# --- full sequence ---- --- best 1 domain ---- --- domain number estimation ---- # target name accession query name accession E-value score bias E-value score bias exp reg clu ov env dom rep inc description of target #------------------- ---------- -------------------- ---------- --------- ------ ----- --------- ------ ----- --- --- --- --- --- --- --- --- --------------------- DUF2946 PF11162.8 CBZ22984.1 - 6.9e-18 65.4 1.3 1.3e-17 64.5 1.3 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2946) Shisa PF13908.6 CBZ22984.1 - 0.00015 22.1 0.0 0.00038 20.8 0.0 1.6 2 0 0 2 2 2 1 Wnt and FGF inhibitory regulator EphA2_TM PF14575.6 CBZ22984.1 - 0.0073 17.2 0.1 0.061 14.2 0.0 2.1 2 0 0 2 2 2 1 Ephrin type-A receptor 2 transmembrane domain Prominin PF05478.11 CBZ22984.1 - 0.012 13.6 1.6 0.016 13.2 1.6 1.1 1 0 0 1 1 1 0 Prominin MAP17 PF15807.5 CBZ22984.1 - 0.027 14.7 0.0 0.054 13.7 0.0 1.5 1 0 0 1 1 1 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 WBP-1 PF11669.8 CBZ22984.1 - 0.041 14.5 2.1 0.082 13.5 0.5 2.1 2 0 0 2 2 2 0 WW domain-binding protein 1 SIT PF15330.6 CBZ22984.1 - 0.049 14.1 0.0 0.16 12.4 0.0 1.8 2 0 0 2 2 2 0 SHP2-interacting transmembrane adaptor protein, SIT Hum_adeno_E3A PF05393.11 CBZ22984.1 - 0.059 13.4 1.2 0.16 12.0 1.2 1.7 1 0 0 1 1 1 0 Human adenovirus early E3A glycoprotein TMEM52 PF14979.6 CBZ22984.1 - 0.068 13.1 1.0 0.16 11.9 1.0 1.5 1 0 0 1 1 1 0 Transmembrane 52 DUF5075 PF16825.5 CBZ22984.1 - 0.068 12.9 2.1 0.13 12.0 2.1 1.4 1 0 0 1 1 1 0 IGP family C-type lectin domain Tweety PF04906.13 CBZ22984.1 - 0.51 8.9 3.5 0.27 9.9 0.5 1.8 2 0 0 2 2 2 0 Tweety ATP1G1_PLM_MAT8 PF02038.16 CBZ22984.1 - 1.1 8.8 4.9 0.64 9.5 1.5 2.1 2 0 0 2 2 2 0 ATP1G1/PLM/MAT8 family Exo_endo_phos PF03372.23 CBZ22985.1 - 6.8e-08 32.3 0.0 1.7e-07 31.0 0.0 1.7 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family TPR_21 PF09976.9 CBZ22985.1 - 0.12 12.0 2.3 0.27 10.9 2.3 1.4 1 0 0 1 1 1 0 Tetratricopeptide repeat-like domain Kinesin PF00225.23 CBZ22986.1 - 1.8e-93 313.1 0.0 2.5e-93 312.6 0.0 1.2 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 CBZ22986.1 - 7.6e-15 55.1 0.0 1.6e-14 54.1 0.0 1.6 1 0 0 1 1 1 1 Microtubule binding Dockerin_1 PF00404.18 CBZ22986.1 - 0.044 14.0 0.6 0.12 12.6 0.6 1.8 1 0 0 1 1 1 0 Dockerin type I domain Arg_decarbox_C PF17944.1 CBZ22986.1 - 0.058 14.0 1.9 0.18 12.4 0.7 2.4 2 0 0 2 2 2 0 Arginine decarboxylase C-terminal helical extension AAA_16 PF13191.6 CBZ22986.1 - 0.065 13.6 0.2 0.29 11.5 0.0 2.2 2 1 0 2 2 2 0 AAA ATPase domain BLOC1_2 PF10046.9 CBZ22986.1 - 0.53 10.6 2.7 1.8 9.0 2.7 1.9 1 1 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 GYF PF02213.16 CBZ22987.1 - 0.0019 17.8 0.2 0.0035 17.0 0.2 1.4 1 0 0 1 1 1 1 GYF domain Rotamase_3 PF13616.6 CBZ22987.1 - 0.04 14.5 0.0 0.062 13.9 0.0 1.3 1 0 0 1 1 1 0 PPIC-type PPIASE domain CPSase_L_D2 PF02786.17 CBZ22988.1 - 6.4e-77 257.8 0.5 1.2e-76 256.9 0.5 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.22 CBZ22988.1 - 7.4e-43 145.6 0.4 2.1e-42 144.2 0.1 1.9 2 0 0 2 2 2 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 CBZ22988.1 - 9.1e-36 122.3 0.0 3e-35 120.6 0.0 2.0 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.22 CBZ22988.1 - 1.5e-17 63.2 3.7 1.5e-17 63.2 3.7 2.0 2 0 0 2 2 2 1 Biotin-requiring enzyme ATP-grasp PF02222.22 CBZ22988.1 - 1.1e-08 34.8 1.0 2.7e-08 33.6 0.3 1.9 2 0 0 2 2 2 1 ATP-grasp domain PCC_BT PF18140.1 CBZ22988.1 - 4.3e-08 33.6 0.0 1.1e-07 32.2 0.0 1.7 1 0 0 1 1 1 1 Propionyl-coenzyme A carboxylase BT domain Dala_Dala_lig_C PF07478.13 CBZ22988.1 - 6.5e-06 25.8 0.3 1.5e-05 24.6 0.3 1.5 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus Biotin_lipoyl_2 PF13533.6 CBZ22988.1 - 1.8e-05 24.5 0.7 0.15 11.9 0.2 2.6 1 1 1 2 2 2 2 Biotin-lipoyl like HlyD_3 PF13437.6 CBZ22988.1 - 7.8e-05 23.3 0.5 0.055 14.2 0.1 2.6 2 0 0 2 2 2 2 HlyD family secretion protein HlyD_D23 PF16576.5 CBZ22988.1 - 0.00052 19.3 0.6 0.27 10.4 0.1 2.3 1 1 1 2 2 2 2 Barrel-sandwich domain of CusB or HlyD membrane-fusion ATP-grasp_3 PF02655.14 CBZ22988.1 - 0.0015 18.6 0.1 0.0027 17.8 0.1 1.5 1 0 0 1 1 1 1 ATP-grasp domain ATPgrasp_ST PF14397.6 CBZ22988.1 - 0.0037 16.6 0.1 0.01 15.1 0.0 1.7 2 0 0 2 2 2 1 Sugar-transfer associated ATP-grasp GARS_A PF01071.19 CBZ22988.1 - 0.0059 16.4 0.0 0.011 15.5 0.0 1.4 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain RnfC_N PF13375.6 CBZ22988.1 - 0.033 14.1 0.5 0.12 12.3 0.5 2.0 1 0 0 1 1 1 0 RnfC Barrel sandwich hybrid domain GCV_H PF01597.19 CBZ22988.1 - 0.045 13.6 1.1 0.11 12.4 1.1 1.6 1 0 0 1 1 1 0 Glycine cleavage H-protein DUF2844 PF11005.8 CBZ22988.1 - 0.11 12.6 0.0 0.34 10.9 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2844) PLC-beta_C PF08703.10 CBZ22989.1 - 0.0068 16.4 5.6 0.0068 16.4 5.6 1.4 2 0 0 2 2 2 1 PLC-beta C terminal DRY_EERY PF09750.9 CBZ22989.1 - 0.4 11.0 3.9 0.59 10.4 3.9 1.3 1 0 0 1 1 1 0 Alternative splicing regulator DltD PF04914.12 CBZ22989.1 - 0.7 9.2 1.7 0.95 8.8 1.7 1.1 1 0 0 1 1 1 0 DltD protein BSD PF03909.17 CBZ22990.1 - 1.2e-06 28.4 0.0 2.4e-06 27.4 0.0 1.5 1 0 0 1 1 1 1 BSD domain Thymidylate_kin PF02223.17 CBZ22992.1 - 7.6e-35 120.3 0.0 9.3e-35 120.0 0.0 1.1 1 0 0 1 1 1 1 Thymidylate kinase AAA_33 PF13671.6 CBZ22992.1 - 4.2e-05 23.7 0.2 0.00013 22.1 0.2 1.9 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.6 CBZ22992.1 - 0.0003 21.3 0.1 0.003 18.1 0.1 2.1 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 CBZ22992.1 - 0.0066 16.8 0.2 0.0083 16.5 0.2 1.5 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 CBZ22992.1 - 0.0077 16.5 0.0 0.016 15.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 CBZ22992.1 - 0.017 14.9 0.2 0.071 12.8 0.0 2.1 1 1 1 2 2 2 0 AAA domain TsaE PF02367.17 CBZ22992.1 - 0.019 15.0 0.0 0.042 13.8 0.0 1.6 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE DUF2075 PF09848.9 CBZ22992.1 - 0.044 13.0 0.1 0.078 12.2 0.0 1.5 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA PF00004.29 CBZ22992.1 - 0.068 13.6 0.1 0.22 11.9 0.0 1.9 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Glyco_transf_28 PF03033.20 CBZ22992.1 - 0.073 13.1 0.0 0.14 12.2 0.0 1.4 1 0 0 1 1 1 0 Glycosyltransferase family 28 N-terminal domain AAA_19 PF13245.6 CBZ22992.1 - 0.17 12.2 0.1 0.29 11.5 0.1 1.6 1 1 0 1 1 1 0 AAA domain 6PF2K PF01591.18 CBZ22992.1 - 0.21 10.9 0.0 0.35 10.1 0.0 1.3 1 0 0 1 1 1 0 6-phosphofructo-2-kinase Glyco_transf_11 PF01531.16 CBZ22993.1 - 1.6e-11 44.0 0.1 6.4e-08 32.1 0.0 2.1 2 0 0 2 2 2 2 Glycosyl transferase family 11 Glutaredoxin PF00462.24 CBZ22994.1 - 1.5e-17 63.5 0.3 2.9e-17 62.6 0.1 1.6 2 0 0 2 2 2 1 Glutaredoxin Plasmodium_Vir PF05795.11 CBZ22995.1 - 0.45 9.9 1.2 0.87 8.9 1.2 1.5 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Par3_HAL_N_term PF12053.8 CBZ22997.1 - 0.00016 21.8 0.1 0.00019 21.6 0.1 1.1 1 0 0 1 1 1 1 N-terminal of Par3 and HAL proteins LSM PF01423.22 CBZ22999.1 - 3.6e-10 39.4 0.0 4.3e-10 39.1 0.0 1.1 1 0 0 1 1 1 1 LSM domain Voltage_CLC PF00654.20 CBZ23001.1 - 2e-89 300.3 35.2 4.3e-89 299.2 30.1 2.1 2 0 0 2 2 2 2 Voltage gated chloride channel CBS PF00571.28 CBZ23001.1 - 8.9e-05 22.9 0.0 0.082 13.4 0.0 2.5 2 0 0 2 2 2 2 CBS domain cwf21 PF08312.12 CBZ23002.1 - 0.017 15.3 0.3 0.017 15.3 0.3 2.4 2 0 0 2 2 2 0 cwf21 domain Stathmin PF00836.19 CBZ23002.1 - 0.051 13.6 1.6 0.051 13.6 1.6 2.4 2 1 0 2 2 2 0 Stathmin family Aconitase_B_N PF11791.8 CBZ23002.1 - 0.088 12.9 0.5 0.97 9.5 0.0 2.5 3 0 0 3 3 3 0 Aconitate B N-terminal domain LMWPc PF01451.21 CBZ23003.1 - 1.8e-06 28.4 0.0 3e-06 27.7 0.0 1.3 1 0 0 1 1 1 1 Low molecular weight phosphotyrosine protein phosphatase CUE PF02845.16 CBZ23004.1 - 1.2e-11 44.1 0.1 0.00013 21.6 0.0 4.2 4 0 0 4 4 4 2 CUE domain Smr PF01713.21 CBZ23004.1 - 2.3e-09 37.5 0.7 6.9e-09 35.9 0.7 1.9 1 0 0 1 1 1 1 Smr domain DUF1771 PF08590.10 CBZ23004.1 - 4.3e-09 36.6 0.3 4.3e-09 36.6 0.3 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF1771) zf_CCCH_4 PF18345.1 CBZ23004.1 - 7.6e-06 25.8 25.5 0.032 14.3 4.6 4.9 4 1 0 4 4 4 4 Zinc finger domain UBA PF00627.31 CBZ23004.1 - 1.1e-05 25.2 0.1 0.012 15.5 0.1 3.1 3 0 0 3 3 3 2 UBA/TS-N domain Yeast_MT PF11403.8 CBZ23004.1 - 1.6 9.4 4.0 18 6.0 0.1 2.6 2 0 0 2 2 2 0 Yeast metallothionein Pro_isomerase PF00160.21 CBZ23005.1 - 5.6e-37 127.4 0.0 8.3e-37 126.9 0.0 1.3 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD SNF2_N PF00176.23 CBZ23007.1 - 1.7e-41 142.1 0.0 4e-41 140.9 0.0 1.5 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 CBZ23007.1 - 3.8e-15 56.2 0.0 7e-15 55.3 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 CBZ23007.1 - 3.7e-05 23.8 0.0 8.2e-05 22.7 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 CBZ23007.1 - 6.9e-05 22.7 0.0 0.00014 21.7 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_34 PF13872.6 CBZ23007.1 - 0.11 11.4 0.0 0.19 10.6 0.0 1.4 1 0 0 1 1 1 0 P-loop containing NTP hydrolase pore-1 DEAD_2 PF06733.15 CBZ23007.1 - 0.26 10.9 0.4 2.7 7.6 0.3 2.3 2 0 0 2 2 2 0 DEAD_2 Beta_helix PF13229.6 CBZ23008.1 - 1.3e-11 44.6 0.1 2.2e-10 40.6 0.2 1.7 1 1 1 2 2 2 2 Right handed beta helix region NosD PF05048.13 CBZ23008.1 - 3.9e-06 26.3 0.0 6e-06 25.7 0.0 1.1 1 0 0 1 1 1 1 Periplasmic copper-binding protein (NosD) Enkurin PF13864.6 CBZ23009.1 - 1e-19 70.8 9.0 1e-19 70.8 9.0 1.7 2 0 0 2 2 2 1 Calmodulin-binding Thioredoxin PF00085.20 CBZ23010.1 - 5.6e-20 71.3 0.0 6.6e-20 71.0 0.0 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 CBZ23010.1 - 0.00043 20.5 0.1 0.026 14.8 0.1 2.1 1 1 1 2 2 2 2 Thioredoxin-like Thioredoxin_2 PF13098.6 CBZ23010.1 - 0.0012 19.2 0.2 0.0062 17.0 0.2 1.8 1 1 0 1 1 1 1 Thioredoxin-like domain OST3_OST6 PF04756.13 CBZ23010.1 - 0.0053 16.2 0.0 0.0053 16.1 0.0 1.1 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family AhpC-TSA PF00578.21 CBZ23010.1 - 0.01 15.8 0.0 0.012 15.6 0.0 1.1 1 0 0 1 1 1 0 AhpC/TSA family HyaE PF07449.11 CBZ23010.1 - 0.023 14.7 0.0 0.034 14.1 0.0 1.2 1 0 0 1 1 1 0 Hydrogenase-1 expression protein HyaE Glutaredoxin PF00462.24 CBZ23010.1 - 0.073 13.3 0.2 0.14 12.4 0.2 1.5 1 0 0 1 1 1 0 Glutaredoxin Phosducin PF02114.16 CBZ23010.1 - 0.076 11.9 0.0 0.08 11.9 0.0 1.1 1 0 0 1 1 1 0 Phosducin PseudoU_synth_2 PF00849.22 CBZ23011.1 - 9.8e-22 77.8 0.0 2.7e-21 76.3 0.0 1.7 2 0 0 2 2 2 1 RNA pseudouridylate synthase Cmc1 PF08583.10 CBZ23012.1 - 7.3e-06 25.9 2.7 1.2e-05 25.3 2.7 1.4 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like CX9C PF16860.5 CBZ23012.1 - 0.0048 16.9 3.4 0.0094 15.9 3.4 1.5 1 0 0 1 1 1 1 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, COX17 PF05051.13 CBZ23012.1 - 0.038 14.3 0.2 0.11 12.9 0.2 1.7 1 0 0 1 1 1 0 Cytochrome C oxidase copper chaperone (COX17) UCR_hinge PF02320.16 CBZ23012.1 - 0.87 9.8 4.5 2.2 8.6 0.5 2.4 1 1 1 2 2 2 0 Ubiquinol-cytochrome C reductase hinge protein 4F5 PF04419.14 CBZ23013.1 - 1.8e-13 51.1 9.0 1.8e-13 51.1 9.0 1.8 2 0 0 2 2 2 1 4F5 protein family RSF PF14876.6 CBZ23013.1 - 0.4 9.6 1.7 0.41 9.6 1.7 1.0 1 0 0 1 1 1 0 Respiratory growth transcriptional regulator DHHA2 PF02833.14 CBZ23014.1 - 1.1e-19 71.1 0.0 3.4e-19 69.4 0.0 1.8 2 0 0 2 2 2 1 DHHA2 domain DHH PF01368.20 CBZ23014.1 - 3.2e-09 36.9 0.0 5.4e-09 36.2 0.0 1.3 1 0 0 1 1 1 1 DHH family Thoc2 PF11732.8 CBZ23014.1 - 0.11 12.5 0.0 0.33 11.0 0.0 1.8 1 1 0 1 1 1 0 Transcription- and export-related complex subunit WD40 PF00400.32 CBZ23016.1 - 7.7e-07 29.7 10.5 0.032 15.1 0.1 4.8 4 0 0 4 4 4 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBZ23016.1 - 0.022 15.0 0.0 33 4.9 0.0 3.9 3 1 2 5 5 5 0 Anaphase-promoting complex subunit 4 WD40 domain SPC25 PF06703.11 CBZ23017.1 - 0.085 12.6 0.0 0.12 12.1 0.0 1.3 1 0 0 1 1 1 0 Microsomal signal peptidase 25 kDa subunit (SPC25) MPC PF03650.13 CBZ23018.1 - 2.8e-15 56.4 0.4 3.1e-15 56.3 0.4 1.1 1 0 0 1 1 1 1 Mitochondrial pyruvate carriers T2SSM PF04612.12 CBZ23020.1 - 0.21 11.7 5.3 0.49 10.4 5.3 1.7 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein M PG_binding_3 PF09374.10 CBZ23021.1 - 0.13 12.5 0.0 0.21 11.9 0.0 1.4 1 0 0 1 1 1 0 Predicted Peptidoglycan domain TMEM208_SND2 PF05620.11 CBZ23022.1 - 2e-33 115.6 0.0 2.3e-33 115.3 0.0 1.0 1 0 0 1 1 1 1 SRP-independent targeting protein 2/TMEM208 Dymeclin PF09742.9 CBZ23023.1 - 1.8e-45 155.5 0.0 2.9e-45 154.9 0.0 1.3 1 0 0 1 1 1 1 Dyggve-Melchior-Clausen syndrome protein Hid1 PF12722.7 CBZ23023.1 - 0.0017 16.6 3.2 1 7.4 0.0 3.0 3 0 0 3 3 3 3 High-temperature-induced dauer-formation protein AAR2 PF05282.11 CBZ23023.1 - 0.64 9.4 2.4 2.1 7.6 0.0 2.5 3 0 0 3 3 3 0 AAR2 protein DUF1664 PF07889.12 CBZ23024.1 - 0.047 13.7 3.2 0.051 13.6 1.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Ribosomal_S7e PF01251.18 CBZ23026.1 - 1.8e-63 213.6 3.8 2.1e-63 213.4 3.8 1.0 1 0 0 1 1 1 1 Ribosomal protein S7e zf-UBP PF02148.19 CBZ23027.1 - 5.9e-11 42.5 9.6 2.2e-10 40.7 9.6 2.1 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein zf-RING_2 PF13639.6 CBZ23027.1 - 7e-08 32.7 7.8 7e-08 32.7 7.8 2.9 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.6 CBZ23027.1 - 2.9e-06 27.0 9.2 2.9e-06 27.0 9.2 2.6 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 CBZ23027.1 - 0.00097 18.9 16.6 0.005 16.7 3.1 2.6 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 CBZ23027.1 - 0.0014 18.8 4.7 0.0014 18.8 4.7 2.7 3 0 0 3 3 2 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 CBZ23027.1 - 0.0017 18.3 6.9 0.0017 18.3 6.9 3.0 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_11 PF17123.5 CBZ23027.1 - 0.01 15.6 6.1 0.01 15.6 6.1 2.2 2 0 0 2 2 2 0 RING-like zinc finger zf-C3HC4 PF00097.25 CBZ23027.1 - 0.016 15.1 8.3 0.016 15.1 8.3 2.6 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CBZ23027.1 - 0.053 13.6 14.4 0.023 14.7 4.7 2.7 1 1 1 2 2 2 0 RING-type zinc-finger zf-ANAPC11 PF12861.7 CBZ23027.1 - 0.067 13.2 1.6 0.23 11.6 1.6 1.9 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger DUF2852 PF11014.8 CBZ23027.1 - 0.085 13.0 2.5 4.3 7.5 0.1 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2852) RecR PF02132.15 CBZ23027.1 - 0.41 10.2 9.3 0.16 11.6 0.7 3.1 3 0 0 3 3 2 0 RecR protein NACHT_N PF17100.5 CBZ23027.1 - 0.87 9.4 8.1 0.27 11.1 0.7 2.4 1 1 1 2 2 2 0 N-terminal domain of NWD NACHT-NTPase Baculo_PP31 PF05311.11 CBZ23027.1 - 2.3 7.7 5.2 0.28 10.6 0.8 1.6 2 0 0 2 2 2 0 Baculovirus 33KDa late protein (PP31) MFS_5 PF05631.14 CBZ23028.1 - 9e-12 44.6 7.1 1.6e-06 27.3 1.3 2.5 2 1 0 2 2 2 2 Sugar-tranasporters, 12 TM DUF5558 PF17713.1 CBZ23028.1 - 0.024 15.0 0.1 0.024 15.0 0.1 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF5558) Isochorismatase PF00857.20 CBZ23029.1 - 2.8e-23 83.0 0.0 3.3e-23 82.8 0.0 1.1 1 0 0 1 1 1 1 Isochorismatase family AMP-binding PF00501.28 CBZ23031.1 - 2.4e-89 299.8 0.1 3.3e-89 299.4 0.1 1.1 1 0 0 1 1 1 1 AMP-binding enzyme Beta_elim_lyase PF01212.21 CBZ23032.1 - 1.4e-32 113.2 0.0 1.8e-32 112.8 0.0 1.1 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.19 CBZ23032.1 - 5.7e-10 38.7 0.0 7.9e-10 38.2 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.21 CBZ23032.1 - 2.3e-08 33.6 0.0 2.7e-08 33.4 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Pyridoxal_deC PF00282.19 CBZ23032.1 - 0.074 11.7 0.0 0.12 11.1 0.0 1.2 1 0 0 1 1 1 0 Pyridoxal-dependent decarboxylase conserved domain AMP-binding PF00501.28 CBZ23033.1 - 1.1e-97 327.3 0.0 1.4e-97 327.0 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding PF00501.28 CBZ23034.1 - 2.7e-80 270.1 0.0 4.6e-80 269.3 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding PF00501.28 CBZ23036.1 - 3.4e-95 319.1 0.1 4.7e-95 318.7 0.1 1.1 1 0 0 1 1 1 1 AMP-binding enzyme DUF4476 PF14771.6 CBZ23036.1 - 0.014 15.7 0.2 0.028 14.7 0.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4476) AMP-binding PF00501.28 CBZ23037.1 - 8.9e-43 146.4 0.6 7.7e-24 84.0 0.1 3.3 3 0 0 3 3 3 3 AMP-binding enzyme TPR_21 PF09976.9 CBZ23038.1 - 0.048 13.4 2.9 0.095 12.4 2.9 1.4 1 0 0 1 1 1 0 Tetratricopeptide repeat-like domain zf-CCHC_3 PF13917.6 CBZ23039.1 - 0.0032 17.4 9.8 0.0098 15.8 1.6 2.5 2 0 0 2 2 2 2 Zinc knuckle zinc-ribbons_6 PF07191.12 CBZ23039.1 - 0.085 12.9 5.9 2.3 8.3 0.6 2.2 2 0 0 2 2 2 0 zinc-ribbons zf-CCHC PF00098.23 CBZ23039.1 - 1.5 9.0 16.7 0.56 10.4 2.5 2.4 2 0 0 2 2 2 0 Zinc knuckle eIF3g PF12353.8 CBZ23039.1 - 1.6 9.1 13.2 0.9 9.9 1.5 2.4 1 1 1 2 2 2 0 Eukaryotic translation initiation factor 3 subunit G PRP3 PF08572.10 CBZ23040.1 - 1.7e-15 57.4 0.1 1.6e-14 54.2 0.1 2.2 1 1 0 1 1 1 1 pre-mRNA processing factor 3 (PRP3) DUF1115 PF06544.12 CBZ23040.1 - 5.1e-13 49.4 0.0 1.2e-12 48.2 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF1115) Mtc PF03820.17 CBZ23041.1 - 2.5e-85 286.3 0.3 2.9e-85 286.1 0.3 1.0 1 0 0 1 1 1 1 Tricarboxylate carrier RNA_ligase PF09414.10 CBZ23043.1 - 4.6e-10 40.1 0.0 7.7e-10 39.3 0.0 1.4 1 0 0 1 1 1 1 RNA ligase T4_Rnl2_C PF18043.1 CBZ23043.1 - 2.2e-06 27.7 0.0 4.3e-06 26.8 0.0 1.4 1 0 0 1 1 1 1 T4 RNA ligase 2 C-terminal RabGAP-TBC PF00566.18 CBZ23044.1 - 4.5e-25 88.6 0.0 2.8e-11 43.5 0.4 2.3 2 0 0 2 2 2 2 Rab-GTPase-TBC domain Rhodanese PF00581.20 CBZ23044.1 - 0.18 12.4 0.0 7.9 7.1 0.0 2.5 2 0 0 2 2 2 0 Rhodanese-like domain Asp_protease PF09668.10 CBZ23045.1 - 1.6e-57 192.6 0.4 2.2e-57 192.2 0.4 1.1 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 CBZ23045.1 - 7.3e-16 58.5 0.0 1.5e-15 57.5 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 CBZ23045.1 - 1e-05 26.1 0.0 2.2e-05 25.0 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease UBA_4 PF14555.6 CBZ23045.1 - 3.3e-05 23.6 0.1 5.9e-05 22.8 0.1 1.5 1 0 0 1 1 1 1 UBA-like domain RVP_2 PF08284.11 CBZ23045.1 - 0.00072 19.3 0.0 0.0011 18.7 0.0 1.2 1 0 0 1 1 1 1 Retroviral aspartyl protease RVP PF00077.20 CBZ23045.1 - 0.016 15.5 0.0 0.03 14.6 0.0 1.4 1 0 0 1 1 1 0 Retroviral aspartyl protease EF-hand_8 PF13833.6 CBZ23046.1 - 0.011 15.6 0.0 0.026 14.4 0.0 1.7 1 1 0 1 1 1 0 EF-hand domain pair EF-hand_1 PF00036.32 CBZ23046.1 - 0.18 11.4 0.0 0.64 9.7 0.0 1.9 2 0 0 2 2 2 0 EF hand HSP70 PF00012.20 CBZ23048.1 - 2.6e-29 101.9 0.4 3.4e-25 88.3 0.1 3.9 3 1 0 3 3 3 2 Hsp70 protein MreB_Mbl PF06723.13 CBZ23048.1 - 0.0039 16.1 1.4 0.0067 15.3 1.4 1.3 1 0 0 1 1 1 1 MreB/Mbl protein DUF3087 PF11286.8 CBZ23048.1 - 0.18 11.2 0.0 0.36 10.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3087) Peptidase_M16 PF00675.20 CBZ23049.1 - 1.1e-40 139.0 0.1 3.2e-40 137.6 0.0 1.7 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 CBZ23049.1 - 6e-15 55.7 0.0 2.2e-13 50.6 0.0 3.1 3 1 0 3 3 3 1 Peptidase M16 inactive domain DUF4795 PF16043.5 CBZ23049.1 - 0.18 11.4 0.0 0.41 10.2 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4795) ORC2 PF04084.14 CBZ23050.1 - 3.1e-05 23.0 0.0 0.095 11.6 0.0 2.3 2 0 0 2 2 2 2 Origin recognition complex subunit 2 Csm2_III-A PF03750.13 CBZ23052.1 - 0.16 12.8 0.0 0.29 12.0 0.0 1.3 1 0 0 1 1 1 0 Csm2 Type III-A PLAC8 PF04749.17 CBZ23053.1 - 1.9e-15 57.6 9.1 2.7e-15 57.2 9.1 1.2 1 0 0 1 1 1 1 PLAC8 family ThiF PF00899.21 CBZ23055.1 - 1e-78 264.1 0.0 1.6e-78 263.4 0.0 1.2 1 0 0 1 1 1 1 ThiF family Ldh_1_N PF00056.23 CBZ23055.1 - 0.022 14.9 0.1 0.037 14.1 0.1 1.4 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain NAD_binding_7 PF13241.6 CBZ23055.1 - 0.027 14.9 0.0 0.094 13.2 0.0 1.9 2 0 0 2 2 2 0 Putative NAD(P)-binding Sacchrp_dh_NADP PF03435.18 CBZ23055.1 - 0.048 13.9 0.1 0.098 12.9 0.1 1.5 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Shikimate_DH PF01488.20 CBZ23055.1 - 0.056 13.5 0.0 0.11 12.6 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Pyr_redox PF00070.27 CBZ23055.1 - 0.067 13.8 0.3 0.14 12.7 0.3 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase GGDEF_2 PF17853.1 CBZ23055.1 - 0.078 13.2 2.7 0.1 12.8 0.0 2.5 3 1 0 3 3 3 0 GGDEF-like domain C2 PF00168.30 CBZ23057.1 - 0.00042 20.5 0.0 0.0017 18.6 0.0 2.1 2 1 0 2 2 2 1 C2 domain DUF4478 PF14793.6 CBZ23057.1 - 0.032 14.1 0.0 0.099 12.5 0.0 1.8 1 0 0 1 1 1 0 Pyrimidine/purine nucleotide 5'-monophosphate nucleosidases Pkinase PF00069.25 CBZ23059.1 - 1.5e-20 73.7 0.0 3.5e-09 36.4 0.0 3.6 4 0 0 4 4 4 3 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ23059.1 - 0.0078 15.5 0.0 0.036 13.3 0.0 2.0 3 0 0 3 3 3 1 Protein tyrosine kinase ORC6 PF05460.13 CBZ23059.1 - 0.034 13.4 1.5 0.079 12.2 1.5 1.5 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) DEAD PF00270.29 CBZ23061.1 - 4.5e-42 143.8 0.1 1.2e-41 142.5 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CBZ23061.1 - 7.8e-29 100.3 0.3 4e-28 98.0 0.1 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain CMS1 PF14617.6 CBZ23061.1 - 6e-05 22.5 0.2 0.00017 21.0 0.0 1.7 2 0 0 2 2 2 1 U3-containing 90S pre-ribosomal complex subunit AAA_22 PF13401.6 CBZ23061.1 - 0.091 13.0 0.7 0.44 10.8 0.7 2.3 1 1 0 1 1 1 0 AAA domain ALS2CR8 PF15299.6 CBZ23063.1 - 0.013 15.4 0.1 0.023 14.6 0.1 1.3 1 0 0 1 1 1 0 Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 8 CpXC PF14353.6 CBZ23063.1 - 0.039 14.0 0.1 0.07 13.2 0.1 1.3 1 0 0 1 1 1 0 CpXC protein zf-C2H2_4 PF13894.6 CBZ23063.1 - 0.046 14.6 2.8 0.046 14.6 2.8 2.1 2 0 0 2 2 2 0 C2H2-type zinc finger Nudix_N_2 PF14803.6 CBZ23063.1 - 0.074 13.0 0.6 0.28 11.1 0.6 2.0 1 0 0 1 1 1 0 Nudix N-terminal zinc_ribbon_9 PF14369.6 CBZ23063.1 - 0.083 13.2 1.3 0.23 11.7 1.3 1.8 1 0 0 1 1 1 0 zinc-ribbon GIT_CC PF16559.5 CBZ23063.1 - 0.1 12.5 0.4 0.17 11.7 0.4 1.3 1 0 0 1 1 1 0 GIT coiled-coil Rho guanine nucleotide exchange factor RBR PF17208.3 CBZ23063.1 - 0.2 12.4 2.9 0.4 11.4 0.1 2.9 3 0 0 3 3 3 0 RNA binding Region DUF3253 PF11625.8 CBZ23063.1 - 1.4 9.2 5.2 0.6 10.4 0.6 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3253) zf-C2H2_6 PF13912.6 CBZ23063.1 - 2.2 8.4 4.3 0.71 10.0 0.8 2.0 2 0 0 2 2 2 0 C2H2-type zinc finger BK_channel_a PF03493.18 CBZ23064.1 - 7.9e-12 45.2 0.0 1.7e-11 44.2 0.0 1.5 1 0 0 1 1 1 1 Calcium-activated BK potassium channel alpha subunit Ion_trans_2 PF07885.16 CBZ23064.1 - 1.7e-10 40.7 7.7 1.8e-10 40.6 5.6 2.2 2 0 0 2 2 2 1 Ion channel Ion_trans_2 PF07885.16 CBZ23065.1 - 1.6e-11 44.0 5.7 5e-11 42.4 5.7 1.8 1 0 0 1 1 1 1 Ion channel BK_channel_a PF03493.18 CBZ23065.1 - 5.5e-07 29.7 0.0 2.1e-06 27.8 0.0 2.0 2 0 0 2 2 2 1 Calcium-activated BK potassium channel alpha subunit Peptidase_M3 PF01432.20 CBZ23066.1 - 7.2e-26 91.4 0.0 8.5e-26 91.2 0.0 1.0 1 0 0 1 1 1 1 Peptidase family M3 Cyt-b5 PF00173.28 CBZ23069.1 - 2.8e-38 129.9 0.7 7.1e-18 64.5 0.1 2.2 2 0 0 2 2 2 2 Cytochrome b5-like Heme/Steroid binding domain DUF1178 PF06676.11 CBZ23072.1 - 0.15 12.5 0.0 0.62 10.4 0.0 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1178) SelR PF01641.18 CBZ23073.1 - 0.015 15.4 0.5 0.76 9.9 0.1 2.6 2 1 0 2 2 2 0 SelR domain Xpo1 PF08389.12 CBZ23076.1 - 5.1e-25 88.3 0.3 6e-23 81.6 0.1 3.0 2 0 0 2 2 2 2 Exportin 1-like protein HEAT PF02985.22 CBZ23076.1 - 0.033 14.4 0.3 1.3e+02 3.3 0.0 4.9 4 0 0 4 4 4 0 HEAT repeat PI3_PI4_kinase PF00454.27 CBZ23077.1 - 1.3e-41 143.1 0.0 1.9e-41 142.5 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FATC PF02260.20 CBZ23077.1 - 1.4e-05 24.8 0.1 3.5e-05 23.5 0.1 1.7 1 0 0 1 1 1 1 FATC domain SF3A2 PF16835.5 CBZ23078.1 - 1.9e-23 82.7 0.0 2.9e-23 82.0 0.0 1.3 1 0 0 1 1 1 1 Pre-mRNA-splicing factor SF3a complex subunit 2 (Prp11) zf-met PF12874.7 CBZ23078.1 - 0.00061 20.1 0.2 0.0014 18.9 0.2 1.7 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 CBZ23078.1 - 0.004 17.4 0.2 0.0083 16.4 0.2 1.6 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding Ank_2 PF12796.7 CBZ23079.1 - 5.6e-08 33.3 0.0 1.6e-06 28.6 0.0 2.5 1 1 1 2 2 2 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CBZ23079.1 - 8.5e-07 29.4 0.0 0.00078 20.0 0.0 3.5 1 1 2 3 3 3 2 Ankyrin repeats (many copies) zf-C3HC4_3 PF13920.6 CBZ23079.1 - 1.2e-06 28.3 7.5 2.3e-06 27.4 7.5 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Ank_5 PF13857.6 CBZ23079.1 - 0.00038 20.7 0.0 0.0012 19.1 0.0 2.0 1 0 0 1 1 1 1 Ankyrin repeats (many copies) zf-RING_2 PF13639.6 CBZ23079.1 - 0.0024 18.2 9.7 0.0063 16.8 9.7 1.8 1 0 0 1 1 1 1 Ring finger domain Ank_3 PF13606.6 CBZ23079.1 - 0.05 14.2 0.1 1.1 10.1 0.0 3.1 3 0 0 3 3 3 0 Ankyrin repeat Vps51 PF08700.11 CBZ23080.1 - 1.2e-09 38.1 0.0 4.1e-09 36.4 0.0 1.9 2 0 0 2 2 2 1 Vps51/Vps67 Galactosyl_T PF01762.21 CBZ23081.1 - 0.02 14.7 0.1 0.064 13.1 0.0 1.9 2 0 0 2 2 2 0 Galactosyltransferase Galactosyl_T PF01762.21 CBZ23082.1 - 0.016 15.1 0.0 0.057 13.2 0.0 1.9 2 0 0 2 2 2 0 Galactosyltransferase Galactosyl_T PF01762.21 CBZ23083.1 - 0.19 11.5 0.0 0.19 11.5 0.0 2.8 4 0 0 4 4 4 0 Galactosyltransferase Galactosyl_T PF01762.21 CBZ23084.1 - 0.0066 16.3 0.1 0.015 15.1 0.0 1.7 2 0 0 2 2 2 1 Galactosyltransferase DivIC PF04977.15 CBZ23084.1 - 3.4 7.5 5.1 7 6.5 5.1 1.4 1 0 0 1 1 1 0 Septum formation initiator GlcNAc PF11397.8 CBZ23085.1 - 1.4e-136 455.6 0.0 1.9e-136 455.2 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase (GlcNAc) GlcNAc PF11397.8 CBZ23086.1 - 4e-07 29.8 0.1 0.025 14.0 0.0 2.6 2 1 0 2 2 2 2 Glycosyltransferase (GlcNAc) Ras PF00071.22 CBZ23087.1 - 4.2e-53 179.3 0.1 4.9e-53 179.0 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CBZ23087.1 - 4e-37 127.1 0.0 5.8e-37 126.6 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CBZ23087.1 - 9.8e-15 54.4 0.0 1.2e-14 54.1 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 CBZ23087.1 - 2.5e-05 23.7 0.1 3.2e-05 23.4 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 CBZ23087.1 - 0.00029 20.5 0.2 0.00066 19.3 0.2 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 CBZ23087.1 - 0.0013 18.2 0.0 0.0022 17.4 0.0 1.4 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 CBZ23087.1 - 0.002 18.2 0.0 0.0042 17.1 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 CBZ23087.1 - 0.0033 17.3 0.0 0.43 10.5 0.0 2.1 2 0 0 2 2 2 1 RsgA GTPase TniB PF05621.11 CBZ23087.1 - 0.018 14.5 0.0 0.09 12.2 0.0 1.9 2 0 0 2 2 2 0 Bacterial TniB protein ATP_bind_1 PF03029.17 CBZ23087.1 - 0.028 14.2 0.0 0.061 13.1 0.0 1.5 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein FeoB_N PF02421.18 CBZ23087.1 - 0.039 13.5 0.0 2.9 7.4 0.1 2.2 2 0 0 2 2 2 0 Ferrous iron transport protein B AAA_7 PF12775.7 CBZ23087.1 - 0.042 13.3 0.0 0.068 12.7 0.0 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_24 PF13479.6 CBZ23087.1 - 0.076 12.7 0.0 0.14 11.9 0.0 1.4 1 1 0 1 1 1 0 AAA domain PduV-EutP PF10662.9 CBZ23087.1 - 0.1 12.4 0.1 8.2 6.2 0.0 2.1 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation DUF913 PF06025.12 CBZ23087.1 - 0.16 10.9 0.0 0.21 10.5 0.0 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) DLIC PF05783.11 CBZ23087.1 - 0.32 9.8 0.0 0.32 9.8 0.0 1.7 1 1 0 2 2 2 0 Dynein light intermediate chain (DLIC) Pkinase PF00069.25 CBZ23090.1 - 2.6e-45 154.9 0.0 2.2e-44 151.8 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ23090.1 - 5.5e-29 101.2 0.0 7.4e-29 100.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CBZ23090.1 - 7.5e-07 28.7 0.0 1.1e-06 28.2 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 CBZ23090.1 - 4.7e-06 25.7 0.0 6.7e-06 25.1 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 CBZ23090.1 - 0.23 10.8 0.0 0.43 9.9 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family ABC2_membrane_3 PF12698.7 CBZ23091.1 - 8.1e-64 215.9 31.1 6.5e-40 137.3 9.5 2.2 2 0 0 2 2 2 2 ABC-2 family transporter protein ABC_tran PF00005.27 CBZ23091.1 - 2.8e-50 170.4 0.0 1.7e-25 90.1 0.0 2.5 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 CBZ23091.1 - 1e-15 58.4 8.0 6.9e-05 22.8 0.0 6.0 6 0 0 6 6 6 3 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 CBZ23091.1 - 1e-06 29.4 2.6 0.00067 20.2 0.0 2.6 3 0 0 3 3 2 2 AAA domain AAA_29 PF13555.6 CBZ23091.1 - 2e-05 24.2 0.1 0.0035 17.0 0.0 2.7 2 0 0 2 2 2 1 P-loop containing region of AAA domain SMC_N PF02463.19 CBZ23091.1 - 0.00024 20.6 0.0 4.1 6.8 0.0 3.5 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 CBZ23091.1 - 0.00065 19.6 0.1 0.011 15.6 0.0 2.3 2 0 0 2 2 2 1 RsgA GTPase ABC2_membrane PF01061.24 CBZ23091.1 - 0.0028 17.1 49.7 0.036 13.5 24.9 3.7 4 0 0 4 4 4 2 ABC-2 type transporter MMR_HSR1 PF01926.23 CBZ23091.1 - 0.028 14.5 0.2 0.57 10.3 0.0 2.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_27 PF13514.6 CBZ23091.1 - 0.034 13.8 0.6 4.2 6.9 0.0 3.3 3 0 0 3 3 3 0 AAA domain AAA_25 PF13481.6 CBZ23091.1 - 0.063 12.8 0.5 31 4.0 0.0 3.6 3 0 0 3 3 3 0 AAA domain SRP54 PF00448.22 CBZ23091.1 - 0.069 12.8 0.8 0.98 9.0 0.0 2.3 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain MukB PF04310.12 CBZ23091.1 - 0.085 12.7 0.4 5.7 6.7 0.0 2.3 2 0 0 2 2 2 0 MukB N-terminal DUF4162 PF13732.6 CBZ23091.1 - 0.12 13.1 0.0 10 7.0 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4162) DUF87 PF01935.17 CBZ23091.1 - 0.23 11.5 0.9 0.56 10.2 0.0 2.1 2 0 0 2 2 2 0 Helicase HerA, central domain LapA_dom PF06305.11 CBZ23091.1 - 2.3 8.1 4.1 7.8 6.4 2.0 3.0 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain AAA_15 PF13175.6 CBZ23091.1 - 2.6 7.6 4.4 8.9 5.9 0.0 3.3 4 0 0 4 4 4 0 AAA ATPase domain DUF2613 PF11021.8 CBZ23091.1 - 3.3 7.9 6.1 19 5.5 6.1 2.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2613) YbgS PF13985.6 CBZ23091.1 - 8.9 6.6 6.4 1.3 9.3 0.2 2.7 3 0 0 3 3 3 0 YbgS-like protein SNAP PF14938.6 CBZ23092.1 - 1.4e-11 44.3 15.6 2.1e-09 37.2 7.5 3.0 3 0 0 3 3 3 2 Soluble NSF attachment protein, SNAP DHR-2 PF06920.13 CBZ23092.1 - 0.0003 19.6 0.4 0.00042 19.1 0.4 1.1 1 0 0 1 1 1 1 Dock homology region 2 TPR_2 PF07719.17 CBZ23092.1 - 1 9.6 0.0 1 9.6 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat RNase_PH PF01138.21 CBZ23093.1 - 6.7e-18 65.5 0.0 1.4e-17 64.4 0.0 1.6 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 CBM_19 PF03427.13 CBZ23093.1 - 0.23 11.4 5.7 0.052 13.5 1.8 1.9 2 0 0 2 2 2 0 Carbohydrate binding domain (family 19) Glyco_transf_10 PF00852.19 CBZ23094.1 - 6.3e-06 26.0 0.0 1.1e-05 25.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 10 (fucosyltransferase) C-term DUF832 PF05734.11 CBZ23094.1 - 0.12 11.8 0.6 0.47 9.9 1.2 1.5 2 0 0 2 2 2 0 Herpesvirus protein of unknown function (DUF832) UAA PF08449.11 CBZ23095.1 - 7.4e-12 45.1 17.4 2.9e-09 36.6 4.9 3.4 4 0 0 4 4 4 2 UAA transporter family EamA PF00892.20 CBZ23095.1 - 0.0014 18.8 2.9 0.0014 18.8 2.9 2.6 3 0 0 3 3 3 1 EamA-like transporter family Virulence_fact PF13769.6 CBZ23096.1 - 0.022 14.9 0.6 0.057 13.7 0.6 1.6 1 0 0 1 1 1 0 Virulence factor Pkinase PF00069.25 CBZ23097.1 - 1.1e-56 192.2 0.0 1.3e-56 191.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ23097.1 - 6.8e-20 71.4 0.0 8.9e-20 71.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 CBZ23097.1 - 1.2e-05 25.4 2.2 0.00052 20.0 0.1 2.6 2 1 1 3 3 3 2 Phosphotransferase enzyme family RIO1 PF01163.22 CBZ23097.1 - 0.0031 17.1 0.1 0.0052 16.4 0.1 1.2 1 0 0 1 1 1 1 RIO1 family FTA2 PF13095.6 CBZ23097.1 - 0.055 13.1 0.0 2 8.0 0.0 2.4 3 0 0 3 3 3 0 Kinetochore Sim4 complex subunit FTA2 RPN6_N PF18055.1 CBZ23098.1 - 1.4e-29 102.8 0.0 5.7e-29 100.8 0.0 2.1 1 0 0 1 1 1 1 26S proteasome regulatory subunit RPN6 N-terminal domain PCI PF01399.27 CBZ23098.1 - 1e-11 45.3 0.2 2.5e-11 44.0 0.2 1.7 1 0 0 1 1 1 1 PCI domain TPR_19 PF14559.6 CBZ23098.1 - 0.022 15.2 10.1 1.1 9.9 0.1 4.2 5 0 0 5 5 5 0 Tetratricopeptide repeat DDRGK PF09756.9 CBZ23098.1 - 0.031 13.9 0.1 0.031 13.9 0.1 2.1 2 0 0 2 2 2 0 DDRGK domain DUF4381 PF14316.6 CBZ23098.1 - 0.075 13.3 0.9 0.18 12.0 0.9 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) TPR_20 PF14561.6 CBZ23098.1 - 0.34 11.3 6.3 30 5.1 0.0 4.4 3 1 1 4 4 4 0 Tetratricopeptide repeat FtsJ PF01728.19 CBZ23099.1 - 2.4e-64 216.7 0.0 3e-64 216.4 0.0 1.1 1 0 0 1 1 1 1 FtsJ-like methyltransferase UQ_con PF00179.26 CBZ23100.1 - 3.6e-41 140.1 0.0 4.2e-41 139.9 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 CBZ23100.1 - 0.0004 20.1 0.0 0.00048 19.8 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B zf-met PF12874.7 CBZ23102.1 - 0.1 13.0 2.9 0.3 11.5 0.2 2.8 3 0 0 3 3 3 0 Zinc-finger of C2H2 type Stevor PF17410.2 CBZ23103.1 - 0.024 14.2 0.0 0.068 12.7 0.0 1.7 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame Rhomboid PF01694.22 CBZ23104.1 - 8.6e-08 32.3 12.4 0.00033 20.7 5.7 3.1 3 1 0 3 3 3 2 Rhomboid family Porin_3 PF01459.22 CBZ23107.1 - 4.6e-06 26.3 0.0 1e-05 25.1 0.0 1.7 1 1 0 1 1 1 1 Eukaryotic porin SLX9 PF15341.6 CBZ23109.1 - 0.0066 16.8 7.3 0.044 14.2 7.3 2.3 1 1 0 1 1 1 1 Ribosome biogenesis protein SLX9 Gly_kinase PF02595.15 CBZ23111.1 - 1.2e-36 126.5 15.0 3.3e-20 72.4 0.3 6.5 6 1 0 6 6 6 5 Glycerate kinase family Kinocilin PF15033.6 CBZ23115.1 - 0.011 15.3 1.2 0.23 11.1 0.8 2.3 2 0 0 2 2 2 0 Kinocilin protein Pkinase PF00069.25 CBZ23118.1 - 1.7e-56 191.5 0.0 6.1e-51 173.3 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ23118.1 - 4e-35 121.3 0.0 3.1e-30 105.3 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 CBZ23118.1 - 0.0002 20.8 0.0 0.00077 18.9 0.0 1.8 2 0 0 2 2 2 1 Kinase-like RIO1 PF01163.22 CBZ23118.1 - 0.00088 18.9 0.0 0.002 17.7 0.0 1.5 1 0 0 1 1 1 1 RIO1 family APH PF01636.23 CBZ23118.1 - 0.0061 16.5 2.2 0.012 15.6 0.2 2.3 2 1 1 3 3 3 1 Phosphotransferase enzyme family Kdo PF06293.14 CBZ23118.1 - 0.034 13.5 0.1 0.063 12.6 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 CBZ23118.1 - 0.11 11.3 0.0 0.21 10.3 0.0 1.4 1 0 0 1 1 1 0 Fungal protein kinase ASH PF15780.5 CBZ23119.1 - 3.2e-06 27.3 4.6 0.064 13.5 0.0 6.7 8 0 0 8 8 8 2 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin Snf7 PF03357.21 CBZ23119.1 - 0.011 15.3 4.3 0.02 14.5 4.3 1.3 1 0 0 1 1 1 0 Snf7 TPR_1 PF00515.28 CBZ23120.1 - 9.8e-09 34.7 3.5 2e-07 30.5 0.8 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.6 CBZ23120.1 - 1e-07 31.5 1.1 6.8e-05 22.5 0.1 2.8 2 0 0 2 2 2 2 TPR repeat TPR_2 PF07719.17 CBZ23120.1 - 4.8e-07 29.4 9.0 1.9e-06 27.5 1.0 3.2 3 0 0 3 3 2 2 Tetratricopeptide repeat TPR_8 PF13181.6 CBZ23120.1 - 4.8e-05 23.2 1.1 0.00014 21.8 0.2 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 CBZ23120.1 - 0.013 16.3 6.0 0.081 13.8 0.2 3.7 3 0 0 3 3 2 0 Tetratricopeptide repeat TPR_7 PF13176.6 CBZ23120.1 - 0.02 14.9 3.0 1.3 9.2 0.1 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat Secretin_N_2 PF07655.13 CBZ23120.1 - 0.043 14.3 0.9 0.043 14.3 0.9 1.9 2 0 0 2 2 2 0 Secretin N-terminal domain TPR_16 PF13432.6 CBZ23120.1 - 0.058 14.1 1.5 0.058 14.1 1.5 4.9 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_9 PF13371.6 CBZ23120.1 - 1.3 9.2 11.0 0.06 13.5 1.5 3.4 4 0 0 4 4 4 0 Tetratricopeptide repeat ATG16 PF08614.11 CBZ23120.1 - 5.7 7.1 10.0 1.4 9.1 6.5 1.8 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) TPR_12 PF13424.6 CBZ23120.1 - 6.3 7.2 14.4 0.36 11.2 0.5 3.8 3 1 0 3 3 3 0 Tetratricopeptide repeat ARPC4 PF05856.12 CBZ23121.1 - 3.2e-49 166.7 0.0 3.7e-49 166.6 0.0 1.0 1 0 0 1 1 1 1 ARP2/3 complex 20 kDa subunit (ARPC4) SKA2 PF16740.5 CBZ23122.1 - 0.0003 20.5 5.8 0.0003 20.5 5.8 2.6 1 1 2 3 3 3 1 Spindle and kinetochore-associated protein 2 TACC_C PF05010.14 CBZ23122.1 - 0.21 11.4 23.0 0.28 10.9 23.0 1.1 1 0 0 1 1 1 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal ZIP4_domain PF18292.1 CBZ23122.1 - 0.31 11.0 6.4 0.067 13.1 2.0 2.0 2 0 0 2 2 2 0 Zinc transporter ZIP4 domain Sec34 PF04136.15 CBZ23122.1 - 0.33 10.8 9.0 0.15 11.9 0.4 2.8 1 1 2 3 3 3 0 Sec34-like family Jnk-SapK_ap_N PF09744.9 CBZ23122.1 - 0.72 10.1 30.5 0.067 13.4 8.7 2.1 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 DUF3584 PF12128.8 CBZ23122.1 - 1.3 6.5 23.0 1.7 6.0 23.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) EMP24_GP25L PF01105.24 CBZ23122.1 - 2.6 7.9 5.8 18 5.2 1.0 2.2 2 0 0 2 2 2 0 emp24/gp25L/p24 family/GOLD Spc7 PF08317.11 CBZ23122.1 - 3 6.6 26.3 0.079 11.8 5.1 2.1 1 1 1 2 2 2 0 Spc7 kinetochore protein FlaC_arch PF05377.11 CBZ23122.1 - 3.1 8.3 7.3 3.4 8.1 2.6 2.8 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) ACCA PF03255.14 CBZ23122.1 - 3.8 7.4 13.7 2.5 8.0 1.5 2.6 2 1 0 2 2 2 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit TMF_TATA_bd PF12325.8 CBZ23122.1 - 4.2 7.6 27.8 0.35 11.1 4.9 3.6 1 1 2 3 3 3 0 TATA element modulatory factor 1 TATA binding Prominin PF05478.11 CBZ23122.1 - 4.5 5.1 11.2 14 3.5 11.0 1.7 1 1 1 2 2 2 0 Prominin Mu-like_Pro PF10123.9 CBZ23122.1 - 7.2 6.1 15.3 19 4.7 14.8 1.8 1 1 0 1 1 1 0 Mu-like prophage I protein WD40 PF00400.32 CBZ23123.1 - 0.16 12.9 7.0 0.99 10.4 0.3 4.3 4 1 0 4 4 4 0 WD domain, G-beta repeat Aldedh PF00171.22 CBZ23124.1 - 0.0032 16.0 1.0 0.3 9.5 0.0 2.5 3 0 0 3 3 3 2 Aldehyde dehydrogenase family LRR_4 PF12799.7 CBZ23125.1 - 4.7e-11 42.7 0.0 2.6 8.6 0.0 8.0 8 1 0 9 9 9 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CBZ23125.1 - 0.00083 19.1 0.0 22 4.9 0.0 5.6 5 0 0 5 5 5 2 Leucine rich repeat SOCS PF12610.8 CBZ23125.1 - 0.21 12.0 3.9 2.3 8.7 0.0 3.7 3 0 0 3 3 3 0 Suppressor of cytokine signalling Nop14 PF04147.12 CBZ23127.1 - 2.8e-44 151.6 27.2 1.3e-33 116.3 3.8 3.1 2 1 1 3 3 3 3 Nop14-like family DUF3879 PF12995.7 CBZ23127.1 - 0.045 13.5 0.6 0.53 10.0 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function, E. rectale Gene description (DUF3879) Mito_carr PF00153.27 CBZ23128.1 - 1.1e-27 95.8 3.2 2.5e-14 53.0 0.1 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein BST2 PF16716.5 CBZ23130.1 - 1.1 9.9 12.1 6.1 7.5 9.1 2.9 3 0 0 3 3 3 0 Bone marrow stromal antigen 2 HR1 PF02185.16 CBZ23130.1 - 1.6 8.9 9.7 1.3 9.2 5.8 2.7 2 0 0 2 2 2 0 Hr1 repeat DUF948 PF06103.11 CBZ23131.1 - 0.11 12.8 0.2 0.11 12.8 0.2 8.4 5 2 4 9 9 9 0 Bacterial protein of unknown function (DUF948) KNOX2 PF03791.13 CBZ23131.1 - 0.12 11.9 2.0 3.3 7.3 0.3 3.4 2 0 0 2 2 2 0 KNOX2 domain ChaB PF06150.12 CBZ23131.1 - 1.1 9.9 10.8 1.9 9.1 1.4 4.3 3 0 0 3 3 3 0 ChaB AAA_2 PF07724.14 CBZ23132.1 - 2e-51 174.5 0.0 8.8e-49 165.9 0.0 2.8 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_lid_9 PF17871.1 CBZ23132.1 - 8.8e-33 112.3 3.7 8.8e-33 112.3 3.7 2.2 1 1 1 2 2 2 1 AAA lid domain AAA PF00004.29 CBZ23132.1 - 3.8e-24 85.6 0.6 7e-14 52.4 0.0 3.5 4 0 0 4 4 2 2 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.9 CBZ23132.1 - 1.5e-22 79.5 0.1 6.9e-22 77.3 0.1 2.3 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA_5 PF07728.14 CBZ23132.1 - 2.4e-17 63.2 0.2 6.3e-11 42.4 0.0 3.9 4 0 0 4 4 4 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 CBZ23132.1 - 6.5e-10 39.6 4.8 0.00018 21.9 0.1 4.4 3 3 2 5 5 3 2 AAA ATPase domain AAA_22 PF13401.6 CBZ23132.1 - 6.7e-08 32.9 6.1 0.0088 16.3 0.0 5.3 4 3 1 5 5 5 2 AAA domain AAA_7 PF12775.7 CBZ23132.1 - 9.6e-07 28.5 0.0 0.0061 16.1 0.0 2.9 2 1 0 2 2 2 2 P-loop containing dynein motor region Mg_chelatase PF01078.21 CBZ23132.1 - 1.6e-05 24.4 0.0 1.2 8.5 0.0 3.7 2 1 1 3 3 3 2 Magnesium chelatase, subunit ChlI AAA_18 PF13238.6 CBZ23132.1 - 3.1e-05 24.5 0.7 0.081 13.5 0.0 3.4 3 0 0 3 3 3 1 AAA domain IstB_IS21 PF01695.17 CBZ23132.1 - 5e-05 23.1 0.1 0.071 12.8 0.0 2.9 3 0 0 3 3 2 1 IstB-like ATP binding protein RNA_helicase PF00910.22 CBZ23132.1 - 5.2e-05 23.6 0.0 0.84 10.0 0.0 3.1 3 0 0 3 3 2 2 RNA helicase Sigma54_activat PF00158.26 CBZ23132.1 - 0.00018 21.3 0.0 0.14 11.9 0.0 2.8 2 1 0 2 2 2 1 Sigma-54 interaction domain DNA_pol3_delta2 PF13177.6 CBZ23132.1 - 0.00025 20.9 1.7 1.2 8.9 0.0 3.6 3 1 0 3 3 3 2 DNA polymerase III, delta subunit AAA_14 PF13173.6 CBZ23132.1 - 0.00031 20.8 0.1 0.4 10.7 0.0 3.2 3 1 0 3 3 2 1 AAA domain AAA_3 PF07726.11 CBZ23132.1 - 0.00044 20.1 0.0 0.39 10.6 0.0 3.3 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 CBZ23132.1 - 0.00047 19.9 0.1 2 8.1 0.0 3.5 3 0 0 3 3 3 1 Holliday junction DNA helicase RuvB P-loop domain NACHT PF05729.12 CBZ23132.1 - 0.00075 19.4 0.0 0.066 13.1 0.0 3.3 3 0 0 3 3 3 1 NACHT domain Roc PF08477.13 CBZ23132.1 - 0.002 18.3 0.0 1.4 9.2 0.0 2.7 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase AAA_19 PF13245.6 CBZ23132.1 - 0.0029 17.9 0.1 0.48 10.8 0.1 3.3 3 1 0 3 3 3 1 AAA domain TIP49 PF06068.13 CBZ23132.1 - 0.0033 16.7 0.3 1.1 8.3 0.0 2.7 2 1 0 2 2 2 1 TIP49 P-loop domain ResIII PF04851.15 CBZ23132.1 - 0.0044 17.1 0.8 4 7.4 0.0 3.8 3 1 1 4 4 3 1 Type III restriction enzyme, res subunit TsaE PF02367.17 CBZ23132.1 - 0.0072 16.3 0.0 3.1 7.8 0.0 2.6 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE SRP54 PF00448.22 CBZ23132.1 - 0.0073 16.0 0.0 1.4 8.5 0.0 3.2 3 0 0 3 3 3 1 SRP54-type protein, GTPase domain DUF815 PF05673.13 CBZ23132.1 - 0.0076 15.4 0.4 0.19 10.9 0.0 3.2 4 1 0 4 4 4 1 Protein of unknown function (DUF815) Ribosomal_S7 PF00177.21 CBZ23132.1 - 0.0086 15.7 0.0 0.036 13.7 0.0 2.1 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e RsgA_GTPase PF03193.16 CBZ23132.1 - 0.0091 15.9 0.0 3.7 7.4 0.0 3.0 2 0 0 2 2 2 1 RsgA GTPase AAA_33 PF13671.6 CBZ23132.1 - 0.0097 16.1 0.0 8.3 6.6 0.0 2.9 2 0 0 2 2 2 0 AAA domain ATPase_2 PF01637.18 CBZ23132.1 - 0.01 15.8 7.9 3 7.7 0.0 4.6 2 2 3 5 5 5 0 ATPase domain predominantly from Archaea AAA_28 PF13521.6 CBZ23132.1 - 0.011 16.0 0.4 3.1 8.0 0.0 3.4 4 0 0 4 4 2 0 AAA domain AAA_24 PF13479.6 CBZ23132.1 - 0.016 14.9 0.0 7.8 6.2 0.0 2.6 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.15 CBZ23132.1 - 0.024 14.6 0.1 5.3 6.9 0.0 3.1 3 0 0 3 3 2 0 NTPase ABC_tran PF00005.27 CBZ23132.1 - 0.025 15.1 1.1 9.5 6.7 0.0 3.4 3 1 0 3 3 3 0 ABC transporter AAA_23 PF13476.6 CBZ23132.1 - 0.026 15.0 11.4 23 5.4 0.0 2.9 2 1 0 2 2 2 0 AAA domain Torsin PF06309.11 CBZ23132.1 - 0.033 14.3 0.0 0.11 12.7 0.0 1.8 2 0 0 2 2 1 0 Torsin AAA_29 PF13555.6 CBZ23132.1 - 0.036 13.8 0.0 11 5.9 0.0 2.8 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_6 PF12774.7 CBZ23132.1 - 0.04 12.9 0.1 0.23 10.4 0.0 2.3 3 0 0 3 3 3 0 Hydrolytic ATP binding site of dynein motor region AAA_25 PF13481.6 CBZ23132.1 - 0.067 12.8 0.3 3.2 7.3 0.0 3.0 3 0 0 3 3 2 0 AAA domain AAA_30 PF13604.6 CBZ23132.1 - 0.072 12.8 0.3 8.2 6.1 0.0 3.4 2 1 1 3 3 3 0 AAA domain ATP_bind_1 PF03029.17 CBZ23132.1 - 0.12 12.1 0.0 5 6.8 0.0 2.6 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein TarH PF02203.15 CBZ23132.1 - 0.29 11.0 2.3 0.55 10.1 2.3 1.4 1 0 0 1 1 1 0 Tar ligand binding domain homologue DUF2347 PF09804.9 CBZ23132.1 - 0.4 10.2 2.2 0.66 9.5 2.2 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2347) AAA_17 PF13207.6 CBZ23132.1 - 1 9.8 5.7 7.5 7.0 0.0 3.9 3 1 1 4 4 3 0 AAA domain 4HB_MCP_1 PF12729.7 CBZ23132.1 - 1.4 8.5 6.3 3.4 7.2 6.3 1.6 1 0 0 1 1 1 0 Four helix bundle sensory module for signal transduction adh_short PF00106.25 CBZ23134.1 - 0.0011 18.5 0.0 0.0012 18.3 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CBZ23134.1 - 0.0026 17.3 0.0 0.0026 17.3 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Peptidase_M3 PF01432.20 CBZ23135.1 - 1.9e-135 452.7 0.0 2.5e-135 452.3 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M3 Peptidase_M50B PF13398.6 CBZ23135.1 - 0.2 11.3 0.0 0.34 10.5 0.0 1.3 1 0 0 1 1 1 0 Peptidase M50B-like LRR_4 PF12799.7 CBZ23136.1 - 7.3e-62 204.2 5.3 0.00017 21.9 0.0 16.2 11 5 4 17 17 17 16 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CBZ23136.1 - 1.3e-06 28.1 16.6 1.3 8.8 0.2 10.1 8 4 2 11 11 11 3 Leucine rich repeat LRR_5 PF13306.6 CBZ23136.1 - 2.5e-05 24.3 2.9 8 6.4 0.0 6.1 5 1 1 6 6 6 2 BspA type Leucine rich repeat region (6 copies) C1_2 PF03107.16 CBZ23136.1 - 0.16 12.4 9.0 0.43 10.9 9.0 1.8 1 0 0 1 1 1 0 C1 domain zf-RING_2 PF13639.6 CBZ23136.1 - 4.4 7.7 19.1 18 5.8 19.1 2.2 1 0 0 1 1 1 0 Ring finger domain 2-Hacid_dh_C PF02826.19 CBZ23138.1 - 9.5e-55 184.7 0.1 1.4e-54 184.2 0.1 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 CBZ23138.1 - 1.4e-33 115.4 0.0 1.8e-33 115.1 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 CBZ23138.1 - 3.9e-06 27.1 0.2 2.6e-05 24.4 0.3 2.1 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase AdoHcyase_NAD PF00670.21 CBZ23138.1 - 0.00084 19.4 0.5 0.0017 18.4 0.5 1.4 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain XdhC_C PF13478.6 CBZ23138.1 - 0.003 18.1 0.0 0.0059 17.1 0.0 1.5 1 0 0 1 1 1 1 XdhC Rossmann domain IlvN PF07991.12 CBZ23138.1 - 0.016 14.8 0.1 0.04 13.5 0.1 1.7 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain AlaDh_PNT_C PF01262.21 CBZ23138.1 - 0.11 11.8 1.5 3 7.1 1.5 2.4 1 1 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Aminotran_5 PF00266.19 CBZ23139.1 - 6.3e-21 74.8 0.0 7.3e-21 74.5 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-V Rep_fac-A_3 PF08661.11 CBZ23139.1 - 0.092 13.1 0.0 14 6.1 0.0 2.4 2 0 0 2 2 2 0 Replication factor A protein 3 Met_10 PF02475.16 CBZ23140.1 - 2.1e-41 141.9 0.0 4.2e-38 131.1 0.0 2.1 2 0 0 2 2 2 2 Met-10+ like-protein Methyltransf_15 PF09445.10 CBZ23140.1 - 3.8e-05 23.3 0.0 6e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase MTS PF05175.14 CBZ23140.1 - 4.3e-05 23.1 0.0 6.7e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.6 CBZ23140.1 - 0.0035 18.0 0.0 0.015 16.0 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain tRNA_U5-meth_tr PF05958.11 CBZ23140.1 - 0.0053 15.8 0.0 0.0088 15.1 0.0 1.3 1 0 0 1 1 1 1 tRNA (Uracil-5-)-methyltransferase Methyltransf_31 PF13847.6 CBZ23140.1 - 0.038 13.8 0.0 0.062 13.1 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase domain FWWh PF14922.6 CBZ23141.1 - 0.089 12.7 0.1 0.34 10.8 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function Acyltransferase PF01553.21 CBZ23142.1 - 5.4e-12 45.5 0.0 2.6e-11 43.3 0.0 2.0 1 1 0 1 1 1 1 Acyltransferase ATP-synt_D PF01813.17 CBZ23142.1 - 0.011 15.6 0.2 0.021 14.7 0.2 1.4 1 0 0 1 1 1 0 ATP synthase subunit D HopW1-1 PF15457.6 CBZ23142.1 - 0.22 10.8 0.0 0.32 10.2 0.0 1.2 1 0 0 1 1 1 0 Type III T3SS secreted effector HopW1-1/HopPmaA PrgI PF12666.7 CBZ23142.1 - 3.5 8.4 6.9 14 6.5 0.2 2.5 2 0 0 2 2 2 0 PrgI family protein DNA_primase_lrg PF04104.14 CBZ23143.1 - 4.2e-81 272.2 0.0 5.6e-81 271.8 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic and archaeal DNA primase, large subunit CtaG_Cox11 PF04442.14 CBZ23144.1 - 3.9e-43 147.1 0.1 4.4e-43 146.9 0.1 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein CtaG/Cox11 CH PF00307.31 CBZ23145.1 - 0.028 14.6 0.0 0.13 12.4 0.0 2.0 2 0 0 2 2 2 0 Calponin homology (CH) domain RNase_H2-Ydr279 PF09468.10 CBZ23145.1 - 0.06 13.5 0.4 0.14 12.3 0.4 1.6 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) wHTH domain LRR_8 PF13855.6 CBZ23146.1 - 3.6e-10 39.4 16.4 9.8e-05 22.0 2.5 3.8 4 0 0 4 4 4 3 Leucine rich repeat LRR_4 PF12799.7 CBZ23146.1 - 1.4e-09 38.0 16.1 0.0014 19.0 1.0 4.3 3 1 1 4 4 4 4 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 CBZ23146.1 - 3.7e-09 36.3 4.2 1e-06 28.3 1.1 2.3 1 1 1 2 2 2 2 Leucine-rich repeat TMF_TATA_bd PF12325.8 CBZ23146.1 - 0.014 15.6 11.0 0.032 14.5 11.0 1.6 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding LRR_6 PF13516.6 CBZ23146.1 - 0.017 15.1 5.1 1.3 9.3 0.1 4.3 3 1 1 4 4 4 0 Leucine Rich repeat FAM76 PF16046.5 CBZ23146.1 - 0.02 14.3 0.7 0.28 10.5 0.3 2.4 2 0 0 2 2 2 0 FAM76 protein Dynactin_p62 PF05502.13 CBZ23146.1 - 0.026 13.3 0.5 0.043 12.6 0.5 1.3 1 0 0 1 1 1 0 Dynactin p62 family DUF4530 PF15039.6 CBZ23146.1 - 0.028 14.6 2.2 0.092 12.9 2.2 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4530) Tup_N PF08581.10 CBZ23146.1 - 0.055 13.8 6.4 3.1 8.2 0.7 2.8 2 0 0 2 2 2 0 Tup N-terminal Spc7 PF08317.11 CBZ23146.1 - 0.066 12.1 10.6 0.11 11.3 10.6 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein CR6_interact PF10147.9 CBZ23146.1 - 0.24 11.1 7.2 0.18 11.5 5.2 1.8 1 1 0 1 1 1 0 Growth arrest and DNA-damage-inducible proteins-interacting protein 1 TACC_C PF05010.14 CBZ23146.1 - 0.3 10.9 7.0 0.52 10.1 7.0 1.4 1 0 0 1 1 1 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal UPF0449 PF15136.6 CBZ23146.1 - 0.47 11.0 3.5 6.7 7.2 0.1 3.0 2 0 0 2 2 2 0 Uncharacterised protein family UPF0449 YabA PF06156.13 CBZ23146.1 - 0.74 10.5 3.3 1.8 9.3 3.3 1.7 1 0 0 1 1 1 0 Initiation control protein YabA Filament PF00038.21 CBZ23146.1 - 0.84 9.2 12.1 2.4 7.7 12.1 1.8 1 1 0 1 1 1 0 Intermediate filament protein COG2 PF06148.11 CBZ23146.1 - 2 8.5 4.4 2.8 8.0 3.2 1.9 1 1 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 HALZ PF02183.18 CBZ23146.1 - 2.7 8.3 8.5 3.7 7.8 0.4 3.1 3 1 0 3 3 2 0 Homeobox associated leucine zipper Acetyltransf_1 PF00583.25 CBZ23147.1 - 1.2e-07 32.0 0.0 1.6e-07 31.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 CBZ23147.1 - 1.1e-06 28.5 0.1 1.5e-06 28.2 0.1 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 CBZ23147.1 - 1.8e-06 28.3 0.1 2.5e-06 27.8 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_15 PF17013.5 CBZ23147.1 - 0.0052 16.3 1.2 0.0071 15.8 1.2 1.3 1 0 0 1 1 1 1 Putative acetyl-transferase Acetyltransf_9 PF13527.7 CBZ23147.1 - 0.0052 16.9 0.1 0.01 15.9 0.1 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain DUF4558 PF15104.6 CBZ23148.1 - 0.00032 20.7 2.3 0.00032 20.7 2.3 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF4558) ABC_tran PF00005.27 CBZ23150.1 - 1.1e-46 158.8 4.8 1.7e-22 80.4 0.0 3.7 4 0 0 4 4 3 2 ABC transporter ABC_tran_Xtn PF12848.7 CBZ23150.1 - 9.2e-25 86.5 4.6 9.2e-25 86.5 4.6 3.2 4 0 0 4 4 3 1 ABC transporter AAA_21 PF13304.6 CBZ23150.1 - 1.1e-17 64.9 8.6 0.00019 21.4 0.5 4.3 3 1 0 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 CBZ23150.1 - 2.4e-11 43.5 1.2 0.0037 16.7 0.1 4.3 2 2 1 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 CBZ23150.1 - 7.6e-08 32.9 0.1 0.02 15.3 0.1 2.9 2 0 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.6 CBZ23150.1 - 2.1e-07 30.6 0.4 0.0081 15.9 0.0 3.0 3 0 0 3 3 2 2 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 CBZ23150.1 - 3.6e-07 30.3 0.3 0.023 14.8 0.1 3.1 3 0 0 3 3 2 2 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 CBZ23150.1 - 1.3e-06 28.4 0.2 0.012 15.5 0.0 2.6 2 0 0 2 2 2 2 RsgA GTPase AAA_15 PF13175.6 CBZ23150.1 - 3.6e-06 26.9 5.1 0.13 12.0 0.1 4.3 3 1 0 4 4 4 2 AAA ATPase domain AAA_28 PF13521.6 CBZ23150.1 - 4.9e-05 23.6 4.4 0.02 15.2 0.1 3.7 4 0 0 4 4 4 2 AAA domain AAA_30 PF13604.6 CBZ23150.1 - 5.1e-05 23.1 0.0 0.28 10.9 0.0 2.9 2 0 0 2 2 2 2 AAA domain AAA_33 PF13671.6 CBZ23150.1 - 5.6e-05 23.3 4.9 0.28 11.3 0.0 3.8 2 1 0 3 3 3 2 AAA domain NACHT PF05729.12 CBZ23150.1 - 6.8e-05 22.8 0.1 0.57 10.1 0.0 2.8 3 0 0 3 3 2 2 NACHT domain AAA_23 PF13476.6 CBZ23150.1 - 7.8e-05 23.3 14.0 0.027 14.9 0.0 4.3 5 0 0 5 5 4 2 AAA domain AAA_22 PF13401.6 CBZ23150.1 - 0.00041 20.6 1.6 0.26 11.5 0.1 3.4 2 2 0 2 2 2 1 AAA domain Roc PF08477.13 CBZ23150.1 - 0.00065 19.9 0.0 2.2 8.5 0.0 2.8 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase AAA_24 PF13479.6 CBZ23150.1 - 0.00068 19.4 0.6 1.4 8.6 0.0 3.2 3 0 0 3 3 3 2 AAA domain AAA PF00004.29 CBZ23150.1 - 0.001 19.5 0.1 1.3 9.5 0.0 3.4 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 CBZ23150.1 - 0.0012 19.4 4.8 0.057 14.0 0.0 3.5 4 0 0 4 4 3 1 AAA domain RNA_helicase PF00910.22 CBZ23150.1 - 0.0022 18.4 0.0 0.72 10.3 0.0 2.9 2 0 0 2 2 2 1 RNA helicase AAA_5 PF07728.14 CBZ23150.1 - 0.0028 17.7 0.1 2.6 8.0 0.0 3.0 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_25 PF13481.6 CBZ23150.1 - 0.0029 17.2 0.1 3.4 7.2 0.0 2.9 2 0 0 2 2 2 2 AAA domain TsaE PF02367.17 CBZ23150.1 - 0.0044 17.0 0.1 0.89 9.6 0.0 2.7 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_14 PF13173.6 CBZ23150.1 - 0.0054 16.8 0.1 7.9 6.5 0.0 3.5 3 1 1 4 4 3 0 AAA domain PduV-EutP PF10662.9 CBZ23150.1 - 0.0066 16.2 0.1 0.25 11.1 0.0 2.6 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation Dynamin_N PF00350.23 CBZ23150.1 - 0.016 15.3 4.8 6.9 6.7 0.0 4.1 4 1 0 4 4 4 0 Dynamin family SRP54 PF00448.22 CBZ23150.1 - 0.022 14.4 0.3 5.4 6.6 0.0 2.6 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_7 PF12775.7 CBZ23150.1 - 0.026 14.0 0.1 2 7.9 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region FeoB_N PF02421.18 CBZ23150.1 - 0.027 14.0 0.1 1.5 8.3 0.1 2.4 2 0 0 2 2 2 0 Ferrous iron transport protein B cobW PF02492.19 CBZ23150.1 - 0.035 13.7 0.1 1.5 8.4 0.0 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Arf PF00025.21 CBZ23150.1 - 0.041 13.3 1.5 2.1 7.8 0.0 3.2 4 0 0 4 4 4 0 ADP-ribosylation factor family NTPase_1 PF03266.15 CBZ23150.1 - 0.077 12.9 1.2 13 5.6 0.1 3.3 4 0 0 4 4 2 0 NTPase MukB PF04310.12 CBZ23150.1 - 0.083 12.7 0.1 4.9 6.9 0.0 2.5 2 0 0 2 2 2 0 MukB N-terminal Ploopntkinase3 PF18751.1 CBZ23150.1 - 0.088 12.7 0.0 3.8 7.4 0.0 2.7 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 MeaB PF03308.16 CBZ23150.1 - 0.092 11.7 0.1 7 5.5 0.0 2.6 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB ATP_bind_1 PF03029.17 CBZ23150.1 - 0.16 11.7 2.1 21 4.8 0.2 3.4 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein AAA_27 PF13514.6 CBZ23150.1 - 1.5 8.3 6.0 6.2 6.3 0.0 3.3 4 0 0 4 4 3 0 AAA domain Septin PF00735.18 CBZ23150.1 - 2.8 7.2 7.5 2.5 7.3 0.0 3.0 4 0 0 4 4 3 0 Septin zf-C2H2_3 PF13878.6 CBZ23152.1 - 1.7e-11 43.7 0.1 4.3e-11 42.5 0.1 1.7 1 0 0 1 1 1 1 zinc-finger of acetyl-transferase ESCO zf-CCCH PF00642.24 CBZ23153.1 - 1.9e-08 34.0 7.9 5.7e-05 22.9 1.2 2.7 3 0 0 3 3 3 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 CBZ23153.1 - 6.9e-08 32.3 6.8 0.0032 17.5 2.0 2.8 2 0 0 2 2 2 2 Zinc finger domain RRM_1 PF00076.22 CBZ23153.1 - 1.8e-06 27.6 0.0 3.5e-05 23.5 0.0 2.6 2 1 1 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Torus PF16131.5 CBZ23153.1 - 0.0049 17.6 9.0 0.077 13.7 0.3 2.7 2 1 1 3 3 3 2 Torus domain Herpes_UL87 PF03043.14 CBZ23153.1 - 0.034 12.6 0.1 0.046 12.2 0.1 1.1 1 0 0 1 1 1 0 Herpesvirus UL87 family zf-CCCH_4 PF18044.1 CBZ23153.1 - 0.24 11.3 11.6 0.13 12.1 1.5 2.8 2 1 0 2 2 2 0 CCCH-type zinc finger zf-CCCH_2 PF14608.6 CBZ23153.1 - 0.36 11.4 3.7 20 5.8 0.5 2.7 2 1 0 2 2 2 0 RNA-binding, Nab2-type zinc finger Aldedh PF00171.22 CBZ23154.1 - 3.3e-106 355.6 0.0 3.9e-106 355.3 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF35_N PF12172.8 CBZ23154.1 - 0.15 12.0 0.4 3.7 7.5 0.7 2.4 2 0 0 2 2 2 0 Rubredoxin-like zinc ribbon domain (DUF35_N) Pkinase PF00069.25 CBZ23155.1 - 7.7e-42 143.5 0.0 1e-41 143.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ23155.1 - 1.4e-19 70.4 0.0 2.4e-19 69.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CBZ23155.1 - 7e-05 21.8 0.0 9.6e-05 21.3 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 CBZ23155.1 - 0.00095 18.2 0.1 0.0015 17.6 0.1 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 CBZ23155.1 - 0.0057 16.0 0.0 0.0095 15.3 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 CBZ23155.1 - 0.04 13.5 0.0 0.058 13.0 0.0 1.3 1 0 0 1 1 1 0 RIO1 family Kinase-like PF14531.6 CBZ23155.1 - 0.088 12.1 0.0 0.19 11.0 0.0 1.5 1 1 0 1 1 1 0 Kinase-like AMP-binding PF00501.28 CBZ23157.1 - 6e-89 298.5 0.0 8e-89 298.1 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme Ribosomal_L38e PF01781.18 CBZ23159.1 - 2.9e-29 101.0 4.0 3.4e-29 100.7 4.0 1.1 1 0 0 1 1 1 1 Ribosomal L38e protein family Retrotran_gag_2 PF14223.6 CBZ23160.1 - 0.069 12.8 0.3 0.28 10.8 0.3 1.8 2 0 0 2 2 2 0 gag-polypeptide of LTR copia-type Apolipoprotein PF01442.18 CBZ23161.1 - 9.1e-58 195.3 198.5 6.3e-17 62.1 35.6 14.1 2 1 7 10 10 10 5 Apolipoprotein A1/A4/E domain DUF3618 PF12277.8 CBZ23161.1 - 1.1e-15 57.5 194.5 0.049 13.9 8.6 14.8 3 1 11 14 14 14 11 Protein of unknown function (DUF3618) FYVE PF01363.21 CBZ23161.1 - 9.5e-11 41.7 9.7 2.2e-10 40.5 9.7 1.7 1 0 0 1 1 1 1 FYVE zinc finger Flg_hook PF02120.16 CBZ23161.1 - 1.2e-05 25.1 136.2 1.6 8.6 5.2 13.1 3 1 10 13 13 13 11 Flagellar hook-length control protein FliK GAS PF13851.6 CBZ23161.1 - 0.00049 19.5 163.9 0.0053 16.1 14.2 10.0 2 1 7 10 10 10 7 Growth-arrest specific micro-tubule binding IBR PF01485.21 CBZ23161.1 - 1.1 9.6 6.1 2.7 8.3 6.1 1.7 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain zf-RING_9 PF13901.6 CBZ23162.1 - 7.3e-10 39.2 0.4 0.035 14.1 0.0 3.9 4 0 0 4 4 4 3 Putative zinc-RING and/or ribbon DUF724 PF05266.14 CBZ23165.1 - 0.00041 20.2 7.2 0.00041 20.2 7.2 7.7 3 2 1 5 5 5 1 Protein of unknown function (DUF724) Surfac_D-trimer PF09006.11 CBZ23165.1 - 0.85 9.6 4.6 74 3.4 0.1 4.0 3 0 0 3 3 3 0 Lung surfactant protein D coiled-coil trimerisation DUF3906 PF13046.6 CBZ23165.1 - 8.3 6.6 8.3 13 5.9 0.2 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3906) DUF4186 PF13811.6 CBZ23166.1 - 1.2 9.2 2.6 2.8 8.0 0.1 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4186) DDRGK PF09756.9 CBZ23167.1 - 3.5e-25 88.7 24.5 4.5e-17 62.2 0.0 2.2 2 0 0 2 2 2 2 DDRGK domain MRP-S31 PF15433.6 CBZ23167.1 - 1.2 8.7 10.3 0.55 9.9 8.2 1.5 2 0 0 2 2 2 0 Mitochondrial 28S ribosomal protein S31 Pkinase PF00069.25 CBZ23168.1 - 6.5e-31 107.7 0.0 2.4e-23 82.8 0.0 3.9 4 0 0 4 4 4 3 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ23168.1 - 4e-14 52.5 0.0 1.5e-12 47.4 0.0 2.8 2 1 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 CBZ23168.1 - 0.001 18.5 0.0 0.0018 17.7 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Anophelin PF10731.9 CBZ23168.1 - 0.31 10.9 2.5 4.5 7.2 1.1 3.1 2 0 0 2 2 2 0 Thrombin inhibitor from mosquito Gpr1_Fun34_YaaH PF01184.19 CBZ23170.1 - 1e-31 110.2 17.6 1.5e-31 109.7 17.6 1.1 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family Zn_Tnp_IS91 PF14319.6 CBZ23170.1 - 0.02 14.9 0.8 0.035 14.1 0.8 1.3 1 0 0 1 1 1 0 Transposase zinc-binding domain Gpr1_Fun34_YaaH PF01184.19 CBZ23171.1 - 3.4e-50 170.5 18.0 4.4e-50 170.2 18.0 1.1 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family Gpr1_Fun34_YaaH PF01184.19 CBZ23173.1 - 4.5e-50 170.1 16.7 5.6e-50 169.8 16.7 1.1 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family MFS_1 PF07690.16 CBZ23174.1 - 4.9e-29 101.4 16.9 1.4e-18 67.0 0.1 2.2 2 0 0 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 CBZ23174.1 - 6.6e-10 37.9 0.5 1.6e-07 30.1 0.0 2.8 2 1 0 2 2 2 2 Organic Anion Transporter Polypeptide (OATP) family MFS_2 PF13347.6 CBZ23174.1 - 8.1e-08 31.2 15.8 0.00019 20.2 5.1 3.4 2 2 0 3 3 3 2 MFS/sugar transport protein ResB PF05140.14 CBZ23174.1 - 0.0077 15.0 0.0 0.012 14.3 0.0 1.3 1 0 0 1 1 1 1 ResB-like family T2SSM PF04612.12 CBZ23174.1 - 4.1 7.5 7.5 0.44 10.6 0.1 2.8 3 0 0 3 3 3 0 Type II secretion system (T2SS), protein M MHYT PF03707.16 CBZ23174.1 - 5.4 7.3 8.3 5.4 7.3 0.1 4.0 3 1 0 3 3 3 0 Bacterial signalling protein N terminal repeat Ribosomal_60s PF00428.19 CBZ23176.1 - 4.6e-21 75.2 9.9 5.2e-21 75.0 9.9 1.0 1 0 0 1 1 1 1 60s Acidic ribosomal protein PGA2 PF07543.12 CBZ23176.1 - 0.078 13.0 0.0 0.096 12.7 0.0 1.1 1 0 0 1 1 1 0 Protein trafficking PGA2 Ribosomal_60s PF00428.19 CBZ23177.1 - 6.8e-21 74.7 9.9 8.2e-21 74.4 9.9 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein PGA2 PF07543.12 CBZ23177.1 - 0.11 12.5 0.0 0.14 12.1 0.0 1.1 1 0 0 1 1 1 0 Protein trafficking PGA2 TLD PF07534.16 CBZ23178.1 - 5.1e-15 55.9 0.0 9.2e-14 51.8 0.0 2.2 2 0 0 2 2 2 1 TLD Ank_2 PF12796.7 CBZ23181.1 - 1.6e-30 105.5 0.0 6.5e-14 52.3 0.0 4.3 2 2 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 CBZ23181.1 - 1.2e-26 89.8 0.7 0.0002 21.5 0.0 7.2 7 0 0 7 7 7 4 Ankyrin repeat Ank_5 PF13857.6 CBZ23181.1 - 1.7e-25 88.7 1.8 2.6e-09 37.1 0.0 5.4 3 2 2 5 5 5 4 Ankyrin repeats (many copies) Ank_4 PF13637.6 CBZ23181.1 - 9.7e-24 83.4 3.4 1.6e-08 34.9 0.1 4.9 3 2 2 5 5 5 4 Ankyrin repeats (many copies) Ank PF00023.30 CBZ23181.1 - 2.6e-22 78.2 1.2 7.7e-06 26.1 0.1 5.9 6 0 0 6 6 6 4 Ankyrin repeat DHHC PF01529.20 CBZ23181.1 - 3.3e-08 33.7 0.9 3.1e-07 30.6 0.0 2.8 3 0 0 3 3 3 1 DHHC palmitoyltransferase PHO4 PF01384.20 CBZ23183.1 - 6.9e-92 308.1 15.4 7.9e-92 307.9 15.4 1.0 1 0 0 1 1 1 1 Phosphate transporter family SLC3A2_N PF16028.5 CBZ23183.1 - 0.65 9.6 2.5 2.1 7.9 2.5 1.8 1 0 0 1 1 1 0 Solute carrier family 3 member 2 N-terminus DSPc PF00782.20 CBZ23184.1 - 0.07 12.9 0.4 0.15 11.8 0.4 1.5 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain RRM_1 PF00076.22 CBZ23185.1 - 7.7e-12 44.9 0.6 8.2e-05 22.4 0.0 4.7 4 1 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TruD PF01142.18 CBZ23186.1 - 0.00053 18.9 0.0 0.00099 18.0 0.0 1.3 1 0 0 1 1 1 1 tRNA pseudouridine synthase D (TruD) Paramyxo_C PF01692.18 CBZ23186.1 - 0.37 10.2 1.3 0.63 9.4 0.0 2.1 2 0 0 2 2 2 0 Paramyxovirus non-structural protein C AAA PF00004.29 CBZ23187.1 - 7.4e-45 152.6 0.0 1.4e-44 151.7 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 CBZ23187.1 - 8.2e-13 47.9 1.0 1.5e-12 47.1 0.0 2.0 2 0 0 2 2 2 1 AAA+ lid domain AAA_2 PF07724.14 CBZ23187.1 - 1.1e-07 32.1 0.0 2.7e-07 30.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) Prot_ATP_ID_OB PF16450.5 CBZ23187.1 - 3.6e-07 30.0 0.2 8.5e-07 28.8 0.2 1.7 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_16 PF13191.6 CBZ23187.1 - 8.7e-07 29.5 0.0 0.0017 18.7 0.0 2.5 1 1 0 2 2 2 2 AAA ATPase domain AAA_5 PF07728.14 CBZ23187.1 - 8.9e-07 29.0 0.2 9.1e-06 25.7 0.2 2.4 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 CBZ23187.1 - 5.4e-06 26.2 0.0 1.5e-05 24.8 0.0 1.7 2 0 0 2 2 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 CBZ23187.1 - 5.2e-05 23.5 0.1 0.022 15.0 0.0 2.3 1 1 1 2 2 2 1 AAA domain DUF815 PF05673.13 CBZ23187.1 - 0.00024 20.3 0.0 0.00055 19.2 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF815) TIP49 PF06068.13 CBZ23187.1 - 0.001 18.3 0.0 0.0022 17.3 0.0 1.5 1 0 0 1 1 1 1 TIP49 P-loop domain Mg_chelatase PF01078.21 CBZ23187.1 - 0.0017 17.8 0.0 0.0033 16.8 0.0 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.22 CBZ23187.1 - 0.0018 18.6 0.0 0.0053 17.1 0.0 1.9 1 0 0 1 1 1 1 RNA helicase AAA_7 PF12775.7 CBZ23187.1 - 0.0023 17.5 0.0 0.0065 16.0 0.0 1.7 1 1 0 1 1 1 1 P-loop containing dynein motor region AAA_24 PF13479.6 CBZ23187.1 - 0.0024 17.6 0.0 0.0048 16.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 CBZ23187.1 - 0.0037 17.0 0.0 0.0084 15.9 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_14 PF13173.6 CBZ23187.1 - 0.0039 17.2 0.0 0.0085 16.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain Parvo_NS1 PF01057.17 CBZ23187.1 - 0.005 16.0 0.0 0.0087 15.2 0.0 1.3 1 0 0 1 1 1 1 Parvovirus non-structural protein NS1 AAA_18 PF13238.6 CBZ23187.1 - 0.005 17.4 0.1 0.018 15.6 0.0 2.0 2 0 0 2 2 1 1 AAA domain AAA_25 PF13481.6 CBZ23187.1 - 0.011 15.4 0.0 0.083 12.5 0.0 2.2 2 0 0 2 2 2 0 AAA domain ATPase PF06745.13 CBZ23187.1 - 0.017 14.5 2.2 0.18 11.1 0.0 2.7 2 1 1 3 3 3 0 KaiC Sigma54_activat PF00158.26 CBZ23187.1 - 0.018 14.7 0.1 0.093 12.4 0.1 2.1 1 1 0 1 1 1 0 Sigma-54 interaction domain ABC_tran PF00005.27 CBZ23187.1 - 0.019 15.5 0.1 0.14 12.7 0.0 2.3 2 0 0 2 2 2 0 ABC transporter AAA_3 PF07726.11 CBZ23187.1 - 0.023 14.5 0.0 0.051 13.5 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ATPase_2 PF01637.18 CBZ23187.1 - 0.029 14.3 0.8 0.99 9.3 0.0 2.6 2 1 1 3 3 3 0 ATPase domain predominantly from Archaea AAA_28 PF13521.6 CBZ23187.1 - 0.03 14.6 0.0 0.06 13.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain PhoH PF02562.16 CBZ23187.1 - 0.032 13.7 0.1 0.076 12.5 0.1 1.6 1 0 0 1 1 1 0 PhoH-like protein Prot_ATP_OB_N PF17758.1 CBZ23187.1 - 0.033 13.8 0.0 0.097 12.3 0.0 1.8 1 0 0 1 1 1 0 Proteasomal ATPase OB N-terminal domain TsaE PF02367.17 CBZ23187.1 - 0.042 13.8 0.0 0.087 12.8 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_33 PF13671.6 CBZ23187.1 - 0.071 13.3 0.0 0.14 12.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 CBZ23187.1 - 0.071 13.0 0.1 0.28 11.1 0.1 2.0 1 1 0 1 1 1 0 NACHT domain AAA_30 PF13604.6 CBZ23187.1 - 0.086 12.6 0.0 0.2 11.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.6 CBZ23187.1 - 0.12 12.7 0.1 0.3 11.4 0.1 1.7 1 1 0 1 1 1 0 AAA domain GpcrRhopsn4 PF10192.9 CBZ23188.1 - 0.028 13.8 2.7 0.66 9.3 1.3 2.5 2 0 0 2 2 2 0 Rhodopsin-like GPCR transmembrane domain ADH_zinc_N PF00107.26 CBZ23190.1 - 2.2e-20 73.0 0.0 4.5e-20 72.0 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 CBZ23190.1 - 4.2e-20 73.2 0.0 8.8e-20 72.1 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 CBZ23190.1 - 7.7e-09 35.4 0.1 1.5e-08 34.5 0.1 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain RNA_polI_A34 PF08208.11 CBZ23191.1 - 0.47 10.5 10.8 0.61 10.1 10.8 1.1 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 UPF0239 PF06783.11 CBZ23191.1 - 1.6 8.9 5.9 2.7 8.3 5.9 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0239) Helicase_C_2 PF13307.6 CBZ23192.1 - 1.9e-41 142.1 0.0 3.6e-41 141.2 0.0 1.5 1 0 0 1 1 1 1 Helicase C-terminal domain DEAD_2 PF06733.15 CBZ23192.1 - 6.1e-21 74.8 0.7 1.1e-07 31.7 0.0 4.4 4 0 0 4 4 4 4 DEAD_2 MRI PF15325.6 CBZ23192.1 - 0.12 13.4 3.0 1.2 10.3 0.9 3.5 2 0 0 2 2 2 0 Modulator of retrovirus infection SR-25 PF10500.9 CBZ23192.1 - 0.13 11.8 8.4 0.069 12.7 2.7 3.1 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Methyltransf_31 PF13847.6 CBZ23193.1 - 1.2e-07 31.7 0.0 1.7e-07 31.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CBZ23193.1 - 8.8e-07 29.6 0.1 2.8e-06 28.0 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 CBZ23193.1 - 0.00033 21.2 0.1 0.0014 19.2 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain PrmA PF06325.13 CBZ23193.1 - 0.0026 17.2 0.1 0.0053 16.2 0.0 1.5 2 0 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_12 PF08242.12 CBZ23193.1 - 0.0052 17.5 0.0 0.014 16.2 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.11 CBZ23193.1 - 0.0073 15.3 0.0 0.014 14.3 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) tRNA_U5-meth_tr PF05958.11 CBZ23193.1 - 0.011 14.7 0.0 0.018 14.1 0.0 1.2 1 0 0 1 1 1 0 tRNA (Uracil-5-)-methyltransferase MTS PF05175.14 CBZ23193.1 - 0.017 14.7 0.1 0.04 13.5 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase small domain MeaB PF03308.16 CBZ23194.1 - 7.8e-74 248.0 0.0 1e-73 247.6 0.0 1.1 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB cobW PF02492.19 CBZ23194.1 - 1.1e-07 31.6 0.0 3.8e-07 29.9 0.0 1.8 1 1 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain AAA_29 PF13555.6 CBZ23194.1 - 0.0011 18.6 0.0 0.0026 17.5 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.6 CBZ23194.1 - 0.0029 18.0 0.1 0.0082 16.5 0.0 1.8 2 0 0 2 2 2 1 AAA ATPase domain ParA PF10609.9 CBZ23194.1 - 0.0045 16.5 0.1 2 7.8 0.1 2.2 2 0 0 2 2 2 2 NUBPL iron-transfer P-loop NTPase AAA_22 PF13401.6 CBZ23194.1 - 0.0074 16.6 0.2 0.65 10.3 0.0 2.5 2 0 0 2 2 2 1 AAA domain GTP_EFTU PF00009.27 CBZ23194.1 - 0.0074 15.8 0.0 0.59 9.6 0.0 2.3 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain SMC_N PF02463.19 CBZ23194.1 - 0.0075 15.7 0.0 0.013 15.0 0.0 1.3 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_10 PF12846.7 CBZ23194.1 - 0.053 12.4 0.0 0.084 11.8 0.0 1.2 1 0 0 1 1 1 0 AAA-like domain CbiA PF01656.23 CBZ23194.1 - 0.093 12.8 0.0 0.11 12.5 0.0 1.3 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain KTI12 PF08433.10 CBZ23194.1 - 0.13 11.6 0.0 1.9 7.9 0.0 2.1 2 0 0 2 2 2 0 Chromatin associated protein KTI12 XRN_N PF03159.18 CBZ23195.1 - 0.13 11.6 0.0 0.22 10.9 0.0 1.3 1 0 0 1 1 1 0 XRN 5'-3' exonuclease N-terminus Med21 PF11221.8 CBZ23197.1 - 0.1 12.8 0.7 0.28 11.4 0.1 2.0 2 0 0 2 2 2 0 Subunit 21 of Mediator complex Fungus-induced PF10917.8 CBZ23198.1 - 1.5 9.2 7.0 3 8.2 0.5 3.2 3 0 0 3 3 3 0 Fungus-induced protein DUF3285 PF11688.8 CBZ23198.1 - 2.5 8.1 4.9 0.54 10.2 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3285) EIID-AGA PF03613.14 CBZ23199.1 - 0.049 12.8 0.6 0.12 11.6 0.6 1.8 1 1 0 1 1 1 0 PTS system mannose/fructose/sorbose family IID component CRT-like PF08627.10 CBZ23199.1 - 0.098 11.6 9.0 0.052 12.5 4.0 2.2 2 0 0 2 2 2 0 CRT-like, chloroquine-resistance transporter-like AAA_16 PF13191.6 CBZ23200.1 - 0.00014 22.3 0.4 0.0016 18.9 0.1 2.2 2 0 0 2 2 2 1 AAA ATPase domain AAA_14 PF13173.6 CBZ23200.1 - 0.017 15.1 0.0 0.029 14.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain RecA PF00154.21 CBZ23200.1 - 0.032 13.7 0.0 0.057 12.9 0.0 1.3 1 0 0 1 1 1 0 recA bacterial DNA recombination protein HEM4 PF02602.15 CBZ23201.1 - 9.1e-61 205.2 0.5 1e-60 205.0 0.5 1.0 1 0 0 1 1 1 1 Uroporphyrinogen-III synthase HemD DEAD PF00270.29 CBZ23202.1 - 2.3e-19 69.8 0.0 4.6e-18 65.6 0.0 2.9 3 0 0 3 3 3 1 DEAD/DEAH box helicase ResIII PF04851.15 CBZ23202.1 - 5.6e-09 36.2 0.0 1.5e-08 34.8 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 CBZ23202.1 - 0.00017 21.9 0.1 0.00049 20.4 0.1 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Nop53 PF07767.11 CBZ23202.1 - 3.4 6.9 18.3 0.083 12.3 7.4 2.5 2 0 0 2 2 2 0 Nop53 (60S ribosomal biogenesis) Beta_helix PF13229.6 CBZ23203.1 - 0.0012 18.7 1.0 64 3.4 0.0 6.0 7 1 0 7 7 7 2 Right handed beta helix region tRNA_edit PF04073.15 CBZ23204.1 - 8.9e-19 67.8 0.1 3.4e-18 65.9 0.1 1.8 1 1 0 1 1 1 1 Aminoacyl-tRNA editing domain Mqo PF06039.15 CBZ23206.1 - 0.043 12.4 0.0 0.068 11.7 0.0 1.2 1 0 0 1 1 1 0 Malate:quinone oxidoreductase (Mqo) COX17 PF05051.13 CBZ23207.1 - 4e-15 55.9 8.0 5.2e-15 55.5 8.0 1.1 1 0 0 1 1 1 1 Cytochrome C oxidase copper chaperone (COX17) Rbsn PF11464.8 CBZ23207.1 - 0.028 14.1 0.3 8.1 6.3 0.0 2.2 2 0 0 2 2 2 0 Rabenosyn Rab binding domain TatD_DNase PF01026.21 CBZ23208.1 - 8.1e-57 192.5 0.0 1.3e-56 191.9 0.0 1.3 1 0 0 1 1 1 1 TatD related DNase DUF4551 PF15087.6 CBZ23208.1 - 0.0089 14.9 6.0 0.017 14.0 6.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4551) Amidohydro_2 PF04909.14 CBZ23208.1 - 0.049 13.4 0.1 0.1 12.4 0.1 1.5 1 0 0 1 1 1 0 Amidohydrolase LRR_4 PF12799.7 CBZ23210.1 - 1.7e-13 50.5 3.5 0.00016 22.0 0.0 3.7 3 0 0 3 3 3 3 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 CBZ23210.1 - 7.9e-10 38.5 1.6 0.0024 17.4 0.4 3.6 3 1 1 4 4 4 3 Leucine-rich repeat Ubiquitin_2 PF14560.6 CBZ23210.1 - 3.8e-09 36.9 0.0 7.3e-09 36.0 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-like domain LRR_8 PF13855.6 CBZ23210.1 - 5.6e-08 32.4 6.9 0.0054 16.5 1.4 4.0 3 1 0 3 3 3 3 Leucine rich repeat ubiquitin PF00240.23 CBZ23210.1 - 8.3e-06 25.5 0.2 0.00014 21.6 0.2 2.4 1 1 0 1 1 1 1 Ubiquitin family LRR_6 PF13516.6 CBZ23210.1 - 0.056 13.5 11.9 2.1 8.6 0.0 5.1 5 0 0 5 5 5 0 Leucine Rich repeat LRR_1 PF00560.33 CBZ23210.1 - 0.97 10.2 3.3 1.2e+02 3.9 0.0 4.2 4 0 0 4 4 4 0 Leucine Rich Repeat Pkinase PF00069.25 CBZ23211.1 - 1.1e-52 179.1 0.1 1.6e-29 103.1 0.0 3.2 3 0 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ23211.1 - 5.9e-23 81.5 0.0 4.7e-08 32.6 0.0 3.2 3 0 0 3 3 3 3 Protein tyrosine kinase Pkinase_fungal PF17667.1 CBZ23211.1 - 0.0028 16.5 0.0 0.0067 15.3 0.0 1.6 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 CBZ23211.1 - 0.049 12.9 0.0 0.1 11.9 0.0 1.4 1 0 0 1 1 1 0 Kinase-like RNA_pol_Rpb4 PF03874.16 CBZ23212.1 - 0.036 14.4 0.0 0.35 11.2 0.0 2.2 2 0 0 2 2 2 0 RNA polymerase Rpb4 KAR9 PF08580.10 CBZ23212.1 - 4.4 5.7 6.4 3.7 6.0 1.0 2.0 2 0 0 2 2 2 0 Yeast cortical protein KAR9 6PF2K PF01591.18 CBZ23213.1 - 1.2e-64 217.7 0.0 1.8e-64 217.1 0.0 1.2 1 0 0 1 1 1 1 6-phosphofructo-2-kinase Ank_2 PF12796.7 CBZ23213.1 - 7.8e-13 48.8 0.1 1.9e-12 47.6 0.1 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CBZ23213.1 - 9e-12 45.3 0.8 8e-09 35.9 0.0 2.7 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 CBZ23213.1 - 1e-11 44.9 1.4 7.6e-11 42.0 0.2 2.0 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 CBZ23213.1 - 1e-08 35.2 1.2 3.8e-06 27.1 0.0 3.3 3 0 0 3 3 3 1 Ankyrin repeat Ank_3 PF13606.6 CBZ23213.1 - 8.3e-07 28.9 0.1 0.0076 16.7 0.0 2.9 2 0 0 2 2 2 2 Ankyrin repeat AAA_33 PF13671.6 CBZ23213.1 - 1.1e-05 25.6 0.3 3.2e-05 24.1 0.0 2.0 2 0 0 2 2 2 1 AAA domain His_Phos_1 PF00300.22 CBZ23213.1 - 0.00012 21.8 0.1 0.093 12.4 0.0 2.9 3 0 0 3 3 3 2 Histidine phosphatase superfamily (branch 1) Phage_base_V PF04717.12 CBZ23214.1 - 0.075 13.0 0.0 0.21 11.5 0.0 1.7 1 0 0 1 1 1 0 Type VI secretion system, phage-baseplate injector ANAPC5 PF12862.7 CBZ23215.1 - 0.34 11.0 4.8 1.6 8.9 4.8 2.2 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 5 CDP-OH_P_transf PF01066.21 CBZ23216.1 - 4.3e-16 59.4 0.6 1.4e-15 57.8 0.1 2.2 2 0 0 2 2 2 1 CDP-alcohol phosphatidyltransferase zf-C6H2 PF15801.5 CBZ23218.1 - 7.9e-09 35.7 7.7 1.8e-08 34.6 7.7 1.6 1 0 0 1 1 1 1 zf-MYND-like zinc finger, mRNA-binding zf-MYND PF01753.18 CBZ23218.1 - 0.027 14.6 6.4 0.057 13.5 6.4 1.6 1 0 0 1 1 1 0 MYND finger LRR_4 PF12799.7 CBZ23221.1 - 4.4e-08 33.3 13.0 0.027 14.9 0.7 5.0 2 1 3 6 6 6 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CBZ23221.1 - 8.2e-08 31.9 17.6 7e-05 22.5 1.1 3.5 3 1 0 3 3 3 2 Leucine rich repeat LRR_6 PF13516.6 CBZ23221.1 - 0.069 13.2 11.6 36 4.8 0.1 5.6 6 0 0 6 6 6 0 Leucine Rich repeat NIF PF03031.18 CBZ23223.1 - 4.3e-27 94.8 0.1 4.3e-19 68.8 0.0 2.7 3 0 0 3 3 3 2 NLI interacting factor-like phosphatase Brix PF04427.18 CBZ23224.1 - 7.4e-34 117.5 0.1 1.1e-33 116.9 0.1 1.3 1 0 0 1 1 1 1 Brix domain Pyrophosphatase PF00719.19 CBZ23225.1 - 4.4e-43 146.8 0.0 5.8e-43 146.5 0.0 1.1 1 0 0 1 1 1 1 Inorganic pyrophosphatase Got1 PF04178.12 CBZ23226.1 - 1.9e-29 102.3 20.6 2.8e-29 101.8 20.6 1.3 1 0 0 1 1 1 1 Got1/Sft2-like family DUF202 PF02656.15 CBZ23226.1 - 0.51 10.8 3.2 3.3 8.2 0.0 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF202) IBV_3C PF03620.13 CBZ23226.1 - 3.1 8.3 8.0 0.95 10.0 4.9 1.8 1 1 1 2 2 2 0 IBV 3C protein ECF_trnsprt PF12822.7 CBZ23226.1 - 5.7 7.0 16.4 0.45 10.6 4.4 2.3 1 1 1 2 2 2 0 ECF transporter, substrate-specific component SdpI PF13630.6 CBZ23226.1 - 7.2 6.8 16.2 2.7 8.2 2.4 2.7 3 0 0 3 3 3 0 SdpI/YhfL protein family Amidohydro_3 PF07969.11 CBZ23227.1 - 8.8e-61 206.8 8.4 1.5e-60 206.1 8.4 1.4 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_1 PF01979.20 CBZ23227.1 - 4.8e-14 52.4 1.9 9.1e-09 35.1 0.2 3.2 3 0 0 3 3 3 3 Amidohydrolase family Cu-oxidase_2 PF07731.14 CBZ23229.1 - 6.3e-20 71.3 7.3 3e-19 69.1 1.6 3.4 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase_3 PF07732.15 CBZ23229.1 - 2.4e-09 37.2 5.7 3.1e-06 27.2 0.6 3.9 3 1 1 4 4 4 2 Multicopper oxidase FPN1 PF06963.12 CBZ23230.1 - 0.13 10.8 0.0 0.15 10.6 0.0 1.0 1 0 0 1 1 1 0 Ferroportin1 (FPN1) MORN PF02493.20 CBZ23231.1 - 1.5e-23 81.2 36.9 1.9e-06 27.4 1.3 7.3 7 1 0 7 7 7 6 MORN repeat Tudor_2 PF18104.1 CBZ23231.1 - 0.041 13.6 0.5 5.9 6.7 0.1 3.0 2 0 0 2 2 2 0 Jumonji domain-containing protein 2A Tudor domain EIF_2_alpha PF07541.12 CBZ23232.1 - 1.3e-16 60.7 0.0 9.5e-15 54.7 0.0 2.2 1 1 1 2 2 2 2 Eukaryotic translation initiation factor 2 alpha subunit S1 PF00575.23 CBZ23232.1 - 2.4e-12 47.0 0.6 5.4e-12 45.9 0.6 1.6 1 0 0 1 1 1 1 S1 RNA binding domain EXOSC1 PF10447.9 CBZ23232.1 - 0.03 14.9 0.1 0.06 14.0 0.1 1.6 1 1 0 1 1 1 0 Exosome component EXOSC1/CSL4 E1-E2_ATPase PF00122.20 CBZ23233.1 - 1.3e-47 161.6 1.1 1.3e-47 161.6 1.1 2.3 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 CBZ23233.1 - 9.6e-44 149.3 5.9 9.6e-44 149.3 5.9 2.1 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 CBZ23233.1 - 1.6e-21 77.6 0.1 1.8e-20 74.2 0.1 2.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 CBZ23233.1 - 3.8e-17 62.2 0.0 9.9e-17 60.8 0.0 1.8 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 CBZ23233.1 - 5.6e-14 51.6 0.0 1.7e-13 50.0 0.0 1.8 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 CBZ23233.1 - 6.5e-07 29.3 2.6 8.3e-06 25.7 0.6 2.5 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 CBZ23233.1 - 0.0016 18.9 0.0 0.004 17.6 0.0 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Abhydrolase_9_N PF15420.6 CBZ23233.1 - 0.46 10.4 6.3 0.81 9.6 0.3 2.5 2 0 0 2 2 2 0 Alpha/beta-hydrolase family N-terminus BT1 PF03092.16 CBZ23234.1 - 1.8e-186 620.5 13.9 2.2e-186 620.2 13.9 1.0 1 0 0 1 1 1 1 BT1 family PDEase_I PF00233.19 CBZ23235.1 - 4e-20 72.6 0.0 6e-20 72.0 0.0 1.2 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase DUF4942 PF13708.6 CBZ23235.1 - 0.2 11.6 0.2 0.34 10.9 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4942) Topo_C_assoc PF14370.6 CBZ23240.1 - 3.9e-28 97.2 0.3 5.5e-28 96.7 0.3 1.2 1 0 0 1 1 1 1 C-terminal topoisomerase domain DUF4171 PF13775.6 CBZ23240.1 - 0.0042 17.5 8.1 0.0076 16.7 8.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4171) DUF4614 PF15391.6 CBZ23240.1 - 0.035 14.1 6.5 0.058 13.4 6.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) SPX PF03105.19 CBZ23240.1 - 0.038 13.9 3.7 0.039 13.9 3.7 1.1 1 0 0 1 1 1 0 SPX domain Miga PF10265.9 CBZ23240.1 - 0.068 12.1 1.2 0.073 12.0 1.2 1.1 1 0 0 1 1 1 0 Mitoguardin Macoilin PF09726.9 CBZ23240.1 - 0.074 11.6 3.0 0.081 11.5 3.0 1.1 1 0 0 1 1 1 0 Macoilin family RAP1 PF07218.11 CBZ23240.1 - 0.17 10.1 12.9 0.22 9.7 12.9 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Secretin_N_2 PF07655.13 CBZ23240.1 - 9.1 6.9 17.2 19 5.8 17.2 1.5 1 0 0 1 1 1 0 Secretin N-terminal domain Methyltransf_25 PF13649.6 CBZ23241.1 - 0.00024 21.7 0.1 0.00065 20.4 0.1 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CBZ23241.1 - 0.0023 17.7 0.0 0.0034 17.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain APG17 PF04108.12 CBZ23242.1 - 0.003 16.8 0.3 0.0033 16.6 0.3 1.0 1 0 0 1 1 1 1 Autophagy protein Apg17 Takusan PF04822.13 CBZ23242.1 - 0.045 13.6 3.1 0.085 12.7 3.1 1.5 1 0 0 1 1 1 0 Takusan CorA PF01544.18 CBZ23242.1 - 0.05 12.9 0.2 0.059 12.7 0.2 1.1 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein DASH_Dam1 PF08653.10 CBZ23242.1 - 0.12 12.2 0.1 0.18 11.6 0.1 1.2 1 0 0 1 1 1 0 DASH complex subunit Dam1 WXG100 PF06013.12 CBZ23242.1 - 0.13 12.5 0.3 0.13 12.5 0.3 1.7 2 0 0 2 2 2 0 Proteins of 100 residues with WXG FlaC_arch PF05377.11 CBZ23242.1 - 0.16 12.4 0.4 0.28 11.6 0.4 1.4 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) DUF3584 PF12128.8 CBZ23244.1 - 0.0028 15.3 5.8 0.0039 14.8 5.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) eIF3_N PF09440.10 CBZ23244.1 - 0.059 13.8 4.8 0.37 11.2 0.2 2.3 1 1 1 2 2 2 0 eIF3 subunit 6 N terminal domain HOOK PF05622.12 CBZ23245.1 - 0.021 13.0 3.4 0.023 12.9 2.3 1.6 2 0 0 2 2 2 0 HOOK protein Rootletin PF15035.6 CBZ23245.1 - 0.035 14.1 4.3 1.4 8.9 2.8 2.3 2 0 0 2 2 2 0 Ciliary rootlet component, centrosome cohesion CENP-H PF05837.12 CBZ23245.1 - 0.68 10.4 6.4 0.73 10.3 3.5 2.4 2 0 0 2 2 2 0 Centromere protein H (CENP-H) KH_6 PF15985.5 CBZ23246.1 - 2.8e-09 37.2 0.0 9.8e-09 35.4 0.0 1.9 1 1 0 1 1 1 1 KH domain Av_adeno_fibre PF06536.11 CBZ23248.1 - 0.11 12.3 0.0 0.24 11.3 0.0 1.5 1 0 0 1 1 1 0 Avian adenovirus fibre, N-terminal VSP PF03302.13 CBZ23250.1 - 1.3e-06 27.5 151.0 0.0008 18.4 11.4 7.6 1 1 6 8 8 8 6 Giardia variant-specific surface protein VSP PF03302.13 CBZ23251.1 - 0.00017 20.6 121.8 0.0035 16.3 13.2 7.5 2 1 6 8 8 8 6 Giardia variant-specific surface protein cEGF PF12662.7 CBZ23252.1 - 0.11 12.4 6.3 4.4 7.3 0.6 2.8 2 0 0 2 2 2 0 Complement Clr-like EGF-like FSA_C PF10479.9 CBZ23252.1 - 9.5 4.2 9.3 11 4.1 9.3 1.1 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus VSP PF03302.13 CBZ23253.1 - 0.028 13.3 41.5 0.023 13.5 6.0 3.9 1 1 2 4 4 4 0 Giardia variant-specific surface protein DUF5075 PF16825.5 CBZ23254.1 - 0.0004 20.1 0.8 0.45 10.2 0.4 2.3 2 0 0 2 2 2 2 IGP family C-type lectin domain NINJA_B PF16136.5 CBZ23254.1 - 0.093 13.1 0.2 0.2 12.1 0.2 1.5 1 0 0 1 1 1 0 Putative nuclear localisation signal Orthoreo_P10 PF07204.11 CBZ23255.1 - 0.028 14.4 0.1 0.046 13.7 0.1 1.4 1 0 0 1 1 1 0 Orthoreovirus membrane fusion protein p10 RP-C_C PF11800.8 CBZ23255.1 - 0.12 12.4 0.0 0.18 11.9 0.0 1.1 1 0 0 1 1 1 0 Replication protein C C-terminal region Sporozoite_P67 PF05642.11 CBZ23255.1 - 1.2 7.2 3.9 1.9 6.5 3.9 1.3 1 0 0 1 1 1 0 Sporozoite P67 surface antigen GRAM PF02893.20 CBZ23256.1 - 4.2e-06 26.6 0.1 1.2e-05 25.2 0.0 1.9 2 1 0 2 2 2 1 GRAM domain PseudoU_synth_2 PF00849.22 CBZ23257.1 - 1e-40 139.4 0.0 1.8e-40 138.7 0.0 1.4 1 0 0 1 1 1 1 RNA pseudouridylate synthase TPR_1 PF00515.28 CBZ23258.1 - 0.00039 20.1 10.4 0.0025 17.5 0.0 3.4 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 CBZ23258.1 - 0.00075 19.4 14.2 0.0035 17.4 0.0 4.4 4 1 0 4 4 4 1 Tetratricopeptide repeat TPR_10 PF13374.6 CBZ23258.1 - 0.0051 16.6 0.1 0.0051 16.6 0.1 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.6 CBZ23258.1 - 0.01 15.8 1.5 0.21 11.7 0.0 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 CBZ23258.1 - 0.011 15.8 0.1 0.029 14.4 0.1 1.7 1 0 0 1 1 1 0 Fis1 C-terminal tetratricopeptide repeat TPR_12 PF13424.6 CBZ23258.1 - 0.014 15.7 0.2 0.014 15.7 0.2 3.5 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.6 CBZ23258.1 - 0.041 14.1 2.5 0.077 13.3 0.0 2.7 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_16 PF13432.6 CBZ23258.1 - 3.8 8.2 25.3 0.5 11.0 0.6 4.5 3 1 1 4 4 4 0 Tetratricopeptide repeat MRP-L47 PF06984.13 CBZ23259.1 - 5e-29 100.3 0.2 9.4e-29 99.4 0.2 1.5 1 0 0 1 1 1 1 Mitochondrial 39-S ribosomal protein L47 (MRP-L47) TarH PF02203.15 CBZ23259.1 - 0.2 11.6 0.6 14 5.6 0.1 2.2 2 0 0 2 2 2 0 Tar ligand binding domain homologue A_deaminase PF00962.22 CBZ23260.1 - 2.3e-91 306.6 0.6 4.9e-66 223.3 0.0 3.3 4 0 0 4 4 4 2 Adenosine/AMP deaminase SLD3 PF08639.10 CBZ23260.1 - 0.002 17.0 0.8 0.0036 16.1 0.8 1.3 1 0 0 1 1 1 1 DNA replication regulator SLD3 T2SSM_b PF10741.9 CBZ23260.1 - 0.44 10.4 3.7 0.67 9.8 0.0 2.9 3 0 0 3 3 3 0 Type II secretion system (T2SS), protein M subtype b ADH_N PF08240.12 CBZ23261.1 - 9.4e-06 25.5 0.7 1.9e-05 24.5 0.7 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain DUF2459 PF09601.10 CBZ23261.1 - 0.072 12.9 0.0 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2459) DUF4164 PF13747.6 CBZ23262.1 - 0.002 18.4 0.1 0.0044 17.3 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4164) TRCF PF03461.15 CBZ23262.1 - 0.049 14.0 0.0 0.089 13.2 0.0 1.4 1 0 0 1 1 1 0 TRCF domain Glyco_hydro_32N PF00251.20 CBZ23263.1 - 5.7e-57 193.6 7.7 7.6e-57 193.2 7.7 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 N-terminal domain Glyco_hydro_32C PF08244.12 CBZ23263.1 - 2e-12 47.4 0.0 5.4e-12 46.0 0.0 1.7 1 1 0 1 1 1 1 Glycosyl hydrolases family 32 C terminal PAN_1 PF00024.26 CBZ23263.1 - 0.00016 21.5 0.3 0.00034 20.5 0.3 1.5 1 0 0 1 1 1 1 PAN domain PAN_4 PF14295.6 CBZ23263.1 - 0.013 15.4 1.7 0.043 13.7 1.7 1.8 1 0 0 1 1 1 0 PAN domain DUF5074 PF16819.5 CBZ23263.1 - 0.017 15.2 0.3 8.4 6.5 0.0 2.9 2 1 0 2 2 2 0 Domain of unknown function (DUF5074) RET_CLD3 PF17812.1 CBZ23263.1 - 0.086 13.1 0.2 0.65 10.3 0.2 2.3 2 0 0 2 2 2 0 RET Cadherin like domain 3 Glyco_hydro_32N PF00251.20 CBZ23264.1 - 8.9e-17 61.6 0.1 1.3e-16 61.0 0.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 N-terminal domain Glyco_hydro_32C PF08244.12 CBZ23264.1 - 3e-13 50.0 0.0 8.4e-13 48.6 0.0 1.7 1 1 0 1 1 1 1 Glycosyl hydrolases family 32 C terminal PAN_1 PF00024.26 CBZ23264.1 - 8.6e-05 22.4 0.3 0.00018 21.4 0.3 1.5 1 0 0 1 1 1 1 PAN domain PAN_4 PF14295.6 CBZ23264.1 - 0.0073 16.2 1.7 0.024 14.5 1.7 1.8 1 0 0 1 1 1 1 PAN domain RET_CLD3 PF17812.1 CBZ23264.1 - 0.029 14.6 0.1 0.35 11.1 0.2 2.3 2 0 0 2 2 2 0 RET Cadherin like domain 3 RNB PF00773.19 CBZ23265.1 - 8.4e-54 183.1 0.0 3.8e-53 180.9 0.0 1.9 2 0 0 2 2 2 1 RNB domain Arf PF00025.21 CBZ23266.1 - 6.6e-54 182.0 0.0 7.8e-54 181.8 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.22 CBZ23266.1 - 5.7e-15 55.3 0.0 6.5e-15 55.1 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CBZ23266.1 - 3.8e-14 52.9 0.0 4.9e-14 52.6 0.0 1.1 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 CBZ23266.1 - 1.5e-10 40.8 0.0 1.9e-10 40.5 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 CBZ23266.1 - 1.3e-08 34.5 0.0 1.7e-08 34.1 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region G-alpha PF00503.20 CBZ23266.1 - 1.6e-08 34.1 0.2 2e-05 24.0 0.0 2.3 1 1 1 2 2 2 2 G-protein alpha subunit MMR_HSR1 PF01926.23 CBZ23266.1 - 2.7e-07 30.7 0.0 3.6e-07 30.3 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase NACHT PF05729.12 CBZ23266.1 - 0.073 13.0 0.1 0.096 12.6 0.1 1.4 1 1 0 1 1 1 0 NACHT domain AAA_21 PF13304.6 CBZ23266.1 - 0.08 12.7 0.3 0.23 11.2 0.1 1.7 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 CBZ23266.1 - 0.2 11.3 0.4 0.35 10.5 0.4 1.3 1 0 0 1 1 1 0 AAA ATPase domain zf-MYND PF01753.18 CBZ23267.1 - 0.0065 16.5 9.4 0.016 15.3 9.4 1.7 1 0 0 1 1 1 1 MYND finger DUF3439 PF11921.8 CBZ23267.1 - 0.71 9.8 4.7 0.31 11.0 1.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) zf-FCS PF06467.14 CBZ23267.1 - 4.3 7.4 7.0 8.9 6.4 7.0 1.6 1 0 0 1 1 1 0 MYM-type Zinc finger with FCS sequence motif LTXXQ PF07813.12 CBZ23268.1 - 0.12 13.1 5.7 0.12 13.1 4.2 1.7 2 0 0 2 2 2 0 LTXXQ motif family protein PhyH PF05721.13 CBZ23269.1 - 7.9e-43 147.2 0.0 1e-42 146.8 0.0 1.1 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) DUF3243 PF11588.8 CBZ23269.1 - 0.17 12.2 0.0 0.42 11.0 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3243) Shisa PF13908.6 CBZ23270.1 - 6.7e-05 23.2 0.3 0.00014 22.1 0.0 1.7 2 0 0 2 2 2 1 Wnt and FGF inhibitory regulator FixS PF03597.15 CBZ23270.1 - 0.0016 18.1 0.0 0.0031 17.2 0.0 1.5 1 0 0 1 1 1 1 Cytochrome oxidase maturation protein cbb3-type EphA2_TM PF14575.6 CBZ23270.1 - 0.019 15.9 0.0 0.045 14.6 0.0 1.6 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Epiglycanin_C PF14654.6 CBZ23270.1 - 0.019 15.0 0.0 0.039 14.0 0.0 1.5 1 0 0 1 1 1 0 Mucin, catalytic, TM and cytoplasmic tail region m04gp34like PF12216.8 CBZ23270.1 - 0.03 13.9 0.0 0.051 13.1 0.0 1.3 1 0 0 1 1 1 0 Immune evasion protein FAM163 PF15069.6 CBZ23270.1 - 0.045 14.2 0.1 0.1 13.0 0.1 1.6 1 0 0 1 1 1 0 FAM163 family Arch_flagellin PF01917.16 CBZ23270.1 - 10 6.3 7.4 27 4.9 3.1 2.2 2 0 0 2 2 2 0 Archaebacterial flagellin ANAPC10 PF03256.16 CBZ23271.1 - 1.4e-60 204.2 0.0 1e-54 185.0 0.0 2.1 2 0 0 2 2 2 2 Anaphase-promoting complex, subunit 10 (APC10) TPR_1 PF00515.28 CBZ23273.1 - 2e-09 36.9 1.1 0.00098 18.9 0.0 3.0 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.17 CBZ23273.1 - 1.1e-06 28.3 13.0 9.3e-05 22.3 0.2 3.9 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 CBZ23273.1 - 1.8e-05 24.6 0.5 0.048 13.9 0.0 3.2 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.6 CBZ23273.1 - 1.8e-05 25.1 18.2 0.0083 16.9 0.0 5.6 5 2 1 6 6 6 2 Tetratricopeptide repeat TPR_11 PF13414.6 CBZ23273.1 - 2.9e-05 23.7 7.4 0.0044 16.7 0.5 2.6 2 0 0 2 2 2 2 TPR repeat SNAP PF14938.6 CBZ23273.1 - 0.0017 17.8 0.3 0.038 13.4 0.1 2.3 2 0 0 2 2 2 1 Soluble NSF attachment protein, SNAP TPR_6 PF13174.6 CBZ23273.1 - 0.012 16.3 0.1 1.2 9.9 0.0 3.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.6 CBZ23273.1 - 0.033 14.2 1.2 3.2 8.0 0.1 3.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_15 PF13429.6 CBZ23273.1 - 0.049 12.8 5.7 0.55 9.4 0.1 2.9 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_21 PF09976.9 CBZ23273.1 - 0.071 12.8 0.3 0.071 12.8 0.3 3.4 2 1 1 4 4 4 0 Tetratricopeptide repeat-like domain TPR_9 PF13371.6 CBZ23273.1 - 0.083 13.0 7.2 0.29 11.3 0.4 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat Spore_SspJ PF09575.10 CBZ23273.1 - 0.094 13.1 1.0 0.34 11.3 1.0 1.9 1 0 0 1 1 1 0 Small spore protein J (Spore_SspJ) COMMD1_N PF17221.3 CBZ23273.1 - 0.2 11.9 1.6 5.4 7.4 0.0 2.8 3 0 0 3 3 2 0 COMMD1 N-terminal domain TPR_12 PF13424.6 CBZ23273.1 - 0.22 11.8 12.0 0.72 10.2 0.2 4.4 4 1 0 5 5 5 0 Tetratricopeptide repeat TPR_19 PF14559.6 CBZ23273.1 - 0.75 10.3 17.8 0.51 10.9 0.5 4.4 4 1 0 4 4 4 0 Tetratricopeptide repeat TPR_16 PF13432.6 CBZ23273.1 - 3.3 8.4 21.3 2 9.1 0.3 4.9 4 1 0 4 4 4 0 Tetratricopeptide repeat Alkyl_sulf_dimr PF14863.6 CBZ23273.1 - 4.1 7.9 7.0 5.4 7.5 0.2 3.1 3 0 0 3 3 3 0 Alkyl sulfatase dimerisation Lectin_C PF00059.21 CBZ23274.1 - 0.18 12.6 0.0 0.84 10.4 0.0 2.2 2 0 0 2 2 2 0 Lectin C-type domain Pkinase PF00069.25 CBZ23275.1 - 8.2e-41 140.1 0.0 2.1e-21 76.5 0.0 4.5 4 1 0 4 4 4 4 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ23275.1 - 2e-32 112.5 0.0 4.6e-16 58.9 0.0 4.2 4 0 0 4 4 4 4 Protein tyrosine kinase Pkinase_fungal PF17667.1 CBZ23275.1 - 7.4e-05 21.7 1.1 0.00018 20.5 1.1 1.7 1 1 0 1 1 1 1 Fungal protein kinase APH PF01636.23 CBZ23275.1 - 0.046 13.6 2.9 2 8.3 0.0 2.5 2 0 0 2 2 2 0 Phosphotransferase enzyme family DUF4800 PF16057.5 CBZ23275.1 - 0.15 11.3 3.1 0.26 10.5 3.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4800) Peptidase_C2 PF00648.21 CBZ23276.1 - 1e-55 188.9 0.0 1.6e-55 188.3 0.0 1.2 1 0 0 1 1 1 1 Calpain family cysteine protease DUF1935 PF09149.10 CBZ23276.1 - 2.9e-33 114.3 0.1 6.4e-33 113.2 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1935) Lyase_1 PF00206.20 CBZ23277.1 - 7.1e-49 166.9 0.0 1e-48 166.3 0.0 1.2 1 0 0 1 1 1 1 Lyase ASL_C PF08328.11 CBZ23277.1 - 2.1e-44 150.3 0.0 3.7e-44 149.5 0.0 1.4 1 0 0 1 1 1 1 Adenylosuccinate lyase C-terminal Thoc2 PF11732.8 CBZ23277.1 - 0.081 13.0 0.0 0.17 11.9 0.0 1.5 1 0 0 1 1 1 0 Transcription- and export-related complex subunit N_Asn_amidohyd PF14736.6 CBZ23278.1 - 1.9e-05 24.0 0.1 0.084 12.0 0.0 3.4 3 1 0 3 3 3 2 Protein N-terminal asparagine amidohydrolase Ribosomal_L5_C PF00673.21 CBZ23279.1 - 8.2e-21 74.0 0.0 1.3e-20 73.3 0.0 1.3 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.19 CBZ23279.1 - 4.4e-18 65.4 0.2 1.1e-16 60.8 0.0 2.2 2 0 0 2 2 2 1 Ribosomal protein L5 Arf PF00025.21 CBZ23280.1 - 6.2e-58 195.1 0.0 6.9e-58 194.9 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 CBZ23280.1 - 7.4e-14 52.0 0.0 9.6e-14 51.6 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 CBZ23280.1 - 8e-13 48.2 0.0 9.3e-13 48.0 0.0 1.0 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.22 CBZ23280.1 - 1.3e-10 41.1 0.0 1.6e-10 40.8 0.0 1.1 1 0 0 1 1 1 1 Ras family G-alpha PF00503.20 CBZ23280.1 - 2.3e-09 36.9 0.0 3e-08 33.2 0.0 2.1 1 1 1 2 2 2 1 G-protein alpha subunit Gtr1_RagA PF04670.12 CBZ23280.1 - 4.9e-06 26.1 0.0 6.1e-06 25.8 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 CBZ23280.1 - 0.00039 20.5 0.0 0.00052 20.1 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase NACHT PF05729.12 CBZ23280.1 - 0.0049 16.8 0.2 0.059 13.3 0.2 2.0 1 1 0 1 1 1 1 NACHT domain ATP_bind_1 PF03029.17 CBZ23280.1 - 0.015 15.1 0.0 0.067 13.0 0.0 1.8 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein GTP_EFTU PF00009.27 CBZ23280.1 - 0.046 13.2 0.0 0.22 11.0 0.0 1.8 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain TPM_phosphatase PF04536.14 CBZ23280.1 - 0.16 12.2 0.0 0.31 11.2 0.0 1.5 1 1 0 1 1 1 0 TPM domain Rbx_binding PF18113.1 CBZ23281.1 - 0.049 13.4 0.0 0.11 12.3 0.0 1.6 1 0 0 1 1 1 0 Rubredoxin binding C-terminal domain NTP_transf_2 PF01909.23 CBZ23282.1 - 1.5e-06 28.4 0.0 3.2e-06 27.3 0.0 1.6 1 0 0 1 1 1 1 Nucleotidyltransferase domain PAP_assoc PF03828.19 CBZ23282.1 - 0.00047 20.3 0.1 0.00099 19.3 0.1 1.5 1 0 0 1 1 1 1 Cid1 family poly A polymerase DUF2852 PF11014.8 CBZ23282.1 - 0.046 13.9 0.5 0.25 11.5 0.4 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2852) Polbeta PF18765.1 CBZ23282.1 - 0.11 12.6 0.0 0.22 11.6 0.0 1.4 1 0 0 1 1 1 0 Polymerase beta, Nucleotidyltransferase Ank_4 PF13637.6 CBZ23284.1 - 5.5e-20 71.5 1.9 6.8e-08 32.9 0.0 6.1 4 2 2 6 6 6 5 Ankyrin repeats (many copies) Ank_2 PF12796.7 CBZ23284.1 - 2.4e-19 69.7 2.2 1.3e-09 38.5 0.0 4.6 3 1 1 4 4 4 3 Ankyrin repeats (3 copies) Ank PF00023.30 CBZ23284.1 - 3.5e-17 62.0 10.8 7.7e-08 32.4 0.0 6.6 6 1 0 6 6 6 3 Ankyrin repeat Ank_3 PF13606.6 CBZ23284.1 - 1.1e-15 56.1 4.3 1.8e-05 24.7 0.0 6.8 7 0 0 7 7 7 3 Ankyrin repeat Ank_5 PF13857.6 CBZ23284.1 - 1.2e-15 57.4 6.0 6e-11 42.4 0.1 4.1 4 0 0 4 4 4 2 Ankyrin repeats (many copies) DHHC PF01529.20 CBZ23284.1 - 1.8e-14 54.0 1.7 1.8e-14 54.0 1.7 2.3 2 1 0 2 2 2 1 DHHC palmitoyltransferase FixQ PF05545.11 CBZ23284.1 - 0.99 9.4 4.1 12 6.0 1.0 2.7 2 0 0 2 2 2 0 Cbb3-type cytochrome oxidase component FixQ HAUS5 PF14817.6 CBZ23285.1 - 0.00025 19.9 0.1 0.00041 19.2 0.1 1.2 1 0 0 1 1 1 1 HAUS augmin-like complex subunit 5 OmpH PF03938.14 CBZ23285.1 - 0.19 12.1 0.1 0.19 12.1 0.1 2.0 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) TFIIA PF03153.13 CBZ23285.1 - 0.8 9.6 5.8 0.99 9.3 5.8 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit EF-hand_6 PF13405.6 CBZ23286.1 - 3.3e-08 32.8 0.3 0.47 10.5 0.0 4.2 4 0 0 4 4 4 2 EF-hand domain EF-hand_7 PF13499.6 CBZ23286.1 - 9.8e-08 32.4 0.0 0.0081 16.6 0.2 2.5 2 0 0 2 2 2 2 EF-hand domain pair zf-RING_UBOX PF13445.6 CBZ23286.1 - 1.7e-05 24.7 2.8 1.7e-05 24.7 2.8 3.4 3 1 0 3 3 3 1 RING-type zinc-finger zf-C3HC4 PF00097.25 CBZ23286.1 - 2.4e-05 24.1 6.2 9e-05 22.3 6.2 2.1 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 CBZ23286.1 - 6.3e-05 22.7 8.4 0.0011 18.7 8.6 2.7 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 CBZ23286.1 - 9.3e-05 22.5 7.8 9.3e-05 22.5 7.8 2.7 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING EF-hand_1 PF00036.32 CBZ23286.1 - 0.0002 20.6 0.1 0.87 9.3 0.0 3.8 4 0 0 4 4 4 1 EF hand zf-RING_5 PF14634.6 CBZ23286.1 - 0.00022 21.1 5.4 0.00071 19.5 5.4 2.0 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 CBZ23286.1 - 0.0005 19.9 5.0 0.0005 19.9 5.0 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CBZ23286.1 - 0.00064 20.0 7.7 0.00064 20.0 7.7 2.4 2 0 0 2 2 2 1 Ring finger domain EF-hand_8 PF13833.6 CBZ23286.1 - 0.0015 18.4 0.0 0.034 14.0 0.2 2.4 2 0 0 2 2 2 1 EF-hand domain pair Prok-RING_4 PF14447.6 CBZ23286.1 - 0.0019 18.0 7.4 0.0019 18.0 7.4 2.6 2 1 1 3 3 2 1 Prokaryotic RING finger family 4 zf-RING_6 PF14835.6 CBZ23286.1 - 0.082 12.8 4.1 0.073 13.0 2.0 2.1 2 1 0 2 2 2 0 zf-RING of BARD1-type protein Elf1 PF05129.13 CBZ23286.1 - 1.7 8.7 6.8 1.1 9.4 1.9 2.5 1 1 1 2 2 2 0 Transcription elongation factor Elf1 like DZR PF12773.7 CBZ23286.1 - 2.8 8.1 12.0 2.1 8.4 5.7 3.3 2 1 1 3 3 3 0 Double zinc ribbon TPR_19 PF14559.6 CBZ23287.1 - 1.4e-36 124.9 67.6 3.9e-06 27.3 3.7 15.2 9 5 6 15 15 15 10 Tetratricopeptide repeat TPR_2 PF07719.17 CBZ23287.1 - 4.5e-28 95.1 50.9 0.0038 17.2 0.2 20.4 22 0 0 22 22 22 5 Tetratricopeptide repeat TPR_16 PF13432.6 CBZ23287.1 - 1.2e-24 86.6 70.8 1e-05 26.0 7.6 13.8 13 1 1 14 14 12 9 Tetratricopeptide repeat TPR_1 PF00515.28 CBZ23287.1 - 3.6e-20 70.9 29.9 0.0014 18.4 0.3 13.7 15 0 0 15 15 13 4 Tetratricopeptide repeat TPR_14 PF13428.6 CBZ23287.1 - 1.4e-18 66.0 94.8 6.7e-05 23.4 0.8 21.8 13 8 12 25 25 23 5 Tetratricopeptide repeat TPR_8 PF13181.6 CBZ23287.1 - 4.9e-18 63.8 24.9 0.092 13.0 0.2 14.1 14 0 0 14 14 13 4 Tetratricopeptide repeat TPR_12 PF13424.6 CBZ23287.1 - 6.2e-11 42.4 74.7 1.5e-05 25.1 0.3 16.2 13 5 4 17 17 17 6 Tetratricopeptide repeat TPR_7 PF13176.6 CBZ23287.1 - 1.8e-09 36.9 34.4 0.6 10.3 0.0 13.1 16 0 0 16 16 12 4 Tetratricopeptide repeat TPR_17 PF13431.6 CBZ23287.1 - 6.2e-08 32.5 13.6 1.9 9.0 0.0 10.8 11 1 1 12 12 10 2 Tetratricopeptide repeat TPR_6 PF13174.6 CBZ23287.1 - 7.4e-08 32.6 65.1 0.052 14.2 0.1 18.6 21 0 0 21 21 20 2 Tetratricopeptide repeat TPR_4 PF07721.14 CBZ23287.1 - 1.2e-06 28.6 46.8 0.044 14.4 0.3 13.5 14 0 0 14 14 11 2 Tetratricopeptide repeat HrpB1_HrpK PF09613.10 CBZ23287.1 - 2.7e-05 23.8 26.0 0.012 15.2 0.7 7.8 7 2 1 8 8 8 3 Bacterial type III secretion protein (HrpB1_HrpK) TPR_11 PF13414.6 CBZ23287.1 - 4.4e-05 23.1 31.6 1.3 8.7 0.1 12.5 14 1 1 15 15 13 1 TPR repeat TPR_15 PF13429.6 CBZ23287.1 - 0.00059 19.1 1.2 0.00059 19.1 1.2 7.0 7 2 1 8 8 8 2 Tetratricopeptide repeat ANAPC3 PF12895.7 CBZ23287.1 - 0.0015 18.7 35.9 7.2 6.9 4.3 10.8 8 3 4 12 12 12 0 Anaphase-promoting complex, cyclosome, subunit 3 ChAPs PF09295.10 CBZ23287.1 - 0.0075 15.3 0.2 0.18 10.8 0.0 2.7 3 0 0 3 3 3 1 ChAPs (Chs5p-Arf1p-binding proteins) NARP1 PF12569.8 CBZ23287.1 - 0.016 14.2 7.1 2.9 6.7 0.0 5.2 6 1 1 7 7 7 0 NMDA receptor-regulated protein 1 RPN7 PF10602.9 CBZ23287.1 - 0.036 13.8 4.4 14 5.4 0.0 4.9 5 0 0 5 5 5 0 26S proteasome subunit RPN7 FAT PF02259.23 CBZ23287.1 - 0.057 12.6 0.1 5.8 6.0 0.0 3.5 2 1 0 2 2 2 0 FAT domain DUF2073 PF09846.9 CBZ23287.1 - 0.1 12.5 0.0 0.29 11.0 0.0 1.7 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2073) HsbA PF12296.8 CBZ23287.1 - 0.12 12.9 0.6 0.57 10.6 0.6 2.2 1 0 0 1 1 1 0 Hydrophobic surface binding protein A PPR PF01535.20 CBZ23287.1 - 0.36 11.2 5.8 6.7 7.2 0.0 5.6 7 0 0 7 7 4 0 PPR repeat MIT PF04212.18 CBZ23287.1 - 1.5 8.9 9.8 31 4.7 0.7 5.2 5 0 0 5 5 4 0 MIT (microtubule interacting and transport) domain Wzy_C_2 PF11846.8 CBZ23287.1 - 6.5 6.6 14.8 0.48 10.3 1.1 4.5 4 1 1 5 5 5 0 Virulence factor membrane-bound polymerase, C-terminal TPR_10 PF13374.6 CBZ23287.1 - 8.5 6.4 44.2 0.068 13.1 0.2 11.3 13 0 0 13 13 11 0 Tetratricopeptide repeat Y_phosphatase2 PF03162.13 CBZ23288.1 - 5.1e-51 172.5 0.0 6.7e-51 172.1 0.0 1.1 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3 PF13350.6 CBZ23288.1 - 4.1e-09 36.7 0.0 5.8e-09 36.3 0.0 1.3 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase PF00102.27 CBZ23288.1 - 0.01 15.4 0.0 0.015 14.9 0.0 1.3 1 0 0 1 1 1 0 Protein-tyrosine phosphatase DSPc PF00782.20 CBZ23288.1 - 0.058 13.2 0.0 0.087 12.6 0.0 1.3 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain DENN PF02141.21 CBZ23289.1 - 5.3e-10 39.5 1.7 1.1e-09 38.6 0.8 1.9 2 0 0 2 2 2 1 DENN (AEX-3) domain Spermine_synth PF01564.17 CBZ23290.1 - 2.4e-50 170.6 0.0 4.4e-50 169.7 0.0 1.4 2 0 0 2 2 2 1 Spermine/spermidine synthase domain Spermine_synt_N PF17284.2 CBZ23290.1 - 1.5e-12 47.2 0.0 3.3e-12 46.1 0.0 1.6 1 0 0 1 1 1 1 Spermidine synthase tetramerisation domain Methyltransf_25 PF13649.6 CBZ23290.1 - 0.0061 17.2 0.0 0.012 16.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain CRM1_repeat_2 PF18784.1 CBZ23290.1 - 0.083 12.5 0.0 0.21 11.2 0.0 1.7 1 0 0 1 1 1 0 CRM1 / Exportin repeat 2 Methyltransf_12 PF08242.12 CBZ23290.1 - 0.15 12.8 0.1 0.9 10.3 0.1 2.3 2 1 0 2 2 2 0 Methyltransferase domain BaxI_1 PF12811.7 CBZ23291.1 - 0.042 13.4 0.6 0.075 12.6 0.2 1.5 1 1 0 1 1 1 0 Bax inhibitor 1 like Claudin_2 PF13903.6 CBZ23291.1 - 0.055 13.2 0.5 0.41 10.4 0.0 2.4 2 1 1 3 3 3 0 PMP-22/EMP/MP20/Claudin tight junction DUF543 PF04418.12 CBZ23291.1 - 0.09 12.8 0.0 0.21 11.6 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF543) Glyco_trans_1_2 PF13524.6 CBZ23291.1 - 0.48 10.8 2.6 0.9 10.0 1.1 2.1 1 1 1 2 2 2 0 Glycosyl transferases group 1 Ank_2 PF12796.7 CBZ23292.1 - 5.9e-12 46.0 2.7 0.012 16.2 0.0 4.5 4 0 0 4 4 4 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CBZ23292.1 - 4.6e-11 43.0 0.6 0.071 13.7 0.0 5.5 4 1 1 5 5 5 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 CBZ23292.1 - 8e-09 35.6 9.2 0.013 15.9 0.2 4.8 5 0 0 5 5 5 3 Ankyrin repeats (many copies) Ank PF00023.30 CBZ23292.1 - 5.8e-08 32.8 11.4 0.043 14.3 0.2 6.5 6 0 0 6 6 6 3 Ankyrin repeat Ank_3 PF13606.6 CBZ23292.1 - 2.1e-07 30.7 6.9 0.17 12.5 0.0 5.6 6 0 0 6 6 6 2 Ankyrin repeat DUF4551 PF15087.6 CBZ23292.1 - 3.9 6.2 14.4 0.0054 15.6 2.6 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4551) Cwf_Cwc_15 PF04889.12 CBZ23293.1 - 0.0031 17.3 12.7 0.0037 17.0 12.7 1.2 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein DUF1168 PF06658.12 CBZ23293.1 - 0.0031 17.3 15.0 0.0041 16.9 15.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1168) Cu-oxidase_4 PF02578.15 CBZ23293.1 - 0.02 14.5 0.7 0.025 14.2 0.7 1.1 1 0 0 1 1 1 0 Multi-copper polyphenol oxidoreductase laccase TFIIA PF03153.13 CBZ23293.1 - 0.076 13.0 7.9 0.078 13.0 7.9 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit HAUS-augmin3 PF14932.6 CBZ23293.1 - 0.11 12.1 7.7 0.13 11.8 7.7 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 Vir_act_alpha_C PF10400.9 CBZ23293.1 - 0.21 12.3 9.3 0.14 12.8 6.3 2.3 1 1 2 3 3 3 0 Virulence activator alpha C-term DUF4603 PF15376.6 CBZ23293.1 - 0.81 7.0 11.7 0.96 6.8 11.7 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4603) MDFI PF15316.6 CBZ23293.1 - 3.4 7.7 7.1 5 7.2 7.1 1.3 1 0 0 1 1 1 0 MyoD family inhibitor ClpS PF02617.17 CBZ23294.1 - 0.23 11.3 0.2 7 6.5 0.0 2.6 2 0 0 2 2 2 0 ATP-dependent Clp protease adaptor protein ClpS PolyA_pol_RNAbd PF12627.7 CBZ23295.1 - 0.11 12.3 0.2 0.28 11.0 0.2 1.7 1 0 0 1 1 1 0 Probable RNA and SrmB- binding site of polymerase A TFIID-18kDa PF02269.16 CBZ23296.1 - 0.039 14.0 0.4 0.081 13.0 0.4 1.6 1 0 0 1 1 1 0 Transcription initiation factor IID, 18kD subunit DUF334 PF03904.13 CBZ23296.1 - 0.1 12.1 3.6 0.68 9.4 3.0 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF334) Pox_EPC_I2-L1 PF12575.8 CBZ23296.1 - 1.1 9.5 4.4 51 4.2 0.1 3.0 2 1 1 3 3 3 0 Poxvirus entry protein complex L1 and I2 zf-C3HC4_3 PF13920.6 CBZ23297.1 - 1.5e-08 34.4 9.2 2.7e-08 33.5 9.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CBZ23297.1 - 1.3e-06 28.2 9.7 2.2e-06 27.4 9.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CBZ23297.1 - 1.7e-05 25.0 12.8 3.7e-05 24.0 12.8 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 CBZ23297.1 - 0.02 14.7 11.6 0.048 13.5 11.6 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DAP10 PF07213.11 CBZ23297.1 - 0.057 13.4 0.6 0.5 10.3 0.1 2.4 2 0 0 2 2 2 0 DAP10 membrane protein zf-RING_UBOX PF13445.6 CBZ23297.1 - 0.13 12.3 11.9 0.44 10.6 11.8 2.0 1 1 0 1 1 1 0 RING-type zinc-finger Baculo_IE-1 PF05290.11 CBZ23297.1 - 0.66 9.9 4.1 1.3 9.0 4.1 1.4 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) zf-rbx1 PF12678.7 CBZ23297.1 - 1.2 9.5 7.1 2.6 8.4 7.1 1.5 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-RING_4 PF14570.6 CBZ23297.1 - 1.5 8.7 8.5 3.1 7.7 8.5 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Pkinase PF00069.25 CBZ23298.1 - 4.5e-38 131.1 0.0 4.8e-10 39.2 0.0 6.1 6 0 0 6 6 6 5 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ23298.1 - 3.6e-13 49.4 0.0 2.7e-08 33.4 0.0 4.0 4 0 0 4 4 4 3 Protein tyrosine kinase FHA PF00498.26 CBZ23298.1 - 2.4e-11 43.8 0.2 1.7e-10 41.1 0.2 2.1 1 1 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 CBZ23298.1 - 0.0092 16.3 0.2 4.6 7.6 0.0 2.7 2 0 0 2 2 2 2 Inner membrane component of T3SS, cytoplasmic domain FHA_2 PF17913.1 CBZ23298.1 - 0.063 13.5 0.0 0.13 12.5 0.0 1.4 1 0 0 1 1 1 0 FHA domain TGS PF02824.21 CBZ23298.1 - 0.16 12.1 0.2 0.78 9.8 0.1 2.3 2 0 0 2 2 2 0 TGS domain DUF2076 PF09849.9 CBZ23299.1 - 3.1e-05 24.2 3.8 3.6e-05 23.9 3.8 1.2 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2076) CHCH PF06747.13 CBZ23299.1 - 3.2e-05 23.9 1.9 4.4e-05 23.5 1.9 1.2 1 0 0 1 1 1 1 CHCH domain CX9C PF16860.5 CBZ23299.1 - 0.0026 17.7 0.6 0.004 17.1 0.6 1.3 1 0 0 1 1 1 1 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, DUF2076 PF09849.9 CBZ23300.1 - 4.7e-06 26.8 5.3 5.9e-06 26.5 5.3 1.2 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2076) CHCH PF06747.13 CBZ23300.1 - 3.3e-05 23.9 1.9 4.6e-05 23.4 1.9 1.2 1 0 0 1 1 1 1 CHCH domain CX9C PF16860.5 CBZ23300.1 - 0.0027 17.7 0.6 0.0042 17.1 0.6 1.3 1 0 0 1 1 1 1 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, UQ_con PF00179.26 CBZ23301.1 - 2.3e-46 157.0 0.1 2.5e-46 156.8 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 CBZ23301.1 - 0.004 16.9 0.0 0.0052 16.5 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.13 CBZ23301.1 - 0.0059 16.5 0.2 0.013 15.3 0.2 1.6 1 1 0 1 1 1 1 UEV domain Ax_dynein_light PF10211.9 CBZ23302.1 - 6.1e-10 39.3 7.7 2.9e-09 37.1 3.7 2.7 3 0 0 3 3 3 2 Axonemal dynein light chain CesT PF05932.13 CBZ23304.1 - 1.2e-09 38.3 0.1 2.9e-09 37.1 0.1 1.7 1 0 0 1 1 1 1 Tir chaperone protein (CesT) family PDZ_2 PF13180.6 CBZ23304.1 - 1.9e-09 37.7 0.0 2.7e-06 27.6 0.1 2.6 2 0 0 2 2 2 2 PDZ domain PDZ_6 PF17820.1 CBZ23304.1 - 1.4e-05 24.8 0.4 0.00068 19.4 0.1 2.7 2 0 0 2 2 2 1 PDZ domain PIG-S PF10510.9 CBZ23305.1 - 0.096 11.5 0.0 0.15 10.8 0.0 1.2 1 0 0 1 1 1 0 Phosphatidylinositol-glycan biosynthesis class S protein DUF974 PF06159.13 CBZ23306.1 - 7.3e-07 29.2 0.0 1.6e-06 28.1 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF974) WASH_WAHD PF11945.8 CBZ23307.1 - 3.7e-08 33.2 0.0 5.9e-08 32.6 0.0 1.2 1 0 0 1 1 1 1 WAHD domain of WASH complex Spt5_N PF11942.8 CBZ23307.1 - 0.7 10.9 9.1 2.1 9.4 9.1 1.8 1 0 0 1 1 1 0 Spt5 transcription elongation factor, acidic N-terminal Ribosomal_L16 PF00252.18 CBZ23308.1 - 7.7e-39 132.7 0.3 9.5e-39 132.4 0.3 1.1 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e DUF3212 PF11486.8 CBZ23308.1 - 0.17 11.9 0.0 0.25 11.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3212) NAC PF01849.18 CBZ23309.1 - 8.2e-16 57.7 0.5 1.4e-15 57.0 0.1 1.6 2 0 0 2 2 2 1 NAC domain Neuregulin PF02158.15 CBZ23309.1 - 0.0025 17.2 0.2 0.0032 16.9 0.2 1.3 1 0 0 1 1 1 1 Neuregulin intracellular region HOIP-UBA PF16678.5 CBZ23309.1 - 0.053 13.5 2.1 0.76 9.8 0.2 2.2 2 0 0 2 2 2 0 HOIP UBA domain pair PRIMA1 PF16101.5 CBZ23309.1 - 0.48 10.5 8.6 1 9.4 8.6 1.5 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 NAC PF01849.18 CBZ23310.1 - 2.7e-16 59.3 0.6 5.8e-16 58.2 0.1 1.8 2 0 0 2 2 2 1 NAC domain HOIP-UBA PF16678.5 CBZ23310.1 - 0.23 11.5 2.1 0.31 11.0 0.2 2.0 2 0 0 2 2 2 0 HOIP UBA domain pair Tmemb_185A PF10269.9 CBZ23311.1 - 5e-08 32.9 4.3 1.2e-07 31.7 2.3 2.7 1 1 1 2 2 2 2 Transmembrane Fragile-X-F protein Shisa PF13908.6 CBZ23311.1 - 0.0041 17.4 2.9 0.011 16.0 0.0 2.2 1 1 1 2 2 2 1 Wnt and FGF inhibitory regulator Sirohm_synth_C PF14823.6 CBZ23313.1 - 0.082 12.6 0.2 0.16 11.6 0.2 1.5 1 0 0 1 1 1 0 Sirohaem biosynthesis protein C-terminal Pescadillo_N PF06732.11 CBZ23314.1 - 5.7e-92 308.1 4.2 1.4e-91 306.9 4.2 1.6 1 0 0 1 1 1 1 Pescadillo N-terminus BRCT_2 PF16589.5 CBZ23314.1 - 1.4e-10 41.4 0.0 3.1e-10 40.3 0.0 1.6 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain LIG3_BRCT PF16759.5 CBZ23314.1 - 9.3e-06 25.9 0.0 2.7e-05 24.4 0.0 1.9 1 0 0 1 1 1 1 DNA ligase 3 BRCT domain BRCT PF00533.26 CBZ23314.1 - 0.00035 20.9 0.0 0.0013 19.0 0.0 2.1 1 1 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain Pep_deformylase PF01327.21 CBZ23315.1 - 8.6e-17 61.2 0.0 3.3e-16 59.3 0.0 1.9 1 1 0 1 1 1 1 Polypeptide deformylase DUF1523 PF07509.11 CBZ23315.1 - 0.11 11.9 0.0 0.18 11.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1523) Y_phosphatase2 PF03162.13 CBZ23317.1 - 2.1e-55 186.8 0.0 2.9e-55 186.3 0.0 1.2 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3 PF13350.6 CBZ23317.1 - 0.0041 17.1 0.0 0.0065 16.5 0.0 1.2 1 0 0 1 1 1 1 Tyrosine phosphatase family Rhomboid PF01694.22 CBZ23318.1 - 8.6e-09 35.6 1.8 2.1e-08 34.3 1.8 1.6 1 0 0 1 1 1 1 Rhomboid family Ribosomal_L30 PF00327.20 CBZ23319.1 - 4.3e-05 23.3 0.4 0.00012 21.9 0.0 2.0 2 0 0 2 2 2 1 Ribosomal protein L30p/L7e TPR_12 PF13424.6 CBZ23321.1 - 0.00035 20.8 1.2 0.032 14.5 0.1 3.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.6 CBZ23321.1 - 0.0014 18.7 0.2 0.0058 16.7 0.1 2.1 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_21 PF09976.9 CBZ23321.1 - 0.0056 16.4 0.1 0.013 15.2 0.1 1.6 1 0 0 1 1 1 1 Tetratricopeptide repeat-like domain TPR_11 PF13414.6 CBZ23321.1 - 0.013 15.1 0.3 0.029 14.0 0.3 1.6 1 0 0 1 1 1 0 TPR repeat TPR_2 PF07719.17 CBZ23321.1 - 0.019 15.0 0.6 0.04 14.0 0.0 1.9 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_1 PF00515.28 CBZ23321.1 - 0.022 14.6 0.1 0.075 12.9 0.1 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat IQ PF00612.27 CBZ23321.1 - 0.024 14.4 0.1 0.071 12.9 0.1 1.8 1 0 0 1 1 1 0 IQ calmodulin-binding motif CaMBD PF02888.16 CBZ23321.1 - 0.055 13.7 0.7 0.16 12.1 0.7 1.8 1 0 0 1 1 1 0 Calmodulin binding domain SPRR2 PF14820.6 CBZ23322.1 - 3.1 8.0 14.4 14 5.8 0.3 2.2 2 0 0 2 2 2 0 Small proline-rich 2 AAA_30 PF13604.6 CBZ23323.1 - 0.2 11.4 3.2 0.34 10.6 1.7 2.0 2 0 0 2 2 2 0 AAA domain Cmc1 PF08583.10 CBZ23324.1 - 0.00029 20.8 2.0 0.00042 20.3 2.0 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like Ndufs5 PF10200.9 CBZ23324.1 - 0.017 15.4 0.2 0.025 14.8 0.2 1.4 1 0 0 1 1 1 0 NADH:ubiquinone oxidoreductase, NDUFS5-15kDa DnaJ_C PF01556.18 CBZ23325.1 - 1.3e-35 122.7 0.1 1.7e-35 122.3 0.1 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 CBZ23325.1 - 5.3e-21 74.5 0.7 1e-20 73.6 0.4 1.6 2 0 0 2 2 2 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 CBZ23325.1 - 4.6e-08 33.3 23.2 9.4e-08 32.3 23.2 1.6 1 0 0 1 1 1 1 DnaJ central domain Anti-TRAP PF15777.5 CBZ23325.1 - 0.8 9.7 22.3 0.55 10.2 3.8 2.7 1 1 1 2 2 2 0 Tryptophan RNA-binding attenuator protein inhibitory protein Ribosomal_L16 PF00252.18 CBZ23326.1 - 7.7e-39 132.7 0.3 9.5e-39 132.4 0.3 1.1 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e DUF3212 PF11486.8 CBZ23326.1 - 0.17 11.9 0.0 0.25 11.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3212) ADK PF00406.22 CBZ23327.1 - 1.9e-38 132.0 0.0 2.3e-38 131.7 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 CBZ23327.1 - 3.9e-29 101.8 0.0 5.2e-29 101.4 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 CBZ23327.1 - 3.3e-06 27.7 0.0 5.9e-06 26.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 CBZ23327.1 - 1.7e-05 25.0 0.0 5.1e-05 23.5 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.6 CBZ23327.1 - 0.015 15.5 0.1 0.04 14.2 0.0 1.8 1 1 1 2 2 2 0 AAA domain dNK PF01712.19 CBZ23327.1 - 0.077 12.8 0.1 0.32 10.8 0.0 1.8 2 0 0 2 2 2 0 Deoxynucleoside kinase Cytidylate_kin PF02224.18 CBZ23327.1 - 0.089 12.5 0.0 0.37 10.5 0.0 1.9 2 0 0 2 2 2 0 Cytidylate kinase AAA_19 PF13245.6 CBZ23327.1 - 0.12 12.8 0.1 0.33 11.3 0.1 1.7 1 1 0 1 1 1 0 AAA domain Nop14 PF04147.12 CBZ23331.1 - 1.9e-05 23.2 24.0 2.4e-05 22.8 24.0 1.1 1 0 0 1 1 1 1 Nop14-like family SDA1 PF05285.12 CBZ23331.1 - 0.0014 18.2 25.7 0.0019 17.7 25.7 1.2 1 0 0 1 1 1 1 SDA1 CDC45 PF02724.14 CBZ23331.1 - 0.0016 16.9 17.0 0.002 16.5 17.0 1.1 1 0 0 1 1 1 1 CDC45-like protein BUD22 PF09073.10 CBZ23331.1 - 0.014 14.7 26.0 0.019 14.3 26.0 1.2 1 0 0 1 1 1 0 BUD22 Pes-10 PF07149.11 CBZ23331.1 - 0.029 13.4 17.9 0.04 13.0 17.9 1.2 1 0 0 1 1 1 0 Pes-10 Mpp10 PF04006.12 CBZ23331.1 - 0.12 10.8 22.8 0.16 10.3 22.8 1.1 1 0 0 1 1 1 0 Mpp10 protein Na_trans_assoc PF06512.13 CBZ23331.1 - 0.18 12.0 13.2 0.26 11.5 13.2 1.3 1 0 0 1 1 1 0 Sodium ion transport-associated PNISR PF15996.5 CBZ23331.1 - 0.37 11.0 12.3 0.63 10.3 12.3 1.3 1 0 0 1 1 1 0 Arginine/serine-rich protein PNISR TFIIF_alpha PF05793.12 CBZ23331.1 - 0.38 9.3 24.8 0.54 8.8 24.8 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Zip PF02535.22 CBZ23331.1 - 0.92 8.7 4.6 1.2 8.3 4.6 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Roughex PF06020.11 CBZ23331.1 - 1.4 8.0 16.4 2 7.5 16.4 1.2 1 0 0 1 1 1 0 Drosophila roughex protein SURF2 PF05477.11 CBZ23331.1 - 1.5 8.4 15.3 2.2 7.9 15.3 1.2 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) Hid1 PF12722.7 CBZ23331.1 - 1.5 6.8 6.3 1.9 6.5 6.3 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein SAPS PF04499.15 CBZ23331.1 - 3.3 6.4 10.2 3.9 6.2 10.2 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Presenilin PF01080.17 CBZ23331.1 - 5.2 5.7 7.3 6.3 5.4 7.3 1.1 1 0 0 1 1 1 0 Presenilin Voltage_CLC PF00654.20 CBZ23332.1 - 2.4e-87 293.5 30.1 2.4e-87 293.5 30.1 1.8 1 1 1 2 2 2 1 Voltage gated chloride channel CBS PF00571.28 CBZ23332.1 - 6.7e-07 29.7 1.4 0.038 14.4 0.0 3.4 3 0 0 3 3 3 2 CBS domain TAT_signal PF10518.9 CBZ23332.1 - 0.27 11.1 5.9 0.094 12.6 0.4 3.0 2 0 0 2 2 2 0 TAT (twin-arginine translocation) pathway signal sequence RRP36 PF06102.12 CBZ23333.1 - 3e-23 82.6 10.0 6.3e-23 81.6 10.0 1.5 1 1 0 1 1 1 1 rRNA biogenesis protein RRP36 COPI_assoc PF08507.10 CBZ23334.1 - 2.7e-06 27.5 11.5 3.7e-06 27.0 11.5 1.2 1 0 0 1 1 1 1 COPI associated protein Neurensin PF14927.6 CBZ23334.1 - 0.24 11.1 4.8 1.4 8.6 0.2 2.6 2 1 0 2 2 2 0 Neurensin IncD PF17628.2 CBZ23334.1 - 0.37 10.6 0.1 0.37 10.6 0.1 1.8 2 0 0 2 2 2 0 Inclusion membrane protein D DUF3671 PF12420.8 CBZ23334.1 - 0.99 9.5 5.8 1.1 9.4 3.7 1.9 1 1 1 2 2 2 0 Protein of unknown function Acyltransferase PF01553.21 CBZ23336.1 - 9.5e-11 41.5 0.1 1.4e-10 41.0 0.1 1.3 1 0 0 1 1 1 1 Acyltransferase DEC-1_N PF04625.13 CBZ23337.1 - 0.43 9.5 5.0 0.26 10.3 2.4 1.8 1 1 0 1 1 1 0 DEC-1 protein, N-terminal region Macoilin PF09726.9 CBZ23337.1 - 4 5.9 4.1 0.57 8.7 0.0 1.5 2 0 0 2 2 2 0 Macoilin family FliG_C PF01706.16 CBZ23338.1 - 0.084 13.1 0.3 0.11 12.8 0.3 1.3 1 0 0 1 1 1 0 FliG C-terminal domain Tcf25 PF04910.14 CBZ23339.1 - 2e-38 132.4 0.0 3.3e-38 131.7 0.0 1.2 1 0 0 1 1 1 1 Transcriptional repressor TCF25 Rrn6 PF10214.9 CBZ23339.1 - 0.096 11.2 14.6 0.16 10.4 14.6 1.3 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor DUF3292 PF11696.8 CBZ23339.1 - 4.7 5.5 8.8 7.4 4.8 8.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3292) BAF1_ABF1 PF04684.13 CBZ23339.1 - 4.7 6.1 10.9 8.1 5.4 10.9 1.3 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor SRP-alpha_N PF04086.13 CBZ23339.1 - 8.6 6.2 22.8 42 3.9 21.5 2.2 2 0 0 2 2 2 0 Signal recognition particle, alpha subunit, N-terminal PKcGMP_CC PF16808.5 CBZ23340.1 - 0.077 12.9 12.3 0.38 10.6 2.4 4.2 3 0 0 3 3 3 0 Coiled-coil N-terminus of cGMP-dependent protein kinase UpxZ PF06603.11 CBZ23340.1 - 0.23 11.8 2.2 0.64 10.3 1.4 2.2 1 1 0 1 1 1 0 UpxZ family of transcription anti-terminator antagonists Ribosomal_L41 PF05162.13 CBZ23341.1 - 0.15 12.2 0.4 0.31 11.1 0.4 1.6 1 0 0 1 1 1 0 Ribosomal protein L41 E1-E2_ATPase PF00122.20 CBZ23342.1 - 1.8e-22 79.7 0.1 1.8e-22 79.7 0.1 2.0 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.26 CBZ23342.1 - 2.3e-13 50.9 0.5 1.8e-06 28.4 0.2 2.4 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase 3HCDH_RFF PF18321.1 CBZ23342.1 - 5.2 7.6 10.3 0.39 11.2 0.7 3.9 3 0 0 3 3 3 0 3-hydroxybutyryl-CoA dehydrogenase reduced Rossmann-fold domain Transglut_i_TM PF14400.6 CBZ23343.1 - 1.4 9.0 6.2 0.39 10.8 1.2 2.4 2 0 0 2 2 2 0 Inactive transglutaminase fused to 7 transmembrane helices TINF2_N PF14973.6 CBZ23343.1 - 1.6 9.1 8.0 0.16 12.3 1.3 2.5 3 1 0 3 3 3 0 TERF1-interacting nuclear factor 2 N-terminus DUF1664 PF07889.12 CBZ23343.1 - 9.4 6.3 11.0 0.24 11.4 2.1 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) SCO1-SenC PF02630.14 CBZ23344.1 - 1.7e-44 151.0 0.0 2.5e-44 150.5 0.0 1.2 1 0 0 1 1 1 1 SCO1/SenC AhpC-TSA PF00578.21 CBZ23344.1 - 0.012 15.5 0.0 0.023 14.6 0.0 1.5 1 0 0 1 1 1 0 AhpC/TSA family ETS_PEA3_N PF04621.13 CBZ23345.1 - 0.2 11.5 5.1 0.24 11.2 3.9 1.5 1 1 0 1 1 1 0 PEA3 subfamily ETS-domain transcription factor N terminal domain Phage_T4_Ndd PF06591.11 CBZ23346.1 - 0.012 15.4 0.0 0.017 14.9 0.0 1.2 1 0 0 1 1 1 0 T4-like phage nuclear disruption protein (Ndd) FBPase PF00316.20 CBZ23347.1 - 1.7e-54 184.2 0.2 2.2e-54 183.8 0.2 1.1 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase, N-terminal domain NdhM PF10664.9 CBZ23347.1 - 0.086 13.1 0.0 0.19 12.0 0.0 1.5 1 0 0 1 1 1 0 Cyanobacterial and plastid NDH-1 subunit M RRM_1 PF00076.22 CBZ23349.1 - 2.2e-13 49.8 0.0 1.3e-05 24.9 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 CBZ23349.1 - 5.4e-09 35.7 0.1 0.00038 20.1 0.1 2.4 1 1 1 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 CBZ23349.1 - 0.00023 21.0 0.2 0.0039 17.0 0.1 2.5 2 1 0 2 2 2 1 Occluded RNA-recognition motif CDC48_2 PF02933.17 CBZ23349.1 - 0.0023 17.7 0.0 0.0042 16.8 0.0 1.5 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), domain 2 RRM_8 PF11835.8 CBZ23349.1 - 0.0037 17.4 0.1 0.013 15.7 0.1 1.9 2 0 0 2 2 2 1 RRM-like domain DUF5399 PF17377.2 CBZ23349.1 - 0.052 13.4 0.4 0.12 12.1 0.1 1.7 2 0 0 2 2 2 0 Family of unknown function (DUF5399) MOEP19 PF16005.5 CBZ23349.1 - 0.14 12.2 0.3 0.54 10.3 0.1 2.0 2 0 0 2 2 2 0 KH-like RNA-binding domain PolyA_pol PF01743.20 CBZ23351.1 - 6.7e-29 100.9 0.0 1.2e-28 100.0 0.0 1.5 1 0 0 1 1 1 1 Poly A polymerase head domain PolyA_pol_RNAbd PF12627.7 CBZ23351.1 - 7.8e-07 28.8 0.0 1.9e-06 27.5 0.0 1.6 1 0 0 1 1 1 1 Probable RNA and SrmB- binding site of polymerase A LRR_6 PF13516.6 CBZ23352.1 - 1.5e-05 24.7 0.1 0.19 11.9 0.0 3.5 4 0 0 4 4 4 2 Leucine Rich repeat LRR_4 PF12799.7 CBZ23352.1 - 0.011 16.1 0.4 0.11 13.0 0.2 2.5 1 1 0 2 2 2 0 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CBZ23352.1 - 0.029 14.1 0.1 1.9 8.3 0.1 2.7 2 1 1 3 3 3 0 Leucine rich repeat US6 PF17616.2 CBZ23352.1 - 0.03 14.3 0.0 0.042 13.8 0.0 1.2 1 0 0 1 1 1 0 Viral unique short region 6 Pkinase PF00069.25 CBZ23353.1 - 9.3e-26 90.8 0.0 1.2e-25 90.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ23353.1 - 1.3e-17 63.9 0.0 2e-17 63.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CBZ23353.1 - 2.6e-07 29.8 0.1 3.5e-07 29.3 0.1 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 CBZ23353.1 - 0.015 14.6 0.0 0.024 14.0 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Actin PF00022.19 CBZ23355.1 - 2.4e-136 454.6 0.0 2.1e-135 451.4 0.0 1.9 1 1 0 1 1 1 1 Actin ATG16 PF08614.11 CBZ23356.1 - 0.0046 17.2 21.8 0.0046 17.2 21.8 7.9 3 2 3 7 7 7 2 Autophagy protein 16 (ATG16) Cation_ATPase PF13246.6 CBZ23356.1 - 0.043 13.9 1.0 12 6.0 0.2 3.4 2 0 0 2 2 2 0 Cation transport ATPase (P-type) Peptidase_S7 PF00949.21 CBZ23356.1 - 0.17 11.7 0.1 1.2 9.0 0.0 2.5 2 1 1 3 3 3 0 Peptidase S7, Flavivirus NS3 serine protease DUF3502 PF12010.8 CBZ23356.1 - 1.3 9.6 5.8 0.65 10.6 1.3 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF3502) Arf PF00025.21 CBZ23358.1 - 3.8e-54 182.8 0.0 4.3e-54 182.6 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.20 CBZ23358.1 - 8.6e-09 35.0 0.8 6.5e-06 25.5 0.0 2.6 1 1 1 2 2 2 2 G-protein alpha subunit SRPRB PF09439.10 CBZ23358.1 - 2.6e-08 33.5 0.0 3.4e-08 33.1 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 CBZ23358.1 - 6.6e-08 32.6 0.0 1.2e-07 31.8 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Roc PF08477.13 CBZ23358.1 - 7.4e-08 32.6 0.0 1.8e-07 31.4 0.0 1.6 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 CBZ23358.1 - 2.7e-07 30.3 0.0 3.4e-07 30.0 0.0 1.1 1 0 0 1 1 1 1 Ras family GTP_EFTU PF00009.27 CBZ23358.1 - 5.5e-05 22.8 0.1 0.019 14.5 0.0 2.1 1 1 1 2 2 2 2 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 CBZ23358.1 - 0.00018 20.9 0.0 0.00023 20.6 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region cobW PF02492.19 CBZ23358.1 - 0.014 15.0 0.1 1 8.9 0.0 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain FeoB_N PF02421.18 CBZ23358.1 - 0.04 13.4 0.0 0.22 11.1 0.0 1.9 1 1 0 1 1 1 0 Ferrous iron transport protein B SRP54 PF00448.22 CBZ23358.1 - 0.068 12.8 0.2 0.15 11.7 0.2 1.5 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain Bacillus_HBL PF05791.11 CBZ23359.1 - 3.6 7.4 27.5 0.061 13.2 1.6 5.3 3 2 1 5 5 5 0 Bacillus haemolytic enterotoxin (HBL) eIF3_N PF09440.10 CBZ23360.1 - 0.0065 16.9 2.3 0.0065 16.9 2.3 4.9 2 2 3 5 5 5 1 eIF3 subunit 6 N terminal domain MVP_shoulder PF11978.8 CBZ23361.1 - 6.1e-48 161.7 0.1 1.1e-47 160.9 0.1 1.5 1 0 0 1 1 1 1 Shoulder domain Vault PF01505.18 CBZ23361.1 - 3.3e-46 155.2 3.5 3.3e-12 46.4 0.1 4.8 4 0 0 4 4 4 4 Major Vault Protein repeat domain Vault_3 PF17795.1 CBZ23361.1 - 8.3e-32 109.0 1.8 3.6e-30 103.8 0.1 3.3 3 0 0 3 3 3 1 Major Vault Protein Repeat domain Vault_2 PF17794.1 CBZ23361.1 - 6e-28 97.0 0.3 1.8e-20 73.0 0.2 2.9 2 0 0 2 2 2 2 Major Vault Protein repeat domain Vault_4 PF17796.1 CBZ23361.1 - 1.1e-20 73.4 0.1 5.7e-20 71.1 0.1 2.2 2 0 0 2 2 2 1 Major Vault Protein repeat domain DUF3601 PF12208.8 CBZ23361.1 - 0.081 13.0 0.0 4.6 7.4 0.0 3.1 2 1 1 3 3 3 0 Domain of unknown function (DUF3601) Dynein_light PF01221.18 CBZ23362.1 - 7.7e-30 103.1 0.7 9e-30 102.8 0.7 1.0 1 0 0 1 1 1 1 Dynein light chain type 1 Vasohibin PF14822.6 CBZ23362.1 - 0.0027 17.0 0.1 0.0033 16.7 0.1 1.3 1 1 0 1 1 1 1 Vasohibin Rrp15p PF07890.12 CBZ23363.1 - 3.5e-10 40.3 10.0 8.4e-10 39.1 10.0 1.6 1 1 0 1 1 1 1 Rrp15p NUDIX PF00293.28 CBZ23364.1 - 4.6e-15 55.8 0.0 7.4e-15 55.1 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain Metallophos PF00149.28 CBZ23365.1 - 2.9e-26 93.2 0.1 4.5e-26 92.6 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Plus-3 PF03126.18 CBZ23365.1 - 1.5e-06 28.6 0.0 2.9e-06 27.8 0.0 1.5 1 0 0 1 1 1 1 Plus-3 domain Methyltransf_4 PF02390.17 CBZ23367.1 - 0.019 14.5 0.0 0.027 13.9 0.0 1.2 1 0 0 1 1 1 0 Putative methyltransferase GspL_C PF12693.7 CBZ23367.1 - 0.044 13.6 0.1 0.089 12.6 0.1 1.5 1 0 0 1 1 1 0 GspL periplasmic domain Pkinase PF00069.25 CBZ23368.1 - 4.1e-56 190.3 0.0 6.4e-56 189.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ23368.1 - 2e-29 102.7 0.0 3.1e-26 92.2 0.1 2.1 1 1 1 2 2 2 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 CBZ23368.1 - 6.7e-06 25.1 0.0 8.2e-06 24.8 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 CBZ23368.1 - 0.001 19.1 0.1 0.0076 16.2 0.0 2.0 1 1 1 2 2 2 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 CBZ23368.1 - 0.0034 16.4 0.4 0.0053 15.8 0.4 1.2 1 0 0 1 1 1 1 Haspin like kinase domain YrbL-PhoP_reg PF10707.9 CBZ23368.1 - 0.0071 15.9 0.1 0.011 15.3 0.1 1.3 1 0 0 1 1 1 1 PhoP regulatory network protein YrbL RIO1 PF01163.22 CBZ23368.1 - 0.033 13.8 1.0 0.062 12.9 0.4 1.6 1 1 0 1 1 1 0 RIO1 family Kinase-like PF14531.6 CBZ23368.1 - 0.08 12.2 0.1 6.4 6.0 0.0 2.2 2 0 0 2 2 2 0 Kinase-like DEAD PF00270.29 CBZ23369.1 - 8e-41 139.7 0.0 2.5e-40 138.1 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CBZ23369.1 - 9.3e-31 106.5 0.0 1.8e-28 99.1 0.0 2.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain GUCT PF08152.12 CBZ23369.1 - 2.9e-19 69.1 0.0 7.6e-19 67.8 0.0 1.7 1 0 0 1 1 1 1 GUCT (NUC152) domain ERCC3_RAD25_C PF16203.5 CBZ23369.1 - 0.00012 21.3 0.0 0.00021 20.6 0.0 1.3 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase ResIII PF04851.15 CBZ23369.1 - 0.091 12.8 0.0 0.21 11.6 0.0 1.6 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit LRR_6 PF13516.6 CBZ23370.1 - 2.4e-33 111.3 27.5 1.5e-05 24.6 0.1 9.8 11 0 0 11 11 11 6 Leucine Rich repeat LRR_4 PF12799.7 CBZ23370.1 - 8.2e-11 42.0 10.5 2.2e-05 24.7 0.1 5.4 5 2 2 7 7 7 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 CBZ23370.1 - 2.8e-10 39.3 0.0 3.4 8.6 0.0 7.2 7 0 0 7 7 7 2 Leucine Rich Repeat LRR_8 PF13855.6 CBZ23370.1 - 2.6e-05 23.9 10.2 0.21 11.4 0.7 5.8 5 2 0 5 5 5 2 Leucine rich repeat IFRD PF05004.13 CBZ23370.1 - 9.7e-05 21.6 1.1 0.00013 21.2 1.1 1.2 1 0 0 1 1 1 1 Interferon-related developmental regulator (IFRD) DUF2524 PF10732.9 CBZ23371.1 - 0.0047 17.2 14.2 0.0047 17.2 14.2 4.4 3 1 1 4 4 4 1 Protein of unknown function (DUF2524) DUF812 PF05667.11 CBZ23371.1 - 0.5 9.2 33.5 0.53 9.1 12.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF812) Lebercilin PF15619.6 CBZ23371.1 - 1.5 8.5 53.1 0.44 10.2 16.9 3.1 3 0 0 3 3 3 0 Ciliary protein causing Leber congenital amaurosis disease 2-oxoacid_dh PF00198.23 CBZ23373.1 - 4.4e-81 271.7 0.1 5.6e-81 271.4 0.1 1.1 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 CBZ23373.1 - 1.1e-16 60.5 2.3 1.3e-16 60.2 0.3 2.2 3 0 0 3 3 3 1 Biotin-requiring enzyme E3_binding PF02817.17 CBZ23373.1 - 1.9e-15 56.9 0.1 5.3e-15 55.5 0.1 1.8 1 0 0 1 1 1 1 e3 binding domain Biotin_lipoyl_2 PF13533.6 CBZ23373.1 - 0.1 12.5 2.4 21 5.0 0.0 3.3 3 0 0 3 3 3 0 Biotin-lipoyl like Fip1 PF05182.13 CBZ23374.1 - 1.8e-18 65.7 0.3 3.2e-18 65.0 0.3 1.4 1 0 0 1 1 1 1 Fip1 motif zf-CCCH PF00642.24 CBZ23374.1 - 1.2e-10 41.0 3.0 2.5e-10 40.0 3.0 1.6 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 CBZ23374.1 - 2.3e-05 24.3 5.1 4e-05 23.5 5.1 1.4 1 0 0 1 1 1 1 Zinc finger domain zf-CCCH_4 PF18044.1 CBZ23374.1 - 4.8e-05 23.0 3.3 8.4e-05 22.3 3.3 1.4 1 0 0 1 1 1 1 CCCH-type zinc finger Torus PF16131.5 CBZ23374.1 - 0.00074 20.2 1.0 0.0015 19.2 1.0 1.4 1 0 0 1 1 1 1 Torus domain zf-CCCH_2 PF14608.6 CBZ23374.1 - 0.043 14.3 2.3 0.074 13.5 2.3 1.4 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger MMR_HSR1 PF01926.23 CBZ23375.1 - 1.2e-14 54.4 0.0 1.2e-13 51.1 0.0 2.4 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 CBZ23375.1 - 4.5e-06 26.3 0.0 1.6e-05 24.5 0.0 1.9 2 0 0 2 2 2 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 CBZ23375.1 - 4e-05 23.6 0.0 0.39 10.6 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase AIG1 PF04548.16 CBZ23375.1 - 0.00027 20.3 0.0 0.00054 19.4 0.0 1.5 1 0 0 1 1 1 1 AIG1 family Dynamin_N PF00350.23 CBZ23375.1 - 0.61 10.1 2.2 0.79 9.8 0.1 2.3 2 1 0 2 2 2 0 Dynamin family AAA_16 PF13191.6 CBZ23375.1 - 2.6 8.4 7.1 1 9.7 0.0 3.4 2 2 0 2 2 2 0 AAA ATPase domain MAGE_N PF12440.8 CBZ23376.1 - 1.6 9.5 0.0 1.6 9.5 0.0 6.3 6 1 1 7 7 7 0 Melanoma associated antigen family N terminal DSPc PF00782.20 CBZ23377.1 - 6.6e-33 113.3 0.1 1.1e-32 112.7 0.1 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 CBZ23377.1 - 6.6e-05 22.6 0.0 0.00012 21.7 0.0 1.5 1 1 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase2 PF03162.13 CBZ23377.1 - 0.00079 19.0 0.0 0.0013 18.3 0.0 1.3 1 0 0 1 1 1 1 Tyrosine phosphatase family Init_tRNA_PT PF04179.12 CBZ23377.1 - 0.029 14.7 0.0 0.071 13.4 0.0 1.6 1 0 0 1 1 1 0 Rit1 DUSP-like domain CDKN3 PF05706.12 CBZ23377.1 - 0.054 13.2 0.0 0.61 9.7 0.0 2.2 2 0 0 2 2 2 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) Fe_hyd_lg_C PF02906.14 CBZ23378.1 - 3.3e-54 184.1 0.0 1.4e-53 182.1 0.0 1.9 1 1 1 2 2 2 1 Iron only hydrogenase large subunit, C-terminal domain DUF742 PF05331.11 CBZ23378.1 - 0.056 13.3 0.7 2 8.3 0.1 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF742) PDZ_6 PF17820.1 CBZ23379.1 - 0.00023 20.9 2.8 0.0008 19.2 0.1 3.6 3 0 0 3 3 3 1 PDZ domain PDZ PF00595.24 CBZ23379.1 - 0.0042 17.4 0.0 0.0085 16.4 0.0 1.5 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 CBZ23379.1 - 0.013 15.8 0.0 0.028 14.7 0.0 1.5 1 0 0 1 1 1 0 PDZ domain PDZ_6 PF17820.1 CBZ23380.1 - 2.7e-05 23.9 0.1 0.001 18.9 0.1 4.0 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 CBZ23380.1 - 0.0052 17.1 0.0 0.011 16.0 0.0 1.6 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 CBZ23380.1 - 0.017 15.5 0.0 0.037 14.4 0.0 1.5 1 0 0 1 1 1 0 PDZ domain Ank_3 PF13606.6 CBZ23382.1 - 1.5e-05 25.0 0.0 6.7e-05 23.0 0.0 2.1 2 0 0 2 2 2 1 Ankyrin repeat Ank_5 PF13857.6 CBZ23382.1 - 2.3e-05 24.6 0.0 7.5e-05 22.9 0.0 1.9 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 CBZ23382.1 - 0.0002 21.9 0.0 0.0015 19.1 0.0 2.4 3 0 0 3 3 3 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CBZ23382.1 - 0.00024 21.6 0.1 0.0007 20.1 0.1 1.9 1 1 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.30 CBZ23382.1 - 0.0037 17.6 0.0 0.0093 16.4 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeat Med8 PF10232.9 CBZ23383.1 - 0.003 17.2 4.2 0.37 10.3 0.3 2.2 2 0 0 2 2 2 2 Mediator of RNA polymerase II transcription complex subunit 8 SasG_E PF17041.5 CBZ23383.1 - 0.061 13.3 0.1 5.4 7.1 0.2 2.5 2 0 0 2 2 2 0 E domain K_channel_TID PF07941.11 CBZ23383.1 - 0.22 12.0 2.8 0.55 10.7 2.8 1.7 1 0 0 1 1 1 0 Potassium channel Kv1.4 tandem inactivation domain PTPLA PF04387.14 CBZ23384.1 - 2.1e-56 190.2 6.9 2.7e-56 189.8 6.9 1.2 1 0 0 1 1 1 1 Protein tyrosine phosphatase-like protein, PTPLA P16-Arc PF04699.14 CBZ23385.1 - 6.9e-05 23.4 0.0 9.6e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 ARP2/3 complex 16 kDa subunit (p16-Arc) Mito_carr PF00153.27 CBZ23386.1 - 2.9e-40 136.1 12.5 3.1e-14 52.7 0.0 4.5 5 0 0 5 5 5 3 Mitochondrial carrier protein zf-NF-X1 PF01422.17 CBZ23387.1 - 3.7 7.7 5.5 7.4 6.7 0.7 2.7 2 0 0 2 2 2 0 NF-X1 type zinc finger Glutaredoxin PF00462.24 CBZ23388.1 - 3e-15 56.2 0.0 4.4e-15 55.7 0.0 1.3 1 0 0 1 1 1 1 Glutaredoxin MCM PF00493.23 CBZ23390.1 - 8.6e-69 231.1 0.0 1.2e-68 230.5 0.0 1.2 1 0 0 1 1 1 1 MCM P-loop domain MCM_lid PF17855.1 CBZ23390.1 - 2.8e-15 56.5 0.3 4e-09 36.8 0.6 2.4 2 0 0 2 2 2 2 MCM AAA-lid domain MCM_OB PF17207.3 CBZ23390.1 - 1e-09 38.3 1.1 8.7e-09 35.3 0.3 2.3 2 0 0 2 2 2 1 MCM OB domain AAA_5 PF07728.14 CBZ23390.1 - 8.2e-09 35.6 0.0 1.6e-08 34.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 CBZ23390.1 - 0.00022 20.7 0.2 0.076 12.4 0.2 2.5 1 1 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 CBZ23390.1 - 0.00049 20.0 0.0 0.0013 18.6 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 CBZ23390.1 - 0.0098 15.6 0.1 0.042 13.6 0.1 1.9 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA PF00004.29 CBZ23390.1 - 0.049 14.1 0.0 0.13 12.7 0.0 1.8 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 CBZ23390.1 - 0.14 12.5 0.5 0.38 11.1 0.1 2.0 2 0 0 2 2 2 0 AAA ATPase domain AAA_2 PF07724.14 CBZ23390.1 - 0.21 11.7 0.0 0.4 10.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) AAA_lid_2 PF17863.1 CBZ23390.1 - 7.8 6.4 12.1 0.051 13.4 1.7 2.8 3 0 0 3 3 3 0 AAA lid domain Ribosomal_S11 PF00411.19 CBZ23391.1 - 0.00011 22.6 1.3 0.00029 21.2 0.1 2.3 3 0 0 3 3 3 1 Ribosomal protein S11 Pyr_redox_2 PF07992.14 CBZ23392.1 - 1.1e-60 205.4 0.3 1.4e-60 205.1 0.3 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 CBZ23392.1 - 1.3e-25 89.8 0.1 2.6e-25 88.8 0.1 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 CBZ23392.1 - 1e-19 70.9 0.2 1.1e-16 61.2 0.0 2.7 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 CBZ23392.1 - 3.1e-12 46.4 0.1 8.3e-10 38.4 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 CBZ23392.1 - 4.6e-06 25.6 0.6 0.065 11.9 0.0 2.4 2 0 0 2 2 2 2 HI0933-like protein FAD_binding_2 PF00890.24 CBZ23392.1 - 6.2e-05 22.3 2.7 0.00058 19.1 1.6 2.5 2 1 1 3 3 3 1 FAD binding domain GIDA PF01134.22 CBZ23392.1 - 0.0053 15.9 0.7 0.0089 15.1 0.1 1.7 2 0 0 2 2 2 1 Glucose inhibited division protein A Thi4 PF01946.17 CBZ23392.1 - 0.068 12.4 0.1 0.14 11.4 0.1 1.5 1 0 0 1 1 1 0 Thi4 family NAD_binding_9 PF13454.6 CBZ23392.1 - 0.095 12.7 0.4 0.26 11.3 0.0 1.8 2 0 0 2 2 2 0 FAD-NAD(P)-binding DAO PF01266.24 CBZ23392.1 - 0.11 12.1 0.5 11 5.5 0.2 2.7 3 0 0 3 3 3 0 FAD dependent oxidoreductase DEAD PF00270.29 CBZ23393.1 - 2.8e-43 147.7 0.0 5e-43 146.9 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CBZ23393.1 - 3.1e-24 85.4 0.0 8.1e-24 84.1 0.0 1.7 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 CBZ23393.1 - 7.1e-05 22.9 0.0 0.00017 21.7 0.0 1.6 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 CBZ23393.1 - 0.022 15.1 0.1 0.066 13.5 0.1 1.9 1 1 0 1 1 1 0 AAA domain YaeQ PF07152.12 CBZ23394.1 - 0.012 15.2 0.1 4.4 6.9 0.0 2.2 2 0 0 2 2 2 0 YaeQ protein DUF1143 PF06608.11 CBZ23394.1 - 0.088 12.9 0.3 0.64 10.1 0.0 2.4 2 1 1 3 3 3 0 Protein of unknown function (DUF1143) Phage_TAC_5 PF08890.11 CBZ23395.1 - 0.0047 16.9 14.4 33 4.5 0.0 11.1 1 1 15 17 17 17 2 Phage XkdN-like tail assembly chaperone protein, TAC Pkinase PF00069.25 CBZ23396.1 - 1.5e-68 231.0 0.0 1.9e-68 230.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ23396.1 - 2.8e-49 167.7 0.0 4.1e-49 167.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase MORN PF02493.20 CBZ23396.1 - 2.5e-42 140.3 49.1 4.2e-10 38.9 3.8 8.6 8 0 0 8 8 8 8 MORN repeat Pkinase_fungal PF17667.1 CBZ23396.1 - 0.0001 21.2 0.0 0.00015 20.7 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 CBZ23396.1 - 0.0027 17.1 0.0 0.0089 15.4 0.0 1.8 2 1 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 CBZ23396.1 - 0.0047 15.9 0.0 0.0077 15.2 0.0 1.3 1 0 0 1 1 1 1 Haspin like kinase domain RIO1 PF01163.22 CBZ23396.1 - 0.066 12.8 0.0 0.36 10.4 0.0 1.9 2 0 0 2 2 2 0 RIO1 family APH PF01636.23 CBZ23396.1 - 0.097 12.6 0.0 1.2 9.0 0.1 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family ABC1 PF03109.16 CBZ23396.1 - 0.12 12.6 0.0 0.23 11.7 0.0 1.4 1 0 0 1 1 1 0 ABC1 family SMC_N PF02463.19 CBZ23397.1 - 6.1e-59 199.1 0.0 1.1e-58 198.3 0.0 1.5 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 CBZ23397.1 - 3.3e-13 50.1 0.2 1e-05 25.5 0.0 2.8 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 CBZ23397.1 - 3.8e-10 40.6 17.4 3.8e-10 40.6 17.4 6.7 2 2 1 3 3 3 1 AAA domain SMC_hinge PF06470.13 CBZ23397.1 - 1.4e-09 38.3 0.1 7.1e-09 36.0 0.0 2.4 2 1 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_15 PF13175.6 CBZ23397.1 - 3.2e-08 33.7 2.8 4.9e-06 26.5 0.0 3.9 2 2 0 2 2 2 1 AAA ATPase domain AAA_29 PF13555.6 CBZ23397.1 - 9.2e-05 22.1 0.0 0.00024 20.8 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain ABC_tran PF00005.27 CBZ23397.1 - 0.032 14.7 17.3 1.6 9.3 3.2 5.8 3 2 0 3 3 3 0 ABC transporter TPR_2 PF07719.17 CBZ23398.1 - 3.3e-20 70.5 19.3 0.00059 19.8 0.1 10.0 10 0 0 10 10 9 4 Tetratricopeptide repeat TPR_1 PF00515.28 CBZ23398.1 - 1.2e-14 53.4 8.3 0.025 14.4 0.1 8.8 9 0 0 9 9 9 3 Tetratricopeptide repeat TPR_14 PF13428.6 CBZ23398.1 - 6.3e-14 51.5 36.9 5.4e-05 23.7 0.2 10.8 6 1 5 11 11 11 4 Tetratricopeptide repeat TPR_12 PF13424.6 CBZ23398.1 - 2.2e-11 43.9 29.4 8.8e-05 22.7 0.4 8.9 8 1 2 10 10 10 3 Tetratricopeptide repeat TPR_19 PF14559.6 CBZ23398.1 - 1e-10 41.9 30.4 1.8e-06 28.4 0.3 8.3 4 2 2 7 7 7 1 Tetratricopeptide repeat TPR_16 PF13432.6 CBZ23398.1 - 1.8e-10 41.3 49.4 0.013 16.2 0.4 8.5 9 0 0 9 9 9 5 Tetratricopeptide repeat TPR_17 PF13431.6 CBZ23398.1 - 3.7e-08 33.2 4.5 0.00032 20.9 0.0 6.1 7 1 0 7 7 4 1 Tetratricopeptide repeat ANAPC3 PF12895.7 CBZ23398.1 - 4.2e-08 33.3 25.0 0.0051 17.0 0.3 5.6 5 0 0 5 5 5 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_11 PF13414.6 CBZ23398.1 - 7.5e-07 28.7 3.1 0.48 10.1 0.0 5.9 4 1 1 5 5 5 1 TPR repeat TPR_9 PF13371.6 CBZ23398.1 - 1.9e-05 24.7 1.1 1.9e-05 24.7 1.1 6.2 4 1 2 6 6 6 1 Tetratricopeptide repeat TPR_6 PF13174.6 CBZ23398.1 - 0.00034 21.1 21.8 1.3 9.8 0.2 9.0 9 0 0 9 9 8 1 Tetratricopeptide repeat BTAD PF03704.17 CBZ23398.1 - 0.00062 20.2 3.4 0.00062 20.2 3.4 4.5 3 1 0 4 4 4 1 Bacterial transcriptional activator domain TPR_8 PF13181.6 CBZ23398.1 - 0.0022 18.1 5.8 2.2 8.7 0.0 5.5 7 0 0 7 7 5 1 Tetratricopeptide repeat NARP1 PF12569.8 CBZ23398.1 - 0.0065 15.4 1.1 0.47 9.3 0.0 2.3 1 1 1 2 2 2 1 NMDA receptor-regulated protein 1 TPR_15 PF13429.6 CBZ23398.1 - 0.011 15.0 0.2 0.011 15.0 0.2 3.9 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_7 PF13176.6 CBZ23398.1 - 0.012 15.6 5.2 23 5.3 0.0 5.8 4 1 2 6 6 6 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 CBZ23398.1 - 0.11 12.6 7.6 0.17 12.0 0.1 4.3 4 0 0 4 4 4 0 Fis1 C-terminal tetratricopeptide repeat Tctex-1 PF03645.13 CBZ23399.1 - 2.3e-24 85.6 0.8 2.6e-24 85.4 0.8 1.0 1 0 0 1 1 1 1 Tctex-1 family Metallophos PF00149.28 CBZ23400.1 - 0.0022 18.6 0.0 0.035 14.6 0.0 2.6 2 1 0 2 2 2 1 Calcineurin-like phosphoesterase NGP1NT PF08153.12 CBZ23403.1 - 2.8e-44 150.4 0.7 2.8e-44 150.4 0.7 1.8 2 0 0 2 2 2 1 NGP1NT (NUC091) domain MMR_HSR1 PF01926.23 CBZ23403.1 - 9.7e-19 67.5 0.3 6.4e-15 55.2 0.0 2.9 2 1 0 2 2 2 2 50S ribosome-binding GTPase FeoB_N PF02421.18 CBZ23403.1 - 1.5e-05 24.6 0.1 9.9e-05 21.9 0.1 2.1 2 0 0 2 2 2 1 Ferrous iron transport protein B GTP_EFTU PF00009.27 CBZ23403.1 - 0.001 18.6 0.3 0.32 10.5 0.0 3.6 4 0 0 4 4 4 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 CBZ23403.1 - 0.0012 18.8 0.0 0.025 14.5 0.0 2.4 1 1 0 1 1 1 1 RsgA GTPase Dynamin_N PF00350.23 CBZ23403.1 - 0.1 12.7 13.8 0.76 9.8 0.0 4.8 3 3 1 4 4 4 0 Dynamin family Roc PF08477.13 CBZ23403.1 - 0.1 12.8 0.1 9.2 6.5 0.0 2.7 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_16 PF13191.6 CBZ23403.1 - 0.1 13.0 0.0 0.1 13.0 0.0 2.7 3 1 0 3 3 3 0 AAA ATPase domain AAA_18 PF13238.6 CBZ23403.1 - 0.72 10.4 0.0 0.72 10.4 0.0 2.8 2 1 0 2 2 2 0 AAA domain MFS_1 PF07690.16 CBZ23405.1 - 9e-25 87.3 44.6 1e-18 67.4 11.1 2.2 1 1 0 2 2 2 2 Major Facilitator Superfamily ATP-synt_G PF04718.15 CBZ23406.1 - 0.033 15.0 0.0 0.049 14.5 0.0 1.4 1 0 0 1 1 1 0 Mitochondrial ATP synthase g subunit ATP-synt_ab PF00006.25 CBZ23407.1 - 3.2e-67 226.3 0.1 4.9e-67 225.7 0.1 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.27 CBZ23407.1 - 1.2e-08 35.3 0.8 8.3e-08 32.6 0.0 2.2 2 0 0 2 2 2 1 ATP synthase alpha/beta chain, C terminal domain His_kinase PF06580.13 CBZ23407.1 - 0.92 9.9 4.3 0.93 9.9 0.3 2.4 1 1 1 2 2 2 0 Histidine kinase ATP-synt_ab PF00006.25 CBZ23408.1 - 4.4e-67 225.9 0.1 6.8e-67 225.2 0.1 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.27 CBZ23408.1 - 1.8e-08 34.7 0.8 1e-07 32.3 0.0 2.1 2 0 0 2 2 2 1 ATP synthase alpha/beta chain, C terminal domain His_kinase PF06580.13 CBZ23408.1 - 0.93 9.9 3.8 1.1 9.6 0.2 2.4 1 1 1 2 2 2 0 Histidine kinase ADH_zinc_N PF00107.26 CBZ23409.1 - 1.4e-06 28.3 0.2 2.6e-06 27.5 0.2 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 CBZ23409.1 - 0.019 14.8 0.1 0.045 13.6 0.1 1.7 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-like domain ATXN-1_C PF12547.8 CBZ23410.1 - 0.29 11.5 0.1 0.29 11.5 0.1 5.0 4 0 0 4 4 4 0 Capicua transcriptional repressor modulator LSM PF01423.22 CBZ23411.1 - 2.4e-05 23.9 0.5 0.00043 19.9 0.5 2.3 1 1 0 1 1 1 1 LSM domain Pkinase PF00069.25 CBZ23412.1 - 9.1e-68 228.5 0.0 1e-67 228.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ23412.1 - 1.5e-31 109.7 0.0 2e-31 109.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 CBZ23412.1 - 0.00055 19.3 0.1 0.00091 18.6 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 CBZ23412.1 - 0.0029 17.6 0.0 0.036 14.0 0.0 2.2 1 1 1 2 2 2 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 CBZ23412.1 - 0.019 13.9 0.0 0.027 13.4 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain Pkinase_fungal PF17667.1 CBZ23412.1 - 0.036 12.9 0.0 0.091 11.5 0.0 1.5 1 1 1 2 2 2 0 Fungal protein kinase Motile_Sperm PF00635.26 CBZ23413.1 - 0.0012 18.7 0.0 0.0076 16.1 0.0 2.1 2 0 0 2 2 2 1 MSP (Major sperm protein) domain NDUF_B5 PF09781.9 CBZ23414.1 - 0.07 12.7 1.1 0.13 11.8 1.1 1.4 1 0 0 1 1 1 0 NADH:ubiquinone oxidoreductase, NDUFB5/SGDH subunit DUF2106 PF09879.9 CBZ23415.1 - 0.12 11.9 0.0 0.5 9.9 0.0 2.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2106) DEAD PF00270.29 CBZ23416.1 - 2.5e-32 112.1 0.1 5.6e-17 62.1 0.0 2.4 2 0 0 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.31 CBZ23416.1 - 3.1e-21 75.8 0.1 2.7e-20 72.8 0.1 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 CBZ23416.1 - 2e-05 24.7 0.0 6.4e-05 23.0 0.0 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 CBZ23416.1 - 0.14 12.4 0.1 3.3 8.0 0.0 2.8 2 0 0 2 2 2 0 AAA domain DUF4611 PF15387.6 CBZ23416.1 - 0.15 12.3 2.9 0.58 10.4 2.9 2.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) CDC45 PF02724.14 CBZ23416.1 - 0.21 9.8 0.8 0.84 7.9 0.9 1.7 2 0 0 2 2 2 0 CDC45-like protein PBP1_TM PF14812.6 CBZ23416.1 - 0.48 10.8 11.0 0.064 13.6 6.0 2.1 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal CbiG_C PF01890.16 CBZ23416.1 - 0.49 11.0 5.6 0.28 11.8 2.6 2.1 2 0 0 2 2 2 0 Cobalamin synthesis G C-terminus RPN2_C PF18004.1 CBZ23416.1 - 4.5 7.2 5.8 4.2 7.3 0.9 2.3 2 0 0 2 2 2 0 26S proteasome regulatory subunit RPN2 C-terminal domain COG4 PF08318.12 CBZ23417.1 - 9e-45 153.2 1.4 9e-45 153.2 1.4 2.0 2 2 0 2 2 2 1 COG4 transport protein RINT1_TIP1 PF04437.13 CBZ23417.1 - 0.014 14.3 0.4 0.072 12.0 0.0 2.0 2 0 0 2 2 2 0 RINT-1 / TIP-1 family TPK_catalytic PF04263.16 CBZ23417.1 - 0.27 11.3 1.2 3.3 7.8 0.0 2.9 4 0 0 4 4 4 0 Thiamin pyrophosphokinase, catalytic domain Surp PF01805.20 CBZ23418.1 - 5.4e-10 39.1 0.0 9.8e-10 38.3 0.0 1.4 1 0 0 1 1 1 1 Surp module ubiquitin PF00240.23 CBZ23419.1 - 0.13 12.0 0.0 0.24 11.2 0.0 1.3 1 0 0 1 1 1 0 Ubiquitin family Kinesin PF00225.23 CBZ23420.1 - 1.1e-86 290.8 0.0 1.8e-86 290.1 0.0 1.3 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 CBZ23420.1 - 2.8e-21 76.0 0.0 4.9e-18 65.5 0.0 2.7 2 0 0 2 2 2 2 Microtubule binding SUIM_assoc PF16619.5 CBZ23420.1 - 1.3 9.1 7.1 16 5.7 0.0 3.1 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 SesA PF17107.5 CBZ23420.1 - 2.6 8.3 5.5 5.7 7.2 1.3 2.9 2 0 0 2 2 2 0 N-terminal domain on NACHT_NTPase and P-loop NTPases Ank_2 PF12796.7 CBZ23421.1 - 4.5e-43 145.7 13.2 2.5e-10 40.8 0.0 11.6 11 2 3 14 14 14 9 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CBZ23421.1 - 4e-29 100.6 19.7 3.1e-05 24.4 0.3 13.8 13 2 2 15 15 15 7 Ankyrin repeats (many copies) Ank_3 PF13606.6 CBZ23421.1 - 3.1e-23 79.3 22.7 0.0089 16.5 0.0 16.7 18 0 0 18 18 18 5 Ankyrin repeat Ank_5 PF13857.6 CBZ23421.1 - 1.2e-19 70.1 22.3 0.00022 21.4 0.0 11.5 12 1 1 13 13 13 4 Ankyrin repeats (many copies) Ank PF00023.30 CBZ23421.1 - 2.6e-18 65.6 30.7 0.00021 21.6 0.0 15.5 17 0 0 17 17 17 5 Ankyrin repeat LRR_4 PF12799.7 CBZ23422.1 - 0.0013 19.1 0.8 0.0045 17.4 0.4 2.0 2 0 0 2 2 2 1 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 CBZ23422.1 - 0.019 15.0 3.8 4.2 7.7 0.0 4.4 4 0 0 4 4 4 0 Leucine Rich repeat LRR_8 PF13855.6 CBZ23422.1 - 0.019 14.7 1.2 0.1 12.4 1.2 2.2 2 1 0 2 2 2 0 Leucine rich repeat Nitroreductase PF00881.24 CBZ23423.1 - 1e-33 116.8 0.0 1.3e-33 116.4 0.0 1.2 1 0 0 1 1 1 1 Nitroreductase family TM1586_NiRdase PF14512.6 CBZ23423.1 - 0.015 14.9 0.1 4.9 6.6 0.0 2.5 2 1 0 2 2 2 0 Putative TM nitroreductase DUF1560 PF07597.11 CBZ23423.1 - 0.081 13.0 0.0 0.26 11.3 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1560) Mtc PF03820.17 CBZ23425.1 - 7.9e-93 310.9 0.7 9.6e-93 310.6 0.7 1.0 1 0 0 1 1 1 1 Tricarboxylate carrier SHIPPO-rpt PF07004.12 CBZ23426.1 - 7.9e-55 181.4 169.4 0.0077 17.1 0.1 37.3 38 0 0 38 38 38 28 Sperm-tail PG-rich repeat EKLF_TAD1 PF16832.5 CBZ23426.1 - 1.2 9.1 7.6 17 5.4 0.2 4.2 2 0 0 2 2 2 0 Erythroid krueppel-like transcription factor, transactivation 1 Cyclin PF08613.11 CBZ23428.1 - 2.2e-18 67.1 0.0 2.2e-18 67.1 0.0 3.5 3 2 0 3 3 3 1 Cyclin Cyclin_N PF00134.23 CBZ23428.1 - 0.002 17.9 0.0 0.0048 16.6 0.0 1.6 1 0 0 1 1 1 1 Cyclin, N-terminal domain DSPc PF00782.20 CBZ23429.1 - 3e-19 69.2 0.0 3.9e-07 30.0 0.0 3.3 3 0 0 3 3 3 3 Dual specificity phosphatase, catalytic domain Vta1 PF04652.16 CBZ23431.1 - 1.2e-33 116.1 0.3 2e-33 115.4 0.3 1.3 1 0 0 1 1 1 1 Vta1 like Vta1_C PF18097.1 CBZ23431.1 - 2.1e-13 49.7 2.1 2.1e-13 49.7 2.1 1.9 2 0 0 2 2 2 1 Vta1 C-terminal domain SOG2 PF10428.9 CBZ23431.1 - 7.6 5.6 13.4 9.7 5.3 13.4 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein Wyosine_form PF08608.12 CBZ23432.1 - 9.9e-19 67.5 1.4 7.5e-17 61.5 1.4 2.6 1 1 0 1 1 1 1 Wyosine base formation Radical_SAM PF04055.21 CBZ23432.1 - 1.4e-18 67.9 0.0 2.6e-18 66.9 0.0 1.5 1 0 0 1 1 1 1 Radical SAM superfamily Flavodoxin_1 PF00258.25 CBZ23432.1 - 3.4e-12 46.8 0.1 2.1e-10 41.0 0.0 2.4 1 1 1 2 2 2 1 Flavodoxin FEZ PF07763.13 CBZ23432.1 - 0.2 11.4 0.0 0.34 10.6 0.0 1.3 1 0 0 1 1 1 0 FEZ-like protein Kinesin PF00225.23 CBZ23433.1 - 2.5e-80 269.9 0.0 6.9e-53 179.7 0.4 2.2 2 0 0 2 2 2 2 Kinesin motor domain Microtub_bd PF16796.5 CBZ23433.1 - 3.2e-11 43.4 0.0 1.5e-09 37.9 0.0 2.4 2 0 0 2 2 2 1 Microtubule binding MAM33 PF02330.16 CBZ23436.1 - 2.4e-14 53.8 0.0 5.7e-14 52.6 0.0 1.7 2 0 0 2 2 2 1 Mitochondrial glycoprotein zf-MYND PF01753.18 CBZ23437.1 - 1e-10 41.5 12.1 1e-10 41.5 12.1 2.0 2 0 0 2 2 2 1 MYND finger RNA_pol_Rpc4 PF05132.14 CBZ23437.1 - 0.16 12.4 0.0 0.3 11.5 0.0 1.4 1 0 0 1 1 1 0 RNA polymerase III RPC4 Neurokinin_B PF03823.14 CBZ23437.1 - 0.98 9.5 4.6 5.7 7.1 0.3 3.2 3 0 0 3 3 3 0 Neurokinin B Got1 PF04178.12 CBZ23438.1 - 6.4e-31 107.1 13.9 8e-31 106.8 13.9 1.1 1 0 0 1 1 1 1 Got1/Sft2-like family 7tm_3 PF00003.22 CBZ23438.1 - 0.11 12.1 13.3 0.017 14.8 8.8 1.6 1 1 0 1 1 1 0 7 transmembrane sweet-taste receptor of 3 GCPR Bac_export_2 PF01312.19 CBZ23438.1 - 0.13 11.4 0.6 0.14 11.3 0.6 1.1 1 0 0 1 1 1 0 FlhB HrpN YscU SpaS Family DUF4064 PF13273.6 CBZ23438.1 - 1.2 9.5 9.0 5.8 7.3 8.7 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF4064) YwiC PF14256.6 CBZ23438.1 - 1.3 9.4 9.5 1.8 8.9 9.5 1.2 1 0 0 1 1 1 0 YwiC-like protein DUF4191 PF13829.6 CBZ23438.1 - 5.6 6.2 5.8 3.4 6.9 1.9 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4191) DUF2721 PF11026.8 CBZ23438.1 - 7.2 6.5 12.0 12 5.8 3.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2721) DUF1841 PF08897.11 CBZ23439.1 - 0.14 12.2 0.3 0.35 10.9 0.3 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1841) PNP_UDP_1 PF01048.20 CBZ23440.1 - 7.5e-36 123.6 0.3 9.4e-36 123.2 0.3 1.1 1 0 0 1 1 1 1 Phosphorylase superfamily zf-C2HC_2 PF13913.6 CBZ23442.1 - 3.8e-14 52.2 9.3 1.5e-08 34.3 2.2 2.4 2 0 0 2 2 2 2 zinc-finger of a C2HC-type zf-CpG_bind_C PF12269.8 CBZ23442.1 - 0.0024 17.7 0.2 1.6 8.4 0.0 2.3 2 0 0 2 2 2 2 CpG binding protein zinc finger C terminal domain zf-C2H2_4 PF13894.6 CBZ23442.1 - 0.15 13.0 0.8 2.8 9.0 0.1 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2 PF00096.26 CBZ23442.1 - 0.17 12.4 0.7 6.5 7.4 0.1 2.5 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-C2H2_11 PF16622.5 CBZ23442.1 - 0.22 11.3 0.3 9 6.2 0.0 2.4 2 0 0 2 2 2 0 zinc-finger C2H2-type Cys_rich_CPXG PF14255.6 CBZ23442.1 - 0.22 11.5 0.8 12 5.9 0.1 2.3 2 0 0 2 2 2 0 Cysteine-rich CPXCG Hamartin PF04388.12 CBZ23442.1 - 2.9 6.4 4.6 4.7 5.8 4.6 1.3 1 0 0 1 1 1 0 Hamartin protein zf-FPG_IleRS PF06827.14 CBZ23442.1 - 3.9 7.4 6.5 4.4 7.3 0.2 2.5 2 0 0 2 2 2 0 Zinc finger found in FPG and IleRS MMS1_N PF10433.9 CBZ23446.1 - 1.4e-34 119.6 0.0 1.9e-19 69.7 0.0 4.3 3 1 0 3 3 3 3 Mono-functional DNA-alkylating methyl methanesulfonate N-term CPSF_A PF03178.15 CBZ23446.1 - 9.8e-16 58.0 0.0 1.5e-10 40.9 0.0 3.3 3 0 0 3 3 3 2 CPSF A subunit region YL1 PF05764.13 CBZ23446.1 - 0.054 13.6 1.1 0.13 12.4 1.1 1.5 1 0 0 1 1 1 0 YL1 nuclear protein DUF4228 PF14009.6 CBZ23446.1 - 1.9 8.8 5.2 0.78 10.1 0.1 3.0 3 1 0 3 3 3 0 Domain of unknown function (DUF4228) CENP-B_dimeris PF09026.10 CBZ23446.1 - 4.7 7.7 10.4 11 6.5 10.4 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain LRR_8 PF13855.6 CBZ23447.1 - 8.6e-07 28.6 0.5 1.8e-05 24.4 0.3 2.2 2 0 0 2 2 2 1 Leucine rich repeat LRR_4 PF12799.7 CBZ23447.1 - 0.0015 18.9 3.8 0.015 15.7 0.7 2.5 1 1 1 2 2 2 2 Leucine Rich repeats (2 copies) LRRNT_2 PF08263.12 CBZ23448.1 - 0.12 12.7 0.9 0.26 11.6 0.9 1.5 1 0 0 1 1 1 0 Leucine rich repeat N-terminal domain Flagellar_rod PF05149.12 CBZ23449.1 - 1.7e-93 313.3 31.0 1.7e-93 313.3 31.0 2.2 3 0 0 3 3 3 1 Paraflagellar rod protein UQ_con PF00179.26 CBZ23450.1 - 2.5e-10 40.2 0.0 4.4e-10 39.4 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Peptidase_C98 PF15499.6 CBZ23450.1 - 0.12 11.8 0.1 0.19 11.2 0.1 1.2 1 0 0 1 1 1 0 Ubiquitin-specific peptidase-like, SUMO isopeptidase Peptidase_M28 PF04389.17 CBZ23452.1 - 2e-18 66.8 0.6 3.9e-06 26.7 0.0 3.7 4 0 0 4 4 4 3 Peptidase family M28 Peptidase_M49 PF03571.15 CBZ23453.1 - 1.1e-221 737.0 0.0 1.4e-221 736.7 0.0 1.0 1 0 0 1 1 1 1 Peptidase family M49 SinI PF08671.10 CBZ23453.1 - 0.18 11.6 0.0 0.46 10.3 0.0 1.7 1 0 0 1 1 1 0 Anti-repressor SinI DUF1930 PF09122.10 CBZ23454.1 - 2.4e-36 123.6 0.1 4.4e-36 122.7 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1930) Rhodanese PF00581.20 CBZ23454.1 - 9.3e-14 51.8 0.0 2.2e-07 31.4 0.0 2.3 2 0 0 2 2 2 2 Rhodanese-like domain Complex1_51K PF01512.17 CBZ23455.1 - 1.2e-45 155.1 0.0 2.3e-45 154.2 0.0 1.4 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase 51 Kd subunit NADH_4Fe-4S PF10589.9 CBZ23455.1 - 5e-29 100.2 0.0 1.3e-28 98.9 0.0 1.7 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region SLBB PF10531.9 CBZ23455.1 - 5e-08 32.7 0.0 9e-08 31.9 0.0 1.4 1 0 0 1 1 1 1 SLBB domain Ribosomal_S26e PF01283.19 CBZ23455.1 - 0.15 12.5 0.1 0.72 10.3 0.0 1.9 2 0 0 2 2 2 0 Ribosomal protein S26e NDUF_B7 PF05676.13 CBZ23456.1 - 0.056 13.2 0.3 0.076 12.8 0.3 1.2 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) zf-C3HC4_3 PF13920.6 CBZ23457.1 - 0.00028 20.7 7.1 0.00047 20.0 7.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C2HC5 PF06221.13 CBZ23457.1 - 0.00055 19.9 3.8 0.00055 19.9 3.8 1.6 2 0 0 2 2 2 1 Putative zinc finger motif, C2HC5-type zf-RING_5 PF14634.6 CBZ23457.1 - 0.0057 16.6 7.3 0.01 15.8 7.3 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.6 CBZ23457.1 - 0.24 11.8 8.3 0.4 11.1 8.3 1.4 1 0 0 1 1 1 0 Ring finger domain TerY_C PF15616.6 CBZ23457.1 - 6.7 6.8 8.6 8.5 6.5 8.3 1.3 1 1 0 1 1 1 0 TerY-C metal binding domain UPF0020 PF01170.18 CBZ23458.1 - 3.8e-12 46.3 0.0 1.2e-11 44.6 0.0 1.8 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 N6_Mtase PF02384.16 CBZ23458.1 - 0.0022 17.3 0.0 0.013 14.8 0.0 2.1 3 0 0 3 3 3 1 N-6 DNA Methylase N6_N4_Mtase PF01555.18 CBZ23458.1 - 0.0056 16.4 0.0 0.045 13.4 0.0 2.1 2 0 0 2 2 2 1 DNA methylase Methyltransf_25 PF13649.6 CBZ23458.1 - 0.16 12.7 0.0 0.39 11.4 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain PsiA PF06952.11 CBZ23459.1 - 0.041 13.1 1.3 0.083 12.1 1.3 1.4 1 0 0 1 1 1 0 PsiA protein Band_7 PF01145.25 CBZ23461.1 - 1.9e-25 89.9 0.9 2.8e-25 89.4 0.1 1.6 2 0 0 2 2 2 1 SPFH domain / Band 7 family Band_7_C PF16200.5 CBZ23461.1 - 9.5e-22 76.8 1.6 1.4e-21 76.3 0.6 1.8 2 0 0 2 2 2 1 C-terminal region of band_7 Band_7_1 PF13421.6 CBZ23461.1 - 0.015 15.0 0.1 0.029 14.1 0.1 1.5 1 0 0 1 1 1 0 SPFH domain-Band 7 family Lipoprotein_16 PF03923.13 CBZ23462.1 - 0.041 13.5 0.5 0.081 12.6 0.5 1.4 1 0 0 1 1 1 0 Uncharacterized lipoprotein DUF3498 PF12004.8 CBZ23462.1 - 7.2 5.7 11.8 15 4.6 11.8 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF3498) AFG1_ATPase PF03969.16 CBZ23463.1 - 2.5e-82 276.6 0.1 3.1e-75 253.3 0.0 3.0 2 1 1 3 3 3 3 AFG1-like ATPase AAA_22 PF13401.6 CBZ23463.1 - 0.0041 17.4 0.0 0.0076 16.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain Bac_DnaA PF00308.18 CBZ23463.1 - 0.044 13.6 0.0 0.35 10.7 0.0 2.3 3 0 0 3 3 3 0 Bacterial dnaA protein ABC_tran PF00005.27 CBZ23463.1 - 0.079 13.5 0.0 0.18 12.4 0.0 1.6 1 0 0 1 1 1 0 ABC transporter AFG1_ATPase PF03969.16 CBZ23464.1 - 2e-62 211.2 0.1 5.7e-57 193.3 0.0 2.0 1 1 1 2 2 2 2 AFG1-like ATPase Lectin_leg-like PF03388.13 CBZ23465.1 - 4.5e-11 42.5 0.0 9e-06 25.2 0.0 3.2 2 1 0 2 2 2 2 Legume-like lectin family YL1 PF05764.13 CBZ23465.1 - 0.00051 20.2 0.6 0.00073 19.7 0.6 1.3 1 0 0 1 1 1 1 YL1 nuclear protein MORN PF02493.20 CBZ23466.1 - 1.2e-25 87.8 32.8 9e-08 31.6 1.8 7.2 7 0 0 7 7 7 5 MORN repeat Myc_N PF01056.18 CBZ23466.1 - 4.4 7.1 7.4 16 5.3 2.9 2.3 2 0 0 2 2 2 0 Myc amino-terminal region Rad21_Rec8_N PF04825.13 CBZ23467.1 - 1.8e-28 98.9 0.1 3.7e-28 97.9 0.1 1.5 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.16 CBZ23467.1 - 4.5e-08 32.3 0.4 6.6e-07 28.5 0.0 2.6 2 0 0 2 2 2 1 Conserved region of Rad21 / Rec8 like protein SMC_ScpA PF02616.14 CBZ23467.1 - 0.089 12.7 0.1 17 5.2 0.0 2.2 2 0 0 2 2 2 0 Segregation and condensation protein ScpA Methyltransf_31 PF13847.6 CBZ23468.1 - 1.5e-10 41.1 0.0 1.8e-10 40.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CBZ23468.1 - 7.6e-09 36.2 0.0 3.5e-08 34.0 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CBZ23468.1 - 7.7e-09 36.1 0.0 3e-08 34.2 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CBZ23468.1 - 5.8e-07 30.2 0.0 1e-06 29.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.15 CBZ23468.1 - 1.4e-05 25.1 0.0 0.15 11.9 0.0 2.1 2 0 0 2 2 2 2 Hypothetical methyltransferase NodS PF05401.11 CBZ23468.1 - 1.8e-05 24.5 0.0 3.2e-05 23.6 0.0 1.4 1 1 0 1 1 1 1 Nodulation protein S (NodS) TPMT PF05724.11 CBZ23468.1 - 3.1e-05 23.8 0.0 0.00075 19.2 0.0 2.2 2 0 0 2 2 2 1 Thiopurine S-methyltransferase (TPMT) Ubie_methyltran PF01209.18 CBZ23468.1 - 0.0028 17.0 0.0 0.0093 15.3 0.0 1.7 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_32 PF13679.6 CBZ23468.1 - 0.0061 16.6 0.0 0.0095 15.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Pox_MCEL PF03291.16 CBZ23468.1 - 0.0093 15.1 0.0 0.03 13.4 0.0 1.7 1 1 0 1 1 1 1 mRNA capping enzyme MTS PF05175.14 CBZ23468.1 - 0.01 15.4 0.0 0.038 13.5 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase small domain CMAS PF02353.20 CBZ23468.1 - 0.024 13.9 0.0 0.036 13.3 0.0 1.3 1 1 0 1 1 1 0 Mycolic acid cyclopropane synthetase EutQ PF06249.12 CBZ23468.1 - 0.047 13.4 0.0 0.088 12.6 0.0 1.4 1 0 0 1 1 1 0 Ethanolamine utilisation protein EutQ Spermine_synth PF01564.17 CBZ23468.1 - 0.094 12.1 0.0 0.19 11.1 0.0 1.4 1 1 0 1 1 1 0 Spermine/spermidine synthase domain RRM_1 PF00076.22 CBZ23469.1 - 3.3e-09 36.4 0.0 0.0074 16.1 0.0 4.3 4 0 0 4 4 4 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) vATP-synt_AC39 PF01992.16 CBZ23472.1 - 2e-86 290.6 0.4 2.2e-86 290.4 0.4 1.0 1 0 0 1 1 1 1 ATP synthase (C/AC39) subunit LRR_4 PF12799.7 CBZ23473.1 - 1.7e-10 40.9 6.3 0.0017 18.7 0.0 5.9 6 0 0 6 6 6 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CBZ23473.1 - 5e-07 29.4 4.9 0.68 9.7 0.0 5.8 6 0 0 6 6 6 2 Leucine rich repeat LRR_6 PF13516.6 CBZ23473.1 - 0.00089 19.1 15.1 2.4 8.4 0.1 6.1 6 0 0 6 6 6 2 Leucine Rich repeat LRR_1 PF00560.33 CBZ23473.1 - 0.00099 19.3 11.2 12 6.9 0.0 6.0 6 0 0 6 6 6 1 Leucine Rich Repeat PEHE PF15275.6 CBZ23473.1 - 0.083 13.5 2.3 0.28 11.8 2.3 1.9 1 0 0 1 1 1 0 PEHE domain FAM76 PF16046.5 CBZ23473.1 - 0.43 9.9 1.3 0.64 9.3 1.3 1.1 1 0 0 1 1 1 0 FAM76 protein ERM PF00769.19 CBZ23473.1 - 0.77 9.5 14.4 1.4 8.6 14.4 1.3 1 0 0 1 1 1 0 Ezrin/radixin/moesin family HAUS-augmin3 PF14932.6 CBZ23473.1 - 1 8.9 10.2 3.1 7.3 7.4 2.3 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 3 Spc7 PF08317.11 CBZ23473.1 - 1.1 8.1 8.0 1.7 7.5 8.0 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein ADIP PF11559.8 CBZ23473.1 - 1.1 9.3 11.1 2.2 8.4 11.1 1.4 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding CorA PF01544.18 CBZ23473.1 - 3.3 7.0 8.0 5.3 6.3 8.0 1.2 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein ELO PF01151.18 CBZ23474.1 - 1.3e-42 146.1 28.7 2e-42 145.5 28.7 1.3 1 1 0 1 1 1 1 GNS1/SUR4 family NDUFA12 PF05071.16 CBZ23475.1 - 0.012 16.4 0.2 0.054 14.3 0.2 2.1 1 0 0 1 1 1 0 NADH ubiquinone oxidoreductase subunit NDUFA12 DUF346 PF03984.13 CBZ23475.1 - 0.035 13.9 5.4 0.18 11.6 2.9 2.6 2 0 0 2 2 2 0 Repeat of unknown function (DUF346) V_ATPase_I PF01496.19 CBZ23476.1 - 8.4 4.2 5.6 8.6 4.1 1.8 2.4 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family Prefoldin_2 PF01920.20 CBZ23477.1 - 3.2e-18 65.6 4.2 3.2e-18 65.6 4.2 1.5 1 1 0 1 1 1 1 Prefoldin subunit DHR10 PF18595.1 CBZ23477.1 - 0.017 15.2 10.6 0.023 14.7 0.3 2.2 2 0 0 2 2 2 0 Designed helical repeat protein 10 domain ApoLp-III PF07464.11 CBZ23477.1 - 0.038 14.1 3.0 0.36 10.9 1.2 2.2 2 0 0 2 2 2 0 Apolipophorin-III precursor (apoLp-III) kleA_kleC PF17383.2 CBZ23477.1 - 0.06 13.7 1.2 0.13 12.6 1.2 1.5 1 0 0 1 1 1 0 Uncharacterized KorC regulated protein A PCRF PF03462.18 CBZ23477.1 - 0.15 11.9 3.9 0.22 11.4 0.0 2.0 1 1 1 2 2 2 0 PCRF domain Spc7 PF08317.11 CBZ23477.1 - 0.21 10.5 9.1 0.79 8.5 2.8 2.0 2 0 0 2 2 2 0 Spc7 kinetochore protein FlaC_arch PF05377.11 CBZ23477.1 - 0.26 11.7 3.3 9.8 6.7 0.3 2.8 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) DASH_Spc19 PF08287.11 CBZ23477.1 - 0.48 10.3 9.6 0.23 11.3 2.4 2.1 1 1 1 2 2 2 0 Spc19 Spc24 PF08286.11 CBZ23477.1 - 0.98 9.7 7.9 5.2 7.4 2.6 2.1 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 Osmo_CC PF08946.10 CBZ23477.1 - 5.9 7.2 13.7 35 4.8 7.8 3.6 2 2 0 2 2 2 0 Osmosensory transporter coiled coil OmpH PF03938.14 CBZ23477.1 - 9.6 6.5 15.3 96 3.3 15.3 2.1 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) LRR_4 PF12799.7 CBZ23478.1 - 1.1e-24 86.1 25.2 6.9e-05 23.1 0.1 7.3 3 3 4 7 7 7 6 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CBZ23478.1 - 5.4e-23 80.5 36.5 2.8e-08 33.4 5.2 6.4 2 2 5 7 7 7 6 Leucine rich repeat LRR_9 PF14580.6 CBZ23478.1 - 3.2e-20 72.3 2.7 2.8e-08 33.5 0.1 3.2 3 0 0 3 3 3 3 Leucine-rich repeat LRR_6 PF13516.6 CBZ23478.1 - 1.8e-05 24.4 16.2 0.97 9.7 0.0 8.6 10 0 0 10 10 10 3 Leucine Rich repeat LRR_1 PF00560.33 CBZ23478.1 - 0.057 14.0 21.9 16 6.5 0.1 8.9 9 1 0 9 9 9 0 Leucine Rich Repeat Chlorovi_GP_rpt PF06598.11 CBZ23479.1 - 0.014 15.4 1.6 3.4 7.8 0.0 3.1 3 0 0 3 3 3 0 Chlorovirus glycoprotein repeat LRR_4 PF12799.7 CBZ23479.1 - 0.067 13.6 0.0 13 6.4 0.0 2.9 3 0 0 3 3 3 0 Leucine Rich repeats (2 copies) CENP-T_C PF15511.6 CBZ23480.1 - 2.2e-06 27.8 0.1 3.2e-06 27.2 0.1 1.3 1 1 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold TAF PF02969.17 CBZ23480.1 - 0.00022 21.3 0.1 0.00037 20.6 0.1 1.3 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.23 CBZ23480.1 - 0.00058 20.1 0.9 0.00064 20.0 0.1 1.4 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.13 CBZ23480.1 - 0.0011 18.9 0.0 0.0015 18.5 0.0 1.1 1 0 0 1 1 1 1 Bromodomain associated Histone PF00125.24 CBZ23480.1 - 0.0013 19.1 2.7 0.0025 18.2 2.7 1.6 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID-31kDa PF02291.15 CBZ23480.1 - 0.0075 16.3 0.0 0.0098 16.0 0.0 1.1 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit Ribosomal_S17e PF00833.18 CBZ23480.1 - 0.041 13.8 0.5 0.05 13.5 0.5 1.1 1 0 0 1 1 1 0 Ribosomal S17 PCP_red PF08369.10 CBZ23480.1 - 0.15 12.3 1.8 0.4 10.9 0.2 2.3 2 1 0 2 2 2 0 Proto-chlorophyllide reductase 57 kD subunit LRR_4 PF12799.7 CBZ23481.1 - 1.6e-16 60.1 4.5 0.12 12.8 0.1 8.9 5 2 6 11 11 11 7 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CBZ23481.1 - 0.00071 19.3 11.4 6.5 6.6 0.2 6.7 4 2 4 8 8 8 3 Leucine rich repeat LRR_6 PF13516.6 CBZ23481.1 - 0.001 18.9 19.6 3.5 7.9 0.2 10.0 13 0 0 13 13 13 3 Leucine Rich repeat WD40 PF00400.32 CBZ23482.1 - 8.7e-51 168.8 25.3 4.2e-08 33.7 0.0 7.4 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBZ23482.1 - 3.6e-07 30.4 0.7 0.0016 18.7 0.1 4.1 1 1 4 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 CBZ23482.1 - 7.6e-05 22.2 0.3 0.22 10.8 0.1 3.2 3 1 0 3 3 3 2 WD40-like domain Nup160 PF11715.8 CBZ23482.1 - 0.0083 14.8 11.7 0.073 11.7 0.4 4.6 1 1 3 5 5 5 3 Nucleoporin Nup120/160 PB1 PF00564.24 CBZ23482.1 - 0.009 15.9 0.0 0.034 14.1 0.1 2.0 2 0 0 2 2 2 1 PB1 domain MRP-L46 PF11788.8 CBZ23483.1 - 1.6e-15 57.9 0.0 4.1e-15 56.6 0.0 1.7 1 1 0 1 1 1 1 39S mitochondrial ribosomal protein L46 PUF PF00806.19 CBZ23484.1 - 1.9e-23 80.8 6.6 2.6e-05 23.7 0.0 6.1 6 0 0 6 6 6 5 Pumilio-family RNA binding repeat DUF832 PF05734.11 CBZ23484.1 - 0.033 13.7 0.6 0.14 11.6 0.2 1.9 1 1 1 2 2 2 0 Herpesvirus protein of unknown function (DUF832) HTH_5 PF01022.20 CBZ23485.1 - 0.017 15.0 0.4 5.6 6.9 0.0 2.9 2 0 0 2 2 2 0 Bacterial regulatory protein, arsR family BLACT_WH PF17778.1 CBZ23485.1 - 0.02 14.8 1.7 0.039 14.0 0.1 2.3 2 0 0 2 2 2 0 Beta-lactamase associated winged helix domain DUF2353 PF09789.9 CBZ23485.1 - 0.035 13.5 9.7 0.048 13.0 9.1 1.6 1 1 0 1 1 1 0 Uncharacterized coiled-coil protein (DUF2353) PhaP_Bmeg PF09602.10 CBZ23485.1 - 0.038 13.9 6.5 0.25 11.3 0.2 3.0 1 1 2 3 3 3 0 Polyhydroxyalkanoic acid inclusion protein (PhaP_Bmeg) Mit_ribos_Mrp51 PF11709.8 CBZ23485.1 - 0.056 13.0 2.0 0.072 12.7 1.2 1.5 1 1 0 1 1 1 0 Mitochondrial ribosomal protein subunit Pox_A_type_inc PF04508.12 CBZ23485.1 - 0.066 13.1 0.7 0.24 11.3 0.7 1.9 1 0 0 1 1 1 0 Viral A-type inclusion protein repeat bZIP_1 PF00170.21 CBZ23485.1 - 0.09 12.9 0.2 0.09 12.9 0.2 3.2 3 0 0 3 3 3 0 bZIP transcription factor FlaC_arch PF05377.11 CBZ23485.1 - 0.11 12.9 4.4 8.5 6.9 0.1 3.9 4 0 0 4 4 4 0 Flagella accessory protein C (FlaC) DivIC PF04977.15 CBZ23485.1 - 0.15 11.8 7.0 1.4 8.7 0.1 3.2 3 0 0 3 3 3 0 Septum formation initiator KASH_CCD PF14662.6 CBZ23485.1 - 0.48 10.2 13.2 0.1 12.4 7.2 2.4 2 1 0 2 2 2 0 Coiled-coil region of CCDC155 or KASH SOGA PF11365.8 CBZ23485.1 - 0.5 11.5 9.7 1 10.5 2.5 2.7 1 1 2 3 3 3 0 Protein SOGA HisKA PF00512.25 CBZ23485.1 - 0.81 9.8 4.9 13 5.9 0.1 3.5 3 0 0 3 3 3 0 His Kinase A (phospho-acceptor) domain Nnf1 PF03980.14 CBZ23485.1 - 0.85 10.0 11.5 4.3 7.8 0.8 3.4 2 1 0 2 2 2 0 Nnf1 DUF241 PF03087.14 CBZ23485.1 - 1.5 8.6 9.7 1.1 9.0 1.0 3.0 2 1 1 3 3 3 0 Arabidopsis protein of unknown function CdvA PF18822.1 CBZ23485.1 - 1.8 8.4 7.8 1.5 8.7 0.7 2.8 2 1 0 2 2 2 0 CdvA-like coiled-coil domain Uso1_p115_C PF04871.13 CBZ23485.1 - 3.1 8.2 10.2 0.8 10.1 3.3 2.5 1 1 1 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region DMPK_coil PF08826.10 CBZ23485.1 - 4 7.6 9.7 2.8 8.1 0.2 3.3 3 0 0 3 3 3 0 DMPK coiled coil domain like DUF1664 PF07889.12 CBZ23485.1 - 6.6 6.8 6.2 12 5.9 0.7 2.4 2 1 0 3 3 2 0 Protein of unknown function (DUF1664) ABC2_membrane PF01061.24 CBZ23487.1 - 6e-34 117.3 17.5 6e-34 117.3 17.5 1.7 2 0 0 2 2 2 1 ABC-2 type transporter ABC_tran PF00005.27 CBZ23487.1 - 1.9e-20 73.8 0.0 3e-20 73.1 0.0 1.3 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 CBZ23487.1 - 0.00094 18.7 0.0 0.11 11.9 0.0 2.2 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 CBZ23487.1 - 0.0017 18.3 1.0 0.27 11.0 0.0 2.6 3 0 0 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system NACHT PF05729.12 CBZ23487.1 - 0.0062 16.5 0.1 0.014 15.3 0.1 1.6 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 CBZ23487.1 - 0.0078 16.6 0.1 0.015 15.7 0.1 1.5 1 0 0 1 1 1 1 AAA ATPase domain RsgA_GTPase PF03193.16 CBZ23487.1 - 0.0088 16.0 0.0 0.015 15.2 0.0 1.3 1 0 0 1 1 1 1 RsgA GTPase DUF87 PF01935.17 CBZ23487.1 - 0.015 15.4 0.3 0.027 14.6 0.3 1.3 1 0 0 1 1 1 0 Helicase HerA, central domain AAA_23 PF13476.6 CBZ23487.1 - 0.021 15.3 0.0 0.034 14.7 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.6 CBZ23487.1 - 0.053 13.8 0.1 0.15 12.4 0.1 1.7 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 CBZ23487.1 - 0.071 13.2 0.2 0.15 12.2 0.2 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase TsaE PF02367.17 CBZ23487.1 - 0.11 12.5 0.1 0.56 10.2 0.1 2.2 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_29 PF13555.6 CBZ23487.1 - 0.16 11.8 0.2 0.33 10.7 0.2 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain NTPase_1 PF03266.15 CBZ23487.1 - 0.16 11.9 0.1 1.7 8.5 0.0 2.2 2 0 0 2 2 2 0 NTPase ABC2_membrane PF01061.24 CBZ23488.1 - 6.3e-36 123.8 17.4 6.3e-36 123.8 17.4 1.9 2 0 0 2 2 2 1 ABC-2 type transporter ABC_tran PF00005.27 CBZ23488.1 - 6.6e-21 75.3 0.0 9.8e-21 74.7 0.0 1.3 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 CBZ23488.1 - 0.00042 19.8 0.0 0.11 11.9 0.0 2.2 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 CBZ23488.1 - 0.00065 19.6 0.0 0.27 11.0 0.0 2.3 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 CBZ23488.1 - 0.0027 18.3 0.0 0.0042 17.6 0.0 1.2 1 0 0 1 1 1 1 AAA domain NACHT PF05729.12 CBZ23488.1 - 0.0043 17.0 0.2 0.01 15.8 0.2 1.6 1 0 0 1 1 1 1 NACHT domain RsgA_GTPase PF03193.16 CBZ23488.1 - 0.0066 16.4 0.0 0.011 15.6 0.0 1.3 1 0 0 1 1 1 1 RsgA GTPase DUF87 PF01935.17 CBZ23488.1 - 0.011 15.9 0.3 0.018 15.2 0.3 1.3 1 0 0 1 1 1 0 Helicase HerA, central domain AAA_16 PF13191.6 CBZ23488.1 - 0.02 15.3 0.1 0.037 14.4 0.1 1.5 1 0 0 1 1 1 0 AAA ATPase domain MMR_HSR1 PF01926.23 CBZ23488.1 - 0.04 14.0 0.1 0.08 13.0 0.1 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_19 PF13245.6 CBZ23488.1 - 0.042 14.2 0.0 0.11 12.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 CBZ23488.1 - 0.072 12.8 0.3 0.14 11.9 0.3 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain NTPase_1 PF03266.15 CBZ23488.1 - 0.12 12.3 0.1 1.2 9.1 0.0 2.2 2 0 0 2 2 2 0 NTPase TsaE PF02367.17 CBZ23488.1 - 0.14 12.2 0.5 0.47 10.5 0.2 2.0 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_22 PF13401.6 CBZ23488.1 - 0.19 12.0 0.1 0.7 10.2 0.0 1.9 2 0 0 2 2 1 0 AAA domain CytochromB561_N PF09786.9 CBZ23490.1 - 1e-05 24.8 0.0 1.8e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 Cytochrome B561, N terminal Pro_isomerase PF00160.21 CBZ23491.1 - 5.2e-51 173.1 0.1 5.9e-51 172.9 0.1 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD DUF1768 PF08719.11 CBZ23492.1 - 3.4e-24 85.9 0.0 4.2e-24 85.6 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1768) Proteasome PF00227.26 CBZ23493.1 - 8.4e-30 103.7 0.0 1.2e-29 103.2 0.0 1.2 1 0 0 1 1 1 1 Proteasome subunit HD PF01966.22 CBZ23495.1 - 5.1e-14 52.5 1.8 6e-14 52.3 0.3 1.9 2 0 0 2 2 2 1 HD domain PDEase_I PF00233.19 CBZ23495.1 - 0.00035 20.4 0.0 0.00068 19.4 0.0 1.4 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase HDOD PF08668.12 CBZ23495.1 - 0.00042 19.8 0.0 0.00075 19.0 0.0 1.3 1 0 0 1 1 1 1 HDOD domain Trm112p PF03966.16 CBZ23496.1 - 2.5e-07 31.2 0.0 1.5e-06 28.6 0.0 1.9 1 1 0 1 1 1 1 Trm112p-like protein zf-UDP PF14569.6 CBZ23496.1 - 0.088 12.9 0.0 0.27 11.4 0.0 1.8 2 0 0 2 2 2 0 Zinc-binding RING-finger L27 PF02828.16 CBZ23496.1 - 0.11 12.3 0.0 0.5 10.2 0.0 2.0 2 0 0 2 2 2 0 L27 domain zinc_ribbon_4 PF13717.6 CBZ23496.1 - 0.14 12.1 1.8 0.15 12.0 0.1 1.8 2 0 0 2 2 2 0 zinc-ribbon domain zinc_ribbon_5 PF13719.6 CBZ23496.1 - 0.17 11.7 1.6 0.37 10.6 0.3 2.0 2 0 0 2 2 2 0 zinc-ribbon domain Kinesin PF00225.23 CBZ23497.1 - 8.2e-71 238.6 0.0 1.1e-70 238.2 0.0 1.1 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 CBZ23497.1 - 2.5e-11 43.7 0.0 4e-09 36.6 0.0 2.4 2 0 0 2 2 2 2 Microtubule binding Nnf1 PF03980.14 CBZ23497.1 - 0.27 11.6 2.3 21 5.5 0.2 2.8 3 0 0 3 3 3 0 Nnf1 FHA PF00498.26 CBZ23500.1 - 2.9e-10 40.3 0.0 2.9e-09 37.2 0.0 2.3 1 1 0 1 1 1 1 FHA domain DUF3498 PF12004.8 CBZ23500.1 - 2 7.5 11.5 0.13 11.4 0.6 2.7 2 1 0 3 3 3 0 Domain of unknown function (DUF3498) DUF4490 PF14892.6 CBZ23501.1 - 0.007 16.4 0.2 0.012 15.6 0.2 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4490) zf-NADH-PPase PF09297.11 CBZ23501.1 - 0.14 11.9 0.1 0.36 10.5 0.1 1.7 1 0 0 1 1 1 0 NADH pyrophosphatase zinc ribbon domain Leu_zip PF15294.6 CBZ23504.1 - 2.8e-12 46.8 12.4 4.3e-06 26.4 2.3 2.5 1 1 0 2 2 2 2 Leucine zipper V-ATPase_G_2 PF16999.5 CBZ23504.1 - 0.0098 16.3 4.5 0.0098 16.3 4.5 2.7 2 1 1 3 3 3 1 Vacuolar (H+)-ATPase G subunit Jnk-SapK_ap_N PF09744.9 CBZ23504.1 - 0.33 11.1 9.1 0.77 10.0 9.1 1.6 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 FAM76 PF16046.5 CBZ23504.1 - 0.39 10.0 2.8 0.57 9.5 2.8 1.2 1 0 0 1 1 1 0 FAM76 protein FliJ PF02050.16 CBZ23504.1 - 0.48 10.7 18.7 0.26 11.5 7.7 2.8 1 1 2 3 3 3 0 Flagellar FliJ protein UPF0449 PF15136.6 CBZ23504.1 - 0.6 10.6 6.7 0.11 12.9 0.8 2.5 2 1 0 3 3 3 0 Uncharacterised protein family UPF0449 TMF_TATA_bd PF12325.8 CBZ23504.1 - 3 8.1 14.1 1.6 9.0 2.4 2.4 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding T3SS_needle_F PF09392.10 CBZ23504.1 - 3.4 7.9 5.5 0.93 9.7 1.1 2.3 2 1 1 3 3 3 0 Type III secretion needle MxiH, YscF, SsaG, EprI, PscF, EscF ATG16 PF08614.11 CBZ23504.1 - 3.5 7.8 18.5 0.15 12.2 5.3 2.4 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) Exonuc_VII_L PF02601.15 CBZ23504.1 - 4.6 6.7 12.3 6 6.3 12.2 1.4 1 1 0 1 1 1 0 Exonuclease VII, large subunit DUF1664 PF07889.12 CBZ23504.1 - 4.6 7.3 8.1 3.1 7.9 0.9 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) GAS PF13851.6 CBZ23504.1 - 4.7 6.5 12.6 5.4 6.3 6.2 2.2 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding HAUS6_N PF14661.6 CBZ23504.1 - 5.4 6.5 10.3 10 5.6 5.6 2.2 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 6 N-terminus XRN_N PF03159.18 CBZ23505.1 - 2.7e-90 302.0 0.0 4.7e-90 301.3 0.0 1.4 1 0 0 1 1 1 1 XRN 5'-3' exonuclease N-terminus XRN_M PF17846.1 CBZ23505.1 - 1.8e-83 280.9 6.1 6.9e-55 186.8 1.4 2.5 2 1 1 3 3 3 2 Xrn1 helical domain XRN1_D1 PF18332.1 CBZ23505.1 - 1.9e-22 79.9 0.1 3.1e-22 79.3 0.1 1.3 1 0 0 1 1 1 1 Exoribonuclease Xrn1 D1 domain SH3_12 PF18129.1 CBZ23505.1 - 5.3e-16 58.5 0.2 2.6e-15 56.3 0.0 2.1 2 0 0 2 2 2 1 Xrn1 SH3-like domain Trypan_PARP PF05887.11 CBZ23505.1 - 0.00057 19.9 1.0 0.0015 18.5 1.0 1.7 1 0 0 1 1 1 1 Procyclic acidic repetitive protein (PARP) ORC2 PF04084.14 CBZ23505.1 - 0.04 12.8 0.0 0.076 11.9 0.0 1.4 1 0 0 1 1 1 0 Origin recognition complex subunit 2 DUF3391 PF11871.8 CBZ23505.1 - 4.2 7.9 7.1 3 8.4 2.4 3.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3391) FHA PF00498.26 CBZ23507.1 - 0.012 15.9 0.0 0.025 14.9 0.0 1.4 1 0 0 1 1 1 0 FHA domain RNase_H PF00075.24 CBZ23508.1 - 3.3e-28 98.7 0.7 1.4e-19 70.6 0.0 3.0 1 1 1 2 2 2 2 RNase H NDUF_B6 PF09782.9 CBZ23508.1 - 0.15 12.2 0.7 0.22 11.7 0.7 1.2 1 0 0 1 1 1 0 NADH:ubiquinone oxidoreductase, NDUFB6/B17 subunit zf-MYND PF01753.18 CBZ23509.1 - 4.6e-12 45.8 15.2 4.6e-12 45.8 15.2 1.9 3 0 0 3 3 3 1 MYND finger zf-Mss51 PF13824.6 CBZ23509.1 - 0.75 9.9 7.2 1.5 9.0 7.2 1.5 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 zf-C6H2 PF15801.5 CBZ23509.1 - 1.5 9.2 14.4 0.41 11.0 9.3 2.5 2 1 0 2 2 2 0 zf-MYND-like zinc finger, mRNA-binding BT1 PF03092.16 CBZ23510.1 - 4.5e-193 642.2 10.9 5.2e-193 642.0 10.9 1.0 1 0 0 1 1 1 1 BT1 family SAM_LFY PF01698.16 CBZ23510.1 - 0.1 12.6 0.0 0.26 11.3 0.0 1.7 1 1 0 1 1 1 0 Floricaula / Leafy protein SAM domain TPR_2 PF07719.17 CBZ23512.1 - 0.00059 19.8 9.5 0.66 10.2 0.8 4.1 3 0 0 3 3 3 3 Tetratricopeptide repeat GOLGA2L5 PF15070.6 CBZ23512.1 - 0.0053 15.5 6.3 0.0086 14.8 6.3 1.2 1 0 0 1 1 1 1 Putative golgin subfamily A member 2-like protein 5 COX6C PF02937.15 CBZ23512.1 - 0.19 11.9 0.0 0.47 10.6 0.0 1.6 1 0 0 1 1 1 0 Cytochrome c oxidase subunit VIc Sel1 PF08238.12 CBZ23512.1 - 0.35 11.6 4.8 0.39 11.5 0.2 2.8 2 0 0 2 2 2 0 Sel1 repeat TPR_1 PF00515.28 CBZ23512.1 - 0.38 10.7 4.3 2.4 8.1 0.5 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat Peptidase_S9 PF00326.21 CBZ23513.1 - 6e-33 114.1 0.0 1.5e-32 112.8 0.0 1.6 2 0 0 2 2 2 1 Prolyl oligopeptidase family Peptidase_S9_N PF02897.15 CBZ23513.1 - 1.5e-27 96.5 0.0 2.5e-27 95.7 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase, N-terminal beta-propeller domain 3Beta_HSD PF01073.19 CBZ23514.1 - 2.9e-28 98.7 0.0 3.6e-28 98.4 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 CBZ23514.1 - 4.3e-18 65.6 0.0 5.4e-18 65.3 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 CBZ23514.1 - 6.2e-10 39.3 0.0 8.3e-10 38.9 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding NAD_binding_4 PF07993.12 CBZ23514.1 - 1.1e-08 34.5 0.0 1.6e-08 34.1 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein GDP_Man_Dehyd PF16363.5 CBZ23514.1 - 3e-05 23.6 0.0 5.6e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 CBZ23514.1 - 0.00064 18.9 0.0 0.001 18.3 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NmrA PF05368.13 CBZ23514.1 - 0.0014 18.2 0.0 0.0022 17.6 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family Gln-synt_C PF00120.24 CBZ23516.1 - 1.3e-18 67.1 0.0 4.6e-18 65.3 0.0 1.7 1 1 0 1 1 1 1 Glutamine synthetase, catalytic domain Gln-synt_N PF03951.19 CBZ23516.1 - 5.6e-14 51.6 0.0 1.1e-13 50.7 0.0 1.5 1 0 0 1 1 1 1 Glutamine synthetase, beta-Grasp domain zf_CCCH_4 PF18345.1 CBZ23517.1 - 1.2e-06 28.4 2.6 2.6e-06 27.3 2.6 1.6 1 0 0 1 1 1 1 Zinc finger domain zf-CCCH PF00642.24 CBZ23517.1 - 3.5e-06 26.8 1.7 7.9e-06 25.7 1.7 1.6 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 CBZ23517.1 - 4.8e-06 26.2 0.7 9.6e-06 25.3 0.7 1.5 1 0 0 1 1 1 1 CCCH-type zinc finger Torus PF16131.5 CBZ23517.1 - 0.00089 19.9 0.1 0.0022 18.7 0.1 1.6 1 0 0 1 1 1 1 Torus domain zf-CCCH_2 PF14608.6 CBZ23517.1 - 0.061 13.8 1.4 0.061 13.8 1.4 1.9 2 0 0 2 2 2 0 RNA-binding, Nab2-type zinc finger LRR_6 PF13516.6 CBZ23517.1 - 0.14 12.3 0.0 3.4 8.0 0.0 2.4 2 0 0 2 2 2 0 Leucine Rich repeat Ribosomal_L19e PF01280.20 CBZ23520.1 - 5.9e-60 201.5 11.3 5.9e-60 201.5 11.3 2.1 2 0 0 2 2 2 1 Ribosomal protein L19e Rrn6 PF10214.9 CBZ23520.1 - 0.58 8.6 7.2 0.77 8.2 7.2 1.2 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor HTH_35 PF13693.6 CBZ23521.1 - 0.11 12.6 0.2 2.8 8.0 0.1 2.4 1 1 1 2 2 2 0 Winged helix-turn-helix DNA-binding Ribosomal_L19e PF01280.20 CBZ23522.1 - 5.9e-60 201.5 11.3 5.9e-60 201.5 11.3 2.1 2 0 0 2 2 2 1 Ribosomal protein L19e Rrn6 PF10214.9 CBZ23522.1 - 0.58 8.6 7.2 0.77 8.2 7.2 1.2 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor Kinesin PF00225.23 CBZ23524.1 - 7.6e-10 38.2 5.3 0.00012 21.2 0.0 3.1 3 0 0 3 3 3 2 Kinesin motor domain AAA_13 PF13166.6 CBZ23524.1 - 0.017 13.8 7.9 0.026 13.2 7.9 1.2 1 0 0 1 1 1 0 AAA domain SCAB_CC PF16712.5 CBZ23524.1 - 0.19 11.6 12.8 0.18 11.6 9.6 2.2 2 0 0 2 2 2 0 Coiled-coil regions of plant-specific actin-binding protein DUF1664 PF07889.12 CBZ23524.1 - 0.58 10.2 13.0 0.039 14.0 2.9 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) MCPsignal PF00015.21 CBZ23524.1 - 0.7 9.7 16.0 0.27 11.0 7.7 3.1 3 0 0 3 3 3 0 Methyl-accepting chemotaxis protein (MCP) signalling domain DUF913 PF06025.12 CBZ23524.1 - 1.2 8.0 10.1 3 6.7 9.2 2.1 2 1 0 2 2 2 0 Domain of Unknown Function (DUF913) DUF948 PF06103.11 CBZ23524.1 - 1.4 9.2 5.2 4.3 7.7 0.6 3.4 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) TMF_DNA_bd PF12329.8 CBZ23524.1 - 1.8 8.6 13.8 0.44 10.6 8.2 2.4 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding DUF2730 PF10805.8 CBZ23524.1 - 3.7 7.7 8.6 0.42 10.7 3.1 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF2730) TPR_12 PF13424.6 CBZ23525.1 - 3.6e-06 27.2 0.2 0.0044 17.3 0.1 2.8 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_10 PF13374.6 CBZ23525.1 - 9.3e-06 25.3 0.4 0.042 13.7 0.0 3.0 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.28 CBZ23525.1 - 0.00073 19.3 1.9 0.034 14.0 0.0 3.4 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.17 CBZ23525.1 - 0.0084 16.1 0.1 0.052 13.7 0.0 2.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.6 CBZ23525.1 - 0.02 14.9 0.1 7.3 6.9 0.0 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat HrpF PF06266.12 CBZ23525.1 - 0.03 14.6 1.6 0.48 10.7 0.0 2.8 2 1 1 3 3 3 0 HrpF protein TPR_19 PF14559.6 CBZ23525.1 - 0.079 13.5 1.4 0.34 11.4 0.3 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat NAD_kinase PF01513.21 CBZ23527.1 - 1.2e-08 34.6 0.0 2.9e-08 33.3 0.0 1.6 1 0 0 1 1 1 1 ATP-NAD kinase Cnd2 PF05786.14 CBZ23528.1 - 6.4e-25 88.0 10.6 7.8e-18 64.5 0.2 3.2 3 0 0 3 3 3 2 Condensin complex subunit 2 CNDH2_N PF06278.11 CBZ23528.1 - 0.01 16.0 0.0 0.028 14.6 0.0 1.7 1 0 0 1 1 1 0 Condensin II complex subunit CAP-H2 or CNDH2, N-terminal SpoU_methylase PF00588.19 CBZ23531.1 - 1.1e-15 58.0 0.0 7.3e-13 48.9 0.0 3.1 2 1 0 2 2 2 1 SpoU rRNA Methylase family SpoU_sub_bind PF08032.12 CBZ23531.1 - 1.2e-05 25.4 0.0 0.00015 22.0 0.0 2.3 2 0 0 2 2 2 1 RNA 2'-O ribose methyltransferase substrate binding U-box PF04564.15 CBZ23532.1 - 4.2e-12 46.1 0.0 9.6e-12 44.9 0.0 1.6 1 0 0 1 1 1 1 U-box domain zf-NOSIP PF15906.5 CBZ23532.1 - 0.14 12.3 0.0 0.32 11.2 0.0 1.5 1 0 0 1 1 1 0 Zinc-finger of nitric oxide synthase-interacting protein LRR_4 PF12799.7 CBZ23533.1 - 6.4e-12 45.5 3.3 0.091 13.2 0.0 8.5 8 3 2 10 10 10 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CBZ23533.1 - 8.2e-06 25.5 2.8 4.8 7.0 0.4 6.9 8 0 0 8 8 8 2 Leucine rich repeat LRR_6 PF13516.6 CBZ23533.1 - 0.0011 18.8 9.0 11 6.4 0.1 7.4 9 0 0 9 9 9 2 Leucine Rich repeat Maf_N PF08383.11 CBZ23534.1 - 0.23 11.3 0.2 0.23 11.3 0.2 2.2 2 0 0 2 2 2 0 Maf N-terminal region dUTPase_2 PF08761.11 CBZ23537.1 - 8e-46 156.2 0.0 1.2e-45 155.7 0.0 1.3 1 0 0 1 1 1 1 dUTPase Ribosomal_L23 PF00276.20 CBZ23538.1 - 3.9e-16 59.2 3.3 3.9e-16 59.2 3.3 2.6 2 1 0 2 2 2 1 Ribosomal protein L23 Ribosomal_L23eN PF03939.13 CBZ23538.1 - 0.0036 17.5 9.3 0.0036 17.5 9.3 1.9 2 0 0 2 2 2 1 Ribosomal protein L23, N-terminal domain TusA PF01206.17 CBZ23538.1 - 0.014 15.2 1.0 0.022 14.6 0.1 1.8 2 0 0 2 2 2 0 Sulfurtransferase TusA Ribosomal_L23 PF00276.20 CBZ23539.1 - 3.9e-16 59.2 3.3 3.9e-16 59.2 3.3 2.6 2 1 0 2 2 2 1 Ribosomal protein L23 Ribosomal_L23eN PF03939.13 CBZ23539.1 - 0.0036 17.5 9.3 0.0036 17.5 9.3 1.9 2 0 0 2 2 2 1 Ribosomal protein L23, N-terminal domain TusA PF01206.17 CBZ23539.1 - 0.014 15.2 1.0 0.022 14.6 0.1 1.8 2 0 0 2 2 2 0 Sulfurtransferase TusA PHD PF00628.29 CBZ23541.1 - 0.00018 21.4 0.9 0.00018 21.4 0.9 1.9 2 0 0 2 2 2 1 PHD-finger PHD_4 PF16866.5 CBZ23541.1 - 1.6 8.9 3.5 1.2 9.2 1.1 1.9 2 0 0 2 2 2 0 PHD-finger Pro_CA PF00484.19 CBZ23542.1 - 2.8e-42 144.7 2.1 1.5e-40 139.0 2.1 2.2 1 1 0 1 1 1 1 Carbonic anhydrase DUF89 PF01937.19 CBZ23543.1 - 5.1e-41 140.8 0.0 3.3e-21 75.6 0.0 4.6 4 1 0 4 4 4 4 Protein of unknown function DUF89 Put_Phosphatase PF06888.12 CBZ23543.1 - 5.1e-33 114.4 0.7 7.4e-15 55.0 0.0 3.4 3 0 0 3 3 3 3 Putative Phosphatase Pkinase PF00069.25 CBZ23545.1 - 1.9e-46 158.6 0.0 3.3e-45 154.5 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ23545.1 - 4e-31 108.2 0.0 1.4e-22 80.2 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase FHA PF00498.26 CBZ23545.1 - 3.7e-09 36.8 0.0 6.9e-09 35.9 0.0 1.5 1 0 0 1 1 1 1 FHA domain Kinase-like PF14531.6 CBZ23545.1 - 0.0038 16.6 0.0 0.008 15.5 0.0 1.4 1 0 0 1 1 1 1 Kinase-like PAS PF00989.25 CBZ23545.1 - 0.0042 17.1 0.0 0.33 11.0 0.0 2.7 2 0 0 2 2 2 1 PAS fold Pkinase_fungal PF17667.1 CBZ23545.1 - 0.048 12.4 0.0 0.08 11.7 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase SQHop_cyclase_N PF13249.6 CBZ23546.1 - 4.8e-45 153.9 1.2 1.5e-41 142.4 0.1 3.4 4 0 0 4 4 4 2 Squalene-hopene cyclase N-terminal domain SQHop_cyclase_C PF13243.6 CBZ23546.1 - 5.8e-35 120.9 3.3 2.3e-31 109.1 0.7 2.9 3 0 0 3 3 3 2 Squalene-hopene cyclase C-terminal domain Prenyltrans PF00432.21 CBZ23546.1 - 1.7e-19 69.3 10.9 3.4e-08 33.1 0.0 5.7 5 1 0 5 5 5 3 Prenyltransferase and squalene oxidase repeat TED_complement PF07678.14 CBZ23546.1 - 0.073 12.1 0.0 0.2 10.7 0.0 1.7 1 0 0 1 1 1 0 A-macroglobulin TED domain NDUF_B7 PF05676.13 CBZ23549.1 - 5.8e-05 22.7 3.9 0.0001 21.9 3.9 1.3 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) Cmc1 PF08583.10 CBZ23549.1 - 0.00062 19.7 3.4 0.0011 19.0 3.4 1.3 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like Pet191_N PF10203.9 CBZ23549.1 - 0.29 11.5 3.3 0.5 10.7 3.3 1.3 1 0 0 1 1 1 0 Cytochrome c oxidase assembly protein PET191 CHCH PF06747.13 CBZ23549.1 - 1.2 9.3 4.6 2 8.7 4.6 1.4 1 0 0 1 1 1 0 CHCH domain Ctf8 PF09696.10 CBZ23550.1 - 1.4e-09 38.4 0.0 0.00012 22.4 0.0 3.2 3 0 0 3 3 3 3 Ctf8 AAA_lid_7 PF17867.1 CBZ23551.1 - 0.089 13.0 0.1 0.39 10.9 0.1 2.2 1 0 0 1 1 1 0 Midasin AAA lid domain DZR PF12773.7 CBZ23551.1 - 1 9.4 11.7 1.1 9.4 0.3 3.7 4 0 0 4 4 4 0 Double zinc ribbon HypA PF01155.19 CBZ23551.1 - 4.9 7.2 5.2 8.4 6.5 0.1 3.1 3 0 0 3 3 3 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA C2 PF00168.30 CBZ23552.1 - 2.6e-08 34.1 0.0 4.4e-08 33.3 0.0 1.3 1 0 0 1 1 1 1 C2 domain Ank_2 PF12796.7 CBZ23552.1 - 1.2e-07 32.2 0.0 6.7e-07 29.8 0.0 2.2 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CBZ23552.1 - 1.3e-06 28.8 0.1 0.0079 16.8 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 CBZ23552.1 - 3.6e-06 27.2 0.2 0.063 13.8 0.0 2.8 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.6 CBZ23552.1 - 4e-06 27.0 0.3 0.038 14.3 0.0 3.3 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 CBZ23552.1 - 0.025 15.1 0.3 16 6.5 0.0 3.1 3 0 0 3 3 3 0 Ankyrin repeat YEATS PF03366.16 CBZ23554.1 - 4.3e-15 55.4 0.0 7.9e-15 54.6 0.0 1.4 1 0 0 1 1 1 1 YEATS family SDA1 PF05285.12 CBZ23554.1 - 1.1 8.6 12.4 1.9 7.8 12.4 1.3 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.12 CBZ23554.1 - 1.9 6.6 9.3 3.1 5.9 9.3 1.2 1 0 0 1 1 1 0 Nop14-like family DUF3947 PF13135.6 CBZ23554.1 - 3.3 8.0 4.6 0.91 9.8 1.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3947) PALP PF00291.25 CBZ23555.1 - 5.8e-56 190.0 0.3 6.6e-56 189.9 0.3 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme HlyIII PF03006.20 CBZ23557.1 - 7.1e-12 45.5 20.4 5.9e-05 22.9 0.1 3.0 2 1 0 2 2 2 2 Haemolysin-III related RRM_1 PF00076.22 CBZ23559.1 - 2e-26 91.6 0.0 1.4e-13 50.4 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 CBZ23559.1 - 0.00092 19.0 0.0 0.0021 17.9 0.0 1.6 1 0 0 1 1 1 1 Occluded RNA-recognition motif Glyoxalase PF00903.25 CBZ23563.1 - 0.015 15.5 0.0 0.042 14.0 0.0 1.8 2 0 0 2 2 2 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily DUF4618 PF15397.6 CBZ23563.1 - 0.065 12.6 1.6 1.4 8.3 0.1 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4618) IFT57 PF10498.9 CBZ23563.1 - 0.15 11.0 3.6 0.29 10.1 0.1 2.2 2 0 0 2 2 2 0 Intra-flagellar transport protein 57 ADIP PF11559.8 CBZ23563.1 - 0.18 11.9 11.7 1.3 9.1 0.8 2.6 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding Phage_tail_T PF06223.12 CBZ23563.1 - 0.19 12.3 1.0 0.51 10.9 0.1 2.1 2 0 0 2 2 2 0 Minor tail protein T Spc24 PF08286.11 CBZ23563.1 - 0.45 10.8 3.1 3 8.1 0.3 2.7 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 DUF4200 PF13863.6 CBZ23563.1 - 1.7 9.1 10.9 1.2 9.6 0.6 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4200) YlqD PF11068.8 CBZ23563.1 - 2.8 8.3 7.6 3 8.2 0.4 2.7 3 0 0 3 3 3 0 YlqD protein GCN5L1 PF06320.13 CBZ23563.1 - 5.3 7.2 6.9 1.4 9.0 0.4 2.7 3 0 0 3 3 3 0 GCN5-like protein 1 (GCN5L1) APG6_N PF17675.1 CBZ23563.1 - 5.9 7.4 22.4 1.2 9.6 1.0 3.2 2 1 1 3 3 3 0 Apg6 coiled-coil region LNS2 PF08235.13 CBZ23564.1 - 2.9e-82 275.5 0.0 4.2e-82 275.0 0.0 1.2 1 0 0 1 1 1 1 LNS2 (Lipin/Ned1/Smp2) Lipin_N PF04571.14 CBZ23564.1 - 1.7e-17 63.2 0.0 3.9e-17 62.1 0.0 1.5 1 0 0 1 1 1 1 lipin, N-terminal conserved region Acid_phosphat_B PF03767.14 CBZ23564.1 - 0.05 13.2 0.0 0.1 12.2 0.0 1.4 1 0 0 1 1 1 0 HAD superfamily, subfamily IIIB (Acid phosphatase) Med3 PF11593.8 CBZ23565.1 - 0.39 9.8 12.0 0.5 9.5 12.0 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal EF-hand_1 PF00036.32 CBZ23566.1 - 0.058 13.0 0.0 0.13 11.8 0.0 1.6 1 0 0 1 1 1 0 EF hand EF-hand_7 PF13499.6 CBZ23566.1 - 0.14 12.6 0.0 0.29 11.6 0.0 1.5 1 0 0 1 1 1 0 EF-hand domain pair NARP1 PF12569.8 CBZ23566.1 - 0.61 8.9 5.2 1 8.2 5.2 1.2 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Thymidylat_synt PF00303.19 CBZ23567.1 - 1.9e-107 358.4 0.0 2.5e-107 358.0 0.0 1.2 1 0 0 1 1 1 1 Thymidylate synthase DHFR_1 PF00186.19 CBZ23567.1 - 2.1e-24 86.1 0.0 2.1e-23 82.8 0.0 2.4 1 1 0 1 1 1 1 Dihydrofolate reductase Spo12 PF05032.12 CBZ23567.1 - 0.14 12.0 0.0 0.32 10.9 0.0 1.5 1 0 0 1 1 1 0 Spo12 family PrmA PF06325.13 CBZ23568.1 - 1.2e-08 34.8 0.0 2.3e-08 33.8 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_25 PF13649.6 CBZ23568.1 - 2.7e-06 28.0 0.0 7.4e-06 26.6 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_16 PF10294.9 CBZ23568.1 - 2.1e-05 24.3 0.0 3.2e-05 23.7 0.0 1.2 1 0 0 1 1 1 1 Lysine methyltransferase MTS PF05175.14 CBZ23568.1 - 3e-05 23.6 0.0 5.8e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Cons_hypoth95 PF03602.15 CBZ23568.1 - 0.0001 22.0 0.0 0.00017 21.3 0.0 1.3 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Met_10 PF02475.16 CBZ23568.1 - 0.0014 18.4 0.0 0.0024 17.6 0.0 1.4 1 0 0 1 1 1 1 Met-10+ like-protein PCMT PF01135.19 CBZ23568.1 - 0.002 17.9 0.0 0.0034 17.2 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) RrnaAD PF00398.20 CBZ23568.1 - 0.0027 16.8 0.0 0.0042 16.2 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_12 PF08242.12 CBZ23568.1 - 0.017 15.8 0.2 0.076 13.8 0.0 2.3 3 0 0 3 3 3 0 Methyltransferase domain Methyltransf_11 PF08241.12 CBZ23568.1 - 0.018 15.7 0.0 0.044 14.4 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain CMAS PF02353.20 CBZ23568.1 - 0.026 13.8 0.0 0.039 13.2 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.6 CBZ23568.1 - 0.1 12.4 0.0 0.2 11.5 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_18 PF12847.7 CBZ23568.1 - 0.12 12.4 0.0 0.21 11.5 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Acyl-CoA_dh_1 PF00441.24 CBZ23569.1 - 1.5e-47 161.6 3.1 2.4e-47 160.9 3.1 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 CBZ23569.1 - 9.4e-27 93.9 0.3 2.3e-26 92.6 0.3 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 CBZ23569.1 - 1.3e-26 92.6 0.3 3.9e-26 91.1 0.3 1.9 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 CBZ23569.1 - 3.1e-20 72.8 1.0 5e-20 72.1 1.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain HpaB_N PF11794.8 CBZ23569.1 - 0.00084 19.1 0.2 0.0035 17.0 0.2 2.0 1 1 0 1 1 1 1 4-hydroxyphenylacetate 3-hydroxylase N terminal PP2C PF00481.21 CBZ23571.1 - 2.7e-25 89.5 0.0 1.3e-16 61.0 0.0 3.4 3 0 0 3 3 3 2 Protein phosphatase 2C SpoIIE PF07228.12 CBZ23571.1 - 0.018 15.0 0.0 0.062 13.2 0.0 1.9 1 0 0 1 1 1 0 Stage II sporulation protein E (SpoIIE) PTH2 PF01981.16 CBZ23572.1 - 2.3e-46 156.9 0.6 3.5e-46 156.3 0.6 1.3 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase PTH2 Oxidored_FMN PF00724.20 CBZ23574.1 - 1.9e-42 145.8 0.0 2.4e-42 145.4 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Pyr_redox_2 PF07992.14 CBZ23574.1 - 3.9e-15 55.9 0.0 1.5e-14 54.0 0.0 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 CBZ23574.1 - 2.7e-10 40.3 0.0 1e-09 38.5 0.0 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 CBZ23574.1 - 1.5e-07 30.9 0.0 2.4e-07 30.2 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 CBZ23574.1 - 1.7e-06 27.9 0.0 3.1e-06 27.0 0.0 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_oxidored PF12831.7 CBZ23574.1 - 1.9e-06 27.5 0.6 4.7e-06 26.2 0.7 1.6 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 CBZ23574.1 - 2.3e-06 28.1 0.6 0.00045 20.7 0.4 3.4 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 CBZ23574.1 - 4e-06 25.8 1.5 5.7e-06 25.3 0.1 2.0 3 0 0 3 3 3 1 HI0933-like protein GIDA PF01134.22 CBZ23574.1 - 0.0012 18.0 0.3 0.0019 17.4 0.3 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A Pyr_redox_3 PF13738.6 CBZ23574.1 - 0.0015 17.8 0.3 0.01 15.1 0.0 2.1 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 CBZ23574.1 - 0.0031 16.8 0.1 0.005 16.2 0.1 1.3 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase Thi4 PF01946.17 CBZ23574.1 - 0.0047 16.2 0.1 0.0093 15.2 0.1 1.4 1 0 0 1 1 1 1 Thi4 family FAD_binding_3 PF01494.19 CBZ23574.1 - 0.0086 15.4 0.1 0.015 14.6 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain ApbA PF02558.16 CBZ23574.1 - 0.023 14.3 0.2 0.071 12.8 0.2 1.8 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA 3HCDH_N PF02737.18 CBZ23574.1 - 0.045 13.6 0.0 0.088 12.7 0.0 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_7 PF13241.6 CBZ23574.1 - 0.058 13.8 0.2 1.1 9.7 0.0 2.5 2 0 0 2 2 2 0 Putative NAD(P)-binding NAD_Gly3P_dh_N PF01210.23 CBZ23574.1 - 0.065 13.2 0.1 0.15 12.1 0.1 1.6 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_binding_9 PF13454.6 CBZ23574.1 - 0.086 12.8 0.1 0.2 11.7 0.1 1.6 1 0 0 1 1 1 0 FAD-NAD(P)-binding FMO-like PF00743.19 CBZ23574.1 - 0.11 10.9 0.1 2.2 6.6 0.0 2.1 2 0 0 2 2 2 0 Flavin-binding monooxygenase-like TLD PF07534.16 CBZ23575.1 - 2.6e-08 34.2 0.0 9.7e-05 22.6 0.0 3.2 3 0 0 3 3 3 3 TLD SIS PF01380.22 CBZ23576.1 - 1.1e-49 167.6 1.8 1.3e-26 93.0 0.1 2.3 2 0 0 2 2 2 2 SIS domain GATase_6 PF13522.6 CBZ23576.1 - 1.4e-14 54.5 0.0 3.7e-14 53.1 0.0 1.7 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.6 CBZ23576.1 - 7.9e-09 35.5 0.0 2e-08 34.2 0.0 1.7 1 0 0 1 1 1 1 Glutamine amidotransferase domain DUF2529 PF10740.9 CBZ23576.1 - 0.0018 17.9 0.2 0.012 15.2 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF2529) GATase_4 PF13230.6 CBZ23576.1 - 0.008 15.1 0.0 0.018 14.0 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferases class-II SIS_2 PF13580.6 CBZ23576.1 - 0.044 13.8 0.0 1.3 9.0 0.0 2.6 2 0 0 2 2 2 0 SIS domain Mob1_phocein PF03637.17 CBZ23577.1 - 2.9e-69 232.4 0.2 3.6e-69 232.1 0.2 1.0 1 0 0 1 1 1 1 Mob1/phocein family DUF3883 PF13020.6 CBZ23578.1 - 2e-17 63.0 0.0 4.2e-17 62.0 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3883) LRR_8 PF13855.6 CBZ23579.1 - 1.5e-23 82.4 11.3 1.3e-08 34.4 0.8 4.9 5 0 0 5 5 5 4 Leucine rich repeat LRR_4 PF12799.7 CBZ23579.1 - 3.6e-16 59.0 9.1 0.012 16.0 0.0 6.8 5 2 1 6 6 6 6 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 CBZ23579.1 - 9.7e-05 22.4 18.8 9.5 7.2 0.1 10.5 11 1 0 11 11 11 1 Leucine Rich Repeat LRR_9 PF14580.6 CBZ23579.1 - 0.0011 18.6 1.5 0.34 10.4 0.4 3.4 3 1 0 3 3 3 1 Leucine-rich repeat GRDP-like PF07173.12 CBZ23579.1 - 0.019 15.6 4.1 8 7.1 0.1 4.0 3 1 1 4 4 4 0 Glycine-rich domain-containing protein-like LRR_6 PF13516.6 CBZ23579.1 - 0.44 10.7 21.9 15 6.0 0.0 9.0 11 0 0 11 11 11 0 Leucine Rich repeat DUF3024 PF11225.8 CBZ23579.1 - 0.87 9.9 3.3 0.34 11.2 0.3 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3024) SET PF00856.28 CBZ23582.1 - 1.7e-16 61.0 0.0 3e-16 60.3 0.0 1.4 1 0 0 1 1 1 1 SET domain zf-MYND PF01753.18 CBZ23582.1 - 0.00014 21.8 11.1 0.00014 21.8 11.1 2.9 3 1 0 3 3 3 1 MYND finger TFIIF_beta PF02270.15 CBZ23582.1 - 0.16 12.1 0.0 0.35 11.0 0.0 1.5 1 0 0 1 1 1 0 TFIIF, beta subunit HTH domain G-patch PF01585.23 CBZ23584.1 - 3.1e-12 46.2 1.2 5.3e-12 45.4 1.2 1.4 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 CBZ23584.1 - 7.1e-08 32.4 0.6 1.8e-07 31.1 0.6 1.6 1 0 0 1 1 1 1 G-patch domain Kinesin PF00225.23 CBZ23585.1 - 8.6e-63 212.3 0.0 1.9e-62 211.1 0.0 1.5 1 1 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 CBZ23585.1 - 7.2e-11 42.2 0.0 1.5e-10 41.2 0.0 1.6 1 0 0 1 1 1 1 Microtubule binding BRE1 PF08647.11 CBZ23585.1 - 0.012 15.7 1.2 0.012 15.7 1.2 1.8 2 0 0 2 2 2 0 BRE1 E3 ubiquitin ligase AAA_7 PF12775.7 CBZ23585.1 - 0.058 12.9 0.0 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_22 PF13401.6 CBZ23585.1 - 0.082 13.2 0.1 0.34 11.2 0.0 2.1 2 0 0 2 2 2 0 AAA domain DUF87 PF01935.17 CBZ23585.1 - 0.21 11.6 0.0 0.52 10.4 0.0 1.6 1 0 0 1 1 1 0 Helicase HerA, central domain ABC_tran_CTD PF16326.5 CBZ23586.1 - 0.0035 17.5 0.2 0.0035 17.5 0.2 6.3 5 2 2 7 7 7 2 ABC transporter C-terminal domain THOC7 PF05615.13 CBZ23586.1 - 0.27 11.5 42.6 0.27 11.5 15.5 4.4 4 0 0 4 4 4 0 Tho complex subunit 7 YcbB PF08664.10 CBZ23586.1 - 3.6 7.6 8.9 11 6.1 2.4 3.0 2 0 0 2 2 2 0 YcbB domain Thioredoxin PF00085.20 CBZ23587.1 - 3.4e-26 91.2 0.0 4e-26 91.0 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 CBZ23587.1 - 1.9e-06 28.3 0.1 4e-06 27.3 0.1 1.5 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_7 PF13899.6 CBZ23587.1 - 0.00011 22.3 0.0 0.00016 21.8 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin-like TraF PF13728.6 CBZ23587.1 - 0.00058 19.8 0.0 0.00079 19.3 0.0 1.2 1 0 0 1 1 1 1 F plasmid transfer operon protein OST3_OST6 PF04756.13 CBZ23587.1 - 0.0012 18.3 0.0 0.0014 18.0 0.0 1.1 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin_5 PF13743.6 CBZ23587.1 - 0.0047 16.6 0.1 0.21 11.2 0.0 2.1 1 1 1 2 2 2 1 Thioredoxin Thioredoxin_8 PF13905.6 CBZ23587.1 - 0.014 15.7 0.1 0.31 11.4 0.1 2.1 1 1 1 2 2 2 0 Thioredoxin-like HyaE PF07449.11 CBZ23587.1 - 0.11 12.5 0.0 0.17 11.8 0.0 1.3 1 0 0 1 1 1 0 Hydrogenase-1 expression protein HyaE LPAM_1 PF08139.12 CBZ23587.1 - 0.59 10.7 4.3 1 10.0 4.3 1.4 1 0 0 1 1 1 0 Prokaryotic membrane lipoprotein lipid attachment site 2OG-FeII_Oxy_2 PF13532.6 CBZ23588.1 - 7.2e-08 32.9 0.0 1.7e-07 31.6 0.0 1.6 1 1 1 2 2 2 1 2OG-Fe(II) oxygenase superfamily TEX12 PF15219.6 CBZ23588.1 - 0.1 13.0 0.0 0.22 11.9 0.0 1.5 1 0 0 1 1 1 0 Testis-expressed 12 DeoC PF01791.9 CBZ23589.1 - 1.3e-13 51.2 5.4 1.7e-13 50.7 5.4 1.1 1 0 0 1 1 1 1 DeoC/LacD family aldolase PilX_N PF14341.6 CBZ23589.1 - 0.012 15.6 0.1 0.05 13.6 0.1 2.1 1 0 0 1 1 1 0 PilX N-terminal SNase PF00565.17 CBZ23590.1 - 1.7e-18 67.0 0.0 2.4e-18 66.6 0.0 1.2 1 0 0 1 1 1 1 Staphylococcal nuclease homologue Ada_Zn_binding PF02805.16 CBZ23590.1 - 0.019 14.9 0.6 0.054 13.5 0.6 1.8 1 1 0 1 1 1 0 Metal binding domain of Ada Erythro_esteras PF05139.14 CBZ23590.1 - 0.14 12.0 0.0 0.17 11.7 0.0 1.3 1 0 0 1 1 1 0 Erythromycin esterase DUF3450 PF11932.8 CBZ23591.1 - 0.0094 15.3 6.7 0.0094 15.3 6.7 4.1 2 1 0 3 3 3 2 Protein of unknown function (DUF3450) Surfac_D-trimer PF09006.11 CBZ23591.1 - 0.22 11.4 2.1 3.1 7.8 0.8 3.3 3 0 0 3 3 3 0 Lung surfactant protein D coiled-coil trimerisation OsmC PF02566.19 CBZ23591.1 - 0.72 10.4 4.0 0.75 10.3 0.3 2.7 2 1 0 2 2 2 0 OsmC-like protein GAS PF13851.6 CBZ23591.1 - 4.3 6.6 55.3 1.1 8.6 7.0 5.2 3 2 2 5 5 5 0 Growth-arrest specific micro-tubule binding CALCOCO1 PF07888.11 CBZ23591.1 - 6.3 5.5 49.0 0.041 12.7 24.1 3.1 2 1 1 3 3 3 0 Calcium binding and coiled-coil domain (CALCOCO1) like MAD PF05557.13 CBZ23591.1 - 9.2 4.5 48.3 0.81 8.0 21.0 3.2 2 1 1 3 3 3 0 Mitotic checkpoint protein TraC PF07820.12 CBZ23592.1 - 0.57 10.6 0.0 0.57 10.6 0.0 2.5 3 0 0 3 3 3 0 TraC-like protein CoaE PF01121.20 CBZ23593.1 - 0.63 9.7 2.5 0.75 9.4 1.1 1.8 2 0 0 2 2 2 0 Dephospho-CoA kinase PIG-X PF08320.12 CBZ23594.1 - 4.6e-06 26.7 0.0 9.9e-05 22.3 0.0 2.1 2 0 0 2 2 2 2 PIG-X / PBN1 WD40 PF00400.32 CBZ23595.1 - 2.7e-06 28.0 0.5 0.0081 17.0 0.2 4.6 4 1 0 4 4 4 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBZ23595.1 - 0.001 19.4 0.4 0.082 13.2 0.0 3.0 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain RTT107_BRCT_5 PF16770.5 CBZ23596.1 - 4e-05 23.4 0.0 8e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 Regulator of Ty1 transposition protein 107 BRCT domain BRCT_2 PF16589.5 CBZ23596.1 - 0.00029 21.2 0.0 0.00062 20.1 0.0 1.5 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain DisA_N PF02457.16 CBZ23596.1 - 0.11 12.1 0.4 0.29 10.7 0.4 1.7 1 0 0 1 1 1 0 DisA bacterial checkpoint controller nucleotide-binding DUF4379 PF14311.6 CBZ23597.1 - 5.2e-27 94.0 21.7 5.3e-09 36.3 0.4 4.7 4 0 0 4 4 4 3 Probable Zinc-ribbon domain HypA PF01155.19 CBZ23597.1 - 8.1e-05 22.6 16.4 0.057 13.4 0.0 4.6 3 2 0 4 4 4 2 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zinc_ribbon_9 PF14369.6 CBZ23597.1 - 3.8 7.8 16.6 7.8 6.8 3.0 5.0 4 0 0 4 4 4 0 zinc-ribbon NTF2 PF02136.20 CBZ23599.1 - 3.5e-16 59.8 0.0 4e-16 59.7 0.0 1.0 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain Pkinase PF00069.25 CBZ23600.1 - 2.5e-60 204.1 0.0 3.8e-37 128.1 0.0 2.0 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ23600.1 - 4e-32 111.5 0.0 3.7e-23 82.1 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.23 CBZ23600.1 - 3.5e-05 23.9 0.1 0.1 12.5 0.0 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kinase-like PF14531.6 CBZ23600.1 - 0.00074 18.9 0.0 0.0028 17.0 0.0 1.8 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 CBZ23600.1 - 0.0089 15.4 0.0 0.018 14.4 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 CBZ23600.1 - 0.058 12.3 0.0 0.084 11.8 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Pox_ser-thr_kin PF05445.11 CBZ23600.1 - 0.16 10.9 0.0 0.24 10.4 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Thioredoxin PF00085.20 CBZ23601.1 - 7.8e-11 41.9 0.0 9.5e-11 41.6 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin OST3_OST6 PF04756.13 CBZ23601.1 - 0.00084 18.8 0.0 0.0016 17.8 0.0 1.5 1 1 0 1 1 1 1 OST3 / OST6 family, transporter family zf-LSD1 PF06943.12 CBZ23602.1 - 0.1 12.4 0.1 1.4 8.8 0.0 2.7 2 0 0 2 2 2 0 LSD1 zinc finger SpdB PF05122.13 CBZ23604.1 - 0.018 15.2 0.4 0.62 10.2 0.2 3.0 2 0 0 2 2 2 0 Mobile element transfer protein PCO_ADO PF07847.12 CBZ23605.1 - 1.9e-53 180.9 0.0 2.5e-53 180.6 0.0 1.1 1 0 0 1 1 1 1 PCO_ADO CDO_I PF05995.12 CBZ23605.1 - 0.038 13.3 0.1 4.1 6.7 0.0 2.3 2 0 0 2 2 2 0 Cysteine dioxygenase type I Cupin_2 PF07883.11 CBZ23605.1 - 0.094 12.4 0.0 3.5 7.4 0.0 2.9 3 0 0 3 3 3 0 Cupin domain FAD_binding_3 PF01494.19 CBZ23606.1 - 7.6e-10 38.6 0.0 4.2e-09 36.1 0.0 2.1 1 1 0 1 1 1 1 FAD binding domain SE PF08491.10 CBZ23606.1 - 0.026 13.6 0.0 0.046 12.8 0.0 1.4 1 0 0 1 1 1 0 Squalene epoxidase EnY2 PF10163.9 CBZ23607.1 - 8.4e-07 29.3 0.0 1e-06 29.0 0.0 1.1 1 0 0 1 1 1 1 Transcription factor e(y)2 Phage_head_chap PF11113.8 CBZ23607.1 - 0.023 14.8 0.1 1 9.5 0.0 2.3 2 0 0 2 2 2 0 Head assembly gene product DUF2267 PF10025.9 CBZ23607.1 - 0.064 13.5 0.4 0.077 13.3 0.4 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2267) DUF3112 PF11309.8 CBZ23608.1 - 0.0046 16.4 1.1 0.0097 15.4 1.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3112) DFF-C PF09033.10 CBZ23608.1 - 0.37 10.7 3.3 0.69 9.8 3.3 1.4 1 0 0 1 1 1 0 DNA Fragmentation factor 45kDa, C terminal domain DUF4191 PF13829.6 CBZ23608.1 - 0.39 10.0 0.1 0.39 10.0 0.1 2.3 2 1 2 4 4 4 0 Domain of unknown function (DUF4191) FA_hydroxylase PF04116.13 CBZ23608.1 - 1 9.7 2.9 1.2 9.5 0.4 2.2 1 1 2 3 3 3 0 Fatty acid hydroxylase superfamily TAF4 PF05236.14 CBZ23608.1 - 1.7 8.3 6.4 2.6 7.7 6.4 1.2 1 0 0 1 1 1 0 Transcription initiation factor TFIID component TAF4 family BT1 PF03092.16 CBZ23609.1 - 1.2e-189 630.9 10.2 1.4e-189 630.7 10.2 1.0 1 0 0 1 1 1 1 BT1 family MFS_1 PF07690.16 CBZ23609.1 - 0.051 12.5 43.0 0.055 12.4 8.2 3.4 1 1 1 2 2 2 0 Major Facilitator Superfamily Coprogen_oxidas PF01218.18 CBZ23610.1 - 1.3e-130 434.4 0.0 1.5e-130 434.2 0.0 1.0 1 0 0 1 1 1 1 Coproporphyrinogen III oxidase Flavodoxin_5 PF12724.7 CBZ23611.1 - 3.4e-48 163.6 0.1 4.3e-48 163.2 0.1 1.1 1 0 0 1 1 1 1 Flavodoxin domain Flavodoxin_3 PF12641.7 CBZ23611.1 - 0.0045 16.7 0.0 0.0073 16.0 0.0 1.3 1 0 0 1 1 1 1 Flavodoxin domain Flavodoxin_1 PF00258.25 CBZ23611.1 - 0.026 14.7 0.1 0.036 14.3 0.1 1.3 1 0 0 1 1 1 0 Flavodoxin Peptidase_S46 PF10459.9 CBZ23611.1 - 0.18 10.4 0.0 0.24 10.0 0.0 1.1 1 0 0 1 1 1 0 Peptidase S46 Cyt-b5 PF00173.28 CBZ23612.1 - 6.2e-07 29.5 0.0 6.5e-07 29.4 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain DUF1583 PF07622.11 CBZ23612.1 - 0.033 12.9 0.1 0.058 12.2 0.1 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1583) ThiF PF00899.21 CBZ23613.1 - 1.9e-38 132.2 0.0 3.1e-38 131.5 0.0 1.3 1 0 0 1 1 1 1 ThiF family ATG7_N PF16420.5 CBZ23613.1 - 5.3e-26 92.0 0.0 7.4e-26 91.5 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-like modifier-activating enzyme ATG7 N-terminus Shikimate_DH PF01488.20 CBZ23613.1 - 4.4e-05 23.6 0.1 0.0043 17.1 0.0 2.3 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase 2-Hacid_dh_C PF02826.19 CBZ23613.1 - 0.051 12.9 0.0 13 5.1 0.0 2.4 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain KR PF08659.10 CBZ23613.1 - 0.67 9.8 2.2 17 5.2 0.1 2.8 2 1 0 2 2 2 0 KR domain Isy1 PF06246.12 CBZ23614.1 - 9.2e-27 94.2 11.8 7.1e-26 91.3 11.8 2.3 1 1 0 1 1 1 1 Isy1-like splicing family DOT1 PF08123.13 CBZ23615.1 - 1.5e-21 76.9 0.0 2.5e-21 76.2 0.0 1.3 1 0 0 1 1 1 1 Histone methylation protein DOT1 Methyltransf_31 PF13847.6 CBZ23615.1 - 1.6e-05 24.8 0.0 2.4e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CBZ23615.1 - 2.7e-05 24.8 0.0 5.7e-05 23.7 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CBZ23615.1 - 0.0005 20.7 0.0 0.0011 19.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.6 CBZ23615.1 - 0.00078 19.5 0.0 0.0013 18.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 CBZ23615.1 - 0.0063 15.8 0.0 0.01 15.1 0.0 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_12 PF08242.12 CBZ23615.1 - 0.028 15.2 0.0 0.045 14.5 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain DUF4268 PF14088.6 CBZ23615.1 - 0.032 14.1 0.0 0.056 13.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4268) Methyltransf_23 PF13489.6 CBZ23615.1 - 0.047 13.5 0.0 0.066 13.0 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain AdoMet_MTase PF07757.13 CBZ23615.1 - 0.068 13.5 0.0 0.11 12.8 0.0 1.4 1 0 0 1 1 1 0 Predicted AdoMet-dependent methyltransferase MTS PF05175.14 CBZ23615.1 - 0.15 11.6 0.0 0.25 10.9 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Adaptin_N PF01602.20 CBZ23618.1 - 2.7e-86 290.2 9.7 3.4e-86 289.9 9.7 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 CBZ23618.1 - 0.00081 19.5 2.0 0.066 13.2 0.0 2.7 2 1 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 CBZ23618.1 - 0.014 15.6 0.1 0.19 12.1 0.1 3.0 2 0 0 2 2 2 0 HEAT repeat HEAT_2 PF13646.6 CBZ23618.1 - 0.019 15.4 0.2 3.5 8.1 0.0 3.6 4 0 0 4 4 4 0 HEAT repeats DUF5315 PF17242.2 CBZ23618.1 - 0.019 14.8 0.0 0.053 13.4 0.0 1.7 1 0 0 1 1 1 0 Disordered region of unknown function (DUF5315) Nipped-B_C PF12830.7 CBZ23618.1 - 0.15 12.0 3.3 0.52 10.2 0.1 3.0 3 0 0 3 3 3 0 Sister chromatid cohesion C-terminus Cytochrom_C1 PF02167.15 CBZ23619.1 - 1.1e-76 257.4 0.0 1.3e-76 257.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome C1 family Met_synt_B12 PF02965.17 CBZ23622.1 - 1.1e-104 349.8 0.1 2.2e-104 348.7 0.1 1.6 1 0 0 1 1 1 1 Vitamin B12 dependent methionine synthase, activation domain S-methyl_trans PF02574.16 CBZ23622.1 - 1.7e-75 254.3 0.1 6.5e-75 252.4 0.0 2.0 2 0 0 2 2 2 1 Homocysteine S-methyltransferase Pterin_bind PF00809.22 CBZ23622.1 - 5e-46 157.4 0.2 8.6e-45 153.3 0.1 2.4 2 0 0 2 2 2 1 Pterin binding enzyme B12-binding_2 PF02607.17 CBZ23622.1 - 1.3e-24 86.4 0.6 5.1e-24 84.5 0.1 2.4 2 0 0 2 2 2 1 B12 binding domain B12-binding PF02310.19 CBZ23622.1 - 3.4e-21 75.5 0.4 3.9e-20 72.1 0.4 2.7 3 0 0 3 3 3 1 B12 binding domain OKR_DC_1_N PF03709.15 CBZ23622.1 - 0.087 13.1 0.0 1.5 9.2 0.0 2.6 2 0 0 2 2 2 0 Orn/Lys/Arg decarboxylase, N-terminal domain DUF4973 PF16343.5 CBZ23622.1 - 0.16 12.1 0.0 0.61 10.1 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4973) GAIN PF16489.5 CBZ23622.1 - 0.16 11.4 0.0 0.36 10.2 0.0 1.5 1 0 0 1 1 1 0 GPCR-Autoproteolysis INducing (GAIN) domain M16C_assoc PF08367.11 CBZ23623.1 - 1.5e-26 93.1 0.3 5.6e-26 91.2 0.0 2.0 2 0 0 2 2 2 1 Peptidase M16C associated Peptidase_M16_C PF05193.21 CBZ23623.1 - 3.2e-23 82.7 0.0 1.8e-15 57.4 0.0 2.6 2 0 0 2 2 2 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 CBZ23623.1 - 9.9e-16 58.1 0.1 6.7e-12 45.6 0.0 2.7 2 0 0 2 2 2 2 Insulinase (Peptidase family M16) DUF1542 PF07564.11 CBZ23623.1 - 2.5 8.3 5.9 2.1 8.5 1.5 2.4 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1542) EF-hand_1 PF00036.32 CBZ23624.1 - 4.1e-24 82.3 4.1 8.4e-07 28.1 0.1 5.0 5 0 0 5 5 5 4 EF hand EF-hand_7 PF13499.6 CBZ23624.1 - 1.3e-21 76.9 0.0 7.7e-06 26.3 0.0 4.2 4 0 0 4 4 4 4 EF-hand domain pair EF-hand_6 PF13405.6 CBZ23624.1 - 3.4e-21 73.3 0.8 9e-05 22.1 0.1 5.5 6 0 0 6 6 6 4 EF-hand domain EF-hand_8 PF13833.6 CBZ23624.1 - 1.9e-18 66.1 0.6 0.0001 22.1 0.1 4.5 4 1 0 4 4 4 3 EF-hand domain pair EF-hand_5 PF13202.6 CBZ23624.1 - 1.1e-15 56.4 3.6 7e-06 25.3 0.0 4.5 4 0 0 4 4 4 4 EF hand EF-hand_4 PF12763.7 CBZ23624.1 - 0.0026 17.7 0.0 4.1 7.4 0.0 3.2 2 1 1 3 3 3 2 Cytoskeletal-regulatory complex EF hand EF-hand_11 PF08976.11 CBZ23624.1 - 0.018 15.9 0.2 2.4 9.1 0.1 3.4 3 1 1 4 4 4 0 EF-hand domain SPARC_Ca_bdg PF10591.9 CBZ23624.1 - 0.018 15.3 0.0 3.1 8.1 0.0 3.0 3 0 0 3 3 3 0 Secreted protein acidic and rich in cysteine Ca binding region DUF2709 PF10915.8 CBZ23624.1 - 0.035 13.4 0.0 0.056 12.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2709) EF-hand_9 PF14658.6 CBZ23624.1 - 0.091 13.1 1.0 5.4 7.4 0.0 3.4 4 0 0 4 4 4 0 EF-hand domain Sec7 PF01369.20 CBZ23625.1 - 2.3e-36 125.2 0.0 4.2e-36 124.3 0.0 1.5 1 0 0 1 1 1 1 Sec7 domain tRNA_Me_trans PF03054.16 CBZ23626.1 - 5.9e-41 140.4 0.1 5e-27 94.6 0.0 4.5 5 0 0 5 5 5 4 tRNA methyl transferase Asn_synthase PF00733.21 CBZ23626.1 - 0.026 14.2 0.1 0.05 13.3 0.1 1.4 1 0 0 1 1 1 0 Asparagine synthase NAD_synthase PF02540.17 CBZ23626.1 - 0.031 13.4 0.1 0.056 12.5 0.1 1.3 1 0 0 1 1 1 0 NAD synthase DUF1751 PF08551.10 CBZ23627.1 - 0.0066 17.0 0.7 0.021 15.4 0.2 2.1 1 1 1 2 2 2 1 Eukaryotic integral membrane protein (DUF1751) Rhomboid PF01694.22 CBZ23627.1 - 0.054 13.5 1.7 0.63 10.0 0.1 2.3 2 0 0 2 2 2 0 Rhomboid family Med3 PF11593.8 CBZ23627.1 - 0.62 9.2 5.2 0.89 8.7 5.2 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal DUF747 PF05346.11 CBZ23628.1 - 5.5e-72 242.9 4.0 7.6e-72 242.5 4.0 1.1 1 0 0 1 1 1 1 Eukaryotic membrane protein family Pkinase PF00069.25 CBZ23629.1 - 1.1e-48 165.9 0.0 1.9e-48 165.1 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ23629.1 - 6.3e-31 107.6 0.0 1.2e-30 106.7 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CBZ23629.1 - 9.2e-06 25.2 0.0 1.6e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 Kinase-like YrbL-PhoP_reg PF10707.9 CBZ23629.1 - 0.12 11.9 0.0 0.12 11.9 0.0 1.7 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL APH PF01636.23 CBZ23629.1 - 0.24 11.3 0.0 0.24 11.3 0.0 3.1 3 1 0 3 3 3 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 CBZ23629.1 - 0.31 9.8 0.0 0.31 9.8 0.0 2.0 2 0 0 2 2 2 0 Fungal protein kinase Pkinase PF00069.25 CBZ23630.1 - 4.2e-49 167.3 0.0 6.4e-29 101.1 0.1 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ23630.1 - 5.1e-34 117.7 0.0 7.2e-20 71.4 0.2 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 CBZ23630.1 - 0.0017 17.7 0.1 0.11 11.7 0.1 2.2 2 0 0 2 2 2 1 Kinase-like CinA PF02464.17 CBZ23630.1 - 0.022 14.3 0.1 0.053 13.1 0.1 1.6 1 0 0 1 1 1 0 Competence-damaged protein Pkinase_fungal PF17667.1 CBZ23630.1 - 0.026 13.3 0.0 0.054 12.3 0.0 1.5 1 0 0 1 1 1 0 Fungal protein kinase Kdo PF06293.14 CBZ23630.1 - 0.048 13.0 3.1 0.15 11.4 0.2 2.6 3 0 0 3 3 3 0 Lipopolysaccharide kinase (Kdo/WaaP) family PTPA PF03095.15 CBZ23632.1 - 8.1e-96 321.0 0.0 1e-95 320.7 0.0 1.1 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein PLDc_2 PF13091.6 CBZ23633.1 - 4.7e-09 36.2 0.0 0.00024 21.0 0.0 3.3 3 0 0 3 3 3 2 PLD-like domain PLDc PF00614.22 CBZ23633.1 - 1.2e-06 28.4 0.6 1.8e-05 24.7 0.1 2.8 2 1 0 2 2 2 1 Phospholipase D Active site motif HNF_C PF09354.10 CBZ23633.1 - 0.013 16.6 0.0 0.046 14.8 0.0 2.0 1 0 0 1 1 1 0 HNF3 C-terminal domain CIAPIN1 PF05093.13 CBZ23636.1 - 1.6e-14 54.3 17.0 7.5e-11 42.4 4.4 2.2 1 1 1 2 2 2 2 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis Pkinase PF00069.25 CBZ23638.1 - 2.7e-35 122.0 0.0 1.1e-13 51.2 0.0 3.8 3 1 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ23638.1 - 4.7e-16 58.8 0.0 1e-10 41.3 0.0 2.4 2 1 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 CBZ23638.1 - 0.14 11.4 0.0 0.38 10.0 0.0 1.6 1 0 0 1 1 1 0 Kinase-like Homoserine_dh PF00742.19 CBZ23639.1 - 2.4e-53 180.6 0.0 3.3e-53 180.2 0.0 1.2 1 0 0 1 1 1 1 Homoserine dehydrogenase NAD_binding_3 PF03447.16 CBZ23639.1 - 4.2e-09 37.1 0.1 8.1e-09 36.2 0.1 1.4 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain TetR_C_24 PF17932.1 CBZ23639.1 - 0.035 14.4 0.0 1.5 9.1 0.0 2.5 1 1 1 2 2 2 0 Tetracyclin repressor-like, C-terminal domain Peptidase_M20 PF01546.28 CBZ23640.1 - 4e-34 118.1 0.0 6e-34 117.6 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 CBZ23640.1 - 4.7e-19 68.3 0.0 7.7e-19 67.6 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain PEP_mutase PF13714.6 CBZ23640.1 - 0.15 11.5 0.0 0.33 10.4 0.0 1.5 1 0 0 1 1 1 0 Phosphoenolpyruvate phosphomutase HECT PF00632.25 CBZ23641.1 - 3.1e-87 292.9 0.0 4.6e-87 292.4 0.0 1.3 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) C1_2 PF03107.16 CBZ23641.1 - 2.4e-05 24.5 7.3 5e-05 23.5 7.3 1.6 1 0 0 1 1 1 1 C1 domain ZZ PF00569.17 CBZ23641.1 - 0.015 15.1 8.7 0.033 14.0 8.7 1.5 1 0 0 1 1 1 0 Zinc finger, ZZ type Coilin_N PF15862.5 CBZ23641.1 - 0.14 12.0 4.1 0.38 10.5 4.1 1.7 1 0 0 1 1 1 0 Coilin N-terminus YabA PF06156.13 CBZ23641.1 - 1.4 9.6 7.2 33 5.2 0.0 2.7 2 0 0 2 2 2 0 Initiation control protein YabA TERB2 PF15101.6 CBZ23641.1 - 1.8 8.6 7.8 4.9 7.1 7.8 1.7 1 0 0 1 1 1 0 Telomere-associated protein TERB2 Peptidase_S49_N PF08496.10 CBZ23641.1 - 4.5 7.3 6.8 12 6.0 6.8 1.6 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Spt20 PF12090.8 CBZ23641.1 - 6.1 6.4 14.4 27 4.3 14.4 2.1 1 0 0 1 1 1 0 Spt20 family UPF0172 PF03665.13 CBZ23642.1 - 1.5e-49 168.7 0.0 1.7e-49 168.4 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0172) LRR_4 PF12799.7 CBZ23643.1 - 0.00031 21.1 2.6 0.0015 18.8 2.5 2.0 1 1 1 2 2 2 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CBZ23643.1 - 0.006 16.3 1.1 0.015 15.0 1.1 1.7 1 0 0 1 1 1 1 Leucine rich repeat Flagellar_rod PF05149.12 CBZ23644.1 - 9e-12 45.0 14.2 9e-12 45.0 14.2 2.1 2 0 0 2 2 2 1 Paraflagellar rod protein ABA_GPCR PF12430.8 CBZ23646.1 - 1e-31 110.1 1.8 1e-31 110.1 1.8 1.8 2 0 0 2 2 2 1 Abscisic acid G-protein coupled receptor GPHR_N PF12537.8 CBZ23646.1 - 1.8e-07 31.1 0.0 6.4e-07 29.4 0.0 2.0 1 0 0 1 1 1 1 The Golgi pH Regulator (GPHR) Family N-terminal DUF3535 PF12054.8 CBZ23646.1 - 0.086 12.1 0.0 0.14 11.4 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3535) Pilin_N PF07790.11 CBZ23646.1 - 0.18 12.8 2.6 1 10.3 0.0 2.9 2 0 0 2 2 2 0 Archaeal Type IV pilin, N-terminal Lentivirus_VIF PF05851.11 CBZ23646.1 - 0.2 10.5 0.0 0.48 9.3 0.0 1.6 2 0 0 2 2 2 0 Lentivirus virion infectivity factor (VIF) NUDIX PF00293.28 CBZ23647.1 - 2.8e-10 40.3 0.0 5.8e-10 39.3 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain DEAD PF00270.29 CBZ23648.1 - 1e-45 155.7 0.0 2e-45 154.7 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CBZ23648.1 - 1.3e-24 86.7 0.0 1.1e-23 83.7 0.1 2.3 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 CBZ23648.1 - 0.0029 17.6 0.0 0.012 15.6 0.0 1.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_C_2 PF13307.6 CBZ23648.1 - 0.032 14.4 0.0 0.056 13.6 0.0 1.3 1 0 0 1 1 1 0 Helicase C-terminal domain CMS1 PF14617.6 CBZ23648.1 - 0.085 12.2 0.0 0.18 11.1 0.0 1.5 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit DUF1179 PF06678.11 CBZ23649.1 - 0.64 10.0 3.4 1.2 9.2 0.3 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1179) DUF1674 PF07896.12 CBZ23650.1 - 9.8e-15 54.8 0.1 1.3e-14 54.3 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1674) zf-C3HC4 PF00097.25 CBZ23651.1 - 9.9e-08 31.7 6.8 2.3e-07 30.6 6.8 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CBZ23651.1 - 1.4e-07 31.4 6.5 3.8e-07 30.0 6.5 1.8 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 CBZ23651.1 - 3.6e-07 29.9 5.7 1.1e-06 28.4 5.7 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 CBZ23651.1 - 4.8e-07 29.5 7.8 1.5e-06 27.9 7.8 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 CBZ23651.1 - 1.5e-06 28.2 5.9 4e-06 26.9 5.9 1.8 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.6 CBZ23651.1 - 2.4e-06 27.8 7.5 2.4e-06 27.8 7.5 2.4 2 0 0 2 2 2 1 Ring finger domain Prok-RING_4 PF14447.6 CBZ23651.1 - 1.6e-05 24.7 6.3 4.5e-05 23.2 6.3 1.8 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-rbx1 PF12678.7 CBZ23651.1 - 0.00021 21.5 4.7 0.00087 19.5 4.7 2.1 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 CBZ23651.1 - 0.00024 21.0 7.0 0.0006 19.7 7.0 1.8 1 0 0 1 1 1 1 zinc-RING finger domain zf-TRAF PF02176.18 CBZ23651.1 - 0.00087 19.9 0.4 0.0028 18.3 0.4 1.9 1 0 0 1 1 1 1 TRAF-type zinc finger Sina PF03145.16 CBZ23651.1 - 0.009 16.0 0.4 0.015 15.2 0.4 1.3 1 0 0 1 1 1 1 Seven in absentia protein family zf-Nse PF11789.8 CBZ23651.1 - 0.012 15.4 1.6 0.056 13.3 1.6 2.1 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit U-box PF04564.15 CBZ23651.1 - 0.02 15.0 0.0 0.11 12.6 0.0 2.3 2 0 0 2 2 2 0 U-box domain Podoplanin PF05808.11 CBZ23651.1 - 0.068 13.3 0.2 0.51 10.4 0.0 2.4 2 0 0 2 2 2 0 Podoplanin zf-RING_6 PF14835.6 CBZ23651.1 - 0.087 12.7 1.8 0.22 11.4 1.8 1.7 1 0 0 1 1 1 0 zf-RING of BARD1-type protein IBR PF01485.21 CBZ23651.1 - 0.39 11.0 4.2 0.19 12.0 1.2 2.0 2 0 0 2 2 2 0 IBR domain, a half RING-finger domain zf-RING_10 PF16685.5 CBZ23651.1 - 1.2 9.3 6.5 2.9 8.1 6.5 1.6 1 0 0 1 1 1 0 zinc RING finger of MSL2 zf-ANAPC11 PF12861.7 CBZ23651.1 - 9.2 6.4 10.6 1.2 9.2 4.4 2.7 2 1 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger Rav1p_C PF12234.8 CBZ23652.1 - 3.7e-40 138.0 0.0 2.6e-27 95.5 0.8 3.1 2 1 0 2 2 2 2 RAVE protein 1 C terminal RT_RNaseH_2 PF17919.1 CBZ23652.1 - 0.1 12.7 0.1 0.32 11.1 0.1 1.8 1 0 0 1 1 1 0 RNase H-like domain found in reverse transcriptase EamA PF00892.20 CBZ23654.1 - 8e-15 55.2 27.1 3.1e-08 33.9 0.5 3.2 3 0 0 3 3 3 3 EamA-like transporter family PUNUT PF16913.5 CBZ23654.1 - 0.00017 21.0 4.3 0.00037 19.8 4.3 1.6 1 1 0 1 1 1 1 Purine nucleobase transmembrane transport SLC35F PF06027.12 CBZ23654.1 - 0.00059 19.4 3.7 0.00059 19.4 3.7 1.6 2 0 0 2 2 2 1 Solute carrier family 35 TPT PF03151.16 CBZ23654.1 - 0.00098 18.6 1.5 0.0017 17.7 1.5 1.3 1 0 0 1 1 1 1 Triose-phosphate Transporter family DUF3955 PF13127.6 CBZ23654.1 - 0.21 11.4 2.6 0.72 9.7 2.6 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3955) SIN1_PH PF16979.5 CBZ23655.1 - 1.4e-08 35.0 0.3 2.5e-08 34.2 0.3 1.4 1 0 0 1 1 1 1 SAPK-interacting protein 1 (Sin1), Pleckstrin-homology Ring_hydroxyl_A PF00848.19 CBZ23655.1 - 0.042 13.8 0.1 0.67 9.9 0.0 2.3 2 0 0 2 2 2 0 Ring hydroxylating alpha subunit (catalytic domain) MaoC_dehydratas PF01575.19 CBZ23657.1 - 4.2e-23 81.2 0.0 6.5e-23 80.6 0.0 1.3 1 0 0 1 1 1 1 MaoC like domain MaoC_dehydrat_N PF13452.6 CBZ23657.1 - 2.6e-10 40.5 0.0 4.1e-10 39.9 0.0 1.3 1 0 0 1 1 1 1 N-terminal half of MaoC dehydratase 4HBT PF03061.22 CBZ23657.1 - 0.1 13.0 0.0 0.26 11.7 0.0 1.7 2 0 0 2 2 2 0 Thioesterase superfamily MaoC_dehydratas PF01575.19 CBZ23658.1 - 2.8e-21 75.3 0.0 3.8e-21 74.9 0.0 1.1 1 0 0 1 1 1 1 MaoC like domain MaoC_dehydrat_N PF13452.6 CBZ23658.1 - 3.2e-13 50.0 0.0 6.9e-13 48.9 0.0 1.6 1 1 1 2 2 2 1 N-terminal half of MaoC dehydratase 4HBT PF03061.22 CBZ23658.1 - 0.00091 19.5 0.0 0.0016 18.8 0.0 1.4 1 0 0 1 1 1 1 Thioesterase superfamily 4HBT_2 PF13279.6 CBZ23658.1 - 0.052 14.0 0.0 0.055 13.9 0.0 1.3 1 0 0 1 1 1 0 Thioesterase-like superfamily Acyl-CoA_dh_N PF02771.16 CBZ23660.1 - 4e-10 40.3 0.0 9.4e-10 39.2 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 CBZ23660.1 - 2.6e-05 24.3 0.1 8.4e-05 22.7 0.1 1.9 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Fascin PF06268.13 CBZ23660.1 - 0.067 13.4 0.0 0.18 12.0 0.0 1.7 1 0 0 1 1 1 0 Fascin domain RIBIOP_C PF04950.12 CBZ23661.1 - 3.2e-92 309.1 0.0 5.9e-92 308.2 0.0 1.5 1 0 0 1 1 1 1 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal AARP2CN PF08142.12 CBZ23661.1 - 3.1e-15 56.0 0.0 9.1e-15 54.5 0.0 1.8 1 0 0 1 1 1 1 AARP2CN (NUC121) domain MATalpha_HMGbox PF04769.12 CBZ23661.1 - 0.022 14.1 0.0 0.045 13.0 0.0 1.4 1 0 0 1 1 1 0 Mating-type protein MAT alpha 1 HMG-box DUF5018 PF16410.5 CBZ23661.1 - 0.082 11.6 0.1 0.14 10.9 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5018) DHC_N2 PF08393.13 CBZ23663.1 - 3e-40 138.6 0.0 6.4e-40 137.5 0.0 1.6 1 0 0 1 1 1 1 Dynein heavy chain, N-terminal region 2 AAA_7 PF12775.7 CBZ23663.1 - 1.9e-05 24.3 0.0 0.00033 20.2 0.0 2.3 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_8 PF12780.7 CBZ23663.1 - 0.00039 19.8 0.0 0.0009 18.6 0.0 1.5 1 0 0 1 1 1 1 P-loop containing dynein motor region D4 AAA_6 PF12774.7 CBZ23663.1 - 0.056 12.4 0.0 0.19 10.6 0.0 1.7 2 0 0 2 2 2 0 Hydrolytic ATP binding site of dynein motor region Exonuc_VII_L PF02601.15 CBZ23663.1 - 3.8 7.0 8.0 2.4 7.6 5.4 2.0 2 0 0 2 2 2 0 Exonuclease VII, large subunit DUF1180 PF06679.12 CBZ23664.1 - 0.02 15.3 3.9 0.02 15.3 3.9 3.0 3 1 0 3 3 3 0 Protein of unknown function (DUF1180) DUF4611 PF15387.6 CBZ23664.1 - 0.09 13.0 3.3 0.2 11.9 3.3 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) NOA36 PF06524.12 CBZ23664.1 - 4.3 6.6 5.1 7.7 5.7 5.1 1.3 1 0 0 1 1 1 0 NOA36 protein Cwf_Cwc_15 PF04889.12 CBZ23664.1 - 8.5 6.0 11.9 1 9.0 4.9 2.1 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein Ribosomal_L7Ae PF01248.26 CBZ23665.1 - 2.9e-20 71.8 0.3 5.8e-20 70.8 0.3 1.5 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RNase_P_pop3 PF08228.11 CBZ23665.1 - 0.00014 22.0 0.1 0.00021 21.4 0.1 1.3 1 0 0 1 1 1 1 RNase P subunit Pop3 Ribosomal_L7Ae PF01248.26 CBZ23666.1 - 3.4e-20 71.6 0.3 7.4e-20 70.5 0.3 1.6 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RNase_P_pop3 PF08228.11 CBZ23666.1 - 0.00018 21.6 0.1 0.00028 21.0 0.1 1.3 1 0 0 1 1 1 1 RNase P subunit Pop3 Sec20 PF03908.13 CBZ23667.1 - 0.00022 21.1 0.8 0.00059 19.7 0.7 1.9 1 1 0 1 1 1 1 Sec20 V-SNARE_C PF12352.8 CBZ23667.1 - 0.013 15.7 1.6 0.033 14.5 1.6 1.6 1 0 0 1 1 1 0 Snare region anchored in the vesicle membrane C-terminus Cytochrom_B562 PF07361.11 CBZ23667.1 - 0.29 11.8 4.9 0.12 13.1 1.2 2.1 2 1 0 2 2 2 0 Cytochrome b562 DcrB PF08786.11 CBZ23667.1 - 0.35 11.0 3.5 0.37 10.9 0.2 2.1 2 0 0 2 2 2 0 DcrB Snapin_Pallidin PF14712.6 CBZ23667.1 - 0.35 11.3 6.2 0.2 12.1 2.5 2.2 2 1 0 2 2 2 0 Snapin/Pallidin DUF5345 PF17280.2 CBZ23667.1 - 0.36 10.8 1.8 0.83 9.7 0.4 2.3 1 1 1 2 2 2 0 Family of unknown function (DUF5345) CCDC-167 PF15188.6 CBZ23667.1 - 0.59 10.5 5.9 0.98 9.8 0.3 2.7 2 1 0 2 2 2 0 Coiled-coil domain-containing protein 167 DUF4349 PF14257.6 CBZ23667.1 - 0.72 9.3 8.3 1.7 8.1 1.8 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4349) TSNAXIP1_N PF15739.5 CBZ23667.1 - 3.6 8.0 8.9 9.8 6.6 3.7 2.4 2 0 0 2 2 2 0 Translin-associated factor X-interacting N-terminus KxDL PF10241.9 CBZ23667.1 - 8.4 6.8 8.8 3.7 7.9 5.1 2.3 2 1 0 2 2 2 0 Uncharacterized conserved protein Mito_carr PF00153.27 CBZ23668.1 - 9.5e-32 108.8 4.8 9.9e-13 47.8 0.3 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein Arm_vescicular PF18770.1 CBZ23668.1 - 0.045 13.7 0.1 0.12 12.4 0.1 1.7 1 0 0 1 1 1 0 Armadillo tether-repeat of vescicular transport factor Ras PF00071.22 CBZ23671.1 - 8.8e-55 184.7 0.0 1e-54 184.5 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CBZ23671.1 - 3.9e-29 101.3 0.0 5.4e-29 100.8 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CBZ23671.1 - 1e-10 41.4 0.0 1.3e-10 41.0 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 CBZ23671.1 - 0.00044 20.3 0.0 0.00079 19.5 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 CBZ23671.1 - 0.00066 19.3 0.0 0.016 14.8 0.0 2.1 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 CBZ23671.1 - 0.0095 15.3 0.0 0.012 15.0 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region CLP1_P PF16575.5 CBZ23673.1 - 7.6e-28 97.6 0.0 2.3e-27 96.0 0.0 1.8 2 0 0 2 2 2 1 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_16 PF13191.6 CBZ23673.1 - 0.024 15.0 0.8 0.072 13.5 0.1 2.3 2 0 0 2 2 2 0 AAA ATPase domain MMR_HSR1 PF01926.23 CBZ23673.1 - 0.18 11.9 0.1 0.42 10.7 0.1 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase Sel1 PF08238.12 CBZ23674.1 - 8.1e-23 80.4 30.4 7.4e-08 32.8 0.0 8.5 8 0 0 8 8 8 6 Sel1 repeat ETF_QO PF05187.13 CBZ23675.1 - 3.4e-43 146.0 0.2 6.1e-43 145.2 0.2 1.4 1 0 0 1 1 1 1 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S FAD_binding_2 PF00890.24 CBZ23675.1 - 1.9e-08 33.8 2.5 0.00058 19.0 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.24 CBZ23675.1 - 4.7e-08 33.0 2.9 0.00029 20.5 1.3 2.2 1 1 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 CBZ23675.1 - 1.7e-06 28.2 0.3 6.7e-06 26.3 0.3 2.1 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 CBZ23675.1 - 9.2e-06 25.1 0.1 0.016 14.4 0.2 2.2 2 0 0 2 2 2 2 Thi4 family NAD_binding_9 PF13454.6 CBZ23675.1 - 6.5e-05 23.0 0.1 0.00013 22.0 0.1 1.5 1 0 0 1 1 1 1 FAD-NAD(P)-binding Pyr_redox PF00070.27 CBZ23675.1 - 8.3e-05 23.1 0.1 0.3 11.7 0.2 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 CBZ23675.1 - 0.00027 20.3 0.1 0.00048 19.5 0.1 1.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 CBZ23675.1 - 0.0049 15.6 0.3 0.0074 15.0 0.3 1.2 1 0 0 1 1 1 1 HI0933-like protein Trp_halogenase PF04820.14 CBZ23675.1 - 0.0096 14.8 0.4 0.089 11.6 0.2 2.0 2 0 0 2 2 2 1 Tryptophan halogenase FAD_binding_3 PF01494.19 CBZ23675.1 - 0.027 13.7 1.0 0.036 13.3 0.1 1.6 2 0 0 2 2 2 0 FAD binding domain Pyr_redox_3 PF13738.6 CBZ23675.1 - 0.03 13.6 0.1 0.042 13.1 0.1 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 CBZ23675.1 - 0.05 12.6 0.1 0.071 12.1 0.1 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein FAD_oxidored PF12831.7 CBZ23675.1 - 0.11 11.8 0.3 0.15 11.4 0.3 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase NPL PF17800.1 CBZ23676.1 - 3.5e-11 43.6 0.0 7e-11 42.6 0.0 1.5 1 1 0 1 1 1 1 Nucleoplasmin-like domain Pox_A_type_inc PF04508.12 CBZ23678.1 - 5.4e-05 22.9 1.1 0.089 12.7 0.0 3.8 4 0 0 4 4 3 1 Viral A-type inclusion protein repeat KASH_CCD PF14662.6 CBZ23678.1 - 0.0019 18.1 11.9 0.0019 18.1 11.9 2.7 3 0 0 3 3 3 1 Coiled-coil region of CCDC155 or KASH AAA_13 PF13166.6 CBZ23678.1 - 0.05 12.2 13.8 0.069 11.8 13.8 1.1 1 0 0 1 1 1 0 AAA domain SHE3 PF17078.5 CBZ23678.1 - 0.061 13.0 4.8 0.14 11.9 3.7 1.9 1 1 1 2 2 2 0 SWI5-dependent HO expression protein 3 Phage_GP20 PF06810.11 CBZ23678.1 - 0.2 11.5 14.0 0.086 12.6 7.4 2.6 1 1 1 2 2 2 0 Phage minor structural protein GP20 PRKG1_interact PF15898.5 CBZ23678.1 - 0.28 12.1 23.6 2.3 9.1 4.0 4.7 3 1 1 4 4 3 0 cGMP-dependent protein kinase interacting domain HALZ PF02183.18 CBZ23678.1 - 0.52 10.6 11.1 24 5.3 0.5 4.8 4 0 0 4 4 4 0 Homeobox associated leucine zipper DUF2730 PF10805.8 CBZ23678.1 - 0.54 10.4 4.8 1.9 8.6 0.3 3.2 1 1 2 3 3 3 0 Protein of unknown function (DUF2730) Fez1 PF06818.15 CBZ23678.1 - 0.61 10.5 22.2 0.18 12.2 16.8 2.7 2 1 1 3 3 3 0 Fez1 Fungal_TACC PF12709.7 CBZ23678.1 - 0.98 9.9 11.6 2.6 8.6 0.2 4.1 5 1 1 6 6 4 0 Fungal Transforming acidic coiled-coil (TACC) proteins Snapin_Pallidin PF14712.6 CBZ23678.1 - 1.2 9.6 5.5 2.3 8.7 0.5 3.2 1 1 2 3 3 3 0 Snapin/Pallidin Cytochrom_B562 PF07361.11 CBZ23678.1 - 1.3 9.7 13.3 0.91 10.2 1.7 3.3 2 1 2 4 4 3 0 Cytochrome b562 FAM184 PF15665.5 CBZ23678.1 - 1.8 8.3 23.0 4.2 7.1 22.4 2.1 1 1 0 1 1 1 0 Family with sequence similarity 184, A and B GAS PF13851.6 CBZ23678.1 - 2 7.7 15.6 7.2 5.9 11.4 2.4 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding YabA PF06156.13 CBZ23678.1 - 2.4 8.9 12.3 10 6.8 0.2 4.4 3 1 2 5 5 5 0 Initiation control protein YabA Cnn_1N PF07989.11 CBZ23678.1 - 2.5 8.3 13.8 1.5 9.0 0.4 3.2 4 0 0 4 4 2 0 Centrosomin N-terminal motif 1 DUF5082 PF16888.5 CBZ23678.1 - 3.2 8.1 10.7 25 5.2 0.8 3.5 1 1 1 2 2 2 0 Domain of unknown function (DUF5082) Bcr-Abl_Oligo PF09036.10 CBZ23678.1 - 3.8 7.6 5.6 9 6.4 0.1 3.7 3 1 1 4 4 4 0 Bcr-Abl oncoprotein oligomerisation domain FAM76 PF16046.5 CBZ23678.1 - 3.8 6.8 8.7 4.5 6.5 7.4 1.7 1 1 0 1 1 1 0 FAM76 protein RNase_E_G PF10150.9 CBZ23678.1 - 4 6.8 8.9 5.3 6.4 7.2 1.9 1 1 1 2 2 2 0 Ribonuclease E/G family Spc7 PF08317.11 CBZ23678.1 - 4.4 6.1 26.0 1.8 7.4 15.6 2.6 2 1 1 3 3 3 0 Spc7 kinetochore protein PKcGMP_CC PF16808.5 CBZ23678.1 - 4.5 7.2 6.8 11 6.0 0.0 3.8 4 0 0 4 4 4 0 Coiled-coil N-terminus of cGMP-dependent protein kinase LPP PF04728.13 CBZ23678.1 - 4.8 7.7 13.7 10 6.6 0.8 4.9 4 1 0 4 4 4 0 Lipoprotein leucine-zipper CENP-F_leu_zip PF10473.9 CBZ23678.1 - 5.8 6.9 22.4 3.7 7.6 5.7 3.8 2 1 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Ax_dynein_light PF10211.9 CBZ23678.1 - 7.8 6.4 12.5 1.4 8.8 4.5 3.1 2 1 2 4 4 3 0 Axonemal dynein light chain Cation_ATPase_C PF00689.21 CBZ23679.1 - 2.2e-39 135.0 5.3 5.1e-39 133.9 5.3 1.6 1 0 0 1 1 1 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 CBZ23679.1 - 6.6e-33 113.7 0.2 4.2e-32 111.1 0.0 2.3 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_N PF00690.26 CBZ23679.1 - 1.8e-14 53.1 0.0 3.9e-14 52.1 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase PF00702.26 CBZ23679.1 - 5.5e-13 49.7 0.1 1.8e-11 44.7 0.1 3.1 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 CBZ23679.1 - 4.8e-12 45.8 0.0 1e-11 44.7 0.0 1.6 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 CBZ23679.1 - 1e-05 25.4 0.1 0.00045 20.1 0.1 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF4179 PF13786.6 CBZ23679.1 - 0.025 15.1 0.0 0.086 13.3 0.0 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4179) Sigma_reg_N PF13800.6 CBZ23679.1 - 0.051 13.9 3.2 10 6.5 0.4 3.9 4 0 0 4 4 4 0 Sigma factor regulator N-terminal DUF3935 PF13071.6 CBZ23679.1 - 0.057 14.0 1.9 0.21 12.1 0.6 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3935) YoqO PF14037.6 CBZ23679.1 - 0.61 10.6 5.2 0.28 11.7 1.9 2.1 2 0 0 2 2 2 0 YoqO-like protein DUF1980 PF09323.10 CBZ23679.1 - 0.61 10.0 2.1 0.77 9.6 0.0 2.2 3 0 0 3 3 3 0 Domain of unknown function (DUF1980) JAB PF01398.21 CBZ23680.1 - 0.0089 16.0 0.0 0.016 15.1 0.0 1.4 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Cation_ATPase_C PF00689.21 CBZ23681.1 - 5.2e-39 133.8 4.1 1.2e-38 132.7 4.1 1.6 1 0 0 1 1 1 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 CBZ23681.1 - 1.5e-32 112.6 0.2 4.3e-32 111.1 0.0 1.9 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_N PF00690.26 CBZ23681.1 - 2e-14 53.0 0.0 3.9e-14 52.1 0.0 1.5 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase PF00702.26 CBZ23681.1 - 3.7e-13 50.2 0.2 1.3e-11 45.2 0.1 3.1 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 CBZ23681.1 - 4.8e-12 45.8 0.0 1.1e-11 44.7 0.0 1.6 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 CBZ23681.1 - 5.9e-06 26.2 0.0 0.00045 20.0 0.1 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF4179 PF13786.6 CBZ23681.1 - 0.018 15.5 0.0 0.087 13.3 0.0 2.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4179) DUF1980 PF09323.10 CBZ23681.1 - 0.21 11.5 0.2 0.78 9.6 0.0 2.1 3 0 0 3 3 3 0 Domain of unknown function (DUF1980) DUF3935 PF13071.6 CBZ23681.1 - 0.31 11.6 1.7 1.1 9.8 0.5 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3935) Phage_holin_3_6 PF07332.11 CBZ23681.1 - 2.7 8.0 10.3 3.4 7.7 0.0 3.2 3 0 0 3 3 3 0 Putative Actinobacterial Holin-X, holin superfamily III V-SNARE_C PF12352.8 CBZ23683.1 - 3.8e-08 33.5 4.0 5.9e-08 32.9 4.0 1.2 1 0 0 1 1 1 1 Snare region anchored in the vesicle membrane C-terminus Prominin PF05478.11 CBZ23683.1 - 0.033 12.2 0.2 0.039 11.9 0.2 1.0 1 0 0 1 1 1 0 Prominin DUF5089 PF17002.5 CBZ23683.1 - 0.066 13.1 0.6 0.11 12.4 0.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5089) Olduvai PF06758.13 CBZ23683.1 - 0.088 13.1 0.0 0.24 11.7 0.0 1.7 1 0 0 1 1 1 0 Olduvai domain DUF4407 PF14362.6 CBZ23683.1 - 0.098 12.0 0.0 0.11 11.8 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Synaptobrevin PF00957.21 CBZ23683.1 - 0.65 9.8 2.5 2.5 7.9 2.5 1.9 1 1 0 1 1 1 0 Synaptobrevin S4 PF01479.25 CBZ23684.1 - 2.5e-13 49.5 0.3 5.7e-13 48.3 0.3 1.6 1 0 0 1 1 1 1 S4 domain Ribosomal_S4 PF00163.19 CBZ23684.1 - 1e-07 32.7 0.2 2.6e-07 31.4 0.2 1.8 1 1 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain TyrRSs_C PF16714.5 CBZ23684.1 - 0.02 14.7 0.0 0.029 14.2 0.0 1.3 1 0 0 1 1 1 0 Tyrosyl-tRNA synthetase C-terminal domain Pkinase PF00069.25 CBZ23685.1 - 1.3e-39 136.2 0.0 2.1e-25 89.6 0.0 3.6 3 1 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ23685.1 - 2e-22 79.7 0.0 4.6e-16 58.9 0.0 2.7 2 1 0 2 2 2 2 Protein tyrosine kinase Mpt_N PF09176.11 CBZ23685.1 - 0.1 12.8 0.1 0.47 10.6 0.0 2.0 2 0 0 2 2 2 0 Methylene-tetrahydromethanopterin dehydrogenase, N-terminal PAP_assoc PF03828.19 CBZ23686.1 - 0.004 17.3 0.0 0.019 15.1 0.0 2.1 1 1 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.23 CBZ23686.1 - 0.0088 16.3 0.0 0.02 15.2 0.0 1.5 1 0 0 1 1 1 1 Nucleotidyltransferase domain OmpW PF03922.14 CBZ23686.1 - 0.19 11.6 0.1 0.34 10.8 0.1 1.3 1 0 0 1 1 1 0 OmpW family EF-hand_1 PF00036.32 CBZ23687.1 - 9.7e-27 90.5 9.4 8.2e-09 34.4 0.7 4.5 5 0 0 5 5 5 4 EF hand EF-hand_7 PF13499.6 CBZ23687.1 - 1.9e-24 85.9 4.3 1.1e-12 48.2 0.9 2.9 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 CBZ23687.1 - 3e-23 79.7 3.4 1.1e-09 37.5 0.1 4.7 5 0 0 5 5 5 3 EF-hand domain EF-hand_8 PF13833.6 CBZ23687.1 - 6.6e-18 64.3 9.0 2.7e-12 46.3 0.8 3.7 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_5 PF13202.6 CBZ23687.1 - 6e-13 47.7 10.0 1.9e-05 23.9 0.1 4.2 4 0 0 4 4 4 3 EF hand EF-hand_9 PF14658.6 CBZ23687.1 - 1.6e-10 41.2 0.1 4.7e-05 23.6 0.0 2.9 3 0 0 3 3 3 2 EF-hand domain EF-hand_4 PF12763.7 CBZ23687.1 - 1.7e-06 27.9 0.6 0.0098 15.8 0.0 2.6 2 1 1 3 3 3 2 Cytoskeletal-regulatory complex EF hand SUB1_ProdP9 PF18213.1 CBZ23687.1 - 0.0012 18.6 0.1 0.0021 17.9 0.1 1.4 1 0 0 1 1 1 1 SUB1 protease Prodomain ProdP9 EF-hand_14 PF17959.1 CBZ23687.1 - 0.0048 17.2 0.3 2.4 8.6 0.1 2.7 2 2 0 2 2 2 2 EF-hand domain HEAT PF02985.22 CBZ23689.1 - 6.7e-12 44.6 16.6 0.001 19.2 0.2 10.8 11 0 0 11 11 10 3 HEAT repeat HEAT_2 PF13646.6 CBZ23689.1 - 2e-08 34.5 23.9 0.0002 21.7 0.1 8.2 7 2 3 10 10 9 2 HEAT repeats HEAT_EZ PF13513.6 CBZ23689.1 - 6.4e-06 26.6 31.7 0.047 14.2 0.3 10.5 9 1 1 10 10 10 3 HEAT-like repeat CLASP_N PF12348.8 CBZ23689.1 - 5.5e-05 22.8 0.1 0.21 11.1 0.0 3.3 3 1 0 3 3 3 2 CLASP N terminal Cnd1 PF12717.7 CBZ23689.1 - 0.00013 22.1 0.0 0.019 15.0 0.0 4.2 5 1 0 5 5 5 1 non-SMC mitotic condensation complex subunit 1 IBN_N PF03810.19 CBZ23689.1 - 0.00062 19.6 0.1 0.0079 16.1 0.0 2.8 3 0 0 3 3 3 1 Importin-beta N-terminal domain RTP1_C1 PF10363.9 CBZ23689.1 - 0.0031 17.7 0.0 1.5 9.0 0.0 3.5 3 0 0 3 3 3 1 Required for nuclear transport of RNA pol II C-terminus 1 Vac14_Fab1_bd PF12755.7 CBZ23689.1 - 0.005 17.4 0.1 1.3 9.6 0.0 4.2 4 0 0 4 4 3 1 Vacuolar 14 Fab1-binding region MMS19_C PF12460.8 CBZ23689.1 - 0.017 14.3 0.7 0.073 12.2 0.1 2.4 3 0 0 3 3 3 0 RNAPII transcription regulator C-terminal DUF3437 PF11919.8 CBZ23689.1 - 0.023 14.6 1.4 0.77 9.7 0.2 3.5 1 1 2 3 3 3 0 Domain of unknown function (DUF3437) GLE1 PF07817.13 CBZ23689.1 - 0.082 12.1 0.6 0.19 10.9 0.1 1.8 2 0 0 2 2 2 0 GLE1-like protein Adaptin_N PF01602.20 CBZ23689.1 - 0.14 10.6 0.3 5.6 5.4 0.0 3.1 3 1 0 3 3 3 0 Adaptin N terminal region Arm PF00514.23 CBZ23689.1 - 0.38 10.9 7.2 6.4 7.0 0.1 6.1 6 0 0 6 6 6 0 Armadillo/beta-catenin-like repeat MCD PF05292.11 CBZ23690.1 - 6.9e-61 206.1 0.0 2.2e-39 135.6 0.0 3.2 1 1 0 2 2 2 2 Malonyl-CoA decarboxylase C-terminal domain NIT PF08376.10 CBZ23690.1 - 0.11 13.0 0.1 0.11 13.0 0.1 2.6 3 0 0 3 3 3 0 Nitrate and nitrite sensing PPI_Ypi1 PF07491.11 CBZ23692.1 - 2.3e-17 62.6 0.9 2.3e-17 62.6 0.9 1.7 2 0 0 2 2 2 1 Protein phosphatase inhibitor DUF4399 PF14347.6 CBZ23692.1 - 0.096 13.1 0.0 0.096 13.1 0.0 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4399) IgaA PF07095.11 CBZ23693.1 - 0.22 9.4 0.0 0.29 9.1 0.0 1.1 1 0 0 1 1 1 0 Intracellular growth attenuator protein IgaA Stealth_CR3 PF17102.5 CBZ23693.1 - 2.9 7.8 6.6 3.9 7.4 0.0 3.5 5 0 0 5 5 5 0 Stealth protein CR3, conserved region 3 His_Phos_1 PF00300.22 CBZ23694.1 - 7.3e-28 97.6 0.9 1.3e-22 80.4 0.1 2.5 2 0 0 2 2 2 2 Histidine phosphatase superfamily (branch 1) 6PF2K PF01591.18 CBZ23694.1 - 3.4e-16 59.2 0.7 4.7e-09 35.9 0.0 3.4 3 0 0 3 3 3 3 6-phosphofructo-2-kinase DnaJ PF00226.31 CBZ23695.1 - 3.3e-05 23.9 0.0 0.00014 21.9 0.0 1.9 2 0 0 2 2 2 1 DnaJ domain NPR2 PF06218.11 CBZ23695.1 - 0.083 11.6 0.0 0.12 11.1 0.0 1.1 1 0 0 1 1 1 0 Nitrogen permease regulator 2 Dehydrin PF00257.19 CBZ23695.1 - 7.1 7.2 11.1 18 5.9 11.1 1.7 1 0 0 1 1 1 0 Dehydrin FAD_binding_2 PF00890.24 CBZ23698.1 - 2.2e-74 251.0 8.3 2.9e-74 250.6 8.3 1.2 1 0 0 1 1 1 1 FAD binding domain Cyt-b5 PF00173.28 CBZ23698.1 - 6.3e-20 71.1 0.1 3.9e-19 68.6 0.0 2.4 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain FAD_oxidored PF12831.7 CBZ23698.1 - 1.5e-10 41.0 3.0 7.7e-10 38.7 2.2 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase DAO PF01266.24 CBZ23698.1 - 5.9e-10 39.3 3.7 2e-07 31.0 0.2 2.6 2 1 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 CBZ23698.1 - 4.6e-08 32.6 0.1 2.6e-07 30.2 0.0 2.2 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 CBZ23698.1 - 5.5e-07 28.6 3.1 0.00051 18.9 0.2 3.0 3 0 0 3 3 3 2 HI0933-like protein NAD_binding_8 PF13450.6 CBZ23698.1 - 7.8e-07 29.2 1.9 2.8e-06 27.4 1.9 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.22 CBZ23698.1 - 4.1e-05 22.8 1.3 0.0025 16.9 0.7 2.8 3 0 0 3 3 3 1 Glucose inhibited division protein A AlaDh_PNT_C PF01262.21 CBZ23698.1 - 0.024 13.9 0.8 0.048 12.9 0.8 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Thi4 PF01946.17 CBZ23698.1 - 0.082 12.1 2.4 1.7 7.8 0.0 2.6 3 0 0 3 3 3 0 Thi4 family GMC_oxred_N PF00732.19 CBZ23698.1 - 0.11 11.8 0.4 0.28 10.5 0.0 1.7 2 0 0 2 2 2 0 GMC oxidoreductase RRM_1 PF00076.22 CBZ23699.1 - 0.0044 16.8 0.0 0.0074 16.1 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PGM_PMM_I PF02878.16 CBZ23700.1 - 2.1e-12 47.0 0.0 8.6e-09 35.2 0.0 2.5 2 0 0 2 2 2 2 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_IV PF00408.20 CBZ23700.1 - 1.2e-07 31.8 0.1 3e-07 30.5 0.1 1.8 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain PGM_PMM_III PF02880.16 CBZ23700.1 - 0.0036 17.5 0.1 0.0069 16.6 0.1 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.16 CBZ23700.1 - 0.026 15.1 0.5 0.52 11.0 0.3 2.8 2 1 0 2 2 2 0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II DUF4841 PF16129.5 CBZ23702.1 - 1 9.6 3.1 18 5.7 0.1 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4841) UQ_con PF00179.26 CBZ23705.1 - 5.7e-39 133.0 0.0 8.9e-39 132.3 0.0 1.4 1 1 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 CBZ23705.1 - 0.06 13.0 0.0 0.08 12.6 0.0 1.2 1 0 0 1 1 1 0 Prokaryotic E2 family B Pkinase PF00069.25 CBZ23708.1 - 1.1e-51 175.7 0.0 1.8e-51 175.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ23708.1 - 7.8e-35 120.4 0.1 1.6e-33 116.1 0.1 2.8 2 1 0 2 2 2 1 Protein tyrosine kinase PX PF00787.24 CBZ23708.1 - 0.014 15.4 0.2 0.031 14.3 0.0 1.6 2 0 0 2 2 2 0 PX domain Pkinase_fungal PF17667.1 CBZ23708.1 - 0.1 11.4 0.0 0.19 10.5 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase Kinase-like PF14531.6 CBZ23708.1 - 0.11 11.8 0.0 0.33 10.2 0.0 1.7 2 0 0 2 2 2 0 Kinase-like Pkinase PF00069.25 CBZ23710.1 - 1.8e-76 257.0 0.0 2.1e-76 256.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ23710.1 - 4e-39 134.5 0.0 4.8e-39 134.2 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CBZ23710.1 - 5.3e-10 39.1 0.0 1.2e-07 31.3 0.0 2.1 1 1 1 2 2 2 2 Kinase-like Haspin_kinase PF12330.8 CBZ23710.1 - 0.0019 17.2 0.1 0.0026 16.8 0.1 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 CBZ23710.1 - 0.0022 17.4 0.4 0.0045 16.4 0.3 1.4 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 CBZ23710.1 - 0.005 16.8 0.2 0.19 11.6 0.1 2.2 1 1 0 2 2 2 1 Phosphotransferase enzyme family PKD_channel PF08016.12 CBZ23711.1 - 0.00099 17.9 14.0 0.0015 17.3 14.0 1.1 1 0 0 1 1 1 1 Polycystin cation channel IML1 PF12257.8 CBZ23712.1 - 1.5e-37 129.2 0.0 1.1e-28 100.2 0.0 3.0 2 1 0 2 2 2 2 Vacuolar membrane-associated protein Iml1 Radial_spoke PF04712.12 CBZ23713.1 - 4.5e-06 25.9 9.6 0.00021 20.4 7.2 2.8 1 1 1 2 2 2 1 Radial spokehead-like protein CENP-B_dimeris PF09026.10 CBZ23713.1 - 0.0037 17.6 4.6 0.0063 16.9 4.6 1.4 1 0 0 1 1 1 1 Centromere protein B dimerisation domain BNR PF02012.20 CBZ23713.1 - 0.12 12.5 0.8 0.27 11.4 0.8 1.7 1 0 0 1 1 1 0 BNR/Asp-box repeat FAM176 PF14851.6 CBZ23713.1 - 0.48 10.1 3.0 0.8 9.4 3.0 1.3 1 0 0 1 1 1 0 FAM176 family Nucleo_P87 PF07267.11 CBZ23713.1 - 0.5 9.2 1.3 0.65 8.8 1.3 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Ribosomal_60s PF00428.19 CBZ23713.1 - 2.5 8.7 15.8 4.2 8.0 15.8 1.3 1 0 0 1 1 1 0 60s Acidic ribosomal protein DNA_pol_phi PF04931.13 CBZ23713.1 - 4.1 5.4 9.2 5 5.1 9.2 1.0 1 0 0 1 1 1 0 DNA polymerase phi CDC45 PF02724.14 CBZ23713.1 - 5.6 5.1 5.6 7.4 4.7 5.6 1.1 1 0 0 1 1 1 0 CDC45-like protein NOA36 PF06524.12 CBZ23713.1 - 8.3 5.6 9.1 13 5.0 9.1 1.2 1 0 0 1 1 1 0 NOA36 protein DUF3437 PF11919.8 CBZ23714.1 - 5.6e-18 64.6 0.0 1.9e-17 63.0 0.0 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3437) ImpE PF07024.13 CBZ23715.1 - 0.16 12.1 0.1 0.38 10.9 0.1 1.6 1 0 0 1 1 1 0 ImpE protein DUF4349 PF14257.6 CBZ23716.1 - 0.015 14.7 0.1 0.015 14.7 0.1 7.4 4 1 3 8 8 8 0 Domain of unknown function (DUF4349) NPL PF17800.1 CBZ23718.1 - 1.7e-15 57.4 0.1 2.3e-15 57.0 0.1 1.2 1 0 0 1 1 1 1 Nucleoplasmin-like domain NPL PF17800.1 CBZ23719.1 - 5e-18 65.6 0.1 5e-18 65.6 0.1 2.6 2 1 0 2 2 2 1 Nucleoplasmin-like domain NPL PF17800.1 CBZ23720.1 - 1.1e-11 45.2 0.0 1.1e-11 45.2 0.0 2.6 2 1 0 2 2 2 1 Nucleoplasmin-like domain BUD22 PF09073.10 CBZ23720.1 - 3.4 6.9 44.0 4.9 6.4 44.0 1.3 1 0 0 1 1 1 0 BUD22 FeS_assembly_P PF01883.19 CBZ23721.1 - 3.6e-10 39.9 0.0 9.6e-10 38.5 0.0 1.7 1 1 0 1 1 1 1 Iron-sulfur cluster assembly protein Glyco_hydro_1 PF00232.18 CBZ23721.1 - 0.043 12.2 0.0 0.043 12.2 0.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 1 PIF1 PF05970.14 CBZ23722.1 - 1.6e-43 149.3 0.0 9.8e-35 120.4 0.0 3.1 3 0 0 3 3 3 2 PIF1-like helicase AAA_30 PF13604.6 CBZ23722.1 - 5.7e-16 58.8 0.0 1.3e-15 57.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain Herpes_Helicase PF02689.14 CBZ23722.1 - 1.1e-10 40.1 2.7 3.6e-06 25.2 0.1 2.1 2 0 0 2 2 2 2 Helicase AAA_19 PF13245.6 CBZ23722.1 - 1.4e-09 38.5 0.0 5.9e-09 36.4 0.0 2.2 1 0 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 CBZ23722.1 - 3.7e-05 23.6 0.1 0.00092 19.0 0.0 3.1 2 1 0 2 2 2 1 Viral (Superfamily 1) RNA helicase AAA_22 PF13401.6 CBZ23722.1 - 4.9e-05 23.6 0.0 0.00012 22.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.14 CBZ23722.1 - 0.00024 21.1 0.0 0.00068 19.7 0.0 1.7 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) T2SSE PF00437.20 CBZ23722.1 - 0.0003 19.9 0.0 0.00065 18.8 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_16 PF13191.6 CBZ23722.1 - 0.00091 19.7 0.1 0.0027 18.1 0.1 1.8 1 0 0 1 1 1 1 AAA ATPase domain AAA_7 PF12775.7 CBZ23722.1 - 0.0039 16.7 0.0 0.007 15.9 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_11 PF13086.6 CBZ23722.1 - 0.0069 16.2 1.1 0.2 11.4 0.0 3.0 4 0 0 4 4 2 1 AAA domain NACHT PF05729.12 CBZ23722.1 - 0.014 15.3 0.1 0.031 14.2 0.1 1.6 1 0 0 1 1 1 0 NACHT domain AAA_24 PF13479.6 CBZ23722.1 - 0.018 14.7 0.0 0.041 13.6 0.0 1.5 1 1 0 1 1 1 0 AAA domain SH3_13 PF18335.1 CBZ23722.1 - 0.02 14.7 0.0 0.044 13.6 0.0 1.4 1 0 0 1 1 1 0 ATP-dependent RecD-like DNA helicase SH3 domain UvrD_C_2 PF13538.6 CBZ23722.1 - 0.05 13.4 0.0 0.19 11.6 0.0 2.1 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain SR-25 PF10500.9 CBZ23722.1 - 0.062 12.9 5.3 0.065 12.8 1.4 2.4 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein AFG1_ATPase PF03969.16 CBZ23722.1 - 0.062 12.2 0.0 0.12 11.3 0.0 1.4 1 0 0 1 1 1 0 AFG1-like ATPase NTPase_1 PF03266.15 CBZ23722.1 - 0.075 12.9 0.2 1.4 8.8 0.3 2.3 2 0 0 2 2 2 0 NTPase ABC_tran PF00005.27 CBZ23722.1 - 0.092 13.3 0.0 0.21 12.1 0.0 1.5 1 0 0 1 1 1 0 ABC transporter DUF2075 PF09848.9 CBZ23722.1 - 0.098 11.9 0.2 0.19 10.9 0.2 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Sigma54_activat PF00158.26 CBZ23722.1 - 0.17 11.6 0.1 0.48 10.1 0.0 1.7 2 0 0 2 2 2 0 Sigma-54 interaction domain PhoH PF02562.16 CBZ23722.1 - 0.18 11.3 0.0 0.32 10.4 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein Rotamase PF00639.21 CBZ23723.1 - 4.9e-22 78.7 0.0 5.6e-22 78.5 0.0 1.0 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_3 PF13616.6 CBZ23723.1 - 3.2e-17 63.2 0.0 3.7e-17 62.9 0.0 1.1 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_2 PF13145.6 CBZ23723.1 - 0.003 18.4 0.0 0.0037 18.1 0.0 1.2 1 0 0 1 1 1 1 PPIC-type PPIASE domain Exonuc_VII_S PF02609.16 CBZ23723.1 - 0.0098 15.9 0.2 0.098 12.7 0.1 2.0 2 0 0 2 2 2 1 Exonuclease VII small subunit Sel1 PF08238.12 CBZ23725.1 - 2.9e-06 27.8 6.1 0.077 13.7 0.0 3.6 3 2 0 3 3 3 2 Sel1 repeat E1-E2_ATPase PF00122.20 CBZ23726.1 - 7.2e-22 77.8 0.0 7.2e-22 77.8 0.0 2.1 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.26 CBZ23726.1 - 1.4e-12 48.4 0.7 1.5e-05 25.4 0.3 2.9 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 CBZ23726.1 - 0.0015 18.6 0.0 0.0038 17.3 0.0 1.7 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 CBZ23726.1 - 0.013 15.3 0.3 0.049 13.4 0.1 2.0 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase Dpy-30 PF05186.13 CBZ23727.1 - 9.9e-12 44.4 0.0 1.4e-11 43.8 0.0 1.3 1 0 0 1 1 1 1 Dpy-30 motif BPL_LplA_LipB PF03099.19 CBZ23728.1 - 5e-09 36.2 0.0 1.6e-08 34.5 0.0 1.8 1 1 0 1 1 1 1 Biotin/lipoate A/B protein ligase family zf-C2H2 PF00096.26 CBZ23729.1 - 3.3e-07 30.4 7.5 0.00097 19.5 0.7 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CBZ23729.1 - 4.5e-06 27.0 9.7 0.015 16.0 0.4 3.2 3 0 0 3 3 2 2 C2H2-type zinc finger zf-C2H2_3rep PF18868.1 CBZ23729.1 - 0.00016 22.3 0.6 0.64 10.7 0.1 2.4 2 0 0 2 2 2 2 Zinc finger C2H2-type, 3 repeats zf-C2H2_2 PF12756.7 CBZ23729.1 - 0.0011 19.3 1.1 0.19 12.1 0.1 2.4 2 0 0 2 2 2 1 C2H2 type zinc-finger (2 copies) DUF629 PF04780.12 CBZ23729.1 - 0.003 16.2 1.0 1.1 7.7 0.1 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF629) zf-Di19 PF05605.12 CBZ23729.1 - 0.012 15.9 1.5 2.2 8.6 0.5 2.5 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding TFIIS_C PF01096.18 CBZ23729.1 - 0.043 13.7 3.4 0.32 10.9 0.5 2.7 2 0 0 2 2 2 0 Transcription factor S-II (TFIIS) zf-met PF12874.7 CBZ23729.1 - 0.076 13.4 3.2 0.12 12.8 1.1 2.2 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-trcl PF13451.6 CBZ23729.1 - 0.09 12.7 1.0 1.3 9.0 0.1 2.4 2 0 0 2 2 2 0 Probable zinc-ribbon domain PHD_Oberon PF07227.11 CBZ23729.1 - 0.098 12.5 1.5 1.2 9.0 0.3 2.3 2 0 0 2 2 2 0 PHD - plant homeodomain finger protein zf_C2H2_ZHX PF18387.1 CBZ23729.1 - 0.12 12.0 1.6 8.2 6.2 0.3 2.4 2 0 0 2 2 2 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-C2H2_6 PF13912.6 CBZ23729.1 - 0.26 11.3 6.2 1.5 8.9 0.7 2.4 2 0 0 2 2 2 0 C2H2-type zinc finger zf-met2 PF12907.7 CBZ23729.1 - 0.37 11.0 6.0 0.073 13.2 1.3 2.2 2 0 0 2 2 2 0 Zinc-binding zf-LYAR PF08790.11 CBZ23729.1 - 1.7 8.6 3.5 18 5.3 0.4 2.9 3 0 0 3 3 3 0 LYAR-type C2HC zinc finger PQQ_2 PF13360.6 CBZ23730.1 - 0.0024 17.5 6.7 0.18 11.4 0.3 3.7 3 1 0 3 3 3 2 PQQ-like domain DUF1601 PF07671.11 CBZ23730.1 - 0.037 13.9 0.1 0.11 12.4 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1601) CHAP PF05257.16 CBZ23730.1 - 0.21 12.2 2.1 2.3 8.9 2.1 2.5 1 1 0 1 1 1 0 CHAP domain Spc7 PF08317.11 CBZ23730.1 - 2.4 7.0 26.8 0.021 13.7 12.9 2.3 1 1 1 2 2 2 0 Spc7 kinetochore protein YjbH PF06082.11 CBZ23730.1 - 5.3 5.7 8.3 7.2 5.3 8.3 1.1 1 0 0 1 1 1 0 Exopolysaccharide biosynthesis protein YbjH FA_desaturase PF00487.24 CBZ23731.1 - 9e-40 137.1 20.2 1.4e-39 136.5 20.2 1.2 1 0 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.28 CBZ23731.1 - 0.00055 20.0 0.0 0.0012 18.9 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain VWA_2 PF13519.6 CBZ23735.1 - 6.1e-13 49.3 0.1 7.3e-12 45.9 0.0 2.4 1 1 1 2 2 2 1 von Willebrand factor type A domain UIM PF02809.20 CBZ23735.1 - 9.8e-07 28.3 11.1 0.00047 19.9 3.8 3.3 2 0 0 2 2 2 2 Ubiquitin interaction motif VWA PF00092.28 CBZ23735.1 - 0.0024 18.1 0.3 0.0039 17.5 0.3 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain Methyltransf_33 PF10017.9 CBZ23735.1 - 0.11 11.6 0.0 0.2 10.8 0.0 1.3 1 1 0 1 1 1 0 Histidine-specific methyltransferase, SAM-dependent Nif11 PF07862.11 CBZ23736.1 - 0.068 13.5 0.1 39 4.7 0.0 3.6 4 0 0 4 4 4 0 Nif11 domain PMSR PF01625.21 CBZ23737.1 - 2.7e-53 180.2 0.7 3.4e-53 179.9 0.7 1.1 1 0 0 1 1 1 1 Peptide methionine sulfoxide reductase Chorein_N PF12624.7 CBZ23738.1 - 2.1e-07 31.0 0.0 5.6e-07 29.7 0.0 1.7 1 0 0 1 1 1 1 N-terminal region of Chorein or VPS13 VPS13_C PF16909.5 CBZ23738.1 - 0.0062 16.3 0.0 0.012 15.4 0.0 1.4 1 0 0 1 1 1 1 Vacuolar-sorting-associated 13 protein C-terminal Aa_trans PF01490.18 CBZ23739.1 - 2.8e-57 194.3 21.8 3.2e-57 194.1 21.8 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 CBZ23739.1 - 5.7e-11 42.1 10.4 5.7e-11 42.1 10.4 1.9 2 0 0 2 2 2 1 Tryptophan/tyrosine permease family Galactosyl_T PF01762.21 CBZ23740.1 - 0.0004 20.3 0.2 0.0013 18.5 0.0 1.9 2 0 0 2 2 2 1 Galactosyltransferase Ribosomal_S19e PF01090.19 CBZ23742.1 - 9.8e-43 145.1 0.0 1.2e-42 144.9 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S19e Mrr_N PF14338.6 CBZ23742.1 - 0.01 15.9 0.0 0.017 15.2 0.0 1.4 1 0 0 1 1 1 0 Mrr N-terminal domain RRM_1 PF00076.22 CBZ23745.1 - 9.5e-18 63.8 0.0 1.4e-17 63.3 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Metaviral_G PF09595.10 CBZ23745.1 - 0.056 13.5 3.3 0.16 12.1 2.4 2.0 2 0 0 2 2 2 0 Metaviral_G glycoprotein LRR_6 PF13516.6 CBZ23747.1 - 4.7e-37 122.9 33.6 0.00055 19.8 0.1 13.4 13 0 0 13 13 13 12 Leucine Rich repeat LRR_1 PF00560.33 CBZ23747.1 - 5.5e-12 44.5 7.2 8.4 7.4 0.1 10.5 11 0 0 11 11 11 2 Leucine Rich Repeat LRR_4 PF12799.7 CBZ23747.1 - 7.1e-10 39.0 10.9 0.32 11.5 0.1 6.6 6 0 0 6 6 6 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CBZ23747.1 - 0.00052 19.7 25.4 2.5 7.9 1.0 7.9 5 5 0 5 5 5 4 Leucine rich repeat DUF489 PF04356.12 CBZ23747.1 - 0.11 12.5 0.7 0.27 11.2 0.7 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF489) DUF4407 PF14362.6 CBZ23747.1 - 0.41 9.9 10.7 0.85 8.9 10.7 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Occludin_ELL PF07303.13 CBZ23747.1 - 0.64 10.8 6.9 0.4 11.4 3.9 2.1 1 1 1 2 2 2 0 Occludin homology domain DUF1664 PF07889.12 CBZ23747.1 - 5.4 7.1 8.3 6.8 6.7 0.9 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) IU_nuc_hydro PF01156.19 CBZ23748.1 - 4.7e-44 151.2 0.1 6e-44 150.8 0.1 1.1 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase DUF1759 PF03564.15 CBZ23748.1 - 0.09 12.7 0.1 0.26 11.2 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1759) Mito_carr PF00153.27 CBZ23750.1 - 2.1e-58 194.3 0.5 5.1e-20 71.2 0.0 3.1 2 1 1 3 3 3 3 Mitochondrial carrier protein ThrE_2 PF12821.7 CBZ23750.1 - 0.0011 19.1 0.3 0.21 11.8 0.1 2.5 2 0 0 2 2 2 2 Threonine/Serine exporter, ThrE Trypsin_2 PF13365.6 CBZ23751.1 - 0.0081 17.1 3.5 0.035 15.0 3.5 1.8 1 1 0 1 1 1 1 Trypsin-like peptidase domain TPR_19 PF14559.6 CBZ23752.1 - 3.4e-10 40.3 3.7 0.0067 16.9 0.1 5.3 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_16 PF13432.6 CBZ23752.1 - 3.5e-09 37.2 2.2 0.088 13.5 0.1 4.3 3 1 1 4 4 4 4 Tetratricopeptide repeat TPR_2 PF07719.17 CBZ23752.1 - 7.1e-08 32.0 21.9 0.053 13.7 0.0 6.8 7 0 0 7 7 7 4 Tetratricopeptide repeat ANAPC3 PF12895.7 CBZ23752.1 - 0.00041 20.5 19.5 0.37 11.0 1.8 5.1 3 1 3 6 6 6 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_1 PF00515.28 CBZ23752.1 - 0.00075 19.2 17.2 0.15 11.9 0.3 5.0 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_14 PF13428.6 CBZ23752.1 - 0.0022 18.7 6.9 25 6.1 0.2 5.4 6 0 0 6 6 5 0 Tetratricopeptide repeat TPR_11 PF13414.6 CBZ23752.1 - 0.0026 17.4 1.3 0.76 9.5 0.1 2.9 2 0 0 2 2 2 2 TPR repeat TPR_12 PF13424.6 CBZ23752.1 - 0.0041 17.4 9.7 1.2 9.4 0.3 5.1 4 2 0 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.6 CBZ23752.1 - 0.027 14.5 3.3 0.45 10.7 0.1 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.6 CBZ23752.1 - 0.21 11.9 14.4 2.4 8.6 0.2 6.0 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_6 PF13174.6 CBZ23752.1 - 2.5 8.9 12.0 7 7.5 0.1 5.5 6 0 0 6 6 6 0 Tetratricopeptide repeat Actin PF00022.19 CBZ23754.1 - 4e-18 65.2 0.0 4.5e-12 45.3 0.0 2.3 2 1 0 2 2 2 2 Actin ODC_AZ PF02100.17 CBZ23754.1 - 0.11 12.5 0.0 0.19 11.7 0.0 1.5 1 1 0 1 1 1 0 Ornithine decarboxylase antizyme START PF01852.19 CBZ23755.1 - 9.3e-28 97.1 0.0 1.5e-27 96.4 0.0 1.2 1 0 0 1 1 1 1 START domain DUF3074 PF11274.8 CBZ23755.1 - 0.18 11.8 0.0 1.6 8.7 0.0 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF3074) Pkinase PF00069.25 CBZ23756.1 - 4.6e-37 127.8 0.0 2.4e-35 122.2 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ23756.1 - 1.1e-16 60.9 0.0 1.6e-16 60.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 CBZ23756.1 - 8.7e-05 22.0 0.0 0.00016 21.1 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family TolA_bind_tri PF16331.5 CBZ23756.1 - 0.16 12.0 2.2 0.71 10.0 0.1 2.8 3 0 0 3 3 3 0 TolA binding protein trimerisation Beta_helix PF13229.6 CBZ23757.1 - 7.7e-23 81.1 2.7 2.4e-17 63.2 0.4 2.1 1 1 1 2 2 2 2 Right handed beta helix region NosD PF05048.13 CBZ23757.1 - 5e-10 39.1 0.0 8.1e-10 38.4 0.0 1.4 1 1 0 1 1 1 1 Periplasmic copper-binding protein (NosD) Pectate_lyase_3 PF12708.7 CBZ23757.1 - 0.0049 16.7 0.1 0.11 12.4 0.0 2.3 2 0 0 2 2 2 1 Pectate lyase superfamily protein Phage_Coat_A PF05357.13 CBZ23759.1 - 5.1 7.0 11.8 2.1 8.2 0.1 3.0 3 0 0 3 3 3 0 Phage Coat Protein A PDEase_I PF00233.19 CBZ23760.1 - 6.5e-46 157.0 0.0 6.5e-46 157.0 0.0 3.0 3 1 1 4 4 4 1 3'5'-cyclic nucleotide phosphodiesterase FYVE PF01363.21 CBZ23760.1 - 5.1e-08 32.9 12.6 1.3e-07 31.6 12.6 1.7 1 0 0 1 1 1 1 FYVE zinc finger TMF_DNA_bd PF12329.8 CBZ23760.1 - 0.0086 16.1 3.0 0.0086 16.1 3.0 7.6 6 2 0 7 7 7 1 TATA element modulatory factor 1 DNA binding Uso1_p115_C PF04871.13 CBZ23760.1 - 0.034 14.5 0.6 0.034 14.5 0.6 7.1 2 2 3 5 5 5 0 Uso1 / p115 like vesicle tethering protein, C terminal region Spc7 PF08317.11 CBZ23760.1 - 0.87 8.4 78.2 0.18 10.7 10.3 4.7 2 1 2 4 4 4 0 Spc7 kinetochore protein PKcGMP_CC PF16808.5 CBZ23760.1 - 5.7 6.9 8.7 9.8 6.1 0.2 4.4 5 0 0 5 5 5 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Pkinase PF00069.25 CBZ23761.1 - 4.4e-64 216.4 0.0 6.1e-64 215.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ23761.1 - 1.8e-40 138.9 0.0 2.5e-40 138.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CBZ23761.1 - 0.00017 20.5 0.0 0.00039 19.3 0.0 1.6 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 CBZ23761.1 - 0.00035 20.0 0.1 0.00093 18.6 0.0 1.7 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 CBZ23761.1 - 0.0013 18.8 0.2 0.49 10.3 0.0 2.6 2 1 1 3 3 3 2 Phosphotransferase enzyme family FTA2 PF13095.6 CBZ23761.1 - 0.03 13.9 0.0 0.46 10.1 0.0 2.1 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Haspin_kinase PF12330.8 CBZ23761.1 - 0.078 11.9 0.1 10 5.0 0.0 2.1 2 0 0 2 2 2 0 Haspin like kinase domain Helicase_C_2 PF13307.6 CBZ23762.1 - 1.2e-49 168.7 0.0 3.1e-49 167.4 0.0 1.7 1 0 0 1 1 1 1 Helicase C-terminal domain DEAD_2 PF06733.15 CBZ23762.1 - 1.2e-43 148.7 0.2 4.5e-43 146.9 0.0 1.9 2 0 0 2 2 2 1 DEAD_2 DEAD PF00270.29 CBZ23762.1 - 0.00027 20.7 0.0 0.008 16.0 0.0 2.3 2 0 0 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.15 CBZ23762.1 - 0.00029 20.9 0.0 0.027 14.5 0.0 2.3 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit HBB PF06777.11 CBZ23762.1 - 0.00079 19.2 0.0 0.002 17.8 0.0 1.6 1 0 0 1 1 1 1 Helical and beta-bridge domain AAA_11 PF13086.6 CBZ23762.1 - 0.0066 16.3 0.2 0.22 11.3 0.0 2.5 2 0 0 2 2 2 1 AAA domain DUF2017 PF09438.10 CBZ23762.1 - 0.012 15.5 0.9 0.031 14.1 0.2 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF2017) PhoH PF02562.16 CBZ23762.1 - 0.013 15.0 0.0 28 4.1 0.0 3.9 4 0 0 4 4 4 0 PhoH-like protein Cnd3 PF12719.7 CBZ23763.1 - 1.8e-34 119.3 0.4 1.8e-34 119.3 0.4 2.3 2 0 0 2 2 2 1 Nuclear condensing complex subunits, C-term domain Cnd1 PF12717.7 CBZ23763.1 - 7.7e-07 29.3 0.6 0.044 13.8 0.3 4.4 4 1 1 5 5 5 2 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 CBZ23763.1 - 1.5e-06 27.9 8.9 1.8 9.0 0.0 6.8 6 0 0 6 6 6 3 HEAT repeat HEAT_2 PF13646.6 CBZ23763.1 - 4e-06 27.1 3.2 0.0007 19.9 0.2 5.3 4 3 4 8 8 8 3 HEAT repeats SspB PF04386.13 CBZ23763.1 - 0.028 14.3 0.0 12 5.8 0.0 2.7 2 0 0 2 2 2 0 Stringent starvation protein B DUF802 PF05650.11 CBZ23763.1 - 0.31 11.6 5.5 0.17 12.4 2.3 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF802) ACOX PF01756.19 CBZ23763.1 - 1.4 8.5 4.2 0.68 9.5 0.7 2.2 2 0 0 2 2 2 0 Acyl-CoA oxidase DUF3458_C PF17432.2 CBZ23763.1 - 3.7 6.8 11.3 1.5 8.1 3.2 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3458_C) ARM repeats Arm PF00514.23 CBZ23764.1 - 0.01 15.8 6.5 1.4 9.1 0.4 4.3 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat SAM_1 PF00536.30 CBZ23765.1 - 9.8e-05 22.7 0.0 0.00031 21.1 0.0 1.9 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 CBZ23765.1 - 0.013 15.6 0.0 0.03 14.4 0.0 1.7 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) DUF1804 PF08822.11 CBZ23765.1 - 0.08 12.9 3.2 0.39 10.7 0.1 3.1 3 1 0 3 3 3 0 Protein of unknown function (DUF1804) DnaB_bind PF10410.9 CBZ23765.1 - 0.099 12.8 2.9 0.48 10.6 0.0 3.5 3 1 1 4 4 4 0 DnaB-helicase binding domain of primase CBF PF03914.17 CBZ23765.1 - 0.58 10.2 3.1 1.5 8.8 0.1 3.0 3 1 0 3 3 3 0 CBF/Mak21 family DinB_2 PF12867.7 CBZ23765.1 - 5.4 7.5 9.5 5.9 7.4 0.2 4.8 3 2 1 4 4 4 0 DinB superfamily GAS PF13851.6 CBZ23767.1 - 5.7 6.2 18.7 0.012 15.0 6.7 2.7 4 1 0 4 4 4 0 Growth-arrest specific micro-tubule binding PAP_central PF04928.17 CBZ23768.1 - 7.7e-37 126.6 0.0 1e-36 126.2 0.0 1.1 1 0 0 1 1 1 1 Poly(A) polymerase central domain PAP_RNA-bind PF04926.15 CBZ23768.1 - 2.3e-05 24.1 0.0 4.1e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 Poly(A) polymerase predicted RNA binding domain NTP_transf_2 PF01909.23 CBZ23768.1 - 5.6e-05 23.4 0.0 9.7e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 Nucleotidyltransferase domain Polbeta PF18765.1 CBZ23768.1 - 0.0052 16.8 0.0 0.01 15.9 0.0 1.4 1 0 0 1 1 1 1 Polymerase beta, Nucleotidyltransferase NACHT_N PF17100.5 CBZ23768.1 - 0.13 12.1 0.2 0.2 11.5 0.2 1.2 1 0 0 1 1 1 0 N-terminal domain of NWD NACHT-NTPase DCX PF03607.17 CBZ23769.1 - 8.6e-06 25.8 0.1 0.00017 21.6 0.0 2.4 2 0 0 2 2 2 1 Doublecortin Pkinase PF00069.25 CBZ23771.1 - 5.6e-65 219.3 0.0 8.5e-65 218.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ23771.1 - 2.4e-44 151.5 0.0 4.5e-44 150.7 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CBZ23771.1 - 2.4e-05 23.8 0.0 4.1e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 CBZ23771.1 - 0.02 14.8 0.5 6.4 6.6 0.0 2.7 2 1 1 3 3 3 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 CBZ23771.1 - 0.042 12.6 0.4 0.094 11.5 0.0 1.7 2 0 0 2 2 2 0 Fungal protein kinase APC_u15 PF16636.5 CBZ23771.1 - 0.19 12.2 5.8 0.31 11.5 4.7 2.0 1 1 1 2 2 2 0 Unstructured region on APC between APC_crr regions 5 and 6 DUF4586 PF15239.6 CBZ23772.1 - 8.1e-63 213.4 12.4 1e-62 213.1 12.4 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4586) TPR_19 PF14559.6 CBZ23773.1 - 6.4e-21 74.6 23.9 7.8e-06 26.3 0.8 8.7 7 3 1 8 8 8 6 Tetratricopeptide repeat TPR_14 PF13428.6 CBZ23773.1 - 2.6e-17 62.0 32.4 0.00077 20.1 0.1 10.5 8 2 3 11 11 11 5 Tetratricopeptide repeat TPR_16 PF13432.6 CBZ23773.1 - 3.9e-13 49.8 28.9 0.00032 21.3 0.8 9.6 10 0 0 10 10 9 4 Tetratricopeptide repeat ANAPC3 PF12895.7 CBZ23773.1 - 1.2e-07 31.8 11.9 0.26 11.5 0.1 5.8 6 0 0 6 6 6 3 Anaphase-promoting complex, cyclosome, subunit 3 HrpB1_HrpK PF09613.10 CBZ23773.1 - 2.5e-07 30.4 18.0 0.0049 16.5 0.8 5.1 6 1 0 6 6 6 2 Bacterial type III secretion protein (HrpB1_HrpK) TPR_17 PF13431.6 CBZ23773.1 - 1.1e-06 28.5 9.8 7 7.3 0.2 7.8 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_2 PF07719.17 CBZ23773.1 - 1.1e-05 25.1 25.2 0.15 12.2 0.0 10.1 12 0 0 12 12 11 1 Tetratricopeptide repeat TPR_1 PF00515.28 CBZ23773.1 - 0.00013 21.6 2.9 0.65 9.9 0.0 6.6 8 0 0 8 8 7 1 Tetratricopeptide repeat TPR_12 PF13424.6 CBZ23773.1 - 0.00047 20.4 33.2 0.58 10.5 0.0 9.8 8 3 1 10 10 10 2 Tetratricopeptide repeat TPR_11 PF13414.6 CBZ23773.1 - 0.0012 18.5 4.3 2 8.2 0.0 5.7 7 0 0 7 7 7 1 TPR repeat TPR_20 PF14561.6 CBZ23773.1 - 0.0013 19.0 5.0 0.014 15.7 0.3 4.5 5 0 0 5 5 4 1 Tetratricopeptide repeat Topoisom_bac PF01131.20 CBZ23773.1 - 0.0028 16.7 0.2 0.0055 15.8 0.2 1.4 1 0 0 1 1 1 1 DNA topoisomerase NatB_MDM20 PF09797.9 CBZ23773.1 - 0.0054 15.7 2.6 0.028 13.3 0.2 2.6 3 0 0 3 3 3 1 N-acetyltransferase B complex (NatB) non catalytic subunit TPR_4 PF07721.14 CBZ23773.1 - 0.024 15.3 41.1 3 8.7 0.2 10.0 9 0 0 9 9 9 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 CBZ23773.1 - 0.048 13.7 2.0 17 5.6 0.0 4.8 5 0 0 5 5 5 0 Fis1 C-terminal tetratricopeptide repeat TPR_6 PF13174.6 CBZ23773.1 - 0.17 12.6 0.0 0.17 12.6 0.0 7.5 9 0 0 9 9 6 0 Tetratricopeptide repeat TPR_15 PF13429.6 CBZ23773.1 - 0.86 8.8 30.6 0.12 11.5 1.2 4.8 4 2 1 5 5 5 0 Tetratricopeptide repeat TPR_9 PF13371.6 CBZ23773.1 - 3.1 8.0 16.8 15 5.8 0.1 5.5 5 0 0 5 5 5 0 Tetratricopeptide repeat Methyltr_RsmB-F PF01189.17 CBZ23774.1 - 3.9e-40 137.7 0.1 1.1e-38 132.9 0.1 2.2 1 1 0 1 1 1 1 16S rRNA methyltransferase RsmB/F FtsJ PF01728.19 CBZ23774.1 - 1.7e-05 25.0 0.0 4.6e-05 23.6 0.0 1.8 1 1 0 1 1 1 1 FtsJ-like methyltransferase Methyltr_RsmF_N PF17125.5 CBZ23774.1 - 0.17 12.4 0.0 0.73 10.4 0.0 2.1 1 1 0 1 1 1 0 N-terminal domain of 16S rRNA methyltransferase RsmF zf-MIZ PF02891.20 CBZ23776.1 - 7.5e-10 38.4 0.5 5.9e-09 35.5 0.0 2.4 2 0 0 2 2 2 1 MIZ/SP-RING zinc finger zf-Nse PF11789.8 CBZ23776.1 - 0.02 14.7 0.2 0.047 13.5 0.2 1.6 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit CMV_1a PF12467.8 CBZ23776.1 - 1.3 9.3 5.1 5.5 7.3 0.7 3.2 2 1 0 3 3 3 0 Cucumber mosaic virus 1a protein family Glucodextran_B PF09136.10 CBZ23776.1 - 2.9 8.3 6.1 8.2 6.9 0.2 3.2 3 0 0 3 3 3 0 Glucodextranase, domain B PFK PF00365.20 CBZ23777.1 - 2.2e-63 214.2 0.2 2.8e-63 213.9 0.2 1.1 1 0 0 1 1 1 1 Phosphofructokinase DAGK_cat PF00781.24 CBZ23777.1 - 4.1e-05 23.2 0.3 9.8e-05 22.0 0.1 1.7 2 0 0 2 2 2 1 Diacylglycerol kinase catalytic domain NAD_kinase PF01513.21 CBZ23777.1 - 0.022 14.0 0.0 0.048 12.9 0.0 1.6 1 1 0 1 1 1 0 ATP-NAD kinase AAA PF00004.29 CBZ23778.1 - 5e-40 137.0 0.0 1.2e-39 135.7 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.10 CBZ23778.1 - 8.5e-25 86.5 0.1 2.6e-24 85.0 0.1 1.9 2 0 0 2 2 1 1 Vps4 C terminal oligomerisation domain MIT PF04212.18 CBZ23778.1 - 1.2e-16 60.5 3.0 1.2e-16 60.5 3.0 2.1 2 0 0 2 2 1 1 MIT (microtubule interacting and transport) domain AAA_lid_3 PF17862.1 CBZ23778.1 - 2.8e-09 36.7 0.1 1.2e-07 31.4 0.0 3.0 3 0 0 3 3 3 1 AAA+ lid domain AAA_2 PF07724.14 CBZ23778.1 - 6.8e-06 26.3 0.0 1.6e-05 25.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 CBZ23778.1 - 7.6e-06 26.4 0.2 0.00054 20.4 0.0 2.7 2 1 1 3 3 3 1 AAA ATPase domain AAA_22 PF13401.6 CBZ23778.1 - 3.9e-05 23.9 0.1 0.004 17.4 0.1 2.6 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.14 CBZ23778.1 - 0.00015 21.8 0.0 0.00085 19.3 0.0 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) DUF815 PF05673.13 CBZ23778.1 - 0.00047 19.4 0.0 0.0008 18.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) RuvB_N PF05496.12 CBZ23778.1 - 0.00065 19.5 0.0 0.0016 18.2 0.0 1.6 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain IstB_IS21 PF01695.17 CBZ23778.1 - 0.00065 19.5 0.0 0.0013 18.5 0.0 1.6 1 1 0 1 1 1 1 IstB-like ATP binding protein AAA_33 PF13671.6 CBZ23778.1 - 0.0015 18.7 0.0 0.0035 17.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain USP8_dimer PF08969.11 CBZ23778.1 - 0.002 18.3 3.2 0.0052 17.0 3.2 1.7 1 0 0 1 1 1 1 USP8 dimerisation domain AAA_24 PF13479.6 CBZ23778.1 - 0.002 17.9 0.0 0.0051 16.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain TIP49 PF06068.13 CBZ23778.1 - 0.0024 17.1 0.0 0.0037 16.5 0.0 1.2 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_14 PF13173.6 CBZ23778.1 - 0.0025 17.8 0.0 0.0095 16.0 0.0 1.9 2 0 0 2 2 1 1 AAA domain AAA_18 PF13238.6 CBZ23778.1 - 0.0068 16.9 0.0 0.018 15.6 0.0 1.8 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 CBZ23778.1 - 0.0096 16.3 0.0 0.021 15.2 0.0 1.6 1 0 0 1 1 1 1 RNA helicase AAA_25 PF13481.6 CBZ23778.1 - 0.0096 15.5 0.4 0.75 9.3 0.1 2.4 1 1 1 2 2 2 1 AAA domain AAA_17 PF13207.6 CBZ23778.1 - 0.015 15.7 0.0 0.078 13.4 0.0 2.2 2 0 0 2 2 2 0 AAA domain Viral_helicase1 PF01443.18 CBZ23778.1 - 0.025 14.3 0.0 0.043 13.6 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase ATPase_2 PF01637.18 CBZ23778.1 - 0.035 14.0 2.7 2.8 7.8 0.0 2.9 3 1 1 4 4 3 0 ATPase domain predominantly from Archaea Mg_chelatase PF01078.21 CBZ23778.1 - 0.049 13.0 0.0 0.099 12.0 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI CPT PF07931.12 CBZ23778.1 - 0.056 13.3 0.0 0.16 11.8 0.0 1.9 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein Parvo_NS1 PF01057.17 CBZ23778.1 - 0.058 12.5 0.0 0.12 11.5 0.0 1.4 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 NACHT PF05729.12 CBZ23778.1 - 0.089 12.7 0.0 0.69 9.8 0.0 2.2 2 0 0 2 2 2 0 NACHT domain AFG1_ATPase PF03969.16 CBZ23778.1 - 0.093 11.6 0.0 0.14 11.0 0.0 1.3 1 0 0 1 1 1 0 AFG1-like ATPase AAA_7 PF12775.7 CBZ23778.1 - 0.1 12.1 0.0 0.32 10.5 0.0 1.8 2 1 0 2 2 2 0 P-loop containing dynein motor region PPV_E1_C PF00519.17 CBZ23778.1 - 0.11 11.3 0.0 0.16 10.8 0.0 1.2 1 0 0 1 1 1 0 Papillomavirus helicase PhoH PF02562.16 CBZ23778.1 - 0.13 11.7 0.2 0.32 10.4 0.2 1.6 1 0 0 1 1 1 0 PhoH-like protein Sigma54_activat PF00158.26 CBZ23778.1 - 0.17 11.6 0.0 0.45 10.2 0.0 1.7 1 1 0 1 1 1 0 Sigma-54 interaction domain Pkinase PF00069.25 CBZ23779.1 - 3.5e-42 144.6 0.0 5.1e-42 144.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ23779.1 - 9.3e-35 120.1 0.0 1.1e-34 119.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CBZ23779.1 - 0.0033 16.3 0.0 0.007 15.2 0.0 1.6 2 0 0 2 2 2 1 Fungal protein kinase APH PF01636.23 CBZ23779.1 - 0.022 14.7 0.3 0.035 14.0 0.3 1.5 1 1 0 1 1 1 0 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.11 CBZ23779.1 - 0.082 11.9 0.1 0.13 11.2 0.1 1.3 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Haspin_kinase PF12330.8 CBZ23779.1 - 0.12 11.3 0.4 0.23 10.4 0.4 1.5 1 1 0 1 1 1 0 Haspin like kinase domain Ribosomal_L13e PF01294.18 CBZ23781.1 - 5.8e-63 212.0 4.6 8.2e-63 211.5 4.6 1.2 1 0 0 1 1 1 1 Ribosomal protein L13e PTPS PF01242.19 CBZ23781.1 - 0.034 14.1 0.0 0.05 13.6 0.0 1.2 1 0 0 1 1 1 0 6-pyruvoyl tetrahydropterin synthase Ribosomal_L13e PF01294.18 CBZ23782.1 - 5.8e-63 212.0 4.6 8.2e-63 211.5 4.6 1.2 1 0 0 1 1 1 1 Ribosomal protein L13e PTPS PF01242.19 CBZ23782.1 - 0.034 14.1 0.0 0.05 13.6 0.0 1.2 1 0 0 1 1 1 0 6-pyruvoyl tetrahydropterin synthase HSP20 PF00011.21 CBZ23783.1 - 2.5e-17 62.9 0.0 3.1e-17 62.6 0.0 1.1 1 0 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 CBZ23783.1 - 8.9e-09 34.8 0.0 2.1e-08 33.6 0.0 1.6 1 1 0 1 1 1 1 HSP20-like domain found in ArsA PapC_N PF13954.6 CBZ23783.1 - 0.0062 16.5 0.0 0.0079 16.2 0.0 1.2 1 0 0 1 1 1 1 PapC N-terminal domain PDEase_I PF00233.19 CBZ23784.1 - 1.1e-75 254.5 2.8 2.3e-75 253.4 2.8 1.6 2 0 0 2 2 2 1 3'5'-cyclic nucleotide phosphodiesterase Acyltransferase PF01553.21 CBZ23787.1 - 8e-11 41.7 0.0 1.4e-10 40.9 0.0 1.4 1 0 0 1 1 1 1 Acyltransferase JmjN PF02375.17 CBZ23787.1 - 0.029 14.3 0.0 0.058 13.4 0.0 1.5 1 0 0 1 1 1 0 jmjN domain NIF PF03031.18 CBZ23788.1 - 2.8e-29 101.9 0.0 3.9e-29 101.4 0.0 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase DUF705 PF05152.12 CBZ23788.1 - 0.0002 20.9 0.0 0.00029 20.4 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF705) Kinesin PF00225.23 CBZ23789.1 - 1.6e-92 310.0 0.0 2.4e-92 309.4 0.0 1.2 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 CBZ23789.1 - 5.7e-20 71.8 0.0 1.6e-19 70.4 0.0 1.8 1 0 0 1 1 1 1 Microtubule binding C2 PF00168.30 CBZ23789.1 - 6.7e-05 23.1 0.0 0.00021 21.5 0.0 1.9 2 0 0 2 2 2 1 C2 domain Caldesmon PF02029.15 CBZ23789.1 - 0.022 13.6 4.2 0.088 11.6 4.3 1.7 1 1 0 1 1 1 0 Caldesmon GAS PF13851.6 CBZ23789.1 - 0.042 13.2 3.1 0.1 11.9 3.1 1.6 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding DUF16 PF01519.16 CBZ23789.1 - 0.65 10.5 4.0 6.6 7.3 0.5 2.5 2 0 0 2 2 2 0 Protein of unknown function DUF16 STN1_2 PF09170.10 CBZ23789.1 - 0.92 9.7 4.9 0.34 11.1 0.8 2.1 2 0 0 2 2 2 0 CST, Suppressor of cdc thirteen homolog, complex subunit STN1 Kinesin PF00225.23 CBZ23790.1 - 2.2e-92 309.6 0.0 2.8e-92 309.2 0.0 1.1 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 CBZ23790.1 - 1.2e-19 70.7 0.0 4.5e-19 68.8 0.0 1.9 2 0 0 2 2 2 1 Microtubule binding STN1_2 PF09170.10 CBZ23790.1 - 0.14 12.4 0.8 0.35 11.1 0.8 1.6 1 0 0 1 1 1 0 CST, Suppressor of cdc thirteen homolog, complex subunit STN1 HR1 PF02185.16 CBZ23790.1 - 2 8.6 6.6 8.5 6.6 0.5 2.9 3 0 0 3 3 3 0 Hr1 repeat Ribosomal_L39 PF00832.20 CBZ23791.1 - 3.4e-18 65.0 15.4 3.8e-18 64.8 15.4 1.0 1 0 0 1 1 1 1 Ribosomal L39 protein Peptidase_M18 PF02127.15 CBZ23792.1 - 1.9e-159 531.1 0.0 2.1e-159 530.9 0.0 1.0 1 0 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) Peptidase_M42 PF05343.14 CBZ23792.1 - 8.2e-09 34.9 0.0 2e-06 27.0 0.0 2.2 1 1 0 1 1 1 1 M42 glutamyl aminopeptidase COQ7 PF03232.13 CBZ23793.1 - 3e-54 183.4 0.3 3.5e-54 183.2 0.3 1.0 1 0 0 1 1 1 1 Ubiquinone biosynthesis protein COQ7 NAP PF00956.18 CBZ23794.1 - 1.7e-06 27.4 3.0 0.016 14.4 0.0 3.0 1 1 2 3 3 3 3 Nucleosome assembly protein (NAP) Phage_Mu_Gam PF07352.12 CBZ23794.1 - 0.11 12.4 0.0 0.18 11.7 0.0 1.3 1 1 0 1 1 1 0 Bacteriophage Mu Gam like protein NRN1 PF15056.6 CBZ23795.1 - 0.087 12.9 0.3 0.35 11.0 0.2 2.0 1 1 0 1 1 1 0 Neuritin protein family DUF948 PF06103.11 CBZ23795.1 - 0.12 12.7 0.7 2.1 8.6 0.0 2.9 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) Pkinase PF00069.25 CBZ23796.1 - 3.1e-55 187.4 0.0 5.5e-55 186.6 0.0 1.4 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ23796.1 - 1e-34 120.0 0.0 1.7e-34 119.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 CBZ23796.1 - 1.2e-05 24.4 0.4 0.0032 16.5 0.0 2.9 3 0 0 3 3 3 1 Haspin like kinase domain Pkinase_fungal PF17667.1 CBZ23796.1 - 6.7e-05 21.8 0.0 0.00012 21.0 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 CBZ23796.1 - 0.0004 20.4 0.0 0.12 12.2 0.0 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family Ig_6 PF18452.1 CBZ23796.1 - 0.052 13.1 0.1 0.17 11.5 0.1 1.7 2 0 0 2 2 2 0 Immunoglobulin domain ECH_1 PF00378.20 CBZ23797.1 - 4.6e-74 248.9 0.7 5.3e-74 248.7 0.7 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 CBZ23797.1 - 2.4e-35 122.6 0.9 4.5e-32 111.9 0.1 2.0 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase Peptidase_S49 PF01343.18 CBZ23797.1 - 0.011 15.7 0.0 0.16 11.9 0.0 2.3 2 0 0 2 2 2 0 Peptidase family S49 UCH PF00443.29 CBZ23798.1 - 1.9e-42 145.6 0.0 3e-42 144.9 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP_var PF17807.1 CBZ23798.1 - 2.1e-17 62.6 7.5 6.2e-16 57.9 5.5 2.6 2 0 0 2 2 2 1 Variant UBP zinc finger zf-UBP PF02148.19 CBZ23798.1 - 6.8e-16 58.4 29.2 9.3e-16 57.9 7.8 3.6 3 0 0 3 3 3 2 Zn-finger in ubiquitin-hydrolases and other protein UCH_1 PF13423.6 CBZ23798.1 - 3.2e-13 50.0 0.0 1.2e-12 48.1 0.0 2.0 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UBA PF00627.31 CBZ23798.1 - 2.3e-05 24.2 0.1 0.00014 21.7 0.2 2.3 2 0 0 2 2 2 1 UBA/TS-N domain UBA_4 PF14555.6 CBZ23798.1 - 0.12 12.2 0.0 0.26 11.1 0.0 1.5 1 0 0 1 1 1 0 UBA-like domain CUE PF02845.16 CBZ23798.1 - 0.14 11.9 0.0 0.39 10.5 0.0 1.8 1 0 0 1 1 1 0 CUE domain Acyltransferase PF01553.21 CBZ23800.1 - 1.5e-10 40.8 0.0 2.8e-10 39.9 0.0 1.4 1 0 0 1 1 1 1 Acyltransferase Phage_holin_3_3 PF16083.5 CBZ23800.1 - 0.029 14.5 1.6 0.06 13.5 1.6 1.5 1 0 0 1 1 1 0 LydA holin phage, holin superfamily III LapA_dom PF06305.11 CBZ23800.1 - 6.1 6.7 6.9 1.7 8.5 3.3 2.0 1 1 1 2 2 2 0 Lipopolysaccharide assembly protein A domain SLD5_C PF16922.5 CBZ23802.1 - 4e-09 36.5 0.0 7.9e-09 35.6 0.0 1.5 1 0 0 1 1 1 1 DNA replication complex GINS protein SLD5 C-terminus Sld5 PF05916.11 CBZ23802.1 - 0.0019 18.7 0.1 0.0037 17.7 0.1 1.5 1 0 0 1 1 1 1 GINS complex protein MCC-bdg_PDZ PF10506.9 CBZ23803.1 - 0.00082 19.3 0.2 0.00082 19.3 0.2 4.9 7 0 0 7 7 5 1 PDZ domain of MCC-2 bdg protein for Usher syndrome DHR10 PF18595.1 CBZ23803.1 - 0.0018 18.3 31.1 0.1 12.7 8.7 3.6 3 0 0 3 3 3 2 Designed helical repeat protein 10 domain DUF4407 PF14362.6 CBZ23803.1 - 0.0027 17.1 9.4 0.0027 17.1 9.4 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF4407) Tropomyosin PF00261.20 CBZ23803.1 - 0.0086 15.5 22.4 0.015 14.7 3.4 3.4 3 0 0 3 3 3 2 Tropomyosin DUF4600 PF15372.6 CBZ23803.1 - 0.0099 16.3 7.2 1.2 9.5 2.1 2.8 2 0 0 2 2 2 2 Domain of unknown function (DUF4600) Phage_GP20 PF06810.11 CBZ23803.1 - 0.013 15.3 4.2 0.013 15.3 4.2 3.2 4 0 0 4 4 4 0 Phage minor structural protein GP20 APG6_N PF17675.1 CBZ23803.1 - 0.03 14.9 34.7 0.16 12.5 8.6 4.3 4 0 0 4 4 4 0 Apg6 coiled-coil region TPR_MLP1_2 PF07926.12 CBZ23803.1 - 0.032 14.3 30.9 0.78 9.8 2.8 3.6 3 0 0 3 3 3 0 TPR/MLP1/MLP2-like protein ADIP PF11559.8 CBZ23803.1 - 0.056 13.5 27.5 0.33 11.0 2.3 3.4 3 0 0 3 3 3 0 Afadin- and alpha -actinin-Binding ATG16 PF08614.11 CBZ23803.1 - 0.14 12.4 30.9 0.68 10.1 11.5 4.1 2 1 1 3 3 3 0 Autophagy protein 16 (ATG16) Uso1_p115_C PF04871.13 CBZ23803.1 - 0.16 12.4 28.1 2.1 8.7 0.6 4.5 4 0 0 4 4 4 0 Uso1 / p115 like vesicle tethering protein, C terminal region Asparaginase_2 PF01112.18 CBZ23803.1 - 0.18 10.8 3.5 0.13 11.2 0.7 2.1 2 0 0 2 2 2 0 Asparaginase Myc-LZ PF02344.15 CBZ23803.1 - 0.19 11.8 0.0 0.19 11.8 0.0 3.0 3 0 0 3 3 3 0 Myc leucine zipper domain FH2 PF02181.23 CBZ23803.1 - 0.33 10.0 6.7 4.9 6.2 0.2 3.2 3 0 0 3 3 3 0 Formin Homology 2 Domain TMCO5 PF14992.6 CBZ23803.1 - 0.43 10.1 8.2 0.22 11.1 4.1 2.4 2 1 0 2 2 2 0 TMCO5 family CENP-H PF05837.12 CBZ23803.1 - 0.85 10.1 17.5 0.15 12.5 3.4 3.4 3 0 0 3 3 3 0 Centromere protein H (CENP-H) FlxA PF14282.6 CBZ23803.1 - 1.2 9.2 22.2 4.8 7.2 6.9 3.8 3 0 0 3 3 3 0 FlxA-like protein DUF1640 PF07798.11 CBZ23803.1 - 1.4 9.0 19.4 0.43 10.6 0.7 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF1640) HALZ PF02183.18 CBZ23803.1 - 1.7 9.0 11.5 4.2 7.7 0.0 4.5 4 0 0 4 4 4 0 Homeobox associated leucine zipper Striatin PF08232.12 CBZ23803.1 - 2.6 8.6 15.4 0.49 11.0 10.0 2.5 3 0 0 3 3 3 0 Striatin family HIP1_clath_bdg PF16515.5 CBZ23803.1 - 2.7 8.7 24.1 1.3 9.7 1.6 3.8 3 0 0 3 3 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 DUF1664 PF07889.12 CBZ23803.1 - 2.9 7.9 9.5 2.7 8.1 1.0 4.0 5 0 0 5 5 5 0 Protein of unknown function (DUF1664) Rootletin PF15035.6 CBZ23803.1 - 3 7.8 16.9 11 6.0 13.3 3.0 2 1 1 3 3 3 0 Ciliary rootlet component, centrosome cohesion Fib_alpha PF08702.10 CBZ23803.1 - 3.6 7.8 9.8 1.5 9.0 0.8 3.4 3 0 0 3 3 3 0 Fibrinogen alpha/beta chain family YabA PF06156.13 CBZ23803.1 - 4.4 8.0 14.8 6.8 7.4 1.8 3.9 3 0 0 3 3 3 0 Initiation control protein YabA BRE1 PF08647.11 CBZ23803.1 - 4.6 7.4 19.5 0.03 14.4 6.2 3.2 3 0 0 3 3 3 0 BRE1 E3 ubiquitin ligase DUF4472 PF14739.6 CBZ23803.1 - 7.6 7.3 19.1 0.81 10.5 4.4 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4472) Fez1 PF06818.15 CBZ23803.1 - 8 6.9 23.6 2.6 8.5 13.0 3.3 2 1 1 3 3 3 0 Fez1 Rho_Binding PF08912.11 CBZ23803.1 - 8.2 7.3 19.6 1.1 10.2 0.8 3.3 3 0 0 3 3 2 0 Rho Binding Tropomyosin_1 PF12718.7 CBZ23803.1 - 8.6 6.5 23.1 0.62 10.2 5.9 3.2 3 0 0 3 3 3 0 Tropomyosin like Peptidase_M1 PF01433.20 CBZ23804.1 - 1.8e-65 220.6 0.0 2.9e-65 219.9 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M1 domain ERAP1_C PF11838.8 CBZ23804.1 - 4.2e-35 121.8 0.1 5.9e-35 121.3 0.1 1.2 1 0 0 1 1 1 1 ERAP1-like C-terminal domain Peptidase_M1_N PF17900.1 CBZ23804.1 - 3.3e-22 79.6 0.0 7.3e-22 78.5 0.0 1.6 2 0 0 2 2 2 1 Peptidase M1 N-terminal domain ApbA PF02558.16 CBZ23805.1 - 0.019 14.6 0.0 0.04 13.6 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Serine_protease PF18405.1 CBZ23805.1 - 0.038 13.1 0.2 0.16 11.1 0.1 1.8 2 0 0 2 2 2 0 Gammaproteobacterial serine protease LRR_9 PF14580.6 CBZ23807.1 - 1.5e-18 66.9 0.3 2.3e-18 66.3 0.3 1.2 1 0 0 1 1 1 1 Leucine-rich repeat LRR_4 PF12799.7 CBZ23807.1 - 3.2e-12 46.4 4.2 4.3e-05 23.8 0.4 3.6 2 1 2 4 4 4 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CBZ23807.1 - 2.8e-08 33.4 2.8 4.9e-07 29.4 0.6 3.1 2 2 0 3 3 3 1 Leucine rich repeat LRR_6 PF13516.6 CBZ23807.1 - 0.0028 17.6 2.4 2.5 8.4 0.1 3.4 3 0 0 3 3 3 2 Leucine Rich repeat Herpes_pp85 PF04637.12 CBZ23807.1 - 0.21 10.0 1.0 0.32 9.3 1.0 1.2 1 0 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) LRR_1 PF00560.33 CBZ23807.1 - 0.47 11.2 5.4 2.1e+02 3.1 0.0 4.6 3 1 1 4 4 4 0 Leucine Rich Repeat Dynamin_M PF01031.20 CBZ23808.1 - 2.9e-82 276.1 0.4 6.2e-82 275.0 0.4 1.5 1 0 0 1 1 1 1 Dynamin central region Dynamin_N PF00350.23 CBZ23808.1 - 3.8e-51 173.5 0.3 2.4e-50 170.9 0.0 2.2 2 0 0 2 2 2 1 Dynamin family GED PF02212.18 CBZ23808.1 - 2.1e-25 88.7 0.6 7.5e-25 86.9 0.6 2.0 1 0 0 1 1 1 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.23 CBZ23808.1 - 8.2e-05 22.7 0.3 0.00099 19.2 0.3 2.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase AF0941-like PF14591.6 CBZ23808.1 - 0.012 16.2 1.7 3.6 8.2 0.6 3.2 2 1 0 2 2 2 0 AF0941-like p450 PF00067.22 CBZ23808.1 - 0.012 14.4 0.6 0.023 13.5 0.0 1.7 2 0 0 2 2 2 0 Cytochrome P450 FeoB_N PF02421.18 CBZ23808.1 - 0.018 14.6 0.2 4.2 6.9 0.0 2.8 2 0 0 2 2 2 0 Ferrous iron transport protein B Baculo_p74 PF04583.12 CBZ23808.1 - 0.03 13.8 0.0 0.066 12.7 0.0 1.5 1 0 0 1 1 1 0 Baculoviridae p74 conserved region AAA_15 PF13175.6 CBZ23808.1 - 0.074 12.7 1.5 0.58 9.8 0.0 2.7 3 0 0 3 3 3 0 AAA ATPase domain SBDS PF01172.18 CBZ23808.1 - 0.15 12.2 0.0 0.32 11.1 0.0 1.5 1 0 0 1 1 1 0 Shwachman-Bodian-Diamond syndrome (SBDS) protein Apo-CIII PF05778.12 CBZ23808.1 - 0.25 11.0 0.8 0.68 9.6 0.2 2.0 2 0 0 2 2 2 0 Apolipoprotein CIII (Apo-CIII) DUF4379 PF14311.6 CBZ23810.1 - 1.4e-43 147.1 14.8 9.8e-16 57.9 2.3 3.4 3 0 0 3 3 3 3 Probable Zinc-ribbon domain Zn-ribbon_8 PF09723.10 CBZ23810.1 - 6.4e-05 23.0 9.6 0.49 10.5 0.1 3.6 3 0 0 3 3 3 3 Zinc ribbon domain zf-C3HC4_3 PF13920.6 CBZ23810.1 - 4.5 7.2 15.5 8.1 6.4 1.9 3.9 4 1 0 4 4 4 0 Zinc finger, C3HC4 type (RING finger) DTW PF03942.15 CBZ23811.1 - 4.1e-31 108.3 0.0 7.2e-31 107.4 0.0 1.4 1 0 0 1 1 1 1 DTW domain GDI PF00996.18 CBZ23812.1 - 3.4e-180 599.2 0.0 3.9e-180 599.0 0.0 1.0 1 0 0 1 1 1 1 GDP dissociation inhibitor YodL PF14191.6 CBZ23812.1 - 0.013 16.3 0.2 0.42 11.5 0.0 2.6 2 0 0 2 2 2 0 YodL-like Pkinase PF00069.25 CBZ23813.1 - 1e-36 126.7 0.0 1.4e-35 122.9 0.0 2.4 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ23813.1 - 3.1e-15 56.2 0.0 7.3e-15 54.9 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CBZ23813.1 - 0.091 12.1 0.0 1.2 8.4 0.0 2.3 2 1 0 2 2 2 0 Kinase-like ERG2_Sigma1R PF04622.12 CBZ23814.1 - 1.1e-79 266.6 0.4 1.3e-79 266.4 0.4 1.0 1 0 0 1 1 1 1 ERG2 and Sigma1 receptor like protein LRR_4 PF12799.7 CBZ23815.1 - 3.4e-10 40.0 12.8 0.017 15.5 0.2 5.8 3 2 3 6 6 6 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CBZ23815.1 - 1.3e-07 31.2 10.8 0.027 14.2 1.3 4.9 3 2 3 6 6 6 5 Leucine rich repeat LRR_6 PF13516.6 CBZ23815.1 - 8.4e-06 25.4 2.9 5.1 7.4 0.0 6.9 7 0 0 7 7 7 1 Leucine Rich repeat FNIP PF05725.12 CBZ23815.1 - 0.00012 22.2 6.0 0.39 10.9 0.1 4.7 5 0 0 5 5 5 2 FNIP Repeat LRR_1 PF00560.33 CBZ23815.1 - 0.005 17.2 14.7 13 6.8 0.5 7.4 6 2 0 6 6 6 1 Leucine Rich Repeat VIT1 PF01988.19 CBZ23816.1 - 5.4e-11 42.8 0.0 5.4e-11 42.8 0.0 2.8 2 1 1 3 3 3 2 VIT family Glyco_transf_24 PF18404.1 CBZ23817.1 - 2.6e-131 436.9 2.4 3.6e-131 436.4 2.4 1.2 1 0 0 1 1 1 1 Glucosyltransferase 24 Thioredoxin_14 PF18402.1 CBZ23817.1 - 2.4e-35 122.7 0.1 1.9e-32 113.2 0.0 2.9 3 0 0 3 3 3 2 Thioredoxin-like domain Thioredoxin_13 PF18401.1 CBZ23817.1 - 4e-22 78.6 0.2 1.1e-20 74.0 0.0 2.9 3 0 0 3 3 3 1 Thioredoxin-like domain UDP-g_GGTase PF06427.11 CBZ23817.1 - 2.9e-13 49.9 0.0 6.3e-13 48.8 0.0 1.6 1 0 0 1 1 1 1 UDP-glucose:Glycoprotein Glucosyltransferase Thioredoxin_12 PF18400.1 CBZ23817.1 - 1.7e-12 47.6 0.0 4.3e-12 46.3 0.0 1.7 1 0 0 1 1 1 1 Thioredoxin-like domain Glyco_transf_8 PF01501.20 CBZ23817.1 - 4.8e-07 29.6 0.3 9.6e-07 28.6 0.3 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 8 DUF4139 PF13598.6 CBZ23818.1 - 3.8e-34 118.2 0.0 5.4e-34 117.7 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4139) AAA_12 PF13087.6 CBZ23819.1 - 1.5e-32 112.9 0.0 2.7e-32 112.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 CBZ23819.1 - 5.4e-15 55.9 0.1 1.8e-09 37.8 0.1 2.6 2 0 0 2 2 2 2 AAA domain AAA_30 PF13604.6 CBZ23819.1 - 1.1e-06 28.5 4.6 0.0014 18.4 0.0 3.3 4 0 0 4 4 4 2 AAA domain AAA_19 PF13245.6 CBZ23819.1 - 3.8e-06 27.3 0.2 0.2 12.0 0.3 3.5 2 1 0 2 2 2 2 AAA domain PhoH PF02562.16 CBZ23819.1 - 0.0034 16.9 0.0 0.2 11.1 0.0 2.9 3 0 0 3 3 3 1 PhoH-like protein AAA_22 PF13401.6 CBZ23819.1 - 0.0037 17.6 0.6 1.1 9.6 0.0 3.9 4 1 0 4 4 4 1 AAA domain zf-C2H2_10 PF16588.5 CBZ23819.1 - 0.01 15.6 5.1 0.018 14.8 5.1 1.4 1 0 0 1 1 1 0 C2H2 zinc-finger AAA_33 PF13671.6 CBZ23819.1 - 0.014 15.5 0.1 5.4 7.2 0.0 3.3 2 0 0 2 2 2 0 AAA domain Viral_helicase1 PF01443.18 CBZ23819.1 - 0.015 15.0 0.9 5.4 6.7 0.0 3.2 3 0 0 3 3 3 0 Viral (Superfamily 1) RNA helicase DUF2075 PF09848.9 CBZ23819.1 - 0.017 14.3 0.2 0.04 13.2 0.0 1.7 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) adh_short PF00106.25 CBZ23820.1 - 5e-05 22.8 0.0 0.0027 17.2 0.1 2.9 2 1 0 2 2 2 1 short chain dehydrogenase DUF4197 PF13852.6 CBZ23821.1 - 0.12 12.1 4.0 0.12 12.0 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4197) Gpi1 PF05024.15 CBZ23825.1 - 2.4e-40 138.6 1.4 5.5e-40 137.5 1.4 1.6 1 0 0 1 1 1 1 N-acetylglucosaminyl transferase component (Gpi1) Pkinase PF00069.25 CBZ23826.1 - 1.5e-73 247.4 0.0 2e-73 247.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ23826.1 - 8.6e-40 136.6 0.0 1.2e-39 136.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CBZ23826.1 - 1.3e-06 28.0 0.0 7.4e-06 25.5 0.0 1.9 1 1 1 2 2 2 1 Kinase-like RIO1 PF01163.22 CBZ23826.1 - 2.8e-05 23.8 0.3 0.00067 19.3 0.0 2.1 1 1 1 2 2 2 1 RIO1 family Kdo PF06293.14 CBZ23826.1 - 0.00013 21.4 0.1 0.00023 20.6 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 CBZ23826.1 - 0.00062 18.8 0.1 0.001 18.1 0.1 1.3 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 CBZ23826.1 - 0.0021 18.0 0.3 0.15 11.9 0.1 2.9 3 0 0 3 3 3 1 Phosphotransferase enzyme family PPR_2 PF13041.6 CBZ23827.1 - 3.4e-06 27.1 0.0 0.01 16.0 0.0 4.1 4 1 1 5 5 5 2 PPR repeat family PPR_3 PF13812.6 CBZ23827.1 - 0.0013 18.8 0.0 1.6 8.9 0.0 3.5 2 1 1 3 3 3 1 Pentatricopeptide repeat domain PPR PF01535.20 CBZ23827.1 - 0.0018 18.4 0.0 9.6 6.7 0.0 4.3 5 0 0 5 5 5 1 PPR repeat SPG48 PF14764.6 CBZ23827.1 - 0.015 15.8 0.6 0.66 10.5 0.2 2.5 2 0 0 2 2 2 0 AP-5 complex subunit, vesicle trafficking TPR_14 PF13428.6 CBZ23827.1 - 3.3 8.8 5.8 17 6.6 0.1 4.9 5 2 2 7 7 7 0 Tetratricopeptide repeat Methyltr_RsmB-F PF01189.17 CBZ23828.1 - 5.7e-18 65.3 0.1 1.8e-08 34.3 0.0 3.5 3 0 0 3 3 3 3 16S rRNA methyltransferase RsmB/F FtsJ PF01728.19 CBZ23828.1 - 0.049 13.7 0.0 0.47 10.5 0.0 2.1 2 0 0 2 2 2 0 FtsJ-like methyltransferase LcrG PF07216.12 CBZ23830.1 - 0.081 12.8 0.5 0.23 11.4 0.5 1.7 1 0 0 1 1 1 0 LcrG protein BatA PF07584.11 CBZ23831.1 - 1.3 9.5 5.9 2.2 8.7 3.8 2.6 2 0 0 2 2 2 0 Aerotolerance regulator N-terminal Fumerase PF05681.14 CBZ23833.1 - 1.8e-38 132.5 0.0 2.3e-38 132.2 0.0 1.1 1 0 0 1 1 1 1 Fumarate hydratase (Fumerase) PPTA PF01239.22 CBZ23834.1 - 8e-17 60.4 13.8 5.5e-07 29.1 0.3 5.5 5 0 0 5 5 5 5 Protein prenyltransferase alpha subunit repeat DUF4219 PF13961.6 CBZ23834.1 - 4.2 7.1 6.9 27 4.6 0.1 3.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4219) EF-hand_7 PF13499.6 CBZ23836.1 - 8.1e-13 48.6 0.1 0.0035 17.7 0.0 4.5 4 0 0 4 4 4 3 EF-hand domain pair EF-hand_6 PF13405.6 CBZ23836.1 - 0.00042 20.0 0.2 0.75 9.9 0.0 3.9 4 0 0 4 4 4 1 EF-hand domain EF-hand_1 PF00036.32 CBZ23836.1 - 0.0018 17.7 0.3 0.41 10.3 0.1 3.6 4 0 0 4 4 4 1 EF hand Zn_ribbon_recom PF13408.6 CBZ23839.1 - 0.13 12.8 1.7 0.26 11.8 1.7 1.4 1 0 0 1 1 1 0 Recombinase zinc beta ribbon domain Rad50_zn_hook PF04423.14 CBZ23839.1 - 0.29 11.0 2.1 0.24 11.3 0.3 1.8 2 0 0 2 2 2 0 Rad50 zinc hook motif zf-C2H2 PF00096.26 CBZ23839.1 - 2 9.0 5.0 5.3 7.7 5.0 1.8 1 0 0 1 1 1 0 Zinc finger, C2H2 type DnaJ PF00226.31 CBZ23840.1 - 7.7e-08 32.4 0.0 1.9e-07 31.1 0.0 1.6 1 0 0 1 1 1 1 DnaJ domain zf_C2H2_10 PF18414.1 CBZ23842.1 - 0.017 14.6 0.0 0.025 14.1 0.0 1.2 1 0 0 1 1 1 0 C2H2 type zinc-finger zf-C2H2_12 PF18658.1 CBZ23842.1 - 0.1 12.2 0.0 0.18 11.4 0.0 1.4 1 0 0 1 1 1 0 Zinc-finger C2H2-type zf-met2 PF12907.7 CBZ23842.1 - 0.15 12.2 2.4 1.2 9.4 2.4 2.3 1 1 0 1 1 1 0 Zinc-binding PIH1_CS PF18201.1 CBZ23844.1 - 3.9e-09 36.8 0.0 6e-09 36.2 0.0 1.3 1 0 0 1 1 1 1 PIH1 CS-like domain Snapin_Pallidin PF14712.6 CBZ23845.1 - 0.022 15.2 24.4 0.45 11.0 0.8 4.7 1 1 3 4 4 4 0 Snapin/Pallidin PIN_8 PF18476.1 CBZ23845.1 - 0.038 13.8 12.9 0.49 10.2 2.4 2.3 1 1 1 2 2 2 0 PIN like domain Sugarporin_N PF11471.8 CBZ23845.1 - 0.053 13.5 7.5 1.2 9.2 1.4 3.3 1 1 1 2 2 2 0 Maltoporin periplasmic N-terminal extension XPG_N PF00752.17 CBZ23845.1 - 0.1 13.0 0.0 0.29 11.6 0.0 1.7 1 0 0 1 1 1 0 XPG N-terminal domain DUF1664 PF07889.12 CBZ23845.1 - 0.15 12.1 16.1 0.1 12.6 3.5 3.5 2 2 1 3 3 3 0 Protein of unknown function (DUF1664) DOG1 PF14144.6 CBZ23845.1 - 0.37 11.0 8.1 0.19 12.0 0.8 3.6 3 1 1 4 4 4 0 Seed dormancy control FlaC_arch PF05377.11 CBZ23845.1 - 0.39 11.2 8.8 2 8.9 0.1 4.5 4 1 1 6 6 6 0 Flagella accessory protein C (FlaC) DUF2730 PF10805.8 CBZ23845.1 - 0.91 9.7 8.1 6.4 6.9 0.3 3.7 1 1 3 4 4 4 0 Protein of unknown function (DUF2730) Baculo_PEP_C PF04513.12 CBZ23845.1 - 2.6 8.1 11.9 0.13 12.3 0.3 3.1 1 1 2 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus FapA PF03961.13 CBZ23845.1 - 3.2 6.3 12.4 2.4 6.7 1.1 2.2 1 1 1 2 2 2 0 Flagellar Assembly Protein A TolA_bind_tri PF16331.5 CBZ23845.1 - 3.4 7.8 33.9 3.3 7.9 4.5 4.8 2 1 2 4 4 3 0 TolA binding protein trimerisation Baculo_F PF12259.8 CBZ23845.1 - 3.6 6.0 6.9 5.8 5.3 4.5 1.9 1 1 1 2 2 2 0 Baculovirus F protein DUF1993 PF09351.10 CBZ23845.1 - 6.8 6.8 7.8 3.6 7.7 3.1 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF1993) XhlA PF10779.9 CBZ23845.1 - 9.3 6.5 7.3 2.8 8.2 0.5 3.2 2 2 1 3 3 3 0 Haemolysin XhlA Plasmid_RAQPRD PF09686.10 CBZ23845.1 - 9.5 6.5 21.5 0.063 13.5 1.2 4.4 3 2 1 4 4 4 0 Plasmid protein of unknown function (Plasmid_RAQPRD) Pyr_redox_2 PF07992.14 CBZ23846.1 - 2e-45 155.3 0.1 2.7e-45 154.8 0.1 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 CBZ23846.1 - 1.9e-20 73.2 1.0 6.4e-17 61.9 0.0 2.6 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 CBZ23846.1 - 8.6e-20 71.0 0.1 2.5e-19 69.5 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain FAD_oxidored PF12831.7 CBZ23846.1 - 6.3e-10 39.0 0.1 1.2e-09 38.1 0.1 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.14 CBZ23846.1 - 8.4e-07 28.0 1.4 0.00035 19.4 0.5 3.2 3 0 0 3 3 3 2 HI0933-like protein FAD_binding_3 PF01494.19 CBZ23846.1 - 1.7e-06 27.6 0.1 0.021 14.1 0.0 3.2 3 0 0 3 3 3 2 FAD binding domain GIDA PF01134.22 CBZ23846.1 - 3.2e-06 26.5 2.1 0.015 14.4 0.2 3.3 4 0 0 4 4 4 2 Glucose inhibited division protein A Pyr_redox_3 PF13738.6 CBZ23846.1 - 3.9e-06 26.4 11.3 0.003 16.8 1.6 3.5 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 CBZ23846.1 - 1.7e-05 24.2 0.0 0.00022 20.5 0.0 2.4 2 1 1 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) AlaDh_PNT_C PF01262.21 CBZ23846.1 - 8.5e-05 21.9 0.1 0.15 11.3 0.1 2.4 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain Thi4 PF01946.17 CBZ23846.1 - 8.9e-05 21.8 0.9 0.011 15.1 0.1 2.3 2 0 0 2 2 2 1 Thi4 family DAO PF01266.24 CBZ23846.1 - 0.00013 21.7 7.7 0.012 15.2 0.7 3.2 3 1 0 4 4 4 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 CBZ23846.1 - 0.00042 19.5 1.7 0.00042 19.5 1.7 2.8 2 1 0 3 3 3 1 FAD binding domain ThiF PF00899.21 CBZ23846.1 - 0.0008 18.8 0.0 0.0017 17.8 0.0 1.5 1 0 0 1 1 1 1 ThiF family NAD_binding_8 PF13450.6 CBZ23846.1 - 0.00082 19.6 4.8 0.086 13.1 0.8 2.5 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 CBZ23846.1 - 0.0035 16.5 0.5 0.36 9.8 0.3 2.2 2 0 0 2 2 2 1 Lycopene cyclase protein 2-Hacid_dh_C PF02826.19 CBZ23846.1 - 0.0059 16.0 0.1 0.039 13.3 0.0 2.1 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 3HCDH_N PF02737.18 CBZ23846.1 - 0.0065 16.4 0.0 0.013 15.4 0.0 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 CBZ23846.1 - 0.11 12.6 0.0 0.26 11.4 0.0 1.6 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Bac_surface_Ag PF01103.23 CBZ23847.1 - 3.1e-20 72.9 0.5 4e-20 72.6 0.5 1.2 1 0 0 1 1 1 1 Surface antigen Folliculin PF11704.8 CBZ23848.1 - 2e-08 34.3 0.6 3.9e-08 33.4 0.0 1.8 2 1 0 2 2 2 1 Vesicle coat protein involved in Golgi to plasma membrane transport Folliculin_C PF16692.5 CBZ23848.1 - 2.9e-08 33.7 0.0 5.1e-08 32.9 0.0 1.4 1 0 0 1 1 1 1 Folliculin C-terminal domain Ribosomal_S8 PF00410.19 CBZ23849.1 - 5.4e-21 74.9 0.0 6.8e-21 74.5 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S8 BRCT PF00533.26 CBZ23850.1 - 2.2e-09 37.5 0.0 0.045 14.1 0.0 4.5 4 0 0 4 4 4 3 BRCA1 C Terminus (BRCT) domain RTT107_BRCT_5 PF16770.5 CBZ23850.1 - 1.2e-07 31.5 0.0 9e-07 28.7 0.0 2.5 3 0 0 3 3 3 1 Regulator of Ty1 transposition protein 107 BRCT domain PTCB-BRCT PF12738.7 CBZ23850.1 - 4.5e-06 26.5 1.1 0.6 10.1 0.0 5.1 5 1 0 5 5 5 2 twin BRCT domain BRCT_2 PF16589.5 CBZ23850.1 - 1.1e-05 25.8 0.0 0.59 10.6 0.0 3.4 3 0 0 3 3 3 2 BRCT domain, a BRCA1 C-terminus domain BRCT_3 PF18428.1 CBZ23850.1 - 0.0029 17.6 2.2 2.5 8.2 0.1 3.9 4 0 0 4 4 4 1 BRCA1 C Terminus (BRCT) domain DUF2795 PF11387.8 CBZ23850.1 - 0.12 12.6 0.0 6 7.2 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2795) Diphthamide_syn PF01866.17 CBZ23851.1 - 1.8e-112 375.7 0.0 2.3e-112 375.4 0.0 1.1 1 0 0 1 1 1 1 Putative diphthamide synthesis protein Flagellar_rod PF05149.12 CBZ23852.1 - 8.9e-103 343.7 29.0 8.9e-103 343.7 29.0 2.8 2 1 1 3 3 3 2 Paraflagellar rod protein DUF1120 PF06551.12 CBZ23852.1 - 0.13 12.5 0.9 0.26 11.4 0.9 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1120) Pox_A_type_inc PF04508.12 CBZ23852.1 - 6 6.9 8.0 1.2 9.1 0.2 3.5 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat Flagellar_rod PF05149.12 CBZ23853.1 - 8.9e-103 343.7 29.0 8.9e-103 343.7 29.0 2.8 2 1 1 3 3 3 2 Paraflagellar rod protein DUF1120 PF06551.12 CBZ23853.1 - 0.13 12.4 0.9 0.26 11.4 0.9 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1120) Pox_A_type_inc PF04508.12 CBZ23853.1 - 6 6.9 8.0 1.2 9.1 0.2 3.5 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat Histone_H2A_C PF16211.5 CBZ23854.1 - 1.5e-07 31.0 0.7 3.2e-07 30.0 0.7 1.6 1 0 0 1 1 1 1 C-terminus of histone H2A Histone PF00125.24 CBZ23854.1 - 1.9e-06 28.2 0.0 2.9e-06 27.7 0.0 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 CBZ23854.1 - 0.035 14.4 0.0 0.071 13.4 0.0 1.5 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone_H2A_C PF16211.5 CBZ23855.1 - 1.5e-07 31.0 0.7 3.2e-07 30.0 0.7 1.6 1 0 0 1 1 1 1 C-terminus of histone H2A Histone PF00125.24 CBZ23855.1 - 1.9e-06 28.2 0.0 2.9e-06 27.7 0.0 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 CBZ23855.1 - 0.035 14.4 0.0 0.071 13.4 0.0 1.5 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone_H2A_C PF16211.5 CBZ23856.1 - 1.5e-07 31.0 0.7 3.2e-07 30.0 0.7 1.6 1 0 0 1 1 1 1 C-terminus of histone H2A Histone PF00125.24 CBZ23856.1 - 1.9e-06 28.2 0.0 2.9e-06 27.7 0.0 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 CBZ23856.1 - 0.035 14.4 0.0 0.071 13.4 0.0 1.5 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone MutS_III PF05192.18 CBZ23857.1 - 2.5e-16 60.5 0.0 5.6e-16 59.3 0.0 1.6 1 1 0 1 1 1 1 MutS domain III MutS_V PF00488.21 CBZ23857.1 - 5.4e-15 55.9 2.2 9.1e-08 32.3 0.2 2.8 3 0 0 3 3 3 2 MutS domain V AAA_29 PF13555.6 CBZ23857.1 - 0.011 15.5 0.0 0.023 14.4 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_30 PF13604.6 CBZ23857.1 - 0.012 15.3 0.0 0.028 14.1 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.6 CBZ23857.1 - 0.074 13.4 0.0 0.23 11.8 0.0 1.9 1 0 0 1 1 1 0 AAA ATPase domain AAA_27 PF13514.6 CBZ23857.1 - 0.089 12.4 0.0 0.23 11.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain MORN PF02493.20 CBZ23858.1 - 4.4e-46 152.1 106.4 1.4e-06 27.8 1.9 21.8 22 0 0 22 22 22 18 MORN repeat IHABP4_N PF16174.5 CBZ23858.1 - 2.8 8.5 6.0 1 9.9 2.1 2.2 2 0 0 2 2 2 0 Intracellular hyaluronan-binding protein 4 N-terminal 4HBT PF03061.22 CBZ23859.1 - 1.5e-14 54.0 4.6 2.1e-09 37.6 0.7 2.6 2 0 0 2 2 2 2 Thioesterase superfamily 4HBT_2 PF13279.6 CBZ23859.1 - 0.016 15.7 1.0 2.8 8.5 0.2 2.7 1 1 1 2 2 2 0 Thioesterase-like superfamily Cas_Csx8 PF09657.10 CBZ23859.1 - 0.044 12.8 0.4 0.068 12.2 0.4 1.2 1 0 0 1 1 1 0 CRISPR-associated protein Csx8 (Cas_Csx8) RACo_linker PF17650.1 CBZ23859.1 - 0.13 12.2 0.1 0.31 10.9 0.1 1.6 1 0 0 1 1 1 0 RACo linker region CENP-F_leu_zip PF10473.9 CBZ23860.1 - 0.063 13.3 2.9 0.12 12.4 2.9 1.5 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Thioredoxin PF00085.20 CBZ23861.1 - 1.3e-06 28.3 0.0 1.7e-06 27.9 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin ABC_tran PF00005.27 CBZ23862.1 - 1.2e-26 93.8 0.0 2.2e-26 93.0 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 CBZ23862.1 - 8.6e-07 29.1 1.0 0.0002 21.3 0.1 2.2 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 CBZ23862.1 - 0.00068 19.1 0.1 0.0032 16.9 0.1 1.9 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 CBZ23862.1 - 0.036 14.0 0.0 0.062 13.2 0.0 1.3 1 0 0 1 1 1 0 RsgA GTPase IstB_IS21 PF01695.17 CBZ23862.1 - 0.042 13.6 0.0 4 7.1 0.0 2.2 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_16 PF13191.6 CBZ23862.1 - 0.044 14.1 0.0 0.088 13.2 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain T6SS_VipA PF05591.12 CBZ23862.1 - 0.051 13.4 0.1 0.086 12.6 0.1 1.3 1 0 0 1 1 1 0 Type VI secretion system, VipA, VC_A0107 or Hcp2 RuvB_N PF05496.12 CBZ23862.1 - 0.056 13.2 0.1 0.11 12.2 0.1 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_10 PF12846.7 CBZ23862.1 - 0.065 12.1 0.0 6.7 5.5 0.0 2.2 2 0 0 2 2 2 0 AAA-like domain SbcCD_C PF13558.6 CBZ23862.1 - 0.076 13.3 0.4 1.1 9.6 0.4 2.4 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit T2SSE PF00437.20 CBZ23862.1 - 0.094 11.8 0.1 0.15 11.1 0.1 1.5 1 1 0 1 1 1 0 Type II/IV secretion system protein AAA_29 PF13555.6 CBZ23862.1 - 0.1 12.4 0.1 0.25 11.1 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain RINGv PF12906.7 CBZ23863.1 - 7e-11 42.1 10.6 7.2e-11 42.0 9.2 1.8 2 0 0 2 2 2 1 RING-variant domain zf-RING_2 PF13639.6 CBZ23863.1 - 0.073 13.4 7.9 0.15 12.5 7.9 1.5 1 0 0 1 1 1 0 Ring finger domain Phage_holin_2_4 PF16082.5 CBZ23863.1 - 0.68 9.7 2.5 0.81 9.5 0.3 2.2 2 0 0 2 2 2 0 Bacteriophage holin family, superfamily II-like zf-RING-like PF08746.11 CBZ23863.1 - 2.6 8.4 7.1 4.5 7.7 7.1 1.4 1 0 0 1 1 1 0 RING-like domain dsrm PF00035.26 CBZ23864.1 - 8.1e-09 36.1 0.0 0.98 10.2 0.0 5.8 5 0 0 5 5 5 4 Double-stranded RNA binding motif SYS1 PF09801.9 CBZ23865.1 - 3.8e-21 75.8 1.5 8.2e-19 68.2 0.4 2.2 2 0 0 2 2 2 2 Integral membrane protein S linking to the trans Golgi network EMP70 PF02990.16 CBZ23867.1 - 5.8e-150 500.4 16.1 7.1e-150 500.1 16.1 1.1 1 0 0 1 1 1 1 Endomembrane protein 70 Adeno_GP19K PF04881.13 CBZ23867.1 - 1.1 9.3 4.5 0.41 10.6 0.2 2.3 2 0 0 2 2 2 0 Adenovirus GP19K XPC-binding PF09280.11 CBZ23870.1 - 1.7e-06 27.7 3.3 3.1e-06 26.8 3.3 1.5 1 0 0 1 1 1 1 XPC-binding domain UBA PF00627.31 CBZ23870.1 - 2.3e-06 27.4 0.0 8e-06 25.7 0.0 2.0 1 0 0 1 1 1 1 UBA/TS-N domain MmoB_DmpM PF02406.17 CBZ23870.1 - 0.093 13.0 0.3 13 6.1 0.1 2.7 3 0 0 3 3 3 0 MmoB/DmpM family RXT2_N PF08595.11 CBZ23870.1 - 4.9 7.2 6.4 8.4 6.4 2.1 2.3 2 0 0 2 2 2 0 RXT2-like, N-terminal Cwf_Cwc_15 PF04889.12 CBZ23870.1 - 5.1 6.8 9.4 0.22 11.3 1.7 2.1 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein WD40 PF00400.32 CBZ23871.1 - 0.00018 22.2 0.0 0.15 13.0 0.0 2.8 2 0 0 2 2 2 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBZ23871.1 - 0.00018 21.7 0.0 0.011 16.0 0.0 2.6 2 1 1 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain Peptidase_M20 PF01546.28 CBZ23872.1 - 7.9e-37 127.0 0.1 1e-36 126.6 0.1 1.1 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 CBZ23872.1 - 7.2e-19 67.7 0.0 1.2e-18 67.0 0.0 1.3 1 0 0 1 1 1 1 Peptidase dimerisation domain RabGAP-TBC PF00566.18 CBZ23873.1 - 2e-43 148.6 0.0 2.8e-43 148.1 0.0 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain DUF3135 PF11333.8 CBZ23873.1 - 0.013 15.7 2.3 0.023 14.9 2.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3135) TMEM156 PF15106.6 CBZ23876.1 - 0.18 11.2 0.1 0.36 10.2 0.1 1.4 1 0 0 1 1 1 0 TMEM156 protein family MFS_1 PF07690.16 CBZ23877.1 - 5.4e-17 61.8 34.3 8.1e-14 51.3 17.5 2.7 2 1 0 2 2 2 2 Major Facilitator Superfamily Nodulin-like PF06813.13 CBZ23877.1 - 2.9e-12 46.6 17.8 2.9e-12 46.6 17.8 2.5 2 1 0 2 2 2 1 Nodulin-like BCLP PF12304.8 CBZ23877.1 - 0.21 11.1 4.3 0.13 11.8 0.4 2.4 2 0 0 2 2 2 0 Beta-casein like protein Nodulin-like PF06813.13 CBZ23878.1 - 8.2e-09 35.3 15.9 1.1e-08 34.9 12.0 2.9 2 1 0 2 2 2 1 Nodulin-like DUF819 PF05684.12 CBZ23878.1 - 0.0016 17.6 5.2 0.0059 15.7 0.2 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF819) Asn_synthase PF00733.21 CBZ23879.1 - 3.1e-15 56.7 0.4 7.6e-06 25.8 0.7 3.8 3 1 0 3 3 3 2 Asparagine synthase Ank_2 PF12796.7 CBZ23881.1 - 2.6e-05 24.7 0.2 7.8e-05 23.2 0.0 1.8 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 CBZ23881.1 - 0.0071 16.7 0.4 1.9 8.9 0.3 2.6 1 1 0 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 CBZ23881.1 - 0.011 16.3 0.2 0.11 13.1 0.1 2.5 1 1 1 2 2 2 0 Ankyrin repeats (many copies) Ank_3 PF13606.6 CBZ23881.1 - 0.039 14.5 1.1 5 8.0 0.0 3.2 3 0 0 3 3 3 0 Ankyrin repeat DUF533 PF04391.12 CBZ23881.1 - 0.34 10.5 4.6 0.095 12.3 0.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF533) DS PF01916.17 CBZ23882.1 - 0.45 9.7 1.6 0.74 9.0 1.6 1.3 1 0 0 1 1 1 0 Deoxyhypusine synthase PI3_PI4_kinase PF00454.27 CBZ23883.1 - 6.6e-36 124.4 0.1 1e-32 113.9 0.1 2.4 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.20 CBZ23883.1 - 1.9e-16 60.0 0.3 9.8e-16 57.7 0.2 2.0 2 0 0 2 2 2 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) DUF4135 PF13575.6 CBZ23883.1 - 0.086 12.2 0.0 0.19 11.0 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4135) Clat_adaptor_s PF01217.20 CBZ23884.1 - 3.6e-45 153.4 1.0 4.2e-45 153.2 1.0 1.1 1 0 0 1 1 1 1 Clathrin adaptor complex small chain zf-LYAR PF08790.11 CBZ23887.1 - 3.6e-14 52.4 2.4 3.6e-14 52.4 2.4 2.1 2 0 0 2 2 2 1 LYAR-type C2HC zinc finger zf_UBZ PF18439.1 CBZ23887.1 - 0.05 13.2 0.5 8.3 6.1 0.1 2.4 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger RRM_1 PF00076.22 CBZ23888.1 - 5.2e-21 74.2 0.3 7.3e-14 51.4 0.2 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CBZ23888.1 - 0.034 14.2 0.1 4.4 7.5 0.0 2.7 2 0 0 2 2 2 0 RNA recognition motif RNA_bind PF08675.11 CBZ23888.1 - 0.062 13.3 0.0 0.19 11.8 0.0 1.8 1 0 0 1 1 1 0 RNA binding domain RRM_1 PF00076.22 CBZ23890.1 - 2.4e-25 88.1 0.0 5.5e-14 51.8 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CBZ23890.1 - 0.0034 17.5 0.0 0.5 10.5 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif RRM_1 PF00076.22 CBZ23891.1 - 8.9e-24 83.1 0.0 6.1e-11 42.0 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CBZ23891.1 - 0.018 15.2 0.0 0.14 12.3 0.0 2.2 2 0 0 2 2 2 0 RNA recognition motif DUF5375 PF17345.2 CBZ23891.1 - 0.13 12.2 0.0 0.27 11.1 0.0 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5375) RRM_1 PF00076.22 CBZ23892.1 - 4.1e-23 81.0 0.0 3.7e-10 39.5 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) YjbT PF17089.5 CBZ23892.1 - 0.058 13.4 0.3 2.8 8.0 0.0 3.0 2 0 0 2 2 2 0 Uncharacterised protein family RRM_7 PF16367.5 CBZ23892.1 - 0.06 13.5 0.0 0.19 11.9 0.0 1.8 1 0 0 1 1 1 0 RNA recognition motif DUF4682 PF15733.5 CBZ23892.1 - 5.1 7.7 6.3 30 5.2 0.2 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4682) RRM_1 PF00076.22 CBZ23893.1 - 6.1e-32 109.3 0.0 1.2e-19 69.8 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CBZ23893.1 - 9.4e-06 25.7 0.0 0.00023 21.2 0.0 2.6 2 0 0 2 2 2 1 RNA recognition motif RRM_occluded PF16842.5 CBZ23893.1 - 0.00042 20.1 0.0 0.4 10.6 0.0 2.4 2 0 0 2 2 2 2 Occluded RNA-recognition motif RRM_5 PF13893.6 CBZ23893.1 - 0.0015 18.2 0.0 0.0064 16.1 0.0 2.0 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.8 CBZ23893.1 - 0.0023 18.0 0.0 0.02 15.0 0.0 2.5 3 0 0 3 3 3 1 Limkain b1 RRM_8 PF11835.8 CBZ23893.1 - 0.01 16.1 0.0 2.4 8.5 0.0 2.8 2 1 1 3 3 3 1 RRM-like domain RRM_3 PF08777.11 CBZ23893.1 - 0.012 15.6 0.0 2.9 8.0 0.0 2.6 2 1 0 2 2 2 0 RNA binding motif Pkinase PF00069.25 CBZ23895.1 - 5e-61 206.4 0.0 4.9e-60 203.1 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ23895.1 - 4.4e-33 114.7 0.0 8.2e-24 84.3 0.0 2.5 3 0 0 3 3 3 2 Protein tyrosine kinase Kdo PF06293.14 CBZ23895.1 - 0.00036 19.9 0.2 0.00068 19.0 0.0 1.4 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 CBZ23895.1 - 0.0068 15.4 0.0 0.01 14.8 0.0 1.1 1 0 0 1 1 1 1 Haspin like kinase domain Pkinase_fungal PF17667.1 CBZ23895.1 - 0.053 12.3 0.0 0.096 11.4 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase APH PF01636.23 CBZ23895.1 - 0.068 13.1 3.1 0.2 11.5 3.1 1.9 1 1 0 1 1 1 0 Phosphotransferase enzyme family Kinase-like PF14531.6 CBZ23895.1 - 0.16 11.3 0.0 2.2 7.6 0.0 2.2 2 0 0 2 2 2 0 Kinase-like RNA_pol_Rpc34 PF05158.12 CBZ23896.1 - 1.7e-53 182.2 0.0 3.9e-52 177.7 0.0 2.5 1 1 0 1 1 1 1 RNA polymerase Rpc34 subunit TFIIE_alpha PF02002.17 CBZ23896.1 - 0.0079 16.0 0.1 0.022 14.6 0.0 1.7 1 1 1 2 2 2 1 TFIIE alpha subunit GNVR PF13807.6 CBZ23896.1 - 0.079 12.9 0.2 0.18 11.7 0.2 1.6 1 0 0 1 1 1 0 G-rich domain on putative tyrosine kinase Carn_acyltransf PF00755.20 CBZ23897.1 - 4.2e-116 388.9 0.0 5.1e-116 388.6 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase DSS1_SEM1 PF05160.13 CBZ23899.1 - 0.11 12.6 12.2 0.24 11.5 12.2 1.7 1 1 0 1 1 1 0 DSS1/SEM1 family Lipase_3 PF01764.25 CBZ23900.1 - 2.1e-23 82.7 0.0 4.6e-23 81.7 0.0 1.6 1 0 0 1 1 1 1 Lipase (class 3) MIG-14_Wnt-bd PF06664.12 CBZ23900.1 - 2.3e-07 30.4 27.7 7.9e-07 28.6 27.8 1.7 1 1 0 1 1 1 1 Wnt-binding factor required for Wnt secretion SOBP PF15279.6 CBZ23900.1 - 2.9 8.4 7.1 7.3 7.1 7.1 1.6 1 0 0 1 1 1 0 Sine oculis-binding protein AAA_2 PF07724.14 CBZ23901.1 - 1.1e-56 191.6 0.1 4.9e-54 183.0 0.0 3.1 3 0 0 3 3 3 1 AAA domain (Cdc48 subfamily) AAA_lid_9 PF17871.1 CBZ23901.1 - 1.1e-36 124.9 0.9 1.1e-36 124.9 0.9 2.8 2 0 0 2 2 2 1 AAA lid domain AAA PF00004.29 CBZ23901.1 - 1.8e-27 96.4 0.0 3.4e-15 56.6 0.0 2.9 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.9 CBZ23901.1 - 4.6e-21 74.7 0.1 4.6e-21 74.7 0.1 3.2 3 0 0 3 3 2 1 C-terminal, D2-small domain, of ClpB protein AAA_5 PF07728.14 CBZ23901.1 - 1.1e-14 54.6 0.5 3.7e-10 39.9 0.0 3.4 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) Clp_N PF02861.20 CBZ23901.1 - 5e-13 49.0 3.0 5.6e-06 26.4 1.3 3.2 2 0 0 2 2 2 2 Clp amino terminal domain, pathogenicity island component AAA_22 PF13401.6 CBZ23901.1 - 4.6e-09 36.7 0.2 0.018 15.4 0.0 4.2 2 2 0 2 2 2 2 AAA domain AAA_16 PF13191.6 CBZ23901.1 - 1.5e-08 35.2 7.4 0.001 19.5 0.1 4.5 3 3 1 4 4 3 2 AAA ATPase domain Sigma54_activat PF00158.26 CBZ23901.1 - 3.3e-08 33.4 0.1 2.7e-05 23.9 0.0 2.9 2 1 0 2 2 2 1 Sigma-54 interaction domain IstB_IS21 PF01695.17 CBZ23901.1 - 4.1e-07 29.9 0.0 0.02 14.7 0.0 2.8 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_14 PF13173.6 CBZ23901.1 - 6.8e-07 29.4 0.0 0.032 14.3 0.0 3.2 3 0 0 3 3 2 2 AAA domain TniB PF05621.11 CBZ23901.1 - 7.6e-07 28.7 0.0 0.0006 19.3 0.0 3.4 2 1 0 2 2 2 1 Bacterial TniB protein RuvB_N PF05496.12 CBZ23901.1 - 7e-06 25.9 1.8 0.26 11.0 0.0 4.1 3 1 0 3 3 3 2 Holliday junction DNA helicase RuvB P-loop domain AAA_7 PF12775.7 CBZ23901.1 - 9.1e-06 25.3 0.0 0.035 13.6 0.0 2.6 2 0 0 2 2 2 2 P-loop containing dynein motor region Zeta_toxin PF06414.12 CBZ23901.1 - 6.3e-05 22.3 2.7 0.07 12.4 0.0 4.5 5 0 0 5 5 4 1 Zeta toxin NACHT PF05729.12 CBZ23901.1 - 0.0001 22.3 0.1 0.14 12.1 0.0 3.8 4 0 0 4 4 3 1 NACHT domain Roc PF08477.13 CBZ23901.1 - 0.00034 20.8 0.0 1.1 9.6 0.0 2.9 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase TsaE PF02367.17 CBZ23901.1 - 0.00035 20.6 0.1 2.4 8.2 0.0 3.4 2 1 0 3 3 3 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_18 PF13238.6 CBZ23901.1 - 0.00037 21.1 0.4 0.57 10.7 0.0 3.7 2 1 1 3 3 3 1 AAA domain AAA_33 PF13671.6 CBZ23901.1 - 0.0004 20.6 1.0 0.35 11.0 0.0 3.9 4 0 0 4 4 4 1 AAA domain Mg_chelatase PF01078.21 CBZ23901.1 - 0.00086 18.7 0.1 2.8 7.3 0.1 3.5 2 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.22 CBZ23901.1 - 0.00096 19.5 0.2 1.6 9.2 0.0 3.3 4 0 0 4 4 2 1 RNA helicase TIP49 PF06068.13 CBZ23901.1 - 0.0012 18.1 0.1 0.32 10.1 0.0 3.1 2 1 1 3 3 3 1 TIP49 P-loop domain ATPase_2 PF01637.18 CBZ23901.1 - 0.0016 18.4 9.4 1.4 8.7 0.0 4.3 3 3 1 4 4 3 2 ATPase domain predominantly from Archaea AAA_25 PF13481.6 CBZ23901.1 - 0.0028 17.2 3.9 0.41 10.2 0.0 3.8 3 1 0 3 3 3 1 AAA domain DUF815 PF05673.13 CBZ23901.1 - 0.0034 16.6 0.1 0.8 8.8 0.1 3.0 2 1 0 2 2 2 1 Protein of unknown function (DUF815) DNA_pol3_delta2 PF13177.6 CBZ23901.1 - 0.0036 17.1 0.0 1.7 8.4 0.0 3.3 3 0 0 3 3 3 1 DNA polymerase III, delta subunit AAA_3 PF07726.11 CBZ23901.1 - 0.0038 17.1 0.1 1.6 8.6 0.0 3.5 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) RsgA_GTPase PF03193.16 CBZ23901.1 - 0.0039 17.1 0.2 6.6 6.6 0.0 3.5 3 1 0 3 3 3 0 RsgA GTPase ResIII PF04851.15 CBZ23901.1 - 0.005 16.9 0.0 0.31 11.0 0.0 3.3 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit Bac_DnaA PF00308.18 CBZ23901.1 - 0.0087 15.9 0.0 5.1 6.9 0.0 2.9 2 1 0 2 2 2 0 Bacterial dnaA protein AAA_29 PF13555.6 CBZ23901.1 - 0.012 15.3 0.0 8 6.3 0.0 2.7 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_30 PF13604.6 CBZ23901.1 - 0.012 15.3 0.0 7.9 6.1 0.0 3.0 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.15 CBZ23901.1 - 0.013 15.5 0.4 2.3 8.1 0.0 3.2 3 0 0 3 3 2 0 NTPase AAA_19 PF13245.6 CBZ23901.1 - 0.015 15.6 1.8 0.6 10.4 0.1 3.5 2 2 0 2 2 2 0 AAA domain ABC_tran PF00005.27 CBZ23901.1 - 0.02 15.4 1.8 13 6.2 0.0 3.9 4 1 0 4 4 3 0 ABC transporter AAA_23 PF13476.6 CBZ23901.1 - 0.03 14.8 19.0 2.3 8.6 0.0 4.3 2 1 1 3 3 2 0 AAA domain FACT-Spt16_Nlob PF14826.6 CBZ23901.1 - 0.039 13.8 2.8 28 4.5 0.0 3.5 3 1 0 3 3 3 0 FACT complex subunit SPT16 N-terminal lobe domain Tetrabrachion PF11401.8 CBZ23901.1 - 0.079 13.0 0.6 0.61 10.1 0.0 2.5 2 0 0 2 2 2 0 Tetrabrachion AAA_28 PF13521.6 CBZ23901.1 - 0.1 12.9 1.2 29 4.9 0.0 3.6 4 0 0 4 4 2 0 AAA domain DnaB_C PF03796.15 CBZ23901.1 - 0.16 11.3 3.8 0.51 9.6 0.0 3.0 3 0 0 3 3 2 0 DnaB-like helicase C terminal domain DASH_Spc19 PF08287.11 CBZ23901.1 - 0.16 11.8 12.9 0.82 9.5 12.6 2.4 1 1 0 1 1 1 0 Spc19 Spc7 PF08317.11 CBZ23901.1 - 0.29 10.0 13.4 0.68 8.8 13.4 1.6 1 0 0 1 1 1 0 Spc7 kinetochore protein UPF0242 PF06785.11 CBZ23901.1 - 5.4 7.1 12.5 1.3 9.0 7.8 1.9 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Lipase_3 PF01764.25 CBZ23902.1 - 2e-26 92.6 0.0 4e-19 68.9 0.0 2.3 2 0 0 2 2 2 2 Lipase (class 3) Abhydrolase_5 PF12695.7 CBZ23902.1 - 0.05 13.4 0.0 0.13 12.0 0.0 1.6 1 0 0 1 1 1 0 Alpha/beta hydrolase family DUF2974 PF11187.8 CBZ23902.1 - 0.11 12.0 0.0 4.6 6.7 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2974) HSP70 PF00012.20 CBZ23904.1 - 1.8e-25 89.2 3.7 1.4e-23 83.0 0.0 2.4 1 1 1 2 2 2 2 Hsp70 protein TPR_1 PF00515.28 CBZ23904.1 - 3.1e-10 39.4 0.3 2.4e-06 27.1 0.2 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.17 CBZ23904.1 - 1.2e-08 34.4 1.1 3.7e-05 23.5 0.3 3.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.6 CBZ23904.1 - 1.2e-07 31.3 0.6 0.00011 22.2 0.2 3.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.6 CBZ23904.1 - 2.6e-07 30.9 5.0 3e-05 24.2 0.1 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_9 PF13371.6 CBZ23904.1 - 2.7e-06 27.4 0.4 3.9e-05 23.7 0.0 2.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.6 CBZ23904.1 - 4.2e-06 26.4 0.4 0.16 12.0 0.2 3.4 3 0 0 3 3 2 2 Tetratricopeptide repeat TPR_19 PF14559.6 CBZ23904.1 - 2.9e-05 24.5 3.3 0.00013 22.4 1.3 2.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.6 CBZ23904.1 - 7.4e-05 23.3 0.6 0.00065 20.3 0.1 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.6 CBZ23904.1 - 0.00032 20.3 1.2 0.056 13.1 1.5 2.8 1 1 1 2 2 2 2 TPR repeat ANAPC3 PF12895.7 CBZ23904.1 - 0.0016 18.6 1.2 0.004 17.4 1.2 1.7 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 ANAPC5 PF12862.7 CBZ23904.1 - 0.0078 16.3 1.3 0.11 12.6 0.0 3.0 2 1 1 3 3 3 1 Anaphase-promoting complex subunit 5 TPR_10 PF13374.6 CBZ23904.1 - 0.011 15.6 0.4 0.11 12.4 0.4 2.9 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_6 PF13174.6 CBZ23904.1 - 0.017 15.8 1.9 0.34 11.7 1.2 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 CBZ23904.1 - 0.03 15.1 1.0 0.3 12.0 1.0 2.9 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_17 PF13431.6 CBZ23904.1 - 0.068 13.6 0.2 0.39 11.2 0.0 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat Sec16_C PF12931.7 CBZ23905.1 - 3.2e-14 53.3 0.0 5.1e-14 52.6 0.0 1.2 1 0 0 1 1 1 1 Sec23-binding domain of Sec16 GPHH PF16905.5 CBZ23905.1 - 0.061 13.1 2.1 0.44 10.3 0.1 3.0 3 0 0 3 3 3 0 Voltage-dependent L-type calcium channel, IQ-associated DUF572 PF04502.13 CBZ23906.1 - 2e-18 67.1 10.7 2.5e-17 63.5 10.7 2.0 1 1 0 1 1 1 1 Family of unknown function (DUF572) NAD_binding_9 PF13454.6 CBZ23907.1 - 0.048 13.6 0.1 0.091 12.8 0.1 1.4 1 0 0 1 1 1 0 FAD-NAD(P)-binding Dpy19 PF10034.9 CBZ23909.1 - 0.028 12.6 0.3 0.041 12.1 0.3 1.3 1 0 0 1 1 1 0 Q-cell neuroblast polarisation Thioredoxin_8 PF13905.6 CBZ23910.1 - 9.8e-06 25.8 0.0 0.42 11.0 0.0 3.2 3 0 0 3 3 3 2 Thioredoxin-like EF-hand_7 PF13499.6 CBZ23911.1 - 9.5e-08 32.4 0.0 9.8e-07 29.1 0.0 2.5 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_6 PF13405.6 CBZ23911.1 - 0.00057 19.6 0.1 0.0016 18.2 0.1 1.8 1 0 0 1 1 1 1 EF-hand domain EF-hand_1 PF00036.32 CBZ23911.1 - 0.00057 19.2 0.0 0.0012 18.2 0.0 1.6 1 0 0 1 1 1 1 EF hand EF-hand_8 PF13833.6 CBZ23911.1 - 0.0012 18.7 0.0 0.0088 15.9 0.0 2.2 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_5 PF13202.6 CBZ23911.1 - 0.057 12.9 0.2 0.19 11.3 0.0 2.0 2 0 0 2 2 2 0 EF hand Thioredoxin_8 PF13905.6 CBZ23912.1 - 8.8e-24 83.7 0.0 1.2e-23 83.2 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin-like AhpC-TSA PF00578.21 CBZ23912.1 - 1e-07 31.9 0.0 1.9e-07 31.0 0.0 1.4 1 1 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 CBZ23912.1 - 2.1e-07 30.8 0.0 2.7e-07 30.4 0.0 1.2 1 0 0 1 1 1 1 Redoxin Thioredoxin PF00085.20 CBZ23912.1 - 8.6e-07 28.9 0.1 5.8e-05 23.0 0.1 2.1 1 1 1 2 2 2 1 Thioredoxin Thioredoxin_2 PF13098.6 CBZ23912.1 - 5.8e-05 23.5 0.0 8.8e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin-like domain TraF PF13728.6 CBZ23912.1 - 0.00051 19.9 0.0 0.0043 16.9 0.0 1.9 2 0 0 2 2 2 1 F plasmid transfer operon protein Thioredoxin_7 PF13899.6 CBZ23912.1 - 0.0044 17.2 0.0 0.0082 16.3 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin-like DUF953 PF06110.11 CBZ23912.1 - 0.13 11.9 0.1 3 7.5 0.0 2.2 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF953) Thioredoxin_8 PF13905.6 CBZ23913.1 - 2.6e-22 78.9 0.0 3.4e-22 78.6 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin-like Redoxin PF08534.10 CBZ23913.1 - 5.6e-08 32.6 0.0 5.9e-08 32.6 0.0 1.2 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 CBZ23913.1 - 1.2e-07 31.7 0.0 1.5e-07 31.3 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin PF00085.20 CBZ23913.1 - 6.3e-06 26.1 0.1 4.3e-05 23.4 0.0 1.9 1 1 1 2 2 2 1 Thioredoxin TraF PF13728.6 CBZ23913.1 - 1e-05 25.5 0.0 3.7e-05 23.6 0.0 1.7 1 1 0 1 1 1 1 F plasmid transfer operon protein Thioredoxin_2 PF13098.6 CBZ23913.1 - 0.00075 19.9 0.0 0.0013 19.2 0.0 1.4 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_7 PF13899.6 CBZ23913.1 - 0.0028 17.8 0.0 0.0045 17.1 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin-like DUF953 PF06110.11 CBZ23913.1 - 0.02 14.5 0.0 6.5 6.4 0.0 2.2 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF953) Thioredoxin_8 PF13905.6 CBZ23914.1 - 2.2e-20 72.8 0.0 6.1e-16 58.5 0.0 2.3 2 0 0 2 2 2 2 Thioredoxin-like AhpC-TSA PF00578.21 CBZ23914.1 - 4.4e-12 46.0 0.0 7.1e-12 45.3 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 CBZ23914.1 - 5.9e-12 45.5 0.0 1.7e-11 44.0 0.0 1.7 2 0 0 2 2 2 1 Redoxin Thioredoxin PF00085.20 CBZ23914.1 - 2.7e-07 30.5 0.0 6.4e-07 29.3 0.0 1.7 2 0 0 2 2 2 1 Thioredoxin TraF PF13728.6 CBZ23914.1 - 1.3e-05 25.1 0.0 2.9e-05 24.0 0.0 1.6 2 0 0 2 2 2 1 F plasmid transfer operon protein Thioredoxin_7 PF13899.6 CBZ23914.1 - 0.00021 21.4 0.0 0.00048 20.3 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_2 PF13098.6 CBZ23914.1 - 0.00043 20.7 0.1 0.0024 18.3 0.0 2.0 2 0 0 2 2 2 1 Thioredoxin-like domain Thioredoxin_9 PF14595.6 CBZ23914.1 - 0.019 14.8 0.0 0.042 13.6 0.0 1.5 2 0 0 2 2 2 0 Thioredoxin DUF4234 PF14018.6 CBZ23914.1 - 0.048 13.8 0.1 0.075 13.2 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4234) Hex_IIIa PF02455.16 CBZ23914.1 - 0.21 10.3 0.0 0.27 9.9 0.0 1.1 1 0 0 1 1 1 0 Hexon-associated protein (IIIa) Thioredoxin_8 PF13905.6 CBZ23915.1 - 9.3e-11 41.9 0.0 1.8e-10 41.0 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin-like AhpC-TSA PF00578.21 CBZ23915.1 - 0.0019 18.1 0.0 0.0031 17.4 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 CBZ23915.1 - 0.035 13.8 0.0 0.058 13.1 0.0 1.3 1 0 0 1 1 1 0 Redoxin PSP1 PF04468.12 CBZ23916.1 - 3.6e-13 49.6 0.1 6.3e-13 48.8 0.1 1.4 1 0 0 1 1 1 1 PSP1 C-terminal conserved region Ank_2 PF12796.7 CBZ23918.1 - 2.9e-25 88.7 0.1 1.3e-08 35.3 0.0 4.0 2 1 2 4 4 4 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CBZ23918.1 - 3.4e-24 84.9 0.2 2.1e-10 40.9 0.0 4.5 3 1 1 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 CBZ23918.1 - 7.7e-20 68.9 0.1 0.023 15.2 0.0 6.6 6 0 0 6 6 6 5 Ankyrin repeat Ank PF00023.30 CBZ23918.1 - 1.4e-14 53.8 0.1 0.015 15.7 0.0 6.6 6 0 0 6 6 6 3 Ankyrin repeat Ank_5 PF13857.6 CBZ23918.1 - 2.2e-14 53.3 1.0 4.9e-06 26.7 0.0 5.9 3 2 3 6 6 6 4 Ankyrin repeats (many copies) Ribosomal_L4 PF00573.22 CBZ23919.1 - 2e-35 122.2 0.1 3.1e-35 121.6 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family Ribos_L4_asso_C PF14374.6 CBZ23919.1 - 6e-20 71.1 5.0 1.3e-19 70.0 3.0 2.3 2 0 0 2 2 2 1 60S ribosomal protein L4 C-terminal domain Ribosomal_L4 PF00573.22 CBZ23920.1 - 1.3e-35 122.9 0.1 2e-35 122.2 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family Ribos_L4_asso_C PF14374.6 CBZ23920.1 - 3.5e-20 71.8 4.9 1e-19 70.4 3.0 2.3 2 0 0 2 2 2 1 60S ribosomal protein L4 C-terminal domain Ku PF02735.16 CBZ23922.1 - 3.3e-23 82.5 0.0 7.2e-23 81.4 0.0 1.5 2 0 0 2 2 2 1 Ku70/Ku80 beta-barrel domain Ku_N PF03731.15 CBZ23922.1 - 2.1e-17 63.6 0.0 1.5e-10 41.2 0.0 2.7 3 0 0 3 3 3 2 Ku70/Ku80 N-terminal alpha/beta domain Ku_C PF03730.14 CBZ23922.1 - 2e-05 25.2 0.4 0.062 14.0 0.3 2.4 2 0 0 2 2 2 2 Ku70/Ku80 C-terminal arm cNMP_binding PF00027.29 CBZ23923.1 - 2.1e-16 59.8 0.0 1e-07 31.9 0.0 4.6 4 0 0 4 4 4 4 Cyclic nucleotide-binding domain Band_3_cyto PF07565.13 CBZ23924.1 - 0.64 9.8 9.0 0.85 9.4 9.0 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Nexin_C PF08628.12 CBZ23924.1 - 1.4 9.6 8.6 6.3 7.4 7.1 2.7 2 1 0 2 2 2 0 Sorting nexin C terminal TFB6 PF17110.5 CBZ23924.1 - 2.9 7.6 9.1 4.6 6.9 9.1 1.4 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH SseB PF07179.12 CBZ23925.1 - 0.00056 20.2 0.0 1.1 9.6 0.0 2.7 2 0 0 2 2 2 2 SseB protein N-terminal domain ADH_zinc_N_2 PF13602.6 CBZ23926.1 - 2e-15 58.0 0.0 5.8e-15 56.5 0.0 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 CBZ23926.1 - 1.9e-10 40.6 1.4 1.3e-09 37.9 0.0 2.5 2 1 1 3 3 3 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 CBZ23926.1 - 1.2e-08 35.0 0.0 3.1e-08 33.7 0.0 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Baculo_PEP_C PF04513.12 CBZ23927.1 - 9e-05 22.5 7.2 0.11 12.5 2.0 2.9 3 1 1 4 4 3 3 Baculovirus polyhedron envelope protein, PEP, C terminus DUF4795 PF16043.5 CBZ23927.1 - 0.0015 18.2 3.7 0.0015 18.2 3.7 3.4 3 0 0 3 3 3 1 Domain of unknown function (DUF4795) Spc7 PF08317.11 CBZ23927.1 - 0.0048 15.8 4.9 0.0048 15.8 4.9 3.2 3 1 0 3 3 3 1 Spc7 kinetochore protein COG5 PF10392.9 CBZ23927.1 - 0.019 15.2 0.3 0.019 15.2 0.3 3.2 3 0 0 3 3 3 0 Golgi transport complex subunit 5 BLOC1_2 PF10046.9 CBZ23927.1 - 0.032 14.5 9.7 2.3 8.6 1.0 3.9 3 1 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 AATF-Che1 PF13339.6 CBZ23927.1 - 0.072 13.8 12.8 2.1 9.0 1.4 3.8 3 1 1 4 4 4 0 Apoptosis antagonizing transcription factor LcrV PF04792.12 CBZ23927.1 - 0.077 12.3 0.1 0.13 11.5 0.1 1.3 1 0 0 1 1 1 0 V antigen (LcrV) protein Mto2_bdg PF12808.7 CBZ23927.1 - 0.082 13.2 0.4 0.082 13.2 0.4 4.0 4 1 1 5 5 3 0 Micro-tubular organiser Mto1 C-term Mto2-binding region YabA PF06156.13 CBZ23927.1 - 0.1 13.3 13.7 0.064 13.9 1.1 4.2 4 1 0 4 4 4 0 Initiation control protein YabA EzrA PF06160.12 CBZ23927.1 - 0.12 10.5 9.6 0.019 13.1 1.4 2.8 3 0 0 3 3 3 0 Septation ring formation regulator, EzrA TraF_2 PF13729.6 CBZ23927.1 - 0.16 11.3 2.0 0.43 9.9 0.6 2.1 2 0 0 2 2 2 0 F plasmid transfer operon, TraF, protein HALZ PF02183.18 CBZ23927.1 - 0.18 12.0 0.2 0.18 12.0 0.2 3.1 4 0 0 4 4 2 0 Homeobox associated leucine zipper AAA_23 PF13476.6 CBZ23927.1 - 0.33 11.4 8.6 7.5 7.0 0.2 3.2 3 0 0 3 3 3 0 AAA domain FlaC_arch PF05377.11 CBZ23927.1 - 0.38 11.2 1.8 88 3.6 0.4 3.8 2 2 0 2 2 2 0 Flagella accessory protein C (FlaC) Spc24 PF08286.11 CBZ23927.1 - 0.55 10.5 16.3 0.8 10.0 0.0 4.4 3 1 0 3 3 3 0 Spc24 subunit of Ndc80 KASH_CCD PF14662.6 CBZ23927.1 - 0.9 9.3 16.9 0.1 12.4 2.3 3.0 3 1 0 3 3 2 0 Coiled-coil region of CCDC155 or KASH Jnk-SapK_ap_N PF09744.9 CBZ23927.1 - 0.95 9.7 20.4 0.22 11.7 2.8 3.4 3 1 0 3 3 3 0 JNK_SAPK-associated protein-1 NPV_P10 PF05531.12 CBZ23927.1 - 1.3 9.5 6.8 4.8 7.7 0.7 3.7 3 1 1 4 4 4 0 Nucleopolyhedrovirus P10 protein Fib_alpha PF08702.10 CBZ23927.1 - 1.8 8.7 14.9 0.43 10.8 0.7 4.2 3 2 1 5 5 5 0 Fibrinogen alpha/beta chain family SKA1 PF07160.12 CBZ23927.1 - 3.9 7.2 11.7 1.8 8.3 2.3 3.3 3 1 0 3 3 3 0 Spindle and kinetochore-associated protein 1 DUF501 PF04417.12 CBZ23927.1 - 4.3 7.1 9.4 2 8.2 2.3 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF501) FapA PF03961.13 CBZ23927.1 - 4.4 5.8 9.8 0.58 8.7 1.3 2.8 3 0 0 3 3 3 0 Flagellar Assembly Protein A Cnn_1N PF07989.11 CBZ23927.1 - 4.8 7.4 13.7 3.3 7.9 0.5 3.8 3 1 1 4 4 4 0 Centrosomin N-terminal motif 1 ZapB PF06005.12 CBZ23927.1 - 4.9 7.7 25.9 6.9 7.2 5.2 4.6 3 1 0 3 3 3 0 Cell division protein ZapB HMMR_N PF15905.5 CBZ23927.1 - 5.4 6.4 20.2 1.3 8.5 0.1 3.6 3 1 0 3 3 3 0 Hyaluronan mediated motility receptor N-terminal TMF_TATA_bd PF12325.8 CBZ23927.1 - 5.6 7.2 20.3 0.18 12.1 0.7 4.2 3 2 0 3 3 3 0 TATA element modulatory factor 1 TATA binding MMR1 PF08505.10 CBZ23927.1 - 6.3 7.0 12.9 0.79 10.0 0.2 3.0 3 0 0 3 3 3 0 Mitochondrial Myo2 receptor-related protein Seryl_tRNA_N PF02403.22 CBZ23927.1 - 7.5 6.8 19.5 0.16 12.2 1.8 4.5 3 2 1 5 5 5 0 Seryl-tRNA synthetase N-terminal domain AA_synth PF06684.11 CBZ23928.1 - 0.0034 16.9 0.1 0.018 14.6 0.0 2.1 2 0 0 2 2 2 1 Amino acid synthesis Kinesin PF00225.23 CBZ23930.1 - 5.1e-83 278.8 0.0 6e-82 275.2 0.0 2.8 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 CBZ23930.1 - 3.3e-15 56.3 0.0 2.1e-14 53.7 0.0 2.5 2 0 0 2 2 2 1 Microtubule binding DUF2938 PF11158.8 CBZ23932.1 - 0.13 11.7 0.0 0.22 11.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2938) FGE-sulfatase PF03781.16 CBZ23933.1 - 3.2e-22 79.3 0.9 7e-22 78.2 0.9 1.6 1 0 0 1 1 1 1 Sulfatase-modifying factor enzyme 1 Methyltransf_25 PF13649.6 CBZ23933.1 - 3.7e-06 27.5 0.2 0.0011 19.6 0.2 2.7 1 1 0 1 1 1 1 Methyltransferase domain DinB_2 PF12867.7 CBZ23933.1 - 3.9e-05 24.2 0.0 8.9e-05 23.0 0.0 1.7 1 0 0 1 1 1 1 DinB superfamily Methyltransf_31 PF13847.6 CBZ23933.1 - 5.8e-05 22.9 0.0 0.016 15.0 0.0 2.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 CBZ23933.1 - 0.00078 19.3 0.0 0.002 18.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CBZ23933.1 - 0.011 16.4 0.1 0.092 13.4 0.1 2.3 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.12 CBZ23933.1 - 0.047 14.4 0.0 0.93 10.3 0.0 2.5 1 1 0 1 1 1 0 Methyltransferase domain ABC2_membrane PF01061.24 CBZ23935.1 - 2.2e-05 24.0 18.2 4.3e-05 23.0 18.2 1.4 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.27 CBZ23935.1 - 0.009 16.5 0.0 0.014 15.9 0.0 1.2 1 0 0 1 1 1 1 ABC transporter LETM1 PF07766.13 CBZ23936.1 - 5.1e-62 209.6 0.0 2.4e-61 207.4 0.0 1.9 2 1 0 2 2 2 1 LETM1-like protein DASH_Duo1 PF08651.10 CBZ23936.1 - 0.06 13.1 0.1 0.14 11.9 0.1 1.5 1 0 0 1 1 1 0 DASH complex subunit Duo1 Peptidase_A22B PF04258.13 CBZ23937.1 - 2.8e-62 210.8 18.6 7.9e-57 192.9 9.9 2.0 1 1 1 2 2 2 2 Signal peptide peptidase SPP PF06550.11 CBZ23937.1 - 0.048 13.1 13.6 0.22 11.0 13.6 2.0 1 1 0 1 1 1 0 Signal-peptide peptidase, presenilin aspartyl protease DUF5477 PF17571.2 CBZ23937.1 - 0.091 12.9 0.2 0.2 11.8 0.2 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5477) IPPT PF01715.17 CBZ23938.1 - 1e-14 54.9 0.0 1.5e-14 54.4 0.0 1.2 1 0 0 1 1 1 1 IPP transferase zf-met PF12874.7 CBZ23938.1 - 5.1e-05 23.5 0.5 8.9e-05 22.7 0.5 1.4 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 CBZ23938.1 - 0.058 13.7 0.2 0.11 12.8 0.2 1.5 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding DUF3449 PF11931.8 CBZ23938.1 - 0.12 12.1 0.3 0.22 11.3 0.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3449) SLC35F PF06027.12 CBZ23939.1 - 4.6e-61 206.9 26.3 9.5e-48 163.2 5.8 2.0 2 0 0 2 2 2 2 Solute carrier family 35 CRT-like PF08627.10 CBZ23939.1 - 5e-13 48.7 5.7 5e-13 48.7 5.7 1.7 2 0 0 2 2 2 1 CRT-like, chloroquine-resistance transporter-like EamA PF00892.20 CBZ23939.1 - 1.8e-07 31.4 41.5 0.00065 19.9 14.5 3.0 3 0 0 3 3 3 2 EamA-like transporter family PhyH PF05721.13 CBZ23940.1 - 4.6e-05 23.8 0.0 0.00012 22.5 0.0 1.7 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) C1_1 PF00130.22 CBZ23940.1 - 0.00025 20.9 4.1 0.00025 20.9 4.1 2.1 2 1 0 2 2 2 1 Phorbol esters/diacylglycerol binding domain (C1 domain) PHD PF00628.29 CBZ23940.1 - 0.015 15.1 9.1 0.04 13.8 9.1 1.8 1 1 0 1 1 1 0 PHD-finger Prok-RING_1 PF14446.6 CBZ23940.1 - 0.16 11.9 9.2 0.41 10.6 9.2 1.7 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 PHD_4 PF16866.5 CBZ23940.1 - 0.62 10.2 7.8 1.4 9.0 7.8 1.6 1 0 0 1 1 1 0 PHD-finger Arf PF00025.21 CBZ23941.1 - 9.2e-64 214.1 0.0 1e-63 213.9 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 CBZ23941.1 - 7.2e-15 54.9 0.0 8.7e-15 54.6 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Roc PF08477.13 CBZ23941.1 - 1e-14 54.8 0.0 1.4e-14 54.4 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 CBZ23941.1 - 2e-14 53.5 0.0 2.3e-14 53.3 0.0 1.0 1 0 0 1 1 1 1 Ras family G-alpha PF00503.20 CBZ23941.1 - 3.3e-12 46.2 0.2 2.1e-09 37.0 0.0 2.4 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.12 CBZ23941.1 - 6.7e-11 42.0 0.0 7.8e-11 41.8 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 CBZ23941.1 - 3e-08 33.7 0.0 4.2e-08 33.3 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase TniB PF05621.11 CBZ23941.1 - 0.0021 17.5 0.0 0.0037 16.7 0.0 1.4 1 0 0 1 1 1 1 Bacterial TniB protein cobW PF02492.19 CBZ23941.1 - 0.0052 16.4 0.0 0.07 12.7 0.0 2.0 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_16 PF13191.6 CBZ23941.1 - 0.047 14.1 0.5 0.25 11.7 0.5 1.9 1 1 0 1 1 1 0 AAA ATPase domain RsgA_GTPase PF03193.16 CBZ23941.1 - 0.058 13.3 0.0 11 5.9 0.0 2.2 2 0 0 2 2 2 0 RsgA GTPase DUF4202 PF13875.6 CBZ23942.1 - 0.0045 16.9 0.4 0.013 15.5 0.1 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4202) DUF4932 PF16286.5 CBZ23942.1 - 0.016 14.5 0.0 0.025 13.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4932) PrgH PF09480.10 CBZ23942.1 - 0.071 12.4 0.2 0.14 11.5 0.2 1.4 1 0 0 1 1 1 0 Type III secretion system protein PrgH-EprH (PrgH) Cyt-b5 PF00173.28 CBZ23943.1 - 1.4e-08 34.8 0.0 2.2e-08 34.1 0.0 1.3 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Amidohydro_1 PF01979.20 CBZ23944.1 - 5.5e-54 183.8 0.0 8.3e-54 183.2 0.0 1.3 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 CBZ23944.1 - 1.3e-05 24.8 0.0 0.05 13.1 0.0 2.5 2 1 0 2 2 2 2 Amidohydrolase family RRM_1 PF00076.22 CBZ23945.1 - 4.9e-07 29.5 0.0 7.8e-07 28.8 0.0 1.4 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 CBZ23945.1 - 0.014 15.0 0.0 0.016 14.8 0.0 1.1 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 CBZ23945.1 - 0.077 12.9 0.0 0.11 12.3 0.0 1.2 1 0 0 1 1 1 0 Occluded RNA-recognition motif HMG_box PF00505.19 CBZ23947.1 - 5.6e-34 116.4 11.0 3.1e-21 75.5 1.4 2.8 2 0 0 2 2 2 2 HMG (high mobility group) box HMG_box_2 PF09011.10 CBZ23947.1 - 8.7e-21 74.3 18.3 4.3e-12 46.4 0.9 2.9 3 0 0 3 3 3 2 HMG-box domain Protamine_like PF06382.11 CBZ23947.1 - 8.1e-09 35.8 11.6 6.4e-06 26.4 3.5 2.2 1 1 1 2 2 2 2 Protamine and protamine like DEK_C PF08766.11 CBZ23947.1 - 1.8e-06 27.7 0.0 3.9e-06 26.7 0.0 1.5 1 0 0 1 1 1 1 DEK C terminal domain HMG_box_5 PF14887.6 CBZ23947.1 - 1.8e-05 24.6 14.3 0.00043 20.2 0.6 2.8 3 0 0 3 3 3 2 HMG (high mobility group) box 5 DUF736 PF05284.12 CBZ23947.1 - 0.0086 16.0 0.3 6.2 6.8 0.1 2.7 3 0 0 3 3 3 2 Protein of unknown function (DUF736) COX4 PF02936.14 CBZ23947.1 - 0.02 14.9 3.9 2 8.5 0.1 2.5 2 0 0 2 2 2 0 Cytochrome c oxidase subunit IV DUF1088 PF06469.11 CBZ23947.1 - 0.15 11.7 1.7 0.38 10.4 0.6 2.0 1 1 1 2 2 2 0 Domain of Unknown Function (DUF1088) YABBY PF04690.13 CBZ23947.1 - 0.21 12.1 5.8 0.048 14.2 1.9 1.9 1 1 1 2 2 2 0 YABBY protein DUF2582 PF10771.9 CBZ23947.1 - 0.58 10.4 3.2 6.4 7.0 0.1 2.8 3 0 0 3 3 3 0 Winged helix-turn-helix domain (DUF2582) PTP_tm PF18861.1 CBZ23948.1 - 0.19 11.7 1.7 2 8.3 0.2 2.2 2 0 0 2 2 2 0 Transmembrane domain of protein tyrosine phosphatase, receptor type J DUF1634 PF07843.11 CBZ23948.1 - 0.35 11.0 6.0 5.7 7.1 0.2 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF1634) Nop14 PF04147.12 CBZ23949.1 - 2.1 6.5 6.8 2.6 6.2 6.8 1.0 1 0 0 1 1 1 0 Nop14-like family Peptidase_C1 PF00112.23 CBZ23950.1 - 6.1e-61 206.3 5.4 7.4e-61 206.0 5.4 1.1 1 0 0 1 1 1 1 Papain family cysteine protease Peptidase_C1_2 PF03051.15 CBZ23950.1 - 8.8e-06 24.8 1.3 0.0012 17.7 0.5 2.1 2 0 0 2 2 2 2 Peptidase C1-like family Propeptide_C1 PF08127.13 CBZ23950.1 - 0.013 15.4 0.0 0.028 14.3 0.0 1.6 1 0 0 1 1 1 0 Peptidase family C1 propeptide CAMSAP_CKK PF08683.11 CBZ23950.1 - 0.095 12.8 0.1 0.19 11.9 0.1 1.4 1 0 0 1 1 1 0 Microtubule-binding calmodulin-regulated spectrin-associated DUF4203 PF13886.6 CBZ23951.1 - 0.06 13.0 0.1 0.06 13.0 0.1 1.