 1 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 AIO02675.1 - 4.7e-05 23.7 0.0 0.00013 22.4 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain DUF4363 PF14276.1 AIO02677.1 - 5.7 6.6 9.4 0.25 11.0 0.5 3.3 3 1 0 3 3 3 0 Domain of unknown function (DUF4363) Pkinase PF00069.20 AIO02678.1 - 3.6e-56 190.1 0.0 5.4e-56 189.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AIO02678.1 - 2.1e-36 125.3 0.2 4.3e-36 124.3 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 AIO02678.1 - 1.2e-09 37.6 0.1 1.6e-07 30.6 0.0 2.6 3 0 0 3 3 3 1 Kinase-like APH PF01636.18 AIO02678.1 - 3.6e-05 23.6 0.0 0.11 12.1 0.0 3.4 2 1 1 3 3 3 2 Phosphotransferase enzyme family zf-C2H2_jaz PF12171.3 AIO02678.1 - 0.0038 17.3 0.9 0.029 14.5 0.1 2.6 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding Kdo PF06293.9 AIO02678.1 - 0.013 14.5 0.0 0.026 13.5 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.6 AIO02678.1 - 0.017 13.9 0.0 0.031 13.1 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 FYVE_2 PF02318.11 AIO02678.1 - 0.072 12.9 4.5 0.2 11.5 3.1 1.7 1 0 0 1 1 1 0 FYVE-type zinc finger IBR PF01485.16 AIO02678.1 - 0.37 10.6 6.0 0.88 9.4 4.0 1.6 1 1 0 1 1 1 0 IBR domain ZZ PF00569.12 AIO02678.1 - 0.58 9.7 8.9 2.4 7.7 6.2 2.1 1 1 0 1 1 1 0 Zinc finger, ZZ type C1_3 PF07649.7 AIO02678.1 - 0.67 10.0 10.9 0.35 10.9 5.3 2.1 2 0 0 2 2 2 0 C1-like domain Ubie_methyltran PF01209.13 AIO02679.1 - 2.2e-107 357.5 0.0 2.5e-107 357.3 0.0 1.0 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_11 PF08241.7 AIO02679.1 - 1.2e-16 60.9 0.0 2.2e-16 60.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 AIO02679.1 - 8.5e-12 44.9 0.0 1.3e-11 44.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 AIO02679.1 - 1.3e-10 41.5 0.0 2.3e-10 40.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 AIO02679.1 - 1.2e-07 32.1 0.0 1.9e-07 31.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 AIO02679.1 - 5.8e-07 29.3 0.0 8.1e-07 28.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 AIO02679.1 - 0.00021 21.8 0.1 0.00043 20.8 0.1 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.10 AIO02679.1 - 0.00024 20.8 0.0 0.019 14.6 0.0 2.6 2 1 1 3 3 3 1 Hypothetical methyltransferase Y_phosphatase PF00102.22 AIO02681.1 - 2.6e-63 213.5 0.0 3.6e-63 213.0 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.15 AIO02681.1 - 0.00095 18.7 2.0 0.0014 18.1 0.0 2.3 3 0 0 3 3 3 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.1 AIO02681.1 - 0.0014 18.9 0.0 0.0038 17.4 0.0 1.8 1 0 0 1 1 1 1 Tyrosine phosphatase family PTPlike_phytase PF14566.1 AIO02681.1 - 0.02 14.9 0.0 0.052 13.5 0.0 1.7 1 0 0 1 1 1 0 Inositol hexakisphosphate Pyr_redox_2 PF07992.9 AIO02682.1 - 1.7e-30 106.4 0.0 5.2e-30 104.8 0.0 2.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 AIO02682.1 - 1.6e-12 47.6 0.1 2e-08 34.5 0.1 2.8 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 AIO02682.1 - 9.8e-07 29.0 0.0 2.2e-05 24.5 0.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 AIO02682.1 - 5.3e-06 25.5 0.0 0.0036 16.2 0.0 2.7 3 0 0 3 3 3 2 FAD binding domain NAD_binding_8 PF13450.1 AIO02682.1 - 8.3e-06 25.7 0.0 0.14 12.1 0.0 2.5 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain DAO PF01266.19 AIO02682.1 - 0.00059 18.8 0.2 1.5 7.6 0.0 3.2 2 1 1 3 3 3 2 FAD dependent oxidoreductase GIDA PF01134.17 AIO02682.1 - 0.0021 16.9 0.0 0.87 8.3 0.0 3.1 3 0 0 3 3 3 1 Glucose inhibited division protein A NAD_binding_7 PF13241.1 AIO02682.1 - 0.02 15.1 0.4 1 9.6 0.0 3.2 3 1 0 3 3 3 0 Putative NAD(P)-binding Trp_halogenase PF04820.9 AIO02682.1 - 0.036 12.7 0.0 9.9 4.6 0.0 2.8 2 1 1 3 3 3 0 Tryptophan halogenase Lycopene_cycl PF05834.7 AIO02682.1 - 0.066 12.1 0.1 8.8 5.1 0.0 2.9 3 0 0 3 3 3 0 Lycopene cyclase protein Pribosyltran_N PF13793.1 AIO02683.1 - 8.1e-39 131.9 0.2 4.2e-38 129.6 0.0 2.1 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.1 AIO02683.1 - 2.6e-30 105.5 1.9 5e-30 104.6 0.7 1.8 1 1 1 2 2 2 1 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.22 AIO02683.1 - 1.5e-12 47.3 0.2 4.3e-12 45.8 0.2 1.8 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.1 AIO02683.1 - 0.00028 20.1 0.1 0.00063 19.0 0.1 1.6 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase BCS1_N PF08740.6 AIO02684.1 - 4.9e-38 130.6 0.5 7.4e-38 130.0 0.3 1.3 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.24 AIO02684.1 - 1.7e-11 44.4 0.0 1.1e-05 25.7 0.0 2.9 2 1 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 AIO02684.1 - 3.9e-05 24.4 0.0 0.00012 22.8 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 AIO02684.1 - 0.00058 19.5 0.3 0.0037 16.9 0.0 2.5 3 0 0 3 3 3 1 Part of AAA domain AAA_5 PF07728.9 AIO02684.1 - 0.0019 17.9 0.0 0.0041 16.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.7 AIO02684.1 - 0.002 17.2 0.0 0.0034 16.4 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 AIO02684.1 - 0.006 16.5 0.3 0.089 12.7 0.0 2.6 2 0 0 2 2 2 1 AAA ATPase domain AAA_11 PF13086.1 AIO02684.1 - 0.0083 15.7 0.0 0.016 14.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 AIO02684.1 - 0.013 15.3 0.0 0.013 15.3 0.0 2.2 3 0 0 3 3 2 0 AAA domain TIP49 PF06068.8 AIO02684.1 - 0.019 13.6 0.0 0.032 12.9 0.0 1.2 1 0 0 1 1 1 0 TIP49 C-terminus AAA_3 PF07726.6 AIO02684.1 - 0.061 12.9 0.0 0.17 11.5 0.0 1.7 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.1 AIO02684.1 - 0.089 12.1 0.0 0.26 10.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain KaiC PF06745.8 AIO02684.1 - 0.093 11.8 0.0 0.21 10.6 0.0 1.5 1 0 0 1 1 1 0 KaiC AAA_24 PF13479.1 AIO02684.1 - 0.22 11.0 0.9 3.7 7.0 0.1 2.3 2 0 0 2 2 2 0 AAA domain AIRS_C PF02769.17 AIO02685.1 - 1.6e-16 60.6 0.0 3.6e-16 59.5 0.0 1.6 1 1 0 1 1 1 1 AIR synthase related protein, C-terminal domain AIRS PF00586.19 AIO02685.1 - 8.2e-08 32.3 0.1 1.7e-07 31.4 0.0 1.5 1 0 0 1 1 1 1 AIR synthase related protein, N-terminal domain Extensin-like_C PF06904.7 AIO02685.1 - 0.024 14.4 0.0 0.042 13.6 0.0 1.3 1 0 0 1 1 1 0 Extensin-like protein C-terminus KH_1 PF00013.24 AIO02686.1 - 2.1e-05 24.0 0.0 3.8e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 KH domain KH_3 PF13014.1 AIO02686.1 - 0.0034 16.9 0.0 0.0078 15.8 0.0 1.5 1 0 0 1 1 1 1 KH domain L27_1 PF09058.5 AIO02686.1 - 0.11 12.4 0.0 0.28 11.0 0.0 1.7 1 0 0 1 1 1 0 L27_1 Ribosomal_60s PF00428.14 AIO02686.1 - 0.59 10.5 8.2 1.4 9.3 5.7 1.6 1 0 0 1 1 1 0 60s Acidic ribosomal protein TylF PF05711.6 AIO02687.1 - 6.1e-15 54.9 0.1 1.4e-06 27.6 0.2 2.5 2 1 0 2 2 2 2 Macrocin-O-methyltransferase (TylF) Methyltransf_24 PF13578.1 AIO02687.1 - 1.1e-06 29.3 0.1 5.9e-06 27.0 0.0 2.2 2 1 0 2 2 2 1 Methyltransferase domain CmcI PF04989.7 AIO02687.1 - 0.01 15.1 0.0 0.018 14.3 0.0 1.4 1 0 0 1 1 1 0 Cephalosporin hydroxylase SEP PF08059.8 AIO02688.1 - 1.2e-07 31.9 0.0 2.9e-07 30.6 0.0 1.7 1 0 0 1 1 1 1 SEP domain UBX PF00789.15 AIO02688.1 - 4.4e-05 23.4 0.0 9.7e-05 22.3 0.0 1.6 1 0 0 1 1 1 1 UBX domain IncA PF04156.9 AIO02688.1 - 0.057 13.0 5.2 0.12 11.9 3.6 1.4 1 0 0 1 1 1 0 IncA protein HMG_box