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4203) Phage_F PF02305.17 CBZ23953.1 - 0.018 13.8 0.0 0.041 12.6 0.0 1.5 2 0 0 2 2 2 0 Capsid protein (F protein) Topoisom_I PF01028.20 CBZ23953.1 - 0.16 11.2 0.1 0.22 10.7 0.1 1.2 1 0 0 1 1 1 0 Eukaryotic DNA topoisomerase I, catalytic core U-box PF04564.15 CBZ23955.1 - 3.6e-12 46.3 0.0 3e-11 43.3 0.0 2.5 3 0 0 3 3 3 1 U-box domain zf-Nse PF11789.8 CBZ23955.1 - 0.00013 21.7 0.0 0.00036 20.3 0.0 1.7 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit VESA1_N PF12785.7 CBZ23955.1 - 0.055 12.4 0.1 5 6.0 0.0 2.1 2 0 0 2 2 2 0 Variant erythrocyte surface antigen-1 zf-NOSIP PF15906.5 CBZ23955.1 - 0.14 12.3 0.0 0.32 11.2 0.0 1.5 1 0 0 1 1 1 0 Zinc-finger of nitric oxide synthase-interacting protein DUF3338 PF11819.8 CBZ23956.1 - 0.01 15.8 0.6 0.17 11.9 0.1 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF3338) HSP90 PF00183.18 CBZ23957.1 - 1.3e-171 572.0 6.5 1.6e-171 571.7 6.5 1.0 1 0 0 1 1 1 1 Hsp90 protein HATPase_c_3 PF13589.6 CBZ23957.1 - 6.4e-08 32.5 0.0 1.7e-07 31.1 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 CBZ23957.1 - 2.2e-06 28.2 0.0 8.9e-06 26.2 0.0 2.1 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase GSH-S_ATP PF02955.16 CBZ23957.1 - 0.12 11.7 0.1 1.3 8.4 0.0 2.3 2 0 0 2 2 2 0 Prokaryotic glutathione synthetase, ATP-grasp domain Mpp10 PF04006.12 CBZ23958.1 - 7.8e-63 212.9 42.9 2.1e-62 211.5 42.9 2.0 1 1 0 1 1 1 1 Mpp10 protein WD40 PF00400.32 CBZ23959.1 - 1.3e-19 70.2 8.8 0.00023 21.9 0.0 5.9 6 0 0 6 6 6 5 WD domain, G-beta repeat EF_TS PF00889.19 CBZ23961.1 - 4.7e-14 52.5 0.0 1.3e-13 51.0 0.0 1.6 1 1 1 2 2 2 1 Elongation factor TS HOIP-UBA PF16678.5 CBZ23961.1 - 0.12 12.4 0.2 2.1 8.3 0.0 2.7 3 1 1 4 4 4 0 HOIP UBA domain pair FG-GAP PF01839.23 CBZ23962.1 - 0.0055 16.8 2.9 0.016 15.4 2.9 1.7 1 0 0 1 1 1 1 FG-GAP repeat BBS2_Mid PF14783.6 CBZ23962.1 - 0.0083 16.2 0.1 0.22 11.6 0.1 2.5 1 1 1 2 2 2 2 Ciliary BBSome complex subunit 2, middle region VCBS PF13517.6 CBZ23962.1 - 0.046 14.3 0.1 0.15 12.7 0.1 1.9 1 0 0 1 1 1 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella Itfg2 PF15907.5 CBZ23962.1 - 0.17 10.9 0.0 0.6 9.1 0.0 1.8 2 0 0 2 2 2 0 Integrin-alpha FG-GAP repeat-containing protein 2 CLAMP PF14769.6 CBZ23963.1 - 0.0042 17.5 0.0 0.36 11.3 0.0 2.4 2 0 0 2 2 2 2 Flagellar C1a complex subunit C1a-32 RRM_1 PF00076.22 CBZ23965.1 - 1.3e-21 76.2 0.0 1.5e-12 47.2 0.0 3.5 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Radial_spoke PF04712.12 CBZ23967.1 - 5.1e-125 418.2 0.0 6.4e-125 417.9 0.0 1.0 1 0 0 1 1 1 1 Radial spokehead-like protein Med3 PF11593.8 CBZ23967.1 - 0.45 9.7 2.4 0.71 9.0 2.4 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal PIR PF00399.19 CBZ23967.1 - 5.6 6.7 5.9 4.2 7.1 0.4 2.6 2 0 0 2 2 2 0 Yeast PIR protein repeat PHO4 PF01384.20 CBZ23968.1 - 7.8e-20 71.2 0.0 8.7e-20 71.0 0.0 1.0 1 0 0 1 1 1 1 Phosphate transporter family DcpS_C PF11969.8 CBZ23969.1 - 8.1e-23 81.1 0.7 1.7e-22 80.1 0.7 1.5 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding HIT PF01230.23 CBZ23969.1 - 6.5e-13 49.2 0.6 1.9e-12 47.8 0.4 1.8 2 0 0 2 2 2 1 HIT domain zf-C2HE PF16278.5 CBZ23969.1 - 1.9e-09 37.8 0.0 3.8e-09 36.9 0.0 1.5 1 0 0 1 1 1 1 C2HE / C2H2 / C2HC zinc-binding finger zf-C2H2_2 PF12756.7 CBZ23969.1 - 0.073 13.4 0.2 0.16 12.4 0.2 1.6 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) DUF2207 PF09972.9 CBZ23970.1 - 0.003 16.4 0.1 0.0031 16.3 0.1 1.0 1 0 0 1 1 1 1 Predicted membrane protein (DUF2207) YukC PF10140.9 CBZ23970.1 - 0.026 13.4 0.1 0.034 13.0 0.1 1.2 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukC PET117 PF15786.5 CBZ23970.1 - 0.033 14.5 0.2 0.056 13.7 0.2 1.4 1 0 0 1 1 1 0 PET assembly of cytochrome c oxidase, mitochondrial DUF919 PF06034.11 CBZ23970.1 - 0.069 13.0 0.4 0.11 12.3 0.4 1.5 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF919) ABC2_membrane_3 PF12698.7 CBZ23971.1 - 2.4e-61 207.8 53.8 1.7e-43 149.1 21.9 3.3 3 0 0 3 3 3 2 ABC-2 family transporter protein ABC_tran PF00005.27 CBZ23971.1 - 2e-54 183.8 0.0 9.4e-27 94.2 0.0 2.5 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 CBZ23971.1 - 3.8e-12 46.6 4.5 0.00041 20.3 0.0 4.5 3 1 1 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 CBZ23971.1 - 4.1e-10 39.5 0.0 2.7e-05 23.7 0.2 3.1 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 CBZ23971.1 - 6.7e-05 22.6 1.5 0.007 16.1 0.2 2.8 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_30 PF13604.6 CBZ23971.1 - 0.00048 19.9 1.2 0.099 12.3 0.1 2.5 2 0 0 2 2 2 2 AAA domain AAA_23 PF13476.6 CBZ23971.1 - 0.00082 19.9 0.6 0.22 12.0 0.1 2.2 2 0 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 CBZ23971.1 - 0.0059 16.5 0.7 0.89 9.4 0.1 2.5 2 0 0 2 2 2 1 RsgA GTPase AAA_25 PF13481.6 CBZ23971.1 - 0.0085 15.7 0.8 1.9 8.0 0.0 2.6 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 CBZ23971.1 - 0.083 13.3 0.0 6.2 7.3 0.0 2.7 2 0 0 2 2 2 0 RNA helicase AAA_27 PF13514.6 CBZ23971.1 - 0.13 11.8 0.5 1.1 8.8 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 CBZ23971.1 - 0.69 10.3 2.4 4.5 7.7 0.1 2.9 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) SRP54 PF00448.22 CBZ23971.1 - 0.9 9.1 4.6 1.3 8.6 0.5 2.2 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain zf-CCHC_2 PF13696.6 CBZ23972.1 - 1.2e-09 37.8 3.5 2.1e-09 37.0 3.5 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-C2H2_jaz PF12171.8 CBZ23972.1 - 6.3e-05 23.1 0.2 0.00033 20.8 0.5 2.0 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding eIF3g PF12353.8 CBZ23972.1 - 0.0036 17.7 0.0 0.013 15.9 0.0 1.9 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit G zf-CCHC_5 PF14787.6 CBZ23972.1 - 0.015 15.0 1.3 0.015 15.0 1.3 2.1 2 0 0 2 2 2 0 GAG-polyprotein viral zinc-finger zf-C2H2 PF00096.26 CBZ23972.1 - 0.031 14.7 0.1 0.031 14.7 0.1 3.2 3 0 0 3 3 3 0 Zinc finger, C2H2 type zf-LITAF-like PF10601.9 CBZ23972.1 - 0.04 14.2 0.4 0.04 14.2 0.4 1.6 2 0 0 2 2 2 0 LITAF-like zinc ribbon domain zf-C2H2_4 PF13894.6 CBZ23972.1 - 0.093 13.6 0.2 0.093 13.6 0.2 3.3 4 0 0 4 4 4 0 C2H2-type zinc finger zf-met PF12874.7 CBZ23972.1 - 0.18 12.2 0.3 0.49 10.9 0.3 1.8 1 0 0 1 1 1 0 Zinc-finger of C2H2 type zf-NF-X1 PF01422.17 CBZ23973.1 - 9.1e-07 28.8 37.4 3.8e-05 23.6 14.0 14.8 15 0 0 15 15 15 6 NF-X1 type zinc finger ERCC3_RAD25_C PF16203.5 CBZ23974.1 - 9.5e-62 208.4 0.0 3.5e-54 183.6 0.0 2.3 2 0 0 2 2 2 2 ERCC3/RAD25/XPB C-terminal helicase ResIII PF04851.15 CBZ23974.1 - 6.8e-14 52.2 0.0 1.1e-13 51.6 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 CBZ23974.1 - 1.1e-09 38.7 0.0 2.6e-09 37.4 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Helicase_C_3 PF13625.6 CBZ23974.1 - 4.5e-08 33.3 0.3 1.5e-07 31.6 0.3 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 CBZ23974.1 - 0.0081 15.9 0.1 0.015 15.1 0.1 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Ank_2 PF12796.7 CBZ23976.1 - 3e-09 37.3 0.3 0.00072 20.1 0.0 2.6 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CBZ23976.1 - 5.7e-09 36.3 0.5 0.00074 20.0 0.0 3.2 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 CBZ23976.1 - 1.2e-05 25.5 1.1 0.17 12.4 0.1 4.0 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.6 CBZ23976.1 - 0.00013 22.2 0.7 2.5 8.9 0.0 4.0 3 0 0 3 3 3 1 Ankyrin repeat Ank_5 PF13857.6 CBZ23976.1 - 0.0002 21.6 1.2 0.38 11.1 0.2 3.4 2 1 0 2 2 2 2 Ankyrin repeats (many copies) RNase_T PF00929.24 CBZ23977.1 - 4.5e-25 89.1 0.0 7.2e-25 88.4 0.0 1.3 1 0 0 1 1 1 1 Exonuclease DUF5051 PF16473.5 CBZ23977.1 - 0.023 14.7 0.0 0.04 13.9 0.0 1.5 1 0 0 1 1 1 0 3' exoribonuclease, RNase T-like RNase_T PF00929.24 CBZ23979.1 - 1.9e-26 93.6 0.0 2.6e-26 93.1 0.0 1.2 1 0 0 1 1 1 1 Exonuclease DUF5051 PF16473.5 CBZ23979.1 - 0.089 12.8 0.0 0.14 12.2 0.0 1.3 1 0 0 1 1 1 0 3' exoribonuclease, RNase T-like RNase_T PF00929.24 CBZ23980.1 - 9e-27 94.6 0.0 3.4e-25 89.5 0.0 2.2 1 1 0 1 1 1 1 Exonuclease Peptidase_S64 PF08192.11 CBZ23981.1 - 2 6.8 3.4 4.1 5.8 3.4 1.4 1 0 0 1 1 1 0 Peptidase family S64 Cofilin_ADF PF00241.20 CBZ23983.1 - 2.8e-30 104.6 0.1 3.1e-30 104.5 0.1 1.0 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein CaATP_NAI PF12515.8 CBZ23984.1 - 6.4e-16 57.7 0.3 6.4e-16 57.7 0.3 2.0 2 0 0 2 2 2 1 Ca2+-ATPase N terminal autoinhibitory domain OrsD PF12013.8 CBZ23984.1 - 0.096 13.1 3.8 0.23 11.9 0.5 2.7 2 0 0 2 2 2 0 Orsellinic acid/F9775 biosynthesis cluster protein D Gly-zipper_Omp PF13488.6 CBZ23987.1 - 0.009 16.0 8.9 0.009 16.0 8.9 1.8 2 0 0 2 2 2 1 Glycine zipper Gly-zipper_OmpA PF13436.6 CBZ23987.1 - 0.079 12.8 12.1 0.23 11.2 12.1 1.8 1 0 0 1 1 1 0 Glycine-zipper domain Rick_17kDa_Anti PF05433.15 CBZ23987.1 - 6.6 6.7 17.2 5.3 7.0 14.9 2.1 2 1 0 2 2 2 0 Glycine zipper 2TM domain Rad51 PF08423.11 CBZ23989.1 - 1.8e-21 76.5 0.3 5.2e-11 42.3 0.0 2.3 2 0 0 2 2 2 2 Rad51 RecA PF00154.21 CBZ23989.1 - 3.8e-08 33.1 2.1 5e-07 29.5 0.1 2.1 2 0 0 2 2 2 1 recA bacterial DNA recombination protein ATPase PF06745.13 CBZ23989.1 - 3.2e-07 29.9 0.0 4.9e-07 29.3 0.0 1.3 1 0 0 1 1 1 1 KaiC DUF2075 PF09848.9 CBZ23989.1 - 0.016 14.5 0.0 0.028 13.7 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Metallophos PF00149.28 CBZ23990.1 - 1.1e-06 29.3 0.0 1.5e-06 28.9 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 CBZ23990.1 - 0.11 12.7 0.0 0.38 10.9 0.0 1.8 1 1 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain Metallophos_3 PF14582.6 CBZ23990.1 - 0.12 11.6 0.0 0.22 10.8 0.0 1.4 1 0 0 1 1 1 0 Metallophosphoesterase, calcineurin superfamily PPR_3 PF13812.6 CBZ23991.1 - 0.0036 17.3 0.0 0.014 15.4 0.0 2.0 2 0 0 2 2 2 1 Pentatricopeptide repeat domain PPR_1 PF12854.7 CBZ23991.1 - 0.027 14.2 0.0 0.064 13.0 0.0 1.6 1 0 0 1 1 1 0 PPR repeat PPR_2 PF13041.6 CBZ23991.1 - 0.031 14.5 0.0 0.16 12.2 0.0 2.2 2 0 0 2 2 2 0 PPR repeat family PPR PF01535.20 CBZ23991.1 - 0.1 12.9 0.0 12 6.4 0.0 3.3 3 0 0 3 3 3 0 PPR repeat HycH PF07450.11 CBZ23991.1 - 0.13 12.6 0.0 3.3 8.1 0.0 2.7 3 0 0 3 3 3 0 Formate hydrogenlyase maturation protein HycH zf-CCCH PF00642.24 CBZ23992.1 - 0.0075 16.2 0.4 0.012 15.5 0.4 1.3 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Torus PF16131.5 CBZ23992.1 - 0.017 15.8 0.0 0.035 14.8 0.0 1.4 1 0 0 1 1 1 0 Torus domain zf_CCCH_4 PF18345.1 CBZ23992.1 - 1 9.5 5.7 1.6 8.9 5.7 1.4 1 0 0 1 1 1 0 Zinc finger domain RNA_pol_Rpb4 PF03874.16 CBZ23994.1 - 4.8e-05 23.7 0.0 0.00011 22.5 0.0 1.5 2 0 0 2 2 2 1 RNA polymerase Rpb4 Prolamin_like PF05617.11 CBZ23994.1 - 0.042 14.0 0.0 0.063 13.5 0.0 1.3 1 0 0 1 1 1 0 Prolamin-like RRM_1 PF00076.22 CBZ23995.1 - 1.9e-15 56.4 0.1 2.2e-07 30.6 0.1 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 CBZ23995.1 - 0.079 13.0 0.2 3.4 7.7 0.0 2.4 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif C2-C2_1 PF11618.8 CBZ23996.1 - 2.8e-06 27.5 0.0 2.8e-06 27.5 0.0 3.6 4 1 1 5 5 5 1 First C2 domain of RPGR-interacting protein 1 Cep57_CLD PF14073.6 CBZ23996.1 - 0.0035 17.4 1.9 0.0035 17.4 1.9 5.1 3 1 2 5 5 5 1 Centrosome localisation domain of Cep57 DHR10 PF18595.1 CBZ23996.1 - 0.0044 17.1 15.1 0.0044 17.1 15.1 6.4 3 1 2 6 6 6 1 Designed helical repeat protein 10 domain Fez1 PF06818.15 CBZ23996.1 - 0.02 15.4 41.5 0.24 11.8 15.5 4.4 4 0 0 4 4 4 0 Fez1 Pkinase PF00069.25 CBZ23997.1 - 1.4e-41 142.6 0.0 1.6e-19 70.3 0.0 3.2 3 0 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ23997.1 - 6.8e-22 78.0 0.1 6.7e-13 48.5 0.0 2.7 3 0 0 3 3 3 2 Protein tyrosine kinase Kinase-like PF14531.6 CBZ23997.1 - 0.00032 20.1 0.0 0.63 9.3 0.0 2.5 2 0 0 2 2 2 2 Kinase-like APH PF01636.23 CBZ23997.1 - 0.013 15.4 0.5 0.077 12.9 0.2 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.11 CBZ23997.1 - 0.033 13.1 0.0 0.05 12.6 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Kdo PF06293.14 CBZ23997.1 - 0.2 11.0 0.0 0.38 10.1 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 CBZ23997.1 - 0.24 11.0 0.0 0.72 9.4 0.0 1.7 1 0 0 1 1 1 0 RIO1 family zf-met PF12874.7 CBZ23998.1 - 0.0044 17.4 0.4 0.0085 16.5 0.4 1.5 1 0 0 1 1 1 1 Zinc-finger of C2H2 type AKAP95 PF04988.12 CBZ23998.1 - 0.038 14.2 0.1 0.061 13.5 0.1 1.2 1 0 0 1 1 1 0 A-kinase anchoring protein 95 (AKAP95) UBA_4 PF14555.6 CBZ24000.1 - 1.8e-06 27.7 0.1 3.8e-06 26.6 0.1 1.5 1 0 0 1 1 1 1 UBA-like domain Thioredoxin_7 PF13899.6 CBZ24000.1 - 0.00047 20.3 0.2 0.0016 18.6 0.0 2.0 2 0 0 2 2 2 1 Thioredoxin-like ArfGap PF01412.18 CBZ24001.1 - 1.4e-38 131.6 0.1 1.4e-38 131.6 0.1 1.6 2 0 0 2 2 2 1 Putative GTPase activating protein for Arf FGF-BP1 PF06473.12 CBZ24001.1 - 0.74 9.6 10.0 1.2 8.9 10.0 1.2 1 0 0 1 1 1 0 FGF binding protein 1 (FGF-BP1) RPN2_C PF18004.1 CBZ24001.1 - 2.4 8.1 6.2 4.1 7.3 6.2 1.3 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain STI1 PF17830.1 CBZ24002.1 - 1.8e-12 47.0 12.6 1.8e-12 47.0 12.6 1.8 2 0 0 2 2 2 1 STI1 domain TPR_9 PF13371.6 CBZ24002.1 - 1.1e-05 25.4 0.5 1.1e-05 25.4 0.5 2.0 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_17 PF13431.6 CBZ24002.1 - 3.2e-05 24.0 0.3 0.36 11.3 0.0 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.6 CBZ24002.1 - 4.6e-05 23.0 0.2 0.1 12.3 0.0 3.1 2 1 1 3 3 3 2 TPR repeat TPR_1 PF00515.28 CBZ24002.1 - 7.9e-05 22.3 0.9 0.032 14.1 0.6 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.17 CBZ24002.1 - 0.00012 21.9 13.4 0.31 11.3 0.9 4.0 4 0 0 4 4 4 3 Tetratricopeptide repeat DUF2999 PF11212.8 CBZ24002.1 - 0.016 15.4 3.3 3.4 8.0 3.2 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF2999) Rrn6 PF10214.9 CBZ24002.1 - 0.028 13.0 0.7 0.033 12.7 0.7 1.0 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor EMC3_TMCO1 PF01956.16 CBZ24002.1 - 2.5 7.8 4.4 0.85 9.3 1.8 1.5 2 0 0 2 2 2 0 Integral membrane protein EMC3/TMCO1-like TPR_8 PF13181.6 CBZ24002.1 - 4.2 7.8 5.1 22 5.6 0.0 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat FHA PF00498.26 CBZ24003.1 - 1e-07 32.2 0.0 1.4e-06 28.5 0.0 2.2 1 1 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 CBZ24003.1 - 0.0085 16.4 0.0 3.9 7.8 0.0 2.3 2 0 0 2 2 2 2 Inner membrane component of T3SS, cytoplasmic domain zf-C2HC_2 PF13913.6 CBZ24004.1 - 1.4e-16 59.9 8.3 1.5e-10 40.7 1.7 2.4 2 0 0 2 2 2 2 zinc-finger of a C2HC-type zf-C2H2_4 PF13894.6 CBZ24004.1 - 0.00019 22.0 3.3 0.15 12.9 0.7 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-RING_7 PF02591.15 CBZ24004.1 - 0.0028 17.8 1.5 2.5 8.4 0.1 2.7 2 0 0 2 2 2 2 C4-type zinc ribbon domain zf-Di19 PF05605.12 CBZ24004.1 - 0.0037 17.5 5.7 0.19 12.0 1.2 2.4 2 0 0 2 2 2 2 Drought induced 19 protein (Di19), zinc-binding zf-FPG_IleRS PF06827.14 CBZ24004.1 - 0.0043 16.9 8.3 0.23 11.3 3.6 2.4 2 0 0 2 2 2 2 Zinc finger found in FPG and IleRS RNF220 PF15926.5 CBZ24004.1 - 0.0049 16.5 0.1 0.0081 15.8 0.1 1.3 1 0 0 1 1 1 1 E3 ubiquitin-protein ligase RNF220 Zn-ribbon_8 PF09723.10 CBZ24004.1 - 0.011 15.9 2.8 2.2 8.4 0.5 2.7 2 0 0 2 2 2 0 Zinc ribbon domain zf-C2H2 PF00096.26 CBZ24004.1 - 0.025 15.0 5.4 0.46 11.0 1.5 2.6 2 0 0 2 2 2 0 Zinc finger, C2H2 type zinc_ribbon_9 PF14369.6 CBZ24004.1 - 0.039 14.2 5.1 4 7.8 0.1 2.8 3 0 0 3 3 2 0 zinc-ribbon zf_UBZ PF18439.1 CBZ24004.1 - 0.047 13.3 1.4 8.6 6.1 0.1 2.5 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger zf-CpG_bind_C PF12269.8 CBZ24004.1 - 0.097 12.4 0.4 1.4 8.7 0.0 2.2 2 0 0 2 2 2 0 CpG binding protein zinc finger C terminal domain zf-ribbon_3 PF13248.6 CBZ24004.1 - 0.16 11.4 4.6 2.9 7.4 0.1 2.9 3 0 0 3 3 3 0 zinc-ribbon domain Lar_restr_allev PF14354.6 CBZ24004.1 - 0.36 11.3 4.5 0.97 9.9 0.4 2.7 2 0 0 2 2 2 0 Restriction alleviation protein Lar TRAF6_Z2 PF18048.1 CBZ24004.1 - 0.4 10.8 1.9 5.6 7.1 0.2 2.4 2 0 0 2 2 2 0 TNF receptor-associated factor 6 zinc finger 2 ADK_lid PF05191.14 CBZ24004.1 - 0.47 10.5 4.7 7.9 6.6 0.3 2.5 2 0 0 2 2 2 0 Adenylate kinase, active site lid Prok-RING_1 PF14446.6 CBZ24004.1 - 0.52 10.3 2.7 4.9 7.2 0.3 2.3 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 Rad50_zn_hook PF04423.14 CBZ24004.1 - 0.6 10.0 2.9 18 5.3 0.2 2.4 2 0 0 2 2 2 0 Rad50 zinc hook motif DUF2256 PF10013.9 CBZ24004.1 - 1.6 8.9 5.8 14 5.9 0.1 3.1 3 0 0 3 3 2 0 Uncharacterized protein conserved in bacteria (DUF2256) zinc_ribbon_2 PF13240.6 CBZ24004.1 - 3.6 7.4 9.5 3.3 7.6 0.1 2.7 3 0 0 3 3 2 0 zinc-ribbon domain Zn_Tnp_IS1595 PF12760.7 CBZ24004.1 - 4.3 7.4 6.6 8 6.5 1.2 2.5 2 0 0 2 2 2 0 Transposase zinc-ribbon domain YacG PF03884.14 CBZ24004.1 - 7.4 6.4 6.7 2.5 7.9 0.7 2.5 2 0 0 2 2 2 0 DNA gyrase inhibitor YacG FAD-oxidase_C PF02913.19 CBZ24005.1 - 8.3e-44 150.1 0.6 1.3e-43 149.4 0.6 1.3 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 CBZ24005.1 - 6.7e-37 126.3 0.7 1.4e-36 125.3 0.7 1.6 1 0 0 1 1 1 1 FAD binding domain CPSF_A PF03178.15 CBZ24005.1 - 0.082 12.2 0.0 0.17 11.2 0.0 1.5 1 0 0 1 1 1 0 CPSF A subunit region TTL PF03133.15 CBZ24007.1 - 1.8e-43 148.8 0.0 1.9e-19 69.9 0.0 3.2 2 1 0 2 2 2 2 Tubulin-tyrosine ligase family ATPgrasp_ST PF14397.6 CBZ24007.1 - 0.0026 17.1 0.0 2.2 7.5 0.0 2.4 2 0 0 2 2 2 2 Sugar-transfer associated ATP-grasp HCV_NS5a_C PF12941.7 CBZ24007.1 - 0.04 13.8 2.7 5.5 6.8 0.1 2.5 2 0 0 2 2 2 0 HCV NS5a protein C-terminal region DIOX_N PF14226.6 CBZ24008.1 - 6.2e-35 120.5 0.0 9.4e-35 119.9 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 CBZ24008.1 - 7.6e-25 87.3 0.0 1.5e-24 86.4 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.6 CBZ24009.1 - 1.4e-35 122.6 0.0 2.5e-35 121.8 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 CBZ24009.1 - 3.7e-25 88.3 0.0 6.8e-25 87.5 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily RIO1 PF01163.22 CBZ24010.1 - 5.4e-65 218.5 0.2 1.8e-64 216.8 0.0 1.8 2 0 0 2 2 2 1 RIO1 family Pkinase_fungal PF17667.1 CBZ24010.1 - 0.088 11.6 0.0 0.088 11.6 0.0 1.6 2 0 0 2 2 2 0 Fungal protein kinase APH PF01636.23 CBZ24010.1 - 0.1 12.5 0.1 0.66 9.9 0.1 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family BLOC1S3 PF15753.5 CBZ24010.1 - 0.92 9.6 7.8 1.5 8.9 4.2 2.6 3 0 0 3 3 3 0 Biogenesis of lysosome-related organelles complex 1 subunit 3 CDC45 PF02724.14 CBZ24010.1 - 2 6.6 10.2 2.8 6.1 10.2 1.2 1 0 0 1 1 1 0 CDC45-like protein Sigma70_ner PF04546.13 CBZ24010.1 - 3.3 7.5 10.0 1.3 8.9 7.1 1.7 2 0 0 2 2 2 0 Sigma-70, non-essential region DNA_pol_phi PF04931.13 CBZ24010.1 - 5.4 5.0 8.0 7.8 4.5 8.0 1.1 1 0 0 1 1 1 0 DNA polymerase phi Sec23_trunk PF04811.15 CBZ24012.1 - 3e-42 144.8 0.0 5.5e-42 144.0 0.0 1.3 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_BS PF08033.12 CBZ24012.1 - 8e-21 74.6 0.0 1.6e-20 73.6 0.0 1.5 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.15 CBZ24012.1 - 1.5e-13 50.5 2.3 3.8e-13 49.2 2.3 1.7 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Sec23_helical PF04815.15 CBZ24012.1 - 2.9e-10 39.9 0.0 5.9e-10 38.9 0.0 1.5 1 0 0 1 1 1 1 Sec23/Sec24 helical domain DNA_RNApol_7kD PF03604.13 CBZ24012.1 - 0.067 12.9 0.0 0.17 11.6 0.0 1.7 1 0 0 1 1 1 0 DNA directed RNA polymerase, 7 kDa subunit Sen15 PF09631.10 CBZ24012.1 - 0.11 12.8 0.0 0.34 11.3 0.0 1.7 1 0 0 1 1 1 0 Sen15 protein Remorin_C PF03763.13 CBZ24013.1 - 0.0019 18.0 2.8 0.0039 17.0 2.8 1.6 1 0 0 1 1 1 1 Remorin, C-terminal region DUF3377 PF11857.8 CBZ24013.1 - 5.5 7.0 6.3 27 4.8 0.6 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3377) SNF2_N PF00176.23 CBZ24014.1 - 7.1e-30 103.9 0.0 1.3e-29 103.1 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 CBZ24014.1 - 1.1e-10 41.8 0.0 2.2e-10 40.9 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 CBZ24014.1 - 7.6e-07 29.3 0.0 1.7e-05 24.9 0.0 2.6 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 CBZ24014.1 - 0.00097 18.4 0.0 0.0017 17.6 0.0 1.3 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase SWI2_SNF2 PF18766.1 CBZ24014.1 - 0.0019 17.9 0.1 0.014 15.0 0.0 2.1 2 0 0 2 2 2 1 SWI2/SNF2 ATPase AAA_22 PF13401.6 CBZ24014.1 - 0.045 14.0 0.1 0.26 11.5 0.1 2.4 2 0 0 2 2 2 0 AAA domain TruB_C_2 PF16198.5 CBZ24014.1 - 1 9.6 4.5 0.53 10.5 0.9 2.5 2 0 0 2 2 2 0 tRNA pseudouridylate synthase B C-terminal domain zf-RanBP PF00641.18 CBZ24016.1 - 0.0045 16.3 7.9 0.0045 16.3 7.9 1.7 2 0 0 2 2 2 1 Zn-finger in Ran binding protein and others RRM_1 PF00076.22 CBZ24016.1 - 0.0095 15.7 0.0 0.018 14.9 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TSP9 PF11493.8 CBZ24016.1 - 1.1 10.0 3.8 2.9 8.6 3.8 1.7 1 0 0 1 1 1 0 Thylakoid soluble phosphoprotein TSP9 IPP-2 PF04979.14 CBZ24017.1 - 1.3e-22 81.0 3.5 1.5e-22 80.8 3.5 1.1 1 0 0 1 1 1 1 Protein phosphatase inhibitor 2 (IPP-2) TPR_19 PF14559.6 CBZ24019.1 - 8.7e-13 48.6 15.1 0.0023 18.4 0.3 6.4 5 1 1 6 6 6 4 Tetratricopeptide repeat TPR_2 PF07719.17 CBZ24019.1 - 5.2e-11 41.8 23.1 0.00033 20.5 0.0 9.2 9 0 0 9 9 9 3 Tetratricopeptide repeat TPR_12 PF13424.6 CBZ24019.1 - 1.4e-10 41.3 14.5 0.0091 16.3 0.7 7.0 5 3 2 7 7 7 3 Tetratricopeptide repeat ANAPC3 PF12895.7 CBZ24019.1 - 3.3e-10 40.1 12.8 2.9e-06 27.4 3.8 4.0 3 0 0 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_1 PF00515.28 CBZ24019.1 - 7.8e-08 31.8 17.8 0.15 11.9 0.1 7.8 9 0 0 9 9 9 3 Tetratricopeptide repeat TPR_7 PF13176.6 CBZ24019.1 - 1.7e-05 24.5 8.3 2.5 8.3 0.0 6.9 7 0 0 7 7 6 1 Tetratricopeptide repeat TPR_14 PF13428.6 CBZ24019.1 - 8.9e-05 23.0 14.3 0.073 13.9 0.0 6.8 6 3 3 9 9 6 2 Tetratricopeptide repeat TPR_16 PF13432.6 CBZ24019.1 - 0.00017 22.1 8.4 0.0038 17.8 0.0 4.7 4 2 1 5 5 4 2 Tetratricopeptide repeat HrpB1_HrpK PF09613.10 CBZ24019.1 - 0.00028 20.5 1.7 0.037 13.6 0.0 4.1 2 1 2 4 4 4 1 Bacterial type III secretion protein (HrpB1_HrpK) SRP_TPR_like PF17004.5 CBZ24019.1 - 0.0015 18.5 12.9 0.053 13.6 0.2 4.0 3 1 0 4 4 4 2 Putative TPR-like repeat TPR_3 PF07720.12 CBZ24019.1 - 0.0045 17.0 0.0 0.0045 17.0 0.0 3.9 4 1 2 6 6 3 1 Tetratricopeptide repeat PPR PF01535.20 CBZ24019.1 - 0.016 15.4 7.5 15 6.1 0.1 5.0 5 0 0 5 5 4 0 PPR repeat TPR_8 PF13181.6 CBZ24019.1 - 0.018 15.2 17.0 2.4 8.6 0.1 7.3 9 0 0 9 9 7 0 Tetratricopeptide repeat Sec16_C PF12931.7 CBZ24019.1 - 0.03 14.0 1.4 0.64 9.6 0.3 2.5 2 0 0 2 2 2 0 Sec23-binding domain of Sec16 TPR_20 PF14561.6 CBZ24019.1 - 0.046 14.0 3.9 11 6.4 0.1 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.6 CBZ24019.1 - 0.17 12.6 0.0 0.17 12.6 0.0 7.5 10 0 0 10 10 9 0 Tetratricopeptide repeat TPR_11 PF13414.6 CBZ24019.1 - 0.19 11.4 11.7 1.5 8.6 0.9 4.0 4 1 0 4 4 4 0 TPR repeat Fis1_TPR_C PF14853.6 CBZ24019.1 - 1 9.5 16.3 12 6.1 0.1 5.2 3 1 2 5 5 5 0 Fis1 C-terminal tetratricopeptide repeat TPR_17 PF13431.6 CBZ24019.1 - 1.7 9.2 5.8 27 5.4 0.3 4.7 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_10 PF13374.6 CBZ24019.1 - 8.8 6.4 8.5 21 5.1 0.2 5.1 7 0 0 7 7 6 0 Tetratricopeptide repeat RNA_pol_A_bac PF01000.26 CBZ24020.1 - 1.8e-19 70.2 0.0 3.4e-19 69.3 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.24 CBZ24020.1 - 1.6e-16 59.5 0.0 2.8e-16 58.7 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Fer4_9 PF13187.6 CBZ24020.1 - 0.059 13.5 1.0 0.059 13.5 1.0 2.1 2 0 0 2 2 2 0 4Fe-4S dicluster domain IQ PF00612.27 CBZ24021.1 - 0.00055 19.5 2.0 0.00055 19.5 2.0 3.3 3 0 0 3 3 3 2 IQ calmodulin-binding motif RPN1_RPN2_N PF17781.1 CBZ24022.1 - 1.5e-76 257.7 0.2 4.3e-76 256.3 0.1 1.8 3 0 0 3 3 3 1 RPN1/RPN2 N-terminal domain PC_rep PF01851.22 CBZ24022.1 - 5.5e-23 80.2 14.9 1.8e-05 24.9 0.0 8.4 9 0 0 9 9 9 5 Proteasome/cyclosome repeat RPN1_C PF18051.1 CBZ24022.1 - 2.6e-18 65.8 0.0 5.1e-18 64.9 0.0 1.4 1 0 0 1 1 1 1 26S proteasome non-ATPase regulatory subunit RPN1 C-terminal HEAT_2 PF13646.6 CBZ24022.1 - 0.0019 18.5 5.4 0.18 12.2 0.2 4.5 4 2 0 4 4 4 1 HEAT repeats HEAT_EZ PF13513.6 CBZ24022.1 - 0.019 15.4 3.5 3.2 8.4 0.1 4.7 5 0 0 5 5 5 0 HEAT-like repeat IFRD PF05004.13 CBZ24022.1 - 0.02 14.0 0.4 0.055 12.6 0.1 1.9 2 0 0 2 2 2 0 Interferon-related developmental regulator (IFRD) PhrC_PhrF PF11131.8 CBZ24022.1 - 0.079 12.6 0.3 0.28 10.8 0.3 2.0 1 0 0 1 1 1 0 Rap-phr extracellular signalling DHR-2 PF06920.13 CBZ24023.1 - 9.7e-20 70.7 3.0 3.2e-15 55.8 0.3 2.7 2 0 0 2 2 2 2 Dock homology region 2 DOCK-C2 PF14429.6 CBZ24023.1 - 7.9e-17 61.7 0.0 1.5e-16 60.8 0.0 1.4 1 0 0 1 1 1 1 C2 domain in Dock180 and Zizimin proteins Fibrinogen_BP PF08017.11 CBZ24023.1 - 2.2e-09 36.3 111.0 2.2e-09 36.3 111.0 4.0 1 1 2 3 3 3 2 Fibrinogen binding protein tify PF06200.14 CBZ24024.1 - 0.0004 19.6 0.2 0.73 9.2 0.0 2.5 2 0 0 2 2 2 2 tify domain Ras PF00071.22 CBZ24025.1 - 5.8e-35 120.3 0.2 6.7e-35 120.1 0.2 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CBZ24025.1 - 2.6e-18 66.4 0.0 3.6e-18 65.9 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CBZ24025.1 - 1e-11 44.6 0.0 1.4e-11 44.2 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 CBZ24025.1 - 1e-06 28.3 0.1 1.4e-06 27.9 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 CBZ24025.1 - 0.0012 18.9 0.0 0.0019 18.3 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase PduV-EutP PF10662.9 CBZ24025.1 - 0.0069 16.1 0.0 0.14 11.9 0.0 2.1 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation G-alpha PF00503.20 CBZ24025.1 - 0.0076 15.4 0.0 0.073 12.2 0.0 2.1 1 1 1 2 2 2 1 G-protein alpha subunit cobW PF02492.19 CBZ24025.1 - 0.14 11.7 1.0 0.8 9.3 0.4 2.1 1 1 1 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain RsgA_GTPase PF03193.16 CBZ24025.1 - 0.16 11.9 0.1 0.25 11.2 0.0 1.4 2 0 0 2 2 2 0 RsgA GTPase SNARE PF05739.19 CBZ24027.1 - 3.6e-06 26.9 0.4 9.3e-06 25.5 0.4 1.7 1 0 0 1 1 1 1 SNARE domain DUF1664 PF07889.12 CBZ24027.1 - 0.0029 17.7 5.4 0.66 10.0 0.4 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF1664) Syntaxin_2 PF14523.6 CBZ24027.1 - 0.031 14.6 11.9 0.032 14.6 2.0 2.6 2 1 0 2 2 2 0 Syntaxin-like protein Dynactin_p22 PF07426.11 CBZ24027.1 - 0.032 14.1 2.5 0.038 13.9 0.2 2.1 2 0 0 2 2 2 0 Dynactin subunit p22 DUF1574 PF07611.11 CBZ24027.1 - 0.074 12.4 0.6 0.13 11.5 0.1 1.5 1 1 0 2 2 2 0 Protein of unknown function (DUF1574) LMBR1 PF04791.16 CBZ24027.1 - 0.13 11.1 6.1 0.17 10.7 6.1 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Synaptobrevin PF00957.21 CBZ24027.1 - 0.21 11.4 5.8 0.18 11.6 2.1 2.3 2 0 0 2 2 2 0 Synaptobrevin BLOC1S3 PF15753.5 CBZ24027.1 - 0.37 10.9 13.1 0.15 12.2 0.7 3.1 1 1 2 3 3 3 0 Biogenesis of lysosome-related organelles complex 1 subunit 3 Peroxin-13_N PF04088.13 CBZ24027.1 - 0.53 10.6 4.8 1.5 9.1 0.1 2.8 2 1 1 3 3 3 0 Peroxin 13, N-terminal region DUF948 PF06103.11 CBZ24027.1 - 0.61 10.4 3.9 14 6.0 0.2 3.0 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) RmuC PF02646.16 CBZ24027.1 - 1 8.4 10.1 0.077 12.1 1.1 2.8 2 1 1 3 3 3 0 RmuC family RhoGAP PF00620.27 CBZ24027.1 - 2 8.3 5.6 1 9.2 1.4 2.6 1 1 1 2 2 2 0 RhoGAP domain Jnk-SapK_ap_N PF09744.9 CBZ24027.1 - 4.7 7.4 15.7 0.64 10.2 5.8 2.6 1 1 2 3 3 3 0 JNK_SAPK-associated protein-1 tRNA-synt_1b PF00579.25 CBZ24028.1 - 2.6e-20 73.0 0.0 1.1e-19 70.9 0.0 1.9 1 1 0 1 1 1 1 tRNA synthetases class I (W and Y) ATG11 PF10377.9 CBZ24028.1 - 0.11 12.5 0.0 0.27 11.3 0.0 1.6 1 0 0 1 1 1 0 Autophagy-related protein 11 GSP_synth PF03738.14 CBZ24030.1 - 0.1 11.7 0.0 0.15 11.2 0.0 1.3 1 0 0 1 1 1 0 Glutathionylspermidine synthase preATP-grasp Ribosomal_L3 PF00297.22 CBZ24031.1 - 9.7e-08 31.4 0.1 1.7e-07 30.6 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L3 PWWP PF00855.17 CBZ24031.1 - 0.049 14.1 0.3 0.1 13.0 0.3 1.5 1 0 0 1 1 1 0 PWWP domain TPR_2 PF07719.17 CBZ24031.1 - 0.16 12.1 0.8 0.41 10.9 0.8 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat SPT16 PF08644.11 CBZ24032.1 - 1.2e-31 110.0 1.1 3.2e-31 108.5 0.0 2.1 2 0 0 2 2 2 1 FACT complex subunit (SPT16/CDC68) Peptidase_M24 PF00557.24 CBZ24032.1 - 8.1e-15 55.1 0.0 2.1e-14 53.7 0.0 1.7 1 0 0 1 1 1 1 Metallopeptidase family M24 Rtt106 PF08512.12 CBZ24032.1 - 4.2e-09 36.7 0.0 1.8e-08 34.7 0.0 2.1 2 0 0 2 2 2 1 Histone chaperone Rttp106-like BUD22 PF09073.10 CBZ24032.1 - 3.4 6.9 17.0 6.1 6.1 17.0 1.3 1 0 0 1 1 1 0 BUD22 Nop14 PF04147.12 CBZ24032.1 - 3.6 5.7 15.4 5.7 5.0 15.4 1.2 1 0 0 1 1 1 0 Nop14-like family ECH_1 PF00378.20 CBZ24033.1 - 1.1e-37 129.7 0.0 1.4e-37 129.4 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 CBZ24033.1 - 1.8e-10 40.8 0.0 2.2e-10 40.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase CLP_protease PF00574.23 CBZ24033.1 - 0.16 11.9 0.1 0.71 9.7 0.0 2.0 2 0 0 2 2 2 0 Clp protease SMC_N PF02463.19 CBZ24034.1 - 1.9e-62 210.6 1.6 2.7e-62 210.1 1.6 1.2 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 CBZ24034.1 - 1e-24 87.1 0.0 3e-24 85.6 0.0 1.9 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.6 CBZ24034.1 - 1.4e-14 54.6 0.2 7.2e-06 26.0 0.1 3.1 2 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 CBZ24034.1 - 2e-14 54.1 18.5 2.8e-11 43.7 14.0 3.3 2 1 0 2 2 2 2 AAA ATPase domain AAA_23 PF13476.6 CBZ24034.1 - 1.3e-07 32.3 34.4 1.3e-07 32.3 34.4 5.2 2 2 0 2 2 2 1 AAA domain AAA_29 PF13555.6 CBZ24034.1 - 0.0036 17.0 0.0 0.0082 15.9 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain ABC_tran PF00005.27 CBZ24034.1 - 0.5 10.9 25.3 0.33 11.5 0.1 6.0 4 3 0 4 4 4 0 ABC transporter DUF4250 PF14056.6 CBZ24034.1 - 0.56 10.2 5.8 14 5.8 0.1 4.3 2 1 1 3 3 3 0 Domain of unknown function (DUF4250) DUF2721 PF11026.8 CBZ24034.1 - 3.4 7.6 6.0 13 5.7 0.0 4.0 3 1 0 3 3 3 0 Protein of unknown function (DUF2721) Synaptobrevin PF00957.21 CBZ24036.1 - 3e-30 103.9 4.9 5.1e-30 103.1 4.9 1.4 1 0 0 1 1 1 1 Synaptobrevin EMP24_GP25L PF01105.24 CBZ24036.1 - 0.0063 16.5 0.0 0.01 15.8 0.0 1.3 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD FtsK_SpoIIIE PF01580.18 CBZ24036.1 - 0.029 13.7 0.3 0.046 13.1 0.3 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family DUF4844 PF16133.5 CBZ24036.1 - 0.029 14.9 1.0 0.067 13.7 1.0 1.7 2 1 0 2 2 2 0 Domain of unknown function (DUF4844) Longin PF13774.6 CBZ24036.1 - 0.076 13.1 0.0 0.16 12.1 0.0 1.5 1 0 0 1 1 1 0 Regulated-SNARE-like domain Baculo_11_kDa PF06143.11 CBZ24036.1 - 2.1 7.9 7.3 4.4 6.9 6.8 1.7 1 1 0 1 1 1 0 Baculovirus 11 kDa family His_Phos_1 PF00300.22 CBZ24039.1 - 7.4e-39 133.4 0.0 8.2e-39 133.3 0.0 1.0 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) ASCH PF04266.14 CBZ24040.1 - 3e-17 63.2 0.0 1.9e-16 60.5 0.0 2.3 2 0 0 2 2 2 1 ASCH domain zf-C2HC5 PF06221.13 CBZ24040.1 - 0.00016 21.6 9.4 0.00032 20.6 9.4 1.5 1 0 0 1 1 1 1 Putative zinc finger motif, C2HC5-type DUF4236 PF14020.6 CBZ24040.1 - 0.042 14.4 3.7 0.093 13.3 3.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4236) DEAD PF00270.29 CBZ24041.1 - 3.4e-39 134.4 0.0 5.2e-39 133.8 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CBZ24041.1 - 6.1e-23 81.3 0.0 2.1e-22 79.6 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 CBZ24041.1 - 2.7e-05 24.2 0.0 5.9e-05 23.1 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 CBZ24041.1 - 0.00026 21.3 0.0 0.00076 19.8 0.0 1.9 1 1 0 1 1 1 1 AAA domain SecA_DEAD PF07517.14 CBZ24041.1 - 0.02 14.2 0.0 0.31 10.3 0.0 2.3 2 0 0 2 2 2 0 SecA DEAD-like domain Adaptin_N PF01602.20 CBZ24042.1 - 1.4e-80 271.4 0.0 1.8e-80 271.0 0.0 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 CBZ24042.1 - 3.8e-10 40.1 0.0 2.5e-06 27.6 0.0 2.3 1 1 1 2 2 2 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 CBZ24042.1 - 0.00048 20.5 3.2 1.3 9.4 0.2 3.9 3 1 1 4 4 4 2 HEAT repeats RTP1_C1 PF10363.9 CBZ24042.1 - 0.028 14.6 0.0 0.13 12.5 0.0 2.0 2 0 0 2 2 2 0 Required for nuclear transport of RNA pol II C-terminus 1 HrpB1_HrpK PF09613.10 CBZ24042.1 - 0.034 13.8 0.0 0.1 12.3 0.0 1.8 1 0 0 1 1 1 0 Bacterial type III secretion protein (HrpB1_HrpK) Vac14_Fab1_bd PF12755.7 CBZ24042.1 - 0.055 14.1 0.0 1.8 9.2 0.0 2.6 2 0 0 2 2 2 0 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.6 CBZ24042.1 - 0.11 13.0 7.9 0.29 11.7 0.1 4.2 4 0 0 4 4 4 0 HEAT-like repeat HEAT PF02985.22 CBZ24042.1 - 0.17 12.3 10.8 2.7 8.5 0.1 5.5 5 0 0 5 5 5 0 HEAT repeat DSPc PF00782.20 CBZ24043.1 - 3.8e-28 97.9 0.0 7.3e-28 97.0 0.0 1.5 1 1 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase2 PF03162.13 CBZ24043.1 - 0.0025 17.4 0.1 1.6 8.3 0.0 2.9 3 0 0 3 3 3 2 Tyrosine phosphatase family Y_phosphatase PF00102.27 CBZ24043.1 - 0.033 13.7 0.1 0.068 12.7 0.0 1.5 2 0 0 2 2 2 0 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 CBZ24043.1 - 0.091 12.9 0.0 0.16 12.0 0.0 1.4 1 0 0 1 1 1 0 Inositol hexakisphosphate SCP-1 PF05483.12 CBZ24044.1 - 0.0026 15.9 7.0 0.0037 15.3 7.0 1.1 1 0 0 1 1 1 1 Synaptonemal complex protein 1 (SCP-1) Cnn_1N PF07989.11 CBZ24044.1 - 0.014 15.6 2.4 0.014 15.6 2.4 3.1 4 0 0 4 4 2 0 Centrosomin N-terminal motif 1 HALZ PF02183.18 CBZ24044.1 - 0.051 13.8 0.4 0.051 13.8 0.4 3.8 4 0 0 4 4 4 0 Homeobox associated leucine zipper Seryl_tRNA_N PF02403.22 CBZ24044.1 - 0.15 12.3 14.5 0.073 13.3 4.2 3.4 3 1 1 4 4 4 0 Seryl-tRNA synthetase N-terminal domain Macoilin PF09726.9 CBZ24044.1 - 0.26 9.8 8.8 0.4 9.2 8.8 1.2 1 0 0 1 1 1 0 Macoilin family GAS PF13851.6 CBZ24044.1 - 0.27 10.5 15.1 0.18 11.1 10.3 2.5 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding SYCE1 PF15233.6 CBZ24044.1 - 0.62 10.1 13.7 1.8 8.6 13.7 1.8 1 0 0 1 1 1 0 Synaptonemal complex central element protein 1 Spc7 PF08317.11 CBZ24044.1 - 1.1 8.1 18.9 3.9 6.3 8.2 2.8 2 1 1 3 3 3 0 Spc7 kinetochore protein Jnk-SapK_ap_N PF09744.9 CBZ24044.1 - 1.8 8.8 20.3 0.73 10.0 16.0 2.5 2 1 0 2 2 2 0 JNK_SAPK-associated protein-1 DUF1664 PF07889.12 CBZ24044.1 - 3.5 7.7 10.0 8.5 6.4 2.4 3.9 2 1 1 4 4 4 0 Protein of unknown function (DUF1664) OmpH PF03938.14 CBZ24044.1 - 3.6 7.9 10.1 3.4 8.0 8.2 2.0 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) WXG100 PF06013.12 CBZ24044.1 - 3.7 7.9 8.4 59 4.0 1.8 4.0 3 1 0 3 3 3 0 Proteins of 100 residues with WXG Atg14 PF10186.9 CBZ24044.1 - 4.7 6.2 16.9 7.7 5.5 2.1 2.2 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 FapA PF03961.13 CBZ24044.1 - 6 5.4 5.4 6.2 5.3 4.3 1.4 1 1 0 1 1 1 0 Flagellar Assembly Protein A COG2 PF06148.11 CBZ24044.1 - 8.3 6.5 11.8 1 9.4 0.8 3.4 2 1 1 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 YabA PF06156.13 CBZ24044.1 - 9.1 7.0 10.5 32 5.2 1.2 3.2 1 1 2 3 3 3 0 Initiation control protein YabA Phage_GP20 PF06810.11 CBZ24044.1 - 10 5.9 11.8 1.2 9.0 7.1 1.9 2 0 0 2 2 2 0 Phage minor structural protein GP20 FYVE_2 PF02318.16 CBZ24046.1 - 0.0014 18.8 3.8 0.0025 18.0 3.8 1.3 1 0 0 1 1 1 1 FYVE-type zinc finger EF-hand_6 PF13405.6 CBZ24047.1 - 0.021 14.7 0.2 0.074 13.0 0.0 2.0 2 0 0 2 2 2 0 EF-hand domain EF-hand_7 PF13499.6 CBZ24047.1 - 0.23 11.9 0.0 1 9.9 0.0 2.0 2 1 0 2 2 2 0 EF-hand domain pair ERCC4 PF02732.15 CBZ24048.1 - 2.1e-15 57.2 0.0 1.1e-14 54.9 0.0 2.1 2 0 0 2 2 2 1 ERCC4 domain PIG-H PF10181.9 CBZ24049.1 - 1.6e-10 40.7 0.2 2.7e-10 40.0 0.2 1.4 1 0 0 1 1 1 1 GPI-GlcNAc transferase complex, PIG-H component VirB3 PF05101.13 CBZ24049.1 - 0.4 10.9 4.9 0.25 11.6 0.5 2.4 2 0 0 2 2 2 0 Type IV secretory pathway, VirB3-like protein LRR_4 PF12799.7 CBZ24051.1 - 1.6e-10 41.1 1.9 0.00044 20.6 0.0 7.2 5 2 4 9 9 9 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CBZ24051.1 - 2.7e-05 23.8 0.1 2.3 8.1 0.2 4.8 4 2 0 4 4 4 2 Leucine rich repeat LRR_6 PF13516.6 CBZ24051.1 - 0.37 11.0 6.3 2.6 8.3 0.0 4.3 4 0 0 4 4 4 0 Leucine Rich repeat LRR_1 PF00560.33 CBZ24051.1 - 0.94 10.3 10.7 24 6.0 0.0 6.0 7 0 0 7 7 7 0 Leucine Rich Repeat Hexapep PF00132.24 CBZ24052.1 - 1.2e-13 50.1 3.4 3.8e-05 23.2 0.0 3.3 2 1 2 4 4 4 4 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 CBZ24052.1 - 6.1 6.7 10.9 0.67 9.8 0.5 3.1 2 1 2 4 4 4 0 Hexapeptide repeat of succinyl-transferase Exo_endo_phos PF03372.23 CBZ24054.1 - 3.4e-14 52.9 0.0 9e-14 51.5 0.0 1.6 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family DUF3301 PF11743.8 CBZ24054.1 - 0.25 11.0 2.5 0.57 9.9 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3301) ThiF PF00899.21 CBZ24056.1 - 7.6e-58 195.7 0.0 6.8e-57 192.6 0.0 2.3 1 1 0 1 1 1 1 ThiF family UAE_UbL PF14732.6 CBZ24056.1 - 1.8e-18 66.9 0.0 3.2e-18 66.1 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain UBA_e1_thiolCys PF10585.9 CBZ24056.1 - 6.3e-05 23.0 0.0 0.044 13.7 0.0 2.3 2 0 0 2 2 2 2 Ubiquitin-activating enzyme active site PglD_N PF17836.1 CBZ24056.1 - 0.19 12.4 0.0 0.42 11.3 0.0 1.6 1 0 0 1 1 1 0 PglD N-terminal domain ABC1 PF03109.16 CBZ24057.1 - 4.4e-27 94.6 0.0 1.2e-26 93.2 0.0 1.8 2 0 0 2 2 2 1 ABC1 family APH PF01636.23 CBZ24057.1 - 0.00018 21.5 2.1 0.0005 20.1 0.3 2.6 2 1 0 2 2 2 1 Phosphotransferase enzyme family Ribosomal_L9_N PF01281.19 CBZ24058.1 - 3.7e-06 26.4 0.0 7.4e-06 25.4 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L9, N-terminal domain JHY PF15261.6 CBZ24060.1 - 2e-08 35.0 6.3 0.0026 18.5 1.5 3.3 2 1 0 2 2 2 2 Jhy protein Ribosomal_L2_C PF03947.18 CBZ24062.1 - 2.1e-21 76.4 0.1 3.5e-21 75.7 0.1 1.3 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Sod_Fe_C PF02777.18 CBZ24063.1 - 1.9e-35 121.1 0.3 5.1e-35 119.7 0.1 1.8 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.22 CBZ24063.1 - 2.4e-19 69.6 0.0 6e-19 68.3 0.0 1.7 1 1 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain Isochorismatase PF00857.20 CBZ24064.1 - 4.9e-14 52.9 0.0 3e-13 50.3 0.0 2.0 1 1 0 1 1 1 1 Isochorismatase family Isochorismatase PF00857.20 CBZ24065.1 - 1.5e-11 44.8 0.3 3.2e-11 43.7 0.3 1.5 1 0 0 1 1 1 1 Isochorismatase family Isochorismatase PF00857.20 CBZ24066.1 - 1.2e-12 48.4 0.3 5.4e-12 46.2 0.3 1.8 1 1 0 1 1 1 1 Isochorismatase family zf-Tim10_DDP PF02953.15 CBZ24067.1 - 1.9e-11 43.4 0.1 2.6e-11 43.0 0.1 1.2 1 0 0 1 1 1 1 Tim10/DDP family zinc finger Cas_Cas1 PF01867.16 CBZ24068.1 - 0.013 14.7 0.6 0.044 12.9 0.0 2.1 3 0 0 3 3 3 0 CRISPR associated protein Cas1 APG6 PF04111.12 CBZ24074.1 - 5.3e-15 55.8 0.0 1.4e-05 25.1 0.0 3.7 3 1 0 3 3 3 3 Apg6 BARA domain WD40 PF00400.32 CBZ24075.1 - 9.9e-23 80.0 18.6 6.1e-06 26.9 0.1 10.3 10 1 0 10 10 10 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBZ24075.1 - 4.4e-15 55.8 0.3 0.0029 17.9 0.0 6.5 3 1 3 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 CBZ24075.1 - 0.00012 21.6 0.0 0.17 11.2 0.0 4.0 4 1 0 5 5 5 1 WD40-like domain PQQ_2 PF13360.6 CBZ24075.1 - 0.00033 20.3 0.7 0.00033 20.3 0.7 2.7 3 0 0 3 3 3 1 PQQ-like domain BBS2_Mid PF14783.6 CBZ24075.1 - 0.00045 20.2 0.1 1.2 9.3 0.0 4.9 6 1 0 6 6 6 1 Ciliary BBSome complex subunit 2, middle region Nup160 PF11715.8 CBZ24075.1 - 0.0014 17.4 3.2 0.73 8.4 0.1 4.0 3 1 1 5 5 5 2 Nucleoporin Nup120/160 RAB3GAP2_N PF14655.6 CBZ24075.1 - 0.0046 16.3 0.1 1.6 7.9 0.0 3.5 3 0 0 3 3 3 1 Rab3 GTPase-activating protein regulatory subunit N-terminus NUC202 PF08166.12 CBZ24075.1 - 7.5 6.7 6.4 8.2 6.6 0.1 3.4 3 0 0 3 3 3 0 NUC202 domain OAD_gamma PF04277.13 CBZ24077.1 - 0.61 10.7 2.7 2.9 8.6 2.7 2.2 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain Peptidase_S24 PF00717.23 CBZ24079.1 - 1e-10 41.4 0.0 1.8e-10 40.6 0.0 1.4 1 0 0 1 1 1 1 Peptidase S24-like Rad60-SLD PF11976.8 CBZ24081.1 - 1.3e-24 85.8 0.1 1.6e-24 85.5 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 CBZ24081.1 - 7.1e-11 41.7 0.0 8.6e-11 41.4 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin family HTH_41 PF14502.6 CBZ24081.1 - 0.13 11.9 0.2 0.39 10.4 0.0 1.9 2 0 0 2 2 2 0 Helix-turn-helix domain Pribosyl_synth PF14572.6 CBZ24085.1 - 2.1e-20 73.6 3.3 2.8e-20 73.1 0.4 2.4 3 0 0 3 3 3 1 Phosphoribosyl synthetase-associated domain Pribosyltran_N PF13793.6 CBZ24085.1 - 4.1e-18 65.4 0.6 1.9e-17 63.2 0.0 2.4 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase SPX PF03105.19 CBZ24085.1 - 1.7e-05 24.9 0.3 1.7e-05 24.9 0.3 3.0 3 0 0 3 3 3 1 SPX domain Pribosyltran PF00156.27 CBZ24085.1 - 0.00032 20.2 0.3 0.009 15.5 0.1 2.8 2 1 1 3 3 3 1 Phosphoribosyl transferase domain Pkinase_Tyr PF07714.17 CBZ24086.1 - 2.3e-06 27.1 0.0 0.0034 16.7 0.0 2.5 3 0 0 3 3 3 2 Protein tyrosine kinase Pkinase PF00069.25 CBZ24086.1 - 0.00016 21.1 0.0 0.15 11.4 0.0 2.5 2 0 0 2 2 2 2 Protein kinase domain Kelch_1 PF01344.25 CBZ24086.1 - 0.057 13.0 0.4 6.5 6.4 0.0 3.5 3 0 0 3 3 3 0 Kelch motif Pkinase PF00069.25 CBZ24087.1 - 9.1e-36 123.6 0.0 5.8e-23 81.6 0.0 3.2 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ24087.1 - 4.4e-16 58.9 0.0 6.1e-06 25.7 0.0 3.3 3 1 0 3 3 3 3 Protein tyrosine kinase APH PF01636.23 CBZ24087.1 - 0.0027 17.7 0.2 0.0069 16.3 0.2 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family Toxin_8 PF07365.12 CBZ24087.1 - 0.22 11.7 7.0 0.098 12.9 0.3 3.3 2 0 0 2 2 2 0 Alpha conotoxin precursor Complex1_LYR PF05347.15 CBZ24088.1 - 0.0018 18.3 0.7 0.0098 15.9 0.8 2.1 2 0 0 2 2 2 1 Complex 1 protein (LYR family) CMAS PF02353.20 CBZ24089.1 - 4.9e-76 255.6 0.0 6.6e-76 255.2 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_25 PF13649.6 CBZ24089.1 - 7.3e-17 61.9 0.0 1.6e-16 60.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CBZ24089.1 - 2e-12 47.6 0.0 4e-12 46.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 CBZ24089.1 - 8.3e-12 45.2 0.0 1.7e-11 44.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CBZ24089.1 - 1.3e-08 35.5 0.0 4.1e-08 33.9 0.0 1.8 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CBZ24089.1 - 5.8e-06 26.2 0.0 1.1e-05 25.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 CBZ24089.1 - 7.4e-06 25.6 0.0 3.3e-05 23.5 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase small domain MetW PF07021.12 CBZ24089.1 - 0.0014 18.3 0.0 0.0045 16.6 0.0 1.8 2 0 0 2 2 2 1 Methionine biosynthesis protein MetW RrnaAD PF00398.20 CBZ24089.1 - 0.0019 17.3 0.0 0.0031 16.6 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_32 PF13679.6 CBZ24089.1 - 0.0025 17.8 0.0 0.0047 16.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain NodS PF05401.11 CBZ24089.1 - 0.0027 17.3 0.0 0.0047 16.6 0.0 1.3 1 0 0 1 1 1 1 Nodulation protein S (NodS) FtsJ PF01728.19 CBZ24089.1 - 0.003 17.7 0.0 0.005 17.0 0.0 1.4 1 0 0 1 1 1 1 FtsJ-like methyltransferase PCMT PF01135.19 CBZ24089.1 - 0.004 16.9 0.0 0.0066 16.2 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) TehB PF03848.14 CBZ24089.1 - 0.0059 16.0 0.0 0.01 15.2 0.0 1.3 1 0 0 1 1 1 1 Tellurite resistance protein TehB eIF-5_eIF-2B PF01873.17 CBZ24090.1 - 3.6e-29 101.0 0.7 6.8e-29 100.1 0.7 1.4 1 0 0 1 1 1 1 Domain found in IF2B/IF5 Cytochrom_c3_2 PF14537.6 CBZ24090.1 - 0.047 14.2 0.4 0.21 12.1 0.4 2.1 1 0 0 1 1 1 0 Cytochrome c3 Img2 PF05046.14 CBZ24091.1 - 1.2e-05 25.6 0.0 1.9e-05 24.9 0.0 1.4 1 0 0 1 1 1 1 Mitochondrial large subunit ribosomal protein (Img2) ASFV_J13L PF05568.11 CBZ24093.1 - 0.0021 17.8 0.2 0.0029 17.4 0.2 1.2 1 0 0 1 1 1 1 African swine fever virus J13L protein TMEM154 PF15102.6 CBZ24093.1 - 0.0063 16.4 0.0 0.011 15.6 0.0 1.5 1 1 1 2 2 2 1 TMEM154 protein family Miga PF10265.9 CBZ24093.1 - 0.057 12.4 0.0 0.068 12.1 0.0 1.0 1 0 0 1 1 1 0 Mitoguardin Mtp PF03821.16 CBZ24093.1 - 0.16 11.5 0.3 0.21 11.2 0.3 1.1 1 0 0 1 1 1 0 Golgi 4-transmembrane spanning transporter OATP PF03137.20 CBZ24095.1 - 0.001 17.5 0.0 0.0011 17.4 0.0 1.1 1 0 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family UPF0370 PF13980.6 CBZ24095.1 - 0.021 14.8 0.2 0.029 14.4 0.2 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0370) YMF19 PF02326.15 CBZ24095.1 - 0.041 14.7 0.0 0.054 14.3 0.0 1.3 1 0 0 1 1 1 0 Plant ATP synthase F0 TssO PF17561.2 CBZ24095.1 - 0.071 13.2 0.1 0.1 12.7 0.1 1.1 1 0 0 1 1 1 0 Type VI secretion system, TssO DUF4148 PF13663.6 CBZ24095.1 - 0.085 13.0 4.1 0.64 10.2 0.3 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4148) DUF4736 PF15883.5 CBZ24095.1 - 0.087 12.5 0.2 0.29 10.8 0.2 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4736) DUF3357 PF11837.8 CBZ24095.1 - 0.089 13.3 1.0 1.7 9.2 0.0 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF3357) MAP17 PF15807.5 CBZ24095.1 - 0.1 12.8 0.0 0.15 12.3 0.0 1.2 1 0 0 1 1 1 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 HemY_N PF07219.13 CBZ24095.1 - 0.12 12.5 1.8 0.18 12.0 0.2 1.9 2 0 0 2 2 2 0 HemY protein N-terminus Phage_holin_3_6 PF07332.11 CBZ24095.1 - 0.14 12.2 5.6 0.42 10.7 5.4 1.7 1 1 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III Spore_YhaL PF14147.6 CBZ24095.1 - 0.18 11.5 2.7 0.29 10.8 2.7 1.2 1 0 0 1 1 1 0 Sporulation protein YhaL Amastin PF07344.11 CBZ24098.1 - 1.6e-05 24.8 7.4 3.1e-05 23.8 7.4 1.5 1 0 0 1 1 1 1 Amastin surface glycoprotein DnaJ PF00226.31 CBZ24099.1 - 1.4e-15 57.1 0.3 2.6e-15 56.3 0.3 1.5 1 0 0 1 1 1 1 DnaJ domain Pkinase PF00069.25 CBZ24100.1 - 7.9e-17 61.5 0.0 1.6e-16 60.5 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ24100.1 - 1e-12 47.9 0.0 2.5e-12 46.6 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Seadorna_VP7 PF07387.11 CBZ24100.1 - 0.011 14.8 0.0 0.023 13.8 0.0 1.4 1 0 0 1 1 1 0 Seadornavirus VP7 AAA_16 PF13191.6 CBZ24101.1 - 8e-06 26.3 0.4 3.7e-05 24.2 0.0 2.3 3 0 0 3 3 3 1 AAA ATPase domain ATPase_2 PF01637.18 CBZ24101.1 - 0.00066 19.7 0.0 0.0015 18.5 0.0 1.6 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea AAA_22 PF13401.6 CBZ24101.1 - 0.0012 19.1 0.5 0.012 15.9 0.0 2.6 3 0 0 3 3 3 1 AAA domain AAA_14 PF13173.6 CBZ24101.1 - 0.0027 17.8 0.0 0.0057 16.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 CBZ24101.1 - 0.0097 15.7 0.9 0.012 15.4 0.0 1.6 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase DUF815 PF05673.13 CBZ24101.1 - 0.022 13.9 0.0 0.058 12.6 0.0 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF815) cobW PF02492.19 CBZ24101.1 - 0.09 12.4 0.0 0.2 11.2 0.0 1.6 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain SMC_N PF02463.19 CBZ24101.1 - 0.18 11.2 0.0 3.7 6.9 0.0 2.2 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 CBZ24102.1 - 0.00016 22.1 0.0 0.00038 20.9 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 CBZ24102.1 - 0.0085 16.4 0.1 0.053 13.8 0.1 2.3 1 1 0 1 1 1 1 AAA domain ATPase_2 PF01637.18 CBZ24102.1 - 0.01 15.8 0.0 0.027 14.4 0.0 1.6 2 0 0 2 2 2 1 ATPase domain predominantly from Archaea ATPase PF06745.13 CBZ24102.1 - 0.052 12.9 0.0 0.097 12.0 0.0 1.3 1 0 0 1 1 1 0 KaiC Zeta_toxin PF06414.12 CBZ24102.1 - 0.056 12.7 0.0 0.12 11.6 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin Ub-Mut7C PF14451.6 CBZ24102.1 - 0.16 11.9 0.0 0.52 10.2 0.0 1.8 2 0 0 2 2 2 0 Mut7-C ubiquitin DUF2624 PF11116.8 CBZ24102.1 - 0.19 12.6 0.0 0.41 11.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2624) Amastin PF07344.11 CBZ24104.1 - 1.9e-52 177.2 15.8 2.3e-52 176.9 15.8 1.1 1 0 0 1 1 1 1 Amastin surface glycoprotein MMPL PF03176.15 CBZ24104.1 - 6.6 5.5 6.3 12 4.8 6.3 1.3 1 0 0 1 1 1 0 MMPL family Amastin PF07344.11 CBZ24105.1 - 3.4e-43 147.2 7.9 4e-43 146.9 7.9 1.0 1 0 0 1 1 1 1 Amastin surface glycoprotein DUF4407 PF14362.6 CBZ24105.1 - 1.2 8.4 5.0 1.5 8.1 5.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF3087 PF11286.8 CBZ24105.1 - 1.9 7.9 4.2 0.32 10.4 0.6 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3087) Adeno_E3_CR2 PF02439.15 CBZ24105.1 - 4 7.3 8.6 11 5.8 0.2 2.4 2 0 0 2 2 2 0 Adenovirus E3 region protein CR2 Amastin PF07344.11 CBZ24106.1 - 1e-49 168.4 6.9 1.2e-49 168.1 6.9 1.0 1 0 0 1 1 1 1 Amastin surface glycoprotein DUF4407 PF14362.6 CBZ24106.1 - 1 8.7 3.2 1.5 8.1 3.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Amastin PF07344.11 CBZ24107.1 - 4.9e-52 175.9 12.9 5.8e-52 175.6 12.9 1.1 1 0 0 1 1 1 1 Amastin surface glycoprotein DUF3087 PF11286.8 CBZ24107.1 - 1.3 8.5 3.7 0.33 10.4 0.7 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3087) Amastin PF07344.11 CBZ24108.1 - 5.5e-53 179.0 7.4 6.5e-53 178.7 7.4 1.1 1 0 0 1 1 1 1 Amastin surface glycoprotein DUF4525 PF15027.6 CBZ24108.1 - 0.23 11.2 1.9 0.69 9.6 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4525) Amastin PF07344.11 CBZ24109.1 - 4.9e-52 175.9 12.0 8.7e-52 175.1 12.0 1.4 1 0 0 1 1 1 1 Amastin surface glycoprotein Amastin PF07344.11 CBZ24110.1 - 3.3e-49 166.7 8.9 4e-49 166.4 8.9 1.1 1 0 0 1 1 1 1 Amastin surface glycoprotein DUF3087 PF11286.8 CBZ24110.1 - 3.7 7.0 4.5 0.83 9.1 0.5 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3087) DUF4407 PF14362.6 CBZ24110.1 - 4.1 6.7 5.8 6.6 6.0 5.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Amastin PF07344.11 CBZ24112.1 - 3.2e-32 111.5 14.8 3.8e-32 111.3 14.8 1.1 1 0 0 1 1 1 1 Amastin surface glycoprotein DUF3742 PF12553.8 CBZ24112.1 - 0.35 11.0 3.5 22 5.2 0.0 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF3742) Amastin PF07344.11 CBZ24113.1 - 6.1e-57 191.8 13.4 7.3e-57 191.6 13.4 1.0 1 0 0 1 1 1 1 Amastin surface glycoprotein SUR7 PF06687.12 CBZ24113.1 - 0.33 10.5 18.1 2.3 7.8 6.7 3.1 3 0 0 3 3 3 0 SUR7/PalI family Amastin PF07344.11 CBZ24114.1 - 3.5e-54 182.8 10.7 4.3e-54 182.6 10.7 1.1 1 0 0 1 1 1 1 Amastin surface glycoprotein DUF1772 PF08592.11 CBZ24114.1 - 0.55 10.5 4.6 8.6 6.7 2.0 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF1772) DUF2207 PF09972.9 CBZ24114.1 - 0.9 8.2 2.9 1 8.0 2.9 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) CotJB PF12652.7 CBZ24116.1 - 0.02 15.1 6.8 0.21 11.8 2.5 3.7 2 1 1 3 3 3 0 CotJB protein HCMV_UL139 PF12507.8 CBZ24116.1 - 0.052 13.9 0.7 2 8.8 2.5 2.3 1 1 1 2 2 2 0 Human Cytomegalovirus UL139 protein Terminase_4 PF05119.12 CBZ24116.1 - 0.075 13.5 0.3 0.36 11.3 0.3 2.2 2 0 0 2 2 2 0 Phage terminase, small subunit Adhesin_P1_N PF18652.1 CBZ24116.1 - 2.8 8.0 7.0 7.4 6.7 0.7 3.7 3 0 0 3 3 3 0 Adhesin P1 N-terminal domain SET PF00856.28 CBZ24117.1 - 7.8e-09 36.1 0.0 1.3e-07 32.1 0.0 2.8 1 1 0 1 1 1 1 SET domain SR-25 PF10500.9 CBZ24117.1 - 1.3 8.6 7.4 1.9 8.1 0.9 2.2 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein DNA_pol_B_thumb PF14791.6 CBZ24118.1 - 8.7e-21 73.9 0.0 1.8e-20 72.8 0.0 1.6 1 0 0 1 1 1 1 DNA polymerase beta thumb DNA_pol_B_palm PF14792.6 CBZ24118.1 - 5e-17 62.2 0.0 1.1e-16 61.1 0.0 1.6 1 0 0 1 1 1 1 DNA polymerase beta palm HHH_8 PF14716.6 CBZ24118.1 - 4.2e-14 52.7 0.2 2.1e-12 47.2 0.1 2.4 2 0 0 2 2 2 1 Helix-hairpin-helix domain DNA_pol_lambd_f PF10391.9 CBZ24118.1 - 1.2e-13 50.7 0.0 1.9e-12 46.8 0.0 2.7 3 0 0 3 3 3 1 Fingers domain of DNA polymerase lambda HHH_5 PF14520.6 CBZ24118.1 - 8.2e-05 23.1 0.1 0.0041 17.7 0.0 2.6 1 1 2 3 3 3 1 Helix-hairpin-helix domain HHH_3 PF12836.7 CBZ24118.1 - 0.05 13.9 0.1 8.1 6.8 0.0 2.7 2 0 0 2 2 2 0 Helix-hairpin-helix motif DMP12 PF16779.5 CBZ24118.1 - 0.06 13.3 0.0 0.099 12.6 0.0 1.3 1 0 0 1 1 1 0 DNA-mimic protein DNA_pol_B_palm PF14792.6 CBZ24119.1 - 1.5e-26 92.9 0.0 3.7e-26 91.6 0.0 1.7 1 0 0 1 1 1 1 DNA polymerase beta palm DNA_pol_B_thumb PF14791.6 CBZ24119.1 - 9.7e-17 60.9 0.1 3.1e-08 33.6 0.0 2.9 3 0 0 3 3 3 2 DNA polymerase beta thumb DNA_pol_lambd_f PF10391.9 CBZ24119.1 - 3.5e-09 36.3 0.1 3.1e-08 33.3 0.1 2.3 1 1 0 1 1 1 1 Fingers domain of DNA polymerase lambda HHH_5 PF14520.6 CBZ24119.1 - 0.00059 20.4 0.0 0.013 16.1 0.0 2.9 3 0 0 3 3 3 1 Helix-hairpin-helix domain HHH_8 PF14716.6 CBZ24119.1 - 0.0044 17.3 1.2 17 5.9 0.0 4.0 4 0 0 4 4 4 1 Helix-hairpin-helix domain NTP_transf_2 PF01909.23 CBZ24119.1 - 0.0047 17.2 0.0 0.014 15.6 0.0 1.8 1 0 0 1 1 1 1 Nucleotidyltransferase domain DXP_synthase_N PF13292.6 CBZ24119.1 - 0.14 11.4 0.0 0.24 10.6 0.0 1.3 1 0 0 1 1 1 0 1-deoxy-D-xylulose-5-phosphate synthase Lactamase_B_4 PF13691.6 CBZ24120.1 - 1.7e-05 24.4 0.3 5e-05 22.9 0.1 1.9 2 0 0 2 2 2 1 tRNase Z endonuclease Lactamase_B_2 PF12706.7 CBZ24120.1 - 0.017 14.7 5.3 0.022 14.3 0.2 2.7 2 0 0 2 2 2 0 Beta-lactamase superfamily domain Lactamase_B PF00753.27 CBZ24120.1 - 0.018 15.0 0.1 0.06 13.4 0.1 1.9 1 0 0 1 1 1 0 Metallo-beta-lactamase superfamily Pkinase PF00069.25 CBZ24122.1 - 3.1e-62 210.3 0.0 4.3e-61 206.6 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ24122.1 - 3.6e-45 154.3 0.0 5.4e-45 153.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CBZ24122.1 - 6.1e-06 25.8 0.0 1.2e-05 24.8 0.0 1.4 2 0 0 2 2 2 1 Kinase-like PKS_DE PF18369.1 CBZ24122.1 - 0.8 10.3 7.8 0.075 13.6 1.9 2.3 2 0 0 2 2 2 0 Polyketide synthase dimerisation element domain HTH_37 PF13744.6 CBZ24124.1 - 0.027 14.4 0.7 0.027 14.4 0.7 1.7 2 0 0 2 2 2 0 Helix-turn-helix domain Dpy-30 PF05186.13 CBZ24125.1 - 1.5e-06 27.8 0.1 3.2e-06 26.7 0.1 1.6 1 0 0 1 1 1 1 Dpy-30 motif MOFRL PF05161.13 CBZ24125.1 - 0.1 12.8 3.0 0.21 11.8 0.6 2.7 2 0 0 2 2 2 0 MOFRL family TMEM65 PF10507.9 CBZ24126.1 - 2.1e-30 104.9 1.2 7.3e-30 103.1 1.2 2.0 1 0 0 1 1 1 1 Transmembrane protein 65 DUF2057 PF09829.9 CBZ24127.1 - 6.7 6.8 6.5 0.69 10.0 0.4 2.5 2 1 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2057) DnaJ PF00226.31 CBZ24128.1 - 5.6e-17 61.6 0.5 5.3e-07 29.7 0.0 2.7 2 0 0 2 2 2 2 DnaJ domain DUF5401 PF17380.2 CBZ24128.1 - 0.97 7.4 12.8 1.4 6.9 12.8 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5401) AAA_5 PF07728.14 CBZ24129.1 - 3.7e-81 269.9 0.0 2e-31 108.8 0.0 3.6 3 0 0 3 3 3 3 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 CBZ24129.1 - 5.1e-08 33.5 1.2 0.004 17.5 0.0 4.6 4 0 0 4 4 3 2 AAA ATPase domain AAA PF00004.29 CBZ24129.1 - 6.9e-06 26.5 0.0 0.026 15.0 0.0 2.9 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 CBZ24129.1 - 1.6e-05 24.5 0.2 0.013 15.0 0.1 2.5 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA_22 PF13401.6 CBZ24129.1 - 5.6e-05 23.4 0.5 0.036 14.3 0.1 3.7 3 1 0 3 3 3 1 AAA domain TsaE PF02367.17 CBZ24129.1 - 9.2e-05 22.4 0.1 0.037 14.0 0.1 2.5 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_3 PF07726.11 CBZ24129.1 - 0.00019 21.3 0.0 0.093 12.6 0.0 2.7 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) IstB_IS21 PF01695.17 CBZ24129.1 - 0.00052 19.8 0.1 0.21 11.3 0.0 3.3 3 0 0 3 3 3 1 IstB-like ATP binding protein AAA_29 PF13555.6 CBZ24129.1 - 0.00064 19.4 0.0 0.74 9.6 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_14 PF13173.6 CBZ24129.1 - 0.0016 18.5 0.0 0.41 10.7 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_2 PF07724.14 CBZ24129.1 - 0.0018 18.4 0.0 2.5 8.2 0.0 2.6 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_18 PF13238.6 CBZ24129.1 - 0.0025 18.3 0.0 0.18 12.4 0.0 2.7 2 0 0 2 2 2 1 AAA domain Viral_helicase1 PF01443.18 CBZ24129.1 - 0.0033 17.2 0.0 0.047 13.4 0.0 2.3 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase Rad17 PF03215.15 CBZ24129.1 - 0.0076 16.2 0.0 0.053 13.4 0.0 2.2 2 0 0 2 2 2 1 Rad17 P-loop domain Sigma54_activat PF00158.26 CBZ24129.1 - 0.008 15.9 0.1 6.1 6.5 0.0 3.3 3 0 0 3 3 3 1 Sigma-54 interaction domain TniB PF05621.11 CBZ24129.1 - 0.0085 15.5 0.0 2.3 7.6 0.0 2.6 2 0 0 2 2 2 1 Bacterial TniB protein AAA_19 PF13245.6 CBZ24129.1 - 0.0089 16.4 0.7 4.1 7.7 0.0 3.3 2 1 0 2 2 2 1 AAA domain DUF815 PF05673.13 CBZ24129.1 - 0.021 14.0 0.1 2.5 7.2 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF815) DUF615 PF04751.14 CBZ24129.1 - 0.021 14.8 1.7 0.062 13.3 1.7 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF615) Mg_chelatase PF01078.21 CBZ24129.1 - 0.025 13.9 1.9 0.87 8.9 0.1 3.5 4 0 0 4 4 4 0 Magnesium chelatase, subunit ChlI VWA_2 PF13519.6 CBZ24129.1 - 0.027 15.1 0.0 0.12 13.0 0.0 2.2 1 0 0 1 1 1 0 von Willebrand factor type A domain ABC_tran PF00005.27 CBZ24129.1 - 0.029 14.9 0.0 0.55 10.7 0.0 2.8 2 0 0 2 2 2 0 ABC transporter AAA_33 PF13671.6 CBZ24129.1 - 0.037 14.2 0.4 1.4 9.1 0.0 3.4 4 0 0 4 4 3 0 AAA domain RuvB_N PF05496.12 CBZ24129.1 - 0.064 13.0 0.1 1.5 8.5 0.0 2.5 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain VWA PF00092.28 CBZ24129.1 - 0.084 13.1 0.0 0.34 11.2 0.0 1.9 2 0 0 2 2 2 0 von Willebrand factor type A domain RNA_helicase PF00910.22 CBZ24129.1 - 0.13 12.7 0.0 1.1 9.7 0.0 2.3 2 0 0 2 2 2 0 RNA helicase SMC_N PF02463.19 CBZ24129.1 - 0.14 11.6 0.0 2.4 7.5 0.0 2.2 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain Roc PF08477.13 CBZ24129.1 - 0.17 12.1 0.0 33 4.7 0.0 2.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Peptidase_C1 PF00112.23 CBZ24130.1 - 7.9e-71 238.6 1.0 1e-70 238.2 1.0 1.1 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.12 CBZ24130.1 - 8.8e-12 45.3 0.9 1.4e-11 44.6 0.9 1.3 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.15 CBZ24130.1 - 3.8e-06 25.9 0.2 0.00057 18.8 0.1 2.1 2 0 0 2 2 2 2 Peptidase C1-like family Peptidase_C1 PF00112.23 CBZ24131.1 - 4.1e-71 239.5 0.7 4.1e-71 239.5 0.7 1.9 2 0 0 2 2 2 1 Papain family cysteine protease DUF3586 PF12131.8 CBZ24131.1 - 5.3e-21 74.6 7.4 1.2e-20 73.5 7.4 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3586) Inhibitor_I29 PF08246.12 CBZ24131.1 - 1.1e-11 45.0 0.9 1.9e-11 44.2 0.9 1.4 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.15 CBZ24131.1 - 6.4e-06 25.2 0.2 0.00075 18.4 0.1 2.1 2 0 0 2 2 2 2 Peptidase C1-like family Peptidase_C1 PF00112.23 CBZ24132.1 - 5.2e-71 239.2 0.9 6.8e-71 238.8 0.9 1.1 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.12 CBZ24132.1 - 8.7e-12 45.3 0.9 1.4e-11 44.7 0.9 1.3 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.15 CBZ24132.1 - 8.7e-07 28.1 0.3 5.7e-05 22.1 0.1 2.1 2 0 0 2 2 2 2 Peptidase C1-like family Hist_deacetyl PF00850.19 CBZ24133.1 - 9.4e-60 202.7 0.0 1.7e-59 201.9 0.0 1.4 1 1 0 1 1 1 1 Histone deacetylase domain zf-RING_2 PF13639.6 CBZ24134.1 - 9.1e-08 32.3 5.3 9.1e-08 32.3 5.3 4.4 4 0 0 4 4 4 2 Ring finger domain zf-RING_5 PF14634.6 CBZ24134.1 - 0.00087 19.2 3.4 0.00087 19.2 3.4 4.9 4 2 1 5 5 5 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 CBZ24134.1 - 0.0055 16.5 5.9 0.0055 16.5 5.9 5.1 4 1 0 4 4 4 2 Zinc finger, C3HC4 type (RING finger) TPR_1 PF00515.28 CBZ24136.1 - 5.3e-52 171.6 34.8 5e-08 32.4 0.0 9.5 9 0 0 9 9 9 9 Tetratricopeptide repeat TPR_2 PF07719.17 CBZ24136.1 - 6.4e-44 144.5 29.7 1.7e-05 24.6 0.1 9.6 9 0 0 9 9 9 9 Tetratricopeptide repeat TPR_11 PF13414.6 CBZ24136.1 - 1.1e-28 98.6 31.5 7.7e-07 28.7 0.3 9.1 5 3 4 9 9 9 6 TPR repeat STI1 PF17830.1 CBZ24136.1 - 3.3e-28 97.4 4.5 1.7e-14 53.5 1.2 3.5 3 0 0 3 3 3 2 STI1 domain TPR_8 PF13181.6 CBZ24136.1 - 1.7e-22 77.7 26.5 0.00047 20.2 0.0 8.9 9 0 0 9 9 8 4 Tetratricopeptide repeat TPR_12 PF13424.6 CBZ24136.1 - 1.7e-19 69.9 21.8 2.6e-07 30.8 0.2 7.4 5 2 2 7 7 7 4 Tetratricopeptide repeat TPR_16 PF13432.6 CBZ24136.1 - 3.3e-17 62.8 10.4 0.00031 21.3 0.1 6.7 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_19 PF14559.6 CBZ24136.1 - 1.8e-16 60.4 9.0 0.076 13.5 0.0 6.8 5 1 1 6 6 6 5 Tetratricopeptide repeat TPR_14 PF13428.6 CBZ24136.1 - 1.1e-15 56.9 7.4 0.19 12.6 0.0 9.3 5 3 5 10 10 8 2 Tetratricopeptide repeat TPR_17 PF13431.6 CBZ24136.1 - 4.5e-12 45.5 14.0 0.25 11.8 0.3 7.8 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_9 PF13371.6 CBZ24136.1 - 2.6e-10 40.3 0.2 0.00028 21.0 0.0 4.6 5 1 1 6 6 4 2 Tetratricopeptide repeat TPR_7 PF13176.6 CBZ24136.1 - 1.6e-09 37.1 11.7 0.24 11.5 0.0 8.8 8 1 1 9 9 8 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 CBZ24136.1 - 7.5e-08 32.3 2.8 1.2 9.3 0.0 6.1 7 0 0 7 7 6 2 Fis1 C-terminal tetratricopeptide repeat TPR_10 PF13374.6 CBZ24136.1 - 2.8e-07 30.2 24.9 0.015 15.1 0.0 9.3 11 0 0 11 11 9 1 Tetratricopeptide repeat ANAPC3 PF12895.7 CBZ24136.1 - 6.1e-06 26.4 25.4 0.085 13.1 2.1 6.1 4 2 2 6 6 6 4 Anaphase-promoting complex, cyclosome, subunit 3 MIT PF04212.18 CBZ24136.1 - 0.00026 21.0 23.7 0.83 9.8 0.8 7.8 7 1 1 8 8 8 2 MIT (microtubule interacting and transport) domain TPR_6 PF13174.6 CBZ24136.1 - 0.00046 20.6 20.9 17 6.3 0.1 9.1 9 0 0 9 9 9 0 Tetratricopeptide repeat TPR_20 PF14561.6 CBZ24136.1 - 0.00046 20.5 0.1 1.9 8.9 0.0 4.3 3 0 0 3 3 3 1 Tetratricopeptide repeat SHNi-TPR PF10516.9 CBZ24136.1 - 0.00063 19.1 9.1 1.1 8.8 0.0 6.0 7 0 0 7 7 7 1 SHNi-TPR DHR-2 PF06920.13 CBZ24136.1 - 0.0091 14.7 0.7 0.021 13.5 0.7 1.6 1 0 0 1 1 1 1 Dock homology region 2 TPM_phosphatase PF04536.14 CBZ24136.1 - 0.028 14.6 1.8 3.2 7.9 0.1 3.8 3 0 0 3 3 3 0 TPM domain SRP_TPR_like PF17004.5 CBZ24136.1 - 0.028 14.4 14.3 0.18 11.9 0.2 4.7 3 2 1 4 4 4 0 Putative TPR-like repeat DUF3856 PF12968.7 CBZ24136.1 - 0.033 14.3 8.2 5.6 7.0 0.2 5.3 3 3 0 4 4 4 0 Domain of Unknown Function (DUF3856) DUF3808 PF10300.9 CBZ24136.1 - 0.034 12.9 2.2 0.1 11.3 0.1 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF3808) TPR_3 PF07720.12 CBZ24136.1 - 0.051 13.6 23.9 3 7.9 0.1 7.0 7 0 0 7 7 7 0 Tetratricopeptide repeat DnaI_N PF07319.11 CBZ24136.1 - 0.07 13.8 2.8 1.9 9.2 0.1 3.8 3 1 1 4 4 4 0 Primosomal protein DnaI N-terminus BTAD PF03704.17 CBZ24136.1 - 0.091 13.2 6.4 1.7 9.1 0.2 4.5 3 2 2 5 5 5 0 Bacterial transcriptional activator domain DUF4570 PF15134.6 CBZ24136.1 - 0.39 10.7 5.2 4.3 7.4 0.5 3.6 4 0 0 4 4 4 0 Domain of unknown function (DUF4570) RPN7 PF10602.9 CBZ24136.1 - 1.5 8.5 8.8 2.5 7.8 3.0 3.5 1 1 1 2 2 2 0 26S proteasome subunit RPN7 DUF1126 PF06565.12 CBZ24137.1 - 1.2e-61 205.0 0.0 2.3e-25 88.4 0.0 3.3 3 0 0 3 3 3 3 DUF1126 PH-like domain EF-hand_1 PF00036.32 CBZ24137.1 - 0.0036 16.8 0.0 0.017 14.6 0.0 2.2 2 0 0 2 2 2 1 EF hand EF-hand_5 PF13202.6 CBZ24137.1 - 0.017 14.6 0.0 0.043 13.3 0.0 1.7 1 0 0 1 1 1 0 EF hand EF-hand_6 PF13405.6 CBZ24137.1 - 0.058 13.4 0.0 0.77 9.8 0.0 2.8 3 0 0 3 3 3 0 EF-hand domain Pribosyltran_N PF13793.6 CBZ24138.1 - 1.7e-34 118.3 0.0 3.3e-34 117.3 0.0 1.5 1 0 0 1 1 1 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.6 CBZ24138.1 - 3.6e-24 85.8 0.3 1.4e-23 83.8 0.1 1.8 1 1 1 2 2 2 1 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.27 CBZ24138.1 - 6.3e-19 68.0 0.1 1.1e-18 67.2 0.1 1.3 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.6 CBZ24138.1 - 0.0035 16.8 0.1 0.0062 16.0 0.1 1.4 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Granulin PF00396.18 CBZ24139.1 - 0.22 11.9 2.5 0.69 10.3 2.5 1.8 1 0 0 1 1 1 0 Granulin Sec3_C PF09763.9 CBZ24140.1 - 3.6e-77 260.4 1.0 8.3e-38 130.2 0.3 2.1 2 0 0 2 2 2 2 Exocyst complex component Sec3 DUF812 PF05667.11 CBZ24140.1 - 0.00038 19.5 4.2 0.00067 18.7 4.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF812) Vps54_N PF10475.9 CBZ24140.1 - 0.016 14.5 4.4 0.035 13.4 4.4 1.5 1 0 0 1 1 1 0 Vacuolar-sorting protein 54, of GARP complex BRE1 PF08647.11 CBZ24140.1 - 0.07 13.2 3.0 0.22 11.6 3.0 1.9 1 0 0 1 1 1 0 BRE1 E3 ubiquitin ligase Exonuc_VII_L PF02601.15 CBZ24140.1 - 1.2 8.7 8.6 0.66 9.5 4.8 2.2 2 0 0 2 2 2 0 Exonuclease VII, large subunit TPMT PF05724.11 CBZ24141.1 - 5.5e-16 58.9 0.0 1.2e-15 57.8 0.0 1.5 1 0 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) Methyltransf_23 PF13489.6 CBZ24141.1 - 0.0013 18.6 0.0 0.0021 17.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CBZ24141.1 - 0.029 15.1 0.0 0.048 14.4 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain mTERF PF02536.14 CBZ24142.1 - 4.6e-05 22.5 0.0 0.00081 18.4 0.0 2.1 1 1 1 2 2 2 2 mTERF Slu7 PF11708.8 CBZ24143.1 - 5.5e-05 23.1 6.2 0.0004 20.2 6.2 2.3 1 1 1 2 2 2 1 Pre-mRNA splicing Prp18-interacting factor zf-CCHC_3 PF13917.6 CBZ24143.1 - 0.0031 17.5 0.7 0.0097 15.9 0.7 1.8 1 0 0 1 1 1 1 Zinc knuckle ANAPC4_WD40 PF12894.7 CBZ24144.1 - 2.1e-11 43.9 0.7 4.7e-06 26.8 0.0 5.0 2 1 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Coatomer_WDAD PF04053.14 CBZ24144.1 - 4.1e-09 36.0 3.1 0.00081 18.5 0.1 4.2 5 0 0 5 5 5 2 Coatomer WD associated region TPR_7 PF13176.6 CBZ24144.1 - 0.00023 20.9 7.3 0.081 13.0 0.4 4.8 4 0 0 4 4 4 1 Tetratricopeptide repeat Clathrin PF00637.20 CBZ24144.1 - 0.006 16.5 5.8 1.1 9.1 0.2 4.1 3 1 2 5 5 4 1 Region in Clathrin and VPS zf-RanBP PF00641.18 CBZ24144.1 - 0.01 15.1 10.7 0.013 14.8 2.8 2.7 2 0 0 2 2 2 0 Zn-finger in Ran binding protein and others WD40 PF00400.32 CBZ24144.1 - 0.015 16.2 13.7 1.3 10.0 0.0 6.3 7 0 0 7 7 6 0 WD domain, G-beta repeat eIF2A PF08662.11 CBZ24144.1 - 0.031 14.2 0.0 0.69 9.8 0.0 2.6 2 1 0 2 2 2 0 Eukaryotic translation initiation factor eIF2A Vps39_1 PF10366.9 CBZ24144.1 - 0.059 13.6 0.3 0.21 11.9 0.3 1.9 1 0 0 1 1 1 0 Vacuolar sorting protein 39 domain 1 TPR_12 PF13424.6 CBZ24144.1 - 0.11 12.9 17.0 0.29 11.5 0.2 4.7 5 0 0 5 5 5 0 Tetratricopeptide repeat RPN7 PF10602.9 CBZ24144.1 - 0.28 10.9 2.3 3.7 7.2 0.1 3.0 2 1 1 3 3 3 0 26S proteasome subunit RPN7 TPR_6 PF13174.6 CBZ24144.1 - 1.3 9.9 3.7 12 6.8 0.2 3.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.17 CBZ24144.1 - 1.6 9.0 20.5 0.86 9.9 1.0 5.3 5 0 0 5 5 5 0 Tetratricopeptide repeat DZR PF12773.7 CBZ24144.1 - 7.5 6.7 13.6 2.6e+02 1.8 13.6 2.9 1 1 0 1 1 1 0 Double zinc ribbon TPR_16 PF13432.6 CBZ24144.1 - 7.6 7.3 15.2 18 6.1 1.0 4.9 5 1 1 6 6 6 0 Tetratricopeptide repeat TPR_1 PF00515.28 CBZ24144.1 - 8.2 6.4 13.1 1.1 9.2 0.4 4.3 5 0 0 5 5 4 0 Tetratricopeptide repeat MIX PF18529.1 CBZ24145.1 - 6.7e-97 321.3 1.1 7.7e-97 321.1 1.1 1.0 1 0 0 1 1 1 1 Mitochondrial membrane-anchored proteins zf-C3HC4 PF00097.25 CBZ24147.1 - 3.6e-09 36.4 8.3 3.6e-09 36.4 8.3 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CBZ24147.1 - 4.3e-09 36.3 3.3 4.3e-09 36.3 3.3 2.6 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 CBZ24147.1 - 6.8e-09 35.4 11.4 1.2e-08 34.7 3.0 2.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 CBZ24147.1 - 4.7e-08 33.1 7.4 1.5e-07 31.5 7.4 2.0 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 CBZ24147.1 - 1.4e-07 31.3 7.1 1.4e-07 31.3 7.1 2.0 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 CBZ24147.1 - 6.9e-07 29.0 7.5 6.9e-07 29.0 7.5 1.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CBZ24147.1 - 1.8e-06 28.1 8.5 4.5e-06 26.9 8.5 1.7 1 0 0 1 1 1 1 Ring finger domain Prok-RING_4 PF14447.6 CBZ24147.1 - 0.00066 19.5 6.0 0.0015 18.3 6.0 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-rbx1 PF12678.7 CBZ24147.1 - 0.0014 18.8 6.4 0.0053 17.0 6.4 2.0 1 1 0 1 1 1 1 RING-H2 zinc finger domain Croc_4 PF17691.1 CBZ24147.1 - 0.0083 16.2 0.8 0.023 14.7 0.8 1.7 1 0 0 1 1 1 1 Contingent replication of cDNA 4 zf-ANAPC11 PF12861.7 CBZ24147.1 - 0.045 13.8 2.7 0.1 12.6 2.7 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger U-box PF04564.15 CBZ24147.1 - 0.048 13.8 0.1 0.13 12.4 0.1 1.8 1 0 0 1 1 1 0 U-box domain zf-Nse PF11789.8 CBZ24147.1 - 0.28 11.0 6.1 0.63 9.9 6.1 1.6 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-RING_11 PF17123.5 CBZ24147.1 - 1.6 8.5 5.7 5.3 6.9 5.7 2.0 1 1 0 1 1 1 0 RING-like zinc finger Kinesin_assoc PF16183.5 CBZ24148.1 - 0.14 12.3 0.2 0.43 10.7 0.2 1.8 1 1 0 1 1 1 0 Kinesin-associated KduI PF04962.12 CBZ24149.1 - 0.0096 15.3 0.1 0.01 15.1 0.1 1.1 1 0 0 1 1 1 1 KduI/IolB family Glyco_hydr_116N PF12215.8 CBZ24149.1 - 0.024 14.1 0.5 0.025 14.0 0.5 1.0 1 0 0 1 1 1 0 beta-glucosidase 2, glycosyl-hydrolase family 116 N-term Amidinotransf PF02274.17 CBZ24151.1 - 1.1e-10 41.2 0.0 1.7e-10 40.6 0.0 1.2 1 0 0 1 1 1 1 Amidinotransferase Pkinase PF00069.25 CBZ24152.1 - 9e-48 162.9 0.0 5.6e-47 160.3 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ24152.1 - 1.3e-33 116.4 0.0 2.1e-33 115.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CBZ24152.1 - 4.2e-05 23.0 0.0 9.1e-05 21.9 0.0 1.5 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.22 CBZ24152.1 - 0.003 17.2 0.0 0.0066 16.1 0.0 1.5 1 0 0 1 1 1 1 RIO1 family Pkinase_fungal PF17667.1 CBZ24152.1 - 0.0075 15.1 0.0 0.012 14.4 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 CBZ24152.1 - 0.047 13.6 0.0 0.1 12.5 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family Tubulin PF00091.25 CBZ24153.1 - 5.4e-68 229.1 0.0 8.4e-68 228.5 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 CBZ24153.1 - 4.3e-42 143.2 0.0 6.4e-42 142.7 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 CBZ24153.1 - 7.6e-05 23.0 0.0 0.00016 22.0 0.0 1.5 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.6 CBZ24153.1 - 0.0052 16.5 0.0 0.009 15.7 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain Tubulin_2 PF13809.6 CBZ24153.1 - 0.053 12.7 0.1 0.18 10.9 0.0 1.7 2 0 0 2 2 2 0 Tubulin like Tubulin PF00091.25 CBZ24154.1 - 4e-68 229.5 0.0 6.5e-68 228.8 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 CBZ24154.1 - 1.6e-41 141.4 0.1 2.3e-41 140.9 0.1 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 CBZ24154.1 - 8.3e-05 22.9 0.0 0.00021 21.6 0.0 1.7 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.6 CBZ24154.1 - 0.0056 16.4 0.0 0.01 15.5 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain Tubulin_2 PF13809.6 CBZ24154.1 - 0.058 12.6 0.2 0.2 10.8 0.0 1.8 2 0 0 2 2 2 0 Tubulin like YliH PF10799.8 CBZ24155.1 - 0.016 15.1 0.4 0.023 14.6 0.2 1.3 1 1 0 1 1 1 0 Biofilm formation protein (YliH/bssR) SlyX PF04102.12 CBZ24155.1 - 0.025 15.2 4.4 2.8 8.6 0.5 2.3 2 0 0 2 2 2 0 SlyX DUF3138 PF11336.8 CBZ24155.1 - 0.028 13.1 1.2 0.032 12.9 1.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) Lzipper-MIP1 PF14389.6 CBZ24155.1 - 0.03 14.6 8.0 2.3 8.6 3.6 2.2 2 0 0 2 2 2 0 Leucine-zipper of ternary complex factor MIP1 DUF5082 PF16888.5 CBZ24155.1 - 0.059 13.6 2.5 6.4 7.1 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF5082) Rx_N PF18052.1 CBZ24155.1 - 0.31 11.3 3.0 0.51 10.7 1.2 1.9 2 0 0 2 2 2 0 Rx N-terminal domain DUF1192 PF06698.11 CBZ24155.1 - 0.57 10.3 6.8 6.1 7.0 1.5 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF1192) ANAPC4_WD40 PF12894.7 CBZ24156.1 - 0.00026 21.2 0.0 0.75 10.1 0.0 3.6 2 2 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 CBZ24156.1 - 0.19 11.0 0.0 8 5.7 0.0 2.3 2 0 0 2 2 2 0 WD40-like domain WD40 PF00400.32 CBZ24156.1 - 1.1 10.3 4.6 97 4.1 0.0 4.2 4 0 0 4 4 4 0 WD domain, G-beta repeat PEX11 PF05648.14 CBZ24159.1 - 2.2e-09 37.1 5.6 4.5e-07 29.6 5.6 2.4 1 1 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) PIG-L PF02585.17 CBZ24160.1 - 1.2e-22 81.0 0.0 1.5e-22 80.6 0.0 1.2 1 0 0 1 1 1 1 GlcNAc-PI de-N-acetylase HhH-GPD PF00730.25 CBZ24161.1 - 1.3e-20 73.9 0.0 1.9e-20 73.3 0.0 1.3 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.23 CBZ24161.1 - 3.6e-05 23.4 0.0 9.8e-05 22.0 0.0 1.8 1 0 0 1 1 1 1 Helix-hairpin-helix motif EndIII_4Fe-2S PF10576.9 CBZ24161.1 - 0.00074 19.8 4.0 0.0014 18.9 4.0 1.5 1 0 0 1 1 1 1 Iron-sulfur binding domain of endonuclease III Toxin_R_bind_C PF07951.12 CBZ24161.1 - 0.032 13.9 0.0 0.046 13.4 0.0 1.2 1 0 0 1 1 1 0 Clostridium neurotoxin, C-terminal receptor binding CRS1_YhbY PF01985.21 CBZ24161.1 - 0.1 12.8 0.3 0.14 12.3 0.0 1.6 2 0 0 2 2 2 0 CRS1 / YhbY (CRM) domain RRM_1 PF00076.22 CBZ24162.1 - 9.4e-21 73.4 0.0 1.2e-20 73.1 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CBZ24162.1 - 0.00014 21.9 0.1 0.0012 18.9 0.0 2.3 1 1 1 2 2 2 1 RNA recognition motif RNA_bind PF08675.11 CBZ24162.1 - 0.0062 16.5 0.0 0.013 15.5 0.0 1.7 1 1 1 2 2 2 1 RNA binding domain HA2 PF04408.23 CBZ24163.1 - 5.6e-19 68.4 0.0 2.6e-18 66.3 0.0 2.2 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 CBZ24163.1 - 5.8e-13 49.0 0.0 1.2e-12 48.0 0.0 1.5 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 CBZ24163.1 - 1.4e-12 47.9 0.0 3.9e-12 46.5 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 CBZ24163.1 - 1.9e-10 40.8 1.1 5.5e-10 39.3 0.1 2.2 3 0 0 3 3 3 1 DEAD/DEAH box helicase zf-CCHC PF00098.23 CBZ24163.1 - 9.6e-05 22.3 1.9 9.6e-05 22.3 1.9 2.7 2 0 0 2 2 2 1 Zinc knuckle T2SSE PF00437.20 CBZ24163.1 - 0.00011 21.4 0.0 0.00025 20.2 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_19 PF13245.6 CBZ24163.1 - 0.00034 21.0 0.1 0.0012 19.2 0.1 1.9 1 0 0 1 1 1 1 AAA domain RWD PF05773.22 CBZ24163.1 - 0.00087 19.6 0.0 0.0033 17.7 0.0 2.0 2 0 0 2 2 2 1 RWD domain AAA_22 PF13401.6 CBZ24163.1 - 0.0024 18.2 0.8 0.015 15.6 0.4 2.6 1 1 1 2 2 2 1 AAA domain AAA_30 PF13604.6 CBZ24163.1 - 0.025 14.3 0.1 0.072 12.8 0.1 1.7 1 0 0 1 1 1 0 AAA domain ATPase PF06745.13 CBZ24163.1 - 0.1 11.9 0.1 0.25 10.7 0.1 1.6 1 0 0 1 1 1 0 KaiC ABC_tran PF00005.27 CBZ24163.1 - 0.16 12.5 0.0 0.44 11.1 0.0 1.7 1 0 0 1 1 1 0 ABC transporter AAA_7 PF12775.7 CBZ24163.1 - 0.16 11.4 0.0 0.56 9.7 0.0 1.8 2 0 0 2 2 2 0 P-loop containing dynein motor region Sigma54_activat PF00158.26 CBZ24163.1 - 0.17 11.6 0.0 0.37 10.5 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain RRM_1 PF00076.22 CBZ24164.1 - 8.2e-19 67.2 0.0 1.4e-18 66.4 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CBZ24164.1 - 0.00089 19.3 0.0 0.0024 18.0 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif RRM_5 PF13893.6 CBZ24164.1 - 0.0015 18.1 0.0 0.0027 17.3 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.22 CBZ24165.1 - 4.5e-16 58.4 0.0 7.1e-16 57.8 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) BILBO1_N PF18281.1 CBZ24166.1 - 1e-31 109.2 0.1 4.3e-31 107.2 0.1 2.1 1 0 0 1 1 1 1 BILBO1 N-terminal domain EF-hand_7 PF13499.6 CBZ24166.1 - 1e-09 38.7 3.5 1e-09 38.7 3.5 2.9 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.32 CBZ24166.1 - 1.7e-05 24.0 4.1 0.0052 16.2 0.0 3.0 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.6 CBZ24166.1 - 0.00025 20.8 2.9 0.48 10.5 0.0 3.3 3 0 0 3 3 3 2 EF-hand domain EF-hand_8 PF13833.6 CBZ24166.1 - 0.00047 20.0 1.1 0.011 15.6 0.5 2.5 1 1 1 2 2 2 1 EF-hand domain pair EF-hand_5 PF13202.6 CBZ24166.1 - 0.0071 15.8 0.0 0.019 14.4 0.0 1.8 1 0 0 1 1 1 1 EF hand SPARC_Ca_bdg PF10591.9 CBZ24166.1 - 1.6 9.1 0.0 1.6 9.1 0.0 3.4 3 1 0 3 3 3 0 Secreted protein acidic and rich in cysteine Ca binding region DUF3584 PF12128.8 CBZ24166.1 - 2 5.8 64.9 0.11 10.0 32.3 2.7 1 1 2 3 3 3 0 Protein of unknown function (DUF3584) Phycobilisome PF00502.19 CBZ24167.1 - 0.013 15.4 1.1 0.03 14.3 0.6 1.8 2 0 0 2 2 2 0 Phycobilisome protein Kinesin PF00225.23 CBZ24169.1 - 1.9e-77 260.4 0.0 1.1e-45 156.0 0.0 2.8 2 1 0 2 2 2 2 Kinesin motor domain Microtub_bd PF16796.5 CBZ24169.1 - 1.2e-18 67.5 0.1 8.1e-18 64.8 0.0 2.5 2 1 0 2 2 2 1 Microtubule binding AAA_22 PF13401.6 CBZ24169.1 - 0.014 15.7 0.3 0.12 12.6 0.0 2.8 2 0 0 2 2 2 0 AAA domain DEAD PF00270.29 CBZ24169.1 - 0.019 14.7 0.3 0.12 12.1 0.0 2.3 2 0 0 2 2 2 0 DEAD/DEAH box helicase DUF87 PF01935.17 CBZ24169.1 - 0.15 12.1 0.0 0.15 12.1 0.0 2.9 3 0 0 3 3 3 0 Helicase HerA, central domain zf-CRD PF17979.1 CBZ24170.1 - 1.5e-43 148.7 0.5 1.5e-43 148.7 0.5 2.2 2 0 0 2 2 2 1 Cysteine rich domain with multizinc binding regions FHA PF00498.26 CBZ24170.1 - 1.2e-15 57.6 0.2 2.3e-15 56.7 0.2 1.5 1 0 0 1 1 1 1 FHA domain zf-C3HC4 PF00097.25 CBZ24170.1 - 3e-07 30.2 12.3 3e-07 30.2 12.3 2.8 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CBZ24170.1 - 3.4e-06 27.3 13.7 3.4e-06 27.3 13.7 3.3 3 0 0 3 3 2 1 Ring finger domain zf-C3HC4_2 PF13923.6 CBZ24170.1 - 6.5e-06 25.9 13.5 6.5e-06 25.9 13.5 3.2 3 1 1 4 4 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 CBZ24170.1 - 7.6e-06 26.0 13.0 7.6e-06 26.0 13.0 3.4 3 1 0 3 3 2 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.6 CBZ24170.1 - 1.3e-05 25.1 14.0 1.3e-05 25.1 14.0 2.9 4 0 0 4 4 2 1 RING-type zinc-finger FHA_2 PF17913.1 CBZ24170.1 - 1.9e-05 24.8 0.0 3.3e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 FHA domain zf-CCHH PF10283.9 CBZ24170.1 - 2.2e-05 24.3 8.7 5.4e-05 23.1 8.7 1.7 1 0 0 1 1 1 1 PBZ domain zf-RING_5 PF14634.6 CBZ24170.1 - 5.6e-05 23.0 10.4 5.6e-05 23.0 10.4 3.4 4 0 0 4 4 4 1 zinc-RING finger domain Yop-YscD_cpl PF16697.5 CBZ24170.1 - 0.0015 18.8 0.2 0.0028 18.0 0.2 1.4 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain zf-Nse PF11789.8 CBZ24170.1 - 0.0037 17.0 6.0 0.011 15.6 6.0 1.8 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_6 PF14835.6 CBZ24170.1 - 0.0058 16.5 6.4 0.0058 16.5 6.4 2.9 2 1 0 2 2 2 1 zf-RING of BARD1-type protein Atg8 PF02991.16 CBZ24171.1 - 5.8e-06 26.4 0.0 9.9e-06 25.7 0.0 1.4 1 1 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like Pox_Ag35 PF03286.14 CBZ24171.1 - 0.064 13.0 0.4 0.087 12.6 0.4 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Atg8 PF02991.16 CBZ24172.1 - 6.7e-05 23.0 0.0 0.00013 22.2 0.0 1.4 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like Pox_Ag35 PF03286.14 CBZ24172.1 - 0.33 10.7 0.4 0.53 10.0 0.4 1.3 1 0 0 1 1 1 0 Pox virus Ag35 surface protein TANGO2 PF05742.12 CBZ24174.1 - 2.1e-17 64.1 0.0 4.1e-13 50.0 0.0 3.1 2 1 0 2 2 2 2 Transport and Golgi organisation 2 DUF4586 PF15239.6 CBZ24175.1 - 2.6e-34 119.8 5.9 3.6e-34 119.3 5.9 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4586) VTC PF09359.10 CBZ24176.1 - 9e-77 258.2 0.2 1.3e-76 257.6 0.2 1.3 1 0 0 1 1 1 1 VTC domain DUF202 PF02656.15 CBZ24176.1 - 6.3e-06 26.6 0.5 6.3e-06 26.6 0.5 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF202) AAA_2 PF07724.14 CBZ24177.1 - 8.1e-42 143.2 0.2 1.7e-33 116.2 0.1 2.6 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA PF00004.29 CBZ24177.1 - 1.2e-12 48.4 0.5 8.9e-05 22.9 0.0 2.8 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.9 CBZ24177.1 - 1.9e-06 27.8 0.2 9.8e-06 25.5 0.0 2.3 2 0 0 2 2 2 1 C-terminal, D2-small domain, of ClpB protein AAA_5 PF07728.14 CBZ24177.1 - 4e-06 26.9 0.1 8.1e-05 22.6 0.0 2.8 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) MCM PF00493.23 CBZ24177.1 - 0.00011 21.4 0.1 0.014 14.5 0.0 2.4 2 0 0 2 2 2 1 MCM P-loop domain AAA_22 PF13401.6 CBZ24177.1 - 0.00014 22.1 0.1 0.0028 17.9 0.0 2.6 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.6 CBZ24177.1 - 0.0015 19.0 5.6 0.06 13.7 4.5 3.1 2 1 0 2 2 2 1 AAA ATPase domain ATP-synt_ab PF00006.25 CBZ24177.1 - 0.0059 16.3 0.2 0.011 15.5 0.2 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain AAA_18 PF13238.6 CBZ24177.1 - 0.01 16.4 0.1 0.16 12.5 0.0 2.7 2 2 0 2 2 2 0 AAA domain RuvB_N PF05496.12 CBZ24177.1 - 0.014 15.2 0.0 0.44 10.3 0.0 2.5 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain Sigma54_activat PF00158.26 CBZ24177.1 - 0.017 14.8 0.0 0.19 11.4 0.0 2.6 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_19 PF13245.6 CBZ24177.1 - 0.036 14.4 0.6 0.14 12.5 0.6 2.0 1 1 0 1 1 1 0 AAA domain AAA_7 PF12775.7 CBZ24177.1 - 0.04 13.4 0.0 0.28 10.7 0.0 2.1 2 0 0 2 2 2 0 P-loop containing dynein motor region Mg_chelatase PF01078.21 CBZ24177.1 - 0.045 13.1 2.8 0.056 12.8 0.0 2.6 4 0 0 4 4 4 0 Magnesium chelatase, subunit ChlI AAA_33 PF13671.6 CBZ24177.1 - 0.046 13.9 0.5 0.2 11.8 0.5 2.1 2 1 0 2 2 2 0 AAA domain DEAD PF00270.29 CBZ24177.1 - 0.056 13.2 0.1 11 5.7 0.0 2.7 3 0 0 3 3 3 0 DEAD/DEAH box helicase AAA_24 PF13479.6 CBZ24177.1 - 0.063 13.0 0.1 0.14 11.9 0.0 1.6 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.27 CBZ24177.1 - 0.087 13.3 0.0 0.59 10.6 0.0 2.3 2 0 0 2 2 2 0 ABC transporter AAA_8 PF12780.7 CBZ24177.1 - 0.11 11.8 0.0 0.46 9.8 0.0 1.9 2 0 0 2 2 2 0 P-loop containing dynein motor region D4 UCH PF00443.29 CBZ24178.1 - 3.1e-37 128.5 0.0 4.1e-37 128.1 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 CBZ24178.1 - 0.00011 21.9 0.2 0.00065 19.4 0.0 2.1 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase Lipid_DES PF08557.10 CBZ24178.1 - 0.18 11.3 0.1 0.43 10.1 0.1 1.6 1 0 0 1 1 1 0 Sphingolipid Delta4-desaturase (DES) MCM PF00493.23 CBZ24179.1 - 5.9e-90 300.3 0.0 3.4e-89 297.8 0.0 2.0 1 1 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 CBZ24179.1 - 5.2e-35 120.0 0.9 1e-34 119.1 0.9 1.5 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 CBZ24179.1 - 5.5e-24 84.4 3.5 1.1e-23 83.5 3.5 1.5 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 CBZ24179.1 - 3.9e-09 37.0 0.0 1.3e-08 35.3 0.0 1.9 2 0 0 2 2 2 1 MCM N-terminal domain AAA_5 PF07728.14 CBZ24179.1 - 5.1e-09 36.2 0.0 1.1e-08 35.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 CBZ24179.1 - 6.2e-08 32.3 0.0 1.2e-05 24.8 0.0 2.7 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_16 PF13191.6 CBZ24179.1 - 0.0013 19.2 0.2 0.047 14.1 0.0 3.0 2 1 1 3 3 3 1 AAA ATPase domain Sigma54_activat PF00158.26 CBZ24179.1 - 0.0014 18.4 0.0 0.055 13.2 0.0 2.7 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_3 PF07726.11 CBZ24179.1 - 0.0021 17.9 0.0 0.0052 16.6 0.0 1.7 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) NTPase_1 PF03266.15 CBZ24179.1 - 0.083 12.8 0.1 18 5.2 0.0 2.5 1 1 1 2 2 2 0 NTPase G10 PF01125.17 CBZ24180.1 - 7e-49 165.4 0.6 4.2e-48 162.8 0.6 1.9 1 1 0 1 1 1 1 G10 protein MFS_1 PF07690.16 CBZ24181.1 - 1.3e-23 83.6 35.0 1.7e-18 66.7 14.1 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 CBZ24181.1 - 0.0013 17.6 6.3 0.0013 17.6 6.3 1.6 2 0 0 2 2 2 1 MFS_1 like family Kinesin PF00225.23 CBZ24183.1 - 6.7e-32 110.7 0.1 7.4e-11 41.6 0.0 3.9 3 1 0 3 3 3 3 Kinesin motor domain Microtub_bd PF16796.5 CBZ24183.1 - 0.23 11.4 0.1 0.78 9.7 0.0 1.9 2 0 0 2 2 2 0 Microtubule binding Pkinase PF00069.25 CBZ24185.1 - 1.8e-48 165.2 0.0 1e-47 162.7 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ24185.1 - 1.5e-19 70.3 0.2 1.4e-18 67.2 0.0 2.3 2 1 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 CBZ24185.1 - 0.00035 20.0 0.0 0.0006 19.2 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 CBZ24185.1 - 0.00036 20.5 0.0 0.00036 20.5 0.0 2.2 2 1 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 CBZ24185.1 - 0.022 14.1 0.1 0.042 13.2 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 CBZ24185.1 - 0.028 13.2 0.0 0.047 12.5 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase Haspin_kinase PF12330.8 CBZ24185.1 - 0.044 12.7 0.0 0.07 12.1 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain RIO1 PF01163.22 CBZ24185.1 - 0.081 12.5 0.1 0.69 9.5 0.0 2.1 2 0 0 2 2 2 0 RIO1 family CHASE PF03924.13 CBZ24186.1 - 0.089 12.7 0.0 0.18 11.7 0.0 1.4 1 0 0 1 1 1 0 CHASE domain CHASE PF03924.13 CBZ24187.1 - 0.016 15.2 0.0 0.033 14.1 0.0 1.5 1 0 0 1 1 1 0 CHASE domain DUF3040 PF11239.8 CBZ24187.1 - 0.85 9.9 3.3 4.9 7.5 0.2 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3040) EphA2_TM PF14575.6 CBZ24188.1 - 0.15 13.0 1.0 20 6.1 0.1 2.6 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain zf-RING_2 PF13639.6 CBZ24190.1 - 1.9e-08 34.5 10.6 2e-08 34.4 7.2 2.3 2 0 0 2 2 2 1 Ring finger domain zf-rbx1 PF12678.7 CBZ24190.1 - 2.7e-08 33.9 2.0 2.7e-08 33.9 2.0 2.0 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 CBZ24190.1 - 9.9e-05 22.1 8.9 9.9e-05 22.1 8.9 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 CBZ24190.1 - 9.9e-05 22.0 4.9 0.0003 20.4 1.1 2.4 2 0 0 2 2 2 1 RING-like zinc finger zf-C3HC4 PF00097.25 CBZ24190.1 - 0.00036 20.3 2.8 0.00036 20.3 2.8 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 CBZ24190.1 - 0.00065 19.7 1.8 0.0018 18.3 1.8 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.6 CBZ24190.1 - 0.0017 18.2 6.3 0.0017 18.2 6.3 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 CBZ24190.1 - 0.0045 16.8 4.9 0.013 15.4 4.9 1.8 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 CBZ24190.1 - 0.0085 16.1 4.1 0.0085 16.1 4.1 2.1 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_5 PF14634.6 CBZ24190.1 - 0.076 13.0 9.5 0.02 14.9 5.9 1.9 2 0 0 2 2 2 0 zinc-RING finger domain Zn_ribbon_17 PF17120.5 CBZ24190.1 - 1.2 8.9 9.5 0.14 11.8 4.9 1.9 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type zf-C3HC4_4 PF15227.6 CBZ24190.1 - 1.7 8.9 9.6 0.39 10.9 5.4 2.0 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-C3H2C3 PF17122.5 CBZ24190.1 - 3.1 7.9 6.6 7.1 6.8 6.6 1.6 1 0 0 1 1 1 0 Zinc-finger FAD_binding_7 PF03441.14 CBZ24191.1 - 3.1e-34 118.2 0.2 5.3e-34 117.5 0.2 1.3 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.18 CBZ24191.1 - 2.2e-19 70.1 0.7 9.6e-19 68.0 0.3 2.3 2 0 0 2 2 2 1 DNA photolyase Ank_4 PF13637.6 CBZ24192.1 - 5.1e-08 33.3 0.3 2.1e-07 31.3 0.0 2.1 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 CBZ24192.1 - 9.6e-05 22.5 0.1 0.0017 18.7 0.0 2.6 2 0 0 2 2 2 1 Ankyrin repeat Ank_2 PF12796.7 CBZ24192.1 - 9.9e-05 22.9 0.0 0.00025 21.6 0.0 1.8 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 CBZ24192.1 - 0.0052 17.1 0.1 0.021 15.1 0.0 2.0 1 1 1 2 2 2 2 Ankyrin repeats (many copies) CX9C PF16860.5 CBZ24193.1 - 1.5e-05 24.9 1.5 2.8e-05 24.0 1.5 1.4 1 0 0 1 1 1 1 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, CHCH PF06747.13 CBZ24193.1 - 0.023 14.8 1.7 3.2 8.0 0.1 2.2 2 0 0 2 2 2 0 CHCH domain Cmc1 PF08583.10 CBZ24193.1 - 0.039 14.0 2.2 0.16 12.0 2.0 1.9 1 1 0 1 1 1 0 Cytochrome c oxidase biogenesis protein Cmc1 like UPF0203 PF05254.12 CBZ24193.1 - 0.045 14.0 1.9 1.4 9.2 1.9 2.1 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0203) UCR_hinge PF02320.16 CBZ24193.1 - 0.23 11.7 2.4 0.46 10.7 2.4 1.5 1 1 0 1 1 1 0 Ubiquinol-cytochrome C reductase hinge protein NDUF_B7 PF05676.13 CBZ24193.1 - 2 8.2 6.6 6.2 6.6 0.9 2.6 1 1 2 3 3 3 0 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) Het-C PF07217.11 CBZ24195.1 - 0.073 11.6 0.2 0.1 11.1 0.2 1.2 1 0 0 1 1 1 0 Heterokaryon incompatibility protein Het-C FAM76 PF16046.5 CBZ24195.1 - 0.49 9.7 5.9 0.8 9.0 5.9 1.4 1 1 0 1 1 1 0 FAM76 protein FlxA PF14282.6 CBZ24195.1 - 2.5 8.2 17.5 3.8 7.6 10.6 2.6 2 0 0 2 2 2 0 FlxA-like protein DUF755 PF05501.11 CBZ24195.1 - 2.7 8.3 8.2 4.1 7.7 4.8 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF755) Pkinase PF00069.25 CBZ24197.1 - 2e-41 142.1 0.0 2.6e-41 141.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ24197.1 - 6.5e-17 61.7 0.0 9.2e-17 61.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 CBZ24197.1 - 0.019 14.9 0.4 2 8.3 0.0 2.4 2 0 0 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.14 CBZ24197.1 - 0.027 13.8 0.1 0.048 13.0 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 CBZ24197.1 - 0.2 10.5 0.0 0.24 10.3 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain DSPn PF14671.6 CBZ24198.1 - 3.4e-19 69.7 0.0 2.6e-12 47.4 0.0 2.3 2 0 0 2 2 2 2 Dual specificity protein phosphatase, N-terminal half DSPc PF00782.20 CBZ24198.1 - 4e-08 33.1 0.1 7.6e-08 32.2 0.1 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 CBZ24198.1 - 0.0015 18.1 0.1 0.0026 17.4 0.1 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Plus-3 PF03126.18 CBZ24199.1 - 1.9e-14 54.1 0.0 6.5e-14 52.4 0.0 1.9 2 0 0 2 2 2 1 Plus-3 domain zf-C3HC4_3 PF13920.6 CBZ24199.1 - 1.1e-09 37.9 15.1 1.8e-09 37.3 15.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 CBZ24199.1 - 0.013 15.3 14.4 0.024 14.5 14.4 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 TFIIA PF03153.13 CBZ24199.1 - 0.033 14.2 4.8 0.044 13.8 4.8 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit TPR_1 PF00515.28 CBZ24200.1 - 2.3e-15 55.6 16.9 0.0026 17.5 0.0 9.0 9 0 0 9 9 9 4 Tetratricopeptide repeat TPR_8 PF13181.6 CBZ24200.1 - 8.3e-14 50.6 2.7 0.072 13.3 0.0 7.0 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_2 PF07719.17 CBZ24200.1 - 3.6e-13 48.5 17.5 0.064 13.4 0.0 8.4 9 0 0 9 9 9 4 Tetratricopeptide repeat TPR_14 PF13428.6 CBZ24200.1 - 4.7e-12 45.6 14.1 0.064 14.1 0.6 6.8 5 1 2 7 7 6 4 Tetratricopeptide repeat TPR_16 PF13432.6 CBZ24200.1 - 1.3e-10 41.7 13.5 0.06 14.0 0.7 6.8 4 1 3 7 7 7 4 Tetratricopeptide repeat TPR_12 PF13424.6 CBZ24200.1 - 1.6e-09 37.9 13.1 0.1 12.9 0.1 6.4 4 1 3 7 7 7 2 Tetratricopeptide repeat TPR_9 PF13371.6 CBZ24200.1 - 8e-09 35.5 10.9 0.0075 16.4 0.3 4.7 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_19 PF14559.6 CBZ24200.1 - 5e-06 26.9 15.4 0.076 13.5 1.5 5.4 3 2 3 6 6 6 2 Tetratricopeptide repeat TPR_6 PF13174.6 CBZ24200.1 - 0.0022 18.5 8.3 5.7 7.8 0.0 5.1 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_11 PF13414.6 CBZ24200.1 - 0.0036 16.9 7.7 12 5.7 0.1 6.0 5 2 2 7 7 7 1 TPR repeat TPR_17 PF13431.6 CBZ24200.1 - 0.022 15.1 8.7 15 6.2 0.0 7.2 10 0 0 10 10 7 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 CBZ24200.1 - 0.089 12.9 12.0 0.48 10.5 0.0 4.8 6 0 0 6 6 6 0 Fis1 C-terminal tetratricopeptide repeat TPR_7 PF13176.6 CBZ24200.1 - 0.5 10.5 8.3 59 4.0 0.2 5.7 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_10 PF13374.6 CBZ24200.1 - 2.7 8.0 13.9 36 4.4 2.3 4.9 5 0 0 5 5 5 0 Tetratricopeptide repeat Mon2_C PF16206.5 CBZ24202.1 - 3.2e-09 35.5 0.0 7.8e-09 34.3 0.0 1.6 1 0 0 1 1 1 1 C-terminal region of Mon2 protein DUF1981 PF09324.10 CBZ24202.1 - 0.046 13.6 0.2 18 5.3 0.0 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF1981) HEAT PF02985.22 CBZ24202.1 - 0.11 12.8 0.6 7.5 7.1 0.0 3.8 2 0 0 2 2 2 0 HEAT repeat Metallophos PF00149.28 CBZ24203.1 - 4.3e-22 79.6 0.5 6.2e-22 79.1 0.5 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase IRK_C PF17655.1 CBZ24204.1 - 7.3e-06 25.7 0.0 0.014 15.0 0.0 2.4 2 0 0 2 2 2 2 Inward rectifier potassium channel C-terminal domain Acyltransferase PF01553.21 CBZ24205.1 - 0.0048 16.5 0.0 0.028 14.0 0.0 2.1 1 1 0 1 1 1 1 Acyltransferase LRR_4 PF12799.7 CBZ24209.1 - 0.0016 18.8 8.1 4.7 7.8 0.0 5.5 4 2 2 6 6 6 3 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 CBZ24209.1 - 0.058 12.9 0.1 0.18 11.3 0.1 1.8 1 0 0 1 1 1 0 Leucine-rich repeat LRR_8 PF13855.6 CBZ24209.1 - 0.092 12.5 6.4 1.7 8.5 0.0 4.4 4 1 1 5 5 5 0 Leucine rich repeat LRR_6 PF13516.6 CBZ24209.1 - 0.12 12.5 5.6 4.3 7.6 0.0 5.2 6 0 0 6 6 6 0 Leucine Rich repeat Med9 PF07544.13 CBZ24209.1 - 0.42 10.7 1.6 0.91 9.7 1.6 1.5 1 0 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 Cep57_CLD_2 PF14197.6 CBZ24209.1 - 4.3 7.5 9.6 1.3 9.2 0.2 3.0 2 1 0 2 2 2 0 Centrosome localisation domain of PPC89 DSPc PF00782.20 CBZ24211.1 - 1.1e-07 31.7 0.1 5.7e-06 26.2 0.0 2.5 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 CBZ24211.1 - 0.23 11.0 0.0 0.41 10.2 0.0 1.3 1 0 0 1 1 1 0 Protein-tyrosine phosphatase His_Phos_1 PF00300.22 CBZ24212.1 - 1.6e-11 44.3 0.0 3e-08 33.6 0.0 2.2 2 0 0 2 2 2 2 Histidine phosphatase superfamily (branch 1) Pribosyltran PF00156.27 CBZ24212.1 - 0.11 12.0 0.0 0.22 11.0 0.0 1.4 1 0 0 1 1 1 0 Phosphoribosyl transferase domain Yippee-Mis18 PF03226.14 CBZ24213.1 - 0.052 13.8 0.2 1.3 9.3 0.1 2.2 2 0 0 2 2 2 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly SPX PF03105.19 CBZ24213.1 - 0.35 10.7 4.5 0.22 11.4 2.9 1.6 2 0 0 2 2 2 0 SPX domain LRR_8 PF13855.6 CBZ24214.1 - 7.4e-06 25.6 0.1 0.014 15.2 0.0 2.5 2 0 0 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 CBZ24214.1 - 0.071 13.6 4.0 10 6.7 0.8 3.8 3 1 1 4 4 4 0 Leucine Rich repeats (2 copies) UvrD-helicase PF00580.21 CBZ24215.1 - 6.3e-39 134.3 0.0 4.3e-20 72.5 0.0 2.4 1 1 1 2 2 2 2 UvrD/REP helicase N-terminal domain UvrD_C PF13361.6 CBZ24215.1 - 3.1e-27 95.9 0.0 2.6e-14 53.4 0.0 2.3 2 0 0 2 2 2 2 UvrD-like helicase C-terminal domain AAA_19 PF13245.6 CBZ24215.1 - 1.6e-25 90.2 0.0 5.7e-25 88.4 0.0 2.0 1 0 0 1 1 1 1 AAA domain UvrD_C_2 PF13538.6 CBZ24215.1 - 2.2e-09 37.0 0.0 4.8e-09 35.9 0.0 1.7 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_30 PF13604.6 CBZ24215.1 - 4.3e-09 36.4 0.2 5.5e-05 23.0 0.1 2.5 2 0 0 2 2 2 2 AAA domain Viral_helicase1 PF01443.18 CBZ24215.1 - 0.0022 17.8 0.0 3 7.5 0.0 3.4 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase ResIII PF04851.15 CBZ24215.1 - 0.039 13.9 0.0 0.15 12.0 0.0 1.9 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit NMT_C PF02799.15 CBZ24215.1 - 0.2 11.2 0.4 0.44 10.0 0.0 1.7 2 0 0 2 2 2 0 Myristoyl-CoA:protein N-myristoyltransferase, C-terminal domain Peptidase_S51 PF03575.17 CBZ24216.1 - 8e-25 87.7 0.0 6.2e-23 81.5 0.0 2.1 1 1 0 1 1 1 1 Peptidase family S51 PRKCSH-like PF12999.7 CBZ24217.1 - 1.8e-08 34.4 0.2 5.8e-07 29.5 0.0 2.2 2 0 0 2 2 2 2 Glucosidase II beta subunit-like DUF913 PF06025.12 CBZ24218.1 - 0.012 14.6 0.1 0.3 10.0 0.0 2.2 2 0 0 2 2 2 0 Domain of Unknown Function (DUF913) PH PF00169.29 CBZ24219.1 - 1.5e-10 41.5 0.0 2.7e-10 40.7 0.0 1.4 1 0 0 1 1 1 1 PH domain PH_13 PF16652.5 CBZ24219.1 - 0.034 14.0 0.0 1.8 8.3 0.0 2.3 1 1 0 1 1 1 0 Pleckstrin homology domain Ig_mannosidase PF17753.1 CBZ24219.1 - 0.14 11.9 0.0 0.29 10.9 0.0 1.5 1 0 0 1 1 1 0 Ig-fold domain DHHC PF01529.20 CBZ24220.1 - 4.2e-26 91.6 14.3 4.2e-26 91.6 14.3 2.6 2 1 0 2 2 2 1 DHHC palmitoyltransferase AAA_33 PF13671.6 CBZ24221.1 - 2.2e-07 31.1 0.2 5.8e-06 26.5 0.2 2.5 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 CBZ24221.1 - 1.3e-05 24.6 0.0 2.6e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin AAA_18 PF13238.6 CBZ24221.1 - 0.00044 20.8 0.0 0.0025 18.4 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 CBZ24221.1 - 0.0019 18.6 0.4 0.0087 16.5 0.1 2.4 2 1 0 2 2 2 1 AAA ATPase domain APS_kinase PF01583.20 CBZ24221.1 - 0.0023 17.9 0.0 0.0039 17.1 0.0 1.3 1 0 0 1 1 1 1 Adenylylsulphate kinase Cytidylate_kin PF02224.18 CBZ24221.1 - 0.0041 16.9 0.0 0.007 16.1 0.0 1.4 1 0 0 1 1 1 1 Cytidylate kinase AAA_28 PF13521.6 CBZ24221.1 - 0.024 14.9 0.0 0.14 12.4 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 CBZ24221.1 - 0.052 13.8 0.0 0.19 12.0 0.0 2.0 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 CBZ24221.1 - 0.057 13.9 0.0 0.11 13.0 0.0 1.5 1 0 0 1 1 1 0 ABC transporter RsgA_GTPase PF03193.16 CBZ24221.1 - 0.07 13.0 0.0 0.2 11.6 0.0 1.7 1 0 0 1 1 1 0 RsgA GTPase NTPase_1 PF03266.15 CBZ24221.1 - 0.12 12.3 0.0 0.22 11.4 0.0 1.4 1 0 0 1 1 1 0 NTPase AAA PF00004.29 CBZ24221.1 - 0.13 12.7 0.0 0.31 11.5 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.6 CBZ24221.1 - 0.14 12.6 0.0 0.68 10.4 0.0 2.0 2 0 0 2 2 2 0 AAA domain PRK PF00485.18 CBZ24221.1 - 0.15 11.8 0.0 0.28 10.9 0.0 1.4 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family Helicase_RecD PF05127.14 CBZ24221.1 - 0.15 11.9 0.0 1.4 8.8 0.0 2.2 2 0 0 2 2 2 0 Helicase TYW3 PF02676.14 CBZ24222.1 - 1.2e-57 194.7 0.0 1.7e-57 194.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase TYW3 Itfg2 PF15907.5 CBZ24222.1 - 0.11 11.6 0.2 0.37 9.8 0.0 1.8 1 1 1 2 2 2 0 Integrin-alpha FG-GAP repeat-containing protein 2 Prefoldin_2 PF01920.20 CBZ24223.1 - 1.8e-18 66.4 2.8 2.3e-18 66.1 2.8 1.1 1 0 0 1 1 1 1 Prefoldin subunit SlyX PF04102.12 CBZ24223.1 - 0.029 15.0 3.2 0.29 11.8 0.1 2.3 2 0 0 2 2 2 0 SlyX DASH_Dad3 PF08656.10 CBZ24223.1 - 0.041 14.0 0.7 0.041 14.0 0.7 1.9 2 0 0 2 2 2 0 DASH complex subunit Dad3 DUF4407 PF14362.6 CBZ24223.1 - 0.19 11.1 1.7 0.21 10.9 1.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Spc24 PF08286.11 CBZ24223.1 - 0.61 10.4 5.3 3 8.1 0.6 2.1 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 APG6_N PF17675.1 CBZ24223.1 - 0.8 10.2 6.9 8.3 6.9 2.1 2.1 2 0 0 2 2 2 0 Apg6 coiled-coil region CMV_1a PF12467.8 CBZ24224.1 - 0.15 12.4 0.0 0.24 11.8 0.0 1.2 1 0 0 1 1 1 0 Cucumber mosaic virus 1a protein family zf_CCCH_4 PF18345.1 CBZ24228.1 - 2.5e-18 65.5 28.9 5.6e-07 29.4 1.6 6.1 5 1 0 5 5 5 5 Zinc finger domain zf-CCCH PF00642.24 CBZ24228.1 - 1.7e-17 62.9 29.8 0.00056 19.8 0.6 5.5 5 0 0 5 5 5 5 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 CBZ24228.1 - 1.8e-11 43.6 26.7 4.5e-07 29.5 0.6 5.0 5 0 0 5 5 5 4 CCCH-type zinc finger Torus PF16131.5 CBZ24228.1 - 3e-11 44.0 21.3 0.00063 20.4 0.3 5.2 1 1 4 5 5 5 5 Torus domain zf-CCCH_3 PF15663.5 CBZ24228.1 - 1.8e-07 31.3 6.8 1.8e-07 31.3 6.8 2.6 1 1 1 2 2 2 1 Zinc-finger containing family zf-CCHC PF00098.23 CBZ24228.1 - 0.00011 22.1 11.4 0.00036 20.5 0.5 3.4 3 0 0 3 3 3 2 Zinc knuckle zf-CCHC_2 PF13696.6 CBZ24228.1 - 0.00019 21.2 4.4 0.0016 18.2 0.4 3.1 2 0 0 2 2 2 1 Zinc knuckle zf-CCCH_2 PF14608.6 CBZ24228.1 - 0.00049 20.5 1.1 0.00049 20.5 1.1 6.7 7 0 0 7 7 7 3 RNA-binding, Nab2-type zinc finger zf-C3H1 PF10650.9 CBZ24228.1 - 2.8 7.8 8.9 0.84 9.4 0.1 4.0 3 0 0 3 3 3 0 Putative zinc-finger domain zf-UBR PF02207.20 CBZ24230.1 - 1.2e-15 57.4 14.7 1.2e-15 57.4 14.7 3.1 3 0 0 3 3 3 1 Putative zinc finger in N-recognin (UBR box) Rtf2 PF04641.12 CBZ24230.1 - 3 7.1 9.0 1.5 8.1 0.7 2.5 2 0 0 2 2 2 0 Rtf2 RING-finger ACBP PF00887.19 CBZ24231.1 - 2.9e-23 81.9 0.5 5.9e-23 80.9 0.5 1.5 1 0 0 1 1 1 1 Acyl CoA binding protein DUF4486 PF14858.6 CBZ24232.1 - 0.0078 14.7 0.1 0.014 13.9 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4486) Cm_res_leader PF08077.11 CBZ24232.1 - 0.62 10.3 3.6 1.9 8.9 0.1 3.7 2 0 0 2 2 2 0 Chloramphenicol resistance gene leader peptide HA PF03457.14 CBZ24232.1 - 1.2 9.5 3.1 0.9 9.9 0.0 2.4 3 0 0 3 3 3 0 Helicase associated domain Peptidase_S9_N PF02897.15 CBZ24233.1 - 1e-117 393.5 0.4 1.4e-117 393.0 0.4 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase, N-terminal beta-propeller domain Peptidase_S9 PF00326.21 CBZ24233.1 - 3.3e-65 219.5 0.0 6e-65 218.7 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family CSS-motif PF12792.7 CBZ24233.1 - 0.059 12.8 0.0 0.19 11.2 0.0 1.8 1 0 0 1 1 1 0 CSS motif domain associated with EAL Esterase PF00756.20 CBZ24233.1 - 0.065 12.9 0.0 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 Putative esterase DUF4464 PF14713.6 CBZ24234.1 - 4.4e-84 281.5 0.2 5e-84 281.3 0.2 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4464) zf-CCCH_4 PF18044.1 CBZ24235.1 - 0.036 13.9 0.1 0.11 12.3 0.1 1.8 1 0 0 1 1 1 0 CCCH-type zinc finger GAS PF13851.6 CBZ24235.1 - 0.14 11.5 0.6 0.23 10.8 0.6 1.3 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding MT PF12777.7 CBZ24236.1 - 7.7e-07 28.4 0.0 7.7e-07 28.4 0.0 3.4 4 0 0 4 4 4 2 Microtubule-binding stalk of dynein motor Prefoldin PF02996.17 CBZ24237.1 - 9e-09 35.3 0.2 6e-08 32.6 0.0 2.0 2 0 0 2 2 2 1 Prefoldin subunit AAA PF00004.29 CBZ24238.1 - 0.0001 22.7 0.0 0.0003 21.2 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Zeta_toxin PF06414.12 CBZ24238.1 - 0.013 14.8 0.0 0.029 13.7 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin AAA_16 PF13191.6 CBZ24238.1 - 0.014 15.8 0.3 0.12 12.7 0.2 2.4 1 1 0 1 1 1 0 AAA ATPase domain DEAD PF00270.29 CBZ24239.1 - 3.5e-26 92.0 0.1 5.5e-26 91.4 0.1 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CBZ24239.1 - 1e-20 74.1 0.1 5.9e-20 71.7 0.0 2.2 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 CBZ24239.1 - 0.00015 21.8 0.0 0.00026 21.0 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 CBZ24239.1 - 0.022 15.1 0.1 0.047 14.0 0.1 1.5 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.6 CBZ24239.1 - 0.15 11.8 0.0 0.31 10.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain UPF0160 PF03690.13 CBZ24240.1 - 9.3e-120 400.0 0.0 1.1e-119 399.8 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0160) Ras PF00071.22 CBZ24241.1 - 5.1e-35 120.5 0.0 4.5e-11 42.6 0.0 3.0 3 0 0 3 3 3 3 Ras family Roc PF08477.13 CBZ24241.1 - 1.1e-19 70.8 0.2 2.4e-09 37.4 0.0 2.8 3 0 0 3 3 3 2 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CBZ24241.1 - 0.00033 20.1 0.0 1.7 8.0 0.0 2.9 3 0 0 3 3 3 2 ADP-ribosylation factor family PET117 PF15786.5 CBZ24242.1 - 0.00034 20.8 0.0 0.0004 20.6 0.0 1.2 1 0 0 1 1 1 1 PET assembly of cytochrome c oxidase, mitochondrial GvpL_GvpF PF06386.11 CBZ24243.1 - 0.058 13.3 9.5 0.12 12.3 9.5 1.5 1 0 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF Methyltransf_14 PF08484.11 CBZ24243.1 - 0.13 12.0 0.5 0.25 11.1 0.5 1.4 1 0 0 1 1 1 0 C-methyltransferase C-terminal domain PhoLip_ATPase_C PF16212.5 CBZ24245.1 - 3.7e-51 174.3 16.0 3.7e-51 174.3 16.0 1.9 2 0 0 2 2 2 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 CBZ24245.1 - 1.2e-19 69.8 0.2 3.5e-19 68.3 0.2 1.8 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Hydrolase PF00702.26 CBZ24245.1 - 2e-09 38.0 0.1 0.00076 19.8 0.0 3.5 3 0 0 3 3 3 2 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 CBZ24245.1 - 0.00022 20.8 0.1 0.00022 20.8 0.1 2.5 3 0 0 3 3 3 1 E1-E2 ATPase Cation_ATPase PF13246.6 CBZ24245.1 - 0.0095 16.0 0.0 0.18 11.9 0.0 2.8 3 0 0 3 3 3 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 CBZ24245.1 - 0.017 14.9 0.1 0.03 14.1 0.1 1.3 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase DUF805 PF05656.14 CBZ24245.1 - 9.1 6.8 9.3 11 6.5 4.2 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF805) ubiquitin PF00240.23 CBZ24246.1 - 2.1e-33 113.9 0.2 2.7e-33 113.5 0.2 1.2 1 0 0 1 1 1 1 Ubiquitin family Ribosomal_L40e PF01020.17 CBZ24246.1 - 6.8e-27 93.1 12.2 1e-26 92.5 12.2 1.3 1 0 0 1 1 1 1 Ribosomal L40e family Rad60-SLD PF11976.8 CBZ24246.1 - 5.7e-17 61.3 0.2 8e-17 60.8 0.2 1.2 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 CBZ24246.1 - 2.4e-05 24.7 0.0 0.0001 22.6 0.0 1.8 1 1 0 1 1 1 1 Ubiquitin-like domain TBK1_ULD PF18396.1 CBZ24246.1 - 0.0029 17.5 0.0 0.0038 17.1 0.0 1.2 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain Ubiquitin_5 PF18037.1 CBZ24246.1 - 0.0038 17.6 0.0 0.0076 16.6 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-like domain Rad60-SLD_2 PF13881.6 CBZ24246.1 - 0.0072 16.4 0.1 0.014 15.5 0.1 1.6 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_4 PF18036.1 CBZ24246.1 - 0.044 13.8 0.6 7.6 6.7 0.1 2.2 2 0 0 2 2 2 0 Ubiquitin-like domain EF-hand_7 PF13499.6 CBZ24247.1 - 1.9e-05 25.0 1.5 0.011 16.2 0.0 2.2 1 1 2 3 3 3 2 EF-hand domain pair EF-hand_6 PF13405.6 CBZ24247.1 - 0.00025 20.7 0.2 0.003 17.4 0.0 2.8 3 0 0 3 3 3 1 EF-hand domain EF-hand_1 PF00036.32 CBZ24247.1 - 0.00076 18.9 3.9 0.0044 16.5 0.0 3.1 3 0 0 3 3 3 1 EF hand EF-hand_8 PF13833.6 CBZ24247.1 - 0.0036 17.1 1.9 0.3 11.0 0.8 2.7 2 1 0 2 2 2 1 EF-hand domain pair EF-hand_9 PF14658.6 CBZ24247.1 - 0.12 12.7 0.0 1.7 9.0 0.0 2.2 2 0 0 2 2 2 0 EF-hand domain YokU PF14122.6 CBZ24247.1 - 2.4 8.2 4.4 4.2 7.4 1.0 2.4 1 1 2 3 3 3 0 YokU-like protein, putative antitoxin EF-hand_1 PF00036.32 CBZ24248.1 - 3e-43 142.2 12.0 1.5e-10 39.9 1.0 4.1 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 CBZ24248.1 - 1.6e-36 124.6 3.7 6.9e-19 68.1 1.2 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 CBZ24248.1 - 5e-32 109.5 11.3 1.3e-14 53.7 0.7 4.1 1 1 3 4 4 4 4 EF-hand domain pair EF-hand_6 PF13405.6 CBZ24248.1 - 2.1e-31 105.1 6.6 1.3e-09 37.2 0.1 4.4 4 1 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 CBZ24248.1 - 3.2e-28 95.9 9.4 5.8e-07 28.7 0.0 4.2 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.6 CBZ24248.1 - 6.6e-16 58.4 0.2 6.8e-09 35.9 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.7 CBZ24248.1 - 1.3e-09 37.9 0.8 5.4e-05 23.1 0.1 2.3 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 CBZ24248.1 - 6.6e-08 32.9 0.0 0.0014 18.9 0.0 2.1 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_11 PF08976.11 CBZ24248.1 - 2.6e-06 28.2 0.0 0.00063 20.6 0.0 2.1 1 1 1 2 2 2 1 EF-hand domain UPF0154 PF03672.13 CBZ24248.1 - 1.9e-05 24.6 1.0 0.035 14.1 0.0 3.3 3 1 1 4 4 4 2 Uncharacterised protein family (UPF0154) EFhand_Ca_insen PF08726.10 CBZ24248.1 - 0.00016 21.7 1.1 0.00074 19.6 0.1 2.3 2 2 0 2 2 2 1 Ca2+ insensitive EF hand Dockerin_1 PF00404.18 CBZ24248.1 - 0.00017 21.7 2.8 0.017 15.3 0.4 3.1 1 1 2 3 3 3 1 Dockerin type I domain TerB PF05099.13 CBZ24248.1 - 0.00041 20.3 0.3 0.23 11.4 0.0 2.3 1 1 1 2 2 2 2 Tellurite resistance protein TerB DUF3349 PF11829.8 CBZ24248.1 - 0.00091 20.0 0.3 3.2 8.6 0.0 2.9 1 1 2 3 3 3 1 Protein of unknown function (DUF3349) Caleosin PF05042.13 CBZ24248.1 - 0.0013 18.6 0.8 0.21 11.5 0.3 3.3 1 1 1 2 2 2 1 Caleosin related protein RNA_pol_Rpb4 PF03874.16 CBZ24248.1 - 0.0018 18.6 0.3 1.6 9.1 0.1 2.5 2 0 0 2 2 2 1 RNA polymerase Rpb4 DUF4497 PF14924.6 CBZ24248.1 - 0.0024 18.3 0.0 0.92 10.0 0.0 2.1 1 1 1 2 2 2 1 Protein of unknown function (DUF4497) Poly_export PF02563.16 CBZ24248.1 - 0.0042 17.3 0.2 0.9 9.8 0.0 3.1 1 1 0 2 2 2 1 Polysaccharide biosynthesis/export protein MotA_activ PF09114.10 CBZ24248.1 - 0.0059 16.7 0.0 0.12 12.5 0.0 2.2 2 0 0 2 2 2 1 Transcription factor MotA, activation domain DUF1103 PF06513.11 CBZ24248.1 - 0.0061 16.2 1.1 0.0071 16.0 1.1 1.1 1 0 0 1 1 1 1 Repeat of unknown function (DUF1103) SurA_N_2 PF13623.6 CBZ24248.1 - 0.015 15.2 1.4 0.56 10.1 0.2 2.2 1 1 1 2 2 2 0 SurA N-terminal domain DUF5580 PF17743.1 CBZ24248.1 - 0.019 13.6 0.0 0.019 13.5 0.0 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5580) EF-hand_14 PF17959.1 CBZ24248.1 - 0.033 14.5 0.2 5.6 7.4 0.0 2.4 1 1 1 2 2 2 0 EF-hand domain dCache_2 PF08269.11 CBZ24248.1 - 0.04 13.1 0.1 2.7 7.1 0.0 2.2 1 1 0 2 2 2 0 Cache domain Fe_hyd_lg_C PF02906.14 CBZ24248.1 - 0.045 13.4 0.2 0.11 12.1 0.2 1.7 1 1 0 1 1 1 0 Iron only hydrogenase large subunit, C-terminal domain RloB PF13707.6 CBZ24248.1 - 0.081 13.1 0.9 1.1 9.4 0.1 2.1 1 1 1 2 2 2 0 RloB-like protein EF-hand_1 PF00036.32 CBZ24249.1 - 3e-43 142.2 12.0 1.5e-10 39.9 1.0 4.1 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 CBZ24249.1 - 1.6e-36 124.6 3.7 6.9e-19 68.1 1.2 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 CBZ24249.1 - 5e-32 109.5 11.3 1.3e-14 53.7 0.7 4.1 1 1 3 4 4 4 4 EF-hand domain pair EF-hand_6 PF13405.6 CBZ24249.1 - 2.1e-31 105.1 6.6 1.3e-09 37.2 0.1 4.4 4 1 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 CBZ24249.1 - 3.2e-28 95.9 9.4 5.8e-07 28.7 0.0 4.2 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.6 CBZ24249.1 - 6.6e-16 58.4 0.2 6.8e-09 35.9 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.7 CBZ24249.1 - 1.3e-09 37.9 0.8 5.4e-05 23.1 0.1 2.3 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 CBZ24249.1 - 6.6e-08 32.9 0.0 0.0014 18.9 0.0 2.1 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_11 PF08976.11 CBZ24249.1 - 2.6e-06 28.2 0.0 0.00063 20.6 0.0 2.1 1 1 1 2 2 2 1 EF-hand domain UPF0154 PF03672.13 CBZ24249.1 - 1.9e-05 24.6 1.0 0.035 14.1 0.0 3.3 3 1 1 4 4 4 2 Uncharacterised protein family (UPF0154) EFhand_Ca_insen PF08726.10 CBZ24249.1 - 0.00016 21.7 1.1 0.00074 19.6 0.1 2.3 2 2 0 2 2 2 1 Ca2+ insensitive EF hand Dockerin_1 PF00404.18 CBZ24249.1 - 0.00017 21.7 2.8 0.017 15.3 0.4 3.1 1 1 2 3 3 3 1 Dockerin type I domain TerB PF05099.13 CBZ24249.1 - 0.00041 20.3 0.3 0.23 11.4 0.0 2.3 1 1 1 2 2 2 2 Tellurite resistance protein TerB DUF3349 PF11829.8 CBZ24249.1 - 0.00091 20.0 0.3 3.2 8.6 0.0 2.9 1 1 2 3 3 3 1 Protein of unknown function (DUF3349) Caleosin PF05042.13 CBZ24249.1 - 0.0013 18.6 0.8 0.21 11.5 0.3 3.3 1 1 1 2 2 2 1 Caleosin related protein RNA_pol_Rpb4 PF03874.16 CBZ24249.1 - 0.0018 18.6 0.3 1.6 9.1 0.1 2.5 2 0 0 2 2 2 1 RNA polymerase Rpb4 DUF4497 PF14924.6 CBZ24249.1 - 0.0024 18.3 0.0 0.92 10.0 0.0 2.1 1 1 1 2 2 2 1 Protein of unknown function (DUF4497) Poly_export PF02563.16 CBZ24249.1 - 0.0042 17.3 0.2 0.9 9.8 0.0 3.1 1 1 0 2 2 2 1 Polysaccharide biosynthesis/export protein MotA_activ PF09114.10 CBZ24249.1 - 0.0059 16.7 0.0 0.12 12.5 0.0 2.2 2 0 0 2 2 2 1 Transcription factor MotA, activation domain DUF1103 PF06513.11 CBZ24249.1 - 0.0061 16.2 1.1 0.0071 16.0 1.1 1.1 1 0 0 1 1 1 1 Repeat of unknown function (DUF1103) SurA_N_2 PF13623.6 CBZ24249.1 - 0.015 15.2 1.4 0.56 10.1 0.2 2.2 1 1 1 2 2 2 0 SurA N-terminal domain DUF5580 PF17743.1 CBZ24249.1 - 0.019 13.6 0.0 0.019 13.5 0.0 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5580) EF-hand_14 PF17959.1 CBZ24249.1 - 0.033 14.5 0.2 5.6 7.4 0.0 2.4 1 1 1 2 2 2 0 EF-hand domain dCache_2 PF08269.11 CBZ24249.1 - 0.04 13.1 0.1 2.7 7.1 0.0 2.2 1 1 0 2 2 2 0 Cache domain Fe_hyd_lg_C PF02906.14 CBZ24249.1 - 0.045 13.4 0.2 0.11 12.1 0.2 1.7 1 1 0 1 1 1 0 Iron only hydrogenase large subunit, C-terminal domain RloB PF13707.6 CBZ24249.1 - 0.081 13.1 0.9 1.1 9.4 0.1 2.1 1 1 1 2 2 2 0 RloB-like protein EF-hand_1 PF00036.32 CBZ24250.1 - 3e-43 142.2 12.0 1.5e-10 39.9 1.0 4.1 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 CBZ24250.1 - 1.6e-36 124.6 3.7 6.9e-19 68.1 1.2 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 CBZ24250.1 - 5e-32 109.5 11.3 1.3e-14 53.7 0.7 4.1 1 1 3 4 4 4 4 EF-hand domain pair EF-hand_6 PF13405.6 CBZ24250.1 - 2.1e-31 105.1 6.6 1.3e-09 37.2 0.1 4.4 4 1 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 CBZ24250.1 - 3.2e-28 95.9 9.4 5.8e-07 28.7 0.0 4.2 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.6 CBZ24250.1 - 6.6e-16 58.4 0.2 6.8e-09 35.9 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.7 CBZ24250.1 - 1.3e-09 37.9 0.8 5.4e-05 23.1 0.1 2.3 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 CBZ24250.1 - 6.6e-08 32.9 0.0 0.0014 18.9 0.0 2.1 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_11 PF08976.11 CBZ24250.1 - 2.6e-06 28.2 0.0 0.00063 20.6 0.0 2.1 1 1 1 2 2 2 1 EF-hand domain UPF0154 PF03672.13 CBZ24250.1 - 1.9e-05 24.6 1.0 0.035 14.1 0.0 3.3 3 1 1 4 4 4 2 Uncharacterised protein family (UPF0154) EFhand_Ca_insen PF08726.10 CBZ24250.1 - 0.00016 21.7 1.1 0.00074 19.6 0.1 2.3 2 2 0 2 2 2 1 Ca2+ insensitive EF hand Dockerin_1 PF00404.18 CBZ24250.1 - 0.00017 21.7 2.8 0.017 15.3 0.4 3.1 1 1 2 3 3 3 1 Dockerin type I domain TerB PF05099.13 CBZ24250.1 - 0.00041 20.3 0.3 0.23 11.4 0.0 2.3 1 1 1 2 2 2 2 Tellurite resistance protein TerB DUF3349 PF11829.8 CBZ24250.1 - 0.00091 20.0 0.3 3.2 8.6 0.0 2.9 1 1 2 3 3 3 1 Protein of unknown function (DUF3349) Caleosin PF05042.13 CBZ24250.1 - 0.0013 18.6 0.8 0.21 11.5 0.3 3.3 1 1 1 2 2 2 1 Caleosin related protein RNA_pol_Rpb4 PF03874.16 CBZ24250.1 - 0.0018 18.6 0.3 1.6 9.1 0.1 2.5 2 0 0 2 2 2 1 RNA polymerase Rpb4 DUF4497 PF14924.6 CBZ24250.1 - 0.0024 18.3 0.0 0.92 10.0 0.0 2.1 1 1 1 2 2 2 1 Protein of unknown function (DUF4497) Poly_export PF02563.16 CBZ24250.1 - 0.0042 17.3 0.2 0.9 9.8 0.0 3.1 1 1 0 2 2 2 1 Polysaccharide biosynthesis/export protein MotA_activ PF09114.10 CBZ24250.1 - 0.0059 16.7 0.0 0.12 12.5 0.0 2.2 2 0 0 2 2 2 1 Transcription factor MotA, activation domain DUF1103 PF06513.11 CBZ24250.1 - 0.0061 16.2 1.1 0.0071 16.0 1.1 1.1 1 0 0 1 1 1 1 Repeat of unknown function (DUF1103) SurA_N_2 PF13623.6 CBZ24250.1 - 0.015 15.2 1.4 0.56 10.1 0.2 2.2 1 1 1 2 2 2 0 SurA N-terminal domain DUF5580 PF17743.1 CBZ24250.1 - 0.019 13.6 0.0 0.019 13.5 0.0 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5580) EF-hand_14 PF17959.1 CBZ24250.1 - 0.033 14.5 0.2 5.6 7.4 0.0 2.4 1 1 1 2 2 2 0 EF-hand domain dCache_2 PF08269.11 CBZ24250.1 - 0.04 13.1 0.1 2.7 7.1 0.0 2.2 1 1 0 2 2 2 0 Cache domain Fe_hyd_lg_C PF02906.14 CBZ24250.1 - 0.045 13.4 0.2 0.11 12.1 0.2 1.7 1 1 0 1 1 1 0 Iron only hydrogenase large subunit, C-terminal domain RloB PF13707.6 CBZ24250.1 - 0.081 13.1 0.9 1.1 9.4 0.1 2.1 1 1 1 2 2 2 0 RloB-like protein FbpA PF05833.11 CBZ24251.1 - 1.9e-30 106.0 4.7 4.3e-21 75.2 0.0 2.5 3 0 0 3 3 3 2 Fibronectin-binding protein A N-terminus (FbpA) NFACT-R_1 PF05670.13 CBZ24251.1 - 2.3e-21 76.5 0.0 5.6e-21 75.2 0.0 1.7 1 0 0 1 1 1 1 NFACT protein RNA binding domain NFACT-C PF11923.8 CBZ24251.1 - 3.4e-09 36.6 1.5 1.5e-07 31.3 0.0 3.1 2 0 0 2 2 2 1 NFACT protein C-terminal domain Nop14 PF04147.12 CBZ24251.1 - 0.064 11.5 10.8 0.11 10.7 10.8 1.2 1 0 0 1 1 1 0 Nop14-like family SepSecS PF05889.13 CBZ24252.1 - 2.4e-92 309.7 0.0 1.9e-52 178.3 0.0 3.6 3 1 0 3 3 3 3 O-phosphoseryl-tRNA(Sec) selenium transferase, SepSecS Beta_elim_lyase PF01212.21 CBZ24252.1 - 4.2e-06 26.2 0.0 7.8e-06 25.4 0.0 1.4 1 0 0 1 1 1 1 Beta-eliminating lyase DUF3854 PF12965.7 CBZ24252.1 - 0.051 13.6 0.0 0.094 12.7 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3854) TAFII28 PF04719.14 CBZ24252.1 - 0.13 12.4 0.2 0.3 11.2 0.2 1.5 1 0 0 1 1 1 0 hTAFII28-like protein conserved region DUF2550 PF10739.9 CBZ24253.1 - 0.044 13.8 0.3 0.44 10.6 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2550) Reo_sigma1 PF01664.16 CBZ24253.1 - 0.08 12.2 0.2 0.16 11.3 0.2 1.4 1 0 0 1 1 1 0 Reovirus viral attachment protein sigma 1 EF1G PF00647.19 CBZ24254.1 - 8.9e-39 131.8 0.5 2.8e-38 130.2 0.1 2.0 2 1 1 3 3 3 1 Elongation factor 1 gamma, conserved domain GST_C PF00043.25 CBZ24254.1 - 2.1e-12 47.1 0.0 2.1e-12 47.1 0.0 2.5 3 0 0 3 3 3 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 CBZ24254.1 - 9.5e-11 41.9 0.0 3.8e-10 39.9 0.0 2.1 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 CBZ24254.1 - 6.8e-06 26.2 1.8 1.1e-05 25.6 0.0 2.3 2 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 CBZ24254.1 - 0.00022 21.2 0.0 0.00064 19.7 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 CBZ24254.1 - 0.00024 21.4 0.0 0.00069 20.0 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain PAM2 PF07145.15 CBZ24255.1 - 0.056 13.1 4.5 0.5 10.2 0.0 3.3 3 0 0 3 3 3 0 Ataxin-2 C-terminal region CCDC24 PF15669.5 CBZ24255.1 - 0.17 11.8 0.1 0.17 11.8 0.1 3.8 3 2 0 3 3 3 0 Coiled-coil domain-containing protein 24 family Chorein_N PF12624.7 CBZ24256.1 - 2.7e-17 62.9 0.0 6.3e-17 61.8 0.0 1.6 1 0 0 1 1 1 1 N-terminal region of Chorein or VPS13 VPS13 PF16908.5 CBZ24256.1 - 8.7e-16 58.4 0.7 2.2e-15 57.1 0.4 1.8 2 0 0 2 2 2 1 Vacuolar sorting-associated protein 13, N-terminal BEX PF04538.12 CBZ24256.1 - 0.36 11.4 4.0 1.1 9.8 4.0 1.9 1 0 0 1 1 1 0 Brain expressed X-linked like family PUB PF09409.10 CBZ24257.1 - 5.1e-11 42.3 0.0 9.2e-11 41.5 0.0 1.4 1 0 0 1 1 1 1 PUB domain OB_RNB PF08206.11 CBZ24257.1 - 0.15 11.8 0.0 0.38 10.5 0.0 1.6 1 0 0 1 1 1 0 Ribonuclease B OB domain CDC50 PF03381.15 CBZ24259.1 - 7.7e-67 225.7 0.1 1.2e-66 225.1 0.1 1.3 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family Retinal PF15449.6 CBZ24259.1 - 0.25 9.1 10.3 0.32 8.7 10.3 1.0 1 0 0 1 1 1 0 Retinal protein Wtap PF17098.5 CBZ24260.1 - 0.00066 19.6 1.0 0.00066 19.6 1.0 2.0 1 1 1 2 2 2 1 WTAP/Mum2p family Takusan PF04822.13 CBZ24260.1 - 0.03 14.2 1.8 0.03 14.2 1.8 2.7 3 0 0 3 3 3 0 Takusan Tmemb_cc2 PF10267.9 CBZ24260.1 - 0.03 13.5 3.3 1.6 7.8 0.2 2.3 1 1 1 2 2 2 0 Predicted transmembrane and coiled-coil 2 protein CLZ PF16526.5 CBZ24260.1 - 0.12 12.8 0.1 0.12 12.8 0.1 3.0 3 0 0 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels GAS PF13851.6 CBZ24260.1 - 0.76 9.1 10.7 1 8.7 1.0 2.6 3 0 0 3 3 3 0 Growth-arrest specific micro-tubule binding Cep57_CLD_2 PF14197.6 CBZ24260.1 - 3.6 7.7 21.2 0.38 10.9 5.8 3.1 3 0 0 3 3 3 0 Centrosome localisation domain of PPC89 CENP-F_leu_zip PF10473.9 CBZ24260.1 - 3.6 7.6 9.2 8.6 6.4 4.7 2.4 2 1 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 PRKG1_interact PF15898.5 CBZ24260.1 - 5.6 7.9 14.6 29 5.6 8.2 2.8 2 1 1 3 3 3 0 cGMP-dependent protein kinase interacting domain bZIP_2 PF07716.15 CBZ24260.1 - 7.1 6.8 18.4 0.098 12.8 6.0 3.2 3 0 0 3 3 3 0 Basic region leucine zipper LCAT PF02450.15 CBZ24261.1 - 1.4e-47 162.8 0.0 1.9e-36 126.1 0.1 2.1 1 1 0 2 2 2 2 Lecithin:cholesterol acyltransferase Abhydrolase_6 PF12697.7 CBZ24261.1 - 1.3e-05 26.0 0.8 1.3e-05 26.0 0.8 2.0 2 1 1 3 3 3 1 Alpha/beta hydrolase family Motile_Sperm PF00635.26 CBZ24262.1 - 4e-11 42.7 0.0 6.5e-11 42.0 0.0 1.2 1 0 0 1 1 1 1 MSP (Major sperm protein) domain SHS2_Rpb7-N PF03876.17 CBZ24263.1 - 1.2e-24 86.4 0.0 2e-24 85.7 0.0 1.4 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 RNA_pol_Rbc25 PF08292.12 CBZ24263.1 - 5.1e-10 39.7 0.0 7.6e-09 35.9 0.0 2.2 1 1 0 1 1 1 1 RNA polymerase III subunit Rpc25 eIF2_C PF09173.11 CBZ24264.1 - 7.4e-27 93.4 0.1 1.9e-26 92.1 0.1 1.8 1 0 0 1 1 1 1 Initiation factor eIF2 gamma, C terminal GTP_EFTU PF00009.27 CBZ24264.1 - 6.1e-23 81.4 0.1 1.6e-22 80.0 0.1 1.7 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 CBZ24264.1 - 0.0001 22.3 0.0 0.00081 19.5 0.0 2.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D2 PF03144.25 CBZ24264.1 - 0.00011 22.5 1.4 0.00051 20.4 0.5 2.4 2 0 0 2 2 2 1 Elongation factor Tu domain 2 RsgA_GTPase PF03193.16 CBZ24264.1 - 0.0012 18.7 0.6 0.045 13.7 0.1 2.4 3 0 0 3 3 3 1 RsgA GTPase MMR_HSR1_Xtn PF16897.5 CBZ24264.1 - 0.048 13.7 0.3 0.56 10.2 0.1 2.6 2 0 0 2 2 2 0 C-terminal region of MMR_HSR1 domain Dynamin_N PF00350.23 CBZ24264.1 - 0.061 13.4 0.0 0.85 9.7 0.0 2.4 2 0 0 2 2 2 0 Dynamin family GTP_EFTU PF00009.27 CBZ24265.1 - 1.2e-23 83.7 0.1 2.6e-23 82.6 0.1 1.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain eIF2_C PF09173.11 CBZ24265.1 - 9e-12 45.1 0.1 4.3e-11 42.9 0.0 2.3 2 1 0 2 2 2 1 Initiation factor eIF2 gamma, C terminal GTP_EFTU_D2 PF03144.25 CBZ24265.1 - 0.00011 22.5 0.8 0.0011 19.3 0.8 2.4 1 1 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 CBZ24265.1 - 0.00069 19.7 0.0 0.0024 17.9 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 CBZ24265.1 - 0.0017 18.3 0.2 0.046 13.6 0.0 2.2 2 0 0 2 2 2 1 RsgA GTPase MeaB PF03308.16 CBZ24265.1 - 0.13 11.2 0.1 17 4.3 0.0 2.3 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Aft1_HRA PF11786.8 CBZ24265.1 - 2.5 8.5 6.6 5.7 7.4 6.6 1.5 1 0 0 1 1 1 0 Aft1 HRA domain DUF4201 PF13870.6 CBZ24266.1 - 0.00037 20.3 11.5 0.015 15.0 2.8 2.1 2 0 0 2 2 2 2 Domain of unknown function (DUF4201) CENP-Q PF13094.6 CBZ24266.1 - 0.0019 18.5 12.2 0.0077 16.4 3.7 2.2 2 0 0 2 2 2 1 CENP-Q, a CENPA-CAD centromere complex subunit Myosin_tail_1 PF01576.19 CBZ24266.1 - 0.0033 15.3 13.5 0.0041 15.0 13.5 1.1 1 0 0 1 1 1 1 Myosin tail SpoVAD PF07451.11 CBZ24266.1 - 0.084 11.6 0.1 0.12 11.1 0.1 1.2 1 0 0 1 1 1 0 Stage V sporulation protein AD (SpoVAD) CCDC144C PF14915.6 CBZ24266.1 - 0.086 11.9 15.3 0.13 11.4 15.2 1.3 1 1 0 1 1 1 0 CCDC144C protein coiled-coil region FUSC PF04632.12 CBZ24266.1 - 0.11 11.0 9.1 0.084 11.4 4.7 1.9 1 1 1 2 2 2 0 Fusaric acid resistance protein family Cnn_1N PF07989.11 CBZ24266.1 - 0.13 12.4 11.2 0.26 11.5 2.2 3.4 2 1 0 3 3 3 0 Centrosomin N-terminal motif 1 GIT_CC PF16559.5 CBZ24266.1 - 0.15 12.0 8.6 0.61 10.0 1.4 4.3 3 1 3 6 6 5 0 GIT coiled-coil Rho guanine nucleotide exchange factor Fez1 PF06818.15 CBZ24266.1 - 0.23 11.9 12.7 2 8.8 13.0 2.0 1 1 1 2 2 2 0 Fez1 V_ATPase_I PF01496.19 CBZ24266.1 - 0.26 9.2 5.5 0.34 8.8 5.5 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF1151 PF06625.11 CBZ24266.1 - 0.26 11.2 7.6 4.1 7.4 1.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1151) Spectrin PF00435.21 CBZ24266.1 - 0.41 11.2 13.9 9 6.8 2.7 3.0 2 1 1 3 3 3 0 Spectrin repeat Cep57_CLD_2 PF14197.6 CBZ24266.1 - 0.54 10.4 14.1 0.078 13.1 2.9 3.4 3 1 0 3 3 3 0 Centrosome localisation domain of PPC89 Prominin PF05478.11 CBZ24266.1 - 0.65 7.9 8.8 1.5 6.7 8.8 1.5 1 1 0 1 1 1 0 Prominin SlyX PF04102.12 CBZ24266.1 - 0.73 10.5 13.3 5.6 7.7 0.0 3.8 2 1 0 3 3 3 0 SlyX LPD5 PF18799.1 CBZ24266.1 - 0.82 10.1 7.6 0.79 10.1 5.5 1.9 2 1 0 2 2 1 0 Large polyvalent protein-associated domain 5 BRE1 PF08647.11 CBZ24266.1 - 0.9 9.7 15.1 0.48 10.5 2.3 2.3 2 0 0 2 2 2 0 BRE1 E3 ubiquitin ligase DUF724 PF05266.14 CBZ24266.1 - 0.96 9.2 14.2 0.13 12.1 3.3 2.8 1 1 2 3 3 3 0 Protein of unknown function (DUF724) ZapB PF06005.12 CBZ24266.1 - 1 9.8 16.3 6 7.4 3.2 3.5 3 1 0 3 3 3 0 Cell division protein ZapB DUF4570 PF15134.6 CBZ24266.1 - 1.2 9.2 8.5 5 7.2 0.4 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4570) BST2 PF16716.5 CBZ24266.1 - 1.7 9.2 11.5 0.76 10.4 4.2 2.7 1 1 2 3 3 3 0 Bone marrow stromal antigen 2 DUF948 PF06103.11 CBZ24266.1 - 1.8 8.9 8.8 3.5 7.9 0.8 3.0 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) zf-C4H2 PF10146.9 CBZ24266.1 - 2.2 8.6 8.3 5.6 7.2 6.7 1.9 1 1 1 2 2 2 0 Zinc finger-containing protein SOGA PF11365.8 CBZ24266.1 - 2.4 9.4 8.8 0.49 11.5 1.2 2.6 2 1 1 3 3 3 0 Protein SOGA Spc7 PF08317.11 CBZ24266.1 - 2.5 6.9 16.5 2.3 7.0 4.9 2.2 1 1 1 2 2 2 0 Spc7 kinetochore protein Mod_r PF07200.13 CBZ24266.1 - 3.3 7.8 14.6 4.4 7.4 12.9 1.9 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein CENP-H PF05837.12 CBZ24266.1 - 3.3 8.1 17.5 13 6.2 14.2 2.6 1 1 1 2 2 2 0 Centromere protein H (CENP-H) GAS PF13851.6 CBZ24266.1 - 3.8 6.8 15.5 11 5.3 13.4 2.2 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding DUF4407 PF14362.6 CBZ24266.1 - 3.8 6.8 17.0 1.3 8.3 12.9 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) ALMT PF11744.8 CBZ24266.1 - 3.9 6.2 8.3 5.3 5.8 8.3 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter FliD_N PF02465.18 CBZ24266.1 - 4.1 8.2 11.9 3.7 8.3 3.4 3.0 2 1 1 3 3 3 0 Flagellar hook-associated protein 2 N-terminus DHR10 PF18595.1 CBZ24266.1 - 4.6 7.3 21.0 0.86 9.7 5.7 3.1 1 1 2 3 3 3 0 Designed helical repeat protein 10 domain XhlA PF10779.9 CBZ24266.1 - 8.8 6.6 6.7 41 4.5 0.4 3.0 3 0 0 3 3 3 0 Haemolysin XhlA ABC_tran_CTD PF16326.5 CBZ24266.1 - 9.7 6.5 15.4 22 5.4 5.3 3.5 2 2 1 3 3 3 0 ABC transporter C-terminal domain MRP PF09387.10 CBZ24268.1 - 1.2e-68 231.0 0.8 1.4e-68 230.7 0.8 1.1 1 0 0 1 1 1 1 Mitochondrial RNA binding protein MRP Tim17 PF02466.19 CBZ24269.1 - 1.5e-16 60.7 9.7 2.2e-16 60.2 9.7 1.3 1 1 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family DUF3287 PF11690.8 CBZ24271.1 - 2.8 7.7 7.1 0.26 11.0 1.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3287) RRM_1 PF00076.22 CBZ24272.1 - 0.16 11.8 0.2 0.4 10.5 0.2 1.6 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Skp1 PF01466.19 CBZ24273.1 - 5.2e-07 29.7 0.4 1.3e-06 28.4 0.4 1.8 1 0 0 1 1 1 1 Skp1 family, dimerisation domain AP3D1 PF06375.11 CBZ24274.1 - 0.32 11.2 9.8 0.085 13.1 2.7 2.5 2 0 0 2 2 2 0 AP-3 complex subunit delta-1 Ank_2 PF12796.7 CBZ24276.1 - 0.00071 20.1 0.2 0.26 11.9 0.0 3.5 3 0 0 3 3 3 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 CBZ24276.1 - 0.014 15.7 0.1 0.057 13.8 0.1 2.0 1 0 0 1 1 1 0 Ankyrin repeats (many copies) Ank_4 PF13637.6 CBZ24276.1 - 0.036 14.7 1.8 0.17 12.5 0.0 2.9 3 0 0 3 3 3 0 Ankyrin repeats (many copies) Ank_3 PF13606.6 CBZ24276.1 - 0.066 13.8 0.1 0.71 10.6 0.0 2.9 2 0 0 2 2 2 0 Ankyrin repeat CD225 PF04505.12 CBZ24276.1 - 0.1 12.8 0.1 0.32 11.2 0.1 1.8 1 0 0 1 1 1 0 Interferon-induced transmembrane protein zf-C3HC4_3 PF13920.6 CBZ24277.1 - 5.7e-09 35.7 24.6 5.7e-09 35.7 24.6 2.8 2 1 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) AAA PF00004.29 CBZ24278.1 - 1.1e-32 113.2 0.0 5e-22 78.7 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 CBZ24278.1 - 4e-07 30.4 0.6 0.00055 20.2 0.0 3.5 2 1 0 2 2 2 1 AAA domain AAA_33 PF13671.6 CBZ24278.1 - 5e-07 30.0 0.0 0.0057 16.8 0.0 3.3 3 0 0 3 3 2 2 AAA domain AAA_16 PF13191.6 CBZ24278.1 - 1.2e-06 29.0 7.9 1.8e-05 25.2 0.0 4.5 4 2 1 5 5 4 1 AAA ATPase domain Zot PF05707.12 CBZ24278.1 - 1.5e-06 28.0 0.6 0.089 12.4 0.0 4.4 3 2 2 5 5 4 2 Zonular occludens toxin (Zot) AAA_14 PF13173.6 CBZ24278.1 - 2.6e-05 24.3 0.0 0.001 19.1 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_7 PF12775.7 CBZ24278.1 - 0.0001 21.9 0.2 0.0015 18.0 0.1 2.3 2 0 0 2 2 2 1 P-loop containing dynein motor region TIP49 PF06068.13 CBZ24278.1 - 0.00011 21.5 0.1 0.042 13.0 0.0 2.5 2 0 0 2 2 2 1 TIP49 P-loop domain AAA_5 PF07728.14 CBZ24278.1 - 0.00016 21.7 0.0 0.009 16.0 0.0 2.8 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) Bac_DnaA PF00308.18 CBZ24278.1 - 0.00021 21.2 0.2 0.00078 19.3 0.0 1.9 2 0 0 2 2 2 1 Bacterial dnaA protein RNA_helicase PF00910.22 CBZ24278.1 - 0.00028 21.2 0.0 0.056 13.8 0.0 2.6 2 0 0 2 2 2 1 RNA helicase DUF2075 PF09848.9 CBZ24278.1 - 0.00032 20.1 0.1 1.5 8.0 0.0 3.4 2 1 1 3 3 3 1 Uncharacterized conserved protein (DUF2075) IstB_IS21 PF01695.17 CBZ24278.1 - 0.00042 20.1 0.0 0.041 13.6 0.0 2.6 2 0 0 2 2 2 1 IstB-like ATP binding protein NACHT PF05729.12 CBZ24278.1 - 0.0008 19.4 0.1 0.053 13.4 0.0 2.7 2 0 0 2 2 2 1 NACHT domain AAA_30 PF13604.6 CBZ24278.1 - 0.0035 17.1 0.0 0.15 11.8 0.0 2.8 2 0 0 2 2 2 1 AAA domain RuvB_N PF05496.12 CBZ24278.1 - 0.0039 17.0 0.0 0.075 12.8 0.0 2.6 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain Torsin PF06309.11 CBZ24278.1 - 0.0056 16.8 0.2 0.15 12.2 0.1 2.5 2 0 0 2 2 2 1 Torsin RsgA_GTPase PF03193.16 CBZ24278.1 - 0.0067 16.4 0.1 0.032 14.1 0.0 2.0 2 0 0 2 2 2 1 RsgA GTPase Sigma54_activat PF00158.26 CBZ24278.1 - 0.0068 16.1 0.6 0.67 9.6 0.1 2.8 3 0 0 3 3 2 1 Sigma-54 interaction domain Mg_chelatase PF01078.21 CBZ24278.1 - 0.0095 15.3 0.2 0.064 12.6 0.1 2.2 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI ABC_tran PF00005.27 CBZ24278.1 - 0.01 16.3 0.4 0.14 12.7 0.0 2.8 3 0 0 3 3 2 0 ABC transporter AAA_18 PF13238.6 CBZ24278.1 - 0.032 14.8 0.0 0.77 10.3 0.0 2.5 2 0 0 2 2 2 0 AAA domain DUF3135 PF11333.8 CBZ24278.1 - 0.042 14.1 0.1 0.19 12.0 0.1 2.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3135) AAA_2 PF07724.14 CBZ24278.1 - 0.049 13.8 0.0 0.18 11.9 0.0 1.9 2 0 0 2 2 1 0 AAA domain (Cdc48 subfamily) PhoH PF02562.16 CBZ24278.1 - 0.05 13.0 1.5 0.24 10.8 0.0 2.6 2 1 0 3 3 3 0 PhoH-like protein APS_kinase PF01583.20 CBZ24278.1 - 0.055 13.4 0.1 0.48 10.3 0.1 2.4 2 0 0 2 2 2 0 Adenylylsulphate kinase T2SSE PF00437.20 CBZ24278.1 - 0.062 12.4 0.0 0.2 10.7 0.0 1.8 1 0 0 1 1 1 0 Type II/IV secretion system protein TsaE PF02367.17 CBZ24278.1 - 0.067 13.2 0.2 0.5 10.4 0.1 2.2 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE NB-ARC PF00931.22 CBZ24278.1 - 0.072 12.3 0.0 0.18 11.0 0.0 1.6 1 0 0 1 1 1 0 NB-ARC domain AAA_29 PF13555.6 CBZ24278.1 - 0.099 12.4 1.0 3.4 7.5 0.3 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain SRP54 PF00448.22 CBZ24278.1 - 0.12 12.0 0.5 0.6 9.7 0.0 2.3 3 0 0 3 3 2 0 SRP54-type protein, GTPase domain ATPase PF06745.13 CBZ24278.1 - 0.13 11.6 0.2 4.7 6.5 0.0 2.5 2 0 0 2 2 2 0 KaiC Microtub_bd PF16796.5 CBZ24278.1 - 0.21 11.5 0.0 0.47 10.4 0.0 1.5 1 0 0 1 1 1 0 Microtubule binding DUF4189 PF13827.6 CBZ24279.1 - 0.021 15.3 0.5 0.021 15.3 0.5 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4189) AAA_12 PF13087.6 CBZ24280.1 - 2.8e-49 167.5 0.0 4.5e-49 166.8 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 CBZ24280.1 - 8.9e-32 110.9 8.8 9.1e-18 65.0 0.2 3.4 2 1 0 3 3 3 2 AAA domain AAA_19 PF13245.6 CBZ24280.1 - 6.3e-07 29.8 0.0 3.4e-06 27.5 0.0 2.3 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 CBZ24280.1 - 3.2e-06 27.0 9.7 0.0017 18.1 0.6 3.7 4 0 0 4 4 4 2 AAA domain Helicase_RecD PF05127.14 CBZ24280.1 - 0.0056 16.5 0.1 0.35 10.7 0.0 2.9 2 0 0 2 2 2 1 Helicase AAA_22 PF13401.6 CBZ24280.1 - 0.0094 16.2 0.2 0.31 11.3 0.0 3.2 3 0 0 3 3 3 1 AAA domain ResIII PF04851.15 CBZ24280.1 - 0.0096 15.9 0.0 0.063 13.3 0.0 2.2 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit Viral_helicase1 PF01443.18 CBZ24280.1 - 0.024 14.4 0.4 9.2 5.9 0.0 3.4 3 0 0 3 3 3 0 Viral (Superfamily 1) RNA helicase PhoH PF02562.16 CBZ24280.1 - 0.15 11.5 0.0 3.6 7.0 0.0 2.3 2 0 0 2 2 2 0 PhoH-like protein UvrD-helicase PF00580.21 CBZ24280.1 - 0.25 10.8 0.0 0.25 10.8 0.0 2.7 4 0 0 4 4 4 0 UvrD/REP helicase N-terminal domain Bromodomain PF00439.25 CBZ24282.1 - 4.4e-21 74.8 0.0 1.5e-11 44.2 0.0 2.3 2 0 0 2 2 2 2 Bromodomain BSD PF03909.17 CBZ24282.1 - 0.063 13.3 0.0 8.5 6.5 0.0 2.5 2 0 0 2 2 2 0 BSD domain Mito_carr PF00153.27 CBZ24283.1 - 6.1e-43 144.7 5.7 5.2e-17 61.5 0.1 3.9 3 1 0 3 3 3 3 Mitochondrial carrier protein Orthopox_C10L PF07020.11 CBZ24283.1 - 1.5 9.7 7.1 0.89 10.3 2.8 2.2 2 0 0 2 2 2 0 Orthopoxvirus C10L protein DZR PF12773.7 CBZ24284.1 - 5e-05 23.2 1.2 0.0068 16.4 0.1 2.6 2 1 0 2 2 2 1 Double zinc ribbon zinc_ribbon_10 PF10058.9 CBZ24284.1 - 0.08 12.7 3.7 5.1 6.9 0.1 3.9 4 0 0 4 4 4 0 Predicted integral membrane zinc-ribbon metal-binding protein Zn_ribbon_SprT PF17283.2 CBZ24284.1 - 0.099 12.6 11.3 0.13 12.2 1.0 3.4 3 1 0 3 3 3 0 SprT-like zinc ribbon domain zf-DNL PF05180.12 CBZ24284.1 - 0.16 11.9 0.3 18 5.4 0.0 2.9 3 0 0 3 3 3 0 DNL zinc finger Zn-ribbon_8 PF09723.10 CBZ24284.1 - 0.22 11.7 3.6 1.5 9.0 0.1 2.8 2 2 0 2 2 2 0 Zinc ribbon domain zf-LITAF-like PF10601.9 CBZ24284.1 - 0.42 10.9 7.1 5.2 7.4 0.0 3.6 3 1 0 3 3 3 0 LITAF-like zinc ribbon domain Zn_Tnp_IS1595 PF12760.7 CBZ24284.1 - 3.7 7.6 9.8 17 5.5 0.2 4.0 4 0 0 4 4 4 0 Transposase zinc-ribbon domain Kelch_4 PF13418.6 CBZ24285.1 - 7e-10 38.8 1.0 1.8 8.6 0.0 5.8 6 0 0 6 6 6 4 Galactose oxidase, central domain Kelch_5 PF13854.6 CBZ24285.1 - 5.6e-05 23.0 9.3 0.067 13.2 0.0 5.3 6 0 0 6 6 6 2 Kelch motif Kelch_2 PF07646.15 CBZ24285.1 - 0.00092 19.1 2.1 14 5.8 0.0 4.9 5 0 0 5 5 5 1 Kelch motif Kelch_6 PF13964.6 CBZ24285.1 - 0.018 15.3 0.2 40 4.7 0.0 4.1 6 0 0 6 6 6 0 Kelch motif Kelch_1 PF01344.25 CBZ24285.1 - 0.065 12.8 9.1 3.2 7.4 0.1 4.6 5 0 0 5 5 5 0 Kelch motif Peptidase_C97 PF05903.14 CBZ24286.1 - 4e-24 85.2 0.0 9.9e-24 83.9 0.0 1.6 1 1 1 2 2 2 1 PPPDE putative peptidase domain DUF4796 PF16044.5 CBZ24286.1 - 0.014 15.0 0.0 0.02 14.5 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4796) Peptidase_C97 PF05903.14 CBZ24287.1 - 3.6e-21 75.6 0.0 5.1e-21 75.1 0.0 1.3 1 0 0 1 1 1 1 PPPDE putative peptidase domain DUF4796 PF16044.5 CBZ24287.1 - 0.038 13.6 0.0 0.053 13.1 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4796) CBP_BcsR PF10945.8 CBZ24288.1 - 0.12 11.8 3.4 0.96 9.0 0.1 2.4 2 0 0 2 2 2 0 Cellulose biosynthesis protein BcsR Flagellar_rod PF05149.12 CBZ24289.1 - 2.9e-105 351.9 20.5 2.9e-105 351.9 20.5 1.8 2 0 0 2 2 2 1 Paraflagellar rod protein Glutaredoxin2_C PF04399.13 CBZ24289.1 - 0.047 13.5 4.8 0.68 9.8 0.5 3.2 3 0 0 3 3 3 0 Glutaredoxin 2, C terminal domain TBCC_N PF16752.5 CBZ24289.1 - 0.13 12.7 13.9 2.1 8.8 0.3 4.4 5 1 1 6 6 6 0 Tubulin-specific chaperone C N-terminal domain DUF1460 PF07313.12 CBZ24289.1 - 1.5 8.1 7.4 5.3 6.4 6.6 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1460) HBD PF18534.1 CBZ24289.1 - 4.1 7.6 6.5 3.7 7.7 0.2 3.5 2 1 1 3 3 3 0 Helical bundle domain Plk4_PB2 PF18409.1 CBZ24289.1 - 7.5 7.3 10.3 1.8 9.3 0.1 3.8 3 1 0 3 3 3 0 Polo-like Kinase 4 Polo Box 2 Nif11 PF07862.11 CBZ24290.1 - 0.17 12.2 0.1 0.4 11.0 0.1 1.6 1 0 0 1 1 1 0 Nif11 domain Histone PF00125.24 CBZ24291.1 - 1.6e-11 44.7 1.1 2e-11 44.3 1.1 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 CBZ24291.1 - 0.002 18.4 0.2 0.0042 17.3 0.2 1.6 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone GMP_synt_C PF00958.22 CBZ24291.1 - 0.018 15.1 1.3 0.026 14.6 0.8 1.5 1 1 1 2 2 2 0 GMP synthase C terminal domain F-box-like PF12937.7 CBZ24296.1 - 0.38 10.7 2.0 0.53 10.2 0.1 2.3 2 1 0 2 2 2 0 F-box-like Glyco_hydro_47 PF01532.20 CBZ24297.1 - 7.9e-06 25.0 0.0 1.4e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 InaF-motif PF15018.6 CBZ24297.1 - 2.6 8.0 6.0 4.9 7.1 6.0 1.5 1 0 0 1 1 1 0 TRP-interacting helix SET PF00856.28 CBZ24298.1 - 3.6e-09 37.2 0.0 9.9e-09 35.8 0.0 1.9 1 1 0 1 1 1 1 SET domain KORA PF16509.5 CBZ24299.1 - 0.029 14.6 1.3 0.054 13.8 1.2 1.7 1 1 0 1 1 1 0 TrfB plasmid transcriptional repressor CNOT1_TTP_bind PF16417.5 CBZ24299.1 - 0.034 13.3 0.8 0.054 12.7 0.8 1.3 1 0 0 1 1 1 0 CCR4-NOT transcription complex subunit 1 TTP binding domain Prominin PF05478.11 CBZ24299.1 - 0.069 11.1 1.0 0.072 11.0 1.0 1.1 1 0 0 1 1 1 0 Prominin rRNA_processing PF08524.11 CBZ24299.1 - 0.14 12.2 13.6 0.23 11.5 13.6 1.3 1 0 0 1 1 1 0 rRNA processing DUF4296 PF14129.6 CBZ24299.1 - 0.15 12.6 4.8 1.4 9.6 1.7 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4296) Presenilin PF01080.17 CBZ24299.1 - 0.18 10.5 9.5 0.23 10.2 9.5 1.0 1 0 0 1 1 1 0 Presenilin DUF1128 PF06569.11 CBZ24299.1 - 0.19 11.8 3.4 1.5 8.9 0.1 2.3 1 1 0 2 2 2 0 Protein of unknown function (DUF1128) L31 PF09784.9 CBZ24299.1 - 0.2 12.1 5.5 0.09 13.2 3.0 1.6 1 1 0 1 1 1 0 Mitochondrial ribosomal protein L31 V_ATPase_I PF01496.19 CBZ24299.1 - 0.32 8.9 9.0 0.37 8.6 9.0 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family FAM178 PF14816.6 CBZ24299.1 - 0.33 9.9 4.1 0.34 9.8 4.1 1.3 1 0 0 1 1 1 0 Family of unknown function, FAM178 Tho2 PF11262.8 CBZ24299.1 - 0.79 8.9 7.9 0.32 10.2 5.7 1.3 1 1 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 YtxH PF12732.7 CBZ24299.1 - 3.5 8.2 9.0 15 6.2 2.2 2.4 1 1 1 2 2 2 0 YtxH-like protein Coq4 PF05019.13 CBZ24300.1 - 1.6e-47 161.7 0.0 1.8e-47 161.5 0.0 1.0 1 0 0 1 1 1 1 Coenzyme Q (ubiquinone) biosynthesis protein Coq4 DnaJ PF00226.31 CBZ24301.1 - 4e-12 46.1 0.1 8.3e-12 45.1 0.1 1.5 1 0 0 1 1 1 1 DnaJ domain GcrA PF07750.11 CBZ24301.1 - 0.0062 17.0 0.0 0.015 15.7 0.0 1.7 1 0 0 1 1 1 1 GcrA cell cycle regulator P4Ha_N PF08336.11 CBZ24301.1 - 0.03 14.3 0.1 0.079 13.0 0.1 1.7 1 1 0 1 1 1 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region Rhodanese PF00581.20 CBZ24302.1 - 1.4e-05 25.6 0.0 1.6e-05 25.4 0.0 1.1 1 0 0 1 1 1 1 Rhodanese-like domain Rhodanese PF00581.20 CBZ24303.1 - 2.2e-11 44.2 0.0 2.9e-11 43.8 0.0 1.2 1 0 0 1 1 1 1 Rhodanese-like domain Rhodanese PF00581.20 CBZ24304.1 - 7e-15 55.5 0.0 8.2e-15 55.2 0.0 1.1 1 0 0 1 1 1 1 Rhodanese-like domain DUF4859 PF16151.5 CBZ24304.1 - 0.034 14.0 0.0 0.048 13.5 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4859) PBP PF01161.20 CBZ24304.1 - 0.11 12.8 0.0 0.12 12.7 0.0 1.1 1 0 0 1 1 1 0 Phosphatidylethanolamine-binding protein Mito_carr PF00153.27 CBZ24304.1 - 0.12 12.3 0.0 0.18 11.7 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial carrier protein DB_JBP1 PF18526.1 CBZ24305.1 - 1.3e-85 285.4 6.0 3.5e-85 284.0 4.2 2.2 2 0 0 2 2 2 1 Thymine dioxygenase JBP1 DNA-binding domain Tet_JBP PF12851.7 CBZ24305.1 - 3.5e-21 75.9 0.0 4.7e-17 62.3 0.0 2.4 1 1 1 2 2 2 2 Oxygenase domain of the 2OGFeDO superfamily B2-adapt-app_C PF09066.10 CBZ24305.1 - 0.09 12.9 0.0 0.18 11.9 0.0 1.5 1 0 0 1 1 1 0 Beta2-adaptin appendage, C-terminal sub-domain RACo_linker PF17650.1 CBZ24305.1 - 0.11 12.4 0.0 0.31 10.9 0.0 1.8 1 0 0 1 1 1 0 RACo linker region Cyt-b5 PF00173.28 CBZ24306.1 - 7.7e-21 74.0 0.3 9.5e-21 73.7 0.3 1.1 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain RTC_insert PF05189.13 CBZ24308.1 - 0.073 13.6 0.1 0.12 12.9 0.1 1.3 1 0 0 1 1 1 0 RNA 3'-terminal phosphate cyclase (RTC), insert domain Laminin_G_2 PF02210.24 CBZ24309.1 - 0.00077 20.0 0.5 0.24 12.0 0.0 3.3 4 0 0 4 4 4 2 Laminin G domain IQ PF00612.27 CBZ24309.1 - 0.0092 15.7 0.6 0.058 13.2 0.0 2.7 2 0 0 2 2 2 1 IQ calmodulin-binding motif LRR_6 PF13516.6 CBZ24310.1 - 1.7e-16 58.8 2.5 0.032 14.3 0.0 7.5 8 0 0 8 8 8 4 Leucine Rich repeat EF-hand_6 PF13405.6 CBZ24311.1 - 0.0027 17.5 0.0 0.32 11.0 0.0 2.6 2 0 0 2 2 2 1 EF-hand domain RIIa PF02197.17 CBZ24311.1 - 0.12 12.1 0.0 0.22 11.2 0.0 1.5 1 0 0 1 1 1 0 Regulatory subunit of type II PKA R-subunit EF-hand_7 PF13499.6 CBZ24311.1 - 0.12 12.9 0.0 0.19 12.2 0.0 1.4 1 0 0 1 1 1 0 EF-hand domain pair KASH_CCD PF14662.6 CBZ24312.1 - 0.02 14.7 82.5 0.14 11.9 18.6 6.1 2 2 5 7 7 7 0 Coiled-coil region of CCDC155 or KASH ADIP PF11559.8 CBZ24312.1 - 3 7.9 90.9 0.49 10.5 14.5 7.8 2 2 4 7 7 7 0 Afadin- and alpha -actinin-Binding DUF2353 PF09789.9 CBZ24312.1 - 7.9 5.7 65.5 3.1 7.1 23.4 4.2 2 2 1 3 3 3 0 Uncharacterized coiled-coil protein (DUF2353) DUF4257 PF14074.6 CBZ24313.1 - 0.02 15.1 0.1 0.035 14.3 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4257) PHO4 PF01384.20 CBZ24314.1 - 9.7e-106 353.6 13.9 1.2e-105 353.4 13.9 1.1 1 0 0 1 1 1 1 Phosphate transporter family HECW_N PF16562.5 CBZ24314.1 - 0.17 11.7 0.0 0.3 10.9 0.0 1.3 1 0 0 1 1 1 0 N-terminal domain of E3 ubiquitin-protein ligase HECW1 and 2 MMS19_N PF14500.6 CBZ24316.1 - 2.6e-42 145.2 4.5 9.2e-42 143.4 4.5 2.0 1 0 0 1 1 1 1 Dos2-interacting transcription regulator of RNA-Pol-II CLASP_N PF12348.8 CBZ24316.1 - 0.00061 19.4 1.2 0.0034 17.0 0.3 2.5 2 0 0 2 2 2 1 CLASP N terminal Thymidylate_kin PF02223.17 CBZ24317.1 - 5.3e-14 52.3 0.0 1.8e-13 50.6 0.0 1.8 1 1 0 1 1 1 1 Thymidylate kinase Ribosomal_L35Ae PF01247.18 CBZ24318.1 - 2.9e-33 113.9 0.8 4.3e-33 113.3 0.8 1.3 1 0 0 1 1 1 1 Ribosomal protein L35Ae RimM PF01782.18 CBZ24318.1 - 6.7e-05 23.0 1.6 0.15 12.3 0.4 2.7 2 1 0 2 2 2 2 RimM N-terminal domain adh_short PF00106.25 CBZ24320.1 - 3e-30 105.1 0.0 3.9e-26 91.7 0.0 2.2 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 CBZ24320.1 - 5.7e-19 68.6 0.0 8.6e-16 58.2 0.0 2.2 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CBZ24320.1 - 2.3e-05 24.4 0.0 4e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 CBZ24320.1 - 6.1e-05 22.6 0.0 9.4e-05 22.0 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 CBZ24320.1 - 0.0024 17.3 0.0 0.0051 16.3 0.0 1.5 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 CBZ24320.1 - 0.0043 17.0 0.0 0.0092 15.9 0.0 1.6 1 0 0 1 1 1 1 NAD(P)H-binding SRP40_C PF05022.12 CBZ24321.1 - 3.1e-12 47.2 0.5 6.3e-12 46.2 0.5 1.6 1 0 0 1 1 1 1 SRP40, C-terminal domain BLOC1S3 PF15753.5 CBZ24321.1 - 0.47 10.6 5.1 0.11 12.7 1.6 1.6 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex 1 subunit 3 DUF4692 PF15763.5 CBZ24321.1 - 5.5 7.4 9.3 0.16 12.4 0.9 2.2 1 1 1 2 2 2 0 Regulator of human erythroid cell expansion (RHEX) WD40 PF00400.32 CBZ24322.1 - 2.1e-27 94.8 28.9 1.3e-06 29.0 0.4 7.4 7 1 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBZ24322.1 - 9.9e-05 22.6 0.2 0.036 14.4 0.0 3.9 2 2 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain PSP1 PF04468.12 CBZ24323.1 - 3.8e-23 81.6 0.3 5.9e-23 81.0 0.3 1.3 1 0 0 1 1 1 1 PSP1 C-terminal conserved region Seryl_tRNA_N PF02403.22 CBZ24324.1 - 0.0085 16.3 6.0 0.0085 16.3 6.0 3.0 2 1 1 3 3 3 1 Seryl-tRNA synthetase N-terminal domain BLOC1_2 PF10046.9 CBZ24324.1 - 0.019 15.2 8.4 0.54 10.6 0.8 2.6 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 PLU-1 PF08429.11 CBZ24324.1 - 0.045 12.9 5.1 0.071 12.3 5.1 1.2 1 0 0 1 1 1 0 PLU-1-like protein PI3K_P85_iSH2 PF16454.5 CBZ24324.1 - 0.25 10.9 7.9 1.6 8.3 8.0 2.1 1 1 0 1 1 1 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain Lipase_chap PF03280.14 CBZ24324.1 - 0.53 10.2 7.6 1.3 8.9 7.6 1.6 1 0 0 1 1 1 0 Proteobacterial lipase chaperone protein FlxA PF14282.6 CBZ24324.1 - 1 9.4 13.4 1.5 8.9 6.9 2.7 1 1 1 2 2 2 0 FlxA-like protein Spectrin PF00435.21 CBZ24324.1 - 2.1 8.9 14.1 10 6.7 3.3 3.3 2 1 1 3 3 3 0 Spectrin repeat SKA2 PF16740.5 CBZ24324.1 - 2.6 7.8 13.8 6.1 6.7 1.0 3.1 1 1 1 2 2 2 0 Spindle and kinetochore-associated protein 2 NPV_P10 PF05531.12 CBZ24324.1 - 2.8 8.5 7.0 5.8e+02 1.0 6.9 2.8 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein Mif2_N PF15624.6 CBZ24324.1 - 2.8 8.6 10.3 0.59 10.8 2.3 2.5 1 1 1 2 2 2 0 Kinetochore CENP-C fungal homologue, Mif2, N-terminal DUF16 PF01519.16 CBZ24324.1 - 4 8.0 9.9 1.5 9.4 1.6 2.6 1 1 1 2 2 2 0 Protein of unknown function DUF16 GPS2_interact PF15784.5 CBZ24324.1 - 7 7.2 13.8 0.08 13.4 1.3 3.4 2 1 2 4 4 4 0 G-protein pathway suppressor 2-interacting domain ERM PF00769.19 CBZ24324.1 - 7.3 6.3 18.0 0.12 12.2 11.0 1.6 2 0 0 2 2 1 0 Ezrin/radixin/moesin family DEAD PF00270.29 CBZ24325.1 - 3.3e-16 59.6 0.4 2.4e-13 50.2 0.0 2.6 3 0 0 3 3 3 2 DEAD/DEAH box helicase Helicase_C PF00271.31 CBZ24325.1 - 1.2e-14 54.6 0.2 2.8e-14 53.4 0.2 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain UTP25 PF06862.12 CBZ24325.1 - 0.0055 15.5 0.0 1.1 7.9 0.0 2.9 2 1 1 3 3 3 2 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 DUF4164 PF13747.6 CBZ24327.1 - 0.026 14.8 10.9 0.026 14.8 10.9 3.7 2 2 1 3 3 3 0 Domain of unknown function (DUF4164) AAA_23 PF13476.6 CBZ24327.1 - 0.46 10.9 14.6 8.2 6.9 0.1 2.3 2 0 0 2 2 2 0 AAA domain DUF4250 PF14056.6 CBZ24327.1 - 0.52 10.3 5.9 0.19 11.7 0.3 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4250) TMPIT PF07851.13 CBZ24327.1 - 1.7 7.8 17.9 1.5 8.0 6.3 2.3 2 0 0 2 2 2 0 TMPIT-like protein DUF2046 PF09755.9 CBZ24327.1 - 2.1 7.5 33.5 0.39 9.9 23.6 2.9 2 1 0 2 2 2 0 Uncharacterized conserved protein H4 (DUF2046) NPV_P10 PF05531.12 CBZ24327.1 - 2.6 8.6 11.8 1.3 9.6 4.7 3.3 3 1 0 3 3 3 0 Nucleopolyhedrovirus P10 protein APG6_N PF17675.1 CBZ24327.1 - 3.2 8.3 44.9 0.6 10.6 21.1 3.0 2 1 1 3 3 3 0 Apg6 coiled-coil region PIN_8 PF18476.1 CBZ24327.1 - 4.3 7.1 12.9 6.3 6.6 5.9 2.3 2 0 0 2 2 2 0 PIN like domain DUF5345 PF17280.2 CBZ24327.1 - 7.1 6.7 12.3 0.28 11.2 3.7 2.8 2 0 0 2 2 2 0 Family of unknown function (DUF5345) Cupin_8 PF13621.6 CBZ24327.1 - 10 5.8 6.8 1.5 8.5 1.3 2.0 1 1 1 2 2 2 0 Cupin-like domain GDA1_CD39 PF01150.17 CBZ24328.1 - 3.1e-63 213.9 0.0 8.9e-63 212.4 0.0 1.6 1 1 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family Ppx-GppA PF02541.16 CBZ24328.1 - 0.014 14.9 0.0 0.028 13.9 0.0 1.4 1 0 0 1 1 1 0 Ppx/GppA phosphatase family LRR_8 PF13855.6 CBZ24329.1 - 3.3e-13 49.2 11.9 5.1e-06 26.2 4.6 3.1 1 1 2 3 3 3 3 Leucine rich repeat LRR_4 PF12799.7 CBZ24329.1 - 7.3e-11 42.1 26.6 0.00029 21.2 1.2 3.4 1 1 3 4 4 4 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 CBZ24329.1 - 8.5e-06 25.6 12.8 6.7 7.7 0.4 5.7 5 1 0 5 5 5 4 Leucine Rich Repeat LRR_9 PF14580.6 CBZ24329.1 - 0.092 12.2 1.4 0.27 10.7 1.2 1.7 1 1 1 2 2 2 0 Leucine-rich repeat PDZ_6 PF17820.1 CBZ24331.1 - 1.5e-09 37.6 0.0 4e-09 36.2 0.0 1.8 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 CBZ24331.1 - 0.0002 21.6 0.0 0.00041 20.6 0.0 1.5 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 CBZ24331.1 - 0.00027 21.2 0.0 0.0006 20.1 0.0 1.6 1 0 0 1 1 1 1 PDZ domain MORN PF02493.20 CBZ24332.1 - 5.4e-18 63.7 14.1 3.1e-05 23.6 0.8 4.7 4 0 0 4 4 4 4 MORN repeat Pkinase PF00069.25 CBZ24333.1 - 3.8e-57 193.7 0.0 4.9e-57 193.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ24333.1 - 2.6e-27 95.7 0.0 4.3e-27 95.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 CBZ24333.1 - 5.9e-07 28.8 0.6 8.2e-07 28.3 0.6 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 CBZ24333.1 - 2.9e-05 23.5 1.2 5.4e-05 22.6 1.2 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 CBZ24333.1 - 0.00011 22.3 1.5 0.00012 22.1 0.2 1.9 2 0 0 2 2 2 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 CBZ24333.1 - 0.03 13.1 0.5 0.054 12.3 0.5 1.4 1 0 0 1 1 1 0 Fungal protein kinase RIO1 PF01163.22 CBZ24333.1 - 0.045 13.4 0.7 0.21 11.2 0.4 2.1 2 0 0 2 2 2 0 RIO1 family Kinase-like PF14531.6 CBZ24333.1 - 0.083 12.2 0.1 0.2 10.9 0.1 1.9 1 1 0 1 1 1 0 Kinase-like YchF-GTPase_C PF06071.13 CBZ24333.1 - 0.094 12.9 0.4 3.4 7.9 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF933) Nop PF01798.18 CBZ24334.1 - 7.8e-80 267.6 0.0 1.1e-79 267.1 0.0 1.2 1 0 0 1 1 1 1 snoRNA binding domain, fibrillarin NOP5NT PF08156.13 CBZ24334.1 - 1.5e-16 60.5 0.0 4.2e-16 59.1 0.0 1.8 1 0 0 1 1 1 1 NOP5NT (NUC127) domain Amastin PF07344.11 CBZ24337.1 - 3.6e-41 140.6 24.0 1.1e-25 90.3 6.4 2.2 2 0 0 2 2 2 2 Amastin surface glycoprotein Amastin PF07344.11 CBZ24338.1 - 2.8e-52 176.7 18.9 1e-33 116.4 8.8 2.3 2 0 0 2 2 2 2 Amastin surface glycoprotein TadE PF07811.12 CBZ24338.1 - 2.9 8.2 9.9 0.3 11.4 0.8 3.4 3 0 0 3 3 3 0 TadE-like protein Pterin_4a PF01329.19 CBZ24340.1 - 3.1e-09 36.9 0.0 1.8e-08 34.4 0.0 2.1 1 1 0 1 1 1 1 Pterin 4 alpha carbinolamine dehydratase HP1451_C PF18472.1 CBZ24340.1 - 0.05 13.6 0.0 0.1 12.6 0.0 1.5 1 0 0 1 1 1 0 HP1451 C-terminal domain COPI_assoc PF08507.10 CBZ24341.1 - 3.8e-06 27.0 18.8 4.7e-06 26.7 18.8 1.1 1 0 0 1 1 1 1 COPI associated protein RNase_T PF00929.24 CBZ24342.1 - 6.9e-09 36.5 0.0 1.2e-08 35.7 0.0 1.4 1 0 0 1 1 1 1 Exonuclease Iso_dh PF00180.20 CBZ24344.1 - 6.4e-74 249.2 0.0 7.4e-74 249.0 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Vps5 PF09325.10 CBZ24345.1 - 0.022 14.3 6.6 0.04 13.4 6.6 1.4 1 0 0 1 1 1 0 Vps5 C terminal like SEN1_N PF12726.7 CBZ24345.1 - 0.066 11.4 1.9 0.076 11.2 0.7 1.6 2 0 0 2 2 2 0 SEN1 N terminal ComX PF05952.12 CBZ24345.1 - 0.16 12.0 0.1 0.34 10.9 0.1 1.5 1 0 0 1 1 1 0 Bacillus competence pheromone ComX UPF0242 PF06785.11 CBZ24345.1 - 0.3 11.2 6.9 0.57 10.3 6.9 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Exonuc_VII_L PF02601.15 CBZ24345.1 - 0.5 9.9 7.6 1 8.9 7.6 1.4 1 0 0 1 1 1 0 Exonuclease VII, large subunit Fez1 PF06818.15 CBZ24345.1 - 0.58 10.6 10.9 1.3 9.4 10.9 1.5 1 0 0 1 1 1 0 Fez1 DUF3584 PF12128.8 CBZ24345.1 - 0.96 6.9 15.3 1.3 6.4 15.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Fmp27_WPPW PF10359.9 CBZ24345.1 - 1.1 8.1 5.8 1.6 7.5 5.8 1.2 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain Ead_Ea22 PF13935.6 CBZ24345.1 - 1.8 9.2 10.5 4.8 7.8 10.6 1.7 1 1 0 1 1 1 0 Ead/Ea22-like protein SlyX PF04102.12 CBZ24345.1 - 2.5 8.8 13.5 1.2 9.8 8.3 3.0 3 0 0 3 3 3 0 SlyX V_ATPase_I PF01496.19 CBZ24345.1 - 2.9 5.7 4.4 4.3 5.1 4.4 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Spc24 PF08286.11 CBZ24345.1 - 2.9 8.2 7.7 5.5 7.3 7.5 1.6 1 1 0 1 1 1 0 Spc24 subunit of Ndc80 Atg14 PF10186.9 CBZ24345.1 - 3.6 6.6 9.2 6.3 5.8 9.2 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 ADIP PF11559.8 CBZ24345.1 - 7.6 6.6 15.0 0.29 11.2 8.8 1.8 2 1 0 2 2 2 0 Afadin- and alpha -actinin-Binding Sec23_trunk PF04811.15 CBZ24346.1 - 3e-40 138.3 0.0 7.3e-20 71.6 0.0 2.2 1 1 1 2 2 2 2 Sec23/Sec24 trunk domain Sec23_helical PF04815.15 CBZ24346.1 - 3.4e-20 71.8 0.0 1.1e-19 70.1 0.0 1.9 2 0 0 2 2 2 1 Sec23/Sec24 helical domain Sec23_BS PF08033.12 CBZ24346.1 - 8.3e-19 68.1 0.0 1.6e-18 67.2 0.0 1.5 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain Gelsolin PF00626.22 CBZ24346.1 - 3.4e-07 30.1 0.0 7.1e-07 29.0 0.0 1.5 1 0 0 1 1 1 1 Gelsolin repeat Ima1_N PF09779.9 CBZ24346.1 - 0.035 15.0 0.7 0.062 14.2 0.7 1.4 1 0 0 1 1 1 0 Ima1 N-terminal domain zf-Sec23_Sec24 PF04810.15 CBZ24346.1 - 0.15 12.2 9.2 0.32 11.1 9.2 1.6 1 0 0 1 1 1 0 Sec23/Sec24 zinc finger ThiC_Rad_SAM PF01964.18 CBZ24346.1 - 0.46 9.2 3.1 0.36 9.6 0.1 1.9 2 0 0 2 2 2 0 Radical SAM ThiC family BT1 PF03092.16 CBZ24349.1 - 4.3e-198 658.8 9.2 5.1e-198 658.6 9.2 1.0 1 0 0 1 1 1 1 BT1 family BT1 PF03092.16 CBZ24350.1 - 3e-259 860.6 4.3 3.4e-259 860.4 4.3 1.0 1 0 0 1 1 1 1 BT1 family BT1 PF03092.16 CBZ24351.1 - 8e-248 822.9 6.2 9.1e-248 822.7 6.2 1.0 1 0 0 1 1 1 1 BT1 family BT1 PF03092.16 CBZ24352.1 - 2.9e-260 864.0 5.6 3.5e-260 863.7 5.6 1.1 1 0 0 1 1 1 1 BT1 family Dak1 PF02733.17 CBZ24353.1 - 4.1e-92 308.4 1.1 4.1e-92 308.4 1.1 1.4 2 0 0 2 2 2 1 Dak1 domain Dak2 PF02734.17 CBZ24353.1 - 5.3e-37 127.4 3.4 5.3e-37 127.4 3.4 1.7 2 0 0 2 2 2 1 DAK2 domain DUF4658 PF15555.6 CBZ24354.1 - 0.018 15.2 0.8 0.044 13.9 0.8 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4658) zf-C3HC4_3 PF13920.6 CBZ24355.1 - 1.5e-05 24.8 15.6 7.1e-05 22.6 15.6 2.0 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CBZ24355.1 - 0.3 11.1 11.8 0.7 9.9 11.8 1.7 1 1 0 1 1 1 0 zinc-RING finger domain zf-C3HC4_3 PF13920.6 CBZ24356.1 - 1.4e-06 28.0 16.9 5.5e-06 26.2 16.9 1.8 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CBZ24356.1 - 0.02 14.9 12.3 0.039 13.9 12.3 1.5 1 1 0 1 1 1 0 zinc-RING finger domain Prok-RING_4 PF14447.6 CBZ24356.1 - 0.78 9.7 14.5 1.6 8.6 10.1 2.1 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 4F5 PF04419.14 CBZ24357.1 - 3.1e-10 40.7 7.9 4.1e-10 40.4 7.9 1.2 1 0 0 1 1 1 1 4F5 protein family zf-met2 PF12907.7 CBZ24357.1 - 8.2e-07 29.1 0.4 8.2e-07 29.1 0.4 1.7 2 0 0 2 2 2 1 Zinc-binding zf-H2C2_2 PF13465.6 CBZ24357.1 - 0.024 15.1 2.3 0.28 11.7 0.3 2.3 2 0 0 2 2 2 0 Zinc-finger double domain Fer4_18 PF13746.6 CBZ24357.1 - 0.1 12.8 1.1 0.12 12.6 1.1 1.1 1 0 0 1 1 1 0 4Fe-4S dicluster domain DUF3504 PF12012.8 CBZ24357.1 - 0.11 12.4 0.8 0.13 12.2 0.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3504) zf-C2H2_4 PF13894.6 CBZ24357.1 - 0.14 13.1 1.9 0.51 11.3 0.3 2.3 2 0 0 2 2 2 0 C2H2-type zinc finger Peptidase_M8 PF01457.16 CBZ24358.1 - 7.4e-255 846.6 4.6 8.7e-255 846.4 4.6 1.0 1 0 0 1 1 1 1 Leishmanolysin Zincin_1 PF06262.11 CBZ24358.1 - 0.025 14.7 0.0 0.063 13.4 0.0 1.6 1 0 0 1 1 1 0 Zincin-like metallopeptidase Peptidase_M57 PF12388.8 CBZ24358.1 - 0.071 12.7 0.0 0.15 11.6 0.0 1.5 1 0 0 1 1 1 0 Dual-action HEIGH metallo-peptidase Peptidase_M8 PF01457.16 CBZ24359.1 - 1.8e-246 818.9 2.0 2.2e-246 818.7 2.0 1.0 1 0 0 1 1 1 1 Leishmanolysin Peptidase_M57 PF12388.8 CBZ24359.1 - 0.066 12.8 1.3 0.19 11.3 0.0 2.3 3 0 0 3 3 3 0 Dual-action HEIGH metallo-peptidase Peptidase_M8 PF01457.16 CBZ24360.1 - 2.4e-245 815.2 3.7 2.8e-245 815.0 3.7 1.0 1 0 0 1 1 1 1 Leishmanolysin Peptidase_M8 PF01457.16 CBZ24361.1 - 6.7e-254 843.5 7.3 7.8e-254 843.2 7.3 1.0 1 0 0 1 1 1 1 Leishmanolysin Zincin_1 PF06262.11 CBZ24361.1 - 0.021 14.9 0.0 0.051 13.7 0.0 1.6 1 0 0 1 1 1 0 Zincin-like metallopeptidase Peptidase_M57 PF12388.8 CBZ24361.1 - 0.076 12.6 0.0 0.16 11.5 0.0 1.5 1 0 0 1 1 1 0 Dual-action HEIGH metallo-peptidase Peptidase_M8 PF01457.16 CBZ24362.1 - 9.6e-248 823.1 2.5 1.1e-247 822.9 2.5 1.0 1 0 0 1 1 1 1 Leishmanolysin Pkinase PF00069.25 CBZ24365.1 - 1.6e-63 214.5 0.0 1.9e-63 214.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ24365.1 - 1.8e-27 96.3 0.0 1.1e-26 93.7 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CBZ24365.1 - 0.0026 17.1 0.0 0.004 16.5 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 CBZ24365.1 - 0.0083 15.5 0.1 0.014 14.8 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Baculo_11_kDa PF06143.11 CBZ24366.1 - 0.51 9.9 2.4 1.2 8.7 2.4 1.5 1 0 0 1 1 1 0 Baculovirus 11 kDa family NAD_Gly3P_dh_C PF07479.14 CBZ24367.1 - 8.4e-46 155.8 1.7 1e-45 155.5 0.5 1.7 2 0 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus NAD_Gly3P_dh_N PF01210.23 CBZ24367.1 - 1.8e-45 154.7 0.1 3.6e-45 153.8 0.0 1.5 2 0 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus UDPG_MGDP_dh_N PF03721.14 CBZ24367.1 - 0.00047 19.8 0.0 0.00083 19.0 0.0 1.4 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain F420_oxidored PF03807.17 CBZ24367.1 - 0.0017 18.9 0.0 0.0038 17.8 0.0 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.15 CBZ24367.1 - 0.0043 17.2 0.0 0.022 15.0 0.0 2.1 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase DUF1188 PF06690.11 CBZ24367.1 - 0.16 11.5 0.0 0.3 10.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1188) Ilar_coat PF01787.16 CBZ24368.1 - 0.076 12.8 0.2 0.2 11.4 0.2 1.7 1 0 0 1 1 1 0 Ilarvirus coat protein DUF1281 PF06924.11 CBZ24369.1 - 0.00093 18.8 0.5 0.011 15.3 0.2 2.7 2 0 0 2 2 2 1 Protein of unknown function (DUF1281) DUF2347 PF09804.9 CBZ24369.1 - 0.41 10.2 0.0 0.41 10.2 0.0 4.3 4 1 1 5 5 5 0 Uncharacterized conserved protein (DUF2347) DUF4145 PF13643.6 CBZ24369.1 - 0.59 10.3 7.0 1.5 9.0 0.1 4.4 3 1 1 4 4 4 0 Domain of unknown function (DUF4145) FAD_SOX PF18371.1 CBZ24369.1 - 0.96 9.8 4.6 2 8.8 0.2 3.8 2 1 0 2 2 2 0 Flavin adenine dinucleotide (FAD)-dependent sulfhydryl oxidase Pox_A_type_inc PF04508.12 CBZ24369.1 - 1.5 8.8 13.2 0.22 11.4 1.1 3.9 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat Amidinotransf PF02274.17 CBZ24371.1 - 0.1 11.6 0.0 0.15 11.1 0.0 1.2 1 0 0 1 1 1 0 Amidinotransferase ADH_zinc_N PF00107.26 CBZ24372.1 - 9.2e-15 54.8 0.0 1.7e-14 53.9 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 CBZ24372.1 - 6e-10 39.0 0.1 3e-09 36.7 0.1 2.0 2 1 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 CBZ24372.1 - 8e-09 36.6 0.0 1.4e-08 35.9 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 CBZ24373.1 - 4.3e-17 62.3 0.0 8.6e-17 61.3 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 CBZ24373.1 - 6.5e-14 53.1 0.0 1.4e-13 52.1 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 CBZ24373.1 - 3.8e-05 23.5 0.0 9e-05 22.3 0.0 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain CAF1A PF12253.8 CBZ24374.1 - 5.6e-09 36.0 0.3 5.6e-09 36.0 0.3 3.2 2 1 1 3 3 3 1 Chromatin assembly factor 1 subunit A Borrelia_P83 PF05262.11 CBZ24374.1 - 8.9 4.7 12.9 20 3.5 12.9 1.5 1 0 0 1 1 1 0 Borrelia P83/100 protein ABC1 PF03109.16 CBZ24376.1 - 5.7e-23 81.3 0.0 1.1e-22 80.4 0.0 1.5 1 0 0 1 1 1 1 ABC1 family Pkinase PF00069.25 CBZ24376.1 - 0.058 12.7 0.0 0.092 12.1 0.0 1.2 1 0 0 1 1 1 0 Protein kinase domain Endonuclease_NS PF01223.23 CBZ24377.1 - 2.9e-50 171.2 0.0 5.9e-50 170.2 0.0 1.5 1 1 0 1 1 1 1 DNA/RNA non-specific endonuclease Endonuclea_NS_2 PF13930.6 CBZ24377.1 - 0.078 13.1 0.2 0.26 11.4 0.2 1.8 1 1 0 1 1 1 0 DNA/RNA non-specific endonuclease SPX PF03105.19 CBZ24379.1 - 0.034 14.1 0.4 0.04 13.8 0.4 1.1 1 0 0 1 1 1 0 SPX domain Apt1 PF10351.9 CBZ24379.1 - 0.099 11.5 1.8 0.13 11.1 1.8 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Secretin_N_2 PF07655.13 CBZ24379.1 - 0.83 10.2 19.7 3 8.5 19.7 1.9 1 0 0 1 1 1 0 Secretin N-terminal domain Herpes_capsid PF06112.11 CBZ24379.1 - 0.97 9.5 23.9 3.2 7.8 23.9 1.8 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein DUF4614 PF15391.6 CBZ24379.1 - 4.5 7.2 11.2 8.8 6.3 11.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) zf-CCCH PF00642.24 CBZ24380.1 - 0.00026 20.8 2.3 0.00046 20.0 2.3 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 CBZ24380.1 - 0.025 14.6 3.1 0.044 13.8 3.1 1.4 1 0 0 1 1 1 0 Zinc finger domain 2OG-FeII_Oxy_5 PF13759.6 CBZ24381.1 - 0.009 16.4 0.0 0.018 15.4 0.0 1.4 1 0 0 1 1 1 1 Putative 2OG-Fe(II) oxygenase DUF1751 PF08551.10 CBZ24383.1 - 0.00034 21.1 1.3 0.0012 19.4 0.4 2.1 2 0 0 2 2 2 1 Eukaryotic integral membrane protein (DUF1751) Med3 PF11593.8 CBZ24384.1 - 2 7.5 17.5 3.5 6.7 17.5 1.3 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal HEAT PF02985.22 CBZ24385.1 - 0.0018 18.4 36.1 0.013 15.7 0.1 9.1 9 0 0 9 9 9 3 HEAT repeat HEAT_2 PF13646.6 CBZ24385.1 - 0.068 13.6 32.7 0.34 11.3 0.1 8.5 7 1 2 9 9 9 0 HEAT repeats RRM_1 PF00076.22 CBZ24386.1 - 3.3e-39 132.5 1.5 1.8e-15 56.5 0.0 5.4 5 1 0 5 5 5 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 CBZ24386.1 - 1.4e-06 27.9 0.0 0.0032 17.1 0.0 3.4 4 0 0 4 4 4 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 CBZ24386.1 - 2.5e-06 27.2 0.0 0.0011 18.8 0.0 3.3 3 0 0 3 3 3 1 Occluded RNA-recognition motif RRM_Rrp7 PF17799.1 CBZ24386.1 - 0.0035 17.2 0.0 2.9 7.7 0.0 3.2 3 0 0 3 3 3 2 Rrp7 RRM-like N-terminal domain RRM_7 PF16367.5 CBZ24386.1 - 0.01 15.9 0.0 0.088 12.9 0.0 2.5 3 0 0 3 3 3 0 RNA recognition motif Nup35_RRM_2 PF14605.6 CBZ24386.1 - 0.21 11.6 0.1 1.8 8.6 0.1 2.5 3 0 0 3 3 3 0 Nup53/35/40-type RNA recognition motif Aa_trans PF01490.18 CBZ24387.1 - 9.9e-06 24.5 1.1 1.1e-05 24.3 1.1 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Bet_v_1 PF00407.19 CBZ24387.1 - 0.087 12.7 0.0 0.13 12.2 0.0 1.3 1 0 0 1 1 1 0 Pathogenesis-related protein Bet v I family Aa_trans PF01490.18 CBZ24388.1 - 1.4e-39 136.0 37.6 3.8e-39 134.6 37.6 1.6 1 1 0 1 1 1 1 Transmembrane amino acid transporter protein PEN-2 PF10251.9 CBZ24388.1 - 1.7 9.1 10.3 15 6.1 0.0 4.2 3 1 1 4 4 4 0 Presenilin enhancer-2 subunit of gamma secretase dCMP_cyt_deam_1 PF00383.23 CBZ24389.1 - 4.4e-14 52.2 0.0 3.2e-11 43.0 0.0 2.6 1 1 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 CBZ24389.1 - 1.5e-12 47.5 0.4 9.8e-06 25.4 0.0 3.1 2 1 0 2 2 2 2 MafB19-like deaminase Bd3614-deam PF14439.6 CBZ24389.1 - 0.0022 18.1 1.6 0.36 10.9 0.1 2.3 2 0 0 2 2 2 2 Bd3614-like deaminase MTHFR PF02219.17 CBZ24392.1 - 0.00098 18.5 0.1 0.45 9.8 0.0 3.2 3 0 0 3 3 3 2 Methylenetetrahydrofolate reductase MTHFR PF02219.17 CBZ24393.1 - 0.014 14.7 0.3 12 5.1 0.0 3.5 4 0 0 4 4 4 0 Methylenetetrahydrofolate reductase WD40 PF00400.32 CBZ24394.1 - 3.2e-63 208.1 17.7 1.3e-08 35.3 0.1 8.2 8 0 0 8 8 8 8 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBZ24394.1 - 7.4e-23 80.7 3.5 0.00073 19.8 0.1 7.4 1 1 7 8 8 8 7 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 CBZ24394.1 - 5.9e-13 48.8 2.3 0.042 13.2 0.1 6.5 3 3 4 7 7 7 5 WD40-like domain Nup160 PF11715.8 CBZ24394.1 - 5.9e-09 35.1 12.5 0.09 11.4 0.1 5.6 2 1 5 7 7 7 4 Nucleoporin Nup120/160 eIF2A PF08662.11 CBZ24394.1 - 8.1e-09 35.6 2.9 0.00023 21.1 0.1 3.2 1 1 3 4 4 4 4 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 CBZ24394.1 - 0.0053 15.8 7.0 10 5.0 0.5 5.4 1 1 6 7 7 7 1 WD40 region of Ge1, enhancer of mRNA-decapping protein CEP19 PF14933.6 CBZ24394.1 - 0.06 13.6 0.0 0.098 13.0 0.0 1.2 1 0 0 1 1 1 0 CEP19-like protein DUF4934 PF16288.5 CBZ24394.1 - 0.067 13.1 0.4 7.4 6.5 0.0 3.4 4 0 0 4 4 4 0 Domain of unknown function (DUF4934) DUF5570 PF17731.1 CBZ24394.1 - 0.12 12.5 11.4 2.9 8.0 0.0 5.1 1 1 3 5 5 5 0 Family of unknown function (DUF5570) DFRP_C PF16543.5 CBZ24395.1 - 5.5e-13 49.2 8.0 5.5e-13 49.2 8.0 2.8 2 1 0 2 2 2 1 DRG Family Regulatory Proteins, Tma46 AAA_34 PF13872.6 CBZ24396.1 - 0.084 11.8 0.0 0.15 10.9 0.0 1.3 1 0 0 1 1 1 0 P-loop containing NTP hydrolase pore-1 BetaGal_dom3 PF13363.6 CBZ24397.1 - 0.048 13.2 0.1 0.18 11.4 0.0 2.0 2 0 0 2 2 2 0 Beta-galactosidase, domain 3 Clathrin_H_link PF13838.6 CBZ24397.1 - 0.17 11.8 1.7 1.4 8.9 0.2 2.8 2 0 0 2 2 2 0 Clathrin-H-link TPR_2 PF07719.17 CBZ24398.1 - 7.2e-05 22.6 0.3 1.5 9.1 0.0 4.3 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.6 CBZ24398.1 - 0.0062 16.8 6.4 0.0077 16.5 4.7 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat DUF2153 PF09921.9 CBZ24398.1 - 0.026 14.3 0.2 0.06 13.2 0.2 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2153) TPR_1 PF00515.28 CBZ24398.1 - 0.047 13.5 0.4 2.6 8.0 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_8 PF13181.6 CBZ24398.1 - 0.1 12.9 0.2 20 5.7 0.1 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_10 PF13374.6 CBZ24398.1 - 0.68 9.9 9.5 0.21 11.5 2.6 3.1 3 1 0 3 3 3 0 Tetratricopeptide repeat Pkinase PF00069.25 CBZ24399.1 - 5.9e-23 81.6 0.0 2.3e-18 66.5 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ24399.1 - 2e-05 24.0 0.0 0.00027 20.3 0.0 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase A_deaminase PF00962.22 CBZ24400.1 - 2.8e-09 36.8 1.6 4.5e-05 22.9 0.2 3.2 3 0 0 3 3 3 3 Adenosine/AMP deaminase NTF2 PF02136.20 CBZ24401.1 - 4.7e-27 94.9 0.6 5.1e-27 94.8 0.6 1.0 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain DUF4440 PF14534.6 CBZ24401.1 - 0.00021 21.6 0.0 0.00025 21.4 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) Lumazine_bd_2 PF12893.7 CBZ24401.1 - 0.0047 17.6 0.1 0.0093 16.6 0.1 1.5 1 0 0 1 1 1 1 Putative lumazine-binding SnoaL_2 PF12680.7 CBZ24401.1 - 0.044 14.4 0.1 0.056 14.1 0.1 1.1 1 0 0 1 1 1 0 SnoaL-like domain Nop16 PF09420.10 CBZ24402.1 - 1e-14 55.1 2.4 2.9e-11 43.8 0.3 2.1 1 1 1 2 2 2 2 Ribosome biogenesis protein Nop16 YpjP PF14005.6 CBZ24402.1 - 0.058 13.4 0.2 0.085 12.9 0.2 1.2 1 0 0 1 1 1 0 YpjP-like protein Histone PF00125.24 CBZ24403.1 - 4.2e-41 140.4 5.2 4.7e-41 140.2 5.2 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 CBZ24403.1 - 1e-05 25.7 0.2 1e-05 25.7 0.2 1.6 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-S PF15630.6 CBZ24403.1 - 6.3e-05 23.3 0.0 0.00011 22.5 0.0 1.3 1 0 0 1 1 1 1 CENP-S protein CENP-T_C PF15511.6 CBZ24403.1 - 0.00012 22.1 0.1 0.00023 21.3 0.1 1.4 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold Bromo_TP PF07524.13 CBZ24403.1 - 0.044 13.8 0.0 0.069 13.2 0.0 1.2 1 0 0 1 1 1 0 Bromodomain associated TFIID-31kDa PF02291.15 CBZ24403.1 - 0.06 13.4 0.1 0.082 13.0 0.1 1.2 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Mitochondr_Som1 PF11093.8 CBZ24403.1 - 0.07 13.1 0.1 0.11 12.4 0.1 1.6 1 1 0 1 1 1 0 Mitochondrial export protein Som1 FKBP_C PF00254.28 CBZ24405.1 - 1.1e-25 89.8 0.0 1.6e-25 89.3 0.0 1.2 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase DUF2895 PF11444.8 CBZ24405.1 - 0.093 12.1 0.0 0.13 11.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2895) IQ PF00612.27 CBZ24406.1 - 0.16 11.8 62.5 0.21 11.5 2.5 9.6 9 0 0 9 9 9 0 IQ calmodulin-binding motif DUF1216 PF06746.11 CBZ24406.1 - 0.2 11.6 0.6 0.49 10.4 0.6 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1216) Cas_Cas4 PF01930.17 CBZ24406.1 - 3.5 7.7 5.1 3.5 7.7 0.3 2.4 2 0 0 2 2 2 0 Domain of unknown function DUF83 Ras PF00071.22 CBZ24407.1 - 2.5e-59 199.5 0.1 3e-59 199.3 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CBZ24407.1 - 2.5e-33 114.9 0.0 4.5e-33 114.0 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CBZ24407.1 - 9.5e-15 54.5 0.1 1.2e-14 54.1 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 CBZ24407.1 - 1.1e-05 25.1 0.1 2.8e-05 23.7 0.1 1.7 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 CBZ24407.1 - 1.3e-05 25.3 0.0 2e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 CBZ24407.1 - 0.00019 21.4 0.3 0.015 15.2 0.1 2.3 1 1 0 2 2 2 1 RsgA GTPase Ploopntkinase3 PF18751.1 CBZ24407.1 - 0.00035 20.6 0.0 0.74 9.7 0.0 2.2 2 0 0 2 2 2 2 P-loop Nucleotide Kinase3 SRPRB PF09439.10 CBZ24407.1 - 0.0013 18.2 0.3 0.0024 17.4 0.0 1.5 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit DLIC PF05783.11 CBZ24407.1 - 0.003 16.4 0.0 1.3 7.8 0.0 2.1 2 0 0 2 2 2 2 Dynein light intermediate chain (DLIC) AAA_22 PF13401.6 CBZ24407.1 - 0.0051 17.1 0.0 0.011 16.0 0.0 1.7 1 1 0 1 1 1 1 AAA domain Gtr1_RagA PF04670.12 CBZ24407.1 - 0.0074 15.7 0.0 0.0088 15.4 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_7 PF12775.7 CBZ24407.1 - 0.011 15.3 0.2 0.017 14.6 0.2 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region FeoB_N PF02421.18 CBZ24407.1 - 0.017 14.7 0.0 0.032 13.8 0.0 1.4 1 0 0 1 1 1 0 Ferrous iron transport protein B AAA_24 PF13479.6 CBZ24407.1 - 0.019 14.7 0.0 0.04 13.6 0.0 1.7 2 0 0 2 2 2 0 AAA domain Septin PF00735.18 CBZ24407.1 - 0.03 13.6 0.1 0.052 12.8 0.1 1.3 1 0 0 1 1 1 0 Septin Amidase02_C PF12123.8 CBZ24407.1 - 0.032 13.9 0.1 0.27 10.9 0.0 2.3 2 0 0 2 2 2 0 N-acetylmuramoyl-l-alanine amidase AAA_5 PF07728.14 CBZ24407.1 - 0.054 13.5 0.0 0.096 12.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) ABC_tran PF00005.27 CBZ24407.1 - 0.17 12.4 0.1 0.24 11.9 0.1 1.5 1 1 0 1 1 1 0 ABC transporter AAA_16 PF13191.6 CBZ24407.1 - 0.19 12.1 0.0 0.31 11.4 0.0 1.4 1 1 0 1 1 1 0 AAA ATPase domain IF-2B PF01008.17 CBZ24413.1 - 6.9e-41 140.3 0.0 4.9e-39 134.2 0.0 2.1 2 0 0 2 2 2 2 Initiation factor 2 subunit family Spc7 PF08317.11 CBZ24414.1 - 2.9 6.7 30.7 0.14 11.0 11.6 3.6 3 2 0 3 3 3 0 Spc7 kinetochore protein Histone PF00125.24 CBZ24415.1 - 4.2e-41 140.4 5.2 4.7e-41 140.2 5.2 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 CBZ24415.1 - 1e-05 25.7 0.2 1e-05 25.7 0.2 1.6 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-S PF15630.6 CBZ24415.1 - 6.3e-05 23.3 0.0 0.00011 22.5 0.0 1.3 1 0 0 1 1 1 1 CENP-S protein CENP-T_C PF15511.6 CBZ24415.1 - 0.00012 22.1 0.1 0.00023 21.3 0.1 1.4 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold Bromo_TP PF07524.13 CBZ24415.1 - 0.044 13.8 0.0 0.069 13.2 0.0 1.2 1 0 0 1 1 1 0 Bromodomain associated TFIID-31kDa PF02291.15 CBZ24415.1 - 0.06 13.4 0.1 0.082 13.0 0.1 1.2 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Mitochondr_Som1 PF11093.8 CBZ24415.1 - 0.07 13.1 0.1 0.11 12.4 0.1 1.6 1 1 0 1 1 1 0 Mitochondrial export protein Som1 ArnB_C PF18677.1 CBZ24416.1 - 0.47 10.6 1.6 0.98 9.6 1.6 1.5 1 0 0 1 1 1 0 Archaellum regulatory network B, C-terminal domain Histone PF00125.24 CBZ24417.1 - 4.2e-41 140.4 5.2 4.7e-41 140.2 5.2 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 CBZ24417.1 - 1e-05 25.7 0.2 1e-05 25.7 0.2 1.6 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-S PF15630.6 CBZ24417.1 - 6.3e-05 23.3 0.0 0.00011 22.5 0.0 1.3 1 0 0 1 1 1 1 CENP-S protein CENP-T_C PF15511.6 CBZ24417.1 - 0.00012 22.1 0.1 0.00023 21.3 0.1 1.4 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold Bromo_TP PF07524.13 CBZ24417.1 - 0.044 13.8 0.0 0.069 13.2 0.0 1.2 1 0 0 1 1 1 0 Bromodomain associated TFIID-31kDa PF02291.15 CBZ24417.1 - 0.06 13.4 0.1 0.082 13.0 0.1 1.2 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Mitochondr_Som1 PF11093.8 CBZ24417.1 - 0.07 13.1 0.1 0.11 12.4 0.1 1.6 1 1 0 1 1 1 0 Mitochondrial export protein Som1 P34-Arc PF04045.14 CBZ24418.1 - 0.0051 16.5 0.0 0.0075 16.0 0.0 1.2 1 0 0 1 1 1 1 Arp2/3 complex, 34 kD subunit p34-Arc PNP_UDP_1 PF01048.20 CBZ24419.1 - 5.3e-44 150.2 0.4 6.2e-44 150.0 0.4 1.1 1 0 0 1 1 1 1 Phosphorylase superfamily Mito_carr PF00153.27 CBZ24420.1 - 2e-22 78.9 0.8 2e-08 34.0 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein RRM_1 PF00076.22 CBZ24421.1 - 3.5e-10 39.5 0.0 7.5e-10 38.5 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) MSP1_C PF07462.11 CBZ24421.1 - 2.2 6.9 6.8 3.4 6.3 6.8 1.2 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus Dicty_REP PF05086.12 CBZ24421.1 - 6.2 4.7 4.4 8.2 4.3 4.4 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein CH_2 PF06294.11 CBZ24422.1 - 1.1e-24 86.3 0.0 2.2e-24 85.4 0.0 1.5 1 0 0 1 1 1 1 CH-like domain in sperm protein CAMSAP_CH PF11971.8 CBZ24422.1 - 0.0024 17.6 0.0 0.0047 16.7 0.0 1.4 1 0 0 1 1 1 1 CAMSAP CH domain DnaJ PF00226.31 CBZ24423.1 - 3.8e-07 30.1 0.1 6.5e-07 29.4 0.1 1.3 1 0 0 1 1 1 1 DnaJ domain YABBY PF04690.13 CBZ24424.1 - 0.037 14.6 0.1 0.06 13.9 0.1 1.2 1 0 0 1 1 1 0 YABBY protein Sec8_exocyst PF04048.14 CBZ24425.1 - 9.8 6.1 9.6 1.3 8.9 0.3 3.4 2 1 0 3 3 3 0 Sec8 exocyst complex component specific domain MIF4G PF02854.19 CBZ24426.1 - 1.2e-13 51.1 3.2 1.9e-13 50.5 0.5 2.4 3 0 0 3 3 3 1 MIF4G domain Herpes_BLRF2 PF05812.12 CBZ24426.1 - 0.012 15.7 1.1 0.035 14.2 1.1 1.7 1 0 0 1 1 1 0 Herpesvirus BLRF2 protein DUF4041 PF13250.6 CBZ24426.1 - 0.11 12.3 0.1 0.5 10.3 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4041) 7TMR-DISM_7TM PF07695.11 CBZ24428.1 - 0.24 11.3 8.8 0.41 10.5 8.8 1.3 1 0 0 1 1 1 0 7TM diverse intracellular signalling LsmAD PF06741.13 CBZ24430.1 - 1.4e-18 67.2 1.9 4.2e-18 65.7 1.9 1.9 1 0 0 1 1 1 1 LsmAD domain SM-ATX PF14438.6 CBZ24430.1 - 4e-11 42.9 0.0 7.4e-11 42.0 0.0 1.5 1 0 0 1 1 1 1 Ataxin 2 SM domain TPR_2 PF07719.17 CBZ24432.1 - 0.056 13.6 1.6 4.5 7.6 0.6 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat CMV_1a PF12467.8 CBZ24432.1 - 0.82 10.0 3.3 1.5 9.2 0.9 2.5 2 0 0 2 2 2 0 Cucumber mosaic virus 1a protein family zf-C3HC4_3 PF13920.6 CBZ24433.1 - 1.4e-15 56.9 10.3 2.4e-15 56.1 10.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 CBZ24433.1 - 4.7e-09 36.0 10.2 7.9e-09 35.2 10.2 1.3 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 CBZ24433.1 - 4.4e-06 26.9 12.8 8.7e-06 26.0 12.8 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 CBZ24433.1 - 0.0085 15.9 14.1 0.016 15.0 14.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CBZ24433.1 - 0.089 12.8 11.4 0.19 11.7 11.4 1.5 1 0 0 1 1 1 0 zinc-RING finger domain zf-RING_4 PF14570.6 CBZ24433.1 - 0.4 10.5 9.1 0.8 9.6 9.1 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-P11 PF03854.14 CBZ24433.1 - 2.8 7.7 9.8 6.5 6.5 9.8 1.6 1 0 0 1 1 1 0 P-11 zinc finger TPH PF13868.6 CBZ24434.1 - 1.7e-64 217.6 156.5 1.7e-64 217.6 156.5 2.0 1 1 0 1 1 1 1 Trichohyalin-plectin-homology domain Ras PF00071.22 CBZ24435.1 - 4.2e-54 182.5 0.1 5.2e-54 182.2 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CBZ24435.1 - 3.2e-30 104.8 0.0 9.4e-30 103.3 0.0 1.7 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CBZ24435.1 - 5.1e-11 42.3 0.0 6.8e-11 41.9 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 CBZ24435.1 - 5.5e-07 29.3 0.0 3.8e-05 23.3 0.0 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 CBZ24435.1 - 5.5e-06 26.5 0.0 1.1e-05 25.4 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 CBZ24435.1 - 8.3e-05 22.0 0.1 0.00012 21.5 0.1 1.5 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 CBZ24435.1 - 0.00071 19.5 0.0 0.032 14.2 0.0 2.2 2 0 0 2 2 2 1 RsgA GTPase AAA_18 PF13238.6 CBZ24435.1 - 0.0015 19.1 0.0 0.0055 17.2 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 CBZ24435.1 - 0.0026 18.1 0.1 0.0063 16.9 0.1 1.8 1 1 0 1 1 1 1 AAA ATPase domain PduV-EutP PF10662.9 CBZ24435.1 - 0.0042 16.8 0.0 0.014 15.1 0.0 1.8 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation ATP_bind_1 PF03029.17 CBZ24435.1 - 0.0048 16.7 0.2 0.36 10.6 0.0 2.1 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein AAA_33 PF13671.6 CBZ24435.1 - 0.0092 16.1 0.0 0.021 15.0 0.0 1.6 1 1 0 1 1 1 1 AAA domain SRPRB PF09439.10 CBZ24435.1 - 0.018 14.5 0.0 0.027 13.9 0.0 1.6 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit ABC_tran PF00005.27 CBZ24435.1 - 0.027 15.0 0.1 0.1 13.1 0.1 2.0 1 1 0 1 1 1 0 ABC transporter IIGP PF05049.13 CBZ24435.1 - 0.029 13.4 0.0 0.18 10.8 0.0 2.0 2 0 0 2 2 2 0 Interferon-inducible GTPase (IIGP) Gp-FAR-1 PF05823.12 CBZ24435.1 - 0.037 14.4 0.9 0.057 13.8 0.9 1.2 1 0 0 1 1 1 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) RNA_helicase PF00910.22 CBZ24435.1 - 0.059 13.8 0.0 0.22 11.9 0.0 1.9 2 0 0 2 2 2 0 RNA helicase Septin PF00735.18 CBZ24435.1 - 0.067 12.5 0.1 0.15 11.3 0.0 1.5 2 0 0 2 2 2 0 Septin AAA_22 PF13401.6 CBZ24435.1 - 0.094 13.0 0.0 0.58 10.4 0.0 2.1 2 1 0 2 2 2 0 AAA domain DUF87 PF01935.17 CBZ24435.1 - 0.14 12.3 0.2 3.7 7.6 0.0 2.1 2 0 0 2 2 2 0 Helicase HerA, central domain Ras PF00071.22 CBZ24436.1 - 6.4e-45 152.6 0.0 7.5e-45 152.4 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CBZ24436.1 - 5.5e-26 91.1 0.0 8.7e-26 90.5 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CBZ24436.1 - 7.8e-07 28.7 0.0 9.4e-07 28.4 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 CBZ24436.1 - 1.6e-05 24.5 0.0 0.00033 20.2 0.0 2.1 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 CBZ24436.1 - 0.00011 21.6 0.0 0.00013 21.4 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 CBZ24436.1 - 0.027 14.6 0.0 0.051 13.7 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase PrgI PF12666.7 CBZ24437.1 - 0.015 16.0 3.7 0.023 15.4 0.9 2.0 2 0 0 2 2 2 0 PrgI family protein DUF4131 PF13567.6 CBZ24437.1 - 0.95 9.1 6.0 0.23 11.1 1.8 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4131) RIB43A PF05914.12 CBZ24438.1 - 2.2e-74 250.5 65.2 2.6e-74 250.2 65.2 1.0 1 0 0 1 1 1 1 RIB43A zf-RanBP PF00641.18 CBZ24439.1 - 3.2e-09 36.0 25.1 0.0013 18.0 5.9 3.6 3 0 0 3 3 3 3 Zn-finger in Ran binding protein and others DZR PF12773.7 CBZ24439.1 - 1.3e-06 28.3 17.5 0.0013 18.7 9.6 2.7 1 1 1 2 2 2 2 Double zinc ribbon Ima1_N PF09779.9 CBZ24439.1 - 0.13 13.1 0.2 0.13 13.1 0.2 3.4 3 1 0 3 3 3 0 Ima1 N-terminal domain Atx10homo_assoc PF09759.9 CBZ24442.1 - 6.1e-23 80.7 0.0 1.1e-22 79.9 0.0 1.5 1 0 0 1 1 1 1 Spinocerebellar ataxia type 10 protein domain Methyltransf_23 PF13489.6 CBZ24445.1 - 1.2e-19 70.8 0.0 1.6e-19 70.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CBZ24445.1 - 8e-06 26.4 0.1 0.0003 21.4 0.0 2.5 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 CBZ24445.1 - 1.7e-05 25.5 0.0 0.00067 20.4 0.0 2.3 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 CBZ24445.1 - 0.0018 18.9 0.0 0.69 10.7 0.0 2.6 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 CBZ24445.1 - 0.02 14.7 0.0 0.23 11.3 0.0 2.1 1 1 1 2 2 2 0 Methyltransferase domain c-SKI_SMAD_bind PF08782.10 CBZ24445.1 - 0.12 12.6 0.9 0.47 10.7 0.9 2.0 1 1 0 1 1 1 0 c-SKI Smad4 binding domain Ubie_methyltran PF01209.18 CBZ24445.1 - 0.15 11.4 0.0 0.57 9.5 0.0 1.7 1 1 1 2 2 2 0 ubiE/COQ5 methyltransferase family DUF1861 PF08950.10 CBZ24446.1 - 7.7e-120 399.6 0.1 8.9e-120 399.4 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1861) DUF1861 PF08950.10 CBZ24447.1 - 4.7e-118 393.7 0.0 5.4e-118 393.5 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1861) DUF1861 PF08950.10 CBZ24448.1 - 4.9e-121 403.5 0.0 5.8e-121 403.3 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1861) DUF1861 PF08950.10 CBZ24449.1 - 5.5e-121 403.4 0.0 6.4e-121 403.2 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1861) Herpeto_peptide PF14409.6 CBZ24449.1 - 0.14 12.5 0.0 1.3 9.3 0.0 2.4 2 0 0 2 2 2 0 Ribosomally synthesized peptide in Herpetosiphon DUF1861 PF08950.10 CBZ24450.1 - 2.2e-116 388.3 0.0 2.5e-116 388.1 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1861) DUF5565 PF17720.1 CBZ24450.1 - 0.18 10.6 0.0 0.27 10.0 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5565) DUF1861 PF08950.10 CBZ24451.1 - 4.3e-121 403.7 0.0 5e-121 403.5 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1861) DUF1861 PF08950.10 CBZ24452.1 - 2.5e-118 394.6 0.0 2.9e-118 394.4 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1861) Ada_Zn_binding PF02805.16 CBZ24452.1 - 0.17 11.9 0.1 0.4 10.7 0.1 1.6 1 0 0 1 1 1 0 Metal binding domain of Ada PHO4 PF01384.20 CBZ24453.1 - 8.7e-111 370.2 19.1 1.1e-110 369.9 19.1 1.1 1 0 0 1 1 1 1 Phosphate transporter family CENP_C_N PF15622.6 CBZ24453.1 - 0.12 11.8 0.5 0.18 11.3 0.5 1.1 1 0 0 1 1 1 0 Kinetochore assembly subunit CENP-C N-terminal HECW_N PF16562.5 CBZ24453.1 - 0.18 11.6 0.0 0.32 10.8 0.0 1.3 1 0 0 1 1 1 0 N-terminal domain of E3 ubiquitin-protein ligase HECW1 and 2 BT1 PF03092.16 CBZ24454.1 - 9.3e-195 647.8 12.9 1.1e-194 647.5 12.9 1.0 1 0 0 1 1 1 1 BT1 family FA_desaturase PF00487.24 CBZ24455.1 - 9.4e-28 97.7 26.1 9.4e-28 97.7 26.1 1.9 1 1 1 2 2 2 1 Fatty acid desaturase GIT_CC PF16559.5 CBZ24456.1 - 0.0034 17.2 1.4 0.03 14.2 0.8 2.4 1 1 1 2 2 2 1 GIT coiled-coil Rho guanine nucleotide exchange factor TipAS PF07739.13 CBZ24456.1 - 0.0045 17.5 1.1 0.0074 16.8 1.1 1.4 1 0 0 1 1 1 1 TipAS antibiotic-recognition domain KASH_CCD PF14662.6 CBZ24456.1 - 0.016 15.0 14.4 0.028 14.2 14.4 1.4 1 1 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH Strep_SA_rep PF06696.11 CBZ24456.1 - 0.018 15.1 0.1 0.046 13.7 0.1 1.7 1 0 0 1 1 1 0 Streptococcal surface antigen repeat DUF3450 PF11932.8 CBZ24456.1 - 0.018 14.3 3.0 0.03 13.6 2.8 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3450) CENP-H PF05837.12 CBZ24456.1 - 0.026 14.9 6.5 0.026 14.9 6.5 1.8 1 1 1 2 2 2 0 Centromere protein H (CENP-H) CENP-F_leu_zip PF10473.9 CBZ24456.1 - 0.072 13.1 13.4 0.083 12.9 4.8 2.2 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Shugoshin_N PF07558.11 CBZ24456.1 - 0.16 11.8 4.7 0.68 9.9 1.2 2.6 1 1 1 2 2 2 0 Shugoshin N-terminal coiled-coil region RF-1 PF00472.20 CBZ24456.1 - 0.2 11.6 4.2 0.31 11.0 4.1 1.5 1 1 0 1 1 1 0 RF-1 domain TRAF_BIRC3_bd PF16673.5 CBZ24456.1 - 0.35 10.7 8.4 0.44 10.4 5.0 2.5 2 0 0 2 2 2 0 TNF receptor-associated factor BIRC3 binding domain GAS PF13851.6 CBZ24456.1 - 0.38 10.1 11.9 2.7 7.3 11.8 2.1 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding V_ATPase_I PF01496.19 CBZ24456.1 - 0.73 7.7 7.1 0.85 7.5 7.1 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family TMF_DNA_bd PF12329.8 CBZ24456.1 - 0.8 9.7 13.3 2.4 8.2 5.7 3.1 2 1 1 3 3 3 0 TATA element modulatory factor 1 DNA binding DUF4200 PF13863.6 CBZ24456.1 - 2.4 8.6 14.0 0.96 9.9 10.0 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) ERM PF00769.19 CBZ24456.1 - 2.5 7.8 17.8 5 6.9 16.0 1.8 1 1 1 2 2 2 0 Ezrin/radixin/moesin family YabA PF06156.13 CBZ24456.1 - 3.2 8.4 9.0 17 6.1 8.4 2.3 1 1 1 2 2 2 0 Initiation control protein YabA COPIIcoated_ERV PF07970.12 CBZ24457.1 - 1.3e-36 126.5 0.0 1.9e-36 126.0 0.0 1.2 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.6 CBZ24457.1 - 2.1e-18 66.5 0.0 3.9e-18 65.6 0.0 1.5 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) Hexapep PF00132.24 CBZ24458.1 - 5.1e-12 45.0 2.6 5.3e-05 22.8 0.1 3.3 3 0 0 3 3 3 3 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 CBZ24458.1 - 0.031 14.0 3.0 13 5.6 0.2 3.3 2 1 1 3 3 3 0 Hexapeptide repeat of succinyl-transferase ABC_tran PF00005.27 CBZ24459.1 - 6.7e-28 97.9 0.1 1.4e-27 96.9 0.0 1.5 2 0 0 2 2 2 1 ABC transporter AAA_21 PF13304.6 CBZ24459.1 - 0.00075 19.4 0.8 0.19 11.5 0.1 2.3 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 CBZ24459.1 - 0.0024 17.3 0.3 0.031 13.7 0.0 2.1 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 CBZ24459.1 - 0.0035 17.1 0.1 0.0079 15.9 0.1 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 CBZ24459.1 - 0.0052 16.7 0.5 0.016 15.1 0.1 1.9 2 0 0 2 2 2 1 RsgA GTPase AAA_16 PF13191.6 CBZ24459.1 - 0.033 14.6 0.1 0.065 13.6 0.1 1.6 1 1 0 1 1 1 0 AAA ATPase domain AAA_23 PF13476.6 CBZ24459.1 - 0.1 13.1 0.2 0.38 11.2 0.0 1.8 2 0 0 2 2 2 0 AAA domain KDGP_aldolase PF07071.11 CBZ24459.1 - 0.15 11.8 0.0 0.22 11.3 0.0 1.2 1 0 0 1 1 1 0 KDGP aldolase SbcCD_C PF13558.6 CBZ24459.1 - 1 9.6 4.2 1.5 9.1 0.1 2.9 3 1 0 3 3 3 0 Putative exonuclease SbcCD, C subunit SNF2_N PF00176.23 CBZ24460.1 - 3.7e-25 88.4 0.0 5.9e-25 87.7 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain HNH PF01844.23 CBZ24460.1 - 6.4e-08 32.7 0.4 6.4e-08 32.7 0.4 2.9 2 0 0 2 2 2 1 HNH endonuclease Helicase_C PF00271.31 CBZ24460.1 - 1.7e-05 25.1 0.0 3.6e-05 24.1 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 CBZ24460.1 - 0.0002 21.4 0.0 0.00069 19.7 0.0 1.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit HNH_5 PF14279.6 CBZ24460.1 - 0.0008 19.2 0.1 0.0008 19.2 0.1 2.2 2 0 0 2 2 2 1 HNH endonuclease zf-RING_10 PF16685.5 CBZ24460.1 - 0.073 13.2 0.2 0.073 13.2 0.2 2.3 2 0 0 2 2 2 0 zinc RING finger of MSL2 Tenui_NS3 PF05310.12 CBZ24460.1 - 0.11 12.6 0.1 0.21 11.7 0.1 1.4 1 0 0 1 1 1 0 Tenuivirus movement protein Pkinase PF00069.25 CBZ24461.1 - 2.5e-41 141.8 0.0 1.6e-26 93.2 0.0 2.6 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ24461.1 - 4.9e-16 58.8 0.2 1.6e-08 34.2 0.2 3.2 2 1 0 2 2 2 2 Protein tyrosine kinase APH PF01636.23 CBZ24461.1 - 0.012 15.6 0.0 0.025 14.5 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family FTA2 PF13095.6 CBZ24461.1 - 0.019 14.6 0.1 0.92 9.1 0.0 2.4 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 NCD1 PF04904.13 CBZ24461.1 - 0.026 14.5 0.1 0.14 12.2 0.0 2.1 2 0 0 2 2 2 0 NAB conserved region 1 (NCD1) PI3K_1B_p101 PF10486.9 CBZ24461.1 - 0.026 12.3 7.1 0.041 11.7 7.1 1.2 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit GRIP PF01465.20 CBZ24462.1 - 1e-11 44.5 0.0 2.6e-11 43.3 0.0 1.8 1 0 0 1 1 1 1 GRIP domain eIF3m_C_helix PF18005.1 CBZ24462.1 - 1.6e-05 24.5 11.7 10 5.9 0.1 7.0 6 0 0 6 6 6 2 eIF3 subunit M, C-terminal helix Cep57_CLD_2 PF14197.6 CBZ24462.1 - 0.0053 16.8 271.7 0.12 12.5 10.3 18.3 10 4 8 19 19 19 11 Centrosome localisation domain of PPC89 DUF3240 PF11582.8 CBZ24462.1 - 0.19 11.9 21.3 8.5 6.6 0.9 6.4 4 0 0 4 4 4 0 Protein of unknown function (DUF3240) Pox_A_type_inc PF04508.12 CBZ24462.1 - 1 9.3 9.1 0.82 9.6 0.2 5.4 4 0 0 4 4 4 0 Viral A-type inclusion protein repeat Erp_C PF06780.11 CBZ24462.1 - 4.1 7.4 8.6 3 7.9 0.8 4.5 4 0 0 4 4 4 0 Erp protein C-terminus RRM_1 PF00076.22 CBZ24463.1 - 1.3e-05 24.9 0.1 7.1e-05 22.6 0.1 2.2 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF4636 PF15468.6 CBZ24463.1 - 0.00065 19.5 2.1 0.0014 18.4 0.1 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4636) MORN PF02493.20 CBZ24464.1 - 1.5e-22 78.1 29.3 9e-07 28.4 0.6 6.4 6 0 0 6 6 6 6 MORN repeat tRNA-synt_2b PF00587.25 CBZ24465.1 - 4.1e-32 111.6 0.0 8.3e-32 110.6 0.0 1.5 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.22 CBZ24465.1 - 3.7e-14 52.8 5.1 1.8e-13 50.7 0.6 2.3 1 1 0 2 2 2 2 Seryl-tRNA synthetase N-terminal domain Pkinase PF00069.25 CBZ24466.1 - 6.6e-51 173.2 0.0 8.5e-51 172.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ24466.1 - 9.9e-27 93.8 0.0 1.4e-26 93.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CBZ24466.1 - 4.5e-09 36.0 0.0 9.2e-09 35.0 0.0 1.5 1 1 0 1 1 1 1 Kinase-like APH PF01636.23 CBZ24466.1 - 0.00011 22.3 0.3 0.00052 20.0 0.2 1.9 1 1 1 2 2 2 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 CBZ24466.1 - 0.00065 18.7 0.0 0.001 18.1 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Seadorna_VP7 PF07387.11 CBZ24466.1 - 0.0028 16.8 0.2 0.0043 16.1 0.2 1.2 1 0 0 1 1 1 1 Seadornavirus VP7 Kdo PF06293.14 CBZ24466.1 - 0.0036 16.7 0.1 0.0076 15.6 0.1 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 CBZ24466.1 - 0.018 14.6 0.0 0.033 13.8 0.0 1.3 1 0 0 1 1 1 0 RIO1 family GPHH PF16905.5 CBZ24466.1 - 0.074 12.8 0.0 0.18 11.6 0.0 1.6 1 0 0 1 1 1 0 Voltage-dependent L-type calcium channel, IQ-associated PAC1 PF16094.5 CBZ24466.1 - 0.088 12.0 0.0 0.13 11.4 0.0 1.1 1 0 0 1 1 1 0 Proteasome assembly chaperone 4 Choline_kinase PF01633.20 CBZ24466.1 - 0.18 11.4 0.0 0.26 10.9 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase NIF3 PF01784.18 CBZ24468.1 - 1.2e-68 231.4 0.0 1.4e-68 231.1 0.0 1.0 1 0 0 1 1 1 1 NIF3 (NGG1p interacting factor 3) PSP1 PF04468.12 CBZ24469.1 - 3.4e-28 97.8 0.2 5.5e-28 97.1 0.2 1.3 1 0 0 1 1 1 1 PSP1 C-terminal conserved region RAP1 PF07218.11 CBZ24470.1 - 0.3 9.3 10.2 0.4 8.9 10.2 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Tmemb_cc2 PF10267.9 CBZ24470.1 - 8.1 5.5 12.0 13 4.8 12.0 1.2 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein 3-PAP PF12578.8 CBZ24472.1 - 2.2e-18 66.3 0.5 2.2e-18 66.3 0.5 2.2 2 0 0 2 2 2 1 Myotubularin-associated protein Dzip-like_N PF13815.6 CBZ24472.1 - 0.0022 18.0 0.3 0.0022 18.0 0.3 3.1 2 1 1 3 3 3 1 Iguana/Dzip1-like DAZ-interacting protein N-terminal ATG16 PF08614.11 CBZ24472.1 - 0.005 17.1 5.7 0.005 17.1 5.7 3.6 4 1 0 4 4 4 1 Autophagy protein 16 (ATG16) eIF-4B PF06273.11 CBZ24472.1 - 0.014 14.5 1.4 0.047 12.7 0.3 2.0 2 0 0 2 2 2 0 Plant specific eukaryotic initiation factor 4B DUF812 PF05667.11 CBZ24472.1 - 0.62 8.9 8.1 4.2 6.1 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF812) HAUS-augmin3 PF14932.6 CBZ24472.1 - 8.9 5.8 18.1 5.2 6.6 7.4 2.4 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 3 Pre-PUA PF17832.1 CBZ24473.1 - 6.4e-20 71.6 0.2 9.8e-20 71.1 0.2 1.3 1 0 0 1 1 1 1 Pre-PUA-like domain PUA PF01472.20 CBZ24473.1 - 1.2e-15 57.2 1.3 2e-15 56.5 1.3 1.4 1 0 0 1 1 1 1 PUA domain DUF1947 PF09183.10 CBZ24473.1 - 0.0099 16.2 1.3 0.23 11.8 0.5 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF1947) FumaraseC_C PF10415.9 CBZ24473.1 - 0.11 12.9 0.7 0.19 12.2 0.2 1.6 2 0 0 2 2 2 0 Fumarase C C-terminus DEAD PF00270.29 CBZ24474.1 - 3e-23 82.5 0.0 5.3e-23 81.7 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 CBZ24474.1 - 4.4e-07 30.1 0.0 8.6e-07 29.1 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 CBZ24474.1 - 3.3e-06 27.4 0.2 1.3e-05 25.5 0.1 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain Pyrophosphatase PF00719.19 CBZ24476.1 - 1.4e-46 158.3 0.1 2.4e-46 157.5 0.1 1.4 1 0 0 1 1 1 1 Inorganic pyrophosphatase EF-hand_7 PF13499.6 CBZ24476.1 - 0.0011 19.3 0.1 0.0071 16.8 0.0 2.4 3 0 0 3 3 3 1 EF-hand domain pair Pterin_4a PF01329.19 CBZ24477.1 - 9.4e-29 99.4 0.1 1.1e-28 99.2 0.1 1.0 1 0 0 1 1 1 1 Pterin 4 alpha carbinolamine dehydratase FYRC PF05965.14 CBZ24477.1 - 0.051 13.7 0.0 2.7 8.2 0.0 2.2 2 0 0 2 2 2 0 F/Y rich C-terminus Rad51 PF08423.11 CBZ24478.1 - 1.9e-19 69.9 0.0 3.8e-19 68.9 0.0 1.4 1 1 0 1 1 1 1 Rad51 AAA_25 PF13481.6 CBZ24478.1 - 1.9e-08 34.1 1.1 4.1e-08 33.0 1.1 1.6 1 0 0 1 1 1 1 AAA domain ATPase PF06745.13 CBZ24478.1 - 1.6e-06 27.7 0.0 9.9e-06 25.1 0.0 1.9 2 0 0 2 2 2 1 KaiC DnaB_C PF03796.15 CBZ24478.1 - 1.7e-06 27.6 0.1 0.049 13.0 0.1 2.1 2 0 0 2 2 2 2 DnaB-like helicase C terminal domain AAA PF00004.29 CBZ24478.1 - 5e-05 23.7 0.0 0.00018 21.9 0.0 1.8 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 CBZ24478.1 - 0.00095 19.6 0.5 0.0019 18.6 0.5 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_33 PF13671.6 CBZ24478.1 - 0.0099 16.0 0.8 0.04 14.1 0.8 2.2 1 1 0 1 1 1 1 AAA domain RecA PF00154.21 CBZ24478.1 - 0.014 14.8 0.1 0.039 13.4 0.0 1.6 2 0 0 2 2 2 0 recA bacterial DNA recombination protein AAA_22 PF13401.6 CBZ24478.1 - 0.026 14.8 0.1 0.055 13.7 0.1 1.5 1 1 0 1 1 1 0 AAA domain AAA_18 PF13238.6 CBZ24478.1 - 0.086 13.4 0.2 0.18 12.4 0.2 1.6 1 1 0 1 1 1 0 AAA domain AAA_30 PF13604.6 CBZ24478.1 - 0.14 11.8 0.4 0.27 10.9 0.0 1.7 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.15 CBZ24478.1 - 0.32 10.9 0.2 1.4 8.8 0.2 1.9 1 1 0 1 1 1 0 NTPase Proteasome PF00227.26 CBZ24479.1 - 2.7e-58 196.6 0.1 3.8e-58 196.1 0.1 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 CBZ24479.1 - 1.4e-14 53.4 0.2 2.7e-14 52.5 0.2 1.5 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Styelin PF17562.2 CBZ24479.1 - 0.015 15.6 4.1 0.049 14.0 1.9 2.3 2 0 0 2 2 2 0 Styelin DUF365 PF04033.12 CBZ24479.1 - 0.051 13.9 0.6 0.11 12.8 0.6 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF365) Pkinase PF00069.25 CBZ24480.1 - 5.2e-46 157.1 0.0 2.4e-34 118.9 0.0 3.3 3 0 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ24480.1 - 7.6e-29 100.8 0.0 2.2e-23 82.9 0.0 3.3 2 1 1 3 3 3 3 Protein tyrosine kinase Kinase-like PF14531.6 CBZ24480.1 - 9.4e-06 25.1 0.0 0.014 14.7 0.0 2.2 2 0 0 2 2 2 2 Kinase-like Pkinase_fungal PF17667.1 CBZ24480.1 - 1.4e-05 24.1 0.8 3.4e-05 22.8 0.0 2.0 2 0 0 2 2 2 1 Fungal protein kinase APH PF01636.23 CBZ24480.1 - 0.057 13.3 2.6 0.066 13.1 0.1 2.2 2 1 1 3 3 3 0 Phosphotransferase enzyme family PEPCK_ATP PF01293.20 CBZ24481.1 - 0.0025 16.6 0.0 0.0036 16.0 0.0 1.1 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase CtsR_C PF17727.1 CBZ24481.1 - 0.15 12.2 0.0 0.31 11.2 0.0 1.4 1 0 0 1 1 1 0 CtsR C-terminal dimerization domain FAD_binding_6 PF00970.24 CBZ24482.1 - 3.8e-09 36.8 0.0 1.1e-08 35.4 0.0 1.7 2 0 0 2 2 2 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.21 CBZ24482.1 - 0.0017 19.0 0.0 0.005 17.5 0.0 1.8 1 1 0 1 1 1 1 Oxidoreductase NAD-binding domain DUF3042 PF11240.8 CBZ24482.1 - 0.14 12.2 0.0 0.35 10.9 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3042) DUF5327 PF17261.2 CBZ24483.1 - 1.5 9.6 3.4 6.2 7.6 3.4 2.0 1 0 0 1 1 1 0 Family of unknown function (DUF5327) CCDC74_C PF14917.6 CBZ24484.1 - 0.093 13.3 2.8 0.22 12.0 0.2 2.7 3 0 0 3 3 3 0 Coiled coil protein 74, C terminal Sec20 PF03908.13 CBZ24485.1 - 1.7e-08 34.3 2.9 1.7e-08 34.3 2.9 2.0 2 1 0 2 2 2 1 Sec20 TEX13 PF15186.6 CBZ24485.1 - 0.024 14.3 1.9 0.024 14.3 1.9 2.3 2 1 1 3 3 3 0 Testis-expressed sequence 13 protein family Sec34 PF04136.15 CBZ24485.1 - 0.12 12.3 4.6 4.1 7.3 0.5 2.3 2 0 0 2 2 2 0 Sec34-like family DUF4471 PF14740.6 CBZ24485.1 - 0.14 11.3 0.7 0.17 11.1 0.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4471) DHR10 PF18595.1 CBZ24485.1 - 0.23 11.6 0.0 0.23 11.6 0.0 2.9 3 0 0 3 3 3 0 Designed helical repeat protein 10 domain HalX PF08663.10 CBZ24485.1 - 0.31 11.4 7.6 0.24 11.7 0.7 3.4 3 1 0 3 3 3 0 HalX domain HisKA PF00512.25 CBZ24485.1 - 0.82 9.7 5.2 3.3 7.8 0.4 2.9 2 1 0 2 2 2 0 His Kinase A (phospho-acceptor) domain Prefoldin_2 PF01920.20 CBZ24485.1 - 2.1 8.4 6.8 1.5 8.8 0.2 2.8 3 1 0 3 3 3 0 Prefoldin subunit Stonin2_N PF12016.8 CBZ24486.1 - 0.82 9.0 8.9 1.5 8.1 1.7 2.7 1 1 1 2 2 2 0 Stonin 2 PIF1 PF05970.14 CBZ24487.1 - 1.4e-30 106.7 0.8 9e-24 84.3 0.9 3.5 3 1 0 3 3 3 3 PIF1-like helicase AAA_30 PF13604.6 CBZ24487.1 - 9.4e-22 77.7 0.0 1.9e-21 76.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 CBZ24487.1 - 6.5e-06 26.6 1.3 2.1e-05 24.9 0.3 2.4 2 1 0 2 2 2 1 AAA domain DUF853 PF05872.12 CBZ24487.1 - 0.00038 19.2 1.4 0.00075 18.2 1.4 1.4 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF853) AAA_22 PF13401.6 CBZ24487.1 - 0.0022 18.3 1.2 3.3 8.0 0.3 2.9 2 0 0 2 2 2 2 AAA domain Herpes_Helicase PF02689.14 CBZ24487.1 - 0.003 15.6 0.1 0.84 7.5 0.0 2.6 3 0 0 3 3 3 2 Helicase UvrD_C_2 PF13538.6 CBZ24487.1 - 0.018 14.9 0.4 0.12 12.2 0.4 2.4 1 1 0 1 1 1 0 UvrD-like helicase C-terminal domain AAA_16 PF13191.6 CBZ24487.1 - 0.041 14.3 0.3 0.041 14.3 0.3 3.4 3 0 0 3 3 3 0 AAA ATPase domain RsgA_GTPase PF03193.16 CBZ24487.1 - 0.1 12.5 0.2 0.21 11.5 0.2 1.4 1 0 0 1 1 1 0 RsgA GTPase AAA_7 PF12775.7 CBZ24487.1 - 0.16 11.5 0.0 0.31 10.5 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region Viral_helicase1 PF01443.18 CBZ24487.1 - 0.17 11.6 0.1 12 5.5 0.0 2.8 2 1 0 2 2 2 0 Viral (Superfamily 1) RNA helicase ABC_tran PF00005.27 CBZ24487.1 - 0.21 12.1 0.4 0.66 10.5 0.4 1.8 1 0 0 1 1 1 0 ABC transporter PIF1 PF05970.14 CBZ24488.1 - 7.1e-36 124.1 0.4 3e-28 99.0 0.1 3.4 2 1 1 3 3 3 3 PIF1-like helicase AAA_30 PF13604.6 CBZ24488.1 - 8.1e-17 61.6 0.9 2.4e-16 60.0 0.0 2.3 3 0 0 3 3 2 1 AAA domain AAA_19 PF13245.6 CBZ24488.1 - 5.7e-06 26.7 0.1 2.1e-05 24.9 0.1 2.0 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 CBZ24488.1 - 0.0024 18.3 0.1 0.011 16.2 0.1 2.2 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 CBZ24488.1 - 0.0031 17.8 0.7 0.11 12.8 0.7 2.6 1 1 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 CBZ24488.1 - 0.0037 16.7 0.2 0.011 15.2 0.2 1.7 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA PF00004.29 CBZ24488.1 - 0.0046 17.4 0.0 0.012 16.1 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Viral_helicase1 PF01443.18 CBZ24488.1 - 0.0052 16.6 0.1 5 6.8 0.0 2.9 2 1 0 2 2 2 2 Viral (Superfamily 1) RNA helicase AAA_5 PF07728.14 CBZ24488.1 - 0.0053 16.8 0.0 0.019 15.0 0.0 2.0 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_11 PF13086.6 CBZ24488.1 - 0.0092 15.8 0.1 0.057 13.2 0.0 2.3 1 1 0 2 2 2 1 AAA domain UvrD_C_2 PF13538.6 CBZ24488.1 - 0.014 15.2 0.4 0.095 12.5 0.4 2.3 1 1 0 1 1 1 0 UvrD-like helicase C-terminal domain Herpes_Helicase PF02689.14 CBZ24488.1 - 0.024 12.6 0.2 0.17 9.8 0.0 2.0 2 0 0 2 2 2 0 Helicase FtsK_SpoIIIE PF01580.18 CBZ24488.1 - 0.063 12.6 0.2 12 5.1 0.0 2.6 2 0 0 2 2 2 0 FtsK/SpoIIIE family DUF853 PF05872.12 CBZ24488.1 - 0.071 11.7 0.3 0.14 10.7 0.3 1.4 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) PhoH PF02562.16 CBZ24488.1 - 0.074 12.5 0.1 0.21 11.0 0.1 1.8 1 0 0 1 1 1 0 PhoH-like protein mTERF PF02536.14 CBZ24488.1 - 0.093 11.6 0.0 0.15 10.9 0.0 1.2 1 0 0 1 1 1 0 mTERF NACHT PF05729.12 CBZ24488.1 - 0.15 12.0 0.1 0.3 11.0 0.1 1.5 1 0 0 1 1 1 0 NACHT domain NTPase_1 PF03266.15 CBZ24488.1 - 0.4 10.6 1.5 1.8 8.4 0.2 2.2 2 0 0 2 2 2 0 NTPase 14-3-3 PF00244.20 CBZ24490.1 - 2.2e-82 275.9 3.1 2.5e-82 275.7 3.1 1.0 1 0 0 1 1 1 1 14-3-3 protein TPR_8 PF13181.6 CBZ24490.1 - 3.2 8.2 5.9 25 5.4 0.0 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat OPA3 PF07047.12 CBZ24491.1 - 2.1e-19 69.5 3.3 1.6e-18 66.7 3.3 2.1 1 1 0 1 1 1 1 Optic atrophy 3 protein (OPA3) Sporozoite_P67 PF05642.11 CBZ24491.1 - 0.27 9.3 9.5 0.41 8.7 9.5 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Herpes_UL25 PF01499.16 CBZ24491.1 - 0.66 8.4 0.0 0.66 8.4 0.0 2.0 2 0 0 2 2 2 0 Herpesvirus UL25 family Med3 PF11593.8 CBZ24491.1 - 3.6 6.7 16.2 5.4 6.1 16.2 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal DUF2779 PF11074.8 CBZ24493.1 - 2e-39 134.9 0.0 3.8e-39 134.0 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function(DUF2779) DNA_pol_B_2 PF03175.13 CBZ24493.1 - 0.09 11.6 0.1 0.16 10.8 0.1 1.2 1 0 0 1 1 1 0 DNA polymerase type B, organellar and viral DUF3450 PF11932.8 CBZ24493.1 - 7.7 5.7 10.8 16 4.7 10.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) TTL PF03133.15 CBZ24495.1 - 4.1e-68 229.6 0.1 6.4e-68 229.0 0.1 1.2 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 CBZ24495.1 - 4.4e-08 32.7 0.1 0.00022 20.6 0.0 3.2 2 1 1 3 3 3 2 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 CBZ24495.1 - 4.4e-05 22.9 0.0 0.026 13.8 0.0 2.5 2 1 0 2 2 2 2 Sugar-transfer associated ATP-grasp ATP-grasp_3 PF02655.14 CBZ24495.1 - 0.068 13.2 0.0 0.19 11.8 0.0 1.7 2 0 0 2 2 2 0 ATP-grasp domain KfrA_N PF11740.8 CBZ24495.1 - 0.13 13.0 2.4 0.23 12.2 0.2 2.4 2 0 0 2 2 2 0 Plasmid replication region DNA-binding N-term Hanta_G1 PF01567.16 CBZ24495.1 - 1.2 7.8 5.0 4.8 5.8 0.2 2.1 2 0 0 2 2 2 0 Hantavirus glycoprotein G1 BOP1NT PF08145.12 CBZ24496.1 - 1.4e-78 264.4 8.0 2.3e-78 263.7 8.0 1.4 1 0 0 1 1 1 1 BOP1NT (NUC169) domain WD40 PF00400.32 CBZ24496.1 - 1e-17 64.1 3.7 1.6e-07 31.9 0.0 5.7 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBZ24496.1 - 9.9e-07 29.0 0.0 0.0015 18.8 0.0 4.1 3 1 2 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 CBZ24496.1 - 0.021 13.8 0.0 1.1 8.2 0.0 2.5 3 0 0 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein CDC27 PF09507.10 CBZ24496.1 - 1.9 7.8 9.5 0.42 9.9 5.6 1.8 2 0 0 2 2 2 0 DNA polymerase subunit Cdc27 RCC1 PF00415.18 CBZ24497.1 - 4.1e-26 91.3 13.5 1e-06 29.3 0.0 8.1 6 2 0 6 6 6 3 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 CBZ24497.1 - 9.3e-11 41.2 24.2 7.3e-07 28.8 0.4 6.0 7 0 0 7 7 7 3 Regulator of chromosome condensation (RCC1) repeat LRR_4 PF12799.7 CBZ24499.1 - 6.2e-15 55.1 16.7 3.6e-06 27.2 0.2 4.1 2 1 1 4 4 4 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CBZ24499.1 - 2.1e-11 43.4 21.2 3.1e-05 23.6 1.5 3.8 3 1 0 3 3 3 3 Leucine rich repeat LRR_6 PF13516.6 CBZ24499.1 - 3.8e-05 23.4 19.1 0.19 11.8 0.8 5.7 6 0 0 6 6 6 3 Leucine Rich repeat LRR_9 PF14580.6 CBZ24499.1 - 0.0026 17.3 4.0 0.12 11.9 1.5 2.6 2 1 1 3 3 3 2 Leucine-rich repeat TMF_TATA_bd PF12325.8 CBZ24499.1 - 0.11 12.7 2.3 0.37 11.0 2.3 1.8 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding DUF4407 PF14362.6 CBZ24499.1 - 0.21 10.9 4.3 0.36 10.1 4.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) LRR_1 PF00560.33 CBZ24499.1 - 0.69 10.7 23.6 21 6.2 0.1 6.9 5 1 1 6 6 6 0 Leucine Rich Repeat Metal_resist PF13801.6 CBZ24499.1 - 2.5 8.3 13.5 1.3 9.2 10.9 2.0 1 1 0 1 1 1 0 Heavy-metal resistance K_channel_TID PF07941.11 CBZ24499.1 - 8.8 6.9 14.2 2.9 8.4 9.2 2.4 2 0 0 2 2 2 0 Potassium channel Kv1.4 tandem inactivation domain DNA_ligase_OB_2 PF14743.6 CBZ24500.1 - 0.042 13.9 0.0 0.13 12.4 0.0 1.8 1 0 0 1 1 1 0 DNA ligase OB-like domain DNA_ligase_A_M PF01068.21 CBZ24500.1 - 0.11 12.1 0.0 11 5.6 0.0 2.9 4 0 0 4 4 4 0 ATP dependent DNA ligase domain PUF PF00806.19 CBZ24502.1 - 2.1e-09 36.5 0.0 2.3 8.1 0.0 5.8 5 0 0 5 5 5 5 Pumilio-family RNA binding repeat CPL PF08144.11 CBZ24502.1 - 0.093 13.1 9.3 0.18 12.1 0.1 5.0 5 2 2 7 7 7 0 CPL (NUC119) domain Pox_MCEL PF03291.16 CBZ24504.1 - 1.6e-14 53.8 0.0 2.7e-14 53.0 0.0 1.2 1 0 0 1 1 1 1 mRNA capping enzyme Methyltransf_25 PF13649.6 CBZ24504.1 - 2.8e-08 34.4 0.0 1e-06 29.4 0.0 2.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 CBZ24504.1 - 7.1e-06 26.6 0.0 0.00013 22.5 0.0 2.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 CBZ24504.1 - 5.5e-05 23.8 0.0 0.00016 22.3 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain NSP16 PF06460.12 CBZ24504.1 - 0.00094 18.4 0.1 0.0015 17.7 0.1 1.2 1 0 0 1 1 1 1 Coronavirus NSP16 Methyltransf_23 PF13489.6 CBZ24504.1 - 0.002 18.0 0.0 0.0044 16.9 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain PAM2 PF07145.15 CBZ24504.1 - 0.028 14.1 0.8 0.084 12.6 0.8 1.8 1 0 0 1 1 1 0 Ataxin-2 C-terminal region PHF5 PF03660.14 CBZ24504.1 - 0.089 13.0 1.1 0.26 11.5 1.1 1.7 1 0 0 1 1 1 0 PHF5-like protein TPMT PF05724.11 CBZ24504.1 - 0.14 11.8 0.0 0.35 10.5 0.0 1.6 1 0 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) zf-CHY PF05495.12 CBZ24504.1 - 0.36 11.4 6.1 0.83 10.2 6.1 1.6 1 0 0 1 1 1 0 CHY zinc finger TPR_1 PF00515.28 CBZ24505.1 - 2.7e-18 64.9 6.3 0.00014 21.6 0.2 6.4 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_2 PF07719.17 CBZ24505.1 - 1.4e-17 62.3 8.9 1.1e-05 25.2 0.0 6.7 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_11 PF13414.6 CBZ24505.1 - 5.1e-14 51.7 7.5 3.4e-06 26.6 0.0 5.3 4 1 1 5 5 5 3 TPR repeat TPR_12 PF13424.6 CBZ24505.1 - 1.2e-10 41.5 9.5 0.00034 20.9 0.2 4.7 4 1 1 5 5 4 3 Tetratricopeptide repeat TPR_16 PF13432.6 CBZ24505.1 - 7e-10 39.4 7.3 0.00071 20.2 0.1 4.8 4 2 0 5 5 4 2 Tetratricopeptide repeat TPR_8 PF13181.6 CBZ24505.1 - 2.6e-08 33.4 12.8 0.0024 17.9 0.5 6.3 7 0 0 7 7 6 2 Tetratricopeptide repeat TPR_7 PF13176.6 CBZ24505.1 - 4.4e-08 32.6 0.3 0.007 16.3 0.0 4.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.6 CBZ24505.1 - 2.3e-07 30.7 7.9 0.15 12.5 0.1 5.6 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_19 PF14559.6 CBZ24505.1 - 2.4e-05 24.8 10.3 1.1 9.9 0.1 4.9 4 2 0 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.6 CBZ24505.1 - 6.3e-05 23.5 8.8 0.21 12.5 0.0 5.3 4 1 1 5 5 3 2 Tetratricopeptide repeat TPR_MalT PF17874.1 CBZ24505.1 - 0.00011 21.8 0.9 0.87 8.9 0.0 3.3 3 0 0 3 3 3 2 MalT-like TPR region TPR_6 PF13174.6 CBZ24505.1 - 0.00014 22.3 1.7 9.1 7.2 0.0 5.4 5 0 0 5 5 5 1 Tetratricopeptide repeat ANAPC3 PF12895.7 CBZ24505.1 - 0.0059 16.8 2.0 0.27 11.5 0.1 3.2 3 0 0 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_10 PF13374.6 CBZ24505.1 - 0.0063 16.3 3.2 0.18 11.7 0.0 4.0 2 1 1 3 3 3 1 Tetratricopeptide repeat DUF3808 PF10300.9 CBZ24505.1 - 0.015 14.0 0.1 0.073 11.8 0.0 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF3808) Mei5 PF10376.9 CBZ24505.1 - 0.041 13.7 0.2 0.041 13.7 0.2 1.7 2 0 0 2 2 2 0 Double-strand recombination repair protein Sel1 PF08238.12 CBZ24505.1 - 0.15 12.8 4.1 23 5.9 1.4 4.4 3 1 0 3 3 3 0 Sel1 repeat MIT PF04212.18 CBZ24505.1 - 1 9.5 0.0 1 9.5 0.0 4.2 5 0 0 5 5 5 0 MIT (microtubule interacting and transport) domain Pkinase PF00069.25 CBZ24507.1 - 5.4e-31 107.9 0.0 1.2e-30 106.8 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ24507.1 - 1.4e-13 50.8 0.0 3.3e-11 43.0 0.0 2.4 2 1 0 2 2 2 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 CBZ24507.1 - 0.0012 17.7 0.0 0.0016 17.3 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Pox_ser-thr_kin PF05445.11 CBZ24507.1 - 0.0058 15.6 0.1 0.0087 15.1 0.1 1.1 1 0 0 1 1 1 1 Poxvirus serine/threonine protein kinase RIO1 PF01163.22 CBZ24507.1 - 0.017 14.7 0.0 0.036 13.7 0.0 1.5 1 0 0 1 1 1 0 RIO1 family APH PF01636.23 CBZ24507.1 - 0.11 12.4 0.0 0.18 11.7 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family AA_permease_2 PF13520.6 CBZ24508.1 - 1.9e-19 69.9 39.0 2.7e-19 69.3 39.0 1.2 1 0 0 1 1 1 1 Amino acid permease DUF563 PF04577.14 CBZ24510.1 - 1.6e-10 41.5 0.0 4.9e-10 39.9 0.0 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF563) Nucleoside_tran PF01733.18 CBZ24511.1 - 3.3e-32 112.1 16.1 4.3e-25 88.7 0.2 2.6 3 0 0 3 3 3 2 Nucleoside transporter Tex_N PF09371.10 CBZ24512.1 - 1e-38 132.8 0.3 2.7e-38 131.5 0.0 1.9 2 0 0 2 2 2 1 Tex-like protein N-terminal domain Tex_YqgF PF16921.5 CBZ24512.1 - 2e-32 112.3 0.1 5.6e-32 110.8 0.1 1.8 1 0 0 1 1 1 1 Tex protein YqgF-like domain HHH_9 PF17674.1 CBZ24512.1 - 1.7e-11 44.8 0.2 2.3e-09 38.0 0.2 3.3 1 1 0 1 1 1 1 HHH domain HHH_3 PF12836.7 CBZ24512.1 - 7.9e-10 38.9 0.1 1.5e-09 38.0 0.1 1.5 1 0 0 1 1 1 1 Helix-hairpin-helix motif YqgF PF14639.6 CBZ24512.1 - 9.1e-06 25.5 0.0 2e-05 24.4 0.0 1.6 1 0 0 1 1 1 1 Holliday-junction resolvase-like of SPT6 HHH_7 PF14635.6 CBZ24512.1 - 0.00023 21.5 0.0 0.00069 19.9 0.0 1.8 2 0 0 2 2 2 1 Helix-hairpin-helix motif S1 PF00575.23 CBZ24512.1 - 0.024 15.0 0.0 0.061 13.7 0.0 1.7 1 0 0 1 1 1 0 S1 RNA binding domain Cyt-b5 PF00173.28 CBZ24514.1 - 9.3e-20 70.6 0.0 1.5e-19 69.9 0.0 1.4 1 1 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain DUF4448 PF14610.6 CBZ24514.1 - 0.089 12.6 0.0 0.091 12.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) Carboxyl_trans PF01039.22 CBZ24515.1 - 1.3e-139 466.0 0.0 1.7e-139 465.7 0.0 1.1 1 0 0 1 1 1 1 Carboxyl transferase domain MdcE PF06833.11 CBZ24515.1 - 1e-06 28.4 0.1 0.029 13.9 0.0 2.3 2 0 0 2 2 2 2 Malonate decarboxylase gamma subunit (MdcE) ECH_1 PF00378.20 CBZ24515.1 - 2.1 7.6 8.4 3.6 6.8 0.2 3.4 4 0 0 4 4 4 0 Enoyl-CoA hydratase/isomerase Pns11_12 PF17464.2 CBZ24516.1 - 1.7 8.3 4.5 3.3 7.4 3.5 2.1 1 1 0 1 1 1 0 Non-structural protein 11 and 12 Peptidase_M17 PF00883.21 CBZ24518.1 - 1.4e-79 267.7 0.1 1.5e-79 267.5 0.1 1.0 1 0 0 1 1 1 1 Cytosol aminopeptidase family, catalytic domain 30K_MP_C_Ter PF11330.8 CBZ24518.1 - 0.13 11.5 0.0 0.21 10.9 0.0 1.2 1 0 0 1 1 1 0 C-Terminal of 30K viral movement proteins Peptidase_M17 PF00883.21 CBZ24519.1 - 3.7e-87 292.5 0.1 5.2e-87 292.0 0.1 1.2 1 0 0 1 1 1 1 Cytosol aminopeptidase family, catalytic domain Pdase_M17_N2 PF18295.1 CBZ24519.1 - 1.1e-30 106.4 2.8 1.1e-30 106.4 2.8 2.4 3 0 0 3 3 3 1 M17 aminopeptidase N-terminal domain 2 MFS_1 PF07690.16 CBZ24521.1 - 1.3e-21 76.9 26.8 6.3e-20 71.4 12.8 2.2 2 0 0 2 2 2 2 Major Facilitator Superfamily Nodulin-like PF06813.13 CBZ24521.1 - 1.1e-08 34.9 11.9 6.3e-08 32.4 11.9 2.2 1 1 0 1 1 1 1 Nodulin-like DUF996 PF06195.13 CBZ24521.1 - 0.28 11.5 0.1 0.28 11.5 0.1 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF996) SPC12 PF06645.13 CBZ24521.1 - 6.9 6.8 13.4 0.81 9.8 0.2 4.9 5 0 0 5 5 5 0 Microsomal signal peptidase 12 kDa subunit (SPC12) Nodulin-like PF06813.13 CBZ24522.1 - 4.2e-08 33.0 12.5 4.2e-08 33.0 12.5 2.5 2 2 0 2 2 2 1 Nodulin-like MotA_ExbB PF01618.16 CBZ24522.1 - 0.14 11.9 0.0 0.38 10.5 0.0 1.7 1 0 0 1 1 1 0 MotA/TolQ/ExbB proton channel family Nodulin-like PF06813.13 CBZ24523.1 - 5.6e-06 26.0 20.9 5.6e-06 26.0 20.9 3.5 2 2 1 3 3 3 1 Nodulin-like COX8 PF02285.15 CBZ24523.1 - 0.99 9.3 3.1 2.8 7.9 0.9 3.1 2 0 0 2 2 2 0 Cytochrome oxidase c subunit VIII DUF1129 PF06570.11 CBZ24523.1 - 1.4 8.4 12.5 2.3 7.6 0.1 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1129) MFS_1 PF07690.16 CBZ24524.1 - 0.00053 19.0 3.9 0.00059 18.9 3.9 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Ank_2 PF12796.7 CBZ24525.1 - 4.9e-24 84.7 1.5 3.3e-12 46.8 0.0 3.2 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CBZ24525.1 - 8.5e-23 80.4 3.8 9e-07 29.3 0.0 4.2 2 2 2 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.30 CBZ24525.1 - 2.7e-18 65.5 1.4 0.00061 20.1 0.0 5.0 5 0 0 5 5 5 4 Ankyrin repeat Ank_5 PF13857.6 CBZ24525.1 - 1.4e-17 63.5 4.5 8.3e-05 22.8 0.0 3.9 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 CBZ24525.1 - 1.5e-16 58.8 2.7 0.00046 20.4 0.0 5.4 5 0 0 5 5 5 3 Ankyrin repeat DpaA_N PF16924.5 CBZ24525.1 - 0.035 14.2 1.3 1.8 8.7 0.1 2.8 3 1 1 4 4 4 0 Dipicolinate synthase subunit A N-terminal domain DUF4829 PF16111.5 CBZ24525.1 - 0.094 13.5 0.0 0.2 12.4 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4829) ArsA_ATPase PF02374.15 CBZ24526.1 - 3.7e-88 295.6 0.1 3.9e-49 167.5 0.0 2.2 2 0 0 2 2 2 2 Anion-transporting ATPase AAA_31 PF13614.6 CBZ24526.1 - 7.4e-08 32.5 0.0 3.5e-07 30.3 0.0 2.0 1 1 0 1 1 1 1 AAA domain CbiA PF01656.23 CBZ24526.1 - 5.6e-07 29.7 0.0 3.4e-05 23.9 1.2 2.2 2 1 0 2 2 2 1 CobQ/CobB/MinD/ParA nucleotide binding domain ParA PF10609.9 CBZ24526.1 - 0.0072 15.8 0.1 0.031 13.7 0.1 1.9 2 0 0 2 2 2 1 NUBPL iron-transfer P-loop NTPase AAA_25 PF13481.6 CBZ24526.1 - 0.026 14.1 0.0 0.059 12.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain SRP54 PF00448.22 CBZ24526.1 - 0.058 13.0 0.2 2.7 7.6 0.2 2.5 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain Fer4_NifH PF00142.18 CBZ24526.1 - 0.16 11.4 0.0 0.83 9.0 0.0 2.0 2 0 0 2 2 2 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family Peptidase_C11 PF03415.14 CBZ24528.1 - 2e-07 30.7 0.0 2.8e-07 30.3 0.0 1.2 1 0 0 1 1 1 1 Clostripain family Ribosomal_S21e PF01249.18 CBZ24532.1 - 1.7e-33 114.5 0.1 2.2e-33 114.2 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein S21e Amelotin PF15757.5 CBZ24532.1 - 0.35 10.4 9.8 0.97 9.0 2.2 2.3 1 1 1 2 2 2 0 Amelotin Ribosomal_S21e PF01249.18 CBZ24533.1 - 1.5e-33 114.7 0.1 1.9e-33 114.4 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein S21e Amelotin PF15757.5 CBZ24533.1 - 0.96 9.0 7.6 0.74 9.4 1.6 2.2 1 1 1 2 2 2 0 Amelotin COX6B PF02297.17 CBZ24534.1 - 0.00089 19.4 8.2 0.19 12.0 0.8 2.9 1 1 2 3 3 3 2 Cytochrome oxidase c subunit VIb CX9C PF16860.5 CBZ24534.1 - 2.6 8.1 10.6 10 6.2 0.1 3.3 3 1 0 3 3 3 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, EF-hand_6 PF13405.6 CBZ24536.1 - 2e-14 52.2 0.0 0.11 12.5 0.0 7.3 8 0 0 8 8 8 4 EF-hand domain EF-hand_7 PF13499.6 CBZ24536.1 - 1.5e-11 44.6 0.0 0.33 11.4 0.0 6.0 6 0 0 6 6 6 4 EF-hand domain pair EF-hand_1 PF00036.32 CBZ24536.1 - 1.7e-06 27.2 0.0 3.9 7.2 0.0 5.7 6 0 0 6 6 6 2 EF hand EF-hand_8 PF13833.6 CBZ24536.1 - 0.0013 18.6 0.0 37 4.3 0.0 5.3 6 0 0 6 6 6 0 EF-hand domain pair EF-hand_11 PF08976.11 CBZ24536.1 - 0.059 14.3 0.0 9.2 7.2 0.0 3.9 4 0 0 4 4 4 0 EF-hand domain DUF3552 PF12072.8 CBZ24537.1 - 0.0002 20.9 12.8 0.00027 20.4 12.8 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3552) Jnk-SapK_ap_N PF09744.9 CBZ24537.1 - 0.022 15.0 12.1 0.036 14.3 12.1 1.3 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 APG6_N PF17675.1 CBZ24537.1 - 0.23 12.0 14.1 0.41 11.2 14.1 1.4 1 0 0 1 1 1 0 Apg6 coiled-coil region Hamartin PF04388.12 CBZ24537.1 - 1.7 7.2 16.4 2.1 6.9 16.4 1.1 1 0 0 1 1 1 0 Hamartin protein V_ATPase_I PF01496.19 CBZ24537.1 - 3.4 5.5 10.3 4.1 5.2 10.3 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family ALMT PF11744.8 CBZ24537.1 - 3.4 6.4 6.7 4.3 6.0 6.7 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter DUF3584 PF12128.8 CBZ24537.1 - 3.9 4.9 20.9 4.6 4.6 20.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Neur_chan_memb PF02932.16 CBZ24537.1 - 4 7.4 11.9 6.3 6.8 11.9 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region OmpH PF03938.14 CBZ24537.1 - 5.6 7.3 24.8 11 6.3 24.8 1.5 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Hid1 PF12722.7 CBZ24537.1 - 6.5 4.7 9.5 8.2 4.4 9.5 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DLIC PF05783.11 CBZ24537.1 - 7.2 5.3 7.4 10 4.8 7.4 1.2 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) LRS4 PF10422.9 CBZ24538.1 - 0.0042 16.7 7.1 0.012 15.2 7.1 1.7 1 0 0 1 1 1 1 Monopolin complex subunit LRS4 DUF2203 PF09969.9 CBZ24538.1 - 0.02 15.6 1.9 0.059 14.1 1.9 1.8 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) Sld5 PF05916.11 CBZ24538.1 - 0.096 13.2 1.4 0.22 12.0 1.4 1.5 1 0 0 1 1 1 0 GINS complex protein DUF4351 PF14261.6 CBZ24538.1 - 0.13 12.3 0.4 19 5.4 0.1 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4351) ERM PF00769.19 CBZ24538.1 - 0.33 10.7 18.7 0.62 9.8 18.7 1.5 1 0 0 1 1 1 0 Ezrin/radixin/moesin family AAA_13 PF13166.6 CBZ24538.1 - 0.41 9.2 8.5 0.61 8.7 8.5 1.1 1 0 0 1 1 1 0 AAA domain LCD1 PF09798.9 CBZ24538.1 - 0.54 8.7 6.2 0.72 8.3 6.2 1.1 1 0 0 1 1 1 0 DNA damage checkpoint protein Spc7 PF08317.11 CBZ24538.1 - 0.62 8.9 10.6 1.2 8.0 10.6 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein LUC7 PF03194.15 CBZ24538.1 - 0.97 9.0 10.1 1.6 8.3 10.1 1.2 1 0 0 1 1 1 0 LUC7 N_terminus TMCO5 PF14992.6 CBZ24538.1 - 2.1 7.8 10.2 3.4 7.2 10.2 1.2 1 0 0 1 1 1 0 TMCO5 family FapA PF03961.13 CBZ24538.1 - 3 6.4 6.9 4.6 5.7 6.9 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A TMF_DNA_bd PF12329.8 CBZ24538.1 - 7.2 6.7 22.7 0.22 11.6 13.9 2.4 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding Abhydrolase_1 PF00561.20 CBZ24539.1 - 1.3e-05 25.0 0.0 4.6e-05 23.2 0.0 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 CBZ24539.1 - 0.0007 18.9 0.0 0.023 14.0 0.0 2.6 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Hydrolase_4 PF12146.8 CBZ24540.1 - 2.2e-05 23.8 0.0 3.9e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 CBZ24540.1 - 0.0014 18.4 0.0 0.0028 17.4 0.0 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold HEAT PF02985.22 CBZ24541.1 - 0.46 10.9 18.4 6.2 7.4 0.0 7.1 7 0 0 7 7 7 0 HEAT repeat ImpA_N PF06812.12 CBZ24541.1 - 8.2 6.6 6.6 1.4 9.0 0.1 3.2 4 0 0 4 4 4 0 ImpA, N-terminal, type VI secretion system Kinesin PF00225.23 CBZ24542.1 - 1e-86 290.9 0.3 1.1e-85 287.5 0.3 2.4 1 1 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 CBZ24542.1 - 1.9e-20 73.3 0.1 5e-20 72.0 0.0 1.8 2 0 0 2 2 2 1 Microtubule binding Exonuc_VII_L PF02601.15 CBZ24542.1 - 0.88 9.1 9.0 3.4 7.2 3.4 2.8 2 1 0 2 2 2 0 Exonuclease VII, large subunit UPF0242 PF06785.11 CBZ24542.1 - 5.8 7.0 7.0 6.5 6.8 2.2 2.5 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus START PF01852.19 CBZ24543.1 - 6.1e-22 78.1 0.0 1.2e-21 77.1 0.0 1.5 1 0 0 1 1 1 1 START domain LRR_6 PF13516.6 CBZ24544.1 - 1.3e-20 71.6 26.7 0.0086 16.1 0.1 11.9 13 0 0 13 13 13 8 Leucine Rich repeat LRR_4 PF12799.7 CBZ24544.1 - 8.6e-13 48.3 12.6 0.0032 17.8 0.3 8.6 9 1 1 10 10 10 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CBZ24544.1 - 6.9e-08 32.1 25.0 0.0051 16.6 3.1 8.1 8 2 1 9 9 9 4 Leucine rich repeat LRR_1 PF00560.33 CBZ24544.1 - 8.2e-08 31.8 9.6 9.3 7.2 0.1 10.1 10 1 0 10 10 10 2 Leucine Rich Repeat Ribosomal_L24e PF01246.20 CBZ24545.1 - 1.9e-32 111.3 3.6 1.9e-32 111.3 3.6 2.5 2 0 0 2 2 2 1 Ribosomal protein L24e zf-FCS PF06467.14 CBZ24545.1 - 0.004 17.1 6.5 0.0069 16.3 6.5 1.3 1 0 0 1 1 1 1 MYM-type Zinc finger with FCS sequence motif zf-FLZ PF04570.14 CBZ24545.1 - 0.37 10.3 4.6 0.91 9.0 4.6 1.6 1 1 0 1 1 1 0 zinc-finger of the FCS-type, C2-C2 AAA PF00004.29 CBZ24546.1 - 1.1e-39 135.9 0.0 3.4e-39 134.3 0.0 1.9 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 CBZ24546.1 - 3.7e-11 42.6 0.4 1.5e-10 40.7 0.0 2.3 2 0 0 2 2 2 1 AAA+ lid domain AAA_2 PF07724.14 CBZ24546.1 - 1.4e-05 25.3 0.0 2.9e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 CBZ24546.1 - 0.00024 21.6 5.0 0.0003 21.2 1.3 3.1 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 CBZ24546.1 - 0.00042 20.6 0.0 0.0018 18.5 0.0 2.1 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.14 CBZ24546.1 - 0.003 17.5 0.1 0.02 14.9 0.1 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_33 PF13671.6 CBZ24546.1 - 0.014 15.5 1.2 0.052 13.7 0.0 2.8 2 0 0 2 2 1 0 AAA domain AAA_18 PF13238.6 CBZ24546.1 - 0.029 14.9 0.0 0.09 13.3 0.0 1.9 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 CBZ24546.1 - 0.037 13.7 0.0 0.081 12.7 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_28 PF13521.6 CBZ24546.1 - 0.049 13.9 0.0 0.2 11.9 0.0 2.2 1 0 0 1 1 1 0 AAA domain RuvB_N PF05496.12 CBZ24546.1 - 0.058 13.1 0.0 0.19 11.5 0.0 1.8 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain Mg_chelatase PF01078.21 CBZ24546.1 - 0.061 12.7 0.1 0.12 11.8 0.1 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_7 PF12775.7 CBZ24546.1 - 0.078 12.5 0.0 0.14 11.7 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region GT-D PF08759.11 CBZ24546.1 - 0.094 12.4 0.1 0.16 11.6 0.1 1.2 1 0 0 1 1 1 0 Glycosyltransferase GT-D fold Bromodomain PF00439.25 CBZ24546.1 - 0.11 12.5 0.0 0.24 11.5 0.0 1.4 1 0 0 1 1 1 0 Bromodomain PUB PF09409.10 CBZ24547.1 - 4.9e-10 39.2 0.0 9.3e-10 38.3 0.0 1.4 1 0 0 1 1 1 1 PUB domain SHOCT PF09851.9 CBZ24547.1 - 0.00058 19.5 0.7 0.00058 19.5 0.7 2.1 2 0 0 2 2 2 1 Short C-terminal domain DUF1682 PF07946.14 CBZ24547.1 - 4.5 6.4 11.4 7.1 5.7 11.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) Ndc1_Nup PF09531.10 CBZ24547.1 - 5.3 5.6 15.3 0.29 9.8 5.4 2.2 2 0 0 2 2 2 0 Nucleoporin protein Ndc1-Nup Surp PF01805.20 CBZ24548.1 - 0.012 15.6 2.4 0.034 14.1 0.3 2.8 3 0 0 3 3 3 0 Surp module FUSC PF04632.12 CBZ24548.1 - 9.6 4.6 6.8 16 3.8 6.8 1.4 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF4311 PF14188.6 CBZ24549.1 - 0.36 10.6 0.6 0.62 9.8 0.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4311) SPT6_acidic PF14632.6 CBZ24550.1 - 0.18 12.4 0.1 0.18 12.4 0.1 2.5 2 0 0 2 2 2 0 Acidic N-terminal SPT6 Ribosomal_S7 PF00177.21 CBZ24551.1 - 4.3e-34 117.3 1.1 5.4e-34 117.0 1.1 1.1 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e Ribosomal_S7 PF00177.21 CBZ24552.1 - 4.3e-34 117.3 1.1 5.4e-34 117.0 1.1 1.1 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e zf-HIT PF04438.16 CBZ24553.1 - 1e-07 31.7 6.5 1.9e-07 30.8 6.5 1.4 1 0 0 1 1 1 1 HIT zinc finger zf-MYND PF01753.18 CBZ24553.1 - 0.018 15.2 3.9 0.034 14.2 3.9 1.4 1 0 0 1 1 1 0 MYND finger zf-FPG_IleRS PF06827.14 CBZ24553.1 - 1 9.3 4.7 2.2 8.2 0.2 2.6 2 0 0 2 2 2 0 Zinc finger found in FPG and IleRS Adaptin_N PF01602.20 CBZ24554.1 - 1.5e-78 264.7 0.0 2.1e-78 264.2 0.0 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 CBZ24554.1 - 2.7e-16 60.0 0.6 1.7e-15 57.4 0.0 2.7 4 0 0 4 4 4 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 CBZ24554.1 - 2.8e-07 30.8 2.6 0.0036 17.7 0.1 4.9 3 1 1 5 5 5 1 HEAT repeats HEAT_EZ PF13513.6 CBZ24554.1 - 0.0021 18.6 10.5 0.16 12.5 0.0 6.1 5 1 1 6 6 6 1 HEAT-like repeat TetR_C_15 PF17918.1 CBZ24554.1 - 0.019 15.7 1.2 0.4 11.5 0.2 3.6 4 0 0 4 4 4 0 Tetracyclin repressor-like, C-terminal domain DUF3137 PF11335.8 CBZ24554.1 - 0.12 12.3 0.1 0.25 11.3 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3137) HEAT PF02985.22 CBZ24554.1 - 0.18 12.2 2.4 31 5.2 0.0 4.8 6 0 0 6 6 6 0 HEAT repeat PEP-utilizers_C PF02896.18 CBZ24555.1 - 7.9e-92 307.5 0.0 1.2e-91 306.9 0.0 1.3 1 0 0 1 1 1 1 PEP-utilising enzyme, TIM barrel domain PPDK_N PF01326.19 CBZ24555.1 - 2e-74 250.8 0.0 4e-72 243.3 0.0 2.1 1 1 0 1 1 1 1 Pyruvate phosphate dikinase, PEP/pyruvate binding domain PEP-utilizers PF00391.23 CBZ24555.1 - 7.1e-28 96.1 0.9 1.6e-27 95.0 0.9 1.6 1 0 0 1 1 1 1 PEP-utilising enzyme, mobile domain HTH_AsnC-type PF13404.6 CBZ24555.1 - 0.0035 17.1 0.2 0.0098 15.7 0.2 1.8 1 0 0 1 1 1 1 AsnC-type helix-turn-helix domain HTH_24 PF13412.6 CBZ24555.1 - 0.0072 15.9 0.0 0.016 14.8 0.0 1.6 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding DUF3788 PF12663.7 CBZ24555.1 - 0.017 15.1 0.0 0.038 13.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3788) Sigma70_r4 PF04545.16 CBZ24555.1 - 0.017 14.6 0.3 0.06 12.9 0.0 2.0 2 0 0 2 2 2 0 Sigma-70, region 4 HTH_11 PF08279.12 CBZ24555.1 - 0.055 13.4 0.0 0.2 11.6 0.0 1.9 1 0 0 1 1 1 0 HTH domain Ovate PF04844.13 CBZ24555.1 - 0.084 12.9 0.0 15 5.7 0.0 2.6 2 0 0 2 2 2 0 Transcriptional repressor, ovate HTH_28 PF13518.6 CBZ24555.1 - 0.13 12.5 0.0 23 5.2 0.0 2.8 2 0 0 2 2 2 0 Helix-turn-helix domain DUF968 PF06147.11 CBZ24555.1 - 0.13 12.5 0.0 0.22 11.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF968) YdaS_antitoxin PF15943.5 CBZ24555.1 - 0.13 12.1 0.6 12 5.8 0.0 3.2 3 0 0 3 3 3 0 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT CAP_N PF01213.19 CBZ24556.1 - 0.26 10.8 1.9 0.45 9.9 1.9 1.3 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal SAT PF16073.5 CBZ24557.1 - 1.4e-10 41.3 0.3 1.4e-10 41.3 0.3 1.8 2 0 0 2 2 2 1 Starter unit:ACP transacylase in aflatoxin biosynthesis Acetone_carb_G PF08882.11 CBZ24558.1 - 0.014 15.5 0.0 0.024 14.8 0.0 1.3 1 0 0 1 1 1 0 Acetone carboxylase gamma subunit HydF_dimer PF18128.1 CBZ24558.1 - 0.02 14.9 0.4 0.048 13.7 0.1 1.8 2 0 0 2 2 2 0 Hydrogen maturase F dimerization domain Phi-29_GP3 PF05435.11 CBZ24558.1 - 0.075 12.5 0.2 0.1 12.0 0.2 1.2 1 0 0 1 1 1 0 Phi-29 DNA terminal protein GP3 SecY PF00344.20 CBZ24560.1 - 4.3e-63 213.4 7.6 5.4e-63 213.1 7.6 1.1 1 0 0 1 1 1 1 SecY translocase Plug_translocon PF10559.9 CBZ24560.1 - 1e-14 54.1 0.0 2.4e-14 52.9 0.0 1.7 1 0 0 1 1 1 1 Plug domain of Sec61p TMEM237 PF15383.6 CBZ24560.1 - 0.0072 15.5 0.2 0.013 14.6 0.2 1.3 1 0 0 1 1 1 1 Transmembrane protein 237 DHHC PF01529.20 CBZ24563.1 - 2.7e-27 95.5 13.2 2.7e-27 95.5 13.2 2.2 1 1 1 2 2 2 1 DHHC palmitoyltransferase MASE5 PF17178.4 CBZ24563.1 - 0.013 15.3 1.6 0.013 15.3 1.6 1.9 2 0 0 2 2 2 0 Membrane-associated sensor DUF373 PF04123.13 CBZ24563.1 - 0.033 13.6 1.6 0.35 10.3 0.2 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF373) XRCC4 PF06632.12 CBZ24563.1 - 1.9 7.3 3.5 3.1 6.6 3.5 1.3 1 0 0 1 1 1 0 DNA double-strand break repair and V(D)J recombination protein XRCC4 DHHC PF01529.20 CBZ24564.1 - 8.7e-23 80.9 15.1 8.7e-23 80.9 15.1 2.2 2 0 0 2 2 2 1 DHHC palmitoyltransferase p450 PF00067.22 CBZ24565.1 - 3.6e-65 220.5 0.0 4.3e-65 220.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Ribosomal_L28e PF01778.17 CBZ24566.1 - 1.1e-18 68.1 0.6 2.2e-18 67.1 0.1 1.6 1 1 0 1 1 1 1 Ribosomal L28e protein family bPH_6 PF10756.9 CBZ24566.1 - 0.0076 16.3 0.7 0.012 15.7 0.7 1.3 1 0 0 1 1 1 1 Bacterial PH domain WD40 PF00400.32 CBZ24567.1 - 7e-08 33.0 11.1 0.015 16.2 0.1 5.6 6 0 0 6 6 6 2 WD domain, G-beta repeat Sec16_C PF12931.7 CBZ24567.1 - 1.2e-05 25.1 0.0 0.0001 22.1 0.0 2.2 1 1 0 1 1 1 1 Sec23-binding domain of Sec16 DUF1170 PF06663.13 CBZ24567.1 - 0.005 16.6 0.3 0.01 15.6 0.3 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1170) TPR_12 PF13424.6 CBZ24567.1 - 0.0094 16.2 1.3 0.26 11.6 0.2 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.28 CBZ24567.1 - 0.049 13.5 0.5 1.2 9.1 0.4 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.17 CBZ24567.1 - 0.72 10.1 7.8 1.6 9.1 0.3 3.4 4 0 0 4 4 4 0 Tetratricopeptide repeat GTP_EFTU PF00009.27 CBZ24568.1 - 2e-41 141.7 0.0 5.1e-41 140.4 0.0 1.8 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 CBZ24568.1 - 1e-28 99.9 0.0 1e-28 99.9 0.0 2.7 3 0 0 3 3 3 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 CBZ24568.1 - 0.00053 20.3 0.5 0.0033 17.8 0.2 2.4 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 CBZ24568.1 - 0.002 18.2 0.0 0.013 15.6 0.0 2.2 1 1 0 1 1 1 1 50S ribosome-binding GTPase G-alpha PF00503.20 CBZ24568.1 - 0.08 12.1 0.0 0.08 12.1 0.0 1.6 2 0 0 2 2 2 0 G-protein alpha subunit GNAT_acetyltr_2 PF13718.6 CBZ24568.1 - 0.37 10.2 6.7 1.7 8.0 6.9 2.0 2 0 0 2 2 2 0 GNAT acetyltransferase 2 60KD_IMP PF02096.20 CBZ24569.1 - 9.8e-11 41.8 0.3 1.8e-10 41.0 0.3 1.4 1 0 0 1 1 1 1 60Kd inner membrane protein Ribosomal_S8 PF00410.19 CBZ24570.1 - 5.4e-21 74.9 0.0 6.8e-21 74.5 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S8 Solute_trans_a PF03619.16 CBZ24571.1 - 5.6e-71 239.2 20.4 7.2e-71 238.8 20.4 1.1 1 0 0 1 1 1 1 Organic solute transporter Ostalpha Prok-RING_2 PF14445.6 CBZ24571.1 - 0.024 14.8 0.5 0.067 13.4 0.5 1.7 1 0 0 1 1 1 0 Prokaryotic RING finger family 2 Skp1 PF01466.19 CBZ24572.1 - 1.3e-26 92.4 2.2 2.1e-26 91.7 2.2 1.4 1 0 0 1 1 1 1 Skp1 family, dimerisation domain Skp1_POZ PF03931.15 CBZ24572.1 - 7.6e-12 45.2 0.0 7.8e-11 42.0 0.0 2.3 2 0 0 2 2 2 1 Skp1 family, tetramerisation domain ABC2_membrane_3 PF12698.7 CBZ24573.1 - 1.1e-53 182.6 68.4 2.4e-38 132.1 26.7 3.1 3 1 0 3 3 3 2 ABC-2 family transporter protein ABC_tran PF00005.27 CBZ24573.1 - 1.4e-44 151.9 0.0 1.6e-28 99.9 0.0 2.5 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 CBZ24573.1 - 5.8e-09 36.2 0.0 0.0011 18.9 0.0 3.3 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 CBZ24573.1 - 3.1e-05 23.9 0.0 0.012 15.5 0.0 2.4 2 0 0 2 2 2 1 RsgA GTPase AAA_23 PF13476.6 CBZ24573.1 - 0.00011 22.8 4.6 0.052 14.0 0.1 2.7 3 0 0 3 3 3 2 AAA domain AAA_29 PF13555.6 CBZ24573.1 - 0.00057 19.6 0.4 0.12 12.1 0.0 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain SRP54 PF00448.22 CBZ24573.1 - 0.0022 17.6 0.3 0.63 9.6 0.0 2.4 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain AAA_30 PF13604.6 CBZ24573.1 - 0.0057 16.4 0.0 1.1 8.9 0.0 2.3 2 0 0 2 2 2 1 AAA domain cobW PF02492.19 CBZ24573.1 - 0.032 13.8 0.2 1.6 8.3 0.0 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_16 PF13191.6 CBZ24573.1 - 0.037 14.4 0.0 1.1 9.6 0.0 2.7 3 0 0 3 3 3 0 AAA ATPase domain MMR_HSR1 PF01926.23 CBZ24573.1 - 0.044 13.9 0.1 3.2 7.9 0.0 2.5 2 0 0 2 2 2 0 50S ribosome-binding GTPase SMC_N PF02463.19 CBZ24573.1 - 0.053 13.0 1.0 9.5 5.6 0.0 2.8 3 0 0 3 3 3 0 RecF/RecN/SMC N terminal domain AAA_15 PF13175.6 CBZ24573.1 - 0.079 12.7 0.1 2.1 8.0 0.0 2.3 2 0 0 2 2 2 0 AAA ATPase domain AAA_28 PF13521.6 CBZ24573.1 - 0.084 13.1 0.1 15 5.8 0.2 2.7 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 CBZ24573.1 - 0.17 12.3 0.1 3.7 8.0 0.0 2.6 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_13 PF13166.6 CBZ24573.1 - 0.24 10.0 0.1 8.4 4.9 0.0 2.1 2 0 0 2 2 2 0 AAA domain ABC2_membrane_3 PF12698.7 CBZ24575.1 - 2e-54 185.0 36.8 4e-35 121.5 13.0 3.0 2 1 0 2 2 2 2 ABC-2 family transporter protein ABC_tran PF00005.27 CBZ24575.1 - 4.9e-52 176.1 0.0 1.2e-27 97.1 0.0 2.4 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 CBZ24575.1 - 7.9e-16 58.7 0.5 1.5e-05 25.0 0.0 4.1 4 0 0 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 CBZ24575.1 - 1.9e-05 24.2 0.0 0.44 9.9 0.0 3.6 3 1 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 CBZ24575.1 - 0.00053 20.6 1.9 0.16 12.5 0.0 2.3 2 0 0 2 2 2 2 AAA domain SRP54 PF00448.22 CBZ24575.1 - 0.0011 18.7 0.3 0.34 10.5 0.0 2.4 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain AAA_29 PF13555.6 CBZ24575.1 - 0.0027 17.4 0.6 0.5 10.1 0.0 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain SbcCD_C PF13558.6 CBZ24575.1 - 0.0032 17.7 0.1 2.4 8.4 0.0 3.9 3 1 0 3 3 2 1 Putative exonuclease SbcCD, C subunit RsgA_GTPase PF03193.16 CBZ24575.1 - 0.0037 17.2 0.2 0.078 12.9 0.0 2.3 2 0 0 2 2 2 1 RsgA GTPase DUF4162 PF13732.6 CBZ24575.1 - 0.0054 17.4 0.0 7.4 7.4 0.0 2.6 2 0 0 2 2 2 2 Domain of unknown function (DUF4162) AAA_16 PF13191.6 CBZ24575.1 - 0.0076 16.6 0.0 2.3 8.6 0.0 2.9 3 0 0 3 3 3 1 AAA ATPase domain AAA_30 PF13604.6 CBZ24575.1 - 0.011 15.5 0.2 1.1 9.0 0.0 2.8 3 0 0 3 3 3 0 AAA domain AAA_15 PF13175.6 CBZ24575.1 - 0.024 14.4 0.0 1.7 8.2 0.0 3.3 4 0 0 4 4 4 0 AAA ATPase domain AAA_22 PF13401.6 CBZ24575.1 - 0.026 14.8 0.1 2.6 8.3 0.0 2.6 2 0 0 2 2 2 0 AAA domain ABC2_membrane_2 PF12679.7 CBZ24575.1 - 0.097 11.9 22.7 1 8.6 12.5 2.5 2 0 0 2 2 2 0 ABC-2 family transporter protein AAA_25 PF13481.6 CBZ24575.1 - 0.28 10.7 0.7 3.5 7.2 0.1 2.5 2 0 0 2 2 2 0 AAA domain cobW PF02492.19 CBZ24575.1 - 0.33 10.5 1.0 6.5 6.3 0.0 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain MukB PF04310.12 CBZ24575.1 - 0.38 10.5 2.0 27 4.5 0.1 2.9 3 0 0 3 3 3 0 MukB N-terminal ABC2_membrane_3 PF12698.7 CBZ24576.1 - 4.7e-54 183.8 66.2 2.4e-38 132.1 26.2 2.9 3 1 0 3 3 3 2 ABC-2 family transporter protein ABC_tran PF00005.27 CBZ24576.1 - 1.4e-52 177.8 0.0 2.1e-28 99.5 0.0 2.6 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 CBZ24576.1 - 3e-13 50.2 0.0 0.0014 18.5 0.0 4.1 4 0 0 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system DUF4162 PF13732.6 CBZ24576.1 - 2e-06 28.4 0.0 0.69 10.7 0.0 3.5 3 0 0 3 3 3 2 Domain of unknown function (DUF4162) RsgA_GTPase PF03193.16 CBZ24576.1 - 1.1e-05 25.4 0.0 0.015 15.2 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA_29 PF13555.6 CBZ24576.1 - 0.00033 20.3 0.7 0.15 11.8 0.0 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain Zeta_toxin PF06414.12 CBZ24576.1 - 0.0017 17.7 0.4 3.9 6.7 0.1 3.3 3 0 0 3 3 3 1 Zeta toxin AAA_16 PF13191.6 CBZ24576.1 - 0.0024 18.2 0.1 1.4 9.3 0.0 3.1 4 0 0 4 4 2 1 AAA ATPase domain AAA_30 PF13604.6 CBZ24576.1 - 0.005 16.6 0.0 1.4 8.6 0.0 2.5 2 0 0 2 2 2 1 AAA domain RCC1_2 PF13540.6 CBZ24576.1 - 0.0057 16.4 0.2 17 5.4 0.0 3.8 3 0 0 3 3 3 0 Regulator of chromosome condensation (RCC1) repeat SbcCD_C PF13558.6 CBZ24576.1 - 0.0095 16.2 0.0 7.9 6.8 0.0 3.3 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit SRP54 PF00448.22 CBZ24576.1 - 0.013 15.1 0.2 3.1 7.4 0.0 2.4 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain MMR_HSR1 PF01926.23 CBZ24576.1 - 0.045 13.8 0.1 4 7.6 0.0 2.7 2 0 0 2 2 2 0 50S ribosome-binding GTPase SMC_N PF02463.19 CBZ24576.1 - 0.049 13.1 0.1 12 5.3 0.0 2.7 3 0 0 3 3 3 0 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 CBZ24576.1 - 0.05 14.1 9.5 0.064 13.7 0.1 3.3 4 0 0 4 4 4 0 AAA domain AAA_28 PF13521.6 CBZ24576.1 - 0.072 13.3 0.2 13 6.0 0.3 2.9 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 CBZ24576.1 - 0.086 13.1 0.0 7.5 6.8 0.0 3.0 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 CBZ24576.1 - 0.1 12.7 0.0 23 5.1 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 CBZ24576.1 - 0.12 12.8 0.1 2.9 8.3 0.0 2.9 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) DUF87 PF01935.17 CBZ24576.1 - 0.19 11.8 0.2 0.48 10.5 0.2 1.7 1 0 0 1 1 1 0 Helicase HerA, central domain MobB PF03205.14 CBZ24576.1 - 0.19 11.6 0.3 8.6 6.3 0.1 2.5 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B cobW PF02492.19 CBZ24576.1 - 1.1 8.9 6.1 1.9 8.0 0.0 2.7 3 0 0 3 3 2 0 CobW/HypB/UreG, nucleotide-binding domain ABC2_membrane_3 PF12698.7 CBZ24578.1 - 2e-68 231.1 64.9 6.6e-49 166.9 19.1 2.9 2 1 0 2 2 2 2 ABC-2 family transporter protein ABC_tran PF00005.27 CBZ24578.1 - 2.6e-51 173.7 0.0 2.5e-25 89.6 0.0 2.5 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 CBZ24578.1 - 3.3e-17 63.3 1.2 1e-06 28.8 0.0 4.2 4 0 0 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 CBZ24578.1 - 1.1e-05 25.3 0.0 1.7 8.3 0.0 4.1 4 0 0 4 4 4 2 AAA ATPase domain SMC_N PF02463.19 CBZ24578.1 - 1.2e-05 24.9 0.0 3 7.2 0.0 3.5 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 CBZ24578.1 - 5.9e-05 23.7 0.9 0.16 12.5 0.0 2.5 2 0 0 2 2 2 2 AAA domain Zeta_toxin PF06414.12 CBZ24578.1 - 0.00043 19.6 0.1 8.3 5.6 0.0 3.3 3 0 0 3 3 3 1 Zeta toxin SbcCD_C PF13558.6 CBZ24578.1 - 0.00048 20.3 0.0 0.75 10.1 0.0 3.5 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit RsgA_GTPase PF03193.16 CBZ24578.1 - 0.00061 19.7 0.0 0.077 12.9 0.0 2.3 2 0 0 2 2 2 1 RsgA GTPase SRP54 PF00448.22 CBZ24578.1 - 0.00063 19.4 0.2 0.19 11.3 0.0 2.3 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain AAA_29 PF13555.6 CBZ24578.1 - 0.0016 18.2 0.1 0.5 10.2 0.0 2.8 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_30 PF13604.6 CBZ24578.1 - 0.007 16.1 0.0 1.1 9.0 0.0 2.3 2 0 0 2 2 2 1 AAA domain DUF4162 PF13732.6 CBZ24578.1 - 0.0075 17.0 0.0 3.3 8.5 0.0 2.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4162) AAA_16 PF13191.6 CBZ24578.1 - 0.026 14.9 0.0 2.4 8.5 0.0 2.9 3 0 0 3 3 2 0 AAA ATPase domain Arf PF00025.21 CBZ24578.1 - 0.1 12.0 0.1 5.1 6.5 0.0 2.5 2 0 0 2 2 2 0 ADP-ribosylation factor family MukB PF04310.12 CBZ24578.1 - 0.14 11.9 0.4 20 4.9 0.0 2.4 2 0 0 2 2 2 0 MukB N-terminal MMR_HSR1 PF01926.23 CBZ24578.1 - 0.16 12.0 0.0 18 5.4 0.0 2.7 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_28 PF13521.6 CBZ24578.1 - 0.18 12.0 0.1 7.7 6.7 0.1 2.5 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 CBZ24578.1 - 0.18 12.1 0.1 4.4 7.6 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.6 CBZ24578.1 - 0.18 12.1 0.2 17 5.7 0.0 2.4 2 0 0 2 2 2 0 AAA domain cobW PF02492.19 CBZ24578.1 - 0.24 11.0 0.6 6.6 6.3 0.0 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain TatD_DNase PF01026.21 CBZ24579.1 - 1.3e-45 155.8 0.0 1.8e-45 155.3 0.0 1.2 1 0 0 1 1 1 1 TatD related DNase Amidohydro_2 PF04909.14 CBZ24579.1 - 0.0025 17.6 0.0 0.21 11.3 0.0 2.3 2 0 0 2 2 2 2 Amidohydrolase ABC2_membrane_3 PF12698.7 CBZ24580.1 - 2.6e-64 217.5 45.4 5.4e-43 147.4 17.0 2.6 2 1 0 2 2 2 2 ABC-2 family transporter protein ABC_tran PF00005.27 CBZ24580.1 - 1.9e-50 170.9 0.0 2.1e-25 89.8 0.0 2.7 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 CBZ24580.1 - 1.5e-19 71.0 0.8 9.1e-08 32.3 0.0 4.3 4 0 0 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 CBZ24580.1 - 7.7e-09 35.3 0.0 0.019 14.4 0.0 3.5 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 CBZ24580.1 - 4.5e-05 24.0 0.4 0.17 12.4 0.0 2.6 2 0 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 CBZ24580.1 - 4.7e-05 23.3 0.0 0.082 12.8 0.0 3.0 3 0 0 3 3 3 2 RsgA GTPase AAA_15 PF13175.6 CBZ24580.1 - 9.6e-05 22.3 0.0 1.8 8.2 0.0 3.5 4 0 0 4 4 3 2 AAA ATPase domain DUF4162 PF13732.6 CBZ24580.1 - 0.00055 20.6 0.3 1.8 9.3 0.1 2.6 2 0 0 2 2 2 2 Domain of unknown function (DUF4162) AAA_29 PF13555.6 CBZ24580.1 - 0.0023 17.6 0.1 0.53 10.1 0.0 2.8 2 0 0 2 2 2 1 P-loop containing region of AAA domain SRP54 PF00448.22 CBZ24580.1 - 0.0025 17.5 1.2 0.44 10.1 0.0 2.6 3 0 0 3 3 2 1 SRP54-type protein, GTPase domain AAA_30 PF13604.6 CBZ24580.1 - 0.0087 15.8 0.0 1.1 8.9 0.0 2.5 2 0 0 2 2 2 1 AAA domain SbcCD_C PF13558.6 CBZ24580.1 - 0.019 15.2 0.0 18 5.7 0.0 3.5 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_16 PF13191.6 CBZ24580.1 - 0.029 14.8 0.0 2.4 8.5 0.0 2.7 2 0 0 2 2 2 0 AAA ATPase domain KdpD PF02702.17 CBZ24580.1 - 0.038 13.4 0.0 0.1 12.0 0.0 1.7 1 0 0 1 1 1 0 Osmosensitive K+ channel His kinase sensor domain Zeta_toxin PF06414.12 CBZ24580.1 - 0.07 12.4 0.1 19 4.5 0.0 2.9 3 0 0 3 3 3 0 Zeta toxin MMR_HSR1 PF01926.23 CBZ24580.1 - 0.092 12.8 0.1 19 5.4 0.0 3.1 3 0 0 3 3 3 0 50S ribosome-binding GTPase AAA_19 PF13245.6 CBZ24580.1 - 0.1 12.9 0.1 11 6.3 0.0 2.6 2 0 0 2 2 2 0 AAA domain MukB PF04310.12 CBZ24580.1 - 0.11 12.3 0.3 18 5.1 0.0 2.6 2 0 0 2 2 2 0 MukB N-terminal AAA_22 PF13401.6 CBZ24580.1 - 0.12 12.6 0.2 7 6.9 0.0 3.2 3 0 0 3 3 3 0 AAA domain Arf PF00025.21 CBZ24580.1 - 0.13 11.7 0.1 5.4 6.4 0.0 2.4 2 0 0 2 2 2 0 ADP-ribosylation factor family AAA_28 PF13521.6 CBZ24580.1 - 0.16 12.2 0.2 7.5 6.8 0.1 2.7 2 0 0 2 2 2 0 AAA domain cobW PF02492.19 CBZ24580.1 - 0.29 10.7 0.8 7 6.2 0.0 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Sigma_reg_N PF13800.6 CBZ24580.1 - 0.35 11.2 1.8 30 5.0 0.0 3.2 2 0 0 2 2 2 0 Sigma factor regulator N-terminal Arm PF00514.23 CBZ24582.1 - 0.0048 16.9 2.1 0.038 14.0 0.1 3.4 4 0 0 4 4 4 1 Armadillo/beta-catenin-like repeat HEAT PF02985.22 CBZ24582.1 - 0.016 15.4 6.0 6.3 7.3 0.1 4.9 5 0 0 5 5 5 0 HEAT repeat Adaptin_N PF01602.20 CBZ24582.1 - 0.017 13.7 3.4 0.62 8.6 0.0 2.4 2 1 0 2 2 2 0 Adaptin N terminal region Rcd1 PF04078.13 CBZ24582.1 - 0.053 12.8 0.1 5.2 6.3 0.0 2.4 2 0 0 2 2 2 0 Cell differentiation family, Rcd1-like HEAT_2 PF13646.6 CBZ24582.1 - 0.13 12.6 0.4 0.13 12.6 0.4 4.1 3 2 1 4 4 4 0 HEAT repeats Frigida PF07899.11 CBZ24583.1 - 0.12 11.6 0.0 0.2 10.9 0.0 1.2 1 0 0 1 1 1 0 Frigida-like protein PapD-like PF14874.6 CBZ24584.1 - 1.1e-45 153.9 0.3 2.6e-45 152.8 0.3 1.6 1 0 0 1 1 1 1 Flagellar-associated PapD-like Nodulin-like PF06813.13 CBZ24585.1 - 8.5e-16 58.2 8.1 8.5e-16 58.2 8.1 2.8 2 1 0 3 3 3 2 Nodulin-like MFS_1 PF07690.16 CBZ24585.1 - 2.5e-10 39.9 46.8 7.6e-09 34.9 10.6 3.5 1 1 1 3 3 3 3 Major Facilitator Superfamily Wzz PF02706.15 CBZ24585.1 - 0.19 12.1 1.6 12 6.3 0.0 3.6 3 0 0 3 3 3 0 Chain length determinant protein BLOC1_2 PF10046.9 CBZ24586.1 - 0.012 15.9 4.1 0.094 13.0 4.4 1.9 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF3450 PF11932.8 CBZ24586.1 - 0.014 14.8 2.5 0.019 14.3 2.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) HAUS-augmin3 PF14932.6 CBZ24586.1 - 0.029 14.0 2.4 0.04 13.5 2.4 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 Ino80_Iec3 PF14612.6 CBZ24586.1 - 0.036 14.7 0.8 0.045 14.4 0.8 1.3 1 0 0 1 1 1 0 IEC3 subunit of the Ino80 complex, chromatin re-modelling DivIC PF04977.15 CBZ24586.1 - 0.038 13.8 0.7 0.038 13.8 0.7 2.1 1 1 1 2 2 2 0 Septum formation initiator KxDL PF10241.9 CBZ24586.1 - 0.042 14.1 2.5 0.11 12.7 0.8 2.0 2 0 0 2 2 2 0 Uncharacterized conserved protein KASH_CCD PF14662.6 CBZ24586.1 - 0.047 13.5 5.0 0.065 13.1 5.0 1.1 1 0 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH FPP PF05911.11 CBZ24586.1 - 0.059 11.6 5.8 0.073 11.3 5.8 1.0 1 0 0 1 1 1 0 Filament-like plant protein, long coiled-coil Uso1_p115_C PF04871.13 CBZ24586.1 - 0.065 13.6 7.7 0.089 13.2 7.7 1.1 1 0 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region DUF4175 PF13779.6 CBZ24586.1 - 1.2 7.0 5.8 1.4 6.7 5.8 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) FliT PF05400.13 CBZ24586.1 - 2.4 9.0 9.3 21 6.0 10.0 1.9 1 1 1 2 2 2 0 Flagellar protein FliT Ribosomal_L4 PF00573.22 CBZ24587.1 - 2.3e-10 40.5 0.0 5.3e-10 39.3 0.0 1.6 1 1 0 1 1 1 1 Ribosomal protein L4/L1 family SH3_9 PF14604.6 CBZ24589.1 - 1.5e-10 40.7 0.0 2.9e-10 39.8 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 CBZ24589.1 - 6.7e-09 35.2 0.0 1.2e-08 34.4 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 CBZ24589.1 - 2.7e-08 33.4 0.0 5.2e-08 32.5 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain Fzo_mitofusin PF04799.13 CBZ24589.1 - 0.71 9.4 4.4 0.24 10.9 0.2 2.2 2 1 0 2 2 2 0 fzo-like conserved region IF-2B PF01008.17 CBZ24590.1 - 4.1e-23 82.0 0.7 3.1e-21 75.8 0.7 2.9 1 1 0 1 1 1 1 Initiation factor 2 subunit family RMMBL PF07521.12 CBZ24590.1 - 0.057 13.4 0.0 0.11 12.4 0.0 1.5 1 0 0 1 1 1 0 Zn-dependent metallo-hydrolase RNA specificity domain PITH PF06201.13 CBZ24591.1 - 2e-25 89.8 0.0 2.4e-25 89.5 0.0 1.1 1 0 0 1 1 1 1 PITH domain Proteasome PF00227.26 CBZ24592.1 - 2.1e-41 141.5 0.8 2.5e-41 141.3 0.8 1.1 1 0 0 1 1 1 1 Proteasome subunit DAP3 PF10236.9 CBZ24593.1 - 2.3e-22 79.6 0.0 2.8e-19 69.5 0.0 2.1 2 0 0 2 2 2 2 Mitochondrial ribosomal death-associated protein 3 T2SSE PF00437.20 CBZ24593.1 - 0.016 14.3 0.0 0.024 13.7 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein ATPase_2 PF01637.18 CBZ24593.1 - 0.046 13.6 0.0 0.22 11.4 0.0 1.9 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea AAA_16 PF13191.6 CBZ24593.1 - 0.086 13.2 0.0 0.16 12.3 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain AAA_29 PF13555.6 CBZ24593.1 - 0.14 11.9 0.0 0.3 10.9 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Isochorismatase PF00857.20 CBZ24596.1 - 1.3e-16 61.3 0.2 2.1e-16 60.6 0.2 1.4 1 1 0 1 1 1 1 Isochorismatase family Cupin_8 PF13621.6 CBZ24597.1 - 8.5 6.0 8.4 30 4.2 6.1 2.6 2 2 1 3 3 3 0 Cupin-like domain Apyrase PF06079.11 CBZ24599.1 - 0.043 13.0 0.0 0.12 11.5 0.0 1.6 2 0 0 2 2 2 0 Apyrase TPR_7 PF13176.6 CBZ24600.1 - 0.093 12.8 0.0 4.1 7.7 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat Plus-3 PF03126.18 CBZ24601.1 - 3.4e-20 72.6 0.0 7e-20 71.6 0.0 1.5 1 0 0 1 1 1 1 Plus-3 domain zf-C3HC4_3 PF13920.6 CBZ24601.1 - 4.7e-08 32.8 17.4 7.3e-08 32.2 17.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Vps39_2 PF10367.9 CBZ24601.1 - 0.1 13.1 4.3 0.2 12.1 4.3 1.6 1 0 0 1 1 1 0 Vacuolar sorting protein 39 domain 2 SelB-wing_1 PF09105.10 CBZ24601.1 - 0.12 12.4 0.6 0.2 11.6 0.6 1.4 1 0 0 1 1 1 0 Elongation factor SelB, winged helix Tropomyosin_1 PF12718.7 CBZ24603.1 - 2.2e-06 27.9 5.6 2.2e-06 27.9 5.6 6.2 2 1 5 7 7 7 1 Tropomyosin like RPW8 PF05659.11 CBZ24603.1 - 0.0026 17.4 2.9 0.15 11.7 0.0 3.6 3 1 0 3 3 3 1 Arabidopsis broad-spectrum mildew resistance protein RPW8 TolA_bind_tri PF16331.5 CBZ24603.1 - 0.0054 16.8 5.7 0.0054 16.8 5.7 8.0 4 3 3 8 8 8 2 TolA binding protein trimerisation Sec8_exocyst PF04048.14 CBZ24603.1 - 0.26 11.2 13.1 0.094 12.6 1.0 4.5 3 1 0 3 3 3 0 Sec8 exocyst complex component specific domain XhlA PF10779.9 CBZ24603.1 - 0.7 10.1 9.7 17 5.7 0.0 6.2 6 0 0 6 6 6 0 Haemolysin XhlA DUF1664 PF07889.12 CBZ24603.1 - 1.7 8.7 49.6 0.054 13.5 1.0 8.8 1 1 6 9 9 9 0 Protein of unknown function (DUF1664) Utp12 PF04003.12 CBZ24603.1 - 4.9 7.5 6.4 1.2 9.4 0.1 3.4 3 0 0 3 3 3 0 Dip2/Utp12 Family Pkinase PF00069.25 CBZ24604.1 - 1.5e-38 132.7 0.0 4.4e-18 65.6 0.0 3.5 3 1 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ24604.1 - 6.4e-16 58.4 0.0 2.7e-08 33.4 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.23 CBZ24604.1 - 0.0071 16.3 0.4 3.8 7.3 0.0 2.5 1 1 0 2 2 2 2 Phosphotransferase enzyme family MFS_1_like PF12832.7 CBZ24605.1 - 3.4 6.4 7.6 1.7 7.4 4.5 1.8 2 0 0 2 2 2 0 MFS_1 like family LRR_8 PF13855.6 CBZ24606.1 - 2.5e-12 46.4 0.5 0.00071 19.3 0.0 3.5 2 1 1 3 3 3 3 Leucine rich repeat LRR_4 PF12799.7 CBZ24606.1 - 3.5e-11 43.2 3.0 0.0013 19.1 0.0 4.0 2 2 2 4 4 4 4 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 CBZ24606.1 - 0.024 14.1 0.0 6.2 6.3 0.0 2.2 2 0 0 2 2 2 0 Leucine-rich repeat LRR_6 PF13516.6 CBZ24606.1 - 0.044 13.8 10.8 42 4.6 0.0 5.7 6 0 0 6 6 6 0 Leucine Rich repeat Glyco_transf_22 PF03901.17 CBZ24607.1 - 5.7e-51 174.0 30.4 1.5e-39 136.4 22.0 3.1 3 0 0 3 3 3 3 Alg9-like mannosyltransferase family TetR_C_14 PF17754.1 CBZ24607.1 - 0.02 14.8 0.7 0.065 13.2 0.7 1.8 1 0 0 1 1 1 0 MftR C-terminal domain UCH PF00443.29 CBZ24610.1 - 3e-22 79.4 0.0 2.5e-20 73.1 0.0 2.4 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 CBZ24610.1 - 3.1e-05 23.7 0.0 0.15 11.6 0.0 3.4 3 0 0 3 3 3 3 Ubiquitin carboxyl-terminal hydrolase AAA PF00004.29 CBZ24612.1 - 3.5e-45 153.7 0.1 1.4e-44 151.7 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 CBZ24612.1 - 1.1e-09 38.1 0.8 3.1e-09 36.6 0.0 2.2 3 0 0 3 3 1 1 Proteasomal ATPase OB C-terminal domain AAA_lid_3 PF17862.1 CBZ24612.1 - 2.3e-09 36.9 0.0 5.8e-09 35.6 0.0 1.7 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 CBZ24612.1 - 2e-08 34.4 0.1 7.3e-08 32.5 0.1 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 CBZ24612.1 - 1.4e-07 32.1 0.5 1.9e-05 25.1 0.0 2.7 2 1 1 3 3 2 1 AAA ATPase domain AAA_2 PF07724.14 CBZ24612.1 - 7.1e-07 29.5 0.2 3.4e-06 27.3 0.0 2.1 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 CBZ24612.1 - 2.2e-05 24.7 1.9 0.0081 16.4 0.7 3.2 2 1 0 2 2 2 1 AAA domain DUF815 PF05673.13 CBZ24612.1 - 8.7e-05 21.8 0.0 0.00017 20.9 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF815) RuvB_N PF05496.12 CBZ24612.1 - 0.00044 20.0 0.0 0.0012 18.6 0.0 1.8 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_28 PF13521.6 CBZ24612.1 - 0.00048 20.4 0.0 0.00094 19.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_7 PF12775.7 CBZ24612.1 - 0.00052 19.6 0.1 0.0025 17.4 0.0 2.0 2 1 0 2 2 2 1 P-loop containing dynein motor region AAA_18 PF13238.6 CBZ24612.1 - 0.00074 20.1 0.0 0.0016 19.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain NACHT PF05729.12 CBZ24612.1 - 0.00091 19.2 1.1 0.05 13.5 0.0 3.5 3 1 1 4 4 4 1 NACHT domain AAA_30 PF13604.6 CBZ24612.1 - 0.0019 18.0 0.1 0.0067 16.2 0.1 2.0 1 1 0 1 1 1 1 AAA domain NTPase_1 PF03266.15 CBZ24612.1 - 0.0022 17.9 0.2 0.0089 15.9 0.1 2.1 3 0 0 3 3 2 1 NTPase TniB PF05621.11 CBZ24612.1 - 0.0024 17.3 0.3 0.31 10.4 0.0 3.0 3 1 1 4 4 4 1 Bacterial TniB protein AAA_3 PF07726.11 CBZ24612.1 - 0.0032 17.3 0.0 0.012 15.5 0.0 2.0 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 CBZ24612.1 - 0.0034 17.5 0.0 0.0081 16.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.6 CBZ24612.1 - 0.0037 17.3 0.0 0.011 15.7 0.0 1.8 2 0 0 2 2 2 1 AAA domain Mg_chelatase PF01078.21 CBZ24612.1 - 0.0074 15.7 0.1 0.021 14.2 0.1 1.7 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI TsaE PF02367.17 CBZ24612.1 - 0.01 15.8 0.0 0.02 14.9 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE TIP49 PF06068.13 CBZ24612.1 - 0.014 14.6 0.0 0.038 13.2 0.0 1.6 1 1 0 1 1 1 0 TIP49 P-loop domain AAA_24 PF13479.6 CBZ24612.1 - 0.02 14.6 0.1 0.047 13.4 0.1 1.7 1 1 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 CBZ24612.1 - 0.025 15.0 0.0 0.063 13.7 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA_19 PF13245.6 CBZ24612.1 - 0.027 14.8 0.2 0.088 13.1 0.1 1.8 2 0 0 2 2 1 0 AAA domain IstB_IS21 PF01695.17 CBZ24612.1 - 0.029 14.1 0.0 0.066 12.9 0.0 1.7 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_11 PF13086.6 CBZ24612.1 - 0.03 14.1 0.9 0.15 11.8 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.6 CBZ24612.1 - 0.033 13.8 0.6 0.2 11.2 0.1 2.2 1 1 1 2 2 2 0 AAA domain Sigma54_activat PF00158.26 CBZ24612.1 - 0.034 13.9 0.1 0.9 9.2 0.0 2.4 2 0 0 2 2 2 0 Sigma-54 interaction domain ATPase PF06745.13 CBZ24612.1 - 0.036 13.4 2.7 1 8.7 0.0 2.9 3 0 0 3 3 3 0 KaiC ATPase_2 PF01637.18 CBZ24612.1 - 0.036 14.0 1.0 0.22 11.4 0.1 2.5 2 1 1 3 3 3 0 ATPase domain predominantly from Archaea Bac_DnaA PF00308.18 CBZ24612.1 - 0.043 13.7 0.0 0.085 12.7 0.0 1.5 1 0 0 1 1 1 0 Bacterial dnaA protein ABC_tran PF00005.27 CBZ24612.1 - 0.05 14.1 0.1 0.21 12.1 0.0 2.3 2 2 0 2 2 2 0 ABC transporter cobW PF02492.19 CBZ24612.1 - 0.072 12.7 0.0 0.19 11.3 0.0 1.7 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain Ins_P5_2-kin PF06090.12 CBZ24612.1 - 0.095 12.1 0.0 0.11 12.0 0.0 1.2 1 0 0 1 1 1 0 Inositol-pentakisphosphate 2-kinase EzrA PF06160.12 CBZ24612.1 - 0.12 10.5 2.5 0.17 10.0 2.5 1.1 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA DUF465 PF04325.13 CBZ24612.1 - 0.2 11.7 1.2 0.43 10.7 1.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF465) HAGH_C PF16123.5 CBZ24613.1 - 5.1e-08 33.3 0.0 1.2e-07 32.2 0.0 1.6 1 0 0 1 1 1 1 Hydroxyacylglutathione hydrolase C-terminus Lactamase_B PF00753.27 CBZ24613.1 - 1.8e-05 24.9 3.0 6.8e-05 22.9 3.0 2.0 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 CBZ24613.1 - 0.048 13.2 0.1 0.13 11.7 0.1 1.7 1 1 1 2 2 2 0 Beta-lactamase superfamily domain tRNA-synt_1e PF01406.19 CBZ24616.1 - 3.6e-114 381.2 0.0 5.6e-114 380.6 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1c PF00749.21 CBZ24616.1 - 0.00075 18.5 1.1 0.0065 15.4 0.0 2.5 2 0 0 2 2 2 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1 PF00133.22 CBZ24616.1 - 0.0014 17.0 0.1 0.092 11.0 0.0 2.8 3 0 0 3 3 3 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.11 CBZ24616.1 - 0.0015 17.3 3.5 0.0063 15.3 0.0 3.1 4 0 0 4 4 4 1 tRNA synthetases class I (M) HA2 PF04408.23 CBZ24617.1 - 4e-05 23.9 0.0 9.8e-05 22.6 0.0 1.6 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.31 CBZ24617.1 - 7.2e-05 23.1 0.0 0.00016 22.0 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-C2H2_jaz PF12171.8 CBZ24617.1 - 0.0065 16.7 1.4 0.013 15.8 1.4 1.5 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 CBZ24617.1 - 0.0072 16.7 4.4 0.018 15.4 4.4 1.8 1 0 0 1 1 1 1 Zinc-finger of C2H2 type SET PF00856.28 CBZ24618.1 - 7.9e-06 26.4 1.8 0.08 13.3 0.0 3.0 1 1 1 2 2 2 2 SET domain Orn_Arg_deC_N PF02784.16 CBZ24619.1 - 4.7e-82 275.1 0.0 6.1e-82 274.7 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.22 CBZ24619.1 - 2.9e-12 46.7 0.0 1e-11 44.9 0.0 2.0 1 1 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain AP_endonuc_2 PF01261.24 CBZ24619.1 - 0.073 12.5 0.0 0.21 11.0 0.0 1.7 1 0 0 1 1 1 0 Xylose isomerase-like TIM barrel Glycoprotein_G PF00802.19 CBZ24619.1 - 0.2 11.0 0.1 0.31 10.4 0.1 1.2 1 0 0 1 1 1 0 Pneumovirus attachment glycoprotein G KxDL PF10241.9 CBZ24620.1 - 0.0056 16.9 9.0 0.0056 16.9 9.0 7.1 6 2 2 8 8 8 2 Uncharacterized conserved protein SAC3_GANP PF03399.16 CBZ24621.1 - 7.9e-15 55.0 0.1 4.1e-14 52.6 0.1 2.1 1 1 0 1 1 1 1 SAC3/GANP family LrgB PF04172.16 CBZ24622.1 - 0.023 14.2 1.1 0.041 13.4 0.0 1.9 2 0 0 2 2 2 0 LrgB-like family Myotub-related PF06602.14 CBZ24623.1 - 6.2e-59 199.7 0.0 1.2e-31 109.9 0.0 3.0 3 0 0 3 3 3 2 Myotubularin-like phosphatase domain NOT2_3_5 PF04153.18 CBZ24626.1 - 3.5e-22 78.9 0.2 3.5e-22 78.9 0.2 3.5 3 0 0 3 3 3 1 NOT2 / NOT3 / NOT5 family Sin_N PF04801.13 CBZ24626.1 - 0.74 9.0 29.9 1.3 8.1 29.9 1.3 1 0 0 1 1 1 0 Sin-like protein conserved region KduI PF04962.12 CBZ24626.1 - 1.6 8.0 6.6 13 5.0 0.2 2.6 2 0 0 2 2 2 0 KduI/IolB family DUF572 PF04502.13 CBZ24626.1 - 3.9 7.0 16.7 0.41 10.2 12.0 1.7 2 0 0 2 2 2 0 Family of unknown function (DUF572) GST_N_3 PF13417.6 CBZ24627.1 - 2.6e-10 40.6 0.0 6.5e-10 39.3 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 CBZ24627.1 - 2.7e-10 40.4 0.0 5.1e-10 39.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 CBZ24627.1 - 1.2e-07 31.9 0.0 2.3e-07 31.0 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 CBZ24627.1 - 0.0003 20.9 0.1 0.00095 19.3 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 CBZ24627.1 - 0.0089 16.2 0.0 0.018 15.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain FA_synthesis PF02504.15 CBZ24627.1 - 0.18 10.9 0.5 0.39 9.7 0.2 1.6 1 1 1 2 2 2 0 Fatty acid synthesis protein DUF2695 PF10905.8 CBZ24628.1 - 0.082 13.1 0.0 0.21 11.8 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2695) PUF PF00806.19 CBZ24629.1 - 7.7e-35 116.6 7.3 9.2e-06 25.1 0.1 7.6 7 0 0 7 7 7 7 Pumilio-family RNA binding repeat DapB_N PF01113.20 CBZ24630.1 - 0.0018 18.4 0.1 0.0044 17.1 0.1 1.7 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus NAD_binding_10 PF13460.6 CBZ24630.1 - 0.027 14.4 0.3 0.28 11.0 0.1 2.3 2 0 0 2 2 2 0 NAD(P)H-binding Epimerase PF01370.21 CBZ24630.1 - 0.047 13.2 0.1 0.085 12.3 0.1 1.4 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family S1-P1_nuclease PF02265.16 CBZ24631.1 - 3.8e-60 203.8 0.0 4.6e-60 203.6 0.0 1.1 1 0 0 1 1 1 1 S1/P1 Nuclease DUF866 PF05907.13 CBZ24633.1 - 7.8e-34 116.8 0.0 9.2e-34 116.6 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF866) Elf1 PF05129.13 CBZ24633.1 - 0.054 13.5 0.8 0.11 12.5 0.1 1.9 2 0 0 2 2 2 0 Transcription elongation factor Elf1 like TK PF00265.18 CBZ24633.1 - 0.11 12.4 0.4 0.29 11.0 0.2 1.6 2 0 0 2 2 2 0 Thymidine kinase Bromodomain PF00439.25 CBZ24635.1 - 0.062 13.4 0.0 8.6 6.5 0.0 2.3 2 0 0 2 2 2 0 Bromodomain DUF1488 PF07369.11 CBZ24637.1 - 1.1 9.4 3.9 3.9 7.5 0.2 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1488) Cas_APE2256 PF09651.10 CBZ24640.1 - 0.15 12.0 0.0 0.29 11.0 0.0 1.4 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_APE2256) WW PF00397.26 CBZ24643.1 - 4.1e-09 36.4 0.1 7.9e-09 35.4 0.1 1.5 1 0 0 1 1 1 1 WW domain ATP-synt_F PF01990.17 CBZ24644.1 - 2.5e-33 114.3 0.0 3.1e-33 114.0 0.0 1.1 1 0 0 1 1 1 1 ATP synthase (F/14-kDa) subunit SSXT PF05030.12 CBZ24644.1 - 0.11 12.1 0.0 0.19 11.4 0.0 1.3 1 0 0 1 1 1 0 SSXT protein (N-terminal region) PGI PF00342.19 CBZ24645.1 - 2.5e-263 874.0 4.2 2.8e-263 873.8 4.2 1.0 1 0 0 1 1 1 1 Phosphoglucose isomerase DUF4473 PF14747.6 CBZ24645.1 - 0.015 15.9 0.1 0.042 14.4 0.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4473) OsmC PF02566.19 CBZ24646.1 - 0.0085 16.6 0.0 0.019 15.5 0.0 1.5 1 1 0 1 1 1 1 OsmC-like protein E3_binding PF02817.17 CBZ24646.1 - 0.083 13.3 0.0 0.2 12.1 0.0 1.7 1 0 0 1 1 1 0 e3 binding domain TPR_19 PF14559.6 CBZ24648.1 - 0.0005 20.5 27.3 0.14 12.7 0.5 7.4 7 1 0 8 8 8 3 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 CBZ24648.1 - 0.0046 17.0 0.1 0.054 13.6 0.3 2.7 3 0 0 3 3 3 1 Fis1 C-terminal tetratricopeptide repeat TPR_2 PF07719.17 CBZ24648.1 - 0.0087 16.1 1.4 0.0087 16.1 1.4 8.0 9 1 1 10 10 10 1 Tetratricopeptide repeat TPR_1 PF00515.28 CBZ24648.1 - 0.022 14.6 9.6 2.6 8.0 0.5 5.8 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_8 PF13181.6 CBZ24648.1 - 0.83 10.0 14.3 29 5.2 0.2 7.2 9 0 0 9 9 9 0 Tetratricopeptide repeat ANAPC3 PF12895.7 CBZ24648.1 - 2.9 8.2 16.3 0.25 11.6 1.7 4.2 3 1 1 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 FUSC_2 PF13515.6 CBZ24649.1 - 7.6e-18 64.9 23.0 6e-16 58.7 10.2 3.3 3 0 0 3 3 3 2 Fusaric acid resistance protein-like FUSC_2 PF13515.6 CBZ24650.1 - 2.6e-11 43.7 4.7 2.6e-11 43.7 4.7 2.6 2 0 0 2 2 2 2 Fusaric acid resistance protein-like ALMT PF11744.8 CBZ24650.1 - 0.064 12.1 3.0 0.049 12.5 0.1 2.0 2 0 0 2 2 2 0 Aluminium activated malate transporter DUF3021 PF11457.8 CBZ24650.1 - 4.1 7.7 9.3 0.42 10.9 1.5 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF3021) Sulfatase PF00884.23 CBZ24651.1 - 3.9e-06 26.5 0.1 2.7e-05 23.7 0.1 2.1 1 1 0 1 1 1 1 Sulfatase Phosphodiest PF01663.22 CBZ24651.1 - 0.00027 20.6 0.0 0.24 11.0 0.0 2.3 2 1 0 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase TPR_8 PF13181.6 CBZ24652.1 - 2.7e-17 61.4 0.2 2.7e-05 24.0 0.0 6.8 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_1 PF00515.28 CBZ24652.1 - 8e-17 60.3 14.2 6.9e-05 22.5 0.0 6.1 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_2 PF07719.17 CBZ24652.1 - 8.5e-16 56.7 25.4 0.0016 18.4 0.0 8.1 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_19 PF14559.6 CBZ24652.1 - 1.4e-11 44.7 10.8 5.2e-05 23.7 0.1 5.1 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_11 PF13414.6 CBZ24652.1 - 4.5e-11 42.3 16.9 1.6e-05 24.5 0.1 4.7 4 1 1 5 5 5 2 TPR repeat TPR_14 PF13428.6 CBZ24652.1 - 1.5e-10 41.0 25.4 0.00011 22.7 0.2 7.2 6 2 2 8 8 6 3 Tetratricopeptide repeat TPR_16 PF13432.6 CBZ24652.1 - 1.3e-09 38.6 30.9 5.5e-05 23.7 0.6 6.3 5 1 1 6 6 5 4 Tetratricopeptide repeat ANAPC8 PF04049.13 CBZ24652.1 - 1.5e-05 25.1 0.0 0.00013 22.0 0.0 2.2 1 1 0 1 1 1 1 Anaphase promoting complex subunit 8 / Cdc23 TPR_12 PF13424.6 CBZ24652.1 - 3.2e-05 24.1 27.1 0.17 12.2 1.7 6.2 4 1 2 6 6 6 5 Tetratricopeptide repeat TPR_15 PF13429.6 CBZ24652.1 - 3.3e-05 23.2 8.0 3.3e-05 23.2 8.0 1.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_17 PF13431.6 CBZ24652.1 - 0.0019 18.5 2.4 1.9 9.1 0.2 4.5 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_9 PF13371.6 CBZ24652.1 - 0.0025 17.9 17.1 0.16 12.1 0.7 5.0 3 1 2 5 5 4 2 Tetratricopeptide repeat FAT PF02259.23 CBZ24652.1 - 0.0054 16.0 0.3 0.27 10.4 0.1 2.6 1 1 2 3 3 3 1 FAT domain ANAPC3 PF12895.7 CBZ24652.1 - 0.0087 16.3 21.4 0.018 15.2 0.8 6.0 5 1 1 6 6 6 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.6 CBZ24652.1 - 0.043 13.9 18.1 2.6 8.3 0.2 6.0 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_10 PF13374.6 CBZ24652.1 - 0.18 11.7 13.6 0.29 11.1 0.5 4.4 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_6 PF13174.6 CBZ24652.1 - 0.29 11.9 9.2 2 9.2 0.0 4.9 6 0 0 6 6 4 0 Tetratricopeptide repeat Aminotran_1_2 PF00155.21 CBZ24654.1 - 4.4e-32 111.7 0.0 5.6e-32 111.3 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Ribonuc_red_lgN PF00317.21 CBZ24654.1 - 0.06 13.4 0.0 0.33 11.0 0.0 2.1 2 0 0 2 2 2 0 Ribonucleotide reductase, all-alpha domain PPL5 PF18168.1 CBZ24655.1 - 2.2e-138 460.9 0.0 2.8e-138 460.6 0.0 1.1 1 0 0 1 1 1 1 Prim-pol family 5 PriCT_2 PF08707.11 CBZ24655.1 - 7.4e-13 48.7 0.1 2.3e-12 47.1 0.1 1.9 1 0 0 1 1 1 1 Primase C terminal 2 (PriCT-2) MCM2_N PF12619.8 CBZ24655.1 - 0.041 14.2 0.4 0.041 14.2 0.4 1.7 2 0 0 2 2 2 0 Mini-chromosome maintenance protein 2 Trp_syntA PF00290.20 CBZ24655.1 - 0.12 11.2 0.0 0.19 10.5 0.0 1.2 1 0 0 1 1 1 0 Tryptophan synthase alpha chain PBP1_TM PF14812.6 CBZ24655.1 - 0.3 11.5 1.5 0.58 10.6 1.5 1.5 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Pns11_12 PF17464.2 CBZ24656.1 - 0.4 10.4 7.2 0.87 9.3 7.2 1.5 1 0 0 1 1 1 0 Non-structural protein 11 and 12 Cwf_Cwc_15 PF04889.12 CBZ24656.1 - 0.52 10.0 16.8 0.94 9.2 16.8 1.4 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein TFIIA PF03153.13 CBZ24656.1 - 0.56 10.2 11.3 1 9.3 11.3 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF1682 PF07946.14 CBZ24656.1 - 0.57 9.3 7.4 0.89 8.7 7.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) Metallophos PF00149.28 CBZ24657.1 - 2.3e-28 100.1 0.0 4.1e-28 99.3 0.0 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase EF-hand_1 PF00036.32 CBZ24657.1 - 0.00036 19.9 0.0 0.056 13.0 0.0 3.1 3 0 0 3 3 3 1 EF hand zf-TRAF PF02176.18 CBZ24657.1 - 0.0017 19.0 3.4 0.0017 19.0 3.4 3.0 1 1 2 3 3 3 1 TRAF-type zinc finger EF-hand_6 PF13405.6 CBZ24657.1 - 0.0057 16.5 0.5 0.45 10.6 0.0 3.8 4 1 1 5 5 5 1 EF-hand domain EF-hand_7 PF13499.6 CBZ24657.1 - 0.0062 17.0 0.5 0.22 12.0 0.0 2.9 3 1 0 4 4 4 1 EF-hand domain pair EF-hand_8 PF13833.6 CBZ24657.1 - 0.026 14.4 0.1 0.79 9.6 0.0 2.8 1 1 1 2 2 2 0 EF-hand domain pair zf_UBZ PF18439.1 CBZ24657.1 - 0.039 13.5 0.0 0.039 13.5 0.0 3.3 3 0 0 3 3 3 0 Ubiquitin-Binding Zinc Finger DUF2267 PF10025.9 CBZ24657.1 - 0.18 12.1 0.0 24 5.2 0.1 2.7 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2267) zinc_ribbon_2 PF13240.6 CBZ24657.1 - 2.6 7.9 12.1 1.9 8.3 0.2 4.0 4 0 0 4 4 4 0 zinc-ribbon domain DZR PF12773.7 CBZ24657.1 - 9.5 6.3 15.2 0.63 10.1 7.5 2.5 2 0 0 2 2 2 0 Double zinc ribbon AAA-ATPase_like PF09820.9 CBZ24658.1 - 0.043 13.2 0.3 1.5 8.2 0.0 2.1 2 0 0 2 2 2 0 Predicted AAA-ATPase BBL5 PF07289.11 CBZ24659.1 - 1.8e-132 441.4 0.0 2.1e-132 441.2 0.0 1.0 1 0 0 1 1 1 1 Bardet-Biedl syndrome 5 protein Vps36_ESCRT-II PF11605.8 CBZ24659.1 - 0.011 15.9 0.0 0.79 9.9 0.0 2.3 2 0 0 2 2 2 0 Vacuolar protein sorting protein 36 Vps36 Voldacs PF03517.13 CBZ24659.1 - 0.011 15.8 0.0 0.6 10.2 0.0 2.4 2 0 0 2 2 2 0 Regulator of volume decrease after cellular swelling LRR_6 PF13516.6 CBZ24661.1 - 7.8e-20 69.2 24.0 0.026 14.6 0.0 11.0 11 0 0 11 11 11 7 Leucine Rich repeat LRR_4 PF12799.7 CBZ24661.1 - 7.6e-07 29.4 10.0 0.31 11.5 0.0 7.1 6 1 2 8 8 8 1 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 CBZ24661.1 - 1.3e-05 25.1 1.6 7.2 7.6 0.0 6.6 6 1 0 6 6 6 1 Leucine Rich Repeat LRR_8 PF13855.6 CBZ24661.1 - 0.00066 19.4 12.1 4.6 7.1 0.1 6.8 6 2 0 6 6 6 2 Leucine rich repeat NCOA_u2 PF16665.5 CBZ24661.1 - 0.24 11.7 2.4 0.69 10.2 2.4 1.7 1 0 0 1 1 1 0 Unstructured region on nuclear receptor coactivator protein Lectin_N PF03954.14 CBZ24661.1 - 0.32 10.8 4.7 0.17 11.6 0.1 2.8 2 1 0 2 2 2 0 Hepatic lectin, N-terminal domain TPR_MLP1_2 PF07926.12 CBZ24661.1 - 5.4 7.1 33.1 0.62 10.1 27.2 2.2 1 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein DUF962 PF06127.11 CBZ24662.1 - 2.7e-24 85.1 0.2 3e-24 84.9 0.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF962) DUF4491 PF14898.6 CBZ24662.1 - 0.064 13.7 0.1 0.095 13.2 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4491) UCR_Fe-S_N PF10399.9 CBZ24662.1 - 0.19 11.1 0.3 0.19 11.1 0.3 2.3 2 0 0 2 2 2 0 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal LRR_4 PF12799.7 CBZ24663.1 - 1.2e-16 60.5 0.1 0.025 15.0 0.0 6.8 5 2 0 5 5 5 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CBZ24663.1 - 3e-12 46.1 3.7 0.0025 17.6 0.1 5.7 5 1 1 6 6 6 3 Leucine rich repeat MOR2-PAG1_C PF14225.6 CBZ24663.1 - 0.00079 19.4 8.7 0.091 12.6 0.0 4.6 2 1 3 5 5 5 2 Cell morphogenesis C-terminal LRRNT_2 PF08263.12 CBZ24663.1 - 0.035 14.4 0.6 0.035 14.4 0.6 2.4 2 0 0 2 2 2 0 Leucine rich repeat N-terminal domain T4SS PF07996.11 CBZ24663.1 - 0.099 13.0 0.1 36 4.7 0.0 3.8 3 2 0 4 4 4 0 Type IV secretion system proteins LRR_1 PF00560.33 CBZ24663.1 - 3.9 8.4 4.6 2e+02 3.2 0.1 4.9 7 0 0 7 7 7 0 Leucine Rich Repeat LRR_4 PF12799.7 CBZ24664.1 - 0.00099 19.5 0.0 0.03 14.7 0.1 2.2 1 1 1 2 2 2 1 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CBZ24664.1 - 0.0068 16.2 0.1 0.014 15.1 0.1 1.5 1 1 0 1 1 1 1 Leucine rich repeat LRR_1 PF00560.33 CBZ24664.1 - 0.14 12.8 0.1 58 4.8 0.1 3.2 3 0 0 3 3 3 0 Leucine Rich Repeat Retinal PF15449.6 CBZ24664.1 - 0.16 9.8 27.5 0.2 9.4 27.5 1.0 1 0 0 1 1 1 0 Retinal protein SOG2 PF10428.9 CBZ24664.1 - 2.2 7.4 23.8 2.5 7.2 23.8 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein LRR_8 PF13855.6 CBZ24665.1 - 2.1e-05 24.2 0.0 0.088 12.6 0.0 2.9 1 1 3 4 4 4 4 Leucine rich repeat LRR_4 PF12799.7 CBZ24665.1 - 3e-05 24.3 0.1 0.54 10.8 0.0 3.0 2 1 1 3 3 3 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CBZ24666.1 - 0.00062 19.5 0.0 0.39 10.5 0.0 2.9 1 1 3 4 4 4 3 Leucine rich repeat LRR_4 PF12799.7 CBZ24666.1 - 0.0011 19.3 0.1 0.96 10.0 0.0 2.9 3 0 0 3 3 3 2 Leucine Rich repeats (2 copies) LRRNT_2 PF08263.12 CBZ24666.1 - 0.0032 17.7 1.4 0.0087 16.3 0.1 2.4 2 0 0 2 2 2 1 Leucine rich repeat N-terminal domain LRR_8 PF13855.6 CBZ24667.1 - 6e-06 25.9 0.1 0.2 11.4 0.0 3.3 1 1 3 4 4 4 4 Leucine rich repeat LRR_4 PF12799.7 CBZ24667.1 - 0.0001 22.6 0.4 1.2 9.7 0.0 3.5 3 1 0 3 3 3 2 Leucine Rich repeats (2 copies) LRRNT_2 PF08263.12 CBZ24667.1 - 0.0041 17.4 1.4 0.01 16.1 0.1 2.4 2 0 0 2 2 2 1 Leucine rich repeat N-terminal domain LRR_4 PF12799.7 CBZ24668.1 - 1.1e-16 60.6 0.1 0.025 15.0 0.0 6.8 5 2 0 5 5 5 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CBZ24668.1 - 2.8e-12 46.2 3.8 0.0024 17.6 0.1 5.7 5 1 1 6 6 6 3 Leucine rich repeat MOR2-PAG1_C PF14225.6 CBZ24668.1 - 0.0008 19.3 8.9 0.094 12.6 0.0 4.6 2 1 3 5 5 5 2 Cell morphogenesis C-terminal LRRNT_2 PF08263.12 CBZ24668.1 - 0.035 14.4 0.6 0.035 14.4 0.6 2.4 2 0 0 2 2 2 0 Leucine rich repeat N-terminal domain T4SS PF07996.11 CBZ24668.1 - 0.096 13.1 0.2 36 4.7 0.0 3.9 3 2 0 4 4 4 0 Type IV secretion system proteins LRR_1 PF00560.33 CBZ24668.1 - 4.1 8.3 4.7 1.9e+02 3.2 0.1 4.9 7 0 0 7 7 7 0 Leucine Rich Repeat LRR_8 PF13855.6 CBZ24669.1 - 1.6e-22 79.1 11.9 1.7e-06 27.7 0.8 7.1 2 2 5 8 8 8 8 Leucine rich repeat LRR_4 PF12799.7 CBZ24669.1 - 1.6e-19 69.6 12.8 0.035 14.5 0.0 7.9 3 2 2 8 8 8 6 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 CBZ24669.1 - 0.00047 20.3 2.9 31 5.6 0.1 6.6 6 0 0 6 6 6 0 Leucine Rich Repeat LRRNT_2 PF08263.12 CBZ24669.1 - 0.0014 18.9 0.3 0.0014 18.9 0.3 2.9 3 0 0 3 3 3 1 Leucine rich repeat N-terminal domain PGAP1 PF07819.13 CBZ24669.1 - 0.03 14.0 0.1 25 4.5 0.0 3.3 1 1 2 3 3 3 0 PGAP1-like protein HERV-K_REC PF15695.5 CBZ24669.1 - 1.8 8.6 13.7 7.6 6.7 2.1 5.4 1 1 4 5 5 5 0 Rec (regulator of expression encoded by corf) of HERV-K-113 LRR_8 PF13855.6 CBZ24671.1 - 0.00012 21.8 0.0 0.18 11.6 0.0 3.1 1 1 3 4 4 4 4 Leucine rich repeat LRRNT_2 PF08263.12 CBZ24671.1 - 0.0031 17.8 1.4 0.0077 16.5 0.1 2.3 2 0 0 2 2 2 1 Leucine rich repeat N-terminal domain LRR_4 PF12799.7 CBZ24671.1 - 0.0036 17.7 0.0 1.1 9.8 0.0 3.1 2 1 2 4 4 4 1 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CBZ24672.1 - 5e-06 26.2 0.3 0.21 11.4 0.0 3.1 1 1 2 3 3 3 3 Leucine rich repeat LRR_4 PF12799.7 CBZ24672.1 - 0.0021 18.4 0.5 4 8.0 0.5 3.4 3 1 0 3 3 3 2 Leucine Rich repeats (2 copies) LRRNT_2 PF08263.12 CBZ24672.1 - 0.0048 17.2 1.4 0.011 16.0 0.1 2.4 2 0 0 2 2 2 1 Leucine rich repeat N-terminal domain Mucin PF01456.17 CBZ24672.1 - 0.7 9.9 30.9 0.078 13.0 24.4 2.2 2 0 0 2 2 2 0 Mucin-like glycoprotein DnaJ PF00226.31 CBZ24675.1 - 7.1e-12 45.3 0.0 1.2e-11 44.5 0.0 1.4 1 0 0 1 1 1 1 DnaJ domain zf-C3HC4_3 PF13920.6 CBZ24675.1 - 0.093 12.6 10.0 0.17 11.7 10.0 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) PDZ_6 PF17820.1 CBZ24676.1 - 0.02 14.7 0.0 0.063 13.1 0.0 1.8 1 0 0 1 1 1 0 PDZ domain PDZ PF00595.24 CBZ24676.1 - 0.026 14.9 0.0 0.062 13.7 0.0 1.6 1 0 0 1 1 1 0 PDZ domain PDZ_2 PF13180.6 CBZ24676.1 - 0.028 14.8 0.0 0.13 12.6 0.0 2.1 1 0 0 1 1 1 0 PDZ domain Oxidored_FMN PF00724.20 CBZ24677.1 - 1.3e-77 261.4 0.0 1.7e-77 261.0 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family His_biosynth PF00977.21 CBZ24677.1 - 0.051 13.0 0.0 0.086 12.3 0.0 1.3 1 0 0 1 1 1 0 Histidine biosynthesis protein Oxidored_FMN PF00724.20 CBZ24678.1 - 3.4e-134 447.5 0.0 2.8e-74 250.4 0.0 2.0 2 0 0 2 2 2 2 NADH:flavin oxidoreductase / NADH oxidase family TmoB PF06234.12 CBZ24678.1 - 0.075 13.1 3.9 4.3 7.5 2.0 3.0 2 1 0 2 2 2 0 Toluene-4-monooxygenase system protein B (TmoB) CSD PF00313.22 CBZ24682.1 - 0.0006 19.6 0.0 0.02 14.7 0.0 2.4 2 0 0 2 2 2 2 'Cold-shock' DNA-binding domain ABC_tran PF00005.27 CBZ24683.1 - 1.4e-11 45.0 0.0 4.9e-10 40.1 0.0 2.6 1 1 0 1 1 1 1 ABC transporter RsgA_GTPase PF03193.16 CBZ24683.1 - 0.0055 16.6 0.0 0.011 15.7 0.0 1.3 1 0 0 1 1 1 1 RsgA GTPase AAA_30 PF13604.6 CBZ24683.1 - 0.045 13.5 0.0 0.1 12.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_21 PF13304.6 CBZ24683.1 - 0.051 13.4 0.0 1.6 8.5 0.0 2.2 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 CBZ24683.1 - 0.13 12.1 2.2 0.12 12.1 0.2 2.0 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_5 PF07728.14 CBZ24683.1 - 0.15 12.0 0.0 0.34 10.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 CBZ24683.1 - 0.16 12.3 0.1 0.57 10.4 0.1 1.9 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 CBZ24683.1 - 0.19 12.1 2.6 0.16 12.4 0.3 2.0 2 0 0 2 2 2 0 AAA ATPase domain ATG16 PF08614.11 CBZ24685.1 - 0.62 10.3 2.6 1.6 8.9 0.0 2.4 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) SelP_N PF04592.14 CBZ24685.1 - 3 7.2 5.8 5.8 6.3 5.8 1.4 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Mcl1_mid PF12341.8 CBZ24686.1 - 1.2e-55 188.9 0.0 2.1e-55 188.2 0.0 1.4 1 0 0 1 1 1 1 Minichromosome loss protein, Mcl1, middle region WD40 PF00400.32 CBZ24686.1 - 0.12 13.3 1.2 13 6.8 0.1 3.5 3 0 0 3 3 3 0 WD domain, G-beta repeat SNARE_assoc PF09335.11 CBZ24687.1 - 4.2e-20 72.4 5.9 4.2e-20 72.4 5.9 1.9 2 0 0 2 2 2 1 SNARE associated Golgi protein XhlA PF10779.9 CBZ24687.1 - 0.1 12.8 0.0 0.2 11.8 0.0 1.5 1 0 0 1 1 1 0 Haemolysin XhlA FtsK_4TM PF13491.6 CBZ24687.1 - 1.6 8.4 8.6 0.5 10.1 3.9 2.3 2 1 1 3 3 3 0 4TM region of DNA translocase FtsK/SpoIIIE zf-RING_UBOX PF13445.6 CBZ24688.1 - 5.1e-08 32.8 4.4 1.6e-07 31.2 4.4 1.9 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 CBZ24688.1 - 1.6e-05 24.6 3.8 1.6e-05 24.6 3.8 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 CBZ24688.1 - 7.4e-05 22.5 7.0 7.4e-05 22.5 7.0 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 CBZ24688.1 - 0.0016 18.6 4.7 0.0016 18.6 4.7 2.5 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 CBZ24688.1 - 0.0039 17.1 7.6 0.0039 17.1 7.6 2.3 2 0 0 2 2 2 1 zinc-RING finger domain MPS2 PF17060.5 CBZ24688.1 - 0.052 12.8 0.9 0.14 11.4 0.9 1.7 1 0 0 1 1 1 0 Monopolar spindle protein 2 zf-RING_2 PF13639.6 CBZ24688.1 - 0.071 13.5 15.9 0.023 15.0 10.7 2.6 2 0 0 2 2 2 0 Ring finger domain zf-RING_6 PF14835.6 CBZ24688.1 - 0.071 13.0 7.8 0.2 11.5 7.8 1.7 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-C3HC4_3 PF13920.6 CBZ24688.1 - 0.1 12.5 16.2 0.037 13.9 12.4 2.3 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Peptidase_M1 PF01433.20 CBZ24689.1 - 6.7e-50 169.7 0.0 1.1e-49 169.0 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M1 domain Peptidase_M1_N PF17900.1 CBZ24689.1 - 7.2e-20 71.9 0.0 3.1e-14 53.6 0.0 2.3 2 0 0 2 2 2 2 Peptidase M1 N-terminal domain ERAP1_C PF11838.8 CBZ24689.1 - 7.9e-05 22.3 0.0 0.00013 21.6 0.0 1.3 1 0 0 1 1 1 1 ERAP1-like C-terminal domain zf-RanBP PF00641.18 CBZ24690.1 - 0.18 11.2 2.4 0.36 10.2 2.4 1.5 1 0 0 1 1 1 0 Zn-finger in Ran binding protein and others Evr1_Alr PF04777.13 CBZ24690.1 - 0.27 11.7 1.6 0.83 10.2 1.6 1.9 1 1 0 1 1 1 0 Erv1 / Alr family Methyltransf_25 PF13649.6 CBZ24691.1 - 5.7e-12 46.2 0.1 1.4e-11 44.9 0.1 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CBZ24691.1 - 8.2e-12 45.2 0.1 1.3e-11 44.5 0.1 1.4 1 1 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 CBZ24691.1 - 1e-11 44.8 0.0 1.6e-11 44.2 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_11 PF08241.12 CBZ24691.1 - 8.1e-09 36.0 0.0 1.8e-08 34.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 CBZ24691.1 - 6.7e-08 32.5 0.0 1e-07 31.9 0.0 1.3 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 CBZ24691.1 - 1.4e-06 28.0 0.2 2.2e-06 27.3 0.2 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_12 PF08242.12 CBZ24691.1 - 4.1e-06 27.4 0.0 9.6e-06 26.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.11 CBZ24691.1 - 1e-05 24.7 0.1 1.4e-05 24.1 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) TehB PF03848.14 CBZ24691.1 - 3.4e-05 23.3 0.4 7.6e-05 22.2 0.4 1.6 1 1 0 1 1 1 1 Tellurite resistance protein TehB CMAS PF02353.20 CBZ24691.1 - 7.1e-05 22.2 0.1 0.00011 21.6 0.1 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase PRMT5 PF05185.16 CBZ24691.1 - 0.00025 20.9 0.0 0.0004 20.3 0.0 1.3 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase Methyltransf_18 PF12847.7 CBZ24691.1 - 0.00051 20.0 0.1 0.00086 19.3 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.19 CBZ24691.1 - 0.0063 16.6 0.1 0.012 15.8 0.1 1.5 1 1 0 1 1 1 1 FtsJ-like methyltransferase PCMT PF01135.19 CBZ24691.1 - 0.015 15.1 0.0 0.021 14.6 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_32 PF13679.6 CBZ24691.1 - 0.015 15.3 0.0 0.024 14.6 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain NodS PF05401.11 CBZ24691.1 - 0.016 14.8 0.1 0.025 14.2 0.1 1.2 1 0 0 1 1 1 0 Nodulation protein S (NodS) Met_10 PF02475.16 CBZ24691.1 - 0.019 14.7 0.0 0.031 14.0 0.0 1.2 1 0 0 1 1 1 0 Met-10+ like-protein SET PF00856.28 CBZ24694.1 - 4.4e-11 43.4 0.0 1.1e-10 42.1 0.0 1.6 1 1 0 1 1 1 1 SET domain zf-MYND PF01753.18 CBZ24694.1 - 0.011 15.8 12.5 0.011 15.8 12.5 2.7 2 1 0 2 2 2 0 MYND finger TPR_2 PF07719.17 CBZ24694.1 - 0.032 14.3 1.0 0.27 11.5 0.8 2.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.6 CBZ24694.1 - 0.073 13.4 0.3 0.24 11.7 0.3 1.9 1 0 0 1 1 1 0 Tetratricopeptide repeat FAM91_C PF14648.6 CBZ24695.1 - 7e-122 407.4 0.0 4.2e-120 401.5 0.0 2.1 1 1 0 1 1 1 1 FAM91 C-terminus FAM91_N PF14647.6 CBZ24695.1 - 4e-102 341.6 0.1 5.3e-102 341.3 0.1 1.1 1 0 0 1 1 1 1 FAM91 N-terminus Vps39_2 PF10367.9 CBZ24696.1 - 2.1e-26 92.5 0.2 4.8e-26 91.3 0.2 1.7 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 Vps39_1 PF10366.9 CBZ24696.1 - 2.1e-08 34.4 0.1 4.3e-07 30.2 0.0 2.8 3 0 0 3 3 3 1 Vacuolar sorting protein 39 domain 1 Clathrin PF00637.20 CBZ24696.1 - 0.0003 20.7 0.0 0.0026 17.6 0.0 2.3 2 0 0 2 2 2 1 Region in Clathrin and VPS Rad50_zn_hook PF04423.14 CBZ24696.1 - 0.15 11.9 0.0 0.37 10.6 0.0 1.6 1 0 0 1 1 1 0 Rad50 zinc hook motif Abhydrolase_1 PF00561.20 CBZ24697.1 - 0.0034 17.1 0.0 0.011 15.3 0.0 1.8 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 CBZ24697.1 - 0.012 16.2 0.1 0.035 14.7 0.0 1.8 1 1 0 1 1 1 0 Alpha/beta hydrolase family DLH PF01738.18 CBZ24697.1 - 0.012 15.1 0.0 0.024 14.2 0.0 1.4 1 0 0 1 1 1 0 Dienelactone hydrolase family FSIP1 PF15554.6 CBZ24697.1 - 0.12 11.5 0.1 0.18 10.9 0.1 1.1 1 0 0 1 1 1 0 FSIP1 family Peptidase_S9 PF00326.21 CBZ24697.1 - 0.13 11.8 0.0 0.22 11.0 0.0 1.4 1 0 0 1 1 1 0 Prolyl oligopeptidase family WD40 PF00400.32 CBZ24699.1 - 2.9e-11 43.7 0.8 0.2 12.6 0.2 5.9 5 0 0 5 5 5 3 WD domain, G-beta repeat Nup160 PF11715.8 CBZ24699.1 - 0.013 14.2 0.0 0.093 11.3 0.0 2.3 1 1 0 1 1 1 0 Nucleoporin Nup120/160 LisH PF08513.11 CBZ24699.1 - 0.12 12.3 0.0 0.27 11.3 0.0 1.5 1 0 0 1 1 1 0 LisH PQQ PF01011.21 CBZ24699.1 - 0.76 9.8 4.0 1.2 9.2 0.2 3.0 3 0 0 3 3 3 0 PQQ enzyme repeat Prenyltransf PF01255.19 CBZ24700.1 - 9.4e-58 195.4 1.2 4.8e-55 186.5 0.2 2.1 2 0 0 2 2 2 2 Putative undecaprenyl diphosphate synthase Maf1 PF09174.10 CBZ24700.1 - 0.0047 17.1 0.0 0.0082 16.3 0.0 1.3 1 0 0 1 1 1 1 Maf1 regulator SKA2 PF16740.5 CBZ24701.1 - 0.011 15.5 0.8 0.25 11.1 0.0 2.3 1 1 1 2 2 2 0 Spindle and kinetochore-associated protein 2 Snapin_Pallidin PF14712.6 CBZ24701.1 - 0.016 15.6 0.5 0.097 13.1 0.3 2.1 2 0 0 2 2 2 0 Snapin/Pallidin DUF3086 PF11285.8 CBZ24701.1 - 0.02 14.0 0.2 0.025 13.7 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3086) Sulfolobus_pRN PF05584.11 CBZ24701.1 - 0.07 13.2 0.1 0.13 12.3 0.1 1.4 1 0 0 1 1 1 0 Sulfolobus plasmid regulatory protein Jnk-SapK_ap_N PF09744.9 CBZ24701.1 - 0.075 13.3 1.6 0.11 12.8 1.6 1.2 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 DUF4795 PF16043.5 CBZ24701.1 - 0.11 12.1 0.2 0.14 11.7 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4795) WEMBL PF05701.11 CBZ24701.1 - 0.11 11.1 0.8 0.15 10.7 0.8 1.0 1 0 0 1 1 1 0 Weak chloroplast movement under blue light Transmemb_17 PF09799.9 CBZ24701.1 - 0.12 13.0 0.0 0.2 12.3 0.0 1.3 1 0 0 1 1 1 0 Predicted membrane protein Exonuc_VII_L PF02601.15 CBZ24701.1 - 0.17 11.5 0.8 0.22 11.0 0.8 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit ACR_tran PF00873.19 CBZ24702.1 - 0.12 10.0 0.1 0.15 9.7 0.1 1.1 1 0 0 1 1 1 0 AcrB/AcrD/AcrF family SOAR PF16533.5 CBZ24702.1 - 0.13 12.3 2.0 0.19 11.8 0.5 2.1 1 1 1 2 2 2 0 STIM1 Orai1-activating region KASH_CCD PF14662.6 CBZ24702.1 - 0.22 11.4 6.7 0.085 12.7 2.9 1.9 2 0 0 2 2 2 0 Coiled-coil region of CCDC155 or KASH DUF3847 PF12958.7 CBZ24702.1 - 8.1 6.6 16.8 8.9 6.5 6.9 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF3847) RNase_HII PF01351.18 CBZ24703.1 - 1.7e-15 57.4 0.0 3.4e-11 43.4 0.0 2.2 2 0 0 2 2 2 2 Ribonuclease HII SF3b10 PF07189.11 CBZ24703.1 - 0.33 11.1 1.0 45 4.2 0.1 3.0 3 0 0 3 3 3 0 Splicing factor 3B subunit 10 (SF3b10) DNA_pol_A PF00476.20 CBZ24706.1 - 6.7e-34 117.6 0.0 2.6e-33 115.6 0.0 1.9 1 1 0 1 1 1 1 DNA polymerase family A RNase_T PF00929.24 CBZ24706.1 - 4.6e-16 59.8 0.0 1.7e-15 58.0 0.0 2.1 1 0 0 1 1 1 1 Exonuclease RNase_H_2 PF13482.6 CBZ24706.1 - 0.0055 16.7 0.0 0.034 14.1 0.0 2.3 2 0 0 2 2 2 1 RNase_H superfamily Pro_dh PF01619.18 CBZ24706.1 - 0.039 13.5 0.1 0.1 12.1 0.0 1.7 2 0 0 2 2 2 0 Proline dehydrogenase Peptidase_M32 PF02074.15 CBZ24707.1 - 4.4e-155 517.2 0.0 4.9e-155 517.0 0.0 1.0 1 0 0 1 1 1 1 Carboxypeptidase Taq (M32) metallopeptidase SURF1 PF02104.15 CBZ24709.1 - 3.9e-30 105.4 0.8 4.5e-30 105.2 0.0 1.4 2 0 0 2 2 2 1 SURF1 family DUF2939 PF11159.8 CBZ24709.1 - 0.12 12.7 0.0 0.25 11.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2939) Atg14 PF10186.9 CBZ24710.1 - 0.0026 16.9 3.0 0.0026 16.9 3.0 1.0 1 0 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 DUF4472 PF14739.6 CBZ24710.1 - 0.0046 17.7 5.1 0.0062 17.3 5.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4472) F_actin_bind PF08919.10 CBZ24710.1 - 0.0071 16.4 0.5 0.013 15.6 0.1 1.7 1 1 1 2 2 2 1 F-actin binding Spc24 PF08286.11 CBZ24710.1 - 0.022 15.0 2.0 0.028 14.6 2.0 1.3 1 0 0 1 1 1 0 Spc24 subunit of Ndc80 Exc PF07825.11 CBZ24710.1 - 0.03 14.3 0.1 0.11 12.5 0.0 1.8 2 0 0 2 2 2 0 Excisionase-like protein SOGA PF11365.8 CBZ24710.1 - 0.032 15.3 7.9 0.046 14.8 7.4 1.5 1 1 1 2 2 2 0 Protein SOGA DUF2075 PF09848.9 CBZ24710.1 - 0.033 13.4 1.5 0.038 13.2 1.5 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) TMPIT PF07851.13 CBZ24710.1 - 0.067 12.4 3.9 0.074 12.3 3.9 1.0 1 0 0 1 1 1 0 TMPIT-like protein TSC22 PF01166.18 CBZ24710.1 - 1.3 9.4 6.6 1.5 9.1 3.3 2.4 1 1 0 2 2 2 0 TSC-22/dip/bun family ZapB PF06005.12 CBZ24710.1 - 7 7.2 12.9 41 4.7 12.9 2.3 1 1 1 2 2 2 0 Cell division protein ZapB Kinesin PF00225.23 CBZ24711.1 - 2.4e-88 296.3 0.0 3.5e-88 295.7 0.0 1.3 1 0 0 1 1 1 1 Kinesin motor domain zf-TRAF PF02176.18 CBZ24711.1 - 1.8e-16 60.5 41.0 7.1e-07 29.8 8.0 5.2 4 1 1 5 5 5 4 TRAF-type zinc finger Microtub_bd PF16796.5 CBZ24711.1 - 4.6e-14 52.6 0.0 9e-14 51.7 0.0 1.4 1 0 0 1 1 1 1 Microtubule binding zf-Di19 PF05605.12 CBZ24711.1 - 0.021 15.1 1.5 0.021 15.1 1.5 4.4 3 1 2 5 5 5 0 Drought induced 19 protein (Di19), zinc-binding AAA_22 PF13401.6 CBZ24711.1 - 0.031 14.5 0.1 0.082 13.2 0.1 1.6 1 0 0 1 1 1 0 AAA domain STG PF15809.5 CBZ24713.1 - 0.037 14.1 0.6 0.073 13.1 0.6 1.4 1 0 0 1 1 1 0 Simian taste bud-specific gene product family DUF4638 PF15472.6 CBZ24713.1 - 0.094 12.4 1.0 0.16 11.7 1.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4638) cNMP_binding PF00027.29 CBZ24714.1 - 2.8e-32 110.6 0.5 4.1e-18 65.2 0.0 2.5 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain MOZ_SAS PF01853.18 CBZ24715.1 - 3.2e-22 79.0 0.0 6.1e-13 48.8 0.0 2.2 2 0 0 2 2 2 2 MOZ/SAS family zf-MYST PF17772.1 CBZ24715.1 - 0.0008 19.0 3.0 0.002 17.7 3.0 1.6 1 0 0 1 1 1 1 MYST family zinc finger domain DUF1180 PF06679.12 CBZ24715.1 - 1.5 9.2 11.0 0.22 11.9 2.9 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1180) TPR_12 PF13424.6 CBZ24716.1 - 6.4e-10 39.2 22.3 2.7e-06 27.6 0.1 5.1 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_2 PF07719.17 CBZ24716.1 - 7.1e-06 25.7 8.8 0.27 11.5 0.1 4.9 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_10 PF13374.6 CBZ24716.1 - 0.00045 20.0 12.9 2 8.4 0.0 6.0 5 1 1 6 6 6 2 Tetratricopeptide repeat TPR_8 PF13181.6 CBZ24716.1 - 0.0018 18.3 1.9 13 6.3 0.0 4.3 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_1 PF00515.28 CBZ24716.1 - 0.01 15.7 1.4 5.1 7.1 0.0 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat Foie-gras_1 PF11817.8 CBZ24716.1 - 0.014 15.0 0.1 3.7 7.1 0.0 2.4 2 0 0 2 2 2 0 Foie gras liver health family 1 TPR_16 PF13432.6 CBZ24716.1 - 0.3 11.8 14.9 3.5 8.4 0.1 5.3 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_7 PF13176.6 CBZ24716.1 - 2.5 8.3 9.5 1.3 9.2 0.1 4.4 4 1 0 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.6 CBZ24716.1 - 4.6 8.3 13.8 62 4.8 0.0 5.2 4 2 1 5 5 5 0 Tetratricopeptide repeat Reprolysin_3 PF13582.6 CBZ24717.1 - 0.095 13.2 0.1 0.17 12.4 0.1 1.4 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Lipase_3 PF01764.25 CBZ24718.1 - 7.3e-15 55.1 0.0 1.2e-14 54.4 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) Lipase_3 PF01764.25 CBZ24719.1 - 7.1e-15 55.1 0.0 1.2e-14 54.4 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) Ras PF00071.22 CBZ24720.1 - 4.6e-53 179.1 0.3 5.6e-53 178.9 0.3 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CBZ24720.1 - 5.4e-36 123.4 0.1 8e-36 122.9 0.1 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CBZ24720.1 - 2.8e-13 49.7 0.0 3.7e-13 49.3 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 CBZ24720.1 - 1.6e-08 34.2 0.1 2e-08 33.9 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 CBZ24720.1 - 1.2e-06 28.5 0.4 0.0019 18.1 0.1 2.2 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 CBZ24720.1 - 3.6e-06 27.0 0.0 6.2e-06 26.3 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 CBZ24720.1 - 2.3e-05 24.9 0.0 2.8e-05 24.6 0.0 1.3 1 1 0 1 1 1 1 AAA ATPase domain TsaE PF02367.17 CBZ24720.1 - 0.0014 18.6 0.0 0.0022 18.0 0.0 1.4 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_22 PF13401.6 CBZ24720.1 - 0.0014 18.9 0.0 0.0027 18.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain NACHT PF05729.12 CBZ24720.1 - 0.002 18.0 0.0 0.0037 17.2 0.0 1.4 1 0 0 1 1 1 1 NACHT domain AAA_7 PF12775.7 CBZ24720.1 - 0.003 17.1 0.1 0.0052 16.3 0.1 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_5 PF07728.14 CBZ24720.1 - 0.0055 16.7 0.0 0.0096 15.9 0.0 1.7 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) GTP_EFTU PF00009.27 CBZ24720.1 - 0.01 15.4 0.0 0.09 12.3 0.0 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 CBZ24720.1 - 0.021 14.3 0.0 0.027 13.9 0.0 1.3 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit FeoB_N PF02421.18 CBZ24720.1 - 0.021 14.3 0.0 0.16 11.5 0.0 2.0 1 1 0 1 1 1 0 Ferrous iron transport protein B G-alpha PF00503.20 CBZ24720.1 - 0.023 13.9 0.6 0.081 12.1 0.3 1.9 1 1 1 2 2 2 0 G-protein alpha subunit RNA_helicase PF00910.22 CBZ24720.1 - 0.025 15.0 0.1 0.041 14.3 0.1 1.6 1 1 0 1 1 1 0 RNA helicase AAA_24 PF13479.6 CBZ24720.1 - 0.025 14.3 0.0 0.04 13.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain DUF815 PF05673.13 CBZ24720.1 - 0.04 13.1 0.2 0.07 12.3 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) DAP3 PF10236.9 CBZ24720.1 - 0.041 13.0 0.1 0.076 12.2 0.1 1.3 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 Sigma54_activat PF00158.26 CBZ24720.1 - 0.044 13.5 0.0 0.075 12.7 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain Rad17 PF03215.15 CBZ24720.1 - 0.047 13.6 0.0 0.09 12.7 0.0 1.5 1 0 0 1 1 1 0 Rad17 P-loop domain VirE PF05272.11 CBZ24720.1 - 0.056 13.2 0.0 0.096 12.4 0.0 1.4 1 0 0 1 1 1 0 Virulence-associated protein E ABC_tran PF00005.27 CBZ24720.1 - 0.074 13.6 0.0 0.15 12.6 0.0 1.5 1 0 0 1 1 1 0 ABC transporter Septin PF00735.18 CBZ24720.1 - 0.076 12.3 0.0 0.1 11.8 0.0 1.2 1 0 0 1 1 1 0 Septin Torsin PF06309.11 CBZ24720.1 - 0.082 13.0 0.1 0.14 12.3 0.1 1.4 1 0 0 1 1 1 0 Torsin AAA_18 PF13238.6 CBZ24720.1 - 0.11 13.1 0.1 0.13 12.8 0.1 1.6 1 1 0 1 1 1 0 AAA domain AAA_33 PF13671.6 CBZ24720.1 - 0.11 12.7 0.1 0.19 11.9 0.1 1.7 1 1 0 1 1 1 0 AAA domain AAA_14 PF13173.6 CBZ24720.1 - 0.15 12.1 0.0 0.23 11.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain zf-C3HC4_3 PF13920.6 CBZ24721.1 - 1.3e-05 24.9 9.6 3e-05 23.8 9.6 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CBZ24721.1 - 5.9e-05 23.0 9.1 0.00013 21.9 9.1 1.6 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 CBZ24721.1 - 0.00068 19.5 10.5 0.0014 18.4 10.5 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 ERM PF00769.19 CBZ24721.1 - 0.0088 15.9 5.1 0.013 15.3 5.1 1.1 1 0 0 1 1 1 1 Ezrin/radixin/moesin family HIP1_clath_bdg PF16515.5 CBZ24721.1 - 0.011 16.3 4.8 0.011 16.3 4.8 1.7 1 1 1 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 DUF1848 PF08902.11 CBZ24721.1 - 0.013 15.3 0.5 0.018 14.8 0.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1848) zf-C3HC4_2 PF13923.6 CBZ24721.1 - 0.031 14.1 9.7 0.07 13.0 9.7 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CBZ24721.1 - 0.035 14.0 9.0 0.074 12.9 9.0 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CBZ24721.1 - 0.05 13.9 10.8 0.1 13.0 10.8 1.5 1 0 0 1 1 1 0 Ring finger domain zf-P11 PF03854.14 CBZ24721.1 - 0.06 13.0 9.2 0.11 12.1 9.2 1.4 1 0 0 1 1 1 0 P-11 zinc finger AATF-Che1 PF13339.6 CBZ24721.1 - 0.081 13.6 0.9 0.14 12.8 0.9 1.3 1 0 0 1 1 1 0 Apoptosis antagonizing transcription factor DUF4200 PF13863.6 CBZ24721.1 - 0.2 12.0 2.2 0.31 11.4 2.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) Peptidase_S46 PF10459.9 CBZ24721.1 - 0.2 10.2 3.4 0.26 9.9 3.4 1.0 1 0 0 1 1 1 0 Peptidase S46 CENP-F_leu_zip PF10473.9 CBZ24721.1 - 0.2 11.6 2.0 0.3 11.1 2.0 1.2 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 YabA PF06156.13 CBZ24721.1 - 0.34 11.6 1.6 0.71 10.5 1.6 1.5 1 0 0 1 1 1 0 Initiation control protein YabA Tho2 PF11262.8 CBZ24721.1 - 0.45 9.7 2.2 0.6 9.3 2.2 1.1 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 XRN_M PF17846.1 CBZ24721.1 - 0.5 9.3 1.3 0.67 8.8 1.3 1.1 1 0 0 1 1 1 0 Xrn1 helical domain zf-RING_4 PF14570.6 CBZ24721.1 - 0.52 10.1 8.7 0.96 9.3 8.7 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Mod_r PF07200.13 CBZ24721.1 - 1.3 9.1 5.6 2.1 8.5 5.6 1.3 1 0 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein zf-RING_6 PF14835.6 CBZ24721.1 - 3 7.8 8.4 1.4 8.8 5.2 2.1 2 1 0 2 2 2 0 zf-RING of BARD1-type protein ZapB PF06005.12 CBZ24721.1 - 8.1 7.0 7.2 2.8 8.5 2.4 2.1 1 1 1 2 2 2 0 Cell division protein ZapB DUF4200 PF13863.6 CBZ24722.1 - 6.8e-24 84.5 26.9 6.8e-24 84.5 26.9 3.0 3 0 0 3 3 3 2 Domain of unknown function (DUF4200) DUF3918 PF13056.6 CBZ24722.1 - 0.058 13.0 0.2 0.18 11.5 0.2 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3918) TACC_C PF05010.14 CBZ24722.1 - 1.3 8.8 39.2 0.3 10.8 30.9 2.4 1 1 0 2 2 2 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal Acetyltransf_1 PF00583.25 CBZ24724.1 - 6.8e-15 55.3 0.1 1.5e-14 54.2 0.0 1.6 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family FR47 PF08445.10 CBZ24724.1 - 2.6e-07 30.5 0.0 5.8e-07 29.4 0.0 1.6 2 0 0 2 2 2 1 FR47-like protein Acetyltransf_10 PF13673.7 CBZ24724.1 - 3.6e-07 30.1 0.2 6.5e-07 29.3 0.2 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 CBZ24724.1 - 9.8e-06 25.9 0.1 1.9e-05 25.0 0.1 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 CBZ24724.1 - 0.013 15.7 0.1 0.019 15.1 0.1 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain DUF5596 PF18082.1 CBZ24724.1 - 0.036 13.9 0.0 0.087 12.7 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF5596) Acetyltransf_15 PF17013.5 CBZ24724.1 - 0.041 13.4 0.1 0.048 13.1 0.1 1.2 1 0 0 1 1 1 0 Putative acetyl-transferase Acetyltransf_9 PF13527.7 CBZ24724.1 - 0.049 13.7 0.1 0.049 13.7 0.1 1.7 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain TMEM108 PF15759.5 CBZ24724.1 - 0.12 11.3 0.1 0.17 10.9 0.1 1.1 1 0 0 1 1 1 0 TMEM108 family Tubulin PF00091.25 CBZ24726.1 - 2.8e-65 220.2 0.0 3.9e-65 219.7 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 CBZ24726.1 - 5.8e-50 168.7 0.0 9.6e-50 168.0 0.0 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 CBZ24726.1 - 0.01 15.5 0.0 0.022 14.4 0.0 1.5 1 0 0 1 1 1 0 Tubulin domain Tubulin PF00091.25 CBZ24727.1 - 2.8e-65 220.2 0.0 3.9e-65 219.7 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 CBZ24727.1 - 5.8e-50 168.7 0.0 9.6e-50 168.0 0.0 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 CBZ24727.1 - 0.01 15.5 0.0 0.022 14.4 0.0 1.5 1 0 0 1 1 1 0 Tubulin domain Nipped-B_C PF12830.7 CBZ24728.1 - 1.7e-24 86.8 0.0 6e-24 85.0 0.0 2.0 1 0 0 1 1 1 1 Sister chromatid cohesion C-terminus AMP-binding PF00501.28 CBZ24730.1 - 1.2e-58 198.7 0.2 1.8e-58 198.1 0.2 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 CBZ24730.1 - 3.8e-05 24.6 0.6 0.00038 21.4 0.6 2.7 1 1 0 1 1 1 1 AMP-binding enzyme C-terminal domain FeoA PF04023.14 CBZ24730.1 - 0.034 14.4 0.0 0.11 12.7 0.0 1.9 1 0 0 1 1 1 0 FeoA domain Radial_spoke PF04712.12 CBZ24731.1 - 4.5e-120 401.9 21.1 5.6e-88 296.0 9.4 2.6 1 1 1 2 2 2 2 Radial spokehead-like protein Pkinase PF00069.25 CBZ24732.1 - 4.3e-80 268.9 0.0 7.7e-80 268.0 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ24732.1 - 1.6e-45 155.4 0.0 3.3e-45 154.4 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase HEAT_EZ PF13513.6 CBZ24732.1 - 8.7e-11 42.1 3.2 9.8e-06 26.0 0.1 5.1 4 1 1 5 5 5 3 HEAT-like repeat Arm PF00514.23 CBZ24732.1 - 9.2e-11 41.4 4.6 0.0001 22.2 0.0 6.4 6 0 0 6 6 6 2 Armadillo/beta-catenin-like repeat HEAT PF02985.22 CBZ24732.1 - 4e-08 32.8 1.8 1.4 9.3 0.0 5.5 5 0 0 5 5 4 2 HEAT repeat HEAT_2 PF13646.6 CBZ24732.1 - 5.9e-07 29.8 0.1 1.7e-05 25.1 0.2 3.1 1 1 1 2 2 2 2 HEAT repeats Kinase-like PF14531.6 CBZ24732.1 - 9.1e-06 25.2 0.0 0.00014 21.3 0.0 2.1 1 1 1 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 CBZ24732.1 - 7.9e-05 21.6 0.0 0.00017 20.5 0.0 1.5 1 0 0 1 1 1 1 Fungal protein kinase RIO1 PF01163.22 CBZ24732.1 - 0.00014 21.5 1.1 0.0021 17.7 0.1 2.2 1 1 0 2 2 2 1 RIO1 family FTA2 PF13095.6 CBZ24732.1 - 0.0013 18.4 1.3 0.31 10.6 0.1 2.3 1 1 1 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 Haspin_kinase PF12330.8 CBZ24732.1 - 0.0038 16.2 0.1 0.0067 15.4 0.1 1.3 1 0 0 1 1 1 1 Haspin like kinase domain YrbL-PhoP_reg PF10707.9 CBZ24732.1 - 0.0066 16.0 1.1 0.0088 15.6 0.2 1.7 2 0 0 2 2 2 1 PhoP regulatory network protein YrbL APH PF01636.23 CBZ24732.1 - 0.0083 16.1 0.0 0.027 14.4 0.0 1.8 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 CBZ24732.1 - 0.01 15.2 0.0 0.019 14.4 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.11 CBZ24732.1 - 0.015 14.4 0.0 0.032 13.3 0.0 1.5 1 0 0 1 1 1 0 Seadornavirus VP7 DUF3361 PF11841.8 CBZ24732.1 - 0.016 15.2 0.0 8.5 6.3 0.0 3.0 1 1 0 2 2 2 0 Domain of unknown function (DUF3361) Urb2 PF10441.9 CBZ24732.1 - 0.023 14.6 0.1 0.18 11.7 0.0 2.4 2 0 0 2 2 2 0 Urb2/Npa2 family ABC1 PF03109.16 CBZ24732.1 - 0.028 14.6 0.1 0.22 11.7 0.0 2.3 1 1 1 2 2 2 0 ABC1 family WAPL PF07814.13 CBZ24732.1 - 0.076 11.8 0.5 0.66 8.7 0.6 2.3 1 1 0 1 1 1 0 Wings apart-like protein regulation of heterochromatin Cnd1 PF12717.7 CBZ24732.1 - 0.081 13.0 2.7 0.35 10.9 0.0 3.2 3 1 1 4 4 4 0 non-SMC mitotic condensation complex subunit 1 PIP49_C PF12260.8 CBZ24732.1 - 0.1 12.2 0.0 0.23 11.1 0.0 1.5 1 0 0 1 1 1 0 Protein-kinase domain of FAM69 Alba PF01918.21 CBZ24733.1 - 4.9e-16 58.3 1.1 7e-16 57.8 0.4 1.6 2 0 0 2 2 2 1 Alba Rpp20 PF12328.8 CBZ24733.1 - 0.00081 19.4 1.7 0.00091 19.2 1.7 1.1 1 0 0 1 1 1 1 Rpp20 subunit of nuclear RNase MRP and P C2 PF00168.30 CBZ24734.1 - 0.00089 19.5 0.1 0.0032 17.7 0.0 2.0 2 0 0 2 2 2 1 C2 domain TMF_TATA_bd PF12325.8 CBZ24736.1 - 2.6e-07 30.8 57.5 1.5e-06 28.4 1.5 5.6 2 1 3 5 5 5 2 TATA element modulatory factor 1 TATA binding Filament PF00038.21 CBZ24736.1 - 7.7e-06 25.7 51.7 0.0012 18.6 7.0 5.1 2 1 3 5 5 5 3 Intermediate filament protein CENP-F_leu_zip PF10473.9 CBZ24736.1 - 7e-05 22.9 54.2 0.34 10.9 13.5 6.1 3 1 1 5 5 5 4 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Tektin PF03148.14 CBZ24736.1 - 0.00022 20.1 16.8 0.00022 20.1 16.8 4.3 2 1 1 4 4 4 1 Tektin family SHE3 PF17078.5 CBZ24736.1 - 0.00047 20.0 10.6 0.00047 20.0 10.6 3.6 2 1 2 4 4 3 1 SWI5-dependent HO expression protein 3 RILP PF11461.8 CBZ24736.1 - 0.004 17.3 2.3 0.004 17.3 2.3 3.1 2 0 0 2 2 2 1 Rab interacting lysosomal protein Rootletin PF15035.6 CBZ24736.1 - 0.013 15.5 10.7 0.013 15.5 10.7 5.8 2 1 3 5 5 5 0 Ciliary rootlet component, centrosome cohesion DUF2353 PF09789.9 CBZ24736.1 - 0.015 14.7 46.4 0.067 12.5 17.9 4.1 2 1 2 4 4 4 0 Uncharacterized coiled-coil protein (DUF2353) TPR_MLP1_2 PF07926.12 CBZ24736.1 - 0.016 15.3 14.4 0.016 15.3 14.4 6.4 3 2 1 5 5 5 0 TPR/MLP1/MLP2-like protein BST2 PF16716.5 CBZ24736.1 - 0.019 15.5 3.1 0.019 15.5 3.1 6.5 3 2 4 7 7 7 0 Bone marrow stromal antigen 2 GAS PF13851.6 CBZ24736.1 - 0.058 12.7 54.9 0.15 11.4 1.3 4.6 2 1 2 4 4 4 0 Growth-arrest specific micro-tubule binding DivIC PF04977.15 CBZ24736.1 - 0.1 12.4 0.2 0.1 12.4 0.2 8.0 3 2 4 8 8 8 0 Septum formation initiator ATG16 PF08614.11 CBZ24736.1 - 0.18 12.0 68.0 0.26 11.5 17.3 5.6 2 2 3 5 5 5 0 Autophagy protein 16 (ATG16) MscS_porin PF12795.7 CBZ24736.1 - 0.19 11.2 61.6 0.014 15.0 8.8 5.0 2 1 2 4 4 4 0 Mechanosensitive ion channel porin domain Uso1_p115_C PF04871.13 CBZ24736.1 - 0.21 11.9 59.4 0.15 12.4 2.0 5.6 2 1 3 5 5 5 0 Uso1 / p115 like vesicle tethering protein, C terminal region Baculo_PEP_C PF04513.12 CBZ24736.1 - 0.27 11.3 21.0 2 8.5 5.5 4.0 2 1 1 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus BCL_N PF04714.13 CBZ24736.1 - 0.27 11.3 9.4 7.2 6.8 0.0 3.6 3 0 0 3 3 3 0 BCL7, N-terminal conserver region UCH_C PF18031.1 CBZ24736.1 - 0.29 11.1 0.1 0.29 11.1 0.1 3.8 3 0 0 3 3 3 0 Ubiquitin carboxyl-terminal hydrolases Spc7 PF08317.11 CBZ24736.1 - 0.46 9.3 53.2 0.0078 15.1 19.6 4.1 2 1 2 4 4 4 0 Spc7 kinetochore protein DUF1664 PF07889.12 CBZ24736.1 - 0.47 10.5 30.2 6.4 6.8 4.2 5.3 2 1 2 6 6 6 0 Protein of unknown function (DUF1664) Fib_alpha PF08702.10 CBZ24736.1 - 0.68 10.1 33.1 1.9 8.7 4.3 4.9 1 1 5 6 6 6 0 Fibrinogen alpha/beta chain family FlaC_arch PF05377.11 CBZ24736.1 - 0.69 10.3 30.4 4.6 7.7 0.1 7.7 5 3 1 7 7 7 0 Flagella accessory protein C (FlaC) Fez1 PF06818.15 CBZ24736.1 - 1 9.8 53.4 9.8 6.6 0.9 4.2 1 1 3 4 4 4 0 Fez1 NPV_P10 PF05531.12 CBZ24736.1 - 1.1 9.7 19.6 5 7.7 1.5 5.3 4 2 1 5 5 4 0 Nucleopolyhedrovirus P10 protein Seryl_tRNA_N PF02403.22 CBZ24736.1 - 1.6 9.0 39.5 1.6 9.0 7.4 6.1 2 1 2 5 5 5 0 Seryl-tRNA synthetase N-terminal domain FAA_hydrolase_N PF09298.11 CBZ24736.1 - 1.6 8.9 0.0 1.6 8.9 0.0 3.9 2 1 3 5 5 5 0 Fumarylacetoacetase N-terminal Occludin_ELL PF07303.13 CBZ24736.1 - 2.8 8.7 27.4 0.59 10.9 1.8 5.3 3 1 3 6 6 6 0 Occludin homology domain Pox_A_type_inc PF04508.12 CBZ24736.1 - 4.3 7.4 0.0 4.3 7.4 0.0 4.9 5 0 0 5 5 4 0 Viral A-type inclusion protein repeat TSC22 PF01166.18 CBZ24736.1 - 4.5 7.6 33.1 6.7 7.1 0.2 6.9 5 2 2 7 7 6 0 TSC-22/dip/bun family DUF2703 PF10865.8 CBZ24736.1 - 4.7 7.4 8.0 2.7 8.2 0.3 3.8 4 1 0 4 4 4 0 Domain of unknown function (DUF2703) DUF4407 PF14362.6 CBZ24736.1 - 6.5 6.0 45.2 1.4 8.2 18.1 3.8 1 1 2 3 3 3 0 Domain of unknown function (DUF4407) His_Phos_1 PF00300.22 CBZ24737.1 - 0.0044 16.7 0.0 2.1 8.0 0.0 2.5 2 0 0 2 2 2 2 Histidine phosphatase superfamily (branch 1) FluMu_N PF17891.1 CBZ24737.1 - 0.14 12.0 0.0 0.37 10.6 0.0 1.6 1 0 0 1 1 1 0 Mu-like prophage FluMu N-terminal domain Sec63 PF02889.16 CBZ24738.1 - 2.5e-143 475.8 2.8 1.8e-81 273.1 1.0 2.5 2 0 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.29 CBZ24738.1 - 4.1e-51 173.2 0.0 6.8e-27 94.3 0.1 2.6 2 0 0 2 2 2 2 DEAD/DEAH box helicase ResIII PF04851.15 CBZ24738.1 - 1.3e-27 96.9 0.0 1.2e-15 57.9 0.0 2.4 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit Helicase_C PF00271.31 CBZ24738.1 - 2.3e-16 60.1 0.0 1.8e-07 31.5 0.0 4.1 3 2 0 3 3 3 2 Helicase conserved C-terminal domain AAA_30 PF13604.6 CBZ24738.1 - 2.4e-09 37.2 0.0 0.00047 19.9 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.6 CBZ24738.1 - 2.5e-06 27.9 2.5 0.00093 19.6 0.1 3.1 3 0 0 3 3 3 2 AAA domain AAA_22 PF13401.6 CBZ24738.1 - 5.8e-05 23.4 1.7 0.0092 16.3 0.0 3.7 3 2 0 3 3 2 1 AAA domain T2SSE PF00437.20 CBZ24738.1 - 0.0032 16.6 0.0 2.3 7.2 0.0 2.6 2 0 0 2 2 2 2 Type II/IV secretion system protein DUF2075 PF09848.9 CBZ24738.1 - 0.0038 16.5 0.0 0.0092 15.2 0.0 1.6 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) PhoH PF02562.16 CBZ24738.1 - 0.016 14.7 0.1 0.37 10.2 0.0 2.3 2 0 0 2 2 2 0 PhoH-like protein TniB PF05621.11 CBZ24738.1 - 0.028 13.8 0.2 1.4 8.3 0.0 3.1 3 0 0 3 3 3 0 Bacterial TniB protein AAA_7 PF12775.7 CBZ24738.1 - 0.066 12.7 0.2 3.8 7.0 0.1 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region Ccdc124 PF06244.12 CBZ24740.1 - 1.7e-24 86.8 16.4 1.3e-23 83.9 16.4 2.3 1 1 0 1 1 1 1 Coiled-coil domain-containing protein 124 /Oxs1 HMG_box PF00505.19 CBZ24740.1 - 0.046 14.2 0.5 0.046 14.2 0.5 3.2 2 1 1 3 3 3 0 HMG (high mobility group) box DUF3435 PF11917.8 CBZ24740.1 - 0.55 9.1 12.9 0.85 8.5 12.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3435) F-protein PF00469.20 CBZ24740.1 - 0.63 9.6 7.0 1.1 8.8 7.0 1.4 1 0 0 1 1 1 0 Negative factor, (F-Protein) or Nef PA26 PF04636.13 CBZ24740.1 - 1.8 7.4 8.3 2.5 6.9 8.3 1.1 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) DUF3464 PF11947.8 CBZ24740.1 - 3.8 7.2 10.2 7.6 6.3 10.2 1.6 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 K_channel_TID PF07941.11 CBZ24740.1 - 8.3 6.9 7.8 2.7 8.5 1.6 2.6 2 0 0 2 2 2 0 Potassium channel Kv1.4 tandem inactivation domain FCH PF00611.23 CBZ24741.1 - 0.025 14.9 8.3 0.68 10.3 0.5 3.2 2 0 0 2 2 2 0 Fes/CIP4, and EFC/F-BAR homology domain HAD_SAK_2 PF18143.1 CBZ24741.1 - 0.53 10.6 4.5 0.25 11.7 0.4 2.6 2 1 0 2 2 2 0 HAD domain in Swiss Army Knife RNA repair proteins DUF179 PF02622.15 CBZ24743.1 - 5.1e-19 68.8 0.0 1e-18 67.8 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized ACR, COG1678 Ribosomal_L18 PF17135.4 CBZ24744.1 - 2.2e-74 248.9 3.7 2.6e-74 248.7 3.7 1.0 1 0 0 1 1 1 1 Ribosomal protein 60S L18 and 50S L18e Ribosomal_L27A PF00828.19 CBZ24744.1 - 0.00014 22.5 0.1 0.0005 20.8 0.1 2.0 1 1 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A Ribosomal_L7Ae PF01248.26 CBZ24745.1 - 1.9e-22 78.8 1.4 2.5e-22 78.4 1.4 1.2 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Atg14 PF10186.9 CBZ24746.1 - 1.8 7.5 5.3 2 7.4 0.1 2.2 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 MCU PF04678.13 CBZ24748.1 - 3.7e-11 43.4 0.1 5e-11 43.0 0.1 1.3 1 0 0 1 1 1 1 Mitochondrial calcium uniporter Acetyltransf_10 PF13673.7 CBZ24749.1 - 4.2e-08 33.2 0.0 9e-08 32.1 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 CBZ24749.1 - 5.5e-06 26.6 0.0 9e-06 25.9 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 CBZ24749.1 - 0.00057 20.3 0.0 0.0011 19.4 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain NAD_binding_7 PF13241.6 CBZ24750.1 - 0.45 11.0 3.8 13 6.2 0.6 2.3 1 1 1 2 2 2 0 Putative NAD(P)-binding SUIM_assoc PF16619.5 CBZ24750.1 - 8.2 6.6 8.7 1.5 8.9 2.0 2.7 2 1 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 DUF4061 PF13270.6 CBZ24751.1 - 0.042 14.2 0.1 0.11 12.9 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4061) HEAT_EZ PF13513.6 CBZ24752.1 - 0.01 16.3 0.5 0.01 16.3 0.5 4.2 4 0 0 4 4 4 0 HEAT-like repeat Cse1 PF08506.10 CBZ24752.1 - 0.02 13.7 0.0 0.057 12.2 0.0 1.7 2 0 0 2 2 2 0 Cse1 HEAT PF02985.22 CBZ24752.1 - 0.059 13.6 1.7 0.88 10.0 0.5 3.9 2 0 0 2 2 2 0 HEAT repeat Xpo1 PF08389.12 CBZ24752.1 - 0.11 12.6 0.5 0.91 9.6 0.0 2.7 3 0 0 3 3 3 0 Exportin 1-like protein SDA1 PF05285.12 CBZ24752.1 - 0.64 9.4 13.6 0.95 8.8 13.6 1.1 1 0 0 1 1 1 0 SDA1 BSP_II PF05432.11 CBZ24752.1 - 1.8 8.2 12.3 3 7.4 12.3 1.2 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) TFB6 PF17110.5 CBZ24752.1 - 2.1 8.1 5.2 11 5.7 0.0 2.6 2 0 0 2 2 2 0 Subunit 11 of the general transcription factor TFIIH BUD22 PF09073.10 CBZ24752.1 - 5.4 6.3 12.4 8.3 5.6 12.4 1.2 1 0 0 1 1 1 0 BUD22 DHHC PF01529.20 CBZ24753.1 - 2.2e-25 89.3 13.9 2.2e-25 89.3 13.9 2.3 2 1 1 3 3 3 1 DHHC palmitoyltransferase U-box PF04564.15 CBZ24754.1 - 1.2e-05 25.4 0.0 2.6e-05 24.3 0.0 1.5 1 0 0 1 1 1 1 U-box domain Lectin_leg-like PF03388.13 CBZ24755.1 - 1.8e-47 161.6 0.0 3e-47 160.9 0.0 1.3 1 0 0 1 1 1 1 Legume-like lectin family Bact_lectin PF18483.1 CBZ24755.1 - 6.4e-11 42.6 6.3 1.2e-10 41.7 0.0 2.1 2 0 0 2 2 2 1 Bacterial lectin TFIIA PF03153.13 CBZ24755.1 - 5.6e-06 26.6 41.6 7e-06 26.3 41.6 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Endostatin PF06482.11 CBZ24755.1 - 0.3 10.5 17.3 0.46 9.9 17.3 1.3 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin Hid1 PF12722.7 CBZ24755.1 - 0.43 8.6 18.2 0.54 8.3 18.2 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF908 PF06012.12 CBZ24755.1 - 0.83 9.0 15.1 1.1 8.6 15.1 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) ASD2 PF08687.11 CBZ24755.1 - 1 8.8 24.7 1.5 8.3 24.7 1.2 1 0 0 1 1 1 0 Apx/Shroom domain ASD2 GAGA_bind PF06217.12 CBZ24755.1 - 1.3 9.3 18.9 1.7 8.9 18.9 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family Pox_A_type_inc PF04508.12 CBZ24755.1 - 1.6 8.7 6.4 3.1 7.8 6.4 1.5 1 0 0 1 1 1 0 Viral A-type inclusion protein repeat DUF1387 PF07139.11 CBZ24755.1 - 1.6 8.4 20.9 2.3 7.9 20.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1387) V_ATPase_I PF01496.19 CBZ24755.1 - 1.7 6.5 20.0 2.2 6.1 20.0 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Presenilin PF01080.17 CBZ24755.1 - 1.7 7.3 27.9 2.4 6.8 27.9 1.2 1 0 0 1 1 1 0 Presenilin FAM60A PF15396.6 CBZ24755.1 - 2.5 8.0 13.4 4 7.4 13.4 1.4 1 0 0 1 1 1 0 Protein Family FAM60A eIF-3_zeta PF05091.12 CBZ24755.1 - 3.3 6.6 25.1 5.5 5.8 25.1 1.4 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Neur_chan_memb PF02932.16 CBZ24755.1 - 4.1 7.4 16.2 6.8 6.7 16.2 1.4 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region PAT1 PF09770.9 CBZ24755.1 - 6.9 4.8 43.4 9 4.4 43.4 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Peptidase_M24 PF00557.24 CBZ24756.1 - 9e-14 51.7 0.9 3.9e-12 46.3 0.4 2.8 2 1 1 3 3 3 2 Metallopeptidase family M24 DUF4603 PF15376.6 CBZ24756.1 - 7.2 3.9 11.0 9.9 3.4 11.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4603) PSP1 PF04468.12 CBZ24757.1 - 1.6e-20 73.2 0.0 2.9e-20 72.3 0.0 1.5 1 0 0 1 1 1 1 PSP1 C-terminal conserved region Kinesin PF00225.23 CBZ24758.1 - 7.3e-34 117.2 0.0 3.7e-09 36.0 0.0 5.1 4 1 0 4 4 4 4 Kinesin motor domain Microtub_bd PF16796.5 CBZ24758.1 - 7.2e-07 29.3 0.0 1.2e-05 25.3 0.0 2.4 2 1 0 2 2 2 1 Microtubule binding Kisspeptin PF15152.6 CBZ24758.1 - 0.18 12.6 6.7 15 6.5 0.4 4.2 2 1 0 2 2 2 0 Kisspeptin ArfGap PF01412.18 CBZ24759.1 - 5.8e-29 100.5 0.1 9.9e-29 99.8 0.1 1.3 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf ADH_zinc_N PF00107.26 CBZ24760.1 - 9.4e-14 51.5 0.0 1.9e-13 50.5 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 CBZ24760.1 - 2.5e-10 40.2 0.0 1.1e-09 38.2 0.0 1.9 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 CBZ24760.1 - 1.4e-08 35.9 0.0 2.8e-08 34.9 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ubiquitin PF00240.23 CBZ24761.1 - 4.3e-09 36.0 0.0 9.1e-09 34.9 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin family DUF2407 PF10302.9 CBZ24761.1 - 0.0026 18.3 0.1 0.042 14.4 0.0 2.7 2 0 0 2 2 2 1 DUF2407 ubiquitin-like domain Rad60-SLD PF11976.8 CBZ24761.1 - 0.0028 17.5 0.0 0.0068 16.2 0.0 1.7 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Rad60-SLD_2 PF13881.6 CBZ24761.1 - 0.0039 17.3 1.5 0.054 13.6 0.0 3.2 3 0 0 3 3 3 1 Ubiquitin-2 like Rad60 SUMO-like PrmC_N PF17827.1 CBZ24761.1 - 0.085 13.5 1.5 9.3 6.9 0.0 2.8 2 1 0 2 2 2 0 PrmC N-terminal domain Ubiquitin_2 PF14560.6 CBZ24761.1 - 0.12 12.9 0.0 0.35 11.4 0.0 1.7 1 0 0 1 1 1 0 Ubiquitin-like domain RAB3GAP2_N PF14655.6 CBZ24761.1 - 3.9 6.6 7.4 0.48 9.6 2.3 2.0 2 0 0 2 2 2 0 Rab3 GTPase-activating protein regulatory subunit N-terminus Anoctamin PF04547.12 CBZ24762.1 - 1.2e-75 255.1 0.0 1.5e-75 254.7 0.0 1.1 1 0 0 1 1 1 1 Calcium-activated chloride channel DUF3377 PF11857.8 CBZ24762.1 - 0.046 13.6 0.3 0.11 12.4 0.3 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3377) C2 PF00168.30 CBZ24764.1 - 1.3e-20 73.6 0.0 2.4e-20 72.7 0.0 1.5 1 0 0 1 1 1 1 C2 domain DSPc PF00782.20 CBZ24765.1 - 2.4e-07 30.6 0.1 4.6e-07 29.7 0.1 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Pkinase PF00069.25 CBZ24766.1 - 2.5e-40 138.5 0.0 4.8e-34 117.9 0.0 3.1 2 1 1 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ24766.1 - 1.7e-16 60.3 0.0 1.8e-15 57.0 0.0 2.5 2 1 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 CBZ24766.1 - 0.0001 21.7 0.0 0.00023 20.6 0.0 1.5 1 0 0 1 1 1 1 Kinase-like CTU2 PF10288.9 CBZ24767.1 - 0.019 15.2 1.4 0.019 15.2 1.4 2.4 2 1 0 2 2 2 0 Cytoplasmic tRNA 2-thiolation protein 2 DUF883 PF05957.13 CBZ24767.1 - 0.13 12.9 2.6 1.8 9.2 0.3 2.9 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) NUDE_C PF04880.13 CBZ24768.1 - 9.5 6.7 12.3 0.7 10.4 7.3 1.6 2 0 0 2 2 2 0 NUDE protein, C-terminal conserved region Complex1_LYR_2 PF13233.6 CBZ24770.1 - 9.3e-07 29.5 0.0 1.5e-06 28.8 0.0 1.3 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.15 CBZ24770.1 - 0.049 13.7 1.7 6.6 6.9 0.0 2.7 3 0 0 3 3 3 0 Complex 1 protein (LYR family) Serine_rich PF08824.10 CBZ24771.1 - 0.18 11.8 3.2 0.15 12.0 0.7 2.2 2 0 0 2 2 2 0 Serine rich protein interaction domain Peptidase_M16 PF00675.20 CBZ24775.1 - 2.6e-05 24.3 0.4 0.00054 20.0 0.0 2.7 2 1 0 2 2 2 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 CBZ24775.1 - 0.00063 19.8 0.0 0.0018 18.3 0.0 1.8 1 0 0 1 1 1 1 Peptidase M16 inactive domain Spt20 PF12090.8 CBZ24776.1 - 0.0055 16.3 19.0 0.0055 16.3 19.0 3.9 3 1 0 3 3 3 1 Spt20 family DUF3381 PF11861.8 CBZ24776.1 - 0.061 13.1 0.0 0.061 13.1 0.0 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF3381) LRR_6 PF13516.6 CBZ24779.1 - 6.5e-06 25.8 0.2 0.26 11.4 0.0 3.6 3 0 0 3 3 3 3 Leucine Rich repeat LRR_4 PF12799.7 CBZ24779.1 - 0.0056 17.1 2.9 0.012 16.1 1.4 2.2 1 1 1 2 2 2 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 CBZ24779.1 - 0.051 14.1 1.9 0.84 10.4 0.3 3.2 2 0 0 2 2 2 0 Leucine Rich Repeat LRR_8 PF13855.6 CBZ24779.1 - 0.23 11.3 1.8 0.76 9.6 0.8 2.3 1 1 1 2 2 2 0 Leucine rich repeat Ax_dynein_light PF10211.9 CBZ24780.1 - 0.0005 20.1 4.2 0.0005 20.1 4.2 2.2 2 0 0 2 2 2 1 Axonemal dynein light chain DUF4727 PF15856.5 CBZ24780.1 - 0.0024 17.5 0.1 1.4 8.5 0.0 2.6 2 0 0 2 2 2 2 Domain of unknown function (DUF4727) DUF4201 PF13870.6 CBZ24780.1 - 0.0077 16.0 4.2 0.019 14.7 4.2 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4201) Prominin PF05478.11 CBZ24780.1 - 0.18 9.7 2.4 0.28 9.1 2.4 1.2 1 0 0 1 1 1 0 Prominin Spc7 PF08317.11 CBZ24780.1 - 0.34 9.8 10.5 0.095 11.6 4.1 2.2 2 0 0 2 2 2 0 Spc7 kinetochore protein GvpG PF05120.12 CBZ24780.1 - 0.38 10.8 1.8 1.1 9.3 1.8 1.8 1 0 0 1 1 1 0 Gas vesicle protein G CENP-F_leu_zip PF10473.9 CBZ24780.1 - 0.66 10.0 12.8 0.49 10.4 4.1 2.5 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 TMF_TATA_bd PF12325.8 CBZ24780.1 - 1.7 8.9 12.9 0.091 13.0 4.8 2.6 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding AAA_13 PF13166.6 CBZ24780.1 - 4.5 5.8 6.0 1 7.9 2.6 1.5 2 0 0 2 2 2 0 AAA domain DUF4763 PF15960.5 CBZ24780.1 - 5 6.4 10.8 3.1 7.0 5.7 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4763) Atg14 PF10186.9 CBZ24780.1 - 6 5.9 9.9 0.41 9.7 3.8 2.0 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 Spc24 PF08286.11 CBZ24780.1 - 8.6 6.7 5.6 5.5 7.3 2.2 2.3 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 Glyco_transf_25 PF01755.17 CBZ24781.1 - 9.5e-19 68.0 0.0 1.5e-17 64.2 0.0 2.0 2 0 0 2 2 2 2 Glycosyltransferase family 25 (LPS biosynthesis protein) TRM PF02005.16 CBZ24782.1 - 4.4e-94 315.7 0.0 5.2e-45 154.2 0.0 3.1 3 0 0 3 3 3 3 N2,N2-dimethylguanosine tRNA methyltransferase DNA_pol_E_B PF04042.16 CBZ24782.1 - 0.13 11.6 0.0 0.46 9.8 0.0 1.8 2 0 0 2 2 2 0 DNA polymerase alpha/epsilon subunit B FYDLN_acid PF09538.10 CBZ24782.1 - 0.49 11.1 5.7 1.2 9.8 5.7 1.6 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) NPR3 PF03666.13 CBZ24782.1 - 4.9 5.8 7.5 7.1 5.3 7.5 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Actin PF00022.19 CBZ24783.1 - 6.1e-114 380.8 0.0 7e-113 377.3 0.0 2.3 1 1 0 1 1 1 1 Actin AAA PF00004.29 CBZ24784.1 - 4.8e-37 127.3 0.0 8.4e-37 126.6 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 CBZ24784.1 - 4.1e-08 32.9 0.2 9.8e-08 31.7 0.2 1.6 1 0 0 1 1 1 1 AAA+ lid domain LisH_TPL PF17814.1 CBZ24784.1 - 2.5e-06 27.0 0.7 5.7e-06 25.9 0.7 1.6 1 0 0 1 1 1 1 LisH-like dimerisation domain AAA_22 PF13401.6 CBZ24784.1 - 1.1e-05 25.8 3.0 0.027 14.7 0.1 3.4 2 1 1 3 3 3 2 AAA domain RuvB_N PF05496.12 CBZ24784.1 - 2e-05 24.4 0.0 3.5e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain Vps4_C PF09336.10 CBZ24784.1 - 0.00013 21.9 0.0 0.00036 20.5 0.0 1.7 1 0 0 1 1 1 1 Vps4 C terminal oligomerisation domain AAA_16 PF13191.6 CBZ24784.1 - 0.00038 20.9 0.0 0.0013 19.1 0.0 1.9 1 0 0 1 1 1 1 AAA ATPase domain AAA_24 PF13479.6 CBZ24784.1 - 0.0004 20.2 0.0 0.00073 19.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain TIP49 PF06068.13 CBZ24784.1 - 0.0011 18.3 0.0 0.0019 17.5 0.0 1.2 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_25 PF13481.6 CBZ24784.1 - 0.0015 18.1 0.2 0.12 11.9 0.2 2.5 1 1 1 2 2 2 1 AAA domain IstB_IS21 PF01695.17 CBZ24784.1 - 0.0046 16.7 0.0 0.01 15.6 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_18 PF13238.6 CBZ24784.1 - 0.0051 17.4 0.0 0.02 15.5 0.0 2.1 2 1 0 2 2 2 1 AAA domain AAA_5 PF07728.14 CBZ24784.1 - 0.008 16.2 0.1 0.021 14.8 0.1 1.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 CBZ24784.1 - 0.012 15.8 0.0 0.022 14.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) Mg_chelatase PF01078.21 CBZ24784.1 - 0.014 14.8 0.0 0.024 14.0 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_14 PF13173.6 CBZ24784.1 - 0.022 14.8 0.0 0.043 13.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 CBZ24784.1 - 0.023 14.2 0.0 0.054 13.0 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region ATPase PF06745.13 CBZ24784.1 - 0.029 13.7 0.1 0.72 9.2 0.1 2.2 1 1 1 2 2 2 0 KaiC LisH PF08513.11 CBZ24784.1 - 0.03 14.3 0.0 0.07 13.1 0.0 1.7 1 0 0 1 1 1 0 LisH RNA_helicase PF00910.22 CBZ24784.1 - 0.039 14.4 0.0 0.077 13.4 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_28 PF13521.6 CBZ24784.1 - 0.054 13.7 0.2 0.22 11.8 0.0 2.1 2 0 0 2 2 2 0 AAA domain PhoH PF02562.16 CBZ24784.1 - 0.064 12.7 0.1 0.16 11.4 0.0 1.6 2 0 0 2 2 2 0 PhoH-like protein AAA_33 PF13671.6 CBZ24784.1 - 0.073 13.2 0.0 0.16 12.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain Mesothelin PF06060.12 CBZ24784.1 - 0.14 10.3 0.0 0.23 9.6 0.0 1.2 1 0 0 1 1 1 0 Pre-pro-megakaryocyte potentiating factor precursor (Mesothelin) A_deaminase PF00962.22 CBZ24786.1 - 3.9e-86 289.4 0.0 5.3e-80 269.2 0.0 2.5 2 0 0 2 2 2 2 Adenosine/AMP deaminase ANTH PF07651.16 CBZ24787.1 - 1.1 8.3 4.0 2.3 7.1 0.6 2.3 2 0 0 2 2 2 0 ANTH domain CAP59_mtransfer PF11735.8 CBZ24790.1 - 4.8e-53 180.3 0.0 7.9e-52 176.3 0.0 2.2 2 0 0 2 2 2 1 Cryptococcal mannosyltransferase 1 Peptidase_S8 PF00082.22 CBZ24792.1 - 9.9e-25 87.4 0.0 6.9e-24 84.6 0.0 2.3 1 1 0 1 1 1 1 Subtilase family DUF5477 PF17571.2 CBZ24792.1 - 0.057 13.6 0.2 0.27 11.4 0.2 2.2 1 0 0 1 1 1 0 Family of unknown function (DUF5477) TPR_9 PF13371.6 CBZ24792.1 - 0.9 9.7 5.3 13 6.0 0.3 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat Dpy-30 PF05186.13 CBZ24793.1 - 4.4e-08 32.7 0.4 8e-08 31.8 0.4 1.5 1 0 0 1 1 1 1 Dpy-30 motif FeoB_Cyto PF17910.1 CBZ24793.1 - 0.2 12.2 0.0 0.39 11.3 0.0 1.4 1 0 0 1 1 1 0 FeoB cytosolic helical domain FAD_binding_6 PF00970.24 CBZ24794.1 - 1.1e-29 102.7 0.0 1.6e-29 102.2 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.21 CBZ24794.1 - 1.8e-28 99.3 0.0 1.1e-27 96.8 0.0 2.2 2 1 1 3 3 3 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.12 CBZ24794.1 - 0.0014 18.8 0.0 0.03 14.4 0.0 2.2 1 1 0 2 2 2 1 Ferric reductase NAD binding domain AAA PF00004.29 CBZ24797.1 - 1.6e-42 145.0 0.0 2.8e-42 144.3 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 CBZ24797.1 - 6.4e-09 35.5 0.5 1.3e-08 34.5 0.5 1.5 1 0 0 1 1 1 1 AAA+ lid domain Prot_ATP_ID_OB PF16450.5 CBZ24797.1 - 5.1e-07 29.6 0.1 1e-06 28.6 0.1 1.6 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_2 PF07724.14 CBZ24797.1 - 3.2e-06 27.3 0.0 6.4e-06 26.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 CBZ24797.1 - 5.5e-06 26.4 0.1 2e-05 24.6 0.1 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) Prot_ATP_OB_N PF17758.1 CBZ24797.1 - 2.3e-05 23.9 0.1 7.5e-05 22.3 0.0 1.9 2 0 0 2 2 1 1 Proteasomal ATPase OB N-terminal domain AAA_16 PF13191.6 CBZ24797.1 - 3.3e-05 24.3 0.2 0.0032 17.9 0.0 2.4 1 1 1 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 CBZ24797.1 - 4.6e-05 23.7 0.4 0.023 15.0 0.4 2.4 1 1 0 1 1 1 1 AAA domain DUF815 PF05673.13 CBZ24797.1 - 0.00048 19.4 0.0 0.00076 18.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) RuvB_N PF05496.12 CBZ24797.1 - 0.0014 18.4 0.0 0.0028 17.4 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_18 PF13238.6 CBZ24797.1 - 0.0029 18.2 0.0 0.0065 17.0 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 CBZ24797.1 - 0.0058 16.8 0.0 0.013 15.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_3 PF07726.11 CBZ24797.1 - 0.011 15.6 0.0 0.029 14.2 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ATPase PF06745.13 CBZ24797.1 - 0.025 13.9 0.2 0.31 10.4 0.1 2.2 1 1 1 2 2 2 0 KaiC RNA_helicase PF00910.22 CBZ24797.1 - 0.026 14.9 0.0 0.071 13.5 0.0 1.8 2 0 0 2 2 1 0 RNA helicase AAA_28 PF13521.6 CBZ24797.1 - 0.034 14.4 0.1 0.084 13.1 0.0 1.7 2 0 0 2 2 1 0 AAA domain AAA_14 PF13173.6 CBZ24797.1 - 0.035 14.1 0.0 0.07 13.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.6 CBZ24797.1 - 0.049 14.1 0.0 0.11 13.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 CBZ24797.1 - 0.052 13.3 0.0 0.11 12.2 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_24 PF13479.6 CBZ24797.1 - 0.06 13.1 0.5 0.25 11.0 0.2 2.3 2 1 0 2 2 2 0 AAA domain DUF2075 PF09848.9 CBZ24797.1 - 0.078 12.2 0.1 0.15 11.2 0.0 1.6 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) NACHT PF05729.12 CBZ24797.1 - 0.095 12.6 0.2 0.99 9.3 0.1 2.3 1 1 1 2 2 2 0 NACHT domain TIP49 PF06068.13 CBZ24797.1 - 0.1 11.8 0.0 0.19 10.9 0.0 1.3 1 0 0 1 1 1 0 TIP49 P-loop domain Mg_chelatase PF01078.21 CBZ24797.1 - 0.11 11.9 0.0 0.21 11.0 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI NB-ARC PF00931.22 CBZ24797.1 - 0.16 11.2 0.0 0.97 8.6 0.0 2.3 4 0 0 4 4 4 0 NB-ARC domain AAA_25 PF13481.6 CBZ24797.1 - 0.22 11.1 0.8 5.4 6.6 0.3 2.5 1 1 1 2 2 2 0 AAA domain tRNA-synt_1 PF00133.22 CBZ24798.1 - 2.6e-25 88.7 0.0 1.9e-13 49.6 0.0 4.1 3 1 0 3 3 3 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.11 CBZ24798.1 - 1.2e-19 70.4 0.0 4.2e-09 35.6 0.0 3.1 3 0 0 3 3 3 2 tRNA synthetases class I (M) Anticodon_1 PF08264.13 CBZ24798.1 - 2e-12 47.4 0.3 4.4e-12 46.2 0.3 1.6 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.19 CBZ24798.1 - 2.8e-07 30.2 0.0 1.4e-06 27.9 0.0 2.0 2 0 0 2 2 2 1 tRNA synthetases class I (C) catalytic domain RNA_pol_N PF01194.17 CBZ24800.1 - 1.5e-25 89.2 1.5 1.8e-25 89.0 1.5 1.1 1 0 0 1 1 1 1 RNA polymerases N / 8 kDa subunit DUF155 PF02582.14 CBZ24801.1 - 2.5e-39 135.2 0.0 3.6e-39 134.7 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 Abhydrolase_6 PF12697.7 CBZ24802.1 - 3.9e-15 57.0 4.4 4.5e-14 53.6 4.4 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 CBZ24802.1 - 1.5e-08 34.6 0.0 0.00069 19.3 0.0 2.4 2 0 0 2 2 2 2 alpha/beta hydrolase fold Esterase PF00756.20 CBZ24802.1 - 6.4e-05 22.7 0.0 0.00015 21.5 0.0 1.5 1 0 0 1 1 1 1 Putative esterase Hydrolase_4 PF12146.8 CBZ24802.1 - 0.00026 20.3 0.0 0.011 15.0 0.1 2.6 2 1 0 2 2 2 1 Serine aminopeptidase, S33 LIDHydrolase PF10230.9 CBZ24802.1 - 0.061 12.9 0.0 0.18 11.3 0.0 1.7 3 0 0 3 3 3 0 Lipid-droplet associated hydrolase DUF676 PF05057.14 CBZ24802.1 - 0.066 12.7 0.0 0.11 11.9 0.0 1.3 1 0 0 1 1 1 0 Putative serine esterase (DUF676) LCAT PF02450.15 CBZ24802.1 - 0.085 12.0 0.0 0.12 11.5 0.0 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase Abhydro_lipase PF04083.16 CBZ24802.1 - 0.1 12.2 0.0 0.29 10.8 0.0 1.7 2 0 0 2 2 2 0 Partial alpha/beta-hydrolase lipase region PGAP1 PF07819.13 CBZ24802.1 - 0.11 12.3 0.0 0.19 11.5 0.0 1.4 1 0 0 1 1 1 0 PGAP1-like protein Endonuc-BglII PF09195.11 CBZ24803.1 - 0.088 12.6 0.0 0.15 11.9 0.0 1.3 1 0 0 1 1 1 0 Restriction endonuclease BglII EF-hand_7 PF13499.6 CBZ24804.1 - 2.1e-15 56.9 0.8 3.2e-07 30.7 0.3 2.5 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_1 PF00036.32 CBZ24804.1 - 3.8e-13 48.0 5.9 1.2e-07 30.7 0.1 3.8 5 0 0 5 5 5 2 EF hand EF-hand_8 PF13833.6 CBZ24804.1 - 3.7e-11 42.7 1.5 0.0013 18.5 0.0 3.7 3 1 1 4 4 4 3 EF-hand domain pair EF-hand_6 PF13405.6 CBZ24804.1 - 2.7e-10 39.3 0.4 1.1e-05 25.0 0.1 3.9 2 1 1 3 3 3 2 EF-hand domain EF-hand_5 PF13202.6 CBZ24804.1 - 2.3e-06 26.8 0.2 3.7e-05 23.0 0.3 2.7 2 0 0 2 2 2 1 EF hand EF-hand_9 PF14658.6 CBZ24804.1 - 0.0017 18.7 0.0 0.52 10.7 0.0 2.3 2 0 0 2 2 2 1 EF-hand domain DUF4192 PF13830.6 CBZ24804.1 - 0.015 15.4 0.3 0.025 14.7 0.2 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4192) EF-hand_4 PF12763.7 CBZ24804.1 - 0.094 12.7 0.1 5.2 7.1 0.1 2.3 2 0 0 2 2 2 0 Cytoskeletal-regulatory complex EF hand PNRC PF15365.6 CBZ24804.1 - 0.12 12.2 5.4 0.3 10.9 5.4 1.7 1 0 0 1 1 1 0 Proline-rich nuclear receptor coactivator motif DUF1722 PF08349.11 CBZ24804.1 - 0.12 12.6 1.2 17 5.8 0.2 2.7 2 1 0 3 3 3 0 Protein of unknown function (DUF1722) DNA_ligase_IV PF11411.8 CBZ24804.1 - 0.7 10.1 2.2 5.7 7.2 0.1 2.9 3 0 0 3 3 3 0 DNA ligase IV MAM33 PF02330.16 CBZ24805.1 - 1.7e-09 38.0 0.1 4e-09 36.7 0.1 1.6 1 0 0 1 1 1 1 Mitochondrial glycoprotein Tctex-1 PF03645.13 CBZ24806.1 - 2.4e-23 82.3 0.0 2.8e-23 82.1 0.0 1.2 1 0 0 1 1 1 1 Tctex-1 family Rio2_N PF09202.11 CBZ24806.1 - 0.067 13.4 0.0 0.13 12.5 0.0 1.5 1 1 0 1 1 1 0 Rio2, N-terminal QueF PF14489.6 CBZ24806.1 - 0.089 13.0 0.0 0.2 11.8 0.0 1.5 2 0 0 2 2 2 0 QueF-like protein Adenylsucc_synt PF00709.21 CBZ24807.1 - 9.5e-93 311.4 0.0 1.2e-92 311.0 0.0 1.1 1 0 0 1 1 1 1 Adenylosuccinate synthetase Ribosomal_L27 PF01016.19 CBZ24808.1 - 0.13 12.3 0.3 0.25 11.4 0.3 1.5 1 1 0 1 1 1 0 Ribosomal L27 protein Nucleoside_tran PF01733.18 CBZ24809.1 - 7e-31 107.7 0.6 2.9e-19 69.6 0.0 2.3 2 0 0 2 2 2 2 Nucleoside transporter Ribosomal_S4e PF00900.20 CBZ24810.1 - 4.6e-24 84.1 0.1 8.3e-24 83.3 0.1 1.4 1 0 0 1 1 1 1 Ribosomal family S4e RS4NT PF08071.12 CBZ24810.1 - 1.1e-17 63.8 4.3 2.7e-17 62.6 4.3 1.6 1 0 0 1 1 1 1 RS4NT (NUC023) domain 40S_S4_C PF16121.5 CBZ24810.1 - 2.5e-16 59.0 0.0 4.9e-16 58.1 0.0 1.5 1 0 0 1 1 1 1 40S ribosomal protein S4 C-terminus S4 PF01479.25 CBZ24810.1 - 1.3e-06 28.0 0.0 2.6e-06 27.1 0.0 1.6 1 0 0 1 1 1 1 S4 domain KOW PF00467.29 CBZ24810.1 - 6.3e-05 22.8 0.3 0.00021 21.1 0.3 2.0 1 0 0 1 1 1 1 KOW motif Ribosomal_S4e PF00900.20 CBZ24811.1 - 2.1e-24 85.2 0.1 3.8e-24 84.4 0.1 1.4 1 0 0 1 1 1 1 Ribosomal family S4e RS4NT PF08071.12 CBZ24811.1 - 8.1e-18 64.2 4.7 1.9e-17 63.0 4.7 1.7 1 0 0 1 1 1 1 RS4NT (NUC023) domain 40S_S4_C PF16121.5 CBZ24811.1 - 1.4e-16 59.9 0.0 2.5e-16 59.0 0.0 1.4 1 0 0 1 1 1 1 40S ribosomal protein S4 C-terminus S4 PF01479.25 CBZ24811.1 - 6.1e-07 29.0 0.0 1.3e-06 28.0 0.0 1.6 1 0 0 1 1 1 1 S4 domain KOW PF00467.29 CBZ24811.1 - 0.0001 22.1 1.8 0.00011 22.0 0.3 1.9 2 0 0 2 2 2 1 KOW motif TPK_catalytic PF04263.16 CBZ24812.1 - 1.9e-09 37.6 0.0 0.0013 18.8 0.0 3.1 2 1 0 2 2 2 2 Thiamin pyrophosphokinase, catalytic domain TPK_B1_binding PF04265.14 CBZ24812.1 - 2.1e-06 27.4 0.0 1.1e-05 25.1 0.0 2.1 2 0 0 2 2 2 1 Thiamin pyrophosphokinase, vitamin B1 binding domain DUF5134 PF17197.4 CBZ24813.1 - 0.17 11.8 0.0 0.24 11.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5134) PRIMA1 PF16101.5 CBZ24814.1 - 0.011 15.8 0.0 0.16 12.0 0.0 2.0 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 DUF4381 PF14316.6 CBZ24814.1 - 0.017 15.4 0.2 0.033 14.4 0.0 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) TMEM132D_C PF15706.5 CBZ24814.1 - 0.068 13.0 0.0 0.14 12.0 0.0 1.5 1 0 0 1 1 1 0 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term SID-1_RNA_chan PF13965.6 CBZ24814.1 - 0.098 11.0 0.0 0.13 10.7 0.0 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 STE2 PF02116.15 CBZ24814.1 - 0.1 11.9 0.0 5.4 6.2 0.0 2.0 2 0 0 2 2 2 0 Fungal pheromone mating factor STE2 GPCR MENTAL PF10457.9 CBZ24814.1 - 0.1 12.4 0.0 0.13 12.0 0.0 1.2 1 0 0 1 1 1 0 Cholesterol-capturing domain EphA2_TM PF14575.6 CBZ24814.1 - 0.15 13.0 0.0 0.51 11.3 0.0 1.9 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain DUF4834 PF16118.5 CBZ24814.1 - 0.2 12.7 0.1 0.66 11.0 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) V_ATPase_I PF01496.19 CBZ24814.1 - 0.26 9.1 0.0 0.33 8.8 0.0 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family LapA_dom PF06305.11 CBZ24814.1 - 0.28 11.0 0.0 0.28 11.0 0.0 1.7 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain FAM176 PF14851.6 CBZ24814.1 - 1.6 8.4 4.5 3.1 7.5 4.5 1.5 1 1 0 1 1 1 0 FAM176 family Endonuclease_NS PF01223.23 CBZ24815.1 - 4.5e-18 65.9 0.0 9.6e-18 64.8 0.0 1.4 1 0 0 1 1 1 1 DNA/RNA non-specific endonuclease ATP_bind_1 PF03029.17 CBZ24816.1 - 1.9e-60 204.6 0.0 6.4e-58 196.4 0.0 2.0 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein SRP54 PF00448.22 CBZ24816.1 - 7.5e-06 25.7 0.0 0.00077 19.1 0.0 2.3 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain AAA_16 PF13191.6 CBZ24816.1 - 1.4e-05 25.6 0.1 3.7e-05 24.2 0.0 2.0 1 1 0 2 2 1 1 AAA ATPase domain GTP_EFTU PF00009.27 CBZ24816.1 - 2.8e-05 23.7 0.0 0.027 14.0 0.0 2.6 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 CBZ24816.1 - 9.3e-05 22.5 0.0 0.00018 21.5 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_24 PF13479.6 CBZ24816.1 - 0.0001 22.1 0.0 0.00018 21.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 CBZ24816.1 - 0.00021 21.2 0.0 2.2 8.1 0.0 3.5 4 0 0 4 4 4 2 RsgA GTPase MeaB PF03308.16 CBZ24816.1 - 0.00042 19.4 0.4 0.02 13.9 0.0 3.0 2 2 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB cobW PF02492.19 CBZ24816.1 - 0.0012 18.5 0.4 0.31 10.6 0.0 2.3 2 1 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_30 PF13604.6 CBZ24816.1 - 0.0013 18.5 0.1 0.003 17.3 0.1 1.7 1 1 0 1 1 1 1 AAA domain Arf PF00025.21 CBZ24816.1 - 0.0024 17.3 0.0 0.21 11.0 0.0 2.2 2 0 0 2 2 2 1 ADP-ribosylation factor family AAA_33 PF13671.6 CBZ24816.1 - 0.0025 18.0 0.0 0.0047 17.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 CBZ24816.1 - 0.0049 17.1 0.0 0.02 15.1 0.0 1.9 2 0 0 2 2 2 1 AAA domain NB-ARC PF00931.22 CBZ24816.1 - 0.0056 15.9 0.1 0.0094 15.2 0.1 1.3 1 0 0 1 1 1 1 NB-ARC domain Zeta_toxin PF06414.12 CBZ24816.1 - 0.0075 15.6 0.5 0.017 14.4 0.0 1.8 2 0 0 2 2 2 1 Zeta toxin NTPase_1 PF03266.15 CBZ24816.1 - 0.0098 15.8 0.1 0.047 13.6 0.1 2.0 1 1 0 1 1 1 1 NTPase AAA_19 PF13245.6 CBZ24816.1 - 0.011 16.0 0.4 0.023 15.0 0.4 1.6 1 1 0 1 1 1 0 AAA domain AAA_31 PF13614.6 CBZ24816.1 - 0.015 15.2 0.0 1.1 9.2 0.0 2.3 1 1 0 1 1 1 0 AAA domain AAA_7 PF12775.7 CBZ24816.1 - 0.017 14.7 0.0 0.028 13.9 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region NACHT PF05729.12 CBZ24816.1 - 0.017 15.0 0.0 0.049 13.5 0.0 1.8 1 0 0 1 1 1 0 NACHT domain 6PF2K PF01591.18 CBZ24816.1 - 0.023 14.0 0.0 0.037 13.3 0.0 1.2 1 0 0 1 1 1 0 6-phosphofructo-2-kinase DLIC PF05783.11 CBZ24816.1 - 0.023 13.5 0.2 0.16 10.8 0.0 1.9 2 0 0 2 2 2 0 Dynein light intermediate chain (DLIC) SRPRB PF09439.10 CBZ24816.1 - 0.025 14.0 0.0 1.2 8.5 0.0 2.2 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit G-alpha PF00503.20 CBZ24816.1 - 0.025 13.7 0.0 0.69 9.0 0.0 2.2 2 0 0 2 2 2 0 G-protein alpha subunit MobB PF03205.14 CBZ24816.1 - 0.033 14.1 0.0 0.079 12.9 0.0 1.6 2 0 0 2 2 1 0 Molybdopterin guanine dinucleotide synthesis protein B CLP1_P PF16575.5 CBZ24816.1 - 0.036 13.9 0.0 2.8 7.7 0.0 2.3 2 0 0 2 2 2 0 mRNA cleavage and polyadenylation factor CLP1 P-loop IstB_IS21 PF01695.17 CBZ24816.1 - 0.042 13.6 0.0 0.18 11.6 0.0 1.9 2 0 0 2 2 2 0 IstB-like ATP binding protein APS_kinase PF01583.20 CBZ24816.1 - 0.047 13.6 0.0 0.11 12.4 0.0 1.6 2 0 0 2 2 1 0 Adenylylsulphate kinase AAA_18 PF13238.6 CBZ24816.1 - 0.049 14.2 0.1 0.1 13.2 0.1 1.7 1 1 0 1 1 1 0 AAA domain Torsin PF06309.11 CBZ24816.1 - 0.05 13.7 0.0 0.086 13.0 0.0 1.3 1 0 0 1 1 1 0 Torsin Ras PF00071.22 CBZ24816.1 - 0.054 13.1 0.2 4.5 6.9 0.0 2.6 3 1 0 3 3 2 0 Ras family Roc PF08477.13 CBZ24816.1 - 0.059 13.6 0.1 0.48 10.6 0.0 2.2 2 1 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase CbiA PF01656.23 CBZ24816.1 - 0.066 13.3 0.0 0.085 12.9 0.0 1.4 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain ATPase_2 PF01637.18 CBZ24816.1 - 0.089 12.7 0.0 0.12 12.3 0.0 1.2 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA PF00004.29 CBZ24816.1 - 0.094 13.1 0.0 0.17 12.3 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Septin PF00735.18 CBZ24816.1 - 0.1 11.8 0.4 0.92 8.7 0.4 2.4 1 1 0 1 1 1 0 Septin MipZ PF09140.11 CBZ24816.1 - 0.11 11.8 0.0 0.19 11.0 0.0 1.4 1 1 0 1 1 1 0 ATPase MipZ Sigma54_activat PF00158.26 CBZ24816.1 - 0.12 12.0 0.0 0.28 10.9 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain KAP_NTPase PF07693.14 CBZ24816.1 - 0.13 11.5 0.0 0.14 11.3 0.0 1.3 1 0 0 1 1 1 0 KAP family P-loop domain PduV-EutP PF10662.9 CBZ24816.1 - 0.15 11.8 0.1 0.8 9.4 0.0 2.1 2 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_10 PF12846.7 CBZ24816.1 - 0.15 10.9 0.0 1.7 7.5 0.0 2.1 2 0 0 2 2 2 0 AAA-like domain AAA_5 PF07728.14 CBZ24816.1 - 0.16 11.9 0.0 0.3 11.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Complex1_LYR_1 PF13232.6 CBZ24818.1 - 1.3e-40 137.9 1.7 2.1e-40 137.2 1.7 1.3 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.15 CBZ24818.1 - 1.2e-05 25.2 0.1 3.7e-05 23.7 0.1 1.9 1 0 0 1 1 1 1 Complex 1 protein (LYR family) DUF4771 PF15995.5 CBZ24818.1 - 0.0028 17.9 0.4 0.0042 17.4 0.4 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4771) DUF5075 PF16825.5 CBZ24819.1 - 2e-09 37.4 0.4 5.1e-09 36.1 0.4 1.7 1 0 0 1 1 1 1 IGP family C-type lectin domain DUF3357 PF11837.8 CBZ24819.1 - 0.023 15.2 0.3 8.7 6.9 0.0 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF3357) Conotoxin PF02950.17 CBZ24819.1 - 0.3 12.1 0.3 0.3 12.1 0.3 1.8 2 0 0 2 2 2 0 Conotoxin DUF5075 PF16825.5 CBZ24820.1 - 1.5e-10 41.1 0.3 2.2e-10 40.5 0.3 1.3 1 0 0 1 1 1 1 IGP family C-type lectin domain Shisa PF13908.6 CBZ24820.1 - 0.003 17.8 0.1 0.0051 17.1 0.1 1.4 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator DUF4492 PF14899.6 CBZ24820.1 - 0.02 14.8 1.6 0.041 13.8 1.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4492) Ferlin_C PF16165.5 CBZ24820.1 - 0.022 14.7 0.0 0.036 14.0 0.0 1.2 1 0 0 1 1 1 0 Ferlin C-terminus DUF2561 PF10812.8 CBZ24820.1 - 0.04 14.0 0.0 0.069 13.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2561) TMEM52 PF14979.6 CBZ24820.1 - 0.057 13.3 1.8 0.1 12.5 1.8 1.3 1 0 0 1 1 1 0 Transmembrane 52 SUR7 PF06687.12 CBZ24820.1 - 0.062 12.9 0.5 0.11 12.2 0.5 1.3 1 0 0 1 1 1 0 SUR7/PalI family DUF5090 PF17009.5 CBZ24820.1 - 0.45 10.5 1.9 0.7 9.8 1.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5090) PRIMA1 PF16101.5 CBZ24820.1 - 1.3 9.0 5.2 3 7.9 5.2 1.5 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 TMIE PF16038.5 CBZ24820.1 - 3.1 7.7 6.5 5.3 7.0 6.5 1.3 1 0 0 1 1 1 0 TMIE protein DUF630 PF04783.12 CBZ24822.1 - 0.028 14.6 0.1 0.11 12.7 0.1 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF630) TMF_TATA_bd PF12325.8 CBZ24822.1 - 0.34 11.1 23.0 2.2 8.6 7.4 3.8 2 1 0 2 2 2 0 TATA element modulatory factor 1 TATA binding Phage_GP20 PF06810.11 CBZ24822.1 - 1.2 8.9 6.0 0.19 11.5 0.2 2.3 2 1 0 2 2 2 0 Phage minor structural protein GP20 NPV_P10 PF05531.12 CBZ24822.1 - 4.8 7.7 7.0 19 5.8 4.3 3.1 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Dpy-30 PF05186.13 CBZ24823.1 - 7.9e-13 47.9 0.6 1.8e-12 46.7 0.6 1.7 1 0 0 1 1 1 1 Dpy-30 motif Hydin_ADK PF17213.3 CBZ24823.1 - 0.00025 21.4 0.0 0.00025 21.4 0.0 2.6 3 0 0 3 3 3 1 Hydin Adenylate kinase-like domain AAA_18 PF13238.6 CBZ24823.1 - 0.032 14.8 0.0 19 5.8 0.0 3.0 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 CBZ24823.1 - 0.21 12.0 0.0 0.44 11.0 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 CBZ24823.1 - 3.4 8.0 9.9 0.56 10.6 0.2 3.4 4 0 0 4 4 4 0 AAA ATPase domain Ground-like PF04155.18 CBZ24824.1 - 0.065 13.9 0.0 0.38 11.4 0.0 2.3 1 1 1 2 2 2 0 Ground-like domain Sin_N PF04801.13 CBZ24825.1 - 3.4e-76 257.2 0.0 5.3e-76 256.5 0.0 1.3 1 0 0 1 1 1 1 Sin-like protein conserved region Botulinum_HA-17 PF05588.11 CBZ24825.1 - 0.24 11.5 0.0 12 6.0 0.0 2.3 2 0 0 2 2 2 0 Clostridium botulinum HA-17 domain EMP70 PF02990.16 CBZ24826.1 - 9.7e-108 361.1 21.3 1.7e-107 360.3 21.3 1.3 1 0 0 1 1 1 1 Endomembrane protein 70 Lactamase_B_2 PF12706.7 CBZ24827.1 - 1.3e-31 109.7 3.0 5e-19 68.6 0.1 2.2 2 0 0 2 2 2 2 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 CBZ24827.1 - 8.3e-13 48.5 0.0 1.2e-11 44.8 0.0 2.0 2 0 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 CBZ24827.1 - 0.003 17.6 0.0 0.091 12.8 0.0 2.2 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily WD40 PF00400.32 CBZ24828.1 - 0.09 13.7 1.8 44 5.2 0.0 4.4 4 0 0 4 4 4 0 WD domain, G-beta repeat LRR_4 PF12799.7 CBZ24831.1 - 8.5e-11 41.9 14.5 3.6e-06 27.2 0.7 3.3 1 1 2 3 3 3 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CBZ24831.1 - 2.1e-05 24.2 7.2 0.00023 20.9 2.4 2.5 2 0 0 2 2 2 2 Leucine rich repeat zn-ribbon_14 PF16503.5 CBZ24831.1 - 0.03 13.8 0.1 0.067 12.7 0.1 1.6 1 0 0 1 1 1 0 Zinc-ribbon LRR_9 PF14580.6 CBZ24831.1 - 0.061 12.8 0.5 0.22 11.0 0.1 1.9 2 0 0 2 2 2 0 Leucine-rich repeat DUF4698 PF15769.5 CBZ24831.1 - 0.092 11.8 3.1 0.15 11.1 3.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4698) LRR_1 PF00560.33 CBZ24831.1 - 0.2 12.3 2.1 4.3 8.3 0.0 3.5 4 0 0 4 4 4 0 Leucine Rich Repeat LRR_6 PF13516.6 CBZ24831.1 - 0.53 10.5 6.5 6.8 7.0 0.1 3.3 4 0 0 4 4 4 0 Leucine Rich repeat Hamartin PF04388.12 CBZ24831.1 - 0.55 8.8 9.1 0.73 8.4 9.1 1.2 1 0 0 1 1 1 0 Hamartin protein EF-hand_7 PF13499.6 CBZ24833.1 - 6.6e-20 71.3 3.5 4.3e-08 33.5 0.2 3.3 3 1 0 3 3 3 3 EF-hand domain pair EF-hand_1 PF00036.32 CBZ24833.1 - 2.1e-18 64.4 0.5 0.0038 16.7 0.0 5.5 5 1 0 5 5 5 5 EF hand EF-hand_6 PF13405.6 CBZ24833.1 - 2.4e-17 61.3 4.5 0.00064 19.5 0.0 5.3 4 1 1 5 5 5 4 EF-hand domain EF-hand_5 PF13202.6 CBZ24833.1 - 4.5e-15 54.4 1.1 0.0022 17.4 0.0 4.9 5 0 0 5 5 5 4 EF hand EF-hand_8 PF13833.6 CBZ24833.1 - 2e-11 43.5 2.2 0.0023 17.7 0.0 4.9 3 2 2 5 5 5 3 EF-hand domain pair EF-hand_9 PF14658.6 CBZ24833.1 - 0.013 15.8 0.6 1.1 9.7 0.0 3.4 3 2 0 3 3 3 0 EF-hand domain Caleosin PF05042.13 CBZ24833.1 - 0.061 13.3 2.3 17 5.3 0.5 3.8 1 1 1 2 2 2 0 Caleosin related protein EF-hand_1 PF00036.32 CBZ24834.1 - 4.1e-22 76.0 0.1 0.00018 20.8 0.0 5.2 5 0 0 5 5 5 5 EF hand EF-hand_6 PF13405.6 CBZ24834.1 - 1.8e-20 71.0 0.3 0.0002 21.0 0.0 5.2 5 0 0 5 5 5 4 EF-hand domain EF-hand_7 PF13499.6 CBZ24834.1 - 2.5e-20 72.7 0.2 8.8e-09 35.7 0.0 3.1 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_8 PF13833.6 CBZ24834.1 - 1.2e-15 57.0 0.1 5.7e-07 29.3 0.0 4.2 3 2 2 5 5 5 3 EF-hand domain pair EF-hand_5 PF13202.6 CBZ24834.1 - 1.5e-14 52.7 0.4 9.6e-06 24.9 0.0 3.9 4 0 0 4 4 4 3 EF hand EF-hand_9 PF14658.6 CBZ24834.1 - 0.0047 17.2 0.1 7.6 7.0 0.0 3.3 3 0 0 3 3 3 1 EF-hand domain DUF5580 PF17743.1 CBZ24834.1 - 0.02 13.4 0.0 2.3 6.7 0.0 2.0 1 1 1 2 2 2 0 Family of unknown function (DUF5580) Phage_T4_Ndd PF06591.11 CBZ24834.1 - 0.034 13.9 0.2 0.047 13.5 0.2 1.3 1 0 0 1 1 1 0 T4-like phage nuclear disruption protein (Ndd) Caleosin PF05042.13 CBZ24834.1 - 0.073 13.0 2.0 53 3.7 0.0 3.8 2 2 2 4 4 4 0 Caleosin related protein TerB PF05099.13 CBZ24834.1 - 0.14 12.1 0.0 0.24 11.3 0.0 1.4 1 0 0 1 1 1 0 Tellurite resistance protein TerB HECT PF00632.25 CBZ24835.1 - 5.1e-45 154.3 0.0 1.1e-44 153.2 0.0 1.5 1 1 0 1 1 1 1 HECT-domain (ubiquitin-transferase) SPRY PF00622.28 CBZ24835.1 - 2.7e-24 85.6 0.2 4.8e-10 39.6 0.0 3.9 3 0 0 3 3 3 3 SPRY domain Ran_BP1 PF00638.18 CBZ24836.1 - 6.2e-26 91.1 1.3 8.3e-26 90.7 1.3 1.1 1 0 0 1 1 1 1 RanBP1 domain WH1 PF00568.23 CBZ24836.1 - 0.036 14.0 0.0 0.05 13.6 0.0 1.3 1 0 0 1 1 1 0 WH1 domain FlhE PF06366.13 CBZ24836.1 - 0.16 12.0 0.1 0.34 10.9 0.0 1.6 2 0 0 2 2 2 0 Flagellar protein FlhE DRMBL PF07522.14 CBZ24837.1 - 0.061 13.5 0.0 0.18 12.0 0.0 1.8 1 0 0 1 1 1 0 DNA repair metallo-beta-lactamase Cnd2 PF05786.14 CBZ24837.1 - 0.075 11.7 0.0 0.11 11.1 0.0 1.2 1 0 0 1 1 1 0 Condensin complex subunit 2 SUIM_assoc PF16619.5 CBZ24837.1 - 2.4 8.3 5.3 4.3 7.5 0.3 2.9 3 0 0 3 3 3 0 Unstructured region C-term to UIM in Ataxin3 PIN_4 PF13638.6 CBZ24838.1 - 9.1e-18 64.8 0.0 1.6e-17 64.0 0.0 1.3 1 0 0 1 1 1 1 PIN domain Metallophos PF00149.28 CBZ24839.1 - 2.2e-25 90.4 0.0 3.6e-25 89.7 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 CBZ24839.1 - 0.00041 20.7 0.0 0.00094 19.6 0.0 1.7 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain AAA PF00004.29 CBZ24840.1 - 5.8e-18 65.6 0.0 1.5e-17 64.3 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 CBZ24840.1 - 0.0042 16.8 0.0 0.011 15.5 0.0 1.7 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_25 PF13481.6 CBZ24840.1 - 0.02 14.5 0.8 0.086 12.4 0.1 2.3 2 1 1 3 3 3 0 AAA domain AAA_16 PF13191.6 CBZ24840.1 - 0.033 14.6 0.0 0.033 14.6 0.0 3.8 3 2 0 3 3 3 0 AAA ATPase domain AAA_22 PF13401.6 CBZ24840.1 - 0.048 13.9 0.0 0.18 12.1 0.0 2.0 1 0 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.18 CBZ24840.1 - 0.05 13.0 1.3 0.14 11.5 0.0 2.4 3 0 0 3 3 3 0 FtsK/SpoIIIE family RNA_helicase PF00910.22 CBZ24840.1 - 0.11 12.9 0.0 0.66 10.4 0.0 2.3 2 0 0 2 2 2 0 RNA helicase AAA_5 PF07728.14 CBZ24840.1 - 0.11 12.5 0.0 0.41 10.6 0.0 2.0 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) PhoLip_ATPase_C PF16212.5 CBZ24841.1 - 9.3e-65 218.8 21.4 9.3e-65 218.8 21.4 2.2 2 0 0 2 2 2 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 CBZ24841.1 - 2.3e-22 78.4 4.5 2.3e-22 78.4 4.5 2.5 2 0 0 2 2 2 1 Phospholipid-translocating ATPase N-terminal Cation_ATPase PF13246.6 CBZ24841.1 - 4.5e-10 39.5 0.0 5.7e-09 35.9 0.0 2.3 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 CBZ24841.1 - 5.1e-10 40.0 0.0 3.5e-05 24.2 0.0 2.9 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 CBZ24841.1 - 1.4e-08 34.5 0.3 1.4e-08 34.5 0.3 3.4 3 1 0 3 3 3 1 E1-E2 ATPase Hydrolase_3 PF08282.12 CBZ24841.1 - 0.12 12.0 0.0 0.25 11.0 0.0 1.4 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase NIF PF03031.18 CBZ24842.1 - 0.0097 15.7 0.0 1.1 9.0 0.0 2.3 2 0 0 2 2 2 2 NLI interacting factor-like phosphatase PMC2NT PF08066.12 CBZ24842.1 - 0.14 12.9 0.0 0.34 11.6 0.0 1.6 1 0 0 1 1 1 0 PMC2NT (NUC016) domain Gtr1_RagA PF04670.12 CBZ24844.1 - 2.4e-90 301.9 0.0 3.2e-90 301.5 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Roc PF08477.13 CBZ24844.1 - 2.3e-06 27.8 0.0 1.6e-05 25.1 0.0 2.1 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 CBZ24844.1 - 5.6e-05 22.8 0.0 0.00014 21.5 0.0 1.6 2 0 0 2 2 2 1 Ras family Arf PF00025.21 CBZ24844.1 - 0.00017 21.1 0.0 0.001 18.5 0.0 2.0 2 0 0 2 2 2 1 ADP-ribosylation factor family RuvB_N PF05496.12 CBZ24844.1 - 0.076 12.8 0.0 0.15 11.8 0.0 1.5 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain ABC_tran PF00005.27 CBZ24844.1 - 0.13 12.8 0.0 0.26 11.8 0.0 1.5 1 0 0 1 1 1 0 ABC transporter Metallophos PF00149.28 CBZ24845.1 - 4.7e-25 89.3 0.0 7.3e-25 88.7 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 CBZ24845.1 - 0.00075 19.9 0.0 0.0014 19.0 0.0 1.5 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain UQ_con PF00179.26 CBZ24846.1 - 9.1e-15 54.5 0.0 9.7e-15 54.4 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 CBZ24846.1 - 0.0038 17.5 0.0 0.0039 17.5 0.0 1.2 1 0 0 1 1 1 1 RWD domain LD_cluster2 PF18163.1 CBZ24846.1 - 0.086 12.3 0.0 0.11 11.9 0.0 1.1 1 0 0 1 1 1 0 SLOG cluster2 Tcp10_C PF07202.13 CBZ24847.1 - 2e-27 96.3 0.4 4.8e-27 95.0 0.0 1.9 2 0 0 2 2 2 1 T-complex protein 10 C-terminus MORN_2 PF07661.13 CBZ24847.1 - 0.13 12.6 0.0 11 6.6 0.0 3.1 2 0 0 2 2 2 0 MORN repeat variant Seadorna_VP6 PF07407.11 CBZ24847.1 - 0.23 10.4 0.4 0.35 9.8 0.4 1.2 1 0 0 1 1 1 0 Seadornavirus VP6 protein Glyco_trans_1_2 PF13524.6 CBZ24848.1 - 0.63 10.5 5.2 14 6.2 0.2 3.6 2 1 0 2 2 2 0 Glycosyl transferases group 1 Kinesin PF00225.23 CBZ24849.1 - 2.4e-92 309.4 0.0 3.3e-92 309.0 0.0 1.2 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 CBZ24849.1 - 2.8e-16 59.8 0.0 5.6e-16 58.8 0.0 1.5 1 0 0 1 1 1 1 Microtubule binding SAM_1 PF00536.30 CBZ24849.1 - 0.00056 20.3 0.2 0.00056 20.3 0.2 2.2 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 CBZ24849.1 - 0.046 13.8 0.2 0.1 12.7 0.2 1.6 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) BLOC1_2 PF10046.9 CBZ24849.1 - 0.054 13.8 0.1 0.14 12.5 0.1 1.6 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 SE PF08491.10 CBZ24850.1 - 7.5e-61 205.6 0.0 1.1e-60 205.1 0.0 1.2 1 0 0 1 1 1 1 Squalene epoxidase FAD_binding_3 PF01494.19 CBZ24850.1 - 1.5e-08 34.3 0.0 4.2e-08 32.8 0.0 1.7 1 1 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.12 CBZ24850.1 - 0.0017 17.5 0.0 1.5 7.8 0.1 2.3 2 0 0 2 2 2 2 Lycopene cyclase protein Pyr_redox_2 PF07992.14 CBZ24850.1 - 0.003 16.8 0.1 0.0078 15.5 0.1 1.6 1 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 CBZ24850.1 - 0.017 15.3 0.0 0.06 13.6 0.0 1.9 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.7 CBZ24850.1 - 0.018 14.4 0.1 0.027 13.8 0.1 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase GDI PF00996.18 CBZ24850.1 - 0.049 12.2 0.0 0.073 11.6 0.0 1.2 1 0 0 1 1 1 0 GDP dissociation inhibitor FAD_binding_2 PF00890.24 CBZ24850.1 - 0.11 11.5 0.1 0.18 10.9 0.1 1.3 1 0 0 1 1 1 0 FAD binding domain DNA_pol_A PF00476.20 CBZ24851.1 - 5e-37 127.9 0.2 1.4e-36 126.4 0.0 1.8 2 0 0 2 2 2 1 DNA polymerase family A DNA_pol_A_exo1 PF01612.20 CBZ24851.1 - 0.00046 19.9 0.0 0.0012 18.5 0.0 1.7 1 0 0 1 1 1 1 3'-5' exonuclease DUF5076 PF16826.5 CBZ24851.1 - 0.16 12.0 0.0 0.5 10.3 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF5076) Pkinase PF00069.25 CBZ24852.1 - 2.3e-51 174.7 0.0 2e-48 165.1 0.0 3.4 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ24852.1 - 7.8e-21 74.5 0.0 3.9e-17 62.4 0.0 2.5 3 0 0 3 3 3 2 Protein tyrosine kinase Haspin_kinase PF12330.8 CBZ24852.1 - 7.6e-05 21.8 0.0 0.00011 21.2 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 CBZ24852.1 - 0.0024 17.2 0.0 0.0059 16.0 0.0 1.6 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 CBZ24852.1 - 0.0033 17.4 0.0 0.013 15.4 0.0 2.1 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 CBZ24852.1 - 0.093 12.1 0.0 0.17 11.2 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 CBZ24852.1 - 0.11 12.1 0.1 0.19 11.3 0.1 1.3 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 AAA_6 PF12774.7 CBZ24853.1 - 3.1e-142 473.4 0.0 7.2e-141 468.9 0.0 2.8 2 0 0 2 2 2 1 Hydrolytic ATP binding site of dynein motor region DHC_N1 PF08385.12 CBZ24853.1 - 9.1e-134 447.2 1.7 7.7e-133 444.1 0.1 2.9 2 0 0 2 2 2 1 Dynein heavy chain, N-terminal region 1 DHC_N2 PF08393.13 CBZ24853.1 - 1.8e-110 369.8 1.5 1.8e-110 369.8 1.5 3.2 2 0 0 2 2 2 1 Dynein heavy chain, N-terminal region 2 AAA_8 PF12780.7 CBZ24853.1 - 1.4e-93 313.0 0.2 5.6e-93 311.0 0.0 2.3 2 0 0 2 2 2 1 P-loop containing dynein motor region D4 MT PF12777.7 CBZ24853.1 - 5.8e-86 288.6 11.2 5.8e-86 288.6 11.2 1.8 2 0 0 2 2 2 1 Microtubule-binding stalk of dynein motor AAA_9 PF12781.7 CBZ24853.1 - 4.3e-83 277.8 0.1 4.3e-83 277.8 0.1 3.4 3 0 0 3 3 3 1 ATP-binding dynein motor region Dynein_C PF18199.1 CBZ24853.1 - 5.1e-77 259.1 0.2 1.8e-76 257.3 0.2 2.1 1 0 0 1 1 1 1 Dynein heavy chain C-terminal domain AAA_7 PF12775.7 CBZ24853.1 - 1e-67 227.2 0.9 6.5e-63 211.5 0.2 3.8 3 0 0 3 3 3 2 P-loop containing dynein motor region AAA_lid_11 PF18198.1 CBZ24853.1 - 3.2e-46 157.2 0.0 9e-46 155.7 0.0 1.9 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain Dynein_heavy PF03028.15 CBZ24853.1 - 6.4e-35 119.8 0.0 1.4e-21 76.8 0.0 4.7 4 0 0 4 4 4 2 Dynein heavy chain region D6 P-loop domain AAA_lid_1 PF17857.1 CBZ24853.1 - 1.3e-26 92.7 0.2 6.8e-26 90.4 0.2 2.3 1 0 0 1 1 1 1 AAA+ lid domain Dynein_AAA_lid PF17852.1 CBZ24853.1 - 3.3e-24 85.4 0.3 1.3e-23 83.5 0.3 2.2 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain AAA_5 PF07728.14 CBZ24853.1 - 1.8e-21 76.6 0.0 1.7e-07 31.3 0.0 5.7 5 0 0 5 5 5 3 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 CBZ24853.1 - 1.2e-07 32.4 0.5 0.04 14.5 0.0 6.3 5 0 0 5 5 5 1 AAA domain AAA PF00004.29 CBZ24853.1 - 2.5e-06 28.0 0.0 0.18 12.2 0.0 3.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 CBZ24853.1 - 3.7e-05 24.0 0.9 3.9 7.7 0.0 5.4 6 0 0 6 6 4 1 AAA domain AAA_16 PF13191.6 CBZ24853.1 - 7.3e-05 23.2 7.4 0.43 11.0 0.0 6.1 6 1 0 6 6 4 1 AAA ATPase domain AAA_19 PF13245.6 CBZ24853.1 - 0.00022 21.6 0.8 0.53 10.6 0.0 3.8 3 0 0 3 3 3 1 AAA domain Mg_chelatase PF01078.21 CBZ24853.1 - 0.0042 16.5 0.2 0.71 9.2 0.0 3.9 4 0 0 4 4 4 1 Magnesium chelatase, subunit ChlI TsaE PF02367.17 CBZ24853.1 - 0.037 14.0 0.5 24 4.9 0.0 3.9 3 0 0 3 3 3 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE DUF815 PF05673.13 CBZ24853.1 - 0.046 12.9 0.0 0.68 9.0 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF815) ABC_tran PF00005.27 CBZ24853.1 - 0.058 13.9 0.1 53 4.3 0.0 4.1 3 0 0 3 3 3 0 ABC transporter AAA_28 PF13521.6 CBZ24853.1 - 0.074 13.3 1.2 27 5.0 0.1 3.9 3 0 0 3 3 3 0 AAA domain RNA_helicase PF00910.22 CBZ24853.1 - 0.095 13.1 0.5 69 3.9 0.0 4.4 4 0 0 4 4 4 0 RNA helicase IstB_IS21 PF01695.17 CBZ24853.1 - 0.1 12.3 0.1 0.95 9.2 0.0 2.7 3 0 0 3 3 3 0 IstB-like ATP binding protein AAA_33 PF13671.6 CBZ24853.1 - 0.24 11.6 0.8 27 4.9 0.0 3.8 4 0 0 4 4 4 0 AAA domain Allexi_40kDa PF05549.11 CBZ24853.1 - 7.4 6.0 8.1 23 4.4 0.0 4.1 4 0 0 4 4 4 0 Allexivirus 40kDa protein Cpn60_TCP1 PF00118.24 CBZ24854.1 - 1.5e-162 541.7 6.5 1.7e-162 541.5 6.5 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family FeoB_Cyto PF17910.1 CBZ24854.1 - 0.037 14.6 0.5 6.8 7.3 0.1 3.1 3 0 0 3 3 3 0 FeoB cytosolic helical domain Ribosomal_L44 PF00935.19 CBZ24855.1 - 1.2e-31 109.0 9.1 1.7e-31 108.5 9.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L44 P5CR_dimer PF14748.6 CBZ24856.1 - 1.8e-36 124.5 1.5 3e-36 123.8 1.5 1.4 1 0 0 1 1 1 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.17 CBZ24856.1 - 4.8e-16 59.1 0.0 1e-15 58.1 0.0 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.15 CBZ24856.1 - 1e-05 25.8 0.0 2e-05 24.8 0.0 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase ApbA PF02558.16 CBZ24856.1 - 0.00091 18.9 0.2 0.0023 17.6 0.2 1.7 1 1 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Shikimate_DH PF01488.20 CBZ24856.1 - 0.0086 16.1 0.0 0.016 15.3 0.0 1.6 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase 2-Hacid_dh_C PF02826.19 CBZ24856.1 - 0.038 13.4 0.0 0.058 12.7 0.0 1.2 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IlvN PF07991.12 CBZ24856.1 - 0.041 13.4 0.1 0.057 13.0 0.1 1.2 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain CbiC PF02570.15 CBZ24856.1 - 0.043 13.5 0.3 0.16 11.6 0.2 1.9 2 0 0 2 2 2 0 Precorrin-8X methylmutase PDH PF02153.17 CBZ24856.1 - 0.11 11.5 0.1 0.17 10.9 0.1 1.2 1 0 0 1 1 1 0 Prephenate dehydrogenase MFS_1 PF07690.16 CBZ24857.1 - 4.1e-17 62.1 35.2 1.2e-14 54.0 27.0 2.2 2 0 0 2 2 2 2 Major Facilitator Superfamily Nodulin-like PF06813.13 CBZ24857.1 - 9.7e-12 44.9 14.8 9.7e-12 44.9 14.8 2.6 2 1 0 2 2 2 1 Nodulin-like TssO PF17561.2 CBZ24857.1 - 0.0023 18.0 0.2 0.0023 18.0 0.2 2.5 2 0 0 2 2 2 1 Type VI secretion system, TssO HbrB PF08539.11 CBZ24857.1 - 0.06 13.3 0.0 0.1 12.6 0.0 1.3 1 0 0 1 1 1 0 HbrB-like E1-E2_ATPase PF00122.20 CBZ24857.1 - 0.13 11.8 2.5 7.4 6.1 0.1 2.7 2 0 0 2 2 2 0 E1-E2 ATPase LRR_4 PF12799.7 CBZ24858.1 - 3.8e-16 58.9 0.0 0.0055 17.1 0.0 6.2 5 1 1 6 6 6 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CBZ24858.1 - 0.0083 15.9 0.2 0.79 9.5 0.0 4.1 5 0 0 5 5 5 1 Leucine rich repeat KH_6 PF15985.5 CBZ24859.1 - 5.1e-12 45.9 0.0 1.2e-11 44.8 0.0 1.7 1 0 0 1 1 1 1 KH domain PI3Ka PF00613.20 CBZ24860.1 - 2.6e-46 157.4 2.0 4.8e-46 156.5 2.0 1.3 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3_PI4_kinase PF00454.27 CBZ24860.1 - 1.3e-45 156.2 0.0 4.3e-45 154.5 0.0 1.8 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3K_C2 PF00792.24 CBZ24860.1 - 2.1e-09 37.4 0.0 4.8e-09 36.3 0.0 1.5 1 0 0 1 1 1 1 Phosphoinositide 3-kinase C2 PI3K_rbd PF00794.18 CBZ24860.1 - 2.2e-09 37.4 0.0 1.7e-08 34.6 0.0 2.4 3 0 0 3 3 3 1 PI3-kinase family, ras-binding domain SNF2_N PF00176.23 CBZ24862.1 - 1.1e-20 73.6 0.0 2.6e-20 72.4 0.0 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain Tet_JBP PF12851.7 CBZ24862.1 - 2.9e-20 72.9 0.1 1.1e-16 61.1 0.0 2.3 1 1 1 2 2 2 2 Oxygenase domain of the 2OGFeDO superfamily Helicase_C PF00271.31 CBZ24862.1 - 1.9e-14 53.9 0.2 3.9e-14 52.9 0.2 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 CBZ24862.1 - 3.4e-09 37.0 0.0 1e-08 35.4 0.0 1.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 CBZ24862.1 - 0.0011 18.2 0.5 0.0019 17.5 0.5 1.3 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase DUF2095 PF09868.9 CBZ24862.1 - 0.02 14.9 0.0 0.051 13.5 0.0 1.6 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2095) DEAD PF00270.29 CBZ24862.1 - 0.033 14.0 0.0 0.091 12.5 0.0 1.8 1 1 0 1 1 1 0 DEAD/DEAH box helicase cNMP_binding PF00027.29 CBZ24863.1 - 0.00041 20.4 0.2 22 5.2 0.0 4.5 4 1 0 4 4 4 3 Cyclic nucleotide-binding domain Arf PF00025.21 CBZ24864.1 - 6.3e-05 22.5 0.0 0.00015 21.3 0.0 1.6 1 1 0 1 1 1 1 ADP-ribosylation factor family AAA_28 PF13521.6 CBZ24864.1 - 0.026 14.8 0.2 0.041 14.1 0.2 1.4 1 0 0 1 1 1 0 AAA domain DHHC PF01529.20 CBZ24865.1 - 2.5e-24 85.9 12.7 2.5e-24 85.9 12.7 2.1 2 0 0 2 2 2 1 DHHC palmitoyltransferase COX8 PF02285.15 CBZ24865.1 - 2.9 7.8 6.5 0.2 11.6 0.5 2.2 2 0 0 2 2 2 0 Cytochrome oxidase c subunit VIII Yip1 PF04893.17 CBZ24865.1 - 6.9 6.4 17.7 0.86 9.3 4.7 2.8 2 1 1 3 3 3 0 Yip1 domain PRP1_N PF06424.12 CBZ24866.1 - 0.047 14.1 0.1 0.047 14.1 0.1 1.8 2 0 0 2 2 2 0 PRP1 splicing factor, N-terminal DnaJ PF00226.31 CBZ24867.1 - 2.1e-05 24.6 0.0 4.9e-05 23.4 0.0 1.6 1 0 0 1 1 1 1 DnaJ domain YecM PF06185.12 CBZ24867.1 - 0.087 12.5 0.3 0.31 10.7 0.0 1.9 2 0 0 2 2 2 0 YecM protein CH PF00307.31 CBZ24868.1 - 0.015 15.5 0.0 0.069 13.3 0.0 2.1 2 0 0 2 2 2 0 Calponin homology (CH) domain CAP-ZIP_m PF15255.6 CBZ24868.1 - 0.12 12.6 1.2 0.33 11.2 1.2 1.7 1 0 0 1 1 1 0 WASH complex subunit CAP-Z interacting, central region GrpE PF01025.19 CBZ24868.1 - 0.84 9.3 9.2 0.25 11.0 5.4 2.1 2 0 0 2 2 2 0 GrpE Phage_GP20 PF06810.11 CBZ24868.1 - 1.9 8.3 9.7 0.22 11.3 4.3 2.1 2 0 0 2 2 2 0 Phage minor structural protein GP20 BORCS8 PF10167.9 CBZ24868.1 - 3.9 7.5 7.0 0.89 9.5 1.5 2.6 3 0 0 3 3 3 0 BLOC-1-related complex sub-unit 8 DivIC PF04977.15 CBZ24868.1 - 4.9 7.0 9.4 1.9 8.3 5.6 2.4 2 0 0 2 2 2 0 Septum formation initiator DnaJ PF00226.31 CBZ24869.1 - 5.7e-13 48.8 0.4 1e-12 48.0 0.4 1.5 1 0 0 1 1 1 1 DnaJ domain IU_nuc_hydro PF01156.19 CBZ24871.1 - 1.1e-69 235.4 0.1 1.3e-69 235.1 0.1 1.0 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase MOZ_SAS PF01853.18 CBZ24872.1 - 1.9e-63 213.4 0.0 2.9e-63 212.8 0.0 1.3 1 0 0 1 1 1 1 MOZ/SAS family zf-MYST PF17772.1 CBZ24872.1 - 9.6e-09 34.7 0.3 5e-05 22.8 0.0 2.5 2 0 0 2 2 2 2 MYST family zinc finger domain Tudor-knot PF11717.8 CBZ24872.1 - 1.8e-08 34.1 0.0 4.7e-08 32.8 0.0 1.7 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Acetyltransf_7 PF13508.7 CBZ24872.1 - 0.00076 19.9 0.0 0.0027 18.1 0.0 1.9 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 CBZ24872.1 - 0.031 14.5 0.0 0.086 13.1 0.0 1.8 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family zf-C2H2_4 PF13894.6 CBZ24872.1 - 0.081 13.8 0.1 0.33 11.9 0.1 2.2 1 0 0 1 1 1 0 C2H2-type zinc finger zf-Di19 PF05605.12 CBZ24872.1 - 0.67 10.3 5.2 5 7.5 0.8 2.5 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding Ribosomal_L12 PF00542.19 CBZ24873.1 - 3.8e-17 62.4 2.6 7.6e-17 61.4 2.6 1.5 1 0 0 1 1 1 1 Ribosomal protein L7/L12 C-terminal domain Ribosomal_60s PF00428.19 CBZ24873.1 - 1.3 9.6 12.1 0.31 11.6 7.7 2.1 1 1 1 2 2 2 0 60s Acidic ribosomal protein Chromo PF00385.24 CBZ24874.1 - 0.0034 17.2 0.2 0.0034 17.2 0.2 1.8 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain Mersacidin PF16934.5 CBZ24875.1 - 0.007 16.1 0.2 0.88 9.4 0.0 3.3 3 0 0 3 3 3 2 Two-component Enterococcus faecalis cytolysin (EFC) Thioredoxin_8 PF13905.6 CBZ24877.1 - 2.9e-08 33.9 0.1 4.6e-08 33.3 0.1 1.2 1 0 0 1 1 1 1 Thioredoxin-like AhpC-TSA PF00578.21 CBZ24877.1 - 0.00017 21.5 0.1 0.00023 21.1 0.1 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 CBZ24877.1 - 0.00049 19.8 0.1 0.00059 19.6 0.1 1.1 1 0 0 1 1 1 1 Redoxin BBIP10 PF14777.6 CBZ24878.1 - 3.1e-24 84.3 0.7 4.9e-24 83.7 0.7 1.3 1 0 0 1 1 1 1 Cilia BBSome complex subunit 10 DUF4201 PF13870.6 CBZ24879.1 - 5.8e-30 104.3 9.0 5.8e-30 104.3 9.0 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF4201) Phyto-Amp PF15438.6 CBZ24879.1 - 0.13 12.1 0.0 0.22 11.3 0.0 1.3 1 0 0 1 1 1 0 Antigenic membrane protein of phytoplasma DUF3965 PF13112.6 CBZ24879.1 - 0.16 11.2 0.0 0.27 10.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3965) MCM_N PF14551.6 CBZ24879.1 - 1.2 9.8 5.4 3.3 8.3 0.2 3.0 3 0 0 3 3 3 0 MCM N-terminal domain Fez1 PF06818.15 CBZ24879.1 - 7 7.0 23.7 0.2 12.1 7.5 3.3 2 1 0 3 3 3 0 Fez1 PX PF00787.24 CBZ24880.1 - 4.3e-10 39.6 0.0 5.5e-09 36.0 0.0 2.4 2 0 0 2 2 2 1 PX domain Sec5 PF15469.6 CBZ24881.1 - 0.0043 16.9 0.0 0.0086 15.9 0.0 1.5 1 0 0 1 1 1 1 Exocyst complex component Sec5 FAM110_C PF14160.6 CBZ24881.1 - 0.26 12.4 3.5 2 9.5 3.5 2.7 1 0 0 1 1 1 0 Centrosome-associated C terminus HIT PF01230.23 CBZ24882.1 - 4e-22 78.8 0.1 5.1e-22 78.4 0.1 1.1 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.8 CBZ24882.1 - 5.7e-14 52.6 0.0 7.3e-14 52.2 0.0 1.1 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding CwfJ_C_1 PF04677.15 CBZ24882.1 - 0.052 13.4 5.2 0.092 12.6 3.3 2.3 2 1 0 2 2 2 0 Protein similar to CwfJ C-terminus 1 YcxB PF14317.6 CBZ24882.1 - 0.077 12.7 0.0 6.7 6.5 0.0 2.5 2 0 0 2 2 2 0 YcxB-like protein TRAP-gamma PF07074.12 CBZ24883.1 - 2e-07 30.8 1.9 0.003 17.1 0.2 2.1 2 0 0 2 2 2 2 Translocon-associated protein, gamma subunit (TRAP-gamma) DUF4386 PF14329.6 CBZ24883.1 - 0.014 15.3 1.2 0.025 14.4 1.3 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4386) DUF2157 PF09925.9 CBZ24883.1 - 0.049 13.4 0.6 0.073 12.9 0.6 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2157) MARVEL PF01284.23 CBZ24883.1 - 0.083 12.9 2.5 0.14 12.2 2.5 1.4 1 1 0 1 1 1 0 Membrane-associating domain VWA_3 PF13768.6 CBZ24884.1 - 4.6e-09 36.4 0.1 9.9e-09 35.3 0.1 1.6 1 0 0 1 1 1 1 von Willebrand factor type A domain VIT_2 PF13757.6 CBZ24884.1 - 0.0037 17.1 0.0 0.011 15.6 0.0 1.8 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain Na_Ca_ex PF01699.24 CBZ24885.1 - 2.8e-08 33.8 32.5 8.8e-06 25.8 5.5 3.2 3 1 0 3 3 3 2 Sodium/calcium exchanger protein Med3 PF11593.8 CBZ24886.1 - 2.7 7.1 10.2 4.6 6.3 10.2 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Proteasome PF00227.26 CBZ24889.1 - 1.5e-50 171.3 0.0 2e-50 170.9 0.0 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 CBZ24889.1 - 4.2e-13 48.7 0.3 7.3e-13 47.9 0.3 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature AA_permease_2 PF13520.6 CBZ24890.1 - 7e-34 117.4 41.2 7.7e-34 117.2 40.5 1.4 1 1 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 CBZ24890.1 - 6.7e-13 48.0 34.9 2e-12 46.5 34.9 1.7 1 1 0 1 1 1 1 Amino acid permease DUF2207 PF09972.9 CBZ24890.1 - 3.7 6.2 6.9 0.67 8.7 0.0 2.4 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) Aa_trans PF01490.18 CBZ24891.1 - 1.6e-21 76.5 20.6 2.3e-21 76.0 20.6 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein EspB PF05802.11 CBZ24891.1 - 1.1 9.2 2.9 1.8 8.5 2.9 1.3 1 0 0 1 1 1 0 Enterobacterial EspB protein IPK PF03770.16 CBZ24892.1 - 8.6e-43 146.5 0.2 1.4e-42 145.8 0.2 1.4 1 0 0 1 1 1 1 Inositol polyphosphate kinase Tau95_N PF17682.1 CBZ24892.1 - 0.022 15.0 0.0 0.075 13.2 0.0 1.9 1 0 0 1 1 1 0 Tau95 Triple barrel domain Thr_synth_N PF14821.6 CBZ24893.1 - 6e-14 52.0 0.5 3.2e-13 49.7 0.0 2.5 4 0 0 4 4 4 1 Threonine synthase N terminus PALP PF00291.25 CBZ24893.1 - 3e-09 36.7 0.0 7.9e-09 35.3 0.0 1.7 1 1 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme LXG PF04740.12 CBZ24893.1 - 0.067 12.9 0.0 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 LXG domain of WXG superfamily zf-CW PF07496.15 CBZ24894.1 - 0.0019 18.2 3.2 0.0019 18.2 3.2 1.7 2 0 0 2 2 2 1 CW-type Zinc Finger Choline_transpo PF04515.12 CBZ24896.1 - 2.5e-52 178.1 41.4 2.5e-52 178.1 41.4 1.8 2 0 0 2 2 2 1 Plasma-membrane choline transporter ATP-synt_S1 PF05827.12 CBZ24896.1 - 0.13 12.1 2.9 0.18 11.6 0.0 2.3 2 0 0 2 2 2 0 Vacuolar ATP synthase subunit S1 (ATP6S1) Ntox27 PF15531.6 CBZ24900.1 - 0.016 15.1 0.1 0.038 13.9 0.1 1.6 1 1 0 1 1 1 0 Bacterial toxin 27 UTP25 PF06862.12 CBZ24901.1 - 5.1e-111 371.8 0.2 3.8e-102 342.5 0.2 2.1 2 0 0 2 2 2 2 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 Dzip-like_N PF13815.6 CBZ24902.1 - 3.4e-39 133.5 4.2 3.4e-39 133.5 4.2 2.6 3 0 0 3 3 3 1 Iguana/Dzip1-like DAZ-interacting protein N-terminal zf-Di19 PF05605.12 CBZ24902.1 - 0.00038 20.7 0.1 0.00074 19.8 0.1 1.4 1 0 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding ANAPC_CDC26 PF10471.9 CBZ24902.1 - 0.0073 17.1 1.2 0.0073 17.1 1.2 4.2 4 0 0 4 4 4 1 Anaphase-promoting complex APC subunit CDC26 zf-C2H2_4 PF13894.6 CBZ24902.1 - 0.017 15.9 1.2 0.036 14.9 1.2 1.6 1 0 0 1 1 1 0 C2H2-type zinc finger zf-C2H2_2 PF12756.7 CBZ24902.1 - 0.086 13.2 0.6 0.57 10.5 0.1 2.2 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-C2H2 PF00096.26 CBZ24902.1 - 0.17 12.4 1.4 0.32 11.5 1.4 1.5 1 0 0 1 1 1 0 Zinc finger, C2H2 type Tmemb_9 PF05434.11 CBZ24902.1 - 8.1 6.3 5.8 0.59 10.0 0.2 1.9 2 0 0 2 2 2 0 TMEM9 DUF4407 PF14362.6 CBZ24902.1 - 8.3 5.7 12.8 0.43 9.9 3.4 2.2 2 1 0 2 2 2 0 Domain of unknown function (DUF4407) mRNA_triPase PF02940.15 CBZ24903.1 - 1.3e-08 34.9 0.0 0.00024 20.9 0.0 2.7 3 0 0 3 3 3 2 mRNA capping enzyme, beta chain Pyr_redox_2 PF07992.14 CBZ24904.1 - 2.5e-17 63.0 0.0 3.9e-16 59.1 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 CBZ24904.1 - 3.3e-10 40.4 0.0 1.1e-06 29.1 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 CBZ24904.1 - 8.4e-06 25.6 0.0 0.033 13.8 0.0 2.4 2 0 0 2 2 2 2 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 CBZ24904.1 - 2.6e-05 23.5 0.0 0.015 14.3 0.0 3.1 3 0 0 3 3 3 1 Lycopene cyclase protein NAD_binding_9 PF13454.6 CBZ24904.1 - 7.1e-05 22.9 0.0 0.083 12.9 0.0 3.4 3 0 0 3 3 3 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 CBZ24904.1 - 7.4e-05 22.9 0.8 0.43 10.8 0.0 2.9 3 0 0 3 3 2 2 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 CBZ24904.1 - 0.0017 17.6 0.0 0.0073 15.5 0.0 1.9 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Thi4 PF01946.17 CBZ24904.1 - 0.002 17.4 0.0 0.06 12.6 0.0 2.5 2 0 0 2 2 2 1 Thi4 family NAD_binding_7 PF13241.6 CBZ24904.1 - 0.0039 17.6 0.0 1.1 9.8 0.0 2.5 2 0 0 2 2 2 1 Putative NAD(P)-binding FAD_binding_3 PF01494.19 CBZ24904.1 - 0.088 12.0 0.0 0.79 8.9 0.0 2.1 2 0 0 2 2 2 0 FAD binding domain NAD_Gly3P_dh_N PF01210.23 CBZ24904.1 - 0.091 12.7 0.0 0.18 11.8 0.0 1.5 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus GIDA PF01134.22 CBZ24904.1 - 0.15 11.1 0.0 13 4.7 0.0 2.8 3 0 0 3 3 3 0 Glucose inhibited division protein A 3HCDH_N PF02737.18 CBZ24904.1 - 0.15 11.9 0.0 0.66 9.8 0.0 2.0 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain SbsC_C PF18058.1 CBZ24904.1 - 0.18 12.0 0.1 0.44 10.8 0.1 1.5 1 0 0 1 1 1 0 SbsC C-terminal domain CS PF04969.16 CBZ24905.1 - 2.5e-16 60.4 0.1 4.7e-16 59.6 0.1 1.5 1 0 0 1 1 1 1 CS domain Nudc_N PF14050.6 CBZ24905.1 - 6.2e-15 54.9 0.2 1.5e-14 53.7 0.2 1.7 1 0 0 1 1 1 1 N-terminal conserved domain of Nudc. DUF5486 PF17588.2 CBZ24905.1 - 0.12 12.2 3.8 8.1 6.4 0.5 2.9 2 0 0 2 2 2 0 Family of unknown function (DUF5486) Lge1 PF11488.8 CBZ24905.1 - 0.69 10.1 11.5 4.3 7.6 0.1 3.0 2 1 0 2 2 2 0 Transcriptional regulatory protein LGE1 Hid1 PF12722.7 CBZ24905.1 - 2.5 6.1 8.7 0.059 11.5 2.8 1.3 2 0 0 2 2 2 0 High-temperature-induced dauer-formation protein CNDH2_M PF16869.5 CBZ24905.1 - 2.5 8.8 10.3 0.31 11.7 5.5 1.8 2 0 0 2 2 2 0 PF16858 Cys_Met_Meta_PP PF01053.20 CBZ24906.1 - 1.3e-115 386.0 0.0 1.6e-115 385.7 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 CBZ24906.1 - 0.0011 18.3 0.0 0.0017 17.6 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 CBZ24906.1 - 0.011 14.7 0.1 0.016 14.2 0.1 1.2 1 0 0 1 1 1 0 Aminotransferase class-V Amastin PF07344.11 CBZ24908.1 - 4.9e-06 26.5 12.2 4.9e-06 26.5 12.2 2.4 1 1 1 2 2 2 1 Amastin surface glycoprotein SUR7 PF06687.12 CBZ24908.1 - 0.0087 15.7 14.5 0.25 11.0 8.1 2.6 2 1 1 3 3 3 2 SUR7/PalI family Amastin PF07344.11 CBZ24909.1 - 5e-06 26.5 12.2 5e-06 26.5 12.2 2.4 1 1 1 2 2 2 1 Amastin surface glycoprotein SUR7 PF06687.12 CBZ24909.1 - 0.0096 15.6 14.6 0.26 10.9 8.2 2.6 2 1 1 3 3 3 2 SUR7/PalI family UPF0242 PF06785.11 CBZ24910.1 - 0.033 14.3 5.1 0.67 10.0 0.1 2.7 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0242) N-terminus RPW8 PF05659.11 CBZ24910.1 - 0.15 11.8 0.2 21 4.8 0.0 3.1 3 0 0 3 3 3 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 GIT_CC PF16559.5 CBZ24910.1 - 0.21 11.5 1.8 6.6 6.7 0.1 3.0 2 0 0 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor Spc7 PF08317.11 CBZ24910.1 - 3.3 6.5 12.4 2.5 6.9 0.2 3.1 3 0 0 3 3 3 0 Spc7 kinetochore protein DUF4201 PF13870.6 CBZ24910.1 - 5.6 6.7 9.0 12 5.6 1.4 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4201) FA_desaturase PF00487.24 CBZ24911.1 - 4.4e-16 59.5 19.4 4.4e-16 59.5 19.4 1.6 1 1 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.28 CBZ24911.1 - 3.3e-10 39.9 0.0 3.5e-09 36.7 0.0 2.2 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain FemAB PF02388.16 CBZ24912.1 - 0.037 12.9 2.3 0.042 12.7 2.3 1.0 1 0 0 1 1 1 0 FemAB family Rotamase PF00639.21 CBZ24912.1 - 0.049 14.6 0.3 0.062 14.3 0.3 1.2 1 0 0 1 1 1 0 PPIC-type PPIASE domain Ion_trans_2 PF07885.16 CBZ24913.1 - 2.1e-09 37.2 6.7 7.1e-09 35.5 6.7 1.9 1 0 0 1 1 1 1 Ion channel Ion_trans_2 PF07885.16 CBZ24914.1 - 5e-11 42.4 8.5 5e-11 42.4 8.5 2.2 2 0 0 2 2 2 1 Ion channel Lig_chan PF00060.26 CBZ24914.1 - 5e-05 23.2 1.3 0.00013 21.8 1.3 1.9 1 1 0 1 1 1 1 Ligand-gated ion channel Ion_trans PF00520.31 CBZ24914.1 - 0.0026 17.0 19.7 0.0026 17.0 19.7 2.2 2 1 0 2 2 2 1 Ion transport protein DUF515 PF04415.12 CBZ24915.1 - 0.24 9.7 0.2 0.37 9.1 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF515) T2SSM PF04612.12 CBZ24916.1 - 0.55 10.3 3.9 0.52 10.3 1.5 1.9 1 1 1 2 2 2 0 Type II secretion system (T2SS), protein M WD40 PF00400.32 CBZ24917.1 - 1.4e-23 82.7 13.1 0.0027 18.5 0.0 10.6 11 1 0 11 11 11 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBZ24917.1 - 7.8e-09 35.7 0.1 8.6 6.7 0.0 8.3 6 2 1 8 8 8 2 Anaphase-promoting complex subunit 4 WD40 domain Utp12 PF04003.12 CBZ24917.1 - 4.4e-07 30.2 0.2 8e-07 29.3 0.2 1.4 1 0 0 1 1 1 1 Dip2/Utp12 Family Ge1_WD40 PF16529.5 CBZ24917.1 - 0.12 11.3 1.2 20 4.0 0.1 4.1 2 2 2 4 4 4 0 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 CBZ24917.1 - 0.21 10.9 0.0 6.1 6.1 0.0 2.5 2 0 0 2 2 2 0 WD40-like domain Complex1_LYR PF05347.15 CBZ24918.1 - 0.00024 21.1 0.3 0.00043 20.3 0.3 1.5 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 CBZ24918.1 - 0.032 15.0 0.3 0.054 14.2 0.3 1.4 1 0 0 1 1 1 0 Complex1_LYR-like SpoU_methylase PF00588.19 CBZ24920.1 - 1.5e-09 38.2 0.0 0.0022 18.2 0.0 2.3 2 0 0 2 2 2 2 SpoU rRNA Methylase family Nrap_D2 PF17403.2 CBZ24920.1 - 0.076 12.8 0.0 0.13 12.0 0.0 1.3 1 0 0 1 1 1 0 Nrap protein PAP/OAS-like domain CDC45 PF02724.14 CBZ24921.1 - 0.03 12.6 1.4 0.047 12.0 1.4 1.2 1 0 0 1 1 1 0 CDC45-like protein Spt5_N PF11942.8 CBZ24921.1 - 0.17 12.9 7.9 0.06 14.3 4.1 2.1 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal zf-LSD1 PF06943.12 CBZ24923.1 - 9.7e-07 28.5 10.3 9.7e-07 28.5 10.3 3.0 2 1 1 3 3 3 2 LSD1 zinc finger PHD PF00628.29 CBZ24923.1 - 0.034 14.0 1.4 0.034 14.0 1.4 2.3 3 0 0 3 3 3 0 PHD-finger C1_1 PF00130.22 CBZ24923.1 - 6 6.8 11.2 10 6.1 1.7 2.3 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) ELO PF01151.18 CBZ24924.1 - 7.7e-36 123.9 13.2 9.6e-36 123.6 13.2 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family ELO PF01151.18 CBZ24925.1 - 2.1e-66 224.0 9.9 2.1e-66 224.0 9.9 1.6 2 0 0 2 2 2 1 GNS1/SUR4 family PRIMA1 PF16101.5 CBZ24925.1 - 0.22 11.6 1.8 0.48 10.5 1.8 1.5 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 ELO PF01151.18 CBZ24926.1 - 1.4e-61 208.2 15.0 1.6e-61 208.0 15.0 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family GTA_holin_3TM PF11351.8 CBZ24926.1 - 0.23 12.0 1.6 7.6 7.1 0.0 2.3 2 0 0 2 2 2 0 Holin of 3TMs, for gene-transfer release ELO PF01151.18 CBZ24927.1 - 4.1e-61 206.7 15.4 4.7e-61 206.5 15.4 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family ELO PF01151.18 CBZ24929.1 - 3.4e-68 229.9 5.1 4.1e-68 229.6 5.1 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family DUF3177 PF11375.8 CBZ24929.1 - 0.095 12.5 5.1 1.7 8.4 5.1 2.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3177) ELO PF01151.18 CBZ24930.1 - 8.9e-79 264.5 20.3 1e-78 264.3 20.3 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family ELO PF01151.18 CBZ24931.1 - 1.8e-80 270.1 23.0 2.1e-80 269.9 23.0 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family ELO PF01151.18 CBZ24932.1 - 4.6e-77 258.9 19.4 5.5e-77 258.7 19.4 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family Sdh_cyt PF01127.22 CBZ24932.1 - 1 9.4 11.0 0.076 13.1 5.9 1.8 2 1 0 2 2 2 0 Succinate dehydrogenase/Fumarate reductase transmembrane subunit ELO PF01151.18 CBZ24933.1 - 3.2e-74 249.6 8.5 4.1e-74 249.3 8.5 1.1 1 0 0 1 1 1 1 GNS1/SUR4 family Peptidase_U4 PF03419.13 CBZ24933.1 - 0.049 12.9 3.4 0.076 12.3 3.4 1.4 1 0 0 1 1 1 0 Sporulation factor SpoIIGA ELO PF01151.18 CBZ24934.1 - 1.5e-81 273.6 18.1 1.9e-81 273.3 18.1 1.1 1 0 0 1 1 1 1 GNS1/SUR4 family ELO PF01151.18 CBZ24935.1 - 6.2e-71 238.9 20.8 9.1e-71 238.3 20.8 1.2 1 0 0 1 1 1 1 GNS1/SUR4 family ELO PF01151.18 CBZ24936.1 - 2.1e-74 250.2 22.0 2.4e-74 250.0 22.0 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family Ras PF00071.22 CBZ24938.1 - 1.5e-35 122.2 0.0 1.9e-35 121.9 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CBZ24938.1 - 2.1e-26 92.5 0.0 3.2e-26 91.9 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CBZ24938.1 - 1.2e-08 34.6 0.0 1.7e-08 34.1 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 CBZ24938.1 - 6.9e-05 22.3 0.0 9.5e-05 21.9 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 CBZ24938.1 - 0.0022 18.1 0.0 0.0053 16.8 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 CBZ24938.1 - 0.024 15.0 0.3 0.13 12.6 0.3 2.1 1 1 0 1 1 1 0 AAA ATPase domain AAA_7 PF12775.7 CBZ24938.1 - 0.047 13.2 0.0 0.077 12.5 0.0 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_24 PF13479.6 CBZ24938.1 - 0.077 12.7 0.0 0.12 12.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 CBZ24938.1 - 0.078 12.9 0.0 0.17 11.8 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase AAA_22 PF13401.6 CBZ24938.1 - 0.11 12.8 0.0 0.24 11.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 CBZ24938.1 - 0.15 11.9 0.0 0.25 11.2 0.0 1.3 1 0 0 1 1 1 0 NACHT domain TniB PF05621.11 CBZ24938.1 - 0.18 11.2 0.0 0.34 10.3 0.0 1.4 1 0 0 1 1 1 0 Bacterial TniB protein RVT_2 PF07727.14 CBZ24939.1 - 0.091 12.4 0.0 0.13 11.9 0.0 1.2 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) Ribosomal_L21p PF00829.21 CBZ24940.1 - 3.7e-19 68.9 0.0 4.7e-19 68.5 0.0 1.1 1 0 0 1 1 1 1 Ribosomal prokaryotic L21 protein PsbP PF01789.16 CBZ24940.1 - 0.039 14.1 0.1 0.07 13.3 0.1 1.3 1 0 0 1 1 1 0 PsbP Glyco_hydro_67N PF03648.14 CBZ24941.1 - 0.64 10.3 5.6 1.1 9.6 0.8 3.7 4 0 0 4 4 4 0 Glycosyl hydrolase family 67 N-terminus DUF1682 PF07946.14 CBZ24942.1 - 0.064 12.5 1.6 0.095 11.9 1.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) DUF2397 PF09660.10 CBZ24942.1 - 0.35 9.7 7.5 0.52 9.2 7.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2397) Kinesin PF00225.23 CBZ24943.1 - 3.9e-91 305.4 0.2 6.5e-91 304.7 0.2 1.3 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 CBZ24943.1 - 1.1e-18 67.5 0.0 5.6e-18 65.3 0.0 2.1 1 1 0 1 1 1 1 Microtubule binding DUF5327 PF17261.2 CBZ24943.1 - 5 7.9 6.2 74 4.2 5.4 3.0 2 0 0 2 2 2 0 Family of unknown function (DUF5327) DUF4201 PF13870.6 CBZ24944.1 - 6.5e-32 110.7 15.8 6.5e-32 110.7 15.8 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4201) JIP_LZII PF16471.5 CBZ24944.1 - 0.0048 17.0 0.3 0.0048 17.0 0.3 4.6 4 2 2 6 6 6 2 JNK-interacting protein leucine zipper II KxDL PF10241.9 CBZ24944.1 - 0.015 15.6 2.2 0.015 15.6 2.2 3.2 3 1 1 4 4 4 0 Uncharacterized conserved protein LURAP PF14854.6 CBZ24944.1 - 1.6 8.7 10.6 6.1 6.8 0.2 3.7 4 0 0 4 4 4 0 Leucine rich adaptor protein Pkinase PF00069.25 CBZ24945.1 - 1.5e-41 142.5 0.0 6.6e-23 81.4 0.0 2.7 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ24945.1 - 5e-13 48.9 0.0 9.1e-09 35.0 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.23 CBZ24945.1 - 0.00064 19.7 0.0 0.0014 18.6 0.0 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 CBZ24945.1 - 0.061 12.9 0.0 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 RIO1 family Choline_kinase PF01633.20 CBZ24945.1 - 0.089 12.4 0.0 0.14 11.7 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase SNF2_N PF00176.23 CBZ24946.1 - 2.8e-59 200.6 0.0 5.4e-59 199.7 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 CBZ24946.1 - 9.8e-19 67.7 0.0 8.5e-18 64.7 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 CBZ24946.1 - 2.2e-08 34.3 0.0 4.6e-08 33.2 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 CBZ24946.1 - 1.7e-05 24.7 0.0 5.1e-05 23.1 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase DUF1935 PF09149.10 CBZ24947.1 - 3.6e-40 136.5 0.3 4e-40 136.4 0.3 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1935) TIG_2 PF18020.1 CBZ24947.1 - 0.079 13.6 0.3 2.6 8.7 0.1 2.1 1 1 1 2 2 2 0 TIG domain found in plexin DUF1935 PF09149.10 CBZ24948.1 - 3.6e-40 136.5 0.3 4e-40 136.4 0.3 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1935) TIG_2 PF18020.1 CBZ24948.1 - 0.079 13.6 0.3 2.6 8.7 0.1 2.1 1 1 1 2 2 2 0 TIG domain found in plexin PP2C PF00481.21 CBZ24952.1 - 6.7e-49 166.8 0.0 4.1e-48 164.3 0.0 2.0 1 1 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 CBZ24952.1 - 9.5e-07 28.7 0.3 4.5e-06 26.5 0.3 2.0 1 1 0 1 1 1 1 Protein phosphatase 2C GSH_synth_ATP PF03917.17 CBZ24953.1 - 4.2e-66 223.2 0.0 5.9e-66 222.8 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic glutathione synthase, ATP binding domain GSH_synthase PF03199.15 CBZ24953.1 - 7.6e-30 103.4 0.3 1.6e-29 102.4 0.3 1.6 1 0 0 1 1 1 1 Eukaryotic glutathione synthase CbiJ PF02571.14 CBZ24953.1 - 0.0029 17.1 0.2 0.0057 16.2 0.2 1.4 1 0 0 1 1 1 1 Precorrin-6x reductase CbiJ/CobK Ribonuc_P_40 PF08584.11 CBZ24953.1 - 0.081 12.2 0.2 0.13 11.5 0.2 1.3 1 0 0 1 1 1 0 Ribonuclease P 40kDa (Rpp40) subunit DNA_pol_A PF00476.20 CBZ24954.1 - 4e-38 131.5 0.0 2.5e-37 128.8 0.0 2.1 2 1 0 2 2 2 1 DNA polymerase family A Bile_Hydr_Trans PF04775.14 CBZ24954.1 - 0.034 14.2 0.1 4 7.5 0.0 3.5 4 0 0 4 4 4 0 Acyl-CoA thioester hydrolase/BAAT N-terminal region Mito_fiss_reg PF05308.11 CBZ24955.1 - 0.011 15.9 0.4 0.011 15.9 0.4 2.8 2 0 0 2 2 2 0 Mitochondrial fission regulator SlyX PF04102.12 CBZ24955.1 - 1 10.0 10.6 5.1 7.8 0.2 4.3 3 1 1 4 4 4 0 SlyX Nnf1 PF03980.14 CBZ24955.1 - 7.6 7.0 10.3 0.98 9.8 1.7 3.3 3 0 0 3 3 3 0 Nnf1 Ribosomal_L16 PF00252.18 CBZ24957.1 - 4.3e-16 59.1 0.0 5.1e-16 58.9 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e PAP_assoc PF03828.19 CBZ24958.1 - 1.6e-16 60.3 0.0 2.6e-11 43.5 0.0 2.9 3 0 0 3 3 3 2 Cid1 family poly A polymerase zf-MYST PF17772.1 CBZ24958.1 - 0.04 13.5 0.1 0.079 12.6 0.1 1.4 1 0 0 1 1 1 0 MYST family zinc finger domain NTP_transf_2 PF01909.23 CBZ24958.1 - 0.14 12.5 0.0 0.35 11.2 0.0 1.6 1 0 0 1 1 1 0 Nucleotidyltransferase domain PRK PF00485.18 CBZ24959.1 - 6.9e-08 32.5 0.0 6.8e-05 22.7 0.0 2.1 2 0 0 2 2 2 2 Phosphoribulokinase / Uridine kinase family AAA_18 PF13238.6 CBZ24959.1 - 0.00024 21.7 0.0 0.28 11.7 0.0 2.4 2 1 0 2 2 2 2 AAA domain AAA_25 PF13481.6 CBZ24959.1 - 0.0014 18.2 0.0 0.0022 17.6 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 CBZ24959.1 - 0.0051 17.2 0.0 0.0078 16.6 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain AAA_30 PF13604.6 CBZ24959.1 - 0.0091 15.7 0.0 0.015 15.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 CBZ24959.1 - 0.012 14.9 0.4 0.058 12.7 0.1 2.3 2 1 1 3 3 3 0 Zeta toxin dNK PF01712.19 CBZ24959.1 - 0.015 15.2 0.0 3.1 7.6 0.0 2.3 2 0 0 2 2 2 0 Deoxynucleoside kinase Ploopntkinase3 PF18751.1 CBZ24959.1 - 0.019 14.9 0.0 0.044 13.7 0.0 1.6 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 MMR_HSR1 PF01926.23 CBZ24959.1 - 0.031 14.4 0.0 0.067 13.3 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase ABC_tran PF00005.27 CBZ24959.1 - 0.036 14.6 0.0 0.062 13.8 0.0 1.3 1 0 0 1 1 1 0 ABC transporter NACHT PF05729.12 CBZ24959.1 - 0.055 13.4 0.0 0.13 12.2 0.0 1.6 1 0 0 1 1 1 0 NACHT domain RNA_helicase PF00910.22 CBZ24959.1 - 0.058 13.8 0.0 0.12 12.8 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_29 PF13555.6 CBZ24959.1 - 0.07 12.9 0.0 0.17 11.6 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_17 PF13207.6 CBZ24959.1 - 0.078 13.4 0.0 6.6 7.2 0.0 2.4 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.15 CBZ24959.1 - 0.091 12.7 0.0 0.18 11.7 0.0 1.5 1 0 0 1 1 1 0 NTPase KTI12 PF08433.10 CBZ24959.1 - 0.1 12.0 0.0 0.21 11.0 0.0 1.5 1 0 0 1 1 1 0 Chromatin associated protein KTI12 AAA_33 PF13671.6 CBZ24959.1 - 0.11 12.6 0.0 0.88 9.7 0.0 2.2 2 0 0 2 2 2 0 AAA domain MeaB PF03308.16 CBZ24959.1 - 0.12 11.3 0.0 0.2 10.6 0.0 1.3 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_22 PF13401.6 CBZ24959.1 - 0.14 12.4 0.0 0.29 11.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain TERF2_RBM PF16772.5 CBZ24959.1 - 0.2 11.1 0.0 0.38 10.2 0.0 1.4 1 0 0 1 1 1 0 Telomeric repeat-binding factor 2 Rap1-binding motif Na_H_Exchanger PF00999.21 CBZ24960.1 - 3.3e-18 65.6 24.8 6e-18 64.8 24.8 1.4 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Mito_carr PF00153.27 CBZ24961.1 - 1.8e-24 85.5 1.6 1.2e-11 44.4 0.0 3.3 2 1 1 3 3 3 3 Mitochondrial carrier protein Mito_carr PF00153.27 CBZ24962.1 - 9e-08 31.9 0.1 0.036 14.0 0.0 3.6 3 0 0 3 3 3 3 Mitochondrial carrier protein Sulfotransfer_3 PF13469.6 CBZ24965.1 - 5.4e-06 26.9 0.0 8.8e-06 26.3 0.0 1.5 1 0 0 1 1 1 1 Sulfotransferase family DUF202 PF02656.15 CBZ24966.1 - 4.8e-17 62.2 0.6 3.9e-16 59.2 0.1 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF202) COQ9 PF08511.11 CBZ24968.1 - 2.9e-07 30.2 0.0 2.5e-06 27.2 0.0 2.3 2 0 0 2 2 2 1 COQ9 FTA4 PF13093.6 CBZ24968.1 - 0.084 12.8 0.0 0.12 12.3 0.0 1.3 1 0 0 1 1 1 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 AAA_6 PF12774.7 CBZ24969.1 - 6.7e-141 469.0 0.1 4.9e-139 462.9 0.0 3.4 4 0 0 4 4 4 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 CBZ24969.1 - 1.1e-108 364.0 0.7 1.1e-108 364.0 0.7 3.1 4 0 0 4 4 4 1 Dynein heavy chain, N-terminal region 2 AAA_8 PF12780.7 CBZ24969.1 - 9.9e-92 306.9 0.0 3.7e-91 305.1 0.0 2.1 2 0 0 2 2 2 1 P-loop containing dynein motor region D4 Dynein_C PF18199.1 CBZ24969.1 - 2.8e-81 273.1 0.1 2.9e-80 269.7 0.0 2.6 2 0 0 2 2 2 1 Dynein heavy chain C-terminal domain AAA_9 PF12781.7 CBZ24969.1 - 1.9e-71 239.7 0.3 1.9e-71 239.7 0.3 2.9 4 0 0 4 4 3 1 ATP-binding dynein motor region AAA_7 PF12775.7 CBZ24969.1 - 1.3e-55 187.7 1.6 1.2e-50 171.6 0.0 4.4 4 0 0 4 4 4 2 P-loop containing dynein motor region MT PF12777.7 CBZ24969.1 - 1.5e-44 152.5 3.9 1.5e-44 152.5 3.9 1.9 2 0 0 2 2 2 1 Microtubule-binding stalk of dynein motor Dynein_heavy PF03028.15 CBZ24969.1 - 3.6e-39 133.5 0.0 7.2e-37 126.1 0.0 3.6 3 0 0 3 3 3 1 Dynein heavy chain region D6 P-loop domain AAA_lid_11 PF18198.1 CBZ24969.1 - 8.2e-28 97.3 0.0 4.5e-27 94.9 0.0 2.3 2 0 0 2 2 2 1 Dynein heavy chain AAA lid domain AAA_5 PF07728.14 CBZ24969.1 - 2.9e-20 72.7 2.1 2.9e-05 24.1 0.0 5.9 5 1 0 5 5 5 4 AAA domain (dynein-related subfamily) AAA_lid_1 PF17857.1 CBZ24969.1 - 5.5e-17 61.8 0.0 1.8e-16 60.2 0.0 1.9 1 0 0 1 1 1 1 AAA+ lid domain Dynein_AAA_lid PF17852.1 CBZ24969.1 - 1.8e-15 57.2 0.0 4.7e-14 52.6 0.0 3.3 2 1 0 2 2 2 1 Dynein heavy chain AAA lid domain AAA_16 PF13191.6 CBZ24969.1 - 9.3e-05 22.9 14.0 0.28 11.6 0.0 6.6 7 0 0 7 7 5 2 AAA ATPase domain AAA_22 PF13401.6 CBZ24969.1 - 0.00014 22.1 19.4 0.015 15.6 0.0 7.9 7 1 0 8 8 8 1 AAA domain DUF815 PF05673.13 CBZ24969.1 - 0.00076 18.7 0.0 0.54 9.4 0.0 3.1 3 0 0 3 3 3 1 Protein of unknown function (DUF815) AAA PF00004.29 CBZ24969.1 - 0.0015 18.9 1.2 2 8.8 0.0 4.3 4 0 0 4 4 4 1 ATPase family associated with various cellular activities (AAA) T2SSE PF00437.20 CBZ24969.1 - 0.0017 17.5 2.6 0.021 13.9 0.3 3.0 3 0 0 3 3 3 1 Type II/IV secretion system protein M16C_assoc PF08367.11 CBZ24969.1 - 0.0019 17.4 1.7 0.025 13.7 0.2 2.6 2 0 0 2 2 2 1 Peptidase M16C associated AAA_29 PF13555.6 CBZ24969.1 - 0.0031 17.2 1.7 4.1 7.2 0.1 3.8 3 0 0 3 3 3 1 P-loop containing region of AAA domain Mg_chelatase PF01078.21 CBZ24969.1 - 0.021 14.2 2.0 4.7 6.5 0.1 4.2 4 0 0 4 4 4 0 Magnesium chelatase, subunit ChlI AAA_18 PF13238.6 CBZ24969.1 - 0.041 14.4 4.1 4.8 7.7 0.0 4.9 6 0 0 6 6 4 0 AAA domain RNA_helicase PF00910.22 CBZ24969.1 - 0.16 12.3 0.3 19 5.7 0.0 4.2 4 0 0 4 4 4 0 RNA helicase FtsK_SpoIIIE PF01580.18 CBZ24969.1 - 0.22 10.8 2.4 2.3 7.5 0.1 3.3 3 0 0 3 3 3 0 FtsK/SpoIIIE family Hrs_helical PF12210.8 CBZ24969.1 - 1.3 9.6 13.9 8.6 7.0 0.6 4.2 2 1 1 3 3 3 0 Hepatocyte growth factor-regulated tyrosine kinase substrate V_ATPase_I PF01496.19 CBZ24969.1 - 5.2 4.9 12.7 0.15 9.9 3.7 2.1 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family Pkinase PF00069.25 CBZ24970.1 - 7.2e-44 150.1 0.0 3.9e-43 147.7 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ24970.1 - 2.6e-17 63.0 0.0 4.3e-16 59.0 0.0 2.3 2 0 0 2 2 2 1 Protein tyrosine kinase PQ-loop PF04193.14 CBZ24972.1 - 4.1e-26 90.5 6.5 5.1e-13 48.6 0.3 2.4 2 0 0 2 2 2 2 PQ loop repeat Kinesin PF00225.23 CBZ24973.1 - 1.4e-102 343.1 0.0 6.7e-102 340.8 0.0 2.4 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 CBZ24973.1 - 1e-19 70.9 0.0 3.1e-19 69.4 0.0 1.9 1 0 0 1 1 1 1 Microtubule binding Kinesin PF00225.23 CBZ24974.1 - 9.5e-101 337.0 3.6 1.4e-99 333.2 0.0 2.6 2 0 0 2 2 2 1 Kinesin motor domain Spc7 PF08317.11 CBZ24974.1 - 2.1e-33 115.6 336.0 0.00033 19.7 14.0 17.2 1 1 16 19 19 18 17 Spc7 kinetochore protein ATG16 PF08614.11 CBZ24974.1 - 1.1e-28 100.9 372.8 0.0098 16.1 22.5 18.3 1 1 17 18 18 16 16 Autophagy protein 16 (ATG16) Microtub_bd PF16796.5 CBZ24974.1 - 7.1e-20 71.5 0.0 2.4e-19 69.8 0.0 2.0 1 0 0 1 1 1 1 Microtubule binding Myosin_tail_1 PF01576.19 CBZ24974.1 - 5.6e-17 60.9 348.4 3.2e-07 28.6 55.5 8.7 1 1 7 8 8 7 7 Myosin tail HMMR_N PF15905.5 CBZ24974.1 - 1.5e-16 60.8 308.5 0.00024 20.7 45.1 10.1 1 1 7 9 9 8 8 Hyaluronan mediated motility receptor N-terminal Jnk-SapK_ap_N PF09744.9 CBZ24974.1 - 7.7e-14 52.2 376.9 0.14 12.4 18.3 21.5 1 1 22 24 24 22 14 JNK_SAPK-associated protein-1 APG6_N PF17675.1 CBZ24974.1 - 2.1e-12 47.7 417.4 0.41 11.2 17.3 23.3 1 1 19 20 20 16 11 Apg6 coiled-coil region TPR_MLP1_2 PF07926.12 CBZ24974.1 - 1.3e-07 31.8 406.1 0.14 12.2 20.9 20.4 1 1 25 26 26 22 20 TPR/MLP1/MLP2-like protein Flagellin_C PF00700.21 CBZ24974.1 - 1.3e-06 28.7 75.1 26 5.3 0.2 21.4 9 2 10 24 24 24 0 Bacterial flagellin C-terminal helical region LigT_PEase PF02834.16 CBZ24974.1 - 3.1e-05 24.1 55.6 2.7 8.2 1.0 11.1 7 2 3 10 10 10 4 LigT like Phosphoesterase MscS_porin PF12795.7 CBZ24974.1 - 0.00091 18.8 254.4 0.44 10.0 6.5 20.3 1 1 18 20 20 18 9 Mechanosensitive ion channel porin domain KASH_CCD PF14662.6 CBZ24974.1 - 0.0011 18.9 321.8 0.18 11.7 14.3 18.2 1 1 19 20 20 19 11 Coiled-coil region of CCDC155 or KASH DUF3467 PF11950.8 CBZ24974.1 - 0.0021 18.2 23.7 71 3.7 0.1 10.0 9 1 1 10 10 10 0 Protein of unknown function (DUF3467) Taxilin PF09728.9 CBZ24974.1 - 0.0027 16.9 338.9 0.057 12.6 10.8 19.2 1 1 17 22 22 20 16 Myosin-like coiled-coil protein CALCOCO1 PF07888.11 CBZ24974.1 - 0.0071 15.3 345.3 0.025 13.5 9.0 11.2 1 1 14 15 15 14 11 Calcium binding and coiled-coil domain (CALCOCO1) like DUF2524 PF10732.9 CBZ24974.1 - 0.59 10.5 220.5 4.3 7.7 1.2 28.5 10 4 21 32 32 30 0 Protein of unknown function (DUF2524) Kinesin PF00225.23 CBZ24975.1 - 1.3e-102 343.2 0.0 3.4e-102 341.8 0.0 1.8 1 0 0 1 1 1 1 Kinesin motor domain UPF0242 PF06785.11 CBZ24975.1 - 2.9e-30 105.8 449.1 0.014 15.6 11.6 24.4 4 4 20 25 25 25 23 Uncharacterised protein family (UPF0242) N-terminus TolA_bind_tri PF16331.5 CBZ24975.1 - 6.9e-24 83.7 363.1 0.97 9.6 0.6 44.0 6 4 30 45 45 45 27 TolA binding protein trimerisation Microtub_bd PF16796.5 CBZ24975.1 - 3.6e-18 65.9 0.0 1.1e-17 64.3 0.0 1.9 1 0 0 1 1 1 1 Microtubule binding MscS_porin PF12795.7 CBZ24975.1 - 3.4e-14 53.0 462.5 0.0068 16.0 39.4 15.4 5 3 8 15 15 14 12 Mechanosensitive ion channel porin domain HMMR_N PF15905.5 CBZ24975.1 - 3.1e-05 23.6 381.9 0.37 10.2 13.4 23.4 4 3 25 29 29 27 9 Hyaluronan mediated motility receptor N-terminal ERM PF00769.19 CBZ24975.1 - 0.0022 17.8 21.0 0.0022 17.8 21.0 16.0 4 2 13 18 18 10 1 Ezrin/radixin/moesin family DUF4201 PF13870.6 CBZ24975.1 - 0.0085 15.8 301.4 0.89 9.3 9.7 20.5 5 3 15 22 22 22 19 Domain of unknown function (DUF4201) Golgin_A5 PF09787.9 CBZ24975.1 - 0.015 14.8 427.8 0.079 12.4 17.0 18.0 4 3 15 19 19 18 0 Golgin subfamily A member 5 GIT_CC PF16559.5 CBZ24975.1 - 0.093 12.6 16.6 8.1 6.4 1.1 8.6 2 1 1 3 3 3 0 GIT coiled-coil Rho guanine nucleotide exchange factor COG5 PF10392.9 CBZ24975.1 - 2.5 8.3 119.9 19 5.5 1.5 24.6 4 3 33 37 37 36 0 Golgi transport complex subunit 5 WD40 PF00400.32 CBZ24976.1 - 0.025 15.4 4.7 2.1 9.3 0.1 3.8 3 0 0 3 3 3 0 WD domain, G-beta repeat CSD PF00313.22 CBZ24977.1 - 2.2e-10 40.2 0.4 1.4e-05 24.8 0.3 3.7 4 0 0 4 4 4 2 'Cold-shock' DNA-binding domain S1-like PF14444.6 CBZ24977.1 - 0.026 14.5 1.7 0.3 11.1 0.1 2.8 3 0 0 3 3 3 0 S1-like Tub PF01167.18 CBZ24978.1 - 5.4e-33 114.7 0.0 5e-31 108.3 0.0 2.6 2 1 0 2 2 2 2 Tub family Enolase_C PF00113.22 CBZ24980.1 - 9.6e-128 425.5 0.0 1.3e-127 425.1 0.0 1.1 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.16 CBZ24980.1 - 5.4e-58 194.8 0.1 9.5e-58 194.0 0.1 1.4 1 0 0 1 1 1 1 Enolase, N-terminal domain MR_MLE_C PF13378.6 CBZ24980.1 - 6e-08 32.5 0.0 1e-07 31.8 0.0 1.4 1 1 0 1 1 1 1 Enolase C-terminal domain-like MAAL_C PF07476.11 CBZ24980.1 - 0.00039 19.7 1.0 0.0005 19.3 0.1 1.5 2 0 0 2 2 2 1 Methylaspartate ammonia-lyase C-terminus FYVE PF01363.21 CBZ24981.1 - 4.8e-17 61.9 19.2 3e-16 59.3 13.6 3.3 2 1 0 2 2 2 1 FYVE zinc finger Ras PF00071.22 CBZ24981.1 - 4.9e-09 36.0 0.0 7.7e-09 35.3 0.0 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CBZ24981.1 - 2.9e-06 27.5 0.0 5.3e-06 26.6 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase F-box-like PF12937.7 CBZ24981.1 - 0.0011 18.8 0.1 0.0011 18.8 0.1 2.0 2 0 0 2 2 2 1 F-box-like zf-RING_9 PF13901.6 CBZ24981.1 - 0.021 14.8 0.4 0.021 14.8 0.4 2.0 2 0 0 2 2 2 0 Putative zinc-RING and/or ribbon Zf_RING PF16744.5 CBZ24981.1 - 0.023 14.8 4.8 0.12 12.5 1.0 2.7 2 0 0 2 2 2 0 KIAA1045 RING finger AAA_7 PF12775.7 CBZ24981.1 - 0.062 12.8 0.0 0.13 11.7 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region F-box PF00646.33 CBZ24981.1 - 0.11 12.4 1.7 0.14 12.1 0.1 2.0 2 0 0 2 2 2 0 F-box domain PAP_central PF04928.17 CBZ24982.1 - 5e-55 186.2 0.0 8.4e-55 185.4 0.0 1.2 1 0 0 1 1 1 1 Poly(A) polymerase central domain PAP_RNA-bind PF04926.15 CBZ24982.1 - 6.7e-34 117.0 0.0 1.3e-33 116.1 0.0 1.5 1 0 0 1 1 1 1 Poly(A) polymerase predicted RNA binding domain NTP_transf_2 PF01909.23 CBZ24982.1 - 1e-05 25.7 0.0 2.3e-05 24.6 0.0 1.5 1 0 0 1 1 1 1 Nucleotidyltransferase domain DNA_pol_B_palm PF14792.6 CBZ24982.1 - 0.02 15.1 0.0 0.048 13.9 0.0 1.6 1 0 0 1 1 1 0 DNA polymerase beta palm Glyco_hydro81C PF17652.1 CBZ24982.1 - 0.16 11.2 0.0 0.25 10.6 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 81 C-terminal domain SRP-alpha_N PF04086.13 CBZ24982.1 - 2.3 8.1 5.7 3.7 7.4 5.7 1.3 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal MGC-24 PF05283.11 CBZ24982.1 - 5.7 7.4 7.1 15 6.1 7.1 1.7 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin Carb_kinase PF01256.17 CBZ24983.1 - 1.6e-46 158.8 7.3 2.7e-46 158.0 7.3 1.4 1 0 0 1 1 1 1 Carbohydrate kinase YjeF_N PF03853.15 CBZ24983.1 - 3.4e-45 154.0 0.1 1.1e-44 152.3 0.0 1.9 2 0 0 2 2 2 1 YjeF-related protein N-terminus Prog_receptor PF02161.15 CBZ24983.1 - 0.0081 14.9 1.1 0.013 14.2 1.1 1.3 1 0 0 1 1 1 1 Progesterone receptor PSS PF03034.15 CBZ24984.1 - 7.4e-97 324.4 13.4 1.1e-96 323.8 13.4 1.2 1 0 0 1 1 1 1 Phosphatidyl serine synthase DUF4381 PF14316.6 CBZ24984.1 - 0.25 11.6 13.6 4 7.7 0.2 3.8 4 0 0 4 4 4 0 Domain of unknown function (DUF4381) NIF PF03031.18 CBZ24985.1 - 5.6e-14 52.2 0.0 6.9e-07 29.2 0.1 2.1 2 0 0 2 2 2 2 NLI interacting factor-like phosphatase DUF4795 PF16043.5 CBZ24986.1 - 0.019 14.6 34.3 0.23 11.0 5.3 6.4 3 2 1 4 4 4 0 Domain of unknown function (DUF4795) DUF5039 PF16442.5 CBZ24986.1 - 0.093 12.3 0.5 0.22 11.1 0.5 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF5039) GPS2_interact PF15784.5 CBZ24986.1 - 0.28 11.6 5.0 0.99 9.9 0.1 3.5 3 0 0 3 3 3 0 G-protein pathway suppressor 2-interacting domain DASH_Duo1 PF08651.10 CBZ24986.1 - 0.33 10.8 3.5 42 4.0 0.0 4.4 5 0 0 5 5 5 0 DASH complex subunit Duo1 Spc7 PF08317.11 CBZ24986.1 - 1.1 8.1 34.2 0.85 8.4 3.5 4.8 3 2 2 5 5 5 0 Spc7 kinetochore protein DALR_2 PF09190.11 CBZ24986.1 - 2.8 8.5 7.7 6.1 7.4 0.6 4.1 3 0 0 3 3 3 0 DALR domain DUF1635 PF07795.11 CBZ24986.1 - 4 7.2 8.1 1.2 8.9 2.9 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1635) Golgin_A5 PF09787.9 CBZ24986.1 - 5.3 6.4 29.5 10 5.5 4.0 4.1 3 1 1 4 4 4 0 Golgin subfamily A member 5 DUF1515 PF07439.11 CBZ24986.1 - 8.3 6.5 9.9 1.7 8.7 1.4 3.9 2 2 1 3 3 3 0 Protein of unknown function (DUF1515) Med9 PF07544.13 CBZ24986.1 - 8.6 6.5 16.0 1.8 8.7 0.7 5.1 5 0 0 5 5 5 0 RNA polymerase II transcription mediator complex subunit 9 TMF_TATA_bd PF12325.8 CBZ24986.1 - 8.7 6.6 36.4 0.14 12.3 4.1 6.3 2 1 4 7 7 7 0 TATA element modulatory factor 1 TATA binding CHDCT2 PF08074.11 CBZ24986.1 - 8.8 6.5 14.5 0.057 13.6 1.2 3.8 3 1 1 4 4 4 0 CHDCT2 (NUC038) domain HTH_1 PF00126.27 CBZ24987.1 - 0.24 11.4 0.1 0.24 11.4 0.1 3.1 3 0 0 3 3 3 0 Bacterial regulatory helix-turn-helix protein, lysR family HTH_37 PF13744.6 CBZ24988.1 - 0.14 12.1 0.6 0.24 11.4 0.1 1.6 2 0 0 2 2 2 0 Helix-turn-helix domain Ribosomal_S27 PF01599.19 CBZ24991.1 - 5.3e-23 80.9 4.0 9.4e-23 80.1 4.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S27a ubiquitin PF00240.23 CBZ24991.1 - 6.6e-09 35.4 0.0 4e-08 32.9 0.0 2.2 2 1 0 2 2 2 1 Ubiquitin family Rad60-SLD PF11976.8 CBZ24991.1 - 8.4e-06 25.5 0.1 9.8e-05 22.1 0.0 2.4 2 1 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like IBR PF01485.21 CBZ24991.1 - 0.0045 17.2 0.7 0.0078 16.4 0.7 1.4 1 0 0 1 1 1 1 IBR domain, a half RING-finger domain F420_oxidored PF03807.17 CBZ24992.1 - 6.5e-07 29.8 0.0 2.3e-06 28.1 0.0 1.9 1 1 1 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent PDH PF02153.17 CBZ24992.1 - 0.046 12.7 0.0 0.076 12.0 0.0 1.2 1 0 0 1 1 1 0 Prephenate dehydrogenase Pkinase PF00069.25 CBZ24994.1 - 5.8e-64 216.0 0.0 1.5e-56 191.7 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ24994.1 - 4.7e-35 121.1 0.0 8.1e-33 113.8 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 CBZ24994.1 - 9.2e-05 21.4 0.0 9.2e-05 21.4 0.0 2.3 2 1 0 2 2 2 1 Fungal protein kinase APH PF01636.23 CBZ24994.1 - 0.02 14.8 0.1 0.29 11.0 0.2 2.0 1 1 1 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.14 CBZ24994.1 - 0.1 12.0 0.0 0.19 11.0 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 CBZ24994.1 - 0.17 11.2 0.0 0.28 10.4 0.0 1.2 1 0 0 1 1 1 0 Kinase-like SHMT PF00464.19 CBZ24997.1 - 8.6e-173 574.5 0.0 1e-172 574.3 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase DUF2529 PF10740.9 CBZ24997.1 - 0.091 12.4 0.0 0.17 11.5 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF2529) DnaJ PF00226.31 CBZ24998.1 - 2e-19 69.5 3.1 2e-19 69.5 3.1 2.0 2 0 0 2 2 1 1 DnaJ domain TPR_19 PF14559.6 CBZ24998.1 - 1.1e-10 41.8 23.7 0.01 16.4 3.2 6.0 4 3 2 6 6 6 4 Tetratricopeptide repeat TPR_12 PF13424.6 CBZ24998.1 - 0.00012 22.3 13.8 0.0027 18.0 2.3 4.0 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.6 CBZ24998.1 - 0.00067 19.7 2.9 0.73 10.2 0.0 3.9 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.28 CBZ24998.1 - 0.00075 19.2 3.7 0.73 9.8 0.9 3.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 CBZ24998.1 - 0.0038 17.2 12.7 0.66 10.2 2.0 5.2 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_6 PF13174.6 CBZ24998.1 - 0.026 15.2 11.9 19 6.2 0.1 6.7 7 0 0 7 7 7 0 Tetratricopeptide repeat Mhr1 PF12829.7 CBZ24998.1 - 0.045 13.8 1.3 7.8 6.7 0.1 3.2 3 0 0 3 3 3 0 Transcriptional regulation of mitochondrial recombination Fis1_TPR_C PF14853.6 CBZ24998.1 - 0.073 13.2 1.7 1.3 9.1 0.1 2.9 2 1 0 2 2 2 0 Fis1 C-terminal tetratricopeptide repeat TPR_17 PF13431.6 CBZ24998.1 - 0.096 13.1 4.0 20 5.8 0.0 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF884 PF05959.11 CBZ24998.1 - 0.099 12.3 0.1 0.19 11.4 0.1 1.4 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF884) TPR_9 PF13371.6 CBZ24998.1 - 0.1 12.8 14.8 0.96 9.6 0.3 4.4 3 1 1 4 4 4 0 Tetratricopeptide repeat Turandot PF07240.11 CBZ24998.1 - 0.12 12.3 0.2 0.62 10.1 0.0 2.3 2 0 0 2 2 2 0 Stress-inducible humoral factor Turandot Alkyl_sulf_dimr PF14863.6 CBZ24998.1 - 0.2 12.1 3.7 6.7 7.2 0.3 2.8 1 1 1 2 2 2 0 Alkyl sulfatase dimerisation TPR_14 PF13428.6 CBZ24998.1 - 0.24 12.3 26.8 3.6 8.6 0.1 7.6 5 3 5 10 10 9 0 Tetratricopeptide repeat TPR_16 PF13432.6 CBZ24998.1 - 2.6 8.8 22.3 0.2 12.3 0.8 4.0 5 1 0 5 5 3 0 Tetratricopeptide repeat GRP PF07172.11 CBZ24998.1 - 3.7 8.3 7.4 8.1 7.2 7.4 1.5 1 0 0 1 1 1 0 Glycine rich protein family FA_desaturase PF00487.24 CBZ24999.1 - 2.3e-34 119.4 12.2 2.3e-34 119.4 12.2 1.5 1 1 1 2 2 2 1 Fatty acid desaturase Cyt-b5 PF00173.28 CBZ24999.1 - 0.0061 16.7 0.0 0.014 15.5 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain DLIC PF05783.11 CBZ25000.1 - 0.1 11.4 0.1 0.47 9.2 0.3 2.0 2 1 0 2 2 2 0 Dynein light intermediate chain (DLIC) MMR_HSR1 PF01926.23 CBZ25000.1 - 0.1 12.7 0.0 11 6.2 0.0 2.5 2 0 0 2 2 2 0 50S ribosome-binding GTPase NAD_binding_5 PF07994.12 CBZ25002.1 - 2.3e-138 461.0 0.0 2.6e-138 460.8 0.0 1.0 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase Inos-1-P_synth PF01658.17 CBZ25002.1 - 8.7e-44 148.2 0.0 1.5e-43 147.5 0.0 1.4 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase tRNA-synt_1b PF00579.25 CBZ25003.1 - 1.3e-53 182.2 0.0 3.5e-48 164.4 0.0 2.6 2 1 0 2 2 2 2 tRNA synthetases class I (W and Y) EMP24_GP25L PF01105.24 CBZ25005.1 - 9.7e-21 74.5 0.0 1.2e-20 74.2 0.0 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Pkinase PF00069.25 CBZ25007.1 - 6.2e-65 219.2 0.0 7.7e-65 218.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ25007.1 - 2.2e-44 151.7 0.0 2.9e-44 151.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CBZ25007.1 - 1.9e-06 27.4 0.2 2.3e-05 23.9 0.0 2.1 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 CBZ25007.1 - 0.00025 19.9 0.0 0.00046 19.1 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 CBZ25007.1 - 0.022 14.7 0.7 0.5 10.2 0.0 2.4 2 0 0 2 2 2 0 Phosphotransferase enzyme family WD40 PF00400.32 CBZ25009.1 - 2.4e-07 31.3 17.0 0.12 13.3 0.1 9.0 10 0 0 10 10 10 3 WD domain, G-beta repeat AKNA PF12443.8 CBZ25009.1 - 0.041 14.5 0.4 0.23 12.2 0.4 2.3 1 0 0 1 1 1 0 AT-hook-containing transcription factor MetOD2 PF18548.1 CBZ25009.1 - 3.2 7.9 8.8 1.1 9.4 0.6 3.4 3 0 0 3 3 3 0 Metanogen output domain 2 C2 PF00168.30 CBZ25010.1 - 3.3e-05 24.1 0.0 0.15 12.4 0.0 2.5 2 0 0 2 2 2 2 C2 domain Vac14_Fig4_bd PF11916.8 CBZ25011.1 - 8.2e-47 159.2 1.8 8.2e-47 159.2 1.8 1.7 2 0 0 2 2 2 1 Vacuolar protein 14 C-terminal Fig4p binding Vac14_Fab1_bd PF12755.7 CBZ25011.1 - 2.1e-08 34.6 0.0 5.1e-07 30.2 0.0 2.5 2 0 0 2 2 2 1 Vacuolar 14 Fab1-binding region HEAT PF02985.22 CBZ25011.1 - 0.024 14.9 7.4 0.12 12.7 0.0 4.4 4 0 0 4 4 4 0 HEAT repeat TetR_C_30 PF17939.1 CBZ25011.1 - 0.039 14.2 0.2 0.16 12.2 0.2 2.1 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain MPC PF03650.13 CBZ25012.1 - 4e-14 52.7 0.1 4.9e-14 52.4 0.1 1.2 1 0 0 1 1 1 1 Mitochondrial pyruvate carriers GST_N_3 PF13417.6 CBZ25014.1 - 2.3e-07 31.1 0.0 4.4e-07 30.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Glutaredoxin PF00462.24 CBZ25014.1 - 2.9e-07 30.6 0.5 7.3e-07 29.3 0.3 1.8 1 1 1 2 2 2 1 Glutaredoxin GST_N_4 PF17172.4 CBZ25014.1 - 0.0068 17.1 0.1 0.024 15.4 0.0 2.0 3 0 0 3 3 3 1 Glutathione S-transferase N-terminal domain GST_N_2 PF13409.6 CBZ25014.1 - 0.071 13.4 0.0 0.17 12.2 0.0 1.7 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain TerY_C PF15616.6 CBZ25014.1 - 0.17 12.0 0.1 0.45 10.6 0.1 1.6 1 1 0 1 1 1 0 TerY-C metal binding domain Syja_N PF02383.18 CBZ25015.1 - 4.6e-25 88.6 0.0 6.8e-25 88.0 0.0 1.2 1 0 0 1 1 1 1 SacI homology domain CENP-T_C PF15511.6 CBZ25016.1 - 6.5e-07 29.4 0.1 8.9e-07 29.0 0.1 1.3 1 1 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold TAF PF02969.17 CBZ25016.1 - 0.00022 21.3 0.1 0.00037 20.6 0.1 1.3 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) Bromo_TP PF07524.13 CBZ25016.1 - 0.00049 20.0 0.0 0.00067 19.6 0.0 1.2 1 0 0 1 1 1 1 Bromodomain associated CBFD_NFYB_HMF PF00808.23 CBZ25016.1 - 0.00059 20.1 0.9 0.00063 20.0 0.1 1.4 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 CBZ25016.1 - 0.001 19.4 1.9 0.0019 18.5 1.9 1.5 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID-31kDa PF02291.15 CBZ25016.1 - 0.006 16.7 0.0 0.0078 16.3 0.0 1.1 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit Ribosomal_S17e PF00833.18 CBZ25016.1 - 0.052 13.5 0.6 0.061 13.3 0.6 1.2 1 0 0 1 1 1 0 Ribosomal S17 PCP_red PF08369.10 CBZ25016.1 - 0.075 13.3 0.7 0.34 11.2 0.1 2.3 2 0 0 2 2 2 0 Proto-chlorophyllide reductase 57 kD subunit GDA1_CD39 PF01150.17 CBZ25018.1 - 5e-81 272.5 0.0 6.6e-81 272.1 0.0 1.1 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family Ppx-GppA PF02541.16 CBZ25018.1 - 0.00056 19.4 0.0 0.00083 18.9 0.0 1.2 1 0 0 1 1 1 1 Ppx/GppA phosphatase family Lysine_decarbox PF03641.14 CBZ25019.1 - 3.5e-24 85.4 0.0 6.9e-24 84.4 0.0 1.5 1 0 0 1 1 1 1 Possible lysine decarboxylase LDcluster4 PF18306.1 CBZ25019.1 - 5.8e-08 32.5 0.0 1.1e-07 31.5 0.0 1.5 1 0 0 1 1 1 1 SLOG cluster4 family MSP1b PF03429.13 CBZ25019.1 - 0.0099 14.0 0.0 0.013 13.6 0.0 1.1 1 0 0 1 1 1 1 Major surface protein 1B DUF5601 PF18151.1 CBZ25019.1 - 0.11 12.8 0.1 5.6 7.4 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF5601) NAD_binding_1 PF00175.21 CBZ25020.1 - 2.1e-28 99.1 0.0 3.4e-28 98.4 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 CBZ25020.1 - 2e-25 89.0 0.0 3e-25 88.4 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.12 CBZ25020.1 - 4.3e-07 30.2 0.0 3.7e-05 23.9 0.0 2.2 2 0 0 2 2 2 2 Ferric reductase NAD binding domain MIF4G PF02854.19 CBZ25021.1 - 3e-24 85.8 1.7 5.5e-24 85.0 1.7 1.5 1 0 0 1 1 1 1 MIF4G domain CRM1_C PF08767.11 CBZ25021.1 - 0.0016 17.7 0.1 0.0056 15.9 0.0 1.9 2 0 0 2 2 2 1 CRM1 C terminal IMS PF00817.20 CBZ25021.1 - 0.059 13.4 0.1 0.64 10.0 0.1 2.4 1 1 0 1 1 1 0 impB/mucB/samB family RNA12 PF10443.9 CBZ25022.1 - 0.069 11.9 0.1 1.1 8.0 0.0 2.4 2 1 1 3 3 3 0 RNA12 protein OmpA_like PF16961.5 CBZ25022.1 - 0.24 11.0 0.0 0.37 10.4 0.0 1.2 1 0 0 1 1 1 0 Putative OmpA-OmpF-like porin family E_Pc_C PF06752.12 CBZ25022.1 - 1.4 9.0 6.6 1.1 9.3 4.1 2.0 2 0 0 2 2 2 0 Enhancer of Polycomb C-terminus EF-hand_like PF09279.11 CBZ25023.1 - 0.075 13.5 4.3 10 6.7 0.3 3.9 3 1 2 5 5 5 0 Phosphoinositide-specific phospholipase C, efhand-like AAA_2 PF07724.14 CBZ25024.1 - 9e-40 136.6 1.6 3.3e-31 108.7 0.7 2.8 1 1 1 2 2 2 2 AAA domain (Cdc48 subfamily) AAA PF00004.29 CBZ25024.1 - 1.3e-13 51.6 0.0 6.3e-06 26.6 0.0 3.0 2 1 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 CBZ25024.1 - 7e-09 35.8 0.4 1.9e-05 24.7 0.0 2.5 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 CBZ25024.1 - 6.2e-06 26.5 0.0 0.00029 21.1 0.0 2.4 2 0 0 2 2 2 1 AAA domain MCM PF00493.23 CBZ25024.1 - 1.5e-05 24.3 0.1 0.0019 17.3 0.0 2.4 2 0 0 2 2 2 1 MCM P-loop domain TniB PF05621.11 CBZ25024.1 - 3.3e-05 23.4 0.2 0.0029 17.0 0.0 2.3 2 0 0 2 2 2 1 Bacterial TniB protein ClpB_D2-small PF10431.9 CBZ25024.1 - 5.4e-05 23.2 0.4 0.00035 20.6 0.0 2.4 2 0 0 2 2 2 1 C-terminal, D2-small domain, of ClpB protein AAA_18 PF13238.6 CBZ25024.1 - 6.4e-05 23.5 0.2 0.00021 21.8 0.0 1.9 2 0 0 2 2 1 1 AAA domain Mg_chelatase PF01078.21 CBZ25024.1 - 8.8e-05 22.0 0.1 0.0021 17.5 0.0 2.8 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI AAA_16 PF13191.6 CBZ25024.1 - 0.0002 21.8 0.3 0.00062 20.2 0.3 1.7 1 1 0 1 1 1 1 AAA ATPase domain TIP49 PF06068.13 CBZ25024.1 - 0.00063 19.0 0.8 0.0011 18.3 0.0 1.7 2 1 0 2 2 2 1 TIP49 P-loop domain NTPase_1 PF03266.15 CBZ25024.1 - 0.00095 19.1 0.9 0.63 9.9 0.0 2.6 2 0 0 2 2 2 2 NTPase RuvB_N PF05496.12 CBZ25024.1 - 0.0015 18.3 0.1 0.013 15.2 0.0 2.4 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain DEAD PF00270.29 CBZ25024.1 - 0.0015 18.3 0.1 1.1 9.0 0.0 2.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_14 PF13173.6 CBZ25024.1 - 0.0054 16.8 0.1 2.9 7.9 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_24 PF13479.6 CBZ25024.1 - 0.0065 16.2 0.6 0.32 10.7 0.1 2.5 2 1 0 2 2 2 1 AAA domain AAA_33 PF13671.6 CBZ25024.1 - 0.0071 16.5 0.0 0.023 14.9 0.0 1.9 2 0 0 2 2 1 1 AAA domain TsaE PF02367.17 CBZ25024.1 - 0.012 15.6 0.0 0.035 14.1 0.0 1.8 2 0 0 2 2 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_28 PF13521.6 CBZ25024.1 - 0.017 15.4 0.1 0.13 12.5 0.0 2.4 2 1 1 3 3 3 0 AAA domain Sigma54_activat PF00158.26 CBZ25024.1 - 0.018 14.8 0.0 0.058 13.1 0.0 1.8 2 0 0 2 2 1 0 Sigma-54 interaction domain Zeta_toxin PF06414.12 CBZ25024.1 - 0.019 14.3 0.0 0.058 12.7 0.0 1.9 1 1 0 1 1 1 0 Zeta toxin AAA_19 PF13245.6 CBZ25024.1 - 0.026 14.8 0.7 0.09 13.1 0.7 1.9 1 1 0 1 1 1 0 AAA domain CPT PF07931.12 CBZ25024.1 - 0.031 14.1 0.2 0.26 11.1 0.0 2.5 3 0 0 3 3 3 0 Chloramphenicol phosphotransferase-like protein IstB_IS21 PF01695.17 CBZ25024.1 - 0.041 13.6 0.0 0.12 12.1 0.0 1.7 1 0 0 1 1 1 0 IstB-like ATP binding protein RsgA_GTPase PF03193.16 CBZ25024.1 - 0.042 13.8 0.0 0.091 12.7 0.0 1.6 1 0 0 1 1 1 0 RsgA GTPase AAA_7 PF12775.7 CBZ25024.1 - 0.043 13.3 0.0 0.074 12.6 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region NACHT PF05729.12 CBZ25024.1 - 0.043 13.7 0.1 3 7.8 0.0 2.7 2 1 0 2 2 2 0 NACHT domain ABC_tran PF00005.27 CBZ25024.1 - 0.051 14.1 0.1 0.12 12.9 0.1 1.6 1 0 0 1 1 1 0 ABC transporter RNA_helicase PF00910.22 CBZ25024.1 - 0.13 12.7 0.0 0.87 10.0 0.0 2.3 2 1 0 2 2 2 0 RNA helicase AAA_17 PF13207.6 CBZ25024.1 - 2.6 8.5 5.8 4.1 7.8 0.2 3.7 3 1 1 4 4 4 0 AAA domain FMO-like PF00743.19 CBZ25025.1 - 4.7e-27 94.6 0.1 1.8e-22 79.5 0.1 2.2 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 CBZ25025.1 - 3.4e-13 49.5 0.0 1.4e-12 47.5 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 CBZ25025.1 - 4.2e-10 39.4 0.6 2.7e-05 23.6 0.1 3.2 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 CBZ25025.1 - 2.6e-08 33.4 0.3 4.3e-06 26.1 0.2 2.3 2 0 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 CBZ25025.1 - 2.1e-05 24.7 0.0 8.2e-05 22.8 0.0 2.2 1 1 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 CBZ25025.1 - 0.00097 19.7 0.1 1.5 9.5 0.1 3.2 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase DUF1490 PF07371.12 CBZ25025.1 - 0.0023 18.0 1.4 0.0074 16.4 0.2 2.5 3 0 0 3 3 3 1 Protein of unknown function (DUF1490) NAD_binding_9 PF13454.6 CBZ25025.1 - 0.01 15.8 0.2 0.15 12.0 0.2 2.6 1 1 0 1 1 1 0 FAD-NAD(P)-binding IlvN PF07991.12 CBZ25025.1 - 0.012 15.2 0.0 0.88 9.1 0.0 2.5 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain AlaDh_PNT_C PF01262.21 CBZ25025.1 - 0.015 14.6 0.1 5.6 6.2 0.0 2.3 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain HI0933_like PF03486.14 CBZ25025.1 - 0.027 13.2 0.1 0.041 12.6 0.1 1.2 1 0 0 1 1 1 0 HI0933-like protein GIDA PF01134.22 CBZ25025.1 - 0.067 12.3 0.3 0.59 9.2 0.0 2.3 3 0 0 3 3 3 0 Glucose inhibited division protein A FAD_binding_2 PF00890.24 CBZ25025.1 - 0.07 12.2 1.7 0.29 10.1 1.5 2.3 1 1 0 1 1 1 0 FAD binding domain FAD_binding_3 PF01494.19 CBZ25025.1 - 0.083 12.1 0.1 0.17 11.1 0.1 1.4 1 0 0 1 1 1 0 FAD binding domain Mito_carr PF00153.27 CBZ25027.1 - 7.9e-43 144.3 0.8 3.1e-15 55.9 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein DEAD PF00270.29 CBZ25028.1 - 4.6e-41 140.5 0.1 9.1e-41 139.5 0.1 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CBZ25028.1 - 8e-27 93.8 6.6 6.3e-25 87.7 0.1 4.2 3 1 1 4 4 4 1 Helicase conserved C-terminal domain zf-CCCH PF00642.24 CBZ25029.1 - 8.5e-05 22.4 6.4 8.5e-05 22.4 6.4 2.3 2 0 0 2 2 2 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) oligo_HPY PF08352.12 CBZ25029.1 - 2.2 8.8 11.5 0.43 11.1 1.2 2.7 2 1 0 2 2 2 0 Oligopeptide/dipeptide transporter, C-terminal region zf-CCCH_4 PF18044.1 CBZ25031.1 - 7.2e-05 22.5 1.8 0.00011 21.8 1.8 1.3 1 0 0 1 1 1 1 CCCH-type zinc finger zf-CCCH PF00642.24 CBZ25031.1 - 0.00016 21.5 4.1 0.00028 20.7 4.1 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 CBZ25031.1 - 0.073 13.1 2.0 0.13 12.3 2.0 1.5 1 0 0 1 1 1 0 Zinc finger domain zf-CCCH_2 PF14608.6 CBZ25031.1 - 0.41 11.2 2.7 0.79 10.3 2.7 1.5 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger PP2C PF00481.21 CBZ25032.1 - 2.7e-64 217.3 0.0 5.1e-64 216.4 0.0 1.4 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 CBZ25032.1 - 0.0054 16.4 0.0 0.016 14.9 0.0 1.7 1 1 0 1 1 1 1 Protein phosphatase 2C Gly_acyl_tr_N PF06021.11 CBZ25032.1 - 0.063 13.4 0.3 0.1 12.7 0.3 1.2 1 0 0 1 1 1 0 Aralkyl acyl-CoA:amino acid N-acyltransferase Pkinase PF00069.25 CBZ25033.1 - 8.8e-44 149.8 0.0 1.3e-43 149.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ25033.1 - 3.2e-14 52.9 0.0 7.6e-14 51.6 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.23 CBZ25033.1 - 0.00012 22.1 0.2 0.0025 17.8 0.0 2.5 2 1 0 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 CBZ25033.1 - 0.004 16.8 0.0 0.0066 16.1 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase Pox_ser-thr_kin PF05445.11 CBZ25033.1 - 0.22 10.5 0.1 0.35 9.8 0.1 1.3 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Cyt-b5 PF00173.28 CBZ25035.1 - 2.4e-07 30.8 0.0 3.9e-07 30.1 0.0 1.4 1 1 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Adeno_E3_CR2 PF02439.15 CBZ25035.1 - 0.13 12.1 0.0 0.21 11.4 0.0 1.3 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Pkr1 PF08636.10 CBZ25036.1 - 0.38 10.9 3.2 0.52 10.5 2.2 1.8 2 0 0 2 2 2 0 ER protein Pkr1 Ribosomal_L13 PF00572.18 CBZ25037.1 - 8.9e-06 26.0 3.7 0.00036 20.8 0.1 2.6 2 1 1 3 3 3 2 Ribosomal protein L13 DUF4455 PF14643.6 CBZ25037.1 - 0.031 13.0 0.8 0.043 12.5 0.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4455) Metallophos PF00149.28 CBZ25039.1 - 4.1e-31 109.1 0.0 5.2e-31 108.7 0.0 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 CBZ25039.1 - 0.033 14.6 0.8 0.11 13.0 0.3 2.0 2 0 0 2 2 2 0 Serine-threonine protein phosphatase N-terminal domain WD40 PF00400.32 CBZ25041.1 - 1.2e-08 35.4 5.7 0.0067 17.3 0.0 5.0 5 1 0 5 5 5 3 WD domain, G-beta repeat MYEOV2 PF15004.6 CBZ25041.1 - 0.1 13.0 0.0 0.32 11.5 0.0 1.8 1 0 0 1 1 1 0 Myeloma-overexpressed-like tRNA-synt_2 PF00152.20 CBZ25042.1 - 1.9e-74 250.6 0.0 3.3e-74 249.8 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 CBZ25042.1 - 3.1e-13 49.5 0.0 6.1e-13 48.6 0.0 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 CBZ25042.1 - 2.5e-06 27.1 0.0 0.022 14.3 0.0 2.7 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) tRNA_anti_2 PF13742.6 CBZ25042.1 - 0.013 15.6 0.0 0.023 14.9 0.0 1.4 1 0 0 1 1 1 0 OB-fold nucleic acid binding domain Ubiquitin_5 PF18037.1 CBZ25042.1 - 0.1 12.9 0.1 0.31 11.4 0.1 1.8 1 0 0 1 1 1 0 Ubiquitin-like domain FlxA PF14282.6 CBZ25042.1 - 0.1 12.6 0.7 0.22 11.5 0.7 1.4 1 0 0 1 1 1 0 FlxA-like protein EF-hand_14 PF17959.1 CBZ25042.1 - 0.12 12.7 0.1 0.36 11.2 0.1 1.8 1 0 0 1 1 1 0 EF-hand domain Peroxin-13_N PF04088.13 CBZ25045.1 - 0.071 13.4 1.0 0.12 12.7 0.5 1.7 2 0 0 2 2 2 0 Peroxin 13, N-terminal region MAJIN PF15077.6 CBZ25045.1 - 3.6 7.3 7.5 6.5 6.5 7.5 1.4 1 0 0 1 1 1 0 Membrane-anchored junction protein Rtt102p PF09510.10 CBZ25045.1 - 5.3 7.3 7.9 1.6 9.0 2.8 2.1 2 0 0 2 2 2 0 Rtt102p-like transcription regulator protein RPA_C PF08784.11 CBZ25046.1 - 1.4e-12 48.2 0.9 4.5e-12 46.6 0.5 2.1 2 0 0 2 2 2 1 Replication protein A C terminal tRNA_anti-codon PF01336.25 CBZ25046.1 - 7.2e-09 35.5 0.1 1.3e-08 34.7 0.1 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain GntR PF00392.21 CBZ25046.1 - 0.098 12.3 0.0 0.23 11.1 0.0 1.7 1 0 0 1 1 1 0 Bacterial regulatory proteins, gntR family PaaX PF07848.12 CBZ25046.1 - 0.13 12.5 0.0 0.3 11.4 0.0 1.5 1 0 0 1 1 1 0 PaaX-like protein PPR_2 PF13041.6 CBZ25047.1 - 2.7e-07 30.7 0.2 0.023 14.9 0.0 2.3 2 0 0 2 2 2 2 PPR repeat family PPR_long PF17177.4 CBZ25047.1 - 0.0023 17.3 0.0 0.24 10.7 0.0 2.1 1 1 1 2 2 2 2 Pentacotripeptide-repeat region of PRORP PPR_3 PF13812.6 CBZ25047.1 - 0.0062 16.6 0.1 0.26 11.4 0.0 2.2 2 0 0 2 2 2 1 Pentatricopeptide repeat domain Prefoldin_2 PF01920.20 CBZ25047.1 - 0.036 14.0 0.0 0.079 12.9 0.0 1.5 1 0 0 1 1 1 0 Prefoldin subunit FERM_f0 PF16511.5 CBZ25047.1 - 0.039 14.2 0.0 0.079 13.3 0.0 1.5 1 0 0 1 1 1 0 N-terminal or F0 domain of Talin-head FERM RPM2 PF08579.11 CBZ25047.1 - 0.053 13.9 0.0 0.077 13.4 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial ribonuclease P subunit (RPM2) PPR_2 PF13041.6 CBZ25048.1 - 2.7e-07 30.7 0.2 0.023 14.9 0.0 2.3 2 0 0 2 2 2 2 PPR repeat family PPR_long PF17177.4 CBZ25048.1 - 0.0023 17.3 0.0 0.24 10.7 0.0 2.1 1 1 1 2 2 2 2 Pentacotripeptide-repeat region of PRORP PPR_3 PF13812.6 CBZ25048.1 - 0.0062 16.6 0.1 0.26 11.4 0.0 2.2 2 0 0 2 2 2 1 Pentatricopeptide repeat domain Prefoldin_2 PF01920.20 CBZ25048.1 - 0.036 14.0 0.0 0.079 12.9 0.0 1.5 1 0 0 1 1 1 0 Prefoldin subunit FERM_f0 PF16511.5 CBZ25048.1 - 0.039 14.2 0.0 0.079 13.3 0.0 1.5 1 0 0 1 1 1 0 N-terminal or F0 domain of Talin-head FERM RPM2 PF08579.11 CBZ25048.1 - 0.053 13.9 0.0 0.077 13.4 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial ribonuclease P subunit (RPM2) DUF3081 PF11280.8 CBZ25049.1 - 0.15 11.9 0.0 1.3 8.9 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3081) Ecotin PF03974.13 CBZ25050.1 - 9.2e-38 129.0 0.0 1.1e-37 128.8 0.0 1.0 1 0 0 1 1 1 1 Ecotin IATP PF04568.12 CBZ25051.1 - 0.15 12.5 1.4 0.55 10.7 1.4 2.0 1 0 0 1 1 1 0 Mitochondrial ATPase inhibitor, IATP Abhydrolase_3 PF07859.13 CBZ25052.1 - 6.9e-12 45.7 0.1 2e-11 44.1 0.0 1.8 2 0 0 2 2 2 1 alpha/beta hydrolase fold COesterase PF00135.28 CBZ25052.1 - 6.8e-10 38.4 0.2 2.1e-09 36.8 0.0 1.9 1 1 1 2 2 2 1 Carboxylesterase family Abhydrolase_6 PF12697.7 CBZ25052.1 - 9.8e-06 26.3 1.8 2.2e-05 25.2 0.0 2.3 3 0 0 3 3 3 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 CBZ25052.1 - 5.1e-05 22.8 1.3 0.059 12.8 0.1 3.0 3 1 0 3 3 3 2 Prolyl oligopeptidase family DUF4566 PF15130.6 CBZ25052.1 - 0.041 13.3 0.1 0.17 11.2 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4566) Abhydrolase_1 PF00561.20 CBZ25052.1 - 0.087 12.5 0.0 0.19 11.3 0.0 1.6 1 0 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_3 PF07859.13 CBZ25053.1 - 6.4e-11 42.5 0.0 1.4e-10 41.4 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 CBZ25053.1 - 1e-08 34.5 0.0 1.7e-08 33.9 0.0 1.3 1 0 0 1 1 1 1 Carboxylesterase family Peptidase_S9 PF00326.21 CBZ25053.1 - 1.6e-05 24.5 0.1 0.065 12.7 0.1 2.8 2 1 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 CBZ25053.1 - 0.084 12.5 0.0 0.23 11.1 0.0 1.7 1 0 0 1 1 1 0 alpha/beta hydrolase fold MAJIN PF15077.6 CBZ25053.1 - 0.23 11.2 2.1 5.9 6.6 0.1 2.5 2 0 0 2 2 2 0 Membrane-anchored junction protein PseudoU_synth_2 PF00849.22 CBZ25056.1 - 1.8e-18 67.1 0.8 1.9e-08 34.6 0.2 3.3 3 0 0 3 3 3 3 RNA pseudouridylate synthase Viral_RdRp_C PF17501.2 CBZ25056.1 - 0.15 12.5 2.4 14 6.2 0.2 2.9 2 0 0 2 2 2 0 Viral RNA-directed RNA polymerase FAF PF11250.8 CBZ25056.1 - 0.21 11.8 3.1 2.1 8.7 0.2 3.1 2 0 0 2 2 2 0 Fantastic Four meristem regulator Ribosomal_60s PF00428.19 CBZ25057.1 - 1.6e-21 76.7 13.3 1.9e-21 76.4 13.3 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein Arg_repressor_C PF02863.18 CBZ25057.1 - 0.0076 16.1 0.5 0.0076 16.1 0.5 2.2 2 0 0 2 2 2 1 Arginine repressor, C-terminal domain 3HBOH PF10605.9 CBZ25057.1 - 0.029 12.6 5.0 0.031 12.5 5.0 1.0 1 0 0 1 1 1 0 3HB-oligomer hydrolase (3HBOH) Ribosomal_60s PF00428.19 CBZ25058.1 - 1.6e-21 76.7 13.3 1.9e-21 76.4 13.3 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein Arg_repressor_C PF02863.18 CBZ25058.1 - 0.0076 16.1 0.5 0.0076 16.1 0.5 2.2 2 0 0 2 2 2 1 Arginine repressor, C-terminal domain 3HBOH PF10605.9 CBZ25058.1 - 0.029 12.6 5.0 0.031 12.5 5.0 1.0 1 0 0 1 1 1 0 3HB-oligomer hydrolase (3HBOH) Asparaginase PF00710.20 CBZ25059.1 - 3e-52 177.0 0.0 4.5e-52 176.4 0.0 1.2 1 0 0 1 1 1 1 Asparaginase, N-terminal Asparaginase_C PF17763.1 CBZ25059.1 - 2.9e-21 75.8 0.0 4.8e-21 75.1 0.0 1.3 1 0 0 1 1 1 1 Glutaminase/Asparaginase C-terminal domain DUF282 PF03380.14 CBZ25059.1 - 0.1 12.6 1.2 16 5.5 0.0 3.1 3 0 0 3 3 3 0 Caenorhabditis protein of unknown function, DUF282 Zf_RING PF16744.5 CBZ25059.1 - 0.13 12.4 0.0 0.33 11.1 0.0 1.6 1 0 0 1 1 1 0 KIAA1045 RING finger PPR_2 PF13041.6 CBZ25061.1 - 0.0055 16.9 0.0 0.079 13.2 0.0 2.4 1 1 1 2 2 2 2 PPR repeat family GFO_IDH_MocA PF01408.22 CBZ25064.1 - 3.6e-13 50.4 27.7 58 4.5 0.0 15.4 8 3 6 15 15 15 1 Oxidoreductase family, NAD-binding Rossmann fold G6PD_N PF00479.22 CBZ25064.1 - 7.7e-08 33.2 22.3 78 3.8 0.1 12.9 6 4 7 15 15 15 0 Glucose-6-phosphate dehydrogenase, NAD binding domain LMP PF04778.12 CBZ25064.1 - 0.013 15.5 23.0 62 3.5 0.1 11.5 7 5 11 18 18 18 0 LMP repeated region EspB_PE PF18625.1 CBZ25065.1 - 0.0078 16.6 1.2 0.0078 16.6 1.2 3.1 3 0 0 3 3 3 1 ESX-1 secreted protein B PE domain DinB_2 PF12867.7 CBZ25065.1 - 0.054 14.0 1.8 0.36 11.3 0.1 2.8 2 0 0 2 2 2 0 DinB superfamily AAA PF00004.29 CBZ25066.1 - 1.2e-38 132.6 0.2 2.5e-38 131.5 0.0 1.7 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 CBZ25066.1 - 3.2e-12 46.0 0.1 7.4e-12 44.9 0.1 1.7 1 0 0 1 1 1 1 AAA+ lid domain Vps4_C PF09336.10 CBZ25066.1 - 4.1e-09 36.3 0.0 1.6e-08 34.4 0.0 2.0 1 0 0 1 1 1 1 Vps4 C terminal oligomerisation domain AAA_5 PF07728.14 CBZ25066.1 - 9.9e-06 25.6 0.3 7.5e-05 22.8 0.1 2.6 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 CBZ25066.1 - 1.7e-05 24.6 0.0 3.9e-05 23.5 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 CBZ25066.1 - 0.00012 22.3 0.2 0.0058 16.9 0.0 3.1 1 1 0 2 2 2 1 AAA domain AAA_16 PF13191.6 CBZ25066.1 - 0.0014 19.0 4.4 0.022 15.1 0.0 3.5 2 1 0 3 3 3 1 AAA ATPase domain AAA_2 PF07724.14 CBZ25066.1 - 0.0031 17.6 0.0 0.0053 16.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) TIP49 PF06068.13 CBZ25066.1 - 0.0035 16.6 0.0 0.006 15.8 0.0 1.3 1 0 0 1 1 1 1 TIP49 P-loop domain IstB_IS21 PF01695.17 CBZ25066.1 - 0.0057 16.4 0.0 0.011 15.5 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein Mg_chelatase PF01078.21 CBZ25066.1 - 0.0058 16.0 0.1 0.013 14.9 0.1 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_18 PF13238.6 CBZ25066.1 - 0.02 15.4 0.5 0.053 14.1 0.0 2.0 2 0 0 2 2 1 0 AAA domain TniB PF05621.11 CBZ25066.1 - 0.028 13.8 0.0 2.8 7.3 0.0 3.0 3 0 0 3 3 3 0 Bacterial TniB protein AAA_33 PF13671.6 CBZ25066.1 - 0.028 14.6 1.6 0.14 12.3 0.0 2.7 3 1 0 3 3 2 0 AAA domain AAA_25 PF13481.6 CBZ25066.1 - 0.045 13.3 0.2 0.59 9.7 0.0 2.4 1 1 1 2 2 2 0 AAA domain DUF815 PF05673.13 CBZ25066.1 - 0.05 12.8 0.0 0.11 11.7 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_14 PF13173.6 CBZ25066.1 - 0.064 13.3 0.0 0.12 12.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 CBZ25066.1 - 0.12 12.8 0.0 0.25 11.7 0.0 1.6 1 0 0 1 1 1 0 RNA helicase Parvo_NS1 PF01057.17 CBZ25066.1 - 0.13 11.3 0.0 0.21 10.7 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_24 PF13479.6 CBZ25066.1 - 0.22 11.2 0.0 0.38 10.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 CBZ25066.1 - 0.28 10.7 0.0 0.56 9.7 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region Ecotin PF03974.13 CBZ25068.1 - 4.4e-37 126.8 0.1 7.1e-37 126.1 0.1 1.3 1 0 0 1 1 1 1 Ecotin GDNF PF02351.16 CBZ25071.1 - 7.5 7.6 9.5 14 6.8 1.7 2.8 2 0 0 2 2 2 0 GDNF/GAS1 domain ATG16 PF08614.11 CBZ25072.1 - 0.42 10.8 33.0 3.5 7.8 11.5 4.2 3 1 1 4 4 4 0 Autophagy protein 16 (ATG16) Fez1 PF06818.15 CBZ25072.1 - 1.5 9.2 0.0 1.5 9.2 0.0 4.1 3 2 0 3 3 3 0 Fez1 CBP4 PF07960.11 CBZ25072.1 - 2.3 8.1 6.0 4.3 7.2 0.0 3.0 2 0 0 2 2 2 0 CBP4 SPC22 PF04573.12 CBZ25074.1 - 3e-15 56.1 0.1 3.7e-10 39.5 0.0 3.0 3 0 0 3 3 3 3 Signal peptidase subunit MDH PF02315.16 CBZ25075.1 - 0.017 15.2 0.2 0.034 14.2 0.2 1.4 1 0 0 1 1 1 0 Methanol dehydrogenase beta subunit FAM183 PF14886.6 CBZ25075.1 - 0.029 15.1 1.8 0.26 12.0 1.8 2.6 1 1 0 1 1 1 0 FAM183A and FAM183B related LLC1 PF14945.6 CBZ25075.1 - 0.037 14.6 0.6 6.7 7.3 0.0 2.3 2 0 0 2 2 2 0 Normal lung function maintenance, Low in Lung Cancer 1 protein Zein PF01559.16 CBZ25076.1 - 0.021 14.4 1.9 0.048 13.3 1.9 1.5 1 0 0 1 1 1 0 Zein seed storage protein Fez1 PF06818.15 CBZ25076.1 - 0.18 12.2 4.7 0.47 10.9 4.7 1.8 1 0 0 1 1 1 0 Fez1 Uso1_p115_C PF04871.13 CBZ25076.1 - 2.5 8.5 9.6 12 6.3 2.0 2.7 2 0 0 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region ChapFlgA_N PF17656.1 CBZ25077.1 - 1.1 9.4 2.8 2 8.7 0.0 2.8 3 0 0 3 3 3 0 FlgA N-terminal domain CRAL_TRIO PF00650.20 CBZ25078.1 - 1.9e-16 60.2 0.0 7.1e-15 55.1 0.0 2.7 2 1 0 2 2 2 1 CRAL/TRIO domain Strep_SA_rep PF06696.11 CBZ25078.1 - 0.14 12.2 0.7 1.4 9.0 0.1 2.6 2 0 0 2 2 2 0 Streptococcal surface antigen repeat DUF842 PF05811.13 CBZ25080.1 - 0.04 13.6 4.0 0.078 12.7 4.0 1.4 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF842) Osmo_CC PF08946.10 CBZ25080.1 - 0.66 10.3 4.2 1.6 9.0 4.2 1.6 1 0 0 1 1 1 0 Osmosensory transporter coiled coil Kelch_4 PF13418.6 CBZ25081.1 - 5.9e-22 77.4 2.3 3e-06 27.1 0.0 6.6 6 0 0 6 6 6 4 Galactose oxidase, central domain Kelch_5 PF13854.6 CBZ25081.1 - 1.9e-19 69.2 1.7 5.8e-05 23.0 0.0 5.4 5 0 0 5 5 5 4 Kelch motif Kelch_6 PF13964.6 CBZ25081.1 - 4e-15 55.5 0.9 4.5e-07 29.9 0.1 4.1 4 0 0 4 4 4 2 Kelch motif Kelch_2 PF07646.15 CBZ25081.1 - 2.6e-12 46.2 4.9 0.00023 21.0 0.0 4.7 5 0 0 5 5 5 3 Kelch motif Kelch_3 PF13415.6 CBZ25081.1 - 1.5e-11 44.3 13.1 0.00035 20.8 0.0 6.8 6 0 0 6 6 6 3 Galactose oxidase, central domain Kelch_1 PF01344.25 CBZ25081.1 - 2.2e-09 36.7 5.4 0.0066 16.0 0.1 4.0 3 0 0 3 3 3 3 Kelch motif Ipi1_N PF12333.8 CBZ25084.1 - 0.00069 20.2 5.2 0.027 15.1 0.2 3.9 3 1 1 4 4 4 2 Rix1 complex component involved in 60S ribosome maturation V-ATPase_H_C PF11698.8 CBZ25084.1 - 0.067 13.3 0.0 0.13 12.4 0.0 1.5 1 0 0 1 1 1 0 V-ATPase subunit H Arm PF00514.23 CBZ25084.1 - 0.15 12.1 2.5 2.2 8.4 0.4 2.9 2 0 0 2 2 2 0 Armadillo/beta-catenin-like repeat HEAT PF02985.22 CBZ25084.1 - 0.21 11.9 1.5 1.2 9.5 0.1 2.9 3 0 0 3 3 3 0 HEAT repeat Cmc1 PF08583.10 CBZ25085.1 - 0.0014 18.6 1.7 0.0014 18.6 1.7 2.0 2 0 0 2 2 2 1 Cytochrome c oxidase biogenesis protein Cmc1 like RseA_C PF03873.13 CBZ25085.1 - 0.015 15.5 0.2 0.048 13.9 0.0 1.9 2 0 0 2 2 2 0 Anti sigma-E protein RseA, C-terminal domain UPF0203 PF05254.12 CBZ25085.1 - 0.17 12.1 3.3 0.12 12.6 0.8 2.0 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0203) tRNA-synt_2c PF01411.19 CBZ25086.1 - 0.0053 15.3 0.0 0.0071 14.9 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (A) tRNA_SAD PF07973.14 CBZ25086.1 - 0.015 15.3 0.1 0.05 13.7 0.1 1.9 1 0 0 1 1 1 0 Threonyl and Alanyl tRNA synthetase second additional domain DAO PF01266.24 CBZ25089.1 - 0.0003 20.5 0.1 0.00076 19.2 0.0 1.7 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 CBZ25089.1 - 0.00046 19.5 2.5 0.47 9.6 0.3 3.6 2 1 1 3 3 3 2 FAD binding domain Pyr_redox PF00070.27 CBZ25089.1 - 0.0049 17.4 0.0 0.01 16.4 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 CBZ25089.1 - 0.012 14.9 0.0 0.019 14.2 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.16 CBZ25089.1 - 0.13 11.9 0.0 0.33 10.6 0.0 1.7 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA Methyltransf_16 PF10294.9 CBZ25090.1 - 2.9e-09 36.9 0.1 7.1e-06 25.9 0.0 2.1 2 0 0 2 2 2 2 Lysine methyltransferase Methyltransf_25 PF13649.6 CBZ25090.1 - 0.087 13.5 0.1 0.37 11.5 0.1 2.0 1 1 0 1 1 1 0 Methyltransferase domain PrmA PF06325.13 CBZ25090.1 - 0.1 12.0 0.0 0.15 11.4 0.0 1.1 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) VIR_N PF15912.5 CBZ25090.1 - 1.9 8.0 4.4 0.37 10.3 0.2 1.8 2 0 0 2 2 2 0 Virilizer, N-terminal DUF2871 PF11070.8 CBZ25091.1 - 2.1e-41 141.3 9.9 2.5e-41 141.1 9.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2871) TrbC PF04956.13 CBZ25091.1 - 0.12 12.6 2.3 0.3 11.3 2.3 1.7 1 1 0 1 1 1 0 TrbC/VIRB2 family DUF2684 PF10885.8 CBZ25091.1 - 1 9.5 4.2 3.5 7.8 1.3 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF2684) ABC_tran PF00005.27 CBZ25093.1 - 3.8e-54 182.9 0.0 4.3e-29 101.8 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC2_membrane_3 PF12698.7 CBZ25093.1 - 2.4e-41 142.0 65.0 2.1e-29 102.8 26.3 3.5 2 2 0 2 2 2 2 ABC-2 family transporter protein AAA_21 PF13304.6 CBZ25093.1 - 1.9e-20 73.9 2.1 6.9e-07 29.4 0.1 4.8 5 0 0 5 5 5 3 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 CBZ25093.1 - 2.2e-06 27.3 0.0 0.14 11.6 0.0 3.7 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 CBZ25093.1 - 8.6e-05 23.1 1.0 0.035 14.6 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.6 CBZ25093.1 - 0.00014 21.5 0.5 0.029 14.1 0.0 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain DUF4162 PF13732.6 CBZ25093.1 - 0.00083 20.0 0.0 0.87 10.3 0.0 3.0 3 0 0 3 3 3 1 Domain of unknown function (DUF4162) RsgA_GTPase PF03193.16 CBZ25093.1 - 0.0011 18.9 0.0 0.26 11.2 0.0 2.5 2 0 0 2 2 2 1 RsgA GTPase AAA_30 PF13604.6 CBZ25093.1 - 0.004 16.9 0.0 0.12 12.1 0.0 2.4 2 0 0 2 2 2 1 AAA domain Mg_chelatase PF01078.21 CBZ25093.1 - 0.044 13.2 0.3 3.5 6.9 0.0 3.5 4 0 0 4 4 4 0 Magnesium chelatase, subunit ChlI AAA_27 PF13514.6 CBZ25093.1 - 0.056 13.0 0.1 1.6 8.3 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_15 PF13175.6 CBZ25093.1 - 0.073 12.8 0.2 5.2 6.7 0.0 2.4 2 0 0 2 2 2 0 AAA ATPase domain PTPRCAP PF15713.5 CBZ25093.1 - 0.09 13.1 1.5 0.21 11.9 1.5 1.6 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated SbcCD_C PF13558.6 CBZ25093.1 - 0.14 12.4 0.0 8.8 6.6 0.0 3.4 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit Pkinase PF00069.25 CBZ25094.1 - 4.1e-28 98.5 0.0 5.7e-28 98.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ25094.1 - 9e-13 48.1 0.0 1.3e-12 47.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CBZ25094.1 - 0.00094 18.6 0.0 0.0013 18.1 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 CBZ25094.1 - 0.17 10.7 0.0 0.24 10.1 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase IL13 PF03487.13 CBZ25096.1 - 0.09 12.6 0.6 0.33 10.7 0.6 2.0 1 0 0 1 1 1 0 Interleukin-13 Pex16 PF08610.10 CBZ25097.1 - 4.7e-16 58.9 0.0 4.4e-13 49.1 0.0 2.5 2 0 0 2 2 2 2 Peroxisomal membrane protein (Pex16) DPM2 PF07297.12 CBZ25098.1 - 9.5e-18 64.3 1.3 1.3e-17 63.9 1.3 1.2 1 0 0 1 1 1 1 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) GDI PF00996.18 CBZ25099.1 - 1.2e-20 73.5 0.0 5.4e-11 41.7 0.0 2.7 2 1 0 2 2 2 2 GDP dissociation inhibitor Methyltransf_16 PF10294.9 CBZ25099.1 - 5.4e-12 45.8 0.0 2.3e-05 24.2 0.0 2.3 2 0 0 2 2 2 2 Lysine methyltransferase PrmA PF06325.13 CBZ25099.1 - 0.18 11.2 0.0 0.3 10.4 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Nuc_sug_transp PF04142.15 CBZ25102.1 - 2.3e-27 96.0 20.2 1.4e-25 90.2 20.2 2.7 1 1 0 1 1 1 1 Nucleotide-sugar transporter EamA PF00892.20 CBZ25102.1 - 2.5e-06 27.7 24.3 0.00058 20.0 1.1 3.8 3 1 1 4 4 4 2 EamA-like transporter family CAP_N PF01213.19 CBZ25103.1 - 0.46 9.9 1.6 0.44 10.0 0.1 1.7 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal MFS_1 PF07690.16 CBZ25105.1 - 4.7e-12 45.5 44.4 7.7e-08 31.6 10.6 3.9 2 2 2 4 4 4 4 Major Facilitator Superfamily Sugar_tr PF00083.24 CBZ25105.1 - 5.3e-08 32.2 2.1 5.3e-08 32.2 2.1 2.9 2 1 0 3 3 3 2 Sugar (and other) transporter Inositol_P PF00459.25 CBZ25106.1 - 4e-42 144.6 4.2 8.6e-23 81.2 0.9 2.2 2 0 0 2 2 2 2 Inositol monophosphatase family Kdo_hydroxy PF11004.8 CBZ25106.1 - 0.021 14.1 0.0 0.035 13.4 0.0 1.3 1 0 0 1 1 1 0 3-deoxy-D-manno-oct-2-ulosonic acid (Kdo) hydroxylase DUF4897 PF16238.5 CBZ25106.1 - 0.21 11.4 0.0 0.39 10.6 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4897) Hamartin PF04388.12 CBZ25106.1 - 0.96 8.0 6.2 1.4 7.5 6.2 1.1 1 0 0 1 1 1 0 Hamartin protein ABC2_membrane PF01061.24 CBZ25107.1 - 1.5e-38 132.3 19.8 2.5e-38 131.6 19.8 1.4 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.27 CBZ25107.1 - 1.7e-19 70.7 0.0 2.7e-19 70.0 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_16 PF13191.6 CBZ25107.1 - 0.0015 18.9 0.0 0.0029 18.0 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 CBZ25107.1 - 0.0047 17.2 0.0 0.01 16.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 CBZ25107.1 - 0.0061 16.5 0.0 0.011 15.6 0.0 1.3 1 0 0 1 1 1 1 RsgA GTPase AAA_23 PF13476.6 CBZ25107.1 - 0.013 16.0 0.1 0.022 15.3 0.1 1.3 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 CBZ25107.1 - 0.021 14.5 0.6 0.041 13.6 0.6 1.3 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 CBZ25107.1 - 0.027 14.2 0.4 0.057 13.2 0.4 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain PRK PF00485.18 CBZ25107.1 - 0.059 13.1 0.0 0.094 12.4 0.0 1.3 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family AAA_18 PF13238.6 CBZ25107.1 - 0.073 13.6 0.0 0.22 12.1 0.0 1.8 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 CBZ25107.1 - 0.074 13.0 0.0 0.17 11.8 0.0 1.6 1 0 0 1 1 1 0 NACHT domain RNA_helicase PF00910.22 CBZ25107.1 - 0.079 13.4 0.0 0.61 10.5 0.0 2.2 2 0 0 2 2 2 0 RNA helicase SMC_N PF02463.19 CBZ25107.1 - 0.11 12.0 0.0 9.8 5.5 0.0 2.2 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain NB-ARC PF00931.22 CBZ25107.1 - 0.12 11.6 0.0 0.19 10.9 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain MMR_HSR1 PF01926.23 CBZ25107.1 - 0.14 12.3 0.0 0.24 11.5 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_14 PF13173.6 CBZ25107.1 - 0.17 12.0 0.0 0.36 10.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_21 PF13304.6 CBZ25107.1 - 0.17 11.7 0.1 23 4.6 0.3 2.4 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_24 PF13479.6 CBZ25107.1 - 0.22 11.2 0.5 0.44 10.2 0.5 1.4 1 0 0 1 1 1 0 AAA domain ABC2_membrane_3 PF12698.7 CBZ25107.1 - 7.8 5.5 20.1 17 4.4 20.1 1.6 1 1 0 1 1 1 0 ABC-2 family transporter protein HEAT PF02985.22 CBZ25110.1 - 4.3e-19 67.0 21.8 0.0014 18.7 0.0 10.3 10 0 0 10 10 10 8 HEAT repeat HEAT_2 PF13646.6 CBZ25110.1 - 2.7e-17 62.9 21.3 4e-06 27.1 1.3 7.1 4 2 3 7 7 7 6 HEAT repeats Adaptin_N PF01602.20 CBZ25110.1 - 0.00052 18.7 4.2 0.034 12.7 0.1 3.2 2 2 0 2 2 2 2 Adaptin N terminal region Cnd1 PF12717.7 CBZ25110.1 - 0.00096 19.2 4.1 1.4 8.9 0.2 4.6 3 1 1 4 4 4 1 non-SMC mitotic condensation complex subunit 1 CLASP_N PF12348.8 CBZ25110.1 - 0.001 18.7 2.9 0.54 9.8 0.1 4.0 3 2 1 4 4 4 1 CLASP N terminal UME PF08064.13 CBZ25110.1 - 0.057 13.3 0.4 28 4.7 0.0 4.1 3 1 1 4 4 4 0 UME (NUC010) domain Arm PF00514.23 CBZ25110.1 - 0.22 11.6 3.3 17 5.6 0.1 3.8 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat Cohesin_HEAT PF12765.7 CBZ25110.1 - 0.25 11.7 2.4 0.56 10.6 0.1 2.6 2 0 0 2 2 2 0 HEAT repeat associated with sister chromatid cohesion EF-hand_9 PF14658.6 CBZ25111.1 - 3.7e-09 36.8 0.0 0.0072 16.6 0.0 3.2 2 1 1 3 3 3 2 EF-hand domain EF-hand_8 PF13833.6 CBZ25111.1 - 1.7e-08 34.2 0.0 0.039 13.8 0.0 3.2 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_7 PF13499.6 CBZ25111.1 - 6.7e-08 32.9 0.0 0.00013 22.3 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 CBZ25111.1 - 2.3e-06 27.1 0.0 0.29 11.2 0.0 3.6 4 0 0 4 4 4 2 EF-hand domain EF-hand_1 PF00036.32 CBZ25111.1 - 0.00021 20.6 0.0 2.1 8.1 0.0 3.4 3 0 0 3 3 3 2 EF hand DUF2087 PF09860.9 CBZ25111.1 - 0.015 15.4 0.0 0.88 9.8 0.0 2.4 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2087) Retrotran_gag_2 PF14223.6 CBZ25111.1 - 0.024 14.3 0.1 5.6 6.6 0.0 2.5 2 1 1 3 3 3 0 gag-polypeptide of LTR copia-type DUF2267 PF10025.9 CBZ25111.1 - 0.048 13.9 0.4 4.2 7.7 0.1 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2267) GPHH PF16905.5 CBZ25111.1 - 0.16 11.8 0.0 1.4 8.7 0.0 2.4 2 1 0 2 2 2 0 Voltage-dependent L-type calcium channel, IQ-associated MAP65_ASE1 PF03999.12 CBZ25112.1 - 1.1e-07 30.9 1.5 1.1e-07 30.9 1.5 2.1 2 0 0 2 2 2 1 Microtubule associated protein (MAP65/ASE1 family) Ribosomal_S3_C PF00189.20 CBZ25113.1 - 1.4e-19 70.4 1.8 1.4e-19 70.4 1.8 2.2 2 1 1 3 3 3 1 Ribosomal protein S3, C-terminal domain KH_2 PF07650.17 CBZ25113.1 - 9.5e-08 31.8 0.2 2.6e-07 30.3 0.2 1.7 2 0 0 2 2 2 1 KH domain Evr1_Alr PF04777.13 CBZ25114.1 - 3.4e-21 75.6 0.8 9e-21 74.2 0.8 1.7 1 0 0 1 1 1 1 Erv1 / Alr family ThiF PF00899.21 CBZ25115.1 - 4.5e-49 167.0 0.0 6.5e-49 166.5 0.0 1.1 1 0 0 1 1 1 1 ThiF family PglD_N PF17836.1 CBZ25115.1 - 0.002 18.8 0.0 0.0046 17.6 0.0 1.6 1 0 0 1 1 1 1 PglD N-terminal domain 2-Hacid_dh_C PF02826.19 CBZ25115.1 - 0.0045 16.4 0.0 0.01 15.2 0.0 1.6 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ApbA PF02558.16 CBZ25115.1 - 0.011 15.4 0.2 0.046 13.4 0.2 2.0 1 1 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Sacchrp_dh_NADP PF03435.18 CBZ25115.1 - 0.019 15.2 0.2 0.079 13.2 0.0 2.2 2 1 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain UDPG_MGDP_dh_N PF03721.14 CBZ25115.1 - 0.037 13.6 0.0 0.062 12.9 0.0 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain FAD_binding_3 PF01494.19 CBZ25115.1 - 0.047 12.9 0.3 0.047 12.9 0.3 1.6 2 0 0 2 2 2 0 FAD binding domain Shikimate_DH PF01488.20 CBZ25115.1 - 0.1 12.7 0.0 0.19 11.8 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Peptidase_M66 PF10462.9 CBZ25115.1 - 0.12 11.3 0.1 0.19 10.6 0.1 1.2 1 0 0 1 1 1 0 Peptidase M66 Rad9 PF04139.13 CBZ25116.1 - 3.2e-09 36.6 0.0 4.4e-06 26.3 0.0 2.1 2 0 0 2 2 2 2 Rad9 Fer4_17 PF13534.6 CBZ25117.1 - 4.6e-08 33.5 9.7 1e-06 29.2 1.3 1.7 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_8 PF13183.6 CBZ25117.1 - 1.4e-07 31.8 0.3 0.00052 20.4 0.3 2.2 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_10 PF13237.6 CBZ25117.1 - 0.0001 22.3 4.0 0.00026 21.0 4.0 1.6 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_9 PF13187.6 CBZ25117.1 - 0.0074 16.4 4.5 0.045 13.9 1.3 2.1 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_7 PF12838.7 CBZ25117.1 - 0.0077 16.8 1.9 0.023 15.3 1.9 1.8 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_4 PF12800.7 CBZ25117.1 - 0.014 15.9 4.8 0.051 14.1 1.0 2.3 2 0 0 2 2 2 0 4Fe-4S binding domain Ribosomal_L6e PF01159.19 CBZ25118.1 - 2.9e-30 105.1 0.4 1.7e-29 102.6 0.4 2.0 1 1 0 1 1 1 1 Ribosomal protein L6e KOW PF00467.29 CBZ25118.1 - 0.00095 19.0 0.0 0.0037 17.2 0.0 2.0 1 1 1 2 2 2 1 KOW motif ELFV_dehydrog PF00208.21 CBZ25119.1 - 1.7e-49 168.7 0.0 3.2e-49 167.9 0.0 1.4 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Bac_GDH PF05088.12 CBZ25119.1 - 3.6e-17 61.3 0.0 9e-09 33.5 0.0 2.1 2 0 0 2 2 2 2 Bacterial NAD-glutamate dehydrogenase polyprenyl_synt PF00348.17 CBZ25120.1 - 1.8e-61 207.5 0.0 2.2e-61 207.2 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase SQS_PSY PF00494.19 CBZ25120.1 - 0.078 12.5 0.5 0.17 11.3 0.5 1.8 1 1 0 1 1 1 0 Squalene/phytoene synthase SKIP_SNW PF02731.15 CBZ25121.1 - 3.4e-08 33.3 2.8 3.4e-08 33.3 2.8 3.0 2 1 1 3 3 3 1 SKIP/SNW domain GREB1 PF15782.5 CBZ25121.1 - 3.8 4.5 5.8 5.3 4.0 5.8 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer AhpC-TSA PF00578.21 CBZ25122.1 - 2.2e-35 121.3 0.0 2.8e-35 120.9 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 CBZ25122.1 - 3.8e-16 59.1 0.0 4.6e-16 58.9 0.0 1.1 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.9 CBZ25122.1 - 5.2e-14 51.8 0.1 1e-13 50.9 0.1 1.5 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin AhpC-TSA PF00578.21 CBZ25125.1 - 7.6e-37 126.0 0.0 9.8e-37 125.6 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 CBZ25125.1 - 2.6e-17 62.9 0.0 3.2e-17 62.6 0.0 1.1 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.9 CBZ25125.1 - 5.2e-14 51.8 0.1 1e-13 50.9 0.1 1.5 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin TFIIB_C_1 PF18542.1 CBZ25126.1 - 3.1e-41 139.4 1.5 3.1e-41 139.4 1.5 2.0 2 0 0 2 2 2 1 Transcription factor IIB C-terminal module 1 TF_Zn_Ribbon PF08271.12 CBZ25126.1 - 1.6e-05 24.3 1.4 2.9e-05 23.5 1.4 1.4 1 0 0 1 1 1 1 TFIIB zinc-binding Lar_restr_allev PF14354.6 CBZ25126.1 - 0.13 12.7 0.4 0.3 11.5 0.4 1.6 1 0 0 1 1 1 0 Restriction alleviation protein Lar zf-ribbon_3 PF13248.6 CBZ25126.1 - 0.17 11.3 1.7 0.88 9.1 0.2 2.3 2 0 0 2 2 2 0 zinc-ribbon domain cNMP_binding PF00027.29 CBZ25128.1 - 0.00015 21.8 0.0 0.016 15.3 0.0 2.6 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain Pkinase PF00069.25 CBZ25129.1 - 1.6e-57 194.9 0.0 2.5e-57 194.2 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ25129.1 - 7.3e-40 136.9 0.0 1.3e-39 136.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase cNMP_binding PF00027.29 CBZ25129.1 - 2.6e-28 97.9 1.9 1.6e-13 50.6 0.1 3.4 3 0 0 3 3 3 2 Cyclic nucleotide-binding domain Kinase-like PF14531.6 CBZ25129.1 - 3.7e-08 33.0 0.0 1.1e-06 28.2 0.0 2.3 2 0 0 2 2 2 1 Kinase-like PAS PF00989.25 CBZ25129.1 - 2.4e-07 30.7 0.0 9e-07 28.9 0.0 2.0 1 0 0 1 1 1 1 PAS fold PAS_9 PF13426.7 CBZ25129.1 - 0.00017 21.8 0.0 0.00064 19.9 0.0 2.1 1 0 0 1 1 1 1 PAS domain Ribosomal_60s PF00428.19 CBZ25130.1 - 5e-23 81.5 11.4 6.3e-23 81.2 11.4 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein Phage-MuB_C PF09077.11 CBZ25130.1 - 0.038 13.9 4.8 0.077 12.9 4.8 1.7 1 1 0 1 1 1 0 Mu B transposition protein, C terminal Ribosomal_60s PF00428.19 CBZ25131.1 - 5e-23 81.5 11.4 6.3e-23 81.2 11.4 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein Phage-MuB_C PF09077.11 CBZ25131.1 - 0.038 13.9 4.8 0.077 12.9 4.8 1.7 1 1 0 1 1 1 0 Mu B transposition protein, C terminal RhoGAP PF00620.27 CBZ25132.1 - 1.6e-11 44.2 0.0 3.1e-11 43.3 0.0 1.4 1 0 0 1 1 1 1 RhoGAP domain Exo_endo_phos PF03372.23 CBZ25132.1 - 4.3e-09 36.2 0.0 7.9e-09 35.4 0.0 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family DnaJ PF00226.31 CBZ25133.1 - 2.6e-26 91.5 1.4 4e-26 90.9 1.4 1.3 1 0 0 1 1 1 1 DnaJ domain DnaJ_C PF01556.18 CBZ25133.1 - 4.5e-19 69.0 0.0 4e-18 65.9 0.0 2.0 1 1 0 1 1 1 1 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.19 CBZ25133.1 - 7e-07 29.5 11.9 1.3e-06 28.7 11.9 1.4 1 0 0 1 1 1 1 DnaJ central domain SabA_adhesion PF18304.1 CBZ25133.1 - 0.22 10.8 0.0 0.33 10.2 0.0 1.1 1 0 0 1 1 1 0 SabA N-terminal extracellular adhesion domain Anti-TRAP PF15777.5 CBZ25133.1 - 0.53 10.3 13.0 0.35 10.9 2.3 2.5 2 0 0 2 2 2 0 Tryptophan RNA-binding attenuator protein inhibitory protein Nucleoside_tran PF01733.18 CBZ25134.1 - 1.2e-34 120.1 14.1 4.4e-34 118.3 8.9 2.9 2 1 0 2 2 2 2 Nucleoside transporter COX7a PF02238.15 CBZ25134.1 - 0.37 11.2 0.0 0.37 11.2 0.0 2.9 3 0 0 3 3 3 0 Cytochrome c oxidase subunit VII Nucleoside_tran PF01733.18 CBZ25135.1 - 2.4e-34 119.1 12.6 9.9e-34 117.1 8.2 2.8 2 1 0 2 2 2 1 Nucleoside transporter COX7a PF02238.15 CBZ25135.1 - 0.58 10.6 0.0 0.58 10.6 0.0 2.9 3 0 0 3 3 3 0 Cytochrome c oxidase subunit VII UFC1 PF08694.11 CBZ25136.1 - 7.9e-79 262.7 0.2 9e-79 262.5 0.2 1.0 1 0 0 1 1 1 1 Ubiquitin-fold modifier-conjugating enzyme 1 UQ_con PF00179.26 CBZ25136.1 - 0.00062 19.4 0.2 0.00089 18.9 0.2 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 CBZ25136.1 - 0.0085 16.4 0.0 0.01 16.1 0.0 1.2 1 0 0 1 1 1 1 RWD domain SET PF00856.28 CBZ25137.1 - 2.3e-08 34.6 0.0 7.1e-08 33.0 0.0 2.0 2 1 0 2 2 2 1 SET domain DUF433 PF04255.14 CBZ25137.1 - 0.098 12.5 0.4 11 6.0 0.0 3.3 3 1 0 3 3 3 0 Protein of unknown function (DUF433) Mac PF12464.8 CBZ25137.1 - 0.22 11.8 1.9 0.87 9.9 0.3 2.3 2 0 0 2 2 2 0 Maltose acetyltransferase DNA_topoisoIV PF00521.20 CBZ25140.1 - 1.3e-102 343.9 0.0 2.2e-102 343.2 0.0 1.4 1 0 0 1 1 1 1 DNA gyrase/topoisomerase IV, subunit A TOPRIM_C PF16898.5 CBZ25140.1 - 4.5e-31 107.8 1.2 4.5e-31 107.8 1.2 1.7 2 0 0 2 2 2 1 C-terminal associated domain of TOPRIM DNA_gyraseB PF00204.25 CBZ25140.1 - 1.9e-10 40.5 0.0 4.7e-10 39.2 0.0 1.6 1 0 0 1 1 1 1 DNA gyrase B HATPase_c PF02518.26 CBZ25140.1 - 1.4e-08 35.2 0.0 4.3e-08 33.7 0.0 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Toprim PF01751.22 CBZ25140.1 - 1.6e-07 31.5 0.0 6.6e-07 29.5 0.0 2.1 1 0 0 1 1 1 1 Toprim domain UCH PF00443.29 CBZ25141.1 - 1.1e-38 133.2 0.0 1.6e-38 132.7 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase USP7_ICP0_bdg PF12436.8 CBZ25141.1 - 1.4e-09 37.7 0.0 0.00054 19.3 0.0 3.1 2 1 0 2 2 2 2 ICP0-binding domain of Ubiquitin-specific protease 7 UCH_1 PF13423.6 CBZ25141.1 - 5.3e-09 36.1 0.0 0.0013 18.4 0.0 2.6 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase CorA PF01544.18 CBZ25142.1 - 1e-22 80.8 10.7 9.4e-21 74.4 3.6 2.3 1 1 1 2 2 2 2 CorA-like Mg2+ transporter protein SHOCT PF09851.9 CBZ25142.1 - 7.9e-05 22.3 0.1 0.00015 21.4 0.1 1.5 1 0 0 1 1 1 1 Short C-terminal domain Macoilin PF09726.9 CBZ25142.1 - 0.0074 14.9 3.4 0.011 14.3 3.4 1.2 1 0 0 1 1 1 1 Macoilin family DUF1645 PF07816.11 CBZ25142.1 - 0.26 11.9 22.9 0.046 14.3 16.7 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1645) Apt1 PF10351.9 CBZ25142.1 - 0.83 8.4 12.4 1.7 7.4 12.4 1.4 1 0 0 1 1 1 0 Golgi-body localisation protein domain DMAP_binding PF06464.11 CBZ25142.1 - 0.85 10.4 10.2 2.8 8.8 9.3 2.4 2 1 0 2 2 2 0 DMAP1-binding Domain MIF4G PF02854.19 CBZ25143.1 - 4.4e-10 39.6 0.0 1.1e-09 38.3 0.0 1.6 1 1 0 1 1 1 1 MIF4G domain Actin PF00022.19 CBZ25144.1 - 5.3e-100 334.9 0.0 8.3e-100 334.2 0.0 1.3 1 1 0 1 1 1 1 Actin MreB_Mbl PF06723.13 CBZ25144.1 - 0.011 14.6 0.0 0.16 10.8 0.0 2.3 2 0 0 2 2 2 0 MreB/Mbl protein NIF PF03031.18 CBZ25146.1 - 0.016 14.9 0.0 0.056 13.2 0.0 1.8 1 1 0 1 1 1 0 NLI interacting factor-like phosphatase RabGAP-TBC PF00566.18 CBZ25148.1 - 8.8e-07 28.8 0.3 1.7e-06 27.9 0.3 1.4 1 0 0 1 1 1 1 Rab-GTPase-TBC domain 2OG-FeII_Oxy PF03171.20 CBZ25149.1 - 0.01 16.3 0.0 0.33 11.5 0.0 2.4 1 1 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily Actin PF00022.19 CBZ25150.1 - 2.6e-71 240.4 0.0 1.1e-69 235.0 0.0 2.0 1 1 0 1 1 1 1 Actin MreB_Mbl PF06723.13 CBZ25150.1 - 1.1e-08 34.2 0.0 3.8e-08 32.5 0.0 1.8 1 1 0 1 1 1 1 MreB/Mbl protein Stomoxyn PF11585.8 CBZ25150.1 - 3.7 7.6 6.9 5.6 7.1 0.1 3.1 3 0 0 3 3 3 0 Insect antimicrobial peptide, stomoxyn DUF1796 PF08795.10 CBZ25151.1 - 9.2e-51 172.1 0.0 1.7e-50 171.3 0.0 1.4 1 0 0 1 1 1 1 Putative papain-like cysteine peptidase (DUF1796) Nop PF01798.18 CBZ25152.1 - 2e-81 272.8 0.6 2.7e-81 272.4 0.6 1.2 1 0 0 1 1 1 1 snoRNA binding domain, fibrillarin NOP5NT PF08156.13 CBZ25152.1 - 0.00013 22.2 0.5 0.18 12.2 0.1 2.9 1 1 1 2 2 2 2 NOP5NT (NUC127) domain RHH_6 PF16762.5 CBZ25152.1 - 0.31 11.7 3.6 24 5.7 0.5 3.3 2 1 1 3 3 3 0 Ribbon-helix-helix domain TMEM164 PF14808.6 CBZ25153.1 - 6.4e-10 38.8 2.0 8.3e-10 38.4 2.0 1.2 1 0 0 1 1 1 1 TMEM164 family MlaE PF02405.16 CBZ25153.1 - 0.015 15.0 0.3 0.085 12.5 0.2 2.1 2 0 0 2 2 2 0 Permease MlaE Alkyl_sulf_dimr PF14863.6 CBZ25154.1 - 0.014 15.9 0.1 0.023 15.1 0.1 1.3 1 0 0 1 1 1 0 Alkyl sulfatase dimerisation End3 PF12761.7 CBZ25154.1 - 0.15 12.2 1.7 0.23 11.6 1.7 1.2 1 0 0 1 1 1 0 Actin cytoskeleton-regulatory complex protein END3 zf-RING_2 PF13639.6 CBZ25155.1 - 8.6e-13 48.4 7.6 1.8e-12 47.4 7.6 1.6 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 CBZ25155.1 - 3.3e-07 29.9 2.5 7e-07 28.9 2.5 1.5 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 CBZ25155.1 - 9.4e-07 28.6 7.0 1.9e-06 27.6 7.0 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CBZ25155.1 - 9.5e-07 28.7 6.2 1.7e-06 27.9 6.2 1.4 1 0 0 1 1 1 1 RING-type zinc-finger zf-rbx1 PF12678.7 CBZ25155.1 - 1.1e-05 25.6 9.3 2.6e-05 24.4 9.3 1.7 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_3 PF13920.6 CBZ25155.1 - 2.2e-05 24.2 5.7 3.9e-05 23.4 5.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CBZ25155.1 - 0.00018 21.3 6.1 0.00033 20.4 6.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CBZ25155.1 - 0.0024 17.8 5.7 0.0044 16.9 5.7 1.5 1 0 0 1 1 1 1 zinc-RING finger domain FANCL_C PF11793.8 CBZ25155.1 - 0.016 15.4 7.3 0.34 11.1 7.3 2.5 1 1 0 1 1 1 0 FANCL C-terminal domain zf-ANAPC11 PF12861.7 CBZ25155.1 - 0.026 14.6 4.6 0.062 13.4 4.6 1.6 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.6 CBZ25155.1 - 0.029 14.2 5.3 0.063 13.1 5.3 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 Zn_ribbon_17 PF17120.5 CBZ25155.1 - 0.068 12.8 4.9 0.14 11.8 4.9 1.5 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type Imm_superinfect PF14373.6 CBZ25155.1 - 0.087 12.8 1.6 0.2 11.6 1.6 1.6 1 0 0 1 1 1 0 Superinfection immunity protein zinc_ribbon_16 PF17034.5 CBZ25155.1 - 0.22 11.8 1.6 0.45 10.7 1.6 1.4 1 0 0 1 1 1 0 Zinc-ribbon like family zf-RING_4 PF14570.6 CBZ25155.1 - 0.58 10.0 6.6 1.3 8.9 6.6 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain DUF5337 PF17272.2 CBZ25155.1 - 1.9 8.4 8.1 0.086 12.7 0.6 2.6 3 0 0 3 3 3 0 Family of unknown function (DUF5337) zf-RING-like PF08746.11 CBZ25155.1 - 1.9 8.8 6.3 3.7 7.9 6.3 1.5 1 0 0 1 1 1 0 RING-like domain MutS_V PF00488.21 CBZ25156.1 - 2.1e-49 168.1 0.0 1.3e-48 165.6 0.0 2.0 1 1 0 1 1 1 1 MutS domain V MutS_III PF05192.18 CBZ25156.1 - 7.1e-22 78.6 0.0 1.1e-21 77.9 0.0 1.3 1 0 0 1 1 1 1 MutS domain III MutS_I PF01624.20 CBZ25156.1 - 1.3e-19 70.5 0.0 2.2e-19 69.8 0.0 1.4 1 0 0 1 1 1 1 MutS domain I MutS_IV PF05190.18 CBZ25156.1 - 0.0038 17.5 0.0 0.0066 16.8 0.0 1.3 1 0 0 1 1 1 1 MutS family domain IV tRNA-synt_1c PF00749.21 CBZ25158.1 - 4.6e-104 347.7 0.0 6.1e-104 347.3 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.18 CBZ25158.1 - 1.5e-40 138.9 0.0 2.5e-40 138.2 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain PCNA_N PF00705.18 CBZ25159.1 - 5.1e-42 142.6 1.6 8.4e-42 141.9 1.0 1.6 2 0 0 2 2 2 1 Proliferating cell nuclear antigen, N-terminal domain PCNA_C PF02747.15 CBZ25159.1 - 6.7e-38 129.8 0.1 1.8e-19 70.2 0.1 2.3 2 0 0 2 2 2 2 Proliferating cell nuclear antigen, C-terminal domain Rad9 PF04139.13 CBZ25159.1 - 2.7e-07 30.3 0.0 3.4e-07 30.0 0.0 1.3 1 0 0 1 1 1 1 Rad9 Rad1 PF02144.16 CBZ25159.1 - 0.00037 19.7 0.1 0.007 15.5 0.1 2.1 1 1 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 Hus1 PF04005.12 CBZ25159.1 - 0.022 13.9 0.0 0.33 10.0 0.0 2.1 2 0 0 2 2 2 0 Hus1-like protein Diphthami_syn_2 PF01902.17 CBZ25159.1 - 0.071 12.6 0.0 0.15 11.5 0.0 1.5 1 0 0 1 1 1 0 Diphthamide synthase GHMP_kinases_N PF00288.26 CBZ25160.1 - 4.4e-14 52.5 1.3 1.4e-13 50.8 1.3 1.9 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 CBZ25160.1 - 1.2e-06 28.8 0.2 5.1e-05 23.6 0.1 2.5 2 0 0 2 2 2 1 GHMP kinases C terminal Gpr1_Fun34_YaaH PF01184.19 CBZ25161.1 - 0.0034 17.0 0.1 0.0038 16.8 0.1 1.1 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family ICE2 PF08426.10 CBZ25161.1 - 0.035 13.2 0.0 0.044 12.9 0.0 1.1 1 0 0 1 1 1 0 ICE2 Ribosomal_L7Ae PF01248.26 CBZ25162.1 - 4.2e-25 87.3 0.1 4.9e-25 87.1 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family PELOTA_1 PF15608.6 CBZ25162.1 - 3.2e-05 23.7 0.0 4.9e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 PELOTA RNA binding domain RNase_P_pop3 PF08228.11 CBZ25162.1 - 0.0014 18.7 0.2 0.0015 18.6 0.2 1.1 1 0 0 1 1 1 1 RNase P subunit Pop3 PDEase_I PF00233.19 CBZ25163.1 - 2.1e-69 233.9 0.0 4.4e-69 232.8 0.0 1.6 2 0 0 2 2 2 1 3'5'-cyclic nucleotide phosphodiesterase GAF PF01590.26 CBZ25163.1 - 1.1e-30 107.0 0.1 4.1e-15 56.6 0.0 3.3 3 0 0 3 3 3 2 GAF domain GAF_2 PF13185.6 CBZ25163.1 - 1.1e-18 67.9 0.0 1.2e-06 28.8 0.0 3.6 3 0 0 3 3 3 3 GAF domain GAF_3 PF13492.6 CBZ25163.1 - 5e-11 43.0 0.1 0.0018 18.6 0.0 3.8 3 1 0 3 3 3 3 GAF domain PDEase_I PF00233.19 CBZ25164.1 - 8.8e-70 235.1 0.1 1.8e-69 234.1 0.0 1.6 2 0 0 2 2 2 1 3'5'-cyclic nucleotide phosphodiesterase GAF PF01590.26 CBZ25164.1 - 9.3e-30 104.0 0.1 1.7e-14 54.6 0.0 3.4 3 0 0 3 3 3 2 GAF domain GAF_2 PF13185.6 CBZ25164.1 - 5.2e-17 62.4 0.0 2.7e-06 27.7 0.0 3.5 3 0 0 3 3 3 2 GAF domain GAF_3 PF13492.6 CBZ25164.1 - 4.1e-08 33.6 0.0 0.018 15.3 0.0 3.2 3 0 0 3 3 3 2 GAF domain DUF58 PF01882.18 CBZ25164.1 - 0.01 16.1 1.8 3.4 8.0 0.2 3.1 3 0 0 3 3 3 0 Protein of unknown function DUF58 Sld5 PF05916.11 CBZ25167.1 - 0.037 14.5 0.0 0.056 13.9 0.0 1.4 1 0 0 1 1 1 0 GINS complex protein SMRP1 PF15181.6 CBZ25167.1 - 0.043 13.4 0.3 0.065 12.8 0.3 1.3 1 0 0 1 1 1 0 Spermatid-specific manchette-related protein 1 Presenilin PF01080.17 CBZ25169.1 - 6.8e-75 252.3 34.5 8.8e-53 179.5 21.0 2.0 1 1 1 2 2 2 2 Presenilin Wyosine_form PF08608.12 CBZ25170.1 - 7.7e-18 64.6 0.0 2e-17 63.3 0.0 1.8 1 0 0 1 1 1 1 Wyosine base formation Radical_SAM PF04055.21 CBZ25170.1 - 5.4e-16 59.4 0.0 1e-15 58.5 0.0 1.6 1 1 0 1 1 1 1 Radical SAM superfamily Paf67 PF10255.9 CBZ25170.1 - 0.2 10.6 0.0 0.32 9.9 0.0 1.2 1 0 0 1 1 1 0 RNA polymerase I-associated factor PAF67 Pkinase PF00069.25 CBZ25172.1 - 3.1e-57 193.9 0.0 4.1e-57 193.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ25172.1 - 2.2e-26 92.7 0.0 1.5e-25 90.0 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase FYVE PF01363.21 CBZ25172.1 - 5.4e-15 55.3 3.7 1.2e-14 54.1 3.7 1.6 1 0 0 1 1 1 1 FYVE zinc finger APH PF01636.23 CBZ25172.1 - 0.00021 21.3 0.1 0.0027 17.7 0.0 2.0 1 1 1 2 2 2 1 Phosphotransferase enzyme family FYVE_2 PF02318.16 CBZ25172.1 - 0.0016 18.6 2.8 0.0016 18.6 2.8 2.1 2 0 0 2 2 2 1 FYVE-type zinc finger Pkinase_fungal PF17667.1 CBZ25172.1 - 0.0053 15.6 0.0 0.0077 15.0 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase DZR PF12773.7 CBZ25172.1 - 0.095 12.7 0.2 0.095 12.7 0.2 2.8 3 0 0 3 3 3 0 Double zinc ribbon Choline_kinase PF01633.20 CBZ25172.1 - 0.13 11.9 0.0 0.22 11.1 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase Cnd1 PF12717.7 CBZ25173.1 - 2e-19 70.2 2.8 5.4e-17 62.3 0.1 4.0 3 1 1 4 4 4 1 non-SMC mitotic condensation complex subunit 1 Cnd1_N PF12922.7 CBZ25173.1 - 0.00013 21.9 0.0 0.00095 19.0 0.0 2.3 2 0 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1, N-term HEAT PF02985.22 CBZ25173.1 - 0.00033 20.6 4.2 9.3 6.8 0.0 5.7 6 0 0 6 6 6 1 HEAT repeat Cnd3 PF12719.7 CBZ25173.1 - 0.00073 18.8 1.0 0.027 13.7 0.1 2.8 3 0 0 3 3 3 1 Nuclear condensing complex subunits, C-term domain HEAT_2 PF13646.6 CBZ25173.1 - 0.0055 17.1 5.4 27 5.2 0.0 5.5 4 2 2 6 6 6 0 HEAT repeats Nipped-B_C PF12830.7 CBZ25173.1 - 0.026 14.4 0.4 11 5.8 0.0 3.4 3 0 0 3 3 3 0 Sister chromatid cohesion C-terminus DUF2647 PF10839.8 CBZ25173.1 - 0.035 14.1 0.1 19 5.4 0.0 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2647) SR-25 PF10500.9 CBZ25174.1 - 0.014 15.0 8.1 0.024 14.2 8.1 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein YL1 PF05764.13 CBZ25174.1 - 0.023 14.8 8.5 0.04 14.0 8.5 1.4 1 0 0 1 1 1 0 YL1 nuclear protein SDA1 PF05285.12 CBZ25174.1 - 0.52 9.7 8.6 0.69 9.3 8.6 1.2 1 0 0 1 1 1 0 SDA1 CDC45 PF02724.14 CBZ25174.1 - 0.59 8.4 7.5 0.74 8.0 7.5 1.1 1 0 0 1 1 1 0 CDC45-like protein ASF1_hist_chap PF04729.13 CBZ25175.1 - 5.3e-25 88.2 0.0 6.2e-25 87.9 0.0 1.1 1 0 0 1 1 1 1 ASF1 like histone chaperone DUF5597 PF18120.1 CBZ25175.1 - 0.092 12.9 0.0 0.12 12.5 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5597) Ribosomal_L27A PF00828.19 CBZ25176.1 - 3.6e-07 30.9 0.0 5.9e-07 30.2 0.0 1.3 1 0 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A ADK PF00406.22 CBZ25177.1 - 5e-11 42.9 0.1 4.3e-06 26.9 0.0 2.2 1 1 1 2 2 2 2 Adenylate kinase AAA_17 PF13207.6 CBZ25177.1 - 3.2e-07 30.9 0.2 0.00058 20.3 0.3 2.3 1 1 1 2 2 2 2 AAA domain RuvB_N PF05496.12 CBZ25177.1 - 4.2e-05 23.3 0.0 6.6e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_18 PF13238.6 CBZ25177.1 - 7.1e-05 23.4 0.0 0.00014 22.4 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.6 CBZ25177.1 - 0.00021 21.6 0.9 0.00054 20.2 0.1 2.1 3 0 0 3 3 1 1 AAA domain AAA_33 PF13671.6 CBZ25177.1 - 0.00046 20.4 0.3 0.0015 18.7 0.1 1.8 1 1 1 2 2 2 1 AAA domain DUF5582 PF17819.1 CBZ25177.1 - 0.0005 20.5 0.5 0.0016 18.9 0.1 1.8 2 0 0 2 2 2 1 Family of unknown function (DUF5582) AAA_16 PF13191.6 CBZ25177.1 - 0.00073 20.0 0.2 0.0015 18.9 0.2 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.14 CBZ25177.1 - 0.002 18.2 0.0 0.0063 16.5 0.0 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 CBZ25177.1 - 0.0042 17.4 0.0 0.0099 16.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain SRP54 PF00448.22 CBZ25177.1 - 0.0074 15.9 0.0 0.011 15.4 0.0 1.4 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain Zeta_toxin PF06414.12 CBZ25177.1 - 0.0076 15.5 0.0 0.096 12.0 0.0 2.3 2 0 0 2 2 2 1 Zeta toxin ABC_tran PF00005.27 CBZ25177.1 - 0.0089 16.5 0.0 0.019 15.4 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA PF00004.29 CBZ25177.1 - 0.012 16.0 0.1 0.024 15.1 0.1 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 CBZ25177.1 - 0.016 14.7 0.2 0.026 14.0 0.2 1.3 1 0 0 1 1 1 0 PhoH-like protein NACHT PF05729.12 CBZ25177.1 - 0.016 15.1 0.0 0.028 14.3 0.0 1.4 1 0 0 1 1 1 0 NACHT domain Guanylate_kin PF00625.21 CBZ25177.1 - 0.019 14.7 0.0 6.6 6.4 0.0 2.2 1 1 1 2 2 2 0 Guanylate kinase TsaE PF02367.17 CBZ25177.1 - 0.019 15.0 0.0 0.035 14.1 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Thymidylate_kin PF02223.17 CBZ25177.1 - 0.02 14.6 0.0 3.4 7.3 0.0 2.3 2 0 0 2 2 2 0 Thymidylate kinase SRPRB PF09439.10 CBZ25177.1 - 0.02 14.3 0.0 0.035 13.5 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit ResIII PF04851.15 CBZ25177.1 - 0.027 14.5 0.0 0.04 13.9 0.0 1.3 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit dNK PF01712.19 CBZ25177.1 - 0.029 14.2 0.0 0.053 13.4 0.0 1.4 1 0 0 1 1 1 0 Deoxynucleoside kinase AAA_3 PF07726.11 CBZ25177.1 - 0.043 13.7 0.0 0.077 12.9 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.6 CBZ25177.1 - 0.043 13.5 0.1 0.072 12.8 0.1 1.4 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 CBZ25177.1 - 0.052 13.1 0.0 0.092 12.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 CBZ25177.1 - 0.057 13.1 0.1 0.09 12.5 0.1 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein FtsK_SpoIIIE PF01580.18 CBZ25177.1 - 0.058 12.7 0.0 0.091 12.1 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family T2SSE PF00437.20 CBZ25177.1 - 0.058 12.4 0.0 0.09 11.8 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein GTP_EFTU PF00009.27 CBZ25177.1 - 0.058 12.9 0.0 0.095 12.2 0.0 1.4 1 0 0 1 1 1 0 Elongation factor Tu GTP binding domain Ploopntkinase3 PF18751.1 CBZ25177.1 - 0.06 13.3 0.0 0.13 12.2 0.0 1.5 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 cobW PF02492.19 CBZ25177.1 - 0.067 12.8 0.2 0.2 11.3 0.2 1.7 1 1 1 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_30 PF13604.6 CBZ25177.1 - 0.077 12.7 0.1 0.11 12.2 0.1 1.3 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 CBZ25177.1 - 0.08 12.7 0.0 0.15 11.8 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain PduV-EutP PF10662.9 CBZ25177.1 - 0.085 12.6 0.0 0.16 11.7 0.0 1.4 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation ATP_bind_1 PF03029.17 CBZ25177.1 - 0.089 12.6 0.2 0.19 11.5 0.2 1.5 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein Mg_chelatase PF01078.21 CBZ25177.1 - 0.092 12.1 0.0 0.16 11.3 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Cytidylate_kin PF02224.18 CBZ25177.1 - 0.097 12.4 0.1 0.29 10.8 0.1 1.8 2 0 0 2 2 2 0 Cytidylate kinase AAA_19 PF13245.6 CBZ25177.1 - 0.13 12.6 0.1 0.23 11.8 0.1 1.3 1 0 0 1 1 1 0 AAA domain Sigma54_activ_2 PF14532.6 CBZ25177.1 - 0.16 12.1 0.0 0.28 11.3 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_14 PF13173.6 CBZ25177.1 - 0.17 11.9 0.0 0.39 10.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.22 CBZ25177.1 - 0.18 11.0 0.0 0.34 10.1 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain Hydin_ADK PF17213.3 CBZ25177.1 - 1.1 9.5 6.1 0.13 12.5 1.1 2.1 2 2 1 3 3 1 0 Hydin Adenylate kinase-like domain PrmA PF06325.13 CBZ25178.1 - 1.4e-05 24.7 0.1 2e-05 24.1 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 CBZ25178.1 - 0.02 14.4 0.0 0.038 13.5 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_18 PF12847.7 CBZ25178.1 - 0.071 13.0 0.0 0.12 12.3 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain CMAS PF02353.20 CBZ25178.1 - 0.09 12.1 0.0 0.17 11.2 0.0 1.4 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_25 PF13649.6 CBZ25178.1 - 0.12 13.1 0.1 0.26 12.0 0.1 1.5 1 0 0 1 1 1 0 Methyltransferase domain 2OG-FeII_Oxy_3 PF13640.6 CBZ25179.1 - 1.1e-11 45.4 0.1 5.4e-11 43.2 0.1 2.0 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily PhyH PF05721.13 CBZ25179.1 - 0.0001 22.6 0.0 0.00019 21.7 0.0 1.4 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Pox_C4_C10 PF03336.13 CBZ25179.1 - 0.05 12.7 0.0 0.62 9.1 0.0 2.2 2 1 0 2 2 2 0 Poxvirus C4/C10 protein TPR_6 PF13174.6 CBZ25179.1 - 0.14 12.9 0.1 0.38 11.5 0.1 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat 2OG-FeII_Oxy PF03171.20 CBZ25179.1 - 0.15 12.5 0.0 0.36 11.3 0.0 1.6 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily DEAD PF00270.29 CBZ25180.1 - 1e-15 58.0 0.0 9.6e-14 51.5 0.0 2.3 1 1 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CBZ25180.1 - 8.7e-14 51.8 0.0 5e-13 49.4 0.0 2.4 2 1 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 CBZ25180.1 - 0.12 12.3 0.0 0.36 10.8 0.0 1.9 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit AAA PF00004.29 CBZ25181.1 - 2.7e-45 154.1 0.0 6.8e-45 152.7 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 CBZ25181.1 - 2.4e-06 27.4 0.0 5.7e-06 26.2 0.0 1.7 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 CBZ25181.1 - 0.00015 22.2 1.2 0.0063 16.9 0.0 3.3 2 1 1 3 3 3 1 AAA ATPase domain AAA_2 PF07724.14 CBZ25181.1 - 0.0002 21.5 0.0 0.00044 20.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) Vps4_C PF09336.10 CBZ25181.1 - 0.00032 20.6 0.0 0.00082 19.3 0.0 1.7 1 0 0 1 1 1 1 Vps4 C terminal oligomerisation domain AAA_33 PF13671.6 CBZ25181.1 - 0.0019 18.4 0.0 0.0081 16.3 0.0 2.1 3 0 0 3 3 1 1 AAA domain Parvo_NS1 PF01057.17 CBZ25181.1 - 0.0031 16.6 0.0 0.0052 15.9 0.0 1.2 1 0 0 1 1 1 1 Parvovirus non-structural protein NS1 AAA_22 PF13401.6 CBZ25181.1 - 0.0038 17.5 0.0 0.15 12.4 0.1 2.7 2 1 0 2 2 2 1 AAA domain AAA_5 PF07728.14 CBZ25181.1 - 0.0052 16.8 0.0 0.018 15.0 0.0 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) RNA_helicase PF00910.22 CBZ25181.1 - 0.0052 17.2 0.0 0.012 16.0 0.0 1.6 1 0 0 1 1 1 1 RNA helicase AAA_14 PF13173.6 CBZ25181.1 - 0.0056 16.7 0.0 0.01 15.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_lid_3 PF17862.1 CBZ25181.1 - 0.007 16.2 0.1 0.054 13.3 0.0 2.7 2 0 0 2 2 1 1 AAA+ lid domain AAA_7 PF12775.7 CBZ25181.1 - 0.015 14.8 0.0 0.028 13.9 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region TIP49 PF06068.13 CBZ25181.1 - 0.02 14.1 0.0 0.032 13.4 0.0 1.2 1 0 0 1 1 1 0 TIP49 P-loop domain Mg_chelatase PF01078.21 CBZ25181.1 - 0.02 14.3 0.1 0.038 13.4 0.1 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 CBZ25181.1 - 0.023 14.4 0.0 0.053 13.3 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein TsaE PF02367.17 CBZ25181.1 - 0.023 14.7 0.0 0.044 13.8 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE ABC_tran PF00005.27 CBZ25181.1 - 0.025 15.1 0.0 0.049 14.2 0.0 1.4 1 0 0 1 1 1 0 ABC transporter ATPase PF06745.13 CBZ25181.1 - 0.062 12.6 0.0 0.12 11.6 0.0 1.4 1 0 0 1 1 1 0 KaiC AAA_28 PF13521.6 CBZ25181.1 - 0.077 13.2 0.0 0.3 11.3 0.0 2.0 2 0 0 2 2 1 0 AAA domain AAA_25 PF13481.6 CBZ25181.1 - 0.08 12.5 0.0 0.69 9.5 0.0 2.4 2 0 0 2 2 2 0 AAA domain PhoH PF02562.16 CBZ25181.1 - 0.094 12.1 0.0 0.18 11.2 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein AAA_17 PF13207.6 CBZ25181.1 - 0.15 12.5 0.0 0.43 11.0 0.0 1.8 1 0 0 1 1 1 0 AAA domain Rad17 PF03215.15 CBZ25181.1 - 0.18 11.7 0.0 0.33 10.8 0.0 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain Kelch_4 PF13418.6 CBZ25183.1 - 6.9e-34 115.6 0.2 2.4e-09 37.1 0.0 6.6 6 0 0 6 6 6 6 Galactose oxidase, central domain Kelch_5 PF13854.6 CBZ25183.1 - 1.4e-28 98.3 1.6 0.00061 19.7 0.0 6.4 6 0 0 6 6 6 5 Kelch motif Kelch_6 PF13964.6 CBZ25183.1 - 7.7e-25 86.3 4.8 4.8e-05 23.5 0.0 6.4 5 1 1 6 6 6 6 Kelch motif Kelch_3 PF13415.6 CBZ25183.1 - 2.2e-22 78.8 5.8 0.0024 18.1 0.0 6.8 6 1 0 6 6 6 6 Galactose oxidase, central domain DUF4110 PF13422.6 CBZ25183.1 - 9.3e-20 70.5 10.4 9.3e-20 70.5 10.4 3.1 3 0 0 3 3 3 1 Domain of unknown function (DUF4110) Kelch_1 PF01344.25 CBZ25183.1 - 1.8e-19 69.0 0.1 8.1e-06 25.3 0.0 4.9 5 0 0 5 5 5 4 Kelch motif Kelch_2 PF07646.15 CBZ25183.1 - 7.4e-16 57.4 2.7 0.0038 17.1 0.0 6.3 6 0 0 6 6 6 4 Kelch motif MORN PF02493.20 CBZ25185.1 - 3.1e-13 48.8 8.1 3.7e-08 32.8 0.8 4.6 4 0 0 4 4 4 2 MORN repeat KCH PF16944.5 CBZ25185.1 - 0.0015 18.4 0.1 0.0015 18.4 0.1 2.1 2 0 0 2 2 2 1 Fungal potassium channel FANCA_interact PF15751.5 CBZ25185.1 - 0.18 12.3 0.8 0.32 11.5 0.2 1.7 2 0 0 2 2 2 0 FAAP20 FANCA interaction domain MARVEL PF01284.23 CBZ25185.1 - 5.6 7.0 23.0 1.7 8.6 1.1 4.6 4 1 1 5 5 5 0 Membrane-associating domain APH PF01636.23 CBZ25186.1 - 7.5e-13 49.0 0.0 2.4e-12 47.3 0.0 1.8 1 1 0 1 1 1 1 Phosphotransferase enzyme family eIF-1a PF01176.19 CBZ25190.1 - 1.4e-12 47.2 0.3 2.1e-12 46.6 0.3 1.3 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 Ribosomal_L17 PF01196.19 CBZ25192.1 - 9.6e-13 48.9 0.1 1.4e-12 48.3 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L17 Mfa1 PF17445.2 CBZ25194.1 - 0.28 11.2 2.4 2.4 8.3 0.1 2.4 2 0 0 2 2 2 0 Mating factor A1 Las1 PF04031.13 CBZ25195.1 - 2.9e-32 111.9 0.1 5e-32 111.1 0.1 1.4 1 0 0 1 1 1 1 Las1-like DUF5337 PF17272.2 CBZ25195.1 - 0.017 14.9 0.1 0.035 13.9 0.1 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5337) INO80_Ies4 PF08193.11 CBZ25195.1 - 2.4 8.1 10.2 0.35 10.8 0.2 2.5 2 1 1 3 3 3 0 INO80 complex subunit Ies4 Mito_carr PF00153.27 CBZ25196.1 - 8.2e-60 198.8 0.5 1.9e-19 69.3 0.0 3.0 2 1 1 3 3 3 3 Mitochondrial carrier protein Mito_carr PF00153.27 CBZ25197.1 - 4.5e-51 170.7 3.4 3.2e-17 62.2 0.1 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein MAP65_ASE1 PF03999.12 CBZ25197.1 - 0.064 12.0 0.0 0.083 11.6 0.0 1.1 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) DSPc PF00782.20 CBZ25199.1 - 1.4e-07 31.4 0.0 2e-07 30.9 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 CBZ25199.1 - 0.00011 21.9 0.0 0.00013 21.6 0.0 1.1 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Radical_SAM_C PF16199.5 CBZ25200.1 - 4.6e-21 74.6 0.3 2.3e-20 72.4 0.1 2.1 2 0 0 2 2 2 1 Radical_SAM C-terminal domain Radical_SAM PF04055.21 CBZ25200.1 - 2.5e-15 57.2 0.0 8.9e-15 55.5 0.0 1.9 2 0 0 2 2 2 1 Radical SAM superfamily Acetyltransf_1 PF00583.25 CBZ25200.1 - 4.7e-07 30.1 0.1 1.3e-06 28.6 0.1 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 CBZ25200.1 - 7.7e-05 22.6 0.1 0.00015 21.7 0.1 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 CBZ25200.1 - 0.13 12.7 0.3 0.29 11.6 0.3 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain CheZ PF04344.13 CBZ25200.1 - 0.15 12.0 0.1 0.25 11.2 0.1 1.3 1 0 0 1 1 1 0 Chemotaxis phosphatase, CheZ DSPc PF00782.20 CBZ25201.1 - 6.4e-08 32.5 0.0 7.5e-08 32.3 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 CBZ25201.1 - 2.7e-05 23.8 0.0 3.1e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Hydrolase_4 PF12146.8 CBZ25202.1 - 7.1e-13 48.4 1.0 1.3e-06 27.9 0.7 2.3 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 CBZ25202.1 - 2.8e-09 37.0 0.1 4.2e-06 26.6 0.1 2.5 1 1 1 2 2 2 2 alpha/beta hydrolase fold Ank_2 PF12796.7 CBZ25202.1 - 9.5e-09 35.7 0.1 1.8e-07 31.6 0.0 2.4 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CBZ25202.1 - 4e-08 33.6 1.4 0.00033 21.2 0.1 3.4 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Abhydrolase_6 PF12697.7 CBZ25202.1 - 6.3e-08 33.5 0.0 1.2e-07 32.5 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Ank_3 PF13606.6 CBZ25202.1 - 3.6e-07 30.0 0.2 6.3e-05 23.1 0.1 3.7 3 0 0 3 3 3 1 Ankyrin repeat Peptidase_S9 PF00326.21 CBZ25202.1 - 1.9e-06 27.5 0.1 0.033 13.6 0.0 2.3 2 0 0 2 2 2 2 Prolyl oligopeptidase family Ank_5 PF13857.6 CBZ25202.1 - 6.9e-06 26.2 0.2 0.00044 20.5 0.0 2.8 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank PF00023.30 CBZ25202.1 - 1.4e-05 25.4 0.1 0.00025 21.4 0.1 3.0 3 0 0 3 3 3 1 Ankyrin repeat AXE1 PF05448.12 CBZ25202.1 - 9.3e-05 21.2 0.7 0.034 12.8 0.7 2.3 1 1 0 1 1 1 1 Acetyl xylan esterase (AXE1) Peptidase_S15 PF02129.18 CBZ25202.1 - 0.0016 18.1 0.0 0.034 13.7 0.1 2.1 1 1 1 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) Say1_Mug180 PF10340.9 CBZ25202.1 - 0.021 13.7 0.0 4.1 6.2 0.0 2.1 2 0 0 2 2 2 0 Steryl acetyl hydrolase BAAT_C PF08840.11 CBZ25202.1 - 0.059 13.3 0.0 0.12 12.3 0.0 1.5 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal RIH_assoc PF08454.11 CBZ25204.1 - 1.7e-19 69.5 1.2 5.1e-19 68.0 0.4 2.3 2 0 0 2 2 2 1 RyR and IP3R Homology associated Ins145_P3_rec PF08709.11 CBZ25204.1 - 3.2e-12 46.1 0.0 3e-11 43.0 0.0 2.5 1 1 1 3 3 3 1 Inositol 1,4,5-trisphosphate/ryanodine receptor Ion_trans PF00520.31 CBZ25204.1 - 1.3e-06 27.8 12.5 3.6e-06 26.4 12.5 1.8 1 1 0 1 1 1 1 Ion transport protein MIR PF02815.19 CBZ25204.1 - 0.0011 18.9 0.0 0.29 11.0 0.0 2.4 2 0 0 2 2 2 2 MIR domain RYDR_ITPR PF01365.21 CBZ25204.1 - 0.011 15.1 0.0 0.054 12.9 0.0 2.2 1 0 0 1 1 1 0 RIH domain Nas2_N PF18265.1 CBZ25205.1 - 1.5e-22 79.3 0.0 3e-22 78.3 0.0 1.5 1 0 0 1 1 1 1 Nas2 N_terminal domain PDZ_6 PF17820.1 CBZ25205.1 - 0.00083 19.2 0.1 0.0019 18.0 0.1 1.7 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 CBZ25205.1 - 0.0048 17.2 0.0 0.012 16.0 0.0 1.6 1 0 0 1 1 1 1 PDZ domain COMMD1_N PF17221.3 CBZ25205.1 - 0.016 15.5 1.8 0.016 15.5 1.8 1.8 2 0 0 2 2 2 0 COMMD1 N-terminal domain GRASP55_65 PF04495.14 CBZ25205.1 - 0.038 14.3 0.0 0.1 12.9 0.0 1.7 1 1 0 1 1 1 0 GRASP55/65 PDZ-like domain DUF4407 PF14362.6 CBZ25205.1 - 0.12 11.7 6.0 0.16 11.3 6.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) RHH_3 PF12651.7 CBZ25205.1 - 0.17 11.8 0.4 1.8 8.6 0.1 2.2 2 0 0 2 2 2 0 Ribbon-helix-helix domain Erythro_esteras PF05139.14 CBZ25205.1 - 3.5 7.4 9.4 12 5.6 9.4 1.7 1 1 0 1 1 1 0 Erythromycin esterase KfrA_N PF11740.8 CBZ25205.1 - 3.9 8.2 16.7 5.4 7.7 10.6 2.3 2 0 0 2 2 2 0 Plasmid replication region DNA-binding N-term Pkinase PF00069.25 CBZ25206.1 - 9.1e-67 225.2 0.0 1.2e-66 224.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ25206.1 - 4.2e-49 167.1 0.0 5.6e-49 166.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CBZ25206.1 - 3.1e-05 22.9 0.0 4.5e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 CBZ25206.1 - 0.033 13.5 0.0 0.1 11.9 0.0 1.8 2 0 0 2 2 2 0 Kinase-like FMN_bind PF04205.14 CBZ25206.1 - 0.033 14.8 3.1 0.7 10.5 0.4 2.7 1 1 1 2 2 2 0 FMN-binding domain Met_10 PF02475.16 CBZ25207.1 - 2.1e-47 161.5 0.0 3.4e-35 121.6 0.0 2.2 2 0 0 2 2 2 2 Met-10+ like-protein PrmA PF06325.13 CBZ25207.1 - 0.0015 18.0 0.0 0.0025 17.3 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) TRM PF02005.16 CBZ25207.1 - 0.088 12.0 0.0 0.14 11.3 0.0 1.2 1 0 0 1 1 1 0 N2,N2-dimethylguanosine tRNA methyltransferase FHA PF00498.26 CBZ25208.1 - 1.2e-13 51.2 0.0 3.8e-13 49.6 0.0 2.0 2 0 0 2 2 2 1 FHA domain Oxidored_q6 PF01058.22 CBZ25209.1 - 0.13 12.1 0.0 0.22 11.3 0.0 1.3 1 0 0 1 1 1 0 NADH ubiquinone oxidoreductase, 20 Kd subunit EBP PF05241.12 CBZ25210.1 - 4.7e-18 65.3 1.3 5.9e-18 64.9 1.3 1.1 1 0 0 1 1 1 1 Emopamil binding protein 2OG-FeII_Oxy_2 PF13532.6 CBZ25211.1 - 1e-57 195.5 0.1 1.3e-57 195.2 0.1 1.1 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily SpvB PF03534.13 CBZ25211.1 - 0.023 13.9 0.3 5 6.2 0.1 2.1 2 0 0 2 2 2 0 Salmonella virulence plasmid 65kDa B protein Tektin PF03148.14 CBZ25213.1 - 0.033 13.0 1.9 0.046 12.5 1.9 1.1 1 0 0 1 1 1 0 Tektin family SKA1 PF07160.12 CBZ25213.1 - 0.056 13.3 0.1 0.084 12.7 0.1 1.2 1 0 0 1 1 1 0 Spindle and kinetochore-associated protein 1 End3 PF12761.7 CBZ25213.1 - 0.22 11.6 1.4 0.33 11.1 1.4 1.2 1 0 0 1 1 1 0 Actin cytoskeleton-regulatory complex protein END3 TTL PF03133.15 CBZ25214.1 - 1.2e-76 257.7 0.0 1.2e-75 254.4 0.0 2.2 1 1 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 CBZ25214.1 - 6.7e-06 25.5 0.0 0.042 13.1 0.0 2.5 2 0 0 2 2 2 2 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 CBZ25214.1 - 1.5e-05 24.4 0.0 0.034 13.4 0.0 2.2 2 0 0 2 2 2 2 Sugar-transfer associated ATP-grasp XRN_N PF03159.18 CBZ25215.1 - 7.6e-23 81.2 0.1 1.6e-18 67.0 0.0 3.6 2 1 0 2 2 2 2 XRN 5'-3' exonuclease N-terminus Pyridoxal_deC PF00282.19 CBZ25218.1 - 4.2e-17 61.9 0.1 1.3e-12 47.2 0.0 2.4 2 0 0 2 2 2 2 Pyridoxal-dependent decarboxylase conserved domain Dehydrin PF00257.19 CBZ25219.1 - 1.3 9.6 7.8 2 8.9 7.2 1.7 1 1 1 2 2 2 0 Dehydrin GHMP_kinases_N PF00288.26 CBZ25220.1 - 4.7e-06 26.8 2.2 1.4e-05 25.3 0.0 2.8 2 2 1 3 3 3 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 CBZ25220.1 - 0.0006 20.1 0.0 0.0036 17.6 0.0 2.4 2 0 0 2 2 2 1 GHMP kinases C terminal Fucokinase PF07959.12 CBZ25221.1 - 4.7e-12 45.6 0.0 2.7e-11 43.1 0.0 1.8 1 1 0 1 1 1 1 L-fucokinase Ribosomal_L21e PF01157.18 CBZ25223.1 - 1.3e-40 137.3 3.1 2.1e-40 136.7 3.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L21e TMEM192 PF14802.6 CBZ25224.1 - 0.59 9.2 4.9 0.79 8.8 4.9 1.4 1 0 0 1 1 1 0 TMEM192 family Fucokinase PF07959.12 CBZ25225.1 - 1.2e-12 47.5 0.0 3.6e-10 39.3 0.0 2.6 2 1 1 3 3 3 2 L-fucokinase GHMP_kinases_N PF00288.26 CBZ25225.1 - 4.3e-05 23.7 0.0 4.3e-05 23.7 0.0 2.8 3 1 0 3 3 3 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 CBZ25225.1 - 0.0031 17.8 0.2 0.012 15.9 0.0 2.2 2 0 0 2 2 2 1 GHMP kinases C terminal Amastin PF07344.11 CBZ25227.1 - 0.00088 19.1 15.2 0.00088 19.1 15.2 2.4 2 1 0 2 2 2 1 Amastin surface glycoprotein BaxI_1 PF12811.7 CBZ25227.1 - 0.55 9.8 13.5 0.019 14.5 7.2 1.8 2 1 1 3 3 3 0 Bax inhibitor 1 like EphA2_TM PF14575.6 CBZ25227.1 - 5.2 8.0 9.8 7.1 7.6 0.0 3.8 4 0 0 4 4 4 0 Ephrin type-A receptor 2 transmembrane domain Iso_dh PF00180.20 CBZ25229.1 - 0.091 11.9 1.6 1.6 7.8 0.2 2.1 2 0 0 2 2 2 0 Isocitrate/isopropylmalate dehydrogenase Uteroglobin PF01099.17 CBZ25229.1 - 0.18 12.2 1.0 0.45 10.9 0.3 2.0 2 0 0 2 2 2 0 Uteroglobin family DHO_dh PF01180.21 CBZ25230.1 - 2.5e-68 230.5 0.0 2.8e-68 230.3 0.0 1.0 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase FMN_dh PF01070.18 CBZ25230.1 - 0.045 12.8 0.0 0.089 11.8 0.0 1.4 1 0 0 1 1 1 0 FMN-dependent dehydrogenase PcrB PF01884.17 CBZ25230.1 - 0.14 11.6 0.0 0.23 10.9 0.0 1.3 1 0 0 1 1 1 0 PcrB family OTCace_N PF02729.21 CBZ25231.1 - 4.7e-40 137.0 0.3 7.1e-40 136.4 0.3 1.3 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain OTCace PF00185.24 CBZ25231.1 - 3.4e-33 115.0 0.0 1e-31 110.1 0.0 2.0 2 0 0 2 2 2 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain DUF3653 PF12375.8 CBZ25231.1 - 0.12 12.5 0.0 0.32 11.1 0.0 1.6 1 0 0 1 1 1 0 Phage protein OMPdecase PF00215.24 CBZ25232.1 - 4.5e-35 121.3 0.0 6.7e-35 120.7 0.0 1.3 1 0 0 1 1 1 1 Orotidine 5'-phosphate decarboxylase / HUMPS family Pribosyltran PF00156.27 CBZ25232.1 - 2.4e-18 66.2 0.2 5.2e-18 65.1 0.2 1.5 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.6 CBZ25232.1 - 0.00074 19.0 0.0 0.0014 18.1 0.0 1.4 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase PRTase_2 PF15609.6 CBZ25232.1 - 0.001 18.6 0.0 0.0019 17.7 0.0 1.5 1 0 0 1 1 1 1 Phosphoribosyl transferase AAA_18 PF13238.6 CBZ25233.1 - 0.018 15.6 0.0 0.087 13.4 0.0 2.1 2 0 0 2 2 2 0 AAA domain PRK PF00485.18 CBZ25233.1 - 0.1 12.3 0.0 0.22 11.3 0.0 1.5 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family Histone PF00125.24 CBZ25234.1 - 2.2e-41 141.3 5.9 2.4e-41 141.1 5.9 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 CBZ25234.1 - 1e-05 25.7 0.2 1e-05 25.7 0.2 1.7 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-S PF15630.6 CBZ25234.1 - 6e-05 23.3 0.0 0.00011 22.5 0.0 1.3 1 0 0 1 1 1 1 CENP-S protein CENP-T_C PF15511.6 CBZ25234.1 - 0.00012 22.1 0.1 0.00023 21.3 0.1 1.4 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold Bromo_TP PF07524.13 CBZ25234.1 - 0.044 13.8 0.0 0.069 13.2 0.0 1.2 1 0 0 1 1 1 0 Bromodomain associated TFIID-31kDa PF02291.15 CBZ25234.1 - 0.059 13.4 0.1 0.082 13.0 0.1 1.2 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Mitochondr_Som1 PF11093.8 CBZ25234.1 - 0.066 13.2 0.1 0.14 12.2 0.1 1.6 1 1 0 1 1 1 0 Mitochondrial export protein Som1 Histone PF00125.24 CBZ25235.1 - 2.2e-41 141.3 5.9 2.4e-41 141.1 5.9 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 CBZ25235.1 - 1e-05 25.7 0.2 1e-05 25.7 0.2 1.7 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-S PF15630.6 CBZ25235.1 - 6e-05 23.3 0.0 0.00011 22.5 0.0 1.3 1 0 0 1 1 1 1 CENP-S protein CENP-T_C PF15511.6 CBZ25235.1 - 0.00012 22.1 0.1 0.00023 21.3 0.1 1.4 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold Bromo_TP PF07524.13 CBZ25235.1 - 0.044 13.8 0.0 0.069 13.2 0.0 1.2 1 0 0 1 1 1 0 Bromodomain associated TFIID-31kDa PF02291.15 CBZ25235.1 - 0.059 13.4 0.1 0.082 13.0 0.1 1.2 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Mitochondr_Som1 PF11093.8 CBZ25235.1 - 0.066 13.2 0.1 0.14 12.2 0.1 1.6 1 1 0 1 1 1 0 Mitochondrial export protein Som1 Amidohydro_1 PF01979.20 CBZ25236.1 - 5.5e-08 32.5 0.8 7.6e-08 32.0 0.8 1.3 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_2 PF04909.14 CBZ25236.1 - 0.088 12.6 1.2 8.4 6.1 0.8 2.7 2 1 0 2 2 2 0 Amidohydrolase TatD_DNase PF01026.21 CBZ25236.1 - 0.1 12.0 4.2 0.16 11.3 2.8 2.0 2 1 0 2 2 2 0 TatD related DNase CPSase_L_D2 PF02786.17 CBZ25237.1 - 4.4e-102 340.0 0.4 1.3e-76 256.8 0.1 2.3 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_sm_chain PF00988.22 CBZ25237.1 - 5.7e-45 152.3 0.0 1.3e-44 151.1 0.0 1.7 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain GATase PF00117.28 CBZ25237.1 - 8.6e-42 143.1 0.0 2.1e-41 141.8 0.0 1.7 1 0 0 1 1 1 1 Glutamine amidotransferase class-I CPSase_L_D3 PF02787.19 CBZ25237.1 - 1.6e-31 109.2 0.0 3.7e-31 108.0 0.0 1.7 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain ATP-grasp PF02222.22 CBZ25237.1 - 5.2e-22 78.2 0.2 5.7e-13 48.8 0.0 2.4 2 0 0 2 2 2 2 ATP-grasp domain Arginosuc_synth PF00764.19 CBZ25237.1 - 4.9e-13 49.1 0.0 1.3e-12 47.8 0.0 1.6 1 0 0 1 1 1 1 Arginosuccinate synthase Dala_Dala_lig_C PF07478.13 CBZ25237.1 - 9e-13 48.2 0.8 1.9e-06 27.6 0.0 2.5 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus ATPgrasp_Ter PF15632.6 CBZ25237.1 - 5.9e-11 42.2 0.0 8.9e-06 25.5 0.0 2.7 2 1 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon Peptidase_C26 PF07722.13 CBZ25237.1 - 6.4e-08 32.6 0.3 4.5e-06 26.6 0.3 2.5 1 1 0 1 1 1 1 Peptidase C26 MGS PF02142.22 CBZ25237.1 - 2.5e-07 30.8 0.0 1.2e-06 28.6 0.0 2.3 2 0 0 2 2 1 1 MGS-like domain ATP-grasp_3 PF02655.14 CBZ25237.1 - 1.6e-05 25.0 0.2 0.00071 19.7 0.0 2.6 2 1 0 2 2 2 1 ATP-grasp domain GARS_A PF01071.19 CBZ25237.1 - 3.5e-05 23.7 0.4 0.11 12.2 0.0 3.3 2 1 0 2 2 2 2 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain DJ-1_PfpI PF01965.24 CBZ25237.1 - 0.00068 19.5 0.1 0.0068 16.2 0.0 2.7 3 0 0 3 3 3 1 DJ-1/PfpI family TrkA_N PF02254.18 CBZ25237.1 - 0.0043 17.3 0.0 0.045 14.0 0.0 2.7 2 0 0 2 2 2 1 TrkA-N domain GSH-S_ATP PF02955.16 CBZ25237.1 - 0.0059 16.0 0.0 0.016 14.6 0.0 1.7 1 0 0 1 1 1 1 Prokaryotic glutathione synthetase, ATP-grasp domain GSP_synth PF03738.14 CBZ25237.1 - 0.074 12.2 0.0 0.13 11.4 0.0 1.3 1 0 0 1 1 1 0 Glutathionylspermidine synthase preATP-grasp Histone PF00125.24 CBZ25238.1 - 2.2e-41 141.3 5.9 2.4e-41 141.1 5.9 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 CBZ25238.1 - 1e-05 25.7 0.2 1e-05 25.7 0.2 1.7 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-S PF15630.6 CBZ25238.1 - 6e-05 23.3 0.0 0.00011 22.5 0.0 1.3 1 0 0 1 1 1 1 CENP-S protein CENP-T_C PF15511.6 CBZ25238.1 - 0.00012 22.1 0.1 0.00023 21.3 0.1 1.4 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold Bromo_TP PF07524.13 CBZ25238.1 - 0.044 13.8 0.0 0.069 13.2 0.0 1.2 1 0 0 1 1 1 0 Bromodomain associated TFIID-31kDa PF02291.15 CBZ25238.1 - 0.059 13.4 0.1 0.082 13.0 0.1 1.2 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Mitochondr_Som1 PF11093.8 CBZ25238.1 - 0.066 13.2 0.1 0.14 12.2 0.1 1.6 1 1 0 1 1 1 0 Mitochondrial export protein Som1 Histone PF00125.24 CBZ25239.1 - 2.2e-41 141.3 5.9 2.4e-41 141.1 5.9 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 CBZ25239.1 - 1e-05 25.7 0.2 1e-05 25.7 0.2 1.7 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-S PF15630.6 CBZ25239.1 - 6e-05 23.3 0.0 0.00011 22.5 0.0 1.3 1 0 0 1 1 1 1 CENP-S protein CENP-T_C PF15511.6 CBZ25239.1 - 0.00012 22.1 0.1 0.00023 21.3 0.1 1.4 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold Bromo_TP PF07524.13 CBZ25239.1 - 0.044 13.8 0.0 0.069 13.2 0.0 1.2 1 0 0 1 1 1 0 Bromodomain associated TFIID-31kDa PF02291.15 CBZ25239.1 - 0.059 13.4 0.1 0.082 13.0 0.1 1.2 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Mitochondr_Som1 PF11093.8 CBZ25239.1 - 0.066 13.2 0.1 0.14 12.2 0.1 1.6 1 1 0 1 1 1 0 Mitochondrial export protein Som1 TP6A_N PF04406.14 CBZ25241.1 - 6.5e-11 42.1 1.4 6.5e-11 42.1 1.4 1.9 2 0 0 2 2 2 1 Type IIB DNA topoisomerase DUF2399 PF09664.10 CBZ25241.1 - 0.041 13.8 0.0 0.1 12.5 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function C-terminus (DUF2399) RRM_1 PF00076.22 CBZ25242.1 - 1.7e-13 50.2 0.0 3.1e-13 49.3 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Pro_isomerase PF00160.21 CBZ25242.1 - 4.1e-07 30.4 0.0 0.02 15.1 0.0 2.4 2 0 0 2 2 2 2 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD zf-rbx1 PF12678.7 CBZ25243.1 - 8.8e-17 61.1 12.6 1.2e-16 60.7 12.6 1.2 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 CBZ25243.1 - 9.9e-15 54.4 7.3 1.2e-14 54.1 7.3 1.2 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_2 PF13639.6 CBZ25243.1 - 8e-09 35.7 15.9 9.4e-07 29.1 16.3 2.2 1 1 1 2 2 2 1 Ring finger domain Prok-RING_4 PF14447.6 CBZ25243.1 - 2.5e-06 27.3 11.1 3.9e-05 23.4 7.3 2.3 2 1 0 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 CBZ25243.1 - 2.7e-05 24.0 13.2 0.00011 22.1 9.0 2.2 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 CBZ25243.1 - 0.00017 21.5 12.4 0.0049 16.9 12.4 2.7 1 1 0 1 1 1 1 RING-type zinc-finger zf-RING_6 PF14835.6 CBZ25243.1 - 0.00022 21.1 4.9 0.00022 21.1 4.9 1.7 1 1 1 2 2 2 1 zf-RING of BARD1-type protein zf-C3HC4_2 PF13923.6 CBZ25243.1 - 0.0007 19.4 16.3 0.0059 16.4 11.5 2.4 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 CBZ25243.1 - 0.0016 18.3 13.8 0.01 15.7 8.5 2.3 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CBZ25243.1 - 0.0043 16.9 13.2 0.021 14.7 13.2 2.1 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) FANCL_C PF11793.8 CBZ25243.1 - 0.013 15.7 13.7 0.04 14.1 3.9 3.1 1 1 2 3 3 3 0 FANCL C-terminal domain Zn-C2H2_12 PF18112.1 CBZ25243.1 - 0.028 14.9 6.4 1.6 9.3 0.0 3.3 3 0 0 3 3 3 0 Autophagy receptor zinc finger-C2H2 domain Zn_ribbon_17 PF17120.5 CBZ25243.1 - 0.033 13.8 14.5 0.064 12.9 13.9 1.9 1 1 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-Di19 PF05605.12 CBZ25243.1 - 0.076 13.3 10.3 0.061 13.6 3.4 2.3 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding tRNA-synt_1g PF09334.11 CBZ25243.1 - 0.2 10.3 3.1 0.77 8.4 0.6 2.0 1 1 1 2 2 2 0 tRNA synthetases class I (M) zf-RING_4 PF14570.6 CBZ25243.1 - 0.23 11.3 9.1 7.7 6.4 6.8 2.7 2 1 0 2 2 2 0 RING/Ubox like zinc-binding domain DUF1272 PF06906.11 CBZ25243.1 - 0.34 11.0 9.9 5.8 7.1 9.9 2.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1272) zf-RING_11 PF17123.5 CBZ25243.1 - 0.43 10.4 14.6 11 5.9 14.6 2.4 1 1 0 1 1 1 0 RING-like zinc finger Rtf2 PF04641.12 CBZ25243.1 - 0.56 9.5 2.6 0.29 10.4 0.3 1.6 1 1 0 1 1 1 0 Rtf2 RING-finger zf-C3H2C3 PF17122.5 CBZ25243.1 - 2.5 8.2 14.7 0.65 10.1 9.3 2.2 2 0 0 2 2 2 0 Zinc-finger zf-Nse PF11789.8 CBZ25243.1 - 2.8 7.8 8.5 11 5.9 8.5 1.9 1 1 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit HMMR_N PF15905.5 CBZ25244.1 - 0.0005 19.6 32.8 0.0005 19.6 32.8 4.2 2 2 2 4 4 4 2 Hyaluronan mediated motility receptor N-terminal DUF1738 PF08401.11 CBZ25245.1 - 0.00014 22.0 0.0 0.047 13.8 0.0 3.0 3 0 0 3 3 3 2 Domain of unknown function (DUF1738) Exo_endo_phos PF03372.23 CBZ25246.1 - 1.3e-15 57.5 0.2 4.6e-15 55.8 0.2 1.8 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Pap_E4 PF02711.14 CBZ25246.1 - 1 10.4 5.0 1.9 9.5 5.0 1.5 1 0 0 1 1 1 0 E4 protein Mucin PF01456.17 CBZ25246.1 - 6.7 6.7 18.7 16 5.4 18.7 1.6 1 0 0 1 1 1 0 Mucin-like glycoprotein eIF2A PF08662.11 CBZ25247.1 - 9.8e-38 130.0 0.0 2.1e-34 119.1 0.0 3.1 2 1 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A LysM PF01476.20 CBZ25248.1 - 1.2e-08 34.8 0.0 0.00032 20.7 0.0 2.4 2 0 0 2 2 2 2 LysM domain Spc29 PF17082.5 CBZ25249.1 - 0.012 15.5 0.1 0.024 14.5 0.1 1.5 1 0 0 1 1 1 0 Spindle Pole Component 29 DUF1043 PF06295.12 CBZ25249.1 - 0.82 9.7 3.1 0.75 9.8 1.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1043) LRR_6 PF13516.6 CBZ25250.1 - 3.8e-09 35.9 17.4 0.7 10.1 0.1 6.7 6 0 0 6 6 6 6 Leucine Rich repeat LRR_4 PF12799.7 CBZ25250.1 - 2.4e-05 24.6 11.3 0.0017 18.7 0.3 4.5 5 0 0 5 5 5 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CBZ25250.1 - 0.0029 17.4 9.4 1.2 9.0 1.4 4.7 3 1 1 4 4 4 3 Leucine rich repeat LRR_1 PF00560.33 CBZ25250.1 - 0.059 13.9 11.7 34 5.5 0.2 5.6 6 0 0 6 6 6 0 Leucine Rich Repeat UCH PF00443.29 CBZ25251.1 - 5e-35 121.2 0.0 8.1e-35 120.5 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 CBZ25251.1 - 4.4e-17 62.7 0.0 6.9e-16 58.7 0.0 2.3 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase zf-RanBP PF00641.18 CBZ25251.1 - 0.0047 16.2 1.1 0.0047 16.2 1.1 2.6 2 0 0 2 2 2 1 Zn-finger in Ran binding protein and others FAD_binding_5 PF00941.21 CBZ25251.1 - 0.083 12.6 1.0 0.25 11.0 0.5 2.1 3 0 0 3 3 3 0 FAD binding domain in molybdopterin dehydrogenase Prok-RING_1 PF14446.6 CBZ25251.1 - 0.34 10.9 4.6 0.3 11.0 1.7 2.5 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 HAD PF12710.7 CBZ25253.1 - 0.29 11.5 2.6 1.6 9.1 0.0 2.9 3 0 0 3 3 3 0 haloacid dehalogenase-like hydrolase TAL_FSA PF00923.19 CBZ25254.1 - 2.1e-95 319.3 0.1 2.4e-95 319.2 0.1 1.0 1 0 0 1 1 1 1 Transaldolase/Fructose-6-phosphate aldolase SH3BGR PF04908.15 CBZ25255.1 - 0.0017 18.5 0.0 0.0034 17.5 0.0 1.5 1 0 0 1 1 1 1 SH3-binding, glutamic acid-rich protein VPS13 PF16908.5 CBZ25256.1 - 1.4e-29 103.6 0.0 3.3e-29 102.4 0.0 1.7 1 0 0 1 1 1 1 Vacuolar sorting-associated protein 13, N-terminal VPS13_C PF16909.5 CBZ25256.1 - 2.6e-21 76.2 0.2 5.5e-15 55.6 0.0 2.5 2 0 0 2 2 2 2 Vacuolar-sorting-associated 13 protein C-terminal Chorein_N PF12624.7 CBZ25256.1 - 3.9e-17 62.4 0.2 2.3e-10 40.6 0.2 2.8 2 0 0 2 2 2 2 N-terminal region of Chorein or VPS13 VPS13_mid_rpt PF16910.5 CBZ25256.1 - 7.4e-11 41.9 0.0 4.6e-10 39.3 0.0 2.2 2 0 0 2 2 2 1 Repeating coiled region of VPS13 SHR-BD PF06650.12 CBZ25256.1 - 1.8e-05 24.3 0.0 2.2 7.6 0.0 3.7 3 1 0 3 3 3 3 SHR-binding domain of vacuolar-sorting associated protein 13 Glyco_hydro_18 PF00704.28 CBZ25257.1 - 4e-52 177.9 0.0 4.8e-52 177.6 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Mem_trans PF03547.18 CBZ25258.1 - 3.7e-12 45.3 14.8 1.6e-09 36.7 0.0 3.5 3 1 0 3 3 3 2 Membrane transport protein BILBO1_N PF18281.1 CBZ25260.1 - 4.2e-05 23.9 0.0 0.0007 20.0 0.0 2.4 1 1 0 1 1 1 1 BILBO1 N-terminal domain EF-hand_1 PF00036.32 CBZ25260.1 - 0.037 13.6 0.0 0.073 12.7 0.0 1.4 1 0 0 1 1 1 0 EF hand Fe-S_biosyn PF01521.20 CBZ25261.1 - 2.3e-08 34.2 0.0 1.2e-07 31.9 0.0 2.0 1 1 0 1 1 1 1 Iron-sulphur cluster biosynthesis JAB PF01398.21 CBZ25263.1 - 8.6e-20 70.9 0.0 1.4e-19 70.2 0.0 1.3 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Prok-JAB PF14464.6 CBZ25263.1 - 0.0041 16.9 0.0 0.0091 15.8 0.0 1.6 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain Pkinase PF00069.25 CBZ25265.1 - 1.2e-32 113.4 0.0 2.4e-32 112.4 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ25265.1 - 3.5e-24 85.5 0.0 6e-24 84.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase zf-C2H2_4 PF13894.6 CBZ25265.1 - 0.52 11.3 1.9 1.6 9.8 1.9 1.9 1 0 0 1 1 1 0 C2H2-type zinc finger Nop52 PF05997.12 CBZ25267.1 - 1.1e-32 113.7 2.2 3.3e-27 95.7 1.1 3.4 3 0 0 3 3 3 3 Nucleolar protein,Nop52 EF-hand_7 PF13499.6 CBZ25269.1 - 0.17 12.4 0.0 2 9.0 0.0 2.7 2 0 0 2 2 2 0 EF-hand domain pair HalX PF08663.10 CBZ25269.1 - 7.3 7.0 6.9 2.4 8.5 1.4 2.7 2 0 0 2 2 2 0 HalX domain EF-hand_1 PF00036.32 CBZ25270.1 - 2.9e-10 38.9 2.0 9.1e-05 21.7 0.0 3.4 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.6 CBZ25270.1 - 3.1e-10 39.1 0.7 0.00039 20.1 0.1 3.3 3 0 0 3 3 3 2 EF-hand domain EF-hand_7 PF13499.6 CBZ25270.1 - 7.2e-08 32.8 0.0 2.8e-07 30.9 0.0 2.0 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_5 PF13202.6 CBZ25270.1 - 1.8e-06 27.1 1.1 3.1e-05 23.3 0.1 2.9 2 1 0 2 2 2 1 EF hand EF-hand_8 PF13833.6 CBZ25270.1 - 2.5e-06 27.2 3.0 4.5e-05 23.2 0.0 2.7 2 1 1 3 3 3 2 EF-hand domain pair SPARC_Ca_bdg PF10591.9 CBZ25270.1 - 0.038 14.3 0.0 0.071 13.4 0.0 1.5 1 1 0 1 1 1 0 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_6 PF13405.6 CBZ25271.1 - 3.3e-13 48.4 1.0 0.00055 19.6 0.1 4.2 4 0 0 4 4 4 3 EF-hand domain EF-hand_7 PF13499.6 CBZ25271.1 - 8.4e-11 42.2 0.2 4.6e-07 30.2 0.0 2.7 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_1 PF00036.32 CBZ25271.1 - 1.8e-09 36.4 4.0 0.00013 21.3 0.0 3.8 4 0 0 4 4 4 2 EF hand EF-hand_5 PF13202.6 CBZ25271.1 - 1.2e-06 27.7 0.7 4.3e-05 22.8 0.1 3.4 3 1 0 3 3 3 1 EF hand EF-hand_8 PF13833.6 CBZ25271.1 - 9.9e-06 25.3 5.5 7e-05 22.6 0.0 3.4 3 1 1 4 4 4 2 EF-hand domain pair SPARC_Ca_bdg PF10591.9 CBZ25271.1 - 0.028 14.7 0.2 0.1 12.9 0.0 2.0 1 1 1 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region Snf7 PF03357.21 CBZ25272.1 - 1.2e-24 86.9 8.8 1.2e-24 86.9 8.8 1.5 2 0 0 2 2 2 1 Snf7 DUF3801 PF12687.7 CBZ25272.1 - 0.64 10.1 6.4 0.16 12.0 2.9 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF3801) Dynein_light PF01221.18 CBZ25273.1 - 1e-24 86.6 0.7 1.2e-24 86.4 0.7 1.1 1 0 0 1 1 1 1 Dynein light chain type 1 YsaB PF13983.6 CBZ25273.1 - 0.14 12.4 0.0 0.2 11.9 0.0 1.4 1 0 0 1 1 1 0 YsaB-like lipoprotein Glycos_transf_1 PF00534.20 CBZ25274.1 - 1.7e-28 99.3 0.0 2.8e-28 98.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 CBZ25274.1 - 8e-19 68.4 0.0 1.7e-18 67.3 0.0 1.5 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 CBZ25274.1 - 0.00084 19.4 0.0 0.0015 18.5 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_1_2 PF13524.6 CBZ25274.1 - 0.0013 19.1 0.0 0.0059 17.0 0.0 2.0 2 0 0 2 2 2 1 Glycosyl transferases group 1 Methyltransf_23 PF13489.6 CBZ25275.1 - 1.1e-16 61.1 0.0 1.9e-15 57.1 0.0 2.3 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 CBZ25275.1 - 6.2e-14 52.4 0.0 8.9e-13 48.7 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 CBZ25275.1 - 1.2e-11 44.5 0.0 1.7e-10 40.7 0.0 2.2 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.6 CBZ25275.1 - 6.2e-10 39.7 0.0 2.5e-07 31.3 0.0 2.6 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_31 PF13847.6 CBZ25275.1 - 1.9e-06 27.7 0.0 4e-05 23.5 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 CBZ25275.1 - 2.4e-06 28.2 0.0 0.00086 20.0 0.0 2.7 2 0 0 2 2 2 1 Methyltransferase domain Spc7 PF08317.11 CBZ25277.1 - 0.0035 16.3 11.8 0.0035 16.3 11.8 6.6 1 1 7 8 8 8 5 Spc7 kinetochore protein DHR10 PF18595.1 CBZ25277.1 - 0.005 16.9 5.8 0.005 16.9 5.8 11.5 1 1 9 11 11 11 1 Designed helical repeat protein 10 domain UPF0242 PF06785.11 CBZ25277.1 - 0.0066 16.6 4.4 0.0066 16.6 4.4 7.8 1 1 5 7 7 7 3 Uncharacterised protein family (UPF0242) N-terminus DUF1664 PF07889.12 CBZ25277.1 - 0.082 12.9 76.2 0.25 11.4 7.3 8.6 2 2 5 8 8 8 0 Protein of unknown function (DUF1664) DUF4041 PF13250.6 CBZ25277.1 - 0.09 12.7 2.8 3.7 7.5 0.1 4.2 4 0 0 4 4 4 0 Domain of unknown function (DUF4041) Pkinase PF00069.25 CBZ25278.1 - 1.4e-58 198.4 0.0 9.7e-34 116.9 0.0 2.8 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ25278.1 - 4.3e-28 98.3 0.0 4.4e-19 68.8 0.0 3.0 3 0 0 3 3 3 2 Protein tyrosine kinase PNP_UDP_1 PF01048.20 CBZ25278.1 - 0.026 13.8 0.0 0.05 12.8 0.0 1.4 1 0 0 1 1 1 0 Phosphorylase superfamily Kdo PF06293.14 CBZ25278.1 - 0.14 11.4 0.0 0.28 10.5 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Stealth_CR2 PF11380.8 CBZ25279.1 - 8.1e-17 61.4 0.1 1.5e-14 54.1 0.1 2.6 1 1 0 1 1 1 1 Stealth protein CR2, conserved region 2 Stealth_CR3 PF17102.5 CBZ25279.1 - 1.6e-11 43.9 3.1 1.6e-11 43.9 3.1 2.0 2 0 0 2 2 2 1 Stealth protein CR3, conserved region 3 Stealth_CR1 PF17101.5 CBZ25279.1 - 0.54 10.0 2.0 14 5.6 0.0 3.2 3 0 0 3 3 3 0 Stealth protein CR1, conserved region 1 Stealth_CR2 PF11380.8 CBZ25280.1 - 4.8e-17 62.1 0.1 6.6e-15 55.2 0.1 2.4 1 1 0 1 1 1 1 Stealth protein CR2, conserved region 2 Stealth_CR3 PF17102.5 CBZ25280.1 - 6.5e-12 45.2 4.2 6.5e-12 45.2 4.2 2.5 3 0 0 3 3 3 1 Stealth protein CR3, conserved region 3 Stealth_CR2 PF11380.8 CBZ25282.1 - 9.9e-17 61.1 0.1 1.7e-14 53.9 0.1 2.5 1 1 0 1 1 1 1 Stealth protein CR2, conserved region 2 Stealth_CR3 PF17102.5 CBZ25282.1 - 1.8e-11 43.8 3.1 1.8e-11 43.8 3.1 2.0 2 0 0 2 2 2 1 Stealth protein CR3, conserved region 3 Stealth_CR1 PF17101.5 CBZ25282.1 - 0.68 9.7 2.0 15 5.4 0.0 3.2 3 0 0 3 3 3 0 Stealth protein CR1, conserved region 1 Stealth_CR2 PF11380.8 CBZ25283.1 - 6.4e-17 61.7 0.1 9.3e-15 54.7 0.1 2.4 1 1 0 1 1 1 1 Stealth protein CR2, conserved region 2 Stealth_CR3 PF17102.5 CBZ25283.1 - 6.2e-12 45.2 4.2 6.2e-12 45.2 4.2 1.9 2 0 0 2 2 2 1 Stealth protein CR3, conserved region 3 DUF5631 PF18645.1 CBZ25283.1 - 0.063 13.7 0.1 0.29 11.5 0.1 2.1 1 0 0 1 1 1 0 Family of unknown function (DUF5631) Stealth_CR2 PF11380.8 CBZ25284.1 - 4.9e-17 62.1 0.1 6.9e-15 55.2 0.1 2.5 1 1 0 1 1 1 1 Stealth protein CR2, conserved region 2 Stealth_CR3 PF17102.5 CBZ25284.1 - 6.2e-06 26.0 3.9 6.2e-06 26.0 3.9 2.2 3 0 0 3 3 3 1 Stealth protein CR3, conserved region 3 Stealth_CR2 PF11380.8 CBZ25285.1 - 1.3e-17 63.9 0.2 1.9e-15 57.0 0.2 2.5 1 1 0 1 1 1 1 Stealth protein CR2, conserved region 2 Stealth_CR3 PF17102.5 CBZ25285.1 - 6.1e-11 42.1 1.9 6.1e-11 42.1 1.9 2.1 2 0 0 2 2 2 1 Stealth protein CR3, conserved region 3 Ufm1 PF03671.14 CBZ25286.1 - 8e-35 118.8 0.1 9.7e-35 118.5 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin fold modifier 1 protein Polyketide_cyc PF03364.20 CBZ25290.1 - 0.012 15.8 0.7 0.012 15.8 0.7 2.0 2 0 0 2 2 2 0 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc PF03364.20 CBZ25291.1 - 8.6e-12 45.4 2.8 6.4e-11 42.6 2.8 2.2 1 1 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc PF03364.20 CBZ25292.1 - 1.1e-09 38.6 2.5 8.4e-09 35.7 2.5 2.1 1 1 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport tRNA_bind PF01588.20 CBZ25294.1 - 5e-23 81.0 0.0 8.1e-23 80.4 0.0 1.4 1 0 0 1 1 1 1 Putative tRNA binding domain WW PF00397.26 CBZ25295.1 - 5.1e-52 173.6 35.3 5.6e-14 51.9 1.6 5.4 5 0 0 5 5 5 5 WW domain DUF4585 PF15232.6 CBZ25295.1 - 0.63 10.1 5.5 49 4.1 0.0 5.2 6 0 0 6 6 6 0 Domain of unknown function (DUF4585) Tfb5 PF06331.12 CBZ25296.1 - 0.00079 19.4 0.0 0.0094 15.9 0.0 2.1 1 1 0 1 1 1 1 Transcription factor TFIIH complex subunit Tfb5 UvrD_C PF13361.6 CBZ25297.1 - 0.088 12.2 1.6 0.1 12.0 1.6 1.2 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain Ribosomal_L39 PF00832.20 CBZ25299.1 - 3.4e-18 65.0 15.4 3.8e-18 64.8 15.4 1.0 1 0 0 1 1 1 1 Ribosomal L39 protein Adap_comp_sub PF00928.21 CBZ25300.1 - 2.1e-13 50.2 0.0 3.8e-13 49.4 0.0 1.3 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 CBZ25300.1 - 0.00032 20.7 0.1 0.00058 19.8 0.1 1.4 1 0 0 1 1 1 1 Clathrin adaptor complex small chain AAA_25 PF13481.6 CBZ25300.1 - 0.12 11.9 0.0 0.2 11.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain RSN1_7TM PF02714.15 CBZ25301.1 - 5e-24 85.1 7.7 9.6e-24 84.1 7.7 1.5 1 0 0 1 1 1 1 Calcium-dependent channel, 7TM region, putative phosphate PHM7_cyt PF14703.6 CBZ25301.1 - 0.017 15.3 0.0 0.044 14.0 0.0 1.6 1 0 0 1 1 1 0 Cytosolic domain of 10TM putative phosphate transporter DUF4590 PF15257.6 CBZ25301.1 - 0.055 13.4 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4590) MRAP PF15183.6 CBZ25301.1 - 4.8 7.2 8.1 3.6 7.6 0.5 2.9 2 0 0 2 2 2 0 Melanocortin-2 receptor accessory protein family Pro_isomerase PF00160.21 CBZ25302.1 - 1.5e-29 103.3 0.0 2.2e-29 102.8 0.0 1.2 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD dsrm PF00035.26 CBZ25303.1 - 7.9e-06 26.5 0.1 0.57 10.9 0.0 4.5 4 0 0 4 4 4 2 Double-stranded RNA binding motif Cullin PF00888.22 CBZ25304.1 - 5.2e-38 131.1 0.0 1.1e-31 110.1 0.0 4.0 4 1 0 4 4 4 3 Cullin family Cullin_Nedd8 PF10557.9 CBZ25304.1 - 8.3e-16 57.8 0.0 1.4e-15 57.1 0.0 1.4 1 0 0 1 1 1 1 Cullin protein neddylation domain LSM PF01423.22 CBZ25307.1 - 0.00015 21.4 0.1 0.0007 19.2 0.1 2.0 1 1 0 1 1 1 1 LSM domain CIA30 PF08547.12 CBZ25310.1 - 0.1 12.6 0.0 0.12 12.4 0.0 1.1 1 0 0 1 1 1 0 Complex I intermediate-associated protein 30 (CIA30) DAGK_acc PF00609.19 CBZ25311.1 - 1.2e-20 74.4 0.0 3.5e-20 72.9 0.0 1.8 1 1 0 1 1 1 1 Diacylglycerol kinase accessory domain DAGK_cat PF00781.24 CBZ25311.1 - 2.5e-06 27.1 0.0 9.8e-06 25.2 0.0 2.1 1 1 0 1 1 1 1 Diacylglycerol kinase catalytic domain Cytochrom_C PF00034.21 CBZ25313.1 - 4.4e-11 43.8 0.0 5.5e-11 43.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome c Cytochrome_CBB3 PF13442.6 CBZ25313.1 - 4e-05 23.9 0.8 0.00026 21.2 0.8 2.0 1 1 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C PF00034.21 CBZ25314.1 - 4.4e-11 43.8 0.0 5.5e-11 43.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome c Cytochrome_CBB3 PF13442.6 CBZ25314.1 - 4e-05 23.9 0.8 0.00026 21.2 0.8 2.0 1 1 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III LRR_4 PF12799.7 CBZ25315.1 - 6.3e-20 70.9 33.1 0.0006 20.1 1.1 11.9 9 3 4 14 14 14 9 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CBZ25315.1 - 9.6e-09 34.9 36.2 1.6e-05 24.5 1.5 9.0 7 2 3 10 10 10 4 Leucine rich repeat LRR_9 PF14580.6 CBZ25315.1 - 3.2e-06 26.8 11.1 0.11 12.0 0.1 4.8 4 1 1 5 5 5 3 Leucine-rich repeat LRR_6 PF13516.6 CBZ25315.1 - 7.9e-05 22.4 26.5 40 4.6 0.0 12.3 13 0 0 13 13 13 1 Leucine Rich repeat RNA_pol_Rpb1_5 PF04998.17 CBZ25317.1 - 2.6e-58 197.6 0.0 8.1e-58 195.9 0.0 1.8 1 1 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.20 CBZ25317.1 - 8.6e-49 166.0 0.0 1.5e-48 165.2 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.18 CBZ25317.1 - 2.8e-30 105.3 0.0 6.3e-30 104.2 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.17 CBZ25317.1 - 1.4e-14 53.9 0.3 4.2e-14 52.4 0.3 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 RNA_pol_Rpb1_1 PF04997.12 CBZ25317.1 - 0.056 12.8 0.1 0.17 11.2 0.0 1.8 2 0 0 2 2 2 0 RNA polymerase Rpb1, domain 1 Amidase PF01425.21 CBZ25318.1 - 1.1e-58 199.3 0.0 7.9e-58 196.5 0.0 1.9 1 1 0 1 1 1 1 Amidase LSM PF01423.22 CBZ25319.1 - 4.7e-05 23.0 0.0 6.2e-05 22.6 0.0 1.1 1 0 0 1 1 1 1 LSM domain BPL_C PF02237.17 CBZ25319.1 - 0.021 14.7 0.1 0.032 14.1 0.1 1.3 1 0 0 1 1 1 0 Biotin protein ligase C terminal domain Arf PF00025.21 CBZ25320.1 - 2.3e-47 160.7 0.0 2.6e-47 160.5 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 CBZ25320.1 - 4.3e-10 39.9 0.0 6e-10 39.4 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 CBZ25320.1 - 4.7e-10 39.2 0.0 6e-10 38.8 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.27 CBZ25320.1 - 3.2e-09 36.6 0.2 3.2e-08 33.3 0.2 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Ras PF00071.22 CBZ25320.1 - 2.8e-08 33.6 0.0 3.2e-08 33.4 0.0 1.1 1 0 0 1 1 1 1 Ras family G-alpha PF00503.20 CBZ25320.1 - 2.4e-07 30.2 1.8 0.0034 16.6 0.3 2.7 1 1 1 2 2 2 2 G-protein alpha subunit MMR_HSR1 PF01926.23 CBZ25320.1 - 5.4e-07 29.7 0.0 7.5e-07 29.2 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 CBZ25320.1 - 2.5e-06 27.0 0.1 3.2e-06 26.7 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_22 PF13401.6 CBZ25320.1 - 0.00017 21.9 0.0 0.005 17.1 0.0 2.1 1 1 0 1 1 1 1 AAA domain FeoB_N PF02421.18 CBZ25320.1 - 0.00097 18.7 0.2 0.0025 17.4 0.2 1.7 1 1 0 1 1 1 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 CBZ25320.1 - 0.0065 16.4 0.0 3.7 7.4 0.0 2.1 2 0 0 2 2 2 2 RsgA GTPase cobW PF02492.19 CBZ25320.1 - 0.0085 15.7 0.0 2.7 7.5 0.0 2.1 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain AAA_18 PF13238.6 CBZ25320.1 - 0.024 15.2 0.0 0.041 14.4 0.0 1.6 1 1 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.18 CBZ25320.1 - 0.13 11.6 0.3 0.84 8.9 0.1 2.3 2 1 0 3 3 3 0 FtsK/SpoIIIE family Septin PF00735.18 CBZ25320.1 - 0.15 11.3 0.0 0.24 10.6 0.0 1.3 1 0 0 1 1 1 0 Septin OTU PF02338.19 CBZ25321.1 - 1.8e-13 51.1 0.0 3.2e-13 50.3 0.0 1.4 1 0 0 1 1 1 1 OTU-like cysteine protease Peptidase_C65 PF10275.9 CBZ25321.1 - 0.077 12.4 0.0 0.13 11.6 0.0 1.3 1 0 0 1 1 1 0 Peptidase C65 Otubain EMG1 PF03587.14 CBZ25322.1 - 1e-57 195.0 0.0 1.7e-57 194.3 0.0 1.3 1 1 0 1 1 1 1 EMG1/NEP1 methyltransferase HTH_18 PF12833.7 CBZ25322.1 - 0.052 13.8 0.1 6.3 7.2 0.0 2.4 2 0 0 2 2 2 0 Helix-turn-helix domain TRAPP PF04051.16 CBZ25323.1 - 6.2e-22 77.9 0.0 7.7e-22 77.6 0.0 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component FAM184 PF15665.5 CBZ25324.1 - 0.082 12.7 32.9 0.021 14.6 16.0 2.8 1 1 1 2 2 2 0 Family with sequence similarity 184, A and B IFP_35_N PF07334.13 CBZ25324.1 - 0.71 10.0 4.8 0.26 11.4 1.4 2.1 2 0 0 2 2 2 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus CENP-Q PF13094.6 CBZ25324.1 - 5.9 7.1 31.0 0.7 10.1 12.9 3.0 2 1 1 3 3 3 0 CENP-Q, a CENPA-CAD centromere complex subunit DUF4407 PF14362.6 CBZ25324.1 - 7 5.9 25.6 2.8 7.2 15.0 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) RloB PF13707.6 CBZ25325.1 - 0.025 14.8 1.3 0.042 14.0 1.3 1.4 1 0 0 1 1 1 0 RloB-like protein SIN1_PH PF16979.5 CBZ25325.1 - 0.59 10.4 5.7 1.4 9.2 5.7 1.7 1 1 0 1 1 1 0 SAPK-interacting protein 1 (Sin1), Pleckstrin-homology Flagellar_rod PF05149.12 CBZ25326.1 - 4.1e-57 193.8 5.2 5.6e-57 193.4 5.2 1.2 1 0 0 1 1 1 1 Paraflagellar rod protein TMF_TATA_bd PF12325.8 CBZ25326.1 - 3.5 7.9 15.5 0.38 11.0 6.3 2.6 2 1 0 2 2 2 0 TATA element modulatory factor 1 TATA binding Flagellar_rod PF05149.12 CBZ25327.1 - 2.8e-105 351.9 24.5 2.8e-105 351.9 24.5 2.2 2 0 0 2 2 2 1 Paraflagellar rod protein UPF0225 PF17775.1 CBZ25327.1 - 1 10.2 6.7 4.7 8.1 0.9 3.3 2 1 0 2 2 2 0 UPF0225 domain ING PF12998.7 CBZ25327.1 - 8.7 7.0 18.1 0.18 12.4 2.3 3.6 3 0 0 3 3 3 0 Inhibitor of growth proteins N-terminal histone-binding PAPS_reduct PF01507.19 CBZ25327.1 - 10 6.2 10.6 10 6.1 3.0 3.1 2 1 0 2 2 2 0 Phosphoadenosine phosphosulfate reductase family Kinesin PF00225.23 CBZ25330.1 - 4.9e-80 269.0 0.0 2e-77 260.4 0.0 3.9 2 0 0 2 2 2 1 Kinesin motor domain Laminin_I PF06008.14 CBZ25330.1 - 4.7e-39 134.7 478.3 0.03 14.1 17.9 24.7 2 1 18 22 22 21 19 Laminin Domain I Spc7 PF08317.11 CBZ25330.1 - 1.8e-37 128.9 503.3 0.0016 17.4 29.6 18.7 3 2 15 20 20 20 15 Spc7 kinetochore protein ApoB100_C PF12491.8 CBZ25330.1 - 1.1e-31 108.5 243.4 15 5.7 0.3 52.4 1 1 69 70 70 70 0 Apolipoprotein B100 C terminal Microtub_bd PF16796.5 CBZ25330.1 - 4.7e-21 75.3 0.0 2.8e-20 72.8 0.0 2.5 1 0 0 1 1 1 1 Microtubule binding COG2 PF06148.11 CBZ25330.1 - 9.1e-16 58.2 289.4 2.5 8.2 4.9 30.5 3 2 35 40 40 39 26 COG (conserved oligomeric Golgi) complex component, COG2 DUF3552 PF12072.8 CBZ25330.1 - 5.1e-15 55.4 447.0 1.9 7.8 14.7 29.3 1 1 28 31 31 26 8 Domain of unknown function (DUF3552) Laminin_II PF06009.12 CBZ25330.1 - 1.5e-14 54.2 383.7 1.7 8.6 13.1 27.1 3 1 28 31 31 31 14 Laminin Domain II KxDL PF10241.9 CBZ25330.1 - 5.2e-13 49.1 354.3 2.2 8.6 7.9 29.8 5 1 32 39 39 39 24 Uncharacterized conserved protein Herpes_BLLF1 PF05109.13 CBZ25330.1 - 5.6e-13 47.8 138.3 0.47 8.4 5.3 13.8 1 1 16 17 17 17 17 Herpes virus major outer envelope glycoprotein (BLLF1) IFT57 PF10498.9 CBZ25330.1 - 3.6e-10 39.4 402.1 0.55 9.1 20.6 19.9 2 1 16 20 20 20 14 Intra-flagellar transport protein 57 V-SNARE_C PF12352.8 CBZ25330.1 - 2.4e-09 37.4 217.6 6.8 7.1 2.4 29.4 2 1 21 30 30 30 9 Snare region anchored in the vesicle membrane C-terminus DUF3135 PF11333.8 CBZ25330.1 - 2.5e-05 24.4 2.4 0.27 11.5 0.2 3.1 2 0 0 2 2 2 2 Protein of unknown function (DUF3135) Tropomyosin PF00261.20 CBZ25330.1 - 0.026 13.9 539.1 0.14 11.5 38.1 15.6 2 2 16 18 18 15 0 Tropomyosin Cytotoxic PF09000.10 CBZ25330.1 - 0.16 12.3 0.8 34 4.9 0.1 2.7 2 0 0 2 2 2 0 Cytotoxic Exonuc_VII_L PF02601.15 CBZ25330.1 - 0.55 9.8 363.4 4.9 6.6 18.2 17.4 1 1 5 6 6 5 0 Exonuclease VII, large subunit L31 PF09784.9 CBZ25330.1 - 1.8 9.0 4.8 61 4.1 2.4 5.3 2 0 0 2 2 2 0 Mitochondrial ribosomal protein L31 PKcGMP_CC PF16808.5 CBZ25330.1 - 8.2 6.4 26.6 24 4.9 0.2 11.4 7 0 0 7 7 4 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Kinesin PF00225.23 CBZ25331.1 - 4.7e-78 262.4 0.0 4.7e-78 262.4 0.0 2.2 2 1 1 3 3 3 1 Kinesin motor domain Microtub_bd PF16796.5 CBZ25331.1 - 2e-21 76.5 0.0 8.7e-21 74.4 0.0 2.2 1 0 0 1 1 1 1 Microtubule binding Spc7 PF08317.11 CBZ25331.1 - 9.4e-10 37.9 114.5 0.0015 17.5 30.1 6.1 2 1 4 6 6 6 4 Spc7 kinetochore protein ApoB100_C PF12491.8 CBZ25331.1 - 1.8e-08 34.2 41.1 7.9 6.5 0.2 11.1 2 1 14 16 16 16 12 Apolipoprotein B100 C terminal Laminin_I PF06008.14 CBZ25331.1 - 1.4e-05 25.0 108.3 0.015 15.1 16.1 7.0 2 1 6 8 8 7 6 Laminin Domain I Herpes_BLLF1 PF05109.13 CBZ25331.1 - 0.0023 16.0 17.3 0.38 8.7 6.4 2.6 1 1 1 2 2 2 2 Herpes virus major outer envelope glycoprotein (BLLF1) Laminin_II PF06009.12 CBZ25331.1 - 0.0027 17.7 83.3 1.2 9.1 14.7 8.1 3 1 5 8 8 8 5 Laminin Domain II IFT57 PF10498.9 CBZ25331.1 - 0.0045 16.0 85.7 0.098 11.6 19.3 6.1 2 1 4 6 6 6 2 Intra-flagellar transport protein 57 V-SNARE_C PF12352.8 CBZ25331.1 - 0.008 16.4 38.4 4.3 7.7 1.5 7.5 3 1 5 8 8 8 5 Snare region anchored in the vesicle membrane C-terminus KxDL PF10241.9 CBZ25331.1 - 0.011 16.0 76.7 1 9.7 8.3 9.3 3 2 8 12 12 12 0 Uncharacterized conserved protein Filament PF00038.21 CBZ25331.1 - 0.03 13.9 107.2 0.036 13.6 24.8 5.7 2 1 4 6 6 6 0 Intermediate filament protein DUF5082 PF16888.5 CBZ25331.1 - 0.039 14.2 0.1 0.039 14.2 0.1 7.7 3 2 3 6 6 4 0 Domain of unknown function (DUF5082) COG2 PF06148.11 CBZ25331.1 - 0.084 13.0 69.8 0.64 10.1 1.7 9.0 2 1 8 10 10 10 0 COG (conserved oligomeric Golgi) complex component, COG2 ApoO PF09769.9 CBZ25331.1 - 0.43 10.6 42.5 29 4.6 1.0 8.4 4 1 4 8 8 8 0 Apolipoprotein O TMF_DNA_bd PF12329.8 CBZ25331.1 - 1.4 9.0 122.8 0.028 14.4 14.3 10.7 4 1 11 16 16 16 0 TATA element modulatory factor 1 DNA binding DUF1664 PF07889.12 CBZ25331.1 - 7.8 6.6 69.9 6.9 6.7 6.1 8.4 1 1 5 7 7 6 0 Protein of unknown function (DUF1664) FtsH_ext PF06480.15 CBZ25332.1 - 0.11 12.8 0.0 0.29 11.5 0.0 1.7 1 0 0 1 1 1 0 FtsH Extracellular Phage_term_sma PF07141.11 CBZ25333.1 - 0.084 12.6 0.1 0.13 12.0 0.1 1.3 1 0 0 1 1 1 0 Putative bacteriophage terminase small subunit OTT_1508_deam PF14441.6 CBZ25335.1 - 0.079 13.0 0.2 10 6.2 0.0 2.2 2 0 0 2 2 2 0 OTT_1508-like deaminase ERO1 PF04137.15 CBZ25337.1 - 3.6e-87 292.9 0.0 4.2e-87 292.6 0.0 1.0 1 0 0 1 1 1 1 Endoplasmic Reticulum Oxidoreductin 1 (ERO1) DNA_pol_B PF00136.21 CBZ25338.1 - 1.9e-126 422.4 0.0 2.5e-126 422.1 0.0 1.1 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.19 CBZ25338.1 - 3.7e-39 134.8 0.0 7.6e-39 133.8 0.0 1.5 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain zf-DNA_Pol PF08996.10 CBZ25338.1 - 0.0013 18.5 1.6 2 8.1 2.2 2.4 1 1 1 2 2 2 2 DNA Polymerase alpha zinc finger DNA_pol_B_2 PF03175.13 CBZ25338.1 - 0.028 13.3 0.0 0.05 12.5 0.0 1.3 1 0 0 1 1 1 0 DNA polymerase type B, organellar and viral WD40 PF00400.32 CBZ25339.1 - 1.4e-13 51.0 6.2 0.022 15.6 0.0 7.0 8 0 0 8 8 8 4 WD domain, G-beta repeat Asp4 PF16996.5 CBZ25339.1 - 0.079 12.8 0.3 0.22 11.3 0.3 1.7 1 0 0 1 1 1 0 Accessory secretory protein Sec Asp4 FAD_binding_8 PF08022.12 CBZ25340.1 - 0.097 12.8 0.0 0.23 11.5 0.0 1.6 1 0 0 1 1 1 0 FAD-binding domain Kinesin PF00225.23 CBZ25342.1 - 1.1e-70 238.2 0.0 1.9e-69 234.2 0.0 2.2 1 1 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 CBZ25342.1 - 9.8e-16 58.0 0.0 2.3e-15 56.8 0.0 1.6 1 1 0 1 1 1 1 Microtubule binding BST2 PF16716.5 CBZ25342.1 - 0.046 14.3 3.6 0.089 13.4 2.1 2.3 2 0 0 2 2 2 0 Bone marrow stromal antigen 2 DUF2470 PF10615.9 CBZ25342.1 - 0.073 13.7 0.1 0.25 12.0 0.1 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2470) AAA_24 PF13479.6 CBZ25342.1 - 0.11 12.2 0.0 0.22 11.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 CBZ25342.1 - 0.14 12.6 3.2 0.73 10.2 0.0 2.7 2 0 0 2 2 2 0 AAA ATPase domain AAA_22 PF13401.6 CBZ25342.1 - 0.87 9.9 4.8 9 6.6 0.2 2.6 2 0 0 2 2 2 0 AAA domain RRM_1 PF00076.22 CBZ25343.1 - 2.1e-13 49.9 0.0 3.1e-13 49.3 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) MIF4G PF02854.19 CBZ25344.1 - 1.2e-30 106.8 3.7 1.7e-30 106.2 3.7 1.3 1 0 0 1 1 1 1 MIF4G domain DUF5388 PF17363.2 CBZ25344.1 - 0.041 14.1 0.2 16 5.8 0.0 2.7 2 0 0 2 2 2 0 Family of unknown function (DUF5388) DUF2721 PF11026.8 CBZ25344.1 - 0.13 12.2 0.2 0.28 11.1 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2721) Band_7 PF01145.25 CBZ25345.1 - 1.7e-23 83.5 2.0 2.9e-23 82.8 2.0 1.4 1 0 0 1 1 1 1 SPFH domain / Band 7 family YdfA_immunity PF12127.8 CBZ25345.1 - 5.6e-05 22.4 1.3 7.1e-05 22.0 1.3 1.1 1 0 0 1 1 1 1 SigmaW regulon antibacterial WD40 PF00400.32 CBZ25346.1 - 1.3 10.0 6.6 5.2 8.1 0.0 3.8 3 0 0 3 3 3 0 WD domain, G-beta repeat Nop PF01798.18 CBZ25347.1 - 1.5e-13 50.7 3.3 2.2e-13 50.2 0.4 2.1 2 0 0 2 2 2 1 snoRNA binding domain, fibrillarin Prp31_C PF09785.9 CBZ25347.1 - 0.04 14.8 4.0 0.04 14.8 4.0 2.0 2 0 0 2 2 2 0 Prp31 C terminal domain XAP5 PF04921.14 CBZ25347.1 - 6.7 6.4 9.3 3.1 7.6 2.1 2.4 1 1 1 2 2 2 0 XAP5, circadian clock regulator eIF3_p135 PF12807.7 CBZ25348.1 - 0.0035 17.4 0.1 0.01 15.9 0.1 1.7 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit 135 IQ PF00612.27 CBZ25348.1 - 0.083 12.7 15.1 1.9 8.5 2.5 4.5 3 0 0 3 3 3 0 IQ calmodulin-binding motif TPR_12 PF13424.6 CBZ25348.1 - 0.28 11.5 16.3 14 6.1 0.0 6.9 6 1 1 7 7 7 0 Tetratricopeptide repeat TPR_2 PF07719.17 CBZ25348.1 - 2.8 8.3 9.5 93 3.5 0.0 6.2 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_14 PF13428.6 CBZ25348.1 - 6.6 7.8 20.2 35 5.6 0.1 8.1 8 1 1 9 9 9 0 Tetratricopeptide repeat CLU PF13236.6 CBZ25349.1 - 2.6e-10 40.5 0.0 1.3e-08 35.0 0.0 2.9 1 1 0 1 1 1 1 Clustered mitochondria eIF3_p135 PF12807.7 CBZ25349.1 - 0.0023 18.0 0.0 0.004 17.2 0.0 1.4 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit 135 Clathrin_H_link PF13838.6 CBZ25349.1 - 0.067 13.1 0.3 17 5.4 0.1 3.3 3 0 0 3 3 3 0 Clathrin-H-link CLU PF13236.6 CBZ25350.1 - 2.5e-09 37.3 0.0 9.6e-09 35.4 0.0 2.1 1 1 0 1 1 1 1 Clustered mitochondria TPR_2 PF07719.17 CBZ25350.1 - 0.018 15.1 0.0 0.49 10.6 0.0 3.5 2 0 0 2 2 2 0 Tetratricopeptide repeat eIF3_p135 PF12807.7 CBZ25350.1 - 0.03 14.4 2.5 0.031 14.3 0.1 2.2 2 0 0 2 2 2 0 Translation initiation factor eIF3 subunit 135 ANAPC3 PF12895.7 CBZ25351.1 - 0.0035 17.5 0.0 0.012 15.8 0.0 2.0 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 DUF3522 PF12036.8 CBZ25352.1 - 3.6e-42 144.8 16.9 4.3e-42 144.5 16.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3522) DUF3522 PF12036.8 CBZ25353.1 - 2.9e-40 138.6 5.1 2.9e-40 138.6 5.1 1.3 2 0 0 2 2 2 1 Protein of unknown function (DUF3522) zf-RING_2 PF13639.6 CBZ25354.1 - 1.6e-10 41.2 7.8 4.2e-10 39.8 7.8 1.8 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 CBZ25354.1 - 2.2e-08 34.0 5.0 4.6e-08 32.9 5.0 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 CBZ25354.1 - 9.5e-08 31.8 6.7 1.9e-07 30.8 6.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 CBZ25354.1 - 1.8e-07 30.9 8.1 3.4e-07 30.0 8.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 CBZ25354.1 - 4.1e-07 30.2 11.5 8.2e-07 29.2 9.0 2.6 2 1 0 2 2 2 1 RING-H2 zinc finger domain zf-RING_11 PF17123.5 CBZ25354.1 - 6.3e-07 29.0 4.5 6.3e-07 29.0 4.5 2.4 2 0 0 2 2 2 1 RING-like zinc finger zf-C3HC4_3 PF13920.6 CBZ25354.1 - 3.8e-06 26.6 3.5 1e-05 25.3 3.5 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CBZ25354.1 - 1.7e-05 24.7 4.9 4.6e-05 23.3 4.9 1.8 1 0 0 1 1 1 1 zinc-RING finger domain zf-ANAPC11 PF12861.7 CBZ25354.1 - 3.1e-05 24.0 1.3 3.1e-05 24.0 1.3 1.8 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_4 PF15227.6 CBZ25354.1 - 6.8e-05 22.9 6.3 0.00017 21.7 6.3 1.7 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 CBZ25354.1 - 0.0037 17.1 7.4 0.26 11.2 8.4 2.5 1 1 1 2 2 2 2 Prokaryotic RING finger family 4 zf-RING_6 PF14835.6 CBZ25354.1 - 0.031 14.1 2.3 0.14 12.1 2.0 2.1 1 1 1 2 2 2 0 zf-RING of BARD1-type protein FANCL_C PF11793.8 CBZ25354.1 - 0.19 11.9 8.5 2.8 8.2 5.8 3.0 1 1 1 2 2 2 0 FANCL C-terminal domain Zn_ribbon_17 PF17120.5 CBZ25354.1 - 0.25 11.0 5.5 0.86 9.3 5.5 2.0 1 1 0 1 1 1 0 Zinc-ribbon, C4HC2 type UBZ_FAAP20 PF15750.5 CBZ25354.1 - 0.55 10.2 5.3 0.81 9.7 0.1 2.7 2 0 0 2 2 2 0 Ubiquitin-binding zinc-finger zf-C3H2C3 PF17122.5 CBZ25354.1 - 1.2 9.3 7.0 6.9 6.8 6.9 2.4 1 1 1 2 2 2 0 Zinc-finger DnaJ PF00226.31 CBZ25355.1 - 4.7e-08 33.0 0.0 7.9e-08 32.3 0.0 1.3 1 0 0 1 1 1 1 DnaJ domain DUF4160 PF13711.6 CBZ25356.1 - 0.0063 16.8 0.6 0.014 15.7 0.6 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4160) Pkinase PF00069.25 CBZ25357.1 - 5.3e-68 229.2 0.0 7.9e-68 228.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ25357.1 - 1.3e-39 136.1 0.0 1.9e-39 135.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CBZ25357.1 - 5.5e-05 22.6 0.0 8.5e-05 22.0 0.0 1.2 1 0 0 1 1 1 1 Kinase-like LRR_6 PF13516.6 CBZ25357.1 - 0.00011 22.0 0.3 0.16 12.1 0.1 3.0 3 0 0 3 3 3 2 Leucine Rich repeat LRR_1 PF00560.33 CBZ25357.1 - 0.0027 18.0 0.2 8.6 7.4 0.0 3.2 2 0 0 2 2 2 2 Leucine Rich Repeat APH PF01636.23 CBZ25357.1 - 0.0038 17.2 0.0 1.5 8.7 0.0 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family LRR_4 PF12799.7 CBZ25357.1 - 0.013 15.9 0.5 0.04 14.4 0.4 2.0 1 1 0 1 1 1 0 Leucine Rich repeats (2 copies) RIO1 PF01163.22 CBZ25357.1 - 0.024 14.2 0.0 0.044 13.4 0.0 1.4 1 0 0 1 1 1 0 RIO1 family LRR_8 PF13855.6 CBZ25357.1 - 0.029 14.1 0.3 0.4 10.5 0.6 2.3 1 1 0 1 1 1 0 Leucine rich repeat Pkinase_fungal PF17667.1 CBZ25357.1 - 0.075 11.8 0.0 0.12 11.1 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Kdo PF06293.14 CBZ25357.1 - 0.094 12.1 0.0 0.16 11.3 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Arf PF00025.21 CBZ25358.1 - 2.7e-69 232.1 0.0 3.2e-69 231.8 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 CBZ25358.1 - 6.6e-13 48.9 0.0 1.1e-12 48.3 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 CBZ25358.1 - 4e-11 42.7 0.0 4.7e-11 42.5 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 CBZ25358.1 - 8.9e-11 41.5 0.1 6.2e-08 32.2 0.0 2.2 1 1 1 2 2 2 2 G-protein alpha subunit Ras PF00071.22 CBZ25358.1 - 2.3e-09 37.1 0.0 2.7e-09 36.9 0.0 1.1 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.12 CBZ25358.1 - 1.1e-08 34.7 0.0 1.4e-08 34.4 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 CBZ25358.1 - 1.6e-05 24.9 0.0 2.8e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 CBZ25358.1 - 0.015 14.9 0.6 0.078 12.5 0.6 2.0 1 1 0 1 1 1 0 Ferrous iron transport protein B GTP_EFTU PF00009.27 CBZ25359.1 - 2.1e-51 174.2 0.0 3.5e-51 173.5 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 CBZ25359.1 - 8.5e-41 138.8 0.1 2.7e-40 137.2 0.0 1.9 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 CBZ25359.1 - 2e-15 56.9 1.0 4.6e-15 55.8 0.3 2.0 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 CBZ25359.1 - 1.1e-05 25.5 0.1 0.00047 20.2 0.1 2.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D4 PF14578.6 CBZ25359.1 - 0.0049 16.7 1.0 0.011 15.6 0.2 2.0 2 0 0 2 2 2 1 Elongation factor Tu domain 4 FlpD PF02662.16 CBZ25359.1 - 0.005 16.8 0.1 0.013 15.5 0.0 1.7 2 0 0 2 2 2 1 Methyl-viologen-reducing hydrogenase, delta subunit SRPRB PF09439.10 CBZ25359.1 - 0.0051 16.3 0.1 0.024 14.1 0.1 2.3 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit Semialdhyde_dhC PF02774.18 CBZ25359.1 - 0.022 14.8 0.1 0.25 11.4 0.0 2.1 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, dimerisation domain GTP_EFTU PF00009.27 CBZ25360.1 - 2.1e-51 174.2 0.0 3.5e-51 173.5 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 CBZ25360.1 - 8.5e-41 138.8 0.1 2.7e-40 137.2 0.0 1.9 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 CBZ25360.1 - 2e-15 56.9 1.0 4.6e-15 55.8 0.3 2.0 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 CBZ25360.1 - 1.1e-05 25.5 0.1 0.00047 20.2 0.1 2.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D4 PF14578.6 CBZ25360.1 - 0.0049 16.7 1.0 0.011 15.6 0.2 2.0 2 0 0 2 2 2 1 Elongation factor Tu domain 4 FlpD PF02662.16 CBZ25360.1 - 0.005 16.8 0.1 0.013 15.5 0.0 1.7 2 0 0 2 2 2 1 Methyl-viologen-reducing hydrogenase, delta subunit SRPRB PF09439.10 CBZ25360.1 - 0.0051 16.3 0.1 0.024 14.1 0.1 2.3 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit Semialdhyde_dhC PF02774.18 CBZ25360.1 - 0.022 14.8 0.1 0.25 11.4 0.0 2.1 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, dimerisation domain GTP_EFTU PF00009.27 CBZ25361.1 - 2.1e-51 174.2 0.0 3.5e-51 173.5 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 CBZ25361.1 - 8.5e-41 138.8 0.1 2.7e-40 137.2 0.0 1.9 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 CBZ25361.1 - 2e-15 56.9 1.0 4.6e-15 55.8 0.3 2.0 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 CBZ25361.1 - 1.1e-05 25.5 0.1 0.00047 20.2 0.1 2.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D4 PF14578.6 CBZ25361.1 - 0.0049 16.7 1.0 0.011 15.6 0.2 2.0 2 0 0 2 2 2 1 Elongation factor Tu domain 4 FlpD PF02662.16 CBZ25361.1 - 0.005 16.8 0.1 0.013 15.5 0.0 1.7 2 0 0 2 2 2 1 Methyl-viologen-reducing hydrogenase, delta subunit SRPRB PF09439.10 CBZ25361.1 - 0.0051 16.3 0.1 0.024 14.1 0.1 2.3 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit Semialdhyde_dhC PF02774.18 CBZ25361.1 - 0.022 14.8 0.1 0.25 11.4 0.0 2.1 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, dimerisation domain GTP_EFTU PF00009.27 CBZ25362.1 - 2.3e-51 174.1 0.2 2.8e-51 173.8 0.2 1.0 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 CBZ25362.1 - 9.9e-07 28.8 0.0 0.00064 19.8 0.0 2.4 2 1 0 2 2 2 2 50S ribosome-binding GTPase SRPRB PF09439.10 CBZ25362.1 - 0.00087 18.8 0.3 0.0052 16.2 0.3 2.3 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit FlpD PF02662.16 CBZ25362.1 - 0.0019 18.2 0.0 0.0038 17.2 0.0 1.5 1 0 0 1 1 1 1 Methyl-viologen-reducing hydrogenase, delta subunit GTP_EFTU_D3 PF03143.17 CBZ25363.1 - 1.2e-41 141.5 0.1 5.6e-41 139.4 0.0 1.9 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 CBZ25363.1 - 7.4e-16 58.3 1.1 1.3e-15 57.5 0.3 1.8 2 0 0 2 2 2 1 Elongation factor Tu domain 2 GTP_EFTU_D4 PF14578.6 CBZ25363.1 - 0.0032 17.3 0.2 0.0032 17.3 0.2 1.7 2 0 0 2 2 2 1 Elongation factor Tu domain 4 Semialdhyde_dhC PF02774.18 CBZ25363.1 - 0.0077 16.3 0.2 0.048 13.7 0.1 2.1 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, dimerisation domain GTP_EFTU PF00009.27 CBZ25364.1 - 1.8e-51 174.5 0.0 2.8e-51 173.8 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 CBZ25364.1 - 1.7e-29 102.4 0.0 5.8e-29 100.7 0.0 1.9 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 CBZ25364.1 - 2.3e-15 56.8 1.0 4e-15 56.0 0.3 1.8 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 CBZ25364.1 - 8.6e-06 25.8 0.0 0.00039 20.5 0.0 2.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase FlpD PF02662.16 CBZ25364.1 - 0.0042 17.1 0.1 0.011 15.7 0.0 1.7 2 0 0 2 2 2 1 Methyl-viologen-reducing hydrogenase, delta subunit SRPRB PF09439.10 CBZ25364.1 - 0.0042 16.5 0.1 0.027 13.9 0.1 2.3 1 1 0 2 2 2 1 Signal recognition particle receptor beta subunit GTP_EFTU_D4 PF14578.6 CBZ25364.1 - 0.006 16.5 1.2 0.0095 15.8 0.2 1.8 2 0 0 2 2 2 1 Elongation factor Tu domain 4 GTP_EFTU PF00009.27 CBZ25365.1 - 4.7e-37 127.4 0.3 5e-37 127.3 0.3 1.0 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 CBZ25365.1 - 1.2e-06 28.6 0.1 8.5e-05 22.6 0.1 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 CBZ25365.1 - 0.0019 17.7 0.1 0.0079 15.6 0.0 1.9 1 1 1 2 2 2 1 Signal recognition particle receptor beta subunit Dynamin_N PF00350.23 CBZ25365.1 - 0.083 12.9 0.0 7.1 6.7 0.0 2.1 2 0 0 2 2 2 0 Dynamin family Guanylate_cyc PF00211.20 CBZ25366.1 - 2.1e-38 131.8 0.0 6.3e-38 130.2 0.0 1.8 2 0 0 2 2 2 1 Adenylate and Guanylate cyclase catalytic domain Mid2 PF04478.12 CBZ25366.1 - 0.058 13.2 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor Guanylate_cyc PF00211.20 CBZ25367.1 - 3.9e-36 124.4 0.0 6.9e-36 123.6 0.0 1.3 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain Peripla_BP_6 PF13458.6 CBZ25367.1 - 4.1e-08 33.3 3.7 8.3e-07 29.0 0.0 2.7 3 0 0 3 3 3 2 Periplasmic binding protein Guanylate_cyc PF00211.20 CBZ25368.1 - 7.7e-38 129.9 0.0 2e-37 128.6 0.0 1.6 2 0 0 2 2 2 1 Adenylate and Guanylate cyclase catalytic domain Guanylate_cyc PF00211.20 CBZ25369.1 - 1.1e-37 129.4 0.0 2e-37 128.6 0.0 1.4 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain Peripla_BP_6 PF13458.6 CBZ25370.1 - 0.00033 20.4 0.0 0.00041 20.1 0.0 1.1 1 0 0 1 1 1 1 Periplasmic binding protein Guanylate_cyc PF00211.20 CBZ25371.1 - 2.5e-37 128.3 0.0 4.9e-37 127.3 0.0 1.4 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain Uso1_p115_C PF04871.13 CBZ25373.1 - 0.96 9.8 24.8 0.27 11.6 1.1 3.0 2 1 1 3 3 3 0 Uso1 / p115 like vesicle tethering protein, C terminal region FliD_N PF02465.18 CBZ25373.1 - 2.2 9.0 8.1 68 4.3 8.1 3.0 1 1 0 1 1 1 0 Flagellar hook-associated protein 2 N-terminus YabA PF06156.13 CBZ25373.1 - 2.8 8.6 14.9 2.8 8.6 0.1 3.3 3 1 1 4 4 4 0 Initiation control protein YabA SlyX PF04102.12 CBZ25373.1 - 4.9 7.8 31.4 3.1 8.5 3.8 5.1 3 3 1 4 4 4 0 SlyX TPR_2 PF07719.17 CBZ25374.1 - 8.1e-17 59.9 0.4 0.00026 20.9 0.0 4.5 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_1 PF00515.28 CBZ25374.1 - 8.7e-09 34.8 2.9 0.012 15.4 0.0 4.4 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.6 CBZ25374.1 - 3.4e-08 33.7 0.8 0.083 13.2 0.2 3.8 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.6 CBZ25374.1 - 4.1e-08 32.8 2.1 0.054 13.7 0.1 4.5 5 0 0 5 5 4 3 Tetratricopeptide repeat TPR_6 PF13174.6 CBZ25374.1 - 1.3e-05 25.5 0.1 0.071 13.8 0.0 4.8 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_14 PF13428.6 CBZ25374.1 - 1.7e-05 25.3 1.0 3.6 8.6 0.0 4.2 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_19 PF14559.6 CBZ25374.1 - 2.1e-05 25.0 0.2 0.00034 21.1 0.0 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.6 CBZ25374.1 - 0.0001 22.1 4.1 0.25 11.5 0.1 4.3 4 1 0 4 4 4 1 Tetratricopeptide repeat TPR_10 PF13374.6 CBZ25374.1 - 0.00019 21.2 2.8 5 7.1 0.3 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.6 CBZ25374.1 - 0.00041 20.5 0.2 4.8 7.8 0.0 4.4 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_21 PF09976.9 CBZ25374.1 - 0.0057 16.4 0.7 0.39 10.4 0.0 2.9 2 1 1 3 3 3 1 Tetratricopeptide repeat-like domain TPR_16 PF13432.6 CBZ25374.1 - 0.0061 17.2 1.9 7.3 7.3 0.0 3.8 4 0 0 4 4 3 1 Tetratricopeptide repeat ANAPC3 PF12895.7 CBZ25374.1 - 0.0067 16.6 1.9 0.5 10.6 0.0 2.9 3 0 0 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 PknG_TPR PF16918.5 CBZ25374.1 - 0.021 13.6 0.0 0.033 12.9 0.0 1.4 1 0 0 1 1 1 0 Protein kinase G tetratricopeptide repeat TPR_11 PF13414.6 CBZ25374.1 - 0.065 12.9 4.1 6 6.6 0.0 4.2 3 1 0 3 3 3 0 TPR repeat Peptidase_M20 PF01546.28 CBZ25376.1 - 8.3e-11 42.0 0.1 1.2e-10 41.5 0.1 1.1 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 CBZ25376.1 - 1.6e-08 34.4 0.0 3.6e-08 33.3 0.0 1.6 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M42 PF05343.14 CBZ25376.1 - 3e-05 23.2 0.1 0.0002 20.5 0.2 2.0 2 0 0 2 2 2 1 M42 glutamyl aminopeptidase Peptidase_M28 PF04389.17 CBZ25376.1 - 0.00015 21.5 0.1 0.00041 20.1 0.1 1.7 2 0 0 2 2 2 1 Peptidase family M28 FAP206 PF12018.8 CBZ25377.1 - 1.2e-08 34.9 0.0 4.9e-08 32.8 0.0 1.9 2 1 0 2 2 2 1 Domain of unknown function Kinesin PF00225.23 CBZ25378.1 - 5.2e-39 134.1 0.0 5.6e-23 81.4 0.0 2.2 2 0 0 2 2 2 2 Kinesin motor domain Microtub_bd PF16796.5 CBZ25378.1 - 6.8e-08 32.6 0.0 3.9e-07 30.1 0.0 2.0 1 1 1 2 2 2 1 Microtubule binding AAA_22 PF13401.6 CBZ25378.1 - 0.26 11.5 1.2 0.9 9.8 1.2 1.9 1 0 0 1 1 1 0 AAA domain WD40 PF00400.32 CBZ25379.1 - 2.6e-26 91.3 9.8 1.9e-06 28.5 0.0 5.7 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBZ25379.1 - 3.6e-10 40.0 0.0 0.066 13.5 0.0 4.5 1 1 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 CBZ25379.1 - 3.5e-07 29.5 0.1 0.0044 16.0 0.1 3.6 2 1 2 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 CBZ25379.1 - 2.9e-06 27.0 0.0 0.04 13.9 0.0 2.9 2 0 0 2 2 2 2 WD40-like Beta Propeller Repeat Nup160 PF11715.8 CBZ25379.1 - 5.4e-05 22.0 0.8 0.28 9.8 0.0 3.5 2 1 2 4 4 4 2 Nucleoporin Nup120/160 Frtz PF11768.8 CBZ25379.1 - 0.00043 18.7 0.0 0.0039 15.6 0.0 1.9 1 1 1 2 2 2 1 WD repeat-containing and planar cell polarity effector protein Fritz nos_propeller PF18764.1 CBZ25379.1 - 0.058 13.3 0.1 1.1 9.3 0.0 3.0 3 0 0 3 3 3 0 Nitrous oxide reductase propeller repeat Cytochrom_D1 PF02239.16 CBZ25379.1 - 0.15 10.5 0.0 0.44 9.0 0.0 1.7 2 0 0 2 2 2 0 Cytochrome D1 heme domain AZUL PF16558.5 CBZ25379.1 - 0.54 10.5 8.0 2.3 8.5 1.5 4.3 4 0 0 4 4 4 0 Amino-terminal Zinc-binding domain of ubiquitin ligase E3A RCC1 PF00415.18 CBZ25380.1 - 1.3e-55 185.8 27.8 1.8e-13 50.9 0.7 8.4 7 1 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 CBZ25380.1 - 4e-29 99.8 41.9 9.8e-12 44.4 3.1 8.3 9 0 0 9 9 9 6 Regulator of chromosome condensation (RCC1) repeat BTB_2 PF02214.22 CBZ25380.1 - 2.1e-05 24.8 0.0 0.19 12.1 0.0 2.3 2 0 0 2 2 2 2 BTB/POZ domain PALP PF00291.25 CBZ25381.1 - 3.7e-68 230.1 0.1 4.4e-68 229.8 0.1 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme 2Fe-2S_thioredx PF01257.19 CBZ25383.1 - 7.9e-48 162.0 0.0 1.2e-47 161.4 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin-like [2Fe-2S] ferredoxin Histone_H2A_C PF16211.5 CBZ25384.1 - 4.9e-12 45.4 1.1 1.1e-11 44.2 1.1 1.7 1 0 0 1 1 1 1 C-terminus of histone H2A Histone PF00125.24 CBZ25384.1 - 1.2e-09 38.6 0.0 2.2e-09 37.8 0.0 1.5 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 zf-C3HC4_3 PF13920.6 CBZ25385.1 - 1.5e-07 31.1 17.5 1.5e-07 31.1 17.5 3.4 5 0 0 5 5 5 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CBZ25385.1 - 5.1e-06 26.4 9.5 5.1e-06 26.4 9.5 2.4 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 CBZ25385.1 - 1e-05 25.2 15.0 1e-05 25.2 15.0 2.7 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CBZ25385.1 - 3.3e-05 23.7 14.4 3.3e-05 23.7 14.4 2.9 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CBZ25385.1 - 0.00012 22.0 14.0 0.00012 22.0 14.0 2.9 3 0 0 3 3 3 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 CBZ25385.1 - 0.00031 20.8 14.4 0.00031 20.8 14.4 2.6 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 CBZ25385.1 - 0.00052 19.8 14.2 0.00052 19.8 14.2 2.3 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 CBZ25385.1 - 0.00088 19.6 18.6 0.00088 19.6 18.6 3.6 4 0 0 4 4 4 1 Ring finger domain LSM PF01423.22 CBZ25386.1 - 1.8e-07 30.7 0.1 1.9e-06 27.5 0.1 2.1 1 1 0 1 1 1 1 LSM domain DUF667 PF05018.13 CBZ25387.1 - 0.072 12.8 0.0 0.15 11.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF667) dsrm PF00035.26 CBZ25389.1 - 0.052 14.3 0.0 20 6.0 0.0 2.9 2 0 0 2 2 2 0 Double-stranded RNA binding motif Cadherin_2 PF08266.12 CBZ25390.1 - 0.087 12.7 0.0 0.18 11.7 0.0 1.5 1 0 0 1 1 1 0 Cadherin-like Dus PF01207.17 CBZ25391.1 - 4.8e-51 173.7 0.0 1.7e-50 171.9 0.0 1.8 2 0 0 2 2 2 1 Dihydrouridine synthase (Dus) Uso1_p115_C PF04871.13 CBZ25391.1 - 0.019 15.3 4.9 0.037 14.4 4.9 1.3 1 0 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region Mitofilin PF09731.9 CBZ25391.1 - 0.095 11.5 8.9 0.14 11.0 8.9 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Presenilin PF01080.17 CBZ25391.1 - 0.55 8.9 4.1 0.85 8.3 4.1 1.2 1 0 0 1 1 1 0 Presenilin TFIIA PF03153.13 CBZ25391.1 - 0.81 9.6 15.3 1.2 9.1 15.3 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Plasmodium_Vir PF05795.11 CBZ25391.1 - 1.4 8.2 2.3 2.1 7.6 2.3 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Mucin PF01456.17 CBZ25391.1 - 1.9 8.4 16.1 4.1 7.4 11.1 2.4 2 0 0 2 2 2 0 Mucin-like glycoprotein Hid1 PF12722.7 CBZ25391.1 - 2 6.5 5.7 2.7 6.0 5.7 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein dCMP_cyt_deam_1 PF00383.23 CBZ25392.1 - 1.3e-11 44.3 3.8 2.1e-11 43.6 3.8 1.3 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region dCMP_cyt_deam_2 PF08211.12 CBZ25392.1 - 4e-09 36.8 1.7 8.8e-07 29.2 1.3 2.1 2 0 0 2 2 2 2 Cytidine and deoxycytidylate deaminase zinc-binding region LmjF365940-deam PF14421.6 CBZ25392.1 - 0.0026 17.4 5.4 0.0049 16.5 5.4 1.6 1 1 0 1 1 1 1 A distinct subfamily of CDD/CDA-like deaminases Sec20 PF03908.13 CBZ25394.1 - 2.4e-06 27.4 0.4 2.4e-06 27.4 0.4 2.0 3 0 0 3 3 2 1 Sec20 SNARE PF05739.19 CBZ25394.1 - 0.0024 17.8 1.4 0.0061 16.5 1.4 1.7 1 0 0 1 1 1 1 SNARE domain V-SNARE_C PF12352.8 CBZ25394.1 - 0.004 17.4 1.9 0.004 17.4 1.9 1.8 2 0 0 2 2 1 1 Snare region anchored in the vesicle membrane C-terminus Synaptobrevin PF00957.21 CBZ25394.1 - 0.045 13.5 3.7 0.19 11.5 3.6 2.1 1 1 0 1 1 1 0 Synaptobrevin Prominin PF05478.11 CBZ25394.1 - 0.067 11.2 2.7 0.038 11.9 0.7 1.5 2 0 0 2 2 2 0 Prominin Mce4_CUP1 PF11887.8 CBZ25394.1 - 0.07 12.6 0.5 0.37 10.2 0.1 2.0 2 0 0 2 2 2 0 Cholesterol uptake porter CUP1 of Mce4, putative CCDC85 PF10226.9 CBZ25394.1 - 0.075 12.7 0.2 0.075 12.7 0.2 2.6 3 1 0 3 3 3 0 CCDC85 family Baculo_11_kDa PF06143.11 CBZ25394.1 - 0.099 12.2 0.1 0.18 11.4 0.1 1.6 1 0 0 1 1 1 0 Baculovirus 11 kDa family NICE-1 PF15845.5 CBZ25394.1 - 0.11 13.2 5.8 1.3 9.9 0.2 2.8 3 0 0 3 3 3 0 Cysteine-rich C-terminal 1 family V-SNARE PF05008.15 CBZ25394.1 - 0.12 12.8 5.2 0.2 12.0 0.1 2.7 2 1 0 2 2 2 0 Vesicle transport v-SNARE protein N-terminus DUF16 PF01519.16 CBZ25394.1 - 0.29 11.7 1.5 0.59 10.6 0.4 2.0 2 0 0 2 2 2 0 Protein of unknown function DUF16 MCU PF04678.13 CBZ25394.1 - 0.32 11.1 5.6 0.59 10.2 1.2 2.1 2 0 0 2 2 2 0 Mitochondrial calcium uniporter CemA PF03040.14 CBZ25394.1 - 0.41 10.5 1.4 0.74 9.7 0.2 1.9 2 0 0 2 2 2 0 CemA family Spc7 PF08317.11 CBZ25394.1 - 0.83 8.5 7.4 0.3 9.9 1.8 2.1 2 0 0 2 2 2 0 Spc7 kinetochore protein TBCA PF02970.16 CBZ25394.1 - 2.5 8.5 6.8 6.5 7.2 1.6 3.2 3 2 0 3 3 3 0 Tubulin binding cofactor A ERM PF00769.19 CBZ25394.1 - 2.8 7.7 15.4 0.028 14.2 3.8 2.3 2 1 0 2 2 2 0 Ezrin/radixin/moesin family CENP-H PF05837.12 CBZ25394.1 - 6.2 7.3 12.0 1.6 9.1 4.5 2.4 2 0 0 2 2 2 0 Centromere protein H (CENP-H) DUF4618 PF15397.6 CBZ25394.1 - 6.8 6.0 8.1 1.1 8.7 2.1 2.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4618) HR1 PF02185.16 CBZ25394.1 - 7.4 6.8 11.0 0.31 11.2 1.6 3.3 2 2 1 3 3 3 0 Hr1 repeat Pkinase PF00069.25 CBZ25395.1 - 2.1e-61 207.6 0.0 6e-61 206.1 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ25395.1 - 3.9e-40 137.8 0.0 1.3e-38 132.8 0.0 2.2 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CBZ25395.1 - 5.2e-06 25.5 0.0 8.9e-06 24.7 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 CBZ25395.1 - 5.5e-06 25.9 0.0 1.3e-05 24.7 0.0 1.6 1 1 1 2 2 2 1 Kinase-like APH PF01636.23 CBZ25395.1 - 0.0063 16.5 0.0 0.015 15.2 0.0 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 CBZ25395.1 - 0.018 14.4 0.0 0.032 13.6 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family ANTH PF07651.16 CBZ25395.1 - 0.044 12.8 0.1 0.11 11.5 0.0 1.6 2 0 0 2 2 2 0 ANTH domain zf-RING_2 PF13639.6 CBZ25396.1 - 2.1e-07 31.1 7.0 7.4e-07 29.4 7.0 2.0 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 CBZ25396.1 - 3.9e-05 23.6 6.1 3.9e-05 23.6 6.1 2.5 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_5 PF14634.6 CBZ25396.1 - 0.00057 19.8 5.9 0.0021 18.0 5.9 2.1 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.7 CBZ25396.1 - 0.0018 18.5 4.1 0.0078 16.5 4.1 2.2 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 CBZ25396.1 - 0.0035 17.2 6.7 0.0035 17.2 6.7 2.7 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 CBZ25396.1 - 0.012 15.5 10.9 0.21 11.4 10.9 2.9 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 CBZ25396.1 - 0.014 15.1 8.0 0.036 13.8 8.0 1.7 1 0 0 1 1 1 0 RING-like zinc finger zf-Nse PF11789.8 CBZ25396.1 - 0.11 12.3 3.3 0.28 11.0 3.3 1.6 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-ANAPC11 PF12861.7 CBZ25396.1 - 0.3 11.1 2.1 1.1 9.3 2.1 2.0 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_4 PF15227.6 CBZ25396.1 - 0.77 10.0 13.3 0.26 11.5 7.8 3.0 2 1 0 2 2 2 0 zinc finger of C3HC4-type, RING N6-adenineMlase PF10237.9 CBZ25398.1 - 4.6e-33 114.3 1.0 7.2e-33 113.7 1.0 1.3 1 0 0 1 1 1 1 Probable N6-adenine methyltransferase SoxD PF04267.12 CBZ25398.1 - 0.026 14.6 0.3 0.52 10.5 0.1 2.5 2 0 0 2 2 2 0 Sarcosine oxidase, delta subunit family Methyltransf_23 PF13489.6 CBZ25398.1 - 0.089 12.6 0.0 0.17 11.7 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Ammonium_transp PF00909.21 CBZ25399.1 - 8.2 5.0 5.3 13 4.3 5.3 1.2 1 0 0 1 1 1 0 Ammonium Transporter Family Leu_zip PF15294.6 CBZ25400.1 - 0.00099 18.7 5.0 0.0021 17.6 5.0 1.4 1 0 0 1 1 1 1 Leucine zipper BLOC1_2 PF10046.9 CBZ25400.1 - 0.12 12.7 1.0 0.45 10.9 1.0 2.0 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Cnn_1N PF07989.11 CBZ25400.1 - 2.3 8.5 6.8 2.9 8.1 2.2 2.7 2 0 0 2 2 2 0 Centrosomin N-terminal motif 1 Atg14 PF10186.9 CBZ25400.1 - 4.2 6.4 11.4 6.2 5.8 9.9 1.9 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 CENP-H PF05837.12 CBZ25400.1 - 6.6 7.2 14.7 14 6.1 0.0 3.1 3 0 0 3 3 3 0 Centromere protein H (CENP-H) DnaJ PF00226.31 CBZ25402.1 - 5.2e-10 39.3 0.0 9e-10 38.5 0.0 1.4 1 0 0 1 1 1 1 DnaJ domain PhzC-PhzF PF02567.16 CBZ25404.1 - 3.8e-37 128.3 3.3 1e-13 51.4 0.0 4.6 4 1 0 4 4 4 4 Phenazine biosynthesis-like protein Sigma70_r4 PF04545.16 CBZ25404.1 - 0.0083 15.6 0.0 0.021 14.4 0.0 1.7 1 0 0 1 1 1 1 Sigma-70, region 4 Pkinase PF00069.25 CBZ25405.1 - 3.5e-59 200.3 0.0 4.8e-59 199.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ25405.1 - 2.3e-38 131.9 0.0 1.2e-27 96.9 0.1 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase BUD22 PF09073.10 CBZ25405.1 - 4.6e-05 22.9 26.3 8.1e-05 22.1 26.3 1.3 1 0 0 1 1 1 1 BUD22 Pkinase_fungal PF17667.1 CBZ25405.1 - 0.004 16.0 0.0 0.0081 15.0 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase TFIIF_alpha PF05793.12 CBZ25405.1 - 0.008 14.8 16.5 0.013 14.1 16.5 1.3 1 0 0 1 1 1 1 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Haspin_kinase PF12330.8 CBZ25405.1 - 0.023 13.7 0.0 0.037 13.0 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain ABC1 PF03109.16 CBZ25405.1 - 0.048 13.8 0.0 0.11 12.6 0.0 1.6 1 0 0 1 1 1 0 ABC1 family Kinase-like PF14531.6 CBZ25405.1 - 0.078 12.3 0.0 0.19 11.0 0.0 1.6 1 0 0 1 1 1 0 Kinase-like Nop14 PF04147.12 CBZ25405.1 - 0.61 8.2 24.7 0.82 7.8 24.7 1.1 1 0 0 1 1 1 0 Nop14-like family Mpp10 PF04006.12 CBZ25405.1 - 3.2 6.1 17.7 4.7 5.5 17.7 1.1 1 0 0 1 1 1 0 Mpp10 protein CDC45 PF02724.14 CBZ25405.1 - 3.3 5.9 18.6 5.2 5.2 18.6 1.2 1 0 0 1 1 1 0 CDC45-like protein SDA1 PF05285.12 CBZ25405.1 - 8.5 5.7 26.8 13 5.1 26.8 1.2 1 0 0 1 1 1 0 SDA1 Herpes_LMP1 PF05297.11 CBZ25405.1 - 9.5 5.3 12.2 20 4.2 12.2 1.5 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) Sirohm_synth_C PF14823.6 CBZ25409.1 - 0.042 13.5 0.0 0.18 11.5 0.0 2.1 1 0 0 1 1 1 0 Sirohaem biosynthesis protein C-terminal DUF3439 PF11921.8 CBZ25409.1 - 0.49 10.4 13.8 0.13 12.2 1.2 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF3439) zf-ZPR1 PF03367.13 CBZ25409.1 - 0.91 9.4 9.8 0.29 11.0 1.1 2.8 1 1 2 3 3 3 0 ZPR1 zinc-finger domain AAA PF00004.29 CBZ25410.1 - 2.7e-09 37.5 0.0 1e-06 29.2 0.1 2.6 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 CBZ25410.1 - 2.7e-05 24.2 0.1 0.0013 18.6 0.0 2.6 3 0 0 3 3 3 1 Rad17 P-loop domain AAA_30 PF13604.6 CBZ25410.1 - 3.4e-05 23.7 0.7 0.00018 21.3 0.7 2.2 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 CBZ25410.1 - 5.1e-05 23.6 0.3 0.0004 20.7 0.1 2.5 2 1 0 2 2 1 1 AAA domain AAA_16 PF13191.6 CBZ25410.1 - 0.00012 22.5 0.0 0.00012 22.5 0.0 2.6 3 0 0 3 3 2 1 AAA ATPase domain AAA_5 PF07728.14 CBZ25410.1 - 0.00016 21.7 0.0 0.004 17.1 0.0 3.0 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 CBZ25410.1 - 0.0003 21.3 0.0 0.0011 19.5 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.6 CBZ25410.1 - 0.00061 20.1 0.1 0.00061 20.1 0.1 2.7 3 0 0 3 3 3 1 AAA domain AAA_33 PF13671.6 CBZ25410.1 - 0.00078 19.6 2.0 0.0021 18.2 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_assoc_2 PF16193.5 CBZ25410.1 - 0.00086 19.6 0.1 0.0037 17.6 0.0 2.1 1 1 0 1 1 1 1 AAA C-terminal domain RuvB_N PF05496.12 CBZ25410.1 - 0.0017 18.2 0.1 0.0032 17.2 0.1 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain NTPase_1 PF03266.15 CBZ25410.1 - 0.003 17.5 0.0 0.0063 16.4 0.0 1.5 1 0 0 1 1 1 1 NTPase RsgA_GTPase PF03193.16 CBZ25410.1 - 0.0047 16.9 0.0 0.0093 15.9 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase AAA_19 PF13245.6 CBZ25410.1 - 0.0055 17.1 0.0 0.014 15.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.6 CBZ25410.1 - 0.0082 15.7 0.0 0.024 14.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.6 CBZ25410.1 - 0.024 15.0 0.4 0.079 13.4 0.0 2.1 2 0 0 2 2 1 0 AAA domain AAA_14 PF13173.6 CBZ25410.1 - 0.076 13.0 0.0 0.17 11.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 CBZ25410.1 - 0.08 12.4 0.0 0.19 11.2 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region TsaE PF02367.17 CBZ25410.1 - 0.09 12.8 0.0 0.18 11.8 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE dNK PF01712.19 CBZ25410.1 - 0.12 12.2 0.0 0.22 11.4 0.0 1.3 1 0 0 1 1 1 0 Deoxynucleoside kinase ABC_tran PF00005.27 CBZ25410.1 - 0.14 12.6 0.0 0.51 10.9 0.0 1.9 1 0 0 1 1 1 0 ABC transporter NACHT PF05729.12 CBZ25410.1 - 0.17 11.8 0.0 0.5 10.3 0.0 1.8 1 0 0 1 1 1 0 NACHT domain cobW PF02492.19 CBZ25410.1 - 0.21 11.2 0.0 0.42 10.2 0.0 1.5 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_11 PF13086.6 CBZ25410.1 - 8.7 6.0 7.1 1.8 8.3 0.0 2.9 4 0 0 4 4 3 0 AAA domain RRM_1 PF00076.22 CBZ25411.1 - 4.7e-13 48.7 1.1 1.4e-09 37.6 0.0 2.7 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 CBZ25411.1 - 0.0019 17.8 0.0 0.0035 16.9 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) AsnC_trans_reg PF01037.21 CBZ25411.1 - 0.099 12.6 0.0 4.4 7.4 0.0 2.4 2 0 0 2 2 2 0 Lrp/AsnC ligand binding domain SET_assoc PF11767.8 CBZ25411.1 - 0.15 11.7 0.1 3.7 7.3 0.0 2.3 2 0 0 2 2 2 0 Histone lysine methyltransferase SET associated RRM_7 PF16367.5 CBZ25411.1 - 0.16 12.1 0.1 69 3.7 0.0 3.1 2 1 1 3 3 3 0 RNA recognition motif ELF PF03317.13 CBZ25412.1 - 0.021 14.8 0.1 0.039 14.0 0.1 1.4 1 0 0 1 1 1 0 ELF protein Fib_alpha PF08702.10 CBZ25413.1 - 0.12 12.6 4.3 10 6.3 1.0 3.2 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family SKA2 PF16740.5 CBZ25413.1 - 1.2 8.9 15.8 6.2 6.6 6.9 3.4 3 1 0 3 3 3 0 Spindle and kinetochore-associated protein 2 Metallophos PF00149.28 CBZ25414.1 - 1.7e-05 25.4 0.0 3e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase DUF2201_N PF13203.6 CBZ25414.1 - 0.16 11.5 2.0 0.28 10.7 0.1 1.9 2 0 0 2 2 2 0 Putative metallopeptidase domain FadA PF09403.10 CBZ25415.1 - 9.8 6.7 6.2 11 6.6 3.5 2.3 2 0 0 2 2 2 0 Adhesion protein FadA Cation_ATPase_C PF00689.21 CBZ25416.1 - 5.2e-40 137.1 5.6 5.2e-40 137.1 5.6 1.8 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 CBZ25416.1 - 2.2e-32 112.0 0.8 5.3e-32 110.8 0.8 1.7 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase PF13246.6 CBZ25416.1 - 5.7e-26 90.4 0.0 1.3e-25 89.3 0.0 1.6 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 CBZ25416.1 - 3.3e-15 57.0 3.5 1.3e-13 51.7 3.5 3.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 CBZ25416.1 - 7.8e-14 51.1 0.0 1.9e-13 49.9 0.0 1.7 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 CBZ25416.1 - 0.00017 21.4 0.6 0.00031 20.6 0.6 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase ACBP PF00887.19 CBZ25417.1 - 2.3e-29 101.4 0.1 3.5e-16 59.2 0.0 2.7 2 0 0 2 2 2 2 Acyl CoA binding protein ACBP PF00887.19 CBZ25418.1 - 1.6e-26 92.3 0.4 1.9e-26 92.1 0.4 1.1 1 0 0 1 1 1 1 Acyl CoA binding protein Ldl_recept_b PF00058.17 CBZ25419.1 - 0.054 14.0 0.0 16 6.1 0.1 3.0 3 0 0 3 3 3 0 Low-density lipoprotein receptor repeat class B ACBP PF00887.19 CBZ25420.1 - 3.9e-27 94.3 0.7 4.3e-27 94.1 0.7 1.0 1 0 0 1 1 1 1 Acyl CoA binding protein Abhydrolase_6 PF12697.7 CBZ25422.1 - 3e-05 24.7 0.8 4.1e-05 24.3 0.8 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 CBZ25422.1 - 0.001 18.8 0.0 0.0016 18.2 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Cas_GSU0053 PF09617.10 CBZ25422.1 - 0.006 16.6 0.2 0.022 14.7 0.2 1.8 1 1 0 1 1 1 1 CRISPR-associated protein GSU0053 (Cas_GSU0053) PGAP1 PF07819.13 CBZ25422.1 - 0.023 14.4 0.0 0.04 13.6 0.0 1.4 1 0 0 1 1 1 0 PGAP1-like protein PUB_1 PF18486.1 CBZ25422.1 - 0.44 10.4 1.9 0.73 9.7 0.1 2.3 3 0 0 3 3 3 0 PNGase/UBA- or UBX-containing domain EF-hand_13 PF17958.1 CBZ25423.1 - 1.3e-22 79.4 0.1 1.1e-21 76.4 0.0 2.3 2 0 0 2 2 2 1 EF-hand domain EF-hand_7 PF13499.6 CBZ25423.1 - 2.1e-19 69.8 0.4 3.9e-15 56.1 0.0 2.6 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 CBZ25423.1 - 1.8e-06 27.4 0.3 0.00035 20.3 0.0 3.2 4 0 0 4 4 4 1 EF-hand domain EF-hand_5 PF13202.6 CBZ25423.1 - 9.9e-05 21.7 0.1 0.00058 19.2 0.0 2.2 2 0 0 2 2 2 1 EF hand EF-hand_1 PF00036.32 CBZ25423.1 - 0.00038 19.8 0.1 0.0045 16.4 0.0 2.8 3 0 0 3 3 3 1 EF hand EF-hand_8 PF13833.6 CBZ25423.1 - 0.016 15.1 0.4 0.34 10.8 0.0 2.7 3 0 0 3 3 3 0 EF-hand domain pair SPARC_Ca_bdg PF10591.9 CBZ25423.1 - 0.22 11.8 0.3 7.8 6.9 0.0 2.7 3 0 0 3 3 3 0 Secreted protein acidic and rich in cysteine Ca binding region VASt PF16016.5 CBZ25424.1 - 1.3e-15 58.1 0.0 2.1e-15 57.5 0.0 1.2 1 0 0 1 1 1 1 VAD1 Analog of StAR-related lipid transfer domain VASt PF16016.5 CBZ25425.1 - 3.5e-15 56.7 0.0 7e-15 55.7 0.0 1.4 1 0 0 1 1 1 1 VAD1 Analog of StAR-related lipid transfer domain GRAM PF02893.20 CBZ25425.1 - 4.9e-13 48.9 4.5 2.9e-08 33.6 0.4 2.4 2 0 0 2 2 2 2 GRAM domain Pkinase PF00069.25 CBZ25427.1 - 2.7e-67 226.9 0.0 3.4e-67 226.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ25427.1 - 1.3e-38 132.8 0.0 1.7e-38 132.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase POLO_box PF00659.18 CBZ25427.1 - 2.3e-32 111.0 0.0 1.4e-17 63.7 0.0 2.6 2 0 0 2 2 2 2 POLO box duplicated region Kinase-like PF14531.6 CBZ25427.1 - 2e-08 33.9 0.0 2.4e-07 30.3 0.0 2.1 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 CBZ25427.1 - 0.00017 20.5 0.0 0.00032 19.6 0.0 1.5 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 CBZ25427.1 - 0.0014 17.6 0.1 0.0022 17.0 0.1 1.2 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 CBZ25427.1 - 0.012 15.6 5.6 0.035 14.0 0.0 3.5 3 2 2 5 5 5 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 CBZ25427.1 - 0.11 11.5 0.1 0.17 10.9 0.1 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 DUF4404 PF14357.6 CBZ25427.1 - 0.16 12.6 2.5 0.5 11.0 0.7 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4404) TFIIA PF03153.13 CBZ25427.1 - 2.1 8.2 4.6 2.9 7.8 4.6 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit VID27 PF08553.10 CBZ25428.1 - 1.2e-30 106.7 0.0 2e-30 106.1 0.0 1.2 1 0 0 1 1 1 1 VID27 C-terminal WD40-like domain DUF917 PF06032.12 CBZ25429.1 - 0.007 15.2 0.0 0.013 14.3 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF917) DUF664 PF04978.12 CBZ25429.1 - 1.5 9.2 5.0 7.9 6.9 0.2 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF664) Pkinase PF00069.25 CBZ25431.1 - 6.4e-22 78.2 0.0 1.7e-10 40.7 0.0 4.1 4 0 0 4 4 4 4 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ25431.1 - 0.00018 20.9 0.0 0.088 12.1 0.0 2.9 3 0 0 3 3 3 2 Protein tyrosine kinase NT5C PF06941.12 CBZ25432.1 - 0.0042 17.0 0.0 0.0084 16.0 0.0 1.4 1 0 0 1 1 1 1 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C) Tudor-knot PF11717.8 CBZ25432.1 - 0.046 13.6 0.1 0.099 12.5 0.1 1.5 1 0 0 1 1 1 0 RNA binding activity-knot of a chromodomain DUF1117 PF06547.12 CBZ25433.1 - 3 8.4 5.5 7.7 7.1 0.1 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF1117) FH2 PF02181.23 CBZ25433.1 - 7.9 5.5 8.5 2.7 7.0 4.3 2.2 2 1 0 2 2 2 0 Formin Homology 2 Domain PRKG1_interact PF15898.5 CBZ25433.1 - 9.4 7.2 9.1 1.1 10.2 2.3 2.8 2 1 1 3 3 3 0 cGMP-dependent protein kinase interacting domain Methyltransf_16 PF10294.9 CBZ25434.1 - 1e-17 64.4 0.0 4.8e-13 49.2 0.0 2.7 2 1 0 2 2 2 2 Lysine methyltransferase Myb_DNA-binding PF00249.31 CBZ25435.1 - 1.5e-19 69.9 4.5 3.2e-11 43.2 0.3 2.6 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 CBZ25435.1 - 1.7e-14 53.8 10.6 1.4e-08 34.8 0.3 2.9 2 0 0 2 2 2 2 Myb-like DNA-binding domain RNA_pol_Rpb2_7 PF04560.20 CBZ25435.1 - 0.019 15.3 0.0 2.4 8.6 0.0 2.5 2 0 0 2 2 2 0 RNA polymerase Rpb2, domain 7 Myb_DNA-bind_4 PF13837.6 CBZ25435.1 - 1.3 9.5 8.5 1.5 9.3 0.1 3.5 4 0 0 4 4 4 0 Myb/SANT-like DNA-binding domain DUF2953 PF11167.8 CBZ25436.1 - 0.022 14.8 0.0 0.049 13.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2953) IMPDH PF00478.25 CBZ25437.1 - 4.4e-146 486.3 0.1 7.3e-146 485.6 0.1 1.3 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain CBS PF00571.28 CBZ25437.1 - 4.6e-11 43.0 0.1 0.00019 21.8 0.0 2.7 2 0 0 2 2 2 2 CBS domain NMO PF03060.15 CBZ25437.1 - 2.9e-07 30.2 8.7 0.0022 17.4 9.4 2.4 2 1 0 2 2 2 2 Nitronate monooxygenase FMN_dh PF01070.18 CBZ25437.1 - 6.2e-06 25.5 12.1 1.2e-05 24.6 11.7 1.6 1 1 0 1 1 1 1 FMN-dependent dehydrogenase His_biosynth PF00977.21 CBZ25437.1 - 0.00081 18.9 2.5 0.023 14.2 0.1 2.3 1 1 0 2 2 2 1 Histidine biosynthesis protein Glu_synthase PF01645.17 CBZ25437.1 - 0.0029 16.8 4.7 0.0055 15.9 4.7 1.4 1 0 0 1 1 1 1 Conserved region in glutamate synthase ThiG PF05690.14 CBZ25437.1 - 0.0038 16.6 0.6 0.0038 16.6 0.6 2.5 2 0 0 2 2 2 1 Thiazole biosynthesis protein ThiG DHO_dh PF01180.21 CBZ25437.1 - 0.0053 16.0 5.4 0.024 13.9 0.5 2.3 2 0 0 2 2 2 1 Dihydroorotate dehydrogenase PcrB PF01884.17 CBZ25437.1 - 8.4 5.8 7.5 3 7.2 0.1 3.2 4 0 0 4 4 4 0 PcrB family Lysine_decarbox PF03641.14 CBZ25438.1 - 5.1e-28 97.8 0.1 8e-28 97.2 0.1 1.3 1 0 0 1 1 1 1 Possible lysine decarboxylase LDcluster4 PF18306.1 CBZ25438.1 - 2.5e-11 43.4 0.8 4e-11 42.7 0.8 1.2 1 0 0 1 1 1 1 SLOG cluster4 family ABM PF03992.16 CBZ25438.1 - 1.6e-08 34.5 0.0 3.3e-08 33.5 0.0 1.5 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase LSDAT_prok PF18171.1 CBZ25438.1 - 0.075 12.3 0.1 0.16 11.2 0.1 1.5 2 0 0 2 2 2 0 SLOG in TRPM, prokaryote Kinesin PF00225.23 CBZ25439.1 - 6.6e-104 347.4 0.2 6.6e-104 347.4 0.2 2.2 3 0 0 3 3 3 1 Kinesin motor domain Microtub_bd PF16796.5 CBZ25439.1 - 1.1e-24 87.1 0.6 5e-24 84.9 0.1 2.5 2 0 0 2 2 2 1 Microtubule binding FAM184 PF15665.5 CBZ25439.1 - 7.2 6.3 85.5 0.81 9.4 20.2 3.7 2 1 1 3 3 3 0 Family with sequence similarity 184, A and B G-patch PF01585.23 CBZ25441.1 - 1.2e-13 50.7 0.4 2.9e-13 49.5 0.4 1.7 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 CBZ25441.1 - 0.0019 18.3 0.4 0.005 16.9 0.4 1.7 1 0 0 1 1 1 1 G-patch domain Macoilin PF09726.9 CBZ25441.1 - 0.26 9.8 3.1 0.26 9.8 3.1 1.0 1 0 0 1 1 1 0 Macoilin family DNA_pol_phi PF04931.13 CBZ25441.1 - 0.9 7.6 5.3 1.1 7.3 5.3 1.0 1 0 0 1 1 1 0 DNA polymerase phi Presenilin PF01080.17 CBZ25441.1 - 5.2 5.7 4.3 6.6 5.4 4.3 1.1 1 0 0 1 1 1 0 Presenilin DBR1 PF05011.13 CBZ25443.1 - 7.6e-08 32.9 0.0 3.3e-07 30.8 0.0 2.0 2 0 0 2 2 2 1 Lariat debranching enzyme, C-terminal domain Metallophos PF00149.28 CBZ25443.1 - 6.8e-05 23.5 0.0 0.00018 22.1 0.0 1.7 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase ATP-synt_10 PF05176.14 CBZ25444.1 - 0.0028 16.9 0.0 0.0056 15.9 0.0 1.5 1 0 0 1 1 1 1 ATP10 protein MdcG PF10620.9 CBZ25445.1 - 0.0031 17.3 0.3 0.0045 16.8 0.3 1.2 1 0 0 1 1 1 1 Phosphoribosyl-dephospho-CoA transferase MdcG Arg_tRNA_synt_N PF03485.16 CBZ25445.1 - 0.077 13.6 0.1 0.15 12.7 0.1 1.5 1 0 0 1 1 1 0 Arginyl tRNA synthetase N terminal domain DUF1935 PF09149.10 CBZ25447.1 - 4.8e-34 116.8 0.0 1.1e-33 115.7 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1935) META PF03724.16 CBZ25447.1 - 2.7e-29 101.3 1.2 3.9e-09 36.4 0.1 3.2 2 1 1 3 3 3 3 META domain YabA PF06156.13 CBZ25447.1 - 0.1 13.3 0.1 1.5 9.5 0.0 2.5 2 0 0 2 2 2 0 Initiation control protein YabA Fzo_mitofusin PF04799.13 CBZ25448.1 - 0.13 11.8 0.0 0.26 10.8 0.0 1.4 1 0 0 1 1 1 0 fzo-like conserved region META PF03724.16 CBZ25449.1 - 2.8e-10 40.1 0.0 3.4e-10 39.8 0.0 1.0 1 0 0 1 1 1 1 META domain LRR_6 PF13516.6 CBZ25450.1 - 1.5e-12 46.5 3.7 0.058 13.5 0.1 5.9 6 0 0 6 6 6 4 Leucine Rich repeat LRR_4 PF12799.7 CBZ25450.1 - 6.6e-08 32.7 1.9 0.52 10.8 0.1 4.6 3 1 1 4 4 4 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 CBZ25450.1 - 0.00021 21.4 0.0 1.1e+02 4.0 0.0 6.1 6 0 0 6 6 6 0 Leucine Rich Repeat LRR_8 PF13855.6 CBZ25450.1 - 0.0016 18.2 5.0 9.4 6.1 0.1 4.3 3 2 0 3 3 3 3 Leucine rich repeat Acyltransferase PF01553.21 CBZ25451.1 - 2.9e-13 49.6 0.0 5.2e-13 48.8 0.0 1.4 1 0 0 1 1 1 1 Acyltransferase Acyltransf_C PF16076.5 CBZ25451.1 - 0.00019 21.4 0.0 0.0019 18.2 0.0 2.4 1 1 0 1 1 1 1 Acyltransferase C-terminus Sec63 PF02889.16 CBZ25452.1 - 3.2e-57 193.6 0.0 4.9e-52 176.6 0.0 2.4 2 0 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.29 CBZ25452.1 - 9.7e-32 110.1 0.5 5e-24 85.0 0.5 3.0 2 0 0 2 2 2 2 DEAD/DEAH box helicase ResIII PF04851.15 CBZ25452.1 - 2.1e-11 44.1 0.0 4.3e-10 39.9 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_PWI PF18149.1 CBZ25452.1 - 3.3e-09 36.9 0.0 1.1e-08 35.2 0.0 1.9 1 0 0 1 1 1 1 N-terminal helicase PWI domain Helicase_C PF00271.31 CBZ25452.1 - 3e-08 34.0 0.0 1.2e-06 28.9 0.0 2.8 1 1 0 1 1 1 1 Helicase conserved C-terminal domain AAA_16 PF13191.6 CBZ25452.1 - 0.0018 18.7 4.6 1.1 9.6 0.4 3.9 3 0 0 3 3 3 2 AAA ATPase domain AAA_19 PF13245.6 CBZ25452.1 - 0.14 12.5 3.7 0.76 10.1 0.8 3.3 4 0 0 4 4 4 0 AAA domain AAA_11 PF13086.6 CBZ25452.1 - 2.1 8.1 4.1 7 6.3 0.0 3.2 3 1 0 3 3 3 0 AAA domain FH2 PF02181.23 CBZ25453.1 - 1.4e-48 165.9 0.0 2.1e-48 165.4 0.0 1.2 1 0 0 1 1 1 1 Formin Homology 2 Domain Med9 PF07544.13 CBZ25453.1 - 0.00011 22.2 0.3 0.0004 20.4 0.3 1.9 1 0 0 1 1 1 1 RNA polymerase II transcription mediator complex subunit 9 CUE PF02845.16 CBZ25453.1 - 0.0035 17.0 0.0 0.0072 16.0 0.0 1.5 1 0 0 1 1 1 1 CUE domain CorA PF01544.18 CBZ25453.1 - 0.031 13.6 0.1 0.058 12.7 0.1 1.4 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein RPW8 PF05659.11 CBZ25453.1 - 0.041 13.6 0.5 0.11 12.2 0.4 1.6 1 1 0 1 1 1 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 PCIF1_WW PF12237.8 CBZ25454.1 - 1.9e-33 115.5 0.1 4e-32 111.2 0.2 2.6 2 1 0 2 2 2 1 Phosphorylated CTD interacting factor 1 WW domain PDEase_I PF00233.19 CBZ25455.1 - 5.2e-15 55.8 0.0 1.2e-14 54.6 0.0 1.6 1 1 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase BTB PF00651.31 CBZ25456.1 - 0.03 14.6 0.0 2.7 8.3 0.0 2.5 2 0 0 2 2 2 0 BTB/POZ domain Mak10 PF04112.13 CBZ25457.1 - 5.4e-07 29.3 0.1 2.7e-05 23.7 0.1 2.5 1 1 0 1 1 1 1 Mak10 subunit, NatC N(alpha)-terminal acetyltransferase PI3_PI4_kinase PF00454.27 CBZ25458.1 - 0.0021 17.9 0.0 0.0039 17.0 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase Abhydrolase_1 PF00561.20 CBZ25460.1 - 6.4e-17 62.0 0.5 1e-11 45.0 0.5 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 CBZ25460.1 - 6.5e-08 33.4 2.7 9e-08 33.0 2.7 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 CBZ25460.1 - 8.6e-07 28.5 0.1 5.8e-06 25.8 0.1 2.0 2 1 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_4 PF08386.10 CBZ25460.1 - 0.0023 18.0 0.0 0.0041 17.2 0.0 1.3 1 0 0 1 1 1 1 TAP-like protein FSH1 PF03959.13 CBZ25460.1 - 0.0044 16.7 0.6 0.0056 16.4 0.0 1.4 2 0 0 2 2 2 1 Serine hydrolase (FSH1) Peptidase_S9 PF00326.21 CBZ25460.1 - 0.0086 15.6 0.1 0.063 12.7 0.0 2.1 2 0 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_2 PF02230.16 CBZ25460.1 - 0.074 12.8 0.0 0.74 9.6 0.0 2.0 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Esterase PF00756.20 CBZ25460.1 - 0.1 12.2 0.0 0.12 12.0 0.0 1.2 1 0 0 1 1 1 0 Putative esterase LIP PF03583.14 CBZ25460.1 - 0.2 10.9 0.0 0.63 9.3 0.0 1.7 2 0 0 2 2 2 0 Secretory lipase GlcNAc PF11397.8 CBZ25461.1 - 5.9e-140 466.7 0.0 7.1e-140 466.4 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase (GlcNAc) DUF2452 PF10504.9 CBZ25461.1 - 0.076 12.5 0.0 0.13 11.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2452) Abhydrolase_1 PF00561.20 CBZ25463.1 - 1.7e-16 60.6 0.0 2.9e-15 56.6 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 CBZ25463.1 - 1.3e-09 39.0 2.2 4.4e-09 37.3 2.2 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 CBZ25463.1 - 5.7e-08 32.3 0.1 0.0041 16.4 0.1 2.5 2 1 0 2 2 2 2 Serine aminopeptidase, S33 Esterase_phd PF10503.9 CBZ25463.1 - 9.6e-06 25.2 0.6 0.14 11.6 0.0 2.5 2 0 0 2 2 2 2 Esterase PHB depolymerase Ndr PF03096.14 CBZ25463.1 - 6.4e-05 21.8 0.0 0.00011 21.0 0.0 1.3 1 0 0 1 1 1 1 Ndr family Abhydrolase_4 PF08386.10 CBZ25463.1 - 0.00013 22.1 0.0 0.00027 21.0 0.0 1.5 1 0 0 1 1 1 1 TAP-like protein Abhydrolase_3 PF07859.13 CBZ25463.1 - 0.001 19.0 0.0 0.23 11.3 0.0 2.7 3 0 0 3 3 3 1 alpha/beta hydrolase fold Esterase PF00756.20 CBZ25463.1 - 0.0019 17.9 0.0 0.0027 17.4 0.0 1.3 1 0 0 1 1 1 1 Putative esterase Ser_hydrolase PF06821.13 CBZ25463.1 - 0.0035 17.2 0.0 0.008 16.1 0.0 1.5 1 0 0 1 1 1 1 Serine hydrolase FSH1 PF03959.13 CBZ25463.1 - 0.022 14.4 0.0 0.11 12.2 0.0 1.9 2 0 0 2 2 2 0 Serine hydrolase (FSH1) Peptidase_S9 PF00326.21 CBZ25463.1 - 0.068 12.6 0.0 5.1 6.5 0.0 2.3 2 0 0 2 2 2 0 Prolyl oligopeptidase family Patatin PF01734.22 CBZ25463.1 - 0.072 13.3 1.7 0.13 12.4 1.7 1.5 1 1 0 1 1 1 0 Patatin-like phospholipase PGAP1 PF07819.13 CBZ25463.1 - 0.11 12.2 0.0 0.17 11.6 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein Abhydrolase_1 PF00561.20 CBZ25464.1 - 3.1e-19 69.6 0.0 5.4e-18 65.6 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 CBZ25464.1 - 3.4e-14 52.7 0.0 1.6e-09 37.4 0.0 2.1 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 CBZ25464.1 - 2.1e-11 44.9 1.9 3.4e-11 44.2 1.9 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Esterase_phd PF10503.9 CBZ25464.1 - 0.00019 21.0 0.2 0.044 13.3 0.0 2.2 2 0 0 2 2 2 2 Esterase PHB depolymerase Esterase PF00756.20 CBZ25464.1 - 0.00021 21.0 0.0 0.0004 20.1 0.1 1.5 2 0 0 2 2 2 1 Putative esterase Ndr PF03096.14 CBZ25464.1 - 0.00041 19.1 0.0 0.0024 16.6 0.0 1.9 2 0 0 2 2 2 1 Ndr family Abhydrolase_4 PF08386.10 CBZ25464.1 - 0.0019 18.3 0.0 0.0041 17.2 0.0 1.5 1 0 0 1 1 1 1 TAP-like protein Abhydrolase_2 PF02230.16 CBZ25464.1 - 0.014 15.3 0.0 1.2 8.9 0.0 2.2 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase DLH PF01738.18 CBZ25464.1 - 0.035 13.7 0.0 0.3 10.6 0.0 2.1 2 0 0 2 2 2 0 Dienelactone hydrolase family Acyl_transf_2 PF02273.15 CBZ25464.1 - 0.13 11.4 0.0 0.23 10.7 0.0 1.3 1 0 0 1 1 1 0 Acyl transferase FIST PF08495.10 CBZ25464.1 - 0.14 12.1 0.0 0.24 11.4 0.0 1.4 1 0 0 1 1 1 0 FIST N domain Abhydrolase_1 PF00561.20 CBZ25465.1 - 9.7e-18 64.7 0.0 1.7e-17 64.0 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 CBZ25465.1 - 1.4e-11 44.1 0.0 5e-11 42.3 0.0 1.9 2 1 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 CBZ25465.1 - 1e-07 32.8 3.9 1e-07 32.8 3.9 2.0 2 1 1 3 3 3 1 Alpha/beta hydrolase family Thioesterase PF00975.20 CBZ25465.1 - 0.0014 18.8 0.0 0.0026 17.9 0.0 1.3 1 0 0 1 1 1 1 Thioesterase domain Esterase PF00756.20 CBZ25465.1 - 0.073 12.7 0.0 0.21 11.2 0.0 1.7 2 0 0 2 2 2 0 Putative esterase Abhydrolase_4 PF08386.10 CBZ25465.1 - 0.12 12.6 0.0 0.35 11.0 0.0 1.8 1 0 0 1 1 1 0 TAP-like protein ThiG PF05690.14 CBZ25465.1 - 0.47 9.7 7.1 6.2 6.1 0.0 2.4 2 0 0 2 2 2 0 Thiazole biosynthesis protein ThiG PLAC8 PF04749.17 CBZ25466.1 - 0.072 14.1 12.0 0.24 12.4 12.0 1.8 1 1 0 1 1 1 0 PLAC8 family DUF4570 PF15134.6 CBZ25467.1 - 0.083 12.9 1.1 0.17 11.9 1.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4570) KxDL PF10241.9 CBZ25467.1 - 0.098 12.9 0.8 0.2 11.9 0.6 1.6 1 1 0 1 1 1 0 Uncharacterized conserved protein Spc7 PF08317.11 CBZ25467.1 - 2.9 6.7 6.3 4.2 6.2 6.3 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein ADIP PF11559.8 CBZ25467.1 - 4.8 7.3 6.7 9.2 6.3 6.7 1.4 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding UCH PF00443.29 CBZ25468.1 - 3.9e-18 65.9 0.0 1.4e-17 64.1 0.0 1.8 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 CBZ25468.1 - 4e-07 29.9 0.0 7e-07 29.1 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DUF2385 PF09539.10 CBZ25468.1 - 0.16 12.5 0.1 0.42 11.2 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2385) Steroid_dh PF02544.16 CBZ25469.1 - 2e-24 86.3 1.3 9.2e-10 38.7 0.0 4.3 4 0 0 4 4 4 4 3-oxo-5-alpha-steroid 4-dehydrogenase Kinesin PF00225.23 CBZ25470.1 - 6.3e-86 288.3 0.1 9.3e-86 287.8 0.1 1.3 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 CBZ25470.1 - 5.9e-24 84.7 0.0 1.4e-23 83.5 0.0 1.6 1 0 0 1 1 1 1 Microtubule binding Calpain_III PF01067.22 CBZ25470.1 - 2.2e-14 53.9 0.0 3.4e-11 43.6 0.0 3.1 2 0 0 2 2 2 2 Calpain large subunit, domain III Arm PF00514.23 CBZ25470.1 - 2.5e-08 33.6 1.6 0.37 10.9 0.1 5.2 5 0 0 5 5 5 3 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.6 CBZ25470.1 - 0.0019 18.6 3.4 0.06 13.7 0.3 3.7 2 1 2 4 4 4 2 HEAT repeats Atx10homo_assoc PF09759.9 CBZ25470.1 - 0.5 10.4 3.6 1.3 9.1 0.0 3.4 5 0 0 5 5 5 0 Spinocerebellar ataxia type 10 protein domain Methyltr_RsmB-F PF01189.17 CBZ25472.1 - 3.4e-28 98.7 0.0 2.9e-17 63.0 0.0 4.5 4 1 0 4 4 4 2 16S rRNA methyltransferase RsmB/F WW PF00397.26 CBZ25473.1 - 3.7e-10 39.7 0.2 7.2e-10 38.8 0.2 1.5 1 0 0 1 1 1 1 WW domain DUF746 PF05344.11 CBZ25473.1 - 0.082 12.7 0.3 0.5 10.2 0.1 2.4 2 0 0 2 2 2 0 Domain of Unknown Function (DUF746) XRN_N PF03159.18 CBZ25474.1 - 3.3e-70 236.3 0.0 4.9e-70 235.7 0.0 1.3 1 0 0 1 1 1 1 XRN 5'-3' exonuclease N-terminus XRN_M PF17846.1 CBZ25474.1 - 1e-36 126.9 0.0 5e-21 75.2 0.0 2.1 1 1 1 2 2 2 2 Xrn1 helical domain zf-RanBP PF00641.18 CBZ25474.1 - 3.5e-06 26.2 1.7 7.1e-06 25.2 1.7 1.5 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others zf-C3HC4_3 PF13920.6 CBZ25474.1 - 0.18 11.7 1.1 0.55 10.1 1.1 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) UDPGP PF01704.18 CBZ25475.1 - 9e-10 37.7 0.0 1.4e-09 37.1 0.0 1.2 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase DUF1844 PF08899.11 CBZ25476.1 - 0.14 12.4 0.2 0.33 11.3 0.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1844) Striatin PF08232.12 CBZ25477.1 - 0.0037 17.9 0.9 0.0037 17.9 0.9 1.7 2 0 0 2 2 2 1 Striatin family MAD PF05557.13 CBZ25477.1 - 0.16 10.3 2.3 0.24 9.7 2.3 1.1 1 0 0 1 1 1 0 Mitotic checkpoint protein PRIMA1 PF16101.5 CBZ25477.1 - 1.9 8.5 5.3 7.8 6.6 0.4 2.8 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 ATG16 PF08614.11 CBZ25479.1 - 0.0012 19.1 0.5 0.0012 19.1 0.5 3.7 3 1 1 4 4 3 2 Autophagy protein 16 (ATG16) SlyX PF04102.12 CBZ25479.1 - 0.005 17.4 2.9 1.1 10.0 0.8 2.6 2 0 0 2 2 2 1 SlyX FlaC_arch PF05377.11 CBZ25479.1 - 0.056 13.8 6.3 2 8.9 0.4 2.4 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) UPF0242 PF06785.11 CBZ25479.1 - 0.095 12.8 3.8 0.28 11.3 3.8 1.6 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus CtIP_N PF10482.9 CBZ25479.1 - 0.4 10.7 3.9 0.14 12.2 0.4 2.0 2 0 0 2 2 2 0 Tumour-suppressor protein CtIP N-terminal domain DUF4407 PF14362.6 CBZ25479.1 - 0.4 10.0 4.1 0.93 8.8 4.1 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Cnn_1N PF07989.11 CBZ25479.1 - 0.43 10.8 5.7 11 6.3 0.2 2.6 2 0 0 2 2 2 0 Centrosomin N-terminal motif 1 ADIP PF11559.8 CBZ25479.1 - 0.47 10.5 10.1 0.39 10.8 1.6 2.4 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding BRE1 PF08647.11 CBZ25479.1 - 0.6 10.2 4.9 0.51 10.5 0.2 2.2 2 0 0 2 2 2 0 BRE1 E3 ubiquitin ligase PI3K_P85_iSH2 PF16454.5 CBZ25479.1 - 0.78 9.3 4.6 8.3 6.0 0.5 2.2 2 0 0 2 2 2 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain CLZ PF16526.5 CBZ25479.1 - 0.91 9.9 6.4 8.3 6.9 0.7 2.5 2 0 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels ERM PF00769.19 CBZ25479.1 - 2 8.1 12.7 2 8.2 3.6 2.4 2 0 0 2 2 2 0 Ezrin/radixin/moesin family MAD PF05557.13 CBZ25479.1 - 2.5 6.4 5.2 4.5 5.5 0.9 2.0 2 0 0 2 2 2 0 Mitotic checkpoint protein FAM76 PF16046.5 CBZ25479.1 - 4.1 6.7 5.1 17 4.6 0.7 2.7 1 1 1 2 2 2 0 FAM76 protein DivIC PF04977.15 CBZ25479.1 - 4.6 7.1 7.2 1.4 8.7 0.8 2.6 2 0 0 2 2 2 0 Septum formation initiator DUF4200 PF13863.6 CBZ25479.1 - 4.7 7.6 8.0 5.4 7.4 0.9 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) DUF3584 PF12128.8 CBZ25479.1 - 5.2 4.5 5.8 8.9 3.7 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) PKcGMP_CC PF16808.5 CBZ25479.1 - 6.8 6.6 7.5 0.26 11.2 1.6 1.7 2 0 0 2 2 1 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Motile_Sperm PF00635.26 CBZ25480.1 - 1.6e-10 40.8 0.0 3e-10 39.9 0.0 1.4 1 0 0 1 1 1 1 MSP (Major sperm protein) domain Histone PF00125.24 CBZ25481.1 - 5.1e-10 39.8 1.0 6.8e-10 39.4 1.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 GMP_synt_C PF00958.22 CBZ25481.1 - 0.024 14.7 1.3 0.033 14.2 0.7 1.5 1 1 1 2 2 2 0 GMP synthase C terminal domain CBFD_NFYB_HMF PF00808.23 CBZ25481.1 - 0.041 14.2 0.2 0.084 13.2 0.2 1.6 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone ArsA_ATPase PF02374.15 CBZ25481.1 - 0.064 12.4 0.2 0.069 12.3 0.2 1.0 1 0 0 1 1 1 0 Anion-transporting ATPase DUF3781 PF12636.7 CBZ25481.1 - 0.068 13.1 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3781) DUF4661 PF15576.6 CBZ25482.1 - 0.67 9.8 9.4 0.063 13.2 0.3 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4661) TPR_2 PF07719.17 CBZ25483.1 - 4.2e-08 32.7 3.5 0.082 13.1 0.0 5.5 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_8 PF13181.6 CBZ25483.1 - 8.4e-05 22.5 0.0 0.74 10.2 0.0 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 CBZ25483.1 - 0.0001 22.8 8.7 0.0092 16.6 0.1 5.1 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.6 CBZ25483.1 - 0.00013 22.5 20.7 1 10.4 0.1 7.8 6 2 3 9 9 9 3 Tetratricopeptide repeat TPR_17 PF13431.6 CBZ25483.1 - 0.00026 21.2 0.0 1.3 9.6 0.0 4.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 CBZ25483.1 - 0.00081 19.1 0.0 0.59 10.1 0.0 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.6 CBZ25483.1 - 0.013 15.4 3.3 14 6.0 0.0 5.3 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_12 PF13424.6 CBZ25483.1 - 0.11 12.8 6.3 2.2 8.7 0.0 4.9 4 0 0 4 4 4 0 Tetratricopeptide repeat GNAT_acetyltr_2 PF13718.6 CBZ25484.1 - 5.2e-82 274.6 0.0 3.4e-81 272.0 0.0 2.2 2 0 0 2 2 2 1 GNAT acetyltransferase 2 Helicase_RecD PF05127.14 CBZ25484.1 - 4.7e-59 199.2 0.0 1.5e-58 197.5 0.0 1.9 2 0 0 2 2 2 1 Helicase DUF1726 PF08351.11 CBZ25484.1 - 4.1e-30 103.6 0.1 1.3e-29 101.9 0.1 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1726) tRNA_bind_2 PF13725.6 CBZ25484.1 - 2.8e-23 82.8 0.0 1.5e-22 80.5 0.0 2.0 1 1 0 1 1 1 1 Possible tRNA binding domain AAA_30 PF13604.6 CBZ25484.1 - 8.2e-05 22.4 0.2 0.001 18.9 0.1 2.7 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 CBZ25484.1 - 0.00064 20.1 0.5 0.0059 16.9 0.0 2.4 2 0 0 2 2 2 1 AAA domain Oscp1 PF10188.9 CBZ25485.1 - 1.7e-54 184.6 0.2 2.2e-54 184.2 0.2 1.1 1 0 0 1 1 1 1 Organic solute transport protein 1 Sterol-sensing PF12349.8 CBZ25485.1 - 0.083 12.7 1.0 0.15 11.9 1.0 1.4 1 0 0 1 1 1 0 Sterol-sensing domain of SREBP cleavage-activation eIF2A PF08662.11 CBZ25488.1 - 1.1e-12 48.3 0.0 3.1e-12 46.8 0.0 1.8 2 0 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A PAXNEB PF05625.11 CBZ25488.1 - 0.56 9.3 3.8 0.83 8.7 3.8 1.1 1 0 0 1 1 1 0 PAXNEB protein Methyltransf_32 PF13679.6 CBZ25490.1 - 8.7e-14 51.8 2.1 1e-06 28.9 1.1 2.6 2 0 0 2 2 2 2 Methyltransferase domain ubiquitin PF00240.23 CBZ25492.1 - 0.18 11.5 0.0 0.34 10.7 0.0 1.3 1 0 0 1 1 1 0 Ubiquitin family CTP_transf_like PF01467.26 CBZ25494.1 - 5.9e-19 68.7 0.0 7.7e-19 68.3 0.0 1.1 1 0 0 1 1 1 1 Cytidylyltransferase-like Cyt-b5 PF00173.28 CBZ25495.1 - 3.5e-15 55.9 0.0 5.6e-15 55.2 0.0 1.3 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain ALO PF04030.14 CBZ25496.1 - 1.3e-58 198.8 1.3 1.2e-54 185.8 0.2 2.2 2 0 0 2 2 2 2 D-arabinono-1,4-lactone oxidase FAD_binding_4 PF01565.23 CBZ25496.1 - 1.1e-20 73.8 0.7 1.7e-20 73.2 0.7 1.2 1 0 0 1 1 1 1 FAD binding domain SDA1 PF05285.12 CBZ25497.1 - 4.2e-76 256.6 58.7 1.2e-43 149.9 3.6 2.8 2 1 1 3 3 3 2 SDA1 NUC130_3NT PF08158.12 CBZ25497.1 - 8.5e-13 48.4 0.1 3e-12 46.7 0.1 2.1 1 0 0 1 1 1 1 NUC130/3NT domain IQ PF00612.27 CBZ25499.1 - 8.7e-10 37.5 52.4 0.0079 15.9 1.8 7.9 7 1 0 7 7 7 6 IQ calmodulin-binding motif Inositol_P PF00459.25 CBZ25500.1 - 3e-51 174.6 0.1 3.5e-51 174.3 0.1 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family Peptidase_C65 PF10275.9 CBZ25501.1 - 1.4e-64 217.9 0.1 1.6e-64 217.8 0.1 1.0 1 0 0 1 1 1 1 Peptidase C65 Otubain OTU PF02338.19 CBZ25501.1 - 2.3e-05 24.9 0.0 0.002 18.6 0.0 2.6 2 1 1 3 3 3 1 OTU-like cysteine protease zf-ZPR1 PF03367.13 CBZ25502.1 - 1.3e-110 366.4 0.0 1.2e-56 191.0 0.0 2.3 2 0 0 2 2 2 2 ZPR1 zinc-finger domain HypA PF01155.19 CBZ25502.1 - 0.0061 16.6 2.9 1.2 9.2 0.4 2.6 2 0 0 2 2 2 2 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-RRPl_C4 PF17026.5 CBZ25502.1 - 0.18 12.0 0.1 0.18 12.0 0.1 2.9 2 1 0 3 3 3 0 Putative ribonucleoprotein zinc-finger pf C4 type zinc-ribbons_6 PF07191.12 CBZ25502.1 - 1 9.4 6.9 2 8.5 0.3 2.6 2 0 0 2 2 2 0 zinc-ribbons FAM76 PF16046.5 CBZ25503.1 - 2.1 7.6 16.8 2.9 7.1 14.6 1.8 1 1 1 2 2 2 0 FAM76 protein LMBR1 PF04791.16 CBZ25503.1 - 7.9 5.3 8.2 10 4.9 8.2 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein MFS_1 PF07690.16 CBZ25504.1 - 7.6e-23 81.0 47.7 5.2e-21 75.0 42.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 CBZ25504.1 - 1.8e-05 23.5 16.4 1.8e-05 23.5 16.4 2.9 2 1 1 3 3 3 2 MFS/sugar transport protein Ion_trans PF00520.31 CBZ25505.1 - 2.7e-64 216.8 56.5 7.3e-27 94.2 8.3 4.1 4 0 0 4 4 4 4 Ion transport protein DUF3096 PF11295.8 CBZ25505.1 - 0.59 9.8 9.2 6.1 6.6 0.0 3.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3096) RabGAP-TBC PF00566.18 CBZ25506.1 - 2.8e-16 59.8 0.3 6e-16 58.7 0.3 1.5 1 1 0 1 1 1 1 Rab-GTPase-TBC domain Ferrochelatase PF00762.19 CBZ25507.1 - 2.8e-69 233.6 0.1 4.1e-54 183.8 0.0 2.0 2 0 0 2 2 2 2 Ferrochelatase FoP_duplication PF13865.6 CBZ25508.1 - 0.15 12.6 0.3 0.27 11.8 0.3 1.4 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 PPR_2 PF13041.6 CBZ25509.1 - 9.8e-48 160.1 9.0 1.8e-07 31.2 0.0 13.2 7 4 7 14 14 14 9 PPR repeat family PPR PF01535.20 CBZ25509.1 - 3.6e-38 127.1 21.2 0.0005 20.1 0.1 17.2 18 0 0 18 18 18 9 PPR repeat PPR_3 PF13812.6 CBZ25509.1 - 4.4e-21 74.7 5.2 9e-05 22.5 0.0 8.6 7 2 2 10 10 10 5 Pentatricopeptide repeat domain PPR_1 PF12854.7 CBZ25509.1 - 8.4e-14 51.0 16.1 0.071 12.8 0.0 12.2 14 0 0 14 14 14 4 PPR repeat PPR_long PF17177.4 CBZ25509.1 - 2.1e-11 43.6 0.1 0.009 15.4 0.1 5.4 2 1 4 6 6 6 4 Pentacotripeptide-repeat region of PRORP ERAP1_C PF11838.8 CBZ25509.1 - 8.9e-06 25.5 1.2 0.26 10.8 0.0 5.2 3 1 3 6 6 6 2 ERAP1-like C-terminal domain TPR_14 PF13428.6 CBZ25509.1 - 5.1e-05 23.8 2.1 3.1 8.9 0.2 6.0 4 1 1 5 5 5 1 Tetratricopeptide repeat RNA_pol_Rpb4 PF03874.16 CBZ25509.1 - 0.0013 19.1 0.0 1.8 8.9 0.0 3.8 4 0 0 4 4 4 1 RNA polymerase Rpb4 ECSIT PF06239.11 CBZ25509.1 - 0.037 13.1 0.1 6.7 5.8 0.0 3.4 2 1 0 2 2 2 0 Evolutionarily conserved signalling intermediate in Toll pathway CT_C_D PF02682.16 CBZ25509.1 - 0.05 13.3 0.0 7 6.3 0.0 2.5 2 0 0 2 2 2 0 Carboxyltransferase domain, subdomain C and D TPR_19 PF14559.6 CBZ25509.1 - 0.71 10.4 6.3 95 3.6 0.0 4.4 3 1 1 4 4 4 0 Tetratricopeptide repeat MDD_C PF18376.1 CBZ25510.1 - 5e-53 179.6 0.0 8.5e-53 178.9 0.0 1.4 1 0 0 1 1 1 1 Mevalonate 5-diphosphate decarboxylase C-terminal domain GHMP_kinases_N PF00288.26 CBZ25510.1 - 3.2e-06 27.3 3.5 6.6e-06 26.3 3.5 1.6 1 0 0 1 1 1 1 GHMP kinases N terminal domain RNaseH_C PF09293.10 CBZ25510.1 - 0.055 13.8 0.2 0.16 12.3 0.2 1.8 1 1 0 1 1 1 0 T4 RNase H, C terminal RRM_1 PF00076.22 CBZ25511.1 - 4.7e-07 29.5 0.0 7.8e-07 28.8 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) MFS_1 PF07690.16 CBZ25512.1 - 6.8e-20 71.3 50.6 8.1e-20 71.0 49.1 1.9 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 CBZ25512.1 - 6.7e-09 35.1 16.5 6.7e-09 35.1 16.5 2.7 1 1 2 3 3 3 1 Sugar (and other) transporter OATP PF03137.20 CBZ25512.1 - 2.4e-08 32.7 25.6 0.00083 17.8 4.2 3.5 2 2 2 4 4 4 3 Organic Anion Transporter Polypeptide (OATP) family MFS_4 PF06779.14 CBZ25512.1 - 1.9e-05 24.2 20.7 1.9e-05 24.2 20.7 1.8 2 1 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB zf-C2HC_2 PF13913.6 CBZ25515.1 - 1.6e-39 133.1 63.2 2.3e-09 36.9 2.2 9.3 10 1 1 11 11 11 6 zinc-finger of a C2HC-type DZR PF12773.7 CBZ25515.1 - 1.6e-14 53.6 59.3 1.1e-11 44.6 10.5 8.6 6 3 0 6 6 6 3 Double zinc ribbon zinc_ribbon_15 PF17032.5 CBZ25515.1 - 9.9e-07 29.4 35.1 0.18 12.6 1.4 7.7 8 0 0 8 8 8 4 zinc-ribbon family zf-ribbon_3 PF13248.6 CBZ25515.1 - 8.4e-05 21.8 10.3 0.00068 18.9 1.2 9.8 10 0 0 10 10 10 3 zinc-ribbon domain zinc_ribbon_2 PF13240.6 CBZ25515.1 - 0.0029 17.3 57.8 0.0095 15.6 1.8 9.2 8 1 1 9 9 9 3 zinc-ribbon domain NOB1_Zn_bind PF08772.11 CBZ25515.1 - 0.003 17.7 33.5 0.0038 17.4 0.2 6.4 6 1 1 7 7 7 3 Nin one binding (NOB1) Zn-ribbon like zf-CpG_bind_C PF12269.8 CBZ25515.1 - 0.0039 17.0 12.5 10 5.8 0.0 6.3 7 0 0 7 7 7 2 CpG binding protein zinc finger C terminal domain zinc-ribbons_6 PF07191.12 CBZ25515.1 - 0.026 14.5 0.5 0.024 14.6 3.2 8.4 9 1 1 10 10 10 0 zinc-ribbons OTT_1508_deam PF14441.6 CBZ25515.1 - 0.083 12.9 3.1 12 6.0 0.2 3.0 2 0 0 2 2 2 0 OTT_1508-like deaminase c-SKI_SMAD_bind PF08782.10 CBZ25515.1 - 0.37 11.1 12.7 5.5 7.3 0.0 5.9 5 1 1 6 6 6 0 c-SKI Smad4 binding domain Rad50_zn_hook PF04423.14 CBZ25515.1 - 1.5 8.7 24.6 0.65 9.9 0.2 6.1 7 0 0 7 7 6 0 Rad50 zinc hook motif zf-RING_7 PF02591.15 CBZ25515.1 - 4.2 7.6 29.5 31 4.9 0.1 8.8 9 0 0 9 9 9 0 C4-type zinc ribbon domain 3Beta_HSD PF01073.19 CBZ25516.1 - 2.7e-10 39.7 0.0 3.9e-10 39.2 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 CBZ25516.1 - 2.9e-06 27.3 0.0 5.7e-06 26.3 0.0 1.5 1 0 0 1 1 1 1 NAD(P)H-binding Semialdhyde_dh PF01118.24 CBZ25516.1 - 3.3e-05 24.3 0.0 7e-05 23.2 0.0 1.6 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Epimerase PF01370.21 CBZ25516.1 - 5.4e-05 22.8 0.0 0.00012 21.6 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 CBZ25516.1 - 0.00058 19.0 0.0 0.23 10.5 0.0 3.0 2 1 0 2 2 2 2 RmlD substrate binding domain NmrA PF05368.13 CBZ25516.1 - 0.0038 16.8 0.0 0.0059 16.2 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family DapB_N PF01113.20 CBZ25516.1 - 0.048 13.8 0.0 0.081 13.0 0.0 1.4 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus KR PF08659.10 CBZ25516.1 - 0.081 12.8 0.0 0.16 11.9 0.0 1.4 1 0 0 1 1 1 0 KR domain Glyco_hydro_31 PF01055.26 CBZ25517.1 - 2.6e-141 471.8 2.5 3.7e-141 471.3 2.5 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.6 CBZ25517.1 - 3.1e-18 65.9 0.2 3.8e-17 62.4 0.1 2.7 2 0 0 2 2 2 1 Galactose mutarotase-like DUF5110 PF17137.4 CBZ25517.1 - 7.2e-07 29.4 0.2 1.6e-06 28.3 0.2 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF5110) Arg_decarbox_C PF17944.1 CBZ25518.1 - 0.046 14.3 0.2 0.16 12.6 0.1 1.9 2 0 0 2 2 2 0 Arginine decarboxylase C-terminal helical extension DUF726 PF05277.12 CBZ25519.1 - 1.5e-54 185.2 26.0 1.1e-52 179.1 0.0 3.2 2 1 1 3 3 3 2 Protein of unknown function (DUF726) VirJ PF06057.11 CBZ25519.1 - 0.05 13.5 0.0 7.9 6.3 0.0 2.3 2 0 0 2 2 2 0 Bacterial virulence protein (VirJ) MHC2-interact PF09307.10 CBZ25519.1 - 0.062 13.3 0.2 0.16 12.0 0.2 1.6 1 0 0 1 1 1 0 CLIP, MHC2 interacting DUF21 PF01595.20 CBZ25521.1 - 2.4e-31 108.8 0.4 4.9e-31 107.8 0.4 1.4 1 0 0 1 1 1 1 Cyclin M transmembrane N-terminal domain CBS PF00571.28 CBZ25521.1 - 4.3e-06 27.1 0.5 0.013 15.9 0.0 3.8 4 0 0 4 4 4 2 CBS domain cNMP_binding PF00027.29 CBZ25521.1 - 0.0091 16.1 0.0 0.02 14.9 0.0 1.5 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain DUF21 PF01595.20 CBZ25522.1 - 1.6e-38 132.2 0.1 3.5e-38 131.1 0.1 1.6 1 0 0 1 1 1 1 Cyclin M transmembrane N-terminal domain Metallophos PF00149.28 CBZ25523.1 - 5e-30 105.5 0.3 8e-30 104.9 0.3 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase PPP5 PF08321.12 CBZ25523.1 - 1.5e-21 76.5 0.8 8.6e-21 74.0 0.1 2.2 2 0 0 2 2 2 1 PPP5 TPR repeat region TPR_1 PF00515.28 CBZ25523.1 - 5.5e-17 60.8 2.9 6.4e-05 22.6 0.1 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 CBZ25523.1 - 1.3e-14 53.0 4.3 0.00038 20.3 0.1 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_8 PF13181.6 CBZ25523.1 - 4.9e-10 38.8 2.4 0.031 14.5 0.1 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.6 CBZ25523.1 - 1.9e-09 37.0 0.4 4.1e-05 23.2 0.0 2.9 2 1 0 2 2 2 2 TPR repeat TPR_16 PF13432.6 CBZ25523.1 - 1.9e-05 25.2 0.8 0.064 13.9 0.1 2.9 2 1 2 4 4 4 3 Tetratricopeptide repeat TPR_17 PF13431.6 CBZ25523.1 - 3.8e-05 23.8 0.4 0.0004 20.6 0.0 2.7 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 CBZ25523.1 - 4.8e-05 23.8 0.9 0.043 14.6 0.1 3.2 1 1 2 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.6 CBZ25523.1 - 0.00098 19.6 1.2 0.0046 17.4 0.5 2.1 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_9 PF13371.6 CBZ25523.1 - 0.045 13.9 0.1 2 8.6 0.0 2.3 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.6 CBZ25523.1 - 0.084 12.9 0.1 22 5.4 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.6 CBZ25523.1 - 0.085 13.2 3.8 19 5.6 0.1 3.1 1 1 2 3 3 3 0 Tetratricopeptide repeat Lipase_3 PF01764.25 CBZ25524.1 - 3e-12 46.6 0.0 5.6e-12 45.7 0.0 1.5 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.7 CBZ25524.1 - 0.00031 21.4 0.3 0.00077 20.1 0.0 1.9 2 0 0 2 2 2 1 Alpha/beta hydrolase family RRM_1 PF00076.22 CBZ25525.1 - 4.7e-28 96.8 0.0 8.5e-17 60.7 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CBZ25525.1 - 0.00031 20.8 0.0 0.89 9.7 0.0 2.7 2 0 0 2 2 2 2 RNA recognition motif RRM_5 PF13893.6 CBZ25525.1 - 0.0014 18.2 0.0 0.044 13.4 0.0 2.5 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 CBZ25525.1 - 0.031 14.3 0.0 4.7 7.3 0.0 2.4 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif Limkain-b1 PF11608.8 CBZ25525.1 - 0.11 12.6 0.0 0.45 10.6 0.0 2.1 2 0 0 2 2 2 0 Limkain b1 RRM_1 PF00076.22 CBZ25526.1 - 3.9e-28 97.1 0.0 8.5e-17 60.7 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CBZ25526.1 - 0.00032 20.8 0.0 0.8 9.9 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif RRM_5 PF13893.6 CBZ25526.1 - 0.0028 17.3 0.0 0.063 12.9 0.0 2.2 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 CBZ25526.1 - 0.031 14.3 0.0 4.7 7.3 0.0 2.4 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif PHM7_cyt PF14703.6 CBZ25526.1 - 0.082 13.1 0.2 42 4.3 0.0 3.1 2 1 1 3 3 3 0 Cytosolic domain of 10TM putative phosphate transporter Limkain-b1 PF11608.8 CBZ25526.1 - 0.11 12.5 0.0 0.45 10.6 0.0 2.1 2 0 0 2 2 2 0 Limkain b1 RRM_1 PF00076.22 CBZ25527.1 - 1.9e-31 107.7 0.0 8.8e-19 67.1 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 CBZ25527.1 - 2e-05 24.5 0.0 0.03 14.3 0.0 2.3 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif RRM_7 PF16367.5 CBZ25527.1 - 0.044 13.9 0.0 0.15 12.2 0.0 1.8 2 1 0 2 2 2 0 RNA recognition motif SET_assoc PF11767.8 CBZ25527.1 - 0.11 12.2 0.0 0.93 9.2 0.0 2.2 2 0 0 2 2 2 0 Histone lysine methyltransferase SET associated Amino_oxidase PF01593.24 CBZ25528.1 - 4.4e-10 39.4 0.0 1.9e-09 37.4 0.0 1.8 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 CBZ25528.1 - 3.1e-07 30.5 1.4 8.9e-07 29.0 0.2 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 CBZ25528.1 - 0.0098 15.1 0.1 0.032 13.4 0.1 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 CBZ25528.1 - 0.027 14.4 0.6 0.092 12.7 0.2 2.1 2 0 0 2 2 2 0 FAD-NAD(P)-binding DAO PF01266.24 CBZ25528.1 - 0.041 13.5 0.0 0.097 12.2 0.0 1.8 2 0 0 2 2 2 0 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 CBZ25528.1 - 0.056 12.7 0.3 0.088 12.0 0.3 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 CBZ25528.1 - 0.14 11.4 0.1 0.24 10.6 0.1 1.3 1 0 0 1 1 1 0 Thi4 family Aha1_N PF09229.11 CBZ25529.1 - 1.5e-25 90.0 0.9 2e-25 89.6 0.9 1.2 1 0 0 1 1 1 1 Activator of Hsp90 ATPase, N-terminal AHSA1 PF08327.11 CBZ25529.1 - 2.8e-19 69.6 0.0 9e-19 67.9 0.0 1.9 2 1 1 3 3 3 1 Activator of Hsp90 ATPase homolog 1-like protein Ribosomal_60s PF00428.19 CBZ25529.1 - 0.0057 17.2 0.7 0.0057 17.2 0.7 1.8 2 0 0 2 2 2 1 60s Acidic ribosomal protein RRM_1 PF00076.22 CBZ25530.1 - 9.9e-12 44.5 0.0 1.6e-11 43.9 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Pkinase PF00069.25 CBZ25535.1 - 7.9e-58 195.9 0.0 1e-57 195.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ25535.1 - 5.1e-23 81.7 0.0 8.7e-23 80.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Choline_kinase PF01633.20 CBZ25535.1 - 0.0045 16.6 0.0 0.0079 15.8 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.23 CBZ25535.1 - 0.005 16.8 0.2 0.021 14.7 0.0 2.1 2 1 1 3 3 3 1 Phosphotransferase enzyme family Kdo PF06293.14 CBZ25535.1 - 0.043 13.2 0.0 0.092 12.1 0.0 1.6 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family UDPGT PF00201.18 CBZ25535.1 - 0.18 10.5 0.0 0.27 10.0 0.0 1.2 1 0 0 1 1 1 0 UDP-glucoronosyl and UDP-glucosyl transferase Vir_act_alpha_C PF10400.9 CBZ25536.1 - 0.0097 16.6 4.0 2.5 8.9 0.7 2.8 2 0 0 2 2 2 2 Virulence activator alpha C-term DnaB_bind PF10410.9 CBZ25536.1 - 0.01 16.0 0.7 0.46 10.7 0.1 3.3 3 0 0 3 3 3 0 DnaB-helicase binding domain of primase DUF4404 PF14357.6 CBZ25536.1 - 1.4 9.6 5.6 0.4 11.4 1.8 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4404) CoaE PF01121.20 CBZ25537.1 - 1.5e-22 80.1 0.4 1.7e-06 27.8 0.4 4.1 4 0 0 4 4 4 4 Dephospho-CoA kinase AAA_18 PF13238.6 CBZ25537.1 - 0.083 13.4 0.1 0.19 12.3 0.1 1.6 1 0 0 1 1 1 0 AAA domain NTF2 PF02136.20 CBZ25538.1 - 2.1e-08 34.7 0.0 3.3e-08 34.1 0.0 1.3 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain RRM_1 PF00076.22 CBZ25538.1 - 0.088 12.6 0.0 0.36 10.7 0.0 2.0 1 1 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF4379 PF14311.6 CBZ25540.1 - 2.7e-18 66.1 9.0 8.3e-09 35.7 2.0 3.0 2 1 0 2 2 2 2 Probable Zinc-ribbon domain Zn_Tnp_IS1595 PF12760.7 CBZ25540.1 - 0.0074 16.2 8.5 0.78 9.8 3.0 3.6 3 1 0 3 3 3 1 Transposase zinc-ribbon domain Elf1 PF05129.13 CBZ25540.1 - 0.02 14.9 1.3 3.9 7.6 0.1 3.0 3 0 0 3 3 3 0 Transcription elongation factor Elf1 like DUF5313 PF17240.2 CBZ25540.1 - 0.025 15.0 0.1 0.048 14.1 0.1 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5313) zf-ZPR1 PF03367.13 CBZ25540.1 - 0.033 14.0 0.0 0.084 12.7 0.0 1.7 1 0 0 1 1 1 0 ZPR1 zinc-finger domain zinc_ribbon_10 PF10058.9 CBZ25540.1 - 0.04 13.6 3.5 14 5.5 0.4 3.3 3 0 0 3 3 3 0 Predicted integral membrane zinc-ribbon metal-binding protein VATC PF18716.1 CBZ25540.1 - 0.11 12.3 9.0 0.54 10.2 0.5 3.3 2 1 1 3 3 3 0 Vms1-associating treble clef domain zf-NADH-PPase PF09297.11 CBZ25540.1 - 0.12 12.0 0.6 0.12 12.0 0.6 3.2 3 0 0 3 3 3 0 NADH pyrophosphatase zinc ribbon domain zf-IS66 PF13005.7 CBZ25540.1 - 0.2 12.1 1.8 14 6.1 0.0 3.4 3 0 0 3 3 3 0 zinc-finger binding domain of transposase IS66 zf-Sec23_Sec24 PF04810.15 CBZ25540.1 - 0.47 10.6 10.0 2.5 8.2 0.3 3.7 4 0 0 4 4 4 0 Sec23/Sec24 zinc finger Zn-ribbon_8 PF09723.10 CBZ25540.1 - 0.77 9.9 7.6 15 5.8 0.1 3.1 2 1 0 2 2 2 0 Zinc ribbon domain Rubredoxin_2 PF18073.1 CBZ25540.1 - 1.1 9.1 14.8 1.4 8.7 0.6 3.5 3 0 0 3 3 3 0 Rubredoxin metal binding domain zf-HC5HC2H PF13771.6 CBZ25540.1 - 1.2 9.4 4.7 7.8 6.8 0.6 2.9 3 1 0 3 3 3 0 PHD-like zinc-binding domain HalOD2 PF18547.1 CBZ25540.1 - 1.7 8.6 5.9 17 5.4 0.1 3.5 4 0 0 4 4 4 0 Halobacterial output domain 2 Zn_ribbon_recom PF13408.6 CBZ25540.1 - 4.3 7.9 9.9 8.2 7.0 2.2 2.7 2 1 0 2 2 2 0 Recombinase zinc beta ribbon domain DnaJ PF00226.31 CBZ25541.1 - 6.7e-15 55.0 0.0 1.2e-14 54.1 0.0 1.4 1 0 0 1 1 1 1 DnaJ domain DUF446 PF04287.12 CBZ25541.1 - 0.054 13.6 0.1 0.1 12.7 0.1 1.4 1 0 0 1 1 1 0 tRNA pseudouridine synthase C DUF2615 PF11027.8 CBZ25541.1 - 0.16 12.1 0.1 0.3 11.2 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2615) DUF535 PF04393.13 CBZ25541.1 - 0.31 10.2 1.1 0.52 9.5 0.3 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF535) FAM221 PF14753.6 CBZ25542.1 - 2e-13 50.4 20.3 2.9e-12 46.6 2.6 3.5 4 0 0 4 4 4 3 Protein FAM221A/B NOB1_Zn_bind PF08772.11 CBZ25542.1 - 0.0098 16.0 1.3 0.0098 16.0 1.3 3.0 3 0 0 3 3 3 1 Nin one binding (NOB1) Zn-ribbon like DUF2616 PF11077.8 CBZ25542.1 - 0.14 11.8 4.8 0.36 10.5 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2616) ATP12 PF07542.11 CBZ25543.1 - 2e-19 70.0 0.0 4.2e-19 68.9 0.0 1.6 1 0 0 1 1 1 1 ATP12 chaperone protein DUF1654 PF07867.11 CBZ25543.1 - 0.16 11.7 0.2 0.29 10.9 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1654) Peptidase_C13 PF01650.18 CBZ25544.1 - 1.2e-39 136.4 0.1 1.7e-39 135.9 0.1 1.1 1 0 0 1 1 1 1 Peptidase C13 family TTL PF03133.15 CBZ25545.1 - 1.5e-76 257.3 0.0 2.1e-76 256.9 0.0 1.1 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 CBZ25545.1 - 4.1e-05 23.0 0.0 0.0018 17.6 0.0 2.8 3 0 0 3 3 3 1 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 CBZ25545.1 - 0.0044 16.3 0.0 0.019 14.2 0.0 2.0 2 0 0 2 2 2 1 Sugar-transfer associated ATP-grasp DUF3884 PF13024.6 CBZ25545.1 - 0.099 12.2 0.0 0.25 10.9 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3884) Nuc_sug_transp PF04142.15 CBZ25548.1 - 3.7e-69 233.3 13.9 8.4e-62 209.1 5.6 2.5 2 1 0 2 2 2 2 Nucleotide-sugar transporter EamA PF00892.20 CBZ25548.1 - 3.2e-06 27.4 5.3 3.2e-06 27.4 5.3 3.5 3 0 0 3 3 3 2 EamA-like transporter family PUNUT PF16913.5 CBZ25548.1 - 0.00062 19.1 8.7 0.0013 18.1 2.3 3.1 3 0 0 3 3 3 1 Purine nucleobase transmembrane transport TPT PF03151.16 CBZ25548.1 - 0.0015 17.9 0.3 0.0015 17.9 0.3 2.7 3 0 0 3 3 3 2 Triose-phosphate Transporter family PAP2 PF01569.21 CBZ25551.1 - 9.5e-18 64.3 0.5 1.5e-17 63.6 0.5 1.2 1 0 0 1 1 1 1 PAP2 superfamily PAP2 PF01569.21 CBZ25552.1 - 4.4e-22 78.3 4.7 4.4e-22 78.3 4.7 2.0 2 1 0 2 2 2 1 PAP2 superfamily PAP2_3 PF14378.6 CBZ25552.1 - 0.0048 16.6 3.8 0.0048 16.6 3.8 2.7 2 1 0 2 2 2 1 PAP2 superfamily Peptidase_S10 PF00450.22 CBZ25553.1 - 1.2e-108 364.2 0.2 1.5e-108 363.9 0.2 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Ubiquitin_2 PF14560.6 CBZ25554.1 - 6e-24 84.3 0.0 1.1e-23 83.5 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-like domain CAP_GLY PF01302.25 CBZ25554.1 - 3.2e-20 71.9 0.5 6.2e-20 71.0 0.5 1.5 1 0 0 1 1 1 1 CAP-Gly domain ubiquitin PF00240.23 CBZ25554.1 - 0.0098 15.6 0.0 0.091 12.5 0.0 2.2 1 1 0 1 1 1 1 Ubiquitin family WD40 PF00400.32 CBZ25555.1 - 9e-37 124.5 20.7 1.4e-06 28.9 1.0 7.5 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBZ25555.1 - 1.2e-10 41.6 3.9 0.076 13.3 0.0 5.6 2 1 4 7 7 7 4 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 CBZ25555.1 - 0.0058 15.3 0.6 0.64 8.6 0.0 2.4 1 1 1 2 2 2 2 Nucleoporin Nup120/160 ABC_tran_CTD PF16326.5 CBZ25555.1 - 0.021 15.1 4.1 0.2 11.9 1.0 2.5 2 0 0 2 2 2 0 ABC transporter C-terminal domain PALB2_WD40 PF16756.5 CBZ25555.1 - 0.11 11.4 7.7 1.1 8.1 0.4 2.9 2 1 1 3 3 3 0 Partner and localizer of BRCA2 WD40 domain Cnn_1N PF07989.11 CBZ25555.1 - 0.15 12.2 7.4 4.1 7.6 0.1 2.4 2 0 0 2 2 2 0 Centrosomin N-terminal motif 1 CENP-F_leu_zip PF10473.9 CBZ25555.1 - 3.1 7.8 20.1 5.3 7.1 20.1 1.3 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 UDG PF03167.19 CBZ25556.1 - 3.7e-18 66.0 0.0 5.6e-18 65.4 0.0 1.2 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily BTB_2 PF02214.22 CBZ25557.1 - 9.3e-14 51.6 0.0 1.4e-13 51.0 0.0 1.2 1 0 0 1 1 1 1 BTB/POZ domain Phage_CI_C PF16452.5 CBZ25557.1 - 0.16 12.3 0.0 0.28 11.5 0.0 1.3 1 0 0 1 1 1 0 Bacteriophage CI repressor C-terminal domain PPR_3 PF13812.6 CBZ25558.1 - 5e-05 23.3 0.0 0.14 12.2 0.0 3.3 3 0 0 3 3 3 2 Pentatricopeptide repeat domain PPR_2 PF13041.6 CBZ25558.1 - 0.049 13.8 0.0 3.5 7.9 0.0 2.8 3 0 0 3 3 3 0 PPR repeat family Thyroglob_assoc PF16597.5 CBZ25558.1 - 0.071 13.4 0.5 0.24 11.7 0.0 2.1 2 0 0 2 2 2 0 Thyroglobulin_1 repeat associated disordered domain Aconitase PF00330.20 CBZ25559.1 - 5.1e-180 599.4 0.0 6.8e-180 599.0 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 CBZ25559.1 - 4e-42 143.7 0.0 9.8e-42 142.4 0.0 1.7 1 0 0 1 1 1 1 Aconitase C-terminal domain RT_RNaseH PF17917.1 CBZ25560.1 - 0.046 14.0 0.8 0.97 9.8 0.1 2.4 2 0 0 2 2 2 0 RNase H-like domain found in reverse transcriptase UPF0242 PF06785.11 CBZ25560.1 - 0.33 11.0 14.6 0.89 9.6 7.5 2.7 2 1 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus DUF5593 PF18007.1 CBZ25560.1 - 0.6 10.8 9.8 1.4 9.6 1.3 3.9 3 2 1 4 4 4 0 Domain of unknown function (DUF5593) CASP_C PF08172.12 CBZ25560.1 - 0.87 8.9 13.8 0.064 12.6 7.0 2.4 2 0 0 2 2 2 0 CASP C terminal LemA PF04011.12 CBZ25560.1 - 1.6 8.5 12.5 0.037 13.9 4.5 2.1 2 0 0 2 2 2 0 LemA family FAM220 PF15487.6 CBZ25560.1 - 3.4 7.2 12.0 3.8 7.1 10.2 2.0 2 0 0 2 2 2 0 FAM220 family Lectin_N PF03954.14 CBZ25560.1 - 4.1 7.1 11.0 0.86 9.3 0.4 3.5 2 1 0 2 2 2 0 Hepatic lectin, N-terminal domain GIT_CC PF16559.5 CBZ25560.1 - 4.5 7.2 5.4 34 4.4 0.2 2.7 2 0 0 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor TBCC PF07986.12 CBZ25561.1 - 4.6e-34 116.7 0.1 6.7e-34 116.2 0.1 1.2 1 0 0 1 1 1 1 Tubulin binding cofactor C FOP_dimer PF09398.10 CBZ25561.1 - 0.0018 18.5 0.0 0.0038 17.4 0.0 1.5 1 0 0 1 1 1 1 FOP N terminal dimerisation domain CAP_C PF08603.11 CBZ25561.1 - 0.11 12.1 0.1 0.19 11.3 0.1 1.3 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) C terminal MRI PF15325.6 CBZ25561.1 - 2.1 9.5 13.0 4.7 8.4 8.3 2.8 2 0 0 2 2 2 0 Modulator of retrovirus infection TMEM135_C_rich PF15982.5 CBZ25562.1 - 0.0043 17.7 1.1 0.0043 17.7 1.1 1.9 2 0 0 2 2 2 1 N-terminal cysteine-rich region of Transmembrane protein 135 V-ATPase_C PF03223.15 CBZ25564.1 - 1.7e-83 281.0 0.3 2e-83 280.8 0.3 1.0 1 0 0 1 1 1 1 V-ATPase subunit C ASH PF15780.5 CBZ25565.1 - 5.8e-23 81.0 9.6 0.0065 16.7 0.0 8.3 7 1 0 7 7 7 5 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin DUF1573 PF07610.11 CBZ25565.1 - 3.3e-11 43.1 0.0 0.057 13.4 0.0 7.4 7 1 1 8 8 8 3 Protein of unknown function (DUF1573) PapD-like PF14874.6 CBZ25565.1 - 6.6e-10 39.1 5.0 0.0077 16.4 0.2 4.8 4 0 0 4 4 4 3 Flagellar-associated PapD-like TMEM131_like PF12371.8 CBZ25565.1 - 5e-08 33.1 1.3 0.17 12.2 0.1 5.5 5 0 0 5 5 5 2 Transmembrane protein 131-like Motile_Sperm PF00635.26 CBZ25565.1 - 4.7e-05 23.2 0.2 0.0064 16.3 0.0 3.9 4 0 0 4 4 4 1 MSP (Major sperm protein) domain PapD_N PF00345.20 CBZ25565.1 - 0.0059 16.5 0.0 13 5.7 0.0 4.0 4 0 0 4 4 4 2 Pili and flagellar-assembly chaperone, PapD N-terminal domain MYCBPAP PF14646.6 CBZ25565.1 - 0.034 13.1 0.1 0.2 10.6 0.0 2.3 3 0 0 3 3 3 0 MYCBP-associated protein family ECH_1 PF00378.20 CBZ25566.1 - 1e-36 126.6 0.5 4.7e-34 117.8 0.1 2.1 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 CBZ25566.1 - 2.6e-13 50.2 0.8 1.9e-12 47.4 0.8 2.1 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase RRM_1 PF00076.22 CBZ25567.1 - 3.2e-17 62.1 0.0 6.5e-17 61.1 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CBZ25567.1 - 0.038 14.1 0.1 0.13 12.4 0.0 2.0 2 1 0 2 2 2 0 RNA recognition motif Nup35_RRM_2 PF14605.6 CBZ25567.1 - 0.11 12.5 0.0 0.71 9.9 0.0 2.2 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.11 CBZ25567.1 - 0.16 12.0 0.0 2.1 8.4 0.0 2.2 2 0 0 2 2 2 0 RNA binding motif FYVE PF01363.21 CBZ25569.1 - 1e-19 70.4 8.8 1e-19 70.4 8.8 4.6 3 2 0 3 3 3 1 FYVE zinc finger zf-RanBP PF00641.18 CBZ25569.1 - 9.9e-17 60.0 62.3 1.7e-07 30.4 1.7 6.8 7 0 0 7 7 7 5 Zn-finger in Ran binding protein and others DZR PF12773.7 CBZ25569.1 - 0.0085 16.1 53.0 0.46 10.6 9.3 5.6 2 2 4 6 6 6 5 Double zinc ribbon Vps36-NZF-N PF16988.5 CBZ25569.1 - 0.022 14.2 43.7 0.12 11.7 0.5 6.8 7 2 0 7 7 7 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain Peptidase_M41 PF01434.18 CBZ25570.1 - 1.5e-45 155.4 2.4 2.3e-45 154.8 2.4 1.2 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.29 CBZ25570.1 - 1.7e-39 135.2 0.0 3.2e-39 134.4 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 CBZ25570.1 - 1.2e-06 29.1 0.8 4.8e-06 27.1 0.1 2.3 1 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 CBZ25570.1 - 0.00037 20.8 0.5 0.012 15.9 0.3 2.9 1 1 1 2 2 2 1 AAA domain AAA_5 PF07728.14 CBZ25570.1 - 0.00078 19.5 0.2 0.0062 16.5 0.2 2.4 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 CBZ25570.1 - 0.0017 18.5 0.1 0.0083 16.3 0.1 2.2 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) RuvB_N PF05496.12 CBZ25570.1 - 0.0069 16.1 1.9 0.076 12.8 0.0 3.1 3 1 0 3 3 3 1 Holliday junction DNA helicase RuvB P-loop domain AAA_24 PF13479.6 CBZ25570.1 - 0.0081 15.9 0.0 0.017 14.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 CBZ25570.1 - 0.019 14.3 0.1 1.1 8.6 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin Sigma54_activat PF00158.26 CBZ25570.1 - 0.021 14.5 0.1 0.073 12.8 0.1 2.0 1 1 0 1 1 1 0 Sigma-54 interaction domain AAA_lid_3 PF17862.1 CBZ25570.1 - 0.034 14.0 0.0 0.087 12.7 0.0 1.6 1 0 0 1 1 1 0 AAA+ lid domain TIP49 PF06068.13 CBZ25570.1 - 0.053 12.7 0.0 0.14 11.3 0.0 1.7 2 0 0 2 2 2 0 TIP49 P-loop domain Peptidase_M50B PF13398.6 CBZ25570.1 - 0.056 13.1 0.1 0.11 12.2 0.1 1.4 1 0 0 1 1 1 0 Peptidase M50B-like IstB_IS21 PF01695.17 CBZ25570.1 - 0.058 13.1 0.1 0.12 12.1 0.1 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_14 PF13173.6 CBZ25570.1 - 0.076 13.1 0.0 0.16 12.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain DUF2075 PF09848.9 CBZ25570.1 - 0.099 11.9 0.2 0.15 11.2 0.2 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) NAD_binding_3 PF03447.16 CBZ25570.1 - 0.099 13.3 0.0 0.32 11.6 0.0 1.9 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain ATPase PF06745.13 CBZ25570.1 - 0.1 11.9 0.1 0.27 10.5 0.1 1.6 1 0 0 1 1 1 0 KaiC NACHT PF05729.12 CBZ25570.1 - 0.13 12.2 0.4 0.73 9.7 0.2 2.3 2 0 0 2 2 2 0 NACHT domain Ribosomal_L1 PF00687.21 CBZ25571.1 - 4.1e-41 141.0 2.5 5e-41 140.7 2.5 1.0 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family Pkinase PF00069.25 CBZ25573.1 - 2.9e-75 253.0 0.0 3.3e-75 252.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ25573.1 - 2.6e-39 135.1 0.0 3.1e-39 134.8 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CBZ25573.1 - 8.9e-10 38.4 0.0 1.5e-09 37.6 0.0 1.3 1 1 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 CBZ25573.1 - 4.6e-07 29.1 0.0 1.4e-06 27.5 0.1 1.6 2 0 0 2 2 2 1 Haspin like kinase domain APH PF01636.23 CBZ25573.1 - 1.8e-05 24.8 0.1 0.12 12.3 0.0 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 CBZ25573.1 - 0.0058 16.0 0.1 0.0094 15.3 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Phosducin PF02114.16 CBZ25573.1 - 0.094 11.7 0.1 0.13 11.2 0.1 1.2 1 0 0 1 1 1 0 Phosducin Seadorna_VP7 PF07387.11 CBZ25573.1 - 0.13 11.3 0.0 0.23 10.5 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 DUF421 PF04239.12 CBZ25573.1 - 0.19 11.5 2.0 0.27 11.0 1.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF421) PA26 PF04636.13 CBZ25574.1 - 3.7e-32 111.8 2.4 7.3e-12 44.9 0.1 3.2 3 0 0 3 3 3 3 PA26 p53-induced protein (sestrin) HEAT PF02985.22 CBZ25575.1 - 2.1e-21 74.1 15.0 0.012 15.8 0.0 10.5 11 0 0 11 11 11 6 HEAT repeat HEAT_2 PF13646.6 CBZ25575.1 - 8.2e-14 51.8 17.7 0.0085 16.5 0.0 7.1 4 4 3 7 7 7 5 HEAT repeats HEAT_EZ PF13513.6 CBZ25575.1 - 0.00054 20.4 4.1 0.077 13.5 0.0 4.8 5 0 0 5 5 5 1 HEAT-like repeat Adaptin_N PF01602.20 CBZ25575.1 - 0.0041 15.7 0.4 2.8 6.4 0.1 3.5 1 1 1 5 5 5 2 Adaptin N terminal region DUF2063 PF09836.9 CBZ25575.1 - 0.04 14.2 0.0 0.13 12.5 0.0 1.9 1 0 0 1 1 1 0 Putative DNA-binding domain CLASP_N PF12348.8 CBZ25575.1 - 0.043 13.4 0.0 24 4.4 0.0 3.5 2 1 2 4 4 4 0 CLASP N terminal CW_binding_2 PF04122.12 CBZ25575.1 - 1.6 9.5 4.0 9.8 6.9 4.0 2.3 1 1 0 1 1 1 0 Putative cell wall binding repeat 2 FIVAR PF07554.13 CBZ25575.1 - 5.1 7.9 9.8 0.54 11.1 5.1 1.8 2 0 0 2 2 2 0 FIVAR domain Citrate_synt PF00285.21 CBZ25577.1 - 1.5e-97 326.9 0.0 2.1e-97 326.4 0.0 1.2 1 0 0 1 1 1 1 Citrate synthase, C-terminal domain Cyclin_C PF02984.19 CBZ25577.1 - 0.0041 17.2 0.6 0.074 13.1 0.0 2.5 2 0 0 2 2 2 1 Cyclin, C-terminal domain Citrate_synt PF00285.21 CBZ25578.1 - 1.9e-96 323.3 0.0 2.3e-96 323.0 0.0 1.1 1 0 0 1 1 1 1 Citrate synthase, C-terminal domain Cyclin_C PF02984.19 CBZ25578.1 - 0.0081 16.2 0.9 0.056 13.5 0.0 2.4 2 0 0 2 2 2 1 Cyclin, C-terminal domain Cytomega_gL PF01801.16 CBZ25578.1 - 0.16 11.3 0.0 0.28 10.6 0.0 1.3 1 0 0 1 1 1 0 Cytomegalovirus glycoprotein L AAA_16 PF13191.6 CBZ25580.1 - 0.02 15.3 4.0 0.021 15.2 0.5 2.9 3 1 0 3 3 3 0 AAA ATPase domain DUF4407 PF14362.6 CBZ25580.1 - 0.083 12.2 0.7 0.14 11.5 0.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Seryl_tRNA_N PF02403.22 CBZ25580.1 - 0.2 11.9 0.3 0.44 10.8 0.3 1.4 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain Tctex-1 PF03645.13 CBZ25581.1 - 7e-17 61.5 0.1 1.3e-16 60.6 0.1 1.4 1 0 0 1 1 1 1 Tctex-1 family DUF2457 PF10446.9 CBZ25581.1 - 2.2 7.3 11.8 5.4 6.1 11.6 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2457) GTP_EFTU PF00009.27 CBZ25582.1 - 4.5e-53 179.7 0.2 8.6e-53 178.8 0.2 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 CBZ25582.1 - 1.3e-19 70.5 0.0 2.6e-18 66.4 0.0 2.5 1 1 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 CBZ25582.1 - 1.1e-07 32.2 0.8 2.5e-07 31.0 0.8 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 CBZ25582.1 - 0.0048 17.0 0.0 0.011 15.8 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase PduV-EutP PF10662.9 CBZ25582.1 - 0.074 12.8 0.8 3 7.6 0.8 2.5 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation zf-C2H2_jaz PF12171.8 CBZ25584.1 - 1.6e-06 28.2 0.2 2.8e-06 27.4 0.2 1.4 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 CBZ25584.1 - 0.00013 22.2 0.2 0.0002 21.6 0.2 1.3 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.7 CBZ25584.1 - 0.04 14.2 0.3 0.051 13.9 0.3 1.1 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) PDZ_6 PF17820.1 CBZ25585.1 - 2.3e-05 24.2 0.0 6.3e-05 22.7 0.0 1.8 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 CBZ25585.1 - 0.0014 18.9 0.0 0.0041 17.4 0.0 1.8 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 CBZ25585.1 - 0.19 12.1 0.0 0.48 10.8 0.0 1.6 1 0 0 1 1 1 0 PDZ domain RNA_pol_Rpb5_C PF01191.19 CBZ25586.1 - 1.6e-29 101.5 0.2 3.1e-29 100.6 0.2 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb5, C-terminal domain RNA_pol_Rpb5_N PF03871.14 CBZ25586.1 - 1.2e-22 80.3 0.0 2.6e-22 79.2 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb5, N-terminal domain DUF4892 PF16234.5 CBZ25586.1 - 0.12 11.8 0.0 0.22 10.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4892) RNA_pol_Rpb5_C PF01191.19 CBZ25587.1 - 5.6e-23 80.6 0.0 9.9e-23 79.8 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb5, C-terminal domain RNA_pol_Rpb5_N PF03871.14 CBZ25587.1 - 1.7e-07 31.7 0.0 0.00029 21.4 0.0 2.6 2 0 0 2 2 2 2 RNA polymerase Rpb5, N-terminal domain Ribosomal_S8 PF00410.19 CBZ25588.1 - 1e-07 31.9 0.0 1.6e-07 31.3 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S8 AA_kinase PF00696.28 CBZ25588.1 - 0.043 13.4 0.0 3.8 7.0 0.0 2.2 2 0 0 2 2 2 0 Amino acid kinase family FAM199X PF15814.5 CBZ25588.1 - 0.68 8.9 4.2 0.97 8.4 4.2 1.2 1 0 0 1 1 1 0 Protein family FAM199X CDP-OH_P_transf PF01066.21 CBZ25589.1 - 3.5e-16 59.7 0.1 3.5e-16 59.7 0.1 3.3 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase HEAT_EZ PF13513.6 CBZ25590.1 - 1.5e-07 31.7 11.1 0.037 14.6 1.0 8.3 8 0 0 8 8 8 3 HEAT-like repeat HEAT PF02985.22 CBZ25590.1 - 3e-06 27.0 6.6 0.072 13.4 0.1 8.7 8 0 0 8 8 8 1 HEAT repeat Vac14_Fab1_bd PF12755.7 CBZ25590.1 - 0.014 15.9 0.5 82 3.9 0.0 5.3 5 0 0 5 5 5 0 Vacuolar 14 Fab1-binding region SBF2 PF12335.8 CBZ25590.1 - 0.032 13.8 0.0 0.099 12.2 0.0 1.8 1 0 0 1 1 1 0 Myotubularin protein WD40 PF00400.32 CBZ25591.1 - 1.1e-24 86.2 18.7 3.5e-08 34.0 0.1 11.1 12 0 0 12 12 12 5 WD domain, G-beta repeat Utp12 PF04003.12 CBZ25591.1 - 1.3e-11 44.7 0.1 8.6e-11 42.1 0.0 2.2 2 0 0 2 2 2 1 Dip2/Utp12 Family ANAPC4_WD40 PF12894.7 CBZ25591.1 - 2.3e-11 43.8 0.0 0.062 13.6 0.0 7.0 6 1 0 6 6 6 1 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 CBZ25591.1 - 0.00015 20.8 0.2 0.78 8.6 0.0 3.5 3 0 0 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein DUF1513 PF07433.11 CBZ25591.1 - 0.0026 16.9 1.0 0.24 10.5 0.0 3.0 3 0 0 3 3 3 1 Protein of unknown function (DUF1513) PD40 PF07676.12 CBZ25591.1 - 0.019 14.9 0.7 29 4.8 0.0 4.7 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat Nup160 PF11715.8 CBZ25591.1 - 0.02 13.5 0.0 0.056 12.1 0.0 1.7 1 0 0 1 1 1 0 Nucleoporin Nup120/160 Sporozoite_P67 PF05642.11 CBZ25595.1 - 0.27 9.3 2.3 0.51 8.4 2.3 1.4 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Pro_isomerase PF00160.21 CBZ25596.1 - 1.5e-33 116.3 0.0 1.1e-32 113.5 0.0 2.1 2 0 0 2 2 2 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Ras PF00071.22 CBZ25597.1 - 8.3e-54 181.6 1.4 1.2e-52 177.7 1.4 2.0 1 1 0 1 1 1 1 Ras family Roc PF08477.13 CBZ25597.1 - 4.4e-35 120.5 0.1 8.5e-35 119.6 0.1 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CBZ25597.1 - 3.1e-12 46.3 0.0 3.9e-12 46.0 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 CBZ25597.1 - 3.6e-07 29.8 0.0 4.9e-07 29.3 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 CBZ25597.1 - 2.5e-06 27.6 0.0 5.2e-06 26.5 0.0 1.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 CBZ25597.1 - 3.2e-05 23.6 0.3 0.00085 18.9 0.0 2.1 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain AAA_16 PF13191.6 CBZ25597.1 - 0.0038 17.6 0.2 0.0054 17.1 0.1 1.6 1 1 0 1 1 1 1 AAA ATPase domain RsgA_GTPase PF03193.16 CBZ25597.1 - 0.0044 16.9 0.1 0.081 12.8 0.1 2.4 1 1 2 3 3 3 1 RsgA GTPase AAA_24 PF13479.6 CBZ25597.1 - 0.0077 16.0 0.1 0.047 13.4 0.0 1.9 2 0 0 2 2 2 1 AAA domain cobW PF02492.19 CBZ25597.1 - 0.014 15.0 0.1 3.7 7.1 0.0 2.4 1 1 1 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_22 PF13401.6 CBZ25597.1 - 0.026 14.8 0.0 0.079 13.2 0.0 1.6 1 1 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 CBZ25597.1 - 0.032 14.1 0.0 0.051 13.5 0.0 1.3 1 0 0 1 1 1 0 NTPase PduV-EutP PF10662.9 CBZ25597.1 - 0.048 13.4 0.0 0.13 12.0 0.0 1.8 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_5 PF07728.14 CBZ25597.1 - 0.048 13.6 0.0 0.066 13.2 0.0 1.4 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) NACHT PF05729.12 CBZ25597.1 - 0.052 13.5 0.0 0.088 12.7 0.0 1.4 1 0 0 1 1 1 0 NACHT domain AAA_7 PF12775.7 CBZ25597.1 - 0.06 12.9 0.0 0.094 12.2 0.0 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region RNA_helicase PF00910.22 CBZ25597.1 - 0.086 13.2 0.0 0.35 11.3 0.0 2.0 1 1 0 1 1 1 0 RNA helicase Glyco_trans_1_4 PF13692.6 CBZ25598.1 - 0.00088 19.7 0.0 0.0052 17.2 0.0 2.4 1 1 0 1 1 1 1 Glycosyl transferases group 1 T2SSE_N PF05157.15 CBZ25598.1 - 0.23 11.8 0.6 2.3 8.5 0.1 2.8 4 0 0 4 4 4 0 Type II secretion system (T2SS), protein E, N-terminal domain PPR_2 PF13041.6 CBZ25599.1 - 0.00012 22.2 0.0 0.12 12.6 0.0 3.1 2 1 1 3 3 3 2 PPR repeat family PPR_3 PF13812.6 CBZ25599.1 - 0.00093 19.2 0.0 0.11 12.6 0.0 2.7 2 1 0 2 2 2 1 Pentatricopeptide repeat domain PPR_long PF17177.4 CBZ25599.1 - 0.0033 16.8 1.0 0.013 14.9 0.4 2.2 1 1 1 2 2 2 1 Pentacotripeptide-repeat region of PRORP GHMP_kinases_C PF08544.13 CBZ25599.1 - 0.13 12.6 0.3 18 5.8 0.0 3.3 2 1 0 2 2 2 0 GHMP kinases C terminal ANAPC4_WD40 PF12894.7 CBZ25600.1 - 0.00033 20.9 0.7 16 5.9 0.1 4.5 3 1 1 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 CBZ25600.1 - 0.0036 18.1 20.5 0.4 11.6 1.7 6.0 7 0 0 7 7 7 3 WD domain, G-beta repeat PD40 PF07676.12 CBZ25600.1 - 0.0036 17.2 0.0 0.74 9.8 0.0 3.4 3 0 0 3 3 3 1 WD40-like Beta Propeller Repeat Myosin_TH1 PF06017.13 CBZ25601.1 - 0.0019 17.9 0.0 0.0031 17.2 0.0 1.2 1 0 0 1 1 1 1 Unconventional myosin tail, actin- and lipid-binding GAS PF13851.6 CBZ25601.1 - 7 5.9 19.5 0.06 12.7 3.9 2.2 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding Nrap_D5 PF17406.2 CBZ25602.1 - 7.4e-30 103.9 0.0 1.5e-29 102.8 0.0 1.5 1 0 0 1 1 1 1 Nrap protein PAP/OAS1-like domain 5 Nrap_D4 PF17405.2 CBZ25602.1 - 3e-17 62.7 0.0 6.5e-17 61.6 0.0 1.5 1 0 0 1 1 1 1 Nrap protein nucleotidyltransferase domain 4 Nrap_D3 PF17404.2 CBZ25602.1 - 8.6e-16 58.4 0.0 1.9e-15 57.3 0.0 1.6 1 0 0 1 1 1 1 Nrap protein domain 3 Nrap_D2 PF17403.2 CBZ25602.1 - 8.7e-06 25.6 0.0 0.00046 20.0 0.0 2.8 3 0 0 3 3 3 1 Nrap protein PAP/OAS-like domain Nrap PF03813.14 CBZ25602.1 - 0.012 15.7 0.0 4.7 7.2 0.0 2.5 2 0 0 2 2 2 0 Nrap protein domain 1 Mannosyl_trans2 PF04188.13 CBZ25604.1 - 6.4e-33 114.7 28.1 2.7e-21 76.4 11.2 4.1 4 0 0 4 4 4 4 Mannosyltransferase (PIG-V) Cnl2_NKP2 PF09447.10 CBZ25605.1 - 0.57 10.4 5.2 12 6.2 0.2 2.8 3 0 0 3 3 3 0 Cnl2/NKP2 family protein IQ PF00612.27 CBZ25605.1 - 0.79 9.7 4.2 12 6.0 0.0 3.0 2 0 0 2 2 2 0 IQ calmodulin-binding motif DUF760 PF05542.11 CBZ25606.1 - 0.23 11.8 2.0 0.84 10.0 0.6 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF760) FUSC PF04632.12 CBZ25606.1 - 0.51 8.8 5.2 0.61 8.6 5.2 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family APG6_N PF17675.1 CBZ25606.1 - 0.77 10.3 16.5 1.8 9.1 15.8 1.8 1 1 0 1 1 1 0 Apg6 coiled-coil region DUF4407 PF14362.6 CBZ25606.1 - 0.94 8.8 12.6 1.2 8.4 12.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Seryl_tRNA_N PF02403.22 CBZ25606.1 - 3.6 7.8 15.8 1.5 9.1 10.5 2.4 1 1 2 3 3 3 0 Seryl-tRNA synthetase N-terminal domain UDPGP PF01704.18 CBZ25607.1 - 1.5e-114 382.9 0.0 2.6e-114 382.1 0.0 1.3 1 1 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase Sigma70_ECF PF07638.11 CBZ25607.1 - 0.13 12.1 0.0 0.24 11.3 0.0 1.4 1 0 0 1 1 1 0 ECF sigma factor Mito_carr PF00153.27 CBZ25608.1 - 1.9e-17 63.0 4.9 1.8e-07 31.0 0.0 3.6 3 1 0 3 3 3 3 Mitochondrial carrier protein Form_Nir_trans PF01226.17 CBZ25608.1 - 0.069 12.5 0.4 11 5.2 0.1 2.4 2 0 0 2 2 2 0 Formate/nitrite transporter Robl_LC7 PF03259.17 CBZ25609.1 - 2.2e-21 75.4 0.0 2.5e-21 75.3 0.0 1.0 1 0 0 1 1 1 1 Roadblock/LC7 domain LAMTOR5 PF16672.5 CBZ25609.1 - 0.025 14.5 0.0 0.036 14.0 0.0 1.2 1 0 0 1 1 1 0 Ragulator complex protein LAMTOR5 NikR_C PF08753.11 CBZ25609.1 - 0.1 12.8 0.0 0.54 10.4 0.0 2.1 2 0 0 2 2 2 0 NikR C terminal nickel binding domain EzrA PF06160.12 CBZ25610.1 - 2.6 6.1 12.0 0.14 10.3 4.3 2.1 2 0 0 2 2 2 0 Septation ring formation regulator, EzrA PhoD PF09423.10 CBZ25611.1 - 4e-09 36.0 1.9 5.6e-06 25.6 1.5 3.0 2 1 0 2 2 2 2 PhoD-like phosphatase Hydantoinase_B PF02538.14 CBZ25612.1 - 4.9e-196 652.1 2.8 7.9e-196 651.4 2.8 1.2 1 0 0 1 1 1 1 Hydantoinase B/oxoprolinase Hydantoinase_A PF01968.18 CBZ25612.1 - 7.5e-94 314.2 0.6 2.3e-93 312.6 0.6 1.9 1 0 0 1 1 1 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.13 CBZ25612.1 - 3.9e-51 173.3 0.5 1.9e-49 167.8 0.1 2.6 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase N-terminal region Peptidase_M15_3 PF08291.11 CBZ25612.1 - 0.15 12.2 0.0 0.38 10.9 0.0 1.7 1 0 0 1 1 1 0 Peptidase M15 Peptidase_C2 PF00648.21 CBZ25614.1 - 1.9e-19 69.8 0.0 1e-18 67.4 0.0 1.9 1 1 0 1 1 1 1 Calpain family cysteine protease SRP14 PF02290.15 CBZ25614.1 - 0.04 14.3 0.0 0.094 13.1 0.0 1.6 1 0 0 1 1 1 0 Signal recognition particle 14kD protein Vps16_C PF04840.12 CBZ25615.1 - 1.5e-23 83.4 0.1 1.1e-11 44.4 0.0 2.2 2 0 0 2 2 2 2 Vps16, C-terminal region Vps16_N PF04841.13 CBZ25615.1 - 2.8e-22 79.1 0.0 2e-20 72.9 0.0 2.7 2 1 0 2 2 2 2 Vps16, N-terminal region Pkinase PF00069.25 CBZ25616.1 - 3e-73 246.5 0.0 3.5e-73 246.2 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ25616.1 - 1.5e-36 126.0 0.0 1.8e-36 125.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CBZ25616.1 - 6.4e-07 29.0 0.0 8.5e-07 28.6 0.0 1.3 1 1 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 CBZ25616.1 - 0.0011 17.8 0.0 0.011 14.5 0.0 1.9 2 0 0 2 2 2 1 Fungal protein kinase APH PF01636.23 CBZ25616.1 - 0.042 13.8 0.0 0.12 12.3 0.0 1.5 1 1 0 1 1 1 0 Phosphotransferase enzyme family Haspin_kinase PF12330.8 CBZ25616.1 - 0.093 11.6 0.1 0.13 11.1 0.1 1.2 1 0 0 1 1 1 0 Haspin like kinase domain PDEase_I PF00233.19 CBZ25617.1 - 9e-78 261.3 0.1 9e-78 261.3 0.1 2.3 3 0 0 3 3 3 1 3'5'-cyclic nucleotide phosphodiesterase Ank_5 PF13857.6 CBZ25618.1 - 6.8e-20 70.9 0.3 2.6e-06 27.6 0.0 4.3 2 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank_2 PF12796.7 CBZ25618.1 - 9.1e-20 71.0 0.6 5.2e-11 43.0 0.0 2.8 1 1 2 3 3 3 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 CBZ25618.1 - 2.9e-18 64.1 0.1 1e-05 25.5 0.0 4.2 4 0 0 4 4 4 3 Ankyrin repeat Ank_4 PF13637.6 CBZ25618.1 - 2.4e-17 63.1 0.3 3.3e-11 43.5 0.1 4.1 4 1 1 5 5 5 3 Ankyrin repeats (many copies) Ank PF00023.30 CBZ25618.1 - 1.3e-14 53.8 0.1 5e-05 23.6 0.0 3.4 3 0 0 3 3 3 3 Ankyrin repeat Pheromone PF08015.11 CBZ25618.1 - 0.69 11.0 3.0 17 6.5 3.0 2.4 1 1 0 1 1 1 0 Fungal mating-type pheromone Methyltr_RsmB-F PF01189.17 CBZ25619.1 - 4.4e-35 121.2 0.0 8e-34 117.0 0.0 2.2 2 0 0 2 2 2 1 16S rRNA methyltransferase RsmB/F FtsJ PF01728.19 CBZ25619.1 - 0.00081 19.5 0.0 0.0016 18.6 0.0 1.4 1 0 0 1 1 1 1 FtsJ-like methyltransferase zf-AN1 PF01428.16 CBZ25620.1 - 3.4e-16 59.1 31.7 4.6e-09 36.3 10.2 2.9 2 1 1 3 3 3 2 AN1-like Zinc finger Transp_Tc5_C PF04236.15 CBZ25620.1 - 0.00016 22.0 19.6 0.019 15.3 4.0 2.7 2 0 0 2 2 2 2 Tc5 transposase C-terminal domain IBR PF01485.21 CBZ25620.1 - 0.27 11.5 22.9 0.087 13.1 4.8 2.9 3 0 0 3 3 3 0 IBR domain, a half RING-finger domain Ras PF00071.22 CBZ25621.1 - 9.7e-52 174.8 0.0 2.4e-51 173.6 0.0 1.6 1 1 0 1 1 1 1 Ras family Roc PF08477.13 CBZ25621.1 - 1.1e-31 109.5 0.0 5.5e-20 71.8 0.0 2.1 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CBZ25621.1 - 1.7e-10 40.7 0.0 3.3e-09 36.5 0.0 2.0 1 1 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 CBZ25621.1 - 0.00028 20.3 0.0 0.00037 19.9 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_24 PF13479.6 CBZ25621.1 - 0.0037 17.0 0.1 0.022 14.5 0.0 1.9 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.23 CBZ25621.1 - 0.032 14.3 0.0 0.086 12.9 0.0 1.7 1 1 0 1 1 1 0 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 CBZ25621.1 - 0.041 13.8 0.3 0.39 10.6 0.0 2.1 2 0 0 2 2 2 0 RsgA GTPase Sigma54_activat PF00158.26 CBZ25621.1 - 0.043 13.5 0.0 0.091 12.5 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain DUF1327 PF07041.11 CBZ25621.1 - 0.081 12.9 0.1 0.14 12.2 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1327) ABC_tran PF00005.27 CBZ25621.1 - 0.083 13.4 0.1 0.12 12.9 0.1 1.5 1 1 0 1 1 1 0 ABC transporter AAA_22 PF13401.6 CBZ25621.1 - 0.13 12.5 0.1 0.41 10.9 0.1 2.0 1 1 0 1 1 1 0 AAA domain MSG PF02349.15 CBZ25622.1 - 0.08 13.1 0.6 0.25 11.5 0.6 2.0 1 0 0 1 1 1 0 Major surface glycoprotein zf-C3HC4_3 PF13920.6 CBZ25623.1 - 3e-16 59.0 11.0 5.4e-16 58.2 11.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CBZ25623.1 - 6e-07 29.7 12.8 1.2e-06 28.7 12.8 1.5 1 0 0 1 1 1 1 Ring finger domain Prok-RING_4 PF14447.6 CBZ25623.1 - 1.5e-06 28.0 12.5 3.1e-06 26.9 12.5 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 CBZ25623.1 - 0.00066 19.5 15.6 0.0012 18.6 15.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CBZ25623.1 - 0.018 15.0 11.6 0.037 14.0 11.6 1.6 1 0 0 1 1 1 0 zinc-RING finger domain zinc_ribbon_2 PF13240.6 CBZ25623.1 - 0.027 14.2 0.5 0.071 12.9 0.5 1.8 1 0 0 1 1 1 0 zinc-ribbon domain zf-C4H2 PF10146.9 CBZ25623.1 - 0.084 13.2 11.9 0.77 10.0 11.9 2.2 1 1 0 1 1 1 0 Zinc finger-containing protein zf-P11 PF03854.14 CBZ25623.1 - 0.12 12.0 9.9 0.3 10.8 9.9 1.7 1 1 0 1 1 1 0 P-11 zinc finger SOG2 PF10428.9 CBZ25623.1 - 0.58 9.3 7.1 0.75 8.9 7.1 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein zf-RING_10 PF16685.5 CBZ25623.1 - 3.1 8.0 10.5 9.5 6.4 10.5 1.8 1 0 0 1 1 1 0 zinc RING finger of MSL2 TPR_7 PF13176.6 CBZ25624.1 - 0.13 12.4 0.2 0.29 11.3 0.2 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat Cmc1 PF08583.10 CBZ25625.1 - 0.0059 16.6 2.3 0.013 15.4 2.3 1.6 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like NPV_P10 PF05531.12 CBZ25626.1 - 0.4 11.2 5.9 0.26 11.8 1.2 2.9 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF2196 PF09962.9 CBZ25627.1 - 0.038 14.0 0.1 0.085 12.9 0.1 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2196) Complex1_LYR PF05347.15 CBZ25628.1 - 1.7e-11 44.0 2.1 1.7e-11 44.0 2.1 1.7 2 0 0 2 2 2 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 CBZ25628.1 - 0.016 15.9 0.9 0.043 14.6 0.9 1.8 1 0 0 1 1 1 0 Complex1_LYR-like LCE PF14672.6 CBZ25628.1 - 0.48 11.1 5.9 2 9.1 0.9 2.9 1 1 1 3 3 3 0 Late cornified envelope ProRS-C_1 PF09180.11 CBZ25629.1 - 8.5e-25 86.8 2.4 8.5e-25 86.8 2.4 2.0 2 0 0 2 2 2 1 Prolyl-tRNA synthetase, C-terminal tRNA-synt_2b PF00587.25 CBZ25629.1 - 2.4e-17 63.5 0.0 4.1e-17 62.7 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) tRNA_edit PF04073.15 CBZ25629.1 - 4.4e-17 62.3 0.1 8.2e-17 61.4 0.1 1.5 1 0 0 1 1 1 1 Aminoacyl-tRNA editing domain HGTP_anticodon PF03129.20 CBZ25629.1 - 2.4e-15 56.4 0.0 1e-14 54.4 0.0 2.1 2 0 0 2 2 2 1 Anticodon binding domain EccE PF11203.8 CBZ25629.1 - 5.6 7.4 7.4 5.6 7.4 2.4 3.0 3 0 0 3 3 3 0 Putative type VII ESX secretion system translocon, EccE ProRS-C_1 PF09180.11 CBZ25630.1 - 8.3e-25 86.8 2.4 8.3e-25 86.8 2.4 1.9 2 0 0 2 2 2 1 Prolyl-tRNA synthetase, C-terminal tRNA_edit PF04073.15 CBZ25630.1 - 6.2e-21 74.7 0.1 1.2e-20 73.9 0.1 1.5 1 0 0 1 1 1 1 Aminoacyl-tRNA editing domain tRNA-synt_2b PF00587.25 CBZ25630.1 - 2.3e-17 63.6 0.0 4e-17 62.7 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 CBZ25630.1 - 1.3e-11 44.4 0.0 4.3e-11 42.8 0.0 1.8 2 0 0 2 2 2 1 Anticodon binding domain SET PF00856.28 CBZ25631.1 - 1.6e-10 41.6 0.0 2.8e-10 40.8 0.0 1.4 1 0 0 1 1 1 1 SET domain Med26_M PF15694.5 CBZ25631.1 - 1.1 9.2 9.2 2.2 8.3 9.2 1.4 1 0 0 1 1 1 0 Mediator complex subunit 26 middle domain PIH1 PF08190.12 CBZ25632.1 - 5.1e-20 71.6 0.0 8.5e-08 31.8 0.0 3.4 2 1 1 3 3 3 3 PIH1 N-terminal domain PIH1_CS PF18201.1 CBZ25632.1 - 1.7e-09 38.0 0.0 6e-09 36.2 0.0 2.0 2 0 0 2 2 2 1 PIH1 CS-like domain PRC2_HTH_1 PF18118.1 CBZ25632.1 - 0.24 12.2 2.4 29 5.5 0.0 2.7 2 0 0 2 2 2 0 Polycomb repressive complex 2 tri-helical domain CPSF100_C PF13299.6 CBZ25632.1 - 6.7 6.9 7.8 20 5.3 0.2 2.6 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal Myb_DNA-binding PF00249.31 CBZ25633.1 - 0.026 14.7 0.0 0.043 14.0 0.0 1.4 1 0 0 1 1 1 0 Myb-like DNA-binding domain MCRS_N PF13325.6 CBZ25633.1 - 0.033 14.2 0.0 0.056 13.4 0.0 1.3 1 0 0 1 1 1 0 N-terminal region of micro-spherule protein Mito_carr PF00153.27 CBZ25634.1 - 7.1e-35 118.8 4.6 1.5e-13 50.5 0.0 3.5 3 1 0 3 3 3 3 Mitochondrial carrier protein Mito_carr PF00153.27 CBZ25635.1 - 2.1e-33 114.1 5.7 2.3e-12 46.6 0.1 3.5 3 1 0 3 3 3 3 Mitochondrial carrier protein Acetyltransf_1 PF00583.25 CBZ25636.1 - 7.1e-09 35.9 0.1 6.6e-06 26.3 0.0 2.6 2 0 0 2 2 2 2 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 CBZ25636.1 - 8.1e-06 26.2 0.0 0.00055 20.3 0.0 2.4 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 CBZ25636.1 - 0.00044 20.2 0.0 0.013 15.4 0.0 2.3 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Phytochelatin PF05023.14 CBZ25637.1 - 0.00013 21.3 0.0 3.9 6.6 0.0 3.7 3 0 0 3 3 3 3 Phytochelatin synthase CDP-OH_P_transf PF01066.21 CBZ25638.1 - 1.5e-20 73.7 0.2 1.5e-20 73.7 0.2 2.9 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase CTP_transf_like PF01467.26 CBZ25638.1 - 1.2e-15 57.9 0.0 2.2e-15 57.1 0.0 1.4 1 0 0 1 1 1 1 Cytidylyltransferase-like FAD_syn PF06574.12 CBZ25638.1 - 0.068 13.1 0.1 0.58 10.0 0.1 2.4 3 0 0 3 3 3 0 FAD synthetase zf-CCCH PF00642.24 CBZ25639.1 - 0.00097 19.0 9.9 0.26 11.2 0.1 2.7 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Torus PF16131.5 CBZ25639.1 - 0.0031 18.2 0.9 0.15 12.8 0.0 2.5 2 0 0 2 2 2 1 Torus domain zf_CCCH_4 PF18345.1 CBZ25639.1 - 0.0036 17.3 11.8 0.094 12.8 0.1 2.8 2 0 0 2 2 2 2 Zinc finger domain zf-CCCH_2 PF14608.6 CBZ25639.1 - 0.12 12.9 8.2 2.1 9.0 2.4 2.8 2 0 0 2 2 2 0 RNA-binding, Nab2-type zinc finger zf-CCCH_3 PF15663.5 CBZ25639.1 - 1.4 9.2 6.1 11 6.3 1.1 2.5 2 0 0 2 2 2 0 Zinc-finger containing family zf-CCCH PF00642.24 CBZ25640.1 - 0.00057 19.7 8.0 0.14 12.1 2.2 2.7 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 CBZ25640.1 - 0.0025 17.6 7.7 0.018 14.8 0.4 2.5 2 0 0 2 2 2 2 CCCH-type zinc finger Torus PF16131.5 CBZ25640.1 - 2 9.1 9.7 1.9 9.3 3.0 3.0 2 1 0 2 2 2 0 Torus domain zf_CCCH_4 PF18345.1 CBZ25640.1 - 5.6 7.2 14.9 1.3 9.1 3.2 2.9 3 0 0 3 3 3 0 Zinc finger domain HSP70 PF00012.20 CBZ25642.1 - 4.2e-107 358.8 1.0 1.6e-100 337.1 0.0 2.8 2 1 1 3 3 3 2 Hsp70 protein MreB_Mbl PF06723.13 CBZ25642.1 - 0.00058 18.8 0.5 0.0061 15.4 0.0 2.7 2 1 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.16 CBZ25642.1 - 0.013 15.2 0.0 0.029 14.1 0.0 1.5 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, C-terminal domain E1_dh PF00676.20 CBZ25643.1 - 6.5e-99 330.7 0.3 7.5e-99 330.4 0.3 1.0 1 0 0 1 1 1 1 Dehydrogenase E1 component DXP_synthase_N PF13292.6 CBZ25643.1 - 0.0021 17.3 1.6 0.0044 16.3 0.1 1.9 2 0 0 2 2 2 1 1-deoxy-D-xylulose-5-phosphate synthase ISG65-75 PF11727.8 CBZ25643.1 - 0.17 11.1 3.2 0.25 10.5 3.2 1.1 1 0 0 1 1 1 0 Invariant surface glycoprotein RRF PF01765.19 CBZ25643.1 - 1 9.3 6.9 1.6 8.7 6.9 1.2 1 0 0 1 1 1 0 Ribosome recycling factor HTH_32 PF13565.6 CBZ25644.1 - 0.09 13.4 3.6 0.11 13.2 0.8 2.3 2 0 0 2 2 2 0 Homeodomain-like domain Ribosomal_L34e PF01199.18 CBZ25645.1 - 8.4e-27 93.3 2.4 8.4e-27 93.3 2.4 2.2 2 1 0 2 2 2 1 Ribosomal protein L34e NARP1 PF12569.8 CBZ25645.1 - 0.51 9.2 9.4 0.56 9.0 9.4 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 PUF PF00806.19 CBZ25647.1 - 1.3e-45 150.6 0.4 1.3e-05 24.6 0.0 8.6 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat PMSR PF01625.21 CBZ25647.1 - 0.072 13.3 0.1 0.28 11.3 0.1 2.0 1 0 0 1 1 1 0 Peptide methionine sulfoxide reductase DnaJ PF00226.31 CBZ25648.1 - 3.2e-19 68.8 0.1 9.7e-19 67.3 0.1 1.9 1 0 0 1 1 1 1 DnaJ domain EF-hand_7 PF13499.6 CBZ25649.1 - 1e-11 45.1 1.1 2.5e-08 34.2 0.4 2.5 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 CBZ25649.1 - 6.1e-09 35.1 0.8 0.00016 21.3 0.0 3.6 3 0 0 3 3 3 2 EF-hand domain EF-hand_1 PF00036.32 CBZ25649.1 - 1.1e-07 30.8 1.5 0.0029 17.0 0.0 3.6 3 0 0 3 3 3 2 EF hand EF-hand_8 PF13833.6 CBZ25649.1 - 0.00068 19.4 4.9 0.15 12.0 0.1 3.4 3 1 1 4 4 4 2 EF-hand domain pair EF-hand_5 PF13202.6 CBZ25649.1 - 0.0019 17.6 2.4 0.017 14.6 0.1 3.1 3 0 0 3 3 3 1 EF hand DUF3648 PF12364.8 CBZ25650.1 - 1e-52 178.1 2.7 1e-52 178.1 2.7 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF3648) WD40 PF00400.32 CBZ25651.1 - 0.00016 22.4 2.3 0.13 13.2 0.1 3.4 4 0 0 4 4 4 2 WD domain, G-beta repeat NADH-G_4Fe-4S_3 PF10588.9 CBZ25653.1 - 1.5e-15 56.4 0.2 1.5e-15 56.4 0.2 2.2 2 0 0 2 2 2 1 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region Fer2_4 PF13510.6 CBZ25653.1 - 5.9e-12 45.5 1.5 5.9e-12 45.5 0.2 1.7 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Fer2 PF00111.27 CBZ25653.1 - 9.2e-08 31.9 0.2 2.3e-07 30.7 0.2 1.7 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer4_7 PF12838.7 CBZ25653.1 - 0.11 13.1 6.5 0.21 12.2 2.8 2.9 3 0 0 3 3 3 0 4Fe-4S dicluster domain Fer4_9 PF13187.6 CBZ25653.1 - 0.48 10.6 5.4 0.48 10.6 2.2 2.3 2 0 0 2 2 2 0 4Fe-4S dicluster domain DnaJ PF00226.31 CBZ25654.1 - 4e-13 49.3 0.0 9.9e-13 48.0 0.0 1.6 1 1 0 1 1 1 1 DnaJ domain zf-CSL PF05207.13 CBZ25654.1 - 2.7e-06 27.0 2.6 7.8e-06 25.5 2.6 1.8 1 1 0 1 1 1 1 CSL zinc finger E1-E2_ATPase PF00122.20 CBZ25656.1 - 5.3e-20 71.7 0.5 5.3e-19 68.4 0.8 2.2 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.26 CBZ25656.1 - 6.3e-07 29.9 0.0 1.3e-06 28.9 0.0 1.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 CBZ25656.1 - 0.0035 17.4 0.0 0.0067 16.5 0.0 1.4 1 0 0 1 1 1 1 Cation transport ATPase (P-type) YrvL PF14184.6 CBZ25656.1 - 0.083 13.0 7.7 0.2 11.8 7.7 1.6 1 0 0 1 1 1 0 Regulatory protein YrvL E1-E2_ATPase PF00122.20 CBZ25657.1 - 1.2e-45 155.3 2.6 5.6e-45 153.1 0.2 3.2 4 0 0 4 4 4 1 E1-E2 ATPase Hydrolase PF00702.26 CBZ25657.1 - 2.9e-17 63.7 0.0 7.7e-17 62.3 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 CBZ25657.1 - 2.8e-13 49.4 0.0 6.4e-13 48.2 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 CBZ25657.1 - 2.4e-05 24.2 0.1 0.00033 20.5 0.1 2.4 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 CBZ25657.1 - 0.0067 16.5 0.0 0.016 15.3 0.0 1.6 1 0 0 1 1 1 1 Cation transport ATPase (P-type) YrvL PF14184.6 CBZ25657.1 - 0.76 9.9 16.9 0.37 10.9 7.7 2.5 2 0 0 2 2 2 0 Regulatory protein YrvL Kinesin PF00225.23 CBZ25658.1 - 4.5e-47 160.6 0.1 9e-47 159.6 0.1 1.4 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 CBZ25658.1 - 1e-14 54.7 0.0 3.2e-14 53.1 0.0 1.8 1 0 0 1 1 1 1 Microtubule binding AAA_16 PF13191.6 CBZ25658.1 - 0.02 15.3 0.0 0.02 15.3 0.0 4.1 3 3 0 3 3 3 0 AAA ATPase domain AAA_22 PF13401.6 CBZ25658.1 - 0.031 14.6 0.6 0.19 12.0 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 CBZ25658.1 - 0.06 12.9 0.0 0.12 11.9 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA PF00004.29 CBZ25658.1 - 0.089 13.2 0.0 0.36 11.2 0.0 2.1 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Baculo_F PF12259.8 CBZ25658.1 - 0.18 10.3 1.2 0.27 9.7 1.2 1.2 1 0 0 1 1 1 0 Baculovirus F protein RNA_helicase PF00910.22 CBZ25658.1 - 0.18 12.2 0.0 0.41 11.0 0.0 1.6 1 0 0 1 1 1 0 RNA helicase FAM76 PF16046.5 CBZ25658.1 - 3.9 6.7 12.3 0.22 10.8 1.6 3.0 2 1 1 3 3 3 0 FAM76 protein UAA PF08449.11 CBZ25659.1 - 3.6e-49 167.6 8.7 7.6e-48 163.3 8.7 2.0 1 1 0 1 1 1 1 UAA transporter family Rep_1B PF17873.1 CBZ25659.1 - 0.023 14.5 0.0 0.053 13.4 0.0 1.6 1 0 0 1 1 1 0 Replicase polyprotein 1ab EamA PF00892.20 CBZ25659.1 - 7.8 6.7 18.9 0.7 10.1 6.7 3.8 2 2 2 4 4 4 0 EamA-like transporter family BTB PF00651.31 CBZ25660.1 - 0.0004 20.6 0.1 0.0017 18.6 0.0 2.0 2 0 0 2 2 2 1 BTB/POZ domain Vhr1 PF04001.13 CBZ25661.1 - 0.19 12.1 0.0 0.41 11.0 0.0 1.5 1 0 0 1 1 1 0 Transcription factor Vhr1 zf-C3HC4_3 PF13920.6 CBZ25662.1 - 3.1e-14 52.5 13.7 4.1e-14 52.2 13.7 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 CBZ25662.1 - 5.4e-06 26.2 14.0 7.8e-06 25.7 14.0 1.2 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 CBZ25662.1 - 0.00063 20.0 16.5 0.00094 19.5 16.5 1.3 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 CBZ25662.1 - 0.25 11.1 6.0 0.12 12.1 3.2 2.0 2 0 0 2 2 2 0 RING-like zinc finger IU_nuc_hydro PF01156.19 CBZ25663.1 - 5.7e-92 308.5 2.0 6.5e-92 308.4 2.0 1.0 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase Kinesin PF00225.23 CBZ25665.1 - 6.3e-62 209.4 0.1 1.2e-61 208.5 0.1 1.5 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 CBZ25665.1 - 3.2e-09 36.9 0.1 1.1e-08 35.2 0.0 1.9 2 1 0 2 2 2 1 Microtubule binding Miff PF05644.11 CBZ25665.1 - 0.062 12.9 2.8 0.095 12.3 0.0 2.5 3 0 0 3 3 3 0 Mitochondrial and peroxisomal fission factor Mff Noc2 PF03715.13 CBZ25666.1 - 2.7e-88 296.1 2.1 4.4e-88 295.4 2.1 1.3 1 0 0 1 1 1 1 Noc2p family DUF5401 PF17380.2 CBZ25666.1 - 0.014 13.5 5.1 0.027 12.5 5.1 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5401) YdjC PF04794.12 CBZ25666.1 - 0.067 13.2 1.1 0.31 11.0 0.1 2.4 2 0 0 2 2 2 0 YdjC-like protein PTPA PF03095.15 CBZ25666.1 - 0.079 12.4 2.3 6.6 6.1 0.1 2.6 3 0 0 3 3 3 0 Phosphotyrosyl phosphate activator (PTPA) protein Isy1 PF06246.12 CBZ25666.1 - 1.4 8.4 11.0 0.3 10.6 7.4 1.7 2 0 0 2 2 2 0 Isy1-like splicing family UPF0242 PF06785.11 CBZ25666.1 - 2.6 8.1 12.3 0.15 12.1 0.4 2.3 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Got1 PF04178.12 CBZ25667.1 - 7.8e-12 45.6 14.9 9.5e-12 45.3 14.9 1.1 1 0 0 1 1 1 1 Got1/Sft2-like family Rtf2 PF04641.12 CBZ25669.1 - 0.039 13.3 2.1 0.15 11.4 0.4 2.1 2 0 0 2 2 2 0 Rtf2 RING-finger DnaJ PF00226.31 CBZ25671.1 - 1.8e-14 53.6 0.2 1.1e-13 51.0 0.1 2.2 2 0 0 2 2 2 1 DnaJ domain TPR_2 PF07719.17 CBZ25671.1 - 0.15 12.2 13.4 19 5.7 0.0 6.4 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_12 PF13424.6 CBZ25671.1 - 4.9 7.5 23.4 1.1 9.6 6.0 4.7 4 1 1 5 5 5 0 Tetratricopeptide repeat GCS PF03074.16 CBZ25672.1 - 1.6e-140 468.6 0.0 2.1e-140 468.2 0.0 1.1 1 0 0 1 1 1 1 Glutamate-cysteine ligase Syntaxin-6_N PF09177.11 CBZ25674.1 - 0.072 13.7 5.8 0.19 12.3 2.9 2.6 2 1 0 2 2 2 0 Syntaxin 6, N-terminal Laminin_II PF06009.12 CBZ25674.1 - 0.09 12.8 0.4 0.09 12.8 0.4 2.3 2 0 0 2 2 2 0 Laminin Domain II Baculo_PEP_C PF04513.12 CBZ25674.1 - 0.15 12.1 2.0 0.26 11.3 0.4 2.1 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Spc7 PF08317.11 CBZ25674.1 - 0.21 10.4 17.1 1.1 8.0 11.5 2.1 2 0 0 2 2 2 0 Spc7 kinetochore protein Rx_N PF18052.1 CBZ25674.1 - 0.25 11.7 8.2 5.2 7.4 3.5 3.4 2 2 1 3 3 3 0 Rx N-terminal domain Fib_alpha PF08702.10 CBZ25674.1 - 3.3 7.9 11.2 3.2 7.9 5.0 2.7 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family Histone PF00125.24 CBZ25676.1 - 1.2e-10 41.9 1.3 1.5e-10 41.5 1.3 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 CBZ25676.1 - 0.0015 18.8 0.3 0.003 17.8 0.3 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone GMP_synt_C PF00958.22 CBZ25676.1 - 0.03 14.4 1.1 0.044 13.8 0.7 1.5 1 1 0 1 1 1 0 GMP synthase C terminal domain Histone PF00125.24 CBZ25677.1 - 1.2e-10 41.9 1.3 1.5e-10 41.5 1.3 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 CBZ25677.1 - 0.0015 18.8 0.3 0.003 17.8 0.3 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone GMP_synt_C PF00958.22 CBZ25677.1 - 0.03 14.4 1.1 0.044 13.8 0.7 1.5 1 1 0 1 1 1 0 GMP synthase C terminal domain Ribosomal_S5_C PF03719.15 CBZ25678.1 - 6.2e-25 86.5 0.0 9.9e-25 85.8 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain Ribosomal_S5 PF00333.20 CBZ25678.1 - 2.3e-21 75.5 0.3 4.7e-21 74.6 0.3 1.6 1 0 0 1 1 1 1 Ribosomal protein S5, N-terminal domain FoP_duplication PF13865.6 CBZ25678.1 - 0.18 12.3 3.8 0.35 11.4 3.8 1.4 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 SH3_9 PF14604.6 CBZ25679.1 - 1.7e-08 34.2 0.0 3.2e-08 33.3 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 CBZ25679.1 - 5.4e-08 32.3 0.0 1e-07 31.4 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 CBZ25679.1 - 0.00022 20.9 0.0 0.00049 19.7 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain Auts2 PF15336.6 CBZ25679.1 - 1.2 9.2 7.7 0.075 13.2 1.9 1.9 2 1 0 2 2 2 0 Autism susceptibility gene 2 protein Sporozoite_P67 PF05642.11 CBZ25679.1 - 2.4 6.1 4.2 3.3 5.7 4.2 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen DnaJ PF00226.31 CBZ25680.1 - 2.7e-20 72.2 0.3 1.2e-19 70.2 0.3 2.2 1 0 0 1 1 1 1 DnaJ domain DUF865 PF05906.11 CBZ25680.1 - 0.0043 16.8 0.8 0.0078 16.0 0.8 1.4 1 0 0 1 1 1 1 Herpesvirus-7 repeat of unknown function (DUF865) HydF_tetramer PF18133.1 CBZ25681.1 - 0.075 12.8 0.0 0.14 11.9 0.0 1.5 1 0 0 1 1 1 0 Hydrogen maturase F tetramerization domain DnaJ PF00226.31 CBZ25681.1 - 1 9.5 6.7 2.4 8.4 0.7 3.3 3 1 0 3 3 3 0 DnaJ domain Fibrillarin PF01269.17 CBZ25682.1 - 1.8e-99 331.4 0.0 2.1e-99 331.2 0.0 1.0 1 0 0 1 1 1 1 Fibrillarin GCD14 PF08704.10 CBZ25682.1 - 8.2e-07 29.0 0.0 1.1e-06 28.5 0.0 1.1 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit Methyltr_RsmB-F PF01189.17 CBZ25682.1 - 0.004 16.8 0.0 0.006 16.2 0.0 1.2 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F Lar_N PF09861.9 CBZ25682.1 - 0.14 11.3 0.0 0.23 10.6 0.0 1.3 1 0 0 1 1 1 0 Lactate racemase N-terminal domain FtsJ PF01728.19 CBZ25682.1 - 0.15 12.1 0.0 0.22 11.6 0.0 1.3 1 0 0 1 1 1 0 FtsJ-like methyltransferase Clathrin_lg_ch PF01086.17 CBZ25683.1 - 2.8e-07 30.9 3.5 3.5e-07 30.5 3.5 1.1 1 0 0 1 1 1 1 Clathrin light chain Na_trans_assoc PF06512.13 CBZ25683.1 - 0.027 14.7 0.6 0.032 14.5 0.6 1.0 1 0 0 1 1 1 0 Sodium ion transport-associated DUF2694 PF10904.8 CBZ25683.1 - 0.17 12.0 0.6 0.36 10.9 0.4 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF2694) NUDE_C PF04880.13 CBZ25683.1 - 0.28 11.6 6.5 0.31 11.5 5.5 1.7 1 1 1 2 2 2 0 NUDE protein, C-terminal conserved region Pet127 PF08634.10 CBZ25683.1 - 0.44 9.9 4.1 0.23 10.9 2.0 1.5 1 1 1 2 2 2 0 Mitochondrial protein Pet127 SNARE PF05739.19 CBZ25684.1 - 6.3e-10 38.9 1.3 1.1e-09 38.1 0.3 1.9 2 0 0 2 2 2 1 SNARE domain PspA_IM30 PF04012.12 CBZ25684.1 - 0.00029 20.5 1.7 0.00057 19.5 0.6 1.9 1 1 1 2 2 2 1 PspA/IM30 family Syntaxin_2 PF14523.6 CBZ25684.1 - 0.0028 18.0 5.4 0.081 13.3 0.2 2.4 2 0 0 2 2 2 2 Syntaxin-like protein Med9 PF07544.13 CBZ25684.1 - 0.0053 16.8 5.7 0.18 11.9 0.6 2.3 2 0 0 2 2 2 2 RNA polymerase II transcription mediator complex subunit 9 SPATA24 PF15175.6 CBZ25684.1 - 0.016 15.1 6.2 0.023 14.6 0.7 2.3 2 1 0 2 2 2 0 Spermatogenesis-associated protein 24 Sec2p PF06428.11 CBZ25684.1 - 0.036 14.0 0.3 0.036 14.0 0.3 2.5 2 1 0 2 2 2 0 GDP/GTP exchange factor Sec2p Vac_Fusion PF02346.16 CBZ25684.1 - 0.062 12.9 1.6 6.7 6.4 0.1 3.2 3 0 0 3 3 3 0 Chordopoxvirus multifunctional envelope protein A27 V_ATPase_I PF01496.19 CBZ25684.1 - 0.074 11.0 8.2 0.14 10.1 0.2 2.1 1 1 0 2 2 2 0 V-type ATPase 116kDa subunit family Cep57_MT_bd PF06657.13 CBZ25684.1 - 0.12 12.9 4.6 6.8 7.2 0.6 2.6 2 0 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 Spc7 PF08317.11 CBZ25684.1 - 0.28 10.0 13.2 0.32 9.8 3.6 2.1 1 1 1 2 2 2 0 Spc7 kinetochore protein UPF0242 PF06785.11 CBZ25684.1 - 0.33 11.1 10.6 0.82 9.8 10.6 1.6 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DER1 PF04511.15 CBZ25685.1 - 1.6e-32 113.0 8.0 1.8e-32 112.8 8.0 1.0 1 0 0 1 1 1 1 Der1-like family Pkinase PF00069.25 CBZ25686.1 - 3.6e-50 170.8 0.0 6.3e-50 170.0 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ25686.1 - 6.1e-25 88.0 0.0 5.2e-20 71.8 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase CAP_GLY PF01302.25 CBZ25686.1 - 3.5e-16 59.0 0.5 7.1e-16 58.0 0.5 1.5 1 0 0 1 1 1 1 CAP-Gly domain Kinase-like PF14531.6 CBZ25686.1 - 7.3e-05 22.2 0.1 0.03 13.6 0.0 2.2 2 0 0 2 2 2 2 Kinase-like APH PF01636.23 CBZ25686.1 - 0.76 9.6 3.9 0.54 10.1 0.2 2.2 2 0 0 2 2 2 0 Phosphotransferase enzyme family Pkinase PF00069.25 CBZ25687.1 - 2.2e-57 194.4 0.0 2.5e-57 194.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ25687.1 - 7.9e-34 117.1 0.0 9.3e-34 116.9 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CBZ25687.1 - 2.6e-05 23.2 0.0 3.6e-05 22.7 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase ABC1 PF03109.16 CBZ25687.1 - 0.01 16.0 0.0 0.026 14.7 0.0 1.7 2 0 0 2 2 2 1 ABC1 family Kinase-like PF14531.6 CBZ25687.1 - 0.19 11.0 0.0 0.28 10.5 0.0 1.1 1 0 0 1 1 1 0 Kinase-like Peptidase_M24 PF00557.24 CBZ25688.1 - 1e-22 80.9 1.1 1.4e-22 80.4 1.1 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 Pkinase PF00069.25 CBZ25690.1 - 9.3e-72 241.6 0.0 1.1e-71 241.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ25690.1 - 1.9e-32 112.5 0.0 3.8e-31 108.3 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 CBZ25690.1 - 0.044 13.7 0.0 0.073 13.0 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family MBF1 PF08523.10 CBZ25691.1 - 4.1e-12 46.4 4.5 4.1e-12 46.4 4.5 1.7 2 0 0 2 2 2 1 Multiprotein bridging factor 1 HTH_3 PF01381.22 CBZ25691.1 - 5.4e-11 42.4 0.2 1e-10 41.5 0.2 1.5 1 0 0 1 1 1 1 Helix-turn-helix HTH_31 PF13560.6 CBZ25691.1 - 0.0026 18.1 0.7 0.005 17.1 0.7 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_32 PF13565.6 CBZ25691.1 - 0.0041 17.7 1.9 0.005 17.4 0.4 1.8 2 0 0 2 2 2 1 Homeodomain-like domain HTH_19 PF12844.7 CBZ25691.1 - 0.012 15.6 0.1 0.023 14.7 0.1 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain MqsA_antitoxin PF15731.5 CBZ25691.1 - 0.065 13.3 0.4 0.1 12.7 0.4 1.4 1 1 0 1 1 1 0 Antitoxin component of bacterial toxin-antitoxin system, MqsA UPF0242 PF06785.11 CBZ25691.1 - 6.8 6.7 8.0 9.3 6.3 8.0 1.3 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Mito_carr PF00153.27 CBZ25692.1 - 3.2e-67 222.5 4.9 4.9e-24 84.1 0.1 3.0 2 1 1 3 3 3 3 Mitochondrial carrier protein Fuseless PF15993.5 CBZ25692.1 - 0.0046 16.2 0.1 0.0082 15.4 0.1 1.3 1 0 0 1 1 1 1 Fuseless Mito_carr PF00153.27 CBZ25693.1 - 3.2e-67 222.5 4.9 4.9e-24 84.1 0.1 3.0 2 1 1 3 3 3 3 Mitochondrial carrier protein Fuseless PF15993.5 CBZ25693.1 - 0.0046 16.2 0.1 0.0082 15.4 0.1 1.3 1 0 0 1 1 1 1 Fuseless polyprenyl_synt PF00348.17 CBZ25694.1 - 1.3e-51 175.1 0.0 1.8e-51 174.7 0.0 1.2 1 0 0 1 1 1 1 Polyprenyl synthetase CrtC PF07143.11 CBZ25694.1 - 3.7e-17 63.5 0.0 3.5e-16 60.3 0.0 2.1 1 1 0 1 1 1 1 CrtC N-terminal lipocalin domain Lipocalin_9 PF17186.4 CBZ25694.1 - 1e-09 38.7 0.0 2e-09 37.8 0.0 1.4 1 0 0 1 1 1 1 Lipocalin-like domain Complex1_LYR PF05347.15 CBZ25695.1 - 4.7e-08 33.0 0.4 7.4e-07 29.1 0.0 3.2 3 0 0 3 3 3 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 CBZ25695.1 - 0.0086 16.8 0.4 0.0086 16.8 0.4 3.1 3 1 0 3 3 3 1 Complex1_LYR-like GN3L_Grn1 PF08701.11 CBZ25696.1 - 4.8e-05 23.4 16.1 0.00011 22.2 16.1 1.6 1 0 0 1 1 1 1 GNL3L/Grn1 putative GTPase UVR PF02151.19 CBZ25697.1 - 6e-08 32.2 13.1 0.00015 21.4 1.1 2.8 2 0 0 2 2 2 2 UvrB/uvrC motif zf-Di19 PF05605.12 CBZ25697.1 - 0.02 15.2 6.4 0.02 15.2 6.4 2.9 2 1 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding Zn-C2H2_12 PF18112.1 CBZ25697.1 - 0.068 13.7 0.1 0.068 13.7 0.1 3.6 3 0 0 3 3 3 0 Autophagy receptor zinc finger-C2H2 domain zf-RAG1 PF10426.9 CBZ25697.1 - 1.2 9.3 8.4 1.4 9.1 0.7 3.0 2 0 0 2 2 2 0 Recombination-activating protein 1 zinc-finger domain zf-C2H2_4 PF13894.6 CBZ25697.1 - 1.3 10.1 17.2 0.29 12.1 0.7 4.8 4 0 0 4 4 4 0 C2H2-type zinc finger Kinesin PF00225.23 CBZ25698.1 - 1.6e-100 336.3 0.8 2.3e-100 335.8 0.0 1.6 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 CBZ25698.1 - 1.3e-44 151.7 0.0 4.5e-44 150.0 0.0 2.0 1 0 0 1 1 1 1 Microtubule binding VHS PF00790.19 CBZ25698.1 - 3.4e-05 23.7 0.2 0.00013 21.8 0.0 2.2 2 0 0 2 2 2 1 VHS domain Dor1 PF04124.12 CBZ25698.1 - 0.00055 18.7 2.2 0.0011 17.7 2.2 1.4 1 0 0 1 1 1 1 Dor1-like family CDC45 PF02724.14 CBZ25698.1 - 0.0062 14.9 2.7 0.01 14.2 2.7 1.3 1 0 0 1 1 1 1 CDC45-like protein Macoilin PF09726.9 CBZ25698.1 - 0.021 13.4 6.0 0.036 12.6 6.0 1.3 1 0 0 1 1 1 0 Macoilin family RAP1 PF07218.11 CBZ25698.1 - 0.077 11.3 0.0 0.15 10.4 0.0 1.4 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) DUF3837 PF12939.7 CBZ25698.1 - 0.12 12.7 1.8 19 5.7 1.3 3.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3837) Tup_N PF08581.10 CBZ25698.1 - 0.78 10.1 12.6 0.27 11.5 4.8 3.0 3 0 0 3 3 3 0 Tup N-terminal YlqD PF11068.8 CBZ25698.1 - 2.9 8.3 9.6 5.8 7.3 7.5 2.4 2 0 0 2 2 2 0 YlqD protein DUF4140 PF13600.6 CBZ25698.1 - 3.4 8.1 6.8 5.8 7.4 5.0 2.4 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) TPR_MLP1_2 PF07926.12 CBZ25698.1 - 3.8 7.6 22.1 2.2 8.4 11.8 3.1 2 1 1 3 3 3 0 TPR/MLP1/MLP2-like protein DUF5600 PF18150.1 CBZ25700.1 - 1.8e-17 63.8 0.0 3.4e-17 63.0 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF5600) Dynamin_N PF00350.23 CBZ25700.1 - 8e-15 55.3 0.0 5.7e-13 49.3 0.0 2.5 1 1 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.23 CBZ25700.1 - 4.6e-07 29.9 0.0 9.4e-07 28.9 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase EHD_N PF16880.5 CBZ25700.1 - 1.5e-05 24.7 0.5 6.1e-05 22.8 0.2 2.0 2 0 0 2 2 2 1 N-terminal EH-domain containing protein AAA_25 PF13481.6 CBZ25700.1 - 0.036 13.7 0.0 0.089 12.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 CBZ25700.1 - 0.085 12.8 0.0 7.7 6.4 0.0 2.9 3 0 0 3 3 3 0 RsgA GTPase AAA_22 PF13401.6 CBZ25700.1 - 0.094 13.0 0.0 1.5 9.1 0.0 2.7 3 0 0 3 3 3 0 AAA domain GET2 PF08690.10 CBZ25700.1 - 2.7 7.6 4.8 4.2 6.9 4.8 1.2 1 0 0 1 1 1 0 GET complex subunit GET2 U-box PF04564.15 CBZ25702.1 - 0.0022 18.1 0.0 0.0087 16.2 0.0 2.0 2 0 0 2 2 2 1 U-box domain zf-NOSIP PF15906.5 CBZ25702.1 - 0.0095 16.1 0.0 0.024 14.8 0.0 1.7 1 0 0 1 1 1 1 Zinc-finger of nitric oxide synthase-interacting protein DUF2937 PF11157.8 CBZ25702.1 - 0.058 13.1 0.1 0.1 12.3 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2937) zf_CCCH_4 PF18345.1 CBZ25702.1 - 0.99 9.6 8.1 0.86 9.8 1.4 2.5 2 0 0 2 2 2 0 Zinc finger domain zf-CCCH PF00642.24 CBZ25703.1 - 6.9e-05 22.6 6.9 0.0038 17.1 1.0 2.4 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) U-box PF04564.15 CBZ25703.1 - 0.0077 16.4 0.0 0.017 15.3 0.0 1.5 1 0 0 1 1 1 1 U-box domain zf-NOSIP PF15906.5 CBZ25703.1 - 0.024 14.7 0.0 0.053 13.7 0.0 1.6 1 0 0 1 1 1 0 Zinc-finger of nitric oxide synthase-interacting protein DUF5486 PF17588.2 CBZ25703.1 - 0.16 11.9 0.2 14 5.6 0.1 2.6 1 1 1 2 2 2 0 Family of unknown function (DUF5486) zf_CCCH_4 PF18345.1 CBZ25703.1 - 0.35 11.0 9.8 0.11 12.6 2.7 2.4 2 0 0 2 2 2 0 Zinc finger domain Menin PF05053.13 CBZ25703.1 - 1.9 6.7 7.9 2.6 6.3 7.9 1.1 1 0 0 1 1 1 0 Menin UPF0016 PF01169.19 CBZ25704.1 - 2e-43 146.6 19.5 2e-22 79.3 3.6 2.1 2 0 0 2 2 2 2 Uncharacterized protein family UPF0016 Ion_trans PF00520.31 CBZ25704.1 - 0.0036 16.6 0.2 0.0044 16.3 0.2 1.3 1 1 0 1 1 1 1 Ion transport protein MttA_Hcf106 PF02416.16 CBZ25704.1 - 0.99 8.8 3.8 7.2 6.0 0.2 2.4 2 0 0 2 2 2 0 mttA/Hcf106 family ABC_transp_aux PF09822.9 CBZ25705.1 - 5.6e-06 26.0 0.0 1e-05 25.2 0.0 1.4 1 0 0 1 1 1 1 ABC-type uncharacterized transport system DUF4350 PF14258.6 CBZ25705.1 - 0.0035 17.8 0.0 0.044 14.2 0.0 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF4350) WD40 PF00400.32 CBZ25706.1 - 2.3e-09 37.7 18.2 0.0086 16.9 0.0 6.0 7 0 0 7 7 7 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBZ25706.1 - 0.0019 18.5 0.1 21 5.5 0.0 5.3 3 1 2 6 6 6 1 Anaphase-promoting complex subunit 4 WD40 domain Coatomer_WDAD PF04053.14 CBZ25706.1 - 0.0065 15.6 0.0 0.017 14.2 0.0 1.6 1 0 0 1 1 1 1 Coatomer WD associated region Ge1_WD40 PF16529.5 CBZ25706.1 - 0.048 12.6 0.0 0.15 10.9 0.1 1.8 2 0 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Tachylectin PF14517.6 CBZ25706.1 - 0.23 11.0 0.8 0.89 9.0 0.1 2.3 3 0 0 3 3 3 0 Tachylectin DUF1143 PF06608.11 CBZ25707.1 - 0.00025 21.1 0.6 0.5 10.4 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF1143) Radical_SAM PF04055.21 CBZ25708.1 - 1.7e-10 41.5 0.3 2.7e-10 40.9 0.3 1.3 1 0 0 1 1 1 1 Radical SAM superfamily LIAS_N PF16881.5 CBZ25708.1 - 4.6e-10 39.9 0.0 1.2e-09 38.5 0.0 1.8 2 0 0 2 2 2 1 N-terminal domain of lipoyl synthase of Radical_SAM family Pkinase PF00069.25 CBZ25709.1 - 2.2e-27 96.1 0.2 3.6e-15 56.1 0.0 4.1 3 1 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ25709.1 - 1.8e-06 27.4 0.2 0.039 13.2 0.2 2.8 3 0 0 3 3 3 2 Protein tyrosine kinase RIO1 PF01163.22 CBZ25709.1 - 0.011 15.3 0.0 0.02 14.5 0.0 1.3 1 0 0 1 1 1 0 RIO1 family WD40 PF00400.32 CBZ25711.1 - 9.8e-09 35.7 0.1 0.0085 16.9 0.0 5.1 4 0 0 4 4 4 2 WD domain, G-beta repeat PDZ_2 PF13180.6 CBZ25711.1 - 0.00017 21.8 0.0 0.00055 20.2 0.0 1.9 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 CBZ25711.1 - 0.0048 16.7 0.4 0.013 15.4 0.4 1.7 1 0 0 1 1 1 1 PDZ domain PQQ_3 PF13570.6 CBZ25711.1 - 0.84 10.2 7.0 9.3 6.9 0.1 4.3 3 0 0 3 3 3 0 PQQ-like domain Ribosomal_S13_N PF08069.12 CBZ25712.1 - 4.4e-24 84.3 1.5 8.6e-24 83.4 1.5 1.5 1 0 0 1 1 1 1 Ribosomal S13/S15 N-terminal domain Ribosomal_S15 PF00312.22 CBZ25712.1 - 1.9e-13 50.4 1.1 3.2e-13 49.7 1.1 1.3 1 0 0 1 1 1 1 Ribosomal protein S15 Synaptobrevin PF00957.21 CBZ25713.1 - 1.4e-11 44.1 0.0 2.6e-11 43.1 0.0 1.5 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.6 CBZ25713.1 - 0.067 13.2 0.0 0.19 11.8 0.0 1.7 2 0 0 2 2 2 0 Regulated-SNARE-like domain UMP1 PF05348.11 CBZ25714.1 - 4.2e-05 23.8 0.0 5.3e-05 23.4 0.0 1.1 1 0 0 1 1 1 1 Proteasome maturation factor UMP1 TFIIS_C PF01096.18 CBZ25715.1 - 5.3e-19 67.8 2.3 5.3e-19 67.8 2.3 3.0 4 0 0 4 4 4 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.16 CBZ25715.1 - 0.00012 21.8 2.1 0.00033 20.5 0.3 2.2 2 0 0 2 2 2 1 RNA polymerases M/15 Kd subunit Baculo_LEF5_C PF11792.8 CBZ25715.1 - 0.0073 16.0 0.1 0.018 14.7 0.1 1.7 1 0 0 1 1 1 1 Baculoviridae late expression factor 5 C-terminal domain TF_Zn_Ribbon PF08271.12 CBZ25715.1 - 0.015 14.8 0.6 0.81 9.2 0.1 2.4 2 0 0 2 2 2 0 TFIIB zinc-binding zinc_ribbon_10 PF10058.9 CBZ25715.1 - 0.017 14.8 3.7 3.7 7.4 0.1 3.3 3 0 0 3 3 3 0 Predicted integral membrane zinc-ribbon metal-binding protein PhnA_Zn_Ribbon PF08274.12 CBZ25715.1 - 0.16 11.9 6.3 1.5 8.8 0.1 3.0 2 1 1 3 3 3 0 PhnA Zinc-Ribbon Zn_Tnp_IS1595 PF12760.7 CBZ25715.1 - 0.2 11.7 6.7 0.44 10.6 0.2 2.9 2 1 1 3 3 3 0 Transposase zinc-ribbon domain NAP PF00956.18 CBZ25717.1 - 2.2e-56 191.0 0.2 2.2e-56 191.0 0.2 1.5 2 0 0 2 2 2 1 Nucleosome assembly protein (NAP) DNA_pol_phi PF04931.13 CBZ25717.1 - 1.5 6.8 6.7 2.5 6.1 6.7 1.3 1 0 0 1 1 1 0 DNA polymerase phi PGA2 PF07543.12 CBZ25717.1 - 5.5 7.0 8.9 0.62 10.0 2.5 2.6 2 1 1 3 3 3 0 Protein trafficking PGA2 CCDC53 PF10152.9 CBZ25719.1 - 3.1e-43 147.9 0.0 3.9e-43 147.5 0.0 1.1 1 0 0 1 1 1 1 Subunit CCDC53 of WASH complex YebO PF13974.6 CBZ25719.1 - 0.062 13.4 0.1 0.1 12.7 0.1 1.3 1 0 0 1 1 1 0 YebO-like protein SPX PF03105.19 CBZ25719.1 - 0.13 12.1 1.5 0.17 11.7 1.5 1.1 1 0 0 1 1 1 0 SPX domain UPF0193 PF05250.11 CBZ25723.1 - 0.00014 21.7 3.1 0.00028 20.7 3.1 1.4 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0193) Lipoprotein_20 PF13942.6 CBZ25723.1 - 0.16 11.8 0.1 0.16 11.8 0.1 1.7 2 0 0 2 2 2 0 YfhG lipoprotein PilJ PF13675.6 CBZ25723.1 - 0.34 11.0 5.5 0.2 11.7 1.2 2.5 3 0 0 3 3 3 0 Type IV pili methyl-accepting chemotaxis transducer N-term RPAP1_N PF08621.10 CBZ25723.1 - 4.6 7.1 7.6 0.86 9.4 0.2 2.7 3 0 0 3 3 3 0 RPAP1-like, N-terminal ATP-synt_E PF05680.12 CBZ25724.1 - 9.7 6.6 6.4 2.1 8.8 1.0 2.5 2 0 0 2 2 2 0 ATP synthase E chain LRR_4 PF12799.7 CBZ25726.1 - 2.3e-05 24.6 0.1 0.025 15.0 0.0 3.4 4 0 0 4 4 4 2 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 CBZ25726.1 - 0.0013 18.3 0.0 0.0061 16.1 0.0 1.8 1 1 0 1 1 1 1 Leucine-rich repeat LRR_8 PF13855.6 CBZ25726.1 - 0.0065 16.2 0.2 1.4 8.7 0.0 2.4 2 0 0 2 2 2 2 Leucine rich repeat 5HT_transport_N PF03491.13 CBZ25726.1 - 2.1 8.6 6.8 0.11 12.7 0.4 2.3 3 0 0 3 3 3 0 Serotonin (5-HT) neurotransmitter transporter, N-terminus Peptidase_M24 PF00557.24 CBZ25727.1 - 2.2e-46 158.2 0.0 3.1e-46 157.7 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 zf-C6H2 PF15801.5 CBZ25727.1 - 2.6e-14 53.3 6.6 5.1e-14 52.3 6.6 1.5 1 0 0 1 1 1 1 zf-MYND-like zinc finger, mRNA-binding zf-MYND PF01753.18 CBZ25727.1 - 3.7e-05 23.7 3.6 7.8e-05 22.7 3.6 1.6 1 0 0 1 1 1 1 MYND finger CH_2 PF06294.11 CBZ25728.1 - 4.5e-17 62.0 0.0 8.7e-17 61.0 0.0 1.5 1 0 0 1 1 1 1 CH-like domain in sperm protein G-gamma PF00631.22 CBZ25729.1 - 0.023 14.7 0.2 0.073 13.1 0.1 1.9 2 0 0 2 2 2 0 GGL domain DUF996 PF06195.13 CBZ25729.1 - 0.15 12.3 5.5 0.3 11.4 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF996) DUF996 PF06195.13 CBZ25730.1 - 0.017 15.4 3.5 0.19 12.0 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF996) G-gamma PF00631.22 CBZ25730.1 - 0.022 14.8 0.1 0.053 13.5 0.1 1.6 1 0 0 1 1 1 0 GGL domain CitMHS PF03600.16 CBZ25730.1 - 0.034 13.4 1.7 0.39 9.9 0.1 2.4 2 0 0 2 2 2 0 Citrate transporter DUF2207 PF09972.9 CBZ25730.1 - 9.3 4.9 13.5 1.9e+02 0.5 0.0 3.0 2 1 0 2 2 2 0 Predicted membrane protein (DUF2207) TBCC PF07986.12 CBZ25731.1 - 2.8e-27 94.8 9.9 6.1e-10 38.9 0.0 3.4 3 0 0 3 3 3 3 Tubulin binding cofactor C CAP_C PF08603.11 CBZ25731.1 - 0.087 12.4 1.0 0.21 11.2 1.0 1.5 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) C terminal Pkinase PF00069.25 CBZ25732.1 - 3.1e-45 154.6 0.0 6e-35 120.9 0.0 3.2 3 0 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ25732.1 - 1.5e-14 53.9 0.0 1.2e-13 51.0 0.0 2.1 2 0 0 2 2 2 1 Protein tyrosine kinase DUF1216 PF06746.11 CBZ25733.1 - 0.15 12.1 0.0 0.39 10.7 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1216) DUF4118 PF13493.6 CBZ25734.1 - 0.068 13.0 3.0 0.12 12.2 3.0 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4118) CYTH PF01928.21 CBZ25735.1 - 4.5e-12 46.3 0.1 0.0002 21.3 0.0 3.7 4 0 0 4 4 4 2 CYTH domain Glycolytic PF00274.19 CBZ25735.1 - 0.012 14.4 0.8 0.056 12.2 0.1 2.0 2 0 0 2 2 2 0 Fructose-bisphosphate aldolase class-I Histone PF00125.24 CBZ25736.1 - 1.8e-37 128.6 3.1 2.3e-37 128.3 3.1 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 CBZ25736.1 - 2e-06 28.0 0.0 4.1e-06 27.0 0.0 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-T_C PF15511.6 CBZ25736.1 - 3.6e-05 23.8 0.1 3.6e-05 23.8 0.1 1.5 2 0 0 2 2 2 1 Centromere kinetochore component CENP-T histone fold Gene66 PF02053.15 CBZ25736.1 - 0.0041 16.8 0.3 0.0047 16.6 0.3 1.1 1 0 0 1 1 1 1 Gene 66 (IR5) protein TFIID-31kDa PF02291.15 CBZ25736.1 - 0.0053 16.8 0.0 0.0088 16.1 0.0 1.4 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit ORC4_C PF14629.6 CBZ25736.1 - 0.023 14.1 0.1 0.031 13.6 0.1 1.3 1 1 0 1 1 1 0 Origin recognition complex (ORC) subunit 4 C-terminus CENP-S PF15630.6 CBZ25736.1 - 0.082 13.3 0.1 0.16 12.4 0.1 1.4 1 0 0 1 1 1 0 CENP-S protein DUF4840 PF16128.5 CBZ25736.1 - 0.095 12.8 0.0 0.12 12.4 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4840) ANF_receptor PF01094.28 CBZ25737.1 - 1e-32 113.7 7.6 2.5e-26 92.6 2.1 3.2 2 1 0 2 2 2 2 Receptor family ligand binding region Peripla_BP_6 PF13458.6 CBZ25737.1 - 9.5e-06 25.5 4.2 0.00061 19.6 0.3 2.5 2 0 0 2 2 2 2 Periplasmic binding protein FliX PF10768.9 CBZ25738.1 - 0.058 13.9 2.5 2.5 8.6 0.5 3.7 3 0 0 3 3 3 0 Class II flagellar assembly regulator RNA_pol_A_bac PF01000.26 CBZ25739.1 - 1e-20 74.2 0.0 1.6e-20 73.5 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.24 CBZ25739.1 - 7.1e-14 51.0 0.0 1.1e-13 50.4 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Fer4_9 PF13187.6 CBZ25739.1 - 0.028 14.6 0.5 0.067 13.4 0.5 1.6 1 0 0 1 1 1 0 4Fe-4S dicluster domain Fer4_7 PF12838.7 CBZ25739.1 - 0.034 14.7 0.5 0.097 13.3 0.5 1.7 1 0 0 1 1 1 0 4Fe-4S dicluster domain Fer4_10 PF13237.6 CBZ25739.1 - 0.047 13.8 0.8 0.11 12.6 0.8 1.6 1 0 0 1 1 1 0 4Fe-4S dicluster domain Fer4_6 PF12837.7 CBZ25739.1 - 0.15 12.2 1.1 0.72 10.0 0.5 2.2 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4 PF00037.27 CBZ25739.1 - 0.17 11.8 1.1 1.1 9.2 0.3 2.3 2 0 0 2 2 2 0 4Fe-4S binding domain Utp11 PF03998.13 CBZ25740.1 - 2.2e-31 109.7 39.8 2.5e-31 109.5 23.8 2.1 1 1 1 2 2 2 1 Utp11 protein Kinesin PF00225.23 CBZ25741.1 - 2e-91 306.4 0.0 9.4e-91 304.2 0.0 2.2 3 0 0 3 3 3 1 Kinesin motor domain Microtub_bd PF16796.5 CBZ25741.1 - 5.2e-15 55.7 0.0 1.2e-09 38.3 0.0 3.0 2 0 0 2 2 2 2 Microtubule binding PHM7_ext PF12621.8 CBZ25741.1 - 0.1 12.8 0.3 0.4 10.9 0.3 2.0 1 0 0 1 1 1 0 Extracellular tail, of 10TM putative phosphate transporter AAA_22 PF13401.6 CBZ25741.1 - 0.24 11.7 2.2 4 7.7 0.1 3.2 2 0 0 2 2 2 0 AAA domain Kinesin PF00225.23 CBZ25742.1 - 4.3e-93 311.9 0.0 2e-92 309.7 0.0 2.2 3 0 0 3 3 3 1 Kinesin motor domain Microtub_bd PF16796.5 CBZ25742.1 - 6.7e-15 55.3 1.5 1.1e-09 38.4 0.0 3.4 4 0 0 4 4 4 2 Microtubule binding Kinesin_assoc PF16183.5 CBZ25742.1 - 0.0097 16.1 2.4 0.0097 16.1 2.4 2.7 2 1 1 3 3 3 1 Kinesin-associated Kinesin PF00225.23 CBZ25743.1 - 2.6e-94 315.9 1.0 7.7e-76 255.2 0.1 4.5 3 0 0 3 3 3 3 Kinesin motor domain Microtub_bd PF16796.5 CBZ25743.1 - 2.4e-15 56.8 0.1 9.7e-09 35.3 0.0 4.3 3 0 0 3 3 3 3 Microtubule binding Kinesin_assoc PF16183.5 CBZ25743.1 - 0.00039 20.6 3.5 0.00039 20.6 3.5 9.9 2 2 6 9 9 9 1 Kinesin-associated Ldh_1_C PF02866.18 CBZ25744.1 - 4.6e-35 121.0 0.0 6.8e-35 120.5 0.0 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Ldh_1_N PF00056.23 CBZ25744.1 - 1.1e-34 119.6 0.5 1.6e-34 119.0 0.5 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain 3Beta_HSD PF01073.19 CBZ25744.1 - 0.015 14.3 0.0 0.17 10.9 0.0 2.1 1 1 1 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family DUF1664 PF07889.12 CBZ25745.1 - 2.7e-06 27.4 11.0 0.014 15.4 0.9 3.4 2 2 1 3 3 3 2 Protein of unknown function (DUF1664) Spc7 PF08317.11 CBZ25745.1 - 6.3e-05 22.0 9.3 0.028 13.3 5.2 2.2 2 0 0 2 2 2 2 Spc7 kinetochore protein Baculo_PEP_C PF04513.12 CBZ25745.1 - 0.00042 20.4 4.7 2.7 8.0 0.6 3.5 1 1 3 4 4 4 2 Baculovirus polyhedron envelope protein, PEP, C terminus Alanine_zipper PF11839.8 CBZ25745.1 - 0.00059 20.2 1.3 0.00059 20.2 1.3 2.8 2 0 0 2 2 2 1 Alanine-zipper, major outer membrane lipoprotein Fez1 PF06818.15 CBZ25745.1 - 0.0017 18.9 12.6 0.019 15.4 5.6 2.3 1 1 1 2 2 2 1 Fez1 Helo_like_N PF17111.5 CBZ25745.1 - 0.0021 17.4 5.4 0.0063 15.9 3.8 2.5 1 1 0 2 2 2 1 Fungal N-terminal domain of STAND proteins Prefoldin_2 PF01920.20 CBZ25745.1 - 0.0068 16.3 4.8 0.88 9.6 0.0 3.5 3 2 0 3 3 3 1 Prefoldin subunit Laminin_II PF06009.12 CBZ25745.1 - 0.012 15.7 6.3 0.062 13.3 0.0 3.3 1 1 1 3 3 3 0 Laminin Domain II IFT57 PF10498.9 CBZ25745.1 - 0.012 14.6 4.5 0.034 13.1 0.9 2.2 2 0 0 2 2 2 0 Intra-flagellar transport protein 57 E2R135 PF11570.8 CBZ25745.1 - 0.017 15.5 0.6 0.017 15.5 0.6 2.3 1 1 1 2 2 2 0 Coiled-coil receptor-binding R-domain of colicin E2 Chlorosome_CsmC PF11098.8 CBZ25745.1 - 0.017 15.1 0.8 0.048 13.6 0.9 1.6 1 1 0 1 1 1 0 Chlorosome envelope protein C RmuC PF02646.16 CBZ25745.1 - 0.018 14.2 8.3 0.73 8.9 0.2 3.4 1 1 1 3 3 3 0 RmuC family DUF948 PF06103.11 CBZ25745.1 - 0.024 14.9 5.2 22 5.4 0.1 4.1 1 1 3 4 4 4 0 Bacterial protein of unknown function (DUF948) Bacillus_HBL PF05791.11 CBZ25745.1 - 0.026 14.3 1.5 0.36 10.6 0.2 2.7 2 1 1 3 3 3 0 Bacillus haemolytic enterotoxin (HBL) Syntaxin_2 PF14523.6 CBZ25745.1 - 0.027 14.8 3.6 5.2 7.5 0.0 3.4 1 1 1 2 2 2 0 Syntaxin-like protein Leu_zip PF15294.6 CBZ25745.1 - 0.028 13.9 8.0 2.6 7.5 4.3 2.8 1 1 3 4 4 4 0 Leucine zipper Tropomyosin_1 PF12718.7 CBZ25745.1 - 0.028 14.6 12.7 1.3 9.1 10.6 2.7 1 1 1 2 2 2 0 Tropomyosin like AKNA PF12443.8 CBZ25745.1 - 0.028 15.0 0.2 0.13 13.0 0.1 2.1 1 1 0 1 1 1 0 AT-hook-containing transcription factor Phage_GPO PF05929.11 CBZ25745.1 - 0.058 13.0 8.2 0.33 10.5 5.2 2.3 1 1 1 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase Fib_alpha PF08702.10 CBZ25745.1 - 0.11 12.7 6.2 0.77 9.9 1.3 3.3 1 1 4 5 5 5 0 Fibrinogen alpha/beta chain family BshC PF10079.9 CBZ25745.1 - 0.11 11.3 2.2 0.17 10.6 2.2 1.3 1 0 0 1 1 1 0 Bacillithiol biosynthesis BshC DUF4407 PF14362.6 CBZ25745.1 - 0.12 11.7 14.5 0.48 9.7 1.6 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) Pex19 PF04614.12 CBZ25745.1 - 0.12 12.1 6.3 0.67 9.7 5.1 2.0 1 1 1 2 2 2 0 Pex19 protein family Peptidase_M61 PF05299.12 CBZ25745.1 - 0.2 12.1 0.7 1.1 9.7 0.3 2.3 2 1 0 2 2 2 0 M61 glycyl aminopeptidase DUF892 PF05974.12 CBZ25745.1 - 0.22 11.5 7.6 1.5 8.8 2.9 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF892) Cob_adeno_trans PF01923.18 CBZ25745.1 - 0.27 11.4 5.9 1.7 8.7 1.7 2.8 1 1 1 3 3 3 0 Cobalamin adenosyltransferase CdvA PF18822.1 CBZ25745.1 - 0.33 10.8 10.9 4.1 7.2 1.2 4.2 3 2 2 5 5 5 0 CdvA-like coiled-coil domain ALIX_LYPXL_bnd PF13949.6 CBZ25745.1 - 0.4 9.9 14.3 0.05 12.9 4.7 2.9 1 1 1 3 3 3 0 ALIX V-shaped domain binding to HIV TPR_MLP1_2 PF07926.12 CBZ25745.1 - 0.41 10.7 15.8 0.87 9.7 0.5 3.6 1 1 3 4 4 4 0 TPR/MLP1/MLP2-like protein Atg14 PF10186.9 CBZ25745.1 - 0.43 9.6 7.2 0.35 9.9 5.1 1.7 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 Golgin_A5 PF09787.9 CBZ25745.1 - 0.44 10.0 16.0 1.1 8.6 10.3 2.4 1 1 0 2 2 2 0 Golgin subfamily A member 5 COG2 PF06148.11 CBZ25745.1 - 0.48 10.5 10.3 4.2 7.5 0.8 3.9 1 1 1 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF1043 PF06295.12 CBZ25745.1 - 0.81 9.7 8.7 0.59 10.2 3.3 3.1 2 1 0 3 3 3 0 Protein of unknown function (DUF1043) Syntaxin-6_N PF09177.11 CBZ25745.1 - 0.85 10.2 9.3 4.9 7.8 3.3 3.6 1 1 1 3 3 3 0 Syntaxin 6, N-terminal ISG65-75 PF11727.8 CBZ25745.1 - 1.1 8.5 7.4 0.61 9.3 3.1 2.2 1 1 1 2 2 2 0 Invariant surface glycoprotein zf-C4H2 PF10146.9 CBZ25745.1 - 1.6 9.0 10.9 2.4 8.4 7.2 2.2 1 1 0 2 2 2 0 Zinc finger-containing protein FlgN PF05130.12 CBZ25745.1 - 1.7 9.2 12.6 0.32 11.5 3.8 2.9 1 1 2 3 3 3 0 FlgN protein MAT1 PF06391.13 CBZ25745.1 - 1.8 8.3 8.3 0.37 10.6 4.9 1.5 2 0 0 2 2 1 0 CDK-activating kinase assembly factor MAT1 FadA PF09403.10 CBZ25745.1 - 1.9 9.1 6.2 1.5 9.3 0.8 3.1 2 1 1 3 3 3 0 Adhesion protein FadA Fibin PF15819.5 CBZ25745.1 - 2.8 7.7 9.7 1 9.1 2.5 2.8 1 1 0 2 2 2 0 Fin bud initiation factor homologue T7SS_ESX_EspC PF10824.8 CBZ25745.1 - 3.1 8.3 13.7 10 6.6 0.9 3.5 1 1 1 3 3 3 0 Excreted virulence factor EspC, type VII ESX diderm DLP_helical PF18709.1 CBZ25745.1 - 3.1 6.9 7.3 10 5.2 0.7 2.5 1 1 1 2 2 2 0 Dynamin-like helical domain DUF3347 PF11827.8 CBZ25745.1 - 3.5 7.8 5.2 2.9 8.0 1.6 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF3347) DUF4618 PF15397.6 CBZ25745.1 - 3.6 6.9 11.5 3.5 7.0 5.1 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF4618) DUF2730 PF10805.8 CBZ25745.1 - 4.8 7.3 6.7 3.3 7.9 0.1 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF2730) T3SS_needle_F PF09392.10 CBZ25745.1 - 5 7.4 8.3 6.4 7.1 0.3 4.3 4 2 3 7 7 5 0 Type III secretion needle MxiH, YscF, SsaG, EprI, PscF, EscF XhlA PF10779.9 CBZ25745.1 - 5.2 7.3 9.3 44 4.4 0.0 4.8 3 1 2 5 5 5 0 Haemolysin XhlA DUF4795 PF16043.5 CBZ25745.1 - 6.1 6.4 13.2 46 3.5 13.2 2.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4795) Phage_Mu_Gam PF07352.12 CBZ25745.1 - 6.6 6.6 7.2 20 5.1 0.2 2.9 2 1 0 3 3 3 0 Bacteriophage Mu Gam like protein CREPT PF16566.5 CBZ25745.1 - 7.2 6.8 10.3 7.4 6.7 3.9 3.0 2 2 1 3 3 3 0 Cell-cycle alteration and expression-elevated protein in tumour Methyltransf_11 PF08241.12 CBZ25746.1 - 4.8e-11 43.1 0.0 1.4e-10 41.7 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 CBZ25746.1 - 6.5e-10 39.7 0.0 1.2e-09 38.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CBZ25746.1 - 2.5e-09 37.7 0.0 5.3e-09 36.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 CBZ25746.1 - 9.5e-05 22.3 0.0 0.00019 21.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CBZ25746.1 - 0.00016 21.5 0.0 0.00041 20.2 0.0 1.7 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_8 PF05148.15 CBZ25746.1 - 0.0034 17.3 0.0 0.0065 16.4 0.0 1.4 1 0 0 1 1 1 1 Hypothetical methyltransferase Ubie_methyltran PF01209.18 CBZ25746.1 - 0.0053 16.1 0.0 0.0085 15.4 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family EAP30 PF04157.16 CBZ25747.1 - 7.6e-26 90.8 0.2 9.8e-26 90.5 0.2 1.1 1 0 0 1 1 1 1 EAP30/Vps36 family Vps36_ESCRT-II PF11605.8 CBZ25747.1 - 4e-25 87.8 0.0 6.7e-25 87.1 0.0 1.4 1 0 0 1 1 1 1 Vacuolar protein sorting protein 36 Vps36 Ribosomal_S25 PF03297.15 CBZ25747.1 - 0.0078 16.4 0.1 0.03 14.5 0.0 2.0 3 0 0 3 3 3 1 S25 ribosomal protein IRS PF02174.17 CBZ25747.1 - 0.065 13.1 0.0 0.14 12.1 0.0 1.5 1 0 0 1 1 1 0 PTB domain (IRS-1 type) Dscam_C PF12355.8 CBZ25747.1 - 0.11 13.5 0.3 0.23 12.4 0.3 1.5 1 0 0 1 1 1 0 Down syndrome cell adhesion molecule C terminal CAP_N PF01213.19 CBZ25747.1 - 0.43 10.0 2.3 0.2 11.1 0.2 1.4 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal Ribosomal_60s PF00428.19 CBZ25747.1 - 0.66 10.6 6.2 0.53 10.9 2.3 2.3 2 0 0 2 2 2 0 60s Acidic ribosomal protein Mem_trans PF03547.18 CBZ25749.1 - 4.5e-27 94.5 11.5 7.9e-26 90.4 11.5 2.4 1 1 0 1 1 1 1 Membrane transport protein MFS_MOT1 PF16983.5 CBZ25749.1 - 1.3 9.5 7.4 1.4 9.3 1.4 2.9 2 0 0 2 2 2 0 Molybdate transporter of MFS superfamily V-SNARE_C PF12352.8 CBZ25750.1 - 4.7e-08 33.2 2.0 4.7e-08 33.2 2.0 2.7 3 0 0 3 3 3 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.13 CBZ25750.1 - 3.2e-06 26.9 0.0 1.2e-05 25.2 0.0 1.9 2 0 0 2 2 2 1 Sec20 UPF0029 PF01205.19 CBZ25750.1 - 0.03 14.7 0.1 0.076 13.4 0.1 1.6 1 0 0 1 1 1 0 Uncharacterized protein family UPF0029 DUF3106 PF11304.8 CBZ25750.1 - 3.5 8.2 7.7 0.83 10.2 2.8 2.2 2 1 1 3 3 3 0 Protein of unknown function (DUF3106) DUF1691 PF07950.11 CBZ25751.1 - 0.18 12.6 2.5 0.42 11.4 0.5 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1691) SRP_TPR_like PF17004.5 CBZ25752.1 - 2.3e-11 43.7 2.3 2.3e-11 43.7 2.3 2.5 2 1 0 2 2 2 1 Putative TPR-like repeat ANAPC3 PF12895.7 CBZ25752.1 - 1.1e-06 28.8 16.8 3.5e-06 27.2 6.6 4.9 4 1 1 5 5 5 1 Anaphase-promoting complex, cyclosome, subunit 3 SRP72 PF08492.12 CBZ25752.1 - 1e-05 25.8 5.9 1e-05 25.8 5.9 3.3 3 1 1 4 4 4 1 SRP72 RNA-binding domain TPR_19 PF14559.6 CBZ25752.1 - 1.3e-05 25.6 36.9 0.0002 21.8 0.7 7.9 6 2 1 7 7 7 4 Tetratricopeptide repeat TPR_9 PF13371.6 CBZ25752.1 - 0.014 15.5 0.1 0.014 15.5 0.1 6.3 6 2 2 8 8 8 0 Tetratricopeptide repeat TPR_8 PF13181.6 CBZ25752.1 - 0.017 15.3 8.7 6.8 7.2 0.8 5.3 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_17 PF13431.6 CBZ25752.1 - 0.039 14.4 5.2 16 6.2 0.0 4.6 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_7 PF13176.6 CBZ25752.1 - 0.043 13.9 8.9 1.6 9.0 1.2 5.1 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_2 PF07719.17 CBZ25752.1 - 0.24 11.6 23.7 3.5 8.0 0.2 6.7 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_4 PF07721.14 CBZ25752.1 - 1.5 9.7 34.0 4.6 8.2 0.0 8.9 8 0 0 8 8 7 0 Tetratricopeptide repeat TPR_1 PF00515.28 CBZ25752.1 - 3.2 7.7 11.9 23 5.0 1.7 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.6 CBZ25752.1 - 4.8 8.3 47.4 2.1 9.4 3.2 9.4 7 3 3 10 10 9 0 Tetratricopeptide repeat ABC_tran PF00005.27 CBZ25753.1 - 5e-43 146.9 0.0 1.3e-20 74.3 0.0 3.0 3 0 0 3 3 2 2 ABC transporter ABC_tran_Xtn PF12848.7 CBZ25753.1 - 1.8e-22 79.2 6.3 4e-21 74.8 3.1 2.5 2 0 0 2 2 2 1 ABC transporter AAA_21 PF13304.6 CBZ25753.1 - 2.8e-21 76.6 0.0 1.8e-05 24.7 0.0 4.3 4 0 0 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 CBZ25753.1 - 1.1e-11 44.6 1.4 0.0024 17.3 0.0 4.8 4 1 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_33 PF13671.6 CBZ25753.1 - 3.1e-07 30.7 0.0 0.036 14.2 0.0 3.3 3 0 0 3 3 3 2 AAA domain AAA_28 PF13521.6 CBZ25753.1 - 4e-07 30.4 0.0 0.013 15.8 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_23 PF13476.6 CBZ25753.1 - 7.4e-07 29.9 7.5 0.031 14.8 0.0 3.7 4 0 0 4 4 3 2 AAA domain AAA PF00004.29 CBZ25753.1 - 1.5e-06 28.7 0.0 0.009 16.4 0.0 2.9 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 CBZ25753.1 - 1.8e-06 28.5 0.0 0.0088 16.4 0.0 2.5 2 0 0 2 2 2 2 AAA ATPase domain RNA_helicase PF00910.22 CBZ25753.1 - 2.8e-06 27.7 0.2 0.019 15.3 0.0 3.5 4 0 0 4 4 3 1 RNA helicase AAA_18 PF13238.6 CBZ25753.1 - 3.1e-06 27.8 0.0 0.037 14.6 0.0 2.9 3 0 0 3 3 2 2 AAA domain AAA_15 PF13175.6 CBZ25753.1 - 6.8e-06 26.0 0.3 0.33 10.6 0.0 3.6 4 0 0 4 4 4 2 AAA ATPase domain AAA_29 PF13555.6 CBZ25753.1 - 1.6e-05 24.5 0.1 0.22 11.3 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_5 PF07728.14 CBZ25753.1 - 4.5e-05 23.5 0.1 0.048 13.7 0.0 2.6 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 CBZ25753.1 - 5.9e-05 23.4 0.0 0.07 13.4 0.0 2.8 2 1 0 2 2 2 1 AAA domain TsaE PF02367.17 CBZ25753.1 - 6.9e-05 22.8 0.2 0.0053 16.8 0.0 3.0 2 1 1 3 3 3 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE NACHT PF05729.12 CBZ25753.1 - 0.00015 21.8 0.1 0.26 11.2 0.0 2.8 3 0 0 3 3 3 1 NACHT domain AAA_14 PF13173.6 CBZ25753.1 - 0.00015 21.8 0.0 2.1 8.4 0.0 3.6 4 0 0 4 4 3 2 AAA domain RsgA_GTPase PF03193.16 CBZ25753.1 - 0.00016 21.6 0.0 0.73 9.7 0.0 2.6 2 0 0 2 2 2 2 RsgA GTPase AAA_24 PF13479.6 CBZ25753.1 - 0.00025 20.8 0.0 0.1 12.3 0.0 2.9 3 0 0 3 3 3 1 AAA domain AAA_25 PF13481.6 CBZ25753.1 - 0.00034 20.2 0.0 1.8 8.1 0.0 3.2 3 0 0 3 3 3 2 AAA domain AAA_7 PF12775.7 CBZ25753.1 - 0.00065 19.3 0.0 0.12 11.9 0.0 2.5 2 0 0 2 2 2 1 P-loop containing dynein motor region Rad17 PF03215.15 CBZ25753.1 - 0.00085 19.3 0.1 0.36 10.7 0.0 2.5 2 0 0 2 2 2 1 Rad17 P-loop domain MMR_HSR1 PF01926.23 CBZ25753.1 - 0.00091 19.3 0.0 1.3 9.1 0.0 2.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_13 PF13166.6 CBZ25753.1 - 0.0017 17.1 0.0 2.5 6.6 0.0 3.5 3 0 0 3 3 3 1 AAA domain PduV-EutP PF10662.9 CBZ25753.1 - 0.0024 17.6 0.0 0.55 10.0 0.0 2.6 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation AAA_30 PF13604.6 CBZ25753.1 - 0.0033 17.2 0.4 1.5 8.5 0.0 3.2 3 1 0 3 3 2 1 AAA domain NB-ARC PF00931.22 CBZ25753.1 - 0.0034 16.6 0.0 1.3 8.1 0.0 2.4 2 0 0 2 2 2 1 NB-ARC domain dNK PF01712.19 CBZ25753.1 - 0.012 15.4 0.0 0.69 9.7 0.0 2.5 2 0 0 2 2 2 0 Deoxynucleoside kinase Mg_chelatase PF01078.21 CBZ25753.1 - 0.015 14.7 0.0 6.2 6.1 0.0 2.4 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 CBZ25753.1 - 0.021 14.5 0.0 2.6 7.7 0.0 2.5 2 0 0 2 2 2 0 IstB-like ATP binding protein ATPase_2 PF01637.18 CBZ25753.1 - 0.022 14.7 0.0 2.8 7.8 0.0 2.6 3 0 0 3 3 2 0 ATPase domain predominantly from Archaea RuvB_N PF05496.12 CBZ25753.1 - 0.023 14.5 0.1 0.3 10.8 0.0 2.2 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain Roc PF08477.13 CBZ25753.1 - 0.025 14.8 0.0 1.4 9.1 0.0 2.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase cobW PF02492.19 CBZ25753.1 - 0.026 14.1 0.1 2.4 7.7 0.0 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_27 PF13514.6 CBZ25753.1 - 0.028 14.0 0.0 14 5.2 0.0 3.0 3 0 0 3 3 3 0 AAA domain Zeta_toxin PF06414.12 CBZ25753.1 - 0.033 13.5 0.0 0.66 9.2 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin SRP54 PF00448.22 CBZ25753.1 - 0.035 13.7 0.1 0.75 9.4 0.0 2.5 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain NTPase_1 PF03266.15 CBZ25753.1 - 0.04 13.8 0.1 1.2 9.0 0.0 2.4 2 0 0 2 2 2 0 NTPase HSBP1 PF06825.12 CBZ25753.1 - 0.071 13.0 0.0 0.21 11.5 0.0 1.7 1 0 0 1 1 1 0 Heat shock factor binding protein 1 Cytidylate_kin PF02224.18 CBZ25753.1 - 0.081 12.6 0.1 4.6 6.9 0.0 2.8 3 0 0 3 3 3 0 Cytidylate kinase AAA_PrkA PF08298.11 CBZ25753.1 - 0.085 11.8 0.0 2.9 6.7 0.0 2.3 2 0 0 2 2 2 0 PrkA AAA domain MeaB PF03308.16 CBZ25753.1 - 0.087 11.8 0.5 1.8 7.5 0.0 2.5 3 0 0 3 3 3 0 Methylmalonyl Co-A mutase-associated GTPase MeaB ATP-synt_ab PF00006.25 CBZ25753.1 - 0.15 11.7 0.0 9.5 5.8 0.0 2.3 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain KapB PF08810.10 CBZ25753.1 - 0.16 12.2 1.6 0.23 11.6 0.0 2.1 3 0 0 3 3 1 0 Kinase associated protein B Vps53_N PF04100.12 CBZ25754.1 - 1.5e-64 218.3 10.9 2.1e-64 217.9 10.9 1.1 1 0 0 1 1 1 1 Vps53-like, N-terminal COG2 PF06148.11 CBZ25754.1 - 0.028 14.5 1.0 0.11 12.6 1.0 2.1 1 0 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 RACo_linker PF17650.1 CBZ25754.1 - 0.17 11.7 0.4 1.9 8.4 0.1 2.6 2 0 0 2 2 2 0 RACo linker region DUF1664 PF07889.12 CBZ25754.1 - 0.18 11.9 1.1 0.66 10.0 1.1 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) XhlA PF10779.9 CBZ25754.1 - 1.4 9.2 3.9 2.1 8.6 1.4 2.5 1 1 2 3 3 3 0 Haemolysin XhlA Atg8 PF02991.16 CBZ25755.1 - 9.5e-11 41.8 0.0 1.2e-10 41.5 0.0 1.1 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like ExbD PF02472.16 CBZ25755.1 - 0.025 14.8 0.0 0.027 14.6 0.0 1.1 1 0 0 1 1 1 0 Biopolymer transport protein ExbD/TolR YukD PF08817.10 CBZ25755.1 - 0.086 13.5 0.1 0.12 13.1 0.1 1.3 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukD EspB PF05802.11 CBZ25755.1 - 0.12 12.4 2.7 0.15 12.1 2.7 1.1 1 0 0 1 1 1 0 Enterobacterial EspB protein Atg8 PF02991.16 CBZ25756.1 - 9.5e-11 41.8 0.0 1.2e-10 41.5 0.0 1.1 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like ExbD PF02472.16 CBZ25756.1 - 0.025 14.8 0.0 0.027 14.6 0.0 1.1 1 0 0 1 1 1 0 Biopolymer transport protein ExbD/TolR YukD PF08817.10 CBZ25756.1 - 0.086 13.5 0.1 0.12 13.1 0.1 1.3 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukD EspB PF05802.11 CBZ25756.1 - 0.12 12.4 2.7 0.15 12.1 2.7 1.1 1 0 0 1 1 1 0 Enterobacterial EspB protein Atg8 PF02991.16 CBZ25757.1 - 9.5e-11 41.8 0.0 1.2e-10 41.5 0.0 1.1 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like ExbD PF02472.16 CBZ25757.1 - 0.025 14.8 0.0 0.027 14.6 0.0 1.1 1 0 0 1 1 1 0 Biopolymer transport protein ExbD/TolR YukD PF08817.10 CBZ25757.1 - 0.086 13.5 0.1 0.12 13.1 0.1 1.3 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukD EspB PF05802.11 CBZ25757.1 - 0.12 12.4 2.7 0.15 12.1 2.7 1.1 1 0 0 1 1 1 0 Enterobacterial EspB protein Atg8 PF02991.16 CBZ25758.1 - 1.1e-10 41.6 0.0 1.4e-10 41.3 0.0 1.1 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like ExbD PF02472.16 CBZ25758.1 - 0.027 14.6 0.0 0.03 14.5 0.0 1.1 1 0 0 1 1 1 0 Biopolymer transport protein ExbD/TolR YukD PF08817.10 CBZ25758.1 - 0.092 13.4 0.1 0.13 13.0 0.1 1.3 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukD EspB PF05802.11 CBZ25758.1 - 0.13 12.3 2.7 0.16 12.0 2.7 1.1 1 0 0 1 1 1 0 Enterobacterial EspB protein Atg8 PF02991.16 CBZ25759.1 - 9.6e-11 41.8 0.0 1.2e-10 41.5 0.0 1.1 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like ExbD PF02472.16 CBZ25759.1 - 0.025 14.8 0.0 0.027 14.6 0.0 1.1 1 0 0 1 1 1 0 Biopolymer transport protein ExbD/TolR YukD PF08817.10 CBZ25759.1 - 0.087 13.5 0.1 0.12 13.1 0.1 1.3 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukD EspB PF05802.11 CBZ25759.1 - 0.12 12.4 2.7 0.15 12.1 2.7 1.1 1 0 0 1 1 1 0 Enterobacterial EspB protein Atg8 PF02991.16 CBZ25761.1 - 1.6e-11 44.3 0.0 2.2e-11 43.9 0.0 1.2 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like APG5 PF04106.12 CBZ25761.1 - 0.11 12.1 0.0 0.11 12.0 0.0 1.1 1 0 0 1 1 1 0 Autophagy protein Apg5 Atg8 PF02991.16 CBZ25762.1 - 9.3e-11 41.9 0.0 1.2e-10 41.5 0.0 1.1 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like ExbD PF02472.16 CBZ25762.1 - 0.024 14.8 0.0 0.026 14.7 0.0 1.1 1 0 0 1 1 1 0 Biopolymer transport protein ExbD/TolR EspB PF05802.11 CBZ25762.1 - 0.11 12.5 2.4 0.13 12.2 2.4 1.1 1 0 0 1 1 1 0 Enterobacterial EspB protein BT1 PF03092.16 CBZ25763.1 - 1.5e-220 732.9 15.2 1.7e-220 732.7 15.2 1.0 1 0 0 1 1 1 1 BT1 family SHE3 PF17078.5 CBZ25764.1 - 0.24 11.1 0.0 2.1 8.0 0.0 2.0 2 0 0 2 2 2 0 SWI5-dependent HO expression protein 3 CAP_GLY PF01302.25 CBZ25765.1 - 7.9e-18 64.2 0.2 1.3e-17 63.5 0.2 1.3 1 0 0 1 1 1 1 CAP-Gly domain DUF1878 PF08963.10 CBZ25765.1 - 0.048 14.2 4.9 0.43 11.1 0.7 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1878) Salt_tol_Pase PF09506.10 CBZ25765.1 - 0.51 9.1 2.8 1.9 7.2 2.8 1.9 1 0 0 1 1 1 0 Glucosylglycerol-phosphate phosphatase (Salt_tol_Pase) SUZ PF12752.7 CBZ25765.1 - 0.71 10.7 6.9 6.2 7.7 0.0 3.5 2 1 0 2 2 2 0 SUZ domain Dynein_light PF01221.18 CBZ25767.1 - 5.5e-27 93.9 0.3 6.7e-27 93.6 0.3 1.1 1 0 0 1 1 1 1 Dynein light chain type 1 FKBP_C PF00254.28 CBZ25768.1 - 6.1e-12 45.7 0.0 9.8e-12 45.0 0.0 1.3 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase FKBP_N PF01346.18 CBZ25768.1 - 0.063 14.2 0.0 0.36 11.8 0.0 2.0 2 0 0 2 2 2 0 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase Cytochrom_B561 PF03188.16 CBZ25768.1 - 0.17 12.0 0.2 0.24 11.6 0.2 1.2 1 0 0 1 1 1 0 Eukaryotic cytochrome b561 FYVE PF01363.21 CBZ25769.1 - 1.4e-14 54.0 6.3 5e-14 52.2 6.3 1.9 1 1 0 1 1 1 1 FYVE zinc finger AMP-binding PF00501.28 CBZ25770.1 - 1.2e-87 294.3 3.4 1.5e-87 294.0 3.4 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 CBZ25770.1 - 4.7e-12 46.7 0.0 1.2e-11 45.5 0.0 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain AMP-binding PF00501.28 CBZ25771.1 - 1.7e-87 293.8 3.3 2e-87 293.5 3.3 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 CBZ25771.1 - 4.5e-12 46.8 0.0 1.1e-11 45.5 0.0 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain AMP-binding PF00501.28 CBZ25772.1 - 1.1e-79 268.0 0.2 1.4e-79 267.7 0.2 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 CBZ25772.1 - 1.4e-11 45.2 0.0 5.4e-11 43.3 0.0 2.1 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain WD40 PF00400.32 CBZ25773.1 - 9.1e-17 61.1 0.4 0.00014 22.6 0.3 7.5 8 0 0 8 8 8 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBZ25773.1 - 0.00095 19.4 0.0 3.6 7.9 0.0 3.6 3 0 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 CBZ25773.1 - 0.0061 15.3 0.1 0.51 8.9 0.0 2.2 2 0 0 2 2 2 2 Nucleoporin Nup120/160 eIF2A PF08662.11 CBZ25773.1 - 0.032 14.1 0.0 0.38 10.6 0.0 2.3 3 0 0 3 3 3 0 Eukaryotic translation initiation factor eIF2A EAGR_box PF16713.5 CBZ25773.1 - 0.24 11.1 0.3 0.4 10.4 0.3 1.3 1 0 0 1 1 1 0 Enriched in aromatic and glycine Residues box PseudoU_synth_1 PF01416.20 CBZ25774.1 - 4.5e-13 49.6 0.0 3.1e-11 43.7 0.0 2.6 2 0 0 2 2 2 1 tRNA pseudouridine synthase TP1 PF02079.16 CBZ25774.1 - 0.043 13.7 0.1 0.45 10.5 0.0 2.4 2 0 0 2 2 2 0 Nuclear transition protein 1 Cir_N PF10197.9 CBZ25775.1 - 0.0015 18.7 4.6 0.0015 18.7 4.6 3.6 3 2 1 4 4 4 1 N-terminal domain of CBF1 interacting co-repressor CIR tRNA_synthFbeta PF17759.1 CBZ25776.1 - 3e-39 134.7 0.0 4.5e-39 134.1 0.0 1.2 1 0 0 1 1 1 1 Phenylalanyl tRNA synthetase beta chain CLM domain PhetRS_B1 PF18262.1 CBZ25776.1 - 7e-30 103.1 0.1 2.2e-29 101.5 0.0 1.9 2 0 0 2 2 2 1 Phe-tRNA synthetase beta subunit B1 domain B5 PF03484.15 CBZ25776.1 - 5.8e-20 71.4 0.0 6.7e-15 55.1 0.0 2.6 2 0 0 2 2 2 2 tRNA synthetase B5 domain B3_4 PF03483.17 CBZ25776.1 - 1.9e-18 66.8 0.0 3.7e-18 65.8 0.0 1.5 1 0 0 1 1 1 1 B3/4 domain DUF3381 PF11861.8 CBZ25777.1 - 2 8.2 6.2 0.23 11.2 0.5 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3381) DUF2497 PF10691.9 CBZ25778.1 - 0.27 11.7 2.2 1.4 9.4 0.1 3.6 2 1 0 2 2 2 0 Protein of unknown function (DUF2497) DAGK_cat PF00781.24 CBZ25779.1 - 1.2e-09 37.8 0.0 1.7e-06 27.6 0.1 2.9 2 1 0 2 2 2 2 Diacylglycerol kinase catalytic domain Y2_Tnp PF04986.13 CBZ25781.1 - 0.069 13.2 0.0 0.091 12.8 0.0 1.1 1 0 0 1 1 1 0 Putative transposase Hum_adeno_E3A PF05393.11 CBZ25781.1 - 0.16 12.0 1.1 5.3 7.1 0.0 2.3 2 0 0 2 2 2 0 Human adenovirus early E3A glycoprotein Mto2_bdg PF12808.7 CBZ25782.1 - 0.026 14.8 1.6 0.14 12.5 1.6 2.3 1 0 0 1 1 1 0 Micro-tubular organiser Mto1 C-term Mto2-binding region betaPIX_CC PF16523.5 CBZ25782.1 - 0.29 11.0 3.3 0.35 10.7 1.5 2.1 1 1 0 1 1 1 0 betaPIX coiled coil DUF1515 PF07439.11 CBZ25782.1 - 0.4 10.7 3.3 1.8 8.7 3.1 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF1515) Mito_carr PF00153.27 CBZ25783.1 - 2.4e-51 171.6 5.1 1.3e-17 63.5 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein PCI PF01399.27 CBZ25784.1 - 1.9e-08 34.7 0.0 7.6e-08 32.8 0.0 2.1 2 0 0 2 2 2 1 PCI domain Ank_2 PF12796.7 CBZ25785.1 - 1.3e-26 93.0 22.6 3.2e-06 27.6 0.3 10.5 8 2 2 10 10 10 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CBZ25785.1 - 5.5e-12 46.0 13.7 0.0065 17.0 0.1 9.8 8 1 3 11 11 11 5 Ankyrin repeats (many copies) Ank PF00023.30 CBZ25785.1 - 5.7e-11 42.4 24.7 0.0028 18.0 0.3 11.7 13 0 0 13 13 13 4 Ankyrin repeat Ank_3 PF13606.6 CBZ25785.1 - 9.6e-11 40.9 29.5 0.19 12.4 0.1 14.5 17 0 0 17 17 17 3 Ankyrin repeat Ank_5 PF13857.6 CBZ25785.1 - 9e-09 35.4 14.2 0.33 11.3 0.4 8.8 8 1 1 9 9 9 4 Ankyrin repeats (many copies) DUF1501 PF07394.12 CBZ25786.1 - 0.094 11.8 1.8 0.18 10.8 1.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1501) FYVE PF01363.21 CBZ25786.1 - 0.61 10.3 4.8 0.69 10.1 1.9 2.6 3 0 0 3 3 3 0 FYVE zinc finger DNA_pol3_alpha PF07733.12 CBZ25788.1 - 0.01 15.4 0.1 0.01 15.4 0.1 1.9 2 0 0 2 2 2 0 Bacterial DNA polymerase III alpha NTPase domain Lzipper-MIP1 PF14389.6 CBZ25789.1 - 2.8 8.3 6.6 19 5.6 0.0 3.4 3 0 0 3 3 3 0 Leucine-zipper of ternary complex factor MIP1 CHCH PF06747.13 CBZ25791.1 - 1.4e-06 28.2 1.2 2.3e-06 27.6 1.2 1.4 1 0 0 1 1 1 1 CHCH domain Cmc1 PF08583.10 CBZ25791.1 - 0.0051 16.8 0.8 0.01 15.9 0.8 1.5 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like NDUF_B7 PF05676.13 CBZ25791.1 - 0.01 15.5 1.5 0.017 14.8 1.5 1.4 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) COX17 PF05051.13 CBZ25791.1 - 0.034 14.5 2.4 0.4 11.1 0.6 2.3 1 1 1 2 2 2 0 Cytochrome C oxidase copper chaperone (COX17) MTCP1 PF08991.10 CBZ25791.1 - 0.063 13.5 0.2 0.096 12.9 0.2 1.4 1 0 0 1 1 1 0 Mature-T-Cell Proliferation I type Actin PF00022.19 CBZ25792.1 - 1.1e-82 277.9 0.0 1.4e-82 277.5 0.0 1.1 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.13 CBZ25792.1 - 0.012 14.4 0.0 3.1 6.5 0.0 2.2 2 0 0 2 2 2 0 MreB/Mbl protein Fcf1 PF04900.12 CBZ25793.1 - 7.8e-31 106.4 2.6 1.5e-30 105.5 2.6 1.5 1 0 0 1 1 1 1 Fcf1 PIN_9 PF18477.1 CBZ25793.1 - 1.5e-13 51.1 0.0 2.9e-13 50.2 0.0 1.5 1 0 0 1 1 1 1 PIN like domain Thioredoxin PF00085.20 CBZ25794.1 - 0.012 15.6 0.1 0.023 14.7 0.1 1.6 1 1 0 1 1 1 0 Thioredoxin DUF5544 PF17698.1 CBZ25794.1 - 0.029 14.5 0.7 0.045 13.9 0.0 1.8 2 0 0 2 2 2 0 Family of unknown function (DUF5544) NMD3 PF04981.13 CBZ25794.1 - 0.04 13.4 0.3 0.12 11.8 0.2 1.6 1 1 1 2 2 2 0 NMD3 family TPR_10 PF13374.6 CBZ25794.1 - 0.044 13.7 0.1 0.15 12.0 0.1 1.9 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_4 PF07721.14 CBZ25794.1 - 0.044 14.4 1.1 0.085 13.5 0.0 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat Pex2_Pex12 PF04757.14 CBZ25797.1 - 1.9e-34 119.3 0.2 5.4e-34 117.8 0.2 1.6 1 1 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4_3 PF13920.6 CBZ25797.1 - 0.002 17.9 4.5 0.0037 17.1 4.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CBZ25797.1 - 0.037 14.4 2.0 0.068 13.5 2.0 1.4 1 0 0 1 1 1 0 Ring finger domain zf-C3HC4_2 PF13923.6 CBZ25797.1 - 0.1 12.4 2.6 0.2 11.6 2.6 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) NMD3 PF04981.13 CBZ25798.1 - 0.056 12.9 0.5 0.098 12.1 0.5 1.4 1 0 0 1 1 1 0 NMD3 family DZR PF12773.7 CBZ25798.1 - 0.095 12.7 0.2 0.17 11.9 0.2 1.4 1 0 0 1 1 1 0 Double zinc ribbon zf-Mss51 PF13824.6 CBZ25798.1 - 0.11 12.6 0.4 0.22 11.6 0.4 1.8 1 1 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 zf_C2H2_13 PF18508.1 CBZ25798.1 - 3.3 7.4 4.6 14 5.3 0.1 2.2 1 1 1 2 2 2 0 Zinc finger domain Surp PF01805.20 CBZ25799.1 - 3e-13 49.6 0.6 3e-13 49.6 0.6 2.0 2 0 0 2 2 2 1 Surp module Band_7 PF01145.25 CBZ25800.1 - 2.2e-28 99.5 0.2 9.3e-28 97.4 0.0 1.8 2 0 0 2 2 2 1 SPFH domain / Band 7 family Band_7_1 PF13421.6 CBZ25800.1 - 0.0091 15.7 0.3 0.022 14.5 0.0 1.8 2 0 0 2 2 2 1 SPFH domain-Band 7 family Band_7 PF01145.25 CBZ25801.1 - 2e-23 83.3 0.0 2.9e-23 82.8 0.0 1.2 1 0 0 1 1 1 1 SPFH domain / Band 7 family Pkinase PF00069.25 CBZ25802.1 - 0.00012 21.6 0.0 0.00076 18.9 0.0 2.2 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ25802.1 - 0.001 18.4 0.0 0.04 13.2 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Calsequestrin PF01216.17 CBZ25803.1 - 0.028 13.5 0.2 0.04 13.0 0.2 1.1 1 0 0 1 1 1 0 Calsequestrin SH3_4 PF06347.13 CBZ25803.1 - 0.072 12.9 0.1 0.29 11.0 0.1 2.0 1 0 0 1 1 1 0 Bacterial SH3 domain DUF4636 PF15468.6 CBZ25803.1 - 0.42 10.3 1.5 0.53 10.0 0.2 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4636) MBOAT PF03062.19 CBZ25805.1 - 7e-31 107.8 12.6 1.1e-30 107.2 12.6 1.3 1 0 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family MBOAT PF03062.19 CBZ25806.1 - 2.5e-30 106.0 13.5 5.9e-30 104.8 13.5 1.6 1 0 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family MBOAT PF03062.19 CBZ25807.1 - 8e-28 97.8 27.5 1.3e-24 87.3 25.9 3.9 2 1 1 3 3 3 1 MBOAT, membrane-bound O-acyltransferase family HCMV_UL124 PF17609.2 CBZ25807.1 - 0.32 11.2 0.1 0.32 11.2 0.1 2.4 2 0 0 2 2 2 0 Family of unknown function PAP2 PF01569.21 CBZ25808.1 - 3.5e-25 88.4 3.1 3.5e-25 88.4 3.1 2.3 2 1 0 2 2 2 1 PAP2 superfamily PAP2_3 PF14378.6 CBZ25808.1 - 0.03 14.0 13.6 0.015 15.0 6.3 3.1 2 1 0 2 2 2 0 PAP2 superfamily RDD PF06271.12 CBZ25808.1 - 1.9 8.7 8.1 0.23 11.7 2.8 2.0 2 1 0 2 2 2 0 RDD family PAP2 PF01569.21 CBZ25809.1 - 1.5e-25 89.5 3.1 2.2e-25 89.0 3.1 1.2 1 0 0 1 1 1 1 PAP2 superfamily PAP2_3 PF14378.6 CBZ25809.1 - 0.0011 18.7 3.1 0.0022 17.7 3.1 1.5 1 1 0 1 1 1 1 PAP2 superfamily DUF898 PF05987.13 CBZ25810.1 - 0.0062 15.6 0.1 0.0067 15.5 0.1 1.1 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF898) Cas1_AcylT PF07779.12 CBZ25810.1 - 0.0069 15.3 2.3 0.0084 15.1 2.3 1.1 1 0 0 1 1 1 1 10 TM Acyl Transferase domain found in Cas1p TrkH PF02386.16 CBZ25810.1 - 0.033 12.7 0.1 0.033 12.7 0.1 1.1 1 0 0 1 1 1 0 Cation transport protein DUF2207 PF09972.9 CBZ25810.1 - 0.15 10.8 1.4 0.21 10.3 1.4 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) BatA PF07584.11 CBZ25810.1 - 0.25 11.7 2.6 2.1 8.8 1.9 2.5 2 1 1 3 3 3 0 Aerotolerance regulator N-terminal Sigma_reg_N PF13800.6 CBZ25810.1 - 1.5 9.2 4.0 1.1 9.6 1.0 2.0 2 0 0 2 2 2 0 Sigma factor regulator N-terminal PDZ_6 PF17820.1 CBZ25812.1 - 0.00016 21.4 0.0 0.00057 19.7 0.0 2.0 1 0 0 1 1 1 1 PDZ domain DUF641 PF04859.12 CBZ25812.1 - 0.0036 17.6 0.0 0.0036 17.6 0.0 2.8 3 0 0 3 3 3 1 Plant protein of unknown function (DUF641) PDZ_2 PF13180.6 CBZ25812.1 - 0.014 15.7 0.0 0.071 13.4 0.0 2.2 2 0 0 2 2 2 0 PDZ domain SlyX PF04102.12 CBZ25812.1 - 0.089 13.4 7.5 0.82 10.3 0.2 3.8 3 0 0 3 3 3 0 SlyX PDZ PF00595.24 CBZ25812.1 - 0.11 12.9 0.0 0.31 11.4 0.0 1.8 1 0 0 1 1 1 0 PDZ domain BBP1_C PF15272.6 CBZ25812.1 - 0.15 11.9 1.9 0.33 10.7 0.1 2.1 2 0 0 2 2 2 0 Spindle pole body component BBP1, C-terminal Matrilin_ccoil PF10393.9 CBZ25812.1 - 0.43 10.5 3.9 0.55 10.1 0.3 2.4 2 0 0 2 2 2 0 Trimeric coiled-coil oligomerisation domain of matrilin DUF1690 PF07956.11 CBZ25812.1 - 3.2 8.2 7.3 0.99 9.8 1.6 2.7 3 0 0 3 3 3 0 Protein of Unknown function (DUF1690) Cation_efflux PF01545.21 CBZ25813.1 - 1e-31 110.2 8.0 7.3e-20 71.6 1.7 2.2 2 0 0 2 2 2 2 Cation efflux family TBP PF00352.21 CBZ25814.1 - 8.3e-42 141.0 0.1 1e-23 83.1 0.0 2.1 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) TPR_11 PF13414.6 CBZ25815.1 - 2e-09 36.9 0.0 0.012 15.3 0.0 4.3 4 0 0 4 4 4 2 TPR repeat TPR_1 PF00515.28 CBZ25815.1 - 2.5e-07 30.2 1.2 0.0013 18.5 0.0 4.1 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.17 CBZ25815.1 - 2.5e-07 30.3 6.6 0.0031 17.5 0.0 5.3 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_17 PF13431.6 CBZ25815.1 - 3.4e-07 30.2 0.4 0.13 12.7 0.0 3.9 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.6 CBZ25815.1 - 8e-06 25.7 3.5 0.0069 16.5 0.1 5.0 5 1 1 6 6 6 1 Tetratricopeptide repeat TPR_12 PF13424.6 CBZ25815.1 - 4.1e-05 23.8 0.4 0.0034 17.6 0.1 3.1 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 CBZ25815.1 - 0.0017 19.0 0.2 4.5 8.3 0.1 4.5 4 2 0 4 4 4 1 Tetratricopeptide repeat TPR_21 PF09976.9 CBZ25815.1 - 0.0019 17.9 0.2 0.0029 17.4 0.2 1.3 1 0 0 1 1 1 1 Tetratricopeptide repeat-like domain TPR_6 PF13174.6 CBZ25815.1 - 0.016 15.8 1.9 8.9 7.2 0.0 3.4 4 0 0 4 4 3 0 Tetratricopeptide repeat Sel1 PF08238.12 CBZ25815.1 - 0.041 14.6 2.0 2.9 8.7 0.1 3.2 3 0 0 3 3 3 0 Sel1 repeat TPR_10 PF13374.6 CBZ25815.1 - 0.051 13.5 0.0 0.66 9.9 0.1 2.9 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_16 PF13432.6 CBZ25815.1 - 0.12 13.0 0.1 5 7.9 0.0 3.1 2 2 1 3 3 3 0 Tetratricopeptide repeat PAP_assoc PF03828.19 CBZ25816.1 - 7.3e-15 54.9 0.2 1.8e-14 53.7 0.2 1.7 1 0 0 1 1 1 1 Cid1 family poly A polymerase DUF3090 PF11290.8 CBZ25816.1 - 0.077 12.8 0.6 0.37 10.6 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3090) Peptidase_C1 PF00112.23 CBZ25817.1 - 6e-68 229.2 1.5 8.3e-68 228.7 1.5 1.1 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.12 CBZ25817.1 - 7.5e-08 32.7 0.3 1.3e-07 32.0 0.3 1.4 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.15 CBZ25817.1 - 7.5e-06 25.0 1.0 0.0016 17.3 0.0 2.5 2 1 1 3 3 3 2 Peptidase C1-like family PIH1 PF08190.12 CBZ25818.1 - 5e-07 29.3 0.0 8.5e-07 28.6 0.0 1.3 1 0 0 1 1 1 1 PIH1 N-terminal domain PIH1_CS PF18201.1 CBZ25818.1 - 0.022 15.2 0.0 0.063 13.7 0.0 1.8 2 0 0 2 2 2 0 PIH1 CS-like domain Pkinase PF00069.25 CBZ25819.1 - 8e-66 222.1 0.0 9.6e-66 221.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ25819.1 - 1.8e-33 115.9 0.0 2.5e-33 115.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CBZ25819.1 - 1.8e-06 27.5 0.0 2.7e-06 26.9 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 CBZ25819.1 - 0.0017 18.3 0.9 0.0025 17.8 0.1 1.7 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 CBZ25819.1 - 0.0072 15.7 0.3 0.013 14.9 0.3 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 CBZ25819.1 - 0.033 13.1 0.1 0.047 12.6 0.1 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Oxidored-like PF09791.9 CBZ25820.1 - 5.6e-12 45.1 1.4 1.3e-11 43.9 1.4 1.6 1 0 0 1 1 1 1 Oxidoreductase-like protein, N-terminal NAD_binding_1 PF00175.21 CBZ25820.1 - 7.1e-11 42.7 0.0 1.3e-10 41.9 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_1 PF00667.20 CBZ25820.1 - 2.2e-06 27.4 0.0 0.0024 17.5 0.1 2.4 2 0 0 2 2 2 2 FAD binding domain DUF5522 PF17653.1 CBZ25820.1 - 0.28 11.2 2.9 0.56 10.2 2.9 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5522) COX6B PF02297.17 CBZ25821.1 - 0.014 15.7 1.8 0.031 14.5 1.8 1.7 1 1 0 1 1 1 0 Cytochrome oxidase c subunit VIb Pkinase PF00069.25 CBZ25822.1 - 1e-42 146.4 0.0 1.4e-29 103.3 0.0 3.1 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ25822.1 - 5.8e-17 61.8 0.0 1.1e-14 54.3 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.23 CBZ25822.1 - 0.029 14.3 0.1 0.061 13.2 0.1 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 CBZ25822.1 - 0.077 11.8 0.0 0.12 11.1 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase IF4E PF01652.18 CBZ25823.1 - 3.5e-39 134.1 0.0 5e-39 133.7 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E TPT PF03151.16 CBZ25825.1 - 2.1e-19 70.0 21.4 2.4e-19 69.8 21.4 1.0 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 CBZ25825.1 - 4.8e-05 23.6 30.2 6.7e-05 23.1 10.0 2.4 1 1 0 2 2 2 2 EamA-like transporter family TMEM252 PF15664.5 CBZ25825.1 - 0.13 12.0 0.0 0.27 10.9 0.0 1.5 1 0 0 1 1 1 0 Transmembrane protein 252 family Peptidase_S13 PF02113.15 CBZ25826.1 - 0.17 10.6 0.0 0.25 10.0 0.0 1.1 1 0 0 1 1 1 0 D-Ala-D-Ala carboxypeptidase 3 (S13) family FKBP_C PF00254.28 CBZ25827.1 - 2.4e-31 107.9 0.0 1.3e-30 105.5 0.0 2.1 2 0 0 2 2 2 1 FKBP-type peptidyl-prolyl cis-trans isomerase TPR_2 PF07719.17 CBZ25827.1 - 2.1e-11 43.0 0.5 0.00021 21.2 0.0 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.28 CBZ25827.1 - 1.6e-09 37.2 0.4 0.018 14.9 0.0 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_19 PF14559.6 CBZ25827.1 - 3.1e-07 30.8 5.2 3.7e-07 30.5 2.4 2.1 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.6 CBZ25827.1 - 9.7e-07 29.0 0.6 1.1 9.7 0.0 3.2 2 1 0 3 3 3 3 Tetratricopeptide repeat TPR_14 PF13428.6 CBZ25827.1 - 6.3e-05 23.5 3.9 0.0029 18.3 0.5 3.3 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.6 CBZ25827.1 - 0.00023 21.3 3.4 0.076 13.4 0.1 3.7 4 0 0 4 4 3 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 CBZ25827.1 - 0.00047 20.2 0.0 0.0028 17.7 0.0 2.2 1 1 1 2 2 2 1 Fis1 C-terminal tetratricopeptide repeat TPR_16 PF13432.6 CBZ25827.1 - 0.00047 20.7 1.5 0.35 11.6 0.1 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.6 CBZ25827.1 - 0.0014 18.7 0.1 13 6.3 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_10 PF13374.6 CBZ25827.1 - 0.0022 17.8 1.3 2.5 8.1 0.0 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat ANAPC3 PF12895.7 CBZ25827.1 - 0.0041 17.3 0.2 0.011 15.9 0.1 1.7 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.6 CBZ25827.1 - 0.006 16.5 0.6 0.77 9.9 0.1 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat FKBP_N_2 PF18023.1 CBZ25827.1 - 0.01 15.9 0.0 0.9 9.7 0.0 2.6 2 1 0 2 2 2 0 BDBT FKBP like N-terminal TPR_4 PF07721.14 CBZ25827.1 - 0.021 15.4 0.3 37 5.4 0.1 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.6 CBZ25827.1 - 0.21 12.3 1.4 0.65 10.8 0.0 2.5 3 0 0 3 3 3 0 Tetratricopeptide repeat Carn_acyltransf PF00755.20 CBZ25828.1 - 1.2e-150 503.0 0.0 1.7e-150 502.5 0.0 1.2 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase WD40 PF00400.32 CBZ25829.1 - 3.9e-11 43.3 2.6 0.00045 21.0 0.0 5.3 5 1 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBZ25829.1 - 2e-08 34.4 0.0 0.00021 21.5 0.0 3.7 3 1 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain RAB3GAP2_N PF14655.6 CBZ25829.1 - 0.03 13.6 0.0 0.054 12.7 0.0 1.5 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus PNPase_C PF12111.8 CBZ25829.1 - 3.2 7.3 5.2 2.2 7.8 2.9 1.9 2 0 0 2 2 2 0 Polyribonucleotide phosphorylase C terminal IMPDH PF00478.25 CBZ25830.1 - 2.5e-123 411.5 4.2 2.9e-123 411.3 4.2 1.0 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain CBS PF00571.28 CBZ25830.1 - 1.9e-14 53.9 0.2 9.3e-06 26.0 0.0 2.8 2 0 0 2 2 2 2 CBS domain FMN_dh PF01070.18 CBZ25830.1 - 1.7e-10 40.5 0.2 1.7e-10 40.5 0.2 1.6 2 0 0 2 2 2 1 FMN-dependent dehydrogenase NMO PF03060.15 CBZ25830.1 - 0.0001 21.8 2.7 0.22 10.9 2.3 2.5 2 1 0 2 2 2 2 Nitronate monooxygenase His_biosynth PF00977.21 CBZ25830.1 - 0.023 14.1 0.2 0.53 9.7 0.0 2.3 1 1 0 2 2 2 0 Histidine biosynthesis protein Formyl_trans_C PF02911.18 CBZ25830.1 - 0.15 12.4 0.0 4.7 7.5 0.0 2.5 2 0 0 2 2 2 0 Formyl transferase, C-terminal domain ELMO_CED12 PF04727.13 CBZ25831.1 - 2.8e-26 92.7 0.0 4.6e-26 92.0 0.0 1.3 1 0 0 1 1 1 1 ELMO/CED-12 family Peptidase_M41 PF01434.18 CBZ25833.1 - 5.9e-42 143.7 0.4 1e-41 142.9 0.4 1.4 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.29 CBZ25833.1 - 2.6e-40 137.9 0.0 3e-39 134.5 0.0 2.4 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 CBZ25833.1 - 0.00012 22.4 1.8 0.0072 16.6 0.1 3.1 2 1 1 3 3 3 1 AAA domain AAA_lid_3 PF17862.1 CBZ25833.1 - 0.00024 20.8 0.1 0.00098 18.9 0.1 2.0 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 CBZ25833.1 - 0.00076 19.9 6.8 0.013 15.9 0.3 3.9 2 2 0 2 2 2 1 AAA ATPase domain AAA_5 PF07728.14 CBZ25833.1 - 0.00093 19.2 0.0 0.0041 17.1 0.0 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 CBZ25833.1 - 0.0028 17.4 0.0 0.013 15.3 0.0 2.1 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain TIP49 PF06068.13 CBZ25833.1 - 0.0056 15.9 0.0 0.013 14.8 0.0 1.6 1 0 0 1 1 1 1 TIP49 P-loop domain Peptidase_M50B PF13398.6 CBZ25833.1 - 0.018 14.7 0.0 0.042 13.5 0.0 1.6 1 0 0 1 1 1 0 Peptidase M50B-like IstB_IS21 PF01695.17 CBZ25833.1 - 0.035 13.8 0.1 0.085 12.6 0.1 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_2 PF07724.14 CBZ25833.1 - 0.054 13.6 0.0 0.21 11.7 0.0 2.0 1 1 0 1 1 1 0 AAA domain (Cdc48 subfamily) DUF2075 PF09848.9 CBZ25833.1 - 0.071 12.3 0.0 0.13 11.5 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_14 PF13173.6 CBZ25833.1 - 0.1 12.6 0.0 0.21 11.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 CBZ25833.1 - 0.11 12.2 0.0 0.24 11.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 CBZ25833.1 - 0.11 12.4 0.0 0.38 10.7 0.0 1.9 1 0 0 1 1 1 0 NACHT domain ATPase PF06745.13 CBZ25833.1 - 0.18 11.1 0.1 0.55 9.5 0.1 1.8 1 0 0 1 1 1 0 KaiC SRP19 PF01922.17 CBZ25834.1 - 2.5e-21 76.4 0.1 3.6e-21 75.9 0.1 1.2 1 0 0 1 1 1 1 SRP19 protein RuvA_C PF07499.13 CBZ25834.1 - 0.13 12.7 0.0 0.89 10.1 0.0 2.2 2 1 1 3 3 3 0 RuvA, C-terminal domain Pkinase PF00069.25 CBZ25835.1 - 3.1e-20 72.7 0.0 3.7e-20 72.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ25835.1 - 3.3e-05 23.3 0.0 0.0001 21.7 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CBZ25835.1 - 0.011 14.5 0.0 0.017 14.0 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase BTB_2 PF02214.22 CBZ25836.1 - 2.8e-12 46.8 0.0 7.1e-12 45.5 0.0 1.7 1 0 0 1 1 1 1 BTB/POZ domain Atg8 PF02991.16 CBZ25837.1 - 1.8e-38 130.9 0.0 2.1e-38 130.7 0.0 1.0 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like APG12 PF04110.13 CBZ25837.1 - 1.1e-07 32.1 0.0 1.4e-07 31.8 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 Galactosyl_T PF01762.21 CBZ25840.1 - 0.00032 20.6 0.2 0.00095 19.0 0.0 1.8 2 0 0 2 2 2 1 Galactosyltransferase Lysyl_oxidase PF01186.17 CBZ25840.1 - 0.14 11.8 0.1 0.26 10.9 0.1 1.3 1 0 0 1 1 1 0 Lysyl oxidase CENP-T_C PF15511.6 CBZ25841.1 - 1e-06 28.8 0.1 1.5e-06 28.3 0.1 1.3 1 1 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CBFD_NFYB_HMF PF00808.23 CBZ25841.1 - 9.5e-05 22.6 0.8 0.00011 22.5 0.1 1.4 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TAF PF02969.17 CBZ25841.1 - 0.0002 21.5 0.2 0.00032 20.8 0.2 1.3 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) Bromo_TP PF07524.13 CBZ25841.1 - 0.00061 19.7 0.0 0.00077 19.4 0.0 1.2 1 0 0 1 1 1 1 Bromodomain associated Histone PF00125.24 CBZ25841.1 - 0.0034 17.7 2.2 0.0064 16.9 2.2 1.5 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID-31kDa PF02291.15 CBZ25841.1 - 0.011 15.8 0.0 0.014 15.4 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit PCP_red PF08369.10 CBZ25841.1 - 0.18 12.0 1.6 0.46 10.7 0.1 2.3 2 1 0 2 2 2 0 Proto-chlorophyllide reductase 57 kD subunit Amidohydro_1 PF01979.20 CBZ25843.1 - 7.2e-12 45.3 1.0 7.2e-11 42.0 1.0 2.4 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 CBZ25843.1 - 4.3e-09 36.4 0.1 0.006 16.1 0.0 3.0 3 0 0 3 3 3 2 Amidohydrolase family DHR-2 PF06920.13 CBZ25843.1 - 0.093 11.4 0.0 0.12 11.0 0.0 1.1 1 0 0 1 1 1 0 Dock homology region 2 PUF PF00806.19 CBZ25844.1 - 6e-33 110.7 11.4 7.7e-06 25.3 0.1 7.4 7 0 0 7 7 7 7 Pumilio-family RNA binding repeat CPL PF08144.11 CBZ25844.1 - 5e-06 26.9 0.4 3.8 7.9 0.0 4.2 1 1 3 4 4 4 3 CPL (NUC119) domain TFIIB_C_1 PF18542.1 CBZ25844.1 - 0.034 14.2 0.1 0.1 12.6 0.1 1.9 1 0 0 1 1 1 0 Transcription factor IIB C-terminal module 1 CYTH PF01928.21 CBZ25844.1 - 0.045 13.7 0.0 1.1 9.1 0.0 2.2 2 0 0 2 2 2 0 CYTH domain FGGY_C PF02782.16 CBZ25845.1 - 2.2e-36 125.4 0.1 4.1e-36 124.6 0.1 1.4 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.21 CBZ25845.1 - 7.2e-09 35.6 0.0 1.4e-08 34.6 0.0 1.5 1 1 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain DUF4702 PF15774.5 CBZ25845.1 - 0.03 13.3 0.0 0.046 12.7 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4702) SAP PF02037.27 CBZ25846.1 - 1.9e-12 46.6 0.3 3.3e-12 45.9 0.3 1.4 1 0 0 1 1 1 1 SAP domain TPR_1 PF00515.28 CBZ25847.1 - 1.9e-38 128.7 15.9 5.4e-07 29.2 0.6 6.2 6 0 0 6 6 6 6 Tetratricopeptide repeat TPR_2 PF07719.17 CBZ25847.1 - 6.6e-33 110.2 11.1 2.6e-07 30.2 0.0 6.3 6 1 0 6 6 6 5 Tetratricopeptide repeat TPR_8 PF13181.6 CBZ25847.1 - 5.4e-23 79.2 8.6 0.00019 21.4 0.1 6.2 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_11 PF13414.6 CBZ25847.1 - 1.6e-20 72.5 10.0 0.0011 18.6 0.1 6.0 4 2 2 6 6 6 5 TPR repeat TPR_7 PF13176.6 CBZ25847.1 - 9e-17 59.8 0.6 0.00052 19.9 0.0 5.4 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_12 PF13424.6 CBZ25847.1 - 4.6e-15 55.7 7.7 0.00042 20.6 0.1 4.3 2 2 2 4 4 4 4 Tetratricopeptide repeat TPR_16 PF13432.6 CBZ25847.1 - 5.7e-13 49.3 4.4 0.011 16.4 0.2 4.3 3 1 0 4 4 4 4 Tetratricopeptide repeat TPR_14 PF13428.6 CBZ25847.1 - 2.1e-11 43.6 2.3 0.019 15.8 0.0 5.2 2 2 4 6 6 6 3 Tetratricopeptide repeat TPR_17 PF13431.6 CBZ25847.1 - 1.7e-10 40.5 5.6 0.019 15.3 0.1 6.1 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_9 PF13371.6 CBZ25847.1 - 8.3e-10 38.7 0.3 0.00084 19.4 0.1 2.9 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_6 PF13174.6 CBZ25847.1 - 1.1e-09 38.3 7.6 0.0035 17.9 0.1 5.1 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_19 PF14559.6 CBZ25847.1 - 5e-09 36.5 7.1 0.025 15.1 0.1 4.6 4 1 1 5 5 5 3 Tetratricopeptide repeat SHNi-TPR PF10516.9 CBZ25847.1 - 1.6e-08 33.8 4.4 0.012 15.1 0.0 4.6 5 0 0 5 5 5 3 SHNi-TPR MIT PF04212.18 CBZ25847.1 - 3.1e-08 33.6 8.9 0.036 14.2 0.0 4.3 4 0 0 4 4 4 3 MIT (microtubule interacting and transport) domain TPR_10 PF13374.6 CBZ25847.1 - 6.6e-06 25.8 8.0 1.8 8.5 0.3 4.8 5 0 0 5 5 5 2 Tetratricopeptide repeat ANAPC3 PF12895.7 CBZ25847.1 - 1.8e-05 24.9 2.8 0.097 12.9 0.3 3.5 2 1 1 4 4 3 3 Anaphase-promoting complex, cyclosome, subunit 3 SPO22 PF08631.10 CBZ25847.1 - 0.002 17.7 5.8 0.027 14.0 0.3 3.1 4 0 0 4 4 4 1 Meiosis protein SPO22/ZIP4 like TPR_3 PF07720.12 CBZ25847.1 - 0.0034 17.3 6.2 0.063 13.3 0.1 3.8 3 0 0 3 3 3 1 Tetratricopeptide repeat DUF3856 PF12968.7 CBZ25847.1 - 0.0038 17.3 2.0 2 8.5 0.1 3.1 2 2 0 2 2 2 2 Domain of Unknown Function (DUF3856) Fis1_TPR_C PF14853.6 CBZ25847.1 - 0.015 15.4 2.9 0.4 10.8 0.0 4.1 4 1 1 5 5 5 0 Fis1 C-terminal tetratricopeptide repeat BTAD PF03704.17 CBZ25847.1 - 0.099 13.1 0.6 25 5.3 0.0 3.4 2 2 1 3 3 3 0 Bacterial transcriptional activator domain Sel1 PF08238.12 CBZ25847.1 - 1.2 9.9 10.0 15 6.5 0.0 4.3 4 1 1 5 5 4 0 Sel1 repeat LCM PF04072.14 CBZ25848.1 - 2e-23 83.3 0.0 7.9e-23 81.4 0.0 1.8 1 1 0 1 1 1 1 Leucine carboxyl methyltransferase SPO22 PF08631.10 CBZ25849.1 - 0.11 12.0 0.5 18 4.7 0.0 3.2 3 0 0 3 3 3 0 Meiosis protein SPO22/ZIP4 like IMS PF00817.20 CBZ25850.1 - 1.5e-34 119.1 0.1 3.1e-34 118.2 0.1 1.5 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.8 CBZ25850.1 - 0.0011 19.6 0.0 0.0028 18.3 0.0 1.7 1 1 0 1 1 1 1 impB/mucB/samB family C-terminal domain Pox_MCEL PF03291.16 CBZ25852.1 - 1.5e-31 109.7 0.0 1.1e-30 107.0 0.0 1.9 1 1 0 1 1 1 1 mRNA capping enzyme NNMT_PNMT_TEMT PF01234.17 CBZ25852.1 - 0.0097 15.1 0.1 0.19 10.9 0.1 2.1 2 0 0 2 2 2 1 NNMT/PNMT/TEMT family Methyltransf_23 PF13489.6 CBZ25852.1 - 0.11 12.3 0.0 0.47 10.3 0.0 1.9 1 1 0 1 1 1 0 Methyltransferase domain PUB PF09409.10 CBZ25853.1 - 9.5e-17 60.7 0.0 1.9e-16 59.8 0.0 1.5 1 0 0 1 1 1 1 PUB domain Atg14 PF10186.9 CBZ25853.1 - 5.4 6.0 10.8 7.4 5.6 10.8 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 His_Phos_1 PF00300.22 CBZ25855.1 - 1.4e-27 96.6 0.0 5.7e-27 94.7 0.0 2.0 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) GTP_EFTU PF00009.27 CBZ25858.1 - 5.7e-65 218.5 0.4 9.2e-65 217.8 0.4 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 CBZ25858.1 - 7.1e-29 100.0 0.0 2e-28 98.6 0.0 1.8 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_C PF00679.24 CBZ25858.1 - 7.4e-20 70.8 0.0 3.3e-19 68.7 0.0 2.1 2 0 0 2 2 2 1 Elongation factor G C-terminus EFG_II PF14492.6 CBZ25858.1 - 5.6e-14 52.0 0.0 3.1e-13 49.6 0.0 2.2 2 0 0 2 2 2 1 Elongation Factor G, domain II GTP_EFTU_D2 PF03144.25 CBZ25858.1 - 5.7e-14 52.3 0.1 1.6e-13 50.8 0.1 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 CBZ25858.1 - 0.0019 18.3 0.1 0.0051 16.9 0.1 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase Peptidase_S24 PF00717.23 CBZ25859.1 - 9e-07 28.8 0.0 1.4e-06 28.2 0.0 1.3 1 0 0 1 1 1 1 Peptidase S24-like Peptidase_S26 PF10502.9 CBZ25859.1 - 0.0043 16.8 0.0 0.007 16.2 0.0 1.4 1 0 0 1 1 1 1 Signal peptidase, peptidase S26 DUF551 PF04448.12 CBZ25859.1 - 0.042 14.8 0.7 0.23 12.4 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF551) SET PF00856.28 CBZ25860.1 - 1.4e-09 38.6 0.1 5.4e-08 33.4 0.1 2.3 1 1 0 1 1 1 1 SET domain RimK PF08443.11 CBZ25860.1 - 0.00095 18.8 0.0 0.0014 18.2 0.0 1.2 1 0 0 1 1 1 1 RimK-like ATP-grasp domain Glycos_transf_2 PF00535.26 CBZ25861.1 - 6.6e-33 113.9 0.0 9e-33 113.5 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 CBZ25861.1 - 0.0002 21.3 0.0 0.00026 21.0 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 NTP_transf_3 PF12804.7 CBZ25861.1 - 0.00098 19.5 0.0 0.0013 19.1 0.0 1.1 1 0 0 1 1 1 1 MobA-like NTP transferase domain Glyco_transf_21 PF13506.6 CBZ25861.1 - 0.18 11.3 0.0 0.28 10.6 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferase family 21 DUF2606 PF10794.9 CBZ25861.1 - 0.18 11.6 0.0 0.3 10.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2606) FKBP_C PF00254.28 CBZ25862.1 - 8e-27 93.4 0.0 9.4e-27 93.2 0.0 1.0 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase DUF4164 PF13747.6 CBZ25863.1 - 9.5e-05 22.6 7.1 9.5e-05 22.6 7.1 2.9 2 1 1 3 3 3 1 Domain of unknown function (DUF4164) ADIP PF11559.8 CBZ25863.1 - 0.00014 22.0 14.2 0.00014 22.0 14.2 1.9 2 0 0 2 2 2 1 Afadin- and alpha -actinin-Binding AIP3 PF03915.13 CBZ25863.1 - 0.0003 20.0 4.4 0.00039 19.6 4.4 1.1 1 0 0 1 1 1 1 Actin interacting protein 3 KASH_CCD PF14662.6 CBZ25863.1 - 0.0017 18.2 19.6 0.0017 18.2 19.6 1.6 2 0 0 2 2 2 1 Coiled-coil region of CCDC155 or KASH GAS PF13851.6 CBZ25863.1 - 0.047 13.0 17.4 0.34 10.2 15.5 2.3 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding Golgin_A5 PF09787.9 CBZ25863.1 - 0.094 12.2 15.6 0.06 12.8 12.4 1.8 2 0 0 2 2 2 0 Golgin subfamily A member 5 HAP1_N PF04849.13 CBZ25863.1 - 0.15 11.2 16.9 0.21 10.8 14.6 1.9 2 0 0 2 2 2 0 HAP1 N-terminal conserved region V_ATPase_I PF01496.19 CBZ25863.1 - 0.17 9.8 2.9 0.16 9.9 2.9 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Atg14 PF10186.9 CBZ25863.1 - 0.38 9.8 19.4 0.71 8.9 14.7 2.6 2 1 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 YabA PF06156.13 CBZ25863.1 - 0.39 11.4 13.2 8.5 7.1 5.8 2.9 2 1 1 3 3 3 0 Initiation control protein YabA CENP-F_leu_zip PF10473.9 CBZ25863.1 - 0.6 10.1 22.1 1.6 8.7 19.2 2.5 2 1 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 AKNA PF12443.8 CBZ25863.1 - 0.61 10.8 8.0 0.78 10.4 3.3 2.7 2 1 0 2 2 2 0 AT-hook-containing transcription factor FapA PF03961.13 CBZ25863.1 - 0.67 8.5 7.7 1.1 7.8 6.2 1.8 2 0 0 2 2 2 0 Flagellar Assembly Protein A HIP1_clath_bdg PF16515.5 CBZ25863.1 - 0.86 10.2 19.6 7.6 7.2 0.1 2.8 2 1 0 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 DUF1664 PF07889.12 CBZ25863.1 - 1.2 9.2 4.8 1.7 8.7 3.7 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) DivIC PF04977.15 CBZ25863.1 - 1.2 8.9 20.2 5.7 6.8 0.2 3.7 2 1 2 4 4 4 0 Septum formation initiator DUF4446 PF14584.6 CBZ25863.1 - 2.1 8.3 7.2 0.29 11.1 1.3 2.3 2 1 1 3 3 3 0 Protein of unknown function (DUF4446) Flu_NS2 PF00601.19 CBZ25863.1 - 2.5 8.4 8.1 8.6 6.7 1.9 2.3 1 1 1 2 2 2 0 Influenza non-structural protein (NS2) Ly49 PF08391.10 CBZ25863.1 - 2.6 8.4 5.9 1.5 9.2 1.5 2.4 2 1 1 3 3 3 0 Ly49-like protein, N-terminal region Enkurin PF13864.6 CBZ25863.1 - 4.8 7.7 14.8 4.2 7.9 12.3 2.0 2 0 0 2 2 2 0 Calmodulin-binding Spc7 PF08317.11 CBZ25863.1 - 6.6 5.5 18.7 1.9 7.3 15.1 1.7 2 0 0 2 2 2 0 Spc7 kinetochore protein DUF1043 PF06295.12 CBZ25863.1 - 8.1 6.5 9.4 6.6 6.8 5.8 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1043) DP PF08781.10 CBZ25863.1 - 9 6.2 17.0 5.4 6.9 7.5 2.4 1 1 1 2 2 2 0 Transcription factor DP Paf67 PF10255.9 CBZ25864.1 - 2.6e-49 168.3 0.0 6.1e-49 167.1 0.0 1.6 1 1 0 1 1 1 1 RNA polymerase I-associated factor PAF67 FGGY_N PF00370.21 CBZ25865.1 - 3.3e-76 256.1 0.0 4.5e-76 255.6 0.0 1.2 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain FGGY_C PF02782.16 CBZ25865.1 - 1.5e-30 106.5 0.0 2.5e-30 105.7 0.0 1.4 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain BcrAD_BadFG PF01869.20 CBZ25865.1 - 0.019 14.4 0.0 2.5 7.5 0.0 2.8 3 0 0 3 3 3 0 BadF/BadG/BcrA/BcrD ATPase family DUF1609 PF07753.11 CBZ25865.1 - 0.16 11.5 0.0 0.27 10.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1609) CH PF00307.31 CBZ25866.1 - 0.018 15.2 0.0 30 4.9 0.0 3.3 3 0 0 3 3 3 0 Calponin homology (CH) domain DUF4281 PF14108.6 CBZ25866.1 - 0.48 10.8 2.8 0.37 11.2 0.6 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4281) TFIIS_M PF07500.14 CBZ25867.1 - 2.1e-05 25.0 0.5 4e-05 24.1 0.5 1.5 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS), central domain Cys_rich_KTR PF14205.6 CBZ25867.1 - 0.15 11.9 0.2 0.27 11.1 0.2 1.5 1 0 0 1 1 1 0 Cysteine-rich KTR NUDIX PF00293.28 CBZ25869.1 - 9.4e-12 45.1 0.0 1.6e-11 44.3 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain LOB PF03195.14 CBZ25869.1 - 0.0077 16.8 0.0 0.018 15.6 0.0 1.7 1 0 0 1 1 1 1 Lateral organ boundaries (LOB) domain ESCRT-II PF05871.12 CBZ25870.1 - 1.3e-12 48.2 0.0 9.7e-12 45.3 0.0 2.0 1 1 0 1 1 1 1 ESCRT-II complex subunit DUF3223 PF11523.8 CBZ25870.1 - 0.091 13.6 0.1 0.97 10.3 0.0 2.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3223) Proteasome PF00227.26 CBZ25871.1 - 3.8e-27 95.0 0.0 4.6e-27 94.7 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit RNase_HII PF01351.18 CBZ25873.1 - 2.9e-19 69.7 0.0 8.6e-11 42.0 0.0 2.3 2 0 0 2 2 2 2 Ribonuclease HII Nop10p PF04135.12 CBZ25874.1 - 2.4e-21 75.5 0.3 3e-21 75.2 0.3 1.1 1 0 0 1 1 1 1 Nucleolar RNA-binding protein, Nop10p family IQ PF00612.27 CBZ25875.1 - 0.27 11.1 2.7 1.7 8.7 2.7 2.3 1 0 0 1 1 1 0 IQ calmodulin-binding motif EMC3_TMCO1 PF01956.16 CBZ25876.1 - 5.1e-47 159.8 4.9 5.1e-47 159.8 4.9 1.4 2 0 0 2 2 2 1 Integral membrane protein EMC3/TMCO1-like PIP5K PF01504.18 CBZ25877.1 - 1.4e-56 191.7 0.0 2.5e-56 190.9 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase DUF2749 PF10907.8 CBZ25877.1 - 0.062 13.5 0.0 0.14 12.4 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2749) Orbi_VP4 PF05059.12 CBZ25877.1 - 0.09 10.8 0.0 0.15 10.1 0.0 1.2 1 0 0 1 1 1 0 Orbivirus VP4 core protein DB_JBP1 PF18526.1 CBZ25879.1 - 0.00063 19.7 0.0 0.0016 18.4 0.0 1.6 1 0 0 1 1 1 1 Thymine dioxygenase JBP1 DNA-binding domain AF-4 PF05110.13 CBZ25879.1 - 0.0046 15.1 18.2 0.0059 14.8 18.2 1.1 1 0 0 1 1 1 1 AF-4 proto-oncoprotein Spore_coat_CotO PF14153.6 CBZ25879.1 - 0.17 11.8 1.9 0.34 10.8 1.9 1.4 1 0 0 1 1 1 0 Spore coat protein CotO Pex14_N PF04695.13 CBZ25879.1 - 0.83 10.3 9.8 0.36 11.5 6.6 2.2 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region FAM199X PF15814.5 CBZ25879.1 - 1.4 7.9 16.3 2.4 7.2 16.3 1.3 1 0 0 1 1 1 0 Protein family FAM199X Macoilin PF09726.9 CBZ25879.1 - 1.4 7.3 5.9 1.8 7.0 5.9 1.1 1 0 0 1 1 1 0 Macoilin family Apt1 PF10351.9 CBZ25879.1 - 2.3 7.0 10.3 3.3 6.5 10.3 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain DUF4614 PF15391.6 CBZ25879.1 - 3 7.8 13.1 5.8 6.9 13.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) PDZ_2 PF13180.6 CBZ25880.1 - 4.7e-05 23.6 0.0 0.00012 22.4 0.0 1.7 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 CBZ25880.1 - 0.00047 20.4 0.0 0.0011 19.3 0.0 1.6 1 0 0 1 1 1 1 PDZ domain NR_Repeat PF14046.6 CBZ25880.1 - 0.066 13.4 0.1 0.18 12.0 0.1 1.7 1 0 0 1 1 1 0 Nuclear receptor repeat DUF4423 PF14394.6 CBZ25880.1 - 0.46 10.2 4.6 0.95 9.1 1.6 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4423) Noelin-1 PF12308.8 CBZ25880.1 - 1.7 8.7 5.3 1.1 9.2 1.8 2.5 1 1 1 3 3 3 0 Neurogenesis glycoprotein BMFP PF04380.13 CBZ25880.1 - 6 7.4 7.9 5.9 7.5 0.1 3.1 2 1 1 3 3 3 0 Membrane fusogenic activity ArnB_C PF18677.1 CBZ25881.1 - 0.018 15.1 3.8 0.038 14.1 3.8 1.5 1 0 0 1 1 1 0 Archaellum regulatory network B, C-terminal domain DUF2972 PF11186.8 CBZ25881.1 - 0.29 11.0 2.5 2.5 8.0 1.7 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2972) Aa_trans PF01490.18 CBZ25882.1 - 1.2e-60 205.4 17.7 1.4e-60 205.2 17.7 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 CBZ25882.1 - 1.8e-06 27.2 12.5 1.8e-06 27.2 12.5 2.1 3 0 0 3 3 3 1 Tryptophan/tyrosine permease family TMEM70 PF06979.12 CBZ25882.1 - 0.19 12.2 12.1 1.5 9.2 0.1 3.4 2 1 1 3 3 3 0 Assembly, mitochondrial proton-transport ATP synth complex TFIIA_gamma_C PF02751.14 CBZ25883.1 - 0.0011 19.1 0.0 0.0018 18.4 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit TFIIA_gamma_N PF02268.16 CBZ25883.1 - 0.063 13.3 0.0 0.1 12.7 0.0 1.4 1 0 0 1 1 1 0 Transcription initiation factor IIA, gamma subunit, helical domain DUF1634 PF07843.11 CBZ25884.1 - 0.15 12.1 0.2 0.55 10.3 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1634) W2 PF02020.18 CBZ25884.1 - 0.27 11.4 1.0 1.5 9.0 0.0 2.6 3 0 0 3 3 3 0 eIF4-gamma/eIF5/eIF2-epsilon Sec1 PF00995.23 CBZ25886.1 - 3e-103 347.0 0.2 4e-103 346.6 0.2 1.2 1 0 0 1 1 1 1 Sec1 family Dus PF01207.17 CBZ25887.1 - 8.5e-37 126.9 0.3 2.1e-32 112.5 0.0 2.2 2 0 0 2 2 2 2 Dihydrouridine synthase (Dus) DEP PF00610.21 CBZ25887.1 - 0.18 11.9 0.0 0.41 10.7 0.0 1.5 1 0 0 1 1 1 0 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) zf-ANAPC11 PF12861.7 CBZ25888.1 - 0.021 14.8 0.8 0.039 14.0 0.8 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C2HC_2 PF13913.6 CBZ25889.1 - 1.2e-15 56.9 6.1 2.5e-10 40.0 1.3 2.3 2 0 0 2 2 2 2 zinc-finger of a C2HC-type zf-H2C2_2 PF13465.6 CBZ25889.1 - 0.013 15.9 0.4 7.7 7.1 0.0 2.3 2 0 0 2 2 2 0 Zinc-finger double domain zf-C2H2_6 PF13912.6 CBZ25889.1 - 0.031 14.3 2.2 3.1 7.9 0.2 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2_4 PF13894.6 CBZ25889.1 - 0.043 14.7 1.3 9.9 7.3 0.4 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2 PF00096.26 CBZ25889.1 - 0.25 11.9 3.3 20 5.9 1.6 2.5 2 0 0 2 2 2 0 Zinc finger, C2H2 type DnaJ PF00226.31 CBZ25890.1 - 2.3e-21 75.7 2.0 7e-21 74.1 0.6 2.4 2 0 0 2 2 2 1 DnaJ domain TPR_2 PF07719.17 CBZ25890.1 - 1.4e-19 68.6 19.5 0.00028 20.8 0.1 8.2 8 1 0 8 8 8 4 Tetratricopeptide repeat TPR_19 PF14559.6 CBZ25890.1 - 2.2e-12 47.3 17.8 0.0017 18.8 0.6 6.7 4 3 2 6 6 6 4 Tetratricopeptide repeat TPR_1 PF00515.28 CBZ25890.1 - 5.9e-11 41.7 22.0 0.0023 17.7 0.0 7.3 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_14 PF13428.6 CBZ25890.1 - 7.3e-10 38.8 17.0 0.041 14.7 0.0 7.1 5 1 2 7 7 6 2 Tetratricopeptide repeat TPR_9 PF13371.6 CBZ25890.1 - 5.6e-09 36.0 14.7 0.014 15.5 0.6 5.8 3 2 1 5 5 5 3 Tetratricopeptide repeat TPR_16 PF13432.6 CBZ25890.1 - 9.2e-08 32.6 18.7 0.00025 21.6 2.8 5.6 3 2 2 6 6 6 4 Tetratricopeptide repeat TPR_17 PF13431.6 CBZ25890.1 - 2e-07 30.9 11.1 0.0011 19.2 0.1 6.2 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_11 PF13414.6 CBZ25890.1 - 2.2e-07 30.5 20.6 2.3e-05 23.9 0.4 5.6 6 2 1 7 7 6 3 TPR repeat TPR_8 PF13181.6 CBZ25890.1 - 4.9e-07 29.5 13.1 0.055 13.7 0.1 6.3 7 0 0 7 7 6 2 Tetratricopeptide repeat TPR_12 PF13424.6 CBZ25890.1 - 3.1e-05 24.2 17.8 0.0029 17.8 1.5 5.7 4 2 2 6 6 6 1 Tetratricopeptide repeat ANAPC3 PF12895.7 CBZ25890.1 - 0.00017 21.7 11.2 0.0043 17.2 0.1 4.4 2 2 0 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_10 PF13374.6 CBZ25890.1 - 0.0038 17.0 0.2 0.0038 17.0 0.2 5.1 6 0 0 6 6 4 1 Tetratricopeptide repeat TPR_7 PF13176.6 CBZ25890.1 - 0.021 14.8 10.8 15 5.9 0.0 5.5 6 0 0 6 6 6 0 Tetratricopeptide repeat 3HCDH_RFF PF18321.1 CBZ25890.1 - 0.032 14.7 0.1 0.33 11.4 0.0 2.6 1 1 1 2 2 2 0 3-hydroxybutyryl-CoA dehydrogenase reduced Rossmann-fold domain LPD7 PF18821.1 CBZ25890.1 - 0.058 13.5 3.5 0.82 9.8 0.1 3.1 3 0 0 3 3 3 0 Large polyvalent protein-associated domain 7 Fis1_TPR_C PF14853.6 CBZ25890.1 - 0.21 11.7 4.2 1.1 9.4 0.3 3.6 3 0 0 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat SHNi-TPR PF10516.9 CBZ25890.1 - 2.3 7.7 6.6 18 4.9 0.0 3.5 4 0 0 4 4 4 0 SHNi-TPR DUF3856 PF12968.7 CBZ25890.1 - 5 7.2 9.0 4.4 7.4 1.1 4.1 2 2 1 3 3 3 0 Domain of Unknown Function (DUF3856) DUF4407 PF14362.6 CBZ25890.1 - 5.3 6.3 10.4 11 5.3 10.