PF00505.14 AIO02688.1 - 0.093 13.0 0.3 0.19 12.0 0.2 1.5 1 0 0 1 1 1 0 HMG (high mobility group) box Spc24 PF08286.6 AIO02688.1 - 0.1 12.3 4.6 0.2 11.3 3.2 1.6 1 0 0 1 1 1 0 Spc24 subunit of Ndc80 OmpH PF03938.9 AIO02688.1 - 0.11 12.3 4.1 0.26 11.2 2.4 1.8 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) TPR_MLP1_2 PF07926.7 AIO02688.1 - 0.22 11.2 9.8 0.075 12.7 4.5 1.8 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein APG6 PF04111.7 AIO02688.1 - 1.1 8.2 8.1 1.8 7.5 5.6 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 UPF0081 PF03652.10 AIO02689.1 - 0.021 14.9 0.0 0.038 14.1 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0081) DAO PF01266.19 AIO02690.1 - 1.9e-40 138.9 0.0 2.3e-40 138.6 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 AIO02690.1 - 0.00016 21.5 0.1 0.00041 20.3 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 AIO02690.1 - 0.00086 19.2 1.4 0.0028 17.5 0.1 2.3 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 AIO02690.1 - 0.002 17.1 0.1 0.0034 16.3 0.0 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein Mqo PF06039.10 AIO02690.1 - 0.0026 16.0 0.0 0.026 12.7 0.0 2.0 2 0 0 2 2 2 1 Malate:quinone oxidoreductase (Mqo) Thi4 PF01946.12 AIO02690.1 - 0.0039 16.3 0.2 0.038 13.0 0.0 2.4 3 0 0 3 3 3 1 Thi4 family FAD_binding_3 PF01494.14 AIO02690.1 - 0.0046 16.0 0.4 0.043 12.8 0.1 2.0 2 0 0 2 2 2 1 FAD binding domain TrkA_N PF02254.13 AIO02690.1 - 0.01 15.8 0.2 0.022 14.7 0.1 1.5 1 0 0 1 1 1 0 TrkA-N domain Pyr_redox PF00070.22 AIO02690.1 - 0.021 15.2 0.1 0.052 13.9 0.1 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 AIO02690.1 - 0.07 13.1 0.1 0.15 12.1 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase HlyIII PF03006.15 AIO02694.1 - 3.8e-52 176.9 27.1 4.6e-52 176.6 18.8 1.1 1 0 0 1 1 1 1 Haemolysin-III related DUF962 PF06127.6 AIO02694.1 - 0.026 14.3 1.1 0.17 11.8 0.7 2.6 1 1 0 1 1 1 0 Protein of unknown function (DUF962) HlyIII PF03006.15 AIO02695.1 - 7.7e-53 179.1 27.0 9.5e-53 178.8 18.7 1.1 1 0 0 1 1 1 1 Haemolysin-III related HlyIII PF03006.15 AIO02696.1 - 2.1e-53 181.0 28.5 2.5e-53 180.7 19.8 1.1 1 0 0 1 1 1 1 Haemolysin-III related PCIF1_WW PF12237.3 AIO02697.1 - 1.6e-34 118.6 0.2 1.4e-21 76.6 0.0 2.4 2 0 0 2 2 2 2 Phosphorylated CTD interacting factor 1 WW domain AAA_33 PF13671.1 AIO02698.1 - 0.0017 18.2 4.4 0.022 14.6 0.6 3.6 1 1 1 2 2 2 1 AAA domain KTI12 PF08433.5 AIO02698.1 - 0.017 14.3 0.8 1 8.4 0.0 2.5 2 1 0 2 2 2 0 Chromatin associated protein KTI12 AAA_25 PF13481.1 AIO02698.1 - 0.028 13.8 0.4 0.16 11.3 0.0 2.3 3 0 0 3 3 3 0 AAA domain AAA_29 PF13555.1 AIO02698.1 - 0.03 13.8 0.0 0.075 12.5 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_19 PF13245.1 AIO02698.1 - 0.048 13.4 0.9 0.59 9.9 0.0 2.8 2 1 0 2 2 2 0 Part of AAA domain AAA_17 PF13207.1 AIO02698.1 - 0.094 13.5 0.0 0.28 12.0 0.0 1.9 1 1 0 1 1 1 0 AAA domain Peptidase_M24 PF00557.19 AIO02700.1 - 1.6e-34 119.3 0.0 2.6e-34 118.6 0.0 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.11 AIO02700.1 - 4.7e-10 38.9 0.0 1.1e-09 37.7 0.0 1.7 1 1 0 1 1 1 1 Aminopeptidase P, N-terminal domain Clathrin_bdg PF15045.1 AIO02700.1 - 0.16 11.5 0.0 0.34 10.4 0.0 1.5 1 0 0 1 1 1 0 Clathrin-binding box of Aftiphilin, vesicle trafficking EMP24_GP25L PF01105.19 AIO02701.1 - 1.4e-12 47.7 0.0 1.8e-12 47.3 0.0 1.3 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Transcript_VP30 PF11507.3 AIO02702.1 - 0.06 13.1 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 Ebola virus-specific transcription factor VP30 HrpB2 PF09487.5 AIO02702.1 - 0.097 12.8 0.0 0.24 11.6 0.0 1.6 1 0 0 1 1 1 0 Bacterial type III secretion protein (HrpB2) CAP_C PF08603.6 AIO02703.1 - 6.7e-50 168.5 2.4 8.8e-50 168.1 1.6 1.1 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) C terminal CAP_N PF01213.14 AIO02703.1 - 1.2e-12 47.7 1.1 2.1e-12 46.9 0.7 1.4 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) N terminal TBCC PF07986.7 AIO02703.1 - 4.2e-05 22.9 6.8 6.9e-05 22.2 4.7 1.3 1 0 0 1 1 1 1 Tubulin binding cofactor C NERD PF08378.6 AIO02705.1 - 1.8e-27 95.9 0.4 4.3e-27 94.6 0.3 1.7 1 1 0 1 1 1 1 Nuclease-related domain DUF3025 PF11227.3 AIO02705.1 - 0.36 10.2 2.9 0.41 10.1 0.5 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3025) tRNA-synt_1 PF00133.17 AIO02706.1 - 8.5e-215 714.2 0.1 8.5e-215 714.2 0.1 1.8 2 0 0 2 2 2 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 AIO02706.1 - 3.7e-21 75.4 0.0 1.2e-20 73.8 0.0 1.9 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.6 AIO02706.1 - 1.1e-16 60.4 3.2 2e-06 26.7 0.6 4.0 3 1 0 3 3 3 3 tRNA synthetases class I (M) tRNA-synt_1e PF01406.14 AIO02706.1 - 0.002 17.3 0.6 0.086 11.9 0.0 3.0 2 1 1 3 3 3 1 tRNA synthetases class I (C) catalytic domain SWIM PF04434.12 AIO02707.1 - 0.15 11.5 1.4 0.3 10.5 1.0 1.4 1 0 0 1 1 1 0 SWIM zinc finger Cyclin_N PF00134.18 AIO02708.1 - 5.1e-05 22.8 0.1 0.00072 19.1 0.0 2.5 2 0 0 2 2 2 1 Cyclin, N-terminal domain DAO PF01266.19 AIO02710.1 - 2.6e-19 69.3 5.9 1.6e-09 37.1 0.3 2.7 2 1 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 AIO02710.1 - 1.3e-07 31.5 0.6 5e-07 29.6 0.5 1.9 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 AIO02710.1 - 1.1e-05 25.7 0.6 3.2e-05 24.2 0.4 1.8 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 AIO02710.1 - 1.2e-05 25.2 0.0 0.00021 21.2 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 AIO02710.1 - 0.00021 20.4 0.1 0.00041 19.5 0.0 1.4 1 0 0 1 1 1 1 Thi4 family GIDA PF01134.17 AIO02710.1 - 0.00035 19.5 0.2 0.00085 18.2 0.2 1.6 2 0 0 2 2 2 1 Glucose inhibited division protein A Pyr_redox_3 PF13738.1 AIO02710.1 - 0.00085 19.4 0.1 0.0027 17.7 0.1 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 AIO02710.1 - 0.0051 15.7 1.4 0.0082 15.0 1.0 1.3 1 0 0 1 1 1 1 FAD binding domain 3HCDH_N PF02737.13 AIO02710.1 - 0.0068 16.0 0.4 0.014 15.0 0.3 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_10 PF13460.1 AIO02710.1 - 0.018 15.0 0.3 0.34 10.8 0.2 2.4 2 0 0 2 2 2 0 NADH(P)-binding HI0933_like PF03486.9 AIO02710.1 - 0.022 13.2 0.4 0.033 12.6 0.3 1.2 1 0 0 1 1 1 0 HI0933-like protein FAD_binding_3 PF01494.14 AIO02710.1 - 0.031 13.3 0.5 0.06 12.3 0.3 1.4 1 0 0 1 1 1 0 FAD binding domain NAD_binding_9 PF13454.1 AIO02710.1 - 0.061 13.0 0.2 0.14 11.8 0.1 1.6 1 0 0 1 1 1 0 FAD-NAD(P)-binding Lycopene_cycl PF05834.7 AIO02710.1 - 0.07 12.0 0.1 0.12 11.2 0.1 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein NAD_binding_2 PF03446.10 AIO02710.1 - 0.12 12.1 0.0 0.25 11.1 0.0 1.4 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Shikimate_DH PF01488.15 AIO02710.1 - 0.14 12.2 0.1 0.29 11.2 0.1 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase FAD_oxidored PF12831.2 AIO02710.1 - 0.56 9.2 4.1 0.2 10.6 0.6 2.0 2 1 0 2 2 2 0 FAD dependent oxidoreductase OB_NTP_bind PF07717.11 AIO02711.1 - 1.2e-24 86.3 0.0 2.2e-24 85.4 0.0 1.5 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.18 AIO02711.1 - 2.2e-13 50.0 0.3 5.4e-13 48.8 0.2 1.7 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.26 AIO02711.1 - 2.4e-11 43.3 0.0 6.8e-11 41.8 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 AIO02711.1 - 2.6e-10 40.0 0.0 4.8e-10 39.1 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 AIO02711.1 - 2e-05 24.7 0.0 7e-05 22.9 0.0 1.9 1 0 0 1 1 1 1 AAA domain T2SE PF00437.15 AIO02711.1 - 0.0071 15.2 0.2 0.029 13.2 0.0 2.0 2 0 0 2 2 2 1 Type II/IV secretion system protein PhoH PF02562.11 AIO02711.1 - 0.0081 15.4 0.0 0.06 12.5 0.0 2.4 3 0 0 3 3 3 1 PhoH-like protein AAA_16 PF13191.1 AIO02711.1 - 0.0094 15.9 0.6 0.075 13.0 0.0 2.6 3 1 0 3 3 3 1 AAA ATPase domain FtsK_SpoIIIE PF01580.13 AIO02711.1 - 0.012 15.0 0.0 0.022 14.2 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family ResIII PF04851.10 AIO02711.1 - 0.02 14.6 0.1 2.3 7.9 0.0 2.3 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit KaiC PF06745.8 AIO02711.1 - 0.028 13.5 0.0 0.06 12.4 0.0 1.4 1 0 0 1 1 1 0 KaiC Kringle PF00051.13 AIO02711.1 - 0.03 14.4 0.1 0.059 13.4 0.1 1.4 1 0 0 1 1 1 0 Kringle domain AAA_29 PF13555.1 AIO02711.1 - 0.052 13.0 0.0 0.13 11.7 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.22 AIO02711.1 - 0.095 12.9 0.0 0.23 11.7 0.0 1.6 1 0 0 1 1 1 0 ABC transporter AAA_14 PF13173.1 AIO02711.1 - 0.13 12.2 0.0 4 7.3 0.0 2.5 1 1 0 1 1 1 0 AAA domain AAA_23 PF13476.1 AIO02711.1 - 0.28 11.4 0.2 0.6 10.3 0.1 1.5 1 0 0 1 1 1 0 AAA domain CUE PF02845.11 AIO02714.1 - 0.0024 17.3 0.1 0.25 10.8 0.0 2.7 2 0 0 2 2 2 2 CUE domain Cullin_binding PF03556.10 AIO02715.1 - 9.7e-20 70.8 1.2 2.1e-19 69.7 0.8 1.5 1 0 0 1 1 1 1 Cullin binding TruD PF01142.13 AIO02719.1 - 1.6e-47 161.9 0.0 2.4e-44 151.5 0.0 3.8 2 1 0 2 2 2 2 tRNA pseudouridine synthase D (TruD) RAB3GAP2_N PF14655.1 AIO02720.1 - 9.2e-10 38.0 0.0 1.7e-09 37.2 0.0 1.4 1 0 0 1 1 1 1 Rab3 GTPase-activating protein regulatory subunit N-terminus MS_channel PF00924.13 AIO02721.1 - 1.1e-17 64.0 0.6 1.4e-17 63.6 0.4 1.1 1 0 0 1 1 1 1 Mechanosensitive ion channel Gcd10p PF04189.8 AIO02722.1 - 1.5e-69 234.4 0.0 2.2e-69 233.8 0.0 1.2 1 0 0 1 1 1 1 Gcd10p family LRR_4 PF12799.2 AIO02723.1 - 2.2e-10 39.8 0.1 0.00023 20.6 0.0 3.3 2 1 1 3 3 3 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 AIO02723.1 - 7.1e-08 32.0 0.7 0.0051 16.5 0.0 2.5 2 0 0 2 2 2 2 Leucine rich repeat LRR_1 PF00560.28 AIO02723.1 - 0.00031 20.3 0.8 0.23 11.6 0.0 3.6 3 0 0 3 3 3 1 Leucine Rich Repeat LRR_7 PF13504.1 AIO02723.1 - 0.00057 19.6 1.8 0.31 11.4 0.1 4.0 4 0 0 4 4 4 1 Leucine rich repeat LRR_9 PF14580.1 AIO02723.1 - 0.0031 17.1 0.0 0.0049 16.4 0.0 1.3 1 0 0 1 1 1 1 Leucine-rich repeat LRR_6 PF13516.1 AIO02723.1 - 0.012 15.5 1.1 0.94 9.7 0.1 3.5 3 1 0 3 3 3 0 Leucine Rich repeat CDC73 PF05179.9 AIO02725.1 - 0.013 14.8 0.0 0.023 14.0 0.0 1.3 1 0 0 1 1 1 0 RNA pol II accessory factor, Cdc73 family DUF945 PF06097.6 AIO02725.1 - 0.063 12.0 0.3 0.1 11.3 0.2 1.3 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF945) GAGA_bind PF06217.7 AIO02727.1 - 0.18 11.7 7.0 0.018 15.0 1.1 1.7 1 1 1 2 2 2 0 GAGA binding protein-like family HMG_box PF00505.14 AIO02727.1 - 0.21 11.8 3.2 0.3 11.4 0.1 2.8 3 1 0 3 3 3 0 HMG (high mobility group) box Unstab_antitox PF09720.5 AIO02727.1 - 10 5.9 9.2 6 6.6 1.7 2.7 2 0 0 2 2 2 0 Putative addiction module component HMG_box_2 PF09011.5 AIO02728.1 - 0.00012 22.3 5.4 0.0033 17.7 0.7 2.5 1 1 1 2 2 2 2 HMG-box domain YABBY PF04690.8 AIO02728.1 - 0.0018 18.5 0.9 0.0021 18.3 0.6 1.2 1 0 0 1 1 1 1 YABBY protein DUF3106 PF11304.3 AIO02728.1 - 0.0077 16.6 2.6 0.011 16.1 1.8 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3106) HMG_box PF00505.14 AIO02728.1 - 0.03 14.6 4.9 0.059 13.6 0.1 2.9 2 2 0 2 2 2 0 HMG (high mobility group) box AAA PF00004.24 AIO02730.1 - 1.1e-11 45.0 0.0 4.3e-05 23.7 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 AIO02730.1 - 6.8e-07 29.0 0.0 2.6e-06 27.1 0.0 2.0 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 AIO02730.1 - 0.0011 19.0 0.7 0.0076 16.2 0.1 2.7 1 1 0 2 2 2 1 AAA ATPase domain DUF815 PF05673.8 AIO02730.1 - 0.0058 15.5 0.0 0.019 13.8 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_14 PF13173.1 AIO02730.1 - 0.079 12.8 0.0 0.17 11.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain ComK PF06338.6 AIO02730.1 - 0.18 11.2 0.1 18 4.7 0.0 2.3 2 0 0 2 2 2 0 ComK protein Gtr1_RagA PF04670.7 AIO02732.1 - 3e-67 226.1 0.2 4e-67 225.7 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 AIO02732.1 - 3.2e-06 27.0 0.0 6.1e-06 26.1 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase Arf PF00025.16 AIO02732.1 - 6.4e-06 25.5 0.0 1.2e-05 24.5 0.0 1.4 1 0 0 1 1 1 1 ADP-ribosylation factor family YliH PF10799.3 AIO02732.1 - 0.0011 18.6 0.1 0.0035 17.0 0.0 1.8 1 0 0 1 1 1 1 Biofilm formation protein (YliH/bssR) Miro PF08477.8 AIO02732.1 - 0.003 18.0 0.0 0.013 15.9 0.0 2.0 2 0 0 2 2 2 1 Miro-like protein Pro-rich_19 PF15455.1 AIO02732.1 - 0.0059 15.6 0.0 0.0082 15.2 0.0 1.1 1 0 0 1 1 1 1 Proline-rich 19 Ras PF00071.17 AIO02732.1 - 0.0081 15.5 0.0 0.012 15.0 0.0 1.3 1 0 0 1 1 1 1 Ras family DUF910 PF06014.6 AIO02732.1 - 0.01 15.7 0.0 0.042 13.7 0.0 2.0 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF910) SRPRB PF09439.5 AIO02732.1 - 0.021 14.0 0.0 0.04 13.1 0.0 1.4 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit CDP-OH_P_transf PF01066.16 AIO02734.1 - 2.3e-16 59.9 3.5 2.3e-16 59.9 2.4 2.9 2 2 0 2 2 2 1 CDP-alcohol phosphatidyltransferase HAD_2 PF13419.1 AIO02735.1 - 2e-10 41.1 0.0 1.4e-09 38.4 0.0 2.0 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 AIO02735.1 - 0.033 14.5 0.0 0.058 13.7 0.0 1.5 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase Colicin-DNase PF12639.2 AIO02736.1 - 0.6 10.3 3.8 3.4 7.9 0.5 2.2 1 1 1 2 2 2 0 DNase/tRNase domain of colicin-like bacteriocin IncA PF04156.9 AIO02738.1 - 0.00055 19.5 9.2 0.00055 19.5 6.4 3.0 1 1 2 3 3 3 1 IncA protein Taxilin PF09728.4 AIO02738.1 - 0.051 12.6 45.1 0.067 12.2 31.3 1.1 1 0 0 1 1 1 0 Myosin-like coiled-coil protein LmjF365940-deam PF14421.1 AIO02739.1 - 4.6e-42 143.5 0.1 5.4e-22 78.1 0.0 2.3 1 1 1 2 2 2 2 A distinct subfamily of CDD/CDA-like deaminases zf-CCCH_2 PF14608.1 AIO02739.1 - 0.011 15.6 2.2 0.031 14.2 0.8 2.3 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type GDPD PF03009.12 AIO02741.1 - 3.5e-25 88.9 0.1 5.4e-25 88.3 0.1 1.3 1 1 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family PI-PLC-X PF00388.14 AIO02741.1 - 0.0063 15.9 0.2 0.021 14.2 0.1 1.9 1 1 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain Tmemb_185A PF10269.4 AIO02742.1 - 7.7e-07 28.9 24.9 0.0025 17.4 7.5 3.1 1 1 0 3 3 3 3 Transmembrane Fragile-X-F protein RRM_1 PF00076.17 AIO02743.1 - 0.0071 15.9 0.0 0.016 14.7 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) THF_DHG_CYH PF00763.18 AIO02743.1 - 0.059 13.4 0.0 13 5.8 0.0 2.3 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain SpoV PF08183.6 AIO02744.1 - 2.5e-15 55.7 0.5 4.3e-15 55.0 0.4 1.4 1 0 0 1 1 1 1 Stage V sporulation protein family Reo_sigmaC PF04582.7 AIO02745.1 - 0.03 13.5 7.7 0.38 9.8 0.6 3.3 2 1 0 3 3 3 0 Reovirus sigma C capsid protein Filament PF00038.16 AIO02746.1 - 0.33 10.3 28.2 0.46 9.9 4.4 2.9 1 1 0 2 2 2 0 Intermediate filament protein Sec8_exocyst PF04048.9 AIO02746.1 - 0.97 9.0 8.0 0.11 12.1 1.6 2.1 2 0 0 2 2 2 0 Sec8 exocyst complex component specific domain OTU PF02338.14 AIO02747.1 - 7.1e-11 42.7 0.0 2.6e-10 40.9 0.0 1.9 2 0 0 2 2 2 1 OTU-like cysteine protease DUF4223 PF13978.1 AIO02747.1 - 0.15 11.7 0.0 0.32 10.