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Mito_carr PF00153.27 CBZ25891.1 - 2.8e-87 286.8 23.8 1e-20 73.4 0.0 6.6 6 1 1 7 7 7 6 Mitochondrial carrier protein Serine_protease PF18405.1 CBZ25891.1 - 0.00061 19.0 5.1 0.82 8.8 0.0 4.2 5 0 0 5 5 5 3 Gammaproteobacterial serine protease ThrE PF06738.12 CBZ25891.1 - 0.16 11.3 2.7 0.2 11.0 0.6 2.3 2 1 0 2 2 2 0 Putative threonine/serine exporter PP2C PF00481.21 CBZ25893.1 - 4.8e-69 232.9 1.1 6e-69 232.5 1.1 1.0 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 CBZ25893.1 - 0.0007 19.3 0.1 0.0013 18.4 0.1 1.5 1 1 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.12 CBZ25893.1 - 0.0037 17.2 0.1 0.4 10.6 0.0 2.3 2 1 0 2 2 2 2 Stage II sporulation protein E (SpoIIE) LSM PF01423.22 CBZ25894.1 - 5.4e-08 32.4 0.1 7.7e-08 31.9 0.1 1.3 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 CBZ25894.1 - 0.0045 17.1 0.4 0.021 14.9 0.0 2.2 3 0 0 3 3 3 1 Ataxin 2 SM domain LSM14 PF12701.7 CBZ25894.1 - 0.041 14.0 0.0 0.11 12.7 0.0 1.7 1 1 0 1 1 1 0 Scd6-like Sm domain DUF5623 PF18536.1 CBZ25895.1 - 0.0044 17.3 0.0 0.0097 16.2 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF5623) ubiquitin PF00240.23 CBZ25896.1 - 6.8e-16 57.8 0.1 1.3e-15 56.9 0.1 1.5 1 0 0 1 1 1 1 Ubiquitin family UBA PF00627.31 CBZ25896.1 - 5.5e-06 26.2 0.8 1.2e-05 25.1 0.8 1.7 1 0 0 1 1 1 1 UBA/TS-N domain Rad60-SLD PF11976.8 CBZ25896.1 - 0.00014 21.7 0.1 0.00023 20.9 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ComX PF05952.12 CBZ25896.1 - 0.0032 17.4 1.2 0.0084 16.0 1.2 1.7 1 0 0 1 1 1 1 Bacillus competence pheromone ComX RNA_pol_Rpb5_C PF01191.19 CBZ25896.1 - 0.014 15.3 0.1 0.031 14.1 0.1 1.5 1 0 0 1 1 1 0 RNA polymerase Rpb5, C-terminal domain XPC-binding PF09280.11 CBZ25896.1 - 0.031 14.0 17.1 0.1 12.3 17.1 2.0 1 0 0 1 1 1 0 XPC-binding domain DUF2407 PF10302.9 CBZ25896.1 - 0.034 14.7 0.0 0.059 13.9 0.0 1.4 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain Ubiquitin_5 PF18037.1 CBZ25896.1 - 0.041 14.2 0.1 0.069 13.5 0.1 1.3 1 0 0 1 1 1 0 Ubiquitin-like domain Rad60-SLD_2 PF13881.6 CBZ25896.1 - 0.059 13.5 0.1 0.14 12.3 0.1 1.6 1 1 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 CBZ25896.1 - 0.074 13.5 0.0 0.21 12.1 0.0 1.8 1 1 0 1 1 1 0 Ubiquitin-like domain Pol_alpha_B_N PF08418.10 CBZ25896.1 - 0.12 12.4 1.2 0.15 12.0 0.5 1.6 1 1 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal HOIP-UBA PF16678.5 CBZ25896.1 - 0.13 12.3 0.7 0.34 10.9 0.1 1.9 2 0 0 2 2 2 0 HOIP UBA domain pair TFIIA PF03153.13 CBZ25896.1 - 1.4 8.8 14.7 1.7 8.5 14.7 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit GerD PF17898.1 CBZ25896.1 - 3 7.8 16.8 7.9 6.5 14.9 2.4 2 1 0 2 2 2 0 Spore germination GerD central core domain STI1 PF17830.1 CBZ25896.1 - 6.2 6.8 24.2 0.47 10.4 10.7 2.7 1 1 1 2 2 2 0 STI1 domain Pkinase PF00069.25 CBZ25897.1 - 1.9e-79 266.7 0.0 2.2e-79 266.5 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ25897.1 - 2e-35 122.3 0.0 4.3e-35 121.2 0.0 1.4 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.23 CBZ25897.1 - 0.0009 19.2 0.3 0.02 14.8 0.0 2.4 2 1 1 3 3 3 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 CBZ25897.1 - 0.014 14.4 0.0 0.074 12.0 0.0 1.9 1 1 0 1 1 1 0 Haspin like kinase domain RIO1 PF01163.22 CBZ25897.1 - 0.2 11.2 0.0 0.38 10.3 0.0 1.5 1 1 0 1 1 1 0 RIO1 family ZapB PF06005.12 CBZ25898.1 - 0.23 11.9 31.1 0.056 13.9 2.8 5.4 1 1 3 4 4 4 0 Cell division protein ZapB Val_tRNA-synt_C PF10458.9 CBZ25898.1 - 0.33 11.3 0.2 0.33 11.3 0.2 4.2 4 2 0 4 4 4 0 Valyl tRNA synthetase tRNA binding arm PfUIS3 PF11567.8 CBZ25898.1 - 0.85 10.0 7.5 0.78 10.1 1.2 3.1 2 1 1 3 3 3 0 Plasmodium falciparum UIS3 membrane protein DUF3450 PF11932.8 CBZ25898.1 - 1 8.6 23.7 0.58 9.4 2.0 3.4 1 1 2 3 3 3 0 Protein of unknown function (DUF3450) FlxA PF14282.6 CBZ25898.1 - 1.9 8.5 15.8 1.6 8.8 3.7 3.8 2 2 2 4 4 4 0 FlxA-like protein DUF4407 PF14362.6 CBZ25898.1 - 2.6 7.3 23.5 4.5e+02 -0.0 23.5 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) YabA PF06156.13 CBZ25898.1 - 4.1 8.1 21.9 0.82 10.3 2.8 3.9 2 1 2 4 4 4 0 Initiation control protein YabA V_ATPase_I PF01496.19 CBZ25898.1 - 5.2 4.8 11.5 6.5 4.5 11.5 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family GTP_EFTU PF00009.27 CBZ25899.1 - 3.5e-62 209.4 0.0 5.6e-62 208.7 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_II PF14492.6 CBZ25899.1 - 4.3e-24 84.4 0.0 9.9e-24 83.2 0.0 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_C PF00679.24 CBZ25899.1 - 7.4e-21 74.0 0.1 2e-20 72.6 0.1 1.8 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_IV PF03764.18 CBZ25899.1 - 2.2e-18 66.2 0.0 5.5e-18 64.9 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G, domain IV GTP_EFTU_D2 PF03144.25 CBZ25899.1 - 2.4e-07 31.1 0.0 9.2e-07 29.2 0.0 2.0 1 0 0 1 1 1 1 Elongation factor Tu domain 2 RF3_C PF16658.5 CBZ25899.1 - 2.5e-05 24.1 0.1 0.00012 21.9 0.1 2.1 1 0 0 1 1 1 1 Class II release factor RF3, C-terminal domain MMR_HSR1 PF01926.23 CBZ25899.1 - 0.0037 17.3 0.0 0.0081 16.2 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase AIG1 PF04548.16 CBZ25899.1 - 0.017 14.4 0.0 0.037 13.4 0.0 1.5 1 0 0 1 1 1 0 AIG1 family DUF4132 PF13569.6 CBZ25899.1 - 0.083 12.7 0.0 0.17 11.7 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4132) FeoB_N PF02421.18 CBZ25899.1 - 0.09 12.3 0.1 0.77 9.3 0.0 2.4 2 1 0 2 2 2 0 Ferrous iron transport protein B DUF442 PF04273.13 CBZ25899.1 - 0.11 12.6 0.1 3.5 7.8 0.0 2.9 2 1 1 3 3 3 0 Putative phosphatase (DUF442) AvrPtoB_bdg PF16847.5 CBZ25899.1 - 0.12 12.9 0.0 2.1 8.9 0.0 2.6 3 0 0 3 3 2 0 Avirulence AvrPtoB, BAK1-binding domain WD40 PF00400.32 CBZ25900.1 - 2.9e-07 31.1 7.6 0.0095 16.8 0.1 5.3 5 0 0 5 5 5 3 WD domain, G-beta repeat Ge1_WD40 PF16529.5 CBZ25900.1 - 0.003 16.6 0.6 0.046 12.7 0.0 2.8 2 1 1 3 3 3 1 WD40 region of Ge1, enhancer of mRNA-decapping protein CRAL_TRIO PF00650.20 CBZ25901.1 - 8.7e-25 87.3 0.0 1.4e-24 86.6 0.0 1.4 1 0 0 1 1 1 1 CRAL/TRIO domain CAP_GLY PF01302.25 CBZ25901.1 - 4e-11 42.8 0.6 6.5e-11 42.1 0.6 1.4 1 0 0 1 1 1 1 CAP-Gly domain CRAL_TRIO_N PF03765.15 CBZ25901.1 - 0.093 12.9 0.2 0.18 12.0 0.2 1.5 1 0 0 1 1 1 0 CRAL/TRIO, N-terminal domain IF4E PF01652.18 CBZ25902.1 - 2.7e-09 37.0 0.0 3.3e-09 36.7 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E Ribosomal_S27 PF01599.19 CBZ25903.1 - 5e-23 81.0 4.0 9.4e-23 80.1 4.0 1.5 1 0 0 1 1 1 1 Ribosomal protein S27a ubiquitin PF00240.23 CBZ25903.1 - 3e-10 39.7 0.1 1.7e-09 37.3 0.0 2.2 2 1 0 2 2 2 1 Ubiquitin family Rad60-SLD PF11976.8 CBZ25903.1 - 2.2e-06 27.4 0.2 2.5e-05 24.0 0.0 2.4 2 1 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like IBR PF01485.21 CBZ25903.1 - 0.0044 17.2 0.7 0.0078 16.4 0.7 1.4 1 0 0 1 1 1 1 IBR domain, a half RING-finger domain DnaJ PF00226.31 CBZ25904.1 - 1.5e-22 79.4 0.5 3.4e-22 78.3 0.5 1.6 1 0 0 1 1 1 1 DnaJ domain ATP-synt_Eps PF04627.13 CBZ25905.1 - 4.3e-07 29.8 0.3 6.9e-07 29.2 0.3 1.3 1 0 0 1 1 1 1 Mitochondrial ATP synthase epsilon chain DUF3592 PF12158.8 CBZ25906.1 - 8.1e-20 71.4 0.7 9.2e-20 71.2 0.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3592) RNase_HII PF01351.18 CBZ25907.1 - 8.3e-34 117.2 0.0 1.1e-33 116.8 0.0 1.2 1 0 0 1 1 1 1 Ribonuclease HII PIG-U PF06728.13 CBZ25908.1 - 1.6e-06 27.4 21.4 2.6e-05 23.5 21.4 2.2 1 1 0 1 1 1 1 GPI transamidase subunit PIG-U EamA PF00892.20 CBZ25910.1 - 2e-06 28.0 32.0 0.00012 22.3 3.8 4.5 5 0 0 5 5 5 3 EamA-like transporter family UAA PF08449.11 CBZ25910.1 - 5.5e-06 25.8 12.6 0.00032 20.0 12.6 2.2 1 1 0 1 1 1 1 UAA transporter family CRT-like PF08627.10 CBZ25910.1 - 5.3e-05 22.3 13.8 0.0001 21.4 13.8 1.4 1 1 0 1 1 1 1 CRT-like, chloroquine-resistance transporter-like SSB PF00436.25 CBZ25913.1 - 1.2e-05 25.3 0.0 1.8e-05 24.7 0.0 1.3 1 0 0 1 1 1 1 Single-strand binding protein family tRNA_anti-codon PF01336.25 CBZ25913.1 - 0.051 13.6 0.0 0.11 12.5 0.0 1.7 1 1 0 1 1 1 0 OB-fold nucleic acid binding domain LRR_9 PF14580.6 CBZ25914.1 - 7.5e-13 48.3 0.1 3.3e-12 46.3 0.1 2.1 1 1 1 2 2 2 1 Leucine-rich repeat LRR_4 PF12799.7 CBZ25914.1 - 8.6e-08 32.4 0.6 0.018 15.4 0.1 3.1 3 1 0 3 3 3 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CBZ25914.1 - 7.2e-07 28.9 0.4 4.7e-05 23.1 0.1 2.7 1 1 1 2 2 2 2 Leucine rich repeat Ribosomal_60s PF00428.19 CBZ25914.1 - 5.2 7.7 7.8 1.2 9.8 4.2 1.8 2 0 0 2 2 2 0 60s Acidic ribosomal protein Pkinase PF00069.25 CBZ25915.1 - 3.2e-67 226.7 0.0 3.9e-67 226.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ25915.1 - 2.5e-34 118.7 0.0 3.3e-34 118.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CBZ25915.1 - 0.0023 17.3 0.0 0.0034 16.7 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 CBZ25915.1 - 0.0051 16.2 1.6 0.0092 15.4 1.6 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 CBZ25915.1 - 0.026 13.5 1.3 0.076 11.9 1.3 1.7 1 1 0 1 1 1 0 Haspin like kinase domain APH PF01636.23 CBZ25915.1 - 0.054 13.4 0.1 0.12 12.3 0.1 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family Torus PF16131.5 CBZ25916.1 - 1.3e-06 29.1 5.9 0.0016 19.1 0.2 3.3 3 0 0 3 3 3 2 Torus domain zf-CCCH_4 PF18044.1 CBZ25916.1 - 0.0026 17.5 14.5 0.0035 17.1 2.8 3.5 3 0 0 3 3 3 2 CCCH-type zinc finger DUF459 PF04311.13 CBZ25916.1 - 0.0045 16.0 3.0 0.0073 15.3 3.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF459) zf-CCCH PF00642.24 CBZ25916.1 - 0.028 14.3 17.4 0.054 13.4 0.4 3.3 3 0 0 3 3 3 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 CBZ25916.1 - 9 6.5 24.6 0.67 10.1 2.6 3.7 4 0 0 4 4 4 0 Zinc finger domain Torus PF16131.5 CBZ25917.1 - 9.4e-05 23.1 11.3 0.00023 21.8 0.1 3.9 4 0 0 4 4 4 2 Torus domain zf-CCCH_4 PF18044.1 CBZ25917.1 - 0.0012 18.6 1.8 0.0026 17.5 1.8 1.6 1 0 0 1 1 1 1 CCCH-type zinc finger zf_CCCH_4 PF18345.1 CBZ25917.1 - 0.0077 16.3 1.2 0.0077 16.3 1.2 3.0 3 0 0 3 3 3 1 Zinc finger domain XPC-binding PF09280.11 CBZ25918.1 - 0.0003 20.5 0.0 0.00095 18.9 0.0 1.9 2 0 0 2 2 2 1 XPC-binding domain BUD22 PF09073.10 CBZ25918.1 - 1.1 8.5 7.7 2 7.7 7.7 1.3 1 0 0 1 1 1 0 BUD22 TPR_1 PF00515.28 CBZ25919.1 - 5.3e-13 48.2 10.8 1.7e-05 24.4 0.0 6.6 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_11 PF13414.6 CBZ25919.1 - 2.1e-12 46.5 1.9 8.4e-05 22.2 0.0 4.7 4 0 0 4 4 4 3 TPR repeat TPR_2 PF07719.17 CBZ25919.1 - 1.4e-11 43.5 28.0 0.0024 17.9 0.0 8.0 8 0 0 8 8 8 3 Tetratricopeptide repeat DnaJ PF00226.31 CBZ25919.1 - 3.3e-09 36.7 0.3 1.1e-08 35.0 0.1 2.0 2 0 0 2 2 2 1 DnaJ domain TPR_9 PF13371.6 CBZ25919.1 - 3.3e-05 23.9 25.3 0.3 11.3 0.9 6.1 4 2 1 5 5 5 3 Tetratricopeptide repeat TPR_8 PF13181.6 CBZ25919.1 - 8.6e-05 22.5 5.6 0.72 10.2 0.0 5.6 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_7 PF13176.6 CBZ25919.1 - 0.00012 21.8 6.4 0.84 9.8 0.2 4.9 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_17 PF13431.6 CBZ25919.1 - 0.0005 20.3 3.2 2.8 8.5 0.0 4.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 CBZ25919.1 - 0.00078 20.1 38.9 0.11 13.3 0.2 8.0 4 2 3 7 7 7 3 Tetratricopeptide repeat TPR_12 PF13424.6 CBZ25919.1 - 0.0065 16.7 4.5 0.0065 16.7 4.5 5.8 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_16 PF13432.6 CBZ25919.1 - 3.3 8.4 43.2 0.3 11.7 1.5 6.3 7 0 0 7 7 5 0 Tetratricopeptide repeat Peptidase_C2 PF00648.21 CBZ25921.1 - 6.7e-22 77.9 0.0 9.9e-22 77.3 0.0 1.2 1 0 0 1 1 1 1 Calpain family cysteine protease HD_2 PF12917.7 CBZ25921.1 - 0.033 13.9 0.4 0.061 13.1 0.4 1.3 1 0 0 1 1 1 0 HD containing hydrolase-like enzyme Tfb2 PF03849.14 CBZ25923.1 - 8.6e-23 80.9 0.0 1.2e-22 80.4 0.0 1.2 1 0 0 1 1 1 1 Transcription factor Tfb2 Helicase_C_3 PF13625.6 CBZ25923.1 - 9.5e-07 29.0 0.2 6.6e-06 26.3 0.0 2.4 3 0 0 3 3 3 1 Helicase conserved C-terminal domain Tfb2_C PF18307.1 CBZ25923.1 - 0.082 13.3 0.3 0.16 12.4 0.3 1.5 1 0 0 1 1 1 0 Transcription factor Tfb2 (p52) C-terminal domain Arf PF00025.21 CBZ25925.1 - 4.1e-30 104.5 0.0 5.9e-30 104.0 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.20 CBZ25925.1 - 5e-09 35.8 0.0 3.3e-08 33.1 0.0 2.0 2 1 1 3 3 3 1 G-protein alpha subunit Ras PF00071.22 CBZ25925.1 - 2.5e-08 33.7 0.0 3.8e-08 33.1 0.0 1.4 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CBZ25925.1 - 5.2e-08 33.1 0.0 9e-08 32.4 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 CBZ25925.1 - 1.6e-05 24.5 0.0 2.6e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit cNMP_binding PF00027.29 CBZ25926.1 - 9.1e-18 64.1 0.1 6.6e-10 38.9 0.1 4.9 4 0 0 4 4 4 2 Cyclic nucleotide-binding domain C2 PF00168.30 CBZ25926.1 - 2.1e-10 40.8 0.0 0.0011 19.2 0.0 4.5 4 0 0 4 4 4 2 C2 domain UPF0261 PF06792.11 CBZ25926.1 - 0.058 12.3 0.1 0.11 11.4 0.1 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0261) Torus PF16131.5 CBZ25927.1 - 2.2e-07 31.5 1.0 0.00044 20.9 0.0 2.6 2 0 0 2 2 2 2 Torus domain zf-CCCH PF00642.24 CBZ25927.1 - 0.047 13.6 10.4 0.21 11.5 0.3 3.1 3 0 0 3 3 3 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Rimk_N PF18030.1 CBZ25928.1 - 0.15 12.4 0.3 0.38 11.2 0.0 1.7 2 0 0 2 2 2 0 RimK PreATP-grasp domain DivIC PF04977.15 CBZ25928.1 - 5.2 6.9 9.7 1.8 8.4 0.6 2.7 2 1 0 2 2 2 0 Septum formation initiator Pkinase PF00069.25 CBZ25929.1 - 3.7e-57 193.7 0.0 4.8e-57 193.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ25929.1 - 1.8e-31 109.4 0.0 2.5e-31 108.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CBZ25929.1 - 0.00017 20.5 0.0 0.00027 19.9 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 CBZ25929.1 - 0.045 13.7 0.1 0.27 11.1 0.0 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family Kinase-like PF14531.6 CBZ25929.1 - 0.16 11.3 0.0 0.27 10.5 0.0 1.3 1 0 0 1 1 1 0 Kinase-like HA2 PF04408.23 CBZ25930.1 - 2.1e-17 63.3 0.0 7.6e-17 61.6 0.0 2.0 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.31 CBZ25930.1 - 1.8e-15 57.3 0.0 7.7e-15 55.2 0.0 2.1 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 CBZ25930.1 - 2.8e-09 37.0 0.0 8e-09 35.5 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_22 PF13401.6 CBZ25930.1 - 0.001 19.4 0.3 0.0092 16.3 0.3 2.5 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 CBZ25930.1 - 0.0027 18.1 0.0 0.015 15.7 0.0 2.3 1 1 0 1 1 1 1 AAA domain T2SSE PF00437.20 CBZ25930.1 - 0.0049 16.0 0.0 0.0097 15.0 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein ATPase PF06745.13 CBZ25930.1 - 0.017 14.5 0.0 0.034 13.5 0.0 1.5 1 0 0 1 1 1 0 KaiC PhoH PF02562.16 CBZ25930.1 - 0.031 13.7 0.0 0.077 12.4 0.0 1.6 1 0 0 1 1 1 0 PhoH-like protein ResIII PF04851.15 CBZ25930.1 - 0.035 14.1 0.0 0.96 9.4 0.0 2.4 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit NACHT PF05729.12 CBZ25930.1 - 0.043 13.7 0.0 0.59 10.0 0.0 2.4 2 0 0 2 2 2 0 NACHT domain AAA_23 PF13476.6 CBZ25930.1 - 0.046 14.2 0.2 0.16 12.5 0.0 2.0 1 1 0 1 1 1 0 AAA domain AAA_33 PF13671.6 CBZ25930.1 - 0.076 13.2 0.2 1.5 8.9 0.0 2.7 2 0 0 2 2 2 0 AAA domain Sigma54_activat PF00158.26 CBZ25930.1 - 0.091 12.5 0.0 0.65 9.7 0.0 2.2 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_7 PF12775.7 CBZ25930.1 - 0.12 11.8 0.0 0.32 10.5 0.0 1.6 1 0 0 1 1 1 0 P-loop containing dynein motor region ABC_tran PF00005.27 CBZ25930.1 - 0.13 12.8 0.0 0.35 11.4 0.0 1.7 1 0 0 1 1 1 0 ABC transporter Peptidase_S66 PF02016.15 CBZ25930.1 - 0.14 12.2 1.2 21 5.2 0.2 3.2 2 1 0 2 2 2 0 LD-carboxypeptidase N-terminal domain cobW PF02492.19 CBZ25930.1 - 0.16 11.6 0.1 2.1 7.9 0.0 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain RsgA_GTPase PF03193.16 CBZ25930.1 - 0.17 11.8 0.0 0.37 10.7 0.0 1.6 1 0 0 1 1 1 0 RsgA GTPase Pox_A32 PF04665.12 CBZ25930.1 - 0.23 10.9 0.0 0.52 9.7 0.0 1.5 2 0 0 2 2 2 0 Poxvirus A32 protein NifU PF01106.17 CBZ25931.1 - 1.6e-24 85.8 0.1 2.9e-24 85.0 0.1 1.4 1 0 0 1 1 1 1 NifU-like domain Nfu_N PF08712.11 CBZ25931.1 - 2.7e-13 49.8 0.0 8.6e-13 48.2 0.0 1.8 2 0 0 2 2 2 1 Scaffold protein Nfu/NifU N terminal eIF-6 PF01912.18 CBZ25932.1 - 8.5e-79 263.5 0.5 1.3e-78 262.9 0.4 1.3 2 0 0 2 2 2 1 eIF-6 family Pkinase PF00069.25 CBZ25933.1 - 8.9e-73 244.9 0.0 1.3e-72 244.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ25933.1 - 3.1e-38 131.6 0.0 4.3e-38 131.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CBZ25933.1 - 1.2e-06 28.0 0.0 2e-06 27.4 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 CBZ25933.1 - 0.0014 18.0 0.1 0.003 17.0 0.1 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.9 CBZ25933.1 - 0.0038 16.8 0.2 0.0063 16.1 0.2 1.2 1 0 0 1 1 1 1 PhoP regulatory network protein YrbL APH PF01636.23 CBZ25933.1 - 0.0057 16.6 0.1 0.83 9.5 0.0 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family RIO1 PF01163.22 CBZ25933.1 - 0.018 14.7 0.1 0.03 13.9 0.1 1.3 1 0 0 1 1 1 0 RIO1 family Pkinase PF00069.25 CBZ25934.1 - 8.3e-50 169.6 0.0 1.4e-49 168.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ25934.1 - 6.9e-30 104.2 0.0 1.1e-29 103.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 CBZ25934.1 - 0.0019 18.2 0.7 0.0032 17.4 0.0 1.8 2 0 0 2 2 2 1 Phosphotransferase enzyme family Ribonuclease_3 PF00636.26 CBZ25935.1 - 0.0011 19.6 0.1 0.23 12.1 0.0 2.8 1 1 0 2 2 2 2 Ribonuclease III domain Ribosomal_S13 PF00416.22 CBZ25936.1 - 1.6e-43 148.2 0.4 1.8e-43 148.0 0.4 1.0 1 0 0 1 1 1 1 Ribosomal protein S13/S18 Ribosomal_S13 PF00416.22 CBZ25937.1 - 1.6e-43 148.2 0.4 1.8e-43 148.0 0.4 1.0 1 0 0 1 1 1 1 Ribosomal protein S13/S18 AAA_6 PF12774.7 CBZ25938.1 - 2.7e-152 506.4 0.0 1.9e-151 503.6 0.0 2.3 2 0 0 2 2 2 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 CBZ25938.1 - 3.9e-113 378.5 14.8 3.9e-113 378.5 14.8 4.0 5 0 0 5 5 5 1 Dynein heavy chain, N-terminal region 2 Dynein_C PF18199.1 CBZ25938.1 - 2.4e-102 342.3 0.0 2.4e-102 342.3 0.0 4.4 5 0 0 5 5 4 1 Dynein heavy chain C-terminal domain AAA_8 PF12780.7 CBZ25938.1 - 1.2e-98 329.6 0.1 2.3e-97 325.4 0.0 2.6 2 0 0 2 2 2 1 P-loop containing dynein motor region D4 AAA_9 PF12781.7 CBZ25938.1 - 7.4e-77 257.4 0.0 7.4e-77 257.4 0.0 3.7 4 0 0 4 4 4 1 ATP-binding dynein motor region AAA_7 PF12775.7 CBZ25938.1 - 6.6e-66 221.3 1.6 1.1e-63 214.0 0.0 3.0 3 0 0 3 3 3 1 P-loop containing dynein motor region AAA_lid_11 PF18198.1 CBZ25938.1 - 1e-51 175.0 0.0 4.3e-51 173.0 0.0 2.1 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain Dynein_heavy PF03028.15 CBZ25938.1 - 3.2e-47 159.5 0.3 4.3e-45 152.7 0.0 3.9 4 0 0 4 4 3 1 Dynein heavy chain region D6 P-loop domain MT PF12777.7 CBZ25938.1 - 3.5e-44 151.2 11.4 8e-44 150.1 11.4 1.6 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor Dynein_AAA_lid PF17852.1 CBZ25938.1 - 1.8e-24 86.3 0.3 1e-23 83.8 0.0 2.6 2 0 0 2 2 2 1 Dynein heavy chain AAA lid domain AAA_lid_1 PF17857.1 CBZ25938.1 - 4e-15 55.9 0.1 1.7e-14 53.8 0.0 2.1 2 0 0 2 2 1 1 AAA+ lid domain AAA_5 PF07728.14 CBZ25938.1 - 4.3e-15 55.9 0.1 0.00026 21.0 0.0 7.3 6 2 0 6 6 5 3 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 CBZ25938.1 - 4e-09 36.9 0.0 0.00016 22.0 0.0 4.4 4 0 0 4 4 3 2 AAA domain RNA_helicase PF00910.22 CBZ25938.1 - 9.7e-06 25.9 0.0 0.084 13.3 0.0 4.0 4 0 0 4 4 3 1 RNA helicase AAA PF00004.29 CBZ25938.1 - 2.4e-05 24.8 0.0 0.43 11.0 0.0 3.7 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 CBZ25938.1 - 0.00022 21.7 7.3 0.81 10.1 0.0 5.3 5 0 0 5 5 5 2 AAA ATPase domain NACHT PF05729.12 CBZ25938.1 - 0.00037 20.5 0.1 0.062 13.2 0.0 3.5 2 0 0 2 2 2 1 NACHT domain AAA_30 PF13604.6 CBZ25938.1 - 0.00071 19.4 0.0 0.96 9.1 0.0 3.1 2 0 0 2 2 2 1 AAA domain ATG16 PF08614.11 CBZ25938.1 - 0.00072 19.8 9.0 0.00072 19.8 9.0 3.9 4 0 0 4 4 4 1 Autophagy protein 16 (ATG16) AAA_18 PF13238.6 CBZ25938.1 - 0.019 15.5 4.4 1.4 9.5 0.0 5.3 6 0 0 6 6 4 0 AAA domain AAA_24 PF13479.6 CBZ25938.1 - 0.02 14.6 0.1 6.1 6.5 0.0 3.0 3 0 0 3 3 2 0 AAA domain AAA_14 PF13173.6 CBZ25938.1 - 0.093 12.8 0.0 12 5.9 0.0 2.9 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 CBZ25938.1 - 0.73 10.0 5.7 2.1 8.5 0.1 3.9 3 0 0 3 3 2 0 AAA domain Fib_alpha PF08702.10 CBZ25938.1 - 2 8.6 16.9 0.14 12.3 0.4 4.5 3 0 0 3 3 3 0 Fibrinogen alpha/beta chain family DUF1664 PF07889.12 CBZ25938.1 - 4.9 7.2 22.5 2.5 8.1 1.7 4.9 3 1 1 4 4 4 0 Protein of unknown function (DUF1664) Exonuc_VII_L PF02601.15 CBZ25938.1 - 7.2 6.1 30.1 0.3 10.6 2.5 4.1 4 0 0 4 4 4 0 Exonuclease VII, large subunit Filament PF00038.21 CBZ25938.1 - 7.7 6.0 37.9 0.071 12.7 6.4 4.1 3 0 0 3 3 3 0 Intermediate filament protein LrgA PF03788.14 CBZ25939.1 - 0.38 10.7 2.5 1 9.4 2.5 1.7 1 0 0 1 1 1 0 LrgA family CBM_4_9 PF02018.17 CBZ25940.1 - 0.075 13.3 0.0 0.14 12.4 0.0 1.3 1 0 0 1 1 1 0 Carbohydrate binding domain S10_plectin PF03501.15 CBZ25941.1 - 4.3e-35 119.7 0.0 5.2e-35 119.4 0.0 1.1 1 0 0 1 1 1 1 Plectin/S10 domain DUF5549 PF17703.1 CBZ25941.1 - 1.2 8.7 8.2 2.2 7.9 8.2 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5549) S10_plectin PF03501.15 CBZ25942.1 - 4.4e-35 119.6 0.0 5.2e-35 119.4 0.0 1.1 1 0 0 1 1 1 1 Plectin/S10 domain DUF5549 PF17703.1 CBZ25942.1 - 0.97 9.0 7.2 1.7 8.3 7.2 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5549) WD40 PF00400.32 CBZ25943.1 - 1.4e-11 44.7 17.8 1.2e-07 32.3 0.3 7.4 8 0 0 8 8 7 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBZ25943.1 - 1.4e-08 34.9 0.0 0.17 12.2 0.0 5.2 3 2 3 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain Coatomer_WDAD PF04053.14 CBZ25943.1 - 9.4e-07 28.2 0.0 0.0026 16.9 0.0 4.3 3 1 1 4 4 4 1 Coatomer WD associated region Clathrin PF00637.20 CBZ25943.1 - 2e-05 24.5 1.9 0.028 14.3 0.0 3.7 2 1 2 4 4 4 2 Region in Clathrin and VPS DUF2802 PF10975.8 CBZ25943.1 - 0.011 15.8 0.1 0.11 12.6 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2802) Nic96 PF04097.14 CBZ25943.1 - 0.019 13.5 0.0 0.035 12.6 0.0 1.3 1 0 0 1 1 1 0 Nup93/Nic96 TPR_MalT PF17874.1 CBZ25943.1 - 0.024 14.0 0.2 0.075 12.4 0.2 1.8 1 0 0 1 1 1 0 MalT-like TPR region TPR_7 PF13176.6 CBZ25943.1 - 0.035 14.1 2.7 4.1 7.6 0.0 4.4 5 1 1 6 6 5 0 Tetratricopeptide repeat WD40_like PF17005.5 CBZ25943.1 - 0.1 11.9 1.1 6.2 6.0 0.1 3.0 3 1 0 3 3 3 0 WD40-like domain TPR_2 PF07719.17 CBZ25943.1 - 0.1 12.7 9.7 14 6.1 0.3 6.1 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_1 PF00515.28 CBZ25943.1 - 5.4 7.0 9.6 47 4.0 0.3 4.9 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.6 CBZ25943.1 - 9 7.4 15.2 29 5.8 0.6 6.0 5 1 1 6 6 6 0 Tetratricopeptide repeat LOH1CR12 PF10158.9 CBZ25944.1 - 0.019 15.0 1.0 0.047 13.7 1.0 1.6 1 0 0 1 1 1 0 Tumour suppressor protein YbjN PF10722.9 CBZ25944.1 - 0.025 14.7 0.0 0.063 13.3 0.0 1.7 1 0 0 1 1 1 0 Putative bacterial sensory transduction regulator CLAMP PF14769.6 CBZ25947.1 - 4.3e-30 104.1 1.1 8.4e-30 103.2 1.1 1.6 1 0 0 1 1 1 1 Flagellar C1a complex subunit C1a-32 DUF5061 PF16587.5 CBZ25947.1 - 0.072 13.2 0.0 0.14 12.3 0.0 1.4 1 0 0 1 1 1 0 17 kDa common-antigen outer membrane protein Ribonuclease_3 PF00636.26 CBZ25948.1 - 0.0092 16.6 0.0 0.032 14.8 0.0 2.0 1 1 0 1 1 1 1 Ribonuclease III domain WSD PF15613.6 CBZ25949.1 - 5.8e-09 36.3 0.5 4.7e-08 33.4 0.0 2.9 2 0 0 2 2 2 1 Williams-Beuren syndrome DDT (WSD), D-TOX E motif BUD22 PF09073.10 CBZ25949.1 - 0.00029 20.3 22.9 0.0053 16.2 4.8 2.6 2 1 0 2 2 2 2 BUD22 DDT PF02791.17 CBZ25949.1 - 0.002 18.4 0.5 0.0075 16.6 0.2 2.1 2 0 0 2 2 2 1 DDT domain Ribosomal_L24e PF01246.20 CBZ25950.1 - 4.9e-21 74.7 1.1 4.9e-21 74.7 1.1 1.7 2 0 0 2 2 2 1 Ribosomal protein L24e DUF4189 PF13827.6 CBZ25952.1 - 0.026 15.0 1.3 0.038 14.5 0.7 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4189) Ribosomal_L24e PF01246.20 CBZ25953.1 - 4.9e-21 74.7 1.1 4.9e-21 74.7 1.1 1.7 2 0 0 2 2 2 1 Ribosomal protein L24e HORMA PF02301.18 CBZ25954.1 - 3.5e-50 170.5 0.0 4.5e-50 170.2 0.0 1.1 1 0 0 1 1 1 1 HORMA domain IL22 PF14565.6 CBZ25956.1 - 0.13 12.6 0.0 6.8 6.9 0.0 2.2 2 0 0 2 2 2 0 Interleukin 22 IL-10-related T-cell-derived-inducible factor 3HCDH_N PF02737.18 CBZ25957.1 - 3.1e-57 193.4 1.4 3.9e-57 193.1 1.4 1.1 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.22 CBZ25957.1 - 6.7e-34 116.4 0.0 1.8e-33 115.1 0.0 1.7 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain NAD_binding_2 PF03446.15 CBZ25957.1 - 0.013 15.7 1.3 0.21 11.7 1.3 2.1 1 1 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Pyr_redox_2 PF07992.14 CBZ25957.1 - 0.06 12.6 0.1 0.085 12.1 0.1 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_Gly3P_dh_N PF01210.23 CBZ25957.1 - 0.12 12.4 0.7 0.23 11.4 0.7 1.5 1 1 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Pyr_redox PF00070.27 CBZ25957.1 - 0.13 12.9 0.0 0.3 11.7 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase MTS PF05175.14 CBZ25957.1 - 0.13 11.8 0.1 0.26 10.8 0.1 1.4 1 0 0 1 1 1 0 Methyltransferase small domain Memo PF01875.17 CBZ25959.1 - 2.5e-60 203.9 0.0 3.4e-60 203.5 0.0 1.1 1 0 0 1 1 1 1 Memo-like protein CorA PF01544.18 CBZ25960.1 - 8.2e-05 22.1 0.2 0.00027 20.3 0.2 1.8 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein DUF4942 PF13708.6 CBZ25961.1 - 0.18 11.8 0.0 0.33 10.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4942) COQ7 PF03232.13 CBZ25962.1 - 0.046 13.5 0.1 0.06 13.1 0.1 1.2 1 0 0 1 1 1 0 Ubiquinone biosynthesis protein COQ7 Glyco_transf_22 PF03901.17 CBZ25963.1 - 1.4e-69 235.3 25.5 1.8e-69 235.0 25.5 1.1 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family PP2C PF00481.21 CBZ25966.1 - 3.3e-08 33.5 0.0 5.9e-08 32.7 0.0 1.4 1 0 0 1 1 1 1 Protein phosphatase 2C Agenet PF05641.12 CBZ25966.1 - 0.054 14.0 0.0 0.12 12.8 0.0 1.5 1 0 0 1 1 1 0 Agenet domain DUF5393 PF17371.2 CBZ25967.1 - 0 1099.9 14.5 0 1099.6 14.5 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF5393) S4 PF01479.25 CBZ25968.1 - 2.5e-13 49.5 0.3 5.7e-13 48.3 0.3 1.6 1 0 0 1 1 1 1 S4 domain Ribosomal_S4 PF00163.19 CBZ25968.1 - 1e-07 32.7 0.2 2.6e-07 31.4 0.2 1.8 1 1 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain TyrRSs_C PF16714.5 CBZ25968.1 - 0.02 14.7 0.0 0.029 14.2 0.0 1.3 1 0 0 1 1 1 0 Tyrosyl-tRNA synthetase C-terminal domain Glycolytic PF00274.19 CBZ25969.1 - 5.6e-143 475.9 0.0 6.3e-143 475.7 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-I Amastin PF07344.11 CBZ25971.1 - 6.2e-52 175.5 12.1 7.7e-52 175.2 12.1 1.1 1 0 0 1 1 1 1 Amastin surface glycoprotein SPC12 PF06645.13 CBZ25971.1 - 0.016 15.3 0.2 0.016 15.3 0.2 3.2 2 1 1 3 3 3 0 Microsomal signal peptidase 12 kDa subunit (SPC12) FGFR3_TM PF18123.1 CBZ25971.1 - 0.18 11.4 0.4 0.18 11.4 0.4 3.1 4 0 0 4 4 4 0 Fibroblast growth factor receptor 3 transmembrane domain DUF5302 PF17227.2 CBZ25972.1 - 0.03 15.3 2.2 0.06 14.4 0.2 2.4 2 0 0 2 2 2 0 Family of unknown function (DUF5302) VGLL4 PF15245.6 CBZ25972.1 - 0.05 13.7 2.3 0.054 13.6 0.8 1.8 1 1 1 2 2 2 0 Transcription cofactor vestigial-like protein 4 DUF3094 PF11293.8 CBZ25972.1 - 0.068 12.9 0.8 0.73 9.6 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3094) KfrA_N PF11740.8 CBZ25972.1 - 0.28 11.9 6.6 2.2 9.0 1.2 2.5 1 1 1 2 2 2 0 Plasmid replication region DNA-binding N-term SIP1 PF04938.12 CBZ25973.1 - 1.3e-05 25.0 0.0 3.6e-05 23.6 0.0 2.0 1 1 0 1 1 1 1 Survival motor neuron (SMN) interacting protein 1 (SIP1) BILBO1_N PF18281.1 CBZ25974.1 - 3.5e-28 97.9 0.6 6.7e-28 97.0 0.1 1.7 2 0 0 2 2 2 1 BILBO1 N-terminal domain GAS PF13851.6 CBZ25974.1 - 1.9 7.8 10.2 2.8 7.2 10.2 1.2 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding DUF1682 PF07946.14 CBZ25974.1 - 4.6 6.4 8.8 58 2.7 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1682) APG6_N PF17675.1 CBZ25974.1 - 4.7 7.7 18.8 17 5.9 17.8 2.0 1 1 1 2 2 2 0 Apg6 coiled-coil region Harakiri PF15196.6 CBZ25975.1 - 4.3 7.9 10.1 1.6 9.2 0.9 3.7 3 1 1 4 4 4 0 Activator of apoptosis harakiri DnaJ PF00226.31 CBZ25976.1 - 3.3e-07 30.3 0.0 7.7e-07 29.2 0.0 1.6 1 1 0 1 1 1 1 DnaJ domain NARP1 PF12569.8 CBZ25977.1 - 2.8e-85 287.2 16.9 1.3e-81 275.1 11.2 2.7 3 0 0 3 3 3 2 NMDA receptor-regulated protein 1 TPR_2 PF07719.17 CBZ25977.1 - 3.2e-13 48.7 16.1 0.00023 21.0 0.0 8.1 8 0 0 8 8 7 3 Tetratricopeptide repeat TPR_1 PF00515.28 CBZ25977.1 - 3.6e-11 42.4 7.7 9.5e-05 22.1 0.0 6.7 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_8 PF13181.6 CBZ25977.1 - 7.6e-09 35.1 3.8 0.017 15.3 0.0 5.8 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_17 PF13431.6 CBZ25977.1 - 2e-08 34.0 1.3 0.41 11.1 0.0 5.6 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_19 PF14559.6 CBZ25977.1 - 2.6e-08 34.2 5.8 0.0025 18.3 0.0 4.5 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.6 CBZ25977.1 - 4.1e-07 30.3 25.4 0.37 11.7 0.1 8.2 7 2 2 9 9 9 3 Tetratricopeptide repeat TPR_9 PF13371.6 CBZ25977.1 - 5.1e-06 26.5 9.1 0.00055 20.0 0.0 5.4 5 1 1 6 6 6 1 Tetratricopeptide repeat TPR_11 PF13414.6 CBZ25977.1 - 6e-06 25.8 1.7 0.055 13.2 0.0 5.3 4 1 1 5 5 5 1 TPR repeat TPR_12 PF13424.6 CBZ25977.1 - 0.00061 20.0 17.5 0.2 12.0 0.0 6.0 6 2 0 6 6 6 2 Tetratricopeptide repeat TPR_7 PF13176.6 CBZ25977.1 - 0.0011 18.8 8.2 11 6.3 0.0 6.5 6 1 1 7 7 6 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 CBZ25977.1 - 0.0051 16.9 1.1 21 5.3 0.0 4.5 4 0 0 4 4 4 0 Fis1 C-terminal tetratricopeptide repeat TPR_16 PF13432.6 CBZ25977.1 - 0.0058 17.3 24.2 0.9 10.2 4.3 6.9 6 2 3 9 9 9 3 Tetratricopeptide repeat TPR_10 PF13374.6 CBZ25977.1 - 0.027 14.3 1.4 4.8 7.2 0.1 4.0 3 0 0 3 3 3 0 Tetratricopeptide repeat ANAPC3 PF12895.7 CBZ25977.1 - 0.061 13.6 16.9 0.65 10.3 0.0 5.5 4 1 1 5 5 5 0 Anaphase-promoting complex, cyclosome, subunit 3 DUF1771 PF08590.10 CBZ25977.1 - 0.96 9.9 8.0 1.8 9.0 3.8 3.0 1 1 1 2 2 2 0 Domain of unknown function (DUF1771) zf-PARP PF00645.18 CBZ25978.1 - 8.5e-18 65.0 2.2 9.9e-18 64.8 1.1 1.7 2 0 0 2 2 2 1 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region zf-CCHH PF10283.9 CBZ25978.1 - 2.9e-10 39.9 4.9 5e-10 39.2 4.9 1.3 1 0 0 1 1 1 1 PBZ domain ADK PF00406.22 CBZ25979.1 - 2.1e-42 144.8 0.0 3.3e-42 144.1 0.0 1.3 1 1 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 CBZ25979.1 - 2.1e-25 89.7 0.0 7e-25 88.0 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 CBZ25979.1 - 1.6e-12 48.1 0.0 1.5e-11 45.0 0.0 2.1 2 1 0 2 2 2 1 AAA domain AAA_33 PF13671.6 CBZ25979.1 - 1.8e-05 25.0 0.8 0.00033 20.8 0.8 2.7 1 1 0 1 1 1 1 AAA domain Hydin_ADK PF17213.3 CBZ25979.1 - 0.0012 19.1 0.1 0.03 14.6 0.0 2.5 2 1 1 3 3 3 1 Hydin Adenylate kinase-like domain Cytidylate_kin PF02224.18 CBZ25979.1 - 0.0016 18.2 0.0 0.0082 15.9 0.0 2.0 1 1 0 2 2 2 1 Cytidylate kinase AAA PF00004.29 CBZ25979.1 - 0.0057 17.1 0.0 0.015 15.7 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Thymidylate_kin PF02223.17 CBZ25979.1 - 0.012 15.2 0.2 1.8 8.2 0.0 2.9 3 0 0 3 3 3 0 Thymidylate kinase dNK PF01712.19 CBZ25979.1 - 0.015 15.2 0.4 5.5 6.8 0.0 2.7 3 0 0 3 3 3 0 Deoxynucleoside kinase AAA_24 PF13479.6 CBZ25979.1 - 0.032 13.9 0.2 7.4 6.2 0.0 2.3 2 0 0 2 2 2 0 AAA domain RuvB_N PF05496.12 CBZ25979.1 - 0.048 13.4 0.0 0.084 12.6 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain Zeta_toxin PF06414.12 CBZ25979.1 - 0.053 12.8 0.0 0.24 10.6 0.0 1.9 2 1 0 2 2 2 0 Zeta toxin ABC_tran PF00005.27 CBZ25979.1 - 0.11 13.0 0.2 3.9 8.0 0.0 2.2 2 0 0 2 2 2 0 ABC transporter Rad17 PF03215.15 CBZ25979.1 - 0.11 12.4 0.1 0.65 9.9 0.0 2.2 2 1 0 2 2 2 0 Rad17 P-loop domain RNA_pol_Rpb2_7 PF04560.20 CBZ25979.1 - 0.15 12.5 0.1 0.33 11.4 0.1 1.5 1 0 0 1 1 1 0 RNA polymerase Rpb2, domain 7 AAA PF00004.29 CBZ25980.1 - 7.4e-96 317.6 0.0 6e-47 159.4 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 CBZ25980.1 - 9.4e-27 92.6 8.4 2.1e-13 49.8 0.3 3.1 3 1 0 3 3 2 2 AAA+ lid domain CDC48_N PF02359.18 CBZ25980.1 - 6.4e-21 74.3 0.3 2.8e-20 72.3 0.1 2.3 2 0 0 2 2 1 1 Cell division protein 48 (CDC48), N-terminal domain RuvB_N PF05496.12 CBZ25980.1 - 1e-13 51.3 0.0 1e-05 25.3 0.0 2.7 2 2 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 CBZ25980.1 - 2.1e-12 47.7 0.2 0.00044 20.7 0.0 4.0 2 2 1 3 3 3 2 AAA ATPase domain AAA_2 PF07724.14 CBZ25980.1 - 3.8e-12 46.7 0.0 2.3e-06 27.8 0.0 2.7 2 1 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_33 PF13671.6 CBZ25980.1 - 3.5e-11 43.4 0.0 1.1e-05 25.6 0.0 2.6 2 0 0 2 2 2 2 AAA domain CDC48_2 PF02933.17 CBZ25980.1 - 2e-10 40.3 0.0 4.6e-10 39.1 0.0 1.7 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), domain 2 AAA_5 PF07728.14 CBZ25980.1 - 2.2e-10 40.7 0.1 6.7e-05 22.9 0.0 3.5 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 CBZ25980.1 - 2.9e-09 37.3 0.4 0.037 14.3 0.0 3.9 2 2 2 4 4 4 2 AAA domain TIP49 PF06068.13 CBZ25980.1 - 9.6e-09 34.9 0.1 0.00037 19.8 0.1 2.5 2 0 0 2 2 2 2 TIP49 P-loop domain AAA_18 PF13238.6 CBZ25980.1 - 1.5e-07 32.1 0.0 0.015 15.8 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_14 PF13173.6 CBZ25980.1 - 1.5e-07 31.5 0.0 0.0047 17.0 0.0 2.4 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.22 CBZ25980.1 - 2e-07 31.4 0.0 0.0049 17.2 0.0 2.9 2 0 0 2 2 2 2 RNA helicase Mg_chelatase PF01078.21 CBZ25980.1 - 4.6e-07 29.4 0.2 0.031 13.7 0.0 2.5 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 CBZ25980.1 - 4.4e-06 26.5 0.0 0.075 12.8 0.0 2.5 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_17 PF13207.6 CBZ25980.1 - 1.5e-05 25.4 0.0 0.11 12.9 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.6 CBZ25980.1 - 1.5e-05 24.6 0.3 1.1 8.9 0.0 3.5 2 1 1 3 3 3 1 AAA domain Vps4_C PF09336.10 CBZ25980.1 - 1.7e-05 24.7 0.1 0.00056 19.9 0.0 2.7 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain ABC_tran PF00005.27 CBZ25980.1 - 1.7e-05 25.3 0.0 0.054 14.0 0.0 3.0 2 1 0 2 2 2 1 ABC transporter Zeta_toxin PF06414.12 CBZ25980.1 - 1.9e-05 24.0 0.0 0.11 11.8 0.0 2.5 2 0 0 2 2 2 2 Zeta toxin AAA_28 PF13521.6 CBZ25980.1 - 2e-05 24.9 0.0 0.24 11.6 0.0 2.8 3 0 0 3 3 2 2 AAA domain ATPase_2 PF01637.18 CBZ25980.1 - 2.5e-05 24.3 0.2 0.33 10.8 0.1 3.0 2 1 0 2 2 2 2 ATPase domain predominantly from Archaea Bac_DnaA PF00308.18 CBZ25980.1 - 3.1e-05 23.9 0.0 0.039 13.8 0.0 2.4 2 0 0 2 2 2 1 Bacterial dnaA protein Parvo_NS1 PF01057.17 CBZ25980.1 - 3.7e-05 23.0 0.0 0.056 12.5 0.0 2.2 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 ATPase PF06745.13 CBZ25980.1 - 4.7e-05 22.8 0.2 1.5 8.1 0.0 3.6 3 0 0 3 3 3 1 KaiC NACHT PF05729.12 CBZ25980.1 - 5.7e-05 23.1 0.1 0.19 11.6 0.0 3.2 3 1 0 3 3 3 1 NACHT domain AAA_24 PF13479.6 CBZ25980.1 - 5.9e-05 22.9 0.0 0.11 12.2 0.0 2.5 2 0 0 2 2 2 2 AAA domain Sigma54_activat PF00158.26 CBZ25980.1 - 0.00011 22.0 0.0 0.68 9.6 0.0 3.2 2 1 0 2 2 2 2 Sigma-54 interaction domain TsaE PF02367.17 CBZ25980.1 - 0.00011 22.2 0.0 0.64 10.0 0.0 2.6 3 0 0 3 3 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE Viral_helicase1 PF01443.18 CBZ25980.1 - 0.00013 21.8 0.0 0.016 15.0 0.0 2.3 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase AAA_7 PF12775.7 CBZ25980.1 - 0.00016 21.2 0.0 0.49 9.9 0.0 2.8 2 1 0 2 2 2 2 P-loop containing dynein motor region AAA_3 PF07726.11 CBZ25980.1 - 0.00034 20.5 0.0 0.96 9.3 0.0 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) ResIII PF04851.15 CBZ25980.1 - 0.00073 19.6 0.0 0.066 13.2 0.0 2.3 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit NB-ARC PF00931.22 CBZ25980.1 - 0.00074 18.8 0.0 0.98 8.6 0.0 2.4 2 0 0 2 2 2 2 NB-ARC domain Sigma54_activ_2 PF14532.6 CBZ25980.1 - 0.0011 19.1 0.0 0.65 10.1 0.0 2.6 2 0 0 2 2 2 1 Sigma-54 interaction domain PhoH PF02562.16 CBZ25980.1 - 0.0025 17.3 0.1 1.4 8.3 0.0 2.4 2 0 0 2 2 2 1 PhoH-like protein DUF2075 PF09848.9 CBZ25980.1 - 0.0031 16.8 0.0 0.87 8.8 0.0 2.3 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) NTPase_1 PF03266.15 CBZ25980.1 - 0.008 16.1 0.9 10 6.0 0.0 3.9 3 1 1 4 4 4 0 NTPase Rad17 PF03215.15 CBZ25980.1 - 0.0093 15.9 0.0 1.9 8.4 0.0 2.6 2 0 0 2 2 2 1 Rad17 P-loop domain Molydop_binding PF01568.21 CBZ25980.1 - 0.015 15.3 0.0 0.034 14.2 0.0 1.5 1 0 0 1 1 1 0 Molydopterin dinucleotide binding domain Cytidylate_kin2 PF13189.6 CBZ25980.1 - 0.018 15.2 0.4 1.3 9.2 0.0 2.7 3 0 0 3 3 2 0 Cytidylate kinase-like family DUF815 PF05673.13 CBZ25980.1 - 0.023 13.9 0.0 5.7 6.0 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF815) Cytidylate_kin PF02224.18 CBZ25980.1 - 0.033 13.9 0.0 5.5 6.7 0.0 2.6 2 0 0 2 2 2 0 Cytidylate kinase AAA_11 PF13086.6 CBZ25980.1 - 0.043 13.6 0.0 12 5.6 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 CBZ25980.1 - 0.045 13.5 0.0 7.3 6.4 0.0 2.7 2 0 0 2 2 2 0 P-loop containing region of AAA domain DEAD PF00270.29 CBZ25980.1 - 0.056 13.2 0.2 7.3 6.3 0.0 3.4 4 0 0 4 4 4 0 DEAD/DEAH box helicase SKI PF01202.22 CBZ25980.1 - 0.058 13.5 0.1 18 5.5 0.0 2.5 2 0 0 2 2 2 0 Shikimate kinase AAA_23 PF13476.6 CBZ25980.1 - 0.072 13.6 0.1 24 5.4 0.0 2.7 2 1 0 2 2 2 0 AAA domain KAP_NTPase PF07693.14 CBZ25980.1 - 0.073 12.3 0.1 3.3 6.8 0.0 3.0 2 2 1 4 4 4 0 KAP family P-loop domain AAA_19 PF13245.6 CBZ25980.1 - 0.087 13.2 3.3 9.6 6.5 0.1 3.3 3 1 0 4 4 2 0 AAA domain AAA_30 PF13604.6 CBZ25980.1 - 0.091 12.5 0.1 9.5 5.9 0.0 2.5 2 0 0 2 2 2 0 AAA domain Zot PF05707.12 CBZ25980.1 - 0.093 12.4 0.0 1.1 8.8 0.0 2.6 2 1 0 2 2 2 0 Zonular occludens toxin (Zot) CPT PF07931.12 CBZ25980.1 - 0.1 12.4 0.0 3.7 7.4 0.0 2.6 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein TEX19 PF15553.6 CBZ25980.1 - 0.16 11.9 0.1 0.3 11.0 0.1 1.4 1 0 0 1 1 1 0 Testis-expressed protein 19 AFG1_ATPase PF03969.16 CBZ25980.1 - 0.24 10.2 1.5 11 4.8 0.0 2.7 3 0 0 3 3 3 0 AFG1-like ATPase Trypsin_2 PF13365.6 CBZ25981.1 - 4.6e-06 27.6 0.1 6.9e-06 27.0 0.1 1.3 1 0 0 1 1 1 1 Trypsin-like peptidase domain DUF755 PF05501.11 CBZ25982.1 - 0.013 15.8 5.2 0.038 14.2 5.2 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF755) APG6_N PF17675.1 CBZ25982.1 - 1.5 9.3 8.5 6.5 7.3 8.5 2.2 1 0 0 1 1 1 0 Apg6 coiled-coil region ARL2_Bind_BART PF11527.8 CBZ25984.1 - 1.5e-32 112.1 1.5 3.3e-32 111.0 1.5 1.6 1 0 0 1 1 1 1 The ARF-like 2 binding protein BART UIM PF02809.20 CBZ25984.1 - 0.0028 17.5 0.3 0.0028 17.5 0.3 4.1 4 0 0 4 4 4 1 Ubiquitin interaction motif Musclin PF11037.8 CBZ25984.1 - 0.077 12.9 0.3 0.21 11.5 0.3 1.7 1 0 0 1 1 1 0 Insulin-resistance promoting peptide in skeletal muscle Wbp11 PF09429.10 CBZ25984.1 - 0.19 12.1 0.0 0.19 12.1 0.0 2.9 3 0 0 3 3 3 0 WW domain binding protein 11 zf-RanBP PF00641.18 CBZ25986.1 - 1.2e-16 59.7 83.3 1e-08 34.4 2.9 9.3 9 0 0 9 9 9 7 Zn-finger in Ran binding protein and others DZR PF12773.7 CBZ25986.1 - 0.00034 20.6 69.7 0.0017 18.3 6.5 7.0 4 3 1 5 5 5 4 Double zinc ribbon EF1_GNE PF00736.19 CBZ25987.1 - 3.7e-26 91.1 0.7 6e-26 90.5 0.7 1.3 1 0 0 1 1 1 1 EF-1 guanine nucleotide exchange domain DUF3752 PF12572.8 CBZ25987.1 - 0.0043 17.6 0.6 0.0059 17.1 0.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3752) Glyco_hydro_2_C PF02836.17 CBZ25987.1 - 0.075 12.1 0.1 1.9 7.5 0.1 2.0 2 0 0 2 2 2 0 Glycosyl hydrolases family 2, TIM barrel domain THOC2_N PF16134.5 CBZ25987.1 - 0.62 8.6 5.1 0.76 8.3 5.1 1.1 1 0 0 1 1 1 0 THO complex subunit 2 N-terminus Chorein_N PF12624.7 CBZ25988.1 - 4.4e-25 88.0 0.2 1.8e-11 44.2 0.1 2.6 2 0 0 2 2 2 2 N-terminal region of Chorein or VPS13 VPS13_C PF16909.5 CBZ25988.1 - 1.5e-15 57.4 0.1 3.6e-09 36.6 0.0 2.4 2 0 0 2 2 2 2 Vacuolar-sorting-associated 13 protein C-terminal VPS13 PF16908.5 CBZ25988.1 - 1e-06 28.8 2.0 4.9e-06 26.5 2.0 2.2 1 1 0 1 1 1 1 Vacuolar sorting-associated protein 13, N-terminal TAF4 PF05236.14 CBZ25988.1 - 0.34 10.6 1.2 0.8 9.4 0.1 2.1 2 0 0 2 2 2 0 Transcription initiation factor TFIID component TAF4 family DUF5582 PF17819.1 CBZ25989.1 - 0.00029 21.3 0.2 0.00058 20.3 0.2 1.4 1 0 0 1 1 1 1 Family of unknown function (DUF5582) RuBisCO_large PF00016.20 CBZ25989.1 - 0.02 14.1 0.0 0.025 13.8 0.0 1.1 1 0 0 1 1 1 0 Ribulose bisphosphate carboxylase large chain, catalytic domain EF-hand_7 PF13499.6 CBZ25989.1 - 0.027 14.9 0.0 0.55 10.7 0.0 2.0 1 1 1 2 2 2 0 EF-hand domain pair Kelch_4 PF13418.6 CBZ25991.1 - 6.4e-20 70.9 0.1 3e-08 33.5 0.0 5.1 5 0 0 5 5 5 3 Galactose oxidase, central domain Kelch_1 PF01344.25 CBZ25991.1 - 2.7e-17 62.1 1.8 2e-07 30.5 0.0 4.3 4 0 0 4 4 4 2 Kelch motif Kelch_3 PF13415.6 CBZ25991.1 - 1e-12 48.0 0.1 0.00015 22.0 0.0 4.9 5 0 0 5 5 5 2 Galactose oxidase, central domain Kelch_6 PF13964.6 CBZ25991.1 - 1.1e-09 38.2 0.9 0.00032 20.9 0.0 4.6 5 0 0 5 5 5 2 Kelch motif Kelch_2 PF07646.15 CBZ25991.1 - 1.2e-09 37.8 0.3 9.3e-06 25.4 0.0 4.2 4 0 0 4 4 4 2 Kelch motif Kelch_5 PF13854.6 CBZ25991.1 - 2e-09 37.2 1.8 0.0007 19.5 0.0 4.2 3 0 0 3 3 3 2 Kelch motif DUF648 PF04890.13 CBZ25992.1 - 0.19 11.5 0.0 0.28 10.9 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF648) DUF4090 PF13319.6 CBZ25994.1 - 0.16 12.3 0.0 0.41 10.9 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF4090) DUF4795 PF16043.5 CBZ25995.1 - 0.013 15.1 0.4 0.016 14.8 0.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4795) Spectrin PF00435.21 CBZ25995.1 - 0.11 13.0 3.8 0.14 12.7 0.6 2.4 1 1 1 2 2 2 0 Spectrin repeat zf-C2HCIx2C PF10782.9 CBZ25995.1 - 0.24 11.3 0.0 0.24 11.3 0.0 2.2 3 0 0 3 3 3 0 Zinc-finger Allexi_40kDa PF05549.11 CBZ25995.1 - 0.36 10.3 1.9 0.79 9.2 0.1 1.9 2 0 0 2 2 2 0 Allexivirus 40kDa protein Pkinase PF00069.25 CBZ25996.1 - 5.4e-56 189.9 0.0 8.3e-56 189.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ25996.1 - 5.9e-35 120.8 0.0 9.5e-35 120.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CBZ25996.1 - 6e-06 25.8 0.0 1.5e-05 24.5 0.0 1.6 1 1 0 1 1 1 1 Kinase-like PH PF00169.29 CBZ25996.1 - 0.00016 22.2 0.3 0.00057 20.4 0.3 1.9 1 1 0 1 1 1 1 PH domain PH_11 PF15413.6 CBZ25996.1 - 0.00057 20.3 0.0 0.0012 19.2 0.0 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain PH_9 PF15410.6 CBZ25996.1 - 0.028 14.8 0.1 0.11 12.9 0.1 2.0 2 1 0 2 2 2 0 Pleckstrin homology domain PH_4 PF15404.6 CBZ25996.1 - 0.042 13.6 0.0 0.089 12.6 0.0 1.5 1 0 0 1 1 1 0 Pleckstrin homology domain Pkinase_fungal PF17667.1 CBZ25996.1 - 0.13 11.0 0.0 0.22 10.3 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Pkinase PF00069.25 CBZ25997.1 - 1.2e-54 185.4 0.0 1.6e-54 185.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ25997.1 - 2.2e-35 122.2 0.0 3.1e-35 121.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CBZ25997.1 - 4.9e-08 32.6 0.0 9.5e-08 31.7 0.0 1.4 1 0 0 1 1 1 1 Kinase-like PH PF00169.29 CBZ25997.1 - 4e-06 27.3 0.0 9e-06 26.2 0.0 1.6 1 0 0 1 1 1 1 PH domain Pkinase_fungal PF17667.1 CBZ25997.1 - 0.0013 17.6 0.0 0.0021 16.9 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase ELMO_CED12 PF04727.13 CBZ25998.1 - 2.4e-32 112.5 0.0 3.5e-32 111.9 0.0 1.3 1 0 0 1 1 1 1 ELMO/CED-12 family zf-B_box PF00643.24 CBZ25999.1 - 1.4e-07 31.6 7.5 1.4e-07 31.6 7.5 4.0 5 0 0 5 5 5 2 B-box zinc finger LRR_4 PF12799.7 CBZ26000.1 - 2.1e-18 66.1 9.4 0.0022 18.4 1.2 5.6 4 1 1 5 5 5 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CBZ26000.1 - 1.9e-15 56.4 9.0 6.8e-07 29.0 0.2 5.0 4 1 0 4 4 4 3 Leucine rich repeat LRR_9 PF14580.6 CBZ26000.1 - 1.2e-08 34.6 3.5 0.0017 17.9 0.7 3.4 2 1 2 4 4 4 2 Leucine-rich repeat LRR_6 PF13516.6 CBZ26000.1 - 0.0075 16.2 8.4 13 6.2 0.0 5.7 5 0 0 5 5 5 1 Leucine Rich repeat LRR_5 PF13306.6 CBZ26000.1 - 0.21 11.6 0.0 0.38 10.7 0.0 1.3 1 0 0 1 1 1 0 BspA type Leucine rich repeat region (6 copies) LRR_1 PF00560.33 CBZ26000.1 - 2.2 9.2 16.4 31 5.7 1.3 6.9 6 2 0 6 6 6 0 Leucine Rich Repeat DUF4407 PF14362.6 CBZ26001.1 - 0.00015 21.3 22.8 0.00093 18.6 15.0 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF4407) DUF2408 PF10303.9 CBZ26001.1 - 6.1 7.4 15.2 1.2 9.7 4.4 3.3 2 1 0 3 3 3 0 Protein of unknown function (DUF2408) FAM184 PF15665.5 CBZ26001.1 - 9.8 5.9 32.6 0.26 11.1 0.5 2.9 2 1 0 2 2 2 0 Family with sequence similarity 184, A and B STAG PF08514.11 CBZ26003.1 - 1.9e-21 76.1 0.6 1.9e-21 76.1 0.6 2.7 2 0 0 2 2 2 1 STAG domain CCDC24 PF15669.5 CBZ26003.1 - 0.21 11.5 4.5 1.6 8.5 0.0 3.7 5 1 0 5 5 5 0 Coiled-coil domain-containing protein 24 family Proteasome PF00227.26 CBZ26005.1 - 3e-55 186.7 0.1 3.8e-55 186.3 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 CBZ26005.1 - 2.7e-13 49.3 0.0 7.3e-13 47.9 0.0 1.8 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature zf-CCHC PF00098.23 CBZ26006.1 - 2.1e-42 141.3 41.2 1.1e-09 37.9 1.9 5.1 5 0 0 5 5 5 5 Zinc knuckle zf-CCHC_3 PF13917.6 CBZ26006.1 - 1.5e-13 50.4 29.1 0.0066 16.4 1.4 5.0 1 1 4 5 5 5 5 Zinc knuckle zf-CCHC_4 PF14392.6 CBZ26006.1 - 1.6e-08 34.1 28.4 0.14 11.9 1.4 5.0 5 0 0 5 5 5 5 Zinc knuckle zf-CCHC_6 PF15288.6 CBZ26006.1 - 1.1e-05 25.2 28.8 0.019 14.8 1.7 5.1 2 2 3 5 5 5 3 Zinc knuckle zf-CCHC_2 PF13696.6 CBZ26006.1 - 0.0041 16.9 30.8 0.054 13.3 0.9 5.3 5 0 0 5 5 5 3 Zinc knuckle HscB_4_cys PF18256.1 CBZ26006.1 - 0.048 13.5 25.4 8.5 6.3 1.4 5.5 5 0 0 5 5 5 0 Co-chaperone HscB tetracysteine metal binding motif TRAF6_Z2 PF18048.1 CBZ26006.1 - 0.12 12.4 12.6 19 5.5 0.1 5.4 5 1 0 5 5 5 0 TNF receptor-associated factor 6 zinc finger 2 zf-CCHC_5 PF14787.6 CBZ26006.1 - 0.13 12.0 30.5 1.9 8.2 0.5 5.1 5 0 0 5 5 5 0 GAG-polyprotein viral zinc-finger Dermcidin PF15291.6 CBZ26006.1 - 0.14 12.8 0.5 1.3 9.6 0.1 2.1 1 1 1 2 2 2 0 Dermcidin, antibiotic peptide zf-CCHC PF00098.23 CBZ26007.1 - 3.2e-41 137.6 42.6 1.5e-09 37.4 3.1 5.4 5 0 0 5 5 5 5 Zinc knuckle zf-CCHC_3 PF13917.6 CBZ26007.1 - 2.4e-12 46.6 29.4 0.013 15.5 1.6 5.2 1 1 4 5 5 5 5 Zinc knuckle zf-CCHC_4 PF14392.6 CBZ26007.1 - 2.3e-07 30.5 28.7 0.18 11.6 1.0 5.2 5 0 0 5 5 5 5 Zinc knuckle zf-CCHC_6 PF15288.6 CBZ26007.1 - 3.6e-05 23.5 29.2 0.037 13.9 1.7 5.4 2 2 3 5 5 5 3 Zinc knuckle TRAF6_Z2 PF18048.1 CBZ26007.1 - 0.25 11.5 12.5 34 4.7 0.1 5.3 5 0 0 5 5 5 0 TNF receptor-associated factor 6 zinc finger 2 HscB_4_cys PF18256.1 CBZ26007.1 - 1.1 9.1 26.4 15 5.5 1.4 5.6 5 0 0 5 5 5 0 Co-chaperone HscB tetracysteine metal binding motif zf-ribbon_3 PF13248.6 CBZ26007.1 - 2.4 7.7 23.0 12 5.5 0.1 6.0 5 0 0 5 5 5 0 zinc-ribbon domain Clathrin PF00637.20 CBZ26008.1 - 1e-162 534.5 38.3 1.8e-27 96.0 1.1 8.5 9 0 0 9 9 9 7 Region in Clathrin and VPS Clathrin_H_link PF13838.6 CBZ26008.1 - 1.5e-17 63.3 0.0 7.8e-17 61.0 0.0 2.4 1 0 0 1 1 1 1 Clathrin-H-link Clathrin_propel PF01394.20 CBZ26008.1 - 1e-09 38.2 1.2 0.12 12.8 0.0 4.8 5 0 0 5 5 5 3 Clathrin propeller repeat Clathrin-link PF09268.10 CBZ26008.1 - 6.6e-07 28.6 0.0 2.4e-06 26.8 0.0 2.1 1 0 0 1 1 1 1 Clathrin, heavy-chain linker TPR_1 PF00515.28 CBZ26008.1 - 0.0091 15.8 0.2 8.8 6.3 0.1 4.9 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_7 PF13176.6 CBZ26008.1 - 0.024 14.7 4.6 29 5.0 0.0 7.0 8 0 0 8 8 8 0 Tetratricopeptide repeat Mic1 PF07035.12 CBZ26008.1 - 0.027 14.2 6.7 0.26 11.0 0.0 4.4 3 1 0 4 4 4 0 Colon cancer-associated protein Mic1-like Egg_lysin PF01303.17 CBZ26008.1 - 0.11 12.8 4.9 1.4 9.2 0.6 3.5 3 0 0 3 3 3 0 Egg lysin (Sperm-lysin) Dynein_heavy PF03028.15 CBZ26008.1 - 0.2 11.8 0.8 2.1 8.4 0.3 3.0 2 0 0 2 2 2 0 Dynein heavy chain region D6 P-loop domain PDDEXK_10 PF07788.11 CBZ26008.1 - 0.21 11.5 3.6 1.6 8.7 0.0 3.6 3 0 0 3 3 3 0 PD-(D/E)XK nuclease superfamily zf-CCHC PF00098.23 CBZ26009.1 - 3.7e-39 131.1 50.0 2.4e-07 30.5 1.9 6.1 6 0 0 6 6 6 6 Zinc knuckle zf-CCHC_2 PF13696.6 CBZ26009.1 - 4.4e-09 36.0 50.5 6.5e-05 22.7 2.4 6.3 6 0 0 6 6 6 5 Zinc knuckle zf-CCHC_3 PF13917.6 CBZ26009.1 - 1.4e-08 34.5 31.6 0.017 15.1 0.9 5.0 3 2 2 5 5 5 4 Zinc knuckle zf-CCHC_4 PF14392.6 CBZ26009.1 - 6.3e-07 29.0 31.3 0.12 12.1 1.6 6.0 6 0 0 6 6 6 5 Zinc knuckle zf-CCHC_5 PF14787.6 CBZ26009.1 - 1.4e-05 24.7 40.0 0.0021 17.7 0.8 5.6 4 2 2 6 6 6 5 GAG-polyprotein viral zinc-finger zf-CCHC PF00098.23 CBZ26010.1 - 1.9e-83 271.1 98.5 1.2e-08 34.6 1.9 10.2 10 0 0 10 10 10 10 Zinc knuckle zf-CCHC_3 PF13917.6 CBZ26010.1 - 1.6e-28 98.4 62.0 0.0029 17.6 0.4 10.1 3 3 7 10 10 10 10 Zinc knuckle zf-CCHC_5 PF14787.6 CBZ26010.1 - 1.3e-08 34.4 71.8 0.39 10.5 1.0 10.2 10 0 0 10 10 10 10 GAG-polyprotein viral zinc-finger zf-CCHC_2 PF13696.6 CBZ26010.1 - 2.7e-08 33.5 75.3 0.0004 20.1 1.9 10.5 10 0 0 10 10 10 5 Zinc knuckle zf-CCHC_4 PF14392.6 CBZ26010.1 - 3.6e-08 33.0 59.5 1.1 9.0 0.5 10.1 10 0 0 10 10 10 10 Zinc knuckle TRAF6_Z2 PF18048.1 CBZ26010.1 - 0.0022 18.1 33.6 28 4.9 0.0 9.8 10 0 0 10 10 10 0 TNF receptor-associated factor 6 zinc finger 2 zf-CCHC_6 PF15288.6 CBZ26010.1 - 0.043 13.7 78.5 1 9.3 0.9 10.2 9 1 1 10 10 10 0 Zinc knuckle Ntox16 PF15523.6 CBZ26010.1 - 0.35 11.1 50.6 3.7 7.9 0.5 9.2 8 1 0 9 9 9 0 Novel toxin 16 Proteasome PF00227.26 CBZ26011.1 - 5.5e-48 163.0 0.2 6.7e-48 162.7 0.2 1.1 1 0 0 1 1 1 1 Proteasome subunit PseudoU_synth_2 PF00849.22 CBZ26012.1 - 2.3e-06 27.8 0.0 3.9e-06 27.0 0.0 1.4 1 0 0 1 1 1 1 RNA pseudouridylate synthase S4 PF01479.25 CBZ26012.1 - 2.8e-06 26.9 0.0 2e-05 24.2 0.0 2.3 2 0 0 2 2 2 1 S4 domain Q_salvage PF10343.9 CBZ26013.1 - 8.3e-18 65.0 0.0 7.3e-16 58.6 0.0 2.7 3 0 0 3 3 3 2 Potential Queuosine, Q, salvage protein family Ank PF00023.30 CBZ26013.1 - 0.065 13.7 0.0 0.21 12.1 0.0 2.0 1 0 0 1 1 1 0 Ankyrin repeat Peptidase_M76 PF09768.9 CBZ26015.1 - 2.1e-56 190.3 0.0 3.3e-56 189.7 0.0 1.3 1 1 0 1 1 1 1 Peptidase M76 family HTH_30 PF13556.6 CBZ26015.1 - 0.01 15.6 0.0 0.023 14.5 0.0 1.5 1 0 0 1 1 1 0 PucR C-terminal helix-turn-helix domain GPI2 PF06432.11 CBZ26017.1 - 5.6e-67 226.1 13.9 6.6e-67 225.9 13.9 1.1 1 0 0 1 1 1 1 Phosphatidylinositol N-acetylglucosaminyltransferase Sprouty PF05210.13 CBZ26017.1 - 0.038 14.4 0.2 0.11 12.9 0.2 1.8 1 0 0 1 1 1 0 Sprouty protein (Spry) Beach PF02138.18 CBZ26018.1 - 7.5e-108 360.1 0.0 1.1e-107 359.6 0.0 1.2 1 0 0 1 1 1 1 Beige/BEACH domain PH_BEACH PF14844.6 CBZ26018.1 - 3.5e-22 78.4 0.0 6.8e-22 77.5 0.0 1.5 1 0 0 1 1 1 1 PH domain associated with Beige/BEACH Laminin_G_3 PF13385.6 CBZ26018.1 - 3.6e-05 24.0 0.0 7.8e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily Sec34 PF04136.15 CBZ26019.1 - 6e-12 45.7 0.9 6e-12 45.7 0.9 2.0 2 0 0 2 2 2 1 Sec34-like family GAF PF01590.26 CBZ26020.1 - 0.2 12.3 1.8 33 5.1 0.1 4.0 3 1 0 3 3 3 0 GAF domain Aldedh PF00171.22 CBZ26022.1 - 6.9e-164 545.7 0.2 7.8e-164 545.6 0.2 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF3253 PF11625.8 CBZ26022.1 - 0.017 15.3 0.2 0.047 13.9 0.2 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3253) DUF1487 PF07368.11 CBZ26022.1 - 0.13 11.7 0.0 0.22 11.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1487) TPR_2 PF07719.17 CBZ26024.1 - 2.4e-19 67.8 12.1 0.00013 21.8 0.1 9.1 10 0 0 10 10 10 4 Tetratricopeptide repeat TPR_1 PF00515.28 CBZ26024.1 - 1.7e-16 59.2 8.8 5.6e-05 22.8 0.0 8.1 9 0 0 9 9 9 3 Tetratricopeptide repeat TPR_9 PF13371.6 CBZ26024.1 - 4.6e-11 42.7 16.4 4e-07 30.1 0.4 5.1 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_19 PF14559.6 CBZ26024.1 - 6.9e-11 42.5 18.7 0.051 14.1 0.1 7.3 5 2 3 8 8 8 4 Tetratricopeptide repeat TPR_11 PF13414.6 CBZ26024.1 - 4.7e-10 39.0 4.5 0.28 10.9 0.1 6.3 5 1 1 6 6 6 3 TPR repeat TPR_16 PF13432.6 CBZ26024.1 - 2.8e-08 34.2 14.9 0.0022 18.6 0.1 6.8 5 2 2 7 7 6 3 Tetratricopeptide repeat TPR_8 PF13181.6 CBZ26024.1 - 3.9e-08 32.9 0.5 6.1 7.3 0.0 7.1 5 1 2 7 7 7 1 Tetratricopeptide repeat TPR_12 PF13424.6 CBZ26024.1 - 6.6e-07 29.5 15.3 0.16 12.3 0.2 6.3 5 2 3 8 8 8 2 Tetratricopeptide repeat TPR_7 PF13176.6 CBZ26024.1 - 1e-06 28.3 16.7 0.026 14.5 0.2 7.0 6 1 0 6 6 6 3 Tetratricopeptide repeat TPR_14 PF13428.6 CBZ26024.1 - 2.5e-06 27.8 28.2 5.2 8.2 0.9 9.5 6 3 5 11 11 10 2 Tetratricopeptide repeat TPR_17 PF13431.6 CBZ26024.1 - 2.9e-06 27.3 3.6 1.2 9.7 0.0 5.3 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_15 PF13429.6 CBZ26024.1 - 0.011 15.0 3.3 0.44 9.7 0.0 4.0 4 1 0 5 5 5 0 Tetratricopeptide repeat TPR_20 PF14561.6 CBZ26024.1 - 0.033 14.5 0.3 0.39 11.1 0.0 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat ANAPC3 PF12895.7 CBZ26024.1 - 0.045 14.0 11.4 1.9 8.8 0.1 5.3 4 1 1 5 5 5 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_21 PF09976.9 CBZ26024.1 - 0.15 11.8 0.0 10 5.8 0.0 2.8 1 1 1 2 2 2 0 Tetratricopeptide repeat-like domain Miga PF10265.9 CBZ26024.1 - 0.25 10.3 1.0 20 4.0 0.0 2.7 3 0 0 3 3 3 0 Mitoguardin TPR_10 PF13374.6 CBZ26024.1 - 0.51 10.3 17.8 5.3 7.0 0.7 6.7 8 0 0 8 8 8 0 Tetratricopeptide repeat TPR_4 PF07721.14 CBZ26024.1 - 6.3 7.7 7.8 12 6.8 0.2 4.6 4 0 0 4 4 3 0 Tetratricopeptide repeat XRN_N PF03159.18 CBZ26025.1 - 3.1e-85 285.5 1.7 4.2e-85 285.1 0.0 1.9 2 0 0 2 2 2 1 XRN 5'-3' exonuclease N-terminus XRN_M PF17846.1 CBZ26025.1 - 7.8e-63 212.9 3.5 7.8e-63 212.9 3.5 2.9 2 1 0 2 2 2 1 Xrn1 helical domain DUF3678 PF12435.8 CBZ26026.1 - 5.1 6.6 6.2 13 5.2 0.6 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3678) MORN PF02493.20 CBZ26027.1 - 2.9e-55 181.0 86.5 5.4e-07 29.1 0.6 18.8 20 0 0 20 20 20 15 MORN repeat DUF3048_C PF17479.2 CBZ26027.1 - 0.14 12.6 7.6 0.65 10.4 0.1 4.3 5 1 0 5 5 5 0 Protein of unknown function (DUF3048) C-terminal domain Ras PF00071.22 CBZ26028.1 - 4.7e-14 52.3 0.0 7.4e-14 51.7 0.0 1.3 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CBZ26028.1 - 7.2e-09 35.9 0.0 1.6e-08 34.8 0.0 1.6 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase AAA_16 PF13191.6 CBZ26028.1 - 0.017 15.5 0.0 0.039 14.3 0.0 1.7 1 1 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 CBZ26028.1 - 0.028 14.7 0.0 0.068 13.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 CBZ26028.1 - 0.081 13.0 0.0 0.18 11.9 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase Arf PF00025.21 CBZ26028.1 - 0.23 10.9 0.0 0.44 10.0 0.0 1.3 1 0 0 1 1 1 0 ADP-ribosylation factor family GET2 PF08690.10 CBZ26028.1 - 5.3 6.6 8.6 0.22 11.1 2.2 1.9 2 0 0 2 2 2 0 GET complex subunit GET2 SprA-related PF12118.8 CBZ26029.1 - 0.0031 16.7 3.6 0.0045 16.2 2.4 1.9 2 0 0 2 2 2 1 SprA-related family DEAD PF00270.29 CBZ26030.1 - 1.2e-42 145.7 0.0 2.6e-42 144.6 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CBZ26030.1 - 2.3e-23 82.7 0.0 1.9e-22 79.7 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 CBZ26030.1 - 2.6e-14 53.2 0.0 5.4e-14 52.2 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) DEAD PF00270.29 CBZ26031.1 - 8.8e-46 155.9 0.1 3.1e-45 154.1 0.1 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CBZ26031.1 - 5e-28 97.7 0.1 5.7e-27 94.3 0.0 2.7 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 CBZ26031.1 - 2.8e-05 24.2 0.0 9.8e-05 22.4 0.0 1.9 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 CBZ26031.1 - 0.00029 20.1 0.1 0.00084 18.6 0.0 1.6 1 1 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase SNF2_N PF00176.23 CBZ26031.1 - 0.019 13.7 0.0 0.029 13.1 0.0 1.3 1 0 0 1 1 1 0 SNF2 family N-terminal domain Ribosomal_S5_C PF03719.15 CBZ26032.1 - 5.8e-11 41.7 0.1 9.6e-11 41.0 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain Ribosomal_S5 PF00333.20 CBZ26032.1 - 2.3e-06 27.5 0.0 4.5e-06 26.6 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S5, N-terminal domain DUF1918 PF08940.11 CBZ26032.1 - 0.14 11.8 0.0 0.65 9.7 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF1918) MVP_shoulder PF11978.8 CBZ26033.1 - 1.5e-45 154.0 0.0 2.5e-45 153.3 0.0 1.4 1 0 0 1 1 1 1 Shoulder domain Vault PF01505.18 CBZ26033.1 - 2.6e-29 101.1 0.0 5.6e-12 45.6 0.0 5.1 4 0 0 4 4 4 4 Major Vault Protein repeat domain Vault_2 PF17794.1 CBZ26033.1 - 4.4e-19 68.6 0.4 3e-12 46.7 0.1 3.5 3 1 0 3 3 3 2 Major Vault Protein repeat domain Vault_3 PF17795.1 CBZ26033.1 - 1.3e-15 57.2 0.0 9.4e-15 54.4 0.0 2.6 1 1 0 1 1 1 1 Major Vault Protein Repeat domain Vault_4 PF17796.1 CBZ26033.1 - 1.9e-12 47.0 0.0 9.1e-12 44.9 0.0 2.2 1 0 0 1 1 1 1 Major Vault Protein repeat domain Tfb4 PF03850.14 CBZ26033.1 - 0.14 11.6 3.3 0.25 10.8 3.3 1.3 1 0 0 1 1 1 0 Transcription factor Tfb4 CBF PF03914.17 CBZ26034.1 - 2.2e-29 102.7 0.3 2.2e-29 102.7 0.3 2.5 2 1 0 2 2 2 1 CBF/Mak21 family NOC3p PF07540.11 CBZ26034.1 - 1.4e-05 25.4 0.1 1.4e-05 25.4 0.1 2.1 2 0 0 2 2 2 1 Nucleolar complex-associated protein CENP-H PF05837.12 CBZ26034.1 - 0.039 14.4 4.3 0.63 10.5 1.9 2.9 2 0 0 2 2 2 0 Centromere protein H (CENP-H) DASH_Dad3 PF08656.10 CBZ26034.1 - 0.25 11.5 1.8 0.91 9.6 0.1 2.7 3 0 0 3 3 3 0 DASH complex subunit Dad3 ETRAMP PF09716.10 CBZ26034.1 - 0.3 11.2 1.1 0.74 9.9 1.1 1.6 1 0 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) GAS PF13851.6 CBZ26038.1 - 1.2e-54 184.7 27.6 1.2e-54 184.7 27.6 3.9 3 1 1 4 4 4 1 Growth-arrest specific micro-tubule binding Filament PF00038.21 CBZ26038.1 - 4.5 6.8 66.1 1.1 8.8 7.1 4.4 1 1 2 3 3 3 0 Intermediate filament protein MCU PF04678.13 CBZ26039.1 - 0.06 13.4 7.5 1.3 9.1 7.5 2.9 1 1 0 1 1 1 0 Mitochondrial calcium uniporter Baculo_PEP_C PF04513.12 CBZ26039.1 - 0.23 11.5 1.1 7.1 6.7 0.0 3.3 3 1 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus CorA PF01544.18 CBZ26039.1 - 7.2 5.8 12.7 0.34 10.2 2.7 3.2 3 1 1 4 4 4 0 CorA-like Mg2+ transporter protein Ribosomal_L37ae PF01780.19 CBZ26040.1 - 9.2e-37 125.0 4.5 1e-36 124.9 4.5 1.0 1 0 0 1 1 1 1 Ribosomal L37ae protein family C1_1 PF00130.22 CBZ26040.1 - 0.0022 17.8 2.3 0.0032 17.3 2.3 1.2 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-RING_13 PF17977.1 CBZ26040.1 - 0.05 13.7 1.1 0.071 13.2 1.1 1.2 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Zn_Tnp_IS1595 PF12760.7 CBZ26040.1 - 0.065 13.2 2.3 0.11 12.5 2.3 1.4 1 0 0 1 1 1 0 Transposase zinc-ribbon domain NOB1_Zn_bind PF08772.11 CBZ26040.1 - 0.16 12.2 3.8 0.43 10.8 0.6 2.3 1 1 1 2 2 2 0 Nin one binding (NOB1) Zn-ribbon like zf-C3HC4 PF00097.25 CBZ26041.1 - 1.3e-10 41.0 5.9 2e-10 40.4 5.9 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 CBZ26041.1 - 3.8e-10 39.5 3.5 5.3e-10 39.0 3.5 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CBZ26041.1 - 3.2e-09 36.7 3.0 3.2e-09 36.7 3.0 2.0 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 CBZ26041.1 - 4.3e-09 36.1 8.2 6.7e-09 35.4 8.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CBZ26041.1 - 8.5e-09 35.6 9.1 1.3e-08 35.0 9.1 1.3 1 0 0 1 1 1 1 Ring finger domain Prok-RING_4 PF14447.6 CBZ26041.1 - 1e-08 34.9 5.5 1.7e-08 34.2 5.5 1.3 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 CBZ26041.1 - 4.3e-07 29.8 5.7 6.7e-07 29.2 5.7 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 CBZ26041.1 - 5.2e-07 29.7 6.9 8.7e-07 29.0 6.9 1.4 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.7 CBZ26041.1 - 0.00019 21.7 7.4 0.00047 20.4 7.4 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 CBZ26041.1 - 0.0033 17.4 2.1 0.006 16.6 2.1 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Baculo_IE-1 PF05290.11 CBZ26041.1 - 0.0086 16.0 1.9 0.014 15.4 1.9 1.2 1 0 0 1 1 1 1 Baculovirus immediate-early protein (IE-0) zf-RING_6 PF14835.6 CBZ26041.1 - 0.02 14.8 4.2 0.047 13.6 4.2 1.5 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-RING_10 PF16685.5 CBZ26041.1 - 0.14 12.3 3.3 0.24 11.6 3.3 1.3 1 0 0 1 1 1 0 zinc RING finger of MSL2 zf-RING_4 PF14570.6 CBZ26041.1 - 0.16 11.8 5.0 0.41 10.5 5.0 1.6 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain Pex14_N PF04695.13 CBZ26041.1 - 0.34 11.6 12.0 20 5.8 10.4 2.7 2 1 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region RINGv PF12906.7 CBZ26041.1 - 0.47 10.6 4.5 1.4 9.1 4.5 1.8 1 1 0 1 1 1 0 RING-variant domain Zn_ribbon_17 PF17120.5 CBZ26041.1 - 0.6 9.8 6.6 1 9.1 6.6 1.3 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type IBR PF01485.21 CBZ26041.1 - 2 8.7 8.5 1.4 9.2 6.6 1.7 1 1 0 1 1 1 0 IBR domain, a half RING-finger domain zf-RING_11 PF17123.5 CBZ26041.1 - 3.5 7.4 7.5 1.3 8.9 4.1 2.1 2 0 0 2 2 2 0 RING-like zinc finger Nucleoside_tran PF01733.18 CBZ26042.1 - 2.3e-26 92.9 7.3 2.3e-26 92.9 7.3 2.2 2 1 0 2 2 2 1 Nucleoside transporter Ndc1_Nup PF09531.10 CBZ26042.1 - 0.35 9.5 4.1 0.12 11.0 0.5 1.9 2 0 0 2 2 2 0 Nucleoporin protein Ndc1-Nup MutS_V PF00488.21 CBZ26043.1 - 4.3e-55 186.7 0.4 6.9e-54 182.7 0.4 2.6 1 1 0 1 1 1 1 MutS domain V MutS_I PF01624.20 CBZ26043.1 - 5.2e-33 113.6 0.1 1.3e-32 112.4 0.1 1.7 1 0 0 1 1 1 1 MutS domain I MutS_III PF05192.18 CBZ26043.1 - 1.9e-32 113.1 0.5 3.9e-32 112.0 0.5 1.6 1 0 0 1 1 1 1 MutS domain III AAA_29 PF13555.6 CBZ26043.1 - 0.0012 18.5 0.4 0.035 13.9 0.0 2.7 2 0 0 2 2 2 1 P-loop containing region of AAA domain ABC_tran PF00005.27 CBZ26043.1 - 0.0032 18.0 0.0 0.0095 16.5 0.0 1.8 1 0 0 1 1 1 1 ABC transporter AAA_27 PF13514.6 CBZ26043.1 - 0.084 12.4 0.0 0.29 10.7 0.0 1.9 1 0 0 1 1 1 0 AAA domain DUF4976 PF16347.5 CBZ26043.1 - 0.29 11.4 0.9 0.68 10.2 0.9 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4976) TLD PF07534.16 CBZ26044.1 - 3.8e-21 75.8 0.1 4.4e-20 72.3 0.1 2.1 1 1 0 1 1 1 1 TLD DUF4487 PF14868.6 CBZ26044.1 - 0.24 10.2 0.8 0.35 9.7 0.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4487) PMM PF03332.13 CBZ26045.1 - 1.7e-100 335.3 0.8 1.9e-100 335.2 0.8 1.0 1 0 0 1 1 1 1 Eukaryotic phosphomannomutase Hydrolase_3 PF08282.12 CBZ26045.1 - 3.9e-08 33.3 0.0 9.9e-08 32.0 0.0 1.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase S6PP PF05116.13 CBZ26045.1 - 7.4e-06 25.7 0.0 0.025 14.1 0.0 2.1 2 0 0 2 2 2 2 Sucrose-6F-phosphate phosphohydrolase FliG_N PF14842.6 CBZ26045.1 - 0.089 13.3 0.0 0.19 12.3 0.0 1.5 1 0 0 1 1 1 0 FliG N-terminal domain Hydrolase PF00702.26 CBZ26045.1 - 0.12 12.6 0.1 0.2 11.9 0.1 1.6 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 CBZ26045.1 - 0.34 11.0 2.6 8.9 6.4 0.0 3.2 2 2 1 4 4 4 0 Haloacid dehalogenase-like hydrolase 2OG-FeII_Oxy_2 PF13532.6 CBZ26046.1 - 6.3e-07 29.8 0.0 1.1e-06 29.0 0.0 1.5 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.20 CBZ26046.1 - 0.008 16.7 0.0 0.018 15.5 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Metallophos PF00149.28 CBZ26047.1 - 2.2e-17 64.2 0.0 3e-17 63.8 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase YL1 PF05764.13 CBZ26049.1 - 0.18 11.9 1.5 0.33 11.1 1.5 1.3 1 0 0 1 1 1 0 YL1 nuclear protein Peptidase_A4 PF01828.17 CBZ26050.1 - 0.012 15.1 0.1 0.019 14.4 0.1 1.4 1 0 0 1 1 1 0 Peptidase A4 family FlxA PF14282.6 CBZ26050.1 - 0.017 15.1 6.2 0.017 15.1 6.2 2.6 2 1 0 2 2 2 0 FlxA-like protein tRNA_U5-meth_tr PF05958.11 CBZ26050.1 - 0.25 10.3 7.2 0.5 9.3 7.2 1.5 1 1 0 1 1 1 0 tRNA (Uracil-5-)-methyltransferase CAMSAP_CC1 PF17095.5 CBZ26050.1 - 0.47 10.4 6.4 0.72 9.7 0.3 2.9 3 0 0 3 3 3 0 Spectrin-binding region of Ca2+-Calmodulin TPR_MLP1_2 PF07926.12 CBZ26050.1 - 1.9 8.6 37.4 0.74 9.9 8.3 2.6 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein Cpn60_TCP1 PF00118.24 CBZ26051.1 - 9.4e-86 288.4 16.0 1.4e-85 287.8 16.0 1.2 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Cpn60_TCP1 PF00118.24 CBZ26052.1 - 6.5e-86 288.9 16.0 1.4e-85 287.8 16.0 1.4 1 1 0 1 1 1 1 TCP-1/cpn60 chaperonin family Ribosomal_L12 PF00542.19 CBZ26052.1 - 0.15 12.4 2.2 1.5 9.2 0.1 3.1 2 0 0 2 2 2 0 Ribosomal protein L7/L12 C-terminal domain WD40 PF00400.32 CBZ26053.1 - 1.5e-08 35.1 7.6 0.027 15.3 0.5 5.5 5 0 0 5 5 5 4 WD domain, G-beta repeat ALG3 PF05208.13 CBZ26054.1 - 8.2e-124 413.6 14.1 9.8e-124 413.4 14.1 1.0 1 0 0 1 1 1 1 ALG3 protein DUF3146 PF11344.8 CBZ26054.1 - 0.21 11.3 1.0 0.66 9.7 0.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3146) Metallophos PF00149.28 CBZ26055.1 - 4e-14 53.6 0.0 7.9e-10 39.6 0.0 2.9 2 1 0 2 2 2 2 Calcineurin-like phosphoesterase DUF72 PF01904.18 CBZ26056.1 - 5e-29 102.0 0.0 4.9e-27 95.5 0.0 2.1 2 0 0 2 2 2 2 Protein of unknown function DUF72 TPR_2 PF07719.17 CBZ26057.1 - 6.5e-12 44.6 9.1 8.2e-07 28.7 0.7 4.0 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.28 CBZ26057.1 - 3.3e-10 39.3 7.0 2.6e-05 23.9 0.1 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_8 PF13181.6 CBZ26057.1 - 3.2e-06 26.9 0.8 0.00027 20.9 0.0 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.6 CBZ26057.1 - 4.7e-06 26.2 1.8 0.022 14.5 0.7 3.6 2 2 1 3 3 3 3 TPR repeat TPR_16 PF13432.6 CBZ26057.1 - 2.5e-05 24.8 3.8 2.5e-05 24.8 3.8 4.1 5 2 0 5 5 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 CBZ26057.1 - 0.00017 22.1 4.0 0.00017 22.1 4.0 3.7 4 1 1 5 5 4 1 Tetratricopeptide repeat TPR_12 PF13424.6 CBZ26057.1 - 0.00026 21.2 5.6 0.012 15.9 1.1 3.0 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.6 CBZ26057.1 - 0.0023 17.8 3.0 0.021 14.8 0.3 3.4 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_10 PF13374.6 CBZ26057.1 - 0.056 13.3 0.5 0.056 13.3 0.5 2.9 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_19 PF14559.6 CBZ26057.1 - 0.057 13.9 4.5 0.17 12.4 2.9 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_9 PF13371.6 CBZ26057.1 - 0.073 13.2 6.9 1.7 8.8 3.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat T2SSppdC PF12528.8 CBZ26057.1 - 0.081 13.7 0.3 0.23 12.2 0.3 1.8 1 0 0 1 1 1 0 Type II secretion prepilin peptidase dependent protein C SPA PF08616.10 CBZ26059.1 - 4e-05 23.5 0.0 0.0001 22.2 0.0 1.6 1 0 0 1 1 1 1 Stabilization of polarity axis Avl9 PF09794.9 CBZ26059.1 - 0.0047 15.7 0.0 0.0084 14.8 0.0 1.4 1 0 0 1 1 1 1 Transport protein Avl9 DENN PF02141.21 CBZ26059.1 - 0.11 12.4 3.4 5.1 7.0 0.2 2.8 1 1 0 2 2 2 0 DENN (AEX-3) domain Acetyltransf_10 PF13673.7 CBZ26060.1 - 0.0001 22.2 0.0 0.0015 18.4 0.0 2.2 1 1 1 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 CBZ26060.1 - 0.0015 18.8 0.0 0.0099 16.1 0.0 2.2 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family DnaJ PF00226.31 CBZ26061.1 - 3.3e-22 78.4 0.5 5e-22 77.8 0.5 1.3 1 0 0 1 1 1 1 DnaJ domain DUF1977 PF09320.11 CBZ26061.1 - 6.3e-07 29.6 1.4 3.4e-06 27.3 0.1 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF1977) DEAD PF00270.29 CBZ26064.1 - 1.3e-48 165.1 0.0 2.6e-48 164.1 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CBZ26064.1 - 2.8e-31 108.1 0.0 1e-29 103.1 0.1 2.5 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 CBZ26064.1 - 6.1e-05 23.1 0.0 0.0024 17.9 0.0 2.3 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_30 PF13604.6 CBZ26064.1 - 0.00081 19.2 0.0 0.067 12.9 0.0 2.6 2 1 0 2 2 2 1 AAA domain ERCC3_RAD25_C PF16203.5 CBZ26064.1 - 0.0017 17.6 0.1 0.0025 17.1 0.1 1.2 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase DUF2239 PF09998.9 CBZ26064.1 - 0.042 13.6 0.1 1 9.1 0.1 2.2 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2239) EMP24_GP25L PF01105.24 CBZ26066.1 - 7.5e-26 91.2 0.0 1.1e-25 90.7 0.0 1.2 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Dynein_light PF01221.18 CBZ26067.1 - 2.8e-21 75.6 0.0 3.5e-21 75.3 0.0 1.1 1 0 0 1 1 1 1 Dynein light chain type 1 DUF3646 PF12362.8 CBZ26067.1 - 0.058 13.7 0.0 0.09 13.1 0.0 1.4 1 1 0 1 1 1 0 DNA polymerase III gamma and tau subunits C terminal Alpha-amyl_C PF09071.10 CBZ26067.1 - 0.093 12.6 0.0 0.16 11.9 0.0 1.4 1 0 0 1 1 1 0 Alpha-amylase, C terminal Methyltr_RsmB-F PF01189.17 CBZ26068.1 - 5.9e-31 107.7 0.0 2e-23 83.1 0.0 2.9 2 1 0 2 2 2 2 16S rRNA methyltransferase RsmB/F FtsJ PF01728.19 CBZ26068.1 - 0.00083 19.5 0.0 0.0028 17.8 0.0 1.8 1 0 0 1 1 1 1 FtsJ-like methyltransferase DREPP PF05558.12 CBZ26068.1 - 0.092 12.6 4.6 0.17 11.8 4.6 1.3 1 0 0 1 1 1 0 DREPP plasma membrane polypeptide Methyltransf_31 PF13847.6 CBZ26068.1 - 0.12 12.1 0.0 0.29 10.9 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Y_phosphatase PF00102.27 CBZ26069.1 - 4.2e-43 147.6 0.0 1e-42 146.3 0.0 1.7 1 1 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.20 CBZ26069.1 - 7.6e-05 22.5 0.0 0.00017 21.4 0.0 1.5 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Sld7_C PF18596.1 CBZ26070.1 - 0.32 11.2 3.0 2.8 8.1 0.5 2.9 3 0 0 3 3 3 0 Sld7 C-terminal domain Choline_transpo PF04515.12 CBZ26072.1 - 2.8e-65 220.7 35.4 2.8e-65 220.7 35.4 2.6 2 1 0 2 2 2 1 Plasma-membrane choline transporter BRCT_2 PF16589.5 CBZ26073.1 - 2.4e-06 27.8 0.0 0.0092 16.4 0.0 2.4 2 0 0 2 2 2 2 BRCT domain, a BRCA1 C-terminus domain BRCT_3 PF18428.1 CBZ26073.1 - 0.00043 20.3 0.1 0.071 13.2 0.0 2.3 2 0 0 2 2 2 2 BRCA1 C Terminus (BRCT) domain BRCT PF00533.26 CBZ26073.1 - 0.0085 16.5 0.0 0.32 11.4 0.0 2.9 2 2 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.7 CBZ26073.1 - 0.039 13.9 0.0 6.6 6.8 0.0 2.8 3 0 0 3 3 3 0 twin BRCT domain Sec1 PF00995.23 CBZ26074.1 - 2e-100 337.7 0.0 2.4e-100 337.5 0.0 1.0 1 0 0 1 1 1 1 Sec1 family Corona_NSP4_C PF16348.5 CBZ26074.1 - 0.17 12.7 1.6 12 6.8 0.0 3.4 2 2 1 3 3 3 0 Coronavirus nonstructural protein 4 C-terminus GCP_N_terminal PF17681.1 CBZ26075.1 - 6.5e-15 55.6 0.0 3.2e-14 53.3 0.0 2.1 2 0 0 2 2 2 1 Gamma tubulin complex component N-terminal MMR_HSR1_Xtn PF16897.5 CBZ26076.1 - 1.5e-41 140.7 0.0 3.2e-41 139.6 0.0 1.5 1 0 0 1 1 1 1 C-terminal region of MMR_HSR1 domain MMR_HSR1 PF01926.23 CBZ26076.1 - 1.3e-19 70.4 0.0 2.9e-19 69.2 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase TGS PF02824.21 CBZ26076.1 - 2.3e-19 69.2 0.0 4.4e-19 68.3 0.0 1.5 1 0 0 1 1 1 1 TGS domain FeoB_N PF02421.18 CBZ26076.1 - 3.6e-09 36.3 0.0 1.3e-08 34.5 0.0 1.8 2 0 0 2 2 2 1 Ferrous iron transport protein B MeaB PF03308.16 CBZ26076.1 - 0.0029 16.6 0.1 0.0096 14.9 0.1 1.8 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB Dynamin_N PF00350.23 CBZ26076.1 - 0.058 13.5 0.2 2.5 8.1 0.0 2.4 1 1 1 2 2 2 0 Dynamin family Guanylate_kin PF00625.21 CBZ26077.1 - 3e-40 137.9 0.0 3.1e-23 82.4 0.0 3.0 2 1 0 2 2 2 2 Guanylate kinase AAA_33 PF13671.6 CBZ26077.1 - 1.1e-05 25.6 0.5 0.00031 20.9 0.5 2.3 1 1 0 1 1 1 1 AAA domain Rad17 PF03215.15 CBZ26077.1 - 7e-05 22.8 0.0 0.00017 21.6 0.0 1.6 2 0 0 2 2 2 1 Rad17 P-loop domain AAA_16 PF13191.6 CBZ26077.1 - 0.00019 21.8 0.0 0.00034 21.0 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain MMR_HSR1 PF01926.23 CBZ26077.1 - 0.0041 17.2 0.0 0.0087 16.1 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 CBZ26077.1 - 0.0043 17.0 0.0 0.0072 16.2 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase AAA_22 PF13401.6 CBZ26077.1 - 0.0044 17.3 0.0 0.0086 16.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 CBZ26077.1 - 0.005 17.2 0.0 0.043 14.2 0.0 2.2 2 0 0 2 2 2 1 RNA helicase ABC_tran PF00005.27 CBZ26077.1 - 0.0078 16.7 0.0 0.021 15.4 0.0 1.6 1 0 0 1 1 1 1 ABC transporter AAA_18 PF13238.6 CBZ26077.1 - 0.014 16.0 0.0 0.13 12.8 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 CBZ26077.1 - 0.014 15.6 0.0 0.061 13.6 0.0 2.2 2 1 0 2 2 2 0 AAA domain AAA_29 PF13555.6 CBZ26077.1 - 0.021 14.6 0.0 0.041 13.6 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain dNK PF01712.19 CBZ26077.1 - 0.021 14.7 0.1 1.7 8.4 0.1 2.2 2 0 0 2 2 2 0 Deoxynucleoside kinase AAA_7 PF12775.7 CBZ26077.1 - 0.028 13.9 0.0 0.052 13.1 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA PF00004.29 CBZ26077.1 - 0.03 14.7 0.0 0.057 13.8 0.0 1.7 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) TniB PF05621.11 CBZ26077.1 - 0.036 13.5 0.0 0.062 12.7 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein AAA_5 PF07728.14 CBZ26077.1 - 0.042 13.9 0.0 0.11 12.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) RNA_pol_N PF01194.17 CBZ26077.1 - 0.043 14.1 0.0 0.1 12.9 0.0 1.6 1 0 0 1 1 1 0 RNA polymerases N / 8 kDa subunit NACHT PF05729.12 CBZ26077.1 - 0.057 13.3 0.0 0.16 11.9 0.0 1.7 2 0 0 2 2 2 0 NACHT domain Mg_chelatase PF01078.21 CBZ26077.1 - 0.061 12.7 0.0 0.1 12.0 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Viral_helicase1 PF01443.18 CBZ26077.1 - 0.091 12.5 0.0 0.19 11.5 0.0 1.5 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_17 PF13207.6 CBZ26077.1 - 0.14 12.6 0.0 1.9 8.9 0.0 2.2 2 0 0 2 2 2 0 AAA domain TPR_1 PF00515.28 CBZ26079.1 - 1.8e-34 116.1 1.1 0.00041 20.1 0.0 8.3 8 0 0 8 8 8 7 Tetratricopeptide repeat TPR_2 PF07719.17 CBZ26079.1 - 1e-31 106.4 6.3 0.0017 18.3 0.2 9.5 10 0 0 10 10 9 6 Tetratricopeptide repeat TPR_8 PF13181.6 CBZ26079.1 - 9.4e-24 81.6 0.1 0.00036 20.5 0.0 8.1 9 0 0 9 9 8 4 Tetratricopeptide repeat TPR_11 PF13414.6 CBZ26079.1 - 1.1e-23 82.7 0.6 4.7e-07 29.4 0.1 7.2 5 2 3 8 8 7 5 TPR repeat TPR_16 PF13432.6 CBZ26079.1 - 5.2e-20 71.8 8.5 0.0016 19.1 0.2 7.3 4 2 4 8 8 8 4 Tetratricopeptide repeat TPR_17 PF13431.6 CBZ26079.1 - 8.1e-20 69.7 1.8 0.00037 20.7 0.0 8.0 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_12 PF13424.6 CBZ26079.1 - 2.9e-17 62.7 17.1 6.1e-06 26.4 2.6 6.9 2 2 4 7 7 7 4 Tetratricopeptide repeat TPR_14 PF13428.6 CBZ26079.1 - 2.8e-16 58.8 11.2 0.0011 19.6 0.0 8.0 5 3 4 9 9 7 3 Tetratricopeptide repeat TPR_19 PF14559.6 CBZ26079.1 - 1.7e-15 57.3 4.4 1.6e-06 28.5 0.2 5.1 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_6 PF13174.6 CBZ26079.1 - 1.5e-13 50.5 5.2 2.1 9.2 0.1 8.3 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_9 PF13371.6 CBZ26079.1 - 3.8e-12 46.2 8.8 3.3e-06 27.1 0.1 5.1 3 1 2 6 6 6 4 Tetratricopeptide repeat ANAPC3 PF12895.7 CBZ26079.1 - 1.3e-11 44.5 12.9 0.00018 21.7 0.0 5.3 4 1 1 5 5 5 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.6 CBZ26079.1 - 6.1e-09 35.3 11.4 0.62 10.2 0.1 7.0 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_10 PF13374.6 CBZ26079.1 - 1.6e-07 31.0 9.2 0.0024 17.7 0.1 5.3 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_20 PF14561.6 CBZ26079.1 - 9.1e-06 25.9 0.1 1 9.7 0.1 4.5 4 1 1 5 5 4 2 Tetratricopeptide repeat TPR_4 PF07721.14 CBZ26079.1 - 0.00027 21.3 10.7 0.023 15.3 1.0 4.5 3 0 0 3 3 3 1 Tetratricopeptide repeat Paf67 PF10255.9 CBZ26079.1 - 0.0003 19.9 2.8 0.2 10.6 0.2 2.4 2 0 0 2 2 2 2 RNA polymerase I-associated factor PAF67 Wzy_C_2 PF11846.8 CBZ26079.1 - 0.00066 19.7 1.1 0.93 9.4 0.1 2.6 3 0 0 3 3 2 2 Virulence factor membrane-bound polymerase, C-terminal TPR_15 PF13429.6 CBZ26079.1 - 0.00093 18.5 5.8 2.8 7.1 0.0 4.5 1 1 0 4 4 4 1 Tetratricopeptide repeat PknG_TPR PF16918.5 CBZ26079.1 - 0.00096 18.0 0.2 0.009 14.8 0.0 2.4 3 0 0 3 3 3 1 Protein kinase G tetratricopeptide repeat ChAPs PF09295.10 CBZ26079.1 - 0.0017 17.5 1.1 0.42 9.6 0.0 3.0 2 1 1 3 3 3 1 ChAPs (Chs5p-Arf1p-binding proteins) Fis1_TPR_C PF14853.6 CBZ26079.1 - 0.019 15.0 4.0 10 6.3 0.1 5.5 6 1 0 6 6 6 0 Fis1 C-terminal tetratricopeptide repeat DUF3856 PF12968.7 CBZ26079.1 - 0.032 14.3 3.4 6.7 6.8 0.0 3.7 5 0 0 5 5 4 0 Domain of Unknown Function (DUF3856) GM_CSF PF01109.17 CBZ26079.1 - 0.044 14.0 0.0 2.2 8.5 0.1 2.5 2 0 0 2 2 2 0 Granulocyte-macrophage colony-stimulating factor BTAD PF03704.17 CBZ26079.1 - 0.061 13.8 7.7 0.16 12.4 1.6 3.5 3 2 0 3 3 3 0 Bacterial transcriptional activator domain DUF3808 PF10300.9 CBZ26079.1 - 0.077 11.7 0.1 0.11 11.2 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3808) HTH_Bact PF18768.1 CBZ26079.1 - 0.14 11.8 0.0 1.3 8.7 0.0 2.6 3 0 0 3 3 3 0 Helix-turn-helix bacterial domain Alkyl_sulf_dimr PF14863.6 CBZ26079.1 - 0.15 12.5 0.1 57 4.1 0.0 3.3 3 0 0 3 3 3 0 Alkyl sulfatase dimerisation NARP1 PF12569.8 CBZ26079.1 - 0.18 10.7 0.1 7.2 5.4 0.0 3.0 3 1 1 4 4 4 0 NMDA receptor-regulated protein 1 MIT PF04212.18 CBZ26079.1 - 0.31 11.2 7.5 16 5.7 0.3 5.8 6 1 1 7 7 7 0 MIT (microtubule interacting and transport) domain DUF5113 PF17140.4 CBZ26079.1 - 0.41 10.4 2.8 24 4.7 0.0 3.6 4 0 0 4 4 3 0 Domain of unknown function (DUF5113) ANAPC5 PF12862.7 CBZ26079.1 - 0.5 10.5 2.4 21 5.3 0.0 3.5 3 1 0 3 3 2 0 Anaphase-promoting complex subunit 5 Pkinase PF00069.25 CBZ26080.1 - 1.4e-50 172.1 0.0 1.6e-46 158.8 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ26080.1 - 1.6e-34 119.4 0.0 1.1e-33 116.7 0.0 1.9 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 CBZ26080.1 - 2.2e-06 27.2 0.0 3.3e-06 26.6 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 CBZ26080.1 - 0.00023 20.1 0.0 0.00033 19.5 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Seadorna_VP7 PF07387.11 CBZ26080.1 - 0.053 12.6 0.1 0.081 12.0 0.1 1.1 1 0 0 1 1 1 0 Seadornavirus VP7 Pox_ser-thr_kin PF05445.11 CBZ26080.1 - 0.11 11.5 0.0 0.37 9.7 0.0 1.7 2 0 0 2 2 2 0 Poxvirus serine/threonine protein kinase Ribosomal_S18 PF01084.20 CBZ26082.1 - 0.00015 21.9 0.0 0.00032 20.9 0.0 1.6 1 0 0 1 1 1 1 Ribosomal protein S18 Glucokinase PF02685.16 CBZ26083.1 - 1.8e-15 56.8 0.0 6.8e-15 54.9 0.0 1.8 1 1 0 1 1 1 1 Glucokinase Endonuclease_5 PF04493.14 CBZ26084.1 - 6.9e-52 176.0 0.0 9e-52 175.6 0.0 1.1 1 0 0 1 1 1 1 Endonuclease V adh_short PF00106.25 CBZ26085.1 - 9.7e-17 61.1 0.4 1e-08 34.9 0.0 2.7 2 1 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 CBZ26085.1 - 3e-08 33.5 0.1 9.3e-06 25.4 0.0 2.5 1 1 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CBZ26085.1 - 3.1e-05 23.9 1.6 9.4e-05 22.4 1.6 1.7 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 CBZ26085.1 - 0.035 13.6 0.0 0.055 12.9 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family TrkA_N PF02254.18 CBZ26085.1 - 0.04 14.2 0.0 0.079 13.2 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain Toxin_TOLIP PF00087.21 CBZ26085.1 - 0.042 14.1 1.4 0.13 12.5 1.0 2.0 2 0 0 2 2 2 0 Snake toxin and toxin-like protein NAD_binding_2 PF03446.15 CBZ26085.1 - 0.063 13.5 0.0 0.12 12.5 0.0 1.5 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Gp_dh_C PF02800.20 CBZ26086.1 - 1.5e-67 226.1 0.0 2.1e-67 225.7 0.0 1.2 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.24 CBZ26086.1 - 4.1e-40 136.2 0.2 8.5e-40 135.2 0.2 1.5 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain DapB_N PF01113.20 CBZ26086.1 - 0.00094 19.3 0.7 0.0056 16.8 0.7 2.2 1 1 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus 2-Hacid_dh_C PF02826.19 CBZ26086.1 - 0.075 12.4 0.1 0.13 11.6 0.1 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Aminotran_1_2 PF00155.21 CBZ26087.1 - 3.2e-60 204.2 0.0 4e-60 203.9 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 CBZ26087.1 - 0.0013 17.4 0.0 0.0021 16.7 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Sterol_MT_C PF08498.10 CBZ26089.1 - 2.1e-22 79.2 0.0 4.2e-22 78.2 0.0 1.5 1 0 0 1 1 1 1 Sterol methyltransferase C-terminal Methyltransf_11 PF08241.12 CBZ26089.1 - 8.6e-17 61.6 0.4 3.3e-16 59.7 0.1 2.2 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_25 PF13649.6 CBZ26089.1 - 3.9e-14 53.1 0.2 3.8e-13 50.0 0.0 2.4 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_31 PF13847.6 CBZ26089.1 - 1.8e-11 44.1 0.1 3.3e-11 43.2 0.1 1.5 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 CBZ26089.1 - 3.2e-09 36.5 0.0 5e-09 35.8 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.6 CBZ26089.1 - 1.4e-08 34.7 0.0 2.3e-08 34.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 CBZ26089.1 - 1.7e-07 30.8 0.0 3.1e-07 30.0 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 CBZ26089.1 - 9.9e-07 29.4 0.6 9.1e-06 26.4 0.0 2.7 4 0 0 4 4 4 1 Methyltransferase domain Methyltransf_15 PF09445.10 CBZ26089.1 - 0.031 13.9 0.3 0.049 13.2 0.3 1.3 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase Sterol_MT_C PF08498.10 CBZ26090.1 - 2.1e-22 79.2 0.0 4.2e-22 78.2 0.0 1.5 1 0 0 1 1 1 1 Sterol methyltransferase C-terminal Methyltransf_11 PF08241.12 CBZ26090.1 - 1e-16 61.3 0.3 4.1e-16 59.4 0.0 2.2 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_25 PF13649.6 CBZ26090.1 - 4e-14 53.1 0.2 4e-13 49.9 0.0 2.4 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_31 PF13847.6 CBZ26090.1 - 1.1e-11 44.7 0.1 2.1e-11 43.9 0.1 1.5 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 CBZ26090.1 - 2.9e-09 36.6 0.0 4.5e-09 36.0 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.6 CBZ26090.1 - 2e-08 34.3 0.0 3.3e-08 33.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 CBZ26090.1 - 1.8e-07 30.8 0.0 3.2e-07 29.9 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 CBZ26090.1 - 9.3e-07 29.5 0.6 8.8e-06 26.4 0.0 2.7 4 0 0 4 4 4 1 Methyltransferase domain Methyltransf_15 PF09445.10 CBZ26090.1 - 0.016 14.8 0.3 0.025 14.1 0.3 1.3 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase EF-hand_7 PF13499.6 CBZ26091.1 - 0.0007 20.0 0.0 0.0013 19.1 0.0 1.4 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.6 CBZ26091.1 - 0.015 15.2 0.0 10 6.4 0.1 2.5 2 0 0 2 2 2 0 EF-hand domain EF-hand_1 PF00036.32 CBZ26091.1 - 0.02 14.4 0.0 5.3 6.8 0.0 2.4 2 0 0 2 2 2 0 EF hand Cullin_Nedd8 PF10557.9 CBZ26092.1 - 8.6e-19 67.4 0.4 1.6e-18 66.5 0.4 1.5 1 0 0 1 1 1 1 Cullin protein neddylation domain Peptidase_S9 PF00326.21 CBZ26093.1 - 2.7e-31 108.7 0.0 5.4e-31 107.7 0.0 1.5 1 0 0 1 1 1 1 Prolyl oligopeptidase family DPPIV_N PF00930.21 CBZ26093.1 - 4.5e-24 84.9 0.0 8.4e-24 84.0 0.0 1.3 1 0 0 1 1 1 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Abhydrolase_6 PF12697.7 CBZ26093.1 - 0.043 14.4 0.5 0.14 12.7 0.0 1.9 1 1 1 2 2 2 0 Alpha/beta hydrolase family Peptidase_S15 PF02129.18 CBZ26093.1 - 0.14 11.7 0.0 0.63 9.6 0.0 1.8 1 1 0 2 2 2 0 X-Pro dipeptidyl-peptidase (S15 family) EF-hand_7 PF13499.6 CBZ26094.1 - 0.00012 22.4 0.0 0.09 13.2 0.0 2.5 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 CBZ26094.1 - 0.00016 21.3 0.0 0.011 15.6 0.0 2.6 2 0 0 2 2 2 1 EF-hand domain EF-hand_1 PF00036.32 CBZ26094.1 - 0.00091 18.6 0.0 0.0028 17.1 0.0 1.9 2 0 0 2 2 2 1 EF hand EF-hand_8 PF13833.6 CBZ26094.1 - 0.053 13.4 0.3 1.3 8.9 0.0 2.5 3 0 0 3 3 3 0 EF-hand domain pair EF-hand_5 PF13202.6 CBZ26094.1 - 0.071 12.6 0.0 0.24 11.0 0.0 2.0 1 0 0 1 1 1 0 EF hand DUF3228 PF11539.8 CBZ26094.1 - 0.13 11.8 0.2 0.2 11.1 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3228) FYVE PF01363.21 CBZ26095.1 - 4.2e-09 36.4 9.0 7e-09 35.7 9.0 1.3 1 0 0 1 1 1 1 FYVE zinc finger FYVE_2 PF02318.16 CBZ26095.1 - 0.067 13.4 7.6 0.17 12.1 7.7 1.6 1 1 0 1 1 1 0 FYVE-type zinc finger zf-CCHC_6 PF15288.6 CBZ26095.1 - 1.1 9.1 6.4 0.17 11.8 1.5 2.1 2 0 0 2 2 2 0 Zinc knuckle zf-RING_5 PF14634.6 CBZ26095.1 - 1.9 8.5 8.8 4.9 7.2 8.8 1.8 1 1 0 1 1 1 0 zinc-RING finger domain TRP PF06011.12 CBZ26096.1 - 0.15 10.8 0.1 0.21 10.3 0.1 1.1 1 0 0 1 1 1 0 Transient receptor potential (TRP) ion channel His_Phos_2 PF00328.22 CBZ26098.1 - 1.2e-12 47.9 0.1 7.9e-07 28.8 0.0 3.1 1 1 1 3 3 3 3 Histidine phosphatase superfamily (branch 2) RRM_1 PF00076.22 CBZ26099.1 - 0.053 13.4 0.0 0.14 11.9 0.0 1.7 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CAP_N PF01213.19 CBZ26099.1 - 10 5.5 11.9 5.6 6.3 10.0 1.6 1 1 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Plasmodium_Vir PF05795.11 CBZ26100.1 - 0.12 11.8 2.4 0.18 11.2 2.4 1.2 1 0 0 1 1 1 0 Plasmodium vivax Vir protein WD40 PF00400.32 CBZ26101.1 - 2.9e-16 59.5 19.1 2.9e-06 27.9 1.3 6.3 5 1 1 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBZ26101.1 - 1.1e-07 32.1 0.6 12 6.3 0.0 5.4 5 0 0 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain Nic96 PF04097.14 CBZ26102.1 - 1.2e-58 199.1 0.3 2.2e-58 198.2 0.3 1.4 1 1 0 1 1 1 1 Nup93/Nic96 SNAPc_SNAP43 PF09808.9 CBZ26103.1 - 0.0044 17.0 0.0 0.0064 16.4 0.0 1.2 1 0 0 1 1 1 1 Small nuclear RNA activating complex (SNAPc), subunit SNAP43 DEAD PF00270.29 CBZ26104.1 - 2.7e-25 89.2 0.0 3.6e-24 85.5 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CBZ26104.1 - 2.4e-24 85.8 0.0 4.5e-22 78.5 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain Helicase_C_2 PF13307.6 CBZ26104.1 - 0.0068 16.6 0.0 0.064 13.4 0.0 2.1 2 0 0 2 2 2 1 Helicase C-terminal domain ResIII PF04851.15 CBZ26104.1 - 0.018 15.0 0.0 0.5 10.4 0.0 2.3 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit AAA_22 PF13401.6 CBZ26104.1 - 0.023 15.0 0.0 13 6.1 0.0 2.9 2 1 1 3 3 3 0 AAA domain UTP25 PF06862.12 CBZ26104.1 - 0.062 12.1 0.0 0.93 8.2 0.0 2.4 3 0 0 3 3 3 0 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 FA_hydroxylase PF04116.13 CBZ26105.1 - 1.1e-21 77.5 13.2 1.1e-21 77.5 13.2 3.0 3 0 0 3 3 3 1 Fatty acid hydroxylase superfamily HEAT PF02985.22 CBZ26107.1 - 0.0057 16.8 7.2 2.5 8.6 0.1 4.9 4 0 0 4 4 4 2 HEAT repeat DUF4042 PF13251.6 CBZ26107.1 - 0.081 12.6 0.1 0.28 10.8 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4042) His_Phos_2 PF00328.22 CBZ26108.1 - 1.8e-09 37.4 0.8 0.047 13.0 0.0 3.1 1 1 1 3 3 3 3 Histidine phosphatase superfamily (branch 2) GDPD PF03009.17 CBZ26109.1 - 2e-37 129.3 0.0 2.8e-37 128.8 0.0 1.2 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family His_Phos_2 PF00328.22 CBZ26110.1 - 4.2e-07 29.7 0.4 0.00017 21.1 0.0 3.0 1 1 1 2 2 2 1 Histidine phosphatase superfamily (branch 2) RCC1 PF00415.18 CBZ26111.1 - 3.7e-20 72.3 13.3 2.4e-06 28.0 0.0 6.4 7 1 0 7 7 7 4 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 CBZ26111.1 - 9.2e-18 63.6 12.7 3.3e-06 26.7 0.1 4.1 3 0 0 3 3 3 3 Regulator of chromosome condensation (RCC1) repeat DUF4213 PF13938.6 CBZ26111.1 - 0.0017 18.6 1.0 1.4 9.2 0.1 2.9 2 1 0 2 2 2 2 Putative heavy-metal chelation Mur_ligase_M PF08245.12 CBZ26112.1 - 1.7e-09 37.9 0.2 6.4e-09 36.1 0.2 1.8 1 1 0 1 1 1 1 Mur ligase middle domain VRR_NUC PF08774.11 CBZ26113.1 - 4.9e-06 26.6 0.0 1.2e-05 25.3 0.0 1.7 1 0 0 1 1 1 1 VRR-NUC domain PEGSRP PF07623.11 CBZ26113.1 - 4.3 7.2 10.1 2 8.3 1.7 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1584) Pkinase PF00069.25 CBZ26114.1 - 9.3e-23 80.9 0.0 9.9e-11 41.5 0.0 3.4 3 1 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ26114.1 - 1.2e-09 37.8 0.0 2e-08 33.8 0.0 2.6 3 0 0 3 3 3 1 Protein tyrosine kinase PCI PF01399.27 CBZ26115.1 - 0.00019 21.9 0.0 0.28 11.7 0.0 3.1 3 1 0 3 3 3 2 PCI domain Methyltransf_11 PF08241.12 CBZ26116.1 - 3.9e-11 43.5 0.0 4.7e-07 30.4 0.0 3.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CBZ26116.1 - 6.6e-11 42.8 0.0 0.00014 22.5 0.0 3.6 1 1 2 3 3 3 3 Methyltransferase domain Methyltransf_23 PF13489.6 CBZ26116.1 - 4.3e-06 26.7 0.1 7.3e-06 25.9 0.1 1.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CBZ26116.1 - 0.0005 20.8 0.0 0.017 15.9 0.0 2.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CBZ26116.1 - 0.0022 17.8 0.0 7.3 6.4 0.0 3.1 3 0 0 3 3 3 2 Methyltransferase domain 2-oxoacid_dh PF00198.23 CBZ26117.1 - 2.7e-77 259.4 0.0 3.5e-77 259.0 0.0 1.1 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) E3_binding PF02817.17 CBZ26117.1 - 6.5e-12 45.6 0.6 2e-11 44.0 0.6 1.9 1 0 0 1 1 1 1 e3 binding domain Biotin_lipoyl PF00364.22 CBZ26117.1 - 1.8e-10 40.5 0.0 5.5e-10 38.9 0.0 1.9 2 0 0 2 2 2 1 Biotin-requiring enzyme Metallophos_2 PF12850.7 CBZ26118.1 - 1e-07 32.3 0.6 3.1e-06 27.5 0.6 2.2 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.28 CBZ26118.1 - 0.00027 21.5 0.1 0.00087 19.8 0.1 1.9 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase MMS22L_C PF14911.6 CBZ26119.1 - 0.08 12.0 0.0 0.18 10.8 0.0 1.6 1 0 0 1 1 1 0 S-phase genomic integrity recombination mediator, C-terminal Pentapeptide_4 PF13599.6 CBZ26120.1 - 3.9e-15 55.8 19.1 1.4e-09 38.0 7.4 2.8 2 1 2 4 4 4 2 Pentapeptide repeats (9 copies) Pentapeptide_3 PF13576.6 CBZ26120.1 - 1.7e-13 50.5 9.9 1.6e-05 25.0 2.5 4.0 3 1 1 4 4 4 3 Pentapeptide repeats (9 copies) Pentapeptide PF00805.22 CBZ26120.1 - 2.8e-11 42.8 14.1 0.00014 21.5 2.2 4.3 2 1 3 6 6 6 5 Pentapeptide repeats (8 copies) NPA PF16469.5 CBZ26121.1 - 0.88 10.2 9.7 0.06 13.9 1.3 2.4 2 1 0 2 2 2 0 Nematode polyprotein allergen ABA-1 PIN_8 PF18476.1 CBZ26121.1 - 1.8 8.3 10.3 1.5 8.6 4.1 2.1 1 1 0 2 2 2 0 PIN like domain FKBP_N PF01346.18 CBZ26121.1 - 10 7.2 8.4 3.6 8.6 0.1 2.5 2 1 0 2 2 2 0 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase Peptidase_M41 PF01434.18 CBZ26123.1 - 3.2e-55 187.0 0.1 5e-55 186.3 0.1 1.3 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.29 CBZ26123.1 - 2.4e-41 141.2 0.0 4.8e-41 140.3 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 CBZ26123.1 - 1.2e-06 28.2 0.4 4.1e-06 26.5 0.2 2.0 2 0 0 2 2 2 1 AAA+ lid domain AAA_5 PF07728.14 CBZ26123.1 - 1.1e-05 25.5 0.0 3.9e-05 23.7 0.0 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 CBZ26123.1 - 1.9e-05 25.1 0.1 0.00015 22.2 0.1 2.2 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 CBZ26123.1 - 3.4e-05 24.2 0.2 0.0015 18.8 0.3 2.9 2 1 1 3 3 2 1 AAA domain RuvB_N PF05496.12 CBZ26123.1 - 9.8e-05 22.2 0.0 0.00032 20.5 0.0 1.8 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_25 PF13481.6 CBZ26123.1 - 0.00021 20.9 0.6 0.064 12.8 0.2 2.4 1 1 1 2 2 2 1 AAA domain AAA_14 PF13173.6 CBZ26123.1 - 0.00043 20.3 0.0 0.0015 18.5 0.0 1.9 2 0 0 2 2 2 1 AAA domain TIP49 PF06068.13 CBZ26123.1 - 0.0011 18.3 0.0 0.0028 16.9 0.0 1.6 2 0 0 2 2 2 1 TIP49 P-loop domain AAA_18 PF13238.6 CBZ26123.1 - 0.0012 19.4 0.0 0.0031 18.0 0.0 1.8 1 0 0 1 1 1 1 AAA domain Rad17 PF03215.15 CBZ26123.1 - 0.0025 17.8 0.0 0.0055 16.7 0.0 1.5 1 0 0 1 1 1 1 Rad17 P-loop domain IstB_IS21 PF01695.17 CBZ26123.1 - 0.0025 17.6 0.0 0.0074 16.0 0.0 1.8 2 0 0 2 2 1 1 IstB-like ATP binding protein NACHT PF05729.12 CBZ26123.1 - 0.0027 17.6 0.2 0.016 15.1 0.1 2.1 1 1 0 2 2 2 1 NACHT domain AAA_17 PF13207.6 CBZ26123.1 - 0.0042 17.5 0.0 0.0091 16.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 CBZ26123.1 - 0.0055 16.1 0.2 0.012 15.0 0.2 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.22 CBZ26123.1 - 0.014 15.8 0.0 0.12 12.8 0.0 2.2 2 0 0 2 2 2 0 RNA helicase AAA_28 PF13521.6 CBZ26123.1 - 0.015 15.6 0.0 0.044 14.0 0.0 1.9 2 0 0 2 2 1 0 AAA domain AAA_2 PF07724.14 CBZ26123.1 - 0.021 14.9 0.0 0.079 13.1 0.0 2.0 1 1 0 1 1 1 0 AAA domain (Cdc48 subfamily) TsaE PF02367.17 CBZ26123.1 - 0.023 14.7 0.0 0.046 13.7 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_33 PF13671.6 CBZ26123.1 - 0.031 14.4 0.0 0.064 13.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 CBZ26123.1 - 0.068 12.4 0.1 0.13 11.5 0.1 1.4 1 0 0 1 1 1 0 Zeta toxin ABC_tran PF00005.27 CBZ26123.1 - 0.074 13.6 0.6 0.33 11.5 0.3 2.2 2 0 0 2 2 2 0 ABC transporter ATPase PF06745.13 CBZ26123.1 - 0.11 11.8 0.0 0.8 9.0 0.0 2.3 2 0 0 2 2 2 0 KaiC TniB PF05621.11 CBZ26123.1 - 0.15 11.4 0.0 4.2 6.7 0.0 2.5 2 0 0 2 2 2 0 Bacterial TniB protein Parvo_NS1 PF01057.17 CBZ26123.1 - 0.24 10.5 0.0 0.43 9.6 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Peptidase_M50B PF13398.6 CBZ26123.1 - 0.34 10.5 0.8 0.48 10.0 0.0 1.5 2 0 0 2 2 1 0 Peptidase M50B-like RIX1 PF08167.12 CBZ26124.1 - 2.5e-05 24.1 1.7 0.00011 22.1 1.7 2.1 1 0 0 1 1 1 1 rRNA processing/ribosome biogenesis HEAT_EZ PF13513.6 CBZ26124.1 - 0.00085 19.8 3.8 0.47 11.0 0.0 4.5 3 2 1 4 4 4 2 HEAT-like repeat IBN_N PF03810.19 CBZ26124.1 - 0.0045 16.9 2.1 0.042 13.8 0.1 3.4 3 1 0 3 3 3 1 Importin-beta N-terminal domain B56 PF01603.20 CBZ26124.1 - 0.068 12.1 0.0 0.21 10.5 0.0 1.8 2 0 0 2 2 2 0 Protein phosphatase 2A regulatory B subunit (B56 family) Tyr_Deacylase PF02580.16 CBZ26125.1 - 9.1e-46 156.0 0.0 1e-45 155.8 0.0 1.0 1 0 0 1 1 1 1 D-Tyr-tRNA(Tyr) deacylase MFS_1 PF07690.16 CBZ26127.1 - 2.2e-14 53.2 39.8 1.5e-13 50.4 26.8 2.6 1 1 1 2 2 2 2 Major Facilitator Superfamily Nodulin-like PF06813.13 CBZ26127.1 - 3.3e-12 46.4 9.5 3.3e-12 46.4 9.5 2.1 2 0 0 2 2 2 1 Nodulin-like TP6A_N PF04406.14 CBZ26129.1 - 3.7e-05 23.6 0.0 0.00038 20.4 0.0 2.3 2 0 0 2 2 2 1 Type IIB DNA topoisomerase DUF2399 PF09664.10 CBZ26129.1 - 0.024 14.6 0.0 0.042 13.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function C-terminus (DUF2399) NDK PF00334.19 CBZ26130.1 - 0.0015 18.5 0.0 0.056 13.5 0.0 3.1 3 0 0 3 3 3 1 Nucleoside diphosphate kinase HA2 PF04408.23 CBZ26134.1 - 4.4e-18 65.5 0.1 2e-17 63.4 0.0 2.2 2 0 0 2 2 2 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 CBZ26134.1 - 3.1e-17 62.7 0.0 2.7e-16 59.7 0.0 2.4 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 CBZ26134.1 - 1.1e-14 54.7 0.0 3.8e-14 53.0 0.0 1.9 2 0 0 2 2 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 CBZ26134.1 - 2e-08 34.2 0.1 1.6e-07 31.2 0.1 2.3 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_22 PF13401.6 CBZ26134.1 - 1.3e-06 28.8 0.9 5.5e-06 26.7 0.1 2.5 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 CBZ26134.1 - 4.5e-05 23.3 0.5 0.00012 21.9 0.1 1.9 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.17 CBZ26134.1 - 0.022 14.5 0.1 3.8 7.2 0.0 2.6 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_23 PF13476.6 CBZ26134.1 - 0.031 14.8 0.9 0.13 12.8 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.6 CBZ26134.1 - 0.042 14.2 0.1 0.13 12.6 0.1 1.8 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 CBZ26134.1 - 0.083 13.4 0.1 1 9.9 0.1 2.7 1 1 0 1 1 1 0 ABC transporter AAA_7 PF12775.7 CBZ26134.1 - 0.094 12.2 0.0 0.26 10.8 0.0 1.7 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_33 PF13671.6 CBZ26134.1 - 0.95 9.6 0.0 0.95 9.6 0.0 3.1 3 0 0 3 3 3 0 AAA domain AAA_11 PF13086.6 CBZ26134.1 - 6.1 6.5 6.4 35 4.1 0.0 3.1 3 0 0 3 3 3 0 AAA domain Vps5 PF09325.10 CBZ26136.1 - 0.0034 17.0 2.0 0.0035 16.9 1.3 1.3 1 1 0 1 1 1 1 Vps5 C terminal like RasGAP_C PF03836.15 CBZ26136.1 - 0.0071 16.5 0.6 0.0081 16.3 0.6 1.2 1 0 0 1 1 1 1 RasGAP C-terminus GAS PF13851.6 CBZ26136.1 - 0.011 15.1 2.2 0.012 15.0 2.2 1.1 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding APG6_N PF17675.1 CBZ26136.1 - 0.015 15.8 5.3 0.018 15.6 5.3 1.1 1 0 0 1 1 1 0 Apg6 coiled-coil region DUF2968 PF11180.8 CBZ26136.1 - 0.015 14.9 3.4 0.016 14.8 3.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) Spc7 PF08317.11 CBZ26136.1 - 0.026 13.4 3.8 0.026 13.4 3.8 1.0 1 0 0 1 1 1 0 Spc7 kinetochore protein CENP-F_leu_zip PF10473.9 CBZ26136.1 - 0.027 14.5 3.0 0.046 13.8 3.0 1.4 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Baculo_PEP_C PF04513.12 CBZ26136.1 - 0.057 13.5 3.6 0.092 12.8 3.6 1.4 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus UPF0242 PF06785.11 CBZ26136.1 - 0.064 13.4 1.4 0.063 13.4 1.4 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Phage_GP20 PF06810.11 CBZ26136.1 - 0.077 12.8 4.3 0.3 10.9 1.5 1.8 1 1 0 1 1 1 0 Phage minor structural protein GP20 Herpes_UL25 PF01499.16 CBZ26136.1 - 0.089 11.3 1.9 0.11 11.0 1.9 1.0 1 0 0 1 1 1 0 Herpesvirus UL25 family RmuC PF02646.16 CBZ26136.1 - 0.089 11.9 2.3 0.088 11.9 2.3 1.1 1 0 0 1 1 1 0 RmuC family DUF4407 PF14362.6 CBZ26136.1 - 0.1 11.9 2.7 0.098 12.0 2.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF2203 PF09969.9 CBZ26136.1 - 0.12 13.1 1.0 0.17 12.6 0.6 1.4 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) Spc24 PF08286.11 CBZ26136.1 - 0.18 12.1 1.7 0.22 11.8 1.7 1.3 1 0 0 1 1 1 0 Spc24 subunit of Ndc80 V_ATPase_I PF01496.19 CBZ26136.1 - 0.22 9.4 0.9 0.23 9.3 0.9 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF4140 PF13600.6 CBZ26136.1 - 0.49 10.9 5.1 0.98 9.9 5.1 1.5 1 0 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) GvpG PF05120.12 CBZ26136.1 - 0.5 10.4 3.8 0.76 9.8 3.8 1.5 1 1 0 1 1 1 0 Gas vesicle protein G OmpH PF03938.14 CBZ26136.1 - 0.55 10.6 7.7 0.64 10.4 7.7 1.2 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) ZapB PF06005.12 CBZ26136.1 - 0.57 10.7 6.4 6.2 7.3 6.4 2.1 1 1 0 1 1 1 0 Cell division protein ZapB SlyX PF04102.12 CBZ26136.1 - 0.69 10.6 5.4 11 6.8 5.3 2.1 1 1 0 1 1 1 0 SlyX DivIC PF04977.15 CBZ26136.1 - 0.74 9.6 8.1 42 4.0 8.2 2.1 1 1 0 1 1 1 0 Septum formation initiator NPV_P10 PF05531.12 CBZ26136.1 - 1.2 9.7 4.0 3.5 8.2 3.7 2.0 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein GIT_CC PF16559.5 CBZ26136.1 - 1.4 8.8 6.1 3.4 7.6 1.7 2.3 2 1 1 3 3 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor Ribosomal_S24e PF01282.19 CBZ26138.1 - 2e-26 91.8 0.0 3.8e-26 90.8 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein S24e Ribosomal_S24e PF01282.19 CBZ26139.1 - 2e-26 91.8 0.0 3.8e-26 90.8 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein S24e ASH PF15780.5 CBZ26140.1 - 2.8e-24 85.1 0.7 0.00046 20.3 0.0 9.5 10 0 0 10 10 10 5 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin Motile_Sperm PF00635.26 CBZ26140.1 - 2.7e-13 49.7 0.0 0.021 14.7 0.0 6.3 5 0 0 5 5 5 4 MSP (Major sperm protein) domain TMEM131_like PF12371.8 CBZ26140.1 - 0.00047 20.4 0.1 1.1 9.6 0.0 3.8 4 0 0 4 4 4 2 Transmembrane protein 131-like DUF1573 PF07610.11 CBZ26140.1 - 0.045 13.8 0.0 18 5.5 0.0 4.7 7 0 0 7 7 7 0 Protein of unknown function (DUF1573) ABC2_membrane PF01061.24 CBZ26141.1 - 1.7e-37 128.9 19.5 3.1e-37 128.0 19.5 1.4 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.27 CBZ26141.1 - 7.9e-22 78.2 0.0 1.4e-21 77.5 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 CBZ26141.1 - 2.5e-07 30.8 0.7 0.0086 15.9 0.1 2.2 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 CBZ26141.1 - 0.00018 21.9 2.5 0.0033 17.8 0.0 2.7 2 1 0 2 2 2 1 AAA ATPase domain AAA_29 PF13555.6 CBZ26141.1 - 0.00042 20.0 0.0 0.007 16.1 0.0 2.3 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_22 PF13401.6 CBZ26141.1 - 0.0043 17.3 0.1 0.022 15.0 0.1 2.2 1 1 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 CBZ26141.1 - 0.0073 16.2 0.1 0.016 15.1 0.1 1.5 1 0 0 1 1 1 1 RsgA GTPase IstB_IS21 PF01695.17 CBZ26141.1 - 0.024 14.4 0.2 0.091 12.5 0.0 1.9 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_28 PF13521.6 CBZ26141.1 - 0.055 13.7 0.1 0.16 12.2 0.1 1.8 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 CBZ26141.1 - 0.064 13.8 0.0 0.12 12.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 CBZ26141.1 - 0.065 12.9 7.9 0.21 11.3 0.2 2.7 3 1 0 3 3 2 0 AAA domain DUF5551 PF17705.1 CBZ26141.1 - 0.11 12.2 0.0 0.25 11.0 0.0 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5551) NACHT PF05729.12 CBZ26141.1 - 0.11 12.4 0.4 0.65 9.9 0.2 2.3 2 0 0 2 2 2 0 NACHT domain SMC_N PF02463.19 CBZ26141.1 - 0.17 11.3 0.0 1.5 8.2 0.0 2.1 1 1 0 1 1 1 0 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 CBZ26141.1 - 0.19 12.2 0.0 0.35 11.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain Rad17 PF03215.15 CBZ26141.1 - 0.24 11.3 0.0 0.4 10.6 0.0 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain Pox_A9 PF04835.12 CBZ26141.1 - 0.33 11.1 3.3 27 5.0 0.3 3.2 3 0 0 3 3 3 0 A9 protein conserved region AAA_33 PF13671.6 CBZ26141.1 - 0.83 9.8 2.9 1.2 9.3 0.1 2.3 2 0 0 2 2 2 0 AAA domain MCM PF00493.23 CBZ26142.1 - 0.0015 17.6 0.0 0.0025 17.0 0.0 1.3 1 0 0 1 1 1 1 MCM P-loop domain AAA_16 PF13191.6 CBZ26142.1 - 0.013 15.9 3.0 0.037 14.4 0.1 2.8 3 1 0 3 3 3 0 AAA ATPase domain DUF4054 PF13262.6 CBZ26142.1 - 0.17 12.0 2.4 0.22 11.5 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF4054) PHF5 PF03660.14 CBZ26144.1 - 3.3e-33 114.0 8.5 3.7e-33 113.9 8.5 1.0 1 0 0 1 1 1 1 PHF5-like protein zf-CHY PF05495.12 CBZ26144.1 - 0.61 10.6 9.6 2.4 8.7 9.1 1.9 1 1 1 2 2 2 0 CHY zinc finger FYVE_2 PF02318.16 CBZ26144.1 - 0.61 10.3 8.1 0.28 11.4 6.1 1.5 2 0 0 2 2 2 0 FYVE-type zinc finger DZR PF12773.7 CBZ26144.1 - 0.73 9.9 11.2 3.8 7.6 10.4 2.4 1 1 0 1 1 1 0 Double zinc ribbon zf-C3HC4_3 PF13920.6 CBZ26144.1 - 2.1 8.3 13.9 0.048 13.5 3.7 2.7 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zinc_ribbon_2 PF13240.6 CBZ26144.1 - 3.3 7.6 7.3 6.9 6.5 3.5 2.8 1 1 2 3 3 3 0 zinc-ribbon domain TF_Zn_Ribbon PF08271.12 CBZ26144.1 - 3.6 7.2 12.8 0.54 9.8 1.2 2.6 1 1 0 2 2 2 0 TFIIB zinc-binding zf-RING_2 PF13639.6 CBZ26145.1 - 5.8e-12 45.8 6.2 5.8e-12 45.8 6.2 2.4 3 0 0 3 3 2 1 Ring finger domain zf-RING_11 PF17123.5 CBZ26145.1 - 9.8e-10 38.0 3.3 9.8e-10 38.0 3.3 1.8 2 0 0 2 2 1 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 CBZ26145.1 - 3.1e-08 33.3 5.7 8.2e-08 32.0 5.7 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CBZ26145.1 - 6.8e-07 29.1 3.8 6.8e-07 29.1 3.8 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 CBZ26145.1 - 2.5e-06 27.7 7.3 1.5e-05 25.2 7.3 2.2 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 CBZ26145.1 - 3.6e-06 26.9 3.4 8.4e-06 25.7 3.4 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 CBZ26145.1 - 1e-05 25.4 4.7 2.7e-05 24.0 4.7 1.8 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 CBZ26145.1 - 1.1e-05 25.1 4.4 1.1e-05 25.1 4.4 2.7 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 CBZ26145.1 - 0.0015 18.1 4.6 0.0015 18.1 4.6 2.0 2 0 0 2 2 2 1 Zinc-ribbon, C4HC2 type PHD PF00628.29 CBZ26145.1 - 0.038 13.9 8.8 0.03 14.2 5.1 2.3 2 0 0 2 2 2 0 PHD-finger zf-ANAPC11 PF12861.7 CBZ26145.1 - 0.074 13.1 4.6 0.23 11.5 4.6 1.9 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_9 PF13901.6 CBZ26145.1 - 0.12 12.3 4.4 0.88 9.5 2.5 2.3 2 0 0 2 2 2 0 Putative zinc-RING and/or ribbon zf-RING_4 PF14570.6 CBZ26145.1 - 0.35 10.7 5.2 1 9.2 5.2 1.8 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain FANCL_C PF11793.8 CBZ26145.1 - 0.41 10.9 5.3 1.6 9.0 5.3 2.0 1 1 0 1 1 1 0 FANCL C-terminal domain Zn-ribbon_8 PF09723.10 CBZ26145.1 - 4.5 7.5 6.1 0.7 10.1 1.7 1.9 2 0 0 2 2 1 0 Zinc ribbon domain Prok-RING_1 PF14446.6 CBZ26145.1 - 5.7 6.9 8.8 2 8.4 3.7 2.2 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 PI3_PI4_kinase PF00454.27 CBZ26146.1 - 5.4e-28 98.5 0.0 9.6e-28 97.6 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase NUC194 PF08163.12 CBZ26146.1 - 5.1e-05 22.4 0.0 0.036 13.0 0.0 2.6 2 0 0 2 2 2 2 NUC194 domain FATC PF02260.20 CBZ26146.1 - 0.0049 16.7 0.0 0.016 15.1 0.0 1.9 1 0 0 1 1 1 1 FATC domain ATP-grasp_2 PF08442.10 CBZ26147.1 - 6.8e-65 218.4 4.1 1e-64 217.8 4.1 1.3 1 0 0 1 1 1 1 ATP-grasp domain Ligase_CoA PF00549.19 CBZ26147.1 - 3.2e-21 75.7 1.1 3.2e-21 75.7 1.1 2.5 3 0 0 3 3 3 1 CoA-ligase SID-1_RNA_chan PF13965.6 CBZ26148.1 - 0.15 10.5 0.9 0.15 10.4 0.9 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 KleE PF17394.2 CBZ26148.1 - 0.2 11.9 1.0 0.28 11.4 1.0 1.3 1 0 0 1 1 1 0 Uncharacterized KleE stable inheritance protein LtrA PF06772.11 CBZ26149.1 - 0.021 14.0 0.6 0.029 13.6 0.6 1.2 1 0 0 1 1 1 0 Bacterial low temperature requirement A protein (LtrA) Bromodomain PF00439.25 CBZ26150.1 - 2.4e-22 78.8 0.0 3.9e-22 78.1 0.0 1.3 1 0 0 1 1 1 1 Bromodomain DUF4600 PF15372.6 CBZ26150.1 - 0.026 15.0 1.1 0.049 14.1 1.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4600) DUF1635 PF07795.11 CBZ26150.1 - 0.5 10.2 3.7 0.85 9.4 3.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1635) Cwf_Cwc_15 PF04889.12 CBZ26150.1 - 2.4 7.8 16.2 3.1 7.5 16.2 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein ANAPC15 PF15243.6 CBZ26150.1 - 2.6 8.5 20.8 1.5e+03 -0.4 0.0 3.9 2 1 0 2 2 2 0 Anaphase-promoting complex subunit 15 GTP1_OBG PF01018.22 CBZ26151.1 - 1.7e-39 134.9 5.3 2.5e-39 134.4 5.3 1.2 1 0 0 1 1 1 1 GTP1/OBG MMR_HSR1 PF01926.23 CBZ26151.1 - 4.4e-18 65.4 0.0 7.6e-18 64.7 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 CBZ26151.1 - 1.7e-06 27.6 0.0 7.3e-05 22.3 0.0 2.3 2 0 0 2 2 2 1 Ferrous iron transport protein B DSHCT PF08148.12 CBZ26152.1 - 3.2e-45 153.7 0.4 3.2e-45 153.7 0.4 2.2 3 0 0 3 3 3 1 DSHCT (NUC185) domain rRNA_proc-arch PF13234.6 CBZ26152.1 - 1.5e-44 152.9 2.1 2e-44 152.6 0.7 1.8 2 0 0 2 2 2 1 rRNA-processing arch domain DEAD PF00270.29 CBZ26152.1 - 2.6e-22 79.5 0.5 3.7e-21 75.7 0.0 3.0 3 0 0 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CBZ26152.1 - 6.2e-07 29.7 0.0 2.5e-06 27.8 0.0 2.2 2 1 0 2 2 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 CBZ26152.1 - 1.3e-06 28.6 0.0 3e-06 27.3 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit ATPase_2 PF01637.18 CBZ26152.1 - 0.0059 16.5 1.1 0.027 14.4 0.0 2.3 2 0 0 2 2 2 1 ATPase domain predominantly from Archaea PhoH PF02562.16 CBZ26152.1 - 0.019 14.4 0.0 0.042 13.3 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein AAA_22 PF13401.6 CBZ26152.1 - 0.023 15.0 0.0 0.13 12.5 0.0 2.3 2 0 0 2 2 2 0 AAA domain T2SSE PF00437.20 CBZ26152.1 - 0.03 13.4 0.0 0.077 12.0 0.0 1.6 1 0 0 1 1 1 0 Type II/IV secretion system protein Syntaxin_2 PF14523.6 CBZ26152.1 - 0.031 14.7 4.2 0.22 11.9 0.9 3.3 3 1 1 4 4 3 0 Syntaxin-like protein FlxA PF14282.6 CBZ26152.1 - 0.034 14.1 6.1 0.069 13.1 6.1 1.4 1 0 0 1 1 1 0 FlxA-like protein Helicase_RecD PF05127.14 CBZ26152.1 - 0.089 12.6 0.9 5.7 6.7 0.0 2.6 2 0 0 2 2 2 0 Helicase MutS_III PF05192.18 CBZ26152.1 - 0.091 13.0 5.7 0.87 9.8 0.0 2.9 2 1 0 2 2 2 0 MutS domain III GSHPx PF00255.19 CBZ26153.1 - 1.2e-27 95.6 0.1 1.5e-27 95.3 0.1 1.1 1 0 0 1 1 1 1 Glutathione peroxidase AhpC-TSA PF00578.21 CBZ26153.1 - 0.0008 19.3 0.0 0.001 19.0 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 CBZ26153.1 - 0.0041 16.8 0.1 0.0055 16.4 0.1 1.1 1 0 0 1 1 1 1 Redoxin RNase_PH PF01138.21 CBZ26154.1 - 1.1e-29 103.6 0.5 1.6e-29 103.1 0.5 1.3 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 CBZ26154.1 - 8.9e-05 22.5 0.0 0.00019 21.4 0.0 1.6 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 DUF1623 PF07785.11 CBZ26154.1 - 0.048 13.8 0.6 0.087 13.0 0.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1623) E1_DerP2_DerF2 PF02221.15 CBZ26154.1 - 0.098 13.1 0.0 0.25 11.8 0.0 1.6 1 0 0 1 1 1 0 ML domain Adap_comp_sub PF00928.21 CBZ26155.1 - 4.4e-55 186.9 0.0 5.4e-55 186.6 0.0 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 CBZ26155.1 - 8.3e-05 22.5 0.3 0.00013 21.9 0.3 1.3 1 0 0 1 1 1 1 Clathrin adaptor complex small chain muHD PF10291.9 CBZ26155.1 - 0.02 14.3 0.1 0.029 13.8 0.1 1.3 1 0 0 1 1 1 0 Muniscin C-terminal mu homology domain RRM_1 PF00076.22 CBZ26156.1 - 8.6e-09 35.1 0.0 1.2e-08 34.6 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 CBZ26156.1 - 1.1e-06 28.2 0.0 1.2e-06 28.1 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Phage_Gp23 PF10669.9 CBZ26156.1 - 0.0091 16.3 2.6 0.013 15.9 2.6 1.2 1 0 0 1 1 1 1 Protein gp23 (Bacteriophage A118) DUF4523 PF15023.6 CBZ26156.1 - 0.17 11.7 0.3 0.26 11.1 0.1 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF4523) Cullin PF00888.22 CBZ26158.1 - 3.4e-63 214.2 0.1 4e-63 214.0 0.1 1.0 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 CBZ26158.1 - 1.1e-11 44.6 0.0 4.6e-11 42.6 0.0 2.2 1 0 0 1 1 1 1 Cullin protein neddylation domain Fibrillarin PF01269.17 CBZ26159.1 - 3.1e-100 333.9 0.0 3.5e-100 333.8 0.0 1.0 1 0 0 1 1 1 1 Fibrillarin GCD14 PF08704.10 CBZ26159.1 - 0.0034 17.1 0.0 0.0052 16.5 0.0 1.3 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit PCMT PF01135.19 CBZ26159.1 - 0.047 13.4 0.1 0.074 12.8 0.1 1.4 1 1 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Thioredoxin PF00085.20 CBZ26161.1 - 0.11 12.6 0.0 0.57 10.2 0.0 2.2 2 0 0 2 2 2 0 Thioredoxin vATP-synt_E PF01991.18 CBZ26162.1 - 1.2e-39 135.9 7.6 1.3e-39 135.7 7.6 1.0 1 0 0 1 1 1 1 ATP synthase (E/31 kDa) subunit Acyl-CoA_dh_N PF02771.16 CBZ26162.1 - 0.2 12.3 3.5 0.18 12.5 1.8 1.8 2 0 0 2 2 2 0 Acyl-CoA dehydrogenase, N-terminal domain YjeJ PF15922.5 CBZ26162.1 - 0.29 10.3 5.5 0.47 9.6 5.5 1.5 1 1 0 1 1 1 0 YjeJ-like HTH_32 PF13565.6 CBZ26162.1 - 0.31 11.7 3.6 0.88 10.2 0.9 2.8 1 1 1 2 2 2 0 Homeodomain-like domain DUF1266 PF06889.11 CBZ26163.1 - 0.059 13.4 0.2 0.11 12.5 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1266) Pesticin PF16754.5 CBZ26163.1 - 0.1 12.5 0.3 18 5.3 0.0 2.8 1 1 0 2 2 2 0 Bacterial toxin homologue of phage lysozyme, C-term EF-hand_8 PF13833.6 CBZ26164.1 - 5.9e-07 29.2 0.6 2.7e-05 23.9 0.0 2.7 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_7 PF13499.6 CBZ26164.1 - 8e-06 26.2 0.1 0.00065 20.1 0.0 2.9 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_1 PF00036.32 CBZ26164.1 - 0.046 13.3 0.2 13 5.6 0.0 3.5 4 0 0 4 4 4 0 EF hand EF-hand_6 PF13405.6 CBZ26164.1 - 0.13 12.2 0.0 40 4.5 0.0 3.5 4 0 0 4 4 4 0 EF-hand domain Pro_isomerase PF00160.21 CBZ26165.1 - 1.7e-37 129.1 0.0 2e-37 128.9 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD ArfGap PF01412.18 CBZ26167.1 - 3.7e-24 85.1 0.0 5.4e-24 84.5 0.0 1.2 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf Zn_Tnp_IS1595 PF12760.7 CBZ26167.1 - 0.17 11.9 0.1 0.31 11.0 0.1 1.5 1 0 0 1 1 1 0 Transposase zinc-ribbon domain TBCC PF07986.12 CBZ26168.1 - 5.4e-26 90.7 1.0 1e-25 89.8 1.0 1.4 1 0 0 1 1 1 1 Tubulin binding cofactor C TBCC_N PF16752.5 CBZ26168.1 - 7.8e-05 23.1 6.6 0.00016 22.1 6.6 1.4 1 0 0 1 1 1 1 Tubulin-specific chaperone C N-terminal domain TAN PF11640.8 CBZ26168.1 - 0.02 15.0 0.7 0.034 14.3 0.7 1.3 1 0 0 1 1 1 0 Telomere-length maintenance and DNA damage repair Jnk-SapK_ap_N PF09744.9 CBZ26168.1 - 8.6 6.6 13.3 14 5.8 13.3 1.4 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 cobW PF02492.19 CBZ26169.1 - 2.7e-48 163.9 0.2 3.6e-48 163.5 0.2 1.2 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain RsgA_GTPase PF03193.16 CBZ26169.1 - 0.00065 19.6 0.2 0.76 9.7 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase ATP_bind_1 PF03029.17 CBZ26169.1 - 0.0027 17.5 0.0 0.0043 16.9 0.0 1.3 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_18 PF13238.6 CBZ26169.1 - 0.0057 17.2 0.3 0.51 10.9 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 CBZ26169.1 - 0.032 14.0 0.1 0.15 11.8 0.0 2.0 2 0 0 2 2 2 0 P-loop containing region of AAA domain CobW_C PF07683.14 CBZ26169.1 - 0.042 13.8 0.0 0.076 12.9 0.0 1.4 1 0 0 1 1 1 0 Cobalamin synthesis protein cobW C-terminal domain MobB PF03205.14 CBZ26169.1 - 0.042 13.8 0.3 0.58 10.1 0.3 2.3 1 1 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_30 PF13604.6 CBZ26169.1 - 0.042 13.6 0.3 0.35 10.5 0.0 2.3 2 1 0 2 2 2 0 AAA domain AAA_22 PF13401.6 CBZ26169.1 - 0.074 13.3 0.0 0.17 12.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 CBZ26169.1 - 0.075 13.0 0.0 0.15 12.0 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_33 PF13671.6 CBZ26169.1 - 0.12 12.5 0.1 0.29 11.3 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 CBZ26169.1 - 0.14 12.5 0.1 0.47 10.8 0.0 1.8 2 0 0 2 2 2 0 AAA ATPase domain Guanylate_cyc PF00211.20 CBZ26170.1 - 8.8e-36 123.2 0.0 1.5e-35 122.5 0.0 1.4 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain DUF1935 PF09149.10 CBZ26170.1 - 7.7e-29 100.1 0.0 1.9e-28 98.9 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1935) Peripla_BP_6 PF13458.6 CBZ26170.1 - 3.1e-05 23.8 6.2 0.025 14.3 1.9 2.4 2 0 0 2 2 2 2 Periplasmic binding protein DUF4841 PF16129.5 CBZ26170.1 - 0.0098 16.1 0.1 0.027 14.7 0.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4841) CYYR1 PF10873.8 CBZ26170.1 - 0.019 15.5 0.4 0.065 13.7 0.4 1.9 1 0 0 1 1 1 0 Cysteine and tyrosine-rich protein 1 zf-CCHC PF00098.23 CBZ26171.1 - 2e-18 65.5 84.1 0.00035 20.5 1.0 9.9 10 0 0 10 10 10 8 Zinc knuckle zf-CCHC_2 PF13696.6 CBZ26171.1 - 1.8e-07 30.8 25.6 8.2e-05 22.3 2.4 9.6 8 1 1 9 9 9 4 Zinc knuckle NYN PF01936.18 CBZ26171.1 - 0.016 15.7 0.0 0.035 14.6 0.0 1.6 1 1 0 1 1 1 0 NYN domain zf-CCHC_4 PF14392.6 CBZ26171.1 - 0.35 10.6 83.3 0.03 14.1 2.8 10.1 6 3 4 10 10 10 0 Zinc knuckle Topoisom_bac PF01131.20 CBZ26172.1 - 6.6e-104 348.2 0.0 9.5e-104 347.7 0.0 1.1 1 0 0 1 1 1 1 DNA topoisomerase Toprim PF01751.22 CBZ26172.1 - 1.4e-16 60.5 0.0 4.2e-16 59.0 0.0 1.8 2 0 0 2 2 2 1 Toprim domain zf-C4_Topoisom PF01396.19 CBZ26172.1 - 2.8e-06 27.0 0.6 2.8e-06 27.0 0.6 5.0 5 1 0 5 5 5 1 Topoisomerase DNA binding C4 zinc finger zf-GRF PF06839.12 CBZ26172.1 - 1.1e-05 25.5 3.5 1.1e-05 25.5 3.5 2.5 2 0 0 2 2 2 1 GRF zinc finger Cys_rich_CPCC PF14206.6 CBZ26172.1 - 0.017 14.9 0.6 0.072 12.9 0.4 2.2 2 0 0 2 2 2 0 Cysteine-rich CPCC Terminase_GpA PF05876.12 CBZ26172.1 - 0.11 11.0 0.6 0.18 10.3 0.6 1.2 1 0 0 1 1 1 0 Phage terminase large subunit (GpA) Zn_ribbon_recom PF13408.6 CBZ26172.1 - 0.63 10.6 5.1 1.3 9.5 0.1 2.9 2 0 0 2 2 2 0 Recombinase zinc beta ribbon domain 14-3-3 PF00244.20 CBZ26173.1 - 6.7e-85 284.1 1.0 7.7e-85 283.9 1.0 1.0 1 0 0 1 1 1 1 14-3-3 protein TPR_12 PF13424.6 CBZ26173.1 - 0.28 11.5 3.7 0.32 11.3 0.8 2.4 2 1 1 3 3 3 0 Tetratricopeptide repeat CdvA PF18822.1 CBZ26174.1 - 0.0067 16.3 2.9 0.0067 16.3 2.9 7.0 4 1 3 8 8 8 3 CdvA-like coiled-coil domain Matrilin_ccoil PF10393.9 CBZ26174.1 - 0.021 14.7 11.6 0.22 11.4 0.4 4.4 3 0 0 3 3 3 0 Trimeric coiled-coil oligomerisation domain of matrilin Acetyltransf_17 PF17668.1 CBZ26174.1 - 0.031 15.1 1.3 0.031 15.1 1.3 3.3 3 1 0 3 3 3 0 Acetyltransferase (GNAT) domain GMC_oxred_N PF00732.19 CBZ26175.1 - 6.5e-48 163.6 0.0 1.1e-47 162.8 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 CBZ26175.1 - 2.1e-21 77.0 0.1 3.9e-21 76.1 0.1 1.5 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 CBZ26175.1 - 1.8e-08 33.9 6.8 0.00053 19.2 2.0 3.1 3 0 0 3 3 3 2 FAD binding domain DAO PF01266.24 CBZ26175.1 - 3.5e-06 26.8 5.6 0.00014 21.6 0.8 3.0 2 1 1 3 3 3 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 CBZ26175.1 - 4.2e-05 22.9 0.2 0.0018 17.6 0.0 2.7 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 CBZ26175.1 - 0.0031 17.7 1.2 0.012 15.8 1.2 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.22 CBZ26175.1 - 0.012 14.7 1.3 0.31 10.1 2.1 2.1 2 0 0 2 2 2 0 Glucose inhibited division protein A Lycopene_cycl PF05834.12 CBZ26175.1 - 0.015 14.4 1.1 0.015 14.4 1.1 1.6 2 0 0 2 2 2 0 Lycopene cyclase protein HI0933_like PF03486.14 CBZ26175.1 - 0.033 12.9 1.9 0.053 12.2 1.0 1.6 2 0 0 2 2 2 0 HI0933-like protein Thi4 PF01946.17 CBZ26175.1 - 0.033 13.4 0.2 0.07 12.4 0.2 1.5 1 0 0 1 1 1 0 Thi4 family FAD_oxidored PF12831.7 CBZ26175.1 - 0.039 13.3 2.7 0.45 9.8 1.8 2.1 2 0 0 2 2 2 0 FAD dependent oxidoreductase DUF4679 PF15728.5 CBZ26177.1 - 0.43 9.6 6.3 0.33 9.9 3.9 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4679) DUF1712 PF08217.11 CBZ26178.1 - 0.00017 20.2 0.0 0.00025 19.7 0.0 1.2 1 0 0 1 1 1 1 Fungal domain of unknown function (DUF1712) Ribosomal_L20 PF00453.18 CBZ26179.1 - 0.034 14.3 0.8 0.051 13.7 0.8 1.3 1 0 0 1 1 1 0 Ribosomal protein L20 Ribosomal_L22e PF01776.17 CBZ26180.1 - 3.1e-36 124.1 3.7 3.9e-36 123.7 3.7 1.1 1 0 0 1 1 1 1 Ribosomal L22e protein family ECH_2 PF16113.5 CBZ26181.1 - 2e-21 76.8 0.0 2.1e-11 43.9 0.0 4.1 3 1 0 3 3 3 2 Enoyl-CoA hydratase/isomerase ECH_1 PF00378.20 CBZ26181.1 - 3.3e-13 49.5 0.0 7.2e-08 32.0 0.0 2.3 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase EPO_TPO PF00758.18 CBZ26181.1 - 0.15 12.1 0.0 14 5.7 0.0 2.4 1 1 1 2 2 2 0 Erythropoietin/thrombopoietin Macro PF01661.21 CBZ26182.1 - 0.0018 18.3 0.0 0.0028 17.7 0.0 1.3 1 0 0 1 1 1 1 Macro domain HATPase_c_2 PF13581.6 CBZ26183.1 - 0.091 12.7 4.1 0.41 10.6 4.1 2.2 1 0 0 1 1 1 0 Histidine kinase-like ATPase domain Equine_IAV_S2 PF06502.11 CBZ26183.1 - 0.28 11.3 1.3 0.79 9.8 1.3 1.7 1 0 0 1 1 1 0 Equine infectious anaemia virus S2 protein Actin PF00022.19 CBZ26184.1 - 4.1e-99 332.0 0.0 2.6e-98 329.3 0.0 1.8 1 1 0 1 1 1 1 Actin FtsA PF14450.6 CBZ26184.1 - 0.077 13.4 0.0 0.55 10.7 0.0 2.2 2 1 0 2 2 2 0 Cell division protein FtsA Bac_export_2 PF01312.19 CBZ26185.1 - 0.14 11.3 0.0 0.17 11.1 0.0 1.1 1 0 0 1 1 1 0 FlhB HrpN YscU SpaS Family Piezo_RRas_bdg PF12166.8 CBZ26187.1 - 1.1e-90 305.0 0.0 1.7e-90 304.4 0.0 1.3 1 0 0 1 1 1 1 Piezo non-specific cation channel, R-Ras-binding domain Bromodomain PF00439.25 CBZ26189.1 - 1.9e-13 50.3 0.0 4e-13 49.2 0.0 1.6 1 0 0 1 1 1 1 Bromodomain YtzH PF14165.6 CBZ26189.1 - 0.11 12.9 0.6 0.28 11.6 0.1 2.0 2 1 1 3 3 3 0 YtzH-like protein BET PF17035.5 CBZ26189.1 - 0.14 12.3 0.3 0.29 11.4 0.3 1.6 1 0 0 1 1 1 0 Bromodomain extra-terminal - transcription regulation Ribosomal_L29e PF01779.17 CBZ26192.1 - 1.7e-12 47.4 5.8 1.7e-12 47.4 5.8 1.9 2 0 0 2 2 2 1 Ribosomal L29e protein family Spo7_2_N PF15407.6 CBZ26192.1 - 0.087 12.5 0.5 0.12 12.0 0.5 1.5 1 1 0 1 1 1 0 Sporulation protein family 7 Ribosomal_L29e PF01779.17 CBZ26193.1 - 1.7e-12 47.4 5.8 1.7e-12 47.4 5.8 1.9 2 0 0 2 2 2 1 Ribosomal L29e protein family Spo7_2_N PF15407.6 CBZ26193.1 - 0.087 12.5 0.5 0.12 12.0 0.5 1.5 1 1 0 1 1 1 0 Sporulation protein family 7 adh_short PF00106.25 CBZ26194.1 - 1.8e-37 128.7 0.0 2.6e-37 128.2 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CBZ26194.1 - 2.7e-15 56.5 0.0 4.8e-15 55.7 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CBZ26194.1 - 6.3e-10 39.2 1.2 1.3e-08 35.0 1.2 2.2 1 1 0 1 1 1 1 KR domain Methyltransf_31 PF13847.6 CBZ26194.1 - 0.00032 20.5 0.0 0.00079 19.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 CBZ26194.1 - 0.042 13.2 0.0 0.065 12.6 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family DUF1776 PF08643.10 CBZ26194.1 - 0.12 11.7 0.0 0.19 11.1 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) 3HCDH_N PF02737.18 CBZ26194.1 - 0.16 11.8 0.1 0.27 11.1 0.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Polysacc_synt_2 PF02719.15 CBZ26194.1 - 0.19 10.8 0.0 0.29 10.2 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Pyr_redox PF00070.27 CBZ26194.1 - 0.24 12.0 0.5 0.44 11.1 0.5 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Vps26 PF03643.15 CBZ26195.1 - 2.9e-53 180.7 0.7 3.5e-53 180.4 0.7 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 Arrestin_N PF00339.29 CBZ26195.1 - 0.00036 20.6 1.6 0.61 10.1 0.0 3.1 2 1 1 3 3 3 2 Arrestin (or S-antigen), N-terminal domain CRAL_TRIO PF00650.20 CBZ26196.1 - 4.8e-29 101.1 0.0 6.9e-29 100.6 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.6 CBZ26196.1 - 0.0039 17.4 0.0 0.0072 16.5 0.0 1.3 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain Snf7 PF03357.21 CBZ26197.1 - 7e-27 94.1 29.5 7e-27 94.1 29.5 2.0 1 1 1 2 2 2 1 Snf7 GUCT PF08152.12 CBZ26197.1 - 1.5 9.2 6.2 2.1 8.7 0.4 2.6 2 1 0 2 2 2 0 GUCT (NUC152) domain Glyco_transf_25 PF01755.17 CBZ26198.1 - 5.9e-13 49.1 0.0 1.4e-12 47.9 0.0 1.6 1 1 0 1 1 1 1 Glycosyltransferase family 25 (LPS biosynthesis protein) NIPSNAP PF07978.13 CBZ26199.1 - 4.7e-14 52.4 0.1 1.1e-13 51.2 0.0 1.6 2 0 0 2 2 2 1 NIPSNAP Transket_pyr PF02779.24 CBZ26200.1 - 1.1e-55 188.1 0.0 5.5e-55 185.8 0.0 2.0 2 0 0 2 2 2 1 Transketolase, pyrimidine binding domain E1_dh PF00676.20 CBZ26200.1 - 4.9e-52 176.7 0.0 8.1e-52 176.0 0.0 1.2 1 0 0 1 1 1 1 Dehydrogenase E1 component OxoGdeHyase_C PF16870.5 CBZ26200.1 - 6.3e-44 149.3 0.1 1.1e-43 148.5 0.1 1.5 1 0 0 1 1 1 1 2-oxoglutarate dehydrogenase C-terminal 2-oxogl_dehyd_N PF16078.5 CBZ26200.1 - 2.3e-15 55.9 0.5 5.5e-15 54.7 0.5 1.6 1 0 0 1 1 1 1 2-oxoglutarate dehydrogenase N-terminus SMAP PF15477.6 CBZ26201.1 - 2e-10 41.4 5.8 2e-10 41.4 5.8 2.3 2 1 0 2 2 2 1 Small acidic protein family Herpes_UL25 PF01499.16 CBZ26201.1 - 0.23 9.9 3.8 0.26 9.8 3.3 1.2 1 1 0 1 1 1 0 Herpesvirus UL25 family SRP-alpha_N PF04086.13 CBZ26201.1 - 0.28 11.1 10.1 0.36 10.7 10.1 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal DUF2870 PF11069.8 CBZ26202.1 - 4.2e-24 84.8 0.0 8.9e-24 83.7 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2870) DivIC PF04977.15 CBZ26203.1 - 0.017 14.9 0.2 0.017 14.9 0.2 3.1 3 0 0 3 3 3 0 Septum formation initiator DUF3658 PF12395.8 CBZ26203.1 - 0.018 14.9 1.5 0.86 9.5 0.1 3.0 2 0 0 2 2 2 0 Protein of unknown function Rota_NSP4 PF01452.16 CBZ26203.1 - 0.021 14.5 2.1 0.041 13.6 2.1 1.3 1 0 0 1 1 1 0 Rotavirus non structural protein Shugoshin_N PF07558.11 CBZ26203.1 - 0.26 11.2 1.9 0.59 10.1 1.9 1.6 1 0 0 1 1 1 0 Shugoshin N-terminal coiled-coil region YabA PF06156.13 CBZ26203.1 - 0.28 11.9 0.1 0.28 11.9 0.1 2.9 2 1 0 2 2 2 0 Initiation control protein YabA CAP_N PF01213.19 CBZ26204.1 - 0.17 11.4 0.5 0.3 10.5 0.5 1.4 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal DUF2150 PF09920.9 CBZ26205.1 - 0.0089 16.0 0.2 0.038 14.0 0.0 1.9 1 1 1 2 2 2 1 Uncharacterized protein conserved in archaea (DUF2150) COE1_DBD PF16422.5 CBZ26205.1 - 0.16 11.4 0.1 0.23 10.9 0.1 1.1 1 0 0 1 1 1 0 Transcription factor COE1 DNA-binding domain ubiquitin PF00240.23 CBZ26206.1 - 1.4e-31 108.1 0.2 1.5e-31 107.9 0.2 1.0 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 CBZ26206.1 - 8.1e-15 54.4 0.1 9.1e-15 54.2 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 CBZ26206.1 - 8.2e-06 26.2 0.0 4.1e-05 24.0 0.0 1.8 1 1 0 1 1 1 1 Ubiquitin-like domain TBK1_ULD PF18396.1 CBZ26206.1 - 0.0011 18.8 0.0 0.0013 18.6 0.0 1.1 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain Ubiquitin_5 PF18037.1 CBZ26206.1 - 0.0018 18.6 0.0 0.002 18.4 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-like domain Rad60-SLD_2 PF13881.6 CBZ26206.1 - 0.0063 16.6 0.0 0.015 15.4 0.0 1.6 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 CBZ26206.1 - 0.12 13.0 0.0 0.14 12.7 0.0 1.2 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain SQS_PSY PF00494.19 CBZ26209.1 - 2.5e-13 50.2 0.0 3.9e-13 49.5 0.0 1.2 1 0 0 1 1 1 1 Squalene/phytoene synthase TetR_C_20 PF17925.1 CBZ26209.1 - 0.057 13.7 0.0 0.13 12.6 0.0 1.5 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain SRP54 PF00448.22 CBZ26210.1 - 4.5e-54 183.1 0.1 1.1e-53 181.8 0.1 1.7 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain SRP-alpha_N PF04086.13 CBZ26210.1 - 1.8e-23 83.9 1.0 2.7e-23 83.3 1.0 1.3 1 0 0 1 1 1 1 Signal recognition particle, alpha subunit, N-terminal SRP54_N PF02881.19 CBZ26210.1 - 1.1e-09 38.4 0.0 2.5e-09 37.2 0.0 1.6 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain AAA_30 PF13604.6 CBZ26210.1 - 8.9e-06 25.6 0.3 1.9e-05 24.4 0.3 1.6 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 CBZ26210.1 - 2.8e-05 24.4 0.0 0.00013 22.2 0.0 2.2 1 1 0 1 1 1 1 AAA domain APS_kinase PF01583.20 CBZ26210.1 - 0.00035 20.5 0.1 0.0046 16.9 0.0 2.3 2 0 0 2 2 2 1 Adenylylsulphate kinase Zeta_toxin PF06414.12 CBZ26210.1 - 0.0012 18.2 0.1 0.0077 15.5 0.0 2.4 2 1 0 2 2 2 1 Zeta toxin AAA_16 PF13191.6 CBZ26210.1 - 0.0012 19.3 0.0 0.0041 17.5 0.0 2.0 1 1 0 1 1 1 1 AAA ATPase domain MeaB PF03308.16 CBZ26210.1 - 0.0013 17.7 0.0 0.0034 16.4 0.0 1.6 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_24 PF13479.6 CBZ26210.1 - 0.002 17.9 0.0 0.068 12.9 0.0 3.1 3 1 0 3 3 3 1 AAA domain NTPase_1 PF03266.15 CBZ26210.1 - 0.0037 17.2 0.0 0.57 10.1 0.0 2.4 2 0 0 2 2 2 1 NTPase NACHT PF05729.12 CBZ26210.1 - 0.006 16.5 0.2 2.8 7.8 0.0 3.2 3 0 0 3 3 3 1 NACHT domain CbiA PF01656.23 CBZ26210.1 - 0.0095 16.0 1.1 0.3 11.1 0.1 2.8 3 0 0 3 3 3 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_17 PF13207.6 CBZ26210.1 - 0.0098 16.3 0.0 0.028 14.8 0.0 1.8 1 0 0 1 1 1 1 AAA domain ETF PF01012.21 CBZ26210.1 - 0.012 15.5 0.3 0.13 12.1 0.1 2.3 2 0 0 2 2 2 0 Electron transfer flavoprotein domain MMR_HSR1 PF01926.23 CBZ26210.1 - 0.028 14.5 1.4 0.39 10.8 0.8 2.9 3 1 0 3 3 2 0 50S ribosome-binding GTPase DAP3 PF10236.9 CBZ26210.1 - 0.043 13.0 0.0 0.08 12.1 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 ArsA_ATPase PF02374.15 CBZ26210.1 - 0.057 12.6 0.5 0.17 11.0 0.1 1.9 2 0 0 2 2 2 0 Anion-transporting ATPase AAA_33 PF13671.6 CBZ26210.1 - 0.063 13.4 0.0 0.17 12.0 0.0 1.8 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 CBZ26210.1 - 0.063 13.2 0.0 1.5 8.7 0.0 2.6 2 0 0 2 2 2 0 RsgA GTPase ABC_tran PF00005.27 CBZ26210.1 - 0.13 12.8 0.0 0.33 11.5 0.0 1.7 1 0 0 1 1 1 0 ABC transporter Longin PF13774.6 CBZ26210.1 - 0.16 12.0 0.2 0.35 10.9 0.2 1.6 1 0 0 1 1 1 0 Regulated-SNARE-like domain DUF2009 PF09418.10 CBZ26211.1 - 1e-158 529.2 0.0 1.2e-158 529.0 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2009) PALP PF00291.25 CBZ26212.1 - 8.4e-59 199.4 0.3 9.6e-59 199.2 0.3 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme EF-hand_7 PF13499.6 CBZ26215.1 - 8.9e-10 38.9 1.7 2.6e-09 37.4 0.5 1.9 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_8 PF13833.6 CBZ26215.1 - 1.1e-07 31.6 0.4 0.0036 17.1 0.1 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 CBZ26215.1 - 0.0011 18.7 0.4 0.019 14.8 0.0 2.6 3 1 0 3 3 3 1 EF-hand domain EF-hand_1 PF00036.32 CBZ26215.1 - 0.0019 17.6 1.3 0.2 11.3 0.0 3.4 4 0 0 4 4 4 1 EF hand EF-hand_5 PF13202.6 CBZ26215.1 - 0.0061 16.0 0.1 0.016 14.7 0.1 1.7 1 0 0 1 1 1 1 EF hand EF-hand_14 PF17959.1 CBZ26215.1 - 0.064 13.6 0.0 0.14 12.5 0.0 1.6 1 1 1 2 2 2 0 EF-hand domain Sigma70_r1_1 PF03979.14 CBZ26215.1 - 0.11 12.5 0.0 0.35 10.9 0.0 1.7 1 1 0 1 1 1 0 Sigma-70 factor, region 1.1 Peptidase_A25 PF03418.14 CBZ26215.1 - 0.13 11.1 0.0 0.13 11.1 0.0 1.0 1 0 0 1 1 1 0 Germination protease Shisa PF13908.6 CBZ26216.1 - 0.0012 19.2 0.3 0.0027 18.0 0.3 1.7 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator TMEM51 PF15345.6 CBZ26216.1 - 0.011 15.6 0.7 0.021 14.7 0.7 1.4 1 0 0 1 1 1 0 Transmembrane protein 51 Miga PF10265.9 CBZ26216.1 - 0.021 13.8 0.9 0.028 13.4 0.9 1.1 1 0 0 1 1 1 0 Mitoguardin DUF3481 PF11980.8 CBZ26216.1 - 0.022 14.5 0.1 0.045 13.4 0.1 1.5 1 0 0 1 1 1 0 C-terminal domain of neuropilin glycoprotein TMEM154 PF15102.6 CBZ26216.1 - 0.022 14.7 0.0 0.042 13.8 0.0 1.6 1 1 0 1 1 1 0 TMEM154 protein family TMEM52 PF14979.6 CBZ26216.1 - 0.023 14.6 0.1 0.072 13.0 0.1 1.9 1 0 0 1 1 1 0 Transmembrane 52 MLANA PF14991.6 CBZ26216.1 - 0.044 14.1 4.8 0.053 13.8 0.1 2.3 2 0 0 2 2 2 0 Protein melan-A Herpes_gE PF02480.16 CBZ26216.1 - 0.048 12.4 0.7 0.073 11.8 0.7 1.3 1 1 0 1 1 1 0 Alphaherpesvirus glycoprotein E BatD PF13584.6 CBZ26216.1 - 0.051 12.4 0.1 0.072 11.9 0.1 1.2 1 0 0 1 1 1 0 Oxygen tolerance MAS20 PF02064.15 CBZ26216.1 - 0.053 13.6 3.5 0.082 13.0 3.5 1.3 1 0 0 1 1 1 0 MAS20 protein import receptor DAG1 PF05454.11 CBZ26216.1 - 0.06 12.7 1.2 0.065 12.6 0.0 1.7 2 0 0 2 2 2 0 Dystroglycan (Dystrophin-associated glycoprotein 1) Inositol_P PF00459.25 CBZ26216.1 - 0.088 12.3 0.0 0.12 11.8 0.0 1.2 1 0 0 1 1 1 0 Inositol monophosphatase family Adeno_E3_CR2 PF02439.15 CBZ26216.1 - 0.15 11.8 3.3 0.29 10.9 3.3 1.5 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 TMIE PF16038.5 CBZ26216.1 - 0.2 11.6 0.6 0.36 10.7 0.6 1.4 1 0 0 1 1 1 0 TMIE protein EphA2_TM PF14575.6 CBZ26216.1 - 0.25 12.2 1.7 0.45 11.4 1.4 1.6 1 1 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain EMC3_TMCO1 PF01956.16 CBZ26216.1 - 0.37 10.5 1.1 0.57 9.9 1.1 1.3 1 0 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like PVL_ORF50 PF07768.11 CBZ26216.1 - 0.48 10.7 2.2 0.78 10.1 2.2 1.4 1 0 0 1 1 1 0 PVL ORF-50-like family HemY_N PF07219.13 CBZ26216.1 - 0.94 9.7 9.6 2.1 8.6 9.6 1.5 1 0 0 1 1 1 0 HemY protein N-terminus WD40 PF00400.32 CBZ26218.1 - 5.5e-11 42.8 10.6 0.0082 17.0 0.2 5.6 5 0 0 5 5 5 5 WD domain, G-beta repeat DUF1619 PF07773.11 CBZ26220.1 - 9.4e-47 160.5 1.2 1.8e-44 153.0 1.0 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF1619) NUDIX PF00293.28 CBZ26221.1 - 1.8e-11 44.2 0.0 3.2e-11 43.4 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain EF-hand_1 PF00036.32 CBZ26223.1 - 2.1e-26 89.4 6.2 5.4e-07 28.7 0.8 4.3 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 CBZ26223.1 - 1e-25 89.9 2.1 2.7e-13 50.2 0.1 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 CBZ26223.1 - 8.9e-22 75.1 3.5 2.2e-06 27.1 0.1 4.6 4 0 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.6 CBZ26223.1 - 2e-18 65.9 6.4 2.1e-08 33.9 0.6 3.3 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_5 PF13202.6 CBZ26223.1 - 9.3e-14 50.2 6.1 0.00018 20.9 0.8 4.1 4 0 0 4 4 4 3 EF hand EF-hand_9 PF14658.6 CBZ26223.1 - 2.6e-08 34.1 1.1 0.0021 18.4 0.1 3.0 2 2 1 3 3 3 2 EF-hand domain EF-hand_4 PF12763.7 CBZ26223.1 - 3.8e-05 23.6 1.7 0.018 15.0 0.1 2.4 1 1 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand Dockerin_1 PF00404.18 CBZ26223.1 - 0.0099 16.1 2.5 2.6 8.3 0.5 3.0 2 1 1 3 3 3 3 Dockerin type I domain Pkinase PF00069.25 CBZ26224.1 - 2e-57 194.6 0.0 2e-56 191.3 0.0 2.2 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ26224.1 - 2.5e-29 102.3 0.0 1.1e-28 100.3 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CBZ26224.1 - 0.0013 17.6 0.0 0.0024 16.7 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase PAS PF00989.25 CBZ26224.1 - 0.0017 18.3 0.0 0.0068 16.4 0.0 2.1 2 0 0 2 2 2 1 PAS fold PAS_9 PF13426.7 CBZ26224.1 - 0.0019 18.5 0.0 0.0049 17.1 0.0 1.7 1 0 0 1 1 1 1 PAS domain RIO1 PF01163.22 CBZ26224.1 - 0.004 16.8 0.0 0.03 13.9 0.0 2.2 2 0 0 2 2 2 1 RIO1 family FTA2 PF13095.6 CBZ26224.1 - 0.0082 15.8 0.0 0.015 15.0 0.0 1.4 1 0 0 1 1 1 1 Kinetochore Sim4 complex subunit FTA2 Kinase-like PF14531.6 CBZ26224.1 - 0.0086 15.4 0.0 0.044 13.1 0.0 1.9 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 CBZ26224.1 - 0.014 15.3 0.0 0.034 14.0 0.0 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.14 CBZ26224.1 - 0.049 13.0 0.1 0.11 11.8 0.1 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family PMP22_Claudin PF00822.20 CBZ26224.1 - 0.11 12.3 2.4 0.26 11.2 2.4 1.5 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin family CLP1_P PF16575.5 CBZ26227.1 - 1.3e-08 34.9 0.0 1.3e-07 31.6 0.0 2.1 1 1 0 1 1 1 1 mRNA cleavage and polyadenylation factor CLP1 P-loop Clp1 PF06807.14 CBZ26227.1 - 0.0016 18.9 0.0 0.0035 17.7 0.0 1.6 1 0 0 1 1 1 1 Pre-mRNA cleavage complex II protein Clp1 CLP1_N PF16573.5 CBZ26227.1 - 0.057 13.6 0.0 0.11 12.7 0.0 1.5 1 0 0 1 1 1 0 N-terminal beta-sandwich domain of polyadenylation factor FtsK_SpoIIIE PF01580.18 CBZ26227.1 - 0.067 12.5 0.0 0.11 11.9 0.0 1.2 1 0 0 1 1 1 0 FtsK/SpoIIIE family DUF498 PF04430.14 CBZ26228.1 - 3.5e-19 68.9 0.0 7e-19 67.9 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF498/DUF598) HA PF03457.14 CBZ26228.1 - 0.047 14.0 0.3 0.52 10.7 0.1 2.7 2 0 0 2 2 2 0 Helicase associated domain tRNA_int_endo PF01974.17 CBZ26229.1 - 2.6e-15 56.3 0.0 3.7e-15 55.7 0.0 1.2 1 0 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain Ribosomal_L34e PF01199.18 CBZ26230.1 - 8.4e-27 93.3 2.4 8.4e-27 93.3 2.4 2.2 2 1 0 2 2 2 1 Ribosomal protein L34e Ribosomal_S27e PF01667.17 CBZ26231.1 - 8.1e-22 76.7 3.2 9.9e-22 76.4 3.2 1.1 1 0 0 1 1 1 1 Ribosomal protein S27 FYVE_2 PF02318.16 CBZ26231.1 - 0.014 15.6 0.8 0.016 15.4 0.8 1.1 1 0 0 1 1 1 0 FYVE-type zinc finger Zn_Tnp_IS1595 PF12760.7 CBZ26231.1 - 0.025 14.5 1.8 0.04 13.9 1.8 1.5 1 0 0 1 1 1 0 Transposase zinc-ribbon domain zinc_ribbon_4 PF13717.6 CBZ26231.1 - 0.13 12.2 4.6 2.9 7.9 4.6 2.4 1 1 0 1 1 1 0 zinc-ribbon domain HypA PF01155.19 CBZ26231.1 - 0.15 12.1 1.8 0.17 11.9 1.8 1.2 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA OrfB_Zn_ribbon PF07282.11 CBZ26231.1 - 1.3 9.0 6.0 11 6.0 6.3 2.0 1 1 1 2 2 2 0 Putative transposase DNA-binding domain Ribosomal_L1 PF00687.21 CBZ26232.1 - 4.1e-41 141.0 2.5 5e-41 140.7 2.5 1.0 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family NAC PF01849.18 CBZ26233.1 - 1.2e-16 60.4 0.0 1.8e-16 59.9 0.0 1.3 1 0 0 1 1 1 1 NAC domain Carbam_trans_N PF02543.15 CBZ26233.1 - 0.065 12.9 0.0 0.078 12.6 0.0 1.2 1 0 0 1 1 1 0 Carbamoyltransferase N-terminus MORN PF02493.20 CBZ26234.1 - 3.3e-16 58.1 62.4 6.3e-05 22.6 1.2 9.4 10 0 0 10 10 10 7 MORN repeat DUF448 PF04296.13 CBZ26234.1 - 0.01 15.7 4.2 11 6.0 0.0 5.0 5 3 2 7 7 7 0 Protein of unknown function (DUF448) DUF2766 PF10964.8 CBZ26234.1 - 0.044 13.7 0.0 0.15 12.1 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2766) PilJ_C PF18223.1 CBZ26234.1 - 2.9 8.4 6.8 5.2 7.6 0.1 3.2 2 2 1 3 3 3 0 Pili PilJ C-terminal domain CH PF00307.31 CBZ26235.1 - 0.00025 21.2 0.0 0.00067 19.8 0.0 1.7 1 0 0 1 1 1 1 Calponin homology (CH) domain IMS PF00817.20 CBZ26235.1 - 0.0019 18.2 0.3 0.0044 17.0 0.3 1.5 1 0 0 1 1 1 1 impB/mucB/samB family DSBA PF01323.20 CBZ26235.1 - 0.01 15.7 2.2 0.029 14.1 2.2 1.8 1 0 0 1 1 1 0 DSBA-like thioredoxin domain RasGAP_C PF03836.15 CBZ26235.1 - 0.074 13.2 0.2 0.21 11.7 0.2 1.8 1 0 0 1 1 1 0 RasGAP C-terminus Tropomyosin_1 PF12718.7 CBZ26235.1 - 0.098 12.8 8.6 0.087 13.0 4.9 2.5 2 0 0 2 2 2 0 Tropomyosin like DASH_Spc19 PF08287.11 CBZ26235.1 - 0.11 12.4 13.6 1.2 9.0 1.1 3.0 2 0 0 2 2 2 0 Spc19 Sipho_Gp157 PF05565.11 CBZ26235.1 - 0.15 12.1 3.3 0.22 11.5 2.1 2.0 2 0 0 2 2 2 0 Siphovirus Gp157 KLRAQ PF10205.9 CBZ26235.1 - 0.16 12.2 4.5 0.45 10.8 4.5 1.8 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein DUF2710 PF10921.8 CBZ26235.1 - 0.69 10.4 4.4 1.4 9.4 0.2 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2710) BRE1 PF08647.11 CBZ26235.1 - 5.5 7.1 12.4 7.9 6.6 0.5 2.7 2 0 0 2 2 2 0 BRE1 E3 ubiquitin ligase GCV_T PF01571.21 CBZ26236.1 - 1.2e-76 257.5 0.3 1.5e-76 257.2 0.3 1.1 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.11 CBZ26236.1 - 1.5e-17 63.3 0.2 4.4e-17 61.8 0.2 1.8 1 0 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain Pico_P1A PF02226.16 CBZ26236.1 - 0.06 13.4 0.0 0.13 12.4 0.0 1.4 1 0 0 1 1 1 0 Picornavirus coat protein (VP4) GCV_T PF01571.21 CBZ26237.1 - 8.1e-80 267.9 0.5 9.9e-80 267.6 0.5 1.1 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.11 CBZ26237.1 - 9.6e-19 67.1 0.3 2.9e-18 65.6 0.1 1.8 2 0 0 2 2 2 1 Glycine cleavage T-protein C-terminal barrel domain Pico_P1A PF02226.16 CBZ26237.1 - 0.06 13.4 0.0 0.13 12.4 0.0 1.4 1 0 0 1 1 1 0 Picornavirus coat protein (VP4) TolA_bind_tri PF16331.5 CBZ26238.1 - 0.0042 17.1 1.1 0.0084 16.2 1.1 1.5 1 0 0 1 1 1 1 TolA binding protein trimerisation AIP3 PF03915.13 CBZ26238.1 - 0.0076 15.4 0.2 0.0083 15.3 0.2 1.1 1 0 0 1 1 1 1 Actin interacting protein 3 HisKA_3 PF07730.13 CBZ26238.1 - 0.031 14.8 0.7 0.06 13.9 0.7 1.5 1 0 0 1 1 1 0 Histidine kinase Uds1 PF15456.6 CBZ26238.1 - 0.075 13.2 3.2 0.1 12.8 3.2 1.1 1 0 0 1 1 1 0 Up-regulated During Septation Acyl-CoA_dh_2 PF08028.11 CBZ26238.1 - 0.08 13.2 2.1 0.87 9.9 0.1 2.0 1 1 1 2 2 2 0 Acyl-CoA dehydrogenase, C-terminal domain DUF1690 PF07956.11 CBZ26238.1 - 0.09 13.2 2.8 0.083 13.3 1.6 1.6 1 1 1 2 2 2 0 Protein of Unknown function (DUF1690) bZIP_2 PF07716.15 CBZ26238.1 - 0.57 10.3 7.1 2.8 8.1 2.7 2.3 2 0 0 2 2 2 0 Basic region leucine zipper HrpA_pilin PF09589.10 CBZ26238.1 - 0.8 10.4 4.1 1.6 9.5 2.0 2.1 1 1 1 2 2 2 0 HrpA pilus formation protein zf-C3HC4_3 PF13920.6 CBZ26239.1 - 3.6e-18 65.2 31.6 3.5e-13 49.2 11.8 4.4 4 1 1 5 5 5 2 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 CBZ26239.1 - 1e-05 25.3 9.9 1e-05 25.3 9.9 3.6 3 1 1 4 4 4 2 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 CBZ26239.1 - 0.00045 20.1 12.3 0.00045 20.1 12.3 3.9 4 0 0 4 4 4 2 zinc-RING finger domain zf-RING_2 PF13639.6 CBZ26239.1 - 0.0092 16.3 13.2 0.0092 16.3 13.2 4.6 5 0 0 5 5 5 2 Ring finger domain zf-C3HC4_2 PF13923.6 CBZ26239.1 - 0.27 11.1 36.6 0.36 10.7 13.8 3.5 3 1 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) ADK_lid PF05191.14 CBZ26239.1 - 0.44 10.6 0.0 0.44 10.6 0.0 4.4 4 2 0 4 4 4 0 Adenylate kinase, active site lid HGTP_anticodon PF03129.20 CBZ26240.1 - 4.3e-18 65.2 0.1 8.6e-18 64.3 0.1 1.5 1 0 0 1 1 1 1 Anticodon binding domain tRNA-synt_2b PF00587.25 CBZ26240.1 - 6e-07 29.6 0.0 3e-06 27.3 0.0 2.1 1 1 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Snf7 PF03357.21 CBZ26241.1 - 1.9e-29 102.5 31.0 1.9e-29 102.5 31.0 1.5 2 0 0 2 2 2 1 Snf7 SOG2 PF10428.9 CBZ26241.1 - 0.012 14.8 2.4 0.013 14.7 2.4 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein DASH_Dam1 PF08653.10 CBZ26241.1 - 5.4 6.9 7.1 0.77 9.6 0.7 2.7 3 0 0 3 3 3 0 DASH complex subunit Dam1 DUF4407 PF14362.6 CBZ26241.1 - 6 6.1 17.6 2.1 7.6 15.0 1.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) HAP2-GCS1 PF10699.9 CBZ26242.1 - 4.9e-14 52.0 0.0 4.9e-14 52.0 0.0 2.0 2 0 0 2 2 2 1 Male gamete fusion factor THOC7 PF05615.13 CBZ26243.1 - 0.016 15.4 2.1 0.031 14.6 2.1 1.3 1 0 0 1 1 1 0 Tho complex subunit 7 Gasdermin_C PF17708.1 CBZ26243.1 - 0.079 13.1 1.1 0.16 12.1 1.1 1.4 1 0 0 1 1 1 0 Gasdermin PUB domain WD40 PF00400.32 CBZ26244.1 - 1.5e-14 54.2 2.3 0.0004 21.1 0.0 5.4 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBZ26244.1 - 2.3e-09 37.5 0.0 1.3 9.4 0.0 5.1 3 2 2 5 5 5 5 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 CBZ26244.1 - 0.02 13.8 0.0 0.093 11.7 0.0 2.1 2 1 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein MAM33 PF02330.16 CBZ26245.1 - 0.00015 21.8 0.0 0.00097 19.1 0.0 1.9 1 1 0 2 2 2 1 Mitochondrial glycoprotein DUF3168 PF11367.8 CBZ26246.1 - 0.082 13.1 0.5 8.8 6.5 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3168) DUF982 PF06169.12 CBZ26246.1 - 0.085 12.9 1.1 0.2 11.7 1.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF982) AdoHcyase PF05221.17 CBZ26247.1 - 5.3e-131 436.2 0.0 1.4e-73 247.6 0.0 2.0 1 1 1 2 2 2 2 S-adenosyl-L-homocysteine hydrolase AdoHcyase_NAD PF00670.21 CBZ26247.1 - 2.9e-86 287.6 2.7 4.2e-86 287.0 2.7 1.2 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 2-Hacid_dh_C PF02826.19 CBZ26247.1 - 9.7e-10 38.1 0.0 2e-09 37.1 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IlvN PF07991.12 CBZ26247.1 - 0.00013 21.6 0.0 0.00021 20.9 0.0 1.4 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain TrkA_N PF02254.18 CBZ26247.1 - 0.00078 19.7 0.2 0.0039 17.4 0.1 2.3 2 1 0 2 2 2 1 TrkA-N domain NAD_binding_7 PF13241.6 CBZ26247.1 - 0.0017 18.7 0.1 0.0043 17.5 0.1 1.6 1 0 0 1 1 1 1 Putative NAD(P)-binding PALP PF00291.25 CBZ26247.1 - 0.046 13.1 0.5 0.13 11.6 0.2 1.8 2 0 0 2 2 2 0 Pyridoxal-phosphate dependent enzyme ELFV_dehydrog PF00208.21 CBZ26247.1 - 0.068 12.9 0.0 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase DUF2244 PF10003.9 CBZ26248.1 - 8.8 6.0 9.2 16 5.2 7.4 2.0 2 0 0 2 2 2 0 Integral membrane protein (DUF2244) Telomerase_RBD PF12009.8 CBZ26249.1 - 3.1e-21 75.9 0.0 5.7e-21 75.0 0.0 1.5 1 0 0 1 1 1 1 Telomerase ribonucleoprotein complex - RNA binding domain RVT_1 PF00078.27 CBZ26249.1 - 0.0016 18.0 0.0 0.0043 16.6 0.0 1.6 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) OmpH PF03938.14 CBZ26251.1 - 0.014 15.8 5.7 1.7 9.0 1.0 2.7 1 1 2 3 3 3 0 Outer membrane protein (OmpH-like) IFT46_B_C PF12317.8 CBZ26251.1 - 0.022 14.5 0.9 0.048 13.4 0.9 1.7 1 1 0 1 1 1 0 Intraflagellar transport complex B protein 46 C terminal Atg14 PF10186.9 CBZ26251.1 - 0.027 13.5 0.3 0.027 13.5 0.3 2.1 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 RACo_linker PF17650.1 CBZ26251.1 - 0.037 13.9 2.5 0.24 11.3 0.2 2.3 2 0 0 2 2 2 0 RACo linker region Hemagglutinin PF00509.18 CBZ26251.1 - 0.064 11.6 1.3 0.084 11.3 1.3 1.1 1 0 0 1 1 1 0 Haemagglutinin YkyA PF10368.9 CBZ26251.1 - 0.25 11.0 6.5 5.6 6.6 0.1 2.9 3 0 0 3 3 3 0 Putative cell-wall binding lipoprotein AAA_13 PF13166.6 CBZ26251.1 - 0.4 9.3 8.7 0.38 9.3 7.5 1.4 1 1 0 1 1 1 0 AAA domain TACC_C PF05010.14 CBZ26251.1 - 0.72 9.6 15.9 0.025 14.4 6.1 2.8 2 1 1 3 3 3 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal TFIIF_beta_N PF17683.1 CBZ26251.1 - 1.1 9.9 5.2 25 5.5 5.2 2.2 1 1 0 1 1 1 0 TFIIF, beta subunit N-terminus Fez1 PF06818.15 CBZ26251.1 - 1.2 9.5 13.9 0.15 12.5 7.8 2.1 1 1 1 2 2 2 0 Fez1 DUF1664 PF07889.12 CBZ26251.1 - 1.6 8.8 10.1 0.35 10.9 1.2 3.1 2 1 2 4 4 4 0 Protein of unknown function (DUF1664) TPR_MLP1_2 PF07926.12 CBZ26251.1 - 6 6.9 15.3 2.8 8.0 5.9 3.1 3 0 0 3 3 3 0 TPR/MLP1/MLP2-like protein CDC73_C PF05179.14 CBZ26254.1 - 6.7e-33 113.6 0.0 9.4e-33 113.1 0.0 1.2 1 0 0 1 1 1 1 RNA pol II accessory factor, Cdc73 family, C-terminal DEAD PF00270.29 CBZ26254.1 - 0.12 12.1 0.0 0.18 11.5 0.0 1.2 1 0 0 1 1 1 0 DEAD/DEAH box helicase Proteasome PF00227.26 CBZ26255.1 - 8.7e-25 87.3 0.3 3.3e-24 85.4 0.3 1.7 1 1 0 1 1 1 1 Proteasome subunit Fimbrial_PilY2 PF14481.6 CBZ26255.1 - 0.15 11.7 0.0 0.34 10.6 0.0 1.6 1 0 0 1 1 1 0 Type 4 fimbrial biogenesis protein PilY2 NTP_transf_2 PF01909.23 CBZ26256.1 - 5.8e-07 29.7 0.0 1e-06 28.9 0.0 1.3 1 0 0 1 1 1 1 Nucleotidyltransferase domain Polbeta PF18765.1 CBZ26256.1 - 0.00059 19.9 0.0 0.0011 19.1 0.0 1.3 1 0 0 1 1 1 1 Polymerase beta, Nucleotidyltransferase Rieske PF00355.26 CBZ26257.1 - 0.0024 17.8 0.0 0.0036 17.2 0.0 1.4 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain V-SNARE_C PF12352.8 CBZ26259.1 - 2e-06 27.9 1.0 2e-06 27.9 1.0 1.8 2 0 0 2 2 2 1 Snare region anchored in the vesicle membrane C-terminus SSFA2_C PF14723.6 CBZ26259.1 - 0.052 13.4 0.1 0.052 13.4 0.1 2.1 2 0 0 2 2 2 0 Sperm-specific antigen 2 C-terminus LemA PF04011.12 CBZ26259.1 - 0.095 12.5 0.3 10 5.9 0.0 2.4 2 0 0 2 2 2 0 LemA family Peptidase_M14 PF00246.24 CBZ26260.1 - 1.6e-13 51.1 0.0 8e-13 48.8 0.0 1.9 1 1 0 1 1 1 1 Zinc carboxypeptidase AstE_AspA PF04952.14 CBZ26260.1 - 8.1e-07 28.4 0.1 1.3e-06 27.7 0.1 1.3 1 0 0 1 1 1 1 Succinylglutamate desuccinylase / Aspartoacylase family Pepdidase_M14_N PF18027.1 CBZ26260.1 - 1.6e-06 28.5 0.0 3e-06 27.5 0.0 1.4 1 0 0 1 1 1 1 Cytosolic carboxypeptidase N-terminal domain SSP160 PF06933.11 CBZ26260.1 - 1.6 6.8 10.4 0.012 13.8 1.7 1.8 2 0 0 2 2 2 0 Special lobe-specific silk protein SSP160 TPR_16 PF13432.6 CBZ26261.1 - 0.0021 18.7 12.1 0.26 12.0 0.6 3.9 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.17 CBZ26261.1 - 0.005 16.9 13.2 0.61 10.3 0.4 4.4 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_12 PF13424.6 CBZ26261.1 - 0.0051 17.1 14.5 0.045 14.0 0.4 4.2 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_1 PF00515.28 CBZ26261.1 - 0.0081 15.9 4.0 4.9 7.1 0.2 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat DUF913 PF06025.12 CBZ26261.1 - 0.078 12.0 2.2 0.12 11.3 2.2 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) TPR_7 PF13176.6 CBZ26261.1 - 0.24 11.5 9.3 2.5 8.3 0.7 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat Strep_SA_rep PF06696.11 CBZ26261.1 - 2.3 8.3 9.6 3 7.9 3.8 2.7 2 0 0 2 2 2 0 Streptococcal surface antigen repeat TatD_DNase PF01026.21 CBZ26262.1 - 2.5e-27 95.9 0.1 1.3e-26 93.5 0.0 1.9 2 0 0 2 2 2 1 TatD related DNase RCC1 PF00415.18 CBZ26263.1 - 2.2e-39 133.8 10.3 2.6e-09 37.5 0.1 7.3 7 0 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 CBZ26263.1 - 2.2e-19 68.7 25.1 1.1e-07 31.4 3.0 7.5 7 1 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat GRA6 PF05084.13 CBZ26263.1 - 1.6 8.6 9.2 6 6.8 1.4 2.4 2 0 0 2 2 2 0 Granule antigen protein (GRA6) BLOC1S3 PF15753.5 CBZ26263.1 - 3.1 7.9 5.9 9.7 6.3 0.2 2.3 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex 1 subunit 3 His_Phos_1 PF00300.22 CBZ26264.1 - 6.1e-13 48.9 4.2 4.4e-05 23.3 0.1 3.5 1 1 2 4 4 4 3 Histidine phosphatase superfamily (branch 1) DUF501 PF04417.12 CBZ26264.1 - 0.018 14.8 0.3 0.031 14.1 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF501) CREPT PF16566.5 CBZ26264.1 - 0.05 13.8 1.7 0.095 12.9 1.7 1.4 1 0 0 1 1 1 0 Cell-cycle alteration and expression-elevated protein in tumour IQ PF00612.27 CBZ26265.1 - 2.2e-13 48.7 12.1 8.1e-05 22.1 0.6 3.8 3 0 0 3 3 3 3 IQ calmodulin-binding motif Glyco_hydro_31 PF01055.26 CBZ26267.1 - 1.3e-50 172.9 0.0 2.1e-50 172.2 0.0 1.4 1 1 0 1 1 1 1 Glycosyl hydrolases family 31 Tnp_22_dsRBD PF17490.2 CBZ26268.1 - 0.12 12.4 0.1 0.25 11.4 0.1 1.5 1 0 0 1 1 1 0 L1 transposable element dsRBD-like domain Amastin PF07344.11 CBZ26270.1 - 1.4e-05 25.0 6.2 1.4e-05 25.0 6.2 1.9 2 0 0 2 2 2 1 Amastin surface glycoprotein Amastin PF07344.11 CBZ26271.1 - 1.7e-13 50.7 4.9 2.8e-13 50.0 4.9 1.3 1 1 0 1 1 1 1 Amastin surface glycoprotein PMP22_Claudin PF00822.20 CBZ26271.1 - 0.023 14.6 7.9 0.044 13.7 7.9 1.6 1 1 0 1 1 1 0 PMP-22/EMP/MP20/Claudin family DUF3433 PF11915.8 CBZ26271.1 - 0.29 11.6 0.0 0.29 11.6 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3433) OAD_gamma PF04277.13 CBZ26271.1 - 2.3 8.9 5.9 2.1 9.0 1.6 2.5 2 0 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain TFIIS_C PF01096.18 CBZ26272.1 - 5.8e-11 42.1 8.4 5.8e-11 42.1 8.4 2.5 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) DUF1451 PF07295.11 CBZ26272.1 - 0.027 14.5 0.3 0.027 14.5 0.3 2.5 4 0 0 4 4 4 0 Zinc-ribbon containing domain RNA_POL_M_15KD PF02150.16 CBZ26272.1 - 0.11 12.4 5.1 12 5.8 0.1 3.4 3 0 0 3 3 3 0 RNA polymerases M/15 Kd subunit Baculo_LEF5_C PF11792.8 CBZ26272.1 - 0.73 9.6 6.8 0.086 12.5 2.0 2.0 2 1 0 2 2 2 0 Baculoviridae late expression factor 5 C-terminal domain HypA PF01155.19 CBZ26272.1 - 1.2 9.2 8.3 0.88 9.6 0.2 2.6 2 1 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Elf1 PF05129.13 CBZ26272.1 - 1.4 9.0 0.0 1.4 9.0 0.0 3.3 3 2 1 4 4 4 0 Transcription elongation factor Elf1 like Katanin_con80 PF13925.6 CBZ26273.1 - 0.0048 16.9 3.3 0.032 14.3 1.8 2.5 2 1 0 2 2 2 1 con80 domain of Katanin Phage_lysozyme PF00959.19 CBZ26273.1 - 0.045 14.2 0.0 0.17 12.3 0.0 2.1 1 0 0 1 1 1 0 Phage lysozyme ADH_zinc_N PF00107.26 CBZ26275.1 - 6.5e-30 103.8 0.4 1.2e-29 102.9 0.0 1.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 CBZ26275.1 - 8.6e-18 65.7 0.0 2.1e-17 64.4 0.0 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 CBZ26275.1 - 1.3e-12 47.5 0.2 5e-12 45.7 0.2 2.0 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Semialdhyde_dh PF01118.24 CBZ26275.1 - 0.015 15.7 0.1 0.66 10.4 0.0 2.4 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain Cpn10 PF00166.21 CBZ26275.1 - 0.016 15.2 0.3 0.43 10.7 0.0 2.6 2 0 0 2 2 2 0 Chaperonin 10 Kd subunit TrkA_N PF02254.18 CBZ26275.1 - 0.022 15.0 0.0 0.044 14.0 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain Glycos_transf_4 PF00953.21 CBZ26276.1 - 2.7e-48 164.0 6.5 2.7e-48 164.0 6.5 2.1 2 0 0 2 2 2 1 Glycosyl transferase family 4 Seadorna_Vp10 PF07322.11 CBZ26276.1 - 0.1 12.0 0.0 0.2 11.0 0.0 1.4 1 0 0 1 1 1 0 Seadornavirus Vp10 FA_desaturase PF00487.24 CBZ26276.1 - 2.5 7.8 8.5 3.1 7.6 0.2 2.8 2 1 1 3 3 3 0 Fatty acid desaturase Sld5 PF05916.11 CBZ26277.1 - 4.6e-19 68.9 0.0 9.6e-19 67.9 0.0 1.5 2 0 0 2 2 2 1 GINS complex protein Arrestin_N PF00339.29 CBZ26278.1 - 3.9e-07 30.2 0.0 2.4e-05 24.4 0.0 3.1 2 1 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain Spo0M PF07070.11 CBZ26278.1 - 5.1e-05 22.9 0.1 0.00019 21.1 0.2 1.9 2 0 0 2 2 2 1 SpoOM protein LDB19 PF13002.7 CBZ26278.1 - 8.3e-05 22.4 0.1 0.00042 20.1 0.0 2.1 3 0 0 3 3 3 1 Arrestin_N terminal like RraB PF06877.11 CBZ26278.1 - 0.025 15.3 0.1 0.062 14.0 0.1 1.6 1 0 0 1 1 1 0 Regulator of ribonuclease activity B Arrestin_C PF02752.22 CBZ26278.1 - 0.18 12.3 0.2 0.49 10.8 0.1 1.8 2 0 0 2 2 2 0 Arrestin (or S-antigen), C-terminal domain Utp21 PF04192.12 CBZ26279.1 - 2.3e-23 82.9 0.0 3.6e-23 82.3 0.0 1.3 1 0 0 1 1 1 1 Utp21 specific WD40 associated putative domain WD40 PF00400.32 CBZ26279.1 - 6.8e-14 52.0 9.4 0.0011 19.8 0.0 8.8 10 0 0 10 10 10 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBZ26279.1 - 6.3e-13 48.8 0.2 0.00014 22.1 0.0 5.2 4 2 1 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain PQQ_2 PF13360.6 CBZ26279.1 - 4.8e-07 29.6 2.7 0.0006 19.5 0.2 3.2 2 2 1 3 3 3 3 PQQ-like domain Nup160 PF11715.8 CBZ26279.1 - 0.00031 19.5 0.6 0.037 12.7 0.0 3.6 3 1 0 3 3 3 1 Nucleoporin Nup120/160 PALB2_WD40 PF16756.5 CBZ26279.1 - 0.00055 19.0 5.4 0.042 12.8 0.1 3.8 3 1 1 4 4 4 2 Partner and localizer of BRCA2 WD40 domain Hira PF07569.11 CBZ26279.1 - 0.032 14.0 0.3 6.8 6.4 0.1 3.7 3 1 1 4 4 4 0 TUP1-like enhancer of split Utp12 PF04003.12 CBZ26279.1 - 0.033 14.5 0.0 0.069 13.5 0.0 1.5 1 0 0 1 1 1 0 Dip2/Utp12 Family HU-CCDC81_euk_2 PF18289.1 CBZ26279.1 - 0.18 12.0 0.0 2.9 8.1 0.0 2.4 2 0 0 2 2 2 0 CCDC81 eukaryotic HU domain 2 LRR_6 PF13516.6 CBZ26281.1 - 5.8e-40 132.0 47.3 0.0004 20.2 0.1 18.6 19 0 0 19 19 19 12 Leucine Rich repeat LRR_4 PF12799.7 CBZ26281.1 - 1.1e-14 54.2 28.9 0.0029 18.0 0.0 12.2 11 2 0 11 11 11 6 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 CBZ26281.1 - 4.8e-08 32.5 16.8 59 4.8 0.0 15.3 18 0 0 18 18 18 0 Leucine Rich Repeat LRR_8 PF13855.6 CBZ26281.1 - 0.0014 18.4 40.2 0.12 12.2 0.4 12.6 8 5 5 13 13 13 3 Leucine rich repeat WD40 PF00400.32 CBZ26282.1 - 3.8e-05 24.4 2.0 8.5 7.4 0.1 5.4 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBZ26282.1 - 0.023 15.0 0.0 5.7 7.3 0.0 3.2 4 0 0 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain Pkinase PF00069.25 CBZ26283.1 - 2.5e-47 161.5 0.0 2.7e-24 85.9 0.0 2.7 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ26283.1 - 1.3e-18 67.2 0.0 1.7e-11 43.9 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 CBZ26283.1 - 0.011 15.1 0.0 1.3 8.3 0.0 2.9 3 0 0 3 3 3 0 Kinase-like APH PF01636.23 CBZ26283.1 - 0.038 13.9 0.9 0.15 11.9 0.1 2.3 2 1 1 3 3 3 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 CBZ26283.1 - 0.14 10.9 0.0 0.22 10.3 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Phage_hub_GP28 PF11110.8 CBZ26283.1 - 0.23 11.3 0.0 0.41 10.5 0.0 1.3 1 0 0 1 1 1 0 Baseplate hub distal subunit DUF389 PF04087.14 CBZ26285.1 - 7.4 6.6 8.1 6.1 6.9 0.8 2.7 1 1 1 2 2 2 0 Domain of unknown function (DUF389) TPR_14 PF13428.6 CBZ26286.1 - 5.3e-09 36.2 56.0 0.035 14.9 1.3 12.9 9 3 5 14 14 14 6 Tetratricopeptide repeat HAT PF02184.16 CBZ26286.1 - 1.3e-06 28.3 17.0 0.11 12.5 0.2 5.8 6 0 0 6 6 6 3 HAT (Half-A-TPR) repeat TPR_19 PF14559.6 CBZ26286.1 - 5.2e-05 23.7 20.4 0.0024 18.3 0.2 6.2 7 0 0 7 7 7 2 Tetratricopeptide repeat DUF2063 PF09836.9 CBZ26286.1 - 0.002 18.3 1.1 0.0055 16.9 0.3 2.2 2 0 0 2 2 2 1 Putative DNA-binding domain Mad3_BUB1_I PF08311.12 CBZ26286.1 - 0.0092 16.0 3.1 4.8 7.2 0.1 5.1 4 2 0 4 4 4 1 Mad3/BUB1 homology region 1 NRDE-2 PF08424.10 CBZ26286.1 - 0.011 14.9 1.6 0.15 11.2 0.4 2.8 2 0 0 2 2 2 0 NRDE-2, necessary for RNA interference TPR_9 PF13371.6 CBZ26286.1 - 0.018 15.2 0.6 0.018 15.2 0.6 6.1 7 1 0 7 7 7 0 Tetratricopeptide repeat CCP_MauG PF03150.14 CBZ26286.1 - 0.078 13.6 2.2 0.31 11.7 0.0 2.9 3 1 0 3 3 3 0 Di-haem cytochrome c peroxidase Arf PF00025.21 CBZ26287.1 - 1.1e-11 44.5 0.0 2e-11 43.6 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family PH PF00169.29 CBZ26287.1 - 2.1e-08 34.6 0.1 4.9e-08 33.4 0.1 1.6 1 0 0 1 1 1 1 PH domain PH_8 PF15409.6 CBZ26287.1 - 0.028 14.7 0.2 0.14 12.5 0.2 2.3 2 0 0 2 2 2 0 Pleckstrin homology domain MMR_HSR1 PF01926.23 CBZ26287.1 - 0.11 12.5 0.0 0.54 10.4 0.0 2.2 2 1 0 2 2 2 0 50S ribosome-binding GTPase CHAP PF05257.16 CBZ26288.1 - 2.7e-11 43.9 0.1 7.9e-11 42.4 0.1 1.9 1 0 0 1 1 1 1 CHAP domain SET PF00856.28 CBZ26289.1 - 5.2e-08 33.4 0.0 2.9e-07 31.0 0.0 2.1 1 1 0 1 1 1 1 SET domain DUF3618 PF12277.8 CBZ26289.1 - 2.5 8.4 5.1 11 6.4 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3618) C2 PF00168.30 CBZ26290.1 - 2e-47 159.7 0.0 1.9e-11 44.2 0.0 8.3 8 1 0 8 8 8 6 C2 domain CEP76-C2 PF15627.6 CBZ26290.1 - 0.0022 17.6 0.2 0.17 11.4 0.0 3.0 3 0 0 3 3 3 1 CEP76 C2 domain C2 PF00168.30 CBZ26291.1 - 1e-20 73.9 0.0 2.3e-05 24.6 0.0 4.5 4 0 0 4 4 4 4 C2 domain CCD PF07860.11 CBZ26292.1 - 4.9 7.2 10.7 6.4 6.8 0.3 3.3 2 1 1 3 3 3 0 WisP family C-Terminal Region AAA PF00004.29 CBZ26294.1 - 6.5e-44 149.6 0.0 1.4e-43 148.5 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 CBZ26294.1 - 6.4e-15 54.7 0.3 2e-14 53.1 0.1 2.0 2 0 0 2 2 1 1 AAA+ lid domain AAA_5 PF07728.14 CBZ26294.1 - 2.9e-07 30.6 0.0 1.1e-06 28.7 0.0 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) Prot_ATP_ID_OB PF16450.5 CBZ26294.1 - 4.5e-07 29.7 0.7 1e-06 28.6 0.7 1.6 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_2 PF07724.14 CBZ26294.1 - 9.5e-07 29.1 0.0 2.4e-06 27.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 CBZ26294.1 - 2.5e-06 28.0 0.2 0.0001 22.8 0.0 2.7 2 1 1 3 3 3 1 AAA ATPase domain AAA_22 PF13401.6 CBZ26294.1 - 1.9e-05 25.0 2.4 0.0093 16.2 0.0 3.2 2 1 1 3 3 3 1 AAA domain RuvB_N PF05496.12 CBZ26294.1 - 2.1e-05 24.3 0.0 5.4e-05 23.0 0.0 1.8 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_18 PF13238.6 CBZ26294.1 - 0.00039 21.0 0.2 0.022 15.3 0.0 2.8 3 1 0 3 3 2 1 AAA domain IstB_IS21 PF01695.17 CBZ26294.1 - 0.0013 18.5 0.0 0.0037 17.0 0.0 1.7 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_33 PF13671.6 CBZ26294.1 - 0.0016 18.6 0.0 0.0037 17.4 0.0 1.8 1 1 0 1 1 1 1 AAA domain TIP49 PF06068.13 CBZ26294.1 - 0.0029 16.9 0.0 0.013 14.8 0.0 2.0 2 0 0 2 2 2 1 TIP49 P-loop domain ATPase PF06745.13 CBZ26294.1 - 0.003 16.9 0.2 0.1 11.9 0.0 2.6 3 0 0 3 3 3 1 KaiC AAA_28 PF13521.6 CBZ26294.1 - 0.0053 17.0 0.2 0.016 15.5 0.0 1.8 2 0 0 2 2 2 1 AAA domain NB-ARC PF00931.22 CBZ26294.1 - 0.0077 15.4 0.0 0.41 9.8 0.0 2.4 2 0 0 2 2 2 1 NB-ARC domain AAA_3 PF07726.11 CBZ26294.1 - 0.0078 16.1 0.0 0.018 14.9 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 CBZ26294.1 - 0.0081 15.9 0.9 0.055 13.2 0.1 2.9 2 1 0 2 2 2 1 Sigma-54 interaction domain Mg_chelatase PF01078.21 CBZ26294.1 - 0.0082 15.6 0.0 0.028 13.8 0.0 1.8 2 0 0 2 2 1 1 Magnesium chelatase, subunit ChlI AAA_25 PF13481.6 CBZ26294.1 - 0.0092 15.6 0.3 0.17 11.4 0.0 2.7 3 0 0 3 3 3 1 AAA domain RNA_helicase PF00910.22 CBZ26294.1 - 0.012 15.9 0.0 0.026 14.9 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_7 PF12775.7 CBZ26294.1 - 0.018 14.6 0.0 0.035 13.6 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region TsaE PF02367.17 CBZ26294.1 - 0.02 14.9 0.0 0.038 14.0 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_14 PF13173.6 CBZ26294.1 - 0.021 14.9 0.0 0.069 13.2 0.0 1.9 2 0 0 2 2 2 0 AAA domain ADIP PF11559.8 CBZ26294.1 - 0.022 14.8 1.4 0.045 13.8 1.4 1.4 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding DUF815 PF05673.13 CBZ26294.1 - 0.023 13.8 0.1 0.066 12.4 0.0 1.8 2 1 0 2 2 2 0 Protein of unknown function (DUF815) APG6_N PF17675.1 CBZ26294.1 - 0.024 15.2 0.2 0.05 14.1 0.2 1.5 1 0 0 1 1 1 0 Apg6 coiled-coil region AAA_24 PF13479.6 CBZ26294.1 - 0.025 14.3 0.1 0.066 12.9 0.1 1.9 1 1 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 CBZ26294.1 - 0.025 13.9 0.5 0.16 11.2 0.0 2.2 2 0 0 2 2 2 0 Zeta toxin AAA_11 PF13086.6 CBZ26294.1 - 0.028 14.2 0.1 0.33 10.7 0.0 2.2 2 0 0 2 2 2 0 AAA domain PhoH PF02562.16 CBZ26294.1 - 0.029 13.8 0.1 0.11 11.9 0.0 2.0 2 0 0 2 2 2 0 PhoH-like protein Parvo_NS1 PF01057.17 CBZ26294.1 - 0.048 12.7 0.0 0.085 11.9 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 DUF4618 PF15397.6 CBZ26294.1 - 0.063 12.7 1.0 0.17 11.3 1.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4618) AAA_19 PF13245.6 CBZ26294.1 - 0.075 13.4 2.6 0.65 10.3 0.0 2.8 2 1 1 3 3 3 0 AAA domain DUF2968 PF11180.8 CBZ26294.1 - 0.48 10.0 3.3 0.36 10.5 1.7 1.6 2 0 0 2 2 1 0 Protein of unknown function (DUF2968) HECT PF00632.25 CBZ26295.1 - 3.3e-59 200.9 0.0 4.7e-59 200.4 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) AOX PF01786.17 CBZ26296.1 - 4.4e-79 265.0 0.0 5.4e-79 264.7 0.0 1.1 1 0 0 1 1 1 1 Alternative oxidase GCP_C_terminal PF04130.13 CBZ26297.1 - 4.5e-42 144.6 0.1 9.8e-42 143.5 0.1 1.6 1 0 0 1 1 1 1 Gamma tubulin complex component C-terminal GCP_N_terminal PF17681.1 CBZ26297.1 - 1.5e-24 87.2 0.0 4.3e-24 85.7 0.0 1.8 1 1 0 1 1 1 1 Gamma tubulin complex component N-terminal DUF309 PF03745.14 CBZ26297.1 - 0.017 14.8 0.3 0.12 12.1 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF309) DEAD PF00270.29 CBZ26298.1 - 1.4e-31 109.6 0.2 9.5e-31 106.9 0.0 2.5 2 1 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CBZ26298.1 - 1.8e-30 105.5 0.4 1e-28 99.9 0.1 2.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 CBZ26298.1 - 0.00044 20.3 0.5 0.0039 17.2 0.0 2.9 3 1 0 3 3 3 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 CBZ26298.1 - 0.055 13.7 2.8 9.8 6.4 0.0 3.9 4 1 1 5 5 5 0 AAA domain Z1 PF10593.9 CBZ26298.1 - 0.12 11.9 1.9 0.2 11.2 0.1 2.2 2 0 0 2 2 2 0 Z1 domain Ribosomal_L22e PF01776.17 CBZ26300.1 - 3.1e-36 124.1 3.7 3.9e-36 123.7 3.7 1.1 1 0 0 1 1 1 1 Ribosomal L22e protein family Asparaginase PF00710.20 CBZ26301.1 - 1.2e-35 122.9 0.0 1.6e-35 122.4 0.0 1.2 1 0 0 1 1 1 1 Asparaginase, N-terminal Asparaginase_C PF17763.1 CBZ26301.1 - 1e-24 87.0 0.0 2.1e-24 86.0 0.0 1.5 2 0 0 2 2 2 1 Glutaminase/Asparaginase C-terminal domain TPR_19 PF14559.6 CBZ26302.1 - 2.6e-05 24.6 0.1 0.0073 16.8 0.1 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_17 PF13431.6 CBZ26302.1 - 0.00036 20.7 6.9 0.0018 18.5 0.7 3.7 5 0 0 5 5 5 1 Tetratricopeptide repeat ANAPC3 PF12895.7 CBZ26302.1 - 0.0015 18.7 1.4 0.17 12.1 0.1 3.3 3 0 0 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_2 PF07719.17 CBZ26302.1 - 0.0021 18.1 0.2 0.0021 18.1 0.2 2.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 CBZ26302.1 - 0.0025 18.5 1.8 2.9 8.9 0.4 3.2 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 CBZ26302.1 - 0.003 17.7 0.6 0.014 15.5 0.2 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.28 CBZ26302.1 - 0.0081 15.9 1.7 0.046 13.6 0.3 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.6 CBZ26302.1 - 0.016 14.9 0.5 0.075 12.7 0.2 2.4 3 0 0 3 3 3 0 TPR repeat TPR_16 PF13432.6 CBZ26302.1 - 0.031 14.9 0.5 0.18 12.5 0.1 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_4 PF07721.14 CBZ26302.1 - 0.034 14.8 0.8 0.12 13.0 0.8 2.0 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_12 PF13424.6 CBZ26302.1 - 0.071 13.4 0.1 0.2 12.0 0.1 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_10 PF13374.6 CBZ26302.1 - 0.16 11.9 0.3 0.54 10.2 0.3 1.9 1 0 0 1 1 1 0 Tetratricopeptide repeat Peptidase_M3 PF01432.20 CBZ26303.1 - 2.4e-72 244.7 0.1 7.6e-58 196.9 0.2 2.0 2 0 0 2 2 2 2 Peptidase family M3 Peptidase_M32 PF02074.15 CBZ26303.1 - 0.0045 15.8 0.3 0.0083 14.9 0.3 1.3 1 0 0 1 1 1 1 Carboxypeptidase Taq (M32) metallopeptidase DnaJ PF00226.31 CBZ26305.1 - 1.1e-23 83.1 0.1 2.8e-23 81.8 0.1 1.7 1 0 0 1 1 1 1 DnaJ domain DUF4817 PF16087.5 CBZ26305.1 - 0.074 12.9 0.0 0.31 10.9 0.0 2.0 2 0 0 2 2 2 0 Helix-turn-helix domain (DUF4817) Aa_trans PF01490.18 CBZ26306.1 - 6.3e-45 153.6 2.4 4.7e-37 127.7 0.0 2.6 2 1 0 2 2 2 2 Transmembrane amino acid transporter protein MTS PF05175.14 CBZ26307.1 - 2e-11 43.7 0.0 1.1e-08 34.8 0.0 2.3 2 0 0 2 2 2 2 Methyltransferase small domain Methyltransf_31 PF13847.6 CBZ26307.1 - 1.3e-08 34.8 0.0 3.5e-08 33.4 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CBZ26307.1 - 9.2e-08 32.7 0.0 5.2e-07 30.3 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain PrmA PF06325.13 CBZ26307.1 - 6.3e-07 29.1 0.0 1.3e-06 28.1 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Ubie_methyltran PF01209.18 CBZ26307.1 - 0.00015 21.2 0.0 0.00025 20.5 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Met_10 PF02475.16 CBZ26307.1 - 0.0014 18.4 0.0 0.0023 17.7 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_11 PF08241.12 CBZ26307.1 - 0.0016 19.1 0.0 0.0066 17.1 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 CBZ26307.1 - 0.0093 15.8 0.0 0.019 14.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CBZ26307.1 - 0.016 16.0 0.0 0.052 14.3 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_18 PF12847.7 CBZ26307.1 - 0.016 15.2 0.0 0.049 13.6 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_15 PF09445.10 CBZ26307.1 - 0.018 14.7 0.0 0.033 13.8 0.0 1.3 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase Methyltransf_16 PF10294.9 CBZ26307.1 - 0.028 14.2 0.0 0.048 13.4 0.0 1.3 1 0 0 1 1 1 0 Lysine methyltransferase Cons_hypoth95 PF03602.15 CBZ26307.1 - 0.065 12.9 0.1 0.45 10.1 0.0 2.0 1 1 1 2 2 2 0 Conserved hypothetical protein 95 Methyltransf_32 PF13679.6 CBZ26307.1 - 0.13 12.3 0.0 0.21 11.5 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain DUF2870 PF11069.8 CBZ26308.1 - 1.1e-35 121.9 0.1 2.2e-35 120.9 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2870) Ribosomal_L18 PF17135.4 CBZ26309.1 - 1.9e-74 249.1 3.7 2.1e-74 249.0 3.7 1.0 1 0 0 1 1 1 1 Ribosomal protein 60S L18 and 50S L18e Ribosomal_L27A PF00828.19 CBZ26309.1 - 0.0001 23.0 0.1 0.00034 21.3 0.1 1.9 1 1 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A Alpha_kinase PF02816.18 CBZ26312.1 - 4e-50 170.5 0.1 5.1e-50 170.2 0.1 1.1 1 0 0 1 1 1 1 Alpha-kinase family Alpha_E3_glycop PF01563.16 CBZ26312.1 - 0.16 12.1 0.0 0.45 10.6 0.0 1.7 1 0 0 1 1 1 0 Alphavirus E3 glycoprotein Alpha_kinase PF02816.18 CBZ26313.1 - 4.6e-72 242.0 0.0 5.4e-41 140.7 0.0 3.2 3 0 0 3 3 3 3 Alpha-kinase family SpdB PF05122.13 CBZ26313.1 - 0.4 10.8 0.1 0.4 10.8 0.1 3.7 4 0 0 4 4 4 0 Mobile element transfer protein Alpha_kinase PF02816.18 CBZ26314.1 - 1.4e-56 191.6 0.3 1.7e-56 191.3 0.3 1.1 1 0 0 1 1 1 1 Alpha-kinase family PSP1 PF04468.12 CBZ26315.1 - 1.9e-27 95.4 1.1 1.9e-27 95.4 1.1 1.7 2 0 0 2 2 2 1 PSP1 C-terminal conserved region DASH_Spc34 PF08657.10 CBZ26315.1 - 0.028 14.2 0.1 0.051 13.4 0.1 1.3 1 0 0 1 1 1 0 DASH complex subunit Spc34 BBS2_N PF14781.6 CBZ26317.1 - 0.09 12.7 0.0 0.82 9.6 0.0 2.4 2 0 0 2 2 2 0 Ciliary BBSome complex subunit 2, N-terminal zf-HC5HC2H PF13771.6 CBZ26318.1 - 8.9e-08 32.3 9.6 8.9e-08 32.3 9.6 3.6 5 0 0 5 5 5 1 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.6 CBZ26318.1 - 9.5e-06 25.7 12.0 9.5e-06 25.7 12.0 3.3 3 2 0 3 3 3 1 PHD-zinc-finger like domain PHD_2 PF13831.6 CBZ26318.1 - 6.3e-05 22.4 0.7 6.3e-05 22.4 0.7 3.2 3 0 0 3 3 3 1 PHD-finger EPL1 PF10513.9 CBZ26318.1 - 0.16 12.3 0.0 0.32 11.4 0.0 1.4 1 0 0 1 1 1 0 Enhancer of polycomb-like MGC-24 PF05283.11 CBZ26318.1 - 1.6 9.2 9.7 5.7 7.4 9.7 1.9 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin Transmemb_17 PF09799.9 CBZ26319.1 - 9e-17 61.6 11.6 1.2e-16 61.2 11.6 1.2 1 0 0 1 1 1 1 Predicted membrane protein DUF3930 PF13067.6 CBZ26319.1 - 0.041 14.1 0.5 7.5 6.9 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3930) FliJ PF02050.16 CBZ26320.1 - 1.5 9.0 12.9 16 5.8 0.1 2.6 2 0 0 2 2 2 0 Flagellar FliJ protein Ham1p_like PF01725.16 CBZ26322.1 - 1.1e-46 159.2 0.0 1.2e-46 159.0 0.0 1.0 1 0 0 1 1 1 1 Ham1 family Abhydrolase_2 PF02230.16 CBZ26323.1 - 7.4e-09 35.7 0.0 5.2e-07 29.7 0.0 2.4 2 0 0 2 2 2 1 Phospholipase/Carboxylesterase Peptidase_S9 PF00326.21 CBZ26323.1 - 1.1e-08 34.8 0.6 1.7e-06 27.7 0.1 2.9 1 1 2 3 3 3 1 Prolyl oligopeptidase family Esterase_phd PF10503.9 CBZ26323.1 - 2.9e-07 30.2 2.5 2.2e-06 27.4 2.5 2.3 1 1 0 1 1 1 1 Esterase PHB depolymerase Esterase PF00756.20 CBZ26323.1 - 1.6e-05 24.6 0.2 0.00016 21.5 0.2 2.1 1 1 0 1 1 1 1 Putative esterase FSH1 PF03959.13 CBZ26323.1 - 0.0004 20.1 0.0 0.0011 18.7 0.0 1.7 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Hydrolase_4 PF12146.8 CBZ26323.1 - 0.0004 19.7 0.5 2.7 7.2 0.1 3.2 2 1 1 3 3 3 2 Serine aminopeptidase, S33 Abhydrolase_3 PF07859.13 CBZ26323.1 - 0.0046 16.8 0.1 0.015 15.2 0.1 1.8 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_1 PF00561.20 CBZ26323.1 - 0.019 14.7 0.1 0.31 10.7 0.0 2.3 1 1 1 2 2 2 0 alpha/beta hydrolase fold DLH PF01738.18 CBZ26323.1 - 0.04 13.5 0.1 0.09 12.3 0.1 1.5 1 0 0 1 1 1 0 Dienelactone hydrolase family Macro_2 PF14519.6 CBZ26323.1 - 0.16 11.3 0.0 0.24 10.7 0.0 1.2 1 0 0 1 1 1 0 Macro-like domain Peptidase_S15 PF02129.18 CBZ26323.1 - 0.28 10.7 3.0 1.6 8.2 0.1 2.6 2 1 1 3 3 3 0 X-Pro dipeptidyl-peptidase (S15 family) RL10P_insert PF17777.1 CBZ26324.1 - 9.8e-25 86.4 0.0 1.7e-24 85.6 0.0 1.4 1 0 0 1 1 1 1 Insertion domain in 60S ribosomal protein L10P Ribosomal_L10 PF00466.20 CBZ26324.1 - 5.6e-20 71.4 0.1 8.8e-20 70.7 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L10 DUF3577 PF12101.8 CBZ26324.1 - 0.026 14.3 0.2 0.041 13.7 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3577) VPS9 PF02204.18 CBZ26325.1 - 1.2e-30 105.8 0.0 5.6e-30 103.6 0.0 2.1 2 0 0 2 2 2 1 Vacuolar sorting protein 9 (VPS9) domain Prok-TraM PF09228.10 CBZ26325.1 - 0.055 13.8 0.5 12 6.3 0.1 3.3 3 0 0 3 3 3 0 Prokaryotic Transcriptional repressor TraM SKA2 PF16740.5 CBZ26326.1 - 0.0024 17.6 3.6 0.0039 16.9 3.6 1.3 1 0 0 1 1 1 1 Spindle and kinetochore-associated protein 2 TMF_DNA_bd PF12329.8 CBZ26326.1 - 0.021 14.8 8.6 0.46 10.5 0.2 2.4 2 1 0 2 2 2 0 TATA element modulatory factor 1 DNA binding FlxA PF14282.6 CBZ26326.1 - 0.035 14.1 1.8 0.05 13.6 1.1 1.7 1 1 1 2 2 2 0 FlxA-like protein HALZ PF02183.18 CBZ26326.1 - 0.049 13.8 0.0 0.049 13.8 0.0 2.7 3 1 0 3 3 2 0 Homeobox associated leucine zipper Golgin_A5 PF09787.9 CBZ26326.1 - 0.077 12.4 7.5 0.18 11.3 7.5 1.5 1 1 0 1 1 1 0 Golgin subfamily A member 5 Atg14 PF10186.9 CBZ26326.1 - 0.078 12.0 7.0 0.11 11.5 7.0 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 AAA_13 PF13166.6 CBZ26326.1 - 0.096 11.3 2.0 0.13 10.9 2.0 1.1 1 0 0 1 1 1 0 AAA domain ZapB PF06005.12 CBZ26326.1 - 0.11 13.0 11.6 3.9 8.0 11.2 2.3 1 1 0 1 1 1 0 Cell division protein ZapB Fib_alpha PF08702.10 CBZ26326.1 - 0.11 12.7 1.5 0.14 12.3 1.5 1.2 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family GIT_CC PF16559.5 CBZ26326.1 - 0.13 12.1 4.5 0.3 11.0 0.2 2.5 3 0 0 3 3 3 0 GIT coiled-coil Rho guanine nucleotide exchange factor GAS PF13851.6 CBZ26326.1 - 0.13 11.6 8.1 0.18 11.2 8.1 1.1 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding Cnn_1N PF07989.11 CBZ26326.1 - 0.14 12.3 6.7 3.7 7.8 1.9 2.2 2 0 0 2 2 2 0 Centrosomin N-terminal motif 1 OmpH PF03938.14 CBZ26326.1 - 0.16 12.3 3.6 0.2 12.0 3.6 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) FUSC PF04632.12 CBZ26326.1 - 0.17 10.3 2.9 0.19 10.2 2.9 1.0 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF3450 PF11932.8 CBZ26326.1 - 0.23 10.7 6.8 0.13 11.5 0.5 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) Syntaxin-6_N PF09177.11 CBZ26326.1 - 0.33 11.5 4.5 2.1 9.0 0.4 2.1 1 1 1 2 2 2 0 Syntaxin 6, N-terminal YabA PF06156.13 CBZ26326.1 - 0.34 11.6 7.3 1.2 9.8 1.6 2.2 1 1 1 2 2 2 0 Initiation control protein YabA FapA PF03961.13 CBZ26326.1 - 0.43 9.1 2.5 0.62 8.6 2.5 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A UPF0242 PF06785.11 CBZ26326.1 - 0.48 10.5 4.4 0.64 10.1 4.4 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Csm1_N PF18504.1 CBZ26326.1 - 0.49 10.8 5.9 1.4 9.3 0.3 2.6 2 1 1 3 3 3 0 Csm1 N-terminal domain TSC22 PF01166.18 CBZ26326.1 - 0.66 10.3 6.6 2.2 8.6 0.5 2.8 2 1 1 3 3 3 0 TSC-22/dip/bun family TetR_C_24 PF17932.1 CBZ26326.1 - 0.96 9.7 5.5 2.6 8.4 0.8 2.1 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain bZIP_2 PF07716.15 CBZ26326.1 - 1.1 9.4 11.7 2.8 8.1 0.6 3.1 2 1 1 3 3 3 0 Basic region leucine zipper Spc7 PF08317.11 CBZ26326.1 - 1.2 8.0 8.1 1.6 7.6 8.1 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein kleA_kleC PF17383.2 CBZ26326.1 - 1.4 9.3 10.1 2.2 8.6 1.5 2.3 1 1 1 2 2 2 0 Uncharacterized KorC regulated protein A CCDC-167 PF15188.6 CBZ26326.1 - 1.6 9.1 10.7 4.7 7.6 1.1 2.3 1 1 1 2 2 2 0 Coiled-coil domain-containing protein 167 RIC3 PF15361.6 CBZ26326.1 - 3.3 8.1 6.2 2.3 8.6 0.5 2.1 2 0 0 2 2 2 0 Resistance to inhibitors of cholinesterase homologue 3 XhlA PF10779.9 CBZ26326.1 - 7.5 6.8 7.2 2.4 8.4 0.6 2.3 2 1 0 2 2 2 0 Haemolysin XhlA DUF4140 PF13600.6 CBZ26326.1 - 8.1 7.0 8.8 9 6.8 2.7 2.4 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) Macoilin PF09726.9 CBZ26326.1 - 8.7 4.8 8.8 10 4.5 8.8 1.0 1 0 0 1 1 1 0 Macoilin family Cyt-b5 PF00173.28 CBZ26327.1 - 1.5e-15 57.1 0.0 1.7e-15 56.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Abhydrolase_1 PF00561.20 CBZ26329.1 - 0.0051 16.5 0.0 4.1 7.0 0.0 2.9 3 0 0 3 3 3 2 alpha/beta hydrolase fold End_tail_spike PF12219.8 CBZ26329.1 - 0.087 12.9 0.2 0.28 11.2 0.2 1.8 1 0 0 1 1 1 0 Catalytic domain of bacteriophage endosialidase Abhydrolase_6 PF12697.7 CBZ26329.1 - 0.56 10.8 24.9 3.8 8.0 7.1 4.6 3 2 0 4 4 4 0 Alpha/beta hydrolase family WD40 PF00400.32 CBZ26330.1 - 1.3e-10 41.6 6.3 0.063 14.2 0.0 5.9 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBZ26330.1 - 1.3e-07 31.8 0.0 0.39 11.0 0.0 4.6 4 1 0 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Flavodoxin_1 PF00258.25 CBZ26331.1 - 6.9e-29 100.9 0.0 7.9e-23 81.2 0.0 4.7 5 1 0 5 5 5 3 Flavodoxin FAD_binding_1 PF00667.20 CBZ26331.1 - 3.8e-17 62.6 0.0 7.3e-17 61.7 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain NAD_binding_1 PF00175.21 CBZ26331.1 - 2.5e-10 41.0 0.0 8.9e-10 39.2 0.0 2.0 1 1 0 1 1 1 1 Oxidoreductase NAD-binding domain RabGAP-TBC PF00566.18 CBZ26332.1 - 0.0035 17.0 0.2 0.01 15.5 0.2 1.9 1 1 0 1 1 1 1 Rab-GTPase-TBC domain PIG-P PF08510.12 CBZ26334.1 - 1e-27 96.5 1.6 1.2e-27 96.3 1.6 1.0 1 0 0 1 1 1 1 PIG-P DPM2 PF07297.12 CBZ26334.1 - 0.058 13.7 8.7 0.17 12.2 8.7 1.8 1 1 0 1 1 1 0 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) LOB PF03195.14 CBZ26335.1 - 9.4 6.9 7.6 24 5.6 0.0 3.8 4 0 0 4 4 4 0 Lateral organ boundaries (LOB) domain FAST_1 PF06743.15 CBZ26336.1 - 0.00038 20.4 0.2 5.2 7.1 0.1 5.1 5 1 1 6 6 6 4 FAST kinase-like protein, subdomain 1 DUF1749 PF08538.10 CBZ26337.1 - 5.4e-14 52.0 0.0 7.5e-14 51.5 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1749) Hydrolase_4 PF12146.8 CBZ26337.1 - 0.05 12.9 0.2 0.095 11.9 0.2 1.5 1 1 0 1 1 1 0 Serine aminopeptidase, S33 CAMSAP_CC1 PF17095.5 CBZ26338.1 - 8.3 6.3 13.1 0.12 12.3 0.4 3.7 3 0 0 3 3 3 0 Spectrin-binding region of Ca2+-Calmodulin Methyltransf_24 PF13578.6 CBZ26339.1 - 0.0016 19.4 1.0 0.015 16.3 0.3 2.5 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_30 PF05430.11 CBZ26339.1 - 0.013 15.4 0.0 0.026 14.4 0.0 1.5 1 0 0 1 1 1 0 S-adenosyl-L-methionine-dependent methyltransferase PPR_2 PF13041.6 CBZ26340.1 - 1.1e-39 134.4 3.3 7e-16 58.2 0.6 5.1 3 1 2 5 5 5 5 PPR repeat family PPR_3 PF13812.6 CBZ26340.1 - 3e-35 120.1 0.1 6.6e-14 51.7 0.2 5.1 2 1 3 5 5 5 4 Pentatricopeptide repeat domain PPR PF01535.20 CBZ26340.1 - 3e-34 114.9 1.0 4.5e-06 26.5 0.0 6.2 6 0 0 6 6 6 5 PPR repeat PPR_1 PF12854.7 CBZ26340.1 - 9.4e-28 95.6 0.1 1.9e-08 33.8 0.0 6.2 6 0 0 6 6 6 5 PPR repeat PPR_long PF17177.4 CBZ26340.1 - 2.9e-21 75.8 0.1 1.2e-15 57.5 0.1 2.3 1 1 1 2 2 2 2 Pentacotripeptide-repeat region of PRORP TPR_14 PF13428.6 CBZ26340.1 - 2.9e-06 27.6 1.2 6.9 7.8 0.1 5.3 5 1 2 7 7 7 2 Tetratricopeptide repeat ATP13 PF12921.7 CBZ26340.1 - 0.023 14.6 0.0 37 4.2 0.0 3.5 2 1 0 3 3 3 0 Mitochondrial ATPase expression WD40 PF00400.32 CBZ26341.1 - 2.8e-36 122.9 15.4 3.3e-06 27.7 0.1 8.3 8 0 0 8 8 8 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBZ26341.1 - 3.5e-07 30.4 0.1 0.19 12.0 0.0 5.2 2 2 3 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 CBZ26341.1 - 0.0042 16.4 0.0 0.073 12.4 0.0 2.2 1 1 1 2 2 2 1 WD40-like domain Roc PF08477.13 CBZ26342.1 - 7.1e-05 23.0 0.0 0.0025 18.0 0.0 2.4 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase AAA_16 PF13191.6 CBZ26342.1 - 0.015 15.7 0.1 0.04 14.3 0.1 1.7 1 0 0 1 1 1 0 AAA ATPase domain SRPRB PF09439.10 CBZ26342.1 - 0.016 14.6 0.1 0.2 11.1 0.0 2.1 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 CBZ26342.1 - 0.042 13.9 0.0 0.093 12.8 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_7 PF12775.7 CBZ26342.1 - 0.047 13.2 0.0 0.084 12.4 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region Ras PF00071.22 CBZ26342.1 - 0.053 13.1 0.0 0.41 10.2 0.0 2.2 2 0 0 2 2 2 0 Ras family FBD PF08387.10 CBZ26342.1 - 0.18 11.7 0.0 0.38 10.7 0.0 1.5 1 0 0 1 1 1 0 FBD LRR_4 PF12799.7 CBZ26343.1 - 5.2e-27 93.5 38.4 0.00014 22.2 0.5 13.9 10 4 5 16 16 16 9 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CBZ26343.1 - 1.2e-14 53.8 35.1 6.4e-05 22.6 4.0 7.9 6 3 1 7 7 7 4 Leucine rich repeat LRR_6 PF13516.6 CBZ26343.1 - 2.1e-05 24.2 43.4 0.0067 16.4 0.3 12.8 15 0 0 15 15 15 3 Leucine Rich repeat LRR_1 PF00560.33 CBZ26343.1 - 1.2 9.9 30.9 46 5.1 0.1 11.5 12 0 0 12 12 12 0 Leucine Rich Repeat CITED PF04487.12 CBZ26344.1 - 0.085 12.9 0.2 0.17 12.0 0.2 1.5 1 0 0 1 1 1 0 CITED Spc29 PF17082.5 CBZ26344.1 - 0.12 12.2 0.0 0.27 11.0 0.0 1.6 1 0 0 1 1 1 0 Spindle Pole Component 29 2_5_RNA_ligase2 PF13563.6 CBZ26345.1 - 0.0011 18.8 0.0 0.0033 17.3 0.0 1.8 1 1 1 2 2 2 1 2'-5' RNA ligase superfamily MtN3_slv PF03083.16 CBZ26346.1 - 5.6e-24 84.0 20.6 5.6e-14 51.9 1.1 2.7 3 0 0 3 3 3 2 Sugar efflux transporter for intercellular exchange LRR_9 PF14580.6 CBZ26347.1 - 3.5e-13 49.4 0.0 2.7e-09 36.8 0.2 2.3 1 1 0 2 2 2 2 Leucine-rich repeat LRR_4 PF12799.7 CBZ26347.1 - 7.9e-12 45.2 11.4 0.00034 20.9 0.1 4.4 3 1 2 5 5 5 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CBZ26347.1 - 4.2e-11 42.4 9.6 2.1e-07 30.6 0.7 3.6 3 2 0 3 3 3 2 Leucine rich repeat LRR_6 PF13516.6 CBZ26347.1 - 0.18 11.9 0.2 0.18 11.9 0.2 4.2 5 0 0 5 5 5 0 Leucine Rich repeat LRR_1 PF00560.33 CBZ26347.1 - 0.79 10.5 8.3 42 5.2 0.4 5.2 4 1 0 4 4 4 0 Leucine Rich Repeat RNase_PH PF01138.21 CBZ26348.1 - 5.3e-14 52.8 0.2 9.9e-14 52.0 0.2 1.5 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 LRRNT PF01462.18 CBZ26348.1 - 3.6 7.4 0.0 3.6 7.4 0.0 3.3 4 0 0 4 4 4 0 Leucine rich repeat N-terminal domain Clathrin PF00637.20 CBZ26349.1 - 4e-07 30.0 0.4 4e-07 30.0 0.4 2.7 4 0 0 4 4 4 1 Region in Clathrin and VPS zf-C3HC4_2 PF13923.6 CBZ26349.1 - 0.0016 18.2 0.7 0.0042 16.9 0.7 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Vps8 PF12816.7 CBZ26349.1 - 0.0038 16.8 0.1 16 4.9 0.0 4.0 5 0 0 5 5 5 2 Golgi CORVET complex core vacuolar protein 8 zf-RING_2 PF13639.6 CBZ26349.1 - 0.015 15.7 0.6 0.015 15.7 0.6 2.2 2 0 0 2 2 2 0 Ring finger domain SCAB-PH PF17684.1 CBZ26349.1 - 0.16 12.2 0.1 0.37 11.1 0.1 1.5 1 0 0 1 1 1 0 PH domain of plant-specific actin-binding protein zf-RING_5 PF14634.6 CBZ26349.1 - 0.17 11.9 1.4 0.51 10.4 1.4 1.8 1 0 0 1 1 1 0 zinc-RING finger domain zf-rbx1 PF12678.7 CBZ26349.1 - 0.72 10.2 7.8 0.13 12.5 3.2 2.3 2 0 0 2 2 2 0 RING-H2 zinc finger domain Nucleoplasmin PF03066.15 CBZ26350.1 - 0.057 13.9 2.5 0.2 12.2 2.5 2.1 1 0 0 1 1 1 0 Nucleoplasmin/nucleophosmin domain Med5 PF08689.10 CBZ26350.1 - 6.4 4.4 15.2 8.6 4.0 15.2 1.1 1 0 0 1 1 1 0 Mediator complex subunit Med5 CH PF00307.31 CBZ26351.1 - 1.4e-11 44.5 0.0 3.1e-11 43.4 0.0 1.5 1 0 0 1 1 1 1 Calponin homology (CH) domain IF-2B PF01008.17 CBZ26352.1 - 3e-70 236.6 0.6 3.7e-70 236.3 0.6 1.1 1 0 0 1 1 1 1 Initiation factor 2 subunit family UPF0029 PF01205.19 CBZ26353.1 - 6.1e-30 103.7 0.0 1.2e-29 102.7 0.0 1.5 1 0 0 1 1 1 1 Uncharacterized protein family UPF0029 RWD PF05773.22 CBZ26353.1 - 0.00082 19.6 0.3 0.0085 16.4 0.3 2.2 1 1 0 1 1 1 1 RWD domain 2OG-FeII_Oxy_2 PF13532.6 CBZ26354.1 - 9e-07 29.3 0.0 5.2e-06 26.8 0.0 2.2 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily LPP PF04728.13 CBZ26354.1 - 1.6 9.1 3.2 1.3 9.5 0.9 1.9 2 0 0 2 2 2 0 Lipoprotein leucine-zipper START PF01852.19 CBZ26355.1 - 1.5e-05 24.5 0.0 0.094 12.1 0.0 2.5 2 0 0 2 2 2 2 START domain PepSY_2 PF13670.6 CBZ26355.1 - 5.1 7.2 8.6 1.5 8.9 5.1 1.9 2 0 0 2 2 2 0 Peptidase propeptide and YPEB domain DnaJ PF00226.31 CBZ26356.1 - 2.3e-05 24.4 0.0 9.6e-05 22.4 0.0 2.0 2 0 0 2 2 2 1 DnaJ domain HTH_38 PF13936.6 CBZ26356.1 - 0.0034 17.1 0.0 0.0085 15.8 0.0 1.7 1 0 0 1 1 1 1 Helix-turn-helix domain LPD22 PF18834.1 CBZ26356.1 - 0.31 11.3 2.0 7.5 6.8 0.1 2.7 2 1 1 3 3 3 0 Large polyvalent protein associated domain 22 Tubulin PF00091.25 CBZ26358.1 - 1.2e-32 113.7 0.0 7.2e-24 85.1 0.0 2.4 1 1 1 2 2 2 2 Tubulin/FtsZ family, GTPase domain Tubulin_2 PF13809.6 CBZ26358.1 - 0.00067 18.9 0.1 0.0012 18.1 0.1 1.4 1 0 0 1 1 1 1 Tubulin like Ribosomal_S2 PF00318.20 CBZ26360.1 - 1.1e-28 100.0 0.6 1.4e-16 60.4 0.2 2.1 1 1 1 2 2 2 2 Ribosomal protein S2 40S_SA_C PF16122.5 CBZ26360.1 - 0.0037 18.6 1.9 0.0071 17.7 1.9 1.5 1 0 0 1 1 1 1 40S ribosomal protein SA C-terminus Sulfotransfer_1 PF00685.27 CBZ26360.1 - 0.021 14.3 0.0 0.028 13.9 0.0 1.2 1 0 0 1 1 1 0 Sulfotransferase domain Fcf1 PF04900.12 CBZ26362.1 - 0.058 13.8 0.1 0.18 12.2 0.1 1.8 1 0 0 1 1 1 0 Fcf1 MAP65_ASE1 PF03999.12 CBZ26362.1 - 0.33 9.6 10.2 0.091 11.5 4.7 2.3 1 1 2 3 3 3 0 Microtubule associated protein (MAP65/ASE1 family) GIT_CC PF16559.5 CBZ26362.1 - 0.75 9.7 10.5 1.2 9.1 0.1 4.5 5 0 0 5 5 5 0 GIT coiled-coil Rho guanine nucleotide exchange factor DUF948 PF06103.11 CBZ26362.1 - 3.3 8.0 6.5 30 5.0 0.7 3.7 3 1 1 4 4 4 0 Bacterial protein of unknown function (DUF948) DUF16 PF01519.16 CBZ26362.1 - 3.9 8.0 13.6 1.4 9.5 1.6 3.4 1 1 2 3 3 3 0 Protein of unknown function DUF16 DUF2894 PF11445.8 CBZ26362.1 - 4.8 7.6 11.9 1.5 9.2 8.4 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF2894) zf-C4H2 PF10146.9 CBZ26362.1 - 5.1 7.4 17.2 0.5 10.6 1.8 2.7 1 1 1 2 2 2 0 Zinc finger-containing protein Baculo_PEP_C PF04513.12 CBZ26362.1 - 7.1 6.7 8.2 35 4.4 3.4 3.5 2 1 2 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus SKA2 PF16740.5 CBZ26362.1 - 9.6 6.0 20.4 2.2 8.1 1.8 3.9 3 1 0 3 3 3 0 Spindle and kinetochore-associated protein 2 Hexapep PF00132.24 CBZ26363.1 - 4.8e-09 35.6 11.2 0.035 13.8 0.2 5.0 3 1 1 4 4 4 4 Bacterial transferase hexapeptide (six repeats) NOB1_Zn_bind PF08772.11 CBZ26365.1 - 7.1e-26 90.2 0.2 1.4e-25 89.2 0.2 1.5 1 0 0 1 1 1 1 Nin one binding (NOB1) Zn-ribbon like PIN_6 PF17146.4 CBZ26365.1 - 2.3e-22 79.3 0.1 4.8e-22 78.3 0.1 1.6 1 0 0 1 1 1 1 PIN domain of ribonuclease DUF35_N PF12172.8 CBZ26365.1 - 0.0025 17.7 1.0 0.0056 16.5 1.0 1.6 1 0 0 1 1 1 1 Rubredoxin-like zinc ribbon domain (DUF35_N) DZR PF12773.7 CBZ26365.1 - 0.065 13.3 0.3 0.12 12.4 0.3 1.4 1 0 0 1 1 1 0 Double zinc ribbon zf-NADH-PPase PF09297.11 CBZ26365.1 - 8.6 6.1 7.0 23 4.7 1.5 2.9 3 0 0 3 3 3 0 NADH pyrophosphatase zinc ribbon domain CK_II_beta PF01214.18 CBZ26368.1 - 2.2e-73 246.0 0.0 2.7e-73 245.7 0.0 1.1 1 0 0 1 1 1 1 Casein kinase II regulatory subunit HU-CCDC81_euk_2 PF18289.1 CBZ26370.1 - 1.4e-16 60.4 0.0 2.8e-16 59.4 0.0 1.5 1 0 0 1 1 1 1 CCDC81 eukaryotic HU domain 2 HU-CCDC81_euk_1 PF14908.6 CBZ26370.1 - 6.6e-14 51.8 0.0 1e-13 51.2 0.0 1.3 1 0 0 1 1 1 1 CCDC81 eukaryotic HU domain 1 Ribosomal_S2 PF00318.20 CBZ26371.1 - 1.1e-28 100.0 0.6 1.4e-16 60.4 0.2 2.1 1 1 1 2 2 2 2 Ribosomal protein S2 40S_SA_C PF16122.5 CBZ26371.1 - 0.0061 17.9 2.4 0.012 17.0 2.4 1.5 1 0 0 1 1 1 1 40S ribosomal protein SA C-terminus Sulfotransfer_1 PF00685.27 CBZ26371.1 - 0.021 14.3 0.0 0.028 13.9 0.0 1.2 1 0 0 1 1 1 0 Sulfotransferase domain Porin_3 PF01459.22 CBZ26372.1 - 0.0025 17.3 0.4 0.011 15.2 0.3 2.0 2 1 0 2 2 2 1 Eukaryotic porin DUF1869 PF08956.10 CBZ26372.1 - 0.079 12.9 0.1 0.87 9.5 0.0 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF1869) VHS PF00790.19 CBZ26373.1 - 2.8e-12 46.7 0.2 1.3e-10 41.3 0.0 2.2 2 0 0 2 2 2 2 VHS domain Kinesin PF00225.23 CBZ26374.1 - 8e-24 84.2 9.4 3.1e-17 62.5 0.0 3.6 4 0 0 4 4 4 2 Kinesin motor domain Microtub_bd PF16796.5 CBZ26374.1 - 5.7e-08 32.8 0.9 5.1e-07 29.7 0.0 3.0 2 1 0 2 2 2 1 Microtubule binding Ribosomal_L13 PF00572.18 CBZ26374.1 - 1.1 9.5 7.0 0.52 10.6 2.6 2.2 1 1 1 2 2 2 0 Ribosomal protein L13 MA3 PF02847.17 CBZ26375.1 - 6.9e-13 48.6 1.2 6.9e-13 48.6 1.2 1.7 2 0 0 2 2 2 1 MA3 domain MIF4G PF02854.19 CBZ26375.1 - 5.1e-05 23.0 1.4 0.00019 21.2 0.1 2.3 2 1 0 2 2 2 1 MIF4G domain VPS28 PF03997.12 CBZ26376.1 - 2.7e-44 151.1 0.1 3e-44 151.0 0.1 1.0 1 0 0 1 1 1 1 VPS28 protein Aldedh PF00171.22 CBZ26377.1 - 2.8e-129 431.6 0.7 3.2e-129 431.4 0.7 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family SNF2_N PF00176.23 CBZ26378.1 - 8e-61 205.7 0.0 1.5e-60 204.8 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 CBZ26378.1 - 6e-18 65.2 0.0 1.5e-17 63.9 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 CBZ26378.1 - 3.3e-08 33.7 0.0 6.6e-08 32.7 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 CBZ26378.1 - 0.00034 20.4 0.0 0.00065 19.5 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase ERCC3_RAD25_C PF16203.5 CBZ26378.1 - 0.012 14.8 0.1 0.051 12.8 0.0 1.9 2 0 0 2 2 2 0 ERCC3/RAD25/XPB C-terminal helicase Sec8_exocyst PF04048.14 CBZ26378.1 - 0.1 12.5 0.0 0.26 11.2 0.0 1.6 1 0 0 1 1 1 0 Sec8 exocyst complex component specific domain PQQ_3 PF13570.6 CBZ26380.1 - 4.4 7.9 7.1 1.2 9.7 0.1 4.0 4 0 0 4 4 4 0 PQQ-like domain PRKCSH PF07915.13 CBZ26381.1 - 0.04 14.9 0.8 0.097 13.7 0.8 1.7 1 1 0 1 1 1 0 Glucosidase II beta subunit-like protein Glyco_hydro_65m PF03632.15 CBZ26383.1 - 1.6e-70 237.9 0.0 3.4e-70 236.9 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 65 central catalytic domain Glyco_hydro_65N PF03636.15 CBZ26383.1 - 5e-26 91.7 0.1 9.8e-26 90.8 0.1 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 65, N-terminal domain Glyco_hydro_65C PF03633.15 CBZ26383.1 - 1.5e-05 24.8 0.0 3.8e-05 23.5 0.0 1.7 1 0 0 1 1 1 1 Glycosyl hydrolase family 65, C-terminal domain HAD_2 PF13419.6 CBZ26383.1 - 0.011 15.8 0.0 0.022 14.9 0.0 1.4 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase Adaptin_N PF01602.20 CBZ26385.1 - 7.4e-78 262.4 0.0 9.4e-78 262.0 0.0 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 CBZ26385.1 - 1.7e-13 50.9 0.6 4.6e-13 49.5 0.6 1.7 1 0 0 1 1 1 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 CBZ26385.1 - 5.5e-06 26.7 8.4 0.00024 21.4 2.2 4.2 2 2 1 4 4 4 2 HEAT repeats HEAT PF02985.22 CBZ26385.1 - 0.0013 18.8 8.4 0.64 10.4 0.2 4.4 4 0 0 4 4 4 3 HEAT repeat Exo_endo_phos PF03372.23 CBZ26386.1 - 2.7e-09 36.9 0.0 5.7e-06 26.0 0.0 2.6 2 1 0 2 2 2 2 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.6 CBZ26386.1 - 0.039 13.8 0.0 0.14 12.0 0.0 1.9 2 0 0 2 2 2 0 Endonuclease-reverse transcriptase HEAT_2 PF13646.6 CBZ26387.1 - 0.021 15.2 11.9 1.9 8.9 0.9 5.6 4 1 0 4 4 4 0 HEAT repeats HEAT_EZ PF13513.6 CBZ26387.1 - 0.41 11.2 12.4 0.88 10.2 0.7 5.9 4 2 1 5 5 5 0 HEAT-like repeat HEAT PF02985.22 CBZ26387.1 - 2.8 8.4 16.3 1.4 9.4 0.0 6.3 7 1 1 8 8 8 0 HEAT repeat TSKS PF15358.6 CBZ26388.1 - 0.022 13.2 2.1 0.64 8.3 0.6 2.1 1 1 1 2 2 2 0 Testis-specific serine kinase substrate HTH_22 PF13309.6 CBZ26388.1 - 0.053 13.6 2.5 5.5 7.1 0.0 3.6 3 1 0 3 3 3 0 HTH domain DUF737 PF05300.11 CBZ26388.1 - 0.059 13.7 9.6 0.092 13.1 9.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF737) SIX1_SD PF16878.5 CBZ26388.1 - 0.36 11.4 5.0 0.57 10.7 5.0 1.5 1 1 0 1 1 1 0 Transcriptional regulator, SIX1, N-terminal SD domain GST_C_2 PF13410.6 CBZ26391.1 - 1.9e-06 27.8 0.5 6.5e-06 26.1 0.0 2.2 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 CBZ26391.1 - 0.001 19.2 0.0 0.0023 18.1 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 CBZ26391.1 - 0.13 12.5 0.0 0.38 11.0 0.0 1.8 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Pkinase PF00069.25 CBZ26394.1 - 1.5e-58 198.2 0.0 2.3e-58 197.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ26394.1 - 5.1e-36 124.3 0.0 7.7e-36 123.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CBZ26394.1 - 2e-10 40.5 0.0 2.4e-08 33.7 0.0 2.2 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 CBZ26394.1 - 0.00027 21.0 0.0 0.12 12.3 0.0 3.6 2 1 1 3 3 3 1 Phosphotransferase enzyme family C1_2 PF03107.16 CBZ26394.1 - 0.004 17.4 3.8 0.004 17.4 3.8 2.1 2 0 0 2 2 2 1 C1 domain Kdo PF06293.14 CBZ26394.1 - 0.015 14.7 0.0 0.031 13.6 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.11 CBZ26394.1 - 0.022 13.8 0.0 0.041 13.0 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 FYVE_2 PF02318.16 CBZ26394.1 - 0.052 13.8 5.2 0.16 12.2 5.2 1.8 1 0 0 1 1 1 0 FYVE-type zinc finger Haspin_kinase PF12330.8 CBZ26394.1 - 0.093 11.7 0.0 0.15 11.0 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain zf-piccolo PF05715.13 CBZ26394.1 - 0.56 10.4 9.9 0.069 13.3 5.5 1.9 2 0 0 2 2 2 0 Piccolo Zn-finger SF1-HH PF16275.5 CBZ26394.1 - 0.97 9.8 4.0 0.64 10.4 0.2 2.6 2 1 1 3 3 3 0 Splicing factor 1 helix-hairpin domain zf-UDP PF14569.6 CBZ26394.1 - 2.3 8.4 10.2 2.3 8.4 6.3 2.7 3 0 0 3 3 3 0 Zinc-binding RING-finger Ubie_methyltran PF01209.18 CBZ26395.1 - 2.2e-110 367.5 0.0 2.6e-110 367.3 0.0 1.0 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.6 CBZ26395.1 - 4.8e-16 59.2 0.0 2.5e-15 56.9 0.0 2.2 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 CBZ26395.1 - 4.4e-15 56.1 0.0 1.3e-14 54.6 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CBZ26395.1 - 2e-09 37.4 0.0 3e-09 36.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CBZ26395.1 - 7.7e-07 29.8 0.0 1.2e-06 29.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 CBZ26395.1 - 0.00013 21.9 0.0 0.00018 21.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.15 CBZ26395.1 - 0.00013 21.9 0.0 0.13 12.1 0.0 2.4 2 1 0 2 2 2 2 Hypothetical methyltransferase Hydrophob_seed PF14547.6 CBZ26396.1 - 0.064 13.5 0.3 0.15 12.3 0.3 1.6 1 0 0 1 1 1 0 Hydrophobic seed protein WD40 PF00400.32 CBZ26396.1 - 0.27 12.2 3.7 6.3 7.9 0.0 3.6 3 1 0 3 3 3 0 WD domain, G-beta repeat HEV_ORF1 PF02444.16 CBZ26396.1 - 0.43 11.1 6.9 0.12 12.9 3.2 2.0 2 0 0 2 2 2 0 Hepatitis E virus ORF-2 (Putative capsid protein) Y_phosphatase PF00102.27 CBZ26397.1 - 5.1e-67 225.9 0.0 6.6e-67 225.5 0.0 1.1 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.6 CBZ26397.1 - 0.00038 20.5 0.0 0.0007 19.6 0.0 1.4 1 0 0 1 1 1 1 Tyrosine phosphatase family DSPc PF00782.20 CBZ26397.1 - 0.00062 19.6 0.0 0.0011 18.8 0.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.6 CBZ26397.1 - 0.046 13.8 0.0 0.12 12.5 0.0 1.6 1 0 0 1 1 1 0 Inositol hexakisphosphate Pyr_redox_2 PF07992.14 CBZ26398.1 - 1.7e-51 175.2 0.0 2.2e-51 174.9 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 CBZ26398.1 - 1.2e-10 41.8 0.0 1.8e-07 31.6 0.1 2.8 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 CBZ26398.1 - 7.8e-05 21.9 0.0 0.061 12.4 0.0 2.7 3 0 0 3 3 3 2 FAD binding domain NAD_binding_8 PF13450.6 CBZ26398.1 - 0.00015 21.9 0.0 0.8 10.0 0.0 2.5 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain DAO PF01266.24 CBZ26398.1 - 0.0082 15.8 0.2 1 8.9 0.0 2.9 2 1 1 3 3 3 1 FAD dependent oxidoreductase GIDA PF01134.22 CBZ26398.1 - 0.0082 15.3 0.2 1.3 8.1 0.0 2.8 3 0 0 3 3 3 1 Glucose inhibited division protein A Pyr_redox_3 PF13738.6 CBZ26398.1 - 0.039 13.2 0.0 2.4 7.3 0.0 2.7 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 CBZ26398.1 - 0.077 12.0 0.1 9 5.2 0.0 2.8 3 0 0 3 3 3 0 Lycopene cyclase protein Pribosyltran_N PF13793.6 CBZ26399.1 - 5.3e-40 136.0 0.0 1.4e-39 134.6 0.0 1.7 1 0 0 1 1 1 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.6 CBZ26399.1 - 2.8e-29 102.5 3.6 7.1e-29 101.1 1.3 2.2 1 1 1 2 2 2 1 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.27 CBZ26399.1 - 1.4e-15 57.2 0.2 3.3e-15 55.9 0.2 1.6 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.6 CBZ26399.1 - 0.00017 21.1 0.3 0.0004 19.9 0.1 1.7 2 0 0 2 2 2 1 Uracil phosphoribosyltransferase IL2 PF00715.17 CBZ26399.1 - 0.1 12.6 0.1 0.21 11.5 0.1 1.5 1 0 0 1 1 1 0 Interleukin 2 BCS1_N PF08740.11 CBZ26400.1 - 4.5e-30 105.0 1.8 7.4e-30 104.3 1.8 1.3 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.29 CBZ26400.1 - 5e-11 43.2 0.3 5.9e-05 23.5 0.3 3.2 2 1 1 3 3 3 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 CBZ26400.1 - 0.0014 18.4 0.0 0.0028 17.4 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 CBZ26400.1 - 0.0014 19.0 0.1 0.014 15.8 0.1 2.5 1 1 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.14 CBZ26400.1 - 0.0015 18.5 0.1 0.006 16.6 0.0 2.0 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_33 PF13671.6 CBZ26400.1 - 0.0037 17.4 0.1 0.012 15.8 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.6 CBZ26400.1 - 0.0068 16.2 0.1 0.03 14.1 0.0 1.9 1 1 1 2 2 2 1 AAA domain TIP49 PF06068.13 CBZ26400.1 - 0.029 13.6 0.0 0.054 12.7 0.0 1.3 1 0 0 1 1 1 0 TIP49 P-loop domain ATPase PF06745.13 CBZ26400.1 - 0.084 12.2 0.0 0.16 11.3 0.0 1.4 1 0 0 1 1 1 0 KaiC AAA_6 PF12774.7 CBZ26400.1 - 0.16 10.9 0.0 0.26 10.2 0.0 1.2 1 0 0 1 1 1 0 Hydrolytic ATP binding site of dynein motor region AAA_3 PF07726.11 CBZ26400.1 - 0.17 11.8 0.0 0.31 10.9 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AIRS_C PF02769.22 CBZ26401.1 - 3.9e-17 62.8 0.0 7.7e-17 61.9 0.0 1.5 1 0 0 1 1 1 1 AIR synthase related protein, C-terminal domain AIRS PF00586.24 CBZ26401.1 - 5.9e-09 36.5 0.1 2e-08 34.8 0.1 1.9 1 0 0 1 1 1 1 AIR synthase related protein, N-terminal domain Extensin-like_C PF06904.12 CBZ26401.1 - 0.12 12.3 0.0 0.28 11.2 0.0 1.5 2 0 0 2 2 2 0 Extensin-like protein C-terminus SF1-HH PF16275.5 CBZ26402.1 - 4e-07 30.4 0.1 8.2e-07 29.4 0.1 1.6 1 0 0 1 1 1 1 Splicing factor 1 helix-hairpin domain KH_1 PF00013.29 CBZ26402.1 - 5e-06 26.3 0.0 1.1e-05 25.2 0.0 1.4 1 0 0 1 1 1 1 KH domain DUF3824 PF12868.7 CBZ26402.1 - 0.28 11.9 8.1 0.61 10.7 8.1 1.5 1 0 0 1 1 1 0 Domain of unknwon function (DUF3824) TylF PF05711.11 CBZ26403.1 - 3.1e-20 72.5 0.0 1.4e-19 70.4 0.0 2.0 1 1 0 1 1 1 1 Macrocin-O-methyltransferase (TylF) Methyltransf_24 PF13578.6 CBZ26403.1 - 3.3e-07 31.3 0.1 4.9e-06 27.5 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain CmcI PF04989.12 CBZ26403.1 - 0.047 13.4 0.0 0.11 12.1 0.0 1.6 1 0 0 1 1 1 0 Cephalosporin hydroxylase SEP PF08059.13 CBZ26404.1 - 1.8e-08 34.8 0.0 4.9e-08 33.4 0.0 1.8 1 0 0 1 1 1 1 SEP domain FPP PF05911.11 CBZ26404.1 - 0.0003 19.2 4.8 0.00041 18.7 4.8 1.1 1 0 0 1 1 1 1 Filament-like plant protein, long coiled-coil ATG16 PF08614.11 CBZ26404.1 - 0.00096 19.4 5.0 0.00096 19.4 5.0 1.9 2 0 0 2 2 2 1 Autophagy protein 16 (ATG16) UBX PF00789.20 CBZ26404.1 - 0.0019 18.4 0.0 0.004 17.3 0.0 1.6 1 0 0 1 1 1 1 UBX domain CALCOCO1 PF07888.11 CBZ26404.1 - 0.0064 15.4 3.9 0.0099 14.8 3.9 1.2 1 0 0 1 1 1 1 Calcium binding and coiled-coil domain (CALCOCO1) like Jnk-SapK_ap_N PF09744.9 CBZ26404.1 - 0.008 16.4 6.0 0.014 15.6 6.0 1.3 1 0 0 1 1 1 1 JNK_SAPK-associated protein-1 APG6_N PF17675.1 CBZ26404.1 - 0.015 15.8 11.1 0.033 14.7 11.1 1.5 1 0 0 1 1 1 0 Apg6 coiled-coil region OmpH PF03938.14 CBZ26404.1 - 0.022 15.1 4.7 0.046 14.1 4.7 1.5 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Spc24 PF08286.11 CBZ26404.1 - 0.028 14.7 3.4 0.061 13.6 3.4 1.6 1 0 0 1 1 1 0 Spc24 subunit of Ndc80 Fmp27_WPPW PF10359.9 CBZ26404.1 - 0.031 13.2 2.1 0.044 12.6 2.1 1.1 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain tRNA-synt_1d PF00750.19 CBZ26404.1 - 0.05 12.5 0.9 0.075 12.0 0.9 1.1 1 0 0 1 1 1 0 tRNA synthetases class I (R) TPR_MLP1_2 PF07926.12 CBZ26404.1 - 0.11 12.6 14.9 0.033 14.2 11.0 2.0 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein ubiquitin PF00240.23 CBZ26404.1 - 0.11 12.2 0.0 0.59 9.9 0.0 2.2 2 0 0 2 2 2 0 Ubiquitin family DUF4482 PF14818.6 CBZ26404.1 - 0.12 13.2 3.2 0.12 13.3 1.3 2.0 2 0 0 2 2 1 0 Domain of unknown function (DUF4482) Golgin_A5 PF09787.9 CBZ26404.1 - 0.14 11.6 5.5 0.24 10.8 5.5 1.3 1 0 0 1 1 1 0 Golgin subfamily A member 5 DUF4407 PF14362.6 CBZ26404.1 - 0.14 11.5 5.2 0.12 11.7 3.9 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) DUF664 PF04978.12 CBZ26404.1 - 0.14 12.6 1.9 0.39 11.1 0.1 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF664) Cep57_MT_bd PF06657.13 CBZ26404.1 - 0.21 12.0 7.5 0.32 11.5 5.9 2.0 1 1 1 2 2 2 0 Centrosome microtubule-binding domain of Cep57 LCD1 PF09798.9 CBZ26404.1 - 0.24 9.8 2.1 0.32 9.5 2.1 1.1 1 0 0 1 1 1 0 DNA damage checkpoint protein TMF_TATA_bd PF12325.8 CBZ26404.1 - 0.26 11.5 8.2 3.9 7.7 8.1 2.2 1 1 0 1 1 1 0 TATA element modulatory factor 1 TATA binding FapA PF03961.13 CBZ26404.1 - 0.33 9.5 2.1 0.51 8.9 2.1 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A Laminin_II PF06009.12 CBZ26404.1 - 2.4 8.2 5.2 1.1 9.2 1.8 1.9 2 0 0 2 2 2 0 Laminin Domain II DAO PF01266.24 CBZ26406.1 - 2.4e-44 152.4 0.0 3.1e-44 152.0 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 CBZ26406.1 - 0.00066 19.9 0.1 0.0016 18.6 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 CBZ26406.1 - 0.0012 18.1 0.3 0.0028 17.0 0.2 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 CBZ26406.1 - 0.0063 15.8 0.4 0.2 10.9 0.1 2.2 2 0 0 2 2 2 1 FAD binding domain Thi4 PF01946.17 CBZ26406.1 - 0.0069 15.7 0.3 0.022 14.0 0.0 2.0 3 0 0 3 3 3 1 Thi4 family TrkA_N PF02254.18 CBZ26406.1 - 0.0098 16.1 0.1 0.039 14.2 0.1 2.0 2 0 0 2 2 2 1 TrkA-N domain Mqo PF06039.15 CBZ26406.1 - 0.011 14.4 0.0 0.042 12.4 0.0 1.9 2 0 0 2 2 2 0 Malate:quinone oxidoreductase (Mqo) Pyr_redox PF00070.27 CBZ26406.1 - 0.078 13.6 0.1 0.2 12.2 0.1 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 CBZ26406.1 - 0.11 11.6 0.1 0.21 10.6 0.1 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein Beta_propel PF09826.9 CBZ26408.1 - 0.084 11.7 2.9 0.1 11.5 0.2 1.8 1 1 1 2 2 2 0 Beta propeller domain DUF1363 PF07101.11 CBZ26409.1 - 0.056 13.7 0.0 0.12 12.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1363) HlyIII PF03006.20 CBZ26410.1 - 2.1e-50 171.5 23.7 2.8e-50 171.1 23.7 1.1 1 0 0 1 1 1 1 Haemolysin-III related DUF962 PF06127.11 CBZ26410.1 - 0.041 14.0 3.4 0.092 12.8 1.4 2.7 1 1 0 1 1 1 0 Protein of unknown function (DUF962) HlyIII PF03006.20 CBZ26411.1 - 2e-49 168.4 26.6 2.5e-49 168.0 26.6 1.1 1 0 0 1 1 1 1 Haemolysin-III related DUF962 PF06127.11 CBZ26411.1 - 0.037 14.1 2.6 0.13 12.4 0.3 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF962) HlyIII PF03006.20 CBZ26412.1 - 4.7e-54 183.5 27.0 6.1e-54 183.1 27.0 1.1 1 0 0 1 1 1 1 Haemolysin-III related PCIF1_WW PF12237.8 CBZ26413.1 - 3.5e-30 104.9 0.6 1.6e-19 70.1 0.3 2.3 2 0 0 2 2 2 2 Phosphorylated CTD interacting factor 1 WW domain AAA_33 PF13671.6 CBZ26414.1 - 5.4e-05 23.4 4.9 0.00021 21.5 0.3 2.8 2 1 0 2 2 2 1 AAA domain KTI12 PF08433.10 CBZ26414.1 - 0.0041 16.6 0.0 0.5 9.8 0.0 2.5 2 1 0 2 2 2 2 Chromatin associated protein KTI12 AAA_16 PF13191.6 CBZ26414.1 - 0.029 14.8 0.1 0.029 14.8 0.1 2.7 2 2 0 2 2 2 0 AAA ATPase domain DUF2065 PF09838.9 CBZ26414.1 - 0.24 11.5 0.5 0.78 9.8 0.5 1.9 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2065) Peptidase_M24 PF00557.24 CBZ26416.1 - 2.8e-35 121.9 0.0 5.5e-35 121.0 0.0 1.5 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.16 CBZ26416.1 - 4.2e-08 33.0 0.0 9.2e-08 31.9 0.0 1.7 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain Peptidase_C27 PF05407.12 CBZ26416.1 - 0.099 12.7 2.5 0.16 12.0 0.3 2.2 2 0 0 2 2 2 0 Rubella virus endopeptidase EMP24_GP25L PF01105.24 CBZ26417.1 - 1.5e-11 44.6 0.0 1.9e-11 44.2 0.0 1.3 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD HrpB2 PF09487.10 CBZ26418.1 - 0.00078 19.9 0.0 0.0023 18.4 0.0 1.7 2 0 0 2 2 2 1 Bacterial type III secretion protein (HrpB2) NERD PF08378.11 CBZ26420.1 - 7.1e-17 61.8 0.3 2e-16 60.4 0.3 1.8 1 1 0 1 1 1 1 Nuclease-related domain UPF0102 PF02021.17 CBZ26420.1 - 0.00041 20.5 0.1 0.0012 19.0 0.1 1.8 1 0 0 1 1 1 1 Uncharacterised protein family UPF0102 tRNA-synt_1 PF00133.22 CBZ26421.1 - 4.1e-214 712.3 3.3 1.4e-213 710.5 0.1 2.7 2 1 0 2 2 2 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 CBZ26421.1 - 5e-21 75.2 0.1 1.5e-20 73.7 0.0 1.9 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 CBZ26421.1 - 5.9e-13 48.3 2.3 0.00098 18.0 0.3 3.9 3 1 0 3 3 3 3 tRNA synthetases class I (M) tRNA-synt_1e PF01406.19 CBZ26421.1 - 0.003 16.9 0.6 0.14 11.4 0.0 3.1 2 1 0 2 2 2 1 tRNA synthetases class I (C) catalytic domain SWIM PF04434.17 CBZ26422.1 - 0.084 12.6 1.4 0.2 11.4 1.4 1.6 1 0 0 1 1 1 0 SWIM zinc finger Cyclin_N PF00134.23 CBZ26423.1 - 0.0007 19.3 0.1 0.0052 16.5 0.0 2.2 2 0 0 2 2 2 1 Cyclin, N-terminal domain BT1 PF03092.16 CBZ26424.1 - 0.51 8.5 3.2 0.6 8.3 0.7 2.0 2 0 0 2 2 2 0 BT1 family DAO PF01266.24 CBZ26425.1 - 3.8e-18 66.2 2.2 5.1e-11 42.8 0.8 3.3 2 1 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 CBZ26425.1 - 7.6e-08 32.5 0.5 3.3e-07 30.4 0.7 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 CBZ26425.1 - 4e-06 26.3 0.1 7.9e-05 22.0 0.1 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 CBZ26425.1 - 2.1e-05 25.0 1.6 4.2e-05 24.0 1.0 1.8 2 0 0 2 2 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 CBZ26425.1 - 0.0003 20.1 0.1 0.00065 19.0 0.1 1.5 1 0 0 1 1 1 1 Thi4 family FAD_binding_2 PF00890.24 CBZ26425.1 - 0.0019 17.4 0.7 0.0031 16.6 0.7 1.3 1 0 0 1 1 1 1 FAD binding domain GIDA PF01134.22 CBZ26425.1 - 0.0029 16.8 0.8 0.0046 16.1 0.8 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A 3HCDH_N PF02737.18 CBZ26425.1 - 0.022 14.6 0.7 0.052 13.4 0.7 1.6 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 CBZ26425.1 - 0.025 13.9 0.4 0.044 13.1 0.4 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain HI0933_like PF03486.14 CBZ26425.1 - 0.03 13.0 0.5 0.046 12.4 0.5 1.2 1 0 0 1 1 1 0 HI0933-like protein FAD_binding_3 PF01494.19 CBZ26425.1 - 0.032 13.5 0.3 0.069 12.4 0.3 1.4 1 0 0 1 1 1 0 FAD binding domain Pyr_redox_3 PF13738.6 CBZ26425.1 - 0.043 13.1 0.1 0.076 12.3 0.1 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 CBZ26425.1 - 0.066 13.2 0.3 0.18 11.8 0.3 1.7 1 0 0 1 1 1 0 FAD-NAD(P)-binding NolV PF06635.12 CBZ26425.1 - 0.081 12.3 0.3 0.17 11.3 0.3 1.4 1 0 0 1 1 1 0 Nodulation protein NolV FAD_oxidored PF12831.7 CBZ26425.1 - 1.8 7.8 4.7 0.88 8.8 1.0 2.1 3 0 0 3 3 3 0 FAD dependent oxidoreductase HA2 PF04408.23 CBZ26426.1 - 8.2e-15 55.0 0.5 2.2e-14 53.6 0.4 1.8 1 1 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 CBZ26426.1 - 1.5e-14 54.1 0.0 3.8e-14 52.8 0.0 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 CBZ26426.1 - 1.9e-13 50.7 0.0 4.8e-13 49.4 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 CBZ26426.1 - 1.2e-09 38.2 0.0 2.1e-09 37.4 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 CBZ26426.1 - 7.5e-05 23.0 0.0 0.00029 21.1 0.0 2.0 2 0 0 2 2 2 1 AAA domain PhoH PF02562.16 CBZ26426.1 - 0.0078 15.7 0.2 0.066 12.7 0.0 2.6 3 0 0 3 3 3 1 PhoH-like protein AAA_19 PF13245.6 CBZ26426.1 - 0.012 16.0 0.4 0.1 13.0 0.0 2.6 3 0 0 3 3 3 0 AAA domain Kringle PF00051.18 CBZ26426.1 - 0.022 15.0 0.0 0.043 14.1 0.0 1.4 1 0 0 1 1 1 0 Kringle domain T2SSE PF00437.20 CBZ26426.1 - 0.025 13.6 0.0 0.057 12.5 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_7 PF12775.7 CBZ26426.1 - 0.027 14.0 0.0 0.056 13.0 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region ResIII PF04851.15 CBZ26426.1 - 0.037 14.0 0.0 11 6.0 0.0 2.4 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit AAA_30 PF13604.6 CBZ26426.1 - 0.061 13.0 0.0 0.12 12.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain ATPase PF06745.13 CBZ26426.1 - 0.069 12.5 0.0 0.15 11.4 0.0 1.5 1 0 0 1 1 1 0 KaiC CUE PF02845.16 CBZ26429.1 - 0.00051 19.7 0.0 0.014 15.0 0.0 2.8 3 0 0 3 3 3 1 CUE domain Cullin_binding PF03556.15 CBZ26430.1 - 1.3e-20 74.0 2.1 2.5e-20 73.1 2.1 1.4 1 0 0 1 1 1 1 Cullin binding DUF1685 PF07939.11 CBZ26432.1 - 0.16 11.7 0.0 12 5.8 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1685) TruD PF01142.18 CBZ26434.1 - 3e-60 204.2 0.0 5.1e-54 183.7 0.0 2.7 3 0 0 3 3 3 2 tRNA pseudouridine synthase D (TruD) RAB3GAP2_N PF14655.6 CBZ26435.1 - 3.4e-12 46.3 0.7 5e-12 45.8 0.1 1.5 2 0 0 2 2 2 1 Rab3 GTPase-activating protein regulatory subunit N-terminus MS_channel PF00924.18 CBZ26436.1 - 2.2e-18 66.5 1.3 2.7e-18 66.3 1.3 1.1 1 0 0 1 1 1 1 Mechanosensitive ion channel Gcd10p PF04189.13 CBZ26437.1 - 9e-49 166.2 0.0 1.3e-48 165.7 0.0 1.2 1 0 0 1 1 1 1 Gcd10p family LRR_8 PF13855.6 CBZ26438.1 - 7.2e-07 28.9 0.0 9.1e-06 25.4 0.0 2.3 1 1 2 3 3 3 2 Leucine rich repeat LRR_4 PF12799.7 CBZ26438.1 - 9.3e-06 25.9 1.5 0.001 19.4 0.4 3.0 1 1 2 3 3 3 2 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 CBZ26438.1 - 0.00014 21.4 0.0 0.00032 20.2 0.0 1.7 1 1 0 1 1 1 1 Leucine-rich repeat TMEM100 PF16311.5 CBZ26438.1 - 0.004 16.8 0.3 0.0087 15.7 0.3 1.6 1 0 0 1 1 1 1 Transmembrane protein 100 DUF383 PF04063.14 CBZ26439.1 - 0.035 13.8 0.0 6.4 6.4 0.0 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF383) DUF945 PF06097.11 CBZ26440.1 - 0.13 11.4 0.1 0.19 10.8 0.1 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF945) Nitroreductase PF00881.24 CBZ26442.1 - 7.2e-13 48.9 0.2 8.8e-13 48.7 0.2 1.1 1 0 0 1 1 1 1 Nitroreductase family HMG_box_2 PF09011.10 CBZ26444.1 - 1.6e-06 28.6 1.8 0.01 16.4 0.2 2.5 2 1 0 2 2 2 2 HMG-box domain YABBY PF04690.13 CBZ26444.1 - 3.5e-05 24.4 0.8 4.2e-05 24.2 0.8 1.1 1 0 0 1 1 1 1 YABBY protein DUF3106 PF11304.8 CBZ26444.1 - 0.017 15.6 1.0 0.076 13.5 0.4 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3106) HMG_box PF00505.19 CBZ26444.1 - 0.023 15.1 5.1 0.45 11.0 1.0 3.0 2 2 0 2 2 2 0 HMG (high mobility group) box S1FA PF04689.13 CBZ26444.1 - 0.11 12.7 0.1 0.11 12.7 0.1 2.0 2 0 0 2 2 2 0 DNA binding protein S1FA Ribosomal_L6 PF00347.23 CBZ26444.1 - 0.12 13.0 0.1 0.17 12.6 0.1 1.3 1 0 0 1 1 1 0 Ribosomal protein L6 AAA PF00004.29 CBZ26446.1 - 3e-11 43.9 0.0 0.00019 21.8 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 CBZ26446.1 - 6e-05 23.1 0.0 0.00013 22.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 CBZ26446.1 - 0.0025 18.2 1.2 0.016 15.6 0.1 2.7 2 1 0 2 2 2 1 AAA ATPase domain DUF815 PF05673.13 CBZ26446.1 - 0.0065 15.7 0.0 0.014 14.5 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_7 PF12775.7 CBZ26446.1 - 0.036 13.6 0.0 0.089 12.3 0.0 1.6 1 0 0 1 1 1 0 P-loop containing dynein motor region NICE-1 PF15845.5 CBZ26447.1 - 3.1 8.6 6.3 16 6.3 0.2 2.9 2 0 0 2 2 2 0 Cysteine-rich C-terminal 1 family Gtr1_RagA PF04670.12 CBZ26448.1 - 2.4e-67 226.7 0.4 3.1e-67 226.3 0.4 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 CBZ26448.1 - 4e-07 30.1 0.0 9.1e-07 29.0 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase Arf PF00025.21 CBZ26448.1 - 9.2e-06 25.2 0.0 1.8e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 CBZ26448.1 - 1.1e-05 25.7 0.0 2.6e-05 24.4 0.0 1.8 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 CBZ26448.1 - 0.0096 15.5 0.0 0.014 15.0 0.0 1.4 1 0 0 1 1 1 1 Ras family SRPRB PF09439.10 CBZ26448.1 - 0.011 15.2 0.0 0.028 13.9 0.0 1.6 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit YliH PF10799.8 CBZ26448.1 - 0.013 15.4 0.5 0.032 14.2 0.0 1.9 2 0 0 2 2 2 0 Biofilm formation protein (YliH/bssR) ATP_bind_1 PF03029.17 CBZ26448.1 - 0.02 14.7 0.2 0.033 14.0 0.2 1.4 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein DUF910 PF06014.11 CBZ26448.1 - 0.089 12.8 0.0 0.29 11.2 0.0 1.9 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF910) TyeA PF09059.10 CBZ26449.1 - 0.12 12.5 0.4 1.2 9.3 0.0 2.5 2 0 0 2 2 2 0 TyeA CDP-OH_P_transf PF01066.21 CBZ26450.1 - 1.2e-17 64.4 0.1 1.2e-17 64.4 0.1 3.9 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase Lge1 PF11488.8 CBZ26452.1 - 0.023 14.9 0.0 0.055 13.6 0.0 1.6 1 0 0 1 1 1 0 Transcriptional regulatory protein LGE1 DUF642 PF04862.12 CBZ26452.1 - 0.11 12.3 0.2 0.16 11.7 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF642) Taxilin PF09728.9 CBZ26453.1 - 1.7e-06 27.5 54.0 2e-06 27.3 54.0 1.1 1 0 0 1 1 1 1 Myosin-like coiled-coil protein DUF3015 PF11220.8 CBZ26453.1 - 5.5 6.8 7.0 4.4 7.2 0.9 2.8 3 1 1 4 4 4 0 Protein of unknown function (DUF3015) KxDL PF10241.9 CBZ26453.1 - 8.3 6.8 29.1 1 9.7 4.2 4.2 1 1 2 4 4 4 0 Uncharacterized conserved protein LmjF365940-deam PF14421.6 CBZ26454.1 - 2.8e-41 141.2 0.0 2.1e-21 76.4 0.0 2.3 1 1 1 2 2 2 2 A distinct subfamily of CDD/CDA-like deaminases DUF3105 PF11303.8 CBZ26454.1 - 0.089 12.9 0.0 0.2 11.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3105) DUF5567 PF17722.1 CBZ26455.1 - 4.4e-05 23.5 0.5 0.2 11.5 0.1 2.8 2 1 1 3 3 3 2 Family of unknown function (DUF5567) Ead_Ea22 PF13935.6 CBZ26455.1 - 0.061 14.0 0.6 0.1 13.2 0.6 1.4 1 0 0 1 1 1 0 Ead/Ea22-like protein DUF4996 PF16387.5 CBZ26456.1 - 1.3e-31 109.0 0.2 4.6e-31 107.3 0.1 1.9 2 1 0 2 2 2 1 Domain of unknown function GDPD PF03009.17 CBZ26456.1 - 5.9e-23 81.9 0.2 1.3e-22 80.8 0.1 1.6 2 0 0 2 2 2 1 Glycerophosphoryl diester phosphodiesterase family PI-PLC-X PF00388.19 CBZ26456.1 - 0.009 15.6 0.1 0.017 14.7 0.1 1.4 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain DUF2207 PF09972.9 CBZ26457.1 - 0.011 14.6 7.6 0.51 9.0 0.2 2.5 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) DUF3974 PF13120.6 CBZ26457.1 - 0.054 13.6 0.8 2.2 8.4 0.0 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF3974) Ninjurin PF04923.12 CBZ26457.1 - 0.074 13.0 4.3 5.6 6.9 0.0 2.4 2 0 0 2 2 2 0 Ninjurin Chordopox_A13L PF05961.11 CBZ26457.1 - 0.11 12.7 0.6 1.7 8.9 0.0 2.6 2 0 0 2 2 2 0 Chordopoxvirus A13L protein DUF3311 PF11755.8 CBZ26457.1 - 0.17 11.8 0.2 0.17 11.8 0.2 3.3 4 0 0 4 4 4 0 Protein of unknown function (DUF3311) EphA2_TM PF14575.6 CBZ26457.1 - 0.23 12.3 5.9 0.68 10.9 0.0 3.3 3 0 0 3 3 3 0 Ephrin type-A receptor 2 transmembrane domain Tmemb_185A PF10269.9 CBZ26457.1 - 0.6 9.8 16.3 0.09 12.5 0.6 2.4 1 1 0 2 2 2 0 Transmembrane Fragile-X-F protein RRM_1 PF00076.22 CBZ26458.1 - 0.024 14.4 0.0 0.053 13.3 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Macoilin PF09726.9 CBZ26458.1 - 0.72 8.3 4.5 1.2 7.5 4.5 1.4 1 0 0 1 1 1 0 Macoilin family SpoV PF08183.11 CBZ26459.1 - 1.3e-05 25.0 0.0 2.1e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 Stage V sporulation protein family Glyco_hydro_3_C PF01915.22 CBZ26460.1 - 0.17 11.8 4.7 1.2 9.1 0.1 2.6 1 1 1 2 2 2 0 Glycosyl hydrolase family 3 C-terminal domain MotY_N PF18393.1 CBZ26460.1 - 0.22 11.7 3.2 3.1 7.9 0.4 3.2 2 0 0 2 2 2 0 MotY N-terminal domain Trimer_CC PF08954.11 CBZ26460.1 - 0.59 9.7 9.2 5.2 6.7 1.2 3.3 2 0 0 2 2 2 0 Trimerisation motif OTU PF02338.19 CBZ26462.1 - 9.5e-05 22.9 0.0 0.00017 22.1 0.0 1.4 1 0 0 1 1 1 1 OTU-like cysteine protease FAP206 PF12018.8 CBZ26463.1 - 1.2e-11 44.6 0.2 0.00045 19.8 0.0 5.0 5 0 0 5 5 5 3 Domain of unknown function AAA_33 PF13671.6 CBZ26463.1 - 6e-06 26.5 5.3 0.0024 18.0 0.0 4.8 4 0 0 4 4 4 1 AAA domain YHS PF04945.13 CBZ26463.1 - 1.7e-05 24.8 2.0 0.062 13.4 0.2 3.9 4 0 0 4 4 4 2 YHS domain AAA_18 PF13238.6 CBZ26463.1 - 0.00097 19.7 0.0 0.031 14.8 0.0 3.2 2 0 0 2 2 2 1 AAA domain ADK PF00406.22 CBZ26463.1 - 0.0016 18.5 0.0 0.0092 16.1 0.0 2.3 2 0 0 2 2 2 1 Adenylate kinase AAA_17 PF13207.6 CBZ26463.1 - 0.0047 17.3 8.5 0.026 15.0 0.0 4.0 4 1 0 4 4 4 2 AAA domain AAA PF00004.29 CBZ26463.1 - 0.0064 16.9 0.0 0.019 15.4 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 CBZ26463.1 - 0.0074 16.7 10.2 0.091 13.1 4.6 4.9 3 1 0 3 3 3 1 AAA ATPase domain AAA_5 PF07728.14 CBZ26463.1 - 0.12 12.4 0.5 0.73 9.8 0.0 2.6 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) COG2 PF06148.11 CBZ26464.1 - 1.1e-44 151.7 0.0 2.9e-44 150.4 0.0 1.8 1 0 0 1 1 1 1 COG (conserved oligomeric Golgi) complex component, COG2 DUF3510 PF12022.8 CBZ26464.1 - 1.1e-30 106.6 0.2 4.5e-30 104.6 0.2 2.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3510) MIF4G PF02854.19 CBZ26466.1 - 1.8e-21 76.8 0.0 4e-21 75.6 0.0 1.6 1 0 0 1 1 1 1 MIF4G domain RabGAP-TBC PF00566.18 CBZ26467.1 - 1.8e-57 194.5 0.0 2.3e-57 194.1 0.0 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain CBP_BcsF PF11120.8 CBZ26467.1 - 0.97 9.6 2.7 2.9 8.1 0.3 2.4 2 0 0 2 2 2 0 Cellulose biosynthesis protein BcsF RabGAP-TBC PF00566.18 CBZ26468.1 - 7.3e-59 199.0 0.1 9.7e-59 198.6 0.1 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain ABC1 PF03109.16 CBZ26469.1 - 1.3e-28 99.6 0.0 3e-28 98.4 0.0 1.6 1 0 0 1 1 1 1 ABC1 family Pkinase PF00069.25 CBZ26469.1 - 1.9e-07 30.7 0.1 0.0049 16.3 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ26469.1 - 2e-06 27.3 0.1 0.0094 15.3 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase RIO1 PF01163.22 CBZ26469.1 - 0.00013 21.6 0.1 0.00084 19.0 0.0 2.0 2 0 0 2 2 2 1 RIO1 family APH PF01636.23 CBZ26469.1 - 0.00016 21.6 0.0 0.0003 20.8 0.0 1.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family CRISPR_Cas6 PF10040.9 CBZ26469.1 - 0.035 14.7 0.0 0.4 11.4 0.0 2.4 2 0 0 2 2 2 0 CRISPR-associated endoribonuclease Cas6 CagD PF16567.5 CBZ26469.1 - 0.038 13.8 0.8 0.1 12.4 0.2 1.9 2 0 0 2 2 2 0 Pathogenicity island component CagD NanE PF04131.14 CBZ26469.1 - 0.12 11.5 0.0 0.23 10.6 0.0 1.4 1 0 0 1 1 1 0 Putative N-acetylmannosamine-6-phosphate epimerase UBM PF14377.6 CBZ26469.1 - 2.5 7.7 5.8 0.55 9.8 0.9 2.5 2 0 0 2 2 2 0 Ubiquitin binding region TPR_19 PF14559.6 CBZ26470.1 - 0.0045 17.5 14.4 1.2 9.7 2.0 5.2 5 1 0 5 5 5 3 Tetratricopeptide repeat TPR_2 PF07719.17 CBZ26470.1 - 0.014 15.5 15.2 7.9 6.9 0.2 6.2 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_16 PF13432.6 CBZ26470.1 - 0.014 16.0 22.5 3.5 8.3 0.6 5.8 5 1 1 6 6 6 0 Tetratricopeptide repeat ANAPC3 PF12895.7 CBZ26470.1 - 0.024 14.8 13.7 0.48 10.7 0.6 4.9 4 1 1 5 5 5 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.6 CBZ26470.1 - 0.029 15.2 17.4 2 9.4 0.2 5.8 4 2 2 6 6 6 0 Tetratricopeptide repeat HrpB1_HrpK PF09613.10 CBZ26470.1 - 0.049 13.3 2.6 0.3 10.7 0.0 3.4 4 0 0 4 4 4 0 Bacterial type III secretion protein (HrpB1_HrpK) PPR PF01535.20 CBZ26470.1 - 0.093 13.0 0.2 14 6.2 0.0 3.0 2 0 0 2 2 2 0 PPR repeat EF-hand_7 PF13499.6 CBZ26471.1 - 1.7e-14 54.0 2.9 1.9e-06 28.2 0.0 2.5 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 CBZ26471.1 - 7.7e-09 34.8 2.3 0.0022 17.8 0.0 4.2 4 1 0 4 4 4 2 EF-hand domain EF-hand_1 PF00036.32 CBZ26471.1 - 3.2e-08 32.5 1.8 0.012 15.1 0.0 4.6 4 1 0 4 4 4 2 EF hand EF-hand_8 PF13833.6 CBZ26471.1 - 6.7e-08 32.3 0.3 0.0093 15.8 0.3 2.8 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_9 PF14658.6 CBZ26471.1 - 7.5e-06 26.2 0.1 0.002 18.4 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 CBZ26471.1 - 0.036 13.6 0.3 3.4 7.3 0.1 3.3 3 0 0 3 3 3 0 EF hand ATP_bind_3 PF01171.20 CBZ26472.1 - 9e-17 61.4 0.0 1.5e-16 60.6 0.0 1.3 1 1 0 1 1 1 1 PP-loop family zn-ribbon_14 PF16503.5 CBZ26472.1 - 3.4e-11 42.5 5.3 3.4e-11 42.5 5.3 4.0 4 0 0 4 4 4 1 Zinc-ribbon tRNA_Me_trans PF03054.16 CBZ26472.1 - 0.094 11.5 0.0 0.2 10.4 0.0 1.5 1 1 0 1 1 1 0 tRNA methyl transferase TF_Zn_Ribbon PF08271.12 CBZ26472.1 - 0.12 11.9 2.3 0.31 10.6 0.2 2.5 2 0 0 2 2 2 0 TFIIB zinc-binding PAPS_reduct PF01507.19 CBZ26472.1 - 0.16 12.0 0.0 0.26 11.3 0.0 1.4 1 1 0 1 1 1 0 Phosphoadenosine phosphosulfate reductase family S1-P1_nuclease PF02265.16 CBZ26473.1 - 0.00058 19.8 0.6 0.0014 18.5 0.3 1.7 1 1 1 2 2 2 1 S1/P1 Nuclease Rab5-bind PF09311.11 CBZ26473.1 - 0.058 12.8 4.9 0.023 14.1 1.5 1.8 2 0 0 2 2 2 0 Rabaptin-like protein RdRP PF05183.12 CBZ26473.1 - 0.064 11.9 0.7 0.092 11.4 0.7 1.2 1 0 0 1 1 1 0 RNA dependent RNA polymerase TBD PF12845.7 CBZ26473.1 - 0.14 12.0 1.6 0.48 10.4 1.6 1.8 1 0 0 1 1 1 0 TBD domain Fis1_TPR_C PF14853.6 CBZ26475.1 - 0.00021 21.3 0.5 0.00051 20.1 0.5 1.7 1 0 0 1 1 1 1 Fis1 C-terminal tetratricopeptide repeat TPR_1 PF00515.28 CBZ26475.1 - 0.0058 16.4 0.1 0.013 15.3 0.1 1.6 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_2 PF07719.17 CBZ26475.1 - 0.13 12.4 0.1 0.33 11.2 0.1 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat MAGE_N PF12440.8 CBZ26475.1 - 9.7 7.0 8.1 14 6.5 6.9 1.9 1 1 0 1 1 1 0 Melanoma associated antigen family N terminal Ran_BP1 PF00638.18 CBZ26476.1 - 0.0026 18.0 0.0 0.0052 17.0 0.0 1.5 1 1 0 1 1 1 1 RanBP1 domain Kelch_5 PF13854.6 CBZ26477.1 - 1.3e-14 53.8 0.4 0.015 15.2 0.0 5.7 6 0 0 6 6 6 4 Kelch motif Kelch_4 PF13418.6 CBZ26477.1 - 3.2e-12 46.2 6.3 0.067 13.2 0.0 6.5 6 1 0 6 6 6 4 Galactose oxidase, central domain Kelch_3 PF13415.6 CBZ26477.1 - 5.8e-11 42.4 11.4 0.044 14.1 0.0 6.7 6 1 1 7 7 7 4 Galactose oxidase, central domain Kelch_1 PF01344.25 CBZ26477.1 - 8e-11 41.4 0.1 0.00058 19.4 0.1 5.5 6 0 0 6 6 6 3 Kelch motif Kelch_6 PF13964.6 CBZ26477.1 - 1.3e-08 34.9 3.2 0.095 13.0 0.1 5.4 4 1 1 5 5 5 3 Kelch motif Kelch_2 PF07646.15 CBZ26477.1 - 3e-05 23.8 0.3 1.4 9.0 0.3 5.4 5 1 0 5 5 5 1 Kelch motif Suc_Fer-like PF06999.12 CBZ26478.1 - 2.4e-26 92.8 0.0 3.4e-26 92.3 0.0 1.2 1 0 0 1 1 1 1 Sucrase/ferredoxin-like PB1 PF00564.24 CBZ26478.1 - 0.14 12.1 0.0 0.26 11.2 0.0 1.4 1 0 0 1 1 1 0 PB1 domain UL42 PF17638.2 CBZ26479.1 - 0.11 12.4 0.1 0.2 11.7 0.1 1.4 1 0 0 1 1 1 0 HCMV UL42 Fz PF01392.22 CBZ26480.1 - 0.35 11.5 5.6 0.11 13.2 1.6 2.1 2 0 0 2 2 2 0 Fz domain Vps54 PF07928.12 CBZ26481.1 - 1.2e-21 77.6 2.4 4.2e-21 75.8 0.2 2.9 2 1 0 2 2 2 1 Vps54-like protein GCN5L1 PF06320.13 CBZ26481.1 - 0.004 17.3 0.0 0.015 15.5 0.0 2.0 1 0 0 1 1 1 1 GCN5-like protein 1 (GCN5L1) COG2 PF06148.11 CBZ26481.1 - 0.0076 16.3 0.0 0.031 14.4 0.0 2.1 1 0 0 1 1 1 1 COG (conserved oligomeric Golgi) complex component, COG2 Tropomyosin_1 PF12718.7 CBZ26482.1 - 0.15 12.2 23.9 0.045 13.9 2.2 3.4 3 0 0 3 3 3 0 Tropomyosin like Phage_Mu_Gam PF07352.12 CBZ26482.1 - 6.9 6.6 12.6 52 3.7 12.6 2.4 1 1 0 1 1 1 0 Bacteriophage Mu Gam like protein Arf PF00025.21 CBZ26483.1 - 1.2e-60 203.9 0.0 1.4e-60 203.7 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 CBZ26483.1 - 4.7e-13 49.4 0.0 6.5e-13 49.0 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase G-alpha PF00503.20 CBZ26483.1 - 6.9e-13 48.5 0.0 5.2e-10 39.0 0.0 2.4 1 1 1 2 2 2 2 G-protein alpha subunit Ras PF00071.22 CBZ26483.1 - 9.3e-12 44.8 0.0 1.1e-11 44.6 0.0 1.1 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.12 CBZ26483.1 - 2.8e-11 43.2 0.0 3.2e-11 43.0 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 CBZ26483.1 - 1.8e-10 40.9 0.0 3.2e-10 40.1 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 CBZ26483.1 - 4.2e-09 36.1 0.0 5.3e-09 35.8 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.27 CBZ26483.1 - 0.00088 18.9 0.0 0.0023 17.5 0.0 1.7 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MeaB PF03308.16 CBZ26483.1 - 0.0082 15.2 0.1 0.09 11.7 0.1 2.1 1 1 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB FeoB_N PF02421.18 CBZ26483.1 - 0.01 15.4 0.1 0.11 12.0 0.1 2.3 1 1 0 1 1 1 0 Ferrous iron transport protein B TniB PF05621.11 CBZ26483.1 - 0.018 14.5 0.0 0.054 12.9 0.0 1.7 2 0 0 2 2 2 0 Bacterial TniB protein PduV-EutP PF10662.9 CBZ26483.1 - 0.049 13.4 0.1 0.15 11.8 0.1 1.8 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation DSBA PF01323.20 CBZ26483.1 - 0.049 13.4 0.0 0.067 13.0 0.0 1.3 1 0 0 1 1 1 0 DSBA-like thioredoxin domain AAA_18 PF13238.6 CBZ26483.1 - 0.053 14.1 0.0 0.09 13.3 0.0 1.4 1 1 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 CBZ26483.1 - 0.061 13.2 0.0 1.9 8.4 0.0 2.1 2 0 0 2 2 2 0 RsgA GTPase AAA_16 PF13191.6 CBZ26483.1 - 0.065 13.6 0.0 0.093 13.1 0.0 1.3 1 1 0 1 1 1 0 AAA ATPase domain cobW PF02492.19 CBZ26483.1 - 0.084 12.5 0.1 0.63 9.6 0.0 2.0 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Dynamin_N PF00350.23 CBZ26483.1 - 0.12 12.5 0.0 9.5 6.2 0.0 2.1 2 0 0 2 2 2 0 Dynamin family CdhD PF03599.16 CBZ26483.1 - 0.15 10.7 0.0 0.2 10.3 0.0 1.2 1 0 0 1 1 1 0 CO dehydrogenase/acetyl-CoA synthase delta subunit Thioredoxin_2 PF13098.6 CBZ26483.1 - 0.16 12.4 0.0 0.21 12.0 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin-like domain AAA_28 PF13521.6 CBZ26484.1 - 0.0079 16.4 0.1 0.017 15.4 0.1 1.6 1 0 0 1 1 1 1 AAA domain Roc PF08477.13 CBZ26484.1 - 0.084 13.1 0.0 0.19 12.0 0.0 1.6 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase AAA_14 PF13173.6 CBZ26484.1 - 0.13 12.3 0.0 0.24 11.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain Ras PF00071.22 CBZ26485.1 - 9.6e-47 158.6 0.3 1.3e-46 158.2 0.3 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CBZ26485.1 - 9.6e-31 106.5 0.1 1.7e-30 105.7 0.1 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CBZ26485.1 - 1.4e-06 27.9 0.1 1.8e-06 27.5 0.1 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 CBZ26485.1 - 0.0035 17.4 0.1 0.0094 16.0 0.0 1.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 CBZ26485.1 - 0.033 13.5 0.2 0.16 11.3 0.0 2.0 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region FeoB_N PF02421.18 CBZ26485.1 - 0.094 12.2 0.1 8.9 5.8 0.0 2.4 2 0 0 2 2 2 0 Ferrous iron transport protein B TniB PF05621.11 CBZ26485.1 - 0.13 11.7 0.0 0.32 10.4 0.0 1.6 2 0 0 2 2 2 0 Bacterial TniB protein SRP-alpha_N PF04086.13 CBZ26485.1 - 5.4 6.9 10.1 9 6.1 10.1 1.3 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal DnaJ_C PF01556.18 CBZ26487.1 - 1.8e-35 122.2 0.0 2.4e-35 121.8 0.0 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 CBZ26487.1 - 2.2e-27 95.0 6.1 3.4e-27 94.4 6.1 1.3 1 0 0 1 1 1 1 DnaJ domain DUF643 PF04867.12 CBZ26487.1 - 0.05 14.2 0.2 0.51 11.0 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF643) Sugar_tr PF00083.24 CBZ26488.1 - 1.1e-99 334.3 36.7 4.4e-59 200.5 15.8 2.1 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 CBZ26488.1 - 4.5e-17 62.0 33.1 1.4e-15 57.1 30.2 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF3522 PF12036.8 CBZ26488.1 - 0.27 11.5 0.1 0.27 11.5 0.1 3.2 4 0 0 4 4 4 0 Protein of unknown function (DUF3522) DUF1430 PF07242.11 CBZ26488.1 - 0.51 10.6 0.0 0.51 10.6 0.0 3.2 4 0 0 4 4 4 0 Protein of unknown function (DUF1430) Sugar_tr PF00083.24 CBZ26489.1 - 1.7e-99 333.8 36.7 9.1e-59 199.5 16.0 2.1 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 CBZ26489.1 - 2e-16 59.9 34.7 3.4e-15 55.8 31.9 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF4064 PF13273.6 CBZ26489.1 - 0.041 14.2 0.8 0.041 14.2 0.8 5.3 5 2 0 5 5 5 0 Protein of unknown function (DUF4064) DUF1430 PF07242.11 CBZ26489.1 - 0.51 10.6 0.0 0.51 10.6 0.0 3.2 4 0 0 4 4 4 0 Protein of unknown function (DUF1430) Sugar_tr PF00083.24 CBZ26490.1 - 4.9e-99 332.2 36.7 5.3e-59 200.3 15.5 2.1 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 CBZ26490.1 - 1.5e-16 60.2 53.3 4.8e-15 55.3 31.5 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF4064 PF13273.6 CBZ26490.1 - 0.045 14.0 0.8 0.045 14.0 0.8 5.4 5 2 0 5 5 5 0 Protein of unknown function (DUF4064) DUF1430 PF07242.11 CBZ26490.1 - 0.56 10.5 0.0 0.56 10.5 0.0 3.1 4 0 0 4 4 4 0 Protein of unknown function (DUF1430) S-methyl_trans PF02574.16 CBZ26491.1 - 4.8e-71 239.7 0.1 5.4e-71 239.5 0.1 1.0 1 0 0 1 1 1 1 Homocysteine S-methyltransferase Kelch_1 PF01344.25 CBZ26491.1 - 0.0071 15.9 0.6 0.017 14.7 0.1 1.9 2 0 0 2 2 2 1 Kelch motif HEPN_SAV_6107 PF18726.1 CBZ26491.1 - 0.039 14.5 0.4 0.13 12.7 0.4 1.9 1 0 0 1 1 1 0 SAV_6107-like HEPN PI3_PI4_kinase PF00454.27 CBZ26492.1 - 2.1e-63 214.4 0.0 3.9e-63 213.6 0.0 1.5 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FAT PF02259.23 CBZ26492.1 - 7e-54 183.3 0.1 1.9e-53 181.9 0.1 1.8 1 0 0 1 1 1 1 FAT domain DUF3385 PF11865.8 CBZ26492.1 - 2.9e-22 79.3 1.3 3e-20 72.8 0.0 4.3 4 1 1 5 5 5 1 Domain of unknown function (DUF3385) FRB_dom PF08771.11 CBZ26492.1 - 3.8e-21 75.4 0.2 2e-20 73.0 0.2 2.4 1 0 0 1 1 1 1 FKBP12-rapamycin binding domain FATC PF02260.20 CBZ26492.1 - 5.4e-16 58.1 0.2 1.3e-15 56.9 0.2 1.7 1 0 0 1 1 1 1 FATC domain HEAT_2 PF13646.6 CBZ26492.1 - 6e-06 26.6 8.4 0.25 11.7 0.1 6.5 7 0 0 7 7 7 2 HEAT repeats IFRD PF05004.13 CBZ26492.1 - 0.046 12.8 0.0 2.1 7.4 0.0 2.6 2 0 0 2 2 2 0 Interferon-related developmental regulator (IFRD) HEAT PF02985.22 CBZ26492.1 - 0.52 10.7 10.4 30 5.2 0.1 7.3 6 0 0 6 6 6 0 HEAT repeat PEX11 PF05648.14 CBZ26493.1 - 0.0081 15.6 0.0 0.014 14.9 0.0 1.4 1 0 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) HECT PF00632.25 CBZ26494.1 - 1.8e-53 182.0 0.0 2.9e-53 181.3 0.0 1.3 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) SPRY PF00622.28 CBZ26494.1 - 4.1e-38 130.2 0.0 2.6e-15 56.6 0.0 4.4 4 0 0 4 4 4 3 SPRY domain Laminin_G_3 PF13385.6 CBZ26494.1 - 5e-17 62.5 0.0 1.5e-08 34.9 0.0 3.9 4 0 0 4 4 4 2 Concanavalin A-like lectin/glucanases superfamily Pox_MCEL PF03291.16 CBZ26495.1 - 0.025 13.7 0.0 0.033 13.3 0.0 1.2 1 0 0 1 1 1 0 mRNA capping enzyme PH_11 PF15413.6 CBZ26496.1 - 0.0016 18.8 0.0 0.003 17.9 0.0 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain Syntaxin-6_N PF09177.11 CBZ26496.1 - 0.097 13.2 0.7 0.45 11.1 0.1 2.2 2 1 0 2 2 2 0 Syntaxin 6, N-terminal CAF1 PF04857.20 CBZ26497.1 - 1.3e-67 228.3 0.2 1.6e-67 227.9 0.2 1.1 1 0 0 1 1 1 1 CAF1 family ribonuclease Tma16 PF11176.8 CBZ26498.1 - 4.2e-23 81.8 0.1 4.2e-23 81.8 0.1 1.8 2 0 0 2 2 2 1 Translation machinery-associated protein 16 RabGAP-TBC PF00566.18 CBZ26499.1 - 8.1e-14 51.8 0.5 1.2e-13 51.2 0.5 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain ArfGap PF01412.18 CBZ26499.1 - 0.087 12.9 0.2 0.28 11.3 0.2 1.8 1 0 0 1 1 1 0 Putative GTPase activating protein for Arf DUF1126 PF06565.12 CBZ26500.1 - 1.6e-61 204.7 0.0 5.6e-22 77.6 0.0 3.4 3 0 0 3 3 3 3 DUF1126 PH-like domain EF-hand_7 PF13499.6 CBZ26500.1 - 1.6e-05 25.3 0.2 0.00023 21.6 0.0 2.9 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_8 PF13833.6 CBZ26500.1 - 6.8e-05 22.6 0.3 0.1 12.4 0.1 2.9 3 0 0 3 3 3 2 EF-hand domain pair Mac-1 PF09028.10 CBZ26500.1 - 0.047 12.8 0.1 0.081 12.0 0.1 1.3 1 0 0 1 1 1 0 Mac 1 MTHFR PF02219.17 CBZ26501.1 - 2.3e-94 315.9 0.0 2.8e-94 315.7 0.0 1.0 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase Ribosomal_S8e PF01201.22 CBZ26502.1 - 2.4e-45 154.0 3.3 2.4e-45 154.0 3.3 1.5 1 1 1 2 2 2 1 Ribosomal protein S8e DUF3746 PF12562.8 CBZ26502.1 - 0.076 12.9 0.5 0.41 10.6 0.2 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF3746) CCDC-167 PF15188.6 CBZ26502.1 - 0.32 11.4 3.0 0.68 10.3 3.0 1.6 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 167 Ribosomal_L26 PF16906.5 CBZ26502.1 - 1.3 9.5 6.4 21 5.6 0.1 2.4 2 0 0 2 2 2 0 Ribosomal proteins L26 eukaryotic, L24P archaeal HU-CCDC81_euk_2 PF18289.1 CBZ26503.1 - 3e-08 33.7 0.0 7.7e-08 32.4 0.0 1.6 2 0 0 2 2 2 1 CCDC81 eukaryotic HU domain 2 MarR_2 PF12802.7 CBZ26503.1 - 0.026 14.4 0.0 7.9 6.4 0.0 2.9 2 0 0 2 2 2 0 MarR family DprA_WH PF17782.1 CBZ26503.1 - 0.26 11.4 2.0 10 6.3 0.0 3.9 4 0 0 4 4 4 0 DprA winged helix domain Cytochrom_B558a PF05038.13 CBZ26504.1 - 0.086 12.4 0.0 0.11 12.1 0.0 1.2 1 0 0 1 1 1 0 Cytochrome Cytochrome b558 alpha-subunit TB2_DP1_HVA22 PF03134.19 CBZ26504.1 - 0.11 12.4 1.5 0.17 11.8 1.5 1.4 1 0 0 1 1 1 0 TB2/DP1, HVA22 family Sec23_trunk PF04811.15 CBZ26505.1 - 2.6e-50 171.3 0.0 4.8e-50 170.4 0.0 1.4 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.15 CBZ26505.1 - 3.5e-23 81.4 0.0 1.9e-22 79.0 0.0 2.2 2 0 0 2 2 2 1 Sec23/Sec24 helical domain Sec23_BS PF08033.12 CBZ26505.1 - 3.8e-20 72.4 1.1 3.8e-20 72.4 1.1 2.4 2 0 0 2 2 2 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.15 CBZ26505.1 - 1.2e-11 44.4 0.9 2.9e-11 43.2 0.9 1.7 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.22 CBZ26505.1 - 4.7e-05 23.2 0.0 0.00014 21.7 0.0 1.8 1 0 0 1 1 1 1 Gelsolin repeat DUF1539 PF07560.11 CBZ26506.1 - 0.016 15.3 0.3 0.16 12.0 0.1 2.0 1 1 0 2 2 2 0 Domain of Unknown Function (DUF1539) DUF4231 PF14015.6 CBZ26506.1 - 0.13 12.7 0.2 0.53 10.8 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF4231) UFD1 PF03152.14 CBZ26509.1 - 3.7e-46 156.8 0.0 4.6e-46 156.4 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin fusion degradation protein UFD1 Integrase_H2C2 PF17921.1 CBZ26510.1 - 0.37 10.9 1.6 17 5.6 0.0 2.9 3 0 0 3 3 3 0 Integrase zinc binding domain PCI PF01399.27 CBZ26511.1 - 0.00065 20.2 0.0 0.0014 19.1 0.0 1.6 1 0 0 1 1 1 1 PCI domain MFS_1 PF07690.16 CBZ26513.1 - 0.014 14.3 5.0 0.018 14.0 5.0 1.2 1 0 0 1 1 1 0 Major Facilitator Superfamily Phage_holin_3_6 PF07332.11 CBZ26513.1 - 0.05 13.6 3.2 0.26 11.4 2.4 2.0 2 0 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III COX7a PF02238.15 CBZ26513.1 - 0.1 13.0 0.8 0.1 13.0 0.8 2.8 2 1 1 3 3 3 0 Cytochrome c oxidase subunit VII DUF202 PF02656.15 CBZ26513.1 - 0.15 12.5 0.9 0.33 11.4 0.1 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF202) SdpI PF13630.6 CBZ26513.1 - 0.36 11.0 7.5 0.17 12.1 4.9 1.8 1 1 1 2 2 2 0 SdpI/YhfL protein family DUF2070 PF09843.9 CBZ26513.1 - 1.5 7.0 5.4 1.7 6.8 5.4 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) WTF PF03303.13 CBZ26513.1 - 2.3 7.9 8.9 7.4 6.2 8.9 1.8 1 1 0 1 1 1 0 WTF protein ZapB PF06005.12 CBZ26514.1 - 3 8.3 7.4 2.6 8.6 0.1 2.4 2 0 0 2 2 2 0 Cell division protein ZapB Myb_DNA-bind_7 PF15963.5 CBZ26515.1 - 7e-25 86.7 0.6 1.3e-24 85.9 0.6 1.5 1 0 0 1 1 1 1 Myb DNA-binding like Myb_DNA-binding PF00249.31 CBZ26515.1 - 9.3e-06 25.7 0.0 1.8e-05 24.8 0.0 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 CBZ26515.1 - 0.13 12.5 0.0 0.3 11.4 0.0 1.6 1 0 0 1 1 1 0 Myb-like DNA-binding domain DUF3432 PF11914.8 CBZ26515.1 - 4.4 7.6 9.3 5 7.4 0.6 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3432) DLH PF01738.18 CBZ26516.1 - 3.6e-22 79.0 0.0 4.5e-22 78.7 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_1 PF00561.20 CBZ26516.1 - 0.018 14.7 0.0 0.029 14.0 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold BAAT_C PF08840.11 CBZ26516.1 - 0.029 14.3 0.0 0.044 13.7 0.0 1.2 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal DUF3530 PF12048.8 CBZ26516.1 - 0.087 12.2 0.0 0.11 11.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3530) PCMT PF01135.19 CBZ26517.1 - 1.3e-46 159.0 0.0 1.8e-46 158.5 0.0 1.1 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) DUF4491 PF14898.6 CBZ26517.1 - 0.00039 20.8 0.3 0.76 10.3 0.0 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF4491) Methyltransf_32 PF13679.6 CBZ26517.1 - 0.0012 18.9 0.0 0.0017 18.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CBZ26517.1 - 0.006 16.4 0.0 0.0083 15.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_24 PF13578.6 CBZ26517.1 - 0.0071 17.3 0.0 0.011 16.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CBZ26517.1 - 0.015 16.0 0.0 0.025 15.3 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain DUF938 PF06080.12 CBZ26517.1 - 0.12 12.1 0.0 0.18 11.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF938) RrnaAD PF00398.20 CBZ26517.1 - 0.12 11.4 0.0 0.19 10.8 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Methyltransf_23 PF13489.6 CBZ26517.1 - 0.13 12.0 0.0 0.18 11.7 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.12 CBZ26517.1 - 0.14 12.9 0.0 0.32 11.7 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain ACBP PF00887.19 CBZ26518.1 - 1.5e-14 54.0 0.1 2.9e-14 53.0 0.1 1.5 1 0 0 1 1 1 1 Acyl CoA binding protein DUF4913 PF16259.5 CBZ26518.1 - 0.03 14.4 0.1 0.084 12.9 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4913) MRI PF15325.6 CBZ26518.1 - 0.088 13.9 1.7 0.21 12.7 1.7 1.6 1 0 0 1 1 1 0 Modulator of retrovirus infection SRP-alpha_N PF04086.13 CBZ26518.1 - 0.24 11.3 0.7 0.4 10.6 0.7 1.3 1 1 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Flavoprotein PF02441.19 CBZ26519.1 - 0.03 14.1 0.7 0.044 13.5 0.5 1.4 1 1 0 1 1 1 0 Flavoprotein DUF5320 PF17253.2 CBZ26519.1 - 0.031 15.3 0.6 0.093 13.8 0.6 1.8 1 0 0 1 1 1 0 Family of unknown function (DUF5320) HEAT_EZ PF13513.6 CBZ26519.1 - 0.056 14.0 2.1 0.14 12.7 2.1 1.7 1 0 0 1 1 1 0 HEAT-like repeat SRI PF08236.11 CBZ26519.1 - 0.097 12.9 1.5 0.11 12.7 0.1 1.7 2 0 0 2 2 2 0 SRI (Set2 Rpb1 interacting) domain FXMRP1_C_core PF12235.8 CBZ26519.1 - 2.9 8.5 6.3 1.3 9.7 0.1 2.6 2 1 0 2 2 2 0 Fragile X-related 1 protein core C terminal PA26 PF04636.13 CBZ26519.1 - 3.8 6.3 4.9 5.2 5.9 4.9 1.1 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) DUF4551 PF15087.6 CBZ26519.1 - 4.5 6.0 6.2 6 5.6 6.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) zf-PARP PF00645.18 CBZ26520.1 - 0.067 14.1 0.0 0.11 13.4 0.0 1.3 1 0 0 1 1 1 0 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region NYD-SP28_assoc PF14775.6 CBZ26521.1 - 4.6e-21 74.7 3.9 4.6e-21 74.7 3.9 4.5 4 2 2 6 6 6 1 Sperm tail C-terminal domain NYD-SP28 PF14772.6 CBZ26521.1 - 2.1e-18 66.2 4.4 2.1e-18 66.2 4.4 5.3 5 1 2 7 7 7 2 Sperm tail Ovate PF04844.13 CBZ26521.1 - 0.14 12.2 0.8 20 5.2 0.0 3.5 3 1 1 4 4 4 0 Transcriptional repressor, ovate FliD_C PF07195.12 CBZ26521.1 - 0.15 11.4 20.7 0.06 12.8 3.5 3.7 3 0 0 3 3 3 0 Flagellar hook-associated protein 2 C-terminus DUF948 PF06103.11 CBZ26521.1 - 1.1 9.5 6.3 15 5.9 0.4 3.5 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) Mito_carr PF00153.27 CBZ26523.1 - 1e-33 115.1 3.9 9.7e-13 47.9 0.0 3.2 2 1 1 3 3 3 3 Mitochondrial carrier protein CcmD PF04995.14 CBZ26524.1 - 0.34 11.0 0.1 0.34 11.0 0.1 4.2 4 0 0 4 4 4 0 Heme exporter protein D (CcmD) KASH PF10541.9 CBZ26524.1 - 0.49 10.7 0.1 0.49 10.7 0.1 4.4 5 0 0 5 5 5 0 Nuclear envelope localisation domain DUF3619 PF12279.8 CBZ26524.1 - 1.6 9.1 5.9 18 5.7 0.3 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF3619) SAS-6_N PF16531.5 CBZ26526.1 - 5.5e-23 81.4 0.2 8e-23 80.8 0.2 1.3 1 0 0 1 1 1 1 Centriolar protein SAS N-terminal Pneumo_matrix PF03393.16 CBZ26526.1 - 0.014 14.7 0.0 0.028 13.7 0.0 1.5 1 1 1 2 2 2 0 Pneumovirus matrix protein CSD PF00313.22 CBZ26526.1 - 0.12 12.3 0.0 0.29 11.0 0.0 1.6 2 0 0 2 2 2 0 'Cold-shock' DNA-binding domain Metalloenzyme PF01676.18 CBZ26527.1 - 5.4e-80 268.3 0.0 6.2e-80 268.1 0.0 1.0 1 0 0 1 1 1 1 Metalloenzyme superfamily iPGM_N PF06415.13 CBZ26527.1 - 2.9e-60 203.4 0.0 4e-60 203.0 0.0 1.2 1 0 0 1 1 1 1 BPG-independent PGAM N-terminus (iPGM_N) Phosphodiest PF01663.22 CBZ26527.1 - 0.00057 19.6 0.0 0.0017 18.1 0.0 1.7 2 0 0 2 2 2 1 Type I phosphodiesterase / nucleotide pyrophosphatase PglZ PF08665.12 CBZ26527.1 - 0.011 15.8 0.0 0.02 15.0 0.0 1.4 1 0 0 1 1 1 0 PglZ domain Alk_phosphatase PF00245.20 CBZ26527.1 - 0.046 12.7 0.1 0.11 11.4 0.1 1.6 2 0 0 2 2 2 0 Alkaline phosphatase DUF3659 PF12396.8 CBZ26527.1 - 2.9 7.9 5.3 2.8 7.9 0.2 3.1 2 1 0 2 2 2 0 Protein of unknown function (DUF3659) FtsJ PF01728.19 CBZ26528.1 - 1.4e-27 96.9 0.0 2.6e-27 96.1 0.0 1.4 2 0 0 2 2 2 1 FtsJ-like methyltransferase Cyt-b5 PF00173.28 CBZ26529.1 - 7.3e-12 45.3 0.0 9.4e-12 44.9 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Apolipoprotein PF01442.18 CBZ26530.1 - 0.03 14.2 14.3 0.041 13.8 14.3 1.2 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain DUF4407 PF14362.6 CBZ26530.1 - 0.044 13.2 10.5 0.055 12.8 10.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) EOS1 PF12326.8 CBZ26530.1 - 0.046 13.7 0.6 0.066 13.1 0.6 1.2 1 0 0 1 1 1 0 N-glycosylation protein Val_tRNA-synt_C PF10458.9 CBZ26530.1 - 0.062 13.6 0.1 0.062 13.6 0.1 3.8 3 1 0 3 3 3 0 Valyl tRNA synthetase tRNA binding arm bZIP_2 PF07716.15 CBZ26530.1 - 0.065 13.3 2.5 0.065 13.3 2.5 3.9 3 1 1 4 4 4 0 Basic region leucine zipper DUF4239 PF14023.6 CBZ26530.1 - 0.12 12.1 3.7 0.15 11.8 3.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4239) DASH_Dad4 PF08650.10 CBZ26530.1 - 0.12 12.3 7.3 0.16 12.0 1.5 2.9 1 1 2 3 3 3 0 DASH complex subunit Dad4 UPF0242 PF06785.11 CBZ26530.1 - 0.61 10.2 15.8 0.94 9.5 15.8 1.3 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus ABC_tran_CTD PF16326.5 CBZ26530.1 - 0.73 10.1 21.2 1.2e+02 3.0 10.4 4.0 1 1 2 3 3 3 0 ABC transporter C-terminal domain BBP1_C PF15272.6 CBZ26530.1 - 0.74 9.6 9.9 4.6 7.0 0.1 2.1 1 1 1 2 2 2 0 Spindle pole body component BBP1, C-terminal GAS PF13851.6 CBZ26530.1 - 0.92 8.8 17.0 2.2 7.6 17.0 1.5 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding Uso1_p115_C PF04871.13 CBZ26530.1 - 1.9 8.9 13.1 8.9 6.7 12.9 2.0 1 1 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region Exonuc_VII_L PF02601.15 CBZ26530.1 - 1.9 8.0 8.9 2.2 7.7 8.9 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit GrpE PF01025.19 CBZ26530.1 - 2.2 7.9 14.3 0.27 10.9 0.3 2.3 1 1 0 2 2 2 0 GrpE ACCA PF03255.14 CBZ26530.1 - 3.2 7.6 9.9 2.4 8.1 1.2 2.4 1 1 1 2 2 2 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit DUF812 PF05667.11 CBZ26530.1 - 3.3 6.5 16.8 5.8 5.7 16.8 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF812) DASH_Hsk3 PF08227.11 CBZ26530.1 - 3.8 7.9 9.7 13 6.3 0.2 3.5 3 0 0 3 3 3 0 DASH complex subunit Hsk3 like Spc7 PF08317.11 CBZ26530.1 - 5.3 5.8 18.0 0.17 10.7 1.5 2.0 1 1 1 2 2 2 0 Spc7 kinetochore protein FAM76 PF16046.5 CBZ26530.1 - 5.6 6.2 8.3 8.3 5.7 8.3 1.5 1 1 0 1 1 1 0 FAM76 protein Solute_trans_a PF03619.16 CBZ26531.1 - 1.3e-77 260.9 19.4 2.2e-77 260.2 19.4 1.3 1 0 0 1 1 1 1 Organic solute transporter Ostalpha DUF4337 PF14235.6 CBZ26531.1 - 1.2 9.2 2.5 40 4.3 0.0 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4337) AAA_22 PF13401.6 CBZ26532.1 - 5.5e-05 23.5 0.0 0.00015 22.0 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 CBZ26532.1 - 0.00012 22.5 0.4 0.00073 20.0 0.1 2.4 2 1 0 2 2 2 1 AAA ATPase domain NACHT PF05729.12 CBZ26532.1 - 0.018 15.0 0.0 0.032 14.2 0.0 1.5 1 0 0 1 1 1 0 NACHT domain AAA_28 PF13521.6 CBZ26532.1 - 0.07 13.4 0.0 0.17 12.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain DNA_pol3_delta2 PF13177.6 CBZ26533.1 - 1.6e-14 54.0 0.0 2.5e-14 53.4 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA PF00004.29 CBZ26533.1 - 2.5e-07 31.2 0.0 8.7e-07 29.4 0.0 1.9 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 CBZ26533.1 - 0.00022 21.2 0.0 0.00045 20.2 0.0 1.6 1 1 0 1 1 1 1 Rad17 P-loop domain AAA_24 PF13479.6 CBZ26533.1 - 0.00034 20.4 0.0 0.00075 19.3 0.0 1.5 2 0 0 2 2 2 1 AAA domain Rep_fac_C PF08542.11 CBZ26533.1 - 0.00035 20.9 0.1 0.00071 19.9 0.1 1.5 1 0 0 1 1 1 1 Replication factor C C-terminal domain AAA_5 PF07728.14 CBZ26533.1 - 0.0025 17.8 0.1 0.027 14.5 0.1 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 CBZ26533.1 - 0.0038 16.6 0.0 0.11 11.8 0.0 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI RuvB_N PF05496.12 CBZ26533.1 - 0.0045 16.8 0.0 0.18 11.5 0.0 2.8 3 0 0 3 3 3 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 CBZ26533.1 - 0.0054 17.1 0.0 0.14 12.5 0.0 2.5 2 1 0 2 2 2 1 AAA ATPase domain Sigma54_activ_2 PF14532.6 CBZ26533.1 - 0.022 14.9 0.0 0.99 9.5 0.0 2.3 2 0 0 2 2 2 0 Sigma-54 interaction domain Sigma54_activat PF00158.26 CBZ26533.1 - 0.039 13.7 0.0 3 7.5 0.0 2.7 3 0 0 3 3 3 0 Sigma-54 interaction domain AAA_22 PF13401.6 CBZ26533.1 - 0.057 13.7 0.1 0.4 11.0 0.0 2.3 2 1 0 2 2 2 0 AAA domain Peptidase_S9_N PF02897.15 CBZ26537.1 - 3.7e-94 315.9 4.1 4.9e-94 315.5 4.1 1.1 1 0 0 1 1 1 1 Prolyl oligopeptidase, N-terminal beta-propeller domain Peptidase_S9 PF00326.21 CBZ26537.1 - 3.9e-65 219.3 0.0 7.8e-65 218.3 0.0 1.5 1 0 0 1 1 1 1 Prolyl oligopeptidase family Esterase PF00756.20 CBZ26537.1 - 0.00025 20.8 0.0 0.00047 19.9 0.0 1.4 1 0 0 1 1 1 1 Putative esterase DUF4019 PF13211.6 CBZ26537.1 - 0.029 14.7 0.3 10 6.6 0.2 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF4019) Hydrolase_4 PF12146.8 CBZ26537.1 - 0.055 12.7 0.0 0.13 11.5 0.0 1.5 1 0 0 1 1 1 0 Serine aminopeptidase, S33 AXE1 PF05448.12 CBZ26537.1 - 0.066 11.9 0.0 0.13 10.9 0.0 1.4 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) Abhydrolase_3 PF07859.13 CBZ26537.1 - 0.066 13.1 0.2 0.14 12.0 0.2 1.6 1 1 0 1 1 1 0 alpha/beta hydrolase fold Nodulin PF02451.15 CBZ26537.1 - 0.069 12.6 0.0 0.12 11.8 0.0 1.3 1 0 0 1 1 1 0 Nodulin Abhydrolase_1 PF00561.20 CBZ26537.1 - 0.09 12.4 0.1 0.76 9.4 0.1 2.2 1 1 1 2 2 2 0 alpha/beta hydrolase fold OSCP PF00213.18 CBZ26538.1 - 8.5e-07 29.2 0.3 3.7e-06 27.2 0.3 2.0 1 1 0 1 1 1 1 ATP synthase delta (OSCP) subunit Adaptin_N PF01602.20 CBZ26539.1 - 4.5e-102 342.3 4.2 5.9e-102 341.9 4.2 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 CBZ26539.1 - 1.7e-48 164.8 2.2 2.1e-47 161.2 0.0 2.9 3 1 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 CBZ26539.1 - 5.4e-11 42.7 2.6 7.1e-07 29.5 0.0 4.6 4 1 0 4 4 4 2 HEAT repeats HEAT PF02985.22 CBZ26539.1 - 1e-07 31.6 2.3 0.04 14.2 0.0 5.0 4 0 0 4 4 4 1 HEAT repeat RTP1_C1 PF10363.9 CBZ26539.1 - 0.00018 21.7 0.4 0.26 11.5 0.0 3.6 3 1 0 3 3 3 2 Required for nuclear transport of RNA pol II C-terminus 1 RIX1 PF08167.12 CBZ26539.1 - 0.00031 20.5 1.4 0.14 11.9 0.2 3.6 3 1 1 4 4 4 1 rRNA processing/ribosome biogenesis VHS PF00790.19 CBZ26539.1 - 0.012 15.5 0.1 0.033 14.0 0.1 1.8 1 0 0 1 1 1 0 VHS domain PD-C2-AF1 PF09310.10 CBZ26539.1 - 0.076 12.4 0.1 0.15 11.5 0.1 1.4 1 0 0 1 1 1 0 POU domain, class 2, associating factor 1 CAP18_C PF12153.8 CBZ26539.1 - 0.16 11.9 0.5 0.39 10.6 0.5 1.7 1 0 0 1 1 1 0 LPS binding domain of CAP18 (C terminal) NIF PF03031.18 CBZ26540.1 - 5.5e-31 107.5 0.0 7.5e-31 107.0 0.0 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase AFG1_ATPase PF03969.16 CBZ26542.1 - 1.2e-55 188.9 4.4 4.2e-55 187.1 0.1 2.3 3 0 0 3 3 3 2 AFG1-like ATPase AAA_16 PF13191.6 CBZ26542.1 - 9.8e-05 22.8 0.7 0.0008 19.8 0.1 2.6 2 1 1 3 3 3 1 AAA ATPase domain AAA_22 PF13401.6 CBZ26542.1 - 0.05 13.9 0.0 0.47 10.7 0.0 2.5 2 1 0 2 2 2 0 AAA domain AAA_19 PF13245.6 CBZ26542.1 - 0.15 12.4 0.1 2.9 8.2 0.0 2.6 2 1 0 2 2 2 0 AAA domain E3_UFM1_ligase PF09743.9 CBZ26543.1 - 4.6e-70 236.3 0.0 7.9e-70 235.6 0.0 1.4 1 0 0 1 1 1 1 E3 UFM1-protein ligase 1 VASP_tetra PF08776.11 CBZ26543.1 - 7.6 6.2 5.6 37 4.0 0.1 3.3 4 0 0 4 4 4 0 VASP tetramerisation domain 4HBT PF03061.22 CBZ26544.1 - 3.5e-06 27.3 0.0 6.2e-06 26.5 0.0 1.4 1 0 0 1 1 1 1 Thioesterase superfamily DUF4442 PF14539.6 CBZ26544.1 - 0.0014 18.8 0.0 0.0017 18.5 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4442) 4HBT_3 PF13622.6 CBZ26544.1 - 0.068 13.4 0.9 0.077 13.2 0.0 1.4 2 0 0 2 2 2 0 Thioesterase-like superfamily SET PF00856.28 CBZ26545.1 - 9.6e-06 26.1 0.0 0.00044 20.7 0.0 2.3 1 1 0 1 1 1 1 SET domain Aa_trans PF01490.18 CBZ26546.1 - 3.8e-42 144.4 32.5 4.5e-42 144.2 32.5 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein MuF_C PF18819.1 CBZ26546.1 - 0.15 12.1 0.0 0.26 11.3 0.0 1.3 1 0 0 1 1 1 0 Phage MuF-C-terminal domain TMEM65 PF10507.9 CBZ26547.1 - 1.4e-36 124.7 3.0 3.2e-36 123.6 3.0 1.6 1 0 0 1 1 1 1 Transmembrane protein 65 EF-hand_1 PF00036.32 CBZ26547.1 - 2.4e-07 29.8 0.2 0.0038 16.7 0.0 3.3 4 0 0 4 4 4 2 EF hand EF-hand_6 PF13405.6 CBZ26547.1 - 3.8e-05 23.3 0.0 0.027 14.4 0.0 3.1 3 0 0 3 3 3 2 EF-hand domain EF-hand_14 PF17959.1 CBZ26547.1 - 0.00073 19.8 0.2 0.0028 18.0 0.0 2.0 2 0 0 2 2 2 1 EF-hand domain EF-hand_7 PF13499.6 CBZ26547.1 - 0.0014 19.0 2.1 0.26 11.8 0.1 2.7 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_5 PF13202.6 CBZ26547.1 - 0.021 14.3 0.7 0.73 9.4 0.0 3.2 3 0 0 3 3 3 0 EF hand RNA_lig_T4_1 PF09511.10 CBZ26549.1 - 1.1e-29 103.9 0.0 2.4e-29 102.8 0.0 1.7 1 0 0 1 1 1 1 RNA ligase AAA_33 PF13671.6 CBZ26549.1 - 1.1e-11 45.0 0.2 3.2e-11 43.6 0.2 1.8 1 0 0 1 1 1 1 AAA domain 6PF2K PF01591.18 CBZ26549.1 - 2.1e-07 30.5 0.0 3.7e-07 29.7 0.0 1.3 1 0 0 1 1 1 1 6-phosphofructo-2-kinase AAA_18 PF13238.6 CBZ26549.1 - 1.1e-06 29.2 0.0 2.4e-06 28.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain NACHT PF05729.12 CBZ26549.1 - 3.2e-06 27.2 1.0 8.9e-06 25.7 0.8 2.0 1 1 0 1 1 1 1 NACHT domain APS_kinase PF01583.20 CBZ26549.1 - 5.9e-05 23.0 0.2 0.00025 21.0 0.0 2.3 2 1 0 2 2 1 1 Adenylylsulphate kinase ABC_tran PF00005.27 CBZ26549.1 - 0.00075 20.0 0.0 0.0023 18.5 0.0 1.9 1 0 0 1 1 1 1 ABC transporter KTI12 PF08433.10 CBZ26549.1 - 0.00099 18.6 0.0 0.0018 17.8 0.0 1.3 1 0 0 1 1 1 1 Chromatin associated protein KTI12 CPT PF07931.12 CBZ26549.1 - 0.0023 17.8 0.4 0.13 12.1 0.1 2.7 2 0 0 2 2 2 1 Chloramphenicol phosphotransferase-like protein AAA_16 PF13191.6 CBZ26549.1 - 0.0069 16.8 1.9 0.021 15.2 0.8 2.5 2 1 0 2 2 2 1 AAA ATPase domain AAA_17 PF13207.6 CBZ26549.1 - 0.011 16.1 0.0 0.024 15.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 CBZ26549.1 - 0.017 14.4 0.0 0.04 13.2 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin AAA_25 PF13481.6 CBZ26549.1 - 0.025 14.2 2.9 0.087 12.4 0.3 2.7 1 1 0 2 2 2 0 AAA domain AAA_28 PF13521.6 CBZ26549.1 - 0.036 14.3 0.0 0.14 12.4 0.0 2.1 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 CBZ26549.1 - 0.038 14.3 0.0 0.14 12.5 0.0 2.1 1 1 0 1 1 1 0 AAA domain AAA_5 PF07728.14 CBZ26549.1 - 0.041 13.9 0.0 0.097 12.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.17 CBZ26549.1 - 0.075 12.8 0.4 0.15 11.8 0.0 1.6 2 0 0 2 2 1 0 IstB-like ATP binding protein Mg_chelatase PF01078.21 CBZ26549.1 - 0.12 11.8 0.0 0.34 10.3 0.0 1.8 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI LAM_C PF12544.8 CBZ26549.1 - 0.12 12.6 0.0 0.24 11.6 0.0 1.4 1 0 0 1 1 1 0 Lysine-2,3-aminomutase MMR_HSR1 PF01926.23 CBZ26549.1 - 0.16 12.1 0.0 0.42 10.7 0.0 1.7 1 0 0 1 1 1 0 50S ribosome-binding GTPase TIP49 PF06068.13 CBZ26549.1 - 0.16 11.1 0.0 0.27 10.4 0.0 1.3 1 0 0 1 1 1 0 TIP49 P-loop domain EVE PF01878.18 CBZ26551.1 - 1.2e-52 177.7 0.2 1.4e-52 177.6 0.2 1.0 1 0 0 1 1 1 1 EVE domain Bromodomain PF00439.25 CBZ26552.1 - 1.6e-17 63.3 0.1 2.8e-17 62.5 0.1 1.4 1 0 0 1 1 1 1 Bromodomain Mqo PF06039.15 CBZ26552.1 - 0.11 11.0 0.2 0.16 10.5 0.2 1.1 1 0 0 1 1 1 0 Malate:quinone oxidoreductase (Mqo) NolB PF17398.2 CBZ26552.1 - 0.12 12.8 0.9 0.9 9.9 0.0 2.2 1 1 1 2 2 2 0 Nodulation protein NolB Nucleoporin_N PF08801.11 CBZ26553.1 - 8.9e-58 196.1 0.0 1.5e-57 195.3 0.0 1.3 1 0 0 1 1 1 1 Nup133 N terminal like LRR_8 PF13855.6 CBZ26554.1 - 0.00083 19.1 0.4 0.00083 19.1 0.4 2.5 3 1 0 3 3 3 1 Leucine rich repeat LRR_4 PF12799.7 CBZ26554.1 - 0.0011 19.3 1.4 0.02 15.3 0.1 3.1 2 1 1 3 3 3 2 Leucine Rich repeats (2 copies) Cpn60_TCP1 PF00118.24 CBZ26555.1 - 6.7e-154 513.1 9.9 7.7e-154 513.0 9.9 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family DUF374 PF04028.13 CBZ26555.1 - 0.021 14.4 0.2 0.13 11.8 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF374) eIF3_subunit PF08597.10 CBZ26555.1 - 0.15 11.9 0.0 0.27 11.1 0.0 1.3 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit Ribosomal_L1 PF00687.21 CBZ26556.1 - 1.9e-20 73.5 0.0 2.6e-20 73.0 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family zf-C2H2_6 PF13912.6 CBZ26557.1 - 2.6e-07 30.5 11.4 2.8e-06 27.2 1.6 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf_C2H2_ZHX PF18387.1 CBZ26557.1 - 0.00046 19.8 0.9 0.027 14.1 0.1 2.3 2 0 0 2 2 2 1 Zinc-fingers and homeoboxes C2H2 finger domain zf-C2H2_4 PF13894.6 CBZ26557.1 - 0.003 18.3 11.2 0.029 15.2 2.3 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.26 CBZ26557.1 - 0.013 15.9 9.5 0.13 12.8 2.7 2.7 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 CBZ26557.1 - 0.083 13.4 8.1 3.2 8.3 0.2 3.7 3 0 0 3 3 3 0 Zinc-finger double domain zf-Di19 PF05605.12 CBZ26557.1 - 0.093 13.0 1.5 14 6.0 0.1 2.4 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding Vps39_2 PF10367.9 CBZ26557.1 - 0.098 13.1 0.4 19 5.7 0.1 2.3 2 0 0 2 2 2 0 Vacuolar sorting protein 39 domain 2 zf-C2H2_2 PF12756.7 CBZ26557.1 - 0.14 12.5 0.7 7.7 6.9 0.1 2.2 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-met PF12874.7 CBZ26557.1 - 0.2 12.1 4.7 1.6 9.2 0.4 2.5 2 0 0 2 2 2 0 Zinc-finger of C2H2 type DUF629 PF04780.12 CBZ26557.1 - 0.72 8.3 2.4 2.7 6.4 0.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF629) zf-C2H2_jaz PF12171.8 CBZ26557.1 - 1.5 9.2 3.8 18 5.8 0.2 2.3 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding HEPN_SAV2148 PF18725.1 CBZ26558.1 - 0.038 13.4 0.0 0.06 12.8 0.0 1.3 1 0 0 1 1 1 0 SAV2148-like HEPN Thioredoxin PF00085.20 CBZ26559.1 - 3.6e-61 203.6 0.2 1.5e-31 108.5 0.1 3.4 3 0 0 3 3 3 2 Thioredoxin Thioredoxin_6 PF13848.6 CBZ26559.1 - 7.5e-24 84.6 0.1 3.4e-14 53.2 0.0 3.8 2 2 1 3 3 3 3 Thioredoxin-like domain Thioredoxin_2 PF13098.6 CBZ26559.1 - 6.8e-13 49.0 1.1 2.8e-05 24.5 0.1 3.4 2 2 0 2 2 2 2 Thioredoxin-like domain AhpC-TSA PF00578.21 CBZ26559.1 - 3.2e-10 40.0 0.4 0.00027 20.8 0.0 3.0 3 1 0 3 3 3 2 AhpC/TSA family Thioredoxin_7 PF13899.6 CBZ26559.1 - 2.3e-09 37.3 0.0 0.00087 19.4 0.0 2.7 2 0 0 2 2 2 2 Thioredoxin-like Thioredoxin_8 PF13905.6 CBZ26559.1 - 2.8e-09 37.2 1.1 0.082 13.2 0.0 4.4 4 2 2 6 6 6 3 Thioredoxin-like OST3_OST6 PF04756.13 CBZ26559.1 - 2.1e-07 30.6 0.0 0.00023 20.6 0.0 2.5 2 0 0 2 2 2 2 OST3 / OST6 family, transporter family TraF PF13728.6 CBZ26559.1 - 0.00012 22.0 0.0 0.066 13.0 0.0 3.2 2 1 0 2 2 2 1 F plasmid transfer operon protein Thioredoxin_9 PF14595.6 CBZ26559.1 - 0.00017 21.4 0.0 0.19 11.5 0.0 2.6 2 0 0 2 2 2 2 Thioredoxin Redoxin PF08534.10 CBZ26559.1 - 0.00087 19.0 0.6 0.11 12.2 0.0 3.0 3 0 0 3 3 3 1 Redoxin Thioredoxin_3 PF13192.6 CBZ26559.1 - 0.0039 17.2 0.0 3.4 7.8 0.0 2.8 2 0 0 2 2 2 2 Thioredoxin domain HyaE PF07449.11 CBZ26559.1 - 0.0079 16.1 0.0 0.13 12.3 0.0 2.5 2 0 0 2 2 2 1 Hydrogenase-1 expression protein HyaE Calsequestrin PF01216.17 CBZ26559.1 - 0.013 14.5 0.4 0.027 13.5 0.1 1.6 2 0 0 2 2 2 0 Calsequestrin FA_desaturase PF00487.24 CBZ26560.1 - 6.8e-31 108.0 11.5 1.1e-30 107.3 11.5 1.3 1 0 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.28 CBZ26560.1 - 1.3e-10 41.2 0.0 2.7e-10 40.2 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain DUF2924 PF11149.8 CBZ26561.1 - 0.041 14.3 0.6 0.041 14.3 0.6 2.9 2 1 2 4 4 4 0 Protein of unknown function (DUF2924) DUF2208 PF09973.9 CBZ26561.1 - 0.15 11.7 1.0 0.85 9.2 0.1 2.2 2 0 0 2 2 2 0 Predicted membrane protein (DUF2208) Methyltransf_23 PF13489.6 CBZ26562.1 - 0.026 14.4 0.0 0.036 13.9 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain eIF-3c_N PF05470.12 CBZ26563.1 - 1.7e-20 72.9 1.0 1.2e-15 56.8 0.0 2.7 2 1 0 2 2 2 2 Eukaryotic translation initiation factor 3 subunit 8 N-terminus PCI PF01399.27 CBZ26563.1 - 0.049 14.1 0.1 0.28 11.7 0.0 2.3 2 0 0 2 2 2 0 PCI domain RRM_1 PF00076.22 CBZ26564.1 - 0.00018 21.3 0.0 0.00037 20.3 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 CBZ26564.1 - 0.018 14.6 0.0 0.026 14.1 0.0 1.3 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.8 CBZ26564.1 - 0.02 14.9 0.0 0.035 14.2 0.0 1.4 1 0 0 1 1 1 0 Limkain b1 MOZ_SAS PF01853.18 CBZ26565.1 - 1.6e-46 158.2 0.0 2.1e-46 157.9 0.0 1.1 1 0 0 1 1 1 1 MOZ/SAS family zf-MYST PF17772.1 CBZ26565.1 - 0.0057 16.2 1.4 0.01 15.5 1.4 1.4 1 0 0 1 1 1 1 MYST family zinc finger domain Acetyltransf_7 PF13508.7 CBZ26565.1 - 0.016 15.7 0.0 0.032 14.6 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain zf-C4_ClpX PF06689.13 CBZ26565.1 - 0.017 15.0 0.2 0.035 14.0 0.2 1.5 1 0 0 1 1 1 0 ClpX C4-type zinc finger Peptidase_C23 PF05379.11 CBZ26565.1 - 0.077 13.1 0.0 0.16 12.1 0.0 1.5 1 0 0 1 1 1 0 Carlavirus endopeptidase FR47 PF08445.10 CBZ26565.1 - 0.14 12.1 0.0 0.27 11.2 0.0 1.5 1 0 0 1 1 1 0 FR47-like protein PSP1 PF04468.12 CBZ26567.1 - 1.5e-27 95.7 0.2 2.7e-27 94.9 0.2 1.4 1 0 0 1 1 1 1 PSP1 C-terminal conserved region RNA_pol_Rpb2_6 PF00562.28 CBZ26568.1 - 1.5e-116 389.7 0.0 2.7e-116 388.9 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 CBZ26568.1 - 4.1e-46 157.1 1.0 5.9e-46 156.5 1.0 1.2 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_7 PF04560.20 CBZ26568.1 - 2.1e-32 111.4 0.2 7e-32 109.7 0.2 2.0 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_2 PF04561.14 CBZ26568.1 - 2.4e-20 73.0 0.1 4.9e-20 72.0 0.1 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_4 PF04566.13 CBZ26568.1 - 3.2e-19 69.0 1.7 3.2e-19 69.0 1.7 2.0 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_3 PF04565.16 CBZ26568.1 - 3.5e-19 68.8 0.0 7.1e-19 67.8 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_5 PF04567.17 CBZ26568.1 - 1e-08 35.6 0.2 3.4e-08 33.9 0.2 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 Chlorophyllase PF07224.11 CBZ26568.1 - 0.1 11.6 0.0 0.18 10.8 0.0 1.3 1 0 0 1 1 1 0 Chlorophyllase WD40 PF00400.32 CBZ26569.1 - 5.7e-17 61.8 8.3 4.4e-05 24.2 0.3 5.4 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBZ26569.1 - 1.2e-05 25.5 0.0 0.38 11.1 0.0 3.0 2 1 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 CBZ26569.1 - 0.011 14.5 3.1 0.27 9.8 0.2 2.9 2 1 1 3 3 3 0 Nucleoporin Nup120/160 Hira PF07569.11 CBZ26569.1 - 0.14 11.9 2.1 13 5.5 0.0 3.0 3 1 0 3 3 3 0 TUP1-like enhancer of split DOT1 PF08123.13 CBZ26570.1 - 7.4e-20 71.4 0.0 9.7e-20 71.0 0.0 1.1 1 0 0 1 1 1 1 Histone methylation protein DOT1 Methyltransf_25 PF13649.6 CBZ26570.1 - 5.9e-05 23.7 0.0 0.0001 22.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CBZ26570.1 - 6.8e-05 22.7 0.0 9.7e-05 22.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CBZ26570.1 - 0.00014 22.5 0.0 0.00025 21.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 CBZ26570.1 - 0.0024 17.7 0.0 0.003 17.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 CBZ26570.1 - 0.014 14.7 0.0 0.019 14.3 0.0 1.1 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_32 PF13679.6 CBZ26570.1 - 0.034 14.1 0.0 0.062 13.3 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.12 CBZ26570.1 - 0.042 14.6 0.0 0.071 13.9 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain AdoMet_MTase PF07757.13 CBZ26570.1 - 0.12 12.7 0.0 0.18 12.1 0.0 1.3 1 0 0 1 1 1 0 Predicted AdoMet-dependent methyltransferase PHO4 PF01384.20 CBZ26571.1 - 1.4e-101 339.9 19.0 1.8e-101 339.6 19.0 1.1 1 0 0 1 1 1 1 Phosphate transporter family ASF1_hist_chap PF04729.13 CBZ26573.1 - 1.4e-44 151.8 0.0 1.7e-44 151.5 0.0 1.0 1 0 0 1 1 1 1 ASF1 like histone chaperone TetR_C_30 PF17939.1 CBZ26573.1 - 0.041 14.1 0.1 3.8 7.8 0.0 2.1 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain BRCA-2_OB1 PF09103.10 CBZ26574.1 - 3.1e-24 85.3 0.0 5.1e-24 84.6 0.0 1.4 1 0 0 1 1 1 1 BRCA2, oligonucleotide/oligosaccharide-binding, domain 1 BRCA2 PF00634.18 CBZ26574.1 - 1.4e-08 34.3 0.0 9.7e-05 22.0 0.0 2.6 2 0 0 2 2 2 2 BRCA2 repeat zf-RanBP PF00641.18 CBZ26574.1 - 0.032 13.6 2.6 0.081 12.3 2.6 1.7 1 0 0 1 1 1 0 Zn-finger in Ran binding protein and others MRG PF05712.13 CBZ26575.1 - 0.0078 15.5 0.0 0.0095 15.3 0.0 1.1 1 0 0 1 1 1 1 MRG Ion_trans_2 PF07885.16 CBZ26577.1 - 1.5e-12 47.3 6.1 1.5e-12 47.3 6.1 2.5 3 0 0 3 3 3 1 Ion channel BK_channel_a PF03493.18 CBZ26577.1 - 2.1e-12 47.1 0.0 7.1e-11 42.2 0.0 2.6 2 0 0 2 2 2 1 Calcium-activated BK potassium channel alpha subunit PGK PF00162.19 CBZ26578.1 - 1.6e-154 514.4 0.0 1.9e-154 514.2 0.0 1.0 1 0 0 1 1 1 1 Phosphoglycerate kinase PGK PF00162.19 CBZ26579.1 - 1e-154 515.1 0.0 1.1e-154 514.9 0.0 1.0 1 0 0 1 1 1 1 Phosphoglycerate kinase AAA_16 PF13191.6 CBZ26580.1 - 1.8e-06 28.4 0.6 3.9e-05 24.1 0.1 3.0 2 1 0 2 2 2 1 AAA ATPase domain NB-ARC PF00931.22 CBZ26580.1 - 2.6e-06 26.8 0.0 0.015 14.5 0.0 2.2 1 1 1 2 2 2 2 NB-ARC domain AAA_25 PF13481.6 CBZ26580.1 - 0.021 14.4 0.0 0.044 13.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 CBZ26580.1 - 0.021 14.7 0.0 0.18 11.7 0.0 2.2 1 1 0 1 1 1 0 NACHT domain AAA_7 PF12775.7 CBZ26580.1 - 0.032 13.7 0.0 0.061 12.8 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA PF00004.29 CBZ26580.1 - 0.043 14.3 0.0 0.077 13.4 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 CBZ26580.1 - 0.11 12.9 0.0 0.3 11.5 0.0 1.8 2 0 0 2 2 2 0 RNA helicase AAA_24 PF13479.6 CBZ26580.1 - 0.14 11.9 0.0 0.23 11.2 0.0 1.2 1 0 0 1 1 1 0 AAA domain TetR_C_11 PF16859.5 CBZ26580.1 - 3.4 8.0 8.5 1.7 9.0 1.8 3.2 3 0 0 3 3 3 0 Tetracyclin repressor-like, C-terminal domain MORN PF02493.20 CBZ26581.1 - 1.5e-11 43.5 12.9 1.5e-06 27.7 0.0 7.3 7 1 0 7 7 7 3 MORN repeat DUF1736 PF08409.11 CBZ26583.1 - 4.6e-17 61.8 1.6 1.3e-16 60.3 0.5 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF1736) Ada3 PF10198.9 CBZ26584.1 - 0.00062 19.9 4.6 0.0018 18.4 4.6 1.8 1 0 0 1 1 1 1 Histone acetyltransferases subunit 3 Fez1 PF06818.15 CBZ26584.1 - 0.016 15.7 15.1 0.038 14.5 10.8 2.4 2 0 0 2 2 2 0 Fez1 AAA_13 PF13166.6 CBZ26584.1 - 0.043 12.5 7.1 0.068 11.8 7.1 1.2 1 0 0 1 1 1 0 AAA domain TMF_TATA_bd PF12325.8 CBZ26584.1 - 0.086 13.1 21.0 0.042 14.1 8.0 3.4 2 1 1 3 3 3 0 TATA element modulatory factor 1 TATA binding RILP PF11461.8 CBZ26584.1 - 0.31 11.3 3.6 0.94 9.8 3.6 1.8 1 0 0 1 1 1 0 Rab interacting lysosomal protein Atg14 PF10186.9 CBZ26584.1 - 1.4 8.0 9.1 2.1 7.3 9.1 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 CCDC-167 PF15188.6 CBZ26584.1 - 3.7 8.0 10.9 3.1 8.2 8.0 2.4 2 1 0 2 2 2 0 Coiled-coil domain-containing protein 167 UPF0242 PF06785.11 CBZ26584.1 - 3.8 7.6 14.6 14 5.7 14.6 2.0 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Spc7 PF08317.11 CBZ26584.1 - 4 6.2 21.6 0.46 9.3 12.3 2.0 1 1 1 2 2 2 0 Spc7 kinetochore protein DUF724 PF05266.14 CBZ26584.1 - 8.3 6.2 12.5 4.5 7.1 7.5 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF724) TPR_MLP1_2 PF07926.12 CBZ26584.1 - 8.8 6.4 25.8 3.4 7.7 15.3 3.3 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein CENP-F_leu_zip PF10473.9 CBZ26584.1 - 9 6.3 24.9 0.89 9.6 9.0 3.4 1 1 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 PKcGMP_CC PF16808.5 CBZ26584.1 - 9.4 6.2 9.5 25 4.8 0.0 3.6 3 0 0 3 3 3 0 Coiled-coil N-terminus of cGMP-dependent protein kinase TolA_bind_tri PF16331.5 CBZ26584.1 - 9.8 6.3 21.3 0.25 11.4 0.6 4.6 3 1 2 5 5 5 0 TolA binding protein trimerisation UT PF03253.14 CBZ26585.1 - 0.18 10.9 0.0 0.28 10.3 0.0 1.2 1 0 0 1 1 1 0 Urea transporter Cas_Csd1 PF09709.10 CBZ26588.1 - 0.063 12.0 0.0 0.12 11.1 0.0 1.3 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Csd1) Kelch_6 PF13964.6 CBZ26589.1 - 7.4e-27 92.7 10.8 2.9e-06 27.3 0.1 6.2 6 0 0 6 6 6 5 Kelch motif Kelch_1 PF01344.25 CBZ26589.1 - 3.6e-25 87.3 16.5 4.5e-08 32.6 0.1 6.4 6 0 0 6 6 6 5 Kelch motif Kelch_5 PF13854.6 CBZ26589.1 - 1.3e-19 69.7 13.7 6.2e-05 22.9 0.0 5.2 5 0 0 5 5 5 4 Kelch motif Kelch_3 PF13415.6 CBZ26589.1 - 4.3e-19 68.3 15.5 5e-05 23.5 0.0 7.0 7 0 0 7 7 7 4 Galactose oxidase, central domain Kelch_4 PF13418.6 CBZ26589.1 - 1.6e-18 66.5 1.7 4.5e-06 26.6 0.0 5.4 5 0 0 5 5 5 4 Galactose oxidase, central domain Kelch_2 PF07646.15 CBZ26589.1 - 1.6e-11 43.7 22.1 0.0053 16.7 0.2 6.8 7 1 0 7 7 7 4 Kelch motif PQQ_3 PF13570.6 CBZ26589.1 - 8 7.1 11.0 5.7 7.6 0.1 5.1 5 1 1 6 6 6 0 PQQ-like domain RIIa PF02197.17 CBZ26590.1 - 0.24 11.1 0.6 1 9.1 0.0 2.4 2 0 0 2 2 2 0 Regulatory subunit of type II PKA R-subunit DUF2267 PF10025.9 CBZ26590.1 - 6.1 7.2 10.1 0.96 9.7 0.5 3.5 3 1 0 3 3 3 0 Uncharacterized conserved protein (DUF2267) DS PF01916.17 CBZ26593.1 - 2.1e-87 293.0 0.0 2.6e-87 292.7 0.0 1.1 1 0 0 1 1 1 1 Deoxyhypusine synthase Peptidase_S49_N PF08496.10 CBZ26593.1 - 0.029 14.4 0.5 1.7 8.7 0.5 2.2 1 1 1 2 2 2 0 Peptidase family S49 N-terminal AAA_5 PF07728.14 CBZ26594.1 - 1.5e-123 407.2 0.0 3.9e-23 82.0 0.0 8.7 7 1 0 8 8 8 8 AAA domain (dynein-related subfamily) AAA_lid_7 PF17867.1 CBZ26594.1 - 4.7e-44 148.9 5.3 5.2e-13 49.1 0.1 5.3 4 0 0 4 4 4 4 Midasin AAA lid domain AAA_3 PF07726.11 CBZ26594.1 - 1.5e-26 92.8 0.0 0.0019 18.1 0.0 8.3 8 0 0 8 8 8 4 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 CBZ26594.1 - 1.3e-24 86.7 1.0 7e-05 22.4 0.0 6.5 6 0 0 6 6 6 5 P-loop containing dynein motor region AAA_lid_5 PF17865.1 CBZ26594.1 - 4.8e-22 78.0 0.0 1.7e-21 76.3 0.0 2.0 2 0 0 2 2 1 1 Midasin AAA lid domain AAA PF00004.29 CBZ26594.1 - 6e-21 75.2 0.1 0.00095 19.6 0.0 7.4 6 0 0 6 6 6 3 ATPase family associated with various cellular activities (AAA) AAA_6 PF12774.7 CBZ26594.1 - 1.4e-20 73.6 0.6 0.015 14.3 0.0 8.4 8 1 0 8 8 8 5 Hydrolytic ATP binding site of dynein motor region AAA_22 PF13401.6 CBZ26594.1 - 4.5e-20 72.3 0.5 0.0032 17.7 0.0 7.6 7 0 0 7 7 6 4 AAA domain AAA_16 PF13191.6 CBZ26594.1 - 2.6e-18 67.0 30.1 0.00015 22.2 0.0 10.7 11 1 0 11 11 8 5 AAA ATPase domain Dynein_heavy PF03028.15 CBZ26594.1 - 7.5e-18 64.8 0.1 0.031 14.4 0.0 6.3 6 0 0 6 6 5 4 Dynein heavy chain region D6 P-loop domain Sigma54_activat PF00158.26 CBZ26594.1 - 2e-16 60.2 0.2 0.011 15.5 0.0 6.5 6 0 0 6 6 6 3 Sigma-54 interaction domain AAA_14 PF13173.6 CBZ26594.1 - 6e-13 49.0 0.0 0.0068 16.4 0.0 6.4 5 0 0 5 5 5 2 AAA domain TsaE PF02367.17 CBZ26594.1 - 5.7e-12 45.7 4.7 0.015 15.3 0.1 6.5 6 0 0 6 6 6 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE Sigma54_activ_2 PF14532.6 CBZ26594.1 - 5.7e-11 42.7 0.3 0.001 19.2 0.0 5.6 6 0 0 6 6 6 2 Sigma-54 interaction domain AAA_18 PF13238.6 CBZ26594.1 - 1.6e-10 41.6 0.2 0.48 11.0 0.0 7.0 6 1 0 6 6 6 3 AAA domain ABC_tran PF00005.27 CBZ26594.1 - 8.4e-10 39.3 13.3 0.27 11.7 0.0 7.3 8 0 0 8 8 6 3 ABC transporter IstB_IS21 PF01695.17 CBZ26594.1 - 1.6e-09 37.7 0.2 0.11 12.2 0.0 4.8 5 0 0 5 5 4 3 IstB-like ATP binding protein AAA_29 PF13555.6 CBZ26594.1 - 2.5e-09 36.7 2.4 8.4 6.2 0.1 6.6 6 0 0 6 6 6 0 P-loop containing region of AAA domain Zeta_toxin PF06414.12 CBZ26594.1 - 5.5e-09 35.6 0.4 0.12 11.6 0.0 5.9 6 0 0 6 6 6 2 Zeta toxin RsgA_GTPase PF03193.16 CBZ26594.1 - 7.7e-09 35.7 1.6 1.4 8.8 0.0 5.8 5 0 0 5 5 5 2 RsgA GTPase DUF815 PF05673.13 CBZ26594.1 - 2.3e-08 33.5 3.0 0.18 10.9 0.0 5.4 6 0 0 6 6 5 2 Protein of unknown function (DUF815) T2SSE PF00437.20 CBZ26594.1 - 5.1e-08 32.3 1.6 0.15 11.1 0.0 6.1 6 0 0 6 6 6 2 Type II/IV secretion system protein Rad17 PF03215.15 CBZ26594.1 - 7.9e-08 32.4 1.0 5.2 6.9 0.0 6.2 6 0 0 6 6 6 0 Rad17 P-loop domain RNA_helicase PF00910.22 CBZ26594.1 - 1.9e-07 31.4 0.6 0.47 10.9 0.0 6.2 7 0 0 7 7 5 1 RNA helicase AAA_25 PF13481.6 CBZ26594.1 - 3.6e-07 30.0 3.5 0.52 9.8 0.0 6.2 6 0 0 6 6 5 1 AAA domain Mg_chelatase PF01078.21 CBZ26594.1 - 1.7e-06 27.6 2.9 8.5 5.7 0.0 7.4 9 0 0 9 9 7 0 Magnesium chelatase, subunit ChlI RuvB_N PF05496.12 CBZ26594.1 - 3.9e-06 26.7 0.4 0.56 9.9 0.0 5.6 7 0 0 7 7 5 1 Holliday junction DNA helicase RuvB P-loop domain AAA_33 PF13671.6 CBZ26594.1 - 9.3e-06 25.9 8.5 9 6.5 0.0 7.3 7 0 0 7 7 6 0 AAA domain NACHT PF05729.12 CBZ26594.1 - 1.5e-05 25.0 3.1 1.3 8.9 0.0 5.8 6 0 0 6 6 6 1 NACHT domain AAA_8 PF12780.7 CBZ26594.1 - 8.6e-05 22.0 0.4 1.6 8.0 0.0 4.9 6 0 0 6 6 5 1 P-loop containing dynein motor region D4 DAP3 PF10236.9 CBZ26594.1 - 0.00014 21.2 0.1 4.2 6.5 0.0 3.5 3 0 0 3 3 3 0 Mitochondrial ribosomal death-associated protein 3 NTPase_1 PF03266.15 CBZ26594.1 - 0.00063 19.7 1.3 1.4 8.8 0.0 4.3 4 0 0 4 4 4 1 NTPase MeaB PF03308.16 CBZ26594.1 - 0.001 18.1 1.7 0.35 9.8 0.1 3.5 3 0 0 3 3 3 1 Methylmalonyl Co-A mutase-associated GTPase MeaB CPT PF07931.12 CBZ26594.1 - 0.001 18.9 1.6 0.89 9.4 0.0 4.5 5 0 0 5 5 3 1 Chloramphenicol phosphotransferase-like protein TniB PF05621.11 CBZ26594.1 - 0.0023 17.3 0.1 0.54 9.6 0.0 4.4 5 0 0 5 5 4 1 Bacterial TniB protein AAA_19 PF13245.6 CBZ26594.1 - 0.0083 16.5 6.9 10 6.4 0.0 6.3 8 0 0 8 8 6 0 AAA domain ResIII PF04851.15 CBZ26594.1 - 0.0092 16.0 4.8 1.2 9.2 0.0 4.8 6 0 0 6 6 4 1 Type III restriction enzyme, res subunit dNK PF01712.19 CBZ26594.1 - 0.029 14.2 1.1 19 5.0 0.0 4.1 4 0 0 4 4 4 0 Deoxynucleoside kinase VWA_3 PF13768.6 CBZ26594.1 - 0.032 14.2 0.1 0.13 12.2 0.1 2.1 1 0 0 1 1 1 0 von Willebrand factor type A domain ATPase_2 PF01637.18 CBZ26594.1 - 0.038 13.9 0.0 9.4 6.1 0.0 3.9 4 0 0 4 4 4 0 ATPase domain predominantly from Archaea PduV-EutP PF10662.9 CBZ26594.1 - 0.047 13.4 0.4 44 3.8 0.0 4.4 6 0 0 6 6 3 0 Ethanolamine utilisation - propanediol utilisation TIP49 PF06068.13 CBZ26594.1 - 0.055 12.7 1.4 8.7 5.4 0.1 3.9 5 0 0 5 5 4 0 TIP49 P-loop domain AAA_21 PF13304.6 CBZ26594.1 - 0.07 12.9 0.0 0.87 9.3 0.0 2.9 3 0 0 3 3 2 0 AAA domain, putative AbiEii toxin, Type IV TA system PhoH PF02562.16 CBZ26594.1 - 0.42 10.0 7.5 6.5 6.1 0.0 4.3 5 0 0 5 5 4 0 PhoH-like protein Roc PF08477.13 CBZ26594.1 - 0.55 10.5 2.2 56 4.0 0.0 4.4 5 0 0 5 5 4 0 Ras of Complex, Roc, domain of DAPkinase SRP54 PF00448.22 CBZ26594.1 - 1.1 8.9 6.1 1e+02 2.5 0.2 4.9 5 0 0 5 5 5 0 SRP54-type protein, GTPase domain Enkurin PF13864.6 CBZ26596.1 - 6.9e-18 64.9 4.8 1.1e-17 64.2 4.8 1.4 1 0 0 1 1 1 1 Calmodulin-binding GPS2_interact PF15784.5 CBZ26596.1 - 0.74 10.3 4.6 0.67 10.4 2.5 2.0 1 1 1 2 2 2 0 G-protein pathway suppressor 2-interacting domain BCDHK_Adom3 PF10436.9 CBZ26597.1 - 1.1e-20 74.1 0.1 1.7e-20 73.5 0.1 1.3 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.26 CBZ26597.1 - 3.3e-10 40.4 0.0 8.8e-09 35.9 0.0 2.3 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 CBZ26597.1 - 3.2e-05 23.8 0.0 6.4e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase ZZ PF00569.17 CBZ26598.1 - 3.5e-07 29.9 8.9 3.5e-07 29.9 8.9 2.9 2 0 0 2 2 2 1 Zinc finger, ZZ type C1_2 PF03107.16 CBZ26598.1 - 0.011 16.1 0.5 0.011 16.1 0.5 2.7 2 0 0 2 2 2 0 C1 domain Psu PF07455.11 CBZ26598.1 - 0.099 12.2 0.2 0.19 11.3 0.2 1.4 1 0 0 1 1 1 0 Phage polarity suppression protein (Psu) zinc-ribbons_6 PF07191.12 CBZ26598.1 - 2.7 8.0 15.7 0.6 10.1 3.4 3.0 3 0 0 3 3 3 0 zinc-ribbons LRR_6 PF13516.6 CBZ26599.1 - 0.00021 21.1 0.9 0.035 14.2 0.0 3.6 4 0 0 4 4 4 1 Leucine Rich repeat LRR_4 PF12799.7 CBZ26599.1 - 0.015 15.7 1.2 6.9 7.2 0.0 3.2 3 0 0 3 3 3 0 Leucine Rich repeats (2 copies) LRR_4 PF12799.7 CBZ26601.1 - 1.3e-13 50.8 18.1 2.8e-05 24.4 1.9 5.2 3 2 2 5 5 5 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CBZ26601.1 - 9.5e-12 44.5 14.8 1.7e-06 27.7 1.5 3.8 2 1 1 3 3 3 3 Leucine rich repeat LRR_6 PF13516.6 CBZ26601.1 - 0.00036 20.3 16.6 2.5 8.4 0.4 7.2 7 0 0 7 7 7 2 Leucine Rich repeat LRR_1 PF00560.33 CBZ26601.1 - 0.00051 20.2 16.0 3.9 8.4 0.1 7.2 6 1 0 6 6 6 1 Leucine Rich Repeat LRR_9 PF14580.6 CBZ26601.1 - 0.1 12.1 1.8 3.9 6.9 0.3 2.9 2 1 0 2 2 2 0 Leucine-rich repeat Acetyltransf_13 PF13880.6 CBZ26605.1 - 2.8e-21 75.2 0.0 5.2e-21 74.4 0.0 1.4 1 0 0 1 1 1 1 ESCO1/2 acetyl-transferase Acetyltransf_7 PF13508.7 CBZ26605.1 - 0.029 14.8 0.0 0.33 11.4 0.0 2.2 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 CBZ26605.1 - 0.097 12.9 0.0 12 6.2 0.0 2.3 2 0 0 2 2 2 0 Acetyltransferase (GNAT) family MFS_1 PF07690.16 CBZ26606.1 - 5e-21 75.0 30.6 1e-14 54.2 9.0 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 CBZ26606.1 - 0.00015 20.8 37.2 0.0014 17.5 11.3 2.9 2 1 1 3 3 3 3 Sugar (and other) transporter Use1 PF09753.9 CBZ26606.1 - 1.6 8.4 4.7 0.47 10.1 1.3 1.8 1 1 1 2 2 2 0 Membrane fusion protein Use1 ATPase_gene1 PF09527.10 CBZ26606.1 - 4 7.7 7.0 0.54 10.5 1.4 2.5 2 0 0 2 2 2 0 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter DUF2946 PF11162.8 CBZ26608.1 - 3.9e-12 46.8 0.1 2.4e-11 44.3 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF2946) DUF4381 PF14316.6 CBZ26608.1 - 0.0024 18.1 0.0 0.0098 16.1 0.0 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF4381) Vpu PF00558.19 CBZ26608.1 - 0.0049 16.6 0.4 0.013 15.3 0.4 1.6 1 0 0 1 1 1 1 Vpu protein TMEM174 PF15029.6 CBZ26608.1 - 0.0093 15.7 0.2 0.015 15.0 0.2 1.2 1 0 0 1 1 1 1 Transmembrane protein 174 EphA2_TM PF14575.6 CBZ26608.1 - 0.0098 16.7 0.1 0.064 14.1 0.0 2.0 2 0 0 2 2 2 1 Ephrin type-A receptor 2 transmembrane domain Shisa PF13908.6 CBZ26608.1 - 0.016 15.4 0.0 0.028 14.7 0.0 1.4 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator ECSCR PF15820.5 CBZ26608.1 - 0.018 14.9 0.1 0.035 13.9 0.1 1.4 1 0 0 1 1 1 0 Endothelial cell-specific chemotaxis regulator TMEM154 PF15102.6 CBZ26608.1 - 0.025 14.5 0.0 0.04 13.8 0.0 1.2 1 0 0 1 1 1 0 TMEM154 protein family DUF4307 PF14155.6 CBZ26608.1 - 0.025 14.4 0.3 1.6 8.6 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4307) MAP17 PF15807.5 CBZ26608.1 - 0.031 14.5 0.0 0.052 13.8 0.0 1.3 1 0 0 1 1 1 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 TMIE PF16038.5 CBZ26608.1 - 0.044 13.6 0.4 0.074 12.9 0.4 1.3 1 0 0 1 1 1 0 TMIE protein Cadherin_C_2 PF16492.5 CBZ26608.1 - 0.048 14.4 0.0 0.68 10.7 0.0 2.2 2 0 0 2 2 2 0 Cadherin cytoplasmic C-terminal Prominin PF05478.11 CBZ26608.1 - 0.15 10.0 0.1 0.19 9.6 0.1 1.1 1 0 0 1 1 1 0 Prominin DUF4006 PF13179.6 CBZ26608.1 - 0.72 9.8 3.9 15 5.6 0.1 2.4 2 0 0 2 2 2 0 Family of unknown function (DUF4006) Metallophos PF00149.28 CBZ26609.1 - 0.0082 16.7 0.1 0.05 14.1 0.0 2.4 2 1 0 2 2 2 1 Calcineurin-like phosphoesterase EI24 PF07264.11 CBZ26609.1 - 2.5 8.3 23.5 0.013 15.7 8.2 3.1 2 2 0 2 2 2 0 Etoposide-induced protein 2.4 (EI24) Metallophos PF00149.28 CBZ26610.1 - 0.0064 17.0 0.0 0.028 14.9 0.0 2.0 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase NUDIX PF00293.28 CBZ26611.1 - 0.00071 19.6 1.6 2.4 8.2 0.0 3.7 3 1 0 4 4 4 3 NUDIX domain Rad1 PF02144.16 CBZ26612.1 - 7.8e-06 25.2 0.0 0.0072 15.4 0.0 2.1 2 0 0 2 2 2 2 Repair protein Rad1/Rec1/Rad17 Methyltransf_8 PF05148.15 CBZ26615.1 - 5.8e-53 180.0 0.0 7.7e-53 179.6 0.0 1.2 1 0 0 1 1 1 1 Hypothetical methyltransferase Methyltransf_11 PF08241.12 CBZ26615.1 - 1.1e-06 29.2 0.1 8.2e-06 26.4 0.1 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CBZ26615.1 - 2.7e-05 24.8 0.1 0.1 13.4 0.0 2.8 1 1 1 2 2 2 2 Methyltransferase domain Ubie_methyltran PF01209.18 CBZ26615.1 - 0.0033 16.8 0.1 0.018 14.3 0.0 2.1 1 1 2 3 3 3 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.6 CBZ26615.1 - 0.023 14.5 0.0 0.095 12.5 0.0 1.9 1 1 0 1 1 1 0 Methyltransferase domain IHABP4_N PF16174.5 CBZ26615.1 - 0.3 11.7 9.1 0.46 11.1 9.1 1.3 1 0 0 1 1 1 0 Intracellular hyaluronan-binding protein 4 N-terminal DUF4603 PF15376.6 CBZ26615.1 - 4.8 4.4 7.0 6.4 4.0 7.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4603) DAO PF01266.24 CBZ26616.1 - 6.9e-18 65.4 0.4 4.7e-15 56.0 0.4 3.8 1 1 0 1 1 1 1 FAD dependent oxidoreductase DAO_C PF16901.5 CBZ26616.1 - 3.3e-09 36.7 0.2 7.5e-09 35.5 0.2 1.6 1 0 0 1 1 1 1 C-terminal domain of alpha-glycerophosphate oxidase FAD_binding_2 PF00890.24 CBZ26616.1 - 6e-07 28.9 1.4 7e-07 28.7 0.2 1.7 2 0 0 2 2 2 1 FAD binding domain GIDA PF01134.22 CBZ26616.1 - 4e-06 26.2 0.5 1.7e-05 24.1 0.0 2.0 2 0 0 2 2 2 1 Glucose inhibited division protein A FAD_oxidored PF12831.7 CBZ26616.1 - 3.5e-05 23.4 0.5 6.1e-05 22.5 0.5 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 CBZ26616.1 - 0.00019 21.6 0.4 0.00053 20.2 0.4 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 CBZ26616.1 - 0.00043 19.1 0.1 0.00064 18.5 0.1 1.2 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_2 PF07992.14 CBZ26616.1 - 0.00059 19.2 0.0 0.00098 18.4 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 CBZ26616.1 - 1.5 9.4 4.9 0.47 11.1 0.2 2.5 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase AIG2_2 PF13772.6 CBZ26617.1 - 7.7e-09 35.8 0.2 4.9e-08 33.3 0.1 2.4 3 0 0 3 3 3 1 AIG2-like family GGACT PF06094.12 CBZ26617.1 - 1.1e-08 35.7 0.0 9.6e-07 29.4 0.0 3.0 2 2 0 2 2 2 1 Gamma-glutamyl cyclotransferase, AIG2-like HgmA PF04209.13 CBZ26617.1 - 0.11 11.1 0.1 1.3 7.6 0.1 2.0 2 0 0 2 2 2 0 homogentisate 1,2-dioxygenase DUF2618 PF10940.8 CBZ26618.1 - 0.011 15.6 0.1 0.024 14.4 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2618) TM231 PF10149.9 CBZ26619.1 - 8.1e-26 91.1 3.5 4e-15 56.0 0.0 2.2 2 0 0 2 2 2 2 Transmembrane protein 231 EF-hand_1 PF00036.32 CBZ26619.1 - 0.11 12.1 0.2 0.21 11.2 0.2 1.5 1 0 0 1 1 1 0 EF hand Tubulin PF00091.25 CBZ26620.1 - 7.3e-29 101.4 0.0 6.2e-14 52.6 0.0 2.9 2 1 0 2 2 2 2 Tubulin/FtsZ family, GTPase domain Tubulin_2 PF13809.6 CBZ26620.1 - 0.003 16.8 0.0 0.0051 16.0 0.0 1.2 1 0 0 1 1 1 1 Tubulin like PKS_DE PF18369.1 CBZ26620.1 - 0.055 14.0 0.4 0.86 10.2 0.2 2.7 2 0 0 2 2 2 0 Polyketide synthase dimerisation element domain MEIOC PF15189.6 CBZ26620.1 - 0.082 12.5 1.1 0.15 11.7 1.1 1.4 1 0 0 1 1 1 0 Meiosis-specific coiled-coil domain-containing protein MEIOC PPR_2 PF13041.6 CBZ26621.1 - 1.4e-12 47.6 0.1 0.00033 20.8 0.0 4.2 3 1 1 4 4 4 3 PPR repeat family PPR PF01535.20 CBZ26621.1 - 4.6e-09 35.9 0.8 0.028 14.7 0.1 4.2 4 0 0 4 4 4 3 PPR repeat PPR_3 PF13812.6 CBZ26621.1 - 8.9e-06 25.7 0.0 0.00047 20.2 0.0 2.6 3 0 0 3 3 3 1 Pentatricopeptide repeat domain PPR_long PF17177.4 CBZ26621.1 - 0.00016 21.1 0.6 0.021 14.2 0.1 2.1 1 1 1 2 2 2 2 Pentacotripeptide-repeat region of PRORP PPR_1 PF12854.7 CBZ26621.1 - 0.011 15.4 0.0 0.48 10.2 0.0 2.8 2 0 0 2 2 2 0 PPR repeat A2L_zn_ribbon PF08792.10 CBZ26622.1 - 0.0087 15.8 0.3 0.014 15.1 0.3 1.3 1 0 0 1 1 1 1 A2L zinc ribbon domain zinc_ribbon_10 PF10058.9 CBZ26622.1 - 0.024 14.4 0.0 6.7 6.5 0.0 2.2 2 0 0 2 2 2 0 Predicted integral membrane zinc-ribbon metal-binding protein Zn_Tnp_IS91 PF14319.6 CBZ26622.1 - 0.029 14.4 0.1 0.033 14.2 0.1 1.1 1 0 0 1 1 1 0 Transposase zinc-binding domain PhnA_Zn_Ribbon PF08274.12 CBZ26622.1 - 0.041 13.8 1.0 6 6.9 0.0 2.2 2 0 0 2 2 2 0 PhnA Zinc-Ribbon zf-LSD1 PF06943.12 CBZ26622.1 - 0.045 13.6 1.1 0.045 13.6 1.1 1.8 2 0 0 2 2 2 0 LSD1 zinc finger DNA_RNApol_7kD PF03604.13 CBZ26622.1 - 0.066 12.9 1.7 0.13 11.9 1.7 1.6 1 1 0 1 1 1 0 DNA directed RNA polymerase, 7 kDa subunit TF_Zn_Ribbon PF08271.12 CBZ26622.1 - 0.07 12.7 1.0 3.4 7.3 0.1 2.3 2 0 0 2 2 2 0 TFIIB zinc-binding DUF2318 PF10080.9 CBZ26622.1 - 0.1 12.8 0.3 0.11 12.6 0.3 1.3 1 1 0 1 1 1 0 Predicted membrane protein (DUF2318) Nudix_N_2 PF14803.6 CBZ26622.1 - 0.95 9.4 5.6 16 5.5 5.7 2.3 1 1 1 2 2 2 0 Nudix N-terminal CTP_transf_like PF01467.26 CBZ26623.1 - 9.1e-06 25.9 0.0 9.8e-05 22.6 0.0 2.3 1 1 0 1 1 1 1 Cytidylyltransferase-like Ribosomal_S15 PF00312.22 CBZ26624.1 - 2.9e-07 30.6 1.6 6.3e-07 29.5 1.6 1.5 1 0 0 1 1 1 1 Ribosomal protein S15 DUF4404 PF14357.6 CBZ26624.1 - 0.2 12.3 1.1 2 9.1 0.0 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4404) MORN PF02493.20 CBZ26625.1 - 1.7e-18 65.3 17.1 8.7e-06 25.3 0.1 6.8 7 0 0 7 7 7 4 MORN repeat WW PF00397.26 CBZ26625.1 - 0.0066 16.5 0.4 0.017 15.2 0.4 1.7 1 0 0 1 1 1 1 WW domain Endonuc_Holl PF10107.9 CBZ26626.1 - 0.053 13.4 0.0 0.075 12.9 0.0 1.3 1 0 0 1 1 1 0 Endonuclease related to archaeal Holliday junction resolvase RWD PF05773.22 CBZ26627.1 - 9.5e-11 42.0 0.5 1.6e-10 41.3 0.5 1.4 1 0 0 1 1 1 1 RWD domain DFRP_C PF16543.5 CBZ26627.1 - 3.4e-06 27.5 1.8 6.3e-06 26.6 1.8 1.5 1 0 0 1 1 1 1 DRG Family Regulatory Proteins, Tma46 phage_tail_N PF08400.10 CBZ26627.1 - 0.07 13.1 0.8 0.18 11.8 0.3 1.8 1 1 0 2 2 2 0 Prophage tail fibre N-terminal DnaJ_C PF01556.18 CBZ26628.1 - 5.6e-18 65.5 0.0 8.1e-18 64.9 0.0 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.19 CBZ26628.1 - 3.2e-09 37.0 10.4 7.4e-09 35.9 10.4 1.7 1 0 0 1 1 1 1 DnaJ central domain Anti-TRAP PF15777.5 CBZ26628.1 - 0.071 13.1 18.9 0.12 12.3 2.6 3.1 2 1 1 3 3 3 0 Tryptophan RNA-binding attenuator protein inhibitory protein CTP_synth_N PF06418.14 CBZ26629.1 - 1.3e-106 355.7 0.0 1.7e-106 355.4 0.0 1.1 1 0 0 1 1 1 1 CTP synthase N-terminus GATase PF00117.28 CBZ26629.1 - 1.6e-45 155.2 0.0 5.3e-45 153.5 0.0 1.8 2 0 0 2 2 2 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 CBZ26629.1 - 3.3e-07 30.3 0.1 2.4e-06 27.5 0.1 2.3 2 1 0 2 2 2 1 Peptidase C26 CbiA PF01656.23 CBZ26629.1 - 0.011 15.8 0.0 0.026 14.6 0.0 1.7 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain MORN PF02493.20 CBZ26631.1 - 4.9e-23 79.6 37.3 1.2e-06 28.0 0.3 6.7 7 0 0 7 7 7 6 MORN repeat Podoplanin PF05808.11 CBZ26631.1 - 0.5 10.5 0.0 0.5 10.5 0.0 2.3 2 1 0 2 2 2 0 Podoplanin NTP_transf_2 PF01909.23 CBZ26633.1 - 0.0027 18.0 0.0 0.0052 17.0 0.0 1.5 1 0 0 1 1 1 1 Nucleotidyltransferase domain Polbeta PF18765.1 CBZ26633.1 - 0.11 12.6 0.0 0.23 11.6 0.0 1.5 1 0 0 1 1 1 0 Polymerase beta, Nucleotidyltransferase Kinesin PF00225.23 CBZ26636.1 - 1.6e-79 267.3 2.4 3.8e-73 246.3 0.0 3.0 3 0 0 3 3 3 2 Kinesin motor domain Microtub_bd PF16796.5 CBZ26636.1 - 3.2e-09 36.9 0.4 0.0015 18.5 0.0 2.6 2 0 0 2 2 2 2 Microtubule binding Peptidase_C58 PF03543.14 CBZ26636.1 - 0.12 12.1 2.0 0.43 10.3 2.0 2.0 1 0 0 1 1 1 0 Yersinia/Haemophilus virulence surface antigen Fib_alpha PF08702.10 CBZ26636.1 - 0.28 11.4 6.3 13 6.0 0.5 3.5 3 0 0 3 3 3 0 Fibrinogen alpha/beta chain family UPF0242 PF06785.11 CBZ26636.1 - 3 7.9 33.6 0.058 13.5 3.9 4.1 4 0 0 4 4 4 0 Uncharacterised protein family (UPF0242) N-terminus APG6_N PF17675.1 CBZ26636.1 - 4.8 7.7 32.1 0.13 12.8 8.8 4.2 3 1 1 4 4 4 0 Apg6 coiled-coil region TPR_14 PF13428.6 CBZ26637.1 - 0.00014 22.4 9.0 7 7.8 0.1 5.9 2 1 4 6 6 6 2 Tetratricopeptide repeat Suf PF05843.14 CBZ26637.1 - 0.0031 17.5 1.8 1 9.3 0.0 3.2 2 2 0 2 2 2 2 Suppressor of forked protein (Suf) NRDE-2 PF08424.10 CBZ26637.1 - 0.046 12.8 0.2 1.3 8.0 0.1 2.3 2 0 0 2 2 2 0 NRDE-2, necessary for RNA interference TPR_2 PF07719.17 CBZ26637.1 - 0.41 10.9 3.5 46 4.5 0.2 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat HEAT PF02985.22 CBZ26638.1 - 1.6e-23 80.7 44.6 0.0033 17.6 0.1 13.3 14 0 0 14 14 14 8 HEAT repeat HEAT_2 PF13646.6 CBZ26638.1 - 1.6e-22 79.7 23.6 3.3e-07 30.6 0.1 7.8 3 3 4 7 7 7 7 HEAT repeats HEAT_EZ PF13513.6 CBZ26638.1 - 3.6e-07 30.6 25.2 0.008 16.7 0.0 7.8 7 3 3 10 10 10 4 HEAT-like repeat Cnd1 PF12717.7 CBZ26638.1 - 9e-07 29.1 10.6 0.012 15.7 0.1 5.2 2 1 3 6 6 6 2 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.7 CBZ26638.1 - 1.2e-06 29.0 0.1 0.012 16.1 0.0 5.6 3 1 2 6 6 6 1 Vacuolar 14 Fab1-binding region Adaptin_N PF01602.20 CBZ26638.1 - 0.0003 19.5 6.1 0.07 11.7 5.0 3.3 2 1 0 3 3 3 2 Adaptin N terminal region CLASP_N PF12348.8 CBZ26638.1 - 0.00047 19.8 2.5 0.2 11.2 0.7 3.9 1 1 3 4 4 4 2 CLASP N terminal TAF6_C PF07571.13 CBZ26638.1 - 0.11 12.8 0.2 6.3 7.2 0.0 3.7 3 1 0 3 3 3 0 TAF6 C-terminal HEAT repeat domain Acyl-CoA_dh_C PF12806.7 CBZ26639.1 - 0.0058 16.8 1.1 0.011 15.9 1.1 1.5 1 1 0 1 1 1 1 Acetyl-CoA dehydrogenase C-terminal like Tfb2 PF03849.14 CBZ26639.1 - 0.01 14.9 2.3 0.014 14.4 2.3 1.2 1 0 0 1 1 1 0 Transcription factor Tfb2 Lactococcin_972 PF09683.10 CBZ26639.1 - 0.014 15.9 0.8 0.014 15.9 0.8 1.7 2 0 0 2 2 2 0 Bacteriocin (Lactococcin_972) DUF775 PF05603.12 CBZ26640.1 - 5.7e-21 75.0 0.0 1.1e-20 74.0 0.0 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF775) PNISR PF15996.5 CBZ26641.1 - 0.1 12.9 0.0 0.1 12.9 0.0 4.6 3 1 1 4 4 4 0 Arginine/serine-rich protein PNISR Pkinase PF00069.25 CBZ26644.1 - 2.5e-56 191.0 0.0 3.7e-56 190.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ26644.1 - 2.7e-36 125.2 0.0 4.1e-36 124.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase cNMP_binding PF00027.29 CBZ26644.1 - 6.9e-15 54.9 0.1 8.9e-08 32.1 0.1 3.7 3 0 0 3 3 3 3 Cyclic nucleotide-binding domain PAS PF00989.25 CBZ26644.1 - 4.7e-07 29.8 0.3 1.6e-06 28.1 0.0 2.0 2 0 0 2 2 2 1 PAS fold PAS_9 PF13426.7 CBZ26644.1 - 5e-06 26.7 0.0 1.1e-05 25.7 0.0 1.5 1 0 0 1 1 1 1 PAS domain Kinase-like PF14531.6 CBZ26644.1 - 0.00033 20.1 0.0 0.0047 16.3 0.0 2.1 2 0 0 2 2 2 1 Kinase-like PAS_4 PF08448.10 CBZ26644.1 - 0.0034 17.6 0.1 0.022 15.0 0.0 2.5 3 0 0 3 3 3 1 PAS fold PAS_3 PF08447.12 CBZ26644.1 - 0.0035 17.6 0.0 0.0086 16.3 0.0 1.7 1 0 0 1 1 1 1 PAS fold Tubulin_3 PF14881.6 CBZ26645.1 - 1.3e-05 25.0 0.0 2.9e-05 23.8 0.0 1.6 1 0 0 1 1 1 1 Tubulin domain Misat_Tub_SegII PF10644.9 CBZ26645.1 - 0.00076 19.8 0.0 0.0015 18.8 0.0 1.5 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain CDC45 PF02724.14 CBZ26645.1 - 0.49 8.6 4.8 0.76 8.0 4.8 1.2 1 0 0 1 1 1 0 CDC45-like protein TTL PF03133.15 CBZ26646.1 - 5e-48 163.7 0.0 2e-45 155.2 0.0 2.5 1 1 0 1 1 1 1 Tubulin-tyrosine ligase family Snf7 PF03357.21 CBZ26647.1 - 0.0029 17.2 1.4 0.0029 17.2 1.4 4.3 2 2 2 4 4 4 1 Snf7 CNDH2_C PF16858.5 CBZ26647.1 - 0.0086 16.0 10.9 0.0086 16.0 10.9 2.3 2 1 0 2 2 2 1 Condensin II complex subunit CAP-H2 or CNDH2, C-term MHB PF16525.5 CBZ26647.1 - 1.4 9.2 13.6 1.5 9.1 0.3 3.8 3 1 0 3 3 3 0 Haemophore, haem-binding AAA PF00004.29 CBZ26648.1 - 3.2e-49 166.7 0.0 1.8e-36 125.5 0.0 2.8 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 CBZ26648.1 - 2.8e-09 36.6 0.0 6.9e-09 35.4 0.0 1.7 1 0 0 1 1 1 1 AAA+ lid domain AAA_22 PF13401.6 CBZ26648.1 - 3.3e-09 37.1 0.8 0.057 13.7 0.0 4.5 2 2 2 4 4 4 2 AAA domain AAA_16 PF13191.6 CBZ26648.1 - 6.4e-08 33.2 0.1 0.0088 16.4 0.0 3.3 2 1 0 2 2 2 2 AAA ATPase domain AAA_18 PF13238.6 CBZ26648.1 - 1.2e-07 32.3 0.1 0.024 15.2 0.0 2.9 3 1 0 3 3 2 2 AAA domain AAA_5 PF07728.14 CBZ26648.1 - 2.2e-07 31.0 0.0 0.0027 17.7 0.0 2.7 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) TIP49 PF06068.13 CBZ26648.1 - 3.6e-06 26.4 0.0 0.027 13.7 0.0 2.4 2 0 0 2 2 2 2 TIP49 P-loop domain Mg_chelatase PF01078.21 CBZ26648.1 - 1.2e-05 24.8 0.0 0.0029 17.0 0.1 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI RuvB_N PF05496.12 CBZ26648.1 - 6.6e-05 22.7 0.0 0.036 13.8 0.0 2.8 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain RNA_helicase PF00910.22 CBZ26648.1 - 0.00023 21.5 0.0 0.23 11.9 0.0 2.7 2 0 0 2 2 2 1 RNA helicase NACHT PF05729.12 CBZ26648.1 - 0.00032 20.7 0.1 0.36 10.7 0.0 3.7 3 1 0 3 3 3 1 NACHT domain AAA_7 PF12775.7 CBZ26648.1 - 0.00046 19.8 0.0 0.0056 16.2 0.0 2.3 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_3 PF07726.11 CBZ26648.1 - 0.00052 19.9 0.0 0.28 11.0 0.0 2.5 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 CBZ26648.1 - 0.00053 19.7 0.0 0.59 9.8 0.0 2.9 3 0 0 3 3 2 1 AAA domain Sigma54_activat PF00158.26 CBZ26648.1 - 0.00055 19.7 0.0 0.28 10.9 0.0 2.5 2 0 0 2 2 2 1 Sigma-54 interaction domain IstB_IS21 PF01695.17 CBZ26648.1 - 0.00068 19.4 0.0 0.14 11.8 0.0 2.5 2 0 0 2 2 2 1 IstB-like ATP binding protein Sigma54_activ_2 PF14532.6 CBZ26648.1 - 0.00099 19.2 0.0 0.99 9.5 0.0 2.6 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_17 PF13207.6 CBZ26648.1 - 0.001 19.5 0.0 1.1 9.6 0.0 3.0 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.6 CBZ26648.1 - 0.0012 19.1 0.0 2 8.6 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_33 PF13671.6 CBZ26648.1 - 0.0013 18.9 0.0 0.91 9.7 0.0 2.7 2 0 0 2 2 2 1 AAA domain DUF2075 PF09848.9 CBZ26648.1 - 0.0031 16.8 0.4 3.8 6.7 0.0 2.8 2 1 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) AAA_2 PF07724.14 CBZ26648.1 - 0.0033 17.6 0.0 0.017 15.2 0.0 2.2 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_24 PF13479.6 CBZ26648.1 - 0.0039 17.0 0.0 0.071 12.8 0.0 2.6 2 0 0 2 2 2 1 AAA domain TsaE PF02367.17 CBZ26648.1 - 0.004 17.1 0.0 0.24 11.4 0.0 2.3 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_19 PF13245.6 CBZ26648.1 - 0.0054 17.1 1.0 1.2 9.4 0.1 3.3 4 0 0 4 4 3 1 AAA domain AAA_11 PF13086.6 CBZ26648.1 - 0.006 16.4 0.0 0.63 9.8 0.0 2.5 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.12 CBZ26648.1 - 0.0092 15.3 0.1 0.57 9.4 0.0 2.4 2 0 0 2 2 2 1 Zeta toxin ATPase_2 PF01637.18 CBZ26648.1 - 0.014 15.4 0.1 8 6.3 0.1 3.1 2 2 1 3 3 3 0 ATPase domain predominantly from Archaea ABC_tran PF00005.27 CBZ26648.1 - 0.016 15.7 0.1 1.1 9.8 0.0 3.0 2 1 1 3 3 3 0 ABC transporter DUF1599 PF07659.11 CBZ26648.1 - 0.021 15.2 0.1 0.055 13.9 0.1 1.7 1 0 0 1 1 1 0 Nucleotide modification associated domain 1 Cytidylate_kin PF02224.18 CBZ26648.1 - 0.022 14.5 0.0 1 9.0 0.0 2.4 2 0 0 2 2 2 0 Cytidylate kinase ResIII PF04851.15 CBZ26648.1 - 0.027 14.5 0.0 9.8 6.1 0.0 3.1 2 1 0 3 3 3 0 Type III restriction enzyme, res subunit ATPase PF06745.13 CBZ26648.1 - 0.032 13.6 0.1 1.8 7.8 0.1 2.4 2 0 0 2 2 2 0 KaiC T2SSE PF00437.20 CBZ26648.1 - 0.037 13.1 0.0 5.6 5.9 0.0 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein KTI12 PF08433.10 CBZ26648.1 - 0.049 13.1 0.0 8.8 5.7 0.0 2.7 3 0 0 3 3 3 0 Chromatin associated protein KTI12 AAA_29 PF13555.6 CBZ26648.1 - 0.067 13.0 0.3 7.5 6.4 0.0 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_25 PF13481.6 CBZ26648.1 - 0.071 12.7 1.2 3.3 7.2 0.0 3.1 3 0 0 3 3 3 0 AAA domain PhoH PF02562.16 CBZ26648.1 - 0.073 12.5 0.0 1.3 8.4 0.0 2.4 2 0 0 2 2 2 0 PhoH-like protein NB-ARC PF00931.22 CBZ26648.1 - 0.078 12.2 0.0 2.7 7.1 0.0 2.3 2 0 0 2 2 2 0 NB-ARC domain CPT PF07931.12 CBZ26648.1 - 0.097 12.5 0.0 1.5 8.7 0.0 2.3 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein CDC48_N PF02359.18 CBZ26648.1 - 0.13 12.5 0.0 0.83 9.9 0.0 2.4 1 1 0 1 1 1 0 Cell division protein 48 (CDC48), N-terminal domain Sec16_C PF12931.7 CBZ26649.1 - 0.014 15.1 0.0 0.018 14.7 0.0 1.2 1 0 0 1 1 1 0 Sec23-binding domain of Sec16 ACPS PF01648.20 CBZ26650.1 - 1.2e-12 47.9 0.0 2.1e-12 47.2 0.0 1.4 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily SCO1-SenC PF02630.14 CBZ26651.1 - 3.4e-30 104.7 0.1 1.1e-25 90.0 0.0 2.3 1 1 1 2 2 2 2 SCO1/SenC Thioredoxin_8 PF13905.6 CBZ26651.1 - 0.0088 16.3 0.0 0.016 15.5 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin-like TruD PF01142.18 CBZ26652.1 - 3.5e-12 45.9 0.0 3e-07 29.6 0.0 3.2 3 0 0 3 3 3 2 tRNA pseudouridine synthase D (TruD) DEAD PF00270.29 CBZ26654.1 - 5.4e-30 104.4 0.4 5.1e-16 58.9 0.1 2.6 2 1 0 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.31 CBZ26654.1 - 3.1e-15 56.5 0.0 9.8e-15 54.9 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 CBZ26654.1 - 1.6e-08 34.7 0.0 1.2e-07 31.9 0.0 2.1 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit TniB PF05621.11 CBZ26654.1 - 0.028 13.8 0.1 0.064 12.7 0.1 1.5 1 0 0 1 1 1 0 Bacterial TniB protein AAA_22 PF13401.6 CBZ26654.1 - 0.047 14.0 0.5 6.7 7.0 0.2 2.7 2 0 0 2 2 2 0 AAA domain Elf1 PF05129.13 CBZ26655.1 - 1e-18 67.2 0.4 1.5e-18 66.6 0.4 1.3 1 0 0 1 1 1 1 Transcription elongation factor Elf1 like Elf1 PF05129.13 CBZ26656.1 - 7.1e-13 48.4 0.3 1.2e-12 47.7 0.3 1.4 1 0 0 1 1 1 1 Transcription elongation factor Elf1 like Ribonuclease_3 PF00636.26 CBZ26657.1 - 4.9e-06 27.1 0.0 1.2e-05 25.8 0.0 1.7 1 0 0 1 1 1 1 Ribonuclease III domain PAP2 PF01569.21 CBZ26657.1 - 0.13 12.0 0.5 0.38 10.5 0.1 1.9 2 0 0 2 2 2 0 PAP2 superfamily Hid1 PF12722.7 CBZ26658.1 - 1.8 6.6 3.8 1.9 6.5 3.8 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein AATF-Che1 PF13339.6 CBZ26659.1 - 9.7e-15 55.5 1.8 3.4e-14 53.7 0.0 2.8 3 0 0 3 3 3 1 Apoptosis antagonizing transcription factor TRAUB PF08164.12 CBZ26659.1 - 3.4e-05 24.3 0.0 3.4e-05 24.3 0.0 2.7 3 0 0 3 3 3 1 Apoptosis-antagonizing transcription factor, C-terminal PBP1_TM PF14812.6 CBZ26661.1 - 1.5 9.3 4.7 3.6 8.0 4.7 1.6 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF4379 PF14311.6 CBZ26662.1 - 1.2e-16 60.8 12.4 6.8e-10 39.2 8.4 2.6 2 0 0 2 2 2 2 Probable Zinc-ribbon domain DUF5631 PF18645.1 CBZ26662.1 - 0.0013 19.1 0.1 0.0055 17.0 0.1 2.1 1 0 0 1 1 1 1 Family of unknown function (DUF5631) Cytochrom_C1 PF02167.15 CBZ26662.1 - 0.038 13.7 0.2 0.071 12.8 0.2 1.4 1 0 0 1 1 1 0 Cytochrome C1 family Zn-ribbon_8 PF09723.10 CBZ26662.1 - 0.55 10.4 5.9 1.5 9.0 5.9 1.7 1 0 0 1 1 1 0 Zinc ribbon domain Pkinase PF00069.25 CBZ26663.1 - 6.6e-48 163.4 0.0 1e-30 107.0 0.0 3.2 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ26663.1 - 1.7e-29 102.9 0.0 3.6e-29 101.8 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CBZ26663.1 - 0.00034 19.5 0.0 0.00034 19.5 0.0 2.3 3 0 0 3 3 3 1 Fungal protein kinase Kinase-like PF14531.6 CBZ26663.1 - 0.058 12.7 0.0 0.1 11.9 0.0 1.2 1 0 0 1 1 1 0 Kinase-like ARD PF03079.14 CBZ26664.1 - 7.5e-37 126.9 0.0 2.3e-36 125.4 0.0 1.7 2 0 0 2 2 2 1 ARD/ARD' family DUF953 PF06110.11 CBZ26664.1 - 5.7e-16 58.2 0.0 9.5e-16 57.5 0.0 1.3 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF953) Cupin_2 PF07883.11 CBZ26664.1 - 4e-09 36.1 0.0 7.4e-09 35.2 0.0 1.4 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.19 CBZ26664.1 - 6.5e-06 26.1 0.2 1.5e-05 24.9 0.2 1.8 1 1 0 1 1 1 1 AraC-like ligand binding domain Cupin_1 PF00190.22 CBZ26664.1 - 0.03 13.9 0.0 0.055 13.1 0.0 1.3 1 0 0 1 1 1 0 Cupin Rap1a PF18602.1 CBZ26664.1 - 0.14 12.5 0.0 0.29 11.5 0.0 1.5 1 0 0 1 1 1 0 Rap1a immunity proteins NiFe-hyd_HybE PF11939.8 CBZ26666.1 - 0.02 14.8 0.3 0.2 11.6 0.0 2.4 2 0 0 2 2 2 0 [NiFe]-hydrogenase assembly, chaperone, HybE Glutaredoxin PF00462.24 CBZ26668.1 - 1e-11 44.8 0.0 1.5e-11 44.3 0.0 1.3 1 0 0 1 1 1 1 Glutaredoxin Thioredoxin_3 PF13192.6 CBZ26668.1 - 0.048 13.7 0.0 0.066 13.3 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin domain SH3BGR PF04908.15 CBZ26668.1 - 0.081 13.1 0.0 0.1 12.8 0.0 1.2 1 0 0 1 1 1 0 SH3-binding, glutamic acid-rich protein GST_N_3 PF13417.6 CBZ26668.1 - 0.086 13.3 0.0 0.11 12.9 0.0 1.2 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain BetaGal_dom4_5 PF13364.6 CBZ26668.1 - 0.11 13.1 0.0 0.14 12.7 0.0 1.2 1 0 0 1 1 1 0 Beta-galactosidase jelly roll domain zf-RING_2 PF13639.6 CBZ26676.1 - 0.00098 19.4 3.1 0.00098 19.4 3.1 2.0 2 0 0 2 2 2 1 Ring finger domain zf-rbx1 PF12678.7 CBZ26676.1 - 0.0037 17.5 11.7 0.0094 16.2 11.7 1.8 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 CBZ26676.1 - 0.0046 16.8 2.2 0.013 15.4 2.2 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 CBZ26676.1 - 0.0054 16.3 7.7 0.015 14.9 7.7 1.8 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-RING_5 PF14634.6 CBZ26676.1 - 3.9 7.5 12.9 4.5 7.3 8.8 2.8 1 1 1 2 2 2 0 zinc-RING finger domain AAA PF00004.29 CBZ26677.1 - 0.0052 17.2 0.0 0.011 16.1 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) T2SSE PF00437.20 CBZ26677.1 - 0.021 13.9 0.0 0.041 12.9 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein TetR_C_7 PF14246.6 CBZ26677.1 - 0.041 13.9 0.7 0.12 12.4 0.2 2.1 2 0 0 2 2 2 0 AefR-like transcriptional repressor, C-terminal domain AAA_22 PF13401.6 CBZ26677.1 - 0.043 14.1 0.3 0.18 12.0 0.0 2.2 2 0 0 2 2 2 0 AAA domain MORN PF02493.20 CBZ26678.1 - 1.2e-11 43.7 14.7 0.00042 20.0 1.1 4.7 4 0 0 4 4 4 3 MORN repeat PI3_PI4_kinase PF00454.27 CBZ26680.1 - 1.1e-46 159.7 0.0 2.2e-46 158.7 0.0 1.5 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FAT PF02259.23 CBZ26680.1 - 2.8e-30 105.7 2.4 5.4e-30 104.8 2.4 1.5 1 0 0 1 1 1 1 FAT domain FATC PF02260.20 CBZ26680.1 - 4.3e-09 36.0 0.0 1.4e-08 34.4 0.0 2.0 1 0 0 1 1 1 1 FATC domain TFCD_C PF12612.8 CBZ26680.1 - 0.00013 21.9 1.7 0.00068 19.5 0.1 3.2 3 0 0 3 3 3 1 Tubulin folding cofactor D C terminal HEAT PF02985.22 CBZ26680.1 - 0.00025 21.0 0.4 8.5 6.9 0.0 6.4 7 0 0 7 7 7 1 HEAT repeat TIP120 PF08623.10 CBZ26680.1 - 0.15 11.8 0.4 31 4.3 0.0 3.1 2 1 0 2 2 2 0 TATA-binding protein interacting (TIP20) DnaJ PF00226.31 CBZ26681.1 - 6.1e-18 64.7 2.3 6.7e-18 64.6 0.2 2.2 2 0 0 2 2 2 1 DnaJ domain Myb_DNA-binding PF00249.31 CBZ26681.1 - 0.00029 20.9 10.7 0.0027 17.9 0.3 3.8 4 0 0 4 4 4 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 CBZ26681.1 - 0.00086 19.5 3.3 0.055 13.7 0.5 3.2 3 0 0 3 3 3 2 Myb-like DNA-binding domain V_ATPase_I PF01496.19 CBZ26681.1 - 2 6.2 6.5 2.8 5.7 6.5 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family YIF1 PF03878.15 CBZ26682.1 - 1.2e-44 152.6 0.0 2e-44 151.9 0.0 1.2 1 1 0 1 1 1 1 YIF1 Yip1 PF04893.17 CBZ26682.1 - 0.0019 18.0 19.0 0.0019 17.9 17.9 1.5 1 1 0 1 1 1 1 Yip1 domain PRP38 PF03371.15 CBZ26683.1 - 3.6e-11 43.2 0.0 7.6e-11 42.2 0.0 1.5 2 0 0 2 2 2 1 PRP38 family CDP-OH_P_transf PF01066.21 CBZ26684.1 - 5.7 7.8 7.4 8.6 7.2 0.7 3.0 3 0 0 3 3 3 0 CDP-alcohol phosphatidyltransferase Esterase PF00756.20 CBZ26685.1 - 1.1e-14 54.7 0.1 1.1e-13 51.4 0.1 2.1 1 1 0 1 1 1 1 Putative esterase Peptidase_C2 PF00648.21 CBZ26687.1 - 1e-59 202.0 0.0 1.5e-59 201.5 0.0 1.2 1 0 0 1 1 1 1 Calpain family cysteine protease DUF1935 PF09149.10 CBZ26687.1 - 4.2e-34 117.0 0.1 8.3e-34 116.1 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1935) Calpain_III PF01067.22 CBZ26687.1 - 0.00018 21.8 0.0 0.00059 20.1 0.0 1.8 2 0 0 2 2 2 1 Calpain large subunit, domain III Sacchrp_dh_NADP PF03435.18 CBZ26687.1 - 0.023 14.9 0.0 0.048 13.9 0.0 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain FmiP_Thoc5 PF09766.9 CBZ26687.1 - 0.099 11.9 0.5 0.17 11.1 0.5 1.3 1 0 0 1 1 1 0 Fms-interacting protein/Thoc5 Peptidase_C2 PF00648.21 CBZ26688.1 - 1e-44 152.8 0.2 1.5e-44 152.2 0.2 1.2 1 0 0 1 1 1 1 Calpain family cysteine protease DUF1935 PF09149.10 CBZ26688.1 - 1.8e-22 79.6 0.1 4e-22 78.5 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1935) Calpain_III PF01067.22 CBZ26688.1 - 0.00016 21.9 0.0 0.00034 20.9 0.0 1.5 1 0 0 1 1 1 1 Calpain large subunit, domain III Peptidase_C2 PF00648.21 CBZ26689.1 - 3.7e-55 187.1 0.0 7.5e-55 186.0 0.0 1.5 2 0 0 2 2 2 1 Calpain family cysteine protease DUF1935 PF09149.10 CBZ26689.1 - 1.7e-33 115.1 0.2 3.6e-33 114.0 0.2 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1935) Peptidase_C2 PF00648.21 CBZ26690.1 - 3.6e-46 157.6 0.0 4.9e-46 157.1 0.0 1.1 1 0 0 1 1 1 1 Calpain family cysteine protease DUF1935 PF09149.10 CBZ26690.1 - 1.5e-24 86.3 0.0 3e-24 85.4 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1935) Peptidase_C2 PF00648.21 CBZ26691.1 - 1.1e-28 100.2 0.0 1.9e-28 99.3 0.0 1.4 1 0 0 1 1 1 1 Calpain family cysteine protease DUF1935 PF09149.10 CBZ26692.1 - 1e-23 83.6 0.0 1.3e-23 83.4 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1935) DUF1935 PF09149.10 CBZ26693.1 - 2.1e-27 95.5 0.0 2.7e-27 95.2 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1935) Raptor_N PF14538.6 CBZ26694.1 - 2.2e-09 37.4 0.0 4.5e-09 36.4 0.0 1.5 1 0 0 1 1 1 1 Raptor N-terminal CASPase like domain DUF1935 PF09149.10 CBZ26695.1 - 1.2e-28 99.5 0.0 2.3e-28 98.6 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1935) DUF4744 PF15918.5 CBZ26695.1 - 0.1 13.4 0.2 0.24 12.3 0.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4744) DUF1935 PF09149.10 CBZ26696.1 - 0.0034 17.7 0.0 3.8 8.0 0.0 2.5 2 0 0 2 2 2 2 Domain of unknown function (DUF1935) DUF1935 PF09149.10 CBZ26697.1 - 3.3e-07 30.6 0.0 5.1e-07 30.0 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1935) DUF1935 PF09149.10 CBZ26698.1 - 2.4e-30 104.9 0.1 3.1e-30 104.6 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1935) NAP PF00956.18 CBZ26699.1 - 2.6e-13 49.8 2.7 1.5e-08 34.2 0.1 2.1 1 1 1 2 2 2 2 Nucleosome assembly protein (NAP) DUF1935 PF09149.10 CBZ26700.1 - 2.4e-35 121.0 0.2 2.9e-35 120.8 0.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1935) DUF1935 PF09149.10 CBZ26701.1 - 7.9e-39 132.2 0.2 9.3e-39 132.0 0.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1935) TraS PF10624.9 CBZ26701.1 - 0.028 14.3 0.0 0.037 14.0 0.0 1.2 1 0 0 1 1 1 0 Plasmid conjugative transfer entry exclusion protein TraS Thioredoxin_8 PF13905.6 CBZ26702.1 - 0.0009 19.5 0.0 0.0021 18.3 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin-like LPD39 PF18858.1 CBZ26702.1 - 0.08 13.0 0.1 0.13 12.3 0.1 1.3 1 0 0 1 1 1 0 Large polyvalent protein associated domain 39 Pkinase PF00069.25 CBZ26703.1 - 8.6e-33 113.8 0.0 1.2e-32 113.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ26703.1 - 1.2e-17 64.1 0.0 1.9e-17 63.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CBZ26703.1 - 0.0092 15.3 0.0 0.029 13.7 0.0 1.7 1 1 0 1 1 1 1 Kinase-like Adaptin_N PF01602.20 CBZ26705.1 - 4.1e-63 213.7 6.5 5.4e-63 213.3 6.5 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Coatomer_b_Cpla PF14806.6 CBZ26705.1 - 8.2e-47 158.4 0.0 1.8e-46 157.3 0.0 1.6 1 0 0 1 1 1 1 Coatomer beta subunit appendage platform Coatamer_beta_C PF07718.12 CBZ26705.1 - 2.3e-42 144.2 0.0 5.4e-42 143.0 0.0 1.7 1 0 0 1 1 1 1 Coatomer beta C-terminal region HEAT PF02985.22 CBZ26705.1 - 2.5e-06 27.3 2.6 0.67 10.4 0.0 5.5 6 0 0 6 6 6 2 HEAT repeat HEAT_2 PF13646.6 CBZ26705.1 - 4.6e-06 26.9 5.6 0.37 11.2 0.0 5.2 7 1 0 7 7 7 3 HEAT repeats Cnd1 PF12717.7 CBZ26705.1 - 5.5e-05 23.3 4.7 0.00048 20.2 0.1 3.4 3 1 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 DUF5471 PF17565.2 CBZ26705.1 - 0.015 15.5 0.1 0.043 14.1 0.1 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5471) DUF4147 PF13660.6 CBZ26705.1 - 0.08 12.5 0.6 2 7.9 0.0 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4147) Coatomer_g_Cpla PF16381.5 CBZ26705.1 - 0.19 11.9 0.6 14 5.8 0.1 3.5 3 1 0 3 3 3 0 Coatomer subunit gamma-1 C-terminal appendage platform HEAT_EZ PF13513.6 CBZ26705.1 - 0.86 10.2 3.4 62 4.2 0.0 4.6 6 0 0 6 6 6 0 HEAT-like repeat RNase_PH PF01138.21 CBZ26706.1 - 0.078 13.5 0.1 0.37 11.3 0.0 2.1 2 1 0 2 2 2 0 3' exoribonuclease family, domain 1 PUF PF00806.19 CBZ26707.1 - 2e-17 61.8 0.1 0.0023 17.5 0.0 4.5 4 0 0 4 4 4 4 Pumilio-family RNA binding repeat ANAPC4_WD40 PF12894.7 CBZ26708.1 - 0.092 13.1 0.0 0.97 9.8 0.0 2.5 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain Tropomyosin_1 PF12718.7 CBZ26709.1 - 0.028 14.6 10.6 0.91 9.7 0.5 3.2 3 0 0 3 3 3 0 Tropomyosin like BRE1 PF08647.11 CBZ26709.1 - 0.071 13.2 7.5 0.24 11.5 0.2 2.9 3 0 0 3 3 3 0 BRE1 E3 ubiquitin ligase DUF4376 PF14301.6 CBZ26709.1 - 0.14 12.5 0.2 0.14 12.5 0.2 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4376) Striatin PF08232.12 CBZ26709.1 - 0.25 11.9 12.5 0.1 13.2 1.1 2.9 2 1 1 3 3 3 0 Striatin family DivIC PF04977.15 CBZ26709.1 - 0.83 9.5 12.7 0.12 12.1 0.4 3.2 3 0 0 3 3 3 0 Septum formation initiator Spc24 PF08286.11 CBZ26709.1 - 3 8.1 10.5 3.9 7.8 0.3 3.4 3 1 0 3 3 3 0 Spc24 subunit of Ndc80 Trimer_CC PF08954.11 CBZ26709.1 - 5.3 6.7 28.0 0.1 12.2 1.8 5.0 5 0 0 5 5 5 0 Trimerisation motif ADIP PF11559.8 CBZ26709.1 - 5.4 7.1 21.9 3 7.9 2.5 3.8 4 0 0 4 4 4 0 Afadin- and alpha -actinin-Binding CENP-F_leu_zip PF10473.9 CBZ26709.1 - 6.6 6.8 13.4 0.28 11.2 0.6 3.2 3 0 0 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Arm PF00514.23 CBZ26710.1 - 7.1e-34 114.8 20.3 8.1e-07 28.9 0.0 8.9 9 0 0 9 9 9 7 Armadillo/beta-catenin-like repeat HEAT PF02985.22 CBZ26710.1 - 4.5e-18 63.8 10.1 0.029 14.6 0.1 8.0 8 0 0 8 8 8 4 HEAT repeat HEAT_2 PF13646.6 CBZ26710.1 - 7.5e-17 61.5 13.9 0.00021 21.6 0.1 5.3 2 2 4 6 6 6 6 HEAT repeats HEAT_EZ PF13513.6 CBZ26710.1 - 2.4e-15 56.7 16.7 0.014 15.9 0.4 6.4 6 1 1 7 7 7 5 HEAT-like repeat Cnd1 PF12717.7 CBZ26710.1 - 9.5e-13 48.5 0.1 0.0015 18.6 0.0 3.7 2 1 2 4 4 4 3 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.20 CBZ26710.1 - 1.3e-10 40.5 1.2 2.6e-08 32.9 1.3 3.1 2 1 0 2 2 2 1 Adaptin N terminal region DNA_alkylation PF08713.11 CBZ26710.1 - 7.5e-09 35.6 0.1 0.0079 15.9 0.0 4.1 2 1 2 4 4 4 3 DNA alkylation repair enzyme CLASP_N PF12348.8 CBZ26710.1 - 3.3e-05 23.6 0.6 0.29 10.7 0.0 3.0 1 1 1 2 2 2 2 CLASP N terminal V-ATPase_H_C PF11698.8 CBZ26710.1 - 0.00035 20.6 0.3 0.34 11.0 0.3 3.9 3 2 1 4 4 4 2 V-ATPase subunit H Mo25 PF08569.11 CBZ26710.1 - 0.00054 19.4 0.1 0.23 10.8 0.1 2.4 1 1 0 2 2 2 2 Mo25-like CHASE6_C PF17150.4 CBZ26710.1 - 0.0007 20.2 3.3 14 6.5 0.0 5.5 5 1 0 6 6 6 0 C-terminal domain of two-partite extracellular sensor domain RICTOR_N PF14664.6 CBZ26710.1 - 0.0009 18.3 0.6 0.045 12.7 0.2 3.0 1 1 1 2 2 2 1 Rapamycin-insensitive companion of mTOR, N-term HEAT_PBS PF03130.16 CBZ26710.1 - 0.003 18.1 13.1 0.82 10.5 2.2 6.0 5 1 0 5 5 5 1 PBS lyase HEAT-like repeat Proteasom_PSMB PF10508.9 CBZ26710.1 - 0.0043 15.6 3.0 0.4 9.1 0.6 2.8 1 1 1 2 2 2 2 Proteasome non-ATPase 26S subunit HEAT_UF PF18817.1 CBZ26710.1 - 0.0057 16.9 0.0 0.31 11.4 0.0 3.5 3 0 0 3 3 3 1 Repeat of uncharacterized protein PH0542 Vac14_Fab1_bd PF12755.7 CBZ26710.1 - 0.028 15.0 0.1 0.69 10.6 0.0 3.1 1 1 3 4 4 4 0 Vacuolar 14 Fab1-binding region DUF3361 PF11841.8 CBZ26710.1 - 0.051 13.5 0.4 4.7 7.1 0.1 3.2 3 1 1 4 4 4 0 Domain of unknown function (DUF3361) SET PF00856.28 CBZ26713.1 - 0.00036 21.0 0.0 0.0014 19.0 0.0 1.8 1 1 0 1 1 1 1 SET domain ubiquitin PF00240.23 CBZ26715.1 - 4.2e-06 26.4 0.0 0.0021 17.8 0.0 2.9 3 0 0 3 3 3 2 Ubiquitin family CENP-H PF05837.12 CBZ26715.1 - 0.3 11.5 4.1 0.55 10.7 4.1 1.4 1 0 0 1 1 1 0 Centromere protein H (CENP-H) Spc7 PF08317.11 CBZ26715.1 - 0.34 9.7 5.7 0.19 10.6 3.8 1.5 2 0 0 2 2 2 0 Spc7 kinetochore protein PUMA PF15826.5 CBZ26716.1 - 0.00049 20.3 1.3 0.0041 17.3 1.9 1.8 2 0 0 2 2 2 1 Bcl-2-binding component 3, p53 upregulated modulator of apoptosis C2 PF00168.30 CBZ26716.1 - 0.08 13.2 0.0 0.14 12.4 0.0 1.3 1 0 0 1 1 1 0 C2 domain Myotub-related PF06602.14 CBZ26718.1 - 1.3e-91 307.2 0.0 3.9e-91 305.6 0.0 1.8 1 1 0 1 1 1 1 Myotubularin-like phosphatase domain Y_phosphatase3 PF13350.6 CBZ26718.1 - 0.005 16.9 0.0 0.01 15.8 0.0 1.5 1 0 0 1 1 1 1 Tyrosine phosphatase family FYVE_2 PF02318.16 CBZ26718.1 - 0.0084 16.3 3.9 0.022 15.0 3.9 1.7 1 0 0 1 1 1 1 FYVE-type zinc finger FYVE PF01363.21 CBZ26718.1 - 0.33 11.1 11.6 1 9.6 11.6 1.8 1 0 0 1 1 1 0 FYVE zinc finger C1_4 PF07975.12 CBZ26718.1 - 1.7 8.9 12.0 7.4 6.9 12.0 2.1 1 0 0 1 1 1 0 TFIIH C1-like domain HEAT PF02985.22 CBZ26719.1 - 0.0065 16.6 0.1 1.2 9.6 0.0 3.4 2 1 0 2 2 2 1 HEAT repeat MMS19_C PF12460.8 CBZ26719.1 - 0.069 12.3 1.7 0.078 12.1 0.1 2.0 3 0 0 3 3 3 0 RNAPII transcription regulator C-terminal DUF1834 PF08873.11 CBZ26719.1 - 0.13 12.0 0.2 0.79 9.4 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1834) DNA_alkylation PF08713.11 CBZ26720.1 - 0.063 13.0 1.4 0.12 12.1 1.4 1.4 1 0 0 1 1 1 0 DNA alkylation repair enzyme PolyA_pol_RNAbd PF12627.7 CBZ26721.1 - 0.094 12.5 0.0 1.5 8.6 0.0 2.7 2 0 0 2 2 2 0 Probable RNA and SrmB- binding site of polymerase A RCDG1 PF15725.5 CBZ26721.1 - 0.84 10.1 8.7 0.79 10.2 3.0 3.7 2 0 0 2 2 2 0 Renal cancer differentiation gene 1 protein DUF4456 PF14644.6 CBZ26722.1 - 1.3e-11 44.7 0.0 1.3e-11 44.7 0.0 4.2 5 0 0 5 5 5 1 Domain of unknown function (DUF4456) DUF4455 PF14643.6 CBZ26722.1 - 2.6e-05 23.1 0.9 2.6e-05 23.1 0.9 3.9 3 1 0 3 3 3 1 Domain of unknown function (DUF4455) Phage_GP20 PF06810.11 CBZ26722.1 - 0.05 13.4 1.3 0.21 11.4 1.3 2.1 1 0 0 1 1 1 0 Phage minor structural protein GP20 AAA PF00004.29 CBZ26723.1 - 8.6e-28 97.4 0.0 3.6e-26 92.1 0.0 2.5 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 CBZ26723.1 - 0.00036 20.9 7.5 0.0038 17.6 0.1 4.1 3 2 0 4 4 4 1 AAA ATPase domain AAA_22 PF13401.6 CBZ26723.1 - 0.00048 20.4 0.0 0.022 15.0 0.0 2.8 1 1 0 1 1 1 1 AAA domain ABC_tran PF00005.27 CBZ26723.1 - 0.017 15.6 0.0 0.034 14.7 0.0 1.5 1 0 0 1 1 1 0 ABC transporter AAA_29 PF13555.6 CBZ26723.1 - 0.05 13.4 0.0 0.12 12.1 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain NACHT PF05729.12 CBZ26723.1 - 0.063 13.2 1.8 2.3 8.1 0.1 3.3 2 1 0 2 2 2 0 NACHT domain TIP49 PF06068.13 CBZ26723.1 - 0.069 12.3 0.0 0.12 11.5 0.0 1.4 1 0 0 1 1 1 0 TIP49 P-loop domain IstB_IS21 PF01695.17 CBZ26723.1 - 0.074 12.8 0.0 0.15 11.8 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_7 PF12775.7 CBZ26723.1 - 0.13 11.8 0.0 0.25 10.8 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_18 PF13238.6 CBZ26723.1 - 0.15 12.6 0.0 0.39 11.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 CBZ26723.1 - 0.28 11.7 0.0 0.69 10.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 CBZ26723.1 - 0.67 9.5 5.9 3.7 7.1 0.2 3.2 3 1 1 4 4 4 0 AAA domain Zeta_toxin PF06414.12 CBZ26723.1 - 0.72 9.1 2.6 6.2 6.0 0.0 2.9 3 0 0 3 3 3 0 Zeta toxin RabGAP-TBC PF00566.18 CBZ26725.1 - 3.6e-14 53.0 0.1 6.9e-14 52.0 0.1 1.4 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Troponin-I_N PF11636.8 CBZ26725.1 - 4.1 7.4 8.1 0.93 9.5 0.2 2.5 2 0 0 2 2 2 0 Troponin I residues 1-32 SGS PF05002.15 CBZ26726.1 - 4.1e-32 110.1 0.5 6.7e-32 109.5 0.5 1.3 1 0 0 1 1 1 1 SGS domain CS PF04969.16 CBZ26726.1 - 2.4e-05 25.3 0.5 5.8e-05 24.0 0.1 1.8 3 0 0 3 3 3 1 CS domain Ribosomal_S17 PF00366.20 CBZ26727.1 - 2.7e-23 81.8 0.3 5.1e-23 81.0 0.3 1.5 1 0 0 1 1 1 1 Ribosomal protein S17 Ribosomal_S17_N PF16205.5 CBZ26727.1 - 1.1e-21 77.0 1.5 1.1e-21 77.0 0.1 1.7 2 0 0 2 2 2 1 Ribosomal_S17 N-terminal DnaB_2 PF07261.11 CBZ26728.1 - 0.13 12.1 0.0 0.29 10.9 0.0 1.5 1 0 0 1 1 1 0 Replication initiation and membrane attachment Brix PF04427.18 CBZ26729.1 - 5.2e-33 114.8 0.1 7.1e-33 114.3 0.1 1.2 1 0 0 1 1 1 1 Brix domain Peptidase_C50 PF03568.17 CBZ26730.1 - 2e-37 129.3 0.4 6.6e-32 111.1 0.5 2.9 2 1 0 2 2 2 2 Peptidase family C50 CHAT PF12770.7 CBZ26730.1 - 1.7e-10 40.8 0.8 1.9e-05 24.3 0.1 2.6 2 0 0 2 2 2 2 CHAT domain SNAP PF14938.6 CBZ26731.1 - 3.7e-56 190.6 14.5 4.2e-56 190.4 14.5 1.0 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP TPR_12 PF13424.6 CBZ26731.1 - 2.7e-07 30.8 9.2 6.8e-06 26.3 1.5 3.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.6 CBZ26731.1 - 0.0061 16.5 1.2 6.7 7.0 0.0 4.1 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_MalT PF17874.1 CBZ26731.1 - 0.051 13.0 2.7 0.082 12.3 2.7 1.4 1 1 0 1 1 1 0 MalT-like TPR region DUF3741 PF12552.8 CBZ26731.1 - 0.08 12.9 0.9 0.61 10.1 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3741) DUF1033 PF06279.11 CBZ26731.1 - 0.081 13.1 0.2 0.081 13.1 0.2 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF1033) TPR_6 PF13174.6 CBZ26731.1 - 0.18 12.5 15.5 25 5.8 3.4 5.7 3 3 2 5 5 5 0 Tetratricopeptide repeat TPR_8 PF13181.6 CBZ26731.1 - 0.21 11.9 10.6 3.2 8.2 0.3 4.8 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.28 CBZ26731.1 - 0.71 9.8 13.7 0.42 10.5 0.4 4.5 4 1 1 5 5 5 0 Tetratricopeptide repeat MIT PF04212.18 CBZ26731.1 - 4.3 7.5 13.6 5.3 7.2 0.6 4.5 5 0 0 5 5 5 0 MIT (microtubule interacting and transport) domain tRNA_U5-meth_tr PF05958.11 CBZ26733.1 - 1.4e-18 67.1 0.0 1.6e-17 63.6 0.0 2.2 1 1 0 1 1 1 1 tRNA (Uracil-5-)-methyltransferase Methyltransf_31 PF13847.6 CBZ26733.1 - 1.2e-09 38.1 0.0 2.2e-09 37.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CBZ26733.1 - 9.8e-09 35.8 0.0 2.4e-08 34.6 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.15 CBZ26733.1 - 2.7e-06 27.1 0.0 5.2e-06 26.2 0.0 1.4 1 0 0 1 1 1 1 Conserved hypothetical protein 95 PCMT PF01135.19 CBZ26733.1 - 5.9e-05 22.9 0.0 0.00012 21.9 0.0 1.4 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MTS PF05175.14 CBZ26733.1 - 6.4e-05 22.6 0.0 0.00013 21.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_11 PF08241.12 CBZ26733.1 - 0.00011 22.8 0.0 0.00028 21.5 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 CBZ26733.1 - 0.00049 19.5 0.2 0.0012 18.2 0.0 1.7 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_15 PF09445.10 CBZ26733.1 - 0.00063 19.4 0.0 0.001 18.6 0.0 1.3 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltransf_4 PF02390.17 CBZ26733.1 - 0.003 17.0 0.0 0.0064 16.0 0.0 1.5 1 0 0 1 1 1 1 Putative methyltransferase PrmA PF06325.13 CBZ26733.1 - 0.0072 15.8 0.1 0.012 15.0 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) DOT1 PF08123.13 CBZ26733.1 - 0.011 15.2 0.0 0.022 14.3 0.0 1.4 1 0 0 1 1 1 0 Histone methylation protein DOT1 Methyltransf_32 PF13679.6 CBZ26733.1 - 0.015 15.3 0.0 0.033 14.2 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain TPMT PF05724.11 CBZ26733.1 - 0.027 14.1 0.0 0.1 12.3 0.0 1.8 2 0 0 2 2 2 0 Thiopurine S-methyltransferase (TPMT) Methyltransf_18 PF12847.7 CBZ26733.1 - 0.046 13.7 0.0 0.085 12.8 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_23 PF13489.6 CBZ26733.1 - 0.13 12.0 0.0 0.28 11.0 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain RNA_ligase PF09414.10 CBZ26735.1 - 1.5e-23 83.8 0.0 2.2e-23 83.3 0.0 1.2 1 0 0 1 1 1 1 RNA ligase T4_Rnl2_C PF18043.1 CBZ26735.1 - 1.8e-08 34.4 0.0 5.3e-08 32.9 0.0 1.8 1 0 0 1 1 1 1 T4 RNA ligase 2 C-terminal Peptidase_M3_N PF08439.10 CBZ26735.1 - 0.13 12.5 1.1 0.61 10.4 0.0 2.8 3 0 0 3 3 3 0 Oligopeptidase F Peptidase_M20 PF01546.28 CBZ26737.1 - 2.6e-30 105.7 0.1 3.4e-30 105.3 0.1 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 CBZ26737.1 - 8.8e-10 38.5 0.0 2e-09 37.4 0.0 1.6 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 CBZ26737.1 - 0.095 12.4 0.0 0.13 11.9 0.0 1.2 1 0 0 1 1 1 0 Peptidase family M28 Thi4 PF01946.17 CBZ26737.1 - 0.099 11.9 0.5 2.5 7.3 0.0 2.5 2 1 0 3 3 3 0 Thi4 family Peptidase_M20 PF01546.28 CBZ26738.1 - 2.3e-31 109.1 0.1 3e-31 108.7 0.1 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 CBZ26738.1 - 1.1e-09 38.1 0.0 3.1e-09 36.7 0.0 1.7 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 CBZ26738.1 - 0.11 12.1 0.0 0.16 11.7 0.0 1.2 1 0 0 1 1 1 0 Peptidase family M28 Peptidase_M20 PF01546.28 CBZ26739.1 - 2.5e-31 109.0 0.1 3.2e-31 108.6 0.1 1.1 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 CBZ26739.1 - 1.2e-09 38.1 0.0 3.1e-09 36.7 0.0 1.7 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 CBZ26739.1 - 0.099 12.3 0.0 0.15 11.7 0.0 1.3 1 0 0 1 1 1 0 Peptidase family M28 PPR_2 PF13041.6 CBZ26740.1 - 1.4e-15 57.2 2.9 3.2e-05 24.0 0.0 5.5 5 0 0 5 5 5 3 PPR repeat family PPR_3 PF13812.6 CBZ26740.1 - 3.3e-14 52.7 0.1 3.6e-05 23.8 0.0 4.9 4 1 0 5 5 5 3 Pentatricopeptide repeat domain PPR_long PF17177.4 CBZ26740.1 - 2.3e-12 46.8 0.8 0.00052 19.4 0.1 3.5 2 1 1 3 3 3 3 Pentacotripeptide-repeat region of PRORP PPR_1 PF12854.7 CBZ26740.1 - 4.5e-05 23.1 0.1 0.59 9.9 0.0 4.9 5 0 0 5 5 5 1 PPR repeat PPR PF01535.20 CBZ26740.1 - 0.00047 20.2 8.2 1.8 9.0 0.0 5.8 7 0 0 7 7 7 2 PPR repeat Pkr1 PF08636.10 CBZ26741.1 - 3.2e-05 24.0 10.6 4.1e-05 23.6 10.6 1.1 1 0 0 1 1 1 1 ER protein Pkr1 ANAPC4_WD40 PF12894.7 CBZ26742.1 - 0.0043 17.3 0.0 0.1 12.9 0.0 2.6 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain OprB PF04966.12 CBZ26743.1 - 0.19 11.1 0.0 0.27 10.6 0.0 1.2 1 0 0 1 1 1 0 Carbohydrate-selective porin, OprB family CHORD PF04968.12 CBZ26744.1 - 5.3e-39 132.8 33.7 1.2e-19 70.8 12.2 2.3 2 0 0 2 2 2 2 CHORD Tetraspanin PF00335.20 CBZ26744.1 - 0.62 9.7 4.5 0.55 9.9 3.2 1.6 1 1 0 1 1 1 0 Tetraspanin family CENP-T_C PF15511.6 CBZ26745.1 - 6.3e-06 26.3 0.0 8.7e-06 25.8 0.0 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CBFD_NFYB_HMF PF00808.23 CBZ26745.1 - 1.3e-05 25.4 0.2 1.7e-05 25.0 0.2 1.1 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.13 CBZ26745.1 - 0.0004 20.3 0.0 0.00055 19.9 0.0 1.2 1 0 0 1 1 1 1 Bromodomain associated Histone PF00125.24 CBZ26745.1 - 0.0006 20.2 0.4 0.00075 19.9 0.4 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TAF PF02969.17 CBZ26745.1 - 0.00098 19.2 0.2 0.0014 18.8 0.2 1.2 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) TFIID-31kDa PF02291.15 CBZ26745.1 - 0.011 15.8 0.0 0.013 15.6 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Sigma70_r4 PF04545.16 CBZ26745.1 - 0.078 12.5 0.5 0.15 11.6 0.5 1.5 1 0 0 1 1 1 0 Sigma-70, region 4 Peptidase_S8 PF00082.22 CBZ26745.1 - 0.09 12.0 0.0 0.097 11.9 0.0 1.0 1 0 0 1 1 1 0 Subtilase family PCP_red PF08369.10 CBZ26745.1 - 0.38 11.0 6.7 0.85 9.9 0.8 2.5 2 1 1 3 3 3 0 Proto-chlorophyllide reductase 57 kD subunit Methyltransf_12 PF08242.12 CBZ26746.1 - 5.6e-15 55.9 0.0 5.5e-13 49.5 0.1 2.5 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 CBZ26746.1 - 1.9e-13 50.9 0.0 2.5e-06 28.1 0.0 3.1 3 0 0 3 3 3 2 Methyltransferase domain Methyltransf_23 PF13489.6 CBZ26746.1 - 6.9e-13 48.8 0.0 1e-12 48.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CBZ26746.1 - 2e-12 47.2 0.0 3.8e-05 23.5 0.0 2.3 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_11 PF08241.12 CBZ26746.1 - 1.2e-11 45.1 0.2 3.1e-09 37.4 0.1 2.6 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_24 PF13578.6 CBZ26746.1 - 0.00082 20.4 0.0 0.002 19.1 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain NodS PF05401.11 CBZ26746.1 - 0.0012 18.4 0.0 0.0095 15.6 0.0 2.0 2 0 0 2 2 2 1 Nodulation protein S (NodS) zf-rbx1 PF12678.7 CBZ26747.1 - 1.4e-24 86.1 15.7 1.9e-24 85.7 15.7 1.2 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 CBZ26747.1 - 3.5e-17 62.2 11.6 4.2e-17 62.0 11.6 1.1 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_2 PF13639.6 CBZ26747.1 - 8.3e-06 26.0 17.7 0.00034 20.9 17.7 2.3 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 CBZ26747.1 - 0.001 18.9 15.8 0.066 13.1 15.8 2.3 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CBZ26747.1 - 0.0073 16.1 14.3 0.091 12.7 14.3 2.2 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CBZ26747.1 - 0.054 13.5 8.7 0.1 12.7 8.7 1.5 1 1 0 1 1 1 0 RING-type zinc-finger Zn_ribbon_17 PF17120.5 CBZ26747.1 - 0.33 10.6 16.5 0.07 12.8 4.6 2.2 1 1 1 2 2 2 0 Zinc-ribbon, C4HC2 type zf-RING_11 PF17123.5 CBZ26747.1 - 1.5 8.7 15.2 55 3.6 15.2 2.4 1 1 0 1 1 1 0 RING-like zinc finger zf-RING_5 PF14634.6 CBZ26747.1 - 6.6 6.8 14.7 65 3.6 14.8 2.3 1 1 0 1 1 1 0 zinc-RING finger domain HBM PF16591.5 CBZ26749.1 - 0.00028 20.4 8.8 0.0073 15.8 0.1 2.7 1 1 0 2 2 2 2 Helical bimodular sensor domain DUF1664 PF07889.12 CBZ26749.1 - 0.00068 19.7 4.3 0.096 12.7 0.1 2.7 2 1 0 2 2 2 2 Protein of unknown function (DUF1664) Baculo_PEP_C PF04513.12 CBZ26749.1 - 0.0032 17.5 0.5 2 8.5 0.1 2.4 2 0 0 2 2 2 2 Baculovirus polyhedron envelope protein, PEP, C terminus DUF3450 PF11932.8 CBZ26749.1 - 0.017 14.5 7.8 1.5 8.1 2.2 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF3450) PHM7_cyt PF14703.6 CBZ26749.1 - 0.019 15.2 6.3 0.031 14.5 6.3 1.4 1 0 0 1 1 1 0 Cytosolic domain of 10TM putative phosphate transporter DASH_Duo1 PF08651.10 CBZ26749.1 - 0.031 14.0 2.0 0.46 10.3 0.4 2.6 2 0 0 2 2 2 0 DASH complex subunit Duo1 Translat_reg PF01818.17 CBZ26749.1 - 0.042 13.8 0.1 0.097 12.7 0.0 1.6 1 1 0 1 1 1 0 Bacteriophage translational regulator T3SS_basalb_I PF17001.5 CBZ26749.1 - 0.09 13.4 3.7 3.8 8.2 0.1 2.9 2 1 0 2 2 2 0 Type III secretion basal body protein I, YscI, HrpB, PscI DUF4047 PF13256.6 CBZ26749.1 - 0.098 12.9 2.7 2.9 8.1 0.1 3.1 1 1 2 3 3 3 0 Domain of unknown function (DUF4047) DUF948 PF06103.11 CBZ26749.1 - 0.17 12.2 5.0 5.5 7.3 1.2 3.0 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) PRKG1_interact PF15898.5 CBZ26749.1 - 0.55 11.2 11.7 0.4 11.6 5.0 2.7 3 0 0 3 3 3 0 cGMP-dependent protein kinase interacting domain DUF5344 PF17279.2 CBZ26749.1 - 0.56 10.8 6.5 3.7 8.2 0.2 3.8 3 2 1 4 4 4 0 Family of unknown function (DUF5344) DUF1043 PF06295.12 CBZ26749.1 - 0.6 10.1 5.7 0.98 9.4 0.9 2.9 3 1 0 3 3 3 0 Protein of unknown function (DUF1043) OmpH PF03938.14 CBZ26749.1 - 0.79 10.1 13.5 2.5 8.4 11.5 2.5 2 1 0 2 2 2 0 Outer membrane protein (OmpH-like) AAA_11 PF13086.6 CBZ26749.1 - 1.1 9.0 6.0 1.7 8.3 6.0 1.5 1 1 0 1 1 1 0 AAA domain DUF4407 PF14362.6 CBZ26749.1 - 1.6 8.0 9.4 3.4 7.0 9.3 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) FlaC_arch PF05377.11 CBZ26749.1 - 1.7 9.1 5.2 28 5.2 0.2 3.1 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) OmpH PF03938.14 CBZ26750.1 - 0.003 17.9 6.5 0.0056 17.0 2.1 2.1 2 0 0 2 2 2 1 Outer membrane protein (OmpH-like) HEPN_Apea PF18739.1 CBZ26750.1 - 0.0046 17.4 0.9 0.015 15.7 0.2 2.2 1 1 1 2 2 2 1 Apea-like HEPN Halogen_Hydrol PF10112.9 CBZ26750.1 - 0.009 16.0 3.9 0.039 14.0 0.7 2.3 2 1 0 2 2 2 1 5-bromo-4-chloroindolyl phosphate hydrolysis protein DUF3584 PF12128.8 CBZ26750.1 - 0.027 12.0 5.7 0.048 11.2 2.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) HEPN_Cthe2314 PF18730.1 CBZ26750.1 - 0.065 13.3 2.6 0.097 12.7 0.9 1.9 2 0 0 2 2 2 0 Cthe_2314-like HEPN FlaF PF07309.11 CBZ26750.1 - 0.094 12.7 0.9 0.41 10.7 0.0 2.1 2 0 0 2 2 2 0 Flagellar protein FlaF Goodbye PF17109.5 CBZ26750.1 - 0.095 13.2 2.7 6.1 7.3 0.5 2.8 2 1 0 3 3 3 0 fungal STAND N-terminal Goodbye domain TMPIT PF07851.13 CBZ26750.1 - 0.18 11.1 6.3 3.6 6.7 0.1 2.1 2 0 0 2 2 2 0 TMPIT-like protein V_ATPase_I PF01496.19 CBZ26750.1 - 0.3 8.9 4.5 0.65 7.9 0.2 2.0 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family TPR_21 PF09976.9 CBZ26750.1 - 0.44 10.2 5.2 0.41 10.3 1.3 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat-like domain PIN_8 PF18476.1 CBZ26750.1 - 0.88 9.4 8.8 1.6 8.5 4.3 2.4 1 1 0 2 2 2 0 PIN like domain DegS PF05384.11 CBZ26750.1 - 1.1 8.7 11.0 0.42 10.1 0.2 2.8 2 1 0 2 2 2 0 Sensor protein DegS Jnk-SapK_ap_N PF09744.9 CBZ26750.1 - 3 8.0 13.9 1.4 9.1 6.3 2.8 3 1 0 3 3 3 0 JNK_SAPK-associated protein-1 CIAPIN1 PF05093.13 CBZ26750.1 - 3.5 8.2 6.7 4.8 7.8 1.0 2.4 2 1 0 2 2 2 0 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis SNARE PF05739.19 CBZ26751.1 - 6.1e-08 32.5 1.5 1.8e-07 31.1 1.5 1.8 1 0 0 1 1 1 1 SNARE domain Syntaxin-6_N PF09177.11 CBZ26751.1 - 0.0033 17.9 1.3 0.047 14.2 0.1 2.3 2 0 0 2 2 2 1 Syntaxin 6, N-terminal Ada3 PF10198.9 CBZ26751.1 - 0.19 11.9 4.5 1.5 9.0 0.1 2.6 1 1 2 3 3 3 0 Histone acetyltransferases subunit 3 WD40 PF00400.32 CBZ26753.1 - 3.4e-20 72.0 9.4 6.2e-08 33.2 0.1 5.7 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBZ26753.1 - 0.00014 22.1 0.1 0.17 12.2 0.0 3.2 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 CBZ26753.1 - 0.00025 19.8 3.6 0.056 12.1 0.3 3.3 2 2 3 5 5 5 2 Nucleoporin Nup120/160 Tom22 PF04281.13 CBZ26753.1 - 0.17 11.6 0.0 0.29 10.9 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial import receptor subunit Tom22 Allexi_40kDa PF05549.11 CBZ26754.1 - 0.093 12.2 0.0 0.11 12.0 0.0 1.2 1 0 0 1 1 1 0 Allexivirus 40kDa protein MFS_1 PF07690.16 CBZ26755.1 - 2.5e-19 69.4 28.9 2.5e-19 69.4 28.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily PgaD PF13994.6 CBZ26756.1 - 0.023 14.8 0.3 0.023 14.8 0.3 1.7 2 0 0 2 2 2 0 PgaD-like protein DUF3043 PF11241.8 CBZ26756.1 - 0.23 11.5 0.1 0.23 11.5 0.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3043) DUF5090 PF17009.5 CBZ26756.1 - 3.1 7.7 5.5 1.4 8.8 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF5090) UPF0542 PF15086.6 CBZ26756.1 - 6.5 6.8 6.0 1.1 9.2 1.0 2.0 2 0 0 2 2 2 0 Uncharacterised protein family UPF0542 LapA_dom PF06305.11 CBZ26756.1 - 9.1 6.2 11.3 0.091 12.6 2.7 2.2 3 0 0 3 3 3 0 Lipopolysaccharide assembly protein A domain Peptidase_C2 PF00648.21 CBZ26759.1 - 1.9e-32 112.5 0.0 3.3e-32 111.7 0.0 1.3 1 0 0 1 1 1 1 Calpain family cysteine protease Calpain_III PF01067.22 CBZ26759.1 - 3.5e-30 105.1 0.0 3.4e-09 37.1 0.0 7.3 6 2 0 6 6 6 5 Calpain large subunit, domain III JHY PF15261.6 CBZ26759.1 - 0.19 12.4 1.3 0.61 10.8 1.3 1.8 1 0 0 1 1 1 0 Jhy protein Topoisom_bac PF01131.20 CBZ26760.1 - 1.3e-75 254.9 0.0 2.9e-75 253.8 0.0 1.5 1 1 0 1 1 1 1 DNA topoisomerase Toprim PF01751.22 CBZ26760.1 - 1.1e-14 54.5 0.0 2.8e-14 53.2 0.0 1.8 1 0 0 1 1 1 1 Toprim domain Toprim_4 PF13662.6 CBZ26760.1 - 0.013 16.0 0.1 0.071 13.6 0.0 2.3 2 0 0 2 2 2 0 Toprim domain FleQ PF06490.11 CBZ26760.1 - 0.064 13.6 0.0 0.16 12.3 0.0 1.6 1 0 0 1 1 1 0 Flagellar regulatory protein FleQ Pkinase PF00069.25 CBZ26761.1 - 7.2e-54 182.9 0.0 1.2e-53 182.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ26761.1 - 3e-31 108.7 0.0 4.9e-31 107.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Guanylate_cyc PF00211.20 CBZ26761.1 - 0.00043 20.0 0.0 0.0009 18.9 0.0 1.5 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain Kdo PF06293.14 CBZ26761.1 - 0.0012 18.2 0.1 0.0031 16.9 0.0 1.6 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 CBZ26761.1 - 0.025 13.9 0.0 0.079 12.3 0.0 1.7 2 0 0 2 2 2 0 Kinase-like Pkinase_fungal PF17667.1 CBZ26761.1 - 0.028 13.2 0.0 0.055 12.2 0.0 1.4 1 0 0 1 1 1 0 Fungal protein kinase APH PF01636.23 CBZ26761.1 - 0.088 12.7 0.4 2.6 7.9 0.0 2.4 2 0 0 2 2 2 0 Phosphotransferase enzyme family DUF4083 PF13314.6 CBZ26761.1 - 5.6 7.0 6.3 4.2 7.4 0.8 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4083) RPN6_N PF18055.1 CBZ26762.1 - 0.21 12.0 1.9 0.95 9.8 0.0 2.9 4 0 0 4 4 4 0 26S proteasome regulatory subunit RPN6 N-terminal domain Pkinase PF00069.25 CBZ26763.1 - 1.1e-36 126.5 0.0 1.8e-36 125.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ26763.1 - 1.1e-13 51.1 0.0 2.5e-12 46.6 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CBZ26763.1 - 0.052 12.9 0.1 0.2 10.9 0.1 1.8 1 1 0 1 1 1 0 Kinase-like LRR_4 PF12799.7 CBZ26764.1 - 1.7e-11 44.1 0.5 0.077 13.5 0.0 7.2 5 2 1 6 6 6 2 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 CBZ26764.1 - 1.3e-08 34.3 17.1 0.019 15.0 0.0 9.2 11 0 0 11 11 11 3 Leucine Rich repeat LRR_8 PF13855.6 CBZ26764.1 - 0.00033 20.3 12.4 4.3 7.2 0.1 7.2 7 2 0 7 7 7 3 Leucine rich repeat RE_SinI PF09570.10 CBZ26764.1 - 0.014 14.7 0.0 0.046 12.9 0.0 1.7 2 0 0 2 2 2 0 SinI restriction endonuclease Neurensin PF14927.6 CBZ26764.1 - 0.11 12.3 0.1 0.34 10.6 0.1 1.8 1 0 0 1 1 1 0 Neurensin LRR_1 PF00560.33 CBZ26764.1 - 0.65 10.8 10.6 1.3e+02 3.7 0.0 7.9 10 1 0 10 10 10 0 Leucine Rich Repeat PUF PF00806.19 CBZ26765.1 - 0.0061 16.2 5.2 7.8 6.4 0.0 5.3 6 1 1 7 7 7 2 Pumilio-family RNA binding repeat CHAT PF12770.7 CBZ26766.1 - 7.3e-50 170.0 0.3 1.4e-49 169.1 0.3 1.5 1 0 0 1 1 1 1 CHAT domain LRR_6 PF13516.6 CBZ26766.1 - 0.00043 20.1 4.4 2.5 8.4 0.0 3.7 3 0 0 3 3 3 2 Leucine Rich repeat TPR_16 PF13432.6 CBZ26766.1 - 0.056 14.1 4.5 3.1 8.5 1.4 3.9 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.6 CBZ26766.1 - 0.55 10.6 19.8 0.19 12.0 4.9 4.2 4 2 1 5 5 5 0 Tetratricopeptide repeat TPR_1 PF00515.28 CBZ26766.1 - 1 9.3 5.2 13 5.8 0.1 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat LRR_1 PF00560.33 CBZ26766.1 - 1.3 9.9 2.6 52 5.0 1.2 3.2 2 1 0 2 2 2 0 Leucine Rich Repeat MVP_shoulder PF11978.8 CBZ26768.1 - 1.2e-41 141.4 0.0 1.9e-41 140.8 0.0 1.3 1 0 0 1 1 1 1 Shoulder domain Vault_3 PF17795.1 CBZ26768.1 - 4e-33 113.2 0.2 2.7e-29 101.0 0.1 3.6 3 0 0 3 3 3 2 Major Vault Protein Repeat domain Vault PF01505.18 CBZ26768.1 - 1.7e-29 101.7 0.2 6.1e-13 48.7 0.0 4.4 4 0 0 4 4 4 3 Major Vault Protein repeat domain Vault_4 PF17796.1 CBZ26768.1 - 1e-16 60.8 0.0 7.9e-15 54.7 0.0 3.3 4 0 0 4 4 4 1 Major Vault Protein repeat domain Vault_2 PF17794.1 CBZ26768.1 - 1e-08 35.4 5.0 6.6e-05 23.2 0.0 4.2 3 1 0 3 3 3 2 Major Vault Protein repeat domain DUF3601 PF12208.8 CBZ26768.1 - 0.2 11.8 0.0 0.56 10.3 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3601) EF-hand_7 PF13499.6 CBZ26770.1 - 2.7e-10 40.5 0.1 7.6e-06 26.3 0.2 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 CBZ26770.1 - 9e-10 37.7 2.5 0.00092 19.0 0.0 3.3 3 1 0 3 3 3 2 EF-hand domain EF-hand_8 PF13833.6 CBZ26770.1 - 1.1e-09 37.9 0.0 3.1e-05 23.7 0.1 3.2 1 1 2 3 3 3 3 EF-hand domain pair EF-hand_1 PF00036.32 CBZ26770.1 - 4.4e-09 35.2 0.1 0.014 14.9 0.0 3.5 4 0 0 4 4 4 2 EF hand EF-hand_9 PF14658.6 CBZ26770.1 - 4.1e-05 23.8 0.3 0.0026 18.1 0.0 2.8 2 1 1 3 3 3 1 EF-hand domain EF-hand_5 PF13202.6 CBZ26770.1 - 0.0058 16.1 1.0 0.64 9.6 0.0 2.8 2 1 0 2 2 2 1 EF hand Dehydratase_SU PF02287.15 CBZ26770.1 - 0.043 13.9 0.0 0.067 13.3 0.0 1.3 1 0 0 1 1 1 0 Dehydratase small subunit SPARC_Ca_bdg PF10591.9 CBZ26770.1 - 0.046 14.1 0.0 1.2 9.5 0.0 2.1 1 1 1 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region Actin PF00022.19 CBZ26771.1 - 1.1e-33 116.4 0.0 2.5e-33 115.3 0.0 1.5 1 1 0 1 1 1 1 Actin FtsA PF14450.6 CBZ26771.1 - 0.12 12.8 0.0 0.26 11.7 0.0 1.6 1 1 0 1 1 1 0 Cell division protein FtsA MAGI_u5 PF16666.5 CBZ26771.1 - 0.54 10.4 6.5 5.2 7.2 1.4 2.3 2 0 0 2 2 2 0 Unstructured region on MAGI Hexokinase_1 PF00349.21 CBZ26772.1 - 2.1e-61 207.3 0.0 2.8e-61 206.9 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Hexokinase_2 PF03727.16 CBZ26772.1 - 2.2e-59 200.8 0.0 3.1e-59 200.3 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.21 CBZ26773.1 - 1.4e-61 207.9 0.0 1.9e-61 207.4 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Hexokinase_2 PF03727.16 CBZ26773.1 - 5.9e-60 202.7 0.0 8.3e-60 202.2 0.0 1.2 1 0 0 1 1 1 1 Hexokinase PPR_2 PF13041.6 CBZ26774.1 - 1.5e-14 53.9 3.1 3.4e-07 30.3 0.0 4.5 5 0 0 5 5 5 2 PPR repeat family PPR_3 PF13812.6 CBZ26774.1 - 4.6e-11 42.6 0.2 9e-07 28.9 0.0 4.6 5 0 0 5 5 5 1 Pentatricopeptide repeat domain PPR_long PF17177.4 CBZ26774.1 - 7.1e-07 28.8 0.6 0.00082 18.8 0.0 3.7 3 1 0 3 3 3 1 Pentacotripeptide-repeat region of PRORP PPR PF01535.20 CBZ26774.1 - 2.1e-06 27.6 5.3 5.3 7.5 0.1 6.3 7 0 0 7 7 7 2 PPR repeat PPR_1 PF12854.7 CBZ26774.1 - 0.0014 18.2 1.0 0.34 10.6 0.0 3.9 4 0 0 4 4 4 1 PPR repeat GMP_synt_C PF00958.22 CBZ26774.1 - 0.081 13.0 0.1 1.9 8.6 0.0 2.5 2 0 0 2 2 2 0 GMP synthase C terminal domain Pkinase PF00069.25 CBZ26775.1 - 2e-47 161.8 0.0 6.1e-46 156.9 0.0 2.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ26775.1 - 5.7e-30 104.4 0.0 6e-23 81.4 0.0 2.4 2 0 0 2 2 2 2 Protein tyrosine kinase RIO1 PF01163.22 CBZ26775.1 - 3.6e-05 23.4 0.1 7.7e-05 22.4 0.1 1.5 1 0 0 1 1 1 1 RIO1 family APH PF01636.23 CBZ26775.1 - 0.033 14.1 10.6 0.72 9.7 0.1 3.8 3 2 1 4 4 4 0 Phosphotransferase enzyme family Kinase-like PF14531.6 CBZ26775.1 - 0.071 12.4 0.0 7.7 5.7 0.0 2.3 2 0 0 2 2 2 0 Kinase-like LRR_4 PF12799.7 CBZ26777.1 - 0.03 14.7 0.2 5 7.7 0.0 2.5 2 0 0 2 2 2 0 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 CBZ26777.1 - 0.13 11.8 0.1 0.27 10.7 0.1 1.5 1 0 0 1 1 1 0 Leucine-rich repeat DUF702 PF05142.12 CBZ26779.1 - 0.02 15.3 0.5 0.038 14.5 0.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF702) zf-U1 PF06220.12 CBZ26780.1 - 7.7e-05 22.4 5.2 0.00018 21.2 5.2 1.6 1 0 0 1 1 1 1 U1 zinc finger AKAP95 PF04988.12 CBZ26780.1 - 0.0015 18.8 0.4 0.0022 18.2 0.4 1.2 1 0 0 1 1 1 1 A-kinase anchoring protein 95 (AKAP95) zf-C2H2_jaz PF12171.8 CBZ26780.1 - 0.011 16.0 0.7 0.03 14.6 0.7 1.8 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding Vps51 PF08700.11 CBZ26781.1 - 4.7e-23 81.1 1.2 4.7e-23 81.1 1.2 2.2 2 0 0 2 2 2 1 Vps51/Vps67 Sec5 PF15469.6 CBZ26781.1 - 1.7e-07 31.2 0.7 3.3e-07 30.3 0.3 1.6 2 0 0 2 2 2 1 Exocyst complex component Sec5 Dor1 PF04124.12 CBZ26781.1 - 9.1e-07 27.9 2.3 1.8e-06 26.9 2.3 1.4 1 0 0 1 1 1 1 Dor1-like family Vps53_N PF04100.12 CBZ26781.1 - 8.3e-06 25.0 2.6 1.5e-05 24.2 2.6 1.3 1 0 0 1 1 1 1 Vps53-like, N-terminal COG2 PF06148.11 CBZ26781.1 - 0.0001 22.4 1.6 0.00047 20.2 1.6 2.1 1 0 0 1 1 1 1 COG (conserved oligomeric Golgi) complex component, COG2 Vps54_N PF10475.9 CBZ26781.1 - 0.0027 17.1 3.6 0.0049 16.2 3.6 1.3 1 0 0 1 1 1 1 Vacuolar-sorting protein 54, of GARP complex CENP-F_leu_zip PF10473.9 CBZ26781.1 - 0.0042 17.1 2.0 0.014 15.4 2.0 1.9 1 0 0 1 1 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 COG5 PF10392.9 CBZ26781.1 - 0.0054 16.9 2.5 0.0054 16.9 2.5 2.4 3 0 0 3 3 2 1 Golgi transport complex subunit 5 SEO_N PF14576.6 CBZ26781.1 - 0.024 13.8 1.7 0.11 11.6 0.7 2.1 2 0 0 2 2 2 0 Sieve element occlusion N-terminus Occludin_ELL PF07303.13 CBZ26781.1 - 0.064 14.0 0.7 0.2 12.4 0.1 2.2 2 0 0 2 2 1 0 Occludin homology domain BLOC1_2 PF10046.9 CBZ26781.1 - 0.13 12.5 2.3 0.2 12.0 0.5 2.3 3 0 0 3 3 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 NPV_P10 PF05531.12 CBZ26781.1 - 0.42 11.1 3.4 1.7 9.2 0.6 3.2 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein Peptidase_M16 PF00675.20 CBZ26782.1 - 3.6e-09 36.8 0.0 8e-09 35.6 0.0 1.6 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 CBZ26782.1 - 0.0015 18.5 0.1 0.044 13.8 0.0 3.0 3 1 0 3 3 3 1 Peptidase M16 inactive domain MCU PF04678.13 CBZ26783.1 - 2e-18 67.1 4.6 2.3e-18 66.9 4.6 1.0 1 0 0 1 1 1 1 Mitochondrial calcium uniporter CCDC92 PF14916.6 CBZ26784.1 - 0.046 13.5 0.1 0.096 12.5 0.1 1.5 1 0 0 1 1 1 0 Coiled-coil domain of unknown function KinB_sensor PF16767.5 CBZ26784.1 - 3.5 8.1 7.7 2.2 8.8 1.6 2.4 1 1 1 2 2 2 0 Sensor domain of alginate biosynthesis sensor protein KinB NYD-SP28 PF14772.6 CBZ26784.1 - 3.9 7.6 7.7 0.19 11.8 2.1 1.7 2 0 0 2 2 2 0 Sperm tail RPAP2_Rtr1 PF04181.13 CBZ26785.1 - 2e-06 28.0 0.3 0.00024 21.3 0.0 2.5 2 1 0 2 2 2 2 Rtr1/RPAP2 family DUF667 PF05018.13 CBZ26786.1 - 7.5e-92 306.1 0.6 8.5e-92 306.0 0.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF667) UCH PF00443.29 CBZ26788.1 - 3.9e-46 157.6 0.4 5e-46 157.3 0.4 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 CBZ26788.1 - 2.4e-19 70.1 2.5 5.8e-19 68.8 2.5 1.6 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Alpha-2-MRAP_N PF06400.11 CBZ26788.1 - 0.011 15.7 3.4 0.021 14.8 3.4 1.4 1 0 0 1 1 1 0 Alpha-2-macroglobulin RAP, N-terminal domain Piwi PF02171.17 CBZ26789.1 - 2.6e-07 30.2 0.0 3.8e-07 29.6 0.0 1.2 1 0 0 1 1 1 1 Piwi domain Pyr_redox_2 PF07992.14 CBZ26790.1 - 5.3e-10 39.0 0.3 0.00013 21.3 0.0 3.3 2 1 1 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 CBZ26790.1 - 2.5e-05 24.4 0.0 0.00018 21.6 0.0 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 CBZ26790.1 - 0.00061 19.8 0.0 0.0014 18.6 0.0 1.7 1 0 0 1 1 1 1 FAD-NAD(P)-binding Pyr_redox PF00070.27 CBZ26790.1 - 0.0016 19.0 0.0 0.49 11.0 0.0 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.20 CBZ26790.1 - 0.007 16.4 0.6 19 5.3 0.0 3.4 3 0 0 3 3 3 2 Shikimate / quinate 5-dehydrogenase Lycopene_cycl PF05834.12 CBZ26790.1 - 0.036 13.1 0.3 0.076 12.0 0.0 1.7 2 0 0 2 2 2 0 Lycopene cyclase protein K_oxygenase PF13434.6 CBZ26790.1 - 0.041 13.0 0.0 1.1 8.4 0.0 2.2 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) TFIIA PF03153.13 CBZ26791.1 - 0.46 10.4 8.3 0.6 10.0 8.3 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit TMEM189_B_dmain PF10520.9 CBZ26792.1 - 1.2e-66 224.1 2.7 1.7e-66 223.6 2.7 1.1 1 0 0 1 1 1 1 B domain of TMEM189, localisation domain IBV_3A PF03617.13 CBZ26792.1 - 0.089 12.8 0.6 0.18 11.8 0.6 1.5 1 0 0 1 1 1 0 IBV 3A protein Vps35 PF03635.17 CBZ26795.1 - 3.9e-210 700.1 0.0 4.5e-210 699.9 0.0 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 35 Sigma70_ner PF04546.13 CBZ26795.1 - 0.56 10.0 4.2 0.26 11.1 0.6 2.1 2 0 0 2 2 2 0 Sigma-70, non-essential region GPS2_interact PF15784.5 CBZ26796.1 - 0.021 15.2 1.3 0.05 14.0 1.3 1.7 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DUF4795 PF16043.5 CBZ26796.1 - 0.078 12.6 8.3 0.3 10.6 0.0 3.3 2 1 1 3 3 3 0 Domain of unknown function (DUF4795) BRE1 PF08647.11 CBZ26796.1 - 0.23 11.5 8.2 0.33 11.1 0.0 3.1 3 0 0 3 3 3 0 BRE1 E3 ubiquitin ligase YabA PF06156.13 CBZ26796.1 - 0.5 11.0 7.9 1.6 9.4 0.4 4.0 5 0 0 5 5 5 0 Initiation control protein YabA Csm1_N PF18504.1 CBZ26796.1 - 1.1 9.6 15.4 12 6.3 0.1 5.5 4 1 2 6 6 6 0 Csm1 N-terminal domain Occludin_ELL PF07303.13 CBZ26796.1 - 1.8 9.4 8.0 15 6.4 0.3 3.6 2 1 1 3 3 3 0 Occludin homology domain DUF812 PF05667.11 CBZ26796.1 - 2.5 6.9 15.8 5.3 5.8 15.8 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF812) Tropomyosin PF00261.20 CBZ26796.1 - 4.6 6.5 23.8 0.45 9.9 0.1 3.9 2 1 1 3 3 3 0 Tropomyosin DnaJ_C PF01556.18 CBZ26797.1 - 1.3e-31 109.7 0.0 1.9e-31 109.2 0.0 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 CBZ26797.1 - 5.7e-27 93.6 1.5 1e-26 92.8 1.5 1.4 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 CBZ26797.1 - 3.3e-14 53.0 13.4 6.5e-14 52.0 13.4 1.5 1 0 0 1 1 1 1 DnaJ central domain DZR PF12773.7 CBZ26797.1 - 0.0099 15.9 5.9 0.25 11.4 0.4 2.3 2 0 0 2 2 2 2 Double zinc ribbon Anti-TRAP PF15777.5 CBZ26797.1 - 0.028 14.4 13.2 0.61 10.1 0.7 2.7 1 1 1 2 2 2 0 Tryptophan RNA-binding attenuator protein inhibitory protein HypA PF01155.19 CBZ26797.1 - 7.9 6.5 7.4 3.8 7.6 1.1 2.4 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA UPF0253 PF06786.12 CBZ26799.1 - 8.2 6.8 6.6 7 7.0 3.1 2.5 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0253) PQQ_3 PF13570.6 CBZ26800.1 - 0.034 14.7 1.8 0.24 11.9 0.1 3.3 3 0 0 3 3 3 0 PQQ-like domain TPR_14 PF13428.6 CBZ26801.1 - 9.9e-15 54.0 20.6 0.018 15.8 0.1 8.7 6 2 2 8 8 8 5 Tetratricopeptide repeat TPR_19 PF14559.6 CBZ26801.1 - 1.6e-14 54.2 13.0 9.6e-05 22.8 0.0 6.4 5 1 1 6 6 6 4 Tetratricopeptide repeat TPR_2 PF07719.17 CBZ26801.1 - 1.7e-10 40.1 15.2 0.012 15.6 0.5 7.5 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_1 PF00515.28 CBZ26801.1 - 5.1e-10 38.8 5.0 0.013 15.3 0.5 6.0 6 0 0 6 6 6 3 Tetratricopeptide repeat ANAPC3 PF12895.7 CBZ26801.1 - 3.9e-07 30.2 13.3 0.046 13.9 0.0 5.5 4 2 2 6 6 6 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.6 CBZ26801.1 - 5.8e-06 26.5 18.9 0.43 10.9 0.2 6.2 5 1 1 6 6 6 3 Tetratricopeptide repeat TPR_8 PF13181.6 CBZ26801.1 - 5e-05 23.2 2.3 1.1 9.6 0.1 4.8 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.6 CBZ26801.1 - 9.9e-05 22.1 4.7 17 5.7 0.1 5.5 5 0 0 5 5 5 0 Tetratricopeptide repeat HrpB1_HrpK PF09613.10 CBZ26801.1 - 0.00073 19.2 0.8 0.24 11.0 0.0 4.0 4 1 1 5 5 5 1 Bacterial type III secretion protein (HrpB1_HrpK) TPR_16 PF13432.6 CBZ26801.1 - 0.0056 17.3 0.4 0.0056 17.3 0.4 7.5 7 1 1 8 8 7 1 Tetratricopeptide repeat TPR_9 PF13371.6 CBZ26801.1 - 0.0084 16.2 11.8 0.018 15.1 0.3 4.7 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_11 PF13414.6 CBZ26801.1 - 0.024 14.3 6.7 9 6.1 0.0 4.7 5 0 0 5 5 5 0 TPR repeat Paf67 PF10255.9 CBZ26801.1 - 0.046 12.7 0.0 20 4.1 0.0 2.9 3 0 0 3 3 3 0 RNA polymerase I-associated factor PAF67 TPR_10 PF13374.6 CBZ26801.1 - 0.069 13.0 9.9 1.2 9.2 0.2 4.6 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_6 PF13174.6 CBZ26801.1 - 0.86 10.4 12.0 24 5.8 0.1 5.4 6 0 0 6 6 6 0 Tetratricopeptide repeat La PF05383.17 CBZ26802.1 - 1.2e-21 76.6 0.0 2.3e-21 75.6 0.0 1.5 1 0 0 1 1 1 1 La domain RRM_1 PF00076.22 CBZ26802.1 - 8.3e-05 22.3 0.2 0.0087 15.9 0.1 3.2 2 1 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 CBZ26802.1 - 0.0015 18.6 1.0 0.0095 16.0 0.3 2.5 3 0 0 3 3 3 1 RNA binding motif RRM_7 PF16367.5 CBZ26802.1 - 0.0032 17.6 0.1 0.052 13.7 0.1 2.2 2 0 0 2 2 2 1 RNA recognition motif PTS_2-RNA PF01885.16 CBZ26802.1 - 0.13 12.4 0.0 0.25 11.4 0.0 1.4 1 0 0 1 1 1 0 RNA 2'-phosphotransferase, Tpt1 / KptA family Pallilysin PF18663.1 CBZ26802.1 - 0.19 11.7 0.0 0.4 10.7 0.0 1.5 1 0 0 1 1 1 0 Pallilysin beta barrel domain API5 PF05918.11 CBZ26802.1 - 2.4 6.9 5.0 0.54 9.0 1.8 1.5 2 0 0 2 2 2 0 Apoptosis inhibitory protein 5 (API5) Biotin_lipoyl PF00364.22 CBZ26803.1 - 2.6e-26 91.2 1.3 6.7e-12 45.1 0.1 2.4 2 0 0 2 2 2 2 Biotin-requiring enzyme HlyD_3 PF13437.6 CBZ26803.1 - 0.00078 20.1 0.3 3 8.6 0.0 2.9 2 1 0 2 2 2 2 HlyD family secretion protein PYNP_C PF07831.13 CBZ26803.1 - 0.0042 16.7 0.3 4.9 6.9 0.0 2.8 3 0 0 3 3 3 2 Pyrimidine nucleoside phosphorylase C-terminal domain E3_binding PF02817.17 CBZ26803.1 - 0.0083 16.4 0.2 0.029 14.7 0.2 2.0 1 1 0 1 1 1 1 e3 binding domain DUF2118 PF09891.9 CBZ26803.1 - 0.014 15.4 0.2 7.1 6.6 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2118) DUF2779 PF11074.8 CBZ26803.1 - 0.025 15.1 0.0 3.9 8.0 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function(DUF2779) QRPTase_N PF02749.16 CBZ26803.1 - 0.038 14.1 0.1 12 6.0 0.0 2.7 2 0 0 2 2 2 0 Quinolinate phosphoribosyl transferase, N-terminal domain Membrane_bind PF14564.6 CBZ26803.1 - 0.17 12.3 0.1 31 5.0 0.0 2.3 2 0 0 2 2 2 0 Membrane binding E2_bind PF08825.10 CBZ26803.1 - 0.23 11.6 0.0 39 4.5 0.0 2.5 2 0 0 2 2 2 0 E2 binding domain DUF2969 PF11184.8 CBZ26803.1 - 0.3 11.5 1.3 31 5.1 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2969) TALPID3 PF15324.6 CBZ26803.1 - 1.5 6.4 9.9 0.66 7.6 1.1 2.1 2 0 0 2 2 2 0 Hedgehog signalling target CadC_C1 PF18500.1 CBZ26804.1 - 0.022 14.9 0.1 0.029 14.5 0.1 1.2 1 0 0 1 1 1 0 CadC C-terminal domain 1 SNARE PF05739.19 CBZ26804.1 - 0.044 13.8 1.4 0.11 12.5 0.7 1.9 2 0 0 2 2 2 0 SNARE domain TPR_MLP1_2 PF07926.12 CBZ26805.1 - 0.35 10.9 2.1 0.62 10.1 2.1 1.3 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein CTD_bind PF04818.13 CBZ26806.1 - 0.092 13.6 0.0 0.38 11.6 0.0 2.1 2 0 0 2 2 2 0 RNA polymerase II-binding domain. PilZ_2 PF16823.5 CBZ26807.1 - 0.13 12.4 0.4 13 6.0 0.0 2.3 1 1 1 2 2 2 0 Atypical PilZ domain, cyclic di-GMP receptor Ciart PF15673.5 CBZ26807.1 - 0.16 11.3 1.4 0.37 10.1 1.4 1.5 1 0 0 1 1 1 0 Circadian-associated transcriptional repressor DUF4916 PF16262.5 CBZ26808.1 - 0.027 14.0 0.7 0.065 12.7 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4916) DEAD PF00270.29 CBZ26809.1 - 6.3e-15 55.4 0.0 2.1e-11 43.9 0.0 2.7 2 0 0 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.31 CBZ26809.1 - 1.2e-14 54.6 0.1 5.6e-14 52.4 0.0 2.2 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 CBZ26809.1 - 0.0014 18.7 0.0 0.0035 17.4 0.0 1.6 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit Adeno_E3_15_3 PF03307.14 CBZ26809.1 - 0.14 12.1 0.0 0.31 11.0 0.0 1.5 1 0 0 1 1 1 0 Adenovirus 15.3kD protein in E3 region IMS PF00817.20 CBZ26810.1 - 7.6e-47 159.1 0.2 1.2e-46 158.5 0.2 1.3 1 0 0 1 1 1 1 impB/mucB/samB family IMS_HHH PF11798.8 CBZ26810.1 - 0.01 16.1 0.0 0.023 15.0 0.0 1.6 1 0 0 1 1 1 0 IMS family HHH motif PGM_PMM_I PF02878.16 CBZ26811.1 - 1.5e-30 105.7 0.1 2.5e-30 105.0 0.1 1.4 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_III PF02880.16 CBZ26811.1 - 2.6e-25 88.8 0.0 5.6e-25 87.8 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.16 CBZ26811.1 - 1.1e-09 38.8 0.2 9.3e-09 35.8 0.2 2.5 1 1 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.20 CBZ26811.1 - 2.8e-09 37.0 0.0 7.5e-09 35.7 0.0 1.7 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain ParA PF10609.9 CBZ26813.1 - 2e-88 296.0 0.0 2.3e-88 295.8 0.0 1.1 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 CBZ26813.1 - 9e-12 45.2 0.0 9e-11 41.9 0.0 2.4 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.6 CBZ26813.1 - 2.5e-07 30.8 0.5 4e-06 26.9 0.5 2.1 1 1 0 1 1 1 1 AAA domain MipZ PF09140.11 CBZ26813.1 - 8.6e-07 28.5 0.0 1.4e-06 27.8 0.0 1.3 1 1 0 1 1 1 1 ATPase MipZ ArsA_ATPase PF02374.15 CBZ26813.1 - 0.00023 20.5 0.5 0.00045 19.5 0.1 1.7 2 0 0 2 2 2 1 Anion-transporting ATPase MeaB PF03308.16 CBZ26813.1 - 0.0042 16.1 0.4 0.0068 15.4 0.4 1.2 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB RsgA_GTPase PF03193.16 CBZ26813.1 - 0.01 15.8 0.1 0.026 14.4 0.1 1.6 1 0 0 1 1 1 0 RsgA GTPase NB-ARC PF00931.22 CBZ26813.1 - 0.035 13.3 0.2 0.058 12.6 0.2 1.3 1 0 0 1 1 1 0 NB-ARC domain AAA_18 PF13238.6 CBZ26813.1 - 0.039 14.5 0.0 0.062 13.