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4223) AAA_17 PF13207.1 AIO02748.1 - 7.8e-12 46.0 0.1 0.0004 21.1 0.0 3.7 3 0 0 3 3 3 2 AAA domain AAA_18 PF13238.1 AIO02748.1 - 6.7e-05 23.1 0.0 0.073 13.3 0.0 3.2 2 1 0 2 2 2 2 AAA domain AAA_33 PF13671.1 AIO02748.1 - 0.0057 16.5 6.1 0.0091 15.8 0.0 3.8 3 1 0 3 3 3 1 AAA domain YHS PF04945.8 AIO02748.1 - 0.018 14.8 10.4 0.031 14.1 0.5 3.8 4 0 0 4 4 4 0 YHS domain HTH_24 PF13412.1 AIO02748.1 - 0.046 13.1 0.0 6 6.3 0.0 2.8 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding AAA PF00004.24 AIO02748.1 - 0.076 13.2 0.0 0.93 9.7 0.0 2.5 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 AIO02748.1 - 0.12 12.4 0.0 0.12 12.4 0.0 4.9 5 0 0 5 5 5 0 AAA ATPase domain RNA_helicase PF00910.17 AIO02748.1 - 0.35 11.0 0.0 11 6.2 0.0 2.6 2 0 0 2 2 2 0 RNA helicase COG2 PF06148.6 AIO02749.1 - 6.3e-38 129.6 0.0 2e-37 128.0 0.0 1.9 1 0 0 1 1 1 1 COG (conserved oligomeric Golgi) complex component, COG2 DUF3510 PF12022.3 AIO02749.1 - 8e-18 64.7 0.0 2.6e-17 63.0 0.0 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF3510) MIF4G PF02854.14 AIO02751.1 - 2.7e-23 82.5 0.1 4.3e-23 81.8 0.1 1.3 1 0 0 1 1 1 1 MIF4G domain DUF4420 PF14390.1 AIO02751.1 - 0.043 12.6 0.0 1.8 7.3 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4420) RabGAP-TBC PF00566.13 AIO02752.1 - 6.5e-57 192.4 0.1 8.5e-57 192.0 0.1 1.1 1 0 0 1 1 1 1 Rab-GTPase-TBC domain RabGAP-TBC PF00566.13 AIO02753.1 - 3e-59 200.1 0.2 3.9e-59 199.7 0.2 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain ABC1 PF03109.11 AIO02754.1 - 7.1e-28 96.9 0.0 1.5e-27 95.9 0.0 1.6 1 0 0 1 1 1 1 ABC1 family Pkinase PF00069.20 AIO02754.1 - 1.1e-06 28.0 0.2 0.017 14.2 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 AIO02754.1 - 3.8e-06 26.1 0.0 0.0063 15.6 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.18 AIO02754.1 - 1e-05 25.4 0.0 2e-05 24.4 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.17 AIO02754.1 - 0.00059 19.2 0.0 0.0011 18.3 0.0 1.3 1 0 0 1 1 1 1 RIO1 family Apc3 PF12895.2 AIO02755.1 - 2.4e-05 24.3 6.9 0.82 9.8 0.1 4.8 4 1 1 5 5 5 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.1 AIO02755.1 - 8.4e-05 22.8 8.0 1.2 9.9 0.2 5.3 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_11 PF13414.1 AIO02755.1 - 0.0012 18.5 6.5 0.041 13.5 0.1 4.0 4 0 0 4 4 4 1 TPR repeat PPR_3 PF13812.1 AIO02755.1 - 0.0033 17.5 2.6 10 6.6 0.0 5.0 5 0 0 5 5 5 1 Pentatricopeptide repeat domain TPR_2 PF07719.12 AIO02755.1 - 0.013 15.3 12.3 4.5 7.4 0.2 6.2 7 0 0 7 7 7 0 Tetratricopeptide repeat PPR PF01535.15 AIO02755.1 - 0.091 12.7 0.0 25 5.1 0.0 3.8 4 0 0 4 4 4 0 PPR repeat TPR_7 PF13176.1 AIO02755.1 - 0.11 12.3 3.2 2.5 8.1 0.3 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_8 PF13181.1 AIO02755.1 - 0.11 12.2 0.1 6.8 6.7 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.1 AIO02755.1 - 0.18 11.7 13.3 0.87 9.5 0.5 4.8 5 1 0 5 5 5 0 Tetratricopeptide repeat TPR_4 PF07721.9 AIO02755.1 - 0.41 11.2 9.3 19 6.0 0.4 5.2 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_16 PF13432.1 AIO02755.1 - 0.63 10.7 16.6 11 6.8 0.1 5.5 5 1 1 6 6 6 0 Tetratricopeptide repeat EF-hand_7 PF13499.1 AIO02756.1 - 2.4e-13 49.9 0.3 1.3e-05 25.2 0.0 2.5 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 AIO02756.1 - 2.3e-11 42.5 4.3 0.00024 20.6 0.0 4.6 3 1 2 5 5 5 3 EF-hand domain EF-hand_8 PF13833.1 AIO02756.1 - 2.6e-10 39.7 4.6 8e-05 22.1 0.2 3.4 3 1 1 4 4 4 2 EF-hand domain pair EF-hand_1 PF00036.27 AIO02756.1 - 6.6e-10 37.5 1.3 0.00058 18.9 0.0 4.7 4 1 0 4 4 4 2 EF hand EF-hand_9 PF14658.1 AIO02756.1 - 2.6e-05 24.0 0.1 0.011 15.6 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.1 AIO02756.1 - 0.00043 19.4 0.2 1.3 8.4 0.0 3.6 3 0 0 3 3 3 2 EF hand EFhand_Ca_insen PF08726.5 AIO02756.1 - 0.032 14.1 0.1 1.3 9.0 0.0 2.3 2 0 0 2 2 2 0 Ca2+ insensitive EF hand DUF3435 PF11917.3 AIO02756.1 - 0.098 11.3 0.0 0.12 11.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3435) ATP_bind_3 PF01171.15 AIO02757.1 - 3.7e-17 62.4 0.0 6.6e-17 61.5 0.0 1.3 1 1 0 1 1 1 1 PP-loop family tRNA_Me_trans PF03054.11 AIO02757.1 - 0.012 14.1 0.0 0.025 13.1 0.0 1.5 1 1 0 1 1 1 0 tRNA methyl transferase PAPS_reduct PF01507.14 AIO02757.1 - 0.021 14.6 0.0 0.033 13.9 0.0 1.3 1 0 0 1 1 1 0 Phosphoadenosine phosphosulfate reductase family TF_Zn_Ribbon PF08271.7 AIO02757.1 - 0.53 9.6 3.0 0.76 9.1 0.1 2.4 2 0 0 2 2 2 0 TFIIB zinc-binding DUF4376 PF14301.1 AIO02758.1 - 0.054 13.6 1.9 0.15 12.2 1.3 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4376) zf-Di19 PF05605.7 AIO02758.1 - 0.15 12.1 1.8 1.6 8.9 0.3 2.6 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding Fis1_TPR_C PF14853.1 AIO02760.1 - 1.7e-05 24.5 1.6 5.9e-05 22.8 0.7 2.1 2 0 0 2 2 2 1 Fis1 C-terminal tetratricopeptide repeat TPR_1 PF00515.23 AIO02760.1 - 0.025 14.1 0.1 0.049 13.2 0.1 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_12 PF13424.1 AIO02760.1 - 0.041 13.8 0.1 0.086 12.7 0.1 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_2 PF07719.12 AIO02760.1 - 0.073 13.0 0.2 0.21 11.5 0.0 1.9 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_11 PF13414.1 AIO02760.1 - 0.081 12.5 0.1 0.17 11.5 0.1 1.5 1 0 0 1 1 1 0 TPR repeat Kelch_5 PF13854.1 AIO02762.1 - 4.5e-15 55.2 2.5 0.00053 19.8 0.0 5.3 6 0 0 6 6 6 3 Kelch motif Kelch_4 PF13418.1 AIO02762.1 - 7.5e-12 44.8 13.3 0.0021 17.7 0.2 5.5 6 0 0 6 6 6 4 Galactose oxidase, central domain Kelch_1 PF01344.20 AIO02762.1 - 2e-10 40.0 0.0 0.0075 15.7 0.0 4.7 5 0 0 5 5 5 2 Kelch motif Kelch_3 PF13415.1 AIO02762.1 - 1e-09 38.2 17.6 0.00018 21.5 0.0 6.8 7 0 0 7 7 7 4 Galactose oxidase, central domain Kelch_6 PF13964.1 AIO02762.1 - 1.4e-08 34.5 3.0 0.27 11.4 0.0 5.4 4 2 1 5 5 5 2 Kelch motif Kelch_2 PF07646.10 AIO02762.1 - 9.9e-06 25.1 1.1 1.1 9.1 0.0 5.2 5 0 0 5 5 5 2 Kelch motif Suc_Fer-like PF06999.7 AIO02763.1 - 6.5e-26 91.7 0.2 1.4e-25 90.7 0.1 1.4 1 1 0 1 1 1 1 Sucrase/ferredoxin-like PB1 PF00564.19 AIO02763.1 - 0.0096 15.5 0.0 0.019 14.6 0.0 1.4 1 0 0 1 1 1 1 PB1 domain Cuticle_3 PF11018.3 AIO02765.1 - 1 9.4 6.6 0.062 13.4 0.4 2.0 2 0 0 2 2 2 0 Pupal cuticle protein C1 Vps54 PF07928.7 AIO02766.1 - 9.9e-34 116.3 0.3 9e-30 103.5 0.1 3.6 4 0 0 4 4 4 2 Vps54-like protein GCN5L1 PF06320.8 AIO02766.1 - 0.024 14.4 0.0 0.06 13.1 0.0 1.6 1 0 0 1 1 1 0 GCN5-like protein 1 (GCN5L1) AAA_13 PF13166.1 AIO02767.1 - 1.4 7.3 8.4 3.3 6.0 5.8 1.5 1 0 0 1 1 1 0 AAA domain Rnk_N PF14760.1 AIO02767.1 - 3 7.9 11.6 1.6 8.8 0.4 3.5 3 0 0 3 3 3 0 Rnk N-terminus Arf PF00025.16 AIO02768.1 - 4.9e-60 201.7 0.0 5.5e-60 201.5 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 AIO02768.1 - 3.9e-12 45.7 0.0 4.6e-12 45.5 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Ras PF00071.17 AIO02768.1 - 4.8e-12 45.5 0.0 5.7e-12 45.3 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 AIO02768.1 - 3e-11 43.8 0.0 4.1e-11 43.4 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein G-alpha PF00503.15 AIO02768.1 - 1.9e-10 39.9 0.0 2.2e-07 29.9 0.0 2.4 1 1 1 2 2 2 2 G-protein alpha subunit MMR_HSR1 PF01926.18 AIO02768.1 - 2e-10 40.6 0.0 2.9e-10 40.1 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.5 AIO02768.1 - 2e-09 36.9 0.0 2.4e-09 36.6 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.22 AIO02768.1 - 0.00034 20.0 0.0 0.0017 17.8 0.0 1.8 1 1 0 2 2 2 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.13 AIO02768.1 - 0.0057 15.9 0.1 0.18 11.0 0.1 2.4 1 1 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.18 AIO02768.1 - 0.013 15.3 0.0 5.6 6.7 0.0 2.1 2 0 0 2 2 2 0 Dynamin family PduV-EutP PF10662.4 AIO02768.1 - 0.031 13.7 0.0 0.14 11.5 0.0 2.0 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation Thioredoxin_2 PF13098.1 AIO02768.1 - 0.11 12.7 0.0 0.14 12.3 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin-like domain AAA_28 PF13521.1 AIO02769.1 - 0.00049 20.0 0.0 0.0011 18.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain Miro PF08477.8 AIO02769.1 - 0.052 14.0 0.0 0.35 11.3 0.0 2.2 1 1 0 1 1 1 0 Miro-like protein MMR_HSR1 PF01926.18 AIO02769.1 - 0.089 12.7 0.0 0.2 11.6 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase DAP3 PF10236.4 AIO02769.1 - 0.11 11.3 0.1 0.18 10.6 0.1 1.3 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 AAA_14 PF13173.1 AIO02769.1 - 0.23 11.3 0.0 0.43 10.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain Ras PF00071.17 AIO02770.1 - 2.4e-45 153.8 0.2 3.3e-45 153.3 0.2 1.2 1 0 0 1 1 1 1 Ras family Miro PF08477.8 AIO02770.1 - 3e-16 59.9 0.0 7.6e-16 58.6 0.0 1.7 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 AIO02770.1 - 2.1e-07 30.3 0.0 3e-07 29.8 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 AIO02770.1 - 0.00036 20.0 0.3 0.015 14.7 0.2 2.2 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 AIO02770.1 - 0.00053 19.9 0.0 0.0012 18.8 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 AIO02770.1 - 0.0041 16.4 0.1 1.5 8.0 0.0 2.4 2 0 0 2 2 2 2 Ferrous iron transport protein B Gtr1_RagA PF04670.7 AIO02770.1 - 0.0076 15.4 0.2 0.034 13.2 0.0 1.9 2 0 0 2 2 2 1 Gtr1/RagA G protein conserved region PduV-EutP PF10662.4 AIO02770.1 - 0.037 13.5 0.0 0.75 9.2 0.0 2.2 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation MobB PF03205.9 AIO02770.1 - 0.07 12.8 0.0 0.16 11.6 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B SRPRB PF09439.5 AIO02770.1 - 0.093 11.9 0.0 0.17 11.0 0.0 1.5 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit DnaJ PF00226.26 AIO02771.1 - 1.5e-27 95.1 6.6 2.5e-27 94.3 4.5 1.4 1 0 0 1 1 1 1 DnaJ domain CTDII PF01556.13 AIO02771.1 - 1.3e-24 85.8 0.4 9.7e-22 76.6 0.1 2.4 2 0 0 2 2 2 2 DnaJ C terminal domain Sugar_tr PF00083.19 AIO02772.1 - 9.7e-108 360.6 37.9 5.7e-106 354.8 26.3 2.1 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 AIO02772.1 - 2.2e-18 66.1 32.5 1.1e-15 57.2 23.6 2.3 2 1 0 2 2 2 2 Major Facilitator Superfamily S-methyl_trans PF02574.11 AIO02773.1 - 2.5e-74 250.3 0.1 2.8e-74 250.1 0.0 1.0 1 0 0 1 1 1 1 Homocysteine S-methyltransferase Kelch_1 PF01344.20 AIO02773.1 - 0.0031 17.0 0.5 0.041 13.4 0.0 2.3 2 0 0 2 2 2 1 Kelch motif FliG_M PF14841.1 AIO02773.1 - 0.23 11.5 2.1 11 6.1 0.1 2.8 3 0 0 3 3 3 0 FliG middle domain FAT PF02259.18 AIO02774.1 - 7.5e-55 186.3 1.6 9.8e-55 185.9 0.2 1.9 2 0 0 2 2 2 1 FAT domain PI3_PI4_kinase PF00454.22 AIO02774.1 - 2.5e-53 180.9 0.1 4.6e-53 180.0 0.1 1.5 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase DUF3385 PF11865.3 AIO02774.1 - 2e-33 115.6 1.4 1.1e-31 109.9 0.0 4.2 6 0 0 6 6 6 1 Domain of unknown function (DUF3385) Rapamycin_bind PF08771.6 AIO02774.1 - 5.3e-28 97.0 0.2 2.2e-27 95.0 0.2 2.2 1 0 0 1 1 1 1 Rapamycin binding domain FATC PF02260.15 AIO02774.1 - 1.1e-15 56.7 0.1 1.1e-15 56.7 0.1 1.9 2 0 0 2 2 2 1 FATC domain PEX11 PF05648.9 AIO02775.1 - 0.01 15.1 0.6 0.019 14.2 0.4 1.7 1 1 0 1 1 1 0 Peroxisomal biogenesis factor 11 (PEX11) UTP15_C PF09384.5 AIO02775.1 - 0.12 12.0 0.0 0.2 11.3 0.0 1.4 1 0 0 1 1 1 0 UTP15 C terminal HECT PF00632.20 AIO02776.1 - 1.8e-55 188.3 0.0 6.1e-55 186.5 0.0 1.8 2 0 0 2 2 2 1 HECT-domain (ubiquitin-transferase) SPRY PF00622.23 AIO02776.1 - 2.4e-40 137.4 0.2 1.3e-17 64.0 0.0 4.0 3 1 0 3 3 3 3 SPRY domain Laminin_G_3 PF13385.1 AIO02776.1 - 1.6e-18 67.4 0.1 1.6e-08 34.9 0.0 3.7 5 0 0 5 5 5 2 Concanavalin A-like lectin/glucanases superfamily CAF1 PF04857.15 AIO02780.1 - 1.7e-39 135.7 0.1 2.3e-39 135.3 0.1 1.2 1 0 0 1 1 1 1 CAF1 family ribonuclease DNA_pol_A_exo1 PF01612.15 AIO02780.1 - 0.006 16.0 0.0 2.3 7.6 0.0 2.4 2 0 0 2 2 2 2 3'-5' exonuclease DUF2962 PF11176.3 AIO02781.1 - 4e-32 110.9 0.1 4e-32 110.9 0.1 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF2962) Multi_ubiq PF14452.1 AIO02781.1 - 0.066 13.1 0.2 5.9 6.9 0.0 2.8 3 0 0 3 3 3 0 Multiubiquitin Phage_B PF02304.10 AIO02781.1 - 0.78 10.0 4.5 0.45 10.8 0.6 2.2 2 0 0 2 2 2 0 Scaffold protein B RabGAP-TBC PF00566.13 AIO02782.1 - 1.2e-19 70.6 0.4 1.8e-19 70.1 0.3 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Nucleoporin_FG PF13634.1 AIO02782.1 - 0.26 11.5 46.6 0.029 14.6 20.1 2.2 1 1 1 2 2 2 0 Nucleoporin FG repeat region DUF1126 PF06565.7 AIO02783.1 - 1.1e-36 123.9 0.3 6.3e-14 51.1 0.0 3.8 3 0 0 3 3 3 3 Repeat of unknown function (DUF1126) EF-hand_8 PF13833.1 AIO02783.1 - 1.3e-06 27.8 0.5 0.027 14.0 0.0 2.9 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_7 PF13499.1 AIO02783.1 - 0.00058 19.9 0.2 0.011 15.8 0.0 2.9 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_1 PF00036.27 AIO02783.1 - 0.027 13.7 0.2 0.51 9.7 0.0 2.7 2 0 0 2 2 2 0 EF hand EF-hand_6 PF13405.1 AIO02783.1 - 0.032 14.1 0.1 17 5.6 0.0 4.1 4 0 0 4 4 4 0 EF-hand domain OST-HTH PF12872.2 AIO02783.1 - 0.1 12.4 0.0 0.25 11.2 0.0 1.6 1 0 0 1 1 1 0 OST-HTH/LOTUS domain MTHFR PF02219.12 AIO02784.1 - 7.9e-94 313.9 0.0 9.5e-94 313.6 0.0 1.0 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase Ribosomal_S8e PF01201.17 AIO02785.1 - 1.1e-34 119.4 12.8 9.4e-34 116.3 8.9 2.1 1 1 0 1 1 1 1 Ribosomal protein S8e DUF3746 PF12562.3 AIO02785.1 - 0.13 12.1 0.7 0.69 9.8 0.5 2.