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_26 PF13500.6 CBZ26813.1 - 0.04 13.7 0.5 0.26 11.1 0.5 2.2 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.6 CBZ26813.1 - 0.04 13.5 0.0 0.064 12.8 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 CBZ26813.1 - 0.041 14.3 0.2 0.074 13.4 0.2 1.4 1 0 0 1 1 1 0 AAA ATPase domain Fer4_NifH PF00142.18 CBZ26813.1 - 0.047 13.1 0.2 0.099 12.1 0.2 1.5 1 0 0 1 1 1 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family AAA_30 PF13604.6 CBZ26813.1 - 0.047 13.4 0.9 0.11 12.2 0.2 1.9 2 0 0 2 2 2 0 AAA domain Rad17 PF03215.15 CBZ26813.1 - 0.086 12.7 0.1 0.26 11.2 0.1 1.7 2 0 0 2 2 2 0 Rad17 P-loop domain NACHT PF05729.12 CBZ26813.1 - 0.18 11.7 0.6 0.31 10.9 0.6 1.4 1 0 0 1 1 1 0 NACHT domain SRP54 PF00448.22 CBZ26813.1 - 0.19 11.3 0.6 0.6 9.7 0.3 1.8 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain RNA_helicase PF00910.22 CBZ26813.1 - 0.19 12.1 0.2 0.36 11.3 0.2 1.4 1 0 0 1 1 1 0 RNA helicase CBP_BcsQ PF06564.12 CBZ26813.1 - 0.21 11.0 0.1 0.66 9.4 0.1 1.7 2 0 0 2 2 2 0 Cellulose biosynthesis protein BcsQ MSC PF09402.10 CBZ26813.1 - 1.9 7.9 5.5 2.7 7.4 5.5 1.2 1 0 0 1 1 1 0 Man1-Src1p-C-terminal domain Lactamase_B PF00753.27 CBZ26814.1 - 4e-20 72.7 0.2 8.6e-20 71.6 0.2 1.6 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily BLACT_WH PF17778.1 CBZ26814.1 - 1e-08 35.0 0.1 2.6e-08 33.7 0.1 1.7 1 0 0 1 1 1 1 Beta-lactamase associated winged helix domain Lactamase_B_2 PF12706.7 CBZ26814.1 - 1.9e-05 24.3 0.3 5.6e-05 22.7 0.1 1.9 2 1 0 2 2 2 1 Beta-lactamase superfamily domain STAR_dimer PF16544.5 CBZ26814.1 - 0.0049 16.4 0.0 0.012 15.2 0.0 1.6 1 0 0 1 1 1 1 Homodimerisation region of STAR domain protein Lactamase_B_3 PF13483.6 CBZ26814.1 - 0.011 15.6 0.0 0.022 14.7 0.0 1.5 1 0 0 1 1 1 0 Beta-lactamase superfamily domain Hist_deacetyl PF00850.19 CBZ26815.1 - 2.9e-67 227.3 0.1 3.9e-67 226.9 0.1 1.1 1 0 0 1 1 1 1 Histone deacetylase domain DSPc PF00782.20 CBZ26817.1 - 1.3e-18 67.1 0.0 1.8e-18 66.6 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain ABC_tran PF00005.27 CBZ26818.1 - 1.1e-36 126.3 0.0 9.1e-18 65.1 0.0 2.4 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 CBZ26818.1 - 7.2e-11 42.4 2.3 0.0059 16.5 0.0 4.2 3 1 1 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 CBZ26818.1 - 1.6e-10 40.8 2.9 0.00099 18.6 0.2 3.9 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain RLI PF04068.15 CBZ26818.1 - 1.1e-09 37.9 6.1 3.2e-09 36.5 6.1 1.8 1 0 0 1 1 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI Fer4 PF00037.27 CBZ26818.1 - 1.1e-07 31.3 4.4 1.1e-07 31.3 2.2 2.3 2 0 0 2 2 2 1 4Fe-4S binding domain AAA_16 PF13191.6 CBZ26818.1 - 1.6e-06 28.6 0.0 0.0062 16.9 0.0 2.5 2 1 0 2 2 2 2 AAA ATPase domain AAA_15 PF13175.6 CBZ26818.1 - 3.1e-06 27.2 0.0 0.026 14.3 0.0 3.2 3 0 0 3 3 3 2 AAA ATPase domain AAA_23 PF13476.6 CBZ26818.1 - 1.1e-05 26.0 0.5 0.0097 16.4 0.2 2.4 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 CBZ26818.1 - 4.8e-05 23.0 0.4 0.16 11.7 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain Fer4_6 PF12837.7 CBZ26818.1 - 0.00011 22.1 2.3 0.00011 22.1 2.3 2.6 2 0 0 2 2 2 1 4Fe-4S binding domain Fer4_21 PF14697.6 CBZ26818.1 - 0.00014 21.9 14.9 0.00031 20.8 14.9 1.6 1 0 0 1 1 1 1 4Fe-4S dicluster domain AAA_22 PF13401.6 CBZ26818.1 - 0.00025 21.3 0.2 0.037 14.3 0.0 2.6 2 0 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 CBZ26818.1 - 0.00034 20.5 0.1 0.16 11.9 0.0 2.5 2 0 0 2 2 2 1 RsgA GTPase AAA_28 PF13521.6 CBZ26818.1 - 0.00052 20.3 0.0 1.1 9.5 0.0 2.9 3 0 0 3 3 3 1 AAA domain AAA PF00004.29 CBZ26818.1 - 0.00052 20.4 0.2 0.034 14.6 0.0 2.6 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) NACHT PF05729.12 CBZ26818.1 - 0.00083 19.3 0.3 0.022 14.7 0.0 2.4 2 0 0 2 2 2 1 NACHT domain Rad17 PF03215.15 CBZ26818.1 - 0.00099 19.1 0.0 0.87 9.5 0.0 2.5 2 0 0 2 2 2 1 Rad17 P-loop domain AAA_30 PF13604.6 CBZ26818.1 - 0.001 18.8 0.0 1.1 8.9 0.0 2.5 2 0 0 2 2 2 2 AAA domain Fer4_7 PF12838.7 CBZ26818.1 - 0.0013 19.3 0.2 0.0013 19.3 0.2 2.6 2 0 0 2 2 2 1 4Fe-4S dicluster domain RNA_helicase PF00910.22 CBZ26818.1 - 0.0015 18.9 0.0 0.52 10.7 0.0 3.0 3 0 0 3 3 2 1 RNA helicase AAA_5 PF07728.14 CBZ26818.1 - 0.0017 18.3 0.3 0.55 10.2 0.0 3.0 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) Fer4_10 PF13237.6 CBZ26818.1 - 0.0027 17.8 1.3 0.0027 17.8 1.3 2.4 1 1 1 2 2 2 2 4Fe-4S dicluster domain TsaE PF02367.17 CBZ26818.1 - 0.0042 17.1 0.0 0.019 15.0 0.0 1.9 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE SRP54 PF00448.22 CBZ26818.1 - 0.0044 16.7 0.3 0.66 9.6 0.0 2.3 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain AAA_33 PF13671.6 CBZ26818.1 - 0.0071 16.5 0.0 3.6 7.8 0.0 2.8 3 0 0 3 3 2 1 AAA domain AAA_7 PF12775.7 CBZ26818.1 - 0.0074 15.8 0.1 0.35 10.4 0.0 2.6 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_24 PF13479.6 CBZ26818.1 - 0.0098 15.6 0.1 0.97 9.1 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.6 CBZ26818.1 - 0.0099 15.5 0.1 3.3 7.3 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 CBZ26818.1 - 0.014 16.0 0.0 6.6 7.3 0.0 2.7 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 CBZ26818.1 - 0.016 15.2 0.0 4.4 7.4 0.0 2.7 2 0 0 2 2 2 0 50S ribosome-binding GTPase Fer4_3 PF12798.7 CBZ26818.1 - 0.031 15.2 4.0 0.031 15.2 4.0 2.7 2 0 0 2 2 1 0 4Fe-4S binding domain AAA_14 PF13173.6 CBZ26818.1 - 0.032 14.2 0.0 1.1 9.3 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.6 CBZ26818.1 - 0.039 14.3 0.2 1.6 9.1 0.0 2.6 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 CBZ26818.1 - 0.042 13.1 0.0 4.9 6.4 0.0 2.7 2 0 0 2 2 2 0 Zeta toxin AAA_27 PF13514.6 CBZ26818.1 - 0.051 13.2 0.0 0.77 9.3 0.0 2.2 2 0 0 2 2 2 0 AAA domain Fer4_9 PF13187.6 CBZ26818.1 - 0.12 12.6 14.5 0.38 10.9 14.7 1.9 1 1 0 1 1 1 0 4Fe-4S dicluster domain Thymidylate_kin PF02223.17 CBZ26818.1 - 0.13 11.9 0.2 15 5.2 0.0 3.2 3 0 0 3 3 3 0 Thymidylate kinase NB-ARC PF00931.22 CBZ26818.1 - 0.14 11.4 0.3 6.9 5.8 0.0 2.8 3 0 0 3 3 3 0 NB-ARC domain PduV-EutP PF10662.9 CBZ26818.1 - 0.44 10.3 1.5 1.2 8.9 0.0 2.5 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation MukB PF04310.12 CBZ26818.1 - 1.9 8.2 3.9 23 4.7 0.1 3.2 4 0 0 4 4 4 0 MukB N-terminal Stork_head PF10264.9 CBZ26819.1 - 0.056 13.6 0.1 0.16 12.2 0.1 1.7 1 0 0 1 1 1 0 Winged helix Storkhead-box1 domain Hpt PF01627.23 CBZ26819.1 - 0.064 13.5 0.1 0.064 13.5 0.1 2.3 3 0 0 3 3 3 0 Hpt domain Dabb PF07876.12 CBZ26819.1 - 0.088 13.4 0.1 2.8 8.6 0.0 2.4 2 0 0 2 2 2 0 Stress responsive A/B Barrel Domain Leu_Phe_trans PF03588.14 CBZ26820.1 - 0.007 15.9 0.0 0.085 12.4 0.0 2.4 3 0 0 3 3 3 1 Leucyl/phenylalanyl-tRNA protein transferase Ribosomal_L36e PF01158.18 CBZ26821.1 - 1.5e-28 98.9 1.8 1.7e-28 98.7 1.8 1.0 1 0 0 1 1 1 1 Ribosomal protein L36e DUF543 PF04418.12 CBZ26822.1 - 4.5e-14 52.2 0.5 5.4e-14 51.9 0.5 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF543) ParA PF10609.9 CBZ26822.1 - 0.015 14.8 0.0 0.024 14.1 0.0 1.3 1 1 0 1 1 1 0 NUBPL iron-transfer P-loop NTPase ATP-synt_C PF00137.21 CBZ26823.1 - 2e-07 31.3 13.4 2e-07 31.3 13.4 1.5 2 0 0 2 2 2 1 ATP synthase subunit C PCI PF01399.27 CBZ26825.1 - 7.3e-13 48.9 1.3 1.6e-12 47.9 0.2 2.2 2 0 0 2 2 2 1 PCI domain RPN5_C PF18098.1 CBZ26825.1 - 5.2e-05 23.3 0.7 0.0003 20.8 0.3 2.4 2 0 0 2 2 2 1 26S proteasome regulatory subunit RPN5 C-terminal domain Ras PF00071.22 CBZ26828.1 - 1.4e-45 154.8 0.0 1.7e-45 154.5 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CBZ26828.1 - 1e-33 116.1 0.0 1.5e-33 115.6 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CBZ26828.1 - 1.2e-10 41.1 0.0 2.5e-10 40.1 0.0 1.5 1 1 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 CBZ26828.1 - 6.7e-06 25.8 0.0 2e-05 24.2 0.0 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 CBZ26828.1 - 8.9e-05 22.4 0.0 0.025 14.5 0.0 2.1 2 0 0 2 2 2 2 RsgA GTPase Gtr1_RagA PF04670.12 CBZ26828.1 - 0.00082 18.8 0.0 0.0011 18.4 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 CBZ26828.1 - 0.0018 18.4 0.0 0.0028 17.7 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 CBZ26828.1 - 0.02 14.4 0.0 0.053 12.9 0.0 1.6 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit AAA_22 PF13401.6 CBZ26828.1 - 0.038 14.2 0.0 0.09 13.0 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.6 CBZ26828.1 - 0.1 13.0 0.1 0.16 12.3 0.1 1.5 1 1 0 1 1 1 0 AAA ATPase domain DUF2617 PF10936.8 CBZ26828.1 - 0.13 12.3 0.1 0.21 11.6 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function DUF2617 Not1 PF04054.15 CBZ26830.1 - 2e-93 313.3 8.5 2.2e-93 313.1 7.0 1.8 2 0 0 2 2 2 1 CCR4-Not complex component, Not1 CNOT1_CAF1_bind PF16415.5 CBZ26830.1 - 5.6e-75 251.6 0.1 1.1e-74 250.7 0.1 1.5 1 0 0 1 1 1 1 CCR4-NOT transcription complex subunit 1 CAF1-binding domain CNOT1_TTP_bind PF16417.5 CBZ26830.1 - 1.6e-46 157.8 0.0 6.6e-46 155.9 0.0 2.1 2 0 0 2 2 2 1 CCR4-NOT transcription complex subunit 1 TTP binding domain DUF3819 PF12842.7 CBZ26830.1 - 2.2e-24 86.0 0.3 9.6e-24 84.0 0.3 2.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3819) tRNA-synt_1g PF09334.11 CBZ26831.1 - 2e-97 326.4 1.2 6.6e-97 324.7 1.2 1.7 1 1 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.22 CBZ26831.1 - 1.4e-17 63.2 2.7 2e-07 29.7 2.3 3.1 2 1 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1e PF01406.19 CBZ26831.1 - 5e-08 32.7 0.1 0.0025 17.2 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain MKT1_C PF12246.8 CBZ26832.1 - 3.2e-13 49.5 0.0 5.5e-13 48.7 0.0 1.2 1 0 0 1 1 1 1 Temperature dependent protein affecting M2 dsRNA replication MKT1_N PF12247.8 CBZ26832.1 - 2.1e-11 44.0 0.0 4.1e-11 43.1 0.0 1.5 1 0 0 1 1 1 1 Temperature dependent protein affecting M2 dsRNA replication Pkinase PF00069.25 CBZ26833.1 - 1.9e-40 138.9 0.0 2.6e-36 125.3 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ26833.1 - 2.9e-24 85.8 0.0 2.5e-14 53.2 0.0 3.6 4 0 0 4 4 4 3 Protein tyrosine kinase APH PF01636.23 CBZ26833.1 - 0.013 15.5 0.0 0.045 13.7 0.0 1.9 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 CBZ26833.1 - 0.018 13.9 0.0 0.027 13.3 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Pox_A_type_inc PF04508.12 CBZ26834.1 - 0.00027 20.7 15.6 1.4 8.9 0.2 11.9 11 0 0 11 11 11 1 Viral A-type inclusion protein repeat CODH_A_N PF18537.1 CBZ26834.1 - 1 9.4 4.5 15 5.7 0.1 5.7 3 0 0 3 3 3 0 Carbon monoxide dehydrogenase subunit alpha N-terminal domain DUF4833 PF16117.5 CBZ26836.1 - 3.1e-18 66.1 0.2 1.5e-08 34.8 0.0 3.0 2 1 0 2 2 2 2 Domain of unknown function (DUF4833) DUF4833 PF16117.5 CBZ26837.1 - 2.6e-21 76.1 1.0 3.9e-10 39.9 0.1 3.1 2 1 0 2 2 2 2 Domain of unknown function (DUF4833) Peptidase_M24 PF00557.24 CBZ26838.1 - 2.2e-41 141.9 0.1 3.1e-41 141.4 0.1 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 BAF1_ABF1 PF04684.13 CBZ26838.1 - 0.16 11.0 2.4 0.28 10.2 2.4 1.3 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor IHABP4_N PF16174.5 CBZ26838.1 - 1.2 9.7 7.3 0.82 10.3 5.4 1.7 1 1 0 1 1 1 0 Intracellular hyaluronan-binding protein 4 N-terminal DUF2730 PF10805.8 CBZ26839.1 - 0.096 12.8 1.5 0.23 11.5 0.1 2.2 2 1 1 3 3 3 0 Protein of unknown function (DUF2730) RCR PF12273.8 CBZ26839.1 - 0.1 13.2 0.8 0.64 10.7 0.0 2.2 2 0 0 2 2 2 0 Chitin synthesis regulation, resistance to Congo red MWFE PF15879.5 CBZ26839.1 - 0.45 10.7 3.3 15 5.8 0.0 2.8 3 0 0 3 3 3 0 NADH-ubiquinone oxidoreductase MWFE subunit Pribosyltran PF00156.27 CBZ26840.1 - 5.9e-20 71.4 0.1 6.9e-20 71.2 0.1 1.1 1 0 0 1 1 1 1 Phosphoribosyl transferase domain Pribosyltran PF00156.27 CBZ26841.1 - 2.6e-18 66.0 0.0 3.7e-18 65.6 0.0 1.1 1 0 0 1 1 1 1 Phosphoribosyl transferase domain Pkinase PF00069.25 CBZ26842.1 - 9.4e-53 179.2 0.0 4.8e-37 127.8 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ26842.1 - 1e-26 93.8 0.0 1.9e-17 63.4 0.0 2.7 2 1 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 CBZ26842.1 - 8.6e-09 35.1 0.0 1.7e-08 34.1 0.0 1.4 1 0 0 1 1 1 1 Kinase-like BAG PF02179.16 CBZ26843.1 - 0.00034 21.0 0.1 0.00065 20.1 0.1 1.7 1 1 0 1 1 1 1 BAG domain HEAT PF02985.22 CBZ26847.1 - 0.038 14.3 1.4 1.6 9.2 0.0 4.0 5 0 0 5 5 5 0 HEAT repeat HEAT_2 PF13646.6 CBZ26847.1 - 0.09 13.2 1.5 0.32 11.4 1.0 2.3 3 0 0 3 3 3 0 HEAT repeats Pkinase PF00069.25 CBZ26847.1 - 0.13 11.6 0.0 0.27 10.5 0.0 1.5 1 1 0 1 1 1 0 Protein kinase domain HEAT_2 PF13646.6 CBZ26848.1 - 4.1e-10 39.9 1.2 0.00035 20.9 0.0 4.1 4 1 0 4 4 4 2 HEAT repeats DUF4042 PF13251.6 CBZ26848.1 - 9.4e-09 35.2 1.3 2.8e-05 23.9 0.3 4.6 4 1 0 4 4 4 1 Domain of unknown function (DUF4042) HEAT PF02985.22 CBZ26848.1 - 4.5e-05 23.3 4.6 1.1 9.8 0.0 6.4 5 0 0 5 5 5 1 HEAT repeat HEAT_EZ PF13513.6 CBZ26848.1 - 0.00026 21.4 16.7 0.069 13.7 0.2 6.8 5 2 1 6 6 6 2 HEAT-like repeat Cnd1 PF12717.7 CBZ26848.1 - 0.0035 17.4 0.0 0.008 16.2 0.0 1.6 1 0 0 1 1 1 1 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.20 CBZ26848.1 - 0.13 10.8 0.0 0.27 9.8 0.0 1.4 1 0 0 1 1 1 0 Adaptin N terminal region ABC2_membrane PF01061.24 CBZ26849.1 - 9.5e-07 28.4 17.2 1.5e-06 27.8 17.2 1.3 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.27 CBZ26849.1 - 3.2e-06 27.7 0.0 5.9e-06 26.8 0.0 1.4 1 0 0 1 1 1 1 ABC transporter PDR_CDR PF06422.12 CBZ26849.1 - 0.0063 16.4 0.0 0.024 14.5 0.0 2.0 1 0 0 1 1 1 1 CDR ABC transporter ATP1G1_PLM_MAT8 PF02038.16 CBZ26850.1 - 0.088 12.3 0.2 0.14 11.6 0.2 1.2 1 0 0 1 1 1 0 ATP1G1/PLM/MAT8 family DUF4499 PF14934.6 CBZ26851.1 - 1.1e-06 28.9 2.3 2e-06 28.0 2.3 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4499) MutS_V PF00488.21 CBZ26852.1 - 1.3e-31 110.1 0.0 4e-31 108.5 0.0 1.9 2 0 0 2 2 2 1 MutS domain V MutS_III PF05192.18 CBZ26852.1 - 3.9e-17 63.1 0.9 7.1e-16 59.0 0.9 2.4 1 1 0 1 1 1 1 MutS domain III AAA_21 PF13304.6 CBZ26852.1 - 0.0014 18.5 0.0 0.0029 17.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system MutS_II PF05188.17 CBZ26852.1 - 0.0017 18.6 0.1 0.0036 17.6 0.1 1.5 1 0 0 1 1 1 1 MutS domain II AAA_16 PF13191.6 CBZ26852.1 - 0.0056 17.1 0.0 0.0056 17.1 0.0 2.9 3 0 0 3 3 3 1 AAA ATPase domain ABC_tran PF00005.27 CBZ26852.1 - 0.013 16.1 0.0 0.028 14.9 0.0 1.5 1 0 0 1 1 1 0 ABC transporter AAA_14 PF13173.6 CBZ26852.1 - 0.027 14.5 0.0 0.05 13.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 CBZ26852.1 - 0.036 14.3 0.0 0.14 12.4 0.0 2.1 1 0 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 CBZ26852.1 - 0.15 12.0 0.0 0.26 11.2 0.0 1.2 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea MutS_IV PF05190.18 CBZ26852.1 - 0.17 12.2 0.0 0.75 10.2 0.0 2.1 3 0 0 3 3 2 0 MutS family domain IV AAA PF00004.29 CBZ26852.1 - 0.19 12.2 0.0 0.42 11.0 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_23 PF13476.6 CBZ26852.1 - 0.21 12.1 0.0 0.38 11.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain tRNA-synt_2 PF00152.20 CBZ26854.1 - 1.2e-63 215.1 0.0 4e-63 213.4 0.0 1.7 1 1 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 CBZ26854.1 - 1.1e-09 38.1 0.0 2e-09 37.3 0.0 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 CBZ26854.1 - 3.4e-06 26.7 0.2 0.01 15.3 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) tRNA_edit PF04073.15 CBZ26857.1 - 1.3e-07 31.7 0.0 2.6e-07 30.7 0.0 1.5 1 1 0 1 1 1 1 Aminoacyl-tRNA editing domain Sugarporin_N PF11471.8 CBZ26857.1 - 0.14 12.1 0.1 0.14 12.1 0.1 1.7 2 0 0 2 2 2 0 Maltoporin periplasmic N-terminal extension Histone PF00125.24 CBZ26859.1 - 3.3e-07 30.7 0.0 4.8e-07 30.2 0.0 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Histone_H2A_C PF16211.5 CBZ26859.1 - 1.2e-05 24.9 1.4 2.7e-05 23.8 1.4 1.6 1 0 0 1 1 1 1 C-terminus of histone H2A CBFD_NFYB_HMF PF00808.23 CBZ26859.1 - 0.016 15.4 0.0 0.036 14.4 0.0 1.5 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone DUF1583 PF07622.11 CBZ26859.1 - 0.14 10.8 0.0 0.16 10.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1583) PDCD2_C PF04194.13 CBZ26861.1 - 6.4e-27 94.7 0.1 6.4e-27 94.7 0.1 2.2 2 2 0 2 2 2 1 Programmed cell death protein 2, C-terminal putative domain Vps4_C PF09336.10 CBZ26861.1 - 0.21 11.6 0.9 0.4 10.7 0.3 1.7 2 0 0 2 2 2 0 Vps4 C terminal oligomerisation domain SET PF00856.28 CBZ26863.1 - 0.18 12.2 0.0 0.58 10.5 0.0 2.1 1 1 0 1 1 1 0 SET domain Clathrin PF00637.20 CBZ26864.1 - 1.6e-13 50.8 19.4 0.011 15.6 0.0 10.3 5 3 3 9 9 9 3 Region in Clathrin and VPS ANAPC4_WD40 PF12894.7 CBZ26864.1 - 1.1e-07 32.0 0.0 0.18 12.1 0.0 4.7 2 1 2 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain TPR_4 PF07721.14 CBZ26864.1 - 1.2e-06 28.5 5.2 1.1 10.0 0.0 8.2 7 1 1 8 8 8 1 Tetratricopeptide repeat WD40 PF00400.32 CBZ26864.1 - 1.6e-05 25.5 2.3 1.1 10.2 0.1 5.0 5 0 0 5 5 4 2 WD domain, G-beta repeat PPR PF01535.20 CBZ26864.1 - 4.7e-05 23.4 8.6 4.1 7.9 0.4 7.8 6 1 1 7 7 7 1 PPR repeat Coatomer_WDAD PF04053.14 CBZ26864.1 - 6.9e-05 22.1 11.0 0.0019 17.4 1.2 5.3 4 2 1 6 6 6 1 Coatomer WD associated region TPR_7 PF13176.6 CBZ26864.1 - 0.018 15.0 27.3 0.8 9.9 0.0 11.0 14 1 1 15 15 14 0 Tetratricopeptide repeat PTAC PF06130.12 CBZ26864.1 - 0.04 14.1 0.0 0.12 12.5 0.0 1.8 1 0 0 1 1 1 0 Phosphate propanoyltransferase TPR_2 PF07719.17 CBZ26864.1 - 0.044 13.9 0.1 0.044 13.9 0.1 11.3 13 0 0 13 13 10 0 Tetratricopeptide repeat PknG_rubred PF16919.5 CBZ26864.1 - 0.069 13.3 0.1 0.16 12.1 0.1 1.5 1 0 0 1 1 1 0 Protein kinase G rubredoxin domain DUF294_C PF10335.9 CBZ26864.1 - 0.079 12.8 0.3 0.2 11.4 0.3 1.7 1 0 0 1 1 1 0 Putative nucleotidyltransferase substrate binding domain PP_kinase_C_1 PF17941.1 CBZ26864.1 - 0.096 12.2 0.1 0.27 10.8 0.1 1.7 1 0 0 1 1 1 0 Polyphosphate kinase C-terminal domain 1 TPR_8 PF13181.6 CBZ26864.1 - 0.12 12.7 21.9 11 6.5 0.0 8.0 8 0 0 8 8 8 0 Tetratricopeptide repeat ANAPC3 PF12895.7 CBZ26864.1 - 0.18 12.1 0.0 0.18 12.1 0.0 6.7 7 3 2 9 9 9 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.6 CBZ26864.1 - 0.45 11.5 42.0 14 6.8 0.1 14.8 11 6 7 18 18 16 0 Tetratricopeptide repeat TPR_1 PF00515.28 CBZ26864.1 - 0.84 9.6 37.7 1.2 9.1 0.1 11.1 11 1 1 12 12 12 0 Tetratricopeptide repeat TPR_11 PF13414.6 CBZ26864.1 - 0.93 9.2 11.3 10 5.9 0.1 5.1 5 0 0 5 5 5 0 TPR repeat TPR_19 PF14559.6 CBZ26864.1 - 1.1 9.9 18.4 4.4 7.9 0.0 7.7 5 3 2 7 7 7 0 Tetratricopeptide repeat TPR_12 PF13424.6 CBZ26864.1 - 1.5 9.2 32.4 1.5 9.2 0.1 10.1 10 1 1 12 12 12 0 Tetratricopeptide repeat PPR_1 PF12854.7 CBZ26864.1 - 2.6 7.8 5.1 0.92 9.3 0.8 2.7 3 0 0 3 3 3 0 PPR repeat TPR_10 PF13374.6 CBZ26864.1 - 4.5 7.3 15.5 3.5 7.6 0.1 6.7 7 1 0 7 7 7 0 Tetratricopeptide repeat Tubulin PF00091.25 CBZ26867.1 - 4e-62 209.9 0.0 5.3e-62 209.5 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 CBZ26867.1 - 3.7e-23 82.1 0.0 5.8e-23 81.4 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_2 PF13809.6 CBZ26867.1 - 8.8e-05 21.8 0.0 0.00014 21.1 0.0 1.3 1 0 0 1 1 1 1 Tubulin like Bombesin PF02044.17 CBZ26867.1 - 0.16 12.1 1.2 0.36 11.0 1.2 1.6 1 0 0 1 1 1 0 Bombesin-like peptide Ax_dynein_light PF10211.9 CBZ26868.1 - 1.9e-48 164.9 1.6 2.9e-48 164.3 1.6 1.3 1 0 0 1 1 1 1 Axonemal dynein light chain Kinesin PF00225.23 CBZ26870.1 - 8.5e-85 284.6 0.4 1.5e-84 283.8 0.4 1.4 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 CBZ26870.1 - 1e-12 48.2 0.0 3e-12 46.7 0.0 1.8 1 0 0 1 1 1 1 Microtubule binding Exonuc_VII_L PF02601.15 CBZ26870.1 - 2.9 7.4 18.0 0.16 11.5 4.2 3.6 3 0 0 3 3 3 0 Exonuclease VII, large subunit Ribosomal_L6 PF00347.23 CBZ26871.1 - 7.5e-27 93.8 3.8 6.9e-15 55.5 0.7 2.1 2 0 0 2 2 2 2 Ribosomal protein L6 Ribosom_S12_S23 PF00164.25 CBZ26872.1 - 1.4e-48 163.3 0.5 1.4e-48 163.3 0.5 1.6 2 0 0 2 2 2 1 Ribosomal protein S12/S23 Ribosom_S12_S23 PF00164.25 CBZ26873.1 - 1.4e-48 163.3 0.5 1.4e-48 163.3 0.5 1.6 2 0 0 2 2 2 1 Ribosomal protein S12/S23 Pkinase PF00069.25 CBZ26874.1 - 7.6e-73 245.1 0.0 9e-73 244.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ26874.1 - 6.6e-34 117.4 0.0 8.3e-34 117.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 CBZ26874.1 - 0.00093 19.2 0.7 0.014 15.3 0.4 2.1 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kinase-like PF14531.6 CBZ26874.1 - 0.0019 17.6 0.0 0.038 13.3 0.0 2.1 1 1 1 2 2 2 1 Kinase-like Kdo PF06293.14 CBZ26874.1 - 0.0082 15.5 0.6 0.017 14.5 0.6 1.4 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 CBZ26874.1 - 0.086 11.8 0.0 10 4.9 0.0 2.1 2 0 0 2 2 2 0 Haspin like kinase domain Cpn60_TCP1 PF00118.24 CBZ26875.1 - 3.5e-143 477.8 8.8 4.3e-143 477.5 8.8 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Tau95 PF09734.9 CBZ26876.1 - 4.2e-20 73.0 0.0 7.1e-20 72.2 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase III transcription factor (TF)IIIC subunit HTH domain Tau95_N PF17682.1 CBZ26876.1 - 0.0016 18.7 0.0 0.034 14.3 0.0 2.6 2 0 0 2 2 2 1 Tau95 Triple barrel domain IQ PF00612.27 CBZ26877.1 - 3.6e-13 48.0 200.1 1.9e-05 24.0 0.1 25.1 25 1 2 27 27 27 14 IQ calmodulin-binding motif TPR_12 PF13424.6 CBZ26877.1 - 1.2e-05 25.5 18.9 0.00031 21.0 0.9 5.6 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_10 PF13374.6 CBZ26877.1 - 4e-05 23.3 11.7 0.047 13.6 0.2 5.6 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.28 CBZ26877.1 - 5.6e-05 22.8 0.0 0.98 9.3 0.0 4.1 3 0 0 3 3 3 2 Tetratricopeptide repeat WD40 PF00400.32 CBZ26878.1 - 7.9e-14 51.8 9.6 0.026 15.4 0.0 6.8 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBZ26878.1 - 5.6e-06 26.6 0.0 4.8 7.5 0.0 4.3 3 1 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Nbas_N PF15492.6 CBZ26878.1 - 0.0023 17.3 0.0 0.096 12.0 0.0 2.3 1 1 1 2 2 2 1 Neuroblastoma-amplified sequence, N terminal Nup160 PF11715.8 CBZ26878.1 - 0.014 14.1 0.0 0.033 12.8 0.0 1.6 1 0 0 1 1 1 0 Nucleoporin Nup120/160 Golgin_A5 PF09787.9 CBZ26879.1 - 0.00014 21.5 0.1 0.00014 21.5 0.1 4.1 3 1 1 4 4 4 2 Golgin subfamily A member 5 DUF2839 PF10999.8 CBZ26879.1 - 0.036 14.4 1.1 0.079 13.3 1.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2839) SHE3 PF17078.5 CBZ26879.1 - 2.7 7.7 13.2 8.7 6.0 6.5 2.6 2 1 0 2 2 2 0 SWI5-dependent HO expression protein 3 DUF948 PF06103.11 CBZ26879.1 - 3.4 8.0 6.0 7.8 6.8 0.1 3.5 4 0 0 4 4 4 0 Bacterial protein of unknown function (DUF948) DUF5021 PF16424.5 CBZ26881.1 - 0.11 12.3 1.6 9.1 6.1 0.6 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF5021) LRR_8 PF13855.6 CBZ26883.1 - 3e-24 84.5 25.8 6.1e-07 29.1 0.2 5.2 1 1 5 7 7 7 6 Leucine rich repeat LRR_4 PF12799.7 CBZ26883.1 - 3.9e-14 52.5 8.6 0.00062 20.1 0.2 5.5 3 2 5 8 8 8 6 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 CBZ26883.1 - 7.9e-06 25.7 4.3 12 6.9 0.0 7.7 9 1 0 9 9 9 1 Leucine Rich Repeat LRRNT_2 PF08263.12 CBZ26883.1 - 0.0028 17.9 0.2 0.011 16.1 0.2 2.0 1 0 0 1 1 1 1 Leucine rich repeat N-terminal domain Phage-tail_3 PF13550.6 CBZ26883.1 - 0.72 9.7 4.2 26 4.6 0.0 4.3 3 1 1 5 5 5 0 Putative phage tail protein Ribosomal_L1 PF00687.21 CBZ26884.1 - 4.7e-10 39.6 0.0 6e-05 22.9 0.0 2.0 2 0 0 2 2 2 2 Ribosomal protein L1p/L10e family PIF1 PF05970.14 CBZ26885.1 - 9.6e-34 117.1 0.0 3.8e-23 82.2 0.0 3.7 2 1 1 3 3 3 3 PIF1-like helicase AAA_30 PF13604.6 CBZ26885.1 - 4.9e-13 49.2 1.1 2.5e-09 37.1 0.7 2.4 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.6 CBZ26885.1 - 1.4e-10 41.7 0.1 7.8e-10 39.3 0.1 2.3 1 1 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 CBZ26885.1 - 4.9e-07 29.7 0.1 0.072 12.8 0.0 3.3 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase DEAD PF00270.29 CBZ26885.1 - 0.00012 21.9 0.1 0.0046 16.7 0.1 2.4 1 1 0 1 1 1 1 DEAD/DEAH box helicase Mg_chelatase PF01078.21 CBZ26885.1 - 0.00036 20.0 0.3 0.0007 19.0 0.3 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI UvrD_C_2 PF13538.6 CBZ26885.1 - 0.0015 18.3 0.1 0.0033 17.2 0.1 1.6 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_32 PF13654.6 CBZ26885.1 - 0.0051 15.7 0.0 0.0076 15.1 0.0 1.1 1 0 0 1 1 1 1 AAA domain UvrD-helicase PF00580.21 CBZ26885.1 - 0.0061 16.1 0.0 0.0098 15.4 0.0 1.3 1 0 0 1 1 1 1 UvrD/REP helicase N-terminal domain NTPase_1 PF03266.15 CBZ26885.1 - 0.0092 15.9 0.0 0.02 14.8 0.0 1.5 1 0 0 1 1 1 1 NTPase AAA_11 PF13086.6 CBZ26885.1 - 0.0093 15.8 0.3 0.14 11.9 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.14 CBZ26885.1 - 0.01 15.9 0.0 1.2 9.1 0.0 2.4 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 CBZ26885.1 - 0.011 16.1 0.3 0.039 14.3 0.3 2.0 1 1 0 1 1 1 0 AAA ATPase domain Herpes_Helicase PF02689.14 CBZ26885.1 - 0.014 13.3 0.1 0.061 11.2 0.0 1.9 3 0 0 3 3 3 0 Helicase AAA_7 PF12775.7 CBZ26885.1 - 0.014 14.9 0.0 0.85 9.1 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region DUF2075 PF09848.9 CBZ26885.1 - 0.023 13.9 0.0 0.085 12.1 0.0 1.8 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_24 PF13479.6 CBZ26885.1 - 0.049 13.4 0.0 0.14 11.8 0.0 1.8 1 1 0 1 1 1 0 AAA domain PhoH PF02562.16 CBZ26885.1 - 0.056 12.9 0.0 0.098 12.1 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein T2SSE PF00437.20 CBZ26885.1 - 0.11 11.5 0.0 0.2 10.7 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein ERM PF00769.19 CBZ26886.1 - 0.032 14.0 0.3 0.11 12.4 0.3 1.9 1 1 0 1 1 1 0 Ezrin/radixin/moesin family TK PF00265.18 CBZ26887.1 - 1.5e-61 207.4 0.7 1.9e-61 207.0 0.7 1.1 1 0 0 1 1 1 1 Thymidine kinase AAA_14 PF13173.6 CBZ26887.1 - 0.0016 18.5 0.0 0.0026 17.8 0.0 1.3 1 0 0 1 1 1 1 AAA domain PKcGMP_CC PF16808.5 CBZ26888.1 - 2.3e-05 24.1 15.0 0.02 14.7 0.3 6.0 4 1 1 5 5 5 3 Coiled-coil N-terminus of cGMP-dependent protein kinase Pox_A_type_inc PF04508.12 CBZ26888.1 - 0.0015 18.3 5.1 0.052 13.4 0.8 3.2 2 0 0 2 2 2 2 Viral A-type inclusion protein repeat BRE1 PF08647.11 CBZ26888.1 - 0.0041 17.1 3.7 0.0041 17.1 3.7 9.0 7 3 1 9 9 9 2 BRE1 E3 ubiquitin ligase ERM PF00769.19 CBZ26888.1 - 0.005 16.7 2.8 0.005 16.7 2.8 7.0 4 2 1 6 6 6 1 Ezrin/radixin/moesin family DUF5446 PF17522.2 CBZ26888.1 - 0.4 10.9 0.0 0.4 10.9 0.0 5.9 7 0 0 7 7 7 0 Family of unknown function (DUF5446) Spc42p PF11544.8 CBZ26888.1 - 5 7.2 7.0 1.6 8.7 0.1 3.8 3 0 0 3 3 3 0 Spindle pole body component Spc42p WD40 PF00400.32 CBZ26889.1 - 6.9e-12 45.7 9.2 4.2e-05 24.2 0.2 6.4 6 0 0 6 6 6 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBZ26889.1 - 0.0059 16.9 0.3 4.8 7.5 0.0 3.7 2 1 2 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain BBS2_Mid PF14783.6 CBZ26889.1 - 0.014 15.4 0.0 9.1 6.4 0.0 3.2 2 1 1 3 3 3 0 Ciliary BBSome complex subunit 2, middle region DUF2974 PF11187.8 CBZ26889.1 - 0.044 13.3 0.2 0.081 12.5 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) WD40_like PF17005.5 CBZ26889.1 - 0.071 12.4 0.0 0.88 8.8 0.0 2.1 2 0 0 2 2 2 0 WD40-like domain DivIC PF04977.15 CBZ26889.1 - 0.13 12.0 2.0 0.27 11.0 2.0 1.5 1 0 0 1 1 1 0 Septum formation initiator PQQ_3 PF13570.6 CBZ26889.1 - 0.13 12.7 0.1 0.13 12.7 0.1 5.9 7 0 0 7 7 7 0 PQQ-like domain WD40 PF00400.32 CBZ26890.1 - 9.5e-11 42.1 12.5 8.3e-07 29.6 0.1 5.1 6 0 0 6 6 6 2 WD domain, G-beta repeat Orthopox_A5L PF06193.11 CBZ26890.1 - 0.07 12.6 0.1 0.07 12.6 0.1 2.9 3 0 0 3 3 3 0 Orthopoxvirus A5L protein-like RAB3GAP2_N PF14655.6 CBZ26890.1 - 0.1 11.8 0.0 0.32 10.2 0.0 1.8 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus PQQ_3 PF13570.6 CBZ26890.1 - 0.16 12.5 0.0 23 5.6 0.1 3.8 4 0 0 4 4 4 0 PQQ-like domain ADK PF00406.22 CBZ26891.1 - 4.5e-39 134.0 0.0 6.8e-39 133.4 0.0 1.2 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 CBZ26891.1 - 3.6e-17 63.0 0.0 8.7e-17 61.8 0.0 1.6 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 CBZ26891.1 - 4.6e-05 24.0 0.0 0.00076 20.0 0.0 2.5 2 1 0 2 2 2 1 AAA domain AAA_33 PF13671.6 CBZ26891.1 - 0.048 13.8 0.1 0.16 12.1 0.0 1.9 2 1 0 2 2 2 0 AAA domain Hydin_ADK PF17213.3 CBZ26891.1 - 0.34 11.2 0.9 11 6.3 0.4 2.1 2 0 0 2 2 2 0 Hydin Adenylate kinase-like domain LRR_6 PF13516.6 CBZ26892.1 - 1.6e-06 27.7 1.2 1.6 9.0 0.2 3.5 3 0 0 3 3 3 3 Leucine Rich repeat LRR_4 PF12799.7 CBZ26892.1 - 0.069 13.6 0.2 1.1 9.8 0.1 2.3 2 0 0 2 2 2 0 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CBZ26892.1 - 0.37 10.6 1.8 12 5.8 1.0 2.8 2 1 0 2 2 2 0 Leucine rich repeat Serine_rich PF08824.10 CBZ26893.1 - 0.0024 17.9 0.0 0.013 15.5 0.0 2.1 2 0 0 2 2 2 1 Serine rich protein interaction domain SelR PF01641.18 CBZ26894.1 - 0.0011 19.0 0.0 0.37 10.9 0.0 2.5 2 1 0 2 2 2 2 SelR domain Synaptobrevin PF00957.21 CBZ26895.1 - 1.6e-25 88.7 0.5 2.6e-25 88.0 0.5 1.3 1 0 0 1 1 1 1 Synaptobrevin zf-RING_2 PF13639.6 CBZ26896.1 - 4.7e-10 39.6 3.6 8.3e-08 32.4 1.4 2.4 2 0 0 2 2 2 2 Ring finger domain zf-C3HC4_2 PF13923.6 CBZ26896.1 - 8.4e-09 35.1 2.8 4.1e-07 29.7 0.9 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 CBZ26896.1 - 2.7e-08 34.0 2.4 2.3e-07 31.0 1.0 2.3 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 CBZ26896.1 - 4.7e-07 29.6 2.4 4e-06 26.6 0.7 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 CBZ26896.1 - 6.8e-07 28.9 0.6 0.0028 17.4 0.1 2.5 2 0 0 2 2 2 2 RING-like zinc finger zf-ANAPC11 PF12861.7 CBZ26896.1 - 0.00017 21.5 0.2 0.00033 20.6 0.2 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.6 CBZ26896.1 - 0.016 15.1 3.2 0.048 13.5 0.7 2.2 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CBZ26896.1 - 0.028 14.4 8.8 0.18 11.9 1.8 3.0 2 1 1 3 3 3 0 RING-type zinc-finger zf-RING_5 PF14634.6 CBZ26896.1 - 0.087 12.8 1.6 0.4 10.7 0.6 2.2 2 0 0 2 2 2 0 zinc-RING finger domain zf-RING-like PF08746.11 CBZ26896.1 - 0.32 11.3 1.3 0.84 10.0 1.3 1.7 1 0 0 1 1 1 0 RING-like domain zf-RING_4 PF14570.6 CBZ26896.1 - 0.71 9.7 2.9 0.33 10.8 0.4 1.8 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain Zn_ribbon_17 PF17120.5 CBZ26896.1 - 0.86 9.3 3.0 0.75 9.5 0.9 1.8 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type zf-C3HC4_4 PF15227.6 CBZ26896.1 - 1.5 9.0 5.8 0.38 11.0 1.1 2.1 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING RF-1 PF00472.20 CBZ26897.1 - 4.7e-09 36.2 0.9 4.7e-09 36.2 0.9 3.8 4 1 0 4 4 4 1 RF-1 domain KASH_CCD PF14662.6 CBZ26897.1 - 0.0011 18.9 10.1 0.0011 18.9 10.1 2.9 3 1 0 3 3 3 1 Coiled-coil region of CCDC155 or KASH DUF4250 PF14056.6 CBZ26897.1 - 0.061 13.3 4.2 0.13 12.3 0.7 3.2 2 1 1 3 3 3 0 Domain of unknown function (DUF4250) Lectin_N PF03954.14 CBZ26897.1 - 0.34 10.7 7.6 3.1 7.5 1.4 3.4 2 1 1 3 3 3 0 Hepatic lectin, N-terminal domain IL6 PF00489.17 CBZ26897.1 - 1.2 8.7 5.0 0.64 9.6 0.7 2.4 2 1 0 2 2 2 0 Interleukin-6/G-CSF/MGF family Laminin_II PF06009.12 CBZ26897.1 - 2.3 8.3 14.1 0.48 10.4 7.1 3.1 2 1 1 3 3 3 0 Laminin Domain II PKcGMP_CC PF16808.5 CBZ26897.1 - 4.7 7.1 7.2 0.92 9.4 1.9 2.6 3 0 0 3 3 3 0 Coiled-coil N-terminus of cGMP-dependent protein kinase SMC_N PF02463.19 CBZ26900.1 - 1.9e-70 236.7 9.9 3.1e-69 232.8 9.9 3.1 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 CBZ26900.1 - 1.2e-19 70.7 0.0 4.3e-19 68.9 0.0 2.1 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.6 CBZ26900.1 - 1.8e-12 47.7 0.8 3.4e-05 23.8 0.1 2.7 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 CBZ26900.1 - 1.7e-05 24.4 0.0 3.3e-05 23.5 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_23 PF13476.6 CBZ26900.1 - 2.8e-05 24.7 16.9 2.8e-05 24.7 16.9 5.8 2 2 2 4 4 1 1 AAA domain AAA_15 PF13175.6 CBZ26900.1 - 6.5e-05 22.8 9.8 6.5e-05 22.8 9.8 3.9 2 2 0 2 2 1 1 AAA ATPase domain TIM21 PF08294.11 CBZ26900.1 - 0.087 12.7 1.0 0.3 10.9 1.0 1.9 1 0 0 1 1 1 0 TIM21 ABC_tran PF00005.27 CBZ26900.1 - 0.11 13.0 0.0 0.11 13.0 0.0 4.9 4 2 0 5 5 4 0 ABC transporter CARD PF00619.21 CBZ26900.1 - 0.93 9.6 0.0 0.93 9.6 0.0 4.2 4 1 1 5 5 5 0 Caspase recruitment domain AAA_22 PF13401.6 CBZ26900.1 - 1.2 9.5 0.0 1.2 9.5 0.0 4.9 4 2 2 6 6 6 0 AAA domain Lipoprotein_6 PF01441.19 CBZ26900.1 - 6 6.8 12.7 0.29 11.1 1.7 3.3 2 0 0 2 2 2 0 Lipoprotein V-ATPase_H_N PF03224.14 CBZ26901.1 - 7.9e-72 242.2 0.2 1.1e-71 241.7 0.2 1.2 1 0 0 1 1 1 1 V-ATPase subunit H V-ATPase_H_C PF11698.8 CBZ26901.1 - 6e-36 123.1 0.0 3.4e-35 120.7 0.0 2.1 2 0 0 2 2 2 1 V-ATPase subunit H RACo_linker PF17650.1 CBZ26901.1 - 0.055 13.3 0.2 0.26 11.2 0.0 2.2 2 0 0 2 2 2 0 RACo linker region PB1 PF00564.24 CBZ26902.1 - 1.1e-08 34.8 0.0 3.4e-08 33.3 0.0 1.8 1 0 0 1 1 1 1 PB1 domain DUF5433 PF17498.2 CBZ26904.1 - 1.1 9.5 2.8 2.8 8.2 2.8 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5433) DHHC PF01529.20 CBZ26906.1 - 1.1e-30 106.5 3.0 1.1e-30 106.5 3.0 2.1 2 1 0 2 2 2 1 DHHC palmitoyltransferase Herpes_UL73 PF03554.13 CBZ26906.1 - 0.14 12.1 1.2 0.43 10.6 1.2 1.9 1 0 0 1 1 1 0 UL73 viral envelope glycoprotein DUF971 PF06155.12 CBZ26907.1 - 2.4e-14 53.7 0.0 5.8e-13 49.3 0.0 2.9 3 0 0 3 3 3 1 Protein of unknown function (DUF971) DUF393 PF04134.12 CBZ26908.1 - 0.00068 21.0 2.2 0.036 15.4 0.4 2.6 2 1 0 2 2 2 2 Protein of unknown function, DUF393 Toxin_22 PF08092.11 CBZ26908.1 - 0.038 14.0 2.7 0.085 12.9 1.8 2.0 2 0 0 2 2 2 0 Magi peptide toxin family E1_dh PF00676.20 CBZ26909.1 - 1.1e-78 264.2 0.0 1.6e-78 263.7 0.0 1.1 1 0 0 1 1 1 1 Dehydrogenase E1 component EcsC PF12787.7 CBZ26909.1 - 0.19 11.4 0.5 0.36 10.5 0.1 1.6 2 0 0 2 2 2 0 EcsC protein family Cyt-b5 PF00173.28 CBZ26910.1 - 4.4e-05 23.5 0.0 0.00016 21.7 0.0 1.9 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Rad60-SLD PF11976.8 CBZ26910.1 - 0.009 15.8 0.0 0.055 13.3 0.0 2.2 2 1 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like PRMT5 PF05185.16 CBZ26911.1 - 6.1e-40 136.9 0.0 1e-39 136.1 0.0 1.3 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase PRMT5_C PF17286.2 CBZ26911.1 - 5.3e-22 78.5 0.0 7.9e-22 78.0 0.0 1.3 1 0 0 1 1 1 1 PRMT5 oligomerisation domain TPR_2 PF07719.17 CBZ26913.1 - 0.00032 20.6 3.1 0.023 14.8 1.1 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat MIT PF04212.18 CBZ26913.1 - 0.0011 19.0 1.4 0.011 15.8 0.0 2.6 2 0 0 2 2 2 1 MIT (microtubule interacting and transport) domain TPR_8 PF13181.6 CBZ26913.1 - 0.0014 18.7 3.0 2 8.8 1.0 4.1 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_12 PF13424.6 CBZ26913.1 - 0.0047 17.2 6.7 0.59 10.5 2.6 3.7 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_10 PF13374.6 CBZ26913.1 - 0.0055 16.5 3.9 2.5 8.1 1.1 3.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.28 CBZ26913.1 - 0.041 13.7 5.1 0.46 10.4 2.8 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat CCB1 PF12046.8 CBZ26913.1 - 0.092 12.1 0.0 0.16 11.3 0.0 1.3 1 0 0 1 1 1 0 Cofactor assembly of complex C subunit B TPR_6 PF13174.6 CBZ26913.1 - 1.6 9.5 5.3 23 5.9 0.7 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.6 CBZ26913.1 - 2.4 9.2 5.3 18 6.5 0.7 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat MAM33 PF02330.16 CBZ26914.1 - 0.02 14.8 0.5 0.04 13.9 0.5 1.4 1 0 0 1 1 1 0 Mitochondrial glycoprotein HMG_box PF00505.19 CBZ26918.1 - 6.7e-08 32.8 2.4 0.018 15.4 0.1 4.1 3 1 1 4 4 4 2 HMG (high mobility group) box HMG_box_2 PF09011.10 CBZ26918.1 - 4.3e-07 30.4 4.1 0.038 14.6 0.7 3.5 3 1 0 3 3 3 2 HMG-box domain HMG_box_5 PF14887.6 CBZ26918.1 - 0.11 12.5 0.2 1.9 8.5 0.1 2.6 3 0 0 3 3 3 0 HMG (high mobility group) box 5 DUF647 PF04884.14 CBZ26919.1 - 5.8e-71 238.9 0.6 8.6e-71 238.4 0.6 1.2 1 0 0 1 1 1 1 Vitamin B6 photo-protection and homoeostasis Sec8_exocyst PF04048.14 CBZ26920.1 - 3.6e-11 43.1 0.3 9e-11 41.8 0.3 1.6 1 0 0 1 1 1 1 Sec8 exocyst complex component specific domain Zw10 PF06248.13 CBZ26920.1 - 9.5e-05 21.2 0.6 0.00018 20.2 0.6 1.4 1 0 0 1 1 1 1 Centromere/kinetochore Zw10 Vps54_N PF10475.9 CBZ26920.1 - 0.00093 18.6 0.2 0.0017 17.7 0.2 1.3 1 0 0 1 1 1 1 Vacuolar-sorting protein 54, of GARP complex Na_trans_assoc PF06512.13 CBZ26920.1 - 0.81 9.9 4.7 1.8 8.8 4.7 1.5 1 0 0 1 1 1 0 Sodium ion transport-associated Ribosomal_S17 PF00366.20 CBZ26921.1 - 2.7e-23 81.8 0.3 5.1e-23 81.0 0.3 1.5 1 0 0 1 1 1 1 Ribosomal protein S17 Ribosomal_S17_N PF16205.5 CBZ26921.1 - 1.1e-21 77.0 1.5 1.1e-21 77.0 0.1 1.7 2 0 0 2 2 2 1 Ribosomal_S17 N-terminal DUF2232 PF09991.9 CBZ26922.1 - 0.0034 16.6 0.2 0.0068 15.6 0.2 1.4 1 0 0 1 1 1 1 Predicted membrane protein (DUF2232) DUF4018 PF13210.6 CBZ26922.1 - 0.013 15.3 0.4 0.021 14.6 0.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4018) DEAD PF00270.29 CBZ26923.1 - 2.5e-36 125.1 0.2 1.8e-35 122.3 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CBZ26923.1 - 9.9e-26 90.3 0.9 3e-25 88.7 0.2 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 CBZ26923.1 - 9.5e-09 35.5 0.0 1.8e-08 34.6 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CMS1 PF14617.6 CBZ26923.1 - 0.0034 16.8 2.9 0.0058 16.0 0.0 2.7 4 1 1 5 5 5 1 U3-containing 90S pre-ribosomal complex subunit DUF4844 PF16133.5 CBZ26923.1 - 0.009 16.6 1.2 0.028 15.0 0.6 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4844) LETM1 PF07766.13 CBZ26924.1 - 0.00016 21.1 0.1 0.00055 19.4 0.0 1.8 2 1 0 2 2 2 1 LETM1-like protein Tn7_Tnp_TnsA_N PF08722.11 CBZ26924.1 - 0.011 15.9 0.1 0.025 14.8 0.1 1.5 1 0 0 1 1 1 0 TnsA endonuclease N terminal GST_C_6 PF17171.4 CBZ26925.1 - 1.6e-06 27.8 0.0 5.1e-06 26.2 0.0 1.9 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain DUF2537 PF10801.8 CBZ26925.1 - 0.78 10.0 6.0 0.14 12.4 1.1 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2537) COG6 PF06419.11 CBZ26926.1 - 0.06 11.6 0.0 0.083 11.1 0.0 1.1 1 0 0 1 1 1 0 Conserved oligomeric complex COG6 GMC_oxred_C PF05199.13 CBZ26927.1 - 6.6e-13 49.4 0.1 5.3e-12 46.5 0.0 2.4 2 1 0 2 2 2 1 GMC oxidoreductase GMC_oxred_N PF00732.19 CBZ26927.1 - 5.1e-12 45.8 0.0 7.1e-12 45.3 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.12 CBZ26927.1 - 0.00024 20.3 0.0 0.013 14.6 0.1 2.7 3 0 0 3 3 3 1 Lycopene cyclase protein Pyr_redox_2 PF07992.14 CBZ26927.1 - 0.00075 18.8 0.2 0.079 12.2 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 CBZ26927.1 - 0.0031 16.3 0.3 0.0046 15.7 0.3 1.2 1 0 0 1 1 1 1 HI0933-like protein NAD_binding_8 PF13450.6 CBZ26927.1 - 0.0032 17.7 5.0 0.0036 17.5 0.3 3.2 4 0 0 4 4 4 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 CBZ26927.1 - 0.0053 15.9 0.1 0.012 14.7 0.1 1.6 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 CBZ26927.1 - 0.0064 16.1 0.6 0.11 12.0 0.1 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.17 CBZ26927.1 - 0.031 13.5 0.6 0.031 13.5 0.6 2.0 3 0 0 3 3 3 0 Thi4 family Pkinase PF00069.25 CBZ26928.1 - 2.3e-63 214.0 0.0 4.1e-63 213.2 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ26928.1 - 2e-44 151.8 0.0 3.4e-44 151.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CBZ26928.1 - 6e-05 22.5 0.0 6e-05 22.5 0.0 1.8 2 0 0 2 2 2 1 Kinase-like RIO1 PF01163.22 CBZ26928.1 - 0.029 14.0 0.0 0.029 14.0 0.0 2.3 2 1 0 2 2 2 0 RIO1 family Pkinase_fungal PF17667.1 CBZ26928.1 - 0.24 10.1 0.0 0.24 10.1 0.0 3.3 3 1 0 3 3 3 0 Fungal protein kinase MIP-T3_C PF17749.1 CBZ26929.1 - 2e-53 180.5 2.3 2e-53 180.5 2.3 3.0 2 1 0 2 2 2 1 Microtubule-binding protein MIP-T3 C-terminal region MIP-T3 PF10243.9 CBZ26929.1 - 1.5e-48 163.4 0.4 5.1e-48 161.8 0.1 2.0 2 0 0 2 2 2 1 Microtubule-binding protein MIP-T3 CH-like domain DUF5082 PF16888.5 CBZ26929.1 - 0.007 16.6 2.1 0.022 15.0 2.1 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF5082) UPF0242 PF06785.11 CBZ26929.1 - 0.42 10.7 12.2 0.043 13.9 0.8 2.4 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus COMP PF11598.8 CBZ26929.1 - 1.7 9.2 5.8 1.2 9.7 1.4 2.5 2 1 0 2 2 2 0 Cartilage oligomeric matrix protein CK2S PF15011.6 CBZ26930.1 - 0.089 12.7 0.0 0.12 12.3 0.0 1.2 1 0 0 1 1 1 0 Casein Kinase 2 substrate peroxidase PF00141.23 CBZ26931.1 - 2.1e-09 37.4 0.0 1.1e-08 35.1 0.0 2.0 1 1 0 2 2 2 1 Peroxidase ANAPC4_WD40 PF12894.7 CBZ26932.1 - 0.073 13.4 0.2 1 9.7 0.0 2.9 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 CBZ26932.1 - 0.096 13.6 9.5 2.7 9.0 0.1 5.2 4 1 0 4 4 4 0 WD domain, G-beta repeat Chordopox_A13L PF05961.11 CBZ26933.1 - 0.087 13.1 0.2 0.42 10.9 0.2 2.3 1 0 0 1 1 1 0 Chordopoxvirus A13L protein Nodulin-like PF06813.13 CBZ26934.1 - 0.00046 19.7 9.2 0.00046 19.7 9.2 2.8 3 1 0 3 3 3 1 Nodulin-like MFS_1 PF07690.16 CBZ26934.1 - 0.32 9.8 58.6 0.0084 15.1 32.1 3.2 2 1 0 2 2 2 0 Major Facilitator Superfamily F-box-like PF12937.7 CBZ26935.1 - 1.2e-06 28.3 0.6 2.8e-06 27.1 0.6 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 CBZ26935.1 - 1.9e-06 27.6 1.2 5.4e-06 26.1 0.8 2.0 2 0 0 2 2 2 1 F-box domain TrbI_Ftype PF09677.10 CBZ26936.1 - 0.068 13.5 0.0 0.15 12.4 0.0 1.6 1 0 0 1 1 1 0 Type-F conjugative transfer system protein (TrbI_Ftype) FapA PF03961.13 CBZ26936.1 - 0.82 8.2 3.4 0.54 8.8 1.7 1.6 1 1 1 2 2 2 0 Flagellar Assembly Protein A V_ATPase_I PF01496.19 CBZ26936.1 - 1.1 7.1 3.6 1.9 6.3 3.5 1.4 1 1 1 2 2 2 0 V-type ATPase 116kDa subunit family DivIC PF04977.15 CBZ26936.1 - 1.4 8.8 4.4 20 5.1 3.4 2.8 3 1 0 3 3 3 0 Septum formation initiator DUF3782 PF12644.7 CBZ26936.1 - 1.4 9.2 4.1 44 4.3 0.0 3.3 3 1 0 3 3 3 0 Protein of unknown function (DUF3782) zf-Sec23_Sec24 PF04810.15 CBZ26937.1 - 0.02 14.9 0.0 0.02 14.9 0.0 2.1 2 0 0 2 2 2 0 Sec23/Sec24 zinc finger Vps36-NZF-N PF16988.5 CBZ26937.1 - 5.6 6.4 8.4 18 4.8 8.4 1.9 1 1 0 1 1 1 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain Rad60-SLD_2 PF13881.6 CBZ26938.1 - 1.1e-06 28.7 1.4 1.6e-05 24.9 1.4 2.3 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 CBZ26938.1 - 0.00035 21.1 0.0 0.00058 20.4 0.0 1.5 1 1 0 1 1 1 1 DUF2407 ubiquitin-like domain PPR_2 PF13041.6 CBZ26939.1 - 1.1e-08 35.1 0.3 2.9e-08 33.8 0.1 1.8 2 0 0 2 2 2 1 PPR repeat family PPR_3 PF13812.6 CBZ26939.1 - 4.1e-06 26.8 0.1 8.1e-06 25.8 0.1 1.4 1 0 0 1 1 1 1 Pentatricopeptide repeat domain PPR PF01535.20 CBZ26939.1 - 6.3e-05 23.0 0.2 0.00026 21.0 0.1 2.1 2 0 0 2 2 2 1 PPR repeat PPR_long PF17177.4 CBZ26939.1 - 0.048 13.0 0.1 0.071 12.5 0.1 1.2 1 0 0 1 1 1 0 Pentacotripeptide-repeat region of PRORP EF-hand_1 PF00036.32 CBZ26940.1 - 7.4e-24 81.5 6.9 1.7e-06 27.1 0.3 4.4 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 CBZ26940.1 - 1.3e-22 80.1 2.8 7.4e-13 48.8 1.3 3.1 3 0 0 3 3 3 3 EF-hand domain pair EF-hand_6 PF13405.6 CBZ26940.1 - 3.1e-19 67.2 6.8 0.00013 21.6 0.3 4.6 5 0 0 5 5 5 4 EF-hand domain EF-hand_5 PF13202.6 CBZ26940.1 - 2.8e-15 55.0 12.9 1.3e-06 27.6 0.2 4.7 5 0 0 5 5 5 3 EF hand EF-hand_8 PF13833.6 CBZ26940.1 - 3e-10 39.8 6.5 0.0012 18.7 1.1 4.1 3 1 1 4 4 4 4 EF-hand domain pair EF-hand_4 PF12763.7 CBZ26940.1 - 8.4e-08 32.1 2.2 0.055 13.4 0.2 3.5 1 1 2 3 3 3 3 Cytoskeletal-regulatory complex EF hand Dockerin_1 PF00404.18 CBZ26940.1 - 3.7e-06 27.0 1.2 0.00081 19.5 0.8 2.7 2 1 0 2 2 2 1 Dockerin type I domain SPARC_Ca_bdg PF10591.9 CBZ26940.1 - 9e-06 26.0 0.0 0.021 15.1 0.0 2.4 2 1 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region DUF1425 PF07233.12 CBZ26940.1 - 0.1 12.5 0.0 0.2 11.6 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1425) TetR_C_31 PF17940.1 CBZ26941.1 - 0.047 13.9 0.1 0.15 12.3 0.0 1.9 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain EF-hand_8 PF13833.6 CBZ26941.1 - 0.15 12.0 0.0 7 6.6 0.0 2.3 2 0 0 2 2 2 0 EF-hand domain pair Pkinase PF00069.25 CBZ26942.1 - 7.5e-41 140.2 0.0 9.4e-41 139.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ26942.1 - 3.9e-10 39.4 0.0 6.6e-10 38.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase 5_3_exonuc_N PF02739.16 CBZ26943.1 - 1.2e-26 93.5 0.1 1.9e-26 92.9 0.1 1.3 1 0 0 1 1 1 1 5'-3' exonuclease, N-terminal resolvase-like domain 5_3_exonuc PF01367.20 CBZ26943.1 - 1.5e-19 70.3 0.0 3.2e-19 69.3 0.0 1.5 1 0 0 1 1 1 1 5'-3' exonuclease, C-terminal SAM fold EspB_PE PF18625.1 CBZ26943.1 - 0.0091 16.4 0.0 0.023 15.2 0.0 1.6 1 0 0 1 1 1 1 ESX-1 secreted protein B PE domain DUF3361 PF11841.8 CBZ26944.1 - 0.042 13.8 0.1 0.19 11.6 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3361) zf-MYND PF01753.18 CBZ26945.1 - 0.002 18.2 20.3 0.0034 17.4 20.3 1.4 1 0 0 1 1 1 1 MYND finger PolC_DP2 PF03833.13 CBZ26945.1 - 0.4 8.5 1.7 0.41 8.4 1.7 1.0 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 PUF PF00806.19 CBZ26946.1 - 2.3e-48 159.2 4.0 1e-05 24.9 0.1 8.3 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat HrpB1_HrpK PF09613.10 CBZ26946.1 - 0.0022 17.7 0.1 0.51 10.0 0.0 3.1 3 0 0 3 3 3 1 Bacterial type III secretion protein (HrpB1_HrpK) DEP PF00610.21 CBZ26946.1 - 0.054 13.6 0.1 0.18 11.9 0.1 1.9 2 0 0 2 2 2 0 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) MCU PF04678.13 CBZ26947.1 - 2.6e-31 109.1 0.6 4.3e-31 108.4 0.3 1.4 1 1 0 1 1 1 1 Mitochondrial calcium uniporter Proteasome PF00227.26 CBZ26948.1 - 1.6e-64 216.9 0.0 2.3e-64 216.4 0.0 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 CBZ26948.1 - 6.4e-09 35.3 0.6 3.6e-08 32.9 0.1 2.2 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature YadA_head PF05658.14 CBZ26948.1 - 0.23 11.9 6.0 0.95 9.9 1.2 2.3 2 0 0 2 2 2 0 Head domain of trimeric autotransporter adhesin DUF4874 PF16173.5 CBZ26949.1 - 0.098 12.3 0.3 0.13 11.9 0.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4874) Ribosomal_L32e PF01655.18 CBZ26950.1 - 1.8e-39 134.5 0.2 2.2e-39 134.2 0.2 1.1 1 0 0 1 1 1 1 Ribosomal protein L32 Ribosomal_L6e PF01159.19 CBZ26951.1 - 0.13 12.8 0.2 0.13 12.8 0.2 2.3 1 1 1 2 2 2 0 Ribosomal protein L6e TipAS PF07739.13 CBZ26951.1 - 0.8 10.3 9.4 5.6 7.5 5.5 2.3 2 1 0 2 2 2 0 TipAS antibiotic-recognition domain Wbp11 PF09429.10 CBZ26951.1 - 1.2 9.6 19.0 0.2 12.1 13.1 2.2 2 0 0 2 2 2 0 WW domain binding protein 11 PEHE PF15275.6 CBZ26951.1 - 2 9.0 8.2 1.3 9.6 6.2 1.7 1 1 1 2 2 2 0 PEHE domain PAP_assoc PF03828.19 CBZ26952.1 - 0.0004 20.5 0.8 0.0012 19.0 0.8 1.8 1 1 0 1 1 1 1 Cid1 family poly A polymerase SET PF00856.28 CBZ26953.1 - 6.7e-06 26.6 0.4 0.00042 20.7 0.4 2.4 1 1 0 1 1 1 1 SET domain DUF2786 PF10979.8 CBZ26953.1 - 0.0064 16.4 0.1 0.012 15.6 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2786) PHD PF00628.29 CBZ26953.1 - 0.15 12.0 10.4 0.56 10.1 10.4 2.1 1 1 0 1 1 1 0 PHD-finger FYVE PF01363.21 CBZ26953.1 - 0.16 12.1 8.3 0.51 10.5 8.3 1.8 1 0 0 1 1 1 0 FYVE zinc finger DKCLD PF08068.12 CBZ26954.1 - 1.2e-31 108.5 0.0 2e-30 104.6 0.1 2.5 2 0 0 2 2 2 1 DKCLD (NUC011) domain TruB_N PF01509.18 CBZ26954.1 - 4.3e-22 79.1 2.5 2.5e-15 57.1 0.5 3.3 1 1 1 2 2 2 2 TruB family pseudouridylate synthase (N terminal domain) PUA PF01472.20 CBZ26954.1 - 1.3e-20 73.1 0.9 2.7e-20 72.1 0.9 1.5 1 0 0 1 1 1 1 PUA domain TruB_C_2 PF16198.5 CBZ26954.1 - 2.3e-20 72.5 0.3 4.3e-20 71.6 0.3 1.5 1 0 0 1 1 1 1 tRNA pseudouridylate synthase B C-terminal domain UPF0113 PF03657.13 CBZ26954.1 - 0.0086 16.3 0.0 0.033 14.4 0.0 2.0 2 0 0 2 2 2 1 UPF0113 PUA domain ATP-synt PF00231.19 CBZ26955.1 - 2e-50 172.1 1.4 2.2e-50 171.9 1.4 1.0 1 0 0 1 1 1 1 ATP synthase Ribosomal_S6e PF01092.19 CBZ26956.1 - 9.4e-39 132.2 0.0 1.9e-38 131.2 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein S6e RdRP_3 PF00998.23 CBZ26956.1 - 0.056 12.1 6.0 0.067 11.9 6.0 1.1 1 0 0 1 1 1 0 Viral RNA dependent RNA polymerase WSK PF03832.13 CBZ26956.1 - 0.092 12.5 0.3 0.092 12.5 0.3 2.2 2 0 0 2 2 2 0 WSK motif ATP-synt_C PF00137.21 CBZ26957.1 - 9.1e-27 93.2 34.1 3.2e-19 69.0 14.6 2.6 3 0 0 3 3 3 2 ATP synthase subunit C GerA PF03323.13 CBZ26957.1 - 0.18 10.2 2.7 2.8 6.3 0.3 2.1 2 0 0 2 2 2 0 Bacillus/Clostridium GerA spore germination protein TctB PF07331.11 CBZ26957.1 - 3.7 7.8 13.3 19 5.6 13.3 2.1 1 1 0 1 1 1 0 Tripartite tricarboxylate transporter TctB family Goodbye PF17109.5 CBZ26957.1 - 5.7 7.4 5.4 1.5 9.3 1.2 1.9 2 0 0 2 2 2 0 fungal STAND N-terminal Goodbye domain ATP-synt_C PF00137.21 CBZ26958.1 - 9.1e-27 93.2 34.1 3.2e-19 69.0 14.6 2.6 3 0 0 3 3 3 2 ATP synthase subunit C GerA PF03323.13 CBZ26958.1 - 0.18 10.2 2.7 2.8 6.3 0.3 2.1 2 0 0 2 2 2 0 Bacillus/Clostridium GerA spore germination protein TctB PF07331.11 CBZ26958.1 - 3.7 7.8 13.3 19 5.6 13.3 2.1 1 1 0 1 1 1 0 Tripartite tricarboxylate transporter TctB family Goodbye PF17109.5 CBZ26958.1 - 5.7 7.4 5.4 1.5 9.3 1.2 1.9 2 0 0 2 2 2 0 fungal STAND N-terminal Goodbye domain Gaa1 PF04114.14 CBZ26959.1 - 1.8e-07 30.6 3.5 3.5e-07 29.6 0.1 2.3 1 1 1 2 2 2 1 Gaa1-like, GPI transamidase component Ribosomal_L37ae PF01780.19 CBZ26960.1 - 9.2e-37 125.0 4.5 1e-36 124.9 4.5 1.0 1 0 0 1 1 1 1 Ribosomal L37ae protein family C1_1 PF00130.22 CBZ26960.1 - 0.0022 17.8 2.3 0.0032 17.3 2.3 1.2 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-RING_13 PF17977.1 CBZ26960.1 - 0.05 13.7 1.1 0.071 13.2 1.1 1.2 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Zn_Tnp_IS1595 PF12760.7 CBZ26960.1 - 0.065 13.2 2.3 0.11 12.5 2.3 1.4 1 0 0 1 1 1 0 Transposase zinc-ribbon domain NOB1_Zn_bind PF08772.11 CBZ26960.1 - 0.16 12.2 3.8 0.43 10.8 0.6 2.3 1 1 1 2 2 2 0 Nin one binding (NOB1) Zn-ribbon like Proteasome PF00227.26 CBZ26961.1 - 2.1e-58 197.0 0.0 2.6e-58 196.6 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 CBZ26961.1 - 4.2e-13 48.7 0.0 1e-12 47.4 0.0 1.8 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Pex14_N PF04695.13 CBZ26962.1 - 3.9e-24 86.1 1.2 3.9e-24 86.1 1.2 4.1 2 1 2 4 4 4 1 Peroxisomal membrane anchor protein (Pex14p) conserved region Rootletin PF15035.6 CBZ26962.1 - 4.1e-07 30.2 0.1 6.1e-07 29.6 0.1 1.2 1 0 0 1 1 1 1 Ciliary rootlet component, centrosome cohesion APG6_N PF17675.1 CBZ26962.1 - 0.00029 21.4 0.3 0.00048 20.7 0.3 1.3 1 0 0 1 1 1 1 Apg6 coiled-coil region HOOK PF05622.12 CBZ26962.1 - 0.004 15.4 0.9 0.0051 15.0 0.9 1.0 1 0 0 1 1 1 1 HOOK protein LOH1CR12 PF10158.9 CBZ26962.1 - 0.0042 17.1 0.3 0.0069 16.4 0.3 1.2 1 0 0 1 1 1 1 Tumour suppressor protein GAS PF13851.6 CBZ26962.1 - 0.0059 16.0 5.0 0.0089 15.4 5.0 1.1 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding ERM PF00769.19 CBZ26962.1 - 0.0096 15.8 9.3 0.015 15.1 9.3 1.2 1 0 0 1 1 1 1 Ezrin/radixin/moesin family Siah-Interact_N PF09032.11 CBZ26962.1 - 0.015 15.6 5.7 2.3 8.6 0.2 3.0 1 1 1 2 2 2 0 Siah interacting protein, N terminal JAKMIP_CC3 PF16034.5 CBZ26962.1 - 0.017 15.1 1.3 0.03 14.3 1.3 1.3 1 0 0 1 1 1 0 JAKMIP CC3 domain KASH_CCD PF14662.6 CBZ26962.1 - 0.021 14.7 4.5 0.041 13.7 4.5 1.4 1 0 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH FAM76 PF16046.5 CBZ26962.1 - 0.025 14.0 0.1 0.035 13.4 0.1 1.2 1 0 0 1 1 1 0 FAM76 protein DUF1664 PF07889.12 CBZ26962.1 - 0.025 14.6 1.0 0.042 13.9 1.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) GIT_CC PF16559.5 CBZ26962.1 - 0.047 13.6 1.8 0.16 11.9 0.3 2.2 1 1 1 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor HMMR_N PF15905.5 CBZ26962.1 - 0.051 13.1 4.6 0.079 12.4 4.6 1.2 1 0 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal HAUS-augmin3 PF14932.6 CBZ26962.1 - 0.052 13.1 2.9 0.075 12.6 2.9 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 Macoilin PF09726.9 CBZ26962.1 - 0.053 12.1 0.1 0.073 11.6 0.1 1.1 1 0 0 1 1 1 0 Macoilin family CALCOCO1 PF07888.11 CBZ26962.1 - 0.073 11.9 5.1 0.1 11.4 5.1 1.1 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like FapA PF03961.13 CBZ26962.1 - 0.081 11.5 1.7 0.12 10.9 1.7 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A Rab5-bind PF09311.11 CBZ26962.1 - 0.097 12.0 3.3 0.18 11.2 3.3 1.4 1 0 0 1 1 1 0 Rabaptin-like protein GldM_N PF12081.8 CBZ26962.1 - 0.1 12.7 2.3 0.16 12.0 2.3 1.3 1 0 0 1 1 1 0 GldM N-terminal domain BLOC1_2 PF10046.9 CBZ26962.1 - 0.11 12.8 1.5 0.23 11.8 1.5 1.4 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Fez1 PF06818.15 CBZ26962.1 - 0.12 12.8 3.3 0.2 12.1 3.3 1.2 1 0 0 1 1 1 0 Fez1 AAA_13 PF13166.6 CBZ26962.1 - 0.15 10.7 0.3 0.21 10.2 0.3 1.1 1 0 0 1 1 1 0 AAA domain Flagellin_C PF00700.21 CBZ26962.1 - 0.2 12.0 1.0 0.5 10.8 0.6 1.7 1 1 0 1 1 1 0 Bacterial flagellin C-terminal helical region DUF5082 PF16888.5 CBZ26962.1 - 0.2 11.9 5.8 0.65 10.3 1.4 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF5082) CENP-H PF05837.12 CBZ26962.1 - 0.27 11.7 7.6 0.5 10.8 7.6 1.4 1 0 0 1 1 1 0 Centromere protein H (CENP-H) DUF2968 PF11180.8 CBZ26962.1 - 0.29 10.8 5.4 0.57 9.8 5.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) MbeD_MobD PF04899.12 CBZ26962.1 - 0.33 11.1 1.2 0.76 9.9 1.2 1.7 1 1 0 1 1 1 0 MbeD/MobD like Strumpellin PF10266.9 CBZ26962.1 - 0.39 8.4 1.0 0.52 8.0 1.0 1.0 1 0 0 1 1 1 0 Hereditary spastic paraplegia protein strumpellin PRKG1_interact PF15898.5 CBZ26962.1 - 0.61 11.0 5.5 1.5 9.7 5.5 1.6 1 0 0 1 1 1 0 cGMP-dependent protein kinase interacting domain ATG16 PF08614.11 CBZ26962.1 - 0.74 10.0 11.6 2.7 8.2 10.5 2.2 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) FlxA PF14282.6 CBZ26962.1 - 0.87 9.6 8.0 6.3 6.9 8.0 2.2 1 1 0 1 1 1 0 FlxA-like protein Spc7 PF08317.11 CBZ26962.1 - 0.93 8.3 6.8 1.4 7.7 6.8 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein CC2-LZ PF16516.5 CBZ26962.1 - 1 9.7 8.7 5.1 7.5 8.7 1.9 1 1 0 1 1 1 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator Atg14 PF10186.9 CBZ26962.1 - 1.1 8.3 4.5 1.7 7.7 4.5 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DivIC PF04977.15 CBZ26962.1 - 1.2 9.0 11.0 0.097 12.5 2.9 2.2 1 1 1 2 2 2 0 Septum formation initiator ZapB PF06005.12 CBZ26962.1 - 1.4 9.4 8.5 13 6.3 0.1 2.2 1 1 1 2 2 2 0 Cell division protein ZapB BRE1 PF08647.11 CBZ26962.1 - 1.4 9.0 8.4 0.97 9.5 1.0 2.2 1 1 1 2 2 2 0 BRE1 E3 ubiquitin ligase TMF_DNA_bd PF12329.8 CBZ26962.1 - 1.9 8.5 10.7 1.4 8.9 1.4 2.3 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding NuDC PF16273.5 CBZ26962.1 - 2 9.0 8.7 0.69 10.5 5.0 2.0 1 1 1 2 2 1 0 Nuclear distribution C domain Uso1_p115_C PF04871.13 CBZ26962.1 - 2.1 8.7 11.3 5.2 7.4 11.2 1.6 1 1 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region LPP PF04728.13 CBZ26962.1 - 2.2 8.7 10.0 1.7 9.1 1.2 2.9 1 1 1 2 2 2 0 Lipoprotein leucine-zipper TMCO5 PF14992.6 CBZ26962.1 - 2.4 7.7 5.7 4.6 6.7 5.7 1.4 1 1 0 1 1 1 0 TMCO5 family HALZ PF02183.18 CBZ26962.1 - 2.5 8.4 5.1 4 7.7 0.8 2.4 2 1 0 2 2 2 0 Homeobox associated leucine zipper SlyX PF04102.12 CBZ26962.1 - 2.7 8.7 5.0 5.1 7.8 0.8 2.5 1 1 1 2 2 2 0 SlyX TMF_TATA_bd PF12325.8 CBZ26962.1 - 2.8 8.2 7.0 24 5.2 0.1 2.0 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding RRF PF01765.19 CBZ26962.1 - 3.3 7.7 8.7 9.1 6.2 8.7 1.7 1 1 0 1 1 1 0 Ribosome recycling factor ADIP PF11559.8 CBZ26962.1 - 3.6 7.7 9.1 7.4 6.6 8.9 1.6 1 1 0 1 1 1 0 Afadin- and alpha -actinin-Binding Swi5 PF07061.11 CBZ26962.1 - 4.6 7.4 7.7 5.5e+02 0.7 7.5 3.0 2 1 0 2 2 2 0 Swi5 CENP-Q PF13094.6 CBZ26962.1 - 6.2 7.0 9.5 21 5.3 9.4 1.7 1 1 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit bZIP_1 PF00170.21 CBZ26962.1 - 6.9 6.8 10.0 1.5 9.0 0.9 2.5 2 1 1 3 3 2 0 bZIP transcription factor DUF4407 PF14362.6 CBZ26962.1 - 8.9 5.6 11.8 31 3.8 12.1 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) OmpH PF03938.14 CBZ26963.1 - 0.44 10.9 12.5 0.52 10.6 11.1 1.7 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) BolA PF01722.18 CBZ26964.1 - 5.2e-18 65.1 0.0 1.7e-17 63.5 0.0 1.7 1 1 0 1 1 1 1 BolA-like protein Tubulin PF00091.25 CBZ26965.1 - 6.1e-68 228.9 0.0 1e-67 228.2 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 CBZ26965.1 - 1.6e-41 141.4 0.1 2.3e-41 140.9 0.1 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 CBZ26965.1 - 4e-05 23.9 0.0 0.0001 22.6 0.0 1.7 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.6 CBZ26965.1 - 0.0054 16.4 0.0 0.01 15.5 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain Tubulin_2 PF13809.6 CBZ26965.1 - 0.057 12.6 0.2 0.2 10.8 0.0 1.8 2 0 0 2 2 2 0 Tubulin like Hist_deacetyl PF00850.19 CBZ26966.1 - 2e-77 260.7 0.2 4.6e-46 157.7 0.3 2.2 2 0 0 2 2 2 2 Histone deacetylase domain RAP1 PF07218.11 CBZ26966.1 - 1.5 7.0 3.8 2.1 6.5 3.8 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) SR-25 PF10500.9 CBZ26966.1 - 9.1 5.8 11.9 1.1 8.9 7.4 1.7 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein CLN3 PF02487.17 CBZ26967.1 - 4e-47 161.1 24.4 2.3e-46 158.6 24.4 2.0 1 1 0 1 1 1 1 CLN3 protein Cyt-b5 PF00173.28 CBZ26968.1 - 6.3e-07 29.5 0.0 6.6e-07 29.4 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain DUF1583 PF07622.11 CBZ26968.1 - 0.034 12.9 0.1 0.051 12.3 0.1 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1583) Gifsy-2 PF13856.6 CBZ26968.1 - 0.15 12.4 0.0 0.23 11.9 0.0 1.2 1 0 0 1 1 1 0 ATP-binding sugar transporter from pro-phage Ribosomal_L5_C PF00673.21 CBZ26970.1 - 8.2e-21 74.0 0.0 1.3e-20 73.3 0.0 1.3 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.19 CBZ26970.1 - 4.4e-18 65.4 0.2 1.1e-16 60.8 0.0 2.2 2 0 0 2 2 2 1 Ribosomal protein L5 SET PF00856.28 CBZ26971.1 - 2.8e-05 24.6 0.0 3.6e-05 24.2 0.0 1.2 1 0 0 1 1 1 1 SET domain XLF PF09302.11 CBZ26972.1 - 2.5 8.3 8.4 2.6 8.2 4.2 2.8 2 0 0 2 2 2 0 XLF-Cernunnos, XRcc4-like factor, NHEJ component DUF473 PF04322.12 CBZ26972.1 - 8.1 6.3 7.5 0.76 9.6 2.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF473) R3H PF01424.22 CBZ26973.1 - 4.3e-12 45.8 0.0 8.7e-12 44.9 0.0 1.5 1 0 0 1 1 1 1 R3H domain zf-NF-X1 PF01422.17 CBZ26973.1 - 1.6e-09 37.6 57.8 2.6e-05 24.2 14.4 14.8 15 1 1 16 16 16 8 NF-X1 type zinc finger HopA1 PF17914.1 CBZ26973.1 - 0.014 15.1 0.1 3.2 7.5 0.0 2.5 1 1 0 2 2 2 0 HopA1 effector protein family Rad10 PF03834.14 CBZ26974.1 - 0.00015 21.7 0.0 0.00022 21.2 0.0 1.2 1 0 0 1 1 1 1 Binding domain of DNA repair protein Ercc1 (rad10/Swi10) DnaJ_C PF01556.18 CBZ26975.1 - 8.1e-35 120.1 0.0 1e-34 119.8 0.0 1.1 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.19 CBZ26975.1 - 1.1e-13 51.3 15.2 1.3e-13 51.1 14.1 1.8 2 0 0 2 2 2 1 DnaJ central domain Anti-TRAP PF15777.5 CBZ26975.1 - 7.5e-06 25.8 13.2 0.011 15.7 5.0 2.4 1 1 1 2 2 2 2 Tryptophan RNA-binding attenuator protein inhibitory protein HypA PF01155.19 CBZ26975.1 - 0.0023 17.9 7.6 0.28 11.2 0.2 2.8 2 1 1 3 3 3 2 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Troponin PF00992.20 CBZ26975.1 - 0.29 11.4 2.2 0.51 10.6 2.2 1.3 1 0 0 1 1 1 0 Troponin TackOD1 PF18551.1 CBZ26975.1 - 0.39 10.4 3.0 0.75 9.4 3.0 1.4 1 1 0 1 1 1 0 Thaumarchaeal output domain 1 zinc-ribbons_6 PF07191.12 CBZ26975.1 - 0.91 9.5 6.9 26 4.9 0.4 2.5 1 1 1 2 2 2 0 zinc-ribbons FdhE PF04216.12 CBZ26975.1 - 2.4 8.0 5.3 4.3 7.1 5.3 1.5 1 0 0 1 1 1 0 Protein involved in formate dehydrogenase formation zf_CopZ PF18423.1 CBZ26975.1 - 3.6 7.6 5.7 7.3 6.6 0.1 3.2 3 0 0 3 3 3 0 Zinc binding domain Zn-ribbon_8 PF09723.10 CBZ26975.1 - 7.4 6.8 10.6 10 6.3 0.2 3.9 3 0 0 3 3 3 0 Zinc ribbon domain Pox_MCEL PF03291.16 CBZ26976.1 - 1.9e-45 155.4 0.0 2.4e-45 155.1 0.0 1.1 1 0 0 1 1 1 1 mRNA capping enzyme mRNA_cap_C PF03919.15 CBZ26976.1 - 1.4e-08 35.4 0.0 3.4e-08 34.1 0.0 1.7 1 0 0 1 1 1 1 mRNA capping enzyme, C-terminal domain mRNA_cap_enzyme PF01331.19 CBZ26976.1 - 3.5e-07 30.2 0.0 0.027 14.3 0.0 2.5 2 1 0 2 2 2 2 mRNA capping enzyme, catalytic domain Methyltransf_25 PF13649.6 CBZ26976.1 - 4.2e-06 27.4 0.2 0.00031 21.4 0.1 3.5 2 1 0 2 2 2 1 Methyltransferase domain NUP PF06516.11 CBZ26976.1 - 0.01 15.1 0.0 0.015 14.5 0.0 1.2 1 0 0 1 1 1 0 Purine nucleoside permease (NUP) GATase PF00117.28 CBZ26978.1 - 7.2e-39 133.5 0.0 1.6e-38 132.4 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase class-I GMP_synt_C PF00958.22 CBZ26978.1 - 7e-17 61.3 0.0 5.1e-09 36.1 0.0 3.0 2 1 0 2 2 2 2 GMP synthase C terminal domain Peptidase_C26 PF07722.13 CBZ26978.1 - 2e-14 53.9 0.0 1.6e-13 50.9 0.0 2.4 1 1 1 2 2 2 1 Peptidase C26 NAD_synthase PF02540.17 CBZ26978.1 - 5.2e-09 35.6 0.1 0.00022 20.5 0.1 2.4 2 0 0 2 2 2 2 NAD synthase QueC PF06508.13 CBZ26978.1 - 3.5e-05 23.4 0.0 0.00021 20.9 0.0 2.0 1 1 0 1 1 1 1 Queuosine biosynthesis protein QueC ThiI PF02568.14 CBZ26978.1 - 0.00052 19.7 0.2 0.0027 17.3 0.1 2.2 3 0 0 3 3 3 1 Thiamine biosynthesis protein (ThiI) Arginosuc_synth PF00764.19 CBZ26978.1 - 0.0016 17.8 0.0 0.0025 17.2 0.0 1.2 1 0 0 1 1 1 1 Arginosuccinate synthase PAPS_reduct PF01507.19 CBZ26978.1 - 0.0032 17.5 0.0 0.0055 16.8 0.0 1.5 1 1 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family GATase_3 PF07685.14 CBZ26978.1 - 0.0078 15.8 0.0 0.014 15.0 0.0 1.4 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain ATP_bind_3 PF01171.20 CBZ26978.1 - 0.0087 15.8 0.1 0.035 13.9 0.1 1.9 2 0 0 2 2 2 1 PP-loop family Asn_synthase PF00733.21 CBZ26978.1 - 0.011 15.4 0.2 0.021 14.5 0.2 1.3 1 0 0 1 1 1 0 Asparagine synthase tRNA_Me_trans PF03054.16 CBZ26978.1 - 0.017 14.0 0.1 0.062 12.1 0.1 1.8 2 0 0 2 2 2 0 tRNA methyl transferase GP79 PF17463.2 CBZ26978.1 - 0.13 12.3 0.3 0.33 11.0 0.3 1.6 1 0 0 1 1 1 0 Gene product 79 Tup_N PF08581.10 CBZ26979.1 - 0.00011 22.4 15.5 0.00088 19.5 0.9 3.2 2 1 1 3 3 3 2 Tup N-terminal Med20 PF08612.11 CBZ26979.1 - 0.043 13.2 1.3 0.064 12.6 0.5 1.5 1 1 0 1 1 1 0 TATA-binding related factor (TRF) of subunit 20 of Mediator complex FlaC_arch PF05377.11 CBZ26979.1 - 0.16 12.4 7.9 4.8 7.7 0.3 3.2 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) THOC7 PF05615.13 CBZ26979.1 - 0.25 11.6 30.2 0.087 13.1 14.3 2.2 1 1 0 2 2 2 0 Tho complex subunit 7 Golgin_A5 PF09787.9 CBZ26979.1 - 0.53 9.7 30.7 0.58 9.6 19.7 2.1 1 1 1 2 2 2 0 Golgin subfamily A member 5 DUF1664 PF07889.12 CBZ26979.1 - 0.71 9.9 14.2 0.054 13.5 6.1 2.7 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) DUF3584 PF12128.8 CBZ26979.1 - 0.73 7.3 32.8 0.88 7.0 32.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) NRN1 PF15056.6 CBZ26979.1 - 0.97 9.6 4.1 0.58 10.3 0.4 2.4 2 1 0 2 2 2 0 Neuritin protein family Bacillus_HBL PF05791.11 CBZ26979.1 - 2.1 8.2 9.9 0.79 9.5 3.6 2.3 2 1 0 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) Spc7 PF08317.11 CBZ26979.1 - 2.3 7.0 33.6 0.13 11.1 18.9 2.2 1 1 1 2 2 2 0 Spc7 kinetochore protein Arc_PepC_II PF06847.11 CBZ26979.1 - 2.8 8.5 5.1 54 4.4 5.1 2.6 1 1 0 1 1 1 0 Archaeal Peptidase A24 C-terminus Type II Csm1_N PF18504.1 CBZ26979.1 - 6 7.3 24.7 0.32 11.4 1.5 3.9 3 1 1 4 4 4 0 Csm1 N-terminal domain BAG PF02179.16 CBZ26981.1 - 5.7e-06 26.7 0.4 1.1e-05 25.8 0.4 1.3 1 0 0 1 1 1 1 BAG domain Dcc1 PF09724.9 CBZ26982.1 - 2e-52 178.6 0.0 2.3e-52 178.4 0.0 1.0 1 0 0 1 1 1 1 Sister chromatid cohesion protein Dcc1 zf-CCCH_4 PF18044.1 CBZ26983.1 - 3.5e-09 36.2 11.0 7.1e-05 22.5 2.5 3.1 2 0 0 2 2 2 2 CCCH-type zinc finger zf-CCCH PF00642.24 CBZ26983.1 - 2.6e-07 30.4 14.1 1.3e-05 25.0 1.8 3.1 3 0 0 3 3 3 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 CBZ26983.1 - 4.3e-05 23.4 20.3 0.0038 17.2 2.9 3.7 4 0 0 4 4 4 2 Zinc finger domain Torus PF16131.5 CBZ26983.1 - 7.7e-05 23.4 5.5 0.082 13.6 0.3 2.8 2 1 0 2 2 2 2 Torus domain DUF883 PF05957.13 CBZ26985.1 - 0.00053 20.5 15.6 0.021 15.4 6.9 3.4 1 1 2 3 3 3 3 Bacterial protein of unknown function (DUF883) Mitofilin PF09731.9 CBZ26985.1 - 0.0048 15.8 12.6 0.0054 15.7 12.6 1.2 1 0 0 1 1 1 1 Mitochondrial inner membrane protein ApoO PF09769.9 CBZ26985.1 - 0.0064 16.4 9.6 1.6 8.7 6.8 3.6 1 1 1 2 2 2 1 Apolipoprotein O Apolipoprotein PF01442.18 CBZ26985.1 - 0.0081 16.1 13.6 0.029 14.2 13.5 2.0 1 1 0 1 1 1 1 Apolipoprotein A1/A4/E domain ZYG-11_interact PF05884.12 CBZ26985.1 - 0.026 14.0 8.2 0.14 11.5 8.2 2.1 1 1 0 1 1 1 0 Interactor of ZYG-11 DUF357 PF04010.13 CBZ26985.1 - 0.065 13.3 1.1 14 5.8 0.1 3.1 1 1 2 3 3 3 0 Protein of unknown function (DUF357) BAR_3 PF16746.5 CBZ26985.1 - 0.23 11.1 3.3 0.43 10.2 3.3 1.5 1 0 0 1 1 1 0 BAR domain of APPL family TPR_MLP1_2 PF07926.12 CBZ26985.1 - 0.25 11.4 10.0 0.36 10.9 9.0 1.9 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein Filament PF00038.21 CBZ26985.1 - 0.35 10.4 6.1 2.5 7.6 0.3 2.2 1 1 1 2 2 2 0 Intermediate filament protein dUTPase_2 PF08761.11 CBZ26985.1 - 0.38 10.9 3.2 0.27 11.4 0.9 1.8 1 1 1 2 2 2 0 dUTPase dCache_2 PF08269.11 CBZ26985.1 - 0.49 9.5 7.8 0.2 10.8 2.7 2.2 1 1 0 2 2 2 0 Cache domain DUF842 PF05811.13 CBZ26985.1 - 0.63 9.7 7.1 0.09 12.5 2.8 1.9 2 1 0 2 2 2 0 Eukaryotic protein of unknown function (DUF842) ApoLp-III PF07464.11 CBZ26985.1 - 0.64 10.1 23.9 0.055 13.6 4.5 3.4 2 2 1 3 3 3 0 Apolipophorin-III precursor (apoLp-III) KfrA_N PF11740.8 CBZ26985.1 - 0.82 10.4 12.1 1.1 10.0 8.9 2.5 1 1 1 2 2 2 0 Plasmid replication region DNA-binding N-term ATG_C PF09333.11 CBZ26985.1 - 1.6 9.2 13.8 0.81 10.1 0.9 3.4 2 1 1 3 3 3 0 Autophagy-related protein C terminal domain RRF PF01765.19 CBZ26985.1 - 3.1 7.7 12.6 14 5.6 6.8 3.1 1 1 1 2 2 2 0 Ribosome recycling factor YtxH PF12732.7 CBZ26985.1 - 5.3 7.7 16.4 1.8e+04 -3.8 16.4 3.7 1 1 0 1 1 0 0 YtxH-like protein SCAB_CC PF16712.5 CBZ26985.1 - 6.5 6.6 15.8 1.6 8.6 4.8 3.4 2 1 2 4 4 4 0 Coiled-coil regions of plant-specific actin-binding protein zf-C3HC4 PF00097.25 CBZ26986.1 - 0.001 18.9 12.9 0.001 18.9 12.9 2.8 3 1 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CBZ26986.1 - 0.0027 17.7 9.4 0.0027 17.7 9.4 3.2 2 1 1 3 3 3 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 CBZ26986.1 - 0.0081 16.0 15.7 0.0081 16.0 15.7 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_10 PF16685.5 CBZ26986.1 - 0.02 15.0 16.8 0.035 14.3 12.8 2.6 2 0 0 2 2 2 0 zinc RING finger of MSL2 zf-RING_6 PF14835.6 CBZ26986.1 - 0.37 10.7 13.0 0.84 9.6 13.0 1.5 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-RING_5 PF14634.6 CBZ26986.1 - 1.4 9.0 23.6 0.12 12.3 18.2 2.2 2 0 0 2 2 2 0 zinc-RING finger domain DNA_pol_phi PF04931.13 CBZ26987.1 - 1.7e-06 26.5 16.8 0.00051 18.3 0.7 3.5 2 1 1 3 3 3 2 DNA polymerase phi DUF1736 PF08409.11 CBZ26988.1 - 1.6e-16 60.1 0.3 5.9e-16 58.2 0.3 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1736) TPR_17 PF13431.6 CBZ26988.1 - 0.00083 19.6 0.6 0.12 12.8 0.1 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.6 CBZ26988.1 - 0.14 11.9 0.2 1.4 8.6 0.1 2.4 2 0 0 2 2 2 0 TPR repeat Aa_trans PF01490.18 CBZ26989.1 - 1.3e-59 202.0 32.5 1.5e-59 201.7 32.5 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 CBZ26989.1 - 2.4e-06 26.9 10.0 2.4e-06 26.9 10.0 2.1 2 1 0 2 2 2 1 Tryptophan/tyrosine permease family Y_phosphatase3 PF13350.6 CBZ26991.1 - 4.5e-58 196.9 0.0 5.1e-58 196.8 0.0 1.0 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase2 PF03162.13 CBZ26991.1 - 0.0036 16.9 0.0 0.01 15.5 0.0 1.7 1 1 0 1 1 1 1 Tyrosine phosphatase family PTPlike_phytase PF14566.6 CBZ26991.1 - 0.012 15.8 0.0 0.02 15.0 0.0 1.3 1 0 0 1 1 1 0 Inositol hexakisphosphate Y_phosphatase PF00102.27 CBZ26991.1 - 0.025 14.1 0.0 0.037 13.6 0.0 1.2 1 0 0 1 1 1 0 Protein-tyrosine phosphatase DSPc PF00782.20 CBZ26991.1 - 0.08 12.8 0.0 0.12 12.1 0.0 1.5 1 1 0 1 1 1 0 Dual specificity phosphatase, catalytic domain TRAP_alpha PF03896.16 CBZ26992.1 - 5.6e-14 52.0 0.1 6.4e-14 51.8 0.1 1.2 1 0 0 1 1 1 1 Translocon-associated protein (TRAP), alpha subunit Wzt_C PF14524.6 CBZ26992.1 - 0.063 13.3 0.0 0.1 12.6 0.0 1.3 1 0 0 1 1 1 0 Wzt C-terminal domain zf-Tim10_DDP PF02953.15 CBZ26993.1 - 3.3e-12 45.9 2.4 3.7e-12 45.7 2.4 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger Mito_carr PF00153.27 CBZ26996.1 - 9.9e-09 35.0 0.5 4.9e-07 29.6 0.1 3.1 3 0 0 3 3 3 1 Mitochondrial carrier protein VEK-30 PF12107.8 CBZ26997.1 - 0.2 11.6 3.3 0.74 9.8 3.3 2.0 1 0 0 1 1 1 0 Plasminogen (Pg) ligand in fibrinolytic pathway HEAT_2 PF13646.6 CBZ26997.1 - 2.3 8.7 9.4 0.56 10.6 0.4 3.6 2 2 1 3 3 3 0 HEAT repeats Carn_acyltransf PF00755.20 CBZ26998.1 - 7.4e-87 292.3 0.0 1e-86 291.9 0.0 1.2 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase SEP PF08059.13 CBZ26999.1 - 2.4e-15 56.8 0.0 8.4e-15 55.1 0.0 2.0 1 0 0 1 1 1 1 SEP domain CUE PF02845.16 CBZ26999.1 - 0.00088 18.9 0.0 0.0019 17.9 0.0 1.5 1 0 0 1 1 1 1 CUE domain UBA_4 PF14555.6 CBZ26999.1 - 0.01 15.6 0.1 0.026 14.3 0.1 1.6 1 0 0 1 1 1 0 UBA-like domain THF_DHG_CYH_C PF02882.19 CBZ27001.1 - 1.7e-31 108.7 0.5 1.6e-29 102.3 0.5 2.4 2 0 0 2 2 2 2 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.23 CBZ27001.1 - 6.7e-27 94.1 0.0 1.1e-26 93.4 0.0 1.3 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain DUF463 PF04317.12 CBZ27001.1 - 0.12 11.3 0.0 0.19 10.6 0.0 1.2 1 0 0 1 1 1 0 YcjX-like family, DUF463 MscS_porin PF12795.7 CBZ27002.1 - 0.0057 16.2 12.3 0.0077 15.8 12.3 1.1 1 0 0 1 1 1 1 Mechanosensitive ion channel porin domain Macoilin PF09726.9 CBZ27002.1 - 0.014 14.0 1.6 0.018 13.6 1.6 1.0 1 0 0 1 1 1 0 Macoilin family Spc24 PF08286.11 CBZ27002.1 - 0.12 12.7 1.2 1.2 9.4 0.9 2.2 1 1 0 2 2 2 0 Spc24 subunit of Ndc80 Nup54 PF13874.6 CBZ27002.1 - 0.26 11.4 9.0 1.4 9.0 9.0 1.9 1 1 0 1 1 1 0 Nucleoporin complex subunit 54 OPA3 PF07047.12 CBZ27003.1 - 0.013 15.2 1.5 0.013 15.2 1.5 1.7 2 0 0 2 2 2 0 Optic atrophy 3 protein (OPA3) MutS_III PF05192.18 CBZ27003.1 - 0.043 14.0 0.8 0.047 13.9 0.8 1.2 1 0 0 1 1 1 0 MutS domain III Syntaxin-6_N PF09177.11 CBZ27003.1 - 1.2 9.7 5.4 2.4 8.8 4.3 2.0 2 1 0 2 2 2 0 Syntaxin 6, N-terminal DUF503 PF04456.12 CBZ27005.1 - 0.13 12.2 0.0 0.45 10.4 0.0 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF503) DNA_primase_S PF01896.19 CBZ27006.1 - 9.4e-42 143.0 0.1 1.7e-41 142.2 0.1 1.4 1 1 0 1 1 1 1 DNA primase small subunit cNMP_binding PF00027.29 CBZ27007.1 - 0.00014 21.9 0.1 4.4 7.4 0.0 4.3 4 0 0 4 4 4 2 Cyclic nucleotide-binding domain Ephrin_rec_like PF07699.13 CBZ27008.1 - 0.00014 21.6 70.1 0.00029 20.5 5.9 9.5 6 3 3 9 9 9 5 Putative ephrin-receptor like Serglycin PF04360.12 CBZ27008.1 - 0.2 11.6 5.8 1.4 8.9 6.2 2.1 2 0 0 2 2 2 0 Serglycin Ribosomal_S19 PF00203.21 CBZ27009.1 - 3.5e-29 100.5 0.3 5e-29 100.0 0.3 1.2 1 0 0 1 1 1 1 Ribosomal protein S19 PmbA_TldD PF01523.16 CBZ27009.1 - 0.046 13.6 0.0 0.052 13.4 0.0 1.1 1 0 0 1 1 1 0 Putative modulator of DNA gyrase FlaC_arch PF05377.11 CBZ27010.1 - 0.07 13.5 0.3 1.1 9.7 0.0 2.6 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) Rhabdo_M1 PF03342.13 CBZ27010.1 - 0.1 11.9 1.2 0.23 10.8 1.2 1.6 1 0 0 1 1 1 0 Rhabdovirus M1 matrix protein (M1 polymerase-associated protein) Exonuc_VII_L PF02601.15 CBZ27010.1 - 0.44 10.1 8.7 0.029 14.0 3.0 1.9 2 0 0 2 2 2 0 Exonuclease VII, large subunit FIN1 PF17300.2 CBZ27010.1 - 1.6 8.2 4.8 2.9 7.3 4.8 1.4 1 0 0 1 1 1 0 Filaments in between nuclei protein-1 Acetyltransf_1 PF00583.25 CBZ27011.1 - 1.2e-10 41.7 0.0 1.8e-10 41.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 CBZ27011.1 - 6.2e-07 29.8 0.0 1e-06 29.1 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 CBZ27011.1 - 0.00012 22.0 0.0 0.00021 21.2 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.7 CBZ27011.1 - 0.00029 20.8 0.0 0.00056 19.8 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 CBZ27011.1 - 0.065 12.9 0.0 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Ribosomal_S19 PF00203.21 CBZ27012.1 - 3.5e-29 100.5 0.3 5e-29 100.0 0.3 1.2 1 0 0 1 1 1 1 Ribosomal protein S19 PmbA_TldD PF01523.16 CBZ27012.1 - 0.046 13.6 0.0 0.052 13.4 0.0 1.1 1 0 0 1 1 1 0 Putative modulator of DNA gyrase tRNA_bind PF01588.20 CBZ27013.1 - 9.1e-26 89.8 0.0 2.4e-25 88.5 0.0 1.7 1 0 0 1 1 1 1 Putative tRNA binding domain Dynamin_N PF00350.23 CBZ27014.1 - 5e-13 49.5 0.0 2.6e-12 47.1 0.0 2.1 1 1 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.23 CBZ27014.1 - 2.8e-09 37.1 0.0 1.2e-08 35.0 0.0 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 CBZ27014.1 - 0.00075 19.4 0.6 0.11 12.4 0.5 3.1 2 1 0 2 2 2 1 RsgA GTPase FeoB_N PF02421.18 CBZ27014.1 - 0.0011 18.6 0.1 0.31 10.5 0.0 2.7 3 0 0 3 3 3 2 Ferrous iron transport protein B Roc PF08477.13 CBZ27014.1 - 0.0096 16.1 0.0 1.7 8.9 0.0 2.5 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase GTP_EFTU PF00009.27 CBZ27014.1 - 0.022 14.3 0.1 0.51 9.8 0.0 2.7 3 0 0 3 3 3 0 Elongation factor Tu GTP binding domain DUF5325 PF17259.2 CBZ27014.1 - 0.044 13.7 1.6 0.098 12.5 1.6 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5325) ABC_tran PF00005.27 CBZ27014.1 - 0.075 13.5 0.0 0.13 12.8 0.0 1.5 1 0 0 1 1 1 0 ABC transporter G-alpha PF00503.20 CBZ27014.1 - 0.15 11.2 0.5 10 5.1 0.1 2.3 2 0 0 2 2 2 0 G-protein alpha subunit AAA_18 PF13238.6 CBZ27014.1 - 0.19 12.3 0.0 17 5.9 0.0 2.3 2 0 0 2 2 2 0 AAA domain Pkinase PF00069.25 CBZ27015.1 - 1.2e-43 149.4 0.0 2e-35 122.5 0.0 3.9 3 1 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ27015.1 - 8.5e-18 64.6 0.0 2e-15 56.8 0.0 2.7 2 1 0 2 2 2 2 Protein tyrosine kinase Kdo PF06293.14 CBZ27015.1 - 0.00025 20.5 0.0 0.00045 19.6 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 CBZ27015.1 - 0.0004 20.4 0.2 0.00075 19.5 0.2 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 CBZ27015.1 - 0.11 12.1 0.0 0.18 11.4 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase Haspin_kinase PF12330.8 CBZ27015.1 - 0.12 11.3 0.0 0.18 10.7 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Med26 PF08711.11 CBZ27016.1 - 5.1e-05 23.2 11.0 0.0022 18.0 0.1 3.4 3 0 0 3 3 3 3 TFIIS helical bundle-like domain Peroxidase_ext PF11895.8 CBZ27017.1 - 0.085 12.8 0.1 0.21 11.6 0.1 1.6 1 0 0 1 1 1 0 Fungal peroxidase extension region Paramyxo_C PF01692.18 CBZ27017.1 - 1.8 7.9 3.7 0.91 8.9 0.2 2.1 2 0 0 2 2 2 0 Paramyxovirus non-structural protein C RabGAP-TBC PF00566.18 CBZ27018.1 - 3.6e-33 115.0 0.0 5.4e-33 114.5 0.0 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Hamartin PF04388.12 CBZ27018.1 - 1.3 7.6 2.9 2.3 6.8 2.9 1.3 1 0 0 1 1 1 0 Hamartin protein FHA PF00498.26 CBZ27019.1 - 1.1e-14 54.5 0.0 1.7e-14 53.9 0.0 1.3 1 0 0 1 1 1 1 FHA domain Rotamase PF00639.21 CBZ27019.1 - 5.7e-13 49.6 0.0 6e-12 46.4 0.0 2.5 2 1 0 2 2 2 1 PPIC-type PPIASE domain Rotamase_3 PF13616.6 CBZ27019.1 - 1.2e-08 35.5 0.0 3.3e-08 34.1 0.0 1.7 2 0 0 2 2 2 1 PPIC-type PPIASE domain Yop-YscD_cpl PF16697.5 CBZ27019.1 - 2.8e-08 34.0 0.0 5.8e-08 32.9 0.0 1.4 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain Rotamase_2 PF13145.6 CBZ27019.1 - 0.00044 21.1 2.7 0.0043 17.9 0.0 2.9 3 0 0 3 3 3 1 PPIC-type PPIASE domain DUF5401 PF17380.2 CBZ27019.1 - 7.7 4.4 6.3 11 4.0 6.3 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5401) PPR PF01535.20 CBZ27020.1 - 0.021 15.0 0.0 40 4.8 0.0 4.3 4 0 0 4 4 4 0 PPR repeat ANAPC3 PF12895.7 CBZ27020.1 - 0.16 12.2 0.1 0.59 10.4 0.1 2.0 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_4 PF07721.14 CBZ27020.1 - 0.4 11.4 5.9 0.45 11.3 3.2 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat Kinesin PF00225.23 CBZ27021.1 - 1e-85 287.6 0.1 1.6e-46 158.8 0.0 2.5 2 0 0 2 2 2 2 Kinesin motor domain Microtub_bd PF16796.5 CBZ27021.1 - 1.2e-19 70.7 0.0 3.5e-19 69.2 0.0 1.8 1 0 0 1 1 1 1 Microtubule binding AAA_33 PF13671.6 CBZ27021.1 - 0.023 14.9 0.7 0.14 12.3 0.0 2.6 2 1 0 2 2 2 0 AAA domain KASH_CCD PF14662.6 CBZ27021.1 - 0.16 11.8 36.2 0.2 11.4 15.6 4.2 2 1 1 3 3 3 0 Coiled-coil region of CCDC155 or KASH CCDC144C PF14915.6 CBZ27021.1 - 4.1 6.4 39.3 0.42 9.7 8.0 3.8 3 2 1 4 4 4 0 CCDC144C protein coiled-coil region AAA PF00004.29 CBZ27022.1 - 1.7e-43 148.2 0.1 4e-43 147.0 0.0 1.7 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 CBZ27022.1 - 8.5e-11 41.5 0.0 1.7e-10 40.5 0.0 1.5 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 CBZ27022.1 - 4.3e-06 26.8 0.1 4.3e-05 23.5 0.0 2.4 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 CBZ27022.1 - 1.2e-05 25.6 0.1 0.0054 17.0 0.0 2.5 1 1 1 2 2 2 1 AAA domain AAA_16 PF13191.6 CBZ27022.1 - 1.9e-05 25.1 0.2 0.00082 19.8 0.0 2.2 1 1 0 2 2 2 1 AAA ATPase domain AAA_2 PF07724.14 CBZ27022.1 - 1.9e-05 24.8 0.0 4.6e-05 23.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) DUF815 PF05673.13 CBZ27022.1 - 0.00016 20.9 0.0 0.00031 20.0 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) RuvB_N PF05496.12 CBZ27022.1 - 0.00025 20.8 0.0 0.00066 19.4 0.0 1.7 2 0 0 2 2 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_28 PF13521.6 CBZ27022.1 - 0.0022 18.3 0.0 0.0037 17.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain ATPase_2 PF01637.18 CBZ27022.1 - 0.0052 16.7 0.0 0.35 10.8 0.0 2.4 1 1 1 2 2 2 1 ATPase domain predominantly from Archaea AAA_7 PF12775.7 CBZ27022.1 - 0.0052 16.3 0.0 0.013 15.0 0.0 1.6 1 1 0 1 1 1 1 P-loop containing dynein motor region AAA_33 PF13671.6 CBZ27022.1 - 0.0064 16.7 0.0 0.012 15.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.6 CBZ27022.1 - 0.0081 16.2 0.0 0.02 15.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 CBZ27022.1 - 0.0084 16.5 0.0 0.02 15.3 0.0 1.6 1 0 0 1 1 1 1 RNA helicase Mg_chelatase PF01078.21 CBZ27022.1 - 0.0087 15.5 0.0 0.023 14.1 0.0 1.6 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI TIP49 PF06068.13 CBZ27022.1 - 0.01 15.0 0.0 0.02 14.1 0.0 1.4 1 0 0 1 1 1 0 TIP49 P-loop domain IstB_IS21 PF01695.17 CBZ27022.1 - 0.011 15.5 0.0 0.018 14.8 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_18 PF13238.6 CBZ27022.1 - 0.012 16.1 0.0 0.036 14.6 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_3 PF07726.11 CBZ27022.1 - 0.012 15.4 0.0 0.032 14.1 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.6 CBZ27022.1 - 0.015 15.1 0.2 0.057 13.1 0.1 2.0 3 0 0 3 3 2 0 AAA domain Sigma54_activat PF00158.26 CBZ27022.1 - 0.054 13.2 0.0 0.15 11.8 0.0 1.7 2 0 0 2 2 1 0 Sigma-54 interaction domain NTPase_1 PF03266.15 CBZ27022.1 - 0.055 13.4 0.0 0.12 12.3 0.0 1.6 1 0 0 1 1 1 0 NTPase Parvo_NS1 PF01057.17 CBZ27022.1 - 0.08 12.0 0.0 0.15 11.2 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Zeta_toxin PF06414.12 CBZ27022.1 - 0.11 11.8 0.0 0.25 10.6 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin PhoH PF02562.16 CBZ27022.1 - 0.13 11.7 0.2 0.29 10.6 0.1 1.6 1 1 0 1 1 1 0 PhoH-like protein AAA_19 PF13245.6 CBZ27022.1 - 0.14 12.5 0.1 0.46 10.8 0.1 1.7 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.6 CBZ27022.1 - 0.14 11.7 0.0 0.4 10.2 0.0 1.7 2 0 0 2 2 2 0 AAA domain TsaE PF02367.17 CBZ27022.1 - 0.15 12.1 0.0 0.26 11.3 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_30 PF13604.6 CBZ27022.1 - 0.15 11.8 0.0 0.27 10.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain Rer1 PF03248.13 CBZ27023.1 - 2.4e-53 180.4 4.7 3.1e-53 180.0 4.7 1.0 1 0 0 1 1 1 1 Rer1 family TrmO PF01980.16 CBZ27024.1 - 1.1e-29 103.0 0.0 1.9e-24 86.2 0.0 2.4 2 0 0 2 2 2 2 tRNA-methyltransferase O PWWP PF00855.17 CBZ27024.1 - 3.4e-05 24.2 0.4 0.0002 21.7 0.2 2.4 2 1 0 2 2 2 1 PWWP domain COPR5 PF15340.6 CBZ27024.1 - 0.35 11.5 1.7 0.35 11.5 0.2 1.7 2 0 0 2 2 2 0 Cooperator of PRMT5 family Acetyltransf_3 PF13302.7 CBZ27025.1 - 1.3e-10 42.0 0.1 1.3e-06 29.1 0.0 2.9 2 1 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 CBZ27025.1 - 0.00014 22.1 0.0 0.00026 21.2 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_8 PF13523.6 CBZ27025.1 - 0.0024 17.6 0.8 0.035 13.8 0.1 2.3 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 CBZ27025.1 - 0.026 14.5 0.0 0.049 13.6 0.0 1.3 1 0 0 1 1 1 0 FR47-like protein UQ_con PF00179.26 CBZ27026.1 - 2.3e-42 144.0 0.0 2.9e-42 143.6 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 CBZ27026.1 - 1.2e-05 25.1 0.0 1.6e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 Prokaryotic E2 family B AAA PF00004.29 CBZ27027.1 - 5.4e-38 130.4 0.0 1.7e-37 128.8 0.0 1.9 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 CBZ27027.1 - 3.1e-16 59.1 0.7 8.1e-16 57.7 0.7 1.7 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_lid_3 PF17862.1 CBZ27027.1 - 2.7e-12 46.3 0.2 7e-12 45.0 0.2 1.7 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 CBZ27027.1 - 3.1e-05 24.0 0.1 0.00031 20.8 0.1 2.6 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 CBZ27027.1 - 4.6e-05 23.9 3.7 0.0032 17.9 0.0 3.0 2 2 1 3 3 3 1 AAA ATPase domain AAA_2 PF07724.14 CBZ27027.1 - 0.00042 20.5 0.1 0.004 17.3 0.0 2.4 2 1 0 2 2 2 1 AAA domain (Cdc48 subfamily) RuvB_N PF05496.12 CBZ27027.1 - 0.00044 20.0 0.0 0.00098 18.9 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 CBZ27027.1 - 0.0016 18.7 4.0 0.25 11.6 0.1 3.2 2 1 0 3 3 3 1 AAA domain DUF815 PF05673.13 CBZ27027.1 - 0.0017 17.6 0.2 0.0041 16.3 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_33 PF13671.6 CBZ27027.1 - 0.0071 16.5 1.6 0.036 14.2 0.0 2.6 2 1 0 2 2 2 1 AAA domain Mg_chelatase PF01078.21 CBZ27027.1 - 0.0078 15.6 0.0 0.018 14.4 0.0 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_24 PF13479.6 CBZ27027.1 - 0.023 14.4 0.0 0.065 13.0 0.0 1.9 1 1 0 1 1 1 0 AAA domain ATPase PF06745.13 CBZ27027.1 - 0.054 12.8 0.1 0.14 11.4 0.0 1.7 2 0 0 2 2 2 0 KaiC AAA_25 PF13481.6 CBZ27027.1 - 0.061 12.9 0.5 0.21 11.1 0.0 2.1 3 0 0 3 3 3 0 AAA domain PhoH PF02562.16 CBZ27027.1 - 0.064 12.7 0.1 0.36 10.3 0.0 2.1 2 0 0 2 2 2 0 PhoH-like protein Zeta_toxin PF06414.12 CBZ27027.1 - 0.065 12.5 0.8 0.11 11.7 0.0 1.8 2 0 0 2 2 2 0 Zeta toxin IstB_IS21 PF01695.17 CBZ27027.1 - 0.065 13.0 0.4 0.15 11.7 0.0 1.8 2 0 0 2 2 2 0 IstB-like ATP binding protein Sigma54_activat PF00158.26 CBZ27027.1 - 0.075 12.7 0.0 0.39 10.4 0.0 2.0 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_18 PF13238.6 CBZ27027.1 - 0.094 13.3 0.7 0.33 11.5 0.0 2.3 2 1 1 3 3 3 0 AAA domain TsaE PF02367.17 CBZ27027.1 - 0.14 12.1 0.0 0.29 11.1 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE NACHT PF05729.12 CBZ27027.1 - 0.15 12.0 0.2 0.63 9.9 0.1 2.1 2 0 0 2 2 2 0 NACHT domain Armet PF10208.9 CBZ27030.1 - 0.017 15.1 0.0 3.3 7.6 0.0 2.3 2 0 0 2 2 2 0 Degradation arginine-rich protein for mis-folding Torus PF16131.5 CBZ27031.1 - 0.044 14.5 1.3 0.12 13.1 1.3 1.7 1 0 0 1 1 1 0 Torus domain Prefoldin PF02996.17 CBZ27032.1 - 5e-19 68.4 1.9 6.3e-19 68.1 1.0 1.6 1 1 1 2 2 2 1 Prefoldin subunit LXG PF04740.12 CBZ27032.1 - 0.0018 18.0 1.3 0.0092 15.7 1.0 1.9 2 0 0 2 2 2 1 LXG domain of WXG superfamily Prefoldin_2 PF01920.20 CBZ27032.1 - 0.0022 17.9 1.1 0.024 14.6 0.8 2.1 2 0 0 2 2 2 1 Prefoldin subunit THF_DHG_CYH_C PF02882.19 CBZ27032.1 - 0.051 12.9 0.2 0.11 11.8 0.1 1.5 1 1 1 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain DUF1454 PF07305.12 CBZ27033.1 - 0.0068 15.9 0.0 0.0086 15.5 0.0 1.2 1 1 0 1 1 1 1 Protein of unknown function (DUF1454) Vpu PF00558.19 CBZ27034.1 - 0.23 11.2 0.2 0.56 10.0 0.2 1.5 1 0 0 1 1 1 0 Vpu protein PMG PF05287.12 CBZ27035.1 - 8.8e-32 110.6 93.8 0.00014 21.9 6.3 10.2 1 1 9 10 10 10 10 PMG protein Glyco_hydro_49 PF03718.13 CBZ27035.1 - 3.5e-10 39.9 0.0 1e+02 2.9 0.0 11.7 4 4 6 13 13 13 0 Glycosyl hydrolase family 49 Pentapeptide_2 PF01469.18 CBZ27035.1 - 0.00069 19.4 0.6 21 5.1 0.0 5.0 4 1 0 4 4 4 2 Pentapeptide repeats (8 copies) FAP PF07174.11 CBZ27035.1 - 0.46 9.9 106.5 4.6 6.6 3.6 10.0 1 1 6 8 8 8 0 Fibronectin-attachment protein (FAP) PMG PF05287.12 CBZ27036.1 - 1.5e-51 175.0 132.2 7.3e-06 26.1 4.7 12.6 1 1 11 12 12 12 12 PMG protein Pentapeptide_2 PF01469.18 CBZ27036.1 - 4.6e-09 36.0 0.0 21 5.1 0.0 9.0 8 0 0 8 8 8 2 Pentapeptide repeats (8 copies) YbaB_DNA_bd PF02575.16 CBZ27038.1 - 0.00022 21.4 0.0 0.00041 20.5 0.0 1.4 1 0 0 1 1 1 1 YbaB/EbfC DNA-binding family HIF-1 PF11413.8 CBZ27038.1 - 0.023 14.1 0.0 0.045 13.2 0.0 1.5 1 0 0 1 1 1 0 Hypoxia-inducible factor-1 MMR_HSR1 PF01926.23 CBZ27039.1 - 1.8e-16 60.2 0.0 7e-16 58.3 0.0 2.0 2 0 0 2 2 2 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 CBZ27039.1 - 1.2e-06 28.6 0.0 9.2e-05 22.6 0.0 2.4 1 1 1 2 2 2 1 Dynamin family GTP_EFTU PF00009.27 CBZ27039.1 - 0.00035 20.2 0.0 0.0023 17.5 0.0 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 CBZ27039.1 - 0.0018 18.2 0.0 0.034 14.0 0.0 2.3 2 0 0 2 2 2 1 RsgA GTPase cobW PF02492.19 CBZ27039.1 - 0.02 14.5 0.0 0.14 11.8 0.0 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Septin PF00735.18 CBZ27039.1 - 0.037 13.3 0.0 0.072 12.4 0.0 1.4 2 0 0 2 2 2 0 Septin ABC_tran PF00005.27 CBZ27039.1 - 0.099 13.2 0.0 0.26 11.8 0.0 1.7 1 0 0 1 1 1 0 ABC transporter Sec34 PF04136.15 CBZ27040.1 - 0.03 14.2 10.2 0.27 11.1 2.6 3.1 3 1 0 3 3 3 0 Sec34-like family Rpn9_C PF18261.1 CBZ27040.1 - 0.069 12.8 0.2 0.17 11.5 0.2 1.7 1 0 0 1 1 1 0 Rpn9 C-terminal helix Glu-tRNAGln PF02686.15 CBZ27040.1 - 0.75 10.1 3.5 4.8 7.6 0.1 3.2 3 0 0 3 3 3 0 Glu-tRNAGln amidotransferase C subunit Torus PF16131.5 CBZ27041.1 - 2.8e-05 24.7 0.2 0.27 11.9 0.0 2.4 2 0 0 2 2 2 2 Torus domain zf_CCCH_4 PF18345.1 CBZ27041.1 - 9.4e-05 22.3 12.2 0.00083 19.3 1.8 2.7 2 0 0 2 2 2 2 Zinc finger domain zf-CCCH PF00642.24 CBZ27041.1 - 0.034 14.1 0.6 0.034 14.1 0.6 2.5 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 CBZ27042.1 - 0.00038 20.4 12.6 0.05 13.7 3.9 2.6 2 0 0 2 2 2 2 Zinc finger domain zf-CCCH PF00642.24 CBZ27042.1 - 0.0005 19.9 0.9 0.0005 19.9 0.9 3.5 4 0 0 4 4 4 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 CBZ27042.1 - 0.0066 16.2 9.9 0.076 12.8 2.0 2.6 2 0 0 2 2 2 2 CCCH-type zinc finger zf-CCCH_3 PF15663.5 CBZ27042.1 - 2.5 8.4 5.9 15 5.8 2.0 2.6 2 0 0 2 2 2 0 Zinc-finger containing family NAD_binding_1 PF00175.21 CBZ27044.1 - 1.6e-27 96.3 0.0 2.3e-27 95.8 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 CBZ27044.1 - 8.5e-26 90.2 0.0 1.4e-25 89.5 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.12 CBZ27044.1 - 1.3e-05 25.4 0.1 0.0014 18.8 0.0 2.2 1 1 1 2 2 2 2 Ferric reductase NAD binding domain NAD_binding_1 PF00175.21 CBZ27045.1 - 4.7e-27 94.8 0.0 6.8e-27 94.3 0.0 1.2 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 CBZ27045.1 - 8.8e-21 74.1 0.0 1.7e-20 73.2 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.12 CBZ27045.1 - 4.1e-07 30.2 0.0 2.3e-06 27.8 0.0 1.9 2 0 0 2 2 2 1 Ferric reductase NAD binding domain SUI1 PF01253.22 CBZ27046.1 - 8.1e-12 45.5 0.0 2.2e-11 44.1 0.0 1.8 1 0 0 1 1 1 1 Translation initiation factor SUI1 Pre-PUA PF17832.1 CBZ27046.1 - 0.00011 22.8 0.1 0.00037 21.1 0.1 2.0 1 0 0 1 1 1 1 Pre-PUA-like domain SWIB PF02201.18 CBZ27046.1 - 0.011 15.6 0.1 0.025 14.4 0.1 1.5 1 0 0 1 1 1 0 SWIB/MDM2 domain PUA PF01472.20 CBZ27046.1 - 0.049 13.6 0.0 0.14 12.1 0.0 1.8 1 0 0 1 1 1 0 PUA domain zinc_ribbon_10 PF10058.9 CBZ27047.1 - 5.8e-05 22.7 12.2 0.0056 16.4 0.2 3.3 3 0 0 3 3 3 2 Predicted integral membrane zinc-ribbon metal-binding protein DUF707 PF05212.12 CBZ27047.1 - 0.091 12.0 0.3 0.11 11.8 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF707) zf-Sec23_Sec24 PF04810.15 CBZ27047.1 - 0.13 12.3 11.8 15 5.8 0.1 4.0 3 1 0 3 3 3 0 Sec23/Sec24 zinc finger CCDC50_N PF15295.6 CBZ27047.1 - 0.16 12.1 6.6 1.2 9.4 6.7 2.1 1 1 0 1 1 1 0 Coiled-coil domain-containing protein 50 N-terminus Mu-like_Com PF10122.9 CBZ27047.1 - 0.18 11.2 13.6 0.51 9.8 0.4 4.5 3 1 2 5 5 5 0 Mu-like prophage protein Com OrfB_Zn_ribbon PF07282.11 CBZ27047.1 - 0.7 9.9 11.3 0.14 12.1 0.6 3.5 4 0 0 4 4 4 0 Putative transposase DNA-binding domain zinc_ribbon_12 PF11331.8 CBZ27047.1 - 3.3 7.6 25.0 0.072 12.9 3.9 4.8 2 2 3 5 5 5 0 Probable zinc-ribbon domain Cytochrom_c3_2 PF14537.6 CBZ27047.1 - 3.8 8.0 16.2 0.24 11.9 4.2 2.7 2 1 1 3 3 3 0 Cytochrome c3 Pkinase PF00069.25 CBZ27048.1 - 9.5e-64 215.3 0.0 1.1e-63 215.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ27048.1 - 7.3e-33 113.9 0.0 9.6e-33 113.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CBZ27048.1 - 8.8e-05 22.0 0.0 0.00011 21.6 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 CBZ27048.1 - 0.029 13.2 0.2 0.082 11.7 0.0 1.7 2 0 0 2 2 2 0 Fungal protein kinase Kdo PF06293.14 CBZ27048.1 - 0.032 13.6 0.0 0.052 12.9 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 CBZ27048.1 - 0.12 12.3 0.0 0.31 10.9 0.0 1.7 1 1 1 2 2 2 0 Phosphotransferase enzyme family MMR_HSR1 PF01926.23 CBZ27049.1 - 1.4e-16 60.6 0.0 5.3e-16 58.7 0.0 2.0 2 0 0 2 2 2 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 CBZ27049.1 - 7.8e-07 29.3 0.0 7.4e-05 22.9 0.0 2.4 1 1 0 2 2 2 1 Dynamin family GTP_EFTU PF00009.27 CBZ27049.1 - 0.00022 20.8 0.0 0.0017 17.9 0.0 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 CBZ27049.1 - 0.0012 18.8 0.0 0.027 14.4 0.0 2.3 2 0 0 2 2 2 1 RsgA GTPase cobW PF02492.19 CBZ27049.1 - 0.014 15.0 0.0 0.11 12.1 0.0 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Septin PF00735.18 CBZ27049.1 - 0.027 13.8 0.0 0.056 12.7 0.0 1.5 2 0 0 2 2 2 0 Septin ABC_tran PF00005.27 CBZ27049.1 - 0.08 13.5 0.0 0.21 12.1 0.0 1.7 1 0 0 1 1 1 0 ABC transporter FeoB_N PF02421.18 CBZ27049.1 - 0.25 10.9 0.0 0.67 9.5 0.0 1.8 1 1 0 1 1 1 0 Ferrous iron transport protein B Vpu PF00558.19 CBZ27050.1 - 0.23 11.2 0.2 0.56 10.0 0.2 1.5 1 0 0 1 1 1 0 Vpu protein Stealth_CR2 PF11380.8 CBZ27051.1 - 1.2e-11 44.7 0.0 6.4e-09 36.0 0.0 2.4 2 0 0 2 2 2 2 Stealth protein CR2, conserved region 2 Stealth_CR3 PF17102.5 CBZ27051.1 - 0.031 14.2 0.8 0.1 12.5 0.8 2.0 1 0 0 1 1 1 0 Stealth protein CR3, conserved region 3 Ribosomal_L22 PF00237.19 CBZ27052.1 - 8.9e-13 48.4 0.0 1.3e-12 47.8 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e IQ PF00612.27 CBZ27055.1 - 0.73 9.8 4.8 2 8.4 4.8 1.8 1 0 0 1 1 1 0 IQ calmodulin-binding motif Prp18 PF02840.15 CBZ27056.1 - 7e-11 42.4 0.1 7e-11 42.4 0.1 2.0 2 0 0 2 2 2 1 Prp18 domain DUF5620 PF18522.1 CBZ27056.1 - 0.026 14.9 0.0 0.093 13.1 0.0 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF5620) MSP1_C PF07462.11 CBZ27056.1 - 6.8 5.3 5.0 11 4.6 5.0 1.3 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus EF-hand_6 PF13405.6 CBZ27057.1 - 1.6e-09 36.9 0.1 0.4 10.7 0.0 4.5 4 0 0 4 4 4 4 EF-hand domain EF-hand_7 PF13499.6 CBZ27057.1 - 4.1e-07 30.4 0.9 0.024 15.1 0.0 3.5 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_1 PF00036.32 CBZ27057.1 - 1.6e-05 24.1 0.0 1.1 8.9 0.0 3.9 4 0 0 4 4 4 3 EF hand EF-hand_8 PF13833.6 CBZ27057.1 - 0.012 15.4 0.0 2.8 7.9 0.0 3.1 3 0 0 3 3 3 0 EF-hand domain pair AAA PF00004.29 CBZ27058.1 - 1.4e-13 51.4 0.0 1.7e-07 31.8 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 CBZ27058.1 - 2e-05 24.6 0.0 3.9e-05 23.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 CBZ27058.1 - 0.33 11.3 1.6 0.69 10.3 0.4 2.2 2 1 0 2 2 2 0 AAA ATPase domain AAA PF00004.29 CBZ27059.1 - 1.4e-13 51.5 0.0 1.7e-07 31.7 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 CBZ27059.1 - 1.4e-05 25.1 0.0 4e-05 23.6 0.0 1.9 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 CBZ27059.1 - 0.41 11.0 1.9 0.7 10.3 0.5 2.2 2 1 0 2 2 2 0 AAA ATPase domain Pkinase PF00069.25 CBZ27060.1 - 2.8e-62 210.5 0.0 3.4e-62 210.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ27060.1 - 1.7e-42 145.5 0.0 2.1e-42 145.2 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CBZ27060.1 - 6.8e-09 35.4 0.0 9.2e-09 35.0 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 CBZ27060.1 - 0.00064 18.6 0.0 0.00096 18.0 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 CBZ27060.1 - 0.003 17.0 0.0 0.013 14.9 0.0 1.9 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 CBZ27060.1 - 0.029 14.3 0.0 0.052 13.5 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kinesin PF00225.23 CBZ27061.1 - 1.1e-87 294.1 0.2 4.7e-87 292.0 0.2 2.2 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 CBZ27061.1 - 1.6e-09 37.9 9.1 1.5e-06 28.2 0.3 3.9 4 0 0 4 4 4 2 Microtubule binding KELK PF15796.5 CBZ27061.1 - 0.0017 18.8 3.0 0.0017 18.8 3.0 9.5 9 2 0 10 10 10 1 KELK-motif containing domain of MRCK Ser/Thr protein kinase NPR2 PF06218.11 CBZ27062.1 - 0.00096 18.0 0.0 0.013 14.3 0.0 2.1 2 0 0 2 2 2 2 Nitrogen permease regulator 2 WD40 PF00400.32 CBZ27063.1 - 0.00041 21.1 0.0 0.14 13.0 0.0 2.9 2 0 0 2 2 2 2 WD domain, G-beta repeat UAA PF08449.11 CBZ27066.1 - 1e-30 107.0 10.3 3.7e-30 105.2 10.3 1.8 1 1 0 1 1 1 1 UAA transporter family LigA PF07746.11 CBZ27066.1 - 0.078 13.1 0.1 0.32 11.2 0.1 2.0 2 0 0 2 2 2 0 Aromatic-ring-opening dioxygenase LigAB, LigA subunit Kelch_5 PF13854.6 CBZ27068.1 - 1e-23 82.8 7.2 1.4e-06 28.1 0.1 7.2 6 1 0 6 6 6 5 Kelch motif Kelch_4 PF13418.6 CBZ27068.1 - 2.9e-19 68.8 12.1 0.00076 19.4 0.0 7.1 5 2 1 6 6 6 4 Galactose oxidase, central domain Kelch_6 PF13964.6 CBZ27068.1 - 1.3e-17 63.4 6.9 0.0053 17.0 0.1 6.2 7 0 0 7 7 7 4 Kelch motif Kelch_3 PF13415.6 CBZ27068.1 - 4.6e-16 58.7 29.4 0.00025 21.3 0.2 8.4 8 1 0 8 8 8 4 Galactose oxidase, central domain Kelch_1 PF01344.25 CBZ27068.1 - 6.1e-11 41.7 14.4 0.00044 19.8 0.3 7.1 7 0 0 7 7 7 4 Kelch motif Kelch_2 PF07646.15 CBZ27068.1 - 9.5e-09 34.9 13.0 0.00017 21.4 0.3 6.0 6 1 0 6 6 6 2 Kelch motif BTB PF00651.31 CBZ27068.1 - 0.0004 20.6 0.6 0.003 17.8 0.0 2.7 3 0 0 3 3 3 1 BTB/POZ domain CheY-binding PF09078.11 CBZ27068.1 - 0.004 17.3 0.1 0.38 10.9 0.0 2.6 2 0 0 2 2 2 1 CheY binding TSP9 PF11493.8 CBZ27068.1 - 0.18 12.5 0.6 2.7 8.7 0.3 3.2 2 0 0 2 2 2 0 Thylakoid soluble phosphoprotein TSP9 MFS_1 PF07690.16 CBZ27070.1 - 2.1e-24 86.2 21.5 2.1e-24 86.2 21.5 2.2 1 1 1 2 2 2 1 Major Facilitator Superfamily OATP PF03137.20 CBZ27070.1 - 5.3e-17 61.3 14.0 4.2e-11 41.9 1.6 3.7 2 2 2 4 4 4 3 Organic Anion Transporter Polypeptide (OATP) family Sugar_tr PF00083.24 CBZ27070.1 - 4.4e-16 58.8 1.6 4.4e-16 58.8 1.6 2.1 2 0 0 2 2 2 1 Sugar (and other) transporter MFS_4 PF06779.14 CBZ27070.1 - 6.7e-08 32.2 4.0 6.7e-08 32.2 4.0 2.4 2 0 0 2 2 2 2 Uncharacterised MFS-type transporter YbfB MFS_1_like PF12832.7 CBZ27070.1 - 2.7 6.8 21.6 0.15 10.9 3.3 2.8 2 1 1 3 3 3 0 MFS_1 like family LSM PF01423.22 CBZ27071.1 - 5.8e-13 48.3 0.1 7.4e-13 48.0 0.1 1.1 1 0 0 1 1 1 1 LSM domain SP2 PF03014.14 CBZ27071.1 - 0.0061 15.0 0.1 0.0066 14.9 0.1 1.0 1 0 0 1 1 1 1 Structural protein 2 SM-ATX PF14438.6 CBZ27071.1 - 0.017 15.3 0.0 0.025 14.7 0.0 1.4 1 0 0 1 1 1 0 Ataxin 2 SM domain Med20 PF08612.11 CBZ27071.1 - 0.079 12.3 0.0 0.083 12.2 0.0 1.2 1 0 0 1 1 1 0 TATA-binding related factor (TRF) of subunit 20 of Mediator complex CCDC106 PF15794.5 CBZ27073.1 - 0.022 14.5 0.5 0.04 13.6 0.5 1.3 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 DUF2561 PF10812.8 CBZ27073.1 - 0.58 10.2 3.7 0.19 11.7 0.3 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2561) CRAL_TRIO PF00650.20 CBZ27074.1 - 7e-13 48.6 0.0 2.1e-12 47.0 0.0 1.7 1 1 0 1 1 1 1 CRAL/TRIO domain zf-C3HC4_3 PF13920.6 CBZ27075.1 - 7.5e-09 35.3 10.6 7.5e-09 35.3 10.6 1.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) DUF5519 PF17648.1 CBZ27075.1 - 0.036 13.9 0.1 0.099 12.5 0.1 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5519) Prok-RING_4 PF14447.6 CBZ27075.1 - 0.081 12.8 9.8 0.18 11.7 9.8 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 CBZ27075.1 - 7.2 6.7 16.7 0.22 11.5 10.0 1.9 2 0 0 2 2 2 0 zinc-RING finger domain AAA_6 PF12774.7 CBZ27076.1 - 5.7e-130 433.1 0.0 1.4e-126 422.0 0.0 4.0 3 1 0 3 3 3 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 CBZ27076.1 - 7.1e-86 288.8 0.9 4e-85 286.3 0.0 2.5 2 0 0 2 2 2 1 Dynein heavy chain, N-terminal region 2 AAA_9 PF12781.7 CBZ27076.1 - 1.2e-62 210.9 0.0 3.8e-60 202.8 0.0 2.6 2 0 0 2 2 2 1 ATP-binding dynein motor region AAA_8 PF12780.7 CBZ27076.1 - 1.9e-59 201.1 0.0 7.5e-37 127.0 0.0 2.8 2 0 0 2 2 2 2 P-loop containing dynein motor region D4 AAA_7 PF12775.7 CBZ27076.1 - 3.7e-44 150.4 0.0 2.4e-37 128.2 0.0 4.7 4 0 0 4 4 4 2 P-loop containing dynein motor region MT PF12777.7 CBZ27076.1 - 1.1e-35 123.3 2.0 1.7e-35 122.7 2.0 1.3 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_5 PF07728.14 CBZ27076.1 - 7.4e-28 97.3 0.0 3.1e-10 40.2 0.0 6.3 4 2 0 4 4 4 4 AAA domain (dynein-related subfamily) Dynein_heavy PF03028.15 CBZ27076.1 - 1.1e-22 80.4 0.0 6.8e-22 77.8 0.0 2.6 2 0 0 2 2 1 1 Dynein heavy chain region D6 P-loop domain AAA_lid_11 PF18198.1 CBZ27076.1 - 9.6e-21 74.3 0.0 2.1e-20 73.2 0.0 1.6 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain Dynein_C PF18199.1 CBZ27076.1 - 1.9e-20 73.3 0.0 4.8e-20 72.0 0.0 1.7 1 0 0 1 1 1 1 Dynein heavy chain C-terminal domain AAA PF00004.29 CBZ27076.1 - 3.1e-20 73.0 0.1 8.2e-06 26.3 0.0 5.2 5 0 0 5 5 4 4 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 CBZ27076.1 - 6.1e-15 55.7 5.3 1e-05 25.8 0.0 7.2 6 1 0 6 6 5 2 AAA domain AAA_16 PF13191.6 CBZ27076.1 - 3.4e-12 47.1 8.0 0.087 13.2 0.0 7.8 6 0 0 6 6 4 4 AAA ATPase domain AAA_18 PF13238.6 CBZ27076.1 - 1e-07 32.6 0.0 2.6 8.6 0.0 5.4 4 0 0 4 4 4 2 AAA domain AAA_33 PF13671.6 CBZ27076.1 - 4.8e-07 30.0 0.9 0.46 10.7 0.0 5.1 4 0 0 4 4 4 2 AAA domain FtsK_SpoIIIE PF01580.18 CBZ27076.1 - 1.1e-06 28.2 0.1 0.015 14.6 0.0 3.8 3 0 0 3 3 3 2 FtsK/SpoIIIE family AAA_24 PF13479.6 CBZ27076.1 - 1.2e-06 28.4 0.4 2.4 7.9 0.0 4.4 4 0 0 4 4 4 2 AAA domain IstB_IS21 PF01695.17 CBZ27076.1 - 7e-06 25.9 2.0 0.026 14.3 0.0 4.6 5 0 0 5 5 4 1 IstB-like ATP binding protein T2SSE PF00437.20 CBZ27076.1 - 1.1e-05 24.7 0.0 0.54 9.3 0.0 4.2 4 0 0 4 4 4 1 Type II/IV secretion system protein AAA_25 PF13481.6 CBZ27076.1 - 2e-05 24.2 1.0 0.088 12.4 0.0 4.1 3 0 0 3 3 3 1 AAA domain AAA_30 PF13604.6 CBZ27076.1 - 4.1e-05 23.4 5.0 0.75 9.5 0.1 4.4 4 0 0 4 4 4 2 AAA domain AAA_lid_1 PF17857.1 CBZ27076.1 - 0.00031 20.9 0.0 0.0011 19.2 0.0 2.0 1 0 0 1 1 1 1 AAA+ lid domain RNA_helicase PF00910.22 CBZ27076.1 - 0.00031 21.1 0.3 4.6 7.7 0.0 4.5 4 0 0 4 4 4 0 RNA helicase AAA_19 PF13245.6 CBZ27076.1 - 0.00045 20.6 6.2 1.3 9.3 0.0 4.9 5 0 0 5 5 4 1 AAA domain Sigma54_activat PF00158.26 CBZ27076.1 - 0.00052 19.7 0.0 0.51 10.0 0.0 3.4 3 0 0 3 3 3 1 Sigma-54 interaction domain Mg_chelatase PF01078.21 CBZ27076.1 - 0.00068 19.1 5.3 0.23 10.8 0.0 3.8 4 0 0 4 4 3 2 Magnesium chelatase, subunit ChlI AAA_29 PF13555.6 CBZ27076.1 - 0.0011 18.7 0.4 2.1 8.2 0.0 3.9 3 0 0 3 3 3 1 P-loop containing region of AAA domain MAD PF05557.13 CBZ27076.1 - 0.0015 17.0 1.2 0.0015 17.0 1.2 2.7 3 0 0 3 3 3 1 Mitotic checkpoint protein RsgA_GTPase PF03193.16 CBZ27076.1 - 0.0016 18.4 0.0 16 5.4 0.0 3.8 3 0 0 3 3 3 0 RsgA GTPase RuvB_N PF05496.12 CBZ27076.1 - 0.0028 17.4 0.2 1.2 8.9 0.0 3.6 3 0 0 3 3 3 1 Holliday junction DNA helicase RuvB P-loop domain Rad17 PF03215.15 CBZ27076.1 - 0.0037 17.2 0.0 5.5 6.9 0.0 4.1 4 0 0 4 4 4 0 Rad17 P-loop domain ABC_tran PF00005.27 CBZ27076.1 - 0.0042 17.6 3.2 2.4 8.7 0.0 4.4 4 0 0 4 4 3 1 ABC transporter AAA_28 PF13521.6 CBZ27076.1 - 0.005 17.1 0.5 30 4.8 0.0 5.1 4 0 0 4 4 4 0 AAA domain Dynein_AAA_lid PF17852.1 CBZ27076.1 - 0.044 13.9 0.1 0.2 11.7 0.1 2.2 1 0 0 1 1 1 0 Dynein heavy chain AAA lid domain TrwB_AAD_bind PF10412.9 CBZ27076.1 - 0.084 11.8 1.4 3.8 6.3 0.2 3.1 3 0 0 3 3 3 0 Type IV secretion-system coupling protein DNA-binding domain NB-ARC PF00931.22 CBZ27076.1 - 0.16 11.1 0.3 3.1 6.9 0.0 3.0 3 0 0 3 3 3 0 NB-ARC domain SRP54 PF00448.22 CBZ27076.1 - 0.16 11.6 2.1 10 5.7 0.1 3.8 4 0 0 4 4 4 0 SRP54-type protein, GTPase domain TIP49 PF06068.13 CBZ27076.1 - 0.18 11.0 0.3 38 3.3 0.0 3.0 3 0 0 3 3 3 0 TIP49 P-loop domain DUF87 PF01935.17 CBZ27076.1 - 0.23 11.5 2.1 25 4.8 0.1 4.0 4 0 0 4 4 4 0 Helicase HerA, central domain AAA_11 PF13086.6 CBZ27076.1 - 0.44 10.3 13.5 1.6 8.5 0.0 5.0 5 0 0 5 5 5 0 AAA domain Noelin-1 PF12308.8 CBZ27076.1 - 4.8 7.2 6.0 54 3.9 0.7 4.1 3 0 0 3 3 3 0 Neurogenesis glycoprotein HrpB7 PF09486.10 CBZ27076.1 - 7.4 6.9 30.9 0.053 13.9 5.8 4.8 2 1 0 2 2 2 0 Bacterial type III secretion protein (HrpB7) Lactamase_B_2 PF12706.7 CBZ27077.1 - 4.3e-13 49.2 0.0 1e-08 34.9 0.1 2.4 1 1 0 2 2 2 2 Beta-lactamase superfamily domain Lactamase_B PF00753.27 CBZ27077.1 - 6.2e-05 23.1 0.6 0.00013 22.0 0.6 1.5 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_3 PF13483.6 CBZ27077.1 - 0.0055 16.6 0.0 3.8 7.4 0.0 2.4 2 1 0 2 2 2 2 Beta-lactamase superfamily domain Lactamase_B_2 PF12706.7 CBZ27078.1 - 9.7e-12 44.8 0.3 2.5e-06 27.2 0.2 2.7 1 1 0 2 2 2 2 Beta-lactamase superfamily domain DUF3330 PF11809.8 CBZ27078.1 - 0.021 14.9 0.9 0.12 12.5 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3330) Adap_comp_sub PF00928.21 CBZ27079.1 - 6.4e-84 281.4 0.3 9.4e-84 280.9 0.3 1.3 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 CBZ27079.1 - 0.00099 19.1 0.5 0.0018 18.2 0.5 1.4 1 0 0 1 1 1 1 Clathrin adaptor complex small chain PhetRS_B1 PF18262.1 CBZ27079.1 - 0.073 13.3 0.0 0.16 12.2 0.0 1.6 1 0 0 1 1 1 0 Phe-tRNA synthetase beta subunit B1 domain Pkinase PF00069.25 CBZ27080.1 - 8.8e-13 48.2 0.0 1.6e-05 24.4 0.0 2.4 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ27080.1 - 0.0042 16.4 0.0 0.14 11.4 0.0 2.3 2 0 0 2 2 2 1 Protein tyrosine kinase Kdo PF06293.14 CBZ27080.1 - 0.084 12.2 0.1 0.16 11.3 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.25 CBZ27082.1 - 1.2e-23 83.8 0.0 2.8e-19 69.5 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ27082.1 - 2.4e-08 33.6 0.0 4.1e-08 32.8 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CBZ27082.1 - 0.027 13.8 0.0 0.047 13.0 0.0 1.4 1 0 0 1 1 1 0 Kinase-like zf-MYND PF01753.18 CBZ27083.1 - 1.2 9.3 7.3 2.3 8.4 7.3 1.5 1 0 0 1 1 1 0 MYND finger ChaC PF04752.12 CBZ27084.1 - 6.7e-47 159.8 0.0 8.1e-47 159.6 0.0 1.0 1 0 0 1 1 1 1 ChaC-like protein ChaC PF04752.12 CBZ27085.1 - 8.8e-44 149.7 0.1 9e-43 146.4 0.1 2.0 1 1 0 1 1 1 1 ChaC-like protein WD40 PF00400.32 CBZ27086.1 - 7.8e-09 36.0 0.5 0.00026 21.7 0.0 4.0 3 0 0 3 3 3 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBZ27086.1 - 0.056 13.8 0.0 7.3 7.0 0.0 2.8 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain SHS2_Rpb7-N PF03876.17 CBZ27088.1 - 0.0007 19.9 0.0 0.022 15.2 0.0 2.5 2 0 0 2 2 2 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 PSRP-3_Ycf65 PF04839.13 CBZ27088.1 - 0.59 10.4 1.4 5.8 7.2 0.0 2.8 3 0 0 3 3 3 0 Plastid and cyanobacterial ribosomal protein (PSRP-3 / Ycf65) GTP_EFTU PF00009.27 CBZ27089.1 - 1.3e-32 112.9 3.7 7.9e-31 107.1 3.7 2.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 CBZ27089.1 - 9e-10 38.6 0.2 1.7e-09 37.7 0.2 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 CBZ27089.1 - 2.9e-05 23.6 0.1 5.3e-05 22.8 0.1 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B SRPRB PF09439.10 CBZ27089.1 - 0.00032 20.2 0.0 0.00063 19.2 0.0 1.4 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit IF-2 PF11987.8 CBZ27089.1 - 0.00046 20.3 0.0 0.002 18.2 0.0 2.1 2 0 0 2 2 2 1 Translation-initiation factor 2 PduV-EutP PF10662.9 CBZ27089.1 - 0.0011 18.8 0.1 0.0036 17.1 0.1 1.9 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation Roc PF08477.13 CBZ27089.1 - 0.016 15.4 0.0 0.031 14.5 0.0 1.4 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase Dynamin_N PF00350.23 CBZ27089.1 - 0.04 14.0 2.2 1.5 8.9 0.1 2.8 2 1 1 3 3 3 0 Dynamin family WD40 PF00400.32 CBZ27090.1 - 3.5e-12 46.6 17.4 0.0012 19.6 0.4 7.0 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBZ27090.1 - 0.013 15.8 0.0 11 6.4 0.0 2.9 2 1 1 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain Nucleoporin_N PF08801.11 CBZ27090.1 - 0.11 11.2 0.0 9.1 4.9 0.0 2.3 2 0 0 2 2 2 0 Nup133 N terminal like MORN PF02493.20 CBZ27092.1 - 9.2e-06 25.3 12.2 0.19 11.7 0.1 3.7 3 0 0 3 3 3 3 MORN repeat Ribonuc_red_sm PF00268.21 CBZ27094.1 - 2.4e-111 371.7 0.1 3e-111 371.4 0.1 1.0 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain Atg8 PF02991.16 CBZ27095.1 - 2.1e-12 47.1 0.0 2.5e-11 43.7 0.0 2.0 2 0 0 2 2 2 1 Autophagy protein Atg8 ubiquitin like APG12 PF04110.13 CBZ27095.1 - 0.00052 20.4 0.0 0.00095 19.5 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 ATP-grasp_5 PF13549.6 CBZ27096.1 - 0.11 11.9 0.1 0.23 10.9 0.1 1.4 1 0 0 1 1 1 0 ATP-grasp domain PKcGMP_CC PF16808.5 CBZ27097.1 - 3.1e-59 196.5 625.9 0.11 12.3 2.0 74.7 21 5 55 76 76 76 53 Coiled-coil N-terminus of cGMP-dependent protein kinase DUF641 PF04859.12 CBZ27097.1 - 1.1e-42 145.4 466.5 0.03 14.6 10.2 42.9 8 5 48 56 56 56 43 Plant protein of unknown function (DUF641) Fez1 PF06818.15 CBZ27097.1 - 6.4e-13 49.6 561.8 0.23 11.9 17.2 27.6 7 3 21 28 28 28 12 Fez1 Lebercilin PF15619.6 CBZ27097.1 - 2.9e-05 23.8 610.1 0.02 14.6 17.0 40.1 12 3 29 44 44 44 23 Ciliary protein causing Leber congenital amaurosis disease Myosin_tail_1 PF01576.19 CBZ27097.1 - 0.00059 17.8 105.4 0.00059 17.8 105.4 15.1 6 2 7 14 14 14 9 Myosin tail MTH865 PF07747.11 CBZ27097.1 - 0.0062 16.3 0.2 80 3.1 0.0 5.0 3 0 0 3 3 3 0 MTH865-like family BST2 PF16716.5 CBZ27097.1 - 0.27 11.8 432.6 0.11 13.1 9.0 31.3 13 4 27 43 43 43 0 Bone marrow stromal antigen 2 COMP PF11598.8 CBZ27098.1 - 3.1e-119 389.3 345.0 0.62 10.6 0.2 66.5 66 0 0 66 66 66 65 Cartilage oligomeric matrix protein TMF_DNA_bd PF12329.8 CBZ27098.1 - 1.7e-35 120.8 339.9 0.29 11.1 1.9 64.4 50 14 17 67 67 67 37 TATA element modulatory factor 1 DNA binding DUF641 PF04859.12 CBZ27098.1 - 2.9e-23 82.6 428.6 0.028 14.8 3.1 67.1 10 7 55 68 68 68 36 Plant protein of unknown function (DUF641) Fez1 PF06818.15 CBZ27098.1 - 4.8e-18 66.3 378.6 0.19 12.2 8.2 26.5 3 2 36 39 39 39 29 Fez1 ATG16 PF08614.11 CBZ27098.1 - 2.7e-06 27.8 560.7 0.3 11.3 15.7 29.7 5 2 29 35 35 35 15 Autophagy protein 16 (ATG16) DUF4201 PF13870.6 CBZ27098.1 - 0.0022 17.8 1.0 0.0022 17.8 1.0 33.1 17 11 24 45 45 45 3 Domain of unknown function (DUF4201) 3-PAP PF12578.8 CBZ27098.1 - 0.022 14.5 2.2 70 3.2 0.1 7.9 2 0 0 2 2 2 0 Myotubularin-associated protein Methyltransf_28 PF02636.17 CBZ27099.1 - 8.7e-37 127.2 0.0 1.2e-36 126.7 0.0 1.1 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase RrnaAD PF00398.20 CBZ27099.1 - 0.0024 17.0 0.0 0.0041 16.2 0.0 1.3 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_12 PF08242.12 CBZ27099.1 - 0.0031 18.2 0.0 0.0063 17.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CBZ27099.1 - 0.0037 17.9 0.0 0.011 16.4 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CBZ27099.1 - 0.018 14.8 0.0 0.031 14.1 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain DHHC PF01529.20 CBZ27100.1 - 1.2e-31 109.6 7.6 1.2e-31 109.6 7.6 1.8 2 0 0 2 2 2 1 DHHC palmitoyltransferase polyprenyl_synt PF00348.17 CBZ27101.1 - 9.3e-74 247.7 0.5 1.2e-73 247.4 0.5 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase Spc7 PF08317.11 CBZ27102.1 - 0.64 8.8 60.5 1.2 7.9 19.5 3.3 1 1 1 3 3 3 0 Spc7 kinetochore protein Ribosomal_L28e PF01778.17 CBZ27103.1 - 1.6e-28 99.8 0.0 3.6e-28 98.6 0.0 1.5 1 0 0 1 1 1 1 Ribosomal L28e protein family Mak16 PF04874.14 CBZ27103.1 - 3.9e-15 56.3 23.6 1.2e-14 54.7 23.1 2.1 1 1 1 2 2 2 1 Mak16 protein C-terminal region Gag_p24 PF00607.20 CBZ27103.1 - 0.03 14.2 0.1 0.079 12.8 0.1 1.7 1 1 1 2 2 2 0 gag gene protein p24 (core nucleocapsid protein) YqfQ PF14181.6 CBZ27103.1 - 0.6 10.3 9.1 0.12 12.5 4.9 1.8 2 0 0 2 2 2 0 YqfQ-like protein BNIP2 PF12496.8 CBZ27103.1 - 0.61 10.5 5.6 1.5 9.2 5.6 1.7 1 1 0 1 1 1 0 Bcl2-/adenovirus E1B nineteen kDa-interacting protein 2 CDC45 PF02724.14 CBZ27103.1 - 1 7.5 16.5 0.58 8.4 14.9 1.3 1 1 0 1 1 1 0 CDC45-like protein MORN PF02493.20 CBZ27105.1 - 4.8e-48 158.3 79.4 2.5e-05 23.9 0.3 12.9 13 0 0 13 13 13 12 MORN repeat EF-hand_1 PF00036.32 CBZ27106.1 - 4.3e-27 91.6 8.2 2.8e-08 32.7 0.4 4.5 4 1 1 5 5 5 4 EF hand EF-hand_7 PF13499.6 CBZ27106.1 - 4.4e-25 87.9 1.3 2e-11 44.2 0.1 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 CBZ27106.1 - 1.7e-20 71.2 4.6 6e-07 28.9 0.1 4.7 3 1 2 5 5 5 3 EF-hand domain EF-hand_8 PF13833.6 CBZ27106.1 - 8e-19 67.2 7.5 6.7e-10 38.7 0.3 3.9 1 1 3 4 4 4 4 EF-hand domain pair EF-hand_5 PF13202.6 CBZ27106.1 - 6e-17 60.3 9.9 1.7e-05 24.1 0.1 3.9 4 0 0 4 4 4 3 EF hand EF-hand_9 PF14658.6 CBZ27106.1 - 1.4e-07 31.8 0.1 1.6e-06 28.3 0.0 2.1 2 1 0 2 2 2 1 EF-hand domain EF-hand_4 PF12763.7 CBZ27106.1 - 4.3e-07 29.8 2.8 0.048 13.6 0.8 3.3 1 1 1 3 3 3 2 Cytoskeletal-regulatory complex EF hand Ribosomal_L11 PF00298.19 CBZ27106.1 - 0.024 15.1 0.0 3.2 8.3 0.0 2.3 1 1 1 2 2 2 0 Ribosomal protein L11, RNA binding domain EFhand_Ca_insen PF08726.10 CBZ27106.1 - 0.043 13.9 0.2 9.6 6.4 0.0 2.7 2 1 0 2 2 2 0 Ca2+ insensitive EF hand SPARC_Ca_bdg PF10591.9 CBZ27106.1 - 0.066 13.5 0.1 0.2 12.0 0.0 1.8 1 1 1 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region DUF3911 PF13050.6 CBZ27106.1 - 0.081 13.0 0.1 0.19 11.9 0.1 1.8 2 1 0 2 2 2 0 Protein of unknown function (DUF3911) MIP PF00230.20 CBZ27107.1 - 5.1e-24 85.2 13.5 4.4e-23 82.2 13.4 2.0 1 1 0 1 1 1 1 Major intrinsic protein FKBP_C PF00254.28 CBZ27108.1 - 9.5e-30 102.8 0.0 1.1e-29 102.6 0.0 1.1 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase zf-RanBP PF00641.18 CBZ27109.1 - 0.16 11.3 0.5 0.33 10.3 0.5 1.4 1 0 0 1 1 1 0 Zn-finger in Ran binding protein and others Pro_isomerase PF00160.21 CBZ27110.1 - 1.2e-35 123.1 0.0 1.6e-35 122.7 0.0 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD EF-hand_8 PF13833.6 CBZ27111.1 - 6.3e-07 29.2 0.2 6.3e-07 29.2 0.2 2.0 2 0 0 2 2 2 1 EF-hand domain pair EFhand_Ca_insen PF08726.10 CBZ27111.1 - 0.00072 19.6 0.2 0.0036 17.4 0.0 2.1 2 0 0 2 2 2 1 Ca2+ insensitive EF hand EF-hand_1 PF00036.32 CBZ27111.1 - 0.023 14.2 0.6 0.085 12.4 0.1 2.1 2 0 0 2 2 2 0 EF hand EF-hand_6 PF13405.6 CBZ27111.1 - 0.058 13.3 0.1 0.36 10.9 0.1 2.2 2 0 0 2 2 2 0 EF-hand domain EF-hand_7 PF13499.6 CBZ27111.1 - 0.076 13.5 1.5 0.38 11.3 0.2 2.2 1 1 2 3 3 3 0 EF-hand domain pair MAM33 PF02330.16 CBZ27113.1 - 2.1e-19 70.3 0.1 2.4e-17 63.6 0.1 2.3 1 1 0 1 1 1 1 Mitochondrial glycoprotein Metallophos PF00149.28 CBZ27114.1 - 3.1e-11 44.2 0.0 4.3e-11 43.7 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase DUF4440 PF14534.6 CBZ27114.1 - 0.046 14.1 0.0 0.095 13.1 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4440) CATSPERB PF15149.6 CBZ27114.1 - 0.061 11.9 0.0 0.082 11.4 0.0 1.1 1 0 0 1 1 1 0 Cation channel sperm-associated protein subunit beta protein family FBPase_2 PF06874.11 CBZ27114.1 - 0.12 10.7 0.1 21 3.2 0.0 2.8 3 0 0 3 3 3 0 Firmicute fructose-1,6-bisphosphatase HA2 PF04408.23 CBZ27115.1 - 6.3e-18 65.0 0.0 1.7e-17 63.6 0.0 1.8 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.31 CBZ27115.1 - 1.2e-15 57.8 0.0 2.7e-15 56.7 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 CBZ27115.1 - 4.8e-08 33.0 0.0 1.3e-07 31.6 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 CBZ27115.1 - 1.6e-06 28.4 0.0 3.9e-06 27.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 CBZ27115.1 - 0.016 15.5 0.0 0.04 14.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 CBZ27115.1 - 0.027 14.0 0.0 1.8 8.1 0.0 2.8 2 0 0 2 2 2 0 AAA domain R3H PF01424.22 CBZ27115.1 - 0.028 14.4 0.0 0.095 12.7 0.0 2.0 1 0 0 1 1 1 0 R3H domain T2SSE PF00437.20 CBZ27115.1 - 0.046 12.8 0.0 0.089 11.8 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_33 PF13671.6 CBZ27115.1 - 0.13 12.5 0.0 0.58 10.3 0.0 2.1 2 0 0 2 2 2 0 AAA domain Ribosomal_L14e PF01929.17 CBZ27117.1 - 6.5e-17 61.8 1.6 6.5e-17 61.8 1.6 2.3 2 1 1 3 3 3 1 Ribosomal protein L14 KOW PF00467.29 CBZ27117.1 - 0.00014 21.7 0.9 0.00026 20.8 0.9 1.5 1 0 0 1 1 1 1 KOW motif CoaE PF01121.20 CBZ27118.1 - 7e-42 143.1 0.0 1.3e-41 142.2 0.0 1.4 1 1 0 1 1 1 1 Dephospho-CoA kinase AAA_18 PF13238.6 CBZ27118.1 - 0.00066 20.2 0.1 0.013 16.0 0.1 2.4 1 1 0 1 1 1 1 AAA domain PRK PF00485.18 CBZ27118.1 - 0.015 15.0 0.1 0.047 13.4 0.0 1.7 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family SKI PF01202.22 CBZ27118.1 - 0.13 12.3 0.0 0.28 11.3 0.0 1.5 1 0 0 1 1 1 0 Shikimate kinase UCR_Fe-S_N PF10399.9 CBZ27118.1 - 1.8 7.9 8.6 6.1 6.3 8.6 1.9 1 0 0 1 1 1 0 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal tRNA-synt_2c PF01411.19 CBZ27119.1 - 6.8e-193 642.1 0.0 9e-193 641.7 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (A) tRNA_SAD PF07973.14 CBZ27119.1 - 8.2e-11 41.8 0.0 2e-10 40.6 0.0 1.7 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain DHHA1 PF02272.19 CBZ27119.1 - 0.0003 21.2 3.8 0.0034 17.8 2.5 3.1 2 1 1 3 3 3 1 DHHA1 domain FliMN_C PF01052.20 CBZ27120.1 - 0.037 14.0 0.0 0.084 12.9 0.0 1.6 1 0 0 1 1 1 0 Type III flagellar switch regulator (C-ring) FliN C-term Ribosomal_L14e PF01929.17 CBZ27121.1 - 6.5e-17 61.8 1.6 6.5e-17 61.8 1.6 2.3 2 1 1 3 3 3 1 Ribosomal protein L14 KOW PF00467.29 CBZ27121.1 - 0.00014 21.7 0.9 0.00026 20.8 0.9 1.5 1 0 0 1 1 1 1 KOW motif RNase_PH PF01138.21 CBZ27123.1 - 5.2e-09 36.7 0.0 1.2e-08 35.6 0.0 1.5 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 CBZ27123.1 - 0.00012 22.0 0.1 0.00029 20.8 0.1 1.6 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 NAD_binding_5 PF07994.12 CBZ27123.1 - 0.15 11.4 0.0 0.23 10.8 0.0 1.2 1 0 0 1 1 1 0 Myo-inositol-1-phosphate synthase Metallophos PF00149.28 CBZ27125.1 - 1.8e-10 41.7 0.0 3.8e-10 40.6 0.0 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 CBZ27125.1 - 9.3e-06 25.9 0.0 1.8e-05 25.0 0.0 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain ASH PF15780.5 CBZ27127.1 - 1.2e-40 137.7 27.8 3.4e-06 27.2 0.0 16.8 17 0 0 17 17 17 9 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin TMEM131_like PF12371.8 CBZ27127.1 - 8.2e-09 35.6 3.9 1.6 9.0 0.1 8.8 10 0 0 10 10 10 2 Transmembrane protein 131-like Motile_Sperm PF00635.26 CBZ27127.1 - 8.6e-09 35.2 0.0 15 5.5 0.0 9.2 11 0 0 11 11 11 1 MSP (Major sperm protein) domain MYCBPAP PF14646.6 CBZ27127.1 - 0.00019 20.5 0.0 0.13 11.2 0.0 4.4 5 0 0 5 5 5 1 MYCBP-associated protein family PapD-like PF14874.6 CBZ27127.1 - 0.00039 20.5 15.5 0.017 15.3 0.1 7.3 7 1 1 8 8 8 2 Flagellar-associated PapD-like Gryzun-like PF12742.7 CBZ27127.1 - 0.018 15.0 0.0 2 8.5 0.0 3.3 3 0 0 3 3 3 0 Gryzun, putative Golgi trafficking CAF1 PF04857.20 CBZ27128.1 - 3.9e-23 82.1 3.8 3e-12 46.3 0.1 2.5 1 1 1 2 2 2 2 CAF1 family ribonuclease cobW PF02492.19 CBZ27130.1 - 1.8e-26 92.8 0.2 2.5e-26 92.3 0.2 1.2 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain AAA_22 PF13401.6 CBZ27130.1 - 0.0072 16.6 0.0 0.015 15.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain CobW_C PF07683.14 CBZ27130.1 - 0.0095 15.8 0.0 0.022 14.6 0.0 1.6 1 0 0 1 1 1 1 Cobalamin synthesis protein cobW C-terminal domain AAA_33 PF13671.6 CBZ27130.1 - 0.0096 16.1 0.0 0.016 15.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain MobB PF03205.14 CBZ27130.1 - 0.01 15.7 0.0 0.018 14.9 0.0 1.4 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B SRP54 PF00448.22 CBZ27130.1 - 0.037 13.6 0.0 0.068 12.8 0.0 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain TrwB_AAD_bind PF10412.9 CBZ27130.1 - 0.073 12.0 0.0 0.11 11.4 0.0 1.2 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain AAA_7 PF12775.7 CBZ27130.1 - 0.089 12.3 0.0 0.15 11.5 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region CBP_BcsQ PF06564.12 CBZ27130.1 - 0.13 11.8 0.0 4.1 6.8 0.0 2.1 2 0 0 2 2 2 0 Cellulose biosynthesis protein BcsQ RINT1_TIP1 PF04437.13 CBZ27131.1 - 0.0028 16.6 0.4 0.0047 15.9 0.0 1.5 2 0 0 2 2 2 1 RINT-1 / TIP-1 family DUF445 PF04286.12 CBZ27135.1 - 0.011 15.6 1.1 0.012 15.5 0.2 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF445) DUF1216 PF06746.11 CBZ27135.1 - 0.2 11.6 2.1 0.15 12.0 0.4 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1216) UTP15_C PF09384.10 CBZ27137.1 - 2.9e-30 104.9 0.4 4.6e-30 104.2 0.4 1.3 1 0 0 1 1 1 1 UTP15 C terminal WD40 PF00400.32 CBZ27137.1 - 6.2e-13 49.0 3.7 0.012 16.4 0.1 5.8 6 0 0 6 6 6 3 WD domain, G-beta repeat AhpC-TSA PF00578.21 CBZ27138.1 - 2e-38 131.1 0.0 2.6e-38 130.8 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 CBZ27138.1 - 5.5e-17 61.9 0.0 6.7e-17 61.6 0.0 1.1 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.9 CBZ27138.1 - 1.7e-08 34.2 0.1 4e-08 33.0 0.1 1.7 2 0 0 2 2 2 1 C-terminal domain of 1-Cys peroxiredoxin SCO1-SenC PF02630.14 CBZ27138.1 - 0.012 15.6 0.1 0.021 14.8 0.1 1.3 1 0 0 1 1 1 0 SCO1/SenC AhpC-TSA_2 PF13911.6 CBZ27138.1 - 0.076 13.1 0.0 0.22 11.6 0.0 1.7 2 1 0 2 2 2 0 AhpC/TSA antioxidant enzyme EIAV_GP90 PF00971.18 CBZ27138.1 - 0.12 11.0 0.0 0.15 10.7 0.0 1.1 1 0 0 1 1 1 0 EIAV coat protein, gp90 Pro_isomerase PF00160.21 CBZ27139.1 - 1.2e-45 155.6 0.0 2.2e-45 154.8 0.0 1.4 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD vATP-synt_E PF01991.18 CBZ27139.1 - 0.23 10.8 5.9 0.34 10.3 5.9 1.2 1 0 0 1 1 1 0 ATP synthase (E/31 kDa) subunit Arginase PF00491.21 CBZ27141.1 - 1.7e-27 96.7 0.0 2.2e-27 96.3 0.0 1.2 1 0 0 1 1 1 1 Arginase family IspD PF01128.19 CBZ27141.1 - 0.054 13.2 0.0 0.086 12.6 0.0 1.2 1 0 0 1 1 1 0 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase Tropomyosin_1 PF12718.7 CBZ27142.1 - 1.5e-05 25.2 3.2 1.5e-05 25.2 3.2 4.4 1 1 2 4 4 4 2 Tropomyosin like FliJ PF02050.16 CBZ27142.1 - 0.0019 18.4 6.0 0.0019 18.4 6.0 4.9 3 2 1 4 4 4 1 Flagellar FliJ protein Lebercilin PF15619.6 CBZ27142.1 - 0.56 9.8 62.0 1.3 8.7 26.5 5.1 4 1 0 4 4 4 0 Ciliary protein causing Leber congenital amaurosis disease RMI1_N PF08585.12 CBZ27143.1 - 1.4e-24 87.0 0.2 8.6e-24 84.5 0.2 1.9 1 1 0 1 1 1 1 RecQ mediated genome instability protein Methyltransf_16 PF10294.9 CBZ27144.1 - 8e-16 58.3 0.0 1.1e-15 57.8 0.0 1.1 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_12 PF08242.12 CBZ27144.1 - 1.4e-08 35.4 0.0 3.9e-08 33.9 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 CBZ27144.1 - 5.3e-08 33.5 0.2 1.1e-07 32.4 0.1 1.6 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CBZ27144.1 - 8.4e-08 32.1 0.1 1.2e-07 31.6 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 CBZ27144.1 - 4.3e-05 23.1 0.1 5.8e-05 22.7 0.1 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_11 PF08241.12 CBZ27144.1 - 0.00022 21.8 0.2 0.00071 20.2 0.1 1.9 2 0 0 2 2 2 1 Methyltransferase domain tRNA_U5-meth_tr PF05958.11 CBZ27144.1 - 0.00073 18.6 0.0 0.0011 18.1 0.0 1.2 1 0 0 1 1 1 1 tRNA (Uracil-5-)-methyltransferase Methyltransf_23 PF13489.6 CBZ27144.1 - 0.0061 16.4 0.0 0.0091 15.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 CBZ27144.1 - 0.012 15.0 0.0 0.015 14.7 0.0 1.1 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) NodS PF05401.11 CBZ27144.1 - 0.054 13.1 0.0 0.085 12.5 0.0 1.3 1 0 0 1 1 1 0 Nodulation protein S (NodS) MethyltransfD12 PF02086.15 CBZ27144.1 - 0.06 13.0 0.0 0.084 12.5 0.0 1.2 1 0 0 1 1 1 0 D12 class N6 adenine-specific DNA methyltransferase Methyltransf_9 PF08003.11 CBZ27144.1 - 0.066 12.1 0.0 0.1 11.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) NTP_transferase PF00483.23 CBZ27145.1 - 4.4e-48 164.0 0.0 6.6e-48 163.5 0.0 1.2 1 0 0 1 1 1 1 Nucleotidyl transferase NTP_transf_3 PF12804.7 CBZ27145.1 - 6.3e-12 46.1 0.0 9.3e-12 45.6 0.0 1.3 1 0 0 1 1 1 1 MobA-like NTP transferase domain Hexapep PF00132.24 CBZ27145.1 - 2e-10 39.9 11.7 4.7e-06 26.1 2.5 3.9 1 1 2 3 3 3 3 Bacterial transferase hexapeptide (six repeats) Fucokinase PF07959.12 CBZ27145.1 - 2.6e-06 26.6 0.4 0.0076 15.2 0.1 2.9 2 1 1 3 3 3 2 L-fucokinase DUF4954 PF16314.5 CBZ27145.1 - 0.0039 15.4 1.4 0.0056 14.9 1.4 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4954) CTP_transf_3 PF02348.19 CBZ27145.1 - 0.089 12.7 0.0 0.13 12.2 0.0 1.2 1 0 0 1 1 1 0 Cytidylyltransferase Hexapep_2 PF14602.6 CBZ27145.1 - 0.092 12.5 16.6 0.045 13.5 1.8 3.9 3 1 1 4 4 4 0 Hexapeptide repeat of succinyl-transferase Beach PF02138.18 CBZ27146.1 - 1.2e-98 329.9 0.0 2.1e-98 329.1 0.0 1.4 1 0 0 1 1 1 1 Beige/BEACH domain Laminin_G_3 PF13385.6 CBZ27146.1 - 5.4e-05 23.4 0.0 0.00019 21.6 0.0 1.9 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily PH_BEACH PF14844.6 CBZ27146.1 - 0.0067 16.5 0.0 0.017 15.2 0.0 1.6 1 0 0 1 1 1 1 PH domain associated with Beige/BEACH Pro_isomerase PF00160.21 CBZ27147.1 - 2.8e-14 53.7 0.0 3.4e-14 53.4 0.0 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD ATP-synt_C PF00137.21 CBZ27148.1 - 5.1e-26 90.8 36.7 1.1e-14 54.4 14.9 2.2 2 0 0 2 2 2 2 ATP synthase subunit C DUF4064 PF13273.6 CBZ27148.1 - 0.47 10.8 15.8 1.8 8.9 8.4 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF4064) GerA PF03323.13 CBZ27148.1 - 2.2 6.7 8.4 2.8 6.3 0.8 2.1 2 0 0 2 2 2 0 Bacillus/Clostridium GerA spore germination protein Abhydrolase_6 PF12697.7 CBZ27149.1 - 1.1e-17 65.4 2.6 1.7e-17 64.8 2.6 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 CBZ27149.1 - 1.6e-14 54.2 0.1 2.8e-14 53.4 0.1 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 CBZ27149.1 - 9.7e-10 38.1 0.0 2.6e-09 36.7 0.0 1.6 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Ser_hydrolase PF06821.13 CBZ27149.1 - 8.6e-05 22.5 0.0 0.0002 21.3 0.0 1.6 1 0 0 1 1 1 1 Serine hydrolase LIDHydrolase PF10230.9 CBZ27149.1 - 0.011 15.3 0.0 0.016 14.8 0.0 1.2 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase Thioesterase PF00975.20 CBZ27149.1 - 0.18 11.9 0.4 0.29 11.2 0.1 1.5 2 0 0 2 2 2 0 Thioesterase domain LRR_6 PF13516.6 CBZ27150.1 - 5.4e-10 38.5 15.2 0.0016 18.3 0.0 9.6 12 0 0 12 12 12 4 Leucine Rich repeat cNMP_binding PF00027.29 CBZ27151.1 - 6.3e-08 32.6 0.2 0.0079 16.2 0.0 2.5 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain FapA PF03961.13 CBZ27152.1 - 0.031 12.9 0.3 0.038 12.6 0.3 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A DUF3287 PF11690.8 CBZ27152.1 - 0.093 12.5 3.6 0.17 11.6 3.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3287) DivIC PF04977.15 CBZ27152.1 - 0.096 12.5 8.4 0.087 12.6 2.5 2.4 1 1 1 2 2 2 0 Septum formation initiator XylR_N PF06505.11 CBZ27152.1 - 0.18 11.6 3.2 0.2 11.4 0.2 2.4 1 1 2 3 3 3 0 Activator of aromatic catabolism TMF_DNA_bd PF12329.8 CBZ27152.1 - 0.32 11.0 6.4 0.23 11.5 1.2 2.2 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding DUF2205 PF10224.9 CBZ27152.1 - 2.1 8.4 11.5 3.6 7.7 0.9 2.6 2 1 0 2 2 2 0 Short coiled-coil protein DUF1525 PF07511.11 CBZ27152.1 - 3.9 7.7 10.4 21 5.3 10.4 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF1525) YqjK PF13997.6 CBZ27152.1 - 5.5 7.3 11.1 2.2 8.6 7.2 2.4 1 1 1 2 2 2 0 YqjK-like protein YjgF_endoribonc PF14588.6 CBZ27155.1 - 1.8e-31 109.3 0.1 2e-31 109.2 0.1 1.0 1 0 0 1 1 1 1 YjgF/chorismate_mutase-like, putative endoribonuclease Ribonuc_L-PSP PF01042.21 CBZ27155.1 - 1.6e-19 70.1 0.1 2.4e-19 69.5 0.1 1.2 1 0 0 1 1 1 1 Endoribonuclease L-PSP ABC_membrane PF00664.23 CBZ27156.1 - 1.5e-57 195.3 32.8 3.9e-35 121.9 10.7 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 CBZ27156.1 - 8.2e-50 168.9 0.0 7.2e-26 91.3 0.0 2.4 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 CBZ27156.1 - 8.3e-09 35.2 0.5 0.18 11.2 0.0 4.2 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 CBZ27156.1 - 6.6e-08 32.2 0.6 0.012 15.3 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.6 CBZ27156.1 - 1.4e-06 28.6 0.1 0.01 16.1 0.0 2.9 2 1 0 2 2 2 2 AAA domain AAA_16 PF13191.6 CBZ27156.1 - 2.8e-06 27.8 0.1 0.0027 18.1 0.0 2.7 2 0 0 2 2 2 1 AAA ATPase domain FtsK_SpoIIIE PF01580.18 CBZ27156.1 - 8e-06 25.4 1.0 0.023 14.1 0.1 2.6 2 0 0 2 2 2 2 FtsK/SpoIIIE family Viral_helicase1 PF01443.18 CBZ27156.1 - 1.5e-05 24.9 0.0 0.0032 17.2 0.0 2.4 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase AAA_21 PF13304.6 CBZ27156.1 - 1.8e-05 24.7 0.0 0.053 13.3 0.0 3.2 4 0 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system T2SSE PF00437.20 CBZ27156.1 - 2.1e-05 23.7 0.0 0.011 14.8 0.0 2.3 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_23 PF13476.6 CBZ27156.1 - 2.7e-05 24.8 0.0 0.086 13.3 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.6 CBZ27156.1 - 3.8e-05 23.3 0.2 0.0068 16.0 0.0 2.7 2 0 0 2 2 2 1 AAA domain DUF87 PF01935.17 CBZ27156.1 - 7e-05 23.0 1.6 0.2 11.7 0.4 2.3 2 0 0 2 2 2 2 Helicase HerA, central domain MMR_HSR1 PF01926.23 CBZ27156.1 - 0.00012 22.1 0.3 0.49 10.5 0.2 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 CBZ27156.1 - 0.00014 21.8 0.6 0.015 15.2 0.1 2.4 2 0 0 2 2 2 1 RsgA GTPase TrwB_AAD_bind PF10412.9 CBZ27156.1 - 0.0016 17.4 0.2 1.1 8.1 0.0 2.3 2 0 0 2 2 2 2 Type IV secretion-system coupling protein DNA-binding domain NACHT PF05729.12 CBZ27156.1 - 0.0021 18.0 3.5 0.13 12.1 0.1 2.7 3 0 0 3 3 2 1 NACHT domain cobW PF02492.19 CBZ27156.1 - 0.0094 15.6 2.5 0.62 9.6 0.1 2.4 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.6 CBZ27156.1 - 0.012 15.8 0.1 1.2 9.3 0.1 2.7 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 CBZ27156.1 - 0.012 15.3 0.2 1.5 8.5 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 CBZ27156.1 - 0.014 14.9 0.3 2.1 7.8 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region Zeta_toxin PF06414.12 CBZ27156.1 - 0.015 14.6 0.0 4.3 6.6 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin RNA_helicase PF00910.22 CBZ27156.1 - 0.016 15.6 0.0 1.9 8.9 0.0 2.6 2 0 0 2 2 2 0 RNA helicase NB-ARC PF00931.22 CBZ27156.1 - 0.02 14.1 0.1 6.5 5.8 0.0 2.3 2 0 0 2 2 2 0 NB-ARC domain Roc PF08477.13 CBZ27156.1 - 0.021 15.0 0.5 8.9 6.6 0.3 2.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_28 PF13521.6 CBZ27156.1 - 0.028 14.6 0.0 0.41 10.9 0.0 2.6 2 0 0 2 2 2 0 AAA domain Pox_A32 PF04665.12 CBZ27156.1 - 0.038 13.4 1.4 4.7 6.6 0.3 2.6 2 0 0 2 2 2 0 Poxvirus A32 protein ATP_bind_1 PF03029.17 CBZ27156.1 - 0.04 13.7 1.0 3.5 7.4 0.0 2.5 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_18 PF13238.6 CBZ27156.1 - 0.043 14.4 0.0 4.4 7.9 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.6 CBZ27156.1 - 0.043 13.8 0.1 2.3 8.2 0.0 2.5 2 0 0 2 2 2 0 AAA domain MeaB PF03308.16 CBZ27156.1 - 0.047 12.7 0.4 7 5.5 0.0 2.3 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_24 PF13479.6 CBZ27156.1 - 0.11 12.2 0.1 4.3 7.0 0.0 2.4 2 0 0 2 2 2 0 AAA domain Ploopntkinase3 PF18751.1 CBZ27156.1 - 0.17 11.7 0.3 11 5.9 0.0 3.0 3 0 0 3 3 3 0 P-loop Nucleotide Kinase3 Dynamin_N PF00350.23 CBZ27156.1 - 0.32 11.0 2.8 4.2 7.4 0.5 2.6 3 0 0 3 3 2 0 Dynamin family ABC_membrane PF00664.23 CBZ27157.1 - 3.8e-57 194.0 31.6 1.8e-28 100.0 10.7 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 CBZ27157.1 - 7.8e-50 169.0 0.0 7.2e-26 91.3 0.0 2.4 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 CBZ27157.1 - 2.3e-08 33.7 0.6 0.18 11.2 0.0 4.2 3 1 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 CBZ27157.1 - 6.6e-08 32.2 0.6 0.012 15.3 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.6 CBZ27157.1 - 3.6e-07 30.5 0.2 0.01 16.1 0.0 3.6 3 1 0 3 3 3 2 AAA domain Viral_helicase1 PF01443.18 CBZ27157.1 - 1.9e-06 27.8 0.1 0.0032 17.2 0.0 3.3 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase AAA_16 PF13191.6 CBZ27157.1 - 2.7e-06 27.9 0.2 0.0028 18.1 0.0 2.8 3 0 0 3 3 2 1 AAA ATPase domain FtsK_SpoIIIE PF01580.18 CBZ27157.1 - 8.5e-06 25.3 1.0 0.023 14.1 0.1 2.5 2 0 0 2 2 2 2 FtsK/SpoIIIE family T2SSE PF00437.20 CBZ27157.1 - 1.7e-05 24.0 0.0 0.011 14.8 0.0 2.4 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_21 PF13304.6 CBZ27157.1 - 2.8e-05 24.1 0.0 0.053 13.3 0.0 3.0 4 0 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 CBZ27157.1 - 2.9e-05 24.7 0.0 0.086 13.3 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.6 CBZ27157.1 - 6.2e-05 22.7 1.4 0.0064 16.1 0.0 2.9 3 0 0 3 3 3 1 AAA domain DUF87 PF01935.17 CBZ27157.1 - 6.5e-05 23.1 1.6 0.2 11.7 0.4 2.3 2 0 0 2 2 2 2 Helicase HerA, central domain MMR_HSR1 PF01926.23 CBZ27157.1 - 0.00012 22.1 0.3 0.49 10.5 0.2 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 CBZ27157.1 - 0.00014 21.8 0.6 0.015 15.2 0.1 2.4 2 0 0 2 2 2 1 RsgA GTPase NACHT PF05729.12 CBZ27157.1 - 0.00044 20.2 0.8 0.13 12.1 0.1 2.5 2 0 0 2 2 2 1 NACHT domain TrwB_AAD_bind PF10412.9 CBZ27157.1 - 0.0018 17.3 0.2 1.1 8.1 0.0 2.2 2 0 0 2 2 2 2 Type IV secretion-system coupling protein DNA-binding domain AAA_30 PF13604.6 CBZ27157.1 - 0.0079 15.9 0.2 1.5 8.5 0.0 2.8 2 0 0 2 2 2 1 AAA domain cobW PF02492.19 CBZ27157.1 - 0.0086 15.7 2.5 0.62 9.6 0.1 2.5 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.6 CBZ27157.1 - 0.011 15.9 0.1 1.2 9.3 0.1 2.8 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 CBZ27157.1 - 0.011 15.1 0.0 4.3 6.6 0.0 2.7 2 0 0 2 2 2 0 Zeta toxin AAA_7 PF12775.7 CBZ27157.1 - 0.012 15.1 0.3 2.1 7.8 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region RNA_helicase PF00910.22 CBZ27157.1 - 0.015 15.7 0.0 1.9 8.9 0.0 2.7 2 0 0 2 2 2 0 RNA helicase Roc PF08477.13 CBZ27157.1 - 0.017 15.4 0.5 8.9 6.6 0.3 2.8 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase NB-ARC PF00931.22 CBZ27157.1 - 0.019 14.2 0.1 6.6 5.8 0.0 2.4 2 0 0 2 2 2 0 NB-ARC domain AAA_28 PF13521.6 CBZ27157.1 - 0.027 14.7 0.0 0.41 10.9 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.6 CBZ27157.1 - 0.042 13.9 0.1 2.3 8.2 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 CBZ27157.1 - 0.046 14.3 0.0 4.4 7.9 0.0 2.5 2 0 0 2 2 2 0 AAA domain Pox_A32 PF04665.12 CBZ27157.1 - 0.046 13.2 1.4 4.7 6.6 0.3 2.4 2 0 0 2 2 2 0 Poxvirus A32 protein MeaB PF03308.16 CBZ27157.1 - 0.047 12.7 0.4 7 5.5 0.0 2.3 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_24 PF13479.6 CBZ27157.1 - 0.099 12.4 0.2 4.3 7.0 0.0 2.6 3 0 0 3 3 2 0 AAA domain ATP_bind_1 PF03029.17 CBZ27157.1 - 0.41 10.4 5.2 3.5 7.4 0.0 3.0 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein Dynamin_N PF00350.23 CBZ27157.1 - 0.47 10.5 3.2 4.2 7.4 0.5 2.5 2 0 0 2 2 2 0 Dynamin family BatD PF13584.6 CBZ27160.1 - 0.016 14.0 0.1 0.02 13.7 0.1 1.1 1 0 0 1 1 1 0 Oxygen tolerance WBP-1 PF11669.8 CBZ27160.1 - 0.045 14.4 0.4 0.092 13.4 0.4 1.6 1 0 0 1 1 1 0 WW domain-binding protein 1 Yip1 PF04893.17 CBZ27161.1 - 1.2e-16 60.9 16.8 1.2e-16 60.9 16.8 1.3 1 1 0 1 1 1 1 Yip1 domain DUF1282 PF06930.12 CBZ27161.1 - 0.24 11.2 12.8 0.35 10.6 12.6 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1282) ABC_membrane PF00664.23 CBZ27162.1 - 1.3e-70 238.2 26.5 1.8e-35 122.9 4.8 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 CBZ27162.1 - 7.5e-50 169.0 0.0 7.3e-26 91.3 0.0 2.6 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 CBZ27162.1 - 1.8e-08 34.1 0.9 0.18 11.2 0.0 4.3 3 1 1 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 CBZ27162.1 - 2.2e-08 33.7 0.3 0.0043 16.8 0.1 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.6 CBZ27162.1 - 7.4e-06 26.3 0.3 0.074 13.3 0.0 3.3 3 1 0 3 3 2 2 AAA domain FtsK_SpoIIIE PF01580.18 CBZ27162.1 - 8.2e-06 25.4 0.5 0.031 13.7 0.1 2.5 2 0 0 2 2 2 2 FtsK/SpoIIIE family AAA_25 PF13481.6 CBZ27162.1 - 1.2e-05 25.0 0.1 0.0018 17.9 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 CBZ27162.1 - 7.6e-05 23.2 0.3 0.13 12.6 0.0 3.1 3 0 0 3 3 3 1 AAA ATPase domain MMR_HSR1 PF01926.23 CBZ27162.1 - 0.0001 22.3 0.3 0.49 10.5 0.2 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_21 PF13304.6 CBZ27162.1 - 0.00013 21.9 0.3 0.93 9.2 0.4 3.4 3 1 1 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 CBZ27162.1 - 0.00018 21.4 0.4 0.024 14.5 0.0 2.5 2 0 0 2 2 2 1 RsgA GTPase AAA_23 PF13476.6 CBZ27162.1 - 0.00018 22.0 0.2 0.5 10.8 0.1 2.3 2 0 0 2 2 2 2 AAA domain T2SSE PF00437.20 CBZ27162.1 - 0.00027 20.1 0.1 0.17 11.0 0.0 2.4 2 0 0 2 2 2 2 Type II/IV secretion system protein DUF87 PF01935.17 CBZ27162.1 - 0.0004 20.5 1.5 0.66 10.0 0.0 2.3 2 0 0 2 2 2 2 Helicase HerA, central domain NACHT PF05729.12 CBZ27162.1 - 0.0031 17.4 0.9 0.9 9.4 0.1 2.5 2 0 0 2 2 2 1 NACHT domain CAP_GLY PF01302.25 CBZ27162.1 - 0.0031 17.5 0.0 0.011 15.8 0.0 1.9 1 0 0 1 1 1 1 CAP-Gly domain AAA_7 PF12775.7 CBZ27162.1 - 0.0035 16.9 0.3 0.52 9.8 0.1 2.3 2 0 0 2 2 2 1 P-loop containing dynein motor region Viral_helicase1 PF01443.18 CBZ27162.1 - 0.0055 16.5 0.0 1.3 8.8 0.0 2.4 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase TrwB_AAD_bind PF10412.9 CBZ27162.1 - 0.0056 15.6 0.9 2.3 7.1 0.1 2.2 2 0 0 2 2 2 2 Type IV secretion-system coupling protein DNA-binding domain AAA_33 PF13671.6 CBZ27162.1 - 0.0069 16.6 0.3 0.78 9.9 0.2 2.8 2 0 0 2 2 2 1 AAA domain cobW PF02492.19 CBZ27162.1 - 0.016 14.8 0.3 4.4 6.9 0.0 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Dynamin_N PF00350.23 CBZ27162.1 - 0.021 14.9 0.5 0.71 9.9 0.0 2.3 2 0 0 2 2 2 0 Dynamin family RNA_helicase PF00910.22 CBZ27162.1 - 0.025 14.9 0.0 3.4 8.1 0.0 2.7 2 0 0 2 2 2 0 RNA helicase Roc PF08477.13 CBZ27162.1 - 0.031 14.5 0.6 8.9 6.6 0.3 2.5 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_30 PF13604.6 CBZ27162.1 - 0.035 13.8 0.3 4.3 7.0 0.0 2.5 2 0 0 2 2 2 0 AAA domain Ploopntkinase3 PF18751.1 CBZ27162.1 - 0.06 13.3 0.7 1.4 8.8 0.0 2.7 3 0 0 3 3 2 0 P-loop Nucleotide Kinase3 DLIC PF05783.11 CBZ27162.1 - 0.11 11.3 0.0 0.2 10.4 0.0 1.3 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) AAA_14 PF13173.6 CBZ27162.1 - 0.11 12.5 0.2 6.3 6.8 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 CBZ27162.1 - 0.15 12.6 0.0 16 6.0 0.0 2.6 2 0 0 2 2 2 0 AAA domain Septin PF00735.18 CBZ27162.1 - 0.15 11.3 0.5 1.8 7.7 0.0 2.1 2 0 0 2 2 2 0 Septin AAA_24 PF13479.6 CBZ27162.1 - 0.17 11.6 0.2 4.3 7.0 0.0 2.4 2 0 0 2 2 2 0 AAA domain ATP_bind_1 PF03029.17 CBZ27162.1 - 0.19 11.5 2.5 5.4 6.7 0.2 2.4 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein PduV-EutP PF10662.9 CBZ27162.1 - 0.2 11.4 1.5 8.5 6.1 0.1 3.5 4 0 0 4 4 4 0 Ethanolamine utilisation - propanediol utilisation NB-ARC PF00931.22 CBZ27162.1 - 0.34 10.0 1.5 7.4 5.7 0.1 2.6 3 0 0 3 3 3 0 NB-ARC domain Zeta_toxin PF06414.12 CBZ27162.1 - 2.7 7.2 5.4 10 5.3 0.1 2.8 3 0 0 3 3 3 0 Zeta toxin Arginosuc_synth PF00764.19 CBZ27163.1 - 2.6e-149 497.8 0.0 3e-149 497.6 0.0 1.0 1 0 0 1 1 1 1 Arginosuccinate synthase QueC PF06508.13 CBZ27163.1 - 0.17 11.3 0.0 0.28 10.7 0.0 1.3 1 0 0 1 1 1 0 Queuosine biosynthesis protein QueC adh_short_C2 PF13561.6 CBZ27164.1 - 4.4e-33 114.8 0.5 2.2e-30 106.0 0.5 2.6 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 CBZ27164.1 - 6.2e-26 91.1 0.0 7.1e-16 58.2 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase Epimerase PF01370.21 CBZ27164.1 - 0.0029 17.1 0.0 0.034 13.6 0.0 2.0 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family KR PF08659.10 CBZ27164.1 - 0.11 12.4 0.2 0.25 11.2 0.2 1.5 1 0 0 1 1 1 0 KR domain zf-C3HC4 PF00097.25 CBZ27165.1 - 1.6e-06 27.9 7.4 4.3e-06 26.5 7.4 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CBZ27165.1 - 4.8e-05 23.3 7.2 4.8e-05 23.3 7.2 2.0 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_5 PF14634.6 CBZ27165.1 - 0.0023 17.8 7.3 0.0064 16.4 7.3 1.8 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 CBZ27165.1 - 0.0069 16.5 8.9 0.016 15.4 8.9 1.7 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.6 CBZ27165.1 - 0.0093 15.8 8.1 0.0093 15.8 8.1 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) TF_Zn_Ribbon PF08271.12 CBZ27165.1 - 0.089 12.3 5.7 0.27 10.8 5.7 1.8 1 0 0 1 1 1 0 TFIIB zinc-binding zf-RING_2 PF13639.6 CBZ27165.1 - 0.29 11.5 8.4 0.91 9.9 8.4 1.9 1 0 0 1 1 1 0 Ring finger domain zf-ZPR1 PF03367.13 CBZ27165.1 - 0.35 10.7 1.7 6.2 6.7 0.0 2.8 3 0 0 3 3 3 0 ZPR1 zinc-finger domain zf-RING_6 PF14835.6 CBZ27165.1 - 0.59 10.0 6.7 4.8 7.1 6.7 2.3 1 1 0 1 1 1 0 zf-RING of BARD1-type protein UCR_14kD PF02271.16 CBZ27165.1 - 3.6 7.6 5.7 1.5 8.8 0.9 2.4 2 0 0 2 2 2 0 Ubiquinol-cytochrome C reductase complex 14kD subunit Prok-RING_4 PF14447.6 CBZ27165.1 - 3.9 7.4 6.9 17 5.4 6.8 2.1 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 Hus1 PF04005.12 CBZ27166.1 - 9.9e-87 290.7 0.0 1.1e-86 290.6 0.0 1.0 1 0 0 1 1 1 1 Hus1-like protein tRNA-synt_1b PF00579.25 CBZ27167.1 - 6.1e-18 65.2 0.0 1.6e-17 63.8 0.0 1.6 1 1 0 1 1 1 1 tRNA synthetases class I (W and Y) DUF3729 PF12526.8 CBZ27167.1 - 0.57 11.8 3.4 1.1 10.8 3.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3729) AAA_16 PF13191.6 CBZ27168.1 - 0.0015 18.9 0.0 0.004 17.6 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain ABC_tran PF00005.27 CBZ27168.1 - 0.0058 17.2 0.0 0.012 16.1 0.0 1.5 1 0 0 1 1 1 1 ABC transporter tRNA_lig_kinase PF08303.11 CBZ27168.1 - 0.01 15.9 0.0 0.084 13.0 0.0 2.1 1 1 0 1 1 1 0 tRNA ligase kinase domain AAA_5 PF07728.14 CBZ27168.1 - 0.013 15.5 0.0 0.027 14.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 CBZ27168.1 - 0.02 15.4 0.0 0.071 13.6 0.0 2.0 2 0 0 2 2 1 0 AAA domain RuvB_N PF05496.12 CBZ27168.1 - 0.039 13.7 0.0 0.086 12.6 0.0 1.5 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_33 PF13671.6 CBZ27168.1 - 0.047 13.9 0.8 0.099 12.8 0.0 2.0 2 0 0 2 2 2 0 AAA domain Mg_chelatase PF01078.21 CBZ27168.1 - 0.061 12.7 0.0 0.24 10.8 0.0 1.9 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA PF00004.29 CBZ27168.1 - 0.066 13.6 0.0 0.16 12.4 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 CBZ27168.1 - 0.071 13.5 0.0 0.15 12.4 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_22 PF13401.6 CBZ27168.1 - 0.094 13.0 0.0 0.22 11.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_15 PF13175.6 CBZ27168.1 - 0.12 12.1 0.0 0.17 11.5 0.0 1.1 1 0 0 1 1 1 0 AAA ATPase domain Sporozoite_P67 PF05642.11 CBZ27168.1 - 6 4.8 9.9 5.1 5.1 0.3 2.4 2 0 0 2 2 2 0 Sporozoite P67 surface antigen Trypan_glycop PF00913.19 CBZ27169.1 - 0.031 13.6 0.1 0.036 13.3 0.1 1.1 1 0 0 1 1 1 0 Trypanosome variant surface glycoprotein (A-type) V-ATPase_G PF03179.15 CBZ27171.1 - 2e-21 76.5 13.9 2.2e-21 76.4 13.9 1.0 1 0 0 1 1 1 1 Vacuolar (H+)-ATPase G subunit FAM193_C PF15914.5 CBZ27171.1 - 0.1 12.4 1.8 0.55 10.0 0.1 2.6 2 1 1 3 3 3 0 FAM193 family C-terminal ArAE_2_N PF10337.9 CBZ27171.1 - 0.28 10.2 3.5 0.31 10.0 3.5 1.0 1 0 0 1 1 1 0 Putative ER transporter, 6TM, N-terminal ADH_N PF08240.12 CBZ27174.1 - 1.8e-26 92.2 8.6 1.8e-26 92.2 8.6 1.7 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 CBZ27174.1 - 7.1e-23 81.0 0.0 1.5e-22 80.0 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 CBZ27174.1 - 2.8e-07 30.0 0.2 4.4e-07 29.4 0.2 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.19 CBZ27174.1 - 2e-06 27.3 0.1 3.3e-06 26.6 0.1 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ADH_zinc_N_2 PF13602.6 CBZ27174.1 - 2.7e-05 25.2 0.0 4.8e-05 24.4 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 CBZ27174.1 - 5.4e-05 22.8 0.3 8.7e-05 22.1 0.3 1.2 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus NAD_binding_2 PF03446.15 CBZ27174.1 - 0.00029 21.1 0.6 0.00055 20.1 0.6 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase Shikimate_DH PF01488.20 CBZ27174.1 - 0.0013 18.8 0.3 0.0035 17.4 0.1 1.7 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase 3HCDH_N PF02737.18 CBZ27174.1 - 0.0013 18.6 0.4 0.0021 17.9 0.4 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain adh_short PF00106.25 CBZ27174.1 - 0.0035 16.8 0.1 0.098 12.1 0.4 2.5 2 1 0 2 2 2 1 short chain dehydrogenase TrkA_N PF02254.18 CBZ27174.1 - 0.11 12.8 0.1 0.2 12.0 0.1 1.4 1 0 0 1 1 1 0 TrkA-N domain ApbA PF02558.16 CBZ27174.1 - 0.11 12.1 0.2 0.26 10.9 0.2 1.6 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA ABC_tran PF00005.27 CBZ27176.1 - 4.8e-30 104.9 0.0 9.2e-30 103.9 0.0 1.5 1 0 0 1 1 1 1 ABC transporter ABC2_membrane PF01061.24 CBZ27176.1 - 1.7e-24 86.4 16.3 1.7e-24 86.4 16.3 2.9 4 0 0 4 4 4 1 ABC-2 type transporter AAA_21 PF13304.6 CBZ27176.1 - 0.00057 19.8 0.0 0.25 11.1 0.1 2.3 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 CBZ27176.1 - 0.00072 20.0 0.1 0.0021 18.5 0.1 1.8 1 0 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 CBZ27176.1 - 0.00092 18.9 0.0 0.0025 17.5 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 CBZ27176.1 - 0.0021 18.0 0.1 0.0047 16.8 0.1 1.5 1 0 0 1 1 1 1 RsgA GTPase AAA_23 PF13476.6 CBZ27176.1 - 0.0054 17.3 0.1 0.011 16.3 0.1 1.4 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 CBZ27176.1 - 0.015 15.5 0.0 0.034 14.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 CBZ27176.1 - 0.036 14.6 0.1 0.081 13.5 0.1 1.6 1 0 0 1 1 1 0 AAA domain Rad17 PF03215.15 CBZ27176.1 - 0.054 13.4 0.0 0.099 12.6 0.0 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_30 PF13604.6 CBZ27176.1 - 0.073 12.8 0.1 0.13 11.9 0.1 1.3 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 CBZ27176.1 - 0.14 12.1 0.1 0.29 11.1 0.1 1.5 1 0 0 1 1 1 0 NACHT domain DUF1772 PF08592.11 CBZ27176.1 - 0.16 12.3 0.1 0.16 12.3 0.1 3.3 4 0 0 4 4 4 0 Domain of unknown function (DUF1772) AAA_28 PF13521.6 CBZ27176.1 - 0.16 12.2 0.3 0.38 11.0 0.3 1.6 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 CBZ27176.1 - 0.36 10.4 1.8 0.35 10.4 0.2 1.7 2 0 0 2 2 2 0 AAA domain Wzy_C PF04932.15 CBZ27176.1 - 4.5 6.9 5.6 4.6 6.9 0.1 2.9 3 0 0 3 3 3 0 O-Antigen ligase Nterm_IS4 PF13006.7 CBZ27178.1 - 0.041 14.1 1.1 3.7 7.8 0.1 2.9 2 0 0 2 2 2 0 Insertion element 4 transposase N-terminal Aldose_epim PF01263.20 CBZ27180.1 - 1.4e-54 185.5 0.0 2.6e-53 181.3 0.0 2.0 1 1 0 1 1 1 1 Aldose 1-epimerase FtsX PF02687.21 CBZ27182.1 - 4.5e-14 52.7 23.3 1.8e-09 37.9 10.8 7.0 7 1 0 7 7 7 2 FtsX-like permease family CHAP PF05257.16 CBZ27183.1 - 5.5e-11 42.9 0.7 3e-10 40.5 0.7 2.1 1 1 0 1 1 1 1 CHAP domain DUF1664 PF07889.12 CBZ27185.1 - 0.003 17.6 7.0 0.003 17.6 7.0 11.9 8 4 5 14 14 14 6 Protein of unknown function (DUF1664) AMPKBI PF04739.15 CBZ27186.1 - 2.7e-14 53.2 1.9 2.7e-14 53.2 1.9 1.9 2 0 0 2 2 2 1 5'-AMP-activated protein kinase beta subunit, interaction domain AMPK1_CBM PF16561.5 CBZ27186.1 - 1.9e-08 34.4 0.0 3.3e-08 33.6 0.0 1.3 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase ABC_membrane_2 PF06472.15 CBZ27187.1 - 0.16 11.3 2.8 1.1 8.6 0.2 2.2 2 0 0 2 2 2 0 ABC transporter transmembrane region 2 Ribosomal_60s PF00428.19 CBZ27187.1 - 0.64 10.6 0.0 0.64 10.6 0.0 2.7 3 0 0 3 3 3 0 60s Acidic ribosomal protein SET PF00856.28 CBZ27189.1 - 7.8e-13 49.1 0.0 5.2e-12 46.5 0.0 2.0 1 1 0 1 1 1 1 SET domain FtsJ PF01728.19 CBZ27190.1 - 2.2e-47 161.5 0.0 2.6e-47 161.2 0.0 1.1 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_23 PF13489.6 CBZ27190.1 - 0.021 14.7 0.0 0.029 14.2 0.0 1.4 1 1 0 1 1 1 0 Methyltransferase domain AMP-binding PF00501.28 CBZ27191.1 - 3.6e-87 292.7 0.2 4.4e-87 292.4 0.2 1.1 1 0 0 1 1 1 1 AMP-binding enzyme ACAS_N PF16177.5 CBZ27191.1 - 2.6e-18 65.7 3.6 6.5e-18 64.4 3.6 1.7 1 0 0 1 1 1 1 Acetyl-coenzyme A synthetase N-terminus AMP-binding_C PF13193.6 CBZ27191.1 - 1.9e-17 64.0 0.5 3.7e-17 63.1 0.5 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain EF-hand_6 PF13405.6 CBZ27192.1 - 1.4e-08 34.0 0.0 0.0076 16.1 0.0 2.7 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.32 CBZ27192.1 - 2.8e-05 23.4 0.1 0.0047 16.4 0.0 2.5 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 CBZ27192.1 - 6.6e-05 23.3 0.0 0.00027 21.3 0.0 2.0 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_8 PF13833.6 CBZ27192.1 - 0.00023 20.9 1.3 0.24 11.3 0.2 2.9 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.6 CBZ27192.1 - 0.0017 17.7 0.1 0.85 9.2 0.0 2.5 2 0 0 2 2 2 2 EF hand XRN_N PF03159.18 CBZ27193.1 - 5.6e-60 202.8 0.0 1e-59 201.9 0.0 1.5 1 0 0 1 1 1 1 XRN 5'-3' exonuclease N-terminus XRN_M PF17846.1 CBZ27193.1 - 2.9e-07 29.8 10.7 0.00018 20.6 0.0 3.6 4 0 0 4 4 4 3 Xrn1 helical domain CtIP_N PF10482.9 CBZ27194.1 - 0.59 10.2 2.8 1.3 9.0 1.0 2.1 2 0 0 2 2 2 0 Tumour-suppressor protein CtIP N-terminal domain Laminin_II PF06009.12 CBZ27194.1 - 0.67 10.0 4.8 2 8.4 1.9 2.3 1 1 1 2 2 2 0 Laminin Domain II DUF4972 PF16342.5 CBZ27194.1 - 0.97 9.1 4.8 2.4 7.9 0.9 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4972) Atg14 PF10186.9 CBZ27194.1 - 6.4 5.8 6.7 7.4 5.6 5.7 1.5 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 GFO_IDH_MocA PF01408.22 CBZ27195.1 - 2.4e-11 44.5 0.5 1.8e-10 41.7 0.0 2.4 2 1 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold F420_oxidored PF03807.17 CBZ27195.1 - 0.0058 17.2 0.1 0.033 14.8 0.1 2.3 1 1 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Rossmann-like PF10727.9 CBZ27195.1 - 0.013 15.3 0.6 0.14 12.1 0.2 2.5 1 1 0 2 2 2 0 Rossmann-like domain CoA_binding_3 PF13727.6 CBZ27195.1 - 0.15 12.1 0.0 0.3 11.1 0.0 1.5 1 0 0 1 1 1 0 CoA-binding domain GFO_IDH_MocA PF01408.22 CBZ27196.1 - 6.8e-14 52.7 0.2 1.1e-13 52.0 0.2 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold CAF1 PF04857.20 CBZ27199.1 - 3.1e-71 240.2 0.0 3.9e-71 239.8 0.0 1.1 1 0 0 1 1 1 1 CAF1 family ribonuclease CALM_bind PF16025.5 CBZ27199.1 - 0.0012 19.2 0.2 0.0027 18.1 0.2 1.5 1 0 0 1 1 1 1 Calcium-dependent calmodulin binding Kelch_5 PF13854.6 CBZ27200.1 - 1.5e-12 47.2 7.8 0.0019 18.2 0.1 5.1 4 0 0 4 4 4 3 Kelch motif Kelch_4 PF13418.6 CBZ27200.1 - 2.3e-12 46.7 4.1 0.00091 19.2 0.0 6.3 6 0 0 6 6 6 2 Galactose oxidase, central domain Kelch_3 PF13415.6 CBZ27200.1 - 2.2e-08 34.2 12.3 1.4e-05 25.2 0.2 6.4 5 1 0 5 5 5 1 Galactose oxidase, central domain Kelch_6 PF13964.6 CBZ27200.1 - 1.8e-07 31.2 5.1 0.51 10.7 0.1 5.3 5 0 0 5 5 5 3 Kelch motif Kelch_2 PF07646.15 CBZ27200.1 - 2.7e-06 27.1 4.0 8.7 6.5 0.3 5.1 4 1 0 4 4 4 4 Kelch motif Kelch_1 PF01344.25 CBZ27200.1 - 2.4e-05 23.8 8.0 0.0021 17.6 0.1 5.0 4 1 0 4 4 4 1 Kelch motif tRNA_bind PF01588.20 CBZ27201.1 - 4.7e-13 49.1 0.6 6e-13 48.7 0.6 1.1 1 0 0 1 1 1 1 Putative tRNA binding domain zf-RanBP PF00641.18 CBZ27201.1 - 8.7e-06 25.0 1.4 1.5e-05 24.2 1.4 1.3 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others DZR PF12773.7 CBZ27201.1 - 0.02 14.9 1.2 0.035 14.1 1.2 1.5 1 0 0 1 1 1 0 Double zinc ribbon zinc_ribbon_2 PF13240.6 CBZ27201.1 - 0.088 12.6 4.3 0.18 11.6 4.3 1.5 1 0 0 1 1 1 0 zinc-ribbon domain Cu2_monoox_C PF03712.15 CBZ27201.1 - 0.19 11.2 0.4 0.26 10.8 0.4 1.3 1 1 0 1 1 1 0 Copper type II ascorbate-dependent monooxygenase, C-terminal domain zf-ribbon_3 PF13248.6 CBZ27201.1 - 0.21 11.1 2.5 0.47 9.9 2.5 1.6 1 0 0 1 1 1 0 zinc-ribbon domain Lactamase_B PF00753.27 CBZ27202.1 - 1.9e-08 34.6 0.6 1.6e-06 28.3 0.2 2.3 2 0 0 2 2 2 2 Metallo-beta-lactamase superfamily PAP2 PF01569.21 CBZ27203.1 - 5e-08 32.8 7.8 1.7e-07 31.1 4.1 2.7 2 1 0 2 2 2 1 PAP2 superfamily DUF212 PF02681.14 CBZ27203.1 - 0.041 14.0 0.3 9.4 6.4 0.1 2.3 2 0 0 2 2 2 0 Divergent PAP2 family ThiF PF00899.21 CBZ27204.1 - 3.6e-86 288.5 0.2 4.3e-63 212.9 0.0 2.4 2 0 0 2 2 2 2 ThiF family UBA_e1_thiolCys PF10585.9 CBZ27204.1 - 7.7e-68 229.1 1.3 1.1e-67 228.6 1.3 1.2 1 0 0 1 1 1 1 Ubiquitin-activating enzyme active site E1_UFD PF09358.10 CBZ27204.1 - 1e-12 48.6 0.0 2.1e-12 47.6 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin fold domain E1_4HB PF16191.5 CBZ27204.1 - 0.00094 19.3 0.5 0.0024 18.0 0.1 2.0 2 0 0 2 2 2 1 Ubiquitin-activating enzyme E1 four-helix bundle E1_FCCH PF16190.5 CBZ27204.1 - 0.0022 18.1 0.1 0.0068 16.6 0.0 1.8 2 0 0 2 2 2 1 Ubiquitin-activating enzyme E1 FCCH domain Shikimate_DH PF01488.20 CBZ27204.1 - 0.0032 17.5 0.3 1.7 8.7 0.0 2.6 2 0 0 2 2 2 2 Shikimate / quinate 5-dehydrogenase Kinesin PF00225.23 CBZ27205.1 - 1.3e-87 293.8 0.0 2.6e-87 292.8 0.0 1.5 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 CBZ27205.1 - 4e-15 56.0 0.1 1.6e-14 54.1 0.0 2.1 2 0 0 2 2 2 1 Microtubule binding Csm1_N PF18504.1 CBZ27205.1 - 0.07 13.5 18.1 0.14 12.5 0.3 3.8 2 1 1 3 3 3 0 Csm1 N-terminal domain Fib_alpha PF08702.10 CBZ27205.1 - 3.1 8.0 10.7 4.4 7.5 0.4 2.7 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family CREPT PF16566.5 CBZ27205.1 - 7.4 6.7 14.3 4.7 7.4 0.4 3.0 3 0 0 3 3 3 0 Cell-cycle alteration and expression-elevated protein in tumour UPF0184 PF03670.13 CBZ27205.1 - 8.8 6.8 8.1 6.1 7.3 0.1 3.4 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0184) FliD_N PF02465.18 CBZ27205.1 - 9.4 7.0 11.2 2.6 8.8 0.5 3.4 3 0 0 3 3 3 0 Flagellar hook-associated protein 2 N-terminus MYCBPAP PF14646.6 CBZ27206.1 - 6.9e-12 45.0 1.5 1.7e-09 37.2 0.0 2.8 2 1 0 2 2 2 2 MYCBP-associated protein family DUF4083 PF13314.6 CBZ27209.1 - 0.49 10.4 2.5 4.8 7.2 0.2 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4083) TMEM192 PF14802.6 CBZ27209.1 - 0.75 8.8 2.4 1.1 8.3 2.4 1.2 1 0 0 1 1 1 0 TMEM192 family HemY_N PF07219.13 CBZ27209.1 - 7.9 6.7 10.4 0.32 11.2 2.0 2.5 2 1 1 3 3 3 0 HemY protein N-terminus CysA_C_terminal PF17850.1 CBZ27210.1 - 3.7 8.2 0.0 3.7 8.2 0.0 3.7 4 0 0 4 4 4 0 CysA C-terminal regulatory domain BING4CT PF08149.11 CBZ27211.1 - 1.2e-29 102.0 0.2 1.7e-28 98.2 0.0 2.6 3 0 0 3 3 3 1 BING4CT (NUC141) domain WD40 PF00400.32 CBZ27211.1 - 2.1e-06 28.4 1.8 1.6e-05 25.5 0.0 3.1 3 0 0 3 3 3 1 WD domain, G-beta repeat Sec10 PF07393.11 CBZ27212.1 - 1.7e-29 102.8 7.3 2.6e-26 92.3 0.1 3.2 3 0 0 3 3 3 3 Exocyst complex component Sec10 Spc7 PF08317.11 CBZ27212.1 - 6.4 5.6 7.5 2.1 7.1 4.3 1.8 2 0 0 2 2 2 0 Spc7 kinetochore protein Staph_haemo PF05480.11 CBZ27213.1 - 0.11 12.3 0.7 0.23 11.2 0.7 1.5 1 0 0 1 1 1 0 Staphylococcus haemolytic protein Mucin PF01456.17 CBZ27213.1 - 0.35 10.8 4.7 2 8.4 0.7 2.4 2 0 0 2 2 2 0 Mucin-like glycoprotein PalH PF08733.10 CBZ27213.1 - 7.4 5.5 6.3 0.52 9.3 0.1 2.1 3 0 0 3 3 3 0 PalH/RIM21 DIM1 PF02966.16 CBZ27214.1 - 1.1e-30 106.2 0.2 2e-26 92.4 0.1 2.1 2 0 0 2 2 2 2 Mitosis protein DIM1 DUF5320 PF17253.2 CBZ27215.1 - 0.0058 17.7 0.6 0.0058 17.7 0.6 3.6 4 0 0 4 4 4 1 Family of unknown function (DUF5320) GFO_IDH_MocA PF01408.22 CBZ27216.1 - 1.6e-12 48.3 0.1 2.8e-12 47.5 0.1 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold Pyrid_ox_like PF16242.5 CBZ27216.1 - 0.0082 15.7 0.1 0.014 15.0 0.1 1.4 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase like YokU PF14122.6 CBZ27216.1 - 0.13 12.2 0.0 0.36 10.9 0.0 1.7 1 0 0 1 1 1 0 YokU-like protein, putative antitoxin PriCT_2 PF08707.11 CBZ27217.1 - 5.6e-17 61.9 2.7 5.6e-17 61.9 2.7 2.0 2 0 0 2 2 2 1 Primase C terminal 2 (PriCT-2) PPL5 PF18168.1 CBZ27217.1 - 1.2e-08 34.6 7.1 2e-05 24.0 0.0 3.2 3 0 0 3 3 3 2 Prim-pol family 5 DNA_primase_S PF01896.19 CBZ27217.1 - 0.096 12.7 0.0 0.16 12.0 0.0 1.3 1 0 0 1 1 1 0 DNA primase small subunit Thiolase_N PF00108.23 CBZ27218.1 - 3.9e-14 52.6 5.9 7.2e-14 51.8 3.3 2.4 2 1 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 CBZ27218.1 - 8.8e-13 48.0 0.1 8e-11 41.7 0.1 2.5 1 1 1 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 CBZ27218.1 - 1.5e-07 31.3 0.6 3.2e-07 30.2 0.3 1.7 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.10 CBZ27218.1 - 0.023 14.6 1.7 0.85 9.5 1.0 2.8 2 1 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Ketoacyl-synt_C PF02801.22 CBZ27218.1 - 0.24 11.4 3.7 8.7 6.4 0.0 3.4 4 0 0 4 4 4 0 Beta-ketoacyl synthase, C-terminal domain COX17 PF05051.13 CBZ27219.1 - 8.4e-06 26.1 0.3 1.3e-05 25.5 0.3 1.3 1 0 0 1 1 1 1 Cytochrome C oxidase copper chaperone (COX17) AMP-binding PF00501.28 CBZ27220.1 - 8.8e-86 288.1 0.1 1.1e-85 287.8 0.1 1.1 1 0 0 1 1 1 1 AMP-binding enzyme ACAS_N PF16177.5 CBZ27220.1 - 2.6e-18 65.7 3.6 6.3e-18 64.4 3.6 1.7 1 0 0 1 1 1 1 Acetyl-coenzyme A synthetase N-terminus AMP-binding_C PF13193.6 CBZ27220.1 - 3.1e-18 66.5 0.2 6.3e-18 65.5 0.2 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain RRM_1 PF00076.22 CBZ27221.1 - 1.6e-11 43.8 0.0 2.6e-11 43.2 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF5559 PF17714.1 CBZ27221.1 - 0.16 11.8 8.8 0.48 10.3 8.8 1.8 1 0 0 1 1 1 0 Family of unknown function (DUF5559) TFIIA PF03153.13 CBZ27221.1 - 5.8 6.8 19.9 6.7 6.6 12.1 2.1 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit RRM_1 PF00076.22 CBZ27222.1 - 3.7e-13 49.1 0.0 6e-13 48.4 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) MMR_HSR1 PF01926.23 CBZ27223.1 - 8.9e-11 41.9 0.0 1.8e-10 40.9 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 CBZ27223.1 - 2.1e-05 24.7 0.3 9.1e-05 22.6 0.1 2.0 1 1 1 2 2 2 1 Dynamin family RsgA_GTPase PF03193.16 CBZ27223.1 - 6.2e-05 23.0 0.0 0.0028 17.6 0.0 2.3 2 0 0 2 2 2 1 RsgA GTPase AAA_29 PF13555.6 CBZ27223.1 - 0.0045 16.7 0.0 0.011 15.5 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain FeoB_N PF02421.18 CBZ27223.1 - 0.038 13.5 0.0 0.066 12.7 0.0 1.4 1 0 0 1 1 1 0 Ferrous iron transport protein B GTP_EFTU PF00009.27 CBZ27223.1 - 0.061 12.9 0.0 7.5 6.0 0.0 3.0 2 1 0 3 3 3 0 Elongation factor Tu GTP binding domain Parvo_NS1 PF01057.17 CBZ27223.1 - 0.08 12.0 0.0 0.14 11.2 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 ABC_tran PF00005.27 CBZ27223.1 - 0.11 13.0 0.0 0.31 11.6 0.0 1.7 1 0 0 1 1 1 0 ABC transporter DUF1738 PF08401.11 CBZ27224.1 - 0.029 14.5 0.0 0.3 11.2 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1738) DUF1738 PF08401.11 CBZ27225.1 - 0.00019 21.5 0.8 0.26 11.4 0.3 3.1 2 1 1 3 3 3 2 Domain of unknown function (DUF1738) DUF676 PF05057.14 CBZ27227.1 - 1.6e-12 47.4 0.0 4e-10 39.6 0.0 2.7 2 1 0 2 2 2 2 Putative serine esterase (DUF676) Corona_5a PF06336.11 CBZ27227.1 - 0.39 10.7 3.3 7.8 6.6 1.0 2.6 2 0 0 2 2 2 0 Coronavirus 5a protein SET PF00856.28 CBZ27228.1 - 6.8e-13 49.4 0.0 4.2e-10 40.3 0.0 3.1 3 0 0 3 3 3 1 SET domain zf-MYND PF01753.18 CBZ27228.1 - 0.00021 21.3 3.6 0.00021 21.3 3.6 3.3 4 1 0 4 4 4 1 MYND finger zf-Mss51 PF13824.6 CBZ27228.1 - 0.0025 17.9 1.9 0.0065 16.5 1.9 1.7 1 0 0 1 1 1 1 Zinc-finger of mitochondrial splicing suppressor 51 VATC PF18716.1 CBZ27228.1 - 0.84 9.5 6.3 0.55 10.1 2.2 2.7 2 0 0 2 2 2 0 Vms1-associating treble clef domain FAD-oxidase_C PF02913.19 CBZ27230.1 - 3.9e-48 164.3 0.1 6e-48 163.7 0.1 1.3 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 CBZ27230.1 - 8.2e-31 106.6 0.3 1.8e-30 105.5 0.3 1.6 1 0 0 1 1 1 1 FAD binding domain SET PF00856.28 CBZ27231.1 - 4.3e-08 33.7 0.0 6.9e-08 33.1 0.0 1.8 1 1 0 1 1 1 1 SET domain Na_H_Exchanger PF00999.21 CBZ27232.1 - 4.2e-49 167.3 43.3 6.2e-49 166.8 43.3 1.2 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Shisa PF13908.6 CBZ27233.1 - 0.016 15.4 0.4 0.016 15.4 0.4 1.6 2 0 0 2 2 2 0 Wnt and FGF inhibitory regulator DUF730 PF05325.11 CBZ27233.1 - 0.22 11.5 0.1 0.7 9.9 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF730) CO_deh_flav_C PF03450.17 CBZ27235.1 - 0.0052 16.9 1.8 2.5 8.3 0.2 3.1 2 0 0 2 2 2 2 CO dehydrogenase flavoprotein C-terminal domain TPR_14 PF13428.6 CBZ27235.1 - 0.0064 17.2 2.1 0.24 12.3 0.1 4.2 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.6 CBZ27235.1 - 0.015 15.5 4.7 0.97 9.8 0.0 3.8 3 1 0 3 3 3 0 Tetratricopeptide repeat Cornifin PF02389.15 CBZ27235.1 - 0.044 14.0 3.5 0.1 12.8 3.5 1.6 1 0 0 1 1 1 0 Cornifin (SPRR) family DUF4919 PF16266.5 CBZ27235.1 - 0.072 13.0 0.0 0.16 11.9 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4919) TPR_19 PF14559.6 CBZ27235.1 - 0.073 13.6 0.5 4 8.0 0.0 3.6 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_17 PF13431.6 CBZ27235.1 - 0.079 13.4 0.2 0.43 11.1 0.0 2.4 3 0 0 3 3 3 0 Tetratricopeptide repeat MSA-2c PF12238.8 CBZ27235.1 - 1.4 8.9 5.1 3.5 7.6 0.9 2.5 2 0 0 2 2 2 0 Merozoite surface antigen 2c ADH_zinc_N_2 PF13602.6 CBZ27236.1 - 1.7e-18 67.9 0.1 5.7e-18 66.3 0.0 1.8 2 1 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 CBZ27236.1 - 2.1e-07 31.0 0.0 1.9e-06 27.9 0.0 2.4 2 1 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 CBZ27236.1 - 2.7e-07 30.4 0.3 1.3e-06 28.2 0.1 2.2 2 1 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain RBM1CTR PF08081.11 CBZ27236.1 - 0.2 11.8 0.4 0.4 10.8 0.4 1.4 1 0 0 1 1 1 0 RBM1CTR (NUC064) family HupF_HypC PF01455.18 CBZ27236.1 - 0.31 11.2 2.0 27 5.0 0.0 3.3 2 1 1 3 3 3 0 HupF/HypC family Glyco_hydro_32N PF00251.20 CBZ27237.1 - 2.3e-91 306.6 1.1 2.6e-91 306.3 1.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 N-terminal domain Methyltransf_28 PF02636.17 CBZ27238.1 - 1.5e-60 205.1 0.0 2e-60 204.6 0.0 1.1 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase PgaPase_1 PF06162.12 CBZ27238.1 - 0.16 11.7 0.1 0.32 10.7 0.1 1.4 1 0 0 1 1 1 0 Putative pyroglutamyl peptidase PgaPase_1 NIF PF03031.18 CBZ27239.1 - 0.024 14.4 0.1 0.072 12.9 0.0 1.7 2 0 0 2 2 2 0 NLI interacting factor-like phosphatase Surp PF01805.20 CBZ27241.1 - 0.13 12.3 0.4 0.22 11.6 0.4 1.4 1 0 0 1 1 1 0 Surp module Peptidase_M17 PF00883.21 CBZ27242.1 - 1e-101 340.3 0.0 1.4e-101 339.9 0.0 1.2 1 0 0 1 1 1 1 Cytosol aminopeptidase family, catalytic domain Peptidase_M17_N PF02789.17 CBZ27242.1 - 0.1 12.5 0.7 0.58 10.0 0.2 2.6 2 1 0 2 2 2 0 Cytosol aminopeptidase family, N-terminal domain CHB_HEX_C_1 PF13290.6 CBZ27243.1 - 6e-06 26.2 0.2 0.0023 17.9 0.1 3.1 3 0 0 3 3 3 2 Chitobiase/beta-hexosaminidase C-terminal domain Fn3_assoc PF13287.6 CBZ27243.1 - 2.8e-05 24.2 0.0 0.33 11.1 0.0 3.6 3 0 0 3 3 3 2 Fn3 associated Adeno_E3_CR2 PF02439.15 CBZ27243.1 - 0.14 12.0 1.0 0.27 11.0 1.0 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Muted PF14942.6 CBZ27246.1 - 1.2 9.4 4.3 2.4 8.5 4.3 1.4 1 0 0 1 1 1 0 Organelle biogenesis, Muted-like protein OmpH PF03938.14 CBZ27247.1 - 0.038 14.3 2.2 0.1 12.9 0.7 1.9 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) FadA PF09403.10 CBZ27247.1 - 0.039 14.4 6.0 7.8 7.1 0.0 3.2 2 1 1 3 3 3 0 Adhesion protein FadA T3SSipB PF16535.5 CBZ27247.1 - 0.09 13.3 4.3 1.3 9.5 0.4 2.2 2 0 0 2 2 2 0 Type III cell invasion protein SipB YtxH PF12732.7 CBZ27251.1 - 8e-05 23.1 1.1 8.7e-05 23.0 1.1 1.0 1 0 0 1 1 1 1 YtxH-like protein LEA_4 PF02987.16 CBZ27251.1 - 0.00045 20.2 0.3 0.00064 19.7 0.3 1.4 1 1 0 1 1 1 1 Late embryogenesis abundant protein Apolipoprotein PF01442.18 CBZ27251.1 - 0.017 15.0 0.0 0.021 14.7 0.0 1.0 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain DUF883 PF05957.13 CBZ27251.1 - 0.043 14.4 0.2 0.055 14.1 0.2 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF883) TssO PF17561.2 CBZ27251.1 - 0.12 12.4 0.1 0.14 12.3 0.1 1.0 1 0 0 1 1 1 0 Type VI secretion system, TssO YtxH PF12732.7 CBZ27253.1 - 8e-05 23.1 1.1 8.7e-05 23.0 1.1 1.0 1 0 0 1 1 1 1 YtxH-like protein LEA_4 PF02987.16 CBZ27253.1 - 0.00045 20.2 0.3 0.00064 19.7 0.3 1.4 1 1 0 1 1 1 1 Late embryogenesis abundant protein Apolipoprotein PF01442.18 CBZ27253.1 - 0.017 15.0 0.0 0.021 14.7 0.0 1.0 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain DUF883 PF05957.13 CBZ27253.1 - 0.043 14.4 0.2 0.055 14.1 0.2 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF883) TssO PF17561.2 CBZ27253.1 - 0.12 12.4 0.1 0.14 12.3 0.1 1.0 1 0 0 1 1 1 0 Type VI secretion system, TssO KIAA1430 PF13879.6 CBZ27255.1 - 0.019 15.7 2.4 0.038 14.7 2.2 1.7 1 1 0 1 1 1 0 KIAA1430 homologue DUF11 PF01345.18 CBZ27256.1 - 0.011 16.0 0.0 0.88 9.9 0.0 3.4 3 1 0 3 3 3 0 Domain of unknown function DUF11 5-FTHF_cyc-lig PF01812.20 CBZ27257.1 - 2.3e-13 50.4 1.2 6.1e-10 39.3 0.0 3.3 3 1 0 3 3 3 2 5-formyltetrahydrofolate cyclo-ligase family Adeno_E1B_55K_N PF04623.12 CBZ27257.1 - 0.056 14.2 0.0 0.36 11.5 0.0 2.4 2 0 0 2 2 2 0 Adenovirus E1B protein N-terminus HIT PF01230.23 CBZ27258.1 - 1.1e-10 42.2 0.0 2.7e-10 40.9 0.0 1.7 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.8 CBZ27258.1 - 0.00016 22.2 0.1 0.001 19.5 0.1 2.2 1 1 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding HAD_SAK_1 PF10307.9 CBZ27259.1 - 0.00011 22.1 0.0 0.0011 18.8 0.0 2.0 2 0 0 2 2 2 1 HAD domain family 1 in Swiss Army Knife RNA repair proteins Bmt2 PF11968.8 CBZ27260.1 - 0.26 11.1 0.4 0.98 9.2 0.0 1.9 2 0 0 2 2 2 0 25S rRNA (adenine(2142)-N(1))-methyltransferase, Bmt2 LRR_4 PF12799.7 CBZ27261.1 - 1.4e-15 57.1 14.0 0.0017 18.7 0.1 7.2 4 3 4 8 8 8 6 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CBZ27261.1 - 0.00018 21.2 13.6 13 5.6 1.1 6.7 5 2 3 8 8 8 3 Leucine rich repeat LRR_5 PF13306.6 CBZ27261.1 - 0.0084 16.1 3.0 1.3 9.0 0.0 3.4 2 1 2 4 4 4 1 BspA type Leucine rich repeat region (6 copies) LRR_1 PF00560.33 CBZ27261.1 - 0.49 11.1 13.7 1.3e+02 3.8 0.0 7.1 7 3 0 7 7 7 0 Leucine Rich Repeat LRR_6 PF13516.6 CBZ27261.1 - 1.7 8.9 20.6 8.9 6.7 0.0 7.8 9 0 0 9 9 9 0 Leucine Rich repeat Stealth_CR2 PF11380.8 CBZ27262.1 - 2.3e-25 88.9 0.5 2.3e-20 72.8 0.0 2.8 3 0 0 3 3 3 2 Stealth protein CR2, conserved region 2 Stealth_CR3 PF17102.5 CBZ27262.1 - 1.2e-11 44.3 0.1 2.9e-11 43.1 0.1 1.7 1 0 0 1 1 1 1 Stealth protein CR3, conserved region 3 Stealth_CR2 PF11380.8 CBZ27263.1 - 1.3e-23 83.3 0.2 1e-18 67.5 0.0 2.4 2 0 0 2 2 2 2 Stealth protein CR2, conserved region 2 CH PF00307.31 CBZ27264.1 - 0.0011 19.1 0.0 0.0022 18.1 0.0 1.6 1 1 0 1 1 1 1 Calponin homology (CH) domain DHR10 PF18595.1 CBZ27265.1 - 7.4e-05 22.8 6.1 7.4e-05 22.8 6.1 5.2 4 1 0 4 4 4 1 Designed helical repeat protein 10 domain Cnn_1N PF07989.11 CBZ27265.1 - 0.00051 20.1 0.9 0.00051 20.1 0.9 4.5 4 1 1 5 5 5 1 Centrosomin N-terminal motif 1 HOOK PF05622.12 CBZ27265.1 - 0.00075 17.8 4.8 0.00075 17.8 4.8 3.6 4 0 0 4 4 4 1 HOOK protein Pox_A_type_inc PF04508.12 CBZ27265.1 - 0.0022 17.7 8.1 1.2 9.1 0.0 4.1 3 0 0 3 3 3 2 Viral A-type inclusion protein repeat DUF16 PF01519.16 CBZ27265.1 - 0.01 16.3 3.6 0.01 16.3 3.6 4.0 4 1 0 4 4 4 0 Protein of unknown function DUF16 APG6_N PF17675.1 CBZ27265.1 - 0.012 16.2 7.4 0.012 16.2 7.4 5.0 5 0 0 5 5 5 0 Apg6 coiled-coil region DUF3450 PF11932.8 CBZ27265.1 - 0.41 9.9 37.7 0.14 11.4 4.7 4.9 5 0 0 5 5 5 0 Protein of unknown function (DUF3450) Bacillus_HBL PF05791.11 CBZ27265.1 - 0.43 10.4 4.2 0.27 11.0 1.0 2.3 2 0 0 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) DUF4407 PF14362.6 CBZ27265.1 - 1.7 7.9 24.4 0.88 8.9 0.8 4.2 4 0 0 4 4 4 0 Domain of unknown function (DUF4407) DUF2681 PF10883.8 CBZ27265.1 - 2 8.9 5.4 12 6.4 0.8 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2681) PKcGMP_CC PF16808.5 CBZ27265.1 - 4.4 7.2 14.8 0.21 11.5 3.0 4.0 3 1 0 3 3 3 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Nbl1_Borealin_N PF10444.9 CBZ27266.1 - 0.096 12.3 0.1 0.096 12.3 0.1 4.7 5 0 0 5 5 5 0 Nbl1 / Borealin N terminal Prominin PF05478.11 CBZ27266.1 - 0.19 9.6 18.7 0.48 8.3 11.1 3.0 2 1 1 3 3 3 0 Prominin Shugoshin_N PF07558.11 CBZ27266.1 - 0.26 11.2 22.5 3 7.8 0.7 6.4 6 1 1 7 7 7 0 Shugoshin N-terminal coiled-coil region Pox_A_type_inc PF04508.12 CBZ27266.1 - 0.6 10.1 18.3 0.069 13.0 0.7 4.8 4 0 0 4 4 4 0 Viral A-type inclusion protein repeat HALZ PF02183.18 CBZ27266.1 - 1.1 9.5 24.0 1.3 9.3 0.3 6.6 6 1 1 7 7 7 0 Homeobox associated leucine zipper NPV_P10 PF05531.12 CBZ27266.1 - 7.4 7.1 18.3 15 6.2 0.3 5.1 5 0 0 5 5 5 0 Nucleopolyhedrovirus P10 protein BRCA-2_OB3 PF09104.10 CBZ27267.1 - 0.067 12.8 0.3 0.77 9.4 0.1 2.6 2 1 0 2 2 2 0 BRCA2, oligonucleotide/oligosaccharide-binding, domain 3 Serine_rich PF08824.10 CBZ27267.1 - 0.16 12.0 6.2 0.08 12.9 2.2 2.3 2 0 0 2 2 2 0 Serine rich protein interaction domain JIP_LZII PF16471.5 CBZ27267.1 - 0.36 11.0 0.1 0.36 11.0 0.1 3.5 4 1 0 4 4 4 0 JNK-interacting protein leucine zipper II CdiI_2 PF18593.1 CBZ27267.1 - 0.41 11.3 1.8 9.2 7.0 0.0 3.4 3 1 0 3 3 3 0 CdiI immunity protein DUF4061 PF13270.6 CBZ27267.1 - 1.9 8.9 8.8 0.61 10.4 0.6 3.2 2 1 1 3 3 3 0 Domain of unknown function (DUF4061) SKA2 PF16740.5 CBZ27267.1 - 2 8.2 18.3 0.15 11.8 2.0 3.8 4 0 0 4 4 4 0 Spindle and kinetochore-associated protein 2 WD40_4 PF16300.5 CBZ27269.1 - 2e-11 43.6 0.0 4.1e-11 42.6 0.0 1.5 1 0 0 1 1 1 1 Type of WD40 repeat DUF1899 PF08953.11 CBZ27269.1 - 5.1e-11 42.3 0.1 8.7e-11 41.5 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1899) WD40 PF00400.32 CBZ27269.1 - 1.3e-05 25.8 8.1 0.026 15.4 0.2 5.0 5 0 0 5 5 5 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBZ27269.1 - 0.00023 21.4 0.2 0.0044 17.3 0.1 2.5 1 1 1 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 CBZ27269.1 - 0.001 17.8 0.1 0.0016 17.2 0.1 1.3 1 0 0 1 1 1 1 Nucleoporin Nup120/160 ATG16 PF08614.11 CBZ27269.1 - 0.0062 16.8 2.2 0.0088 16.3 2.2 1.2 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) DUF4140 PF13600.6 CBZ27269.1 - 0.35 11.3 1.5 17 6.0 0.6 2.3 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) Ribosomal_S9 PF00380.19 CBZ27270.1 - 0.0003 21.3 0.0 0.00059 20.3 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein S9/S16 TMEM234 PF10639.9 CBZ27271.1 - 3.2e-15 56.2 2.2 8.6e-15 54.8 0.3 1.9 1 1 1 2 2 2 1 Putative transmembrane family 234 His_Phos_2 PF00328.22 CBZ27272.1 - 1.8e-10 40.8 0.4 4e-07 29.7 0.1 3.0 2 1 0 2 2 2 2 Histidine phosphatase superfamily (branch 2) Methyltransf_5 PF01795.19 CBZ27273.1 - 1.2e-30 107.1 0.0 1.7e-30 106.6 0.0 1.1 1 0 0 1 1 1 1 MraW methylase family Methyltransf_31 PF13847.6 CBZ27273.1 - 2.3e-05 24.3 0.0 0.0016 18.2 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 CBZ27273.1 - 0.00027 21.6 0.0 0.0025 18.5 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 CBZ27273.1 - 0.016 15.8 0.0 0.51 11.0 0.0 2.6 2 0 0 2 2 2 0 Methyltransferase domain MTS PF05175.14 CBZ27273.1 - 0.13 11.8 0.0 0.37 10.3 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase small domain SIR2 PF02146.17 CBZ27274.1 - 1.7e-35 122.5 0.2 3e-34 118.5 0.2 2.1 1 1 0 1 1 1 1 Sir2 family Ribosomal_L32p PF01783.23 CBZ27274.1 - 0.16 12.2 0.8 1.5 9.1 0.1 2.4 2 0 0 2 2 2 0 Ribosomal L32p protein family Cpn60_TCP1 PF00118.24 CBZ27275.1 - 1.4e-160 535.2 5.2 1.6e-160 535.0 5.2 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family V_ATPase_I PF01496.19 CBZ27275.1 - 0.19 9.6 0.0 0.24 9.3 0.0 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family PPR_1 PF12854.7 CBZ27277.1 - 1.6e-06 27.7 0.0 3.7e-06 26.5 0.0 1.7 2 0 0 2 2 2 1 PPR repeat PPR_3 PF13812.6 CBZ27277.1 - 3.5e-06 27.0 0.0 8.6e-06 25.7 0.0 1.7 1 0 0 1 1 1 1 Pentatricopeptide repeat domain PPR_2 PF13041.6 CBZ27277.1 - 9.1e-05 22.6 0.0 0.00046 20.3 0.0 2.2 2 0 0 2 2 2 1 PPR repeat family PPR PF01535.20 CBZ27277.1 - 0.0008 19.5 0.5 0.0027 17.8 0.1 2.2 2 0 0 2 2 2 1 PPR repeat C2-C2_1 PF11618.8 CBZ27278.1 - 1.1e-26 93.7 4.3 1.1e-26 93.6 0.2 3.0 2 1 1 3 3 3 1 First C2 domain of RPGR-interacting protein 1 UPF0242 PF06785.11 CBZ27278.1 - 4.8 7.2 37.0 0.036 14.2 10.3 3.5 2 1 0 3 3 3 0 Uncharacterised protein family (UPF0242) N-terminus NPV_P10 PF05531.12 CBZ27278.1 - 5.6 7.5 6.6 6.6 7.3 0.5 3.3 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein YabA PF06156.13 CBZ27278.1 - 6.8 7.4 28.4 1.2 9.8 0.2 4.7 2 1 2 4 4 4 0 Initiation control protein YabA RICTOR_M PF14666.6 CBZ27279.1 - 3.4e-22 78.2 0.0 1.6e-20 72.8 0.0 3.3 2 1 1 3 3 3 1 Rapamycin-insensitive companion of mTOR, middle domain RICTOR_N PF14664.6 CBZ27279.1 - 2.3e-15 56.5 1.0 1.1e-14 54.2 0.2 2.3 2 1 0 2 2 2 1 Rapamycin-insensitive companion of mTOR, N-term RasGEF_N_2 PF14663.6 CBZ27279.1 - 2.7e-12 47.0 1.4 7.4e-12 45.6 0.3 2.4 2 0 0 2 2 2 1 Rapamycin-insensitive companion of mTOR RasGEF_N domain RICTOR_V PF14668.6 CBZ27279.1 - 0.0013 18.9 0.3 0.13 12.5 0.0 4.0 3 0 0 3 3 3 1 Rapamycin-insensitive companion of mTOR, domain 5 RIX1 PF08167.12 CBZ27279.1 - 0.016 14.9 0.2 8.9 6.0 0.0 4.1 3 0 0 3 3 3 0 rRNA processing/ribosome biogenesis DUF2605 PF10792.9 CBZ27279.1 - 0.95 9.4 3.0 0.7 9.9 0.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2605) XPG_I PF00867.18 CBZ27282.1 - 8e-18 64.6 0.2 7e-16 58.4 0.1 2.8 2 0 0 2 2 2 1 XPG I-region XPG_N PF00752.17 CBZ27282.1 - 3.4e-14 53.1 0.0 3.2e-06 27.5 0.0 2.6 3 0 0 3 3 3 2 XPG N-terminal domain XPG_I_2 PF12813.7 CBZ27282.1 - 0.016 14.7 1.0 0.025 14.1 0.1 1.7 2 0 0 2 2 2 0 XPG domain containing DUF4908 PF16252.5 CBZ27282.1 - 0.58 9.7 5.0 0.77 9.3 0.4 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4908) Lentiviral_Tat PF02998.14 CBZ27283.1 - 0.12 12.4 0.0 0.34 11.0 0.0 1.7 1 0 0 1 1 1 0 Lentiviral Tat protein FA_hydroxylase PF04116.13 CBZ27285.1 - 2.1e-22 79.9 18.6 2.1e-22 79.9 18.6 2.2 2 1 1 3 3 3 1 Fatty acid hydroxylase superfamily DHC_N1 PF08385.12 CBZ27286.1 - 3.7e-152 507.9 0.0 3.7e-152 507.9 0.0 4.3 4 1 0 4 4 3 1 Dynein heavy chain, N-terminal region 1 AAA_6 PF12774.7 CBZ27286.1 - 1.4e-147 490.9 0.0 4.2e-147 489.4 0.0 1.9 1 0 0 1 1 1 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 CBZ27286.1 - 3.1e-114 382.2 8.7 3.1e-114 382.2 8.7 4.7 4 1 0 4 4 4 1 Dynein heavy chain, N-terminal region 2 AAA_8 PF12780.7 CBZ27286.1 - 1.5e-96 322.8 1.4 2.3e-96 322.1 0.0 2.2 2 0 0 2 2 2 1 P-loop containing dynein motor region D4 Dynein_C PF18199.1 CBZ27286.1 - 1.2e-85 287.5 0.4 4.8e-85 285.5 0.0 2.4 3 0 0 3 3 3 1 Dynein heavy chain C-terminal domain AAA_9 PF12781.7 CBZ27286.1 - 4.1e-79 264.8 0.6 4.1e-79 264.8 0.6 3.2 3 0 0 3 3 3 1 ATP-binding dynein motor region AAA_7 PF12775.7 CBZ27286.1 - 4.9e-63 211.9 0.6 4.8e-58 195.6 0.0 4.1 4 0 0 4 4 4 2 P-loop containing dynein motor region AAA_lid_11 PF18198.1 CBZ27286.1 - 4.9e-53 179.3 0.0 1.3e-52 177.9 0.0 1.8 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain Dynein_heavy PF03028.15 CBZ27286.1 - 3.3e-43 146.6 0.0 8.9e-42 141.9 0.0 3.5 4 0 0 4 4 4 1 Dynein heavy chain region D6 P-loop domain MT PF12777.7 CBZ27286.1 - 1.9e-41 142.3 15.8 3.9e-41 141.2 15.8 1.5 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_5 PF07728.14 CBZ27286.1 - 2.5e-24 85.9 0.0 4.2e-07 30.1 0.0 5.6 4 1 0 4 4 4 4 AAA domain (dynein-related subfamily) Dynein_AAA_lid PF17852.1 CBZ27286.1 - 6.4e-23 81.3 0.0 2.3e-22 79.5 0.0 2.1 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain AAA_lid_1 PF17857.1 CBZ27286.1 - 1.6e-16 60.3 2.0 2.4e-16 59.7 0.1 2.5 2 0 0 2 2 1 1 AAA+ lid domain AAA PF00004.29 CBZ27286.1 - 7.8e-06 26.3 0.0 0.45 10.9 0.0 4.0 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 CBZ27286.1 - 7.7e-05 23.1 8.4 0.76 10.1 0.0 6.4 6 0 0 6 6 5 1 AAA ATPase domain AAA_22 PF13401.6 CBZ27286.1 - 0.00052 20.3 8.5 0.83 9.9 0.0 6.4 6 0 0 6 6 6 1 AAA domain T2SSE PF00437.20 CBZ27286.1 - 0.00081 18.5 4.8 0.34 9.9 0.0 3.9 5 0 0 5 5 5 2 Type II/IV secretion system protein RNA_helicase PF00910.22 CBZ27286.1 - 0.021 15.2 0.1 8.5 6.8 0.0 3.4 3 0 0 3 3 3 0 RNA helicase AAA_18 PF13238.6 CBZ27286.1 - 0.034 14.7 1.0 4.9 7.7 0.0 4.5 4 0 0 4 4 4 0 AAA domain Sigma54_activat PF00158.26 CBZ27286.1 - 0.04 13.6 0.0 0.53 10.0 0.0 2.6 2 0 0 2 2 2 0 Sigma-54 interaction domain Mg_chelatase PF01078.21 CBZ27286.1 - 0.11 11.8 0.1 4 6.8 0.0 2.8 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI YceI PF04264.13 CBZ27287.1 - 0.0003 21.4 0.0 0.00035 21.2 0.0 1.2 1 0 0 1 1 1 1 YceI-like domain DNA_pol_B PF00136.21 CBZ27288.1 - 2e-82 277.4 0.0 2.5e-82 277.0 0.0 1.1 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.19 CBZ27288.1 - 0.00021 20.5 0.0 0.15 11.2 0.0 2.2 2 0 0 2 2 2 2 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.6 CBZ27288.1 - 0.00045 20.6 2.0 0.0013 19.2 0.2 2.6 3 0 0 3 3 3 1 C4-type zinc-finger of DNA polymerase delta Radical_SAM_C PF16199.5 CBZ27290.1 - 7.7e-17 61.1 0.2 1.5e-16 60.2 0.2 1.5 1 0 0 1 1 1 1 Radical_SAM C-terminal domain Radical_SAM PF04055.21 CBZ27290.1 - 3.2e-15 56.9 0.0 9.6e-15 55.3 0.0 1.9 1 0 0 1 1 1 1 Radical SAM superfamily Acetyltransf_1 PF00583.25 CBZ27290.1 - 7.7e-08 32.6 0.2 1.7e-07 31.5 0.2 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 CBZ27290.1 - 4.3e-05 23.5 0.2 0.00011 22.2 0.2 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Mito_carr PF00153.27 CBZ27292.1 - 3.4e-33 113.4 2.0 5.2e-15 55.2 0.1 3.5 3 1 0 3 3 3 3 Mitochondrial carrier protein RecC_C PF17946.1 CBZ27292.1 - 0.11 12.2 0.4 0.18 11.6 0.4 1.3 1 0 0 1 1 1 0 RecC C-terminal domain Ploopntkinase2 PF18747.1 CBZ27292.1 - 0.18 11.1 0.1 0.36 10.1 0.0 1.5 2 0 0 2 2 2 0 P-loop Nucleotide Kinase2 Helicase_C PF00271.31 CBZ27293.1 - 9.6e-12 45.2 0.0 3.4e-10 40.2 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 CBZ27293.1 - 3.6e-10 39.9 0.0 8.8e-10 38.6 0.0 1.6 1 1 0 1 1 1 1 DEAD/DEAH box helicase HHH_5 PF14520.6 CBZ27293.1 - 0.00077 20.0 0.1 0.017 15.7 0.0 2.5 2 0 0 2 2 2 1 Helix-hairpin-helix domain ResIII PF04851.15 CBZ27293.1 - 0.021 14.8 0.0 0.042 13.8 0.0 1.4 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit ThrE PF06738.12 CBZ27294.1 - 0.38 10.1 6.8 0.5 9.7 6.8 1.1 1 0 0 1 1 1 0 Putative threonine/serine exporter YjcB PF15940.5 CBZ27294.1 - 2.7 8.2 7.1 3 8.1 2.7 2.4 2 1 0 2 2 2 0 Family of unknown function Mog1 PF04603.12 CBZ27295.1 - 8e-34 117.0 0.0 1e-33 116.6 0.0 1.1 1 0 0 1 1 1 1 Ran-interacting Mog1 protein Fer2_3 PF13085.6 CBZ27297.1 - 1.6e-31 108.5 0.2 5.3e-31 106.8 0.1 1.8 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Fer2 PF00111.27 CBZ27297.1 - 0.004 17.1 0.7 0.013 15.4 0.7 1.8 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain TPR_21 PF09976.9 CBZ27297.1 - 0.019 14.7 1.3 0.035 13.8 1.3 1.4 1 0 0 1 1 1 0 Tetratricopeptide repeat-like domain Acetone_carb_G PF08882.11 CBZ27297.1 - 0.055 13.6 0.0 0.11 12.6 0.0 1.5 1 1 0 1 1 1 0 Acetone carboxylase gamma subunit TPR_14 PF13428.6 CBZ27297.1 - 0.16 12.9 1.2 0.36 11.8 0.2 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.6 CBZ27297.1 - 0.73 10.6 2.8 0.53 11.0 0.5 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_19 PF14559.6 CBZ27297.1 - 1 10.0 6.9 0.18 12.3 2.5 2.1 3 1 0 3 3 3 0 Tetratricopeptide repeat DHHC PF01529.20 CBZ27298.1 - 4.6e-30 104.5 16.5 4.6e-30 104.5 16.5 2.1 2 0 0 2 2 2 1 DHHC palmitoyltransferase DHHC PF01529.20 CBZ27299.1 - 1.2e-30 106.4 5.8 1.2e-30 106.4 5.8 2.2 2 0 0 2 2 2 1 DHHC palmitoyltransferase DUF3328 PF11807.8 CBZ27299.1 - 0.096 12.4 0.0 0.23 11.2 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3328) DHHC PF01529.20 CBZ27300.1 - 1.9e-23 83.1 13.8 1.9e-23 83.1 13.8 2.3 2 0 0 2 2 2 1 DHHC palmitoyltransferase PTPlike_phytase PF14566.6 CBZ27301.1 - 2.8e-119 394.6 0.3 3.1e-44 150.8 0.0 3.5 3 0 0 3 3 3 3 Inositol hexakisphosphate Y_phosphatase3 PF13350.6 CBZ27301.1 - 0.071 13.1 0.0 4.5 7.2 0.0 2.6 2 0 0 2 2 2 0 Tyrosine phosphatase family ADK PF00406.22 CBZ27302.1 - 9.8e-08 32.2 0.0 0.0058 16.8 0.0 2.3 2 0 0 2 2 2 2 Adenylate kinase AAA_17 PF13207.6 CBZ27302.1 - 1.3e-05 25.7 0.0 0.0092 16.4 0.0 2.6 2 1 0 3 3 3 2 AAA domain AAA_33 PF13671.6 CBZ27302.1 - 0.00036 20.7 0.1 0.0016 18.6 0.1 2.1 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.6 CBZ27302.1 - 0.0015 18.8 0.1 0.02 15.2 0.0 2.5 2 1 0 2 2 2 1 AAA domain AAA_28 PF13521.6 CBZ27302.1 - 0.0041 17.4 0.0 0.012 15.9 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA PF00004.29 CBZ27302.1 - 0.0049 17.3 0.1 0.024 15.1 0.0 2.1 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 CBZ27302.1 - 0.0082 16.5 1.9 0.034 14.5 0.7 2.8 1 1 0 1 1 1 1 AAA ATPase domain Rad17 PF03215.15 CBZ27302.1 - 0.019 14.9 1.0 0.23 11.3 0.0 2.2 2 0 0 2 2 2 0 Rad17 P-loop domain AAA_25 PF13481.6 CBZ27302.1 - 0.02 14.4 0.2 0.073 12.6 0.0 2.1 2 1 0 2 2 2 0 AAA domain AAA_18 PF13238.6 CBZ27302.1 - 0.025 15.1 0.0 0.2 12.2 0.0 2.1 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 CBZ27302.1 - 0.028 14.4 0.0 0.31 10.9 0.0 2.4 2 1 0 2 2 2 0 NACHT domain AAA_5 PF07728.14 CBZ27302.1 - 0.03 14.3 0.0 0.064 13.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Zeta_toxin PF06414.12 CBZ27302.1 - 0.044 13.1 0.4 0.36 10.1 0.1 2.3 2 0 0 2 2 2 0 Zeta toxin Mg_chelatase PF01078.21 CBZ27302.1 - 0.054 12.9 0.1 0.099 12.0 0.1 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.22 CBZ27302.1 - 0.12 12.8 0.0 0.21 12.0 0.0 1.5 1 0 0 1 1 1 0 RNA helicase KTI12 PF08433.10 CBZ27302.1 - 0.15 11.5 0.1 0.52 9.7 0.0 1.9 3 0 0 3 3 3 0 Chromatin associated protein KTI12 DAP3 PF10236.9 CBZ27302.1 - 0.18 10.9 0.1 0.43 9.7 0.0 1.6 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 DUF2277 PF10041.9 CBZ27302.1 - 0.26 11.6 5.2 10 6.5 0.2 3.4 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2277) B9-C2 PF07162.11 CBZ27304.1 - 3.3e-19 69.7 0.0 5.6e-19 69.0 0.0 1.4 1 0 0 1 1 1 1 Ciliary basal body-associated, B9 protein Peptidase_C27 PF05407.12 CBZ27305.1 - 0.025 14.7 5.2 0.037 14.1 5.2 1.2 1 0 0 1 1 1 0 Rubella virus endopeptidase Anoctamin PF04547.12 CBZ27306.1 - 0.11 11.4 0.1 0.11 11.3 0.1 1.1 1 0 0 1 1 1 0 Calcium-activated chloride channel Pet100 PF09803.9 CBZ27306.1 - 1.6 9.3 6.5 10 6.7 6.5 2.1 1 1 0 1 1 1 0 Pet100 zf-rbx1 PF12678.7 CBZ27307.1 - 4.9e-12 45.9 5.3 1e-11 44.9 5.3 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_2 PF13639.6 CBZ27307.1 - 2e-09 37.6 7.2 2.5e-08 34.1 4.9 2.3 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.6 CBZ27307.1 - 5.2e-07 29.4 9.7 9e-06 25.4 7.1 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CBZ27307.1 - 1e-06 28.5 5.0 2e-06 27.5 5.0 1.5 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CBZ27307.1 - 9.5e-06 25.5 3.6 2.6e-05 24.1 3.8 1.7 1 1 0 1 1 1 1 zinc-RING finger domain zf-ANAPC11 PF12861.7 CBZ27307.1 - 0.00029 20.8 4.9 0.0008 19.4 4.9 1.7 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.6 CBZ27307.1 - 0.00034 20.6 0.8 0.00034 20.6 0.8 2.3 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 CBZ27307.1 - 0.0043 16.9 7.5 0.011 15.6 3.4 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 CBZ27307.1 - 0.0049 16.6 0.9 0.0049 16.6 0.9 2.8 3 0 0 3 3 3 1 RING-like zinc finger Prok-RING_4 PF14447.6 CBZ27307.1 - 0.016 15.0 7.6 0.051 13.5 3.6 2.2 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 Zn_ribbon_17 PF17120.5 CBZ27307.1 - 0.033 13.8 2.0 0.033 13.8 2.0 2.0 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type zf-Nse PF11789.8 CBZ27307.1 - 0.29 11.0 4.4 0.25 11.2 2.7 1.7 2 0 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit RINGv PF12906.7 CBZ27307.1 - 0.3 11.2 6.1 0.12 12.5 3.2 1.8 2 0 0 2 2 2 0 RING-variant domain FANCL_C PF11793.8 CBZ27307.1 - 2 8.6 5.9 5.3 7.3 4.2 2.4 2 1 0 2 2 2 0 FANCL C-terminal domain V-SNARE PF05008.15 CBZ27308.1 - 2.1e-08 34.4 0.3 9.8e-06 25.9 0.0 3.2 2 1 1 3 3 3 1 Vesicle transport v-SNARE protein N-terminus Sec20 PF03908.13 CBZ27308.1 - 1e-05 25.3 1.4 2.3e-05 24.2 0.2 2.0 2 0 0 2 2 2 1 Sec20 V-SNARE_C PF12352.8 CBZ27308.1 - 0.0048 17.2 3.0 0.0048 17.2 3.0 2.6 3 0 0 3 3 3 1 Snare region anchored in the vesicle membrane C-terminus Laminin_I PF06008.14 CBZ27308.1 - 0.011 15.4 2.4 0.011 15.4 2.4 2.0 2 0 0 2 2 2 0 Laminin Domain I DUF5584 PF17822.1 CBZ27308.1 - 0.065 12.7 0.0 0.096 12.1 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5584) Med2 PF11214.8 CBZ27308.1 - 0.13 12.4 0.7 0.57 10.4 0.3 2.1 2 1 0 2 2 2 0 Mediator complex subunit 2 T2SSF PF00482.23 CBZ27308.1 - 0.17 11.9 0.7 0.35 10.8 0.2 1.7 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein F DUF1664 PF07889.12 CBZ27308.1 - 0.3 11.1 2.6 4.2 7.4 0.1 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) ZapB PF06005.12 CBZ27308.1 - 1.4 9.4 4.5 2.6 8.6 1.4 2.5 3 1 0 3 3 3 0 Cell division protein ZapB FliJ PF02050.16 CBZ27308.1 - 2.3 8.4 7.9 2.8 8.2 0.3 2.3 2 0 0 2 2 2 0 Flagellar FliJ protein V-SNARE PF05008.15 CBZ27309.1 - 6.2e-13 48.9 0.5 5.8e-12 45.8 0.0 2.8 2 2 2 4 4 4 1 Vesicle transport v-SNARE protein N-terminus V-SNARE_C PF12352.8 CBZ27309.1 - 2.8e-07 30.7 0.9 7.3e-07 29.4 0.9 1.7 1 0 0 1 1 1 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.13 CBZ27309.1 - 3.2e-05 23.8 3.9 3.4e-05 23.7 1.7 2.1 2 1 1 3 3 3 1 Sec20 Unstab_antitox PF09720.10 CBZ27309.1 - 0.00022 21.2 1.0 0.0006 19.8 0.2 2.3 2 1 0 2 2 2 1 Putative addiction module component KASH_CCD PF14662.6 CBZ27309.1 - 0.00032 20.6 4.4 0.15 11.9 1.0 2.2 2 0 0 2 2 2 2 Coiled-coil region of CCDC155 or KASH Baculo_F PF12259.8 CBZ27309.1 - 0.016 13.7 1.0 0.032 12.8 0.3 1.7 2 0 0 2 2 2 0 Baculovirus F protein DUF883 PF05957.13 CBZ27309.1 - 0.025 15.2 9.7 0.37 11.4 2.8 3.5 4 0 0 4 4 4 0 Bacterial protein of unknown function (DUF883) HR1 PF02185.16 CBZ27309.1 - 0.037 14.1 0.4 0.037 14.1 0.4 2.4 2 1 0 2 2 2 0 Hr1 repeat XTBD PF11952.8 CBZ27309.1 - 0.041 13.6 0.0 0.1 12.4 0.0 1.6 1 0 0 1 1 1 0 XRN-Two Binding Domain, XTBD DUF5082 PF16888.5 CBZ27309.1 - 0.042 14.1 0.3 0.042 14.1 0.3 2.9 4 0 0 4 4 2 0 Domain of unknown function (DUF5082) MCU PF04678.13 CBZ27309.1 - 0.043 13.9 1.0 0.6 10.2 0.1 2.2 2 0 0 2 2 2 0 Mitochondrial calcium uniporter Baculo_11_kDa PF06143.11 CBZ27309.1 - 0.043 13.4 0.7 0.083 12.5 0.7 1.4 1 0 0 1 1 1 0 Baculovirus 11 kDa family DUF2142 PF09913.9 CBZ27309.1 - 0.12 11.3 0.6 0.18 10.7 0.6 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2142) ODV-E18 PF10717.9 CBZ27309.1 - 0.13 12.1 1.1 0.25 11.2 1.1 1.4 1 0 0 1 1 1 0 Occlusion-derived virus envelope protein ODV-E18 DUF4969 PF16339.5 CBZ27309.1 - 0.13 12.6 0.2 0.3 11.5 0.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4969) Orf78 PF06024.12 CBZ27309.1 - 0.17 12.2 1.1 0.37 11.1 1.1 1.6 1 0 0 1 1 1 0 Orf78 (ac78) CLCA PF08434.11 CBZ27309.1 - 0.21 10.9 0.8 0.33 10.3 0.8 1.2 1 0 0 1 1 1 0 Calcium-activated chloride channel N terminal TRIQK PF15168.6 CBZ27309.1 - 0.27 11.2 1.4 0.44 10.5 0.3 1.9 2 0 0 2 2 2 0 Triple QxxK/R motif-containing protein family DUF1515 PF07439.11 CBZ27309.1 - 0.38 10.8 3.5 0.23 11.5 0.2 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1515) HXXSHH PF07586.11 CBZ27309.1 - 0.99 8.9 6.3 0.22 11.1 2.7 1.8 2 1 1 3 3 3 0 Protein of unknown function (DUF1552) OapA_N PF08525.11 CBZ27309.1 - 7.3 6.7 7.7 21 5.2 6.6 2.1 2 0 0 2 2 2 0 Opacity-associated protein A N-terminal motif XhlA PF10779.9 CBZ27309.1 - 8.3 6.7 6.8 4.2 7.7 0.2 2.5 2 1 1 3 3 3 0 Haemolysin XhlA RTT107_BRCT_5 PF16770.5 CBZ27310.1 - 0.13 12.1 0.0 0.31 10.9 0.0 1.6 1 0 0 1 1 1 0 Regulator of Ty1 transposition protein 107 BRCT domain EXOSC1 PF10447.9 CBZ27311.1 - 0.006 17.2 0.0 0.52 10.9 0.0 2.5 1 1 0 1 1 1 1 Exosome component EXOSC1/CSL4 TPH PF13868.6 CBZ27313.1 - 3.5e-35 121.2 126.3 3.5e-35 121.2 126.3 2.1 2 0 0 2 2 2 2 Trichohyalin-plectin-homology domain Semialdhyde_dh PF01118.24 CBZ27313.1 - 6.4 7.2 5.5 11 6.5 0.9 2.6 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain TIP41 PF04176.13 CBZ27314.1 - 3.8e-22 78.6 0.0 6.3e-22 77.9 0.0 1.3 1 0 0 1 1 1 1 TIP41-like family GAF_2 PF13185.6 CBZ27314.1 - 2.3e-09 37.7 0.0 4.2e-09 36.8 0.0 1.4 1 0 0 1 1 1 1 GAF domain GAF PF01590.26 CBZ27314.1 - 3.6e-06 27.7 0.0 8.9e-06 26.4 0.0 1.7 1 0 0 1 1 1 1 GAF domain LRR_4 PF12799.7 CBZ27315.1 - 7.3e-06 26.2 4.4 0.0013 19.1 0.0 2.9 2 1 1 3 3 3 2 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 CBZ27315.1 - 0.01 15.4 0.1 0.019 14.4 0.1 1.4 1 1 0 1 1 1 0 Leucine-rich repeat CDC45 PF02724.14 CBZ27315.1 - 0.21 9.8 8.7 0.27 9.5 8.7 1.1 1 0 0 1 1 1 0 CDC45-like protein LRR_6 PF13516.6 CBZ27315.1 - 0.31 11.2 2.9 5.6 7.3 0.0 3.4 4 0 0 4 4 4 0 Leucine Rich repeat Ala_racemase_N PF01168.20 CBZ27316.1 - 1.3e-20 74.0 0.0 1.6e-20 73.7 0.0 1.0 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain LRR_8 PF13855.6 CBZ27317.1 - 6e-10 38.7 10.3 0.19 11.5 0.3 5.1 4 2 0 4 4 4 4 Leucine rich repeat LRR_4 PF12799.7 CBZ27317.1 - 2.6e-08 34.0 12.8 0.025 15.0 0.8 5.7 4 1 2 6 6 6 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 CBZ27317.1 - 3.2e-06 26.9 6.0 4.5 8.2 0.1 6.3 7 1 0 7 7 7 1 Leucine Rich Repeat LRR_6 PF13516.6 CBZ27317.1 - 0.012 15.6 14.8 0.89 9.8 0.5 5.2 6 0 0 6 6 6 0 Leucine Rich repeat PMP1_2 PF08114.11 CBZ27317.1 - 0.028 14.2 0.1 0.055 13.2 0.1 1.4 1 0 0 1 1 1 0 ATPase proteolipid family STD1 PF17235.2 CBZ27317.1 - 0.088 12.4 0.0 0.14 11.8 0.0 1.3 1 0 0 1 1 1 0 STD1/MTH1 Co_AT_N PF12557.8 CBZ27317.1 - 0.13 12.2 0.6 0.25 11.3 0.6 1.5 1 0 0 1 1 1 0 Cob(I)alamin adenosyltransferase N terminal V_ATPase_I PF01496.19 CBZ27319.1 - 3.1e-263 875.5 20.1 1.3e-178 595.6 0.2 3.0 1 1 2 3 3 3 3 V-type ATPase 116kDa subunit family DUF3021 PF11457.8 CBZ27319.1 - 0.0018 18.6 3.3 0.0018 18.6 3.3 3.3 3 1 0 3 3 3 1 Protein of unknown function (DUF3021) BCDHK_Adom3 PF10436.9 CBZ27319.1 - 0.029 14.2 0.2 0.058 13.2 0.2 1.4 1 0 0 1 1 1 0 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase Atg14 PF10186.9 CBZ27319.1 - 0.55 9.3 2.7 4.9 6.1 2.7 2.1 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 CLZ PF16526.5 CBZ27319.1 - 1.6 9.1 4.2 1.8 9.0 0.2 2.8 3 0 0 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels DegS PF05384.11 CBZ27319.1 - 4.4 6.8 9.2 6.6 6.2 0.6 3.1 2 1 1 3 3 3 0 Sensor protein DegS SKA2 PF16740.5 CBZ27319.1 - 7.4 6.4 7.5 1 9.1 0.2 2.7 3 0 0 3 3 3 0 Spindle and kinetochore-associated protein 2 UbiA PF01040.18 CBZ27320.1 - 1.8e-48 165.0 22.3 2.6e-48 164.5 22.3 1.3 1 0 0 1 1 1 1 UbiA prenyltransferase family NFRKB_winged PF14465.6 CBZ27322.1 - 0.13 12.5 0.0 0.29 11.3 0.0 1.5 1 0 0 1 1 1 0 NFRKB Winged Helix-like NRDE-2 PF08424.10 CBZ27323.1 - 2.1e-06 27.1 2.9 0.012 14.7 0.1 4.2 3 1 1 4 4 4 3 NRDE-2, necessary for RNA interference TPR_14 PF13428.6 CBZ27323.1 - 0.12 13.2 22.7 22 6.2 0.0 9.1 7 2 2 9 9 9 0 Tetratricopeptide repeat Beach PF02138.18 CBZ27325.1 - 7.4e-88 294.5 0.0 9.6e-88 294.1 0.0 1.1 1 0 0 1 1 1 1 Beige/BEACH domain Nuc_deoxyrib_tr PF05014.15 CBZ27326.1 - 1.3e-36 125.5 0.0 1.5e-36 125.3 0.0 1.1 1 0 0 1 1 1 1 Nucleoside 2-deoxyribosyltransferase Nuc_deoxyri_tr3 PF11071.8 CBZ27326.1 - 0.13 12.3 0.0 0.2 11.7 0.0 1.3 1 1 0 1 1 1 0 Nucleoside 2-deoxyribosyltransferase YtoQ Nuc_deoxyri_tr2 PF15891.5 CBZ27326.1 - 0.2 12.0 0.0 0.33 11.3 0.0 1.5 1 1 0 1 1 1 0 Nucleoside 2-deoxyribosyltransferase like BCDHK_Adom3 PF10436.9 CBZ27327.1 - 6.4e-24 84.6 0.0 1.4e-23 83.5 0.0 1.5 1 1 1 2 2 2 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.26 CBZ27327.1 - 0.09 13.3 0.0 0.19 12.3 0.0 1.5 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase IL11 PF07400.11 CBZ27327.1 - 0.13 11.9 0.0 5.8 6.5 0.0 2.2 2 0 0 2 2 2 0 Interleukin 11 ANTH PF07651.16 CBZ27328.1 - 1.3e-25 90.0 0.4 2e-25 89.4 0.4 1.3 1 1 0 1 1 1 1 ANTH domain ENTH PF01417.20 CBZ27328.1 - 0.035 14.1 0.0 0.069 13.2 0.0 1.4 1 0 0 1 1 1 0 ENTH domain Ribosomal_L22 PF00237.19 CBZ27330.1 - 4.6e-32 110.3 0.4 5.6e-32 110.0 0.4 1.1 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e DUF4616 PF15394.6 CBZ27331.1 - 0.028 13.4 0.0 0.052 12.5 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4616) zf-RING_2 PF13639.6 CBZ27334.1 - 9.8e-08 32.2 5.3 9.8e-08 32.2 5.3 4.8 4 2 2 6 6 6 1 Ring finger domain zf-RING_11 PF17123.5 CBZ27334.1 - 9.5e-07 28.5 4.2 4.7e-06 26.3 4.2 2.3 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_UBOX PF13445.6 CBZ27334.1 - 9.9e-06 25.5 2.2 9.9e-06 25.5 2.2 3.6 4 0 0 4 4 4 1 RING-type zinc-finger zf-C3HC4 PF00097.25 CBZ27334.1 - 3.7e-05 23.5 2.1 3.7e-05 23.5 2.1 3.9 3 1 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 CBZ27334.1 - 0.00018 21.3 2.6 0.00018 21.3 2.6 3.9 5 0 0 5 5 5 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 CBZ27334.1 - 0.0016 18.7 3.6 0.0016 18.7 3.6 3.6 2 1 0 2 2 2 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 CBZ27334.1 - 0.0035 17.3 4.3 0.0035 17.3 4.3 4.7 4 2 1 5 5 5 1 zinc-RING finger domain DUF3592 PF12158.8 CBZ27335.1 - 3.9e-08 33.5 0.4 5.7e-08 32.9 0.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3592) Enkurin PF13864.6 CBZ27336.1 - 1.1e-18 67.5 4.3 1.6e-18 67.0 4.3 1.3 1 0 0 1 1 1 1 Calmodulin-binding YkyA PF10368.9 CBZ27336.1 - 0.11 12.2 2.6 0.09 12.4 1.0 1.6 1 1 0 1 1 1 0 Putative cell-wall binding lipoprotein PARP_regulatory PF01358.18 CBZ27337.1 - 1.3e-12 47.3 0.0 2e-12 46.7 0.0 1.3 1 0 0 1 1 1 1 Poly A polymerase regulatory subunit UPF0182 PF03699.13 CBZ27337.1 - 0.13 10.4 0.0 0.18 9.9 0.0 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0182) WD40 PF00400.32 CBZ27338.1 - 0.055 14.3 9.6 10 7.2 0.1 4.3 4 0 0 4 4 4 0 WD domain, G-beta repeat Blt1_C PF17183.4 CBZ27338.1 - 0.058 13.0 0.0 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 Get5 carboxyl domain SsgA PF04686.12 CBZ27338.1 - 0.087 12.8 0.0 0.21 11.6 0.0 1.6 1 0 0 1 1 1 0 Streptomyces sporulation and cell division protein, SsgA Ank_2 PF12796.7 CBZ27339.1 - 5.5e-40 135.8 12.1 3.9e-13 49.8 0.3 4.3 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CBZ27339.1 - 6.1e-33 112.8 5.3 3.3e-08 33.9 0.0 5.5 2 2 4 6 6 6 6 Ankyrin repeats (many copies) Ank_5 PF13857.6 CBZ27339.1 - 4.2e-28 97.0 4.2 8.8e-09 35.5 0.1 4.6 2 1 3 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 CBZ27339.1 - 2.3e-24 82.8 3.4 0.0011 19.3 0.0 7.2 7 0 0 7 7 7 5 Ankyrin repeat Ank PF00023.30 CBZ27339.1 - 2.1e-22 78.5 2.9 7.4e-05 23.0 0.0 7.2 7 0 0 7 7 7 5 Ankyrin repeat TPR_1 PF00515.28 CBZ27339.1 - 3.1e-09 36.2 2.5 0.0096 15.7 0.0 3.9 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 CBZ27339.1 - 2.5e-06 27.2 5.9 0.13 12.4 0.0 4.0 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_17 PF13431.6 CBZ27339.1 - 0.00027 21.1 2.6 0.59 10.6 0.1 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 CBZ27339.1 - 0.00053 19.6 1.0 0.24 11.1 0.1 3.0 3 0 0 3 3 3 2 TPR repeat ANAPC3 PF12895.7 CBZ27339.1 - 0.029 14.6 1.3 0.077 13.2 1.3 1.7 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 PEX11 PF05648.14 CBZ27340.1 - 1.4e-10 41.0 1.3 6.8e-06 25.7 0.0 2.1 1 1 1 2 2 2 2 Peroxisomal biogenesis factor 11 (PEX11) Phosducin PF02114.16 CBZ27342.1 - 1.1e-06 27.8 0.0 1.4e-06 27.5 0.0 1.2 1 0 0 1 1 1 1 Phosducin MRC1 PF09444.10 CBZ27342.1 - 0.0028 18.2 0.3 0.0047 17.5 0.3 1.3 1 0 0 1 1 1 1 MRC1-like domain EF-1_beta_acid PF10587.9 CBZ27342.1 - 3.5 8.1 7.1 1.4 9.5 3.3 2.4 2 0 0 2 2 2 0 Eukaryotic elongation factor 1 beta central acidic region AAA PF00004.29 CBZ27343.1 - 1e-29 103.6 0.0 4.8e-27 95.0 0.0 2.5 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 CBZ27343.1 - 8.4e-09 35.8 0.0 0.0089 16.3 0.0 2.7 2 1 0 2 2 2 2 AAA domain NACHT PF05729.12 CBZ27343.1 - 2.1e-08 34.2 0.2 0.012 15.6 0.3 3.5 2 2 1 3 3 3 2 NACHT domain AAA_16 PF13191.6 CBZ27343.1 - 2.5e-07 31.2 10.2 0.00018 21.9 0.2 4.2 2 2 0 3 3 3 1 AAA ATPase domain RNA_helicase PF00910.22 CBZ27343.1 - 3.7e-05 24.1 0.0 0.027 14.8 0.0 2.5 2 0 0 2 2 2 1 RNA helicase AAA_5 PF07728.14 CBZ27343.1 - 4.8e-05 23.4 0.1 0.0041 17.1 0.0 2.7 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) ABC_tran PF00005.27 CBZ27343.1 - 0.00018 22.0 0.3 0.058 13.9 0.0 2.3 2 0 0 2 2 2 1 ABC transporter AAA_7 PF12775.7 CBZ27343.1 - 0.00025 20.6 0.1 0.9 9.0 0.0 2.5 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA_33 PF13671.6 CBZ27343.1 - 0.00026 21.2 0.1 0.074 13.2 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 CBZ27343.1 - 0.00033 20.3 1.2 0.85 9.4 0.1 2.4 2 0 0 2 2 2 2 P-loop containing region of AAA domain TIP49 PF06068.13 CBZ27343.1 - 0.001 18.4 0.1 0.0044 16.3 0.0 1.8 2 0 0 2 2 2 1 TIP49 P-loop domain RsgA_GTPase PF03193.16 CBZ27343.1 - 0.0013 18.7 0.3 0.21 11.5 0.0 2.3 2 0 0 2 2 2 1 RsgA GTPase NB-ARC PF00931.22 CBZ27343.1 - 0.0014 17.9 0.0 0.034 13.3 0.0 2.2 2 0 0 2 2 2 1 NB-ARC domain AAA_28 PF13521.6 CBZ27343.1 - 0.0016 18.7 0.3 0.92 9.7 0.0 2.6 2 1 0 2 2 2 1 AAA domain AAA_30 PF13604.6 CBZ27343.1 - 0.0029 17.4 0.2 0.12 12.0 0.1 2.4 2 0 0 2 2 2 1 AAA domain Sigma54_activat PF00158.26 CBZ27343.1 - 0.0045 16.7 0.0 0.15 11.7 0.0 2.2 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_24 PF13479.6 CBZ27343.1 - 0.0054 16.5 0.2 1.9 8.2 0.0 2.4 2 1 0 2 2 2 1 AAA domain AAA_25 PF13481.6 CBZ27343.1 - 0.0056 16.3 0.1 0.67 9.5 0.0 2.6 2 0 0 2 2 2 1 AAA domain DUF815 PF05673.13 CBZ27343.1 - 0.0075 15.4 0.1 0.42 9.7 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF815) ATPase_2 PF01637.18 CBZ27343.1 - 0.012 15.5 0.0 0.51 10.2 0.0 2.4 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea Viral_helicase1 PF01443.18 CBZ27343.1 - 0.012 15.3 0.1 3.4 7.4 0.0 2.8 3 0 0 3 3 3 0 Viral (Superfamily 1) RNA helicase Rad17 PF03215.15 CBZ27343.1 - 0.017 15.0 0.3 0.46 10.4 0.1 2.3 2 0 0 2 2 2 0 Rad17 P-loop domain FtsK_SpoIIIE PF01580.18 CBZ27343.1 - 0.019 14.4 0.3 0.019 14.4 0.3 1.9 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_14 PF13173.6 CBZ27343.1 - 0.021 14.9 0.0 3.5 7.7 0.0 2.3 2 0 0 2 2 2 0 AAA domain TsaE PF02367.17 CBZ27343.1 - 0.033 14.2 0.3 2.5 8.1 0.0 2.2 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE TniB PF05621.11 CBZ27343.1 - 0.052 12.9 0.0 11 5.3 0.0 2.3 2 0 0 2 2 2 0 Bacterial TniB protein AAA_18 PF13238.6 CBZ27343.1 - 0.075 13.6 0.0 1.7 9.2 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.6 CBZ27343.1 - 0.091 13.1 0.0 0.93 9.8 0.0 2.2 2 0 0 2 2 2 0 AAA domain Mg_chelatase PF01078.21 CBZ27343.1 - 0.098 12.0 0.1 0.47 9.8 0.0 2.0 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_23 PF13476.6 CBZ27343.1 - 0.11 13.0 0.2 6.6 7.2 0.0 2.1 2 0 0 2 2 2 0 AAA domain NTP_transf_3 PF12804.7 CBZ27343.1 - 0.11 12.8 2.5 0.23 11.8 1.4 2.1 2 1 0 2 2 2 0 MobA-like NTP transferase domain Cytidylate_kin PF02224.18 CBZ27343.1 - 0.11 12.2 0.0 0.21 11.3 0.0 1.4 1 0 0 1 1 1 0 Cytidylate kinase PRK PF00485.18 CBZ27343.1 - 0.12 12.1 0.1 2.5 7.8 0.0 2.2 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family AAA_27 PF13514.6 CBZ27343.1 - 0.12 11.9 0.0 0.63 9.6 0.0 2.0 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 CBZ27343.1 - 0.15 11.8 0.0 0.6 9.8 0.0 1.9 2 0 0 2 2 2 0 IstB-like ATP binding protein Roc PF08477.13 CBZ27343.1 - 0.17 12.1 0.0 19 5.5 0.0 2.5 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_17 PF13207.6 CBZ27343.1 - 0.19 12.1 0.3 31 5.0 0.0 2.4 2 0 0 2 2 2 0 AAA domain HEAT PF02985.22 CBZ27344.1 - 3.3e-09 36.2 17.9 0.22 11.9 0.1 8.1 7 0 0 7 7 7 5 HEAT repeat HEAT_2 PF13646.6 CBZ27344.1 - 3.1e-07 30.7 11.9 0.0016 18.8 0.1 4.9 4 2 1 5 5 5 3 HEAT repeats Cnd1 PF12717.7 CBZ27344.1 - 8.4e-05 22.7 0.0 1.3 9.0 0.0 3.9 3 2 1 4 4 4 2 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.20 CBZ27344.1 - 0.00034 19.3 0.2 0.13 10.8 0.0 3.4 1 1 3 4 4 4 2 Adaptin N terminal region Vac14_Fab1_bd PF12755.7 CBZ27344.1 - 0.0013 19.3 0.2 4 8.1 0.1 3.6 4 0 0 4 4 4 2 Vacuolar 14 Fab1-binding region TFIIS_M PF07500.14 CBZ27345.1 - 2.8e-06 27.8 0.1 4.1e-06 27.2 0.1 1.3 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS), central domain Zn_Tnp_IS1595 PF12760.7 CBZ27345.1 - 0.022 14.7 2.5 0.075 13.0 2.5 2.0 1 0 0 1 1 1 0 Transposase zinc-ribbon domain TFIIS_C PF01096.18 CBZ27345.1 - 0.4 10.6 5.9 0.34 10.8 0.8 2.2 2 0 0 2 2 2 0 Transcription factor S-II (TFIIS) TFIIS_M PF07500.14 CBZ27346.1 - 1.2e-15 58.0 0.3 2e-15 57.2 0.3 1.4 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS), central domain TFIIS_C PF01096.18 CBZ27346.1 - 7.4e-15 54.5 4.5 1.4e-14 53.7 4.5 1.5 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS) Baculo_LEF5_C PF11792.8 CBZ27346.1 - 2e-05 24.2 0.9 6.5e-05 22.5 0.9 1.9 1 1 0 1 1 1 1 Baculoviridae late expression factor 5 C-terminal domain zf-DNL PF05180.12 CBZ27346.1 - 0.0057 16.6 0.4 0.013 15.4 0.4 1.6 1 0 0 1 1 1 1 DNL zinc finger Elf1 PF05129.13 CBZ27346.1 - 0.084 12.9 1.2 0.17 12.0 1.2 1.4 1 0 0 1 1 1 0 Transcription elongation factor Elf1 like ubiquitin PF00240.23 CBZ27347.1 - 0.012 15.3 0.0 0.023 14.5 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin family Pkinase PF00069.25 CBZ27348.1 - 4.7e-52 177.0 0.0 3.2e-51 174.2 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ27348.1 - 1.3e-24 86.9 0.0 3.2e-19 69.3 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase FHA PF00498.26 CBZ27348.1 - 1.2e-14 54.4 0.1 3.2e-14 53.0 0.1 1.8 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 CBZ27348.1 - 6.5e-09 36.0 0.0 1.8e-08 34.6 0.0 1.7 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain APH PF01636.23 CBZ27348.1 - 0.00047 20.1 0.2 0.85 9.5 0.0 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family CAF1C_H4-bd PF12265.8 CBZ27349.1 - 3.9e-11 43.1 0.1 1.2e-10 41.5 0.1 1.9 1 0 0 1 1 1 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex ANAPC4_WD40 PF12894.7 CBZ27349.1 - 0.0013 18.9 1.9 0.35 11.2 0.2 3.6 2 1 0 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 CBZ27349.1 - 0.028 15.3 0.6 0.028 15.3 0.6 4.7 5 0 0 5 5 5 0 WD domain, G-beta repeat DEAD PF00270.29 CBZ27350.1 - 2e-33 115.6 0.5 6e-33 114.1 0.5 1.9 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CBZ27350.1 - 1.6e-15 57.4 0.0 6.6e-15 55.4 0.0 2.1 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 CBZ27350.1 - 3.9e-07 30.2 0.0 1.4e-06 28.4 0.0 1.9 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit SNF2_N PF00176.23 CBZ27350.1 - 0.00015 20.6 0.8 0.0011 17.7 0.0 2.1 2 0 0 2 2 2 1 SNF2 family N-terminal domain Metallophos PF00149.28 CBZ27352.1 - 7.2e-08 33.2 0.0 1.4e-06 28.9 0.0 2.2 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase WD40 PF00400.32 CBZ27353.1 - 3.5e-07 30.8 3.7 0.04 14.8 0.1 4.0 3 0 0 3 3 3 2 WD domain, G-beta repeat tify PF06200.14 CBZ27353.1 - 0.0032 16.8 2.6 1.7 8.0 0.1 2.7 2 0 0 2 2 2 2 tify domain NIF PF03031.18 CBZ27354.1 - 9.8e-33 113.1 0.4 1.3e-32 112.7 0.4 1.1 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Hydrolase PF00702.26 CBZ27354.1 - 0.096 13.0 0.0 1.2 9.4 0.0 2.0 1 1 1 2 2 2 0 haloacid dehalogenase-like hydrolase zf-RING_2 PF13639.6 CBZ27355.1 - 0.00047 20.4 9.1 0.00047 20.4 9.1 2.4 3 0 0 3 3 3 1 Ring finger domain zf-C3HC4 PF00097.25 CBZ27355.1 - 0.04 13.8 7.1 0.13 12.2 7.1 2.0 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 CBZ27355.1 - 0.053 13.8 8.7 0.18 12.1 8.6 2.1 1 1 0 1 1 1 0 RING-H2 zinc finger domain Ribonuc_P_40 PF08584.11 CBZ27355.1 - 0.23 10.7 1.9 0.6 9.3 0.0 2.4 2 0 0 2 2 2 0 Ribonuclease P 40kDa (Rpp40) subunit RINGv PF12906.7 CBZ27355.1 - 1.3 9.2 6.5 3.5 7.8 6.5 1.8 1 0 0 1 1 1 0 RING-variant domain zf-ANAPC11 PF12861.7 CBZ27355.1 - 4.4 7.4 11.2 0.3 11.2 4.5 2.6 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 11 RING-H2 finger FANCL_C PF11793.8 CBZ27355.1 - 9.4 6.5 11.6 0.34 11.1 4.3 2.3 2 0 0 2 2 2 0 FANCL C-terminal domain Fumerase_C PF05683.12 CBZ27357.1 - 4.5e-86 287.4 0.0 7.4e-86 286.7 0.0 1.4 1 0 0 1 1 1 1 Fumarase C-terminus Fumerase PF05681.14 CBZ27357.1 - 6e-80 268.5 0.0 7.7e-80 268.2 0.0 1.1 1 0 0 1 1 1 1 Fumarate hydratase (Fumerase) Rsm22 PF09243.10 CBZ27358.1 - 9.4e-29 100.5 0.7 3.9e-16 59.1 0.1 3.0 3 0 0 3 3 3 2 Mitochondrial small ribosomal subunit Rsm22 Phosphodiest PF01663.22 CBZ27359.1 - 3.9e-09 36.6 0.0 8e-09 35.5 0.0 1.5 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Metalloenzyme PF01676.18 CBZ27359.1 - 0.0099 15.3 0.1 0.016 14.6 0.1 1.2 1 0 0 1 1 1 1 Metalloenzyme superfamily DUF3179 PF11376.8 CBZ27359.1 - 0.12 11.8 0.0 0.24 10.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3179) Phage_holin_3_7 PF05449.11 CBZ27360.1 - 0.045 13.8 2.6 0.11 12.5 2.6 1.6 1 0 0 1 1 1 0 Putative 3TM holin, Phage_holin_3 Nuc_sug_transp PF04142.15 CBZ27361.1 - 4.5e-55 187.0 9.5 7.3e-54 183.1 7.1 2.2 2 1 0 2 2 2 2 Nucleotide-sugar transporter CrtC PF07143.11 CBZ27361.1 - 0.17 12.5 0.1 0.96 10.1 0.0 2.0 2 0 0 2 2 2 0 CrtC N-terminal lipocalin domain Trp_oprn_chp PF09534.10 CBZ27361.1 - 0.22 11.3 5.3 0.11 12.2 1.2 2.6 2 0 0 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) EamA PF00892.20 CBZ27361.1 - 3.6 7.8 31.3 0.17 12.0 4.5 3.1 3 1 0 3 3 3 0 EamA-like transporter family Nuc_sug_transp PF04142.15 CBZ27362.1 - 4.5e-54 183.7 12.0 4.3e-53 180.5 7.9 2.3 2 1 0 2 2 2 2 Nucleotide-sugar transporter UAA PF08449.11 CBZ27362.1 - 0.041 13.1 9.2 0.057 12.6 9.2 1.3 1 0 0 1 1 1 0 UAA transporter family EamA PF00892.20 CBZ27362.1 - 1.5 9.0 28.0 0.043 14.0 2.4 2.8 3 1 0 3 3 3 0 EamA-like transporter family Trp_oprn_chp PF09534.10 CBZ27362.1 - 2.7 7.7 8.5 0.098 12.5 1.1 2.4 2 1 0 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) Aminotran_1_2 PF00155.21 CBZ27363.1 - 3.4e-70 237.0 0.0 3.9e-70 236.8 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II DUF1192 PF06698.11 CBZ27364.1 - 0.97 9.5 8.7 9.9 6.3 0.2 4.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1192) RF-1 PF00472.20 CBZ27365.1 - 0.033 14.1 0.0 0.064 13.2 0.0 1.4 1 0 0 1 1 1 0 RF-1 domain NAD_binding_9 PF13454.6 CBZ27366.1 - 0.16 11.9 0.2 0.4 10.7 0.2 1.6 1 0 0 1 1 1 0 FAD-NAD(P)-binding AAA_16 PF13191.6 CBZ27367.1 - 0.045 14.1 0.0 0.09 13.2 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain Peptidase_C12 PF01088.21 CBZ27368.1 - 1e-56 192.0 0.0 1.4e-56 191.5 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 UCH_C PF18031.1 CBZ27368.1 - 1.9e-12 46.8 0.5 3.7e-12 46.0 0.5 1.5 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolases Stealth_CR2 PF11380.8 CBZ27370.1 - 6.1e-11 42.5 0.0 5.2e-09 36.3 0.0 2.4 2 0 0 2 2 2 2 Stealth protein CR2, conserved region 2 Stealth_CR3 PF17102.5 CBZ27370.1 - 0.0075 16.2 0.5 0.025 14.5 0.5 2.0 1 0 0 1 1 1 1 Stealth protein CR3, conserved region 3 Stealth_CR2 PF11380.8 CBZ27371.1 - 6.1e-11 42.4 0.0 5.2e-09 36.3 0.0 2.4 2 0 0 2 2 2 2 Stealth protein CR2, conserved region 2 Stealth_CR3 PF17102.5 CBZ27371.1 - 0.0071 16.2 0.5 0.025 14.5 0.5 2.1 1 0 0 1 1 1 1 Stealth protein CR3, conserved region 3 ThiF PF00899.21 CBZ27372.1 - 4e-32 111.5 0.1 4.5e-32 111.3 0.1 1.2 1 0 0 1 1 1 1 ThiF family Shikimate_DH PF01488.20 CBZ27372.1 - 0.013 15.6 0.3 0.027 14.6 0.3 1.5 1 1 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Response_reg PF00072.24 CBZ27372.1 - 0.02 15.0 0.1 0.035 14.3 0.1 1.4 1 0 0 1 1 1 0 Response regulator receiver domain NAD_binding_7 PF13241.6 CBZ27372.1 - 0.024 15.1 0.3 0.061 13.8 0.3 1.8 1 0 0 1 1 1 0 Putative NAD(P)-binding GTP-bdg_N PF13167.6 CBZ27372.1 - 0.054 14.2 0.1 0.13 13.0 0.1 1.6 1 0 0 1 1 1 0 GTP-binding GTPase N-terminal F420_oxidored PF03807.17 CBZ27372.1 - 0.073 13.7 0.2 0.32 11.6 0.1 2.0 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent Sacchrp_dh_NADP PF03435.18 CBZ27372.1 - 0.077 13.3 6.0 0.41 10.9 4.7 2.7 2 1 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain ThiS-like PF14453.6 CBZ27372.1 - 0.088 12.9 0.0 0.21 11.7 0.0 1.5 1 0 0 1 1 1 0 ThiS-like ubiquitin MCPVI PF02993.14 CBZ27373.1 - 0.38 10.5 0.0 0.38 10.5 0.0 2.4 3 0 0 3 3 3 0 Minor capsid protein VI Kelch_4 PF13418.6 CBZ27374.1 - 3.6e-29 100.5 5.6 3.5e-08 33.3 0.0 7.0 6 2 0 6 6 6 4 Galactose oxidase, central domain Kelch_5 PF13854.6 CBZ27374.1 - 1.1e-21 76.3 0.7 5.9e-09 35.7 0.0 5.9 6 0 0 6 6 6 3 Kelch motif Kelch_6 PF13964.6 CBZ27374.1 - 3.1e-17 62.2 0.1 0.0001 22.4 0.1 6.1 4 1 1 5 5 5 4 Kelch motif Kelch_2 PF07646.15 CBZ27374.1 - 6e-09 35.5 0.8 0.0016 18.3 0.0 5.0 5 0 0 5 5 5 2 Kelch motif Kelch_3 PF13415.6 CBZ27374.1 - 1.9e-07 31.2 22.5 0.0018 18.5 0.1 9.1 9 2 0 9 9 9 2 Galactose oxidase, central domain Kelch_1 PF01344.25 CBZ27374.1 - 1e-06 28.2 6.5 0.0028 17.2 0.0 5.8 7 0 0 7 7 7 2 Kelch motif zf-CGNR PF11706.8 CBZ27374.1 - 0.61 10.0 10.9 0.21 11.4 0.2 3.8 3 0 0 3 3 3 0 CGNR zinc finger PQQ_3 PF13570.6 CBZ27374.1 - 7.9 7.1 8.5 7.6 7.2 1.0 4.6 5 0 0 5 5 5 0 PQQ-like domain LRR_4 PF12799.7 CBZ27375.1 - 4.2e-49 163.7 61.2 2.2e-06 27.9 0.0 14.2 10 3 6 16 16 16 16 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CBZ27375.1 - 1.5e-44 149.5 65.2 4.3e-10 39.2 1.8 11.0 7 4 3 10 10 10 10 Leucine rich repeat LRR_9 PF14580.6 CBZ27375.1 - 2.4e-37 128.1 23.6 2.2e-09 37.1 0.1 8.3 5 4 3 8 8 8 7 Leucine-rich repeat LRR_6 PF13516.6 CBZ27375.1 - 7.8e-10 38.0 35.8 1.4 9.2 0.0 15.8 16 1 1 17 17 17 4 Leucine Rich repeat Dicer_dimer PF03368.14 CBZ27376.1 - 0.21 11.8 0.1 0.43 10.8 0.1 1.4 1 0 0 1 1 1 0 Dicer dimerisation domain Spectrin PF00435.21 CBZ27377.1 - 0.0024 18.4 8.9 0.0024 18.4 8.9 5.5 4 2 1 6 6 6 1 Spectrin repeat Spc7 PF08317.11 CBZ27377.1 - 0.091 11.6 35.8 0.22 10.3 3.7 3.3 3 0 0 3 3 3 0 Spc7 kinetochore protein Cbl_N PF02262.16 CBZ27377.1 - 0.13 12.3 2.3 15 5.6 1.3 2.7 2 0 0 2 2 2 0 CBL proto-oncogene N-terminal domain 1 DUF1664 PF07889.12 CBZ27377.1 - 0.66 10.0 12.3 0.15 12.1 1.1 3.4 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) ADIP PF11559.8 CBZ27377.1 - 6.1 6.9 41.4 0.81 9.8 16.6 4.1 4 0 0 4 4 4 0 Afadin- and alpha -actinin-Binding DnaJ PF00226.31 CBZ27378.1 - 1.7e-16 60.1 1.7 3.2e-16 59.2 1.7 1.5 1 0 0 1 1 1 1 DnaJ domain TFIID-31kDa PF02291.15 CBZ27378.1 - 0.0019 18.2 0.0 0.0044 17.1 0.0 1.6 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit tRNA-synt_His PF13393.6 CBZ27378.1 - 0.023 14.0 0.2 0.054 12.8 0.2 1.5 1 0 0 1 1 1 0 Histidyl-tRNA synthetase Metal_resist PF13801.6 CBZ27378.1 - 1.3 9.2 8.8 0.17 12.0 0.2 3.2 3 0 0 3 3 3 0 Heavy-metal resistance ENT PF03735.14 CBZ27379.1 - 0.0006 19.8 0.1 0.0032 17.5 0.0 2.0 2 0 0 2 2 2 1 ENT domain TRM13 PF05206.14 CBZ27380.1 - 4.8e-13 49.2 0.2 5.9e-06 26.0 0.1 2.2 2 0 0 2 2 2 2 Methyltransferase TRM13 Methyltransf_32 PF13679.6 CBZ27380.1 - 3.2e-05 24.0 2.9 0.0002 21.4 1.0 2.7 1 1 1 2 2 2 1 Methyltransferase domain TRM13 PF05206.14 CBZ27381.1 - 2.3e-17 63.4 0.0 5.8e-17 62.1 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase TRM13 Methyltransf_32 PF13679.6 CBZ27381.1 - 7.3e-05 22.8 2.0 0.00046 20.2 2.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain WBP-1 PF11669.8 CBZ27382.1 - 0.00028 21.5 0.1 0.00039 21.0 0.1 1.3 1 0 0 1 1 1 1 WW domain-binding protein 1 LapA_dom PF06305.11 CBZ27382.1 - 0.0033 17.2 0.1 0.0044 16.8 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide assembly protein A domain CMV_US PF08001.11 CBZ27382.1 - 0.095 12.0 0.0 0.1 11.8 0.0 1.1 1 0 0 1 1 1 0 CMV US Protocadherin PF08374.11 CBZ27383.1 - 0.0032 17.5 0.0 0.0032 17.5 0.0 1.1 1 0 0 1 1 1 1 Protocadherin EphA2_TM PF14575.6 CBZ27383.1 - 0.067 14.1 0.0 0.073 14.0 0.0 1.1 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Npa1 PF11707.8 CBZ27386.1 - 6.2e-08 32.4 0.0 1.6e-07 31.1 0.0 1.7 1 0 0 1 1 1 1 Ribosome 60S biogenesis N-terminal NopRA1 PF16201.5 CBZ27386.1 - 1.3e-07 31.5 0.0 5.7e-07 29.3 0.0 2.3 1 1 0 1 1 1 1 Nucleolar pre-ribosomal-associated protein 1 MOR2-PAG1_N PF14222.6 CBZ27386.1 - 0.024 13.6 0.1 0.045 12.7 0.1 1.3 1 0 0 1 1 1 0 Cell morphogenesis N-terminal Arm PF00514.23 CBZ27386.1 - 0.12 12.4 0.8 1.4 9.1 0.5 3.2 2 0 0 2 2 2 0 Armadillo/beta-catenin-like repeat SNF2_N PF00176.23 CBZ27387.1 - 1.4e-31 109.5 0.0 2.2e-31 108.8 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 CBZ27387.1 - 6.2e-10 39.4 0.0 2.8e-09 37.3 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 CBZ27387.1 - 2.8e-07 30.7 0.0 5e-07 29.9 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Flavi_DEAD PF07652.14 CBZ27387.1 - 0.016 15.2 0.3 0.18 11.8 0.1 2.6 2 0 0 2 2 2 0 Flavivirus DEAD domain TniB PF05621.11 CBZ27387.1 - 0.056 12.8 0.2 0.29 10.5 0.0 2.0 2 0 0 2 2 2 0 Bacterial TniB protein UCH PF00443.29 CBZ27388.1 - 2.2e-46 158.5 0.0 3.2e-46 157.9 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 CBZ27388.1 - 1e-09 38.4 0.9 3.4e-05 23.6 0.0 2.5 3 0 0 3 3 3 2 Ubiquitin carboxyl-terminal hydrolase ATP-synt_C PF00137.21 CBZ27389.1 - 1.8e-07 31.4 14.2 1.8e-07 31.4 14.2 1.6 2 0 0 2 2 2 1 ATP synthase subunit C Kinesin PF00225.23 CBZ27390.1 - 1.6e-90 303.5 0.0 2e-90 303.1 0.0 1.1 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 CBZ27390.1 - 3.8e-17 62.6 0.0 8e-17 61.6 0.0 1.6 1 0 0 1 1 1 1 Microtubule binding Peptidase_C97 PF05903.14 CBZ27391.1 - 5.2e-29 101.0 0.0 9.7e-29 100.1 0.0 1.4 1 0 0 1 1 1 1 PPPDE putative peptidase domain LRAT PF04970.13 CBZ27391.1 - 0.013 15.8 0.0 0.032 14.5 0.0 1.6 1 0 0 1 1 1 0 Lecithin retinol acyltransferase Pkinase PF00069.25 CBZ27393.1 - 2e-34 119.2 0.0 3.2e-17 62.8 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ27393.1 - 1.1e-10 41.2 0.0 1.6e-05 24.3 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Sugar_tr PF00083.24 CBZ27394.1 - 1.3e-128 429.7 34.6 1.5e-128 429.5 34.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CBZ27394.1 - 8.7e-29 100.5 39.3 8.7e-29 100.5 39.3 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF523 PF04463.12 CBZ27397.1 - 2.1e-14 53.8 0.0 5.5e-12 45.9 0.0 2.5 1 1 0 1 1 1 1 Protein of unknown function (DUF523) zf-Tim10_DDP PF02953.15 CBZ27398.1 - 0.00026 20.6 3.1 0.00036 20.1 3.1 1.3 1 1 0 1 1 1 1 Tim10/DDP family zinc finger SRP54 PF00448.22 CBZ27399.1 - 3e-74 248.9 1.1 5.5e-74 248.0 1.1 1.5 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain SRP_SPB PF02978.19 CBZ27399.1 - 4.4e-25 88.2 1.6 4.4e-25 88.2 1.6 4.2 4 1 0 4 4 4 1 Signal peptide binding domain SRP54_N PF02881.19 CBZ27399.1 - 2.7e-13 49.9 3.4 3e-13 49.8 1.4 2.2 2 0 0 2 2 1 1 SRP54-type protein, helical bundle domain cobW PF02492.19 CBZ27399.1 - 4e-07 29.8 0.4 1.5e-06 27.9 0.4 2.0 1 1 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.6 CBZ27399.1 - 3.5e-05 24.0 0.0 7.4e-05 22.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.6 CBZ27399.1 - 6.9e-05 23.3 1.3 0.00011 22.7 0.2 2.0 2 0 0 2 2 1 1 AAA domain AAA_30 PF13604.6 CBZ27399.1 - 0.00069 19.4 0.2 0.0021 17.8 0.2 1.9 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 CBZ27399.1 - 0.0013 18.1 0.1 0.0026 17.1 0.1 1.4 1 0 0 1 1 1 1 Zeta toxin MeaB PF03308.16 CBZ27399.1 - 0.0015 17.6 0.0 0.0059 15.6 0.0 1.9 1 1 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_22 PF13401.6 CBZ27399.1 - 0.0039 17.5 0.3 0.032 14.5 0.0 2.6 3 0 0 3 3 2 1 AAA domain Methyltransf_24 PF13578.6 CBZ27399.1 - 0.0057 17.7 0.0 0.064 14.3 0.0 2.3 1 1 1 2 2 2 1 Methyltransferase domain SRPRB PF09439.10 CBZ27399.1 - 0.006 16.0 0.4 3.3 7.1 0.1 2.5 2 0 0 2 2 2 2 Signal recognition particle receptor beta subunit CLP1_P PF16575.5 CBZ27399.1 - 0.0067 16.2 0.3 0.52 10.1 0.1 2.4 1 1 1 2 2 2 1 mRNA cleavage and polyadenylation factor CLP1 P-loop Fe-ADH PF00465.19 CBZ27399.1 - 0.011 14.6 0.0 0.02 13.7 0.0 1.5 1 0 0 1 1 1 0 Iron-containing alcohol dehydrogenase AAA_24 PF13479.6 CBZ27399.1 - 0.013 15.2 0.4 0.072 12.8 0.1 2.2 2 0 0 2 2 2 0 AAA domain APS_kinase PF01583.20 CBZ27399.1 - 0.014 15.3 0.0 0.034 14.1 0.0 1.6 1 0 0 1 1 1 0 Adenylylsulphate kinase ATP_bind_1 PF03029.17 CBZ27399.1 - 0.015 15.1 0.1 0.1 12.4 0.0 2.2 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein CbiA PF01656.23 CBZ27399.1 - 0.017 15.2 0.0 0.062 13.4 0.0 1.9 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_16 PF13191.6 CBZ27399.1 - 0.017 15.5 0.0 0.038 14.4 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain GhoS PF11080.8 CBZ27399.1 - 0.02 14.9 0.1 15 5.7 0.1 3.3 4 0 0 4 4 2 0 Endoribonuclease GhoS ResIII PF04851.15 CBZ27399.1 - 0.024 14.7 0.5 2.8 7.9 0.0 2.3 1 1 1 2 2 2 0 Type III restriction enzyme, res subunit NTPase_1 PF03266.15 CBZ27399.1 - 0.027 14.4 2.0 3.1 7.7 2.0 2.5 1 1 0 1 1 1 0 NTPase MobB PF03205.14 CBZ27399.1 - 0.05 13.5 0.0 0.18 11.7 0.0 2.0 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B SWI2_SNF2 PF18766.1 CBZ27399.1 - 0.055 13.1 0.8 1.3 8.6 0.0 2.3 1 1 1 2 2 2 0 SWI2/SNF2 ATPase Dynamin_N PF00350.23 CBZ27399.1 - 0.065 13.3 1.1 0.11 12.6 0.0 1.8 2 0 0 2 2 2 0 Dynamin family AAA_19 PF13245.6 CBZ27399.1 - 0.094 13.1 0.3 0.25 11.7 0.0 1.9 2 0 0 2 2 1 0 AAA domain AAA_31 PF13614.6 CBZ27399.1 - 0.1 12.5 1.2 4.3 7.2 0.0 2.6 2 1 1 3 3 2 0 AAA domain DUF2209 PF09974.9 CBZ27399.1 - 0.17 12.2 1.7 0.53 10.6 0.3 2.4 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2209) MMR_HSR1 PF01926.23 CBZ27399.1 - 0.18 11.9 1.6 1.1 9.4 0.9 2.7 2 1 0 2 2 1 0 50S ribosome-binding GTPase HAD_SAK_2 PF18143.1 CBZ27401.1 - 1.1e-30 106.8 0.0 2.2e-30 105.8 0.0 1.5 1 0 0 1 1 1 1 HAD domain in Swiss Army Knife RNA repair proteins Gp-FAR-1 PF05823.12 CBZ27401.1 - 0.00046 20.6 0.8 0.00085 19.7 0.7 1.5 1 1 0 1 1 1 1 Nematode fatty acid retinoid binding protein (Gp-FAR-1) CENP-F_leu_zip PF10473.9 CBZ27401.1 - 0.0016 18.4 3.0 0.0016 18.4 3.0 1.8 2 0 0 2 2 2 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 PV-1 PF06637.11 CBZ27401.1 - 0.0028 16.6 1.6 0.0046 15.9 1.6 1.4 1 0 0 1 1 1 1 PV-1 protein (PLVAP) CENP-H PF05837.12 CBZ27401.1 - 0.17 12.3 6.9 0.06 13.8 4.0 1.7 1 1 0 1 1 1 0 Centromere protein H (CENP-H) TolA_bind_tri PF16331.5 CBZ27401.1 - 0.24 11.5 4.9 0.17 12.0 2.4 2.0 2 0 0 2 2 2 0 TolA binding protein trimerisation APG6_N PF17675.1 CBZ27401.1 - 0.24 11.9 7.9 0.13 12.8 5.5 1.7 1 1 0 1 1 1 0 Apg6 coiled-coil region DivIC PF04977.15 CBZ27401.1 - 0.67 9.8 5.2 0.25 11.1 2.4 1.7 2 0 0 2 2 2 0 Septum formation initiator ZapB PF06005.12 CBZ27401.1 - 0.81 10.2 7.5 0.95 9.9 6.2 1.8 1 1 1 2 2 2 0 Cell division protein ZapB Spc24 PF08286.11 CBZ27401.1 - 1.2 9.4 4.1 2.1 8.7 4.1 1.5 1 1 0 1 1 1 0 Spc24 subunit of Ndc80 DUF1043 PF06295.12 CBZ27401.1 - 2.2 8.3 5.2 0.49 10.4 1.7 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1043) SNF2_N PF00176.23 CBZ27402.1 - 4.4e-57 193.4 0.0 7.9e-57 192.5 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 CBZ27402.1 - 6.5e-17 61.9 0.0 2.6e-16 59.9 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 CBZ27402.1 - 8.9e-10 38.8 0.0 2.1e-09 37.6 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 CBZ27402.1 - 2.4e-08 33.9 0.0 5.6e-08 32.8 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase ERCC3_RAD25_C PF16203.5 CBZ27402.1 - 2.7e-06 26.8 0.1 6.9e-06 25.4 0.0 1.7 2 0 0 2 2 2 1 ERCC3/RAD25/XPB C-terminal helicase TEX13 PF15186.6 CBZ27402.1 - 0.29 10.8 2.2 0.73 9.5 2.2 1.7 1 0 0 1 1 1 0 Testis-expressed sequence 13 protein family DUF3886 PF13025.6 CBZ27402.1 - 2.1 8.6 5.7 0.28 11.4 0.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3886) Malic_M PF03949.15 CBZ27403.1 - 2.8e-83 279.1 0.3 3.7e-83 278.7 0.3 1.1 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.19 CBZ27403.1 - 1.3e-66 223.9 0.0 4.1e-66 222.3 0.0 1.8 2 0 0 2 2 2 1 Malic enzyme, N-terminal domain Malic_M PF03949.15 CBZ27404.1 - 1.7e-82 276.6 0.1 5.3e-82 275.0 0.1 1.7 2 0 0 2 2 2 1 Malic enzyme, NAD binding domain malic PF00390.19 CBZ27404.1 - 2.8e-69 232.6 0.0 4.7e-69 231.8 0.0 1.3 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain tRNA_edit PF04073.15 CBZ27404.1 - 0.093 12.8 0.2 0.16 12.0 0.2 1.4 1 0 0 1 1 1 0 Aminoacyl-tRNA editing domain Nop10p PF04135.12 CBZ27405.1 - 0.14 12.2 0.2 0.14 12.2 0.2 2.2 3 0 0 3 3 3 0 Nucleolar RNA-binding protein, Nop10p family KN17_SH3 PF18131.1 CBZ27406.1 - 0.22 11.7 0.4 0.44 10.7 0.4 1.4 1 0 0 1 1 1 0 KN17 SH3-like C-terminal domain PTS_2-RNA PF01885.16 CBZ27408.1 - 6e-55 186.1 0.0 8.5e-55 185.6 0.0 1.2 1 0 0 1 1 1 1 RNA 2'-phosphotransferase, Tpt1 / KptA family RNase_T PF00929.24 CBZ27408.1 - 1.1e-20 74.8 0.0 1.7e-20 74.2 0.0 1.3 1 0 0 1 1 1 1 Exonuclease Syja_N PF02383.18 CBZ27409.1 - 3.1e-55 187.7 0.0 4.7e-55 187.2 0.0 1.2 1 0 0 1 1 1 1 SacI homology domain DUF547 PF04784.14 CBZ27409.1 - 8.6e-05 22.6 0.0 0.00019 21.5 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF547 Ax_dynein_light PF10211.9 CBZ27411.1 - 3.5e-78 261.9 4.9 4e-78 261.7 4.9 1.0 1 0 0 1 1 1 1 Axonemal dynein light chain Filament PF00038.21 CBZ27411.1 - 0.00017 21.3 9.0 0.0014 18.3 3.4 2.1 1 1 1 2 2 2 2 Intermediate filament protein Jnk-SapK_ap_N PF09744.9 CBZ27411.1 - 0.00019 21.7 8.4 0.001 19.3 4.8 2.1 2 0 0 2 2 2 1 JNK_SAPK-associated protein-1 APG6_N PF17675.1 CBZ27411.1 - 0.00078 20.0 8.5 0.00078 20.0 8.5 1.7 2 0 0 2 2 2 1 Apg6 coiled-coil region Mei5 PF10376.9 CBZ27411.1 - 0.012 15.5 1.7 0.016 15.1 1.7 1.3 1 0 0 1 1 1 0 Double-strand recombination repair protein bZIP_1 PF00170.21 CBZ27411.1 - 0.019 15.0 2.2 0.019 15.0 2.2 2.1 2 0 0 2 2 2 0 bZIP transcription factor CENP-H PF05837.12 CBZ27411.1 - 0.051 14.0 6.2 0.11 12.9 6.2 1.5 1 0 0 1 1 1 0 Centromere protein H (CENP-H) HALZ PF02183.18 CBZ27411.1 - 0.072 13.3 2.9 0.27 11.5 0.8 2.8 3 0 0 3 3 3 0 Homeobox associated leucine zipper End3 PF12761.7 CBZ27411.1 - 0.16 12.2 5.8 0.07 13.3 3.4 1.6 2 0 0 2 2 2 0 Actin cytoskeleton-regulatory complex protein END3 Syntaxin-6_N PF09177.11 CBZ27411.1 - 0.2 12.2 4.1 0.37 11.4 4.1 1.5 1 0 0 1 1 1 0 Syntaxin 6, N-terminal Spc24 PF08286.11 CBZ27411.1 - 0.23 11.7 5.3 0.28 11.4 4.3 1.6 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 FadA PF09403.10 CBZ27411.1 - 0.27 11.7 6.5 0.68 10.4 6.5 1.7 1 0 0 1 1 1 0 Adhesion protein FadA ERM PF00769.19 CBZ27411.1 - 2.1 8.1 16.0 0.06 13.2 10.0 1.5 2 0 0 2 2 2 0 Ezrin/radixin/moesin family DivIC PF04977.15 CBZ27411.1 - 4.7 7.0 10.0 0.65 9.8 4.0 2.4 2 1 1 3 3 3 0 Septum formation initiator DHR10 PF18595.1 CBZ27411.1 - 7.8 6.6 18.8 1.1 9.4 14.6 1.6 2 0 0 2 2 2 0 Designed helical repeat protein 10 domain TIM PF00121.18 CBZ27412.1 - 1.9e-89 299.2 0.5 2.1e-89 299.1 0.5 1.0 1 0 0 1 1 1 1 Triosephosphate isomerase EMP24_GP25L PF01105.24 CBZ27414.1 - 1.2e-12 48.2 0.0 1.4e-12 47.9 0.0 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD DUF779 PF05610.11 CBZ27414.1 - 0.029 14.6 0.0 7.3 6.9 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF779) DUF5564 PF17719.1 CBZ27414.1 - 0.13 12.4 0.0 0.22 11.7 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5564) DNA_pol_A PF00476.20 CBZ27416.1 - 6.5e-52 176.8 0.1 2e-51 175.2 0.1 1.8 1 1 0 1 1 1 1 DNA polymerase family A P4Ha_N PF08336.11 CBZ27416.1 - 0.042 13.9 0.0 0.094 12.7 0.0 1.5 1 0 0 1 1 1 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region DUF3100 PF11299.8 CBZ27417.1 - 4.3 6.7 8.7 2.1 7.7 2.4 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3100) MCM PF00493.23 CBZ27418.1 - 4.4e-88 294.2 0.0 6.5e-88 293.6 0.0 1.2 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 CBZ27418.1 - 7.5e-34 116.3 0.4 1.7e-33 115.1 0.4 1.6 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 CBZ27418.1 - 3.2e-23 81.9 1.6 2.1e-22 79.3 1.6 2.4 1 1 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 CBZ27418.1 - 3.5e-09 37.2 0.0 9.1e-09 35.8 0.0 1.6 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 CBZ27418.1 - 1.5e-07 31.0 0.0 3.7e-06 26.5 0.0 2.6 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 CBZ27418.1 - 0.00024 21.0 0.0 0.00064 19.6 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 CBZ27418.1 - 0.00042 20.3 0.0 0.001 19.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) PUA PF01472.20 CBZ27418.1 - 0.0044 17.0 1.8 0.66 10.0 0.2 2.6 2 0 0 2 2 2 2 PUA domain Sigma54_activat PF00158.26 CBZ27418.1 - 0.036 13.8 0.0 0.1 12.3 0.0 1.7 1 0 0 1 1 1 0 Sigma-54 interaction domain UBA PF00627.31 CBZ27418.1 - 0.17 11.8 0.1 0.55 10.2 0.1 1.9 1 0 0 1 1 1 0 UBA/TS-N domain Methyltransf_25 PF13649.6 CBZ27419.1 - 0.0037 17.9 0.1 0.03 15.0 0.0 2.5 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.14 CBZ27419.1 - 0.0045 16.5 0.0 0.01 15.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_31 PF13847.6 CBZ27419.1 - 0.18 11.6 0.0 0.33 10.8 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain ANAPC4_WD40 PF12894.7 CBZ27420.1 - 0.057 13.7 0.0 0.14 12.4 0.0 1.8 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 4 WD40 domain DGF-1_C PF11040.8 CBZ27420.1 - 4 7.5 6.5 1.5 8.8 1.3 2.6 2 0 0 2 2 2 0 Dispersed gene family protein 1 of Trypanosoma cruzi C-terminus RabGAP-TBC PF00566.18 CBZ27422.1 - 2.2e-10 40.5 2.1 8.7e-10 38.6 2.2 1.8 2 0 0 2 2 2 1 Rab-GTPase-TBC domain UCR_Fe-S_N PF10399.9 CBZ27422.1 - 2.2 7.7 4.2 3.4 7.1 0.3 2.4 2 0 0 2 2 2 0 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal Phage_TAC_1 PF06222.11 CBZ27424.1 - 0.074 12.8 0.0 0.17 11.7 0.0 1.6 1 0 0 1 1 1 0 Phage tail assembly chaperone DUF1290 PF06947.12 CBZ27424.1 - 0.24 11.5 0.8 0.54 10.4 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1290) RFC1 PF08519.12 CBZ27426.1 - 2.3e-42 144.8 0.0 6.5e-42 143.3 0.0 1.8 2 0 0 2 2 2 1 Replication factor RFC1 C terminal domain AAA PF00004.29 CBZ27426.1 - 9.8e-12 45.4 0.0 2.5e-11 44.1 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 CBZ27426.1 - 5.1e-08 33.1 0.0 1.1e-07 32.0 0.0 1.5 1 0 0 1 1 1 1 Rad17 P-loop domain Zeta_toxin PF06414.12 CBZ27426.1 - 0.00045 19.6 0.9 0.0018 17.6 0.0 2.2 2 0 0 2 2 2 1 Zeta toxin RuvB_N PF05496.12 CBZ27426.1 - 0.00088 19.1 0.0 0.0017 18.1 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 CBZ27426.1 - 0.0014 18.6 0.0 0.0028 17.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_14 PF13173.6 CBZ27426.1 - 0.0029 17.6 0.0 0.0057 16.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 CBZ27426.1 - 0.0085 16.6 0.0 0.067 13.7 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 CBZ27426.1 - 0.0096 16.2 0.0 0.031 14.6 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 CBZ27426.1 - 0.02 15.3 0.0 0.052 13.9 0.0 1.8 1 0 0 1 1 1 0 AAA ATPase domain AAA_28 PF13521.6 CBZ27426.1 - 0.025 14.8 0.1 0.54 10.5 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 CBZ27426.1 - 0.03 14.5 0.8 0.078 13.1 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 CBZ27426.1 - 0.046 13.2 0.0 0.38 10.2 0.0 2.1 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_assoc_2 PF16193.5 CBZ27426.1 - 0.064 13.6 0.0 0.23 11.8 0.0 2.0 1 0 0 1 1 1 0 AAA C-terminal domain NTPase_1 PF03266.15 CBZ27426.1 - 0.07 13.0 0.0 0.13 12.1 0.0 1.4 1 0 0 1 1 1 0 NTPase RNA_helicase PF00910.22 CBZ27426.1 - 0.076 13.4 0.0 0.19 12.1 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA_6 PF12774.7 CBZ27426.1 - 0.15 11.0 0.0 0.25 10.3 0.0 1.3 1 0 0 1 1 1 0 Hydrolytic ATP binding site of dynein motor region PAP1 PF08601.10 CBZ27426.1 - 0.6 9.8 20.3 0.95 9.1 20.3 1.3 1 0 0 1 1 1 0 Transcription factor PAP1 Mnd1 PF03962.15 CBZ27428.1 - 3.1e-16 59.4 0.0 6.5e-16 58.4 0.0 1.5 1 0 0 1 1 1 1 Mnd1 HTH domain LZ3wCH PF18517.1 CBZ27428.1 - 2.9e-05 24.1 0.0 6.9e-05 22.9 0.0 1.7 1 0 0 1 1 1 1 Leucine zipper with capping helix domain Kelch_4 PF13418.6 CBZ27429.1 - 2.2e-15 56.4 0.1 6.9e-06 26.0 0.0 4.0 3 0 0 3 3 3 2 Galactose oxidase, central domain Kelch_6 PF13964.6 CBZ27429.1 - 5.1e-15 55.1 4.4 4.8e-05 23.5 0.0 4.0 4 0 0 4 4 4 3 Kelch motif Kelch_1 PF01344.25 CBZ27429.1 - 7.4e-10 38.3 5.6 9.7e-05 21.9 0.1 4.2 4 0 0 4 4 4 2 Kelch motif Kelch_5 PF13854.6 CBZ27429.1 - 7.5e-09 35.4 0.3 0.002 18.0 0.0 3.2 3 0 0 3 3 3 2 Kelch motif F-box-like PF12937.7 CBZ27429.1 - 2.1e-06 27.5 0.1 5.3e-06 26.2 0.1 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 CBZ27429.1 - 1.2e-05 25.0 0.1 3.2e-05 23.7 0.1 1.7 1 0 0 1 1 1 1 F-box domain Kelch_3 PF13415.6 CBZ27429.1 - 2.7e-05 24.3 1.1 1.2 9.6 0.2 4.1 3 0 0 3 3 3 2 Galactose oxidase, central domain Kelch_2 PF07646.15 CBZ27429.1 - 0.0016 18.3 0.3 0.76 9.9 0.0 3.3 3 0 0 3 3 3 1 Kelch motif LRR_4 PF12799.7 CBZ27430.1 - 1.5e-12 47.5 9.8 4.1e-07 30.2 0.5 3.1 1 1 1 3 3 3 3 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 CBZ27430.1 - 1.7e-11 43.9 6.4 9.4e-09 35.0 0.9 2.4 1 1 1 2 2 2 2 Leucine-rich repeat LRR_8 PF13855.6 CBZ27430.1 - 4.6e-09 35.9 5.4 6e-07 29.1 0.6 2.8 2 1 2 4 4 4 3 Leucine rich repeat FNIP PF05725.12 CBZ27430.1 - 0.033 14.3 0.3 0.085 13.0 0.3 1.6 1 0 0 1 1 1 0 FNIP Repeat UCR_14kD PF02271.16 CBZ27430.1 - 0.035 14.1 0.2 0.072 13.1 0.2 1.5 1 0 0 1 1 1 0 Ubiquinol-cytochrome C reductase complex 14kD subunit LRR_1 PF00560.33 CBZ27430.1 - 0.47 11.2 4.9 20 6.2 0.8 3.4 2 2 0 2 2 2 0 Leucine Rich Repeat Rubredoxin PF00301.20 CBZ27431.1 - 0.52 10.4 0.0 0.52 10.4 0.0 3.0 4 0 0 4 4 4 0 Rubredoxin DUF4936 PF16290.5 CBZ27431.1 - 1.6 9.5 6.6 1.3 9.7 0.1 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4936) SNF2_N PF00176.23 CBZ27432.1 - 2.1e-33 115.5 0.1 3e-32 111.7 0.0 2.3 2 1 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.31 CBZ27432.1 - 4.5e-14 52.7 0.0 2.1e-13 50.6 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 CBZ27432.1 - 0.0012 18.9 0.0 0.083 12.9 0.0 2.9 3 1 0 3 3 3 1 Type III restriction enzyme, res subunit SWI2_SNF2 PF18766.1 CBZ27432.1 - 0.0054 16.4 0.0 0.017 14.8 0.0 1.8 2 0 0 2 2 2 1 SWI2/SNF2 ATPase Cwf_Cwc_15 PF04889.12 CBZ27432.1 - 0.06 13.1 9.4 0.057 13.1 1.0 2.4 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein UBA2_C PF16195.5 CBZ27432.1 - 0.34 11.6 5.2 2.8 8.7 5.2 2.7 1 0 0 1 1 1 0 SUMO-activating enzyme subunit 2 C-terminus Dishevelled PF02377.15 CBZ27432.1 - 0.4 11.1 11.4 0.053 14.0 6.3 2.2 2 0 0 2 2 2 0 Dishevelled specific domain AKAP7_NLS PF10469.9 CBZ27433.1 - 4e-16 59.5 0.0 1e-15 58.2 0.0 1.6 1 1 0 1 1 1 1 AKAP7 2'5' RNA ligase-like domain DnaJ PF00226.31 CBZ27435.1 - 3.3e-14 52.8 0.1 2e-13 50.3 0.0 2.3 3 0 0 3 3 3 1 DnaJ domain Flavi_DEAD PF07652.14 CBZ27435.1 - 0.093 12.7 0.0 0.19 11.7 0.0 1.4 1 0 0 1 1 1 0 Flavivirus DEAD domain SR-25 PF10500.9 CBZ27435.1 - 0.19 11.3 5.3 0.4 10.3 5.3 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein IMUP PF15761.5 CBZ27435.1 - 7.4 7.3 9.4 0.58 10.9 4.1 1.8 2 0 0 2 2 2 0 Immortalisation up-regulated protein DUF962 PF06127.11 CBZ27436.1 - 0.22 11.6 10.1 0.19 11.8 2.7 3.3 3 1 0 3 3 3 0 Protein of unknown function (DUF962) DUF2534 PF10749.9 CBZ27436.1 - 4.8 7.4 9.3 7.4 6.8 5.1 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2534) HA2 PF04408.23 CBZ27437.1 - 4.9e-13 49.3 0.0 4.9e-13 49.3 0.0 2.7 3 0 0 3 3 3 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 CBZ27437.1 - 1e-10 41.8 0.0 2.3e-10 40.7 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 CBZ27437.1 - 2.6e-09 37.4 0.0 7.3e-09 36.0 0.0 1.8 1 1 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 CBZ27437.1 - 1.5e-05 24.9 0.0 3.2e-05 23.8 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_30 PF13604.6 CBZ27437.1 - 0.0013 18.5 0.1 0.0036 17.0 0.1 1.7 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 CBZ27437.1 - 0.003 17.8 1.4 0.019 15.2 0.7 2.7 2 1 0 2 2 2 1 AAA domain AAA_19 PF13245.6 CBZ27437.1 - 0.0056 17.0 0.2 0.015 15.6 0.1 1.7 2 0 0 2 2 2 1 AAA domain AAA_23 PF13476.6 CBZ27437.1 - 0.018 15.5 0.2 0.24 11.9 0.0 2.2 2 0 0 2 2 2 0 AAA domain cobW PF02492.19 CBZ27437.1 - 0.088 12.4 0.2 0.34 10.5 0.1 2.0 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain ABC_tran PF00005.27 CBZ27437.1 - 0.15 12.6 0.0 0.46 11.0 0.0 1.9 1 0 0 1 1 1 0 ABC transporter FH2 PF02181.23 CBZ27438.1 - 3.3e-49 168.0 0.0 4.4e-49 167.6 0.0 1.1 1 0 0 1 1 1 1 Formin Homology 2 Domain PTEN_C2 PF10409.9 CBZ27438.1 - 0.0047 16.7 0.0 0.013 15.2 0.0 1.7 2 0 0 2 2 2 1 C2 domain of PTEN tumour-suppressor protein APG6_N PF17675.1 CBZ27441.1 - 0.00017 22.2 17.2 0.00051 20.6 6.6 7.1 6 1 1 7 7 7 2 Apg6 coiled-coil region Fez1 PF06818.15 CBZ27441.1 - 0.00029 21.3 10.6 0.00029 21.3 10.6 4.9 3 1 2 5 5 5 2 Fez1 ATG16 PF08614.11 CBZ27441.1 - 0.00096 19.4 5.8 0.00096 19.4 5.8 6.1 5 1 0 5 5 5 3 Autophagy protein 16 (ATG16) CC2-LZ PF16516.5 CBZ27441.1 - 0.01 16.2 6.6 0.01 16.2 6.6 8.0 6 2 1 7 7 7 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator DUF3316 PF11777.8 CBZ27441.1 - 0.64 10.1 3.7 0.2 11.7 0.3 2.0 2 1 0 2 2 2 0 Protein of unknown function (DUF3316) Pox_A_type_inc PF04508.12 CBZ27441.1 - 7.5 6.6 8.1 16 5.6 0.0 4.2 4 0 0 4 4 4 0 Viral A-type inclusion protein repeat EF-hand_1 PF00036.32 CBZ27442.1 - 0.18 11.4 0.0 13 5.6 0.0 2.5 2 0 0 2 2 2 0 EF hand RNA_pol PF00940.19 CBZ27443.1 - 2.3e-131 438.4 0.0 4.1e-131 437.7 0.0 1.4 1 0 0 1 1 1 1 DNA-dependent RNA polymerase Prominin PF05478.11 CBZ27444.1 - 0.044 11.8 4.7 0.066 11.2 4.7 1.2 1 0 0 1 1 1 0 Prominin Syntaxin PF00804.25 CBZ27444.1 - 0.18 11.4 13.0 1.8 8.2 5.6 2.8 2 0 0 2 2 2 0 Syntaxin DUF2576 PF10845.8 CBZ27444.1 - 0.19 11.4 0.6 0.7 9.6 0.6 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2576) Adaptin_binding PF10199.9 CBZ27445.1 - 8.4e-06 26.4 0.0 0.082 13.5 0.0 3.4 3 1 0 3 3 3 2 Alpha and gamma adaptin binding protein p34 SURF6 PF04935.12 CBZ27446.1 - 4.5e-15 56.0 16.4 4.5e-15 56.0 16.4 1.8 1 1 1 2 2 2 1 Surfeit locus protein 6 GTSE1_N PF15259.6 CBZ27446.1 - 1.7 8.8 5.9 2.6 8.2 5.9 1.3 1 0 0 1 1 1 0 G-2 and S-phase expressed 1 Bax1-I PF01027.20 CBZ27447.1 - 1.1e-40 139.6 18.5 1.7e-40 139.1 18.5 1.2 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 BaxI_1 PF12811.7 CBZ27447.1 - 1.4e-09 37.8 6.1 2.1e-09 37.3 6.1 1.2 1 0 0 1 1 1 1 Bax inhibitor 1 like YL1 PF05764.13 CBZ27448.1 - 3.8e-09 37.0 20.2 3.8e-09 37.0 20.2 2.1 1 1 1 2 2 2 2 YL1 nuclear protein Spt5_N PF11942.8 CBZ27448.1 - 8.1 7.5 30.4 1.7 9.7 2.3 2.9 3 1 0 3 3 3 0 Spt5 transcription elongation factor, acidic N-terminal SUI1 PF01253.22 CBZ27449.1 - 1.4e-21 76.8 0.2 1.8e-21 76.4 0.2 1.1 1 0 0 1 1 1 1 Translation initiation factor SUI1 RRM_1 PF00076.22 CBZ27450.1 - 0.006 16.4 0.0 0.016 15.0 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Spuma_A9PTase PF03539.14 CBZ27450.1 - 0.098 12.8 0.0 0.16 12.1 0.0 1.2 1 0 0 1 1 1 0 Spumavirus aspartic protease (A9) Acetyltransf_7 PF13508.7 CBZ27451.1 - 1.3e-05 25.5 0.0 3.3e-05 24.2 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain PHD PF00628.29 CBZ27451.1 - 2.8e-05 23.9 10.3 5.2e-05 23.0 10.3 1.5 1 0 0 1 1 1 1 PHD-finger Acetyltransf_10 PF13673.7 CBZ27451.1 - 0.004 17.1 0.3 0.4 10.6 0.1 2.3 1 1 1 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 CBZ27451.1 - 0.24 11.5 0.5 0.96 9.5 0.1 2.1 1 1 1 2 2 2 0 Acetyltransferase (GNAT) domain Tristanin_u2 PF16638.5 CBZ27451.1 - 0.98 10.3 6.4 2.1 9.2 6.4 1.5 1 0 0 1 1 1 0 Unstructured region on methyltransferase between zinc-fingers PHD_4 PF16866.5 CBZ27451.1 - 7.4 6.7 11.8 0.16 12.1 5.1 1.7 2 0 0 2 2 2 0 PHD-finger Amastin PF07344.11 CBZ27453.1 - 2.5e-35 121.6 10.8 3.3e-35 121.2 10.8 1.1 1 0 0 1 1 1 1 Amastin surface glycoprotein Peptidase_C7 PF01830.18 CBZ27453.1 - 0.0022 17.4 0.2 0.0046 16.4 0.0 1.6 2 0 0 2 2 2 1 Peptidase C7 family TMEM100 PF16311.5 CBZ27453.1 - 1.3 8.6 5.6 0.55 9.8 3.3 1.5 2 0 0 2 2 2 0 Transmembrane protein 100 Amastin PF07344.11 CBZ27454.1 - 2.5e-42 144.4 13.8 3e-42 144.1 13.8 1.1 1 0 0 1 1 1 1 Amastin surface glycoprotein DUF3681 PF12442.8 CBZ27454.1 - 0.025 15.1 1.4 0.048 14.1 1.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3681) Amastin PF07344.11 CBZ27455.1 - 7.5e-42 142.8 17.8 8.7e-42 142.6 17.8 1.0 1 0 0 1 1 1 1 Amastin surface glycoprotein Amastin PF07344.11 CBZ27456.1 - 2.5e-35 121.6 10.8 3.3e-35 121.2 10.8 1.1 1 0 0 1 1 1 1 Amastin surface glycoprotein Peptidase_C7 PF01830.18 CBZ27456.1 - 0.0022 17.4 0.2 0.0046 16.4 0.0 1.6 2 0 0 2 2 2 1 Peptidase C7 family TMEM100 PF16311.5 CBZ27456.1 - 1.5 8.5 5.7 0.55 9.8 3.3 1.5 2 0 0 2 2 2 0 Transmembrane protein 100 WASH-7_mid PF14744.6 CBZ27457.1 - 2.8e-131 437.7 0.1 4.7e-131 437.0 0.1 1.3 1 0 0 1 1 1 1 WASH complex subunit 7 WASH-7_C PF14746.6 CBZ27457.1 - 1.3e-46 158.4 0.1 3.1e-46 157.2 0.1 1.7 1 0 0 1 1 1 1 WASH complex subunit 7, C-terminal WASH-7_N PF14745.6 CBZ27457.1 - 9.1e-24 83.9 0.0 1.1e-12 47.3 0.0 2.2 2 0 0 2 2 2 2 WASH complex subunit 7, N-terminal PGA2 PF07543.12 CBZ27457.1 - 0.062 13.3 0.2 0.17 11.9 0.2 1.7 1 0 0 1 1 1 0 Protein trafficking PGA2 DnaJ PF00226.31 CBZ27458.1 - 6.7e-10 38.9 0.0 1.4e-09 37.9 0.0 1.4 1 0 0 1 1 1 1 DnaJ domain PAS PF00989.25 CBZ27458.1 - 0.092 12.8 0.0 0.23 11.5 0.0 1.6 1 0 0 1 1 1 0 PAS fold BLUF PF04940.12 CBZ27459.1 - 0.076 13.1 0.0 0.32 11.2 0.0 1.9 2 0 0 2 2 2 0 Sensors of blue-light using FAD Pro_isomerase PF00160.21 CBZ27460.1 - 5.5e-20 72.2 0.0 7.3e-20 71.8 0.0 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD TRAPP PF04051.16 CBZ27461.1 - 2.6e-05 24.0 0.0 3.1e-05 23.7 0.0 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component LRR_9 PF14580.6 CBZ27461.1 - 0.16 11.4 0.0 0.22 11.0 0.0 1.1 1 0 0 1 1 1 0 Leucine-rich repeat GTP_EFTU PF00009.27 CBZ27463.1 - 1.7e-22 79.9 0.5 2.6e-20 72.8 0.5 2.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 CBZ27463.1 - 2.2e-11 43.8 0.1 6e-11 42.4 0.1 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase IF-2 PF11987.8 CBZ27463.1 - 5e-05 23.4 0.0 0.00012 22.2 0.0 1.5 1 0 0 1 1 1 1 Translation-initiation factor 2 PduV-EutP PF10662.9 CBZ27463.1 - 5.9e-05 22.8 0.1 0.00038 20.2 0.0 2.3 2 1 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation Dynamin_N PF00350.23 CBZ27463.1 - 0.0057 16.7 0.0 0.04 14.0 0.0 2.3 1 1 1 2 2 2 1 Dynamin family RsgA_GTPase PF03193.16 CBZ27463.1 - 0.0092 15.9 0.1 1.2 9.0 0.1 2.5 2 0 0 2 2 2 1 RsgA GTPase SRPRB PF09439.10 CBZ27463.1 - 0.012 15.0 0.0 0.052 13.0 0.0 1.9 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit FeoB_N PF02421.18 CBZ27463.1 - 0.017 14.7 0.0 0.036 13.6 0.0 1.5 1 0 0 1 1 1 0 Ferrous iron transport protein B cobW PF02492.19 CBZ27463.1 - 0.17 11.4 1.0 1.6 8.3 0.1 2.8 2 1 1 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain IQ PF00612.27 CBZ27464.1 - 1.2e-06 27.7 46.4 0.0004 19.9 1.0 7.6 6 1 1 7 7 7 5 IQ calmodulin-binding motif Dymeclin PF09742.9 CBZ27465.1 - 5.1e-58 197.0 0.0 6.6e-58 196.6 0.0 1.1 1 0 0 1 1 1 1 Dyggve-Melchior-Clausen syndrome protein Hid1 PF12722.7 CBZ27465.1 - 4.7e-26 91.2 6.4 2e-14 52.7 1.7 4.4 4 1 0 4 4 4 3 High-temperature-induced dauer-formation protein Hist_deacetyl PF00850.19 CBZ27466.1 - 1.9e-72 244.3 0.2 2.5e-72 244.0 0.2 1.1 1 0 0 1 1 1 1 Histone deacetylase domain EF-hand_7 PF13499.6 CBZ27467.1 - 2e-21 76.2 5.9 1.3e-12 48.0 0.6 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 CBZ27467.1 - 3.9e-18 63.6 5.7 8.3e-05 21.9 0.4 4.3 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.6 CBZ27467.1 - 5.7e-16 57.0 7.3 0.00087 19.0 0.1 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 CBZ27467.1 - 1.8e-14 52.5 5.6 6.2e-05 22.3 0.1 4.2 4 0 0 4 4 4 4 EF hand zf-C3HC4_3 PF13920.6 CBZ27467.1 - 8e-11 41.6 6.0 8e-11 41.6 6.0 1.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 CBZ27467.1 - 8.8e-09 35.1 10.2 2.2e-08 33.8 10.2 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CBZ27467.1 - 1.9e-08 34.2 2.2 1.9e-08 34.2 2.2 2.9 3 0 0 3 3 3 1 RING-type zinc-finger EF-hand_8 PF13833.6 CBZ27467.1 - 3.7e-08 33.1 7.9 0.0019 18.0 0.2 3.9 2 2 2 4 4 4 2 EF-hand domain pair zf-RING_5 PF14634.6 CBZ27467.1 - 1.5e-07 31.3 6.1 1.5e-07 31.3 6.1 2.3 3 0 0 3 3 3 1 zinc-RING finger domain Prok-RING_4 PF14447.6 CBZ27467.1 - 4.4e-07 29.6 6.6 1.3e-06 28.1 6.6 1.8 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.25 CBZ27467.1 - 5.4e-07 29.4 7.0 5.4e-07 29.4 7.0 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CBZ27467.1 - 7e-07 29.5 8.2 7e-07 29.5 8.2 2.0 2 0 0 2 2 1 1 Ring finger domain SPARC_Ca_bdg PF10591.9 CBZ27467.1 - 1.2e-06 28.8 0.1 0.00014 22.1 0.0 2.4 2 0 0 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region zf-RING_6 PF14835.6 CBZ27467.1 - 9e-06 25.5 2.8 2.2e-05 24.2 2.8 1.7 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-C3HC4_4 PF15227.6 CBZ27467.1 - 0.00051 20.1 4.8 0.00051 20.1 4.8 2.5 2 1 1 3 3 2 1 zinc finger of C3HC4-type, RING zf-RING_11 PF17123.5 CBZ27467.1 - 0.0031 17.2 4.6 0.022 14.5 3.2 2.4 2 0 0 2 2 2 1 RING-like zinc finger EF-hand_11 PF08976.11 CBZ27467.1 - 0.061 14.2 0.6 16 6.4 0.1 2.3 1 1 1 2 2 2 0 EF-hand domain zf-RING_10 PF16685.5 CBZ27467.1 - 0.17 12.1 9.6 0.28 11.3 8.9 1.8 1 1 0 1 1 1 0 zinc RING finger of MSL2 EF-hand_10 PF14788.6 CBZ27467.1 - 0.17 11.8 0.5 27 4.7 0.0 3.2 3 1 1 4 4 4 0 EF hand DZR PF12773.7 CBZ27467.1 - 3.1 7.9 12.6 58 3.8 12.7 2.6 1 1 0 1 1 1 0 Double zinc ribbon G_path_suppress PF15991.5 CBZ27467.1 - 4.9 7.2 14.9 9.2 6.3 14.9 1.4 1 0 0 1 1 1 0 G-protein pathway suppressor EF-hand_7 PF13499.6 CBZ27468.1 - 2.9e-22 78.9 7.0 1.9e-13 50.7 0.6 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 CBZ27468.1 - 1.2e-18 65.2 6.9 3.4e-05 23.1 0.0 4.3 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.6 CBZ27468.1 - 1.1e-16 59.2 8.1 0.00028 20.6 0.1 4.2 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 CBZ27468.1 - 1.1e-14 53.2 6.3 2.2e-05 23.7 0.1 4.2 4 0 0 4 4 4 4 EF hand zf-C3HC4_3 PF13920.6 CBZ27468.1 - 6.3e-11 42.0 6.0 6.3e-11 42.0 6.0 1.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 CBZ27468.1 - 6.5e-09 35.5 10.2 1.7e-08 34.1 10.2 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CBZ27468.1 - 1.5e-08 34.5 2.2 1.5e-08 34.5 2.2 2.9 3 0 0 3 3 3 1 RING-type zinc-finger EF-hand_8 PF13833.6 CBZ27468.1 - 3e-08 33.4 8.8 0.021 14.7 0.2 4.1 3 1 1 4 4 4 2 EF-hand domain pair zf-RING_5 PF14634.6 CBZ27468.1 - 1.2e-07 31.6 6.1 1.2e-07 31.6 6.1 1.9 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4 PF00097.25 CBZ27468.1 - 2.8e-07 30.3 6.5 2.8e-07 30.3 6.5 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 CBZ27468.1 - 3.8e-07 29.9 6.7 1.2e-06 28.3 6.7 1.8 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 CBZ27468.1 - 5.6e-07 29.8 8.2 5.6e-07 29.8 8.2 2.1 2 0 0 2 2 2 1 Ring finger domain SPARC_Ca_bdg PF10591.9 CBZ27468.1 - 9.5e-07 29.1 0.1 5.6e-05 23.4 0.0 2.3 2 0 0 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region zf-RING_6 PF14835.6 CBZ27468.1 - 5.8e-06 26.1 2.8 1.7e-05 24.6 2.8 1.8 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-C3HC4_4 PF15227.6 CBZ27468.1 - 0.00038 20.5 4.7 0.00038 20.5 4.7 2.5 2 1 1 3 3 3 1 zinc finger of C3HC4-type, RING zf-RING_11 PF17123.5 CBZ27468.1 - 0.0021 17.7 4.6 0.018 14.8 3.2 2.5 2 0 0 2 2 2 1 RING-like zinc finger EF-hand_11 PF08976.11 CBZ27468.1 - 0.04 14.8 0.5 9 7.2 0.1 2.3 1 1 1 2 2 2 0 EF-hand domain EF-hand_10 PF14788.6 CBZ27468.1 - 0.061 13.2 0.7 22 5.0 0.0 3.3 3 1 1 4 4 4 0 EF hand zf-RING_10 PF16685.5 CBZ27468.1 - 0.095 12.9 9.0 0.23 11.6 9.0 1.7 1 1 0 1 1 1 0 zinc RING finger of MSL2 Mu-like_Com PF10122.9 CBZ27468.1 - 1.6 8.3 4.9 7.7 6.1 0.0 2.4 2 0 0 2 2 2 0 Mu-like prophage protein Com DZR PF12773.7 CBZ27468.1 - 3.2 7.8 13.2 71 3.5 13.4 2.5 1 1 0 1 1 1 0 Double zinc ribbon Atg14 PF10186.9 CBZ27469.1 - 0.85 8.6 16.9 1.5 7.8 16.9 1.5 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF16 PF01519.16 CBZ27469.1 - 0.96 10.0 10.0 2.6 8.6 5.1 2.8 1 1 2 3 3 3 0 Protein of unknown function DUF16 DUF641 PF04859.12 CBZ27469.1 - 2 8.8 17.7 0.53 10.6 5.3 3.0 1 1 2 3 3 3 0 Plant protein of unknown function (DUF641) DUF4407 PF14362.6 CBZ27469.1 - 2 7.7 19.9 4.3 6.6 19.9 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) NRBF2 PF08961.10 CBZ27469.1 - 4.5 6.8 14.1 0.054 13.1 2.7 2.2 1 1 1 2 2 2 0 Nuclear receptor-binding factor 2, autophagy regulator Mlh1_C PF16413.5 CBZ27471.1 - 7.8e-30 104.2 0.0 1.8e-10 40.6 0.0 3.3 3 0 0 3 3 3 3 DNA mismatch repair protein Mlh1 C-terminus DNA_mis_repair PF01119.19 CBZ27471.1 - 5.5e-23 80.9 0.0 1.1e-22 79.9 0.0 1.4 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.6 CBZ27471.1 - 5.2e-09 36.1 0.0 1.1e-08 35.0 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 CBZ27471.1 - 4.9e-05 23.8 0.0 0.00011 22.6 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Kinesin PF00225.23 CBZ27472.1 - 1.1e-58 198.7 0.1 7.7e-40 136.8 0.0 2.2 2 0 0 2 2 2 2 Kinesin motor domain Microtub_bd PF16796.5 CBZ27472.1 - 6.7e-12 45.6 0.4 1.5e-11 44.4 0.1 1.7 2 0 0 2 2 2 1 Microtubule binding GIT_CC PF16559.5 CBZ27472.1 - 0.17 11.8 1.0 0.54 10.2 1.0 1.9 1 0 0 1 1 1 0 GIT coiled-coil Rho guanine nucleotide exchange factor DivIC PF04977.15 CBZ27472.1 - 0.6 9.9 5.0 1.7 8.5 5.0 1.8 1 0 0 1 1 1 0 Septum formation initiator DUF563 PF04577.14 CBZ27474.1 - 2e-09 37.9 0.0 3.4e-09 37.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF563) HpcH_HpaI PF03328.14 CBZ27475.1 - 1.6e-21 76.5 0.0 8.3e-10 38.2 0.0 3.0 2 1 0 2 2 2 2 HpcH/HpaI aldolase/citrate lyase family C-C_Bond_Lyase PF15617.6 CBZ27475.1 - 6.8e-13 48.5 0.0 1.4e-06 27.7 0.0 2.1 2 0 0 2 2 2 2 C-C_Bond_Lyase of the TIM-Barrel fold Pkinase PF00069.25 CBZ27476.1 - 3.2e-64 216.9 0.0 4.1e-64 216.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ27476.1 - 6.3e-41 140.4 0.0 9.3e-41 139.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CBZ27476.1 - 1.1e-05 24.4 0.0 1.7e-05 23.8 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 CBZ27476.1 - 2.1e-05 24.0 0.0 5.2e-05 22.7 0.0 1.6 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 CBZ27476.1 - 0.0031 17.5 0.0 0.19 11.6 0.1 2.8 1 1 2 3 3 3 1 Phosphotransferase enzyme family DZR PF12773.7 CBZ27476.1 - 0.0069 16.4 0.7 0.014 15.4 0.7 1.5 1 0 0 1 1 1 1 Double zinc ribbon FTA2 PF13095.6 CBZ27476.1 - 0.011 15.3 0.0 0.019 14.6 0.0 1.3 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 NOB1_Zn_bind PF08772.11 CBZ27476.1 - 0.016 15.3 0.6 0.031 14.5 0.6 1.4 1 0 0 1 1 1 0 Nin one binding (NOB1) Zn-ribbon like zinc_ribbon_2 PF13240.6 CBZ27476.1 - 0.12 12.1 3.6 0.36 10.6 3.6 1.8 1 1 0 1 1 1 0 zinc-ribbon domain Kinase-like PF14531.6 CBZ27476.1 - 0.15 11.3 0.0 0.24 10.7 0.0 1.2 1 0 0 1 1 1 0 Kinase-like zf-ribbon_3 PF13248.6 CBZ27476.1 - 0.15 11.5 1.4 0.34 10.4 1.4 1.5 1 0 0 1 1 1 0 zinc-ribbon domain zf-NADH-PPase PF09297.11 CBZ27476.1 - 0.97 9.2 11.4 0.46 10.2 3.9 2.5 2 0 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain ABC_tran PF00005.27 CBZ27477.1 - 5.9e-22 78.7 0.0 6.3e-08 33.2 0.0 4.6 4 0 0 4 4 4 4 ABC transporter ABC_membrane PF00664.23 CBZ27477.1 - 5.6e-17 62.3 9.7 5e-10 39.5 9.0 2.5 2 0 0 2 2 2 2 ABC transporter transmembrane region RsgA_GTPase PF03193.16 CBZ27477.1 - 0.22 11.4 0.5 2.1 8.3 0.2 2.2 2 0 0 2 2 2 0 RsgA GTPase Dynamin_N PF00350.23 CBZ27477.1 - 2 8.4 3.7 1.5 8.8 1.1 2.0 2 0 0 2 2 2 0 Dynamin family WD40 PF00400.32 CBZ27479.1 - 0.011 16.6 0.2 1.1e+02 3.9 0.1 5.6 5 0 0 5 5 5 0 WD domain, G-beta repeat Focadhesin PF11229.8 CBZ27479.1 - 0.066 11.4 0.1 0.1 10.8 0.1 1.2 1 0 0 1 1 1 0 Focadhesin DUF3586 PF12131.8 CBZ27479.1 - 4.7 7.5 9.7 47 4.3 9.7 2.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3586) START PF01852.19 CBZ27480.1 - 8.2e-05 22.1 0.1 0.17 11.3 0.0 3.1 3 0 0 3 3 3 3 START domain DUF2921 PF11145.8 CBZ27480.1 - 0.15 9.9 0.0 0.21 9.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2921) WD40 PF00400.32 CBZ27481.1 - 5.7e-08 33.3 1.6 0.0024 18.6 0.1 4.6 4 0 0 4 4 4 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBZ27481.1 - 0.0017 18.6 0.0 0.21 11.9 0.0 3.0 3 0 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain FYDLN_acid PF09538.10 CBZ27481.1 - 0.21 12.3 4.9 0.37 11.5 4.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) DUF2722 PF10846.8 CBZ27481.1 - 3.1 6.6 4.2 4.7 6.0 4.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) TCTP PF00838.17 CBZ27482.1 - 4.4e-43 147.5 0.6 5.2e-43 147.3 0.6 1.1 1 0 0 1 1 1 1 Translationally controlled tumour protein ERCC4 PF02732.15 CBZ27483.1 - 1e-10 42.0 0.0 1.8e-10 41.2 0.0 1.4 1 0 0 1 1 1 1 ERCC4 domain SAP PF02037.27 CBZ27483.1 - 1.2e-05 24.9 0.2 2.9e-05 23.7 0.2 1.7 1 0 0 1 1 1 1 SAP domain RecQ_Zn_bind PF16124.5 CBZ27484.1 - 7e-16 58.7 0.0 2.1e-15 57.2 0.0 1.9 1 0 0 1 1 1 1 RecQ zinc-binding DEAD PF00270.29 CBZ27484.1 - 6.6e-15 55.3 0.0 3.5e-14 52.9 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CBZ27484.1 - 1.6e-13 50.9 0.0 2.6e-12 47.1 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain HRDC PF00570.23 CBZ27484.1 - 1.3e-05 25.0 0.0 2.8e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 HRDC domain Choline_kin_N PF04428.14 CBZ27484.1 - 0.063 13.0 0.0 0.17 11.6 0.0 1.7 1 0 0 1 1 1 0 Choline kinase N terminus GreA_GreB_N PF03449.15 CBZ27484.1 - 0.11 12.7 0.9 0.29 11.3 0.9 1.7 1 0 0 1 1 1 0 Transcription elongation factor, N-terminal Clat_adaptor_s PF01217.20 CBZ27485.1 - 2e-44 150.9 0.8 2.4e-44 150.7 0.8 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain MRG PF05712.13 CBZ27485.1 - 0.023 14.0 0.0 0.023 14.0 0.0 1.2 1 0 0 1 1 1 0 MRG Glu_synthase PF01645.17 CBZ27486.1 - 0.059 12.5 0.0 0.11 11.6 0.0 1.4 1 0 0 1 1 1 0 Conserved region in glutamate synthase LRR_6 PF13516.6 CBZ27487.1 - 0.008 16.2 0.2 1.9 8.7 0.0 3.1 3 0 0 3 3 3 1 Leucine Rich repeat EF-hand_6 PF13405.6 CBZ27487.1 - 0.018 15.0 0.2 7.9 6.7 0.0 3.2 3 0 0 3 3 3 0 EF-hand domain EF-hand_1 PF00036.32 CBZ27487.1 - 0.14 11.8 1.3 14 5.5 0.1 3.1 3 0 0 3 3 3 0 EF hand RRM_1 PF00076.22 CBZ27488.1 - 3.2e-31 106.9 1.9 1.3e-21 76.1 0.1 3.4 2 1 1 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 CBZ27488.1 - 1.3e-05 25.1 0.0 0.022 14.7 0.0 2.8 3 0 0 3 3 3 2 Nup53/35/40-type RNA recognition motif RRM_5 PF13893.6 CBZ27488.1 - 0.0015 18.1 0.0 0.0073 15.9 0.0 2.1 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.8 CBZ27488.1 - 0.0021 18.1 0.0 0.006 16.6 0.0 1.8 1 0 0 1 1 1 1 Limkain b1 RRM_7 PF16367.5 CBZ27488.1 - 0.004 17.2 0.0 1.6 8.9 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif RRM_occluded PF16842.5 CBZ27488.1 - 0.18 11.7 0.0 0.6 10.0 0.0 1.8 2 0 0 2 2 2 0 Occluded RNA-recognition motif PHM7_cyt PF14703.6 CBZ27488.1 - 6 7.1 10.0 8.6 6.6 0.0 3.4 5 1 1 6 6 6 0 Cytosolic domain of 10TM putative phosphate transporter UBA PF00627.31 CBZ27489.1 - 0.0014 18.5 0.3 0.0029 17.5 0.3 1.5 1 0 0 1 1 1 1 UBA/TS-N domain Rhomboid PF01694.22 CBZ27489.1 - 0.0039 17.2 1.2 0.01 15.8 1.2 1.7 1 1 0 1 1 1 1 Rhomboid family UBA_4 PF14555.6 CBZ27489.1 - 0.0087 15.9 0.0 0.02 14.7 0.0 1.6 1 0 0 1 1 1 1 UBA-like domain DUF2157 PF09925.9 CBZ27489.1 - 6.1 6.6 8.7 1.7 8.4 5.1 1.9 2 0 0 2 2 2 0 Predicted membrane protein (DUF2157) Methyltrn_RNA_2 PF04013.12 CBZ27491.1 - 0.022 14.5 0.1 0.024 14.4 0.1 1.0 1 0 0 1 1 1 0 Putative SAM-dependent RNA methyltransferase zf-rbx1 PF12678.7 CBZ27492.1 - 5e-21 74.7 13.0 7.3e-21 74.2 13.0 1.2 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 CBZ27492.1 - 3.8e-12 46.1 10.3 6.1e-12 45.4 9.1 1.8 1 1 1 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_2 PF13639.6 CBZ27492.1 - 1.4e-09 38.1 5.4 1.4e-09 38.1 5.4 2.2 1 1 1 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.25 CBZ27492.1 - 3.1e-06 26.9 10.9 4.8e-05 23.1 10.9 2.2 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 CBZ27492.1 - 0.00027 20.8 3.4 0.00027 20.8 3.4 2.2 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 CBZ27492.1 - 0.00097 18.9 15.6 0.022 14.6 15.6 2.4 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 CBZ27492.1 - 0.0021 17.8 13.1 0.45 10.3 13.1 2.4 1 1 0 1 1 1 1 RING-like zinc finger Zn_ribbon_17 PF17120.5 CBZ27492.1 - 0.007 16.0 15.9 0.088 12.4 4.7 2.2 1 1 1 2 2 2 2 Zinc-ribbon, C4HC2 type FANCL_C PF11793.8 CBZ27492.1 - 0.11 12.7 10.1 0.26 11.5 10.1 1.7 1 1 0 1 1 1 0 FANCL C-terminal domain zf-RING_UBOX PF13445.6 CBZ27492.1 - 0.11 12.5 13.4 0.65 10.1 13.4 2.1 1 1 0 1 1 1 0 RING-type zinc-finger zf-RING_5 PF14634.6 CBZ27492.1 - 0.17 11.8 12.7 1.2 9.2 12.7 2.1 1 1 0 1 1 1 0 zinc-RING finger domain zf-HC5HC2H_2 PF13832.6 CBZ27492.1 - 0.57 10.4 11.1 1 9.5 11.1 1.5 1 1 0 1 1 1 0 PHD-zinc-finger like domain GST_N_4 PF17172.4 CBZ27493.1 - 1e-14 55.1 0.0 2.3e-14 53.9 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase N-terminal domain Tom37 PF10568.9 CBZ27493.1 - 1.1e-07 32.2 0.0 4.6e-07 30.2 0.0 2.1 2 1 1 3 3 3 1 Outer mitochondrial membrane transport complex protein GST_C_6 PF17171.4 CBZ27493.1 - 1.4e-07 31.2 0.1 3e-07 30.1 0.1 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 CBZ27493.1 - 6.4e-05 22.9 0.0 0.00014 21.8 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Glutaredoxin PF00462.24 CBZ27493.1 - 0.019 15.1 0.0 0.046 13.9 0.0 1.6 1 0 0 1 1 1 0 Glutaredoxin FAD_binding_2 PF00890.24 CBZ27494.1 - 5.1e-117 391.5 2.8 3.1e-116 388.9 1.4 2.0 2 0 0 2 2 2 1 FAD binding domain Succ_DH_flav_C PF02910.20 CBZ27494.1 - 2.8e-41 140.5 1.9 3.9e-41 140.0 1.9 1.2 1 0 0 1 1 1 1 Fumarate reductase flavoprotein C-term Pyr_redox_2 PF07992.14 CBZ27494.1 - 0.001 18.4 1.0 0.0015 17.8 0.4 1.8 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 CBZ27494.1 - 0.0011 18.2 0.1 0.15 11.3 0.1 2.4 2 0 0 2 2 2 2 Thi4 family DAO PF01266.24 CBZ27494.1 - 0.007 16.0 0.4 0.05 13.2 0.4 2.0 1 1 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.14 CBZ27494.1 - 0.027 13.2 0.1 0.044 12.5 0.1 1.3 1 0 0 1 1 1 0 HI0933-like protein GIDA PF01134.22 CBZ27494.1 - 0.059 12.4 3.2 0.11 11.5 2.4 1.7 2 0 0 2 2 2 0 Glucose inhibited division protein A Lycopene_cycl PF05834.12 CBZ27494.1 - 0.13 11.3 2.7 1.7 7.6 0.5 2.2 2 0 0 2 2 2 0 Lycopene cyclase protein FAD_binding_3 PF01494.19 CBZ27494.1 - 0.22 10.7 2.7 0.62 9.2 0.3 2.3 2 0 0 2 2 2 0 FAD binding domain NAD_binding_4 PF07993.12 CBZ27495.1 - 2.2e-67 226.9 0.0 3e-67 226.5 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein Sterile PF03015.19 CBZ27495.1 - 8.7e-11 41.9 0.2 1.9e-10 40.8 0.2 1.6 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.21 CBZ27495.1 - 5.8e-06 25.9 0.3 5.3e-05 22.8 0.3 2.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 CBZ27495.1 - 0.0012 18.3 0.3 1.3 8.4 0.0 3.0 3 0 0 3 3 3 2 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 CBZ27495.1 - 0.021 13.9 0.0 0.77 8.8 0.0 2.7 3 0 0 3 3 3 0 RmlD substrate binding domain Semialdhyde_dh PF01118.24 CBZ27495.1 - 0.069 13.6 0.0 0.13 12.7 0.0 1.4 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Polysacc_synt_2 PF02719.15 CBZ27495.1 - 0.073 12.2 0.0 1.3 8.1 0.0 2.2 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein TMF_TATA_bd PF12325.8 CBZ27496.1 - 0.02 15.1 43.7 0.07 13.4 13.5 4.3 1 1 2 3 3 3 0 TATA element modulatory factor 1 TATA binding FlaC_arch PF05377.11 CBZ27496.1 - 0.077 13.4 12.0 0.66 10.4 0.1 4.5 4 0 0 4 4 4 0 Flagella accessory protein C (FlaC) DUF4515 PF14988.6 CBZ27496.1 - 0.63 9.8 49.1 0.22 11.3 26.5 3.2 1 1 1 3 3 3 0 Domain of unknown function (DUF4515) BRE1 PF08647.11 CBZ27496.1 - 1.6 8.9 34.7 1.6 8.9 0.3 4.1 3 2 1 4 4 4 0 BRE1 E3 ubiquitin ligase RasGAP_C PF03836.15 CBZ27496.1 - 9.3 6.4 30.1 2.5 8.3 1.3 4.1 1 1 2 3 3 3 0 RasGAP C-terminus SpoU_methylase PF00588.19 CBZ27497.1 - 2.2e-14 53.8 0.0 2.3e-12 47.2 0.0 2.7 2 1 0 2 2 2 1 SpoU rRNA Methylase family Pterin_4a PF01329.19 CBZ27498.1 - 0.057 13.6 1.2 0.82 9.9 0.0 2.8 3 1 0 3 3 3 0 Pterin 4 alpha carbinolamine dehydratase Ssl1 PF04056.14 CBZ27499.1 - 3.3e-18 66.2 0.2 5.8e-08 32.8 0.0 2.5 2 0 0 2 2 2 2 Ssl1-like VWA_2 PF13519.6 CBZ27499.1 - 3.6e-07 30.8 0.0 6.8e-07 29.9 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain DZR PF12773.7 CBZ27499.1 - 0.33 11.0 8.1 0.77 9.8 0.2 2.6 2 1 0 2 2 2 0 Double zinc ribbon Rubredoxin_2 PF18073.1 CBZ27499.1 - 0.35 10.6 11.1 0.29 10.9 0.6 3.5 3 0 0 3 3 3 0 Rubredoxin metal binding domain SET PF00856.28 CBZ27500.1 - 6.7e-11 42.9 0.1 1.4e-10 41.8 0.1 1.6 1 1 0 1 1 1 1 SET domain TPR_1 PF00515.28 CBZ27500.1 - 0.00029 20.5 4.4 0.00052 19.7 0.4 2.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.17 CBZ27500.1 - 0.012 15.7 3.9 0.02 15.0 0.4 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat zf-tcix PF14952.6 CBZ27500.1 - 0.026 14.2 1.8 0.026 14.2 1.8 3.3 4 0 0 4 4 4 0 Putative treble-clef, zinc-finger, Zn-binding DUF2116 PF09889.9 CBZ27500.1 - 3.8 7.6 6.8 12 6.0 6.9 1.9 1 1 0 1 1 1 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) Clathrin-link PF09268.10 CBZ27501.1 - 0.17 11.3 0.1 0.31 10.5 0.1 1.5 1 0 0 1 1 1 0 Clathrin, heavy-chain linker Ribosomal_S21 PF01165.20 CBZ27501.1 - 0.71 9.6 3.7 0.22 11.3 0.2 1.9 2 0 0 2 2 2 0 Ribosomal protein S21 UQ_con PF00179.26 CBZ27502.1 - 1.3e-18 67.0 0.0 2e-18 66.4 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 CBZ27502.1 - 0.001 18.7 0.0 0.002 17.8 0.0 1.5 1 1 1 2 2 2 1 Prokaryotic E2 family B SSI PF00720.17 CBZ27502.1 - 0.15 12.1 0.0 0.23 11.4 0.0 1.4 1 0 0 1 1 1 0 Subtilisin inhibitor-like WD40 PF00400.32 CBZ27503.1 - 1.4e-25 89.0 18.5 4e-06 27.5 0.0 7.3 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBZ27503.1 - 9.7e-22 77.1 1.7 2.5e-07 30.9 0.1 6.0 2 1 4 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 CBZ27503.1 - 2.2e-06 27.7 0.0 0.14 12.0 0.0 3.1 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 CBZ27503.1 - 0.0021 17.1 0.7 0.68 8.8 0.0 2.8 3 0 0 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Nbas_N PF15492.6 CBZ27503.1 - 0.022 14.1 0.2 1.3 8.3 0.0 2.7 1 1 2 3 3 3 0 Neuroblastoma-amplified sequence, N terminal IKI3 PF04762.12 CBZ27503.1 - 0.074 11.0 0.9 1.6 6.6 0.0 2.5 2 1 0 2 2 2 0 IKI3 family Pkinase PF00069.25 CBZ27504.1 - 3.8e-46 157.6 0.0 6.5e-46 156.8 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ27504.1 - 1.1e-25 90.4 0.0 2.6e-25 89.2 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase LRR_8 PF13855.6 CBZ27504.1 - 1.2e-06 28.2 2.5 5.5e-05 22.8 0.4 3.5 2 1 1 3 3 3 1 Leucine rich repeat LRR_4 PF12799.7 CBZ27504.1 - 3.3e-06 27.3 1.3 0.00071 19.9 0.2 2.8 3 0 0 3 3 2 1 Leucine Rich repeats (2 copies) Kinase-like PF14531.6 CBZ27504.1 - 0.00012 21.5 0.0 0.00044 19.6 0.0 1.8 2 0 0 2 2 2 1 Kinase-like zf-B_box PF00643.24 CBZ27504.1 - 0.0027 17.8 18.2 0.0091 16.1 3.1 2.7 2 0 0 2 2 2 2 B-box zinc finger C1_2 PF03107.16 CBZ27504.1 - 0.01 16.1 5.7 0.01 16.1 5.7 3.0 3 0 0 3 3 3 0 C1 domain zf-UBR PF02207.20 CBZ27504.1 - 0.012 15.7 2.0 0.012 15.7 2.0 3.1 3 0 0 3 3 3 0 Putative zinc finger in N-recognin (UBR box) LRR_1 PF00560.33 CBZ27504.1 - 0.039 14.5 1.5 18 6.3 0.1 3.7 3 0 0 3 3 3 0 Leucine Rich Repeat LRR_6 PF13516.6 CBZ27504.1 - 0.042 13.9 0.1 14 6.1 0.0 3.8 3 0 0 3 3 3 0 Leucine Rich repeat ZZ PF00569.17 CBZ27504.1 - 0.26 11.1 20.8 1.3 8.9 7.1 2.6 2 0 0 2 2 2 0 Zinc finger, ZZ type zf-H2C2_5 PF13909.6 CBZ27504.1 - 0.53 10.1 2.6 1.6 8.6 2.6 1.9 1 0 0 1 1 1 0 C2H2-type zinc-finger domain APH PF01636.23 CBZ27504.1 - 3.1 7.7 5.4 0.78 9.6 0.1 2.7 3 1 1 4 4 4 0 Phosphotransferase enzyme family GCV_T PF01571.21 CBZ27505.1 - 3.1e-08 33.3 0.0 4.7e-08 32.7 0.0 1.2 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain SET PF00856.28 CBZ27506.1 - 1.2e-08 35.6 0.0 4e-08 33.8 0.0 1.9 2 0 0 2 2 2 1 SET domain CGI-121 PF08617.10 CBZ27507.1 - 4.4e-05 23.7 0.0 9.1e-05 22.6 0.0 1.5 1 1 0 1 1 1 1 Kinase binding protein CGI-121 Inhibitor_I42 PF09394.10 CBZ27508.1 - 2.3e-18 66.4 0.0 2.8e-18 66.1 0.0 1.1 1 0 0 1 1 1 1 Chagasin family peptidase inhibitor I42 Inhibitor_I71 PF12628.7 CBZ27508.1 - 0.00097 19.0 0.3 1.2 9.0 0.1 2.0 1 1 0 2 2 2 2 Falstatin, cysteine peptidase inhibitor AMP-binding PF00501.28 CBZ27509.1 - 8.4e-12 44.4 4.7 0.00042 19.0 0.0 4.9 5 0 0 5 5 5 4 AMP-binding enzyme RRM_1 PF00076.22 CBZ27510.1 - 7.1e-16 57.8 0.1 1.5e-15 56.8 0.1 1.5 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 CBZ27510.1 - 0.013 15.0 0.0 0.025 14.2 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SPX PF03105.19 CBZ27510.1 - 0.13 12.2 6.8 0.15 11.9 6.8 1.1 1 0 0 1 1 1 0 SPX domain TFIIA PF03153.13 CBZ27510.1 - 0.18 11.8 25.0 0.23 11.4 25.0 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Nup35_RRM_2 PF14605.6 CBZ27510.1 - 0.18 11.8 0.0 0.47 10.5 0.0 1.7 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif DUF4551 PF15087.6 CBZ27510.1 - 2.5 6.8 6.4 3.2 6.5 6.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Ndc1_Nup PF09531.10 CBZ27510.1 - 4.1 6.0 13.4 5 5.7 13.4 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Lin-8 PF03353.15 CBZ27510.1 - 5.2 6.6 9.0 7.5 6.0 9.0 1.2 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist PAT1 PF09770.9 CBZ27510.1 - 6.6 4.9 19.4 8.3 4.5 19.4 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Mannitol_dh_C PF08125.13 CBZ27511.1 - 0.057 12.9 0.0 0.075 12.5 0.0 1.1 1 0 0 1 1 1 0 Mannitol dehydrogenase C-terminal domain adh_short PF00106.25 CBZ27512.1 - 1.6e-19 70.1 0.3 3.3e-19 69.1 0.1 1.6 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 CBZ27512.1 - 2e-10 40.6 0.1 4.4e-10 39.5 0.1 1.5 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CBZ27512.1 - 1.5e-07 31.5 0.1 3.1e-07 30.5 0.1 1.5 1 0 0 1 1 1 1 KR domain NAD_binding_7 PF13241.6 CBZ27512.1 - 0.018 15.5 0.0 0.035 14.6 0.0 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding Epimerase PF01370.21 CBZ27512.1 - 0.023 14.2 0.1 0.036 13.5 0.1 1.4 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family ApbA PF02558.16 CBZ27512.1 - 0.075 12.7 0.0 0.12 12.0 0.0 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA adh_short PF00106.25 CBZ27513.1 - 1.2e-22 80.3 0.0 1.8e-13 50.4 0.0 3.3 2 1 1 3 3 3 2 short chain dehydrogenase adh_short_C2 PF13561.6 CBZ27513.1 - 4.6e-11 42.7 0.0 1.5e-07 31.2 0.0 2.4 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CBZ27513.1 - 4.9e-06 26.6 0.0 1.4e-05 25.1 0.0 1.8 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 CBZ27513.1 - 0.015 14.8 0.0 0.036 13.5 0.0 1.6 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family NAD_binding_7 PF13241.6 CBZ27513.1 - 0.075 13.5 0.0 0.25 11.8 0.0 1.9 2 1 0 2 2 2 0 Putative NAD(P)-binding WVELL PF14043.6 CBZ27514.1 - 0.065 13.1 0.3 0.13 12.1 0.3 1.5 1 0 0 1 1 1 0 WVELL protein Abhydrolase_2 PF02230.16 CBZ27515.1 - 1.9e-37 129.2 0.0 2.5e-37 128.8 0.0 1.1 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Hydrolase_4 PF12146.8 CBZ27515.1 - 0.00041 19.7 0.2 0.077 12.2 0.0 2.9 2 1 1 3 3 3 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 CBZ27515.1 - 0.0048 17.5 0.2 0.007 17.0 0.2 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family FSH1 PF03959.13 CBZ27515.1 - 0.01 15.5 0.0 0.022 14.4 0.0 1.5 1 1 0 1 1 1 0 Serine hydrolase (FSH1) DLH PF01738.18 CBZ27515.1 - 0.011 15.3 0.0 0.015 14.8 0.0 1.2 1 0 0 1 1 1 0 Dienelactone hydrolase family SMG1_N PF17229.2 CBZ27515.1 - 0.057 14.1 0.0 0.18 12.6 0.0 1.8 1 0 0 1 1 1 0 Serine/threonine-protein kinase SMG1 N-terminal Abhydrolase_1 PF00561.20 CBZ27515.1 - 0.083 12.5 0.6 16 5.0 0.6 2.8 1 1 1 2 2 2 0 alpha/beta hydrolase fold SPRY PF00622.28 CBZ27518.1 - 0.024 14.7 0.0 0.06 13.5 0.0 1.6 1 0 0 1 1 1 0 SPRY domain Cyclin PF08613.11 CBZ27519.1 - 2.8e-16 60.3 0.0 5e-16 59.5 0.0 1.4 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 CBZ27519.1 - 1.5e-06 28.0 0.1 3e-06 27.0 0.1 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain baeRF_family10 PF18854.1 CBZ27519.1 - 0.094 13.0 0.1 0.21 11.8 0.1 1.5 1 0 0 1 1 1 0 Bacterial archaeo-eukaryotic release factor family 10 Cyclin PF08613.11 CBZ27520.1 - 1.8e-20 73.9 0.0 3.4e-20 73.0 0.0 1.3 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 CBZ27520.1 - 4.9e-06 26.3 0.1 7.7e-06 25.7 0.1 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain PFU PF09070.11 CBZ27521.1 - 6.7e-26 90.8 0.3 1.1e-25 90.1 0.3 1.3 1 0 0 1 1 1 1 PFU (PLAA family ubiquitin binding) WD40 PF00400.32 CBZ27521.1 - 8.8e-24 83.3 25.6 3.6e-05 24.4 0.1 7.5 7 0 0 7 7 7 6 WD domain, G-beta repeat PUL PF08324.11 CBZ27521.1 - 5e-07 29.2 3.1 9.5e-07 28.3 3.1 1.4 1 0 0 1 1 1 1 PUL domain PPTA PF01239.22 CBZ27522.1 - 0.00057 19.5 6.2 0.049 13.4 0.6 3.7 3 0 0 3 3 3 2 Protein prenyltransferase alpha subunit repeat DnaJ PF00226.31 CBZ27523.1 - 0.037 14.1 0.0 0.062 13.4 0.0 1.5 1 0 0 1 1 1 0 DnaJ domain DUF4574 PF15141.6 CBZ27524.1 - 0.0045 16.9 0.5 0.017 15.0 0.5 2.0 1 0 0 1 1 1 1 Ubiquinol-cytochrome-c reductase complex assembly factor 3 CEP63 PF17045.5 CBZ27524.1 - 0.076 12.9 22.5 0.029 14.3 4.6 2.4 2 0 0 2 2 2 0 Centrosomal protein of 63 kDa ADIP PF11559.8 CBZ27524.1 - 2.1 8.4 26.1 0.48 10.5 6.1 3.2 3 0 0 3 3 3 0 Afadin- and alpha -actinin-Binding YabA PF06156.13 CBZ27524.1 - 4.1 8.1 15.9 8.2 7.1 4.4 3.6 3 1 1 4 4 4 0 Initiation control protein YabA UPF0242 PF06785.11 CBZ27524.1 - 7.4 6.6 23.3 3.2 7.8 3.6 2.7 2 1 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Ins134_P3_kin PF05770.11 CBZ27525.1 - 6.6e-06 25.8 0.1 0.01 15.4 0.1 3.3 3 0 0 3 3 3 3 Inositol 1,3,4-trisphosphate 5/6-kinase ATP-grasp domain Cnn_1N PF07989.11 CBZ27528.1 - 0.0047 17.1 3.3 0.0047 17.1 3.3 4.0 4 2 0 4 4 4 1 Centrosomin N-terminal motif 1 Seryl_tRNA_N PF02403.22 CBZ27528.1 - 0.054 13.7 19.9 0.046 14.0 1.1 3.6 2 2 1 3 3 3 0 Seryl-tRNA synthetase N-terminal domain TruB_C PF09142.11 CBZ27530.1 - 0.13 12.1 0.1 0.43 10.4 0.0 1.9 2 0 0 2 2 2 0 tRNA Pseudouridine synthase II, C terminal STOP PF05217.12 CBZ27530.1 - 0.37 11.1 12.3 0.26 11.6 9.6 2.3 2 1 0 2 2 2 0 STOP protein Pdase_M17_N2 PF18295.1 CBZ27531.1 - 0.066 13.5 2.9 0.18 12.1 2.9 1.7 1 0 0 1 1 1 0 M17 aminopeptidase N-terminal domain 2 PCIF1_WW PF12237.8 CBZ27532.1 - 3.8e-12 46.2 0.0 1e-11 44.8 0.0 1.7 1 1 0 1 1 1 1 Phosphorylated CTD interacting factor 1 WW domain PI3_PI4_kinase PF00454.27 CBZ27533.1 - 1.5e-43 149.4 0.0 3.1e-28 99.3 0.0 2.3 1 1 1 2 2 2 2 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.20 CBZ27533.1 - 2.1e-22 79.5 0.0 4.2e-22 78.5 0.0 1.4 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3K_C2 PF00792.24 CBZ27533.1 - 0.00081 19.3 0.0 0.0014 18.5 0.0 1.4 1 0 0 1 1 1 1 Phosphoinositide 3-kinase C2 DUF4135 PF13575.6 CBZ27533.1 - 0.02 14.2 0.0 0.032 13.5 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4135) TFCD_C PF12612.8 CBZ27534.1 - 6.4e-31 107.7 0.0 2.6e-30 105.7 0.0 2.1 1 0 0 1 1 1 1 Tubulin folding cofactor D C terminal HEAT_2 PF13646.6 CBZ27534.1 - 3.5e-07 30.5 24.2 0.0022 18.3 0.6 7.5 8 1 0 8 8 8 4 HEAT repeats Cnd1 PF12717.7 CBZ27534.1 - 2.4e-05 24.4 1.4 0.29 11.2 0.1 4.7 5 0 0 5 5 5 2 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 CBZ27534.1 - 0.00033 20.7 33.0 0.92 9.9 0.0 11.0 11 1 1 12 12 12 3 HEAT repeat adh_short_C2 PF13561.6 CBZ27535.1 - 9.5e-44 149.7 0.3 1.3e-43 149.3 0.3 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 CBZ27535.1 - 2.4e-43 147.9 1.4 3.1e-43 147.5 1.4 1.0 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 CBZ27535.1 - 7e-10 39.1 3.6 3.4e-09 36.9 3.6 1.9 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 CBZ27535.1 - 1.2e-05 25.0 0.7 4.2e-05 23.1 0.7 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family AlaDh_PNT_C PF01262.21 CBZ27535.1 - 6.8e-05 22.3 0.2 0.00013 21.4 0.2 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain DUF2235 PF09994.9 CBZ27535.1 - 0.035 13.5 0.0 0.043 13.2 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized alpha/beta hydrolase domain (DUF2235) NAD_binding_10 PF13460.6 CBZ27535.1 - 0.056 13.3 1.4 0.069 13.0 1.3 1.4 1 1 0 1 1 1 0 NAD(P)H-binding THF_DHG_CYH_C PF02882.19 CBZ27535.1 - 0.06 12.7 0.0 0.11 11.8 0.0 1.4 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain 3HCDH_N PF02737.18 CBZ27535.1 - 0.072 13.0 0.3 0.12 12.2 0.3 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_8 PF13450.6 CBZ27535.1 - 0.074 13.3 0.1 0.16 12.2 0.1 1.5 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain 2-Hacid_dh_C PF02826.19 CBZ27535.1 - 0.077 12.3 0.3 0.15 11.4 0.1 1.6 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain BolA PF01722.18 CBZ27536.1 - 1.4e-14 54.1 0.0 1.7e-14 53.9 0.0 1.2 1 0 0 1 1 1 1 BolA-like protein Ribosomal_L26 PF16906.5 CBZ27538.1 - 3.1e-37 126.9 1.6 3.9e-37 126.6 1.6 1.1 1 0 0 1 1 1 1 Ribosomal proteins L26 eukaryotic, L24P archaeal KOW PF00467.29 CBZ27538.1 - 1.2e-06 28.3 1.1 3e-06 27.0 1.1 1.8 1 1 0 1 1 1 1 KOW motif Transketolase_N PF00456.21 CBZ27539.1 - 6.1e-140 465.9 0.1 8e-140 465.5 0.1 1.1 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.24 CBZ27539.1 - 2.5e-42 144.6 0.0 4e-42 143.9 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 CBZ27539.1 - 1.8e-08 34.3 0.1 4.5e-08 33.0 0.1 1.7 1 0 0 1 1 1 1 Transketolase, C-terminal domain DXP_synthase_N PF13292.6 CBZ27539.1 - 0.00071 18.9 0.0 0.0013 18.0 0.0 1.5 1 1 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase TPP_enzyme_C PF02775.21 CBZ27539.1 - 0.0011 18.7 0.8 0.0045 16.8 0.1 2.4 2 1 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain E1_dh PF00676.20 CBZ27539.1 - 0.0065 15.5 0.1 0.011 14.8 0.1 1.3 1 0 0 1 1 1 1 Dehydrogenase E1 component Terpene_synth PF01397.21 CBZ27539.1 - 0.043 13.5 0.1 0.1 12.3 0.0 1.6 2 0 0 2 2 2 0 Terpene synthase, N-terminal domain Ribosomal_S8e PF01201.22 CBZ27540.1 - 1.1e-46 158.4 2.0 1.3e-46 158.2 2.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S8e Ribosomal_S8e PF01201.22 CBZ27541.1 - 1.1e-46 158.4 2.0 1.3e-46 158.2 2.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S8e Kelch_3 PF13415.6 CBZ27542.1 - 5.9e-40 134.8 4.7 2.4e-09 37.2 0.0 7.3 7 0 0 7 7 7 6 Galactose oxidase, central domain Kelch_1 PF01344.25 CBZ27542.1 - 9.2e-35 118.0 21.8 3.8e-08 32.8 0.0 6.4 6 0 0 6 6 6 6 Kelch motif Kelch_4 PF13418.6 CBZ27542.1 - 1.7e-34 117.6 18.0 2.1e-06 27.7 0.1 6.9 5 1 1 6 6 6 6 Galactose oxidase, central domain Kelch_5 PF13854.6 CBZ27542.1 - 8.1e-31 105.5 16.5 2e-07 30.8 0.5 6.3 6 0 0 6 6 6 6 Kelch motif Kelch_6 PF13964.6 CBZ27542.1 - 1.5e-28 98.1 11.2 2.4e-07 30.8 0.0 6.5 5 1 1 6 6 6 5 Kelch motif Kelch_2 PF07646.15 CBZ27542.1 - 9e-26 88.8 16.7 1.9e-06 27.6 0.4 6.6 6 1 0 6 6 6 6 Kelch motif HMG_CoA_synt_N PF01154.17 CBZ27544.1 - 9.9e-12 45.1 0.1 1.8e-11 44.2 0.1 1.4 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal HMG_CoA_synt_C PF08540.10 CBZ27544.1 - 1.2e-06 28.4 0.3 0.00037 20.2 0.0 2.7 3 0 0 3 3 3 2 Hydroxymethylglutaryl-coenzyme A synthase C terminal ACP_syn_III PF08545.10 CBZ27544.1 - 0.00026 20.8 0.6 0.00072 19.4 0.1 2.0 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III UQ_con PF00179.26 CBZ27546.1 - 1.5e-44 151.1 0.1 1.6e-44 150.9 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 CBZ27546.1 - 0.00084 19.6 0.3 0.0015 18.8 0.2 1.4 1 1 0 1 1 1 1 RWD domain UEV PF05743.13 CBZ27546.1 - 0.001 18.9 0.3 0.0018 18.2 0.3 1.4 1 1 0 1 1 1 1 UEV domain Prok-E2_B PF14461.6 CBZ27546.1 - 0.0038 16.9 0.0 0.0047 16.6 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B UQ_con PF00179.26 CBZ27547.1 - 2.3e-07 30.6 0.1 4e-07 29.8 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 CBZ27547.1 - 0.043 14.1 0.0 0.06 13.6 0.0 1.3 1 0 0 1 1 1 0 RWD domain GDPD PF03009.17 CBZ27549.1 - 2.1e-20 73.5 0.0 2.9e-20 73.1 0.0 1.2 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family Vps54_N PF10475.9 CBZ27550.1 - 6.9e-13 48.5 0.6 1.8e-12 47.2 0.6 1.7 1 0 0 1 1 1 1 Vacuolar-sorting protein 54, of GARP complex DUF2451 PF10474.9 CBZ27550.1 - 6.3e-11 42.5 2.3 6.7e-11 42.4 1.1 1.7 2 0 0 2 2 2 1 Protein of unknown function C-terminus (DUF2451) Sec8_exocyst PF04048.14 CBZ27550.1 - 0.0011 18.8 0.4 0.0027 17.6 0.4 1.6 1 0 0 1 1 1 1 Sec8 exocyst complex component specific domain PPR_3 PF13812.6 CBZ27553.1 - 7.9e-13 48.3 0.0 3.4e-05 23.8 0.0 3.1 1 1 3 4 4 4 3 Pentatricopeptide repeat domain PPR_long PF17177.4 CBZ27553.1 - 4e-07 29.6 0.1 8.1e-07 28.6 0.1 1.4 1 1 0 1 1 1 1 Pentacotripeptide-repeat region of PRORP PPR_2 PF13041.6 CBZ27553.1 - 1.8e-06 28.1 0.0 0.0024 18.0 0.0 2.9 2 1 1 3 3 3 3 PPR repeat family PPR PF01535.20 CBZ27553.1 - 0.0015 18.6 0.0 2.8 8.4 0.0 3.8 4 0 0 4 4 4 1 PPR repeat Ribosomal_L11_N PF03946.14 CBZ27554.1 - 1.1e-16 60.4 0.5 1.8e-16 59.7 0.5 1.4 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.19 CBZ27554.1 - 7.5e-14 52.0 1.8 8.2e-14 51.9 0.6 1.7 2 0 0 2 2 2 1 Ribosomal protein L11, RNA binding domain AAA_5 PF07728.14 CBZ27555.1 - 0.091 12.8 0.0 0.31 11.0 0.0 1.8 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA PF00004.29 CBZ27555.1 - 0.16 12.4 0.0 0.36 11.3 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Torsin PF06309.11 CBZ27555.1 - 0.19 11.9 0.0 0.35 11.0 0.0 1.4 1 0 0 1 1 1 0 Torsin DUF2070 PF09843.9 CBZ27556.1 - 0.49 8.6 2.4 0.51 8.6 2.4 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) DUF5345 PF17280.2 CBZ27556.1 - 1.2 9.2 7.8 0.35 10.9 2.9 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5345) Wzz PF02706.15 CBZ27556.1 - 3.8 7.9 6.5 2.1 8.7 0.7 2.4 1 1 1 2 2 2 0 Chain length determinant protein Cob_adeno_trans PF01923.18 CBZ27557.1 - 8.3e-51 172.4 0.5 1.2e-50 171.9 0.5 1.2 1 0 0 1 1 1 1 Cobalamin adenosyltransferase DUF5522 PF17653.1 CBZ27557.1 - 1.7e-20 72.7 1.2 1.7e-20 72.7 1.2 1.9 2 0 0 2 2 2 1 Family of unknown function (DUF5522) FA_desaturase PF00487.24 CBZ27558.1 - 1e-18 68.2 19.8 1e-18 68.2 19.8 1.4 1 1 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.28 CBZ27558.1 - 1.5e-08 34.6 0.7 6.5e-07 29.4 0.0 3.4 5 0 0 5 5 5 1 Cytochrome b5-like Heme/Steroid binding domain TssN PF17555.2 CBZ27558.1 - 0.09 12.1 0.1 0.09 12.1 0.1 2.2 2 0 0 2 2 2 0 Type VI secretion system, TssN WD40 PF00400.32 CBZ27559.1 - 1.1e-53 178.0 30.3 4.7e-08 33.6 0.0 8.9 8 1 0 8 8 8 8 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBZ27559.1 - 2.4e-21 75.8 5.2 0.00038 20.7 0.0 6.5 2 2 4 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain NLE PF08154.12 CBZ27559.1 - 5.8e-13 49.2 0.1 9.6e-13 48.5 0.1 1.4 1 0 0 1 1 1 1 NLE (NUC135) domain Ge1_WD40 PF16529.5 CBZ27559.1 - 1.6e-08 33.9 0.3 0.045 12.7 0.0 4.5 2 2 3 5 5 5 3 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 CBZ27559.1 - 6.3e-07 29.5 0.0 0.039 13.8 0.0 2.6 2 0 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 CBZ27559.1 - 1e-06 28.3 0.0 0.28 10.5 0.0 3.3 2 1 1 3 3 3 3 WD40-like domain PD40 PF07676.12 CBZ27559.1 - 2.8e-05 23.9 3.1 1.9 8.5 0.1 4.9 5 0 0 5 5 5 2 WD40-like Beta Propeller Repeat Nbas_N PF15492.6 CBZ27559.1 - 0.00046 19.6 0.7 0.23 10.8 0.0 3.7 3 1 1 4 4 4 1 Neuroblastoma-amplified sequence, N terminal DHHC PF01529.20 CBZ27560.1 - 1.5e-13 51.0 12.3 1.5e-13 51.0 12.3 3.1 2 2 0 2 2 2 1 DHHC palmitoyltransferase DEAD_2 PF06733.15 CBZ27561.1 - 2.6e-39 134.7 0.0 7e-39 133.3 0.0 1.7 1 0 0 1 1 1 1 DEAD_2 Helicase_C_2 PF13307.6 CBZ27561.1 - 2.8e-39 135.0 0.0 5.9e-39 134.0 0.0 1.6 1 0 0 1 1 1 1 Helicase C-terminal domain HBB PF06777.11 CBZ27561.1 - 1.2e-35 123.0 1.5 3.5e-30 105.1 0.4 2.5 2 0 0 2 2 2 2 Helical and beta-bridge domain DEAD PF00270.29 CBZ27561.1 - 0.00025 20.9 0.6 0.016 14.9 0.0 2.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.15 CBZ27561.1 - 0.00029 20.9 0.2 0.0032 17.5 0.0 2.3 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 CBZ27561.1 - 0.015 15.7 0.0 0.045 14.1 0.0 1.8 1 1 0 1 1 1 0 AAA domain Glyco_transf_21 PF13506.6 CBZ27561.1 - 0.017 14.6 0.1 0.18 11.3 0.0 2.5 2 0 0 2 2 2 0 Glycosyl transferase family 21 Flavi_DEAD PF07652.14 CBZ27561.1 - 0.029 14.3 0.4 1.2 9.1 0.0 2.5 2 0 0 2 2 2 0 Flavivirus DEAD domain SAPIS-gp6 PF16722.5 CBZ27561.1 - 0.031 14.7 0.7 0.067 13.6 0.7 1.5 1 0 0 1 1 1 0 Pathogenicity island protein gp6 in Staphylococcus AAA_22 PF13401.6 CBZ27561.1 - 0.045 14.0 1.5 0.44 10.8 0.0 3.2 3 1 0 3 3 3 0 AAA domain Cullin PF00888.22 CBZ27562.1 - 3.7e-79 267.0 0.0 5e-79 266.6 0.0 1.1 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 CBZ27562.1 - 2.3e-23 82.0 0.2 6.2e-23 80.6 0.2 1.8 1 0 0 1 1 1 1 Cullin protein neddylation domain Vac_Fusion PF02346.16 CBZ27563.1 - 0.016 14.8 0.2 0.78 9.4 0.1 2.5 2 1 0 2 2 2 0 Chordopoxvirus multifunctional envelope protein A27 HIP1_clath_bdg PF16515.5 CBZ27564.1 - 0.025 15.2 2.6 0.025 15.2 2.6 2.3 2 1 0 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 TMEM89 PF15098.6 CBZ27564.1 - 0.063 13.4 0.2 0.095 12.9 0.1 1.3 1 1 0 1 1 1 0 TMEM89 protein family DUF4201 PF13870.6 CBZ27564.1 - 0.073 12.8 13.7 0.52 10.0 3.0 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4201) DUF4407 PF14362.6 CBZ27564.1 - 0.19 11.0 8.7 0.23 10.8 8.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) ABC_tran_CTD PF16326.5 CBZ27564.1 - 0.46 10.8 16.0 1.7 9.0 0.1 3.4 3 1 0 3 3 3 0 ABC transporter C-terminal domain UPF0242 PF06785.11 CBZ27564.1 - 0.63 10.1 14.2 0.32 11.1 4.8 2.1 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus FlgN PF05130.12 CBZ27564.1 - 1 9.9 12.4 1 9.9 9.7 1.9 1 1 1 2 2 2 0 FlgN protein Tup_N PF08581.10 CBZ27564.1 - 1.8 8.9 10.7 0.23 11.8 1.2 3.1 2 1 1 3 3 3 0 Tup N-terminal FlxA PF14282.6 CBZ27564.1 - 2.2 8.3 7.1 0.39 10.7 1.1 2.2 2 1 0 2 2 2 0 FlxA-like protein DivIC PF04977.15 CBZ27564.1 - 2.2 8.1 19.8 1.8 8.4 0.3 3.9 2 2 2 4 4 4 0 Septum formation initiator KxDL PF10241.9 CBZ27564.1 - 2.6 8.4 8.7 1.3 9.4 1.8 2.6 2 2 0 2 2 2 0 Uncharacterized conserved protein APG6_N PF17675.1 CBZ27564.1 - 3.1 8.4 19.6 5.7 7.5 7.9 2.3 2 0 0 2 2 2 0 Apg6 coiled-coil region ADIP PF11559.8 CBZ27564.1 - 3.1 7.9 12.3 36 4.4 8.5 2.2 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding DASH_Dad2 PF08654.10 CBZ27564.1 - 3.3 8.2 9.2 0.8 10.2 0.2 3.3 3 1 0 3 3 3 0 DASH complex subunit Dad2 Pkinase PF00069.25 CBZ27565.1 - 9.7e-61 205.4 0.0 1.1e-60 205.2 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ27565.1 - 3.6e-39 134.6 0.0 4.7e-39 134.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CBZ27565.1 - 0.0011 18.4 0.0 0.0033 16.8 0.0 1.7 1 1 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 CBZ27565.1 - 0.018 13.8 0.0 0.029 13.2 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase FTA2 PF13095.6 CBZ27565.1 - 0.026 14.2 0.1 0.89 9.1 0.0 2.2 1 1 1 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Methyltransf_33 PF10017.9 CBZ27565.1 - 0.032 13.4 0.0 0.049 12.8 0.0 1.2 1 0 0 1 1 1 0 Histidine-specific methyltransferase, SAM-dependent GLTSCR1 PF15249.6 CBZ27566.1 - 0.017 15.6 1.3 0.017 15.6 1.3 2.9 3 0 0 3 3 3 0 Conserved region of unknown function on GLTSCR protein Caldesmon PF02029.15 CBZ27566.1 - 0.25 10.1 30.4 0.3 9.8 30.4 1.1 1 0 0 1 1 1 0 Caldesmon GAGA_bind PF06217.12 CBZ27566.1 - 3.2 7.9 11.3 4.1 7.6 11.3 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family SpoU_methylase PF00588.19 CBZ27567.1 - 7.5e-15 55.3 0.1 4.4e-08 33.4 0.0 2.4 2 0 0 2 2 2 2 SpoU rRNA Methylase family Glycos_transf_2 PF00535.26 CBZ27568.1 - 2.7e-07 30.5 0.1 8.5e-07 28.9 0.0 1.8 2 0 0 2 2 2 1 Glycosyl transferase family 2 FR47 PF08445.10 CBZ27569.1 - 4.9e-07 29.6 0.1 7.6e-07 29.0 0.1 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.7 CBZ27569.1 - 4.6e-06 26.6 0.1 6.3e-06 26.2 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 CBZ27569.1 - 3.4e-05 24.1 0.0 5.1e-05 23.5 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Wzt_C PF14524.6 CBZ27569.1 - 0.14 12.2 0.0 0.24 11.4 0.0 1.3 1 0 0 1 1 1 0 Wzt C-terminal domain DUF2431 PF10354.9 CBZ27570.1 - 5e-26 91.9 0.0 7.9e-26 91.3 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF2431) zf-C2H2 PF00096.26 CBZ27570.1 - 0.0022 18.3 16.9 0.32 11.5 1.1 4.2 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CBZ27570.1 - 0.0032 18.2 12.5 4 8.5 0.2 4.4 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 CBZ27570.1 - 0.0034 17.6 3.8 0.22 11.9 0.1 3.5 3 0 0 3 3 3 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 CBZ27570.1 - 0.055 13.9 0.1 0.055 13.9 0.1 3.1 3 1 0 3 3 3 0 Zinc-finger of C2H2 type zf-C2H2_3 PF13878.6 CBZ27570.1 - 2.2 8.2 5.5 0.61 9.9 0.1 2.5 2 0 0 2 2 2 0 zinc-finger of acetyl-transferase ESCO YabA PF06156.13 CBZ27571.1 - 0.12 13.1 0.2 0.12 13.1 0.2 3.7 4 1 1 5 5 5 0 Initiation control protein YabA TSC22 PF01166.18 CBZ27571.1 - 0.77 10.1 3.2 1 9.7 0.3 2.7 2 0 0 2 2 2 0 TSC-22/dip/bun family CEP44 PF15007.6 CBZ27572.1 - 0.00017 21.7 0.0 0.0002 21.5 0.0 1.1 1 0 0 1 1 1 1 Centrosomal spindle body, CEP44 Got1 PF04178.12 CBZ27573.1 - 3.5e-27 95.1 15.2 4.4e-27 94.7 15.2 1.2 1 0 0 1 1 1 1 Got1/Sft2-like family AzlD PF05437.12 CBZ27573.1 - 0.085 13.0 6.8 0.17 12.1 6.8 1.5 1 1 0 1 1 1 0 Branched-chain amino acid transport protein (AzlD) DUF3270 PF11674.8 CBZ27573.1 - 0.47 10.7 4.7 0.26 11.5 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3270) DUF2070 PF09843.9 CBZ27573.1 - 3.6 5.7 7.7 4.4 5.5 7.7 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) RRM_1 PF00076.22 CBZ27575.1 - 3.1e-65 215.9 0.4 1.4e-18 66.5 0.0 4.3 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP PF00658.18 CBZ27575.1 - 2.1e-18 66.3 0.2 4.1e-18 65.3 0.2 1.5 1 0 0 1 1 1 1 Poly-adenylate binding protein, unique domain RRM_occluded PF16842.5 CBZ27575.1 - 1.1e-10 41.2 0.0 0.00026 20.8 0.0 4.1 4 0 0 4 4 4 2 Occluded RNA-recognition motif RRM_7 PF16367.5 CBZ27575.1 - 3.2e-06 27.2 0.1 0.12 12.5 0.0 4.8 4 2 0 4 4 4 1 RNA recognition motif DUF4523 PF15023.6 CBZ27575.1 - 0.0026 17.6 0.4 0.14 12.0 0.0 3.0 1 1 2 3 3 3 1 Protein of unknown function (DUF4523) DUF4485 PF14846.6 CBZ27575.1 - 0.034 14.2 0.1 6.7 6.8 0.0 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4485) Nup35_RRM_2 PF14605.6 CBZ27575.1 - 0.15 12.1 0.0 19 5.3 0.0 3.3 3 0 0 3 3 3 0 Nup53/35/40-type RNA recognition motif RPAP1_N PF08621.10 CBZ27576.1 - 0.0076 16.0 1.4 1.4 8.7 0.2 2.2 2 0 0 2 2 2 2 RPAP1-like, N-terminal Spidroin_N PF16763.5 CBZ27576.1 - 0.063 13.3 0.2 0.077 13.0 0.2 1.1 1 0 0 1 1 1 0 Major ampullate spidroin 1, spider silk protein 1, N-term Ketoacyl-synt_C PF02801.22 CBZ27576.1 - 0.11 12.6 0.3 0.53 10.3 0.0 1.9 1 1 1 2 2 2 0 Beta-ketoacyl synthase, C-terminal domain RAMP4 PF06624.12 CBZ27577.1 - 0.0039 17.2 0.0 0.0044 17.0 0.0 1.1 1 0 0 1 1 1 1 Ribosome associated membrane protein RAMP4 CrgA PF06781.12 CBZ27577.1 - 0.0064 16.5 0.2 0.0065 16.5 0.2 1.1 1 0 0 1 1 1 1 Cell division protein CrgA ETF PF01012.21 CBZ27579.1 - 2.2e-43 148.2 2.5 2.8e-43 147.9 2.5 1.1 1 0 0 1 1 1 1 Electron transfer flavoprotein domain PIG-L PF02585.17 CBZ27579.1 - 0.021 15.4 0.0 0.05 14.2 0.0 1.6 1 0 0 1 1 1 0 GlcNAc-PI de-N-acetylase GTP_EFTU PF00009.27 CBZ27580.1 - 7.4e-50 169.2 0.2 1.2e-49 168.6 0.2 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.24 CBZ27580.1 - 8.3e-14 51.4 0.0 2e-13 50.2 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus Septin PF00735.18 CBZ27580.1 - 1.5e-05 24.5 0.1 2.4e-05 23.8 0.1 1.2 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.23 CBZ27580.1 - 2.4e-05 24.4 0.1 5.3e-05 23.3 0.1 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D2 PF03144.25 CBZ27580.1 - 0.0045 17.3 0.0 0.02 15.2 0.0 2.1 2 0 0 2 2 2 1 Elongation factor Tu domain 2 EFG_II PF14492.6 CBZ27580.1 - 0.031 14.4 0.7 0.075 13.1 0.0 2.0 2 0 0 2 2 2 0 Elongation Factor G, domain II RNA_pol_Rpb6 PF01192.22 CBZ27581.1 - 4.1e-08 33.0 0.0 6.2e-08 32.4 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb6 GIT_CC PF16559.5 CBZ27583.1 - 0.03 14.2 0.1 0.1 12.4 0.1 1.9 1 0 0 1 1 1 0 GIT coiled-coil Rho guanine nucleotide exchange factor BSD PF03909.17 CBZ27583.1 - 0.051 13.6 0.0 0.31 11.1 0.0 2.1 2 0 0 2 2 2 0 BSD domain NUP50 PF08911.11 CBZ27583.1 - 0.054 14.2 0.3 0.13 13.0 0.3 1.6 1 0 0 1 1 1 0 NUP50 (Nucleoporin 50 kDa) SAE2 PF08573.10 CBZ27583.1 - 0.18 12.9 1.3 5.1 8.3 0.1 2.2 2 0 0 2 2 2 0 DNA repair protein endonuclease SAE2/CtIP C-terminus TPR_MLP1_2 PF07926.12 CBZ27583.1 - 0.19 11.8 10.1 0.038 14.0 4.5 2.1 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein DivIC PF04977.15 CBZ27583.1 - 3.8 7.3 7.4 0.72 9.7 0.4 2.5 2 1 0 2 2 2 0 Septum formation initiator Lactamase_B_6 PF16661.5 CBZ27584.1 - 1e-18 67.5 0.0 1.6e-18 66.8 0.0 1.3 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily domain CPSF100_C PF13299.6 CBZ27584.1 - 9.5e-15 55.2 4.4 1.1e-14 54.9 0.2 2.8 2 1 0 2 2 2 1 Cleavage and polyadenylation factor 2 C-terminal Lactamase_B_2 PF12706.7 CBZ27584.1 - 0.00067 19.2 0.1 0.002 17.7 0.0 1.9 2 1 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 CBZ27584.1 - 0.027 14.5 0.1 0.066 13.2 0.1 1.7 1 0 0 1 1 1 0 Metallo-beta-lactamase superfamily Rotamase_2 PF13145.6 CBZ27584.1 - 0.11 13.3 3.1 0.27 12.1 3.1 1.6 1 0 0 1 1 1 0 PPIC-type PPIASE domain Peptidase_C12 PF01088.21 CBZ27586.1 - 1.5e-54 184.9 0.0 1.7e-54 184.8 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 DTW PF03942.15 CBZ27586.1 - 0.024 14.4 0.0 0.027 14.2 0.0 1.2 1 0 0 1 1 1 0 DTW domain WD40_3 PF15911.5 CBZ27587.1 - 7.7e-16 57.9 0.1 6.6e-14 51.6 0.0 2.9 1 1 1 2 2 2 1 WD domain, G-beta repeat Clathrin PF00637.20 CBZ27587.1 - 6.8e-07 29.2 7.2 0.00068 19.5 0.3 4.6 5 0 0 5 5 5 2 Region in Clathrin and VPS ANAPC4_WD40 PF12894.7 CBZ27587.1 - 0.00085 19.6 0.0 0.8 10.1 0.0 3.8 2 2 2 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain zf-ribbon_3 PF13248.6 CBZ27587.1 - 0.02 14.3 8.7 0.57 9.7 0.5 2.7 2 0 0 2 2 2 0 zinc-ribbon domain TPR_19 PF14559.6 CBZ27587.1 - 0.038 14.5 9.8 0.37 11.3 0.1 5.4 5 0 0 5 5 5 0 Tetratricopeptide repeat GGA_N-GAT PF18308.1 CBZ27587.1 - 0.15 11.7 0.2 0.54 9.9 0.0 2.0 2 0 0 2 2 2 0 GGA N-GAT domain TPR_12 PF13424.6 CBZ27587.1 - 4.8 7.5 18.3 29 5.0 1.0 6.6 6 1 1 7 7 7 0 Tetratricopeptide repeat DZR PF12773.7 CBZ27587.1 - 5.4 7.1 8.7 76 3.4 8.8 2.6 1 1 0 1 1 1 0 Double zinc ribbon TPR_7 PF13176.6 CBZ27587.1 - 9.4 6.5 11.5 6.4 7.0 0.5 5.7 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_14 PF13428.6 CBZ27587.1 - 9.5 7.4 16.1 38 5.5 0.3 6.1 7 0 0 7 7 7 0 Tetratricopeptide repeat Mito_carr PF00153.27 CBZ27588.1 - 5.8e-60 199.2 0.2 2.3e-19 69.1 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein SyrA PF11089.8 CBZ27589.1 - 0.054 13.6 2.1 0.099 12.7 2.1 1.4 1 0 0 1 1 1 0 Exopolysaccharide production repressor TMEM237 PF15383.6 CBZ27589.1 - 0.17 10.9 0.2 0.3 10.1 0.2 1.4 1 0 0 1 1 1 0 Transmembrane protein 237 Spt5_N PF11942.8 CBZ27589.1 - 0.42 11.6 5.2 1.4 9.9 0.1 2.6 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal DSPc PF00782.20 CBZ27590.1 - 1.7e-16 60.3 0.1 2.7e-16 59.6 0.1 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain CDKN3 PF05706.12 CBZ27590.1 - 0.00012 21.8 0.0 0.0002 21.1 0.0 1.3 1 0 0 1 1 1 1 Cyclin-dependent kinase inhibitor 3 (CDKN3) Y_phosphatase3 PF13350.6 CBZ27590.1 - 0.002 18.1 0.1 0.0035 17.4 0.1 1.4 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase PF00102.27 CBZ27590.1 - 0.0039 16.8 0.3 0.0054 16.3 0.3 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 CBZ27590.1 - 0.0095 16.1 0.0 0.016 15.3 0.0 1.4 1 0 0 1 1 1 1 Inositol hexakisphosphate DUF442 PF04273.13 CBZ27590.1 - 0.0099 16.0 0.1 0.019 15.0 0.1 1.4 1 0 0 1 1 1 1 Putative phosphatase (DUF442) Y_phosphatase2 PF03162.13 CBZ27590.1 - 0.13 11.8 0.0 0.29 10.7 0.0 1.5 1 0 0 1 1 1 0 Tyrosine phosphatase family Bud13 PF09736.9 CBZ27591.1 - 7.5e-07 29.6 0.0 1.3e-06 28.9 0.0 1.4 1 0 0 1 1 1 1 Pre-mRNA-splicing factor of RES complex KxDL PF10241.9 CBZ27592.1 - 0.2 12.0 2.6 5.1 7.4 0.1 2.8 2 0 0 2 2 2 0 Uncharacterized conserved protein AAA_33 PF13671.6 CBZ27592.1 - 0.3 11.2 9.3 0.51 10.5 0.0 3.0 2 1 0 2 2 2 0 AAA domain SlyX PF04102.12 CBZ27592.1 - 0.85 10.3 8.9 0.62 10.7 1.6 3.5 2 1 0 2 2 2 0 SlyX ATG16 PF08614.11 CBZ27592.1 - 0.95 9.7 38.5 0.11 12.7 4.1 3.3 1 1 2 3 3 3 0 Autophagy protein 16 (ATG16) HALZ PF02183.18 CBZ27592.1 - 4.7 7.5 6.8 0.35 11.1 0.6 2.4 3 0 0 3 3 3 0 Homeobox associated leucine zipper Lectin_N PF03954.14 CBZ27592.1 - 5.3 6.8 6.8 1.7 8.4 0.2 3.0 3 0 0 3 3 3 0 Hepatic lectin, N-terminal domain Dynein_light PF01221.18 CBZ27593.1 - 1.7e-34 118.0 0.1 1.9e-34 117.8 0.1 1.0 1 0 0 1 1 1 1 Dynein light chain type 1 N_NLPC_P60 PF12912.7 CBZ27593.1 - 0.15 12.5 0.0 0.16 12.4 0.0 1.2 1 0 0 1 1 1 0 NLPC_P60 stabilising domain, N term YabA PF06156.13 CBZ27594.1 - 0.019 15.6 1.1 0.019 15.6 1.1 7.4 4 2 3 7 7 7 0 Initiation control protein YabA DUF4200 PF13863.6 CBZ27594.1 - 0.22 11.9 0.1 0.22 11.9 0.1 7.4 6 3 1 7 7 7 0 Domain of unknown function (DUF4200) CENP-F_leu_zip PF10473.9 CBZ27595.1 - 0.35 10.9 20.9 0.026 14.5 12.0 2.4 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Golgin_A5 PF09787.9 CBZ27595.1 - 0.52 9.7 16.9 0.015 14.8 7.8 2.5 3 0 0 3 3 3 0 Golgin subfamily A member 5 V_ATPase_I PF01496.19 CBZ27595.1 - 0.55 8.1 8.7 0.078 10.9 4.6 1.5 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family JIP_LZII PF16471.5 CBZ27595.1 - 0.63 10.3 6.7 1.6 8.9 5.3 2.4 1 1 0 1 1 1 0 JNK-interacting protein leucine zipper II Macoilin PF09726.9 CBZ27595.1 - 5.3 5.5 15.8 31 2.9 0.0 2.1 1 1 1 2 2 2 0 Macoilin family DUF1664 PF07889.12 CBZ27595.1 - 8.5 6.4 10.4 16 5.5 0.0 3.1 3 1 0 3 3 3 0 Protein of unknown function (DUF1664) RRM_1 PF00076.22 CBZ27596.1 - 6e-05 22.8 2.0 0.0014 18.4 0.0 2.6 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Diphthami_syn_2 PF01902.17 CBZ27597.1 - 6.4e-30 104.3 0.0 2.7e-24 85.9 0.0 2.8 2 1 0 2 2 2 2 Diphthamide synthase FTR PF01913.18 CBZ27598.1 - 0.012 15.5 0.2 0.013 15.4 0.2 1.1 1 0 0 1 1 1 0 Formylmethanofuran-tetrahydromethanopterin formyltransferase BRCT_2 PF16589.5 CBZ27599.1 - 3.8e-05 24.0 0.0 0.41 11.1 0.0 2.5 2 0 0 2 2 2 2 BRCT domain, a BRCA1 C-terminus domain LIG3_BRCT PF16759.5 CBZ27599.1 - 0.021 15.1 0.0 3.8 7.9 0.0 2.5 2 0 0 2 2 2 0 DNA ligase 3 BRCT domain B9-C2 PF07162.11 CBZ27600.1 - 3.9e-42 144.3 0.2 4.3e-42 144.2 0.2 1.0 1 0 0 1 1 1 1 Ciliary basal body-associated, B9 protein SPRY PF00622.28 CBZ27601.1 - 1.9e-06 28.0 0.0 3.8e-06 27.0 0.0 1.4 1 0 0 1 1 1 1 SPRY domain zf-RING_2 PF13639.6 CBZ27602.1 - 3.9e-08 33.5 11.3 1.1e-07 32.0 11.3 1.9 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 CBZ27602.1 - 2.1e-06 27.4 8.5 4.9e-06 26.2 8.5 1.7 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_5 PF14634.6 CBZ27602.1 - 0.00012 21.9 8.8 0.00012 21.9 8.8 1.9 2 0 0 2 2 2 1 zinc-RING finger domain zf-rbx1 PF12678.7 CBZ27602.1 - 0.00015 22.0 9.2 0.00044 20.5 9.2 1.8 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 CBZ27602.1 - 0.00029 20.8 4.8 0.00069 19.6 4.8 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4 PF00097.25 CBZ27602.1 - 0.0021 17.9 10.4 0.0052 16.6 10.4 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 CBZ27602.1 - 0.039 13.8 10.6 0.099 12.5 10.6 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CBZ27602.1 - 1.5 8.9 10.7 4.2 7.5 10.7 1.8 1 0 0 1 1 1 0 RING-type zinc-finger DUF1308 PF07000.11 CBZ27603.1 - 1.3e-20 74.0 0.0 8.5e-20 71.3 0.0 2.2 1 1 0 1 1 1 1 Protein of unknown function (DUF1308) zf_C2H2_13 PF18508.1 CBZ27604.1 - 0.15 11.7 0.2 0.24 11.0 0.2 1.3 1 0 0 1 1 1 0 Zinc finger domain Fcf2 PF08698.11 CBZ27605.1 - 5.5e-08 33.1 6.7 2.6e-07 30.9 6.7 2.2 1 1 0 1 1 1 1 Fcf2 pre-rRNA processing BetaGal_dom3 PF13363.6 CBZ27606.1 - 0.13 11.9 0.0 0.35 10.4 0.0 1.7 1 0 0 1 1 1 0 Beta-galactosidase, domain 3 CSN5_C PF18323.1 CBZ27606.1 - 4.6 8.2 10.9 6 7.8 3.1 3.9 3 0 0 3 3 3 0 Cop9 signalosome subunit 5 C-terminal domain SUI1 PF01253.22 CBZ27609.1 - 2e-18 66.7 0.8 4.9e-18 65.4 0.0 1.9 2 0 0 2 2 2 1 Translation initiation factor SUI1 SR-25 PF10500.9 CBZ27609.1 - 0.0044 16.7 2.5 0.0067 16.1 2.5 1.3 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein DUF4630 PF15443.6 CBZ27609.1 - 0.019 15.1 1.4 0.019 15.1 1.4 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4630) BRX_N PF13713.6 CBZ27610.1 - 0.0011 18.7 1.1 0.18 11.6 0.0 2.8 2 0 0 2 2 2 2 Transcription factor BRX N-terminal domain Pox_A_type_inc PF04508.12 CBZ27610.1 - 0.057 13.3 0.7 0.17 11.8 0.7 1.8 1 0 0 1 1 1 0 Viral A-type inclusion protein repeat BET PF17035.5 CBZ27610.1 - 0.28 11.4 1.1 1.1 9.5 1.1 2.0 1 0 0 1 1 1 0 Bromodomain extra-terminal - transcription regulation Baculo_PEP_C PF04513.12 CBZ27610.1 - 1.2 9.2 43.3 0.18 11.8 10.5 6.9 4 1 2 6 6 6 0 Baculovirus polyhedron envelope protein, PEP, C terminus UPF0184 PF03670.13 CBZ27610.1 - 1.8 9.0 7.6 15 6.0 0.4 3.5 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0184) WD40 PF00400.32 CBZ27611.1 - 4.1e-37 125.5 19.6 2.4e-08 34.5 0.9 8.9 9 0 0 9 9 9 6 WD domain, G-beta repeat Utp13 PF08625.11 CBZ27611.1 - 2.7e-34 118.1 1.5 4.8e-34 117.3 1.5 1.4 1 0 0 1 1 1 1 Utp13 specific WD40 associated domain ANAPC4_WD40 PF12894.7 CBZ27611.1 - 6.7e-16 58.4 6.7 1.1e-05 25.6 0.2 6.4 5 2 1 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 CBZ27611.1 - 1.8e-07 30.5 3.7 0.22 10.4 0.2 5.2 3 2 2 6 6 6 3 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 CBZ27611.1 - 0.00038 19.9 0.0 1.7 7.9 0.0 3.8 4 1 0 4 4 4 2 WD40-like domain MMS1_N PF10433.9 CBZ27611.1 - 0.01 14.5 0.1 0.1 11.2 0.0 2.6 3 0 0 3 3 3 0 Mono-functional DNA-alkylating methyl methanesulfonate N-term Utp12 PF04003.12 CBZ27611.1 - 0.062 13.6 0.9 0.13 12.6 0.9 1.6 1 0 0 1 1 1 0 Dip2/Utp12 Family Nup160 PF11715.8 CBZ27611.1 - 0.062 11.9 8.3 2.8 6.5 0.2 4.1 3 2 1 4 4 4 0 Nucleoporin Nup120/160 VID27 PF08553.10 CBZ27611.1 - 0.13 11.3 0.0 3.1 6.8 0.0 2.7 3 0 0 3 3 3 0 VID27 C-terminal WD40-like domain UTP15_C PF09384.10 CBZ27611.1 - 0.77 9.4 3.9 0.64 9.7 1.8 1.9 2 1 0 2 2 2 0 UTP15 C terminal TFIIB PF00382.19 CBZ27612.1 - 4.7e-23 81.0 0.1 1.5e-11 44.2 0.0 2.4 2 0 0 2 2 2 2 Transcription factor TFIIB repeat TF_Zn_Ribbon PF08271.12 CBZ27612.1 - 0.032 13.7 0.1 0.075 12.6 0.1 1.6 1 0 0 1 1 1 0 TFIIB zinc-binding MMR_HSR1 PF01926.23 CBZ27613.1 - 2e-13 50.4 0.0 3.5e-13 49.6 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 CBZ27613.1 - 7.8e-08 32.0 0.0 3.1e-06 26.8 0.0 2.1 2 0 0 2 2 2 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 CBZ27613.1 - 3.2e-06 27.2 0.0 2.3e-05 24.4 0.0 2.2 2 1 0 2 2 2 1 RsgA GTPase Dynamin_N PF00350.23 CBZ27613.1 - 0.0025 17.9 0.5 0.2 11.7 0.1 2.4 1 1 1 2 2 2 1 Dynamin family AIG1 PF04548.16 CBZ27613.1 - 0.0036 16.6 0.0 0.0062 15.9 0.0 1.3 1 0 0 1 1 1 1 AIG1 family GTP_EFTU PF00009.27 CBZ27613.1 - 0.004 16.7 0.1 0.41 10.1 0.1 2.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 CBZ27613.1 - 0.0052 16.2 0.0 0.0086 15.5 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Cyt_bd_oxida_II PF02322.15 CBZ27614.1 - 0.12 11.8 0.0 0.16 11.3 0.0 1.1 1 0 0 1 1 1 0 Cytochrome bd terminal oxidase subunit II Kringle PF00051.18 CBZ27615.1 - 3.2e-12 46.6 0.1 2e-11 44.0 0.1 2.2 2 0 0 2 2 2 1 Kringle domain CHB_HEX_C_1 PF13290.6 CBZ27615.1 - 0.085 12.9 7.6 0.086 12.9 0.1 4.2 2 1 1 3 3 3 0 Chitobiase/beta-hexosaminidase C-terminal domain Myosin_head PF00063.21 CBZ27616.1 - 0.016 13.4 0.0 0.03 12.5 0.0 1.3 1 0 0 1 1 1 0 Myosin head (motor domain) RRM_1 PF00076.22 CBZ27617.1 - 6.8e-22 77.1 0.0 9.2e-22 76.7 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 CBZ27617.1 - 0.00016 21.3 0.0 0.00025 20.6 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 CBZ27617.1 - 0.021 14.7 0.0 0.04 13.8 0.0 1.5 1 1 0 1 1 1 0 Occluded RNA-recognition motif Nup35_RRM_2 PF14605.6 CBZ27617.1 - 0.14 12.1 0.0 0.24 11.4 0.0 1.3 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif RCR PF12273.8 CBZ27617.1 - 2.7 8.7 19.3 0.04 14.6 3.1 2.3 2 0 0 2 2 2 0 Chitin synthesis regulation, resistance to Congo red RRM_1 PF00076.22 CBZ27618.1 - 6.3e-22 77.2 0.0 8.4e-22 76.8 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 CBZ27618.1 - 9.3e-05 22.0 0.0 0.00014 21.5 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 CBZ27618.1 - 0.019 14.8 0.0 0.036 13.9 0.0 1.5 1 1 0 1 1 1 0 Occluded RNA-recognition motif Nup35_RRM_2 PF14605.6 CBZ27618.1 - 0.13 12.3 0.0 0.22 11.6 0.0 1.4 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif ImcF-related_N PF14331.6 CBZ27619.1 - 0.0066 15.8 0.0 0.012 15.0 0.0 1.3 1 0 0 1 1 1 1 ImcF-related N-terminal domain RRM_1 PF00076.22 CBZ27620.1 - 7e-19 67.4 0.7 2e-18 65.9 0.1 2.0 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 CBZ27620.1 - 0.0051 16.4 0.0 0.0097 15.5 0.0 1.6 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) ABC_membrane PF00664.23 CBZ27621.1 - 3.1e-53 181.2 3.1 4.3e-53 180.7 3.1 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 CBZ27621.1 - 8.1e-33 113.8 0.0 1.5e-32 113.0 0.0 1.5 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 CBZ27621.1 - 2.6e-05 23.8 0.0 0.038 13.4 0.0 2.2 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 CBZ27621.1 - 0.00035 21.0 0.4 0.0024 18.3 0.4 2.3 1 1 0 1 1 1 1 AAA ATPase domain AAA PF00004.29 CBZ27621.1 - 0.0043 17.5 0.1 0.048 14.1 0.1 2.2 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DEAD PF00270.29 CBZ27621.1 - 0.0053 16.6 0.0 0.061 13.1 0.0 2.3 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_22 PF13401.6 CBZ27621.1 - 0.0086 16.3 0.4 0.26 11.6 0.0 2.6 2 1 1 3 3 3 1 AAA domain AAA_5 PF07728.14 CBZ27621.1 - 0.0093 16.0 0.0 0.22 11.5 0.0 2.7 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) AAA_29 PF13555.6 CBZ27621.1 - 0.022 14.5 0.0 0.054 13.2 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_ATPase PF09818.9 CBZ27621.1 - 0.026 13.3 0.1 0.05 12.4 0.1 1.4 1 0 0 1 1 1 0 Predicted ATPase of the ABC class Zeta_toxin PF06414.12 CBZ27621.1 - 0.031 13.6 0.0 0.069 12.4 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin RsgA_GTPase PF03193.16 CBZ27621.1 - 0.038 13.9 0.0 0.26 11.2 0.0 2.1 2 0 0 2 2 2 0 RsgA GTPase AAA_15 PF13175.6 CBZ27621.1 - 0.097 12.4 0.0 0.15 11.8 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain DUF3987 PF13148.6 CBZ27621.1 - 0.14 11.2 0.1 0.41 9.6 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3987) AAA_33 PF13671.6 CBZ27621.1 - 0.15 12.2 0.1 0.97 9.6 0.0 2.4 3 0 0 3 3 3 0 AAA domain DUF87 PF01935.17 CBZ27621.1 - 0.17 12.0 0.2 0.48 10.5 0.1 1.7 2 0 0 2 2 2 0 Helicase HerA, central domain SbcCD_C PF13558.6 CBZ27621.1 - 0.19 12.0 0.3 1.4 9.2 0.3 2.2 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit LSM14 PF12701.7 CBZ27622.1 - 2.1e-27 95.0 0.1 3.2e-27 94.4 0.1 1.3 1 0 0 1 1 1 1 Scd6-like Sm domain SM-ATX PF14438.6 CBZ27622.1 - 5.9e-06 26.3 0.1 1.1e-05 25.5 0.1 1.4 1 0 0 1 1 1 1 Ataxin 2 SM domain FDF PF09532.10 CBZ27622.1 - 0.00054 20.8 18.0 0.07 14.0 2.4 2.8 2 1 1 3 3 3 2 FDF domain DUF5578 PF17741.1 CBZ27623.1 - 1.8e-19 70.2 1.8 2.6e-08 33.6 0.2 3.3 3 0 0 3 3 3 3 Family of unknown function (DUF5578) DnaJ PF00226.31 CBZ27624.1 - 0.0011 19.0 0.1 0.0021 18.1 0.1 1.4 1 0 0 1 1 1 1 DnaJ domain Y_phosphatase2 PF03162.13 CBZ27625.1 - 1.7e-35 122.0 0.0 3.8e-27 94.9 0.0 2.1 2 0 0 2 2 2 2 Tyrosine phosphatase family Y_phosphatase3 PF13350.6 CBZ27625.1 - 0.00015 21.8 0.0 0.0002 21.4 0.0 1.2 1 0 0 1 1 1 1 Tyrosine phosphatase family Ins_beta PF03488.14 CBZ27626.1 - 0.094 12.7 0.0 0.19 11.8 0.0 1.4 1 0 0 1 1 1 0 Nematode insulin-related peptide beta type PreAtp-grasp PF18604.1 CBZ27626.1 - 0.15 11.7 0.0 0.21 11.2 0.0 1.2 1 0 0 1 1 1 0 Pre ATP-grasp domain DUF2475 PF10629.9 CBZ27628.1 - 0.045 13.9 0.7 0.12 12.6 0.7 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2475) Raptor_N PF14538.6 CBZ27629.1 - 1.6e-45 154.7 0.0 2.8e-45 153.9 0.0 1.4 1 0 0 1 1 1 1 Raptor N-terminal CASPase like domain HEAT PF02985.22 CBZ27629.1 - 4.2e-05 23.4 1.8 0.11 12.9 0.1 3.4 3 0 0 3 3 3 2 HEAT repeat HEAT_2 PF13646.6 CBZ27629.1 - 0.02 15.3 0.1 0.27 11.7 0.0 2.5 2 1 1 3 3 3 0 HEAT repeats Cnd1 PF12717.7 CBZ27629.1 - 0.15 12.1 0.0 0.46 10.5 0.0 1.8 1 0 0 1 1 1 0 non-SMC mitotic condensation complex subunit 1 NCOA_u2 PF16665.5 CBZ27629.1 - 2.8 8.3 8.5 0.25 11.7 0.8 2.5 2 0 0 2 2 2 0 Unstructured region on nuclear receptor coactivator protein RNA_pol_Rpb2_6 PF00562.28 CBZ27630.1 - 5.1e-73 246.4 0.0 3e-72 243.9 0.0 2.0 1 1 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_3 PF04565.16 CBZ27630.1 - 2.6e-19 69.2 0.0 8.2e-19 67.6 0.0 2.0 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_7 PF04560.20 CBZ27630.1 - 3e-14 53.2 0.0 7.1e-14 52.0 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpa2_4 PF06883.12 CBZ27630.1 - 3.7e-12 46.1 0.0 9.5e-12 44.7 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase I, Rpa2 specific domain RNA_pol_Rpb2_1 PF04563.15 CBZ27630.1 - 6.8e-08 32.3 0.0 2.4e-07 30.5 0.0 1.8 2 0 0 2 2 2 1 RNA polymerase beta subunit RNA_pol_Rpb2_4 PF04566.13 CBZ27630.1 - 0.048 13.9 0.0 0.18 12.1 0.0 2.0 1 0 0 1 1 1 0 RNA polymerase Rpb2, domain 4 zinc_ribbon_10 PF10058.9 CBZ27630.1 - 0.14 11.9 0.1 0.39 10.5 0.1 1.7 1 0 0 1 1 1 0 Predicted integral membrane zinc-ribbon metal-binding protein PPR PF01535.20 CBZ27631.1 - 0.00017 21.6 0.3 0.0015 18.6 0.0 2.5 2 0 0 2 2 2 1 PPR repeat PPR_2 PF13041.6 CBZ27631.1 - 0.0022 18.1 0.7 0.017 15.3 0.0 2.6 2 1 1 3 3 3 1 PPR repeat family PPR_3 PF13812.6 CBZ27631.1 - 0.0032 17.5 0.0 0.0083 16.2 0.0 1.7 1 0 0 1 1 1 1 Pentatricopeptide repeat domain PPR_1 PF12854.7 CBZ27631.1 - 0.0056 16.4 0.1 0.02 14.6 0.1 2.0 1 0 0 1 1 1 1 PPR repeat PPR_long PF17177.4 CBZ27631.1 - 0.026 13.9 0.1 0.036 13.4 0.1 1.2 1 0 0 1 1 1 0 Pentacotripeptide-repeat region of PRORP zf-AN1 PF01428.16 CBZ27633.1 - 5.2 7.3 30.5 2.9 8.1 11.3 2.5 2 0 0 2 2 2 0 AN1-like Zinc finger ENTH PF01417.20 CBZ27635.1 - 3.9e-27 94.8 0.0 6.1e-27 94.2 0.0 1.3 1 0 0 1 1 1 1 ENTH domain CCDC50_N PF15295.6 CBZ27635.1 - 0.4 10.8 18.3 1.2 9.3 18.3 1.8 1 1 0 1 1 1 0 Coiled-coil domain-containing protein 50 N-terminus NAD-GH PF10712.9 CBZ27635.1 - 0.56 8.6 2.3 0.82 8.0 2.3 1.1 1 0 0 1 1 1 0 NAD-specific glutamate dehydrogenase Alpha_kinase PF02816.18 CBZ27636.1 - 4.6e-55 186.6 0.0 7e-55 186.0 0.0 1.3 1 0 0 1 1 1 1 Alpha-kinase family SpoIID PF08486.10 CBZ27636.1 - 1 10.0 5.3 2.5 8.7 5.3 1.6 1 0 0 1 1 1 0 Stage II sporulation protein DAP10 PF07213.11 CBZ27636.1 - 2.4 8.2 4.8 0.83 9.7 0.1 2.6 2 0 0 2 2 2 0 DAP10 membrane protein SCAMP PF04144.13 CBZ27639.1 - 8.9e-34 117.3 9.6 1.1e-33 117.0 9.6 1.1 1 0 0 1 1 1 1 SCAMP family FtsL PF04999.13 CBZ27639.1 - 8.6 6.4 6.5 0.52 10.3 0.2 2.1 3 0 0 3 3 3 0 Cell division protein FtsL CitG PF01874.16 CBZ27640.1 - 0.13 11.9 0.1 0.18 11.4 0.1 1.1 1 0 0 1 1 1 0 ATP:dephospho-CoA triphosphoribosyl transferase eIF-5a PF01287.20 CBZ27641.1 - 1.5e-26 92.3 0.0 2.1e-26 91.8 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold EFP_N PF08207.12 CBZ27641.1 - 0.00021 21.2 0.0 0.00042 20.3 0.0 1.6 1 0 0 1 1 1 1 Elongation factor P (EF-P) KOW-like domain eIF-5a PF01287.20 CBZ27642.1 - 1.5e-26 92.3 0.0 2.1e-26 91.8 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold EFP_N PF08207.12 CBZ27642.1 - 0.00021 21.2 0.0 0.00042 20.3 0.0 1.6 1 0 0 1 1 1 1 Elongation factor P (EF-P) KOW-like domain SNF2_N PF00176.23 CBZ27643.1 - 5.2e-54 183.3 1.6 6.8e-28 97.4 0.0 3.5 2 2 0 2 2 2 2 SNF2 family N-terminal domain Helicase_C PF00271.31 CBZ27643.1 - 1.3e-17 64.2 0.1 6.1e-17 62.0 0.0 2.3 3 0 0 3 3 2 1 Helicase conserved C-terminal domain zf-PARP PF00645.18 CBZ27643.1 - 2.4e-12 47.5 0.1 9.4e-12 45.6 0.1 2.1 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region zf-RING_2 PF13639.6 CBZ27643.1 - 1.5e-06 28.4 3.6 1.5e-06 28.4 3.6 3.0 3 0 0 3 3 2 1 Ring finger domain zf-C3HC4_2 PF13923.6 CBZ27643.1 - 1.3e-05 25.0 4.6 7.4e-05 22.5 4.6 2.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 CBZ27643.1 - 5e-05 23.0 2.2 0.00013 21.6 2.2 1.7 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4 PF00097.25 CBZ27643.1 - 0.00012 21.8 3.2 0.00012 21.8 3.2 3.5 4 0 0 4 4 3 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 CBZ27643.1 - 0.00055 20.2 3.0 0.0032 17.7 3.0 2.4 1 0 0 1 1 1 1 RING-H2 zinc finger domain ERCC3_RAD25_C PF16203.5 CBZ27643.1 - 0.0011 18.2 0.0 0.0026 17.0 0.0 1.5 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase ResIII PF04851.15 CBZ27643.1 - 0.0042 17.1 0.0 1.1 9.3 0.0 2.6 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit zf-ANAPC11 PF12861.7 CBZ27643.1 - 0.011 15.8 1.1 0.049 13.7 1.1 2.1 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.6 CBZ27643.1 - 0.048 13.7 3.3 0.2 11.7 3.3 2.2 1 0 0 1 1 1 0 RING-type zinc-finger PP2C PF00481.21 CBZ27644.1 - 1.9e-50 171.9 0.1 2.5e-50 171.5 0.1 1.1 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 CBZ27644.1 - 0.0011 18.6 0.0 0.0022 17.7 0.0 1.4 1 0 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.12 CBZ27644.1 - 0.0056 16.6 0.0 0.025 14.5 0.0 1.9 2 0 0 2 2 2 1 Stage II sporulation protein E (SpoIIE) TIP39 PF14980.6 CBZ27644.1 - 0.0066 16.3 0.0 0.027 14.4 0.0 2.0 2 0 0 2 2 2 1 TIP39 peptide Luciferase_N PF05295.11 CBZ27644.1 - 0.037 14.0 0.0 0.092 12.8 0.0 1.6 1 0 0 1 1 1 0 Luciferase/LBP N-terminal domain Spore_III_AB PF09548.10 CBZ27644.1 - 0.044 13.9 0.0 1.3 9.1 0.0 2.5 2 0 0 2 2 2 0 Stage III sporulation protein AB (spore_III_AB) Ank_2 PF12796.7 CBZ27648.1 - 7.2e-08 32.9 1.4 0.019 15.5 0.0 4.7 3 2 4 7 7 7 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CBZ27648.1 - 8e-08 32.7 0.6 0.0072 16.9 0.0 4.6 3 1 0 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 CBZ27648.1 - 0.0048 17.3 0.1 0.18 12.5 0.0 3.2 2 0 0 2 2 2 1 Ankyrin repeat DUF3318 PF11780.8 CBZ27648.1 - 0.18 11.8 3.1 22 5.0 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3318) zf-DNL PF05180.12 CBZ27649.1 - 9.2e-28 96.0 0.1 1.6e-27 95.2 0.1 1.4 1 0 0 1 1 1 1 DNL zinc finger zf-RING_4 PF14570.6 CBZ27649.1 - 0.058 13.2 0.2 0.12 12.2 0.2 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zinc_ribbon_4 PF13717.6 CBZ27649.1 - 0.1 12.6 0.1 0.27 11.2 0.0 1.7 2 0 0 2 2 2 0 zinc-ribbon domain Cyclin_N PF00134.23 CBZ27650.1 - 4.7e-07 29.6 0.2 0.0007 19.3 0.0 3.4 3 0 0 3 3 3 2 Cyclin, N-terminal domain TFIIB_C_1 PF18542.1 CBZ27650.1 - 0.2 11.7 2.5 0.68 10.0 2.5 1.9 1 0 0 1 1 1 0 Transcription factor IIB C-terminal module 1 Prefoldin_2 PF01920.20 CBZ27651.1 - 8.9e-11 41.7 0.8 1.1e-10 41.4 0.8 1.1 1 0 0 1 1 1 1 Prefoldin subunit Prefoldin PF02996.17 CBZ27651.1 - 3.8e-05 23.6 1.6 0.012 15.5 0.2 2.1 2 0 0 2 2 2 2 Prefoldin subunit DUF4140 PF13600.6 CBZ27651.1 - 0.011 16.2 1.1 2.5 8.6 0.1 2.1 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) XhlA PF10779.9 CBZ27651.1 - 0.012 15.8 3.3 1.1 9.5 0.7 2.1 2 0 0 2 2 2 0 Haemolysin XhlA CdvA PF18822.1 CBZ27651.1 - 0.013 15.3 0.8 0.024 14.5 0.8 1.4 1 1 0 1 1 1 0 CdvA-like coiled-coil domain FlaC_arch PF05377.11 CBZ27651.1 - 0.018 15.4 0.5 8.1 6.9 0.1 2.3 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) TPR_MLP1_2 PF07926.12 CBZ27651.1 - 0.02 15.0 1.5 0.47 10.5 0.4 2.1 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein DUF5082 PF16888.5 CBZ27651.1 - 0.021 15.1 0.9 1.1 9.6 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF5082) CCDC-167 PF15188.6 CBZ27651.1 - 0.025 14.9 1.1 0.041 14.2 1.1 1.3 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 167 FapA PF03961.13 CBZ27651.1 - 0.036 12.7 0.3 0.042 12.5 0.3 1.0 1 0 0 1 1 1 0 Flagellar Assembly Protein A Med9 PF07544.13 CBZ27651.1 - 0.039 14.0 2.0 3.1 8.0 0.1 2.2 2 0 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 CLZ PF16526.5 CBZ27651.1 - 0.054 13.9 2.3 0.91 9.9 0.4 2.2 2 0 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Baculo_PEP_C PF04513.12 CBZ27651.1 - 0.1 12.6 0.1 0.4 10.7 0.1 1.7 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Spc24 PF08286.11 CBZ27651.1 - 0.19 12.0 2.9 3.3 8.0 2.9 2.1 1 1 0 1 1 1 0 Spc24 subunit of Ndc80 Kdo PF06293.14 CBZ27656.1 - 1.9e-06 27.4 0.0 0.0024 17.3 0.0 2.3 2 0 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 CBZ27656.1 - 0.00093 18.8 0.0 0.99 9.0 0.0 2.2 1 1 1 2 2 2 2 RIO1 family Pkinase PF00069.25 CBZ27656.1 - 0.016 14.6 0.0 0.048 13.0 0.0 1.8 1 1 0 1 1 1 0 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ27656.1 - 0.068 12.4 0.0 0.11 11.7 0.0 1.4 1 1 0 1 1 1 0 Protein tyrosine kinase LRR_8 PF13855.6 CBZ27657.1 - 8.7e-18 63.8 7.2 9e-12 44.6 1.0 2.9 2 1 1 3 3 3 2 Leucine rich repeat LRR_4 PF12799.7 CBZ27657.1 - 3e-11 43.4 2.3 3.9e-06 27.1 0.3 2.7 2 0 0 2 2 2 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 CBZ27657.1 - 0.00086 19.5 5.9 0.055 14.0 0.1 4.1 3 1 1 4 4 4 1 Leucine Rich Repeat PKcGMP_CC PF16808.5 CBZ27657.1 - 0.041 13.8 8.3 0.97 9.3 0.4 4.9 4 0 0 4 4 4 0 Coiled-coil N-terminus of cGMP-dependent protein kinase DUF5535 PF17687.1 CBZ27657.1 - 0.078 13.1 0.5 0.22 11.7 0.5 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5535) LRR_5 PF13306.6 CBZ27657.1 - 0.081 12.9 0.0 0.14 12.1 0.0 1.2 1 0 0 1 1 1 0 BspA type Leucine rich repeat region (6 copies) Ribosomal_L23 PF00276.20 CBZ27658.1 - 4.8e-06 26.8 0.1 7e-06 26.3 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L23 Phage_holin_3_6 PF07332.11 CBZ27659.1 - 0.063 13.3 0.7 0.063 13.3 0.7 2.5 2 1 1 3 3 3 0 Putative Actinobacterial Holin-X, holin superfamily III EXS PF03124.14 CBZ27659.1 - 0.075 12.3 0.2 0.12 11.7 0.2 1.2 1 0 0 1 1 1 0 EXS family Pro_isomerase PF00160.21 CBZ27660.1 - 6.2e-45 153.3 0.0 7e-45 153.1 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD SLBP_RNA_bind PF15247.6 CBZ27661.1 - 1.2e-17 63.7 0.1 4.3e-17 62.0 0.1 2.0 1 0 0 1 1 1 1 Histone RNA hairpin-binding protein RNA-binding domain Ank_4 PF13637.6 CBZ27662.1 - 1e-20 73.8 0.5 3.5e-09 37.0 0.1 3.2 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 CBZ27662.1 - 1.4e-16 60.9 0.1 1.3e-09 38.5 0.0 2.5 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 CBZ27662.1 - 5.4e-13 48.7 2.1 1.3e-05 25.5 0.0 4.6 4 0 0 4 4 4 4 Ankyrin repeat Ank_5 PF13857.6 CBZ27662.1 - 2e-12 47.1 2.8 1.5e-07 31.5 0.1 4.1 2 2 2 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 CBZ27662.1 - 7.4e-12 44.4 0.7 3.9e-05 23.7 0.0 4.8 5 0 0 5 5 5 2 Ankyrin repeat PUB PF09409.10 CBZ27664.1 - 0.041 13.8 0.0 0.083 12.8 0.0 1.5 1 0 0 1 1 1 0 PUB domain Tubulin PF00091.25 CBZ27665.1 - 3e-67 226.7 0.0 4.4e-67 226.1 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 CBZ27665.1 - 2.9e-44 150.2 0.2 5.9e-44 149.3 0.2 1.5 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 CBZ27665.1 - 1.1e-05 25.8 0.0 3.5e-05 24.1 0.0 1.9 1 1 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_2 PF13809.6 CBZ27665.1 - 0.003 16.8 0.0 0.005 16.1 0.0 1.3 1 0 0 1 1 1 1 Tubulin like Tubulin_3 PF14881.6 CBZ27665.1 - 0.039 13.6 0.0 0.097 12.4 0.0 1.6 2 0 0 2 2 2 0 Tubulin domain EF-hand_7 PF13499.6 CBZ27666.1 - 0.00012 22.5 0.0 0.12 12.8 0.0 3.8 4 0 0 4 4 4 1 EF-hand domain pair EF-hand_6 PF13405.6 CBZ27666.1 - 0.075 13.0 0.0 10 6.4 0.0 3.2 3 0 0 3 3 3 0 EF-hand domain EF-hand_8 PF13833.6 CBZ27666.1 - 0.076 12.9 0.0 0.2 11.5 0.0 1.7 1 0 0 1 1 1 0 EF-hand domain pair AAA_6 PF12774.7 CBZ27667.1 - 3.8e-145 482.9 1.3 3.4e-143 476.5 0.0 3.4 3 0 0 3 3 3 1 Hydrolytic ATP binding site of dynein motor region DHC_N1 PF08385.12 CBZ27667.1 - 2.1e-142 475.6 14.0 2.1e-142 475.6 14.0 2.9 2 0 0 2 2 2 1 Dynein heavy chain, N-terminal region 1 DHC_N2 PF08393.13 CBZ27667.1 - 3.9e-114 381.9 2.4 3.9e-114 381.9 2.4 3.7 4 0 0 4 4 4 1 Dynein heavy chain, N-terminal region 2 AAA_8 PF12780.7 CBZ27667.1 - 8.2e-87 290.8 0.0 2.2e-86 289.4 0.0 1.8 1 0 0 1 1 1 1 P-loop containing dynein motor region D4 Dynein_C PF18199.1 CBZ27667.1 - 2.3e-78 263.5 0.4 3.6e-77 259.6 0.0 2.6 2 0 0 2 2 2 1 Dynein heavy chain C-terminal domain AAA_9 PF12781.7 CBZ27667.1 - 2.3e-77 259.0 6.9 2e-76 255.9 7.3 2.5 2 0 0 2 2 2 1 ATP-binding dynein motor region AAA_7 PF12775.7 CBZ27667.1 - 4.7e-53 179.4 2.8 1.5e-49 167.9 0.0 4.3 4 0 0 4 4 3 2 P-loop containing dynein motor region AAA_lid_11 PF18198.1 CBZ27667.1 - 1.9e-45 154.7 0.1 5.1e-44 150.0 0.0 2.8 2 0 0 2 2 2 1 Dynein heavy chain AAA lid domain MT PF12777.7 CBZ27667.1 - 4e-38 131.3 8.7 4e-38 131.3 8.7 1.7 2 0 0 2 2 2 1 Microtubule-binding stalk of dynein motor Dynein_heavy PF03028.15 CBZ27667.1 - 5.2e-38 129.8 1.5 1.9e-36 124.7 0.1 3.5 4 0 0 4 4 2 1 Dynein heavy chain region D6 P-loop domain Dynein_AAA_lid PF17852.1 CBZ27667.1 - 2.9e-20 72.7 0.2 2.1e-19 69.9 0.2 2.7 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain AAA_5 PF07728.14 CBZ27667.1 - 2.6e-14 53.4 0.0 0.0016 18.5 0.0 5.7 5 1 0 5 5 4 3 AAA domain (dynein-related subfamily) AAA_lid_1 PF17857.1 CBZ27667.1 - 8.3e-12 45.2 0.0 1.6e-10 41.1 0.0 3.1 1 1 0 1 1 1 1 AAA+ lid domain AAA PF00004.29 CBZ27667.1 - 3.2e-06 27.6 2.0 0.049 14.1 0.0 5.4 5 0 0 5 5 5 1 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 CBZ27667.1 - 0.011 16.2 0.1 0.38 11.3 0.0 3.5 3 0 0 3 3 2 0 AAA domain SNF5 PF04855.12 CBZ27667.1 - 0.062 13.1 2.9 6.4 6.5 0.1 3.3 3 0 0 3 3 2 0 SNF5 / SMARCB1 / INI1 PET PF06297.14 CBZ27667.1 - 0.095 13.0 0.1 0.4 11.0 0.1 2.2 1 0 0 1 1 1 0 PET Domain AAA_22 PF13401.6 CBZ27667.1 - 0.87 9.9 8.8 23 5.2 0.0 5.7 6 0 0 6 6 6 0 AAA domain Complex1_LYR PF05347.15 CBZ27668.1 - 2.2e-05 24.4 0.0 5e-05 23.3 0.0 1.6 1 1 0 1 1 1 1 Complex 1 protein (LYR family) 2OG-FeII_Oxy PF03171.20 CBZ27670.1 - 1.7e-14 54.2 0.0 3.1e-14 53.3 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.6 CBZ27670.1 - 0.01 16.6 0.0 1.1 10.1 0.0 2.5 2 0 0 2 2 2 0 non-haem dioxygenase in morphine synthesis N-terminal PrlF_antitoxin PF15937.5 CBZ27670.1 - 0.077 13.4 0.0 0.15 12.5 0.0 1.5 1 0 0 1 1 1 0 prlF antitoxin for toxin YhaV_toxin SecE PF00584.20 CBZ27671.1 - 3.1e-13 49.4 0.5 3.7e-13 49.2 0.5 1.1 1 0 0 1 1 1 1 SecE/Sec61-gamma subunits of protein translocation complex NAD_binding_2 PF03446.15 CBZ27672.1 - 1.1e-30 106.9 0.1 1.8e-30 106.2 0.1 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 CBZ27672.1 - 3.4e-13 49.9 0.3 2.2e-11 44.0 0.1 2.6 2 0 0 2 2 2 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase Shikimate_DH PF01488.20 CBZ27672.1 - 9.5e-05 22.5 0.4 0.0055 16.8 0.1 2.3 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase F420_oxidored PF03807.17 CBZ27672.1 - 0.0032 18.0 0.1 0.028 15.0 0.0 2.4 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent GFO_IDH_MocA PF01408.22 CBZ27672.1 - 0.0092 16.8 0.0 1.2 10.0 0.0 2.9 2 1 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold 3HCDH_N PF02737.18 CBZ27672.1 - 0.14 12.0 0.0 0.27 11.1 0.0 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain SpoIISA_toxin PF14171.6 CBZ27674.1 - 0.025 14.3 0.0 0.038 13.7 0.0 1.2 1 0 0 1 1 1 0 Toxin SpoIISA, type II toxin-antitoxin system NPV_P10 PF05531.12 CBZ27674.1 - 0.049 14.1 1.6 0.17 12.3 0.1 2.6 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein Tup_N PF08581.10 CBZ27674.1 - 0.41 11.0 4.3 0.39 11.1 0.2 2.5 3 0 0 3 3 3 0 Tup N-terminal His_kinase PF06580.13 CBZ27674.1 - 0.97 9.8 2.8 0.7 10.3 0.8 1.8 2 0 0 2 2 2 0 Histidine kinase BBP1_C PF15272.6 CBZ27674.1 - 2 8.2 5.5 0.39 10.5 1.1 2.0 2 0 0 2 2 2 0 Spindle pole body component BBP1, C-terminal Frataxin_Cyay PF01491.16 CBZ27675.1 - 2.3e-28 98.4 0.0 2.9e-28 98.1 0.0 1.1 1 0 0 1 1 1 1 Frataxin-like domain Prefoldin_3 PF13758.6 CBZ27676.1 - 0.4 10.8 19.2 92 3.2 0.1 9.2 2 1 13 15 15 15 0 Prefoldin subunit Vps35 PF03635.17 CBZ27676.1 - 0.43 9.0 8.3 11 4.3 8.3 2.5 1 1 0 1 1 1 0 Vacuolar protein sorting-associated protein 35 Glyco_hydro_99 PF16317.5 CBZ27676.1 - 0.63 9.1 4.1 1.9e+02 0.9 0.0 4.6 1 1 7 8 8 8 0 Glycosyl hydrolase family 99 RRM_1 PF00076.22 CBZ27678.1 - 0.00075 19.3 0.1 0.0014 18.4 0.1 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF2652 PF10851.8 CBZ27678.1 - 0.0057 16.8 0.0 0.01 16.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2652) CorA PF01544.18 CBZ27679.1 - 6.7e-19 68.3 0.0 1.3e-18 67.3 0.0 1.4 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein DUF1217 PF06748.12 CBZ27679.1 - 0.17 11.9 0.0 0.3 11.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1217) DnaJ_C PF01556.18 CBZ27680.1 - 5.6e-30 104.4 0.0 8.5e-30 103.8 0.0 1.3 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 CBZ27680.1 - 1.8e-17 63.2 0.3 3.6e-17 62.2 0.3 1.5 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 CBZ27680.1 - 2.1e-14 53.6 12.8 3.8e-14 52.8 12.8 1.4 1 0 0 1 1 1 1 DnaJ central domain Anti-TRAP PF15777.5 CBZ27680.1 - 2.3e-08 33.8 6.5 0.0015 18.5 1.1 2.4 2 0 0 2 2 2 2 Tryptophan RNA-binding attenuator protein inhibitory protein T6SS_TssF PF05947.12 CBZ27680.1 - 0.075 11.6 0.0 0.13 10.8 0.0 1.2 1 0 0 1 1 1 0 Type VI secretion system, TssF TackOD1 PF18551.1 CBZ27680.1 - 0.81 9.3 8.4 0.25 11.0 0.8 2.2 1 1 1 2 2 2 0 Thaumarchaeal output domain 1 Zn_ribbon_SprT PF17283.2 CBZ27680.1 - 1 9.3 12.7 2.3 8.2 4.1 3.4 1 1 0 2 2 2 0 SprT-like zinc ribbon domain HypA PF01155.19 CBZ27680.1 - 1.4 8.9 11.2 2.2 8.3 2.2 2.3 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Lar_restr_allev PF14354.6 CBZ27680.1 - 2.7 8.4 8.3 15 6.0 3.3 3.4 1 1 1 2 2 2 0 Restriction alleviation protein Lar DUF1356 PF07092.12 CBZ27680.1 - 3 7.0 8.1 0.79 8.9 0.6 2.8 1 1 2 3 3 3 0 Protein of unknown function (DUF1356) zinc_ribbon_9 PF14369.6 CBZ27680.1 - 3.1 8.1 13.3 5.3 7.4 2.2 3.6 2 2 1 3 3 3 0 zinc-ribbon DZR PF12773.7 CBZ27680.1 - 3.3 7.8 11.7 41 4.3 11.8 2.1 1 1 0 1 1 1 0 Double zinc ribbon zf-CCHC_5 PF14787.6 CBZ27680.1 - 3.9 7.3 11.7 0.086 12.6 3.9 2.2 2 0 0 2 2 2 0 GAG-polyprotein viral zinc-finger zinc-ribbons_6 PF07191.12 CBZ27680.1 - 6.8 6.8 9.5 59 3.8 9.5 2.1 1 1 0 1 1 1 0 zinc-ribbons Kelch_4 PF13418.6 CBZ27681.1 - 3.4e-06 27.0 0.1 0.00086 19.3 0.1 3.0 2 0 0 2 2 2 1 Galactose oxidase, central domain Kelch_1 PF01344.25 CBZ27681.1 - 0.00089 18.8 0.0 0.081 12.5 0.2 3.1 2 0 0 2 2 2 1 Kelch motif Kelch_6 PF13964.6 CBZ27681.1 - 0.003 17.8 0.0 0.93 9.9 0.0 2.9 2 0 0 2 2 2 1 Kelch motif Kelch_3 PF13415.6 CBZ27681.1 - 0.0038 17.5 0.3 0.0038 17.5 0.3 4.1 3 0 0 3 3 3 1 Galactose oxidase, central domain Kelch_5 PF13854.6 CBZ27681.1 - 0.99 9.5 3.3 48 4.1 0.1 3.6 3 0 0 3 3 3 0 Kelch motif Aldedh PF00171.22 CBZ27682.1 - 9.7e-176 584.8 0.2 1.1e-175 584.6 0.2 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.11 CBZ27682.1 - 0.074 12.5 0.0 0.16 11.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1487) SBP_bac_3 PF00497.20 CBZ27683.1 - 0.021 14.3 0.0 2.7 7.4 0.0 2.0 2 0 0 2 2 2 0 Bacterial extracellular solute-binding proteins, family 3 SMI1_KNR4 PF09346.10 CBZ27684.1 - 0.0038 17.6 0.1 0.011 16.1 0.0 1.8 2 0 0 2 2 2 1 SMI1 / KNR4 family (SUKH-1) Acetyltransf_16 PF05301.11 CBZ27685.1 - 1e-48 165.4 0.0 1.2e-48 165.2 0.0 1.1 1 0 0 1 1 1 1 GNAT acetyltransferase, Mec-17 Acetyltransf_7 PF13508.7 CBZ27685.1 - 0.00076 19.9 0.0 0.0017 18.8 0.0 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 CBZ27685.1 - 0.0019 18.4 0.0 0.0038 17.5 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 CBZ27685.1 - 0.024 14.6 0.0 0.097 12.6 0.0 1.8 1 1 0 2 2 2 0 Acetyltransferase (GNAT) domain LMBR1 PF04791.16 CBZ27686.1 - 6.5e-29 101.2 30.1 9.3e-21 74.3 8.7 2.0 1 1 0 2 2 2 2 LMBR1-like membrane protein DUF3810 PF12725.7 CBZ27686.1 - 0.0055 16.1 0.6 0.0055 16.1 0.6 3.9 1 1 2 4 4 4 1 Protein of unknown function (DUF3810) DUF2721 PF11026.8 CBZ27686.1 - 0.15 11.9 0.1 0.15 11.9 0.1 5.6 4 2 2 6 6 6 0 Protein of unknown function (DUF2721) ATP-synt_ab PF00006.25 CBZ27687.1 - 6.1e-64 215.6 0.1 2.7e-63 213.5 0.0 2.0 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N PF02874.23 CBZ27687.1 - 1.2e-12 48.2 0.2 2.8e-12 47.0 0.2 1.7 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain AAA PF00004.29 CBZ27687.1 - 0.0046 17.4 0.1 0.029 14.8 0.0 2.2 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 CBZ27687.1 - 0.015 14.9 0.2 0.095 12.3 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.6 CBZ27687.1 - 0.016 15.6 1.5 0.28 11.5 0.4 2.4 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.22 CBZ27687.1 - 0.035 13.3 0.0 0.073 12.2 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain ATPase PF06745.13 CBZ27687.1 - 0.036 13.4 0.1 0.062 12.6 0.1 1.4 1 0 0 1 1 1 0 KaiC RsgA_GTPase PF03193.16 CBZ27687.1 - 0.072 13.0 0.1 0.16 11.9 0.1 1.6 1 0 0 1 1 1 0 RsgA GTPase ATPase_2 PF01637.18 CBZ27687.1 - 0.1 12.5 0.1 0.25 11.2 0.0 1.6 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea ATP-synt_ab PF00006.25 CBZ27688.1 - 1.3e-63 214.5 0.0 2.4e-63 213.6 0.0 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N PF02874.23 CBZ27688.1 - 1.2e-12 48.1 0.2 2.6e-12 47.1 0.2 1.6 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain AAA PF00004.29 CBZ27688.1 - 0.013 15.9 0.0 0.027 14.9 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ATPase PF06745.13 CBZ27688.1 - 0.037 13.4 0.1 0.057 12.8 0.1 1.3 1 0 0 1 1 1 0 KaiC AAA_25 PF13481.6 CBZ27688.1 - 0.042 13.4 0.0 0.087 12.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.22 CBZ27688.1 - 0.043 13.0 0.0 0.068 12.4 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain RsgA_GTPase PF03193.16 CBZ27688.1 - 0.085 12.7 0.1 0.15 12.0 0.1 1.3 1 0 0 1 1 1 0 RsgA GTPase AAA_19 PF13245.6 CBZ27688.1 - 0.094 13.1 0.3 0.24 11.7 0.3 1.6 1 0 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 CBZ27688.1 - 0.14 12.1 0.0 0.23 11.4 0.0 1.3 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea Ribosomal_S25 PF03297.15 CBZ27689.1 - 2e-36 124.2 5.4 2.3e-36 124.0 5.4 1.1 1 0 0 1 1 1 1 S25 ribosomal protein DUF3516 PF12029.8 CBZ27689.1 - 0.13 11.3 1.4 0.17 10.9 1.4 1.2 1 1 0 1 1 1 0 Domain of unknown function (DUF3516) DNA_methylase PF00145.17 CBZ27690.1 - 7.3e-38 130.8 0.0 1.7e-29 103.2 0.0 3.6 2 1 0 2 2 2 2 C-5 cytosine-specific DNA methylase PQQ_3 PF13570.6 CBZ27691.1 - 0.0073 16.8 2.1 1.9 9.1 0.2 4.9 4 0 0 4 4 4 1 PQQ-like domain zinc_ribbon_16 PF17034.5 CBZ27694.1 - 8e-09 35.8 8.5 8e-09 35.8 8.5 2.2 1 1 1 2 2 2 1 Zinc-ribbon like family zf-RING_2 PF13639.6 CBZ27694.1 - 0.3 11.4 7.4 1 9.8 7.4 1.9 1 0 0 1 1 1 0 Ring finger domain DUF776 PF05604.11 CBZ27694.1 - 0.55 10.6 3.7 0.22 11.9 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF776) zinc_ribbon_16 PF17034.5 CBZ27695.1 - 0.0015 18.7 23.9 0.026 14.8 23.9 2.3 1 1 0 1 1 1 1 Zinc-ribbon like family AKNA PF12443.8 CBZ27696.1 - 0.17 12.5 1.2 0.32 11.7 0.0 2.1 2 0 0 2 2 2 0 AT-hook-containing transcription factor Surfac_D-trimer PF09006.11 CBZ27696.1 - 0.26 11.2 0.5 4.1 7.4 0.6 2.3 2 0 0 2 2 2 0 Lung surfactant protein D coiled-coil trimerisation BSD PF03909.17 CBZ27696.1 - 0.59 10.2 2.4 0.93 9.5 0.2 2.3 3 0 0 3 3 3 0 BSD domain Cullin PF00888.22 CBZ27697.1 - 3.4e-49 168.0 0.0 1.9e-48 165.6 0.0 2.0 1 1 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 CBZ27697.1 - 2.8e-08 33.7 0.0 9.2e-08 32.0 0.0 1.9 1 0 0 1 1 1 1 Cullin protein neddylation domain NPL4 PF05021.15 CBZ27698.1 - 2.2e-15 56.8 0.0 1.2e-08 34.7 0.0 2.3 2 0 0 2 2 2 2 NPL4 family PRP38 PF03371.15 CBZ27699.1 - 3.5e-05 23.7 0.0 6e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 PRP38 family MbeB_N PF04837.12 CBZ27699.1 - 0.042 14.2 0.0 0.13 12.6 0.0 1.8 2 0 0 2 2 2 0 MbeB-like, N-term conserved region Spore_YtfJ PF09579.10 CBZ27699.1 - 0.67 10.1 2.6 0.71 10.1 0.0 2.4 3 0 0 3 3 3 0 Sporulation protein YtfJ (Spore_YtfJ) PPP4R2 PF09184.11 CBZ27700.1 - 0.00026 20.7 0.0 0.00039 20.1 0.0 1.2 1 0 0 1 1 1 1 PPP4R2 RNA_pol_N PF01194.17 CBZ27701.1 - 2.6e-29 101.3 0.5 3.2e-29 101.0 0.5 1.1 1 0 0 1 1 1 1 RNA polymerases N / 8 kDa subunit Metallophos PF00149.28 CBZ27702.1 - 1.4e-33 117.2 1.1 1.9e-33 116.7 1.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase GIY-YIG PF01541.24 CBZ27703.1 - 5.4e-11 42.6 0.0 9.3e-11 41.9 0.0 1.4 1 0 0 1 1 1 1 GIY-YIG catalytic domain RNF220 PF15926.5 CBZ27703.1 - 0.23 11.1 0.0 0.36 10.4 0.0 1.3 1 0 0 1 1 1 0 E3 ubiquitin-protein ligase RNF220 Sec23_trunk PF04811.15 CBZ27704.1 - 1.3e-38 132.9 0.0 2.1e-38 132.3 0.0 1.3 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.15 CBZ27704.1 - 1e-20 73.5 0.0 1.9e-20 72.6 0.0 1.5 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.12 CBZ27704.1 - 6.1e-17 62.2 0.1 1.2e-16 61.2 0.1 1.5 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.15 CBZ27704.1 - 3.2e-10 39.9 1.1 9.8e-10 38.3 1.1 1.9 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger ASH PF15780.5 CBZ27705.1 - 2.1e-08 34.2 8.5 9.1e-05 22.6 0.2 6.0 6 0 0 6 6 6 2 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin TMEM131_like PF12371.8 CBZ27705.1 - 0.12 12.7 2.7 0.66 10.3 0.1 3.7 5 0 0 5 5 5 0 Transmembrane protein 131-like SKA1 PF07160.12 CBZ27705.1 - 1.6 8.5 3.5 3.9 7.3 3.5 1.6 1 0 0 1 1 1 0 Spindle and kinetochore-associated protein 1 VCPO_N PF17897.1 CBZ27706.1 - 0.048 13.5 0.3 0.11 12.3 0.3 1.5 1 0 0 1 1 1 0 Vanadium chloroperoxidase N-terminal domain TAP42 PF04177.12 CBZ27707.1 - 7.8e-46 156.7 7.3 1.3e-44 152.7 7.3 2.0 1 1 0 1 1 1 1 TAP42-like family DUF3153 PF11353.8 CBZ27708.1 - 0.12 12.0 0.4 13 5.3 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3153) ATP_bind_1 PF03029.17 CBZ27709.1 - 2e-61 207.8 0.0 2.3e-61 207.6 0.0 1.0 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_30 PF13604.6 CBZ27709.1 - 0.00024 20.9 0.0 0.0003 20.6 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 CBZ27709.1 - 0.00053 20.5 0.0 0.0014 19.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.27 CBZ27709.1 - 0.0017 18.9 0.0 0.0033 17.9 0.0 1.4 1 0 0 1 1 1 1 ABC transporter SRP54 PF00448.22 CBZ27709.1 - 0.0027 17.4 0.0 0.0054 16.4 0.0 1.5 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain AAA_22 PF13401.6 CBZ27709.1 - 0.0055 17.0 0.0 0.0099 16.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain CLP1_P PF16575.5 CBZ27709.1 - 0.0077 16.1 0.0 0.018 14.8 0.0 1.6 2 0 0 2 2 2 1 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_16 PF13191.6 CBZ27709.1 - 0.0096 16.3 0.0 0.019 15.4 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 CBZ27709.1 - 0.018 14.8 0.1 0.039 13.7 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain GTP_EFTU PF00009.27 CBZ27709.1 - 0.023 14.2 0.0 1 8.9 0.0 2.5 3 0 0 3 3 3 0 Elongation factor Tu GTP binding domain Cytidylate_kin PF02224.18 CBZ27709.1 - 0.025 14.3 0.1 0.041 13.6 0.1 1.3 1 0 0 1 1 1 0 Cytidylate kinase AAA_28 PF13521.6 CBZ27709.1 - 0.027 14.7 0.0 0.043 14.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 CBZ27709.1 - 0.041 14.0 0.0 0.35 11.0 0.0 2.2 1 1 0 1 1 1 0 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 CBZ27709.1 - 0.045 13.7 0.0 0.38 10.6 0.0 2.3 3 0 0 3 3 3 0 RsgA GTPase AAA_17 PF13207.6 CBZ27709.1 - 0.046 14.2 0.1 0.15 12.5 0.1 1.8 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 CBZ27709.1 - 0.048 14.1 0.1 0.22 11.9 0.0 2.1 2 0 0 2 2 2 0 RNA helicase PduV-EutP PF10662.9 CBZ27709.1 - 0.054 13.2 0.0 3 7.6 0.0 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_25 PF13481.6 CBZ27709.1 - 0.11 12.1 0.4 0.32 10.6 0.1 1.8 3 0 0 3 3 3 0 AAA domain AAA_5 PF07728.14 CBZ27709.1 - 0.17 11.9 0.0 0.28 11.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Surp PF01805.20 CBZ27710.1 - 5.7e-15 55.0 1.5 6.8e-12 45.2 0.1 2.4 2 0 0 2 2 2 2 Surp module DNA_pol_D_N PF18018.1 CBZ27711.1 - 2.5e-27 95.5 0.0 5.1e-27 94.5 0.0 1.5 1 0 0 1 1 1 1 DNA polymerase delta subunit OB-fold domain DNA_pol_E_B PF04042.16 CBZ27711.1 - 8.8e-24 84.0 1.6 1.2e-21 77.0 1.6 2.2 1 1 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B DUF2937 PF11157.8 CBZ27711.1 - 0.4 10.4 0.0 0.4 10.4 0.0 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2937) Ras PF00071.22 CBZ27712.1 - 2.1e-50 170.5 0.0 2.6e-50 170.2 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CBZ27712.1 - 6.2e-32 110.3 0.0 1.1e-31 109.5 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CBZ27712.1 - 5.2e-11 42.3 0.0 7.1e-11 41.9 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 CBZ27712.1 - 0.00027 20.4 0.0 0.00037 19.9 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RNA_helicase PF00910.22 CBZ27712.1 - 0.00033 21.0 0.2 0.0021 18.4 0.2 2.0 1 1 0 1 1 1 1 RNA helicase MMR_HSR1 PF01926.23 CBZ27712.1 - 0.00033 20.7 0.0 0.00054 20.0 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase G-alpha PF00503.20 CBZ27712.1 - 0.0068 15.6 1.1 1.2 8.2 0.1 2.7 2 1 1 3 3 3 1 G-protein alpha subunit RsgA_GTPase PF03193.16 CBZ27712.1 - 0.008 16.1 0.0 2.9 7.8 0.0 2.3 2 0 0 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 CBZ27712.1 - 0.018 14.6 0.4 0.071 12.6 0.0 1.9 1 1 1 2 2 2 0 Elongation factor Tu GTP binding domain AAA_7 PF12775.7 CBZ27712.1 - 0.029 13.9 0.0 0.045 13.3 0.0 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_33 PF13671.6 CBZ27712.1 - 0.036 14.2 0.0 0.054 13.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain Pox_A32 PF04665.12 CBZ27712.1 - 0.041 13.3 0.1 0.075 12.5 0.1 1.4 1 0 0 1 1 1 0 Poxvirus A32 protein cobW PF02492.19 CBZ27712.1 - 0.079 12.5 0.1 3.7 7.1 0.1 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_16 PF13191.6 CBZ27712.1 - 0.08 13.3 0.0 0.15 12.5 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain TsaE PF02367.17 CBZ27712.1 - 0.094 12.7 0.0 0.18 11.8 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_24 PF13479.6 CBZ27712.1 - 0.098 12.4 0.1 0.13 11.9 0.1 1.3 1 0 0 1 1 1 0 AAA domain Septin PF00735.18 CBZ27712.1 - 0.1 11.8 0.0 0.16 11.3 0.0 1.3 1 0 0 1 1 1 0 Septin Cluap1 PF10234.9 CBZ27713.1 - 2.8e-89 299.1 14.1 3.8e-89 298.7 14.1 1.2 1 0 0 1 1 1 1 Clusterin-associated protein-1 Lectin_N PF03954.14 CBZ27713.1 - 0.57 9.9 6.3 0.15 11.8 0.8 2.5 2 1 0 2 2 2 0 Hepatic lectin, N-terminal domain Atg14 PF10186.9 CBZ27713.1 - 1 8.4 10.9 1.8 7.6 10.9 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF4407 PF14362.6 CBZ27713.1 - 1.9 7.8 15.2 4.8 6.4 15.2 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) She9_MDM33 PF05546.11 CBZ27713.1 - 2.8 7.7 18.0 0.28 10.9 12.7 1.9 2 0 0 2 2 2 0 She9 / Mdm33 family Jnk-SapK_ap_N PF09744.9 CBZ27713.1 - 4.3 7.6 20.3 5.2 7.3 11.5 2.6 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 FUSC PF04632.12 CBZ27713.1 - 7.8 4.9 7.3 12 4.2 7.3 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family RNase_T PF00929.24 CBZ27714.1 - 3.8e-06 27.5 0.0 6.1e-06 26.9 0.0 1.3 1 0 0 1 1 1 1 Exonuclease DUF1295 PF06966.12 CBZ27716.1 - 2.5e-09 37.0 1.4 3.3e-09 36.6 0.6 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF1295) PEMT PF04191.13 CBZ27716.1 - 0.00018 21.9 1.0 0.00018 21.9 1.0 1.9 2 0 0 2 2 2 1 Phospholipid methyltransferase Steroid_dh PF02544.16 CBZ27716.1 - 0.00086 19.3 1.8 0.00092 19.2 0.7 1.7 1 1 1 2 2 2 1 3-oxo-5-alpha-steroid 4-dehydrogenase Rod_cone_degen PF15201.6 CBZ27716.1 - 0.09 12.9 2.1 0.12 12.5 0.7 1.9 2 0 0 2 2 2 0 Progressive rod-cone degeneration PCRF PF03462.18 CBZ27717.1 - 6.7e-30 104.4 0.3 6.7e-30 104.4 0.3 1.8 2 0 0 2 2 2 1 PCRF domain RF-1 PF00472.20 CBZ27717.1 - 2.7e-26 91.8 0.2 2.7e-26 91.8 0.2 1.7 2 0 0 2 2 2 1 RF-1 domain CsiV PF10972.8 CBZ27717.1 - 0.019 14.7 0.0 0.024 14.4 0.0 1.2 1 0 0 1 1 1 0 Peptidoglycan-binding protein, CsiV Dict-STAT-coil PF09267.10 CBZ27717.1 - 1 9.8 4.2 0.33 11.3 0.9 1.8 2 0 0 2 2 2 0 Dictyostelium STAT, coiled coil DUF1126 PF06565.12 CBZ27718.1 - 2.3e-68 226.6 0.2 6.7e-26 90.2 0.0 3.5 3 0 0 3 3 3 3 DUF1126 PH-like domain EF-hand_7 PF13499.6 CBZ27718.1 - 0.031 14.7 0.4 1 9.8 0.0 3.1 2 1 0 2 2 2 0 EF-hand domain pair Cyclin_N PF00134.23 CBZ27719.1 - 1.4e-38 131.5 0.3 1.9e-38 131.1 0.3 1.2 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 CBZ27719.1 - 5.4e-11 42.6 0.0 9.3e-11 41.9 0.0 1.4 1 0 0 1 1 1 1 Cyclin, C-terminal domain NfI_DNAbd_pre-N PF10524.9 CBZ27719.1 - 0.045 13.6 0.0 0.098 12.5 0.0 1.6 1 0 0 1 1 1 0 Nuclear factor I protein pre-N-terminus Peptidase_C2 PF00648.21 CBZ27720.1 - 8.1e-65 218.8 0.1 1.1e-64 218.4 0.1 1.2 1 0 0 1 1 1 1 Calpain family cysteine protease DUF1935 PF09149.10 CBZ27720.1 - 2.6e-22 79.1 0.1 6.1e-22 78.0 0.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1935) Rab3-GTPase_cat PF13890.6 CBZ27721.1 - 1.3e-39 135.4 0.1 2.7e-39 134.4 0.1 1.4 1 0 0 1 1 1 1 Rab3 GTPase-activating protein catalytic subunit Carb_kinase PF01256.17 CBZ27723.1 - 0.059 12.8 0.1 0.13 11.7 0.1 1.6 1 0 0 1 1 1 0 Carbohydrate kinase Pkinase PF00069.25 CBZ27724.1 - 2e-42 145.4 0.0 2.7e-42 145.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ27724.1 - 6.9e-30 104.2 0.0 9.4e-30 103.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CBZ27724.1 - 1.3e-06 27.4 0.0 2.2e-06 26.7 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 CBZ27724.1 - 0.00089 18.7 0.0 0.0014 18.0 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 CBZ27724.1 - 0.0043 17.0 0.4 0.043 13.7 0.1 2.4 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 CBZ27724.1 - 0.12 11.7 0.0 0.2 11.0 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family ABC_ATPase PF09818.9 CBZ27726.1 - 6.8e-173 575.6 0.0 8.9e-173 575.2 0.0 1.1 1 0 0 1 1 1 1 Predicted ATPase of the ABC class AAA_23 PF13476.6 CBZ27726.1 - 0.003 18.1 0.0 0.0048 17.4 0.0 1.2 1 0 0 1 1 1 1 AAA domain zf-Tim10_DDP PF02953.15 CBZ27727.1 - 0.00069 19.2 0.1 0.0012 18.4 0.1 1.4 1 0 0 1 1 1 1 Tim10/DDP family zinc finger Antimicrobial21 PF14861.6 CBZ27727.1 - 0.087 12.5 0.3 3.3 7.5 0.0 2.2 2 0 0 2 2 2 0 Plant antimicrobial peptide Pkinase PF00069.25 CBZ27728.1 - 1.1e-26 93.8 0.0 7.1e-15 55.1 0.0 3.5 3 1 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ27728.1 - 2.1e-06 27.2 0.0 0.2 10.9 0.0 3.2 3 0 0 3 3 3 3 Protein tyrosine kinase Pox_ser-thr_kin PF05445.11 CBZ27728.1 - 0.13 11.3 0.1 0.19 10.7 0.1 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase RIO1 PF01163.22 CBZ27728.1 - 0.17 11.5 0.0 0.33 10.5 0.0 1.4 1 0 0 1 1 1 0 RIO1 family TRAPPC-Trs85 PF12739.7 CBZ27729.1 - 2.3e-34 119.1 0.1 4.3e-34 118.2 0.1 1.4 1 0 0 1 1 1 1 ER-Golgi trafficking TRAPP I complex 85 kDa subunit Pkinase PF00069.25 CBZ27730.1 - 1.2e-25 90.4 0.0 2.6e-19 69.6 0.0 2.1 1 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ27730.1 - 4e-12 46.0 0.0 7.4e-08 32.0 0.0 2.2 1 1 1 2 2 2 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 CBZ27730.1 - 6.5e-06 25.2 0.0 9.2e-06 24.7 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 CBZ27730.1 - 0.0034 17.3 0.0 0.045 13.7 0.0 2.3 2 0 0 2 2 2 1 Phosphotransferase enzyme family BRCT PF00533.26 CBZ27731.1 - 0.001 19.4 0.0 0.01 16.2 0.0 2.6 3 0 0 3 3 3 1 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 CBZ27731.1 - 0.0078 16.6 0.0 1.7 9.1 0.0 3.4 3 0 0 3 3 3 1 BRCT domain, a BRCA1 C-terminus domain BRCT_3 PF18428.1 CBZ27731.1 - 0.038 14.1 0.0 8.1 6.6 0.0 2.9 3 0 0 3 3 3 0 BRCA1 C Terminus (BRCT) domain WD40 PF00400.32 CBZ27732.1 - 5.7e-17 61.8 13.1 0.034 15.0 0.0 10.3 10 0 0 10 10 10 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBZ27732.1 - 2.1e-06 27.9 0.3 0.03 14.6 0.0 4.5 5 1 1 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 CBZ27732.1 - 0.21 10.5 0.1 0.61 9.0 0.1 1.8 1 0 0 1 1 1 0 WD40 region of Ge1, enhancer of mRNA-decapping protein JAB PF01398.21 CBZ27733.1 - 7.5e-05 22.7 0.0 0.00023 21.1 0.0 1.8 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease UPF0172 PF03665.13 CBZ27733.1 - 0.089 12.8 0.1 0.22 11.6 0.0 1.7 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0172) Poly_export PF02563.16 CBZ27734.1 - 0.2 11.9 0.0 0.28 11.4 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis/export protein DAGAT PF03982.13 CBZ27735.1 - 1.3e-77 260.7 0.1 1.6e-77 260.3 0.1 1.1 1 0 0 1 1 1 1 Diacylglycerol acyltransferase DUF1016_N PF17761.1 CBZ27736.1 - 0.0029 17.8 0.2 0.012 15.7 0.0 2.0 2 0 0 2 2 2 1 DUF1016 N-terminal domain ribosomal_L24 PF17136.4 CBZ27736.1 - 0.037 14.4 0.1 0.072 13.5 0.1 1.5 1 0 0 1 1 1 0 Ribosomal proteins 50S L24/mitochondrial 39S L24 KOW PF00467.29 CBZ27736.1 - 0.14 12.2 3.9 0.077 13.0 1.4 1.9 2 0 0 2 2 2 0 KOW motif COX6B PF02297.17 CBZ27737.1 - 0.0019 18.4 5.7 0.0052 17.0 5.7 1.7 1 1 0 1 1 1 1 Cytochrome oxidase c subunit VIb CHCH PF06747.13 CBZ27737.1 - 0.0024 17.9 3.9 0.045 13.9 0.3 2.3 2 0 0 2 2 2 2 CHCH domain CX9C PF16860.5 CBZ27737.1 - 0.011 15.7 5.6 0.05 13.6 0.4 2.2 2 0 0 2 2 2 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, Hairy_orange PF07527.13 CBZ27737.1 - 0.14 12.4 1.6 12 6.2 0.1 2.2 2 0 0 2 2 2 0 Hairy Orange UPF0203 PF05254.12 CBZ27737.1 - 0.24 11.7 5.8 0.72 10.1 5.8 1.7 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0203) COX17 PF05051.13 CBZ27737.1 - 0.74 10.2 5.4 1 9.7 2.6 2.0 1 1 1 2 2 2 0 Cytochrome C oxidase copper chaperone (COX17) EFP_N PF08207.12 CBZ27738.1 - 1e-05 25.5 0.3 1.9e-05 24.6 0.3 1.4 1 0 0 1 1 1 1 Elongation factor P (EF-P) KOW-like domain HORMA PF02301.18 CBZ27740.1 - 8.3e-17 61.5 0.0 1.2e-16 60.9 0.0 1.2 1 0 0 1 1 1 1 HORMA domain PTS_2-RNA PF01885.16 CBZ27740.1 - 0.014 15.4 0.0 0.019 15.0 0.0 1.1 1 0 0 1 1 1 0 RNA 2'-phosphotransferase, Tpt1 / KptA family VWA_3 PF13768.6 CBZ27740.1 - 0.063 13.2 0.0 0.12 12.3 0.0 1.4 1 1 0 1 1 1 0 von Willebrand factor type A domain bacHORMA_2 PF18173.1 CBZ27740.1 - 0.11 12.3 0.0 0.35 10.7 0.0 1.8 1 1 1 2 2 2 0 Bacterial HORMA domain 2 TPR_12 PF13424.6 CBZ27741.1 - 9.2e-15 54.7 16.9 1.7e-06 28.2 1.5 5.2 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_2 PF07719.17 CBZ27741.1 - 0.0022 18.0 1.4 5.9 7.3 0.0 4.4 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_6 PF13174.6 CBZ27741.1 - 0.12 13.1 3.2 1.3 9.9 0.1 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat HSCB_C PF07743.13 CBZ27742.1 - 0.00018 21.9 0.7 0.027 15.0 0.0 2.9 2 1 0 2 2 2 1 HSCB C-terminal oligomerisation domain DnaJ PF00226.31 CBZ27742.1 - 0.0044 17.1 3.7 0.016 15.3 1.1 2.4 2 0 0 2 2 2 1 DnaJ domain Exo5 PF09810.9 CBZ27742.1 - 0.0061 16.1 0.5 0.0074 15.8 0.5 1.1 1 0 0 1 1 1 1 Exonuclease V - a 5' deoxyribonuclease DUF4407 PF14362.6 CBZ27742.1 - 0.016 14.5 1.6 0.021 14.2 1.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Spt20 PF12090.8 CBZ27742.1 - 0.024 14.3 4.4 0.032 13.8 4.4 1.2 1 0 0 1 1 1 0 Spt20 family EIF4E-T PF10477.9 CBZ27742.1 - 0.052 12.4 6.2 0.077 11.8 6.2 1.1 1 0 0 1 1 1 0 Nucleocytoplasmic shuttling protein for mRNA cap-binding EIF4E Roughex PF06020.11 CBZ27742.1 - 0.7 8.9 3.9 1 8.4 3.9 1.2 1 0 0 1 1 1 0 Drosophila roughex protein SUIM_assoc PF16619.5 CBZ27742.1 - 6.8 6.8 14.3 5.5 7.1 12.7 1.8 1 1 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 LRR_9 PF14580.6 CBZ27743.1 - 3.6e-11 42.9 0.0 7e-11 41.9 0.0 1.3 1 0 0 1 1 1 1 Leucine-rich repeat LRR_4 PF12799.7 CBZ27743.1 - 4.9e-07 30.0 0.2 0.0006 20.1 0.8 2.6 1 1 1 2 2 2 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CBZ27743.1 - 1.8e-06 27.6 3.6 6.2e-06 25.9 1.0 2.7 2 0 0 2 2 2 1 Leucine rich repeat LRR_1 PF00560.33 CBZ27743.1 - 0.0095 16.4 0.2 3.1 8.7 0.1 3.2 3 0 0 3 3 3 1 Leucine Rich Repeat LRR_6 PF13516.6 CBZ27743.1 - 0.012 15.6 0.1 4.6 7.5 0.0 3.3 3 0 0 3 3 3 0 Leucine Rich repeat Hc1 PF07432.13 CBZ27743.1 - 3.1 8.2 8.5 0.38 11.1 0.7 3.4 2 0 0 2 2 2 0 Histone H1-like protein Hc1 LSM PF01423.22 CBZ27744.1 - 5.1e-14 51.7 0.0 7.7e-14 51.1 0.0 1.3 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 CBZ27744.1 - 0.014 15.5 0.0 0.1 12.8 0.0 2.0 1 1 0 1 1 1 0 Ataxin 2 SM domain LSM14 PF12701.7 CBZ27744.1 - 0.063 13.4 0.0 0.1 12.7 0.0 1.4 1 1 0 1 1 1 0 Scd6-like Sm domain Transket_pyr PF02779.24 CBZ27745.1 - 8e-44 149.4 0.0 1.3e-43 148.7 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 CBZ27745.1 - 8.5e-40 135.5 0.0 1.9e-39 134.4 0.0 1.6 1 0 0 1 1 1 1 Transketolase, C-terminal domain Glyco_transf_5 PF08323.11 CBZ27746.1 - 0.12 12.0 0.0 0.35 10.5 0.0 1.7 1 0 0 1 1 1 0 Starch synthase catalytic domain YycC PF14174.6 CBZ27747.1 - 0.04 13.7 0.1 0.08 12.8 0.1 1.5 1 0 0 1 1 1 0 YycC-like protein DUF2076 PF09849.9 CBZ27748.1 - 0.0057 16.7 2.3 0.0057 16.7 2.3 2.0 2 0 0 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2076) DUF1935 PF09149.10 CBZ27749.1 - 1.9e-27 95.7 0.0 2.3e-27 95.4 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1935) RMI1_N PF08585.12 CBZ27750.1 - 4.4e-11 43.0 0.0 9.9e-11 41.8 0.0 1.6 1 0 0 1 1 1 1 RecQ mediated genome instability protein BRCA-2_OB1 PF09103.10 CBZ27750.1 - 0.066 13.2 0.0 0.14 12.1 0.0 1.6 1 1 0 1 1 1 0 BRCA2, oligonucleotide/oligosaccharide-binding, domain 1 Rep-A_N PF04057.12 CBZ27750.1 - 0.084 12.9 0.1 1.1 9.3 0.1 2.2 2 0 0 2 2 2 0 Replication factor-A protein 1, N-terminal domain Mannosidase_ig PF17786.1 CBZ27750.1 - 0.12 13.0 0.4 0.26 11.9 0.4 1.5 1 0 0 1 1 1 0 Mannosidase Ig/CBM-like domain Pex14_N PF04695.13 CBZ27750.1 - 5.7 7.6 11.3 1.3 9.7 6.2 2.2 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Steroid_dh PF02544.16 CBZ27751.1 - 1.8e-25 89.6 2.7 3.1e-25 88.9 2.7 1.4 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase DUF1295 PF06966.12 CBZ27751.1 - 2.7e-05 23.8 1.2 4.5e-05 23.1 0.9 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF1295) ubiquitin PF00240.23 CBZ27751.1 - 0.15 11.8 0.0 7 6.5 0.0 2.2 2 0 0 2 2 2 0 Ubiquitin family Dala_Dala_lig_C PF07478.13 CBZ27752.1 - 1.5e-14 54.0 0.0 2.9e-14 53.1 0.0 1.4 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus SET PF00856.28 CBZ27752.1 - 7.3e-07 29.7 0.2 6.9e-06 26.6 0.0 2.7 3 0 0 3 3 3 1 SET domain ATP-grasp_3 PF02655.14 CBZ27752.1 - 1.8e-05 24.9 0.0 6.7e-05 23.0 0.0 1.9 1 1 0 1 1 1 1 ATP-grasp domain ATP-grasp PF02222.22 CBZ27752.1 - 0.0014 18.2 0.0 0.0029 17.2 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain RimK PF08443.11 CBZ27752.1 - 0.011 15.4 0.0 0.02 14.5 0.0 1.4 1 0 0 1 1 1 0 RimK-like ATP-grasp domain ATP-grasp_4 PF13535.6 CBZ27752.1 - 0.043 13.4 0.0 0.076 12.6 0.0 1.4 1 0 0 1 1 1 0 ATP-grasp domain GARS_A PF01071.19 CBZ27752.1 - 0.12 12.2 0.0 0.25 11.1 0.0 1.5 1 0 0 1 1 1 0 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain CHAP PF05257.16 CBZ27753.1 - 1.7e-05 25.3 0.1 3.3e-05 24.4 0.1 1.5 1 0 0 1 1 1 1 CHAP domain Nuc_deoxyri_tr2 PF15891.5 CBZ27753.1 - 0.031 14.6 0.2 0.058 13.7 0.2 1.4 1 0 0 1 1 1 0 Nucleoside 2-deoxyribosyltransferase like MRAP PF15183.6 CBZ27753.1 - 0.051 13.5 0.0 0.19 11.7 0.0 1.9 1 0 0 1 1 1 0 Melanocortin-2 receptor accessory protein family DUF3367 PF11847.8 CBZ27753.1 - 0.16 9.8 0.0 0.2 9.5 0.0 1.1 1 0 0 1 1 1 0 Alpha-(1->3)-arabinofuranosyltransferase zinc_ribbon_16 PF17034.5 CBZ27754.1 - 9e-06 25.9 10.9 0.04 14.1 0.1 2.4 2 0 0 2 2 2 2 Zinc-ribbon like family Zn_ribbon_17 PF17120.5 CBZ27754.1 - 0.49 10.1 21.7 0.014 15.0 13.6 2.5 3 0 0 3 3 3 0 Zinc-ribbon, C4HC2 type Thioredoxin PF00085.20 CBZ27755.1 - 0.0057 16.6 0.1 0.01 15.8 0.1 1.4 1 0 0 1 1 1 1 Thioredoxin DUF4542 PF15075.6 CBZ27756.1 - 0.013 15.9 0.2 0.052 13.9 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4542) SLBP_RNA_bind PF15247.6 CBZ27757.1 - 6.6e-23 80.6 4.2 1.5e-22 79.5 4.2 1.6 1 0 0 1 1 1 1 Histone RNA hairpin-binding protein RNA-binding domain Not3 PF04065.15 CBZ27758.1 - 7.1e-62 208.9 24.0 7.1e-62 208.9 24.0 1.6 2 0 0 2 2 2 1 Not1 N-terminal domain, CCR4-Not complex component NOT2_3_5 PF04153.18 CBZ27758.1 - 5.2e-34 117.1 9.4 5.2e-34 117.1 9.4 2.4 2 0 0 2 2 2 1 NOT2 / NOT3 / NOT5 family Syntaxin_2 PF14523.6 CBZ27758.1 - 0.00033 21.0 0.9 0.00033 21.0 0.9 2.6 2 1 0 2 2 2 1 Syntaxin-like protein WD40 PF00400.32 CBZ27759.1 - 2.8e-19 69.1 9.4 0.0024 18.7 0.0 6.5 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBZ27759.1 - 1.4e-07 31.7 0.1 0.12 12.7 0.0 4.2 2 1 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain TPM_phosphatase PF04536.14 CBZ27760.1 - 1.9e-18 66.8 0.0 2.9e-18 66.2 0.0 1.3 1 0 0 1 1 1 1 TPM domain zf-IS66 PF13005.7 CBZ27760.1 - 0.5 10.8 0.0 0.5 10.8 0.0 3.3 3 0 0 3 3 3 0 zinc-finger binding domain of transposase IS66 SOAR PF16533.5 CBZ27761.1 - 0.2 11.6 2.8 7.9 6.5 0.2 2.9 3 0 0 3 3 3 0 STIM1 Orai1-activating region Vps55 PF04133.14 CBZ27762.1 - 3.1e-24 85.2 5.6 3.7e-24 84.9 5.6 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting 55 Phage_holin_3_6 PF07332.11 CBZ27762.1 - 0.75 9.9 11.3 2.1 8.4 0.8 2.2 2 0 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III PAC3 PF10178.9 CBZ27763.1 - 0.001 19.2 0.0 0.0019 18.3 0.0 1.4 1 0 0 1 1 1 1 Proteasome assembly chaperone 3 DFP PF04127.15 CBZ27764.1 - 3.8e-20 72.5 0.0 1.1e-09 38.3 0.0 2.3 2 0 0 2 2 2 2 DNA / pantothenate metabolism flavoprotein TubC_N PF18563.1 CBZ27764.1 - 0.12 12.4 0.0 0.33 11.0 0.0 1.7 1 0 0 1 1 1 0 TubC N-terminal docking domain DNA_repr_REX1B PF14966.6 CBZ27765.1 - 0.00041 21.0 2.8 0.019 15.6 0.5 2.4 2 0 0 2 2 2 2 DNA repair REX1-B Baculo_p24 PF05073.12 CBZ27765.1 - 0.018 14.8 0.1 0.028 14.2 0.1 1.3 1 0 0 1 1 1 0 Baculovirus P24 capsid protein Virul_Fac PF10139.9 CBZ27765.1 - 0.052 11.8 0.3 0.068 11.4 0.3 1.1 1 0 0 1 1 1 0 Putative bacterial virulence factor TPR_12 PF13424.6 CBZ27766.1 - 7.2e-10 39.0 25.0 8.1e-05 22.8 3.2 4.7 1 1 6 7 7 7 4 Tetratricopeptide repeat TPR_MalT PF17874.1 CBZ27766.1 - 5.1e-08 32.7 3.9 5.1e-08 32.7 3.9 2.1 1 1 1 2 2 2 2 MalT-like TPR region TPR_7 PF13176.6 CBZ27766.1 - 2.2e-06 27.3 14.9 0.0011 18.8 0.4 5.4 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_8 PF13181.6 CBZ27766.1 - 0.037 14.2 8.1 3.7 8.0 0.0 5.4 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_1 PF00515.28 CBZ27766.1 - 0.079 12.8 0.0 0.079 12.8 0.0 4.9 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_2 PF07719.17 CBZ27766.1 - 0.27 11.4 0.1 0.27 11.4 0.1 6.8 6 1 1 7 7 7 0 Tetratricopeptide repeat TPR_10 PF13374.6 CBZ27766.1 - 0.46 10.4 15.9 0.41 10.6 0.1 5.3 5 1 1 6 6 6 0 Tetratricopeptide repeat ANAPC5 PF12862.7 CBZ27766.1 - 3.2 7.9 11.8 1 9.4 0.3 3.5 2 2 1 3 3 3 0 Anaphase-promoting complex subunit 5 TPR_14 PF13428.6 CBZ27766.1 - 4 8.5 31.0 1.8 9.6 0.1 6.8 5 2 2 7 7 7 0 Tetratricopeptide repeat RRM_1 PF00076.22 CBZ27767.1 - 0.11 12.3 0.0 0.19 11.6 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Kinesin PF00225.23 CBZ27769.1 - 1.6e-78 263.9 0.1 1.6e-78 263.9 0.1 1.9 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 CBZ27769.1 - 5.1e-22 78.4 0.2 1.5e-21 76.9 0.0 1.8 2 0 0 2 2 2 1 Microtubule binding FapA PF03961.13 CBZ27769.1 - 0.1 11.2 8.9 0.009 14.7 4.2 1.6 2 0 0 2 2 2 0 Flagellar Assembly Protein A DUF3693 PF12472.8 CBZ27769.1 - 0.16 11.6 1.5 2.7 7.7 0.0 2.8 2 0 0 2 2 2 0 Phage related protein ResIII PF04851.15 CBZ27769.1 - 0.34 10.9 1.9 0.51 10.3 0.1 2.1 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit PIN_8 PF18476.1 CBZ27769.1 - 2.6 7.8 11.4 5.8 6.7 7.1 2.5 2 1 0 2 2 2 0 PIN like domain AAA_16 PF13191.6 CBZ27769.1 - 2.8 8.3 7.1 6.7 7.1 0.0 4.0 3 1 0 3 3 3 0 AAA ATPase domain DUF2203 PF09969.9 CBZ27769.1 - 8.8 7.1 10.6 32 5.3 3.9 2.8 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) Acylphosphatase PF00708.18 CBZ27770.1 - 4.4e-23 81.5 0.0 6.8e-23 80.9 0.0 1.2 1 0 0 1 1 1 1 Acylphosphatase Kinesin PF00225.23 CBZ27771.1 - 6.5e-101 337.6 0.0 1e-100 336.9 0.0 1.3 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 CBZ27771.1 - 5.9e-26 91.2 0.0 1.2e-24 86.9 0.0 2.6 2 0 0 2 2 2 1 Microtubule binding DUF812 PF05667.11 CBZ27771.1 - 0.12 11.3 26.3 0.022 13.7 9.7 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF812) AAA_7 PF12775.7 CBZ27771.1 - 0.14 11.7 0.0 0.3 10.6 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_22 PF13401.6 CBZ27771.1 - 0.28 11.5 0.0 0.28 11.5 0.0 3.3 4 1 0 4 4 4 0 AAA domain DUF5398 PF17376.2 CBZ27771.1 - 2.2 9.0 5.2 13 6.4 0.6 3.6 2 1 0 2 2 2 0 Family of unknown function (DUF5398) SlyX PF04102.12 CBZ27771.1 - 2.9 8.6 26.3 0.26 12.0 0.5 7.0 7 1 0 7 7 7 0 SlyX Pkinase PF00069.25 CBZ27773.1 - 1.9e-56 191.4 0.0 4.4e-41 141.0 0.0 2.5 3 0 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ27773.1 - 1.2e-32 113.3 0.0 7.9e-24 84.3 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 CBZ27773.1 - 2.5e-05 23.2 0.0 4e-05 22.6 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 CBZ27773.1 - 0.00044 19.7 0.0 0.075 12.3 0.0 2.2 2 0 0 2 2 2 2 Kinase-like Kdo PF06293.14 CBZ27773.1 - 0.0068 15.8 0.0 0.01 15.2 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 CBZ27773.1 - 0.012 15.5 0.0 0.022 14.7 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family RIO1 PF01163.22 CBZ27773.1 - 0.041 13.5 0.0 0.065 12.8 0.0 1.2 1 0 0 1 1 1 0 RIO1 family Iso_dh PF00180.20 CBZ27773.1 - 0.19 10.9 0.0 0.31 10.2 0.0 1.2 1 0 0 1 1 1 0 Isocitrate/isopropylmalate dehydrogenase HpcH_HpaI PF03328.14 CBZ27775.1 - 8e-55 185.4 0.0 9.4e-55 185.1 0.0 1.0 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family DHQS PF01959.16 CBZ27775.1 - 0.055 12.4 0.0 0.085 11.8 0.0 1.2 1 0 0 1 1 1 0 3-dehydroquinate synthase II Zeta_toxin PF06414.12 CBZ27776.1 - 0.00011 21.5 0.0 0.41 9.9 0.0 2.3 1 1 1 2 2 2 2 Zeta toxin Rad17 PF03215.15 CBZ27776.1 - 0.0013 18.7 0.1 0.0021 18.0 0.1 1.3 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_16 PF13191.6 CBZ27776.1 - 0.0019 18.6 0.0 0.0052 17.2 0.0 1.8 1 1 0 1 1 1 1 AAA ATPase domain Cytidylate_kin PF02224.18 CBZ27776.1 - 0.0026 17.5 0.1 0.022 14.5 0.0 2.2 2 0 0 2 2 2 1 Cytidylate kinase SRP54 PF00448.22 CBZ27776.1 - 0.015 14.9 0.3 0.13 11.9 0.2 2.2 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain Ribosomal_S7 PF00177.21 CBZ27776.1 - 0.046 13.4 0.0 0.32 10.6 0.0 2.1 2 0 0 2 2 2 0 Ribosomal protein S7p/S5e DUF1456 PF07308.13 CBZ27776.1 - 0.047 14.0 1.2 1.4 9.3 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF1456) AAA_18 PF13238.6 CBZ27776.1 - 0.064 13.8 0.1 0.18 12.3 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.6 CBZ27776.1 - 0.073 13.5 0.0 0.18 12.