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3746) Peptidase_S46 PF10459.4 AIO02785.1 - 1.3 7.3 8.3 1.5 7.1 5.8 1.1 1 0 0 1 1 1 0 Peptidase S46 Tox-SHH PF15652.1 AIO02785.1 - 4.6 7.9 7.1 0.49 11.0 0.4 2.1 1 1 1 2 2 2 0 HNH/Endo VII superfamily toxin with a SHH signature DUF4496 PF14908.1 AIO02786.1 - 2e-11 43.9 0.0 4.6e-11 42.7 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4496) TB2_DP1_HVA22 PF03134.14 AIO02787.1 - 0.013 15.2 1.0 0.023 14.3 0.7 1.4 1 0 0 1 1 1 0 TB2/DP1, HVA22 family Sec23_trunk PF04811.10 AIO02788.1 - 2.2e-50 171.3 0.0 4.1e-50 170.4 0.0 1.5 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.10 AIO02788.1 - 1.2e-28 98.5 0.1 2.9e-28 97.3 0.1 1.7 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.7 AIO02788.1 - 7e-21 74.5 1.1 1.9e-20 73.1 0.7 1.8 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.10 AIO02788.1 - 1e-13 50.5 1.1 1e-13 50.5 0.8 2.0 2 0 0 2 2 2 1 Sec23/Sec24 zinc finger Gelsolin PF00626.17 AIO02788.1 - 1.6e-06 27.6 0.0 4.9e-06 26.1 0.0 1.8 1 0 0 1 1 1 1 Gelsolin repeat DUF1539 PF07560.6 AIO02789.1 - 0.16 11.8 0.7 5.5 6.8 0.0 2.2 1 1 0 2 2 2 0 Domain of Unknown Function (DUF1539) Pkinase PF00069.20 AIO02792.1 - 4.4e-63 212.8 0.0 5.4e-63 212.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AIO02792.1 - 1.1e-25 90.2 0.0 1.5e-25 89.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 AIO02792.1 - 3.1e-09 36.1 0.0 5e-09 35.5 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 AIO02792.1 - 0.00032 19.8 0.6 0.00072 18.6 0.4 1.5 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 AIO02792.1 - 0.0077 15.9 0.6 0.23 11.1 0.1 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family His_Phos_2 PF00328.17 AIO02793.1 - 1.2e-28 100.4 0.2 1.4e-25 90.3 0.1 3.0 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) His_Phos_1 PF00300.17 AIO02793.1 - 0.12 12.4 0.0 0.47 10.5 0.0 1.8 1 1 1 2 2 2 0 Histidine phosphatase superfamily (branch 1) UFD1 PF03152.9 AIO02794.1 - 6.4e-52 175.2 0.0 7.8e-52 174.9 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin fusion degradation protein UFD1 DUF2665 PF11654.3 AIO02795.1 - 0.1 12.1 0.1 2.9 7.5 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2665) PCI PF01399.22 AIO02796.1 - 0.0043 17.3 0.0 0.0084 16.4 0.0 1.5 1 0 0 1 1 1 1 PCI domain UbiA PF01040.13 AIO02798.1 - 0.0012 18.1 7.4 0.0014 17.9 5.1 1.0 1 0 0 1 1 1 1 UbiA prenyltransferase family DUF3551 PF12071.3 AIO02798.1 - 0.018 14.5 0.1 0.037 13.5 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3551) 7TMR-DISM_7TM PF07695.6 AIO02798.1 - 0.04 13.5 7.9 0.055 13.1 5.5 1.3 1 0 0 1 1 1 0 7TM diverse intracellular signalling 2TM PF13239.1 AIO02798.1 - 0.36 10.9 6.8 0.25 11.4 3.6 1.6 1 1 0 1 1 1 0 2TM domain Myb_DNA-binding PF00249.26 AIO02800.1 - 4.3e-06 26.6 0.0 7.6e-06 25.8 0.0 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 AIO02800.1 - 0.073 13.1 0.1 0.16 12.1 0.1 1.7 1 0 0 1 1 1 0 Myb-like DNA-binding domain DLH PF01738.13 AIO02801.1 - 3.6e-27 95.0 0.1 4.3e-27 94.8 0.0 1.0 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 AIO02801.1 - 3.8e-09 36.4 0.1 4.9e-09 36.0 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 AIO02801.1 - 2.1e-05 24.5 0.2 6.2e-05 22.9 0.1 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family BAAT_C PF08840.6 AIO02801.1 - 0.0042 16.8 0.0 0.0061 16.2 0.0 1.2 1 0 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal Hydrolase_4 PF12146.3 AIO02801.1 - 0.04 13.7 0.0 0.065 13.0 0.0 1.4 1 0 0 1 1 1 0 Putative lysophospholipase DUF1847 PF08901.6 AIO02801.1 - 0.1 12.1 0.0 0.25 10.8 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1847) PCMT PF01135.14 AIO02802.1 - 1.4e-47 161.9 0.0 2e-47 161.4 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_18 PF12847.2 AIO02802.1 - 6.4e-07 29.9 0.0 1.1e-06 29.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 AIO02802.1 - 0.00033 20.6 0.0 0.00052 20.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.1 AIO02802.1 - 0.00044 19.9 0.0 0.00053 19.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_24 PF13578.1 AIO02802.1 - 0.0007 20.3 0.0 0.0012 19.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain DUF4491 PF14898.1 AIO02802.1 - 0.00085 19.4 0.1 1.9 8.7 0.0 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF4491) Methyltransf_31 PF13847.1 AIO02802.1 - 0.0073 15.9 0.0 0.01 15.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 AIO02802.1 - 0.015 15.6 0.0 0.028 14.7 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_23 PF13489.1 AIO02802.1 - 0.1 12.3 0.0 0.13 12.0 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain ACBP PF00887.14 AIO02803.1 - 1.9e-16 59.4 0.0 3.7e-16 58.5 0.0 1.4 1 0 0 1 1 1 1 Acyl CoA binding protein PTCRA PF15028.1 AIO02803.1 - 0.049 13.2 0.1 0.1 12.1 0.1 1.6 1 0 0 1 1 1 0 Pre-T-cell antigen receptor Macoilin PF09726.4 AIO02804.1 - 7.9 4.6 6.5 9.2 4.4 4.5 1.1 1 0 0 1 1 1 0 Transmembrane protein NYD-SP28_assoc PF14775.1 AIO02806.1 - 4.4e-21 74.3 1.9 4.4e-21 74.3 1.3 3.3 3 0 0 3 3 3 1 Sperm tail C-terminal domain NYD-SP28 PF14772.1 AIO02806.1 - 1.7e-17 63.4 7.3 1.7e-17 63.4 5.1 5.4 4 1 1 5 5 5 2 Sperm tail RPW8 PF05659.6 AIO02806.1 - 0.00098 18.6 0.7 0.0033 16.9 0.5 1.9 1 0 0 1 1 1 1 Arabidopsis broad-spectrum mildew resistance protein RPW8 Mito_carr PF00153.22 AIO02808.1 - 1.8e-31 107.6 4.8 4.6e-12 45.4 0.0 3.1 2 1 1 3 3 3 3 Mitochondrial carrier protein KASH PF10541.4 AIO02809.1 - 0.11 12.3 0.1 0.11 12.3 0.1 4.6 5 0 0 5 5 5 0 Nuclear envelope localisation domain CSD PF00313.17 AIO02811.1 - 0.11 12.2 0.0 0.45 10.3 0.0 1.9 2 0 0 2 2 2 0 'Cold-shock' DNA-binding domain Metalloenzyme PF01676.13 AIO02812.1 - 2.4e-69 233.5 0.0 2.7e-69 233.3 0.0 1.0 1 0 0 1 1 1 1 Metalloenzyme superfamily iPGM_N PF06415.8 AIO02812.1 - 2e-62 210.4 0.0 2.9e-62 209.9 0.0 1.2 1 0 0 1 1 1 1 BPG-independent PGAM N-terminus (iPGM_N) Phosphodiest PF01663.17 AIO02812.1 - 1.2e-06 28.1 0.0 1.9e-06 27.4 0.0 1.2 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase FtsJ PF01728.14 AIO02813.1 - 1.1e-25 90.6 0.1 3.4e-25 89.0 0.0 1.8 2 0 0 2 2 2 1 FtsJ-like methyltransferase Cyt-b5 PF00173.23 AIO02814.1 - 1.6e-12 47.0 0.0 2e-12 46.7 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Spc7 PF08317.6 AIO02815.1 - 0.00078 18.2 5.6 0.00078 18.2 3.9 1.8 1 1 1 2 2 2 1 Spc7 kinetochore protein Val_tRNA-synt_C PF10458.4 AIO02815.1 - 0.0064 16.5 0.2 0.0064 16.5 0.2 3.6 3 1 0 3 3 3 1 Valyl tRNA synthetase tRNA binding arm GAS PF13851.1 AIO02815.1 - 0.1 11.7 16.3 0.14 11.3 11.3 1.1 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding ACCA PF03255.9 AIO02815.1 - 0.29 10.6 6.5 0.71 9.4 1.0 2.5 1 1 1 2 2 2 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit Halo_GVPC PF05465.8 AIO02815.1 - 0.34 10.8 2.2 2.5 8.1 0.2 2.6 2 0 0 2 2 2 0 Halobacterial gas vesicle protein C (GVPC) repeat BBP1_C PF15272.1 AIO02815.1 - 0.78 9.2 10.2 1 8.8 1.1 2.2 1 1 1 2 2 2 0 Spindle pole body component BBP1, C-terminal DUF972 PF06156.8 AIO02815.1 - 0.96 9.8 13.9 0.38 11.1 1.4 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF972) DUF812 PF05667.6 AIO02815.1 - 2.3 6.6 16.6 12 4.2 11.5 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF812) bZIP_2 PF07716.10 AIO02815.1 - 3.1 7.6 11.3 0.79 9.5 1.3 3.5 3 1 0 3 3 3 0 Basic region leucine zipper MerR-DNA-bind PF09278.6 AIO02815.1 - 3.3 8.1 14.0 17 5.8 0.2 4.1 3 1 1 4 4 4 0 MerR, DNA binding Nup54 PF13874.1 AIO02815.1 - 3.9 7.1 13.3 0.56 9.8 1.0 2.2 1 1 1 2 2 2 0 Nucleoporin complex subunit 54 YlqD PF11068.3 AIO02815.1 - 6.5 6.8 12.5 7.5 6.5 6.2 2.1 1 1 0 2 2 2 0 YlqD protein Phage_Mu_Gam PF07352.7 AIO02815.1 - 9.9 5.6 12.2 2.1 7.8 0.8 2.4 1 1 1 2 2 2 0 Bacteriophage Mu Gam like protein Solute_trans_a PF03619.11 AIO02816.1 - 1.5e-86 290.1 12.2 2e-86 289.7 8.5 1.1 1 0 0 1 1 1 1 Organic solute transporter Ostalpha DUF4064 PF13273.1 AIO02816.1 - 6.8 6.8 9.2 3 8.0 0.1 3.2 3 1 0 3 3 3 0 Protein of unknown function (DUF4064) AAA_22 PF13401.1 AIO02817.1 - 4.5e-06 26.8 0.0 1.1e-05 25.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 AIO02817.1 - 9.7e-05 22.4 0.2 0.00042 20.3 0.1 2.1 1 1 0 1 1 1 1 AAA ATPase domain AAA_19 PF13245.1 AIO02817.1 - 0.019 14.6 0.2 0.066 12.9 0.1 1.9 1 0 0 1 1 1 0 Part of AAA domain DNA_primase_S PF01896.14 AIO02817.1 - 0.032 14.0 0.0 0.099 12.4 0.0 1.7 1 1 1 2 2 2 0 Eukaryotic and archaeal DNA primase small subunit AAA_25 PF13481.1 AIO02817.1 - 0.062 12.6 0.0 0.15 11.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.1 AIO02817.1 - 0.073 13.0 0.0 0.16 11.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.1 AIO02817.1 - 0.12 12.2 0.0 0.31 10.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.1 AIO02817.1 - 0.18 12.6 0.2 0.79 10.5 0.0 2.1 2 1 0 2 2 2 0 AAA domain RecA PF00154.16 AIO02817.1 - 0.19 10.7 0.0 0.34 9.9 0.0 1.3 1 0 0 1 1 1 0 recA bacterial DNA recombination protein Rep_fac_C PF08542.6 AIO02818.1 - 2.8e-19 68.8 0.0 6.1e-19 67.7 0.0 1.6 1 0 0 1 1 1 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.1 AIO02818.1 - 2.1e-14 53.5 0.0 3.1e-14 52.9 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA PF00004.24 AIO02818.1 - 5.6e-07 29.8 0.0 1.9e-06 28.0 0.0 1.9 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activ_2 PF14532.1 AIO02818.1 - 0.00047 20.2 0.0 0.38 10.7 0.0 2.3 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_5 PF07728.9 AIO02818.1 - 0.00091 18.9 0.0 0.0051 16.5 0.0 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) Rad17 PF03215.10 AIO02818.1 - 0.0037 15.9 0.0 0.0055 15.4 0.0 1.2 1 0 0 1 1 1 1 Rad17 cell cycle checkpoint protein Mg_chelatase PF01078.16 AIO02818.1 - 0.0039 16.3 0.0 0.12 11.5 0.0 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI RuvB_N PF05496.7 AIO02818.1 - 0.0053 15.8 0.0 0.21 10.6 0.0 2.8 2 1 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 AIO02818.1 - 0.016 15.3 0.0 0.075 13.1 0.0 2.1 2 1 0 2 2 2 0 AAA domain AAA_16 PF13191.1 AIO02818.1 - 0.02 14.8 0.0 0.16 11.9 0.0 2.5 2 1 0 2 2 2 0 AAA ATPase domain Sigma54_activat PF00158.21 AIO02818.1 - 0.025 14.0 0.0 3.3 7.1 0.0 2.9 3 0 0 3 3 3 0 Sigma-54 interaction domain AAA_24 PF13479.1 AIO02818.1 - 0.029 13.9 0.0 0.053 13.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain BBIP10 PF14777.1 AIO02818.1 - 0.053 12.9 0.0 0.13 11.6 0.0 1.6 1 0 0 1 1 1 0 Cilia BBSome complex subunit 10 AAA_10 PF12846.2 AIO02818.1 - 0.11 11.9 0.0 0.24 10.8 0.0 1.6 1 1 0 1 1 1 0 AAA-like domain Peptidase_S9_N PF02897.10 AIO02821.1 - 1.9e-95 319.9 5.1 2.4e-95 319.5 3.5 1.1 1 0 0 1 1 1 1 Prolyl oligopeptidase, N-terminal beta-propeller domain Peptidase_S9 PF00326.16 AIO02821.1 - 4.5e-63 212.3 0.0 8.2e-63 211.4 0.0 1.5 1 0 0 1 1 1 1 Prolyl oligopeptidase family Esterase PF00756.15 AIO02821.1 - 0.0007 19.0 0.0 0.0014 18.0 0.0 1.5 1 0 0 1 1 1 1 Putative esterase Abhydrolase_5 PF12695.2 AIO02821.1 - 0.01 15.6 0.0 0.019 14.6 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase family DUF4019 PF13211.1 AIO02821.1 - 0.029 14.6 0.2 15 5.8 0.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF4019) Abhydrolase_3 PF07859.8 AIO02821.1 - 0.064 12.8 0.1 0.15 11.6 0.0 1.6 1 0 0 1 1 1 0 alpha/beta hydrolase fold OSCP PF00213.13 AIO02822.1 - 5.1e-07 29.7 1.2 2.4e-06 27.5 0.8 2.0 1 1 0 1 1 1 1 ATP synthase delta (OSCP) subunit Glyco_hydro_32C PF08244.7 AIO02822.1 - 0.067 13.5 0.0 0.14 12.5 0.0 1.5 1 0 0 1 1 1 0 Glycosyl hydrolases family 32 C terminal Adaptin_N PF01602.15 AIO02823.1 - 4.6e-105 351.9 2.9 5.4e-105 351.6 2.0 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.2 AIO02823.1 - 1.2e-18 67.5 0.1 5.7e-18 65.3 0.0 2.1 2 1 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.1 AIO02823.1 - 1.4e-13 50.9 0.3 4.2e-07 30.1 0.1 4.8 3 1 2 5 5 5 3 HEAT repeats HEAT PF02985.17 AIO02823.1 - 3.6e-06 26.5 9.0 0.027 14.5 0.0 5.6 6 0 0 6 6 6 2 HEAT repeat CAP18_C PF12153.3 AIO02823.1 - 0.018 14.6 0.6 0.04 13.5 0.4 1.6 1 0 0 1 1 1 0 LPS binding domain of CAP18 (C terminal) VHS PF00790.14 AIO02823.1 - 0.12 12.0 1.0 0.31 10.6 0.0 2.1 2 0 0 2 2 2 0 VHS domain Arm PF00514.18 AIO02823.1 - 0.28 11.0 1.6 39 4.2 0.1 3.9 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.1 AIO02823.1 - 0.44 11.1 8.7 1.6 9.3 0.1 4.9 5 1 0 5 5 5 0 HEAT-like repeat NIF PF03031.13 AIO02824.1 - 1.7e-31 109.0 0.0 2.4e-31 108.5 0.0 1.3 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase SET PF00856.23 AIO02825.1 - 1.4e-16 61.1 0.0 6.3e-15 55.8 0.0 2.2 1 1 0 1 1 1 1 SET domain SAF PF08666.7 AIO02825.1 - 0.039 14.3 0.0 3.1 8.2 0.0 2.4 2 0 0 2 2 2 0 SAF domain AFG1_ATPase PF03969.11 AIO02826.1 - 3e-52 177.6 1.7 8.9e-51 172.7 0.0 2.7 3 0 0 3 3 3 2 AFG1-like ATPase AAA_22 PF13401.1 AIO02826.1 - 0.03 14.4 0.6 0.49 10.5 0.0 2.9 4 1 0 4 4 4 0 AAA domain AAA_16 PF13191.1 AIO02826.1 - 0.47 10.4 3.9 0.65 9.9 0.4 2.8 3 2 0 3 3 3 0 AAA ATPase domain DUF2042 PF09743.4 AIO02827.1 - 4.1e-86 288.6 0.1 7.3e-86 287.8 0.1 1.4 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2042) NurA PF09376.5 AIO02827.1 - 0.062 12.7 0.0 0.15 11.5 0.0 1.6 1 0 0 1 1 1 0 NurA domain Baculo_p47 PF05112.7 AIO02827.1 - 0.083 12.2 0.2 0.17 11.2 0.2 1.4 1 0 0 1 1 1 0 Baculovirus P47 protein 4HBT PF03061.17 AIO02828.1 - 6.9e-05 22.8 0.0 0.0001 22.3 0.0 1.3 1 0 0 1 1 1 1 Thioesterase superfamily DUF4442 PF14539.1 AIO02828.1 - 0.00092 19.1 0.0 0.0013 18.7 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4442) SET PF00856.23 AIO02829.1 - 6.3e-08 33.0 0.0 2.8e-05 24.4 0.0 2.5 1 1 0 1 1 1 1 SET domain DUF2453 PF10507.4 AIO02830.1 - 1.4e-43 147.2 4.1 2.4e-43 146.4 2.9 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2453) EF-hand_1 PF00036.27 AIO02830.1 - 5.9e-07 28.3 0.1 0.0022 17.1 0.0 3.0 3 0 0 3 3 3 2 EF hand EF-hand_7 PF13499.1 AIO02830.1 - 7.2e-06 26.0 3.5 0.01 15.9 0.2 2.9 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_6 PF13405.1 AIO02830.1 - 0.0004 20.0 0.9 0.071 13.0 0.0 3.4 4 0 0 4 4 4 1 EF-hand domain RNA_lig_T4_1 PF09511.5 AIO02832.1 - 9.3e-15 54.7 0.0 1.9e-14 53.6 0.0 1.6 1 0 0 1 1 1 1 RNA ligase AAA_33 PF13671.1 AIO02832.1 - 1.3e-13 51.0 0.3 1.3e-13 51.0 0.2 2.1 2 0 0 2 2 2 1 AAA domain 6PF2K PF01591.13 AIO02832.1 - 3e-08 33.0 0.0 5.3e-08 32.1 0.0 1.3 1 0 0 1 1 1 1 6-phosphofructo-2-kinase AAA_18 PF13238.1 AIO02832.1 - 1.4e-05 25.4 0.0 3e-05 24.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 AIO02832.1 - 0.00039 21.2 0.0 0.00087 20.