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain Ploopntkinase2 PF18747.1 CBZ27776.1 - 0.077 12.2 0.0 0.17 11.1 0.0 1.6 2 0 0 2 2 2 0 P-loop Nucleotide Kinase2 AAA_22 PF13401.6 CBZ27776.1 - 0.12 12.6 0.0 0.26 11.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain NIF PF03031.18 CBZ27777.1 - 8.1e-49 165.4 0.1 1.2e-48 164.8 0.1 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase G-alpha PF00503.20 CBZ27777.1 - 0.062 12.5 0.0 0.087 12.0 0.0 1.2 1 0 0 1 1 1 0 G-protein alpha subunit Peptidase_M50 PF02163.22 CBZ27778.1 - 0.15 11.3 0.0 0.24 10.6 0.0 1.2 1 0 0 1 1 1 0 Peptidase family M50 SNF2_N PF00176.23 CBZ27779.1 - 2.9e-39 134.8 0.2 5.1e-39 134.0 0.2 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 CBZ27779.1 - 4.4e-17 62.4 0.0 9.1e-17 61.4 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 CBZ27779.1 - 8.6e-07 29.1 0.0 1.4e-06 28.4 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit PHD PF00628.29 CBZ27779.1 - 2e-06 27.6 13.5 0.0044 16.9 3.5 2.6 2 0 0 2 2 2 2 PHD-finger zf-PHD-like PF15446.6 CBZ27779.1 - 0.016 14.8 7.8 0.1 12.2 1.0 2.6 2 0 0 2 2 2 0 PHD/FYVE-zinc-finger like domain SWI2_SNF2 PF18766.1 CBZ27779.1 - 0.022 14.4 0.0 0.04 13.6 0.0 1.4 1 0 0 1 1 1 0 SWI2/SNF2 ATPase HDA2-3 PF11496.8 CBZ27779.1 - 0.025 13.7 0.0 0.053 12.7 0.0 1.5 1 1 0 1 1 1 0 Class II histone deacetylase complex subunits 2 and 3 ATF7IP_BD PF16788.5 CBZ27779.1 - 0.62 10.1 3.7 1.3 9.1 3.7 1.4 1 0 0 1 1 1 0 ATF-interacting protein binding domain Zf_RING PF16744.5 CBZ27779.1 - 1.7 8.8 7.4 1.3 9.2 1.6 2.6 2 0 0 2 2 2 0 KIAA1045 RING finger GET2 PF08690.10 CBZ27779.1 - 9.2 5.8 6.1 33 4.0 3.4 2.1 2 0 0 2 2 2 0 GET complex subunit GET2 SpoIIE PF07228.12 CBZ27780.1 - 5.6e-16 59.0 0.1 7.6e-15 55.3 0.1 2.0 1 1 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) PP2C_2 PF13672.6 CBZ27780.1 - 1.1e-05 25.2 0.1 2.4e-05 24.1 0.1 1.5 1 1 0 1 1 1 1 Protein phosphatase 2C PP2C PF00481.21 CBZ27780.1 - 0.00027 20.7 0.1 0.0027 17.4 0.0 2.1 2 0 0 2 2 2 1 Protein phosphatase 2C Rieske PF00355.26 CBZ27781.1 - 7.9e-07 28.9 0.3 1.7e-06 27.9 0.3 1.5 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Rieske_2 PF13806.6 CBZ27781.1 - 2.3e-06 27.5 0.0 4.1e-06 26.7 0.0 1.4 1 0 0 1 1 1 1 Rieske-like [2Fe-2S] domain NAD_binding_1 PF00175.21 CBZ27781.1 - 0.0018 18.9 0.0 0.28 11.8 0.0 2.5 2 0 0 2 2 2 2 Oxidoreductase NAD-binding domain GTP_EFTU PF00009.27 CBZ27782.1 - 5e-51 173.0 0.0 7.9e-51 172.4 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.24 CBZ27782.1 - 3e-16 59.2 0.0 8.5e-16 57.8 0.0 1.8 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_IV PF03764.18 CBZ27782.1 - 3.8e-07 29.9 0.0 8.8e-07 28.7 0.0 1.5 1 0 0 1 1 1 1 Elongation factor G, domain IV GTP_EFTU_D2 PF03144.25 CBZ27782.1 - 5.1e-07 30.0 0.0 1.3e-06 28.7 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_II PF14492.6 CBZ27782.1 - 0.00045 20.3 0.0 0.0023 18.0 0.0 2.1 2 0 0 2 2 2 1 Elongation Factor G, domain II cobW PF02492.19 CBZ27782.1 - 0.05 13.2 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain Ras PF00071.22 CBZ27782.1 - 0.082 12.5 0.1 0.15 11.7 0.1 1.3 1 0 0 1 1 1 0 Ras family RsgA_GTPase PF03193.16 CBZ27782.1 - 0.085 12.8 0.3 0.21 11.5 0.3 1.6 1 0 0 1 1 1 0 RsgA GTPase SRPRB PF09439.10 CBZ27782.1 - 0.14 11.6 0.0 0.26 10.7 0.0 1.4 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit mRNA_triPase PF02940.15 CBZ27784.1 - 9.8e-11 41.8 0.0 2.3e-10 40.6 0.0 1.7 2 1 0 2 2 2 1 mRNA capping enzyme, beta chain TPR_2 PF07719.17 CBZ27785.1 - 1.3e-15 56.1 24.9 0.0086 16.1 0.1 7.1 6 1 1 7 7 7 6 Tetratricopeptide repeat TPR_1 PF00515.28 CBZ27785.1 - 8.8e-12 44.3 18.0 0.001 18.8 0.1 7.0 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_16 PF13432.6 CBZ27785.1 - 5.4e-09 36.6 23.0 0.0035 18.0 0.5 4.6 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_8 PF13181.6 CBZ27785.1 - 2.9e-08 33.3 19.8 0.0082 16.3 0.1 6.8 6 1 1 7 7 7 2 Tetratricopeptide repeat TPR_14 PF13428.6 CBZ27785.1 - 5.9e-07 29.8 13.4 0.047 14.5 0.2 5.7 3 1 2 5 5 5 2 Tetratricopeptide repeat TPR_12 PF13424.6 CBZ27785.1 - 4e-06 27.0 19.4 0.0057 16.9 1.6 4.8 3 2 1 4 4 4 3 Tetratricopeptide repeat TPR_11 PF13414.6 CBZ27785.1 - 5.8e-06 25.9 14.8 0.55 10.0 1.1 6.7 6 1 1 7 7 7 2 TPR repeat zf-C2H2_10 PF16588.5 CBZ27785.1 - 4.3e-05 23.1 2.2 0.00011 21.9 2.2 1.7 1 0 0 1 1 1 1 C2H2 zinc-finger TPR_19 PF14559.6 CBZ27785.1 - 0.00047 20.6 9.8 1.8 9.1 0.0 4.8 2 2 2 4 4 4 1 Tetratricopeptide repeat zf-CCHC PF00098.23 CBZ27785.1 - 0.0035 17.3 1.3 0.0067 16.5 1.3 1.5 1 0 0 1 1 1 1 Zinc knuckle TPR_6 PF13174.6 CBZ27785.1 - 0.0059 17.2 9.3 3.9 8.3 0.0 5.3 5 1 0 5 5 4 1 Tetratricopeptide repeat zf-CCHC_2 PF13696.6 CBZ27785.1 - 0.017 14.9 0.4 0.028 14.2 0.4 1.3 1 0 0 1 1 1 0 Zinc knuckle ANAPC3 PF12895.7 CBZ27785.1 - 0.044 14.0 11.3 2.1 8.6 1.4 4.3 2 2 2 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 Fis1_TPR_C PF14853.6 CBZ27785.1 - 0.05 13.7 3.4 12 6.0 0.0 3.5 3 1 0 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat Filo_VP35 PF02097.15 CBZ27785.1 - 0.085 11.9 0.2 0.15 11.1 0.2 1.4 1 0 0 1 1 1 0 Filoviridae VP35 MIT PF04212.18 CBZ27785.1 - 0.26 11.4 11.0 2.7 8.1 0.5 4.0 3 0 0 3 3 3 0 MIT (microtubule interacting and transport) domain TPR_17 PF13431.6 CBZ27785.1 - 0.3 11.5 7.0 6.9 7.3 0.0 5.0 6 0 0 6 6 4 0 Tetratricopeptide repeat TPR_3 PF07720.12 CBZ27785.1 - 1.3 9.1 6.5 8 6.6 0.1 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_9 PF13371.6 CBZ27785.1 - 4.2 7.6 8.2 3.5 7.9 0.3 4.1 3 1 2 5 5 5 0 Tetratricopeptide repeat KBP_C PF12309.8 CBZ27786.1 - 2.9e-46 158.6 3.9 3e-45 155.3 0.7 3.0 2 1 0 2 2 2 1 KIF-1 binding protein C terminal NRN1 PF15056.6 CBZ27786.1 - 0.057 13.5 0.2 0.16 12.1 0.2 1.7 1 0 0 1 1 1 0 Neuritin protein family TPR_7 PF13176.6 CBZ27786.1 - 0.43 10.7 3.5 8.4 6.7 0.2 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat eIF3_subunit PF08597.10 CBZ27787.1 - 2.7e-08 34.0 12.5 4.2e-08 33.4 12.5 1.4 1 1 0 1 1 1 1 Translation initiation factor eIF3 subunit CoA_binding PF02629.19 CBZ27788.1 - 1.4e-27 96.2 4.0 1.6e-27 96.0 2.4 1.9 2 0 0 2 2 2 1 CoA binding domain Ligase_CoA PF00549.19 CBZ27788.1 - 3.8e-23 82.0 0.7 6e-23 81.4 0.1 1.6 2 0 0 2 2 2 1 CoA-ligase Succ_CoA_lig PF13607.6 CBZ27788.1 - 3.3e-09 36.7 0.0 6.7e-09 35.7 0.0 1.5 1 0 0 1 1 1 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.6 CBZ27788.1 - 0.00075 20.0 0.1 0.0015 19.0 0.1 1.5 1 0 0 1 1 1 1 CoA binding domain CoA_binding PF02629.19 CBZ27789.1 - 1.4e-27 96.2 4.0 1.6e-27 96.0 2.4 1.9 2 0 0 2 2 2 1 CoA binding domain Ligase_CoA PF00549.19 CBZ27789.1 - 3.8e-23 82.0 0.7 6e-23 81.4 0.1 1.6 2 0 0 2 2 2 1 CoA-ligase Succ_CoA_lig PF13607.6 CBZ27789.1 - 3.3e-09 36.7 0.0 6.7e-09 35.7 0.0 1.5 1 0 0 1 1 1 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.6 CBZ27789.1 - 0.00075 20.0 0.1 0.0015 19.0 0.1 1.5 1 0 0 1 1 1 1 CoA binding domain BRO1 PF03097.18 CBZ27790.1 - 8.7e-23 80.7 0.0 1.1e-22 80.4 0.0 1.0 1 0 0 1 1 1 1 BRO1-like domain KIX PF02172.16 CBZ27790.1 - 0.068 13.4 0.0 0.18 12.1 0.0 1.7 1 0 0 1 1 1 0 KIX domain Exonuc_VII_L PF02601.15 CBZ27791.1 - 0.0051 16.4 1.8 0.0065 16.1 1.8 1.1 1 0 0 1 1 1 1 Exonuclease VII, large subunit UPF0449 PF15136.6 CBZ27791.1 - 0.024 15.1 0.4 0.048 14.1 0.4 1.6 1 0 0 1 1 1 0 Uncharacterised protein family UPF0449 Rad60-SLD PF11976.8 CBZ27792.1 - 0.00018 21.2 0.1 0.00031 20.5 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 CBZ27792.1 - 0.00057 19.6 0.0 0.001 18.8 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family CLP1_P PF16575.5 CBZ27793.1 - 2e-17 63.6 0.0 3.7e-17 62.7 0.0 1.4 1 0 0 1 1 1 1 mRNA cleavage and polyadenylation factor CLP1 P-loop CLP1_N PF16573.5 CBZ27793.1 - 7.5e-07 29.3 0.0 1.2e-06 28.6 0.0 1.4 1 0 0 1 1 1 1 N-terminal beta-sandwich domain of polyadenylation factor Glyco_tranf_2_5 PF13712.6 CBZ27793.1 - 0.24 11.1 0.0 0.37 10.4 0.0 1.2 1 0 0 1 1 1 0 Glycosyltransferase like family Sec1 PF00995.23 CBZ27794.1 - 2.2e-86 291.3 0.0 2.7e-86 291.1 0.0 1.0 1 0 0 1 1 1 1 Sec1 family ATP-synt_F PF01990.17 CBZ27794.1 - 0.0082 16.4 0.1 0.81 10.0 0.0 3.3 3 0 0 3 3 3 1 ATP synthase (F/14-kDa) subunit H2O2_YaaD PF03883.14 CBZ27794.1 - 0.012 15.1 0.1 0.02 14.4 0.1 1.2 1 0 0 1 1 1 0 Peroxide stress protein YaaA DUF2730 PF10805.8 CBZ27794.1 - 0.11 12.7 0.1 0.26 11.4 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2730) DnaJ PF00226.31 CBZ27795.1 - 2.9e-23 81.8 2.3 5.9e-23 80.8 2.3 1.6 1 0 0 1 1 1 1 DnaJ domain zf-C2H2_jaz PF12171.8 CBZ27795.1 - 7.6e-10 38.8 6.2 1.5e-09 37.9 6.2 1.5 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 CBZ27795.1 - 9.1e-08 32.3 3.3 1.7e-07 31.4 3.3 1.5 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.7 CBZ27795.1 - 7.1e-05 23.1 0.5 0.0002 21.6 0.1 1.9 2 0 0 2 2 2 1 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.6 CBZ27795.1 - 0.011 16.5 1.4 0.03 15.2 0.5 2.2 2 0 0 2 2 2 0 C2H2-type zinc finger DUF4136 PF13590.6 CBZ27795.1 - 0.024 15.2 3.7 0.05 14.2 3.7 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4136) AKAP95 PF04988.12 CBZ27795.1 - 0.031 14.5 0.4 0.031 14.5 0.4 1.8 2 0 0 2 2 2 0 A-kinase anchoring protein 95 (AKAP95) zf-C2H2 PF00096.26 CBZ27795.1 - 0.055 13.9 1.5 0.12 12.9 1.5 1.6 1 0 0 1 1 1 0 Zinc finger, C2H2 type zf-C2H2_6 PF13912.6 CBZ27795.1 - 0.18 11.9 1.1 0.4 10.7 1.1 1.7 1 0 0 1 1 1 0 C2H2-type zinc finger ParcG PF10274.9 CBZ27796.1 - 5.8e-78 261.2 0.0 6.9e-78 261.0 0.0 1.1 1 0 0 1 1 1 1 Parkin co-regulated protein DCB PF16213.5 CBZ27796.1 - 0.11 12.1 0.0 0.17 11.6 0.0 1.2 1 0 0 1 1 1 0 Dimerisation and cyclophilin-binding domain of Mon2 Totivirus_coat PF05518.11 CBZ27796.1 - 2.7 5.9 4.3 3.3 5.7 4.3 1.0 1 0 0 1 1 1 0 Totivirus coat protein PCI PF01399.27 CBZ27797.1 - 4e-06 27.3 0.1 1.3e-05 25.6 0.0 1.9 2 0 0 2 2 2 1 PCI domain TPR_1 PF00515.28 CBZ27797.1 - 0.0012 18.6 2.4 0.091 12.6 0.1 4.3 5 0 0 5 5 5 1 Tetratricopeptide repeat SHNi-TPR PF10516.9 CBZ27797.1 - 0.095 12.2 0.5 0.26 10.8 0.5 1.7 1 0 0 1 1 1 0 SHNi-TPR TPR_2 PF07719.17 CBZ27797.1 - 0.17 12.1 9.9 2.3 8.5 0.2 5.5 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_14 PF13428.6 CBZ27797.1 - 0.19 12.7 15.7 10 7.3 0.2 5.5 4 1 1 5 5 5 0 Tetratricopeptide repeat TPR_11 PF13414.6 CBZ27797.1 - 0.3 10.8 3.0 3.1 7.6 0.2 3.0 4 0 0 4 4 4 0 TPR repeat TPR_9 PF13371.6 CBZ27797.1 - 0.93 9.7 7.2 4.7 7.4 0.8 3.6 3 1 0 3 3 3 0 Tetratricopeptide repeat Gp-FAR-1 PF05823.12 CBZ27798.1 - 0.046 14.1 0.7 0.13 12.6 0.3 1.9 1 1 0 1 1 1 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) PrmC_N PF17827.1 CBZ27798.1 - 0.066 13.8 0.1 1.1 9.9 0.1 2.9 2 0 0 2 2 2 0 PrmC N-terminal domain Fib_alpha PF08702.10 CBZ27798.1 - 0.33 11.1 8.1 0.32 11.2 1.7 2.5 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family SOAR PF16533.5 CBZ27798.1 - 0.46 10.5 6.1 2.9 7.9 0.9 2.9 2 0 0 2 2 2 0 STIM1 Orai1-activating region Cytochrom_B562 PF07361.11 CBZ27798.1 - 0.91 10.2 5.3 0.35 11.5 1.3 2.4 2 0 0 2 2 2 0 Cytochrome b562 DUF913 PF06025.12 CBZ27798.1 - 1 8.3 0.0 1 8.3 0.0 2.9 3 1 1 4 4 4 0 Domain of Unknown Function (DUF913) DUF1664 PF07889.12 CBZ27798.1 - 4.7 7.3 6.5 21 5.2 5.4 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) Pex2_Pex12 PF04757.14 CBZ27799.1 - 6e-28 98.0 12.1 7.5e-28 97.7 12.1 1.1 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4 PF00097.25 CBZ27799.1 - 0.021 14.7 12.1 0.033 14.1 12.1 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 CBZ27799.1 - 0.036 14.2 9.3 0.081 13.1 9.4 1.5 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.6 CBZ27799.1 - 0.13 12.2 13.5 0.19 11.6 13.5 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) TFIIS_C PF01096.18 CBZ27799.1 - 0.27 11.1 5.8 0.64 9.9 5.8 1.6 1 0 0 1 1 1 0 Transcription factor S-II (TFIIS) zf-RING_5 PF14634.6 CBZ27799.1 - 0.55 10.2 12.0 0.89 9.6 12.0 1.3 1 0 0 1 1 1 0 zinc-RING finger domain zf-RING_UBOX PF13445.6 CBZ27799.1 - 0.56 10.3 9.0 1.1 9.4 9.0 1.5 1 0 0 1 1 1 0 RING-type zinc-finger zf-C3HC4_2 PF13923.6 CBZ27799.1 - 0.82 9.6 7.1 1.8 8.4 7.1 1.6 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CBZ27799.1 - 1.2 9.5 10.2 2.2 8.7 10.2 1.4 1 0 0 1 1 1 0 Ring finger domain PHD PF00628.29 CBZ27800.1 - 2.3e-05 24.2 7.9 2.3e-05 24.2 7.9 3.0 3 0 0 3 3 3 2 PHD-finger zf-PHD-like PF15446.6 CBZ27800.1 - 0.017 14.7 0.7 0.017 14.7 0.7 2.8 3 0 0 3 3 3 0 PHD/FYVE-zinc-finger like domain DHHC PF01529.20 CBZ27805.1 - 2.5e-36 124.7 3.3 2.5e-36 124.7 3.3 2.0 2 0 0 2 2 2 1 DHHC palmitoyltransferase LptF_LptG PF03739.14 CBZ27805.1 - 0.03 13.2 1.5 1.2 7.9 0.6 2.3 2 0 0 2 2 2 0 Lipopolysaccharide export system permease LptF/LptG Yip1 PF04893.17 CBZ27805.1 - 0.033 13.9 0.7 0.033 13.9 0.7 2.2 2 0 0 2 2 2 0 Yip1 domain DUF975 PF06161.11 CBZ27805.1 - 0.061 13.1 0.3 0.061 13.1 0.3 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF975) Neur_chan_memb PF02932.16 CBZ27805.1 - 2.6 8.0 8.9 0.53 10.3 5.1 1.7 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region Pex2_Pex12 PF04757.14 CBZ27806.1 - 6.3e-14 52.1 0.3 3.7e-11 43.1 0.3 2.1 1 1 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4_3 PF13920.6 CBZ27806.1 - 1.1e-09 38.0 7.1 1.6e-09 37.5 7.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CBZ27806.1 - 1.8e-09 37.8 9.3 3.1e-09 37.0 9.3 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 CBZ27806.1 - 1.6e-08 34.4 6.8 2.7e-08 33.7 6.8 1.3 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 CBZ27806.1 - 2.9e-07 30.3 7.6 4.6e-07 29.6 7.6 1.3 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.25 CBZ27806.1 - 8.9e-07 28.7 8.0 1.5e-06 28.0 8.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 CBZ27806.1 - 1.7e-06 28.1 8.1 3.1e-06 27.2 8.1 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.7 CBZ27806.1 - 1.7e-05 25.0 6.1 3.1e-05 24.2 6.1 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 CBZ27806.1 - 1.9e-05 24.6 3.2 3.1e-05 23.9 3.2 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.6 CBZ27806.1 - 5.1e-05 23.2 5.4 0.00022 21.2 5.5 2.0 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 CBZ27806.1 - 5.8e-05 22.9 8.3 0.0001 22.1 8.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) DUF4381 PF14316.6 CBZ27806.1 - 0.044 14.0 0.1 0.19 12.0 0.0 2.0 2 1 0 2 2 2 0 Domain of unknown function (DUF4381) zf-Di19 PF05605.12 CBZ27806.1 - 0.051 13.9 1.1 0.37 11.1 0.2 2.2 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding Zn_ribbon_17 PF17120.5 CBZ27806.1 - 0.097 12.3 5.9 0.21 11.2 5.9 1.6 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-Nse PF11789.8 CBZ27806.1 - 0.11 12.4 2.4 0.25 11.2 2.4 1.6 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit TerY_C PF15616.6 CBZ27806.1 - 0.13 12.4 1.0 0.21 11.7 1.0 1.3 1 0 0 1 1 1 0 TerY-C metal binding domain Rtf2 PF04641.12 CBZ27806.1 - 0.14 11.5 0.4 0.25 10.7 0.2 1.4 1 1 0 1 1 1 0 Rtf2 RING-finger zf-RING_10 PF16685.5 CBZ27806.1 - 0.19 11.9 3.3 0.35 11.0 3.3 1.4 1 0 0 1 1 1 0 zinc RING finger of MSL2 zf-RING_6 PF14835.6 CBZ27806.1 - 0.23 11.3 3.9 0.96 9.4 3.1 2.1 2 0 0 2 2 2 0 zf-RING of BARD1-type protein zf-RING_4 PF14570.6 CBZ27806.1 - 0.63 9.9 8.1 1.4 8.8 8.1 1.5 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-C2HC5 PF06221.13 CBZ27806.1 - 1.8 8.7 6.1 0.48 10.5 2.7 1.8 1 1 0 1 1 1 0 Putative zinc finger motif, C2HC5-type FANCL_C PF11793.8 CBZ27806.1 - 2.4 8.4 7.3 17 5.6 7.3 2.3 1 1 0 1 1 1 0 FANCL C-terminal domain IBR PF01485.21 CBZ27806.1 - 4.8 7.5 8.4 4.1 7.7 6.4 1.9 1 1 1 2 2 2 0 IBR domain, a half RING-finger domain LRR_4 PF12799.7 CBZ27807.1 - 1.3e-07 31.8 5.0 2.6e-05 24.5 0.8 3.1 1 1 2 3 3 3 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CBZ27807.1 - 2.7e-06 27.1 1.2 8.7e-06 25.4 1.2 1.9 1 0 0 1 1 1 1 Leucine rich repeat EF-hand_7 PF13499.6 CBZ27807.1 - 3.6e-06 27.3 0.2 2.2e-05 24.8 0.0 2.4 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.32 CBZ27807.1 - 0.00011 21.5 0.0 0.0049 16.3 0.0 3.0 2 0 0 2 2 2 1 EF hand LRR_6 PF13516.6 CBZ27807.1 - 0.0002 21.2 0.2 0.78 9.9 0.0 2.9 2 0 0 2 2 2 2 Leucine Rich repeat EF-hand_6 PF13405.6 CBZ27807.1 - 0.0025 17.6 0.0 0.021 14.7 0.0 2.5 2 0 0 2 2 2 1 EF-hand domain 7TMR-HDED PF07697.11 CBZ27807.1 - 0.029 14.5 0.8 0.28 11.3 0.8 2.4 1 1 0 1 1 1 0 7TM-HD extracellular EF-hand_8 PF13833.6 CBZ27807.1 - 0.032 14.1 0.2 1.5 8.7 0.0 2.8 1 1 1 2 2 2 0 EF-hand domain pair LRR_1 PF00560.33 CBZ27807.1 - 0.037 14.6 3.1 3.6 8.5 0.1 3.2 2 0 0 2 2 2 0 Leucine Rich Repeat REV1_C PF16727.5 CBZ27807.1 - 0.05 14.0 0.8 0.19 12.1 0.2 2.3 2 0 0 2 2 2 0 DNA repair protein REV1 C-terminal domain DUF4352 PF11611.8 CBZ27808.1 - 0.063 13.6 0.0 0.12 12.7 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4352) SPC12 PF06645.13 CBZ27809.1 - 4.2e-07 30.0 0.6 6.2e-07 29.4 0.6 1.3 1 0 0 1 1 1 1 Microsomal signal peptidase 12 kDa subunit (SPC12) Nucleo_LEF-12 PF06256.11 CBZ27809.1 - 0.018 14.8 0.1 0.024 14.4 0.1 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus LEF-12 protein COX14 PF14880.6 CBZ27809.1 - 0.16 11.8 0.8 0.57 10.1 0.7 1.9 1 1 0 1 1 1 0 Cytochrome oxidase c assembly Sensor PF13796.6 CBZ27809.1 - 0.55 10.3 7.3 1.1 9.3 7.3 1.4 1 1 0 1 1 1 0 Putative sensor VPS9 PF02204.18 CBZ27810.1 - 3e-15 56.3 0.0 4.7e-15 55.7 0.0 1.3 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain MORN PF02493.20 CBZ27810.1 - 4.7e-08 32.5 22.1 1e-05 25.1 1.3 6.0 6 0 0 6 6 6 3 MORN repeat Pkinase PF00069.25 CBZ27811.1 - 1.1e-66 224.9 0.0 1.4e-66 224.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ27811.1 - 2.1e-38 132.1 0.0 2.8e-38 131.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CBZ27811.1 - 2.7e-05 23.6 0.0 4.9e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 CBZ27811.1 - 0.0059 16.6 0.0 0.17 11.8 0.0 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 CBZ27811.1 - 0.065 12.6 0.0 0.12 11.7 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family CHAD PF05235.14 CBZ27812.1 - 6.1e-05 23.1 4.4 0.00015 21.8 4.4 1.6 1 1 0 1 1 1 1 CHAD domain TPR_4 PF07721.14 CBZ27812.1 - 1.9 9.4 5.4 0.92 10.3 1.6 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat Utp13 PF08625.11 CBZ27813.1 - 0.039 13.9 0.5 0.34 10.8 0.0 2.6 3 0 0 3 3 3 0 Utp13 specific WD40 associated domain ADK PF00406.22 CBZ27814.1 - 1.9e-34 119.0 0.0 2.2e-34 118.7 0.0 1.0 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 CBZ27814.1 - 7.6e-16 58.8 0.0 1.3e-15 58.0 0.0 1.3 1 0 0 1 1 1 1 AAA domain ADK_lid PF05191.14 CBZ27814.1 - 1.3e-10 41.0 2.3 2.1e-10 40.4 2.3 1.3 1 0 0 1 1 1 1 Adenylate kinase, active site lid A2L_zn_ribbon PF08792.10 CBZ27814.1 - 0.0017 18.0 0.9 0.35 10.6 0.0 2.4 2 0 0 2 2 2 2 A2L zinc ribbon domain AAA_18 PF13238.6 CBZ27814.1 - 0.051 14.1 0.0 0.077 13.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 CBZ27814.1 - 0.074 13.2 0.0 0.1 12.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain YadA_anchor PF03895.15 CBZ27814.1 - 0.082 13.0 0.1 0.16 12.1 0.1 1.3 1 0 0 1 1 1 0 YadA-like membrane anchor domain zf-C2H2_3 PF13878.6 CBZ27814.1 - 0.19 11.6 1.8 0.23 11.3 0.0 1.9 2 0 0 2 2 2 0 zinc-finger of acetyl-transferase ESCO DUF2627 PF11118.8 CBZ27815.1 - 0.084 13.5 0.2 0.13 12.9 0.2 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2627) GSP_synth PF03738.14 CBZ27816.1 - 6e-43 147.5 0.0 2.3e-35 122.5 0.0 2.1 2 0 0 2 2 2 2 Glutathionylspermidine synthase preATP-grasp CHAP PF05257.16 CBZ27816.1 - 4.5e-13 49.6 0.0 1.2e-12 48.3 0.0 1.7 1 0 0 1 1 1 1 CHAP domain Arv1 PF04161.13 CBZ27817.1 - 1.2e-32 113.8 5.7 1.7e-32 113.3 5.7 1.2 1 0 0 1 1 1 1 Arv1-like family PH_12 PF16457.5 CBZ27818.1 - 4.7e-06 27.2 0.0 0.00021 21.8 0.0 3.5 3 0 0 3 3 3 1 Pleckstrin homology domain CENP-T_C PF15511.6 CBZ27822.1 - 1e-06 28.8 0.1 1.5e-06 28.3 0.1 1.3 1 1 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CBFD_NFYB_HMF PF00808.23 CBZ27822.1 - 9.5e-05 22.6 0.8 0.00011 22.5 0.1 1.4 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TAF PF02969.17 CBZ27822.1 - 0.0002 21.5 0.2 0.00032 20.8 0.2 1.3 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) Bromo_TP PF07524.13 CBZ27822.1 - 0.00061 19.7 0.0 0.00077 19.4 0.0 1.2 1 0 0 1 1 1 1 Bromodomain associated Histone PF00125.24 CBZ27822.1 - 0.0034 17.7 2.2 0.0064 16.9 2.2 1.5 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID-31kDa PF02291.15 CBZ27822.1 - 0.011 15.8 0.0 0.014 15.4 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit PCP_red PF08369.10 CBZ27822.1 - 0.18 12.0 1.6 0.46 10.7 0.1 2.3 2 1 0 2 2 2 0 Proto-chlorophyllide reductase 57 kD subunit Galactosyl_T PF01762.21 CBZ27823.1 - 0.00048 20.0 0.2 0.0015 18.4 0.0 1.9 2 0 0 2 2 2 1 Galactosyltransferase Lysyl_oxidase PF01186.17 CBZ27823.1 - 0.057 13.1 0.2 0.1 12.3 0.2 1.3 1 0 0 1 1 1 0 Lysyl oxidase LSM PF01423.22 CBZ27824.1 - 7e-13 48.1 0.2 1.3e-12 47.2 0.2 1.5 1 1 0 1 1 1 1 LSM domain AbrB_C PF18277.1 CBZ27824.1 - 0.15 11.7 0.2 3.7 7.3 0.0 2.8 3 0 0 3 3 3 0 AbrB C-terminal domain Brix PF04427.18 CBZ27825.1 - 6.7e-29 101.4 0.0 8.7e-29 101.0 0.0 1.1 1 0 0 1 1 1 1 Brix domain Glyoxalase_4 PF13669.6 CBZ27826.1 - 5.6e-17 62.0 0.0 6.7e-17 61.7 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_3 PF13468.6 CBZ27826.1 - 0.00088 19.4 0.0 0.001 19.2 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase PF00903.25 CBZ27826.1 - 0.0028 17.9 0.0 0.0032 17.7 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily GDC-P PF02347.16 CBZ27827.1 - 6.8e-169 562.2 0.0 6.4e-155 516.2 0.0 3.1 3 0 0 3 3 3 3 Glycine cleavage system P-protein Beta_elim_lyase PF01212.21 CBZ27827.1 - 0.0044 16.3 0.2 0.011 15.0 0.0 1.6 2 0 0 2 2 2 1 Beta-eliminating lyase Cys_Met_Meta_PP PF01053.20 CBZ27827.1 - 0.026 13.1 0.0 0.32 9.5 0.0 2.1 2 0 0 2 2 2 0 Cys/Met metabolism PLP-dependent enzyme Pkinase PF00069.25 CBZ27828.1 - 4.7e-57 193.3 0.0 5.3e-57 193.2 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ27828.1 - 4.8e-23 81.8 0.0 5e-23 81.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CBZ27828.1 - 0.0029 17.0 0.0 0.0081 15.5 0.0 1.7 2 0 0 2 2 2 1 Kinase-like FTA2 PF13095.6 CBZ27828.1 - 0.018 14.6 0.0 0.026 14.1 0.0 1.2 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 Rhomboid PF01694.22 CBZ27834.1 - 0.0005 20.1 1.9 0.0012 18.8 1.9 1.7 1 1 0 1 1 1 1 Rhomboid family Rhomboid PF01694.22 CBZ27835.1 - 0.0005 20.1 1.9 0.0012 18.8 1.9 1.7 1 1 0 1 1 1 1 Rhomboid family Pribosyltran PF00156.27 CBZ27836.1 - 7e-17 61.4 0.0 9.7e-17 60.9 0.0 1.2 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.6 CBZ27836.1 - 4e-05 23.2 0.0 5.3e-05 22.8 0.0 1.2 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase PRTase_2 PF15609.6 CBZ27836.1 - 0.074 12.5 0.0 0.15 11.6 0.0 1.5 2 0 0 2 2 2 0 Phosphoribosyl transferase MCM_bind PF09739.9 CBZ27837.1 - 1.8e-35 122.5 0.0 7.2e-35 120.5 0.0 1.8 1 1 0 1 1 1 1 Mini-chromosome maintenance replisome factor NIF PF03031.18 CBZ27838.1 - 1.6e-50 170.9 0.9 2.3e-50 170.4 0.3 1.5 2 0 0 2 2 2 1 NLI interacting factor-like phosphatase zf_PR_Knuckle PF18445.1 CBZ27838.1 - 0.032 14.0 0.0 0.084 12.7 0.0 1.7 1 0 0 1 1 1 0 PR zinc knuckle motif Ribosomal_L30 PF00327.20 CBZ27839.1 - 5.8e-19 67.7 2.8 1.4e-18 66.5 2.8 1.7 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e Ribosomal_L30_N PF08079.12 CBZ27839.1 - 4.9e-16 58.7 14.2 9e-16 57.9 14.2 1.4 1 0 0 1 1 1 1 Ribosomal L30 N-terminal domain Ribosomal_L30 PF00327.20 CBZ27840.1 - 7.6e-19 67.3 2.8 1.7e-18 66.2 2.8 1.7 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e Ribosomal_L30_N PF08079.12 CBZ27840.1 - 6.3e-16 58.4 14.2 1.2e-15 57.5 14.2 1.5 1 0 0 1 1 1 1 Ribosomal L30 N-terminal domain DUF2062 PF09835.9 CBZ27841.1 - 1.6e-06 28.0 6.8 1.9e-06 27.8 6.8 1.0 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2062) DUF1453 PF07301.11 CBZ27841.1 - 0.099 12.6 5.7 0.66 10.0 0.5 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1453) TMEM223 PF14640.6 CBZ27841.1 - 0.65 10.2 3.6 1.1 9.5 0.5 2.1 1 1 1 2 2 2 0 Transmembrane protein 223 NifU PF01106.17 CBZ27842.1 - 7.1e-26 90.1 0.1 2.4e-25 88.5 0.0 2.0 2 0 0 2 2 2 1 NifU-like domain Nfu_N PF08712.11 CBZ27842.1 - 1.3e-21 76.4 0.0 2.3e-21 75.6 0.0 1.3 1 0 0 1 1 1 1 Scaffold protein Nfu/NifU N terminal eRF1_1 PF03463.15 CBZ27843.1 - 2.1e-31 108.6 0.1 7.3e-31 106.8 0.0 1.9 2 0 0 2 2 2 1 eRF1 domain 1 eRF1_2 PF03464.15 CBZ27843.1 - 2.7e-17 63.3 0.2 4.2e-17 62.7 0.2 1.3 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.15 CBZ27843.1 - 2.6e-14 53.7 0.0 8.7e-14 52.0 0.0 1.9 2 0 0 2 2 2 1 eRF1 domain 3 DUF334 PF03904.13 CBZ27843.1 - 0.0056 16.3 0.3 0.0087 15.6 0.3 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF334) SNAPc_SNAP43 PF09808.9 CBZ27843.1 - 0.16 11.9 0.2 0.29 11.0 0.2 1.4 1 0 0 1 1 1 0 Small nuclear RNA activating complex (SNAPc), subunit SNAP43 SIR2 PF02146.17 CBZ27844.1 - 5.8e-57 192.5 0.0 7.9e-57 192.0 0.0 1.2 1 0 0 1 1 1 1 Sir2 family zinc_ribbon_4 PF13717.6 CBZ27844.1 - 0.0042 17.0 1.7 0.015 15.2 0.2 2.4 2 0 0 2 2 2 1 zinc-ribbon domain LIDHydrolase PF10230.9 CBZ27845.1 - 6.1e-61 206.3 0.0 7.1e-61 206.1 0.0 1.0 1 0 0 1 1 1 1 Lipid-droplet associated hydrolase Hydrolase_4 PF12146.8 CBZ27845.1 - 4.5e-11 42.5 0.0 5.5e-11 42.2 0.0 1.1 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 CBZ27845.1 - 5.1e-05 24.0 0.3 6.8e-05 23.6 0.3 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 CBZ27845.1 - 0.00067 19.4 0.1 0.0013 18.4 0.1 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Thioesterase PF00975.20 CBZ27845.1 - 0.0023 18.1 0.1 0.0041 17.3 0.1 1.4 1 0 0 1 1 1 1 Thioesterase domain Nodulin-like PF06813.13 CBZ27845.1 - 0.023 14.2 0.2 0.036 13.5 0.2 1.2 1 0 0 1 1 1 0 Nodulin-like DUF1057 PF06342.12 CBZ27845.1 - 0.026 13.6 0.0 0.034 13.2 0.0 1.1 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1057) PGAP1 PF07819.13 CBZ27845.1 - 0.032 14.0 0.0 0.061 13.0 0.0 1.4 1 0 0 1 1 1 0 PGAP1-like protein IF4E PF01652.18 CBZ27847.1 - 1.3e-12 47.7 0.0 1.6e-12 47.5 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E MMR_HSR1 PF01926.23 CBZ27850.1 - 4.5e-44 149.2 0.1 4.8e-21 75.0 0.0 2.4 2 0 0 2 2 2 2 50S ribosome-binding GTPase GTP_EFTU PF00009.27 CBZ27850.1 - 3.7e-25 88.6 1.0 3.1e-12 46.4 0.0 4.0 2 2 0 2 2 2 2 Elongation factor Tu GTP binding domain FeoB_N PF02421.18 CBZ27850.1 - 4.7e-20 71.7 0.1 6.8e-09 35.4 0.0 2.3 2 0 0 2 2 2 2 Ferrous iron transport protein B Dynamin_N PF00350.23 CBZ27850.1 - 2.6e-16 60.1 0.2 0.00074 19.6 0.0 4.2 3 1 1 4 4 4 3 Dynamin family AIG1 PF04548.16 CBZ27850.1 - 5.8e-15 55.2 0.0 1e-06 28.3 0.0 2.6 2 0 0 2 2 2 2 AIG1 family Roc PF08477.13 CBZ27850.1 - 1.3e-13 51.2 0.0 4.6e-06 26.8 0.0 3.1 2 1 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase KH_dom-like PF14714.6 CBZ27850.1 - 1.4e-12 47.7 0.3 3.1e-12 46.6 0.3 1.6 1 0 0 1 1 1 1 KH-domain-like of EngA bacterial GTPase enzymes, C-terminal SRPRB PF09439.10 CBZ27850.1 - 5e-12 45.6 0.0 2.1e-05 24.1 0.0 2.4 2 0 0 2 2 2 2 Signal recognition particle receptor beta subunit RsgA_GTPase PF03193.16 CBZ27850.1 - 7.7e-12 45.4 0.6 0.027 14.4 0.0 4.3 2 1 2 4 4 4 3 RsgA GTPase Ras PF00071.22 CBZ27850.1 - 1.3e-10 41.1 0.1 2.1e-06 27.4 0.1 2.7 2 1 0 2 2 2 2 Ras family MMR_HSR1_Xtn PF16897.5 CBZ27850.1 - 8.2e-06 25.8 0.0 0.072 13.1 0.0 2.5 2 0 0 2 2 2 2 C-terminal region of MMR_HSR1 domain Septin PF00735.18 CBZ27850.1 - 1.1e-05 24.9 0.0 0.009 15.3 0.0 2.4 2 0 0 2 2 2 2 Septin ABC_tran PF00005.27 CBZ27850.1 - 1.6e-05 25.4 0.0 0.28 11.7 0.0 2.4 2 0 0 2 2 2 2 ABC transporter cobW PF02492.19 CBZ27850.1 - 7.7e-05 22.3 0.6 0.33 10.5 0.2 3.7 3 1 1 4 4 4 1 CobW/HypB/UreG, nucleotide-binding domain PduV-EutP PF10662.9 CBZ27850.1 - 0.00013 21.7 0.0 0.94 9.2 0.0 3.6 3 1 0 3 3 3 1 Ethanolamine utilisation - propanediol utilisation Arf PF00025.21 CBZ27850.1 - 0.00014 21.4 0.7 0.1 12.0 0.1 3.3 2 2 0 2 2 2 1 ADP-ribosylation factor family TniB PF05621.11 CBZ27850.1 - 0.00015 21.3 0.0 0.022 14.2 0.0 3.1 3 0 0 3 3 3 1 Bacterial TniB protein IIGP PF05049.13 CBZ27850.1 - 0.0014 17.8 0.1 0.26 10.3 0.1 2.6 2 1 0 2 2 2 1 Interferon-inducible GTPase (IIGP) GBP PF02263.19 CBZ27850.1 - 0.0052 16.1 0.0 2.6 7.2 0.0 2.3 2 0 0 2 2 2 2 Guanylate-binding protein, N-terminal domain MobB PF03205.14 CBZ27850.1 - 0.0089 15.9 0.0 0.17 11.8 0.0 2.4 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B T2SSE PF00437.20 CBZ27850.1 - 0.021 13.9 0.0 0.053 12.6 0.0 1.8 1 1 0 1 1 1 0 Type II/IV secretion system protein AAA_18 PF13238.6 CBZ27850.1 - 0.024 15.2 0.0 0.87 10.1 0.0 2.5 2 0 0 2 2 2 0 AAA domain ATPase_2 PF01637.18 CBZ27850.1 - 0.031 14.2 0.0 1.5 8.7 0.0 2.6 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea AAA_29 PF13555.6 CBZ27850.1 - 0.033 13.9 0.0 6.8 6.5 0.0 2.4 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_21 PF13304.6 CBZ27850.1 - 0.037 13.8 0.0 3.9 7.2 0.0 2.8 3 0 0 3 3 3 0 AAA domain, putative AbiEii toxin, Type IV TA system FtsK_SpoIIIE PF01580.18 CBZ27850.1 - 0.052 12.9 0.0 1.6 8.0 0.0 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family G-alpha PF00503.20 CBZ27850.1 - 0.062 12.4 0.0 4 6.5 0.0 2.8 3 0 0 3 3 3 0 G-protein alpha subunit AAA_23 PF13476.6 CBZ27850.1 - 0.07 13.6 0.0 19 5.7 0.0 2.5 2 0 0 2 2 2 0 AAA domain CLP1_P PF16575.5 CBZ27850.1 - 0.074 12.8 0.7 31 4.3 0.0 3.4 2 1 1 3 3 3 0 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_22 PF13401.6 CBZ27850.1 - 0.076 13.3 0.0 6.3 7.1 0.0 3.2 4 0 0 4 4 3 0 AAA domain AAA_16 PF13191.6 CBZ27850.1 - 0.14 12.6 0.1 27 5.1 0.0 3.3 3 1 0 3 3 3 0 AAA ATPase domain AAA_15 PF13175.6 CBZ27850.1 - 0.19 11.4 0.0 13 5.4 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain Ank_3 PF13606.6 CBZ27851.1 - 0.011 16.2 0.0 12 6.9 0.0 2.9 3 0 0 3 3 3 0 Ankyrin repeat NUDIX_2 PF13869.6 CBZ27852.1 - 1.2e-40 139.1 0.0 1.3e-39 135.8 0.0 2.4 1 1 0 1 1 1 1 Nucleotide hydrolase Peptidase_M1 PF01433.20 CBZ27853.1 - 6.5e-75 251.4 1.1 1.6e-74 250.2 0.2 1.9 2 0 0 2 2 2 1 Peptidase family M1 domain ERAP1_C PF11838.8 CBZ27853.1 - 1.6e-51 175.8 0.1 2.7e-51 175.0 0.1 1.3 1 0 0 1 1 1 1 ERAP1-like C-terminal domain Peptidase_M1_N PF17900.1 CBZ27853.1 - 1.5e-38 132.9 0.0 4.8e-38 131.2 0.0 1.8 2 0 0 2 2 2 1 Peptidase M1 N-terminal domain DUF4774 PF15999.5 CBZ27853.1 - 0.15 11.9 1.1 0.44 10.4 1.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4774) Peptidase_M61 PF05299.12 CBZ27853.1 - 2.3 8.7 4.5 44 4.5 0.0 3.5 3 1 0 3 3 3 0 M61 glycyl aminopeptidase 6PF2K PF01591.18 CBZ27854.1 - 1.2e-32 113.0 0.0 1.8e-32 112.5 0.0 1.2 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.22 CBZ27854.1 - 2.1e-15 57.0 0.0 1.5e-08 34.6 0.0 2.5 1 1 1 2 2 2 2 Histidine phosphatase superfamily (branch 1) Ank_5 PF13857.6 CBZ27854.1 - 5.3e-12 45.7 0.1 1.6e-11 44.2 0.1 1.8 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 CBZ27854.1 - 7.3e-12 45.7 0.0 4.8e-11 43.1 0.0 2.3 2 1 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CBZ27854.1 - 1.5e-09 38.2 0.0 4.1e-07 30.4 0.0 2.7 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 CBZ27854.1 - 5.4e-08 32.9 0.3 6.3e-05 23.2 0.1 3.6 3 0 0 3 3 3 1 Ankyrin repeat Ank_3 PF13606.6 CBZ27854.1 - 7.5e-08 32.1 0.1 7.5e-06 25.9 0.0 3.8 4 0 0 4 4 4 1 Ankyrin repeat AAA_33 PF13671.6 CBZ27854.1 - 2.7e-06 27.6 0.2 5.3e-06 26.6 0.2 1.5 1 0 0 1 1 1 1 AAA domain KTI12 PF08433.10 CBZ27854.1 - 0.00016 21.2 0.1 0.00036 20.1 0.1 1.5 1 1 0 1 1 1 1 Chromatin associated protein KTI12 AAA_5 PF07728.14 CBZ27854.1 - 0.019 14.9 0.1 0.098 12.7 0.1 2.2 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_19 PF13245.6 CBZ27854.1 - 0.045 14.1 0.1 0.2 12.0 0.0 2.0 2 0 0 2 2 2 0 AAA domain THF_DHG_CYH_C PF02882.19 CBZ27855.1 - 6.6e-61 204.3 0.4 1.1e-60 203.5 0.4 1.4 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.23 CBZ27855.1 - 8.6e-37 126.0 0.4 1.2e-36 125.5 0.4 1.2 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain Cyclin_N PF00134.23 CBZ27856.1 - 1.3e-14 54.0 0.7 6.7e-14 51.7 0.0 2.3 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 CBZ27856.1 - 0.00016 21.7 1.9 0.00093 19.3 0.9 2.5 1 1 1 2 2 2 1 Cyclin, C-terminal domain IU_nuc_hydro PF01156.19 CBZ27857.1 - 2.3e-18 66.8 2.4 3.6e-18 66.2 2.4 1.3 1 1 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase Aminotran_MocR PF12897.7 CBZ27857.1 - 0.036 12.9 0.0 0.061 12.1 0.0 1.2 1 0 0 1 1 1 0 Alanine-glyoxylate amino-transferase FGGY_C PF02782.16 CBZ27857.1 - 0.053 13.2 0.2 0.21 11.3 0.2 2.0 1 1 0 1 1 1 0 FGGY family of carbohydrate kinases, C-terminal domain Vps52 PF04129.12 CBZ27858.1 - 3.6e-50 171.2 0.2 2.6e-17 62.8 0.0 3.5 3 1 0 3 3 3 3 Vps52 / Sac2 family DASH_Duo1 PF08651.10 CBZ27858.1 - 0.001 18.8 0.4 0.4 10.5 0.2 2.7 3 0 0 3 3 3 2 DASH complex subunit Duo1 PUMA PF15826.5 CBZ27858.1 - 0.092 12.9 4.8 0.17 12.0 4.8 1.3 1 0 0 1 1 1 0 Bcl-2-binding component 3, p53 upregulated modulator of apoptosis TPR_2 PF07719.17 CBZ27860.1 - 4.9e-30 101.2 32.4 0.0011 18.9 0.0 15.0 16 1 0 16 16 15 6 Tetratricopeptide repeat TPR_1 PF00515.28 CBZ27860.1 - 6.7e-22 76.3 21.9 0.00018 21.1 0.0 11.2 14 0 0 14 14 12 5 Tetratricopeptide repeat TPR_8 PF13181.6 CBZ27860.1 - 1.3e-18 65.6 15.9 0.001 19.1 0.0 12.2 15 0 0 15 15 14 4 Tetratricopeptide repeat TPR_9 PF13371.6 CBZ27860.1 - 4.2e-17 62.1 43.0 0.071 13.3 0.5 11.0 6 2 5 11 11 11 7 Tetratricopeptide repeat TPR_12 PF13424.6 CBZ27860.1 - 1.6e-15 57.1 49.3 0.00024 21.3 3.6 11.6 10 2 2 12 12 11 6 Tetratricopeptide repeat TPR_16 PF13432.6 CBZ27860.1 - 3.1e-15 56.5 57.8 6.6e-05 23.5 4.1 11.4 7 3 5 12 12 12 6 Tetratricopeptide repeat TPR_11 PF13414.6 CBZ27860.1 - 2e-09 36.9 15.7 0.014 15.0 0.0 8.1 11 0 0 11 11 10 2 TPR repeat TPR_19 PF14559.6 CBZ27860.1 - 7.3e-06 26.4 28.0 0.0013 19.2 0.0 7.7 9 1 1 10 10 7 3 Tetratricopeptide repeat TPR_14 PF13428.6 CBZ27860.1 - 9.4e-06 26.0 43.8 0.87 10.6 0.0 11.1 11 1 2 13 13 10 3 Tetratricopeptide repeat TPR_17 PF13431.6 CBZ27860.1 - 3e-05 24.1 14.5 7.6 7.2 0.0 7.5 8 0 0 8 8 7 2 Tetratricopeptide repeat NARP1 PF12569.8 CBZ27860.1 - 0.00011 21.3 0.0 0.9 8.4 0.0 3.5 4 0 0 4 4 4 2 NMDA receptor-regulated protein 1 ANAPC5 PF12862.7 CBZ27860.1 - 0.0044 17.0 6.6 11 6.1 0.0 6.4 4 2 2 7 7 7 0 Anaphase-promoting complex subunit 5 TPR_15 PF13429.6 CBZ27860.1 - 0.0077 15.5 4.4 12 5.0 0.2 4.9 4 1 1 5 5 5 0 Tetratricopeptide repeat SHNi-TPR PF10516.9 CBZ27860.1 - 0.017 14.6 1.8 0.94 9.0 0.0 4.6 5 0 0 5 5 5 0 SHNi-TPR ANAPC3 PF12895.7 CBZ27860.1 - 0.023 14.9 18.8 4 7.7 0.1 7.5 5 2 3 8 8 8 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.6 CBZ27860.1 - 0.024 15.3 25.4 44 5.0 0.0 10.3 13 0 0 13 13 11 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 CBZ27860.1 - 0.057 13.5 8.2 1.2 9.3 0.0 5.3 6 0 0 6 6 5 0 Fis1 C-terminal tetratricopeptide repeat TPR_20 PF14561.6 CBZ27860.1 - 0.27 11.6 11.0 13 6.2 0.1 6.0 5 1 1 6 6 6 0 Tetratricopeptide repeat TPR_10 PF13374.6 CBZ27860.1 - 0.97 9.4 41.8 8 6.5 0.1 10.9 13 0 0 13 13 11 0 Tetratricopeptide repeat TPR_7 PF13176.6 CBZ27860.1 - 3.8 7.8 32.0 3.9 7.7 0.1 10.2 13 0 0 13 13 12 0 Tetratricopeptide repeat Ist1 PF03398.14 CBZ27861.1 - 6.5e-45 153.0 0.1 8e-45 152.7 0.1 1.1 1 0 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway Ret2_MD PF18528.1 CBZ27862.1 - 1.4e-48 163.2 0.5 2.8e-48 162.2 0.5 1.5 1 0 0 1 1 1 1 RNA editing 3' terminal uridylyl transferase 2 middle domain PAP_assoc PF03828.19 CBZ27862.1 - 8.1e-16 58.0 0.1 1.6e-15 57.0 0.1 1.5 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.23 CBZ27862.1 - 7.1e-05 23.0 0.0 0.00012 22.2 0.0 1.4 1 0 0 1 1 1 1 Nucleotidyltransferase domain DUF2967 PF11179.8 CBZ27862.1 - 0.082 11.0 1.0 0.33 9.0 1.0 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF2967) Polbeta PF18765.1 CBZ27862.1 - 0.19 11.9 0.0 0.37 10.9 0.0 1.5 1 0 0 1 1 1 0 Polymerase beta, Nucleotidyltransferase 2OG-FeII_Oxy_2 PF13532.6 CBZ27863.1 - 7.2e-12 45.9 0.0 1.2e-11 45.1 0.0 1.4 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DUF1091 PF06477.13 CBZ27864.1 - 0.012 16.0 0.0 0.016 15.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1091) DUF3090 PF11290.8 CBZ27864.1 - 0.086 12.6 1.4 0.18 11.6 0.1 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3090) zf-B_box PF00643.24 CBZ27864.1 - 0.56 10.4 11.4 1.1 9.4 5.9 2.9 3 0 0 3 3 3 0 B-box zinc finger PyrI_C PF02748.15 CBZ27864.1 - 0.74 9.8 10.0 5.6 6.9 0.1 3.3 3 1 0 3 3 3 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain Sgf11 PF08209.11 CBZ27864.1 - 1 9.0 11.0 0.85 9.2 0.6 2.8 2 0 0 2 2 2 0 Sgf11 (transcriptional regulation protein) PseudoU_synth_1 PF01416.20 CBZ27865.1 - 0.00028 21.3 0.0 0.021 15.3 0.0 2.7 2 0 0 2 2 2 2 tRNA pseudouridine synthase ParA PF10609.9 CBZ27866.1 - 5.1e-93 311.0 0.2 6.4e-92 307.5 0.2 1.9 1 1 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 CBZ27866.1 - 9.7e-10 38.6 0.0 3.6e-09 36.7 0.0 1.9 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.6 CBZ27866.1 - 2.8e-07 30.6 0.2 2.9e-05 24.1 0.1 2.2 2 0 0 2 2 2 1 AAA domain ArsA_ATPase PF02374.15 CBZ27866.1 - 7.1e-07 28.7 0.2 6.3e-06 25.6 0.1 2.2 3 0 0 3 3 3 1 Anion-transporting ATPase MipZ PF09140.11 CBZ27866.1 - 0.00012 21.4 0.1 0.0016 17.8 0.2 2.0 2 0 0 2 2 2 1 ATPase MipZ AAA_25 PF13481.6 CBZ27866.1 - 0.00019 21.1 0.1 0.00041 20.0 0.1 1.5 1 0 0 1 1 1 1 AAA domain Fer4_NifH PF00142.18 CBZ27866.1 - 0.0052 16.3 0.1 0.012 15.0 0.0 1.6 2 0 0 2 2 2 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family NACHT PF05729.12 CBZ27866.1 - 0.008 16.1 0.2 0.014 15.4 0.2 1.3 1 0 0 1 1 1 1 NACHT domain NB-ARC PF00931.22 CBZ27866.1 - 0.024 13.8 0.2 0.048 12.8 0.2 1.4 1 0 0 1 1 1 0 NB-ARC domain CLP1_P PF16575.5 CBZ27866.1 - 0.045 13.5 0.0 2.9 7.6 0.0 2.6 3 0 0 3 3 3 0 mRNA cleavage and polyadenylation factor CLP1 P-loop APS_kinase PF01583.20 CBZ27866.1 - 0.061 13.2 0.1 0.11 12.4 0.1 1.3 1 0 0 1 1 1 0 Adenylylsulphate kinase Hpr_kinase_C PF07475.12 CBZ27866.1 - 0.062 12.8 0.1 0.28 10.7 0.2 1.9 2 0 0 2 2 2 0 HPr Serine kinase C-terminal domain CBP_BcsQ PF06564.12 CBZ27866.1 - 0.12 11.8 0.2 0.33 10.4 0.2 1.7 1 1 0 1 1 1 0 Cellulose biosynthesis protein BcsQ RsgA_GTPase PF03193.16 CBZ27866.1 - 0.13 12.2 0.1 0.3 11.0 0.1 1.6 1 0 0 1 1 1 0 RsgA GTPase RNA_helicase PF00910.22 CBZ27866.1 - 0.18 12.2 0.0 0.39 11.1 0.0 1.5 1 0 0 1 1 1 0 RNA helicase DUF1358 PF07096.11 CBZ27867.1 - 0.00051 20.0 0.0 0.0014 18.6 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF1358) DUF2730 PF10805.8 CBZ27867.1 - 0.16 12.1 0.0 20 5.3 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2730) DUF5345 PF17280.2 CBZ27867.1 - 5.4 7.1 4.9 16 5.6 1.1 2.6 2 0 0 2 2 2 0 Family of unknown function (DUF5345) ATP-synt_C PF00137.21 CBZ27869.1 - 1.8e-07 31.4 14.2 1.8e-07 31.4 14.2 1.6 2 0 0 2 2 2 1 ATP synthase subunit C DUF2474 PF10617.9 CBZ27870.1 - 0.036 13.9 0.4 0.12 12.3 0.4 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2474) GGDEF_2 PF17853.1 CBZ27870.1 - 0.048 13.9 12.2 3.5 7.9 0.3 5.0 5 0 0 5 5 5 0 GGDEF-like domain Adaptin_N PF01602.20 CBZ27870.1 - 0.076 11.6 0.0 0.98 7.9 0.0 2.2 2 0 0 2 2 2 0 Adaptin N terminal region TetR_C_20 PF17925.1 CBZ27870.1 - 1.5 9.2 7.3 0.55 10.6 0.3 3.8 4 0 0 4 4 4 0 Tetracyclin repressor-like, C-terminal domain ATP_bind_1 PF03029.17 CBZ27871.1 - 1.5e-48 165.7 0.0 1.6e-46 159.1 0.0 2.2 1 1 1 2 2 2 2 Conserved hypothetical ATP binding protein AAA_22 PF13401.6 CBZ27871.1 - 0.0057 16.9 0.0 0.14 12.4 0.0 2.6 3 1 0 3 3 3 1 AAA domain AAA_18 PF13238.6 CBZ27871.1 - 0.012 16.2 2.6 0.13 12.8 0.1 3.1 2 1 0 2 2 2 0 AAA domain AAA_33 PF13671.6 CBZ27871.1 - 0.018 15.2 0.0 0.051 13.7 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.6 CBZ27871.1 - 0.023 15.1 1.2 0.44 11.0 0.3 2.7 3 0 0 3 3 3 0 AAA domain AAA PF00004.29 CBZ27871.1 - 0.072 13.5 0.1 0.5 10.8 0.0 2.3 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) PAP_assoc PF03828.19 CBZ27872.1 - 3.3e-07 30.4 0.1 6.6e-07 29.4 0.1 1.5 1 0 0 1 1 1 1 Cid1 family poly A polymerase MdcG PF10620.9 CBZ27872.1 - 0.0049 16.7 0.8 0.25 11.1 0.1 2.5 1 1 1 2 2 2 2 Phosphoribosyl-dephospho-CoA transferase MdcG NTP_transf_2 PF01909.23 CBZ27872.1 - 0.045 14.0 0.0 0.087 13.1 0.0 1.5 1 1 0 1 1 1 0 Nucleotidyltransferase domain LRR_6 PF13516.6 CBZ27873.1 - 2e-35 117.8 19.9 0.00032 20.5 0.0 12.1 12 0 0 12 12 12 10 Leucine Rich repeat LRR_4 PF12799.7 CBZ27873.1 - 4.5e-08 33.3 13.3 0.041 14.3 0.1 5.9 5 2 1 6 6 6 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 CBZ27873.1 - 4.4e-06 26.5 5.5 16 6.5 0.0 7.9 10 0 0 10 10 10 2 Leucine Rich Repeat LRR_8 PF13855.6 CBZ27873.1 - 0.052 13.3 23.4 1.3 8.8 1.1 7.5 4 2 4 8 8 8 0 Leucine rich repeat MAPKK1_Int PF08923.10 CBZ27877.1 - 0.0012 18.6 0.0 0.038 13.8 0.0 2.0 2 0 0 2 2 2 2 Mitogen-activated protein kinase kinase 1 interacting DUF525 PF04379.14 CBZ27878.1 - 3.4e-15 56.1 0.0 1e-14 54.5 0.0 1.7 1 0 0 1 1 1 1 ApaG domain Taxilin PF09728.9 CBZ27880.1 - 2e-10 40.3 40.9 2.7e-10 39.9 40.9 1.2 1 0 0 1 1 1 1 Myosin-like coiled-coil protein BRE1 PF08647.11 CBZ27880.1 - 0.0041 17.2 6.3 0.0041 17.2 6.3 4.2 1 1 1 3 3 3 1 BRE1 E3 ubiquitin ligase Fib_alpha PF08702.10 CBZ27880.1 - 0.022 14.9 24.2 0.52 10.5 6.2 2.9 1 1 0 2 2 2 0 Fibrinogen alpha/beta chain family Tropomyosin_1 PF12718.7 CBZ27880.1 - 0.39 10.9 44.1 0.24 11.5 13.3 4.0 1 1 1 3 3 3 0 Tropomyosin like ATG16 PF08614.11 CBZ27880.1 - 0.42 10.8 43.5 6.5 6.9 7.2 3.2 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) DUF1664 PF07889.12 CBZ27880.1 - 0.5 10.4 27.1 3.5 7.7 0.9 3.9 1 1 3 4 4 4 0 Protein of unknown function (DUF1664) XhlA PF10779.9 CBZ27880.1 - 0.54 10.5 16.5 14 6.0 0.1 4.5 3 1 0 4 4 4 0 Haemolysin XhlA ZnuA PF01297.17 CBZ27880.1 - 3.9 6.8 7.2 29 4.0 4.5 2.8 1 1 0 1 1 1 0 Zinc-uptake complex component A periplasmic Phage_GP20 PF06810.11 CBZ27880.1 - 4.1 7.2 27.9 4.7 7.0 0.2 4.1 1 1 3 4 4 4 0 Phage minor structural protein GP20 Spc7 PF08317.11 CBZ27880.1 - 4.9 5.9 40.3 3.6 6.4 18.2 3.0 1 1 1 2 2 2 0 Spc7 kinetochore protein DUF2730 PF10805.8 CBZ27880.1 - 5.4 7.2 15.0 0.31 11.1 2.3 3.7 2 1 3 5 5 5 0 Protein of unknown function (DUF2730) GAS PF13851.6 CBZ27880.1 - 8.6 5.6 47.6 2.7 7.3 14.4 4.2 2 1 3 5 5 5 0 Growth-arrest specific micro-tubule binding PPR_2 PF13041.6 CBZ27881.1 - 1.1e-11 44.7 3.4 2.3e-06 27.7 0.0 3.9 2 2 2 4 4 4 4 PPR repeat family PPR_3 PF13812.6 CBZ27881.1 - 6.8e-09 35.7 0.0 0.0005 20.1 0.0 2.9 2 1 0 3 3 3 2 Pentatricopeptide repeat domain PPR PF01535.20 CBZ27881.1 - 1.8e-06 27.8 9.6 0.014 15.6 0.1 5.1 5 1 0 5 5 5 2 PPR repeat PPR_long PF17177.4 CBZ27881.1 - 1.7e-05 24.3 0.1 8.2e-05 22.1 0.1 1.9 1 1 0 1 1 1 1 Pentacotripeptide-repeat region of PRORP TPR_14 PF13428.6 CBZ27881.1 - 0.016 16.0 0.4 32 5.7 0.0 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat Cpn10 PF00166.21 CBZ27882.1 - 2.7e-25 88.2 0.3 3.1e-25 88.1 0.3 1.0 1 0 0 1 1 1 1 Chaperonin 10 Kd subunit Cpn10 PF00166.21 CBZ27884.1 - 2.7e-25 88.2 0.3 3.1e-25 88.1 0.3 1.0 1 0 0 1 1 1 1 Chaperonin 10 Kd subunit DUF4821 PF16092.5 CBZ27885.1 - 9.5e-14 51.7 0.0 3e-13 50.0 0.0 1.8 1 1 0 1 1 1 1 Domain of unknown function (DUF4821) Pyr_redox_2 PF07992.14 CBZ27885.1 - 4.9e-09 35.8 0.0 9.4e-09 34.9 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 CBZ27885.1 - 0.011 16.3 0.0 0.13 12.8 0.0 2.7 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Thioredoxin PF00085.20 CBZ27886.1 - 5.4e-56 186.9 0.0 4.5e-27 94.1 0.0 2.2 2 0 0 2 2 2 2 Thioredoxin ERp29 PF07749.12 CBZ27886.1 - 2.4e-18 66.8 0.1 5e-18 65.8 0.1 1.6 1 0 0 1 1 1 1 Endoplasmic reticulum protein ERp29, C-terminal domain Thioredoxin_2 PF13098.6 CBZ27886.1 - 2.5e-17 63.3 0.3 3.3e-07 30.7 0.0 3.0 2 1 0 2 2 2 2 Thioredoxin-like domain OST3_OST6 PF04756.13 CBZ27886.1 - 1.3e-16 60.8 0.0 7.6e-08 32.0 0.0 2.2 1 1 1 2 2 2 2 OST3 / OST6 family, transporter family Thioredoxin_7 PF13899.6 CBZ27886.1 - 4.1e-09 36.5 0.2 2.2e-05 24.5 0.0 2.7 2 1 0 2 2 2 2 Thioredoxin-like Thioredoxin_8 PF13905.6 CBZ27886.1 - 9.6e-09 35.5 0.0 0.00058 20.1 0.1 3.9 2 2 2 4 4 4 2 Thioredoxin-like AhpC-TSA PF00578.21 CBZ27886.1 - 6.3e-08 32.6 0.0 0.00062 19.7 0.0 2.4 2 0 0 2 2 2 2 AhpC/TSA family TraF PF13728.6 CBZ27886.1 - 1e-07 32.0 0.0 0.013 15.3 0.0 2.3 2 0 0 2 2 2 2 F plasmid transfer operon protein HyaE PF07449.11 CBZ27886.1 - 3.1e-06 27.1 0.0 0.036 14.0 0.0 2.4 2 0 0 2 2 2 2 Hydrogenase-1 expression protein HyaE Redoxin PF08534.10 CBZ27886.1 - 1.3e-05 24.9 0.1 0.0074 16.0 0.1 2.3 2 0 0 2 2 2 2 Redoxin Glutaredoxin PF00462.24 CBZ27886.1 - 0.026 14.8 0.7 0.67 10.2 0.0 2.7 2 0 0 2 2 2 0 Glutaredoxin Thioredoxin_5 PF13743.6 CBZ27886.1 - 0.039 13.6 0.3 4 7.1 0.0 3.4 2 2 2 4 4 4 0 Thioredoxin Thioredoxin_4 PF13462.6 CBZ27886.1 - 1 9.5 3.3 23 5.1 0.0 2.9 3 1 0 3 3 3 0 Thioredoxin Thioredoxin PF00085.20 CBZ27887.1 - 2.9e-17 62.5 0.0 3.9e-17 62.1 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 CBZ27887.1 - 0.0001 22.5 0.2 0.31 11.4 0.0 2.3 1 1 1 2 2 2 2 Thioredoxin-like Thioredoxin_2 PF13098.6 CBZ27887.1 - 0.00016 22.1 0.0 0.00032 21.1 0.0 1.6 1 1 0 1 1 1 1 Thioredoxin-like domain OST3_OST6 PF04756.13 CBZ27887.1 - 0.00023 20.6 0.0 0.00023 20.6 0.0 1.4 2 0 0 2 2 2 1 OST3 / OST6 family, transporter family TraF PF13728.6 CBZ27887.1 - 0.01 15.7 0.0 0.019 14.8 0.0 1.3 1 1 0 1 1 1 1 F plasmid transfer operon protein Thioredoxin_7 PF13899.6 CBZ27887.1 - 0.048 13.8 0.1 0.11 12.7 0.1 1.6 1 1 0 1 1 1 0 Thioredoxin-like AhpC-TSA PF00578.21 CBZ27887.1 - 0.077 12.9 0.0 0.38 10.7 0.0 1.8 2 0 0 2 2 2 0 AhpC/TSA family DUF2012 PF09430.10 CBZ27888.1 - 7.4e-30 103.6 0.1 9.7e-30 103.2 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2012) CarboxypepD_reg PF13620.6 CBZ27888.1 - 0.0069 16.6 0.1 0.018 15.3 0.1 1.8 2 0 0 2 2 2 1 Carboxypeptidase regulatory-like domain SpaA PF17802.1 CBZ27888.1 - 0.026 14.8 0.1 0.063 13.6 0.0 1.7 2 0 0 2 2 2 0 Prealbumin-like fold domain DIM PF08194.12 CBZ27888.1 - 0.04 14.1 0.2 0.097 12.9 0.2 1.6 1 0 0 1 1 1 0 DIM protein SNARE PF05739.19 CBZ27889.1 - 9.7e-09 35.1 0.9 9.7e-09 35.1 0.9 2.3 3 0 0 3 3 3 1 SNARE domain Syntaxin-6_N PF09177.11 CBZ27889.1 - 0.00039 20.9 1.5 0.0044 17.5 0.0 2.4 1 1 1 2 2 2 1 Syntaxin 6, N-terminal CRPA PF05745.11 CBZ27889.1 - 0.0089 16.1 0.7 0.014 15.4 0.1 1.6 2 0 0 2 2 2 1 Chlamydia 15 kDa cysteine-rich outer membrane protein (CRPA) Snapin_Pallidin PF14712.6 CBZ27889.1 - 0.025 15.0 3.8 6.3 7.3 1.1 2.7 2 1 0 2 2 2 0 Snapin/Pallidin Laminin_II PF06009.12 CBZ27889.1 - 0.12 12.3 2.6 0.47 10.5 0.3 2.4 2 1 0 2 2 2 0 Laminin Domain II DUF2951 PF11166.8 CBZ27889.1 - 0.18 12.0 4.7 0.072 13.3 1.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2951) DHR10 PF18595.1 CBZ27889.1 - 0.27 11.3 9.8 0.42 10.7 0.6 2.8 1 1 2 3 3 3 0 Designed helical repeat protein 10 domain EMP24_GP25L PF01105.24 CBZ27889.1 - 0.37 10.7 2.3 0.42 10.5 0.2 2.0 2 0 0 2 2 2 0 emp24/gp25L/p24 family/GOLD T3SSipB PF16535.5 CBZ27889.1 - 0.45 11.0 5.0 1 9.8 0.1 2.3 1 1 0 2 2 2 0 Type III cell invasion protein SipB TBCA PF02970.16 CBZ27889.1 - 0.64 10.4 4.1 0.53 10.7 0.3 2.6 1 1 3 4 4 4 0 Tubulin binding cofactor A Fib_alpha PF08702.10 CBZ27889.1 - 1.5 9.0 6.0 4.6 7.4 1.6 2.2 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Pentapeptide_4 PF13599.6 CBZ27890.1 - 1.3e-10 41.3 8.2 9.3e-07 28.9 0.1 3.0 2 1 2 4 4 4 3 Pentapeptide repeats (9 copies) Pentapeptide PF00805.22 CBZ27890.1 - 1.5e-06 27.7 4.9 1e-05 25.0 0.1 3.8 4 0 0 4 4 4 1 Pentapeptide repeats (8 copies) Pentapeptide_3 PF13576.6 CBZ27890.1 - 3.6e-05 23.8 5.8 0.00028 21.0 0.0 3.8 3 0 0 3 3 3 1 Pentapeptide repeats (9 copies) DAGK_cat PF00781.24 CBZ27891.1 - 6e-13 48.5 0.1 1.6e-11 43.9 0.0 2.5 2 0 0 2 2 2 2 Diacylglycerol kinase catalytic domain RCC1 PF00415.18 CBZ27894.1 - 3e-70 232.6 42.1 1.1e-15 58.0 0.2 12.2 11 2 0 11 11 11 10 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 CBZ27894.1 - 2.4e-40 135.5 75.6 1.2e-07 31.3 2.0 11.8 13 0 0 13 13 13 9 Regulator of chromosome condensation (RCC1) repeat Hira PF07569.11 CBZ27894.1 - 0.02 14.6 0.5 11 5.7 0.0 3.7 4 0 0 4 4 4 0 TUP1-like enhancer of split GAD-like PF08887.11 CBZ27894.1 - 0.034 13.9 1.2 19 5.1 0.0 3.9 4 0 0 4 4 4 0 GAD-like domain Tachylectin PF14517.6 CBZ27894.1 - 0.038 13.5 0.2 0.33 10.5 0.1 2.1 2 0 0 2 2 2 0 Tachylectin MliC PF09864.9 CBZ27894.1 - 0.14 12.1 0.9 14 5.8 0.2 3.1 2 0 0 2 2 2 0 Membrane-bound lysozyme-inhibitor of c-type lysozyme RCC1 PF00415.18 CBZ27895.1 - 2.4e-63 210.5 36.4 2.8e-12 47.0 0.1 12.5 13 0 0 13 13 13 10 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 CBZ27895.1 - 8.5e-36 121.0 58.2 2.1e-05 24.2 0.5 12.5 12 0 0 12 12 12 10 Regulator of chromosome condensation (RCC1) repeat Hira PF07569.11 CBZ27895.1 - 0.002 17.9 0.1 0.31 10.7 0.0 3.3 4 1 0 4 4 4 1 TUP1-like enhancer of split S19 PF06756.11 CBZ27895.1 - 0.016 15.1 0.0 5.8 6.9 0.0 2.7 2 0 0 2 2 2 0 Chorion protein S19 C-terminal RRM_1 PF00076.22 CBZ27896.1 - 6.6e-11 41.9 0.1 1e-10 41.3 0.1 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PUA_3 PF17785.1 CBZ27896.1 - 0.089 12.6 0.3 4.3 7.2 0.0 2.5 1 1 1 2 2 2 0 PUA-like domain RRM_1 PF00076.22 CBZ27898.1 - 6.4e-09 35.5 0.1 1e-07 31.7 0.1 2.1 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) GSHPx PF00255.19 CBZ27900.1 - 1.6e-36 124.1 0.3 2.1e-36 123.8 0.3 1.1 1 0 0 1 1 1 1 Glutathione peroxidase AhpC-TSA PF00578.21 CBZ27900.1 - 0.00029 20.7 0.1 0.0006 19.7 0.0 1.5 2 0 0 2 2 2 1 AhpC/TSA family Redoxin PF08534.10 CBZ27900.1 - 0.055 13.2 0.0 0.099 12.3 0.0 1.4 2 0 0 2 2 2 0 Redoxin GSHPx PF00255.19 CBZ27901.1 - 1.4e-36 124.3 0.3 1.8e-36 124.0 0.3 1.1 1 0 0 1 1 1 1 Glutathione peroxidase AhpC-TSA PF00578.21 CBZ27901.1 - 0.00033 20.6 0.1 0.00066 19.6 0.0 1.5 2 0 0 2 2 2 1 AhpC/TSA family Redoxin PF08534.10 CBZ27901.1 - 0.073 12.8 0.0 0.13 12.0 0.0 1.4 2 0 0 2 2 2 0 Redoxin AsnA PF03590.15 CBZ27902.1 - 7.4e-95 317.0 0.0 1e-94 316.5 0.0 1.2 1 0 0 1 1 1 1 Aspartate-ammonia ligase tRNA-synt_2 PF00152.20 CBZ27902.1 - 0.004 16.3 0.0 0.0071 15.5 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) IF3_N PF05198.16 CBZ27904.1 - 0.074 13.3 0.0 0.18 12.1 0.0 1.6 1 0 0 1 1 1 0 Translation initiation factor IF-3, N-terminal domain Exo_endo_phos PF03372.23 CBZ27905.1 - 2e-06 27.5 0.0 8e-06 25.5 0.0 2.0 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family XRN_N PF03159.18 CBZ27905.1 - 0.00023 20.7 0.0 0.00085 18.8 0.1 1.8 2 0 0 2 2 2 1 XRN 5'-3' exonuclease N-terminus FYRC PF05965.14 CBZ27906.1 - 0.00084 19.4 0.0 0.0017 18.5 0.0 1.5 1 0 0 1 1 1 1 F/Y rich C-terminus FYRN PF05964.14 CBZ27906.1 - 0.19 11.6 0.0 1.3 8.9 0.0 2.1 2 0 0 2 2 2 0 F/Y-rich N-terminus Ribosomal_S9 PF00380.19 CBZ27907.1 - 2.6e-27 95.8 1.2 3e-27 95.6 1.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S9/S16 Ribosomal_S9 PF00380.19 CBZ27908.1 - 2.6e-27 95.8 1.2 3e-27 95.6 1.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S9/S16 HSP70 PF00012.20 CBZ27909.1 - 2e-77 260.8 0.2 7.7e-41 140.0 0.0 2.7 3 0 0 3 3 3 2 Hsp70 protein MreB_Mbl PF06723.13 CBZ27909.1 - 0.001 17.9 0.1 0.62 8.8 0.0 3.2 2 1 1 3 3 3 2 MreB/Mbl protein FtsA PF14450.6 CBZ27909.1 - 0.11 12.9 0.2 3.3 8.2 0.0 3.2 3 1 0 3 3 3 0 Cell division protein FtsA OGFr_N PF04664.13 CBZ27910.1 - 2.1e-06 27.4 0.1 0.00058 19.4 0.0 2.2 2 0 0 2 2 2 2 Opioid growth factor receptor (OGFr) conserved region Med7 PF05983.11 CBZ27910.1 - 0.16 12.1 0.0 0.25 11.4 0.0 1.2 1 0 0 1 1 1 0 MED7 protein Glutaredoxin PF00462.24 CBZ27911.1 - 0.038 14.2 0.0 0.09 13.0 0.0 1.6 2 0 0 2 2 2 0 Glutaredoxin PIF1 PF05970.14 CBZ27912.1 - 3.8e-05 23.0 0.0 7e-05 22.2 0.0 1.3 1 0 0 1 1 1 1 PIF1-like helicase IstB_IS21 PF01695.17 CBZ27912.1 - 0.00018 21.3 0.1 0.0016 18.2 0.0 2.2 2 0 0 2 2 2 1 IstB-like ATP binding protein SRP54 PF00448.22 CBZ27912.1 - 0.0048 16.6 0.0 0.0094 15.6 0.0 1.4 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain Bac_DnaA PF00308.18 CBZ27912.1 - 0.015 15.2 0.1 0.05 13.4 0.0 1.8 2 0 0 2 2 2 0 Bacterial dnaA protein DUF815 PF05673.13 CBZ27912.1 - 0.028 13.6 0.0 0.051 12.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_30 PF13604.6 CBZ27912.1 - 0.13 11.9 0.1 0.33 10.7 0.1 1.6 1 1 0 1 1 1 0 AAA domain Viral_env_E26 PF11050.8 CBZ27912.1 - 0.16 11.3 0.0 0.31 10.4 0.0 1.4 1 0 0 1 1 1 0 Virus envelope protein E26 DUF3395 PF11875.8 CBZ27913.1 - 3.3e-43 147.3 0.0 5.8e-43 146.5 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3395) DnaJ PF00226.31 CBZ27913.1 - 5.2e-15 55.3 0.4 9.9e-15 54.4 0.4 1.5 1 0 0 1 1 1 1 DnaJ domain Mcp5_PH PF12814.7 CBZ27914.1 - 4.9e-25 88.0 0.6 9e-25 87.2 0.6 1.4 1 0 0 1 1 1 1 Meiotic cell cortex C-terminal pleckstrin homology NMD3 PF04981.13 CBZ27916.1 - 2.7e-77 259.5 4.0 3.8e-77 259.0 4.0 1.2 1 0 0 1 1 1 1 NMD3 family zf-RING_7 PF02591.15 CBZ27916.1 - 3.1 8.1 10.5 36 4.6 10.5 3.1 1 1 0 1 1 1 0 C4-type zinc ribbon domain TF_Zn_Ribbon PF08271.12 CBZ27916.1 - 4.1 7.0 9.7 0.6 9.7 1.2 2.9 2 1 0 2 2 2 0 TFIIB zinc-binding Pkinase PF00069.25 CBZ27917.1 - 2.3e-29 102.6 0.0 7.7e-29 100.8 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ27917.1 - 6.6e-11 42.0 0.0 6e-05 22.5 0.0 2.6 2 0 0 2 2 2 2 Protein tyrosine kinase Pox_ser-thr_kin PF05445.11 CBZ27917.1 - 0.016 14.2 0.0 0.023 13.7 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase PKD_channel PF08016.12 CBZ27918.1 - 5.3e-07 28.7 7.9 8.1e-07 28.1 7.9 1.2 1 0 0 1 1 1 1 Polycystin cation channel Ion_trans PF00520.31 CBZ27918.1 - 6.6e-06 25.5 10.6 1.4e-05 24.5 10.6 1.5 1 0 0 1 1 1 1 Ion transport protein DUF4349 PF14257.6 CBZ27918.1 - 1.9 7.9 4.4 7.9 5.9 4.4 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF4349) PRKCSH_1 PF13015.6 CBZ27919.1 - 9.5e-22 77.3 0.5 2.6e-21 75.9 0.5 1.8 1 1 0 1 1 1 1 Glucosidase II beta subunit-like protein PRKCSH PF07915.13 CBZ27919.1 - 0.00011 23.1 0.3 0.00033 21.6 0.3 1.8 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein Imm6 PF14434.6 CBZ27919.1 - 0.0062 16.5 0.2 0.013 15.5 0.2 1.4 1 0 0 1 1 1 1 Immunity protein Imm6 DUF2489 PF10675.9 CBZ27919.1 - 0.31 10.9 5.2 0.16 11.9 1.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2489) DUF4140 PF13600.6 CBZ27919.1 - 2.7 8.5 6.1 4.5 7.8 0.0 2.6 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) AAA_23 PF13476.6 CBZ27919.1 - 3 8.3 6.2 1.7 9.1 0.0 2.3 2 0 0 2 2 2 0 AAA domain TPR_MLP1_2 PF07926.12 CBZ27919.1 - 4.2 7.5 17.5 2 8.5 3.3 2.2 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein DUF3283 PF11686.8 CBZ27920.1 - 0.1 12.5 0.0 0.87 9.5 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3283) AAA_6 PF12774.7 CBZ27922.1 - 3.8e-153 509.2 0.0 3.2e-152 506.2 0.0 2.3 2 0 0 2 2 2 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 CBZ27922.1 - 5.8e-115 384.6 11.3 5.8e-115 384.6 11.3 4.0 4 1 0 4 4 4 1 Dynein heavy chain, N-terminal region 2 AAA_8 PF12780.7 CBZ27922.1 - 1.3e-98 329.5 0.3 3.9e-98 327.9 0.0 2.0 2 0 0 2 2 2 1 P-loop containing dynein motor region D4 Dynein_C PF18199.1 CBZ27922.1 - 2.1e-95 319.5 0.0 2.2e-94 316.2 0.0 2.7 3 0 0 3 3 3 1 Dynein heavy chain C-terminal domain AAA_9 PF12781.7 CBZ27922.1 - 4.7e-86 287.5 0.5 4.7e-86 287.5 0.5 2.2 2 0 0 2 2 2 1 ATP-binding dynein motor region AAA_7 PF12775.7 CBZ27922.1 - 5e-54 182.5 0.0 1.7e-49 167.8 0.0 3.7 3 0 0 3 3 3 1 P-loop containing dynein motor region MT PF12777.7 CBZ27922.1 - 5.2e-52 177.0 7.5 1.1e-51 175.9 7.5 1.5 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_lid_11 PF18198.1 CBZ27922.1 - 1.6e-51 174.4 0.0 4.8e-51 172.8 0.0 1.9 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain Dynein_heavy PF03028.15 CBZ27922.1 - 3.6e-39 133.6 0.0 1.4e-36 125.2 0.0 4.0 4 0 0 4 4 3 1 Dynein heavy chain region D6 P-loop domain AAA_5 PF07728.14 CBZ27922.1 - 2.8e-23 82.5 0.0 1.3e-05 25.2 0.0 5.9 5 2 0 5 5 5 3 AAA domain (dynein-related subfamily) Dynein_AAA_lid PF17852.1 CBZ27922.1 - 4.8e-18 65.5 0.4 8.3e-17 61.5 0.0 3.4 3 1 0 3 3 1 1 Dynein heavy chain AAA lid domain AAA_lid_1 PF17857.1 CBZ27922.1 - 5.8e-16 58.5 0.0 2.9e-15 56.3 0.0 2.3 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 CBZ27922.1 - 2.1e-07 31.5 8.7 2.3 8.6 0.0 7.4 5 1 1 6 6 6 2 AAA ATPase domain AAA PF00004.29 CBZ27922.1 - 7.9e-07 29.6 0.0 1.6 9.2 0.0 5.0 4 0 0 4 4 4 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 CBZ27922.1 - 2e-05 24.9 2.1 8.8 6.6 0.0 5.9 6 0 0 6 6 5 0 AAA domain FtsK_SpoIIIE PF01580.18 CBZ27922.1 - 4.7e-05 22.9 0.6 0.0044 16.4 0.0 3.5 3 0 0 3 3 3 1 FtsK/SpoIIIE family AAA_30 PF13604.6 CBZ27922.1 - 0.0032 17.2 0.9 2.4 7.8 0.2 4.0 3 0 0 3 3 3 1 AAA domain T2SSE PF00437.20 CBZ27922.1 - 0.0082 15.2 0.1 0.96 8.4 0.0 2.7 2 0 0 2 2 2 1 Type II/IV secretion system protein RNA_helicase PF00910.22 CBZ27922.1 - 0.026 14.9 0.0 5.4 7.5 0.0 4.0 4 0 0 4 4 3 0 RNA helicase AAA_18 PF13238.6 CBZ27922.1 - 0.045 14.3 0.0 24 5.5 0.0 4.6 5 0 0 5 5 4 0 AAA domain Viral_helicase1 PF01443.18 CBZ27922.1 - 0.12 12.0 0.0 0.57 9.9 0.0 2.2 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase OHCU_decarbox PF09349.10 CBZ27922.1 - 0.14 12.6 1.7 0.4 11.1 0.3 2.7 2 0 0 2 2 1 0 OHCU decarboxylase Aldo_ket_red PF00248.21 CBZ27923.1 - 0.0092 15.2 0.0 0.31 10.2 0.0 2.2 2 0 0 2 2 2 2 Aldo/keto reductase family Peptidase_M28 PF04389.17 CBZ27924.1 - 0.0018 18.0 0.1 0.0041 16.8 0.1 1.6 1 0 0 1 1 1 1 Peptidase family M28 Fer2 PF00111.27 CBZ27925.1 - 4.7e-12 45.7 1.0 7.5e-12 45.0 1.0 1.4 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain RRM_1 PF00076.22 CBZ27926.1 - 3e-08 33.4 0.0 5.4e-08 32.5 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Btz PF09405.10 CBZ27926.1 - 0.0017 18.6 0.0 0.0036 17.6 0.0 1.6 1 0 0 1 1 1 1 CASC3/Barentsz eIF4AIII binding Nrap_D3 PF17404.2 CBZ27928.1 - 0.11 12.5 0.6 0.41 10.7 0.1 2.0 2 0 0 2 2 2 0 Nrap protein domain 3 TROVE PF05731.11 CBZ27931.1 - 2.4e-58 198.3 0.2 7e-30 104.4 0.0 2.4 2 0 0 2 2 2 2 TROVE domain WD40 PF00400.32 CBZ27931.1 - 4.9e-15 55.7 12.5 0.014 16.3 0.0 9.1 8 0 0 8 8 8 4 WD domain, G-beta repeat DUF4062 PF13271.6 CBZ27931.1 - 3.4e-11 43.4 0.0 1.1e-10 41.7 0.0 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4062) ANAPC4_WD40 PF12894.7 CBZ27931.1 - 3.7e-05 23.9 0.0 4.5 7.6 0.0 5.3 4 1 1 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 CBZ27931.1 - 0.016 14.2 0.1 1.6 7.6 0.0 2.9 3 0 0 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein F420_ligase PF01996.16 CBZ27931.1 - 0.093 12.1 0.0 0.2 11.0 0.0 1.4 1 0 0 1 1 1 0 F420-0:Gamma-glutamyl ligase Ax_dynein_light PF10211.9 CBZ27932.1 - 3.9e-44 150.8 3.9 7e-44 150.0 3.9 1.3 1 0 0 1 1 1 1 Axonemal dynein light chain FapA PF03961.13 CBZ27932.1 - 0.2 10.2 2.9 0.3 9.6 2.9 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A APG6_N PF17675.1 CBZ27932.1 - 1.5 9.4 10.6 2.5 8.6 10.6 1.3 1 0 0 1 1 1 0 Apg6 coiled-coil region PrpR_N PF06506.11 CBZ27934.1 - 0.0095 15.5 0.2 0.039 13.5 0.1 2.0 3 0 0 3 3 3 1 Propionate catabolism activator HMD PF03201.16 CBZ27934.1 - 0.097 12.9 0.8 0.49 10.7 0.1 2.5 2 0 0 2 2 2 0 H2-forming N5,N10-methylene-tetrahydromethanopterin dehydrogenase CFEM PF05730.11 CBZ27935.1 - 1.9 8.7 7.7 0.71 10.0 1.5 2.6 2 0 0 2 2 2 0 CFEM domain PseudoU_synth_2 PF00849.22 CBZ27936.1 - 1.3e-13 51.4 1.8 7e-07 29.5 0.0 4.2 3 2 0 3 3 3 2 RNA pseudouridylate synthase TT_ORF2 PF02957.15 CBZ27936.1 - 1.1 10.2 7.5 5.1 8.0 1.9 3.5 4 0 0 4 4 4 0 TT viral ORF2 FAM199X PF15814.5 CBZ27936.1 - 3.5 6.6 5.1 0.4 9.7 0.2 1.8 2 0 0 2 2 2 0 Protein family FAM199X zf-RING_2 PF13639.6 CBZ27937.1 - 1.9e-07 31.3 4.5 1.8e-05 24.9 1.3 2.7 2 0 0 2 2 2 2 Ring finger domain zf-C3HC4_3 PF13920.6 CBZ27937.1 - 2.2e-05 24.2 4.4 0.00033 20.4 1.7 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 CBZ27937.1 - 0.001 18.9 4.3 0.0043 16.9 1.2 2.4 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_11 PF17123.5 CBZ27937.1 - 0.0018 17.9 0.4 0.48 10.2 0.0 2.8 2 0 0 2 2 2 1 RING-like zinc finger zf-RING_5 PF14634.6 CBZ27937.1 - 0.0073 16.2 4.0 0.017 15.1 1.3 2.4 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4 PF00097.25 CBZ27937.1 - 0.0075 16.1 1.1 0.0075 16.1 1.1 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 CBZ27937.1 - 0.026 14.3 6.5 0.051 13.4 2.2 2.5 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Baculo_IE-1 PF05290.11 CBZ27937.1 - 0.033 14.1 0.2 0.065 13.2 0.2 1.4 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) Spore_III_AB PF09548.10 CBZ27937.1 - 0.15 12.2 0.5 12 6.0 0.0 2.2 2 0 0 2 2 2 0 Stage III sporulation protein AB (spore_III_AB) DUF4796 PF16044.5 CBZ27937.1 - 0.15 11.6 0.8 1.3 8.6 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4796) Snapin_Pallidin PF14712.6 CBZ27937.1 - 0.27 11.7 3.7 0.55 10.7 0.4 2.1 2 0 0 2 2 2 0 Snapin/Pallidin DHR10 PF18595.1 CBZ27937.1 - 0.46 10.5 9.9 0.12 12.5 0.9 2.2 2 0 0 2 2 2 0 Designed helical repeat protein 10 domain zf-rbx1 PF12678.7 CBZ27937.1 - 0.92 9.8 4.3 0.46 10.8 0.8 2.2 2 0 0 2 2 2 0 RING-H2 zinc finger domain Ribosomal_60s PF00428.19 CBZ27938.1 - 0.013 16.1 3.6 0.013 16.1 3.6 7.1 8 2 0 8 8 8 0 60s Acidic ribosomal protein Beta_helix PF13229.6 CBZ27938.1 - 0.045 13.6 0.0 1.5 8.6 0.0 2.5 1 1 1 2 2 2 0 Right handed beta helix region SDA1 PF05285.12 CBZ27938.1 - 1 8.7 14.4 0.97 8.8 1.4 2.9 3 0 0 3 3 3 0 SDA1 FAM176 PF14851.6 CBZ27938.1 - 6.6 6.4 15.9 20 4.8 5.7 3.4 3 0 0 3 3 3 0 FAM176 family TniQ PF06527.11 CBZ27939.1 - 0.074 13.8 3.3 0.088 13.5 0.0 2.8 3 0 0 3 3 3 0 TniQ DnaJ PF00226.31 CBZ27940.1 - 4.8e-21 74.7 0.1 1.2e-20 73.3 0.1 1.8 1 0 0 1 1 1 1 DnaJ domain DnaJ-X PF14308.6 CBZ27940.1 - 0.0003 20.3 0.0 0.0017 17.8 0.0 2.1 2 0 0 2 2 2 1 X-domain of DnaJ-containing Aldo_ket_red PF00248.21 CBZ27941.1 - 4.6e-26 91.7 0.0 1.9e-22 79.8 0.0 2.1 2 0 0 2 2 2 2 Aldo/keto reductase family LRR_4 PF12799.7 CBZ27942.1 - 2.5e-11 43.6 1.2 0.00033 21.0 0.2 4.1 4 0 0 4 4 4 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CBZ27942.1 - 9.5e-11 41.3 3.3 0.00039 20.1 4.9 4.2 3 1 0 3 3 3 2 Leucine rich repeat LRR_6 PF13516.6 CBZ27942.1 - 1.4e-05 24.7 1.3 0.77 10.0 0.1 4.0 3 0 0 3 3 3 2 Leucine Rich repeat LRR_9 PF14580.6 CBZ27942.1 - 0.002 17.6 0.0 0.0089 15.5 0.0 2.0 2 0 0 2 2 2 1 Leucine-rich repeat LRR_1 PF00560.33 CBZ27942.1 - 0.029 14.9 10.2 20 6.3 0.3 5.6 6 0 0 6 6 6 0 Leucine Rich Repeat DUF2477 PF10631.9 CBZ27942.1 - 1.3 9.7 6.7 12 6.6 1.7 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2477) PTCB-BRCT PF12738.7 CBZ27943.1 - 9.5e-08 31.9 0.0 0.0044 16.9 0.0 3.8 3 0 0 3 3 3 3 twin BRCT domain BRCT PF00533.26 CBZ27943.1 - 0.00032 21.0 0.0 1.4 9.3 0.0 3.9 4 0 0 4 4 4 2 BRCA1 C Terminus (BRCT) domain CxC4 PF18717.1 CBZ27943.1 - 0.053 13.4 0.7 0.19 11.6 0.7 2.0 1 0 0 1 1 1 0 CxC4 like cysteine cluster associated with KDZ transposases HSP70 PF00012.20 CBZ27944.1 - 1.2e-243 809.7 4.3 1.4e-243 809.5 4.3 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 CBZ27944.1 - 2.7e-18 65.9 0.4 2.1e-16 59.7 0.0 2.2 2 0 0 2 2 2 2 MreB/Mbl protein FGGY_C PF02782.16 CBZ27944.1 - 0.0008 19.2 0.0 0.002 17.9 0.0 1.6 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain BcrAD_BadFG PF01869.20 CBZ27944.1 - 0.0012 18.5 0.1 0.62 9.5 0.0 2.5 2 0 0 2 2 2 2 BadF/BadG/BcrA/BcrD ATPase family Hydantoinase_A PF01968.18 CBZ27944.1 - 0.022 14.0 0.4 0.022 14.0 0.4 2.1 2 1 0 2 2 2 0 Hydantoinase/oxoprolinase DUF1464 PF07318.12 CBZ27944.1 - 0.035 13.3 0.0 0.071 12.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1464) Spore_GerAC PF05504.11 CBZ27944.1 - 0.16 12.2 0.6 1.5 9.0 0.0 2.6 3 0 0 3 3 3 0 Spore germination B3/ GerAC like, C-terminal FtsA PF14450.6 CBZ27944.1 - 0.56 10.7 6.1 3.9 7.9 0.2 3.6 3 3 0 3 3 3 0 Cell division protein FtsA DUF3602 PF12223.8 CBZ27946.1 - 0.26 11.9 1.8 3.7 8.2 0.2 3.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3602) DnaJ PF00226.31 CBZ27947.1 - 1.2e-21 76.6 0.2 2.9e-21 75.3 0.2 1.7 1 0 0 1 1 1 1 DnaJ domain DnaJ-X PF14308.6 CBZ27947.1 - 5.6e-10 39.0 0.0 3.3e-06 26.7 0.1 2.5 1 1 1 2 2 2 2 X-domain of DnaJ-containing GRAS PF03514.14 CBZ27947.1 - 0.15 11.0 0.3 0.26 10.2 0.3 1.3 1 0 0 1 1 1 0 GRAS domain family Cupin_8 PF13621.6 CBZ27949.1 - 1.3e-58 198.7 0.0 2.8e-57 194.3 0.0 2.2 1 1 0 1 1 1 1 Cupin-like domain Hepatitis_core PF00906.20 CBZ27950.1 - 0.44 10.1 1.9 0.8 9.2 1.9 1.4 1 0 0 1 1 1 0 Hepatitis core antigen PHC2_SAM_assoc PF16616.5 CBZ27951.1 - 2.7 8.8 4.9 0.42 11.4 0.8 1.7 2 0 0 2 2 2 0 Unstructured region on Polyhomeotic-like protein 1 and 2 DNA_ligase_OB_2 PF14743.6 CBZ27954.1 - 3.2e-18 65.5 0.0 6.4e-18 64.5 0.0 1.5 1 0 0 1 1 1 1 DNA ligase OB-like domain DUF4379 PF14311.6 CBZ27954.1 - 2.1e-12 47.2 1.8 2.1e-12 47.2 1.8 2.0 2 0 0 2 2 2 1 Probable Zinc-ribbon domain DNA_ligase_A_M PF01068.21 CBZ27954.1 - 3.4e-12 46.5 0.0 2.3e-05 24.2 0.0 2.8 3 0 0 3 3 3 2 ATP dependent DNA ligase domain PhnA_Zn_Ribbon PF08274.12 CBZ27954.1 - 0.19 11.7 3.9 1.1 9.3 1.3 2.4 2 0 0 2 2 2 0 PhnA Zinc-Ribbon DNA_ligase_A_M PF01068.21 CBZ27955.1 - 2e-19 70.1 0.0 5.8e-19 68.6 0.0 1.8 1 1 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_OB_2 PF14743.6 CBZ27955.1 - 4.9e-17 61.7 0.0 9.2e-17 60.8 0.0 1.5 1 0 0 1 1 1 1 DNA ligase OB-like domain DUF4379 PF14311.6 CBZ27955.1 - 4.9e-06 26.8 0.7 1e-05 25.8 0.7 1.6 1 0 0 1 1 1 1 Probable Zinc-ribbon domain Zn-ribbon_8 PF09723.10 CBZ27955.1 - 0.0041 17.2 0.5 0.013 15.6 0.5 1.9 1 0 0 1 1 1 1 Zinc ribbon domain mRNA_cap_enzyme PF01331.19 CBZ27955.1 - 0.018 14.9 0.0 6.3 6.6 0.1 3.0 2 1 0 2 2 2 0 mRNA capping enzyme, catalytic domain CCP_MauG PF03150.14 CBZ27955.1 - 0.13 12.9 0.0 0.28 11.8 0.0 1.5 1 0 0 1 1 1 0 Di-haem cytochrome c peroxidase Zn_Tnp_IS1595 PF12760.7 CBZ27955.1 - 0.13 12.2 2.5 2.2 8.4 0.1 2.6 2 0 0 2 2 2 0 Transposase zinc-ribbon domain HypA PF01155.19 CBZ27955.1 - 0.21 11.6 0.6 0.47 10.5 0.6 1.5 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Thioredoxin PF00085.20 CBZ27956.1 - 0.0056 16.6 0.0 0.18 11.8 0.0 2.8 2 0 0 2 2 2 1 Thioredoxin MMR_HSR1 PF01926.23 CBZ27957.1 - 4.9e-15 55.6 0.0 1.9e-13 50.5 0.0 2.4 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 CBZ27957.1 - 3.3e-06 26.7 0.0 8.7e-05 22.1 0.0 2.1 2 0 0 2 2 2 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 CBZ27957.1 - 0.00014 21.8 0.0 0.0019 18.1 0.0 2.2 2 0 0 2 2 2 1 RsgA GTPase GTP_EFTU PF00009.27 CBZ27957.1 - 0.0085 15.7 0.0 4.4 6.8 0.1 3.0 2 1 0 2 2 2 2 Elongation factor Tu GTP binding domain Dynamin_N PF00350.23 CBZ27957.1 - 0.011 15.8 1.1 0.34 10.9 0.2 2.7 1 1 1 2 2 2 0 Dynamin family Allexi_40kDa PF05549.11 CBZ27957.1 - 0.27 10.7 0.3 3.3 7.1 0.0 2.1 2 0 0 2 2 2 0 Allexivirus 40kDa protein Prefoldin PF02996.17 CBZ27958.1 - 2.2e-26 92.1 2.0 2.9e-26 91.7 1.4 1.5 1 1 0 1 1 1 1 Prefoldin subunit Prefoldin_2 PF01920.20 CBZ27958.1 - 0.018 15.0 3.8 0.88 9.6 0.2 2.5 2 1 0 2 2 2 0 Prefoldin subunit NBP1 PF08537.10 CBZ27958.1 - 0.02 14.3 1.7 0.067 12.6 1.7 1.7 1 1 0 1 1 1 0 Fungal Nap binding protein NBP1 End3 PF12761.7 CBZ27958.1 - 0.057 13.6 3.8 0.8 9.9 0.6 2.3 2 0 0 2 2 2 0 Actin cytoskeleton-regulatory complex protein END3 BST2 PF16716.5 CBZ27958.1 - 0.074 13.6 3.4 2.8 8.6 0.9 2.3 2 0 0 2 2 2 0 Bone marrow stromal antigen 2 YabA PF06156.13 CBZ27958.1 - 3 8.5 5.7 19 6.0 3.0 2.3 2 0 0 2 2 2 0 Initiation control protein YabA WD40 PF00400.32 CBZ27960.1 - 2.8e-16 59.6 18.8 0.00028 21.6 0.8 7.2 7 0 0 7 7 7 6 WD domain, G-beta repeat WWE PF02825.20 CBZ27960.1 - 1.8e-10 41.3 0.4 5.9e-10 39.6 0.4 1.9 1 1 0 1 1 1 1 WWE domain DnaJ PF00226.31 CBZ27961.1 - 2.1e-18 66.2 0.8 3.6e-18 65.4 0.8 1.4 1 0 0 1 1 1 1 DnaJ domain MORN PF02493.20 CBZ27962.1 - 7.9e-45 148.2 125.4 0.00012 21.8 0.5 24.2 26 0 0 26 26 26 20 MORN repeat FYVE PF01363.21 CBZ27962.1 - 5e-26 90.6 15.7 2.7e-18 65.9 6.2 2.8 2 0 0 2 2 2 2 FYVE zinc finger zf-CRD PF17979.1 CBZ27962.1 - 0.039 14.1 7.1 2.5 8.2 2.4 2.6 2 0 0 2 2 2 0 Cysteine rich domain with multizinc binding regions FYVE_2 PF02318.16 CBZ27962.1 - 1.5 9.0 11.0 7.5 6.8 1.8 2.5 2 0 0 2 2 2 0 FYVE-type zinc finger Cyt-b5 PF00173.28 CBZ27963.1 - 2e-16 59.9 0.0 3.9e-16 59.0 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain HU-CCDC81_euk_1 PF14908.6 CBZ27963.1 - 0.055 13.6 0.0 0.11 12.6 0.0 1.5 1 0 0 1 1 1 0 CCDC81 eukaryotic HU domain 1 DUF3474 PF11960.8 CBZ27963.1 - 0.17 12.1 1.6 5.4 7.2 0.1 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF3474) CYYR1 PF10873.8 CBZ27966.1 - 0.00097 19.6 0.6 0.0015 19.0 0.0 1.6 2 0 0 2 2 2 1 Cysteine and tyrosine-rich protein 1 Baculo_F PF12259.8 CBZ27966.1 - 0.015 13.8 0.5 0.02 13.4 0.5 1.1 1 0 0 1 1 1 0 Baculovirus F protein Shisa PF13908.6 CBZ27966.1 - 0.031 14.5 1.7 0.15 12.3 0.0 2.2 2 0 0 2 2 2 0 Wnt and FGF inhibitory regulator Prenyltrans PF00432.21 CBZ27967.1 - 1.2e-21 76.2 13.1 0.00011 21.8 0.0 5.8 5 0 0 5 5 5 5 Prenyltransferase and squalene oxidase repeat SQHop_cyclase_N PF13249.6 CBZ27967.1 - 0.14 11.2 0.0 0.34 10.0 0.0 1.6 1 0 0 1 1 1 0 Squalene-hopene cyclase N-terminal domain COG7 PF10191.9 CBZ27968.1 - 9.3e-10 37.4 9.9 0.0018 16.6 0.4 5.5 6 0 0 6 6 6 4 Golgi complex component 7 (COG7) MoCF_biosynth PF00994.24 CBZ27968.1 - 0.0046 16.6 0.1 0.13 11.9 0.0 2.6 2 0 0 2 2 2 1 Probable molybdopterin binding domain DUF4378 PF14309.6 CBZ27968.1 - 0.0079 16.6 0.3 0.25 11.7 0.0 3.2 3 1 0 3 3 3 1 Domain of unknown function (DUF4378) AIP3 PF03915.13 CBZ27968.1 - 0.036 13.2 3.9 0.96 8.5 0.2 2.3 2 0 0 2 2 2 0 Actin interacting protein 3 STN1_2 PF09170.10 CBZ27968.1 - 0.062 13.5 0.1 0.37 11.0 0.1 2.3 1 0 0 1 1 1 0 CST, Suppressor of cdc thirteen homolog, complex subunit STN1 MitMem_reg PF13012.6 CBZ27968.1 - 0.39 11.1 2.9 8 6.9 0.1 3.6 3 1 0 3 3 3 0 Maintenance of mitochondrial structure and function DUF2497 PF10691.9 CBZ27968.1 - 0.47 10.9 5.5 33 5.0 0.0 5.0 5 0 0 5 5 5 0 Protein of unknown function (DUF2497) DUF948 PF06103.11 CBZ27968.1 - 1.6 9.1 4.7 5.8 7.2 0.2 3.5 3 1 0 3 3 3 0 Bacterial protein of unknown function (DUF948) TerB PF05099.13 CBZ27968.1 - 8.3 6.4 8.4 1.3 9.0 2.2 2.6 2 0 0 2 2 2 0 Tellurite resistance protein TerB PhoD PF09423.10 CBZ27969.1 - 0.00013 21.1 0.0 0.0018 17.3 0.0 2.3 2 1 0 2 2 2 1 PhoD-like phosphatase Abhydrolase_6 PF12697.7 CBZ27972.1 - 1.6e-13 51.8 0.1 2.8e-13 51.0 0.1 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 CBZ27972.1 - 0.00013 21.3 2.7 0.13 11.5 0.1 3.8 3 1 0 3 3 3 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 CBZ27972.1 - 0.0017 18.0 0.1 0.025 14.2 0.0 2.2 2 0 0 2 2 2 1 alpha/beta hydrolase fold DUF915 PF06028.11 CBZ27972.1 - 0.002 17.5 0.0 0.0054 16.1 0.0 1.6 2 0 0 2 2 2 1 Alpha/beta hydrolase of unknown function (DUF915) RRM_1 PF00076.22 CBZ27973.1 - 4.2e-16 58.5 0.0 6.5e-16 57.9 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 CBZ27973.1 - 1.6e-05 24.5 0.0 2.9e-05 23.7 0.0 1.5 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CBZ27973.1 - 0.0032 17.6 0.0 0.0067 16.5 0.0 1.7 1 1 0 1 1 1 1 RNA recognition motif PHM7_cyt PF14703.6 CBZ27973.1 - 0.074 13.3 0.1 1.6 9.0 0.1 2.2 1 1 1 2 2 2 0 Cytosolic domain of 10TM putative phosphate transporter Glutaredoxin PF00462.24 CBZ27974.1 - 4.5e-06 26.8 0.0 1.3e-05 25.3 0.0 1.8 1 0 0 1 1 1 1 Glutaredoxin GST_N_3 PF13417.6 CBZ27974.1 - 2.8e-05 24.4 0.0 7e-05 23.2 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain DUF3918 PF13056.6 CBZ27974.1 - 0.041 13.5 0.0 0.087 12.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3918) GST_N PF02798.20 CBZ27974.1 - 0.047 14.0 0.0 0.12 12.8 0.0 1.7 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 CBZ27974.1 - 0.16 12.3 0.0 0.69 10.3 0.0 2.1 1 1 0 1 1 1 0 Glutathione S-transferase, N-terminal domain 3HCDH_N PF02737.18 CBZ27975.1 - 2.9e-52 177.1 3.5 5.8e-52 176.2 3.5 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.22 CBZ27975.1 - 1.2e-35 121.9 0.4 7.7e-23 80.9 0.0 3.4 4 0 0 4 4 3 2 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain ECH_1 PF00378.20 CBZ27975.1 - 1.5e-28 99.8 0.5 1.5e-28 99.8 0.5 2.0 2 1 0 2 2 2 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 CBZ27975.1 - 1.5e-19 70.7 1.2 3.2e-19 69.6 0.2 2.0 2 0 0 2 2 2 1 Enoyl-CoA hydratase/isomerase NAD_binding_2 PF03446.15 CBZ27975.1 - 2e-05 24.8 0.4 5.8e-05 23.3 0.4 1.9 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 CBZ27975.1 - 0.0061 17.1 2.3 0.033 14.8 2.3 2.2 1 1 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Penicillinase_R PF03965.16 CBZ27975.1 - 0.018 15.4 0.2 2 8.8 0.0 2.7 2 0 0 2 2 2 0 Penicillinase repressor NAD_Gly3P_dh_N PF01210.23 CBZ27975.1 - 0.045 13.7 0.2 0.1 12.6 0.2 1.7 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Sacchrp_dh_NADP PF03435.18 CBZ27975.1 - 0.045 14.0 2.3 0.057 13.7 0.6 2.1 3 0 0 3 3 3 0 Saccharopine dehydrogenase NADP binding domain 2-Hacid_dh_C PF02826.19 CBZ27975.1 - 0.088 12.2 0.2 0.21 10.9 0.1 1.6 1 1 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DAO PF01266.24 CBZ27975.1 - 0.11 12.1 0.1 0.2 11.2 0.1 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase Shikimate_DH PF01488.20 CBZ27975.1 - 0.71 9.9 4.3 3.6 7.7 2.0 2.9 2 1 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase SNF2_N PF00176.23 CBZ27976.1 - 8.1e-27 93.8 1.3 1.8e-18 66.4 0.0 3.0 2 1 0 2 2 2 2 SNF2 family N-terminal domain zf-RING_UBOX PF13445.6 CBZ27976.1 - 2.5e-07 30.6 1.2 1e-06 28.6 1.2 2.2 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 CBZ27976.1 - 2.4e-06 27.3 4.6 8.7e-06 25.5 4.6 2.1 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Helicase_C PF00271.31 CBZ27976.1 - 4.6e-06 26.9 0.0 9e-06 26.0 0.0 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-RING_2 PF13639.6 CBZ27976.1 - 5.3e-06 26.7 4.3 5.3e-06 26.7 4.3 2.9 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_3 PF13920.6 CBZ27976.1 - 5.5e-06 26.1 5.4 5.5e-06 26.1 5.4 3.2 5 0 0 5 5 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CBZ27976.1 - 4.8e-05 23.2 4.4 4.8e-05 23.2 4.4 2.2 2 0 0 2 2 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 CBZ27976.1 - 0.00019 21.2 7.7 0.00019 21.2 7.7 2.6 2 1 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 CBZ27976.1 - 0.00084 19.4 5.4 0.00084 19.4 5.4 2.6 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING DEAD PF00270.29 CBZ27976.1 - 0.0038 17.0 0.0 0.0077 16.0 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Prok-RING_4 PF14447.6 CBZ27976.1 - 0.0051 16.7 4.2 0.0051 16.7 4.2 2.5 3 0 0 3 3 2 1 Prokaryotic RING finger family 4 zf-RING_10 PF16685.5 CBZ27976.1 - 7.2 6.8 7.2 3.4 7.9 3.7 2.3 2 0 0 2 2 2 0 zinc RING finger of MSL2 Peptidase_M3 PF01432.20 CBZ27977.1 - 2.2e-117 393.2 0.0 1.5e-116 390.4 0.0 1.9 2 0 0 2 2 2 1 Peptidase family M3 Peptidase_M50B PF13398.6 CBZ27977.1 - 0.058 13.0 0.3 0.099 12.3 0.3 1.3 1 0 0 1 1 1 0 Peptidase M50B-like PQQ_2 PF13360.6 CBZ27978.1 - 0.013 15.1 0.1 0.033 13.8 0.1 1.6 1 0 0 1 1 1 0 PQQ-like domain EF-hand_1 PF00036.32 CBZ27979.1 - 0.066 12.8 0.0 0.15 11.7 0.0 1.6 1 0 0 1 1 1 0 EF hand U-box PF04564.15 CBZ27980.1 - 0.00051 20.2 0.0 0.0018 18.4 0.0 1.9 2 0 0 2 2 2 1 U-box domain DciA PF05258.12 CBZ27980.1 - 0.067 13.6 0.1 0.22 11.9 0.0 1.8 2 0 0 2 2 2 0 Dna[CI] antecedent, DciA Pro_dh PF01619.18 CBZ27981.1 - 5.3e-63 213.3 0.3 8.4e-63 212.6 0.3 1.2 1 0 0 1 1 1 1 Proline dehydrogenase AP_endonuc_2 PF01261.24 CBZ27981.1 - 2.6e-05 23.7 0.0 0.0038 16.7 0.0 2.3 2 0 0 2 2 2 2 Xylose isomerase-like TIM barrel EF-hand_7 PF13499.6 CBZ27981.1 - 0.022 15.2 0.0 0.045 14.2 0.0 1.5 1 0 0 1 1 1 0 EF-hand domain pair DUF1133 PF06576.11 CBZ27981.1 - 0.14 11.5 0.0 0.57 9.6 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1133) CbtA PF09490.10 CBZ27981.1 - 0.17 11.6 0.0 0.3 10.8 0.0 1.3 1 0 0 1 1 1 0 Probable cobalt transporter subunit (CbtA) CTP_transf_1 PF01148.20 CBZ27982.1 - 1.4e-63 215.1 16.9 2e-63 214.6 16.9 1.2 1 0 0 1 1 1 1 Cytidylyltransferase family Ribosomal_S28e PF01200.18 CBZ27983.1 - 1.9e-29 101.4 0.8 2.4e-29 101.1 0.8 1.1 1 0 0 1 1 1 1 Ribosomal protein S28e Ribosomal_S28e PF01200.18 CBZ27984.1 - 1.9e-29 101.4 0.8 2.4e-29 101.1 0.8 1.1 1 0 0 1 1 1 1 Ribosomal protein S28e MIT PF04212.18 CBZ27985.1 - 1.6e-05 24.9 0.1 3e-05 24.0 0.1 1.5 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain Spo0A_C PF08769.11 CBZ27985.1 - 0.053 13.6 0.0 0.12 12.4 0.0 1.6 1 0 0 1 1 1 0 Sporulation initiation factor Spo0A C terminal LRR_6 PF13516.6 CBZ27986.1 - 8e-05 22.4 7.2 3.7 7.9 0.0 6.0 6 0 0 6 6 6 2 Leucine Rich repeat LRR_8 PF13855.6 CBZ27986.1 - 0.01 15.6 1.4 5.7 6.8 0.0 4.7 6 0 0 6 6 6 1 Leucine rich repeat Flavi_NS2A PF01005.19 CBZ27986.1 - 0.031 14.4 0.0 0.097 12.8 0.0 1.7 1 1 0 1 1 1 0 Flavivirus non-structural protein NS2A LRR_1 PF00560.33 CBZ27986.1 - 0.044 14.3 9.2 10 7.1 0.0 5.8 6 0 0 6 6 6 0 Leucine Rich Repeat LRR_4 PF12799.7 CBZ27986.1 - 0.72 10.4 8.5 35 5.0 1.2 5.1 3 2 1 4 4 4 0 Leucine Rich repeats (2 copies) FA_desaturase PF00487.24 CBZ27988.1 - 1.4e-22 80.7 25.3 1.9e-22 80.3 25.3 1.1 1 0 0 1 1 1 1 Fatty acid desaturase Lipid_DES PF08557.10 CBZ27988.1 - 0.002 17.6 0.2 0.0035 16.8 0.2 1.4 1 0 0 1 1 1 1 Sphingolipid Delta4-desaturase (DES) Lipid_DES PF08557.10 CBZ27989.1 - 0.00018 20.9 0.2 0.00025 20.5 0.2 1.3 1 0 0 1 1 1 1 Sphingolipid Delta4-desaturase (DES) FA_desaturase PF00487.24 CBZ27990.1 - 1.7e-22 80.5 25.3 2.2e-22 80.1 25.3 1.1 1 0 0 1 1 1 1 Fatty acid desaturase Lipid_DES PF08557.10 CBZ27990.1 - 0.0021 17.5 0.2 0.0037 16.7 0.2 1.4 1 0 0 1 1 1 1 Sphingolipid Delta4-desaturase (DES) Pkinase PF00069.25 CBZ27993.1 - 4.9e-58 196.6 0.0 7.8e-58 195.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ27993.1 - 1.8e-35 122.4 0.0 2.8e-35 121.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CBZ27993.1 - 1.5e-06 27.7 0.0 0.0007 19.0 0.0 2.4 2 0 0 2 2 2 2 Kinase-like PAS PF00989.25 CBZ27993.1 - 2.7e-06 27.3 0.0 8.2e-06 25.8 0.0 1.8 1 0 0 1 1 1 1 PAS fold Pkinase_fungal PF17667.1 CBZ27993.1 - 1.2e-05 24.2 0.0 2.3e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 CBZ27993.1 - 0.0001 21.7 0.0 0.00052 19.4 0.0 2.0 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family PAS_4 PF08448.10 CBZ27993.1 - 0.00042 20.5 0.0 0.002 18.4 0.0 2.0 2 0 0 2 2 2 1 PAS fold PAS_9 PF13426.7 CBZ27993.1 - 0.0026 18.0 0.0 0.011 16.0 0.0 2.0 2 0 0 2 2 2 1 PAS domain PAS_8 PF13188.7 CBZ27993.1 - 0.0038 17.2 0.0 0.015 15.4 0.0 2.0 1 0 0 1 1 1 1 PAS domain PAS_10 PF13596.6 CBZ27993.1 - 0.032 14.8 0.0 0.1 13.2 0.0 1.8 1 0 0 1 1 1 0 PAS domain Zap1_zf2 PF18217.1 CBZ27993.1 - 0.033 14.2 0.2 0.12 12.4 0.2 1.9 1 0 0 1 1 1 0 Zap1 zinc finger 2 FTA2 PF13095.6 CBZ27993.1 - 0.034 13.8 0.0 0.24 11.0 0.0 2.1 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 HrpB1_HrpK PF09613.10 CBZ27995.1 - 0.021 14.5 0.1 0.092 12.4 0.1 2.1 1 0 0 1 1 1 0 Bacterial type III secretion protein (HrpB1_HrpK) RIIa PF02197.17 CBZ27997.1 - 0.063 13.0 0.0 0.1 12.3 0.0 1.3 1 0 0 1 1 1 0 Regulatory subunit of type II PKA R-subunit Radial_spoke PF04712.12 CBZ27997.1 - 0.075 12.0 0.0 0.077 11.9 0.0 1.1 1 0 0 1 1 1 0 Radial spokehead-like protein NuA4 PF09340.10 CBZ28000.1 - 3.1e-08 33.4 0.0 5.1e-06 26.3 0.0 2.4 2 0 0 2 2 2 2 Histone acetyltransferase subunit NuA4 HEAT PF02985.22 CBZ28001.1 - 0.00084 19.4 0.4 1 9.8 0.0 4.5 3 0 0 3 3 3 1 HEAT repeat Cnd1 PF12717.7 CBZ28001.1 - 0.0091 16.1 0.0 0.03 14.4 0.0 2.0 1 0 0 1 1 1 1 non-SMC mitotic condensation complex subunit 1 EURL PF06937.11 CBZ28001.1 - 0.028 13.9 0.6 1.4 8.3 0.0 2.3 2 0 0 2 2 2 0 EURL protein Adaptin_N PF01602.20 CBZ28001.1 - 0.058 11.9 0.0 0.13 10.8 0.0 1.5 1 0 0 1 1 1 0 Adaptin N terminal region PSRT PF07636.11 CBZ28001.1 - 0.75 9.5 3.9 2.2 8.0 3.9 1.8 1 0 0 1 1 1 0 PSRT DNA_binding_1 PF01035.20 CBZ28002.1 - 4.7e-21 74.7 0.6 2.2e-20 72.6 0.0 2.1 2 0 0 2 2 2 1 6-O-methylguanine DNA methyltransferase, DNA binding domain zf-C2H2_4 PF13894.6 CBZ28003.1 - 0.0012 19.5 1.9 0.74 10.8 0.1 3.2 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.26 CBZ28003.1 - 0.0046 17.3 5.1 0.52 10.9 0.4 3.4 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-Di19 PF05605.12 CBZ28003.1 - 0.059 13.7 0.0 0.18 12.1 0.0 1.8 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding Zn_Tnp_IS1595 PF12760.7 CBZ28003.1 - 0.71 9.9 3.8 9 6.4 0.1 2.4 2 0 0 2 2 2 0 Transposase zinc-ribbon domain ELMO_CED12 PF04727.13 CBZ28007.1 - 1.4e-42 145.8 0.0 1.9e-42 145.3 0.0 1.2 1 0 0 1 1 1 1 ELMO/CED-12 family LRR_4 PF12799.7 CBZ28009.1 - 0.0072 16.7 1.4 4.9 7.7 0.0 3.9 4 0 0 4 4 4 1 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CBZ28009.1 - 0.014 15.2 0.6 25 4.7 0.1 4.2 5 0 0 5 5 5 0 Leucine rich repeat LRR_6 PF13516.6 CBZ28009.1 - 0.014 15.4 12.4 0.69 10.1 0.2 5.5 6 0 0 6 6 6 0 Leucine Rich repeat DUF4460 PF14687.6 CBZ28010.1 - 3.3e-08 33.6 0.0 8e-08 32.3 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4460) DUF4461 PF14688.6 CBZ28010.1 - 0.049 13.4 3.5 0.34 10.7 2.6 2.5 1 1 0 2 2 2 0 Domain of unknown function (DUF4461) DUF2959 PF11172.8 CBZ28010.1 - 0.18 11.9 2.1 3 8.0 0.4 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2959) Sedlin_N PF04628.13 CBZ28011.1 - 0.0054 16.9 0.0 0.0092 16.1 0.0 1.3 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region HEAT_2 PF13646.6 CBZ28013.1 - 1e-26 93.1 9.4 2.6e-15 56.6 0.8 3.2 2 1 1 3 3 3 3 HEAT repeats HEAT_PBS PF03130.16 CBZ28013.1 - 5.1e-18 63.9 11.9 0.001 19.5 0.1 6.1 6 0 0 6 6 6 4 PBS lyase HEAT-like repeat HEAT PF02985.22 CBZ28013.1 - 4e-07 29.7 6.5 0.0042 17.2 0.0 5.5 6 0 0 6 6 6 2 HEAT repeat HEAT_EZ PF13513.6 CBZ28013.1 - 0.00035 21.0 3.8 0.082 13.4 0.8 4.1 3 1 0 3 3 3 1 HEAT-like repeat DUF5463 PF17551.2 CBZ28013.1 - 0.048 13.6 0.1 0.1 12.5 0.1 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5463) DMRT-like PF15791.5 CBZ28013.1 - 0.29 11.6 4.9 1.7 9.0 0.9 2.9 2 1 0 2 2 2 0 Doublesex-and mab-3-related transcription factor C1 and C2 TRAM_LAG1_CLN8 PF03798.16 CBZ28014.1 - 3.6e-18 66.0 17.0 3.6e-18 66.0 17.0 1.4 2 0 0 2 2 2 1 TLC domain DUF4457 PF14652.6 CBZ28015.1 - 7.9e-21 74.6 0.0 2.4e-07 30.3 0.0 4.9 5 0 0 5 5 5 3 Domain of unknown function (DUF4457) 4HBT_2 PF13279.6 CBZ28016.1 - 4.5e-10 40.1 0.0 6.5e-10 39.6 0.0 1.3 1 0 0 1 1 1 1 Thioesterase-like superfamily 4HBT PF03061.22 CBZ28016.1 - 1.5e-08 34.9 0.0 3.9e-07 30.3 0.0 2.3 2 0 0 2 2 2 1 Thioesterase superfamily Acyl-ACP_TE PF01643.17 CBZ28016.1 - 0.013 14.7 0.0 0.075 12.3 0.0 1.9 1 1 0 1 1 1 0 Acyl-ACP thioesterase PUB_1 PF18486.1 CBZ28017.1 - 0.00065 19.5 4.9 2.7 7.9 0.1 5.4 5 0 0 5 5 5 2 PNGase/UBA- or UBX-containing domain MT PF12777.7 CBZ28017.1 - 0.0073 15.4 0.0 0.014 14.5 0.0 1.4 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor T4_tail_cap PF11091.8 CBZ28017.1 - 0.014 14.4 0.0 31 3.3 0.0 3.2 3 0 0 3 3 3 0 Tail-tube assembly protein UPF0058 PF01893.16 CBZ28017.1 - 0.092 13.0 2.5 1.1e+02 3.2 0.0 4.1 4 0 0 4 4 4 0 Uncharacterised protein family UPF0058 DUF3552 PF12072.8 CBZ28017.1 - 0.72 9.2 10.9 1.1 8.6 2.8 3.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3552) HAUS6_N PF14661.6 CBZ28017.1 - 0.72 9.4 2.7 15 5.1 0.5 2.5 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 6 N-terminus BRE1 PF08647.11 CBZ28017.1 - 9.7 6.3 9.4 24 5.1 0.9 2.6 2 0 0 2 2 2 0 BRE1 E3 ubiquitin ligase Jnk-SapK_ap_N PF09744.9 CBZ28018.1 - 0.016 15.5 5.9 0.016 15.5 5.9 2.4 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 SCO1-SenC PF02630.14 CBZ28019.1 - 1.1e-45 154.9 0.0 1.6e-45 154.3 0.0 1.3 1 0 0 1 1 1 1 SCO1/SenC Thioredoxin_8 PF13905.6 CBZ28019.1 - 0.0024 18.1 0.0 0.0045 17.3 0.0 1.6 1 1 0 1 1 1 1 Thioredoxin-like AhpC-TSA PF00578.21 CBZ28019.1 - 0.004 17.1 0.0 0.0083 16.0 0.0 1.7 1 1 0 1 1 1 1 AhpC/TSA family Methyltransf_31 PF13847.6 CBZ28022.1 - 1.6e-12 47.5 0.0 2.2e-05 24.3 0.0 2.4 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_23 PF13489.6 CBZ28022.1 - 1.7e-12 47.5 0.0 2.9e-12 46.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CBZ28022.1 - 4.7e-11 43.2 0.0 8.3e-08 32.8 0.0 2.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CBZ28022.1 - 9.1e-10 39.1 0.0 2.3e-05 25.0 0.0 3.1 1 1 2 3 3 3 2 Methyltransferase domain Methyltransf_12 PF08242.12 CBZ28022.1 - 1.6e-09 38.4 0.0 3.1e-08 34.2 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain DREV PF05219.12 CBZ28022.1 - 0.0017 17.5 0.0 0.0036 16.5 0.0 1.5 1 1 0 1 1 1 1 DREV methyltransferase CMAS PF02353.20 CBZ28022.1 - 0.016 14.6 0.0 0.03 13.6 0.0 1.5 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase PHD PF00628.29 CBZ28023.1 - 0.0014 18.5 4.5 0.0026 17.6 4.5 1.5 1 0 0 1 1 1 1 PHD-finger Zn_ribbon_17 PF17120.5 CBZ28023.1 - 0.19 11.4 2.9 0.42 10.3 2.9 1.5 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type SBE2 PF17076.5 CBZ28023.1 - 0.63 8.2 21.6 0.056 11.7 16.7 1.6 1 1 1 2 2 2 0 SBE2, cell-wall formation DUF1179 PF06678.11 CBZ28023.1 - 8 6.5 6.7 4 7.5 3.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1179) ATG22 PF11700.8 CBZ28025.1 - 0.0071 15.0 0.0 0.012 14.3 0.0 1.3 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like HEAT PF02985.22 CBZ28025.1 - 0.38 11.1 4.1 0.91 10.0 0.1 3.5 3 0 0 3 3 3 0 HEAT repeat PQ-loop PF04193.14 CBZ28026.1 - 4.5e-19 68.0 1.6 4.8e-15 55.1 0.0 2.8 3 0 0 3 3 3 2 PQ loop repeat ER_lumen_recept PF00810.18 CBZ28026.1 - 0.0041 18.0 0.3 0.0041 18.0 0.3 2.1 2 0 0 2 2 2 1 ER lumen protein retaining receptor GPI2 PF06432.11 CBZ28026.1 - 4.8 6.5 6.7 0.32 10.4 1.6 1.6 2 0 0 2 2 2 0 Phosphatidylinositol N-acetylglucosaminyltransferase Pkinase PF00069.25 CBZ28028.1 - 2.2e-13 50.2 0.0 6.6e-09 35.5 0.0 3.0 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ28028.1 - 3.9e-08 32.9 0.2 0.00021 20.7 0.0 3.1 3 0 0 3 3 3 2 Protein tyrosine kinase Peptidase_C48 PF02902.19 CBZ28029.1 - 4.7e-14 52.7 0.0 4.1e-06 26.8 0.0 2.4 2 0 0 2 2 2 2 Ulp1 protease family, C-terminal catalytic domain Metallophos PF00149.28 CBZ28032.1 - 3.3e-15 57.1 0.0 6.2e-13 49.7 0.0 2.9 3 0 0 3 3 3 2 Calcineurin-like phosphoesterase Pkinase PF00069.25 CBZ28033.1 - 2e-32 112.6 0.0 3.7e-15 56.0 0.0 3.7 4 0 0 4 4 4 2 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ28033.1 - 2.1e-06 27.2 0.0 4.4e-05 22.9 0.0 2.8 4 0 0 4 4 4 1 Protein tyrosine kinase Haspin_kinase PF12330.8 CBZ28033.1 - 0.00018 20.6 0.0 0.0003 19.8 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Pkinase_fungal PF17667.1 CBZ28033.1 - 0.048 12.4 0.0 0.088 11.6 0.0 1.4 1 0 0 1 1 1 0 Fungal protein kinase Pkinase PF00069.25 CBZ28034.1 - 1.2e-06 28.1 0.0 0.0004 19.8 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Nudix_N_2 PF14803.6 CBZ28034.1 - 0.093 12.7 1.7 11 6.0 0.0 3.8 3 0 0 3 3 3 0 Nudix N-terminal DUF1461 PF07314.11 CBZ28035.1 - 0.16 11.9 0.0 0.2 11.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1461) Pet191_N PF10203.9 CBZ28036.1 - 0.0085 16.4 3.3 0.12 12.7 0.4 2.2 1 1 1 2 2 2 2 Cytochrome c oxidase assembly protein PET191 FtsJ PF01728.19 CBZ28037.1 - 3.7e-05 23.9 0.0 0.00012 22.3 0.0 1.7 1 1 0 1 1 1 1 FtsJ-like methyltransferase HrpB2 PF09487.10 CBZ28038.1 - 0.067 13.6 4.5 0.34 11.4 4.5 2.3 1 0 0 1 1 1 0 Bacterial type III secretion protein (HrpB2) Cornifin PF02389.15 CBZ28039.1 - 4.8e-88 292.3 254.6 0.00051 20.3 1.2 29.9 3 2 30 34 34 34 33 Cornifin (SPRR) family Arf PF00025.21 CBZ28041.1 - 5.1e-23 81.4 0.2 3.1e-09 36.5 0.0 4.3 4 0 0 4 4 4 3 ADP-ribosylation factor family G-alpha PF00503.20 CBZ28041.1 - 2.1e-06 27.2 0.0 0.00055 19.2 0.0 2.4 2 1 0 2 2 2 2 G-protein alpha subunit AAA_28 PF13521.6 CBZ28041.1 - 0.0014 18.9 0.0 0.0043 17.3 0.0 1.9 1 0 0 1 1 1 1 AAA domain SRPRB PF09439.10 CBZ28041.1 - 0.0019 17.6 0.0 3.1 7.2 0.0 2.9 3 0 0 3 3 3 2 Signal recognition particle receptor beta subunit Roc PF08477.13 CBZ28041.1 - 0.0035 17.6 0.0 2.9 8.1 0.0 2.5 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase ABC_tran PF00005.27 CBZ28041.1 - 0.0096 16.4 0.0 0.048 14.2 0.0 2.0 2 0 0 2 2 2 1 ABC transporter AAA_29 PF13555.6 CBZ28041.1 - 0.0099 15.6 0.0 0.02 14.6 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain GTP_EFTU PF00009.27 CBZ28041.1 - 0.025 14.1 0.0 5.4 6.5 0.0 2.2 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 CBZ28041.1 - 0.043 13.9 0.3 0.25 11.5 0.1 2.4 1 1 1 2 2 2 0 50S ribosome-binding GTPase AAA_22 PF13401.6 CBZ28041.1 - 0.17 12.2 0.1 1.7 8.9 0.0 2.3 2 0 0 2 2 2 0 AAA domain RsgA_GTPase PF03193.16 CBZ28041.1 - 0.19 11.6 0.0 22 4.9 0.0 2.3 2 0 0 2 2 2 0 RsgA GTPase 3-alpha PF03475.14 CBZ28041.1 - 2 8.3 4.2 24 4.9 0.2 2.6 2 0 0 2 2 2 0 3-alpha domain AAA_22 PF13401.6 CBZ28043.1 - 6.7e-06 26.4 0.1 0.069 13.4 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.6 CBZ28043.1 - 1e-05 26.0 7.8 3.2e-05 24.4 0.1 3.4 3 1 0 3 3 3 2 AAA ATPase domain Kinesin PF00225.23 CBZ28043.1 - 0.0089 15.0 0.0 0.02 13.8 0.0 1.5 1 0 0 1 1 1 1 Kinesin motor domain CoaE PF01121.20 CBZ28043.1 - 0.066 12.9 0.0 0.25 11.0 0.0 2.0 1 0 0 1 1 1 0 Dephospho-CoA kinase Ribosomal_L38e PF01781.18 CBZ28044.1 - 2.9e-29 101.0 4.0 3.4e-29 100.7 4.0 1.1 1 0 0 1 1 1 1 Ribosomal L38e protein family GDP_Man_Dehyd PF16363.5 CBZ28045.1 - 1.5e-62 212.0 0.0 7.4e-57 193.2 0.0 2.0 2 0 0 2 2 2 2 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 CBZ28045.1 - 2.9e-49 167.7 0.1 5e-49 166.9 0.1 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 CBZ28045.1 - 6.1e-21 74.8 0.0 5.7e-18 65.0 0.0 2.1 2 0 0 2 2 2 2 Male sterility protein 3Beta_HSD PF01073.19 CBZ28045.1 - 3.7e-18 65.5 0.0 6.6e-13 48.3 0.0 2.1 2 0 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 CBZ28045.1 - 1.3e-17 63.9 0.6 8.9e-17 61.1 0.7 1.9 2 0 0 2 2 2 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 CBZ28045.1 - 3.5e-16 59.2 0.0 1.8e-10 40.4 0.0 3.0 2 1 0 2 2 2 2 Polysaccharide biosynthesis protein ThiF PF00899.21 CBZ28045.1 - 0.082 12.2 0.1 1.2 8.4 0.0 2.1 2 0 0 2 2 2 0 ThiF family Aminotran_5 PF00266.19 CBZ28046.1 - 1.2e-14 54.1 0.0 1.8e-14 53.5 0.0 1.3 1 1 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.20 CBZ28046.1 - 3.4e-05 22.6 0.0 5e-05 22.0 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.17 CBZ28046.1 - 0.16 11.2 0.2 0.49 9.6 0.1 1.7 2 0 0 2 2 2 0 DegT/DnrJ/EryC1/StrS aminotransferase family DUF2383 PF09537.10 CBZ28047.1 - 0.16 12.3 0.1 0.68 10.3 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF2383) Sec1 PF00995.23 CBZ28048.1 - 6.7e-87 293.1 0.0 7.8e-87 292.8 0.0 1.0 1 0 0 1 1 1 1 Sec1 family MRP-S34 PF16053.5 CBZ28049.1 - 6.7e-06 25.8 0.0 9.9e-06 25.2 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial 28S ribosomal protein S34 CN_hydrolase PF00795.22 CBZ28050.1 - 2.3e-49 168.1 0.0 2.6e-49 167.9 0.0 1.0 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Esterase PF00756.20 CBZ28051.1 - 0.055 13.1 0.0 0.12 12.0 0.0 1.6 1 0 0 1 1 1 0 Putative esterase YvrJ PF12841.7 CBZ28052.1 - 0.1 12.2 0.9 2 8.0 0.1 3.4 2 0 0 2 2 2 0 YvrJ protein family Tnp_22_trimer PF17489.2 CBZ28052.1 - 0.31 11.0 2.5 11 6.1 0.1 4.4 5 0 0 5 5 5 0 L1 transposable element trimerization domain Cauli_DNA-bind PF03310.13 CBZ28052.1 - 5 7.2 6.7 4.6 7.3 0.5 3.7 3 0 0 3 3 3 0 Caulimovirus DNA-binding protein AMH_N PF04709.12 CBZ28053.1 - 0.018 14.0 0.6 0.02 13.8 0.6 1.1 1 0 0 1 1 1 0 Anti-Mullerian hormone, N terminal region WD40 PF00400.32 CBZ28055.1 - 2.2e-08 34.6 9.3 0.021 15.7 1.0 5.0 5 0 0 5 5 5 3 WD domain, G-beta repeat BUD22 PF09073.10 CBZ28055.1 - 0.00021 20.7 23.0 0.00021 20.7 23.0 2.1 2 0 0 2 2 2 1 BUD22 QRPTase_C PF01729.19 CBZ28055.1 - 0.0077 16.0 0.6 0.018 14.8 0.6 1.5 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, C-terminal domain NOA36 PF06524.12 CBZ28055.1 - 0.09 12.1 19.0 0.17 11.2 19.0 1.4 1 0 0 1 1 1 0 NOA36 protein PQQ_3 PF13570.6 CBZ28055.1 - 0.28 11.7 8.1 24 5.6 0.2 4.6 4 0 0 4 4 4 0 PQQ-like domain DUF4533 PF15047.6 CBZ28055.1 - 0.37 10.3 7.6 0.029 13.9 2.6 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF4533) CDC45 PF02724.14 CBZ28055.1 - 0.76 8.0 22.2 1.3 7.3 20.3 2.0 2 0 0 2 2 2 0 CDC45-like protein Ribosomal_L29 PF00831.23 CBZ28056.1 - 1.5e-18 66.5 2.2 1.5e-18 66.5 2.2 2.2 2 1 0 2 2 2 1 Ribosomal L29 protein MRP-L47 PF06984.13 CBZ28056.1 - 0.026 14.6 0.5 0.026 14.6 0.5 2.0 2 0 0 2 2 2 0 Mitochondrial 39-S ribosomal protein L47 (MRP-L47) Ribosomal_L29 PF00831.23 CBZ28057.1 - 1.5e-18 66.5 2.2 1.5e-18 66.5 2.2 2.2 2 1 0 2 2 2 1 Ribosomal L29 protein MRP-L47 PF06984.13 CBZ28057.1 - 0.026 14.6 0.5 0.026 14.6 0.5 2.0 2 0 0 2 2 2 0 Mitochondrial 39-S ribosomal protein L47 (MRP-L47) Sec1 PF00995.23 CBZ28059.1 - 1.3e-87 295.4 0.0 1.5e-87 295.2 0.0 1.0 1 0 0 1 1 1 1 Sec1 family HECT PF00632.25 CBZ28060.1 - 1.9e-34 119.5 0.0 4.1e-34 118.5 0.0 1.5 1 1 0 1 1 1 1 HECT-domain (ubiquitin-transferase) SPRY PF00622.28 CBZ28060.1 - 9.3e-14 51.6 0.0 1.6e-09 37.9 0.0 3.5 3 0 0 3 3 3 2 SPRY domain zf-RanBP PF00641.18 CBZ28060.1 - 1.1e-06 27.9 13.6 3.1e-05 23.2 2.5 2.8 1 1 1 2 2 2 2 Zn-finger in Ran binding protein and others fn3 PF00041.21 CBZ28061.1 - 7.2e-94 308.3 52.5 7.3e-05 23.0 0.2 38.4 41 4 0 41 41 41 21 Fibronectin type III domain Pur_ac_phosph_N PF16656.5 CBZ28061.1 - 9.4e-44 147.9 47.6 0.0049 17.4 0.8 28.6 30 1 0 30 30 30 12 Purple acid Phosphatase, N-terminal domain Interfer-bind PF09294.10 CBZ28061.1 - 1.3e-14 54.3 6.7 2.7 8.4 0.0 14.4 16 0 0 16 16 16 1 Interferon-alpha/beta receptor, fibronectin type III Glyco_hydro_36C PF16874.5 CBZ28061.1 - 0.0011 19.4 0.0 50 4.5 0.0 8.2 10 0 0 10 10 10 0 Glycosyl hydrolase family 36 C-terminal domain DUF2369 PF10179.9 CBZ28061.1 - 0.0029 18.0 3.6 76 3.8 0.0 7.6 10 0 0 10 10 10 0 Uncharacterised conserved protein (DUF2369) fn3_4 PF16794.5 CBZ28061.1 - 0.003 17.5 0.0 1.2 9.1 0.0 4.9 4 0 0 4 4 4 1 Fibronectin-III type domain Collagen_bind_2 PF12904.7 CBZ28061.1 - 0.008 16.1 0.0 13 5.9 0.0 6.1 9 0 0 9 9 9 1 Putative collagen-binding domain of a collagenase Y_Y_Y PF07495.13 CBZ28061.1 - 0.012 15.5 0.0 5.2 7.1 0.0 4.7 5 0 0 5 5 5 0 Y_Y_Y domain zf-primase PF09329.11 CBZ28062.1 - 4.7e-09 35.9 0.6 8.8e-09 35.0 0.6 1.5 1 0 0 1 1 1 1 Primase zinc finger Mcm10 PF09332.11 CBZ28062.1 - 3.7e-08 33.2 3.9 6.9e-08 32.3 3.9 1.3 1 0 0 1 1 1 1 Mcm10 replication factor Tim17 PF02466.19 CBZ28063.1 - 1.8e-09 37.9 1.1 6.8e-09 36.1 0.9 1.8 2 0 0 2 2 2 1 Tim17/Tim22/Tim23/Pmp24 family PhaP_Bmeg PF09602.10 CBZ28064.1 - 0.06 13.3 2.5 0.34 10.8 0.1 2.8 3 0 0 3 3 3 0 Polyhydroxyalkanoic acid inclusion protein (PhaP_Bmeg) BTB PF00651.31 CBZ28065.1 - 1.5e-10 41.3 0.3 0.0012 19.1 0.2 3.0 2 1 0 2 2 2 2 BTB/POZ domain MATH PF00917.26 CBZ28065.1 - 0.00012 22.2 0.0 0.00022 21.4 0.0 1.4 1 0 0 1 1 1 1 MATH domain JAB PF01398.21 CBZ28066.1 - 9.8e-16 57.8 0.3 1.3e-08 34.8 0.1 2.5 2 0 0 2 2 2 2 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Prok-JAB PF14464.6 CBZ28066.1 - 2.2e-09 37.1 0.2 2.2e-06 27.4 0.1 2.4 2 0 0 2 2 2 2 Prokaryotic homologs of the JAB domain Pkinase PF00069.25 CBZ28067.1 - 1e-43 149.7 0.0 1.3e-43 149.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ28067.1 - 5.7e-32 111.0 0.0 7.9e-32 110.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CBZ28067.1 - 0.00071 19.0 0.3 0.0024 17.3 0.3 1.7 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.14 CBZ28067.1 - 0.0046 16.4 0.1 0.0084 15.5 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family DUF2513 PF10711.9 CBZ28068.1 - 0.047 14.0 0.0 0.27 11.6 0.0 2.0 2 0 0 2 2 2 0 Hypothetical protein (DUF2513) RRM_1 PF00076.22 CBZ28068.1 - 0.16 11.8 0.0 0.35 10.7 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PsbW PF07123.12 CBZ28069.1 - 3.2 7.8 5.4 0.8 9.7 1.6 1.9 2 0 0 2 2 2 0 Photosystem II reaction centre W protein (PsbW) TackOD1 PF18551.1 CBZ28070.1 - 0.06 13.0 8.4 0.087 12.5 1.0 2.3 1 1 1 2 2 2 0 Thaumarchaeal output domain 1 Zn_Tnp_IS1 PF03811.13 CBZ28070.1 - 0.077 12.7 1.7 0.077 12.7 1.7 2.6 3 0 0 3 3 3 0 InsA N-terminal domain Stc1 PF12898.7 CBZ28070.1 - 0.13 12.8 12.7 0.15 12.6 0.9 2.9 1 1 2 3 3 3 0 Stc1 domain zf-RING_6 PF14835.6 CBZ28070.1 - 0.41 10.6 6.1 0.21 11.5 4.0 1.6 1 1 0 1 1 1 0 zf-RING of BARD1-type protein CDP-OH_P_transf PF01066.21 CBZ28071.1 - 3.5e-12 46.9 3.3 3.5e-12 46.9 3.3 2.8 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase PAC2 PF09754.9 CBZ28071.1 - 0.19 11.7 0.1 0.29 11.1 0.1 1.3 1 0 0 1 1 1 0 PAC2 family Filament PF00038.21 CBZ28072.1 - 0.0014 18.3 12.0 0.0014 18.3 12.0 8.7 3 2 3 7 7 7 1 Intermediate filament protein CC2-LZ PF16516.5 CBZ28072.1 - 0.0024 18.2 6.0 0.0024 18.2 6.0 15.1 9 3 6 17 17 17 2 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator HMMR_N PF15905.5 CBZ28072.1 - 0.0063 16.0 6.0 0.0063 16.0 6.0 9.7 5 3 4 9 9 9 4 Hyaluronan mediated motility receptor N-terminal SlyX PF04102.12 CBZ28072.1 - 0.11 13.1 0.1 0.11 13.1 0.1 20.8 14 6 5 19 19 19 0 SlyX RTBV_P46 PF06216.11 CBZ28072.1 - 4.1 6.2 6.4 0.48 9.2 0.7 2.3 2 0 0 2 2 2 0 Rice tungro bacilliform virus P46 protein MTCP1 PF08991.10 CBZ28074.1 - 0.00016 21.8 4.4 0.025 14.8 0.7 2.3 2 0 0 2 2 2 2 Mature-T-Cell Proliferation I type CHCH PF06747.13 CBZ28074.1 - 0.001 19.1 10.6 0.12 12.6 4.5 2.5 2 0 0 2 2 2 2 CHCH domain CX9C PF16860.5 CBZ28074.1 - 0.0079 16.2 2.4 0.0079 16.2 2.4 2.3 2 1 0 2 2 2 1 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, STI1 PF17830.1 CBZ28074.1 - 0.11 12.4 0.0 0.22 11.5 0.0 1.4 1 0 0 1 1 1 0 STI1 domain NHR2 PF08788.11 CBZ28074.1 - 0.2 11.4 4.4 0.27 11.0 4.0 1.5 1 1 0 1 1 1 0 NHR2 domain like COX6B PF02297.17 CBZ28074.1 - 4.8 7.5 10.6 0.64 10.3 6.3 1.9 2 1 0 2 2 2 0 Cytochrome oxidase c subunit VIb Pkinase PF00069.25 CBZ28075.1 - 2.1e-48 165.0 0.0 2.6e-48 164.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ28075.1 - 3.7e-28 98.5 0.0 5.3e-28 98.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase FYVE PF01363.21 CBZ28075.1 - 6.3e-09 35.8 14.5 1.4e-08 34.7 14.5 1.6 1 0 0 1 1 1 1 FYVE zinc finger Pkinase_fungal PF17667.1 CBZ28075.1 - 0.00036 19.4 0.0 0.00058 18.8 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 CBZ28075.1 - 0.0015 18.5 0.0 0.0056 16.6 0.0 1.8 1 1 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 CBZ28075.1 - 0.033 13.8 0.0 0.052 13.1 0.0 1.3 1 0 0 1 1 1 0 RIO1 family DnaJ PF00226.31 CBZ28076.1 - 1.5e-05 25.0 0.0 4.2e-05 23.6 0.0 1.8 1 0 0 1 1 1 1 DnaJ domain zf-LITAF-like PF10601.9 CBZ28076.1 - 0.012 15.9 13.3 0.068 13.4 8.1 2.5 2 0 0 2 2 2 0 LITAF-like zinc ribbon domain GEMIN8 PF15348.6 CBZ28076.1 - 0.81 9.9 10.9 0.5 10.6 2.6 2.4 2 0 0 2 2 2 0 Gemini of Cajal bodies-associated protein 8 TFIIA PF03153.13 CBZ28076.1 - 1.5 8.8 13.7 1.6 8.7 1.2 2.2 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit CDC27 PF09507.10 CBZ28076.1 - 1.6 8.1 34.5 1 8.7 15.7 2.2 2 0 0 2 2 2 0 DNA polymerase subunit Cdc27 Metallophos PF00149.28 CBZ28077.1 - 1.1e-34 120.8 0.0 1.8e-34 120.1 0.0 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase PPR PF01535.20 CBZ28078.1 - 0.0035 17.5 0.0 1.8 9.0 0.0 3.2 2 0 0 2 2 2 2 PPR repeat DUF4376 PF14301.6 CBZ28078.1 - 0.056 13.8 0.0 0.32 11.4 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4376) SET PF00856.28 CBZ28080.1 - 6.6e-14 52.6 0.0 6.9e-12 46.1 0.0 2.4 1 1 0 1 1 1 1 SET domain Dala_Dala_lig_C PF07478.13 CBZ28080.1 - 5.1e-13 49.0 0.0 8.7e-13 48.3 0.0 1.3 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 CBZ28080.1 - 0.0004 20.0 0.0 0.00066 19.3 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_4 PF13535.6 CBZ28080.1 - 0.096 12.3 0.1 0.4 10.2 0.0 2.0 2 1 0 2 2 2 0 ATP-grasp domain GARS_A PF01071.19 CBZ28080.1 - 0.17 11.6 0.0 0.3 10.8 0.0 1.3 1 0 0 1 1 1 0 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain Pkinase PF00069.25 CBZ28081.1 - 1.4e-44 152.5 0.0 2.2e-44 151.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ28081.1 - 1.5e-33 116.2 0.0 1.9e-33 115.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CBZ28081.1 - 0.0024 16.7 0.0 0.0035 16.2 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase TrmO_C PF18389.1 CBZ28081.1 - 0.011 15.8 0.0 0.027 14.6 0.0 1.6 1 0 0 1 1 1 0 TrmO C-terminal domain DUF1829 PF08862.10 CBZ28082.1 - 0.041 14.4 0.1 12 6.4 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function DUF1829 SYCE1 PF15233.6 CBZ28082.1 - 0.48 10.5 8.6 25 4.9 8.6 2.2 1 1 0 1 1 1 0 Synaptonemal complex central element protein 1 PqiA PF04403.13 CBZ28083.1 - 7.8e-12 45.3 25.0 1.1e-10 41.5 10.6 4.0 3 1 0 3 3 3 2 Paraquat-inducible protein A Golgin_A5 PF09787.9 CBZ28084.1 - 0.097 12.1 7.7 0.23 10.9 0.5 2.4 2 0 0 2 2 2 0 Golgin subfamily A member 5 Syntaxin-6_N PF09177.11 CBZ28084.1 - 1.4 9.5 4.6 16 6.2 0.2 2.9 2 0 0 2 2 2 0 Syntaxin 6, N-terminal FAD_binding_3 PF01494.19 CBZ28085.1 - 1.5e-11 44.1 0.0 4.8e-09 35.9 0.0 2.9 2 2 1 3 3 3 1 FAD binding domain NAD_binding_8 PF13450.6 CBZ28085.1 - 7.5e-07 29.3 0.0 2.3e-06 27.7 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 CBZ28085.1 - 0.00042 19.5 0.1 0.00079 18.6 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.27 CBZ28085.1 - 0.00059 20.3 0.0 0.0013 19.3 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 CBZ28085.1 - 0.0011 18.2 0.0 0.0031 16.8 0.0 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 CBZ28085.1 - 0.0012 18.5 0.0 0.0041 16.7 0.1 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 CBZ28085.1 - 0.014 14.5 0.4 0.041 12.9 0.0 2.0 3 0 0 3 3 3 0 Lycopene cyclase protein Pyr_redox_3 PF13738.6 CBZ28085.1 - 0.058 12.6 0.0 0.099 11.9 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 CBZ28085.1 - 0.074 12.3 0.0 0.11 11.7 0.0 1.2 1 0 0 1 1 1 0 Thi4 family DUF2798 PF11391.8 CBZ28086.1 - 0.13 12.3 0.1 0.29 11.2 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2798) zf-CSL PF05207.13 CBZ28087.1 - 3.7e-15 55.4 0.2 5.2e-15 54.9 0.2 1.2 1 0 0 1 1 1 1 CSL zinc finger Bacillus_HBL PF05791.11 CBZ28088.1 - 0.017 15.0 0.4 0.03 14.2 0.4 1.4 1 0 0 1 1 1 0 Bacillus haemolytic enterotoxin (HBL) CLZ PF16526.5 CBZ28088.1 - 0.039 14.3 0.3 0.11 12.9 0.3 1.8 1 0 0 1 1 1 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Hamartin PF04388.12 CBZ28088.1 - 1.9 7.0 8.7 2.3 6.8 8.7 1.1 1 0 0 1 1 1 0 Hamartin protein HECT PF00632.25 CBZ28089.1 - 2.6e-08 33.7 0.0 5.6e-05 22.8 0.0 2.8 3 0 0 3 3 3 2 HECT-domain (ubiquitin-transferase) CAP_N PF01213.19 CBZ28089.1 - 0.047 13.2 2.2 0.12 11.9 2.2 1.6 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal ATG16 PF08614.11 CBZ28090.1 - 0.011 16.0 8.3 0.011 16.0 8.3 5.3 1 1 4 5 5 5 0 Autophagy protein 16 (ATG16) RTT107_BRCT_5 PF16770.5 CBZ28090.1 - 0.028 14.3 0.0 0.1 12.5 0.0 2.0 1 0 0 1 1 1 0 Regulator of Ty1 transposition protein 107 BRCT domain Filament PF00038.21 CBZ28090.1 - 6.9 6.2 83.1 2.9 7.4 0.8 5.9 1 1 4 5 5 5 0 Intermediate filament protein ABC_membrane PF00664.23 CBZ28091.1 - 3e-95 319.0 30.2 7.9e-53 179.9 12.0 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 CBZ28091.1 - 2.5e-69 232.1 0.1 2.1e-35 122.2 0.0 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 CBZ28091.1 - 7.9e-13 48.3 0.5 1.4e-06 27.9 0.0 3.7 2 2 1 3 3 3 2 RecF/RecN/SMC N terminal domain Zeta_toxin PF06414.12 CBZ28091.1 - 5.2e-06 25.9 0.1 0.003 16.9 0.0 2.4 2 0 0 2 2 2 2 Zeta toxin RsgA_GTPase PF03193.16 CBZ28091.1 - 8.4e-06 25.8 0.0 0.2 11.5 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA_29 PF13555.6 CBZ28091.1 - 1.5e-05 24.6 0.4 0.14 12.0 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain ABC_ATPase PF09818.9 CBZ28091.1 - 0.00011 21.1 0.1 0.0063 15.4 0.1 2.3 2 0 0 2 2 2 1 Predicted ATPase of the ABC class AAA PF00004.29 CBZ28091.1 - 0.00012 22.5 2.0 0.57 10.6 0.3 3.9 2 2 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_23 PF13476.6 CBZ28091.1 - 0.00019 22.0 0.2 0.61 10.6 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.6 CBZ28091.1 - 0.00021 21.7 0.1 0.63 10.4 0.1 2.6 2 0 0 2 2 2 2 AAA ATPase domain AAA_15 PF13175.6 CBZ28091.1 - 0.00028 20.7 0.0 0.18 11.5 0.0 2.3 2 0 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.6 CBZ28091.1 - 0.00048 20.4 1.4 0.32 11.3 0.1 3.7 2 2 0 2 2 2 1 AAA domain AAA_25 PF13481.6 CBZ28091.1 - 0.0013 18.4 1.6 6.7 6.2 0.0 3.7 4 0 0 4 4 4 0 AAA domain Rad17 PF03215.15 CBZ28091.1 - 0.0013 18.7 0.1 0.2 11.5 0.0 2.6 2 0 0 2 2 2 1 Rad17 P-loop domain ATP-synt_ab PF00006.25 CBZ28091.1 - 0.0013 18.4 0.2 1.5 8.4 0.0 2.8 2 0 0 2 2 2 2 ATP synthase alpha/beta family, nucleotide-binding domain G-alpha PF00503.20 CBZ28091.1 - 0.0017 17.6 0.1 0.21 10.7 0.0 2.2 2 0 0 2 2 2 1 G-protein alpha subunit AAA_7 PF12775.7 CBZ28091.1 - 0.0019 17.7 0.1 0.41 10.1 0.0 2.4 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_5 PF07728.14 CBZ28091.1 - 0.0045 17.0 0.0 0.66 10.0 0.0 3.3 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) DUF87 PF01935.17 CBZ28091.1 - 0.0058 16.8 1.2 2.2 8.3 0.0 3.2 3 0 0 3 3 3 1 Helicase HerA, central domain RNA_helicase PF00910.22 CBZ28091.1 - 0.0075 16.6 0.3 7.4 7.0 0.1 3.1 2 0 0 2 2 2 0 RNA helicase MoaE PF02391.17 CBZ28091.1 - 0.009 16.3 0.7 0.19 12.0 0.0 3.1 4 0 0 4 4 2 1 MoaE protein Viral_helicase1 PF01443.18 CBZ28091.1 - 0.02 14.7 0.1 12 5.6 0.0 3.0 3 0 0 3 3 2 0 Viral (Superfamily 1) RNA helicase SbcCD_C PF13558.6 CBZ28091.1 - 0.071 13.4 6.5 15 5.9 0.8 4.3 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_18 PF13238.6 CBZ28091.1 - 0.09 13.3 0.0 12 6.4 0.0 2.7 2 0 0 2 2 2 0 AAA domain DUF815 PF05673.13 CBZ28091.1 - 0.13 11.4 0.0 11 5.1 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF815) NTPase_1 PF03266.15 CBZ28091.1 - 0.17 11.8 2.4 30 4.5 0.1 3.4 2 1 0 3 3 3 0 NTPase AAA_21 PF13304.6 CBZ28091.1 - 0.2 11.4 0.1 6.2 6.5 0.0 2.6 3 0 0 3 3 2 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_28 PF13521.6 CBZ28091.1 - 0.2 11.9 1.8 6.2 7.0 0.1 2.8 3 0 0 3 3 2 0 AAA domain MMR_HSR1 PF01926.23 CBZ28091.1 - 0.24 11.5 0.9 29 4.8 0.0 3.0 3 0 0 3 3 2 0 50S ribosome-binding GTPase DEAD PF00270.29 CBZ28091.1 - 0.41 10.4 3.5 1.4 8.6 0.3 3.0 2 2 0 2 2 2 0 DEAD/DEAH box helicase NB-ARC PF00931.22 CBZ28091.1 - 0.57 9.3 2.3 11 5.1 0.0 2.6 3 0 0 3 3 3 0 NB-ARC domain 7TM_GPCR_Srh PF10318.9 CBZ28091.1 - 2 7.4 13.4 0.014 14.5 0.9 2.8 3 0 0 3 3 3 0 Serpentine type 7TM GPCR chemoreceptor Srh CPBP PF02517.16 CBZ28093.1 - 6.4e-20 71.3 1.2 1.4e-19 70.3 0.2 1.9 2 0 0 2 2 2 1 CPBP intramembrane metalloprotease Glucosamine_iso PF01182.20 CBZ28094.1 - 5e-52 177.0 0.0 5.8e-52 176.8 0.0 1.0 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase AA_kinase PF00696.28 CBZ28095.1 - 7.7e-40 137.0 0.2 9.5e-40 136.7 0.2 1.0 1 0 0 1 1 1 1 Amino acid kinase family TPR_2 PF07719.17 CBZ28096.1 - 0.00039 20.3 2.3 1 9.6 0.0 3.8 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_20 PF14561.6 CBZ28096.1 - 0.00083 19.6 0.2 0.046 14.0 0.0 3.4 3 2 1 4 4 4 1 Tetratricopeptide repeat TPR_19 PF14559.6 CBZ28096.1 - 0.001 19.5 2.2 2.6 8.6 0.0 4.3 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_14 PF13428.6 CBZ28096.1 - 0.0013 19.4 3.8 0.73 10.8 0.0 4.1 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_6 PF13174.6 CBZ28096.1 - 0.017 15.7 3.8 1.3 9.8 0.1 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_16 PF13432.6 CBZ28096.1 - 0.022 15.4 2.2 30 5.4 0.2 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.6 CBZ28096.1 - 0.055 13.8 0.4 19 5.6 0.1 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat Thioredoxin PF00085.20 CBZ28096.1 - 0.15 12.1 0.0 0.3 11.1 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin Meckelin PF09773.9 CBZ28097.1 - 4.3e-243 809.1 5.6 6.7e-243 808.5 5.6 1.3 1 0 0 1 1 1 1 Meckelin (Transmembrane protein 67) MerT PF02411.15 CBZ28097.1 - 0.02 14.9 0.3 12 5.9 0.0 3.1 2 0 0 2 2 2 0 MerT mercuric transport protein MSC PF09402.10 CBZ28097.1 - 3.3 7.1 7.1 47 3.3 0.0 2.5 2 1 0 2 2 2 0 Man1-Src1p-C-terminal domain TGT PF01702.18 CBZ28098.1 - 1.2e-28 100.3 0.0 2e-27 96.3 0.0 1.9 1 1 0 1 1 1 1 Queuine tRNA-ribosyltransferase Peptidase_M48_N PF16491.5 CBZ28099.1 - 4.4e-41 140.8 3.0 8.3e-41 139.9 3.0 1.4 1 0 0 1 1 1 1 CAAX prenyl protease N-terminal, five membrane helices Peptidase_M48 PF01435.18 CBZ28099.1 - 1.8e-40 138.9 0.1 5.4e-40 137.3 0.0 1.7 2 0 0 2 2 2 1 Peptidase family M48 Peptidase_M56 PF05569.11 CBZ28099.1 - 0.055 12.7 0.6 0.099 11.8 0.1 1.7 2 0 0 2 2 2 0 BlaR1 peptidase M56 HapK PF11639.8 CBZ28099.1 - 0.14 12.6 0.0 0.31 11.5 0.0 1.5 1 0 0 1 1 1 0 REDY-like protein HapK DEAD PF00270.29 CBZ28100.1 - 4.6e-39 134.0 0.2 7.9e-39 133.2 0.2 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CBZ28100.1 - 3e-23 82.3 0.1 2.5e-20 72.9 0.0 3.6 2 1 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 CBZ28100.1 - 4.5e-08 33.3 0.0 1.2e-07 31.8 0.0 1.7 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DUF4217 PF13959.6 CBZ28100.1 - 4.9e-07 29.9 0.9 2e-06 27.9 0.2 2.4 3 0 0 3 3 3 1 Domain of unknown function (DUF4217) AAA_22 PF13401.6 CBZ28100.1 - 0.13 12.5 2.1 2 8.7 0.9 3.1 2 1 0 2 2 2 0 AAA domain CcmD PF04995.14 CBZ28101.1 - 0.22 11.7 0.4 0.22 11.7 0.4 1.7 2 0 0 2 2 2 0 Heme exporter protein D (CcmD) p450 PF00067.22 CBZ28104.1 - 3.4e-54 184.3 0.0 4.5e-54 183.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 RNA_pol_L PF01193.24 CBZ28104.1 - 0.085 12.3 1.9 0.11 11.9 0.0 2.1 2 0 0 2 2 2 0 RNA polymerase Rpb3/Rpb11 dimerisation domain Pkinase PF00069.25 CBZ28105.1 - 1.7e-67 227.6 0.0 2.4e-67 227.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ28105.1 - 4.3e-27 95.0 0.0 6.9e-27 94.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase PUL PF08324.11 CBZ28105.1 - 0.013 14.8 0.0 0.93 8.7 0.0 2.2 2 0 0 2 2 2 0 PUL domain RINGv PF12906.7 CBZ28107.1 - 3.5e-10 39.8 11.9 6.9e-10 38.9 11.9 1.5 1 0 0 1 1 1 1 RING-variant domain zf-RING_4 PF14570.6 CBZ28107.1 - 0.55 10.1 9.6 1.4 8.8 9.6 1.7 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain WW PF00397.26 CBZ28108.1 - 2.5e-11 43.5 1.7 2.5e-11 43.5 1.7 1.7 2 0 0 2 2 2 1 WW domain zf_CCCH_4 PF18345.1 CBZ28108.1 - 1.6e-06 28.0 3.6 3.1e-06 27.0 3.6 1.5 1 0 0 1 1 1 1 Zinc finger domain zf-CCCH PF00642.24 CBZ28108.1 - 2.2e-06 27.4 0.7 3.5e-06 26.8 0.7 1.3 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 CBZ28108.1 - 1.8e-05 24.4 1.6 3.4e-05 23.5 1.6 1.5 1 0 0 1 1 1 1 CCCH-type zinc finger Torus PF16131.5 CBZ28108.1 - 0.0073 17.0 0.1 0.008 16.9 0.1 1.3 1 0 0 1 1 1 1 Torus domain DUF3251 PF11622.8 CBZ28109.1 - 0.024 14.3 0.0 0.15 11.7 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3251) Herpes_BLRF2 PF05812.12 CBZ28109.1 - 0.065 13.4 0.3 0.12 12.5 0.3 1.5 1 0 0 1 1 1 0 Herpesvirus BLRF2 protein Torus PF16131.5 CBZ28110.1 - 5.9e-07 30.2 0.1 1.3e-06 29.0 0.1 1.5 1 0 0 1 1 1 1 Torus domain zf_CCCH_4 PF18345.1 CBZ28110.1 - 7e-07 29.1 2.5 9.9e-07 28.6 2.5 1.2 1 0 0 1 1 1 1 Zinc finger domain zf-CCCH_4 PF18044.1 CBZ28110.1 - 5.2e-06 26.1 1.3 7.2e-06 25.7 1.3 1.2 1 0 0 1 1 1 1 CCCH-type zinc finger zf-CCCH PF00642.24 CBZ28110.1 - 0.0067 16.3 0.3 0.0099 15.8 0.3 1.2 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.6 CBZ28110.1 - 0.0071 16.8 2.5 0.011 16.2 2.5 1.3 1 0 0 1 1 1 1 RNA-binding, Nab2-type zinc finger SET PF00856.28 CBZ28111.1 - 2.1e-13 51.0 0.0 9.7e-13 48.9 0.0 1.8 1 1 0 1 1 1 1 SET domain OSTMP1 PF09777.9 CBZ28111.1 - 0.0021 17.5 0.2 0.0031 16.9 0.2 1.2 1 0 0 1 1 1 1 Osteopetrosis-associated transmembrane protein 1 precursor Proteasome PF00227.26 CBZ28114.1 - 5.3e-44 150.0 0.1 7e-44 149.6 0.1 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 CBZ28114.1 - 1.2e-08 34.5 0.1 1.2e-08 34.5 0.1 1.7 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature Inhibitor_I36 PF03995.13 CBZ28115.1 - 0.0016 18.3 0.3 0.64 10.0 0.1 2.9 3 0 0 3 3 3 2 Peptidase inhibitor family I36 Torus PF16131.5 CBZ28115.1 - 0.0021 18.8 0.1 0.0057 17.3 0.1 1.7 1 0 0 1 1 1 1 Torus domain VIT1 PF01988.19 CBZ28116.1 - 1.1e-51 175.8 4.1 1.6e-51 175.3 4.1 1.2 1 0 0 1 1 1 1 VIT family SET PF00856.28 CBZ28117.1 - 0.2 12.0 0.0 0.23 11.8 0.0 1.3 1 1 0 1 1 1 0 SET domain DUF3295 PF11702.8 CBZ28118.1 - 0.0081 15.6 0.3 0.25 10.6 0.2 2.0 2 0 0 2 2 2 2 Protein of unknown function (DUF3295) XPG_I PF00867.18 CBZ28120.1 - 2e-31 108.2 0.0 3.8e-31 107.3 0.0 1.5 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.17 CBZ28120.1 - 1.3e-26 93.0 0.0 2.7e-26 92.0 0.0 1.5 1 0 0 1 1 1 1 XPG N-terminal domain 5_3_exonuc PF01367.20 CBZ28120.1 - 1.9e-06 28.3 0.0 1.5e-05 25.5 0.0 2.2 2 0 0 2 2 2 1 5'-3' exonuclease, C-terminal SAM fold 5_3_exonuc_N PF02739.16 CBZ28120.1 - 0.0078 16.1 0.0 0.017 15.1 0.0 1.5 1 1 0 1 1 1 1 5'-3' exonuclease, N-terminal resolvase-like domain XRN_N PF03159.18 CBZ28120.1 - 0.0081 15.6 0.0 0.0094 15.4 0.0 1.2 1 0 0 1 1 1 1 XRN 5'-3' exonuclease N-terminus DUF3043 PF11241.8 CBZ28120.1 - 0.09 12.8 1.4 0.17 11.9 1.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3043) TPR_16 PF13432.6 CBZ28120.1 - 0.16 12.7 1.1 1.5 9.5 0.0 2.6 3 0 0 3 3 3 0 Tetratricopeptide repeat PBP1_TM PF14812.6 CBZ28122.1 - 0.089 13.2 2.5 27 5.2 0.1 3.9 3 0 0 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal MAJIN PF15077.6 CBZ28122.1 - 1.1 9.0 11.1 2.3 7.9 3.0 3.8 2 1 1 3 3 3 0 Membrane-anchored junction protein HNH_2 PF13391.6 CBZ28123.1 - 0.13 12.4 0.0 0.2 11.8 0.0 1.2 1 0 0 1 1 1 0 HNH endonuclease PP-binding PF00550.25 CBZ28124.1 - 3e-10 40.3 0.1 3.9e-10 39.9 0.1 1.2 1 0 0 1 1 1 1 Phosphopantetheine attachment site CdiI_3 PF18616.1 CBZ28124.1 - 0.095 12.6 0.0 0.32 10.9 0.0 1.8 1 1 0 1 1 1 0 CDI immunity proteins MM_CoA_mutase PF01642.22 CBZ28125.1 - 1.2e-229 763.1 1.0 1.5e-229 762.9 1.0 1.1 1 0 0 1 1 1 1 Methylmalonyl-CoA mutase B12-binding PF02310.19 CBZ28125.1 - 2.4e-12 47.0 0.1 6.4e-12 45.6 0.1 1.7 1 0 0 1 1 1 1 B12 binding domain FtsK_SpoIIIE PF01580.18 CBZ28125.1 - 0.022 14.1 0.9 0.36 10.2 0.2 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family HisG_C PF08029.11 CBZ28125.1 - 0.054 13.6 0.0 0.15 12.2 0.0 1.8 1 0 0 1 1 1 0 HisG, C-terminal domain Histone_HNS PF00816.21 CBZ28125.1 - 1.6 9.6 3.3 12 6.8 1.3 3.3 4 0 0 4 4 4 0 H-NS histone family TIP120 PF08623.10 CBZ28126.1 - 2.7e-09 37.0 0.7 1.1e-08 35.0 0.0 2.4 2 0 0 2 2 2 1 TATA-binding protein interacting (TIP20) DUF4259 PF14078.6 CBZ28126.1 - 0.05 14.3 0.1 1.6 9.5 0.0 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4259) TSNAXIP1_N PF15739.5 CBZ28128.1 - 7.3e-20 71.4 4.8 7.3e-20 71.4 4.8 2.6 2 0 0 2 2 2 1 Translin-associated factor X-interacting N-terminus Atg14 PF10186.9 CBZ28128.1 - 4.7 6.2 13.9 11 5.0 13.9 1.5 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 RRM_1 PF00076.22 CBZ28130.1 - 3.2e-14 52.5 0.0 1.1e-07 31.6 0.0 2.7 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) AAA PF00004.29 CBZ28131.1 - 4.6e-36 124.2 0.0 4.3e-35 121.0 0.0 2.2 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 CBZ28131.1 - 9.6e-11 42.4 0.1 0.00022 21.7 0.0 3.5 2 2 0 3 3 3 2 AAA ATPase domain AAA_lid_3 PF17862.1 CBZ28131.1 - 1.3e-06 28.1 0.1 3.5e-06 26.7 0.1 1.8 1 0 0 1 1 1 1 AAA+ lid domain Rad17 PF03215.15 CBZ28131.1 - 0.00039 20.4 0.0 0.0092 15.9 0.0 2.2 2 0 0 2 2 2 1 Rad17 P-loop domain AAA_5 PF07728.14 CBZ28131.1 - 0.0016 18.5 0.0 0.011 15.8 0.0 2.4 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) DUF815 PF05673.13 CBZ28131.1 - 0.0035 16.5 0.0 1.8 7.6 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF815) RNA_helicase PF00910.22 CBZ28131.1 - 0.0062 16.9 0.0 0.28 11.6 0.0 2.4 2 0 0 2 2 2 1 RNA helicase AAA_7 PF12775.7 CBZ28131.1 - 0.035 13.6 0.0 1.1 8.7 0.0 2.6 3 0 0 3 3 3 0 P-loop containing dynein motor region AAA_33 PF13671.6 CBZ28131.1 - 0.05 13.8 0.0 0.12 12.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.6 CBZ28131.1 - 0.07 13.2 0.0 0.64 10.1 0.0 2.3 2 0 0 2 2 2 0 AAA domain RuvB_N PF05496.12 CBZ28131.1 - 0.07 12.9 0.0 0.21 11.3 0.0 1.8 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain ATPase_2 PF01637.18 CBZ28131.1 - 0.092 12.6 0.0 0.97 9.3 0.0 2.4 2 1 1 3 3 3 0 ATPase domain predominantly from Archaea Herpes_UL49_5 PF05702.11 CBZ28132.1 - 0.024 14.7 0.0 0.041 14.0 0.0 1.3 1 0 0 1 1 1 0 Herpesvirus UL49.5 envelope/tegument protein Nup96 PF12110.8 CBZ28133.1 - 2e-35 122.4 0.0 3.2e-35 121.7 0.0 1.3 1 0 0 1 1 1 1 Nuclear protein 96 Nucleoporin2 PF04096.14 CBZ28133.1 - 2.2e-13 50.5 0.0 3.9e-13 49.8 0.0 1.4 1 0 0 1 1 1 1 Nucleoporin autopeptidase APG9 PF04109.16 CBZ28134.1 - 5.8e-61 207.0 4.9 1.1e-60 206.0 4.9 1.4 1 1 0 1 1 1 1 Autophagy protein Apg9 DUF3525 PF12039.8 CBZ28134.1 - 0.096 11.4 0.3 0.15 10.7 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3525) NPHI_C PF08469.10 CBZ28135.1 - 0.12 12.4 0.4 0.15 12.0 0.4 1.2 1 0 0 1 1 1 0 Nucleoside triphosphatase I C-terminal DnaJ PF00226.31 CBZ28136.1 - 6e-25 87.1 0.6 1e-24 86.4 0.6 1.4 1 0 0 1 1 1 1 DnaJ domain PfkB PF00294.24 CBZ28137.1 - 4.6e-69 233.0 0.1 5.3e-69 232.8 0.1 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.12 CBZ28137.1 - 2.1e-09 37.1 0.0 3e-09 36.6 0.0 1.2 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase Mur_ligase PF01225.25 CBZ28137.1 - 0.057 13.7 0.0 0.25 11.7 0.0 2.3 1 1 0 1 1 1 0 Mur ligase family, catalytic domain Gly_reductase PF09338.11 CBZ28137.1 - 0.3 9.4 2.3 0.48 8.7 0.2 1.9 2 0 0 2 2 2 0 Glycine/sarcosine/betaine reductase component B subunits Vps53_N PF04100.12 CBZ28138.1 - 0.0082 15.1 0.9 0.013 14.5 0.9 1.2 1 0 0 1 1 1 1 Vps53-like, N-terminal AT_hook PF02178.19 CBZ28138.1 - 1.9 8.6 9.0 0.18 11.7 2.1 3.3 2 0 0 2 2 2 0 AT hook motif Brix PF04427.18 CBZ28140.1 - 2e-27 96.6 0.1 3.7e-27 95.7 0.1 1.4 1 0 0 1 1 1 1 Brix domain Vasohibin PF14822.6 CBZ28141.1 - 6e-48 163.2 0.0 9.2e-48 162.6 0.0 1.2 1 0 0 1 1 1 1 Vasohibin ABC_membrane_2 PF06472.15 CBZ28142.1 - 3.2e-25 89.1 0.1 6.2e-25 88.1 0.1 1.4 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 ABC_tran PF00005.27 CBZ28142.1 - 3.4e-15 56.7 0.0 8.4e-15 55.5 0.0 1.7 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 CBZ28142.1 - 4.6e-08 32.8 0.1 5.8e-07 29.2 0.1 2.1 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain NACHT PF05729.12 CBZ28142.1 - 0.00014 21.8 0.0 0.00029 20.8 0.0 1.6 1 1 0 1 1 1 1 NACHT domain AAA_21 PF13304.6 CBZ28142.1 - 0.00022 21.1 0.0 0.03 14.2 0.0 2.3 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 CBZ28142.1 - 0.0014 18.9 0.1 1.4 9.2 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_15 PF13175.6 CBZ28142.1 - 0.0026 17.5 0.0 0.0069 16.1 0.0 1.6 2 0 0 2 2 2 1 AAA ATPase domain ABC_membrane PF00664.23 CBZ28142.1 - 0.0028 17.4 0.8 0.0048 16.6 0.8 1.4 1 0 0 1 1 1 1 ABC transporter transmembrane region AAA_23 PF13476.6 CBZ28142.1 - 0.004 17.7 0.0 0.0087 16.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 CBZ28142.1 - 0.047 14.1 0.0 0.11 12.8 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain HTH_43 PF09904.9 CBZ28142.1 - 0.073 13.0 0.1 0.19 11.7 0.1 1.7 1 0 0 1 1 1 0 Winged helix-turn helix DUF2659 PF10858.8 CBZ28142.1 - 0.081 12.6 0.1 0.14 11.8 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2659) AAA_29 PF13555.6 CBZ28142.1 - 0.12 12.1 0.0 0.3 10.9 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain SbcCD_C PF13558.6 CBZ28142.1 - 0.13 12.5 0.0 0.41 10.9 0.0 1.8 1 0 0 1 1 1 0 Putative exonuclease SbcCD, C subunit Helo_like_N PF17111.5 CBZ28142.1 - 0.23 10.8 0.9 3.5 7.0 0.1 2.4 2 0 0 2 2 2 0 Fungal N-terminal domain of STAND proteins DASH_Dam1 PF08653.10 CBZ28142.1 - 0.49 10.2 3.2 17 5.3 0.2 2.8 2 0 0 2 2 2 0 DASH complex subunit Dam1 DUF5602 PF18197.1 CBZ28143.1 - 0.019 15.4 0.2 0.41 11.2 0.0 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF5602) Peptidase_C2 PF00648.21 CBZ28144.1 - 9.1e-65 218.6 0.0 2.7e-32 112.0 0.0 2.4 2 0 0 2 2 2 2 Calpain family cysteine protease Calpain_III PF01067.22 CBZ28144.1 - 1.6e-11 44.7 0.0 2.9e-05 24.3 0.0 3.4 3 0 0 3 3 3 2 Calpain large subunit, domain III DUF3563 PF12086.8 CBZ28144.1 - 0.0021 17.8 7.3 47 3.8 0.1 5.6 5 0 0 5 5 5 0 Protein of unknown function (DUF3563) DHNA PF04038.12 CBZ28144.1 - 0.069 13.7 0.0 0.28 11.7 0.0 2.0 2 0 0 2 2 2 0 Dihydroneopterin aldolase Phage_HK97_TLTM PF06120.11 CBZ28144.1 - 3.6 6.7 7.1 0.22 10.7 0.4 2.3 2 0 0 2 2 2 0 Tail length tape measure protein Peptidase_C2 PF00648.21 CBZ28146.1 - 1.7e-90 303.1 0.0 3.3e-34 118.3 0.0 3.3 3 0 0 3 3 3 3 Calpain family cysteine protease Calpain_III PF01067.22 CBZ28146.1 - 8e-13 48.8 0.0 0.00023 21.4 0.0 3.9 3 0 0 3 3 3 2 Calpain large subunit, domain III Radial_spoke_3 PF06098.11 CBZ28147.1 - 7e-109 363.5 26.4 8.3e-109 363.3 26.4 1.0 1 0 0 1 1 1 1 Radial spoke protein 3 G2BR PF18442.1 CBZ28148.1 - 0.034 13.8 1.5 0.079 12.6 1.5 1.6 1 0 0 1 1 1 0 E3 gp78 Ube2g2-binding region (G2BR) Amastin PF07344.11 CBZ28149.1 - 5.3e-09 36.1 9.5 5.3e-09 36.1 9.5 1.9 1 1 1 2 2 2 1 Amastin surface glycoprotein Rep_fac_C PF08542.11 CBZ28150.1 - 3.2e-18 65.9 0.0 2.8e-17 62.9 0.0 2.3 2 0 0 2 2 2 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.6 CBZ28150.1 - 3.9e-12 46.3 0.0 4.1e-11 42.9 0.0 2.1 1 1 0 1 1 1 1 DNA polymerase III, delta subunit AAA PF00004.29 CBZ28150.1 - 2.2e-11 44.3 0.1 7.7e-11 42.5 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 CBZ28150.1 - 1.1e-07 31.9 0.0 2.3e-07 30.9 0.0 1.4 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_22 PF13401.6 CBZ28150.1 - 5.1e-07 30.1 0.0 1.4e-06 28.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 CBZ28150.1 - 2.9e-05 23.5 0.1 0.0013 18.2 0.0 2.2 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_16 PF13191.6 CBZ28150.1 - 5.5e-05 23.6 1.2 0.0014 19.0 1.2 2.5 1 1 0 1 1 1 1 AAA ATPase domain AAA_assoc_2 PF16193.5 CBZ28150.1 - 7.1e-05 23.1 0.0 0.00016 22.0 0.0 1.7 1 0 0 1 1 1 1 AAA C-terminal domain DNA_pol3_delta PF06144.13 CBZ28150.1 - 0.00019 21.3 0.0 0.00036 20.4 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase III, delta subunit RuvB_N PF05496.12 CBZ28150.1 - 0.0002 21.1 0.1 0.00069 19.4 0.0 1.9 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_24 PF13479.6 CBZ28150.1 - 0.00048 19.9 0.0 0.00083 19.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 CBZ28150.1 - 0.00088 19.0 0.2 0.0026 17.5 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 CBZ28150.1 - 0.0011 19.4 0.1 0.0032 17.8 0.1 1.8 1 1 0 1 1 1 1 AAA domain AAA_11 PF13086.6 CBZ28150.1 - 0.0073 16.1 0.0 0.01 15.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.6 CBZ28150.1 - 0.0093 15.6 0.5 0.028 14.0 0.3 2.1 2 1 0 2 2 2 1 AAA domain AAA_5 PF07728.14 CBZ28150.1 - 0.014 15.4 0.0 0.33 10.9 0.0 2.4 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) DUF2075 PF09848.9 CBZ28150.1 - 0.015 14.6 0.0 0.022 14.0 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) RNA_helicase PF00910.22 CBZ28150.1 - 0.029 14.8 0.0 0.09 13.2 0.0 1.9 2 0 0 2 2 1 0 RNA helicase AAA_14 PF13173.6 CBZ28150.1 - 0.048 13.7 0.0 0.23 11.5 0.0 2.0 1 1 0 1 1 1 0 AAA domain AAA_18 PF13238.6 CBZ28150.1 - 0.065 13.8 0.0 0.14 12.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 CBZ28150.1 - 0.089 13.0 0.2 0.3 11.2 0.1 1.9 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 CBZ28150.1 - 0.1 12.3 0.0 0.2 11.4 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein Pkinase PF00069.25 CBZ28151.1 - 6.6e-62 209.3 0.0 7.5e-62 209.1 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ28151.1 - 1.3e-26 93.5 0.0 1.7e-26 93.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CBZ28151.1 - 0.0097 14.7 0.0 0.023 13.5 0.0 1.5 2 0 0 2 2 2 1 Fungal protein kinase APH PF01636.23 CBZ28151.1 - 0.011 15.7 0.1 0.022 14.7 0.1 1.5 1 1 0 1 1 1 0 Phosphotransferase enzyme family FTA2 PF13095.6 CBZ28151.1 - 0.044 13.4 0.0 6.9 6.2 0.0 2.3 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Lambda_Kil PF06301.11 CBZ28151.1 - 0.045 13.4 0.1 0.083 12.5 0.1 1.4 1 0 0 1 1 1 0 Bacteriophage lambda Kil protein zf-RING_2 PF13639.6 CBZ28152.1 - 4.1e-09 36.6 7.9 4.1e-09 36.6 7.9 2.4 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.25 CBZ28152.1 - 4.7e-07 29.6 7.2 4.7e-07 29.6 7.2 2.3 3 0 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 CBZ28152.1 - 1.6e-05 24.6 5.2 1.6e-05 24.6 5.2 2.7 2 1 0 2 2 2 1 Prokaryotic RING finger family 4 zf-C3HC4_3 PF13920.6 CBZ28152.1 - 1.8e-05 24.5 5.5 1.8e-05 24.5 5.5 2.8 2 1 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CBZ28152.1 - 2.8e-05 24.0 6.4 2.8e-05 24.0 6.4 2.7 2 1 0 2 2 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 CBZ28152.1 - 8.5e-05 22.5 5.6 8.5e-05 22.5 5.6 2.5 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 CBZ28152.1 - 8.9e-05 22.3 6.8 8.9e-05 22.3 6.8 2.6 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 CBZ28152.1 - 0.00098 19.4 8.6 0.00098 19.4 8.6 2.9 2 1 0 2 2 2 1 RING-H2 zinc finger domain zf-UDP PF14569.6 CBZ28152.1 - 0.0011 19.0 2.2 0.0011 19.0 2.2 2.4 2 0 0 2 2 2 1 Zinc-binding RING-finger zf-ANAPC11 PF12861.7 CBZ28152.1 - 0.024 14.7 1.8 0.024 14.7 1.8 2.3 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_4 PF15227.6 CBZ28152.1 - 0.03 14.5 5.0 0.03 14.5 5.0 2.7 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-RING_11 PF17123.5 CBZ28152.1 - 0.036 13.8 3.4 0.11 12.2 3.4 1.9 1 0 0 1 1 1 0 RING-like zinc finger CbiM PF01891.16 CBZ28152.1 - 0.051 13.4 0.0 0.092 12.6 0.0 1.3 1 0 0 1 1 1 0 Cobalt uptake substrate-specific transmembrane region zf-RING_6 PF14835.6 CBZ28152.1 - 0.32 10.9 3.3 0.92 9.4 3.3 1.8 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-FPG_IleRS PF06827.14 CBZ28152.1 - 3.2 7.7 5.5 38 4.3 0.1 3.7 3 0 0 3 3 3 0 Zinc finger found in FPG and IleRS zf-RING_4 PF14570.6 CBZ28152.1 - 4.8 7.1 20.8 0.029 14.2 7.1 2.7 2 1 0 2 2 2 0 RING/Ubox like zinc-binding domain SART-1 PF03343.13 CBZ28152.1 - 8 4.9 16.3 0.16 10.5 9.5 1.5 2 0 0 2 2 2 0 SART-1 family ANAPC4_WD40 PF12894.7 CBZ28153.1 - 1.5e-07 31.7 0.0 0.13 12.6 0.0 3.6 3 0 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 CBZ28153.1 - 1e-05 26.1 1.3 8.7 7.4 0.0 4.7 4 0 0 4 4 4 3 WD domain, G-beta repeat LisH PF08513.11 CBZ28153.1 - 0.0018 18.1 0.1 0.0034 17.3 0.1 1.5 1 0 0 1 1 1 1 LisH LisH_TPL PF17814.1 CBZ28153.1 - 0.064 12.9 0.1 0.13 11.9 0.1 1.5 1 0 0 1 1 1 0 LisH-like dimerisation domain DUF4471 PF14740.6 CBZ28154.1 - 1.2e-69 234.9 0.0 2.5e-69 233.9 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4471) DUF4470 PF14737.6 CBZ28154.1 - 6.5e-16 58.3 0.0 4.2e-15 55.7 0.0 2.1 1 1 0 1 1 1 1 Domain of unknown function (DUF4470) MSA-2c PF12238.8 CBZ28154.1 - 4.9 7.1 5.5 10 6.0 5.5 1.5 1 0 0 1 1 1 0 Merozoite surface antigen 2c Pmp3 PF01679.17 CBZ28157.1 - 6.7 7.0 7.5 1.3 9.3 2.9 2.3 2 0 0 2 2 2 0 Proteolipid membrane potential modulator MRP-S28 PF10213.9 CBZ28158.1 - 0.00042 20.7 0.0 0.0013 19.2 0.0 1.8 1 0 0 1 1 1 1 Mitochondrial ribosomal subunit protein Snapin_Pallidin PF14712.6 CBZ28159.1 - 0.021 15.2 0.4 0.052 14.0 0.4 1.6 1 0 0 1 1 1 0 Snapin/Pallidin YjbH PF06082.11 CBZ28159.1 - 0.55 9.0 5.4 0.079 11.8 0.8 1.7 2 0 0 2 2 2 0 Exopolysaccharide biosynthesis protein YbjH DUF5075 PF16825.5 CBZ28161.1 - 6.3e-08 32.5 6.6 1.6e-07 31.2 6.6 1.7 1 1 0 1 1 1 1 IGP family C-type lectin domain Mucin PF01456.17 CBZ28161.1 - 9.5e-07 28.9 44.6 2.7e-06 27.4 44.6 1.8 1 0 0 1 1 1 1 Mucin-like glycoprotein AJAP1_PANP_C PF15298.6 CBZ28161.1 - 0.026 14.7 21.0 0.063 13.5 21.0 1.6 1 0 0 1 1 1 0 AJAP1/PANP C-terminus RIFIN PF02009.16 CBZ28161.1 - 0.14 12.0 0.2 0.22 11.4 0.2 1.3 1 0 0 1 1 1 0 Rifin Aa_trans PF01490.18 CBZ28162.1 - 6e-54 183.3 33.1 7.6e-54 183.0 33.1 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Aa_trans PF01490.18 CBZ28163.1 - 3.6e-45 154.4 35.8 4.5e-45 154.1 35.8 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 CBZ28163.1 - 2.1e-09 36.9 20.0 2.1e-09 36.9 20.0 1.6 2 0 0 2 2 2 1 Tryptophan/tyrosine permease family DUF2207 PF09972.9 CBZ28163.1 - 0.0071 15.2 0.0 0.0071 15.2 0.0 2.9 2 1 0 3 3 3 1 Predicted membrane protein (DUF2207) VIT1 PF01988.19 CBZ28163.1 - 0.099 12.5 0.1 0.099 12.5 0.1 3.2 3 0 0 3 3 3 0 VIT family Ac76 PF05814.11 CBZ28163.1 - 2.3 8.3 6.0 0.76 9.8 0.6 2.4 2 0 0 2 2 2 0 Orf76 (Ac76) LRR_4 PF12799.7 CBZ28164.1 - 0.01 16.2 0.5 0.048 14.1 0.2 2.5 2 1 1 3 3 3 0 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 CBZ28164.1 - 0.016 15.2 0.4 4.8 7.5 0.0 3.7 4 0 0 4 4 4 0 Leucine Rich repeat LRR_8 PF13855.6 CBZ28164.1 - 0.49 10.2 4.2 1.7 8.5 0.2 2.9 3 0 0 3 3 3 0 Leucine rich repeat UBA PF00627.31 CBZ28167.1 - 6e-10 38.8 0.3 1.5e-09 37.5 0.3 1.7 1 0 0 1 1 1 1 UBA/TS-N domain UBA_4 PF14555.6 CBZ28167.1 - 0.045 13.6 0.0 0.1 12.4 0.0 1.6 1 0 0 1 1 1 0 UBA-like domain Alpha_Helical PF18489.1 CBZ28167.1 - 0.14 12.4 1.3 10 6.3 0.1 2.4 1 1 1 2 2 2 0 Alpha helical domain NAD_binding_1 PF00175.21 CBZ28168.1 - 5.2e-19 68.9 0.0 9.4e-19 68.1 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 CBZ28168.1 - 8.3e-15 55.0 0.0 1.3e-14 54.4 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.12 CBZ28168.1 - 0.00028 21.0 0.0 0.001 19.2 0.0 1.8 2 0 0 2 2 2 1 Ferric reductase NAD binding domain Oxidored_q6 PF01058.22 CBZ28169.1 - 2.8e-19 69.3 0.1 3.7e-19 68.9 0.1 1.2 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase, 20 Kd subunit Dabb PF07876.12 CBZ28170.1 - 4.6e-10 40.0 0.0 6.3e-10 39.6 0.0 1.2 1 0 0 1 1 1 1 Stress responsive A/B Barrel Domain Dabb PF07876.12 CBZ28171.1 - 4.8e-08 33.5 0.0 6.2e-08 33.2 0.0 1.2 1 0 0 1 1 1 1 Stress responsive A/B Barrel Domain Ras PF00071.22 CBZ28172.1 - 6.1e-64 214.5 0.6 7e-64 214.3 0.6 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CBZ28172.1 - 4.5e-37 126.9 0.6 6e-37 126.5 0.1 1.4 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CBZ28172.1 - 5.4e-16 58.5 0.1 6.6e-16 58.3 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 CBZ28172.1 - 6.1e-07 29.5 0.8 0.0069 16.3 0.2 2.2 1 1 1 2 2 2 2 RsgA GTPase Gtr1_RagA PF04670.12 CBZ28172.1 - 1.4e-06 27.8 0.1 1.7e-06 27.5 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 CBZ28172.1 - 3.7e-05 23.2 0.2 5.7e-05 22.6 0.2 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.27 CBZ28172.1 - 4.9e-05 23.0 0.4 0.00011 21.8 0.2 1.7 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 CBZ28172.1 - 7.2e-05 22.8 0.1 0.00026 21.0 0.0 1.7 1 1 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 CBZ28172.1 - 0.00082 18.9 0.1 0.0043 16.6 0.1 1.9 1 1 0 1 1 1 1 Ferrous iron transport protein B AAA PF00004.29 CBZ28172.1 - 0.0074 16.7 0.1 0.71 10.3 0.0 2.3 1 1 1 2 2 2 1 ATPase family associated with various cellular activities (AAA) G-alpha PF00503.20 CBZ28172.1 - 0.01 15.0 4.1 0.034 13.3 0.8 2.5 1 1 1 2 2 2 0 G-protein alpha subunit AAA_16 PF13191.6 CBZ28172.1 - 0.017 15.5 0.0 0.027 14.9 0.0 1.4 1 1 0 1 1 1 0 AAA ATPase domain ABC_tran PF00005.27 CBZ28172.1 - 0.021 15.4 0.2 0.13 12.8 0.2 1.9 1 1 0 1 1 1 0 ABC transporter AAA_22 PF13401.6 CBZ28172.1 - 0.053 13.8 0.0 0.14 12.5 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA_29 PF13555.6 CBZ28172.1 - 0.067 12.9 0.0 0.14 11.9 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_7 PF12775.7 CBZ28172.1 - 0.1 12.1 0.0 0.23 11.0 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region TniB PF05621.11 CBZ28172.1 - 0.12 11.8 0.0 0.24 10.8 0.0 1.5 1 0 0 1 1 1 0 Bacterial TniB protein MCU PF04678.13 CBZ28174.1 - 2.1e-43 148.5 0.1 3.7e-43 147.7 0.1 1.4 1 0 0 1 1 1 1 Mitochondrial calcium uniporter LCE PF14672.6 CBZ28174.1 - 0.095 13.3 0.5 0.21 12.2 0.5 1.6 1 0 0 1 1 1 0 Late cornified envelope Glyoxalase_4 PF13669.6 CBZ28174.1 - 0.14 12.5 0.0 0.25 11.6 0.0 1.5 1 0 0 1 1 1 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily MatE PF01554.18 CBZ28175.1 - 3e-35 121.2 23.0 3.5e-18 65.8 7.8 2.5 2 0 0 2 2 2 2 MatE Polysacc_synt_C PF14667.6 CBZ28175.1 - 0.0035 17.4 4.8 0.0035 17.4 4.8 3.5 3 0 0 3 3 3 2 Polysaccharide biosynthesis C-terminal domain FAM176 PF14851.6 CBZ28175.1 - 0.021 14.5 0.2 0.049 13.3 0.2 1.6 1 0 0 1 1 1 0 FAM176 family LRR_6 PF13516.6 CBZ28176.1 - 2.3e-06 27.2 8.6 0.0055 16.7 0.2 4.4 4 0 0 4 4 4 3 Leucine Rich repeat LRR_8 PF13855.6 CBZ28176.1 - 0.12 12.2 1.6 1.9 8.3 1.4 2.8 2 1 0 2 2 2 0 Leucine rich repeat Glutaredoxin PF00462.24 CBZ28177.1 - 6.7e-16 58.3 0.1 9.5e-16 57.8 0.1 1.2 1 0 0 1 1 1 1 Glutaredoxin Thioredoxin_3 PF13192.6 CBZ28177.1 - 6.4e-05 22.9 0.1 8.5e-05 22.5 0.1 1.2 1 0 0 1 1 1 1 Thioredoxin domain GST_N_3 PF13417.6 CBZ28177.1 - 0.0001 22.6 0.0 0.00012 22.4 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Thioredoxin_2 PF13098.6 CBZ28177.1 - 0.00035 21.0 0.3 0.00042 20.7 0.3 1.4 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_4 PF13462.6 CBZ28177.1 - 0.00089 19.4 0.1 0.7 10.0 0.2 2.1 1 1 1 2 2 2 2 Thioredoxin DUF836 PF05768.14 CBZ28177.1 - 0.0019 18.6 0.1 0.0022 18.4 0.1 1.2 1 0 0 1 1 1 1 Glutaredoxin-like domain (DUF836) DSBA PF01323.20 CBZ28177.1 - 0.0035 17.1 0.3 0.19 11.5 0.3 2.1 1 1 1 2 2 2 1 DSBA-like thioredoxin domain Redoxin PF08534.10 CBZ28177.1 - 0.055 13.2 0.1 0.083 12.6 0.1 1.3 1 0 0 1 1 1 0 Redoxin GST_N_2 PF13409.6 CBZ28177.1 - 0.069 13.5 0.0 0.11 12.8 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain zf-RING_7 PF02591.15 CBZ28177.1 - 0.083 13.1 0.1 0.71 10.1 0.0 2.4 3 0 0 3 3 3 0 C4-type zinc ribbon domain TRAF6_Z2 PF18048.1 CBZ28177.1 - 0.14 12.3 0.1 1 9.5 0.0 2.2 2 0 0 2 2 2 0 TNF receptor-associated factor 6 zinc finger 2 DUF929 PF06053.11 CBZ28177.1 - 0.35 10.2 1.2 0.79 9.0 0.4 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF929) Beta_helix PF13229.6 CBZ28178.1 - 2e-97 323.4 103.9 7.4e-16 58.4 1.2 17.2 9 5 7 16 16 16 14 Right handed beta helix region NosD PF05048.13 CBZ28178.1 - 1e-73 247.6 48.9 1.2e-11 44.4 3.4 15.5 10 5 6 16 16 16 11 Periplasmic copper-binding protein (NosD) zf-RING_6 PF14835.6 CBZ28178.1 - 0.04 13.8 3.9 11 6.0 0.0 4.2 4 0 0 4 4 4 0 zf-RING of BARD1-type protein FliJ PF02050.16 CBZ28178.1 - 0.046 14.0 0.2 0.11 12.8 0.2 1.6 1 0 0 1 1 1 0 Flagellar FliJ protein DUF1565 PF07602.11 CBZ28178.1 - 1.7 7.9 53.1 0.37 10.1 0.0 12.0 9 3 3 14 14 14 0 Protein of unknown function (DUF1565) Hol_Tox PF16935.5 CBZ28180.1 - 0.053 13.6 0.0 0.13 12.3 0.0 1.7 1 0 0 1 1 1 0 Putative Holin-like Toxin (Hol-Tox) DUF2020 PF09449.10 CBZ28181.1 - 0.051 13.4 0.3 0.11 12.3 0.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF2020) WD40 PF00400.32 CBZ28182.1 - 2.9e-05 24.7 10.1 0.0099 16.7 0.1 5.3 6 0 0 6 6 6 2 WD domain, G-beta repeat DUF1126 PF06565.12 CBZ28183.1 - 3.7e-79 261.3 2.3 7.8e-26 89.9 0.2 3.3 3 0 0 3 3 3 3 DUF1126 PH-like domain EF-hand_7 PF13499.6 CBZ28183.1 - 1.9e-08 34.6 0.4 1e-05 25.9 0.0 3.0 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_8 PF13833.6 CBZ28183.1 - 7.8e-06 25.6 0.7 0.023 14.5 0.1 2.9 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 CBZ28183.1 - 0.0034 17.2 0.2 7.2 6.8 0.1 4.2 4 0 0 4 4 4 1 EF-hand domain DUF1456 PF07308.13 CBZ28183.1 - 0.082 13.3 0.2 4.1 7.8 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF1456) E1_dh PF00676.20 CBZ28185.1 - 5.8e-57 192.9 0.0 9.7e-57 192.2 0.0 1.2 1 0 0 1 1 1 1 Dehydrogenase E1 component Transket_pyr PF02779.24 CBZ28185.1 - 2e-47 161.2 0.0 3.4e-47 160.4 0.0 1.4 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain OxoGdeHyase_C PF16870.5 CBZ28185.1 - 5.7e-37 126.7 0.0 1e-36 125.9 0.0 1.4 1 0 0 1 1 1 1 2-oxoglutarate dehydrogenase C-terminal 2-oxogl_dehyd_N PF16078.5 CBZ28185.1 - 9.1e-05 22.0 0.1 0.00018 21.0 0.1 1.6 1 0 0 1 1 1 1 2-oxoglutarate dehydrogenase N-terminus Vta1 PF04652.16 CBZ28185.1 - 0.16 12.0 0.0 0.66 9.9 0.0 1.9 2 0 0 2 2 2 0 Vta1 like PIP5K PF01504.18 CBZ28186.1 - 2.7e-33 115.4 0.0 7.6e-16 58.2 0.0 3.2 2 1 1 3 3 3 3 Phosphatidylinositol-4-phosphate 5-Kinase FYVE PF01363.21 CBZ28186.1 - 7.4e-17 61.3 5.1 1.5e-16 60.3 5.1 1.5 1 0 0 1 1 1 1 FYVE zinc finger IBR PF01485.21 CBZ28186.1 - 0.65 10.3 3.8 1.8 8.8 3.8 1.7 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain NOB1_Zn_bind PF08772.11 CBZ28186.1 - 1 9.5 5.7 3.2 8.0 5.7 1.8 1 0 0 1 1 1 0 Nin one binding (NOB1) Zn-ribbon like Zn-ribbon_8 PF09723.10 CBZ28186.1 - 2.8 8.1 5.3 12 6.1 5.3 2.1 1 0 0 1 1 1 0 Zinc ribbon domain DUF778 PF05608.12 CBZ28187.1 - 3.7e-33 115.5 3.6 4.5e-19 69.6 0.1 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF778) Pep3_Vps18 PF05131.14 CBZ28188.1 - 9.2e-09 35.3 0.0 1.3e-07 31.5 0.0 2.6 2 1 0 2 2 2 1 Pep3/Vps18/deep orange family Clathrin PF00637.20 CBZ28188.1 - 5.1e-07 29.7 0.1 1.4e-06 28.2 0.0 1.7 2 0 0 2 2 2 1 Region in Clathrin and VPS Vps39_2 PF10367.9 CBZ28188.1 - 1.4e-06 28.7 0.2 3.3e-06 27.5 0.2 1.7 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 Clathrin_H_link PF13838.6 CBZ28188.1 - 0.0056 16.6 0.0 0.034 14.1 0.0 2.2 2 0 0 2 2 2 1 Clathrin-H-link Zn_ribbon_17 PF17120.5 CBZ28188.1 - 0.021 14.4 0.5 0.021 14.4 0.5 2.2 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type zf-RING_2 PF13639.6 CBZ28188.1 - 0.045 14.1 0.7 0.045 14.1 0.7 3.1 4 0 0 4 4 4 0 Ring finger domain zf-RING_UBOX PF13445.6 CBZ28188.1 - 0.14 12.2 0.9 0.38 10.8 0.9 1.7 1 0 0 1 1 1 0 RING-type zinc-finger Occludin_ELL PF07303.13 CBZ28188.1 - 0.18 12.5 1.2 0.33 11.7 0.3 1.9 2 0 0 2 2 2 0 Occludin homology domain zf-RING_5 PF14634.6 CBZ28188.1 - 2.9 7.9 9.0 0.11 12.5 2.5 2.1 2 1 0 2 2 2 0 zinc-RING finger domain Prok-RING_4 PF14447.6 CBZ28188.1 - 7.6 6.5 6.6 1.9 8.4 0.1 2.8 3 0 0 3 3 3 0 Prokaryotic RING finger family 4 Prok-RING_1 PF14446.6 CBZ28188.1 - 9.2 6.3 6.8 3.2 7.8 0.6 2.7 3 0 0 3 3 3 0 Prokaryotic RING finger family 1 DUF1295 PF06966.12 CBZ28189.1 - 2.2e-27 96.1 15.6 4.6e-27 95.1 15.6 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF1295) DUF423 PF04241.15 CBZ28189.1 - 3 8.1 6.5 0.91 9.8 1.1 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF423) Acyl-CoA_dh_1 PF00441.24 CBZ28190.1 - 3.6e-39 134.4 0.7 3.6e-39 134.4 0.7 1.6 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 CBZ28190.1 - 9.2e-29 100.4 0.0 2.3e-28 99.1 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 CBZ28190.1 - 1.8e-23 82.6 0.1 3.6e-23 81.6 0.1 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 CBZ28190.1 - 3.5e-19 69.4 1.0 4.6e-19 69.0 0.1 1.6 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_ox_N PF14749.6 CBZ28190.1 - 0.14 12.7 0.0 0.24 11.9 0.0 1.4 1 0 0 1 1 1 0 Acyl-coenzyme A oxidase N-terminal Sec8_exocyst PF04048.14 CBZ28190.1 - 0.2 11.5 0.1 0.38 10.6 0.1 1.4 1 0 0 1 1 1 0 Sec8 exocyst complex component specific domain XRN_N PF03159.18 CBZ28191.1 - 8.5e-27 94.1 0.0 1.3e-26 93.5 0.0 1.2 1 0 0 1 1 1 1 XRN 5'-3' exonuclease N-terminus XPG_N PF00752.17 CBZ28191.1 - 0.018 15.5 0.0 0.043 14.3 0.0 1.6 1 0 0 1 1 1 0 XPG N-terminal domain ABC2_membrane_3 PF12698.7 CBZ28194.1 - 1.1e-67 228.6 50.6 2.3e-44 151.9 17.0 3.0 2 1 0 2 2 2 2 ABC-2 family transporter protein ABC_tran PF00005.27 CBZ28194.1 - 8.7e-53 178.5 0.0 9.9e-28 97.4 0.0 2.4 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 CBZ28194.1 - 1e-15 58.4 0.1 6e-06 26.3 0.0 4.2 3 1 1 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 CBZ28194.1 - 9.2e-05 23.0 2.1 0.43 11.0 0.0 2.7 3 0 0 3 3 3 2 AAA domain SMC_N PF02463.19 CBZ28194.1 - 0.00019 20.9 0.0 2.2 7.7 0.0 3.5 2 2 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 CBZ28194.1 - 0.00042 20.0 0.2 0.13 12.0 0.1 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_30 PF13604.6 CBZ28194.1 - 0.00044 20.0 0.0 0.047 13.4 0.0 2.5 2 0 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 CBZ28194.1 - 0.00066 19.6 0.0 0.02 14.8 0.0 2.4 2 0 0 2 2 2 1 RsgA GTPase DUF4162 PF13732.6 CBZ28194.1 - 0.00078 20.1 0.0 0.37 11.5 0.0 2.6 2 0 0 2 2 2 1 Domain of unknown function (DUF4162) SbcCD_C PF13558.6 CBZ28194.1 - 0.0014 18.8 0.0 1.1 9.5 0.0 3.7 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit Zeta_toxin PF06414.12 CBZ28194.1 - 0.0018 17.6 0.1 2.9 7.1 0.0 3.2 3 0 0 3 3 3 1 Zeta toxin AAA_15 PF13175.6 CBZ28194.1 - 0.0051 16.6 0.0 3.7 7.1 0.0 3.3 3 0 0 3 3 3 1 AAA ATPase domain SRP54 PF00448.22 CBZ28194.1 - 0.017 14.8 0.3 4.4 6.9 0.0 2.6 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain MMR_HSR1 PF01926.23 CBZ28194.1 - 0.14 12.3 0.2 6.8 6.8 0.0 2.7 2 0 0 2 2 2 0 50S ribosome-binding GTPase RNA_helicase PF00910.22 CBZ28194.1 - 0.15 12.5 0.1 22 5.5 0.0 2.8 2 0 0 2 2 2 0 RNA helicase APS_kinase PF01583.20 CBZ28194.1 - 0.15 11.9 0.2 0.51 10.2 0.1 1.9 2 0 0 2 2 2 0 Adenylylsulphate kinase AAA_28 PF13521.6 CBZ28194.1 - 0.25 11.5 2.1 10 6.3 0.1 3.7 4 0 0 4 4 4 0 AAA domain ABC2_membrane PF01061.24 CBZ28194.1 - 0.61 9.5 51.9 0.042 13.3 17.2 4.2 4 1 0 4 4 4 0 ABC-2 type transporter ABC2_membrane_3 PF12698.7 CBZ28195.1 - 1.4e-45 156.0 16.3 1.9e-45 155.5 16.3 1.2 1 0 0 1 1 1 1 ABC-2 family transporter protein ABC_tran PF00005.27 CBZ28195.1 - 8.9e-23 81.3 0.0 1.7e-22 80.4 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 CBZ28195.1 - 4.6e-09 36.5 0.0 2.4e-06 27.6 0.0 2.3 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system DUF4162 PF13732.6 CBZ28195.1 - 0.00023 21.8 0.0 0.14 12.9 0.0 2.8 3 0 0 3 3 3 1 Domain of unknown function (DUF4162) Zeta_toxin PF06414.12 CBZ28195.1 - 0.02 14.2 0.0 1.1 8.5 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin Herpes_LMP1 PF05297.11 CBZ28195.1 - 0.023 13.9 4.9 0.043 13.0 4.9 1.3 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) PDR_CDR PF06422.12 CBZ28195.1 - 0.17 11.8 0.3 0.77 9.7 0.3 2.1 1 0 0 1 1 1 0 CDR ABC transporter AAA_23 PF13476.6 CBZ28195.1 - 0.17 12.3 2.0 0.28 11.7 0.1 1.9 2 0 0 2 2 2 0 AAA domain DUF4407 PF14362.6 CBZ28195.1 - 1.5 8.1 6.0 2.5 7.4 3.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) TatD_DNase PF01026.21 CBZ28197.1 - 4.8e-39 134.3 0.0 5.8e-39 134.0 0.0 1.1 1 0 0 1 1 1 1 TatD related DNase Amidohydro_2 PF04909.14 CBZ28197.1 - 9.3e-05 22.3 0.4 0.21 11.3 0.0 2.5 1 1 1 2 2 2 2 Amidohydrolase Sec6 PF06046.13 CBZ28198.1 - 1.4e-12 46.8 1.3 1.5e-09 36.8 2.6 2.4 2 0 0 2 2 2 2 Exocyst complex component Sec6 Pyridox_ox_2 PF12900.7 CBZ28199.1 - 0.0087 16.1 0.2 0.21 11.6 0.1 2.2 2 0 0 2 2 2 1 Pyridoxamine 5'-phosphate oxidase DUF896 PF05979.12 CBZ28199.1 - 0.038 13.9 0.3 0.24 11.3 0.1 2.1 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF896) AAA PF00004.29 CBZ28203.1 - 4.9e-87 289.1 0.0 3.1e-47 160.3 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 CBZ28203.1 - 4.3e-24 84.1 0.4 7e-11 41.8 0.0 3.1 3 0 0 3 3 2 2 AAA+ lid domain RuvB_N PF05496.12 CBZ28203.1 - 1.1e-16 61.0 0.0 8.9e-09 35.3 0.0 2.5 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 CBZ28203.1 - 6.7e-13 49.4 0.8 0.00034 21.1 0.3 4.2 2 2 1 3 3 3 2 AAA ATPase domain AAA_5 PF07728.14 CBZ28203.1 - 3.8e-11 43.1 0.2 0.00033 20.7 0.0 3.9 3 2 0 3 3 3 2 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 CBZ28203.1 - 4.9e-11 43.0 0.0 2.4e-05 24.5 0.0 2.9 2 1 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_33 PF13671.6 CBZ28203.1 - 5.1e-09 36.4 0.0 0.0018 18.5 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.6 CBZ28203.1 - 6.7e-09 36.1 1.2 0.013 15.8 0.0 4.4 3 2 0 3 3 2 2 AAA domain AAA_14 PF13173.6 CBZ28203.1 - 1.5e-07 31.5 0.0 0.015 15.3 0.0 2.5 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.22 CBZ28203.1 - 8.9e-07 29.3 0.0 0.034 14.5 0.0 3.1 3 0 0 3 3 3 2 RNA helicase AAA_18 PF13238.6 CBZ28203.1 - 2.5e-06 28.1 0.0 0.065 13.8 0.0 2.8 2 1 0 2 2 2 2 AAA domain IstB_IS21 PF01695.17 CBZ28203.1 - 3.4e-06 26.9 0.0 0.11 12.3 0.0 2.4 2 0 0 2 2 2 2 IstB-like ATP binding protein TsaE PF02367.17 CBZ28203.1 - 1.3e-05 25.2 0.0 0.21 11.6 0.0 2.3 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE TIP49 PF06068.13 CBZ28203.1 - 1.5e-05 24.4 0.0 0.14 11.4 0.0 2.3 2 0 0 2 2 2 2 TIP49 P-loop domain Zeta_toxin PF06414.12 CBZ28203.1 - 2.4e-05 23.7 0.0 0.021 14.1 0.0 2.7 2 0 0 2 2 2 1 Zeta toxin AAA_3 PF07726.11 CBZ28203.1 - 3.7e-05 23.6 0.0 0.38 10.6 0.0 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.21 CBZ28203.1 - 4e-05 23.1 0.2 0.049 13.0 0.0 2.5 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI NACHT PF05729.12 CBZ28203.1 - 8e-05 22.6 0.2 0.34 10.8 0.0 3.0 3 0 0 3 3 3 2 NACHT domain AAA_28 PF13521.6 CBZ28203.1 - 9.1e-05 22.8 0.0 0.37 11.0 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_24 PF13479.6 CBZ28203.1 - 9.8e-05 22.2 0.0 0.49 10.1 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_11 PF13086.6 CBZ28203.1 - 0.00021 21.2 0.0 0.34 10.6 0.0 2.3 2 0 0 2 2 2 2 AAA domain ABC_tran PF00005.27 CBZ28203.1 - 0.00021 21.8 0.6 0.39 11.2 0.0 2.9 3 1 0 3 3 2 1 ABC transporter Sigma54_activat PF00158.26 CBZ28203.1 - 0.00042 20.1 0.0 0.09 12.5 0.0 2.9 3 0 0 3 3 2 1 Sigma-54 interaction domain AAA_17 PF13207.6 CBZ28203.1 - 0.00071 20.0 0.0 0.33 11.4 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_7 PF12775.7 CBZ28203.1 - 0.00098 18.7 0.1 0.63 9.5 0.0 2.6 2 1 0 2 2 2 1 P-loop containing dynein motor region NB-ARC PF00931.22 CBZ28203.1 - 0.0013 18.0 0.1 0.79 8.8 0.0 2.5 3 0 0 3 3 2 1 NB-ARC domain NTPase_1 PF03266.15 CBZ28203.1 - 0.0014 18.5 0.5 0.19 11.7 0.0 2.8 3 0 0 3 3 2 1 NTPase Rad17 PF03215.15 CBZ28203.1 - 0.0015 18.5 0.0 0.075 12.9 0.0 2.5 2 0 0 2 2 2 1 Rad17 P-loop domain Vps4_C PF09336.10 CBZ28203.1 - 0.0015 18.5 0.0 0.012 15.6 0.0 2.5 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain ATPase_2 PF01637.18 CBZ28203.1 - 0.0019 18.2 0.0 0.33 10.8 0.0 2.6 2 0 0 2 2 2 1 ATPase domain predominantly from Archaea Viral_helicase1 PF01443.18 CBZ28203.1 - 0.0021 17.8 0.0 0.51 10.0 0.0 2.3 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase Bac_DnaA PF00308.18 CBZ28203.1 - 0.0042 16.9 0.0 1.5 8.6 0.0 2.5 2 0 0 2 2 2 1 Bacterial dnaA protein AAA_19 PF13245.6 CBZ28203.1 - 0.0042 17.4 0.0 4.1 7.7 0.0 2.6 2 0 0 2 2 2 1 AAA domain Sigma54_activ_2 PF14532.6 CBZ28203.1 - 0.0052 16.9 0.0 0.047 13.8 0.0 2.5 3 0 0 3 3 2 1 Sigma-54 interaction domain Parvo_NS1 PF01057.17 CBZ28203.1 - 0.0059 15.7 0.1 0.44 9.6 0.0 2.2 2 0 0 2 2 2 1 Parvovirus non-structural protein NS1 AAA_25 PF13481.6 CBZ28203.1 - 0.0065 16.1 4.0 2.9 7.4 0.1 3.7 2 2 1 4 4 4 1 AAA domain DUF815 PF05673.13 CBZ28203.1 - 0.019 14.1 0.0 3.3 6.8 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF815) MCM PF00493.23 CBZ28203.1 - 0.024 13.7 0.0 2.4 7.2 0.0 2.3 2 0 0 2 2 2 0 MCM P-loop domain AAA_30 PF13604.6 CBZ28203.1 - 0.025 14.3 0.1 9 6.0 0.0 2.8 3 0 0 3 3 3 0 AAA domain TniB PF05621.11 CBZ28203.1 - 0.045 13.2 0.0 18 4.7 0.0 3.2 3 0 0 3 3 3 0 Bacterial TniB protein ATPase PF06745.13 CBZ28203.1 - 0.13 11.6 0.2 3 7.1 0.0 2.6 2 1 0 2 2 2 0 KaiC SKI PF01202.22 CBZ28203.1 - 0.15 12.2 0.0 1.4 9.0 0.0 2.4 2 0 0 2 2 2 0 Shikimate kinase AAA_29 PF13555.6 CBZ28203.1 - 0.16 11.7 0.0 7.5 6.4 0.0 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain Aminotran_5 PF00266.19 CBZ28204.1 - 7e-82 275.3 0.0 8.4e-82 275.1 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 CBZ28204.1 - 3.7e-10 39.5 0.0 5.4e-10 39.0 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.17 CBZ28204.1 - 0.00098 18.5 0.1 0.0015 17.9 0.1 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Pyridoxal_deC PF00282.19 CBZ28204.1 - 0.0031 16.3 0.0 0.0052 15.6 0.0 1.3 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain AAA PF00004.29 CBZ28205.1 - 1.4e-36 125.8 0.0 7.6e-27 94.3 0.0 3.5 2 1 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 CBZ28205.1 - 8.6e-14 52.0 0.6 1.6e-06 28.4 0.0 3.3 2 1 0 2 2 2 2 AAA domain AAA_16 PF13191.6 CBZ28205.1 - 4.7e-11 43.4 0.8 0.00018 22.0 0.0 3.3 2 2 0 2 2 2 2 AAA ATPase domain AAA_18 PF13238.6 CBZ28205.1 - 2.2e-09 38.0 0.0 0.0027 18.3 0.0 3.2 3 0 0 3 3 2 2 AAA domain IstB_IS21 PF01695.17 CBZ28205.1 - 1.6e-08 34.5 0.0 3.5e-05 23.6 0.0 2.8 3 0 0 3 3 3 2 IstB-like ATP binding protein Mg_chelatase PF01078.21 CBZ28205.1 - 3.9e-07 29.7 0.0 0.00064 19.2 0.0 2.4 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 CBZ28205.1 - 4.7e-07 29.9 0.0 0.0081 16.2 0.0 2.8 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) TIP49 PF06068.13 CBZ28205.1 - 1.6e-06 27.6 0.0 0.047 12.9 0.0 2.2 2 0 0 2 2 2 2 TIP49 P-loop domain AAA_33 PF13671.6 CBZ28205.1 - 1.8e-06 28.2 0.0 0.073 13.2 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_30 PF13604.6 CBZ28205.1 - 3.3e-06 27.0 0.2 0.00078 19.2 0.2 2.7 2 0 0 2 2 2 1 AAA domain AAA_2 PF07724.14 CBZ28205.1 - 4.6e-06 26.8 0.0 0.0004 20.6 0.0 2.5 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_28 PF13521.6 CBZ28205.1 - 6.9e-06 26.4 0.0 0.0046 17.2 0.0 2.6 2 0 0 2 2 2 1 AAA domain Sigma54_activat PF00158.26 CBZ28205.1 - 3.7e-05 23.5 0.0 0.14 11.8 0.0 2.4 2 0 0 2 2 2 2 Sigma-54 interaction domain ABC_tran PF00005.27 CBZ28205.1 - 4e-05 24.2 0.3 0.26 11.8 0.1 2.9 2 1 1 3 3 2 2 ABC transporter AAA_24 PF13479.6 CBZ28205.1 - 4.1e-05 23.4 0.0 0.3 10.8 0.0 2.8 2 1 0 2 2 2 2 AAA domain AAA_19 PF13245.6 CBZ28205.1 - 5e-05 23.7 0.0 0.42 10.9 0.0 2.7 2 0 0 2 2 2 2 AAA domain Sigma54_activ_2 PF14532.6 CBZ28205.1 - 0.0001 22.4 0.0 0.1 12.7 0.0 2.9 3 0 0 3 3 3 1 Sigma-54 interaction domain DUF2075 PF09848.9 CBZ28205.1 - 0.00012 21.5 0.1 0.093 11.9 0.0 2.2 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) AAA_17 PF13207.6 CBZ28205.1 - 0.00012 22.5 0.0 0.67 10.4 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.6 CBZ28205.1 - 0.00028 20.5 0.0 0.065 13.0 0.0 2.9 3 0 0 3 3 2 1 P-loop containing region of AAA domain RNA_helicase PF00910.22 CBZ28205.1 - 0.00034 21.0 0.0 0.74 10.2 0.0 2.5 2 0 0 2 2 2 2 RNA helicase AAA_lid_3 PF17862.1 CBZ28205.1 - 0.00064 19.5 0.1 0.0015 18.3 0.1 1.6 1 0 0 1 1 1 1 AAA+ lid domain NB-ARC PF00931.22 CBZ28205.1 - 0.00084 18.6 0.0 0.18 11.0 0.0 2.5 2 0 0 2 2 2 1 NB-ARC domain AAA_25 PF13481.6 CBZ28205.1 - 0.00099 18.7 1.1 1.3 8.5 0.0 4.3 5 0 0 5 5 5 1 AAA domain AAA_7 PF12775.7 CBZ28205.1 - 0.001 18.6 0.1 0.75 9.3 0.0 2.3 2 0 0 2 2 2 1 P-loop containing dynein motor region NACHT PF05729.12 CBZ28205.1 - 0.0015 18.4 0.1 3.7 7.4 0.0 3.3 3 1 0 3 3 3 1 NACHT domain TsaE PF02367.17 CBZ28205.1 - 0.0017 18.3 0.0 1.3 9.0 0.0 2.4 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE RuvB_N PF05496.12 CBZ28205.1 - 0.002 17.9 0.1 0.91 9.3 0.0 2.4 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_11 PF13086.6 CBZ28205.1 - 0.0032 17.3 0.0 1 9.1 0.0 2.5 2 0 0 2 2 2 1 AAA domain TniB PF05621.11 CBZ28205.1 - 0.0042 16.5 0.2 0.38 10.1 0.0 3.2 3 1 0 3 3 2 1 Bacterial TniB protein Rad17 PF03215.15 CBZ28205.1 - 0.0047 16.9 0.0 0.8 9.6 0.0 2.4 2 0 0 2 2 2 1 Rad17 P-loop domain KTI12 PF08433.10 CBZ28205.1 - 0.0063 16.0 0.0 0.77 9.2 0.0 2.3 2 0 0 2 2 2 1 Chromatin associated protein KTI12 MeaB PF03308.16 CBZ28205.1 - 0.013 14.5 0.8 0.056 12.4 0.2 2.4 3 0 0 3 3 3 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Viral_helicase1 PF01443.18 CBZ28205.1 - 0.014 15.2 0.0 0.085 12.6 0.0 2.2 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase NTPase_1 PF03266.15 CBZ28205.1 - 0.015 15.2 0.1 1.1 9.1 0.0 2.6 2 0 0 2 2 2 0 NTPase AAA_14 PF13173.6 CBZ28205.1 - 0.016 15.2 0.0 2.5 8.1 0.0 2.7 2 0 0 2 2 2 0 AAA domain 6PF2K PF01591.18 CBZ28205.1 - 0.037 13.3 0.0 4.5 6.5 0.0 2.3 2 0 0 2 2 2 0 6-phosphofructo-2-kinase MMR_HSR1 PF01926.23 CBZ28205.1 - 0.058 13.5 0.0 0.61 10.2 0.0 2.5 2 0 0 2 2 2 0 50S ribosome-binding GTPase Parvo_NS1 PF01057.17 CBZ28205.1 - 0.065 12.3 0.0 3.5 6.7 0.0 2.3 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 Ploopntkinase3 PF18751.1 CBZ28205.1 - 0.067 13.1 0.0 0.3 11.0 0.0 2.1 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 TrwB_AAD_bind PF10412.9 CBZ28205.1 - 0.076 11.9 0.1 4 6.2 0.1 3.0 3 0 0 3 3 3 0 Type IV secretion-system coupling protein DNA-binding domain AAA_23 PF13476.6 CBZ28205.1 - 0.085 13.3 0.0 1.8 9.0 0.1 2.3 2 0 0 2 2 2 0 AAA domain PRK PF00485.18 CBZ28205.1 - 0.097 12.4 0.0 0.26 11.0 0.0 1.7 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family TPR_14 PF13428.6 CBZ28206.1 - 3.2e-11 43.0 43.5 0.025 15.4 0.1 16.1 13 4 4 17 17 17 2 Tetratricopeptide repeat TPR_19 PF14559.6 CBZ28206.1 - 2.2e-08 34.5 19.5 0.079 13.5 0.0 10.2 11 0 0 11 11 11 2 Tetratricopeptide repeat TPR_11 PF13414.6 CBZ28206.1 - 3e-06 26.8 2.3 1.3 8.8 0.0 5.7 6 0 0 6 6 6 2 TPR repeat TPR_1 PF00515.28 CBZ28206.1 - 6e-06 25.9 8.0 2.6 8.0 0.0 7.5 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_12 PF13424.6 CBZ28206.1 - 3.9e-05 23.9 43.2 0.0093 16.2 2.6 10.7 10 1 0 10 10 10 2 Tetratricopeptide repeat TPR_7 PF13176.6 CBZ28206.1 - 5e-05 23.0 16.1 2.7 8.2 0.0 8.8 9 0 0 9 9 9 2 Tetratricopeptide repeat TPR_2 PF07719.17 CBZ28206.1 - 0.00021 21.1 24.9 7.5 6.9 0.1 11.7 13 0 0 13 13 13 1 Tetratricopeptide repeat TPR_17 PF13431.6 CBZ28206.1 - 0.00078 19.7 16.6 2.7 8.6 0.1 8.2 9 0 0 9 9 9 2 Tetratricopeptide repeat TPR_8 PF13181.6 CBZ28206.1 - 0.017 15.3 16.2 18 5.9 0.0 9.1 11 0 0 11 11 11 0 Tetratricopeptide repeat TPR_16 PF13432.6 CBZ28206.1 - 0.068 13.8 0.0 0.068 13.8 0.0 11.2 13 1 1 14 14 14 0 Tetratricopeptide repeat EBP PF05241.12 CBZ28207.1 - 8.9e-14 51.3 5.3 1.1e-13 51.0 5.3 1.1 1 0 0 1 1 1 1 Emopamil binding protein DUF2781 PF10914.8 CBZ28207.1 - 9e-05 22.9 8.2 0.00011 22.6 8.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2781) YtpI PF14007.6 CBZ28207.1 - 0.038 14.1 0.2 0.08 13.1 0.2 1.6 1 0 0 1 1 1 0 YtpI-like protein MRP PF09387.10 CBZ28209.1 - 9.1e-50 169.4 0.3 9.1e-50 169.4 0.3 2.0 2 0 0 2 2 2 1 Mitochondrial RNA binding protein MRP WGG PF10273.9 CBZ28210.1 - 5.9e-05 23.6 0.6 0.00017 22.1 0.6 1.8 1 1 0 1 1 1 1 Pre-rRNA-processing protein TSR2 DUF5435 PF17503.2 CBZ28210.1 - 0.0017 18.2 0.0 0.0024 17.6 0.0 1.2 1 0 0 1 1 1 1 Family of unknown function (DUF5435) Glyco_transf_43 PF03360.16 CBZ28210.1 - 0.0017 18.2 0.0 0.0019 18.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 43 Virul_Fac PF10139.9 CBZ28210.1 - 0.0033 15.8 1.0 0.0042 15.4 1.0 1.0 1 0 0 1 1 1 1 Putative bacterial virulence factor TPR_16 PF13432.6 CBZ28212.1 - 2.2e-24 85.8 23.5 2.7e-05 24.7 0.0 7.3 6 1 3 9 9 8 6 Tetratricopeptide repeat TPR_1 PF00515.28 CBZ28212.1 - 3e-24 83.8 48.1 9.2e-05 22.1 1.0 11.7 12 0 0 12 12 12 7 Tetratricopeptide repeat TPR_2 PF07719.17 CBZ28212.1 - 4.6e-23 79.4 48.1 0.0012 18.8 0.5 12.0 12 0 0 12 12 12 6 Tetratricopeptide repeat TPR_19 PF14559.6 CBZ28212.1 - 7.6e-18 64.8 25.7 2.3e-05 24.8 1.2 7.6 6 2 3 9 9 9 6 Tetratricopeptide repeat TPR_12 PF13424.6 CBZ28212.1 - 9.5e-18 64.3 33.7 9.1e-06 25.9 0.2 9.3 8 4 1 9 9 9 6 Tetratricopeptide repeat TPR_6 PF13174.6 CBZ28212.1 - 2.9e-17 62.0 28.3 0.00014 22.3 0.1 10.9 12 0 0 12 12 12 4 Tetratricopeptide repeat TPR_8 PF13181.6 CBZ28212.1 - 4.3e-17 60.8 33.9 0.0062 16.7 0.5 10.5 12 0 0 12 12 9 5 Tetratricopeptide repeat TPR_7 PF13176.6 CBZ28212.1 - 4.3e-16 57.7 27.4 0.041 13.9 0.0 10.3 11 0 0 11 11 11 4 Tetratricopeptide repeat TPR_14 PF13428.6 CBZ28212.1 - 4.2e-13 48.9 12.5 0.037 14.8 0.0 9.2 5 3 4 9 9 8 3 Tetratricopeptide repeat TPR_11 PF13414.6 CBZ28212.1 - 1.4e-09 37.5 28.9 2.2e-06 27.2 1.3 8.3 9 1 0 9 9 9 3 TPR repeat ANAPC3 PF12895.7 CBZ28212.1 - 1.1e-08 35.2 32.2 0.00074 19.7 0.9 7.3 5 2 2 7 7 7 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.6 CBZ28212.1 - 1.3e-06 28.4 4.5 0.13 12.4 0.0 5.7 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_17 PF13431.6 CBZ28212.1 - 2.3e-05 24.5 29.3 0.01 16.1 0.5 10.0 11 0 0 11 11 11 1 Tetratricopeptide repeat DUF3808 PF10300.9 CBZ28212.1 - 7e-05 21.8 1.9 0.0045 15.8 0.1 2.7 2 1 0 2 2 2 1 Protein of unknown function (DUF3808) Rapsyn_N PF10579.9 CBZ28212.1 - 0.0037 17.3 0.3 2 8.5 0.0 2.9 2 0 0 2 2 2 1 Rapsyn N-terminal myristoylation and linker region TPR_4 PF07721.14 CBZ28212.1 - 0.0068 16.9 0.7 37 5.4 0.0 4.9 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_10 PF13374.6 CBZ28212.1 - 0.02 14.8 31.8 4 7.4 0.0 9.2 11 0 0 11 11 10 0 Tetratricopeptide repeat HrpB1_HrpK PF09613.10 CBZ28212.1 - 0.071 12.8 0.3 35 4.1 0.0 3.7 4 0 0 4 4 4 0 Bacterial type III secretion protein (HrpB1_HrpK) DUF4919 PF16266.5 CBZ28212.1 - 0.11 12.4 6.6 1.2 9.0 0.1 2.9 3 0 0 3 3 2 0 Domain of unknown function (DUF4919) DUF3856 PF12968.7 CBZ28212.1 - 0.17 12.0 3.9 5 7.2 0.4 3.8 3 1 1 4 4 4 0 Domain of Unknown Function (DUF3856) Sec5 PF15469.6 CBZ28212.1 - 1.3 8.8 4.3 0.77 9.5 0.1 2.7 2 1 0 2 2 2 0 Exocyst complex component Sec5 PPR PF01535.20 CBZ28212.1 - 2.2 8.7 14.4 17 6.0 0.1 7.5 9 0 0 9 9 8 0 PPR repeat Sel1 PF08238.12 CBZ28212.1 - 2.7 8.8 19.8 3.1 8.6 0.1 6.9 7 1 1 8 8 5 0 Sel1 repeat JmjC PF02373.22 CBZ28214.1 - 7e-11 42.6 2.9 1.4e-09 38.4 2.9 2.3 1 1 0 1 1 1 1 JmjC domain, hydroxylase Cupin_8 PF13621.6 CBZ28214.1 - 0.00058 19.7 0.0 0.035 13.8 0.0 2.7 2 1 0 2 2 2 1 Cupin-like domain HTH_Tnp_ISL3 PF13542.6 CBZ28214.1 - 0.034 13.6 0.4 0.071 12.5 0.4 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 RAI16-like PF10257.9 CBZ28215.1 - 4.1e-07 29.2 0.0 0.0006 18.8 0.0 2.7 1 1 1 2 2 2 2 Retinoic acid induced 16-like protein Arm PF00514.23 CBZ28215.1 - 0.58 10.3 2.7 0.67 10.1 0.4 2.4 2 0 0 2 2 2 0 Armadillo/beta-catenin-like repeat CAP_N PF01213.19 CBZ28215.1 - 2.6 7.4 3.9 9.4 5.6 3.9 1.9 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal eIF-1a PF01176.19 CBZ28216.1 - 0.14 12.0 0.0 0.24 11.2 0.0 1.4 1 0 0 1 1 1 0 Translation initiation factor 1A / IF-1 SpoIIE PF07228.12 CBZ28217.1 - 0.0014 18.6 1.0 0.0097 15.8 0.6 2.5 2 1 0 2 2 2 1 Stage II sporulation protein E (SpoIIE) PP2C PF00481.21 CBZ28217.1 - 0.12 11.9 0.1 26 4.3 0.0 3.1 3 0 0 3 3 3 0 Protein phosphatase 2C DUF4148 PF13663.6 CBZ28217.1 - 0.18 12.0 8.3 0.41 10.9 8.3 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4148) zf-RING_2 PF13639.6 CBZ28219.1 - 3.1e-08 33.8 14.6 3.1e-08 33.8 14.6 2.0 2 0 0 2 2 2 1 Ring finger domain zf-rbx1 PF12678.7 CBZ28219.1 - 7.1e-08 32.6 11.4 1.8e-07 31.3 11.4 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_11 PF17123.5 CBZ28219.1 - 2.6e-06 27.0 7.7 5.7e-06 26.0 7.7 1.6 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_UBOX PF13445.6 CBZ28219.1 - 1.3e-05 25.1 7.9 3.2e-05 23.8 7.9 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 CBZ28219.1 - 1.5e-05 24.7 11.7 3.6e-05 23.5 11.7 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 CBZ28219.1 - 5.3e-05 23.2 4.9 0.00012 22.1 4.9 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4 PF00097.25 CBZ28219.1 - 0.0015 18.3 11.2 0.0015 18.3 11.2 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CBZ28219.1 - 0.019 14.9 12.9 0.041 13.9 12.9 1.6 1 0 0 1 1 1 0 zinc-RING finger domain Zn_ribbon_17 PF17120.5 CBZ28219.1 - 0.14 11.8 9.2 0.35 10.5 9.2 1.6 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-C3HC4_3 PF13920.6 CBZ28219.1 - 0.25 11.2 11.1 0.47 10.4 11.1 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) IF-2B PF01008.17 CBZ28220.1 - 1.7e-33 116.1 0.0 2.6e-33 115.4 0.0 1.5 1 1 0 1 1 1 1 Initiation factor 2 subunit family DUF3071 PF11268.8 CBZ28220.1 - 0.16 12.0 2.1 0.22 11.5 1.1 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF3071) AsmA_1 PF13109.6 CBZ28222.1 - 0.17 11.3 0.0 0.32 10.4 0.0 1.4 1 0 0 1 1 1 0 AsmA-like C-terminal region WD40 PF00400.32 CBZ28225.1 - 7.3e-16 58.3 18.3 0.00093 20.0 0.5 5.8 4 1 1 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBZ28225.1 - 0.00014 22.1 0.2 0.52 10.6 0.0 3.8 2 2 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 CBZ28225.1 - 0.032 14.2 0.0 0.29 11.1 0.0 2.6 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat Cpn60_TCP1 PF00118.24 CBZ28226.1 - 2.3e-148 494.9 11.7 2.6e-148 494.7 11.7 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Cation_efflux PF01545.21 CBZ28227.1 - 3.9e-44 150.8 16.0 3.9e-44 150.8 16.0 2.8 2 1 0 2 2 2 1 Cation efflux family UCH PF00443.29 CBZ28228.1 - 1.8e-48 165.3 0.7 2.5e-48 164.8 0.7 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 CBZ28228.1 - 2.2e-15 57.1 2.1 7.6e-15 55.3 2.1 1.9 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DZR PF12773.7 CBZ28228.1 - 0.093 12.8 6.1 0.7 10.0 6.2 2.2 1 1 1 2 2 2 0 Double zinc ribbon zf-CHY PF05495.12 CBZ28228.1 - 1 9.9 6.5 10 6.7 0.7 2.7 1 1 1 2 2 2 0 CHY zinc finger Zn_Tnp_IS1595 PF12760.7 CBZ28228.1 - 1.4 9.0 3.7 25 4.9 0.1 2.7 2 0 0 2 2 2 0 Transposase zinc-ribbon domain zinc-ribbons_6 PF07191.12 CBZ28228.1 - 2.1 8.4 5.9 7.1 6.7 4.2 2.5 1 1 1 2 2 2 0 zinc-ribbons PhnA_Zn_Ribbon PF08274.12 CBZ28228.1 - 2.3 8.2 5.9 4.1 7.5 0.3 2.5 2 0 0 2 2 2 0 PhnA Zinc-Ribbon Ribonucleas_3_3 PF14622.6 CBZ28230.1 - 4e-05 23.8 0.0 0.00049 20.3 0.0 2.1 1 1 0 1 1 1 1 Ribonuclease-III-like vMSA PF00695.19 CBZ28230.1 - 0.057 12.5 0.1 0.074 12.1 0.1 1.2 1 0 0 1 1 1 0 Major surface antigen from hepadnavirus LRR_6 PF13516.6 CBZ28231.1 - 4.2e-19 66.9 16.8 0.0015 18.4 0.0 9.5 10 0 0 10 10 10 7 Leucine Rich repeat LRR_1 PF00560.33 CBZ28231.1 - 1.5e-08 34.0 0.3 1.5 9.7 0.3 7.2 8 1 0 8 8 8 2 Leucine Rich Repeat LRR_8 PF13855.6 CBZ28231.1 - 1.1e-06 28.3 3.4 0.013 15.2 0.3 5.2 3 3 0 3 3 3 2 Leucine rich repeat LRR_4 PF12799.7 CBZ28231.1 - 2.9e-06 27.5 6.7 0.063 13.7 0.2 5.1 5 2 1 6 6 6 3 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 CBZ28231.1 - 0.071 12.6 0.2 0.29 10.6 0.0 2.0 2 0 0 2 2 2 0 Leucine-rich repeat KH_1 PF00013.29 CBZ28233.1 - 1.7e-09 37.4 0.0 3.8e-09 36.2 0.0 1.7 1 0 0 1 1 1 1 KH domain zf-CCCH_4 PF18044.1 CBZ28233.1 - 1.6e-08 34.2 4.9 2.8e-08 33.4 4.9 1.4 1 0 0 1 1 1 1 CCCH-type zinc finger Helicase_C PF00271.31 CBZ28233.1 - 4.5e-05 23.8 0.1 0.00011 22.5 0.1 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-CCCH PF00642.24 CBZ28233.1 - 0.00096 19.0 2.4 0.0025 17.7 2.4 1.7 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 CBZ28233.1 - 0.0033 17.4 3.5 0.007 16.4 3.5 1.6 1 0 0 1 1 1 1 Zinc finger domain zf-CCCH_2 PF14608.6 CBZ28233.1 - 1 10.0 3.0 0.5 10.9 0.5 1.8 2 0 0 2 2 2 0 RNA-binding, Nab2-type zinc finger tRNA-synt_1d PF00750.19 CBZ28234.1 - 7.8e-111 370.4 0.1 4e-66 223.3 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class I (R) DALR_1 PF05746.15 CBZ28234.1 - 5.7e-27 94.3 2.7 7.3e-26 90.7 0.5 2.7 2 0 0 2 2 2 1 DALR anticodon binding domain Arg_tRNA_synt_N PF03485.16 CBZ28234.1 - 8.7e-13 48.7 0.3 2.6e-12 47.1 0.3 1.9 1 0 0 1 1 1 1 Arginyl tRNA synthetase N terminal domain Cupin_8 PF13621.6 CBZ28235.1 - 2.9e-17 63.2 0.1 2.7e-16 60.1 0.1 2.3 1 1 0 1 1 1 1 Cupin-like domain JmjC PF02373.22 CBZ28235.1 - 1e-11 45.2 0.0 2.2e-11 44.2 0.0 1.6 1 0 0 1 1 1 1 JmjC domain, hydroxylase Cupin_4 PF08007.12 CBZ28235.1 - 0.0013 18.3 0.0 0.0026 17.3 0.0 1.5 1 0 0 1 1 1 1 Cupin superfamily protein F-box PF00646.33 CBZ28235.1 - 0.0051 16.7 0.6 0.023 14.6 0.6 2.0 2 0 0 2 2 2 1 F-box domain Cupin_2 PF07883.11 CBZ28235.1 - 0.11 12.2 0.0 0.29 10.9 0.0 1.6 1 0 0 1 1 1 0 Cupin domain F-box-like PF12937.7 CBZ28235.1 - 0.13 12.2 0.7 0.33 10.9 0.7 1.6 1 0 0 1 1 1 0 F-box-like Mo25 PF08569.11 CBZ28236.1 - 0.13 11.6 0.1 0.19 11.1 0.1 1.2 1 0 0 1 1 1 0 Mo25-like Pkinase PF00069.25 CBZ28240.1 - 6.1e-58 196.2 0.0 8.8e-58 195.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ28240.1 - 1e-41 143.0 0.0 1.7e-41 142.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 CBZ28240.1 - 0.0093 15.9 0.0 0.038 13.9 0.0 1.9 1 1 1 2 2 2 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 CBZ28240.1 - 0.015 14.1 0.0 0.035 12.9 0.0 1.5 1 0 0 1 1 1 0 Fungal protein kinase Seadorna_VP7 PF07387.11 CBZ28240.1 - 0.29 10.2 0.1 0.44 9.6 0.1 1.1 1 0 0 1 1 1 0 Seadornavirus VP7 RL10P_insert PF17777.1 CBZ28241.1 - 1.9e-20 72.6 0.2 3.3e-20 71.8 0.2 1.4 1 0 0 1 1 1 1 Insertion domain in 60S ribosomal protein L10P Ribosomal_L10 PF00466.20 CBZ28241.1 - 3.3e-17 62.5 0.1 6.9e-17 61.4 0.1 1.5 1 0 0 1 1 1 1 Ribosomal protein L10 Ribosomal_60s PF00428.19 CBZ28241.1 - 2.9e-14 53.4 3.8 2.9e-14 53.4 3.8 2.3 3 0 0 3 3 3 1 60s Acidic ribosomal protein TraI_2 PF07514.11 CBZ28242.1 - 0.079 11.9 0.0 0.085 11.8 0.0 1.1 1 0 0 1 1 1 0 Putative helicase Choline_kinase PF01633.20 CBZ28244.1 - 4.7e-20 72.1 0.3 1.6e-19 70.4 0.3 1.8 1 1 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.23 CBZ28244.1 - 3.3e-11 43.6 0.2 9.8e-11 42.0 0.2 1.8 1 1 0 1 1 1 1 Phosphotransferase enzyme family Pkinase PF00069.25 CBZ28244.1 - 0.0055 16.1 0.1 0.015 14.6 0.1 1.7 1 1 0 1 1 1 1 Protein kinase domain AlbA_2 PF04326.14 CBZ28245.1 - 3.8e-05 24.0 0.0 6.7e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 Putative DNA-binding domain Snf7 PF03357.21 CBZ28246.1 - 1.4e-33 116.0 34.8 1.4e-33 116.0 34.8 2.0 1 1 1 2 2 2 2 Snf7 CBF PF03914.17 CBZ28247.1 - 3.7e-32 111.7 0.4 3.7e-32 111.7 0.4 2.2 2 0 0 2 2 2 1 CBF/Mak21 family DUF2773 PF10971.8 CBZ28247.1 - 0.11 12.6 0.0 0.24 11.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2773) BUD22 PF09073.10 CBZ28247.1 - 2 7.7 13.2 3.1 7.0 13.2 1.2 1 0 0 1 1 1 0 BUD22 TFIIA PF03153.13 CBZ28247.1 - 5.8 6.8 8.4 10 6.0 8.4 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PCI PF01399.27 CBZ28248.1 - 7.7e-19 68.2 0.1 1.5e-18 67.2 0.1 1.5 1 0 0 1 1 1 1 PCI domain Rpn3_C PF08375.11 CBZ28248.1 - 9.4e-16 58.0 1.3 9.4e-16 58.0 1.3 1.9 2 0 0 2 2 2 1 Proteasome regulatory subunit C-terminal TPR_2 PF07719.17 CBZ28248.1 - 0.073 13.2 0.8 0.22 11.7 0.8 1.9 1 0 0 1 1 1 0 Tetratricopeptide repeat cNMP_binding PF00027.29 CBZ28249.1 - 3.7e-12 46.1 0.1 0.012 15.7 0.0 4.2 3 0 0 3 3 3 3 Cyclic nucleotide-binding domain RRXRR PF14239.6 CBZ28250.1 - 0.12 12.3 2.8 0.28 11.0 2.8 1.6 1 0 0 1 1 1 0 RRXRR protein ATG_C PF09333.11 CBZ28250.1 - 0.27 11.6 1.6 2.5 8.5 0.5 2.6 2 0 0 2 2 2 0 Autophagy-related protein C terminal domain FTCD_C PF04961.12 CBZ28250.1 - 2 8.1 5.2 0.96 9.2 0.7 2.3 2 0 0 2 2 2 0 Formiminotransferase-cyclodeaminase HicB PF05534.12 CBZ28253.1 - 0.098 12.5 0.2 0.23 11.3 0.2 1.6 1 0 0 1 1 1 0 HicB family DUF543 PF04418.12 CBZ28254.1 - 1.4e-21 76.3 0.0 1.8e-21 75.9 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF543) GNAT_acetyltran PF12746.7 CBZ28255.1 - 1.3e-52 178.8 0.0 1.5e-52 178.6 0.0 1.0 1 0 0 1 1 1 1 GNAT acetyltransferase FR47 PF08445.10 CBZ28255.1 - 0.036 14.0 0.0 0.079 12.9 0.0 1.7 1 1 0 1 1 1 0 FR47-like protein RNA_pol_L_2 PF13656.6 CBZ28256.1 - 1.7e-22 79.0 0.0 2.3e-22 78.6 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.24 CBZ28256.1 - 2.2e-05 23.8 0.0 4.2e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain DAGAT PF03982.13 CBZ28257.1 - 3.6e-28 98.3 0.0 7.1e-28 97.4 0.0 1.4 1 0 0 1 1 1 1 Diacylglycerol acyltransferase Aa_trans PF01490.18 CBZ28259.1 - 1.4e-58 198.6 24.7 1.7e-58 198.3 24.7 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 CBZ28259.1 - 1.2e-10 41.0 6.6 2.5e-10 40.0 6.6 1.5 1 0 0 1 1 1 1 Tryptophan/tyrosine permease family DUF4231 PF14015.6 CBZ28259.1 - 0.15 12.5 5.7 2.7 8.5 0.2 3.7 3 1 1 4 4 4 0 Protein of unknown function (DUF4231) CF222 PF15661.5 CBZ28261.1 - 3.5 6.4 24.2 3.5 6.4 24.2 1.0 1 0 0 1 1 1 0 C6orf222, uncharacterised family IF4E PF01652.18 CBZ28262.1 - 2.1e-46 157.6 0.3 2.5e-46 157.4 0.3 1.0 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E WD40 PF00400.32 CBZ28263.1 - 6.3e-07 30.0 1.0 8.6 7.4 0.0 5.9 5 1 0 5 5 5 4 WD domain, G-beta repeat BRO1 PF03097.18 CBZ28264.1 - 4.4e-60 203.5 1.7 4.4e-60 203.5 1.7 2.0 2 0 0 2 2 2 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.6 CBZ28264.1 - 2.5e-32 112.4 9.2 2.5e-32 112.4 9.2 2.6 2 1 1 3 3 3 1 ALIX V-shaped domain binding to HIV DHHA2 PF02833.14 CBZ28264.1 - 0.075 13.2 3.0 1.3 9.2 0.2 3.2 4 0 0 4 4 4 0 DHHA2 domain kleA_kleC PF17383.2 CBZ28264.1 - 1.3 9.4 6.0 19 5.7 0.1 3.4 2 0 0 2 2 2 0 Uncharacterized KorC regulated protein A DUF948 PF06103.11 CBZ28264.1 - 2.2 8.6 8.6 2.5 8.4 0.3 4.1 3 1 0 3 3 3 0 Bacterial protein of unknown function (DUF948) IFT20 PF14931.6 CBZ28264.1 - 8.7 6.5 20.2 0.046 13.9 7.2 3.4 2 1 0 2 2 2 0 Intraflagellar transport complex B, subunit 20 Strumpellin PF10266.9 CBZ28266.1 - 0 1336.2 0.0 0 1336.1 0.0 1.0 1 0 0 1 1 1 1 Hereditary spastic paraplegia protein strumpellin ThiF PF00899.21 CBZ28267.1 - 2.7e-61 207.0 0.0 4e-61 206.5 0.0 1.1 1 0 0 1 1 1 1 ThiF family Rhodanese PF00581.20 CBZ28267.1 - 0.0015 19.1 0.0 0.0047 17.4 0.0 1.9 2 0 0 2 2 2 1 Rhodanese-like domain Sacchrp_dh_NADP PF03435.18 CBZ28267.1 - 0.0023 18.2 0.2 0.0043 17.3 0.2 1.5 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Shikimate_DH PF01488.20 CBZ28267.1 - 0.025 14.6 0.3 0.057 13.5 0.1 1.7 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase 3HCDH_N PF02737.18 CBZ28267.1 - 0.076 12.9 0.0 0.13 12.1 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.14 CBZ28267.1 - 0.11 12.0 0.0 0.18 11.4 0.0 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Se-cys_synth_N PF12390.8 CBZ28267.1 - 2.6 8.4 0.0 2.6 8.4 0.0 3.3 5 0 0 5 5 5 0 Selenocysteine synthase N terminal LRR_9 PF14580.6 CBZ28268.1 - 0.00015 21.3 0.1 0.00033 20.2 0.1 1.5 1 0 0 1 1 1 1 Leucine-rich repeat LRR_4 PF12799.7 CBZ28269.1 - 0.00044 20.6 0.1 0.0025 18.2 0.0 2.3 2 0 0 2 2 2 1 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CBZ28269.1 - 0.014 15.2 0.2 0.037 13.8 0.2 1.8 1 1 0 1 1 1 0 Leucine rich repeat LRR_9 PF14580.6 CBZ28269.1 - 0.027 14.0 0.0 0.056 13.0 0.0 1.5 1 0 0 1 1 1 0 Leucine-rich repeat zf-CCCH PF00642.24 CBZ28269.1 - 0.096 12.6 5.9 0.056 13.4 2.6 2.1 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 CBZ28269.1 - 0.14 12.0 2.0 0.43 10.4 2.0 1.9 1 0 0 1 1 1 0 CCCH-type zinc finger zf_CCCH_4 PF18345.1 CBZ28269.1 - 0.51 10.5 6.1 0.1 12.7 1.1 2.4 2 1 0 2 2 2 0 Zinc finger domain zf-CCCH_2 PF14608.6 CBZ28269.1 - 0.76 10.3 7.8 0.1 13.1 3.1 2.0 2 0 0 2 2 2 0 RNA-binding, Nab2-type zinc finger eRF1_2 PF03464.15 CBZ28271.1 - 7.6e-41 139.5 0.0 1.5e-40 138.6 0.0 1.5 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.15 CBZ28271.1 - 1.1e-37 129.0 1.8 1.4e-37 128.6 0.5 1.9 2 0 0 2 2 2 1 eRF1 domain 3 eRF1_1 PF03463.15 CBZ28271.1 - 2.4e-12 46.9 0.0 4.2e-12 46.2 0.0 1.4 1 0 0 1 1 1 1 eRF1 domain 1 baeRF_family10 PF18854.1 CBZ28271.1 - 1.1e-09 38.7 0.0 1.9e-09 37.9 0.0 1.4 1 0 0 1 1 1 1 Bacterial archaeo-eukaryotic release factor family 10 acVLRF1 PF18859.1 CBZ28271.1 - 1.6e-09 38.1 0.0 2.5e-09 37.5 0.0 1.3 1 0 0 1 1 1 1 Actinobacteria/chloroflexi VLRF1 release factor HlyD_2 PF12700.7 CBZ28273.1 - 0.02 13.7 1.2 0.028 13.2 1.2 1.3 1 0 0 1 1 1 0 HlyD family secretion protein AAA_6 PF12774.7 CBZ28275.1 - 1.9e-123 411.6 0.0 4.1e-123 410.5 0.0 1.6 1 0 0 1 1 1 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 CBZ28275.1 - 7.6e-111 371.0 6.5 7.6e-111 371.0 6.5 4.4 4 0 0 4 4 4 2 Dynein heavy chain, N-terminal region 2 AAA_9 PF12781.7 CBZ28275.1 - 1.7e-61 207.2 3.8 1.7e-61 207.2 3.8 2.6 2 0 0 2 2 1 1 ATP-binding dynein motor region AAA_8 PF12780.7 CBZ28275.1 - 1.4e-47 162.2 0.3 3e-46 157.8 0.0 2.8 2 0 0 2 2 2 1 P-loop containing dynein motor region D4 AAA_5 PF07728.14 CBZ28275.1 - 3.1e-31 108.2 0.0 3.6e-20 72.4 0.0 5.7 4 1 0 4 4 4 4 AAA domain (dynein-related subfamily) AAA_lid_11 PF18198.1 CBZ28275.1 - 7.1e-31 107.2 0.0 1.5e-30 106.2 0.0 1.6 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain AAA_7 PF12775.7 CBZ28275.1 - 1.1e-29 103.2 0.0 2e-23 82.9 0.0 4.4 4 0 0 4 4 4 2 P-loop containing dynein motor region Dynein_heavy PF03028.15 CBZ28275.1 - 3.8e-27 94.7 0.6 2.9e-26 91.9 0.0 2.8 3 0 0 3 3 2 1 Dynein heavy chain region D6 P-loop domain Dynein_C PF18199.1 CBZ28275.1 - 2.2e-24 86.3 0.0 2.2e-24 86.3 0.0 4.3 4 0 0 4 4 4 1 Dynein heavy chain C-terminal domain MT PF12777.7 CBZ28275.1 - 1.4e-22 80.2 8.6 2.6e-22 79.3 8.6 1.4 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_16 PF13191.6 CBZ28275.1 - 1.9e-13 51.2 8.2 0.0011 19.4 0.0 8.2 7 1 1 8 8 8 2 AAA ATPase domain AAA_22 PF13401.6 CBZ28275.1 - 1.1e-10 41.9 2.7 0.16 12.2 0.0 6.6 6 0 0 6 6 5 3 AAA domain AAA PF00004.29 CBZ28275.1 - 1.2e-08 35.5 0.1 0.15 12.5 0.0 6.2 6 0 0 6 6 4 1 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 CBZ28275.1 - 7.2e-07 29.6 0.3 0.74 10.2 0.0 5.0 5 0 0 5 5 5 1 RNA helicase RsgA_GTPase PF03193.16 CBZ28275.1 - 1e-05 25.5 3.0 0.00018 21.5 0.0 3.8 4 0 0 4 4 3 1 RsgA GTPase AAA_30 PF13604.6 CBZ28275.1 - 6.8e-05 22.7 0.2 0.041 13.6 0.0 3.3 2 0 0 2 2 2 1 AAA domain ABC_tran PF00005.27 CBZ28275.1 - 7.7e-05 23.2 3.3 0.0014 19.1 0.0 4.2 4 0 0 4 4 2 1 ABC transporter AAA_24 PF13479.6 CBZ28275.1 - 0.0001 22.1 0.0 0.13 11.9 0.0 3.1 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 CBZ28275.1 - 0.00054 20.5 0.0 0.13 12.8 0.0 3.8 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.6 CBZ28275.1 - 0.00084 19.6 0.0 0.00084 19.6 0.0 4.3 5 0 0 5 5 2 1 AAA domain AAA_29 PF13555.6 CBZ28275.1 - 0.0017 18.1 0.8 0.025 14.3 0.0 3.3 4 0 0 4 4 4 1 P-loop containing region of AAA domain T2SSE PF00437.20 CBZ28275.1 - 0.003 16.7 0.3 0.026 13.6 0.0 2.6 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_21 PF13304.6 CBZ28275.1 - 0.015 15.1 0.0 0.033 14.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_lid_7 PF17867.1 CBZ28275.1 - 0.018 15.2 0.0 0.079 13.2 0.0 2.2 1 0 0 1 1 1 0 Midasin AAA lid domain Rad17 PF03215.15 CBZ28275.1 - 0.027 14.4 1.8 0.69 9.8 0.1 4.1 5 0 0 5 5 5 0 Rad17 P-loop domain AAA_33 PF13671.6 CBZ28275.1 - 0.035 14.3 3.7 0.19 11.9 0.0 4.3 5 0 0 5 5 4 0 AAA domain PhoH PF02562.16 CBZ28275.1 - 0.096 12.1 0.7 0.64 9.4 0.0 2.6 2 0 0 2 2 2 0 PhoH-like protein ATP_bind_1 PF03029.17 CBZ28275.1 - 0.12 12.1 0.1 7.9 6.2 0.0 3.2 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein ATPase_2 PF01637.18 CBZ28275.1 - 0.53 10.2 8.3 0.83 9.5 0.0 3.8 5 0 0 5 5 2 0 ATPase domain predominantly from Archaea AAA_23 PF13476.6 CBZ28275.1 - 1.9 9.0 0.0 1.9 9.0 0.0 5.5 5 0 0 5 5 4 0 AAA domain NACHT PF05729.12 CBZ28275.1 - 4.7 7.1 6.6 2.5 8.0 0.0 3.9 5 0 0 5 5 3 0 NACHT domain TBCC PF07986.12 CBZ28276.1 - 3e-24 85.1 4.1 6.1e-18 64.7 6.0 2.4 2 0 0 2 2 2 2 Tubulin binding cofactor C Frag1 PF10277.9 CBZ28277.1 - 5.6e-35 120.9 12.7 5.6e-35 120.9 12.7 3.5 3 1 0 3 3 3 1 Frag1/DRAM/Sfk1 family Exo_endo_phos PF03372.23 CBZ28277.1 - 0.069 12.7 0.0 0.14 11.6 0.0 1.5 1 0 0 1 1 1 0 Endonuclease/Exonuclease/phosphatase family Pkinase PF00069.25 CBZ28278.1 - 3.8e-25 88.8 0.0 7.5e-18 64.8 0.0 2.1 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ28278.1 - 9.3e-12 44.8 0.2 2.4e-11 43.4 0.2 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CBZ28278.1 - 2e-08 33.4 0.3 2.8e-08 33.0 0.3 1.1 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 CBZ28278.1 - 5.5e-05 23.2 0.0 9.6e-05 22.4 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 CBZ28278.1 - 0.00029 20.3 0.1 0.00054 19.4 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 CBZ28278.1 - 0.00077 19.1 1.8 0.0022 17.6 0.1 2.0 1 1 0 2 2 2 1 RIO1 family Choline_kinase PF01633.20 CBZ28278.1 - 0.073 12.6 0.1 0.18 11.4 0.1 1.6 1 1 0 1 1 1 0 Choline/ethanolamine kinase Pox_ser-thr_kin PF05445.11 CBZ28278.1 - 0.29 10.1 0.0 0.41 9.5 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase GTP_cyclohydroI PF01227.22 CBZ28279.1 - 0.07 12.5 0.0 0.15 11.4 0.0 1.5 1 0 0 1 1 1 0 GTP cyclohydrolase I Pkinase PF00069.25 CBZ28280.1 - 7.9e-39 133.6 0.0 1e-38 133.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ28280.1 - 1.6e-17 63.6 0.0 2.4e-17 63.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CBZ28280.1 - 0.014 14.2 0.0 0.035 12.9 0.0 1.6 1 0 0 1 1 1 0 Fungal protein kinase PEPCK_ATP PF01293.20 CBZ28281.1 - 1.1e-194 647.4 0.0 1.4e-194 647.1 0.0 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase DUF4914 PF16260.5 CBZ28281.1 - 0.018 13.2 0.1 0.043 11.9 0.0 1.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4914) AAA_33 PF13671.6 CBZ28281.1 - 0.14 12.3 0.0 0.26 11.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain PEPCK_ATP PF01293.20 CBZ28282.1 - 6.8e-131 437.1 0.0 8.1e-131 436.9 0.0 1.1 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase AAA_33 PF13671.6 CBZ28282.1 - 0.086 13.0 0.0 0.14 12.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain PEPCK_ATP PF01293.20 CBZ28283.1 - 6e-194 645.0 0.0 7.7e-194 644.7 0.0 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase DUF4914 PF16260.5 CBZ28283.1 - 0.018 13.2 0.1 0.049 11.7 0.0 1.7 2 1 0 2 2 2 0 Domain of unknown function (DUF4914) AAA_33 PF13671.6 CBZ28283.1 - 0.14 12.4 0.0 0.26 11.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain TSC22 PF01166.18 CBZ28284.1 - 0.02 15.2 43.3 4.6 7.6 0.1 12.5 9 2 3 12 12 12 0 TSC-22/dip/bun family Apo-CII PF05355.11 CBZ28284.1 - 0.23 11.6 8.7 32 4.8 0.2 4.0 3 0 0 3 3 3 0 Apolipoprotein C-II YchF-GTPase_C PF06071.13 CBZ28285.1 - 4.1e-25 87.8 0.1 9.9e-25 86.6 0.1 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF933) MMR_HSR1 PF01926.23 CBZ28285.1 - 8.2e-21 74.2 0.0 1.9e-20 73.1 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 CBZ28285.1 - 1.3e-07 31.3 0.0 2.4e-07 30.4 0.0 1.5 1 0 0 1 1 1 1 Ferrous iron transport protein B TGS PF02824.21 CBZ28285.1 - 0.00082 19.4 0.0 0.0016 18.5 0.0 1.5 1 0 0 1 1 1 1 TGS domain ABC_tran PF00005.27 CBZ28285.1 - 0.017 15.6 0.0 0.04 14.4 0.0 1.7 1 1 0 1 1 1 0 ABC transporter MeaB PF03308.16 CBZ28285.1 - 0.049 12.6 0.0 0.095 11.7 0.0 1.4 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB DUF3801 PF12687.7 CBZ28285.1 - 0.093 12.8 1.0 0.18 11.9 1.1 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3801) ICA69 PF04629.14 CBZ28285.1 - 0.096 13.0 0.2 0.15 12.3 0.2 1.2 1 0 0 1 1 1 0 Islet cell autoantigen ICA69, C-terminal domain RsgA_GTPase PF03193.16 CBZ28285.1 - 0.14 12.0 0.1 0.71 9.8 0.0 2.1 3 0 0 3 3 3 0 RsgA GTPase DSPc PF00782.20 CBZ28286.1 - 7.5e-23 80.8 0.0 1.1e-22 80.2 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 CBZ28286.1 - 0.0014 18.3 0.0 0.0023 17.5 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Flagellar_rod PF05149.12 CBZ28287.1 - 5.9e-107 357.4 22.4 5.9e-107 357.4 22.4 1.8 2 0 0 2 2 2 1 Paraflagellar rod protein SH3_9 PF14604.6 CBZ28287.1 - 2.4e-12 46.5 0.0 5.1e-12 45.5 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 CBZ28287.1 - 4.9e-10 38.9 0.0 8.9e-10 38.0 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 CBZ28287.1 - 2.2e-09 36.8 0.0 4e-09 36.0 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain Mlp PF03304.13 CBZ28287.1 - 0.007 16.6 2.1 0.63 10.3 1.1 2.7 2 0 0 2 2 2 1 Mlp lipoprotein family Rb_C PF08934.10 CBZ28287.1 - 0.015 15.1 0.7 0.045 13.6 0.4 2.0 2 0 0 2 2 2 0 Rb C-terminal domain Cnl2_NKP2 PF09447.10 CBZ28287.1 - 0.043 14.0 4.1 0.094 12.9 0.9 3.3 3 0 0 3 3 3 0 Cnl2/NKP2 family protein RRT14 PF17075.5 CBZ28287.1 - 0.68 10.0 7.3 0.065 13.3 2.0 2.0 2 0 0 2 2 2 0 Regular of rDNA transcription protein 14 FKBP_N PF01346.18 CBZ28287.1 - 2.6 9.1 11.0 0.1 13.6 2.6 2.9 3 0 0 3 3 3 0 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase GSP_synth PF03738.14 CBZ28289.1 - 8.8e-71 239.1 0.0 1.2e-70 238.7 0.0 1.1 1 0 0 1 1 1 1 Glutathionylspermidine synthase preATP-grasp CHAP PF05257.16 CBZ28289.1 - 4.1e-11 43.3 0.0 1.3e-10 41.7 0.0 1.9 1 0 0 1 1 1 1 CHAP domain YCII PF03795.14 CBZ28290.1 - 0.04 14.3 0.1 0.11 12.9 0.1 1.7 1 0 0 1 1 1 0 YCII-related domain Mre11_DNA_bind PF04152.14 CBZ28291.1 - 1.1e-26 94.2 0.0 2.7e-26 92.9 0.0 1.7 2 0 0 2 2 2 1 Mre11 DNA-binding presumed domain Metallophos PF00149.28 CBZ28291.1 - 8.2e-14 52.6 0.3 1.5e-13 51.7 0.3 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 CBZ28291.1 - 0.0017 18.6 0.0 0.026 14.7 0.0 2.7 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain PSD5 PF07637.11 CBZ28292.1 - 0.0035 17.7 0.0 0.017 15.5 0.0 2.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1595) DICT PF10069.9 CBZ28292.1 - 0.11 12.2 0.3 0.87 9.4 0.0 2.4 3 0 0 3 3 3 0 Sensory domain in DIguanylate Cyclases and Two-component system DUF846 PF05832.12 CBZ28293.1 - 5.9e-21 75.0 3.6 7.2e-21 74.7 3.6 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF846) TM1586_NiRdase PF14512.6 CBZ28294.1 - 0.056 13.0 0.1 0.092 12.3 0.1 1.4 1 1 0 1 1 1 0 Putative TM nitroreductase DUF4064 PF13273.6 CBZ28296.1 - 0.075 13.3 0.3 0.075 13.3 0.3 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF4064) TMEM52 PF14979.6 CBZ28296.1 - 0.27 11.1 0.2 0.27 11.1 0.2 2.1 2 0 0 2 2 2 0 Transmembrane 52 NS3_envE PF02723.14 CBZ28296.1 - 2.7 8.1 7.5 0.93 9.6 0.1 3.0 3 0 0 3 3 3 0 Non-structural protein NS3/Small envelope protein E Pkinase PF00069.25 CBZ28298.1 - 2.5e-45 154.9 0.0 1.6e-41 142.4 0.0 3.1 3 1 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ28298.1 - 9.1e-23 80.9 0.0 2.1e-21 76.4 0.0 2.4 2 1 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 CBZ28298.1 - 7.4e-07 28.8 0.0 1.3e-06 28.0 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 CBZ28298.1 - 0.00068 18.7 0.0 0.0011 18.0 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain CCDC142 PF14923.6 CBZ28298.1 - 0.08 11.7 0.4 0.18 10.5 0.4 1.5 1 0 0 1 1 1 0 Coiled-coil protein 142 Pkinase_fungal PF17667.1 CBZ28298.1 - 0.15 10.8 0.0 0.29 9.8 0.0 1.4 1 0 0 1 1 1 0 Fungal protein kinase Dpy-30 PF05186.13 CBZ28299.1 - 4.2e-06 26.3 0.1 7.6e-06 25.5 0.1 1.4 1 0 0 1 1 1 1 Dpy-30 motif Hydin_ADK PF17213.3 CBZ28299.1 - 0.0042 17.4 0.8 0.0042 17.4 0.8 2.8 2 0 0 2 2 2 1 Hydin Adenylate kinase-like domain IFT43 PF15305.6 CBZ28300.1 - 9.7e-06 25.8 3.8 3.6e-05 24.0 3.8 2.1 1 1 0 1 1 1 1 Intraflagellar transport protein 43 LSM PF01423.22 CBZ28301.1 - 1.5e-17 63.0 0.4 1.9e-17 62.7 0.4 1.1 1 0 0 1 1 1 1 LSM domain FtsJ PF01728.19 CBZ28302.1 - 9.9e-57 191.9 0.0 1.5e-56 191.3 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase DUF3381 PF11861.8 CBZ28302.1 - 2.4e-30 105.5 5.6 2.4e-30 105.5 5.6 4.8 4 1 0 4 4 4 1 Domain of unknown function (DUF3381) Spb1_C PF07780.12 CBZ28302.1 - 3.1e-30 105.4 18.8 3.1e-30 105.4 18.8 3.4 3 1 0 3 3 3 1 Spb1 C-terminal domain TrmB PF01978.19 CBZ28302.1 - 0.018 14.9 0.2 0.054 13.4 0.2 1.9 1 1 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB RabGAP-TBC PF00566.18 CBZ28303.1 - 3.1e-29 102.2 0.0 3.3e-15 56.3 0.0 3.4 3 0 0 3 3 3 3 Rab-GTPase-TBC domain GMP_PDE_delta PF05351.11 CBZ28304.1 - 1.1e-62 210.8 0.1 1.3e-62 210.6 0.1 1.0 1 0 0 1 1 1 1 GMP-PDE, delta subunit Cgr1 PF03879.14 CBZ28305.1 - 0.24 11.8 4.5 0.39 11.1 4.5 1.2 1 0 0 1 1 1 0 Cgr1 family FOXP-CC PF16159.5 CBZ28305.1 - 1.9 9.2 4.7 4.1 8.1 4.4 1.7 1 1 0 1 1 1 0 FOXP coiled-coil domain FAD-oxidase_C PF02913.19 CBZ28306.1 - 1.8e-37 129.4 0.1 2.5e-37 128.9 0.1 1.2 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 CBZ28306.1 - 1.5e-35 121.9 1.1 3.4e-35 120.8 1.1 1.6 1 0 0 1 1 1 1 FAD binding domain OTCace PF00185.24 CBZ28306.1 - 0.17 12.0 0.4 17 5.5 0.2 2.5 2 0 0 2 2 2 0 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain Aminotran_4 PF01063.19 CBZ28307.1 - 9.9e-28 97.5 0.0 1.3e-27 97.1 0.0 1.2 1 0 0 1 1 1 1 Amino-transferase class IV Aminotran_4 PF01063.19 CBZ28308.1 - 9.9e-28 97.5 0.0 1.3e-27 97.1 0.0 1.2 1 0 0 1 1 1 1 Amino-transferase class IV Aminotran_4 PF01063.19 CBZ28309.1 - 1e-27 97.5 0.0 1.4e-27 97.1 0.0 1.2 1 0 0 1 1 1 1 Amino-transferase class IV Erv26 PF04148.13 CBZ28310.1 - 1.2e-19 71.0 12.5 9.8e-19 68.0 12.6 1.9 1 1 0 1 1 1 1 Transmembrane adaptor Erv26 Ribonuc_red_sm PF00268.21 CBZ28311.1 - 2.3e-111 371.7 0.1 2.9e-111 371.4 0.1 1.0 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain OCRE PF17780.1 CBZ28313.1 - 0.0001 22.2 3.1 0.00022 21.2 3.1 1.4 1 0 0 1 1 1 1 OCRE domain RRM_1 PF00076.22 CBZ28316.1 - 2.4e-34 117.0 0.0 2.9e-11 43.0 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 CBZ28316.1 - 8.8e-09 35.2 0.1 0.0069 16.4 0.0 3.3 3 0 0 3 3 3 3 Nup53/35/40-type RNA recognition motif RRM_occluded PF16842.5 CBZ28316.1 - 2.9e-07 30.3 0.0 0.0022 17.8 0.0 2.6 3 0 0 3 3 3 2 Occluded RNA-recognition motif RRM_7 PF16367.5 CBZ28316.1 - 0.00052 20.1 0.1 0.54 10.4 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif zf-CCHC PF00098.23 CBZ28316.1 - 0.00072 19.5 0.5 0.0016 18.4 0.5 1.7 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_5 PF14787.6 CBZ28316.1 - 0.032 13.9 2.2 0.032 13.9 2.2 1.9 2 0 0 2 2 2 0 GAG-polyprotein viral zinc-finger zf-CCHC_3 PF13917.6 CBZ28316.1 - 0.047 13.7 1.9 0.099 12.6 1.9 1.5 1 0 0 1 1 1 0 Zinc knuckle PHM7_cyt PF14703.6 CBZ28316.1 - 0.063 13.5 0.1 9.2 6.5 0.0 3.4 2 1 1 3 3 3 0 Cytosolic domain of 10TM putative phosphate transporter Lipase_3 PF01764.25 CBZ28317.1 - 8.9e-13 48.3 0.0 1.2e-10 41.5 0.0 2.5 2 0 0 2 2 2 2 Lipase (class 3) Hydrolase_4 PF12146.8 CBZ28317.1 - 0.024 13.9 0.0 0.048 12.9 0.0 1.4 1 0 0 1 1 1 0 Serine aminopeptidase, S33 DUF2974 PF11187.8 CBZ28317.1 - 0.19 11.2 0.0 1.7 8.2 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2974) Motile_Sperm PF00635.26 CBZ28318.1 - 2.2e-06 27.5 0.1 8.8e-06 25.5 0.1 2.1 2 1 0 2 2 2 1 MSP (Major sperm protein) domain Transferase PF02458.15 CBZ28318.1 - 0.089 11.4 0.0 0.13 10.9 0.0 1.2 1 0 0 1 1 1 0 Transferase family PI3_PI4_kinase PF00454.27 CBZ28320.1 - 3.8e-20 72.7 0.0 1.3e-19 71.0 0.0 1.9 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase DUF1465 PF07323.12 CBZ28320.1 - 0.022 14.6 0.4 0.044 13.6 0.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1465) WD40 PF00400.32 CBZ28323.1 - 6.7e-11 42.6 4.6 0.0093 16.8 0.2 7.0 8 0 0 8 8 8 3 WD domain, G-beta repeat Ge1_WD40 PF16529.5 CBZ28323.1 - 0.065 12.2 0.4 0.19 10.7 0.0 1.9 2 0 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein PKcGMP_CC PF16808.5 CBZ28323.1 - 9.8 6.1 11.1 1 9.2 2.2 3.7 3 0 0 3 3 3 0 Coiled-coil N-terminus of cGMP-dependent protein kinase NIF PF03031.18 CBZ28324.1 - 7.3e-26 90.8 0.0 1.1e-25 90.2 0.0 1.3 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase VKOR PF07884.14 CBZ28325.1 - 4.9e-18 65.5 19.0 5.8e-18 65.3 19.0 1.1 1 0 0 1 1 1 1 Vitamin K epoxide reductase family Thioredoxin PF00085.20 CBZ28326.1 - 5.3e-06 26.4 0.0 9.9e-06 25.5 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin Phosducin PF02114.16 CBZ28326.1 - 8.8e-05 21.6 0.1 0.00012 21.1 0.1 1.2 1 0 0 1 1 1 1 Phosducin DUF5089 PF17002.5 CBZ28326.1 - 0.11 12.4 2.7 0.98 9.3 2.7 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF5089) DSPc PF00782.20 CBZ28327.1 - 2.6e-26 92.0 0.0 3.7e-26 91.5 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 CBZ28327.1 - 0.008 15.8 0.0 0.013 15.1 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Ribosomal_L11_N PF03946.14 CBZ28328.1 - 1.7e-15 56.6 0.0 3e-15 55.8 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.19 CBZ28328.1 - 8.1e-15 55.1 0.0 1.4e-14 54.4 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain Stb3 PF10330.9 CBZ28329.1 - 0.017 15.1 0.1 5.2 7.2 0.0 2.9 3 0 0 3 3 3 0 Putative Sin3 binding protein DZR PF12773.7 CBZ28329.1 - 3.5 7.7 53.8 0.032 14.3 5.0 6.2 5 1 1 6 6 6 0 Double zinc ribbon Atg14 PF10186.9 CBZ28330.1 - 8.9e-06 25.0 2.7 1.5e-05 24.2 2.7 1.3 1 0 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 Apt1 PF10351.9 CBZ28330.1 - 1 8.2 3.5 1.4 7.7 3.5 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain EMG1 PF03587.14 CBZ28331.1 - 7.2e-39 133.4 0.0 9e-39 133.1 0.0 1.0 1 0 0 1 1 1 1 EMG1/NEP1 methyltransferase Pex2_Pex12 PF04757.14 CBZ28332.1 - 0.21 11.2 0.0 0.38 10.3 0.0 1.5 1 0 0 1 1 1 0 Pex2 / Pex12 amino terminal region Tropomyosin PF00261.20 CBZ28333.1 - 0.029 13.7 0.3 0.06 12.7 0.3 1.5 1 0 0 1 1 1 0 Tropomyosin Fam20C PF06702.12 CBZ28333.1 - 0.091 12.6 0.1 0.15 11.8 0.1 1.2 1 0 0 1 1 1 0 Golgi casein kinase, C-terminal, Fam20 Mcp5_PH PF12814.7 CBZ28334.1 - 1.5e-15 57.4 0.1 2.1e-15 56.9 0.1 1.1 1 0 0 1 1 1 1 Meiotic cell cortex C-terminal pleckstrin homology PH PF00169.29 CBZ28334.1 - 3.6e-06 27.4 0.6 4.8e-06 27.0 0.6 1.1 1 0 0 1 1 1 1 PH domain PH_2 PF08458.10 CBZ28334.1 - 0.13 12.6 0.4 0.26 11.7 0.0 1.6 2 0 0 2 2 2 0 Plant pleckstrin homology-like region ACOX PF01756.19 CBZ28335.1 - 6.8e-10 38.8 0.0 1.6e-09 37.5 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA oxidase Spt5-NGN PF03439.13 CBZ28336.1 - 2.6e-21 75.3 1.0 8.1e-21 73.7 0.1 2.3 3 0 0 3 3 3 1 Early transcription elongation factor of RNA pol II, NGN section KOW PF00467.29 CBZ28336.1 - 3.7e-07 29.9 5.4 0.077 13.0 0.1 4.7 4 0 0 4 4 4 2 KOW motif HAS-barrel PF09378.10 CBZ28336.1 - 0.0047 17.0 0.5 1.2 9.4 0.0 3.1 3 0 0 3 3 3 1 HAS barrel domain DUF4849 PF16141.5 CBZ28336.1 - 0.074 12.3 0.1 0.72 9.1 0.1 2.0 2 0 0 2 2 2 0 Putative glycoside hydrolase Family 18, chitinase_18 Hormone_3 PF00159.18 CBZ28336.1 - 0.83 9.8 2.9 12 6.1 0.4 2.7 2 0 0 2 2 2 0 Pancreatic hormone peptide MORN PF02493.20 CBZ28337.1 - 2.6e-20 71.0 17.6 7.6e-08 31.8 0.1 5.8 6 1 0 6 6 6 4 MORN repeat PP2C PF00481.21 CBZ28339.1 - 1.8e-76 257.2 0.0 2.2e-76 256.9 0.0 1.0 1 0 0 1 1 1 1 Protein phosphatase 2C SCRL PF06876.12 CBZ28339.1 - 0.065 13.4 0.2 0.2 11.9 0.2 1.8 1 0 0 1 1 1 0 Plant self-incompatibility response (SCRL) protein YchF-GTPase_C PF06071.13 CBZ28340.1 - 9.7e-38 128.2 0.5 2.5e-37 126.9 0.5 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF933) MMR_HSR1 PF01926.23 CBZ28340.1 - 6.9e-22 77.7 0.0 4.1e-21 75.2 0.0 2.1 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 CBZ28340.1 - 0.00021 20.8 0.0 0.00055 19.5 0.0 1.7 2 0 0 2 2 2 1 Ferrous iron transport protein B TGS PF02824.21 CBZ28340.1 - 0.016 15.3 0.0 0.034 14.2 0.0 1.6 1 0 0 1 1 1 0 TGS domain MeaB PF03308.16 CBZ28340.1 - 0.037 13.0 0.0 0.059 12.3 0.0 1.3 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_18 PF13238.6 CBZ28340.1 - 0.037 14.6 0.0 0.15 12.6 0.0 2.0 2 0 0 2 2 2 0 AAA domain Roc PF08477.13 CBZ28340.1 - 0.04 14.1 0.0 0.91 9.8 0.0 2.4 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Dynamin_N PF00350.23 CBZ28340.1 - 0.062 13.4 0.1 14 5.7 0.1 2.7 1 1 1 2 2 2 0 Dynamin family Cpn60_TCP1 PF00118.24 CBZ28342.1 - 0.014 14.1 0.0 0.021 13.5 0.0 1.2 1 0 0 1 1 1 0 TCP-1/cpn60 chaperonin family Glyco_hydro_32N PF00251.20 CBZ28343.1 - 1e-80 271.6 2.6 1.2e-80 271.3 2.6 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 N-terminal domain Glyco_hydro_32C PF08244.12 CBZ28343.1 - 2.2e-19 70.0 0.0 3.2e-19 69.5 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 C terminal RcnB PF11776.8 CBZ28343.1 - 0.058 13.5 1.0 4.1 7.5 0.0 3.3 3 0 0 3 3 3 0 Nickel/cobalt transporter regulator Synaptobrevin PF00957.21 CBZ28344.1 - 3.5e-21 74.8 0.1 5.2e-21 74.2 0.1 1.3 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.6 CBZ28344.1 - 4.4e-10 39.5 0.1 8.8e-10 38.5 0.1 1.5 1 0 0 1 1 1 1 Regulated-SNARE-like domain DUF1424 PF07232.11 CBZ28345.1 - 0.055 12.4 0.2 0.32 9.9 0.1 2.0 1 1 1 2 2 2 0 Putative rep protein (DUF1424) HHV-5_US34A PF17087.5 CBZ28346.1 - 0.12 12.5 3.0 0.27 11.4 2.0 2.1 2 1 0 2 2 2 0 Herpesvirus US34A protein family GWT1 PF06423.12 CBZ28347.1 - 1.2 9.2 6.4 0.85 9.7 4.8 1.6 1 1 1 2 2 2 0 GWT1 RPAP3_C PF13877.6 CBZ28348.1 - 5.3e-14 52.5 0.1 1.1e-13 51.5 0.1 1.6 1 0 0 1 1 1 1 Potential Monad-binding region of RPAP3 TPR_1 PF00515.28 CBZ28348.1 - 6.2e-14 51.1 4.0 2.9e-05 23.7 0.8 3.9 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 CBZ28348.1 - 3.8e-12 45.3 10.3 7.5e-05 22.6 1.9 4.4 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_8 PF13181.6 CBZ28348.1 - 4.5e-09 35.8 3.0 0.0008 19.4 0.4 4.4 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_11 PF13414.6 CBZ28348.1 - 1.1e-07 31.4 2.6 0.00024 20.7 0.0 3.7 3 2 1 4 4 4 2 TPR repeat TPR_9 PF13371.6 CBZ28348.1 - 2.8e-05 24.2 1.5 2.8e-05 24.2 1.5 4.6 3 1 2 5 5 4 2 Tetratricopeptide repeat TPR_17 PF13431.6 CBZ28348.1 - 0.00022 21.4 1.1 0.87 10.1 0.1 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 CBZ28348.1 - 0.00027 21.5 5.0 0.0057 17.4 3.3 4.9 5 1 0 5 5 4 2 Tetratricopeptide repeat TPR_19 PF14559.6 CBZ28348.1 - 0.0059 17.1 0.0 0.0059 17.1 0.0 3.8 4 0 0 4 4 2 2 Tetratricopeptide repeat TPR_16 PF13432.6 CBZ28348.1 - 0.0061 17.2 0.1 0.0061 17.2 0.1 5.3 5 1 1 6 6 5 2 Tetratricopeptide repeat TPR_7 PF13176.6 CBZ28348.1 - 0.037 14.1 7.0 17 5.8 0.4 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_12 PF13424.6 CBZ28348.1 - 0.05 13.9 13.6 0.099 12.9 4.7 4.0 3 1 0 3 3 3 0 Tetratricopeptide repeat ANAPC3 PF12895.7 CBZ28348.1 - 0.44 10.8 3.4 0.67 10.2 0.4 2.4 1 1 1 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.6 CBZ28348.1 - 0.84 10.4 17.4 0.12 13.1 1.3 4.8 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_10 PF13374.6 CBZ28348.1 - 1.6 8.7 12.5 5.8 6.9 1.7 4.7 4 0 0 4 4 4 0 Tetratricopeptide repeat NINJA_B PF16136.5 CBZ28348.1 - 6.3 7.2 16.9 2.8 8.3 1.7 3.1 4 0 0 4 4 4 0 Putative nuclear localisation signal Dicty_REP PF05086.12 CBZ28348.1 - 7 4.5 4.6 9.7 4.0 4.6 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein DnaJ_C PF01556.18 CBZ28349.1 - 2.7e-32 111.9 0.0 3.6e-32 111.5 0.0 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 CBZ28349.1 - 4.1e-28 97.3 0.7 4.1e-28 97.3 0.7 1.9 2 0 0 2 2 2 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 CBZ28349.1 - 1.4e-13 51.0 16.1 2.3e-13 50.3 16.1 1.4 1 0 0 1 1 1 1 DnaJ central domain Anti-TRAP PF15777.5 CBZ28349.1 - 0.0014 18.5 7.0 0.19 11.7 0.9 2.5 2 0 0 2 2 2 2 Tryptophan RNA-binding attenuator protein inhibitory protein HypA PF01155.19 CBZ28349.1 - 0.25 11.4 7.0 2.8 8.0 0.6 2.6 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DUF5351 PF17302.2 CBZ28349.1 - 2.7 8.3 17.9 1.9 8.8 0.2 4.1 4 0 0 4 4 4 0 Family of unknown function (DUF5351) Aldo_ket_red PF00248.21 CBZ28350.1 - 4.6e-35 121.2 0.0 9.2e-35 120.3 0.0 1.4 1 1 0 1 1 1 1 Aldo/keto reductase family TBPIP PF07106.13 CBZ28351.1 - 1.6e-09 37.6 0.0 2.3e-09 37.1 0.0 1.2 1 0 0 1 1 1 1 TBPIP/Hop2 winged helix domain Nore1-SARAH PF16517.5 CBZ28351.1 - 0.068 13.1 2.3 0.082 12.8 0.4 2.0 2 0 0 2 2 2 0 Novel Ras effector 1 C-terminal SARAH (Sav/Rassf/Hpo) domain adh_short_C2 PF13561.6 CBZ28353.1 - 3.1e-40 138.2 0.4 3.8e-40 137.9 0.4 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 CBZ28353.1 - 1.7e-37 128.8 0.4 2.4e-37 128.3 0.4 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 CBZ28353.1 - 7.3e-14 52.1 1.5 3.2e-13 50.0 1.5 1.8 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 CBZ28353.1 - 1e-05 25.1 0.0 2.2e-05 24.0 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 CBZ28353.1 - 0.059 12.5 0.1 0.11 11.6 0.1 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain NAD_binding_10 PF13460.6 CBZ28353.1 - 0.068 13.1 0.0 0.13 12.2 0.0 1.6 1 0 0 1 1 1 0 NAD(P)H-binding NAD_binding_4 PF07993.12 CBZ28353.1 - 0.098 11.8 0.0 9 5.4 0.0 2.2 2 0 0 2 2 2 0 Male sterility protein AIP3 PF03915.13 CBZ28354.1 - 0.013 14.6 1.5 0.039 13.1 0.4 1.9 2 0 0 2 2 2 0 Actin interacting protein 3 DUF1043 PF06295.12 CBZ28354.1 - 0.082 12.9 2.3 2.7 8.0 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1043) CENP-H PF05837.12 CBZ28354.1 - 0.12 12.7 6.1 4.5 7.7 0.1 2.6 2 0 0 2 2 2 0 Centromere protein H (CENP-H) DUF1039 PF06287.11 CBZ28354.1 - 0.3 11.5 1.2 21 5.7 0.0 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1039) Pkinase PF00069.25 CBZ28355.1 - 1e-48 166.0 0.0 2e-48 165.1 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ28355.1 - 2.2e-22 79.6 0.0 3.9e-22 78.8 0.0 1.3 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CBZ28355.1 - 0.00039 19.8 0.0 0.3 10.4 0.0 2.8 2 1 1 3 3 3 2 Kinase-like APH PF01636.23 CBZ28355.1 - 0.013 15.5 1.7 1.3 8.8 0.2 2.5 1 1 1 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.14 CBZ28355.1 - 0.019 14.3 0.0 0.025 13.9 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.25 CBZ28356.1 - 2.5e-68 230.3 0.0 1.1e-67 228.2 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ28356.1 - 5.3e-32 111.1 0.0 7.6e-32 110.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CBZ28356.1 - 0.00023 20.6 0.0 0.0012 18.2 0.0 2.0 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 CBZ28356.1 - 0.059 13.3 0.1 0.57 10.1 0.0 2.5 2 1 1 3 3 3 0 Phosphotransferase enzyme family Kdo PF06293.14 CBZ28356.1 - 0.062 12.6 0.1 0.29 10.5 0.0 2.0 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 CBZ28356.1 - 0.081 12.5 0.0 5.7 6.5 0.0 2.4 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Prp19 PF08606.11 CBZ28357.1 - 2.4e-24 85.1 0.2 5.1e-24 84.0 0.2 1.5 1 0 0 1 1 1 1 Prp19/Pso4-like WD40 PF00400.32 CBZ28357.1 - 1e-09 38.8 9.1 0.0091 16.8 0.5 5.5 6 0 0 6 6 6 3 WD domain, G-beta repeat zf-Nse PF11789.8 CBZ28357.1 - 0.0011 18.7 0.0 0.0023 17.7 0.0 1.5 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit U-box PF04564.15 CBZ28357.1 - 0.0013 18.9 0.0 0.0025 17.9 0.0 1.5 1 0 0 1 1 1 1 U-box domain Ge1_WD40 PF16529.5 CBZ28357.1 - 0.26 10.2 0.3 2.7 6.9 0.0 2.3 2 0 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein TTL PF03133.15 CBZ28358.1 - 3.8e-48 164.1 0.0 5.4e-48 163.6 0.0 1.1 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 CBZ28358.1 - 5.4e-05 22.6 0.0 0.45 9.7 0.0 3.1 2 1 0 2 2 2 2 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 CBZ28358.1 - 0.0098 15.2 0.0 0.031 13.5 0.0 1.7 2 0 0 2 2 2 1 Sugar-transfer associated ATP-grasp Dala_Dala_lig_C PF07478.13 CBZ28358.1 - 0.026 14.1 0.0 0.044 13.3 0.0 1.3 1 0 0 1 1 1 0 D-ala D-ala ligase C-terminus TFIIF_alpha PF05793.12 CBZ28358.1 - 0.4 9.2 1.4 0.7 8.4 1.4 1.3 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) NPP1 PF05630.11 CBZ28358.1 - 1.8 8.7 3.8 4 7.5 3.8 1.5 1 0 0 1 1 1 0 Necrosis inducing protein (NPP1) Kri1 PF05178.12 CBZ28359.1 - 0.082 13.5 4.6 0.14 12.8 4.6 1.4 1 0 0 1 1 1 0 KRI1-like family AAA_6 PF12774.7 CBZ28360.1 - 4.2e-155 515.7 0.0 2.5e-153 509.8 0.0 3.1 3 0 0 3 3 3 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 CBZ28360.1 - 1.3e-115 386.8 7.0 1.3e-115 386.8 7.0 2.7 3 0 0 3 3 3 1 Dynein heavy chain, N-terminal region 2 Dynein_C PF18199.1 CBZ28360.1 - 1.5e-110 369.3 0.0 4.4e-110 367.7 0.0 1.9 2 0 0 2 2 2 1 Dynein heavy chain C-terminal domain AAA_8 PF12780.7 CBZ28360.1 - 2.9e-93 311.9 0.0 8.6e-93 310.4 0.0 1.9 1 0 0 1 1 1 1 P-loop containing dynein motor region D4 AAA_7 PF12775.7 CBZ28360.1 - 1e-76 256.5 0.0 1.2e-73 246.5 0.0 2.9 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA_9 PF12781.7 CBZ28360.1 - 7.8e-75 250.8 2.5 2e-74 249.5 2.5 1.8 1 0 0 1 1 1 1 ATP-binding dynein motor region AAA_lid_11 PF18198.1 CBZ28360.1 - 2.5e-58 196.5 0.0 7.8e-58 194.9 0.0 2.0 2 0 0 2 2 1 1 Dynein heavy chain AAA lid domain Dynein_heavy PF03028.15 CBZ28360.1 - 4.3e-40 136.5 0.0 1.9e-36 124.8 0.0 3.0 2 0 0 2 2 2 2 Dynein heavy chain region D6 P-loop domain MT PF12777.7 CBZ28360.1 - 2e-23 83.0 11.3 2e-23 83.0 11.3 2.1 3 0 0 3 3 3 1 Microtubule-binding stalk of dynein motor AAA_5 PF07728.14 CBZ28360.1 - 3.6e-19 69.1 0.0 5.2e-05 23.3 0.0 6.1 6 1 1 7 7 5 3 AAA domain (dynein-related subfamily) Dynein_AAA_lid PF17852.1 CBZ28360.1 - 5.4e-19 68.6 0.0 2.1e-18 66.6 0.0 2.2 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain AAA_lid_1 PF17857.1 CBZ28360.1 - 9.7e-14 51.4 0.0 2.8e-13 49.9 0.0 1.8 1 0 0 1 1 1 1 AAA+ lid domain AAA_22 PF13401.6 CBZ28360.1 - 8.3e-09 35.8 2.4 0.013 15.7 0.0 6.2 6 0 0 6 6 5 2 AAA domain AAA PF00004.29 CBZ28360.1 - 1.7e-08 34.9 2.6 0.005 17.3 0.0 3.8 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 CBZ28360.1 - 0.00013 22.5 1.7 0.011 16.2 0.0 4.1 3 0 0 3 3 3 1 AAA domain TsaE PF02367.17 CBZ28360.1 - 0.0034 17.4 0.5 0.5 10.4 0.0 3.5 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE RNA_helicase PF00910.22 CBZ28360.1 - 0.004 17.5 3.2 4.1 7.9 0.0 4.1 4 0 0 4 4 3 1 RNA helicase DUF815 PF05673.13 CBZ28360.1 - 0.0055 15.9 0.1 0.032 13.4 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF815) LBR_tudor PF09465.10 CBZ28360.1 - 0.0093 15.8 0.0 0.68 9.8 0.0 2.6 2 0 0 2 2 2 1 Lamin-B receptor of TUDOR domain AAA_30 PF13604.6 CBZ28360.1 - 0.0097 15.6 10.0 0.19 11.4 0.0 4.1 4 0 0 4 4 3 2 AAA domain AAA_33 PF13671.6 CBZ28360.1 - 0.016 15.4 0.2 4 7.6 0.0 3.9 3 0 0 3 3 2 0 AAA domain MobB PF03205.14 CBZ28360.1 - 0.028 14.3 0.2 0.1 12.5 0.0 2.1 2 0 0 2 2 1 0 Molybdopterin guanine dinucleotide synthesis protein B NACHT PF05729.12 CBZ28360.1 - 0.11 12.4 0.1 1.3 8.9 0.0 2.8 2 0 0 2 2 2 0 NACHT domain T2SSE PF00437.20 CBZ28360.1 - 0.17 10.9 2.8 0.15 11.0 0.0 2.4 2 0 0 2 2 2 0 Type II/IV secretion system protein RBD-FIP PF09457.10 CBZ28360.1 - 0.22 11.5 3.2 1.5 8.8 0.0 3.8 3 0 0 3 3 2 0 FIP domain ABC_tran PF00005.27 CBZ28360.1 - 0.24 11.9 1.4 2.9 8.4 0.0 3.1 2 0 0 2 2 2 0 ABC transporter AAA_16 PF13191.6 CBZ28360.1 - 0.34 11.3 0.0 0.34 11.3 0.0 7.9 10 0 0 10 10 6 0 AAA ATPase domain Mg_chelatase PF01078.21 CBZ28360.1 - 0.55 9.6 2.8 1.5 8.2 0.0 3.0 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI AAA_28 PF13521.6 CBZ28360.1 - 5.3 7.3 10.0 1.4 9.2 0.0 4.4 4 0 0 4 4 3 0 AAA domain HTH_9 PF08221.11 CBZ28361.1 - 3.5e-05 23.8 2.2 0.1 12.7 0.0 3.5 3 0 0 3 3 3 2 RNA polymerase III subunit RPC82 helix-turn-helix domain Methyltransf_31 PF13847.6 CBZ28362.1 - 0.0027 17.5 0.0 0.0049 16.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CBZ28362.1 - 0.044 14.5 0.0 0.11 13.2 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Topo_C_assoc PF14370.6 CBZ28363.1 - 0.18 11.8 0.0 0.28 11.2 0.0 1.3 1 0 0 1 1 1 0 C-terminal topoisomerase domain AAA PF00004.29 CBZ28364.1 - 2.4e-09 37.7 0.0 4.2e-08 33.7 0.0 2.6 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 CBZ28364.1 - 1e-07 32.3 0.1 2.3e-06 27.9 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 CBZ28364.1 - 8.1e-06 26.3 0.0 0.00049 20.5 0.0 2.8 2 2 0 2 2 2 1 AAA ATPase domain T2SSE PF00437.20 CBZ28364.1 - 0.00034 19.8 0.0 0.0015 17.7 0.0 1.9 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_19 PF13245.6 CBZ28364.1 - 0.00099 19.5 0.2 0.0047 17.3 0.2 2.2 1 1 0 1 1 1 1 AAA domain DUF2075 PF09848.9 CBZ28364.1 - 0.0051 16.1 0.0 0.0089 15.3 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) ResIII PF04851.15 CBZ28364.1 - 0.034 14.2 0.0 0.063 13.3 0.0 1.5 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_30 PF13604.6 CBZ28364.1 - 0.041 13.6 0.0 0.11 12.3 0.0 1.8 1 1 0 1 1 1 0 AAA domain AAA_7 PF12775.7 CBZ28364.1 - 0.05 13.1 0.0 0.16 11.5 0.0 1.9 1 1 0 1 1 1 0 P-loop containing dynein motor region NB-ARC PF00931.22 CBZ28364.1 - 0.07 12.3 0.0 0.12 11.6 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain AAA_11 PF13086.6 CBZ28364.1 - 0.073 12.8 0.0 0.16 11.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain ATPase PF06745.13 CBZ28364.1 - 0.078 12.3 0.6 1.5 8.1 0.0 2.3 2 0 0 2 2 2 0 KaiC PPR PF01535.20 CBZ28365.1 - 5e-06 26.4 0.3 0.22 11.8 0.0 6.1 7 0 0 7 7 7 1 PPR repeat PPR_2 PF13041.6 CBZ28365.1 - 0.0018 18.4 1.5 0.25 11.5 0.0 4.9 5 1 1 6 6 6 1 PPR repeat family mRNA_stabil PF13929.6 CBZ28365.1 - 0.041 12.9 1.2 1.7 7.6 0.2 2.6 2 1 1 3 3 3 0 mRNA stabilisation Snurportin1 PF11538.8 CBZ28365.1 - 0.44 10.8 0.1 0.44 10.8 0.1 2.9 3 0 0 3 3 3 0 Snurportin1 NYD-SP28 PF14772.6 CBZ28366.1 - 4.7e-18 65.1 2.9 4.7e-18 65.1 2.9 4.6 2 1 1 4 4 4 1 Sperm tail NYD-SP28_assoc PF14775.6 CBZ28366.1 - 0.00073 19.6 0.3 0.0049 16.9 0.3 2.5 1 0 0 1 1 1 1 Sperm tail C-terminal domain DUF5521 PF17659.1 CBZ28366.1 - 0.0079 14.1 0.0 0.012 13.5 0.0 1.2 1 0 0 1 1 1 1 Family of unknown function (DUF5521) BAG6 PF12057.8 CBZ28366.1 - 0.024 14.3 0.7 0.15 11.8 0.1 2.6 2 1 1 3 3 3 0 BCL2-associated athanogene 6 DUF5069 PF16798.5 CBZ28366.1 - 0.024 14.8 3.0 0.05 13.8 1.9 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF5069) ApoLp-III PF07464.11 CBZ28366.1 - 4.9 7.2 17.6 0.5 10.5 3.0 3.3 1 1 1 2 2 2 0 Apolipophorin-III precursor (apoLp-III) WXG100 PF06013.12 CBZ28366.1 - 6.2 7.1 14.7 0.052 13.8 2.1 3.8 2 1 1 3 3 3 0 Proteins of 100 residues with WXG OmpH PF03938.14 CBZ28366.1 - 7.3 6.9 31.6 6.9 7.0 5.8 3.9 1 1 2 3 3 3 0 Outer membrane protein (OmpH-like) FIST PF08495.10 CBZ28367.1 - 0.00039 20.5 0.6 0.00068 19.7 0.1 1.8 2 0 0 2 2 2 1 FIST N domain Urb2 PF10441.9 CBZ28368.1 - 0.14 12.0 0.1 0.23 11.4 0.1 1.3 1 0 0 1 1 1 0 Urb2/Npa2 family Ank_2 PF12796.7 CBZ28369.1 - 1.2e-09 38.6 0.4 3.7e-05 24.2 0.0 2.9 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 CBZ28369.1 - 4.1e-05 23.6 0.1 0.14 12.8 0.0 3.6 2 0 0 2 2 2 2 Ankyrin repeat IQ PF00612.27 CBZ28369.1 - 5.8e-05 22.5 15.8 0.49 10.3 0.0 5.1 4 0 0 4 4 4 3 IQ calmodulin-binding motif Ank_5 PF13857.6 CBZ28369.1 - 0.0014 18.9 0.5 0.07 13.5 0.0 3.3 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank PF00023.30 CBZ28369.1 - 0.0014 18.9 1.9 0.77 10.3 0.1 4.5 3 0 0 3 3 3 1 Ankyrin repeat Ank_4 PF13637.6 CBZ28369.1 - 0.013 16.1 0.4 0.11 13.1 0.1 2.8 1 1 1 2 2 2 0 Ankyrin repeats (many copies) Guanylate_cyc PF00211.20 CBZ28370.1 - 3.6e-24 85.4 0.0 7.2e-24 84.4 0.0 1.4 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain Globin PF00042.22 CBZ28370.1 - 9.4e-09 35.8 0.2 0.0054 17.3 0.0 2.6 2 0 0 2 2 2 2 Globin Proteasome PF00227.26 CBZ28372.1 - 1e-38 132.7 0.0 1.2e-38 132.6 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit RNA_POL_M_15KD PF02150.16 CBZ28373.1 - 0.00041 20.2 6.5 0.00041 20.2 6.5 2.7 3 0 0 3 3 3 1 RNA polymerases M/15 Kd subunit TFIIS_C PF01096.18 CBZ28373.1 - 0.0027 17.5 3.3 0.0027 17.5 3.3 3.2 3 2 0 3 3 3 1 Transcription factor S-II (TFIIS) zf-Sec23_Sec24 PF04810.15 CBZ28373.1 - 0.018 15.1 3.9 0.018 15.1 3.9 2.0 2 0 0 2 2 2 0 Sec23/Sec24 zinc finger HNH_5 PF14279.6 CBZ28373.1 - 0.035 14.0 4.6 0.23 11.3 0.0 2.8 3 0 0 3 3 3 0 HNH endonuclease Ogr_Delta PF04606.12 CBZ28373.1 - 0.048 13.7 1.6 0.048 13.7 1.6 2.5 2 2 0 2 2 2 0 Ogr/Delta-like zinc finger zf-ribbon_3 PF13248.6 CBZ28373.1 - 0.33 10.4 11.9 3.3 7.3 1.1 4.1 4 0 0 4 4 4 0 zinc-ribbon domain zinc_ribbon_2 PF13240.6 CBZ28373.1 - 6 6.7 14.0 0.3 10.9 0.6 3.3 2 1 0 2 2 2 0 zinc-ribbon domain Lar_restr_allev PF14354.6 CBZ28373.1 - 6.6 7.2 13.6 0.074 13.4 2.2 2.7 2 1 0 2 2 2 0 Restriction alleviation protein Lar Zn_Tnp_IS1595 PF12760.7 CBZ28373.1 - 6.7 6.8 15.8 0.19 11.7 1.6 3.0 2 2 1 3 3 3 0 Transposase zinc-ribbon domain 7tm_1 PF00001.21 CBZ28374.1 - 0.0084 15.5 2.8 0.011 15.1 2.8 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) IBV_3C PF03620.13 CBZ28374.1 - 6.7 7.3 6.4 2.5 8.7 3.0 2.0 2 1 0 2 2 2 0 IBV 3C protein Fumble PF03630.14 CBZ28375.1 - 2.4e-95 319.5 0.0 3.7e-95 318.9 0.0 1.3 1 0 0 1 1 1 1 Fumble AMP-binding PF00501.28 CBZ28375.1 - 4.3e-15 55.2 0.1 1.8e-09 36.7 0.0 2.2 2 0 0 2 2 2 2 AMP-binding enzyme Exo_endo_phos PF03372.23 CBZ28375.1 - 1.1e-08 34.9 0.0 1.8e-08 34.2 0.0 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family MFS_1 PF07690.16 CBZ28376.1 - 6.7e-34 117.3 61.0 2.4e-27 95.8 36.7 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 CBZ28376.1 - 0.11 11.3 34.2 4.6 6.0 34.1 3.1 1 1 0 1 1 1 0 Sugar (and other) transporter Spo7_2_N PF15407.6 CBZ28377.1 - 0.029 14.0 0.0 0.07 12.8 0.0 1.6 1 0 0 1 1 1 0 Sporulation protein family 7 RRM_1 PF00076.22 CBZ28377.1 - 0.035 13.9 0.0 0.19 11.6 0.0 2.1 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF5316 PF17247.2 CBZ28377.1 - 0.048 13.7 0.0 1.1 9.3 0.0 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5316) RRM_occluded PF16842.5 CBZ28377.1 - 0.099 12.5 0.0 0.24 11.3 0.0 1.7 1 1 0 1 1 1 0 Occluded RNA-recognition motif DSPc PF00782.20 CBZ28378.1 - 1.2e-26 93.0 0.0 1.8e-26 92.5 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain LRR_8 PF13855.6 CBZ28378.1 - 2.7e-08 33.4 12.7 0.00011 21.9 4.3 3.7 3 0 0 3 3 3 3 Leucine rich repeat LRR_4 PF12799.7 CBZ28378.1 - 1.7e-05 25.1 13.9 0.0039 17.6 6.9 3.7 2 1 1 3 3 3 3 Leucine Rich repeats (2 copies) Y_phosphatase PF00102.27 CBZ28378.1 - 0.0028 17.3 0.0 0.0044 16.6 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase LRR_9 PF14580.6 CBZ28378.1 - 0.095 12.2 4.0 3.9 6.9 1.0 2.3 2 0 0 2 2 2 0 Leucine-rich repeat CDKN3 PF05706.12 CBZ28378.1 - 0.1 12.3 0.0 0.18 11.5 0.0 1.3 1 0 0 1 1 1 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) Histone PF00125.24 CBZ28382.1 - 1.2e-11 45.1 0.0 1.5e-11 44.8 0.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 CBZ28382.1 - 0.012 15.8 0.3 0.023 15.0 0.3 1.4 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone DHHC PF01529.20 CBZ28383.1 - 1.3e-30 106.2 2.4 1.3e-30 106.2 2.4 2.2 2 1 0 2 2 2 1 DHHC palmitoyltransferase BNIP3 PF06553.12 CBZ28384.1 - 0.013 15.2 0.5 0.02 14.6 0.5 1.3 1 0 0 1 1 1 0 BNIP3 DAO PF01266.24 CBZ28385.1 - 4.7e-42 144.8 0.0 8.7e-42 144.0 0.0 1.4 1 1 0 1 1 1 1 FAD dependent oxidoreductase DAO_C PF16901.5 CBZ28385.1 - 7.6e-31 106.6 0.0 1.5e-30 105.7 0.0 1.5 1 0 0 1 1 1 1 C-terminal domain of alpha-glycerophosphate oxidase Pyr_redox_2 PF07992.14 CBZ28385.1 - 0.0057 15.9 0.1 0.055 12.7 0.1 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 CBZ28385.1 - 0.025 13.7 1.4 0.048 12.7 1.4 1.4 1 0 0 1 1 1 0 FAD binding domain FAD_oxidored PF12831.7 CBZ28385.1 - 0.03 13.7 1.4 0.05 12.9 1.4 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase 3HCDH_N PF02737.18 CBZ28385.1 - 0.046 13.6 0.2 0.095 12.6 0.2 1.6 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain HI0933_like PF03486.14 CBZ28385.1 - 0.36 9.5 2.3 0.28 9.8 0.8 1.5 2 0 0 2 2 2 0 HI0933-like protein NAD_binding_8 PF13450.6 CBZ28385.1 - 0.44 10.8 1.6 2 8.7 1.7 2.1 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 CBZ28385.1 - 0.71 10.5 2.5 2 9.0 0.9 2.6 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 CBZ28385.1 - 4.8 6.4 6.4 0.44 9.8 0.0 2.5 4 0 0 4 4 4 0 Alanine dehydrogenase/PNT, C-terminal domain NADH-u_ox-rdase PF10785.9 CBZ28386.1 - 7.5e-11 42.6 1.0 1.7e-10 41.4 1.0 1.6 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit LRR_RI_capping PF18779.1 CBZ28387.1 - 5 6.9 8.8 5.4 6.7 0.0 4.1 5 0 0 5 5 5 0 Capping Ribonuclease inhibitor Leucine Rich Repeat PAPS_reduct PF01507.19 CBZ28388.1 - 2.6e-23 83.0 0.0 3.1e-17 63.2 0.0 2.1 1 1 1 2 2 2 2 Phosphoadenosine phosphosulfate reductase family ATP_bind_3 PF01171.20 CBZ28388.1 - 0.0055 16.5 0.0 0.007 16.1 0.0 1.2 1 0 0 1 1 1 1 PP-loop family FPV060 PF17614.2 CBZ28390.1 - 0.19 11.1 0.2 0.26 10.6 0.2 1.1 1 0 0 1 1 1 0 Viral CC-type chemokine zf_CCCH_4 PF18345.1 CBZ28391.1 - 6.8e-07 29.1 12.0 0.0013 18.7 3.8 2.7 2 0 0 2 2 2 2 Zinc finger domain zf-HIT PF04438.16 CBZ28391.1 - 7.3e-05 22.6 11.1 7.3e-05 22.6 11.1 2.0 2 0 0 2 2 2 1 HIT zinc finger zf-CCCH PF00642.24 CBZ28391.1 - 0.00018 21.3 1.2 0.00018 21.3 1.2 3.4 3 0 0 3 3 3 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Torus PF16131.5 CBZ28391.1 - 0.0015 19.2 5.3 0.084 13.6 0.3 2.7 1 1 1 2 2 2 2 Torus domain U71 PF17474.2 CBZ28391.1 - 0.075 13.0 0.0 0.21 11.5 0.0 1.8 1 0 0 1 1 1 0 Tegument protein UL11 homolog zf-CCCH_2 PF14608.6 CBZ28391.1 - 0.27 11.8 10.3 1.2 9.7 2.8 2.8 2 0 0 2 2 2 0 RNA-binding, Nab2-type zinc finger zf-CCCH_3 PF15663.5 CBZ28391.1 - 2.2 8.6 10.8 0.51 10.6 0.4 3.3 2 1 1 3 3 3 0 Zinc-finger containing family RNB PF00773.19 CBZ28394.1 - 2.1e-95 319.8 0.0 3.8e-95 319.0 0.0 1.4 1 0 0 1 1 1 1 RNB domain OB_Dis3 PF17849.1 CBZ28394.1 - 2.2e-20 72.4 0.0 4.6e-20 71.4 0.0 1.6 1 0 0 1 1 1 1 Dis3-like cold-shock domain 2 (CSD2) Rrp44_CSD1 PF17216.3 CBZ28394.1 - 6.9e-08 32.3 0.0 1.6e-07 31.1 0.0 1.6 1 0 0 1 1 1 1 Rrp44-like cold shock domain CSD2 PF17876.1 CBZ28394.1 - 5.9e-06 26.4 0.0 5e-05 23.4 0.0 2.4 2 0 0 2 2 2 1 Cold shock domain Rrp44_S1 PF17215.3 CBZ28394.1 - 0.00077 19.4 0.1 0.0029 17.5 0.1 2.0 1 1 0 1 1 1 1 S1 domain Dis3l2_C_term PF17877.1 CBZ28394.1 - 0.013 15.8 0.0 0.035 14.4 0.0 1.6 1 0 0 1 1 1 0 DIS3-like exonuclease 2 C terminal MtN3_slv PF03083.16 CBZ28396.1 - 4.9e-19 68.2 10.9 6.5e-11 42.1 2.6 2.4 2 0 0 2 2 2 2 Sugar efflux transporter for intercellular exchange Tox-ODYAM1 PF15642.6 CBZ28396.1 - 0.016 14.2 0.1 0.022 13.8 0.1 1.1 1 0 0 1 1 1 0 Toxin in Odyssella and Amoebophilus TMEM208_SND2 PF05620.11 CBZ28396.1 - 0.59 9.9 5.8 3.3 7.5 0.2 2.6 3 0 0 3 3 3 0 SRP-independent targeting protein 2/TMEM208 ThiF PF00899.21 CBZ28397.1 - 1.4e-10 40.9 0.2 2.5e-10 40.1 0.2 1.4 1 0 0 1 1 1 1 ThiF family Nab1 PF04902.12 CBZ28397.1 - 0.11 12.8 0.6 0.17 12.3 0.6 1.2 1 0 0 1 1 1 0 Conserved region in Nab1 Sacchrp_dh_NADP PF03435.18 CBZ28399.1 - 2.7e-22 79.4 0.2 5.3e-22 78.5 0.2 1.5 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain NAD_binding_10 PF13460.6 CBZ28399.1 - 0.00045 20.2 0.0 0.0022 17.9 0.1 2.1 2 1 0 2 2 2 1 NAD(P)H-binding Epimerase PF01370.21 CBZ28399.1 - 0.011 15.2 0.0 0.018 14.5 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 CBZ28399.1 - 0.05 12.6 0.0 0.075 12.0 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Semialdhyde_dh PF01118.24 CBZ28399.1 - 0.094 13.2 0.0 0.22 12.0 0.0 1.6 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain AAA PF00004.29 CBZ28401.1 - 1.3e-39 135.7 0.0 2.8e-39 134.5 0.0 1.6 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 CBZ28401.1 - 2.2e-10 40.2 0.0 7.6e-10 38.4 0.0 2.0 1 1 0 1 1 1 1 AAA+ lid domain Vps4_C PF09336.10 CBZ28401.1 - 2.1e-08 34.0 0.5 6.9e-08 32.4 0.3 1.9 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain RuvB_N PF05496.12 CBZ28401.1 - 1.4e-05 24.9 0.0 3e-05 23.8 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 CBZ28401.1 - 0.0002 21.4 0.0 0.0019 18.2 0.0 2.5 3 1 0 3 3 3 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 CBZ28401.1 - 0.00096 19.6 0.0 0.0021 18.5 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain Mg_chelatase PF01078.21 CBZ28401.1 - 0.001 18.5 0.1 0.0023 17.4 0.1 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_22 PF13401.6 CBZ28401.1 - 0.0014 18.9 0.1 0.021 15.1 0.1 2.4 1 1 0 1 1 1 1 AAA domain AAA_24 PF13479.6 CBZ28401.1 - 0.0032 17.2 0.0 0.0072 16.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.6 CBZ28401.1 - 0.0048 16.9 0.0 0.012 15.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 CBZ28401.1 - 0.0065 16.6 0.0 0.014 15.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.6 CBZ28401.1 - 0.0066 16.0 0.2 0.31 10.6 0.1 2.6 1 1 1 2 2 2 1 AAA domain NACHT PF05729.12 CBZ28401.1 - 0.007 16.3 0.1 0.14 12.1 0.0 2.6 3 0 0 3 3 2 1 NACHT domain ATPase PF06745.13 CBZ28401.1 - 0.0082 15.5 0.1 2.4 7.5 0.0 2.7 2 1 1 3 3 3 1 KaiC TIP49 PF06068.13 CBZ28401.1 - 0.0087 15.3 0.0 0.017 14.3 0.0 1.5 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_2 PF07724.14 CBZ28401.1 - 0.01 16.0 0.0 0.032 14.3 0.0 1.9 2 0 0 2 2 2 0 AAA domain (Cdc48 subfamily) IstB_IS21 PF01695.17 CBZ28401.1 - 0.013 15.2 0.0 0.036 13.8 0.0 1.7 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_7 PF12775.7 CBZ28401.1 - 0.019 14.5 0.0 0.044 13.3 0.0 1.6 1 0 0 1 1 1 0 P-loop containing dynein motor region RNA_helicase PF00910.22 CBZ28401.1 - 0.021 15.2 0.0 0.058 13.8 0.0 1.8 1 0 0 1 1 1 0 RNA helicase AAA_18 PF13238.6 CBZ28401.1 - 0.031 14.8 1.8 0.037 14.6 0.0 2.1 3 0 0 3 3 1 0 AAA domain DUF815 PF05673.13 CBZ28401.1 - 0.072 12.2 0.0 0.35 10.0 0.0 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF815) Parvo_NS1 PF01057.17 CBZ28401.1 - 0.085 11.9 0.0 0.19 10.8 0.0 1.5 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 PhoH PF02562.16 CBZ28401.1 - 0.11 12.0 0.0 0.21 11.0 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein Sigma54_activat PF00158.26 CBZ28401.1 - 0.14 11.8 0.0 0.59 9.8 0.0 2.0 2 0 0 2 2 2 0 Sigma-54 interaction domain TsaE PF02367.17 CBZ28401.1 - 0.15 12.1 0.0 0.28 11.2 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_28 PF13521.6 CBZ28401.1 - 0.16 12.2 0.0 0.4 10.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.6 CBZ28401.1 - 0.17 12.3 0.3 0.81 10.1 0.0 2.2 2 0 0 2 2 2 0 AAA domain Carn_acyltransf PF00755.20 CBZ28405.1 - 0.00019 20.3 0.0 0.00029 19.6 0.0 1.2 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase RNB PF00773.19 CBZ28406.1 - 1e-90 304.4 0.0 1.5e-90 303.8 0.0 1.3 1 0 0 1 1 1 1 RNB domain Varsurf_PPLC PF03490.13 CBZ28407.1 - 0.13 12.2 0.3 0.92 9.5 0.0 2.3 2 0 0 2 2 2 0 Variant-surface-glycoprotein phospholipase C WD40 PF00400.32 CBZ28408.1 - 0.03 15.2 0.5 9.2 7.3 0.1 3.9 3 1 0 3 3 3 0 WD domain, G-beta repeat Carb_anhydrase PF00194.21 CBZ28409.1 - 3e-28 99.1 0.0 4.1e-28 98.6 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic-type carbonic anhydrase DUF1275 PF06912.11 CBZ28409.1 - 0.029 14.3 0.3 0.075 13.0 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1275) SOG2 PF10428.9 CBZ28409.1 - 1.2 8.2 13.0 1.8 7.7 13.0 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein AJAP1_PANP_C PF15298.6 CBZ28410.1 - 0.025 14.8 2.9 0.025 14.8 2.0 1.5 1 1 0 1 1 1 0 AJAP1/PANP C-terminus Carboxyl_trans PF01039.22 CBZ28411.1 - 5.9e-174 579.3 0.0 6.7e-174 579.1 0.0 1.0 1 0 0 1 1 1 1 Carboxyl transferase domain MdcE PF06833.11 CBZ28411.1 - 0.0012 18.3 0.1 0.0032 17.0 0.0 1.7 2 0 0 2 2 2 1 Malonate decarboxylase gamma subunit (MdcE) ACCA PF03255.14 CBZ28411.1 - 0.15 11.9 0.8 1.9 8.3 0.0 2.4 2 1 0 2 2 2 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit TPR_2 PF07719.17 CBZ28412.1 - 7.1e-06 25.7 2.7 2.4 8.5 0.2 3.8 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_16 PF13432.6 CBZ28412.1 - 2.1e-05 25.1 0.5 0.011 16.4 0.2 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.28 CBZ28412.1 - 4.8e-05 23.0 3.6 1.1 9.2 0.0 3.8 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_12 PF13424.6 CBZ28412.1 - 0.00075 19.7 0.8 0.45 10.8 0.4 3.2 2 1 0 2 2 2 2 Tetratricopeptide repeat CheD PF03975.13 CBZ28412.1 - 0.085 13.0 0.0 0.37 10.9 0.0 2.0 2 0 0 2 2 2 0 CheD chemotactic sensory transduction zf-MYND PF01753.18 CBZ28412.1 - 0.18 12.0 14.9 0.54 10.4 14.9 1.9 1 1 0 1 1 1 0 MYND finger DUF2800 PF10926.8 CBZ28413.1 - 0.13 11.5 0.3 1.5 8.0 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2800) Pkinase PF00069.25 CBZ28414.1 - 7.4e-63 212.4 0.0 8.5e-63 212.2 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ28414.1 - 1.5e-39 135.8 0.0 1.8e-39 135.6 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CBZ28414.1 - 1.4e-06 27.9 0.0 1.9e-06 27.4 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 CBZ28414.1 - 8.3e-05 21.7 0.1 0.00012 21.2 0.1 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Pkinase_fungal PF17667.1 CBZ28414.1 - 0.0042 15.9 0.0 0.0062 15.4 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase FTA2 PF13095.6 CBZ28414.1 - 0.0045 16.6 0.1 0.71 9.5 0.0 2.2 2 0 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 CBZ28414.1 - 0.0047 16.9 1.7 0.022 14.7 0.9 2.0 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 CBZ28414.1 - 0.006 16.0 0.1 0.012 14.9 0.1 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.11 CBZ28414.1 - 0.023 13.7 0.0 0.04 13.0 0.0 1.4 1 0 0 1 1 1 0 Seadornavirus VP7 YrbL-PhoP_reg PF10707.9 CBZ28414.1 - 0.042 13.4 0.0 0.079 12.5 0.0 1.4 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL GP52 PF17468.2 CBZ28414.1 - 0.13 12.4 0.0 0.43 10.8 0.0 1.9 1 0 0 1 1 1 0 Phage gene product 52 AAA_23 PF13476.6 CBZ28415.1 - 1.4e-27 97.6 0.0 1.4e-27 97.6 0.0 6.7 2 2 0 3 3 1 1 AAA domain SMC_N PF02463.19 CBZ28415.1 - 1.1e-14 54.5 0.0 5.6e-07 29.2 0.0 2.8 2 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_15 PF13175.6 CBZ28415.1 - 3.5e-09 36.9 12.5 2.6e-05 24.1 1.9 3.0 3 0 0 3 3 3 2 AAA ATPase domain SbcCD_C PF13558.6 CBZ28415.1 - 4.2e-08 33.3 0.3 4.1e-07 30.1 0.0 2.8 2 0 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_21 PF13304.6 CBZ28415.1 - 4.3e-08 33.3 0.0 0.001 18.9 0.1 2.5 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 CBZ28415.1 - 0.0016 18.1 0.0 0.004 16.9 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain ABC_tran PF00005.27 CBZ28415.1 - 0.0036 17.8 0.0 0.0036 17.8 0.0 6.3 4 2 0 4 4 3 2 ABC transporter Rad50_zn_hook PF04423.14 CBZ28415.1 - 0.09 12.6 0.2 0.09 12.6 0.2 3.8 3 0 0 3 3 3 0 Rad50 zinc hook motif DUF2256 PF10013.9 CBZ28415.1 - 0.17 12.0 0.1 0.56 10.4 0.1 1.8 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2256) RsgA_GTPase PF03193.16 CBZ28415.1 - 0.47 10.3 0.0 0.47 10.3 0.0 3.6 4 0 0 4 4 3 0 RsgA GTPase Pox_A_type_inc PF04508.12 CBZ28415.1 - 0.48 10.4 5.5 11 6.1 0.1 4.7 4 0 0 4 4 4 0 Viral A-type inclusion protein repeat ATP-cone PF03477.16 CBZ28415.1 - 2.8 8.6 7.4 1.4 9.6 0.3 4.2 3 0 0 3 3 3 0 ATP cone domain AAA_18 PF13238.6 CBZ28415.1 - 7.7 7.1 8.6 2.3 8.8 0.1 3.9 2 1 1 3 3 3 0 AAA domain DAGK_cat PF00781.24 CBZ28415.1 - 8 6.1 7.7 2.2 7.9 0.1 3.9 3 0 0 3 3 3 0 Diacylglycerol kinase catalytic domain Ribosomal_S26e PF01283.19 CBZ28416.1 - 1.1e-35 122.4 4.4 1.1e-35 122.3 4.4 1.0 1 0 0 1 1 1 1 Ribosomal protein S26e Rad51 PF08423.11 CBZ28417.1 - 6e-129 428.8 0.4 9.9e-129 428.0 0.2 1.4 2 0 0 2 2 2 1 Rad51 AAA_25 PF13481.6 CBZ28417.1 - 7.9e-11 41.9 0.1 1.3e-10 41.2 0.1 1.2 1 0 0 1 1 1 1 AAA domain RecA PF00154.21 CBZ28417.1 - 1.8e-10 40.8 0.2 3e-10 40.0 0.2 1.3 1 0 0 1 1 1 1 recA bacterial DNA recombination protein HHH_5 PF14520.6 CBZ28417.1 - 8e-05 23.2 0.1 0.00024 21.6 0.1 1.8 1 0 0 1 1 1 1 Helix-hairpin-helix domain ATPase PF06745.13 CBZ28417.1 - 0.00013 21.4 0.6 0.00052 19.4 0.6 1.9 1 1 0 1 1 1 1 KaiC DnaB_C PF03796.15 CBZ28417.1 - 0.0021 17.4 0.1 0.011 15.1 0.0 2.0 2 0 0 2 2 2 1 DnaB-like helicase C terminal domain AAA_22 PF13401.6 CBZ28417.1 - 0.032 14.5 0.3 0.1 12.9 0.1 1.9 2 1 0 2 2 2 0 AAA domain PAXNEB PF05625.11 CBZ28417.1 - 0.74 8.9 0.0 0.74 8.9 0.0 2.1 3 0 0 3 3 3 0 PAXNEB protein Mod_r PF07200.13 CBZ28418.1 - 2.8e-10 40.5 4.7 5.1e-10 39.6 4.7 1.4 1 0 0 1 1 1 1 Modifier of rudimentary (Mod(r)) protein JMY PF15871.5 CBZ28418.1 - 0.00027 20.4 0.9 0.00041 19.8 0.9 1.2 1 0 0 1 1 1 1 Junction-mediating and -regulatory protein TMCO5 PF14992.6 CBZ28418.1 - 0.004 16.8 2.3 0.0054 16.4 2.3 1.2 1 0 0 1 1 1 1 TMCO5 family ADIP PF11559.8 CBZ28418.1 - 0.005 16.9 4.4 0.012 15.7 4.4 1.6 1 0 0 1 1 1 1 Afadin- and alpha -actinin-Binding Tropomyosin_1 PF12718.7 CBZ28418.1 - 0.0055 16.9 2.2 0.013 15.7 2.2 1.6 1 0 0 1 1 1 1 Tropomyosin like Uso1_p115_C PF04871.13 CBZ28418.1 - 0.0057 17.0 2.7 0.013 15.9 2.7 1.6 1 0 0 1 1 1 1 Uso1 / p115 like vesicle tethering protein, C terminal region Phage_GP20 PF06810.11 CBZ28418.1 - 0.011 15.6 1.4 0.019 14.8 0.6 1.8 2 0 0 2 2 2 0 Phage minor structural protein GP20 APG6_N PF17675.1 CBZ28418.1 - 0.012 16.2 3.2 0.012 16.2 3.2 1.8 2 0 0 2 2 1 0 Apg6 coiled-coil region Csm1_N PF18504.1 CBZ28418.1 - 0.014 15.7 7.2 0.014 15.7 7.2 2.1 2 0 0 2 2 2 0 Csm1 N-terminal domain End3 PF12761.7 CBZ28418.1 - 0.017 15.3 4.8 0.032 14.4 4.8 1.4 1 0 0 1 1 1 0 Actin cytoskeleton-regulatory complex protein END3 DUF4162 PF13732.6 CBZ28418.1 - 0.024 15.3 0.3 7.6 7.3 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4162) YscO PF07321.12 CBZ28418.1 - 0.029 14.3 5.5 0.079 12.9 5.5 1.7 1 0 0 1 1 1 0 Type III secretion protein YscO Adenylate_cycl PF01295.18 CBZ28418.1 - 0.033 12.8 0.1 0.043 12.5 0.1 1.2 1 0 0 1 1 1 0 Adenylate cyclase, class-I Cnn_1N PF07989.11 CBZ28418.1 - 0.042 14.0 4.5 0.061 13.5 3.2 1.9 1 1 1 2 2 2 0 Centrosomin N-terminal motif 1 Spc24 PF08286.11 CBZ28418.1 - 0.049 13.9 3.7 0.091 13.0 1.9 2.2 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 DUF1280 PF06918.14 CBZ28418.1 - 0.058 13.0 0.3 0.08 12.5 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1280) TSC22 PF01166.18 CBZ28418.1 - 0.07 13.5 4.1 0.2 12.0 3.6 2.2 1 1 0 1 1 1 0 TSC-22/dip/bun family GAS PF13851.6 CBZ28418.1 - 0.092 12.1 7.6 0.18 11.1 7.6 1.5 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding DivIC PF04977.15 CBZ28418.1 - 0.11 12.3 5.2 0.093 12.5 2.8 2.1 1 1 1 2 2 2 0 Septum formation initiator CENP-H PF05837.12 CBZ28418.1 - 0.12 12.8 4.4 0.26 11.7 4.4 1.6 1 0 0 1 1 1 0 Centromere protein H (CENP-H) COG2 PF06148.11 CBZ28418.1 - 0.15 12.2 5.1 0.055 13.6 2.4 1.7 2 0 0 2 2 1 0 COG (conserved oligomeric Golgi) complex component, COG2 bZIP_1 PF00170.21 CBZ28418.1 - 0.15 12.2 2.5 0.21 11.7 0.5 2.1 1 1 2 3 3 3 0 bZIP transcription factor DUF16 PF01519.16 CBZ28418.1 - 0.15 12.5 2.5 0.44 11.1 2.5 1.8 1 0 0 1 1 1 0 Protein of unknown function DUF16 ZapB PF06005.12 CBZ28418.1 - 0.15 12.5 8.0 0.37 11.3 8.0 1.6 1 0 0 1 1 1 0 Cell division protein ZapB Tup_N PF08581.10 CBZ28418.1 - 0.16 12.3 5.2 0.36 11.1 4.4 2.0 2 0 0 2 2 1 0 Tup N-terminal JAKMIP_CC3 PF16034.5 CBZ28418.1 - 0.21 11.5 9.2 0.65 9.9 9.0 1.9 1 1 1 2 2 2 0 JAKMIP CC3 domain FlaC_arch PF05377.11 CBZ28418.1 - 0.24 11.8 9.0 0.25 11.8 2.4 3.2 2 1 0 3 3 3 0 Flagella accessory protein C (FlaC) NPV_P10 PF05531.12 CBZ28418.1 - 0.4 11.2 9.4 0.62 10.6 5.9 2.7 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein FAM184 PF15665.5 CBZ28418.1 - 0.47 10.2 8.3 0.42 10.4 6.0 2.1 2 1 0 2 2 2 0 Family with sequence similarity 184, A and B Fib_alpha PF08702.10 CBZ28418.1 - 0.62 10.3 10.8 1.2 9.3 5.1 2.7 3 1 0 3 3 2 0 Fibrinogen alpha/beta chain family PI3K_P85_iSH2 PF16454.5 CBZ28418.1 - 0.67 9.5 7.4 0.9 9.1 5.7 1.9 1 1 1 2 2 2 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain DUF641 PF04859.12 CBZ28418.1 - 1.4 9.3 6.1 1.2 9.5 3.8 2.0 2 1 1 3 3 2 0 Plant protein of unknown function (DUF641) bZIP_2 PF07716.15 CBZ28418.1 - 2.4 8.3 7.9 0.37 10.9 1.4 2.7 2 1 1 3 3 2 0 Basic region leucine zipper Peptidase_M8 PF01457.16 CBZ28419.1 - 3.6e-141 471.4 1.1 4.5e-141 471.1 1.1 1.0 1 0 0 1 1 1 1 Leishmanolysin Peptidase_M10 PF00413.24 CBZ28419.1 - 0.0094 15.8 0.0 0.014 15.3 0.0 1.3 1 0 0 1 1 1 1 Matrixin Astacin PF01400.24 CBZ28419.1 - 0.02 14.5 0.2 0.051 13.2 0.0 1.7 2 0 0 2 2 2 0 Astacin (Peptidase family M12A) Pkinase PF00069.25 CBZ28420.1 - 6.6e-54 183.0 0.0 5.5e-36 124.3 0.0 2.4 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ28420.1 - 9.7e-22 77.5 0.0 1.2e-19 70.7 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.23 CBZ28420.1 - 0.012 15.5 1.6 0.028 14.4 0.2 2.2 2 1 1 3 3 3 0 Phosphotransferase enzyme family Kdo PF06293.14 CBZ28420.1 - 0.057 12.8 0.0 0.094 12.1 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 CBZ28420.1 - 0.099 12.3 0.1 5.3 6.6 0.0 2.2 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Haspin_kinase PF12330.8 CBZ28420.1 - 0.11 11.4 0.0 0.39 9.6 0.0 1.8 1 1 0 1 1 1 0 Haspin like kinase domain SlyX PF04102.12 CBZ28421.1 - 0.01 16.5 10.8 1.4 9.6 4.3 3.3 3 0 0 3 3 3 2 SlyX DUF812 PF05667.11 CBZ28421.1 - 0.012 14.5 1.8 0.012 14.5 0.3 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF812) Med9 PF07544.13 CBZ28421.1 - 0.022 14.8 1.6 3.8 7.7 1.1 2.9 2 0 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 DUF4618 PF15397.6 CBZ28421.1 - 0.05 13.0 2.3 0.24 10.8 0.5 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4618) Phage_GP20 PF06810.11 CBZ28421.1 - 0.12 12.2 0.6 0.41 10.4 0.1 2.0 2 0 0 2 2 2 0 Phage minor structural protein GP20 USP8_interact PF08941.10 CBZ28421.1 - 0.14 11.9 1.0 0.54 10.0 0.4 2.2 2 0 0 2 2 2 0 USP8 interacting Spc29 PF17082.5 CBZ28421.1 - 0.21 11.4 1.3 0.68 9.7 1.0 1.8 1 1 0 1 1 1 0 Spindle Pole Component 29 NPV_P10 PF05531.12 CBZ28421.1 - 0.38 11.3 2.4 9.5 6.8 0.7 2.6 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Retrotrans_gag PF03732.17 CBZ28421.1 - 0.38 11.0 2.4 32 4.9 0.6 2.8 3 0 0 3 3 2 0 Retrotransposon gag protein Spc7 PF08317.11 CBZ28421.1 - 0.56 9.0 4.7 7.8 5.3 1.8 2.6 3 0 0 3 3 3 0 Spc7 kinetochore protein APG6_N PF17675.1 CBZ28421.1 - 1.3 9.5 7.3 2 8.9 5.0 2.4 2 1 0 2 2 1 0 Apg6 coiled-coil region KxDL PF10241.9 CBZ28421.1 - 5.8 7.3 7.1 1.8 8.9 3.8 1.9 2 0 0 2 2 1 0 Uncharacterized conserved protein ZapB PF06005.12 CBZ28421.1 - 7.4 7.1 8.7 43 4.7 3.2 2.9 3 0 0 3 3 3 0 Cell division protein ZapB Csm1_N PF18504.1 CBZ28421.1 - 9.1 6.7 6.8 33 4.9 0.1 2.6 2 0 0 2 2 2 0 Csm1 N-terminal domain DMAP1 PF05499.12 CBZ28422.1 - 0.9 9.4 8.1 1 9.2 8.1 1.0 1 0 0 1 1 1 0 DNA methyltransferase 1-associated protein 1 (DMAP1) AAA_6 PF12774.7 CBZ28423.1 - 4.6e-151 502.4 0.0 4.8e-149 495.7 0.0 3.1 3 0 0 3 3 3 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 CBZ28423.1 - 1.4e-118 396.5 1.7 1.4e-118 396.5 1.7 2.8 3 0 0 3 3 3 1 Dynein heavy chain, N-terminal region 2 Dynein_C PF18199.1 CBZ28423.1 - 3e-104 348.5 0.0 1.6e-103 346.2 0.0 2.3 2 0 0 2 2 2 1 Dynein heavy chain C-terminal domain AAA_8 PF12780.7 CBZ28423.1 - 3.7e-93 311.6 0.0 9.2e-90 300.5 0.0 3.7 3 0 0 3 3 3 1 P-loop containing dynein motor region D4 AAA_9 PF12781.7 CBZ28423.1 - 1.5e-78 263.0 2.7 1.5e-78 263.0 2.7 2.7 4 0 0 4 4 4 1 ATP-binding dynein motor region AAA_7 PF12775.7 CBZ28423.1 - 3e-64 215.8 0.0 2.9e-59 199.6 0.0 3.9 3 0 0 3 3 3 2 P-loop containing dynein motor region AAA_lid_11 PF18198.1 CBZ28423.1 - 5.4e-55 185.7 0.0 2.1e-54 183.8 0.0 2.1 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain MT PF12777.7 CBZ28423.1 - 2.9e-46 158.1 4.1 2.9e-46 158.1 4.1 2.0 2 0 0 2 2 2 1 Microtubule-binding stalk of dynein motor Dynein_heavy PF03028.15 CBZ28423.1 - 3.6e-45 152.9 0.9 5.7e-44 149.0 0.1 3.2 3 0 0 3 3 3 1 Dynein heavy chain region D6 P-loop domain Dynein_AAA_lid PF17852.1 CBZ28423.1 - 2.2e-17 63.4 0.0 1.1e-16 61.0 0.0 2.3 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain AAA_lid_1 PF17857.1 CBZ28423.1 - 1.8e-16 60.2 0.2 5.7e-16 58.6 0.2 1.9 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 CBZ28423.1 - 3.1e-15 56.4 0.1 0.00036 20.5 0.0 6.4 5 2 0 5 5 5 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 CBZ28423.1 - 9.9e-08 32.3 1.3 1.4 9.2 0.0 5.3 4 0 0 4 4 4 2 AAA domain RNA_helicase PF00910.22 CBZ28423.1 - 1.5e-06 28.6 0.0 0.026 14.9 0.0 4.3 4 0 0 4 4 4 1 RNA helicase AAA_16 PF13191.6 CBZ28423.1 - 5.3e-06 26.9 1.4 0.56 10.6 0.0 6.0 4 2 1 6 6 6 2 AAA ATPase domain AAA PF00004.29 CBZ28423.1 - 1.3e-05 25.7 0.2 1.3 9.4 0.0 5.0 5 0 0 5 5 5 1 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 CBZ28423.1 - 4.6e-05 24.0 0.0 0.24 12.0 0.0 4.2 3 0 0 3 3 2 1 AAA domain T2SSE PF00437.20 CBZ28423.1 - 0.00062 18.9 1.3 0.2 10.7 0.0 4.3 6 0 0 6 6 6 1 Type II/IV secretion system protein AAA_30 PF13604.6 CBZ28423.1 - 0.0011 18.8 9.4 1.4 8.6 0.0 4.2 4 0 0 4 4 3 3 AAA domain Baculo_PEP_C PF04513.12 CBZ28423.1 - 0.0022 18.0 4.5 3.4 7.7 0.1 5.2 5 0 0 5 5 4 1 Baculovirus polyhedron envelope protein, PEP, C terminus AAA_24 PF13479.6 CBZ28423.1 - 0.0091 15.7 0.2 1.8 8.2 0.0 3.4 3 0 0 3 3 3 1 AAA domain Mg_chelatase PF01078.21 CBZ28423.1 - 0.023 14.1 3.6 0.79 9.1 0.0 4.2 5 0 0 5 5 5 0 Magnesium chelatase, subunit ChlI PhoH PF02562.16 CBZ28423.1 - 0.095 12.1 3.9 3.4 7.1 0.0 3.4 3 0 0 3 3 3 0 PhoH-like protein AAA_25 PF13481.6 CBZ28423.1 - 0.11 12.1 1.4 20 4.7 0.0 4.2 4 0 0 4 4 3 0 AAA domain AAA_29 PF13555.6 CBZ28423.1 - 0.15 11.8 0.4 3.8 7.3 0.0 3.1 4 0 0 4 4 2 0 P-loop containing region of AAA domain IstB_IS21 PF01695.17 CBZ28423.1 - 0.16 11.7 0.6 28 4.4 0.0 3.6 3 0 0 3 3 3 0 IstB-like ATP binding protein AAA_19 PF13245.6 CBZ28423.1 - 0.23 11.8 1.2 66 3.8 0.1 4.2 4 0 0 4 4 3 0 AAA domain AAA_23 PF13476.6 CBZ28423.1 - 0.4 11.1 0.0 0.4 11.1 0.0 4.9 6 0 0 6 6 3 0 AAA domain SRP54 PF00448.22 CBZ28423.1 - 0.65 9.6 3.1 12 5.5 0.0 3.1 3 0 0 3 3 3 0 SRP54-type protein, GTPase domain Pkinase PF00069.25 CBZ28424.1 - 9.7e-51 172.6 0.0 1.6e-50 172.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ28424.1 - 6.6e-36 123.9 0.0 1.1e-35 123.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase BAF1_ABF1 PF04684.13 CBZ28424.1 - 0.52 9.3 1.7 0.79 8.7 1.7 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor ER_lumen_recept PF00810.18 CBZ28425.1 - 1.1e-49 169.1 8.7 1.1e-49 169.1 8.7 1.6 2 0 0 2 2 2 1 ER lumen protein retaining receptor ATP_synt_H PF05493.13 CBZ28426.1 - 7.9e-19 67.9 6.7 8.7e-19 67.8 6.7 1.0 1 0 0 1 1 1 1 ATP synthase subunit H MgtE PF01769.16 CBZ28426.1 - 0.34 11.3 4.8 0.37 11.2 4.8 1.0 1 0 0 1 1 1 0 Divalent cation transporter WD40 PF00400.32 CBZ28427.1 - 2.1e-12 47.3 7.0 0.002 18.9 0.1 6.7 6 1 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBZ28427.1 - 7.2e-12 45.4 0.1 0.0014 18.9 0.0 3.5 3 1 0 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain WD40_3 PF15911.5 CBZ28427.1 - 0.056 13.5 0.0 0.14 12.2 0.0 1.7 1 0 0 1 1 1 0 WD domain, G-beta repeat Ge1_WD40 PF16529.5 CBZ28427.1 - 0.073 12.0 0.6 0.35 9.8 0.4 2.4 2 1 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Ank_4 PF13637.6 CBZ28430.1 - 2e-19 69.6 0.4 5.4e-09 36.4 0.0 3.1 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 CBZ28430.1 - 9.8e-18 64.0 2.5 3.3e-08 33.6 0.2 2.9 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 CBZ28430.1 - 2.6e-17 63.2 2.7 7.5e-12 45.7 0.2 2.0 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 CBZ28430.1 - 1.4e-11 43.5 0.8 0.00074 19.8 0.1 3.6 4 0 0 4 4 4 2 Ankyrin repeat Ank PF00023.30 CBZ28430.1 - 3.1e-06 27.4 1.6 0.0093 16.4 0.2 3.3 3 1 1 4 4 4 2 Ankyrin repeat Metallophos PF00149.28 CBZ28431.1 - 4.9e-37 128.4 0.1 6.4e-37 128.0 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 CBZ28431.1 - 2.3e-17 63.1 1.1 4.3e-17 62.3 1.1 1.5 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain BTB_2 PF02214.22 CBZ28432.1 - 1e-11 45.0 0.0 1.7e-11 44.3 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain DUF4539 PF15072.6 CBZ28433.1 - 4.6e-14 52.2 0.0 7.8e-14 51.5 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4539) SNARE_assoc PF09335.11 CBZ28434.1 - 1.6e-09 38.3 3.8 2.2e-09 37.8 1.0 2.7 2 0 0 2 2 2 1 SNARE associated Golgi protein EF-hand_6 PF13405.6 CBZ28434.1 - 0.00033 20.3 0.0 0.0022 17.8 0.0 2.2 2 0 0 2 2 2 1 EF-hand domain EF-hand_5 PF13202.6 CBZ28434.1 - 0.00044 19.6 0.0 0.001 18.4 0.0 1.6 1 0 0 1 1 1 1 EF hand EF-hand_1 PF00036.32 CBZ28434.1 - 0.0097 15.4 0.0 0.041 13.4 0.0 2.0 2 0 0 2 2 2 1 EF hand EF-hand_7 PF13499.6 CBZ28434.1 - 0.19 12.2 0.0 0.38 11.2 0.0 1.5 1 0 0 1 1 1 0 EF-hand domain pair Sas10_Utp3 PF04000.15 CBZ28435.1 - 9.2e-18 64.7 1.2 2.5e-17 63.3 1.2 1.8 1 0 0 1 1 1 1 Sas10/Utp3/C1D family Sas10 PF09368.10 CBZ28435.1 - 4.2e-15 56.0 4.0 4.2e-15 56.0 4.0 2.0 2 0 0 2 2 2 1 Sas10 C-terminal domain IclR PF01614.18 CBZ28438.1 - 0.096 12.5 0.5 0.12 12.2 0.5 1.2 1 0 0 1 1 1 0 Bacterial transcriptional regulator SNF2_N PF00176.23 CBZ28439.1 - 9.8e-52 175.8 0.0 1.3e-50 172.1 0.0 2.0 1 1 1 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.31 CBZ28439.1 - 2.9e-16 59.8 0.2 7.3e-16 58.5 0.1 1.8 2 0 0 2 2 1 1 Helicase conserved C-terminal domain zf-C3HC4 PF00097.25 CBZ28439.1 - 2.4e-07 30.5 4.7 5.2e-07 29.4 4.7 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CBZ28439.1 - 5.1e-07 29.6 4.5 1.2e-06 28.4 4.5 1.7 1 0 0 1 1 1 1 RING-type zinc-finger ResIII PF04851.15 CBZ28439.1 - 5.2e-07 29.8 0.1 2.5e-06 27.6 0.0 2.1 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit zf-C3HC4_3 PF13920.6 CBZ28439.1 - 2.5e-06 27.2 4.1 5.3e-06 26.2 4.1 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CBZ28439.1 - 2.8e-06 27.2 4.2 2.8e-06 27.2 4.2 1.8 1 1 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.6 CBZ28439.1 - 4.1e-05 23.8 5.4 4.1e-05 23.8 5.4 2.0 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_4 PF15227.6 CBZ28439.1 - 0.00017 21.7 4.2 0.00035 20.6 4.2 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.6 CBZ28439.1 - 0.00063 19.5 10.3 0.0033 17.2 10.3 2.2 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) DEAD PF00270.29 CBZ28439.1 - 0.0015 18.4 0.0 0.0029 17.4 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase ERCC3_RAD25_C PF16203.5 CBZ28439.1 - 0.0021 17.3 0.2 0.0041 16.4 0.2 1.4 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase Prok-RING_4 PF14447.6 CBZ28439.1 - 0.0022 17.8 4.1 0.0062 16.4 4.1 1.8 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 zf-4CXXC_R1 PF10497.9 CBZ28439.1 - 0.0024 18.1 6.1 0.0063 16.7 6.1 1.7 1 0 0 1 1 1 1 Zinc-finger domain of monoamine-oxidase A repressor R1 Sec20 PF03908.13 CBZ28439.1 - 0.12 12.3 1.0 0.98 9.4 0.2 2.5 2 0 0 2 2 2 0 Sec20 zf-rbx1 PF12678.7 CBZ28439.1 - 0.68 10.3 7.7 0.27 11.5 4.3 2.2 1 1 0 1 1 1 0 RING-H2 zinc finger domain DUF4451 PF14616.6 CBZ28439.1 - 0.89 9.8 3.9 6.9 6.9 3.9 2.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4451) PAP_assoc PF03828.19 CBZ28442.1 - 1e-12 48.0 0.0 2.4e-12 46.9 0.0 1.7 1 0 0 1 1 1 1 Cid1 family poly A polymerase DSPc PF00782.20 CBZ28443.1 - 1.3e-17 63.8 0.0 1.3e-16 60.6 0.0 2.3 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain EF-hand_7 PF13499.6 CBZ28444.1 - 1.6e-13 50.9 0.1 4.1e-06 27.2 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_9 PF14658.6 CBZ28444.1 - 8.6e-12 45.2 0.0 1e-09 38.5 0.0 2.1 2 0 0 2 2 2 1 EF-hand domain EF-hand_1 PF00036.32 CBZ28444.1 - 6.8e-11 40.9 1.1 4.4e-05 22.7 0.0 4.1 4 1 1 5 5 5 2 EF hand EF-hand_6 PF13405.6 CBZ28444.1 - 2.8e-10 39.3 1.1 3.4e-05 23.4 0.0 3.4 3 0 0 3 3 3 3 EF-hand domain EF-hand_8 PF13833.6 CBZ28444.1 - 2.9e-07 30.2 0.7 1.8e-05 24.5 0.0 3.5 1 1 3 4 4 4 3 EF-hand domain pair EFhand_Ca_insen PF08726.10 CBZ28444.1 - 0.081 13.0 0.0 0.15 12.2 0.0 1.4 1 0 0 1 1 1 0 Ca2+ insensitive EF hand EF-hand_5 PF13202.6 CBZ28444.1 - 1.2 8.7 3.7 21 4.8 0.0 3.5 3 1 1 4 4 4 0 EF hand RNA_pol_Rpb8 PF03870.15 CBZ28445.1 - 5.4e-36 123.8 0.0 6.1e-36 123.7 0.0 1.0 1 0 0 1 1 1 1 RNA polymerase Rpb8 RNA_pol_RpbG PF16992.5 CBZ28445.1 - 0.0013 18.8 0.2 0.56 10.3 0.0 2.1 2 0 0 2 2 2 2 DNA-directed RNA polymerase, subunit G Myco_19_kDa PF05481.12 CBZ28445.1 - 0.065 13.5 0.1 0.087 13.1 0.1 1.2 1 0 0 1 1 1 0 Mycobacterium 19 kDa lipoprotein antigen PP_kinase_C PF13090.6 CBZ28446.1 - 0.2 11.1 0.0 0.37 10.2 0.0 1.3 1 0 0 1 1 1 0 Polyphosphate kinase C-terminal domain 2 CSD PF00313.22 CBZ28448.1 - 2.5e-15 56.1 0.2 3.3e-15 55.7 0.2 1.2 1 0 0 1 1 1 1 'Cold-shock' DNA-binding domain DUF5318 PF17249.2 CBZ28449.1 - 0.005 16.6 2.3 0.28 10.9 0.2 2.4 2 0 0 2 2 2 2 Family of unknown function (DUF5318) FXMRP1_C_core PF12235.8 CBZ28450.1 - 0.00039 21.1 2.0 0.00051 20.7 2.0 1.2 1 0 0 1 1 1 1 Fragile X-related 1 protein core C terminal OrfB_IS605 PF01385.19 CBZ28450.1 - 0.052 13.8 0.7 0.14 12.4 0.0 1.9 2 0 0 2 2 2 0 Probable transposase HTH_46 PF15977.5 CBZ28450.1 - 0.087 12.9 0.0 0.13 12.2 0.0 1.3 1 0 0 1 1 1 0 Winged helix-turn-helix DNA binding Chorion_3 PF05387.11 CBZ28450.1 - 0.11 12.2 1.1 0.12 12.0 1.1 1.1 1 0 0 1 1 1 0 Chorion family 3 DUF1738 PF08401.11 CBZ28451.1 - 0.08 13.0 0.0 3.1 7.9 0.0 3.0 4 0 0 4 4 4 0 Domain of unknown function (DUF1738) MCM PF00493.23 CBZ28452.1 - 3.8e-93 310.7 0.0 5.9e-93 310.1 0.0 1.3 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 CBZ28452.1 - 1.2e-35 122.1 0.1 2.1e-35 121.3 0.1 1.4 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 CBZ28452.1 - 1.1e-26 93.1 0.1 2.5e-26 91.9 0.1 1.7 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 CBZ28452.1 - 1.2e-09 38.7 3.8 1.4e-09 38.4 0.9 2.5 2 0 0 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.21 CBZ28452.1 - 1.2e-07 31.3 0.0 1.3e-05 24.7 0.0 2.6 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI MCM2_N PF12619.8 CBZ28452.1 - 3.1e-06 27.6 23.0 3.1e-06 27.6 23.0 3.4 5 0 0 5 5 4 1 Mini-chromosome maintenance protein 2 AAA_5 PF07728.14 CBZ28452.1 - 1.8e-05 24.8 0.0 3.9e-05 23.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 CBZ28452.1 - 0.0017 18.2 0.0 0.0081 16.0 0.0 2.1 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_lid_2 PF17863.1 CBZ28452.1 - 0.0059 16.4 0.2 0.024 14.5 0.2 2.0 1 0 0 1 1 1 1 AAA lid domain AAA PF00004.29 CBZ28452.1 - 0.044 14.2 0.0 0.12 12.7 0.0 1.8 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 CBZ28452.1 - 0.12 12.1 0.0 0.49 10.1 0.0 1.9 1 1 0 1 1 1 0 Sigma-54 interaction domain DUF2757 PF10955.8 CBZ28452.1 - 0.17 12.1 0.4 40 4.6 0.3 3.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2757) CagY_M PF07337.11 CBZ28452.1 - 0.25 11.0 3.6 0.29 10.8 1.4 2.1 2 0 0 2 2 2 0 DC-EC Repeat DUF2267 PF10025.9 CBZ28453.1 - 0.13 12.6 0.1 1.5 9.1 0.2 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2267) Baculo_11_kDa PF06143.11 CBZ28454.1 - 0.097 12.3 0.0 0.25 10.9 0.0 1.7 1 0 0 1 1 1 0 Baculovirus 11 kDa family Ribonuc_red_lgC PF02867.15 CBZ28456.1 - 6.5e-183 609.0 0.0 8e-183 608.7 0.0 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, barrel domain Ribonuc_red_lgN PF00317.21 CBZ28456.1 - 9.1e-24 83.3 0.0 2.4e-23 81.9 0.0 1.8 1 0 0 1 1 1 1 Ribonucleotide reductase, all-alpha domain ATP-cone PF03477.16 CBZ28456.1 - 3.9e-12 46.6 0.0 8.9e-12 45.4 0.0 1.7 1 0 0 1 1 1 1 ATP cone domain Lebercilin PF15619.6 CBZ28457.1 - 0.0024 17.6 31.0 0.2 11.3 26.9 3.2 2 1 0 2 2 2 1 Ciliary protein causing Leber congenital amaurosis disease Filament PF00038.21 CBZ28457.1 - 0.069 12.7 24.3 0.87 9.1 8.3 2.3 1 1 1 2 2 2 0 Intermediate filament protein T5orf172 PF10544.9 CBZ28457.1 - 0.15 12.6 1.9 0.22 12.1 0.8 1.9 1 1 0 1 1 1 0 T5orf172 domain CarD_CdnL_TRCF PF02559.16 CBZ28457.1 - 1.8 9.3 4.5 1.5 9.6 0.7 2.3 1 1 1 2 2 2 0 CarD-like/TRCF domain Fib_alpha PF08702.10 CBZ28457.1 - 2.9 8.1 12.7 16 5.7 11.2 2.7 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family Baculo_PEP_C PF04513.12 CBZ28457.1 - 6.2 6.9 7.7 9 6.3 1.8 2.9 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus APG6_N PF17675.1 CBZ28457.1 - 9.1 6.8 31.4 2 9.0 12.1 3.2 2 1 1 3 3 3 0 Apg6 coiled-coil region Exo_endo_phos PF03372.23 CBZ28458.1 - 0.00019 21.0 0.0 0.16 11.4 0.0 3.7 2 1 0 2 2 2 2 Endonuclease/Exonuclease/phosphatase family Pertus-S4-tox PF09275.10 CBZ28458.1 - 0.13 12.6 0.3 3.4 8.0 0.0 3.1 3 0 0 3 3 3 0 Pertussis toxin S4 subunit DUF4381 PF14316.6 CBZ28460.1 - 0.065 13.5 0.4 0.065 13.5 0.4 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4381) adh_short PF00106.25 CBZ28461.1 - 1.5e-15 57.1 0.0 8.8e-09 35.1 0.0 2.3 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 CBZ28461.1 - 2.1e-12 47.1 0.0 4.1e-07 29.8 0.0 2.3 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase Tctex-1 PF03645.13 CBZ28462.1 - 8.2e-25 87.0 0.1 9.7e-25 86.8 0.1 1.1 1 0 0 1 1 1 1 Tctex-1 family Ribosomal_S11 PF00411.19 CBZ28463.1 - 4.4e-47 159.0 1.7 5.6e-47 158.7 1.7 1.1 1 0 0 1 1 1 1 Ribosomal protein S11 LSM PF01423.22 CBZ28464.1 - 0.0046 16.6 0.0 0.007 16.0 0.0 1.4 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 CBZ28464.1 - 0.022 14.9 0.0 0.037 14.1 0.0 1.5 1 1 0 1 1 1 0 Ataxin 2 SM domain B12D PF06522.11 CBZ28465.1 - 0.043 13.6 0.2 0.095 12.5 0.2 1.5 1 0 0 1 1 1 0 NADH-ubiquinone reductase complex 1 MLRQ subunit MtN3_slv PF03083.16 CBZ28465.1 - 0.073 13.1 0.3 0.12 12.4 0.3 1.3 1 0 0 1 1 1 0 Sugar efflux transporter for intercellular exchange Serinc PF03348.15 CBZ28466.1 - 5.4e-54 183.7 36.7 3.9e-53 180.9 36.7 1.8 1 1 0 1 1 1 1 Serine incorporator (Serinc) DUF3899 PF13038.6 CBZ28466.1 - 1.7 9.2 12.8 17 6.0 9.3 4.1 2 2 0 2 2 2 0 Domain of unknown function (DUF3899) Ribosomal_S10 PF00338.22 CBZ28468.1 - 5.6e-24 84.2 0.3 6.5e-24 84.0 0.3 1.0 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e PriA_C PF18074.1 CBZ28468.1 - 0.15 12.9 0.0 0.3 11.9 0.0 1.5 2 0 0 2 2 2 0 Primosomal protein N C-terminal domain Ribosomal_S10 PF00338.22 CBZ28469.1 - 5.6e-24 84.2 0.3 6.5e-24 84.0 0.3 1.0 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e PriA_C PF18074.1 CBZ28469.1 - 0.15 12.9 0.0 0.3 11.9 0.0 1.5 2 0 0 2 2 2 0 Primosomal protein N C-terminal domain PPR PF01535.20 CBZ28470.1 - 1.9e-05 24.6 0.6 0.2 12.0 0.0 4.9 5 0 0 5 5 5 1 PPR repeat PPR_2 PF13041.6 CBZ28470.1 - 3.7e-05 23.8 0.0 1.2 9.4 0.0 5.0 5 1 1 6 6 6 2 PPR repeat family PPR_3 PF13812.6 CBZ28470.1 - 0.012 15.6 0.0 0.42 10.7 0.0 2.7 2 0 0 2 2 2 0 Pentatricopeptide repeat domain PPR_long PF17177.4 CBZ28470.1 - 0.039 13.3 1.6 0.5 9.7 0.0 2.9 3 0 0 3 3 3 0 Pentacotripeptide-repeat region of PRORP Ribosomal_S10 PF00338.22 CBZ28471.1 - 5.6e-24 84.2 0.3 6.5e-24 84.0 0.3 1.0 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e PriA_C PF18074.1 CBZ28471.1 - 0.15 12.9 0.0 0.3 11.9 0.0 1.5 2 0 0 2 2 2 0 Primosomal protein N C-terminal domain FlxA PF14282.6 CBZ28472.1 - 0.0052 16.7 1.6 0.0052 16.7 1.6 2.6 2 0 0 2 2 2 1 FlxA-like protein CENP-F_leu_zip PF10473.9 CBZ28472.1 - 5.4 7.0 10.0 5.4 7.0 2.3 3.2 3 0 0 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 HMG_box_2 PF09011.10 CBZ28476.1 - 0.0053 17.3 1.3 3.2 8.4 0.1 2.8 2 0 0 2 2 2 2 HMG-box domain ATP-grasp_4 PF13535.6 CBZ28477.1 - 2.5e-09 36.9 0.1 2.5e-07 30.4 0.1 2.4 2 0 0 2 2 2 1 ATP-grasp domain ATP-grasp_3 PF02655.14 CBZ28477.1 - 3.3e-06 27.2 0.0 0.00017 21.7 0.0 2.4 2 0 0 2 2 2 1 ATP-grasp domain CPSase_L_D2 PF02786.17 CBZ28477.1 - 8.3e-05 22.2 0.0 0.0057 16.2 0.0 2.2 2 0 0 2 2 2 1 Carbamoyl-phosphate synthase L chain, ATP binding domain GARS_A PF01071.19 CBZ28477.1 - 0.0005 19.9 0.1 0.0011 18.7 0.1 1.6 1 1 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain ATPgrasp_Ter PF15632.6 CBZ28477.1 - 0.0049 16.6 0.0 3.2 7.5 0.0 2.7 2 0 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon RimK PF08443.11 CBZ28477.1 - 0.2 11.3 0.0 0.35 10.4 0.0 1.4 1 0 0 1 1 1 0 RimK-like ATP-grasp domain ubiquitin PF00240.23 CBZ28479.1 - 2.3e-05 24.0 0.1 4.5e-05 23.1 0.1 1.4 1 0 0 1 1 1 1 Ubiquitin family WD40 PF00400.32 CBZ28480.1 - 1.9e-34 117.1 28.8 0.00014 22.6 0.0 10.5 10 0 0 10 10 10 9 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBZ28480.1 - 1.5e-14 54.0 0.4 0.013 15.8 0.0 6.5 5 2 2 7 7 7 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 CBZ28480.1 - 1.1e-05 25.4 0.0 0.43 10.4 0.0 3.3 3 0 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 CBZ28480.1 - 0.00042 19.7 0.5 0.17 11.2 0.8 3.3 2 1 1 3 3 3 1 WD40-like domain Gmad1 PF10647.9 CBZ28480.1 - 0.036 13.8 0.1 6.7 6.4 0.0 2.8 2 0 0 2 2 2 0 Lipoprotein LpqB beta-propeller domain WD40_3 PF15911.5 CBZ28480.1 - 0.075 13.1 1.5 2.2 8.4 0.0 3.5 4 0 0 4 4 4 0 WD domain, G-beta repeat PQQ_3 PF13570.6 CBZ28480.1 - 0.11 13.0 9.8 1e+02 3.6 0.0 6.7 6 1 0 6 6 6 0 PQQ-like domain Amastin PF07344.11 CBZ28481.1 - 0.0022 17.8 11.9 0.0039 17.1 11.9 1.4 1 1 0 1 1 1 1 Amastin surface glycoprotein PMP22_Claudin PF00822.20 CBZ28481.1 - 0.21 11.5 11.6 0.5 10.2 11.7 1.6 1 1 0 1 1 1 0 PMP-22/EMP/MP20/Claudin family Amastin PF07344.11 CBZ28482.1 - 1.8e-30 105.8 23.8 4.8e-19 68.7 5.7 2.4 2 0 0 2 2 2 2 Amastin surface glycoprotein DUF5134 PF17197.4 CBZ28482.1 - 3.7 7.4 7.6 2 8.3 0.5 3.5 2 1 1 3 3 3 0 Domain of unknown function (DUF5134) ETF_alpha PF00766.19 CBZ28483.1 - 5.1e-36 122.6 0.8 1.3e-35 121.3 0.2 2.0 2 0 0 2 2 2 1 Electron transfer flavoprotein FAD-binding domain ETF PF01012.21 CBZ28483.1 - 1.7e-28 99.8 5.6 2.7e-28 99.1 5.6 1.3 1 0 0 1 1 1 1 Electron transfer flavoprotein domain AMP-binding PF00501.28 CBZ28484.1 - 3e-52 177.6 0.6 4.1e-49 167.3 0.2 3.0 2 1 0 2 2 2 2 AMP-binding enzyme AMP-binding_C PF13193.6 CBZ28484.1 - 3.6e-10 40.7 0.5 8.8e-10 39.4 0.5 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain ATP-synt_C PF00137.21 CBZ28485.1 - 8.2e-26 90.1 49.2 6.4e-19 68.0 13.6 3.1 3 0 0 3 3 3 3 ATP synthase subunit C LRR_6 PF13516.6 CBZ28486.1 - 0.0017 18.3 0.3 0.0017 18.3 0.3 3.8 4 0 0 4 4 4 1 Leucine Rich repeat LRR_4 PF12799.7 CBZ28486.1 - 0.0093 16.4 0.9 5.7 7.5 0.0 2.8 2 0 0 2 2 2 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CBZ28486.1 - 0.023 14.5 3.7 1.4 8.7 0.1 3.5 4 0 0 4 4 4 0 Leucine rich repeat zf-AN1 PF01428.16 CBZ28487.1 - 2.2e-08 34.1 10.3 3.4e-08 33.5 10.3 1.3 1 0 0 1 1 1 1 AN1-like Zinc finger Transp_Tc5_C PF04236.15 CBZ28487.1 - 0.00044 20.6 3.8 0.00068 19.9 3.8 1.3 1 0 0 1 1 1 1 Tc5 transposase C-terminal domain PhnG PF06754.12 CBZ28487.1 - 0.41 10.6 6.1 0.52 10.3 6.1 1.1 1 0 0 1 1 1 0 Phosphonate metabolism protein PhnG Copine PF07002.16 CBZ28489.1 - 5.2e-66 222.2 0.0 7.5e-66 221.7 0.0 1.2 1 0 0 1 1 1 1 Copine C2 PF00168.30 CBZ28489.1 - 8.8e-27 93.4 0.0 8.6e-13 48.5 0.0 2.4 2 0 0 2 2 2 2 C2 domain vWA-TerF-like PF10138.9 CBZ28489.1 - 0.00022 21.4 0.0 0.00041 20.5 0.0 1.5 1 0 0 1 1 1 1 vWA found in TerF C terminus VWA PF00092.28 CBZ28489.1 - 0.018 15.3 0.0 0.031 14.5 0.0 1.2 1 0 0 1 1 1 0 von Willebrand factor type A domain HSP70 PF00012.20 CBZ28490.1 - 4.2e-250 831.1 12.2 4.8e-250 830.9 12.2 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 CBZ28490.1 - 1.5e-21 76.6 0.4 5.9e-19 68.0 0.1 2.3 1 1 0 2 2 2 2 MreB/Mbl protein FGGY_C PF02782.16 CBZ28490.1 - 0.0019 18.0 0.0 0.005 16.6 0.0 1.8 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain Hydantoinase_A PF01968.18 CBZ28490.1 - 0.025 13.8 3.7 0.039 13.2 0.1 2.8 3 0 0 3 3 3 0 Hydantoinase/oxoprolinase DUF2706 PF10913.8 CBZ28490.1 - 0.041 13.7 0.2 6.2 6.7 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2706) FIVAR PF07554.13 CBZ28490.1 - 0.37 11.6 2.3 0.79 10.5 0.6 2.5 2 0 0 2 2 2 0 FIVAR domain DUF1542 PF07564.11 CBZ28490.1 - 3.1 8.0 8.9 0.45 10.6 1.5 2.9 2 1 1 3 3 3 0 Domain of Unknown Function (DUF1542) RCR PF12273.8 CBZ28491.1 - 1.2 9.8 7.0 0.85 10.3 0.2 2.9 3 0 0 3 3 3 0 Chitin synthesis regulation, resistance to Congo red WWE PF02825.20 CBZ28492.1 - 0.0013 19.3 0.0 0.0032 18.0 0.0 1.7 1 0 0 1 1 1 1 WWE domain BUD22 PF09073.10 CBZ28492.1 - 0.02 14.2 9.1 0.017 14.5 4.4 2.1 2 0 0 2 2 2 0 BUD22 CDC45 PF02724.14 CBZ28492.1 - 8.5 4.5 9.1 16 3.7 9.1 1.4 1 0 0 1 1 1 0 CDC45-like protein SGL PF08450.12 CBZ28493.1 - 6e-39 134.1 0.0 2.9e-38 131.9 0.0 2.0 1 1 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region FAD_binding_1 PF00667.20 CBZ28494.1 - 4.5e-39 134.3 0.0 7.3e-39 133.6 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.25 CBZ28494.1 - 5.6e-34 117.4 0.7 2.8e-33 115.1 0.2 2.3 2 1 1 3 3 3 1 Flavodoxin NAD_binding_1 PF00175.21 CBZ28494.1 - 3.3e-13 50.2 0.0 1.4e-12 48.2 0.0 2.1 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain BILBO1_N PF18281.1 CBZ28495.1 - 5.5e-29 100.4 0.2 1.3e-28 99.2 0.2 1.7 1 0 0 1 1 1 1 BILBO1 N-terminal domain Exonuc_VII_L PF02601.15 CBZ28495.1 - 0.0017 18.0 0.6 0.0023 17.6 0.6 1.3 1 0 0 1 1 1 1 Exonuclease VII, large subunit Occludin_ELL PF07303.13 CBZ28495.1 - 0.051 14.3 4.4 0.16 12.7 4.4 1.8 1 0 0 1 1 1 0 Occludin homology domain EMP24_GP25L PF01105.24 CBZ28495.1 - 0.46 10.4 2.9 0.79 9.6 2.9 1.3 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD DUF4140 PF13600.6 CBZ28495.1 - 0.66 10.4 10.4 0.048 14.1 4.9 1.9 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) DnaJ PF00226.31 CBZ28497.1 - 2e-16 59.9 0.5 4e-16 58.9 0.5 1.5 1 0 0 1 1 1 1 DnaJ domain Orexin PF02072.15 CBZ28497.1 - 0.084 12.8 0.3 4.6 7.2 0.1 2.3 2 0 0 2 2 2 0 Prepro-orexin Biopterin_H PF00351.21 CBZ28498.1 - 4.4e-131 436.9 0.0 5.7e-131 436.5 0.0 1.1 1 0 0 1 1 1 1 Biopterin-dependent aromatic amino acid hydroxylase ExbD PF02472.16 CBZ28498.1 - 0.14 12.3 0.0 0.24 11.6 0.0 1.3 1 0 0 1 1 1 0 Biopolymer transport protein ExbD/TolR Glyco_hydro_92N PF17678.1 CBZ28499.1 - 0.082 12.8 0.7 1.6 8.6 0.0 2.3 2 0 0 2 2 2 0 Glycosyl hydrolase family 92 N-terminal domain zf-RING_UBOX PF13445.6 CBZ28500.1 - 5.2e-06 26.4 12.5 9.9e-06 25.5 12.5 1.4 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 CBZ28500.1 - 2.9e-05 23.8 7.4 4.9e-05 23.1 7.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 CBZ28500.1 - 3e-05 23.8 11.4 5.2e-05 23.0 11.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CBZ28500.1 - 5.5e-05 22.9 9.3 9.5e-05 22.2 9.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CBZ28500.1 - 6.8e-05 22.7 7.1 0.00011 22.0 7.1 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 CBZ28500.1 - 0.00012 22.1 14.1 0.00019 21.5 14.1 1.3 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.6 CBZ28500.1 - 0.00025 21.3 9.9 0.00044 20.5 9.9 1.5 1 0 0 1 1 1 1 Ring finger domain Prok-RING_4 PF14447.6 CBZ28500.1 - 0.013 15.3 9.3 0.053 13.4 9.7 1.8 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 zf-C2H2_3 PF13878.6 CBZ28500.1 - 0.019 14.8 0.5 0.25 11.2 0.1 2.3 2 0 0 2 2 2 0 zinc-finger of acetyl-transferase ESCO zf-ribbon_3 PF13248.6 CBZ28500.1 - 0.067 12.6 1.2 2.4 7.7 0.1 2.5 2 0 0 2 2 2 0 zinc-ribbon domain Matrilin_ccoil PF10393.9 CBZ28500.1 - 0.23 11.3 4.9 4.3 7.3 0.5 3.1 2 1 0 2 2 2 0 Trimeric coiled-coil oligomerisation domain of matrilin zf-RING_6 PF14835.6 CBZ28500.1 - 0.24 11.3 5.3 0.68 9.8 5.3 1.7 1 1 0 1 1 1 0 zf-RING of BARD1-type protein Spc7 PF08317.11 CBZ28500.1 - 0.28 10.0 10.1 0.071 12.0 6.7 1.6 2 0 0 2 2 2 0 Spc7 kinetochore protein Rad50_zn_hook PF04423.14 CBZ28500.1 - 0.59 10.0 0.0 0.59 10.0 0.0 3.9 5 0 0 5 5 5 0 Rad50 zinc hook motif zf-Nse PF11789.8 CBZ28500.1 - 0.78 9.6 3.7 1.8 8.4 3.7 1.6 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit FapA PF03961.13 CBZ28500.1 - 1.3 7.5 5.3 1.3 7.6 3.4 1.8 2 0 0 2 2 2 0 Flagellar Assembly Protein A zf-HIT PF04438.16 CBZ28500.1 - 1.8 8.5 5.6 0.73 9.8 1.2 2.1 2 0 0 2 2 2 0 HIT zinc finger DZR PF12773.7 CBZ28500.1 - 3.1 7.9 6.6 14 5.8 6.9 1.8 1 1 0 1 1 1 0 Double zinc ribbon Fib_alpha PF08702.10 CBZ28500.1 - 4.1 7.6 10.5 15 5.7 0.2 3.8 3 1 1 4 4 4 0 Fibrinogen alpha/beta chain family XhlA PF10779.9 CBZ28500.1 - 7.9 6.8 7.0 21 5.4 0.5 3.6 2 1 1 3 3 3 0 Haemolysin XhlA BST2 PF16716.5 CBZ28500.1 - 8.4 7.1 12.9 2.3 8.8 6.8 2.8 2 1 1 3 3 3 0 Bone marrow stromal antigen 2 DEAD PF00270.29 CBZ28501.1 - 9.8e-42 142.7 0.0 1.6e-41 142.0 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CBZ28501.1 - 3.7e-25 88.4 0.0 1.2e-24 86.8 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 CBZ28501.1 - 2.6e-11 43.6 0.1 6.3e-11 42.3 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.15 CBZ28501.1 - 2.9e-07 30.6 0.0 8.4e-07 29.1 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DUF2753 PF10952.8 CBZ28501.1 - 0.015 15.4 0.1 0.033 14.3 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2753) DUF3160 PF11369.8 CBZ28501.1 - 0.027 13.0 0.1 0.052 12.0 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3160) DUF2500 PF10694.9 CBZ28501.1 - 0.13 12.8 0.3 0.33 11.5 0.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2500) UbiA PF01040.18 CBZ28502.1 - 7.2e-36 123.8 18.7 9.5e-36 123.4 18.1 1.5 1 1 0 1 1 1 1 UbiA prenyltransferase family Hydrolase_3 PF08282.12 CBZ28504.1 - 5.3e-20 72.2 0.0 8.3e-19 68.3 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase S6PP PF05116.13 CBZ28504.1 - 1.1e-05 25.1 0.0 1.7e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 Sucrose-6F-phosphate phosphohydrolase Hydrolase_3 PF08282.12 CBZ28505.1 - 5.2e-36 124.7 0.1 1.5e-34 119.9 0.1 2.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase S6PP PF05116.13 CBZ28505.1 - 1.1e-09 38.2 0.0 0.00021 20.9 0.0 2.3 2 0 0 2 2 2 2 Sucrose-6F-phosphate phosphohydrolase Trehalose_PPase PF02358.16 CBZ28505.1 - 0.01 15.0 0.0 4.4 6.4 0.0 2.3 2 0 0 2 2 2 0 Trehalose-phosphatase Hydrolase PF00702.26 CBZ28505.1 - 0.018 15.4 3.8 2.7 8.2 0.5 2.6 2 1 0 2 2 2 0 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 CBZ28506.1 - 3.2e-52 177.8 0.0 5.3e-52 177.1 0.0 1.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase S6PP PF05116.13 CBZ28506.1 - 7e-16 58.5 0.0 4.7e-07 29.6 0.0 2.1 2 0 0 2 2 2 2 Sucrose-6F-phosphate phosphohydrolase Hydrolase PF00702.26 CBZ28506.1 - 1.4e-10 41.8 0.1 7.3e-05 23.2 0.0 2.3 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase HAD PF12710.7 CBZ28506.1 - 7.2e-06 26.5 1.6 0.0035 17.8 0.0 2.9 2 1 1 3 3 3 2 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.6 CBZ28506.1 - 0.0044 17.1 0.0 0.014 15.5 0.0 2.0 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 CBZ28506.1 - 0.0055 16.8 0.2 1.8 8.6 0.1 2.5 2 0 0 2 2 2 2 Haloacid dehalogenase-like hydrolase Bmp PF02608.14 CBZ28506.1 - 0.17 10.8 0.0 0.26 10.2 0.0 1.2 1 0 0 1 1 1 0 ABC transporter substrate-binding protein PnrA-like Hydrolase_3 PF08282.12 CBZ28507.1 - 3.6e-52 177.6 0.0 4.3e-52 177.4 0.0 1.1 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase S6PP PF05116.13 CBZ28507.1 - 4.2e-19 69.1 0.0 8.3e-09 35.3 0.0 2.1 2 0 0 2 2 2 2 Sucrose-6F-phosphate phosphohydrolase Hydrolase PF00702.26 CBZ28507.1 - 8.3e-07 29.5 0.1 9.8e-06 26.0 0.1 2.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 CBZ28507.1 - 0.017 15.5 0.6 5.9 7.3 0.0 3.5 1 1 2 3 3 3 0 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 CBZ28507.1 - 0.034 14.2 0.0 0.83 9.7 0.0 2.4 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.6 CBZ28507.1 - 0.039 14.1 0.0 0.1 12.8 0.0 1.8 1 1 0 1 1 1 0 Haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 CBZ28508.1 - 9.8e-49 166.4 0.0 1.1e-31 110.5 0.0 2.2 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase S6PP PF05116.13 CBZ28508.1 - 1.5e-14 54.1 0.0 3.3e-09 36.7 0.0 2.2 2 0 0 2 2 2 2 Sucrose-6F-phosphate phosphohydrolase Hydrolase PF00702.26 CBZ28508.1 - 2.6e-08 34.4 0.0 0.0055 17.0 0.0 2.5 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase HAD PF12710.7 CBZ28508.1 - 0.00065 20.2 0.1 0.46 10.9 0.0 2.5 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 CBZ28508.1 - 0.42 10.7 4.7 3.5 7.7 0.0 2.8 3 0 0 3 3 3 0 Haloacid dehalogenase-like hydrolase Amastin PF07344.11 CBZ28509.1 - 7.6e-46 155.8 4.6 1e-45 155.4 4.6 1.1 1 0 0 1 1 1 1 Amastin surface glycoprotein Amastin PF07344.11 CBZ28510.1 - 8.1e-32 110.2 8.3 1.4e-31 109.5 8.3 1.4 1 0 0 1 1 1 1 Amastin surface glycoprotein zf-CCCH_4 PF18044.1 CBZ28511.1 - 9.3e-06 25.3 6.4 1.6e-05 24.5 6.4 1.4 1 0 0 1 1 1 1 CCCH-type zinc finger zf-CCCH PF00642.24 CBZ28511.1 - 0.00019 21.3 4.0 0.00035 20.4 4.0 1.5 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 CBZ28511.1 - 0.00023 21.1 6.7 0.00042 20.3 6.7 1.4 1 0 0 1 1 1 1 Zinc finger domain Torus PF16131.5 CBZ28511.1 - 0.00078 20.1 0.8 0.0014 19.3 0.8 1.3 1 0 0 1 1 1 1 Torus domain zf-CCCH_2 PF14608.6 CBZ28511.1 - 0.011 16.1 7.4 0.011 16.1 7.4 1.8 2 0 0 2 2 2 0 RNA-binding, Nab2-type zinc finger IMS PF00817.20 CBZ28512.1 - 8e-35 120.0 0.0 1.8e-34 118.9 0.0 1.6 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.8 CBZ28512.1 - 5.2e-12 46.5 0.2 1.7e-11 44.8 0.2 1.9 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.8 CBZ28512.1 - 3.5e-05 23.9 0.0 9e-05 22.6 0.0 1.8 1 0 0 1 1 1 1 IMS family HHH motif SPX PF03105.19 CBZ28512.1 - 0.00016 21.7 1.4 0.00016 21.7 1.4 2.0 2 0 0 2 2 2 1 SPX domain IMS PF00817.20 CBZ28513.1 - 6.9e-39 133.2 0.0 1.2e-38 132.4 0.0 1.4 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.8 CBZ28513.1 - 1.4e-11 45.2 1.2 2.2e-11 44.5 0.2 1.8 2 0 0 2 2 2 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.8 CBZ28513.1 - 0.00047 20.3 0.0 0.0014 18.9 0.0 1.9 1 0 0 1 1 1 1 IMS family HHH motif Ribosomal_L6e PF01159.19 CBZ28513.1 - 7.6 7.1 6.9 4.8 7.7 3.6 2.3 2 0 0 2 2 2 0 Ribosomal protein L6e IMS PF00817.20 CBZ28514.1 - 9.1e-37 126.4 0.0 1.5e-36 125.6 0.0 1.4 1 0 0 1 1 1 1 impB/mucB/samB family IMS_HHH PF11798.8 CBZ28514.1 - 5.5e-06 26.4 0.0 1.3e-05 25.2 0.0 1.7 1 0 0 1 1 1 1 IMS family HHH motif IMS_C PF11799.8 CBZ28514.1 - 2.6e-05 24.9 0.0 5.6e-05 23.8 0.0 1.5 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain Cdd1 PF11731.8 CBZ28514.1 - 0.13 12.5 0.0 0.35 11.1 0.0 1.6 1 0 0 1 1 1 0 Pathogenicity locus IMS PF00817.20 CBZ28515.1 - 0.033 14.2 1.1 0.79 9.7 0.3 3.0 1 1 1 2 2 2 0 impB/mucB/samB family DUF2163 PF09931.9 CBZ28516.1 - 0.052 13.8 0.0 0.13 12.5 0.0 1.6 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2163) AAA PF00004.29 CBZ28517.1 - 8.9e-32 110.3 0.0 2.1e-21 76.7 0.0 3.4 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 CBZ28517.1 - 4.4e-11 43.4 5.7 3e-08 34.2 0.1 3.5 3 2 1 4 4 3 2 AAA ATPase domain AAA_22 PF13401.6 CBZ28517.1 - 2.1e-08 34.5 0.1 5.9e-05 23.3 0.0 3.4 3 1 0 3 3 2 1 AAA domain AAA_5 PF07728.14 CBZ28517.1 - 4.2e-08 33.3 0.0 9.7e-06 25.6 0.0 2.7 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_33 PF13671.6 CBZ28517.1 - 6.2e-08 32.9 0.0 0.00032 20.9 0.0 2.8 2 1 0 2 2 2 2 AAA domain IstB_IS21 PF01695.17 CBZ28517.1 - 8.3e-08 32.2 0.0 0.00046 20.0 0.0 2.5 2 0 0 2 2 2 2 IstB-like ATP binding protein RuvB_N PF05496.12 CBZ28517.1 - 1.2e-06 28.3 0.0 6.7e-05 22.7 0.0 2.5 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain TniB PF05621.11 CBZ28517.1 - 3.4e-06 26.6 0.0 0.0064 15.9 0.0 3.1 3 0 0 3 3 3 2 Bacterial TniB protein Mg_chelatase PF01078.21 CBZ28517.1 - 7.3e-06 25.5 0.2 0.0039 16.6 0.1 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_14 PF13173.6 CBZ28517.1 - 1e-05 25.6 0.0 3.4e-05 23.9 0.0 1.8 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 CBZ28517.1 - 1.1e-05 25.7 0.0 0.015 15.6 0.0 2.4 2 0 0 2 2 2 1 RNA helicase AAA_25 PF13481.6 CBZ28517.1 - 6e-05 22.7 0.9 0.1 12.2 0.0 3.0 2 1 0 3 3 3 2 AAA domain AAA_7 PF12775.7 CBZ28517.1 - 9.6e-05 22.0 0.0 0.056 13.0 0.0 2.4 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_2 PF07724.14 CBZ28517.1 - 0.00036 20.7 0.0 0.044 13.9 0.0 2.4 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) NACHT PF05729.12 CBZ28517.1 - 0.00052 20.0 0.0 0.024 14.6 0.0 2.7 2 0 0 2 2 2 1 NACHT domain DUF815 PF05673.13 CBZ28517.1 - 0.00053 19.2 0.0 0.052 12.7 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_11 PF13086.6 CBZ28517.1 - 0.0011 18.8 0.0 0.059 13.1 0.0 2.2 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.12 CBZ28517.1 - 0.0012 18.2 0.0 1.1 8.4 0.0 2.4 2 0 0 2 2 2 2 Zeta toxin TIP49 PF06068.13 CBZ28517.1 - 0.0013 18.0 0.0 0.0038 16.5 0.0 1.6 2 0 0 2 2 2 1 TIP49 P-loop domain TsaE PF02367.17 CBZ28517.1 - 0.0016 18.5 0.0 0.12 12.3 0.0 2.8 3 0 0 3 3 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE T2SSE PF00437.20 CBZ28517.1 - 0.0016 17.6 0.0 0.82 8.7 0.0 2.6 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_28 PF13521.6 CBZ28517.1 - 0.0022 18.2 0.0 0.35 11.1 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 CBZ28517.1 - 0.0032 17.2 0.0 2.1 8.2 0.0 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain ABC_tran PF00005.27 CBZ28517.1 - 0.0059 17.1 0.0 0.17 12.4 0.0 2.4 2 0 0 2 2 2 1 ABC transporter AAA_18 PF13238.6 CBZ28517.1 - 0.009 16.6 0.0 0.091 13.3 0.0 2.2 2 0 0 2 2 2 1 AAA domain Sigma54_activat PF00158.26 CBZ28517.1 - 0.0095 15.7 0.0 0.16 11.7 0.0 2.2 2 0 0 2 2 2 1 Sigma-54 interaction domain MCM PF00493.23 CBZ28517.1 - 0.0097 15.0 0.0 0.22 10.6 0.0 2.2 2 0 0 2 2 2 1 MCM P-loop domain AAA_3 PF07726.11 CBZ28517.1 - 0.018 14.9 0.0 0.042 13.7 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 CBZ28517.1 - 0.023 14.2 0.0 0.12 11.8 0.0 2.0 2 0 0 2 2 2 0 PhoH-like protein AAA_24 PF13479.6 CBZ28517.1 - 0.03 14.1 0.0 0.15 11.7 0.0 2.0 2 0 0 2 2 2 0 AAA domain CPT PF07931.12 CBZ28517.1 - 0.031 14.1 0.0 0.45 10.3 0.0 2.4 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein Cytidylate_kin PF02224.18 CBZ28517.1 - 0.04 13.7 0.0 0.75 9.5 0.0 2.3 2 0 0 2 2 2 0 Cytidylate kinase AAA_30 PF13604.6 CBZ28517.1 - 0.04 13.6 0.0 0.31 10.7 0.0 2.3 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.15 CBZ28517.1 - 0.054 13.4 0.0 8.1 6.3 0.0 2.4 2 0 0 2 2 2 0 NTPase Parvo_NS1 PF01057.17 CBZ28517.1 - 0.075 12.1 0.0 0.5 9.4 0.0 1.9 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 Cytidylate_kin2 PF13189.6 CBZ28517.1 - 0.12 12.5 0.0 0.25 11.5 0.0 1.5 1 0 0 1 1 1 0 Cytidylate kinase-like family ATPase_2 PF01637.18 CBZ28517.1 - 0.13 12.1 0.0 39 4.0 0.0 3.0 2 1 0 3 3 3 0 ATPase domain predominantly from Archaea Guanylate_kin PF00625.21 CBZ28517.1 - 0.16 11.6 0.0 1.3 8.7 0.0 2.1 2 0 0 2 2 2 0 Guanylate kinase Syntaxin PF00804.25 CBZ28518.1 - 1.4e-29 103.3 11.3 1.4e-29 103.3 11.3 1.7 2 0 0 2 2 2 1 Syntaxin SNARE PF05739.19 CBZ28518.1 - 1.8e-09 37.5 0.5 6.6e-09 35.6 0.5 2.0 1 0 0 1 1 1 1 SNARE domain Syntaxin_2 PF14523.6 CBZ28518.1 - 0.0021 18.4 10.2 0.53 10.7 4.2 2.8 2 1 0 2 2 2 2 Syntaxin-like protein Lipoprotein_Ltp PF07553.11 CBZ28518.1 - 0.032 14.5 1.9 6.6 7.1 0.1 2.7 2 0 0 2 2 2 0 Host cell surface-exposed lipoprotein DUF648 PF04890.13 CBZ28518.1 - 0.24 11.1 8.3 7.1 6.3 3.5 2.1 1 1 1 2 2 2 0 Family of unknown function (DUF648) DUF1098 PF06497.11 CBZ28518.1 - 0.25 11.8 3.2 0.57 10.7 0.7 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1098) DUF948 PF06103.11 CBZ28518.1 - 0.39 11.0 7.0 1.8 8.9 1.2 3.0 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) APG6_N PF17675.1 CBZ28518.1 - 2.1 8.9 15.3 0.17 12.4 5.7 2.3 2 1 0 2 2 2 0 Apg6 coiled-coil region DUF423 PF04241.15 CBZ28519.1 - 7.8e-14 51.6 1.3 1.1e-13 51.1 1.0 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF423) NOG1 PF06858.14 CBZ28519.1 - 0.024 14.4 0.0 0.041 13.7 0.0 1.3 1 0 0 1 1 1 0 Nucleolar GTP-binding protein 1 (NOG1) DUF423 PF04241.15 CBZ28520.1 - 1.2e-15 57.5 0.5 1.6e-15 57.1 0.5 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF423) GerA PF03323.13 CBZ28520.1 - 0.095 11.1 0.1 0.14 10.6 0.1 1.1 1 0 0 1 1 1 0 Bacillus/Clostridium GerA spore germination protein DUF423 PF04241.15 CBZ28521.1 - 2.1e-20 72.7 3.3 2.1e-20 72.7 3.3 1.4 2 0 0 2 2 2 1 Protein of unknown function (DUF423) DUF5379 PF17350.2 CBZ28521.1 - 0.049 13.9 0.6 0.21 11.9 0.1 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF5379) DUF3990 PF13151.6 CBZ28523.1 - 2.4 7.8 9.8 1.1 9.0 0.7 3.4 3 1 1 4 4 4 0 Protein of unknown function (DUF3990) DEAD PF00270.29 CBZ28524.1 - 4.7e-43 147.0 0.0 3.3e-42 144.2 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CBZ28524.1 - 3.5e-31 107.8 0.1 2e-30 105.4 0.1 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain CMS1 PF14617.6 CBZ28524.1 - 0.0029 17.0 0.0 0.0069 15.8 0.0 1.6 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit ResIII PF04851.15 CBZ28524.1 - 0.003 17.6 0.0 0.021 14.9 0.0 2.0 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 CBZ28524.1 - 0.018 14.2 0.1 0.026 13.8 0.1 1.2 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase AAA_22 PF13401.6 CBZ28524.1 - 0.093 13.0 0.0 0.55 10.5 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.6 CBZ28524.1 - 0.12 12.7 0.5 0.41 11.0 0.1 2.2 1 1 1 2 2 2 0 AAA domain Coa1 PF08695.10 CBZ28526.1 - 0.02 14.6 0.7 0.035 13.8 0.0 1.7 2 0 0 2 2 2 0 Cytochrome oxidase complex assembly protein 1 DUF2046 PF09755.9 CBZ28527.1 - 0.12 11.6 0.1 0.23 10.7 0.1 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein H4 (DUF2046) Abhydrolase_1 PF00561.20 CBZ28528.1 - 1.1e-17 64.6 0.0 2.1e-14 53.8 0.0 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 CBZ28528.1 - 5.2e-14 52.1 0.0 1.2e-13 50.9 0.0 1.6 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 CBZ28528.1 - 1.8e-10 41.8 0.5 2.2e-10 41.5 0.5 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 CBZ28528.1 - 0.00045 19.7 0.2 0.17 11.4 0.0 3.0 3 1 0 3 3 3 1 Prolyl oligopeptidase family Ndr PF03096.14 CBZ28528.1 - 0.0023 16.7 0.1 0.0056 15.4 0.1 1.6 1 1 0 1 1 1 1 Ndr family Abhydrolase_2 PF02230.16 CBZ28528.1 - 0.018 14.9 0.0 0.16 11.8 0.0 2.1 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase FSH1 PF03959.13 CBZ28528.1 - 0.019 14.6 0.0 0.042 13.5 0.0 1.5 1 0 0 1 1 1 0 Serine hydrolase (FSH1) Peptidase_S15 PF02129.18 CBZ28528.1 - 0.02 14.5 0.0 2.8 7.5 0.0 2.2 2 0 0 2 2 2 0 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_4 PF08386.10 CBZ28528.1 - 0.021 14.9 0.0 0.042 14.0 0.0 1.4 1 0 0 1 1 1 0 TAP-like protein Esterase_phd PF10503.9 CBZ28528.1 - 0.059 12.9 0.6 2.8 7.4 0.1 2.2 2 0 0 2 2 2 0 Esterase PHB depolymerase Esterase PF00756.20 CBZ28528.1 - 0.11 12.1 0.1 0.16 11.6 0.1 1.2 1 0 0 1 1 1 0 Putative esterase TPP_enzyme_N PF02776.18 CBZ28529.1 - 3.4e-13 49.6 1.4 1.5e-12 47.5 0.0 2.2 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.21 CBZ28529.1 - 8e-10 38.7 3.2 1.2e-08 34.9 0.8 3.3 2 1 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Kelch_3 PF13415.6 CBZ28530.1 - 5.5e-14 52.0 6.4 3.7e-06 27.1 0.0 4.5 4 1 1 5 5 5 3 Galactose oxidase, central domain Kelch_4 PF13418.6 CBZ28530.1 - 1.8e-13 50.2 0.2 3.5e-06 26.9 0.0 3.8 3 0 0 3 3 3 3 Galactose oxidase, central domain Kelch_6 PF13964.6 CBZ28530.1 - 7.3e-13 48.3 0.3 2.8e-05 24.2 0.0 4.7 5 0 0 5 5 5 2 Kelch motif Kelch_5 PF13854.6 CBZ28530.1 - 1.6e-11 43.9 0.1 4.4e-05 23.4 0.0 4.5 4 0 0 4 4 4 2 Kelch motif Kelch_2 PF07646.15 CBZ28530.1 - 4.9e-10 39.0 1.5 0.0018 18.2 0.0 4.3 4 0 0 4 4 4 3 Kelch motif Kelch_1 PF01344.25 CBZ28530.1 - 9.2e-10 38.0 1.2 0.00013 21.4 0.0 4.0 3 0 0 3 3 3 2 Kelch motif Helicase_C_2 PF13307.6 CBZ28531.1 - 2.1e-44 151.7 0.0 3.5e-44 151.0 0.0 1.3 1 0 0 1 1 1 1 Helicase C-terminal domain DEAD_2 PF06733.15 CBZ28531.1 - 2.1e-36 125.2 0.0 3.3e-36 124.5 0.0 1.3 1 0 0 1 1 1 1 DEAD_2 ResIII PF04851.15 CBZ28531.1 - 6.9e-05 22.9 0.0 0.051 13.6 0.0 2.4 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit DEAD PF00270.29 CBZ28531.1 - 0.0008 19.2 0.0 0.31 10.8 0.0 2.4 2 0 0 2 2 2 2 DEAD/DEAH box helicase TruD PF01142.18 CBZ28533.1 - 3.9e-30 105.0 0.0 1.6e-26 93.1 0.0 2.9 2 1 0 2 2 2 2 tRNA pseudouridine synthase D (TruD) DUF3342 PF11822.8 CBZ28534.1 - 2.3e-36 123.9 0.0 4.4e-36 123.0 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3342) Pkinase PF00069.25 CBZ28536.1 - 0.015 14.7 0.0 4.6 6.5 0.0 2.3 2 0 0 2 2 2 0 Protein kinase domain Pkinase PF00069.25 CBZ28538.1 - 5.7e-63 212.8 0.0 8.3e-63 212.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ28538.1 - 2.1e-33 115.7 0.0 3.2e-33 115.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Lipocalin_5 PF13924.6 CBZ28538.1 - 1.6e-32 112.2 0.0 3.4e-32 111.2 0.0 1.5 1 0 0 1 1 1 1 Lipocalin-like domain PX PF00787.24 CBZ28538.1 - 2e-14 53.5 0.2 4.4e-14 52.4 0.2 1.5 1 0 0 1 1 1 1 PX domain FYVE PF01363.21 CBZ28538.1 - 9.6e-05 22.4 1.2 0.00027 21.0 1.2 1.8 1 0 0 1 1 1 1 FYVE zinc finger Kinase-like PF14531.6 CBZ28538.1 - 0.00015 21.2 0.0 0.00027 20.4 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 CBZ28538.1 - 0.0005 20.1 3.2 0.0098 15.8 0.3 3.4 2 1 1 3 3 3 1 Phosphotransferase enzyme family Kdo PF06293.14 CBZ28538.1 - 0.062 12.6 0.0 0.14 11.5 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family zf-CRD PF17979.1 CBZ28538.1 - 0.95 9.5 4.5 1 9.4 2.4 2.1 2 0 0 2 2 2 0 Cysteine rich domain with multizinc binding regions Sulfate_transp PF00916.20 CBZ28539.1 - 2.8e-44 151.4 22.1 4.4e-44 150.8 22.1 1.3 1 0 0 1 1 1 1 Sulfate permease family His_Phos_2 PF00328.22 CBZ28539.1 - 1.3e-16 60.9 0.0 2.5e-14 53.4 0.0 2.4 2 0 0 2 2 2 2 Histidine phosphatase superfamily (branch 2) STAS PF01740.21 CBZ28539.1 - 6.1e-08 32.3 0.0 1.2e-07 31.4 0.0 1.4 1 0 0 1 1 1 1 STAS domain DZR PF12773.7 CBZ28540.1 - 0.045 13.8 2.1 0.14 12.2 2.1 1.9 1 0 0 1 1 1 0 Double zinc ribbon zf-HIT PF04438.16 CBZ28540.1 - 0.54 10.2 7.3 1.3 9.0 7.3 1.6 1 0 0 1 1 1 0 HIT zinc finger RPN2_C PF18004.1 CBZ28543.1 - 1.7e-29 102.8 0.0 2.8e-29 102.1 0.0 1.3 1 0 0 1 1 1 1 26S proteasome regulatory subunit RPN2 C-terminal domain HEAT_2 PF13646.6 CBZ28543.1 - 1.3e-16 60.8 4.3 1.3e-11 44.7 0.1 4.6 4 0 0 4 4 4 2 HEAT repeats PC_rep PF01851.22 CBZ28543.1 - 6.7e-16 57.8 8.1 0.17 12.4 0.0 8.1 7 0 0 7 7 7 4 Proteasome/cyclosome repeat Cnd1 PF12717.7 CBZ28543.1 - 0.00053 20.1 0.3 1.2 9.2 0.0 3.0 2 0 0 2 2 2 2 non-SMC mitotic condensation complex subunit 1 TPR_8 PF13181.6 CBZ28543.1 - 0.041 14.1 4.1 76 3.9 0.0 4.9 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_4 PF07721.14 CBZ28543.1 - 0.18 12.5 6.7 4.5 8.2 0.1 5.3 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_2 PF07719.17 CBZ28543.1 - 0.21 11.8 4.6 7.1 7.0 0.0 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.6 CBZ28543.1 - 0.65 11.0 2.9 15 6.7 0.0 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat Methyltr_RsmB-F PF01189.17 CBZ28544.1 - 2.3e-29 102.5 0.4 3.5e-15 56.2 0.3 2.3 2 0 0 2 2 2 2 16S rRNA methyltransferase RsmB/F Methyltransf_24 PF13578.6 CBZ28545.1 - 0.0021 19.1 0.4 0.81 10.7 0.0 2.9 3 0 0 3 3 3 2 Methyltransferase domain Methyltransf_30 PF05430.11 CBZ28545.1 - 0.013 15.4 0.0 0.027 14.4 0.0 1.4 1 0 0 1 1 1 0 S-adenosyl-L-methionine-dependent methyltransferase Pkinase PF00069.25 CBZ28546.1 - 5.4e-13 48.9 0.0 5.3e-12 45.6 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ28546.1 - 0.00035 20.0 0.0 0.00069 19.0 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase WD40 PF00400.32 CBZ28546.1 - 0.0012 19.7 3.1 3.4 8.7 0.1 4.5 4 0 0 4 4 4 2 WD domain, G-beta repeat APH PF01636.23 CBZ28546.1 - 0.0038 17.2 0.0 0.014 15.4 0.0 2.0 1 0 0 1 1 1 1 Phosphotransferase enzyme family PQQ_3 PF13570.6 CBZ28546.1 - 0.51 10.9 7.1 21 5.7 0.0 5.6 5 0 0 5 5 5 0 PQQ-like domain ArfGap PF01412.18 CBZ28547.1 - 1.8e-13 50.6 0.1 2.8e-13 50.0 0.1 1.3 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf Topoisom_bac PF01131.20 CBZ28548.1 - 2.1e-110 369.6 0.0 2.6e-110 369.3 0.0 1.1 1 0 0 1 1 1 1 DNA topoisomerase Toprim PF01751.22 CBZ28548.1 - 1.1e-17 64.1 0.0 1.9e-17 63.3 0.0 1.4 1 0 0 1 1 1 1 Toprim domain AAA PF00004.29 CBZ28549.1 - 3.5e-31 108.4 0.0 5.1e-31 107.8 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 CBZ28549.1 - 2.1e-06 28.1 0.0 4.7e-06 26.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 CBZ28549.1 - 1.1e-05 25.9 0.0 2.1e-05 25.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 CBZ28549.1 - 1.7e-05 25.3 0.0 4.5e-05 23.9 0.0 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_33 PF13671.6 CBZ28549.1 - 3.8e-05 23.9 0.0 7.9e-05 22.8 0.0 1.6 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 CBZ28549.1 - 0.00053 19.8 0.0 0.002 17.9 0.0 1.8 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_28 PF13521.6 CBZ28549.1 - 0.00074 19.8 0.0 0.0014 18.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 CBZ28549.1 - 0.0011 19.3 0.0 0.0038 17.6 0.0 1.9 2 0 0 2 2 2 1 RNA helicase Cytidylate_kin PF02224.18 CBZ28549.1 - 0.0013 18.5 0.1 0.0023 17.7 0.0 1.4 1 1 0 1 1 1 1 Cytidylate kinase RuvB_N PF05496.12 CBZ28549.1 - 0.002 17.9 0.0 0.0048 16.7 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 CBZ28549.1 - 0.0027 17.7 0.0 0.0059 16.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) TsaE PF02367.17 CBZ28549.1 - 0.005 16.8 0.0 0.0093 16.0 0.0 1.3 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_7 PF12775.7 CBZ28549.1 - 0.0059 16.1 0.0 0.013 15.1 0.0 1.5 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_11 PF13086.6 CBZ28549.1 - 0.007 16.2 0.0 0.01 15.6 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 CBZ28549.1 - 0.037 13.7 0.0 0.12 12.1 0.0 1.8 1 1 0 1 1 1 0 AAA domain NACHT PF05729.12 CBZ28549.1 - 0.06 13.3 0.0 0.12 12.3 0.0 1.5 1 0 0 1 1 1 0 NACHT domain AAA_25 PF13481.6 CBZ28549.1 - 0.088 12.4 0.3 1.6 8.3 0.0 2.5 2 1 0 2 2 2 0 AAA domain Rad17 PF03215.15 CBZ28549.1 - 0.096 12.6 0.0 0.2 11.5 0.0 1.5 1 0 0 1 1 1 0 Rad17 P-loop domain KTI12 PF08433.10 CBZ28549.1 - 0.11 11.9 0.0 0.29 10.5 0.0 1.7 2 0 0 2 2 2 0 Chromatin associated protein KTI12 AAA_2 PF07724.14 CBZ28549.1 - 0.12 12.5 0.0 0.48 10.5 0.0 1.9 1 1 0 1 1 1 0 AAA domain (Cdc48 subfamily) AAA_17 PF13207.6 CBZ28549.1 - 0.12 12.8 0.0 0.23 11.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain DnaB_C PF03796.15 CBZ28549.1 - 0.14 11.5 0.0 0.19 11.0 0.0 1.2 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain TIP49 PF06068.13 CBZ28549.1 - 0.14 11.3 0.0 0.21 10.8 0.0 1.1 1 0 0 1 1 1 0 TIP49 P-loop domain PduV-EutP PF10662.9 CBZ28549.1 - 0.16 11.7 0.0 0.5 10.1 0.0 1.8 2 0 0 2 2 1 0 Ethanolamine utilisation - propanediol utilisation DUF2384 PF09722.10 CBZ28550.1 - 0.031 14.3 0.0 0.09 12.8 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2384) TSA PF03249.13 CBZ28551.1 - 0.013 14.3 0.9 0.016 14.0 0.9 1.1 1 0 0 1 1 1 0 Type specific antigen Rep_fac-A_C PF08646.10 CBZ28552.1 - 6.8e-41 139.4 0.7 1.7e-39 134.9 0.2 2.8 3 0 0 3 3 3 1 Replication factor-A C terminal domain REPA_OB_2 PF16900.5 CBZ28552.1 - 2.2e-22 78.8 1.9 1.6e-20 72.9 0.7 2.5 2 0 0 2 2 2 1 Replication protein A OB domain tRNA_anti-codon PF01336.25 CBZ28552.1 - 1.5e-12 47.3 0.5 7.2e-09 35.5 0.0 2.9 3 1 0 3 3 3 2 OB-fold nucleic acid binding domain CDC24_OB3 PF17244.2 CBZ28552.1 - 5e-07 29.7 0.0 2.1e-05 24.4 0.0 2.6 2 1 0 2 2 2 1 Cell division control protein 24, OB domain 3 tRNA_anti_2 PF13742.6 CBZ28552.1 - 0.03 14.5 0.0 0.098 12.9 0.0 1.8 2 0 0 2 2 2 0 OB-fold nucleic acid binding domain DZR PF12773.7 CBZ28552.1 - 0.04 14.0 1.5 0.074 13.1 1.5 1.4 1 0 0 1 1 1 0 Double zinc ribbon zinc-ribbons_6 PF07191.12 CBZ28552.1 - 0.051 13.6 1.0 0.1 12.6 1.0 1.4 1 0 0 1 1 1 0 zinc-ribbons zf_UBZ PF18439.1 CBZ28552.1 - 0.1 12.2 2.5 2.9 7.6 0.3 2.3 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger OrfB_Zn_ribbon PF07282.11 CBZ28552.1 - 0.64 10.0 2.9 1.3 9.0 2.9 1.5 1 0 0 1 1 1 0 Putative transposase DNA-binding domain SNF2_N PF00176.23 CBZ28553.1 - 2.7e-57 194.1 0.0 4.8e-57 193.3 0.0 1.4 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 CBZ28553.1 - 1.6e-11 44.5 0.0 3.6e-11 43.4 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-C3HC4_3 PF13920.6 CBZ28553.1 - 7.4e-10 38.5 9.7 1.9e-09 37.2 9.7 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 CBZ28553.1 - 8.5e-10 38.3 9.8 8.5e-10 38.3 9.8 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 CBZ28553.1 - 8.1e-09 35.2 9.1 2.2e-08 33.8 9.1 1.8 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 CBZ28553.1 - 9.5e-09 35.5 10.6 9.5e-09 35.5 10.6 2.6 2 0 0 2 2 2 1 Ring finger domain zf-RING_UBOX PF13445.6 CBZ28553.1 - 2.5e-08 33.8 6.9 6.2e-08 32.5 6.9 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 CBZ28553.1 - 3.3e-08 33.3 10.6 3.3e-08 33.3 10.6 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CBZ28553.1 - 6.6e-07 29.2 9.3 1.7e-06 27.8 9.3 1.8 1 0 0 1 1 1 1 zinc-RING finger domain ResIII PF04851.15 CBZ28553.1 - 3.5e-06 27.1 0.0 6.6e-06 26.2 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit zf-C3HC4_4 PF15227.6 CBZ28553.1 - 0.0006 19.9 9.1 0.0017 18.5 9.1 1.9 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.7 CBZ28553.1 - 0.0022 18.2 7.3 0.0022 18.2 7.3 2.4 2 0 0 2 2 2 1 RING-H2 zinc finger domain DEAD PF00270.29 CBZ28553.1 - 0.016 15.0 0.0 0.38 10.5 0.0 2.3 2 0 0 2 2 2 0 DEAD/DEAH box helicase zf-RING_11 PF17123.5 CBZ28553.1 - 0.016 14.9 7.5 0.041 13.6 7.5 1.8 1 0 0 1 1 1 0 RING-like zinc finger zf-RING_4 PF14570.6 CBZ28553.1 - 0.16 11.7 7.5 0.38 10.6 7.5 1.7 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING_6 PF14835.6 CBZ28553.1 - 0.21 11.5 3.1 0.58 10.1 3.1 1.7 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-RING_10 PF16685.5 CBZ28553.1 - 1 9.5 9.3 0.18 12.0 5.2 1.9 2 0 0 2 2 1 0 zinc RING finger of MSL2 Aldolase_II PF00596.21 CBZ28554.1 - 6e-42 143.7 0.0 6.8e-42 143.5 0.0 1.0 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain Kinesin PF00225.23 CBZ28555.1 - 2.4e-87 293.0 0.2 3.6e-87 292.4 0.2 1.2 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 CBZ28555.1 - 6.9e-37 126.7 0.0 6.9e-30 104.0 0.0 2.7 2 0 0 2 2 2 2 Microtubule binding bZIP_1 PF00170.21 CBZ28555.1 - 0.14 12.3 3.9 1.3 9.2 0.3 2.6 2 0 0 2 2 2 0 bZIP transcription factor AAA_22 PF13401.6 CBZ28555.1 - 0.29 11.4 1.5 0.77 10.0 0.1 2.5 2 1 0 2 2 2 0 AAA domain DUF4530 PF15039.6 CBZ28555.1 - 0.31 11.2 3.9 18 5.5 1.5 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4530) ZapB PF06005.12 CBZ28555.1 - 0.33 11.4 14.7 1.2 9.7 0.5 3.4 3 0 0 3 3 3 0 Cell division protein ZapB GAS PF13851.6 CBZ28555.1 - 8 5.8 11.5 2.7 7.3 3.9 2.5 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding DUF4586 PF15239.6 CBZ28556.1 - 1.1e-36 127.6 4.1 1.5e-36 127.1 4.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4586) Methyltransf_16 PF10294.9 CBZ28557.1 - 2.5e-14 53.4 0.9 9.2e-11 41.8 0.6 3.2 2 1 0 2 2 2 2 Lysine methyltransferase RIBIOP_C PF04950.12 CBZ28558.1 - 7.4e-75 252.1 0.0 7.4e-75 252.1 0.0 1.7 2 0 0 2 2 1 1 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal AARP2CN PF08142.12 CBZ28558.1 - 9.2e-23 80.1 0.0 4.7e-22 77.9 0.0 2.3 2 0 0 2 2 2 1 AARP2CN (NUC121) domain AAA_22 PF13401.6 CBZ28558.1 - 6.5e-05 23.2 0.0 0.00026 21.3 0.0 2.0 2 0 0 2 2 1 1 AAA domain AAA_16 PF13191.6 CBZ28558.1 - 0.00029 21.2 0.2 0.00094 19.6 0.0 1.9 2 0 0 2 2 1 1 AAA ATPase domain AAA_30 PF13604.6 CBZ28558.1 - 0.00045 20.0 0.4 0.00095 18.9 0.0 1.7 2 0 0 2 2 1 1 AAA domain MMR_HSR1 PF01926.23 CBZ28558.1 - 0.0021 18.1 0.1 0.007 16.4 0.1 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA PF00004.29 CBZ28558.1 - 0.0024 18.3 0.0 0.0067 16.9 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) GTP_EFTU PF00009.27 CBZ28558.1 - 0.0041 16.7 0.0 0.18 11.4 0.0 2.5 1 1 0 2 2 2 1 Elongation factor Tu GTP binding domain ABC_tran PF00005.27 CBZ28558.1 - 0.0092 16.5 0.1 0.06 13.9 0.0 2.3 2 0 0 2 2 2 1 ABC transporter AAA_5 PF07728.14 CBZ28558.1 - 0.02 14.9 0.0 0.086 12.8 0.0 2.1 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_33 PF13671.6 CBZ28558.1 - 0.022 14.9 1.8 0.045 13.9 0.0 2.4 3 0 0 3 3 2 0 AAA domain ATP_bind_1 PF03029.17 CBZ28558.1 - 0.024 14.4 0.0 0.045 13.5 0.0 1.4 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein NTPase_1 PF03266.15 CBZ28558.1 - 0.025 14.5 0.1 0.046 13.6 0.1 1.4 1 0 0 1 1 1 0 NTPase AAA_19 PF13245.6 CBZ28558.1 - 0.026 14.8 0.0 0.06 13.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 CBZ28558.1 - 0.041 14.4 0.4 0.2 12.2 0.0 2.4 2 0 0 2 2 1 0 AAA domain NACHT PF05729.12 CBZ28558.1 - 0.046 13.6 0.0 0.12 12.3 0.0 1.7 1 0 0 1 1 1 0 NACHT domain cobW PF02492.19 CBZ28558.1 - 0.05 13.2 0.0 0.097 12.3 0.0 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain NB-ARC PF00931.22 CBZ28558.1 - 0.054 12.7 0.0 0.092 11.9 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain ATPase_2 PF01637.18 CBZ28558.1 - 0.16 11.8 0.0 0.62 9.9 0.0 1.9 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea Viral_helicase1 PF01443.18 CBZ28558.1 - 0.2 11.4 0.1 0.91 9.2 0.0 2.1 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase AAA_11 PF13086.6 CBZ28558.1 - 0.59 9.9 0.0 0.59 9.9 0.0 3.2 3 0 0 3 3 3 0 AAA domain AAA_23 PF13476.6 CBZ28558.1 - 0.7 10.4 4.4 43 4.5 0.0 3.1 3 0 0 3 3 3 0 AAA domain DHHC PF01529.20 CBZ28559.1 - 1.3e-23 83.5 10.2 1.3e-23 83.5 10.2 2.3 2 0 0 2 2 2 1 DHHC palmitoyltransferase IF-2B PF01008.17 CBZ28559.1 - 0.14 11.4 0.0 0.26 10.4 0.0 1.4 1 0 0 1 1 1 0 Initiation factor 2 subunit family DnaJ PF00226.31 CBZ28560.1 - 1.9e-08 34.3 0.0 3.6e-08 33.4 0.0 1.4 1 0 0 1 1 1 1 DnaJ domain BCIP PF13862.6 CBZ28561.1 - 8.7e-32 110.6 0.0 1.4e-31 109.9 0.0 1.3 1 0 0 1 1 1 1 p21-C-terminal region-binding protein dsDNA_bind PF01984.20 CBZ28562.1 - 1.9e-19 70.0 11.7 2.4e-19 69.7 11.7 1.0 1 0 0 1 1 1 1 Double-stranded DNA-binding domain UPF0154 PF03672.13 CBZ28562.1 - 0.13 12.3 4.3 3 7.9 0.1 3.2 2 1 1 3 3 3 0 Uncharacterised protein family (UPF0154) YlqD PF11068.8 CBZ28562.1 - 0.93 9.9 12.8 0.72 10.2 11.4 1.4 1 1 0 1 1 1 0 YlqD protein DUF1749 PF08538.10 CBZ28562.1 - 1 8.4 4.1 0.75 8.8 0.2 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1749) DUF2870 PF11069.8 CBZ28562.1 - 2.7 8.4 7.3 2.6 8.5 4.7 2.0 1 1 0 2 2 2 0 Protein of unknown function (DUF2870) Zip PF02535.22 CBZ28563.1 - 4.7e-41 141.1 10.6 4.7e-41 141.1 10.6 1.9 2 0 0 2 2 2 1 ZIP Zinc transporter CorA PF01544.18 CBZ28564.1 - 0.011 15.0 3.5 0.011 15.0 3.5 2.2 3 0 0 3 3 3 0 CorA-like Mg2+ transporter protein Peptidase_S15 PF02129.18 CBZ28565.1 - 7.8e-59 199.5 0.0 7.4e-58 196.3 0.1 2.1 2 0 0 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) PepX_C PF08530.10 CBZ28565.1 - 2.9e-32 112.5 0.0 4.2e-32 111.9 0.0 1.2 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain Hydrolase_4 PF12146.8 CBZ28565.1 - 8.6e-09 35.0 0.1 2.6e-07 30.1 0.0 2.2 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 CBZ28565.1 - 7.6e-07 28.8 0.7 5.3e-06 26.1 0.1 2.1 2 0 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 CBZ28565.1 - 8.2e-07 28.9 0.1 1.3e-06 28.3 0.1 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold DLH PF01738.18 CBZ28565.1 - 0.065 12.8 0.0 0.14 11.7 0.0 1.5 1 0 0 1 1 1 0 Dienelactone hydrolase family GTP_EFTU PF00009.27 CBZ28566.1 - 2.7e-43 147.8 0.0 6.4e-43 146.6 0.0 1.7 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_II PF14492.6 CBZ28566.1 - 5.8e-20 71.2 0.0 1.2e-19 70.2 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_C PF00679.24 CBZ28566.1 - 4.8e-12 45.8 0.1 1e-11 44.7 0.1 1.5 1 0 0 1 1 1 1 Elongation factor G C-terminus RF3_C PF16658.5 CBZ28566.1 - 3.1e-06 27.0 0.1 6.8e-06 25.9 0.1 1.5 1 0 0 1 1 1 1 Class II release factor RF3, C-terminal domain GTP_EFTU_D2 PF03144.25 CBZ28566.1 - 7.2e-06 26.3 0.0 2e-05 24.9 0.0 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 CBZ28566.1 - 0.00081 19.5 0.0 0.0019 18.3 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase AIG1 PF04548.16 CBZ28566.1 - 0.014 14.7 0.0 0.028 13.7 0.0 1.4 1 0 0 1 1 1 0 AIG1 family EFG_IV PF03764.18 CBZ28566.1 - 0.015 15.1 0.0 0.09 12.6 0.0 2.2 2 0 0 2 2 2 0 Elongation factor G, domain IV FeoB_N PF02421.18 CBZ28566.1 - 0.042 13.4 0.0 0.15 11.6 0.0 1.8 1 1 0 1 1 1 0 Ferrous iron transport protein B SRPRB PF09439.10 CBZ28566.1 - 0.072 12.5 0.0 0.15 11.5 0.0 1.4 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit LacAB_rpiB PF02502.18 CBZ28567.1 - 1.7e-49 167.4 0.2 2e-49 167.2 0.2 1.1 1 0 0 1 1 1 1 Ribose/Galactose Isomerase Gly_rich_SFCGS PF14272.6 CBZ28567.1 - 0.028 14.5 0.1 0.05 13.6 0.0 1.5 1 1 0 1 1 1 0 Glycine-rich SFCGS LRR_6 PF13516.6 CBZ28569.1 - 2e-14 52.3 4.4 0.029 14.4 0.0 6.6 6 0 0 6 6 6 4 Leucine Rich repeat LRR_4 PF12799.7 CBZ28569.1 - 1.1e-09 38.4 1.9 0.014 15.8 0.0 4.5 4 1 0 4 4 4 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CBZ28569.1 - 0.0009 19.0 10.1 0.27 11.0 0.3 5.0 4 2 0 4 4 4 2 Leucine rich repeat LRR_1 PF00560.33 CBZ28569.1 - 0.002 18.4 1.8 78 4.4 0.0 5.5 5 1 1 6 6 6 0 Leucine Rich Repeat GAS PF13851.6 CBZ28569.1 - 0.13 11.6 0.0 0.3 10.4 0.0 1.5 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding DUF5089 PF17002.5 CBZ28569.1 - 0.31 10.9 1.2 0.41 10.5 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF5089) Sec62 PF03839.16 CBZ28570.1 - 2.4 7.6 6.1 3.2 7.2 6.1 1.1 1 0 0 1 1 1 0 Translocation protein Sec62 DUF4282 PF14110.6 CBZ28570.1 - 2.7 8.8 11.0 7.1 7.4 11.0 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4282) Pkinase PF00069.25 CBZ28571.1 - 1.5e-53 181.9 0.0 3.2e-53 180.8 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ28571.1 - 6.9e-26 91.1 0.0 1e-25 90.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CBZ28571.1 - 1.1e-05 24.5 0.0 2.2e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 CBZ28571.1 - 0.0018 18.2 0.0 0.13 12.2 0.0 2.4 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.6 CBZ28571.1 - 0.0067 15.8 0.0 0.011 15.1 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Choline_kinase PF01633.20 CBZ28571.1 - 0.05 13.2 0.0 0.083 12.5 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase Kdo PF06293.14 CBZ28571.1 - 0.15 11.4 0.2 0.56 9.5 0.1 1.8 1 1 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family D123 PF07065.14 CBZ28572.1 - 0.0075 15.5 0.0 0.013 14.7 0.0 1.4 1 0 0 1 1 1 1 D123 GRIM-19 PF06212.12 CBZ28574.1 - 9.4e-09 35.3 0.2 1.3e-08 34.9 0.2 1.2 1 0 0 1 1 1 1 GRIM-19 protein DPCD PF14913.6 CBZ28575.1 - 2.7e-67 225.8 0.0 3.1e-67 225.6 0.0 1.0 1 0 0 1 1 1 1 DPCD protein family AMP-binding PF00501.28 CBZ28576.1 - 4.4e-31 107.9 0.0 2.3e-30 105.6 0.0 2.0 2 0 0 2 2 2 1 AMP-binding enzyme Ank_4 PF13637.6 CBZ28576.1 - 4.6e-13 49.4 0.8 1.5e-06 28.6 0.1 3.7 2 2 1 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 CBZ28576.1 - 8.6e-12 45.5 2.2 9.3e-05 22.9 0.1 2.8 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 CBZ28576.1 - 2.3e-08 33.7 3.7 1.1 10.0 0.0 5.9 5 0 0 5 5 5 3 Ankyrin repeat Ank_5 PF13857.6 CBZ28576.1 - 3e-07 30.6 6.4 0.03 14.7 0.3 4.5 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.30 CBZ28576.1 - 1.2e-06 28.7 8.5 0.019 15.4 0.1 5.7 5 0 0 5 5 5 1 Ankyrin repeat PP-binding PF00550.25 CBZ28576.1 - 0.0096 16.3 0.0 0.029 14.7 0.0 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site TruB_C PF09142.11 CBZ28576.1 - 0.076 12.8 0.8 0.25 11.1 0.8 1.9 1 0 0 1 1 1 0 tRNA Pseudouridine synthase II, C terminal RNA_pol_L_2 PF13656.6 CBZ28577.1 - 3.4e-23 81.2 0.0 4.9e-23 80.7 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.24 CBZ28577.1 - 0.00022 20.6 0.0 0.00042 19.7 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Sua5_yciO_yrdC PF01300.18 CBZ28578.1 - 1.1e-45 155.3 0.0 1.5e-45 154.9 0.0 1.2 1 0 0 1 1 1 1 Telomere recombination SUA5 PF03481.13 CBZ28578.1 - 1.6e-12 48.2 0.0 2.8e-12 47.4 0.0 1.4 1 0 0 1 1 1 1 Putative GTP-binding controlling metal-binding DEAD PF00270.29 CBZ28579.1 - 1.1e-44 152.4 0.0 4.2e-44 150.4 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CBZ28579.1 - 3e-26 91.9 0.0 1.8e-25 89.4 0.1 2.2 2 1 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 CBZ28579.1 - 2e-05 24.7 0.0 5.4e-05 23.2 0.0 1.7 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 CBZ28579.1 - 0.00055 19.2 0.0 0.00081 18.7 0.0 1.2 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase T4SS-DNA_transf PF02534.14 CBZ28579.1 - 0.016 14.0 0.0 0.024 13.5 0.0 1.2 1 0 0 1 1 1 0 Type IV secretory system Conjugative DNA transfer PhoH PF02562.16 CBZ28579.1 - 0.019 14.4 0.1 5.6 6.4 0.0 2.9 2 1 1 3 3 3 0 PhoH-like protein CEP76-C2 PF15627.6 CBZ28580.1 - 6.7e-39 133.0 0.0 1.2e-38 132.2 0.0 1.4 1 0 0 1 1 1 1 CEP76 C2 domain C2 PF00168.30 CBZ28580.1 - 0.047 14.0 0.0 0.09 13.1 0.0 1.5 1 0 0 1 1 1 0 C2 domain Transglut_core PF01841.19 CBZ28580.1 - 0.12 12.8 0.0 0.49 10.9 0.0 2.0 2 0 0 2 2 2 0 Transglutaminase-like superfamily UPF0220 PF05255.11 CBZ28581.1 - 7.3e-15 54.9 0.7 7.9e-15 54.8 0.7 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0220) PgaD PF13994.6 CBZ28581.1 - 0.03 14.4 0.0 0.058 13.4 0.0 1.4 1 1 0 1 1 1 0 PgaD-like protein YmcE_antitoxin PF15939.5 CBZ28581.1 - 0.13 12.4 0.1 1.1 9.4 0.0 2.2 2 0 0 2 2 2 0 Putative antitoxin of bacterial toxin-antitoxin system LptF_LptG PF03739.14 CBZ28581.1 - 1 8.1 8.0 0.98 8.2 1.3 2.0 2 0 0 2 2 2 0 Lipopolysaccharide export system permease LptF/LptG GDPD PF03009.17 CBZ28582.1 - 1.4e-18 67.5 0.0 1.9e-16 60.6 0.0 2.2 2 0 0 2 2 2 2 Glycerophosphoryl diester phosphodiesterase family PI-PLC-X PF00388.19 CBZ28582.1 - 0.053 13.1 0.0 0.17 11.5 0.0 1.7 2 0 0 2 2 2 0 Phosphatidylinositol-specific phospholipase C, X domain Cullin PF00888.22 CBZ28583.1 - 4e-42 144.7 1.0 4.9e-42 144.4 1.0 1.1 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 CBZ28583.1 - 3e-09 36.8 0.1 2.5e-08 33.8 0.0 2.7 2 0 0 2 2 2 1 Cullin protein neddylation domain TrmB PF01978.19 CBZ28583.1 - 0.014 15.3 0.4 0.26 11.2 0.0 2.7 2 0 0 2 2 2 0 Sugar-specific transcriptional regulator TrmB Penicillinase_R PF03965.16 CBZ28583.1 - 0.028 14.8 0.0 0.13 12.6 0.0 2.1 1 0 0 1 1 1 0 Penicillinase repressor Unstab_antitox PF09720.10 CBZ28583.1 - 0.12 12.4 0.5 0.29 11.2 0.0 1.9 2 0 0 2 2 2 0 Putative addiction module component Pet191_N PF10203.9 CBZ28583.1 - 0.92 9.9 3.2 4.3 7.7 0.1 2.8 3 0 0 3 3 3 0 Cytochrome c oxidase assembly protein PET191 Cullin PF00888.22 CBZ28584.1 - 5.9e-37 127.6 0.0 1.6e-36 126.1 0.0 1.6 1 1 0 1 1 1 1 Cullin family Penicillinase_R PF03965.16 CBZ28584.1 - 0.0012 19.2 0.2 0.0047 17.3 0.1 2.2 2 0 0 2 2 2 1 Penicillinase repressor Cullin_Nedd8 PF10557.9 CBZ28584.1 - 0.0033 17.4 0.0 0.013 15.6 0.0 2.0 1 0 0 1 1 1 1 Cullin protein neddylation domain HTH_20 PF12840.7 CBZ28584.1 - 0.013 15.6 0.3 9.1 6.4 0.2 3.5 4 0 0 4 4 4 0 Helix-turn-helix domain EAP30 PF04157.16 CBZ28584.1 - 0.12 11.7 0.1 0.49 9.6 0.1 1.8 1 1 0 2 2 2 0 EAP30/Vps36 family ANAPC2 PF08672.11 CBZ28584.1 - 0.22 12.1 0.4 1.9 9.1 0.1 2.5 2 0 0 2 2 2 0 Anaphase promoting complex (APC) subunit 2 Dynein_light PF01221.18 CBZ28585.1 - 1.4e-32 111.8 0.0 1.5e-32 111.7 0.0 1.0 1 0 0 1 1 1 1 Dynein light chain type 1 PapC_C PF13953.6 CBZ28585.1 - 0.037 13.8 0.0 0.15 11.9 0.1 1.8 2 0 0 2 2 2 0 PapC C-terminal domain TINF2_N PF14973.6 CBZ28585.1 - 0.048 14.0 0.0 0.056 13.8 0.0 1.1 1 0 0 1 1 1 0 TERF1-interacting nuclear factor 2 N-terminus HhH-GPD PF00730.25 CBZ28586.1 - 9.1e-19 67.9 0.0 2.7e-18 66.4 0.0 1.8 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein NUDIX_4 PF14815.6 CBZ28586.1 - 1.7e-11 44.0 0.0 6.5e-11 42.2 0.0 2.0 2 0 0 2 2 2 1 NUDIX domain HHH PF00633.23 CBZ28586.1 - 1.6e-05 24.5 0.1 5e-05 23.0 0.0 1.9 2 0 0 2 2 2 1 Helix-hairpin-helix motif HHH_2 PF12826.7 CBZ28586.1 - 0.02 15.0 0.0 9.3 6.4 0.0 2.5 2 0 0 2 2 2 0 Helix-hairpin-helix motif HHH_5 PF14520.6 CBZ28586.1 - 0.058 14.0 0.0 1.7 9.3 0.0 2.6 3 0 0 3 3 3 0 Helix-hairpin-helix domain CCB2_CCB4 PF11152.8 CBZ28586.1 - 0.16 11.3 0.0 1.2 8.5 0.0 2.0 2 0 0 2 2 2 0 Cofactor assembly of complex C subunit B, CCB2/CCB4 Kelch_6 PF13964.6 CBZ28587.1 - 5.1e-10 39.3 0.0 0.00023 21.3 0.0 4.1 4 0 0 4 4 4 2 Kelch motif Kelch_3 PF13415.6 CBZ28587.1 - 9.2e-08 32.2 0.8 0.036 14.3 0.0 4.2 4 0 0 4 4 4 2 Galactose oxidase, central domain Kelch_4 PF13418.6 CBZ28587.1 - 6.5e-07 29.3 0.0 0.00047 20.1 0.0 4.0 4 0 0 4 4 4 1 Galactose oxidase, central domain Kelch_5 PF13854.6 CBZ28587.1 - 4.5e-06 26.5 0.0 0.00011 22.1 0.0 2.9 2 0 0 2 2 2 1 Kelch motif Kelch_2 PF07646.15 CBZ28587.1 - 0.00024 20.9 3.0 0.00031 20.6 0.0 2.8 3 0 0 3 3 3 1 Kelch motif Kelch_1 PF01344.25 CBZ28587.1 - 0.0012 18.4 0.1 0.25 11.0 0.0 3.2 3 0 0 3 3 3 1 Kelch motif APS-reductase_C PF12139.8 CBZ28587.1 - 0.0063 16.7 0.0 0.014 15.6 0.0 1.5 1 0 0 1 1 1 1 Adenosine-5'-phosphosulfate reductase beta subunit Methyltransf_25 PF13649.6 CBZ28588.1 - 4.7e-07 30.4 0.0 1e-06 29.3 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 CBZ28588.1 - 8.1e-06 26.4 0.0 2.5e-05 24.8 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 CBZ28588.1 - 2.8e-05 24.8 0.0 4.9e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 CBZ28588.1 - 0.081 12.8 0.0 0.13 12.1 0.0 1.4 1 1 0 1 1 1 0 Methyltransferase domain Sel1 PF08238.12 CBZ28589.1 - 0.093 13.4 6.7 0.96 10.2 0.1 3.7 4 0 0 4 4 4 0 Sel1 repeat ROS_MUCR PF05443.11 CBZ28589.1 - 0.39 10.8 3.3 0.17 11.9 0.3 2.0 2 0 0 2 2 2 0 ROS/MUCR transcriptional regulator protein CorA PF01544.18 CBZ28589.1 - 0.54 9.5 2.1 0.88 8.8 2.1 1.3 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein TipAS PF07739.13 CBZ28589.1 - 0.71 10.4 5.1 15 6.2 1.7 2.7 2 0 0 2 2 2 0 TipAS antibiotic-recognition domain Syntaxin-6_N PF09177.11 CBZ28589.1 - 0.91 10.1 4.2 3 8.5 4.2 1.9 1 0 0 1 1 1 0 Syntaxin 6, N-terminal Prp19 PF08606.11 CBZ28591.1 - 0.021 14.8 1.7 0.034 14.1 0.2 2.2 2 0 0 2 2 2 0 Prp19/Pso4-like SAP30_Sin3_bdg PF13867.6 CBZ28591.1 - 0.083 13.2 0.5 0.17 12.2 0.5 1.4 1 0 0 1 1 1 0 Sin3 binding region of histone deacetylase complex subunit SAP30 dCache_1 PF02743.18 CBZ28591.1 - 0.3 10.9 0.8 0.6 9.8 0.8 1.4 1 0 0 1 1 1 0 Cache domain Sipho_Gp157 PF05565.11 CBZ28591.1 - 0.39 10.7 3.7 0.86 9.6 1.3 2.3 2 0 0 2 2 2 0 Siphovirus Gp157 Ribosomal_60s PF00428.19 CBZ28591.1 - 0.6 10.7 8.0 0.7 10.5 0.2 3.3 2 0 0 2 2 2 0 60s Acidic ribosomal protein TSNAXIP1_N PF15739.5 CBZ28591.1 - 5.9 7.3 8.2 4.2 7.8 1.4 2.7 2 0 0 2 2 2 0 Translin-associated factor X-interacting N-terminus JIP_LZII PF16471.5 CBZ28591.1 - 9.5 6.5 9.4 2.6 8.3 1.1 2.9 2 1 0 2 2 2 0 JNK-interacting protein leucine zipper II Glyco_hydro_63 PF03200.16 CBZ28592.1 - 1e-48 166.4 0.1 2.8e-32 112.1 0.0 2.2 1 1 1 2 2 2 2 Glycosyl hydrolase family 63 C-terminal domain Glyco_hydro_63N PF16923.5 CBZ28592.1 - 1.5e-16 61.2 0.0 3.1e-16 60.1 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 63 N-terminal domain Ribosomal_S14 PF00253.21 CBZ28593.1 - 2.5e-11 43.1 3.5 2.7e-11 43.0 3.5 1.1 1 0 0 1 1 1 1 Ribosomal protein S14p/S29e PhosphMutase PF10143.9 CBZ28595.1 - 5e-45 153.4 0.0 1e-44 152.4 0.0 1.6 1 0 0 1 1 1 1 2,3-bisphosphoglycerate-independent phosphoglycerate mutase Metalloenzyme PF01676.18 CBZ28595.1 - 2.4e-13 50.1 0.0 6.6e-13 48.6 0.0 1.7 1 1 0 1 1 1 1 Metalloenzyme superfamily GGACT PF06094.12 CBZ28595.1 - 9.6e-10 39.1 0.0 2.9e-09 37.6 0.0 1.9 1 0 0 1 1 1 1 Gamma-glutamyl cyclotransferase, AIG2-like Cyclin_N PF00134.23 CBZ28596.1 - 0.00045 20.0 0.1 0.00085 19.1 0.1 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain BCL9 PF11502.8 CBZ28596.1 - 1.5 8.6 7.7 4.3 7.2 7.7 1.8 1 0 0 1 1 1 0 B-cell lymphoma 9 protein PEX11 PF05648.14 CBZ28598.1 - 0.00056 19.4 3.2 0.00092 18.7 3.2 1.4 1 1 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) PEX11 PF05648.14 CBZ28599.1 - 7.5e-19 68.1 2.5 2.1e-18 66.6 2.5 1.6 1 1 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) MOZ_SAS PF01853.18 CBZ28600.1 - 4.5e-40 137.2 0.2 1.2e-21 77.2 0.2 3.5 4 0 0 4 4 4 3 MOZ/SAS family DNA_topoisoIV PF00521.20 CBZ28601.1 - 7.5e-130 433.6 0.0 1.2e-129 433.0 0.0 1.3 1 0 0 1 1 1 1 DNA gyrase/topoisomerase IV, subunit A TOPRIM_C PF16898.5 CBZ28601.1 - 1.3e-42 145.1 0.2 3.9e-42 143.5 0.2 1.9 1 0 0 1 1 1 1 C-terminal associated domain of TOPRIM DNA_gyraseB PF00204.25 CBZ28601.1 - 5.1e-21 74.9 0.1 1.2e-20 73.7 0.1 1.6 1 0 0 1 1 1 1 DNA gyrase B HATPase_c PF02518.26 CBZ28601.1 - 1.1e-09 38.8 0.0 3.3e-09 37.2 0.0 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Toprim PF01751.22 CBZ28601.1 - 0.00032 20.9 0.0 0.0011 19.1 0.0 2.0 1 0 0 1 1 1 1 Toprim domain DNA_gyraseB_C PF00986.21 CBZ28601.1 - 0.016 15.4 0.0 0.041 14.1 0.0 1.8 1 0 0 1 1 1 0 DNA gyrase B subunit, carboxyl terminus Hexapep PF00132.24 CBZ28602.1 - 2.1e-06 27.2 2.3 0.52 10.1 0.0 4.0 1 1 2 3 3 3 3 Bacterial transferase hexapeptide (six repeats) NTP_transferase PF00483.23 CBZ28602.1 - 0.009 15.6 0.0 0.063 12.8 0.0 2.0 2 0 0 2 2 2 1 Nucleotidyl transferase Hexapep_2 PF14602.6 CBZ28602.1 - 0.018 14.8 4.6 0.16 11.8 0.2 3.4 1 1 2 3 3 3 0 Hexapeptide repeat of succinyl-transferase DUF4954 PF16314.5 CBZ28602.1 - 0.032 12.4 0.0 0.046 11.9 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4954) Cep57_MT_bd PF06657.13 CBZ28603.1 - 0.056 13.9 9.9 0.09 13.2 0.0 3.6 3 1 0 3 3 3 0 Centrosome microtubule-binding domain of Cep57 Glutaminase PF04960.15 CBZ28603.1 - 0.15 11.3 0.0 0.76 8.9 0.0 2.0 2 0 0 2 2 2 0 Glutaminase CENP-H PF05837.12 CBZ28603.1 - 1.7 9.1 18.0 0.18 12.3 0.3 3.2 2 1 1 3 3 3 0 Centromere protein H (CENP-H) BCAS2 PF05700.11 CBZ28603.1 - 2.1 8.0 13.4 0.31 10.7 0.7 3.3 1 1 2 3 3 3 0 Breast carcinoma amplified sequence 2 (BCAS2) UPF0184 PF03670.13 CBZ28603.1 - 4.4 7.8 5.8 2 8.9 1.4 2.4 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0184) eIF3_N PF09440.10 CBZ28604.1 - 9.9e-12 45.4 2.6 2.6e-11 44.1 2.6 1.8 1 0 0 1 1 1 1 eIF3 subunit 6 N terminal domain PCI PF01399.27 CBZ28604.1 - 5.4e-10 39.7 0.5 1.8e-09 38.0 0.3 2.0 2 0 0 2 2 2 1 PCI domain TPR_3 PF07720.12 CBZ28604.1 - 0.068 13.2 1.5 0.18 11.9 1.5 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat CactinC_cactus PF09732.9 CBZ28606.1 - 1e-37 128.9 2.2 2e-37 127.9 2.2 1.4 1 0 0 1 1 1 1 Cactus-binding C-terminus of cactin protein SHMT PF00464.19 CBZ28609.1 - 2.6e-173 576.2 0.0 3.3e-173 575.9 0.0 1.1 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Beta_elim_lyase PF01212.21 CBZ28609.1 - 0.037 13.3 0.0 0.061 12.6 0.0 1.4 1 0 0 1 1 1 0 Beta-eliminating lyase Laminin_EGF PF00053.24 CBZ28610.1 - 0.0032 17.6 12.9 0.0032 17.6 12.9 7.9 4 3 3 7 7 7 4 Laminin EGF domain EGF_2 PF07974.13 CBZ28610.1 - 0.007 16.7 15.7 0.007 16.7 15.7 10.2 11 2 1 12 12 12 3 EGF-like domain MCM PF00493.23 CBZ28611.1 - 7.1e-92 306.5 0.3 1e-91 306.0 0.3 1.3 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 CBZ28611.1 - 5.1e-35 120.1 0.8 9.1e-35 119.3 0.8 1.4 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 CBZ28611.1 - 1.5e-21 76.6 4.6 2.5e-21 75.9 3.3 2.2 3 0 0 3 3 3 1 MCM AAA-lid domain MCM6_C PF18263.1 CBZ28611.1 - 9.1e-09 35.5 0.0 2e-08 34.4 0.0 1.5 1 0 0 1 1 1 1 MCM6 C-terminal winged-helix domain Mg_chelatase PF01078.21 CBZ28611.1 - 6.6e-07 28.9 0.0 3.7e-06 26.5 0.0 2.1 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 CBZ28611.1 - 0.00046 20.2 0.1 0.0031 17.5 0.0 2.3 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) MCM_N PF14551.6 CBZ28611.1 - 0.0026 18.3 0.0 0.0068 17.0 0.0 1.7 1 0 0 1 1 1 1 MCM N-terminal domain AAA_3 PF07726.11 CBZ28611.1 - 0.0058 16.5 0.0 0.016 15.0 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 CBZ28611.1 - 0.0079 15.9 0.0 0.021 14.6 0.0 1.7 1 0 0 1 1 1 1 Sigma-54 interaction domain AadA_C PF18280.1 CBZ28611.1 - 0.061 13.5 0.1 0.82 9.8 0.0 2.8 3 0 0 3 3 3 0 Aminoglycoside adenyltransferase C-terminal domain DUF188 PF02639.14 CBZ28611.1 - 0.21 11.2 1.0 13 5.4 0.1 2.6 2 0 0 2 2 2 0 Uncharacterized BCR, YaiI/YqxD family COG1671 WW PF00397.26 CBZ28612.1 - 3.8e-09 36.5 0.9 7.8e-09 35.5 0.9 1.6 1 0 0 1 1 1 1 WW domain GCD14 PF08704.10 CBZ28613.1 - 5.6e-63 212.9 1.1 9e-37 127.1 0.0 3.7 2 1 2 4 4 4 2 tRNA methyltransferase complex GCD14 subunit Methyltransf_31 PF13847.6 CBZ28613.1 - 1.5e-07 31.3 0.0 3.6e-07 30.1 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CBZ28613.1 - 3e-06 27.8 0.1 0.00033 21.3 0.1 2.7 1 1 0 1 1 1 1 Methyltransferase domain GCD14_N PF14801.6 CBZ28613.1 - 2.3e-05 24.2 0.2 5.6e-05 22.9 0.1 1.8 1 1 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit N-term PCMT PF01135.19 CBZ28613.1 - 6.1e-05 22.9 0.0 0.0002 21.2 0.0 1.9 1 1 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Fibrillarin PF01269.17 CBZ28613.1 - 0.00062 19.0 0.0 0.21 10.7 0.0 2.3 2 0 0 2 2 2 2 Fibrillarin Methyltransf_24 PF13578.6 CBZ28613.1 - 0.0021 19.1 0.1 0.0057 17.7 0.1 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CBZ28613.1 - 0.0034 18.0 0.1 0.025 15.2 0.1 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CBZ28613.1 - 0.0057 17.4 0.0 0.084 13.6 0.0 2.5 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 CBZ28613.1 - 0.029 13.7 0.0 0.32 10.3 0.0 2.0 2 0 0 2 2 2 0 ubiE/COQ5 methyltransferase family RrnaAD PF00398.20 CBZ28613.1 - 0.08 12.0 0.0 0.13 11.3 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase MTS PF05175.14 CBZ28613.1 - 0.12 11.9 0.1 0.46 10.0 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase small domain Rft-1 PF04506.13 CBZ28614.1 - 5.6e-47 160.6 7.3 1.4e-40 139.6 4.4 2.3 2 1 0 2 2 2 2 Rft protein Herpes_ICP4_N PF03584.15 CBZ28614.1 - 0.0059 16.5 0.3 0.03 14.2 0.1 2.0 2 0 0 2 2 2 1 Herpesvirus ICP4-like protein N-terminal region 2-oxoacid_dh PF00198.23 CBZ28615.1 - 3.6e-80 268.8 0.3 4.6e-80 268.4 0.3 1.1 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 CBZ28615.1 - 1.9e-19 69.2 1.5 3.2e-19 68.5 1.5 1.4 1 0 0 1 1 1 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.6 CBZ28615.1 - 1.7e-05 24.5 0.5 0.093 12.6 0.1 2.4 1 1 1 2 2 2 2 Biotin-lipoyl like GCV_H PF01597.19 CBZ28615.1 - 0.0017 18.2 0.4 0.0032 17.3 0.4 1.4 1 0 0 1 1 1 1 Glycine cleavage H-protein RnfC_N PF13375.6 CBZ28615.1 - 0.025 14.5 0.1 0.052 13.5 0.1 1.5 1 0 0 1 1 1 0 RnfC Barrel sandwich hybrid domain HlyD_D23 PF16576.5 CBZ28615.1 - 0.1 11.8 0.1 0.74 9.0 0.0 2.0 1 1 1 2 2 2 0 Barrel-sandwich domain of CusB or HlyD membrane-fusion ATP-synt_ab PF00006.25 CBZ28616.1 - 4.3e-67 225.9 0.0 5.6e-67 225.5 0.0 1.1 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N PF02874.23 CBZ28616.1 - 3.6e-14 53.0 0.7 7.1e-14 52.1 0.7 1.5 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain NTP_transferase PF00483.23 CBZ28617.1 - 0.00051 19.7 0.0 0.0013 18.4 0.0 1.6 2 0 0 2 2 2 1 Nucleotidyl transferase Fucokinase PF07959.12 CBZ28617.1 - 0.0044 16.0 0.2 0.0074 15.3 0.2 1.3 1 0 0 1 1 1 1 L-fucokinase Hexapep PF00132.24 CBZ28617.1 - 0.0047 16.6 14.5 0.55 10.1 5.3 3.7 1 1 2 3 3 3 2 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.7 CBZ28617.1 - 0.028 14.8 0.0 0.25 11.7 0.0 2.3 1 1 0 1 1 1 0 MobA-like NTP transferase domain DUF4954 PF16314.5 CBZ28617.1 - 0.1 10.7 2.1 0.36 8.9 1.9 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4954) DUF676 PF05057.14 CBZ28618.1 - 1.4e-14 54.1 0.0 1.5e-13 50.7 0.0 2.4 1 1 0 1 1 1 1 Putative serine esterase (DUF676) Palm_thioest PF02089.15 CBZ28618.1 - 0.0089 15.9 0.0 0.022 14.6 0.0 1.4 1 1 0 1 1 1 1 Palmitoyl protein thioesterase DUF3682 PF12446.8 CBZ28618.1 - 0.089 13.3 1.2 0.18 12.3 1.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3682) VCBS PF13517.6 CBZ28619.1 - 9.4e-06 26.1 0.0 2.3 8.9 0.0 4.9 4 0 0 4 4 4 2 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FG-GAP PF01839.23 CBZ28619.1 - 4.1e-05 23.6 0.2 0.013 15.6 0.0 3.6 3 0 0 3 3 3 1 FG-GAP repeat TcdB_toxin_midN PF12256.8 CBZ28619.1 - 0.0087 15.4 0.6 0.48 9.8 0.0 2.9 3 0 0 3 3 3 1 Insecticide toxin TcdB middle/N-terminal region Ribosomal_S14 PF00253.21 CBZ28620.1 - 2.5e-11 43.1 3.5 2.7e-11 43.0 3.5 1.1 1 0 0 1 1 1 1 Ribosomal protein S14p/S29e ParA PF10609.9 CBZ28621.1 - 4.5e-91 304.7 0.0 5.2e-91 304.5 0.0 1.0 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 CBZ28621.1 - 3.3e-15 56.3 0.0 6.5e-15 55.3 0.0 1.5 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.6 CBZ28621.1 - 7.5e-12 45.5 1.1 1.6e-09 37.9 0.1 2.1 2 0 0 2 2 2 2 AAA domain MipZ PF09140.11 CBZ28621.1 - 1.7e-08 34.1 1.2 9.8e-08 31.6 1.2 1.9 1 1 0 1 1 1 1 ATPase MipZ Fer4_NifH PF00142.18 CBZ28621.1 - 3.5e-05 23.4 0.0 0.00041 19.9 0.1 2.1 2 0 0 2 2 2 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family VirC1 PF07015.11 CBZ28621.1 - 5.9e-05 22.5 0.2 0.00013 21.4 0.1 1.5 2 0 0 2 2 2 1 VirC1 protein ArsA_ATPase PF02374.15 CBZ28621.1 - 0.00026 20.3 0.7 0.0017 17.6 0.6 2.0 2 0 0 2 2 2 1 Anion-transporting ATPase CBP_BcsQ PF06564.12 CBZ28621.1 - 0.0078 15.7 0.0 0.019 14.4 0.0 1.6 1 1 0 1 1 1 1 Cellulose biosynthesis protein BcsQ DUF1611 PF07755.11 CBZ28621.1 - 0.053 12.8 1.4 0.18 11.1 0.3 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF1611_C) P-loop domain AAA_26 PF13500.6 CBZ28621.1 - 0.15 11.8 0.4 14 5.5 0.0 2.2 2 0 0 2 2 2 0 AAA domain Sensor PF13796.6 CBZ28622.1 - 0.072 13.1 1.5 0.48 10.5 0.0 2.4 2 0 0 2 2 2 0 Putative sensor Myc_N PF01056.18 CBZ28623.1 - 0.86 9.4 7.2 9.3 6.0 0.2 2.2 2 0 0 2 2 2 0 Myc amino-terminal region IF4E PF01652.18 CBZ28624.1 - 3.2e-30 105.0 0.0 4.4e-30 104.6 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E Acyl-CoA_dh_C PF12806.7 CBZ28625.1 - 3.4e-23 82.1 1.0 3.4e-23 82.1 1.0 1.7 2 0 0 2 2 2 1 Acetyl-CoA dehydrogenase C-terminal like Acyl-CoA_dh_M PF02770.19 CBZ28625.1 - 2.3e-19 69.4 0.0 5.6e-19 68.1 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.24 CBZ28625.1 - 4.4e-19 69.2 3.6 5.1e-18 65.7 3.6 2.5 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 CBZ28625.1 - 8.4e-12 45.8 0.0 2e-11 44.6 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 CBZ28625.1 - 1.7e-05 25.1 0.0 1.7e-05 25.1 0.0 1.9 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain R3H PF01424.22 CBZ28626.1 - 6.9e-11 42.0 0.4 1.5e-10 40.9 0.4 1.6 1 0 0 1 1 1 1 R3H domain ABC_trans_N PF14510.6 CBZ28626.1 - 0.16 12.6 2.9 2.6 8.7 0.0 3.5 3 0 0 3 3 3 0 ABC-transporter N-terminal LPP20 PF02169.16 CBZ28626.1 - 0.18 12.2 3.5 0.88 10.0 2.0 2.4 2 0 0 2 2 2 0 LPP20 lipoprotein NUDE_C PF04880.13 CBZ28626.1 - 1.7 9.1 11.6 0.095 13.2 2.6 2.5 2 0 0 2 2 2 0 NUDE protein, C-terminal conserved region PIF1 PF05970.14 CBZ28627.1 - 5.7e-29 101.4 0.0 1.3e-25 90.4 0.0 2.6 3 0 0 3 3 3 2 PIF1-like helicase AAA_30 PF13604.6 CBZ28627.1 - 2.9e-16 59.8 0.3 8.5e-16 58.2 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 CBZ28627.1 - 3e-06 27.6 0.1 9.9e-06 26.0 0.1 1.9 1 1 0 1 1 1 1 AAA domain UvrD_C_2 PF13538.6 CBZ28627.1 - 2.2e-05 24.2 0.1 5.2e-05 23.0 0.1 1.7 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain Viral_helicase1 PF01443.18 CBZ28627.1 - 0.00026 20.8 0.0 0.71 9.6 0.0 2.6 2 0 0 2 2 2 2 Viral (Superfamily 1) RNA helicase MobB PF03205.14 CBZ28627.1 - 0.063 13.2 0.1 0.13 12.2 0.1 1.4 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Herpes_Helicase PF02689.14 CBZ28627.1 - 0.072 11.0 0.2 6.1 4.6 0.0 2.3 2 0 0 2 2 2 0 Helicase NTPase_1 PF03266.15 CBZ28627.1 - 0.097 12.6 0.7 0.76 9.7 0.2 2.2 2 0 0 2 2 2 0 NTPase AAA PF00004.29 CBZ28627.1 - 0.12 12.7 0.0 0.46 10.9 0.0 2.0 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) THOC2_N PF16134.5 CBZ28627.1 - 0.15 10.6 0.2 0.22 10.1 0.2 1.1 1 0 0 1 1 1 0 THO complex subunit 2 N-terminus AAA_16 PF13191.6 CBZ28627.1 - 0.17 12.3 2.7 0.27 11.6 0.0 2.6 3 0 0 3 3 3 0 AAA ATPase domain DUF2075 PF09848.9 CBZ28627.1 - 0.18 11.0 0.6 0.54 9.4 0.6 1.8 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_22 PF13401.6 CBZ28627.1 - 0.32 11.3 1.5 7.2 6.9 1.5 2.6 1 1 0 1 1 1 0 AAA domain AAA_11 PF13086.6 CBZ28627.1 - 2.1 8.1 4.7 8 6.2 0.0 2.9 2 1 1 3 3 3 0 AAA domain DUF853 PF05872.12 CBZ28627.1 - 2.8 6.4 7.8 0.22 10.1 0.1 2.3 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF853) DUF3584 PF12128.8 CBZ28627.1 - 6.2 4.2 6.4 9.4 3.6 6.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) HEAT_2 PF13646.6 CBZ28628.1 - 9.4e-09 35.6 19.2 1.2e-05 25.6 1.4 6.3 6 1 1 7 7 7 2 HEAT repeats HEAT PF02985.22 CBZ28628.1 - 7.9e-06 25.7 10.6 0.033 14.4 0.0 6.3 7 0 0 7 7 7 3 HEAT repeat IFRD PF05004.13 CBZ28628.1 - 0.00047 19.4 1.1 0.0019 17.4 0.4 2.1 2 0 0 2 2 2 1 Interferon-related developmental regulator (IFRD) TPR_2 PF07719.17 CBZ28629.1 - 3.3e-05 23.7 0.1 0.11 12.6 0.2 2.9 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.6 CBZ28629.1 - 0.00033 20.9 0.1 1.2 9.5 0.1 3.1 2 0 0 2 2 2 2 Tetratricopeptide repeat SET PF00856.28 CBZ28629.1 - 0.0012 19.3 0.0 0.0031 17.9 0.0 1.7 1 0 0 1 1 1 1 SET domain zf-MYND PF01753.18 CBZ28629.1 - 0.0016 18.5 6.6 0.0016 18.5 6.6 2.5 2 0 0 2 2 2 1 MYND finger Zn-ribbon_8 PF09723.10 CBZ28629.1 - 0.0039 17.3 0.3 0.012 15.7 0.3 1.9 1 0 0 1 1 1 1 Zinc ribbon domain Ribosomal_S17e PF00833.18 CBZ28630.1 - 3e-50 169.2 3.9 3.7e-50 168.9 3.9 1.1 1 0 0 1 1 1 1 Ribosomal S17 Ribosomal_S17e PF00833.18 CBZ28631.1 - 3e-50 169.2 3.9 3.7e-50 168.9 3.9 1.1 1 0 0 1 1 1 1 Ribosomal S17 SF3b1 PF08920.10 CBZ28633.1 - 4.6e-07 30.3 0.1 1.1e-06 29.1 0.1 1.6 1 0 0 1 1 1 1 Splicing factor 3B subunit 1 HEAT_2 PF13646.6 CBZ28633.1 - 7.1e-07 29.5 19.8 0.028 14.8 4.7 7.0 5 2 2 7 7 7 2 HEAT repeats UME PF08064.13 CBZ28633.1 - 4.3e-05 23.4 1.2 0.0035 17.2 0.1 3.8 4 0 0 4 4 4 1 UME (NUC010) domain DRIM PF07539.12 CBZ28633.1 - 0.0072 14.7 2.7 0.47 8.7 1.2 2.6 2 0 0 2 2 2 2 Down-regulated in metastasis NUC173 PF08161.12 CBZ28633.1 - 0.014 15.0 2.9 2.8 7.5 0.0 4.4 4 2 0 4 4 4 0 NUC173 domain Adaptin_N PF01602.20 CBZ28633.1 - 0.025 13.1 1.1 4.1 5.8 0.1 2.7 1 1 0 2 2 2 0 Adaptin N terminal region CTD PF12815.7 CBZ28633.1 - 0.077 13.6 3.6 0.16 12.5 3.6 1.5 1 0 0 1 1 1 0 Spt5 C-terminal nonapeptide repeat binding Spt4 DHO_dh PF01180.21 CBZ28633.1 - 0.1 11.8 0.1 0.19 10.9 0.1 1.4 1 0 0 1 1 1 0 Dihydroorotate dehydrogenase Cnd1 PF12717.7 CBZ28633.1 - 0.76 9.8 8.0 2.2 8.3 0.5 4.2 4 1 0 4 4 4 0 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 CBZ28633.1 - 1.9 9.0 17.4 7.8 7.1 0.0 7.0 7 0 0 7 7 7 0 HEAT repeat HEAT_EZ PF13513.6 CBZ28633.1 - 2 9.0 22.3 11 6.6 0.0 7.7 7 2 2 9 9 8 0 HEAT-like repeat LRR_4 PF12799.7 CBZ28634.1 - 1.8e-10 40.8 6.4 0.00076 19.8 0.0 4.3 2 2 2 4 4 4 3 Leucine Rich repeats (2 copies) IQ PF00612.27 CBZ28634.1 - 4.8e-10 38.3 9.9 1.1e-05 24.7 2.5 2.8 2 0 0 2 2 2 2 IQ calmodulin-binding motif LRR_8 PF13855.6 CBZ28634.1 - 2.3e-06 27.3 13.5 0.0017 18.1 0.2 4.1 2 2 2 4 4 4 4 Leucine rich repeat LRR_9 PF14580.6 CBZ28634.1 - 0.0019 17.8 1.0 0.037 13.5 0.3 2.5 2 0 0 2 2 2 1 Leucine-rich repeat LRR_1 PF00560.33 CBZ28634.1 - 0.014 15.8 4.8 19 6.3 0.0 5.0 5 0 0 5 5 5 0 Leucine Rich Repeat LRR_6 PF13516.6 CBZ28634.1 - 1.2 9.4 10.6 40 4.6 0.2 5.4 7 0 0 7 7 7 0 Leucine Rich repeat ADP_ribosyl_GH PF03747.14 CBZ28635.1 - 6e-11 42.6 0.6 1e-06 28.7 0.3 2.5 1 1 1 2 2 2 2 ADP-ribosylglycohydrolase IQ PF00612.27 CBZ28636.1 - 2.4e-21 73.5 94.5 6.3e-05 22.4 2.1 14.3 14 0 0 14 14 14 8 IQ calmodulin-binding motif Fis1_TPR_C PF14853.6 CBZ28636.1 - 0.012 15.6 0.1 0.032 14.3 0.1 1.6 1 0 0 1 1 1 0 Fis1 C-terminal tetratricopeptide repeat TPR_1 PF00515.28 CBZ28636.1 - 0.25 11.2 2.8 0.19 11.6 0.2 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.6 CBZ28636.1 - 2.4 9.0 4.6 5.8 7.8 0.3 4.0 2 0 0 2 2 2 0 Tetratricopeptide repeat Adaptin_N PF01602.20 CBZ28637.1 - 2.7e-71 240.7 10.6 3.4e-71 240.4 10.6 1.1 1 0 0 1 1 1 1 Adaptin N terminal region COP-gamma_platf PF08752.10 CBZ28637.1 - 7.6e-34 117.0 1.2 1.5e-33 116.1 0.3 1.9 2 0 0 2 2 2 1 Coatomer gamma subunit appendage platform subdomain Coatomer_g_Cpla PF16381.5 CBZ28637.1 - 2.7e-21 75.8 0.0 5.7e-21 74.8 0.0 1.6 1 0 0 1 1 1 1 Coatomer subunit gamma-1 C-terminal appendage platform HEAT_2 PF13646.6 CBZ28637.1 - 1.1e-11 44.9 0.1 1.6e-05 25.2 0.0 4.6 3 1 1 4 4 4 2 HEAT repeats HEAT PF02985.22 CBZ28637.1 - 2.3e-05 24.3 4.4 11 6.6 0.0 6.0 6 0 0 6 6 6 3 HEAT repeat Cnd1 PF12717.7 CBZ28637.1 - 8.3e-05 22.7 9.7 0.0038 17.3 0.8 4.2 3 1 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 DUF1719 PF08224.11 CBZ28637.1 - 0.13 11.3 0.8 0.26 10.4 0.1 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF1719) MoaC PF01967.21 CBZ28639.1 - 2.7e-22 79.3 0.6 7.8e-22 77.8 0.0 2.1 3 0 0 3 3 3 1 MoaC family His_Phos_2 PF00328.22 CBZ28640.1 - 7.9e-10 38.6 0.4 4e-07 29.7 0.0 2.4 1 1 1 2 2 2 2 Histidine phosphatase superfamily (branch 2) SelR PF01641.18 CBZ28641.1 - 1.6e-39 134.7 0.0 1.9e-39 134.5 0.0 1.1 1 0 0 1 1 1 1 SelR domain zinc_ribbon_10 PF10058.9 CBZ28641.1 - 0.001 18.7 0.1 0.11 12.3 0.0 2.4 2 0 0 2 2 2 1 Predicted integral membrane zinc-ribbon metal-binding protein FYVE PF01363.21 CBZ28641.1 - 0.024 14.8 1.1 0.044 13.9 1.1 1.4 1 0 0 1 1 1 0 FYVE zinc finger Yippee-Mis18 PF03226.14 CBZ28641.1 - 0.031 14.5 1.1 0.33 11.2 1.1 2.2 1 1 0 1 1 1 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly DUF4796 PF16044.5 CBZ28641.1 - 0.035 13.7 0.1 0.065 12.8 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4796) zf_C2HC_14 PF18574.1 CBZ28641.1 - 0.046 13.5 0.9 0.099 12.5 0.1 2.0 2 0 0 2 2 2 0 C2HC Zing finger domain TF_Zn_Ribbon PF08271.12 CBZ28641.1 - 0.12 11.9 3.9 0.52 9.9 0.2 2.8 3 0 0 3 3 3 0 TFIIB zinc-binding Metallophos PF00149.28 CBZ28642.1 - 9.5e-34 117.7 0.1 1.2e-33 117.3 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase zf_UBZ PF18439.1 CBZ28642.1 - 0.11 12.1 0.1 12 5.6 0.0 2.4 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger VitD-bind_III PF09164.10 CBZ28642.1 - 0.11 12.5 0.7 0.27 11.3 0.7 1.6 1 0 0 1 1 1 0 Vitamin D binding protein, domain III COX15-CtaA PF02628.15 CBZ28643.1 - 4.1e-103 344.9 11.7 4.8e-103 344.6 11.7 1.0 1 0 0 1 1 1 1 Cytochrome oxidase assembly protein 2OG-FeII_Oxy_2 PF13532.6 CBZ28646.1 - 0.00014 22.1 0.0 0.00022 21.5 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DNA_processg_A PF02481.15 CBZ28647.1 - 0.03 13.6 0.1 0.038 13.2 0.1 1.1 1 0 0 1 1 1 0 DNA recombination-mediator protein A CBS PF00571.28 CBZ28647.1 - 0.043 14.3 0.0 0.78 10.2 0.0 2.1 2 0 0 2 2 2 0 CBS domain APG12 PF04110.13 CBZ28647.1 - 0.059 13.8 0.0 0.44 11.0 0.0 2.0 2 0 0 2 2 2 0 Ubiquitin-like autophagy protein Apg12 DUF179 PF02622.15 CBZ28648.1 - 6.7e-06 26.1 0.0 1.3e-05 25.2 0.0 1.5 1 0 0 1 1 1 1 Uncharacterized ACR, COG1678 WD40 PF00400.32 CBZ28649.1 - 1.4e-45 152.3 19.5 3.2e-08 34.1 0.0 7.1 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBZ28649.1 - 7.7e-13 48.6 0.3 0.011 16.1 0.0 4.1 1 1 4 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 CBZ28649.1 - 2.6e-09 36.3 3.1 0.016 13.9 0.2 3.9 1 1 3 4 4 4 3 Nucleoporin Nup120/160 eIF2A PF08662.11 CBZ28649.1 - 2.4e-07 30.8 0.0 0.00031 20.7 0.0 2.7 1 1 2 3 3 3 3 Eukaryotic translation initiation factor eIF2A PD40 PF07676.12 CBZ28649.1 - 6.7e-05 22.7 0.0 1.8 8.6 0.0 4.7 5 0 0 5 5 5 1 WD40-like Beta Propeller Repeat Ge1_WD40 PF16529.5 CBZ28649.1 - 0.00028 20.0 1.5 0.029 13.3 0.8 3.5 1 1 2 4 4 4 1 WD40 region of Ge1, enhancer of mRNA-decapping protein PQQ_2 PF13360.6 CBZ28649.1 - 0.0013 18.3 0.0 0.12 11.9 0.0 1.9 1 1 1 2 2 2 2 PQQ-like domain WD40_like PF17005.5 CBZ28649.1 - 0.0068 15.8 0.0 0.0091 15.3 0.0 1.3 1 0 0 1 1 1 1 WD40-like domain Cytochrom_D1 PF02239.16 CBZ28649.1 - 0.048 12.2 0.0 1.2 7.6 0.0 2.3 2 0 0 2 2 2 0 Cytochrome D1 heme domain Coatomer_WDAD PF04053.14 CBZ28649.1 - 0.21 10.6 0.0 0.56 9.2 0.0 1.5 1 1 1 2 2 2 0 Coatomer WD associated region GCP_C_terminal PF04130.13 CBZ28650.1 - 1.2e-40 139.9 9.3 2.2e-40 139.0 9.3 1.5 1 0 0 1 1 1 1 Gamma tubulin complex component C-terminal GCP_N_terminal PF17681.1 CBZ28650.1 - 1.1e-32 113.9 0.3 3.7e-32 112.2 0.0 1.9 2 0 0 2 2 2 1 Gamma tubulin complex component N-terminal HSP70 PF00012.20 CBZ28651.1 - 1.1e-261 869.4 5.3 1.2e-261 869.2 5.3 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 CBZ28651.1 - 8.9e-14 51.0 0.0 1.3e-12 47.2 0.0 2.1 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.16 CBZ28651.1 - 0.043 13.5 0.1 0.11 12.2 0.0 1.7 2 0 0 2 2 2 0 FGGY family of carbohydrate kinases, C-terminal domain DUF4364 PF14277.6 CBZ28651.1 - 0.077 12.7 1.5 0.22 11.3 1.5 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4364) DDR PF08841.10 CBZ28651.1 - 0.079 11.9 0.6 2.1 7.3 0.2 2.2 2 0 0 2 2 2 0 Diol dehydratase reactivase ATPase-like domain DUF5581 PF17744.1 CBZ28651.1 - 0.1 12.0 0.2 11 5.3 0.0 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5581) DUF2508 PF10704.9 CBZ28651.1 - 0.24 11.6 2.9 2.7 8.2 0.4 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2508) HSP70 PF00012.20 CBZ28652.1 - 6e-103 345.1 0.4 6.8e-103 344.9 0.4 1.0 1 0 0 1 1 1 1 Hsp70 protein DUF4364 PF14277.6 CBZ28652.1 - 0.059 13.1 2.4 0.079 12.7 1.8 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4364) Jnk-SapK_ap_N PF09744.9 CBZ28653.1 - 0.53 10.5 8.7 0.37 11.0 2.7 3.1 3 1 0 3 3 3 0 JNK_SAPK-associated protein-1 HALZ PF02183.18 CBZ28653.1 - 0.95 9.7 13.4 1.1 9.6 0.5 3.2 3 0 0 3 3 3 0 Homeobox associated leucine zipper Beta-lactamase PF00144.24 CBZ28654.1 - 3.5e-10 39.7 0.1 1e-09 38.1 0.1 1.6 1 1 0 1 1 1 1 Beta-lactamase FlgT_N PF16548.5 CBZ28655.1 - 0.042 14.4 0.2 0.083 13.5 0.2 1.5 1 0 0 1 1 1 0 Flagellar assembly protein T, N-terminal domain HSP70 PF00012.20 CBZ28656.1 - 1.8e-192 640.8 4.0 2.1e-192 640.5 4.0 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 CBZ28656.1 - 6.9e-17 61.3 4.7 1.8e-14 53.3 0.2 2.7 3 0 0 3 3 3 2 MreB/Mbl protein FtsA PF14450.6 CBZ28656.1 - 0.00016 22.0 1.5 0.31 11.5 0.0 3.6 3 1 0 3 3 3 2 Cell division protein FtsA BcrAD_BadFG PF01869.20 CBZ28656.1 - 0.0016 18.0 0.7 0.031 13.8 0.1 2.8 2 1 0 2 2 2 1 BadF/BadG/BcrA/BcrD ATPase family Phage_TAC_11 PF11836.8 CBZ28656.1 - 0.0027 17.8 0.1 0.012 15.7 0.0 2.1 2 0 0 2 2 2 1 Phage tail tube protein, GTA-gp10 Raco_middle PF17651.1 CBZ28656.1 - 0.061 13.0 0.2 0.34 10.6 0.0 2.3 2 0 0 2 2 2 0 RACo middle region Hydantoinase_A PF01968.18 CBZ28656.1 - 4.1 6.6 8.3 1.2 8.3 0.1 3.6 5 0 0 5 5 5 0 Hydantoinase/oxoprolinase F-box PF00646.33 CBZ28659.1 - 0.09 12.7 0.0 0.2 11.6 0.0 1.5 1 0 0 1 1 1 0 F-box domain DUF3446 PF11928.8 CBZ28659.1 - 9.6 6.6 8.8 12 6.3 0.0 3.1 3 0 0 3 3 3 0 Early growth response N-terminal domain Ldh_1_N PF00056.23 CBZ28660.1 - 6.8e-33 113.7 0.0 1.1e-32 113.0 0.0 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.18 CBZ28660.1 - 5.4e-29 101.3 0.0 7.9e-29 100.7 0.0 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain AAA_6 PF12774.7 CBZ28662.1 - 4.1e-150 499.3 0.0 1e-149 498.0 0.0 1.7 1 0 0 1 1 1 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 CBZ28662.1 - 8.9e-104 347.7 2.5 8.9e-104 347.7 2.5 3.5 4 0 0 4 4 3 1 Dynein heavy chain, N-terminal region 2 AAA_8 PF12780.7 CBZ28662.1 - 1.6e-100 335.7 0.0 5.5e-100 334.0 0.0 2.0 2 0 0 2 2 2 1 P-loop containing dynein motor region D4 Dynein_C PF18199.1 CBZ28662.1 - 9.5e-82 274.6 0.4 7.7e-80 268.4 0.0 4.1 4 0 0 4 4 4 1 Dynein heavy chain C-terminal domain AAA_9 PF12781.7 CBZ28662.1 - 7.5e-79 263.9 0.0 8.1e-77 257.3 0.1 2.9 2 0 0 2 2 2 1 ATP-binding dynein motor region AAA_7 PF12775.7 CBZ28662.1 - 3.4e-71 238.5 0.3 4.4e-65 218.6 0.0 4.1 4 0 0 4 4 4 3 P-loop containing dynein motor region AAA_lid_11 PF18198.1 CBZ28662.1 - 8.3e-53 178.6 0.0 2.1e-52 177.2 0.0 1.8 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain Dynein_heavy PF03028.15 CBZ28662.1 - 4.4e-43 146.2 0.1 2e-41 140.8 0.0 3.7 3 0 0 3 3 3 1 Dynein heavy chain region D6 P-loop domain MT PF12777.7 CBZ28662.1 - 4e-41 141.2 10.7 8e-41 140.2 10.7 1.5 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor Dynein_AAA_lid PF17852.1 CBZ28662.1 - 4.9e-25 88.1 0.0 2.1e-24 86.0 0.0 2.3 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain AAA_5 PF07728.14 CBZ28662.1 - 2.3e-24 86.0 0.0 7.3e-07 29.3 0.0 6.0 6 1 0 6 6 6 4 AAA domain (dynein-related subfamily) AAA_lid_1 PF17857.1 CBZ28662.1 - 6e-12 45.7 0.2 2e-11 43.9 0.0 2.1 2 0 0 2 2 1 1 AAA+ lid domain AAA PF00004.29 CBZ28662.1 - 7.6e-09 36.1 0.5 0.056 13.9 0.0 4.9 4 0 0 4 4 4 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 CBZ28662.1 - 5e-08 33.5 8.9 4.1 7.8 0.1 7.7 6 1 1 7 7 7 3 AAA ATPase domain AAA_18 PF13238.6 CBZ28662.1 - 1e-05 26.1 0.0 0.087 13.4 0.0 4.6 4 0 0 4 4 4 1 AAA domain AAA_22 PF13401.6 CBZ28662.1 - 0.00058 20.2 10.3 3 8.1 0.0 5.9 6 0 0 6 6 5 1 AAA domain Sigma54_activat PF00158.26 CBZ28662.1 - 0.00099 18.8 0.3 0.42 10.3 0.0 3.8 4 0 0 4 4 4 1 Sigma-54 interaction domain AAA_14 PF13173.6 CBZ28662.1 - 0.0011 19.0 0.0 0.63 10.1 0.0 3.1 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 CBZ28662.1 - 0.002 18.5 0.0 0.38 11.2 0.0 3.9 3 0 0 3 3 3 1 RNA helicase ResIII PF04851.15 CBZ28662.1 - 0.0084 16.1 1.0 0.31 11.0 0.1 3.4 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit AAA_33 PF13671.6 CBZ28662.1 - 0.063 13.4 0.8 61 3.8 0.0 4.3 4 0 0 4 4 4 0 AAA domain AAA_lid_7 PF17867.1 CBZ28662.1 - 0.087 13.0 0.1 0.46 10.7 0.1 2.3 1 0 0 1 1 1 0 Midasin AAA lid domain NACHT PF05729.12 CBZ28662.1 - 0.44 10.4 7.8 2.3 8.1 0.0 4.6 6 0 0 6 6 4 0 NACHT domain SRP54 PF00448.22 CBZ28662.1 - 0.74 9.4 4.5 20 4.7 0.1 4.2 4 0 0 4 4 4 0 SRP54-type protein, GTPase domain AAA_19 PF13245.6 CBZ28662.1 - 0.87 9.9 4.7 59 4.0 0.0 4.5 4 0 0 4 4 4 0 AAA domain DUF853 PF05872.12 CBZ28662.1 - 5.2 5.5 13.5 0.03 12.9 0.1 2.7 3 0 0 3 3 2 0 Bacterial protein of unknown function (DUF853) Dor1 PF04124.12 CBZ28664.1 - 2.7e-23 82.2 6.4 3.5e-23 81.8 6.4 1.1 1 0 0 1 1 1 1 Dor1-like family Exo84_C PF16528.5 CBZ28664.1 - 3.4e-06 27.0 0.7 6.5e-06 26.1 0.7 1.5 1 0 0 1 1 1 1 Exocyst component 84 C-terminal TPR_16 PF13432.6 CBZ28664.1 - 1.5 9.5 4.4 0.42 11.3 0.7 2.0 2 0 0 2 2 2 0 Tetratricopeptide repeat ELFV_dehydrog PF00208.21 CBZ28665.1 - 2.8e-86 289.2 4.0 3.8e-86 288.8 4.0 1.1 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ELFV_dehydrog_N PF02812.18 CBZ28665.1 - 1.1e-49 167.6 0.0 2.9e-49 166.3 0.0 1.8 1 0 0 1 1 1 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain NAD_binding_7 PF13241.6 CBZ28665.1 - 0.001 19.5 0.2 0.0019 18.6 0.2 1.4 1 0 0 1 1 1 1 Putative NAD(P)-binding LdpA_C PF12617.8 CBZ28665.1 - 0.012 15.3 0.0 0.022 14.4 0.0 1.5 1 0 0 1 1 1 0 Iron-Sulfur binding protein C terminal 2-Hacid_dh_C PF02826.19 CBZ28665.1 - 0.052 12.9 0.1 0.094 12.1 0.1 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Na_sulph_symp PF00939.19 CBZ28667.1 - 9e-22 77.7 44.9 7.8e-21 74.7 44.9 2.8 1 1 0 1 1 1 1 Sodium:sulfate symporter transmembrane region CitMHS PF03600.16 CBZ28667.1 - 3.9e-19 69.0 70.1 5.9e-17 61.8 45.1 1.8 1 1 1 2 2 2 2 Citrate transporter SPX PF03105.19 CBZ28667.1 - 1e-06 28.9 7.8 3.1e-06 27.4 0.5 2.4 1 1 1 2 2 2 2 SPX domain zf-CCCH_4 PF18044.1 CBZ28669.1 - 0.015 15.1 0.6 0.015 15.1 0.6 2.3 2 1 0 2 2 2 0 CCCH-type zinc finger zf-CCCH PF00642.24 CBZ28669.1 - 0.072 13.0 5.7 3.7 7.6 0.3 2.5 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 CBZ28669.1 - 2.5 8.3 9.0 0.19 11.9 2.3 2.3 2 0 0 2 2 2 0 Zinc finger domain WD40 PF00400.32 CBZ28670.1 - 0.036 14.9 10.8 2.1 9.4 0.6 4.9 4 0 0 4 4 4 0 WD domain, G-beta repeat DUF2828 PF11443.8 CBZ28670.1 - 0.061 11.4 0.0 0.15 10.1 0.0 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF2828) PQQ_3 PF13570.6 CBZ28670.1 - 7.5 7.2 14.3 17 6.0 0.6 5.7 5 1 1 6 6 6 0 PQQ-like domain DUF1192 PF06698.11 CBZ28674.1 - 0.00095 19.2 0.6 0.0035 17.4 0.1 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF1192) Pkinase PF00069.25 CBZ28675.1 - 2.5e-47 161.5 0.0 2.9e-47 161.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ28675.1 - 4.1e-27 95.1 0.0 5e-27 94.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CBZ28675.1 - 3.9e-05 23.1 0.0 5.7e-05 22.6 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 CBZ28675.1 - 0.013 14.3 0.0 0.018 13.8 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase Acetyltransf_1 PF00583.25 CBZ28676.1 - 6.9e-14 52.1 0.0 8e-14 51.9 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 CBZ28676.1 - 3.3e-10 40.0 0.0 4.2e-10 39.6 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 CBZ28676.1 - 2.7e-08 34.1 0.0 3.8e-08 33.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 CBZ28676.1 - 4.7e-05 23.5 0.0 6.3e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 CBZ28676.1 - 0.00062 19.8 0.1 0.00095 19.3 0.1 1.3 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_3 PF13302.7 CBZ28676.1 - 0.01 16.5 0.0 0.012 16.3 0.0 1.1 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain FR47 PF08445.10 CBZ28676.1 - 0.044 13.7 0.0 0.079 12.9 0.0 1.5 1 0 0 1 1 1 0 FR47-like protein HscB_4_cys PF18256.1 CBZ28678.1 - 0.069 13.0 15.7 33 4.4 0.1 5.8 5 0 0 5 5 5 0 Co-chaperone HscB tetracysteine metal binding motif DUF3035 PF11233.8 CBZ28678.1 - 0.1 12.9 20.4 3.6 7.8 2.2 3.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3035) zf-MIZ PF02891.20 CBZ28678.1 - 0.21 11.4 16.7 22 4.9 0.1 5.6 5 0 0 5 5 5 0 MIZ/SP-RING zinc finger FMN_bind PF04205.14 CBZ28678.1 - 0.22 12.1 8.7 32 5.2 0.2 3.6 3 0 0 3 3 3 0 FMN-binding domain Hydrolase_4 PF12146.8 CBZ28679.1 - 1.5e-07 30.9 0.0 5.4e-05 22.6 0.0 2.1 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 CBZ28679.1 - 3.9e-07 30.9 1.9 3.9e-07 30.9 1.9 1.9 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 CBZ28679.1 - 1.3e-06 28.3 0.3 0.0047 16.6 0.2 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Nrap_D4 PF17405.2 CBZ28679.1 - 0.054 12.8 0.0 2.5 7.4 0.0 2.1 2 0 0 2 2 2 0 Nrap protein nucleotidyltransferase domain 4 Pro_isomerase PF00160.21 CBZ28680.1 - 2.4e-18 66.9 0.0 3.1e-17 63.3 0.0 2.0 1 1 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD UPF0220 PF05255.11 CBZ28682.1 - 8.6e-16 57.9 0.2 1.1e-15 57.6 0.2 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0220) DUF3267 PF11667.8 CBZ28682.1 - 0.0014 18.9 0.2 0.0043 17.3 0.1 1.8 1 1 1 2 2 2 1 Putative zincin peptidase BacA PF02673.18 CBZ28682.1 - 0.026 14.2 0.1 0.036 13.8 0.1 1.3 1 1 0 1 1 1 0 Bacitracin resistance protein BacA MATH PF00917.26 CBZ28683.1 - 3.1e-06 27.3 0.3 3.1e-06 27.3 0.3 2.3 2 0 0 2 2 2 1 MATH domain YL1 PF05764.13 CBZ28683.1 - 0.0068 16.6 8.5 0.0068 16.6 8.5 2.5 2 0 0 2 2 2 1 YL1 nuclear protein CorA PF01544.18 CBZ28683.1 - 0.95 8.7 15.6 0.79 9.0 13.9 1.7 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein REF PF05755.12 CBZ28683.1 - 4.5 7.0 11.3 56 3.4 11.3 2.3 1 1 0 1 1 1 0 Rubber elongation factor protein (REF) Cyclin_N PF00134.23 CBZ28686.1 - 1.5e-23 82.9 0.4 4.3e-23 81.4 0.1 1.9 2 0 0 2 2 2 1 Cyclin, N-terminal domain TERF2_RBM PF16772.5 CBZ28686.1 - 0.15 11.5 0.0 0.44 10.0 0.0 1.8 1 0 0 1 1 1 0 Telomeric repeat-binding factor 2 Rap1-binding motif PQQ_2 PF13360.6 CBZ28688.1 - 0.0028 17.3 0.6 0.28 10.8 0.2 3.0 3 0 0 3 3 3 2 PQQ-like domain AAA_25 PF13481.6 CBZ28688.1 - 0.019 14.6 0.0 0.081 12.5 0.0 2.0 2 0 0 2 2 2 0 AAA domain LRR_4 PF12799.7 CBZ28689.1 - 1e-09 38.5 7.6 0.00012 22.3 0.3 4.5 5 0 0 5 5 5 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CBZ28689.1 - 2e-05 24.2 10.2 0.021 14.6 0.9 4.5 4 1 1 5 5 5 3 Leucine rich repeat LRR_6 PF13516.6 CBZ28689.1 - 0.31 11.2 8.8 39 4.7 0.2 5.5 6 0 0 6 6 6 0 Leucine Rich repeat LRR_1 PF00560.33 CBZ28689.1 - 0.92 10.3 5.3 94 4.2 0.0 5.0 6 0 0 6 6 6 0 Leucine Rich Repeat FAD-oxidase_C PF02913.19 CBZ28690.1 - 2.6e-47 161.5 0.0 3.8e-47 161.0 0.0 1.2 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 CBZ28690.1 - 6.1e-39 132.9 0.0 1e-38 132.2 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 CBZ28690.1 - 0.0026 17.8 0.0 0.017 15.2 0.0 2.3 2 0 0 2 2 2 1 Berberine and berberine like tRNA-synt_2 PF00152.20 CBZ28691.1 - 2.8e-78 263.2 0.0 3.5e-78 262.9 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA-synt_2d PF01409.20 CBZ28691.1 - 1.9e-09 37.4 0.1 0.00032 20.2 0.0 2.4 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) tRNA_anti-codon PF01336.25 CBZ28691.1 - 4.1e-07 29.9 0.0 7.4e-07 29.1 0.0 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain FCD PF07729.12 CBZ28691.1 - 0.14 12.6 1.4 0.43 11.0 0.1 2.5 3 0 0 3 3 3 0 FCD domain Yip1 PF04893.17 CBZ28692.1 - 1.3e-09 38.0 17.8 2.9e-09 36.9 17.6 1.5 1 1 0 1 1 1 1 Yip1 domain LRR_6 PF13516.6 CBZ28693.1 - 5e-31 104.1 4.7 1e-06 28.3 0.1 5.2 5 0 0 5 5 5 5 Leucine Rich repeat LRR_4 PF12799.7 CBZ28693.1 - 1.6e-08 34.7 0.7 0.00042 20.7 0.1 3.1 2 1 2 4 4 4 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 CBZ28693.1 - 4.2e-05 23.5 0.0 0.61 10.9 0.0 4.4 4 0 0 4 4 4 1 Leucine Rich Repeat LRR_8 PF13855.6 CBZ28693.1 - 5e-05 23.0 0.9 0.023 14.5 1.4 3.7 1 1 2 3 3 3 2 Leucine rich repeat Pou PF00157.17 CBZ28693.1 - 0.17 11.9 0.0 0.63 10.0 0.0 2.0 1 1 1 2 2 2 0 Pou domain - N-terminal to homeobox domain Rubis-subs-bind PF09273.11 CBZ28694.1 - 4.3e-11 43.6 0.0 1.9e-10 41.6 0.0 2.0 2 0 0 2 2 2 1 Rubisco LSMT substrate-binding SET PF00856.28 CBZ28694.1 - 0.01 16.2 0.0 0.019 15.4 0.0 1.5 1 1 0 1 1 1 0 SET domain NAD_binding_2 PF03446.15 CBZ28695.1 - 2.4e-50 170.8 0.8 4.4e-50 169.9 0.8 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 CBZ28695.1 - 1.3e-36 125.5 0.5 2.3e-36 124.7 0.5 1.4 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 2-Hacid_dh_C PF02826.19 CBZ28695.1 - 2e-05 24.0 0.4 0.00016 21.1 0.0 2.3 3 0 0 3 3 3 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain F420_oxidored PF03807.17 CBZ28695.1 - 8.4e-05 23.1 0.2 0.00053 20.5 0.0 2.4 3 1 0 3 3 3 1 NADP oxidoreductase coenzyme F420-dependent Shikimate_DH PF01488.20 CBZ28695.1 - 0.00056 20.0 0.0 0.0012 18.9 0.0 1.6 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase 3HCDH_N PF02737.18 CBZ28695.1 - 0.0022 17.9 0.0 0.0049 16.8 0.0 1.7 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain IlvN PF07991.12 CBZ28695.1 - 0.011 15.4 0.1 0.026 14.1 0.0 1.7 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain UDPG_MGDP_dh_N PF03721.14 CBZ28695.1 - 0.018 14.6 0.1 7.6 6.1 0.0 2.3 1 1 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain ApbA PF02558.16 CBZ28695.1 - 0.039 13.6 0.0 0.069 12.8 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Sacchrp_dh_NADP PF03435.18 CBZ28695.1 - 0.044 14.1 0.1 0.19 12.0 0.0 2.2 2 1 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain PDH PF02153.17 CBZ28695.1 - 0.074 12.0 0.0 0.11 11.5 0.0 1.3 1 0 0 1 1 1 0 Prephenate dehydrogenase MGAT2 PF05060.14 CBZ28695.1 - 0.085 11.9 0.0 0.12 11.4 0.0 1.1 1 0 0 1 1 1 0 N-acetylglucosaminyltransferase II (MGAT2) Gly-zipper_Omp PF13488.6 CBZ28698.1 - 0.15 12.1 7.1 0.23 11.5 7.1 1.3 1 0 0 1 1 1 0 Glycine zipper RrnaAD PF00398.20 CBZ28699.1 - 5e-61 206.1 0.0 7.1e-61 205.6 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_25 PF13649.6 CBZ28699.1 - 2e-07 31.6 0.0 3.6e-07 30.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CBZ28699.1 - 5.3e-05 23.8 0.0 0.0001 22.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CBZ28699.1 - 0.0012 19.5 0.0 0.0024 18.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 CBZ28699.1 - 0.0055 16.6 0.0 0.0088 15.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 CBZ28699.1 - 0.019 14.7 0.0 0.029 14.1 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_28 PF02636.17 CBZ28699.1 - 0.038 13.6 0.0 0.057 13.0 0.0 1.2 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase DREV PF05219.12 CBZ28699.1 - 0.06 12.4 0.0 0.1 11.7 0.0 1.3 1 0 0 1 1 1 0 DREV methyltransferase Ubie_methyltran PF01209.18 CBZ28699.1 - 0.08 12.3 0.0 0.15 11.4 0.0 1.4 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_18 PF12847.7 CBZ28699.1 - 0.12 12.3 0.0 0.19 11.6 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain zf-RanBP PF00641.18 CBZ28700.1 - 0.00039 19.7 2.3 0.00039 19.7 2.3 1.7 2 0 0 2 2 2 1 Zn-finger in Ran binding protein and others VHS PF00790.19 CBZ28700.1 - 0.1 12.4 0.0 0.15 12.0 0.0 1.2 1 0 0 1 1 1 0 VHS domain Mito_carr PF00153.27 CBZ28701.1 - 5.7e-11 42.2 0.1 2.2e-06 27.5 0.0 2.5 2 0 0 2 2 2 2 Mitochondrial carrier protein RNase_T PF00929.24 CBZ28703.1 - 1.4e-16 61.4 0.0 3.3e-16 60.3 0.0 1.7 1 0 0 1 1 1 1 Exonuclease UCH_1 PF13423.6 CBZ28703.1 - 1.6e-12 47.7 0.0 1.1e-09 38.4 0.0 2.3 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase UCH PF00443.29 CBZ28703.1 - 0.00012 21.6 0.0 0.0003 20.4 0.0 1.7 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase PCuAC PF04314.13 CBZ28703.1 - 0.097 12.5 0.0 0.29 11.0 0.0 1.8 1 1 0 1 1 1 0 Copper chaperone PCu(A)C zf-C2H2_4 PF13894.6 CBZ28704.1 - 1.6e-16 59.6 48.2 0.005 17.6 0.5 8.5 8 0 0 8 8 8 5 C2H2-type zinc finger zf-C2H2 PF00096.26 CBZ28704.1 - 2.1e-11 43.6 43.5 0.041 14.4 0.7 8.4 8 0 0 8 8 8 6 Zinc finger, C2H2 type zf-Di19 PF05605.12 CBZ28704.1 - 1.2e-10 41.5 31.2 0.0025 18.0 3.5 7.3 7 1 0 7 7 7 4 Drought induced 19 protein (Di19), zinc-binding zf-met PF12874.7 CBZ28704.1 - 5.4e-10 39.3 7.0 0.0033 17.8 0.7 5.3 4 0 0 4 4 4 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 CBZ28704.1 - 9.1e-08 32.2 12.4 0.016 15.5 0.1 5.4 6 0 0 6 6 6 2 Zinc-finger double-stranded RNA-binding Actin_micro PF17003.5 CBZ28704.1 - 4.3e-06 26.2 3.2 1.9 7.6 0.0 5.0 5 0 0 5 5 5 2 Putative actin-like family zf-H2C2_2 PF13465.6 CBZ28704.1 - 2.6e-05 24.4 26.6 0.16 12.4 0.3 8.3 8 2 0 8 8 7 2 Zinc-finger double domain TRAF6_Z2 PF18048.1 CBZ28704.1 - 0.0051 16.9 2.8 7.3 6.8 0.0 4.2 4 0 0 4 4 4 0 TNF receptor-associated factor 6 zinc finger 2 zf-met2 PF12907.7 CBZ28704.1 - 0.011 15.9 8.5 1.3 9.2 0.2 4.4 5 0 0 5 5 5 0 Zinc-binding DUF4729 PF15866.5 CBZ28704.1 - 0.014 14.7 8.2 0.77 9.0 0.2 4.2 5 0 0 5 5 5 0 Domain of unknown function (DUF4729) DUF629 PF04780.12 CBZ28704.1 - 0.071 11.6 15.4 1.6 7.2 0.1 5.6 4 1 2 6 6 6 0 Protein of unknown function (DUF629) zf-C2H2_3rep PF18868.1 CBZ28704.1 - 0.14 12.8 18.0 0.19 12.4 0.7 5.4 4 2 3 7 7 7 0 Zinc finger C2H2-type, 3 repeats zf-H2C2_5 PF13909.6 CBZ28704.1 - 0.23 11.2 0.1 0.23 11.2 0.1 4.0 4 0 0 4 4 3 0 C2H2-type zinc-finger domain CxC7 PF18866.1 CBZ28704.1 - 0.32 11.2 2.2 9.4 6.5 0.1 3.6 3 0 0 3 3 3 0 CxC7 like cysteine cluster associated with KDZ transposases zf-C2H2_9 PF16293.5 CBZ28704.1 - 0.34 10.8 15.9 4.3 7.3 0.2 5.2 6 0 0 6 6 6 0 C2H2 type zinc-finger (1 copy) gag_pre-integrs PF13976.6 CBZ28704.1 - 1.3 8.9 4.4 0.99 9.3 0.1 3.0 3 0 0 3 3 2 0 GAG-pre-integrase domain zf-C2H2_2 PF12756.7 CBZ28704.1 - 1.4 9.3 21.8 3.7 7.9 0.2 6.3 5 1 0 5 5 5 0 C2H2 type zinc-finger (2 copies) Anti-TRAP PF15777.5 CBZ28704.1 - 2 8.5 5.3 15 5.6 0.0 4.0 4 0 0 4 4 4 0 Tryptophan RNA-binding attenuator protein inhibitory protein Evr1_Alr PF04777.13 CBZ28704.1 - 2.2 8.8 9.7 11 6.5 0.1 4.9 3 1 2 5 5 5 0 Erv1 / Alr family zf-C2HC_2 PF13913.6 CBZ28704.1 - 2.4 8.2 20.2 0.046 13.6 1.1 4.4 5 0 0 5 5 5 0 zinc-finger of a C2HC-type FOXP-CC PF16159.5 CBZ28704.1 - 2.7 8.7 23.7 1.1e+02 3.5 0.0 7.5 6 2 2 8 8 8 0 FOXP coiled-coil domain zf-TFIIB PF13453.6 CBZ28704.1 - 4.2 6.8 12.8 0.43 10.0 1.1 3.5 4 0 0 4 4 4 0 Transcription factor zinc-finger zf-C2H2_11 PF16622.5 CBZ28704.1 - 4.9 7.0 9.9 2.7 7.8 0.1 4.2 4 0 0 4 4 4 0 zinc-finger C2H2-type IBR PF01485.21 CBZ28704.1 - 5.9 7.2 8.6 39 4.6 0.1 3.9 4 0 0 4 4 3 0 IBR domain, a half RING-finger domain DUF3795 PF12675.7 CBZ28704.1 - 6.4 7.3 7.3 8.4 6.9 1.7 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3795) Peptidase_C54 PF03416.19 CBZ28705.1 - 3.7e-45 154.5 0.0 7.5e-45 153.5 0.0 1.4 1 1 0 1 1 1 1 Peptidase family C54 COP23 PF14218.6 CBZ28705.1 - 0.02 14.7 0.1 0.04 13.7 0.1 1.5 1 0 0 1 1 1 0 Circadian oscillating protein COP23 Peptidase_C78 PF07910.13 CBZ28705.1 - 0.037 13.5 0.0 0.081 12.4 0.0 1.5 1 0 0 1 1 1 0 Peptidase family C78 LIM PF00412.22 CBZ28706.1 - 3.7e-05 23.9 12.0 9.1e-05 22.6 9.3 2.4 2 1 0 2 2 2 1 LIM domain NCD3G PF07562.14 CBZ28706.1 - 0.078 13.0 4.9 4.3 7.4 1.3 2.4 2 0 0 2 2 2 0 Nine Cysteines Domain of family 3 GPCR CSN5_C PF18323.1 CBZ28709.1 - 3 8.8 10.0 12 6.9 0.8 4.2 3 0 0 3 3 3 0 Cop9 signalosome subunit 5 C-terminal domain Sad1_UNC PF07738.13 CBZ28710.1 - 8.4e-18 64.7 0.0 1.3e-17 64.1 0.0 1.2 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal RabGAP-TBC PF00566.18 CBZ28711.1 - 1.3e-06 28.2 0.4 2.1e-06 27.5 0.4 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Rhodanese PF00581.20 CBZ28711.1 - 0.01 16.4 0.0 0.027 15.0 0.0 1.7 1 0 0 1 1 1 0 Rhodanese-like domain Ku PF02735.16 CBZ28712.1 - 1.1e-29 103.7 0.0 2.4e-29 102.5 0.0 1.5 1 0 0 1 1 1 1 Ku70/Ku80 beta-barrel domain Ku_PK_bind PF08785.11 CBZ28712.1 - 1e-21 77.3 0.0 2.6e-21 76.0 0.0 1.7 2 0 0 2 2 2 1 Ku C terminal domain like Ku_N PF03731.15 CBZ28712.1 - 6e-09 36.0 0.0 1.7e-08 34.5 0.0 1.7 1 1 0 1 1 1 1 Ku70/Ku80 N-terminal alpha/beta domain VWA PF00092.28 CBZ28712.1 - 0.00024 21.4 0.0 0.0011 19.2 0.0 2.1 3 0 0 3 3 3 1 von Willebrand factor type A domain VWA_2 PF13519.6 CBZ28712.1 - 0.013 16.1 0.0 0.18 12.4 0.0 2.7 2 0 0 2 2 2 0 von Willebrand factor type A domain Ku_C PF03730.14 CBZ28712.1 - 0.13 13.0 0.0 0.35 11.6 0.0 1.7 1 0 0 1 1 1 0 Ku70/Ku80 C-terminal arm Kinesin PF00225.23 CBZ28713.1 - 1.9e-90 303.2 0.1 2.9e-90 302.6 0.1 1.3 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 CBZ28713.1 - 7.7e-26 90.8 0.0 3.7e-25 88.6 0.0 2.2 1 0 0 1 1 1 1 Microtubule binding AAA_16 PF13191.6 CBZ28713.1 - 0.0091 16.4 1.1 0.045 14.1 0.0 2.6 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 CBZ28713.1 - 0.012 15.8 0.1 0.24 11.7 0.0 2.9 2 1 1 3 3 3 0 AAA domain DivIC PF04977.15 CBZ28713.1 - 0.017 14.9 9.4 0.21 11.4 0.4 3.4 3 0 0 3 3 3 0 Septum formation initiator Pou PF00157.17 CBZ28713.1 - 0.061 13.3 3.0 0.2 11.7 0.3 2.8 3 0 0 3 3 3 0 Pou domain - N-terminal to homeobox domain NRBF2 PF08961.10 CBZ28713.1 - 0.14 11.7 3.0 0.33 10.5 3.0 1.5 1 0 0 1 1 1 0 Nuclear receptor-binding factor 2, autophagy regulator RNase_PH_C PF03725.15 CBZ28713.1 - 0.19 11.8 0.4 1.7 8.8 0.1 2.7 3 0 0 3 3 2 0 3' exoribonuclease family, domain 2 TSC22 PF01166.18 CBZ28713.1 - 0.22 11.8 4.0 0.16 12.3 1.1 2.4 2 0 0 2 2 2 0 TSC-22/dip/bun family PIF1 PF05970.14 CBZ28713.1 - 0.47 9.6 4.6 0.09 11.9 0.3 1.8 2 0 0 2 2 2 0 PIF1-like helicase FtsK_SpoIIIE PF01580.18 CBZ28713.1 - 0.61 9.4 3.1 6 6.1 0.0 3.5 4 0 0 4 4 4 0 FtsK/SpoIIIE family DUF4407 PF14362.6 CBZ28713.1 - 0.65 9.3 7.8 2.2 7.6 7.8 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) YabA PF06156.13 CBZ28713.1 - 1.8 9.3 11.6 0.49 11.1 5.8 2.7 1 1 1 2 2 2 0 Initiation control protein YabA ZapB PF06005.12 CBZ28713.1 - 2.5 8.6 15.5 2.5e+02 2.2 2.8 3.1 1 1 1 2 2 2 0 Cell division protein ZapB USP8_interact PF08941.10 CBZ28713.1 - 5.1 6.9 8.4 9.1 6.1 2.6 2.4 2 0 0 2 2 2 0 USP8 interacting EMP70 PF02990.16 CBZ28714.1 - 5.5e-147 490.6 9.6 8.3e-147 490.0 9.6 1.2 1 0 0 1 1 1 1 Endomembrane protein 70 Pkinase PF00069.25 CBZ28715.1 - 2.1e-60 204.4 0.0 1.1e-59 201.9 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ28715.1 - 1.3e-26 93.5 0.0 1.8e-26 93.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CBZ28715.1 - 7.8e-05 22.1 0.0 0.00021 20.7 0.0 1.6 2 0 0 2 2 2 1 Kinase-like DUF3455 PF11937.8 CBZ28715.1 - 0.16 12.4 0.0 0.27 11.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3455) Seadorna_VP7 PF07387.11 CBZ28715.1 - 0.2 10.7 0.0 0.34 9.9 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 PP2C PF00481.21 CBZ28716.1 - 7.1e-49 166.8 0.1 9.5e-49 166.3 0.1 1.1 1 0 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.12 CBZ28716.1 - 0.00094 19.1 0.0 0.0034 17.3 0.0 1.9 1 1 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) Hydrolase_4 PF12146.8 CBZ28718.1 - 2.4e-12 46.6 0.0 1.2e-09 37.8 0.0 2.2 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 CBZ28718.1 - 7.2e-09 35.7 0.1 9.3e-06 25.5 0.1 2.4 1 1 0 2 2 2 2 alpha/beta hydrolase fold Peptidase_S15 PF02129.18 CBZ28718.1 - 2.1e-08 34.1 0.0 1.3e-07 31.5 0.0 2.0 2 0 0 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_6 PF12697.7 CBZ28718.1 - 0.00021 22.0 0.2 0.00045 20.9 0.1 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 CBZ28718.1 - 0.00081 18.9 0.0 0.012 15.1 0.0 2.1 1 1 0 1 1 1 1 Prolyl oligopeptidase family Esterase PF00756.20 CBZ28718.1 - 0.015 14.9 0.0 0.023 14.4 0.0 1.2 1 0 0 1 1 1 0 Putative esterase AXE1 PF05448.12 CBZ28718.1 - 0.026 13.2 0.0 1.5 7.4 0.0 2.3 1 1 0 1 1 1 0 Acetyl xylan esterase (AXE1) BAAT_C PF08840.11 CBZ28718.1 - 0.21 11.5 0.0 0.4 10.6 0.0 1.5 1 1 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal PAP2 PF01569.21 CBZ28719.1 - 7.9e-24 84.0 4.5 1.4e-23 83.2 4.5 1.3 1 0 0 1 1 1 1 PAP2 superfamily Glucos_trans_II PF14264.6 CBZ28719.1 - 0.066 12.6 1.7 0.47 9.8 0.4 2.1 2 0 0 2 2 2 0 Glucosyl transferase GtrII WD40 PF00400.32 CBZ28720.1 - 6.4e-30 102.8 14.4 5e-09 36.7 0.5 7.4 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBZ28720.1 - 3.5e-16 59.3 0.2 5.7e-05 23.3 0.0 5.4 2 1 3 5 5 5 5 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 CBZ28720.1 - 0.00045 19.3 0.0 0.03 13.3 0.0 2.6 1 1 2 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein DAGK_cat PF00781.24 CBZ28721.1 - 3.2e-14 52.6 0.1 5.1e-14 52.0 0.1 1.3 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain Evr1_Alr PF04777.13 CBZ28722.1 - 6.6e-13 49.0 0.0 2.8e-12 47.0 0.0 2.2 1 0 0 1 1 1 1 Erv1 / Alr family Thioredoxin PF00085.20 CBZ28722.1 - 6.2e-07 29.4 0.0 1.5e-06 28.1 0.0 1.6 1 1 0 1 1 1 1 Thioredoxin BIV_Env PF05858.12 CBZ28722.1 - 0.16 10.1 0.0 0.24 9.5 0.0 1.2 1 0 0 1 1 1 0 Bovine immunodeficiency virus surface protein (SU) DUF4330 PF14221.6 CBZ28722.1 - 0.65 10.2 2.0 4.8 7.4 0.5 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4330) DUF4051 PF13260.6 CBZ28722.1 - 0.85 9.4 2.6 2.5 7.9 2.6 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF4051) RRF PF01765.19 CBZ28723.1 - 1.6e-15 57.5 0.9 1.6e-15 57.5 0.9 1.8 1 1 1 2 2 2 1 Ribosome recycling factor IF4E PF01652.18 CBZ28724.1 - 1.8e-27 96.1 0.0 2.4e-27 95.7 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E tRNA-synt_2 PF00152.20 CBZ28725.1 - 2e-74 250.5 0.0 2.9e-74 250.0 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 CBZ28725.1 - 2.2e-09 37.2 0.1 4e-09 36.3 0.1 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 CBZ28725.1 - 0.00031 20.3 0.2 0.25 10.8 0.0 2.5 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) Bystin PF05291.11 CBZ28727.1 - 9.7e-110 366.4 0.1 1.3e-109 366.0 0.1 1.1 1 0 0 1 1 1 1 Bystin DUF3299 PF11736.8 CBZ28727.1 - 0.011 15.7 0.1 0.072 13.1 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3299) Med9 PF07544.13 CBZ28728.1 - 6.7 6.9 23.2 0.57 10.3 4.9 3.9 4 0 0 4 4 4 0 RNA polymerase II transcription mediator complex subunit 9 XAP5 PF04921.14 CBZ28730.1 - 0.15 11.8 1.3 0.37 10.6 1.3 1.6 1 0 0 1 1 1 0 XAP5, circadian clock regulator YL1 PF05764.13 CBZ28730.1 - 0.23 11.6 18.4 0.061 13.4 8.0 2.2 2 0 0 2 2 2 0 YL1 nuclear protein C_Hendra PF16821.5 CBZ28730.1 - 2.1 8.2 6.7 0.12 12.3 0.5 2.0 2 0 0 2 2 2 0 C protein from hendra and measles viruses LRR_4 PF12799.7 CBZ28731.1 - 6.2e-07 29.6 0.3 0.0098 16.3 0.0 3.1 3 0 0 3 3 3 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CBZ28731.1 - 0.0044 16.8 0.1 0.025 14.3 0.1 2.0 1 1 0 1 1 1 1 Leucine rich repeat LRR_9 PF14580.6 CBZ28731.1 - 0.1 12.1 0.0 0.19 11.3 0.0 1.3 1 0 0 1 1 1 0 Leucine-rich repeat NatB_MDM20 PF09797.9 CBZ28732.1 - 5.2e-28 98.1 0.0 3.4e-27 95.4 0.0 2.1 2 0 0 2 2 2 1 N-acetyltransferase B complex (NatB) non catalytic subunit TPR_16 PF13432.6 CBZ28732.1 - 0.56 10.9 12.4 0.6 10.8 2.1 4.5 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.6 CBZ28732.1 - 2.4 9.2 19.7 0.26 12.2 1.1 6.0 5 1 1 6 6 6 0 Tetratricopeptide repeat Alg14 PF08660.11 CBZ28733.1 - 5.9e-58 195.7 0.0 8.9e-58 195.1 0.0 1.3 1 0 0 1 1 1 1 Oligosaccharide biosynthesis protein Alg14 like Glyco_tran_28_C PF04101.16 CBZ28733.1 - 7.8e-19 68.3 0.0 2.8e-18 66.4 0.0 1.9 2 1 0 2 2 2 1 Glycosyltransferase family 28 C-terminal domain CLIP_SPH_mas PF18398.1 CBZ28733.1 - 0.71 10.3 2.6 0.47 10.9 0.4 1.9 2 0 0 2 2 2 0 Clip-domain serine protease homolog masquerade RRM_1 PF00076.22 CBZ28734.1 - 4.6e-16 58.4 0.0 7.1e-16 57.8 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) LMBR1 PF04791.16 CBZ28735.1 - 4e-54 184.4 22.0 5.2e-54 184.0 22.0 1.0 1 0 0 1 1 1 1 LMBR1-like membrane protein DUF3037 PF11236.8 CBZ28736.1 - 0.29 11.6 4.7 1.1 9.7 0.1 2.7 1 1 2 3 3 3 0 Protein of unknown function (DUF3037) UPF0565 PF10561.9 CBZ28736.1 - 1.1 8.4 3.4 0.83 8.8 2.3 1.4 1 1 0 1 1 1 0 Uncharacterised protein family UPF0565 Ly49 PF08391.10 CBZ28736.1 - 1.1 9.6 6.3 0.31 11.4 0.5 2.6 3 0 0 3 3 3 0 Ly49-like protein, N-terminal region CTP_transf_like PF01467.26 CBZ28736.1 - 1.5 9.1 3.9 4.2 7.6 3.9 2.0 1 1 0 1 1 1 0 Cytidylyltransferase-like PSP PF04046.16 CBZ28737.1 - 7.1e-19 67.4 1.8 1.9e-18 66.1 1.8 1.8 1 0 0 1 1 1 1 PSP DUF382 PF04037.13 CBZ28737.1 - 9.5e-12 45.2 0.0 1.5e-10 41.3 0.0 2.4 1 1 0 1 1 1 1 Domain of unknown function (DUF382) LUC7 PF03194.15 CBZ28737.1 - 0.43 10.2 10.3 0.61 9.7 10.3 1.2 1 0 0 1 1 1 0 LUC7 N_terminus AMP-binding PF00501.28 CBZ28738.1 - 7.5e-26 90.7 0.0 3.5e-12 45.7 0.0 2.1 2 0 0 2 2 2 2 AMP-binding enzyme BBS2_C PF14782.6 CBZ28739.1 - 1.5e-125 419.4 0.0 2e-125 419.0 0.0 1.1 1 0 0 1 1 1 1 Ciliary BBSome complex subunit 2, C-terminal BBS2_Mid PF14783.6 CBZ28739.1 - 3.4e-23 81.8 0.0 3.9e-22 78.3 0.0 2.8 2 1 0 2 2 2 1 Ciliary BBSome complex subunit 2, middle region FG-GAP PF01839.23 CBZ28739.1 - 0.001 19.1 1.3 0.002 18.2 0.5 1.8 2 0 0 2 2 2 1 FG-GAP repeat VCBS PF13517.6 CBZ28739.1 - 0.0018 18.8 1.9 0.07 13.7 0.4 1.8 1 1 1 2 2 2 2 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FlgN PF05130.12 CBZ28739.1 - 0.017 15.6 1.8 0.017 15.6 1.8 2.4 2 1 1 3 3 3 0 FlgN protein APG6_N PF17675.1 CBZ28739.1 - 3.2 8.3 8.1 0.46 11.0 3.5 1.8 2 0 0 2 2 2 0 Apg6 coiled-coil region HALZ PF02183.18 CBZ28739.1 - 8.5 6.7 8.4 1 9.7 3.5 2.0 2 0 0 2 2 2 0 Homeobox associated leucine zipper Pkinase PF00069.25 CBZ28740.1 - 5e-66 222.8 0.0 6.6e-66 222.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ28740.1 - 2.5e-41 141.7 0.0 3.6e-41 141.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CBZ28740.1 - 0.00027 20.4 0.0 0.00093 18.6 0.0 1.7 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 CBZ28740.1 - 0.0095 14.7 0.0 0.036 12.9 0.0 1.9 1 1 1 2 2 2 1 Fungal protein kinase Cyt-b5 PF00173.28 CBZ28741.1 - 1.5e-24 86.0 0.0 6.8e-16 58.2 0.0 2.5 2 0 0 2 2 2 2 Cytochrome b5-like Heme/Steroid binding domain NAD_binding_1 PF00175.21 CBZ28741.1 - 6.5e-10 39.6 0.0 2.4e-09 37.8 0.0 2.0 1 1 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.12 CBZ28741.1 - 4.8e-06 26.8 0.0 0.00092 19.4 0.0 2.3 2 0 0 2 2 2 2 Ferric reductase NAD binding domain FAD_binding_6 PF00970.24 CBZ28741.1 - 7.3e-06 26.3 0.0 1.9e-05 24.9 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain RRS1 PF04939.12 CBZ28742.1 - 4.4e-41 140.5 5.2 4.4e-41 140.5 5.2 1.6 2 0 0 2 2 2 1 Ribosome biogenesis regulatory protein (RRS1) Ntox33 PF15533.6 CBZ28742.1 - 0.048 14.2 0.1 0.089 13.3 0.1 1.4 1 0 0 1 1 1 0 Bacterial toxin 33 EMC3_TMCO1 PF01956.16 CBZ28742.1 - 2.4 7.8 5.3 6.2 6.5 5.3 1.6 1 1 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like tRNA-synt_His PF13393.6 CBZ28743.1 - 8.9e-35 120.4 0.0 1.3e-34 119.9 0.0 1.2 1 0 0 1 1 1 1 Histidyl-tRNA synthetase HGTP_anticodon PF03129.20 CBZ28743.1 - 4.1e-07 30.1 0.2 1.6e-06 28.2 0.1 2.0 2 0 0 2 2 2 1 Anticodon binding domain tRNA-synt_2b PF00587.25 CBZ28743.1 - 3.8e-05 23.7 0.0 5.2e-05 23.3 0.0 1.4 1 1 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) DUF1965 PF09248.10 CBZ28745.1 - 0.14 11.9 0.1 0.45 10.3 0.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF1965) PDZ_2 PF13180.6 CBZ28746.1 - 1.5e-10 41.2 0.1 4.1e-10 39.9 0.1 1.7 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 CBZ28746.1 - 8.8e-08 31.9 0.0 2.5e-07 30.4 0.0 1.8 1 0 0 1 1 1 1 PDZ domain PI-PLC-X PF00388.19 CBZ28746.1 - 2e-06 27.5 0.0 3.9e-06 26.5 0.0 1.5 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PDZ PF00595.24 CBZ28746.1 - 4.6e-06 26.9 0.0 1.1e-05 25.7 0.0 1.6 1 0 0 1 1 1 1 PDZ domain EF-hand_like PF09279.11 CBZ28746.1 - 0.028 14.9 0.1 0.063 13.8 0.1 1.6 1 0 0 1 1 1 0 Phosphoinositide-specific phospholipase C, efhand-like PI-PLC-Y PF00387.19 CBZ28746.1 - 0.067 13.5 0.0 0.17 12.3 0.0 1.7 1 0 0 1 1 1 0 Phosphatidylinositol-specific phospholipase C, Y domain Ribosomal_S30 PF04758.14 CBZ28747.1 - 4.7e-26 90.7 8.5 5.4e-26 90.6 8.5 1.0 1 0 0 1 1 1 1 Ribosomal protein S30 Ribosomal_S30 PF04758.14 CBZ28748.1 - 4.7e-26 90.7 8.5 5.4e-26 90.6 8.5 1.0 1 0 0 1 1 1 1 Ribosomal protein S30 CS PF04969.16 CBZ28749.1 - 2.7e-15 57.2 0.0 4.5e-15 56.4 0.0 1.4 1 0 0 1 1 1 1 CS domain TPR_2 PF07719.17 CBZ28751.1 - 6.8e-26 88.3 18.6 0.00073 19.5 0.4 8.9 9 0 0 9 9 9 6 Tetratricopeptide repeat TPR_1 PF00515.28 CBZ28751.1 - 6.2e-24 82.8 15.6 3.8e-05 23.3 0.3 7.7 8 0 0 8 8 8 6 Tetratricopeptide repeat TPR_8 PF13181.6 CBZ28751.1 - 2.2e-20 71.1 11.4 9e-05 22.4 0.1 7.8 8 0 0 8 8 7 5 Tetratricopeptide repeat TPR_12 PF13424.6 CBZ28751.1 - 3e-18 65.9 8.1 5.2e-09 36.3 0.0 6.3 5 1 1 6 6 5 4 Tetratricopeptide repeat TPR_7 PF13176.6 CBZ28751.1 - 2.4e-14 52.2 9.0 0.00056 19.8 0.2 7.2 7 0 0 7 7 6 2 Tetratricopeptide repeat TPR_19 PF14559.6 CBZ28751.1 - 6.6e-14 52.2 1.0 0.00054 20.4 0.1 6.0 6 1 1 7 7 6 2 Tetratricopeptide repeat TPR_16 PF13432.6 CBZ28751.1 - 1.9e-13 50.8 5.7 0.00082 20.0 0.0 5.6 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_14 PF13428.6 CBZ28751.1 - 7e-11 42.0 9.5 0.87 10.6 0.1 8.7 8 1 1 9 9 9 3 Tetratricopeptide repeat ANAPC3 PF12895.7 CBZ28751.1 - 1.2e-08 35.0 20.7 0.00093 19.4 0.2 4.2 3 1 1 4 4 4 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.6 CBZ28751.1 - 6.6e-08 32.7 13.1 0.0024 18.4 0.7 6.6 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_11 PF13414.6 CBZ28751.1 - 1.8e-07 30.7 8.8 0.021 14.5 0.4 6.2 5 2 2 7 7 6 2 TPR repeat TPR_15 PF13429.6 CBZ28751.1 - 4.6e-06 26.1 0.9 0.019 14.2 0.0 3.9 3 2 1 4 4 4 2 Tetratricopeptide repeat TPR_9 PF13371.6 CBZ28751.1 - 0.00016 21.7 2.5 0.054 13.6 0.0 4.0 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_17 PF13431.6 CBZ28751.1 - 0.00077 19.7 6.2 10 6.8 0.0 6.6 7 1 0 7 7 5 0 Tetratricopeptide repeat TPR_10 PF13374.6 CBZ28751.1 - 0.0011 18.7 8.6 0.98 9.4 0.5 6.0 7 0 0 7 7 7 1 Tetratricopeptide repeat SNAP PF14938.6 CBZ28751.1 - 0.0014 18.1 6.8 0.0014 18.1 2.5 2.8 2 1 0 2 2 2 1 Soluble NSF attachment protein, SNAP Sel1 PF08238.12 CBZ28751.1 - 0.0027 18.3 6.8 6.7 7.5 0.0 4.8 4 0 0 4 4 4 1 Sel1 repeat BTAD PF03704.17 CBZ28751.1 - 0.01 16.3 11.5 0.37 11.2 0.2 4.7 4 2 1 5 5 5 0 Bacterial transcriptional activator domain Fis1_TPR_C PF14853.6 CBZ28751.1 - 0.04 14.0 14.1 3.7 7.7 0.1 6.1 6 0 0 6 6 6 0 Fis1 C-terminal tetratricopeptide repeat DUF3856 PF12968.7 CBZ28751.1 - 0.084 12.9 1.8 0.63 10.1 0.2 2.9 3 0 0 3 3 3 0 Domain of Unknown Function (DUF3856) TPR_3 PF07720.12 CBZ28751.1 - 9.9 6.3 11.3 4.7 7.3 0.1 5.1 7 0 0 7 7 6 0 Tetratricopeptide repeat GrpE PF01025.19 CBZ28753.1 - 9.2e-42 142.5 2.6 1.1e-41 142.2 2.6 1.2 1 0 0 1 1 1 1 GrpE MIP-T3_C PF17749.1 CBZ28753.1 - 0.055 13.4 0.8 0.088 12.8 0.8 1.3 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 C-terminal region GrpE PF01025.19 CBZ28754.1 - 2.7e-34 118.2 0.4 3.5e-34 117.9 0.4 1.1 1 0 0 1 1 1 1 GrpE GvpL_GvpF PF06386.11 CBZ28756.1 - 0.058 13.3 0.7 0.08 12.9 0.7 1.2 1 0 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF DJ-1_PfpI PF01965.24 CBZ28757.1 - 2.3e-37 128.3 0.4 2.7e-37 128.1 0.4 1.1 1 0 0 1 1 1 1 DJ-1/PfpI family Arm PF00514.23 CBZ28758.1 - 5.4e-20 70.7 20.2 0.01 15.9 0.0 11.8 12 0 0 12 12 12 5 Armadillo/beta-catenin-like repeat Atx10homo_assoc PF09759.9 CBZ28758.1 - 2.1e-17 63.0 12.7 0.0036 17.3 0.0 8.5 3 3 5 9 9 9 6 Spinocerebellar ataxia type 10 protein domain HEAT_2 PF13646.6 CBZ28758.1 - 3.4e-07 30.6 7.3 0.0073 16.7 0.3 5.4 4 1 1 5 5 5 2 HEAT repeats HEAT_EZ PF13513.6 CBZ28758.1 - 0.00026 21.4 11.4 0.64 10.6 0.4 5.6 4 3 0 4 4 4 2 HEAT-like repeat DOG1 PF14144.6 CBZ28758.1 - 0.0037 17.5 2.8 0.31 11.3 0.0 3.7 3 1 0 3 3 3 1 Seed dormancy control WAPL PF07814.13 CBZ28758.1 - 8.1 5.1 10.7 1.2 7.8 0.0 3.9 3 1 2 5 5 5 0 Wings apart-like protein regulation of heterochromatin Choline_sulf_C PF12411.8 CBZ28759.1 - 0.23 11.3 1.4 15 5.5 0.0 2.9 3 0 0 3 3 3 0 Choline sulfatase enzyme C terminal Pkinase PF00069.25 CBZ28762.1 - 3.8e-70 236.3 0.0 7.3e-70 235.3 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ28762.1 - 2.2e-31 109.1 0.0 3.5e-31 108.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase PH PF00169.29 CBZ28762.1 - 2.7e-05 24.6 0.1 7.2e-05 23.3 0.1 1.7 1 0 0 1 1 1 1 PH domain Kinase-like PF14531.6 CBZ28762.1 - 0.0002 20.8 0.0 0.00048 19.5 0.0 1.6 1 1 0 1 1 1 1 Kinase-like APH PF01636.23 CBZ28762.1 - 0.025 14.5 0.0 0.053 13.4 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.14 CBZ28762.1 - 0.033 13.5 0.0 0.073 12.4 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family PH_9 PF15410.6 CBZ28762.1 - 0.04 14.3 0.6 27 5.1 0.1 3.2 2 1 0 2 2 2 0 Pleckstrin homology domain GH97_C PF14509.6 CBZ28762.1 - 0.12 12.6 0.0 0.49 10.7 0.0 2.0 2 0 0 2 2 2 0 Glycosyl-hydrolase 97 C-terminal, oligomerisation FeoB_C PF07664.12 CBZ28763.1 - 0.05 13.3 0.8 0.17 11.6 0.8 1.9 1 1 0 1 1 1 0 Ferrous iron transport protein B C terminus HRG PF16954.5 CBZ28764.1 - 0.036 14.5 0.3 0.036 14.5 0.3 2.5 2 1 0 2 2 2 0 Haem-transporter, endosomal/lysosomal, haem-responsive gene CrgA PF06781.12 CBZ28764.1 - 0.1 12.6 0.1 0.23 11.5 0.1 1.6 1 0 0 1 1 1 0 Cell division protein CrgA Methyltransf_PK PF05891.12 CBZ28765.1 - 7.4e-65 218.5 0.0 9.1e-65 218.2 0.0 1.0 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase Methyltransf_25 PF13649.6 CBZ28765.1 - 7e-12 45.9 0.0 1.1e-11 45.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CBZ28765.1 - 3.1e-11 43.8 0.0 4.6e-11 43.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 CBZ28765.1 - 3.1e-06 27.1 0.0 5.1e-06 26.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CBZ28765.1 - 1e-05 25.4 0.0 3.8e-05 23.5 0.0 1.6 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 CBZ28765.1 - 1.5e-05 25.7 0.0 2.6e-05 24.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 CBZ28765.1 - 3.7e-05 23.3 0.0 6.2e-05 22.6 0.0 1.3 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_2 PF00891.18 CBZ28765.1 - 7.7e-05 22.1 0.0 0.0001 21.7 0.0 1.3 1 1 0 1 1 1 1 O-methyltransferase domain DUF4407 PF14362.6 CBZ28766.1 - 0.41 9.9 9.1 0.12 11.7 1.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Fib_alpha PF08702.10 CBZ28766.1 - 1.6 8.9 9.2 0.43 10.8 2.9 2.5 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family DUF29 PF01724.16 CBZ28766.1 - 4.4 7.5 7.7 0.61 10.3 0.2 2.9 3 0 0 3 3 3 0 Domain of unknown function DUF29 DUF724 PF05266.14 CBZ28766.1 - 5.7 6.7 9.3 4.2 7.2 0.8 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF724) Prefoldin_2 PF01920.20 CBZ28767.1 - 2.5e-07 30.6 1.7 2.5e-07 30.6 1.7 1.7 1 1 0 1 1 1 1 Prefoldin subunit UPF0242 PF06785.11 CBZ28767.1 - 0.0088 16.2 3.3 0.01 15.9 3.3 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0242) N-terminus DUF2642 PF10842.8 CBZ28767.1 - 0.031 14.1 0.0 0.063 13.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2642) Med30 PF11315.8 CBZ28767.1 - 0.091 13.0 5.4 0.28 11.4 5.4 1.7 1 1 0 1 1 1 0 Mediator complex subunit 30 MMR_HSR1 PF01926.23 CBZ28768.1 - 5.3e-07 29.7 0.0 0.00014 21.9 0.0 3.2 2 1 0 2 2 2 1 50S ribosome-binding GTPase ATP_bind_1 PF03029.17 CBZ28768.1 - 3.2e-05 23.9 0.0 0.00037 20.4 0.0 2.4 3 0 0 3 3 3 1 Conserved hypothetical ATP binding protein GTP_EFTU PF00009.27 CBZ28768.1 - 0.00028 20.5 0.0 0.00054 19.6 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.18 CBZ28768.1 - 0.00039 20.0 0.1 0.27 10.7 0.0 2.8 3 0 0 3 3 3 2 Ferrous iron transport protein B Dynamin_N PF00350.23 CBZ28768.1 - 0.0013 18.8 0.0 0.056 13.5 0.0 2.6 2 1 0 2 2 2 1 Dynamin family RsgA_GTPase PF03193.16 CBZ28768.1 - 0.033 14.1 0.0 0.52 10.2 0.0 2.7 3 0 0 3 3 3 0 RsgA GTPase Amastin PF07344.11 CBZ28769.1 - 6.2e-44 149.6 8.7 7.3e-44 149.3 8.7 1.1 1 0 0 1 1 1 1 Amastin surface glycoprotein Amastin PF07344.11 CBZ28770.1 - 7.7e-44 149.3 8.4 9.1e-44 149.0 8.4 1.1 1 0 0 1 1 1 1 Amastin surface glycoprotein Amastin PF07344.11 CBZ28771.1 - 1.3e-40 138.8 4.6 1.7e-40 138.4 4.6 1.1 1 0 0 1 1 1 1 Amastin surface glycoprotein Yip1 PF04893.17 CBZ28771.1 - 0.0089 15.8 5.4 0.0089 15.8 5.4 2.0 2 0 0 2 2 2 1 Yip1 domain Claudin_2 PF13903.6 CBZ28771.1 - 0.068 12.9 10.6 0.029 14.1 6.6 2.2 2 1 1 3 3 3 0 PMP-22/EMP/MP20/Claudin tight junction DUF3951 PF13131.6 CBZ28771.1 - 3.1 8.1 10.9 1 9.6 0.2 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3951) PfkB PF00294.24 CBZ28772.1 - 1.8e-58 198.2 0.2 2.3e-58 197.9 0.2 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase DAGK_cat PF00781.24 CBZ28772.1 - 0.11 12.1 0.0 0.33 10.6 0.0 1.7 1 0 0 1 1 1 0 Diacylglycerol kinase catalytic domain PfkB PF00294.24 CBZ28773.1 - 5.4e-28 98.2 0.2 6.6e-28 97.9 0.2 1.1 1 0 0 1 1 1 1 pfkB family carbohydrate kinase HECT PF00632.25 CBZ28775.1 - 4.4e-78 262.9 0.0 6.8e-78 262.3 0.0 1.3 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) PSK_trans_fac PF07704.11 CBZ28775.1 - 0.36 11.6 4.0 2.1 9.2 4.0 2.4 1 0 0 1 1 1 0 Rv0623-like transcription factor DUF2894 PF11445.8 CBZ28776.1 - 3.5 8.1 7.3 1.8 9.0 0.3 3.2 4 0 0 4 4 4 0 Protein of unknown function (DUF2894) DUF4139 PF13598.6 CBZ28777.1 - 8.3e-46 156.3 0.0 1.4e-45 155.6 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4139) DUF4140 PF13600.6 CBZ28777.1 - 1.7e-05 25.2 6.5 0.0004 20.8 0.9 3.2 3 0 0 3 3 3 1 N-terminal domain of unknown function (DUF4140) Sugarporin_N PF11471.8 CBZ28777.1 - 0.039 13.9 0.8 0.13 12.2 0.8 2.0 1 0 0 1 1 1 0 Maltoporin periplasmic N-terminal extension PP-binding PF00550.25 CBZ28777.1 - 0.041 14.2 0.2 0.5 10.8 0.1 2.3 2 0 0 2 2 2 0 Phosphopantetheine attachment site TPIP1 PF15338.6 CBZ28777.1 - 0.07 13.2 0.8 3.4 7.7 0.1 2.4 2 0 0 2 2 2 0 p53-regulated apoptosis-inducing protein 1 Cob_adeno_trans PF01923.18 CBZ28777.1 - 0.07 13.3 0.5 31 4.7 0.0 3.1 3 0 0 3 3 3 0 Cobalamin adenosyltransferase Matrilin_ccoil PF10393.9 CBZ28777.1 - 2.9 7.8 6.5 4.5 7.2 0.5 2.6 2 0 0 2 2 2 0 Trimeric coiled-coil oligomerisation domain of matrilin GCP_C_terminal PF04130.13 CBZ28778.1 - 4.1e-22 79.0 0.0 6.8e-22 78.3 0.0 1.4 1 1 0 1 1 1 1 Gamma tubulin complex component C-terminal GCP_N_terminal PF17681.1 CBZ28778.1 - 4.4e-05 23.3 0.0 0.00034 20.3 0.0 2.0 1 1 0 1 1 1 1 Gamma tubulin complex component N-terminal RWP-RK PF02042.15 CBZ28778.1 - 0.045 13.7 0.0 0.13 12.3 0.0 1.7 1 0 0 1 1 1 0 RWP-RK domain WD40 PF00400.32 CBZ28779.1 - 6.8e-13 48.9 13.2 6.7e-06 26.8 0.8 5.6 5 0 0 5 5 5 3 WD domain, G-beta repeat CAF1C_H4-bd PF12265.8 CBZ28779.1 - 1.2e-09 38.3 0.0 2.3e-09 37.3 0.0 1.5 1 0 0 1 1 1 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex ANAPC4_WD40 PF12894.7 CBZ28779.1 - 1.6e-05 25.1 0.0 0.79 10.1 0.0 3.6 3 1 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 CBZ28779.1 - 0.22 10.4 0.1 2.3 7.1 0.0 2.4 2 1 1 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein PAX PF00292.18 CBZ28780.1 - 0.088 12.7 0.0 0.16 11.9 0.0 1.4 1 0 0 1 1 1 0 'Paired box' domain MAM33 PF02330.16 CBZ28781.1 - 2.2e-30 106.2 2.8 1.4e-26 93.7 1.9 2.1 1 1 1 2 2 2 2 Mitochondrial glycoprotein ABM PF03992.16 CBZ28781.1 - 0.079 13.1 0.1 0.43 10.7 0.0 2.2 3 0 0 3 3 3 0 Antibiotic biosynthesis monooxygenase APG5 PF04106.12 CBZ28782.1 - 0.00075 19.2 0.0 0.0079 15.8 0.0 2.1 2 0 0 2 2 2 1 Autophagy protein Apg5 DUF1214 PF06742.11 CBZ28783.1 - 0.14 12.6 0.1 0.27 11.7 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1214) Pkinase PF00069.25 CBZ28784.1 - 1.2e-35 123.1 0.0 5.7e-15 55.4 0.0 3.1 3 0 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ28784.1 - 4.8e-22 78.5 0.0 3.9e-13 49.3 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.23 CBZ28784.1 - 0.00012 22.1 2.6 0.00038 20.4 1.4 2.3 2 1 0 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.6 CBZ28784.1 - 0.074 12.3 0.0 0.52 9.6 0.0 2.0 2 0 0 2 2 2 0 Kinase-like Ufd2P_core PF10408.9 CBZ28785.1 - 2.4e-94 317.2 0.0 3.7e-94 316.5 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin elongating factor core Thioredoxin PF00085.20 CBZ28785.1 - 3e-21 75.3 0.0 6.6e-21 74.2 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin OST3_OST6 PF04756.13 CBZ28785.1 - 9.8e-07 28.4 0.0 1.6e-06 27.7 0.0 1.3 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin_2 PF13098.6 CBZ28785.1 - 1.7e-05 25.2 0.2 6.4e-05 23.4 0.2 1.9 1 0 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 CBZ28785.1 - 0.002 18.4 0.0 0.24 11.7 0.0 2.6 1 1 1 2 2 2 1 Thioredoxin-like Thioredoxin_9 PF14595.6 CBZ28785.1 - 0.0023 17.7 0.0 0.0061 16.3 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin U-box PF04564.15 CBZ28785.1 - 0.0025 18.0 0.0 0.022 14.9 0.0 2.7 2 0 0 2 2 2 1 U-box domain BUD22 PF09073.10 CBZ28785.1 - 0.0055 16.1 0.4 0.0087 15.4 0.4 1.2 1 0 0 1 1 1 1 BUD22 Thioredoxin_7 PF13899.6 CBZ28785.1 - 0.01 16.0 0.1 0.048 13.8 0.1 2.2 1 0 0 1 1 1 1 Thioredoxin-like AhpC-TSA PF00578.21 CBZ28785.1 - 0.028 14.3 0.1 0.1 12.5 0.1 1.9 1 1 1 2 2 2 0 AhpC/TSA family DnaJ PF00226.31 CBZ28787.1 - 2.2e-20 72.5 0.5 4.1e-20 71.7 0.5 1.5 1 0 0 1 1 1 1 DnaJ domain MSA-2c PF12238.8 CBZ28787.1 - 0.031 14.3 1.0 0.059 13.4 1.0 1.4 1 0 0 1 1 1 0 Merozoite surface antigen 2c Joubert PF15392.6 CBZ28787.1 - 2 8.1 6.3 3 7.5 6.3 1.3 1 0 0 1 1 1 0 Joubert syndrome-associated DUF4680 PF15730.5 CBZ28787.1 - 3.2 8.1 8.8 3.6 7.9 6.5 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4680) zf-CCHC_2 PF13696.6 CBZ28788.1 - 1.6 8.6 4.2 1.4 8.8 1.4 2.3 2 0 0 2 2 2 0 Zinc knuckle Mito_carr PF00153.27 CBZ28789.1 - 6.5e-47 157.4 2.5 1.4e-15 56.9 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein RF-1 PF00472.20 CBZ28790.1 - 4.2e-15 55.7 0.0 9.3e-15 54.6 0.0 1.6 1 1 0 1 1 1 1 RF-1 domain TRF PF08558.10 CBZ28790.1 - 0.02 14.5 0.0 0.029 14.0 0.0 1.1 1 0 0 1 1 1 0 Telomere repeat binding factor (TRF) MRP-S28 PF10213.9 CBZ28790.1 - 0.13 12.6 0.0 0.17 12.3 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial ribosomal subunit protein Sdh5 PF03937.16 CBZ28791.1 - 1.2e-19 70.0 1.0 2.1e-19 69.2 1.0 1.5 1 0 0 1 1 1 1 Flavinator of succinate dehydrogenase IQ PF00612.27 CBZ28792.1 - 1.4e-07 30.7 20.3 0.0068 16.1 0.5 5.9 5 0 0 5 5 5 5 IQ calmodulin-binding motif WW PF00397.26 CBZ28793.1 - 4.9e-10 39.3 2.2 9e-10 38.5 2.2 1.5 1 0 0 1 1 1 1 WW domain ATG16 PF08614.11 CBZ28793.1 - 0.00023 21.5 0.7 0.00023 21.5 0.7 2.2 2 0 0 2 2 2 1 Autophagy protein 16 (ATG16) DREV PF05219.12 CBZ28794.1 - 1.2e-63 214.7 0.0 1.4e-63 214.5 0.0 1.0 1 0 0 1 1 1 1 DREV methyltransferase Methyltransf_23 PF13489.6 CBZ28794.1 - 2.2e-12 47.1 0.0 3e-12 46.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CBZ28794.1 - 3.2e-12 47.0 0.0 5.7e-12 46.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CBZ28794.1 - 4e-12 46.6 0.0 7.3e-12 45.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CBZ28794.1 - 2.7e-09 37.6 0.0 5.4e-09 36.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CBZ28794.1 - 2.8e-05 24.0 0.1 0.00021 21.1 0.1 2.0 1 1 0 1 1 1 1 Methyltransferase domain CheR PF01739.18 CBZ28794.1 - 0.0091 15.5 0.0 0.015 14.8 0.0 1.3 1 0 0 1 1 1 1 CheR methyltransferase, SAM binding domain RrnaAD PF00398.20 CBZ28794.1 - 0.049 12.7 0.0 0.069 12.2 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase NodS PF05401.11 CBZ28794.1 - 0.051 13.2 0.0 0.077 12.6 0.0 1.2 1 0 0 1 1 1 0 Nodulation protein S (NodS) RRM_1 PF00076.22 CBZ28795.1 - 1.6e-23 82.3 0.0 2e-09 37.1 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RNA_bind PF08675.11 CBZ28795.1 - 0.0011 18.9 0.0 0.12 12.4 0.0 2.9 3 0 0 3 3 3 1 RNA binding domain DUF4523 PF15023.6 CBZ28795.1 - 0.0087 15.9 0.0 0.033 14.0 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF4523) Nup35_RRM_2 PF14605.6 CBZ28795.1 - 0.0093 16.0 0.0 5.6 7.0 0.0 2.4 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif Arm PF00514.23 CBZ28796.1 - 8.9e-69 225.6 19.5 4.2e-10 39.3 0.0 8.8 9 0 0 9 9 9 8 Armadillo/beta-catenin-like repeat Arm_3 PF16186.5 CBZ28796.1 - 6.4e-15 54.5 0.0 2.1e-14 52.8 0.0 1.9 2 0 0 2 2 2 1 Atypical Arm repeat HEAT_2 PF13646.6 CBZ28796.1 - 1e-14 54.7 2.2 0.001 19.4 0.1 5.8 2 1 4 7 7 7 5 HEAT repeats HEAT_EZ PF13513.6 CBZ28796.1 - 2.5e-14 53.4 11.6 0.00015 22.2 0.2 6.9 5 2 3 8 8 8 3 HEAT-like repeat HEAT PF02985.22 CBZ28796.1 - 4e-12 45.3 11.5 0.084 13.2 0.0 8.0 9 0 0 9 9 9 4 HEAT repeat Arm_2 PF04826.13 CBZ28796.1 - 0.0075 15.7 0.0 0.31 10.4 0.0 3.2 3 1 1 4 4 4 2 Armadillo-like DCB PF16213.5 CBZ28796.1 - 0.11 12.2 0.0 0.23 11.1 0.0 1.6 1 0 0 1 1 1 0 Dimerisation and cyclophilin-binding domain of Mon2 MA3 PF02847.17 CBZ28799.1 - 5e-08 32.9 0.1 1.1e-07 31.9 0.1 1.6 1 0 0 1 1 1 1 MA3 domain DHHC PF01529.20 CBZ28801.1 - 1.4e-34 119.1 10.6 1.4e-34 119.1 10.6 1.8 2 0 0 2 2 2 1 DHHC palmitoyltransferase TMEM107 PF14995.6 CBZ28802.1 - 6.9e-31 107.3 6.3 8.3e-31 107.0 6.3 1.1 1 0 0 1 1 1 1 Transmembrane protein Cupin_8 PF13621.6 CBZ28803.1 - 7.2e-19 68.5 0.0 4.1e-18 66.0 0.0 1.9 1 1 0 1 1 1 1 Cupin-like domain JmjC PF02373.22 CBZ28803.1 - 2.4e-10 40.8 0.2 4.6e-07 30.3 0.1 2.4 2 0 0 2 2 2 2 JmjC domain, hydroxylase Cupin_2 PF07883.11 CBZ28803.1 - 0.00055 19.6 0.3 0.012 15.3 0.1 2.4 2 0 0 2 2 2 1 Cupin domain Cupin_4 PF08007.12 CBZ28803.1 - 0.028 13.9 0.0 0.046 13.2 0.0 1.3 1 0 0 1 1 1 0 Cupin superfamily protein F-box-like PF12937.7 CBZ28803.1 - 0.42 10.5 8.5 0.06 13.2 3.1 2.6 2 1 0 2 2 2 0 F-box-like UCH PF00443.29 CBZ28804.1 - 4.3e-34 118.2 0.0 6.3e-34 117.6 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 CBZ28804.1 - 9.7e-07 28.7 0.5 0.0038 16.9 1.0 2.4 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 CBZ28804.1 - 1.3 9.5 11.9 0.31 11.4 4.1 3.7 3 1 0 3 3 3 0 Zn-finger in ubiquitin-hydrolases and other protein LSM PF01423.22 CBZ28805.1 - 9e-14 50.9 0.1 1e-13 50.7 0.1 1.1 1 0 0 1 1 1 1 LSM domain AAA_28 PF13521.6 CBZ28806.1 - 4.5e-18 66.0 0.0 8.1e-18 65.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain MeaB PF03308.16 CBZ28806.1 - 0.014 14.4 0.1 0.022 13.7 0.1 1.2 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_30 PF13604.6 CBZ28806.1 - 0.021 14.5 0.0 0.06 13.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain DAP3 PF10236.9 CBZ28806.1 - 0.08 12.1 0.0 0.13 11.4 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 zf-C3HC4_3 PF13920.6 CBZ28807.1 - 7.9e-09 35.2 12.9 7.9e-09 35.2 12.9 3.6 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 CBZ28807.1 - 0.00013 21.7 13.7 0.00013 21.7 13.7 3.1 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 CBZ28807.1 - 0.014 15.2 12.9 0.014 15.2 12.9 3.1 4 0 0 4 4 4 0 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 CBZ28807.1 - 0.018 15.4 14.6 0.018 15.4 14.6 3.5 2 1 1 3 3 3 0 Ring finger domain Rtf2 PF04641.12 CBZ28807.1 - 1.9 7.8 6.4 7.9 5.8 1.5 2.5 2 0 0 2 2 2 0 Rtf2 RING-finger EF-hand_7 PF13499.6 CBZ28808.1 - 1.9e-05 25.0 1.4 0.0031 17.9 0.1 2.2 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 CBZ28808.1 - 0.0051 16.6 0.1 0.019 14.9 0.1 2.0 1 0 0 1 1 1 1 EF-hand domain EF-hand_1 PF00036.32 CBZ28808.1 - 0.052 13.1 0.0 0.12 12.0 0.0 1.7 1 0 0 1 1 1 0 EF hand EF-hand_5 PF13202.6 CBZ28808.1 - 0.096 12.2 0.1 0.2 11.2 0.1 1.6 1 0 0 1 1 1 0 EF hand Phos_pyr_kin PF08543.12 CBZ28809.1 - 1.9e-16 60.2 0.0 2.5e-16 59.8 0.0 1.2 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase PfkB PF00294.24 CBZ28809.1 - 3.9e-10 39.5 1.4 3.9e-09 36.2 0.0 2.2 2 0 0 2 2 2 1 pfkB family carbohydrate kinase Acetyltransf_7 PF13508.7 CBZ28810.1 - 2e-05 24.9 0.0 0.0016 18.8 0.0 2.3 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 CBZ28810.1 - 0.00018 21.7 0.0 0.00065 19.9 0.0 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family FR47 PF08445.10 CBZ28810.1 - 0.00066 19.6 0.1 0.032 14.2 0.0 2.3 2 0 0 2 2 2 1 FR47-like protein Acetyltransf_9 PF13527.7 CBZ28810.1 - 0.0027 17.8 0.0 0.052 13.6 0.0 2.2 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 CBZ28810.1 - 0.0034 17.3 0.0 0.035 14.0 0.0 2.1 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain CENP-F_leu_zip PF10473.9 CBZ28812.1 - 0.00042 20.3 1.0 0.00042 20.3 1.0 3.7 4 1 0 4 4 4 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 HAUS-augmin3 PF14932.6 CBZ28812.1 - 0.0097 15.5 4.3 0.0097 15.5 4.3 3.8 3 1 1 4 4 4 1 HAUS augmin-like complex subunit 3 Seryl_tRNA_N PF02403.22 CBZ28812.1 - 0.023 14.9 1.5 0.023 14.9 1.5 4.3 4 1 0 4 4 4 0 Seryl-tRNA synthetase N-terminal domain TMF_DNA_bd PF12329.8 CBZ28812.1 - 0.03 14.3 0.3 0.03 14.3 0.3 4.8 5 0 0 5 5 5 0 TATA element modulatory factor 1 DNA binding 3HCDH_N PF02737.18 CBZ28812.1 - 0.39 10.6 3.9 1.2 9.0 3.9 1.9 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DUF5320 PF17253.2 CBZ28812.1 - 0.82 10.8 6.6 57 4.9 0.1 4.1 3 1 1 4 4 4 0 Family of unknown function (DUF5320) AAA_13 PF13166.6 CBZ28812.1 - 2.5 6.7 12.7 0.25 9.9 7.8 1.7 2 0 0 2 2 2 0 AAA domain Takusan PF04822.13 CBZ28812.1 - 4.4 7.2 7.9 0.15 11.9 0.3 2.6 3 0 0 3 3 3 0 Takusan NPV_P10 PF05531.12 CBZ28812.1 - 5.4 7.6 12.6 32 5.1 0.5 4.7 3 2 0 3 3 3 0 Nucleopolyhedrovirus P10 protein Clathrin PF00637.20 CBZ28813.1 - 2.8e-09 37.0 0.1 5.7e-07 29.5 0.4 2.4 2 0 0 2 2 2 1 Region in Clathrin and VPS zf-C3HC4_2 PF13923.6 CBZ28813.1 - 5.6e-05 22.9 1.4 0.00019 21.2 1.4 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3H2C3 PF17122.5 CBZ28813.1 - 0.00041 20.3 2.5 0.001 19.0 2.5 1.7 1 0 0 1 1 1 1 Zinc-finger zf-C3HC4 PF00097.25 CBZ28813.1 - 0.0068 16.3 0.5 0.019 14.8 0.5 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 CBZ28813.1 - 0.012 15.9 0.4 0.04 14.2 0.4 1.9 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-RING_2 PF13639.6 CBZ28813.1 - 0.018 15.4 1.2 0.059 13.7 1.2 2.0 1 0 0 1 1 1 0 Ring finger domain zf-RING_11 PF17123.5 CBZ28813.1 - 0.12 12.2 2.9 0.57 10.0 2.9 2.3 1 0 0 1 1 1 0 RING-like zinc finger zf-RING_5 PF14634.6 CBZ28813.1 - 0.13 12.2 3.4 0.07 13.1 0.4 2.2 2 0 0 2 2 2 0 zinc-RING finger domain zf-RING_UBOX PF13445.6 CBZ28813.1 - 0.84 9.7 3.6 0.33 11.0 0.6 1.9 2 0 0 2 2 2 0 RING-type zinc-finger zf-RING-like PF08746.11 CBZ28813.1 - 3.2 8.2 7.7 0.1 12.9 0.8 2.1 2 0 0 2 2 2 0 RING-like domain Zn_ribbon_17 PF17120.5 CBZ28813.1 - 4.2 7.1 8.5 0.16 11.6 0.3 2.8 3 0 0 3 3 3 0 Zinc-ribbon, C4HC2 type Brix PF04427.18 CBZ28814.1 - 1.4e-29 103.6 0.3 1.8e-29 103.2 0.3 1.2 1 0 0 1 1 1 1 Brix domain SNF2_N PF00176.23 CBZ28815.1 - 4.7e-42 144.0 0.0 7.7e-42 143.3 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 CBZ28815.1 - 4.6e-10 39.8 0.0 1e-09 38.7 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 CBZ28815.1 - 5.2e-05 23.3 0.0 0.00013 22.0 0.0 1.6 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 CBZ28815.1 - 0.015 14.5 0.0 0.025 13.8 0.0 1.2 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase ABC_tran PF00005.27 CBZ28817.1 - 2.3e-19 70.3 0.3 2.1e-12 47.8 0.4 3.1 2 1 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 CBZ28817.1 - 9.4e-09 35.5 0.4 0.00047 20.1 0.1 2.9 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 CBZ28817.1 - 6.5e-06 25.7 0.2 0.015 14.7 0.1 2.8 2 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 CBZ28817.1 - 0.0007 19.5 0.2 0.0029 17.5 0.1 1.9 2 0 0 2 2 2 1 RsgA GTPase IstB_IS21 PF01695.17 CBZ28817.1 - 0.0014 18.4 0.8 1.9 8.2 0.0 3.1 3 0 0 3 3 3 2 IstB-like ATP binding protein AAA_16 PF13191.6 CBZ28817.1 - 0.0027 18.1 0.0 0.08 13.3 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain AAA_29 PF13555.6 CBZ28817.1 - 0.0046 16.7 0.0 0.0098 15.6 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_28 PF13521.6 CBZ28817.1 - 0.0048 17.2 0.9 0.1 12.8 0.9 2.5 1 1 0 1 1 1 1 AAA domain AAA_24 PF13479.6 CBZ28817.1 - 0.031 14.0 0.0 0.05 13.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 CBZ28817.1 - 0.049 14.1 0.0 0.08 13.4 0.0 1.2 1 0 0 1 1 1 0 AAA domain Dynamin_N PF00350.23 CBZ28817.1 - 0.096 12.7 0.1 0.16 12.0 0.1 1.3 1 0 0 1 1 1 0 Dynamin family AAA_19 PF13245.6 CBZ28817.1 - 0.18 12.1 0.6 5.1 7.4 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_15 PF13175.6 CBZ28817.1 - 0.19 11.4 0.0 0.25 11.0 0.0 1.1 1 0 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 CBZ28817.1 - 0.43 10.9 1.4 2.3 8.5 0.1 2.3 2 0 0 2 2 2 0 AAA domain RabGAP-TBC PF00566.18 CBZ28819.1 - 5.8e-36 124.2 0.2 1e-35 123.3 0.2 1.4 1 0 0 1 1 1 1 Rab-GTPase-TBC domain RIO1 PF01163.22 CBZ28820.1 - 2.3e-45 154.5 0.0 4.1e-45 153.7 0.0 1.3 1 0 0 1 1 1 1 RIO1 family Rio2_N PF09202.11 CBZ28820.1 - 4.5e-33 113.3 0.3 1.2e-31 108.7 0.3 2.4 2 0 0 2 2 2 1 Rio2, N-terminal APH PF01636.23 CBZ28820.1 - 3.1e-09 37.1 0.0 1e-05 25.6 0.0 2.4 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 CBZ28820.1 - 0.012 15.0 0.0 0.012 15.0 0.0 3.1 4 1 0 4 4 4 0 Lipopolysaccharide kinase (Kdo/WaaP) family PSP1 PF04468.12 CBZ28821.1 - 1e-11 44.9 0.1 1.7e-11 44.2 0.1 1.4 1 0 0 1 1 1 1 PSP1 C-terminal conserved region Peptidase_M20 PF01546.28 CBZ28822.1 - 9.1e-30 103.9 0.1 1.1e-29 103.6 0.1 1.1 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 CBZ28822.1 - 6.8e-07 29.2 0.0 1.5e-06 28.1 0.0 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 CBZ28822.1 - 0.024 14.3 0.0 0.041 13.6 0.0 1.3 1 0 0 1 1 1 0 Peptidase family M28 PLAC8 PF04749.17 CBZ28823.1 - 1.1e-15 58.4 12.8 1.5e-15 58.0 12.8 1.2 1 0 0 1 1 1 1 PLAC8 family WD40 PF00400.32 CBZ28824.1 - 2.7e-18 66.0 0.5 0.00092 20.0 0.0 6.8 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBZ28824.1 - 0.013 15.8 0.0 5.1 7.5 0.0 2.5 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 CBZ28824.1 - 0.021 13.5 0.3 5.1 5.6 0.1 2.4 2 1 1 3 3 3 0 Nucleoporin Nup120/160 PLAC8 PF04749.17 CBZ28825.1 - 1e-12 48.9 24.6 1.3e-12 48.6 24.6 1.1 1 0 0 1 1 1 1 PLAC8 family PLAC8 PF04749.17 CBZ28826.1 - 1.1e-13 51.9 24.8 1.5e-13 51.6 24.8 1.1 1 0 0 1 1 1 1 PLAC8 family Kinesin PF00225.23 CBZ28828.1 - 1.5e-81 273.9 0.0 1.5e-81 273.9 0.0 1.5 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 CBZ28828.1 - 2.8e-18 66.3 0.0 5.7e-18 65.3 0.0 1.5 1 0 0 1 1 1 1 Microtubule binding Alveol-reg_P311 PF11092.8 CBZ28828.1 - 0.032 14.4 0.1 0.089 12.9 0.1 1.7 1 0 0 1 1 1 0 Neuronal protein 3.1 (p311) S1-P1_nuclease PF02265.16 CBZ28829.1 - 3e-60 204.2 0.0 3.4e-60 204.0 0.0 1.0 1 0 0 1 1 1 1 S1/P1 Nuclease Muskelin_N PF06588.11 CBZ28829.1 - 0.12 12.3 0.1 0.18 11.7 0.1 1.3 1 0 0 1 1 1 0 Muskelin N-terminus S1-P1_nuclease PF02265.16 CBZ28830.1 - 5e-58 196.9 0.0 5.7e-58 196.7 0.0 1.0 1 0 0 1 1 1 1 S1/P1 Nuclease DUF2924 PF11149.8 CBZ28830.1 - 0.15 12.4 0.0 0.31 11.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2924) PseudoU_synth_2 PF00849.22 CBZ28831.1 - 7.1e-34 117.2 0.0 8.4e-33 113.7 0.0 2.0 1 1 0 1 1 1 1 RNA pseudouridylate synthase Rad17 PF03215.15 CBZ28832.1 - 3.1e-05 24.0 0.0 5.5e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 Rad17 P-loop domain RuvB_N PF05496.12 CBZ28832.1 - 0.059 13.1 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA PF00004.29 CBZ28832.1 - 0.11 12.9 0.0 0.35 11.3 0.0 1.8 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 CBZ28832.1 - 0.12 12.8 1.3 1.2 9.5 0.0 2.9 3 0 0 3 3 3 0 AAA ATPase domain Flavoprotein PF02441.19 CBZ28833.1 - 2.8e-48 163.6 0.3 4.3e-44 150.0 0.1 2.1 2 0 0 2 2 2 2 Flavoprotein PseudoU_synth_1 PF01416.20 CBZ28834.1 - 1.5e-26 93.0 0.0 9.7e-25 87.1 0.0 2.5 2 0 0 2 2 2 2 tRNA pseudouridine synthase Pkinase PF00069.25 CBZ28835.1 - 4.8e-32 111.4 0.0 6.6e-12 45.4 0.1 3.2 3 0 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ28835.1 - 2e-14 53.5 0.0 6e-06 25.7 0.2 3.1 3 0 0 3 3 3 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 CBZ28835.1 - 0.008 15.0 0.0 0.021 13.6 0.0 1.6 1 0 0 1 1 1 1 Fungal protein kinase DUF1796 PF08795.10 CBZ28836.1 - 4.2e-69 231.8 0.0 7.5e-69 231.0 0.0 1.4 1 0 0 1 1 1 1 Putative papain-like cysteine peptidase (DUF1796) PH PF00169.29 CBZ28837.1 - 4.7e-07 30.3 4.5 0.00038 20.9 0.7 2.8 2 1 0 2 2 2 2 PH domain Kelch_4 PF13418.6 CBZ28837.1 - 1.5e-06 28.1 3.3 0.079 13.0 0.0 5.0 5 0 0 5 5 5 2 Galactose oxidase, central domain Kelch_3 PF13415.6 CBZ28837.1 - 0.0053 17.0 1.3 56 4.2 0.0 5.7 6 0 0 6 6 6 0 Galactose oxidase, central domain Kelch_1 PF01344.25 CBZ28837.1 - 3.7 7.2 10.7 1.9 8.1 0.1 4.1 6 0 0 6 6 6 0 Kelch motif Actin PF00022.19 CBZ28839.1 - 0.0077 14.9 0.0 0.014 14.1 0.0 1.3 1 0 0 1 1 1 1 Actin Nop14 PF04147.12 CBZ28839.1 - 0.099 10.8 4.5 0.15 10.3 4.5 1.1 1 0 0 1 1 1 0 Nop14-like family Apt1 PF10351.9 CBZ28839.1 - 0.48 9.2 7.0 0.7 8.7 7.0 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain Macoilin PF09726.9 CBZ28839.1 - 7.8 4.9 10.1 14 4.1 10.1 1.3 1 0 0 1 1 1 0 Macoilin family NAD_binding_6 PF08030.12 CBZ28840.1 - 4.3e-15 56.2 0.0 8.3e-08 32.5 0.0 2.3 2 0 0 2 2 2 2 Ferric reductase NAD binding domain Ferric_reduct PF01794.19 CBZ28840.1 - 5e-15 55.7 11.1 5e-15 55.7 11.1 2.9 3 1 0 3 3 3 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.12 CBZ28840.1 - 3.9e-10 39.8 0.0 7.4e-10 38.9 0.0 1.5 1 0 0 1 1 1 1 FAD-binding domain FAD_binding_6 PF00970.24 CBZ28840.1 - 0.029 14.7 0.0 0.07 13.5 0.0 1.7 1 1 0 1 1 1 0 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.21 CBZ28840.1 - 0.055 14.1 0.0 1 10.0 0.0 2.4 2 0 0 2 2 2 0 Oxidoreductase NAD-binding domain TOBE_2 PF08402.10 CBZ28841.1 - 0.091 12.9 0.0 0.28 11.4 0.0 1.8 1 0 0 1 1 1 0 TOBE domain DUF1077 PF06417.12 CBZ28843.1 - 2.3e-35 121.2 0.8 2.7e-35 120.9 0.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1077) PqiA PF04403.13 CBZ28843.1 - 0.002 18.0 0.9 0.0025 17.7 0.9 1.1 1 0 0 1 1 1 1 Paraquat-inducible protein A DUF4064 PF13273.6 CBZ28843.1 - 0.018 15.3 0.4 0.029 14.6 0.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4064) ThrE PF06738.12 CBZ28843.1 - 0.032 13.6 0.5 0.061 12.7 0.5 1.6 1 1 0 1 1 1 0 Putative threonine/serine exporter PIG-U PF06728.13 CBZ28843.1 - 0.036 13.1 0.1 0.041 12.9 0.1 1.0 1 0 0 1 1 1 0 GPI transamidase subunit PIG-U Dynein_heavy PF03028.15 CBZ28843.1 - 0.11 12.6 0.1 0.21 11.7 0.1 1.5 1 1 0 1 1 1 0 Dynein heavy chain region D6 P-loop domain HSP33 PF01430.19 CBZ28844.1 - 2.5e-14 53.3 0.0 8.4e-08 31.9 0.0 2.2 2 0 0 2 2 2 2 Hsp33 protein CRAL_TRIO PF00650.20 CBZ28845.1 - 2.8e-19 69.4 0.0 3.5e-19 69.1 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.6 CBZ28845.1 - 0.00093 19.4 0.0 0.0013 18.8 0.0 1.2 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain DUF4350 PF14258.6 CBZ28846.1 - 0.0087 16.5 0.2 0.34 11.4 0.1 2.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4350) LCIB_C_CA PF18599.1 CBZ28846.1 - 0.057 12.7 0.2 0.13 11.6 0.2 1.5 1 0 0 1 1 1 0 Limiting CO2-inducible proteins B/C beta carbonyic anhydrases AAA_2 PF07724.14 CBZ28847.1 - 1.4e-07 31.8 0.0 2.2e-07 31.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) DUF2721 PF11026.8 CBZ28847.1 - 1.5e-05 24.9 1.9 4.6e-05 23.3 1.9 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF2721) AAA_22 PF13401.6 CBZ28847.1 - 2.1e-05 24.8 0.0 0.00017 21.9 0.0 2.4 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.14 CBZ28847.1 - 3.4e-05 23.9 0.0 9.8e-05 22.4 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA PF00004.29 CBZ28847.1 - 0.0022 18.4 0.0 0.0045 17.4 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 CBZ28847.1 - 0.0045 17.1 0.5 0.13 12.4 0.0 3.1 3 0 0 3 3 3 1 AAA domain AAA_16 PF13191.6 CBZ28847.1 - 0.037 14.4 0.3 2.6 8.4 0.0 3.2 3 1 0 3 3 3 0 AAA ATPase domain Mg_chelatase PF01078.21 CBZ28847.1 - 0.13 11.6 0.0 0.28 10.5 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI PaaX PF07848.12 CBZ28847.1 - 3.5 7.9 4.8 0.91 9.8 0.2 2.4 3 0 0 3 3 3 0 PaaX-like protein Ras PF00071.22 CBZ28848.1 - 3.1e-38 130.9 0.0 3.9e-38 130.6 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CBZ28848.1 - 2.4e-25 89.1 0.0 4e-25 88.4 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CBZ28848.1 - 3.1e-10 39.8 0.0 4.1e-10 39.4 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 CBZ28848.1 - 0.0013 18.7 0.1 0.31 10.9 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 CBZ28848.1 - 0.0014 18.6 0.0 0.0027 17.8 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 CBZ28848.1 - 0.002 17.5 0.0 0.0029 17.0 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region FeoB_N PF02421.18 CBZ28848.1 - 0.0023 17.5 0.1 2.3 7.7 0.0 2.3 2 0 0 2 2 2 2 Ferrous iron transport protein B Ribonuc_red_lgN PF00317.21 CBZ28848.1 - 0.037 14.0 0.0 0.079 13.0 0.0 1.5 1 0 0 1 1 1 0 Ribonucleotide reductase, all-alpha domain PduV-EutP PF10662.9 CBZ28848.1 - 0.053 13.3 0.0 0.1 12.4 0.0 1.4 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_16 PF13191.6 CBZ28848.1 - 0.059 13.8 0.1 0.11 12.9 0.1 1.7 1 1 0 1 1 1 0 AAA ATPase domain G-alpha PF00503.20 CBZ28848.1 - 0.2 10.8 0.0 13 4.8 0.0 2.3 1 1 1 2 2 2 0 G-protein alpha subunit ATG16 PF08614.11 CBZ28850.1 - 0.0039 17.4 18.0 0.027 14.7 4.2 2.3 2 0 0 2 2 2 2 Autophagy protein 16 (ATG16) Rootletin PF15035.6 CBZ28850.1 - 0.097 12.7 23.8 0.49 10.4 9.1 2.3 2 0 0 2 2 2 0 Ciliary rootlet component, centrosome cohesion Spc29 PF17082.5 CBZ28850.1 - 0.16 11.8 9.0 7.3 6.4 0.4 3.2 2 1 0 2 2 2 0 Spindle Pole Component 29 CENP-F_leu_zip PF10473.9 CBZ28850.1 - 2.9 7.9 23.8 0.84 9.6 8.2 2.6 2 1 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DivIC PF04977.15 CBZ28850.1 - 3.5 7.4 19.2 0.93 9.3 0.8 3.3 2 1 1 3 3 3 0 Septum formation initiator APG6_N PF17675.1 CBZ28850.1 - 3.6 8.1 21.8 3.1 8.3 1.8 2.4 2 0 0 2 2 2 0 Apg6 coiled-coil region DUF4407 PF14362.6 CBZ28850.1 - 6.6 6.0 10.8 6.8 5.9 3.3 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) RVT_3 PF13456.6 CBZ28852.1 - 0.12 12.2 0.0 0.22 11.3 0.0 1.4 1 0 0 1 1 1 0 Reverse transcriptase-like CLASP_N PF12348.8 CBZ28853.1 - 1.3e-11 44.5 1.7 1.9e-06 27.6 0.1 4.1 4 0 0 4 4 4 2 CLASP N terminal NUC173 PF08161.12 CBZ28853.1 - 0.022 14.4 2.3 0.44 10.2 0.1 4.1 5 0 0 5 5 5 0 NUC173 domain HEAT_2 PF13646.6 CBZ28853.1 - 0.024 15.0 13.9 0.65 10.4 0.1 6.8 7 1 1 8 8 8 0 HEAT repeats Cnd1 PF12717.7 CBZ28853.1 - 0.12 12.4 2.7 20 5.2 0.0 3.5 3 0 0 3 3 3 0 non-SMC mitotic condensation complex subunit 1 IFT46_B_C PF12317.8 CBZ28854.1 - 6.6e-79 264.5 0.1 8.1e-79 264.3 0.1 1.1 1 0 0 1 1 1 1 Intraflagellar transport complex B protein 46 C terminal NOA36 PF06524.12 CBZ28854.1 - 1.9 7.7 4.1 2.7 7.2 4.1 1.1 1 0 0 1 1 1 0 NOA36 protein Pkinase PF00069.25 CBZ28855.1 - 6.7e-31 107.6 0.0 1.7e-27 96.4 0.0 3.3 3 0 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ28855.1 - 9.5e-10 38.2 0.0 5e-06 26.0 0.0 3.0 2 1 0 3 3 3 2 Protein tyrosine kinase APH PF01636.23 CBZ28855.1 - 0.01 15.8 0.1 0.027 14.4 0.0 1.7 2 0 0 2 2 2 0 Phosphotransferase enzyme family DnaJ PF00226.31 CBZ28856.1 - 1.6e-20 72.9 0.2 4.1e-20 71.7 0.2 1.7 1 0 0 1 1 1 1 DnaJ domain TGT PF01702.18 CBZ28857.1 - 1.4e-127 425.7 0.1 1.2e-94 317.3 0.0 2.1 2 0 0 2 2 2 2 Queuine tRNA-ribosyltransferase ASH PF15780.5 CBZ28858.1 - 2.2e-55 184.9 40.9 9.3e-07 29.0 0.1 30.1 34 0 0 34 34 33 9 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin PapD-like PF14874.6 CBZ28858.1 - 4.3e-20 71.8 30.7 0.00033 20.8 0.1 15.0 18 0 0 18 18 17 5 Flagellar-associated PapD-like Motile_Sperm PF00635.26 CBZ28858.1 - 1.6e-12 47.2 12.7 0.068 13.0 0.0 12.5 17 0 0 17 17 15 2 MSP (Major sperm protein) domain DUF1573 PF07610.11 CBZ28858.1 - 2.3e-12 46.8 0.0 14 5.8 0.0 13.7 18 0 0 18 18 15 0 Protein of unknown function (DUF1573) MYCBPAP PF14646.6 CBZ28858.1 - 5.4e-07 28.9 0.0 4.2 6.2 0.0 7.1 9 0 0 9 9 9 1 MYCBP-associated protein family DUF5001 PF16392.5 CBZ28858.1 - 1.4e-05 24.9 0.8 13 5.8 0.0 6.6 7 0 0 7 7 6 0 Ig-like domain TMEM131_like PF12371.8 CBZ28858.1 - 0.00019 21.7 12.8 25 5.2 0.0 9.8 12 0 0 12 12 10 0 Transmembrane protein 131-like Trigger_C PF05698.14 CBZ28858.1 - 0.012 15.6 1.6 0.022 14.8 1.6 1.3 1 0 0 1 1 1 0 Bacterial trigger factor protein (TF) C-terminus Zeta_toxin PF06414.12 CBZ28858.1 - 0.013 14.8 0.0 0.033 13.5 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin AAA_28 PF13521.6 CBZ28858.1 - 0.013 15.7 0.0 0.049 13.9 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 CBZ28858.1 - 0.02 15.0 1.0 0.044 13.9 0.0 2.0 2 0 0 2 2 2 0 AAA domain Big_2 PF02368.18 CBZ28858.1 - 0.021 14.7 1.2 13 5.7 0.1 4.8 3 0 0 3 3 3 0 Bacterial Ig-like domain (group 2) AAA_22 PF13401.6 CBZ28858.1 - 0.072 13.4 0.0 0.19 12.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 CBZ28858.1 - 0.094 13.1 2.6 0.33 11.3 0.0 2.7 2 0 0 2 2 2 0 AAA ATPase domain KTI12 PF08433.10 CBZ28858.1 - 0.2 11.0 0.0 0.38 10.2 0.0 1.3 1 0 0 1 1 1 0 Chromatin associated protein KTI12 PapD_N PF00345.20 CBZ28858.1 - 0.2 11.5 0.4 6.8 6.6 0.0 3.9 5 0 0 5 5 3 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain Porphyrn_cat_1 PF18206.1 CBZ28858.1 - 0.21 12.2 0.1 1.3 9.7 0.1 2.5 1 0 0 1 1 1 0 Porphyranase catalytic subdomain 1 DUF3449 PF11931.8 CBZ28859.1 - 1.8e-38 132.2 0.2 1.8e-38 132.2 0.2 2.2 2 1 0 2 2 2 1 Domain of unknown function (DUF3449) SF3A3 PF16837.5 CBZ28859.1 - 5.6e-10 39.6 0.0 2.2e-09 37.7 0.0 2.0 2 0 0 2 2 2 1 Pre-mRNA-splicing factor SF3A3, of SF3a complex, Prp9 zf-RING_7 PF02591.15 CBZ28859.1 - 0.16 12.2 0.0 22 5.4 0.0 2.9 2 0 0 2 2 2 0 C4-type zinc ribbon domain FYVE PF01363.21 CBZ28861.1 - 2.5e-11 43.5 8.3 3.2e-11 43.2 5.3 2.5 2 0 0 2 2 2 1 FYVE zinc finger PI3_PI4_kinase PF00454.27 CBZ28861.1 - 9.7e-10 38.7 0.3 1e-07 32.0 0.1 2.4 2 0 0 2 2 2 2 Phosphatidylinositol 3- and 4-kinase OrfB_Zn_ribbon PF07282.11 CBZ28861.1 - 0.24 11.4 2.7 0.75 9.8 2.7 1.8 1 0 0 1 1 1 0 Putative transposase DNA-binding domain zf-ribbon_3 PF13248.6 CBZ28861.1 - 0.24 10.9 2.1 2.8 7.5 2.1 2.6 1 1 0 1 1 1 0 zinc-ribbon domain IBR PF01485.21 CBZ28861.1 - 7.9 6.8 10.7 0.33 11.2 2.6 2.6 2 0 0 2 2 2 0 IBR domain, a half RING-finger domain C_tripleX PF02363.19 CBZ28862.1 - 0.16 12.3 0.7 0.39 11.1 0.7 1.7 1 0 0 1 1 1 0 Cysteine rich repeat MCR PF18509.1 CBZ28864.1 - 0.059 13.0 1.1 0.39 10.3 0.1 2.3 2 0 0 2 2 2 0 Magnetochrome domain AAA_18 PF13238.6 CBZ28865.1 - 2.6e-28 99.2 0.3 3.9e-28 98.6 0.0 1.4 2 0 0 2 2 1 1 AAA domain AAA_17 PF13207.6 CBZ28865.1 - 3.9e-08 33.8 1.6 5.8e-08 33.2 0.2 2.0 2 1 0 2 2 1 1 AAA domain AAA_33 PF13671.6 CBZ28865.1 - 5.8e-07 29.8 0.3 0.00014 22.1 0.1 2.4 2 1 0 2 2 1 1 AAA domain AAA PF00004.29 CBZ28865.1 - 1.4e-05 25.5 0.1 1.9e-05 25.1 0.1 1.7 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.6 CBZ28865.1 - 1.5e-05 25.3 1.1 0.00032 21.0 0.0 2.3 2 1 0 2 2 2 1 AAA domain AAA_22 PF13401.6 CBZ28865.1 - 0.00021 21.6 0.0 0.00051 20.3 0.0 1.5 2 0 0 2 2 1 1 AAA domain RuvB_N PF05496.12 CBZ28865.1 - 0.00026 20.7 0.0 0.00047 19.9 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain dNK PF01712.19 CBZ28865.1 - 0.00088 19.2 0.9 0.4 10.5 0.1 2.3 1 1 0 2 2 2 2 Deoxynucleoside kinase ADK PF00406.22 CBZ28865.1 - 0.0015 18.7 0.3 0.26 11.4 0.0 2.2 1 1 1 2 2 2 1 Adenylate kinase NTPase_1 PF03266.15 CBZ28865.1 - 0.0022 17.9 0.3 0.011 15.6 0.0 2.3 2 1 1 3 3 3 1 NTPase AAA_16 PF13191.6 CBZ28865.1 - 0.003 18.0 0.1 0.004 17.6 0.1 1.6 1 1 0 1 1 1 1 AAA ATPase domain DUF2075 PF09848.9 CBZ28865.1 - 0.0038 16.5 0.0 0.0059 15.9 0.0 1.4 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) Parvo_NS1 PF01057.17 CBZ28865.1 - 0.0062 15.7 0.0 0.012 14.7 0.0 1.5 1 0 0 1 1 1 1 Parvovirus non-structural protein NS1 AAA_5 PF07728.14 CBZ28865.1 - 0.0076 16.2 0.0 0.024 14.6 0.0 1.8 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) RNA_helicase PF00910.22 CBZ28865.1 - 0.0098 16.3 0.0 0.018 15.4 0.0 1.5 1 0 0 1 1 1 1 RNA helicase Zeta_toxin PF06414.12 CBZ28865.1 - 0.01 15.2 0.2 0.02 14.2 0.0 1.7 2 1 1 3 3 3 0 Zeta toxin TIP49 PF06068.13 CBZ28865.1 - 0.011 14.9 0.0 0.02 14.1 0.0 1.4 1 0 0 1 1 1 0 TIP49 P-loop domain AAA_24 PF13479.6 CBZ28865.1 - 0.011 15.4 1.0 0.037 13.7 0.2 2.0 1 1 0 2 2 2 0 AAA domain ATPase_2 PF01637.18 CBZ28865.1 - 0.012 15.5 0.1 0.021 14.8 0.1 1.5 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_19 PF13245.6 CBZ28865.1 - 0.013 15.9 0.8 0.023 15.0 0.1 1.8 2 1 0 2 2 2 0 AAA domain ABC_tran PF00005.27 CBZ28865.1 - 0.013 16.0 1.3 0.077 13.5 1.3 2.0 1 1 0 1 1 1 0 ABC transporter SKI PF01202.22 CBZ28865.1 - 0.015 15.5 4.1 0.14 12.2 4.1 2.2 1 1 0 1 1 1 0 Shikimate kinase Mg_chelatase PF01078.21 CBZ28865.1 - 0.016 14.6 0.1 0.05 13.0 0.0 1.8 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI CoaE PF01121.20 CBZ28865.1 - 0.017 14.8 0.5 0.58 9.8 0.1 2.2 2 0 0 2 2 2 0 Dephospho-CoA kinase ATPase PF06745.13 CBZ28865.1 - 0.017 14.5 1.6 0.02 14.2 0.1 1.8 2 0 0 2 2 2 0 KaiC Sigma54_activat PF00158.26 CBZ28865.1 - 0.018 14.7 0.0 0.04 13.6 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain Torsin PF06309.11 CBZ28865.1 - 0.028 14.5 0.0 0.05 13.7 0.0 1.4 1 0 0 1 1 1 0 Torsin KTI12 PF08433.10 CBZ28865.1 - 0.034 13.6 0.1 0.12 11.8 0.0 1.8 2 0 0 2 2 2 0 Chromatin associated protein KTI12 IstB_IS21 PF01695.17 CBZ28865.1 - 0.041 13.6 0.1 0.096 12.4 0.0 1.7 2 0 0 2 2 2 0 IstB-like ATP binding protein KAP_NTPase PF07693.14 CBZ28865.1 - 0.041 13.1 0.0 0.059 12.6 0.0 1.4 1 1 0 1 1 1 0 KAP family P-loop domain CPT PF07931.12 CBZ28865.1 - 0.045 13.6 2.6 0.63 9.9 0.0 2.8 2 1 1 3 3 3 0 Chloramphenicol phosphotransferase-like protein AAA_7 PF12775.7 CBZ28865.1 - 0.052 13.1 0.0 0.081 12.4 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region Thymidylate_kin PF02223.17 CBZ28865.1 - 0.052 13.2 1.0 7.5 6.2 0.1 2.3 2 1 0 2 2 2 0 Thymidylate kinase Sars6 PF12133.8 CBZ28865.1 - 0.085 12.8 0.0 0.2 11.6 0.0 1.6 1 0 0 1 1 1 0 Open reading frame 6 from SARS coronavirus AAA_29 PF13555.6 CBZ28865.1 - 0.099 12.4 0.0 0.18 11.6 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_3 PF07726.11 CBZ28865.1 - 0.12 12.3 0.0 0.25 11.2 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Viral_helicase1 PF01443.18 CBZ28865.1 - 0.18 11.5 0.9 7.9 6.1 0.1 2.1 1 1 1 2 2 2 0 Viral (Superfamily 1) RNA helicase SPT2 PF08243.11 CBZ28865.1 - 5.5 7.6 9.4 2.5 8.6 1.9 2.7 2 1 1 3 3 3 0 SPT2 chromatin protein CoA_trans PF01144.23 CBZ28868.1 - 6.7e-100 332.9 0.0 3.4e-60 203.1 0.0 2.0 2 0 0 2 2 2 2 Coenzyme A transferase AcetylCoA_hyd_C PF13336.6 CBZ28868.1 - 0.0089 16.0 0.0 0.016 15.2 0.0 1.3 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase C-terminal domain CoA_trans PF01144.23 CBZ28869.1 - 4.6e-95 317.1 0.1 1.1e-59 201.4 0.0 2.0 2 0 0 2 2 2 2 Coenzyme A transferase AcetylCoA_hyd_C PF13336.6 CBZ28869.1 - 2.6e-05 24.2 0.0 4.7e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase C-terminal domain PseudoU_synth_2 PF00849.22 CBZ28871.1 - 5.3e-23 81.9 0.6 2.6e-13 50.4 0.1 3.0 3 0 0 3 3 3 2 RNA pseudouridylate synthase S4 PF01479.25 CBZ28871.1 - 0.019 14.6 0.0 0.043 13.5 0.0 1.6 1 0 0 1 1 1 0 S4 domain TPR_MLP1_2 PF07926.12 CBZ28872.1 - 0.00074 19.6 19.6 0.079 13.0 0.9 3.7 2 1 0 3 3 3 3 TPR/MLP1/MLP2-like protein Rbsn PF11464.8 CBZ28872.1 - 0.0041 16.8 1.6 0.012 15.3 0.0 2.7 3 0 0 3 3 3 1 Rabenosyn Rab binding domain DUF1154 PF06631.11 CBZ28872.1 - 0.18 11.8 3.5 0.33 11.0 1.9 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1154) Laminin_II PF06009.12 CBZ28872.1 - 0.23 11.5 9.2 13 5.7 0.0 4.0 4 0 0 4 4 4 0 Laminin Domain II OmpH PF03938.14 CBZ28872.1 - 0.34 11.2 16.7 20 5.5 12.0 3.2 2 1 1 3 3 3 0 Outer membrane protein (OmpH-like) DUF1664 PF07889.12 CBZ28872.1 - 0.35 10.9 10.6 22 5.1 0.1 4.1 2 1 2 5 5 5 0 Protein of unknown function (DUF1664) BILBO1_N PF18281.1 CBZ28873.1 - 4.1e-21 75.2 0.0 9e-21 74.1 0.0 1.6 1 0 0 1 1 1 1 BILBO1 N-terminal domain zf-C2H2_2 PF12756.7 CBZ28874.1 - 3.7e-20 72.1 9.4 6.7e-14 52.0 3.5 2.3 2 0 0 2 2 2 2 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.6 CBZ28874.1 - 0.00043 20.9 10.2 0.9 10.6 1.4 4.3 3 0 0 3 3 3 2 C2H2-type zinc finger zf-Di19 PF05605.12 CBZ28874.1 - 0.0005 20.3 15.4 0.014 15.7 0.4 4.1 3 1 0 4 4 4 2 Drought induced 19 protein (Di19), zinc-binding Rubredoxin PF00301.20 CBZ28874.1 - 0.13 12.3 0.2 0.13 12.3 0.2 2.7 4 0 0 4 4 4 0 Rubredoxin zf-C2H2_12 PF18658.1 CBZ28874.1 - 0.41 10.3 0.0 0.41 10.3 0.0 2.8 3 0 0 3 3 3 0 Zinc-finger C2H2-type zf-BED PF02892.15 CBZ28874.1 - 0.46 10.6 0.0 0.46 10.6 0.0 4.2 3 1 0 3 3 3 0 BED zinc finger zf-C2H2 PF00096.26 CBZ28874.1 - 2.1 9.0 18.5 2.1 9.0 1.2 4.6 4 2 0 4 4 4 0 Zinc finger, C2H2 type zf-H2C2_5 PF13909.6 CBZ28874.1 - 7.9 6.3 7.0 98 2.8 3.6 3.6 2 1 0 2 2 2 0 C2H2-type zinc-finger domain TetR_C_6 PF13977.6 CBZ28876.1 - 0.13 12.5 4.9 0.057 13.6 0.9 2.5 2 0 0 2 2 2 0 BetI-type transcriptional repressor, C-terminal PC_rep PF01851.22 CBZ28876.1 - 0.18 12.3 9.7 1.4e+02 3.2 0.0 6.5 7 0 0 7 7 7 0 Proteasome/cyclosome repeat IFT20 PF14931.6 CBZ28877.1 - 7.4e-35 119.7 7.4 8.3e-35 119.5 7.4 1.0 1 0 0 1 1 1 1 Intraflagellar transport complex B, subunit 20 VQ PF05678.14 CBZ28877.1 - 0.013 14.9 1.9 0.72 9.4 0.1 2.9 3 0 0 3 3 3 0 VQ motif Haem_bd PF14376.6 CBZ28877.1 - 0.038 13.9 0.2 0.049 13.6 0.2 1.2 1 0 0 1 1 1 0 Haem-binding domain DUF459 PF04311.13 CBZ28877.1 - 0.039 12.9 0.0 0.05 12.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF459) ISG65-75 PF11727.8 CBZ28877.1 - 0.25 10.5 3.1 0.3 10.3 3.1 1.0 1 0 0 1 1 1 0 Invariant surface glycoprotein Mannosyl_trans PF05007.13 CBZ28880.1 - 2.2e-82 276.8 9.5 3.1e-82 276.3 9.5 1.2 1 0 0 1 1 1 1 Mannosyltransferase (PIG-M) GT87 PF09594.10 CBZ28880.1 - 4.8e-11 42.8 13.7 4.8e-11 42.8 13.7 2.5 1 1 0 2 2 2 1 Glycosyltransferase family 87 PIG-U PF06728.13 CBZ28880.1 - 6.2e-09 35.4 15.6 1.7e-08 34.0 15.3 1.8 1 1 0 1 1 1 1 GPI transamidase subunit PIG-U Peptidase_C2 PF00648.21 CBZ28881.1 - 8e-25 87.5 0.4 7.9e-12 44.8 0.0 3.9 4 0 0 4 4 4 3 Calpain family cysteine protease LRR_4 PF12799.7 CBZ28881.1 - 0.028 14.9 4.1 0.75 10.3 1.6 2.6 1 1 0 2 2 2 0 Leucine Rich repeats (2 copies) Calpain_III PF01067.22 CBZ28881.1 - 0.037 14.3 0.0 7.2 6.9 0.0 3.1 3 0 0 3 3 3 0 Calpain large subunit, domain III LRR_1 PF00560.33 CBZ28881.1 - 0.05 14.1 4.6 27 5.8 0.1 3.9 3 0 0 3 3 3 0 Leucine Rich Repeat LRR_6 PF13516.6 CBZ28881.1 - 0.074 13.1 3.4 14 6.0 0.2 3.3 3 0 0 3 3 3 0 Leucine Rich repeat LRR_8 PF13855.6 CBZ28881.1 - 2.7 7.8 5.9 27 4.6 2.7 2.8 1 1 1 2 2 2 0 Leucine rich repeat Cytochrom_B561 PF03188.16 CBZ28882.1 - 9.3e-12 45.2 7.7 2.9e-11 43.7 7.7 1.7 1 1 0 1 1 1 1 Eukaryotic cytochrome b561 DUF2099 PF09872.9 CBZ28883.1 - 0.047 12.9 0.0 0.15 11.2 0.0 1.7 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2099) NFACT-R_1 PF05670.13 CBZ28885.1 - 1.1e-43 148.3 0.0 1.9e-43 147.6 0.0 1.4 1 0 0 1 1 1 1 NFACT protein RNA binding domain FTO_NTD PF12933.7 CBZ28885.1 - 0.084 12.1 2.2 0.084 12.1 1.1 1.5 2 0 0 2 2 2 0 FTO catalytic domain AAA_11 PF13086.6 CBZ28885.1 - 0.34 10.7 4.6 0.42 10.3 4.6 1.1 1 0 0 1 1 1 0 AAA domain DUF3987 PF13148.6 CBZ28885.1 - 0.97 8.4 6.9 1.2 8.1 6.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) AAA_16 PF13191.6 CBZ28886.1 - 0.0055 17.1 0.1 0.014 15.8 0.1 1.8 1 1 0 1 1 1 1 AAA ATPase domain NACHT PF05729.12 CBZ28886.1 - 0.011 15.7 0.0 0.027 14.4 0.0 1.6 1 0 0 1 1 1 0 NACHT domain AAA_18 PF13238.6 CBZ28886.1 - 0.024 15.2 0.0 0.063 13.8 0.0 1.8 1 1 0 1 1 1 0 AAA domain AAA_22 PF13401.6 CBZ28886.1 - 0.027 14.7 0.1 0.11 12.8 0.0 2.1 2 1 0 2 2 2 0 AAA domain AAA_30 PF13604.6 CBZ28886.1 - 0.037 13.7 0.2 0.11 12.3 0.2 1.8 1 1 0 1 1 1 0 AAA domain CbiA PF01656.23 CBZ28886.1 - 0.066 13.3 0.1 0.13 12.3 0.1 1.4 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain DUF87 PF01935.17 CBZ28886.1 - 0.1 12.7 0.0 0.2 11.7 0.0 1.5 1 0 0 1 1 1 0 Helicase HerA, central domain AAA_19 PF13245.6 CBZ28886.1 - 0.17 12.2 0.8 0.64 10.3 0.0 2.3 3 0 0 3 3 3 0 AAA domain Fe-ADH PF00465.19 CBZ28887.1 - 2e-115 385.5 0.8 2.2e-115 385.3 0.8 1.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.6 CBZ28887.1 - 8e-19 68.3 0.1 2.1e-11 44.0 0.0 2.3 2 0 0 2 2 2 2 Iron-containing alcohol dehydrogenase DUF1664 PF07889.12 CBZ28888.1 - 8.8e-05 22.5 0.6 0.00024 21.2 0.6 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF1664) DUF883 PF05957.13 CBZ28888.1 - 0.0077 16.8 0.9 0.025 15.2 0.9 1.9 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF883) Apolipoprotein PF01442.18 CBZ28888.1 - 0.0091 15.9 2.4 0.024 14.5 2.4 1.7 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain Exonuc_VII_L PF02601.15 CBZ28888.1 - 0.03 13.9 0.1 0.03 13.9 0.1 1.8 2 0 0 2 2 2 0 Exonuclease VII, large subunit Baculo_PEP_C PF04513.12 CBZ28888.1 - 0.055 13.5 0.6 0.12 12.4 0.6 1.5 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus FTA4 PF13093.6 CBZ28888.1 - 0.059 13.3 0.2 0.13 12.2 0.1 1.5 2 0 0 2 2 2 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 PMEI PF04043.15 CBZ28888.1 - 0.071 13.5 2.1 5.1 7.4 0.4 2.7 2 0 0 2 2 2 0 Plant invertase/pectin methylesterase inhibitor FlgN PF05130.12 CBZ28888.1 - 0.1 13.1 4.8 0.12 12.9 3.2 1.9 2 0 0 2 2 2 0 FlgN protein HisKA_3 PF07730.13 CBZ28888.1 - 0.1 13.1 1.8 0.46 11.1 1.8 2.2 1 0 0 1 1 1 0 Histidine kinase DUF4164 PF13747.6 CBZ28888.1 - 0.12 12.7 1.4 0.34 11.2 1.4 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4164) OmpH PF03938.14 CBZ28888.1 - 0.12 12.7 2.4 0.26 11.6 2.4 1.5 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Salp15 PF12115.8 CBZ28888.1 - 0.15 12.5 0.1 0.31 11.5 0.1 1.5 1 0 0 1 1 1 0 Salivary protein of 15kDa inhibits CD4+ T cell activation Fzo_mitofusin PF04799.13 CBZ28888.1 - 0.16 11.6 1.9 0.35 10.4 1.9 1.5 1 0 0 1 1 1 0 fzo-like conserved region Flagellin_N PF00669.20 CBZ28888.1 - 3.5 7.7 9.1 0.17 12.0 2.9 2.0 2 0 0 2 2 2 0 Bacterial flagellin N-terminal helical region RsfS PF02410.15 CBZ28890.1 - 2.3e-15 56.8 0.7 3.8e-15 56.1 0.7 1.3 1 0 0 1 1 1 1 Ribosomal silencing factor during starvation Pkinase PF00069.25 CBZ28891.1 - 2.6e-51 174.5 0.0 2.8e-37 128.5 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ28891.1 - 5.9e-34 117.5 0.0 1.1e-26 93.7 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Beta_helix PF13229.6 CBZ28891.1 - 4e-29 101.5 8.3 3e-14 53.1 0.1 2.5 1 1 1 2 2 2 2 Right handed beta helix region NosD PF05048.13 CBZ28891.1 - 5e-24 84.9 0.6 3.5e-14 52.6 0.8 2.6 1 1 1 2 2 2 2 Periplasmic copper-binding protein (NosD) Kinase-like PF14531.6 CBZ28891.1 - 0.0018 17.7 0.0 0.0036 16.6 0.0 1.5 1 0 0 1 1 1 1 Kinase-like DUF1565 PF07602.11 CBZ28891.1 - 0.0021 17.4 6.7 0.072 12.4 4.6 2.6 1 1 1 2 2 2 2 Protein of unknown function (DUF1565) APH PF01636.23 CBZ28891.1 - 0.052 13.5 0.1 0.61 10.0 0.0 2.6 3 1 0 3 3 3 0 Phosphotransferase enzyme family zf-B_box PF00643.24 CBZ28891.1 - 0.1 12.8 11.2 0.31 11.2 11.2 1.8 1 0 0 1 1 1 0 B-box zinc finger CEBP_ZZ PF16366.5 CBZ28891.1 - 0.89 9.8 10.4 2.8 8.3 10.4 1.8 1 0 0 1 1 1 0 Cytoplasmic polyadenylation element-binding protein ZZ domain IBR PF01485.21 CBZ28891.1 - 2 8.7 10.6 9.5 6.5 10.7 2.2 1 1 0 1 1 1 0 IBR domain, a half RING-finger domain Patatin PF01734.22 CBZ28892.1 - 2.5e-22 80.1 0.8 5.5e-22 78.9 0.0 2.0 2 0 0 2 2 2 1 Patatin-like phospholipase DUF3336 PF11815.8 CBZ28892.1 - 0.00013 21.6 0.0 0.00025 20.8 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3336) WD40 PF00400.32 CBZ28893.1 - 3e-08 34.2 7.4 0.33 11.9 0.0 7.7 8 0 0 8 8 8 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBZ28893.1 - 0.00055 20.2 0.1 1 9.7 0.0 4.5 4 1 1 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain IBR PF01485.21 CBZ28895.1 - 3.5e-15 56.0 27.2 4.1e-09 36.5 13.9 4.5 3 1 1 4 4 4 2 IBR domain, a half RING-finger domain zf-RING_UBOX PF13445.6 CBZ28895.1 - 0.011 15.7 4.7 0.011 15.7 4.7 3.1 3 0 0 3 3 3 0 RING-type zinc-finger zf-RING_5 PF14634.6 CBZ28895.1 - 0.015 15.2 12.5 0.015 15.2 12.5 4.3 3 1 1 4 4 4 0 zinc-RING finger domain zf-C3HC4 PF00097.25 CBZ28895.1 - 0.043 13.7 37.7 0.067 13.1 10.8 3.7 3 1 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CBZ28895.1 - 0.12 12.7 42.8 0.071 13.5 12.5 4.1 3 1 0 3 3 3 0 Ring finger domain RRM_1 PF00076.22 CBZ28896.1 - 6.9e-25 86.7 0.0 2.1e-14 53.1 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 CBZ28896.1 - 0.023 14.7 0.0 8.1 6.6 0.0 2.3 2 0 0 2 2 2 0 RNA binding motif RRM_Rrp7 PF17799.1 CBZ28896.1 - 0.052 13.3 0.0 0.54 10.0 0.0 2.2 1 1 1 2 2 2 0 Rrp7 RRM-like N-terminal domain SMN PF06003.12 CBZ28896.1 - 0.058 12.6 1.3 0.097 11.9 1.3 1.4 1 0 0 1 1 1 0 Survival motor neuron protein (SMN) PRIMA1 PF16101.5 CBZ28896.1 - 5.2 7.1 9.9 1.1 9.3 5.8 1.9 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 RRM_1 PF00076.22 CBZ28897.1 - 1.4e-23 82.5 2.7 4.3e-14 52.1 0.0 2.7 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_Rrp7 PF17799.1 CBZ28897.1 - 0.012 15.4 0.4 0.17 11.6 0.1 2.3 2 0 0 2 2 2 0 Rrp7 RRM-like N-terminal domain RRM_7 PF16367.5 CBZ28897.1 - 0.026 14.6 0.0 0.71 10.0 0.0 2.7 2 1 0 2 2 2 0 RNA recognition motif zf-CCCH PF00642.24 CBZ28898.1 - 2.8e-08 33.5 0.4 3.9e-08 33.0 0.4 1.2 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 CBZ28898.1 - 7.9e-07 28.7 0.8 1.1e-06 28.3 0.8 1.2 1 0 0 1 1 1 1 CCCH-type zinc finger zf_CCCH_4 PF18345.1 CBZ28898.1 - 7.1e-05 22.7 0.6 0.00021 21.2 0.6 1.8 1 1 0 1 1 1 1 Zinc finger domain zf-CCCH_2 PF14608.6 CBZ28898.1 - 0.0009 19.6 0.8 0.0014 19.0 0.8 1.3 1 0 0 1 1 1 1 RNA-binding, Nab2-type zinc finger zf-CCCH_3 PF15663.5 CBZ28898.1 - 0.11 12.8 0.1 0.2 11.9 0.1 1.4 1 0 0 1 1 1 0 Zinc-finger containing family Torus PF16131.5 CBZ28898.1 - 0.18 12.5 0.0 0.27 12.0 0.0 1.3 1 0 0 1 1 1 0 Torus domain GYF_2 PF14237.6 CBZ28899.1 - 1.7e-17 62.9 0.4 1.7e-17 62.9 0.4 1.9 2 0 0 2 2 2 1 GYF domain 2 DnaJ PF00226.31 CBZ28899.1 - 4.3e-15 55.6 0.3 1e-14 54.4 0.3 1.6 1 0 0 1 1 1 1 DnaJ domain CDC14 PF08045.11 CBZ28899.1 - 0.072 12.2 0.9 0.17 11.0 0.9 1.5 1 0 0 1 1 1 0 Cell division control protein 14, SIN component DUF155 PF02582.14 CBZ28900.1 - 2.3e-19 70.2 0.0 5.2e-19 69.0 0.0 1.6 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 APH PF01636.23 CBZ28901.1 - 0.083 12.8 0.0 0.12 12.3 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family Mito_carr PF00153.27 CBZ28902.1 - 5.1e-08 32.7 13.7 0.18 11.8 0.5 5.4 6 1 0 6 6 6 4 Mitochondrial carrier protein CytB6-F_Fe-S PF08802.10 CBZ28902.1 - 1.9 8.6 5.5 0.22 11.6 0.5 2.0 2 0 0 2 2 2 0 Cytochrome B6-F complex Fe-S subunit zf-C2H2_2 PF12756.7 CBZ28903.1 - 1.3e-23 83.3 10.9 1.4e-18 67.1 1.5 3.2 2 1 0 2 2 2 2 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.8 CBZ28903.1 - 1.1e-10 41.5 5.8 3.3e-07 30.4 0.7 4.0 3 1 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 CBZ28903.1 - 1.1e-06 28.4 8.6 0.0046 16.9 1.6 3.7 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_4 PF13894.6 CBZ28903.1 - 3.7e-06 27.3 10.5 0.0034 18.1 1.3 4.3 4 0 0 4 4 4 2 C2H2-type zinc finger zf-met PF12874.7 CBZ28903.1 - 0.00019 21.7 13.1 0.007 16.7 2.5 3.8 3 1 0 3 3 3 2 Zinc-finger of C2H2 type zf-C2H2_12 PF18658.1 CBZ28903.1 - 0.00088 18.8 9.8 0.017 14.6 0.1 3.7 2 1 1 3 3 3 1 Zinc-finger C2H2-type zf-C2H2 PF00096.26 CBZ28903.1 - 0.0038 17.6 16.0 0.05 14.1 2.7 4.0 4 0 0 4 4 4 2 Zinc finger, C2H2 type zf_Hakai PF18408.1 CBZ28903.1 - 0.045 13.5 0.7 0.14 11.9 0.7 1.9 1 0 0 1 1 1 0 C2H2 Hakai zinc finger domain zf-LYAR PF08790.11 CBZ28903.1 - 1.2 9.1 5.3 0.25 11.3 1.2 2.1 2 0 0 2 2 2 0 LYAR-type C2HC zinc finger FRG1 PF06229.12 CBZ28903.1 - 1.4 8.6 4.9 0.55 9.9 1.9 1.7 2 0 0 2 2 2 0 FRG1-like domain zf_C2H2_ZHX PF18387.1 CBZ28903.1 - 3.4 7.4 14.4 7.2 6.3 0.1 4.5 4 0 0 4 4 4 0 Zinc-fingers and homeoboxes C2H2 finger domain PhoLip_ATPase_C PF16212.5 CBZ28904.1 - 3e-39 135.3 14.6 7e-39 134.1 14.6 1.6 1 0 0 1 1 1 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 CBZ28904.1 - 8.9e-19 66.9 2.9 2.2e-18 65.7 2.9 1.6 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Hydrolase PF00702.26 CBZ28904.1 - 5.6e-11 43.1 0.1 0.0001 22.7 0.3 3.2 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 CBZ28904.1 - 1.9e-06 27.9 0.0 5.4e-06 26.4 0.0 1.8 2 0 0 2 2 2 1 Cation transport ATPase (P-type) E1-E2_ATPase PF00122.20 CBZ28904.1 - 8.6e-06 25.4 0.0 6.2e-05 22.6 0.0 2.3 1 1 0 1 1 1 1 E1-E2 ATPase Hydrolase_3 PF08282.12 CBZ28904.1 - 0.022 14.5 0.1 0.04 13.6 0.1 1.3 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase KRTAP7 PF15034.6 CBZ28904.1 - 0.19 12.7 1.1 0.4 11.7 0.0 2.1 2 0 0 2 2 2 0 KRTAP type 7 family LRR_4 PF12799.7 CBZ28905.1 - 7.2e-18 64.4 14.5 8.9e-06 26.0 0.4 6.9 6 2 1 7 7 7 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CBZ28905.1 - 2.2e-15 56.1 13.0 1.8e-06 27.6 0.0 6.3 6 0 0 6 6 6 3 Leucine rich repeat LRR_9 PF14580.6 CBZ28905.1 - 7.9e-05 22.2 1.6 0.0028 17.2 0.1 3.3 2 1 2 4 4 4 1 Leucine-rich repeat LRR_6 PF13516.6 CBZ28905.1 - 0.00015 21.5 11.9 11 6.4 0.2 7.7 8 0 0 8 8 8 2 Leucine Rich repeat LRR_1 PF00560.33 CBZ28905.1 - 0.098 13.3 14.4 28 5.8 0.1 6.5 7 1 0 7 7 7 0 Leucine Rich Repeat TTL PF03133.15 CBZ28906.1 - 2.2e-50 171.5 0.0 1.3e-30 106.6 0.0 3.1 2 1 0 2 2 2 2 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 CBZ28906.1 - 2.8e-07 30.1 0.0 0.0056 16.0 0.0 2.3 2 0 0 2 2 2 2 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 CBZ28906.1 - 2.2e-06 27.1 0.0 0.049 12.9 0.0 2.2 2 0 0 2 2 2 2 Sugar-transfer associated ATP-grasp Dala_Dala_lig_C PF07478.13 CBZ28906.1 - 0.11 12.0 0.1 0.22 11.1 0.1 1.4 1 0 0 1 1 1 0 D-ala D-ala ligase C-terminus DEAD PF00270.29 CBZ28907.1 - 2.9e-14 53.2 0.0 6.8e-14 52.0 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CBZ28907.1 - 8.2e-12 45.5 0.0 1.8e-11 44.3 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Lzipper-MIP1 PF14389.6 CBZ28907.1 - 0.11 12.8 0.1 0.38 11.1 0.1 1.9 1 0 0 1 1 1 0 Leucine-zipper of ternary complex factor MIP1 MRF_C1 PF13887.6 CBZ28907.1 - 0.19 10.9 0.0 0.96 8.7 0.0 2.3 2 0 0 2 2 2 0 Myelin gene regulatory factor -C-terminal domain 1 RF3_C PF16658.5 CBZ28908.1 - 0.033 14.0 0.3 0.089 12.6 0.2 1.7 1 1 0 1 1 1 0 Class II release factor RF3, C-terminal domain DOR PF14839.6 CBZ28908.1 - 0.039 13.9 3.4 0.16 11.9 3.4 2.0 1 0 0 1 1 1 0 DOR family Not3 PF04065.15 CBZ28908.1 - 0.07 12.5 4.2 0.11 11.9 4.2 1.2 1 0 0 1 1 1 0 Not1 N-terminal domain, CCR4-Not complex component PUA_3 PF17785.1 CBZ28909.1 - 0.025 14.4 0.0 0.058 13.2 0.0 1.6 1 0 0 1 1 1 0 PUA-like domain SET PF00856.28 CBZ28910.1 - 1.7e-10 41.6 0.0 3.2e-10 40.6 0.0 1.5 1 1 0 1 1 1 1 SET domain zf-C2H2_4 PF13894.6 CBZ28912.1 - 0.016 16.0 0.1 0.051 14.4 0.1 2.0 1 0 0 1 1 1 0 C2H2-type zinc finger zf-C2H2 PF00096.26 CBZ28912.1 - 0.033 14.6 0.6 0.082 13.4 0.6 1.7 1 0 0 1 1 1 0 Zinc finger, C2H2 type TPR_MLP1_2 PF07926.12 CBZ28912.1 - 0.055 13.5 7.3 0.091 12.8 5.0 2.5 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein Pyridoxal_deC PF00282.19 CBZ28913.1 - 2.7e-18 65.8 0.0 4.4e-18 65.1 0.0 1.3 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.19 CBZ28913.1 - 1e-10 41.1 0.0 3.4e-10 39.4 0.0 1.8 1 1 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 CBZ28913.1 - 0.011 15.0 0.0 0.018 14.3 0.0 1.2 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family zf-C3HC4 PF00097.25 CBZ28914.1 - 1e-08 34.9 7.4 1e-08 34.9 7.4 3.3 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 CBZ28914.1 - 1.1e-08 35.1 7.6 1.1e-08 35.1 7.6 3.7 3 1 1 4 4 4 1 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.6 CBZ28914.1 - 1.9e-07 30.8 8.2 1.9e-07 30.8 8.2 3.6 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CBZ28914.1 - 3.7e-07 30.0 6.8 3.7e-07 30.0 6.8 3.1 3 0 0 3 3 3 1 RING-type zinc-finger zf-B_box PF00643.24 CBZ28914.1 - 1.1e-06 28.6 6.4 1.1e-06 28.6 6.4 4.3 4 0 0 4 4 4 2 B-box zinc finger zf-RING_2 PF13639.6 CBZ28914.1 - 1.5e-05 25.2 8.1 1.5e-05 25.2 8.1 3.5 2 1 1 3 3 3 1 Ring finger domain zf-RING_5 PF14634.6 CBZ28914.1 - 7.4e-05 22.6 8.5 7.4e-05 22.6 8.5 3.6 3 0 0 3 3 3 1 zinc-RING finger domain Spc7 PF08317.11 CBZ28914.1 - 0.018 14.0 1.0 0.026 13.4 1.0 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein Flg_hook PF02120.16 CBZ28914.1 - 0.1 12.5 0.4 0.28 11.1 0.4 1.7 1 0 0 1 1 1 0 Flagellar hook-length control protein FliK Arf PF00025.21 CBZ28915.1 - 1.3e-49 168.0 0.0 1.5e-49 167.8 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 CBZ28915.1 - 1.3e-17 63.8 0.0 1.7e-17 63.4 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.22 CBZ28915.1 - 2.3e-11 43.6 0.0 2.8e-11 43.3 0.0 1.1 1 0 0 1 1 1 1 Ras family G-alpha PF00503.20 CBZ28915.1 - 5.2e-11 42.3 0.0 1.1e-06 28.1 0.0 2.2 1 1 1 2 2 2 2 G-protein alpha subunit MMR_HSR1 PF01926.23 CBZ28915.1 - 7.5e-11 42.1 0.0 9.9e-11 41.7 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Roc PF08477.13 CBZ28915.1 - 5.8e-10 39.4 0.0 8e-10 39.0 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Gtr1_RagA PF04670.12 CBZ28915.1 - 3.3e-06 26.6 0.0 5.8e-06 25.8 0.0 1.4 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region FeoB_N PF02421.18 CBZ28915.1 - 0.00013 21.6 0.0 0.00021 20.9 0.0 1.5 1 1 0 1 1 1 1 Ferrous iron transport protein B GTP_EFTU PF00009.27 CBZ28915.1 - 0.004 16.7 0.1 0.11 12.0 0.0 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain TniB PF05621.11 CBZ28915.1 - 0.011 15.2 0.0 0.016 14.7 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein MeaB PF03308.16 CBZ28915.1 - 0.013 14.5 0.0 0.1 11.6 0.0 1.9 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_18 PF13238.6 CBZ28915.1 - 0.045 14.3 0.0 0.068 13.7 0.0 1.6 1 1 0 1 1 1 0 AAA domain NOG1 PF06858.14 CBZ28915.1 - 0.051 13.3 0.2 0.11 12.3 0.2 1.6 1 1 0 1 1 1 0 Nucleolar GTP-binding protein 1 (NOG1) CdhD PF03599.16 CBZ28915.1 - 0.066 11.9 0.0 0.09 11.5 0.0 1.2 1 0 0 1 1 1 0 CO dehydrogenase/acetyl-CoA synthase delta subunit cobW PF02492.19 CBZ28915.1 - 0.13 11.9 0.1 5.4 6.6 0.0 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain DLIC PF05783.11 CBZ28915.1 - 0.13 11.0 0.0 0.15 10.8 0.0 1.3 1 1 0 1 1 1 0 Dynein light intermediate chain (DLIC) MMR_HSR1_Xtn PF16897.5 CBZ28915.1 - 0.16 12.0 0.0 0.23 11.5 0.0 1.3 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain Rnk_N PF14760.6 CBZ28916.1 - 0.27 11.7 0.4 0.27 11.7 0.4 3.3 3 0 0 3 3 3 0 Rnk N-terminus HIP1_clath_bdg PF16515.5 CBZ28916.1 - 1.4 9.6 35.0 0.17 12.5 0.5 3.8 3 1 1 4 4 4 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Sulfatase_C PF14707.6 CBZ28916.1 - 4.4 8.1 7.0 26 5.6 1.8 3.1 3 0 0 3 3 3 0 C-terminal region of aryl-sulfatase THRAP3_BCLAF1 PF15440.6 CBZ28917.1 - 0.6 9.1 7.7 1.6 7.6 0.0 2.1 2 0 0 2 2 2 0 THRAP3/BCLAF1 family OpgC_C PF10129.9 CBZ28918.1 - 0.0049 15.8 1.9 0.0065 15.4 1.9 1.1 1 0 0 1 1 1 1 OpgC protein CLP1_P PF16575.5 CBZ28919.1 - 6.9e-36 123.8 0.0 1e-35 123.2 0.0 1.3 1 0 0 1 1 1 1 mRNA cleavage and polyadenylation factor CLP1 P-loop CLP1_N PF16573.5 CBZ28919.1 - 0.003 17.7 0.0 0.0056 16.9 0.0 1.4 1 0 0 1 1 1 1 N-terminal beta-sandwich domain of polyadenylation factor Clp1 PF06807.14 CBZ28919.1 - 0.013 15.9 0.0 0.033 14.6 0.0 1.7 1 0 0 1 1 1 0 Pre-mRNA cleavage complex II protein Clp1 PTH2 PF01981.16 CBZ28920.1 - 4.8e-19 68.8 0.1 6.9e-19 68.3 0.1 1.2 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase PTH2 TPR_2 PF07719.17 CBZ28922.1 - 0.007 16.4 0.0 2.8 8.3 0.0 2.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_9 PF13371.6 CBZ28922.1 - 0.013 15.6 0.1 0.076 13.2 0.3 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF2256 PF10013.9 CBZ28922.1 - 1.3 9.2 4.8 15 5.8 0.5 2.4 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2256) DnaJ PF00226.31 CBZ28923.1 - 1.7e-11 44.0 0.0 3.9e-11 42.9 0.0 1.6 1 0 0 1 1 1 1 DnaJ domain Plasmodium_Vir PF05795.11 CBZ28923.1 - 0.00021 20.9 1.1 0.00036 20.1 1.1 1.3 1 1 0 1 1 1 1 Plasmodium vivax Vir protein Dzip-like_N PF13815.6 CBZ28923.1 - 0.25 11.3 2.6 0.16 12.0 0.5 1.7 1 1 1 2 2 2 0 Iguana/Dzip1-like DAZ-interacting protein N-terminal HSP70 PF00012.20 CBZ28924.1 - 4.6e-245 814.4 4.2 5.3e-245 814.2 4.2 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 CBZ28924.1 - 8.8e-14 51.0 0.4 2e-12 46.6 0.1 2.5 2 1 0 2 2 2 1 MreB/Mbl protein StbA PF06406.11 CBZ28924.1 - 0.0016 17.7 0.7 0.53 9.5 0.0 3.0 3 1 1 4 4 4 2 StbA protein DeoC PF01791.9 CBZ28924.1 - 0.0027 17.4 0.4 2.8 7.5 0.0 3.0 3 0 0 3 3 3 2 DeoC/LacD family aldolase PqqD PF05402.12 CBZ28924.1 - 0.026 14.8 0.1 7.6 6.9 0.1 2.9 2 1 0 2 2 2 0 Coenzyme PQQ synthesis protein D (PqqD) DUF4404 PF14357.6 CBZ28924.1 - 0.59 10.8 2.5 1.1 10.0 0.8 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4404) DUF1690 PF07956.11 CBZ28924.1 - 8.5 6.8 8.2 3.4 8.1 5.2 1.8 2 0 0 2 2 2 0 Protein of Unknown function (DUF1690) HSP70 PF00012.20 CBZ28925.1 - 2.4e-148 495.0 0.6 2.7e-148 494.8 0.6 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 CBZ28925.1 - 1e-13 50.8 0.2 3.3e-12 45.9 0.0 2.2 2 0 0 2 2 2 2 MreB/Mbl protein StbA PF06406.11 CBZ28925.1 - 0.093 11.9 0.1 0.39 9.9 0.0 1.9 2 0 0 2 2 2 0 StbA protein HSP70 PF00012.20 CBZ28926.1 - 8.8e-259 859.7 8.6 8.8e-259 859.7 8.6 1.4 1 1 1 2 2 2 1 Hsp70 protein MreB_Mbl PF06723.13 CBZ28926.1 - 7.4e-14 51.3 0.6 1.6e-12 46.9 0.2 2.6 2 1 0 2 2 2 1 MreB/Mbl protein PqqD PF05402.12 CBZ28926.1 - 0.031 14.6 0.1 8 6.8 0.1 2.8 2 1 0 2 2 2 0 Coenzyme PQQ synthesis protein D (PqqD) AAA PF00004.29 CBZ28930.1 - 7.2e-47 159.1 0.0 1.7e-40 138.5 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 CBZ28930.1 - 2.8e-12 46.2 1.2 3.8e-09 36.2 0.3 2.8 2 0 0 2 2 2 2 AAA+ lid domain AAA_16 PF13191.6 CBZ28930.1 - 3.1e-09 37.4 1.1 0.013 15.9 0.8 4.3 2 2 0 3 3 3 2 AAA ATPase domain AAA_22 PF13401.6 CBZ28930.1 - 3.9e-07 30.4 0.0 0.01 16.1 0.0 3.1 2 1 1 3 3 3 2 AAA domain RuvB_N PF05496.12 CBZ28930.1 - 4.5e-05 23.2 0.0 0.0008 19.2 0.0 2.5 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 CBZ28930.1 - 0.0002 21.4 0.1 0.057 13.4 0.0 3.3 3 1 0 3 3 2 1 AAA domain (dynein-related subfamily) AAA_33 PF13671.6 CBZ28930.1 - 0.00025 21.2 0.1 0.58 10.3 0.0 2.9 3 0 0 3 3 2 2 AAA domain AAA_7 PF12775.7 CBZ28930.1 - 0.001 18.6 0.0 0.75 9.3 0.0 2.6 2 1 0 2 2 2 2 P-loop containing dynein motor region Vps4_C PF09336.10 CBZ28930.1 - 0.0011 18.9 0.1 0.005 16.8 0.0 2.1 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain NACHT PF05729.12 CBZ28930.1 - 0.0034 17.3 0.0 2.3 8.1 0.0 2.6 2 0 0 2 2 2 2 NACHT domain RNA_helicase PF00910.22 CBZ28930.1 - 0.0035 17.7 0.0 0.39 11.1 0.0 2.8 3 0 0 3 3 2 1 RNA helicase IstB_IS21 PF01695.17 CBZ28930.1 - 0.0042 16.8 0.1 0.4 10.4 0.0 2.5 2 0 0 2 2 2 1 IstB-like ATP binding protein TIP49 PF06068.13 CBZ28930.1 - 0.0047 16.2 0.0 0.0089 15.3 0.0 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain Mg_chelatase PF01078.21 CBZ28930.1 - 0.0061 16.0 0.0 0.076 12.4 0.0 2.2 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_2 PF07724.14 CBZ28930.1 - 0.015 15.5 0.0 0.047 13.8 0.0 1.8 2 0 0 2 2 1 0 AAA domain (Cdc48 subfamily) AAA_25 PF13481.6 CBZ28930.1 - 0.016 14.8 1.0 3.9 7.0 0.0 4.0 3 1 0 3 3 3 0 AAA domain ABC_tran PF00005.27 CBZ28930.1 - 0.038 14.5 0.0 2.5 8.6 0.0 2.3 2 0 0 2 2 2 0 ABC transporter Rad17 PF03215.15 CBZ28930.1 - 0.047 13.6 0.0 0.088 12.7 0.0 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain MCM PF00493.23 CBZ28930.1 - 0.054 12.6 0.0 2.1 7.4 0.0 2.6 3 0 0 3 3 3 0 MCM P-loop domain TniB PF05621.11 CBZ28930.1 - 0.13 11.6 0.0 2.4 7.6 0.0 2.5 2 0 0 2 2 2 0 Bacterial TniB protein Sigma54_activat PF00158.26 CBZ28930.1 - 0.15 11.7 0.0 18 5.0 0.0 2.8 2 0 0 2 2 2 0 Sigma-54 interaction domain HSP70 PF00012.20 CBZ28931.1 - 3.2e-259 861.2 8.7 3.7e-259 861.0 8.7 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 CBZ28931.1 - 2.6e-13 49.5 0.8 5.3e-12 45.2 0.3 2.6 2 1 0 2 2 2 1 MreB/Mbl protein PqqD PF05402.12 CBZ28931.1 - 0.067 13.5 0.1 7.8 6.9 0.1 2.8 2 1 0 2 2 2 0 Coenzyme PQQ synthesis protein D (PqqD) PIN_3 PF13470.6 CBZ28931.1 - 0.14 12.9 0.4 1.2 10.0 0.0 2.3 2 0 0 2 2 2 0 PIN domain DUF1690 PF07956.11 CBZ28931.1 - 1.1 9.7 10.7 0.29 11.6 7.1 1.9 2 0 0 2 2 2 0 Protein of Unknown function (DUF1690) DUF4404 PF14357.6 CBZ28931.1 - 1.7 9.4 5.4 0.94 10.2 1.0 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4404) TSNAXIP1_N PF15739.5 CBZ28932.1 - 8.7e-07 29.3 6.4 9.5e-07 29.2 1.1 3.0 1 1 1 2 2 2 1 Translin-associated factor X-interacting N-terminus AAA_13 PF13166.6 CBZ28932.1 - 0.29 9.7 6.1 0.45 9.1 6.1 1.2 1 0 0 1 1 1 0 AAA domain Band_3_cyto PF07565.13 CBZ28932.1 - 0.37 10.5 4.9 0.8 9.5 4.9 1.4 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Uso1_p115_C PF04871.13 CBZ28932.1 - 4.6 7.6 18.0 1.5 9.2 12.9 2.6 1 1 1 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region Cofilin_ADF PF00241.20 CBZ28933.1 - 3.9e-11 42.8 0.0 3.3e-08 33.4 0.0 2.4 2 0 0 2 2 2 2 Cofilin/tropomyosin-type actin-binding protein DUF4689 PF15755.5 CBZ28933.1 - 0.014 15.0 0.5 0.21 11.1 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4689) RecT PF03837.14 CBZ28933.1 - 0.095 12.2 0.0 0.2 11.1 0.0 1.5 1 0 0 1 1 1 0 RecT family Reticulon PF02453.17 CBZ28934.1 - 3.9e-25 88.6 8.2 4.8e-25 88.3 8.2 1.1 1 0 0 1 1 1 1 Reticulon DUF3292 PF11696.8 CBZ28934.1 - 0.016 13.6 0.5 0.027 12.9 0.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3292) PRT_C PF08372.10 CBZ28934.1 - 0.045 13.5 3.2 0.36 10.6 0.1 2.3 2 0 0 2 2 2 0 Plant phosphoribosyltransferase C-terminal MWFE PF15879.5 CBZ28934.1 - 0.078 13.2 0.0 0.24 11.6 0.0 1.9 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase MWFE subunit PrgI PF12666.7 CBZ28934.1 - 0.087 13.5 10.4 0.13 13.0 0.2 2.4 2 1 0 2 2 2 0 PrgI family protein Phage_holin_3_6 PF07332.11 CBZ28934.1 - 0.16 12.0 6.8 2.2 8.4 1.1 2.2 2 0 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III Pex24p PF06398.11 CBZ28934.1 - 6.2 5.7 9.5 16 4.4 9.1 1.7 1 1 0 1 1 1 0 Integral peroxisomal membrane peroxin Leu_Phe_trans PF03588.14 CBZ28935.1 - 0.0053 16.3 0.1 0.79 9.2 0.0 2.2 2 0 0 2 2 2 2 Leucyl/phenylalanyl-tRNA protein transferase FTHFS PF01268.19 CBZ28936.1 - 6e-253 840.1 0.0 6.8e-253 839.9 0.0 1.0 1 0 0 1 1 1 1 Formate--tetrahydrofolate ligase RRM_1 PF00076.22 CBZ28937.1 - 1.1e-15 57.2 0.0 2.2e-15 56.2 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 CBZ28937.1 - 0.0014 18.6 0.0 0.0023 17.9 0.0 1.3 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif DUF3138 PF11336.8 CBZ28937.1 - 0.011 14.4 2.1 0.016 13.8 2.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) CPSF100_C PF13299.6 CBZ28937.1 - 0.066 13.4 0.5 0.098 12.8 0.5 1.2 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal PHM7_cyt PF14703.6 CBZ28937.1 - 0.072 13.3 0.3 16 5.7 0.0 2.2 2 0 0 2 2 2 0 Cytosolic domain of 10TM putative phosphate transporter DUF4589 PF15252.6 CBZ28937.1 - 0.12 12.4 0.1 0.14 12.1 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4589) AAA PF00004.29 CBZ28940.1 - 1.1e-13 51.8 0.0 2.1e-13 50.8 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rep_fac_C PF08542.11 CBZ28940.1 - 2.3e-11 43.9 0.0 4.1e-11 43.1 0.0 1.4 1 0 0 1 1 1 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.6 CBZ28940.1 - 1.6e-09 37.8 0.0 6.3e-06 26.1 0.0 2.2 2 0 0 2 2 2 2 DNA polymerase III, delta subunit AAA_11 PF13086.6 CBZ28940.1 - 1.2e-05 25.3 0.0 3.3e-05 23.8 0.0 1.7 1 1 1 2 2 2 1 AAA domain AAA_22 PF13401.6 CBZ28940.1 - 3.8e-05 24.0 0.1 0.00039 20.7 0.1 2.3 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.12 CBZ28940.1 - 3.9e-05 23.5 0.0 0.0002 21.1 0.0 2.1 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 CBZ28940.1 - 4.8e-05 23.8 0.7 0.0011 19.4 0.0 2.6 2 1 0 3 3 3 1 AAA ATPase domain Rad17 PF03215.15 CBZ28940.1 - 0.00011 22.1 0.0 0.0002 21.3 0.0 1.3 1 0 0 1 1 1 1 Rad17 P-loop domain DUF2075 PF09848.9 CBZ28940.1 - 0.003 16.8 0.0 0.0041 16.4 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_30 PF13604.6 CBZ28940.1 - 0.0038 17.0 0.0 0.0071 16.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain ResIII PF04851.15 CBZ28940.1 - 0.013 15.5 0.0 0.035 14.1 0.0 1.7 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit AAA_5 PF07728.14 CBZ28940.1 - 0.026 14.5 0.0 0.057 13.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_33 PF13671.6 CBZ28940.1 - 0.041 14.0 0.0 0.082 13.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 CBZ28940.1 - 0.043 13.2 0.1 0.1 11.9 0.1 1.8 1 1 0 1 1 1 0 Magnesium chelatase, subunit ChlI DEAD PF00270.29 CBZ28940.1 - 0.049 13.4 0.1 0.62 9.8 0.0 2.2 1 1 1 2 2 2 0 DEAD/DEAH box helicase DUF815 PF05673.13 CBZ28940.1 - 0.054 12.6 0.0 0.086 12.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_24 PF13479.6 CBZ28940.1 - 0.06 13.1 0.0 0.18 11.5 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_19 PF13245.6 CBZ28940.1 - 0.065 13.6 0.0 0.18 12.1 0.0 1.8 1 1 0 1 1 1 0 AAA domain AAA_28 PF13521.6 CBZ28940.1 - 0.086 13.1 0.0 0.19 12.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain Viral_helicase1 PF01443.18 CBZ28940.1 - 0.093 12.5 0.0 0.2 11.3 0.0 1.7 1 1 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_3 PF07726.11 CBZ28940.1 - 0.19 11.6 0.0 0.89 9.4 0.0 2.0 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 CBZ28940.1 - 0.24 10.9 0.0 0.4 10.2 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_23 PF13476.6 CBZ28940.1 - 0.26 11.8 0.0 0.39 11.2 0.0 1.2 1 0 0 1 1 1 0 AAA domain ubiquitin PF00240.23 CBZ28943.1 - 8.4e-05 22.2 0.0 0.00014 21.6 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family rRNA_methylase PF06962.12 CBZ28943.1 - 0.097 12.6 0.0 0.15 12.0 0.0 1.2 1 0 0 1 1 1 0 Putative rRNA methylase DUF4152 PF13680.6 CBZ28943.1 - 0.1 12.0 0.0 0.13 11.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4152) TPR_12 PF13424.6 CBZ28944.1 - 0.0014 18.8 1.3 0.0014 18.8 1.3 2.2 2 1 1 3 3 3 2 Tetratricopeptide repeat DUF3156 PF11354.8 CBZ28944.1 - 0.013 15.4 0.0 0.03 14.2 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3156) TPR_16 PF13432.6 CBZ28944.1 - 6.2 7.6 10.2 3.4 8.4 0.8 4.0 2 1 2 4 4 4 0 Tetratricopeptide repeat UbiA PF01040.18 CBZ28945.1 - 0.041 13.2 2.2 0.22 10.8 0.8 2.2 2 0 0 2 2 2 0 UbiA prenyltransferase family TPT PF03151.16 CBZ28946.1 - 1.6e-13 50.6 18.6 2e-13 50.4 18.6 1.0 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 CBZ28946.1 - 0.0018 18.5 11.6 0.0018 18.5 11.6 2.9 2 1 0 2 2 2 1 EamA-like transporter family SH3_9 PF14604.6 CBZ28947.1 - 2.2e-06 27.4 0.0 3.3e-06 26.9 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 CBZ28947.1 - 1e-05 25.1 0.0 1.5e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 CBZ28947.1 - 6.8e-05 22.4 0.0 0.00013 21.5 0.0 1.5 1 0 0 1 1 1 1 SH3 domain CortBP2 PF09727.9 CBZ28947.1 - 0.0043 17.0 0.3 0.0061 16.5 0.3 1.1 1 0 0 1 1 1 1 Cortactin-binding protein-2 Tmemb_9 PF05434.11 CBZ28947.1 - 0.29 11.0 0.8 0.46 10.4 0.8 1.2 1 0 0 1 1 1 0 TMEM9 LRR_6 PF13516.6 CBZ28948.1 - 0.017 15.2 0.2 0.12 12.5 0.0 2.4 2 0 0 2 2 2 0 Leucine Rich repeat GRAM PF02893.20 CBZ28950.1 - 4.3e-11 42.7 0.1 7.4e-11 41.9 0.1 1.4 1 0 0 1 1 1 1 GRAM domain SPA PF08616.10 CBZ28951.1 - 7.1e-29 100.1 0.0 1.3e-28 99.2 0.0 1.5 1 0 0 1 1 1 1 Stabilization of polarity axis Avl9 PF09794.9 CBZ28951.1 - 0.00014 20.7 0.0 0.054 12.2 0.0 2.2 1 1 1 2 2 2 2 Transport protein Avl9 DENN PF02141.21 CBZ28951.1 - 0.022 14.7 0.2 0.063 13.2 0.0 1.9 2 0 0 2 2 2 0 DENN (AEX-3) domain DUF2347 PF09804.9 CBZ28951.1 - 0.056 13.0 0.0 0.091 12.3 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2347) TPR_1 PF00515.28 CBZ28952.1 - 1.7e-26 90.9 8.4 1.6e-08 34.0 1.0 4.0 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.17 CBZ28952.1 - 3.1e-19 67.5 14.1 3.5e-07 29.8 0.0 4.8 5 0 0 5 5 4 3 Tetratricopeptide repeat TPR_8 PF13181.6 CBZ28952.1 - 8.9e-16 56.7 3.6 5.5e-05 23.1 0.7 3.7 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.6 CBZ28952.1 - 1.7e-13 50.0 8.2 3.3e-07 29.9 0.7 3.8 2 1 2 4 4 4 3 TPR repeat TPR_17 PF13431.6 CBZ28952.1 - 5.7e-11 42.0 2.4 0.00043 20.5 0.3 4.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 CBZ28952.1 - 1.1e-08 35.6 3.4 7.6e-05 23.3 0.0 3.2 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 CBZ28952.1 - 1.2e-08 35.1 3.4 2.3e-05 24.6 0.2 2.9 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.6 CBZ28952.1 - 1e-07 32.1 0.1 0.092 13.6 0.1 3.7 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.6 CBZ28952.1 - 2e-07 30.5 0.3 0.07 13.2 0.0 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat SGT1 PF07093.11 CBZ28952.1 - 2.7e-07 29.4 1.9 4e-07 28.9 1.9 1.2 1 0 0 1 1 1 1 SGT1 protein STI1 PF17830.1 CBZ28952.1 - 4.4e-06 26.5 8.6 0.00092 19.1 0.3 3.3 3 0 0 3 3 2 2 STI1 domain TPR_9 PF13371.6 CBZ28952.1 - 7e-05 22.9 0.0 0.018 15.2 0.0 2.5 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.6 CBZ28952.1 - 0.00012 22.5 3.1 0.026 15.0 0.5 3.2 2 1 1 3 3 2 1 Tetratricopeptide repeat TPR_10 PF13374.6 CBZ28952.1 - 0.0013 18.5 6.7 5.3 7.0 0.0 3.9 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_6 PF13174.6 CBZ28952.1 - 0.0018 18.8 3.6 1.6 9.5 0.0 3.7 4 0 0 4 4 3 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 CBZ28952.1 - 0.014 15.5 1.7 15 5.8 0.0 3.4 3 0 0 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat ANAPC3 PF12895.7 CBZ28952.1 - 0.02 15.1 3.4 0.3 11.3 0.4 2.6 1 1 1 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TOM20_plant PF06552.12 CBZ28952.1 - 0.046 13.5 1.9 2.3 8.0 0.2 3.0 1 1 1 2 2 2 0 Plant specific mitochondrial import receptor subunit TOM20 RIG-I_C PF18119.1 CBZ28952.1 - 0.15 12.1 1.8 2 8.4 1.5 2.6 1 1 1 2 2 2 0 RIG-I receptor C-terminal domain Ins_allergen_rp PF06757.13 CBZ28952.1 - 0.19 11.7 1.8 4.5 7.2 0.0 2.9 4 0 0 4 4 4 0 Insect allergen related repeat, nitrile-specifier detoxification MIT PF04212.18 CBZ28952.1 - 0.67 10.1 10.3 2.3 8.4 1.7 3.8 3 1 0 3 3 3 0 MIT (microtubule interacting and transport) domain DSBA PF01323.20 CBZ28953.1 - 0.015 15.1 0.5 0.023 14.5 0.5 1.2 1 0 0 1 1 1 0 DSBA-like thioredoxin domain Methyltransf_5 PF01795.19 CBZ28953.1 - 0.024 14.2 0.4 0.035 13.6 0.4 1.2 1 0 0 1 1 1 0 MraW methylase family TMA7 PF09072.10 CBZ28954.1 - 2.7e-15 56.9 14.9 3e-15 56.8 14.9 1.0 1 0 0 1 1 1 1 Translation machinery associated TMA7 FixG_C PF11614.8 CBZ28955.1 - 0.05 13.8 0.0 0.1 12.8 0.0 1.4 1 0 0 1 1 1 0 IG-like fold at C-terminal of FixG, putative oxidoreductase PTS_EIIC PF02378.18 CBZ28955.1 - 0.067 12.2 0.2 0.08 12.0 0.2 1.1 1 0 0 1 1 1 0 Phosphotransferase system, EIIC Sod_Fe_C PF02777.18 CBZ28956.1 - 1.2e-06 28.6 0.0 2.7e-06 27.5 0.0 1.6 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.22 CBZ28956.1 - 1.5e-06 28.6 0.0 2.3e-06 28.0 0.0 1.3 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain zf-CCCH PF00642.24 CBZ28957.1 - 1.9e-06 27.6 1.7 1.9e-06 27.6 1.7 2.3 3 0 0 3 3 3 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 CBZ28957.1 - 4.7e-05 23.1 2.5 7.8e-05 22.4 2.5 1.4 1 0 0 1 1 1 1 CCCH-type zinc finger zf_CCCH_4 PF18345.1 CBZ28957.1 - 4.9e-05 23.2 4.5 4.9e-05 23.2 4.5 1.7 2 0 0 2 2 2 1 Zinc finger domain zf-CCCH_2 PF14608.6 CBZ28957.1 - 0.092 13.3 1.9 0.18 12.3 1.9 1.5 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger DUF872 PF05915.12 CBZ28958.1 - 3e-07 30.6 0.2 4.2e-07 30.1 0.2 1.4 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF872) Cpn60_TCP1 PF00118.24 CBZ28961.1 - 2.1e-69 234.5 7.8 2.3e-68 231.0 7.8 1.9 1 1 0 1 1 1 1 TCP-1/cpn60 chaperonin family TcpQ PF10671.9 CBZ28961.1 - 0.15 12.2 0.4 4.2 7.6 0.0 2.9 3 0 0 3 3 3 0 Toxin co-regulated pilus biosynthesis protein Q RabGAP-TBC PF00566.18 CBZ28963.1 - 1.9e-34 119.2 1.2 7.7e-34 117.2 1.2 1.8 1 1 0 1 1 1 1 Rab-GTPase-TBC domain DUF4597 PF15366.6 CBZ28966.1 - 0.018 14.8 1.7 0.033 13.9 0.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4597) PPR_2 PF13041.6 CBZ28967.1 - 0.0013 18.9 0.0 48 4.2 0.0 5.2 6 0 0 6 6 6 0 PPR repeat family PPR PF01535.20 CBZ28967.1 - 0.002 18.2 0.2 25 5.4 0.0 5.6 7 0 0 7 7 7 1 PPR repeat TPR_14 PF13428.6 CBZ28967.1 - 0.034 15.0 13.6 40 5.4 0.1 6.9 6 1 1 7 7 7 0 Tetratricopeptide repeat ANAPC3 PF12895.7 CBZ28967.1 - 0.063 13.5 0.2 3.9 7.8 0.0 3.4 3 0 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.6 CBZ28967.1 - 0.28 11.7 9.2 21 5.7 0.3 5.3 4 1 1 5 5 5 0 Tetratricopeptide repeat OST_P2 PF18235.1 CBZ28968.1 - 0.12 12.3 0.0 2.3 8.2 0.0 2.4 3 0 0 3 3 3 0 Oligosaccharyltransferase Peripheral 2 domain Aldedh PF00171.22 CBZ28969.1 - 2.4e-120 402.2 0.1 3e-120 401.8 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.11 CBZ28969.1 - 0.023 14.2 0.0 0.049 13.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1487) Med27 PF11571.8 CBZ28969.1 - 0.065 13.6 0.0 0.15 12.4 0.0 1.6 1 0 0 1 1 1 0 Mediator complex subunit 27 Pkinase PF00069.25 CBZ28970.1 - 5.8e-52 176.6 0.0 8.5e-52 176.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ28970.1 - 6.1e-18 65.0 0.0 7.6e-18 64.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 CBZ28970.1 - 1.9e-06 27.4 0.1 3.1e-06 26.7 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 CBZ28970.1 - 0.00057 19.9 0.1 0.00083 19.4 0.1 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.6 CBZ28970.1 - 0.0021 17.4 0.0 0.0046 16.3 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 CBZ28970.1 - 0.0069 15.2 0.1 0.011 14.5 0.1 1.2 1 0 0 1 1 1 1 Fungal protein kinase CENP-Q PF13094.6 CBZ28971.1 - 6.9 6.8 30.4 0.027 14.7 8.0 2.8 2 1 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit PI-PLC-X PF00388.19 CBZ28974.1 - 4e-59 198.4 0.0 8e-59 197.4 0.0 1.5 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.19 CBZ28974.1 - 2.7e-33 114.7 0.0 5.1e-33 113.8 0.0 1.5 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain C2 PF00168.30 CBZ28974.1 - 2e-17 63.4 0.0 8.2e-17 61.4 0.0 2.1 1 0 0 1 1 1 1 C2 domain EF-hand_1 PF00036.32 CBZ28974.1 - 3.3e-10 38.8 0.1 0.0048 16.4 0.0 3.7 3 0 0 3 3 3 3 EF hand EF-hand_7 PF13499.6 CBZ28974.1 - 4.1e-09 36.8 0.5 5.2e-05 23.6 0.1 2.8 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 CBZ28974.1 - 5.6e-07 28.8 1.2 0.0039 16.6 0.1 3.1 3 0 0 3 3 3 2 EF hand EF-hand_8 PF13833.6 CBZ28974.1 - 2.3e-06 27.3 5.7 0.00087 19.1 0.8 3.9 3 1 1 4 4 4 3 EF-hand domain pair EF-hand_6 PF13405.6 CBZ28974.1 - 3.1e-06 26.7 0.2 0.53 10.4 0.1 4.1 3 0 0 3 3 3 2 EF-hand domain EF-hand_10 PF14788.6 CBZ28974.1 - 6.9e-05 22.6 0.1 0.00015 21.6 0.1 1.6 1 0 0 1 1 1 1 EF hand ATG13 PF10033.9 CBZ28974.1 - 0.0081 15.9 0.1 0.016 14.9 0.1 1.4 1 0 0 1 1 1 1 Autophagy-related protein 13 GDPD PF03009.17 CBZ28974.1 - 0.017 14.9 0.1 0.041 13.6 0.1 1.6 1 0 0 1 1 1 0 Glycerophosphoryl diester phosphodiesterase family EF-hand_4 PF12763.7 CBZ28974.1 - 0.074 13.0 0.5 2.5 8.1 0.7 2.6 1 1 1 2 2 2 0 Cytoskeletal-regulatory complex EF hand zf-CHCC PF10276.9 CBZ28975.1 - 0.00024 21.1 2.5 0.00024 21.1 2.5 1.9 2 0 0 2 2 2 1 Zinc-finger domain Gp_dh_C PF02800.20 CBZ28976.1 - 2.6e-64 215.6 0.1 4.3e-64 214.9 0.1 1.3 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.24 CBZ28976.1 - 6.3e-31 106.7 0.1 1.3e-30 105.7 0.1 1.5 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain DapB_N PF01113.20 CBZ28976.1 - 0.0037 17.4 0.4 0.012 15.7 0.4 2.0 1 1 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus GFO_IDH_MocA PF01408.22 CBZ28976.1 - 0.023 15.5 0.1 0.045 14.6 0.1 1.5 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold AvrM_N PF18247.1 CBZ28976.1 - 0.24 11.3 2.5 2.8 8.0 0.1 2.6 3 0 0 3 3 3 0 Flax-rust effector AvrM N-terminal domain DUF2817 PF10994.8 CBZ28977.1 - 1.7e-106 356.5 0.1 2e-106 356.2 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2817) AstE_AspA PF04952.14 CBZ28977.1 - 1.7e-05 24.0 0.0 3e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 Succinylglutamate desuccinylase / Aspartoacylase family TPR_1 PF00515.28 CBZ28979.1 - 3.9e-103 333.5 32.4 1.5e-08 34.1 0.5 14.8 15 0 0 15 15 15 14 Tetratricopeptide repeat TPR_2 PF07719.17 CBZ28979.1 - 1.9e-83 268.0 49.8 1.8e-06 27.6 0.9 15.3 15 0 0 15 15 15 14 Tetratricopeptide repeat TPR_11 PF13414.6 CBZ28979.1 - 1.2e-65 216.9 34.4 1e-08 34.7 4.0 14.0 5 2 9 14 14 14 12 TPR repeat TPR_8 PF13181.6 CBZ28979.1 - 1.5e-57 187.0 21.8 3.2e-05 23.8 0.1 14.5 15 0 0 15 15 15 11 Tetratricopeptide repeat TPR_16 PF13432.6 CBZ28979.1 - 6.7e-50 167.5 51.5 2.7e-09 37.5 0.2 10.4 7 3 3 10 10 10 9 Tetratricopeptide repeat TPR_17 PF13431.6 CBZ28979.1 - 4.5e-44 145.7 27.9 5.5e-06 26.4 0.0 12.9 13 0 0 13 13 13 9 Tetratricopeptide repeat TPR_9 PF13371.6 CBZ28979.1 - 2.2e-40 136.7 39.1 1.2e-05 25.4 0.0 10.7 4 3 6 11 11 11 10 Tetratricopeptide repeat TPR_12 PF13424.6 CBZ28979.1 - 1.9e-36 124.2 50.1 6.6e-08 32.7 3.9 11.1 6 3 4 11 11 11 7 Tetratricopeptide repeat TPR_7 PF13176.6 CBZ28979.1 - 3.4e-27 92.4 29.2 0.055 13.5 0.0 13.7 13 0 0 13 13 13 7 Tetratricopeptide repeat TPR_6 PF13174.6 CBZ28979.1 - 2.7e-22 77.9 33.6 0.44 11.3 0.0 13.8 14 0 0 14 14 13 6 Tetratricopeptide repeat TPR_14 PF13428.6 CBZ28979.1 - 2.5e-19 68.3 43.8 0.055 14.3 0.1 14.0 3 2 11 14 14 14 6 Tetratricopeptide repeat TPR_19 PF14559.6 CBZ28979.1 - 3.2e-18 66.0 28.1 6.2e-06 26.6 1.7 9.4 4 2 6 11 11 11 8 Tetratricopeptide repeat TPR_10 PF13374.6 CBZ28979.1 - 6.6e-10 38.5 42.8 0.15 12.0 0.4 12.1 13 0 0 13 13 13 4 Tetratricopeptide repeat SHNi-TPR PF10516.9 CBZ28979.1 - 4.7e-08 32.3 24.6 2.1 7.9 0.0 11.7 13 0 0 13 13 13 1 SHNi-TPR ANAPC3 PF12895.7 CBZ28979.1 - 5e-05 23.5 32.0 0.01 16.0 0.8 7.5 3 3 6 9 9 9 2 Anaphase-promoting complex, cyclosome, subunit 3 NARP1 PF12569.8 CBZ28979.1 - 0.00047 19.2 9.2 0.29 10.0 0.0 4.8 2 1 3 5 5 5 2 NMDA receptor-regulated protein 1 MIT PF04212.18 CBZ28979.1 - 0.001 19.1 28.4 0.14 12.3 0.1 9.2 9 1 0 9 9 9 1 MIT (microtubule interacting and transport) domain DUF3856 PF12968.7 CBZ28979.1 - 0.0014 18.7 10.0 34 4.5 0.0 7.6 5 3 3 8 8 8 0 Domain of Unknown Function (DUF3856) Coatomer_E PF04733.14 CBZ28979.1 - 0.0031 17.0 0.6 4.1 6.7 0.0 3.8 4 1 0 4 4 4 1 Coatomer epsilon subunit BTAD PF03704.17 CBZ28979.1 - 0.014 15.8 27.9 2.1 8.7 0.0 6.9 4 2 2 7 7 7 0 Bacterial transcriptional activator domain ANAPC5 PF12862.7 CBZ28979.1 - 0.081 13.0 3.3 11 6.2 0.3 4.6 4 1 0 4 4 4 0 Anaphase-promoting complex subunit 5 TPR_4 PF07721.14 CBZ28979.1 - 3.2 8.6 22.4 4.5 8.2 1.4 8.1 8 0 0 8 8 8 0 Tetratricopeptide repeat LSM PF01423.22 CBZ28980.1 - 2e-08 33.8 0.1 2.7e-08 33.4 0.1 1.2 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 CBZ28980.1 - 0.089 12.9 0.0 0.13 12.5 0.0 1.3 1 0 0 1 1 1 0 Ataxin 2 SM domain KH_8 PF17903.1 CBZ28981.1 - 8.5e-26 89.9 0.0 1.7e-25 88.9 0.0 1.5 1 0 0 1 1 1 1 Krr1 KH1 domain DUF1513 PF07433.11 CBZ28982.1 - 0.19 10.8 0.0 0.19 10.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1513) DUF21 PF01595.20 CBZ28983.1 - 2.4e-27 95.7 2.4 1.5e-26 93.2 3.3 1.8 2 0 0 2 2 2 1 Cyclin M transmembrane N-terminal domain CBS PF00571.28 CBZ28983.1 - 0.00041 20.8 0.0 0.45 11.0 0.0 2.7 2 0 0 2 2 2 2 CBS domain U-box PF04564.15 CBZ28983.1 - 0.14 12.4 0.0 3.1 8.0 0.0 2.8 3 0 0 3 3 3 0 U-box domain eIF-3_zeta PF05091.12 CBZ28984.1 - 3.6e-92 310.0 0.0 4.1e-92 309.8 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Pkinase PF00069.25 CBZ28985.1 - 4.4e-66 223.0 0.0 6.3e-66 222.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ28985.1 - 5.8e-45 153.6 0.0 8.8e-45 153.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CBZ28985.1 - 0.0024 16.7 0.0 0.005 15.7 0.0 1.5 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 CBZ28985.1 - 0.025 13.9 0.0 0.046 13.0 0.0 1.3 1 0 0 1 1 1 0 Kinase-like FTA2 PF13095.6 CBZ28985.1 - 0.2 11.2 0.0 0.37 10.4 0.0 1.3 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 Kinesin PF00225.23 CBZ28986.1 - 6.7e-82 275.1 0.0 6.7e-82 275.1 0.0 3.0 3 0 0 3 3 3 1 Kinesin motor domain Microtub_bd PF16796.5 CBZ28986.1 - 2e-19 70.0 0.1 1.2e-18 67.4 0.0 2.4 2 0 0 2 2 2 1 Microtubule binding PKcGMP_CC PF16808.5 CBZ28986.1 - 0.0033 17.2 1.0 0.0033 17.2 1.0 7.4 9 0 0 9 9 9 1 Coiled-coil N-terminus of cGMP-dependent protein kinase tRNA_m1G_MT PF01746.21 CBZ28987.1 - 1.4e-17 64.0 0.0 2.5e-17 63.2 0.0 1.3 1 0 0 1 1 1 1 tRNA (Guanine-1)-methyltransferase GHMP_kinases_N PF00288.26 CBZ28988.1 - 3.2e-08 33.7 1.7 8.5e-08 32.3 1.7 1.8 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 CBZ28988.1 - 4.6e-07 30.1 0.1 4.6e-07 30.1 0.1 1.8 2 0 0 2 2 2 1 GHMP kinases C terminal PPR_3 PF13812.6 CBZ28990.1 - 0.01 15.9 0.0 2 8.5 0.0 4.1 5 0 0 5 5 5 1 Pentatricopeptide repeat domain TPR_14 PF13428.6 CBZ28990.1 - 1.9 9.5 0.0 1.9 9.5 0.0 4.4 4 1 0 4 4 4 0 Tetratricopeptide repeat SAM_decarbox PF01536.16 CBZ28991.1 - 7.9e-88 294.8 0.0 9.3e-88 294.6 0.0 1.0 1 0 0 1 1 1 1 Adenosylmethionine decarboxylase SAM_decarbox PF01536.16 CBZ28992.1 - 1.5e-09 37.3 0.1 0.00092 18.3 0.1 2.2 2 0 0 2 2 2 2 Adenosylmethionine decarboxylase DUF1381 PF07129.11 CBZ28992.1 - 0.19 11.6 0.1 0.19 11.6 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1381) tRNA-synt_1 PF00133.22 CBZ28993.1 - 1.6e-195 650.9 0.0 1.8e-194 647.4 0.0 2.0 1 1 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 CBZ28993.1 - 5.2e-37 127.2 0.0 9.1e-37 126.4 0.0 1.4 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA Val_tRNA-synt_C PF10458.9 CBZ28993.1 - 6.8e-16 58.3 0.7 1.6e-15 57.1 0.7 1.7 1 0 0 1 1 1 1 Valyl tRNA synthetase tRNA binding arm tRNA-synt_1g PF09334.11 CBZ28993.1 - 2.1e-14 53.1 0.5 3.3e-07 29.4 0.1 3.8 3 1 0 3 3 3 3 tRNA synthetases class I (M) tRNA-synt_1_2 PF13603.6 CBZ28993.1 - 1.4e-08 34.4 0.0 0.00012 21.6 0.0 2.7 1 1 1 2 2 2 2 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1e PF01406.19 CBZ28993.1 - 0.072 12.4 0.6 2.4 7.4 0.1 2.9 3 0 0 3 3 3 0 tRNA synthetases class I (C) catalytic domain tRNA-synt_1b PF00579.25 CBZ28993.1 - 0.094 12.0 0.2 0.25 10.6 0.0 1.7 2 0 0 2 2 2 0 tRNA synthetases class I (W and Y) ADC PF06314.11 CBZ28993.1 - 0.1 12.2 0.0 0.21 11.1 0.0 1.4 1 0 0 1 1 1 0 Acetoacetate decarboxylase (ADC) MIS13 PF08202.11 CBZ28993.1 - 0.14 11.4 0.0 0.28 10.4 0.0 1.4 1 0 0 1 1 1 0 Mis12-Mtw1 protein family ABC_tran_CTD PF16326.5 CBZ28993.1 - 0.15 12.3 1.2 0.5 10.6 1.2 1.9 1 0 0 1 1 1 0 ABC transporter C-terminal domain TRAP_beta PF05753.14 CBZ28995.1 - 2.6e-08 33.5 1.5 4.7e-07 29.4 1.5 2.5 1 1 0 1 1 1 1 Translocon-associated protein beta (TRAPB) DUF11 PF01345.18 CBZ28995.1 - 1.5e-07 31.7 0.9 2.8e-07 30.8 0.9 1.5 1 0 0 1 1 1 1 Domain of unknown function DUF11 CARDB PF07705.11 CBZ28995.1 - 9.3e-05 22.6 0.4 0.00014 22.1 0.4 1.3 1 0 0 1 1 1 1 CARDB TPH PF13868.6 CBZ28997.1 - 2.4e-36 125.0 142.6 2.4e-36 125.0 142.6 1.8 1 1 0 1 1 1 1 Trichohyalin-plectin-homology domain YfhO PF09586.10 CBZ28997.1 - 2.1 6.5 3.7 2.9 6.0 3.7 1.2 1 0 0 1 1 1 0 Bacterial membrane protein YfhO RRM_1 PF00076.22 CBZ28998.1 - 1.3e-08 34.5 0.0 1.9e-08 34.0 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 CBZ28998.1 - 0.027 14.0 0.0 0.032 13.8 0.0 1.2 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) HMG-CoA_red PF00368.18 CBZ28999.1 - 2.4e-133 444.7 3.8 2.8e-133 444.5 3.8 1.0 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A reductase Ribosomal_S26e PF01283.19 CBZ29000.1 - 1.1e-35 122.4 4.4 1.1e-35 122.3 4.4 1.0 1 0 0 1 1 1 1 Ribosomal protein S26e FKBP_C PF00254.28 CBZ29001.1 - 0.097 13.0 0.0 0.26 11.6 0.0 1.7 1 0 0 1 1 1 0 FKBP-type peptidyl-prolyl cis-trans isomerase DUF4250 PF14056.6 CBZ29001.1 - 7.2 6.6 7.7 1.6 8.8 0.6 3.1 3 1 0 3 3 3 0 Domain of unknown function (DUF4250) tRNA-synt_1c PF00749.21 CBZ29005.1 - 1.2e-102 343.1 0.1 1.6e-102 342.6 0.1 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.18 CBZ29005.1 - 2.3e-35 122.1 0.1 4.7e-35 121.0 0.1 1.6 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain HA2 PF04408.23 CBZ29006.1 - 1.3e-13 51.2 0.0 1.3e-13 51.2 0.0 3.0 2 1 0 2 2 1 1 Helicase associated domain (HA2) Helicase_C PF00271.31 CBZ29006.1 - 1e-10 42.0 0.2 8.2e-10 39.0 0.0 2.6 3 0 0 3 3 3 1 Helicase conserved C-terminal domain DEAD PF00270.29 CBZ29006.1 - 1.1e-07 31.7 0.0 1.6e-06 28.0 0.0 2.6 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 CBZ29006.1 - 1.7e-05 25.1 2.8 5.2e-05 23.5 0.0 2.9 3 0 0 3 3 3 1 AAA domain OB_NTP_bind PF07717.16 CBZ29006.1 - 3.5e-05 24.1 0.0 7.7e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold AAA_19 PF13245.6 CBZ29006.1 - 0.00076 19.8 0.6 0.0031 17.9 0.0 2.3 2 1 0 2 2 1 1 AAA domain ATPase PF06745.13 CBZ29006.1 - 0.033 13.5 0.0 0.15 11.4 0.0 2.1 1 0 0 1 1 1 0 KaiC T2SSE PF00437.20 CBZ29006.1 - 0.061 12.4 6.7 0.17 11.0 6.7 1.6 1 1 0 1 1 1 0 Type II/IV secretion system protein ResIII PF04851.15 CBZ29006.1 - 0.11 12.5 5.7 0.15 12.0 0.1 3.4 2 1 1 3 3 3 0 Type III restriction enzyme, res subunit AAA_16 PF13191.6 CBZ29006.1 - 0.14 12.6 1.9 0.39 11.1 0.0 2.6 2 0 0 2 2 2 0 AAA ATPase domain DUF87 PF01935.17 CBZ29006.1 - 1.7 8.7 4.3 21 5.1 0.0 3.4 3 0 0 3 3 3 0 Helicase HerA, central domain Ank_2 PF12796.7 CBZ29007.1 - 6.6e-32 109.9 2.9 1.1e-11 45.1 0.0 4.1 1 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CBZ29007.1 - 1.3e-31 108.5 4.0 2.9e-09 37.3 0.0 6.3 2 2 4 6 6 6 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 CBZ29007.1 - 7.2e-27 90.5 1.0 0.00019 21.6 0.0 8.0 8 0 0 8 8 8 7 Ankyrin repeat Ank_5 PF13857.6 CBZ29007.1 - 3.5e-24 84.6 5.6 1.4e-08 34.9 0.2 6.2 3 1 4 7 7 7 5 Ankyrin repeats (many copies) Ank PF00023.30 CBZ29007.1 - 1.5e-22 79.0 8.1 0.00045 20.6 0.0 7.1 7 0 0 7 7 7 6 Ankyrin repeat FAP206 PF12018.8 CBZ29007.1 - 0.95 8.9 4.1 0.56 9.7 2.0 1.6 2 0 0 2 2 2 0 Domain of unknown function Sensor PF13796.6 CBZ29008.1 - 0.0048 17.0 0.5 0.0066 16.5 0.5 1.2 1 0 0 1 1 1 1 Putative sensor Metallophos PF00149.28 CBZ29009.1 - 5.9e-10 40.0 0.1 9.1e-10 39.4 0.1 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase DUF2561 PF10812.8 CBZ29009.1 - 0.039 14.0 1.1 0.13 12.3 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2561) ubiquitin PF00240.23 CBZ29011.1 - 3.3e-14 52.4 0.0 6.4e-14 51.5 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family XPC-binding PF09280.11 CBZ29011.1 - 4.6e-14 51.9 0.3 9e-14 51.0 0.3 1.5 1 0 0 1 1 1 1 XPC-binding domain UBA PF00627.31 CBZ29011.1 - 1.3e-11 44.2 4.9 4.4e-07 29.7 0.8 2.5 2 0 0 2 2 2 2 UBA/TS-N domain Rad60-SLD PF11976.8 CBZ29011.1 - 1.8e-07 30.9 0.5 3.7e-07 29.9 0.2 1.7 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like UBA_3 PF09288.10 CBZ29011.1 - 0.0098 15.7 0.0 0.03 14.1 0.0 1.7 2 0 0 2 2 2 1 Fungal ubiquitin-associated domain Ubiquitin_4 PF18036.1 CBZ29011.1 - 0.048 13.7 0.6 4.4 7.4 0.6 2.4 1 1 0 1 1 1 0 Ubiquitin-like domain MCM_N PF14551.6 CBZ29011.1 - 0.066 13.8 0.9 0.11 13.1 0.1 1.7 2 0 0 2 2 2 0 MCM N-terminal domain MORN PF02493.20 CBZ29012.1 - 1.2e-91 295.4 106.0 5.9e-10 38.4 2.1 15.1 15 0 0 15 15 15 15 MORN repeat Peptidase_S55 PF05580.12 CBZ29012.1 - 0.16 11.9 9.9 1.3 8.9 0.2 5.2 3 2 2 5 5 5 0 SpoIVB peptidase S55 BAR PF03114.18 CBZ29013.1 - 0.00012 21.8 0.2 0.00016 21.4 0.2 1.2 1 0 0 1 1 1 1 BAR domain GREB1 PF15782.5 CBZ29014.1 - 5.8 3.9 6.2 6.9 3.7 6.2 1.2 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Ribosomal_L6 PF00347.23 CBZ29015.1 - 7.5e-27 93.8 3.8 6.9e-15 55.5 0.7 2.1 2 0 0 2 2 2 2 Ribosomal protein L6 EF-hand_7 PF13499.6 CBZ29017.1 - 1.2e-37 128.1 12.7 2.8e-07 30.9 0.4 5.7 6 0 0 6 6 5 5 EF-hand domain pair EF-hand_1 PF00036.32 CBZ29017.1 - 9.1e-33 109.4 12.6 7.2e-05 22.1 0.0 10.4 10 0 0 10 10 10 7 EF hand EF-hand_6 PF13405.6 CBZ29017.1 - 1.8e-30 102.2 14.2 0.00017 21.3 0.1 10.0 10 0 0 10 10 10 7 EF-hand domain EF-hand_5 PF13202.6 CBZ29017.1 - 1.7e-25 87.3 12.4 0.0003 20.2 0.0 8.3 9 0 0 9 9 9 6 EF hand EF-hand_8 PF13833.6 CBZ29017.1 - 1.9e-15 56.4 14.9 0.85 9.5 0.2 10.2 9 1 1 10 10 10 7 EF-hand domain pair SPARC_Ca_bdg PF10591.9 CBZ29017.1 - 1.6e-09 38.1 0.2 0.095 13.0 0.0 5.5 5 1 0 5 5 5 2 Secreted protein acidic and rich in cysteine Ca binding region Tropomyosin PF00261.20 CBZ29017.1 - 0.039 13.3 0.2 0.099 12.0 0.0 1.7 2 0 0 2 2 2 0 Tropomyosin DUF3349 PF11829.8 CBZ29017.1 - 0.094 13.5 0.5 13 6.6 0.1 4.0 3 1 1 4 4 4 0 Protein of unknown function (DUF3349) RelB_N PF18506.1 CBZ29017.1 - 0.13 12.1 0.2 0.49 10.2 0.0 2.0 2 0 0 2 2 2 0 RelB Antitoxin alpha helical domain Caleosin PF05042.13 CBZ29017.1 - 0.31 10.9 1.8 14 5.6 0.0 4.3 6 1 0 6 6 6 0 Caleosin related protein Excalibur PF05901.11 CBZ29017.1 - 0.79 10.4 3.9 1.4e+02 3.2 0.1 4.4 4 0 0 4 4 4 0 Excalibur calcium-binding domain DUF3614 PF12267.8 CBZ29017.1 - 1.1 9.7 4.2 2.4 8.6 4.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3614) DUF4407 PF14362.6 CBZ29018.1 - 5.8 6.2 10.3 10 5.4 10.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) PGK PF00162.19 CBZ29019.1 - 6.4e-136 453.2 0.1 8.1e-136 452.9 0.1 1.1 1 0 0 1 1 1 1 Phosphoglycerate kinase PAS PF00989.25 CBZ29019.1 - 8.2e-07 29.0 0.0 3.1e-06 27.2 0.0 1.9 2 0 0 2 2 2 1 PAS fold PAS_4 PF08448.10 CBZ29019.1 - 0.00061 20.0 0.0 0.0028 17.9 0.0 2.0 2 0 0 2 2 2 1 PAS fold PAS_8 PF13188.7 CBZ29019.1 - 0.0007 19.6 0.0 0.0022 17.9 0.0 1.9 1 0 0 1 1 1 1 PAS domain PAS_9 PF13426.7 CBZ29019.1 - 0.0012 19.0 0.0 0.012 15.8 0.0 2.4 2 0 0 2 2 2 1 PAS domain bPH_1 PF08000.11 CBZ29019.1 - 0.14 12.3 0.2 0.27 11.3 0.2 1.4 1 0 0 1 1 1 0 Bacterial PH domain DUF2671 PF10877.8 CBZ29019.1 - 0.17 11.7 0.1 3.3 7.6 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2671) CAS_CSE1 PF03378.15 CBZ29020.1 - 9e-66 222.2 0.0 2.7e-65 220.6 0.0 1.9 2 0 0 2 2 2 1 CAS/CSE protein, C-terminus Cse1 PF08506.10 CBZ29020.1 - 5e-48 163.8 0.0 7.3e-48 163.3 0.0 1.3 1 0 0 1 1 1 1 Cse1 IBN_N PF03810.19 CBZ29020.1 - 0.0078 16.1 0.1 0.063 13.2 0.0 2.6 3 0 0 3 3 3 1 Importin-beta N-terminal domain Xpo1 PF08389.12 CBZ29020.1 - 0.018 15.1 1.5 8.5 6.4 0.0 3.8 3 2 1 4 4 4 0 Exportin 1-like protein MCM_N PF14551.6 CBZ29020.1 - 0.28 11.8 0.7 6.7 7.3 0.0 3.1 3 0 0 3 3 3 0 MCM N-terminal domain Dynein_heavy PF03028.15 CBZ29022.1 - 6.1e-07 29.6 0.0 1.4e-06 28.3 0.0 1.6 1 0 0 1 1 1 1 Dynein heavy chain region D6 P-loop domain WD40 PF00400.32 CBZ29022.1 - 1.4e-06 28.9 8.5 0.57 11.1 0.9 4.9 4 0 0 4 4 4 3 WD domain, G-beta repeat Tcp11 PF05794.13 CBZ29023.1 - 1.9e-29 103.0 5.0 1.9e-29 103.0 5.0 1.6 2 0 0 2 2 2 1 T-complex protein 11 MKT1_C PF12246.8 CBZ29024.1 - 3.7e-17 62.4 0.0 5.4e-17 61.8 0.0 1.3 1 0 0 1 1 1 1 Temperature dependent protein affecting M2 dsRNA replication MKT1_N PF12247.8 CBZ29024.1 - 5.3e-08 33.1 0.0 1.6e-07 31.6 0.0 1.8 1 0 0 1 1 1 1 Temperature dependent protein affecting M2 dsRNA replication DNA_ligase_A_M PF01068.21 CBZ29025.1 - 1.8e-54 184.5 0.0 2.7e-54 183.9 0.0 1.3 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.14 CBZ29025.1 - 9.4e-33 114.0 0.0 1.5e-32 113.3 0.0 1.3 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_C PF04679.15 CBZ29025.1 - 2.3e-23 82.7 0.0 5.9e-23 81.3 0.0 1.7 1 0 0 1 1 1 1 ATP dependent DNA ligase C terminal region RNA_ligase PF09414.10 CBZ29025.1 - 2.5e-05 24.7 0.1 4.2e-05 23.9 0.1 1.4 1 0 0 1 1 1 1 RNA ligase DNA_ligase_OB_2 PF14743.6 CBZ29025.1 - 0.18 11.9 0.6 4.7 7.3 0.0 2.6 2 0 0 2 2 2 0 DNA ligase OB-like domain TPR_16 PF13432.6 CBZ29027.1 - 1.1e-08 35.6 10.2 7.7e-05 23.3 0.2 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_17 PF13431.6 CBZ29027.1 - 7.3e-05 22.9 2.4 12 6.5 0.1 4.4 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_1 PF00515.28 CBZ29027.1 - 0.00031 20.4 2.4 5 7.1 0.1 4.2 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.6 CBZ29027.1 - 0.00035 21.2 12.8 0.049 14.5 0.1 4.8 3 2 2 5 5 5 2 Tetratricopeptide repeat TPR_9 PF13371.6 CBZ29027.1 - 0.00052 20.1 6.9 0.017 15.3 0.6 3.1 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.6 CBZ29027.1 - 0.00087 18.9 2.2 3.2 7.5 0.0 4.3 5 0 0 5 5 5 2 TPR repeat TTC5_OB PF16669.5 CBZ29027.1 - 0.014 15.1 0.1 0.15 11.8 0.1 2.1 1 1 0 1 1 1 0 Tetratricopeptide repeat protein 5 OB fold domain TPR_2 PF07719.17 CBZ29027.1 - 0.03 14.4 0.0 0.03 14.4 0.0 5.0 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_19 PF14559.6 CBZ29027.1 - 0.097 13.2 0.5 0.097 13.2 0.5 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.6 CBZ29027.1 - 1.9 8.9 5.5 20 5.7 0.0 3.9 5 0 0 5 5 5 0 Tetratricopeptide repeat Yippee-Mis18 PF03226.14 CBZ29028.1 - 9.4e-12 45.1 0.2 1.2e-11 44.7 0.2 1.1 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly RIG-I_C-RD PF11648.8 CBZ29028.1 - 0.0018 18.5 0.2 0.0026 18.0 0.2 1.2 1 0 0 1 1 1 1 C-terminal domain of RIG-I Pkinase PF00069.25 CBZ29029.1 - 1.5e-22 80.2 0.0 2e-22 79.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ29029.1 - 3.3e-12 46.2 0.0 4e-12 46.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CBZ29029.1 - 8.2e-11 41.3 0.0 1.1e-10 40.8 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 CBZ29029.1 - 0.057 13.3 0.0 0.13 12.2 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kinase-like PF14531.6 CBZ29029.1 - 0.15 11.3 0.0 0.27 10.5 0.0 1.3 1 0 0 1 1 1 0 Kinase-like zf-MIZ PF02891.20 CBZ29031.1 - 7.1e-19 67.3 6.1 1.2e-18 66.6 6.1 1.3 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger zf-Nse PF11789.8 CBZ29031.1 - 5.1e-06 26.2 3.3 1e-05 25.2 3.3 1.4 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit S-AdoMet_synt_C PF02773.16 CBZ29032.1 - 5.6e-66 220.7 0.0 1.2e-65 219.7 0.0 1.5 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, C-terminal domain S-AdoMet_synt_M PF02772.16 CBZ29032.1 - 2.4e-43 147.2 0.0 3.7e-42 143.4 0.0 2.1 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, central domain S-AdoMet_synt_N PF00438.20 CBZ29032.1 - 3.9e-40 136.5 0.2 3.9e-40 136.5 0.2 1.6 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, N-terminal domain Strep_pep PF14404.6 CBZ29032.1 - 0.027 14.7 0.0 0.088 13.1 0.0 1.8 1 0 0 1 1 1 0 Ribosomally synthesized peptide in Streptomyces species Rhodanese PF00581.20 CBZ29033.1 - 5.2e-06 26.9 0.0 9.5e-06 26.1 0.0 1.3 1 0 0 1 1 1 1 Rhodanese-like domain RF-1 PF00472.20 CBZ29034.1 - 1e-07 31.9 1.8 4.3e-07 29.9 0.0 2.5 3 1 0 3 3 3 1 RF-1 domain Terminase_4 PF05119.12 CBZ29034.1 - 0.043 14.2 0.0 0.11 13.0 0.0 1.6 1 0 0 1 1 1 0 Phage terminase, small subunit CARD PF00619.21 CBZ29034.1 - 0.078 13.0 0.1 0.66 10.1 0.0 2.3 2 0 0 2 2 2 0 Caspase recruitment domain TetR_C_15 PF17918.1 CBZ29034.1 - 0.34 11.7 5.9 0.17 12.7 2.9 2.1 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain p450 PF00067.22 CBZ29035.1 - 2.3e-45 155.2 0.1 3.1e-45 154.8 0.1 1.1 1 0 0 1 1 1 1 Cytochrome P450 Mago_nashi PF02792.14 CBZ29036.1 - 3.5e-59 199.0 0.2 4e-59 198.8 0.2 1.0 1 0 0 1 1 1 1 Mago nashi protein zf-CCCH PF00642.24 CBZ29037.1 - 5.5e-06 26.1 1.6 1.2e-05 25.0 1.6 1.6 1 1 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 CBZ29037.1 - 0.15 12.2 0.8 0.15 12.2 0.8 2.1 2 0 0 2 2 2 0 Zinc finger domain Jnk-SapK_ap_N PF09744.9 CBZ29037.1 - 0.18 12.0 6.3 0.25 11.5 6.3 1.2 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 Pkinase PF00069.25 CBZ29038.1 - 2.3e-34 118.9 0.0 1.2e-17 64.1 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ29038.1 - 3.7e-10 39.5 0.0 8.8e-06 25.2 0.0 2.4 2 0 0 2 2 2 2 Protein tyrosine kinase Ribosomal_S11 PF00411.19 CBZ29039.1 - 4.4e-47 159.0 1.7 5.6e-47 158.7 1.7 1.1 1 0 0 1 1 1 1 Ribosomal protein S11 ATP-synt_DE_N PF02823.16 CBZ29040.1 - 3.6e-13 49.2 0.0 7.7e-13 48.2 0.0 1.5 2 0 0 2 2 2 1 ATP synthase, Delta/Epsilon chain, beta-sandwich domain DUF773 PF05600.12 CBZ29041.1 - 5.2e-18 65.1 14.1 4.3e-10 38.9 4.5 3.5 1 1 2 3 3 3 3 CDK5 regulatory subunit-associated protein 3 Q_salvage PF10343.9 CBZ29041.1 - 0.0072 15.9 0.3 0.017 14.8 0.3 1.6 1 0 0 1 1 1 1 Potential Queuosine, Q, salvage protein family ABC_tran_CTD PF16326.5 CBZ29041.1 - 0.038 14.3 3.2 2.7 8.3 0.4 3.0 2 0 0 2 2 2 0 ABC transporter C-terminal domain SOAR PF16533.5 CBZ29041.1 - 0.053 13.5 4.7 0.089 12.8 1.0 2.6 2 0 0 2 2 2 0 STIM1 Orai1-activating region Prefoldin_2 PF01920.20 CBZ29041.1 - 0.072 13.0 4.1 5.7 6.9 0.5 2.5 2 0 0 2 2 2 0 Prefoldin subunit DUF2183 PF09949.9 CBZ29041.1 - 0.075 13.4 0.1 0.21 12.0 0.1 1.7 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2183) CENP-H PF05837.12 CBZ29041.1 - 0.12 12.8 8.2 2 8.8 0.5 2.9 3 0 0 3 3 3 0 Centromere protein H (CENP-H) Cytochrom_B562 PF07361.11 CBZ29041.1 - 0.12 13.0 3.0 0.19 12.4 0.8 2.2 2 0 0 2 2 2 0 Cytochrome b562 Phage_GPO PF05929.11 CBZ29041.1 - 0.49 10.0 7.3 0.66 9.5 2.8 2.2 2 0 0 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase TolA_bind_tri PF16331.5 CBZ29041.1 - 0.89 9.7 6.3 0.12 12.4 1.6 2.0 2 0 0 2 2 2 0 TolA binding protein trimerisation ATG16 PF08614.11 CBZ29041.1 - 1.1 9.4 10.2 0.32 11.2 3.1 2.4 2 1 0 2 2 2 0 Autophagy protein 16 (ATG16) APG6_N PF17675.1 CBZ29041.1 - 2 8.9 9.4 0.33 11.5 1.9 2.4 2 0 0 2 2 2 0 Apg6 coiled-coil region BRE1 PF08647.11 CBZ29041.1 - 4.2 7.5 10.4 6.6 6.9 4.2 2.4 2 0 0 2 2 2 0 BRE1 E3 ubiquitin ligase DUF724 PF05266.14 CBZ29041.1 - 4.6 7.0 8.9 2 8.2 1.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF724) Cyclin PF08613.11 CBZ29043.1 - 2.5e-21 76.7 0.1 4e-21 76.1 0.1 1.3 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 CBZ29043.1 - 2.2e-05 24.2 0.2 3.5e-05 23.6 0.2 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain LRR_9 PF14580.6 CBZ29044.1 - 5.5e-20 71.6 0.3 1.2e-14 54.2 0.0 2.4 1 1 1 2 2 2 2 Leucine-rich repeat LRR_4 PF12799.7 CBZ29044.1 - 4.7e-13 49.1 13.5 7e-05 23.1 0.0 4.1 3 1 0 4 4 4 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CBZ29044.1 - 1.2e-09 37.8 14.5 8.5e-05 22.2 4.9 3.6 1 1 1 3 3 3 3 Leucine rich repeat DpaA_N PF16924.5 CBZ29044.1 - 0.087 12.9 0.0 0.26 11.4 0.0 1.9 1 0 0 1 1 1 0 Dipicolinate synthase subunit A N-terminal domain LPD22 PF18834.1 CBZ29044.1 - 0.13 12.5 4.5 0.11 12.8 1.0 2.6 3 0 0 3 3 3 0 Large polyvalent protein associated domain 22 LRR_6 PF13516.6 CBZ29044.1 - 1.9 8.8 6.0 64 4.0 0.0 4.2 4 0 0 4 4 4 0 Leucine Rich repeat LRR_1 PF00560.33 CBZ29044.1 - 8.6 7.3 9.0 1.2e+02 3.9 1.0 4.6 3 2 1 4 4 4 0 Leucine Rich Repeat Ribosomal_L15e PF00827.17 CBZ29045.1 - 1.7e-85 285.6 7.4 2e-85 285.3 7.4 1.0 1 0 0 1 1 1 1 Ribosomal L15 ATP-synt_C PF00137.21 CBZ29046.1 - 2.4e-22 79.0 41.4 9e-12 45.2 12.6 3.1 3 0 0 3 3 3 2 ATP synthase subunit C SnoaL_2 PF12680.7 CBZ29047.1 - 1.5e-05 25.5 0.1 2.1e-05 25.1 0.1 1.5 1 1 0 1 1 1 1 SnoaL-like domain SnoaL_3 PF13474.6 CBZ29047.1 - 0.0008 19.7 0.2 0.0025 18.1 0.0 1.8 2 1 1 3 3 3 1 SnoaL-like domain SnoaL PF07366.12 CBZ29047.1 - 0.0035 17.1 0.0 0.0062 16.3 0.0 1.4 1 0 0 1 1 1 1 SnoaL-like polyketide cyclase DUF4440 PF14534.6 CBZ29047.1 - 0.015 15.7 0.0 0.04 14.3 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4440) OmpA PF00691.20 CBZ29048.1 - 0.16 12.4 0.1 0.16 12.4 0.1 2.6 2 1 1 3 3 3 0 OmpA family DUF3808 PF10300.9 CBZ29049.1 - 3.4e-26 92.0 4.2 1.9e-25 89.6 3.8 2.4 2 1 0 2 2 2 1 Protein of unknown function (DUF3808) TPR_12 PF13424.6 CBZ29049.1 - 2.5e-09 37.3 1.0 0.0005 20.3 0.1 3.5 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 CBZ29049.1 - 9.8e-08 31.6 4.2 0.15 12.2 0.0 5.1 6 0 0 6 6 6 2 Tetratricopeptide repeat ANAPC3 PF12895.7 CBZ29049.1 - 0.0002 21.5 3.1 0.2 11.9 0.6 4.1 4 0 0 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.6 CBZ29049.1 - 0.00071 20.0 1.8 4.5 7.8 0.3 4.8 4 2 1 5 5 5 2 Tetratricopeptide repeat TPR_1 PF00515.28 CBZ29049.1 - 0.00076 19.2 0.4 11 6.0 0.0 4.5 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_14 PF13428.6 CBZ29049.1 - 0.004 17.9 3.2 1.3 10.1 0.2 4.4 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_6 PF13174.6 CBZ29049.1 - 0.0074 16.9 3.0 7 7.5 0.4 4.4 4 0 0 4 4 4 1 Tetratricopeptide repeat DUF2225 PF09986.9 CBZ29049.1 - 0.18 11.5 4.7 0.36 10.5 0.4 3.0 2 1 1 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2225) TPR_16 PF13432.6 CBZ29049.1 - 0.56 10.9 6.7 0.48 11.1 0.5 3.4 4 1 0 4 4 4 0 Tetratricopeptide repeat HHV6-IE PF03753.13 CBZ29050.1 - 0.47 7.9 0.9 0.71 7.3 0.9 1.1 1 0 0 1 1 1 0 Human herpesvirus 6 immediate early protein CPSF_A PF03178.15 CBZ29051.1 - 9.7e-67 225.6 0.0 1.8e-66 224.6 0.0 1.4 1 0 0 1 1 1 1 CPSF A subunit region MMS1_N PF10433.9 CBZ29051.1 - 5.2e-08 32.0 0.0 9.5e-08 31.1 0.0 1.3 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term Ribosomal_60s PF00428.19 CBZ29052.1 - 2.9e-25 88.7 8.9 3.5e-25 88.4 8.9 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein DUF2275 PF10039.9 CBZ29052.1 - 0.035 14.2 0.3 0.043 13.9 0.3 1.1 1 0 0 1 1 1 0 Predicted integral membrane protein (DUF2275) Ribosomal_60s PF00428.19 CBZ29053.1 - 1.8e-25 89.3 9.8 2.1e-25 89.1 9.8 1.0 1 0 0 1 1 1 1 60s Acidic ribosomal protein Meth_synt_2 PF01717.18 CBZ29055.1 - 4.2e-155 515.9 0.0 2.4e-148 493.7 0.0 2.2 2 0 0 2 2 2 2 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.12 CBZ29055.1 - 3.5e-120 401.2 0.0 4.5e-110 368.0 0.0 3.0 3 0 0 3 3 3 3 Cobalamin-independent synthase, N-terminal domain MIP PF00230.20 CBZ29056.1 - 4.8e-47 160.6 12.6 6e-47 160.2 12.6 1.0 1 0 0 1 1 1 1 Major intrinsic protein RINGv PF12906.7 CBZ29057.1 - 1.4e-11 44.3 5.5 1.4e-11 44.3 5.5 1.9 2 0 0 2 2 2 1 RING-variant domain PhoLip_ATPase_C PF16212.5 CBZ29057.1 - 0.052 13.3 0.2 0.052 13.3 0.2 3.8 3 1 0 4 4 4 0 Phospholipid-translocating P-type ATPase C-terminal BT1 PF03092.16 CBZ29058.1 - 0.0063 14.8 23.2 0.0052 15.1 8.9 2.8 2 2 0 2 2 2 2 BT1 family MFS_2 PF13347.6 CBZ29058.1 - 0.1 11.2 27.6 0.043 12.4 15.6 2.9 1 1 0 2 2 2 0 MFS/sugar transport protein ERGIC_N PF13850.6 CBZ29058.1 - 0.41 11.0 2.9 13 6.2 0.1 3.4 3 0 0 3 3 3 0 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) DUF4131 PF13567.6 CBZ29058.1 - 6.8 6.3 13.2 8.3 6.0 0.1 3.7 3 1 0 3 3 3 0 Domain of unknown function (DUF4131) Pro_isomerase PF00160.21 CBZ29059.1 - 1.9e-44 151.7 0.0 2.4e-44 151.4 0.0 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD ResIII PF04851.15 CBZ29061.1 - 1.5e-15 57.6 0.0 4.1e-15 56.2 0.0 1.7 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit T5orf172 PF10544.9 CBZ29061.1 - 1.5e-08 35.1 0.0 3.7e-08 33.8 0.0 1.6 1 0 0 1 1 1 1 T5orf172 domain Helicase_C PF00271.31 CBZ29061.1 - 4.8e-08 33.3 0.0 1.5e-07 31.8 0.0 1.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 CBZ29061.1 - 2.6e-07 30.6 0.0 4.6e-07 29.8 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase SWI2_SNF2 PF18766.1 CBZ29061.1 - 0.029 14.0 0.0 0.058 13.1 0.0 1.4 1 0 0 1 1 1 0 SWI2/SNF2 ATPase BRCA-2_OB3 PF09104.10 CBZ29061.1 - 0.13 11.9 0.0 0.32 10.6 0.0 1.6 1 0 0 1 1 1 0 BRCA2, oligonucleotide/oligosaccharide-binding, domain 3 DUF3638 PF12340.8 CBZ29061.1 - 0.14 11.4 0.0 0.26 10.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3638) OrsD PF12013.8 CBZ29061.1 - 0.4 11.1 4.7 0.21 12.0 0.7 2.6 3 0 0 3 3 3 0 Orsellinic acid/F9775 biosynthesis cluster protein D zf-CCCH_4 PF18044.1 CBZ29062.1 - 7.9e-06 25.5 12.8 0.00017 21.3 5.4 2.4 2 0 0 2 2 2 2 CCCH-type zinc finger zf_CCCH_4 PF18345.1 CBZ29062.1 - 2.6e-05 24.1 7.2 0.00037 20.4 1.0 2.4 2 0 0 2 2 2 2 Zinc finger domain zf-CCCH PF00642.24 CBZ29062.1 - 4.2e-05 23.3 11.1 0.00094 19.0 3.9 2.4 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCHH PF10283.9 CBZ29062.1 - 0.41 10.7 3.8 4.3 7.4 0.1 2.4 2 0 0 2 2 2 0 PBZ domain zf-CCCH_2 PF14608.6 CBZ29062.1 - 0.7 10.4 7.8 2.5 8.7 2.3 2.7 2 1 0 2 2 2 0 RNA-binding, Nab2-type zinc finger MLIP PF15274.6 CBZ29063.1 - 0.036 14.0 0.1 0.057 13.3 0.1 1.2 1 0 0 1 1 1 0 Muscular LMNA-interacting protein Peptidase_C33 PF05412.12 CBZ29063.1 - 0.097 12.7 0.0 0.57 10.2 0.0 2.2 2 1 0 2 2 2 0 Equine arterivirus Nsp2-type cysteine proteinase Peptidase_M22 PF00814.25 CBZ29064.1 - 2e-86 290.1 0.0 2.8e-86 289.6 0.0 1.2 1 0 0 1 1 1 1 Glycoprotease family Carbam_trans_N PF02543.15 CBZ29064.1 - 0.12 12.0 0.0 0.99 9.0 0.0 2.0 2 0 0 2 2 2 0 Carbamoyltransferase N-terminus VCBS PF13517.6 CBZ29065.1 - 2.5e-13 50.4 17.4 0.0001 22.8 4.0 6.8 6 1 1 7 7 7 5 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FG-GAP PF01839.23 CBZ29065.1 - 0.0035 17.5 19.4 6.1 7.1 2.6 5.7 5 0 0 5 5 5 4 FG-GAP repeat BBS2_C PF14782.6 CBZ29065.1 - 0.019 13.8 0.1 5.6 5.6 0.0 3.0 3 0 0 3 3 3 0 Ciliary BBSome complex subunit 2, C-terminal BBS1 PF14779.6 CBZ29065.1 - 0.019 14.4 0.0 1.6 8.1 0.0 3.1 2 1 0 3 3 3 0 Ciliary BBSome complex subunit 1 Itfg2 PF15907.5 CBZ29065.1 - 0.14 11.2 0.7 26 3.7 0.0 3.5 3 1 1 4 4 4 0 Integrin-alpha FG-GAP repeat-containing protein 2 BBS2_Mid PF14783.6 CBZ29065.1 - 0.2 11.7 0.5 65 3.6 0.0 3.9 4 0 0 4 4 4 0 Ciliary BBSome complex subunit 2, middle region ZapB PF06005.12 CBZ29067.1 - 0.055 13.9 0.6 0.055 13.9 0.6 8.5 3 2 0 3 3 3 0 Cell division protein ZapB UCH PF00443.29 CBZ29068.1 - 2.6e-41 141.8 0.0 3.8e-41 141.3 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 CBZ29068.1 - 3e-11 43.5 0.2 3e-10 40.2 0.2 2.0 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase ubiquitin PF00240.23 CBZ29068.1 - 5.5e-09 35.7 0.0 1.7e-08 34.1 0.0 1.8 2 0 0 2 2 2 1 Ubiquitin family Ubiquitin_2 PF14560.6 CBZ29068.1 - 0.041 14.3 0.1 0.15 12.5 0.0 1.9 2 0 0 2 2 2 0 Ubiquitin-like domain Peptidase_C98 PF15499.6 CBZ29068.1 - 0.079 12.4 0.5 10 5.5 0.0 2.4 2 1 0 2 2 2 0 Ubiquitin-specific peptidase-like, SUMO isopeptidase UPF0262 PF06793.12 CBZ29069.1 - 0.075 13.1 0.0 0.13 12.3 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0262) RNA_pol_Rpb2_6 PF00562.28 CBZ29070.1 - 1.3e-120 403.0 0.0 1.7e-120 402.7 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 CBZ29070.1 - 1.3e-42 145.7 0.0 1.9e-42 145.1 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_7 PF04560.20 CBZ29070.1 - 2.6e-31 107.9 0.1 1.1e-30 105.8 0.2 2.0 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_2 PF04561.14 CBZ29070.1 - 6.9e-24 84.5 0.0 1.2e-23 83.8 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_4 PF04566.13 CBZ29070.1 - 7.6e-22 77.4 1.1 1.6e-21 76.3 1.1 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_3 PF04565.16 CBZ29070.1 - 2.5e-21 75.6 0.1 7.4e-21 74.1 0.1 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_5 PF04567.17 CBZ29070.1 - 6.3e-09 36.3 0.4 1.7e-08 34.9 0.4 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 OrfB_Zn_ribbon PF07282.11 CBZ29070.1 - 0.33 10.9 2.8 0.33 10.9 0.9 1.9 2 0 0 2 2 2 0 Putative transposase DNA-binding domain HisKA_2 PF07568.12 CBZ29071.1 - 0.098 12.8 0.0 0.26 11.4 0.0 1.7 1 0 0 1 1 1 0 Histidine kinase Trp_repressor PF01371.19 CBZ29072.1 - 0.12 12.6 0.0 0.56 10.4 0.0 2.0 2 0 0 2 2 2 0 Trp repressor protein Methyltr_RsmB-F PF01189.17 CBZ29073.1 - 5.7e-68 228.5 0.0 1e-67 227.7 0.0 1.4 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F Methyltr_RsmF_N PF17125.5 CBZ29073.1 - 4.5e-08 33.5 0.0 1.8e-07 31.6 0.0 2.0 2 0 0 2 2 2 1 N-terminal domain of 16S rRNA methyltransferase RsmF FtsJ PF01728.19 CBZ29073.1 - 6.9e-05 23.0 0.0 0.00024 21.3 0.0 1.9 2 0 0 2 2 2 1 FtsJ-like methyltransferase PCMT PF01135.19 CBZ29073.1 - 0.029 14.1 0.0 0.05 13.4 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) WD40 PF00400.32 CBZ29074.1 - 3.2e-13 49.9 12.4 0.014 16.2 0.1 7.4 7 0 0 7 7 7 4 WD domain, G-beta repeat NLE PF08154.12 CBZ29074.1 - 7.5e-11 42.4 0.5 1.4e-10 41.6 0.5 1.4 1 0 0 1 1 1 1 NLE (NUC135) domain ANAPC4_WD40 PF12894.7 CBZ29074.1 - 9.1e-05 22.7 0.2 2.3 8.6 0.0 4.4 3 1 1 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain Lactonase PF10282.9 CBZ29074.1 - 0.045 13.0 0.0 0.089 12.0 0.0 1.4 1 0 0 1 1 1 0 Lactonase, 7-bladed beta-propeller CLP1_P PF16575.5 CBZ29075.1 - 1.7e-09 37.8 0.0 6.7e-09 35.8 0.0 1.9 3 0 0 3 3 3 1 mRNA cleavage and polyadenylation factor CLP1 P-loop CLP1_N PF16573.5 CBZ29075.1 - 6.6e-09 35.9 0.0 1.4e-08 34.8 0.0 1.6 1 0 0 1 1 1 1 N-terminal beta-sandwich domain of polyadenylation factor Clp1 PF06807.14 CBZ29075.1 - 4.4e-05 23.9 0.0 8.9e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 Pre-mRNA cleavage complex II protein Clp1 SDA1 PF05285.12 CBZ29076.1 - 0.0042 16.5 16.4 0.0048 16.4 16.4 1.2 1 0 0 1 1 1 1 SDA1 BUD22 PF09073.10 CBZ29076.1 - 0.0048 16.3 11.0 0.0045 16.4 11.0 1.2 1 0 0 1 1 1 1 BUD22 DUF4746 PF15928.5 CBZ29076.1 - 0.12 11.8 9.2 0.15 11.4 9.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Cnd2 PF05786.14 CBZ29076.1 - 0.15 10.7 8.0 0.19 10.4 8.0 1.2 1 0 0 1 1 1 0 Condensin complex subunit 2 Nop14 PF04147.12 CBZ29076.1 - 0.16 10.2 18.3 0.17 10.0 18.3 1.1 1 0 0 1 1 1 0 Nop14-like family Nop16 PF09420.10 CBZ29076.1 - 0.37 10.8 4.8 0.45 10.5 4.8 1.1 1 0 0 1 1 1 0 Ribosome biogenesis protein Nop16 CNDH2_C PF16858.5 CBZ29076.1 - 1.3 8.8 7.5 1.6 8.6 7.5 1.3 1 0 0 1 1 1 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term TFIIF_alpha PF05793.12 CBZ29076.1 - 1.8 7.1 16.1 2.2 6.8 16.1 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) DUF2722 PF10846.8 CBZ29076.1 - 2.3 7.1 6.1 2.7 6.8 6.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) CDC45 PF02724.14 CBZ29076.1 - 2.7 6.2 11.8 3.5 5.8 11.8 1.2 1 0 0 1 1 1 0 CDC45-like protein RRN3 PF05327.11 CBZ29076.1 - 7.9 4.9 12.0 9.4 4.6 12.0 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 NOA36 PF06524.12 CBZ29076.1 - 8.2 5.7 27.7 11 5.2 27.7 1.1 1 0 0 1 1 1 0 NOA36 protein SAPS PF04499.15 CBZ29076.1 - 8.8 5.0 7.5 9.9 4.8 7.5 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein CLP1_P PF16575.5 CBZ29077.1 - 1.7e-09 37.7 0.0 6.7e-09 35.8 0.0 1.9 3 0 0 3 3 3 1 mRNA cleavage and polyadenylation factor CLP1 P-loop CLP1_N PF16573.5 CBZ29077.1 - 6.9e-09 35.8 0.0 1.4e-08 34.8 0.0 1.5 1 0 0 1 1 1 1 N-terminal beta-sandwich domain of polyadenylation factor Clp1 PF06807.14 CBZ29077.1 - 4.4e-05 23.9 0.0 8.9e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 Pre-mRNA cleavage complex II protein Clp1 SDA1 PF05285.12 CBZ29078.1 - 0.0022 17.5 15.4 0.0026 17.3 15.4 1.2 1 0 0 1 1 1 1 SDA1 BUD22 PF09073.10 CBZ29078.1 - 0.0039 16.6 11.5 0.0038 16.6 11.5 1.2 1 0 0 1 1 1 1 BUD22 DUF4746 PF15928.5 CBZ29078.1 - 0.062 12.7 8.3 0.082 12.3 8.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Nop14 PF04147.12 CBZ29078.1 - 0.15 10.2 18.7 0.17 10.1 18.7 1.1 1 0 0 1 1 1 0 Nop14-like family Nop16 PF09420.10 CBZ29078.1 - 0.5 10.4 4.8 0.64 10.0 4.8 1.1 1 0 0 1 1 1 0 Ribosome biogenesis protein Nop16 TFIIF_alpha PF05793.12 CBZ29078.1 - 1.6 7.3 15.7 1.9 7.0 15.7 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) CDC45 PF02724.14 CBZ29078.1 - 1.8 6.8 10.9 2.4 6.3 10.9 1.3 1 0 0 1 1 1 0 CDC45-like protein Cwf_Cwc_15 PF04889.12 CBZ29078.1 - 1.9 8.1 24.2 2.7 7.6 24.2 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein NOA36 PF06524.12 CBZ29078.1 - 3.8 6.7 26.4 5.2 6.3 26.4 1.1 1 0 0 1 1 1 0 NOA36 protein PPP4R2 PF09184.11 CBZ29078.1 - 8.6 5.9 24.8 12 5.4 24.8 1.2 1 0 0 1 1 1 0 PPP4R2 Fez1 PF06818.15 CBZ29079.1 - 0.73 10.3 124.5 1.5 9.2 9.9 6.3 2 2 4 6 6 6 0 Fez1 Cupin_4 PF08007.12 CBZ29080.1 - 2.1e-40 139.1 0.5 1.5e-39 136.3 0.5 2.0 1 1 0 1 1 1 1 Cupin superfamily protein Cupin_8 PF13621.6 CBZ29080.1 - 9.7e-07 28.8 0.0 8.3e-06 25.7 0.0 2.1 1 1 0 1 1 1 1 Cupin-like domain Cupin_2 PF07883.11 CBZ29080.1 - 0.061 13.0 0.0 0.18 11.5 0.0 1.7 1 0 0 1 1 1 0 Cupin domain Helicase_C PF00271.31 CBZ29081.1 - 2.5e-10 40.7 0.0 6.4e-10 39.4 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 CBZ29081.1 - 3.9e-06 26.8 0.0 8.9e-06 25.6 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Phage_portal_2 PF05136.13 CBZ29081.1 - 0.031 13.4 1.4 0.061 12.5 1.4 1.4 1 1 0 1 1 1 0 Phage portal protein, lambda family HA2 PF04408.23 CBZ29081.1 - 0.54 10.6 0.0 0.54 10.6 0.0 2.8 3 1 0 3 3 3 0 Helicase associated domain (HA2) 2OG-FeII_Oxy_3 PF13640.6 CBZ29084.1 - 2.4e-05 25.1 0.1 5.3e-05 24.0 0.1 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.6 CBZ29084.1 - 0.0075 16.9 0.0 0.015 16.0 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily COPIIcoated_ERV PF07970.12 CBZ29085.1 - 1.2e-19 71.0 0.0 2e-19 70.3 0.0 1.3 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.6 CBZ29085.1 - 1.2e-07 31.9 0.0 2.5e-07 31.0 0.0 1.5 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) Kinesin PF00225.23 CBZ29086.1 - 8.6e-89 297.7 0.4 1.8e-88 296.7 0.0 1.6 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 CBZ29086.1 - 1.7e-15 57.2 0.0 3.4e-15 56.3 0.0 1.5 1 0 0 1 1 1 1 Microtubule binding Tombus_P33 PF08500.10 CBZ29086.1 - 0.062 13.3 0.1 0.16 12.0 0.1 1.6 1 0 0 1 1 1 0 Tombusvirus p33 DUF3972 PF13118.6 CBZ29086.1 - 0.099 13.1 0.2 0.21 12.0 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3972) KinB_sensor PF16767.5 CBZ29086.1 - 0.19 12.2 3.4 0.37 11.3 3.4 1.4 1 0 0 1 1 1 0 Sensor domain of alginate biosynthesis sensor protein KinB TMF_DNA_bd PF12329.8 CBZ29086.1 - 3.9 7.6 10.3 0.18 11.8 3.5 2.2 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding CRAL_TRIO PF00650.20 CBZ29087.1 - 1.4e-13 50.9 0.1 4.2e-13 49.3 0.0 1.8 2 0 0 2 2 2 1 CRAL/TRIO domain BatA PF07584.11 CBZ29087.1 - 0.77 10.2 4.9 26 5.3 0.7 3.6 3 0 0 3 3 3 0 Aerotolerance regulator N-terminal CRAL_TRIO PF00650.20 CBZ29088.1 - 2e-13 50.4 0.0 3.1e-13 49.8 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain Aa_trans PF01490.18 CBZ29089.1 - 1.8e-29 102.7 16.8 2e-29 102.6 16.8 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Aa_trans PF01490.18 CBZ29090.1 - 6.1e-53 180.0 32.9 7.6e-53 179.7 32.9 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Aa_trans PF01490.18 CBZ29091.1 - 6.1e-53 180.0 32.9 7.6e-53 179.7 32.9 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Aa_trans PF01490.18 CBZ29092.1 - 1.2e-48 165.9 38.2 1.4e-48 165.6 38.2 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein AA_permease_2 PF13520.6 CBZ29092.1 - 1.3e-09 37.4 22.5 1.3e-09 37.4 22.5 2.0 2 0 0 2 2 2 1 Amino acid permease Trp_Tyr_perm PF03222.13 CBZ29092.1 - 2.7e-05 23.4 17.9 2.7e-05 23.4 17.9 2.1 2 1 0 2 2 2 1 Tryptophan/tyrosine permease family CRAL_TRIO PF00650.20 CBZ29093.1 - 4.3e-13 49.3 0.0 6.8e-13 48.6 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain Syd PF07348.12 CBZ29093.1 - 0.0079 15.9 0.0 0.016 14.9 0.0 1.5 1 0 0 1 1 1 1 Syd protein (SUKH-2) Peptidase_C2 PF00648.21 CBZ29096.1 - 4.3e-46 157.3 0.0 5.9e-46 156.8 0.0 1.2 1 0 0 1 1 1 1 Calpain family cysteine protease DUF1935 PF09149.10 CBZ29096.1 - 8.8e-26 90.3 0.1 1.6e-25 89.5 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1935) Peptidase_C2 PF00648.21 CBZ29097.1 - 5.7e-32 110.9 0.0 9.3e-32 110.2 0.0 1.3 1 0 0 1 1 1 1 Calpain family cysteine protease DUF1935 PF09149.10 CBZ29097.1 - 2e-15 57.0 0.0 4.9e-15 55.8 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1935) Peptidase_C2 PF00648.21 CBZ29098.1 - 2.4e-16 59.7 0.0 1e-15 57.6 0.0 1.9 1 1 0 1 1 1 1 Calpain family cysteine protease DUF1935 PF09149.10 CBZ29098.1 - 1e-15 58.0 0.0 1.8e-15 57.2 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1935) Amastin PF07344.11 CBZ29099.1 - 1.9e-51 174.0 10.9 2.2e-51 173.8 10.9 1.0 1 0 0 1 1 1 1 Amastin surface glycoprotein Amastin PF07344.11 CBZ29100.1 - 2.5e-50 170.4 9.0 2.9e-50 170.1 9.0 1.1 1 0 0 1 1 1 1 Amastin surface glycoprotein DUF4407 PF14362.6 CBZ29100.1 - 5.5 6.2 6.2 9.2 5.5 6.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Amastin PF07344.11 CBZ29101.1 - 2.2e-54 183.5 6.9 2.6e-54 183.3 6.9 1.1 1 0 0 1 1 1 1 Amastin surface glycoprotein DUF4525 PF15027.6 CBZ29101.1 - 0.24 11.1 0.5 2.5 7.8 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4525) DUF4407 PF14362.6 CBZ29101.1 - 0.45 9.8 4.0 0.75 9.1 4.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) SUR7 PF06687.12 CBZ29101.1 - 2.2 7.9 10.6 2.8 7.5 4.9 2.2 2 0 0 2 2 2 0 SUR7/PalI family CrgA PF06781.12 CBZ29101.1 - 3.2 7.9 9.8 0.084 12.9 1.9 2.4 2 0 0 2 2 2 0 Cell division protein CrgA Peptidase_C2 PF00648.21 CBZ29102.1 - 3.4e-64 216.7 0.0 4.5e-64 216.3 0.0 1.1 1 0 0 1 1 1 1 Calpain family cysteine protease DUF1935 PF09149.10 CBZ29102.1 - 2.6e-17 63.1 0.2 5.4e-17 62.1 0.2 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1935) Calpain_III PF01067.22 CBZ29102.1 - 0.012 15.9 0.0 0.031 14.6 0.0 1.7 1 0 0 1 1 1 0 Calpain large subunit, domain III AAA_16 PF13191.6 CBZ29103.1 - 0.0034 17.8 0.1 0.008 16.6 0.1 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_14 PF13173.6 CBZ29103.1 - 0.058 13.4 0.0 0.083 12.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain Sulfotransfer_4 PF17784.1 CBZ29104.1 - 6.6e-42 143.8 0.0 1.7e-41 142.4 0.0 1.6 1 1 0 1 1 1 1 Sulfotransferase domain cNMP_binding PF00027.29 CBZ29105.1 - 3.1e-23 81.6 0.8 3.2e-06 27.1 0.0 5.0 4 1 0 4 4 4 4 Cyclic nucleotide-binding domain DUF3606 PF12244.8 CBZ29105.1 - 0.29 11.1 1.9 9.6 6.2 0.0 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3606) DnaJ PF00226.31 CBZ29107.1 - 9.2e-23 80.2 0.5 1.7e-22 79.3 0.5 1.5 1 0 0 1 1 1 1 DnaJ domain DnaJ-X PF14308.6 CBZ29107.1 - 0.0064 16.0 0.4 0.012 15.1 0.4 1.3 1 0 0 1 1 1 1 X-domain of DnaJ-containing TRM13 PF05206.14 CBZ29108.1 - 3.7e-38 131.6 0.0 2.9e-26 92.6 0.0 3.1 1 1 1 2 2 2 2 Methyltransferase TRM13 zf-U11-48K PF05253.12 CBZ29108.1 - 4.5e-10 39.2 1.6 9.6e-10 38.2 1.6 1.6 1 0 0 1 1 1 1 U11-48K-like CHHC zinc finger zf-TRM13_CCCH PF11722.8 CBZ29108.1 - 4.7e-08 32.6 8.8 4.7e-08 32.6 8.8 2.2 2 0 0 2 2 2 1 CCCH zinc finger in TRM13 protein zf-ACC PF17848.1 CBZ29108.1 - 0.047 13.8 1.8 0.052 13.6 0.1 2.1 2 0 0 2 2 2 0 Acetyl-coA carboxylase zinc finger domain ABC_membrane_2 PF06472.15 CBZ29110.1 - 1.8e-75 253.8 4.3 1.8e-75 253.8 4.3 1.8 2 0 0 2 2 2 1 ABC transporter transmembrane region 2 ABC_tran PF00005.27 CBZ29110.1 - 7.2e-15 55.7 0.0 1.4e-14 54.8 0.0 1.5 1 0 0 1 1 1 1 ABC transporter GHMP_kinases_C PF08544.13 CBZ29112.1 - 5.6e-16 58.7 0.3 1.1e-15 57.8 0.3 1.5 1 0 0 1 1 1 1 GHMP kinases C terminal GHMP_kinases_N PF00288.26 CBZ29112.1 - 9.5e-13 48.2 0.4 2.3e-12 47.0 0.4 1.7 1 0 0 1 1 1 1 GHMP kinases N terminal domain YcaO PF02624.16 CBZ29112.1 - 0.028 13.7 0.0 0.089 12.1 0.0 1.7 1 1 0 1 1 1 0 YcaO cyclodehydratase, ATP-ad Mg2+-binding Aa_trans PF01490.18 CBZ29113.1 - 4.3e-48 164.0 34.6 5.2e-48 163.7 34.6 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 CBZ29113.1 - 1.6e-11 43.9 12.3 1.6e-11 43.9 12.3 2.2 1 1 0 2 2 2 1 Tryptophan/tyrosine permease family Aa_trans PF01490.18 CBZ29114.1 - 9.8e-48 162.9 32.3 1.3e-47 162.5 32.3 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 CBZ29114.1 - 1.7e-07 30.6 13.3 1.7e-07 30.6 13.3 2.2 1 1 0 2 2 2 1 Tryptophan/tyrosine permease family MaAIMP_sms PF16951.5 CBZ29114.1 - 0.1 12.3 0.3 0.1 12.3 0.3 2.5 2 0 0 2 2 2 0 Putative methionine and alanine importer, small subunit OppC_N PF12911.7 CBZ29114.1 - 1.9 8.6 6.9 3.4 7.7 0.3 3.5 3 0 0 3 3 3 0 N-terminal TM domain of oligopeptide transport permease C Aa_trans PF01490.18 CBZ29115.1 - 2e-42 145.4 32.1 2.7e-42 144.9 32.1 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein FA_hydroxylase PF04116.13 CBZ29116.1 - 1.6e-16 60.8 14.2 3e-16 60.0 14.2 1.4 1 0 0 1 1 1 1 Fatty acid hydroxylase superfamily DUF3323 PF11796.8 CBZ29117.1 - 0.016 15.1 3.0 0.03 14.2 3.0 1.3 1 0 0 1 1 1 0 Protein of unknown function N-terminus (DUF3323) UL42 PF17638.2 CBZ29117.1 - 0.35 10.8 5.8 0.93 9.5 5.8 1.7 1 0 0 1 1 1 0 HCMV UL42 FlgN PF05130.12 CBZ29117.1 - 5.3 7.5 7.9 4.1 7.9 2.1 2.2 2 0 0 2 2 2 0 FlgN protein Ribosomal_L7Ae PF01248.26 CBZ29118.1 - 0.0001 22.0 0.0 0.00027 20.6 0.0 1.7 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Histone_HNS PF00816.21 CBZ29118.1 - 0.014 16.2 0.4 0.055 14.3 0.1 2.2 2 0 0 2 2 2 0 H-NS histone family Antimicrobial19 PF08225.11 CBZ29118.1 - 0.031 13.9 0.1 0.068 12.8 0.1 1.5 1 0 0 1 1 1 0 Pseudin antimicrobial peptide DUF3391 PF11871.8 CBZ29118.1 - 0.078 13.5 0.1 0.078 13.5 0.1 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF3391) Tudor_1_RapA PF18339.1 CBZ29119.1 - 0.16 12.0 0.8 0.49 10.4 0.2 2.2 2 0 0 2 2 2 0 RapA N-terminal Tudor like domain 1 Secretin_N PF03958.17 CBZ29120.1 - 0.046 14.1 0.0 0.83 10.1 0.0 2.8 2 0 0 2 2 2 0 Bacterial type II/III secretion system short domain DUF2201_N PF13203.6 CBZ29120.1 - 0.06 12.9 9.1 0.47 10.0 3.0 2.9 2 1 1 3 3 3 0 Putative metallopeptidase domain WRNPLPNID PF15017.6 CBZ29120.1 - 0.17 12.8 0.1 0.71 10.8 0.1 2.0 1 0 0 1 1 1 0 Putative WW-binding domain and destruction box SMBP PF16785.5 CBZ29121.1 - 0.23 11.7 2.9 1.1 9.5 0.1 2.6 2 0 0 2 2 2 0 Small metal-binding protein FtsJ PF01728.19 CBZ29122.1 - 1.1e-42 146.1 0.0 1.4e-42 145.8 0.0 1.1 1 0 0 1 1 1 1 FtsJ-like methyltransferase C2 PF00168.30 CBZ29125.1 - 1.2e-21 76.9 0.0 1.7e-21 76.5 0.0 1.2 1 0 0 1 1 1 1 C2 domain DOCK-C2 PF14429.6 CBZ29125.1 - 0.041 13.7 0.0 0.076 12.8 0.0 1.4 1 0 0 1 1 1 0 C2 domain in Dock180 and Zizimin proteins CEP76-C2 PF15627.6 CBZ29125.1 - 0.11 12.1 0.0 0.19 11.3 0.0 1.3 1 0 0 1 1 1 0 CEP76 C2 domain cPLA2_C2 PF18695.1 CBZ29125.1 - 0.12 12.3 0.0 0.37 10.8 0.0 1.7 2 0 0 2 2 2 0 Cytosolic phospholipases A2 C2-domain Peptidase_M41 PF01434.18 CBZ29127.1 - 2.5e-45 154.7 0.0 5.8e-45 153.5 0.0 1.6 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.29 CBZ29127.1 - 6.5e-34 117.2 0.0 1.4e-33 116.1 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 CBZ29127.1 - 4.6e-10 39.1 0.1 1.2e-09 37.8 0.1 1.7 1 0 0 1 1 1 1 AAA+ lid domain AAA_22 PF13401.6 CBZ29127.1 - 0.0013 19.0 0.5 0.56 10.5 0.1 2.8 1 1 1 2 2 2 1 AAA domain AAA_5 PF07728.14 CBZ29127.1 - 0.0014 18.6 0.8 0.17 11.9 0.3 2.7 3 0 0 3 3 2 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 CBZ29127.1 - 0.0027 17.9 0.0 0.0068 16.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_18 PF13238.6 CBZ29127.1 - 0.0053 17.3 0.0 0.028 14.9 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 CBZ29127.1 - 0.009 16.4 0.3 0.03 14.7 0.3 2.1 1 1 0 1 1 1 1 AAA ATPase domain LRRC37 PF15779.5 CBZ29127.1 - 0.025 14.9 0.2 0.071 13.5 0.2 1.7 1 0 0 1 1 1 0 Leucine-rich repeat-containing protein 37 family RuvB_N PF05496.12 CBZ29127.1 - 0.031 14.0 0.0 0.074 12.8 0.0 1.6 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain IstB_IS21 PF01695.17 CBZ29127.1 - 0.05 13.3 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_28 PF13521.6 CBZ29127.1 - 0.1 12.9 0.0 0.35 11.1 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 CBZ29127.1 - 0.11 12.7 0.0 0.25 11.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 CBZ29127.1 - 0.12 11.8 0.3 0.24 10.8 0.3 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI MFS_1 PF07690.16 CBZ29129.1 - 5.8e-09 35.3 27.5 5.8e-09 35.3 27.5 3.9 2 2 1 3 3 3 2 Major Facilitator Superfamily Nodulin-like PF06813.13 CBZ29129.1 - 0.0071 15.9 8.3 0.0071 15.9 8.3 2.4 2 0 0 2 2 2 1 Nodulin-like DUF3147 PF11345.8 CBZ29129.1 - 0.19 12.1 7.7 4.1 7.8 0.5 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3147) CesT PF05932.13 CBZ29131.1 - 2.1e-17 63.4 0.2 3.7e-16 59.3 0.0 2.4 2 0 0 2 2 2 1 Tir chaperone protein (CesT) family DivIC PF04977.15 CBZ29131.1 - 0.016 14.9 1.3 0.03 14.1 1.3 1.4 1 0 0 1 1 1 0 Septum formation initiator DHR10 PF18595.1 CBZ29131.1 - 0.055 13.5 4.4 0.093 12.8 4.4 1.3 1 0 0 1 1 1 0 Designed helical repeat protein 10 domain ABC_tran_CTD PF16326.5 CBZ29131.1 - 0.12 12.6 1.5 0.24 11.6 1.5 1.4 1 0 0 1 1 1 0 ABC transporter C-terminal domain DUF2543 PF10820.8 CBZ29132.1 - 0.016 15.4 0.0 0.036 14.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2543) DUF2310 PF10071.9 CBZ29132.1 - 0.02 14.2 0.2 0.045 13.0 0.1 1.6 1 1 0 1 1 1 0 Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310) TMF_DNA_bd PF12329.8 CBZ29133.1 - 0.057 13.4 4.1 0.13 12.3 4.1 1.5 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding DUF16 PF01519.16 CBZ29133.1 - 0.071 13.6 3.2 0.13 12.8 0.9 2.3 2 0 0 2 2 2 0 Protein of unknown function DUF16 Cucumopine_C PF18631.1 CBZ29133.1 - 0.13 12.2 0.4 18 5.3 0.0 2.5 1 1 1 2 2 2 0 Cucumopine synthase C-terminal helical bundle domain KxDL PF10241.9 CBZ29133.1 - 0.35 11.2 10.8 4.6 7.6 4.9 2.5 2 0 0 2 2 2 0 Uncharacterized conserved protein HAUS6_N PF14661.6 CBZ29133.1 - 0.52 9.8 10.0 0.15 11.7 6.2 1.8 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 6 N-terminus DUF745 PF05335.13 CBZ29133.1 - 1.5 8.5 8.9 6.4 6.5 2.7 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF745) Seryl_tRNA_N PF02403.22 CBZ29133.1 - 1.5 9.0 8.1 0.95 9.7 4.1 2.4 2 1 1 3 3 3 0 Seryl-tRNA synthetase N-terminal domain DUF1664 PF07889.12 CBZ29133.1 - 1.6 8.8 5.4 2.6 8.1 3.0 2.4 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) PGBA_C PF15437.6 CBZ29134.1 - 0.00029 21.1 3.4 0.00029 21.1 3.4 1.8 2 0 0 2 2 2 1 Plasminogen-binding protein pgbA C-terminal FTCD_C PF04961.12 CBZ29134.1 - 0.035 13.9 2.7 0.079 12.7 2.7 1.6 1 0 0 1 1 1 0 Formiminotransferase-cyclodeaminase BLOC1_2 PF10046.9 CBZ29134.1 - 0.09 13.1 3.9 0.23 11.8 2.7 2.2 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Rap1a PF18602.1 CBZ29134.1 - 0.1 12.9 0.6 0.36 11.2 0.1 2.1 2 1 0 2 2 2 0 Rap1a immunity proteins TarH PF02203.15 CBZ29134.1 - 0.15 12.0 7.8 7 6.5 0.0 2.4 2 1 0 2 2 2 0 Tar ligand binding domain homologue CotJB PF12652.7 CBZ29134.1 - 0.31 11.3 3.3 13 6.1 0.5 3.5 2 2 1 3 3 3 0 CotJB protein RSS_P20 PF11757.8 CBZ29134.1 - 0.45 11.0 4.9 13 6.3 2.5 2.7 2 1 0 2 2 2 0 Suppressor of RNA silencing P21-like N-terminal domain CheZ PF04344.13 CBZ29134.1 - 0.55 10.1 7.1 1.6 8.6 0.0 2.5 1 1 2 3 3 3 0 Chemotaxis phosphatase, CheZ KapB PF08810.10 CBZ29134.1 - 0.7 10.1 7.5 0.21 11.8 0.5 3.0 1 1 2 3 3 3 0 Kinase associated protein B TMF_DNA_bd PF12329.8 CBZ29135.1 - 0.019 15.0 3.5 0.048 13.7 3.5 1.7 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding Cucumopine_C PF18631.1 CBZ29135.1 - 0.048 13.6 0.4 9.4 6.2 0.1 2.5 1 1 1 2 2 2 0 Cucumopine synthase C-terminal helical bundle domain KxDL PF10241.9 CBZ29135.1 - 0.099 12.9 10.6 2.5 8.5 4.9 2.4 2 0 0 2 2 2 0 Uncharacterized conserved protein DUF16 PF01519.16 CBZ29135.1 - 0.11 12.9 5.4 0.18 12.3 2.2 2.4 2 1 0 2 2 2 0 Protein of unknown function DUF16 HAUS6_N PF14661.6 CBZ29135.1 - 0.27 10.8 10.5 0.07 12.7 6.1 1.9 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 6 N-terminus DUF745 PF05335.13 CBZ29135.1 - 0.46 10.2 8.8 2.9 7.6 2.6 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF745) DUF1664 PF07889.12 CBZ29135.1 - 0.63 10.1 4.5 1.4 9.0 3.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Seryl_tRNA_N PF02403.22 CBZ29135.1 - 0.73 10.1 8.6 0.69 10.2 4.6 2.5 2 1 1 3 3 3 0 Seryl-tRNA synthetase N-terminal domain UPF0242 PF06785.11 CBZ29135.1 - 4.9 7.2 11.1 32 4.6 10.9 2.0 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus C2 PF00168.30 CBZ29136.1 - 9.7e-19 67.6 0.0 1.5e-18 67.0 0.0 1.3 1 0 0 1 1 1 1 C2 domain C2 PF00168.30 CBZ29137.1 - 1.4e-21 76.7 0.1 1.7e-21 76.4 0.1 1.1 1 0 0 1 1 1 1 C2 domain Drf_FH1 PF06346.12 CBZ29137.1 - 2.1 8.0 50.0 3.2 7.4 50.0 1.3 1 0 0 1 1 1 0 Formin Homology Region 1 FAD-SLDH PF12318.8 CBZ29139.1 - 0.0065 16.6 0.1 0.013 15.6 0.1 1.4 1 0 0 1 1 1 1 Membrane bound FAD containing D-sorbitol dehydrogenase PGBA_C PF15437.6 CBZ29142.1 - 0.00029 21.1 3.4 0.00029 21.1 3.4 1.7 2 0 0 2 2 1 1 Plasminogen-binding protein pgbA C-terminal TarH PF02203.15 CBZ29142.1 - 0.013 15.4 4.2 3.8 7.4 3.4 2.4 2 0 0 2 2 2 0 Tar ligand binding domain homologue FTCD_C PF04961.12 CBZ29142.1 - 0.034 13.9 2.7 0.079 12.7 2.7 1.6 1 0 0 1 1 1 0 Formiminotransferase-cyclodeaminase FUSC PF04632.12 CBZ29142.1 - 0.037 12.6 0.1 2.6 6.5 0.3 2.0 1 1 1 2 2 2 0 Fusaric acid resistance protein family BLOC1_2 PF10046.9 CBZ29142.1 - 0.086 13.1 3.9 0.23 11.8 2.7 2.2 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Rap1a PF18602.1 CBZ29142.1 - 0.095 13.0 0.2 0.36 11.2 0.1 2.1 2 0 0 2 2 2 0 Rap1a immunity proteins PhaP_Bmeg PF09602.10 CBZ29142.1 - 0.24 11.3 5.6 0.35 10.8 4.8 1.7 2 0 0 2 2 2 0 Polyhydroxyalkanoic acid inclusion protein (PhaP_Bmeg) CotJB PF12652.7 CBZ29142.1 - 0.34 11.1 3.4 13 6.1 0.4 3.5 2 2 2 4 4 4 0 CotJB protein CheZ PF04344.13 CBZ29142.1 - 0.47 10.3 7.4 1.8 8.5 0.0 2.4 1 1 1 2 2 2 0 Chemotaxis phosphatase, CheZ KapB PF08810.10 CBZ29142.1 - 0.79 9.9 7.5 0.21 11.7 0.5 2.9 1 1 1 2 2 2 0 Kinase associated protein B RSS_P20 PF11757.8 CBZ29142.1 - 2.1 8.8 7.5 14 6.2 2.5 2.9 3 1 0 3 3 3 0 Suppressor of RNA silencing P21-like N-terminal domain PHM7_cyt PF14703.6 CBZ29142.1 - 9.5 6.4 9.4 16 5.6 8.6 2.0 1 1 1 2 2 2 0 Cytosolic domain of 10TM putative phosphate transporter MPM1 PF17234.2 CBZ29143.1 - 0.18 12.1 5.5 0.32 11.2 5.5 1.4 1 0 0 1 1 1 0 Mitochondrial peculiar membrane protein 1 PGBA_C PF15437.6 CBZ29143.1 - 0.3 11.5 7.9 0.067 13.6 4.0 1.9 2 0 0 2 2 2 0 Plasminogen-binding protein pgbA C-terminal MitMem_reg PF13012.6 CBZ29143.1 - 0.31 11.5 3.3 11 6.5 0.1 2.5 1 1 1 2 2 2 0 Maintenance of mitochondrial structure and function Enkurin PF13864.6 CBZ29143.1 - 0.42 11.1 6.8 0.66 10.4 5.0 2.3 2 1 0 2 2 2 0 Calmodulin-binding Fib_alpha PF08702.10 CBZ29143.1 - 2.2 8.5 6.8 1.9 8.7 4.1 2.2 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family PHM7_cyt PF14703.6 CBZ29143.1 - 5.2 7.3 9.7 8.3 6.6 9.4 1.6 1 1 0 1 1 1 0 Cytosolic domain of 10TM putative phosphate transporter Ras PF00071.22 CBZ29144.1 - 2.7e-22 79.1 0.3 5e-18 65.2 0.0 2.6 2 1 0 2 2 2 2 Ras family Roc PF08477.13 CBZ29144.1 - 8.7e-15 55.0 0.0 1.4e-08 34.9 0.0 2.5 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CBZ29144.1 - 1.6e-07 30.9 0.0 2.2e-05 24.0 0.0 2.3 2 0 0 2 2 2 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 CBZ29144.1 - 2e-07 30.7 0.1 3.6e-07 29.9 0.1 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 CBZ29144.1 - 9.2e-05 22.5 0.0 0.00043 20.3 0.0 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 CBZ29144.1 - 0.00027 20.4 0.0 0.0014 18.0 0.0 1.9 2 0 0 2 2 2 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 CBZ29144.1 - 0.044 13.7 0.1 7.4 6.4 0.1 2.3 2 0 0 2 2 2 0 RsgA GTPase DLIC PF05783.11 CBZ29144.1 - 0.074 11.9 0.0 13 4.5 0.0 2.6 3 0 0 3 3 3 0 Dynein light intermediate chain (DLIC) NOG1 PF06858.14 CBZ29144.1 - 0.15 11.8 0.1 0.31 10.8 0.1 1.5 1 0 0 1 1 1 0 Nucleolar GTP-binding protein 1 (NOG1) Aa_trans PF01490.18 CBZ29145.1 - 5.9e-48 163.6 43.8 7e-48 163.3 43.8 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 CBZ29145.1 - 0.00026 20.2 34.1 0.00049 19.3 34.1 1.4 1 1 0 1 1 1 1 Tryptophan/tyrosine permease family Aa_trans PF01490.18 CBZ29146.1 - 6.4e-48 163.5 43.5 7.6e-48 163.2 43.5 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 CBZ29146.1 - 0.00015 20.9 33.8 0.00031 19.9 33.8 1.5 1 1 0 1 1 1 1 Tryptophan/tyrosine permease family KIAA1430 PF13879.6 CBZ29147.1 - 1.1e-17 64.6 3.2 1.1e-17 64.6 3.2 1.5 2 0 0 2 2 2 1 KIAA1430 homologue MRFAP1 PF15155.6 CBZ29147.1 - 0.17 12.4 5.6 0.16 12.5 2.6 2.3 1 1 1 2 2 2 0 MORF4 family-associated protein1 ABC_membrane_3 PF13748.6 CBZ29147.1 - 0.22 10.7 0.0 0.42 9.8 0.0 1.4 1 0 0 1 1 1 0 ABC transporter transmembrane region DUF2244 PF10003.9 CBZ29148.1 - 0.034 13.8 0.5 0.046 13.4 0.5 1.1 1 0 0 1 1 1 0 Integral membrane protein (DUF2244) Bax1-I PF01027.20 CBZ29148.1 - 0.042 13.7 0.5 0.047 13.5 0.5 1.0 1 0 0 1 1 1 0 Inhibitor of apoptosis-promoting Bax1 MSP1a PF11670.8 CBZ29148.1 - 0.052 12.8 0.6 0.053 12.8 0.6 1.2 1 0 0 1 1 1 0 Major surface protein 1a (MSP1a) DUF3852 PF12963.7 CBZ29148.1 - 0.052 13.9 1.2 0.14 12.5 0.0 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF3852) DUF2427 PF10348.9 CBZ29148.1 - 0.11 12.2 0.5 0.15 11.9 0.5 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF2427) NblA PF04485.12 CBZ29151.1 - 0.14 12.6 0.2 31 5.1 0.0 2.6 2 0 0 2 2 2 0 Phycobilisome degradation protein nblA RBR PF17208.3 CBZ29153.1 - 0.014 16.1 0.1 0.014 16.1 0.1 4.0 5 0 0 5 5 5 0 RNA binding Region YbbR PF07949.12 CBZ29153.1 - 0.11 12.8 0.0 0.32 11.4 0.0 1.8 1 0 0 1 1 1 0 YbbR-like protein DUF4217 PF13959.6 CBZ29155.1 - 0.0051 17.0 0.0 0.014 15.6 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) IMUP PF15761.5 CBZ29156.1 - 0.38 11.5 0.1 0.38 11.5 0.1 3.3 4 0 0 4 4 4 0 Immortalisation up-regulated protein RRM_1 PF00076.22 CBZ29157.1 - 1e-05 25.3 0.0 1.8e-05 24.4 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) YhfH PF14149.6 CBZ29157.1 - 0.041 13.9 1.5 0.34 10.9 0.1 2.4 2 0 0 2 2 2 0 YhfH-like protein RRM_1 PF00076.22 CBZ29158.1 - 5.2e-08 32.6 0.0 9.7e-08 31.7 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SET PF00856.28 CBZ29160.1 - 2.2e-07 31.4 0.0 4.2e-06 27.2 0.0 2.2 1 1 0 1 1 1 1 SET domain BPL_LplA_LipB PF03099.19 CBZ29161.1 - 4.3e-12 46.1 0.0 7.6e-12 45.3 0.0 1.4 1 1 0 1 1 1 1 Biotin/lipoate A/B protein ligase family Nup54 PF13874.6 CBZ29162.1 - 0.0076 16.4 1.9 0.0076 16.4 1.9 1.6 2 0 0 2 2 2 1 Nucleoporin complex subunit 54 Gp58 PF07902.11 CBZ29162.1 - 0.024 12.9 3.0 0.037 12.3 3.0 1.2 1 0 0 1 1 1 0 gp58-like protein DUF2664 PF10867.8 CBZ29162.1 - 0.12 12.8 0.5 0.24 11.9 0.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2664) Baculo_PEP_C PF04513.12 CBZ29162.1 - 0.19 11.8 0.2 0.32 11.0 0.2 1.3 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Exonuc_VII_L PF02601.15 CBZ29162.1 - 0.88 9.1 4.1 1.3 8.5 4.1 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit Apolipoprotein PF01442.18 CBZ29162.1 - 1.1 9.1 10.4 2.4 8.0 10.4 1.5 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain DUF641 PF04859.12 CBZ29162.1 - 1.3 9.3 3.9 2.5 8.4 3.8 1.5 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) FAM184 PF15665.5 CBZ29162.1 - 1.4 8.7 6.9 1.9 8.2 6.9 1.1 1 0 0 1 1 1 0 Family with sequence similarity 184, A and B CdvA PF18822.1 CBZ29162.1 - 1.4 8.8 6.0 20 5.0 5.8 2.1 1 1 0 1 1 1 0 CdvA-like coiled-coil domain TMPIT PF07851.13 CBZ29162.1 - 1.8 7.8 3.8 2.6 7.2 3.8 1.1 1 0 0 1 1 1 0 TMPIT-like protein OmpH PF03938.14 CBZ29162.1 - 2.6 8.4 8.2 0.31 11.4 1.1 2.0 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) CLZ PF16526.5 CBZ29162.1 - 3.1 8.2 4.6 4.5 7.7 2.0 2.1 2 0 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels DHR10 PF18595.1 CBZ29162.1 - 4.4 7.4 10.4 0.93 9.6 4.4 2.2 2 0 0 2 2 2 0 Designed helical repeat protein 10 domain FAM76 PF16046.5 CBZ29162.1 - 6.6 6.0 6.0 10 5.4 6.0 1.1 1 0 0 1 1 1 0 FAM76 protein DUF4498 PF14926.6 CBZ29164.1 - 1.4e-18 67.1 0.0 1.9e-11 43.8 0.0 3.9 3 1 0 3 3 3 2 Domain of unknown function (DUF4498) EMP24_GP25L PF01105.24 CBZ29165.1 - 1.1e-25 90.6 0.0 1.3e-25 90.4 0.0 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Gypsy PF07253.11 CBZ29165.1 - 0.0033 16.1 0.4 0.0044 15.6 0.4 1.1 1 0 0 1 1 1 1 Gypsy protein EMP24_GP25L PF01105.24 CBZ29166.1 - 1.7e-19 70.5 0.0 1.9e-19 70.3 0.0 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Peptidase_M20 PF01546.28 CBZ29167.1 - 2e-27 96.3 0.2 2.6e-27 95.9 0.2 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 CBZ29167.1 - 3.5e-08 33.3 0.0 7.4e-08 32.3 0.0 1.6 1 0 0 1 1 1 1 Peptidase dimerisation domain Hydrolase_4 PF12146.8 CBZ29168.1 - 2.2e-65 220.3 0.0 2.6e-65 220.0 0.0 1.0 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 CBZ29168.1 - 3.5e-12 46.5 0.0 2.6e-11 43.7 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 CBZ29168.1 - 8.6e-12 46.1 0.0 1.2e-11 45.7 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 CBZ29168.1 - 1.9e-09 37.4 0.1 3.2e-07 30.1 0.1 2.1 1 1 0 1 1 1 1 Prolyl oligopeptidase family Peptidase_S15 PF02129.18 CBZ29168.1 - 0.00014 21.6 0.0 0.019 14.5 0.0 2.1 2 0 0 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) DUF2920 PF11144.8 CBZ29168.1 - 0.00026 20.3 0.1 0.065 12.4 0.0 2.9 2 1 0 2 2 2 1 Protein of unknown function (DUF2920) DLH PF01738.18 CBZ29168.1 - 0.00073 19.1 0.1 0.16 11.5 0.0 2.3 2 1 0 2 2 2 1 Dienelactone hydrolase family FSH1 PF03959.13 CBZ29168.1 - 0.00087 19.0 0.0 0.0017 18.1 0.0 1.4 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Esterase PF00756.20 CBZ29168.1 - 0.0014 18.3 0.0 0.0018 18.0 0.0 1.2 1 0 0 1 1 1 1 Putative esterase PGAP1 PF07819.13 CBZ29168.1 - 0.0045 16.7 0.0 0.006 16.3 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein Thioesterase PF00975.20 CBZ29168.1 - 0.0078 16.3 0.0 0.012 15.8 0.0 1.3 1 0 0 1 1 1 1 Thioesterase domain Abhydrolase_3 PF07859.13 CBZ29168.1 - 0.032 14.1 0.0 0.079 12.8 0.0 1.8 1 1 0 1 1 1 0 alpha/beta hydrolase fold Ser_hydrolase PF06821.13 CBZ29168.1 - 0.043 13.7 0.0 2.6 7.9 0.0 2.2 1 1 0 2 2 2 0 Serine hydrolase AXE1 PF05448.12 CBZ29168.1 - 0.054 12.2 0.8 4.1 6.0 0.0 2.8 2 1 1 3 3 3 0 Acetyl xylan esterase (AXE1) Abhydrolase_5 PF12695.7 CBZ29168.1 - 0.2 11.4 0.0 1 9.1 0.0 2.0 3 0 0 3 3 3 0 Alpha/beta hydrolase family SR-25 PF10500.9 CBZ29169.1 - 0.18 11.4 4.1 0.45 10.1 4.1 1.7 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein LRR_4 PF12799.7 CBZ29170.1 - 4.6e-12 45.9 5.9 0.057 13.9 0.0 6.2 3 2 5 8 8 8 7 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CBZ29170.1 - 1.7e-06 27.6 3.3 0.68 9.7 0.0 4.7 4 1 0 4 4 4 3 Leucine rich repeat LRR_9 PF14580.6 CBZ29170.1 - 0.12 11.9 1.0 15 5.0 0.3 3.1 2 1 1 3 3 3 0 Leucine-rich repeat LRR_1 PF00560.33 CBZ29170.1 - 3.4 8.6 8.9 97 4.2 0.0 5.9 7 1 0 7 7 7 0 Leucine Rich Repeat Cyt-b5 PF00173.28 CBZ29171.1 - 1.4e-05 25.2 0.0 1.8e-05 24.8 0.0 1.3 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Cyt-b5 PF00173.28 CBZ29172.1 - 9.3e-07 28.9 0.0 1.2e-06 28.5 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain DUF4335 PF14233.6 CBZ29172.1 - 0.033 14.1 0.4 0.049 13.5 0.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4335) TPR_14 PF13428.6 CBZ29172.1 - 0.07 14.0 0.9 0.92 10.5 0.0 2.2 1 1 1 2 2 2 0 Tetratricopeptide repeat Cyt-b5 PF00173.28 CBZ29173.1 - 3.1e-05 24.0 0.0 4.7e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Cyt-b5 PF00173.28 CBZ29174.1 - 2.7e-09 37.0 0.0 3.4e-09 36.7 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Cyt-b5 PF00173.28 CBZ29175.1 - 6e-09 35.9 0.0 8.5e-09 35.4 0.0 1.3 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain DUF1456 PF07308.13 CBZ29175.1 - 0.12 12.7 0.0 0.21 12.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1456) DUF3638 PF12340.8 CBZ29176.1 - 5.1e-30 104.5 0.1 4.2e-29 101.5 0.1 2.2 1 1 0 1 1 1 1 Protein of unknown function (DUF3638) DUF3645 PF12359.8 CBZ29176.1 - 7.6e-16 57.2 0.5 2.7e-15 55.4 0.5 2.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3645) zf-RanBP PF00641.18 CBZ29176.1 - 1.2e-07 30.9 22.2 0.00014 21.1 4.7 3.5 3 0 0 3 3 3 3 Zn-finger in Ran binding protein and others Thioredoxin_8 PF13905.6 CBZ29176.1 - 5.6e-06 26.6 0.0 1.4e-05 25.3 0.0 1.7 1 0 0 1 1 1 1 Thioredoxin-like ubiquitin PF00240.23 CBZ29176.1 - 0.00016 21.3 0.0 0.00035 20.3 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family TMEM51 PF15345.6 CBZ29176.1 - 0.72 9.7 5.3 0.12 12.2 0.0 2.2 2 0 0 2 2 2 0 Transmembrane protein 51 Vps36-NZF-N PF16988.5 CBZ29176.1 - 9.5 5.7 15.3 2.4 7.6 3.0 3.6 2 1 1 3 3 3 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain H_PPase PF03030.16 CBZ29177.1 - 4.5e-237 788.8 32.9 6e-237 788.4 32.9 1.2 1 0 0 1 1 1 1 Inorganic H+ pyrophosphatase RP853 PF17542.2 CBZ29177.1 - 4.4 6.3 7.9 2.2 7.3 0.1 2.9 3 0 0 3 3 3 0 Uncharacterized RP853 LRR_6 PF13516.6 CBZ29178.1 - 0.013 15.5 3.6 8.9 6.7 0.0 4.3 4 0 0 4 4 4 0 Leucine Rich repeat GvpG PF05120.12 CBZ29178.1 - 0.14 12.2 0.1 0.35 10.9 0.1 1.7 1 0 0 1 1 1 0 Gas vesicle protein G LRR_1 PF00560.33 CBZ29178.1 - 1.3 9.9 6.5 4.9 8.1 0.0 4.4 3 1 0 3 3 3 0 Leucine Rich Repeat MLTR_LBD PF17765.1 CBZ29180.1 - 0.014 15.5 3.1 0.014 15.5 3.1 5.0 6 0 0 6 6 6 0 MmyB-like transcription regulator ligand binding domain MT PF12777.7 CBZ29181.1 - 3.5e-06 26.3 0.1 3.5e-06 26.3 0.1 2.2 2 0 0 2 2 2 1 Microtubule-binding stalk of dynein motor Ribonuc_2-5A PF06479.12 CBZ29181.1 - 0.0087 16.2 1.8 2.5 8.3 0.1 2.5 2 0 0 2 2 2 2 Ribonuclease 2-5A RasGAP_C PF03836.15 CBZ29181.1 - 0.059 13.5 3.7 4.5 7.4 0.0 3.2 3 0 0 3 3 3 0 RasGAP C-terminus Bacillus_HBL PF05791.11 CBZ29181.1 - 0.13 12.1 8.2 2.1 8.2 0.1 3.1 3 0 0 3 3 3 0 Bacillus haemolytic enterotoxin (HBL) ACT PF01842.25 CBZ29181.1 - 0.46 10.3 3.4 2.8 7.8 0.1 3.5 4 0 0 4 4 4 0 ACT domain DUF5053 PF16476.5 CBZ29181.1 - 0.51 10.0 2.5 2.8 7.7 0.0 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF5053) Spc7 PF08317.11 CBZ29181.1 - 4.9 5.9 21.8 0.68 8.7 2.8 3.4 3 0 0 3 3 3 0 Spc7 kinetochore protein DUF4407 PF14362.6 CBZ29181.1 - 6.5 6.0 21.6 0.24 10.7 0.3 3.2 3 1 0 3 3 3 0 Domain of unknown function (DUF4407) Fib_alpha PF08702.10 CBZ29181.1 - 7.7 6.7 10.8 17 5.5 0.2 4.2 4 1 0 4 4 4 0 Fibrinogen alpha/beta chain family ABC_membrane PF00664.23 CBZ29182.1 - 2.5e-50 171.6 30.1 6.6e-29 101.4 12.8 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 CBZ29182.1 - 1.3e-45 155.3 0.0 3.5e-23 82.6 0.0 2.5 2 0 0 2 2 2 2 ABC transporter AAA_29 PF13555.6 CBZ29182.1 - 2.8e-10 39.8 2.1 1.2e-05 25.0 0.1 3.2 3 0 0 3 3 3 2 P-loop containing region of AAA domain AAA_21 PF13304.6 CBZ29182.1 - 9.6e-10 38.7 0.1 0.0036 17.1 0.1 4.7 4 1 1 5 5 5 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 CBZ29182.1 - 2e-09 37.2 0.0 0.038 13.4 0.0 4.2 4 0 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 CBZ29182.1 - 1.2e-07 32.4 0.0 0.00016 22.2 0.0 2.3 2 0 0 2 2 2 2 AAA domain T2SSE PF00437.20 CBZ29182.1 - 3.5e-06 26.3 0.1 0.018 14.1 0.1 2.4 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_16 PF13191.6 CBZ29182.1 - 9.2e-06 26.1 2.5 0.0078 16.6 0.1 3.4 3 0 0 3 3 3 1 AAA ATPase domain FtsK_SpoIIIE PF01580.18 CBZ29182.1 - 1.4e-05 24.6 0.2 0.017 14.4 0.0 2.5 2 0 0 2 2 2 2 FtsK/SpoIIIE family MMR_HSR1 PF01926.23 CBZ29182.1 - 1.6e-05 25.0 0.2 0.17 12.0 0.0 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase Dynamin_N PF00350.23 CBZ29182.1 - 9e-05 22.6 0.4 0.018 15.1 0.0 2.4 2 0 0 2 2 2 1 Dynamin family RsgA_GTPase PF03193.16 CBZ29182.1 - 9e-05 22.4 0.2 0.0098 15.8 0.0 2.4 2 0 0 2 2 2 1 RsgA GTPase AAA_25 PF13481.6 CBZ29182.1 - 0.00014 21.5 0.4 0.023 14.3 0.0 2.7 2 0 0 2 2 2 1 AAA domain DUF87 PF01935.17 CBZ29182.1 - 0.00031 20.9 0.6 0.65 10.0 0.1 2.3 2 0 0 2 2 2 2 Helicase HerA, central domain AAA_30 PF13604.6 CBZ29182.1 - 0.00035 20.4 0.1 0.28 10.9 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 CBZ29182.1 - 0.00036 20.8 1.3 0.26 11.6 0.0 2.9 3 0 0 3 3 2 1 AAA domain NACHT PF05729.12 CBZ29182.1 - 0.00072 19.5 0.3 0.15 12.0 0.0 2.7 2 0 0 2 2 2 1 NACHT domain MeaB PF03308.16 CBZ29182.1 - 0.0016 17.5 0.8 0.93 8.4 0.0 2.3 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB ATP_bind_1 PF03029.17 CBZ29182.1 - 0.027 14.2 0.7 5.8 6.6 0.1 2.5 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein TrwB_AAD_bind PF10412.9 CBZ29182.1 - 0.032 13.1 0.7 0.77 8.6 0.1 2.2 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain AAA_24 PF13479.6 CBZ29182.1 - 0.034 13.9 0.1 1.5 8.5 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 CBZ29182.1 - 0.04 14.1 1.6 0.9 9.7 0.1 2.7 2 0 0 2 2 2 0 AAA domain Viral_helicase1 PF01443.18 CBZ29182.1 - 0.05 13.3 0.2 6 6.5 0.0 2.5 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase RNA_helicase PF00910.22 CBZ29182.1 - 0.069 13.5 0.1 2.7 8.4 0.0 2.9 3 0 0 3 3 2 0 RNA helicase AAA_18 PF13238.6 CBZ29182.1 - 0.11 13.1 0.2 6.7 7.3 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 CBZ29182.1 - 0.11 11.9 0.2 11 5.5 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_5 PF07728.14 CBZ29182.1 - 0.16 12.0 0.1 11 6.0 0.0 2.4 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) CAP_GLY PF01302.25 CBZ29182.1 - 0.17 11.9 0.7 0.45 10.6 0.7 1.7 1 0 0 1 1 1 0 CAP-Gly domain Adeno_IVa2 PF02456.15 CBZ29182.1 - 0.2 10.4 1.0 0.61 8.8 0.1 2.0 2 0 0 2 2 2 0 Adenovirus IVa2 protein LapA_dom PF06305.11 CBZ29182.1 - 0.22 11.4 8.4 2.5 8.0 0.0 4.1 3 0 0 3 3 3 0 Lipopolysaccharide assembly protein A domain cobW PF02492.19 CBZ29182.1 - 0.4 10.3 7.4 0.95 9.0 0.2 2.8 3 0 0 3 3 2 0 CobW/HypB/UreG, nucleotide-binding domain ABC_ATPase PF09818.9 CBZ29182.1 - 1.7 7.4 3.8 0.94 8.2 0.1 2.2 3 0 0 3 3 3 0 Predicted ATPase of the ABC class ABC_tran PF00005.27 CBZ29183.1 - 3e-46 157.4 0.0 3.2e-23 82.8 0.0 2.9 3 0 0 3 3 3 2 ABC transporter ABC_membrane PF00664.23 CBZ29183.1 - 4.8e-46 157.6 20.1 1.3e-27 97.1 9.3 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region AAA_29 PF13555.6 CBZ29183.1 - 2.5e-10 40.0 0.2 1.2e-05 24.9 0.1 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_21 PF13304.6 CBZ29183.1 - 1.8e-09 37.9 0.0 0.0036 17.2 0.2 4.6 4 1 1 5 5 5 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 CBZ29183.1 - 1.8e-09 37.3 0.0 0.039 13.4 0.0 4.1 4 0 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 CBZ29183.1 - 1.3e-07 32.4 0.0 0.00018 22.1 0.0 2.3 2 0 0 2 2 2 2 AAA domain T2SSE PF00437.20 CBZ29183.1 - 7.8e-07 28.4 0.1 0.017 14.2 0.0 3.1 3 0 0 3 3 3 2 Type II/IV secretion system protein AAA_16 PF13191.6 CBZ29183.1 - 4.7e-06 27.1 0.7 0.0044 17.4 0.1 2.8 2 0 0 2 2 2 1 AAA ATPase domain FtsK_SpoIIIE PF01580.18 CBZ29183.1 - 1.5e-05 24.5 0.3 0.017 14.5 0.1 2.4 2 0 0 2 2 2 2 FtsK/SpoIIIE family MMR_HSR1 PF01926.23 CBZ29183.1 - 1.9e-05 24.7 0.2 0.21 11.7 0.0 2.5 2 0 0 2 2 2 2 50S ribosome-binding GTPase Dynamin_N PF00350.23 CBZ29183.1 - 7e-05 22.9 0.5 0.016 15.3 0.0 2.5 2 0 0 2 2 2 1 Dynamin family RsgA_GTPase PF03193.16 CBZ29183.1 - 0.0001 22.2 0.1 0.012 15.5 0.0 2.4 2 0 0 2 2 2 1 RsgA GTPase AAA_25 PF13481.6 CBZ29183.1 - 0.00011 21.9 0.4 0.019 14.5 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 CBZ29183.1 - 0.00026 21.3 1.2 0.23 11.7 0.0 2.9 3 0 0 3 3 2 1 AAA domain AAA_30 PF13604.6 CBZ29183.1 - 0.00028 20.7 0.1 0.23 11.1 0.0 2.8 2 0 0 2 2 2 1 AAA domain DUF87 PF01935.17 CBZ29183.1 - 0.00035 20.8 0.8 0.6 10.2 0.1 2.3 2 0 0 2 2 2 2 Helicase HerA, central domain MeaB PF03308.16 CBZ29183.1 - 0.00066 18.7 0.6 0.56 9.1 0.0 2.3 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB NACHT PF05729.12 CBZ29183.1 - 0.00085 19.3 0.4 0.14 12.1 0.0 2.4 2 0 0 2 2 2 1 NACHT domain ATP_bind_1 PF03029.17 CBZ29183.1 - 0.022 14.6 0.7 5.3 6.7 0.1 2.5 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein TrwB_AAD_bind PF10412.9 CBZ29183.1 - 0.023 13.6 0.6 0.7 8.7 0.1 2.2 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain cobW PF02492.19 CBZ29183.1 - 0.023 14.3 3.4 0.87 9.1 0.2 2.7 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_24 PF13479.6 CBZ29183.1 - 0.031 14.0 0.1 1.3 8.7 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 CBZ29183.1 - 0.034 14.3 1.6 0.83 9.8 0.1 2.7 2 0 0 2 2 2 0 AAA domain Viral_helicase1 PF01443.18 CBZ29183.1 - 0.049 13.4 0.2 5.5 6.7 0.0 2.4 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase RNA_helicase PF00910.22 CBZ29183.1 - 0.062 13.7 0.1 2.4 8.6 0.0 2.8 3 0 0 3 3 2 0 RNA helicase AAA_18 PF13238.6 CBZ29183.1 - 0.088 13.3 0.2 6.2 7.4 0.0 2.7 3 0 0 3 3 2 0 AAA domain AAA_5 PF07728.14 CBZ29183.1 - 0.12 12.3 0.1 10 6.1 0.0 2.5 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) CAP_GLY PF01302.25 CBZ29183.1 - 0.16 12.0 0.7 0.41 10.7 0.7 1.7 1 0 0 1 1 1 0 CAP-Gly domain Adeno_IVa2 PF02456.15 CBZ29183.1 - 0.17 10.6 0.8 0.55 9.0 0.1 1.9 2 0 0 2 2 2 0 Adenovirus IVa2 protein AAA_7 PF12775.7 CBZ29183.1 - 0.19 11.3 0.1 19 4.7 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region MobB PF03205.14 CBZ29183.1 - 0.22 11.4 0.2 18 5.2 0.1 2.5 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_19 PF13245.6 CBZ29183.1 - 0.31 11.4 0.9 15 5.9 0.1 3.2 3 0 0 3 3 3 0 AAA domain Roc PF08477.13 CBZ29183.1 - 0.82 9.9 1.9 31 4.8 0.3 2.5 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase CbiQ PF02361.16 CBZ29183.1 - 8.6 5.9 15.0 0.038 13.6 3.4 2.8 2 1 1 3 3 3 0 Cobalt transport protein ABC_tran PF00005.27 CBZ29184.1 - 6.3e-46 156.3 0.0 3.2e-23 82.8 0.0 2.4 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 CBZ29184.1 - 1.3e-38 133.3 25.8 1.7e-23 83.7 10.9 2.3 2 0 0 2 2 2 2 ABC transporter transmembrane region AAA_29 PF13555.6 CBZ29184.1 - 2.5e-10 39.9 0.2 1.2e-05 24.9 0.1 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_21 PF13304.6 CBZ29184.1 - 1.4e-09 38.2 0.0 0.0036 17.1 0.2 4.6 4 1 1 5 5 5 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 CBZ29184.1 - 1.9e-09 37.3 0.0 0.04 13.4 0.0 4.1 4 0 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 CBZ29184.1 - 1.2e-07 32.5 0.0 0.00018 22.1 0.0 2.3 2 0 0 2 2 2 2 AAA domain T2SSE PF00437.20 CBZ29184.1 - 3.6e-06 26.3 0.0 0.016 14.3 0.0 2.3 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_16 PF13191.6 CBZ29184.1 - 4.7e-06 27.1 0.7 0.0046 17.4 0.1 2.9 2 0 0 2 2 2 1 AAA ATPase domain FtsK_SpoIIIE PF01580.18 CBZ29184.1 - 1.5e-05 24.4 0.3 0.017 14.5 0.1 2.4 2 0 0 2 2 2 2 FtsK/SpoIIIE family MMR_HSR1 PF01926.23 CBZ29184.1 - 1.8e-05 24.8 0.2 0.21 11.7 0.0 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase Dynamin_N PF00350.23 CBZ29184.1 - 7.5e-05 22.8 0.5 0.016 15.3 0.0 2.4 2 0 0 2 2 2 1 Dynamin family AAA_25 PF13481.6 CBZ29184.1 - 0.00011 21.9 0.4 0.02 14.5 0.0 2.7 2 0 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 CBZ29184.1 - 0.00011 22.1 0.1 0.012 15.5 0.0 2.3 2 0 0 2 2 2 1 RsgA GTPase AAA_22 PF13401.6 CBZ29184.1 - 0.00024 21.4 1.2 0.24 11.7 0.0 3.0 3 0 0 3 3 2 1 AAA domain AAA_30 PF13604.6 CBZ29184.1 - 0.00034 20.4 0.1 0.24 11.1 0.0 2.6 2 0 0 2 2 2 1 AAA domain DUF87 PF01935.17 CBZ29184.1 - 0.00037 20.7 0.8 0.6 10.1 0.1 2.2 2 0 0 2 2 2 2 Helicase HerA, central domain NACHT PF05729.12 CBZ29184.1 - 0.00068 19.6 0.4 0.14 12.1 0.0 2.7 2 0 0 2 2 2 1 NACHT domain MeaB PF03308.16 CBZ29184.1 - 0.0007 18.7 0.6 0.59 9.1 0.0 2.3 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB TrwB_AAD_bind PF10412.9 CBZ29184.1 - 0.025 13.5 0.6 0.7 8.7 0.1 2.2 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain ATP_bind_1 PF03029.17 CBZ29184.1 - 0.026 14.3 0.7 5.4 6.7 0.1 2.4 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_33 PF13671.6 CBZ29184.1 - 0.027 14.6 1.6 0.83 9.8 0.1 2.9 2 0 0 2 2 2 0 AAA domain cobW PF02492.19 CBZ29184.1 - 0.03 13.9 3.4 0.88 9.1 0.2 2.5 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_24 PF13479.6 CBZ29184.1 - 0.031 14.0 0.1 1.4 8.6 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 CBZ29184.1 - 0.042 14.4 0.3 6.3 7.4 0.0 3.2 3 0 0 3 3 3 0 AAA domain Viral_helicase1 PF01443.18 CBZ29184.1 - 0.047 13.4 0.2 5.6 6.6 0.0 2.4 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase RNA_helicase PF00910.22 CBZ29184.1 - 0.065 13.6 0.1 2.5 8.6 0.0 2.8 3 0 0 3 3 2 0 RNA helicase AAA_5 PF07728.14 CBZ29184.1 - 0.11 12.5 0.1 11 6.1 0.0 2.6 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Adeno_IVa2 PF02456.15 CBZ29184.1 - 0.15 10.8 0.8 0.55 9.0 0.1 2.0 2 0 0 2 2 2 0 Adenovirus IVa2 protein CAP_GLY PF01302.25 CBZ29184.1 - 0.19 11.8 1.5 0.42 10.7 0.7 2.0 2 0 0 2 2 1 0 CAP-Gly domain AAA_7 PF12775.7 CBZ29184.1 - 0.2 11.2 0.1 19 4.7 0.0 2.2 2 0 0 2 2 2 0 P-loop containing dynein motor region MobB PF03205.14 CBZ29184.1 - 0.22 11.4 0.2 18 5.2 0.1 2.5 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B Roc PF08477.13 CBZ29184.1 - 0.82 9.9 1.9 31 4.8 0.3 2.5 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase ABC_ATPase PF09818.9 CBZ29184.1 - 1.2 7.9 3.3 0.91 8.2 0.1 2.2 3 0 0 3 3 3 0 Predicted ATPase of the ABC class PP2C PF00481.21 CBZ29187.1 - 2e-32 112.8 0.0 1.1e-27 97.3 0.0 2.4 2 0 0 2 2 2 2 Protein phosphatase 2C zf-UBP PF02148.19 CBZ29187.1 - 0.045 14.1 10.2 0.12 12.7 10.2 1.8 1 0 0 1 1 1 0 Zn-finger in ubiquitin-hydrolases and other protein zf-UBP_var PF17807.1 CBZ29187.1 - 0.12 12.1 2.8 0.28 11.0 2.8 1.5 1 0 0 1 1 1 0 Variant UBP zinc finger CSD PF00313.22 CBZ29188.1 - 3.1e-07 30.2 0.1 0.00016 21.5 0.1 2.5 2 0 0 2 2 2 2 'Cold-shock' DNA-binding domain CSD PF00313.22 CBZ29189.1 - 2.9e-11 43.1 0.0 4.9e-08 32.7 0.0 2.6 3 0 0 3 3 3 2 'Cold-shock' DNA-binding domain CSD PF00313.22 CBZ29190.1 - 0.0014 18.4 0.1 2.8 7.9 0.1 2.5 2 0 0 2 2 2 2 'Cold-shock' DNA-binding domain RE_XamI PF09572.10 CBZ29191.1 - 0.016 14.9 1.9 0.7 9.5 0.0 2.7 2 1 1 3 3 3 0 XamI restriction endonuclease HALZ PF02183.18 CBZ29191.1 - 9.2 6.6 12.4 2.4 8.4 1.4 4.5 4 1 1 5 5 5 0 Homeobox associated leucine zipper SPRY PF00622.28 CBZ29192.1 - 4.3e-06 26.8 0.0 1.2e-05 25.5 0.0 1.7 1 1 0 1 1 1 1 SPRY domain Neuralized PF07177.12 CBZ29192.1 - 0.13 12.3 0.0 0.32 11.0 0.0 1.7 1 0 0 1 1 1 0 Neuralized HMMR_N PF15905.5 CBZ29192.1 - 0.14 11.6 62.3 0.046 13.2 11.0 4.4 3 1 1 4 4 4 0 Hyaluronan mediated motility receptor N-terminal HHA PF05321.11 CBZ29193.1 - 0.13 12.6 1.3 1 9.7 0.2 3.0 2 0 0 2 2 2 0 Haemolysin expression modulating protein zf-LSD1 PF06943.12 CBZ29195.1 - 2e-10 40.3 7.0 2e-10 40.3 7.0 2.4 2 0 0 2 2 2 1 LSD1 zinc finger zinc-ribbons_6 PF07191.12 CBZ29195.1 - 0.082 12.9 10.6 0.71 9.9 7.3 2.2 2 0 0 2 2 2 0 zinc-ribbons DZR PF12773.7 CBZ29195.1 - 0.11 12.5 15.2 7 6.8 11.0 2.4 1 1 1 2 2 2 0 Double zinc ribbon Tmemb_55A PF09788.9 CBZ29195.1 - 0.34 10.0 12.9 4 6.4 13.1 2.0 1 1 0 1 1 1 0 Transmembrane protein 55A zinc_ribbon_4 PF13717.6 CBZ29195.1 - 1 9.3 0.0 1 9.3 0.0 4.0 3 1 1 4 4 3 0 zinc-ribbon domain HypA PF01155.19 CBZ29195.1 - 7.2 6.7 11.6 2 8.4 0.8 2.2 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA OrfB_Zn_ribbon PF07282.11 CBZ29195.1 - 7.9 6.5 10.9 3.8 7.5 2.4 2.7 1 1 2 3 3 3 0 Putative transposase DNA-binding domain SUIM_assoc PF16619.5 CBZ29196.1 - 1 9.4 11.4 0.72 10.0 8.7 2.1 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 DGF-1_C PF11040.8 CBZ29196.1 - 1.4 9.0 7.6 8.5 6.5 0.0 4.1 4 0 0 4 4 4 0 Dispersed gene family protein 1 of Trypanosoma cruzi C-terminus TFIIA PF03153.13 CBZ29196.1 - 2.2 8.2 8.9 0.34 10.8 0.8 2.9 3 0 0 3 3 3 0 Transcription factor IIA, alpha/beta subunit RcsF PF16358.5 CBZ29197.1 - 0.044 13.8 0.1 0.16 12.1 0.1 2.0 1 0 0 1 1 1 0 RcsF lipoprotein IL3Ra_N PF18611.1 CBZ29197.1 - 0.18 11.8 0.0 0.38 10.8 0.0 1.5 1 0 0 1 1 1 0 IL-3 receptor alpha chain N-terminal domain ABC_tran PF00005.27 CBZ29199.1 - 8e-41 139.8 0.0 1.4e-24 87.2 0.0 2.7 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 CBZ29199.1 - 1.1e-39 136.8 19.0 5.9e-20 72.0 2.7 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.19 CBZ29199.1 - 6.7e-09 35.5 0.1 0.12 11.8 0.0 4.2 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 CBZ29199.1 - 1.1e-07 31.9 0.0 0.018 14.9 0.0 3.3 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 CBZ29199.1 - 1.4e-06 27.9 0.0 0.089 12.5 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain FtsK_SpoIIIE PF01580.18 CBZ29199.1 - 1.1e-05 24.9 0.0 0.016 14.6 0.0 2.6 2 0 0 2 2 2 2 FtsK/SpoIIIE family AAA_16 PF13191.6 CBZ29199.1 - 3e-05 24.5 0.4 0.077 13.4 0.1 3.0 2 0 0 2 2 2 2 AAA ATPase domain T2SSE PF00437.20 CBZ29199.1 - 8.4e-05 21.8 0.0 0.35 9.9 0.0 2.3 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_22 PF13401.6 CBZ29199.1 - 0.00046 20.5 1.6 0.25 11.6 0.1 2.8 2 0 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.23 CBZ29199.1 - 0.00072 19.6 0.2 0.47 10.5 0.0 2.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase TrwB_AAD_bind PF10412.9 CBZ29199.1 - 0.00097 18.2 0.3 0.63 8.9 0.1 2.3 2 0 0 2 2 2 2 Type IV secretion-system coupling protein DNA-binding domain AAA_23 PF13476.6 CBZ29199.1 - 0.0014 19.1 0.0 1.6 9.2 0.0 2.2 2 0 0 2 2 2 2 AAA domain AAA_30 PF13604.6 CBZ29199.1 - 0.0075 16.0 0.6 3.9 7.1 0.1 2.6 2 0 0 2 2 2 2 AAA domain MeaB PF03308.16 CBZ29199.1 - 0.016 14.2 0.6 2.5 7.0 0.2 2.4 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_25 PF13481.6 CBZ29199.1 - 0.017 14.7 0.7 1.8 8.1 0.0 2.6 2 0 0 2 2 2 0 AAA domain DUF87 PF01935.17 CBZ29199.1 - 0.018 15.2 4.3 0.83 9.7 0.1 2.2 2 0 0 2 2 2 0 Helicase HerA, central domain RsgA_GTPase PF03193.16 CBZ29199.1 - 0.021 14.7 0.3 2.2 8.2 0.0 2.4 2 0 0 2 2 2 0 RsgA GTPase NACHT PF05729.12 CBZ29199.1 - 0.029 14.3 0.9 3 7.7 0.1 2.5 2 0 0 2 2 2 0 NACHT domain AAA_24 PF13479.6 CBZ29199.1 - 0.15 11.8 0.0 1.4 8.6 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 CBZ29199.1 - 0.15 11.5 0.2 15 5.1 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region cobW PF02492.19 CBZ29199.1 - 0.35 10.4 4.1 6.3 6.4 0.4 2.5 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain ATPase PF06745.13 CBZ29199.1 - 0.38 10.0 0.6 17 4.7 0.0 2.6 3 0 0 3 3 3 0 KaiC Dynamin_N PF00350.23 CBZ29199.1 - 0.72 9.9 3.0 21 5.1 0.2 2.3 2 0 0 2 2 2 0 Dynamin family AAA_33 PF13671.6 CBZ29199.1 - 0.74 10.0 3.1 8.1 6.6 0.4 2.8 2 0 0 2 2 2 0 AAA domain Synthase_beta PF11421.8 CBZ29199.1 - 8.2 7.2 7.0 4.4 8.1 0.1 3.2 2 0 0 2 2 2 0 ATP synthase F1 beta subunit LRR_8 PF13855.6 CBZ29200.1 - 1.7e-09 37.3 0.0 0.00049 19.8 0.0 2.9 2 1 1 3 3 3 3 Leucine rich repeat LRRNT_2 PF08263.12 CBZ29200.1 - 0.037 14.4 0.1 0.037 14.4 0.1 2.9 4 0 0 4 4 4 0 Leucine rich repeat N-terminal domain LRR_8 PF13855.6 CBZ29201.1 - 5.5e-10 38.9 0.1 0.00039 20.1 0.1 3.2 2 2 1 3 3 3 3 Leucine rich repeat LRRNT_2 PF08263.12 CBZ29201.1 - 0.04 14.2 0.3 0.04 14.2 0.3 3.2 4 1 0 4 4 4 0 Leucine rich repeat N-terminal domain Herpes_UL32 PF06070.11 CBZ29201.1 - 7.5 4.2 8.0 9.7 3.8 8.0 1.1 1 0 0 1 1 1 0 Herpesvirus large structural phosphoprotein UL32 LRR_8 PF13855.6 CBZ29202.1 - 8.4e-07 28.7 0.1 0.00036 20.3 0.0 2.4 1 1 2 3 3 3 3 Leucine rich repeat LRRNT_2 PF08263.12 CBZ29202.1 - 0.034 14.4 0.4 0.034 14.4 0.4 3.6 4 0 0 4 4 4 0 Leucine rich repeat N-terminal domain KAR9 PF08580.10 CBZ29202.1 - 1.9 7.0 5.1 1.9 6.9 5.1 1.1 1 0 0 1 1 1 0 Yeast cortical protein KAR9 LRR_8 PF13855.6 CBZ29203.1 - 9.9e-06 25.2 0.0 0.032 14.0 0.1 3.0 2 1 3 5 5 5 4 Leucine rich repeat LRR_4 PF12799.7 CBZ29203.1 - 0.0032 17.8 1.0 0.54 10.8 0.2 3.1 2 1 1 3 3 3 1 Leucine Rich repeats (2 copies) DUF3338 PF11819.8 CBZ29203.1 - 0.19 11.7 0.0 6.6 6.7 0.0 2.8 1 1 2 3 3 3 0 Domain of unknown function (DUF3338) LRR_4 PF12799.7 CBZ29205.1 - 5.1e-13 49.0 11.7 1.4 9.5 0.0 10.6 9 2 2 13 13 13 3 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 CBZ29205.1 - 1.5e-07 30.9 9.6 1.6 9.0 0.0 10.8 13 0 0 13 13 13 1 Leucine Rich repeat LRR_8 PF13855.6 CBZ29205.1 - 0.0096 15.7 18.1 0.47 10.3 0.1 8.3 10 0 0 10 10 10 2 Leucine rich repeat Paramyxo_P_V_N PF13825.6 CBZ29205.1 - 0.02 14.4 0.7 0.036 13.5 0.7 1.3 1 0 0 1 1 1 0 Paramyxovirus structural protein V/P N-terminus TTSSLRR PF12468.8 CBZ29205.1 - 0.027 14.7 0.2 0.064 13.5 0.2 1.6 1 0 0 1 1 1 0 Type III secretion system leucine rich repeat protein Cwf_Cwc_15 PF04889.12 CBZ29207.1 - 0.072 12.8 1.5 0.12 12.1 1.5 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein DUF4797 PF16051.5 CBZ29209.1 - 0.012 15.6 1.1 0.081 12.9 1.3 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4797) Pkinase PF00069.25 CBZ29210.1 - 3.7e-39 134.7 0.0 5.4e-27 94.8 0.0 2.5 3 0 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ29210.1 - 1.2e-20 73.9 0.0 1e-09 38.1 0.0 2.8 3 0 0 3 3 3 2 Protein tyrosine kinase PH_3 PF14593.6 CBZ29210.1 - 0.00031 20.8 0.0 0.0015 18.6 0.0 2.0 2 0 0 2 2 2 1 PH domain Kinase-like PF14531.6 CBZ29210.1 - 0.18 11.1 0.0 0.43 9.9 0.0 1.5 2 0 0 2 2 2 0 Kinase-like L51_S25_CI-B8 PF05047.16 CBZ29212.1 - 1.4e-10 40.9 0.0 2.9e-10 39.9 0.0 1.6 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain LysR_substrate PF03466.20 CBZ29212.1 - 0.11 11.9 0.2 0.51 9.7 0.0 1.9 2 0 0 2 2 2 0 LysR substrate binding domain Cmc1 PF08583.10 CBZ29215.1 - 0.38 10.8 3.5 0.88 9.6 3.5 1.7 1 1 0 1 1 1 0 Cytochrome c oxidase biogenesis protein Cmc1 like Ribosomal_L36 PF00444.18 CBZ29216.1 - 0.00076 19.6 0.1 0.0017 18.5 0.1 1.6 1 0 0 1 1 1 1 Ribosomal protein L36 LRR_4 PF12799.7 CBZ29217.1 - 1.2e-34 117.7 25.1 0.00035 20.9 2.3 12.7 11 1 1 12 12 12 10 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CBZ29217.1 - 1.9e-13 50.0 30.4 9.1e-05 22.1 1.7 9.9 7 2 3 10 10 10 6 Leucine rich repeat LRR_6 PF13516.6 CBZ29217.1 - 2.4e-09 36.5 30.0 1.2 9.4 0.0 15.0 18 0 0 18 18 18 2 Leucine Rich repeat LRR_2 PF07723.13 CBZ29217.1 - 0.057 14.1 0.8 33 5.3 0.1 4.9 4 0 0 4 4 4 0 Leucine Rich Repeat LRR_1 PF00560.33 CBZ29217.1 - 0.15 12.7 12.5 59 4.8 0.0 8.8 9 2 0 9 9 9 0 Leucine Rich Repeat TP_methylase PF00590.20 CBZ29218.1 - 6.2e-20 72.0 0.0 1.1e-19 71.2 0.0 1.4 1 1 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases NolV PF06635.12 CBZ29218.1 - 0.0063 15.9 0.0 0.01 15.2 0.0 1.3 1 0 0 1 1 1 1 Nodulation protein NolV DUF4434 PF14488.6 CBZ29218.1 - 0.027 14.5 0.0 0.053 13.5 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4434) NTPase_I-T PF01931.18 CBZ29219.1 - 1.7e-52 177.5 0.1 1.9e-52 177.4 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function DUF84 Thiolase_N PF00108.23 CBZ29220.1 - 1.1e-41 142.9 0.9 2e-41 142.1 0.9 1.4 1 1 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 CBZ29220.1 - 2.9e-34 117.3 0.0 6.4e-34 116.2 0.0 1.6 1 0 0 1 1 1 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 CBZ29220.1 - 7e-05 22.5 2.2 0.00028 20.5 2.2 1.9 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain SpoVAD PF07451.11 CBZ29220.1 - 0.026 13.3 0.0 0.065 11.9 0.0 1.6 1 0 0 1 1 1 0 Stage V sporulation protein AD (SpoVAD) ACP_syn_III PF08545.10 CBZ29220.1 - 0.076 12.9 1.1 3.2 7.7 0.5 2.5 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Thiolase_N PF00108.23 CBZ29221.1 - 2.5e-60 204.0 0.3 4.4e-60 203.2 0.3 1.4 1 1 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 CBZ29221.1 - 5e-35 119.8 0.0 1.4e-34 118.3 0.0 1.8 2 0 0 2 2 2 1 Thiolase, C-terminal domain SpoVAD PF07451.11 CBZ29221.1 - 1.1e-05 24.3 0.0 2.6e-05 23.1 0.0 1.5 1 0 0 1 1 1 1 Stage V sporulation protein AD (SpoVAD) ketoacyl-synt PF00109.26 CBZ29221.1 - 8.1e-05 22.3 2.2 0.00032 20.4 2.2 1.9 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain FAE1_CUT1_RppA PF08392.12 CBZ29221.1 - 0.0011 18.3 0.2 0.0026 17.1 0.2 1.5 1 0 0 1 1 1 1 FAE1/Type III polyketide synthase-like protein ACP_syn_III PF08545.10 CBZ29221.1 - 0.078 12.8 1.2 3.6 7.5 0.5 2.7 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III zf-MYND PF01753.18 CBZ29222.1 - 1.8e-10 40.7 8.4 1.8e-10 40.7 8.4 2.2 2 0 0 2 2 2 1 MYND finger zf-C6H2 PF15801.5 CBZ29222.1 - 0.00036 20.8 11.6 0.00097 19.4 11.6 1.8 1 0 0 1 1 1 1 zf-MYND-like zinc finger, mRNA-binding zf-Mss51 PF13824.6 CBZ29222.1 - 0.35 11.0 5.2 1.2 9.3 5.2 1.9 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 Sld5 PF05916.11 CBZ29223.1 - 3.1e-09 37.3 0.0 4e-09 36.9 0.0 1.2 1 0 0 1 1 1 1 GINS complex protein Gpi1 PF05024.15 CBZ29226.1 - 0.039 14.0 0.1 0.13 12.3 0.0 2.0 2 0 0 2 2 2 0 N-acetylglucosaminyl transferase component (Gpi1) Anophelin PF10731.9 CBZ29226.1 - 0.071 13.0 0.7 0.25 11.2 0.1 2.3 2 0 0 2 2 2 0 Thrombin inhibitor from mosquito PPR_2 PF13041.6 CBZ29227.1 - 0.0023 18.1 0.4 29 5.0 0.0 4.4 4 0 0 4 4 4 1 PPR repeat family PPR_3 PF13812.6 CBZ29227.1 - 0.0059 16.7 0.8 6.2 7.0 0.0 3.1 3 0 0 3 3 3 2 Pentatricopeptide repeat domain Cullin_Nedd8 PF10557.9 CBZ29229.1 - 1.6e-12 47.2 2.0 4.6e-12 45.8 2.0 1.8 1 0 0 1 1 1 1 Cullin protein neddylation domain Cullin PF00888.22 CBZ29229.1 - 0.00053 18.7 0.0 0.018 13.7 0.0 2.3 2 0 0 2 2 2 2 Cullin family NAP PF00956.18 CBZ29232.1 - 3.2e-76 256.1 0.3 3.2e-76 256.1 0.3 1.7 2 0 0 2 2 2 1 Nucleosome assembly protein (NAP) CENP-B_dimeris PF09026.10 CBZ29232.1 - 0.062 13.7 19.5 0.32 11.4 9.6 2.7 2 0 0 2 2 2 0 Centromere protein B dimerisation domain Nop14 PF04147.12 CBZ29232.1 - 2.3 6.3 11.7 3.4 5.8 11.7 1.2 1 0 0 1 1 1 0 Nop14-like family BUD22 PF09073.10 CBZ29232.1 - 5.3 6.3 19.1 0.27 10.5 12.9 1.7 1 1 0 2 2 2 0 BUD22 Cwf_Cwc_15 PF04889.12 CBZ29232.1 - 6.7 6.4 21.0 0.45 10.2 5.2 2.7 3 0 0 3 3 3 0 Cwf15/Cwc15 cell cycle control protein Ni_hydr_CYTB PF01292.20 CBZ29234.1 - 9.3 5.8 8.4 0.5 9.9 0.9 2.4 3 0 0 3 3 3 0 Prokaryotic cytochrome b561 TRAM_LAG1_CLN8 PF03798.16 CBZ29235.1 - 3.3e-40 137.9 12.5 3.3e-40 137.9 12.5 2.2 2 1 1 3 3 3 1 TLC domain CCSMST1 PF15013.6 CBZ29235.1 - 0.087 13.0 0.1 0.38 10.9 0.0 2.2 2 0 0 2 2 2 0 CCSMST1 family Aa_trans PF01490.18 CBZ29236.1 - 8.4e-45 153.2 17.6 1e-44 152.9 17.6 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 CBZ29236.1 - 4.8e-09 35.8 9.3 4.8e-09 35.8 9.3 2.4 2 1 0 2 2 2 2 Tryptophan/tyrosine permease family Aa_trans PF01490.18 CBZ29237.1 - 2.4e-44 151.7 17.9 2.9e-44 151.4 17.9 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 CBZ29237.1 - 5.1e-09 35.7 9.8 5.1e-09 35.7 9.8 2.4 3 0 0 3 3 3 2 Tryptophan/tyrosine permease family AA_permease_2 PF13520.6 CBZ29237.1 - 4.9e-07 28.9 25.8 4.9e-07 28.9 25.8 2.1 2 0 0 2 2 2 1 Amino acid permease Pkinase PF00069.25 CBZ29238.1 - 2.6e-17 63.1 0.0 4.5e-17 62.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ29238.1 - 2.1e-10 40.4 0.0 9.5e-09 34.9 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_Tyr PF07714.17 CBZ29239.1 - 1.7e-12 47.2 0.0 1.3e-11 44.3 0.0 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 CBZ29239.1 - 6.8e-12 45.3 0.0 1.4e-11 44.3 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Orf78 PF06024.12 CBZ29241.1 - 0.076 13.3 0.0 0.17 12.2 0.0 1.5 1 0 0 1 1 1 0 Orf78 (ac78) Glycos_transf_1 PF00534.20 CBZ29242.1 - 2.8e-14 53.0 0.0 9.9e-14 51.2 0.0 1.9 2 1 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 CBZ29242.1 - 9.9e-12 45.4 0.0 6.4e-11 42.8 0.0 2.2 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 CBZ29242.1 - 1e-05 25.8 0.0 2.8e-05 24.4 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 CBZ29242.1 - 8.1e-05 22.7 1.4 0.00014 21.9 0.3 2.1 2 0 0 2 2 2 1 Glycosyltransferase Family 4 Glyco_transf_90 PF05686.12 CBZ29242.1 - 0.0042 16.1 0.0 0.0081 15.1 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 90 Glycos_transf_1 PF00534.20 CBZ29243.1 - 4.1e-13 49.2 0.0 1.2e-12 47.7 0.0 1.7 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 CBZ29243.1 - 1.9e-11 44.6 0.0 9.5e-11 42.3 0.0 2.0 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 CBZ29243.1 - 4.4e-05 23.5 0.2 0.00017 21.6 0.2 2.0 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glycos_transf_1 PF00534.20 CBZ29244.1 - 7.1e-15 55.0 0.0 3.4e-14 52.7 0.0 2.1 2 1 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 CBZ29244.1 - 4e-12 46.7 0.1 3.8e-11 43.6 0.0 2.4 3 0 0 3 3 3 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 CBZ29244.1 - 3.9e-06 27.2 0.0 1.1e-05 25.7 0.0 1.8 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 CBZ29244.1 - 5.2e-05 23.3 2.2 6.8e-05 22.9 0.6 2.0 2 0 0 2 2 2 1 Glycosyltransferase Family 4 Glyco_transf_90 PF05686.12 CBZ29244.1 - 0.0053 15.7 0.1 0.011 14.7 0.0 1.4 2 0 0 2 2 2 1 Glycosyl transferase family 90 Peptidase_M20 PF01546.28 CBZ29245.1 - 3e-16 59.8 0.1 3.8e-16 59.4 0.1 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 CBZ29245.1 - 3e-06 27.1 0.0 5.5e-06 26.3 0.0 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain ubiquitin PF00240.23 CBZ29246.1 - 2.1e-33 113.9 0.2 2.7e-33 113.5 0.2 1.2 1 0 0 1 1 1 1 Ubiquitin family Ribosomal_L40e PF01020.17 CBZ29246.1 - 1.1e-27 95.7 10.6 1.6e-27 95.1 10.6 1.3 1 0 0 1 1 1 1 Ribosomal L40e family Rad60-SLD PF11976.8 CBZ29246.1 - 5.7e-17 61.3 0.2 8e-17 60.8 0.2 1.2 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 CBZ29246.1 - 2.4e-05 24.7 0.0 0.0001 22.6 0.0 1.9 1 1 0 1 1 1 1 Ubiquitin-like domain TBK1_ULD PF18396.1 CBZ29246.1 - 0.0029 17.5 0.0 0.0038 17.1 0.0 1.2 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain Ubiquitin_5 PF18037.1 CBZ29246.1 - 0.0037 17.6 0.1 0.0076 16.6 0.0 1.5 2 0 0 2 2 2 1 Ubiquitin-like domain Rad60-SLD_2 PF13881.6 CBZ29246.1 - 0.0071 16.4 0.1 0.014 15.5 0.1 1.6 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_4 PF18036.1 CBZ29246.1 - 0.043 13.9 0.6 7.6 6.7 0.1 2.2 2 0 0 2 2 2 0 Ubiquitin-like domain UPF0547 PF10571.9 CBZ29246.1 - 3.3 7.9 6.3 5.2 7.2 6.3 1.3 1 0 0 1 1 1 0 Uncharacterised protein family UPF0547 RINGv PF12906.7 CBZ29248.1 - 8.3e-12 45.0 6.5 8.3e-12 45.0 6.5 1.9 2 0 0 2 2 2 1 RING-variant domain Dus PF01207.17 CBZ29249.1 - 8.9e-52 176.1 0.7 1.6e-20 73.4 0.0 4.2 4 0 0 4 4 4 4 Dihydrouridine synthase (Dus) DHO_dh PF01180.21 CBZ29249.1 - 0.16 11.2 0.0 0.82 8.8 0.0 1.9 2 0 0 2 2 2 0 Dihydroorotate dehydrogenase MPM1 PF17234.2 CBZ29250.1 - 9.4 6.5 6.7 30 4.8 0.4 2.3 2 0 0 2 2 2 0 Mitochondrial peculiar membrane protein 1 Thioredoxin_8 PF13905.6 CBZ29252.1 - 4.9e-23 81.3 0.0 7.3e-23 80.7 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin-like Redoxin PF08534.10 CBZ29252.1 - 1.2e-09 38.0 0.0 1.7e-09 37.5 0.0 1.2 1 0 0 1 1 1 1 Redoxin Thioredoxin PF00085.20 CBZ29252.1 - 2.7e-09 37.0 0.1 3.2e-07 30.3 0.1 2.1 2 0 0 2 2 2 1 Thioredoxin AhpC-TSA PF00578.21 CBZ29252.1 - 6.8e-07 29.3 0.0 1e-06 28.7 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_2 PF13098.6 CBZ29252.1 - 1.3e-05 25.6 0.0 2e-05 25.0 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_7 PF13899.6 CBZ29252.1 - 0.00021 21.4 0.0 0.00032 20.8 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin-like TraF PF13728.6 CBZ29252.1 - 0.00028 20.8 0.0 0.00093 19.1 0.0 1.7 2 0 0 2 2 2 1 F plasmid transfer operon protein Thioredoxin_9 PF14595.6 CBZ29252.1 - 0.017 14.9 0.0 0.036 13.8 0.0 1.5 2 0 0 2 2 2 0 Thioredoxin Glutaredoxin PF00462.24 CBZ29252.1 - 0.041 14.1 0.2 2 8.7 0.1 2.5 2 1 1 3 3 3 0 Glutaredoxin DUF5486 PF17588.2 CBZ29252.1 - 0.68 9.9 2.8 0.63 10.0 0.7 1.9 1 1 1 2 2 2 0 Family of unknown function (DUF5486) Thioredoxin_8 PF13905.6 CBZ29253.1 - 1.3e-23 83.1 0.0 1.9e-23 82.6 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin PF00085.20 CBZ29253.1 - 4.7e-08 33.0 0.0 5.6e-07 29.5 0.0 2.0 2 0 0 2 2 2 1 Thioredoxin Redoxin PF08534.10 CBZ29253.1 - 5.4e-08 32.7 0.0 7.1e-08 32.3 0.0 1.2 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 CBZ29253.1 - 6.5e-08 32.5 0.0 9.2e-08 32.0 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_2 PF13098.6 CBZ29253.1 - 7.3e-06 26.4 0.0 1.3e-05 25.6 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin-like domain TraF PF13728.6 CBZ29253.1 - 3.7e-05 23.6 0.0 7.8e-05 22.6 0.0 1.6 1 1 0 1 1 1 1 F plasmid transfer operon protein Thioredoxin_7 PF13899.6 CBZ29253.1 - 0.0031 17.7 0.0 0.0055 16.9 0.0 1.6 1 1 0 1 1 1 1 Thioredoxin-like Thioredoxin_9 PF14595.6 CBZ29253.1 - 0.0088 15.8 0.0 0.059 13.1 0.0 2.0 2 0 0 2 2 2 1 Thioredoxin AAA_25 PF13481.6 CBZ29253.1 - 0.036 13.6 0.0 0.048 13.2 0.0 1.4 1 1 0 1 1 1 0 AAA domain GBP_PSP PF02425.15 CBZ29254.1 - 0.11 12.2 0.1 0.24 11.1 0.1 1.5 1 0 0 1 1 1 0 Paralytic/GBP/PSP peptide Unstab_antitox PF09720.10 CBZ29255.1 - 0.12 12.5 0.7 0.3 11.2 0.7 1.7 1 0 0 1 1 1 0 Putative addiction module component Peptidase_M8 PF01457.16 CBZ29256.1 - 1.8e-130 436.1 0.0 3.6e-130 435.1 0.0 1.4 1 1 0 1 1 1 1 Leishmanolysin Peptidase_M20 PF01546.28 CBZ29258.1 - 6e-19 68.6 0.1 8.5e-19 68.1 0.1 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 CBZ29258.1 - 1e-09 38.2 0.0 1.9e-09 37.4 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain ubiquitin PF00240.23 CBZ29259.1 - 2.1e-33 113.9 0.2 2.7e-33 113.5 0.2 1.2 1 0 0 1 1 1 1 Ubiquitin family Ribosomal_L40e PF01020.17 CBZ29259.1 - 1.1e-27 95.7 10.6 1.6e-27 95.1 10.6 1.3 1 0 0 1 1 1 1 Ribosomal L40e family Rad60-SLD PF11976.8 CBZ29259.1 - 5.7e-17 61.3 0.2 8e-17 60.8 0.2 1.2 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 CBZ29259.1 - 2.4e-05 24.7 0.0 0.0001 22.6 0.0 1.9 1 1 0 1 1 1 1 Ubiquitin-like domain TBK1_ULD PF18396.1 CBZ29259.1 - 0.0029 17.5 0.0 0.0038 17.1 0.0 1.2 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain Ubiquitin_5 PF18037.1 CBZ29259.1 - 0.0037 17.6 0.1 0.0076 16.6 0.0 1.5 2 0 0 2 2 2 1 Ubiquitin-like domain Rad60-SLD_2 PF13881.6 CBZ29259.1 - 0.0071 16.4 0.1 0.014 15.5 0.1 1.6 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_4 PF18036.1 CBZ29259.1 - 0.043 13.9 0.6 7.6 6.7 0.1 2.2 2 0 0 2 2 2 0 Ubiquitin-like domain UPF0547 PF10571.9 CBZ29259.1 - 3.3 7.9 6.3 5.2 7.2 6.3 1.3 1 0 0 1 1 1 0 Uncharacterised protein family UPF0547 CRAL_TRIO PF00650.20 CBZ29261.1 - 9e-47 158.7 0.0 1.3e-46 158.2 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.6 CBZ29261.1 - 0.00047 20.3 0.3 0.0013 18.9 0.3 1.7 1 1 0 1 1 1 1 Divergent CRAL/TRIO domain CRAL_TRIO PF00650.20 CBZ29262.1 - 3.1e-46 157.0 0.0 5.2e-46 156.3 0.0 1.4 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.6 CBZ29262.1 - 0.0046 17.1 0.0 0.0086 16.2 0.0 1.4 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain Sif PF06767.11 CBZ29262.1 - 0.052 12.5 0.0 1.2 8.1 0.0 2.1 2 0 0 2 2 2 0 Sif protein CRAL_TRIO PF00650.20 CBZ29263.1 - 3e-37 127.8 0.0 5.2e-37 127.0 0.0 1.4 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.6 CBZ29263.1 - 0.00093 19.4 0.0 0.0019 18.4 0.0 1.5 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain CorA PF01544.18 CBZ29264.1 - 2.9e-05 23.5 3.3 0.00072 19.0 1.5 2.2 2 0 0 2 2 2 2 CorA-like Mg2+ transporter protein SR-25 PF10500.9 CBZ29264.1 - 1.7 8.2 20.5 4 7.0 20.5 1.6 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Tis11B_N PF04553.12 CBZ29268.1 - 0.0034 17.9 4.1 0.013 16.0 4.1 2.0 2 0 0 2 2 2 1 Tis11B like protein, N terminus tRNA_lig_CPD PF08302.11 CBZ29270.1 - 6.9e-10 38.8 0.0 7.2e-09 35.5 0.0 2.2 1 1 0 2 2 2 1 Fungal tRNA ligase phosphodiesterase domain AAA_33 PF13671.6 CBZ29270.1 - 0.00016 21.8 0.0 0.0005 20.2 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_15 PF13175.6 CBZ29270.1 - 0.00062 19.6 0.0 0.0009 19.0 0.0 1.2 1 0 0 1 1 1 1 AAA ATPase domain ATP_bind_1 PF03029.17 CBZ29270.1 - 0.00065 19.5 0.0 0.0011 18.8 0.0 1.3 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_21 PF13304.6 CBZ29270.1 - 0.0025 17.7 0.0 0.0045 16.8 0.0 1.3 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_28 PF13521.6 CBZ29270.1 - 0.0027 18.0 0.0 0.45 10.7 0.0 3.9 5 0 0 5 5 5 1 AAA domain tRNA_lig_kinase PF08303.11 CBZ29270.1 - 0.0027 17.8 0.0 0.0074 16.4 0.0 1.7 1 1 0 1 1 1 1 tRNA ligase kinase domain ABC_tran PF00005.27 CBZ29270.1 - 0.0043 17.6 0.0 0.01 16.3 0.0 1.6 1 0 0 1 1 1 1 ABC transporter AAA_29 PF13555.6 CBZ29270.1 - 0.0047 16.6 0.0 0.02 14.6 0.0 2.0 2 0 0 2 2 2 1 P-loop containing region of AAA domain SWM_repeat PF13753.6 CBZ29270.1 - 0.032 14.4 0.7 0.086 13.0 0.3 1.9 2 0 0 2 2 2 0 Putative flagellar system-associated repeat AAA_18 PF13238.6 CBZ29270.1 - 0.093 13.3 0.0 0.24 12.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain Peroxin-3 PF04882.12 CBZ29271.1 - 1.9 7.4 6.9 4.2 6.2 6.9 1.5 1 0 0 1 1 1 0 Peroxin-3 Aldo_ket_red PF00248.21 CBZ29272.1 - 6.9e-50 169.9 0.2 6.4e-48 163.4 0.2 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family DUF1304 PF06993.12 CBZ29274.1 - 0.096 12.7 0.0 0.26 11.3 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1304) HisKA_3 PF07730.13 CBZ29274.1 - 0.53 10.8 3.6 0.94 10.0 0.9 2.9 2 0 0 2 2 2 0 Histidine kinase ECH_1 PF00378.20 CBZ29283.1 - 6.5e-47 159.9 0.0 8.3e-47 159.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 CBZ29283.1 - 9.2e-11 41.8 0.0 1.6e-10 41.0 0.0 1.3 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Peptidase_S49 PF01343.18 CBZ29283.1 - 0.079 12.9 0.3 4.8 7.1 0.0 2.3 2 0 0 2 2 2 0 Peptidase family S49 Peptidase_M1_N PF17900.1 CBZ29284.1 - 1.3e-07 31.9 0.0 2e-07 31.4 0.0 1.2 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain Peptidase_M1 PF01433.20 CBZ29284.1 - 3.5e-07 30.0 0.0 5.6e-07 29.4 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M1 domain DA1-like PF12315.8 CBZ29284.1 - 0.0043 16.5 0.0 0.0079 15.6 0.0 1.3 1 0 0 1 1 1 1 Protein DA1 SEN1_N PF12726.7 CBZ29285.1 - 0.076 11.2 0.0 0.12 10.5 0.0 1.2 1 0 0 1 1 1 0 SEN1 N terminal Arf PF00025.21 CBZ29286.1 - 8.8e-75 250.0 0.2 1e-74 249.8 0.2 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 CBZ29286.1 - 5.2e-15 55.7 0.1 7.1e-15 55.3 0.1 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 CBZ29286.1 - 4.6e-14 52.3 0.0 5.5e-14 52.0 0.0 1.0 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.22 CBZ29286.1 - 2.2e-13 50.1 0.0 2.4e-13 50.0 0.0 1.1 1 0 0 1 1 1 1 Ras family G-alpha PF00503.20 CBZ29286.1 - 9.7e-12 44.7 0.4 4.1e-08 32.8 0.1 2.4 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.12 CBZ29286.1 - 2.8e-07 30.1 0.0 3.7e-07 29.8 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 CBZ29286.1 - 2e-05 24.6 0.0 3.2e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.18 CBZ29286.1 - 0.001 18.4 0.0 0.0012 18.2 0.0 1.2 1 0 0 1 1 1 1 6-phosphofructo-2-kinase GTP_EFTU PF00009.27 CBZ29286.1 - 0.023 14.2 0.1 0.099 12.2 0.0 1.7 1 1 1 2 2 2 0 Elongation factor Tu GTP binding domain AAA_33 PF13671.6 CBZ29286.1 - 0.15 12.2 0.1 0.17 12.0 0.1 1.4 1 1 0 1 1 1 0 AAA domain PEMT PF04191.13 CBZ29287.1 - 2.3e-31 108.4 3.0 4.8e-31 107.3 2.5 1.8 2 0 0 2 2 2 1 Phospholipid methyltransferase S1-P1_nuclease PF02265.16 CBZ29289.1 - 1.2e-65 221.8 0.0 1.5e-65 221.5 0.0 1.1 1 0 0 1 1 1 1 S1/P1 Nuclease TM_helix PF05552.12 CBZ29289.1 - 0.022 14.7 2.6 0.26 11.3 1.5 2.5 2 0 0 2 2 2 0 Conserved TM helix Zn_dep_PLPC PF00882.18 CBZ29289.1 - 0.057 13.4 0.0 0.09 12.8 0.0 1.4 1 0 0 1 1 1 0 Zinc dependent phospholipase C DUF3169 PF11368.8 CBZ29289.1 - 0.067 12.7 0.3 0.11 12.0 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3169) Stevor PF17410.2 CBZ29289.1 - 0.09 12.3 0.8 0.24 10.9 0.8 1.6 2 0 0 2 2 2 0 Subtelomeric Variable Open Reading frame DUF2937 PF11157.8 CBZ29289.1 - 0.19 11.4 0.1 0.19 11.4 0.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2937) SNF2_N PF00176.23 CBZ29290.1 - 3.3e-41 141.2 0.1 1.3e-40 139.3 0.1 2.0 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 CBZ29290.1 - 3.1e-11 43.6 0.1 1.4e-07 31.8 0.0 3.3 3 0 0 3 3 3 2 Helicase conserved C-terminal domain ResIII PF04851.15 CBZ29290.1 - 3.4e-07 30.4 0.0 8.2e-07 29.2 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.8 CBZ29290.1 - 0.00078 18.7 0.0 0.22 10.7 0.0 2.2 2 0 0 2 2 2 2 Class II histone deacetylase complex subunits 2 and 3 AAA_22 PF13401.6 CBZ29290.1 - 0.018 15.3 0.2 0.25 11.6 0.0 2.6 3 0 0 3 3 3 0 AAA domain AAA_19 PF13245.6 CBZ29290.1 - 0.074 13.4 0.2 0.94 9.8 0.1 2.5 2 1 0 2 2 2 0 AAA domain SWI2_SNF2 PF18766.1 CBZ29290.1 - 0.088 12.5 0.0 0.16 11.7 0.0 1.3 1 0 0 1 1 1 0 SWI2/SNF2 ATPase ECH_1 PF00378.20 CBZ29291.1 - 1.6e-45 155.4 0.0 2.1e-45 155.0 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 CBZ29291.1 - 2.5e-09 37.1 0.0 5.5e-09 36.0 0.0 1.5 2 0 0 2 2 2 1 Enoyl-CoA hydratase/isomerase Hydrolase_6 PF13344.6 CBZ29292.1 - 4.4e-20 71.7 0.0 2.1e-19 69.5 0.0 2.0 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 CBZ29292.1 - 7.1e-18 64.5 0.0 1.9e-17 63.1 0.0 1.7 1 0 0 1 1 1 1 HAD-hyrolase-like PGP_phosphatase PF09419.10 CBZ29292.1 - 1.4e-05 24.8 0.0 5.7e-05 22.8 0.0 1.9 2 0 0 2 2 2 1 Mitochondrial PGP phosphatase Hydrolase PF00702.26 CBZ29292.1 - 6.2e-05 23.4 0.0 0.035 14.4 0.0 2.4 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 CBZ29292.1 - 0.0055 16.8 0.0 0.05 13.7 0.0 2.1 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Symplekin_C PF12295.8 CBZ29293.1 - 2.4e-13 50.6 0.4 6e-12 46.0 0.1 2.8 2 0 0 2 2 2 1 Symplekin tight junction protein C terminal WD40 PF00400.32 CBZ29295.1 - 0.011 16.5 0.2 4.4 8.3 0.0 3.8 3 0 0 3 3 3 0 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBZ29295.1 - 0.094 13.0 0.0 2.2 8.6 0.0 2.6 2 1 1 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain Cation_efflux PF01545.21 CBZ29297.1 - 6.1e-40 137.1 9.5 8.7e-40 136.6 9.5 1.2 1 0 0 1 1 1 1 Cation efflux family Phenol_monoox PF04663.12 CBZ29299.1 - 0.035 14.2 0.3 7.9 6.7 0.0 2.5 2 0 0 2 2 2 0 Phenol hydroxylase conserved region DUF5407 PF17401.2 CBZ29299.1 - 0.049 13.9 0.7 0.085 13.1 0.7 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5407) UBA_5 PF16577.5 CBZ29301.1 - 0.11 12.7 0.0 1.5 9.0 0.0 2.4 2 0 0 2 2 2 0 UBA domain PRP8_domainIV PF12134.8 CBZ29302.1 - 0.073 12.7 0.2 0.18 11.5 0.0 1.6 2 0 0 2 2 2 0 PRP8 domain IV core Lipase_3 PF01764.25 CBZ29304.1 - 5.8e-36 123.5 0.0 1.1e-35 122.6 0.0 1.5 1 0 0 1 1 1 1 Lipase (class 3) Hydrolase_4 PF12146.8 CBZ29304.1 - 2e-05 24.0 0.0 2.8e-05 23.5 0.0 1.4 1 1 0 1 1 1 1 Serine aminopeptidase, S33 DUF2974 PF11187.8 CBZ29304.1 - 0.00016 21.3 0.2 0.00049 19.7 0.2 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF2974) Abhydrolase_6 PF12697.7 CBZ29304.1 - 0.0031 18.2 0.1 0.004 17.8 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Fer2 PF00111.27 CBZ29307.1 - 4.2e-11 42.6 1.4 5.6e-11 42.2 1.4 1.2 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain HECT_2 PF09814.9 CBZ29307.1 - 0.011 14.7 0.1 0.012 14.5 0.1 1.2 1 0 0 1 1 1 0 HECT-like Ubiquitin-conjugating enzyme (E2)-binding Fer2 PF00111.27 CBZ29308.1 - 8.7e-11 41.6 2.0 1.2e-10 41.2 2.0 1.2 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain NifU PF01106.17 CBZ29308.1 - 0.082 13.1 0.5 0.16 12.1 0.5 1.5 1 0 0 1 1 1 0 NifU-like domain Fer2 PF00111.27 CBZ29309.1 - 5.8e-10 39.0 1.4 7.8e-10 38.6 1.4 1.2 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Cytochrome_C7 PF14522.6 CBZ29309.1 - 0.091 12.8 1.4 0.19 11.7 1.4 1.6 1 1 0 1 1 1 0 Cytochrome c7 and related cytochrome c Fer2 PF00111.27 CBZ29310.1 - 4.3e-07 29.8 4.4 8.6e-07 28.8 4.4 1.5 1 1 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain EGF_2 PF07974.13 CBZ29311.1 - 0.0044 17.3 14.3 0.0044 17.3 14.3 5.9 6 1 0 6 6 6 2 EGF-like domain EGF_2 PF07974.13 CBZ29312.1 - 0.0044 17.3 14.3 0.0044 17.3 14.3 5.7 5 1 0 5 5 5 2 EGF-like domain ADH_N PF08240.12 CBZ29315.1 - 0.68 9.8 3.0 11 6.0 0.0 2.7 3 0 0 3 3 3 0 Alcohol dehydrogenase GroES-like domain UCR_hinge PF02320.16 CBZ29316.1 - 9.8e-17 60.9 5.2 1.6e-16 60.3 4.6 1.6 2 0 0 2 2 2 1 Ubiquinol-cytochrome C reductase hinge protein TerD PF02342.18 CBZ29317.1 - 4.4e-14 52.4 0.0 0.00041 19.9 0.0 3.3 3 0 0 3 3 3 3 TerD domain DUF4337 PF14235.6 CBZ29317.1 - 0.42 10.7 1.6 1.8 8.7 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4337) Calreticulin PF00262.18 CBZ29318.1 - 2.9e-74 250.1 12.8 2.1e-55 188.1 0.8 2.5 2 1 1 3 3 3 2 Calreticulin family Laminin_G_3 PF13385.6 CBZ29318.1 - 0.024 14.8 0.2 0.15 12.2 0.2 1.9 1 1 0 2 2 2 0 Concanavalin A-like lectin/glucanases superfamily RNA_pol_Rpb1_5 PF04998.17 CBZ29319.1 - 8.7e-98 327.0 0.2 1.4e-97 326.4 0.2 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_1 PF04997.12 CBZ29319.1 - 1.3e-95 320.4 2.0 8.4e-95 317.7 0.0 2.7 3 0 0 3 3 3 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_2 PF00623.20 CBZ29319.1 - 9.5e-71 237.4 0.5 2.7e-70 235.9 0.5 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_6 PF04992.14 CBZ29319.1 - 9.1e-49 165.9 0.9 1.6e-48 165.1 0.9 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 6 RNA_pol_Rpb1_3 PF04983.18 CBZ29319.1 - 3e-39 134.5 0.0 7.3e-39 133.2 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.17 CBZ29319.1 - 5.7e-29 100.2 0.1 1.9e-28 98.6 0.1 2.0 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 RNA_pol_Rpb1_7 PF04990.12 CBZ29319.1 - 8.6e-23 80.8 0.6 8.6e-23 80.8 0.6 1.9 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 7 PspA_IM30 PF04012.12 CBZ29319.1 - 0.032 13.8 1.9 0.078 12.5 1.9 1.6 1 0 0 1 1 1 0 PspA/IM30 family CRCB PF02537.15 CBZ29320.1 - 3.2e-20 72.2 18.7 1.2e-15 57.6 6.1 3.0 1 1 2 3 3 3 2 CrcB-like protein, Camphor Resistance (CrcB) Metallophos PF00149.28 CBZ29321.1 - 3.9e-37 128.7 0.2 5.1e-37 128.4 0.2 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 CBZ29321.1 - 1.6e-07 31.7 0.1 7.5e-07 29.5 0.0 2.0 2 0 0 2 2 2 1 Serine-threonine protein phosphatase N-terminal domain Pyr_redox_2 PF07992.14 CBZ29322.1 - 1.8e-46 158.7 0.4 2.5e-46 158.3 0.4 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 CBZ29322.1 - 1.7e-15 57.4 3.5 1.3e-13 51.2 0.0 2.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 CBZ29322.1 - 1.9e-15 57.1 0.6 8.5e-15 55.0 0.0 2.3 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox_3 PF13738.6 CBZ29322.1 - 7.1e-09 35.3 7.1 5.9e-05 22.5 0.0 2.7 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 CBZ29322.1 - 1.2e-08 34.8 0.1 1.2e-08 34.8 0.1 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase DAO PF01266.24 CBZ29322.1 - 4.6e-06 26.4 7.0 0.1 12.2 2.3 3.5 3 1 1 4 4 4 2 FAD dependent oxidoreductase ThiF PF00899.21 CBZ29322.1 - 2e-05 24.1 0.3 0.00015 21.2 0.1 2.2 1 1 1 2 2 2 1 ThiF family K_oxygenase PF13434.6 CBZ29322.1 - 3.1e-05 23.3 0.0 0.0024 17.1 0.0 2.5 1 1 1 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 CBZ29322.1 - 7.3e-05 22.9 5.2 0.063 13.5 1.3 2.6 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 CBZ29322.1 - 0.00011 21.5 10.5 0.0034 16.5 4.6 3.2 2 1 0 2 2 2 2 FAD binding domain Lycopene_cycl PF05834.12 CBZ29322.1 - 0.00012 21.3 0.1 0.048 12.7 0.0 2.4 2 0 0 2 2 2 2 Lycopene cyclase protein HI0933_like PF03486.14 CBZ29322.1 - 0.0003 19.6 10.0 0.027 13.2 2.1 3.3 3 1 0 3 3 3 2 HI0933-like protein 3HCDH_N PF02737.18 CBZ29322.1 - 0.00061 19.7 0.1 0.0012 18.8 0.1 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain GIDA PF01134.22 CBZ29322.1 - 0.00073 18.7 5.4 0.27 10.3 0.0 3.1 3 0 0 3 3 3 2 Glucose inhibited division protein A AlaDh_PNT_C PF01262.21 CBZ29322.1 - 0.0021 17.4 2.2 0.31 10.3 0.0 2.3 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain Thi4 PF01946.17 CBZ29322.1 - 0.0067 15.7 1.6 0.15 11.2 0.4 2.4 2 0 0 2 2 2 1 Thi4 family FAD_binding_3 PF01494.19 CBZ29322.1 - 0.034 13.4 6.6 0.13 11.4 1.9 2.5 2 1 0 2 2 2 0 FAD binding domain ApbA PF02558.16 CBZ29322.1 - 0.035 13.8 0.0 0.099 12.3 0.0 1.8 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA NAD_binding_9 PF13454.6 CBZ29322.1 - 0.051 13.6 2.6 2.7 8.0 0.5 3.3 2 2 1 3 3 3 0 FAD-NAD(P)-binding Shikimate_DH PF01488.20 CBZ29322.1 - 0.089 12.8 0.0 0.31 11.1 0.0 1.9 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase TrkA_N PF02254.18 CBZ29322.1 - 0.14 12.4 0.1 0.43 10.9 0.1 1.9 1 0 0 1 1 1 0 TrkA-N domain Pyr_redox_2 PF07992.14 CBZ29323.1 - 1.5e-42 145.8 0.1 2.2e-42 145.3 0.1 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 CBZ29323.1 - 3.2e-20 72.4 0.7 1.2e-19 70.6 0.0 2.4 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 CBZ29323.1 - 8.9e-17 61.4 0.3 2.2e-12 47.4 0.0 2.7 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 CBZ29323.1 - 1.4e-10 41.1 0.0 1.4e-10 41.1 0.0 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 CBZ29323.1 - 4.5e-09 36.4 0.9 0.00038 20.6 0.3 2.8 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain GIDA PF01134.22 CBZ29323.1 - 1.9e-08 33.8 1.8 1.5e-06 27.6 0.3 2.8 2 1 0 2 2 2 1 Glucose inhibited division protein A DAO PF01266.24 CBZ29323.1 - 7.5e-08 32.3 1.5 0.00015 21.5 0.0 3.0 3 0 0 3 3 3 2 FAD dependent oxidoreductase HI0933_like PF03486.14 CBZ29323.1 - 1.3e-06 27.5 2.6 8.1e-06 24.8 0.2 2.7 3 0 0 3 3 3 1 HI0933-like protein Pyr_redox_3 PF13738.6 CBZ29323.1 - 1.5e-06 27.7 8.5 0.00036 19.9 0.5 3.0 2 1 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 CBZ29323.1 - 2.2e-06 27.0 0.7 0.00072 18.7 0.0 2.3 2 0 0 2 2 2 2 Lycopene cyclase protein FAD_binding_2 PF00890.24 CBZ29323.1 - 2.8e-06 26.7 0.7 2.8e-06 26.7 0.7 2.5 3 0 0 3 3 3 1 FAD binding domain FAD_binding_3 PF01494.19 CBZ29323.1 - 4.9e-06 26.0 0.5 0.0026 17.1 0.0 3.1 4 0 0 4 4 4 2 FAD binding domain Thi4 PF01946.17 CBZ29323.1 - 5.1e-06 25.9 0.8 0.0016 17.8 0.0 2.9 3 0 0 3 3 3 1 Thi4 family AlaDh_PNT_C PF01262.21 CBZ29323.1 - 0.00018 20.9 0.1 0.43 9.9 0.1 2.4 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain PALP PF00291.25 CBZ29323.1 - 0.00034 20.1 0.1 0.0007 19.1 0.1 1.5 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme ThiF PF00899.21 CBZ29323.1 - 0.00083 18.8 0.1 0.0021 17.5 0.1 1.6 1 0 0 1 1 1 1 ThiF family TrkA_N PF02254.18 CBZ29323.1 - 0.0025 18.1 1.9 0.12 12.7 0.2 3.2 3 0 0 3 3 3 1 TrkA-N domain K_oxygenase PF13434.6 CBZ29323.1 - 0.0036 16.5 0.1 0.11 11.7 0.0 2.6 2 1 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.6 CBZ29323.1 - 0.029 14.4 1.4 0.3 11.1 0.1 2.8 2 1 0 2 2 2 0 FAD-NAD(P)-binding 3HCDH_N PF02737.18 CBZ29323.1 - 3.1 7.7 5.1 4.9 7.0 0.1 3.4 4 1 0 4 4 4 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Plasmodium_Vir PF05795.11 CBZ29326.1 - 0.22 10.9 3.0 0.34 10.3 3.0 1.2 1 0 0 1 1 1 0 Plasmodium vivax Vir protein DUF966 PF06136.13 CBZ29326.1 - 0.3 10.7 4.2 0.5 10.0 4.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF966) Endomucin PF07010.12 CBZ29326.1 - 0.36 10.8 33.7 0.7 9.8 33.7 1.4 1 0 0 1 1 1 0 Endomucin GREB1 PF15782.5 CBZ29326.1 - 0.47 7.5 6.1 0.65 7.1 6.1 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer PPR PF01535.20 CBZ29328.1 - 0.11 12.8 0.1 7.1 7.1 0.1 2.7 2 0 0 2 2 2 0 PPR repeat DNA_pol_A_exo1 PF01612.20 CBZ29329.1 - 4.7e-05 23.2 0.0 0.00017 21.4 0.0 1.9 2 0 0 2 2 2 1 3'-5' exonuclease MORN PF02493.20 CBZ29330.1 - 2.4e-30 102.6 47.7 6.9e-09 35.1 0.7 7.8 8 0 0 8 8 8 7 MORN repeat Kinesin PF00225.23 CBZ29330.1 - 1.3e-18 67.1 0.0 8.4e-18 64.4 0.0 2.1 1 1 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 CBZ29330.1 - 0.0034 17.3 0.0 0.0077 16.2 0.0 1.6 1 0 0 1 1 1 1 Microtubule binding Proteasom_PSMB PF10508.9 CBZ29330.1 - 0.053 12.0 9.4 0.012 14.1 6.1 1.5 2 0 0 2 2 2 0 Proteasome non-ATPase 26S subunit BRE1 PF08647.11 CBZ29330.1 - 0.16 12.1 31.8 0.2 11.8 8.3 4.4 4 0 0 4 4 4 0 BRE1 E3 ubiquitin ligase DUF3994 PF13159.6 CBZ29330.1 - 0.24 12.0 3.5 12 6.6 1.3 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF3994) DUF3048_C PF17479.2 CBZ29330.1 - 0.49 10.8 7.9 5.9 7.3 0.3 3.6 1 1 2 3 3 3 0 Protein of unknown function (DUF3048) C-terminal domain GIT_CC PF16559.5 CBZ29330.1 - 6 6.8 12.7 3.9 7.4 0.3 4.6 4 0 0 4 4 4 0 GIT coiled-coil Rho guanine nucleotide exchange factor Bap31 PF05529.12 CBZ29331.1 - 0.0013 18.6 2.4 0.0019 18.1 2.4 1.2 1 0 0 1 1 1 1 Bap31/Bap29 transmembrane region DUF2238 PF09997.9 CBZ29331.1 - 0.087 12.6 0.7 0.3 10.9 0.3 1.9 1 1 1 2 2 2 0 Predicted membrane protein (DUF2238) RCC1 PF00415.18 CBZ29332.1 - 4.9e-25 87.9 12.9 2.5e-13 50.4 0.0 7.6 6 2 0 6 6 6 4 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 CBZ29332.1 - 4.7e-19 67.7 13.6 0.00044 20.0 0.1 5.0 5 0 0 5 5 5 4 Regulator of chromosome condensation (RCC1) repeat EMP24_GP25L PF01105.24 CBZ29333.1 - 5e-33 114.6 0.0 6.7e-33 114.2 0.0 1.2 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD COPIIcoated_ERV PF07970.12 CBZ29334.1 - 4.3e-65 219.7 0.0 6.8e-65 219.0 0.0 1.3 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.6 CBZ29334.1 - 7.3e-25 87.1 0.2 7.3e-25 87.1 0.2 1.9 2 0 0 2 2 2 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) FH2 PF02181.23 CBZ29335.1 - 0.079 12.1 2.1 0.13 11.4 2.1 1.3 1 0 0 1 1 1 0 Formin Homology 2 Domain DUF725 PF05267.12 CBZ29335.1 - 0.08 12.9 0.3 0.13 12.2 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF725) Exonuc_VII_L PF02601.15 CBZ29335.1 - 2.6 7.6 8.0 3.8 7.0 8.0 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit RRM_1 PF00076.22 CBZ29337.1 - 9.6e-12 44.6 0.0 1.9e-11 43.6 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF4778 PF16008.5 CBZ29338.1 - 0.078 13.0 2.3 0.12 12.4 2.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4778) Arf PF00025.21 CBZ29339.1 - 2.5e-77 258.2 0.2 2.8e-77 258.1 0.2 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 CBZ29339.1 - 3.2e-14 52.7 0.0 3.9e-14 52.5 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Roc PF08477.13 CBZ29339.1 - 8.4e-14 51.8 0.0 1.2e-13 51.4 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase G-alpha PF00503.20 CBZ29339.1 - 2.8e-13 49.8 0.4 5e-09 35.8 0.1 2.2 1 1 1 2 2 2 2 G-protein alpha subunit Ras PF00071.22 CBZ29339.1 - 1.1e-12 47.9 0.0 1.2e-12 47.8 0.0 1.1 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.12 CBZ29339.1 - 2.8e-09 36.7 0.0 3.5e-09 36.4 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 CBZ29339.1 - 3.6e-05 23.8 0.0 5.6e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.18 CBZ29339.1 - 0.0082 15.5 0.0 0.01 15.1 0.0 1.3 1 0 0 1 1 1 1 6-phosphofructo-2-kinase cobW PF02492.19 CBZ29339.1 - 0.03 13.9 0.2 0.23 11.0 0.0 2.0 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.6 CBZ29339.1 - 0.096 12.8 0.1 0.16 12.2 0.1 1.5 1 1 0 1 1 1 0 AAA domain DUF1771 PF08590.10 CBZ29341.1 - 5.3e-17 62.0 6.4 1.1e-16 61.0 6.4 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1771) KH_1 PF00013.29 CBZ29341.1 - 8.6e-09 35.1 0.5 1.6e-08 34.2 0.5 1.5 1 0 0 1 1 1 1 KH domain Smr PF01713.21 CBZ29341.1 - 7e-07 29.5 0.1 2.3e-06 27.9 0.1 1.9 1 0 0 1 1 1 1 Smr domain KH_2 PF07650.17 CBZ29341.1 - 0.0024 17.7 0.6 0.0058 16.4 0.2 1.9 2 0 0 2 2 2 1 KH domain KH_4 PF13083.6 CBZ29341.1 - 0.1 12.5 0.5 0.41 10.5 0.3 2.0 1 1 0 1 1 1 0 KH domain YtxH PF12732.7 CBZ29341.1 - 2 9.0 7.3 0.82 10.3 0.2 2.6 3 0 0 3 3 3 0 YtxH-like protein Maf1 PF09174.10 CBZ29342.1 - 2.2e-27 96.3 0.0 2.9e-27 95.9 0.0 1.1 1 0 0 1 1 1 1 Maf1 regulator Reprolysin_4 PF13583.6 CBZ29342.1 - 0.11 12.1 0.1 0.17 11.5 0.1 1.2 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like PriC PF07445.12 CBZ29343.1 - 0.34 10.8 3.7 0.91 9.4 3.5 1.8 1 1 0 1 1 1 0 Primosomal replication protein priC PTR2 PF00854.21 CBZ29344.1 - 0.048 12.5 3.9 2.2 7.0 0.0 2.7 1 1 1 3 3 3 0 POT family LapA_dom PF06305.11 CBZ29344.1 - 1.2 9.0 4.1 0.5 10.2 0.3 2.2 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain Ribosomal_L12 PF00542.19 CBZ29345.1 - 8e-18 64.6 1.7 1.5e-17 63.7 1.7 1.5 1 0 0 1 1 1 1 Ribosomal protein L7/L12 C-terminal domain Pkinase PF00069.25 CBZ29346.1 - 6e-58 196.3 0.0 1.8e-57 194.8 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ29346.1 - 3.1e-28 98.8 0.0 6.7e-28 97.7 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 CBZ29346.1 - 0.003 16.9 0.0 0.017 14.4 0.0 2.1 2 0 0 2 2 2 1 Kinase-like RIO1 PF01163.22 CBZ29346.1 - 0.017 14.7 0.2 0.081 12.5 0.2 2.2 1 1 0 1 1 1 0 RIO1 family L71 PF02448.15 CBZ29346.1 - 0.047 14.1 0.1 0.13 12.7 0.1 1.7 1 0 0 1 1 1 0 L71 family Pox_ser-thr_kin PF05445.11 CBZ29346.1 - 0.13 11.2 0.1 0.2 10.6 0.1 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Spc42p PF11544.8 CBZ29346.1 - 0.76 9.8 3.0 2.2 8.3 0.4 2.5 2 0 0 2 2 2 0 Spindle pole body component Spc42p Spc7 PF08317.11 CBZ29346.1 - 1.9 7.3 17.8 0.063 12.2 2.1 2.3 2 0 0 2 2 2 0 Spc7 kinetochore protein Exonuc_VII_L PF02601.15 CBZ29346.1 - 4.4 6.8 12.2 17 4.9 12.2 1.8 1 1 0 1 1 1 0 Exonuclease VII, large subunit DivIC PF04977.15 CBZ29346.1 - 7.9 6.3 11.8 1.4 8.7 0.1 3.3 3 0 0 3 3 3 0 Septum formation initiator Aldo_ket_red PF00248.21 CBZ29348.1 - 1.1e-56 192.2 0.0 2e-55 188.1 0.0 1.9 1 1 0 1 1 1 1 Aldo/keto reductase family Clathrin PF00637.20 CBZ29349.1 - 5.4e-10 39.3 1.6 1.8e-09 37.6 0.5 2.3 2 0 0 2 2 2 1 Region in Clathrin and VPS VPS11_C PF12451.8 CBZ29349.1 - 0.016 15.4 0.0 0.031 14.5 0.0 1.5 1 0 0 1 1 1 0 Vacuolar protein sorting protein 11 C terminal DUF2396 PF09654.10 CBZ29349.1 - 0.045 13.9 0.2 0.045 13.9 0.2 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2396) zf-ANAPC11 PF12861.7 CBZ29349.1 - 0.083 13.0 2.9 0.4 10.8 2.9 2.2 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.6 CBZ29349.1 - 0.27 11.3 10.2 0.67 10.0 5.2 3.2 2 0 0 2 2 2 0 RING-type zinc-finger zf-rbx1 PF12678.7 CBZ29349.1 - 0.45 10.8 7.7 1.4 9.2 7.7 1.9 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-RING_5 PF14634.6 CBZ29349.1 - 2.7 8.0 15.6 1.4 9.0 10.6 2.7 2 0 0 2 2 2 0 zinc-RING finger domain zf-RING_2 PF13639.6 CBZ29349.1 - 4.7 7.6 12.7 2.3 8.6 9.0 2.6 2 0 0 2 2 2 0 Ring finger domain Nup54 PF13874.6 CBZ29350.1 - 2.6e-22 79.5 0.1 2.6e-22 79.5 0.1 1.9 3 0 0 3 3 3 1 Nucleoporin complex subunit 54 Nup54_C PF18437.1 CBZ29350.1 - 0.017 15.0 1.0 0.017 15.0 1.0 2.3 2 0 0 2 2 2 0 Nup54 C-terminal interacting domain DUF5586 PF17824.1 CBZ29351.1 - 0.035 13.2 0.1 0.044 12.9 0.1 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5586) DUF4588 PF15251.6 CBZ29352.1 - 0.0065 16.3 0.1 0.013 15.3 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4588) DUF4677 PF15726.5 CBZ29352.1 - 0.045 13.9 0.3 0.066 13.4 0.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4677) Inositol_P PF00459.25 CBZ29353.1 - 4.5e-13 49.3 0.6 3.5e-12 46.4 0.6 1.9 1 1 0 1 1 1 1 Inositol monophosphatase family Ribosomal_L7Ae PF01248.26 CBZ29354.1 - 0.02 14.6 0.2 0.044 13.5 0.2 1.5 1 0 0 1 1 1 0 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family SQS_PSY PF00494.19 CBZ29355.1 - 6.3e-45 153.7 0.0 8.2e-45 153.4 0.0 1.1 1 0 0 1 1 1 1 Squalene/phytoene synthase NUDIX PF00293.28 CBZ29356.1 - 3.5e-14 53.0 0.1 6.2e-14 52.2 0.1 1.4 1 0 0 1 1 1 1 NUDIX domain zf-NADH-PPase PF09297.11 CBZ29356.1 - 1.3e-08 34.4 3.5 2.2e-08 33.6 3.5 1.4 1 0 0 1 1 1 1 NADH pyrophosphatase zinc ribbon domain DZR PF12773.7 CBZ29356.1 - 0.00028 20.8 0.8 0.00057 19.9 0.8 1.4 1 0 0 1 1 1 1 Double zinc ribbon Nudix_N_2 PF14803.6 CBZ29356.1 - 0.0059 16.5 2.3 2.1 8.3 0.1 2.4 2 0 0 2 2 2 2 Nudix N-terminal zinc_ribbon_2 PF13240.6 CBZ29356.1 - 0.0065 16.1 5.8 0.9 9.3 0.7 2.3 2 0 0 2 2 2 2 zinc-ribbon domain OrfB_Zn_ribbon PF07282.11 CBZ29356.1 - 0.012 15.6 0.0 0.024 14.6 0.0 1.4 1 0 0 1 1 1 0 Putative transposase DNA-binding domain PknG_rubred PF16919.5 CBZ29356.1 - 0.014 15.6 0.2 0.028 14.6 0.2 1.4 1 0 0 1 1 1 0 Protein kinase G rubredoxin domain zf-ribbon_3 PF13248.6 CBZ29356.1 - 0.021 14.3 3.2 3 7.4 0.4 2.4 2 0 0 2 2 2 0 zinc-ribbon domain HypA PF01155.19 CBZ29356.1 - 0.023 14.7 0.1 0.12 12.4 0.0 1.9 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Zn-ribbon_8 PF09723.10 CBZ29356.1 - 0.038 14.1 1.4 0.078 13.1 1.4 1.5 1 0 0 1 1 1 0 Zinc ribbon domain NOB1_Zn_bind PF08772.11 CBZ29356.1 - 0.25 11.5 3.6 7.3 6.8 4.0 2.3 1 1 1 2 2 2 0 Nin one binding (NOB1) Zn-ribbon like RecR PF02132.15 CBZ29356.1 - 0.29 10.8 1.4 2.2 7.9 1.4 2.1 1 1 0 1 1 1 0 RecR protein HscB_4_cys PF18256.1 CBZ29356.1 - 0.39 10.6 3.6 0.78 9.6 3.6 1.5 1 0 0 1 1 1 0 Co-chaperone HscB tetracysteine metal binding motif Zn_Tnp_IS1595 PF12760.7 CBZ29356.1 - 2 8.5 4.9 48 4.0 0.9 2.6 1 1 1 2 2 2 0 Transposase zinc-ribbon domain UPF0547 PF10571.9 CBZ29356.1 - 2.6 8.2 8.4 10 6.3 0.4 2.7 3 0 0 3 3 3 0 Uncharacterised protein family UPF0547 Pkinase PF00069.25 CBZ29357.1 - 1.8e-63 214.4 0.0 2.4e-63 214.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ29357.1 - 3.7e-43 147.7 0.0 5.5e-43 147.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CBZ29357.1 - 2.4e-08 33.6 0.0 1.5e-06 27.7 0.0 2.5 3 0 0 3 3 3 1 Kinase-like PH PF00169.29 CBZ29357.1 - 9e-06 26.2 0.0 2.1e-05 25.0 0.0 1.6 1 0 0 1 1 1 1 PH domain Haspin_kinase PF12330.8 CBZ29357.1 - 0.00049 19.2 0.1 0.00069 18.7 0.1 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 CBZ29357.1 - 0.046 13.1 0.1 0.43 9.9 0.1 2.1 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF1636 PF07845.11 CBZ29357.1 - 0.059 13.8 0.3 0.15 12.5 0.3 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1636) Carboxyl_trans PF01039.22 CBZ29358.1 - 2.4e-129 432.2 0.0 3.2e-129 431.8 0.0 1.2 1 0 0 1 1 1 1 Carboxyl transferase domain CPSase_L_D2 PF02786.17 CBZ29358.1 - 1.9e-51 174.5 0.0 4.6e-51 173.3 0.0 1.6 2 0 0 2 2 2 1 Carbamoyl-phosphate synthase L chain, ATP binding domain ACC_central PF08326.12 CBZ29358.1 - 2.9e-50 171.3 0.4 5.9e-49 167.0 0.4 2.3 1 1 0 1 1 1 1 Acetyl-CoA carboxylase, central region Biotin_carb_N PF00289.22 CBZ29358.1 - 5.2e-29 101.0 0.0 4e-28 98.2 0.0 2.4 2 0 0 2 2 2 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 CBZ29358.1 - 2.4e-21 75.8 0.0 2.3e-20 72.7 0.0 2.7 3 0 0 3 3 3 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.22 CBZ29358.1 - 3.1e-07 30.1 0.0 7.6e-07 28.9 0.0 1.6 1 0 0 1 1 1 1 Biotin-requiring enzyme Dala_Dala_lig_C PF07478.13 CBZ29358.1 - 8.9e-07 28.6 0.0 1.8e-06 27.6 0.0 1.4 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 CBZ29358.1 - 0.00027 20.6 0.3 0.00075 19.1 0.1 1.9 2 0 0 2 2 2 1 ATP-grasp domain ATP-grasp_3 PF02655.14 CBZ29358.1 - 0.00052 20.1 0.0 0.0014 18.7 0.0 1.7 1 0 0 1 1 1 1 ATP-grasp domain Biotin_lipoyl_2 PF13533.6 CBZ29358.1 - 0.0018 18.1 0.0 0.0049 16.7 0.0 1.7 1 0 0 1 1 1 1 Biotin-lipoyl like DUF2283 PF10049.9 CBZ29358.1 - 0.16 12.2 0.1 1.1 9.6 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2283) SMK-1 PF04802.15 CBZ29359.1 - 1.5e-08 34.8 0.0 2.3e-08 34.1 0.0 1.3 1 0 0 1 1 1 1 Component of IIS longevity pathway SMK-1 PSII_Pbs27 PF13326.6 CBZ29360.1 - 1.5 9.1 9.5 0.29 11.4 3.4 3.1 2 0 0 2 2 2 0 Photosystem II Pbs27 F_actin_bind PF08919.10 CBZ29362.1 - 0.0058 16.7 9.1 0.5 10.5 0.7 2.7 1 1 1 2 2 2 2 F-actin binding PIN_8 PF18476.1 CBZ29362.1 - 0.023 14.5 5.7 0.054 13.3 5.7 1.5 1 0 0 1 1 1 0 PIN like domain E2R135 PF11570.8 CBZ29362.1 - 0.056 13.7 0.4 0.056 13.7 0.4 2.4 3 0 0 3 3 3 0 Coiled-coil receptor-binding R-domain of colicin E2 Cep57_MT_bd PF06657.13 CBZ29362.1 - 0.74 10.3 10.2 0.36 11.3 5.2 2.6 2 0 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 TMPIT PF07851.13 CBZ29362.1 - 1.4 8.0 3.4 2.3 7.4 3.4 1.4 1 0 0 1 1 1 0 TMPIT-like protein Spc7 PF08317.11 CBZ29362.1 - 1.8 7.4 14.9 0.17 10.7 9.1 2.1 1 1 0 2 2 2 0 Spc7 kinetochore protein CENP-H PF05837.12 CBZ29362.1 - 3.5 8.1 13.7 0.21 12.0 7.6 2.2 2 0 0 2 2 2 0 Centromere protein H (CENP-H) DUF5401 PF17380.2 CBZ29362.1 - 4.5 5.2 19.4 4.1 5.3 18.3 1.4 2 0 0 2 2 2 0 Family of unknown function (DUF5401) TPR_MLP1_2 PF07926.12 CBZ29362.1 - 8.8 6.4 25.9 0.34 11.0 13.0 3.3 2 1 1 3 3 3 0 TPR/MLP1/MLP2-like protein Per1 PF04080.13 CBZ29366.1 - 0.016 15.0 0.0 0.019 14.7 0.0 1.2 1 0 0 1 1 1 0 Per1-like family DUF1515 PF07439.11 CBZ29366.1 - 0.096 12.7 4.5 0.55 10.3 2.3 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1515) Phg_2220_C PF09524.10 CBZ29366.1 - 0.41 10.7 3.3 2.4 8.3 0.1 2.3 1 1 1 2 2 2 0 Conserved phage C-terminus (Phg_2220_C) Cyclase PF04199.13 CBZ29367.1 - 1.3e-15 57.8 0.0 1.8e-15 57.4 0.0 1.2 1 0 0 1 1 1 1 Putative cyclase Zip PF02535.22 CBZ29368.1 - 1e-41 143.2 2.1 1.5e-41 142.8 2.1 1.2 1 0 0 1 1 1 1 ZIP Zinc transporter HPP PF04982.13 CBZ29368.1 - 1.4 9.1 11.4 0.056 13.6 4.0 2.3 2 1 0 2 2 2 0 HPP family Zip PF02535.22 CBZ29369.1 - 1e-41 143.3 0.6 1.5e-41 142.7 0.6 1.3 1 1 0 1 1 1 1 ZIP Zinc transporter Sdh_cyt PF01127.22 CBZ29369.1 - 1.2 9.2 11.3 2.5 8.2 2.1 3.5 3 0 0 3 3 3 0 Succinate dehydrogenase/Fumarate reductase transmembrane subunit HPP PF04982.13 CBZ29369.1 - 1.2 9.3 11.0 0.065 13.4 4.0 2.3 2 1 0 2 2 2 0 HPP family BTB_2 PF02214.22 CBZ29370.1 - 0.00057 20.2 0.0 0.0016 18.7 0.0 1.8 1 1 0 1 1 1 1 BTB/POZ domain Peptidase_M16 PF00675.20 CBZ29371.1 - 9.6e-32 110.0 0.0 1.9e-31 109.1 0.0 1.5 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_M PF16187.5 CBZ29371.1 - 4.4e-29 101.7 0.0 2.6e-25 89.3 0.0 2.4 3 0 0 3 3 3 2 Middle or third domain of peptidase_M16 Peptidase_M16_C PF05193.21 CBZ29371.1 - 1.4e-12 48.0 0.0 5.2e-08 33.1 0.0 2.7 2 0 0 2 2 2 2 Peptidase M16 inactive domain DnaJ PF00226.31 CBZ29372.1 - 8.6e-17 61.0 0.1 1.4e-16 60.4 0.1 1.3 1 0 0 1 1 1 1 DnaJ domain Autophagy_act_C PF03987.15 CBZ29373.1 - 0.14 12.8 0.1 0.33 11.6 0.1 1.7 1 1 0 1 1 1 0 Autophagocytosis associated protein, active-site domain SUV3_C PF12513.8 CBZ29374.1 - 0.12 12.3 0.2 0.12 12.3 0.2 2.9 2 0 0 2 2 2 0 Mitochondrial degradasome RNA helicase subunit C terminal PEMT PF04191.13 CBZ29375.1 - 2.2e-52 175.9 11.1 7.4e-30 103.5 0.9 2.8 2 0 0 2 2 2 2 Phospholipid methyltransferase CPSase_L_D2 PF02786.17 CBZ29376.1 - 1e-62 211.4 0.0 1.7e-62 210.7 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.22 CBZ29376.1 - 7.9e-44 148.7 0.1 2e-43 147.4 0.1 1.7 2 0 0 2 2 1 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 CBZ29376.1 - 3e-34 117.4 0.0 6.7e-34 116.2 0.0 1.6 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.22 CBZ29376.1 - 7.6e-15 54.5 2.1 1.5e-14 53.6 2.1 1.5 1 0 0 1 1 1 1 Biotin-requiring enzyme Dala_Dala_lig_C PF07478.13 CBZ29376.1 - 8e-11 41.9 0.0 2.1e-10 40.5 0.0 1.6 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 CBZ29376.1 - 1.3e-09 37.9 0.1 2.3e-09 37.0 0.1 1.4 1 0 0 1 1 1 1 ATP-grasp domain Biotin_lipoyl_2 PF13533.6 CBZ29376.1 - 0.00012 21.8 0.8 0.00058 19.6 0.1 2.2 1 1 1 2 2 2 1 Biotin-lipoyl like ATP-grasp_3 PF02655.14 CBZ29376.1 - 0.0097 16.0 0.0 0.029 14.4 0.0 1.9 1 1 0 1 1 1 1 ATP-grasp domain ATPgrasp_ST PF14397.6 CBZ29376.1 - 0.026 13.8 0.0 0.076 12.3 0.0 1.6 2 0 0 2 2 2 0 Sugar-transfer associated ATP-grasp HlyD_3 PF13437.6 CBZ29376.1 - 0.22 12.2 0.3 32 5.3 0.0 2.9 3 0 0 3 3 3 0 HlyD family secretion protein RnfC_N PF13375.6 CBZ29376.1 - 0.26 11.2 1.1 1.1 9.2 0.5 2.3 2 0 0 2 2 2 0 RnfC Barrel sandwich hybrid domain FAD_binding_3 PF01494.19 CBZ29377.1 - 0.048 12.9 0.0 0.089 12.0 0.0 1.4 1 0 0 1 1 1 0 FAD binding domain Robl_LC7 PF03259.17 CBZ29378.1 - 2.1e-08 33.8 0.0 2.9e-08 33.4 0.0 1.1 1 0 0 1 1 1 1 Roadblock/LC7 domain ARL2_Bind_BART PF11527.8 CBZ29379.1 - 0.06 13.5 0.5 0.15 12.2 0.1 1.9 2 0 0 2 2 2 0 The ARF-like 2 binding protein BART YabA PF06156.13 CBZ29379.1 - 4.4 8.0 6.9 25 5.6 0.3 3.9 2 1 1 3 3 3 0 Initiation control protein YabA Fib_alpha PF08702.10 CBZ29379.1 - 4.4 7.5 13.5 5.7 7.1 1.4 4.2 4 0 0 4 4 4 0 Fibrinogen alpha/beta chain family Pkinase PF00069.25 CBZ29380.1 - 8e-61 205.7 0.0 1.1e-60 205.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ29380.1 - 3.6e-41 141.2 0.0 5.1e-41 140.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase PH PF00169.29 CBZ29380.1 - 1.6e-12 47.8 0.1 3.4e-12 46.8 0.1 1.5 1 0 0 1 1 1 1 PH domain PH_9 PF15410.6 CBZ29380.1 - 2.6e-08 34.2 0.3 7.4e-07 29.6 0.3 2.5 1 1 0 1 1 1 1 Pleckstrin homology domain Kinase-like PF14531.6 CBZ29380.1 - 3.2e-07 29.9 0.0 5.1e-07 29.3 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 CBZ29380.1 - 0.011 14.6 0.2 0.097 11.4 0.0 2.0 2 0 0 2 2 2 0 Fungal protein kinase PH_11 PF15413.6 CBZ29380.1 - 0.2 12.1 2.7 18 5.8 2.7 2.7 1 1 0 1 1 1 0 Pleckstrin homology domain MFS_1 PF07690.16 CBZ29381.1 - 1.2e-23 83.6 35.0 2.2e-20 72.9 21.9 2.2 2 0 0 2 2 2 2 Major Facilitator Superfamily Nodulin-like PF06813.13 CBZ29381.1 - 4.1e-12 46.1 8.3 4.1e-12 46.1 8.3 2.7 3 1 0 3 3 3 1 Nodulin-like TssO PF17561.2 CBZ29381.1 - 0.039 14.1 5.3 0.051 13.7 0.1 3.0 3 0 0 3 3 3 0 Type VI secretion system, TssO Arm_APC_u3 PF16629.5 CBZ29381.1 - 0.091 12.3 0.2 1 8.9 0.0 2.1 2 0 0 2 2 2 0 Armadillo-associated region on APC UPF0242 PF06785.11 CBZ29381.1 - 3.9 7.5 8.2 0.51 10.4 1.2 3.0 4 0 0 4 4 4 0 Uncharacterised protein family (UPF0242) N-terminus CENP-T_C PF15511.6 CBZ29382.1 - 1e-06 28.8 0.1 1.5e-06 28.3 0.1 1.3 1 1 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CBFD_NFYB_HMF PF00808.23 CBZ29382.1 - 9.5e-05 22.6 0.8 0.00011 22.5 0.1 1.4 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TAF PF02969.17 CBZ29382.1 - 0.0002 21.5 0.2 0.00032 20.8 0.2 1.3 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) Bromo_TP PF07524.13 CBZ29382.1 - 0.00061 19.7 0.0 0.00077 19.4 0.0 1.2 1 0 0 1 1 1 1 Bromodomain associated Histone PF00125.24 CBZ29382.1 - 0.0034 17.7 2.2 0.0064 16.9 2.2 1.5 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID-31kDa PF02291.15 CBZ29382.1 - 0.011 15.8 0.0 0.014 15.4 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit PCP_red PF08369.10 CBZ29382.1 - 0.18 12.0 1.6 0.46 10.7 0.1 2.3 2 1 0 2 2 2 0 Proto-chlorophyllide reductase 57 kD subunit Galactosyl_T PF01762.21 CBZ29383.1 - 0.00044 20.1 1.1 0.00087 19.2 0.0 2.0 3 0 0 3 3 3 1 Galactosyltransferase DUF4245 PF14030.6 CBZ29385.1 - 0.18 11.8 1.5 0.46 10.5 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4245) RasGEF_N_2 PF14663.6 CBZ29385.1 - 0.24 11.8 4.0 0.12 12.8 0.9 2.2 2 1 0 2 2 2 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain TrbM PF07424.11 CBZ29385.1 - 0.58 10.1 6.8 2 8.3 1.4 2.7 1 1 2 3 3 3 0 TrbM Torus PF16131.5 CBZ29386.1 - 0.22 12.2 1.7 1.3 9.7 0.7 2.5 2 1 0 2 2 2 0 Torus domain Torus PF16131.5 CBZ29387.1 - 0.029 15.0 1.2 0.24 12.1 0.0 2.5 3 0 0 3 3 3 0 Torus domain WD40 PF00400.32 CBZ29388.1 - 3.1e-19 69.0 3.4 0.025 15.4 0.0 6.2 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBZ29388.1 - 6.6e-06 26.3 0.2 1.1 9.7 0.0 3.7 3 1 0 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain SNARE PF05739.19 CBZ29390.1 - 1.1e-11 44.5 2.1 8.5e-11 41.7 0.0 2.7 3 0 0 3 3 3 1 SNARE domain Syntaxin PF00804.25 CBZ29390.1 - 0.00016 21.4 13.7 0.0024 17.6 13.7 2.4 1 1 0 1 1 1 1 Syntaxin DUF2935 PF11155.8 CBZ29390.1 - 0.017 15.5 0.1 0.6 10.5 0.1 2.6 1 1 0 1 1 1 0 Domain of unknown function (DUF2935) DUF4208 PF13907.6 CBZ29390.1 - 0.042 14.3 1.0 5 7.6 0.1 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4208) DUF445 PF04286.12 CBZ29390.1 - 0.045 13.6 4.6 0.15 11.8 4.5 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF445) SF-assemblin PF06705.11 CBZ29390.1 - 0.12 11.7 5.3 0.52 9.6 0.8 2.2 1 1 1 2 2 2 0 SF-assemblin/beta giardin Fib_alpha PF08702.10 CBZ29390.1 - 1.2 9.3 8.6 3.6 7.8 1.1 2.3 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family DUF16 PF01519.16 CBZ29390.1 - 2.1 8.9 9.6 0.52 10.8 1.3 2.9 1 1 1 2 2 2 0 Protein of unknown function DUF16 OmpH PF03938.14 CBZ29390.1 - 3.5 8.0 15.1 4.4 7.7 10.4 2.7 2 1 0 2 2 2 0 Outer membrane protein (OmpH-like) NMT PF01233.19 CBZ29391.1 - 1.6e-67 226.3 0.0 2.7e-67 225.6 0.0 1.4 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain NMT_C PF02799.15 CBZ29391.1 - 4.9e-64 215.7 0.7 7.1e-64 215.2 0.1 1.5 2 0 0 2 2 2 1 Myristoyl-CoA:protein N-myristoyltransferase, C-terminal domain Acetyltransf_1 PF00583.25 CBZ29391.1 - 0.058 13.6 0.0 0.13 12.5 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family Acetyltransf_CG PF14542.6 CBZ29391.1 - 0.14 12.3 0.0 0.3 11.3 0.0 1.5 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase TMEM239 PF15841.5 CBZ29392.1 - 0.039 13.8 0.4 0.074 13.0 0.4 1.4 1 0 0 1 1 1 0 Transmembrane protein 239 family NIF PF03031.18 CBZ29393.1 - 7.7e-26 90.7 0.0 8.5e-26 90.6 0.0 1.1 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Mito_carr PF00153.27 CBZ29394.1 - 4.8e-38 129.0 2.7 5e-14 52.0 0.0 4.3 3 1 1 4 4 4 4 Mitochondrial carrier protein Pkinase PF00069.25 CBZ29395.1 - 3.2e-57 193.9 0.0 4.2e-57 193.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ29395.1 - 1.1e-27 96.9 0.0 1.6e-27 96.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CBZ29395.1 - 2.3e-05 23.4 0.0 3.7e-05 22.7 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 CBZ29395.1 - 0.0003 20.2 0.0 0.00047 19.6 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 CBZ29395.1 - 0.0013 18.1 0.0 0.0027 17.1 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 CBZ29395.1 - 0.019 13.9 0.0 0.03 13.3 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain APH PF01636.23 CBZ29395.1 - 0.042 13.8 0.0 0.075 12.9 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Arm PF00514.23 CBZ29397.1 - 3.5e-42 141.2 22.3 1.1e-07 31.6 0.0 16.8 16 1 0 16 16 16 10 Armadillo/beta-catenin-like repeat Arm_2 PF04826.13 CBZ29397.1 - 3.2e-07 30.1 0.4 0.19 11.1 0.0 5.3 5 1 0 6 6 6 2 Armadillo-like HEAT_EZ PF13513.6 CBZ29397.1 - 0.0044 17.5 10.9 52 4.5 0.0 7.6 6 3 1 7 7 7 0 HEAT-like repeat Atx10homo_assoc PF09759.9 CBZ29397.1 - 0.0064 16.5 1.3 7.3 6.7 0.0 5.2 6 1 1 7 7 7 1 Spinocerebellar ataxia type 10 protein domain WAPL PF07814.13 CBZ29397.1 - 0.056 12.2 1.7 2 7.1 0.0 3.9 3 2 0 3 3 3 0 Wings apart-like protein regulation of heterochromatin DUF383 PF04063.14 CBZ29397.1 - 0.059 13.0 0.0 60 3.2 0.0 3.7 3 0 0 3 3 3 0 Domain of unknown function (DUF383) HEAT PF02985.22 CBZ29397.1 - 0.15 12.4 10.4 32 5.1 0.5 6.4 5 1 0 5 5 5 0 HEAT repeat Spc7 PF08317.11 CBZ29397.1 - 0.35 9.7 4.6 0.55 9.1 4.6 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein TMF_DNA_bd PF12329.8 CBZ29397.1 - 1.1 9.3 7.3 2.5 8.2 7.3 1.5 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding Utp14 PF04615.13 CBZ29398.1 - 7.2e-115 385.3 43.8 7.2e-115 385.3 43.8 1.4 1 1 0 1 1 1 1 Utp14 protein LRR_9 PF14580.6 CBZ29401.1 - 2.3e-20 72.8 1.7 6.2e-20 71.4 1.7 1.7 1 1 0 1 1 1 1 Leucine-rich repeat LRR_4 PF12799.7 CBZ29401.1 - 0.014 15.8 0.4 10 6.7 0.0 3.6 2 2 1 3 3 3 0 Leucine Rich repeats (2 copies) CCDC-167 PF15188.6 CBZ29401.1 - 0.029 14.7 6.1 0.059 13.7 3.6 2.3 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 167 Pex19 PF04614.12 CBZ29401.1 - 0.061 13.1 1.4 0.087 12.6 1.4 1.1 1 0 0 1 1 1 0 Pex19 protein family Csm1_N PF18504.1 CBZ29401.1 - 0.45 10.9 5.6 18 5.8 1.8 3.3 2 1 1 3 3 3 0 Csm1 N-terminal domain Rtf2 PF04641.12 CBZ29401.1 - 0.8 9.0 0.0 0.8 9.0 0.0 2.6 1 1 2 3 3 3 0 Rtf2 RING-finger DUF4404 PF14357.6 CBZ29401.1 - 4.9 7.9 7.3 1.4 9.6 3.7 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4404) DUF4407 PF14362.6 CBZ29401.1 - 6.7 6.0 10.8 9.4 5.5 10.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) HSP70 PF00012.20 CBZ29403.1 - 2.5e-07 29.3 0.0 0.00085 17.6 0.0 3.0 4 0 0 4 4 4 2 Hsp70 protein LMWPc PF01451.21 CBZ29404.1 - 0.11 12.8 0.1 18 5.7 0.0 2.5 2 0 0 2 2 2 0 Low molecular weight phosphotyrosine protein phosphatase Fib_alpha PF08702.10 CBZ29404.1 - 0.14 12.3 3.9 5.3 7.2 0.1 3.5 4 0 0 4 4 4 0 Fibrinogen alpha/beta chain family Baculo_PEP_C PF04513.12 CBZ29404.1 - 0.48 10.5 5.4 17 5.4 0.1 3.5 3 1 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Filament PF00038.21 CBZ29404.1 - 0.68 9.5 10.9 1.2 8.6 0.1 2.9 2 1 1 3 3 3 0 Intermediate filament protein Rtt106 PF08512.12 CBZ29405.1 - 1.3e-11 44.7 0.0 1.6e-09 38.1 0.0 2.9 3 0 0 3 3 3 1 Histone chaperone Rttp106-like SSrecog PF03531.14 CBZ29405.1 - 0.0003 20.6 0.0 0.0011 18.9 0.0 2.1 1 1 0 1 1 1 1 Structure-specific recognition protein (SSRP1) YL1 PF05764.13 CBZ29405.1 - 0.0042 17.3 36.2 0.0061 16.7 36.2 1.2 1 0 0 1 1 1 1 YL1 nuclear protein SDA1 PF05285.12 CBZ29405.1 - 0.76 9.1 37.8 1 8.7 37.8 1.1 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.12 CBZ29405.1 - 0.96 7.6 38.1 1.2 7.3 38.1 1.1 1 0 0 1 1 1 0 Nop14-like family Presenilin PF01080.17 CBZ29405.1 - 4.1 6.1 15.9 5.3 5.7 15.9 1.1 1 0 0 1 1 1 0 Presenilin CDC45 PF02724.14 CBZ29405.1 - 4.7 5.4 37.4 6.3 5.0 37.4 1.1 1 0 0 1 1 1 0 CDC45-like protein Apt1 PF10351.9 CBZ29405.1 - 7.8 5.2 20.3 10 4.8 20.3 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain MPM1 PF17234.2 CBZ29406.1 - 0.2 11.9 4.3 0.57 10.4 4.3 1.7 1 0 0 1 1 1 0 Mitochondrial peculiar membrane protein 1 Peroxin-3 PF04882.12 CBZ29406.1 - 2.3 7.1 12.5 6.3 5.7 0.5 2.5 2 0 0 2 2 2 0 Peroxin-3 Dynein_light PF01221.18 CBZ29407.1 - 6.7e-41 138.5 0.9 7.5e-41 138.4 0.9 1.0 1 0 0 1 1 1 1 Dynein light chain type 1 Peptidase_C3 PF00548.20 CBZ29407.1 - 0.018 15.0 0.0 0.021 14.7 0.0 1.1 1 0 0 1 1 1 0 3C cysteine protease (picornain 3C) Imm48 PF15574.6 CBZ29407.1 - 0.065 13.0 0.1 0.087 12.6 0.1 1.1 1 0 0 1 1 1 0 Immunity protein 48 Ectatomin PF06457.11 CBZ29407.1 - 0.067 13.1 0.0 0.12 12.3 0.0 1.4 1 0 0 1 1 1 0 Ectatomin LRR_4 PF12799.7 CBZ29408.1 - 1.6e-06 28.3 1.0 0.0081 16.6 0.1 3.8 3 0 0 3 3 3 2 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 CBZ29408.1 - 0.00062 19.6 0.5 15 6.0 0.0 4.5 4 0 0 4 4 4 1 Leucine Rich repeat IFT57 PF10498.9 CBZ29408.1 - 0.013 14.5 2.0 0.094 11.7 2.9 1.9 2 0 0 2 2 2 0 Intra-flagellar transport protein 57 LRR_8 PF13855.6 CBZ29408.1 - 0.097 12.5 3.2 3.7 7.4 0.0 3.2 3 0 0 3 3 3 0 Leucine rich repeat AAA_13 PF13166.6 CBZ29408.1 - 0.1 11.2 2.1 0.19 10.4 2.1 1.4 1 0 0 1 1 1 0 AAA domain DUF4200 PF13863.6 CBZ29408.1 - 0.19 12.1 13.8 1.5 9.2 5.6 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) Spc7 PF08317.11 CBZ29408.1 - 0.62 8.9 9.5 1.4 7.8 9.5 1.6 1 0 0 1 1 1 0 Spc7 kinetochore protein Pkinase PF00069.25 CBZ29410.1 - 4.9e-67 226.1 0.0 6.9e-67 225.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ29410.1 - 2.1e-50 171.4 0.0 3e-50 170.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CBZ29410.1 - 2.6e-05 23.7 0.0 7.8e-05 22.1 0.0 1.7 2 0 0 2 2 2 1 Kinase-like RIO1 PF01163.22 CBZ29410.1 - 0.019 14.5 0.2 0.048 13.3 0.2 1.5 1 0 0 1 1 1 0 RIO1 family Big_9 PF17963.1 CBZ29411.1 - 0.0033 18.1 0.2 0.042 14.6 0.2 3.0 1 0 0 1 1 1 1 Bacterial Ig domain B9-C2 PF07162.11 CBZ29412.1 - 5.8e-34 117.7 0.0 7.2e-34 117.4 0.0 1.1 1 0 0 1 1 1 1 Ciliary basal body-associated, B9 protein LRR_8 PF13855.6 CBZ29414.1 - 2.4e-12 46.4 8.2 3.2e-06 26.8 1.2 5.3 4 1 1 5 5 5 5 Leucine rich repeat LRR_4 PF12799.7 CBZ29414.1 - 1.3e-08 35.0 8.4 0.085 13.3 0.7 4.6 2 2 5 7 7 7 6 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 CBZ29414.1 - 0.0024 17.8 8.5 4.7 7.5 0.7 6.2 7 0 0 7 7 7 1 Leucine Rich repeat LRR_1 PF00560.33 CBZ29414.1 - 0.11 13.1 7.3 14 6.7 0.3 5.8 6 1 0 6 6 6 0 Leucine Rich Repeat LRR_9 PF14580.6 CBZ29414.1 - 0.2 11.2 0.1 6.5 6.2 0.0 2.5 2 1 0 2 2 2 0 Leucine-rich repeat TPR_19 PF14559.6 CBZ29415.1 - 1.4e-05 25.5 21.4 0.014 15.8 0.6 7.7 8 2 1 9 9 8 2 Tetratricopeptide repeat Coatomer_WDAD PF04053.14 CBZ29415.1 - 3.3e-05 23.1 3.6 0.028 13.5 0.0 4.1 3 1 1 4 4 4 2 Coatomer WD associated region Clathrin PF00637.20 CBZ29415.1 - 0.00017 21.5 0.3 14 5.6 0.0 5.2 4 2 1 5 5 5 0 Region in Clathrin and VPS TPR_7 PF13176.6 CBZ29415.1 - 0.0016 18.3 18.7 1.7 8.8 0.7 7.5 8 1 1 9 9 8 2 Tetratricopeptide repeat ANAPC4_WD40 PF12894.7 CBZ29415.1 - 0.0074 16.6 0.2 4 7.8 0.0 3.8 2 1 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain TPR_16 PF13432.6 CBZ29415.1 - 0.015 16.0 1.4 0.015 16.0 1.4 7.1 8 0 0 8 8 7 0 Tetratricopeptide repeat TPR_14 PF13428.6 CBZ29415.1 - 0.044 14.6 28.9 12 7.1 2.1 10.4 9 2 2 11 11 9 0 Tetratricopeptide repeat Nucleoporin_N PF08801.11 CBZ29415.1 - 0.075 11.8 0.0 0.13 11.0 0.0 1.3 1 0 0 1 1 1 0 Nup133 N terminal like MIT PF04212.18 CBZ29415.1 - 0.49 10.5 14.9 10 6.3 0.2 5.9 6 0 0 6 6 6 0 MIT (microtubule interacting and transport) domain TPR_2 PF07719.17 CBZ29415.1 - 0.52 10.6 31.2 3.6 7.9 3.4 9.3 9 1 0 9 9 9 0 Tetratricopeptide repeat TPR_1 PF00515.28 CBZ29415.1 - 0.53 10.2 19.3 8.1 6.5 0.2 6.8 6 1 0 6 6 6 0 Tetratricopeptide repeat TPR_12 PF13424.6 CBZ29415.1 - 1 9.7 26.6 6.7 7.1 1.0 7.5 8 0 0 8 8 7 0 Tetratricopeptide repeat TPR_8 PF13181.6 CBZ29415.1 - 1.8 9.0 16.7 7.1 7.1 0.6 7.2 8 1 1 9 9 8 0 Tetratricopeptide repeat RPN7 PF10602.9 CBZ29415.1 - 6.3 6.5 10.4 3.4 7.3 0.0 4.6 5 1 1 6 6 6 0 26S proteasome subunit RPN7 ARL2_Bind_BART PF11527.8 CBZ29418.1 - 0.016 15.3 0.0 0.072 13.2 0.0 2.0 1 1 0 1 1 1 0 The ARF-like 2 binding protein BART RHD3 PF05879.12 CBZ29421.1 - 3.5e-105 352.8 0.0 5.8e-93 312.4 0.0 3.1 3 0 0 3 3 3 3 Root hair defective 3 GTP-binding protein (RHD3) Dynamin_N PF00350.23 CBZ29421.1 - 2.3e-05 24.5 0.0 4.8e-05 23.5 0.0 1.5 1 0 0 1 1 1 1 Dynamin family AAA_28 PF13521.6 CBZ29421.1 - 0.00033 20.9 0.1 0.001 19.3 0.1 1.9 1 0 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.23 CBZ29421.1 - 0.0088 16.1 0.2 0.029 14.4 0.1 2.0 2 0 0 2 2 2 1 50S ribosome-binding GTPase JAB PF01398.21 CBZ29423.1 - 3.2e-25 88.4 0.0 3.4e-24 85.1 0.0 2.1 2 0 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.6 CBZ29423.1 - 2e-17 63.6 0.6 4.3e-17 62.5 0.6 1.6 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function ASL_C PF08328.11 CBZ29423.1 - 0.024 14.7 0.8 3.5 7.8 0.2 2.4 2 0 0 2 2 2 0 Adenylosuccinate lyase C-terminal DEAD PF00270.29 CBZ29424.1 - 1.4e-46 158.4 0.0 2.3e-46 157.7 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CBZ29424.1 - 1.4e-32 112.3 0.0 4.1e-31 107.6 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ERCC3_RAD25_C PF16203.5 CBZ29424.1 - 0.0023 17.2 0.0 0.0036 16.5 0.0 1.2 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase AAA_22 PF13401.6 CBZ29424.1 - 0.055 13.7 0.0 0.52 10.6 0.0 2.2 1 1 0 1 1 1 0 AAA domain GRIM-19 PF06212.12 CBZ29424.1 - 0.13 12.2 0.0 0.28 11.1 0.0 1.5 1 0 0 1 1 1 0 GRIM-19 protein TPR_19 PF14559.6 CBZ29425.1 - 0.0003 21.3 11.4 0.46 11.0 1.6 4.4 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.6 CBZ29425.1 - 0.024 14.8 5.7 2.3 8.7 0.0 5.1 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_2 PF07719.17 CBZ29425.1 - 0.18 12.0 28.3 2.5 8.5 0.0 9.0 9 0 0 9 9 9 0 Tetratricopeptide repeat TPR_12 PF13424.6 CBZ29425.1 - 0.43 10.9 28.9 0.53 10.6 0.1 6.7 6 1 1 8 8 8 0 Tetratricopeptide repeat TPR_1 PF00515.28 CBZ29425.1 - 1 9.3 11.1 5.7 6.9 1.3 4.7 4 0 0 4 4 4 0 Tetratricopeptide repeat Kinesin PF00225.23 CBZ29426.1 - 7.2e-34 117.2 0.0 9.7e-34 116.8 0.0 1.1 1 0 0 1 1 1 1 Kinesin motor domain MORN PF02493.20 CBZ29426.1 - 4.9e-18 63.9 32.7 0.00022 20.9 0.0 7.5 7 0 0 7 7 7 5 MORN repeat Microtub_bd PF16796.5 CBZ29426.1 - 2.6e-10 40.4 0.0 4.5e-10 39.7 0.0 1.4 1 0 0 1 1 1 1 Microtubule binding Ribosomal_L22 PF00237.19 CBZ29427.1 - 4.6e-32 110.3 0.4 5.6e-32 110.0 0.4 1.1 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e DUF1279 PF06916.13 CBZ29428.1 - 3.9e-07 30.5 0.0 6.2e-07 29.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1279) WW PF00397.26 CBZ29428.1 - 0.00024 21.1 0.5 0.00061 19.8 0.5 1.7 1 0 0 1 1 1 1 WW domain Ribosomal_S5_C PF03719.15 CBZ29429.1 - 4.7e-25 86.8 0.0 7.7e-25 86.1 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain Ribosomal_S5 PF00333.20 CBZ29429.1 - 1.8e-21 75.9 0.3 3.7e-21 74.9 0.3 1.6 1 0 0 1 1 1 1 Ribosomal protein S5, N-terminal domain Phage_tail_NK PF16532.5 CBZ29429.1 - 0.21 11.2 0.0 0.33 10.6 0.0 1.2 1 0 0 1 1 1 0 Sf6-type phage tail needle knob or tip of some Caudovirales FoP_duplication PF13865.6 CBZ29429.1 - 0.32 11.6 6.9 0.66 10.6 6.9 1.5 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 Aldo_ket_red PF00248.21 CBZ29430.1 - 1.1e-56 192.2 0.0 9.2e-55 185.9 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family LRR_6 PF13516.6 CBZ29431.1 - 5.3e-06 26.1 20.8 0.75 10.0 0.0 9.3 10 0 0 10 10 10 2 Leucine Rich repeat FmiP_Thoc5 PF09766.9 CBZ29431.1 - 0.0058 16.0 1.3 0.01 15.2 1.3 1.3 1 0 0 1 1 1 1 Fms-interacting protein/Thoc5 Peptidase_S49 PF01343.18 CBZ29431.1 - 0.17 11.9 0.0 0.73 9.8 0.1 2.0 2 0 0 2 2 2 0 Peptidase family S49 RNA_polI_A34 PF08208.11 CBZ29431.1 - 3.6 7.6 14.2 11 6.1 14.0 1.8 2 0 0 2 2 2 0 DNA-directed RNA polymerase I subunit RPA34.5 IFT57 PF10498.9 CBZ29431.1 - 4.9 6.0 14.5 9.8 5.0 14.5 1.4 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 CDC45 PF02724.14 CBZ29431.1 - 9.8 4.3 27.9 0.064 11.5 19.5 1.5 2 0 0 2 2 2 0 CDC45-like protein Rtf2 PF04641.12 CBZ29432.1 - 4.1e-23 82.1 0.3 3e-22 79.3 0.3 1.9 1 1 0 1 1 1 1 Rtf2 RING-finger zf-Nse PF11789.8 CBZ29432.1 - 0.0021 17.9 0.0 2.3 8.1 0.0 2.5 2 1 0 2 2 2 2 Zinc-finger of the MIZ type in Nse subunit zf-NOSIP PF15906.5 CBZ29432.1 - 0.018 15.2 0.0 0.031 14.4 0.0 1.4 1 0 0 1 1 1 0 Zinc-finger of nitric oxide synthase-interacting protein Ras PF00071.22 CBZ29435.1 - 2.4e-56 189.8 0.1 2.8e-56 189.6 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CBZ29435.1 - 1.1e-35 122.4 0.0 1.6e-35 121.9 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CBZ29435.1 - 1.5e-14 53.8 0.0 1.8e-14 53.6 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 CBZ29435.1 - 2.5e-07 30.4 0.1 3.1e-06 26.9 0.1 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 CBZ29435.1 - 1.3e-05 25.3 0.0 2.2e-05 24.5 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 CBZ29435.1 - 1.7e-05 24.3 0.0 2e-05 24.1 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 CBZ29435.1 - 0.00024 21.0 0.0 0.038 13.9 0.0 2.2 2 0 0 2 2 2 1 RsgA GTPase Septin PF00735.18 CBZ29435.1 - 0.0011 18.3 0.0 0.0017 17.7 0.0 1.2 1 0 0 1 1 1 1 Septin PduV-EutP PF10662.9 CBZ29435.1 - 0.0052 16.5 0.1 0.015 15.1 0.0 1.7 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation AAA_22 PF13401.6 CBZ29435.1 - 0.019 15.2 0.0 0.089 13.1 0.0 1.9 1 1 0 2 2 2 0 AAA domain NACHT PF05729.12 CBZ29435.1 - 0.021 14.8 0.0 0.038 13.9 0.0 1.4 1 0 0 1 1 1 0 NACHT domain AAA_16 PF13191.6 CBZ29435.1 - 0.068 13.6 0.1 0.097 13.0 0.1 1.7 1 1 0 1 1 1 0 AAA ATPase domain TniB PF05621.11 CBZ29435.1 - 0.07 12.5 0.0 0.11 11.8 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein YwhD PF08741.10 CBZ29435.1 - 0.08 12.6 0.0 0.1 12.3 0.0 1.3 1 0 0 1 1 1 0 YwhD family DAP3 PF10236.9 CBZ29435.1 - 0.11 11.6 0.0 0.41 9.8 0.0 1.8 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 AAA_7 PF12775.7 CBZ29435.1 - 0.15 11.6 0.0 0.24 10.9 0.0 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region CDC50 PF03381.15 CBZ29437.1 - 1.9e-49 168.7 0.0 2.4e-49 168.4 0.0 1.1 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family COX7C PF02935.16 CBZ29437.1 - 0.022 15.0 0.8 0.85 9.9 0.5 2.6 2 0 0 2 2 2 0 Cytochrome c oxidase subunit VIIc Neurensin PF14927.6 CBZ29437.1 - 0.19 11.5 0.2 7 6.4 0.0 2.8 3 0 0 3 3 3 0 Neurensin Profilin PF00235.19 CBZ29438.1 - 1.1e-41 142.1 0.4 1.3e-41 141.8 0.4 1.1 1 0 0 1 1 1 1 Profilin TauE PF01925.19 CBZ29440.1 - 1e-18 67.9 31.2 4.5e-14 52.7 0.1 2.9 3 0 0 3 3 3 2 Sulfite exporter TauE/SafE Ctr PF04145.15 CBZ29440.1 - 0.082 13.5 0.0 0.26 11.9 0.0 1.8 1 0 0 1 1 1 0 Ctr copper transporter family MTCP1 PF08991.10 CBZ29441.1 - 0.00027 21.1 3.8 0.00027 21.1 3.8 2.1 2 1 0 2 2 2 1 Mature-T-Cell Proliferation I type CHCH PF06747.13 CBZ29441.1 - 0.0077 16.3 12.3 0.14 12.3 2.5 2.5 2 0 0 2 2 2 2 CHCH domain Cmc1 PF08583.10 CBZ29441.1 - 0.26 11.3 11.9 0.71 9.9 0.3 2.8 2 1 1 3 3 3 0 Cytochrome c oxidase biogenesis protein Cmc1 like CX9C PF16860.5 CBZ29441.1 - 0.39 10.8 0.2 0.39 10.8 0.2 2.8 3 1 0 3 3 3 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, zf-C3HC4_3 PF13920.6 CBZ29442.1 - 3.5e-05 23.6 17.9 5.8e-05 22.9 17.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) SKG6 PF08693.10 CBZ29442.1 - 0.85 9.1 3.0 1.4 8.4 3.0 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain DEAD PF00270.29 CBZ29443.1 - 3.1e-34 118.3 0.1 6.4e-34 117.2 0.1 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CBZ29443.1 - 3.7e-27 94.9 0.1 1.5e-26 92.9 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 CBZ29443.1 - 1.1e-06 28.8 0.0 2.4e-06 27.6 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CMS1 PF14617.6 CBZ29443.1 - 0.27 10.5 2.6 0.28 10.5 0.0 2.3 3 0 0 3 3 3 0 U3-containing 90S pre-ribosomal complex subunit YL1 PF05764.13 CBZ29444.1 - 0.0056 16.8 8.3 0.0056 16.8 8.3 1.8 2 0 0 2 2 2 1 YL1 nuclear protein PBP1_TM PF14812.6 CBZ29444.1 - 0.72 10.3 11.8 2.5 8.5 11.8 1.9 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Nop14 PF04147.12 CBZ29444.1 - 1.2 7.3 6.6 2.2 6.4 6.6 1.4 1 0 0 1 1 1 0 Nop14-like family RXT2_N PF08595.11 CBZ29444.1 - 1.2 9.1 4.2 3.4 7.7 4.2 1.7 1 0 0 1 1 1 0 RXT2-like, N-terminal NOA36 PF06524.12 CBZ29444.1 - 4.9 6.4 10.2 8.2 5.7 10.2 1.2 1 0 0 1 1 1 0 NOA36 protein FAM176 PF14851.6 CBZ29444.1 - 9.4 5.9 7.4 34 4.1 7.4 2.0 1 1 0 1 1 1 0 FAM176 family DnaJ PF00226.31 CBZ29445.1 - 9.2e-10 38.5 0.0 2.5e-09 37.1 0.0 1.7 1 0 0 1 1 1 1 DnaJ domain TRPM_tetra PF16519.5 CBZ29446.1 - 0.0038 17.3 0.6 0.012 15.7 0.6 1.9 1 0 0 1 1 1 1 Tetramerisation domain of TRPM WD40 PF00400.32 CBZ29447.1 - 4.6e-10 39.9 0.9 0.00075 20.3 0.3 4.1 3 0 0 3 3 3 2 WD domain, G-beta repeat Ge1_WD40 PF16529.5 CBZ29447.1 - 0.051 12.5 0.1 22 3.8 0.0 3.2 2 1 1 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein MMS1_N PF10433.9 CBZ29447.1 - 0.061 11.9 0.0 0.88 8.1 0.0 2.1 2 0 0 2 2 2 0 Mono-functional DNA-alkylating methyl methanesulfonate N-term ANAPC4_WD40 PF12894.7 CBZ29447.1 - 0.14 12.4 0.1 24 5.3 0.0 3.4 2 1 2 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain AMMECR1 PF01871.17 CBZ29449.1 - 2.2e-46 157.5 0.0 2.6e-46 157.3 0.0 1.0 1 0 0 1 1 1 1 AMMECR1 DSPc PF00782.20 CBZ29450.1 - 2.9e-12 46.5 0.0 5.3e-12 45.7 0.0 1.5 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 CBZ29450.1 - 9.7e-11 41.7 0.0 2.1e-10 40.6 0.0 1.5 1 0 0 1 1 1 1 Protein-tyrosine phosphatase CDKN3 PF05706.12 CBZ29450.1 - 5.3e-05 22.9 0.0 9.5e-05 22.1 0.0 1.4 1 0 0 1 1 1 1 Cyclin-dependent kinase inhibitor 3 (CDKN3) PTPlike_phytase PF14566.6 CBZ29450.1 - 9.3e-05 22.6 0.0 0.0002 21.5 0.0 1.6 1 0 0 1 1 1 1 Inositol hexakisphosphate Y_phosphatase3 PF13350.6 CBZ29450.1 - 0.012 15.5 0.0 0.023 14.7 0.0 1.4 1 0 0 1 1 1 0 Tyrosine phosphatase family AKAP7_NLS PF10469.9 CBZ29451.1 - 5.4e-42 144.0 0.0 6.6e-42 143.8 0.0 1.1 1 0 0 1 1 1 1 AKAP7 2'5' RNA ligase-like domain 2_5_RNA_ligase2 PF13563.6 CBZ29451.1 - 1.8e-07 31.2 0.0 2.7e-07 30.6 0.0 1.3 1 0 0 1 1 1 1 2'-5' RNA ligase superfamily EF-hand_7 PF13499.6 CBZ29452.1 - 2.9e-11 43.6 0.6 0.00067 20.1 0.0 2.9 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_6 PF13405.6 CBZ29452.1 - 1.8e-10 39.9 0.9 0.002 17.9 0.1 3.8 4 0 0 4 4 4 2 EF-hand domain EF-hand_1 PF00036.32 CBZ29452.1 - 1.1e-08 34.0 1.8 0.0022 17.4 0.1 4.0 5 0 0 5 5 5 2 EF hand EF-hand_8 PF13833.6 CBZ29452.1 - 3.2e-07 30.1 6.5 0.0089 15.9 0.5 4.5 2 1 3 5 5 5 3 EF-hand domain pair EFhand_Ca_insen PF08726.10 CBZ29452.1 - 0.0016 18.5 0.1 0.26 11.4 0.0 2.5 2 0 0 2 2 2 1 Ca2+ insensitive EF hand EF-hand_5 PF13202.6 CBZ29452.1 - 0.024 14.1 0.4 11 5.7 0.1 3.1 3 0 0 3 3 3 0 EF hand DUF881 PF05949.12 CBZ29452.1 - 0.16 11.8 0.0 0.26 11.1 0.0 1.4 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF881) Kinesin PF00225.23 CBZ29454.1 - 1.2e-100 336.7 0.3 1.2e-100 336.7 0.3 2.9 3 0 0 3 3 3 1 Kinesin motor domain Microtub_bd PF16796.5 CBZ29454.1 - 1.2e-26 93.4 2.4 5.9e-26 91.2 0.0 3.2 3 0 0 3 3 3 1 Microtubule binding DUF3800 PF12686.7 CBZ29454.1 - 0.07 13.8 0.2 30 5.3 0.2 4.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3800) zf-C2H2_9 PF16293.5 CBZ29454.1 - 0.26 11.2 6.7 0.054 13.4 1.3 2.8 2 0 0 2 2 2 0 C2H2 type zinc-finger (1 copy) AAA_16 PF13191.6 CBZ29454.1 - 3.5 8.0 0.0 3.5 8.0 0.0 4.3 4 2 0 4 4 4 0 AAA ATPase domain S4 PF01479.25 CBZ29455.1 - 6.6e-05 22.5 0.0 0.00012 21.7 0.0 1.5 1 0 0 1 1 1 1 S4 domain UQ_con PF00179.26 CBZ29456.1 - 2.9e-35 120.9 0.0 4.6e-35 120.3 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme DUF934 PF06073.12 CBZ29456.1 - 0.21 11.5 0.0 0.36 10.7 0.0 1.3 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF934) Mut7-C PF01927.16 CBZ29457.1 - 2.6e-46 157.3 0.6 4.2e-46 156.7 0.6 1.3 1 0 0 1 1 1 1 Mut7-C RNAse domain E6 PF00518.17 CBZ29457.1 - 0.13 12.7 1.7 0.81 10.2 1.9 2.2 1 1 1 2 2 2 0 Early Protein (E6) LSM PF01423.22 CBZ29458.1 - 8.4e-12 44.6 0.1 1.1e-11 44.2 0.1 1.2 1 0 0 1 1 1 1 LSM domain Chromosome_seg PF13889.6 CBZ29458.1 - 0.034 14.3 0.1 0.061 13.5 0.1 1.4 1 0 0 1 1 1 0 Chromosome segregation during meiosis SM-ATX PF14438.6 CBZ29458.1 - 0.13 12.4 0.0 0.25 11.5 0.0 1.4 1 0 0 1 1 1 0 Ataxin 2 SM domain Pan3_PK PF18101.1 CBZ29459.1 - 1e-39 135.6 0.6 1.5e-39 135.2 0.6 1.2 1 0 0 1 1 1 1 Pan3 Pseudokinase domain LRR_4 PF12799.7 CBZ29460.1 - 7.2e-13 48.5 3.5 0.0006 20.1 0.2 4.2 4 0 0 4 4 4 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CBZ29460.1 - 6.6e-12 45.0 6.6 1.1e-08 34.7 2.2 4.2 4 1 0 4 4 4 2 Leucine rich repeat LRR_9 PF14580.6 CBZ29460.1 - 0.004 16.7 0.1 1.7 8.1 0.0 2.8 3 0 0 3 3 3 2 Leucine-rich repeat LRR_6 PF13516.6 CBZ29460.1 - 0.018 15.1 2.1 4.9 7.5 0.0 3.7 3 0 0 3 3 3 0 Leucine Rich repeat LRR_1 PF00560.33 CBZ29460.1 - 0.075 13.6 1.2 17 6.4 0.0 4.3 5 0 0 5 5 5 0 Leucine Rich Repeat 4PPT_N PF17837.1 CBZ29461.1 - 0.0015 18.6 1.1 0.0045 17.1 1.1 1.9 1 1 0 1 1 1 1 4'-phosphopantetheinyl transferase N-terminal domain T6SS_VasE PF05936.12 CBZ29461.1 - 0.23 10.1 0.0 0.34 9.6 0.0 1.2 1 0 0 1 1 1 0 Bacterial Type VI secretion, VC_A0110, EvfL, ImpJ, VasE RRM_1 PF00076.22 CBZ29462.1 - 2.8e-10 39.8 0.8 6.7e-05 22.6 0.2 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF2967 PF11179.8 CBZ29462.1 - 0.0084 14.3 3.3 0.011 13.9 3.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2967) RRM_5 PF13893.6 CBZ29462.1 - 0.037 13.6 0.1 0.17 11.5 0.0 2.0 1 1 1 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Cyclin_N PF00134.23 CBZ29463.1 - 7.6e-08 32.2 0.4 1.6e-07 31.1 0.4 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain RIC1 PF07064.13 CBZ29464.1 - 2.7e-42 144.9 0.0 4.9e-42 144.1 0.0 1.4 1 0 0 1 1 1 1 RIC1 ANAPC4_WD40 PF12894.7 CBZ29464.1 - 0.00063 20.0 0.0 0.086 13.1 0.0 3.7 4 0 0 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain IKI3 PF04762.12 CBZ29464.1 - 0.19 9.7 0.2 2.8 5.8 0.0 2.5 3 0 0 3 3 3 0 IKI3 family DUF1561 PF07598.11 CBZ29464.1 - 0.26 9.4 0.0 0.39 8.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1561) Pkinase PF00069.25 CBZ29465.1 - 1.1e-48 165.9 0.0 1.8e-48 165.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ29465.1 - 4e-31 108.2 0.0 9.6e-31 107.0 0.0 1.7 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 CBZ29465.1 - 0.004 17.1 0.0 0.0087 16.0 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family RXLR_WY PF18634.1 CBZ29465.1 - 0.035 14.0 0.6 0.068 13.1 0.6 1.4 1 0 0 1 1 1 0 RXLR phytopathogen effector protein WY-domain Seadorna_VP7 PF07387.11 CBZ29465.1 - 0.076 12.1 0.1 0.12 11.4 0.1 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Pkinase_fungal PF17667.1 CBZ29465.1 - 0.1 11.4 0.0 0.19 10.5 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase Kdo PF06293.14 CBZ29465.1 - 0.15 11.4 0.0 0.31 10.4 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 CBZ29465.1 - 0.17 11.5 0.0 0.31 10.6 0.0 1.4 1 0 0 1 1 1 0 RIO1 family Mub_B2 PF17966.1 CBZ29467.1 - 0.083 13.6 0.0 0.18 12.5 0.0 1.5 1 0 0 1 1 1 0 Mub B2-like domain Pkinase PF00069.25 CBZ29468.1 - 1.9e-49 168.4 0.0 3e-49 167.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ29468.1 - 1.9e-35 122.4 0.0 3.6e-35 121.5 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase DUF1356 PF07092.12 CBZ29468.1 - 0.059 12.6 0.1 7.8 5.7 0.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1356) HemY_N PF07219.13 CBZ29468.1 - 0.16 12.2 1.1 1.9 8.7 1.3 2.3 2 0 0 2 2 2 0 HemY protein N-terminus Cyclin PF08613.11 CBZ29469.1 - 7.6e-24 84.9 0.3 1e-23 84.4 0.3 1.1 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 CBZ29469.1 - 4.6e-10 39.3 0.3 5.8e-10 39.0 0.3 1.2 1 0 0 1 1 1 1 Cyclin, N-terminal domain IFP_35_N PF07334.13 CBZ29470.1 - 0.14 12.2 0.0 0.46 10.6 0.0 1.8 1 0 0 1 1 1 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus RRM_8 PF11835.8 CBZ29471.1 - 5.1e-08 33.0 0.0 1.1e-07 31.9 0.0 1.5 1 0 0 1 1 1 1 RRM-like domain RRM_1 PF00076.22 CBZ29471.1 - 0.0031 17.3 0.0 0.061 13.2 0.0 2.2 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.22 CBZ29472.1 - 4.8e-13 48.7 0.0 2e-05 24.3 0.0 3.7 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 CBZ29472.1 - 3.8e-05 23.5 0.2 0.00013 21.7 0.0 2.0 3 0 0 3 3 3 1 Occluded RNA-recognition motif RRM_8 PF11835.8 CBZ29472.1 - 0.0065 16.7 0.0 0.021 15.0 0.0 1.8 1 1 0 1 1 1 1 RRM-like domain RRM_5 PF13893.6 CBZ29472.1 - 0.14 11.8 0.0 15 5.2 0.0 2.7 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF4523 PF15023.6 CBZ29472.1 - 0.14 11.9 0.0 2.3 8.0 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF4523) Tmemb_55A PF09788.9 CBZ29473.1 - 0.0044 16.1 0.7 0.014 14.5 0.7 1.8 1 0 0 1 1 1 1 Transmembrane protein 55A tRNA-synt_2d PF01409.20 CBZ29474.1 - 2e-79 266.5 0.3 2.7e-79 266.1 0.3 1.2 1 0 0 1 1 1 1 tRNA synthetases class II core domain (F) PheRS_DBD1 PF18552.1 CBZ29474.1 - 2.4e-09 36.8 0.2 6.2e-09 35.5 0.2 1.7 1 0 0 1 1 1 1 PheRS DNA binding domain 1 PheRS_DBD3 PF18553.1 CBZ29474.1 - 5.9e-08 32.9 0.0 1.4e-06 28.4 0.0 3.0 3 0 0 3 3 3 1 PheRS DNA binding domain 3 PheRS_DBD2 PF18554.1 CBZ29474.1 - 0.00026 20.9 0.6 0.00055 19.9 0.6 1.6 1 0 0 1 1 1 1 PheRS DNA binding domain 2 tRNA-synt_2 PF00152.20 CBZ29474.1 - 0.00092 18.4 0.5 0.0027 16.8 0.3 1.9 2 0 0 2 2 2 1 tRNA synthetases class II (D, K and N) tRNA_synthFbeta PF17759.1 CBZ29474.1 - 0.0021 17.5 0.0 1.2 8.5 0.0 2.4 2 0 0 2 2 2 2 Phenylalanyl tRNA synthetase beta chain CLM domain tRNA-synt_2b PF00587.25 CBZ29474.1 - 0.005 16.8 0.0 0.012 15.5 0.0 1.6 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HTH_24 PF13412.6 CBZ29474.1 - 0.051 13.1 0.7 0.23 11.1 0.0 2.4 3 0 0 3 3 3 0 Winged helix-turn-helix DNA-binding HTH_AsnC-type PF13404.6 CBZ29474.1 - 0.27 11.1 0.8 1.5 8.7 0.0 2.5 3 0 0 3 3 3 0 AsnC-type helix-turn-helix domain Ribosomal_L18A PF01775.17 CBZ29475.1 - 5.8e-41 139.4 1.4 7.6e-41 139.0 1.4 1.2 1 0 0 1 1 1 1 Ribosomal proteins 50S-L18Ae/60S-L20/60S-L18A CTP_transf_like PF01467.26 CBZ29476.1 - 3.6e-44 150.4 0.0 2.1e-25 89.6 0.0 2.2 2 0 0 2 2 2 2 Cytidylyltransferase-like FAD_syn PF06574.12 CBZ29476.1 - 0.00028 20.8 0.6 1 9.2 0.0 3.3 2 1 0 2 2 2 2 FAD synthetase Abhydrolase_6 PF12697.7 CBZ29478.1 - 2.5e-16 61.0 0.0 2.8e-16 60.8 0.0 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 CBZ29478.1 - 1.9e-10 40.5 0.1 2.6e-10 40.0 0.1 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 CBZ29478.1 - 0.00057 19.6 0.0 0.0009 19.0 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Ser_hydrolase PF06821.13 CBZ29478.1 - 0.00062 19.7 0.0 0.0013 18.6 0.0 1.5 1 0 0 1 1 1 1 Serine hydrolase PGAP1 PF07819.13 CBZ29478.1 - 0.0013 18.5 0.0 0.0018 18.0 0.0 1.2 1 0 0 1 1 1 1 PGAP1-like protein Chlorophyllase2 PF12740.7 CBZ29478.1 - 0.0046 15.9 0.0 0.013 14.4 0.0 1.7 2 0 0 2 2 2 1 Chlorophyllase enzyme Lipase_3 PF01764.25 CBZ29478.1 - 0.014 15.3 0.0 0.027 14.3 0.0 1.5 1 0 0 1 1 1 0 Lipase (class 3) Peptidase_S9 PF00326.21 CBZ29478.1 - 0.016 14.7 0.0 0.036 13.5 0.0 1.5 1 0 0 1 1 1 0 Prolyl oligopeptidase family Abhydrolase_9 PF10081.9 CBZ29478.1 - 0.021 13.9 0.0 0.028 13.5 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta-hydrolase family Lipase PF00151.19 CBZ29478.1 - 0.035 13.4 0.0 0.057 12.7 0.0 1.3 1 0 0 1 1 1 0 Lipase Abhydrolase_5 PF12695.7 CBZ29478.1 - 0.056 13.2 0.0 0.091 12.5 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family PAF-AH_p_II PF03403.13 CBZ29478.1 - 0.071 11.6 0.0 0.16 10.5 0.0 1.5 1 0 0 1 1 1 0 Platelet-activating factor acetylhydrolase, isoform II Abhydrolase_3 PF07859.13 CBZ29478.1 - 0.093 12.6 1.1 0.23 11.3 0.0 2.2 3 1 1 4 4 4 0 alpha/beta hydrolase fold V_ATPase_I PF01496.19 CBZ29479.1 - 5.2e-245 815.2 0.2 6.2e-245 815.0 0.2 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family GMC_oxred_N PF00732.19 CBZ29480.1 - 4.8e-07 29.4 0.0 0.00035 20.0 0.0 2.6 2 1 0 2 2 2 2 GMC oxidoreductase DAO PF01266.24 CBZ29480.1 - 8.5e-07 28.9 0.7 1.8e-05 24.5 0.2 2.5 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 CBZ29480.1 - 1.9e-05 23.9 0.9 0.0012 18.0 0.2 2.3 2 0 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.6 CBZ29480.1 - 0.00029 21.0 0.2 0.0008 19.6 0.2 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 CBZ29480.1 - 0.0018 17.5 0.1 0.0033 16.7 0.1 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 CBZ29480.1 - 0.0022 17.1 0.1 0.0033 16.5 0.1 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Trp_halogenase PF04820.14 CBZ29480.1 - 0.0045 15.9 0.0 0.0074 15.2 0.0 1.3 1 0 0 1 1 1 1 Tryptophan halogenase HI0933_like PF03486.14 CBZ29480.1 - 0.0081 14.9 0.2 0.011 14.4 0.2 1.2 1 0 0 1 1 1 1 HI0933-like protein NAD_binding_9 PF13454.6 CBZ29480.1 - 0.013 15.5 0.1 0.025 14.6 0.1 1.4 1 0 0 1 1 1 0 FAD-NAD(P)-binding GIDA PF01134.22 CBZ29480.1 - 0.096 11.8 0.1 0.14 11.2 0.1 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A AlaDh_PNT_C PF01262.21 CBZ29480.1 - 0.11 11.7 0.7 0.64 9.3 0.0 2.1 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain Thi4 PF01946.17 CBZ29480.1 - 0.16 11.2 0.0 0.39 9.9 0.0 1.5 1 0 0 1 1 1 0 Thi4 family Pyr_redox_3 PF13738.6 CBZ29480.1 - 0.19 10.9 0.3 0.37 10.0 0.3 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase CLASP_N PF12348.8 CBZ29481.1 - 7.7e-11 42.0 2.2 2.4e-09 37.1 1.9 2.5 2 0 0 2 2 2 1 CLASP N terminal DUF3022 PF11226.8 CBZ29481.1 - 0.0026 18.2 0.9 0.013 15.9 0.9 2.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3022) Cnd1 PF12717.7 CBZ29481.1 - 0.0099 15.9 0.5 8.5 6.4 0.0 3.2 3 0 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 CBZ29481.1 - 0.033 14.4 25.3 5.7 7.5 0.1 8.0 8 0 0 8 8 8 0 HEAT repeat SNase PF00565.17 CBZ29482.1 - 4.2e-55 184.8 1.9 9.9e-16 58.2 0.0 5.4 5 0 0 5 5 5 5 Staphylococcal nuclease homologue TUDOR PF00567.24 CBZ29482.1 - 9.4e-17 61.2 0.0 2.2e-16 60.0 0.0 1.6 1 0 0 1 1 1 1 Tudor domain Agenet PF05641.12 CBZ29482.1 - 0.004 17.6 0.1 0.027 14.9 0.1 2.5 2 0 0 2 2 2 1 Agenet domain DUF4537 PF15057.6 CBZ29482.1 - 0.029 14.4 0.0 0.19 11.7 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4537) RIF5_SNase_1 PF18187.1 CBZ29482.1 - 0.086 12.6 0.0 2.6 7.8 0.0 2.4 2 0 0 2 2 2 0 TbRIF5 SNase domain 1 SBBP PF06739.11 CBZ29482.1 - 0.51 10.4 3.5 0.63 10.1 0.7 2.3 2 0 0 2 2 2 0 Beta-propeller repeat UQ_con PF00179.26 CBZ29483.1 - 1.9e-40 137.8 0.0 2.5e-40 137.3 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Peptidase_C2 PF00648.21 CBZ29484.1 - 1e-06 28.0 0.0 3.7e-06 26.2 0.0 1.8 2 0 0 2 2 2 1 Calpain family cysteine protease RRM_1 PF00076.22 CBZ29485.1 - 0.0057 16.5 0.0 0.012 15.5 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-B_box PF00643.24 CBZ29485.1 - 0.091 12.9 2.7 0.24 11.6 2.7 1.7 1 0 0 1 1 1 0 B-box zinc finger Vps23_core PF09454.10 CBZ29486.1 - 9.6e-18 63.9 0.0 2.2e-17 62.7 0.0 1.7 1 0 0 1 1 1 1 Vps23 core domain CUE PF02845.16 CBZ29486.1 - 0.22 11.3 0.6 0.63 9.8 0.0 2.0 1 1 1 2 2 2 0 CUE domain WD40 PF00400.32 CBZ29487.1 - 1.1e-07 32.4 4.1 2.6e-05 24.9 0.3 4.5 3 0 0 3 3 3 1 WD domain, G-beta repeat Cpn60_TCP1 PF00118.24 CBZ29488.1 - 3.2e-153 510.9 0.8 3.6e-153 510.7 0.8 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family BESS PF02944.20 CBZ29488.1 - 0.13 12.1 0.0 0.97 9.3 0.0 2.1 2 0 0 2 2 2 0 BESS motif Y_phosphatase2 PF03162.13 CBZ29489.1 - 1.9e-22 79.6 0.0 1.8e-21 76.4 0.0 2.2 1 1 0 1 1 1 1 Tyrosine phosphatase family IFT57 PF10498.9 CBZ29489.1 - 1.7 7.5 7.2 7 5.5 7.2 1.8 1 1 0 1 1 1 0 Intra-flagellar transport protein 57 Pkinase PF00069.25 CBZ29490.1 - 8.2e-32 110.6 0.1 1.8e-26 93.1 0.0 2.4 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ29490.1 - 3.4e-16 59.3 0.1 7.8e-16 58.1 0.1 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CBZ29490.1 - 0.0042 15.9 0.0 0.0095 14.7 0.0 1.5 1 0 0 1 1 1 1 Fungal protein kinase FTA2 PF13095.6 CBZ29490.1 - 0.0057 16.3 0.0 0.017 14.8 0.0 1.8 1 0 0 1 1 1 1 Kinetochore Sim4 complex subunit FTA2 DUF747 PF05346.11 CBZ29490.1 - 0.029 13.8 0.2 0.046 13.2 0.2 1.2 1 0 0 1 1 1 0 Eukaryotic membrane protein family APH PF01636.23 CBZ29490.1 - 0.19 11.6 0.0 0.38 10.6 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Maf PF02545.14 CBZ29491.1 - 4.6e-16 59.1 0.0 5.2e-16 58.9 0.0 1.0 1 0 0 1 1 1 1 Maf-like protein Mre11_DNA_bind PF04152.14 CBZ29491.1 - 0.078 13.3 0.0 0.16 12.3 0.0 1.4 1 0 0 1 1 1 0 Mre11 DNA-binding presumed domain DUF445 PF04286.12 CBZ29492.1 - 0.014 15.2 1.9 0.014 15.2 1.9 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF445) Syntaxin_2 PF14523.6 CBZ29492.1 - 3.4 8.1 12.7 11 6.4 0.5 3.8 3 0 0 3 3 3 0 Syntaxin-like protein Metallophos_2 PF12850.7 CBZ29493.1 - 2.9e-14 53.6 0.0 3.6e-14 53.3 0.0 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain WD40 PF00400.32 CBZ29494.1 - 1.2e-07 32.2 11.7 0.087 13.7 0.2 5.2 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBZ29494.1 - 0.0016 18.7 0.1 0.11 12.8 0.0 3.2 3 0 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain LSM PF01423.22 CBZ29495.1 - 6e-14 51.5 0.1 7e-14 51.3 0.1 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 CBZ29495.1 - 0.01 16.0 0.1 0.012 15.8 0.1 1.2 1 0 0 1 1 1 0 Ataxin 2 SM domain HECT PF00632.25 CBZ29497.1 - 2.3e-69 234.2 0.0 3.4e-69 233.7 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) ZZ PF00569.17 CBZ29497.1 - 8.4e-05 22.3 9.4 0.00021 21.0 9.4 1.7 1 0 0 1 1 1 1 Zinc finger, ZZ type HEAT PF02985.22 CBZ29497.1 - 0.14 12.5 0.1 53 4.5 0.0 3.9 3 0 0 3 3 3 0 HEAT repeat UNC45-central PF11701.8 CBZ29497.1 - 0.33 10.9 4.4 8.7 6.3 0.3 3.5 4 0 0 4 4 4 0 Myosin-binding striated muscle assembly central CRM1_C PF08767.11 CBZ29498.1 - 1.2e-59 202.1 0.7 1.2e-59 202.1 0.7 2.9 4 0 0 4 4 4 1 CRM1 C terminal Xpo1 PF08389.12 CBZ29498.1 - 5.3e-27 94.7 4.9 1.4e-26 93.3 1.0 3.7 4 0 0 4 4 4 1 Exportin 1-like protein CRM1_repeat_2 PF18784.1 CBZ29498.1 - 1e-26 92.4 1.8 3.3e-26 90.7 1.8 1.9 1 0 0 1 1 1 1 CRM1 / Exportin repeat 2 CRM1_repeat_3 PF18787.1 CBZ29498.1 - 6.6e-24 83.8 1.4 2.5e-23 81.9 1.4 2.1 1 0 0 1 1 1 1 CRM1 / Exportin repeat 3 IBN_N PF03810.19 CBZ29498.1 - 8.6e-10 38.4 0.2 7.6e-09 35.4 0.1 2.8 3 0 0 3 3 3 1 Importin-beta N-terminal domain CRM1_repeat PF18777.1 CBZ29498.1 - 1.6e-09 37.1 1.1 5.3e-09 35.5 1.1 2.0 1 0 0 1 1 1 1 Chromosome region maintenance or exportin repeat DUF4473 PF14747.6 CBZ29498.1 - 0.0023 18.5 1.4 4.8 7.8 0.1 3.8 3 1 1 4 4 4 1 Domain of unknown function (DUF4473) Peptidase_C27 PF05407.12 CBZ29498.1 - 0.067 13.3 1.6 0.32 11.1 1.0 2.4 3 0 0 3 3 3 0 Rubella virus endopeptidase Mito_carr PF00153.27 CBZ29499.1 - 4.3e-46 154.8 1.4 6.4e-15 54.9 0.0 3.0 2 1 1 3 3 3 3 Mitochondrial carrier protein LRR_3 PF07725.12 CBZ29499.1 - 0.19 11.7 0.9 23 5.0 0.0 3.0 3 0 0 3 3 3 0 Leucine Rich Repeat ThrE_2 PF12821.7 CBZ29499.1 - 0.29 11.3 3.3 0.24 11.5 1.5 1.8 2 0 0 2 2 2 0 Threonine/Serine exporter, ThrE Mito_carr PF00153.27 CBZ29500.1 - 1.5e-51 172.3 1.6 7.4e-18 64.3 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF1455 PF07306.11 CBZ29501.1 - 0.0071 16.3 0.9 0.049 13.6 0.0 3.0 2 0 0 2 2 2 1 Protein of unknown function (DUF1455) PPR_2 PF13041.6 CBZ29502.1 - 0.0005 20.2 0.3 17 5.7 0.0 4.5 4 1 1 5 5 5 3 PPR repeat family ELO PF01151.18 CBZ29504.1 - 3.9e-49 167.4 18.4 5.2e-49 167.0 18.4 1.1 1 0 0 1 1 1 1 GNS1/SUR4 family Ank PF00023.30 CBZ29506.1 - 1.2e-06 28.7 2.3 0.015 15.8 0.4 2.8 2 0 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.6 CBZ29506.1 - 4e-06 27.3 0.3 2.2e-05 24.9 0.2 2.4 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 CBZ29506.1 - 8.5e-06 26.3 0.0 1.9e-05 25.1 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 CBZ29506.1 - 1.1e-05 25.6 0.9 2.8e-05 24.3 0.9 1.8 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 CBZ29506.1 - 1.9e-05 24.7 0.3 0.044 14.3 0.0 3.0 2 0 0 2 2 2 2 Ankyrin repeat CSN8_PSD8_EIF3K PF10075.9 CBZ29508.1 - 3e-25 88.9 0.0 4.7e-25 88.3 0.0 1.2 1 0 0 1 1 1 1 CSN8/PSMD8/EIF3K family PPR_2 PF13041.6 CBZ29509.1 - 2.6e-39 133.2 21.3 4.6e-12 45.9 0.0 12.2 9 3 4 13 13 13 8 PPR repeat family PPR_3 PF13812.6 CBZ29509.1 - 6.5e-31 106.2 19.6 1.4e-11 44.3 0.1 9.9 6 3 3 10 10 10 8 Pentatricopeptide repeat domain PPR_long PF17177.4 CBZ29509.1 - 1e-13 51.2 14.3 2e-09 37.1 0.6 6.3 4 2 2 6 6 6 3 Pentacotripeptide-repeat region of PRORP PPR PF01535.20 CBZ29509.1 - 1e-13 50.5 14.4 0.00014 21.8 0.0 9.8 11 0 0 11 11 11 4 PPR repeat PPR_1 PF12854.7 CBZ29509.1 - 8.6e-10 38.1 18.1 5.4e-07 29.2 0.0 8.2 9 0 0 9 9 9 1 PPR repeat COX5A PF02284.16 CBZ29509.1 - 0.0023 17.9 0.9 0.45 10.6 0.1 3.0 2 1 1 3 3 3 1 Cytochrome c oxidase subunit Va RPM2 PF08579.11 CBZ29509.1 - 0.014 15.8 6.1 6 7.3 1.1 5.0 4 1 1 5 5 5 0 Mitochondrial ribonuclease P subunit (RPM2) ECSIT PF06239.11 CBZ29509.1 - 0.015 14.4 1.7 4.5 6.3 0.1 3.9 3 1 1 4 4 4 0 Evolutionarily conserved signalling intermediate in Toll pathway RCDG1 PF15725.5 CBZ29510.1 - 0.24 11.8 4.2 0.67 10.4 4.2 1.7 1 0 0 1 1 1 0 Renal cancer differentiation gene 1 protein Pox_A_type_inc PF04508.12 CBZ29510.1 - 0.8 9.7 5.0 0.56 10.1 2.5 2.1 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat Flagellin_N PF00669.20 CBZ29510.1 - 3.3 7.8 10.5 0.33 11.1 0.4 3.1 4 0 0 4 4 4 0 Bacterial flagellin N-terminal helical region DUF4140 PF13600.6 CBZ29510.1 - 4.9 7.7 7.1 9.3 6.8 0.0 4.3 5 1 1 6 6 6 0 N-terminal domain of unknown function (DUF4140) ArfGap PF01412.18 CBZ29511.1 - 3.6e-27 94.7 0.0 7e-27 93.8 0.0 1.4 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf Apolipoprotein PF01442.18 CBZ29511.1 - 0.035 14.0 1.0 0.052 13.4 1.0 1.2 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain TF_Zn_Ribbon PF08271.12 CBZ29511.1 - 0.24 10.9 2.5 0.43 10.1 2.5 1.3 1 0 0 1 1 1 0 TFIIB zinc-binding PHTB1_C PF14728.6 CBZ29512.1 - 7e-104 347.9 0.0 1e-103 347.4 0.0 1.2 1 0 0 1 1 1 1 PTHB1 C-terminus PHTB1_N PF14727.6 CBZ29512.1 - 3.8e-91 306.5 0.0 2.4e-90 303.9 0.0 1.9 1 1 0 1 1 1 1 PTHB1 N-terminus BBS2_Mid PF14783.6 CBZ29512.1 - 0.18 11.9 0.0 0.43 10.6 0.0 1.6 1 0 0 1 1 1 0 Ciliary BBSome complex subunit 2, middle region DUF4072 PF13284.6 CBZ29512.1 - 5.3 7.6 8.7 24 5.5 0.0 3.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4072) UCH PF00443.29 CBZ29513.1 - 4.1e-31 108.4 0.0 6.2e-31 107.8 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 CBZ29513.1 - 2.4e-12 47.1 0.1 3.7e-06 26.8 0.0 2.3 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase SFTA2 PF15210.6 CBZ29513.1 - 0.11 12.4 0.2 2.2 8.3 0.0 2.4 2 0 0 2 2 2 0 Surfactant-associated protein 2 CRAL_TRIO PF00650.20 CBZ29514.1 - 5e-39 133.6 0.0 7.2e-39 133.1 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain GOLD_2 PF13897.6 CBZ29514.1 - 0.0002 21.9 0.1 0.3 11.6 0.0 2.3 1 1 1 2 2 2 2 Golgi-dynamics membrane-trafficking EMP24_GP25L PF01105.24 CBZ29514.1 - 0.093 12.7 0.0 0.14 12.1 0.0 1.2 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD CRAL_TRIO PF00650.20 CBZ29515.1 - 4.6e-31 107.7 0.0 1e-30 106.5 0.0 1.6 1 1 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.6 CBZ29515.1 - 0.00079 19.6 0.0 0.0017 18.5 0.0 1.5 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain DUF2066 PF09839.9 CBZ29515.1 - 0.055 12.9 0.1 0.083 12.3 0.1 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2066) SHS2_Rpb7-N PF03876.17 CBZ29516.1 - 1e-14 54.6 0.0 1.6e-14 54.0 0.0 1.3 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 Pkinase PF00069.25 CBZ29517.1 - 2.8e-08 33.4 0.0 4.4e-08 32.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ29517.1 - 8.9e-06 25.2 0.0 1.4e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 CBZ29517.1 - 0.00041 20.4 0.1 0.00041 20.4 0.1 1.7 2 1 0 2 2 2 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 CBZ29517.1 - 0.0054 15.7 0.0 0.0085 15.1 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Choline_kinase PF01633.20 CBZ29517.1 - 0.0079 15.8 0.0 0.013 15.1 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase Pep_deformylase PF01327.21 CBZ29518.1 - 3.6e-27 94.9 0.0 4.5e-27 94.6 0.0 1.1 1 0 0 1 1 1 1 Polypeptide deformylase DUF1158 PF06643.11 CBZ29518.1 - 0.17 12.4 0.0 0.31 11.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1158) WLM PF08325.10 CBZ29519.1 - 1.4e-34 119.8 0.0 1.2e-33 116.8 0.0 2.0 1 1 0 1 1 1 1 WLM domain DUF45 PF01863.17 CBZ29519.1 - 0.0069 16.4 1.1 0.013 15.6 1.1 1.3 1 0 0 1 1 1 1 Protein of unknown function DUF45 Peptidase_C97 PF05903.14 CBZ29521.1 - 1.2e-16 60.8 0.1 2.4e-16 59.9 0.1 1.5 1 0 0 1 1 1 1 PPPDE putative peptidase domain PUL PF08324.11 CBZ29521.1 - 0.0029 16.9 1.0 0.0049 16.1 1.0 1.3 1 0 0 1 1 1 1 PUL domain CPSF_A PF03178.15 CBZ29522.1 - 1.1e-64 218.8 0.0 1.8e-64 218.1 0.0 1.3 1 0 0 1 1 1 1 CPSF A subunit region MMS1_N PF10433.9 CBZ29522.1 - 3.7e-19 68.7 0.0 3.2e-13 49.2 0.0 3.6 3 1 0 3 3 3 2 Mono-functional DNA-alkylating methyl methanesulfonate N-term LicD PF04991.13 CBZ29523.1 - 1.7e-07 31.6 0.0 2.8e-07 30.9 0.0 1.2 1 0 0 1 1 1 1 LicD family mRNA_cap_enzyme PF01331.19 CBZ29524.1 - 1.7e-09 37.8 0.0 2.8e-09 37.1 0.0 1.3 1 0 0 1 1 1 1 mRNA capping enzyme, catalytic domain ADK PF00406.22 CBZ29524.1 - 1.1e-06 28.9 0.0 2.3e-06 27.8 0.0 1.6 1 1 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 CBZ29524.1 - 2.1e-06 28.2 0.0 1e-05 26.0 0.0 2.0 1 1 0 1 1 1 1 AAA domain mRNA_cap_C PF03919.15 CBZ29524.1 - 1.3e-05 25.8 0.0 3.8e-05 24.3 0.0 1.7 2 0 0 2 2 1 1 mRNA capping enzyme, C-terminal domain AAA_18 PF13238.6 CBZ29524.1 - 7.4e-05 23.3 0.0 0.00019 22.0 0.0 1.7 1 1 0 1 1 1 1 AAA domain Thymidylate_kin PF02223.17 CBZ29524.1 - 0.0052 16.5 0.0 1.3 8.7 0.0 2.3 1 1 1 2 2 2 2 Thymidylate kinase AAA_33 PF13671.6 CBZ29524.1 - 0.0075 16.4 0.0 0.021 15.0 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.6 CBZ29524.1 - 0.016 15.5 0.0 0.032 14.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 CBZ29524.1 - 0.045 13.5 0.0 0.079 12.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.6 CBZ29524.1 - 0.055 13.5 0.0 0.095 12.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 CBZ29524.1 - 0.089 13.2 0.0 0.57 10.5 0.0 2.1 1 1 0 1 1 1 0 AAA ATPase domain AAA_28 PF13521.6 CBZ29524.1 - 0.095 12.9 0.0 0.23 11.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain SRP54 PF00448.22 CBZ29524.1 - 0.1 12.3 0.0 0.16 11.6 0.0 1.2 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain Zeta_toxin PF06414.12 CBZ29524.1 - 0.21 10.8 0.0 0.67 9.2 0.0 1.8 2 0 0 2 2 2 0 Zeta toxin AAA_16 PF13191.6 CBZ29525.1 - 0.003 18.0 0.1 0.0062 16.9 0.1 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_18 PF13238.6 CBZ29525.1 - 0.0044 17.6 0.0 0.0089 16.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 CBZ29525.1 - 0.011 15.8 0.0 0.027 14.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.6 CBZ29525.1 - 0.028 14.8 0.1 0.063 13.7 0.1 1.7 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 CBZ29525.1 - 0.069 13.6 0.1 0.19 12.1 0.0 1.8 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) FliT PF05400.13 CBZ29525.1 - 0.11 13.3 2.7 1.7 9.5 0.0 2.7 2 0 0 2 2 2 0 Flagellar protein FliT PAM2 PF07145.15 CBZ29525.1 - 0.21 11.4 1.5 0.8 9.5 1.5 2.0 1 0 0 1 1 1 0 Ataxin-2 C-terminal region ING PF12998.7 CBZ29526.1 - 0.26 11.9 0.8 0.35 11.5 0.1 1.5 2 0 0 2 2 2 0 Inhibitor of growth proteins N-terminal histone-binding DEAD PF00270.29 CBZ29528.1 - 1.7e-21 76.8 0.2 1.3e-20 73.9 0.3 2.3 2 1 0 2 2 2 1 DEAD/DEAH box helicase Sec63 PF02889.16 CBZ29528.1 - 2.3e-17 63.0 0.0 9e-15 54.5 0.0 2.3 2 0 0 2 2 2 2 Sec63 Brl domain Helicase_C PF00271.31 CBZ29528.1 - 4.5e-07 30.2 0.0 2e-06 28.1 0.0 2.1 1 1 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 CBZ29528.1 - 1.8e-06 28.1 0.0 6.1e-06 26.3 0.0 1.8 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit T2SSE PF00437.20 CBZ29528.1 - 0.019 14.0 0.0 0.058 12.4 0.0 1.8 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_22 PF13401.6 CBZ29528.1 - 0.14 12.4 0.0 21 5.4 0.0 2.8 2 0 0 2 2 2 0 AAA domain UvrD-helicase PF00580.21 CBZ29528.1 - 0.17 11.4 0.0 0.4 10.2 0.0 1.6 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain Cyclase PF04199.13 CBZ29529.1 - 2.4e-08 34.3 0.1 1.8e-07 31.5 0.1 2.2 1 1 0 1 1 1 1 Putative cyclase Chloroa_b-bind PF00504.21 CBZ29532.1 - 0.021 15.3 1.4 0.025 15.1 0.5 1.4 1 1 0 1 1 1 0 Chlorophyll A-B binding protein PI3_PI4_kinase PF00454.27 CBZ29534.1 - 3.5e-45 154.8 0.2 5.9e-45 154.0 0.2 1.4 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FATC PF02260.20 CBZ29534.1 - 2e-10 40.3 0.7 2e-10 40.3 0.7 2.5 3 0 0 3 3 3 1 FATC domain FAT PF02259.23 CBZ29534.1 - 2.3e-08 33.7 1.6 2.6e-06 26.9 0.2 3.4 2 1 0 2 2 2 1 FAT domain DUF4395 PF14340.6 CBZ29534.1 - 0.051 13.9 0.5 0.18 12.2 0.5 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4395) MIP-T3 PF10243.9 CBZ29535.1 - 2.2e-26 92.0 0.0 4.4e-26 91.1 0.0 1.5 1 0 0 1 1 1 1 Microtubule-binding protein MIP-T3 CH-like domain Fib_alpha PF08702.10 CBZ29535.1 - 0.073 13.3 1.7 2.3 8.4 0.2 2.4 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family CCDC24 PF15669.5 CBZ29536.1 - 0.14 12.0 0.2 0.32 10.8 0.2 1.5 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 24 family rRNA_processing PF08524.11 CBZ29537.1 - 7.2e-10 39.1 37.4 1.3e-08 34.9 36.9 2.2 1 1 0 1 1 1 1 rRNA processing DUF4407 PF14362.6 CBZ29537.1 - 2 7.7 18.4 2.5 7.4 18.4 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Peptidase_M41 PF01434.18 CBZ29539.1 - 1.1e-46 159.1 0.2 1.7e-46 158.5 0.2 1.3 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.29 CBZ29539.1 - 5.2e-41 140.2 0.0 1e-40 139.2 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 CBZ29539.1 - 7.1e-05 23.2 0.1 0.00088 19.7 0.1 2.4 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 CBZ29539.1 - 0.0026 18.0 0.2 0.033 14.5 0.2 2.5 1 1 0 1 1 1 1 AAA domain TIP49 PF06068.13 CBZ29539.1 - 0.0091 15.2 0.1 0.019 14.2 0.0 1.5 1 1 0 1 1 1 1 TIP49 P-loop domain AAA_5 PF07728.14 CBZ29539.1 - 0.017 15.1 0.1 0.1 12.6 0.1 2.3 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 CBZ29539.1 - 0.024 14.4 0.0 0.064 13.0 0.0 1.8 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain Sigma54_activat PF00158.26 CBZ29539.1 - 0.04 13.6 0.0 0.18 11.5 0.0 2.1 1 1 0 1 1 1 0 Sigma-54 interaction domain Zeta_toxin PF06414.12 CBZ29539.1 - 0.04 13.2 0.1 0.093 12.0 0.1 1.5 1 0 0 1 1 1 0 Zeta toxin IstB_IS21 PF01695.17 CBZ29539.1 - 0.068 12.9 0.1 0.15 11.8 0.1 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein DUF2075 PF09848.9 CBZ29539.1 - 0.085 12.1 0.0 0.14 11.4 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) NACHT PF05729.12 CBZ29539.1 - 0.18 11.7 0.0 0.68 9.8 0.1 1.9 2 0 0 2 2 2 0 NACHT domain AAA_24 PF13479.6 CBZ29539.1 - 0.18 11.5 0.1 1.2 8.8 0.0 2.4 3 0 0 3 3 3 0 AAA domain AAA_2 PF07724.14 CBZ29539.1 - 0.23 11.5 0.6 2.4 8.2 0.4 2.5 1 1 0 1 1 1 0 AAA domain (Cdc48 subfamily) YqaJ PF09588.10 CBZ29541.1 - 4.5e-56 189.1 0.0 1.7e-55 187.2 0.0 1.9 1 1 0 1 1 1 1 YqaJ-like viral recombinase domain NUDIX PF00293.28 CBZ29544.1 - 9.3e-07 28.9 0.0 1.2e-06 28.6 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain PSP1 PF04468.12 CBZ29545.1 - 8.1e-23 80.5 1.5 1.3e-22 79.8 1.5 1.3 1 0 0 1 1 1 1 PSP1 C-terminal conserved region eIF3_p135 PF12807.7 CBZ29546.1 - 7.4e-12 45.7 0.0 1.3e-11 44.8 0.0 1.3 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit 135 CLU PF13236.6 CBZ29546.1 - 8.3e-07 29.1 0.0 1.8e-06 28.0 0.0 1.6 1 1 0 1 1 1 1 Clustered mitochondria zf-RING_4 PF14570.6 CBZ29546.1 - 0.13 12.1 4.5 0.39 10.5 4.5 1.9 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain ArfGap PF01412.18 CBZ29547.1 - 5.5e-42 142.5 0.2 9.2e-42 141.8 0.2 1.3 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf PMI_typeI PF01238.21 CBZ29548.1 - 1.3e-88 297.7 0.0 1.5e-88 297.5 0.0 1.0 1 0 0 1 1 1 1 Phosphomannose isomerase type I LcrG PF07216.12 CBZ29548.1 - 0.11 12.4 0.0 0.4 10.6 0.0 1.8 2 0 0 2 2 2 0 LcrG protein DinI PF06183.13 CBZ29548.1 - 0.12 12.7 0.0 29 5.1 0.0 2.5 2 0 0 2 2 2 0 DinI-like family AIPR PF10592.9 CBZ29548.1 - 0.22 11.1 0.0 0.28 10.8 0.0 1.2 1 0 0 1 1 1 0 AIPR protein PIF1 PF05970.14 CBZ29549.1 - 1.1e-35 123.5 0.1 2.9e-15 56.3 0.0 4.2 4 0 0 4 4 4 4 PIF1-like helicase AAA_30 PF13604.6 CBZ29549.1 - 7.9e-15 55.1 0.0 5.2e-13 49.1 0.0 3.0 2 1 0 2 2 2 1 AAA domain AAA_19 PF13245.6 CBZ29549.1 - 9.2e-05 22.8 0.0 0.00035 20.9 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 CBZ29549.1 - 0.00015 22.2 1.1 0.0018 18.7 0.1 2.4 2 0 0 2 2 2 1 AAA ATPase domain Viral_helicase1 PF01443.18 CBZ29549.1 - 0.00021 21.1 0.2 5.6 6.6 0.0 3.5 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase Herpes_Helicase PF02689.14 CBZ29549.1 - 0.00063 17.8 1.8 0.32 8.9 0.0 2.4 3 0 0 3 3 3 2 Helicase UvrD_C_2 PF13538.6 CBZ29549.1 - 0.00065 19.5 0.2 0.0032 17.3 0.0 2.3 2 0 0 2 2 2 1 UvrD-like helicase C-terminal domain AAA_22 PF13401.6 CBZ29549.1 - 0.0014 18.9 0.1 0.054 13.8 0.1 2.5 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.17 CBZ29549.1 - 0.0017 18.1 0.2 0.005 16.6 0.0 1.8 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_5 PF07728.14 CBZ29549.1 - 0.0047 16.9 0.1 0.22 11.5 0.1 2.4 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) Helicase_RecD PF05127.14 CBZ29549.1 - 0.012 15.5 0.3 1.4 8.7 0.4 2.4 2 0 0 2 2 2 0 Helicase Zeta_toxin PF06414.12 CBZ29549.1 - 0.019 14.3 0.1 0.033 13.5 0.1 1.3 1 0 0 1 1 1 0 Zeta toxin MeaB PF03308.16 CBZ29549.1 - 0.021 13.8 0.1 0.045 12.7 0.1 1.5 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB NACHT PF05729.12 CBZ29549.1 - 0.029 14.3 0.1 0.055 13.4 0.1 1.4 1 0 0 1 1 1 0 NACHT domain Bac_DnaA PF00308.18 CBZ29549.1 - 0.031 14.1 0.1 0.092 12.6 0.0 1.7 2 0 0 2 2 2 0 Bacterial dnaA protein ABC_tran PF00005.27 CBZ29549.1 - 0.053 14.0 1.4 0.089 13.3 0.5 1.7 2 0 0 2 2 1 0 ABC transporter NTPase_1 PF03266.15 CBZ29549.1 - 0.054 13.4 0.1 0.63 9.9 0.1 2.2 2 0 0 2 2 2 0 NTPase SH3_13 PF18335.1 CBZ29549.1 - 0.067 13.0 0.0 0.15 12.0 0.0 1.5 1 0 0 1 1 1 0 ATP-dependent RecD-like DNA helicase SH3 domain 4PPT_N PF17837.1 CBZ29549.1 - 0.082 13.0 0.1 0.19 11.9 0.1 1.6 1 0 0 1 1 1 0 4'-phosphopantetheinyl transferase N-terminal domain AAA_29 PF13555.6 CBZ29549.1 - 0.12 12.1 0.0 0.25 11.1 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain PhoH PF02562.16 CBZ29549.1 - 0.13 11.7 0.1 0.26 10.7 0.1 1.4 1 0 0 1 1 1 0 PhoH-like protein PIN_11 PF18479.1 CBZ29551.1 - 0.017 15.3 0.2 0.46 10.7 0.2 2.3 1 1 1 2 2 2 0 PIN like domain tRNA_deacylase PF04414.12 CBZ29552.1 - 0.088 12.3 0.1 0.19 11.2 0.1 1.5 1 0 0 1 1 1 0 D-aminoacyl-tRNA deacylase NAD_synthase PF02540.17 CBZ29557.1 - 1.3e-32 112.9 0.0 1.6e-32 112.6 0.0 1.1 1 0 0 1 1 1 1 NAD synthase Asn_synthase PF00733.21 CBZ29557.1 - 0.058 13.1 0.0 0.084 12.5 0.0 1.3 1 0 0 1 1 1 0 Asparagine synthase PAPS_reduct PF01507.19 CBZ29557.1 - 0.17 11.9 0.0 0.28 11.2 0.0 1.4 1 0 0 1 1 1 0 Phosphoadenosine phosphosulfate reductase family PP2C PF00481.21 CBZ29559.1 - 6.5e-68 229.1 0.0 1.1e-67 228.4 0.0 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C SpoU_methylase PF00588.19 CBZ29561.1 - 6.5e-09 36.1 0.2 0.013 15.7 0.0 4.0 4 0 0 4 4 4 3 SpoU rRNA Methylase family cwf21 PF08312.12 CBZ29561.1 - 0.16 12.1 0.0 0.34 11.1 0.0 1.6 1 1 0 1 1 1 0 cwf21 domain DNA_pol_E_B PF04042.16 CBZ29562.1 - 5e-12 45.6 0.1 7.6e-10 38.5 0.0 2.3 2 0 0 2 2 2 2 DNA polymerase alpha/epsilon subunit B Coatomer_E PF04733.14 CBZ29563.1 - 3.4e-30 105.5 5.8 1.4e-29 103.4 5.8 1.8 1 1 0 1 1 1 1 Coatomer epsilon subunit TPR_14 PF13428.6 CBZ29563.1 - 2.6e-05 24.7 9.2 0.37 11.7 1.0 5.3 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_2 PF07719.17 CBZ29563.1 - 3.2e-05 23.7 5.7 0.34 11.1 0.0 5.5 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_19 PF14559.6 CBZ29563.1 - 0.0011 19.4 5.4 0.37 11.3 1.1 3.5 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_10 PF13374.6 CBZ29563.1 - 0.0012 18.6 3.9 1.8 8.6 0.1 4.0 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.28 CBZ29563.1 - 0.0014 18.4 3.3 0.54 10.2 0.0 4.6 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_12 PF13424.6 CBZ29563.1 - 0.0016 18.7 10.2 0.006 16.9 2.2 4.7 5 1 1 6 6 6 2 Tetratricopeptide repeat TPR_16 PF13432.6 CBZ29563.1 - 0.0028 18.3 2.3 0.0028 18.3 2.3 4.4 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_8 PF13181.6 CBZ29563.1 - 0.0056 16.8 5.1 0.26 11.6 0.0 4.3 5 0 0 5 5 5 1 Tetratricopeptide repeat ANAPC3 PF12895.7 CBZ29563.1 - 0.22 11.8 4.3 2.9 8.2 0.6 3.7 3 2 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 CD225 PF04505.12 CBZ29563.1 - 0.49 10.6 4.7 0.84 9.8 0.0 3.2 4 0 0 4 4 4 0 Interferon-induced transmembrane protein TPR_7 PF13176.6 CBZ29563.1 - 1.3 9.3 3.5 21 5.4 0.1 4.2 5 0 0 5 5 5 0 Tetratricopeptide repeat WW PF00397.26 CBZ29564.1 - 1.6e-12 47.3 1.2 2.5e-12 46.6 1.2 1.4 1 0 0 1 1 1 1 WW domain zf-CCCH PF00642.24 CBZ29564.1 - 1.2e-05 25.0 0.7 1.2e-05 25.0 0.7 1.6 2 0 0 2 2 2 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 CBZ29564.1 - 0.00012 22.0 1.3 0.00028 20.8 1.3 1.6 1 0 0 1 1 1 1 Zinc finger domain zf-CCCH_4 PF18044.1 CBZ29564.1 - 0.0031 17.3 2.0 0.0038 17.0 0.7 1.8 2 0 0 2 2 2 1 CCCH-type zinc finger Torus PF16131.5 CBZ29564.1 - 0.0073 17.0 0.3 0.009 16.7 0.3 1.2 1 0 0 1 1 1 1 Torus domain zf-CCCH_2 PF14608.6 CBZ29564.1 - 0.13 12.8 0.5 0.13 12.8 0.5 1.8 2 0 0 2 2 2 0 RNA-binding, Nab2-type zinc finger PUF PF00806.19 CBZ29565.1 - 2.1e-23 80.6 0.0 0.012 15.3 0.0 8.9 9 0 0 9 9 9 7 Pumilio-family RNA binding repeat UTP15_C PF09384.10 CBZ29565.1 - 0.0048 16.6 3.4 0.37 10.5 0.1 2.8 2 0 0 2 2 2 2 UTP15 C terminal YbgS PF13985.6 CBZ29565.1 - 0.57 10.5 4.9 1.1 9.6 0.3 2.4 2 0 0 2 2 2 0 YbgS-like protein zf-RING_12 PF17976.1 CBZ29567.1 - 0.083 13.2 0.0 0.17 12.1 0.0 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain DUF959 PF06121.14 CBZ29570.1 - 0.059 13.6 0.1 0.094 13.0 0.1 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF959) Nop14 PF04147.12 CBZ29570.1 - 3 5.9 11.1 3.7 5.6 11.1 1.0 1 0 0 1 1 1 0 Nop14-like family Pkinase PF00069.25 CBZ29572.1 - 1.2e-45 156.0 0.0 2.7e-44 151.5 0.0 2.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ29572.1 - 4.5e-30 104.8 0.0 1.8e-29 102.8 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase PH PF00169.29 CBZ29572.1 - 2.5e-07 31.2 0.0 4.2e-07 30.4 0.0 1.4 1 0 0 1 1 1 1 PH domain PH_9 PF15410.6 CBZ29572.1 - 0.0028 18.0 0.0 0.0052 17.1 0.0 1.4 1 0 0 1 1 1 1 Pleckstrin homology domain Kinase-like PF14531.6 CBZ29572.1 - 0.0039 16.5 0.0 0.0068 15.8 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Sod_Fe_C PF02777.18 CBZ29573.1 - 9.5e-39 131.7 0.0 1.7e-38 130.9 0.0 1.4 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.22 CBZ29573.1 - 1.1e-18 67.5 1.2 1.4e-18 67.1 0.2 1.7 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, alpha-hairpin domain Sod_Fe_C PF02777.18 CBZ29574.1 - 9.3e-39 131.7 0.0 1.5e-38 131.0 0.0 1.3 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.22 CBZ29574.1 - 2.3e-18 66.4 1.7 2.5e-18 66.3 0.1 1.8 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, alpha-hairpin domain Ras PF00071.22 CBZ29575.1 - 8.2e-36 123.0 0.0 1e-35 122.8 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CBZ29575.1 - 6.1e-32 110.4 0.0 8.9e-32 109.8 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CBZ29575.1 - 3.1e-10 39.8 0.0 4e-10 39.4 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 CBZ29575.1 - 7.9e-07 28.7 0.0 1.3e-06 28.0 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 CBZ29575.1 - 1.1e-05 24.9 0.0 1.4e-05 24.6 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 CBZ29575.1 - 2.5e-05 23.9 0.0 0.0022 17.6 0.0 2.8 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 CBZ29575.1 - 3.8e-05 23.7 0.0 5.7e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase TniB PF05621.11 CBZ29575.1 - 0.00026 20.4 0.0 0.019 14.4 0.0 2.3 2 0 0 2 2 2 1 Bacterial TniB protein MMR_HSR1_Xtn PF16897.5 CBZ29575.1 - 0.00097 19.1 0.0 0.0017 18.3 0.0 1.4 1 0 0 1 1 1 1 C-terminal region of MMR_HSR1 domain RsgA_GTPase PF03193.16 CBZ29575.1 - 0.0023 17.9 0.0 2.4 8.0 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase ATP_bind_1 PF03029.17 CBZ29575.1 - 0.0024 17.7 0.0 0.0037 17.1 0.0 1.4 1 1 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_16 PF13191.6 CBZ29575.1 - 0.12 12.7 0.0 0.23 11.8 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain Cpn60_TCP1 PF00118.24 CBZ29576.1 - 2.1e-82 277.3 5.0 4.4e-82 276.3 5.0 1.5 1 1 0 1 1 1 1 TCP-1/cpn60 chaperonin family AKAP95 PF04988.12 CBZ29576.1 - 0.17 12.1 0.1 30 4.8 0.0 3.0 3 0 0 3 3 3 0 A-kinase anchoring protein 95 (AKAP95) Cation_efflux PF01545.21 CBZ29578.1 - 2.2e-05 24.3 6.3 4.6e-05 23.2 6.3 1.5 1 1 0 1 1 1 1 Cation efflux family CBFD_NFYB_HMF PF00808.23 CBZ29579.1 - 0.00098 19.4 0.0 0.0014 18.9 0.0 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone DNA_pol_A_exo1 PF01612.20 CBZ29580.1 - 1.7e-09 37.7 0.0 6.6e-09 35.7 0.0 1.8 1 1 0 1 1 1 1 3'-5' exonuclease Peptidase_C27 PF05407.12 CBZ29581.1 - 0.76 9.8 4.4 0.8 9.8 0.1 3.0 3 0 0 3 3 3 0 Rubella virus endopeptidase DUF647 PF04884.14 CBZ29584.1 - 5.8e-34 117.8 8.6 8.4e-34 117.3 8.6 1.2 1 0 0 1 1 1 1 Vitamin B6 photo-protection and homoeostasis DUF745 PF05335.13 CBZ29585.1 - 0.0078 15.9 4.1 0.0078 15.9 4.1 3.3 5 0 0 5 5 5 1 Protein of unknown function (DUF745) DnaJ_C PF01556.18 CBZ29586.1 - 5.5e-34 117.4 0.0 7.4e-34 117.0 0.0 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 CBZ29586.1 - 2.3e-15 56.4 0.7 4e-15 55.7 0.7 1.4 1 0 0 1 1 1 1 DnaJ domain Acyltransferase PF01553.21 CBZ29588.1 - 6.5e-15 54.9 0.1 2.2e-14 53.2 0.0 1.8 2 0 0 2 2 2 1 Acyltransferase Lipase_GDSL_3 PF14606.6 CBZ29588.1 - 0.18 11.9 0.0 0.32 11.1 0.0 1.3 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase family Ribo_biogen_C PF04034.13 CBZ29590.1 - 8.8e-50 167.7 0.0 1.2e-49 167.3 0.0 1.2 1 0 0 1 1 1 1 Ribosome biogenesis protein, C-terminal RLI PF04068.15 CBZ29590.1 - 1.6e-10 40.6 0.0 3.3e-10 39.6 0.0 1.5 1 0 0 1 1 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI DUF4200 PF13863.6 CBZ29592.1 - 6.8e-21 74.9 14.3 6.8e-21 74.9 14.3 3.8 3 0 0 3 3 3 2 Domain of unknown function (DUF4200) DUF2730 PF10805.8 CBZ29592.1 - 0.29 11.3 8.9 1.7 8.8 0.6 3.7 3 0 0 3 3 3 0 Protein of unknown function (DUF2730) NuA4 PF09340.10 CBZ29592.1 - 0.35 10.8 5.2 0.11 12.4 0.3 2.7 2 1 0 2 2 2 0 Histone acetyltransferase subunit NuA4 DUF5398 PF17376.2 CBZ29592.1 - 0.41 11.3 0.1 0.41 11.3 0.1 2.9 3 0 0 3 3 3 0 Family of unknown function (DUF5398) COG2 PF06148.11 CBZ29592.1 - 5.9 7.0 12.9 8.2 6.5 2.3 3.7 2 1 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Endosulfine PF04667.17 CBZ29593.1 - 1.2e-06 28.5 0.5 1.7e-06 28.1 0.5 1.3 1 0 0 1 1 1 1 cAMP-regulated phosphoprotein/endosulfine conserved region DUF3456 PF11938.8 CBZ29594.1 - 6.9e-28 98.1 1.0 4.5e-27 95.5 0.1 2.0 2 0 0 2 2 2 1 TLR4 regulator and MIR-interacting MSAP MIR PF02815.19 CBZ29595.1 - 0.077 12.8 0.0 0.12 12.2 0.0 1.3 1 0 0 1 1 1 0 MIR domain EMP24_GP25L PF01105.24 CBZ29596.1 - 2.3e-31 109.2 0.0 2.5e-31 109.0 0.0 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Ras PF00071.22 CBZ29597.1 - 2.1e-60 203.0 0.0 2.4e-60 202.8 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CBZ29597.1 - 4.9e-33 113.9 0.0 8.3e-33 113.2 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CBZ29597.1 - 2.2e-12 46.8 0.0 2.6e-12 46.5 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 CBZ29597.1 - 0.00025 21.1 0.0 0.00055 20.0 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 CBZ29597.1 - 0.00035 20.5 0.0 0.2 11.5 0.0 2.6 2 1 1 3 3 3 2 RsgA GTPase GTP_EFTU PF00009.27 CBZ29597.1 - 0.00039 20.0 0.0 0.0017 18.0 0.0 1.9 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 CBZ29597.1 - 0.001 18.5 0.0 0.0015 17.9 0.0 1.3 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_22 PF13401.6 CBZ29597.1 - 0.027 14.7 0.1 0.074 13.3 0.1 2.1 1 1 0 1 1 1 0 AAA domain DAP3 PF10236.9 CBZ29597.1 - 0.038 13.2 0.0 0.061 12.5 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 AAA_29 PF13555.6 CBZ29597.1 - 0.099 12.4 0.0 0.26 11.1 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_24 PF13479.6 CBZ29597.1 - 0.11 12.2 0.0 0.16 11.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain TetR_C_16 PF17920.1 CBZ29597.1 - 0.14 12.4 0.0 0.23 11.7 0.0 1.3 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain DUF5617 PF18493.1 CBZ29599.1 - 0.00042 20.4 0.0 0.0006 19.9 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF5617) ABC_tran PF00005.27 CBZ29600.1 - 1.1e-17 64.8 0.0 2.1e-17 63.9 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 CBZ29600.1 - 4.6e-09 36.5 0.3 4.4e-05 23.4 0.3 2.2 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 CBZ29600.1 - 9.7e-07 28.4 0.0 5.1e-06 26.1 0.0 2.0 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain ABC_membrane PF00664.23 CBZ29600.1 - 1.8e-05 24.5 6.2 3.5e-05 23.6 6.2 1.4 1 0 0 1 1 1 1 ABC transporter transmembrane region RsgA_GTPase PF03193.16 CBZ29600.1 - 0.00065 19.6 0.1 0.0023 17.9 0.1 1.9 2 0 0 2 2 2 1 RsgA GTPase AAA_16 PF13191.6 CBZ29600.1 - 0.0016 18.8 0.2 0.006 17.0 0.2 2.1 1 1 0 1 1 1 1 AAA ATPase domain AAA PF00004.29 CBZ29600.1 - 0.0043 17.5 0.4 0.24 11.8 0.0 3.2 4 0 0 4 4 3 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 CBZ29600.1 - 0.0044 17.3 1.8 0.032 14.5 1.8 2.4 1 1 0 1 1 1 1 AAA domain AAA_23 PF13476.6 CBZ29600.1 - 0.014 15.9 0.0 0.023 15.2 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_15 PF13175.6 CBZ29600.1 - 0.022 14.5 0.0 1 9.0 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain Rad17 PF03215.15 CBZ29600.1 - 0.036 14.0 0.1 0.078 12.9 0.1 1.5 1 0 0 1 1 1 0 Rad17 P-loop domain Adeno_IVa2 PF02456.15 CBZ29600.1 - 0.046 12.5 0.0 0.073 11.9 0.0 1.2 1 0 0 1 1 1 0 Adenovirus IVa2 protein AAA_25 PF13481.6 CBZ29600.1 - 0.049 13.2 0.6 0.38 10.3 0.1 2.3 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 CBZ29600.1 - 0.054 13.2 0.1 0.12 12.1 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain RNA_helicase PF00910.22 CBZ29600.1 - 0.068 13.6 0.0 0.13 12.6 0.0 1.5 1 0 0 1 1 1 0 RNA helicase NACHT PF05729.12 CBZ29600.1 - 0.12 12.3 0.0 9.5 6.1 0.0 2.7 2 0 0 2 2 2 0 NACHT domain ATPase_2 PF01637.18 CBZ29600.1 - 0.24 11.3 0.1 0.51 10.2 0.1 1.5 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea CTP_transf_like PF01467.26 CBZ29601.1 - 3.7e-07 30.4 0.0 7.5e-07 29.4 0.0 1.5 1 0 0 1 1 1 1 Cytidylyltransferase-like FAD_syn PF06574.12 CBZ29601.1 - 0.058 13.3 0.0 0.1 12.5 0.0 1.4 1 0 0 1 1 1 0 FAD synthetase dCMP_cyt_deam_1 PF00383.23 CBZ29602.1 - 2.7e-07 30.4 0.0 8e-07 28.9 0.0 1.9 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 CBZ29602.1 - 3.3e-06 26.9 0.0 6.4e-06 26.0 0.0 1.4 1 0 0 1 1 1 1 MafB19-like deaminase Bd3614-deam PF14439.6 CBZ29602.1 - 0.0019 18.3 0.1 0.0071 16.4 0.0 2.0 2 0 0 2 2 2 1 Bd3614-like deaminase Cons_hypoth95 PF03602.15 CBZ29603.1 - 0.084 12.5 0.0 0.28 10.8 0.0 1.8 2 0 0 2 2 2 0 Conserved hypothetical protein 95 MAD PF05557.13 CBZ29604.1 - 0.063 11.7 22.0 0.047 12.1 18.0 2.0 2 0 0 2 2 2 0 Mitotic checkpoint protein TMPIT PF07851.13 CBZ29604.1 - 0.22 10.8 3.4 0.47 9.6 3.4 1.5 1 0 0 1 1 1 0 TMPIT-like protein KLRAQ PF10205.9 CBZ29604.1 - 0.52 10.6 0.1 0.52 10.6 0.1 4.2 3 1 0 4 4 4 0 Predicted coiled-coil domain-containing protein Fungal_TACC PF12709.7 CBZ29604.1 - 1.2 9.6 13.4 7.6 7.1 0.1 4.2 3 1 2 5 5 5 0 Fungal Transforming acidic coiled-coil (TACC) proteins baeRF_family7 PF18849.1 CBZ29605.1 - 0.016 15.4 0.0 0.089 13.0 0.0 2.1 2 0 0 2 2 2 0 Bacterial archaeo-eukaryotic release factor family 7 RRM_1 PF00076.22 CBZ29607.1 - 3.2e-09 36.5 0.0 5.5e-09 35.7 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CSTF2_hinge PF14327.6 CBZ29607.1 - 0.00028 21.3 0.1 0.00085 19.7 0.1 1.8 1 0 0 1 1 1 1 Hinge domain of cleavage stimulation factor subunit 2 Nup35_RRM_2 PF14605.6 CBZ29607.1 - 0.03 14.3 0.1 0.054 13.5 0.1 1.4 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif Importin_rep_4 PF18808.1 CBZ29609.1 - 2.1e-17 63.2 2.9 3e-13 49.9 0.0 4.1 4 0 0 4 4 4 2 Importin repeat HEAT_EZ PF13513.6 CBZ29609.1 - 1.6e-09 38.1 4.8 0.48 11.0 0.0 6.3 5 0 0 5 5 5 3 HEAT-like repeat HEAT PF02985.22 CBZ29609.1 - 3.1e-08 33.2 9.8 0.35 11.2 0.5 6.9 6 0 0 6 6 6 3 HEAT repeat Cnd1 PF12717.7 CBZ29609.1 - 3.5e-06 27.2 0.5 0.00024 21.2 0.0 2.9 2 0 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 CBZ29609.1 - 1.5e-05 25.3 0.5 0.0046 17.3 0.1 4.5 4 1 2 6 6 6 2 HEAT repeats RTP1_C1 PF10363.9 CBZ29609.1 - 0.0011 19.1 3.0 0.5 10.6 0.0 4.4 4 1 0 4 4 4 1 Required for nuclear transport of RNA pol II C-terminus 1 DUF3385 PF11865.8 CBZ29609.1 - 0.0075 16.2 0.2 0.43 10.5 0.0 3.3 2 0 0 2 2 2 1 Domain of unknown function (DUF3385) DUF4487 PF14868.6 CBZ29609.1 - 0.012 14.4 0.4 0.76 8.5 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4487) Synaptobrevin PF00957.21 CBZ29611.1 - 4.9e-09 35.9 4.4 1e-08 34.8 4.4 1.4 1 0 0 1 1 1 1 Synaptobrevin CSN8_PSD8_EIF3K PF10075.9 CBZ29613.1 - 7.6e-15 55.1 0.1 1.4e-14 54.3 0.0 1.4 2 0 0 2 2 2 1 CSN8/PSMD8/EIF3K family PCI PF01399.27 CBZ29613.1 - 0.0022 18.4 0.0 0.0034 17.9 0.0 1.4 1 0 0 1 1 1 1 PCI domain FPL PF09758.9 CBZ29613.1 - 0.082 12.9 0.0 0.13 12.3 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised conserved protein GTP_EFTU PF00009.27 CBZ29615.1 - 3.7e-24 85.3 0.0 6.6e-24 84.5 0.0 1.5 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.24 CBZ29615.1 - 1.9e-16 59.8 0.0 4e-16 58.8 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.6 CBZ29615.1 - 8e-08 32.3 0.0 1.7e-07 31.2 0.0 1.5 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_IV PF03764.18 CBZ29615.1 - 6.9e-07 29.1 0.0 1.6e-06 27.9 0.0 1.5 1 0 0 1 1 1 1 Elongation factor G, domain IV MMR_HSR1 PF01926.23 CBZ29615.1 - 5.9e-06 26.3 0.0 1e-05 25.5 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 CBZ29615.1 - 0.00013 22.1 0.1 0.035 14.1 0.0 2.3 1 1 1 2 2 2 2 Dynamin family Septin PF00735.18 CBZ29615.1 - 0.0061 15.9 0.0 0.01 15.2 0.0 1.2 1 0 0 1 1 1 1 Septin Roc PF08477.13 CBZ29615.1 - 0.0071 16.6 0.0 0.014 15.6 0.0 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 CBZ29615.1 - 0.0092 15.4 0.0 0.015 14.7 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit EFTUD2 PF16004.5 CBZ29615.1 - 0.48 11.0 2.6 5.7 7.5 0.2 2.3 1 1 1 2 2 2 0 116 kDa U5 small nuclear ribonucleoprotein component N-terminus Complex1_LYR PF05347.15 CBZ29616.1 - 6.7e-13 48.5 0.5 1.4e-12 47.4 0.5 1.6 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.6 CBZ29616.1 - 0.0014 19.2 0.3 0.0028 18.2 0.3 1.6 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR_2 PF13233.6 CBZ29616.1 - 3.8 8.3 6.5 72 4.2 6.5 2.3 1 1 0 1 1 1 0 Complex1_LYR-like Spc7 PF08317.11 CBZ29617.1 - 0.00026 20.0 18.5 0.00026 20.0 18.5 9.3 3 2 8 11 11 11 2 Spc7 kinetochore protein TMF_TATA_bd PF12325.8 CBZ29617.1 - 0.0035 17.5 5.9 0.0035 17.5 5.9 13.7 4 3 9 13 13 13 2 TATA element modulatory factor 1 TATA binding DEAD PF00270.29 CBZ29618.1 - 8.3e-41 139.7 0.0 1.7e-40 138.6 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CBZ29618.1 - 9.5e-24 83.9 0.0 2.2e-23 82.7 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 CBZ29618.1 - 9.7e-14 51.4 0.2 3e-13 49.8 0.2 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.15 CBZ29618.1 - 0.022 14.8 0.0 0.051 13.6 0.0 1.6 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit CENP-B_dimeris PF09026.10 CBZ29618.1 - 3.1 8.2 8.5 0.12 12.8 0.8 2.5 3 0 0 3 3 3 0 Centromere protein B dimerisation domain Formyl_trans_N PF00551.19 CBZ29619.1 - 2.1e-16 60.2 0.0 4.1e-16 59.2 0.0 1.4 1 0 0 1 1 1 1 Formyl transferase CS PF04969.16 CBZ29621.1 - 0.046 14.7 0.0 0.046 14.7 0.0 1.7 2 0 0 2 2 2 0 CS domain CCDC66 PF15236.6 CBZ29622.1 - 1.3e-15 57.5 487.7 1.2 9.0 16.6 23.0 1 1 33 34 34 34 33 Coiled-coil domain-containing protein 66 Nif11 PF07862.11 CBZ29623.1 - 0.19 12.1 0.0 0.34 11.3 0.0 1.4 1 0 0 1 1 1 0 Nif11 domain DUF3450 PF11932.8 CBZ29625.1 - 0.2 11.0 3.8 0.39 10.0 3.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) DUF4482 PF14818.6 CBZ29625.1 - 0.22 12.4 4.0 0.12 13.3 1.6 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4482) DASH_Spc19 PF08287.11 CBZ29625.1 - 0.97 9.3 7.1 1.1 9.1 4.9 1.9 2 0 0 2 2 2 0 Spc19 ERG4_ERG24 PF01222.17 CBZ29627.1 - 1.8e-125 419.1 1.9 2.1e-125 418.9 1.9 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF1295 PF06966.12 CBZ29627.1 - 6.1e-08 32.5 0.2 1.8e-07 31.0 0.2 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF1295) PEMT PF04191.13 CBZ29627.1 - 9.3e-05 22.8 0.1 0.00039 20.8 0.0 2.1 2 0 0 2 2 2 1 Phospholipid methyltransferase ICMT PF04140.14 CBZ29627.1 - 0.003 17.9 0.0 0.003 17.9 0.0 3.1 4 0 0 4 4 4 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family NAD_binding_1 PF00175.21 CBZ29629.1 - 8.4e-19 68.2 0.0 1.7e-16 60.8 0.0 2.3 1 1 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 CBZ29629.1 - 2.8e-13 50.0 0.0 4.5e-13 49.4 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.12 CBZ29629.1 - 0.00024 21.2 0.0 0.0014 18.8 0.0 1.9 1 1 0 1 1 1 1 Ferric reductase NAD binding domain Nsp1_C PF05064.13 CBZ29630.1 - 2.9e-09 36.7 1.5 4.7e-09 36.1 1.5 1.2 1 0 0 1 1 1 1 Nsp1-like C-terminal region Lipoprotein_20 PF13942.6 CBZ29630.1 - 0.086 12.7 1.6 0.12 12.2 1.6 1.1 1 0 0 1 1 1 0 YfhG lipoprotein Mut7-C PF01927.16 CBZ29630.1 - 0.15 12.2 1.0 0.24 11.5 1.0 1.2 1 0 0 1 1 1 0 Mut7-C RNAse domain DUF724 PF05266.14 CBZ29630.1 - 0.43 10.4 1.5 0.63 9.8 1.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF724) FlxA PF14282.6 CBZ29630.1 - 1.4 9.0 5.0 2.7 8.0 5.0 1.4 1 0 0 1 1 1 0 FlxA-like protein MIP PF00230.20 CBZ29632.1 - 7.6e-35 120.7 16.3 9.4e-35 120.4 16.3 1.0 1 0 0 1 1 1 1 Major intrinsic protein MIP PF00230.20 CBZ29633.1 - 2.9e-30 105.7 14.5 4.2e-30 105.1 14.5 1.2 1 0 0 1 1 1 1 Major intrinsic protein DUF4692 PF15763.5 CBZ29633.1 - 1.3 9.5 7.1 8.5 6.8 4.3 2.2 1 1 1 2 2 2 0 Regulator of human erythroid cell expansion (RHEX) DNA_pol_lambd_f PF10391.9 CBZ29635.1 - 0.003 17.4 0.0 0.0069 16.2 0.0 1.6 1 0 0 1 1 1 1 Fingers domain of DNA polymerase lambda HAD_2 PF13419.6 CBZ29635.1 - 0.19 11.8 0.0 1.9 8.5 0.0 2.4 2 1 0 2 2 2 0 Haloacid dehalogenase-like hydrolase Kelch_6 PF13964.6 CBZ29636.1 - 7.2e-07 29.3 0.2 0.0049 17.1 0.1 3.8 3 0 0 3 3 3 2 Kelch motif Kelch_5 PF13854.6 CBZ29636.1 - 2.3e-06 27.5 2.7 0.058 13.4 0.4 3.5 3 0 0 3 3 3 2 Kelch motif Kelch_1 PF01344.25 CBZ29636.1 - 2.8e-06 26.8 0.6 2.9e-05 23.6 0.4 2.7 3 0 0 3 3 3 1 Kelch motif Kelch_4 PF13418.6 CBZ29636.1 - 7.9e-06 25.8 0.2 0.015 15.3 0.0 4.2 4 0 0 4 4 4 1 Galactose oxidase, central domain Kelch_3 PF13415.6 CBZ29636.1 - 0.013 15.8 2.2 0.24 11.7 0.0 3.5 3 0 0 3 3 3 0 Galactose oxidase, central domain Kelch_2 PF07646.15 CBZ29636.1 - 0.015 15.3 2.5 0.25 11.4 0.6 3.1 3 0 0 3 3 3 0 Kelch motif TPR_12 PF13424.6 CBZ29637.1 - 2.9e-07 30.7 4.5 2.9e-07 30.7 4.5 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.28 CBZ29637.1 - 0.0017 18.1 9.8 3.2 7.7 0.2 4.2 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.17 CBZ29637.1 - 0.0019 18.2 13.1 0.29 11.3 1.0 4.5 4 0 0 4 4 4 2 Tetratricopeptide repeat DHR10 PF18595.1 CBZ29637.1 - 0.12 12.4 2.1 0.5 10.4 2.1 2.0 1 0 0 1 1 1 0 Designed helical repeat protein 10 domain TPR_10 PF13374.6 CBZ29637.1 - 0.13 12.1 6.4 0.13 12.2 0.2 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.6 CBZ29637.1 - 0.22 11.6 8.7 0.31 11.2 0.1 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat MIT PF04212.18 CBZ29637.1 - 0.56 10.3 7.8 0.086 12.9 1.5 2.8 3 0 0 3 3 3 0 MIT (microtubule interacting and transport) domain TPR_8 PF13181.6 CBZ29637.1 - 2.3 8.7 7.0 11 6.5 0.2 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat Methyltr_RsmB-F PF01189.17 CBZ29639.1 - 7.4e-30 104.1 0.0 1.1e-29 103.5 0.0 1.2 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F DUF3123 PF11321.8 CBZ29639.1 - 0.065 13.9 0.2 0.18 12.5 0.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3123) MTS PF05175.14 CBZ29639.1 - 0.095 12.2 0.0 0.19 11.3 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain NUDIX PF00293.28 CBZ29640.1 - 0.003 17.6 0.0 0.0059 16.6 0.0 1.6 1 0 0 1 1 1 1 NUDIX domain PAP_assoc PF03828.19 CBZ29641.1 - 1.1e-08 35.2 0.0 2e-08 34.3 0.0 1.5 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.23 CBZ29641.1 - 0.0085 16.4 0.0 0.017 15.4 0.0 1.5 1 0 0 1 1 1 1 Nucleotidyltransferase domain Polbeta PF18765.1 CBZ29641.1 - 0.18 11.9 0.0 0.31 11.1 0.0 1.4 1 0 0 1 1 1 0 Polymerase beta, Nucleotidyltransferase Glyoxalase PF00903.25 CBZ29642.1 - 0.2 11.8 0.1 0.51 10.5 0.1 1.7 1 0 0 1 1 1 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily TPR_14 PF13428.6 CBZ29644.1 - 6.1e-07 29.7 43.6 0.38 11.7 0.1 11.3 8 2 2 10 10 10 4 Tetratricopeptide repeat TPR_17 PF13431.6 CBZ29644.1 - 0.00045 20.4 0.7 7.6 7.2 0.1 4.7 3 0 0 3 3 3 1 Tetratricopeptide repeat PRP1_N PF06424.12 CBZ29644.1 - 0.00049 20.5 1.5 0.0011 19.3 1.5 1.6 1 0 0 1 1 1 1 PRP1 splicing factor, N-terminal TPR_2 PF07719.17 CBZ29644.1 - 0.0047 16.9 1.7 0.0047 16.9 1.7 4.6 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_1 PF00515.28 CBZ29644.1 - 0.02 14.7 1.2 0.28 11.1 1.6 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat ANAPC3 PF12895.7 CBZ29644.1 - 0.024 14.9 1.5 0.13 12.5 0.4 2.5 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 CAMSAP_CC1 PF17095.5 CBZ29644.1 - 0.12 12.3 0.8 0.36 10.7 0.8 1.8 1 0 0 1 1 1 0 Spectrin-binding region of Ca2+-Calmodulin TPR_8 PF13181.6 CBZ29644.1 - 1.2 9.6 4.1 19 5.8 1.2 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_11 PF13414.6 CBZ29644.1 - 3.8 7.3 5.9 36 4.2 3.1 2.7 2 0 0 2 2 2 0 TPR repeat TPR_12 PF13424.6 CBZ29644.1 - 4.1 7.7 17.1 0.21 11.9 1.1 5.1 5 0 0 5 5 5 0 Tetratricopeptide repeat cNMP_binding PF00027.29 CBZ29648.1 - 1.4e-10 41.0 0.0 0.0008 19.4 0.0 5.3 4 1 0 4 4 4 3 Cyclic nucleotide-binding domain HD PF01966.22 CBZ29649.1 - 1.3e-07 31.8 0.0 5.3e-07 29.9 0.0 2.2 1 0 0 1 1 1 1 HD domain A_deaminase PF00962.22 CBZ29650.1 - 1.3e-92 310.6 0.1 2.3e-69 234.2 0.0 2.4 2 0 0 2 2 2 2 Adenosine/AMP deaminase DUF2525 PF10733.9 CBZ29650.1 - 0.17 12.1 0.1 0.43 10.9 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2525) DUF1192 PF06698.11 CBZ29650.1 - 0.23 11.6 0.4 0.87 9.7 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) Ctr PF04145.15 CBZ29651.1 - 0.018 15.7 1.5 0.11 13.2 0.5 2.7 2 1 0 2 2 2 0 Ctr copper transporter family 7TMR-HDED PF07697.11 CBZ29652.1 - 0.081 13.0 0.0 0.21 11.7 0.0 1.6 1 0 0 1 1 1 0 7TM-HD extracellular ANAPC4_WD40 PF12894.7 CBZ29653.1 - 0.18 12.1 0.1 5.7 7.3 0.0 3.1 1 1 2 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain CHCH PF06747.13 CBZ29654.1 - 0.0028 17.7 3.1 0.0044 17.1 3.1 1.3 1 0 0 1 1 1 1 CHCH domain DUF1054 PF06335.12 CBZ29656.1 - 0.56 10.1 0.0 0.56 10.1 0.0 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1054) ECH_2 PF16113.5 CBZ29656.1 - 0.77 9.2 6.7 7.8 5.9 1.4 2.6 2 0 0 2 2 2 0 Enoyl-CoA hydratase/isomerase zf-HIT PF04438.16 CBZ29656.1 - 3.4 7.6 5.9 12 5.8 5.9 2.0 1 0 0 1 1 1 0 HIT zinc finger Complex1_LYR PF05347.15 CBZ29657.1 - 0.00026 21.0 0.7 0.00095 19.2 0.7 1.9 1 1 0 1 1 1 1 Complex 1 protein (LYR family) Sod_Fe_C PF02777.18 CBZ29658.1 - 3e-31 107.6 1.3 4.8e-31 107.0 0.3 1.9 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.22 CBZ29658.1 - 6.4e-19 68.2 0.1 1.4e-18 67.1 0.1 1.6 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain Cys_Met_Meta_PP PF01053.20 CBZ29659.1 - 2e-93 313.0 0.0 2.3e-93 312.8 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 CBZ29659.1 - 3.3e-07 29.8 0.0 5e-07 29.2 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 CBZ29659.1 - 0.005 16.2 0.0 0.0086 15.4 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.17 CBZ29659.1 - 0.0077 15.6 0.0 0.024 13.9 0.0 1.7 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.19 CBZ29659.1 - 0.016 14.2 0.0 0.024 13.6 0.0 1.1 1 0 0 1 1 1 0 Aminotransferase class-V HyaE PF07449.11 CBZ29659.1 - 0.066 13.2 0.0 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 Hydrogenase-1 expression protein HyaE SpoU_methylase PF00588.19 CBZ29660.1 - 5e-24 85.1 0.1 9.5e-23 80.9 0.0 3.2 4 0 0 4 4 4 1 SpoU rRNA Methylase family Aa_trans PF01490.18 CBZ29661.1 - 5.3e-52 176.9 29.1 6.6e-52 176.6 29.1 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 CBZ29661.1 - 4.5e-10 39.1 8.1 4.5e-10 39.1 8.1 1.7 1 1 0 1 1 1 1 Tryptophan/tyrosine permease family Mur_ligase PF01225.25 CBZ29662.1 - 0.078 13.3 0.4 4.5 7.7 0.0 3.1 2 1 1 3 3 3 0 Mur ligase family, catalytic domain DUF1539 PF07560.11 CBZ29662.1 - 0.22 11.6 0.6 1.1 9.3 0.3 2.2 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1539) VASt PF16016.5 CBZ29663.1 - 2e-09 38.1 0.0 3.7e-09 37.1 0.0 1.4 1 0 0 1 1 1 1 VAD1 Analog of StAR-related lipid transfer domain Ribosomal_L27e PF01777.18 CBZ29664.1 - 1.3e-24 86.3 1.7 2e-24 85.7 1.7 1.3 1 0 0 1 1 1 1 Ribosomal L27e protein family KOW PF00467.29 CBZ29664.1 - 3.2e-05 23.7 0.8 3.2e-05 23.7 0.8 1.7 2 0 0 2 2 2 1 KOW motif DUF3446 PF11928.8 CBZ29665.1 - 1 9.7 5.0 0.69 10.3 1.4 2.7 2 0 0 2 2 2 0 Early growth response N-terminal domain Ribosomal_L27e PF01777.18 CBZ29666.1 - 3.1e-24 85.1 1.2 4.9e-24 84.5 1.2 1.3 1 0 0 1 1 1 1 Ribosomal L27e protein family KOW PF00467.29 CBZ29666.1 - 3.2e-05 23.7 0.8 3.2e-05 23.7 0.8 1.7 2 0 0 2 2 2 1 KOW motif Sybindin PF04099.12 CBZ29667.1 - 3.6e-22 78.8 0.0 4.3e-22 78.6 0.0 1.0 1 0 0 1 1 1 1 Sybindin-like family Sedlin_N PF04628.13 CBZ29667.1 - 1.4e-06 28.5 0.0 1.5e-06 28.3 0.0 1.2 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Rhodanese PF00581.20 CBZ29669.1 - 5.1e-08 33.4 0.0 7.2e-08 32.9 0.0 1.3 1 0 0 1 1 1 1 Rhodanese-like domain Sec7 PF01369.20 CBZ29670.1 - 1.2e-19 70.7 0.0 1.8e-19 70.1 0.0 1.3 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.7 CBZ29670.1 - 8.4e-19 68.0 1.6 1.2e-18 67.5 0.1 2.0 2 0 0 2 2 2 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF3138 PF11336.8 CBZ29671.1 - 1.3 7.6 8.5 0.091 11.4 1.9 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3138) RNase_T PF00929.24 CBZ29674.1 - 4.7e-19 69.5 0.1 1.4e-15 58.2 0.1 2.9 1 1 0 1 1 1 1 Exonuclease DUF5051 PF16473.5 CBZ29674.1 - 0.14 12.1 0.5 0.27 11.2 0.0 1.6 2 0 0 2 2 2 0 3' exoribonuclease, RNase T-like DNA_pol_A_exo1 PF01612.20 CBZ29674.1 - 0.2 11.3 0.0 0.95 9.1 0.0 1.8 2 0 0 2 2 2 0 3'-5' exonuclease Cylicin_N PF15241.6 CBZ29675.1 - 0.036 14.2 0.6 0.065 13.4 0.6 1.3 1 0 0 1 1 1 0 Cylicin N-terminus RRM_1 PF00076.22 CBZ29676.1 - 3.3e-20 71.7 0.0 1.3e-06 28.1 0.0 4.0 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_Rrp7 PF17799.1 CBZ29676.1 - 0.03 14.1 0.9 0.087 12.6 0.0 2.2 3 0 0 3 3 3 0 Rrp7 RRM-like N-terminal domain RPN7 PF10602.9 CBZ29677.1 - 3.7e-49 166.8 0.4 9.5e-49 165.4 0.0 1.8 2 0 0 2 2 2 1 26S proteasome subunit RPN7 PCI PF01399.27 CBZ29677.1 - 1.6e-15 57.5 0.3 4.3e-15 56.1 0.0 1.9 3 0 0 3 3 3 1 PCI domain IFT46_B_C PF12317.8 CBZ29677.1 - 0.022 14.5 0.0 0.047 13.4 0.0 1.5 1 0 0 1 1 1 0 Intraflagellar transport complex B protein 46 C terminal Prefoldin PF02996.17 CBZ29679.1 - 1.4e-10 41.2 0.3 2.6e-10 40.2 0.3 1.5 1 0 0 1 1 1 1 Prefoldin subunit Prefoldin_3 PF13758.6 CBZ29679.1 - 2.4e-06 27.5 2.8 0.00032 20.7 0.2 2.3 2 0 0 2 2 2 2 Prefoldin subunit TPR_2 PF07719.17 CBZ29680.1 - 1.6e-07 30.9 23.0 0.05 13.7 0.4 6.4 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_1 PF00515.28 CBZ29680.1 - 3.8e-07 29.7 18.8 0.15 11.9 0.1 6.3 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_16 PF13432.6 CBZ29680.1 - 9.3e-07 29.4 0.8 9.3e-07 29.4 0.8 5.1 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_19 PF14559.6 CBZ29680.1 - 9.4e-07 29.3 9.8 0.00034 21.1 0.8 5.0 4 1 0 4 4 4 2 Tetratricopeptide repeat CS PF04969.16 CBZ29680.1 - 2.3e-06 28.5 0.1 6.1e-06 27.2 0.1 1.8 2 0 0 2 2 1 1 CS domain Fis1_TPR_C PF14853.6 CBZ29680.1 - 0.0068 16.5 7.7 0.94 9.6 0.1 4.2 4 0 0 4 4 4 2 Fis1 C-terminal tetratricopeptide repeat ANAPC3 PF12895.7 CBZ29680.1 - 0.017 15.3 9.2 3.8 7.8 0.4 3.8 3 0 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 Phage_lysozyme PF00959.19 CBZ29680.1 - 0.12 12.9 1.3 1.5 9.3 0.1 2.6 2 0 0 2 2 2 0 Phage lysozyme TPR_12 PF13424.6 CBZ29680.1 - 0.13 12.6 21.2 1.1 9.6 0.3 5.6 5 1 1 6 6 6 0 Tetratricopeptide repeat TPPII_N PF12583.8 CBZ29680.1 - 0.46 11.1 8.1 0.63 10.6 0.1 3.0 2 0 0 2 2 2 0 Tripeptidyl peptidase II N terminal TPR_14 PF13428.6 CBZ29680.1 - 0.59 11.1 25.0 2.8 9.0 0.1 6.9 5 2 2 7 7 7 0 Tetratricopeptide repeat TPR_7 PF13176.6 CBZ29680.1 - 1.5 9.0 17.4 29 5.0 0.2 6.0 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_10 PF13374.6 CBZ29680.1 - 2.4 8.2 0.0 2.4 8.2 0.0 4.6 5 0 0 5 5 5 0 Tetratricopeptide repeat FYVE PF01363.21 CBZ29681.1 - 0.073 13.2 14.5 0.16 12.1 14.5 1.5 1 0 0 1 1 1 0 FYVE zinc finger CTP_transf_1 PF01148.20 CBZ29682.1 - 6.9e-30 104.7 14.2 1.5e-29 103.6 1.4 3.4 4 0 0 4 4 4 2 Cytidylyltransferase family DUF778 PF05608.12 CBZ29683.1 - 6.2e-70 235.4 0.7 8.5e-70 235.0 0.0 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF778) SNAP PF14938.6 CBZ29685.1 - 4.3e-54 183.8 18.5 5e-54 183.6 18.5 1.0 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP TPR_MalT PF17874.1 CBZ29685.1 - 0.00053 19.5 6.5 0.00071 19.0 6.5 1.4 1 0 0 1 1 1 1 MalT-like TPR region TPR_14 PF13428.6 CBZ29685.1 - 0.00061 20.4 16.7 1.3 10.1 0.3 5.3 3 1 2 5 5 5 3 Tetratricopeptide repeat Foie-gras_1 PF11817.8 CBZ29685.1 - 0.0035 17.0 5.3 0.0091 15.6 5.3 1.7 1 1 0 1 1 1 1 Foie gras liver health family 1 TPR_12 PF13424.6 CBZ29685.1 - 0.0038 17.5 10.1 0.99 9.7 0.5 3.5 2 2 1 3 3 3 3 Tetratricopeptide repeat Alkyl_sulf_dimr PF14863.6 CBZ29685.1 - 0.0081 16.6 7.2 0.24 11.8 0.1 2.8 1 1 1 2 2 2 1 Alkyl sulfatase dimerisation TPR_19 PF14559.6 CBZ29685.1 - 0.012 16.1 12.7 1.1 9.8 0.7 2.9 2 1 0 2 2 2 0 Tetratricopeptide repeat ToxS PF17323.2 CBZ29685.1 - 0.078 12.6 0.1 0.13 12.0 0.1 1.3 1 0 0 1 1 1 0 Trans-membrane regulatory protein ToxS ANAPC3 PF12895.7 CBZ29685.1 - 0.16 12.2 4.3 0.4 11.0 1.3 2.9 1 1 2 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 DUF2379 PF09543.10 CBZ29685.1 - 0.25 11.5 5.9 7 6.9 0.3 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2379) DUF3043 PF11241.8 CBZ29685.1 - 1.2 9.1 5.8 0.71 9.9 2.8 1.9 1 1 0 2 2 2 0 Protein of unknown function (DUF3043) TPR_10 PF13374.6 CBZ29685.1 - 1.6 8.7 5.9 21 5.1 0.2 4.3 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_4 PF07721.14 CBZ29685.1 - 3.3 8.6 7.7 25 5.9 0.3 4.6 4 1 0 4 4 3 0 Tetratricopeptide repeat AvrM_N PF18247.1 CBZ29685.1 - 4.9 7.2 9.5 31 4.6 0.1 3.9 1 1 2 3 3 3 0 Flax-rust effector AvrM N-terminal domain DUF3450 PF11932.8 CBZ29686.1 - 0.0052 16.1 1.5 0.0052 16.1 1.5 4.1 2 1 0 3 3 3 1 Protein of unknown function (DUF3450) Fib_alpha PF08702.10 CBZ29686.1 - 0.049 13.8 0.4 0.049 13.8 0.4 4.3 4 1 1 5 5 5 0 Fibrinogen alpha/beta chain family FlaC_arch PF05377.11 CBZ29686.1 - 2.4 8.6 11.1 34 4.9 0.1 5.5 5 0 0 5 5 5 0 Flagella accessory protein C (FlaC) V_ATPase_I PF01496.19 CBZ29686.1 - 2.7 5.8 23.1 0.31 8.9 6.9 3.2 2 1 1 3 3 3 0 V-type ATPase 116kDa subunit family DUF1664 PF07889.12 CBZ29686.1 - 5.9 6.9 19.1 0.24 11.5 1.2 4.4 3 1 1 4 4 4 0 Protein of unknown function (DUF1664) UCH PF00443.29 CBZ29687.1 - 4.5e-50 170.5 0.0 7.4e-50 169.8 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 CBZ29687.1 - 1.9e-13 50.7 0.9 1.7e-07 31.1 0.0 3.2 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase DUSP PF06337.12 CBZ29687.1 - 0.16 12.6 0.0 0.37 11.4 0.0 1.5 1 0 0 1 1 1 0 DUSP domain PQQ_2 PF13360.6 CBZ29688.1 - 0.00053 19.6 1.1 0.64 9.6 0.1 2.7 2 1 0 2 2 2 2 PQQ-like domain FG-GAP PF01839.23 CBZ29688.1 - 0.0017 18.4 0.2 0.0057 16.8 0.2 1.9 1 0 0 1 1 1 1 FG-GAP repeat VCBS PF13517.6 CBZ29688.1 - 0.029 15.0 0.2 0.18 12.4 0.2 2.4 1 1 0 1 1 1 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella PQQ PF01011.21 CBZ29688.1 - 0.34 10.9 1.9 2.5 8.2 0.1 3.0 3 0 0 3 3 3 0 PQQ enzyme repeat TTL PF03133.15 CBZ29689.1 - 3.4e-68 229.9 0.0 2.8e-56 190.8 0.0 2.1 1 1 1 2 2 2 2 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 CBZ29689.1 - 1.1e-07 31.3 0.0 0.00079 18.7 0.0 2.2 2 0 0 2 2 2 2 YheC/D like ATP-grasp DUF1738 PF08401.11 CBZ29690.1 - 0.00048 20.2 0.0 1.1 9.4 0.0 3.4 3 0 0 3 3 3 2 Domain of unknown function (DUF1738) NDK PF00334.19 CBZ29691.1 - 3.1e-56 189.1 0.0 3.5e-56 188.9 0.0 1.0 1 0 0 1 1 1 1 Nucleoside diphosphate kinase NDK PF00334.19 CBZ29692.1 - 3.1e-56 189.1 0.0 3.5e-56 188.9 0.0 1.0 1 0 0 1 1 1 1 Nucleoside diphosphate kinase MCM PF00493.23 CBZ29693.1 - 1.2e-97 325.4 0.0 1.8e-97 324.9 0.0 1.2 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 CBZ29693.1 - 6.8e-27 93.8 1.8 1.4e-26 92.8 1.8 1.5 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 CBZ29693.1 - 4.3e-21 75.1 0.1 1.4e-20 73.4 0.1 2.0 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 CBZ29693.1 - 6.5e-09 36.3 0.0 1.7e-08 35.0 0.0 1.7 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 CBZ29693.1 - 6.4e-07 29.0 0.0 9.1e-05 21.9 0.0 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 CBZ29693.1 - 6.2e-06 26.3 0.0 3.5e-05 23.8 0.0 2.4 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_lid_2 PF17863.1 CBZ29693.1 - 0.0015 18.3 0.5 0.0043 16.8 0.5 1.9 1 0 0 1 1 1 1 AAA lid domain AAA_3 PF07726.11 CBZ29693.1 - 0.012 15.5 0.0 0.032 14.1 0.0 1.8 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) HisKA PF00512.25 CBZ29693.1 - 0.014 15.4 0.0 0.74 9.9 0.0 2.7 2 0 0 2 2 2 0 His Kinase A (phospho-acceptor) domain Sigma54_activat PF00158.26 CBZ29693.1 - 0.14 11.9 0.0 0.84 9.3 0.0 2.1 1 1 0 1 1 1 0 Sigma-54 interaction domain TBCA PF02970.16 CBZ29694.1 - 8.1e-17 61.3 2.0 1.1e-16 60.9 2.0 1.1 1 0 0 1 1 1 1 Tubulin binding cofactor A Spc7 PF08317.11 CBZ29694.1 - 0.017 14.0 1.2 0.02 13.8 1.2 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein AAA_30 PF13604.6 CBZ29694.1 - 0.035 13.8 0.1 0.053 13.2 0.1 1.4 1 0 0 1 1 1 0 AAA domain Phosducin PF02114.16 CBZ29695.1 - 4.4e-11 42.2 0.1 5.1e-11 42.0 0.1 1.0 1 0 0 1 1 1 1 Phosducin Thioredoxin PF00085.20 CBZ29695.1 - 9.9e-09 35.1 0.0 1.5e-08 34.6 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin TraF PF13728.6 CBZ29695.1 - 0.0027 17.6 0.0 0.0048 16.8 0.0 1.4 1 1 0 1 1 1 1 F plasmid transfer operon protein Thioredoxin_3 PF13192.6 CBZ29695.1 - 0.028 14.5 0.0 0.061 13.4 0.0 1.6 1 0 0 1 1 1 0 Thioredoxin domain MnmE_helical PF12631.7 CBZ29695.1 - 0.033 14.3 0.1 0.033 14.3 0.1 1.1 1 0 0 1 1 1 0 MnmE helical domain S1-like PF14444.6 CBZ29695.1 - 0.12 12.3 0.3 0.25 11.3 0.3 1.5 1 0 0 1 1 1 0 S1-like Rab5ip PF07019.12 CBZ29698.1 - 1.2e-18 67.5 6.4 1.4e-18 67.3 6.4 1.1 1 0 0 1 1 1 1 Rab5-interacting protein (Rab5ip) DUF21 PF01595.20 CBZ29700.1 - 8.9e-36 123.2 0.8 1.3e-35 122.7 0.8 1.2 1 0 0 1 1 1 1 Cyclin M transmembrane N-terminal domain DUF4453 PF14627.6 CBZ29700.1 - 0.1 12.7 0.0 0.26 11.4 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4453) L_HMGIC_fpl PF10242.9 CBZ29700.1 - 0.31 11.2 5.2 0.13 12.5 1.1 2.0 2 0 0 2 2 2 0 Lipoma HMGIC fusion partner-like protein LRR_4 PF12799.7 CBZ29701.1 - 1.2e-16 60.5 9.5 2.7e-08 34.0 1.9 3.7 2 1 1 3 3 3 3 Leucine Rich repeats (2 copies) AMPK1_CBM PF16561.5 CBZ29701.1 - 1e-13 51.3 0.0 2.2e-13 50.2 0.0 1.6 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase SCAB-Ig PF16709.5 CBZ29701.1 - 1.3e-12 47.6 0.1 0.00018 21.5 0.0 4.9 5 0 0 5 5 5 3 Ig domain of plant-specific actin-binding protein LRR_9 PF14580.6 CBZ29701.1 - 2.3e-10 40.2 0.1 9.5e-08 31.7 0.0 2.3 1 1 1 2 2 2 2 Leucine-rich repeat LRR_8 PF13855.6 CBZ29701.1 - 2.4e-09 36.8 7.9 0.00016 21.3 1.3 3.4 2 1 2 4 4 4 3 Leucine rich repeat LRR_1 PF00560.33 CBZ29701.1 - 0.0089 16.4 1.2 53 4.9 0.2 4.3 3 1 0 3 3 3 0 Leucine Rich Repeat LRR_6 PF13516.6 CBZ29701.1 - 0.022 14.8 11.5 9.4 6.6 0.8 5.0 5 0 0 5 5 5 0 Leucine Rich repeat CBM_48 PF02922.18 CBZ29701.1 - 0.039 14.3 0.1 0.43 11.0 0.0 2.6 2 0 0 2 2 2 0 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) RicinB_lectin_2 PF14200.6 CBZ29701.1 - 0.082 13.6 0.4 23 5.8 0.0 3.1 3 0 0 3 3 3 0 Ricin-type beta-trefoil lectin domain-like MMR_HSR1 PF01926.23 CBZ29702.1 - 8.6e-13 48.4 0.0 2.1e-12 47.1 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 CBZ29702.1 - 5.3e-07 29.7 0.5 2.9e-05 24.0 0.0 2.8 3 0 0 3 3 3 1 RsgA GTPase GTP_EFTU PF00009.27 CBZ29702.1 - 0.0016 18.0 0.0 0.39 10.2 0.0 2.8 2 1 0 2 2 2 2 Elongation factor Tu GTP binding domain ABC_tran PF00005.27 CBZ29702.1 - 0.022 15.3 0.1 0.1 13.1 0.0 2.1 2 0 0 2 2 2 0 ABC transporter AAA_16 PF13191.6 CBZ29702.1 - 0.026 14.9 0.2 0.11 12.8 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain DnaJ PF00226.31 CBZ29703.1 - 2.1e-20 72.6 0.0 4.4e-20 71.6 0.0 1.5 1 0 0 1 1 1 1 DnaJ domain DUF4407 PF14362.6 CBZ29703.1 - 0.17 11.2 1.2 0.28 10.5 1.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Metallophos PF00149.28 CBZ29704.1 - 1.6e-36 126.7 0.1 2.2e-36 126.3 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 CBZ29704.1 - 0.022 15.2 0.1 0.046 14.2 0.1 1.5 1 0 0 1 1 1 0 Serine-threonine protein phosphatase N-terminal domain Roc PF08477.13 CBZ29705.1 - 9.6e-14 51.6 0.0 1.9e-13 50.7 0.0 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 CBZ29705.1 - 4.6e-11 42.6 0.1 1.1e-10 41.4 0.1 1.5 1 1 0 1 1 1 1 Ras family COR PF16095.5 CBZ29705.1 - 8.9e-08 32.2 0.1 0.0022 17.8 0.0 2.3 2 0 0 2 2 2 2 C-terminal of Roc, COR, domain Gtr1_RagA PF04670.12 CBZ29705.1 - 0.00014 21.3 0.0 0.00022 20.6 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region IBR PF01485.21 CBZ29705.1 - 0.00041 20.5 0.5 0.00094 19.4 0.5 1.5 1 0 0 1 1 1 1 IBR domain, a half RING-finger domain YdjO PF14169.6 CBZ29705.1 - 0.032 14.0 0.4 0.064 13.0 0.4 1.4 1 0 0 1 1 1 0 Cold-inducible protein YdjO Zn_Tnp_IS1 PF03811.13 CBZ29705.1 - 0.067 12.9 0.2 0.28 11.0 0.2 2.1 2 0 0 2 2 2 0 InsA N-terminal domain DUF3082 PF11282.8 CBZ29707.1 - 0.011 16.0 1.6 0.019 15.2 1.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3082) zf-MIZ PF02891.20 CBZ29708.1 - 9e-11 41.3 6.0 1.8e-10 40.4 6.0 1.6 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger zf-Nse PF11789.8 CBZ29708.1 - 3.7e-06 26.7 1.6 8.5e-06 25.5 1.6 1.7 1 1 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit DZR PF12773.7 CBZ29708.1 - 0.24 11.4 0.1 0.24 11.4 0.1 2.6 2 1 0 2 2 2 0 Double zinc ribbon zf-NADH-PPase PF09297.11 CBZ29708.1 - 0.85 9.3 9.9 0.096 12.4 4.5 2.3 2 0 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain ABC_tran PF00005.27 CBZ29709.1 - 3.3e-34 118.3 0.0 1.6e-33 116.1 0.0 2.1 2 0 0 2 2 2 1 ABC transporter ABC_membrane PF00664.23 CBZ29709.1 - 1.5e-33 116.6 7.1 2e-33 116.2 7.1 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region SMC_N PF02463.19 CBZ29709.1 - 2.6e-05 23.8 0.2 0.0074 15.7 0.0 2.4 1 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 CBZ29709.1 - 0.00095 19.6 0.0 0.0023 18.4 0.0 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 CBZ29709.1 - 0.0014 18.4 1.3 0.013 15.2 0.1 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 CBZ29709.1 - 0.0035 17.2 0.0 0.0075 16.2 0.0 1.5 1 0 0 1 1 1 1 RsgA GTPase AAA_22 PF13401.6 CBZ29709.1 - 0.0068 16.7 0.1 0.11 12.7 0.1 2.6 1 1 0 1 1 1 1 AAA domain AAA_23 PF13476.6 CBZ29709.1 - 0.022 15.2 0.3 0.14 12.7 0.3 2.0 1 1 1 2 2 2 0 AAA domain AAA_21 PF13304.6 CBZ29709.1 - 0.049 13.4 0.0 0.094 12.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system MMR_HSR1 PF01926.23 CBZ29709.1 - 0.08 13.0 0.0 0.44 10.6 0.0 2.2 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_33 PF13671.6 CBZ29709.1 - 0.12 12.6 0.0 0.36 11.0 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 CBZ29709.1 - 0.12 11.9 0.0 0.24 10.9 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region Pox_A31 PF05771.11 CBZ29709.1 - 0.14 12.1 0.1 0.36 10.8 0.1 1.7 1 0 0 1 1 1 0 Poxvirus A31 protein MAGE_N PF12440.8 CBZ29711.1 - 5.5 7.7 15.7 2.6 8.8 1.9 3.0 2 1 0 2 2 2 0 Melanoma associated antigen family N terminal FSH1 PF03959.13 CBZ29712.1 - 3.5e-29 102.0 0.0 5.4e-29 101.4 0.0 1.3 1 0 0 1 1 1 1 Serine hydrolase (FSH1) MMR_HSR1_C PF08438.10 CBZ29712.1 - 5.5e-26 91.3 0.0 1.8e-25 89.7 0.0 1.9 2 0 0 2 2 2 1 GTPase of unknown function C-terminal MMR_HSR1 PF01926.23 CBZ29712.1 - 4e-15 55.9 0.0 1.7e-14 53.9 0.0 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 CBZ29712.1 - 0.00067 19.2 0.1 0.006 16.1 0.0 2.2 2 0 0 2 2 2 1 Ferrous iron transport protein B RWD PF05773.22 CBZ29712.1 - 0.0015 18.8 0.0 0.0035 17.6 0.0 1.6 1 0 0 1 1 1 1 RWD domain Hydrolase_4 PF12146.8 CBZ29712.1 - 0.021 14.1 0.6 0.23 10.7 0.0 2.5 1 1 1 2 2 2 0 Serine aminopeptidase, S33 MeaB PF03308.16 CBZ29712.1 - 0.076 12.0 0.1 0.43 9.5 0.1 2.0 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB ATP_bind_1 PF03029.17 CBZ29712.1 - 0.09 12.5 0.1 5.1 6.8 0.0 2.4 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein Ribosomal_L3 PF00297.22 CBZ29713.1 - 5.3e-149 496.2 9.1 6.1e-149 496.0 9.1 1.0 1 0 0 1 1 1 1 Ribosomal protein L3 Aldedh PF00171.22 CBZ29714.1 - 1.5e-17 63.3 0.6 6.1e-13 48.1 0.1 2.4 2 0 0 2 2 2 2 Aldehyde dehydrogenase family IQ PF00612.27 CBZ29715.1 - 1.5e-25 86.5 105.8 4.3e-05 22.9 3.8 13.2 12 0 0 12 12 12 10 IQ calmodulin-binding motif TPR_10 PF13374.6 CBZ29715.1 - 0.0053 16.6 0.0 0.0053 16.6 0.0 7.1 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_2 PF07719.17 CBZ29715.1 - 0.0071 16.4 0.0 6 7.2 0.0 4.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.6 CBZ29715.1 - 0.076 13.1 2.4 5.5 7.3 0.0 5.1 3 1 1 4 4 4 0 Tetratricopeptide repeat LRR_6 PF13516.6 CBZ29716.1 - 2.4e-07 30.3 9.2 0.023 14.7 0.2 4.5 5 0 0 5 5 5 3 Leucine Rich repeat LRR_4 PF12799.7 CBZ29716.1 - 4.8e-06 26.8 1.0 0.00073 19.9 1.6 3.2 3 0 0 3 3 3 1 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CBZ29716.1 - 0.011 15.5 2.1 0.05 13.4 1.5 2.4 3 0 0 3 3 3 0 Leucine rich repeat LRR_1 PF00560.33 CBZ29716.1 - 0.3 11.8 1.9 9.9 7.2 0.0 3.6 4 0 0 4 4 4 0 Leucine Rich Repeat L51_S25_CI-B8 PF05047.16 CBZ29717.1 - 0.0065 16.4 0.1 0.0098 15.8 0.1 1.3 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain COG5 PF10392.9 CBZ29719.1 - 4.2e-15 56.1 18.5 6e-13 49.1 4.6 3.8 2 1 1 3 3 3 2 Golgi transport complex subunit 5 DUF1664 PF07889.12 CBZ29719.1 - 0.0043 17.1 3.3 0.0051 16.8 1.3 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF1664) GGDEF_2 PF17853.1 CBZ29719.1 - 0.015 15.5 0.4 0.17 12.1 0.0 3.2 2 1 0 2 2 2 0 GGDEF-like domain Dor1 PF04124.12 CBZ29719.1 - 0.037 12.7 6.1 0.034 12.8 4.0 2.0 2 0 0 2 2 2 0 Dor1-like family COG2 PF06148.11 CBZ29719.1 - 3.3 7.8 7.1 1.5 8.9 3.1 2.6 3 0 0 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 Roc PF08477.13 CBZ29721.1 - 2.9e-08 33.9 0.2 2e-07 31.3 0.2 2.0 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CBZ29721.1 - 1.2e-05 24.8 0.2 0.001 18.6 0.2 2.3 1 1 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.20 CBZ29721.1 - 3.4e-05 23.2 0.1 0.048 12.8 0.0 2.2 1 1 1 2 2 2 2 G-protein alpha subunit Ras PF00071.22 CBZ29721.1 - 9e-05 22.1 0.0 0.00031 20.4 0.0 1.8 2 1 0 2 2 2 1 Ras family MMR_HSR1 PF01926.23 CBZ29721.1 - 0.00059 19.9 0.1 0.00094 19.2 0.1 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 CBZ29721.1 - 0.0034 17.0 0.0 0.0053 16.3 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain PduV-EutP PF10662.9 CBZ29721.1 - 0.008 15.9 0.0 0.02 14.7 0.0 1.7 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation SRPRB PF09439.10 CBZ29721.1 - 0.036 13.5 0.2 0.058 12.8 0.2 1.6 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit Dynamin_N PF00350.23 CBZ29721.1 - 0.071 13.2 0.1 0.14 12.2 0.1 1.5 1 1 0 1 1 1 0 Dynamin family AAA_18 PF13238.6 CBZ29721.1 - 0.072 13.6 0.0 0.14 12.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain T2SSE PF00437.20 CBZ29721.1 - 0.077 12.0 0.1 0.1 11.6 0.1 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_16 PF13191.6 CBZ29723.1 - 9.1e-08 32.7 0.0 2.3e-07 31.4 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain Roc PF08477.13 CBZ29723.1 - 4e-06 27.0 0.1 1.8e-05 25.0 0.0 2.0 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase AAA_22 PF13401.6 CBZ29723.1 - 2.1e-05 24.8 0.3 0.00085 19.6 0.3 2.8 1 1 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 CBZ29723.1 - 0.00026 20.9 0.3 0.058 13.3 0.6 2.8 1 1 1 2 2 2 1 RsgA GTPase GTP_EFTU PF00009.27 CBZ29723.1 - 0.00039 20.0 0.0 1.2 8.6 0.0 2.8 3 0 0 3 3 3 2 Elongation factor Tu GTP binding domain NACHT PF05729.12 CBZ29723.1 - 0.0012 18.8 0.0 0.0042 17.0 0.0 1.9 2 0 0 2 2 2 1 NACHT domain ABC_tran PF00005.27 CBZ29723.1 - 0.0034 17.9 0.1 0.0062 17.1 0.1 1.6 1 1 0 1 1 1 1 ABC transporter G-alpha PF00503.20 CBZ29723.1 - 0.0059 15.8 0.0 0.067 12.3 0.0 2.1 2 0 0 2 2 2 1 G-protein alpha subunit AAA_33 PF13671.6 CBZ29723.1 - 0.007 16.5 1.3 0.074 13.2 0.1 2.9 3 0 0 3 3 3 1 AAA domain cobW PF02492.19 CBZ29723.1 - 0.008 15.8 0.2 0.089 12.4 0.2 2.2 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_29 PF13555.6 CBZ29723.1 - 0.0083 15.8 0.0 0.018 14.8 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain ATP_bind_1 PF03029.17 CBZ29723.1 - 0.01 15.7 0.4 0.47 10.2 0.3 2.2 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein FtsK_SpoIIIE PF01580.18 CBZ29723.1 - 0.011 15.1 0.0 0.022 14.1 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family NB-ARC PF00931.22 CBZ29723.1 - 0.017 14.3 0.0 0.03 13.5 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain MobB PF03205.14 CBZ29723.1 - 0.027 14.4 0.0 0.059 13.3 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Zeta_toxin PF06414.12 CBZ29723.1 - 0.027 13.8 0.1 0.14 11.4 0.0 2.1 1 1 1 2 2 2 0 Zeta toxin AAA_19 PF13245.6 CBZ29723.1 - 0.037 14.4 0.0 0.065 13.