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain APS_kinase PF01583.15 AIO02832.1 - 0.00081 19.0 0.0 0.0018 17.9 0.0 1.7 1 0 0 1 1 1 1 Adenylylsulphate kinase KTI12 PF08433.5 AIO02832.1 - 0.00099 18.3 0.0 0.002 17.3 0.0 1.4 1 0 0 1 1 1 1 Chromatin associated protein KTI12 NACHT PF05729.7 AIO02832.1 - 0.0037 16.9 0.0 0.0095 15.6 0.0 1.7 1 0 0 1 1 1 1 NACHT domain RuvB_N PF05496.7 AIO02832.1 - 0.01 14.8 0.0 0.02 13.9 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 AIO02832.1 - 0.012 15.7 0.0 0.045 13.9 0.0 2.0 1 1 0 1 1 1 0 AAA domain CPT PF07931.7 AIO02832.1 - 0.018 14.6 0.6 0.051 13.2 0.2 2.0 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein Zeta_toxin PF06414.7 AIO02832.1 - 0.019 14.1 0.0 0.048 12.7 0.0 1.7 1 0 0 1 1 1 0 Zeta toxin AAA_29 PF13555.1 AIO02832.1 - 0.042 13.3 0.0 0.11 12.1 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF2070 PF09843.4 AIO02832.1 - 0.054 12.9 0.0 0.24 10.8 0.0 1.9 2 0 0 2 2 2 0 Predicted membrane protein (DUF2070) ABC_tran PF00005.22 AIO02832.1 - 0.06 13.6 0.0 0.24 11.6 0.0 2.0 2 0 0 2 2 1 0 ABC transporter AAA_5 PF07728.9 AIO02832.1 - 0.065 12.9 0.0 0.22 11.2 0.0 1.9 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_25 PF13481.1 AIO02832.1 - 0.068 12.5 0.4 0.24 10.7 0.1 1.9 1 1 1 2 2 2 0 AAA domain PRK PF00485.13 AIO02832.1 - 0.15 11.5 0.0 0.48 9.9 0.0 1.8 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family BRCA-2_OB3 PF09104.5 AIO02833.1 - 0.18 11.6 0.0 0.4 10.4 0.0 1.5 1 0 0 1 1 1 0 BRCA2, oligonucleotide/oligosaccharide-binding, domain 3 EVE PF01878.13 AIO02834.1 - 2.9e-53 179.7 0.7 3.4e-53 179.5 0.5 1.0 1 0 0 1 1 1 1 EVE domain NAGLU PF05089.7 AIO02834.1 - 0.032 13.0 0.3 0.06 12.0 0.1 1.5 1 1 1 2 2 2 0 Alpha-N-acetylglucosaminidase (NAGLU) tim-barrel domain Bromodomain PF00439.20 AIO02835.1 - 2.5e-15 56.1 0.0 4.5e-15 55.3 0.0 1.4 1 0 0 1 1 1 1 Bromodomain Med3 PF11593.3 AIO02835.1 - 0.015 14.5 1.0 0.019 14.2 0.7 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Nucleoporin_N PF08801.6 AIO02836.1 - 1.3e-45 155.9 0.0 4e-45 154.3 0.0 1.7 2 0 0 2 2 2 1 Nup133 N terminal like Nucleoporin_C PF03177.9 AIO02836.1 - 4.5e-07 28.7 1.3 1.9e-06 26.7 0.9 1.8 1 1 0 1 1 1 1 Non-repetitive/WGA-negative nucleoporin C-terminal LRR_4 PF12799.2 AIO02837.1 - 0.0012 18.3 0.0 0.06 12.9 0.0 2.5 2 0 0 2 2 2 2 Leucine Rich repeats (2 copies) Cpn60_TCP1 PF00118.19 AIO02838.1 - 4.5e-134 447.7 7.0 5.1e-134 447.5 4.9 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Ribosomal_L1 PF00687.16 AIO02839.1 - 2e-20 73.0 0.0 2.4e-20 72.8 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family DUF3633 PF12315.3 AIO02839.1 - 0.074 12.3 0.0 0.11 11.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3633) SSB PF00436.20 AIO02840.1 - 0.0027 17.5 0.0 0.0061 16.4 0.0 1.5 1 0 0 1 1 1 1 Single-strand binding protein family Flag1_repress PF03614.8 AIO02840.1 - 0.0029 17.1 0.0 0.29 10.7 0.0 2.4 2 0 0 2 2 2 1 Repressor of phase-1 flagellin zf-met PF12874.2 AIO02840.1 - 0.014 15.5 6.8 0.38 11.0 0.5 2.7 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.2 AIO02840.1 - 0.016 15.3 1.1 1.5 8.9 0.1 2.3 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) DUF629 PF04780.7 AIO02840.1 - 0.047 12.2 0.9 5 5.5 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF629) zf-C2H2 PF00096.21 AIO02840.1 - 0.054 13.8 11.7 0.51 10.7 2.5 2.6 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.3 AIO02840.1 - 0.16 12.1 5.5 5.1 7.3 0.3 2.5 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-Di19 PF05605.7 AIO02840.1 - 0.23 11.6 3.7 5.1 7.3 0.1 2.4 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_4 PF13894.1 AIO02840.1 - 0.25 11.7 8.9 1.1 9.7 0.9 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2_6 PF13912.1 AIO02840.1 - 0.48 10.3 11.0 1.4 8.9 1.3 2.4 2 0 0 2 2 2 0 C2H2-type zinc finger zf-met2 PF12907.2 AIO02840.1 - 0.61 10.0 6.2 1.5 8.8 1.1 2.5 2 0 0 2 2 2 0 Zinc-binding zf-H2C2_2 PF13465.1 AIO02840.1 - 0.86 10.0 8.3 3.7 7.9 0.2 3.4 3 0 0 3 3 3 0 Zinc-finger double domain Thioredoxin PF00085.15 AIO02842.1 - 5.2e-62 206.0 1.8 5.5e-31 106.3 0.0 3.8 4 1 0 4 4 4 3 Thioredoxin Thioredoxin_6 PF13848.1 AIO02842.1 - 1.8e-32 112.6 0.1 1.1e-18 67.7 0.0 3.4 2 1 1 3 3 3 3 Thioredoxin-like domain Thioredoxin_2 PF13098.1 AIO02842.1 - 4.6e-18 65.4 7.8 3.3e-09 36.9 0.2 5.0 3 3 1 4 4 4 2 Thioredoxin-like domain Thioredoxin_7 PF13899.1 AIO02842.1 - 3.8e-14 52.4 0.2 8.7e-07 28.8 0.0 3.4 3 0 0 3 3 3 2 Thioredoxin-like Thioredoxin_8 PF13905.1 AIO02842.1 - 2.1e-12 46.9 2.1 0.0035 17.4 0.0 5.3 4 2 2 6 6 6 3 Thioredoxin-like AhpC-TSA PF00578.16 AIO02842.1 - 6.1e-11 42.0 0.8 8.5e-05 22.2 0.0 4.0 4 0 0 4 4 4 2 AhpC/TSA family Thioredoxin_9 PF14595.1 AIO02842.1 - 2.4e-06 27.1 0.0 0.014 14.9 0.0 2.8 3 0 0 3 3 3 2 Thioredoxin Redoxin PF08534.5 AIO02842.1 - 1.1e-05 24.9 2.3 0.0036 16.8 0.0 3.3 4 0 0 4 4 4 2 Redoxin Thioredoxin_3 PF13192.1 AIO02842.1 - 4.5e-05 23.1 0.7 0.12 12.2 0.0 3.3 3 0 0 3 3 3 2 Thioredoxin domain HyaE PF07449.6 AIO02842.1 - 0.034 14.0 0.0 0.33 10.8 0.0 2.5 2 0 0 2 2 2 0 Hydrogenase-1 expression protein HyaE Sigma70_r4_2 PF08281.7 AIO02842.1 - 0.13 11.6 0.0 0.3 10.5 0.0 1.6 1 0 0 1 1 1 0 Sigma-70, region 4 FA_desaturase PF00487.19 AIO02843.1 - 9.1e-34 117.0 14.5 1.7e-33 116.1 10.0 1.4 1 0 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.23 AIO02843.1 - 1.4e-10 40.8 0.0 3.1e-10 39.6 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Methyltransf_23 PF13489.1 AIO02845.1 - 0.018 14.7 0.0 0.023 14.4 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain eIF-3c_N PF05470.7 AIO02846.1 - 5.6e-21 74.2 1.6 1.1e-15 56.8 0.0 2.3 2 1 0 2 2 2 2 Eukaryotic translation initiation factor 3 subunit 8 N-terminus PCI PF01399.22 AIO02846.1 - 0.0069 16.6 0.2 0.032 14.5 0.0 2.2 2 0 0 2 2 2 1 PCI domain 6PF2K PF01591.13 AIO02846.1 - 0.043 12.8 0.4 0.18 10.8 0.1 1.9 2 0 0 2 2 2 0 6-phosphofructo-2-kinase RRM_1 PF00076.17 AIO02847.1 - 0.0066 16.0 0.0 0.015 14.9 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 AIO02847.1 - 0.0094 15.9 0.0 0.021 14.8 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 AIO02847.1 - 0.12 12.1 0.0 0.2 11.4 0.0 1.3 1 0 0 1 1 1 0 Limkain b1 Arg_repressor_C PF02863.13 AIO02847.1 - 0.12 11.8 0.5 0.47 9.9 0.1 2.0 2 0 0 2 2 2 0 Arginine repressor, C-terminal domain RRM_5 PF13893.1 AIO02847.1 - 0.15 11.9 0.0 1 9.2 0.0 2.0 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) MOZ_SAS PF01853.13 AIO02848.1 - 2e-45 154.3 0.0 2.6e-45 154.0 0.0 1.1 1 0 0 1 1 1 1 MOZ/SAS family zf-C4_ClpX PF06689.8 AIO02848.1 - 0.0018 17.7 0.1 0.0018 17.7 0.1 1.8 2 0 0 2 2 2 1 ClpX C4-type zinc finger Acetyltransf_7 PF13508.1 AIO02848.1 - 0.0088 16.1 0.0 0.017 15.2 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 AIO02848.1 - 0.062 13.3 0.0 0.12 12.4 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family zf-C2H2_4 PF13894.1 AIO02848.1 - 0.23 11.9 1.6 0.54 10.7 1.1 1.7 1 0 0 1 1 1 0 C2H2-type zinc finger PSP1 PF04468.7 AIO02850.1 - 3.1e-30 103.9 0.1 5.3e-30 103.2 0.1 1.4 1 0 0 1 1 1 1 PSP1 C-terminal conserved region DUF3930 PF13067.1 AIO02850.1 - 0.63 9.9 2.4 3.4 7.6 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3930)