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 CBZ29723.1 - 0.038 13.7 0.1 0.24 11.1 0.0 2.3 3 0 0 3 3 2 0 AAA domain Pox_A32 PF04665.12 CBZ29723.1 - 0.041 13.3 0.0 0.096 12.1 0.0 1.5 2 0 0 2 2 1 0 Poxvirus A32 protein T2SSE PF00437.20 CBZ29723.1 - 0.046 12.8 0.2 0.094 11.8 0.2 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein Arf PF00025.21 CBZ29723.1 - 0.047 13.1 0.0 0.39 10.2 0.0 2.0 2 0 0 2 2 2 0 ADP-ribosylation factor family AAA_15 PF13175.6 CBZ29723.1 - 0.067 12.9 0.0 0.09 12.5 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain DAP3 PF10236.9 CBZ29723.1 - 0.073 12.2 0.0 0.12 11.5 0.0 1.4 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 ATPase_2 PF01637.18 CBZ29723.1 - 0.086 12.7 0.0 0.14 12.0 0.0 1.6 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_30 PF13604.6 CBZ29723.1 - 0.088 12.5 0.0 0.15 11.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain Ras PF00071.22 CBZ29723.1 - 0.092 12.3 0.0 0.58 9.8 0.0 2.1 2 0 0 2 2 2 0 Ras family Septin PF00735.18 CBZ29723.1 - 0.094 12.0 0.0 0.16 11.2 0.0 1.4 1 0 0 1 1 1 0 Septin SRPRB PF09439.10 CBZ29723.1 - 0.11 11.9 0.0 0.2 11.1 0.0 1.4 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit PRK PF00485.18 CBZ29723.1 - 0.11 12.2 0.0 0.19 11.5 0.0 1.3 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family PIF1 PF05970.14 CBZ29723.1 - 0.15 11.2 0.0 0.24 10.5 0.0 1.2 1 0 0 1 1 1 0 PIF1-like helicase NTPase_1 PF03266.15 CBZ29723.1 - 0.18 11.7 0.0 0.34 10.8 0.0 1.4 1 0 0 1 1 1 0 NTPase DLIC PF05783.11 CBZ29723.1 - 0.85 8.4 7.3 0.072 11.9 0.1 2.3 2 1 0 3 3 2 0 Dynein light intermediate chain (DLIC) Pkinase PF00069.25 CBZ29725.1 - 4.7e-75 252.3 0.0 7.2e-75 251.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ29725.1 - 4.6e-35 121.2 0.0 2.3e-34 118.8 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.22 CBZ29725.1 - 0.0027 17.4 0.1 0.0048 16.5 0.1 1.3 1 0 0 1 1 1 1 RIO1 family Kinase-like PF14531.6 CBZ29725.1 - 0.0091 15.3 0.7 0.018 14.4 0.0 1.7 3 0 0 3 3 3 1 Kinase-like FTA2 PF13095.6 CBZ29725.1 - 0.016 14.8 0.0 6.6 6.3 0.0 2.3 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Seadorna_VP7 PF07387.11 CBZ29725.1 - 0.025 13.7 0.0 0.04 13.0 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Haspin_kinase PF12330.8 CBZ29725.1 - 0.041 12.8 0.1 0.09 11.7 0.1 1.5 1 0 0 1 1 1 0 Haspin like kinase domain Glucosamine_iso PF01182.20 CBZ29726.1 - 3.7e-20 72.8 0.0 4.6e-20 72.5 0.0 1.1 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase Cpn60_TCP1 PF00118.24 CBZ29727.1 - 9.6e-147 489.5 10.8 1.1e-146 489.4 10.8 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Se-cys_synth_N PF12390.8 CBZ29728.1 - 0.073 13.3 1.0 0.37 11.1 0.5 2.5 2 0 0 2 2 2 0 Selenocysteine synthase N terminal MotA_ExbB PF01618.16 CBZ29729.1 - 1.2 8.8 0.0 1.2 8.8 0.0 2.6 3 0 0 3 3 3 0 MotA/TolQ/ExbB proton channel family DnaJ_C PF01556.18 CBZ29730.1 - 6.1e-27 94.5 0.0 8.1e-27 94.1 0.0 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 CBZ29730.1 - 3.6e-17 62.3 6.2 5.4e-17 61.7 6.2 1.3 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 CBZ29730.1 - 1.4e-11 44.5 13.7 2.4e-11 43.8 13.7 1.4 1 0 0 1 1 1 1 DnaJ central domain Anti-TRAP PF15777.5 CBZ29730.1 - 1.1e-06 28.5 8.7 0.00046 20.1 0.5 2.5 2 0 0 2 2 2 2 Tryptophan RNA-binding attenuator protein inhibitory protein DZR PF12773.7 CBZ29730.1 - 0.044 13.8 7.4 0.24 11.4 7.4 2.0 1 1 0 1 1 1 0 Double zinc ribbon Zn-ribbon_8 PF09723.10 CBZ29730.1 - 0.63 10.2 10.1 0.2 11.8 1.5 3.3 2 1 1 3 3 3 0 Zinc ribbon domain HypA PF01155.19 CBZ29730.1 - 1.3 9.1 8.2 18 5.4 1.1 2.4 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DUF3797 PF12677.7 CBZ29730.1 - 2.4 8.1 5.0 4.8 7.2 0.0 3.2 4 0 0 4 4 4 0 Domain of unknown function (DUF3797) Ribosomal_L32p PF01783.23 CBZ29730.1 - 3.6 7.9 10.8 0.091 13.0 1.0 3.0 2 1 1 3 3 3 0 Ribosomal L32p protein family Pyr_redox_2 PF07992.14 CBZ29731.1 - 1.8e-67 227.7 10.6 3.2e-67 226.9 6.5 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 CBZ29731.1 - 2.3e-39 134.0 0.5 5.6e-39 132.8 0.5 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 CBZ29731.1 - 1.9e-18 66.8 10.6 4.8e-17 62.3 1.3 3.1 3 1 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 CBZ29731.1 - 8.7e-14 51.5 8.5 1.7e-11 44.0 0.1 2.5 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 CBZ29731.1 - 7.7e-13 48.3 3.4 8.9e-11 41.5 0.2 2.5 2 0 0 2 2 2 2 Glucose inhibited division protein A FAD_oxidored PF12831.7 CBZ29731.1 - 6.3e-10 39.0 0.9 6.3e-10 39.0 0.9 3.3 3 1 1 4 4 4 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 CBZ29731.1 - 8.7e-08 32.3 4.4 4.2e-05 23.7 0.8 2.6 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 CBZ29731.1 - 9.5e-07 28.2 1.1 9.5e-07 28.2 1.1 3.5 2 1 2 4 4 4 1 FAD binding domain Thi4 PF01946.17 CBZ29731.1 - 1.1e-05 24.8 1.2 0.00018 20.9 0.1 2.4 2 0 0 2 2 2 1 Thi4 family FAD_binding_3 PF01494.19 CBZ29731.1 - 1.7e-05 24.3 13.2 0.02 14.2 0.6 3.2 2 1 1 3 3 3 3 FAD binding domain K_oxygenase PF13434.6 CBZ29731.1 - 2.2e-05 23.8 0.3 0.0056 15.9 0.0 2.7 2 1 1 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) AlaDh_PNT_C PF01262.21 CBZ29731.1 - 0.00012 21.5 9.4 0.0046 16.3 0.5 3.1 3 1 1 4 4 4 2 Alanine dehydrogenase/PNT, C-terminal domain HI0933_like PF03486.14 CBZ29731.1 - 0.00047 19.0 1.1 0.00047 19.0 1.1 3.7 3 1 1 4 4 4 1 HI0933-like protein 3HCDH_N PF02737.18 CBZ29731.1 - 0.0032 17.4 0.7 0.0032 17.4 0.7 2.9 2 1 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain XdhC_C PF13478.6 CBZ29731.1 - 0.05 14.1 0.2 1.4 9.4 0.0 2.4 2 0 0 2 2 2 0 XdhC Rossmann domain DAO PF01266.24 CBZ29731.1 - 0.052 13.1 13.0 0.63 9.6 1.1 3.3 3 1 1 4 4 4 0 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 CBZ29731.1 - 0.072 12.1 1.0 3.3 6.6 0.1 2.8 3 0 0 3 3 3 0 Lycopene cyclase protein UDPG_MGDP_dh_N PF03721.14 CBZ29731.1 - 0.26 10.8 3.6 0.23 11.0 0.2 2.3 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NAD_binding_7 PF13241.6 CBZ29731.1 - 0.37 11.2 4.1 1.5 9.3 0.9 2.8 2 1 0 2 2 2 0 Putative NAD(P)-binding Cyclin_N PF00134.23 CBZ29732.1 - 1e-38 132.0 3.6 3.9e-38 130.1 1.1 2.1 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 CBZ29732.1 - 1.1e-31 109.4 0.2 5.7e-31 107.1 0.0 2.1 2 0 0 2 2 2 1 Cyclin, C-terminal domain Cyclin_C_2 PF16899.5 CBZ29732.1 - 0.012 16.0 0.3 0.085 13.3 0.2 2.2 1 1 1 2 2 2 0 Cyclin C-terminal domain Na_H_antiporter PF03553.14 CBZ29733.1 - 0.076 12.2 0.0 0.086 12.1 0.0 1.0 1 0 0 1 1 1 0 Na+/H+ antiporter family TMEMspv1-c74-12 PF11044.8 CBZ29733.1 - 0.086 12.8 1.2 0.13 12.2 0.4 1.8 2 0 0 2 2 2 0 Plectrovirus spv1-c74 ORF 12 transmembrane protein Bac_export_2 PF01312.19 CBZ29733.1 - 0.12 11.6 0.1 0.14 11.3 0.1 1.1 1 0 0 1 1 1 0 FlhB HrpN YscU SpaS Family zf-B_box PF00643.24 CBZ29735.1 - 6.1e-07 29.5 3.4 1.7e-06 28.0 3.4 1.8 1 0 0 1 1 1 1 B-box zinc finger FAA_hydro_N_2 PF18288.1 CBZ29735.1 - 0.17 12.3 2.9 0.31 11.5 1.6 2.2 1 1 0 1 1 1 0 Fumarylacetoacetase N-terminal domain 2 Exonuc_VII_L PF02601.15 CBZ29735.1 - 0.27 10.8 5.9 0.13 11.8 3.1 1.9 2 0 0 2 2 2 0 Exonuclease VII, large subunit Lipase_3 PF01764.25 CBZ29736.1 - 9.8e-10 38.5 0.0 4.6e-09 36.3 0.0 2.1 2 0 0 2 2 2 1 Lipase (class 3) Hydrolase_4 PF12146.8 CBZ29736.1 - 0.023 14.0 0.2 0.047 13.0 0.2 1.4 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Voltage_CLC PF00654.20 CBZ29737.1 - 2.6e-80 270.3 24.7 2.6e-80 270.3 24.7 1.8 2 0 0 2 2 2 1 Voltage gated chloride channel CBS PF00571.28 CBZ29737.1 - 5e-08 33.3 0.2 0.00047 20.5 0.0 2.7 2 0 0 2 2 2 2 CBS domain KRTDAP PF15200.6 CBZ29737.1 - 0.07 12.9 0.0 0.17 11.7 0.0 1.6 1 0 0 1 1 1 0 Keratinocyte differentiation-associated TruD PF01142.18 CBZ29738.1 - 7.9e-29 100.7 0.0 8.9e-24 84.1 0.0 2.3 2 0 0 2 2 2 2 tRNA pseudouridine synthase D (TruD) zf-MYND PF01753.18 CBZ29739.1 - 0.0068 16.5 13.3 0.0068 16.5 13.3 2.4 2 0 0 2 2 2 1 MYND finger zf-Mss51 PF13824.6 CBZ29739.1 - 0.031 14.4 9.0 0.031 14.4 6.6 2.2 2 0 0 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 zf-C2H2_4 PF13894.6 CBZ29739.1 - 1.3 10.0 10.3 6.9 7.8 10.3 2.3 1 0 0 1 1 1 0 C2H2-type zinc finger Abhydrolase_1 PF00561.20 CBZ29740.1 - 5.4e-05 23.0 0.0 0.00011 22.0 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Dopey_N PF04118.14 CBZ29741.1 - 2.4e-38 132.0 0.0 1.1e-37 129.8 0.0 2.0 1 1 0 1 1 1 1 Dopey, N-terminal Cytochrom_B_N_2 PF13631.6 CBZ29742.1 - 0.38 10.7 6.8 0.89 9.5 0.6 2.8 2 0 0 2 2 2 0 Cytochrome b(N-terminal)/b6/petB UPF0564 PF10595.9 CBZ29743.1 - 1.7e-13 50.4 19.3 4.8e-10 39.0 1.4 3.4 3 1 1 4 4 4 2 Uncharacterised protein family UPF0564 DUF4913 PF16259.5 CBZ29743.1 - 0.13 12.3 1.6 9.4 6.4 0.3 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4913) AP1AR PF15745.5 CBZ29743.1 - 1.3 8.6 7.4 2.8 7.5 7.4 1.5 1 0 0 1 1 1 0 AP-1 complex-associated regulatory protein UPF0564 PF10595.9 CBZ29744.1 - 1.2e-14 54.2 15.7 2.1e-10 40.2 0.7 3.1 3 1 0 3 3 3 2 Uncharacterised protein family UPF0564 FAM101 PF15068.6 CBZ29744.1 - 7.8 6.4 6.7 2.2 8.2 0.3 3.2 3 1 1 4 4 4 0 FAM101 family zf-C2HC_2 PF13913.6 CBZ29746.1 - 2.4e-25 87.9 14.3 6.6e-10 38.7 0.5 3.5 3 0 0 3 3 3 3 zinc-finger of a C2HC-type zinc_ribbon_2 PF13240.6 CBZ29746.1 - 0.0057 16.3 8.1 0.0057 16.3 8.1 3.9 3 0 0 3 3 3 1 zinc-ribbon domain DZR PF12773.7 CBZ29746.1 - 0.059 13.4 15.0 0.046 13.8 2.9 4.2 4 0 0 4 4 4 0 Double zinc ribbon zf-C2H2_4 PF13894.6 CBZ29746.1 - 0.074 13.9 13.0 0.71 10.9 0.4 4.1 4 0 0 4 4 3 0 C2H2-type zinc finger zf_UBZ PF18439.1 CBZ29746.1 - 0.25 11.0 8.7 9 6.0 0.0 4.0 3 1 1 4 4 4 0 Ubiquitin-Binding Zinc Finger zf-RING_7 PF02591.15 CBZ29746.1 - 0.35 11.1 11.1 1.7 8.9 0.0 4.1 3 1 0 3 3 3 0 C4-type zinc ribbon domain zf-CHCC PF10276.9 CBZ29746.1 - 0.35 10.9 3.7 3.2 7.9 0.2 3.6 3 0 0 3 3 3 0 Zinc-finger domain Rad50_zn_hook PF04423.14 CBZ29746.1 - 0.4 10.5 2.2 4.8 7.1 0.0 2.6 3 0 0 3 3 3 0 Rad50 zinc hook motif NinF PF05810.12 CBZ29746.1 - 1.4 8.9 9.8 1.9 8.4 0.2 3.3 3 0 0 3 3 3 0 NinF protein Sgf11 PF08209.11 CBZ29746.1 - 2.2 7.9 6.7 4.4 7.0 0.1 3.5 3 0 0 3 3 3 0 Sgf11 (transcriptional regulation protein) PLATZ PF04640.14 CBZ29746.1 - 2.2 8.9 8.5 16 6.2 0.7 3.3 4 0 0 4 4 4 0 PLATZ transcription factor RNase_PH_C PF03725.15 CBZ29747.1 - 2.1e-07 30.9 0.0 3.6e-07 30.1 0.0 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 RNase_PH PF01138.21 CBZ29747.1 - 4.7e-06 27.1 0.0 1.5e-05 25.5 0.0 1.8 2 0 0 2 2 2 1 3' exoribonuclease family, domain 1 RRM_1 PF00076.22 CBZ29748.1 - 9.1e-09 35.0 0.0 4.6e-06 26.4 0.0 2.9 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Rrn6 PF10214.9 CBZ29748.1 - 5 5.5 11.1 7.8 4.9 11.1 1.2 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor DUF3824 PF12868.7 CBZ29748.1 - 8.3 7.1 10.7 19 5.9 10.7 1.6 1 0 0 1 1 1 0 Domain of unknwon function (DUF3824) TPR_19 PF14559.6 CBZ29749.1 - 0.47 11.0 0.0 0.47 11.0 0.0 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat DEAD PF00270.29 CBZ29750.1 - 1.2e-17 64.3 0.0 2.8e-17 63.1 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CBZ29750.1 - 1.2e-05 25.6 0.0 4.3e-05 23.8 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 CBZ29750.1 - 0.0018 18.3 0.0 0.0031 17.6 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 CBZ29750.1 - 0.012 15.9 0.2 0.43 10.8 0.2 2.9 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 CBZ29750.1 - 0.015 15.7 0.0 0.58 10.6 0.0 3.0 3 1 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) NAD_binding_7 PF13241.6 CBZ29750.1 - 0.024 15.1 0.0 0.18 12.2 0.0 2.6 3 1 0 3 3 3 0 Putative NAD(P)-binding SAP130_C PF16014.5 CBZ29750.1 - 0.063 12.4 1.0 0.55 9.3 0.2 2.2 2 0 0 2 2 2 0 Histone deacetylase complex subunit SAP130 C-terminus PhoH PF02562.16 CBZ29750.1 - 0.066 12.7 0.0 0.12 11.8 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein Rho_N PF07498.12 CBZ29751.1 - 0.093 12.7 0.1 0.3 11.1 0.1 1.8 1 0 0 1 1 1 0 Rho termination factor, N-terminal domain Cytochrome_CBB3 PF13442.6 CBZ29752.1 - 0.16 12.3 0.5 6.3 7.2 0.1 3.2 2 1 0 2 2 2 0 Cytochrome C oxidase, cbb3-type, subunit III Robl_LC7 PF03259.17 CBZ29753.1 - 5e-08 32.6 0.1 4.6e-07 29.5 0.1 2.0 2 0 0 2 2 2 1 Roadblock/LC7 domain LAMTOR5 PF16672.5 CBZ29753.1 - 0.041 13.8 0.0 0.051 13.5 0.0 1.4 1 0 0 1 1 1 0 Ragulator complex protein LAMTOR5 Methyltr_RsmB-F PF01189.17 CBZ29755.1 - 0.00066 19.4 0.0 0.0014 18.3 0.0 1.4 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F Bee_toxin PF17454.2 CBZ29756.1 - 0.066 13.3 0.3 0.11 12.5 0.3 1.3 1 0 0 1 1 1 0 Honey bee toxin MAP65_ASE1 PF03999.12 CBZ29757.1 - 0.0069 15.1 0.7 0.0084 14.9 0.7 1.1 1 0 0 1 1 1 1 Microtubule associated protein (MAP65/ASE1 family) LPP PF04728.13 CBZ29757.1 - 0.035 14.5 0.5 0.035 14.5 0.5 2.5 3 0 0 3 3 3 0 Lipoprotein leucine-zipper InvH PF04741.12 CBZ29757.1 - 0.057 13.4 0.0 0.081 12.8 0.0 1.2 1 0 0 1 1 1 0 InvH outer membrane lipoprotein RYDR_ITPR PF01365.21 CBZ29757.1 - 0.066 12.6 3.5 0.13 11.6 3.5 1.4 1 1 0 1 1 1 0 RIH domain Cob_adeno_trans PF01923.18 CBZ29757.1 - 0.27 11.4 4.3 0.23 11.6 1.3 2.2 1 1 1 2 2 2 0 Cobalamin adenosyltransferase Prefoldin PF02996.17 CBZ29757.1 - 0.87 9.5 6.9 10 6.1 0.0 3.3 3 1 1 4 4 4 0 Prefoldin subunit DUF4140 PF13600.6 CBZ29757.1 - 2.5 8.6 12.2 10 6.7 0.8 3.1 2 1 1 3 3 3 0 N-terminal domain of unknown function (DUF4140) YabA PF06156.13 CBZ29757.1 - 6.2 7.5 7.8 6.1 7.5 4.1 2.5 2 1 0 2 2 2 0 Initiation control protein YabA PH PF00169.29 CBZ29759.1 - 0.0012 19.3 0.0 0.0037 17.8 0.0 1.8 1 1 0 1 1 1 1 PH domain ECH_2 PF16113.5 CBZ29762.1 - 8e-22 78.2 0.0 8.9e-22 78.0 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 CBZ29763.1 - 7e-104 347.9 0.0 8e-104 347.7 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_1 PF00378.20 CBZ29763.1 - 9.2e-26 90.7 0.0 6.2e-24 84.7 0.0 2.1 2 0 0 2 2 2 2 Enoyl-CoA hydratase/isomerase zinc_ribbon_2 PF13240.6 CBZ29764.1 - 0.032 13.9 1.2 0.068 12.9 1.2 1.6 1 0 0 1 1 1 0 zinc-ribbon domain DZR PF12773.7 CBZ29764.1 - 0.067 13.2 0.3 0.15 12.1 0.3 1.5 1 0 0 1 1 1 0 Double zinc ribbon DUF2614 PF11023.8 CBZ29766.1 - 0.089 12.9 0.1 0.12 12.5 0.1 1.3 1 0 0 1 1 1 0 Zinc-ribbon containing domain BT1 PF03092.16 CBZ29767.1 - 2.4e-25 88.8 22.6 9.6e-17 60.4 7.8 2.1 2 0 0 2 2 2 2 BT1 family TMEM18 PF14770.6 CBZ29768.1 - 5.3e-28 97.4 0.7 6.6e-28 97.1 0.7 1.1 1 0 0 1 1 1 1 Transmembrane protein 18 DUF2921 PF11145.8 CBZ29768.1 - 0.098 10.5 0.0 0.12 10.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2921) WASH-7_C PF14746.6 CBZ29768.1 - 0.13 11.9 0.0 0.28 10.9 0.0 1.6 2 0 0 2 2 2 0 WASH complex subunit 7, C-terminal TYW3 PF02676.14 CBZ29770.1 - 2.5e-50 170.8 0.0 2.9e-50 170.6 0.0 1.0 1 0 0 1 1 1 1 Methyltransferase TYW3 V-ATPase_G_2 PF16999.5 CBZ29772.1 - 1.6 9.2 8.0 0.42 11.1 3.1 2.0 1 1 1 2 2 2 0 Vacuolar (H+)-ATPase G subunit CKS PF01111.19 CBZ29774.1 - 7.7e-37 125.4 1.1 9.3e-37 125.1 1.1 1.1 1 0 0 1 1 1 1 Cyclin-dependent kinase regulatory subunit TPR_1 PF00515.28 CBZ29775.1 - 1e-06 28.3 0.9 0.071 13.0 0.1 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 CBZ29775.1 - 1.6e-05 24.6 7.4 0.06 13.5 0.1 4.0 4 1 0 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.6 CBZ29775.1 - 4.5e-05 23.7 3.0 0.0059 16.9 0.1 2.4 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.6 CBZ29775.1 - 0.01 16.0 0.1 1 9.8 0.0 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_10 PF13374.6 CBZ29775.1 - 0.16 11.9 4.9 4.8 7.2 0.0 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.6 CBZ29775.1 - 2.4 9.0 11.0 14 6.6 0.3 4.5 4 1 1 5 5 5 0 Tetratricopeptide repeat SHQ1 PF04925.15 CBZ29776.1 - 5.8e-35 120.4 0.1 1.3e-34 119.3 0.0 1.5 2 0 0 2 2 2 1 SHQ1 protein ANAPC4_WD40 PF12894.7 CBZ29777.1 - 0.00016 21.9 0.0 0.67 10.3 0.0 3.8 2 2 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 CBZ29777.1 - 0.00039 21.2 3.1 9.8 7.2 0.0 4.6 4 0 0 4 4 4 2 WD domain, G-beta repeat Cornichon PF03311.14 CBZ29778.1 - 1.1e-15 58.0 7.3 1.1e-15 58.0 7.3 1.6 1 1 1 2 2 2 1 Cornichon protein Pox_P21 PF05313.12 CBZ29778.1 - 0.014 15.0 0.2 0.014 15.0 0.2 2.1 3 0 0 3 3 3 0 Poxvirus P21 membrane protein DUF4212 PF13937.6 CBZ29778.1 - 0.05 14.0 3.1 0.05 14.0 3.1 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF4212) CytochromB561_N PF09786.9 CBZ29778.1 - 0.47 9.4 2.8 0.22 10.5 0.6 1.5 1 1 1 2 2 2 0 Cytochrome B561, N terminal Cornichon PF03311.14 CBZ29779.1 - 1.5e-24 86.6 3.0 1.5e-24 86.6 3.0 1.8 1 1 1 2 2 2 1 Cornichon protein Wtap PF17098.5 CBZ29780.1 - 0.002 18.0 9.7 0.0024 17.8 2.9 2.8 1 1 3 4 4 4 1 WTAP/Mum2p family CENP-K PF11802.8 CBZ29780.1 - 0.0048 16.5 0.8 0.0048 16.5 0.8 1.8 2 0 0 2 2 2 1 Centromere-associated protein K bZIP_1 PF00170.21 CBZ29780.1 - 0.059 13.5 3.1 0.16 12.1 0.7 2.6 2 0 0 2 2 2 0 bZIP transcription factor Nnf1 PF03980.14 CBZ29780.1 - 0.12 12.7 0.4 0.12 12.7 0.4 3.0 3 0 0 3 3 3 0 Nnf1 HAUS-augmin3 PF14932.6 CBZ29780.1 - 0.27 10.8 13.4 1.7 8.2 1.7 2.1 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 3 Dsh_C PF12316.8 CBZ29780.1 - 0.27 11.6 3.2 0.13 12.7 0.7 1.7 2 0 0 2 2 2 0 Segment polarity protein dishevelled (Dsh) C terminal Exonuc_VII_S PF02609.16 CBZ29780.1 - 0.72 10.0 4.3 0.76 9.9 1.0 2.6 3 0 0 3 3 3 0 Exonuclease VII small subunit DUF812 PF05667.11 CBZ29780.1 - 0.91 8.3 10.7 0.19 10.6 5.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF812) DUF1192 PF06698.11 CBZ29780.1 - 1.2 9.2 10.2 4 7.6 1.9 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF1192) Swi5 PF07061.11 CBZ29780.1 - 1.2 9.2 4.7 1.3 9.2 0.3 2.6 2 1 0 2 2 2 0 Swi5 DivIC PF04977.15 CBZ29780.1 - 2.3 8.1 5.8 3.8 7.4 2.8 2.5 2 1 0 2 2 2 0 Septum formation initiator NYD-SP28_assoc PF14775.6 CBZ29780.1 - 2.3 8.4 9.1 0.54 10.4 1.1 3.0 3 0 0 3 3 3 0 Sperm tail C-terminal domain Flg_hook PF02120.16 CBZ29780.1 - 2.8 7.9 7.3 0.36 10.7 2.1 2.2 3 0 0 3 3 3 0 Flagellar hook-length control protein FliK ABC_tran_CTD PF16326.5 CBZ29780.1 - 3.2 8.1 8.3 5.5 7.3 0.5 2.9 2 1 0 2 2 2 0 ABC transporter C-terminal domain Jnk-SapK_ap_N PF09744.9 CBZ29780.1 - 5.6 7.2 16.6 1.1 9.5 2.1 2.1 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 DUF737 PF05300.11 CBZ29781.1 - 0.063 13.6 1.3 0.094 13.1 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF737) AP1AR PF15745.5 CBZ29781.1 - 0.9 9.1 5.5 2.7 7.6 0.9 2.6 2 0 0 2 2 2 0 AP-1 complex-associated regulatory protein Myosin_head PF00063.21 CBZ29782.1 - 1.5e-176 588.6 0.5 2.2e-176 588.0 0.1 1.4 2 0 0 2 2 2 1 Myosin head (motor domain) UBA PF00627.31 CBZ29782.1 - 6e-08 32.4 1.1 0.0035 17.2 0.5 2.8 2 0 0 2 2 2 2 UBA/TS-N domain AAA_16 PF13191.6 CBZ29782.1 - 0.0033 17.8 1.7 0.58 10.5 0.0 3.3 3 0 0 3 3 3 1 AAA ATPase domain AAA_22 PF13401.6 CBZ29782.1 - 0.0057 16.9 0.0 0.041 14.2 0.0 2.5 2 0 0 2 2 2 1 AAA domain Myosin_N PF02736.19 CBZ29782.1 - 0.024 14.5 0.1 0.07 13.0 0.1 1.7 1 0 0 1 1 1 0 Myosin N-terminal SH3-like domain Mg_chelatase PF01078.21 CBZ29782.1 - 0.032 13.6 0.0 0.098 12.0 0.0 1.8 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI Glyoxalase_6 PF18029.1 CBZ29782.1 - 0.1 13.4 2.5 0.25 12.2 0.1 2.5 2 0 0 2 2 2 0 Glyoxalase-like domain DUF2972 PF11186.8 CBZ29782.1 - 0.14 12.1 0.6 1.2 9.0 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF2972) AAA_lid_6 PF17866.1 CBZ29782.1 - 0.37 11.0 0.0 0.37 11.0 0.0 3.4 3 0 0 3 3 2 0 AAA lid domain DUF3306 PF11748.8 CBZ29782.1 - 1.6 9.6 5.9 21 6.0 0.6 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3306) Pet100 PF09803.9 CBZ29782.1 - 5.9 7.5 7.3 0.41 11.2 0.1 2.7 3 0 0 3 3 2 0 Pet100 Peptidase_C54 PF03416.19 CBZ29784.1 - 7.1e-44 150.3 0.0 9.6e-44 149.9 0.0 1.1 1 0 0 1 1 1 1 Peptidase family C54 Ribosomal_L2_C PF03947.18 CBZ29785.1 - 6.8e-43 145.9 3.7 1.2e-42 145.1 2.1 1.9 2 0 0 2 2 2 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.23 CBZ29785.1 - 5.2e-13 48.7 0.0 1.5e-12 47.3 0.0 1.8 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain COPIIcoated_ERV PF07970.12 CBZ29786.1 - 9.2e-37 127.0 0.2 1.2e-36 126.7 0.2 1.1 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.6 CBZ29786.1 - 7.8e-24 83.8 0.2 1.4e-23 83.0 0.2 1.4 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) DUF5534 PF17686.1 CBZ29786.1 - 2.5 8.3 4.7 18 5.5 0.3 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5534) ERCC3_RAD25_C PF16203.5 CBZ29787.1 - 6.9e-70 235.1 0.1 4.2e-69 232.5 0.0 2.1 2 0 0 2 2 2 1 ERCC3/RAD25/XPB C-terminal helicase Helicase_C_3 PF13625.6 CBZ29787.1 - 8.7e-17 61.5 0.2 2.5e-16 60.0 0.2 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 CBZ29787.1 - 4.5e-12 46.3 0.0 7.9e-12 45.5 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 CBZ29787.1 - 3.8e-10 40.1 0.0 1e-09 38.7 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.23 CBZ29787.1 - 0.00041 19.2 0.0 0.0008 18.2 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain HECT PF00632.25 CBZ29788.1 - 5.6e-38 131.2 0.5 1.6e-37 129.7 0.5 1.7 1 1 0 1 1 1 1 HECT-domain (ubiquitin-transferase) SPRY PF00622.28 CBZ29788.1 - 2.6e-25 88.9 0.0 1.3e-06 28.5 0.1 4.6 4 0 0 4 4 4 4 SPRY domain ZZ PF00569.17 CBZ29788.1 - 0.0014 18.4 9.1 0.0033 17.2 9.1 1.7 1 0 0 1 1 1 1 Zinc finger, ZZ type zf-UBR PF02207.20 CBZ29788.1 - 1.5 9.0 15.1 0.0087 16.2 4.5 2.6 2 0 0 2 2 2 0 Putative zinc finger in N-recognin (UBR box) PIN_4 PF13638.6 CBZ29789.1 - 0.0019 18.5 0.0 0.0079 16.5 0.0 2.1 1 1 0 1 1 1 1 PIN domain cNMP_binding PF00027.29 CBZ29792.1 - 1e-20 73.6 0.1 1.4e-07 31.5 0.0 4.2 3 1 0 3 3 3 3 Cyclic nucleotide-binding domain GCM PF03615.15 CBZ29792.1 - 0.12 12.3 0.1 0.32 10.9 0.1 1.7 1 0 0 1 1 1 0 GCM motif protein Gar1 PF04410.14 CBZ29793.1 - 1.8e-22 79.8 0.0 2.6e-22 79.3 0.0 1.2 1 0 0 1 1 1 1 Gar1/Naf1 RNA binding region Glycos_transf_2 PF00535.26 CBZ29794.1 - 1.8e-07 31.1 0.0 3.5e-07 30.2 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 CBZ29794.1 - 0.00049 20.1 0.0 0.0015 18.5 0.0 1.7 2 0 0 2 2 2 1 Glycosyltransferase like family 2 LysM PF01476.20 CBZ29795.1 - 1e-09 38.3 0.0 0.00029 20.8 0.0 3.2 3 0 0 3 3 3 2 LysM domain HTH_23 PF13384.6 CBZ29795.1 - 0.0017 18.1 0.0 6.5 6.7 0.0 3.6 3 0 0 3 3 3 2 Homeodomain-like domain DUF3606 PF12244.8 CBZ29795.1 - 0.022 14.7 0.4 1 9.3 0.0 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3606) HTH_3 PF01381.22 CBZ29795.1 - 0.034 14.2 0.0 1.1 9.4 0.0 2.8 3 0 0 3 3 3 0 Helix-turn-helix Fringe PF02434.16 CBZ29795.1 - 0.049 13.1 0.1 0.09 12.2 0.1 1.4 1 0 0 1 1 1 0 Fringe-like Death PF00531.22 CBZ29795.1 - 0.071 13.3 0.0 6.7 7.0 0.0 3.2 3 0 0 3 3 3 0 Death domain HTH_AsnC-type PF13404.6 CBZ29795.1 - 0.087 12.7 4.0 4.4 7.2 0.0 3.8 4 0 0 4 4 4 0 AsnC-type helix-turn-helix domain Herpes_UL52 PF03121.15 CBZ29797.1 - 1.8e-11 43.8 0.2 6.6e-11 42.0 0.2 2.0 1 0 0 1 1 1 1 Herpesviridae UL52/UL70 DNA primase Adeno_PV PF03910.13 CBZ29799.1 - 0.016 14.0 0.0 0.019 13.7 0.0 1.1 1 0 0 1 1 1 0 Adenovirus minor core protein PV FOP_dimer PF09398.10 CBZ29799.1 - 0.021 15.0 0.0 0.038 14.3 0.0 1.3 1 0 0 1 1 1 0 FOP N terminal dimerisation domain Med3 PF11593.8 CBZ29799.1 - 1.4 8.1 5.0 1.8 7.6 5.0 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal WD40 PF00400.32 CBZ29800.1 - 4.2e-25 87.5 13.5 9.4e-05 23.1 0.4 7.5 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBZ29800.1 - 9.1e-15 54.7 1.3 0.0071 16.6 0.1 5.5 1 1 3 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain PQQ_2 PF13360.6 CBZ29800.1 - 5.7e-05 22.8 0.3 0.00041 20.0 0.0 2.1 1 1 1 2 2 2 1 PQQ-like domain WDCP PF15390.6 CBZ29800.1 - 0.016 13.7 0.3 0.023 13.1 0.3 1.2 1 0 0 1 1 1 0 WD repeat and coiled-coil-containing protein family Frtz PF11768.8 CBZ29800.1 - 0.019 13.3 0.0 0.24 9.7 0.0 2.3 1 1 2 3 3 3 0 WD repeat-containing and planar cell polarity effector protein Fritz Ge1_WD40 PF16529.5 CBZ29800.1 - 0.025 13.5 0.9 4.9 6.0 0.0 3.2 2 1 2 4 4 4 0 WD40 region of Ge1, enhancer of mRNA-decapping protein PQQ PF01011.21 CBZ29800.1 - 0.042 13.8 0.0 8.1 6.6 0.0 3.2 3 0 0 3 3 3 0 PQQ enzyme repeat PQQ_3 PF13570.6 CBZ29800.1 - 0.2 12.2 1.3 12 6.5 0.1 3.4 3 1 0 3 3 3 0 PQQ-like domain HEAT PF02985.22 CBZ29801.1 - 2.8e-06 27.1 0.6 0.025 14.8 0.0 4.0 4 0 0 4 4 4 2 HEAT repeat UVR PF02151.19 CBZ29801.1 - 3.5e-06 26.6 4.9 0.004 16.9 0.2 2.6 2 0 0 2 2 2 2 UvrB/uvrC motif HEAT_2 PF13646.6 CBZ29801.1 - 0.009 16.4 0.9 1.8 9.0 0.0 3.3 3 1 1 4 4 4 1 HEAT repeats HEAT_EZ PF13513.6 CBZ29801.1 - 0.05 14.1 1.5 0.34 11.5 0.0 3.0 3 0 0 3 3 3 0 HEAT-like repeat Cnd3 PF12719.7 CBZ29801.1 - 0.079 12.1 0.0 0.19 10.9 0.0 1.6 1 0 0 1 1 1 0 Nuclear condensing complex subunits, C-term domain RecX PF02631.16 CBZ29802.1 - 0.03 14.8 1.7 0.054 14.0 1.7 1.3 1 0 0 1 1 1 0 RecX family Zip PF02535.22 CBZ29804.1 - 9.7e-13 48.0 15.9 4.2e-07 29.5 1.1 3.1 2 1 1 3 3 3 3 ZIP Zinc transporter CEP19 PF14933.6 CBZ29807.1 - 4e-52 176.9 0.0 6.9e-52 176.1 0.0 1.4 1 0 0 1 1 1 1 CEP19-like protein Nop PF01798.18 CBZ29808.1 - 1.3e-45 155.7 0.0 1.5e-45 155.5 0.0 1.1 1 0 0 1 1 1 1 snoRNA binding domain, fibrillarin DUF4027 PF13219.6 CBZ29808.1 - 8.1 6.4 6.3 1.6 8.7 0.1 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF4027) Ank_2 PF12796.7 CBZ29809.1 - 1.3e-15 57.7 1.5 9.3e-08 32.6 0.3 2.2 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 CBZ29809.1 - 2e-06 27.7 0.1 0.0052 17.2 0.1 3.3 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.6 CBZ29809.1 - 1.9e-05 25.1 0.7 0.00037 21.0 0.1 3.1 3 1 1 4 4 4 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 CBZ29809.1 - 0.00019 21.6 0.9 0.002 18.4 0.4 2.6 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 CBZ29809.1 - 0.0034 17.8 0.5 0.0034 17.8 0.5 3.4 4 0 0 4 4 4 1 Ankyrin repeat Iwr1 PF08574.10 CBZ29810.1 - 0.003 18.5 7.6 0.003 18.5 7.6 2.1 2 1 0 2 2 2 1 Transcription factor Iwr1 Tetraspanin PF00335.20 CBZ29812.1 - 1.6e-09 37.8 13.1 2.4e-09 37.3 13.1 1.2 1 0 0 1 1 1 1 Tetraspanin family DUF1772 PF08592.11 CBZ29812.1 - 0.051 13.9 5.8 0.56 10.5 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF1772) CTF_NFI PF00859.18 CBZ29814.1 - 0.018 15.0 1.5 0.041 13.8 0.3 2.0 2 0 0 2 2 2 0 CTF/NF-I family transcription modulation region BCAS3 PF12490.8 CBZ29814.1 - 0.056 13.0 0.0 0.092 12.3 0.0 1.4 1 0 0 1 1 1 0 Breast carcinoma amplified sequence 3 Peptidase_M14 PF00246.24 CBZ29815.1 - 4.5e-12 46.4 0.0 9.2e-12 45.3 0.0 1.4 1 0 0 1 1 1 1 Zinc carboxypeptidase Pepdidase_M14_N PF18027.1 CBZ29815.1 - 8.2e-09 35.8 0.2 3.4e-08 33.8 0.1 2.2 2 0 0 2 2 2 1 Cytosolic carboxypeptidase N-terminal domain PRIMA1 PF16101.5 CBZ29815.1 - 3.5 7.7 8.6 1.4 9.0 5.6 1.9 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 DHHC PF01529.20 CBZ29818.1 - 3.8e-46 156.5 5.1 3.8e-46 156.5 5.1 2.0 2 1 0 2 2 2 1 DHHC palmitoyltransferase A_deamin PF02137.18 CBZ29819.1 - 4.4e-18 65.8 0.0 1e-17 64.6 0.0 1.8 1 1 0 1 1 1 1 Adenosine-deaminase (editase) domain DUF3761 PF12587.8 CBZ29819.1 - 0.62 10.5 3.9 0.66 10.5 0.1 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF3761) GST_C_5 PF16865.5 CBZ29820.1 - 2.3e-96 317.6 0.8 5.4e-51 171.7 0.1 2.2 2 0 0 2 2 2 2 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 CBZ29820.1 - 2.6e-24 85.4 0.0 3.5e-16 59.4 0.1 2.5 2 0 0 2 2 2 2 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 CBZ29820.1 - 1.5e-19 70.0 0.2 8e-12 45.3 0.1 2.3 2 0 0 2 2 2 2 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 CBZ29820.1 - 4.7e-17 62.1 0.3 8.7e-09 35.6 0.0 3.2 4 0 0 4 4 4 2 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 CBZ29820.1 - 3.4e-15 55.8 1.8 4.4e-07 29.8 0.2 2.5 2 0 0 2 2 2 2 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 CBZ29820.1 - 0.00017 21.8 0.0 0.049 13.9 0.0 2.6 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 CBZ29820.1 - 0.00019 21.6 0.0 0.017 15.3 0.0 2.9 3 0 0 3 3 3 1 Glutathione S-transferase, C-terminal domain Glutaredoxin PF00462.24 CBZ29820.1 - 0.042 14.1 0.6 0.61 10.3 0.1 2.4 2 0 0 2 2 2 0 Glutaredoxin RRM_1 PF00076.22 CBZ29822.1 - 3.1e-09 36.5 0.0 4.6e-09 36.0 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 CBZ29822.1 - 0.0025 17.8 0.0 0.0042 17.1 0.0 1.4 1 1 0 1 1 1 1 RNA binding motif RRM_occluded PF16842.5 CBZ29822.1 - 0.015 15.1 0.0 0.024 14.5 0.0 1.2 1 0 0 1 1 1 0 Occluded RNA-recognition motif Mpv17_PMP22 PF04117.12 CBZ29823.1 - 1e-08 35.3 1.3 1.9e-08 34.4 1.3 1.4 1 0 0 1 1 1 1 Mpv17 / PMP22 family WD40 PF00400.32 CBZ29824.1 - 1.2e-18 67.0 10.9 0.0012 19.7 0.0 7.2 6 1 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBZ29824.1 - 3.5e-07 30.4 0.0 2.4 8.5 0.0 4.5 3 2 2 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain CSTF1_dimer PF16699.5 CBZ29824.1 - 0.0012 18.6 0.0 0.0031 17.2 0.0 1.7 1 0 0 1 1 1 1 Cleavage stimulation factor subunit 1, dimerisation domain Ge1_WD40 PF16529.5 CBZ29824.1 - 0.0099 14.9 0.0 8.2 5.3 0.0 3.3 3 1 0 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 CBZ29824.1 - 0.046 13.7 0.2 67 3.6 0.0 3.8 3 1 1 4 4 4 0 WD40-like Beta Propeller Repeat LAL_C2 PF18603.1 CBZ29824.1 - 0.83 9.9 3.8 0.38 10.9 0.3 2.3 3 0 0 3 3 3 0 L-amino acid ligase C-terminal domain 2 Sugar_tr PF00083.24 CBZ29825.1 - 2.4e-138 461.8 27.6 2.9e-138 461.5 27.6 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CBZ29825.1 - 2e-12 46.7 26.2 2e-12 46.7 26.2 2.2 1 1 1 2 2 2 1 Major Facilitator Superfamily YlmH_RBD PF17774.1 CBZ29825.1 - 0.12 12.7 0.0 0.24 11.7 0.0 1.4 1 0 0 1 1 1 0 Putative RNA-binding domain in YlmH Autophagy_N PF03986.13 CBZ29826.1 - 1.9e-25 89.4 0.2 3e-25 88.8 0.2 1.3 1 0 0 1 1 1 1 Autophagocytosis associated protein (Atg3), N-terminal domain Autophagy_act_C PF03987.15 CBZ29826.1 - 1.5e-19 70.3 1.6 3.1e-19 69.3 1.6 1.6 1 0 0 1 1 1 1 Autophagocytosis associated protein, active-site domain Autophagy_C PF10381.9 CBZ29826.1 - 3.3e-10 39.3 0.6 7.7e-10 38.1 0.6 1.6 1 0 0 1 1 1 1 Autophagocytosis associated protein C-terminal Glycos_transf_2 PF00535.26 CBZ29827.1 - 0.028 14.2 0.0 0.046 13.5 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase family 2 ABC_tran PF00005.27 CBZ29828.1 - 1.6e-44 151.7 0.1 1.3e-20 74.3 0.0 3.3 3 0 0 3 3 2 2 ABC transporter AAA_21 PF13304.6 CBZ29828.1 - 1.8e-17 64.1 1.3 0.00042 20.2 0.0 4.3 3 1 1 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 CBZ29828.1 - 2.3e-10 40.3 6.0 0.00022 20.7 0.0 5.1 4 2 1 5 5 4 2 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 CBZ29828.1 - 6.5e-08 32.7 0.3 0.0081 16.1 0.0 2.9 2 0 0 2 2 2 2 RsgA GTPase AAA_29 PF13555.6 CBZ29828.1 - 1e-07 31.6 0.3 0.014 15.1 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.6 CBZ29828.1 - 0.00024 21.4 0.0 0.42 10.9 0.0 3.0 2 0 0 2 2 2 2 AAA domain AAA_15 PF13175.6 CBZ29828.1 - 0.00056 19.7 6.2 0.38 10.4 0.0 4.6 3 1 1 4 4 4 2 AAA ATPase domain AAA_16 PF13191.6 CBZ29828.1 - 0.00062 20.2 1.6 1.3 9.4 0.0 3.2 3 0 0 3 3 3 2 AAA ATPase domain AAA_28 PF13521.6 CBZ29828.1 - 0.00063 20.0 3.4 0.072 13.3 0.1 3.2 3 0 0 3 3 3 1 AAA domain MMR_HSR1 PF01926.23 CBZ29828.1 - 0.00071 19.6 0.0 0.24 11.5 0.0 3.0 2 0 0 2 2 2 1 50S ribosome-binding GTPase RNA_helicase PF00910.22 CBZ29828.1 - 0.0012 19.2 0.0 0.96 9.9 0.0 2.6 2 0 0 2 2 2 1 RNA helicase AAA PF00004.29 CBZ29828.1 - 0.0012 19.3 0.2 1.4 9.4 0.0 3.5 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_23 PF13476.6 CBZ29828.1 - 0.0024 18.4 0.3 0.09 13.3 0.0 4.9 6 0 0 6 6 4 2 AAA domain ABC_tran_Xtn PF12848.7 CBZ29828.1 - 0.003 17.6 3.4 0.003 17.6 3.4 4.1 4 1 0 4 4 2 1 ABC transporter AAA_5 PF07728.14 CBZ29828.1 - 0.0031 17.5 0.1 1.7 8.7 0.1 2.8 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_33 PF13671.6 CBZ29828.1 - 0.0035 17.5 0.6 0.99 9.6 0.0 3.3 4 0 0 4 4 3 1 AAA domain AAA_14 PF13173.6 CBZ29828.1 - 0.0045 17.0 0.0 1.7 8.7 0.0 3.1 2 0 0 2 2 2 1 AAA domain AAA_24 PF13479.6 CBZ29828.1 - 0.0095 15.7 3.5 0.76 9.5 0.0 3.8 3 1 1 4 4 4 1 AAA domain SbcCD_C PF13558.6 CBZ29828.1 - 0.018 15.3 0.5 0.77 10.0 0.1 3.5 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit Rad17 PF03215.15 CBZ29828.1 - 0.031 14.2 0.1 12 5.8 0.0 2.6 3 0 0 3 3 2 0 Rad17 P-loop domain NTPase_1 PF03266.15 CBZ29828.1 - 0.056 13.3 0.0 1.8 8.4 0.0 2.7 2 0 0 2 2 2 0 NTPase NACHT PF05729.12 CBZ29828.1 - 0.13 12.1 0.1 11 5.9 0.1 2.5 2 0 0 2 2 2 0 NACHT domain AAA_18 PF13238.6 CBZ29828.1 - 2.3 8.8 0.0 2.3 8.8 0.0 3.7 5 1 1 6 6 3 0 AAA domain HSP90 PF00183.18 CBZ29829.1 - 4.5e-228 758.3 29.3 5.9e-228 758.0 29.3 1.0 1 0 0 1 1 1 1 Hsp90 protein HATPase_c PF02518.26 CBZ29829.1 - 1.8e-16 60.6 0.0 3.8e-16 59.6 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 CBZ29829.1 - 4.5e-11 42.7 0.1 1.3e-10 41.2 0.1 1.9 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Ribosomal_S20p PF01649.18 CBZ29829.1 - 0.0064 17.1 0.5 0.0064 17.1 0.5 3.9 5 0 0 5 5 5 1 Ribosomal protein S20 SecB PF02556.14 CBZ29829.1 - 0.071 13.0 0.0 0.2 11.5 0.0 1.7 1 0 0 1 1 1 0 Preprotein translocase subunit SecB HSP90 PF00183.18 CBZ29830.1 - 4.5e-228 758.3 29.3 5.9e-228 758.0 29.3 1.0 1 0 0 1 1 1 1 Hsp90 protein HATPase_c PF02518.26 CBZ29830.1 - 1.8e-16 60.6 0.0 3.8e-16 59.6 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 CBZ29830.1 - 4.5e-11 42.7 0.1 1.3e-10 41.2 0.1 1.9 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Ribosomal_S20p PF01649.18 CBZ29830.1 - 0.0064 17.1 0.5 0.0064 17.1 0.5 3.9 5 0 0 5 5 5 1 Ribosomal protein S20 SecB PF02556.14 CBZ29830.1 - 0.071 13.0 0.0 0.2 11.5 0.0 1.7 1 0 0 1 1 1 0 Preprotein translocase subunit SecB HSP90 PF00183.18 CBZ29831.1 - 4.5e-228 758.3 29.3 5.9e-228 758.0 29.3 1.0 1 0 0 1 1 1 1 Hsp90 protein HATPase_c PF02518.26 CBZ29831.1 - 1.8e-16 60.6 0.0 3.8e-16 59.6 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 CBZ29831.1 - 4.5e-11 42.7 0.1 1.3e-10 41.2 0.1 1.9 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Ribosomal_S20p PF01649.18 CBZ29831.1 - 0.0064 17.1 0.5 0.0064 17.1 0.5 3.9 5 0 0 5 5 5 1 Ribosomal protein S20 SecB PF02556.14 CBZ29831.1 - 0.071 13.0 0.0 0.2 11.5 0.0 1.7 1 0 0 1 1 1 0 Preprotein translocase subunit SecB WD40 PF00400.32 CBZ29832.1 - 7.4e-11 42.4 1.0 0.0001 23.0 0.0 5.2 4 0 0 4 4 4 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBZ29832.1 - 0.00013 22.2 0.0 0.74 10.1 0.0 3.8 2 1 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain DUF4586 PF15239.6 CBZ29834.1 - 0.081 13.1 0.5 0.36 11.0 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4586) Abhydrolase_1 PF00561.20 CBZ29835.1 - 1e-11 45.0 0.7 1.1e-08 35.1 0.8 2.3 2 0 0 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 CBZ29835.1 - 4.8e-11 42.4 1.5 1.5e-06 27.7 1.2 2.4 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 CBZ29835.1 - 0.00013 22.6 3.9 0.00039 21.1 3.9 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 CBZ29835.1 - 0.0061 16.1 0.0 0.05 13.1 0.0 2.1 1 1 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_2 PF02230.16 CBZ29835.1 - 0.011 15.6 0.3 0.46 10.3 0.3 2.3 1 1 0 1 1 1 0 Phospholipase/Carboxylesterase FSH1 PF03959.13 CBZ29835.1 - 0.016 14.9 0.0 0.028 14.1 0.0 1.3 1 0 0 1 1 1 0 Serine hydrolase (FSH1) DLH PF01738.18 CBZ29835.1 - 0.042 13.4 0.0 0.15 11.6 0.0 1.9 1 1 0 1 1 1 0 Dienelactone hydrolase family Abhydrolase_3 PF07859.13 CBZ29835.1 - 0.049 13.5 0.2 0.32 10.8 0.2 2.1 2 0 0 2 2 2 0 alpha/beta hydrolase fold MutS_V PF00488.21 CBZ29836.1 - 9.9e-74 247.5 0.0 1.8e-73 246.6 0.0 1.4 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 CBZ29836.1 - 5.1e-27 95.3 0.5 5.1e-27 95.3 0.5 2.1 2 0 0 2 2 2 1 MutS domain III MutS_IV PF05190.18 CBZ29836.1 - 6.8e-17 61.6 1.4 1.4e-16 60.6 1.4 1.6 1 0 0 1 1 1 1 MutS family domain IV Lipoprotein_7 PF01540.16 CBZ29836.1 - 0.028 13.7 0.8 2.8 7.2 0.0 2.4 2 0 0 2 2 2 0 Adhesin lipoprotein MutS_II PF05188.17 CBZ29836.1 - 0.031 14.5 1.4 0.099 12.9 0.1 2.4 2 0 0 2 2 2 0 MutS domain II AAA_29 PF13555.6 CBZ29836.1 - 0.039 13.7 0.0 0.64 9.8 0.0 2.4 2 0 0 2 2 2 0 P-loop containing region of AAA domain R2K_3 PF14243.6 CBZ29836.1 - 0.063 13.3 0.1 0.26 11.3 0.0 2.0 3 0 0 3 3 3 0 ATP-grasp domain, R2K clade family 3 MnmE_helical PF12631.7 CBZ29836.1 - 0.079 13.1 2.4 0.15 12.2 0.4 2.2 2 0 0 2 2 2 0 MnmE helical domain Tup_N PF08581.10 CBZ29836.1 - 3.8 7.9 5.2 25 5.2 0.0 3.4 4 0 0 4 4 4 0 Tup N-terminal ECH_2 PF16113.5 CBZ29838.1 - 0.072 12.6 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 Enoyl-CoA hydratase/isomerase FAD_binding_7 PF03441.14 CBZ29842.1 - 2.2e-68 229.7 1.8 4e-68 228.9 1.8 1.4 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.18 CBZ29842.1 - 9e-32 110.3 0.0 2.2e-31 109.1 0.0 1.6 2 0 0 2 2 2 1 DNA photolyase CALM_bind PF16025.5 CBZ29843.1 - 4.8 7.7 7.2 0.62 10.6 2.0 2.2 2 0 0 2 2 2 0 Calcium-dependent calmodulin binding HTH_Tnp_ISL3 PF13542.6 CBZ29844.1 - 0.0085 15.5 0.3 0.0085 15.5 0.3 3.0 3 0 0 3 3 3 1 Helix-turn-helix domain of transposase family ISL3 SET PF00856.28 CBZ29846.1 - 3.6e-08 34.0 0.0 6.9e-08 33.1 0.0 1.6 1 1 0 1 1 1 1 SET domain ADH_N PF08240.12 CBZ29847.1 - 6.3e-24 84.0 0.6 1.6e-23 82.6 0.1 1.9 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 CBZ29847.1 - 1.7e-17 63.6 0.1 3.3e-17 62.7 0.0 1.5 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 CBZ29847.1 - 9.4e-05 23.5 0.0 0.00019 22.5 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 CBZ29847.1 - 0.00029 20.4 0.4 0.00087 18.8 0.3 1.8 2 0 0 2 2 2 1 Glucose dehydrogenase C-terminus LRR_4 PF12799.7 CBZ29848.1 - 1.1e-21 76.6 0.0 0.0017 18.7 0.0 8.8 8 2 1 10 10 10 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CBZ29848.1 - 2.4e-14 52.8 1.0 0.0052 16.5 0.0 7.0 6 2 2 8 8 8 5 Leucine rich repeat LRR_6 PF13516.6 CBZ29848.1 - 0.0036 17.2 4.8 0.28 11.3 0.2 5.4 5 0 0 5 5 5 1 Leucine Rich repeat LRR_1 PF00560.33 CBZ29848.1 - 0.12 13.0 7.2 8.3 7.4 0.4 6.6 6 1 0 6 6 6 0 Leucine Rich Repeat NifU PF01106.17 CBZ29850.1 - 3.7e-19 68.6 0.0 1.1e-18 67.2 0.0 1.8 1 0 0 1 1 1 1 NifU-like domain Nfu_N PF08712.11 CBZ29850.1 - 1.2e-12 47.7 0.1 4.1e-10 39.6 0.0 2.5 2 0 0 2 2 2 2 Scaffold protein Nfu/NifU N terminal DUF2277 PF10041.9 CBZ29850.1 - 4.3 7.8 8.3 39 4.7 1.2 3.8 4 0 0 4 4 4 0 Uncharacterized conserved protein (DUF2277) RtcB PF01139.17 CBZ29852.1 - 9.5e-95 318.2 0.0 1.3e-94 317.7 0.0 1.2 1 0 0 1 1 1 1 tRNA-splicing ligase RtcB Polysacc_deac_2 PF04748.13 CBZ29852.1 - 0.15 11.2 0.0 1.8 7.7 0.0 2.0 2 0 0 2 2 2 0 Divergent polysaccharide deacetylase FYVE PF01363.21 CBZ29853.1 - 0.033 14.3 14.2 0.13 12.4 14.2 1.8 1 1 0 1 1 1 0 FYVE zinc finger Nkap_C PF06047.11 CBZ29855.1 - 9.3e-15 54.6 2.8 1e-14 54.5 0.9 1.9 2 0 0 2 2 2 1 NF-kappa-B-activating protein C-terminal domain BRE1 PF08647.11 CBZ29857.1 - 5.5e-12 45.6 11.6 5.5e-12 45.6 11.6 10.9 4 2 8 12 12 12 3 BRE1 E3 ubiquitin ligase DUF4094 PF13334.6 CBZ29857.1 - 0.0095 16.3 3.8 0.0095 16.3 3.8 8.9 3 2 6 9 9 9 1 Domain of unknown function (DUF4094) DUF724 PF05266.14 CBZ29857.1 - 0.19 11.5 122.7 0.022 14.6 1.9 9.0 3 2 7 10 10 10 0 Protein of unknown function (DUF724) AAA_13 PF13166.6 CBZ29857.1 - 0.3 9.7 109.3 0.015 13.9 10.7 6.5 1 1 4 6 6 6 0 AAA domain rve_3 PF13683.6 CBZ29857.1 - 2.6 7.9 4.4 8.9 6.2 0.1 3.9 3 0 0 3 3 3 0 Integrase core domain IGR PF09597.10 CBZ29858.1 - 1.9e-05 24.7 0.0 3.3e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 IGR protein motif TPR_7 PF13176.6 CBZ29859.1 - 0.00012 21.8 0.3 8.1 6.7 0.0 4.9 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_21 PF09976.9 CBZ29859.1 - 0.002 17.9 1.3 0.26 11.0 0.2 2.8 3 0 0 3 3 3 2 Tetratricopeptide repeat-like domain ANAPC3 PF12895.7 CBZ29859.1 - 0.0056 16.9 0.2 9.4 6.6 0.0 4.1 4 0 0 4 4 4 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_2 PF07719.17 CBZ29859.1 - 0.11 12.6 0.0 31 5.0 0.0 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat IFT57 PF10498.9 CBZ29861.1 - 3.7e-64 217.0 6.7 4.3e-64 216.8 6.7 1.0 1 0 0 1 1 1 1 Intra-flagellar transport protein 57 TPR_MLP1_2 PF07926.12 CBZ29861.1 - 0.0002 21.4 8.9 0.099 12.7 0.5 2.5 2 0 0 2 2 2 2 TPR/MLP1/MLP2-like protein HBM PF16591.5 CBZ29861.1 - 0.00027 20.4 7.8 0.00045 19.7 7.8 1.3 1 0 0 1 1 1 1 Helical bimodular sensor domain mRNA_stabil PF13929.6 CBZ29861.1 - 0.0023 16.9 1.0 0.007 15.4 0.0 1.8 1 1 1 2 2 2 1 mRNA stabilisation KxDL PF10241.9 CBZ29861.1 - 0.0024 18.1 3.6 1 9.7 0.6 2.6 2 0 0 2 2 2 2 Uncharacterized conserved protein CREPT PF16566.5 CBZ29861.1 - 0.0024 18.0 5.4 0.0042 17.3 5.4 1.4 1 0 0 1 1 1 1 Cell-cycle alteration and expression-elevated protein in tumour CHDCT2 PF08074.11 CBZ29861.1 - 0.0035 17.5 4.8 0.2 11.8 2.3 2.2 1 1 1 2 2 2 1 CHDCT2 (NUC038) domain Apolipoprotein PF01442.18 CBZ29861.1 - 0.0037 17.2 12.3 0.012 15.5 12.2 1.9 1 1 0 1 1 1 1 Apolipoprotein A1/A4/E domain Peptidase_M75 PF09375.10 CBZ29861.1 - 0.008 15.7 1.6 0.014 14.9 1.6 1.3 1 0 0 1 1 1 1 Imelysin AAA_13 PF13166.6 CBZ29861.1 - 0.01 14.5 3.8 0.013 14.2 3.8 1.2 1 0 0 1 1 1 0 AAA domain Spc7 PF08317.11 CBZ29861.1 - 0.018 14.0 12.7 0.043 12.7 11.1 1.9 1 1 1 2 2 2 0 Spc7 kinetochore protein UvrD_C PF13361.6 CBZ29861.1 - 0.024 14.0 0.6 0.029 13.7 0.6 1.1 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain FRB_dom PF08771.11 CBZ29861.1 - 0.038 14.4 1.5 0.18 12.2 0.9 2.0 1 1 1 2 2 2 0 FKBP12-rapamycin binding domain Laminin_II PF06009.12 CBZ29861.1 - 0.071 13.1 10.1 0.85 9.6 0.4 2.4 1 1 1 2 2 2 0 Laminin Domain II Phage_GPO PF05929.11 CBZ29861.1 - 0.08 12.6 4.7 0.12 12.0 4.7 1.4 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase SAT PF16073.5 CBZ29861.1 - 0.081 12.6 0.2 0.13 12.0 0.2 1.3 1 0 0 1 1 1 0 Starter unit:ACP transacylase in aflatoxin biosynthesis DUF745 PF05335.13 CBZ29861.1 - 0.082 12.6 9.8 1.3 8.7 8.0 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF745) Exonuc_VII_L PF02601.15 CBZ29861.1 - 0.11 12.0 9.8 0.2 11.2 9.8 1.5 1 1 0 1 1 1 0 Exonuclease VII, large subunit DUF1664 PF07889.12 CBZ29861.1 - 0.14 12.2 10.1 0.47 10.5 3.4 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Sec8_exocyst PF04048.14 CBZ29861.1 - 0.16 11.9 6.3 0.19 11.6 3.7 2.1 1 1 1 2 2 2 0 Sec8 exocyst complex component specific domain Fzo_mitofusin PF04799.13 CBZ29861.1 - 0.4 10.2 9.1 0.37 10.3 7.5 1.7 1 1 0 1 1 1 0 fzo-like conserved region Atg14 PF10186.9 CBZ29861.1 - 0.52 9.4 11.3 0.86 8.6 10.1 1.7 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF5063 PF16702.5 CBZ29861.1 - 0.53 10.7 4.2 15 5.9 4.2 2.3 1 1 0 1 1 1 0 Domain of unknown function (DUF5063) FUSC PF04632.12 CBZ29861.1 - 0.54 8.7 1.9 0.76 8.2 1.9 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family UPF0242 PF06785.11 CBZ29861.1 - 0.54 10.3 9.3 0.84 9.7 9.3 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus PRKG1_interact PF15898.5 CBZ29861.1 - 0.69 10.8 9.2 0.37 11.7 6.6 2.0 2 0 0 2 2 1 0 cGMP-dependent protein kinase interacting domain Prominin PF05478.11 CBZ29861.1 - 0.69 7.8 6.2 0.88 7.4 6.2 1.1 1 0 0 1 1 1 0 Prominin DUF2203 PF09969.9 CBZ29861.1 - 1.8 9.3 6.8 12 6.6 6.5 2.4 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) Ead_Ea22 PF13935.6 CBZ29861.1 - 2.6 8.7 8.2 9.3 6.9 4.0 2.5 1 1 1 2 2 2 0 Ead/Ea22-like protein DUF883 PF05957.13 CBZ29861.1 - 3.3 8.4 8.3 4.4 8.0 0.9 2.5 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) DUF948 PF06103.11 CBZ29861.1 - 3.9 7.8 6.2 55 4.1 6.0 2.6 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF948) XhlA PF10779.9 CBZ29861.1 - 6.1 7.1 8.2 12 6.2 0.6 3.0 2 1 0 2 2 2 0 Haemolysin XhlA YjbH PF06082.11 CBZ29861.1 - 7.8 5.2 8.7 21 3.7 8.7 1.7 1 1 0 1 1 1 0 Exopolysaccharide biosynthesis protein YbjH EF-hand_7 PF13499.6 CBZ29863.1 - 2.1e-05 24.9 0.1 4.2e-05 23.9 0.1 1.5 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.6 CBZ29863.1 - 0.0004 20.1 0.0 0.0012 18.6 0.0 1.8 1 0 0 1 1 1 1 EF-hand domain EF-hand_1 PF00036.32 CBZ29863.1 - 0.00065 19.1 0.1 0.0022 17.4 0.0 2.0 1 1 0 1 1 1 1 EF hand EF-hand_5 PF13202.6 CBZ29863.1 - 0.063 12.8 0.0 0.16 11.5 0.0 1.7 1 0 0 1 1 1 0 EF hand Aminotran_1_2 PF00155.21 CBZ29864.1 - 0.12 11.6 1.7 0.26 10.4 1.7 1.6 1 0 0 1 1 1 0 Aminotransferase class I and II EF1_GNE PF00736.19 CBZ29864.1 - 1.4 9.2 3.9 1.1e+02 3.1 0.9 4.0 3 0 0 3 3 3 0 EF-1 guanine nucleotide exchange domain WD40 PF00400.32 CBZ29866.1 - 0.0074 17.1 0.9 37 5.4 0.1 4.6 4 0 0 4 4 4 1 WD domain, G-beta repeat T2SSC PF11356.8 CBZ29866.1 - 0.77 9.7 2.9 2.2 8.2 2.9 1.7 1 0 0 1 1 1 0 Type II secretion system protein C Miga PF10265.9 CBZ29866.1 - 1.4 7.8 7.5 0.75 8.7 5.5 1.4 1 1 0 1 1 1 0 Mitoguardin ERG4_ERG24 PF01222.17 CBZ29867.1 - 4e-103 345.5 25.9 4.9e-103 345.2 25.9 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family Corona_nucleoca PF00937.18 CBZ29867.1 - 1.2 8.1 6.7 1.9 7.4 6.7 1.2 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein DUF4131 PF13567.6 CBZ29867.1 - 3.2 7.4 5.5 1.9 8.1 0.3 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) TPR_2 PF07719.17 CBZ29869.1 - 0.02 14.9 9.3 0.15 12.3 0.0 3.5 4 0 0 4 4 4 0 Tetratricopeptide repeat ANAPC3 PF12895.7 CBZ29869.1 - 0.049 13.9 4.1 0.099 12.9 4.1 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.6 CBZ29869.1 - 0.061 13.8 1.4 0.1 13.1 0.4 1.9 2 0 0 2 2 2 0 Tetratricopeptide repeat Ub-RnfH PF03658.14 CBZ29869.1 - 0.079 13.4 0.0 0.22 11.9 0.0 1.7 1 0 0 1 1 1 0 RnfH family Ubiquitin TPR_1 PF00515.28 CBZ29869.1 - 0.089 12.6 8.2 0.83 9.6 0.0 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat PTR2 PF00854.21 CBZ29870.1 - 2.7e-35 121.9 0.7 3.9e-33 114.9 0.0 2.9 2 1 0 2 2 2 2 POT family MFS_1 PF07690.16 CBZ29870.1 - 9.3e-09 34.7 30.6 3.5e-08 32.8 10.1 2.6 2 1 0 2 2 2 2 Major Facilitator Superfamily Ribosomal_L6e PF01159.19 CBZ29871.1 - 1.6e-29 102.7 3.1 1.7e-29 102.6 0.4 2.1 2 1 0 2 2 2 1 Ribosomal protein L6e KOW PF00467.29 CBZ29871.1 - 0.00098 19.0 0.0 0.0037 17.2 0.0 2.0 1 1 1 2 2 2 1 KOW motif WD40 PF00400.32 CBZ29872.1 - 4.1e-14 52.7 10.4 9e-06 26.3 0.2 4.8 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBZ29872.1 - 0.0084 16.4 0.0 19 5.6 0.0 3.7 2 1 1 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain PQQ_3 PF13570.6 CBZ29872.1 - 0.73 10.4 5.2 5.1 7.7 0.0 4.4 5 0 0 5 5 5 0 PQQ-like domain Spc7_N PF15402.6 CBZ29873.1 - 0.029 12.7 0.3 0.046 12.0 0.3 1.2 1 0 0 1 1 1 0 N-terminus of kinetochore NMS complex subunit Spc7 bact-PGI_C PF10432.9 CBZ29873.1 - 0.029 14.4 0.2 0.055 13.5 0.2 1.4 1 0 0 1 1 1 0 Bacterial phospho-glucose isomerase C-terminal SIS domain Vitelline_membr PF10542.9 CBZ29873.1 - 0.12 12.3 1.0 0.51 10.2 0.4 2.2 2 0 0 2 2 2 0 Vitelline membrane cysteine-rich region DUF2040 PF09745.9 CBZ29875.1 - 0.00072 19.6 0.2 0.0018 18.3 0.2 1.6 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 55 (DUF2040) SARAF PF06682.12 CBZ29875.1 - 0.021 14.5 4.4 0.88 9.2 0.6 2.1 1 1 1 2 2 2 0 SOCE-associated regulatory factor of calcium homoeostasis DUF4618 PF15397.6 CBZ29876.1 - 0.21 11.0 0.4 0.29 10.5 0.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4618) Cyclin PF08613.11 CBZ29877.1 - 2.6e-27 96.2 2.0 4.9e-27 95.3 0.1 2.5 2 1 0 2 2 2 1 Cyclin Cyclin_N PF00134.23 CBZ29877.1 - 8.8e-05 22.3 0.1 0.00015 21.5 0.1 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain NIF PF03031.18 CBZ29878.1 - 4.7e-20 71.9 0.0 2e-17 63.4 0.0 3.0 3 0 0 3 3 3 2 NLI interacting factor-like phosphatase Tubulin PF00091.25 CBZ29880.1 - 4e-68 229.5 0.0 6.5e-68 228.8 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 CBZ29880.1 - 1.6e-41 141.4 0.1 2.3e-41 140.9 0.1 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 CBZ29880.1 - 8.3e-05 22.9 0.0 0.00021 21.6 0.0 1.7 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.6 CBZ29880.1 - 0.0056 16.4 0.0 0.01 15.5 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain Tubulin_2 PF13809.6 CBZ29880.1 - 0.058 12.6 0.2 0.2 10.8 0.0 1.8 2 0 0 2 2 2 0 Tubulin like Tubulin PF00091.25 CBZ29881.1 - 5.3e-68 229.1 0.0 8.4e-68 228.5 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 CBZ29881.1 - 1.9e-41 141.2 0.1 2.8e-41 140.6 0.1 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 CBZ29881.1 - 0.0001 22.6 0.0 0.00024 21.4 0.0 1.6 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.6 CBZ29881.1 - 0.0068 16.1 0.0 0.012 15.3 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain Tubulin_2 PF13809.6 CBZ29881.1 - 0.072 12.3 0.2 0.23 10.6 0.0 1.8 2 0 0 2 2 2 0 Tubulin like Oxidored_FMN PF00724.20 CBZ29882.1 - 1.2e-70 238.5 0.0 1.8e-70 237.9 0.0 1.3 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Pyr_redox_2 PF07992.14 CBZ29882.1 - 2.7e-21 76.1 2.6 5.7e-20 71.7 2.2 2.6 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 CBZ29882.1 - 2.2e-09 37.4 0.0 1.9e-08 34.4 0.0 2.6 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 CBZ29882.1 - 2.8e-09 37.4 0.1 0.0014 19.1 0.1 3.4 3 1 0 3 3 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 CBZ29882.1 - 3.2e-07 29.4 1.7 3.4e-06 26.0 0.1 2.8 4 0 0 4 4 4 1 HI0933-like protein K_oxygenase PF13434.6 CBZ29882.1 - 1.4e-06 27.7 0.3 0.004 16.3 0.1 3.0 2 1 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.24 CBZ29882.1 - 2.3e-06 27.4 3.4 3.9e-05 23.4 0.1 3.6 4 0 0 4 4 4 1 FAD dependent oxidoreductase FAD_oxidored PF12831.7 CBZ29882.1 - 1.9e-05 24.2 0.1 3.2e-05 23.5 0.1 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 CBZ29882.1 - 4.8e-05 22.8 2.3 0.0097 15.2 0.1 3.0 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 CBZ29882.1 - 9e-05 21.7 0.8 0.00029 20.0 0.6 2.0 1 1 1 2 2 2 1 Glucose inhibited division protein A NAD_binding_9 PF13454.6 CBZ29882.1 - 0.00023 21.2 1.3 0.077 13.0 0.0 3.0 3 0 0 3 3 3 1 FAD-NAD(P)-binding FAD_binding_2 PF00890.24 CBZ29882.1 - 0.00024 20.3 3.2 0.00028 20.1 0.1 2.5 3 0 0 3 3 3 1 FAD binding domain 3HCDH_N PF02737.18 CBZ29882.1 - 0.00047 20.1 0.8 0.14 12.0 0.1 2.5 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_7 PF13241.6 CBZ29882.1 - 0.0006 20.2 0.1 0.12 12.8 0.0 2.5 2 0 0 2 2 2 1 Putative NAD(P)-binding FMO-like PF00743.19 CBZ29882.1 - 0.0025 16.3 0.2 3.8 5.8 0.0 3.0 2 1 0 3 3 3 1 Flavin-binding monooxygenase-like NAD_Gly3P_dh_N PF01210.23 CBZ29882.1 - 0.0033 17.4 0.0 0.12 12.3 0.0 2.4 2 0 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus FAD_binding_3 PF01494.19 CBZ29882.1 - 0.0041 16.4 0.4 0.057 12.6 0.1 2.2 2 0 0 2 2 2 1 FAD binding domain Thi4 PF01946.17 CBZ29882.1 - 0.023 13.9 0.2 0.063 12.5 0.0 1.7 2 0 0 2 2 2 0 Thi4 family Sacchrp_dh_NADP PF03435.18 CBZ29882.1 - 0.088 13.1 0.9 21 5.4 0.0 3.0 3 0 0 3 3 3 0 Saccharopine dehydrogenase NADP binding domain AlaDh_PNT_C PF01262.21 CBZ29882.1 - 0.096 12.0 0.6 0.2 10.9 0.0 1.8 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_2 PF03446.15 CBZ29882.1 - 0.12 12.5 0.0 15 5.7 0.0 3.0 3 0 0 3 3 3 0 NAD binding domain of 6-phosphogluconate dehydrogenase Amino_oxidase PF01593.24 CBZ29882.1 - 0.12 11.6 0.1 0.27 10.4 0.0 1.6 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase TrkA_N PF02254.18 CBZ29882.1 - 0.15 12.3 0.0 47 4.3 0.0 3.2 3 0 0 3 3 3 0 TrkA-N domain DFF-C PF09033.10 CBZ29883.1 - 0.55 10.1 3.8 13 5.7 0.2 2.9 3 0 0 3 3 3 0 DNA Fragmentation factor 45kDa, C terminal domain Pes-10 PF07149.11 CBZ29884.1 - 0.15 11.1 0.9 0.21 10.6 0.9 1.1 1 0 0 1 1 1 0 Pes-10 Sulfotransfer_4 PF17784.1 CBZ29885.1 - 1.1e-46 159.4 0.0 1.7e-46 158.8 0.0 1.3 1 0 0 1 1 1 1 Sulfotransferase domain Pol_alpha_B_N PF08418.10 CBZ29886.1 - 5.2 7.0 7.6 1.2 9.1 1.8 2.1 2 0 0 2 2 2 0 DNA polymerase alpha subunit B N-terminal DUF3392 PF11872.8 CBZ29887.1 - 0.014 15.7 0.6 0.033 14.5 0.6 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3392) zf-Tim10_DDP PF02953.15 CBZ29888.1 - 0.018 14.7 4.3 0.1 12.2 0.2 2.5 3 0 0 3 3 3 0 Tim10/DDP family zinc finger DnaJ PF00226.31 CBZ29889.1 - 8.7e-22 77.0 0.4 1.3e-21 76.4 0.4 1.3 1 0 0 1 1 1 1 DnaJ domain DUF1180 PF06679.12 CBZ29889.1 - 1.2 9.5 4.4 6.7 7.1 0.0 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1180) Shisa PF13908.6 CBZ29889.1 - 4.3 7.5 6.2 0.64 10.2 0.2 2.7 4 0 0 4 4 4 0 Wnt and FGF inhibitory regulator Ribosomal_S3_C PF00189.20 CBZ29891.1 - 1.4e-19 70.4 1.8 1.4e-19 70.4 1.8 2.2 2 1 1 3 3 3 1 Ribosomal protein S3, C-terminal domain KH_2 PF07650.17 CBZ29891.1 - 9.5e-08 31.8 0.2 2.6e-07 30.3 0.2 1.7 2 0 0 2 2 2 1 KH domain Rrn6 PF10214.9 CBZ29893.1 - 9.3 4.6 12.6 0.44 9.0 3.3 2.1 2 0 0 2 2 2 0 RNA polymerase I-specific transcription-initiation factor FIBP PF05427.11 CBZ29894.1 - 1e-07 31.6 0.1 0.00042 19.7 0.0 2.6 3 0 0 3 3 3 2 Acidic fibroblast growth factor binding (FIBP) SOBP PF15279.6 CBZ29894.1 - 0.15 12.7 17.6 0.36 11.4 17.6 1.7 1 0 0 1 1 1 0 Sine oculis-binding protein ANAPC4_WD40 PF12894.7 CBZ29895.1 - 3.2e-05 24.2 0.1 3.5 8.0 0.0 4.9 4 1 1 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 CBZ29895.1 - 0.00045 21.0 6.5 0.99 10.4 0.1 6.0 7 0 0 7 7 7 2 WD domain, G-beta repeat PQQ_3 PF13570.6 CBZ29895.1 - 0.16 12.5 8.5 23 5.7 0.1 6.3 6 0 0 6 6 6 0 PQQ-like domain NAPRTase PF04095.16 CBZ29896.1 - 7.9e-71 238.5 0.0 1e-70 238.1 0.0 1.1 1 0 0 1 1 1 1 Nicotinate phosphoribosyltransferase (NAPRTase) family NAPRTase_N PF17767.1 CBZ29896.1 - 7.1e-38 129.8 0.1 1.6e-37 128.7 0.1 1.6 1 0 0 1 1 1 1 Nicotinate phosphoribosyltransferase (NAPRTase) N-terminal domain SAM_2 PF07647.17 CBZ29896.1 - 0.11 12.6 0.0 0.59 10.3 0.0 2.2 2 0 0 2 2 2 0 SAM domain (Sterile alpha motif) CID_GANP PF16766.5 CBZ29897.1 - 0.27 11.5 3.1 7.5 6.8 0.1 2.5 2 0 0 2 2 2 0 Binding region of GANP to ENY2 SWIRM-assoc_2 PF16496.5 CBZ29897.1 - 0.29 10.0 4.7 0.49 9.2 4.7 1.4 1 0 0 1 1 1 0 SWIRM-associated domain at the N-terminal Skp1 PF01466.19 CBZ29898.1 - 0.00041 20.4 0.1 0.00064 19.8 0.1 1.3 1 0 0 1 1 1 1 Skp1 family, dimerisation domain DUF5588 PF17826.1 CBZ29898.1 - 0.13 11.1 0.0 0.15 10.9 0.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5588) Rhodanese PF00581.20 CBZ29899.1 - 6.5e-09 36.3 0.0 8.7e-09 35.9 0.0 1.1 1 0 0 1 1 1 1 Rhodanese-like domain DAGAT PF03982.13 CBZ29900.1 - 2.9e-18 65.8 0.0 4e-11 42.4 0.0 4.1 4 0 0 4 4 4 3 Diacylglycerol acyltransferase Pet100 PF09803.9 CBZ29900.1 - 0.52 10.9 3.1 16 6.1 0.1 3.1 3 0 0 3 3 3 0 Pet100 Cation_ATPase_C PF00689.21 CBZ29901.1 - 3.5e-40 137.6 5.4 3.5e-40 137.6 5.4 2.3 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 CBZ29901.1 - 4.3e-31 107.8 2.5 1.1e-30 106.4 2.5 1.7 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.26 CBZ29901.1 - 4.1e-11 43.6 0.0 0.023 15.0 0.0 3.3 3 0 0 3 3 3 3 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 CBZ29901.1 - 9.5e-08 32.0 0.0 2.1e-07 31.0 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 CBZ29901.1 - 1.9e-07 30.6 0.0 4.3e-07 29.5 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 CBZ29901.1 - 9.3e-05 22.3 0.3 0.00016 21.5 0.3 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase PSP1 PF04468.12 CBZ29902.1 - 1.3e-12 47.8 0.0 3.2e-12 46.6 0.0 1.6 1 0 0 1 1 1 1 PSP1 C-terminal conserved region PPTA PF01239.22 CBZ29903.1 - 1.4e-26 91.3 18.1 2.6e-08 33.3 0.6 5.6 6 0 0 6 6 6 5 Protein prenyltransferase alpha subunit repeat OCRE PF17780.1 CBZ29904.1 - 0.0008 19.4 6.0 0.0014 18.6 6.0 1.3 1 0 0 1 1 1 1 OCRE domain Peptidase_S9 PF00326.21 CBZ29906.1 - 0.038 13.4 0.0 0.064 12.7 0.0 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family AMP-binding_C PF13193.6 CBZ29906.1 - 0.15 13.1 0.5 0.44 11.5 0.2 2.0 1 1 1 2 2 2 0 AMP-binding enzyme C-terminal domain Voltage_CLC PF00654.20 CBZ29907.1 - 3e-97 326.1 29.0 3.2e-96 322.7 25.3 2.2 2 0 0 2 2 2 2 Voltage gated chloride channel CBS PF00571.28 CBZ29907.1 - 3.6e-10 40.1 1.8 4.3e-06 27.1 0.1 2.9 3 0 0 3 3 3 2 CBS domain Gly-zipper_YMGG PF13441.6 CBZ29907.1 - 1.2 9.0 6.1 13 5.6 0.0 2.6 2 0 0 2 2 2 0 YMGG-like Gly-zipper YEATS PF03366.16 CBZ29909.1 - 5.4e-09 35.9 0.0 9.6e-09 35.1 0.0 1.4 1 0 0 1 1 1 1 YEATS family PSK_trans_fac PF07704.11 CBZ29909.1 - 0.63 10.8 7.2 1.5 9.7 1.8 2.7 3 0 0 3 3 3 0 Rv0623-like transcription factor Guanylate_kin PF00625.21 CBZ29910.1 - 4.1e-48 163.5 0.0 4.8e-48 163.3 0.0 1.0 1 0 0 1 1 1 1 Guanylate kinase AAA_18 PF13238.6 CBZ29910.1 - 2.3e-06 28.2 0.2 5.3e-06 27.0 0.2 1.6 1 1 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.23 CBZ29910.1 - 8.1e-06 25.9 0.0 1.5e-05 25.1 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_33 PF13671.6 CBZ29910.1 - 3.2e-05 24.1 0.2 0.00016 21.9 0.2 1.9 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.6 CBZ29910.1 - 0.00065 20.0 0.0 0.0029 17.9 0.0 2.0 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.6 CBZ29910.1 - 0.0023 18.3 0.1 0.0028 18.1 0.1 1.6 1 1 0 1 1 1 1 AAA ATPase domain RsgA_GTPase PF03193.16 CBZ29910.1 - 0.0026 17.7 0.0 0.0045 16.9 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase AAA_17 PF13207.6 CBZ29910.1 - 0.0035 17.8 1.9 0.075 13.5 0.4 2.8 1 1 1 2 2 2 1 AAA domain dNK PF01712.19 CBZ29910.1 - 0.0052 16.7 0.1 0.21 11.4 0.1 2.1 1 1 0 1 1 1 1 Deoxynucleoside kinase AAA_5 PF07728.14 CBZ29910.1 - 0.032 14.2 0.0 0.11 12.5 0.0 1.9 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) Rad17 PF03215.15 CBZ29910.1 - 0.033 14.1 0.0 0.052 13.5 0.0 1.4 1 1 0 1 1 1 0 Rad17 P-loop domain ADK PF00406.22 CBZ29910.1 - 0.038 14.1 0.3 2 8.5 0.1 2.2 2 0 0 2 2 2 0 Adenylate kinase ABC_tran PF00005.27 CBZ29910.1 - 0.082 13.4 0.1 0.18 12.3 0.1 1.9 1 1 0 1 1 1 0 ABC transporter zf-CW PF07496.15 CBZ29911.1 - 5.6e-13 48.7 17.3 4.9e-09 36.1 7.7 3.8 3 0 0 3 3 3 3 CW-type Zinc Finger Yippee-Mis18 PF03226.14 CBZ29912.1 - 0.00021 21.4 0.7 0.76 10.0 0.2 2.7 2 0 0 2 2 2 2 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly RIG-I_C-RD PF11648.8 CBZ29912.1 - 0.12 12.6 1.4 1 9.6 0.0 2.4 2 0 0 2 2 2 0 C-terminal domain of RIG-I Nup88 PF10168.9 CBZ29912.1 - 0.3 8.8 12.3 0.41 8.4 12.3 1.1 1 0 0 1 1 1 0 Nuclear pore component DUF16 PF01519.16 CBZ29912.1 - 4.8 7.7 13.9 34 5.0 14.0 2.3 1 1 0 1 1 1 0 Protein of unknown function DUF16 SlyX PF04102.12 CBZ29912.1 - 7.3 7.3 19.9 1.1 10.0 3.2 3.6 2 1 1 3 3 3 0 SlyX TIG PF01833.24 CBZ29915.1 - 0.0009 19.3 1.5 0.2 11.7 0.2 3.4 3 0 0 3 3 3 1 IPT/TIG domain NPCBM_assoc PF10633.9 CBZ29915.1 - 0.015 15.6 2.4 4.6 7.6 0.2 2.7 2 0 0 2 2 2 0 NPCBM-associated, NEW3 domain of alpha-galactosidase Phage_holin_3_6 PF07332.11 CBZ29915.1 - 0.11 12.6 0.1 0.11 12.6 0.1 1.9 2 0 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III Big_3_4 PF13754.6 CBZ29915.1 - 0.13 12.0 0.0 0.27 11.0 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function RhodobacterPufX PF11511.8 CBZ29915.1 - 2.7 7.7 4.9 8.4 6.1 4.9 1.8 1 0 0 1 1 1 0 Intrinsic membrane protein PufX PUF PF00806.19 CBZ29916.1 - 9.8e-50 163.5 5.3 5.5e-06 25.8 0.1 8.4 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat FliC_SP PF12613.8 CBZ29917.1 - 1.7 9.2 6.3 0.98 10.0 4.1 1.7 2 0 0 2 2 2 0 Flagellin structural protein Ax_dynein_light PF10211.9 CBZ29919.1 - 2.4e-44 151.5 11.1 3.2e-44 151.1 11.1 1.1 1 0 0 1 1 1 1 Axonemal dynein light chain AAA PF00004.29 CBZ29921.1 - 9.9e-14 51.9 0.1 2.8e-09 37.5 0.0 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 CBZ29921.1 - 1e-05 25.5 0.0 5.9e-05 23.1 0.0 2.3 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 CBZ29921.1 - 3.7e-05 24.2 1.1 0.00022 21.7 0.1 2.7 3 1 0 3 3 3 1 AAA ATPase domain AAA_33 PF13671.6 CBZ29921.1 - 0.00085 19.5 0.0 0.0033 17.6 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.6 CBZ29921.1 - 0.0013 19.0 0.0 0.014 15.6 0.0 2.5 2 0 0 2 2 2 1 AAA domain RuvB_N PF05496.12 CBZ29921.1 - 0.012 15.4 0.0 0.024 14.4 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_11 PF13086.6 CBZ29921.1 - 0.018 14.9 4.5 0.1 12.4 0.0 2.8 3 0 0 3 3 3 0 AAA domain AAA_18 PF13238.6 CBZ29921.1 - 0.019 15.5 0.1 0.095 13.3 0.0 2.3 3 0 0 3 3 3 0 AAA domain AAA_30 PF13604.6 CBZ29921.1 - 0.021 14.5 0.0 0.077 12.7 0.0 1.9 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 CBZ29921.1 - 0.022 14.5 0.0 0.052 13.3 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_25 PF13481.6 CBZ29921.1 - 0.029 13.9 0.0 0.069 12.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain ATPase PF06745.13 CBZ29921.1 - 0.063 12.6 0.0 0.19 11.0 0.0 1.8 1 0 0 1 1 1 0 KaiC NB-ARC PF00931.22 CBZ29921.1 - 0.071 12.3 0.0 0.12 11.5 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain Mg_chelatase PF01078.21 CBZ29921.1 - 0.071 12.5 0.0 0.16 11.3 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.22 CBZ29921.1 - 0.081 13.3 0.1 0.69 10.3 0.0 2.5 3 0 0 3 3 2 0 RNA helicase AAA_24 PF13479.6 CBZ29921.1 - 0.083 12.6 0.0 0.16 11.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 CBZ29921.1 - 0.11 12.4 0.1 0.42 10.5 0.0 2.0 2 0 0 2 2 2 0 NACHT domain AAA_19 PF13245.6 CBZ29921.1 - 0.11 12.8 0.1 0.33 11.3 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.6 CBZ29921.1 - 0.2 12.1 0.9 6.6 7.2 0.1 2.9 2 1 0 2 2 2 0 AAA domain PPR_2 PF13041.6 CBZ29922.1 - 4.1e-05 23.7 0.2 0.00025 21.2 0.1 2.3 3 0 0 3 3 3 1 PPR repeat family PPR PF01535.20 CBZ29922.1 - 0.0006 19.9 0.1 1.9 8.9 0.0 3.5 3 0 0 3 3 3 2 PPR repeat TPR_19 PF14559.6 CBZ29922.1 - 0.017 15.6 0.2 0.13 12.8 0.0 2.6 3 0 0 3 3 3 0 Tetratricopeptide repeat PPR_3 PF13812.6 CBZ29922.1 - 0.038 14.1 0.0 0.096 12.8 0.0 1.6 1 0 0 1 1 1 0 Pentatricopeptide repeat domain CDC45 PF02724.14 CBZ29923.1 - 0.045 12.1 0.0 0.075 11.3 0.0 1.2 1 0 0 1 1 1 0 CDC45-like protein F-box PF00646.33 CBZ29923.1 - 0.08 12.9 0.1 0.2 11.6 0.1 1.7 1 0 0 1 1 1 0 F-box domain GcrA PF07750.11 CBZ29923.1 - 0.21 12.0 2.3 0.2 12.0 0.2 1.9 2 0 0 2 2 2 0 GcrA cell cycle regulator WD40 PF00400.32 CBZ29924.1 - 7.9e-11 42.4 10.3 1.3e-07 32.1 0.1 5.7 7 0 0 7 7 7 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBZ29924.1 - 7.5e-05 23.0 0.7 0.52 10.6 0.0 3.8 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain BBS2_Mid PF14783.6 CBZ29924.1 - 0.0009 19.3 0.3 14 5.7 0.0 5.2 4 1 1 5 5 5 1 Ciliary BBSome complex subunit 2, middle region CNH PF00780.22 CBZ29924.1 - 0.15 11.6 0.0 2.4 7.7 0.0 2.1 2 0 0 2 2 2 0 CNH domain SlyX PF04102.12 CBZ29924.1 - 0.25 12.0 1.5 2.1 9.0 0.1 2.6 2 0 0 2 2 2 0 SlyX WD40 PF00400.32 CBZ29925.1 - 3.6e-09 37.1 5.9 0.00027 21.7 0.1 4.8 4 0 0 4 4 4 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBZ29925.1 - 0.0031 17.8 0.0 27 5.1 0.0 3.6 2 1 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain CC2-LZ PF16516.5 CBZ29925.1 - 1.9 8.9 6.3 0.14 12.5 0.9 1.8 2 0 0 2 2 2 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator DUF4226 PF10774.9 CBZ29925.1 - 2.3 8.5 7.2 8.3 6.7 0.9 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4226) SOBP PF15279.6 CBZ29925.1 - 8.7 6.9 16.7 0.13 12.9 7.4 2.0 2 0 0 2 2 2 0 Sine oculis-binding protein CFC PF09443.10 CBZ29927.1 - 0.041 13.7 0.1 0.072 13.0 0.1 1.4 1 0 0 1 1 1 0 Cripto_Frl-1_Cryptic (CFC) Thioredoxin PF00085.20 CBZ29930.1 - 1.5e-08 34.6 0.2 2.3e-08 33.9 0.2 1.3 1 0 0 1 1 1 1 Thioredoxin YfmQ PF10787.9 CBZ29930.1 - 0.005 16.6 0.1 0.0065 16.2 0.1 1.2 1 0 0 1 1 1 1 Uncharacterised protein from bacillus cereus group Thioredoxin_8 PF13905.6 CBZ29930.1 - 0.0071 16.7 0.5 0.074 13.4 0.0 2.3 2 0 0 2 2 2 1 Thioredoxin-like Thioredoxin_2 PF13098.6 CBZ29930.1 - 0.037 14.5 0.5 0.097 13.1 0.2 1.8 1 1 1 2 2 2 0 Thioredoxin-like domain AhpC-TSA PF00578.21 CBZ29930.1 - 0.072 13.0 0.1 0.1 12.5 0.1 1.3 1 0 0 1 1 1 0 AhpC/TSA family Ribosomal_L29 PF00831.23 CBZ29930.1 - 0.16 12.0 3.0 7.5 6.6 0.1 2.6 2 0 0 2 2 2 0 Ribosomal L29 protein MFS_1_like PF12832.7 CBZ29931.1 - 6.5e-45 153.6 28.9 1.3e-44 152.7 28.9 1.5 1 1 0 1 1 1 1 MFS_1 like family MFS_1 PF07690.16 CBZ29931.1 - 2.9e-16 59.4 47.2 2.4e-09 36.6 25.6 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Nuc_H_symport PF03825.16 CBZ29931.1 - 9.2e-07 28.2 26.1 2e-06 27.1 26.1 1.5 1 1 0 1 1 1 1 Nucleoside H+ symporter LacY_symp PF01306.19 CBZ29931.1 - 4.5e-06 25.7 20.2 0.00026 19.9 20.2 2.2 1 1 0 1 1 1 1 LacY proton/sugar symporter DiS_P_DiS PF06750.13 CBZ29931.1 - 0.12 12.6 0.4 0.39 10.9 0.0 2.0 2 0 0 2 2 2 0 Bacterial Peptidase A24 N-terminal domain ABC1 PF03109.16 CBZ29932.1 - 3.4e-28 98.2 0.0 6.6e-28 97.3 0.0 1.5 1 0 0 1 1 1 1 ABC1 family APH PF01636.23 CBZ29932.1 - 0.0022 18.0 0.2 0.0096 15.9 0.2 2.1 1 1 0 1 1 1 1 Phosphotransferase enzyme family Pkinase PF00069.25 CBZ29932.1 - 0.0028 17.1 0.0 0.0053 16.1 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain RIO1 PF01163.22 CBZ29932.1 - 0.01 15.5 0.0 0.029 14.0 0.0 1.7 1 0 0 1 1 1 0 RIO1 family Cwf_Cwc_15 PF04889.12 CBZ29933.1 - 7.5e-08 32.4 7.3 1.4e-07 31.5 7.4 1.4 1 1 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein DUF3381 PF11861.8 CBZ29933.1 - 0.012 15.4 1.9 0.022 14.6 1.9 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3381) TFIIF_alpha PF05793.12 CBZ29933.1 - 0.072 11.7 11.3 0.076 11.6 11.3 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Sporozoite_P67 PF05642.11 CBZ29933.1 - 1.2 7.1 11.7 1.6 6.7 11.7 1.4 1 0 0 1 1 1 0 Sporozoite P67 surface antigen DUF4407 PF14362.6 CBZ29933.1 - 2.6 7.3 5.3 4.1 6.7 5.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Ndc1_Nup PF09531.10 CBZ29933.1 - 2.7 6.6 7.2 3.1 6.4 7.2 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Apt1 PF10351.9 CBZ29933.1 - 5 5.9 10.4 5.5 5.7 10.4 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain R3H PF01424.22 CBZ29934.1 - 0.059 13.4 0.1 0.14 12.2 0.1 1.6 1 0 0 1 1 1 0 R3H domain NADH_dhqG_C PF09326.11 CBZ29935.1 - 0.075 13.7 0.0 0.31 11.8 0.0 2.2 1 1 0 1 1 1 0 NADH-ubiquinone oxidoreductase subunit G, C-terminal Aminotran_1_2 PF00155.21 CBZ29936.1 - 2.4e-52 178.3 0.1 2.7e-52 178.2 0.1 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 CBZ29936.1 - 3.2e-06 26.4 0.5 6.7e-06 25.3 0.5 1.4 1 1 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.20 CBZ29936.1 - 9e-06 24.5 0.2 1.3e-05 23.9 0.2 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.17 CBZ29936.1 - 4.6e-05 22.9 0.1 7e-05 22.3 0.1 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family RNase_Zc3h12a PF11977.8 CBZ29936.1 - 0.0027 17.5 0.4 0.0098 15.7 0.4 1.8 1 1 0 1 1 1 1 Zc3h12a-like Ribonuclease NYN domain Beta_elim_lyase PF01212.21 CBZ29936.1 - 0.039 13.2 0.0 0.063 12.6 0.0 1.2 1 0 0 1 1 1 0 Beta-eliminating lyase Syntaxin PF00804.25 CBZ29937.1 - 4.1e-07 29.9 12.7 7e-07 29.1 12.7 1.4 1 0 0 1 1 1 1 Syntaxin SNARE PF05739.19 CBZ29937.1 - 5.8e-07 29.4 0.1 5.8e-07 29.4 0.1 1.9 2 0 0 2 2 2 1 SNARE domain GSCFA PF08885.11 CBZ29937.1 - 0.018 14.7 0.9 0.042 13.5 0.1 1.8 2 0 0 2 2 2 0 GSCFA family Ubiquitin_3 PF14836.6 CBZ29937.1 - 0.019 14.9 0.8 0.058 13.4 0.3 2.0 1 1 1 2 2 2 0 Ubiquitin-like domain Syntaxin_2 PF14523.6 CBZ29937.1 - 0.14 12.5 8.1 0.39 11.1 2.1 2.4 2 0 0 2 2 2 0 Syntaxin-like protein UPF0113 PF03657.13 CBZ29938.1 - 6.8e-19 67.9 0.0 1.6e-18 66.7 0.0 1.6 2 0 0 2 2 2 1 UPF0113 PUA domain UPF0113_N PF17833.1 CBZ29938.1 - 1.8e-18 66.9 0.0 2.8e-18 66.2 0.0 1.3 1 0 0 1 1 1 1 UPF0113 Pre-PUA domain DUF5317 PF17248.2 CBZ29938.1 - 0.063 13.3 0.0 0.1 12.6 0.0 1.3 1 1 0 1 1 1 0 Family of unknown function (DUF5317) Complex1_LYR PF05347.15 CBZ29939.1 - 6.2e-08 32.6 2.4 9.3e-08 32.0 2.4 1.3 1 0 0 1 1 1 1 Complex 1 protein (LYR family) HopJ PF08888.11 CBZ29939.1 - 0.013 15.8 0.0 0.026 14.7 0.0 1.6 1 1 0 1 1 1 0 HopJ type III effector protein DUF1416 PF07210.12 CBZ29939.1 - 0.027 14.4 0.0 0.03 14.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1416) Pkinase PF00069.25 CBZ29942.1 - 3.6e-65 219.9 0.0 4.7e-65 219.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ29942.1 - 1.9e-31 109.3 0.0 2.9e-31 108.7 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 CBZ29942.1 - 1.4e-05 24.6 0.3 2.9e-05 23.5 0.3 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 CBZ29942.1 - 0.00026 20.0 0.2 0.0004 19.4 0.2 1.3 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 CBZ29942.1 - 0.0029 17.0 0.0 0.0058 16.0 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 CBZ29942.1 - 0.0055 15.5 1.4 0.0058 15.4 0.2 1.7 2 0 0 2 2 2 1 Fungal protein kinase Seadorna_VP7 PF07387.11 CBZ29942.1 - 0.053 12.6 0.0 0.089 11.8 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 FTA2 PF13095.6 CBZ29942.1 - 0.073 12.7 0.0 0.16 11.6 0.0 1.6 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 MRP-L28 PF09812.9 CBZ29943.1 - 6.9e-05 23.0 0.1 0.00012 22.3 0.1 1.3 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L28 Pkinase PF00069.25 CBZ29944.1 - 1.4e-48 165.6 0.0 6.1e-28 97.9 0.0 3.4 3 0 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ29944.1 - 2.3e-29 102.5 0.2 2.1e-20 73.1 0.0 3.2 3 0 0 3 3 3 2 Protein tyrosine kinase FHA PF00498.26 CBZ29944.1 - 1e-09 38.6 0.1 0.0011 19.3 0.0 2.7 2 0 0 2 2 2 2 FHA domain Yop-YscD_cpl PF16697.5 CBZ29944.1 - 5.1e-05 23.5 0.0 0.00057 20.2 0.0 2.4 2 0 0 2 2 2 1 Inner membrane component of T3SS, cytoplasmic domain Kinase-like PF14531.6 CBZ29944.1 - 8.8e-05 22.0 5.1 0.00072 19.0 0.1 2.5 3 0 0 3 3 3 2 Kinase-like RIO1 PF01163.22 CBZ29944.1 - 0.001 18.7 0.0 0.002 17.7 0.0 1.4 1 0 0 1 1 1 1 RIO1 family APH PF01636.23 CBZ29944.1 - 0.0059 16.6 0.0 0.13 12.2 0.0 2.9 2 1 1 3 3 3 1 Phosphotransferase enzyme family WD40 PF00400.32 CBZ29945.1 - 2.9e-15 56.4 17.8 0.00053 20.7 0.1 6.6 7 0 0 7 7 6 3 WD domain, G-beta repeat Nup160 PF11715.8 CBZ29945.1 - 0.0002 20.2 6.0 0.25 9.9 0.1 3.8 2 1 2 4 4 4 2 Nucleoporin Nup120/160 CCDC106 PF15794.5 CBZ29945.1 - 0.00053 19.8 0.0 0.00053 19.8 0.0 2.3 2 0 0 2 2 2 1 Coiled-coil domain-containing protein 106 BLOC1_2 PF10046.9 CBZ29945.1 - 0.0027 18.0 1.9 0.0027 18.0 1.9 2.8 1 1 2 3 3 3 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 GCK PF07802.11 CBZ29945.1 - 0.0057 17.0 0.2 0.014 15.8 0.2 1.7 1 0 0 1 1 1 1 GCK domain CALCOCO1 PF07888.11 CBZ29945.1 - 0.02 13.8 25.4 0.029 13.3 25.4 1.1 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like PQQ_3 PF13570.6 CBZ29945.1 - 0.04 14.4 0.0 0.32 11.5 0.0 2.5 2 0 0 2 2 2 0 PQQ-like domain OmpH PF03938.14 CBZ29945.1 - 0.049 14.0 24.8 0.27 11.6 9.8 2.5 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) Nucleoporin_N PF08801.11 CBZ29945.1 - 0.089 11.5 0.1 0.42 9.3 0.1 2.0 1 1 0 1 1 1 0 Nup133 N terminal like Phage_GP20 PF06810.11 CBZ29945.1 - 0.12 12.2 0.2 0.12 12.2 0.2 2.4 1 1 2 3 3 3 0 Phage minor structural protein GP20 HOOK PF05622.12 CBZ29945.1 - 0.13 10.4 27.4 0.27 9.4 27.3 1.5 1 1 0 1 1 1 0 HOOK protein TPR_MLP1_2 PF07926.12 CBZ29945.1 - 0.24 11.4 26.2 0.16 12.1 11.9 2.3 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein Ses_B PF17046.5 CBZ29945.1 - 0.24 11.4 1.5 0.46 10.5 1.5 1.4 1 0 0 1 1 1 0 SesB domain on fungal death-pathway protein SLATT_fungal PF18142.1 CBZ29945.1 - 0.34 10.9 9.2 0.13 12.2 1.8 2.5 1 1 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain CENP-F_leu_zip PF10473.9 CBZ29945.1 - 0.72 9.9 29.0 0.084 12.9 0.7 3.2 1 1 2 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 NHL PF01436.21 CBZ29945.1 - 0.91 9.7 2.6 39 4.5 0.1 3.4 3 0 0 3 3 3 0 NHL repeat ATG16 PF08614.11 CBZ29945.1 - 0.94 9.7 35.2 2.6 8.2 29.5 3.2 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) TMF_TATA_bd PF12325.8 CBZ29945.1 - 1.1 9.5 28.0 0.069 13.4 6.0 2.6 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding YabA PF06156.13 CBZ29945.1 - 5.4 7.7 19.7 5.4 7.7 0.7 3.3 1 1 2 3 3 3 0 Initiation control protein YabA Fez1 PF06818.15 CBZ29945.1 - 5.8 7.3 26.2 1.1 9.7 9.4 2.3 1 1 1 2 2 2 0 Fez1 DUF1664 PF07889.12 CBZ29945.1 - 6.2 6.9 7.9 1.6 8.8 1.9 2.6 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) AAA_13 PF13166.6 CBZ29945.1 - 6.3 5.3 15.2 8.4 4.9 15.2 1.1 1 0 0 1 1 1 0 AAA domain FUSC PF04632.12 CBZ29945.1 - 7.2 5.0 19.7 12 4.2 19.7 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family Tropomyosin_1 PF12718.7 CBZ29945.1 - 8.9 6.5 27.6 0.073 13.2 11.7 2.3 1 1 1 2 2 2 0 Tropomyosin like Jnk-SapK_ap_N PF09744.9 CBZ29945.1 - 9.2 6.5 30.1 2.8 8.1 6.7 2.9 1 1 2 3 3 3 0 JNK_SAPK-associated protein-1 Aa_trans PF01490.18 CBZ29946.1 - 7.2e-50 169.9 18.5 9.3e-50 169.5 18.5 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 CBZ29946.1 - 5.4e-11 42.2 19.2 1.9e-09 37.0 13.1 2.8 2 1 0 2 2 2 2 Tryptophan/tyrosine permease family RRM_1 PF00076.22 CBZ29948.1 - 2.3e-08 33.7 0.0 8.6e-05 22.3 0.0 2.3 1 1 1 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.22 CBZ29949.1 - 2.7e-13 49.5 0.0 2.1e-09 37.0 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 CBZ29949.1 - 0.00067 19.2 0.1 0.0013 18.3 0.1 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CBZ29949.1 - 0.0075 16.4 0.0 0.013 15.6 0.0 1.5 1 1 0 1 1 1 1 RNA recognition motif RRM_1 PF00076.22 CBZ29950.1 - 1.8e-10 40.5 0.0 6.6e-10 38.7 0.0 1.9 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 CBZ29950.1 - 0.0014 18.2 0.0 0.0074 15.9 0.0 2.0 1 1 1 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RNA_bind PF08675.11 CBZ29950.1 - 0.0022 18.0 0.0 0.0062 16.5 0.0 1.7 2 0 0 2 2 2 1 RNA binding domain CbiK PF06180.11 CBZ29950.1 - 0.22 10.8 0.0 0.41 9.9 0.0 1.5 1 1 1 2 2 2 0 Cobalt chelatase (CbiK) RRM_1 PF00076.22 CBZ29951.1 - 2.2e-16 59.4 0.0 3.7e-16 58.7 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CBZ29951.1 - 0.11 12.6 0.0 0.16 12.1 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif TPR_12 PF13424.6 CBZ29952.1 - 5.3e-07 29.8 21.1 4.1e-05 23.8 1.5 6.0 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_1 PF00515.28 CBZ29952.1 - 0.00071 19.3 12.9 0.44 10.4 0.2 5.8 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_2 PF07719.17 CBZ29952.1 - 0.0092 16.0 16.1 7.1 7.0 0.0 7.3 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_7 PF13176.6 CBZ29952.1 - 0.012 15.6 0.7 7.6 6.8 0.0 4.1 3 0 0 3 3 3 0 Tetratricopeptide repeat ubiquitin PF00240.23 CBZ29953.1 - 0.00028 20.6 0.3 0.52 10.1 0.0 3.0 3 1 0 3 3 3 2 Ubiquitin family C2 PF00168.30 CBZ29953.1 - 0.052 13.9 0.2 0.23 11.8 0.0 2.1 2 0 0 2 2 2 0 C2 domain TPR_19 PF14559.6 CBZ29954.1 - 0.091 13.3 2.3 0.83 10.2 0.1 3.5 4 0 0 4 4 4 0 Tetratricopeptide repeat PRA1 PF03208.19 CBZ29955.1 - 1e-18 67.3 2.4 1e-18 67.3 2.4 1.4 2 0 0 2 2 2 1 PRA1 family protein PRA1 PF03208.19 CBZ29956.1 - 1.3e-26 93.0 8.3 1.9e-26 92.4 8.3 1.2 1 0 0 1 1 1 1 PRA1 family protein FA_hydroxylase PF04116.13 CBZ29956.1 - 0.97 9.8 5.3 3.4 8.0 0.1 2.3 2 1 0 2 2 2 0 Fatty acid hydroxylase superfamily GST_C PF00043.25 CBZ29957.1 - 1.4e-14 54.0 0.0 2.4e-14 53.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 CBZ29957.1 - 2.4e-07 30.9 0.0 3.6e-07 30.3 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 CBZ29957.1 - 3.7e-07 30.1 0.0 8.9e-07 28.8 0.0 1.5 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 CBZ29957.1 - 3.9e-07 30.3 0.0 7.2e-07 29.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain MetRS-N PF09635.10 CBZ29957.1 - 0.083 13.4 0.0 0.48 11.0 0.0 2.2 2 1 1 3 3 3 0 MetRS-N binding domain TauE PF01925.19 CBZ29959.1 - 3e-14 53.3 15.3 3.3e-08 33.4 6.3 2.3 2 0 0 2 2 2 2 Sulfite exporter TauE/SafE DUF3021 PF11457.8 CBZ29959.1 - 0.0047 17.3 4.7 0.0047 17.3 4.7 3.2 2 1 1 3 3 3 1 Protein of unknown function (DUF3021) DUF3611 PF12263.8 CBZ29959.1 - 0.022 14.7 3.9 0.12 12.3 0.7 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3611) DivIC PF04977.15 CBZ29959.1 - 0.028 14.2 0.1 0.073 12.8 0.1 1.6 1 0 0 1 1 1 0 Septum formation initiator DUF2244 PF10003.9 CBZ29959.1 - 0.077 12.7 0.3 0.077 12.7 0.3 2.7 4 0 0 4 4 4 0 Integral membrane protein (DUF2244) RseC_MucC PF04246.12 CBZ29959.1 - 0.094 12.7 8.6 0.12 12.3 0.3 2.9 3 0 0 3 3 3 0 Positive regulator of sigma(E), RseC/MucC DUF3278 PF11683.8 CBZ29959.1 - 0.56 10.3 3.6 1.9 8.6 1.3 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3278) MscS_TM PF12794.7 CBZ29959.1 - 1.6 7.5 9.0 0.075 11.9 0.3 2.5 2 1 0 2 2 2 0 Mechanosensitive ion channel inner membrane domain 1 Ribul_P_3_epim PF00834.19 CBZ29960.1 - 3.9e-59 199.4 0.1 4.6e-59 199.1 0.1 1.1 1 0 0 1 1 1 1 Ribulose-phosphate 3 epimerase family OMPdecase PF00215.24 CBZ29960.1 - 0.00044 19.9 0.0 0.0095 15.6 0.1 2.2 2 0 0 2 2 2 1 Orotidine 5'-phosphate decarboxylase / HUMPS family adh_short_C2 PF13561.6 CBZ29960.1 - 0.27 10.7 3.3 0.76 9.3 0.9 2.3 2 0 0 2 2 2 0 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 CBZ29963.1 - 3.5e-33 114.7 0.0 5.7e-33 114.0 0.0 1.3 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CBZ29963.1 - 2e-22 79.9 0.0 2.8e-22 79.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CBZ29963.1 - 3.3e-07 30.4 0.0 5e-07 29.8 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 CBZ29963.1 - 0.055 12.9 0.1 0.094 12.2 0.1 1.5 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 CBZ29963.1 - 0.072 12.2 0.0 0.11 11.6 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein 3HCDH_N PF02737.18 CBZ29963.1 - 0.09 12.7 0.0 0.17 11.8 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Staph_haemo PF05480.11 CBZ29964.1 - 0.13 12.0 0.3 0.31 10.8 0.3 1.6 1 0 0 1 1 1 0 Staphylococcus haemolytic protein Peptidase_M20 PF01546.28 CBZ29965.1 - 7.2e-18 65.0 0.0 1e-17 64.5 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 CBZ29965.1 - 3e-09 36.8 0.0 4.7e-09 36.1 0.0 1.3 1 0 0 1 1 1 1 Peptidase dimerisation domain HEAT PF02985.22 CBZ29966.1 - 6.9e-08 32.1 14.9 16 6.1 0.0 9.5 11 0 0 11 11 11 4 HEAT repeat HEAT_2 PF13646.6 CBZ29966.1 - 4.6e-06 26.9 2.4 0.059 13.8 0.1 5.7 5 2 2 7 7 7 2 HEAT repeats Cnd1 PF12717.7 CBZ29966.1 - 0.0011 19.0 7.7 1.7 8.7 0.0 5.1 7 0 0 7 7 7 2 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.7 CBZ29966.1 - 0.0029 18.2 3.2 0.78 10.4 0.1 4.5 4 1 0 4 4 4 1 Vacuolar 14 Fab1-binding region CLASP_N PF12348.8 CBZ29966.1 - 0.027 14.0 3.0 0.2 11.2 1.0 3.2 3 1 0 3 3 3 0 CLASP N terminal Adaptin_N PF01602.20 CBZ29966.1 - 0.1 11.1 0.7 0.57 8.7 0.4 2.5 2 0 0 2 2 2 0 Adaptin N terminal region TAF6_C PF07571.13 CBZ29966.1 - 0.12 12.7 0.4 62 4.0 0.0 4.0 4 0 0 4 4 4 0 TAF6 C-terminal HEAT repeat domain Pro_isomerase PF00160.21 CBZ29967.1 - 1.5e-44 152.0 0.0 1.8e-44 151.8 0.0 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD YfkB PF08756.10 CBZ29968.1 - 0.15 11.8 0.0 0.19 11.5 0.0 1.3 1 0 0 1 1 1 0 YfkB-like domain Monellin PF09200.10 CBZ29970.1 - 0.21 11.4 0.5 1.7 8.6 0.1 2.2 2 0 0 2 2 2 0 Monellin PIGA PF08288.12 CBZ29971.1 - 1e-37 128.6 0.1 2.2e-37 127.5 0.1 1.6 1 0 0 1 1 1 1 PIGA (GPI anchor biosynthesis) Glyco_transf_4 PF13439.6 CBZ29971.1 - 1.4e-27 96.7 0.2 2.6e-27 95.9 0.2 1.4 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glycos_transf_1 PF00534.20 CBZ29971.1 - 1.7e-27 96.0 0.0 2.6e-27 95.4 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 CBZ29971.1 - 1e-23 84.3 0.0 1.5e-23 83.7 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 CBZ29971.1 - 1.9e-12 47.9 0.0 3.8e-12 46.9 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_trans_4_2 PF13477.6 CBZ29971.1 - 0.00093 19.2 0.0 0.0081 16.2 0.0 2.2 2 0 0 2 2 2 1 Glycosyl transferase 4-like Glyco_trans_1_2 PF13524.6 CBZ29971.1 - 0.084 13.3 0.0 0.24 11.8 0.0 1.7 1 0 0 1 1 1 0 Glycosyl transferases group 1 ThiI PF02568.14 CBZ29972.1 - 3.8e-45 153.9 0.2 7e-45 153.0 0.2 1.3 1 0 0 1 1 1 1 Thiamine biosynthesis protein (ThiI) Aminotran_5 PF00266.19 CBZ29972.1 - 3.1e-27 95.5 0.4 2.8e-13 49.6 0.0 2.2 2 0 0 2 2 2 2 Aminotransferase class-V tRNA_Me_trans PF03054.16 CBZ29972.1 - 7.3e-05 21.7 0.1 0.00016 20.6 0.0 1.5 2 0 0 2 2 2 1 tRNA methyl transferase QueC PF06508.13 CBZ29972.1 - 0.0027 17.3 0.6 0.042 13.3 0.0 2.5 3 0 0 3 3 3 1 Queuosine biosynthesis protein QueC DNA_pol_B PF00136.21 CBZ29973.1 - 1.1e-137 459.5 0.0 1.5e-137 459.1 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.19 CBZ29973.1 - 1.3e-74 251.3 0.0 2.2e-74 250.6 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.6 CBZ29973.1 - 2.2e-17 63.3 8.5 5.7e-17 61.9 8.5 1.8 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta zinc-ribbons_6 PF07191.12 CBZ29973.1 - 0.04 13.9 5.7 0.63 10.1 0.2 2.7 2 0 0 2 2 2 0 zinc-ribbons DNA_pol_B_2 PF03175.13 CBZ29973.1 - 0.077 11.8 0.1 0.66 8.8 0.0 2.1 2 0 0 2 2 2 0 DNA polymerase type B, organellar and viral SNF2_N PF00176.23 CBZ29974.1 - 5.2e-71 239.2 0.4 6.6e-70 235.6 0.1 2.6 2 1 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.31 CBZ29974.1 - 3.1e-20 72.6 0.0 4.6e-19 68.8 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 CBZ29974.1 - 6.8e-09 36.0 0.0 2.2e-08 34.3 0.0 2.0 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SLIDE PF09111.10 CBZ29974.1 - 2.1e-07 31.0 0.4 5.6e-07 29.6 0.4 1.7 1 0 0 1 1 1 1 SLIDE HAND PF09110.11 CBZ29974.1 - 6.7e-06 26.8 6.6 2.4e-05 25.0 6.6 2.0 1 0 0 1 1 1 1 HAND DEAD PF00270.29 CBZ29974.1 - 0.00013 21.8 0.0 0.00058 19.7 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Pkinase PF00069.25 CBZ29975.1 - 9.2e-68 228.4 0.0 4.3e-67 226.3 0.0 1.9 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ29975.1 - 1.3e-39 136.1 0.4 1.8e-39 135.6 0.0 1.4 2 0 0 2 2 2 1 Protein tyrosine kinase EF-hand_7 PF13499.6 CBZ29975.1 - 1.9e-14 53.8 1.6 3.1e-08 33.9 0.5 2.7 2 0 0 2 2 2 2 EF-hand domain pair Kinase-like PF14531.6 CBZ29975.1 - 2.6e-10 40.1 0.0 1.1e-09 38.0 0.0 1.9 1 1 1 2 2 2 1 Kinase-like EF-hand_1 PF00036.32 CBZ29975.1 - 1.1e-09 37.1 0.8 0.082 12.5 0.1 4.5 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.6 CBZ29975.1 - 5.9e-09 35.1 1.2 0.044 13.7 0.0 5.4 3 1 1 4 4 4 2 EF-hand domain EF-hand_8 PF13833.6 CBZ29975.1 - 2.8e-06 27.1 2.1 0.03 14.2 0.1 2.7 2 0 0 2 2 2 2 EF-hand domain pair RIO1 PF01163.22 CBZ29975.1 - 2.1e-05 24.2 1.5 4.6e-05 23.1 1.5 1.5 1 0 0 1 1 1 1 RIO1 family Haspin_kinase PF12330.8 CBZ29975.1 - 0.00057 18.9 0.2 0.00092 18.2 0.2 1.3 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 CBZ29975.1 - 0.0012 18.2 0.2 0.0024 17.3 0.2 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.9 CBZ29975.1 - 0.0059 16.1 0.4 0.012 15.2 0.4 1.4 1 0 0 1 1 1 1 PhoP regulatory network protein YrbL EF-hand_5 PF13202.6 CBZ29975.1 - 0.039 13.5 0.7 44 3.8 0.0 4.0 3 0 0 3 3 3 0 EF hand MYO10_CC PF16735.5 CBZ29975.1 - 0.12 12.5 0.2 0.37 10.9 0.2 1.8 1 0 0 1 1 1 0 Unconventional myosin-X coiled coil domain Crystallin PF00525.18 CBZ29975.1 - 0.16 12.1 0.0 0.36 11.0 0.0 1.5 1 0 0 1 1 1 0 Alpha crystallin A chain, N terminal TPR_12 PF13424.6 CBZ29976.1 - 4.6e-17 62.1 11.9 1.7e-08 34.6 1.9 3.3 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.28 CBZ29976.1 - 8.2e-13 47.6 8.0 0.012 15.4 0.0 5.3 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_2 PF07719.17 CBZ29976.1 - 6.1e-10 38.4 11.5 0.066 13.3 0.0 6.2 6 0 0 6 6 6 4 Tetratricopeptide repeat ANAPC5 PF12862.7 CBZ29976.1 - 3.3e-05 23.9 3.5 0.022 14.8 0.0 2.7 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 5 TPR_8 PF13181.6 CBZ29976.1 - 0.0001 22.3 5.8 1.6 9.1 0.0 4.9 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_MalT PF17874.1 CBZ29976.1 - 0.00021 20.8 3.6 0.00093 18.7 2.8 2.0 2 0 0 2 2 2 1 MalT-like TPR region TPR_7 PF13176.6 CBZ29976.1 - 0.00059 19.7 7.6 22 5.4 0.0 5.6 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_9 PF13371.6 CBZ29976.1 - 0.004 17.3 2.3 0.85 9.8 0.1 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat RPN7 PF10602.9 CBZ29976.1 - 0.016 15.0 0.1 2 8.1 0.0 2.5 2 1 0 2 2 2 0 26S proteasome subunit RPN7 TPR_21 PF09976.9 CBZ29976.1 - 0.046 13.4 0.2 0.089 12.5 0.2 1.4 1 0 0 1 1 1 0 Tetratricopeptide repeat-like domain MIF PF01187.18 CBZ29978.1 - 1.5e-11 44.6 0.0 1.6e-11 44.5 0.0 1.1 1 0 0 1 1 1 1 Macrophage migration inhibitory factor (MIF) MIF PF01187.18 CBZ29979.1 - 4e-09 36.8 0.0 4.4e-09 36.6 0.0 1.1 1 0 0 1 1 1 1 Macrophage migration inhibitory factor (MIF) Topo_C_assoc PF14370.6 CBZ29979.1 - 0.016 15.1 0.0 0.03 14.2 0.0 1.4 1 0 0 1 1 1 0 C-terminal topoisomerase domain OTT_1508_deam PF14441.6 CBZ29980.1 - 0.0009 19.2 1.1 0.0018 18.3 0.1 2.0 2 0 0 2 2 2 1 OTT_1508-like deaminase LisH PF08513.11 CBZ29982.1 - 0.041 13.9 0.5 0.16 12.0 0.1 2.2 2 0 0 2 2 2 0 LisH Cnd2 PF05786.14 CBZ29982.1 - 2.9 6.4 13.0 4.9 5.7 13.0 1.2 1 0 0 1 1 1 0 Condensin complex subunit 2 DOT1 PF08123.13 CBZ29983.1 - 2.1e-14 53.6 0.0 2.9e-14 53.1 0.0 1.1 1 0 0 1 1 1 1 Histone methylation protein DOT1 Methyltransf_31 PF13847.6 CBZ29983.1 - 0.00058 19.7 0.0 0.00081 19.2 0.0 1.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.17 CBZ29983.1 - 0.012 15.1 0.1 0.1 12.0 0.0 2.1 1 1 0 2 2 2 0 Putative methyltransferase Methyltransf_23 PF13489.6 CBZ29983.1 - 0.031 14.1 0.0 0.041 13.7 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.12 CBZ29983.1 - 0.035 14.8 0.0 0.06 14.1 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_25 PF13649.6 CBZ29983.1 - 0.068 13.9 0.0 0.11 13.2 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_18 PF12847.7 CBZ29983.1 - 0.16 11.9 0.0 0.26 11.2 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain DER1 PF04511.15 CBZ29984.1 - 2.3e-31 109.2 11.7 2.8e-31 108.9 11.7 1.0 1 0 0 1 1 1 1 Der1-like family Oleosin PF01277.17 CBZ29984.1 - 0.0033 17.2 0.8 0.0033 17.2 0.8 2.0 2 1 1 3 3 3 1 Oleosin DUF373 PF04123.13 CBZ29984.1 - 3.2 7.1 6.6 6.6 6.1 1.2 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF373) Pkinase PF00069.25 CBZ29987.1 - 1.1e-48 165.9 0.0 1.5e-48 165.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ29987.1 - 5.1e-24 84.9 0.0 7.4e-24 84.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 CBZ29987.1 - 4.3e-05 23.5 0.0 0.0004 20.4 0.0 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family ABC1 PF03109.16 CBZ29987.1 - 0.19 11.9 0.0 0.36 11.0 0.0 1.3 1 0 0 1 1 1 0 ABC1 family Pox_ser-thr_kin PF05445.11 CBZ29987.1 - 0.19 10.7 0.0 0.31 10.0 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Ras PF00071.22 CBZ29988.1 - 1.2e-50 171.2 0.0 1.5e-50 171.0 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CBZ29988.1 - 6.7e-34 116.7 0.0 1.2e-33 115.8 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CBZ29988.1 - 4.2e-16 58.9 0.0 5e-16 58.6 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 CBZ29988.1 - 2.8e-06 26.9 0.0 3.9e-06 26.4 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 CBZ29988.1 - 1.3e-05 25.2 0.0 2.4e-05 24.4 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 CBZ29988.1 - 1.9e-05 24.6 0.5 0.0041 17.0 0.4 2.9 2 1 1 3 3 3 1 RsgA GTPase AAA_16 PF13191.6 CBZ29988.1 - 0.0022 18.4 0.2 0.0048 17.3 0.2 1.9 1 1 0 1 1 1 1 AAA ATPase domain AAA_24 PF13479.6 CBZ29988.1 - 0.0034 17.1 0.3 0.055 13.2 0.2 2.3 2 1 0 2 2 2 1 AAA domain ATP_bind_1 PF03029.17 CBZ29988.1 - 0.0075 16.1 0.2 0.03 14.1 0.0 1.8 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein GTP_EFTU PF00009.27 CBZ29988.1 - 0.0078 15.8 0.0 0.045 13.3 0.0 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain DAP3 PF10236.9 CBZ29988.1 - 0.012 14.8 0.0 0.019 14.1 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 AAA_29 PF13555.6 CBZ29988.1 - 0.015 15.1 1.2 0.049 13.4 1.2 1.9 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_7 PF12775.7 CBZ29988.1 - 0.015 14.8 0.1 0.046 13.2 0.1 1.8 2 0 0 2 2 2 0 P-loop containing dynein motor region MCM PF00493.23 CBZ29988.1 - 0.016 14.3 0.0 0.031 13.4 0.0 1.4 1 0 0 1 1 1 0 MCM P-loop domain AAA_25 PF13481.6 CBZ29988.1 - 0.017 14.7 0.6 1.6 8.2 0.1 2.3 2 1 0 2 2 2 0 AAA domain cobW PF02492.19 CBZ29988.1 - 0.026 14.1 0.0 0.24 11.0 0.0 2.1 1 1 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain SRPRB PF09439.10 CBZ29988.1 - 0.027 13.9 0.0 0.036 13.5 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_23 PF13476.6 CBZ29988.1 - 0.057 13.9 0.2 0.087 13.3 0.2 1.5 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.27 CBZ29988.1 - 0.059 13.9 0.9 0.14 12.6 0.4 1.8 2 1 0 2 2 2 0 ABC transporter G-alpha PF00503.20 CBZ29988.1 - 0.08 12.1 0.7 1.8 7.7 0.2 2.3 1 1 1 2 2 2 0 G-protein alpha subunit DUF815 PF05673.13 CBZ29988.1 - 0.09 11.9 0.2 0.19 10.8 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_22 PF13401.6 CBZ29988.1 - 0.11 12.7 0.1 0.56 10.5 0.1 2.1 1 1 0 1 1 1 0 AAA domain DNA_pol_E_B PF04042.16 CBZ29988.1 - 0.12 11.7 0.0 0.17 11.2 0.0 1.2 1 0 0 1 1 1 0 DNA polymerase alpha/epsilon subunit B AAA_5 PF07728.14 CBZ29988.1 - 0.16 12.0 0.0 0.47 10.4 0.0 1.8 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) YTH PF04146.15 CBZ29988.1 - 0.16 11.9 0.0 0.2 11.6 0.0 1.2 1 0 0 1 1 1 0 YT521-B-like domain Septin PF00735.18 CBZ29988.1 - 0.19 11.0 0.1 0.3 10.3 0.1 1.3 1 0 0 1 1 1 0 Septin eIF-5a PF01287.20 CBZ29989.1 - 0.043 13.9 0.1 0.08 13.1 0.1 1.4 1 0 0 1 1 1 0 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold ABC_membrane_2 PF06472.15 CBZ29990.1 - 2.1e-63 214.3 0.4 3e-63 213.8 0.4 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 ABC_tran PF00005.27 CBZ29990.1 - 4.3e-18 66.1 0.0 9.7e-18 65.0 0.0 1.6 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 CBZ29990.1 - 0.0027 17.6 0.1 0.0063 16.4 0.1 1.5 1 1 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 CBZ29990.1 - 0.0041 16.6 0.0 0.17 11.3 0.0 2.4 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 CBZ29990.1 - 0.006 16.3 0.1 0.015 15.1 0.1 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_23 PF13476.6 CBZ29990.1 - 0.011 16.3 0.0 0.02 15.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain DUF3584 PF12128.8 CBZ29990.1 - 0.013 13.0 0.5 0.02 12.4 0.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) NACHT PF05729.12 CBZ29990.1 - 0.029 14.3 0.1 0.33 10.9 0.0 2.6 3 0 0 3 3 3 0 NACHT domain Mg_chelatase PF01078.21 CBZ29990.1 - 0.037 13.4 0.1 0.089 12.2 0.1 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_30 PF13604.6 CBZ29990.1 - 0.039 13.7 0.1 0.079 12.7 0.1 1.4 1 0 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.18 CBZ29990.1 - 0.065 12.6 0.0 0.15 11.4 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family DLIC PF05783.11 CBZ29990.1 - 0.11 11.4 0.1 0.17 10.7 0.1 1.2 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) AAA_22 PF13401.6 CBZ29990.1 - 0.34 11.2 1.3 3.2 8.0 0.2 2.9 4 0 0 4 4 4 0 AAA domain NOG1_N PF17835.1 CBZ29991.1 - 1.2e-53 181.4 0.3 2.3e-53 180.4 0.3 1.5 1 0 0 1 1 1 1 NOG1 N-terminal helical domain NOG1 PF06858.14 CBZ29991.1 - 1.2e-27 95.5 0.0 3.5e-27 93.9 0.0 1.9 2 0 0 2 2 2 1 Nucleolar GTP-binding protein 1 (NOG1) NOGCT PF08155.11 CBZ29991.1 - 4.5e-23 81.0 5.7 1.1e-22 79.8 5.7 1.7 1 0 0 1 1 1 1 NOGCT (NUC087) domain MMR_HSR1 PF01926.23 CBZ29991.1 - 2.2e-17 63.2 0.0 5.2e-17 62.0 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 CBZ29991.1 - 3.7e-09 36.3 0.0 8.7e-09 35.1 0.0 1.5 1 1 0 1 1 1 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 CBZ29991.1 - 0.0017 18.3 0.0 1.5 8.7 0.0 2.8 2 1 0 2 2 2 2 RsgA GTPase AIG1 PF04548.16 CBZ29991.1 - 0.013 14.8 0.0 0.027 13.8 0.0 1.5 1 0 0 1 1 1 0 AIG1 family Dynamin_N PF00350.23 CBZ29991.1 - 0.077 13.0 0.1 6.2 6.8 0.0 2.5 1 1 1 2 2 2 0 Dynamin family IQ PF00612.27 CBZ29992.1 - 0.00053 19.5 0.1 0.0017 18.0 0.1 2.0 1 0 0 1 1 1 1 IQ calmodulin-binding motif NO_synthase PF02898.15 CBZ29992.1 - 0.11 11.5 0.0 0.2 10.7 0.0 1.3 1 0 0 1 1 1 0 Nitric oxide synthase, oxygenase domain FOP_dimer PF09398.10 CBZ29994.1 - 1.3e-11 44.6 0.0 2.3e-11 43.8 0.0 1.4 1 0 0 1 1 1 1 FOP N terminal dimerisation domain LisH_2 PF16045.5 CBZ29994.1 - 1.6e-05 23.8 0.0 2.6e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 LisH LisH PF08513.11 CBZ29994.1 - 0.012 15.5 0.1 0.024 14.6 0.1 1.5 1 0 0 1 1 1 0 LisH Snf7 PF03357.21 CBZ29995.1 - 5.9e-13 48.8 11.1 5.9e-13 48.8 11.1 1.9 1 1 1 2 2 2 1 Snf7 FtsK_alpha PF17854.1 CBZ29995.1 - 0.42 10.8 2.1 2.3 8.4 0.0 2.7 2 1 1 3 3 3 0 FtsK alpha domain CAF1C_H4-bd PF12265.8 CBZ29996.1 - 7.1e-12 45.4 0.0 1.6e-11 44.3 0.0 1.6 1 0 0 1 1 1 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex DUF2992 PF11208.8 CBZ29996.1 - 0.074 13.3 0.4 0.44 10.8 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2992) WD40 PF00400.32 CBZ29996.1 - 0.21 12.5 9.2 0.22 12.5 0.0 4.6 5 0 0 5 5 5 0 WD domain, G-beta repeat Cwf_Cwc_15 PF04889.12 CBZ29996.1 - 3.2 7.4 25.2 5.6 6.6 13.4 2.2 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein Pho88 PF10032.9 CBZ29997.1 - 3.6e-26 91.5 0.0 4.4e-26 91.3 0.0 1.0 1 0 0 1 1 1 1 Phosphate transport (Pho88) Pribosyltran_N PF13793.6 CBZ29998.1 - 2.1e-40 137.3 0.1 1.2e-39 134.9 0.0 2.1 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.6 CBZ29998.1 - 4.9e-23 82.1 1.1 3.3e-22 79.4 0.3 2.1 1 1 1 2 2 2 1 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.27 CBZ29998.1 - 4.1e-18 65.4 0.3 8.5e-18 64.4 0.3 1.5 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.6 CBZ29998.1 - 0.0036 16.8 0.1 0.0061 16.0 0.1 1.4 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase HHH_3 PF12836.7 CBZ29998.1 - 0.12 12.7 0.1 9.7 6.5 0.0 2.4 2 0 0 2 2 2 0 Helix-hairpin-helix motif PRORP PF16953.5 CBZ30000.1 - 1.6e-16 60.6 0.1 1.2e-11 44.6 0.1 4.5 4 1 0 4 4 4 2 Protein-only RNase P PPR_long PF17177.4 CBZ30000.1 - 6.7e-11 42.0 0.5 1.5e-10 40.9 0.5 1.5 1 0 0 1 1 1 1 Pentacotripeptide-repeat region of PRORP DUF3439 PF11921.8 CBZ30000.1 - 0.1 12.6 1.7 0.74 9.8 0.2 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) zf-RING_14 PF17978.1 CBZ30000.1 - 0.12 12.8 0.1 9.4 6.7 0.1 2.8 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain Ribosomal_L37e PF01907.19 CBZ30001.1 - 6.6e-25 87.0 8.5 1e-24 86.4 8.5 1.3 1 0 0 1 1 1 1 Ribosomal protein L37e Mg-por_mtran_C PF07109.11 CBZ30003.1 - 0.18 12.1 0.0 40 4.6 0.0 2.6 2 0 0 2 2 2 0 Magnesium-protoporphyrin IX methyltransferase C-terminus Pkinase PF00069.25 CBZ30004.1 - 8.5e-61 205.6 0.0 1.1e-60 205.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ30004.1 - 6.7e-39 133.7 0.0 8.8e-39 133.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase PH PF00169.29 CBZ30004.1 - 6.1e-08 33.1 0.0 4.1e-07 30.4 0.0 2.1 2 0 0 2 2 2 1 PH domain Kinase-like PF14531.6 CBZ30004.1 - 1.3e-07 31.2 0.0 2e-07 30.7 0.0 1.2 1 0 0 1 1 1 1 Kinase-like PH_11 PF15413.6 CBZ30004.1 - 0.00016 22.0 0.0 0.00044 20.6 0.0 1.8 1 1 0 1 1 1 1 Pleckstrin homology domain PH_9 PF15410.6 CBZ30004.1 - 0.0039 17.6 0.0 0.095 13.1 0.0 2.4 1 1 0 1 1 1 1 Pleckstrin homology domain Pkinase_fungal PF17667.1 CBZ30004.1 - 0.034 12.9 0.0 0.052 12.3 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase DUF1636 PF07845.11 CBZ30004.1 - 0.069 13.6 0.0 0.18 12.2 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1636) PH_3 PF14593.6 CBZ30004.1 - 0.071 13.2 0.0 0.24 11.5 0.0 1.9 1 1 0 1 1 1 0 PH domain PEN-2 PF10251.9 CBZ30006.1 - 7.4e-08 32.7 7.3 1.1e-07 32.1 7.2 1.4 1 1 0 1 1 1 1 Presenilin enhancer-2 subunit of gamma secretase 7tm_2 PF00002.24 CBZ30006.1 - 0.012 14.9 1.3 0.015 14.6 1.3 1.1 1 0 0 1 1 1 0 7 transmembrane receptor (Secretin family) Peptidase_C2 PF00648.21 CBZ30007.1 - 4.1e-34 117.9 0.0 6.9e-34 117.2 0.0 1.2 1 0 0 1 1 1 1 Calpain family cysteine protease Calpain_III PF01067.22 CBZ30007.1 - 4.7e-09 36.6 0.0 0.00021 21.5 0.0 3.7 4 0 0 4 4 4 2 Calpain large subunit, domain III MIT PF04212.18 CBZ30007.1 - 1.9e-08 34.2 0.2 5.3e-08 32.8 0.3 1.7 2 0 0 2 2 2 1 MIT (microtubule interacting and transport) domain Arm PF00514.23 CBZ30009.1 - 1.9e-05 24.5 2.5 1.4 9.1 0.0 5.2 4 0 0 4 4 4 3 Armadillo/beta-catenin-like repeat Nup84_Nup100 PF04121.13 CBZ30010.1 - 1.1e-07 30.4 0.0 0.0032 15.7 0.0 2.6 2 1 0 2 2 2 2 Nuclear pore protein 84 / 107 DUF383 PF04063.14 CBZ30011.1 - 0.0013 18.5 0.1 0.0086 15.8 0.0 2.2 2 1 0 2 2 2 1 Domain of unknown function (DUF383) HEAT PF02985.22 CBZ30011.1 - 0.048 13.9 0.6 4.8 7.7 0.0 4.0 5 0 0 5 5 5 0 HEAT repeat MMS19_N PF14500.6 CBZ30011.1 - 0.059 12.9 0.2 1.7 8.2 0.0 2.9 2 1 1 3 3 3 0 Dos2-interacting transcription regulator of RNA-Pol-II Arm_2 PF04826.13 CBZ30011.1 - 0.073 12.5 0.1 0.21 11.0 0.0 1.7 2 0 0 2 2 2 0 Armadillo-like Nucleoside_tran PF01733.18 CBZ30012.1 - 0.029 13.7 0.0 0.029 13.7 0.0 1.1 1 0 0 1 1 1 0 Nucleoside transporter Pkinase PF00069.25 CBZ30013.1 - 1.7e-46 158.8 0.0 6.2e-36 124.1 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ30013.1 - 5.3e-28 98.0 0.2 2.3e-19 69.7 0.2 3.1 2 1 0 2 2 2 2 Protein tyrosine kinase E1-E2_ATPase PF00122.20 CBZ30015.1 - 1.2e-44 152.0 0.9 1.2e-44 152.0 0.9 2.3 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.26 CBZ30015.1 - 7.7e-35 121.1 1.3 1.5e-34 120.2 0.5 1.9 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HMA PF00403.26 CBZ30015.1 - 4.7e-33 113.4 10.6 4.1e-16 59.2 0.1 3.8 4 0 0 4 4 4 3 Heavy-metal-associated domain Hydrolase_3 PF08282.12 CBZ30015.1 - 1.2e-06 28.5 0.2 1.7e-05 24.7 0.1 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 CBZ30015.1 - 0.0011 19.4 0.1 0.0026 18.2 0.1 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase CoA_binding_2 PF13380.6 CBZ30015.1 - 0.0084 16.6 2.0 0.014 15.9 0.4 2.3 2 0 0 2 2 2 1 CoA binding domain cpYpsA PF12694.7 CBZ30015.1 - 0.072 12.9 0.3 0.24 11.2 0.0 1.9 2 0 0 2 2 2 0 Circularly permutated YpsA SLOG family ProQ_C PF17516.2 CBZ30015.1 - 0.1 12.0 0.5 0.53 9.7 0.1 2.4 2 0 0 2 2 2 0 ProQ C-terminal domain RDD PF06271.12 CBZ30015.1 - 9.3 6.4 12.2 29 4.9 6.0 2.9 2 0 0 2 2 2 0 RDD family His_Phos_1 PF00300.22 CBZ30016.1 - 7.2e-29 100.9 0.1 8e-21 74.6 0.0 2.4 2 1 0 2 2 2 2 Histidine phosphatase superfamily (branch 1) His_Phos_1 PF00300.22 CBZ30017.1 - 7.8e-18 64.9 0.0 1.3e-09 38.1 0.0 2.2 2 0 0 2 2 2 2 Histidine phosphatase superfamily (branch 1) zf-HIT PF04438.16 CBZ30018.1 - 6.7e-07 29.1 12.9 1.3e-06 28.1 12.9 1.5 1 0 0 1 1 1 1 HIT zinc finger STI1 PF17830.1 CBZ30018.1 - 0.046 13.7 0.0 0.079 12.9 0.0 1.4 1 0 0 1 1 1 0 STI1 domain zf-MYND PF01753.18 CBZ30018.1 - 0.22 11.7 14.0 0.47 10.6 14.0 1.5 1 0 0 1 1 1 0 MYND finger zf-B_box PF00643.24 CBZ30018.1 - 0.25 11.5 6.6 0.48 10.6 6.6 1.4 1 0 0 1 1 1 0 B-box zinc finger Zf_RING PF16744.5 CBZ30018.1 - 0.72 10.0 7.1 1.7 8.8 7.1 1.7 1 0 0 1 1 1 0 KIAA1045 RING finger Kinesin PF00225.23 CBZ30020.1 - 1.6e-80 270.5 0.0 3.5e-80 269.4 0.0 1.5 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 CBZ30020.1 - 3.3e-23 82.3 0.0 8e-23 81.0 0.0 1.7 1 0 0 1 1 1 1 Microtubule binding DUF1843 PF08898.10 CBZ30020.1 - 3.9 8.0 7.2 11 6.6 0.1 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF1843) Dynein_heavy PF03028.15 CBZ30021.1 - 9.6e-05 22.5 0.0 0.0002 21.5 0.0 1.4 1 0 0 1 1 1 1 Dynein heavy chain region D6 P-loop domain WD40 PF00400.32 CBZ30021.1 - 0.0041 17.9 12.7 6.8 7.7 0.4 6.2 7 0 0 7 7 7 2 WD domain, G-beta repeat Frtz PF11768.8 CBZ30021.1 - 0.019 13.3 0.0 0.031 12.6 0.0 1.3 1 0 0 1 1 1 0 WD repeat-containing and planar cell polarity effector protein Fritz Acid_PPase PF12689.7 CBZ30022.1 - 3.1e-50 170.3 0.0 3.5e-50 170.1 0.0 1.0 1 0 0 1 1 1 1 Acid Phosphatase NIF PF03031.18 CBZ30022.1 - 0.032 14.0 0.0 0.2 11.4 0.0 2.0 1 1 0 1 1 1 0 NLI interacting factor-like phosphatase Hydrolase PF00702.26 CBZ30022.1 - 0.04 14.2 0.0 0.093 13.0 0.0 1.6 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase HAD PF12710.7 CBZ30022.1 - 0.18 12.2 0.0 0.41 11.0 0.0 1.6 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase Uso1_p115_C PF04871.13 CBZ30023.1 - 0.047 14.0 2.9 0.34 11.3 0.1 2.7 2 0 0 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region Tup_N PF08581.10 CBZ30023.1 - 0.11 12.8 4.8 0.31 11.4 0.2 2.4 2 0 0 2 2 2 0 Tup N-terminal FH2 PF02181.23 CBZ30023.1 - 0.64 9.1 4.0 8.4 5.4 1.3 2.2 2 0 0 2 2 2 0 Formin Homology 2 Domain FliO PF04347.13 CBZ30024.1 - 0.11 12.8 0.0 0.33 11.3 0.0 1.8 1 0 0 1 1 1 0 Flagellar biosynthesis protein, FliO DUF1279 PF06916.13 CBZ30027.1 - 0.073 13.6 0.2 0.073 13.6 0.2 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1279) FSA_C PF10479.9 CBZ30027.1 - 6.2 4.8 7.0 8.2 4.4 7.0 1.1 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus DUF1279 PF06916.13 CBZ30028.1 - 0.0029 18.1 0.1 0.0054 17.2 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1279) CFAP91 PF14738.6 CBZ30029.1 - 4.8e-45 153.3 3.0 4.8e-45 153.3 3.0 2.3 2 1 0 2 2 2 1 Cilia- and flagella-associated protein 91 RhlB PF12300.8 CBZ30030.1 - 0.29 11.3 3.6 0.54 10.4 3.6 1.4 1 0 0 1 1 1 0 ATP-dependent RNA helicase RhlB Baculo_IE-1 PF05290.11 CBZ30032.1 - 0.00051 20.0 1.7 0.00084 19.3 1.7 1.3 1 0 0 1 1 1 1 Baculovirus immediate-early protein (IE-0) zf-C3HC4_3 PF13920.6 CBZ30032.1 - 0.072 13.0 13.4 0.12 12.2 13.4 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Bac_small_YrzI PF09501.10 CBZ30032.1 - 0.35 11.0 2.1 1.2 9.3 2.1 1.8 1 1 0 1 1 1 0 Probable sporulation protein (Bac_small_yrzI) zf-RING_2 PF13639.6 CBZ30032.1 - 0.61 10.5 13.5 1 9.8 13.5 1.4 1 0 0 1 1 1 0 Ring finger domain Glyco_hydro_85 PF03644.13 CBZ30033.1 - 6.7e-85 285.1 0.0 1.2e-84 284.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 85 Peptidase_C97 PF05903.14 CBZ30033.1 - 7.1e-25 87.6 0.0 1.2e-24 86.9 0.0 1.3 1 0 0 1 1 1 1 PPPDE putative peptidase domain PUB PF09409.10 CBZ30033.1 - 3.5e-12 46.1 0.0 7.9e-12 44.9 0.0 1.6 1 0 0 1 1 1 1 PUB domain DUF3421 PF11901.8 CBZ30033.1 - 3.9e-07 30.1 0.4 0.0066 16.4 0.1 2.7 2 0 0 2 2 2 2 Protein of unknown function (DUF3421) FlxA PF14282.6 CBZ30034.1 - 0.013 15.5 2.1 0.013 15.5 2.1 5.7 1 1 10 11 11 11 0 FlxA-like protein Tup_N PF08581.10 CBZ30034.1 - 1.3 9.3 7.9 0.35 11.2 2.4 3.0 3 0 0 3 3 3 0 Tup N-terminal zf-MYND PF01753.18 CBZ30035.1 - 1.2e-07 31.7 10.9 1.2e-07 31.7 10.9 2.0 2 0 0 2 2 2 1 MYND finger Pkinase PF00069.25 CBZ30036.1 - 1.6e-54 185.0 0.0 2.5e-49 168.0 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ30036.1 - 7.5e-40 136.8 0.0 1.8e-37 129.1 0.0 2.6 2 0 0 2 2 2 2 Protein tyrosine kinase Kdo PF06293.14 CBZ30036.1 - 8e-05 22.1 0.0 0.00016 21.1 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 CBZ30036.1 - 0.00015 21.2 0.0 0.00053 19.4 0.0 1.7 1 1 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 CBZ30036.1 - 0.0032 16.3 0.0 0.0053 15.6 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase RIO1 PF01163.22 CBZ30036.1 - 0.011 15.4 0.0 0.02 14.5 0.0 1.4 1 0 0 1 1 1 0 RIO1 family APH PF01636.23 CBZ30036.1 - 0.044 13.7 0.3 6.4 6.6 0.0 2.5 1 1 1 2 2 2 0 Phosphotransferase enzyme family Epimerase PF01370.21 CBZ30037.1 - 5.5e-38 130.8 0.0 6.8e-38 130.5 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 CBZ30037.1 - 1.4e-32 113.4 0.0 1.4e-30 106.9 0.0 2.7 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 CBZ30037.1 - 1.9e-14 53.5 0.0 2.4e-13 49.9 0.0 2.1 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.19 CBZ30037.1 - 1.6e-09 37.2 0.0 1.3e-08 34.2 0.0 2.0 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 CBZ30037.1 - 1.5e-07 30.9 0.0 6.3e-07 28.8 0.0 1.9 1 1 0 1 1 1 1 Male sterility protein KR PF08659.10 CBZ30037.1 - 0.003 17.5 0.0 0.013 15.4 0.0 2.0 2 1 0 2 2 2 1 KR domain RmlD_sub_bind PF04321.17 CBZ30037.1 - 0.019 14.1 0.0 0.078 12.1 0.0 1.9 1 1 0 1 1 1 0 RmlD substrate binding domain DUF4232 PF14016.6 CBZ30037.1 - 0.1 12.8 0.0 0.19 11.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4232) DUF1800 PF08811.11 CBZ30037.1 - 0.27 10.2 0.0 0.4 9.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1800) CDC45 PF02724.14 CBZ30039.1 - 1.5e-85 287.8 0.0 1.8e-85 287.6 0.0 1.0 1 0 0 1 1 1 1 CDC45-like protein 2HCT PF03390.15 CBZ30039.1 - 0.037 12.6 0.7 0.065 11.8 0.7 1.3 1 0 0 1 1 1 0 2-hydroxycarboxylate transporter family Eapp_C PF10238.9 CBZ30039.1 - 0.12 12.4 0.3 0.35 10.9 0.3 1.7 1 0 0 1 1 1 0 E2F-associated phosphoprotein Nbs1_C PF08599.10 CBZ30039.1 - 0.44 10.7 4.2 1.4 9.1 0.5 2.8 2 0 0 2 2 2 0 DNA damage repair protein Nbs1 Spem1 PF15670.5 CBZ30039.1 - 4 6.9 5.6 9.6 5.7 5.6 1.6 1 0 0 1 1 1 0 Spermatid maturation protein 1 CoA_trans PF01144.23 CBZ30041.1 - 1.7e-95 318.5 1.1 2.3e-59 200.4 0.1 2.0 2 0 0 2 2 2 2 Coenzyme A transferase AcetylCoA_hyd_C PF13336.6 CBZ30041.1 - 0.0093 15.9 0.0 0.016 15.1 0.0 1.3 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase C-terminal domain RabGAP-TBC PF00566.18 CBZ30042.1 - 1.3e-06 28.2 0.4 2.1e-06 27.5 0.4 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Rhodanese PF00581.20 CBZ30042.1 - 0.011 16.3 0.0 0.028 14.9 0.0 1.7 1 0 0 1 1 1 0 Rhodanese-like domain NCA2 PF08637.10 CBZ30043.1 - 6e-36 124.1 0.0 1.3e-26 93.4 0.0 2.2 2 0 0 2 2 2 2 ATP synthase regulation protein NCA2 Gene66 PF02053.15 CBZ30043.1 - 0.05 13.2 0.2 8.4 6.0 0.0 2.4 2 0 0 2 2 2 0 Gene 66 (IR5) protein GRASP55_65 PF04495.14 CBZ30045.1 - 9.2e-46 155.6 0.0 3e-40 137.7 0.0 2.2 1 1 1 2 2 2 2 GRASP55/65 PDZ-like domain HSP90 PF00183.18 CBZ30046.1 - 2.7e-95 320.2 2.2 2e-93 314.1 0.3 2.0 1 1 1 2 2 2 2 Hsp90 protein HATPase_c_3 PF13589.6 CBZ30046.1 - 7.8e-11 42.0 0.0 1.8e-10 40.8 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 CBZ30046.1 - 1.2e-06 29.0 0.0 2.2e-06 28.1 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DPRP PF04244.13 CBZ30046.1 - 0.0083 16.0 0.1 0.015 15.2 0.1 1.3 1 0 0 1 1 1 1 Deoxyribodipyrimidine photo-lyase-related protein Ph1570 PF09638.10 CBZ30046.1 - 0.082 12.8 0.0 1.5 8.6 0.0 2.3 2 0 0 2 2 2 0 Ph1570 protein MMR_HSR1 PF01926.23 CBZ30047.1 - 1.1e-17 64.2 0.1 4.4e-13 49.3 0.0 2.4 2 0 0 2 2 2 2 50S ribosome-binding GTPase FeoB_N PF02421.18 CBZ30047.1 - 3e-11 43.1 0.3 3.6e-09 36.4 0.2 2.4 2 0 0 2 2 2 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 CBZ30047.1 - 9e-06 25.7 0.9 0.00014 21.8 0.3 2.6 2 1 0 2 2 2 1 RsgA GTPase GTP_EFTU PF00009.27 CBZ30047.1 - 9.2e-05 22.1 0.0 0.0018 17.8 0.0 2.6 2 1 0 3 3 3 1 Elongation factor Tu GTP binding domain Dynamin_N PF00350.23 CBZ30047.1 - 0.0024 18.0 0.3 0.02 15.0 0.2 2.5 2 1 0 2 2 2 1 Dynamin family AAA_18 PF13238.6 CBZ30047.1 - 0.0092 16.5 0.0 0.047 14.2 0.0 2.1 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 CBZ30047.1 - 0.032 14.6 0.0 2.5 8.5 0.0 2.8 3 0 0 3 3 3 0 RNA helicase MeaB PF03308.16 CBZ30047.1 - 0.04 12.9 0.1 0.1 11.5 0.1 1.7 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB DNA_circ_N PF07157.12 CBZ30047.1 - 0.079 13.4 0.0 0.22 12.0 0.0 1.7 1 0 0 1 1 1 0 DNA circularisation protein N-terminus AAA_16 PF13191.6 CBZ30047.1 - 0.11 12.9 0.9 0.8 10.1 0.0 2.7 2 1 0 2 2 2 0 AAA ATPase domain Roc PF08477.13 CBZ30047.1 - 0.24 11.6 0.8 13 6.0 0.1 2.9 2 1 2 4 4 4 0 Ras of Complex, Roc, domain of DAPkinase Diphthamide_syn PF01866.17 CBZ30048.1 - 5.2e-42 144.3 0.1 3.7e-23 82.4 0.0 3.1 3 0 0 3 3 3 2 Putative diphthamide synthesis protein zf-MYND PF01753.18 CBZ30049.1 - 4.4e-09 36.3 48.7 2.7e-05 24.2 17.5 3.1 3 0 0 3 3 3 2 MYND finger MOFRL PF05161.13 CBZ30049.1 - 0.46 10.7 4.3 2.8 8.2 0.2 3.1 2 1 0 2 2 2 0 MOFRL family RICH PF05062.12 CBZ30051.1 - 5.7 7.4 7.5 0.47 10.8 1.7 2.1 2 0 0 2 2 2 0 RICH domain zf-C3HC PF07967.13 CBZ30052.1 - 0.012 15.6 0.9 0.76 9.8 0.2 2.6 2 0 0 2 2 2 0 C3HC zinc finger-like NRDE-2 PF08424.10 CBZ30052.1 - 0.098 11.8 0.2 0.19 10.8 0.2 1.3 1 0 0 1 1 1 0 NRDE-2, necessary for RNA interference DUF2368 PF10166.9 CBZ30052.1 - 0.27 10.8 0.7 0.77 9.4 0.7 1.7 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2368) MAP65_ASE1 PF03999.12 CBZ30052.1 - 4.8 5.8 8.2 8.3 5.0 8.2 1.3 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) Tox-WTIP PF15654.6 CBZ30054.1 - 0.0057 17.0 0.1 0.02 15.3 0.0 1.9 2 0 0 2 2 2 1 Toxin with a conserved tryptophan and TIP tripeptide motif Bax1-I PF01027.20 CBZ30054.1 - 0.44 10.4 18.9 0.13 12.0 15.6 1.9 2 0 0 2 2 2 0 Inhibitor of apoptosis-promoting Bax1 KorB PF08535.10 CBZ30055.1 - 5.7e-05 23.1 0.0 0.00015 21.7 0.0 1.7 1 0 0 1 1 1 1 KorB domain DUF4455 PF14643.6 CBZ30055.1 - 0.0054 15.4 0.1 0.0075 15.0 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4455) Dpy19 PF10034.9 CBZ30055.1 - 0.15 10.2 0.0 0.22 9.7 0.0 1.1 1 0 0 1 1 1 0 Q-cell neuroblast polarisation Rad51 PF08423.11 CBZ30056.1 - 2e-33 115.8 0.1 5.4e-22 78.3 0.2 4.2 2 1 2 4 4 4 3 Rad51 AAA_25 PF13481.6 CBZ30056.1 - 4.2e-10 39.5 0.1 1.6e-09 37.6 0.0 1.9 2 0 0 2 2 2 1 AAA domain ATPase PF06745.13 CBZ30056.1 - 9.5e-05 21.9 0.2 0.00022 20.7 0.2 1.6 1 0 0 1 1 1 1 KaiC RecA PF00154.21 CBZ30056.1 - 0.00069 19.2 0.0 0.0013 18.3 0.0 1.3 1 0 0 1 1 1 1 recA bacterial DNA recombination protein AAA_16 PF13191.6 CBZ30056.1 - 0.039 14.3 0.1 0.13 12.7 0.0 2.0 2 0 0 2 2 2 0 AAA ATPase domain AAA PF00004.29 CBZ30056.1 - 0.17 12.3 0.0 0.49 10.8 0.0 1.8 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Radial_spoke PF04712.12 CBZ30057.1 - 6.2e-08 32.0 0.0 7.7e-07 28.4 0.0 2.3 2 1 1 3 3 3 1 Radial spokehead-like protein CAP_N PF01213.19 CBZ30058.1 - 0.25 10.8 2.2 13 5.2 0.2 2.2 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal UDPGP PF01704.18 CBZ30059.1 - 2.1e-24 85.9 0.0 4e-24 85.0 0.0 1.3 1 1 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase NTP_transf_3 PF12804.7 CBZ30059.1 - 0.042 14.2 0.2 0.14 12.5 0.2 1.9 1 0 0 1 1 1 0 MobA-like NTP transferase domain NUC173 PF08161.12 CBZ30060.1 - 1.2e-14 54.5 1.6 2e-12 47.2 0.2 3.4 3 0 0 3 3 3 2 NUC173 domain Peptidase_M32 PF02074.15 CBZ30061.1 - 9.3e-160 532.6 0.0 1.1e-159 532.4 0.0 1.0 1 0 0 1 1 1 1 Carboxypeptidase Taq (M32) metallopeptidase Iso_dh PF00180.20 CBZ30062.1 - 2e-106 356.1 0.0 2.4e-106 355.8 0.0 1.1 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase PdxA PF04166.12 CBZ30062.1 - 0.013 15.0 0.1 0.023 14.1 0.1 1.3 1 0 0 1 1 1 0 Pyridoxal phosphate biosynthetic protein PdxA Kinesin PF00225.23 CBZ30063.1 - 2.1e-102 342.5 0.0 3.6e-102 341.7 0.0 1.4 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 CBZ30063.1 - 2.6e-20 72.9 0.0 1.1e-19 70.9 0.0 1.9 2 0 0 2 2 2 1 Microtubule binding AAA_22 PF13401.6 CBZ30063.1 - 3.8e-05 24.0 0.6 0.049 13.9 0.0 3.7 3 0 0 3 3 3 1 AAA domain AAA_16 PF13191.6 CBZ30063.1 - 0.00021 21.7 0.4 0.1 13.0 0.0 3.8 3 1 0 3 3 3 1 AAA ATPase domain Ras PF00071.22 CBZ30063.1 - 0.003 17.2 0.0 0.89 9.1 0.0 2.9 3 0 0 3 3 3 1 Ras family RsgA_GTPase PF03193.16 CBZ30063.1 - 0.006 16.5 0.1 0.055 13.4 0.0 2.2 2 0 0 2 2 2 1 RsgA GTPase SmpA_OmlA PF04355.13 CBZ30063.1 - 0.0066 16.2 0.1 0.29 11.0 0.1 2.6 1 1 1 2 2 2 1 SmpA / OmlA family AAA_29 PF13555.6 CBZ30063.1 - 0.01 15.5 0.1 0.32 10.8 0.0 2.6 2 0 0 2 2 2 0 P-loop containing region of AAA domain Mito_fiss_reg PF05308.11 CBZ30063.1 - 0.014 15.5 0.1 0.16 12.0 0.0 2.5 2 0 0 2 2 2 0 Mitochondrial fission regulator CPT PF07931.12 CBZ30063.1 - 0.023 14.5 0.0 0.072 12.9 0.0 1.8 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein Mg_chelatase PF01078.21 CBZ30063.1 - 0.024 14.0 0.0 1.3 8.4 0.0 2.7 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI AAA_28 PF13521.6 CBZ30063.1 - 0.035 14.4 1.6 0.11 12.8 0.3 2.6 2 0 0 2 2 2 0 AAA domain Roc PF08477.13 CBZ30063.1 - 0.052 13.8 0.0 0.9 9.8 0.1 2.8 2 1 1 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase Kinesin_assoc PF16183.5 CBZ30063.1 - 0.075 13.2 0.5 0.31 11.2 0.5 2.1 1 1 0 1 1 1 0 Kinesin-associated FtsK_SpoIIIE PF01580.18 CBZ30063.1 - 0.082 12.2 0.8 0.68 9.2 0.0 2.9 3 0 0 3 3 3 0 FtsK/SpoIIIE family MMR_HSR1 PF01926.23 CBZ30063.1 - 0.087 12.9 0.9 3.9 7.6 0.2 2.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase ABC_tran PF00005.27 CBZ30063.1 - 0.14 12.7 0.3 0.67 10.5 0.1 2.2 2 0 0 2 2 2 0 ABC transporter RNA_helicase PF00910.22 CBZ30063.1 - 0.47 10.9 1.1 24 5.4 0.1 3.4 4 0 0 4 4 3 0 RNA helicase Peptidase_M17 PF00883.21 CBZ30064.1 - 1.3e-92 310.4 0.1 1.3e-92 310.4 0.1 1.5 2 0 0 2 2 2 1 Cytosol aminopeptidase family, catalytic domain Pdase_M17_N2 PF18295.1 CBZ30064.1 - 3.8e-29 101.4 2.7 7.8e-29 100.4 2.7 1.6 1 0 0 1 1 1 1 M17 aminopeptidase N-terminal domain 2 UPF0767 PF15990.5 CBZ30065.1 - 0.11 12.7 0.0 0.14 12.4 0.0 1.3 1 0 0 1 1 1 0 UPF0767 family 3HCDH_N PF02737.18 CBZ30068.1 - 2.4e-41 141.6 0.0 4.5e-41 140.7 0.0 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ECH_1 PF00378.20 CBZ30068.1 - 2.1e-29 102.6 0.0 3.8e-29 101.8 0.0 1.3 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase 3HCDH PF00725.22 CBZ30068.1 - 1.5e-17 63.9 0.1 2.5e-09 37.6 0.0 3.5 3 0 0 3 3 3 3 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain ECH_2 PF16113.5 CBZ30068.1 - 1.2e-14 54.6 0.0 2.2e-14 53.7 0.0 1.3 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase DAO PF01266.24 CBZ30068.1 - 0.0062 16.2 0.0 0.011 15.4 0.0 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 CBZ30068.1 - 0.015 14.5 0.0 0.035 13.3 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.20 CBZ30068.1 - 0.024 14.7 0.0 0.059 13.4 0.0 1.6 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase NAD_binding_9 PF13454.6 CBZ30068.1 - 0.024 14.6 0.0 0.06 13.3 0.0 1.7 1 0 0 1 1 1 0 FAD-NAD(P)-binding ApbA PF02558.16 CBZ30068.1 - 0.074 12.7 0.0 0.16 11.6 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA NAD_Gly3P_dh_N PF01210.23 CBZ30068.1 - 0.093 12.7 0.0 0.18 11.8 0.0 1.4 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Peptidase_M16_C PF05193.21 CBZ30069.1 - 4.7e-19 69.1 0.0 7.6e-19 68.4 0.0 1.3 1 0 0 1 1 1 1 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 CBZ30069.1 - 0.00058 19.9 0.0 0.0013 18.7 0.0 1.6 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) SRPRB PF09439.10 CBZ30070.1 - 1.3e-18 67.1 0.0 2.1e-18 66.4 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 CBZ30070.1 - 6.8e-05 22.9 0.0 0.00032 20.8 0.0 2.0 2 0 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 CBZ30070.1 - 0.00063 19.3 0.1 0.0022 17.6 0.1 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain DUF463 PF04317.12 CBZ30070.1 - 0.0028 16.6 0.1 0.4 9.6 0.0 2.4 2 0 0 2 2 2 2 YcjX-like family, DUF463 AAA_22 PF13401.6 CBZ30070.1 - 0.049 13.9 0.8 0.18 12.0 0.2 2.3 2 1 0 2 2 2 0 AAA domain AAA_33 PF13671.6 CBZ30070.1 - 0.07 13.3 0.1 0.2 11.8 0.0 1.9 2 0 0 2 2 2 0 AAA domain RsgA_GTPase PF03193.16 CBZ30070.1 - 0.087 12.7 0.1 0.39 10.6 0.0 2.0 2 0 0 2 2 2 0 RsgA GTPase AAA_16 PF13191.6 CBZ30070.1 - 0.095 13.1 2.6 0.64 10.4 0.3 2.9 2 1 0 2 2 2 0 AAA ATPase domain Lsm_C PF14894.6 CBZ30070.1 - 0.12 12.2 0.1 0.3 10.9 0.1 1.7 1 0 0 1 1 1 0 Lsm C-terminal Gtr1_RagA PF04670.12 CBZ30070.1 - 0.12 11.7 0.0 0.2 11.0 0.0 1.3 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region cobW PF02492.19 CBZ30070.1 - 0.13 11.8 0.0 0.32 10.6 0.0 1.7 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain IL32 PF15225.6 CBZ30070.1 - 0.18 12.2 0.7 1.6 9.1 0.1 2.7 2 1 1 3 3 3 0 Interleukin 32 LIM PF00412.22 CBZ30072.1 - 0.0002 21.5 0.3 0.00036 20.7 0.3 1.4 1 0 0 1 1 1 1 LIM domain zf-C4_ClpX PF06689.13 CBZ30072.1 - 0.1 12.5 0.1 0.4 10.6 0.0 2.0 2 0 0 2 2 2 0 ClpX C4-type zinc finger ThiF PF00899.21 CBZ30073.1 - 1.5e-07 31.1 0.1 4.1e-06 26.3 0.0 2.1 2 0 0 2 2 2 2 ThiF family PseudoU_synth_2 PF00849.22 CBZ30074.1 - 0.1 12.7 0.3 1 9.4 0.0 2.5 3 0 0 3 3 3 0 RNA pseudouridylate synthase eIF3g PF12353.8 CBZ30074.1 - 0.3 11.5 0.1 0.3 11.5 0.1 2.0 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit G Filament PF00038.21 CBZ30075.1 - 0.0005 19.8 9.4 0.0005 19.8 9.4 7.5 2 1 4 6 6 6 1 Intermediate filament protein Spc7 PF08317.11 CBZ30075.1 - 0.033 13.1 104.3 0.023 13.6 15.5 6.6 3 1 3 8 8 8 0 Spc7 kinetochore protein Lzipper-MIP1 PF14389.6 CBZ30075.1 - 0.19 12.1 0.0 0.19 12.1 0.0 10.4 6 3 4 10 10 10 0 Leucine-zipper of ternary complex factor MIP1 bZIP_1 PF00170.21 CBZ30075.1 - 0.2 11.8 0.0 0.2 11.8 0.0 8.2 9 0 0 9 9 9 0 bZIP transcription factor YqjK PF13997.6 CBZ30075.1 - 1.7 9.0 5.2 5.9 7.2 0.9 4.2 3 0 0 3 3 3 0 YqjK-like protein DnaJ PF00226.31 CBZ30077.1 - 2.2e-09 37.3 0.1 5.9e-09 35.9 0.1 1.7 1 0 0 1 1 1 1 DnaJ domain MCM PF00493.23 CBZ30078.1 - 5.8e-84 280.7 0.0 1.3e-83 279.5 0.0 1.5 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 CBZ30078.1 - 1.3e-26 92.9 0.0 2.6e-26 92.0 0.0 1.4 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 CBZ30078.1 - 7.8e-21 74.3 0.0 1.7e-20 73.2 0.0 1.6 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 CBZ30078.1 - 1.1e-08 35.6 0.0 4e-08 33.8 0.0 2.1 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 CBZ30078.1 - 2e-08 33.9 0.6 6.4e-07 29.0 0.0 2.7 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.26 CBZ30078.1 - 0.00032 20.4 0.0 0.002 17.9 0.0 2.1 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_3 PF07726.11 CBZ30078.1 - 0.0018 18.2 0.0 0.0041 17.0 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RPA_C PF08784.11 CBZ30078.1 - 0.0057 17.3 0.0 0.018 15.7 0.0 1.9 1 0 0 1 1 1 1 Replication protein A C terminal AAA_5 PF07728.14 CBZ30078.1 - 0.035 14.1 0.0 0.17 11.9 0.0 2.1 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA PF00004.29 CBZ30078.1 - 0.076 13.4 0.0 0.19 12.2 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) CcdA PF07362.12 CBZ30078.1 - 0.23 11.9 2.2 2.8 8.5 0.1 2.5 2 0 0 2 2 2 0 Post-segregation antitoxin CcdA Complex1_LYR PF05347.15 CBZ30079.1 - 9e-06 25.6 1.2 1.5e-05 24.9 1.2 1.5 1 0 0 1 1 1 1 Complex 1 protein (LYR family) ketoacyl-synt PF00109.26 CBZ30080.1 - 5.1e-38 131.1 0.7 1.5e-37 129.6 0.7 1.8 1 1 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 CBZ30080.1 - 5e-27 94.3 1.3 5.8e-27 94.0 0.3 1.7 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain FAM153 PF15722.5 CBZ30080.1 - 0.058 13.7 0.0 0.13 12.6 0.0 1.6 1 0 0 1 1 1 0 FAM153 family GTP_EFTU PF00009.27 CBZ30082.1 - 6.9e-35 120.4 0.0 2.1e-34 118.8 0.0 1.8 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain IF-2 PF11987.8 CBZ30082.1 - 1.2e-15 57.6 0.0 3e-15 56.2 0.0 1.7 1 0 0 1 1 1 1 Translation-initiation factor 2 GTP_EFTU_D2 PF03144.25 CBZ30082.1 - 2.1e-10 40.8 1.1 1.1e-07 32.1 0.0 3.3 3 0 0 3 3 3 1 Elongation factor Tu domain 2 GTP_EFTU_D4 PF14578.6 CBZ30082.1 - 1.4e-08 34.5 1.9 2.3e-08 33.8 0.7 2.0 2 0 0 2 2 2 1 Elongation factor Tu domain 4 MMR_HSR1 PF01926.23 CBZ30082.1 - 7.2e-08 32.5 0.1 5.4e-07 29.7 0.0 2.6 3 0 0 3 3 3 1 50S ribosome-binding GTPase Roc PF08477.13 CBZ30082.1 - 5.2e-05 23.4 0.0 0.00012 22.3 0.0 1.6 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase ATP_bind_1 PF03029.17 CBZ30082.1 - 0.0051 16.6 0.0 0.018 14.8 0.0 1.9 1 1 0 1 1 1 1 Conserved hypothetical ATP binding protein RsgA_GTPase PF03193.16 CBZ30082.1 - 0.0078 16.1 0.5 1.2 9.0 0.1 3.1 1 1 1 2 2 2 1 RsgA GTPase SRPRB PF09439.10 CBZ30082.1 - 0.02 14.3 0.0 0.069 12.6 0.0 2.0 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit Ras PF00071.22 CBZ30082.1 - 0.027 14.1 0.0 0.17 11.5 0.0 2.2 1 1 0 1 1 1 0 Ras family AAA_16 PF13191.6 CBZ30082.1 - 0.061 13.7 0.0 0.061 13.7 0.0 2.2 2 1 0 2 2 2 0 AAA ATPase domain Dynamin_N PF00350.23 CBZ30082.1 - 0.21 11.6 15.3 0.15 12.2 5.7 4.2 2 1 0 2 2 2 0 Dynamin family DUF4520 PF15016.6 CBZ30083.1 - 3.5e-21 75.1 0.1 3e-19 68.9 0.0 2.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4520) POLO_box PF00659.18 CBZ30083.1 - 0.014 15.6 0.0 0.096 12.9 0.0 2.2 2 0 0 2 2 2 0 POLO box duplicated region Corona_NS3b PF03053.14 CBZ30083.1 - 0.06 13.1 0.0 0.099 12.4 0.0 1.2 1 0 0 1 1 1 0 ORF3b coronavirus protein UQ_con PF00179.26 CBZ30085.1 - 6.5e-35 119.8 0.0 9.3e-35 119.3 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme FAM199X PF15814.5 CBZ30085.1 - 0.0001 21.5 0.8 0.00012 21.2 0.8 1.1 1 0 0 1 1 1 1 Protein family FAM199X BRE PF06113.12 CBZ30085.1 - 0.078 11.8 0.0 0.096 11.5 0.0 1.1 1 0 0 1 1 1 0 Brain and reproductive organ-expressed protein (BRE) Beach PF02138.18 CBZ30086.1 - 5e-96 321.3 0.0 1e-95 320.3 0.0 1.5 1 0 0 1 1 1 1 Beige/BEACH domain Laminin_G_3 PF13385.6 CBZ30086.1 - 1.1e-07 32.1 0.2 2.6e-07 30.9 0.2 1.6 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily GTP_EFTU PF00009.27 CBZ30087.1 - 3.5e-18 65.9 0.0 2.7e-17 63.0 0.0 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 CBZ30087.1 - 2e-05 24.8 0.5 7.4e-05 23.0 0.5 2.0 1 1 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 CBZ30087.1 - 4.1e-05 23.9 0.6 0.0001 22.6 0.6 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 CBZ30087.1 - 0.0072 16.4 0.0 0.06 13.4 0.0 2.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase PduV-EutP PF10662.9 CBZ30087.1 - 0.033 13.9 0.2 2.1 8.1 0.0 3.1 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation DUF2536 PF10750.9 CBZ30088.1 - 0.0089 15.9 0.0 0.014 15.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2536) TFIIS_C PF01096.18 CBZ30089.1 - 6e-15 54.8 7.1 1.1e-14 53.9 7.1 1.5 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS) PWWP PF00855.17 CBZ30089.1 - 2e-06 28.1 0.1 1.2e-05 25.6 0.0 2.2 2 0 0 2 2 2 1 PWWP domain UBD PF16455.5 CBZ30089.1 - 0.094 13.0 0.0 0.32 11.3 0.0 1.8 2 0 0 2 2 2 0 Ubiquitin-binding domain Med26 PF08711.11 CBZ30089.1 - 0.17 12.0 0.0 0.32 11.0 0.0 1.5 1 0 0 1 1 1 0 TFIIS helical bundle-like domain PWWP PF00855.17 CBZ30090.1 - 2.5e-11 43.8 1.3 4.5e-11 43.0 0.0 2.0 2 0 0 2 2 2 1 PWWP domain Med26 PF08711.11 CBZ30090.1 - 2.4e-06 27.5 0.0 5.5e-06 26.3 0.0 1.7 1 0 0 1 1 1 1 TFIIS helical bundle-like domain Zn_ribbon_SprT PF17283.2 CBZ30090.1 - 2e-05 24.4 0.9 6.5e-05 22.8 0.9 1.9 1 0 0 1 1 1 1 SprT-like zinc ribbon domain Lar_restr_allev PF14354.6 CBZ30090.1 - 0.00016 22.0 0.5 0.00042 20.7 0.5 1.8 1 0 0 1 1 1 1 Restriction alleviation protein Lar TFIIS_C PF01096.18 CBZ30090.1 - 0.014 15.2 0.7 0.034 14.0 0.7 1.7 1 0 0 1 1 1 0 Transcription factor S-II (TFIIS) Zn_Tnp_IS1595 PF12760.7 CBZ30090.1 - 0.031 14.3 1.1 0.031 14.3 1.1 2.1 2 0 0 2 2 2 0 Transposase zinc-ribbon domain zinc_ribbon_4 PF13717.6 CBZ30090.1 - 0.063 13.2 1.3 0.79 9.7 0.1 2.4 2 0 0 2 2 2 0 zinc-ribbon domain CHAP PF05257.16 CBZ30091.1 - 1.9e-17 63.6 0.1 3.1e-17 62.9 0.1 1.3 1 0 0 1 1 1 1 CHAP domain Fungus-induced PF10917.8 CBZ30092.1 - 0.41 11.0 5.6 0.47 10.8 0.5 4.0 2 0 0 2 2 2 0 Fungus-induced protein Y_phosphatase3 PF13350.6 CBZ30093.1 - 3.8e-55 187.4 0.1 4.2e-55 187.2 0.1 1.0 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase PF00102.27 CBZ30093.1 - 0.013 15.1 0.0 0.016 14.7 0.0 1.3 1 0 0 1 1 1 0 Protein-tyrosine phosphatase DSPc PF00782.20 CBZ30093.1 - 0.052 13.4 0.3 0.45 10.3 0.1 2.1 2 0 0 2 2 2 0 Dual specificity phosphatase, catalytic domain CHAP PF05257.16 CBZ30094.1 - 3.1e-15 56.5 0.0 5.9e-15 55.6 0.0 1.5 1 1 0 1 1 1 1 CHAP domain FeS PF04060.13 CBZ30094.1 - 0.17 11.6 0.3 0.39 10.4 0.3 1.6 1 0 0 1 1 1 0 Putative Fe-S cluster CHAP PF05257.16 CBZ30095.1 - 2e-05 25.1 0.1 0.0001 22.8 0.1 2.2 1 1 0 1 1 1 1 CHAP domain Kinesin PF00225.23 CBZ30098.1 - 0.0021 17.0 0.0 0.031 13.2 0.0 2.6 2 2 0 2 2 2 1 Kinesin motor domain DUF4670 PF15709.5 CBZ30098.1 - 1.3 8.3 16.7 2.6 7.3 16.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4670) Kinesin PF00225.23 CBZ30101.1 - 8.8e-07 28.2 0.1 0.14 11.0 0.0 4.6 5 1 0 5 5 5 2 Kinesin motor domain RRM_occluded PF16842.5 CBZ30101.1 - 0.053 13.4 0.0 0.54 10.2 0.0 2.5 2 0 0 2 2 2 0 Occluded RNA-recognition motif Sec8_exocyst PF04048.14 CBZ30101.1 - 0.13 12.2 0.2 1.1 9.1 0.0 2.6 3 0 0 3 3 3 0 Sec8 exocyst complex component specific domain DUF4835 PF16119.5 CBZ30105.1 - 0.17 11.0 0.1 0.32 10.1 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4835) Peptidase_S64 PF08192.11 CBZ30105.1 - 0.69 8.3 5.3 0.96 7.8 5.3 1.1 1 0 0 1 1 1 0 Peptidase family S64 Ribosomal_L18 PF17135.4 CBZ30106.1 - 0.11 11.8 0.0 0.31 10.4 0.0 1.7 1 0 0 1 1 1 0 Ribosomal protein 60S L18 and 50S L18e DUF1059 PF06348.11 CBZ30109.1 - 0.013 15.7 0.4 0.031 14.5 0.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1059) eIF-3_zeta PF05091.12 CBZ30110.1 - 7 5.5 16.5 17 4.2 16.5 1.7 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) ABC_tran PF00005.27 CBZ30113.1 - 4.4e-10 40.2 0.0 0.00057 20.4 0.0 2.7 2 0 0 2 2 2 2 ABC transporter SbcCD_C PF13558.6 CBZ30113.1 - 0.00013 22.1 0.7 0.0014 18.8 0.2 2.8 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_16 PF13191.6 CBZ30113.1 - 0.047 14.1 0.1 1 9.7 0.0 2.8 2 0 0 2 2 2 0 AAA ATPase domain AAA_22 PF13401.6 CBZ30113.1 - 0.052 13.8 0.0 0.24 11.7 0.0 2.2 2 0 0 2 2 2 0 AAA domain Tyr-DNA_phospho PF06087.12 CBZ30114.1 - 4.7e-67 226.7 0.0 6.6e-67 226.2 0.0 1.1 1 0 0 1 1 1 1 Tyrosyl-DNA phosphodiesterase HTH_IclR PF09339.10 CBZ30116.1 - 0.00036 20.3 0.1 21 5.0 0.0 4.0 4 0 0 4 4 4 3 IclR helix-turn-helix domain RBD-FIP PF09457.10 CBZ30116.1 - 0.0021 17.9 0.0 1e+02 2.9 0.0 4.6 4 0 0 4 4 4 0 FIP domain SH2_2 PF14633.6 CBZ30118.1 - 8.1e-21 74.4 0.1 1.5e-20 73.5 0.1 1.4 1 0 0 1 1 1 1 SH2 domain YqgF PF14639.6 CBZ30118.1 - 5.9e-12 45.6 0.0 5.6e-11 42.4 0.0 2.3 2 0 0 2 2 2 1 Holliday-junction resolvase-like of SPT6 Tex_YqgF PF16921.5 CBZ30118.1 - 0.00095 19.6 0.0 0.002 18.5 0.0 1.5 1 0 0 1 1 1 1 Tex protein YqgF-like domain HTH_5 PF01022.20 CBZ30118.1 - 0.063 13.2 0.1 0.2 11.6 0.1 1.8 1 0 0 1 1 1 0 Bacterial regulatory protein, arsR family HHH_7 PF14635.6 CBZ30118.1 - 0.18 12.2 0.0 0.43 11.0 0.0 1.6 1 0 0 1 1 1 0 Helix-hairpin-helix motif Trypsin_2 PF13365.6 CBZ30121.1 - 8.7e-06 26.7 0.0 1.6e-05 25.8 0.0 1.5 1 1 0 1 1 1 1 Trypsin-like peptidase domain Trypsin PF00089.26 CBZ30121.1 - 0.013 15.3 0.2 0.036 13.9 0.2 1.8 1 1 0 1 1 1 0 Trypsin VPS9 PF02204.18 CBZ30122.1 - 0.039 14.2 0.0 0.18 12.0 0.0 2.1 1 0 0 1 1 1 0 Vacuolar sorting protein 9 (VPS9) domain Ribosomal_S13_N PF08069.12 CBZ30123.1 - 4.4e-24 84.3 1.5 8.6e-24 83.4 1.5 1.5 1 0 0 1 1 1 1 Ribosomal S13/S15 N-terminal domain Ribosomal_S15 PF00312.22 CBZ30123.1 - 1.9e-13 50.4 1.1 3.2e-13 49.7 1.1 1.3 1 0 0 1 1 1 1 Ribosomal protein S15 DUF3958 PF13125.6 CBZ30124.1 - 0.011 15.9 2.6 0.17 12.1 0.1 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3958) AAA_13 PF13166.6 CBZ30125.1 - 0.024 13.3 0.7 3.3 6.2 0.0 2.1 2 0 0 2 2 2 0 AAA domain kleA_kleC PF17383.2 CBZ30125.1 - 5.1 7.5 5.8 0.95 9.8 0.4 2.6 2 2 0 2 2 2 0 Uncharacterized KorC regulated protein A Lebercilin PF15619.6 CBZ30125.1 - 5.4 6.6 9.3 6.5 6.4 1.3 2.3 2 0 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease DUF4381 PF14316.6 CBZ30126.1 - 4e-05 23.9 0.6 0.45 10.7 0.1 2.6 2 0 0 2 2 2 2 Domain of unknown function (DUF4381) EphA2_TM PF14575.6 CBZ30126.1 - 5.5e-05 24.0 14.8 4.6 8.2 1.8 6.9 3 2 1 4 4 3 2 Ephrin type-A receptor 2 transmembrane domain Amnionless PF14828.6 CBZ30126.1 - 0.0015 17.5 0.0 0.57 9.0 0.0 2.4 2 0 0 2 2 2 2 Amnionless CoA_binding_3 PF13727.6 CBZ30126.1 - 0.0049 16.9 3.0 2 8.4 0.2 2.5 2 0 0 2 2 2 2 CoA-binding domain DUF1206 PF06724.11 CBZ30126.1 - 0.046 13.8 1.9 19 5.4 0.0 3.9 3 0 0 3 3 2 0 Domain of Unknown Function (DUF1206) DUF5367 PF17329.2 CBZ30126.1 - 0.088 12.9 0.0 25 5.1 0.0 2.4 2 0 0 2 2 2 0 Family of unknown function (DUF5367) DUF1600 PF07667.11 CBZ30126.1 - 0.12 12.6 0.2 21 5.4 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1600) Robl_LC7 PF03259.17 CBZ30126.1 - 0.16 11.8 4.2 9.1 6.1 0.3 2.8 2 0 0 2 2 2 0 Roadblock/LC7 domain PepSY_TM PF03929.16 CBZ30126.1 - 0.18 11.5 0.1 0.16 11.6 0.2 6.0 2 1 3 5 5 4 0 PepSY-associated TM region Cytochrome-c551 PF10643.9 CBZ30126.1 - 0.22 11.1 0.6 27 4.3 0.0 2.8 2 2 0 2 2 2 0 Photosystem P840 reaction-centre cytochrome c-551 SRP9-21 PF05486.12 CBZ30126.1 - 0.31 11.4 7.4 21 5.6 0.1 3.8 3 0 0 3 3 3 0 Signal recognition particle 9 kDa protein (SRP9) HlyIII PF03006.20 CBZ30126.1 - 0.67 9.6 8.5 7.1 6.3 0.1 3.2 3 0 0 3 3 3 0 Haemolysin-III related Holin_BhlA PF10960.8 CBZ30126.1 - 1.1 9.2 4.8 27 4.8 0.4 2.9 2 2 0 2 2 2 0 BhlA holin family HIG_1_N PF04588.13 CBZ30126.1 - 2.3 8.5 5.6 41 4.5 0.1 3.3 3 0 0 3 3 3 0 Hypoxia induced protein conserved region LSM PF01423.22 CBZ30127.1 - 6.8e-14 51.3 0.1 9.5e-14 50.8 0.1 1.2 1 0 0 1 1 1 1 LSM domain Zip PF02535.22 CBZ30128.1 - 1.8e-36 126.0 18.1 4.1e-25 88.7 9.7 2.0 1 1 1 2 2 2 2 ZIP Zinc transporter Sdh_cyt PF01127.22 CBZ30128.1 - 0.006 16.6 9.0 0.05 13.6 0.0 3.7 2 1 0 3 3 3 2 Succinate dehydrogenase/Fumarate reductase transmembrane subunit NiFe_hyd_3_EhaA PF17367.2 CBZ30128.1 - 0.4 10.8 0.1 0.4 10.8 0.1 3.1 2 1 1 4 4 4 0 NiFe-hydrogenase-type-3 Eha complex subunit A Coatomer_WDAD PF04053.14 CBZ30129.1 - 8.5e-137 456.8 0.0 1.4e-136 456.1 0.0 1.4 1 0 0 1 1 1 1 Coatomer WD associated region WD40 PF00400.32 CBZ30129.1 - 2.6e-27 94.5 1.6 3.1e-07 31.0 0.0 6.5 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBZ30129.1 - 7.6e-08 32.6 0.0 2.5 8.5 0.0 5.6 4 3 1 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain TPR_8 PF13181.6 CBZ30129.1 - 0.019 15.1 0.2 0.18 12.1 0.0 2.6 2 1 1 3 3 3 0 Tetratricopeptide repeat Clathrin PF00637.20 CBZ30129.1 - 0.15 11.9 0.2 2.3 8.1 0.0 2.5 1 1 0 2 2 2 0 Region in Clathrin and VPS TPR_12 PF13424.6 CBZ30129.1 - 0.39 11.1 2.2 11 6.3 0.1 3.1 1 1 3 4 4 4 0 Tetratricopeptide repeat EF-hand_7 PF13499.6 CBZ30130.1 - 2.7e-06 27.7 0.1 8.1e-05 23.0 0.1 3.0 2 1 1 3 3 3 1 EF-hand domain pair EF-hand_6 PF13405.6 CBZ30130.1 - 0.00014 21.5 0.0 0.0058 16.5 0.0 2.8 2 0 0 2 2 2 1 EF-hand domain EF-hand_5 PF13202.6 CBZ30130.1 - 0.00017 20.9 0.0 0.00043 19.7 0.0 1.7 1 0 0 1 1 1 1 EF hand EF-hand_1 PF00036.32 CBZ30130.1 - 0.0028 17.1 0.0 0.04 13.5 0.0 2.7 2 0 0 2 2 2 1 EF hand DUF2959 PF11172.8 CBZ30130.1 - 0.027 14.6 0.2 0.096 12.8 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2959) EF-hand_13 PF17958.1 CBZ30130.1 - 0.076 12.8 0.0 1.7 8.5 0.0 2.9 3 0 0 3 3 3 0 EF-hand domain Ribosomal_L44 PF00935.19 CBZ30131.1 - 1.2e-31 109.0 9.1 1.7e-31 108.5 9.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L44 NrsF PF06532.11 CBZ30132.1 - 0.42 10.3 5.4 0.58 9.8 5.4 1.2 1 0 0 1 1 1 0 Negative regulator of sigma F Miga PF10265.9 CBZ30133.1 - 5.6 5.8 23.6 7.2 5.5 23.6 1.1 1 0 0 1 1 1 0 Mitoguardin Glyco_hydro_44 PF12891.7 CBZ30133.1 - 6.7 6.6 7.9 4.2 7.2 3.0 2.2 1 1 1 2 2 2 0 Glycoside hydrolase family 44 ABC_tran PF00005.27 CBZ30134.1 - 4.5e-19 69.3 0.0 7.8e-19 68.5 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_16 PF13191.6 CBZ30134.1 - 0.0066 16.8 0.1 0.027 14.9 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain AAA_29 PF13555.6 CBZ30134.1 - 0.01 15.6 0.0 0.025 14.3 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_25 PF13481.6 CBZ30134.1 - 0.052 13.1 0.0 0.24 11.0 0.0 2.0 2 0 0 2 2 2 0 AAA domain SMC_N PF02463.19 CBZ30134.1 - 0.11 11.9 0.0 2 7.8 0.0 1.9 1 1 0 2 2 2 0 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 CBZ30134.1 - 0.17 12.0 0.1 0.55 10.3 0.1 1.9 1 0 0 1 1 1 0 50S ribosome-binding GTPase FA_desaturase PF00487.24 CBZ30135.1 - 8.7e-25 88.0 29.9 8.7e-25 88.0 29.9 1.5 1 1 0 1 1 1 1 Fatty acid desaturase adh_short PF00106.25 CBZ30136.1 - 8.3e-36 123.3 0.1 1.1e-35 122.9 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CBZ30136.1 - 2.6e-22 79.5 0.0 3.6e-22 79.1 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Exog_C PF18026.1 CBZ30136.1 - 0.00042 20.3 0.1 0.001 19.1 0.1 1.6 1 0 0 1 1 1 1 Endo/exonuclease (EXOG) C-terminal domain KR PF08659.10 CBZ30136.1 - 0.00046 20.1 0.0 0.00077 19.4 0.0 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_2 PF03446.15 CBZ30136.1 - 0.0092 16.2 0.2 0.021 15.0 0.0 1.7 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase Sacchrp_dh_NADP PF03435.18 CBZ30136.1 - 0.026 14.8 0.1 0.043 14.1 0.1 1.5 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Epimerase PF01370.21 CBZ30136.1 - 0.058 12.8 0.0 0.086 12.3 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family LRR_4 PF12799.7 CBZ30137.1 - 8.6e-08 32.4 8.8 0.15 12.6 1.7 6.1 3 1 7 10 10 10 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CBZ30137.1 - 0.00034 20.3 6.3 0.098 12.4 0.0 5.2 2 1 6 8 8 8 3 Leucine rich repeat LRR_6 PF13516.6 CBZ30137.1 - 0.0049 16.8 12.2 11 6.4 0.0 7.1 7 0 0 7 7 7 1 Leucine Rich repeat LRR_5 PF13306.6 CBZ30137.1 - 0.088 12.8 0.0 0.28 11.2 0.0 1.8 1 0 0 1 1 1 0 BspA type Leucine rich repeat region (6 copies) LRR_1 PF00560.33 CBZ30137.1 - 6.6 7.7 10.6 96 4.2 2.3 5.6 4 2 0 4 4 4 0 Leucine Rich Repeat Pkinase PF00069.25 CBZ30138.1 - 8e-40 136.9 0.0 9.9e-40 136.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ30138.1 - 3.2e-23 82.4 0.0 3.7e-23 82.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CBZ30138.1 - 2.4e-06 27.1 0.0 1.3e-05 24.7 0.0 1.9 2 0 0 2 2 2 1 Kinase-like Seadorna_VP7 PF07387.11 CBZ30138.1 - 0.26 10.3 0.0 0.38 9.8 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 DnaJ PF00226.31 CBZ30139.1 - 4.8e-13 49.0 0.0 9.7e-13 48.0 0.0 1.5 1 0 0 1 1 1 1 DnaJ domain Wzy_C_2 PF11846.8 CBZ30139.1 - 0.99 9.3 10.0 0.23 11.4 1.3 2.8 3 0 0 3 3 3 0 Virulence factor membrane-bound polymerase, C-terminal CLPTM1 PF05602.12 CBZ30140.1 - 3e-99 333.0 0.1 3.7e-99 332.6 0.1 1.1 1 0 0 1 1 1 1 Cleft lip and palate transmembrane protein 1 (CLPTM1) PQ-loop PF04193.14 CBZ30140.1 - 0.029 14.1 0.3 0.13 12.0 0.3 2.1 1 0 0 1 1 1 0 PQ loop repeat EcoEI_R_C PF08463.10 CBZ30141.1 - 0.2 11.8 0.0 0.39 10.8 0.0 1.4 1 0 0 1 1 1 0 EcoEI R protein C-terminal Reticulon PF02453.17 CBZ30141.1 - 3 7.8 7.9 12 5.8 7.9 2.0 1 1 0 1 1 1 0 Reticulon peroxidase PF00141.23 CBZ30142.1 - 4.8e-45 154.0 0.0 7.7e-45 153.3 0.0 1.3 1 1 0 1 1 1 1 Peroxidase G6PD_C PF02781.16 CBZ30143.1 - 2.2e-108 361.8 0.0 3e-108 361.4 0.0 1.2 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, C-terminal domain G6PD_N PF00479.22 CBZ30143.1 - 4.1e-58 196.9 0.0 7.4e-58 196.1 0.0 1.4 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, NAD binding domain HPP PF04982.13 CBZ30144.1 - 2.7e-05 24.4 2.2 2.8e-05 24.3 2.2 1.0 1 0 0 1 1 1 1 HPP family ADK PF00406.22 CBZ30147.1 - 6.8e-52 175.6 0.0 8.2e-52 175.3 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 CBZ30147.1 - 1.1e-22 80.9 0.0 1.8e-22 80.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain ADK_lid PF05191.14 CBZ30147.1 - 1e-15 57.4 0.1 2.3e-15 56.3 0.1 1.6 1 0 0 1 1 1 1 Adenylate kinase, active site lid AAA_18 PF13238.6 CBZ30147.1 - 0.0045 17.5 0.4 0.015 15.9 0.0 2.1 2 2 1 3 3 3 1 AAA domain AAA_33 PF13671.6 CBZ30147.1 - 0.015 15.5 0.0 0.04 14.1 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_28 PF13521.6 CBZ30147.1 - 0.028 14.6 0.1 0.18 12.0 0.0 2.0 2 0 0 2 2 2 0 AAA domain Hydin_ADK PF17213.3 CBZ30147.1 - 0.075 13.3 0.0 0.44 10.8 0.0 2.0 1 1 1 2 2 2 0 Hydin Adenylate kinase-like domain ADK PF00406.22 CBZ30148.1 - 5.2e-27 94.8 0.0 6.8e-27 94.4 0.0 1.0 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 CBZ30148.1 - 3.7e-13 50.1 0.0 1.1e-12 48.6 0.0 1.6 2 0 0 2 2 2 1 AAA domain ADK_lid PF05191.14 CBZ30148.1 - 1.4e-12 47.4 0.0 2.7e-12 46.5 0.0 1.5 1 0 0 1 1 1 1 Adenylate kinase, active site lid Hydin_ADK PF17213.3 CBZ30148.1 - 2.4e-05 24.7 0.1 0.018 15.3 0.0 2.4 2 0 0 2 2 2 2 Hydin Adenylate kinase-like domain AAA_18 PF13238.6 CBZ30148.1 - 0.00019 22.0 0.0 0.00042 20.9 0.0 1.6 1 1 0 1 1 1 1 AAA domain MscS_porin PF12795.7 CBZ30148.1 - 0.0037 16.8 0.1 0.0068 16.0 0.1 1.4 1 0 0 1 1 1 1 Mechanosensitive ion channel porin domain AAA_33 PF13671.6 CBZ30148.1 - 0.0051 17.0 0.0 0.012 15.7 0.0 1.6 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.6 CBZ30148.1 - 0.013 15.8 0.0 0.03 14.6 0.0 1.6 2 0 0 2 2 2 0 AAA domain RuvB_N PF05496.12 CBZ30148.1 - 0.094 12.5 0.0 0.33 10.7 0.0 1.9 1 1 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain Cytidylate_kin PF02224.18 CBZ30148.1 - 0.16 11.7 0.3 0.26 11.0 0.0 1.5 2 0 0 2 2 2 0 Cytidylate kinase Ldh_1_C PF02866.18 CBZ30149.1 - 2e-15 57.1 0.0 3.2e-07 30.4 0.0 2.1 2 0 0 2 2 2 2 lactate/malate dehydrogenase, alpha/beta C-terminal domain Ldh_1_N PF00056.23 CBZ30149.1 - 3.2e-12 46.7 0.0 5.3e-12 46.0 0.0 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain THF_DHG_CYH_C PF02882.19 CBZ30149.1 - 0.058 12.7 0.1 0.25 10.6 0.0 2.0 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Semialdhyde_dh PF01118.24 CBZ30149.1 - 0.077 13.4 0.0 0.21 12.0 0.0 1.8 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Ldh_1_C PF02866.18 CBZ30150.1 - 1.1e-46 158.8 0.0 2e-46 157.9 0.0 1.4 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Ldh_1_N PF00056.23 CBZ30150.1 - 1.5e-44 151.5 0.0 2e-44 151.1 0.0 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Semialdhyde_dh PF01118.24 CBZ30150.1 - 0.00085 19.8 0.0 0.0023 18.4 0.0 1.8 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain 3Beta_HSD PF01073.19 CBZ30150.1 - 0.0015 17.6 0.0 0.0026 16.8 0.0 1.4 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family DapB_N PF01113.20 CBZ30150.1 - 0.037 14.2 0.0 0.08 13.1 0.0 1.5 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus THF_DHG_CYH_C PF02882.19 CBZ30150.1 - 0.052 12.9 0.0 0.36 10.2 0.0 2.1 1 1 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Ldh_1_N PF00056.23 CBZ30151.1 - 2.1e-36 125.1 0.0 2.8e-36 124.7 0.0 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.18 CBZ30151.1 - 2.8e-36 124.9 0.0 4.8e-36 124.2 0.0 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain 3Beta_HSD PF01073.19 CBZ30151.1 - 0.00011 21.4 0.0 0.00015 20.9 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Semialdhyde_dh PF01118.24 CBZ30151.1 - 0.0014 19.0 0.0 0.0027 18.1 0.0 1.5 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain THF_DHG_CYH_C PF02882.19 CBZ30151.1 - 0.066 12.5 0.0 0.45 9.8 0.0 2.2 1 1 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Ldh_1_C PF02866.18 CBZ30152.1 - 1.3e-41 142.3 0.0 1.9e-41 141.8 0.0 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Ldh_1_N PF00056.23 CBZ30152.1 - 4.8e-41 140.1 0.0 6.5e-41 139.7 0.0 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain 3Beta_HSD PF01073.19 CBZ30152.1 - 0.029 13.4 0.0 0.043 12.8 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family DUF3756 PF12581.8 CBZ30152.1 - 0.3 11.0 1.5 1.8 8.5 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3756) Nop25 PF09805.9 CBZ30153.1 - 1e-07 32.5 12.3 1e-07 32.5 12.3 2.7 3 1 0 3 3 3 1 Nucleolar protein 12 (25kDa) Methyltransf_25 PF13649.6 CBZ30155.1 - 0.0067 17.1 0.1 0.042 14.5 0.1 2.3 2 0 0 2 2 2 1 Methyltransferase domain DUF1935 PF09149.10 CBZ30156.1 - 1.6e-118 388.2 4.3 2.4e-30 104.9 0.1 4.0 4 0 0 4 4 4 4 Domain of unknown function (DUF1935) OCRE PF17780.1 CBZ30156.1 - 0.14 12.2 4.9 3.2 7.9 0.0 3.8 4 0 0 4 4 4 0 OCRE domain DUF1935 PF09149.10 CBZ30157.1 - 6.7e-117 383.0 0.1 3.2e-30 104.5 0.0 4.1 4 0 0 4 4 4 4 Domain of unknown function (DUF1935) CS PF04969.16 CBZ30158.1 - 8.1e-08 33.2 0.0 1.2e-07 32.6 0.0 1.3 1 0 0 1 1 1 1 CS domain EMP24_GP25L PF01105.24 CBZ30159.1 - 2.7e-10 40.5 0.1 5.9e-10 39.4 0.1 1.7 1 1 0 1 1 1 1 emp24/gp25L/p24 family/GOLD MCU PF04678.13 CBZ30159.1 - 0.072 13.2 0.9 0.16 12.0 0.9 1.8 1 1 0 1 1 1 0 Mitochondrial calcium uniporter DUF3568 PF12092.8 CBZ30159.1 - 0.08 13.0 0.1 0.28 11.3 0.1 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3568) IFT81_CH PF18383.1 CBZ30160.1 - 2e-30 105.5 0.2 6.4e-30 103.9 0.2 1.9 1 0 0 1 1 1 1 Intraflagellar transport 81 calponin homology domain Spc7 PF08317.11 CBZ30160.1 - 0.00094 18.2 7.8 0.00094 18.2 7.8 4.3 2 1 1 4 4 4 3 Spc7 kinetochore protein Cep57_MT_bd PF06657.13 CBZ30160.1 - 0.061 13.8 0.1 0.061 13.8 0.1 5.7 4 2 3 7 7 7 0 Centrosome microtubule-binding domain of Cep57 DUF465 PF04325.13 CBZ30160.1 - 0.076 13.1 3.1 0.14 12.3 0.2 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF465) Baculo_PEP_C PF04513.12 CBZ30160.1 - 0.11 12.6 19.0 0.57 10.2 2.3 5.4 2 1 4 6 6 6 0 Baculovirus polyhedron envelope protein, PEP, C terminus IZUMO PF15005.6 CBZ30160.1 - 3.8 8.0 22.0 1.1 9.7 0.1 5.3 2 2 2 5 5 5 0 Izumo sperm-egg fusion, Ig domain-associated RIIa PF02197.17 CBZ30163.1 - 1.4e-06 27.8 0.5 2e-06 27.3 0.5 1.3 1 0 0 1 1 1 1 Regulatory subunit of type II PKA R-subunit Dpy-30 PF05186.13 CBZ30163.1 - 0.00012 21.7 0.1 0.00025 20.7 0.1 1.6 1 1 0 1 1 1 1 Dpy-30 motif Endotoxin_C2 PF18449.1 CBZ30163.1 - 0.0086 16.4 0.2 0.014 15.7 0.2 1.3 1 0 0 1 1 1 1 Delta endotoxin Sigma70_r2 PF04542.14 CBZ30163.1 - 0.023 14.5 0.0 0.035 13.9 0.0 1.3 1 0 0 1 1 1 0 Sigma-70 region 2 MHB PF16525.5 CBZ30163.1 - 0.034 14.4 1.0 0.29 11.4 0.2 2.2 1 1 1 2 2 2 0 Haemophore, haem-binding Pyr_redox_2 PF07992.14 CBZ30164.1 - 4.1e-09 36.1 0.0 5.3e-07 29.1 0.0 2.4 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 CBZ30164.1 - 0.00042 20.5 0.1 0.0011 19.1 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 CBZ30164.1 - 0.0024 17.1 0.1 0.0045 16.2 0.1 1.4 1 0 0 1 1 1 1 Thi4 family DAO PF01266.24 CBZ30164.1 - 0.0035 17.0 4.3 0.39 10.2 0.7 2.4 1 1 1 2 2 2 2 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 CBZ30164.1 - 0.0084 15.2 0.3 0.017 14.2 0.3 1.5 1 0 0 1 1 1 1 Lycopene cyclase protein Trp_halogenase PF04820.14 CBZ30164.1 - 0.045 12.6 0.3 0.07 12.0 0.3 1.2 1 0 0 1 1 1 0 Tryptophan halogenase ThiF PF00899.21 CBZ30164.1 - 0.064 12.6 0.1 0.12 11.7 0.1 1.4 1 0 0 1 1 1 0 ThiF family HI0933_like PF03486.14 CBZ30164.1 - 0.089 11.5 1.0 0.89 8.2 0.4 2.2 2 0 0 2 2 2 0 HI0933-like protein TrkA_N PF02254.18 CBZ30164.1 - 0.1 12.9 0.3 0.28 11.5 0.3 1.8 1 1 0 1 1 1 0 TrkA-N domain LapA_dom PF06305.11 CBZ30164.1 - 0.2 11.5 1.1 0.46 10.3 0.4 1.9 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain NAD_binding_9 PF13454.6 CBZ30164.1 - 0.24 11.4 2.8 0.54 10.2 0.1 2.7 3 0 0 3 3 3 0 FAD-NAD(P)-binding FAD_binding_2 PF00890.24 CBZ30164.1 - 0.34 10.0 2.5 0.49 9.4 1.2 1.9 1 1 0 1 1 1 0 FAD binding domain Peptidase_C2 PF00648.21 CBZ30165.1 - 2.2e-06 26.9 0.0 3.9e-06 26.1 0.0 1.3 1 0 0 1 1 1 1 Calpain family cysteine protease Mon1 PF03164.14 CBZ30166.1 - 1.5e-32 113.2 0.0 1e-12 47.8 0.0 3.0 3 0 0 3 3 3 3 Trafficking protein Mon1 WD40 PF00400.32 CBZ30167.1 - 7.1e-15 55.1 7.1 0.0047 17.7 0.0 7.3 7 1 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBZ30167.1 - 0.029 14.7 0.0 6.5 7.1 0.0 3.7 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain PseudoU_synth_1 PF01416.20 CBZ30168.1 - 9.1e-12 45.4 0.1 4.1e-08 33.6 0.1 3.3 2 1 0 2 2 2 2 tRNA pseudouridine synthase Synaphin PF05835.12 CBZ30168.1 - 1 9.6 8.7 3 8.1 0.2 3.1 3 0 0 3 3 3 0 Synaphin protein START PF01852.19 CBZ30169.1 - 0.0097 15.3 0.1 0.016 14.7 0.1 1.2 1 0 0 1 1 1 1 START domain DS PF01916.17 CBZ30170.1 - 3.2e-52 177.6 0.0 2.5e-36 125.4 0.0 4.2 4 0 0 4 4 4 4 Deoxyhypusine synthase AAA PF00004.29 CBZ30171.1 - 1.2e-09 38.7 0.0 3.4e-07 30.7 0.0 2.4 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 CBZ30171.1 - 2e-06 27.9 0.1 5.8e-06 26.4 0.0 1.8 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 CBZ30171.1 - 4.8e-05 23.8 0.4 0.00045 20.6 0.4 2.5 1 1 0 1 1 1 1 AAA ATPase domain AAA_6 PF12774.7 CBZ30171.1 - 0.0024 16.9 0.0 0.0037 16.3 0.0 1.2 1 0 0 1 1 1 1 Hydrolytic ATP binding site of dynein motor region AAA_18 PF13238.6 CBZ30171.1 - 0.0029 18.1 0.0 0.0063 17.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.6 CBZ30171.1 - 0.0041 17.4 0.0 0.0096 16.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain DUF815 PF05673.13 CBZ30171.1 - 0.0065 15.7 0.0 0.011 14.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_7 PF12775.7 CBZ30171.1 - 0.0077 15.8 0.0 0.014 14.9 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region RNA_helicase PF00910.22 CBZ30171.1 - 0.01 16.2 0.0 0.03 14.7 0.0 1.7 2 0 0 2 2 1 0 RNA helicase AAA_17 PF13207.6 CBZ30171.1 - 0.012 16.0 0.0 0.025 15.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 CBZ30171.1 - 0.017 15.3 0.0 0.048 13.8 0.0 1.7 2 0 0 2 2 1 0 AAA domain AAA_24 PF13479.6 CBZ30171.1 - 0.032 14.0 0.0 0.094 12.4 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.6 CBZ30171.1 - 0.032 14.6 0.0 0.081 13.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 CBZ30171.1 - 0.043 13.8 0.0 0.078 13.0 0.0 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_22 PF13401.6 CBZ30171.1 - 0.055 13.7 0.0 0.11 12.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 CBZ30171.1 - 0.11 12.4 0.0 0.3 11.0 0.0 1.7 1 0 0 1 1 1 0 NACHT domain KAP_NTPase PF07693.14 CBZ30171.1 - 0.11 11.7 0.0 0.17 11.1 0.0 1.2 1 0 0 1 1 1 0 KAP family P-loop domain AAA_2 PF07724.14 CBZ30171.1 - 0.16 12.1 0.0 0.26 11.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) RuvB_N PF05496.12 CBZ30171.1 - 0.17 11.6 0.0 0.3 10.8 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain eIF-5_eIF-2B PF01873.17 CBZ30172.1 - 2.4e-33 114.5 0.0 4.5e-33 113.6 0.0 1.4 1 0 0 1 1 1 1 Domain found in IF2B/IF5 W2 PF02020.18 CBZ30172.1 - 0.0012 18.9 0.1 0.0045 17.1 0.1 2.0 1 0 0 1 1 1 1 eIF4-gamma/eIF5/eIF2-epsilon RNA_pol_Rpb1_5 PF04998.17 CBZ30173.1 - 5.7e-76 255.5 0.0 8.2e-76 254.9 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.20 CBZ30173.1 - 3.5e-67 225.8 0.0 6.2e-67 225.0 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_1 PF04997.12 CBZ30173.1 - 2.9e-53 181.3 0.0 4.5e-53 180.6 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_3 PF04983.18 CBZ30173.1 - 3.2e-31 108.4 0.0 8.1e-31 107.1 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.17 CBZ30173.1 - 1.1e-30 105.8 0.0 2.8e-30 104.4 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 Rpr2 PF04032.16 CBZ30173.1 - 2.1 8.7 6.4 0.71 10.2 1.8 2.5 2 0 0 2 2 2 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain COG6 PF06419.11 CBZ30174.1 - 1.4e-46 159.0 0.1 1e-43 149.6 0.0 3.0 3 0 0 3 3 3 2 Conserved oligomeric complex COG6 Occludin_ELL PF07303.13 CBZ30174.1 - 0.0031 18.2 2.9 0.0043 17.8 1.3 2.1 1 1 1 2 2 2 1 Occludin homology domain DASH_Dad3 PF08656.10 CBZ30174.1 - 0.11 12.6 0.1 7.3 6.8 0.1 2.8 2 0 0 2 2 2 0 DASH complex subunit Dad3 DUF4766 PF15973.5 CBZ30174.1 - 3.8 8.1 8.3 0.19 12.3 1.1 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4766) RCS1 PF07326.11 CBZ30176.1 - 0.11 12.4 0.0 0.15 11.9 0.0 1.1 1 0 0 1 1 1 0 Regulator of chromosome segregation 1 Ribosomal_S6 PF01250.17 CBZ30177.1 - 0.0054 17.0 0.1 0.0085 16.3 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein S6 GAS PF13851.6 CBZ30178.1 - 3.4e-06 26.5 3.8 3.1e-05 23.4 0.3 2.4 2 0 0 2 2 2 1 Growth-arrest specific micro-tubule binding Fib_alpha PF08702.10 CBZ30178.1 - 0.01 16.1 3.4 0.21 11.7 0.2 2.7 3 0 0 3 3 3 1 Fibrinogen alpha/beta chain family Troponin PF00992.20 CBZ30178.1 - 0.029 14.7 0.8 0.029 14.7 0.8 2.5 2 1 0 2 2 2 0 Troponin Bap31_Bap29_C PF18035.1 CBZ30178.1 - 0.038 14.0 4.3 0.87 9.6 2.2 2.9 2 0 0 2 2 2 0 Bap31/Bap29 cytoplasmic coiled-coil domain EzrA PF06160.12 CBZ30178.1 - 0.11 10.7 3.9 0.13 10.4 0.5 2.1 2 0 0 2 2 2 0 Septation ring formation regulator, EzrA DUF4140 PF13600.6 CBZ30178.1 - 0.19 12.1 10.1 1.1 9.8 0.9 2.8 2 1 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) DUF4349 PF14257.6 CBZ30178.1 - 0.35 10.3 6.0 0.18 11.2 0.5 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4349) Med9 PF07544.13 CBZ30178.1 - 0.56 10.3 5.0 0.87 9.7 0.5 2.8 2 1 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 TSNAXIP1_N PF15739.5 CBZ30178.1 - 0.89 10.0 4.9 20 5.6 0.6 3.3 3 0 0 3 3 3 0 Translin-associated factor X-interacting N-terminus HrpB7 PF09486.10 CBZ30178.1 - 2.3 8.6 21.3 1 9.7 9.4 2.7 3 0 0 3 3 3 0 Bacterial type III secretion protein (HrpB7) CENP-Q PF13094.6 CBZ30178.1 - 6.2 7.0 13.3 0.61 10.3 2.2 2.6 2 0 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit TPR_MLP1_2 PF07926.12 CBZ30178.1 - 8.3 6.5 16.0 3.2 7.8 4.9 2.9 3 0 0 3 3 3 0 TPR/MLP1/MLP2-like protein Ribosomal_S25 PF03297.15 CBZ30181.1 - 2e-36 124.2 5.4 2.3e-36 124.0 5.4 1.1 1 0 0 1 1 1 1 S25 ribosomal protein DUF3516 PF12029.8 CBZ30181.1 - 0.13 11.3 1.4 0.17 10.9 1.4 1.2 1 1 0 1 1 1 0 Domain of unknown function (DUF3516) WD40 PF00400.32 CBZ30184.1 - 2.4e-37 126.3 24.2 4.4e-07 30.5 0.2 7.6 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBZ30184.1 - 3.5e-07 30.4 0.0 0.042 14.1 0.0 4.7 3 2 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Ion_trans PF00520.31 CBZ30185.1 - 3.1e-120 400.0 109.6 3.9e-38 131.1 21.1 4.2 4 0 0 4 4 4 4 Ion transport protein GPHH PF16905.5 CBZ30185.1 - 0.0041 16.8 0.0 0.0098 15.6 0.0 1.7 1 0 0 1 1 1 1 Voltage-dependent L-type calcium channel, IQ-associated HEAT PF02985.22 CBZ30186.1 - 3.2e-13 48.7 4.7 0.7 10.3 0.0 9.0 8 1 1 9 9 9 4 HEAT repeat HEAT_2 PF13646.6 CBZ30186.1 - 2.9e-10 40.4 3.1 0.013 15.8 0.0 6.1 4 2 1 5 5 5 4 HEAT repeats Arm PF00514.23 CBZ30186.1 - 7.4e-09 35.4 3.5 0.2 11.7 0.0 5.6 5 0 0 5 5 5 3 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 CBZ30186.1 - 2.9e-08 34.0 12.7 0.00011 22.6 0.1 6.6 5 3 2 7 7 7 2 HEAT-like repeat IBN_N PF03810.19 CBZ30186.1 - 2.5e-06 27.3 0.0 3e-05 23.8 0.0 3.0 2 1 0 2 2 2 1 Importin-beta N-terminal domain Adaptin_N PF01602.20 CBZ30186.1 - 6.8e-05 21.6 1.6 0.068 11.7 0.1 3.0 3 0 0 3 3 3 2 Adaptin N terminal region Vac14_Fab1_bd PF12755.7 CBZ30186.1 - 0.00016 22.2 2.5 0.74 10.5 0.1 4.9 4 2 1 6 6 6 1 Vacuolar 14 Fab1-binding region DUF3385 PF11865.8 CBZ30186.1 - 0.00028 20.9 2.4 2 8.3 0.1 5.3 4 2 2 6 6 6 1 Domain of unknown function (DUF3385) V-ATPase_H_C PF11698.8 CBZ30186.1 - 0.011 15.8 0.1 1.6 8.9 0.0 3.9 4 0 0 4 4 4 0 V-ATPase subunit H Spidroin_N PF16763.5 CBZ30186.1 - 0.026 14.6 0.6 8 6.5 0.0 3.3 2 0 0 2 2 2 0 Major ampullate spidroin 1, spider silk protein 1, N-term CLASP_N PF12348.8 CBZ30186.1 - 0.027 14.0 1.9 0.97 8.9 0.0 3.6 3 1 1 4 4 4 0 CLASP N terminal ApoLp-III PF07464.11 CBZ30186.1 - 0.042 14.0 0.4 0.67 10.0 0.1 2.8 2 0 0 2 2 2 0 Apolipophorin-III precursor (apoLp-III) Telomere_reg-2 PF10193.9 CBZ30186.1 - 0.099 13.1 4.0 9 6.8 0.1 4.3 3 1 1 4 4 4 0 Telomere length regulation protein U3snoRNP10 PF12397.8 CBZ30186.1 - 0.13 12.6 5.5 27 5.1 0.1 5.1 5 1 1 6 6 6 0 U3 small nucleolar RNA-associated protein 10 Amastin PF07344.11 CBZ30188.1 - 2.7e-46 157.3 12.2 3.1e-46 157.0 12.2 1.0 1 0 0 1 1 1 1 Amastin surface glycoprotein O-FucT PF10250.9 CBZ30189.1 - 0.091 12.4 0.1 0.36 10.5 0.0 1.9 2 0 0 2 2 2 0 GDP-fucose protein O-fucosyltransferase SNAP PF14938.6 CBZ30192.1 - 1.2e-07 31.4 21.1 2.3e-06 27.2 9.9 2.5 2 1 1 3 3 3 2 Soluble NSF attachment protein, SNAP TPR_12 PF13424.6 CBZ30192.1 - 3.7e-05 23.9 0.5 3.7e-05 23.9 0.5 3.2 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.17 CBZ30192.1 - 0.00027 20.8 9.7 0.032 14.3 0.2 5.5 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_1 PF00515.28 CBZ30192.1 - 0.00072 19.3 2.0 0.59 10.0 0.0 4.0 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_11 PF13414.6 CBZ30192.1 - 0.11 12.2 1.8 2.2 8.0 0.1 3.4 4 0 0 4 4 4 0 TPR repeat Clathrin PF00637.20 CBZ30192.1 - 0.15 12.0 0.5 16 5.3 0.0 2.7 2 0 0 2 2 2 0 Region in Clathrin and VPS TPR_16 PF13432.6 CBZ30192.1 - 0.49 11.1 15.0 0.49 11.1 0.3 5.0 5 1 0 5 5 5 0 Tetratricopeptide repeat TPR_14 PF13428.6 CBZ30192.1 - 1.2 10.1 7.6 20 6.3 0.1 4.6 5 0 0 5 5 5 0 Tetratricopeptide repeat LRR_4 PF12799.7 CBZ30193.1 - 1.5e-12 47.5 17.7 0.012 16.0 0.0 6.7 4 1 2 7 7 7 7 Leucine Rich repeats (2 copies) DUF641 PF04859.12 CBZ30193.1 - 0.076 13.3 1.5 7.2 7.0 0.0 2.8 3 0 0 3 3 3 0 Plant protein of unknown function (DUF641) MbeD_MobD PF04899.12 CBZ30193.1 - 0.58 10.3 10.1 2.8 8.1 10.1 2.1 1 0 0 1 1 1 0 MbeD/MobD like GTP_EFTU PF00009.27 CBZ30195.1 - 2.1e-43 148.2 0.2 3.2e-43 147.5 0.2 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain LepA_C PF06421.12 CBZ30195.1 - 1.4e-31 108.9 0.8 2.3e-31 108.1 0.8 1.4 1 0 0 1 1 1 1 GTP-binding protein LepA C-terminus EFG_C PF00679.24 CBZ30195.1 - 2.1e-13 50.1 0.0 3.9e-13 49.2 0.0 1.5 1 0 0 1 1 1 1 Elongation factor G C-terminus MMR_HSR1 PF01926.23 CBZ30195.1 - 0.00039 20.5 0.0 0.001 19.1 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase PduV-EutP PF10662.9 CBZ30195.1 - 0.00093 19.0 0.1 0.0099 15.6 0.1 2.4 3 0 0 3 3 3 1 Ethanolamine utilisation - propanediol utilisation GTP_EFTU_D2 PF03144.25 CBZ30195.1 - 0.0012 19.2 0.0 0.0029 18.0 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 Ras PF00071.22 CBZ30195.1 - 0.0024 17.5 0.1 0.0045 16.6 0.1 1.3 1 0 0 1 1 1 1 Ras family FeoB_N PF02421.18 CBZ30195.1 - 0.033 13.7 0.3 0.066 12.7 0.3 1.5 1 0 0 1 1 1 0 Ferrous iron transport protein B Septin PF00735.18 CBZ30195.1 - 0.035 13.4 0.2 0.59 9.4 0.0 2.1 2 0 0 2 2 2 0 Septin RsgA_GTPase PF03193.16 CBZ30195.1 - 0.11 12.4 0.0 0.41 10.5 0.0 1.9 2 0 0 2 2 2 0 RsgA GTPase DUF677 PF05055.12 CBZ30196.1 - 2.2e-05 23.5 2.2 2.7e-05 23.2 2.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF677) DUF4618 PF15397.6 CBZ30196.1 - 0.0008 18.9 4.3 0.0009 18.7 4.3 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4618) DUF812 PF05667.11 CBZ30196.1 - 0.0026 16.8 4.7 0.0027 16.7 4.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF812) Tho2 PF11262.8 CBZ30196.1 - 0.009 15.2 5.3 0.012 14.9 5.3 1.1 1 0 0 1 1 1 1 Transcription factor/nuclear export subunit protein 2 Phage_Mu_Gam PF07352.12 CBZ30196.1 - 0.024 14.5 5.0 0.024 14.5 5.0 1.7 1 1 1 2 2 2 0 Bacteriophage Mu Gam like protein FAM184 PF15665.5 CBZ30196.1 - 0.035 13.9 10.5 0.043 13.6 10.5 1.2 1 0 0 1 1 1 0 Family with sequence similarity 184, A and B SlyX PF04102.12 CBZ30196.1 - 0.041 14.5 5.9 0.97 10.1 2.1 2.3 1 1 1 2 2 2 0 SlyX Val_tRNA-synt_C PF10458.9 CBZ30196.1 - 0.051 13.9 7.6 0.51 10.7 2.3 2.9 2 1 0 2 2 2 0 Valyl tRNA synthetase tRNA binding arm ZapB PF06005.12 CBZ30196.1 - 0.091 13.2 12.8 0.081 13.4 11.2 1.7 1 1 0 1 1 1 0 Cell division protein ZapB DUF948 PF06103.11 CBZ30196.1 - 0.1 12.9 0.4 0.18 12.1 0.4 1.3 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) CCDC92 PF14916.6 CBZ30196.1 - 0.11 12.2 4.8 1 9.2 2.2 2.2 1 1 1 2 2 2 0 Coiled-coil domain of unknown function NPV_P10 PF05531.12 CBZ30196.1 - 0.12 12.9 0.7 0.22 12.0 0.7 1.4 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein LPP PF04728.13 CBZ30196.1 - 0.14 12.6 2.4 9.1 6.8 0.4 2.5 2 0 0 2 2 2 0 Lipoprotein leucine-zipper Ax_dynein_light PF10211.9 CBZ30196.1 - 0.15 12.0 9.0 0.18 11.7 9.0 1.2 1 0 0 1 1 1 0 Axonemal dynein light chain UPF0242 PF06785.11 CBZ30196.1 - 0.2 11.7 7.6 0.23 11.6 7.6 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Csm1_N PF18504.1 CBZ30196.1 - 0.25 11.7 9.8 2.6 8.5 1.2 2.5 1 1 1 2 2 2 0 Csm1 N-terminal domain DUF4446 PF14584.6 CBZ30196.1 - 0.5 10.4 6.8 0.54 10.2 4.6 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF4446) AAA_11 PF13086.6 CBZ30196.1 - 0.57 9.9 5.5 0.61 9.8 5.5 1.0 1 0 0 1 1 1 0 AAA domain KfrA_N PF11740.8 CBZ30196.1 - 0.66 10.7 6.4 1.4 9.6 6.4 1.8 1 1 0 1 1 1 0 Plasmid replication region DNA-binding N-term Pox_A_type_inc PF04508.12 CBZ30196.1 - 1.1 9.2 0.1 1.1 9.2 0.1 3.6 2 1 2 4 4 4 0 Viral A-type inclusion protein repeat Synaptobrevin PF00957.21 CBZ30196.1 - 2.5 8.0 5.6 2 8.2 4.2 1.6 2 0 0 2 2 1 0 Synaptobrevin TMPIT PF07851.13 CBZ30196.1 - 2.8 7.1 5.0 2.9 7.1 5.0 1.1 1 0 0 1 1 1 0 TMPIT-like protein YtxH PF12732.7 CBZ30196.1 - 3.2 8.4 6.0 10 6.7 5.9 2.1 1 1 0 1 1 1 0 YtxH-like protein DivIC PF04977.15 CBZ30196.1 - 4.6 7.1 12.3 8.2 6.3 3.0 2.8 2 1 1 3 3 3 0 Septum formation initiator DUF724 PF05266.14 CBZ30196.1 - 4.7 7.0 12.3 11 5.8 12.3 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF724) DUF883 PF05957.13 CBZ30196.1 - 5.9 7.6 8.5 0.72 10.5 4.1 1.8 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF883) RRF PF01765.19 CBZ30196.1 - 6.3 6.7 11.8 8.5 6.3 5.3 2.1 1 1 0 2 2 2 0 Ribosome recycling factor DUF3258 PF11646.8 CBZ30198.1 - 1.1 9.4 3.7 7.4 6.8 0.3 2.9 2 1 1 3 3 3 0 Protein of unknown function DUF3258 NMO PF03060.15 CBZ30199.1 - 9e-59 199.5 2.9 7.5e-39 134.0 2.6 2.0 1 1 1 2 2 2 2 Nitronate monooxygenase IMPDH PF00478.25 CBZ30199.1 - 1.4e-08 34.1 0.4 0.00027 20.0 1.3 2.2 1 1 0 2 2 2 2 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.18 CBZ30199.1 - 7.4e-08 31.8 0.9 1.2e-07 31.1 0.9 1.3 1 0 0 1 1 1 1 FMN-dependent dehydrogenase DHO_dh PF01180.21 CBZ30199.1 - 8.4e-05 21.9 0.1 0.00016 21.0 0.1 1.4 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase ThiG PF05690.14 CBZ30199.1 - 8.6e-05 22.0 1.4 0.00014 21.3 1.4 1.3 1 0 0 1 1 1 1 Thiazole biosynthesis protein ThiG Glu_synthase PF01645.17 CBZ30199.1 - 0.0052 16.0 0.5 0.0087 15.2 0.5 1.4 1 0 0 1 1 1 1 Conserved region in glutamate synthase Peripla_BP_6 PF13458.6 CBZ30199.1 - 0.024 14.3 1.6 0.58 9.8 1.7 2.3 1 1 1 2 2 2 0 Periplasmic binding protein ZnuA PF01297.17 CBZ30199.1 - 0.18 11.2 0.0 0.31 10.4 0.0 1.3 1 0 0 1 1 1 0 Zinc-uptake complex component A periplasmic Sec20 PF03908.13 CBZ30200.1 - 0.73 9.8 2.2 1.2 9.1 0.2 2.3 2 0 0 2 2 2 0 Sec20 DUF1759 PF03564.15 CBZ30200.1 - 0.88 9.5 2.2 3.3 7.6 0.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1759) COG5 PF10392.9 CBZ30200.1 - 1.1 9.5 3.2 32 4.7 0.2 3.0 2 0 0 2 2 2 0 Golgi transport complex subunit 5 DUF1664 PF07889.12 CBZ30200.1 - 8.5 6.4 11.9 0.92 9.6 0.4 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) Nup88 PF10168.9 CBZ30201.1 - 0.63 7.8 17.8 1.2 6.9 17.8 1.4 1 0 0 1 1 1 0 Nuclear pore component LMBR1 PF04791.16 CBZ30201.1 - 0.73 8.7 11.2 1.6 7.5 11.2 1.6 1 0 0 1 1 1 0 LMBR1-like membrane protein Baculo_PEP_C PF04513.12 CBZ30201.1 - 2.3 8.2 5.5 29 4.7 2.4 3.2 2 1 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Spc7 PF08317.11 CBZ30201.1 - 3.1 6.6 41.1 0.2 10.5 21.7 2.8 2 1 1 3 3 3 0 Spc7 kinetochore protein DUF1818 PF08848.11 CBZ30201.1 - 4.4 7.4 7.7 0.37 10.9 0.9 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF1818) Sec20 PF03908.13 CBZ30201.1 - 6.7 6.7 9.5 4.4 7.3 1.8 3.1 1 1 2 3 3 3 0 Sec20 LRR_8 PF13855.6 CBZ30202.1 - 0.00043 20.0 0.6 0.1 12.4 0.0 3.5 2 0 0 2 2 2 2 Leucine rich repeat LRR_6 PF13516.6 CBZ30202.1 - 0.0088 16.0 8.2 2.8 8.2 0.1 6.1 6 0 0 6 6 6 1 Leucine Rich repeat LRR_4 PF12799.7 CBZ30202.1 - 0.13 12.7 1.4 27 5.4 0.1 3.9 3 1 1 4 4 4 0 Leucine Rich repeats (2 copies) JAB PF01398.21 CBZ30203.1 - 8.7e-28 96.7 0.0 1.6e-27 95.8 0.0 1.4 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Prok-JAB PF14464.6 CBZ30203.1 - 3.3e-08 33.3 0.0 5.3e-08 32.6 0.0 1.4 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain MitMem_reg PF13012.6 CBZ30203.1 - 0.0022 18.4 0.2 0.0053 17.2 0.2 1.6 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function ABC_tran PF00005.27 CBZ30205.1 - 3.2e-39 134.6 0.0 8.2e-22 78.2 0.0 2.7 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 CBZ30205.1 - 3.4e-37 128.6 17.7 1.7e-21 77.1 4.0 3.3 3 0 0 3 3 3 2 ABC transporter transmembrane region SMC_N PF02463.19 CBZ30205.1 - 1.5e-08 34.4 1.1 0.0011 18.5 0.1 4.2 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 CBZ30205.1 - 1.9e-05 24.7 0.1 0.91 9.3 0.0 4.1 4 0 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system MMR_HSR1 PF01926.23 CBZ30205.1 - 1.9e-05 24.7 0.1 0.016 15.3 0.1 2.5 2 0 0 2 2 2 2 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 CBZ30205.1 - 2e-05 24.6 0.0 0.063 13.2 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA_29 PF13555.6 CBZ30205.1 - 0.0006 19.5 0.1 0.4 10.5 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.6 CBZ30205.1 - 0.002 18.6 5.4 0.032 14.6 0.0 3.9 2 2 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 CBZ30205.1 - 0.0025 18.1 0.0 0.12 12.6 0.0 3.0 2 1 0 2 2 2 1 AAA domain AAA PF00004.29 CBZ30205.1 - 0.0037 17.7 0.1 1.5 9.3 0.0 3.4 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_23 PF13476.6 CBZ30205.1 - 0.0067 17.0 0.1 1.9 8.9 0.0 2.3 2 0 0 2 2 2 1 AAA domain Dynamin_N PF00350.23 CBZ30205.1 - 0.0068 16.5 0.3 1 9.4 0.2 2.4 2 0 0 2 2 2 1 Dynamin family AIG1 PF04548.16 CBZ30205.1 - 0.014 14.8 0.6 1.3 8.3 0.1 2.4 2 0 0 2 2 2 0 AIG1 family AAA_25 PF13481.6 CBZ30205.1 - 0.024 14.2 0.2 0.47 10.0 0.0 3.1 3 0 0 3 3 3 0 AAA domain RNA_helicase PF00910.22 CBZ30205.1 - 0.08 13.3 0.1 4.5 7.7 0.0 3.0 3 0 0 3 3 3 0 RNA helicase ATPase_2 PF01637.18 CBZ30205.1 - 0.08 12.8 0.0 0.22 11.4 0.0 1.7 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea Transposase_20 PF02371.16 CBZ30205.1 - 0.65 10.3 3.8 0.36 11.2 0.1 2.5 3 0 0 3 3 3 0 Transposase IS116/IS110/IS902 family HHH_3 PF12836.7 CBZ30206.1 - 0.00095 19.4 0.6 4.1 7.7 0.0 3.3 3 0 0 3 3 3 2 Helix-hairpin-helix motif Fez1 PF06818.15 CBZ30206.1 - 0.0011 19.5 49.6 0.11 12.9 3.1 5.8 4 2 2 6 6 6 4 Fez1 DUF2529 PF10740.9 CBZ30206.1 - 0.0018 18.0 0.2 4 7.1 0.0 3.3 2 0 0 2 2 2 2 Domain of unknown function (DUF2529) HHH_2 PF12826.7 CBZ30206.1 - 0.006 16.6 9.8 1.6 8.9 0.0 4.5 5 0 0 5 5 4 2 Helix-hairpin-helix motif FlaC_arch PF05377.11 CBZ30206.1 - 0.045 14.1 17.1 0.17 12.3 0.2 5.9 6 0 0 6 6 6 0 Flagella accessory protein C (FlaC) Repressor_Mnt PF11423.8 CBZ30206.1 - 0.067 13.0 16.7 5 7.0 0.2 4.7 4 0 0 4 4 4 0 Regulatory protein Mnt Prominin PF05478.11 CBZ30206.1 - 0.15 10.0 1.0 0.32 8.9 1.0 1.5 1 0 0 1 1 1 0 Prominin Sec8_exocyst PF04048.14 CBZ30206.1 - 0.25 11.2 2.8 0.7 9.8 0.1 3.2 4 0 0 4 4 4 0 Sec8 exocyst complex component specific domain CENP-F_leu_zip PF10473.9 CBZ30206.1 - 0.28 11.2 51.4 1.3 9.1 0.6 6.6 7 1 1 8 8 8 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Fib_alpha PF08702.10 CBZ30206.1 - 3.5 7.8 6.7 32 4.7 0.1 3.7 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family tRNA_synt_1c_R2 PF04557.15 CBZ30206.1 - 4.1 8.4 14.8 23 6.0 0.6 4.3 3 0 0 3 3 3 0 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 2 DUF948 PF06103.11 CBZ30206.1 - 7.1 7.0 15.4 14 6.0 0.5 5.7 6 1 0 6 6 4 0 Bacterial protein of unknown function (DUF948) GAS PF13851.6 CBZ30206.1 - 7.3 5.9 64.3 0.0091 15.4 7.5 6.5 6 1 1 7 7 7 0 Growth-arrest specific micro-tubule binding MCC-bdg_PDZ PF10506.9 CBZ30207.1 - 4e-34 116.4 231.1 0.045 13.8 5.6 20.9 19 1 1 20 20 20 17 PDZ domain of MCC-2 bdg protein for Usher syndrome ERM PF00769.19 CBZ30207.1 - 7.3e-23 81.6 418.8 0.00011 22.1 34.9 13.1 3 2 8 13 13 13 9 Ezrin/radixin/moesin family PKcGMP_CC PF16808.5 CBZ30207.1 - 0.28 11.1 11.5 0.22 11.4 1.2 5.3 4 0 0 4 4 4 0 Coiled-coil N-terminus of cGMP-dependent protein kinase DUF2039 PF10217.9 CBZ30208.1 - 5.4e-23 81.2 23.4 8.1e-23 80.6 23.4 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2039) Tankyrase_bdg_C PF15327.6 CBZ30208.1 - 0.045 14.2 3.2 0.069 13.6 3.2 1.3 1 0 0 1 1 1 0 Tankyrase binding protein C terminal domain Cript PF10235.9 CBZ30208.1 - 4.1 8.0 19.9 27 5.4 19.9 2.2 1 1 0 1 1 1 0 Microtubule-associated protein CRIPT Transmemb_17 PF09799.9 CBZ30209.1 - 7.2e-20 71.6 9.2 1e-19 71.1 9.2 1.2 1 0 0 1 1 1 1 Predicted membrane protein Sod_Fe_C PF02777.18 CBZ30211.1 - 0.0021 18.2 0.0 0.0059 16.7 0.0 1.7 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, C-terminal domain Tcp10_C PF07202.13 CBZ30211.1 - 0.01 15.8 0.1 0.03 14.3 0.1 1.7 1 0 0 1 1 1 0 T-complex protein 10 C-terminus SpoIIE PF07228.12 CBZ30212.1 - 3.6e-08 33.5 0.0 5.1e-08 33.1 0.0 1.2 1 0 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) PP2C_2 PF13672.6 CBZ30212.1 - 0.012 15.2 0.0 0.017 14.8 0.0 1.4 1 0 0 1 1 1 0 Protein phosphatase 2C PP2C PF00481.21 CBZ30212.1 - 0.02 14.5 0.0 0.035 13.8 0.0 1.3 1 0 0 1 1 1 0 Protein phosphatase 2C CBF PF03914.17 CBZ30213.1 - 2e-27 96.3 0.5 3e-27 95.7 0.5 1.3 1 0 0 1 1 1 1 CBF/Mak21 family DUF4844 PF16133.5 CBZ30214.1 - 0.065 13.8 0.1 2.9 8.5 0.1 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF4844) NAD_binding_10 PF13460.6 CBZ30215.1 - 3e-06 27.2 0.0 0.0012 18.8 0.0 2.3 2 0 0 2 2 2 2 NAD(P)H-binding Shikimate_DH PF01488.20 CBZ30215.1 - 0.00036 20.6 0.1 0.0006 19.9 0.1 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NmrA PF05368.13 CBZ30215.1 - 0.00094 18.8 0.2 0.0022 17.6 0.0 1.6 2 0 0 2 2 2 1 NmrA-like family 3HCDH_N PF02737.18 CBZ30215.1 - 0.0069 16.3 0.0 0.01 15.7 0.0 1.2 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain adh_short PF00106.25 CBZ30215.1 - 0.064 12.7 0.0 0.1 12.1 0.0 1.3 1 0 0 1 1 1 0 short chain dehydrogenase Epimerase PF01370.21 CBZ30215.1 - 0.075 12.5 0.0 0.6 9.5 0.0 2.0 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 CBZ30215.1 - 0.13 11.5 0.0 0.2 10.8 0.0 1.2 1 0 0 1 1 1 0 Male sterility protein Tub_N PF16322.5 CBZ30216.1 - 0.02 15.3 6.1 0.024 15.1 6.1 1.1 1 0 0 1 1 1 0 Tubby N-terminal Dabb PF07876.12 CBZ30216.1 - 2.6 8.7 5.5 0.37 11.4 1.3 1.7 2 0 0 2 2 2 0 Stress responsive A/B Barrel Domain Metallophos PF00149.28 CBZ30217.1 - 1.3e-32 114.0 0.1 1.7e-32 113.6 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 CBZ30217.1 - 9.8e-12 45.1 1.1 1.6e-11 44.5 1.1 1.3 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain Metallophos PF00149.28 CBZ30218.1 - 1.6e-31 110.4 0.1 2.1e-31 110.0 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 CBZ30218.1 - 4.2e-13 49.5 1.4 6.9e-13 48.8 1.4 1.4 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain Metallophos PF00149.28 CBZ30219.1 - 2.9e-32 112.8 0.1 3.8e-32 112.5 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 CBZ30219.1 - 3.6e-13 49.7 0.4 5.6e-13 49.1 0.4 1.3 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain Metallophos PF00149.28 CBZ30220.1 - 1.8e-31 110.3 0.1 2.3e-31 109.9 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 CBZ30220.1 - 1.6e-14 54.1 1.9 2.5e-14 53.4 1.9 1.3 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain Pcc1 PF09341.10 CBZ30221.1 - 5e-11 42.6 0.1 1.1e-10 41.5 0.1 1.6 1 0 0 1 1 1 1 Transcription factor Pcc1 EF1_GNE PF00736.19 CBZ30222.1 - 1.8e-26 92.1 1.3 3e-26 91.4 1.3 1.4 1 0 0 1 1 1 1 EF-1 guanine nucleotide exchange domain GST_C_2 PF13410.6 CBZ30222.1 - 0.028 14.4 0.0 0.068 13.2 0.0 1.8 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain DUF740 PF05340.12 CBZ30222.1 - 0.1 11.3 0.1 0.12 11.1 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF740) GST_C_2 PF13410.6 CBZ30223.1 - 0.0042 17.1 0.1 0.0071 16.4 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain AsnC_trans_reg PF01037.21 CBZ30223.1 - 0.11 12.5 0.0 0.13 12.3 0.0 1.2 1 0 0 1 1 1 0 Lrp/AsnC ligand binding domain EF1_GNE PF00736.19 CBZ30224.1 - 3.2e-26 91.3 1.3 5.1e-26 90.7 1.3 1.3 1 0 0 1 1 1 1 EF-1 guanine nucleotide exchange domain GST_C_2 PF13410.6 CBZ30224.1 - 0.04 13.9 0.0 0.098 12.7 0.0 1.7 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Metallophos PF00149.28 CBZ30225.1 - 1.3e-32 114.0 0.0 1.5e-32 113.8 0.0 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 CBZ30225.1 - 1.7e-05 25.2 0.0 3.1e-05 24.3 0.0 1.5 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain Ribosomal_L13 PF00572.18 CBZ30226.1 - 8.9e-06 26.0 3.7 0.00036 20.8 0.1 2.6 2 1 1 3 3 3 2 Ribosomal protein L13 DUF4455 PF14643.6 CBZ30226.1 - 0.031 13.0 0.8 0.043 12.5 0.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4455) RNA_pol_Rpb6 PF01192.22 CBZ30229.1 - 3e-14 52.7 0.2 5.7e-14 51.8 0.2 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb6 UQ_con PF00179.26 CBZ30230.1 - 2e-16 59.9 0.0 3.1e-16 59.3 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Med3 PF11593.8 CBZ30230.1 - 0.076 12.2 4.9 0.094 11.9 4.9 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal DUF2046 PF09755.9 CBZ30232.1 - 0.077 12.2 7.1 0.1 11.8 5.4 2.0 2 1 0 2 2 2 0 Uncharacterized conserved protein H4 (DUF2046) Flagellar_rod PF05149.12 CBZ30232.1 - 0.23 10.9 11.3 0.41 10.1 11.3 1.3 1 0 0 1 1 1 0 Paraflagellar rod protein zf-Tim10_DDP PF02953.15 CBZ30233.1 - 0.016 14.8 1.9 0.041 13.5 0.0 2.1 2 0 0 2 2 2 0 Tim10/DDP family zinc finger Pkinase PF00069.25 CBZ30234.1 - 1.1e-40 139.7 0.0 1.5e-30 106.5 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ30234.1 - 2.3e-19 69.7 0.0 2.5e-14 53.2 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kdo PF06293.14 CBZ30234.1 - 0.022 14.1 0.0 0.038 13.3 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Rhodanese PF00581.20 CBZ30235.1 - 5e-08 33.4 0.0 0.005 17.3 0.0 3.1 2 1 0 2 2 2 2 Rhodanese-like domain EMI PF07546.13 CBZ30235.1 - 0.021 15.6 1.0 0.064 14.0 1.0 1.8 1 0 0 1 1 1 0 EMI domain Amastin PF07344.11 CBZ30236.1 - 1.6e-55 187.2 10.3 1.8e-55 187.0 10.3 1.0 1 0 0 1 1 1 1 Amastin surface glycoprotein SUR7 PF06687.12 CBZ30236.1 - 0.46 10.1 23.3 0.12 12.0 7.3 3.0 1 1 1 3 3 3 0 SUR7/PalI family Claudin_2 PF13903.6 CBZ30236.1 - 0.59 9.9 8.4 0.05 13.4 2.5 2.0 2 0 0 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction MFS_1_like PF12832.7 CBZ30236.1 - 0.9 8.3 6.2 0.33 9.8 3.0 1.9 2 0 0 2 2 2 0 MFS_1 like family Amastin PF07344.11 CBZ30237.1 - 1.5e-54 184.1 12.1 1.7e-54 183.9 12.1 1.0 1 0 0 1 1 1 1 Amastin surface glycoprotein SUR7 PF06687.12 CBZ30237.1 - 0.048 13.3 23.6 0.016 14.8 5.8 3.0 2 1 1 3 3 3 0 SUR7/PalI family CrgA PF06781.12 CBZ30237.1 - 2.5 8.2 10.1 0.076 13.1 3.5 1.9 2 0 0 2 2 2 0 Cell division protein CrgA PRA1 PF03208.19 CBZ30237.1 - 3.5 7.3 11.9 2.2 7.9 9.5 1.9 1 1 0 1 1 1 0 PRA1 family protein Amastin PF07344.11 CBZ30238.1 - 5.1e-48 162.8 9.1 6.1e-48 162.6 9.1 1.1 1 0 0 1 1 1 1 Amastin surface glycoprotein DUF4064 PF13273.6 CBZ30238.1 - 1.6 9.0 10.1 0.96 9.8 0.1 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF4064) SUR7 PF06687.12 CBZ30238.1 - 3 7.4 16.9 6 6.4 0.1 3.0 2 1 1 3 3 3 0 SUR7/PalI family Amastin PF07344.11 CBZ30239.1 - 4.8e-38 130.4 13.6 5.7e-38 130.2 13.6 1.1 1 0 0 1 1 1 1 Amastin surface glycoprotein ABC_membrane PF00664.23 CBZ30240.1 - 1.1e-130 435.2 16.6 1.6e-72 244.4 8.5 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 CBZ30240.1 - 6e-68 227.6 0.0 1.1e-32 113.4 0.0 2.4 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 CBZ30240.1 - 2.7e-13 49.8 1.2 3.3e-06 26.7 0.0 3.8 2 2 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 CBZ30240.1 - 2.7e-06 27.9 0.3 0.021 15.2 0.0 2.7 2 1 0 2 2 2 2 AAA ATPase domain RsgA_GTPase PF03193.16 CBZ30240.1 - 5.4e-06 26.4 0.0 0.15 12.0 0.0 2.7 2 0 0 2 2 2 2 RsgA GTPase AAA PF00004.29 CBZ30240.1 - 3.6e-05 24.2 0.0 1.1 9.6 0.1 3.6 3 1 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 CBZ30240.1 - 5.4e-05 23.5 0.9 0.019 15.2 0.0 3.6 2 2 0 2 2 2 1 AAA domain Zeta_toxin PF06414.12 CBZ30240.1 - 5.5e-05 22.5 0.0 0.22 10.8 0.0 2.4 2 0 0 2 2 2 2 Zeta toxin ATP-synt_ab PF00006.25 CBZ30240.1 - 7.7e-05 22.4 0.0 0.11 12.1 0.0 2.7 2 0 0 2 2 2 2 ATP synthase alpha/beta family, nucleotide-binding domain AAA_29 PF13555.6 CBZ30240.1 - 0.00025 20.7 1.3 0.72 9.6 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain ABC_ATPase PF09818.9 CBZ30240.1 - 0.00097 18.0 0.0 0.2 10.4 0.0 2.3 2 0 0 2 2 2 1 Predicted ATPase of the ABC class AAA_5 PF07728.14 CBZ30240.1 - 0.001 19.1 0.0 0.028 14.4 0.0 2.8 3 0 0 3 3 2 1 AAA domain (dynein-related subfamily) AAA_15 PF13175.6 CBZ30240.1 - 0.0017 18.1 0.0 0.11 12.2 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain AAA_7 PF12775.7 CBZ30240.1 - 0.0023 17.5 0.0 1.5 8.3 0.0 2.4 2 0 0 2 2 2 2 P-loop containing dynein motor region G-alpha PF00503.20 CBZ30240.1 - 0.0071 15.6 0.0 1.2 8.3 0.0 2.2 2 0 0 2 2 2 1 G-protein alpha subunit AAA_23 PF13476.6 CBZ30240.1 - 0.0072 16.8 0.3 0.11 13.0 0.1 2.2 2 0 0 2 2 2 1 AAA domain DUF2852 PF11014.8 CBZ30240.1 - 0.01 16.0 1.3 4.3 7.5 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2852) MeaB PF03308.16 CBZ30240.1 - 0.014 14.4 0.0 0.3 10.0 0.0 2.3 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB SbcCD_C PF13558.6 CBZ30240.1 - 0.018 15.2 6.1 8.6 6.7 0.3 4.7 3 2 0 3 3 3 0 Putative exonuclease SbcCD, C subunit DUF815 PF05673.13 CBZ30240.1 - 0.02 14.1 0.1 1.4 8.0 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF815) RNA_helicase PF00910.22 CBZ30240.1 - 0.024 15.0 0.3 6.4 7.2 0.0 2.5 2 0 0 2 2 2 0 RNA helicase AAA_21 PF13304.6 CBZ30240.1 - 0.041 13.7 0.0 0.51 10.1 0.0 2.4 2 1 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system MoaE PF02391.17 CBZ30240.1 - 0.058 13.7 0.2 3.2 8.1 0.0 3.1 3 0 0 3 3 3 0 MoaE protein Rad17 PF03215.15 CBZ30240.1 - 0.068 13.1 0.2 2.5 8.0 0.0 2.4 2 0 0 2 2 2 0 Rad17 P-loop domain AAA_30 PF13604.6 CBZ30240.1 - 0.069 12.9 0.8 5 6.8 0.1 3.0 3 1 0 3 3 3 0 AAA domain Viral_helicase1 PF01443.18 CBZ30240.1 - 0.079 12.7 0.5 1.8 8.3 0.1 2.5 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase MMR_HSR1 PF01926.23 CBZ30240.1 - 0.14 12.3 0.9 8.2 6.5 0.0 3.4 3 0 0 3 3 3 0 50S ribosome-binding GTPase Abhydrolase_9_N PF15420.6 CBZ30240.1 - 4.7 7.2 14.4 0.031 14.3 2.0 3.2 4 0 0 4 4 3 0 Alpha/beta-hydrolase family N-terminus TatC PF00902.18 CBZ30240.1 - 5.7 6.7 12.7 4.6 7.0 1.6 3.0 3 0 0 3 3 3 0 Sec-independent protein translocase protein (TatC) Myosin_head PF00063.21 CBZ30241.1 - 1.8e-210 700.7 0.0 8.6e-210 698.4 0.0 1.8 1 1 0 1 1 1 1 Myosin head (motor domain) Myosin_TH1 PF06017.13 CBZ30241.1 - 5.1e-07 29.5 0.0 0.03 14.0 0.1 3.1 3 0 0 3 3 3 2 Unconventional myosin tail, actin- and lipid-binding FYVE PF01363.21 CBZ30241.1 - 2.4e-05 24.4 7.4 6.1e-05 23.1 7.4 1.6 1 0 0 1 1 1 1 FYVE zinc finger AAA_11 PF13086.6 CBZ30241.1 - 0.013 15.3 3.3 1.5 8.5 2.7 2.3 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 CBZ30241.1 - 0.031 14.7 2.7 0.041 14.3 0.0 2.4 2 0 0 2 2 2 0 AAA ATPase domain ABC_tran PF00005.27 CBZ30241.1 - 0.15 12.6 0.0 0.43 11.1 0.0 1.7 1 0 0 1 1 1 0 ABC transporter GP63 PF17471.2 CBZ30242.1 - 0.14 12.3 0.0 3.1 8.0 0.0 2.5 2 0 0 2 2 2 0 Gene product 63 N2227 PF07942.12 CBZ30243.1 - 8.7e-94 313.7 0.0 1.1e-93 313.4 0.0 1.1 1 0 0 1 1 1 1 N2227-like protein EF-hand_7 PF13499.6 CBZ30244.1 - 1.7e-09 38.0 0.0 2.6e-09 37.4 0.0 1.3 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_8 PF13833.6 CBZ30244.1 - 5.5e-09 35.7 0.1 9.8e-09 34.9 0.1 1.4 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.32 CBZ30244.1 - 2.2e-06 26.8 0.1 0.00062 19.1 0.2 3.0 2 1 1 3 3 3 1 EF hand EF-hand_6 PF13405.6 CBZ30244.1 - 4.3e-05 23.1 0.1 0.036 14.0 0.1 3.0 1 1 1 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 CBZ30244.1 - 0.00053 19.4 1.2 0.0013 18.1 0.1 2.2 2 0 0 2 2 2 1 EF hand EF-hand_4 PF12763.7 CBZ30244.1 - 0.24 11.4 0.0 0.51 10.3 0.0 1.5 2 0 0 2 2 2 0 Cytoskeletal-regulatory complex EF hand UPRTase PF14681.6 CBZ30245.1 - 2.6e-70 236.1 0.0 3.2e-70 235.8 0.0 1.0 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.27 CBZ30245.1 - 4.8e-06 26.2 0.0 7.2e-06 25.6 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosyl transferase domain SET PF00856.28 CBZ30246.1 - 3.5e-13 50.3 0.0 9.6e-13 48.9 0.0 1.9 2 1 0 2 2 2 1 SET domain TPR_2 PF07719.17 CBZ30246.1 - 6.6e-08 32.1 9.7 0.00063 19.7 0.2 5.5 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_14 PF13428.6 CBZ30246.1 - 0.0032 18.2 3.9 0.087 13.7 0.0 4.4 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_12 PF13424.6 CBZ30246.1 - 0.0046 17.2 6.6 0.061 13.6 0.2 4.0 4 1 0 4 4 4 1 Tetratricopeptide repeat TPR_1 PF00515.28 CBZ30246.1 - 0.0077 16.0 13.5 0.0092 15.8 0.3 4.6 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_8 PF13181.6 CBZ30246.1 - 0.041 14.1 1.5 0.42 11.0 0.1 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_10 PF13374.6 CBZ30246.1 - 0.061 13.2 2.2 0.48 10.4 0.4 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.6 CBZ30246.1 - 0.17 12.0 2.8 3 8.1 0.2 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat Peptidase_M41 PF01434.18 CBZ30247.1 - 1e-39 136.4 0.0 1.6e-39 135.7 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.29 CBZ30247.1 - 2.4e-39 134.8 0.0 4.3e-39 134.0 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 CBZ30247.1 - 6.8e-11 41.8 0.1 1.8e-10 40.4 0.1 1.7 1 0 0 1 1 1 1 AAA+ lid domain AAA_2 PF07724.14 CBZ30247.1 - 0.00021 21.4 0.0 0.00049 20.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 CBZ30247.1 - 0.00025 21.5 0.0 0.11 12.9 0.1 2.7 1 1 1 2 2 2 1 AAA ATPase domain RuvB_N PF05496.12 CBZ30247.1 - 0.00038 20.2 0.0 0.001 18.8 0.0 1.7 2 0 0 2 2 1 1 Holliday junction DNA helicase RuvB P-loop domain TIP49 PF06068.13 CBZ30247.1 - 0.0025 17.1 0.0 0.0042 16.3 0.0 1.3 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_22 PF13401.6 CBZ30247.1 - 0.0067 16.7 0.0 0.4 11.0 0.0 2.5 1 1 0 2 2 2 1 AAA domain AAA_5 PF07728.14 CBZ30247.1 - 0.011 15.7 1.2 0.15 12.0 0.3 3.1 3 1 0 3 3 3 0 AAA domain (dynein-related subfamily) AAA_25 PF13481.6 CBZ30247.1 - 0.019 14.6 0.2 3.3 7.2 0.0 2.6 1 1 1 2 2 2 0 AAA domain AAA_14 PF13173.6 CBZ30247.1 - 0.025 14.6 0.0 0.048 13.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 CBZ30247.1 - 0.047 13.4 0.1 0.094 12.4 0.1 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein Mg_chelatase PF01078.21 CBZ30247.1 - 0.054 12.9 0.1 0.15 11.4 0.1 1.7 1 1 1 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_18 PF13238.6 CBZ30247.1 - 0.12 13.0 0.0 0.77 10.3 0.0 2.4 2 0 0 2 2 2 0 AAA domain Lipase_3 PF01764.25 CBZ30248.1 - 1.6e-07 31.3 0.0 3.9e-07 30.0 0.0 1.6 1 0 0 1 1 1 1 Lipase (class 3) Hydrolase_4 PF12146.8 CBZ30248.1 - 7.6e-05 22.1 0.0 0.00014 21.2 0.0 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 CBZ30248.1 - 0.00028 21.5 1.3 0.0028 18.3 0.1 2.8 2 0 0 2 2 2 1 Alpha/beta hydrolase family DUF2974 PF11187.8 CBZ30248.1 - 0.0011 18.6 0.1 0.0044 16.6 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF2974) TMEM43 PF07787.12 CBZ30248.1 - 0.02 14.3 2.8 0.046 13.1 2.8 1.6 1 0 0 1 1 1 0 Transmembrane protein 43 Abhydrolase_5 PF12695.7 CBZ30248.1 - 0.053 13.3 0.0 0.11 12.2 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase family Thioesterase PF00975.20 CBZ30248.1 - 0.058 13.5 0.1 0.13 12.4 0.1 1.5 1 0 0 1 1 1 0 Thioesterase domain Abhydrolase_1 PF00561.20 CBZ30248.1 - 0.058 13.0 0.0 0.13 11.9 0.0 1.5 1 0 0 1 1 1 0 alpha/beta hydrolase fold DUF1409 PF07197.12 CBZ30248.1 - 0.15 12.0 0.1 28 4.7 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1409) PGAP1 PF07819.13 CBZ30248.1 - 0.15 11.7 0.0 0.31 10.7 0.0 1.5 1 0 0 1 1 1 0 PGAP1-like protein Acyltransferase PF01553.21 CBZ30249.1 - 7.3e-19 67.7 0.0 2e-18 66.3 0.0 1.7 1 0 0 1 1 1 1 Acyltransferase SBDS PF01172.18 CBZ30251.1 - 3.8e-24 84.6 0.5 6.7e-24 83.8 0.5 1.4 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein SBDS_C PF09377.10 CBZ30251.1 - 4.2e-24 84.8 0.0 9.3e-24 83.7 0.0 1.6 1 0 0 1 1 1 1 SBDS protein C-terminal domain COPI_C PF06957.11 CBZ30251.1 - 1.4 7.6 7.8 2.6 6.7 7.8 1.4 1 0 0 1 1 1 0 Coatomer (COPI) alpha subunit C-terminus CH_2 PF06294.11 CBZ30252.1 - 9.7e-31 105.8 0.0 1.8e-30 104.9 0.0 1.4 1 0 0 1 1 1 1 CH-like domain in sperm protein CAMSAP_CH PF11971.8 CBZ30252.1 - 4.2e-19 68.2 0.0 7.3e-19 67.4 0.0 1.4 1 0 0 1 1 1 1 CAMSAP CH domain TMF_DNA_bd PF12329.8 CBZ30252.1 - 0.029 14.4 2.1 0.17 11.9 2.3 1.9 1 1 0 1 1 1 0 TATA element modulatory factor 1 DNA binding T2SSK PF03934.13 CBZ30252.1 - 0.11 11.9 0.3 5.1 6.4 0.0 2.1 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein K Csm1_N PF18504.1 CBZ30252.1 - 0.11 12.8 3.9 0.097 13.0 1.8 1.9 2 0 0 2 2 2 0 Csm1 N-terminal domain CH PF00307.31 CBZ30252.1 - 0.13 12.4 0.0 0.24 11.6 0.0 1.4 1 0 0 1 1 1 0 Calponin homology (CH) domain PKcGMP_CC PF16808.5 CBZ30252.1 - 0.28 11.1 2.5 5.5 6.9 0.0 2.4 2 0 0 2 2 2 0 Coiled-coil N-terminus of cGMP-dependent protein kinase TMEM52 PF14979.6 CBZ30253.1 - 2.1 8.3 9.0 1.7 8.6 0.1 3.7 3 0 0 3 3 3 0 Transmembrane 52 Dus PF01207.17 CBZ30254.1 - 1.2e-53 182.3 0.0 7.8e-52 176.3 0.0 2.1 1 1 0 1 1 1 1 Dihydrouridine synthase (Dus) BMC PF00936.19 CBZ30254.1 - 0.0049 16.8 0.7 0.035 14.1 0.0 2.3 2 0 0 2 2 2 1 BMC domain ThiG PF05690.14 CBZ30254.1 - 0.011 15.0 0.0 0.018 14.3 0.0 1.3 1 0 0 1 1 1 0 Thiazole biosynthesis protein ThiG His_biosynth PF00977.21 CBZ30254.1 - 0.015 14.7 0.0 0.036 13.5 0.0 1.5 2 0 0 2 2 2 0 Histidine biosynthesis protein DUF167 PF02594.16 CBZ30256.1 - 9.4e-14 51.3 0.8 2.3e-09 37.2 0.0 2.5 2 0 0 2 2 2 2 Uncharacterised ACR, YggU family COG1872 Cnn_1N PF07989.11 CBZ30258.1 - 0.012 15.8 5.3 0.012 15.8 5.3 6.8 3 2 1 5 5 5 0 Centrosomin N-terminal motif 1 REF PF05755.12 CBZ30258.1 - 0.9 9.3 3.3 2.2 8.0 3.3 1.6 1 0 0 1 1 1 0 Rubber elongation factor protein (REF) HA2 PF04408.23 CBZ30261.1 - 4e-13 49.6 0.0 1.3e-12 47.9 0.0 1.9 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.31 CBZ30261.1 - 7.4e-12 45.6 0.1 5.8e-11 42.7 0.0 2.4 2 1 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 CBZ30261.1 - 7.9e-11 42.0 0.1 1.8e-10 40.9 0.1 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase dsrm PF00035.26 CBZ30261.1 - 0.00012 22.7 0.1 0.04 14.6 0.1 3.4 3 0 0 3 3 3 1 Double-stranded RNA binding motif AAA_19 PF13245.6 CBZ30261.1 - 0.0019 18.5 0.0 0.0057 17.0 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 CBZ30261.1 - 0.0075 16.5 0.0 0.024 14.9 0.0 1.8 1 0 0 1 1 1 1 AAA domain Rad17 PF03215.15 CBZ30261.1 - 0.024 14.6 0.0 0.047 13.6 0.0 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain T2SSE PF00437.20 CBZ30261.1 - 0.033 13.2 0.0 0.063 12.3 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein F-box PF00646.33 CBZ30263.1 - 0.025 14.4 0.4 0.051 13.5 0.4 1.5 1 0 0 1 1 1 0 F-box domain Exo_endo_phos PF03372.23 CBZ30264.1 - 7.6e-05 22.3 0.0 0.00019 21.0 0.0 1.7 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family YabA PF06156.13 CBZ30265.1 - 0.026 15.2 3.4 0.071 13.7 0.9 2.7 2 0 0 2 2 2 0 Initiation control protein YabA HALZ PF02183.18 CBZ30265.1 - 0.093 13.0 4.4 0.17 12.1 1.7 2.5 2 0 0 2 2 2 0 Homeobox associated leucine zipper Shugoshin_N PF07558.11 CBZ30265.1 - 0.11 12.4 4.6 0.14 12.1 1.5 2.4 2 0 0 2 2 2 0 Shugoshin N-terminal coiled-coil region Vps51 PF08700.11 CBZ30265.1 - 0.24 11.5 5.3 0.43 10.7 2.4 2.5 2 0 0 2 2 2 0 Vps51/Vps67 DUF2205 PF10224.9 CBZ30265.1 - 0.76 9.8 4.2 6.5 6.8 4.2 2.5 1 1 0 1 1 1 0 Short coiled-coil protein DUF1640 PF07798.11 CBZ30265.1 - 2.6 8.1 9.2 8.5 6.4 9.2 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1640) DivIC PF04977.15 CBZ30265.1 - 2.7 7.8 8.8 7.1 6.5 3.0 2.8 2 1 0 2 2 2 0 Septum formation initiator bZIP_1 PF00170.21 CBZ30265.1 - 2.9 8.0 5.3 1.1 9.4 1.0 2.5 2 1 1 3 3 3 0 bZIP transcription factor TSC22 PF01166.18 CBZ30265.1 - 7 7.1 7.7 5.6 7.4 0.5 3.1 3 0 0 3 3 3 0 TSC-22/dip/bun family Fungal_TACC PF12709.7 CBZ30265.1 - 8.8 6.8 7.7 13 6.3 0.6 3.0 2 1 1 3 3 3 0 Fungal Transforming acidic coiled-coil (TACC) proteins DNA_pol_A_exo1 PF01612.20 CBZ30266.1 - 9.5e-14 51.5 0.1 3.9e-13 49.5 0.0 2.1 2 1 0 2 2 2 1 3'-5' exonuclease zf-CCCH PF00642.24 CBZ30266.1 - 0.00065 19.5 0.1 0.0014 18.5 0.1 1.6 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) WH2 PF02205.20 CBZ30266.1 - 0.0063 16.3 0.2 0.013 15.3 0.2 1.5 1 0 0 1 1 1 1 WH2 motif Torus PF16131.5 CBZ30266.1 - 0.03 15.0 0.7 0.13 13.0 0.0 2.4 2 0 0 2 2 2 0 Torus domain TPR_15 PF13429.6 CBZ30267.1 - 0.034 13.4 0.1 0.037 13.2 0.1 1.1 1 0 0 1 1 1 0 Tetratricopeptide repeat NIF PF03031.18 CBZ30268.1 - 1.2e-31 109.7 0.1 1.5e-29 102.8 0.1 3.0 2 1 0 2 2 2 1 NLI interacting factor-like phosphatase Ntox34 PF15606.6 CBZ30268.1 - 0.0082 16.2 0.0 0.02 15.0 0.0 1.6 1 0 0 1 1 1 1 Bacterial toxin 34 BtrH_N PF14399.6 CBZ30268.1 - 0.073 13.3 0.0 0.15 12.3 0.0 1.5 1 0 0 1 1 1 0 Butirosin biosynthesis protein H, N-terminal Bac_chlorC PF02043.17 CBZ30268.1 - 0.18 11.8 0.0 0.3 11.1 0.0 1.3 1 0 0 1 1 1 0 Bacteriochlorophyll C binding protein DNA_pol_A PF00476.20 CBZ30269.1 - 7.1e-95 318.2 0.0 5.4e-83 279.1 0.0 2.1 2 0 0 2 2 2 2 DNA polymerase family A Piezo_RRas_bdg PF12166.8 CBZ30270.1 - 1.3e-89 301.4 0.0 1.7e-89 301.0 0.0 1.1 1 0 0 1 1 1 1 Piezo non-specific cation channel, R-Ras-binding domain NCD3G PF07562.14 CBZ30270.1 - 0.11 12.5 1.7 4.7 7.3 0.4 2.7 2 0 0 2 2 2 0 Nine Cysteines Domain of family 3 GPCR LRR_6 PF13516.6 CBZ30272.1 - 3.9e-05 23.4 0.6 5.8 7.2 0.0 5.1 4 0 0 4 4 4 2 Leucine Rich repeat DUF5073 PF16817.5 CBZ30272.1 - 0.24 11.5 0.6 0.71 9.9 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF5073) OsmC PF02566.19 CBZ30273.1 - 2.1e-06 28.2 0.6 3.9e-06 27.3 0.6 1.4 1 0 0 1 1 1 1 OsmC-like protein FRG PF08867.11 CBZ30273.1 - 0.17 12.8 0.5 0.41 11.6 0.5 1.6 1 0 0 1 1 1 0 FRG domain BCS1_N PF08740.11 CBZ30276.1 - 8.6e-30 104.1 2.6 1.4e-29 103.4 2.6 1.4 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.29 CBZ30276.1 - 5.2e-20 72.2 0.0 1.5e-19 70.7 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 CBZ30276.1 - 0.0001 22.8 0.5 0.0015 19.0 0.1 2.3 1 1 1 2 2 2 1 AAA ATPase domain RuvB_N PF05496.12 CBZ30276.1 - 0.00036 20.3 0.0 0.00078 19.2 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 CBZ30276.1 - 0.00038 20.5 0.3 0.0035 17.3 0.3 2.5 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) ABC_tran PF00005.27 CBZ30276.1 - 0.00074 20.0 0.0 0.0016 19.0 0.0 1.6 1 0 0 1 1 1 1 ABC transporter DUF815 PF05673.13 CBZ30276.1 - 0.0023 17.1 0.0 0.0057 15.8 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF815) Rad17 PF03215.15 CBZ30276.1 - 0.0028 17.6 0.0 0.017 15.0 0.0 2.2 1 1 1 2 2 2 1 Rad17 P-loop domain AAA_11 PF13086.6 CBZ30276.1 - 0.0063 16.3 0.0 0.012 15.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 CBZ30276.1 - 0.0096 16.2 0.1 0.1 12.8 0.0 2.4 2 1 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 CBZ30276.1 - 0.01 16.2 0.0 0.024 15.0 0.0 1.7 1 0 0 1 1 1 1 RNA helicase AAA_18 PF13238.6 CBZ30276.1 - 0.018 15.6 0.0 0.037 14.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 CBZ30276.1 - 0.022 14.9 0.0 0.044 14.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 CBZ30276.1 - 0.031 14.2 0.0 0.13 12.2 0.0 2.1 1 0 0 1 1 1 0 NACHT domain ATPase_2 PF01637.18 CBZ30276.1 - 0.031 14.2 0.0 2.2 8.1 0.0 2.3 1 1 1 2 2 2 0 ATPase domain predominantly from Archaea TIP49 PF06068.13 CBZ30276.1 - 0.049 12.8 0.0 0.076 12.2 0.0 1.2 1 0 0 1 1 1 0 TIP49 P-loop domain AAA_14 PF13173.6 CBZ30276.1 - 0.07 13.2 0.0 0.15 12.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 CBZ30276.1 - 0.085 13.1 0.2 0.35 11.1 0.0 2.1 2 1 0 2 2 2 0 AAA domain Viral_helicase1 PF01443.18 CBZ30276.1 - 0.11 12.2 0.0 0.19 11.4 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_25 PF13481.6 CBZ30276.1 - 0.11 12.0 0.0 0.44 10.1 0.0 2.0 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 CBZ30276.1 - 0.16 11.7 0.1 0.58 9.9 0.1 1.9 1 1 1 2 2 2 0 IstB-like ATP binding protein AAA_7 PF12775.7 CBZ30276.1 - 0.17 11.4 0.0 0.48 9.9 0.0 1.7 2 0 0 2 2 2 0 P-loop containing dynein motor region COG5 PF10392.9 CBZ30278.1 - 0.016 15.4 0.2 0.042 14.0 0.2 1.7 1 0 0 1 1 1 0 Golgi transport complex subunit 5 Syntaxin PF00804.25 CBZ30278.1 - 0.026 14.2 0.1 0.05 13.3 0.1 1.4 1 0 0 1 1 1 0 Syntaxin Nup188 PF10487.9 CBZ30279.1 - 0.00064 17.8 0.0 0.0012 16.9 0.0 1.3 1 0 0 1 1 1 1 Nucleoporin subcomplex protein binding to Pom34 FXR_C1 PF16096.5 CBZ30279.1 - 1.1 9.5 3.7 0.62 10.3 0.3 2.4 2 0 0 2 2 2 0 Fragile X-related 1 protein C-terminal region 2 DUF4715 PF15835.5 CBZ30280.1 - 0.25 11.4 4.8 0.081 13.0 1.8 1.7 2 1 0 2 2 2 0 Domain of unknown function (DUF4715) DUF1664 PF07889.12 CBZ30280.1 - 0.27 11.3 8.6 1.6 8.8 1.3 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) Spc7 PF08317.11 CBZ30280.1 - 1.3 7.8 12.1 2.3 7.0 12.1 1.4 1 0 0 1 1 1 0 Spc7 kinetochore protein Atg14 PF10186.9 CBZ30280.1 - 8.4 5.4 13.9 15 4.5 13.9 1.4 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 VPS13 PF16908.5 CBZ30282.1 - 1.6e-34 119.8 0.0 4.7e-33 115.0 0.0 3.0 2 1 0 2 2 2 1 Vacuolar sorting-associated protein 13, N-terminal Chorein_N PF12624.7 CBZ30282.1 - 1.5e-27 96.1 0.0 3.5e-27 94.8 0.0 1.7 1 0 0 1 1 1 1 N-terminal region of Chorein or VPS13 SHR-BD PF06650.12 CBZ30282.1 - 4.2e-14 52.6 0.0 7.3e-11 41.9 0.0 3.1 2 1 0 2 2 2 2 SHR-binding domain of vacuolar-sorting associated protein 13 2-Hacid_dh_C PF02826.19 CBZ30283.1 - 1.5e-40 138.4 0.0 2e-40 138.0 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_2 PF03446.15 CBZ30283.1 - 1.5e-05 25.2 0.3 3.1e-05 24.2 0.1 1.6 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase IlvN PF07991.12 CBZ30283.1 - 2.7e-05 23.8 0.1 7.1e-05 22.4 0.0 1.7 2 0 0 2 2 2 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain AdoHcyase_NAD PF00670.21 CBZ30283.1 - 5.7e-05 23.2 1.0 5.7e-05 23.2 1.0 2.5 3 1 0 3 3 3 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain F420_oxidored PF03807.17 CBZ30283.1 - 0.0013 19.3 0.1 0.005 17.4 0.1 2.0 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent AlaDh_PNT_C PF01262.21 CBZ30283.1 - 0.0017 17.7 0.1 0.0029 16.9 0.1 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_7 PF13241.6 CBZ30283.1 - 0.098 13.1 0.1 0.23 11.9 0.0 1.6 2 0 0 2 2 2 0 Putative NAD(P)-binding 2-Hacid_dh PF00389.30 CBZ30283.1 - 0.12 12.1 0.0 0.18 11.5 0.0 1.4 1 1 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain Sacchrp_dh_NADP PF03435.18 CBZ30283.1 - 0.12 12.6 0.6 1 9.7 0.6 2.3 1 1 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain 2-Hacid_dh_C PF02826.19 CBZ30284.1 - 1.1e-33 116.1 0.0 1.2e-33 115.9 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_2 PF03446.15 CBZ30284.1 - 0.037 14.2 0.0 0.054 13.7 0.0 1.3 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase 2-Hacid_dh_C PF02826.19 CBZ30285.1 - 2.8e-45 153.8 0.0 3.6e-45 153.5 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_2 PF03446.15 CBZ30285.1 - 1.8e-05 24.9 0.3 4e-05 23.8 0.1 1.6 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase IlvN PF07991.12 CBZ30285.1 - 3.5e-05 23.5 0.1 9.5e-05 22.0 0.0 1.7 2 0 0 2 2 2 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain AdoHcyase_NAD PF00670.21 CBZ30285.1 - 6.8e-05 23.0 0.9 6.8e-05 23.0 0.9 2.3 3 1 0 3 3 3 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain F420_oxidored PF03807.17 CBZ30285.1 - 0.0016 19.0 0.1 0.0062 17.1 0.1 2.1 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent AlaDh_PNT_C PF01262.21 CBZ30285.1 - 0.0022 17.3 0.1 0.0037 16.6 0.1 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Transketolase_C PF02780.20 CBZ30285.1 - 0.077 12.9 0.1 1.2 9.0 0.0 2.3 2 0 0 2 2 2 0 Transketolase, C-terminal domain 2-Hacid_dh PF00389.30 CBZ30285.1 - 0.085 12.5 0.0 0.14 11.9 0.0 1.5 1 1 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_7 PF13241.6 CBZ30285.1 - 0.12 12.9 0.0 0.29 11.6 0.0 1.6 1 0 0 1 1 1 0 Putative NAD(P)-binding Sacchrp_dh_NADP PF03435.18 CBZ30285.1 - 0.17 12.1 0.6 1.2 9.4 0.6 2.2 1 1 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain DUF1143 PF06608.11 CBZ30286.1 - 0.037 14.1 0.0 0.08 13.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1143) PTEN_C2 PF10409.9 CBZ30287.1 - 2.1e-10 40.5 0.0 3.9e-10 39.6 0.0 1.5 1 0 0 1 1 1 1 C2 domain of PTEN tumour-suppressor protein DSPc PF00782.20 CBZ30287.1 - 1.7e-08 34.4 0.1 3.3e-08 33.4 0.1 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 CBZ30287.1 - 5.2e-05 22.9 0.1 0.00012 21.8 0.1 1.5 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.6 CBZ30287.1 - 0.0022 18.0 0.0 0.0046 17.0 0.0 1.5 1 0 0 1 1 1 1 Tyrosine phosphatase family PTPlike_phytase PF14566.6 CBZ30287.1 - 0.013 15.6 0.1 0.032 14.3 0.1 1.7 2 0 0 2 2 2 0 Inositol hexakisphosphate C2 PF00168.30 CBZ30288.1 - 0.042 14.1 0.0 9.7 6.6 0.0 3.4 2 1 0 2 2 2 0 C2 domain R3H-assoc PF13902.6 CBZ30289.1 - 5.3e-17 62.5 0.0 1.1e-16 61.5 0.0 1.5 1 0 0 1 1 1 1 R3H-associated N-terminal domain R3H PF01424.22 CBZ30289.1 - 0.0079 16.2 0.0 0.028 14.4 0.0 1.9 1 0 0 1 1 1 1 R3H domain PPR PF01535.20 CBZ30290.1 - 0.066 13.5 0.0 16 6.1 0.0 2.8 2 0 0 2 2 2 0 PPR repeat PPR_2 PF13041.6 CBZ30290.1 - 0.11 12.7 0.0 21 5.4 0.0 3.1 3 0 0 3 3 3 0 PPR repeat family EAP30 PF04157.16 CBZ30291.1 - 4e-65 219.4 1.1 6e-65 218.8 1.1 1.3 1 0 0 1 1 1 1 EAP30/Vps36 family HalX PF08663.10 CBZ30291.1 - 0.089 13.1 0.4 0.25 11.7 0.4 1.8 1 0 0 1 1 1 0 HalX domain DUF4189 PF13827.6 CBZ30291.1 - 0.4 11.2 2.6 0.76 10.3 0.1 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF4189) DUF3995 PF13160.6 CBZ30293.1 - 0.17 12.2 2.7 1.1 9.6 1.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3995) YueH PF14166.6 CBZ30293.1 - 0.39 10.6 1.3 3.5 7.5 0.0 2.7 3 0 0 3 3 3 0 YueH-like protein DUF3808 PF10300.9 CBZ30294.1 - 2.2e-42 145.4 0.7 3.7e-42 144.7 0.7 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3808) DUF4094 PF13334.6 CBZ30295.1 - 0.024 15.0 0.2 0.11 12.9 0.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4094) Fib_alpha PF08702.10 CBZ30295.1 - 0.078 13.2 0.8 0.14 12.3 0.2 1.8 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family p25-alpha PF05517.12 CBZ30296.1 - 4.7e-34 117.8 3.5 5.4e-34 117.6 3.5 1.0 1 0 0 1 1 1 1 p25-alpha Spo0A_C PF08769.11 CBZ30296.1 - 0.025 14.6 0.0 0.037 14.1 0.0 1.3 1 0 0 1 1 1 0 Sporulation initiation factor Spo0A C terminal SCP-1 PF05483.12 CBZ30296.1 - 0.054 11.5 0.1 0.064 11.3 0.1 1.0 1 0 0 1 1 1 0 Synaptonemal complex protein 1 (SCP-1) Kinesin PF00225.23 CBZ30297.1 - 1.2e-87 294.0 0.0 1.6e-87 293.5 0.0 1.2 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 CBZ30297.1 - 3.9e-23 82.0 0.0 6.6e-20 71.6 0.0 2.5 2 0 0 2 2 2 2 Microtubule binding TrwB_AAD_bind PF10412.9 CBZ30297.1 - 0.0092 14.9 0.8 0.027 13.4 0.0 2.0 2 0 0 2 2 2 1 Type IV secretion-system coupling protein DNA-binding domain AAA_16 PF13191.6 CBZ30297.1 - 0.075 13.4 0.2 0.35 11.2 0.0 2.3 2 0 0 2 2 2 0 AAA ATPase domain DUF4140 PF13600.6 CBZ30297.1 - 0.13 12.7 3.3 1.4 9.4 0.3 3.4 3 0 0 3 3 3 0 N-terminal domain of unknown function (DUF4140) Helicase_C PF00271.31 CBZ30298.1 - 3.3e-05 24.2 0.0 0.00019 21.8 0.0 2.4 2 1 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 CBZ30298.1 - 6.2e-05 22.8 0.0 0.00012 22.0 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_7 PF12775.7 CBZ30298.1 - 0.0049 16.4 0.0 0.01 15.4 0.0 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region ResIII PF04851.15 CBZ30298.1 - 0.034 14.2 0.0 0.07 13.1 0.0 1.5 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_30 PF13604.6 CBZ30298.1 - 0.05 13.3 0.0 0.1 12.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain UQ_con PF00179.26 CBZ30299.1 - 1.3e-22 80.0 0.0 1.5e-22 79.8 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 CBZ30299.1 - 0.058 13.1 0.0 0.14 11.8 0.0 1.7 1 1 0 1 1 1 0 Prokaryotic E2 family B Put_DNA-bind_N PF06971.13 CBZ30299.1 - 0.069 13.2 0.0 0.11 12.5 0.0 1.3 1 0 0 1 1 1 0 Putative DNA-binding protein N-terminus Amastin PF07344.11 CBZ30300.1 - 5e-47 159.6 10.6 6e-47 159.4 10.6 1.1 1 0 0 1 1 1 1 Amastin surface glycoprotein DUF805 PF05656.14 CBZ30300.1 - 0.19 12.1 9.9 0.027 14.9 5.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF805) Amastin PF07344.11 CBZ30302.1 - 6.2e-50 169.0 11.5 7.8e-50 168.7 11.5 1.1 1 0 0 1 1 1 1 Amastin surface glycoprotein Zeta_toxin PF06414.12 CBZ30303.1 - 5.8e-10 38.8 0.0 1.9e-09 37.1 0.0 1.8 1 0 0 1 1 1 1 Zeta toxin AAA_33 PF13671.6 CBZ30303.1 - 0.098 12.8 0.0 0.22 11.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain Peptidase_C15 PF01470.17 CBZ30304.1 - 5.2e-09 36.6 0.2 0.0013 18.9 0.1 2.4 2 0 0 2 2 2 2 Pyroglutamyl peptidase RCC1 PF00415.18 CBZ30306.1 - 2.7e-23 82.3 1.0 2.9e-08 34.2 0.1 4.6 4 0 0 4 4 4 4 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 CBZ30306.1 - 1.9e-18 65.8 13.2 2.8e-10 39.7 1.7 5.7 5 0 0 5 5 5 4 Regulator of chromosome condensation (RCC1) repeat TPR_12 PF13424.6 CBZ30307.1 - 0.00089 19.5 7.9 0.001 19.3 0.1 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat IQ PF00612.27 CBZ30307.1 - 0.022 14.5 1.1 0.022 14.5 1.1 7.1 6 0 0 6 6 6 0 IQ calmodulin-binding motif TPR_10 PF13374.6 CBZ30307.1 - 2.5 8.1 15.2 5.1 7.1 0.1 5.1 5 0 0 5 5 5 0 Tetratricopeptide repeat DEAD PF00270.29 CBZ30309.1 - 2.1e-45 154.6 0.0 4.5e-45 153.6 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CBZ30309.1 - 4.6e-23 81.7 0.0 1.1e-22 80.5 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DBP10CT PF08147.12 CBZ30309.1 - 2.1e-11 43.9 4.2 6.2e-11 42.4 4.2 1.8 1 0 0 1 1 1 1 DBP10CT (NUC160) domain ResIII PF04851.15 CBZ30309.1 - 0.00018 21.6 0.0 0.00045 20.3 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 CBZ30309.1 - 0.16 12.2 0.3 1.2 9.5 0.3 2.5 1 1 0 1 1 1 0 AAA domain FtsX PF02687.21 CBZ30311.1 - 1.3e-09 38.4 7.6 1.3e-09 38.4 7.6 6.4 5 1 0 5 5 5 1 FtsX-like permease family LAT PF15234.6 CBZ30312.1 - 0.013 15.3 1.5 2.3 7.9 0.2 2.5 2 0 0 2 2 2 0 Linker for activation of T-cells DUF724 PF05266.14 CBZ30312.1 - 0.06 13.2 2.3 0.16 11.8 2.3 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF724) Trypan_glycop PF00913.19 CBZ30312.1 - 0.3 10.3 4.2 0.57 9.4 4.2 1.4 1 0 0 1 1 1 0 Trypanosome variant surface glycoprotein (A-type) Mlf1IP PF10248.9 CBZ30312.1 - 0.39 10.7 3.2 0.66 9.9 2.3 1.8 2 0 0 2 2 2 0 Myelodysplasia-myeloid leukemia factor 1-interacting protein MIP-T3_C PF17749.1 CBZ30312.1 - 0.56 10.2 8.9 0.11 12.5 2.0 3.0 2 1 0 2 2 2 0 Microtubule-binding protein MIP-T3 C-terminal region Fez1 PF06818.15 CBZ30312.1 - 2.1 8.8 23.3 0.076 13.5 9.3 3.0 2 1 1 3 3 3 0 Fez1 Prefoldin_2 PF01920.20 CBZ30312.1 - 3.4 7.7 5.7 1.2 9.1 1.8 2.3 2 0 0 2 2 2 0 Prefoldin subunit Pkinase PF00069.25 CBZ30313.1 - 1.4e-56 191.8 0.0 2e-56 191.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ30313.1 - 2e-31 109.3 0.0 2.5e-31 108.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CBZ30313.1 - 0.00092 18.6 0.0 0.0013 18.1 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Orthopox_A5L PF06193.11 CBZ30313.1 - 0.0095 15.4 0.0 0.024 14.1 0.0 1.6 2 0 0 2 2 2 1 Orthopoxvirus A5L protein-like Pkinase_fungal PF17667.1 CBZ30313.1 - 0.08 11.7 0.0 0.13 11.0 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase PLDc_2 PF13091.6 CBZ30315.1 - 5.2e-30 104.1 0.0 6.6e-23 81.1 0.0 2.5 2 0 0 2 2 2 2 PLD-like domain PLDc PF00614.22 CBZ30315.1 - 8.7e-08 32.0 1.1 0.015 15.4 0.0 2.4 2 0 0 2 2 2 2 Phospholipase D Active site motif ubiquitin PF00240.23 CBZ30317.1 - 4e-16 58.5 0.0 4.5e-16 58.4 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 CBZ30317.1 - 4.5e-07 29.6 0.0 4.9e-07 29.5 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Rad60-SLD_2 PF13881.6 CBZ30317.1 - 0.00068 19.7 0.1 0.0015 18.6 0.1 1.6 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_5 PF18037.1 CBZ30317.1 - 0.0037 17.6 0.0 0.0039 17.5 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-like domain Ubiquitin_2 PF14560.6 CBZ30317.1 - 0.033 14.6 0.0 0.067 13.6 0.0 1.6 1 1 0 1 1 1 0 Ubiquitin-like domain DoxX PF07681.12 CBZ30318.1 - 0.00041 20.9 7.1 0.00041 20.9 7.1 1.6 2 0 0 2 2 2 1 DoxX DUF4239 PF14023.6 CBZ30318.1 - 0.052 13.3 2.9 0.049 13.3 1.7 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF4239) DUF202 PF02656.15 CBZ30318.1 - 0.099 13.1 2.2 1 9.9 1.0 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF202) HR_lesion PF05514.11 CBZ30318.1 - 0.21 11.8 5.3 0.51 10.5 5.3 1.7 1 1 0 1 1 1 0 HR-like lesion-inducing SIR2 PF02146.17 CBZ30319.1 - 2.2e-46 158.0 0.0 2.7e-46 157.7 0.0 1.1 1 0 0 1 1 1 1 Sir2 family TraU PF06834.11 CBZ30319.1 - 0.016 14.5 0.0 0.019 14.3 0.0 1.2 1 0 0 1 1 1 0 TraU protein Zn-ribbon_8 PF09723.10 CBZ30319.1 - 0.037 14.2 0.1 0.089 12.9 0.0 1.6 2 0 0 2 2 2 0 Zinc ribbon domain PNTB PF02233.16 CBZ30319.1 - 0.06 12.3 0.0 0.1 11.5 0.0 1.3 1 0 0 1 1 1 0 NAD(P) transhydrogenase beta subunit Pkinase PF00069.25 CBZ30320.1 - 2.3e-42 145.2 0.0 2.8e-41 141.6 0.0 2.2 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ30320.1 - 1.1e-22 80.6 0.0 7.3e-20 71.3 0.0 2.4 2 0 0 2 2 2 2 Protein tyrosine kinase Kdo PF06293.14 CBZ30320.1 - 0.07 12.5 0.0 0.14 11.5 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family OGG_N PF07934.12 CBZ30322.1 - 3e-29 101.6 0.0 5.6e-29 100.7 0.0 1.4 1 0 0 1 1 1 1 8-oxoguanine DNA glycosylase, N-terminal domain HhH-GPD PF00730.25 CBZ30322.1 - 3.4e-08 33.9 0.0 6.2e-07 29.9 0.0 2.3 1 1 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.23 CBZ30322.1 - 0.00013 21.7 0.0 0.0017 18.1 0.0 2.5 2 0 0 2 2 2 1 Helix-hairpin-helix motif Jiraiya PF15038.6 CBZ30323.1 - 0.022 14.2 0.3 0.097 12.1 0.0 2.2 2 0 0 2 2 2 0 Jiraiya DUF3382 PF11862.8 CBZ30323.1 - 0.22 11.8 2.3 2.8 8.3 0.0 3.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3382) Pkinase PF00069.25 CBZ30324.1 - 3.2e-47 161.1 0.0 8.9e-24 84.3 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ30324.1 - 2.7e-30 105.5 0.0 6.5e-17 61.7 0.0 2.5 2 1 0 2 2 2 2 Protein tyrosine kinase DSPc PF00782.20 CBZ30324.1 - 3.3e-26 91.7 0.0 6.8e-26 90.7 0.0 1.5 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain LRR_8 PF13855.6 CBZ30324.1 - 3.6e-09 36.2 10.8 4.2e-08 32.8 5.4 3.7 2 1 1 3 3 3 1 Leucine rich repeat LRR_4 PF12799.7 CBZ30324.1 - 6.3e-07 29.6 6.8 0.0069 16.8 2.8 4.1 3 1 1 4 4 4 2 Leucine Rich repeats (2 copies) Y_phosphatase PF00102.27 CBZ30324.1 - 0.001 18.7 0.0 0.0018 17.9 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase zf-UBR PF02207.20 CBZ30324.1 - 0.86 9.8 4.7 2.5 8.3 4.7 1.8 1 0 0 1 1 1 0 Putative zinc finger in N-recognin (UBR box) LRR_1 PF00560.33 CBZ30324.1 - 6.1 7.8 5.6 1.6e+02 3.5 0.2 4.6 4 0 0 4 4 4 0 Leucine Rich Repeat Thioredoxin PF00085.20 CBZ30325.1 - 1.2e-26 92.7 0.0 9.4e-26 89.8 0.0 2.2 2 0 0 2 2 2 1 Thioredoxin Thioredoxin_2 PF13098.6 CBZ30325.1 - 2.9e-08 34.1 0.4 1.2e-06 28.9 0.1 3.2 3 1 0 3 3 3 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 CBZ30325.1 - 7.4e-06 26.2 0.0 0.00045 20.5 0.0 3.3 4 0 0 4 4 4 1 Thioredoxin-like TraF PF13728.6 CBZ30325.1 - 8.2e-05 22.5 0.1 0.0011 18.9 0.0 2.6 3 0 0 3 3 3 1 F plasmid transfer operon protein Thioredoxin_6 PF13848.6 CBZ30325.1 - 0.00021 21.2 0.0 0.0048 16.8 0.0 2.5 2 0 0 2 2 2 1 Thioredoxin-like domain AhpC-TSA PF00578.21 CBZ30325.1 - 0.00038 20.4 0.0 0.0025 17.7 0.0 2.1 2 0 0 2 2 2 1 AhpC/TSA family Redoxin PF08534.10 CBZ30325.1 - 0.00098 18.9 0.1 0.0072 16.0 0.0 2.5 2 1 1 3 3 3 1 Redoxin OST3_OST6 PF04756.13 CBZ30325.1 - 0.0016 17.9 0.0 0.0034 16.8 0.0 1.6 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin_4 PF13462.6 CBZ30325.1 - 0.009 16.2 0.0 0.023 14.9 0.0 1.6 2 0 0 2 2 2 1 Thioredoxin Thioredoxin_7 PF13899.6 CBZ30325.1 - 0.015 15.5 0.0 0.04 14.1 0.0 1.8 1 0 0 1 1 1 0 Thioredoxin-like Thioredoxin_9 PF14595.6 CBZ30325.1 - 0.019 14.8 0.0 0.044 13.5 0.0 1.6 1 0 0 1 1 1 0 Thioredoxin DUF2644 PF10841.8 CBZ30325.1 - 0.16 12.2 0.1 0.55 10.5 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2644) Exo_endo_phos PF03372.23 CBZ30327.1 - 4.4e-17 62.4 0.0 1.3e-16 60.8 0.0 1.8 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Glyco_hydro_65m PF03632.15 CBZ30329.1 - 4.6e-41 141.0 0.0 6.8e-41 140.4 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 65 central catalytic domain Glyco_hydro_65C PF03633.15 CBZ30329.1 - 1.1e-10 41.2 0.1 2.3e-10 40.2 0.1 1.6 1 0 0 1 1 1 1 Glycosyl hydrolase family 65, C-terminal domain Kelch_4 PF13418.6 CBZ30330.1 - 2e-10 40.5 5.0 8.2e-05 22.5 0.0 5.1 5 0 0 5 5 5 3 Galactose oxidase, central domain Kelch_1 PF01344.25 CBZ30330.1 - 1.3e-09 37.4 9.7 2.4e-05 23.8 0.1 4.8 5 0 0 5 5 5 3 Kelch motif Kelch_5 PF13854.6 CBZ30330.1 - 7.2e-09 35.4 10.2 0.00044 20.2 0.3 5.8 6 0 0 6 6 6 3 Kelch motif Kelch_6 PF13964.6 CBZ30330.1 - 8e-08 32.3 0.3 0.024 14.9 0.0 5.0 5 0 0 5 5 5 2 Kelch motif Kelch_3 PF13415.6 CBZ30330.1 - 1.6e-07 31.5 18.9 0.00026 21.2 0.0 6.9 9 0 0 9 9 9 2 Galactose oxidase, central domain Kelch_2 PF07646.15 CBZ30330.1 - 0.041 13.9 5.1 41 4.4 0.0 5.4 5 0 0 5 5 5 0 Kelch motif HA2 PF04408.23 CBZ30331.1 - 1.1e-16 61.1 0.0 2.6e-16 59.9 0.0 1.7 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.31 CBZ30331.1 - 6.3e-12 45.8 0.0 2.7e-11 43.8 0.0 2.1 1 1 0 1 1 1 1 Helicase conserved C-terminal domain OB_NTP_bind PF07717.16 CBZ30331.1 - 1.7e-09 37.9 0.0 4.1e-09 36.7 0.0 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold DEAD PF00270.29 CBZ30331.1 - 9.6e-07 28.7 0.4 2.6e-06 27.3 0.4 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_19 PF13245.6 CBZ30331.1 - 1.4e-06 28.7 0.2 4.9e-06 26.9 0.2 1.9 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 CBZ30331.1 - 1.9e-06 28.2 0.1 6.4e-06 26.5 0.1 1.9 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 CBZ30331.1 - 2.6e-05 24.0 0.1 5.9e-05 22.9 0.1 1.5 1 0 0 1 1 1 1 AAA domain SRP54 PF00448.22 CBZ30331.1 - 5.2e-05 23.0 0.1 0.00018 21.2 0.1 1.8 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain AAA_7 PF12775.7 CBZ30331.1 - 0.0014 18.2 0.0 0.0029 17.1 0.0 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_25 PF13481.6 CBZ30331.1 - 0.0026 17.4 0.0 0.0062 16.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 CBZ30331.1 - 0.0039 16.3 0.0 0.0085 15.2 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein cobW PF02492.19 CBZ30331.1 - 0.0095 15.5 0.2 0.48 10.0 0.0 2.5 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain ResIII PF04851.15 CBZ30331.1 - 0.011 15.8 0.0 2 8.4 0.0 2.3 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit AAA PF00004.29 CBZ30331.1 - 0.017 15.5 0.0 0.095 13.1 0.0 2.3 2 1 0 2 2 1 0 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 CBZ30331.1 - 0.027 14.9 3.8 0.086 13.2 0.3 3.3 3 1 0 3 3 3 0 AAA ATPase domain AAA_29 PF13555.6 CBZ30331.1 - 0.036 13.8 0.0 0.094 12.5 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Flavi_DEAD PF07652.14 CBZ30331.1 - 0.037 14.0 0.2 0.079 12.9 0.2 1.5 1 0 0 1 1 1 0 Flavivirus DEAD domain ABC_tran PF00005.27 CBZ30331.1 - 0.055 14.0 0.0 0.15 12.5 0.0 1.9 1 1 0 1 1 1 0 ABC transporter NACHT PF05729.12 CBZ30331.1 - 0.064 13.2 0.3 0.92 9.4 0.1 3.0 2 1 0 2 2 2 0 NACHT domain AAA_11 PF13086.6 CBZ30331.1 - 0.072 12.9 0.3 0.68 9.7 0.0 2.6 2 1 1 3 3 3 0 AAA domain Helicase_RecD PF05127.14 CBZ30331.1 - 0.12 12.2 0.0 0.22 11.3 0.0 1.4 1 0 0 1 1 1 0 Helicase AAA_24 PF13479.6 CBZ30331.1 - 0.13 12.0 0.0 0.25 11.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.26 CBZ30331.1 - 0.13 11.9 0.0 0.75 9.5 0.0 2.2 2 0 0 2 2 2 0 Sigma-54 interaction domain DUF2075 PF09848.9 CBZ30331.1 - 0.17 11.1 0.0 0.3 10.3 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) ATPase PF06745.13 CBZ30331.1 - 0.21 10.9 0.0 0.46 9.8 0.0 1.5 1 0 0 1 1 1 0 KaiC Dynamin_N PF00350.23 CBZ30332.1 - 1.9e-14 54.0 0.0 1.3e-12 48.1 0.0 2.5 1 1 0 1 1 1 1 Dynamin family DUF5600 PF18150.1 CBZ30332.1 - 7.4e-12 45.8 0.0 1.6e-11 44.7 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF5600) MMR_HSR1 PF01926.23 CBZ30332.1 - 8.3e-08 32.3 0.0 2e-07 31.1 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase EHD_N PF16880.5 CBZ30332.1 - 5.3e-05 23.0 0.0 9.3e-05 22.2 0.0 1.4 1 0 0 1 1 1 1 N-terminal EH-domain containing protein GET2 PF08690.10 CBZ30332.1 - 0.55 9.9 12.7 0.82 9.3 12.7 1.3 1 0 0 1 1 1 0 GET complex subunit GET2 Peptidase_S21 PF00716.17 CBZ30332.1 - 9.8 5.8 11.6 14 5.3 11.6 1.2 1 0 0 1 1 1 0 Assemblin (Peptidase family S21) Cofilin_ADF PF00241.20 CBZ30334.1 - 7.6e-17 61.2 0.0 7.4e-11 41.9 0.0 2.2 2 0 0 2 2 2 2 Cofilin/tropomyosin-type actin-binding protein MMgT PF10270.9 CBZ30337.1 - 0.023 15.1 0.8 0.035 14.5 0.8 1.4 1 1 0 1 1 1 0 Membrane magnesium transporter Clat_adaptor_s PF01217.20 CBZ30338.1 - 4.3e-51 172.6 3.4 4.8e-51 172.4 3.4 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain tRNA-synt_2 PF00152.20 CBZ30339.1 - 1.6e-85 286.9 0.0 2.2e-85 286.5 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_synt_1c_R1 PF04558.15 CBZ30339.1 - 8.6e-34 116.9 0.1 1.4e-33 116.1 0.1 1.4 1 0 0 1 1 1 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 tRNA_anti-codon PF01336.25 CBZ30339.1 - 8.4e-11 41.7 0.0 1.8e-10 40.6 0.0 1.6 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain VGCC_alpha2 PF08473.11 CBZ30340.1 - 0.012 14.4 0.9 0.03 13.1 0.2 1.8 1 1 1 2 2 2 0 Neuronal voltage-dependent calcium channel alpha 2acd zf-UDP PF14569.6 CBZ30340.1 - 0.022 14.9 0.0 0.055 13.6 0.0 1.7 1 0 0 1 1 1 0 Zinc-binding RING-finger DUF2046 PF09755.9 CBZ30341.1 - 5.7e-06 25.8 21.5 5.7e-06 25.8 21.5 2.5 2 1 0 2 2 2 1 Uncharacterized conserved protein H4 (DUF2046) MscS_porin PF12795.7 CBZ30341.1 - 0.00018 21.1 25.0 0.013 15.1 2.2 2.2 2 0 0 2 2 2 2 Mechanosensitive ion channel porin domain TMPIT PF07851.13 CBZ30341.1 - 0.00063 19.1 14.2 0.083 12.1 5.5 2.3 2 0 0 2 2 2 2 TMPIT-like protein TrmB PF01978.19 CBZ30341.1 - 0.015 15.2 1.4 0.067 13.1 0.7 2.4 3 0 0 3 3 3 0 Sugar-specific transcriptional regulator TrmB Chi-conotoxin PF16981.5 CBZ30341.1 - 0.14 12.4 0.1 0.58 10.4 0.1 2.1 1 0 0 1 1 1 0 chi-Conotoxin or t superfamily Atg14 PF10186.9 CBZ30341.1 - 0.43 9.6 19.8 0.97 8.5 11.3 2.1 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 Exonuc_VII_L PF02601.15 CBZ30341.1 - 0.5 9.9 20.3 0.3 10.6 11.2 2.1 2 0 0 2 2 2 0 Exonuclease VII, large subunit DUF4680 PF15730.5 CBZ30341.1 - 0.51 10.7 5.0 2 8.8 4.3 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF4680) AAA_13 PF13166.6 CBZ30341.1 - 6.3 5.3 13.0 3.2 6.3 7.6 2.1 2 0 0 2 2 2 0 AAA domain PRKCSH-like PF12999.7 CBZ30341.1 - 7.6 6.3 5.3 10 5.9 4.1 1.8 1 1 0 1 1 1 0 Glucosidase II beta subunit-like Spc7 PF08317.11 CBZ30341.1 - 8.2 5.2 28.4 4.9 5.9 17.4 2.3 2 1 0 2 2 2 0 Spc7 kinetochore protein CBFD_NFYB_HMF PF00808.23 CBZ30342.1 - 9.2e-06 25.9 0.2 1.7e-05 25.0 0.2 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 CBZ30342.1 - 0.00031 21.1 0.5 0.00062 20.1 0.5 1.5 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-X PF09415.10 CBZ30342.1 - 0.19 12.1 0.3 0.44 10.9 0.3 1.6 1 0 0 1 1 1 0 CENP-S associating Centromere protein X EF-hand_7 PF13499.6 CBZ30344.1 - 1.7e-23 82.8 5.6 2.1e-15 56.9 1.1 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 CBZ30344.1 - 4.3e-21 72.8 9.9 1.8e-07 30.2 1.4 3.5 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.6 CBZ30344.1 - 4.1e-19 66.8 3.5 3.5e-06 26.5 0.1 3.5 3 0 0 3 3 3 3 EF-hand domain EF-hand_8 PF13833.6 CBZ30344.1 - 1.8e-14 53.3 8.5 1.9e-11 43.6 0.9 3.3 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_9 PF14658.6 CBZ30344.1 - 2.4e-13 50.2 0.3 1.4e-06 28.6 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 CBZ30344.1 - 1.5e-12 46.4 4.9 0.00032 20.1 1.0 3.5 3 0 0 3 3 3 3 EF hand EF-hand_4 PF12763.7 CBZ30344.1 - 1.1e-06 28.6 0.5 0.0048 16.8 0.2 2.2 2 0 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand Caleosin PF05042.13 CBZ30344.1 - 0.00089 19.2 0.1 0.32 10.9 0.0 3.0 2 1 1 3 3 3 1 Caleosin related protein DUF3164 PF11363.8 CBZ30344.1 - 0.0058 16.3 0.2 0.072 12.7 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF3164) EF-hand_14 PF17959.1 CBZ30344.1 - 0.0078 16.5 3.2 0.35 11.3 0.3 2.3 1 1 1 2 2 2 1 EF-hand domain TerB PF05099.13 CBZ30344.1 - 0.013 15.5 5.6 0.1 12.6 1.2 2.5 1 1 2 3 3 3 0 Tellurite resistance protein TerB MgtE_N PF03448.17 CBZ30344.1 - 0.033 14.8 0.6 0.033 14.8 0.6 2.5 3 0 0 3 3 3 0 MgtE intracellular N domain SPARC_Ca_bdg PF10591.9 CBZ30344.1 - 0.068 13.5 1.7 1.2 9.5 0.4 2.2 1 1 1 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region Dockerin_1 PF00404.18 CBZ30344.1 - 0.082 13.1 0.0 0.21 11.8 0.0 1.7 1 0 0 1 1 1 0 Dockerin type I domain SurA_N_2 PF13623.6 CBZ30344.1 - 0.086 12.7 4.6 0.96 9.3 0.4 2.4 1 1 1 2 2 2 0 SurA N-terminal domain EF-hand_11 PF08976.11 CBZ30344.1 - 0.11 13.3 0.4 0.43 11.5 0.1 1.9 2 0 0 2 2 2 0 EF-hand domain DUF3911 PF13050.6 CBZ30344.1 - 0.53 10.4 3.2 2.7 8.1 0.2 3.0 3 1 0 3 3 3 0 Protein of unknown function (DUF3911) DUF1091 PF06477.13 CBZ30345.1 - 0.097 13.2 0.1 24 5.5 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF1091) Aminotran_4 PF01063.19 CBZ30346.1 - 1.1e-36 126.8 0.0 1.4e-36 126.4 0.0 1.1 1 0 0 1 1 1 1 Amino-transferase class IV Glycos_transf_1 PF00534.20 CBZ30347.1 - 5.8e-28 97.6 0.0 1e-27 96.8 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 CBZ30347.1 - 3.6e-14 53.3 0.1 6.4e-13 49.3 0.0 2.2 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 CBZ30347.1 - 4.3e-05 23.6 0.0 7e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_1_2 PF13524.6 CBZ30347.1 - 0.002 18.5 0.0 0.0054 17.1 0.0 1.8 1 1 0 1 1 1 1 Glycosyl transferases group 1 DnaJ PF00226.31 CBZ30348.1 - 2e-19 69.5 0.1 5.4e-19 68.1 0.1 1.8 1 0 0 1 1 1 1 DnaJ domain TPR_1 PF00515.28 CBZ30348.1 - 9.5e-18 63.2 14.5 1.5e-05 24.6 0.1 6.0 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_2 PF07719.17 CBZ30348.1 - 1.8e-14 52.6 24.8 0.00051 20.0 0.3 7.5 8 0 0 8 8 7 4 Tetratricopeptide repeat TPR_8 PF13181.6 CBZ30348.1 - 3.9e-08 32.9 14.5 0.011 15.9 0.1 6.8 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_16 PF13432.6 CBZ30348.1 - 4.3e-06 27.3 11.3 0.65 10.7 0.2 5.9 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_12 PF13424.6 CBZ30348.1 - 2.8e-05 24.3 0.7 2.8e-05 24.3 0.7 5.2 5 1 0 5 5 5 1 Tetratricopeptide repeat TPR_17 PF13431.6 CBZ30348.1 - 0.0001 22.4 0.2 7.6 7.2 0.0 5.3 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_11 PF13414.6 CBZ30348.1 - 0.00014 21.4 1.0 1 9.1 0.3 4.3 4 0 0 4 4 4 1 TPR repeat Rapsyn_N PF10579.9 CBZ30348.1 - 0.00073 19.6 0.7 0.068 13.3 0.0 3.2 2 1 1 3 3 3 1 Rapsyn N-terminal myristoylation and linker region Strep_SA_rep PF06696.11 CBZ30348.1 - 0.011 15.7 0.2 0.2 11.7 0.1 2.8 2 0 0 2 2 2 0 Streptococcal surface antigen repeat TPR_19 PF14559.6 CBZ30348.1 - 0.025 15.1 8.2 24 5.5 0.1 5.7 3 3 4 7 7 6 0 Tetratricopeptide repeat TPR_7 PF13176.6 CBZ30348.1 - 0.044 13.8 10.7 3.9 7.7 0.1 5.6 5 1 1 6 6 5 0 Tetratricopeptide repeat TPR_6 PF13174.6 CBZ30348.1 - 0.1 13.3 11.6 2.5 8.9 0.0 6.4 8 0 0 8 8 7 0 Tetratricopeptide repeat TPR_9 PF13371.6 CBZ30348.1 - 0.17 12.0 6.4 1.1 9.4 0.6 3.9 3 1 1 4 4 4 0 Tetratricopeptide repeat Syntaxin_2 PF14523.6 CBZ30348.1 - 0.18 12.2 0.0 21 5.5 0.0 2.5 2 0 0 2 2 2 0 Syntaxin-like protein ANAPC3 PF12895.7 CBZ30348.1 - 1.2 9.4 15.3 0.66 10.2 0.5 4.7 5 1 1 6 6 5 0 Anaphase-promoting complex, cyclosome, subunit 3 Troponin PF00992.20 CBZ30348.1 - 2.5 8.4 7.6 2.9 8.2 0.0 3.1 3 1 0 3 3 3 0 Troponin TPR_10 PF13374.6 CBZ30348.1 - 5.1 7.1 9.5 3.8 7.5 0.1 4.8 6 0 0 6 6 6 0 Tetratricopeptide repeat Sec7 PF01369.20 CBZ30350.1 - 2.4e-47 161.0 0.0 3.6e-47 160.4 0.0 1.3 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.7 CBZ30350.1 - 2.5e-06 27.5 0.0 1e-05 25.5 0.0 2.1 1 0 0 1 1 1 1 Guanine nucleotide exchange factor in Golgi transport N-terminal GTP_EFTU PF00009.27 CBZ30351.1 - 5.8e-07 29.2 0.0 1.9e-06 27.6 0.0 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 CBZ30351.1 - 0.007 16.3 0.1 0.87 9.5 0.1 2.3 2 0 0 2 2 2 1 RsgA GTPase ATP_bind_1 PF03029.17 CBZ30351.1 - 0.036 13.9 1.2 2.3 8.0 0.1 2.2 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein ABC_tran PF00005.27 CBZ30351.1 - 0.068 13.7 0.0 0.18 12.3 0.0 1.6 1 0 0 1 1 1 0 ABC transporter AAA_29 PF13555.6 CBZ30351.1 - 0.088 12.6 0.2 0.22 11.3 0.2 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain GTP_EFTU_D2 PF03144.25 CBZ30351.1 - 0.12 12.7 0.1 0.32 11.4 0.1 1.7 1 0 0 1 1 1 0 Elongation factor Tu domain 2 Ribosomal_L35Ae PF01247.18 CBZ30352.1 - 2.7e-33 114.0 0.8 4.3e-33 113.3 0.8 1.3 1 0 0 1 1 1 1 Ribosomal protein L35Ae RimM PF01782.18 CBZ30352.1 - 4.9e-05 23.5 0.7 0.12 12.7 0.1 2.5 2 1 0 2 2 2 2 RimM N-terminal domain MFS_MOT1 PF16983.5 CBZ30354.1 - 0.16 12.3 2.0 0.44 11.0 2.0 1.7 1 1 0 1 1 1 0 Molybdate transporter of MFS superfamily CENP-F_leu_zip PF10473.9 CBZ30356.1 - 0.00048 20.2 16.8 0.00048 20.2 16.8 8.8 2 2 7 9 9 9 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 PriCT_1 PF08708.11 CBZ30356.1 - 0.057 13.2 0.1 2.1 8.2 0.0 3.2 2 0 0 2 2 2 0 Primase C terminal 1 (PriCT-1) TrmB PF01978.19 CBZ30356.1 - 0.089 12.7 0.1 2.8 7.9 0.0 3.1 3 0 0 3 3 3 0 Sugar-specific transcriptional regulator TrmB LRR_6 PF13516.6 CBZ30357.1 - 1.6e-06 27.7 2.9 0.12 12.5 0.0 4.3 5 0 0 5 5 5 3 Leucine Rich repeat BRX PF08381.11 CBZ30357.1 - 0.055 12.8 0.0 0.13 11.7 0.0 1.5 1 0 0 1 1 1 0 Transcription factor regulating root and shoot growth via Pin3 ANAPC4_WD40 PF12894.7 CBZ30358.1 - 6.8e-05 23.1 0.0 2.3 8.6 0.0 4.0 4 0 0 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 CBZ30358.1 - 0.028 15.3 1.8 22 6.1 0.0 3.9 3 0 0 3 3 3 0 WD domain, G-beta repeat Epiglycanin_C PF14654.6 CBZ30358.1 - 0.034 14.2 0.1 0.034 14.2 0.1 2.6 3 0 0 3 3 3 0 Mucin, catalytic, TM and cytoplasmic tail region DHHA1 PF02272.19 CBZ30358.1 - 6.7 7.1 6.0 18 5.7 3.1 2.3 2 0 0 2 2 2 0 DHHA1 domain PP2C PF00481.21 CBZ30359.1 - 7.4e-52 176.5 0.0 1e-51 176.1 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 CBZ30359.1 - 0.0002 21.1 0.2 0.00046 19.9 0.2 1.7 1 1 0 1 1 1 1 Protein phosphatase 2C PP2C PF00481.21 CBZ30360.1 - 2.3e-53 181.5 0.0 2.8e-53 181.2 0.0 1.0 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 CBZ30360.1 - 0.0087 15.7 0.0 0.018 14.7 0.0 1.6 1 1 0 1 1 1 1 Protein phosphatase 2C Sec7 PF01369.20 CBZ30362.1 - 7.3e-47 159.4 0.0 5e-45 153.4 0.0 2.9 3 0 0 3 3 3 1 Sec7 domain Sec7_N PF12783.7 CBZ30362.1 - 3.5e-19 69.3 1.7 7.3e-19 68.2 0.2 2.4 2 0 0 2 2 2 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1981 PF09324.10 CBZ30362.1 - 8.9e-18 63.9 0.0 2.2e-17 62.6 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1981) Ribosomal_S20p PF01649.18 CBZ30362.1 - 0.3 11.7 0.8 2.6 8.8 0.4 2.5 2 0 0 2 2 2 0 Ribosomal protein S20 Lebercilin PF15619.6 CBZ30364.1 - 0.00036 20.2 18.1 0.00036 20.2 18.1 6.7 5 1 0 5 5 5 1 Ciliary protein causing Leber congenital amaurosis disease C2 PF00168.30 CBZ30364.1 - 0.0015 18.8 0.0 0.0039 17.4 0.0 1.7 1 0 0 1 1 1 1 C2 domain Shugoshin_N PF07558.11 CBZ30364.1 - 0.0026 17.6 28.1 0.053 13.4 0.4 7.8 7 0 0 7 7 7 3 Shugoshin N-terminal coiled-coil region Fez1 PF06818.15 CBZ30364.1 - 0.017 15.6 71.9 0.27 11.7 4.0 5.1 2 1 2 4 4 4 0 Fez1 DUF3573 PF12097.8 CBZ30364.1 - 1.6 7.5 3.7 6.8 5.4 0.1 3.2 2 2 0 2 2 2 0 Protein of unknown function (DUF3573) HC2 PF07382.11 CBZ30364.1 - 2.3 8.3 6.1 9.3 6.3 0.5 2.2 2 0 0 2 2 2 0 Histone H1-like nucleoprotein HC2 IFT57 PF10498.9 CBZ30365.1 - 5.2e-05 22.4 1.5 5.2e-05 22.4 1.5 1.7 2 0 0 2 2 2 1 Intra-flagellar transport protein 57 DUF4706 PF15797.5 CBZ30365.1 - 0.0045 17.5 0.3 4.5 7.8 0.1 2.8 2 0 0 2 2 2 2 Domain of unknown function (DUF4706) Tmemb_cc2 PF10267.9 CBZ30365.1 - 0.0047 16.1 3.9 0.0047 16.1 3.9 2.4 2 1 0 2 2 2 1 Predicted transmembrane and coiled-coil 2 protein OmpH PF03938.14 CBZ30365.1 - 0.1 12.9 17.3 0.39 11.1 5.6 3.2 3 0 0 3 3 3 0 Outer membrane protein (OmpH-like) HsbA PF12296.8 CBZ30365.1 - 0.16 12.4 2.7 0.56 10.6 2.0 2.1 2 0 0 2 2 2 0 Hydrophobic surface binding protein A AAA_23 PF13476.6 CBZ30365.1 - 0.3 11.6 0.0 0.3 11.6 0.0 2.2 3 0 0 3 3 3 0 AAA domain UPF0242 PF06785.11 CBZ30365.1 - 0.44 10.6 13.1 0.25 11.4 2.3 3.1 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0242) N-terminus Spc7 PF08317.11 CBZ30365.1 - 0.5 9.2 15.8 2.5 6.9 4.7 3.1 3 0 0 3 3 3 0 Spc7 kinetochore protein RecG_N PF17190.4 CBZ30365.1 - 2.2 9.1 6.8 5.5 7.8 0.4 2.9 2 0 0 2 2 2 0 RecG N-terminal helical domain ERM PF00769.19 CBZ30365.1 - 5.5 6.7 16.6 0.18 11.6 3.2 3.1 3 0 0 3 3 3 0 Ezrin/radixin/moesin family DUF3510 PF12022.8 CBZ30366.1 - 2.1e-05 24.9 24.9 28 5.1 0.1 9.4 10 1 0 10 10 10 7 Domain of unknown function (DUF3510) Spc7 PF08317.11 CBZ30366.1 - 0.00073 18.5 126.2 0.55 9.1 6.6 11.1 2 2 10 12 12 12 10 Spc7 kinetochore protein HTHP PF11534.8 CBZ30366.1 - 0.029 14.8 43.8 28 5.2 0.3 9.5 9 0 0 9 9 9 0 Hexameric tyrosine-coordinated heme protein (HTHP) Corona_S2 PF01601.16 CBZ30367.1 - 0.04 12.4 0.2 0.072 11.6 0.2 1.4 1 0 0 1 1 1 0 Coronavirus S2 glycoprotein Tfb5 PF06331.12 CBZ30367.1 - 0.17 11.9 3.5 7.1 6.7 0.0 3.8 3 0 0 3 3 3 0 Transcription factor TFIIH complex subunit Tfb5 DUF3800 PF12686.7 CBZ30367.1 - 0.55 10.9 3.6 12 6.6 3.8 2.9 1 1 0 1 1 1 0 Protein of unknown function (DUF3800) PKcGMP_CC PF16808.5 CBZ30367.1 - 4.7 7.1 19.6 3.7 7.5 6.8 3.3 2 0 0 2 2 2 0 Coiled-coil N-terminus of cGMP-dependent protein kinase HetR_C PF18460.1 CBZ30367.1 - 6.6 6.7 10.9 0.29 11.1 0.5 3.8 4 1 1 5 5 5 0 Heterocyst differentiation regulator C-terminal Hood domain FUSC PF04632.12 CBZ30367.1 - 9.7 4.6 33.6 0.18 10.3 7.1 3.1 2 1 1 3 3 3 0 Fusaric acid resistance protein family Alba PF01918.21 CBZ30368.1 - 3.4e-17 62.0 0.3 4.9e-17 61.5 0.3 1.2 1 0 0 1 1 1 1 Alba Rpp20 PF12328.8 CBZ30368.1 - 0.0051 16.8 0.1 0.0077 16.2 0.1 1.4 1 1 0 1 1 1 1 Rpp20 subunit of nuclear RNase MRP and P Adap_comp_sub PF00928.21 CBZ30369.1 - 9e-58 195.7 0.0 1.1e-57 195.4 0.0 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 CBZ30369.1 - 0.0026 17.7 0.0 0.0041 17.1 0.0 1.4 1 0 0 1 1 1 1 Clathrin adaptor complex small chain ACBP PF00887.19 CBZ30370.1 - 1.1e-15 57.6 1.8 1.2e-15 57.5 1.8 1.0 1 0 0 1 1 1 1 Acyl CoA binding protein PhdYeFM_antitox PF02604.19 CBZ30370.1 - 0.17 11.7 0.4 18 5.2 0.1 2.1 2 0 0 2 2 2 0 Antitoxin Phd_YefM, type II toxin-antitoxin system TIP49 PF06068.13 CBZ30371.1 - 3.5e-157 523.1 0.6 3.5e-157 523.1 0.6 1.7 2 0 0 2 2 2 1 TIP49 P-loop domain TIP49_C PF17856.1 CBZ30371.1 - 1.4e-24 86.0 1.9 2e-24 85.5 0.7 2.0 2 0 0 2 2 1 1 TIP49 AAA-lid domain AAA PF00004.29 CBZ30371.1 - 1.1e-07 32.3 2.0 7.2e-05 23.2 0.1 3.1 3 1 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 CBZ30371.1 - 7.5e-07 29.0 0.5 0.00067 19.4 0.1 2.8 3 0 0 3 3 3 2 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 CBZ30371.1 - 1.7e-05 24.8 0.2 0.0039 17.2 0.0 3.1 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) DnaB_C PF03796.15 CBZ30371.1 - 1.8e-05 24.2 0.2 3.7e-05 23.2 0.2 1.5 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain Mg_chelatase PF01078.21 CBZ30371.1 - 8e-05 22.1 1.2 0.0016 17.9 0.6 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_16 PF13191.6 CBZ30371.1 - 0.00012 22.6 0.1 0.00061 20.2 0.1 2.1 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 CBZ30371.1 - 0.00016 22.0 1.1 0.15 12.3 0.0 2.9 2 1 0 3 3 3 2 AAA domain AAA_19 PF13245.6 CBZ30371.1 - 0.0002 21.7 6.0 0.00079 19.8 1.7 3.0 2 1 0 2 2 2 1 AAA domain NACHT PF05729.12 CBZ30371.1 - 0.0093 15.9 0.1 0.03 14.2 0.0 1.8 2 0 0 2 2 2 1 NACHT domain AAA_17 PF13207.6 CBZ30371.1 - 0.011 16.1 0.2 0.1 13.0 0.1 2.5 2 1 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 CBZ30371.1 - 0.013 14.8 0.5 0.03 13.6 0.5 1.6 1 0 0 1 1 1 0 Zeta toxin Sigma54_activat PF00158.26 CBZ30371.1 - 0.016 14.9 0.1 6.7 6.4 0.1 2.6 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_25 PF13481.6 CBZ30371.1 - 0.035 13.7 0.2 0.12 12.0 0.2 1.8 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 CBZ30371.1 - 0.038 14.0 0.2 0.11 12.4 0.2 1.8 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE CPT PF07931.12 CBZ30371.1 - 0.046 13.6 0.5 0.18 11.6 0.2 2.3 2 1 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein AAA_28 PF13521.6 CBZ30371.1 - 0.047 13.9 0.1 0.11 12.7 0.1 1.6 1 0 0 1 1 1 0 AAA domain TFIID-31kDa PF02291.15 CBZ30371.1 - 0.06 13.4 0.1 0.11 12.6 0.1 1.4 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit AAA_33 PF13671.6 CBZ30371.1 - 0.064 13.4 0.0 0.15 12.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain GATase PF00117.28 CBZ30371.1 - 0.079 12.7 0.2 0.84 9.4 0.0 2.1 2 0 0 2 2 2 0 Glutamine amidotransferase class-I AAA_7 PF12775.7 CBZ30371.1 - 0.1 12.1 0.6 0.44 10.0 0.1 2.3 3 0 0 3 3 3 0 P-loop containing dynein motor region ATPase PF06745.13 CBZ30371.1 - 0.13 11.6 4.1 0.052 12.9 1.1 1.9 2 1 0 2 2 2 0 KaiC Suv3_C_1 PF18147.1 CBZ30372.1 - 3.1e-09 36.6 0.2 1.3e-08 34.6 0.2 2.1 2 0 0 2 2 2 1 Suv3 C-terminal domain 1 SUV3_C PF12513.8 CBZ30372.1 - 7.9e-09 35.3 0.1 1.6e-08 34.3 0.1 1.6 1 0 0 1 1 1 1 Mitochondrial degradasome RNA helicase subunit C terminal Helicase_C PF00271.31 CBZ30372.1 - 1.3e-05 25.5 0.0 5.3e-05 23.5 0.0 1.9 1 1 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 CBZ30372.1 - 0.0074 16.1 0.0 0.035 13.9 0.0 2.1 1 1 1 2 2 2 1 DEAD/DEAH box helicase Kinesin PF00225.23 CBZ30372.1 - 0.065 12.2 0.0 0.1 11.5 0.0 1.2 1 0 0 1 1 1 0 Kinesin motor domain PhoLip_ATPase_C PF16212.5 CBZ30373.1 - 6.2e-44 150.6 23.8 6.2e-44 150.6 23.8 2.1 2 0 0 2 2 2 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 CBZ30373.1 - 5.2e-23 80.5 0.2 1.3e-22 79.2 0.2 1.7 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Hydrolase PF00702.26 CBZ30373.1 - 1.6e-12 48.2 0.1 1.2e-05 25.7 0.0 3.2 3 0 0 3 3 3 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 CBZ30373.1 - 1.2e-08 34.9 0.0 4.1e-07 30.0 0.0 2.4 2 0 0 2 2 2 1 Cation transport ATPase (P-type) E1-E2_ATPase PF00122.20 CBZ30373.1 - 0.00022 20.8 0.1 0.0027 17.3 0.0 2.6 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase_3 PF08282.12 CBZ30373.1 - 0.0021 17.9 0.0 0.004 16.9 0.0 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 CBZ30373.1 - 0.036 14.5 0.1 11 6.4 0.0 2.7 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase Castor_Poll_mid PF06241.12 CBZ30373.1 - 0.15 12.0 0.0 0.34 10.9 0.0 1.5 1 0 0 1 1 1 0 Castor and Pollux, part of voltage-gated ion channel DUF21 PF01595.20 CBZ30375.1 - 4.6e-33 114.4 0.2 4.6e-33 114.4 0.2 2.2 2 0 0 2 2 2 1 Cyclin M transmembrane N-terminal domain CBS PF00571.28 CBZ30375.1 - 6.1e-06 26.6 0.1 0.017 15.6 0.1 2.5 2 0 0 2 2 2 2 CBS domain cNMP_binding PF00027.29 CBZ30375.1 - 0.012 15.7 0.0 0.027 14.5 0.0 1.6 1 0 0 1 1 1 0 Cyclic nucleotide-binding domain MHYT PF03707.16 CBZ30375.1 - 2.4 8.4 8.3 3.1 8.0 0.9 2.6 2 0 0 2 2 2 0 Bacterial signalling protein N terminal repeat Vps52 PF04129.12 CBZ30376.1 - 1.7e-16 60.0 2.4 3e-15 56.0 1.9 2.1 2 0 0 2 2 2 1 Vps52 / Sac2 family TMCO5 PF14992.6 CBZ30376.1 - 0.038 13.6 1.0 0.059 12.9 0.4 1.5 1 1 0 1 1 1 0 TMCO5 family XOO_2897-deam PF14440.6 CBZ30376.1 - 0.073 13.2 0.0 17 5.6 0.0 2.8 2 0 0 2 2 2 0 Xanthomonas XOO_2897-like deaminase CENP-H PF05837.12 CBZ30376.1 - 0.099 13.1 0.3 0.37 11.2 0.3 2.0 1 0 0 1 1 1 0 Centromere protein H (CENP-H) FAD_binding_1 PF00667.20 CBZ30377.1 - 2.9e-31 108.8 0.0 4.1e-31 108.3 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.25 CBZ30377.1 - 2.8e-23 82.7 0.0 6.3e-23 81.6 0.0 1.6 2 0 0 2 2 2 1 Flavodoxin NAD_binding_1 PF00175.21 CBZ30377.1 - 1.6e-15 57.7 0.0 3.2e-15 56.7 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain WD40 PF00400.32 CBZ30378.1 - 7.3e-14 51.9 5.2 0.0017 19.2 0.2 6.5 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBZ30378.1 - 7.6e-08 32.6 0.2 7.2e-05 23.0 0.1 2.9 2 0 0 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain R_equi_Vir PF05526.11 CBZ30378.1 - 0.047 13.5 0.5 5.5 6.8 0.0 3.1 3 0 0 3 3 3 0 Rhodococcus equi virulence-associated protein RRM_1 PF00076.22 CBZ30380.1 - 1.1e-11 44.3 0.0 2.5e-11 43.2 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) eIF3g PF12353.8 CBZ30380.1 - 0.0011 19.3 0.6 0.0041 17.5 0.0 2.0 1 1 1 2 2 2 1 Eukaryotic translation initiation factor 3 subunit G zf-PHD-like PF15446.6 CBZ30381.1 - 0.09 12.4 0.0 0.2 11.3 0.0 1.5 1 0 0 1 1 1 0 PHD/FYVE-zinc-finger like domain MFS_1 PF07690.16 CBZ30382.1 - 4.3e-24 85.1 23.8 2.6e-12 46.4 10.5 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily Methyltransf_11 PF08241.12 CBZ30385.1 - 3e-09 37.4 0.0 0.0017 19.0 0.0 2.3 2 0 0 2 2 2 2 Methyltransferase domain WBS_methylT PF12589.8 CBZ30385.1 - 8.5e-09 36.1 9.7 2.4e-08 34.6 9.7 1.8 1 0 0 1 1 1 1 Methyltransferase involved in Williams-Beuren syndrome Methyltransf_25 PF13649.6 CBZ30385.1 - 2.6e-08 34.5 0.0 0.00018 22.1 0.0 2.4 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_31 PF13847.6 CBZ30385.1 - 0.00011 22.0 0.0 0.0034 17.2 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 CBZ30385.1 - 0.00015 22.5 0.0 0.018 15.8 0.0 2.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 CBZ30385.1 - 0.00066 19.5 0.0 0.00091 19.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain NOA36 PF06524.12 CBZ30385.1 - 3.6 6.8 12.1 0.14 11.4 0.4 2.6 3 0 0 3 3 3 0 NOA36 protein CDC45 PF02724.14 CBZ30385.1 - 4.7 5.4 17.1 0.46 8.7 8.2 2.0 2 0 0 2 2 2 0 CDC45-like protein FAM176 PF14851.6 CBZ30386.1 - 0.21 11.3 7.5 1.1 8.9 0.1 2.3 2 0 0 2 2 2 0 FAM176 family CDC45 PF02724.14 CBZ30386.1 - 0.22 9.8 4.8 0.38 9.0 0.0 2.0 2 0 0 2 2 2 0 CDC45-like protein FYDLN_acid PF09538.10 CBZ30386.1 - 5.2 7.8 14.0 11 6.8 0.6 2.5 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) MscS_TM PF12794.7 CBZ30386.1 - 7.6 5.3 6.1 14 4.4 6.1 1.5 1 0 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 Metallophos PF00149.28 CBZ30388.1 - 8.1e-15 55.9 0.0 3.8e-09 37.4 0.0 3.4 3 1 0 3 3 3 3 Calcineurin-like phosphoesterase Ribosomal_S19e PF01090.19 CBZ30389.1 - 5.6e-43 145.9 0.0 7e-43 145.6 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S19e Mrr_N PF14338.6 CBZ30389.1 - 0.0098 16.0 0.0 0.016 15.3 0.0 1.4 1 0 0 1 1 1 1 Mrr N-terminal domain SRP68 PF16969.5 CBZ30390.1 - 5.1e-54 184.2 12.2 3.1e-51 175.0 12.2 2.9 1 1 0 1 1 1 1 RNA-binding signal recognition particle 68 Terpene_synth_C PF03936.16 CBZ30390.1 - 0.016 14.5 0.2 0.061 12.7 0.0 1.9 2 0 0 2 2 2 0 Terpene synthase family, metal binding domain SRP54 PF00448.22 CBZ30390.1 - 0.087 12.4 0.1 0.98 9.0 0.0 2.2 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain PriC PF07445.12 CBZ30390.1 - 0.14 12.1 4.4 0.32 10.9 0.5 2.7 2 1 0 2 2 2 0 Primosomal replication protein priC TPR_12 PF13424.6 CBZ30390.1 - 0.8 10.0 5.0 0.29 11.5 0.3 2.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.17 CBZ30390.1 - 4 7.8 8.5 0.17 12.1 0.4 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat AAA_16 PF13191.6 CBZ30391.1 - 3.4e-07 30.8 2.5 4e-07 30.6 0.1 2.3 3 0 0 3 3 3 1 AAA ATPase domain AAA_22 PF13401.6 CBZ30391.1 - 8.9e-05 22.8 0.6 0.00032 21.0 0.0 2.2 2 1 0 2 2 2 1 AAA domain DUF2760 PF10816.8 CBZ30391.1 - 0.011 15.6 0.1 2.5 7.9 0.0 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF2760) AAA_18 PF13238.6 CBZ30391.1 - 0.013 16.1 0.0 0.039 14.5 0.0 1.8 1 0 0 1 1 1 0 AAA domain Viral_helicase1 PF01443.18 CBZ30391.1 - 0.043 13.5 1.6 0.059 13.1 0.0 2.0 2 1 0 2 2 2 0 Viral (Superfamily 1) RNA helicase AAA_33 PF13671.6 CBZ30391.1 - 0.054 13.7 2.1 0.27 11.4 0.0 2.8 2 1 1 3 3 3 0 AAA domain AAA_14 PF13173.6 CBZ30391.1 - 0.081 13.0 0.0 0.19 11.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 CBZ30391.1 - 0.11 12.4 0.0 0.19 11.6 0.0 1.4 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea Adeno_IVa2 PF02456.15 CBZ30391.1 - 0.12 11.1 0.0 0.19 10.5 0.0 1.2 1 0 0 1 1 1 0 Adenovirus IVa2 protein eIF-1a PF01176.19 CBZ30391.1 - 0.16 11.8 1.4 12 5.8 0.1 2.9 3 0 0 3 3 3 0 Translation initiation factor 1A / IF-1 DUF892 PF05974.12 CBZ30391.1 - 0.31 11.0 2.9 3 7.8 0.3 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF892) Peptidase_M14 PF00246.24 CBZ30392.1 - 2.4e-17 63.7 0.0 1e-16 61.6 0.0 2.0 1 1 0 1 1 1 1 Zinc carboxypeptidase Pepdidase_M14_N PF18027.1 CBZ30392.1 - 8.8e-07 29.3 0.1 2.1e-06 28.0 0.1 1.6 1 0 0 1 1 1 1 Cytosolic carboxypeptidase N-terminal domain AstE_AspA PF04952.14 CBZ30392.1 - 8.2e-05 21.8 0.1 0.00013 21.2 0.1 1.3 1 0 0 1 1 1 1 Succinylglutamate desuccinylase / Aspartoacylase family PIN_11 PF18479.1 CBZ30392.1 - 0.044 13.9 0.0 0.091 12.9 0.0 1.4 1 0 0 1 1 1 0 PIN like domain VioE PF18234.1 CBZ30392.1 - 0.12 12.5 0.1 0.3 11.2 0.0 1.6 2 0 0 2 2 2 0 Violacein biosynthetic enzyme VioE cNMP_binding PF00027.29 CBZ30393.1 - 1.9e-24 85.5 0.6 1.8e-11 43.9 0.1 2.5 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain Cupin_2 PF07883.11 CBZ30393.1 - 0.0027 17.4 0.6 0.011 15.4 0.1 2.2 2 0 0 2 2 2 1 Cupin domain DUF2742 PF10888.8 CBZ30393.1 - 0.17 12.2 2.8 12 6.2 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2742) PEHE PF15275.6 CBZ30393.1 - 1.6 9.4 6.8 6 7.5 4.7 2.7 2 0 0 2 2 2 0 PEHE domain TFIIA PF03153.13 CBZ30393.1 - 2.4 8.0 11.3 3.5 7.5 11.3 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Urm1 PF09138.11 CBZ30394.1 - 9.9e-25 86.7 0.0 1.1e-24 86.5 0.0 1.0 1 0 0 1 1 1 1 Urm1 (Ubiquitin related modifier) ThiS PF02597.20 CBZ30394.1 - 1.8e-07 31.7 0.1 2.3e-07 31.4 0.1 1.2 1 0 0 1 1 1 1 ThiS family TGS PF02824.21 CBZ30394.1 - 0.019 15.0 0.2 0.039 14.0 0.2 1.5 1 0 0 1 1 1 0 TGS domain GTP_EFTU PF00009.27 CBZ30395.1 - 5.8e-27 94.5 0.1 9.1e-27 93.9 0.1 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.25 CBZ30395.1 - 8.3e-08 32.5 0.6 2.1e-07 31.3 0.6 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 CBZ30395.1 - 9.6e-07 28.9 0.1 2e-06 27.9 0.1 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 CBZ30395.1 - 0.00034 20.1 0.6 0.0068 15.9 0.2 2.6 2 1 0 2 2 2 1 Signal recognition particle receptor beta subunit cobW PF02492.19 CBZ30395.1 - 0.0072 15.9 2.7 0.011 15.3 0.7 2.2 1 1 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain PduV-EutP PF10662.9 CBZ30395.1 - 0.0099 15.6 0.1 2.8 7.7 0.0 2.3 2 0 0 2 2 2 2 Ethanolamine utilisation - propanediol utilisation YhdX PF17444.2 CBZ30395.1 - 0.047 13.5 0.1 0.096 12.5 0.1 1.4 1 0 0 1 1 1 0 Uncharacterized YhdX-like GTP_EFTU_D4 PF14578.6 CBZ30395.1 - 0.051 13.5 0.0 0.11 12.5 0.0 1.5 1 0 0 1 1 1 0 Elongation factor Tu domain 4 Hexapep PF00132.24 CBZ30396.1 - 1e-09 37.8 11.2 1.8e-06 27.4 1.2 2.7 2 1 0 2 2 2 2 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 CBZ30396.1 - 5.7e-05 22.8 9.8 0.099 12.4 0.5 3.6 2 1 0 3 3 3 3 Hexapeptide repeat of succinyl-transferase Ribosomal_L33 PF00471.20 CBZ30397.1 - 0.052 14.0 0.0 0.089 13.3 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein L33 SAS4 PF15460.6 CBZ30397.1 - 0.078 13.1 0.0 0.1 12.7 0.0 1.2 1 0 0 1 1 1 0 Something about silencing, SAS, complex subunit 4 Ribosomal_L3 PF00297.22 CBZ30398.1 - 5.2e-149 496.2 8.4 6e-149 496.0 8.4 1.0 1 0 0 1 1 1 1 Ribosomal protein L3 Ribosomal_L3 PF00297.22 CBZ30399.1 - 5.2e-149 496.2 8.4 6e-149 496.0 8.4 1.0 1 0 0 1 1 1 1 Ribosomal protein L3 Patatin PF01734.22 CBZ30400.1 - 3.3e-09 37.2 0.9 2.8e-07 30.9 1.0 2.5 2 1 0 2 2 2 1 Patatin-like phospholipase Thioredoxin PF00085.20 CBZ30402.1 - 0.023 14.7 0.0 0.04 13.9 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin EF-hand_7 PF13499.6 CBZ30404.1 - 2.9e-15 56.5 0.0 0.00017 22.0 0.0 4.3 4 1 0 4 4 4 3 EF-hand domain pair EF-hand_6 PF13405.6 CBZ30404.1 - 2.5e-14 51.9 0.0 0.00052 19.7 0.0 6.3 7 0 0 7 7 7 4 EF-hand domain EF-hand_1 PF00036.32 CBZ30404.1 - 5.2e-14 50.7 0.3 0.00022 20.5 0.0 5.6 5 0 0 5 5 5 3 EF hand EF-hand_8 PF13833.6 CBZ30404.1 - 2.2e-13 49.8 0.1 1.4e-08 34.4 0.0 3.9 4 0 0 4 4 4 2 EF-hand domain pair EF-hand_5 PF13202.6 CBZ30404.1 - 2.7e-12 45.6 1.1 0.0068 15.9 0.0 5.6 6 0 0 6 6 6 3 EF hand Spc7 PF08317.11 CBZ30406.1 - 0.00016 20.7 13.9 0.00023 20.2 13.9 1.1 1 0 0 1 1 1 1 Spc7 kinetochore protein ADIP PF11559.8 CBZ30406.1 - 0.36 10.9 17.6 0.5 10.5 17.6 1.2 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding Exonuc_VII_L PF02601.15 CBZ30406.1 - 1.4 8.4 7.2 1.6 8.2 7.2 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit DivIC PF04977.15 CBZ30406.1 - 2.2 8.1 17.9 0.38 10.6 5.9 2.6 1 1 1 2 2 2 0 Septum formation initiator FapA PF03961.13 CBZ30406.1 - 3 6.4 5.2 3.8 6.0 5.2 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A DUF4726 PF15855.5 CBZ30406.1 - 3.3 8.0 7.3 18 5.6 1.2 3.0 2 1 1 3 3 3 0 Domain of unknown function (DUF4726) NDK PF00334.19 CBZ30407.1 - 3.5e-14 53.0 0.0 4e-13 49.5 0.0 2.3 2 1 0 2 2 2 1 Nucleoside diphosphate kinase DUF1126 PF06565.12 CBZ30407.1 - 0.076 12.8 0.0 0.46 10.3 0.0 2.1 1 1 0 1 1 1 0 DUF1126 PH-like domain LRR_6 PF13516.6 CBZ30408.1 - 0.13 12.3 0.2 1.9 8.8 0.0 2.6 2 0 0 2 2 2 0 Leucine Rich repeat Myc_N PF01056.18 CBZ30408.1 - 0.39 10.6 5.4 0.6 10.0 5.4 1.2 1 0 0 1 1 1 0 Myc amino-terminal region Rhodanese PF00581.20 CBZ30410.1 - 6.7e-12 45.9 0.0 1.1e-11 45.2 0.0 1.3 1 0 0 1 1 1 1 Rhodanese-like domain DUF881 PF05949.12 CBZ30410.1 - 0.12 12.3 0.0 0.24 11.3 0.0 1.4 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF881) Pkinase PF00069.25 CBZ30411.1 - 2.6e-20 72.9 0.0 1.5e-19 70.4 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain APH PF01636.23 CBZ30411.1 - 0.0066 16.4 0.2 0.48 10.3 0.0 3.0 2 1 0 3 3 3 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 CBZ30411.1 - 0.011 14.6 0.0 0.019 13.8 0.0 1.4 2 0 0 2 2 2 0 Fungal protein kinase Kdo PF06293.14 CBZ30411.1 - 0.12 11.7 0.0 0.2 11.0 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RMP PF14996.6 CBZ30412.1 - 3.3e-10 40.4 7.2 5.2e-09 36.5 5.0 2.9 2 1 0 2 2 2 1 Retinal Maintenance Adeno_E1B_55K PF01696.17 CBZ30413.1 - 0.00024 19.9 0.8 0.00024 19.9 0.8 2.0 2 0 0 2 2 2 1 Adenovirus EB1 55K protein / large t-antigen Beta_helix PF13229.6 CBZ30413.1 - 0.0017 18.3 0.0 0.4 10.5 0.0 2.4 2 0 0 2 2 2 2 Right handed beta helix region EcKinase PF02958.20 CBZ30413.1 - 0.028 13.7 0.0 0.041 13.2 0.0 1.1 1 0 0 1 1 1 0 Ecdysteroid kinase Pox_Ag35 PF03286.14 CBZ30413.1 - 0.52 10.1 5.7 1.1 9.0 5.7 1.5 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Cyt-b5 PF00173.28 CBZ30414.1 - 9.9e-07 28.8 0.1 2.1e-06 27.8 0.1 1.6 1 1 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Mito_carr PF00153.27 CBZ30415.1 - 1.4e-47 159.6 4.9 2.1e-23 82.1 0.2 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein SWIM PF04434.17 CBZ30416.1 - 0.0053 16.4 10.5 0.066 12.9 2.7 3.4 3 0 0 3 3 3 2 SWIM zinc finger DNA_pol_A_exo1 PF01612.20 CBZ30417.1 - 5e-39 133.8 0.5 8.7e-39 133.0 0.5 1.4 1 0 0 1 1 1 1 3'-5' exonuclease PMC2NT PF08066.12 CBZ30417.1 - 1.4e-18 67.3 0.1 4.9e-18 65.6 0.1 2.0 1 0 0 1 1 1 1 PMC2NT (NUC016) domain HRDC PF00570.23 CBZ30417.1 - 4.5e-08 33.0 0.0 1e-07 31.8 0.0 1.7 1 0 0 1 1 1 1 HRDC domain PIP5K PF01504.18 CBZ30418.1 - 1.4e-71 240.9 0.0 2.2e-71 240.3 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase Sec15 PF04091.12 CBZ30418.1 - 0.037 13.4 0.1 0.068 12.6 0.1 1.3 1 0 0 1 1 1 0 Exocyst complex subunit Sec15-like DUF928 PF06051.12 CBZ30418.1 - 0.098 12.5 0.0 0.17 11.7 0.0 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF928) Bacteriocin_IId PF09221.10 CBZ30419.1 - 0.0041 17.3 0.1 0.011 15.8 0.1 1.9 1 0 0 1 1 1 1 Bacteriocin class IId cyclical uberolysin-like AAA_33 PF13671.6 CBZ30420.1 - 8.1e-14 52.0 0.0 1.2e-13 51.5 0.0 1.2 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 CBZ30420.1 - 0.0014 18.0 0.0 0.0031 16.8 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin KTI12 PF08433.10 CBZ30420.1 - 0.0027 17.2 0.0 0.0032 16.9 0.0 1.1 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_22 PF13401.6 CBZ30420.1 - 0.0039 17.5 0.3 0.024 14.9 0.3 2.0 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.14 CBZ30420.1 - 0.016 15.2 0.0 0.026 14.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) CopD PF05425.13 CBZ30420.1 - 0.038 14.4 0.0 0.067 13.6 0.0 1.4 1 0 0 1 1 1 0 Copper resistance protein D AAA_18 PF13238.6 CBZ30420.1 - 0.13 12.8 0.4 0.22 12.0 0.0 1.6 2 0 0 2 2 2 0 AAA domain TPT PF03151.16 CBZ30421.1 - 1.4e-08 34.4 24.4 1.7e-08 34.1 24.4 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 CBZ30421.1 - 0.0023 18.1 40.2 0.013 15.6 18.4 2.1 2 0 0 2 2 2 2 EamA-like transporter family zf-CCHC PF00098.23 CBZ30423.1 - 0.005 16.9 3.3 0.005 16.9 3.3 3.7 4 0 0 4 4 4 1 Zinc knuckle WW PF00397.26 CBZ30423.1 - 0.0058 16.7 4.0 0.014 15.4 4.0 1.8 1 0 0 1 1 1 1 WW domain zinc-ribbons_6 PF07191.12 CBZ30423.1 - 1.5 8.8 18.6 2.4 8.2 11.6 3.0 2 1 0 2 2 2 0 zinc-ribbons DZR PF12773.7 CBZ30423.1 - 4.6 7.3 18.5 5.4 7.1 0.5 3.1 2 1 0 2 2 2 0 Double zinc ribbon CesT PF05932.13 CBZ30426.1 - 2.5e-13 50.2 0.3 5.7e-13 49.0 0.3 1.6 1 0 0 1 1 1 1 Tir chaperone protein (CesT) family CENP-Q PF13094.6 CBZ30426.1 - 0.0073 16.5 1.4 0.0073 16.5 1.4 2.2 1 1 1 2 2 2 1 CENP-Q, a CENPA-CAD centromere complex subunit bZIP_1 PF00170.21 CBZ30426.1 - 0.019 15.1 0.2 0.019 15.1 0.2 3.3 2 2 1 3 3 3 0 bZIP transcription factor ubiquitin PF00240.23 CBZ30426.1 - 0.039 13.7 0.1 0.1 12.4 0.0 1.7 2 0 0 2 2 2 0 Ubiquitin family Rad60-SLD PF11976.8 CBZ30426.1 - 0.045 13.6 0.0 0.11 12.4 0.0 1.6 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like RRF PF01765.19 CBZ30426.1 - 0.078 12.9 2.3 0.36 10.8 3.0 1.7 2 0 0 2 2 2 0 Ribosome recycling factor PRKG1_interact PF15898.5 CBZ30426.1 - 0.84 10.6 10.9 0.45 11.4 6.4 2.2 1 1 1 2 2 2 0 cGMP-dependent protein kinase interacting domain GBP_C PF02841.14 CBZ30426.1 - 2.3 7.5 9.1 3.5 7.0 9.1 1.2 1 0 0 1 1 1 0 Guanylate-binding protein, C-terminal domain Epimerase PF01370.21 CBZ30428.1 - 3.2e-15 56.2 0.0 9.2e-15 54.8 0.0 1.7 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 CBZ30428.1 - 1e-08 35.3 0.0 2.3e-08 34.2 0.0 1.6 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 CBZ30428.1 - 2.2e-07 30.7 0.0 1.3e-05 24.9 0.0 2.3 2 0 0 2 2 2 1 NmrA-like family 3Beta_HSD PF01073.19 CBZ30428.1 - 3e-07 29.7 0.1 1.7e-06 27.3 0.1 1.9 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 CBZ30428.1 - 3e-05 23.6 0.1 5.6e-05 22.7 0.0 1.5 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase adh_short PF00106.25 CBZ30428.1 - 0.093 12.2 0.1 0.51 9.8 0.0 2.0 2 0 0 2 2 2 0 short chain dehydrogenase Ldh_1_N PF00056.23 CBZ30428.1 - 0.1 12.7 0.1 0.23 11.5 0.1 1.6 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain GCV_H PF01597.19 CBZ30430.1 - 0.00023 21.0 0.0 0.00035 20.5 0.0 1.3 1 0 0 1 1 1 1 Glycine cleavage H-protein AAA_lid_2 PF17863.1 CBZ30430.1 - 0.023 14.5 0.9 1.9 8.4 0.6 2.2 2 0 0 2 2 2 0 AAA lid domain DUF4189 PF13827.6 CBZ30430.1 - 0.19 12.3 2.2 1.2 9.8 2.2 2.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4189) PhoLip_ATPase_C PF16212.5 CBZ30431.1 - 5.8e-36 124.5 25.3 5.8e-36 124.5 25.3 2.5 3 0 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 CBZ30431.1 - 1.1e-13 50.7 4.4 2.9e-13 49.3 4.4 1.8 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal E1-E2_ATPase PF00122.20 CBZ30431.1 - 1.4e-13 50.8 1.6 3.4e-13 49.5 0.1 2.4 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.26 CBZ30431.1 - 5.4e-10 39.9 0.4 0.0032 17.8 0.1 3.4 3 0 0 3 3 3 3 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 CBZ30431.1 - 2e-08 34.2 0.0 1e-07 31.9 0.0 2.1 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 CBZ30431.1 - 0.0018 18.1 0.2 0.0029 17.4 0.2 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Ribosomal_L2 PF00181.23 CBZ30431.1 - 0.083 12.9 0.0 0.21 11.6 0.0 1.6 1 0 0 1 1 1 0 Ribosomal Proteins L2, RNA binding domain HA2 PF04408.23 CBZ30432.1 - 3.2e-15 56.3 0.3 1.6e-14 54.1 0.0 2.5 2 0 0 2 2 2 1 Helicase associated domain (HA2) Helicase_C PF00271.31 CBZ30432.1 - 4.3e-12 46.4 0.1 1.6e-11 44.5 0.1 2.0 1 1 0 1 1 1 1 Helicase conserved C-terminal domain dsrm PF00035.26 CBZ30432.1 - 2.6e-11 44.1 0.0 0.0012 19.5 0.0 4.7 4 0 0 4 4 4 3 Double-stranded RNA binding motif DEAD PF00270.29 CBZ30432.1 - 6.9e-08 32.4 0.1 1.6e-07 31.3 0.1 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 CBZ30432.1 - 8.8e-05 22.8 0.2 0.00037 20.8 0.1 2.1 2 0 0 2 2 2 1 AAA domain AAA_23 PF13476.6 CBZ30432.1 - 0.046 14.2 0.0 0.11 13.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.6 CBZ30432.1 - 0.09 12.8 0.4 4.1 7.4 0.4 2.6 1 1 0 1 1 1 0 AAA domain ATPase PF06745.13 CBZ30432.1 - 0.16 11.2 0.0 0.32 10.3 0.0 1.4 1 0 0 1 1 1 0 KaiC TPP_enzyme_N PF02776.18 CBZ30434.1 - 8.3e-33 113.4 0.0 1.9e-32 112.3 0.0 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.21 CBZ30434.1 - 5.6e-20 71.7 0.1 2.2e-19 69.7 0.0 2.1 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.22 CBZ30434.1 - 1.9e-17 63.3 0.1 4.6e-17 62.0 0.1 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain DRMBL PF07522.14 CBZ30435.1 - 3e-19 69.2 0.0 5.3e-19 68.4 0.0 1.4 1 0 0 1 1 1 1 DNA repair metallo-beta-lactamase DUF4379 PF14311.6 CBZ30436.1 - 6.4e-16 58.5 0.3 1.2e-15 57.6 0.3 1.5 1 0 0 1 1 1 1 Probable Zinc-ribbon domain zf-UBP PF02148.19 CBZ30437.1 - 9e-16 58.0 8.4 9e-16 58.0 8.4 2.4 2 0 0 2 2 2 1 Zn-finger in ubiquitin-hydrolases and other protein LuxC PF05893.14 CBZ30437.1 - 0.029 13.4 0.3 0.051 12.6 0.3 1.3 1 0 0 1 1 1 0 Acyl-CoA reductase (LuxC) UPF0054 PF02130.17 CBZ30439.1 - 7.6e-22 77.5 0.0 1e-21 77.0 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized protein family UPF0054 LRR_6 PF13516.6 CBZ30440.1 - 4.1e-05 23.3 8.2 0.03 14.4 1.4 4.6 4 0 0 4 4 4 2 Leucine Rich repeat LRR_1 PF00560.33 CBZ30440.1 - 0.13 12.9 2.6 14 6.7 0.1 4.2 4 0 0 4 4 4 0 Leucine Rich Repeat LRR_8 PF13855.6 CBZ30440.1 - 0.16 11.8 1.4 3 7.7 0.9 2.9 1 1 1 2 2 2 0 Leucine rich repeat LRR_4 PF12799.7 CBZ30440.1 - 0.23 11.9 3.5 4.6 7.8 0.5 3.1 1 1 3 4 4 4 0 Leucine Rich repeats (2 copies) p450 PF00067.22 CBZ30442.1 - 4.5e-61 207.0 0.0 6.4e-61 206.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 DUF1477 PF07346.11 CBZ30442.1 - 0.0038 17.5 0.3 0.0081 16.4 0.3 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1477) AAA PF00004.29 CBZ30444.1 - 6.2e-35 120.5 0.0 1.2e-34 119.6 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 CBZ30444.1 - 4.2e-05 24.0 0.3 0.00027 21.3 0.3 2.5 1 1 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.14 CBZ30444.1 - 4.2e-05 23.6 0.0 0.00022 21.2 0.0 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 CBZ30444.1 - 0.00032 21.0 0.1 0.082 13.2 0.1 2.7 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.12 CBZ30444.1 - 0.00049 19.9 0.0 0.0024 17.6 0.0 2.1 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain NACHT PF05729.12 CBZ30444.1 - 0.0028 17.6 0.2 2.2 8.2 0.0 2.8 2 1 1 3 3 3 2 NACHT domain TIP49 PF06068.13 CBZ30444.1 - 0.0052 16.0 0.0 0.012 14.9 0.0 1.6 2 0 0 2 2 2 1 TIP49 P-loop domain AAA_17 PF13207.6 CBZ30444.1 - 0.01 16.2 0.0 0.023 15.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 CBZ30444.1 - 0.011 15.5 0.0 0.019 14.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 CBZ30444.1 - 0.011 15.9 0.0 0.038 14.1 0.0 1.9 1 1 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 CBZ30444.1 - 0.011 15.4 0.5 0.024 14.4 0.0 1.8 2 0 0 2 2 2 0 IstB-like ATP binding protein Vps4_C PF09336.10 CBZ30444.1 - 0.021 14.8 0.0 0.061 13.3 0.0 1.8 1 0 0 1 1 1 0 Vps4 C terminal oligomerisation domain Hydin_ADK PF17213.3 CBZ30444.1 - 0.03 14.6 0.1 0.18 12.0 0.0 2.1 2 0 0 2 2 2 0 Hydin Adenylate kinase-like domain AAA_14 PF13173.6 CBZ30444.1 - 0.038 14.0 0.0 0.087 12.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 CBZ30444.1 - 0.074 12.4 0.1 0.34 10.2 0.1 2.0 1 1 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_2 PF07724.14 CBZ30444.1 - 0.097 12.8 0.0 0.24 11.5 0.0 1.6 2 0 0 2 2 2 0 AAA domain (Cdc48 subfamily) AAA_19 PF13245.6 CBZ30444.1 - 0.16 12.3 0.0 0.92 9.8 0.0 2.1 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 CBZ30444.1 - 0.16 12.4 0.0 0.98 9.8 0.0 2.1 2 0 0 2 2 2 0 RNA helicase Tyr_Deacylase PF02580.16 CBZ30445.1 - 1.2e-27 97.2 0.0 1.7e-27 96.7 0.0 1.2 1 0 0 1 1 1 1 D-Tyr-tRNA(Tyr) deacylase POLO_box PF00659.18 CBZ30446.1 - 0.15 12.3 0.2 0.58 10.4 0.2 2.0 1 1 0 1 1 1 0 POLO box duplicated region Aldose_epim PF01263.20 CBZ30447.1 - 4.8e-33 114.7 0.0 5.9e-33 114.5 0.0 1.1 1 0 0 1 1 1 1 Aldose 1-epimerase HECT PF00632.25 CBZ30448.1 - 3.1e-10 40.0 0.0 0.0052 16.3 0.0 3.1 3 0 0 3 3 3 3 HECT-domain (ubiquitin-transferase) HECT PF00632.25 CBZ30449.1 - 3.1e-08 33.4 0.0 4.1e-07 29.8 0.2 2.0 2 0 0 2 2 2 1 HECT-domain (ubiquitin-transferase) Lactamase_B PF00753.27 CBZ30451.1 - 1.7e-07 31.4 0.1 7.6e-07 29.3 0.1 1.9 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 CBZ30451.1 - 0.012 15.1 0.0 0.026 14.1 0.0 1.7 1 0 0 1 1 1 0 Beta-lactamase superfamily domain HAGH_C PF16123.5 CBZ30451.1 - 0.033 14.7 0.0 0.076 13.5 0.0 1.6 1 0 0 1 1 1 0 Hydroxyacylglutathione hydrolase C-terminus DBP10CT PF08147.12 CBZ30451.1 - 0.18 12.1 0.0 0.35 11.1 0.0 1.4 1 0 0 1 1 1 0 DBP10CT (NUC160) domain Beta-Casp PF10996.8 CBZ30452.1 - 6.5e-32 110.1 0.0 2.8e-31 108.0 0.0 2.2 2 0 0 2 2 2 1 Beta-Casp domain CPSF73-100_C PF11718.8 CBZ30452.1 - 1.7e-28 99.7 0.0 2.5e-28 99.1 0.0 1.3 1 0 0 1 1 1 1 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term Lactamase_B PF00753.27 CBZ30452.1 - 8.7e-24 84.6 0.0 1.5e-23 83.8 0.0 1.4 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_6 PF16661.5 CBZ30452.1 - 1.5e-16 60.4 0.0 3.8e-16 59.1 0.0 1.6 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily domain RMMBL PF07521.12 CBZ30452.1 - 6.2e-13 48.5 0.0 2.4e-12 46.6 0.0 2.0 2 0 0 2 2 2 1 Zn-dependent metallo-hydrolase RNA specificity domain Lactamase_B_2 PF12706.7 CBZ30452.1 - 2.1e-10 40.4 0.1 4.2e-08 32.9 0.0 2.4 2 0 0 2 2 2 2 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 CBZ30452.1 - 0.00065 19.6 0.0 0.0028 17.5 0.0 2.1 2 1 0 2 2 2 1 Beta-lactamase superfamily domain Topoisom_I_N PF02919.15 CBZ30453.1 - 1.5e-91 305.6 1.3 1.5e-91 305.6 1.3 3.2 2 1 0 2 2 2 1 Eukaryotic DNA topoisomerase I, DNA binding fragment Topoisom_I PF01028.20 CBZ30453.1 - 1.8e-91 305.5 1.0 1.8e-91 305.5 1.0 1.8 2 0 0 2 2 2 1 Eukaryotic DNA topoisomerase I, catalytic core DUF3891 PF13030.6 CBZ30453.1 - 0.021 14.6 2.6 0.62 9.8 1.5 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3891) CENP-B_dimeris PF09026.10 CBZ30453.1 - 5.9 7.3 8.2 2.2 8.8 0.4 2.9 2 0 0 2 2 2 0 Centromere protein B dimerisation domain LRR_9 PF14580.6 CBZ30454.1 - 1.1e-06 28.2 0.1 2.4e-06 27.2 0.1 1.5 1 0 0 1 1 1 1 Leucine-rich repeat Ribosomal_L3 PF00297.22 CBZ30454.1 - 0.016 14.2 0.1 0.026 13.5 0.1 1.2 1 0 0 1 1 1 0 Ribosomal protein L3 LRR_4 PF12799.7 CBZ30454.1 - 0.021 15.3 0.0 0.021 15.3 0.0 2.5 3 0 0 3 3 3 0 Leucine Rich repeats (2 copies) bZIP_1 PF00170.21 CBZ30454.1 - 0.1 12.7 4.1 0.16 12.1 0.4 2.8 3 0 0 3 3 3 0 bZIP transcription factor zf-RanBP PF00641.18 CBZ30455.1 - 2.5e-05 23.5 2.6 2.5e-05 23.5 2.6 1.7 2 0 0 2 2 2 1 Zn-finger in Ran binding protein and others zf-CCCH_4 PF18044.1 CBZ30455.1 - 0.00072 19.3 8.8 0.0008 19.1 1.0 3.2 3 0 0 3 3 3 1 CCCH-type zinc finger zf_CCCH_4 PF18345.1 CBZ30455.1 - 0.0073 16.3 1.5 0.022 14.8 1.5 1.9 1 0 0 1 1 1 1 Zinc finger domain zf-CCCH PF00642.24 CBZ30455.1 - 0.14 12.1 1.8 0.42 10.6 1.8 1.8 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Amidinotransf PF02274.17 CBZ30456.1 - 1.2e-10 41.0 0.0 1.3e-10 40.9 0.0 1.1 1 0 0 1 1 1 1 Amidinotransferase LRR_6 PF13516.6 CBZ30457.1 - 0.41 10.8 1.7 0.77 10.0 0.0 2.3 2 0 0 2 2 2 0 Leucine Rich repeat TPR_12 PF13424.6 CBZ30458.1 - 3.9e-33 113.6 21.8 4.8e-08 33.2 3.5 6.8 2 1 5 7 7 7 7 Tetratricopeptide repeat TPR_10 PF13374.6 CBZ30458.1 - 4.9e-26 89.8 28.2 1.9e-08 33.9 0.0 7.4 8 0 0 8 8 8 6 Tetratricopeptide repeat TPR_8 PF13181.6 CBZ30458.1 - 7.7e-07 28.8 26.7 0.027 14.7 0.2 8.1 8 0 0 8 8 8 2 Tetratricopeptide repeat Drf_FH3 PF06367.16 CBZ30458.1 - 0.0025 17.5 0.0 0.0045 16.6 0.0 1.3 1 0 0 1 1 1 1 Diaphanous FH3 Domain DUF3301 PF11743.8 CBZ30458.1 - 0.026 14.2 2.5 2.1 8.1 0.0 3.1 2 2 1 3 3 3 0 Protein of unknown function (DUF3301) TPR_17 PF13431.6 CBZ30458.1 - 0.061 13.7 8.5 14 6.4 0.0 5.9 6 0 0 6 6 6 0 Tetratricopeptide repeat DUF2225 PF09986.9 CBZ30458.1 - 0.081 12.6 2.2 6.6 6.4 0.1 3.1 1 1 2 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2225) TPR_7 PF13176.6 CBZ30458.1 - 0.19 11.8 19.1 0.38 10.9 0.0 6.9 8 0 0 8 8 8 0 Tetratricopeptide repeat YfdX PF10938.8 CBZ30458.1 - 0.25 11.3 4.5 0.19 11.6 0.6 2.5 2 0 0 2 2 2 0 YfdX protein TPR_1 PF00515.28 CBZ30458.1 - 2.4 8.1 18.5 15 5.6 0.1 6.6 7 0 0 7 7 7 0 Tetratricopeptide repeat TIP49 PF06068.13 CBZ30459.1 - 1.1e-166 554.3 1.1 1.4e-166 554.0 1.1 1.1 1 0 0 1 1 1 1 TIP49 P-loop domain TIP49_C PF17856.1 CBZ30459.1 - 9.4e-21 73.7 0.6 3.3e-20 72.0 0.1 2.3 2 0 0 2 2 1 1 TIP49 AAA-lid domain RuvB_N PF05496.12 CBZ30459.1 - 8.1e-12 45.2 0.0 4e-08 33.2 0.0 2.5 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA PF00004.29 CBZ30459.1 - 9.5e-12 45.5 1.0 3.2e-07 30.8 0.1 3.0 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 CBZ30459.1 - 7.7e-07 29.5 0.1 0.01 16.1 0.0 2.5 2 1 0 2 2 2 2 AAA domain AAA_16 PF13191.6 CBZ30459.1 - 3.4e-05 24.3 0.1 0.00044 20.7 0.1 2.3 1 1 0 1 1 1 1 AAA ATPase domain Mg_chelatase PF01078.21 CBZ30459.1 - 0.00023 20.6 0.3 0.013 14.9 0.1 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 CBZ30459.1 - 0.00023 21.2 0.2 0.09 12.8 0.0 2.5 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_19 PF13245.6 CBZ30459.1 - 0.0015 18.9 0.1 1.5 9.1 0.0 2.5 2 0 0 2 2 2 2 AAA domain DnaB_C PF03796.15 CBZ30459.1 - 0.0042 16.5 0.0 0.014 14.7 0.0 1.8 2 0 0 2 2 2 1 DnaB-like helicase C terminal domain AAA_25 PF13481.6 CBZ30459.1 - 0.0049 16.5 0.0 0.0088 15.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 CBZ30459.1 - 0.0059 16.8 0.0 0.024 14.8 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.6 CBZ30459.1 - 0.013 15.3 0.0 0.052 13.3 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 CBZ30459.1 - 0.014 15.9 0.1 0.05 14.1 0.0 2.0 2 0 0 2 2 2 0 AAA domain ResIII PF04851.15 CBZ30459.1 - 0.014 15.4 0.1 0.96 9.4 0.0 2.3 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit AAA_28 PF13521.6 CBZ30459.1 - 0.016 15.5 0.0 0.035 14.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 CBZ30459.1 - 0.034 14.1 0.0 0.073 13.1 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_7 PF12775.7 CBZ30459.1 - 0.043 13.3 0.3 0.25 10.8 0.0 2.2 2 1 0 2 2 2 0 P-loop containing dynein motor region IstB_IS21 PF01695.17 CBZ30459.1 - 0.046 13.4 0.1 0.15 11.8 0.1 1.8 1 0 0 1 1 1 0 IstB-like ATP binding protein Sigma54_activat PF00158.26 CBZ30459.1 - 0.052 13.2 0.1 10 5.8 0.0 2.5 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_17 PF13207.6 CBZ30459.1 - 0.088 13.2 1.0 0.88 10.0 0.1 2.9 2 1 1 3 3 3 0 AAA domain NACHT PF05729.12 CBZ30459.1 - 0.11 12.5 0.0 0.23 11.3 0.0 1.6 1 0 0 1 1 1 0 NACHT domain RNA_helicase PF00910.22 CBZ30459.1 - 0.15 12.5 0.1 0.52 10.7 0.0 2.0 2 0 0 2 2 1 0 RNA helicase SET PF00856.28 CBZ30460.1 - 0.00098 19.5 0.0 0.0017 18.7 0.0 1.4 1 1 0 1 1 1 1 SET domain AAA PF00004.29 CBZ30461.1 - 1.3e-48 164.8 0.0 1.1e-37 129.4 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) PEX-1N PF09262.11 CBZ30461.1 - 1.8e-15 57.1 0.2 4.7e-15 55.8 0.2 1.8 1 0 0 1 1 1 1 Peroxisome biogenesis factor 1, N-terminal AAA_16 PF13191.6 CBZ30461.1 - 1.3e-12 48.4 1.9 5.3e-05 23.7 0.1 4.0 2 2 2 4 4 4 2 AAA ATPase domain AAA_22 PF13401.6 CBZ30461.1 - 2e-08 34.6 0.1 0.0044 17.3 0.0 3.2 2 1 1 3 3 3 2 AAA domain AAA_7 PF12775.7 CBZ30461.1 - 1.6e-07 31.0 0.0 0.012 15.1 0.0 2.4 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA_33 PF13671.6 CBZ30461.1 - 1e-06 29.0 0.0 0.014 15.5 0.0 2.8 2 0 0 2 2 2 2 AAA domain DUF815 PF05673.13 CBZ30461.1 - 1.3e-06 27.8 0.0 0.0012 18.1 0.0 2.7 3 0 0 3 3 3 2 Protein of unknown function (DUF815) AAA_5 PF07728.14 CBZ30461.1 - 3.6e-05 23.8 0.1 0.083 12.9 0.0 3.2 3 1 0 3 3 2 2 AAA domain (dynein-related subfamily) AAA_14 PF13173.6 CBZ30461.1 - 4.8e-05 23.4 0.0 0.0078 16.2 0.0 2.3 2 0 0 2 2 2 1 AAA domain ATP-synt_ab PF00006.25 CBZ30461.1 - 5.3e-05 23.0 0.0 0.073 12.7 0.0 2.4 2 0 0 2 2 2 2 ATP synthase alpha/beta family, nucleotide-binding domain AAA_29 PF13555.6 CBZ30461.1 - 9.3e-05 22.1 0.0 0.27 11.0 0.0 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_25 PF13481.6 CBZ30461.1 - 0.00012 21.7 0.8 3.3 7.2 0.0 4.8 3 1 1 4 4 4 1 AAA domain ABC_tran PF00005.27 CBZ30461.1 - 0.00012 22.6 0.0 0.43 11.1 0.0 2.9 3 0 0 3 3 2 2 ABC transporter RNA_helicase PF00910.22 CBZ30461.1 - 0.00017 21.9 0.0 0.068 13.6 0.0 3.0 3 0 0 3 3 2 1 RNA helicase AAA_2 PF07724.14 CBZ30461.1 - 0.00063 19.9 0.0 0.0019 18.4 0.0 1.8 2 0 0 2 2 1 1 AAA domain (Cdc48 subfamily) IstB_IS21 PF01695.17 CBZ30461.1 - 0.00064 19.5 0.0 1.2 8.9 0.0 2.4 2 0 0 2 2 2 2 IstB-like ATP binding protein T2SSE PF00437.20 CBZ30461.1 - 0.00068 18.8 0.0 0.41 9.6 0.0 2.3 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_19 PF13245.6 CBZ30461.1 - 0.00071 19.9 0.0 0.32 11.3 0.0 2.7 2 0 0 2 2 2 1 AAA domain Rad17 PF03215.15 CBZ30461.1 - 0.0013 18.7 0.0 0.58 10.0 0.0 2.3 2 0 0 2 2 2 1 Rad17 P-loop domain Vps4_C PF09336.10 CBZ30461.1 - 0.0017 18.3 0.0 0.0058 16.6 0.0 1.8 1 0 0 1 1 1 1 Vps4 C terminal oligomerisation domain RsgA_GTPase PF03193.16 CBZ30461.1 - 0.0018 18.2 0.0 2.1 8.2 0.0 2.6 2 0 0 2 2 2 1 RsgA GTPase Mg_chelatase PF01078.21 CBZ30461.1 - 0.0025 17.2 0.0 1.2 8.5 0.0 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.26 CBZ30461.1 - 0.0026 17.5 0.0 3.1 7.5 0.0 2.9 3 0 0 3 3 2 1 Sigma-54 interaction domain TsaE PF02367.17 CBZ30461.1 - 0.0027 17.7 0.0 1.8 8.5 0.0 2.4 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_lid_3 PF17862.1 CBZ30461.1 - 0.0032 17.2 0.0 0.18 11.7 0.0 2.7 2 0 0 2 2 2 1 AAA+ lid domain AAA_28 PF13521.6 CBZ30461.1 - 0.0041 17.4 0.0 1.9 8.7 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_23 PF13476.6 CBZ30461.1 - 0.0042 17.6 0.0 4.8 7.6 0.0 2.2 2 0 0 2 2 2 0 AAA domain ATPase_2 PF01637.18 CBZ30461.1 - 0.0047 16.9 0.1 0.064 13.2 0.0 2.4 2 1 1 3 3 3 1 ATPase domain predominantly from Archaea NACHT PF05729.12 CBZ30461.1 - 0.013 15.4 1.1 3.8 7.4 0.0 3.6 3 1 1 4 4 3 0 NACHT domain AAA_24 PF13479.6 CBZ30461.1 - 0.02 14.6 0.1 2 8.1 0.0 2.4 2 0 0 2 2 2 0 AAA domain TniB PF05621.11 CBZ30461.1 - 0.025 14.0 0.0 1.4 8.3 0.0 2.7 2 0 0 2 2 2 0 Bacterial TniB protein RuvB_N PF05496.12 CBZ30461.1 - 0.061 13.1 0.0 4.9 6.9 0.0 2.7 3 0 0 3 3 3 0 Holliday junction DNA helicase RuvB P-loop domain FtsK_SpoIIIE PF01580.18 CBZ30461.1 - 0.062 12.6 0.2 0.16 11.3 0.0 1.7 2 0 0 2 2 1 0 FtsK/SpoIIIE family MCM PF00493.23 CBZ30461.1 - 0.084 12.0 0.0 1.8 7.6 0.0 2.4 2 0 0 2 2 2 0 MCM P-loop domain AAA_18 PF13238.6 CBZ30461.1 - 0.094 13.3 0.0 6.2 7.4 0.0 2.9 3 0 0 3 3 2 0 AAA domain NB-ARC PF00931.22 CBZ30461.1 - 0.12 11.5 0.0 1.7 7.8 0.0 2.2 2 0 0 2 2 2 0 NB-ARC domain NTPase_1 PF03266.15 CBZ30461.1 - 0.14 12.1 0.4 4.3 7.2 0.2 2.5 2 0 0 2 2 2 0 NTPase Bac_DnaA PF00308.18 CBZ30461.1 - 0.16 11.8 0.0 7 6.4 0.0 2.6 3 0 0 3 3 2 0 Bacterial dnaA protein Zeta_toxin PF06414.12 CBZ30461.1 - 0.17 11.1 0.0 17 4.7 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin LicD PF04991.13 CBZ30463.1 - 4.7e-07 30.2 0.2 0.0059 16.8 0.4 2.1 1 1 0 2 2 2 2 LicD family Deltaretro_Tax PF05599.11 CBZ30463.1 - 0.071 13.6 0.0 0.17 12.4 0.0 1.6 1 0 0 1 1 1 0 Deltaretrovirus Tax protein NTP_transf_2 PF01909.23 CBZ30463.1 - 0.11 12.8 0.0 0.16 12.3 0.0 1.3 1 0 0 1 1 1 0 Nucleotidyltransferase domain PDCD2_C PF04194.13 CBZ30464.1 - 1.3e-23 84.0 0.1 1.3e-23 84.0 0.1 2.3 3 0 0 3 3 3 1 Programmed cell death protein 2, C-terminal putative domain Elf1 PF05129.13 CBZ30464.1 - 0.038 14.0 0.6 0.13 12.3 0.1 2.1 2 0 0 2 2 2 0 Transcription elongation factor Elf1 like zf-RRN7 PF11781.8 CBZ30464.1 - 0.16 11.7 1.7 1.9 8.2 0.1 2.6 2 0 0 2 2 2 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 Zn-ribbon_8 PF09723.10 CBZ30464.1 - 0.61 10.2 4.0 13 6.0 0.2 3.2 3 0 0 3 3 3 0 Zinc ribbon domain CpXC PF14353.6 CBZ30464.1 - 5.3 7.1 5.6 33 4.6 0.0 2.8 2 1 0 2 2 2 0 CpXC protein Ank_2 PF12796.7 CBZ30465.1 - 9.6e-29 99.8 2.7 9.2e-13 48.6 0.1 3.1 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CBZ30465.1 - 3.1e-21 75.4 0.6 3.4e-05 24.3 0.2 5.2 1 1 4 5 5 5 5 Ankyrin repeats (many copies) Ank PF00023.30 CBZ30465.1 - 1e-20 73.2 2.9 6.6e-05 23.2 0.1 5.3 5 0 0 5 5 5 5 Ankyrin repeat Ank_3 PF13606.6 CBZ30465.1 - 7.5e-20 68.9 0.3 8.9e-05 22.6 0.1 5.4 5 0 0 5 5 5 4 Ankyrin repeat Ank_5 PF13857.6 CBZ30465.1 - 1.9e-17 63.1 7.2 3.8e-06 27.1 0.3 4.4 2 1 2 4 4 4 4 Ankyrin repeats (many copies) DUF3372 PF11852.8 CBZ30465.1 - 0.064 12.7 0.0 0.12 11.9 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3372) PI3_PI4_kinase PF00454.27 CBZ30468.1 - 2.1e-34 119.5 0.0 2e-31 109.7 0.0 2.4 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase DUF4135 PF13575.6 CBZ30468.1 - 0.011 15.2 0.1 0.033 13.5 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4135) PfkB PF00294.24 CBZ30469.1 - 1.1e-43 149.7 0.1 7.3e-43 147.0 0.1 1.9 1 1 0 1 1 1 1 pfkB family carbohydrate kinase Complex1_LYR PF05347.15 CBZ30470.1 - 1.1e-08 35.0 0.5 1.9e-08 34.3 0.5 1.4 1 0 0 1 1 1 1 Complex 1 protein (LYR family) DUF3336 PF11815.8 CBZ30471.1 - 6.7e-20 71.2 0.0 1.9e-19 69.8 0.0 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF3336) Patatin PF01734.22 CBZ30471.1 - 2e-09 38.0 0.2 3.6e-09 37.1 0.2 1.4 1 0 0 1 1 1 1 Patatin-like phospholipase Metallophos PF00149.28 CBZ30472.1 - 3.9e-06 27.5 0.0 9.7e-06 26.2 0.0 1.7 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 CBZ30472.1 - 0.002 18.3 0.0 0.1 12.7 0.0 2.3 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Alkyl_sulf_dimr PF14863.6 CBZ30473.1 - 0.11 12.9 0.3 0.16 12.4 0.3 1.2 1 0 0 1 1 1 0 Alkyl sulfatase dimerisation Arif-1 PF06770.11 CBZ30474.1 - 0.013 15.2 0.0 0.016 14.9 0.0 1.1 1 0 0 1 1 1 0 Actin-rearrangement-inducing factor (Arif-1) Alkyl_sulf_dimr PF14863.6 CBZ30475.1 - 0.11 12.9 0.3 0.16 12.4 0.3 1.2 1 0 0 1 1 1 0 Alkyl sulfatase dimerisation Ribosomal_L21e PF01157.18 CBZ30476.1 - 1.3e-40 137.3 3.1 2.1e-40 136.7 3.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L21e EMP70 PF02990.16 CBZ30477.1 - 1.8e-134 449.3 1.1 2.3e-134 448.9 1.1 1.1 1 0 0 1 1 1 1 Endomembrane protein 70 Neurensin PF14927.6 CBZ30477.1 - 0.16 11.7 1.2 4.3 7.0 0.0 3.0 2 1 0 2 2 2 0 Neurensin ATP-synt_ab PF00006.25 CBZ30478.1 - 2.1e-105 351.1 0.0 3.5e-105 350.4 0.0 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_Xtn PF16886.5 CBZ30478.1 - 1.5e-43 147.5 0.5 3.1e-43 146.5 0.1 1.8 2 0 0 2 2 2 1 ATPsynthase alpha/beta subunit N-term extension ATP-synt_ab_N PF02874.23 CBZ30478.1 - 1.7e-15 57.3 1.5 1.7e-15 57.3 1.5 2.4 3 0 0 3 3 3 1 ATP synthase alpha/beta family, beta-barrel domain DUF2118 PF09891.9 CBZ30478.1 - 0.098 12.6 0.0 0.24 11.4 0.0 1.6 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2118) DUF2737 PF10930.8 CBZ30478.1 - 0.099 12.2 0.1 5.9 6.5 0.1 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF2737) Ribosomal_L13 PF00572.18 CBZ30479.1 - 1.9e-28 99.2 0.1 2.5e-28 98.8 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L13 Ins_P5_2-kin PF06090.12 CBZ30481.1 - 4.8e-26 92.0 0.0 6.5e-26 91.5 0.0 1.3 1 1 0 1 1 1 1 Inositol-pentakisphosphate 2-kinase DUF501 PF04417.12 CBZ30483.1 - 5.9e-29 100.7 0.5 9.8e-29 99.9 0.5 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF501) HTH_Tnp_Mu_2 PF09039.11 CBZ30483.1 - 0.12 12.4 0.0 0.27 11.3 0.0 1.6 1 0 0 1 1 1 0 Mu DNA binding, I gamma subdomain DUF4148 PF13663.6 CBZ30484.1 - 2.2 8.5 6.7 14 5.9 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4148) Aminotran_1_2 PF00155.21 CBZ30485.1 - 2.4e-45 155.3 0.0 3e-45 155.0 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II LIM PF00412.22 CBZ30487.1 - 0.2 11.9 7.6 0.47 10.7 7.6 1.7 1 0 0 1 1 1 0 LIM domain Lar_restr_allev PF14354.6 CBZ30487.1 - 0.57 10.6 7.0 17 5.9 0.0 2.8 2 0 0 2 2 2 0 Restriction alleviation protein Lar Actin PF00022.19 CBZ30488.1 - 1.8e-37 128.9 0.0 2.4e-36 125.2 0.0 2.4 1 1 0 1 1 1 1 Actin FtsA PF14450.6 CBZ30488.1 - 0.0015 18.9 0.0 0.0025 18.2 0.0 1.5 1 1 0 1 1 1 1 Cell division protein FtsA PGM_PMM_I PF02878.16 CBZ30490.1 - 4.5e-37 126.9 0.0 1e-36 125.7 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_II PF02879.16 CBZ30490.1 - 1.6e-20 73.7 0.0 5.4e-20 71.9 0.0 2.0 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_III PF02880.16 CBZ30490.1 - 7.6e-15 55.1 0.0 2.1e-14 53.7 0.1 1.8 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_IV PF00408.20 CBZ30490.1 - 4.2e-06 26.9 0.0 1.3e-05 25.2 0.0 1.9 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain ANAPC4_WD40 PF12894.7 CBZ30491.1 - 0.027 14.8 0.0 40 4.6 0.0 4.5 4 2 1 5 5 5 0 Anaphase-promoting complex subunit 4 WD40 domain Ribosomal_L14 PF00238.19 CBZ30494.1 - 6e-22 78.0 0.1 9.9e-22 77.3 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e TPR_1 PF00515.28 CBZ30495.1 - 1.1e-09 37.6 3.3 0.058 13.2 0.0 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 CBZ30495.1 - 1.2e-08 34.4 4.7 0.17 12.1 0.0 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_12 PF13424.6 CBZ30495.1 - 0.0004 20.6 1.3 1.6 9.1 0.1 3.7 2 1 2 4 4 4 3 Tetratricopeptide repeat TPR_11 PF13414.6 CBZ30495.1 - 0.00064 19.4 0.1 0.018 14.7 0.0 2.9 3 0 0 3 3 3 1 TPR repeat TPR_16 PF13432.6 CBZ30495.1 - 0.0023 18.5 0.1 2 9.2 0.1 3.0 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.6 CBZ30495.1 - 0.016 15.3 3.4 2 8.8 0.0 3.5 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_19 PF14559.6 CBZ30495.1 - 0.02 15.4 0.7 1.8 9.2 0.1 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat ANAPC3 PF12895.7 CBZ30495.1 - 0.027 14.7 4.6 0.43 10.8 1.4 3.2 2 1 1 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 Atg14 PF10186.9 CBZ30496.1 - 0.0043 16.2 5.9 0.0043 16.2 5.9 1.9 2 0 0 2 2 2 1 Vacuolar sorting 38 and autophagy-related subunit 14 Borrelia_P83 PF05262.11 CBZ30496.1 - 0.021 13.4 2.1 0.023 13.2 2.1 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein V_ATPase_I PF01496.19 CBZ30496.1 - 0.045 11.7 1.0 0.044 11.7 1.0 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Nup88 PF10168.9 CBZ30496.1 - 0.063 11.1 4.4 0.076 10.8 4.4 1.1 1 0 0 1 1 1 0 Nuclear pore component LMBR1 PF04791.16 CBZ30496.1 - 0.099 11.5 1.5 0.12 11.3 1.5 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein PUFD PF16553.5 CBZ30496.1 - 0.19 11.9 1.0 0.46 10.6 1.0 1.6 1 0 0 1 1 1 0 BCORL-PCGF1-binding domain DUF572 PF04502.13 CBZ30496.1 - 0.29 10.7 4.4 0.43 10.2 4.4 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF572) MPS2 PF17060.5 CBZ30496.1 - 0.36 10.0 3.2 0.54 9.5 3.2 1.2 1 0 0 1 1 1 0 Monopolar spindle protein 2 DUF3644 PF12358.8 CBZ30496.1 - 0.42 11.1 1.8 5 7.7 0.8 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3644) MIP PF00230.20 CBZ30498.1 - 2.5e-34 118.9 19.7 1.8e-33 116.2 19.7 1.9 1 1 0 1 1 1 1 Major intrinsic protein LSM PF01423.22 CBZ30499.1 - 2.1e-12 46.6 0.2 2.6e-12 46.3 0.2 1.2 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 CBZ30499.1 - 0.0027 17.8 0.1 0.0042 17.2 0.1 1.3 1 0 0 1 1 1 1 Ataxin 2 SM domain DnaJ PF00226.31 CBZ30500.1 - 1.9e-18 66.4 0.0 3.4e-18 65.5 0.0 1.5 1 0 0 1 1 1 1 DnaJ domain APH_6_hur PF04655.14 CBZ30500.1 - 0.051 12.9 0.1 0.11 11.8 0.1 1.5 1 0 0 1 1 1 0 Aminoglycoside/hydroxyurea antibiotic resistance kinase TPR_14 PF13428.6 CBZ30500.1 - 1 10.4 4.9 98 4.2 0.0 4.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_19 PF14559.6 CBZ30500.1 - 4.7 7.8 6.6 9.8 6.8 0.1 3.3 4 0 0 4 4 4 0 Tetratricopeptide repeat AAA_6 PF12774.7 CBZ30501.1 - 1.5e-152 507.3 0.0 5.3e-152 505.5 0.0 2.1 2 0 0 2 2 2 1 Hydrolytic ATP binding site of dynein motor region DHC_N1 PF08385.12 CBZ30501.1 - 6.6e-134 447.6 0.7 6.6e-134 447.6 0.7 3.1 3 0 0 3 3 3 1 Dynein heavy chain, N-terminal region 1 DHC_N2 PF08393.13 CBZ30501.1 - 2e-113 379.5 10.1 2e-113 379.5 10.1 4.9 7 0 0 7 7 6 1 Dynein heavy chain, N-terminal region 2 AAA_8 PF12780.7 CBZ30501.1 - 4.1e-101 337.7 0.0 1.1e-100 336.3 0.0 1.8 1 0 0 1 1 1 1 P-loop containing dynein motor region D4 Dynein_C PF18199.1 CBZ30501.1 - 4.2e-79 266.0 0.3 4.2e-79 266.0 0.3 2.2 2 0 0 2 2 2 1 Dynein heavy chain C-terminal domain AAA_9 PF12781.7 CBZ30501.1 - 5.9e-75 251.2 0.0 5.9e-75 251.2 0.0 3.4 4 0 0 4 4 3 1 ATP-binding dynein motor region AAA_7 PF12775.7 CBZ30501.1 - 2.7e-65 219.3 5.1 1.4e-45 155.1 0.0 4.9 5 0 0 5 5 5 3 P-loop containing dynein motor region AAA_lid_11 PF18198.1 CBZ30501.1 - 7.6e-50 168.9 0.1 2.2e-49 167.4 0.1 1.9 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain Dynein_heavy PF03028.15 CBZ30501.1 - 3.8e-43 146.4 0.1 9.4e-42 141.9 0.1 3.0 2 0 0 2 2 2 1 Dynein heavy chain region D6 P-loop domain MT PF12777.7 CBZ30501.1 - 1.1e-41 143.0 8.0 1.9e-41 142.2 8.0 1.4 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_5 PF07728.14 CBZ30501.1 - 1.9e-21 76.5 0.3 2.4e-07 30.8 0.0 6.9 5 2 0 5 5 5 3 AAA domain (dynein-related subfamily) Dynein_AAA_lid PF17852.1 CBZ30501.1 - 5.1e-21 75.1 0.2 2.9e-20 72.6 0.0 2.5 2 0 0 2 2 2 1 Dynein heavy chain AAA lid domain AAA_lid_1 PF17857.1 CBZ30501.1 - 3.7e-15 56.0 0.0 1.6e-14 53.9 0.0 2.2 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 CBZ30501.1 - 4.3e-09 37.0 2.2 0.095 13.1 0.0 6.6 5 0 0 5 5 5 1 AAA ATPase domain AAA PF00004.29 CBZ30501.1 - 3.1e-07 30.9 3.4 0.68 10.4 0.0 6.5 6 0 0 6 6 5 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 CBZ30501.1 - 6.7e-05 23.2 4.8 0.89 9.8 0.0 5.4 5 0 0 5 5 3 2 AAA domain AAA_18 PF13238.6 CBZ30501.1 - 0.00033 21.2 0.2 4.1 7.9 0.0 4.9 4 0 0 4 4 3 1 AAA domain RsgA_GTPase PF03193.16 CBZ30501.1 - 0.00073 19.5 1.4 0.027 14.4 0.1 3.4 3 0 0 3 3 3 1 RsgA GTPase AAA_33 PF13671.6 CBZ30501.1 - 0.001 19.2 5.3 0.83 9.8 0.0 5.3 6 0 0 6 6 5 1 AAA domain AAA_29 PF13555.6 CBZ30501.1 - 0.0026 17.5 0.2 0.085 12.6 0.0 2.7 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_30 PF13604.6 CBZ30501.1 - 0.0065 16.2 3.4 3 7.5 0.1 4.1 4 0 0 4 4 4 1 AAA domain ABC_tran PF00005.27 CBZ30501.1 - 0.0074 16.8 2.1 1.4 9.5 0.0 4.2 3 0 0 3 3 2 1 ABC transporter Rad17 PF03215.15 CBZ30501.1 - 0.016 15.1 0.6 2.4 8.0 0.0 3.3 3 0 0 3 3 2 0 Rad17 P-loop domain RNA_helicase PF00910.22 CBZ30501.1 - 0.038 14.4 2.3 2.7 8.4 0.0 3.5 3 0 0 3 3 3 0 RNA helicase COG5 PF10392.9 CBZ30501.1 - 0.05 13.8 1.5 1.6 8.9 0.9 3.7 2 0 0 2 2 2 0 Golgi transport complex subunit 5 DUF1612 PF07756.12 CBZ30501.1 - 0.29 11.4 4.8 1.1 9.5 4.8 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1612) Carla_C4 PF01623.17 CBZ30501.1 - 0.6 10.1 1.9 2.9 7.9 0.1 2.5 2 0 0 2 2 2 0 Carlavirus putative nucleic acid binding protein T2SSE PF00437.20 CBZ30501.1 - 4.3 6.3 8.4 2.8 6.9 0.1 3.9 4 0 0 4 4 4 0 Type II/IV secretion system protein HATPase_c PF02518.26 CBZ30503.1 - 1.1e-10 42.0 0.0 3e-10 40.6 0.0 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Pet191_N PF10203.9 CBZ30504.1 - 3.5e-09 36.8 2.6 5.1e-09 36.3 2.6 1.3 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein PET191 AFP PF02420.15 CBZ30504.1 - 0.09 13.2 2.3 2.9 8.5 0.2 2.5 2 0 0 2 2 2 0 Insect antifreeze protein repeat NIF PF03031.18 CBZ30505.1 - 8.6e-26 90.6 0.0 1.3e-25 90.0 0.0 1.3 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase DUF705 PF05152.12 CBZ30505.1 - 1.4e-05 24.8 0.0 2e-05 24.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF705) LBP_BPI_CETP_C PF02886.17 CBZ30506.1 - 0.081 12.4 0.4 0.53 9.7 0.0 2.4 3 0 0 3 3 3 0 LBP / BPI / CETP family, C-terminal domain LPAM_1 PF08139.12 CBZ30506.1 - 0.2 12.2 0.4 0.51 10.9 0.4 1.7 1 0 0 1 1 1 0 Prokaryotic membrane lipoprotein lipid attachment site PI3_PI4_kinase PF00454.27 CBZ30507.1 - 7.7e-57 193.0 0.0 2.5e-56 191.3 0.0 2.0 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FAT PF02259.23 CBZ30507.1 - 7.2e-22 78.1 0.1 1.5e-21 77.0 0.1 1.6 1 0 0 1 1 1 1 FAT domain FRB_dom PF08771.11 CBZ30507.1 - 1.4e-14 54.2 0.5 1e-13 51.5 0.5 2.6 1 0 0 1 1 1 1 FKBP12-rapamycin binding domain DUF3385 PF11865.8 CBZ30507.1 - 2e-13 50.6 5.4 5.5e-13 49.1 0.4 3.1 3 0 0 3 3 3 1 Domain of unknown function (DUF3385) FATC PF02260.20 CBZ30507.1 - 2.6e-11 43.1 0.4 1.2e-10 41.0 0.0 2.2 2 0 0 2 2 2 1 FATC domain PDZ_6 PF17820.1 CBZ30507.1 - 0.00026 20.8 0.1 0.00069 19.4 0.1 1.8 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 CBZ30507.1 - 0.00049 20.4 0.1 0.0011 19.2 0.1 1.5 1 0 0 1 1 1 1 PDZ domain PUF PF00806.19 CBZ30507.1 - 0.24 11.2 0.5 29 4.6 0.0 3.3 3 0 0 3 3 3 0 Pumilio-family RNA binding repeat DivIC PF04977.15 CBZ30508.1 - 0.011 15.5 0.7 0.017 14.9 0.7 1.2 1 0 0 1 1 1 0 Septum formation initiator UPF0184 PF03670.13 CBZ30508.1 - 0.052 13.9 0.2 0.097 13.1 0.2 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0184) PIG-Y PF15159.6 CBZ30509.1 - 4.4e-07 30.7 6.3 5.9e-07 30.3 6.3 1.1 1 0 0 1 1 1 1 Phosphatidylinositol N-acetylglucosaminyltransferase subunit Y PIG-Y PF15159.6 CBZ30510.1 - 1.5e-09 38.6 5.4 1.8e-09 38.4 5.4 1.2 1 0 0 1 1 1 1 Phosphatidylinositol N-acetylglucosaminyltransferase subunit Y ABG_transport PF03806.13 CBZ30510.1 - 0.01 14.1 0.3 0.011 14.0 0.3 1.0 1 0 0 1 1 1 0 AbgT putative transporter family HECT PF00632.25 CBZ30511.1 - 6.2e-48 163.8 0.0 1.6e-47 162.5 0.0 1.6 1 1 0 1 1 1 1 HECT-domain (ubiquitin-transferase) DCB PF16213.5 CBZ30511.1 - 0.1 12.2 1.1 0.27 10.9 1.1 1.7 1 0 0 1 1 1 0 Dimerisation and cyclophilin-binding domain of Mon2 Adaptin_N PF01602.20 CBZ30512.1 - 4.3e-73 246.6 9.6 5.9e-73 246.2 9.6 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptinC2 PF02883.20 CBZ30512.1 - 1.5e-10 41.4 0.0 3.5e-10 40.2 0.0 1.5 1 0 0 1 1 1 1 Adaptin C-terminal domain Vac14_Fab1_bd PF12755.7 CBZ30512.1 - 0.044 14.4 1.1 1.7 9.3 0.0 3.4 2 1 0 3 3 3 0 Vacuolar 14 Fab1-binding region Telomere_reg-2 PF10193.9 CBZ30512.1 - 1.3 9.5 6.9 0.34 11.4 0.2 3.1 4 0 0 4 4 4 0 Telomere length regulation protein Ribosomal_L7Ae PF01248.26 CBZ30513.1 - 1.3e-19 69.7 0.3 1.5e-19 69.5 0.3 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Rgp1 PF08737.10 CBZ30514.1 - 2.3e-08 33.6 0.1 0.0056 15.9 0.0 2.2 2 0 0 2 2 2 2 Rgp1 Peptidase_C78 PF07910.13 CBZ30515.1 - 6.4e-49 166.3 0.0 1.1e-48 165.5 0.0 1.4 1 0 0 1 1 1 1 Peptidase family C78 Peptidase_C54 PF03416.19 CBZ30515.1 - 0.048 13.1 0.0 0.39 10.1 0.0 2.1 2 0 0 2 2 2 0 Peptidase family C54 PAC3 PF10178.9 CBZ30515.1 - 0.14 12.4 0.0 0.32 11.2 0.0 1.5 1 0 0 1 1 1 0 Proteasome assembly chaperone 3 FANCI_S1-cap PF14674.6 CBZ30517.1 - 0.019 15.0 0.6 0.57 10.3 0.1 2.4 2 0 0 2 2 2 0 FANCI solenoid 1 cap DUF445 PF04286.12 CBZ30517.1 - 0.082 12.7 3.4 0.11 12.3 3.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF445) HrpB_C PF08482.10 CBZ30517.1 - 0.09 13.2 0.3 0.2 12.0 0.0 1.7 2 0 0 2 2 2 0 ATP-dependent helicase C-terminal U3snoRNP10 PF12397.8 CBZ30517.1 - 2.3 8.6 5.7 1.8 9.0 1.3 2.9 2 1 1 3 3 3 0 U3 small nucleolar RNA-associated protein 10 Prenyltrans PF00432.21 CBZ30518.1 - 7.5e-71 233.5 17.1 1.2e-14 53.7 0.4 6.0 6 0 0 6 6 6 5 Prenyltransferase and squalene oxidase repeat SQHop_cyclase_N PF13249.6 CBZ30518.1 - 6.9e-09 35.2 0.0 0.021 14.0 0.0 4.3 1 1 3 4 4 4 3 Squalene-hopene cyclase N-terminal domain SQHop_cyclase_C PF13243.6 CBZ30518.1 - 0.00011 21.4 0.9 0.0033 16.6 0.0 2.8 1 1 3 4 4 4 1 Squalene-hopene cyclase C-terminal domain TED_complement PF07678.14 CBZ30518.1 - 0.12 11.4 0.1 1 8.3 0.0 2.6 3 1 1 4 4 4 0 A-macroglobulin TED domain UCH PF00443.29 CBZ30521.1 - 7.9e-37 127.1 0.1 1.2e-36 126.6 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 CBZ30521.1 - 3.3e-13 49.9 0.1 1.1e-12 48.2 0.1 1.8 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Peptidase_C98 PF15499.6 CBZ30521.1 - 0.069 12.6 0.9 0.11 11.9 0.1 1.7 2 0 0 2 2 2 0 Ubiquitin-specific peptidase-like, SUMO isopeptidase RWP-RK PF02042.15 CBZ30521.1 - 0.13 12.2 0.1 2.8 8.0 0.0 2.6 2 0 0 2 2 2 0 RWP-RK domain Casc1_N PF15927.5 CBZ30522.1 - 1.4e-11 44.4 7.0 3.7e-11 43.1 7.0 1.7 1 1 0 1 1 1 1 Cancer susceptibility candidate 1 N-terminus Herpes_HEPA PF03324.14 CBZ30522.1 - 0.11 13.0 0.0 0.63 10.5 0.0 2.2 2 0 0 2 2 2 0 Herpesvirus DNA helicase/primase complex associated protein PVL_ORF50 PF07768.11 CBZ30522.1 - 0.74 10.1 4.9 1.9 8.9 4.9 1.6 1 0 0 1 1 1 0 PVL ORF-50-like family DnaJ PF00226.31 CBZ30523.1 - 2.2e-06 27.7 0.5 6.6e-06 26.2 0.1 1.9 2 1 0 2 2 2 1 DnaJ domain GRIP PF01465.20 CBZ30524.1 - 8.1e-11 41.6 0.2 8.1e-11 41.6 0.2 2.3 3 0 0 3 3 2 1 GRIP domain Prominin PF05478.11 CBZ30524.1 - 0.002 16.2 6.5 0.0029 15.6 6.5 1.1 1 0 0 1 1 1 1 Prominin V_ATPase_I PF01496.19 CBZ30524.1 - 0.017 13.1 4.0 0.022 12.7 4.0 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF4715 PF15835.5 CBZ30524.1 - 0.021 14.9 0.2 0.021 14.9 0.2 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4715) GAS PF13851.6 CBZ30524.1 - 0.06 12.7 32.5 0.86 8.9 0.1 3.2 3 0 0 3 3 3 0 Growth-arrest specific micro-tubule binding Herpes_UL6 PF01763.16 CBZ30524.1 - 0.13 10.8 5.9 0.2 10.1 5.9 1.2 1 0 0 1 1 1 0 Herpesvirus UL6 like MPS2 PF17060.5 CBZ30524.1 - 0.21 10.8 9.3 0.019 14.2 3.7 2.1 2 1 0 2 2 2 0 Monopolar spindle protein 2 ATG16 PF08614.11 CBZ30524.1 - 0.82 9.9 35.3 0.57 10.4 25.8 3.0 2 1 1 3 3 3 0 Autophagy protein 16 (ATG16) SPATA9 PF15824.5 CBZ30524.1 - 1.1 8.5 6.8 0.35 10.1 3.6 1.7 2 0 0 2 2 2 0 Spermatogenesis-associated protein 9 dCache_2 PF08269.11 CBZ30524.1 - 1.4 8.0 6.9 0.51 9.5 4.1 1.6 1 1 0 1 1 1 0 Cache domain Baculo_PEP_C PF04513.12 CBZ30524.1 - 1.8 8.6 10.0 2.4 8.2 6.7 2.9 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF2477 PF10631.9 CBZ30524.1 - 1.9 9.1 4.7 0.81 10.3 0.6 2.4 2 1 0 3 3 3 0 Protein of unknown function (DUF2477) Phlebovirus_NSM PF07246.11 CBZ30524.1 - 2.5 7.4 10.3 0.17 11.2 4.9 1.8 2 0 0 2 2 2 0 Phlebovirus nonstructural protein NS-M HALZ PF02183.18 CBZ30524.1 - 5.4 7.3 15.0 0.83 9.9 0.2 4.2 3 1 1 4 4 4 0 Homeobox associated leucine zipper Peptidase_C50 PF03568.17 CBZ30526.1 - 0.036 13.2 0.1 0.13 11.3 0.0 1.9 2 0 0 2 2 2 0 Peptidase family C50 Abhydrolase_6 PF12697.7 CBZ30527.1 - 0.00026 21.7 0.4 0.00033 21.3 0.4 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 CBZ30527.1 - 0.00042 19.7 0.0 0.0006 19.1 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 CBZ30527.1 - 0.00051 19.8 0.0 0.0096 15.6 0.0 2.0 1 1 0 2 2 2 1 alpha/beta hydrolase fold EMC1_C PF07774.13 CBZ30528.1 - 8.2e-48 162.9 0.0 1.8e-47 161.8 0.0 1.6 1 0 0 1 1 1 1 ER membrane protein complex subunit 1, C-terminal PQQ_3 PF13570.6 CBZ30528.1 - 0.00073 19.9 7.0 0.24 11.9 0.2 4.4 4 0 0 4 4 4 2 PQQ-like domain DCB PF16213.5 CBZ30528.1 - 0.094 12.4 0.0 0.17 11.5 0.0 1.4 1 0 0 1 1 1 0 Dimerisation and cyclophilin-binding domain of Mon2 E2F_CC-MB PF16421.5 CBZ30528.1 - 0.12 12.7 0.0 3.2 8.2 0.0 2.5 2 1 0 2 2 2 0 E2F transcription factor CC-MB domain DUF4743 PF15916.5 CBZ30529.1 - 0.27 11.2 2.2 0.25 11.3 0.4 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4743) REPA_OB_2 PF16900.5 CBZ30530.1 - 0.038 13.9 0.0 0.07 13.1 0.0 1.4 1 0 0 1 1 1 0 Replication protein A OB domain AAA_6 PF12774.7 CBZ30531.1 - 8.4e-128 425.9 0.1 4.7e-127 423.5 0.0 2.4 2 0 0 2 2 2 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 CBZ30531.1 - 8.8e-107 357.6 3.5 8.8e-107 357.6 3.5 5.4 3 2 1 4 4 4 1 Dynein heavy chain, N-terminal region 2 AAA_9 PF12781.7 CBZ30531.1 - 5.2e-65 218.7 0.3 5.2e-65 218.7 0.3 3.8 4 0 0 4 4 2 1 ATP-binding dynein motor region AAA_8 PF12780.7 CBZ30531.1 - 6.6e-45 153.5 3.1 1.5e-43 149.0 0.0 3.4 3 0 0 3 3 3 1 P-loop containing dynein motor region D4 DHC_N1 PF08385.12 CBZ30531.1 - 4.2e-38 131.3 6.8 1.1e-37 129.9 0.0 4.4 5 0 0 5 5 5 1 Dynein heavy chain, N-terminal region 1 AAA_5 PF07728.14 CBZ30531.1 - 8.6e-34 116.5 0.0 2.6e-21 76.1 0.0 5.5 4 1 0 4 4 4 3 AAA domain (dynein-related subfamily) AAA_7 PF12775.7 CBZ30531.1 - 1.1e-31 109.8 0.2 1.6e-25 89.7 0.0 4.8 4 0 0 4 4 4 2 P-loop containing dynein motor region Dynein_heavy PF03028.15 CBZ30531.1 - 5.5e-30 103.9 0.0 1.4e-28 99.3 0.0 3.5 3 0 0 3 3 2 1 Dynein heavy chain region D6 P-loop domain AAA_lid_11 PF18198.1 CBZ30531.1 - 6.5e-29 100.8 0.0 1.4e-28 99.7 0.0 1.6 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain MT PF12777.7 CBZ30531.1 - 7e-26 91.1 10.4 1.9e-25 89.7 10.4 1.8 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor Dynein_C PF18199.1 CBZ30531.1 - 1.9e-24 86.5 0.2 8.8e-24 84.3 0.0 2.3 2 0 0 2 2 1 1 Dynein heavy chain C-terminal domain AAA_16 PF13191.6 CBZ30531.1 - 2.2e-15 57.5 0.4 9.3e-06 26.1 0.0 6.2 5 0 0 5 5 3 2 AAA ATPase domain AAA_22 PF13401.6 CBZ30531.1 - 1.9e-11 44.4 0.6 0.00082 19.7 0.0 4.7 4 0 0 4 4 3 2 AAA domain AAA PF00004.29 CBZ30531.1 - 4e-11 43.5 0.0 0.029 14.8 0.0 4.5 3 0 0 3 3 3 3 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 CBZ30531.1 - 1.8e-07 31.1 0.0 0.0018 18.0 0.0 3.8 3 0 0 3 3 3 1 AAA domain RNA_helicase PF00910.22 CBZ30531.1 - 6e-07 29.8 0.0 0.23 11.8 0.0 3.7 3 0 0 3 3 3 1 RNA helicase AAA_24 PF13479.6 CBZ30531.1 - 1.5e-06 28.1 0.0 0.11 12.1 0.0 3.8 3 0 0 3 3 3 1 AAA domain RsgA_GTPase PF03193.16 CBZ30531.1 - 4.3e-06 26.7 2.3 0.00076 19.4 0.0 3.2 3 0 0 3 3 2 1 RsgA GTPase AAA_33 PF13671.6 CBZ30531.1 - 8.6e-06 26.0 0.0 0.088 13.0 0.0 3.8 3 0 0 3 3 3 2 AAA domain IstB_IS21 PF01695.17 CBZ30531.1 - 3.2e-05 23.8 0.2 0.11 12.2 0.0 4.4 4 0 0 4 4 4 1 IstB-like ATP binding protein AAA_28 PF13521.6 CBZ30531.1 - 4.5e-05 23.8 4.7 0.3 11.3 0.0 4.9 6 0 0 6 6 3 1 AAA domain AAA_18 PF13238.6 CBZ30531.1 - 8.7e-05 23.1 4.5 0.066 13.8 0.0 5.4 5 0 0 5 5 5 1 AAA domain Fez1 PF06818.15 CBZ30531.1 - 0.00014 22.4 4.0 0.00014 22.4 4.0 5.1 5 0 0 5 5 3 1 Fez1 ABC_tran PF00005.27 CBZ30531.1 - 0.00023 21.7 10.9 0.0044 17.5 0.0 4.4 5 0 0 5 5 2 2 ABC transporter AAA_14 PF13173.6 CBZ30531.1 - 0.00027 21.0 0.5 0.17 11.9 0.0 4.0 4 0 0 4 4 3 1 AAA domain Sigma54_activat PF00158.26 CBZ30531.1 - 0.00052 19.8 0.0 0.15 11.8 0.0 2.6 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_29 PF13555.6 CBZ30531.1 - 0.00072 19.2 0.6 0.037 13.8 0.0 3.0 3 0 0 3 3 2 1 P-loop containing region of AAA domain NACHT PF05729.12 CBZ30531.1 - 0.00075 19.5 4.4 0.37 10.7 0.0 3.4 4 0 0 4 4 2 2 NACHT domain TsaE PF02367.17 CBZ30531.1 - 0.0009 19.2 0.0 0.49 10.4 0.0 4.0 4 0 0 4 4 3 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_25 PF13481.6 CBZ30531.1 - 0.0016 18.1 0.6 2.3 7.7 0.0 4.2 4 0 0 4 4 3 1 AAA domain cobW PF02492.19 CBZ30531.1 - 0.0019 17.8 0.4 0.92 9.1 0.0 3.1 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain SRPRB PF09439.10 CBZ30531.1 - 0.002 17.6 3.1 0.023 14.2 0.0 3.3 3 0 0 3 3 3 1 Signal recognition particle receptor beta subunit CbiA PF01656.23 CBZ30531.1 - 0.0022 18.1 0.0 11 6.1 0.0 4.0 3 0 0 3 3 3 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_21 PF13304.6 CBZ30531.1 - 0.0025 17.7 0.1 0.018 14.8 0.0 2.5 3 0 0 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system Rad17 PF03215.15 CBZ30531.1 - 0.0028 17.6 0.3 0.87 9.5 0.0 3.5 3 0 0 3 3 3 1 Rad17 P-loop domain T2SSE PF00437.20 CBZ30531.1 - 0.0034 16.5 0.0 0.22 10.5 0.0 2.9 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_lid_7 PF17867.1 CBZ30531.1 - 0.0053 16.9 2.3 0.041 14.1 0.0 3.7 4 0 0 4 4 2 1 Midasin AAA lid domain Mg_chelatase PF01078.21 CBZ30531.1 - 0.0055 16.1 0.1 6.9 6.0 0.0 3.3 3 0 0 3 3 2 0 Magnesium chelatase, subunit ChlI MeaB PF03308.16 CBZ30531.1 - 0.0057 15.7 0.3 0.2 10.6 0.0 2.8 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB Roc PF08477.13 CBZ30531.1 - 0.0069 16.6 0.1 3.1 8.1 0.0 3.1 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 CBZ30531.1 - 0.018 15.1 0.2 2.5 8.2 0.0 3.1 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_PrkA PF08298.11 CBZ30531.1 - 0.019 13.9 0.0 0.061 12.2 0.0 1.8 2 0 0 2 2 1 0 PrkA AAA domain ATP_bind_1 PF03029.17 CBZ30531.1 - 0.027 14.3 1.1 1.7 8.4 0.0 3.7 3 0 0 3 3 2 0 Conserved hypothetical ATP binding protein Zeta_toxin PF06414.12 CBZ30531.1 - 0.031 13.5 0.0 1.4 8.1 0.0 3.4 4 0 0 4 4 3 0 Zeta toxin Septin PF00735.18 CBZ30531.1 - 0.05 12.9 0.4 5.7 6.1 0.0 2.8 3 0 0 3 3 2 0 Septin IIGP PF05049.13 CBZ30531.1 - 0.061 12.4 0.0 0.061 12.4 0.0 2.6 3 0 0 3 3 2 0 Interferon-inducible GTPase (IIGP) Guanylate_kin PF00625.21 CBZ30531.1 - 0.076 12.7 8.2 0.35 10.5 0.0 4.1 4 0 0 4 4 3 0 Guanylate kinase NB-ARC PF00931.22 CBZ30531.1 - 0.082 12.1 2.8 2.2 7.4 0.0 3.6 4 0 0 4 4 3 0 NB-ARC domain ATPase_2 PF01637.18 CBZ30531.1 - 0.12 12.3 14.9 0.21 11.5 0.0 4.3 5 0 0 5 5 3 0 ATPase domain predominantly from Archaea DXP_reductoisom PF02670.16 CBZ30531.1 - 0.16 12.7 1.2 0.87 10.3 0.0 3.0 3 0 0 3 3 1 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase Cytidylate_kin PF02224.18 CBZ30531.1 - 0.22 11.2 6.4 4.6 6.9 0.0 3.7 3 0 0 3 3 3 0 Cytidylate kinase DUF2666 PF10869.8 CBZ30531.1 - 0.39 10.9 0.0 0.39 10.9 0.0 3.9 4 0 0 4 4 3 0 Protein of unknown function (DUF2666) AAA_23 PF13476.6 CBZ30531.1 - 0.53 10.8 0.0 0.53 10.8 0.0 7.5 7 0 0 7 7 7 0 AAA domain Laminin_II PF06009.12 CBZ30531.1 - 0.59 10.2 23.3 0.0047 16.9 2.5 4.9 5 0 0 5 5 3 0 Laminin Domain II Goodbye PF17109.5 CBZ30531.1 - 7.6 7.0 11.0 0.88 10.0 0.2 3.9 4 0 0 4 4 2 0 fungal STAND N-terminal Goodbye domain zf-CCHC_3 PF13917.6 CBZ30532.1 - 6.5e-14 51.6 2.1 1.1e-13 50.8 2.1 1.4 1 0 0 1 1 1 1 Zinc knuckle eIF3g PF12353.8 CBZ30532.1 - 0.0017 18.7 0.7 0.0017 18.7 0.7 2.0 2 0 0 2 2 2 1 Eukaryotic translation initiation factor 3 subunit G TRAUB PF08164.12 CBZ30532.1 - 0.049 14.1 0.4 0.12 12.9 0.2 1.8 1 1 0 1 1 1 0 Apoptosis-antagonizing transcription factor, C-terminal zf-CCHC PF00098.23 CBZ30532.1 - 0.075 13.1 0.2 0.15 12.2 0.2 1.5 1 0 0 1 1 1 0 Zinc knuckle Fam20C PF06702.12 CBZ30533.1 - 2.4e-05 24.2 0.0 0.075 12.9 0.0 2.3 2 0 0 2 2 2 2 Golgi casein kinase, C-terminal, Fam20 HipA_C PF07804.12 CBZ30533.1 - 0.069 12.8 0.0 0.38 10.4 0.0 2.1 1 1 0 1 1 1 0 HipA-like C-terminal domain Metallophos PF00149.28 CBZ30534.1 - 2.6e-33 116.2 0.0 3.6e-33 115.8 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase HTH_Tnp_ISL3 PF13542.6 CBZ30536.1 - 0.04 13.3 0.1 0.11 12.0 0.1 1.8 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 MarR_2 PF12802.7 CBZ30536.1 - 0.61 10.0 2.6 5.5 7.0 0.1 2.5 2 0 0 2 2 2 0 MarR family Complex1_LYR PF05347.15 CBZ30537.1 - 0.031 14.3 0.1 0.073 13.1 0.1 1.7 1 0 0 1 1 1 0 Complex 1 protein (LYR family) Robl_LC7 PF03259.17 CBZ30538.1 - 0.011 15.5 0.0 0.019 14.7 0.0 1.5 1 1 0 1 1 1 0 Roadblock/LC7 domain BRCT PF00533.26 CBZ30539.1 - 2e-08 34.5 0.0 1.3e-06 28.6 0.0 2.7 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain FHA PF00498.26 CBZ30539.1 - 6.3e-07 29.7 0.0 1.2e-06 28.8 0.0 1.5 1 0 0 1 1 1 1 FHA domain RTT107_BRCT_5 PF16770.5 CBZ30539.1 - 1.1e-05 25.2 0.0 2.2e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 Regulator of Ty1 transposition protein 107 BRCT domain BRCT_2 PF16589.5 CBZ30539.1 - 1.7e-05 25.1 0.0 0.066 13.6 0.0 2.7 3 0 0 3 3 3 2 BRCT domain, a BRCA1 C-terminus domain PTCB-BRCT PF12738.7 CBZ30539.1 - 6.9e-05 22.7 0.0 0.00022 21.1 0.0 1.9 2 0 0 2 2 2 1 twin BRCT domain Glycos_trans_3N PF02885.17 CBZ30539.1 - 0.15 11.9 0.3 50 3.8 0.1 3.4 3 0 0 3 3 3 0 Glycosyl transferase family, helical bundle domain SLD3 PF08639.10 CBZ30540.1 - 0.1 11.4 0.3 0.16 10.7 0.3 1.3 1 0 0 1 1 1 0 DNA replication regulator SLD3 KASH PF10541.9 CBZ30540.1 - 0.1 12.9 0.6 8.7 6.7 0.1 3.1 2 1 1 3 3 3 0 Nuclear envelope localisation domain SR-25 PF10500.9 CBZ30540.1 - 2.6 7.6 7.0 4.8 6.7 7.0 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Kinesin PF00225.23 CBZ30541.1 - 3.4e-104 348.4 0.1 5.8e-104 347.6 0.1 1.4 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 CBZ30541.1 - 1.6e-16 60.5 0.0 3.6e-16 59.4 0.0 1.5 1 0 0 1 1 1 1 Microtubule binding Pex24p PF06398.11 CBZ30541.1 - 6.1e-05 22.2 2.5 0.00011 21.3 2.5 1.4 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin Spc7 PF08317.11 CBZ30541.1 - 0.065 12.1 18.2 0.1 11.5 18.2 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein Fib_alpha PF08702.10 CBZ30541.1 - 0.073 13.3 6.5 0.16 12.2 6.0 1.9 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family DUF1495 PF07381.11 CBZ30541.1 - 0.1 12.4 0.1 0.39 10.6 0.1 1.9 2 0 0 2 2 2 0 Winged helix DNA-binding domain (DUF1495) SlyX PF04102.12 CBZ30541.1 - 7.9 7.2 13.4 0.28 11.8 1.3 3.2 3 0 0 3 3 3 0 SlyX Cullin_binding PF03556.15 CBZ30542.1 - 2.6e-16 60.1 0.5 4.7e-16 59.3 0.5 1.3 1 0 0 1 1 1 1 Cullin binding Ank_2 PF12796.7 CBZ30543.1 - 1.4e-18 67.2 2.4 3.3e-10 40.4 0.1 3.5 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CBZ30543.1 - 1.6e-17 63.6 2.5 8.5e-06 26.2 0.1 4.5 2 1 3 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 CBZ30543.1 - 2.3e-13 49.0 1.6 0.016 15.7 0.0 4.9 4 0 0 4 4 4 4 Ankyrin repeat Ank PF00023.30 CBZ30543.1 - 8.1e-11 41.9 3.8 0.033 14.7 0.1 4.8 4 0 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.6 CBZ30543.1 - 9.6e-11 41.7 11.7 0.00014 22.1 0.7 5.0 2 1 2 5 5 5 4 Ankyrin repeats (many copies) CMV_1a PF12467.8 CBZ30543.1 - 0.16 12.3 0.4 0.34 11.2 0.4 1.4 1 0 0 1 1 1 0 Cucumber mosaic virus 1a protein family Gar1 PF04410.14 CBZ30544.1 - 3.5e-27 95.1 0.0 4.4e-27 94.8 0.0 1.0 1 0 0 1 1 1 1 Gar1/Naf1 RNA binding region DHHC PF01529.20 CBZ30545.1 - 9.7e-16 58.1 3.3 9.7e-16 58.1 3.3 2.0 2 0 0 2 2 2 1 DHHC palmitoyltransferase Cys_knot PF00007.22 CBZ30545.1 - 0.02 15.2 0.8 0.038 14.3 0.8 1.4 1 0 0 1 1 1 0 Cystine-knot domain DUF2070 PF09843.9 CBZ30545.1 - 5.2 5.2 7.1 6.6 4.9 7.1 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) Coatomer_WDAD PF04053.14 CBZ30546.1 - 1.3e-97 327.6 0.1 1.9e-97 327.1 0.1 1.2 1 0 0 1 1 1 1 Coatomer WD associated region COPI_C PF06957.11 CBZ30546.1 - 1.4e-97 327.1 0.0 2.1e-97 326.4 0.0 1.1 1 0 0 1 1 1 1 Coatomer (COPI) alpha subunit C-terminus WD40 PF00400.32 CBZ30546.1 - 4.9e-40 134.8 20.8 3.6e-07 30.8 0.2 7.3 7 0 0 7 7 7 6 WD domain, G-beta repeat HSDR_N PF04313.14 CBZ30546.1 - 0.024 14.6 0.0 0.051 13.5 0.0 1.5 1 0 0 1 1 1 0 Type I restriction enzyme R protein N terminus (HSDR_N) TPR_14 PF13428.6 CBZ30546.1 - 0.071 14.0 5.8 16 6.7 0.5 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat ESSS PF10183.9 CBZ30547.1 - 1e-16 61.0 7.7 2e-16 60.1 7.7 1.6 1 1 0 1 1 1 1 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) adh_short PF00106.25 CBZ30548.1 - 1.1e-12 47.9 1.0 4e-12 46.0 1.0 1.8 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CBZ30548.1 - 3.5e-08 33.3 2.8 8.1e-08 32.1 2.8 1.5 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Sacchrp_dh_NADP PF03435.18 CBZ30548.1 - 0.0019 18.4 0.4 0.0042 17.3 0.4 1.6 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Epimerase PF01370.21 CBZ30548.1 - 0.013 15.0 0.2 0.041 13.3 0.2 1.8 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 CBZ30548.1 - 0.035 13.2 0.2 0.075 12.1 0.1 1.6 2 0 0 2 2 2 0 RmlD substrate binding domain Proteasome PF00227.26 CBZ30549.1 - 5.2e-28 97.8 0.0 5.9e-28 97.6 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit PI3_PI4_kinase PF00454.27 CBZ30550.1 - 3.1e-58 197.5 0.1 9.2e-58 196.0 0.1 1.8 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FAT PF02259.23 CBZ30550.1 - 1.3e-40 139.7 1.1 5.1e-40 137.8 1.1 2.0 1 1 0 1 1 1 1 FAT domain FRB_dom PF08771.11 CBZ30550.1 - 5.5e-28 97.3 0.2 2.4e-27 95.2 0.2 2.2 1 0 0 1 1 1 1 FKBP12-rapamycin binding domain DUF3385 PF11865.8 CBZ30550.1 - 2.6e-15 56.7 0.0 3.3e-14 53.1 0.0 2.9 3 0 0 3 3 3 1 Domain of unknown function (DUF3385) FATC PF02260.20 CBZ30550.1 - 2.9e-11 43.0 0.4 1e-10 41.3 0.4 2.0 1 0 0 1 1 1 1 FATC domain HEAT PF02985.22 CBZ30550.1 - 0.00063 19.8 5.0 3.4 8.2 0.0 6.9 7 0 0 7 7 7 1 HEAT repeat Cnd1 PF12717.7 CBZ30550.1 - 0.0017 18.5 0.3 0.44 10.6 0.0 4.4 3 1 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 CBZ30550.1 - 0.0077 16.6 0.0 2.3 8.7 0.0 4.8 4 0 0 4 4 4 1 HEAT repeats HEAT_EZ PF13513.6 CBZ30550.1 - 0.039 14.5 1.0 6.5 7.4 0.0 4.7 5 0 0 5 5 5 0 HEAT-like repeat ParcG PF10274.9 CBZ30550.1 - 0.16 12.1 0.6 2.5 8.2 0.0 3.2 4 0 0 4 4 4 0 Parkin co-regulated protein ADIP PF11559.8 CBZ30551.1 - 0.00085 19.4 5.7 0.00098 19.2 5.7 1.1 1 0 0 1 1 1 1 Afadin- and alpha -actinin-Binding IFT57 PF10498.9 CBZ30551.1 - 0.005 15.9 3.7 0.005 15.9 3.7 1.1 1 0 0 1 1 1 1 Intra-flagellar transport protein 57 JAKMIP_CC3 PF16034.5 CBZ30551.1 - 0.014 15.4 2.6 0.018 15.0 2.6 1.3 1 0 0 1 1 1 0 JAKMIP CC3 domain Lebercilin PF15619.6 CBZ30551.1 - 0.017 14.8 8.5 0.036 13.7 8.5 1.6 1 1 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease FAM76 PF16046.5 CBZ30551.1 - 0.021 14.2 3.8 0.024 14.0 3.8 1.1 1 0 0 1 1 1 0 FAM76 protein DUF4061 PF13270.6 CBZ30551.1 - 0.021 15.1 1.3 0.065 13.6 1.5 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4061) SKA1 PF07160.12 CBZ30551.1 - 0.032 14.1 2.5 0.044 13.6 2.3 1.4 1 1 0 1 1 1 0 Spindle and kinetochore-associated protein 1 BRE1 PF08647.11 CBZ30551.1 - 0.039 14.0 7.7 0.078 13.0 7.7 1.6 1 1 0 1 1 1 0 BRE1 E3 ubiquitin ligase DUF3450 PF11932.8 CBZ30551.1 - 0.04 13.2 7.0 0.034 13.5 6.1 1.4 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) HMMR_C PF15908.5 CBZ30551.1 - 0.043 14.1 2.4 0.071 13.4 2.4 1.5 1 1 0 1 1 1 0 Hyaluronan mediated motility receptor C-terminal Leu_zip PF15294.6 CBZ30551.1 - 0.051 13.1 6.6 0.057 12.9 6.6 1.0 1 0 0 1 1 1 0 Leucine zipper DUF1241 PF06840.11 CBZ30551.1 - 0.053 13.2 3.4 0.071 12.8 3.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1241) CorA PF01544.18 CBZ30551.1 - 0.074 12.4 2.7 0.079 12.3 2.7 1.1 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein OmpH PF03938.14 CBZ30551.1 - 0.11 12.8 6.5 0.14 12.5 6.5 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Sec20 PF03908.13 CBZ30551.1 - 0.12 12.3 2.5 0.82 9.6 2.4 2.1 1 1 0 1 1 1 0 Sec20 Spc7 PF08317.11 CBZ30551.1 - 0.19 10.6 8.4 0.25 10.2 8.4 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein FliD_N PF02465.18 CBZ30551.1 - 0.32 11.7 6.0 0.62 10.8 5.9 1.6 1 1 0 1 1 1 0 Flagellar hook-associated protein 2 N-terminus DivIC PF04977.15 CBZ30551.1 - 0.96 9.3 10.3 0.43 10.4 0.6 2.9 1 1 2 3 3 3 0 Septum formation initiator CLZ PF16526.5 CBZ30551.1 - 1.1 9.7 7.7 2.2 8.7 2.4 2.6 1 1 2 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels DUF4140 PF13600.6 CBZ30551.1 - 2.9 8.4 7.8 4.8 7.7 3.3 2.2 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) Rcd1 PF04078.13 CBZ30552.1 - 6.9e-100 333.6 1.2 8.1e-100 333.4 1.2 1.0 1 0 0 1 1 1 1 Cell differentiation family, Rcd1-like V-ATPase_H_N PF03224.14 CBZ30552.1 - 0.13 11.6 0.1 1.2 8.3 0.0 2.3 1 1 1 2 2 2 0 V-ATPase subunit H RRM_1 PF00076.22 CBZ30553.1 - 8.2e-29 99.2 0.0 5.1e-14 51.9 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 CBZ30553.1 - 0.00027 21.0 0.0 3.3 7.8 0.0 3.3 3 0 0 3 3 3 2 RNA binding motif RRM_7 PF16367.5 CBZ30553.1 - 0.0005 20.1 0.0 0.44 10.7 0.0 3.4 3 1 0 3 3 3 2 RNA recognition motif RNA_bind PF08675.11 CBZ30553.1 - 0.014 15.4 0.1 0.73 9.9 0.0 2.7 3 1 0 3 3 3 0 RNA binding domain Nup35_RRM_2 PF14605.6 CBZ30553.1 - 0.062 13.3 0.0 0.39 10.8 0.0 2.2 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif PHM7_cyt PF14703.6 CBZ30553.1 - 0.13 12.5 2.0 8 6.7 0.2 3.0 2 2 1 3 3 3 0 Cytosolic domain of 10TM putative phosphate transporter RRM_5 PF13893.6 CBZ30553.1 - 0.18 11.4 0.0 12 5.5 0.0 2.5 2 1 1 3 3 3 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Tmemb_170 PF10190.9 CBZ30554.1 - 0.019 15.4 9.3 0.023 15.1 9.3 1.0 1 0 0 1 1 1 0 Putative transmembrane protein 170 TMEM239 PF15841.5 CBZ30554.1 - 0.32 10.9 3.8 0.38 10.6 2.1 1.8 1 1 1 2 2 2 0 Transmembrane protein 239 family TMEM40 PF15817.5 CBZ30554.1 - 2.1 8.1 6.2 0.72 9.6 1.7 2.2 1 1 2 3 3 3 0 Transmembrane protein 40 family FAM176 PF14851.6 CBZ30554.1 - 9.1 5.9 7.9 0.2 11.3 0.8 1.7 2 0 0 2 2 2 0 FAM176 family WD40 PF00400.32 CBZ30555.1 - 3e-05 24.7 4.8 0.031 15.1 0.0 4.6 5 0 0 5 5 5 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBZ30555.1 - 0.0035 17.6 0.0 8 6.8 0.0 3.9 3 1 0 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Myb_DNA-bind_6 PF13921.6 CBZ30556.1 - 0.066 13.5 0.0 2.1 8.6 0.0 2.4 1 1 1 2 2 2 0 Myb-like DNA-binding domain APS_kinase PF01583.20 CBZ30556.1 - 0.14 12.0 0.0 0.81 9.6 0.0 2.0 1 1 1 2 2 2 0 Adenylylsulphate kinase ARD PF03079.14 CBZ30557.1 - 4.1e-27 95.3 0.1 4.1e-27 95.3 0.1 2.1 2 0 0 2 2 2 1 ARD/ARD' family Cupin_2 PF07883.11 CBZ30557.1 - 1.2e-06 28.1 0.0 4.9e-06 26.2 0.0 1.9 2 0 0 2 2 2 1 Cupin domain AraC_binding PF02311.19 CBZ30557.1 - 0.00029 20.7 0.0 0.00053 19.9 0.0 1.3 1 0 0 1 1 1 1 AraC-like ligand binding domain Cupin_3 PF05899.12 CBZ30557.1 - 0.0018 18.0 0.0 0.0046 16.6 0.0 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF861) Cupin_8 PF13621.6 CBZ30557.1 - 0.029 14.1 2.2 0.047 13.4 0.0 2.1 2 1 0 2 2 2 0 Cupin-like domain Cupin_1 PF00190.22 CBZ30557.1 - 0.037 13.7 0.0 0.064 12.9 0.0 1.3 1 0 0 1 1 1 0 Cupin Cupin_6 PF12852.7 CBZ30557.1 - 0.064 13.0 0.0 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 Cupin 2OG-FeII_Oxy_5 PF13759.6 CBZ30557.1 - 0.089 13.2 0.3 0.28 11.6 0.0 2.0 2 0 0 2 2 2 0 Putative 2OG-Fe(II) oxygenase Presenilin PF01080.17 CBZ30557.1 - 0.36 9.6 2.3 0.38 9.5 2.3 1.2 1 0 0 1 1 1 0 Presenilin PhyH PF05721.13 CBZ30557.1 - 0.6 10.3 2.4 4 7.6 0.0 2.5 2 1 0 2 2 2 0 Phytanoyl-CoA dioxygenase (PhyH) AAA_17 PF13207.6 CBZ30557.1 - 0.73 10.3 8.5 23 5.4 6.5 2.2 2 0 0 2 2 2 0 AAA domain CDC45 PF02724.14 CBZ30557.1 - 1.7 6.8 10.8 2.3 6.4 10.8 1.1 1 0 0 1 1 1 0 CDC45-like protein cNMP_binding PF00027.29 CBZ30559.1 - 6.7e-09 35.7 0.0 1.6e-08 34.5 0.0 1.7 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain PK PF00224.21 CBZ30560.1 - 3.5e-90 302.4 0.2 4e-90 302.2 0.2 1.0 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain HpcH_HpaI PF03328.14 CBZ30560.1 - 0.0094 15.1 0.0 0.017 14.3 0.0 1.4 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family DUF3479 PF11965.8 CBZ30560.1 - 0.16 12.1 0.0 0.26 11.4 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3479) PK PF00224.21 CBZ30561.1 - 1.1e-136 455.3 0.3 1.7e-136 454.7 0.3 1.2 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.16 CBZ30561.1 - 6.6e-26 90.8 1.9 9.6e-26 90.3 0.3 2.2 2 0 0 2 2 2 1 Pyruvate kinase, alpha/beta domain HpcH_HpaI PF03328.14 CBZ30561.1 - 0.00098 18.3 0.7 0.0034 16.5 0.6 1.8 1 1 1 2 2 2 1 HpcH/HpaI aldolase/citrate lyase family IMPDH PF00478.25 CBZ30561.1 - 0.19 10.7 4.3 0.27 10.2 0.1 2.6 3 0 0 3 3 3 0 IMP dehydrogenase / GMP reductase domain PI-PLC-X PF00388.19 CBZ30562.1 - 4.3e-57 191.8 0.0 6.8e-57 191.1 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.19 CBZ30562.1 - 8.9e-33 113.1 0.1 2.4e-32 111.7 0.0 1.8 2 0 0 2 2 2 1 Phosphatidylinositol-specific phospholipase C, Y domain EF-hand_1 PF00036.32 CBZ30562.1 - 0.0013 18.1 0.5 0.0041 16.6 0.5 1.9 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.6 CBZ30562.1 - 0.012 16.0 0.8 0.041 14.3 0.8 1.8 1 1 1 2 2 2 0 EF-hand domain pair C2 PF00168.30 CBZ30562.1 - 0.013 15.8 0.0 0.026 14.8 0.0 1.5 1 0 0 1 1 1 0 C2 domain EF-hand_6 PF13405.6 CBZ30562.1 - 0.25 11.3 0.6 0.85 9.7 0.6 1.9 1 0 0 1 1 1 0 EF-hand domain Transket_pyr PF02779.24 CBZ30563.1 - 9.4e-41 139.4 0.0 1.6e-40 138.6 0.0 1.4 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 CBZ30563.1 - 2.2e-35 121.2 0.0 5.2e-35 120.0 0.0 1.6 2 0 0 2 2 2 1 Transketolase, C-terminal domain PFOR_II PF17147.4 CBZ30563.1 - 7.8e-06 26.1 0.0 1.4e-05 25.3 0.0 1.4 1 0 0 1 1 1 1 Pyruvate:ferredoxin oxidoreductase core domain II AAA PF00004.29 CBZ30564.1 - 0.026 14.9 0.1 0.094 13.1 0.1 2.0 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Band_7 PF01145.25 CBZ30565.1 - 1.1e-24 87.4 3.4 1.9e-24 86.6 3.4 1.4 1 1 0 1 1 1 1 SPFH domain / Band 7 family Nfu_N PF08712.11 CBZ30565.1 - 0.11 12.5 0.1 0.3 11.2 0.0 1.7 2 0 0 2 2 2 0 Scaffold protein Nfu/NifU N terminal TrkH PF02386.16 CBZ30566.1 - 3.7e-09 35.6 21.7 1.4e-08 33.7 1.9 3.5 3 1 1 4 4 4 3 Cation transport protein UCR_14kD PF02271.16 CBZ30568.1 - 1.4e-07 31.4 0.1 7.9e-07 29.0 0.0 1.9 2 0 0 2 2 2 1 Ubiquinol-cytochrome C reductase complex 14kD subunit Clat_adaptor_s PF01217.20 CBZ30569.1 - 5.2e-10 39.4 0.0 7.5e-10 38.9 0.0 1.2 1 0 0 1 1 1 1 Clathrin adaptor complex small chain OSR1_C PF12202.8 CBZ30569.1 - 0.12 12.6 0.0 0.32 11.3 0.0 1.7 1 0 0 1 1 1 0 Oxidative-stress-responsive kinase 1 C-terminal domain LMBR1 PF04791.16 CBZ30570.1 - 1.2e-17 64.0 25.9 1.4e-14 54.0 2.2 2.1 1 1 1 2 2 2 2 LMBR1-like membrane protein CTV_P33 PF07184.11 CBZ30570.1 - 0.32 10.0 0.0 0.32 10.0 0.0 2.2 3 0 0 3 3 3 0 Citrus tristeza virus P33 protein Arf PF00025.21 CBZ30571.1 - 4e-65 218.5 0.1 4.5e-65 218.4 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.20 CBZ30571.1 - 2.6e-13 49.9 1.2 8.2e-08 31.8 0.1 2.4 1 1 1 2 2 2 2 G-protein alpha subunit Roc PF08477.13 CBZ30571.1 - 3.7e-12 46.5 0.0 5.2e-12 46.1 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Gtr1_RagA PF04670.12 CBZ30571.1 - 2e-09 37.2 0.0 2.4e-09 36.9 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Ras PF00071.22 CBZ30571.1 - 1.9e-08 34.1 0.0 2.2e-08 33.9 0.0 1.1 1 0 0 1 1 1 1 Ras family SRPRB PF09439.10 CBZ30571.1 - 1.8e-07 30.8 0.0 2.3e-07 30.4 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 CBZ30571.1 - 6.4e-06 26.2 0.0 9.4e-06 25.7 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 CBZ30571.1 - 0.0041 16.7 0.1 0.016 14.7 0.1 1.9 1 1 0 1 1 1 1 Ferrous iron transport protein B TniB PF05621.11 CBZ30571.1 - 0.014 14.8 0.4 0.033 13.6 0.0 1.6 2 0 0 2 2 2 0 Bacterial TniB protein cobW PF02492.19 CBZ30571.1 - 0.017 14.7 0.1 0.092 12.3 0.0 1.9 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Mito_carr PF00153.27 CBZ30573.1 - 1.1e-05 25.2 2.0 0.064 13.2 0.3 2.9 2 1 1 3 3 3 2 Mitochondrial carrier protein DUF2157 PF09925.9 CBZ30573.1 - 5.9 6.7 9.3 0.39 10.5 2.8 2.3 2 1 0 2 2 2 0 Predicted membrane protein (DUF2157) UPF0184 PF03670.13 CBZ30575.1 - 0.16 12.4 1.5 0.47 10.9 0.1 2.3 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0184) DUF2570 PF10828.8 CBZ30575.1 - 0.21 11.4 0.1 0.21 11.4 0.1 3.3 3 1 0 3 3 3 0 Protein of unknown function (DUF2570) Exonuc_VII_L PF02601.15 CBZ30575.1 - 1.1 8.7 9.2 0.12 11.9 4.2 1.8 2 0 0 2 2 2 0 Exonuclease VII, large subunit Atg14 PF10186.9 CBZ30575.1 - 1.2 8.2 10.9 2 7.4 10.9 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DIT1_PvcA PF05141.12 CBZ30575.1 - 3.7 6.9 7.1 1.4 8.3 2.3 2.4 2 1 1 3 3 3 0 Pyoverdine/dityrosine biosynthesis protein Tropomyosin_1 PF12718.7 CBZ30575.1 - 4.7 7.4 17.9 0.029 14.5 6.1 2.8 2 1 1 3 3 3 0 Tropomyosin like BRICHOS PF04089.14 CBZ30576.1 - 0.0043 17.2 0.1 0.09 13.0 0.1 3.4 1 0 0 1 1 1 1 BRICHOS domain GAS PF13851.6 CBZ30576.1 - 0.0063 15.9 9.2 0.0063 15.9 9.2 9.3 1 1 6 9 9 9 6 Growth-arrest specific micro-tubule binding EzrA PF06160.12 CBZ30576.1 - 0.06 11.5 89.1 0.0086 14.3 19.5 5.3 2 2 1 4 4 4 0 Septation ring formation regulator, EzrA NIF PF03031.18 CBZ30577.1 - 3.2e-32 111.5 0.0 4.5e-32 111.0 0.0 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Hydrolase PF00702.26 CBZ30577.1 - 0.0002 21.7 0.0 0.00028 21.2 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 CBZ30577.1 - 0.0012 19.3 0.0 0.0053 17.2 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase DUF705 PF05152.12 CBZ30577.1 - 0.1 12.1 0.0 0.16 11.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF705) ATG16 PF08614.11 CBZ30578.1 - 0.00072 19.8 9.5 0.00072 19.8 9.5 16.6 5 4 10 16 16 16 3 Autophagy protein 16 (ATG16) DHR10 PF18595.1 CBZ30578.1 - 0.0048 16.9 4.1 0.0048 16.9 4.1 21.0 15 7 6 21 21 21 3 Designed helical repeat protein 10 domain DUF1242 PF06842.12 CBZ30579.1 - 1.4e-09 37.6 1.3 2e-09 37.1 1.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1242) DnaJ PF00226.31 CBZ30581.1 - 1.9e-05 24.7 0.0 4.9e-05 23.4 0.0 1.8 1 1 0 1 1 1 1 DnaJ domain Torus PF16131.5 CBZ30581.1 - 0.61 10.8 3.4 0.3 11.8 0.6 1.9 2 0 0 2 2 2 0 Torus domain Ribosomal_L7Ae PF01248.26 CBZ30582.1 - 2.1e-24 85.1 0.0 2.3e-24 84.9 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family ArfGap PF01412.18 CBZ30584.1 - 5.2e-29 100.7 0.1 1.2e-28 99.5 0.1 1.6 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf DUF1980 PF09323.10 CBZ30585.1 - 0.22 11.4 0.1 0.21 11.5 0.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) CCSMST1 PF15013.6 CBZ30585.1 - 0.37 11.0 1.6 3.7 7.8 0.1 2.0 1 1 1 2 2 2 0 CCSMST1 family 3HCDH PF00725.22 CBZ30587.1 - 2e-09 37.9 0.2 0.0029 18.2 0.0 2.5 2 0 0 2 2 2 2 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain Rrf2 PF02082.20 CBZ30587.1 - 0.062 13.7 0.1 0.13 12.7 0.1 1.4 1 0 0 1 1 1 0 Transcriptional regulator Nup96 PF12110.8 CBZ30588.1 - 0.026 13.7 0.0 0.055 12.6 0.0 1.6 2 0 0 2 2 2 0 Nuclear protein 96 MAD PF05557.13 CBZ30588.1 - 0.1 10.9 0.8 0.32 9.3 0.1 1.9 2 0 0 2 2 2 0 Mitotic checkpoint protein Ank_2 PF12796.7 CBZ30589.1 - 2.4e-09 37.6 0.0 2.3e-07 31.3 0.0 2.5 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 CBZ30589.1 - 5.2e-08 32.5 0.1 0.014 15.8 0.0 3.7 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.6 CBZ30589.1 - 3.2e-07 30.8 0.0 0.0041 17.7 0.0 3.1 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 CBZ30589.1 - 0.00058 20.2 0.1 0.092 13.2 0.0 3.4 3 0 0 3 3 3 1 Ankyrin repeat Ank_5 PF13857.6 CBZ30589.1 - 0.00073 19.8 0.0 0.011 16.0 0.0 2.5 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Aminotran_1_2 PF00155.21 CBZ30590.1 - 3.2e-46 158.2 0.0 3.8e-46 157.9 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 CBZ30590.1 - 0.061 12.6 0.0 4.8 6.4 0.0 2.0 2 0 0 2 2 2 0 DegT/DnrJ/EryC1/StrS aminotransferase family adh_short PF00106.25 CBZ30591.1 - 3.4e-40 137.6 0.3 4.8e-40 137.1 0.3 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CBZ30591.1 - 2.4e-24 86.2 1.1 3.2e-24 85.8 1.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CBZ30591.1 - 2.7e-15 56.7 0.8 4.4e-15 56.0 0.8 1.3 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 CBZ30591.1 - 0.00055 19.2 0.0 0.00064 18.9 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Eno-Rase_NADH_b PF12242.8 CBZ30591.1 - 0.068 12.9 0.0 0.18 11.6 0.0 1.7 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase TGBp3 PF02495.17 CBZ30591.1 - 0.094 12.4 0.5 0.2 11.3 0.5 1.5 1 0 0 1 1 1 0 Triple gene block 3 GDP_Man_Dehyd PF16363.5 CBZ30591.1 - 0.13 11.6 0.0 0.24 10.8 0.0 1.5 1 1 0 1 1 1 0 GDP-mannose 4,6 dehydratase ECH_1 PF00378.20 CBZ30594.1 - 2.4e-46 158.1 0.7 7.3e-46 156.5 0.7 1.7 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 CBZ30594.1 - 5.4e-22 78.7 0.8 8.7e-20 71.5 0.1 2.1 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase DEAD PF00270.29 CBZ30595.1 - 5.3e-45 153.3 0.4 7.7e-45 152.8 0.4 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CBZ30595.1 - 1.6e-28 99.2 1.4 7.2e-28 97.2 0.9 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ERCC3_RAD25_C PF16203.5 CBZ30595.1 - 0.00067 18.9 0.1 0.001 18.4 0.1 1.2 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase AAA_19 PF13245.6 CBZ30595.1 - 0.0057 17.0 0.3 0.01 16.2 0.3 1.4 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 CBZ30595.1 - 0.0059 16.9 0.3 0.018 15.3 0.3 1.8 1 1 0 1 1 1 1 AAA domain AAA PF00004.29 CBZ30595.1 - 0.11 12.9 0.8 1.9 8.9 0.8 2.6 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Thioredoxin PF00085.20 CBZ30596.1 - 6.2e-05 22.9 0.0 0.00013 21.9 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 CBZ30596.1 - 0.00013 22.2 0.1 0.026 14.8 0.0 2.4 1 1 1 2 2 2 2 Thioredoxin-like Thioredoxin_9 PF14595.6 CBZ30596.1 - 0.15 11.8 0.0 0.31 10.8 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin Thioredoxin_2 PF13098.6 CBZ30596.1 - 0.16 12.5 0.0 0.85 10.1 0.0 2.1 1 1 0 1 1 1 0 Thioredoxin-like domain Ribosomal_S3Ae PF01015.18 CBZ30598.1 - 3.3e-68 229.3 3.9 4e-68 229.0 3.9 1.0 1 0 0 1 1 1 1 Ribosomal S3Ae family DNA_pol3_delt_C PF14840.6 CBZ30598.1 - 0.076 13.3 2.4 0.12 12.7 2.0 1.5 1 1 0 1 1 1 0 Processivity clamp loader gamma complex DNA pol III C-term SHIPPO-rpt PF07004.12 CBZ30599.1 - 3.9e-13 49.6 23.0 0.19 12.7 0.0 9.5 9 0 0 9 9 9 7 Sperm-tail PG-rich repeat Arrestin_N PF00339.29 CBZ30600.1 - 5.2e-09 36.3 0.0 1.8e-08 34.5 0.0 1.9 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain Arrestin_N PF00339.29 CBZ30601.1 - 8.7e-05 22.6 0.0 0.00022 21.3 0.0 1.6 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain dsrm PF00035.26 CBZ30601.1 - 2 9.2 4.4 2.6 8.8 0.0 2.8 3 0 0 3 3 3 0 Double-stranded RNA binding motif HAP2-GCS1 PF10699.9 CBZ30602.1 - 5.6e-20 71.0 0.1 2.5e-19 69.0 0.0 2.1 2 0 0 2 2 2 1 Male gamete fusion factor DUF3737 PF12541.8 CBZ30602.1 - 0.13 11.4 0.0 6.3 5.9 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3737) Pkinase PF00069.25 CBZ30605.1 - 5.1e-51 173.6 0.0 1.3e-31 109.9 0.0 3.3 3 0 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ30605.1 - 8e-25 87.6 0.1 7.6e-19 68.0 0.1 3.1 3 0 0 3 3 3 2 Protein tyrosine kinase EF-hand_7 PF13499.6 CBZ30605.1 - 8.3e-08 32.6 0.3 0.0027 18.1 0.0 2.6 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 CBZ30605.1 - 1.5e-07 30.8 0.0 0.0061 16.4 0.0 2.7 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.32 CBZ30605.1 - 0.00019 20.7 0.0 0.12 12.0 0.0 3.1 3 0 0 3 3 3 2 EF hand Kinase-like PF14531.6 CBZ30605.1 - 0.00034 20.0 0.0 0.27 10.5 0.0 2.2 2 0 0 2 2 2 2 Kinase-like Kdo PF06293.14 CBZ30605.1 - 0.15 11.4 0.0 0.3 10.4 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family LRR_8 PF13855.6 CBZ30606.1 - 4.9e-15 55.0 21.2 7.3e-08 32.1 1.9 5.0 4 1 2 6 6 6 5 Leucine rich repeat LRR_4 PF12799.7 CBZ30606.1 - 8.8e-09 35.5 25.8 0.00055 20.3 1.6 6.6 4 2 5 9 9 9 6 Leucine Rich repeats (2 copies) DUF3079 PF11278.8 CBZ30606.1 - 0.56 10.1 3.3 2.5 8.0 0.4 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3079) LRR_1 PF00560.33 CBZ30606.1 - 0.6 10.9 11.3 1.3e+02 3.8 0.4 7.1 8 0 0 8 8 8 0 Leucine Rich Repeat LRR_4 PF12799.7 CBZ30607.1 - 5.6e-10 39.3 6.9 0.0019 18.6 1.7 5.4 4 1 4 8 8 8 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CBZ30607.1 - 1.5e-09 37.5 10.8 2.6e-07 30.3 3.2 4.3 3 1 2 5 5 5 3 Leucine rich repeat LRR_1 PF00560.33 CBZ30607.1 - 1.1 10.1 3.1 1.8e+02 3.3 0.0 5.7 6 0 0 6 6 6 0 Leucine Rich Repeat PIP5K PF01504.18 CBZ30608.1 - 8.4e-59 199.0 0.0 2.5e-58 197.5 0.0 1.8 1 1 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase DUF4763 PF15960.5 CBZ30608.1 - 0.99 8.7 8.8 0.11 11.8 1.9 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4763) CAP_N PF01213.19 CBZ30608.1 - 1.7 8.0 6.6 5 6.5 6.6 1.7 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal WD40 PF00400.32 CBZ30609.1 - 2.8e-05 24.8 20.9 0.0019 19.0 1.3 6.3 7 0 0 7 7 7 3 WD domain, G-beta repeat Snf7 PF03357.21 CBZ30610.1 - 2.9e-38 131.2 18.5 3.4e-38 130.9 18.5 1.0 1 0 0 1 1 1 1 Snf7 NPV_P10 PF05531.12 CBZ30610.1 - 0.02 15.3 1.6 0.02 15.3 1.6 2.6 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein XRN_M PF17846.1 CBZ30610.1 - 0.14 11.1 6.2 0.19 10.6 6.2 1.2 1 0 0 1 1 1 0 Xrn1 helical domain DUF3573 PF12097.8 CBZ30610.1 - 0.42 9.4 2.6 0.55 9.0 2.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) FlaC_arch PF05377.11 CBZ30610.1 - 0.42 11.0 2.7 17 5.9 0.3 3.0 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) DUF2890 PF11081.8 CBZ30610.1 - 8.8 6.4 7.9 0.85 9.7 0.5 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF2890) HTH_17 PF12728.7 CBZ30611.1 - 0.24 11.6 1.1 8.2 6.7 0.1 2.5 2 0 0 2 2 2 0 Helix-turn-helix domain Ribosomal_L18A PF01775.17 CBZ30612.1 - 4.3e-41 139.8 1.1 5.7e-41 139.4 1.1 1.2 1 0 0 1 1 1 1 Ribosomal proteins 50S-L18Ae/60S-L20/60S-L18A Nup35_RRM_2 PF14605.6 CBZ30615.1 - 9.5e-15 54.3 0.0 1.5e-14 53.7 0.0 1.3 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif Glyco_hydro_32N PF00251.20 CBZ30616.1 - 1.3e-56 192.4 4.9 5.1e-55 187.2 4.1 2.3 2 0 0 2 2 2 2 Glycosyl hydrolases family 32 N-terminal domain Glyco_hydro_32C PF08244.12 CBZ30616.1 - 7.3e-16 58.6 0.0 3.6e-15 56.3 0.0 2.0 1 1 0 1 1 1 1 Glycosyl hydrolases family 32 C terminal PAN_4 PF14295.6 CBZ30616.1 - 0.00032 20.6 1.7 0.0011 18.8 1.7 1.9 1 0 0 1 1 1 1 PAN domain zf-C3HC4_2 PF13923.6 CBZ30617.1 - 0.0056 16.5 6.9 0.0056 16.5 6.9 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CBZ30617.1 - 0.01 16.1 12.6 0.012 16.0 9.1 2.5 2 0 0 2 2 2 0 Ring finger domain zf-RING_UBOX PF13445.6 CBZ30617.1 - 0.088 12.8 9.6 0.019 15.0 5.7 1.9 2 0 0 2 2 2 0 RING-type zinc-finger zf-RING_6 PF14835.6 CBZ30617.1 - 0.089 12.7 9.3 0.013 15.4 4.7 1.9 2 0 0 2 2 2 0 zf-RING of BARD1-type protein zf-C3HC4 PF00097.25 CBZ30617.1 - 0.62 10.0 14.0 0.083 12.8 8.9 2.1 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CBZ30617.1 - 1.1 9.2 13.3 0.12 12.4 8.2 2.0 2 0 0 2 2 2 0 zinc-RING finger domain zf-C3HC4_3 PF13920.6 CBZ30617.1 - 2 8.4 12.5 0.85 9.5 7.4 2.4 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 CBZ30617.1 - 2.6 8.0 14.6 0.32 10.9 8.0 2.7 3 0 0 3 3 3 0 Prokaryotic RING finger family 4 DUF1272 PF06906.11 CBZ30617.1 - 5 7.3 9.8 0.79 9.9 5.5 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1272) DRIM PF07539.12 CBZ30618.1 - 1.8e-12 46.4 0.0 1.8e-12 46.4 0.0 6.1 7 0 0 7 7 7 3 Down-regulated in metastasis TPR_12 PF13424.6 CBZ30620.1 - 2e-60 201.0 39.3 2.1e-13 50.4 1.2 8.2 6 2 2 8 8 8 8 Tetratricopeptide repeat TPR_10 PF13374.6 CBZ30620.1 - 3e-43 144.6 26.7 3.7e-06 26.6 0.1 11.9 12 0 0 12 12 12 10 Tetratricopeptide repeat TPR_2 PF07719.17 CBZ30620.1 - 4.5e-22 76.3 41.0 0.0043 17.1 0.1 12.4 12 1 0 12 12 12 6 Tetratricopeptide repeat TPR_8 PF13181.6 CBZ30620.1 - 3.8e-20 70.4 37.8 0.044 14.0 0.0 12.6 14 0 0 14 14 14 7 Tetratricopeptide repeat TPR_1 PF00515.28 CBZ30620.1 - 2.7e-19 68.1 44.0 5.1e-05 22.9 0.0 12.5 14 0 0 14 14 14 6 Tetratricopeptide repeat TPR_7 PF13176.6 CBZ30620.1 - 2.3e-15 55.4 23.2 0.001 18.9 0.1 9.9 11 1 0 11 11 11 4 Tetratricopeptide repeat TPR_16 PF13432.6 CBZ30620.1 - 5.2e-13 49.4 24.4 0.0038 17.8 0.1 8.0 6 2 2 8 8 8 3 Tetratricopeptide repeat TPR_MalT PF17874.1 CBZ30620.1 - 7.1e-09 35.5 14.4 0.00067 19.1 5.1 4.3 2 1 2 5 5 5 4 MalT-like TPR region TPR_14 PF13428.6 CBZ30620.1 - 1.4e-08 34.8 31.7 3.7 8.6 0.1 11.0 10 2 2 12 12 11 2 Tetratricopeptide repeat TPR_19 PF14559.6 CBZ30620.1 - 9e-07 29.3 23.5 0.02 15.4 0.7 7.4 8 0 0 8 8 8 2 Tetratricopeptide repeat ANAPC5 PF12862.7 CBZ30620.1 - 0.025 14.7 14.6 3.3 7.8 0.4 6.1 4 2 1 5 5 5 0 Anaphase-promoting complex subunit 5 SET_assoc PF11767.8 CBZ30620.1 - 0.027 14.1 0.0 0.081 12.6 0.0 1.8 1 0 0 1 1 1 0 Histone lysine methyltransferase SET associated SHNi-TPR PF10516.9 CBZ30620.1 - 0.028 13.9 2.1 37 3.9 0.0 4.4 5 0 0 5 5 5 0 SHNi-TPR DUF3856 PF12968.7 CBZ30620.1 - 0.28 11.3 3.2 4.2 7.4 1.2 3.4 2 2 1 3 3 3 0 Domain of Unknown Function (DUF3856) TPR_17 PF13431.6 CBZ30620.1 - 1 9.9 18.9 16 6.2 0.1 7.4 8 1 0 8 8 7 0 Tetratricopeptide repeat ANAPC3 PF12895.7 CBZ30620.1 - 2 8.7 36.3 0.37 11.0 3.3 7.5 4 4 4 8 8 8 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_11 PF13414.6 CBZ30620.1 - 3.2 7.5 12.0 26 4.6 0.0 5.8 6 1 0 6 6 6 0 TPR repeat MIT PF04212.18 CBZ30620.1 - 4.1 7.5 12.4 16 5.7 0.1 5.4 6 0 0 6 6 6 0 MIT (microtubule interacting and transport) domain ATP-synt_D PF01813.17 CBZ30621.1 - 4e-74 248.7 0.5 5.6e-74 248.2 0.5 1.2 1 0 0 1 1 1 1 ATP synthase subunit D Receptor_IA-2 PF11548.8 CBZ30621.1 - 0.11 12.5 1.6 1.6 8.8 0.1 2.7 3 0 0 3 3 3 0 Protein-tyrosine phosphatase receptor IA-2 Exo_endo_phos PF03372.23 CBZ30622.1 - 1e-06 28.4 0.0 3.6e-06 26.7 0.0 2.0 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family SET PF00856.28 CBZ30624.1 - 5.3e-12 46.4 0.2 5e-08 33.5 0.0 3.0 1 1 1 2 2 2 2 SET domain DUF1502 PF07397.11 CBZ30624.1 - 4.2 7.3 10.1 0.79 9.6 5.5 2.2 2 0 0 2 2 2 0 Repeat of unknown function (DUF1502) FHA PF00498.26 CBZ30625.1 - 0.001 19.4 0.0 0.0032 17.8 0.0 2.0 1 1 0 1 1 1 1 FHA domain PA28_beta PF02252.18 CBZ30626.1 - 5.7e-10 39.0 0.1 1.5e-05 24.7 0.0 2.3 2 0 0 2 2 2 2 Proteasome activator pa28 beta subunit CBS PF00571.28 CBZ30627.1 - 3e-16 59.6 1.0 0.00013 22.3 0.0 4.3 4 0 0 4 4 4 4 CBS domain RrnaAD PF00398.20 CBZ30628.1 - 6e-26 91.1 0.0 9e-16 57.7 0.0 2.1 2 0 0 2 2 2 2 Ribosomal RNA adenine dimethylase Methyltransf_12 PF08242.12 CBZ30628.1 - 0.00065 20.4 0.0 0.0016 19.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain DOT1 PF08123.13 CBZ30628.1 - 0.2 11.2 0.0 0.32 10.5 0.0 1.3 1 0 0 1 1 1 0 Histone methylation protein DOT1 SlyX PF04102.12 CBZ30629.1 - 0.019 15.5 2.6 0.019 15.5 2.6 4.6 5 1 1 6 6 6 0 SlyX Actin PF00022.19 CBZ30630.1 - 6.1e-59 199.6 0.0 1.7e-47 162.0 0.0 2.0 2 0 0 2 2 2 2 Actin ZapB PF06005.12 CBZ30631.1 - 0.84 10.1 4.9 2.9 8.4 0.1 3.0 3 0 0 3 3 3 0 Cell division protein ZapB Aminotran_1_2 PF00155.21 CBZ30633.1 - 8.4e-68 229.2 0.0 9.6e-68 229.0 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II FYVE_2 PF02318.16 CBZ30633.1 - 0.028 14.6 0.0 0.055 13.7 0.0 1.4 1 0 0 1 1 1 0 FYVE-type zinc finger FAD_binding_2 PF00890.24 CBZ30634.1 - 1.2e-81 274.9 0.0 1.8e-81 274.4 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain ApbE PF02424.15 CBZ30634.1 - 6.7e-50 170.0 0.0 2.3e-49 168.3 0.0 1.9 1 1 0 1 1 1 1 ApbE family NAD_binding_1 PF00175.21 CBZ30634.1 - 2.8e-18 66.5 0.0 5.6e-18 65.6 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain DAO PF01266.24 CBZ30634.1 - 6.3e-13 49.0 0.2 1.2e-12 48.1 0.2 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_oxidored PF12831.7 CBZ30634.1 - 1.5e-09 37.8 3.4 2.9e-09 36.8 3.4 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_6 PF00970.24 CBZ30634.1 - 4.5e-09 36.6 0.0 1.1e-08 35.4 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain Pyr_redox_2 PF07992.14 CBZ30634.1 - 1.1e-07 31.4 0.0 3.3e-07 29.8 0.0 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 CBZ30634.1 - 5.9e-07 29.6 0.7 2.8e-06 27.5 0.7 2.2 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain AlaDh_PNT_C PF01262.21 CBZ30634.1 - 1e-06 28.2 0.3 2.5e-06 27.0 0.3 1.6 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain GIDA PF01134.22 CBZ30634.1 - 8.7e-06 25.1 4.8 4.9e-05 22.6 2.7 2.4 2 0 0 2 2 2 1 Glucose inhibited division protein A HI0933_like PF03486.14 CBZ30634.1 - 0.00052 18.8 4.0 0.0011 17.7 2.1 2.3 3 0 0 3 3 3 1 HI0933-like protein NAD_binding_6 PF08030.12 CBZ30634.1 - 0.002 18.3 0.0 0.03 14.4 0.0 2.4 2 0 0 2 2 2 1 Ferric reductase NAD binding domain Pyr_redox PF00070.27 CBZ30634.1 - 0.0043 17.6 0.7 0.011 16.2 0.7 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 CBZ30634.1 - 0.01 15.2 0.5 0.075 12.3 0.3 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 CBZ30634.1 - 0.37 9.8 2.2 0.36 9.8 0.9 1.6 2 0 0 2 2 2 0 Lycopene cyclase protein DUF2838 PF10998.8 CBZ30636.1 - 6.6e-15 55.3 23.3 6.7e-10 39.2 5.5 3.6 3 0 0 3 3 3 2 Protein of unknown function (DUF2838) Telomere_reg-2 PF10193.9 CBZ30638.1 - 0.0023 18.3 0.0 0.021 15.3 0.0 2.5 2 0 0 2 2 2 1 Telomere length regulation protein COX6B PF02297.17 CBZ30640.1 - 0.013 15.7 0.1 0.27 11.5 0.0 2.3 2 0 0 2 2 2 0 Cytochrome oxidase c subunit VIb UPF0203 PF05254.12 CBZ30640.1 - 0.014 15.7 0.1 0.15 12.3 0.1 2.1 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0203) GP120 PF00516.18 CBZ30640.1 - 0.019 13.6 0.0 0.023 13.3 0.0 1.2 1 0 0 1 1 1 0 Envelope glycoprotein GP120 CX9C PF16860.5 CBZ30640.1 - 0.13 12.3 1.9 0.32 11.0 0.2 2.1 2 0 0 2 2 2 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, UPF0444 PF15475.6 CBZ30643.1 - 0.075 13.3 0.2 0.075 13.3 0.2 2.1 2 0 0 2 2 2 0 Transmembrane protein C12orf23, UPF0444 HemY_N PF07219.13 CBZ30643.1 - 0.29 11.4 2.0 2.2 8.5 2.0 2.6 1 0 0 1 1 1 0 HemY protein N-terminus HTH_24 PF13412.6 CBZ30644.1 - 0.069 12.7 0.1 8.4 6.1 0.0 2.4 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding DUF2207 PF09972.9 CBZ30644.1 - 0.11 11.2 0.0 0.12 11.2 0.0 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Mrpl_C PF18502.1 CBZ30644.1 - 0.13 12.5 1.2 0.17 12.2 1.2 1.2 1 0 0 1 1 1 0 54S ribosomal protein L8 C-terminal domain PSP1 PF04468.12 CBZ30646.1 - 3.3e-23 81.8 0.3 8.7e-23 80.4 0.3 1.8 1 0 0 1 1 1 1 PSP1 C-terminal conserved region Cupin_8 PF13621.6 CBZ30647.1 - 0.11 12.2 0.0 0.23 11.1 0.0 1.5 1 0 0 1 1 1 0 Cupin-like domain Aldose_epim PF01263.20 CBZ30648.1 - 6.2e-40 137.4 0.0 7.4e-40 137.1 0.0 1.0 1 0 0 1 1 1 1 Aldose 1-epimerase DUF362 PF04015.12 CBZ30648.1 - 0.009 16.3 0.0 0.018 15.3 0.0 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF362) Aldose_epim PF01263.20 CBZ30649.1 - 2.1e-47 161.9 0.0 2.4e-47 161.7 0.0 1.0 1 0 0 1 1 1 1 Aldose 1-epimerase SRP-alpha_N PF04086.13 CBZ30650.1 - 6.1 6.7 11.1 19 5.1 11.1 1.9 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Pkinase PF00069.25 CBZ30651.1 - 2.8e-24 85.9 0.0 3.4e-24 85.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 CBZ30651.1 - 1.1e-10 40.9 0.1 1.4e-10 40.5 0.1 1.1 1 0 0 1 1 1 1 Fungal protein kinase Pkinase_Tyr PF07714.17 CBZ30651.1 - 1.2e-10 41.1 0.0 1.4e-10 40.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 CBZ30651.1 - 7.6e-07 29.3 0.0 0.00045 20.2 0.0 2.5 2 1 1 3 3 3 2 Phosphotransferase enzyme family Kdo PF06293.14 CBZ30651.1 - 0.0071 15.7 0.3 0.012 15.0 0.3 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family polyprenyl_synt PF00348.17 CBZ30651.1 - 0.14 11.2 0.0 0.24 10.4 0.0 1.3 1 0 0 1 1 1 0 Polyprenyl synthetase Pkinase PF00069.25 CBZ30652.1 - 1.3e-24 87.0 0.0 1.9e-24 86.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ30652.1 - 4.5e-13 49.1 0.0 5.7e-13 48.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CBZ30652.1 - 9.9e-09 34.4 0.0 1.3e-08 34.0 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 CBZ30652.1 - 9.9e-05 22.4 0.0 0.00024 21.1 0.0 1.7 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 CBZ30652.1 - 0.0081 15.5 0.0 0.014 14.8 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family zf-CCCH PF00642.24 CBZ30653.1 - 8.2e-06 25.6 6.4 1.3e-05 24.9 6.4 1.3 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Cupin_5 PF06172.11 CBZ30654.1 - 9.2e-43 145.8 0.0 1.2e-42 145.4 0.0 1.1 1 0 0 1 1 1 1 Cupin superfamily (DUF985) zf-CCCH PF00642.24 CBZ30655.1 - 5.3e-07 29.4 1.0 1.1e-06 28.4 1.0 1.5 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 CBZ30655.1 - 0.00035 20.5 0.8 0.00071 19.5 0.8 1.6 1 0 0 1 1 1 1 Zinc finger domain zf-CCCH_2 PF14608.6 CBZ30655.1 - 0.022 15.3 0.6 0.044 14.3 0.6 1.6 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger zf-CCCH_4 PF18044.1 CBZ30655.1 - 0.072 12.9 1.2 0.17 11.8 1.2 1.7 1 0 0 1 1 1 0 CCCH-type zinc finger Presenilin PF01080.17 CBZ30655.1 - 1.1 7.9 5.2 1.6 7.4 5.2 1.2 1 0 0 1 1 1 0 Presenilin Membralin PF09746.9 CBZ30655.1 - 1.5 7.8 5.9 2.3 7.2 5.9 1.2 1 0 0 1 1 1 0 Tumour-associated protein Pkinase PF00069.25 CBZ30656.1 - 1.6e-62 211.3 0.0 4.4e-62 209.8 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ30656.1 - 2.4e-22 79.5 0.1 1.1e-21 77.3 0.1 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CBZ30656.1 - 6.5e-05 22.4 0.1 0.049 12.9 0.2 2.9 2 1 1 3 3 3 2 Kinase-like Kdo PF06293.14 CBZ30656.1 - 0.0023 17.3 0.1 0.004 16.5 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 CBZ30656.1 - 0.017 13.9 0.2 0.05 12.4 0.0 1.8 2 0 0 2 2 2 0 Fungal protein kinase LCE PF14672.6 CBZ30656.1 - 0.045 14.3 1.9 0.096 13.3 1.9 1.4 1 0 0 1 1 1 0 Late cornified envelope FTA2 PF13095.6 CBZ30656.1 - 0.048 13.3 0.2 0.39 10.3 0.1 2.4 2 1 1 3 3 3 0 Kinetochore Sim4 complex subunit FTA2 DUF1645 PF07816.11 CBZ30656.1 - 0.11 13.1 5.1 0.025 15.1 1.8 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1645) YL1 PF05764.13 CBZ30658.1 - 0.0022 18.1 2.2 0.0035 17.5 2.2 1.2 1 0 0 1 1 1 1 YL1 nuclear protein CDC45 PF02724.14 CBZ30658.1 - 0.0077 14.6 2.3 0.011 14.1 2.3 1.1 1 0 0 1 1 1 1 CDC45-like protein Nop53 PF07767.11 CBZ30658.1 - 0.041 13.3 1.6 0.069 12.5 1.6 1.2 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) eIF3_subunit PF08597.10 CBZ30658.1 - 0.075 12.9 1.5 0.12 12.3 1.5 1.2 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit Rrn6 PF10214.9 CBZ30658.1 - 0.42 9.1 4.2 0.61 8.5 4.2 1.1 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor BUD22 PF09073.10 CBZ30658.1 - 1.4 8.2 7.0 0.87 8.9 1.3 2.0 2 0 0 2 2 2 0 BUD22 CENP-B_dimeris PF09026.10 CBZ30658.1 - 1.5 9.3 7.3 3.5 8.1 7.3 1.6 1 0 0 1 1 1 0 Centromere protein B dimerisation domain NOA36 PF06524.12 CBZ30658.1 - 4.4 6.6 5.6 8.4 5.6 5.6 1.3 1 0 0 1 1 1 0 NOA36 protein Kri1 PF05178.12 CBZ30659.1 - 2.3e-19 69.8 9.9 2.3e-19 69.8 9.9 4.0 4 0 0 4 4 4 1 KRI1-like family Kri1_C PF12936.7 CBZ30659.1 - 3.4e-18 65.6 0.0 3.4e-18 65.6 0.0 2.3 2 0 0 2 2 2 1 KRI1-like family C-terminal Peptidase_M15_3 PF08291.11 CBZ30660.1 - 0.064 13.3 0.1 0.15 12.1 0.1 1.6 1 0 0 1 1 1 0 Peptidase M15 Rdx PF10262.9 CBZ30661.1 - 0.00037 20.6 0.0 0.00076 19.6 0.0 1.5 1 0 0 1 1 1 1 Rdx family Pterin_4a PF01329.19 CBZ30661.1 - 0.37 11.0 5.0 0.55 10.4 1.4 2.3 1 1 1 2 2 2 0 Pterin 4 alpha carbinolamine dehydratase TraG-D_C PF12696.7 CBZ30662.1 - 0.13 12.3 2.2 0.21 11.6 2.2 1.4 1 0 0 1 1 1 0 TraM recognition site of TraD and TraG Hamartin PF04388.12 CBZ30662.1 - 0.23 10.1 5.4 0.26 9.9 5.4 1.0 1 0 0 1 1 1 0 Hamartin protein CECR6_TMEM121 PF14997.6 CBZ30662.1 - 0.24 11.2 0.0 0.39 10.5 0.0 1.3 1 0 0 1 1 1 0 CECR6/TMEM121 family DDHD PF02862.17 CBZ30662.1 - 0.56 10.3 4.3 0.69 10.0 4.3 1.2 1 0 0 1 1 1 0 DDHD domain Hydin_ADK PF17213.3 CBZ30662.1 - 1.9 8.7 9.0 2.5 8.3 9.0 1.1 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain STT3 PF02516.14 CBZ30663.1 - 3.2e-45 155.0 28.8 2.8e-42 145.3 27.0 2.1 2 0 0 2 2 2 2 Oligosaccharyl transferase STT3 subunit PMT PF02366.18 CBZ30663.1 - 5e-06 26.3 11.4 1.5e-05 24.7 11.4 1.8 1 0 0 1 1 1 1 Dolichyl-phosphate-mannose-protein mannosyltransferase Wzy_C PF04932.15 CBZ30663.1 - 2.4 7.8 8.8 3.1 7.4 1.1 3.5 4 0 0 4 4 4 0 O-Antigen ligase STT3 PF02516.14 CBZ30664.1 - 1.3e-45 156.3 25.3 2e-42 145.8 23.1 2.1 2 0 0 2 2 2 2 Oligosaccharyl transferase STT3 subunit PMT PF02366.18 CBZ30664.1 - 0.0011 18.6 11.0 0.0011 18.6 11.0 2.4 2 0 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase Mannosyl_trans4 PF15971.5 CBZ30664.1 - 1.8 8.4 14.3 0.31 10.9 7.5 2.5 2 0 0 2 2 2 0 DolP-mannose mannosyltransferase CEND1 PF15677.5 CBZ30664.1 - 4.6 7.8 6.7 0.74 10.3 0.1 2.6 3 0 0 3 3 3 0 Cell cycle exit and neuronal differentiation protein 1 STT3 PF02516.14 CBZ30665.1 - 1.7e-45 155.9 29.1 3.1e-45 155.0 29.1 1.4 1 1 0 1 1 1 1 Oligosaccharyl transferase STT3 subunit Mannosyl_trans4 PF15971.5 CBZ30665.1 - 1.6 8.5 17.0 0.087 12.7 6.7 3.1 2 1 0 2 2 2 0 DolP-mannose mannosyltransferase STT3 PF02516.14 CBZ30666.1 - 4.5e-46 157.8 18.9 8.4e-44 150.3 14.5 2.1 1 1 1 2 2 2 2 Oligosaccharyl transferase STT3 subunit Mannosyl_trans4 PF15971.5 CBZ30666.1 - 0.62 9.9 15.1 0.27 11.1 7.2 2.6 2 0 0 2 2 2 0 DolP-mannose mannosyltransferase Rhodanese PF00581.20 CBZ30667.1 - 2.6e-08 34.4 0.0 6.8e-08 33.0 0.0 1.7 1 0 0 1 1 1 1 Rhodanese-like domain FAD_binding_2 PF00890.24 CBZ30668.1 - 1.5e-84 284.5 0.1 2.2e-84 284.0 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain ApbE PF02424.15 CBZ30668.1 - 3.7e-55 187.2 0.0 5.9e-55 186.6 0.0 1.2 1 0 0 1 1 1 1 ApbE family NAD_binding_1 PF00175.21 CBZ30668.1 - 2.1e-18 67.0 0.0 6.4e-18 65.4 0.0 1.9 2 0 0 2 2 1 1 Oxidoreductase NAD-binding domain DAO PF01266.24 CBZ30668.1 - 7.8e-11 42.1 3.2 7.8e-10 38.9 3.1 2.2 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_oxidored PF12831.7 CBZ30668.1 - 4.9e-10 39.3 3.3 1.2e-09 38.0 3.3 1.7 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 CBZ30668.1 - 1.3e-08 34.5 0.4 5.5e-08 32.4 0.3 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 CBZ30668.1 - 6.3e-08 32.7 1.0 5.5e-07 29.7 0.8 2.7 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_6 PF00970.24 CBZ30668.1 - 1.5e-07 31.7 0.0 3.2e-07 30.6 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain GIDA PF01134.22 CBZ30668.1 - 4.8e-07 29.2 5.4 4.4e-06 26.0 2.8 2.4 2 0 0 2 2 2 1 Glucose inhibited division protein A NAD_binding_6 PF08030.12 CBZ30668.1 - 1.8e-06 28.2 0.0 0.002 18.3 0.0 2.5 2 0 0 2 2 2 2 Ferric reductase NAD binding domain AlaDh_PNT_C PF01262.21 CBZ30668.1 - 3.3e-06 26.6 0.7 7.6e-06 25.4 0.7 1.5 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain HI0933_like PF03486.14 CBZ30668.1 - 1.6e-05 23.8 3.6 0.00017 20.4 1.6 2.5 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox PF00070.27 CBZ30668.1 - 0.00015 22.3 1.7 0.0004 20.9 0.2 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 CBZ30668.1 - 0.0002 20.7 0.4 0.026 13.8 0.3 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 CBZ30668.1 - 0.0043 16.4 0.4 0.0072 15.6 0.4 1.3 1 0 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.12 CBZ30668.1 - 0.0067 15.5 2.4 0.023 13.8 1.0 2.1 2 0 0 2 2 2 1 Lycopene cyclase protein Thi4 PF01946.17 CBZ30668.1 - 4.1 6.6 7.3 0.19 10.9 0.4 2.4 3 0 0 3 3 3 0 Thi4 family FAD_binding_2 PF00890.24 CBZ30669.1 - 2.8e-89 300.1 0.6 3.2e-89 299.9 0.6 1.0 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 CBZ30669.1 - 2e-10 40.8 3.0 9.3e-08 32.0 1.4 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 CBZ30669.1 - 4.7e-09 35.9 0.5 1.1e-08 34.7 0.4 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 CBZ30669.1 - 3.4e-08 33.3 3.1 5.9e-08 32.5 3.1 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 CBZ30669.1 - 6.5e-08 32.7 0.7 2.2e-07 31.0 0.7 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.22 CBZ30669.1 - 0.00023 20.4 10.2 0.00045 19.4 2.7 2.9 3 0 0 3 3 3 1 Glucose inhibited division protein A Pyr_redox_3 PF13738.6 CBZ30669.1 - 0.00081 18.7 2.3 0.13 11.5 1.3 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 CBZ30669.1 - 0.0012 17.7 8.1 0.0056 15.4 1.2 3.1 3 0 0 3 3 3 2 HI0933-like protein FAD_binding_3 PF01494.19 CBZ30669.1 - 0.012 14.9 1.7 0.017 14.4 1.7 1.4 1 1 0 1 1 1 0 FAD binding domain AlaDh_PNT_C PF01262.21 CBZ30669.1 - 0.032 13.5 0.7 0.058 12.7 0.7 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Thi4 PF01946.17 CBZ30669.1 - 0.092 12.0 3.4 0.041 13.1 0.8 1.7 2 0 0 2 2 2 0 Thi4 family Pyr_redox PF00070.27 CBZ30669.1 - 0.16 12.6 2.4 0.13 12.9 0.6 1.8 2 0 0 2 2 1 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 CBZ30669.1 - 0.19 10.8 1.1 2.2 7.2 0.6 2.0 2 0 0 2 2 2 0 Lycopene cyclase protein NAD_binding_9 PF13454.6 CBZ30669.1 - 0.31 11.0 1.1 8.3 6.4 0.0 2.3 2 0 0 2 2 2 0 FAD-NAD(P)-binding MCRA PF06100.11 CBZ30669.1 - 0.73 8.6 1.4 8.1 5.1 0.9 2.0 2 0 0 2 2 2 0 MCRA family HA2 PF04408.23 CBZ30670.1 - 1.8e-19 70.0 0.0 4.4e-19 68.8 0.0 1.7 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.31 CBZ30670.1 - 2.8e-15 56.6 0.0 7.8e-15 55.2 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain OB_NTP_bind PF07717.16 CBZ30670.1 - 7.5e-14 51.9 0.1 1.7e-13 50.7 0.1 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold DEAD PF00270.29 CBZ30670.1 - 9.5e-08 32.0 0.1 2.8e-07 30.5 0.1 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_22 PF13401.6 CBZ30670.1 - 3e-07 30.8 0.0 8.2e-07 29.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 CBZ30670.1 - 0.00022 21.6 0.0 0.00045 20.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_7 PF12775.7 CBZ30670.1 - 0.00046 19.7 0.0 0.0016 18.0 0.0 1.9 1 0 0 1 1 1 1 P-loop containing dynein motor region ResIII PF04851.15 CBZ30670.1 - 0.0019 18.2 0.0 0.052 13.6 0.0 2.3 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit T2SSE PF00437.20 CBZ30670.1 - 0.0025 16.9 0.0 0.005 15.9 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_30 PF13604.6 CBZ30670.1 - 0.0039 16.9 0.0 0.0068 16.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.27 CBZ30670.1 - 0.0065 17.0 0.1 0.13 12.7 0.1 2.4 1 1 0 1 1 1 1 ABC transporter AAA_24 PF13479.6 CBZ30670.1 - 0.013 15.3 0.0 0.026 14.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain SRP54 PF00448.22 CBZ30670.1 - 0.027 14.1 0.0 0.068 12.8 0.0 1.7 2 1 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_16 PF13191.6 CBZ30670.1 - 0.083 13.3 0.1 0.35 11.2 0.1 2.0 1 1 0 1 1 1 0 AAA ATPase domain Sigma54_activat PF00158.26 CBZ30670.1 - 0.14 11.8 0.0 1.1 8.9 0.0 2.1 2 0 0 2 2 2 0 Sigma-54 interaction domain Armet PF10208.9 CBZ30671.1 - 1.7e-08 34.5 0.0 4.2e-08 33.3 0.0 1.6 1 0 0 1 1 1 1 Degradation arginine-rich protein for mis-folding SAP PF02037.27 CBZ30671.1 - 0.00016 21.3 0.2 0.00039 20.1 0.0 1.7 2 0 0 2 2 2 1 SAP domain DUF4554 PF15091.6 CBZ30671.1 - 0.22 10.4 0.2 6.1 5.6 0.0 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4554) adh_short PF00106.25 CBZ30672.1 - 5.6e-47 159.7 0.8 6.6e-47 159.5 0.8 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CBZ30672.1 - 2e-33 115.9 1.0 2.7e-33 115.5 1.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CBZ30672.1 - 6.6e-12 45.7 0.1 8.4e-12 45.4 0.1 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 CBZ30672.1 - 5.6e-05 22.7 0.1 0.00011 21.8 0.1 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 CBZ30672.1 - 0.0012 18.4 0.7 0.021 14.3 0.7 2.1 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 CBZ30672.1 - 0.044 12.9 0.3 0.052 12.7 0.3 1.4 1 1 0 1 1 1 0 Polysaccharide biosynthesis protein DUF1161 PF06649.12 CBZ30672.1 - 0.054 13.7 4.6 1.6 9.0 1.5 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1161) Sacchrp_dh_NADP PF03435.18 CBZ30672.1 - 0.09 13.0 0.8 0.12 12.6 0.6 1.5 1 1 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain adh_short PF00106.25 CBZ30673.1 - 1.4e-35 122.6 0.0 3.8e-35 121.1 0.0 1.6 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CBZ30673.1 - 5.7e-22 78.4 0.0 1.7e-21 76.8 0.0 1.8 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CBZ30673.1 - 9.1e-06 25.7 0.0 1.6e-05 24.9 0.0 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 CBZ30673.1 - 4.3e-05 23.1 0.0 7.5e-05 22.3 0.0 1.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Methyltransf_15 PF09445.10 CBZ30673.1 - 0.11 12.0 0.0 0.22 11.1 0.0 1.5 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase HTH_Tnp_Tc3_1 PF11427.8 CBZ30674.1 - 0.045 13.6 0.3 0.39 10.6 0.1 2.8 3 0 0 3 3 3 0 Tc3 transposase HrcA_DNA-bdg PF03444.15 CBZ30674.1 - 0.05 13.3 0.7 0.75 9.5 0.2 2.8 3 0 0 3 3 3 0 Winged helix-turn-helix transcription repressor, HrcA DNA-binding Glutaredoxin PF00462.24 CBZ30675.1 - 5.9e-17 61.6 1.7 3.8e-12 46.2 0.1 3.2 2 1 1 3 3 3 2 Glutaredoxin Thioredoxin PF00085.20 CBZ30675.1 - 1.1e-12 47.9 0.0 2.7e-12 46.6 0.0 1.7 2 0 0 2 2 2 1 Thioredoxin Thioredoxin_7 PF13899.6 CBZ30675.1 - 0.0027 17.8 0.0 0.0053 16.9 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin-like OST3_OST6 PF04756.13 CBZ30675.1 - 0.0037 16.7 0.0 0.0043 16.4 0.0 1.2 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin_8 PF13905.6 CBZ30675.1 - 0.016 15.5 0.0 0.033 14.5 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin-like AhpC-TSA PF00578.21 CBZ30675.1 - 0.045 13.7 0.0 0.077 12.9 0.0 1.5 1 0 0 1 1 1 0 AhpC/TSA family Thioredoxin_3 PF13192.6 CBZ30675.1 - 0.069 13.2 0.1 0.97 9.5 0.2 2.3 2 0 0 2 2 2 0 Thioredoxin domain Redoxin PF08534.10 CBZ30675.1 - 0.17 11.6 0.1 0.29 10.8 0.1 1.4 1 0 0 1 1 1 0 Redoxin AAA PF00004.29 CBZ30676.1 - 7e-36 123.6 0.0 1.7e-35 122.3 0.0 1.7 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 CBZ30676.1 - 8e-08 32.4 0.0 2e-07 31.1 0.0 1.7 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_lid_3 PF17862.1 CBZ30676.1 - 1.9e-07 30.7 0.0 5e-07 29.4 0.0 1.7 1 0 0 1 1 1 1 AAA+ lid domain RuvB_N PF05496.12 CBZ30676.1 - 4.3e-07 29.8 0.0 1.5e-06 28.0 0.0 1.8 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 CBZ30676.1 - 6.1e-07 30.0 0.3 2.2e-05 24.9 0.1 2.6 2 1 1 3 3 2 1 AAA ATPase domain TIP49 PF06068.13 CBZ30676.1 - 2.3e-06 27.1 0.0 1.2e-05 24.7 0.0 2.1 1 1 1 2 2 2 1 TIP49 P-loop domain AAA_22 PF13401.6 CBZ30676.1 - 8.2e-06 26.1 0.1 0.0014 18.9 0.0 2.6 1 1 0 2 2 2 1 AAA domain AAA_33 PF13671.6 CBZ30676.1 - 1.4e-05 25.3 0.0 3e-05 24.2 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.6 CBZ30676.1 - 4.9e-05 23.9 0.0 9.6e-05 22.9 0.0 1.7 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 CBZ30676.1 - 0.00017 21.4 0.0 0.00036 20.3 0.0 1.7 2 0 0 2 2 1 1 IstB-like ATP binding protein RNA_helicase PF00910.22 CBZ30676.1 - 0.00043 20.6 0.0 0.00092 19.6 0.0 1.7 1 0 0 1 1 1 1 RNA helicase Zeta_toxin PF06414.12 CBZ30676.1 - 0.0013 18.0 0.0 0.0061 15.9 0.0 2.1 3 0 0 3 3 3 1 Zeta toxin TsaE PF02367.17 CBZ30676.1 - 0.0017 18.3 0.0 0.0033 17.4 0.0 1.4 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_14 PF13173.6 CBZ30676.1 - 0.0019 18.3 0.0 0.0035 17.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.6 CBZ30676.1 - 0.0025 17.6 0.0 0.0043 16.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.6 CBZ30676.1 - 0.0025 18.1 0.2 0.0083 16.4 0.0 1.9 2 0 0 2 2 2 1 AAA domain SKI PF01202.22 CBZ30676.1 - 0.0029 17.7 0.0 0.017 15.3 0.0 2.1 2 0 0 2 2 2 1 Shikimate kinase Mg_chelatase PF01078.21 CBZ30676.1 - 0.0032 16.9 0.0 0.0059 16.0 0.0 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_7 PF12775.7 CBZ30676.1 - 0.0038 16.8 0.0 0.011 15.2 0.0 1.8 1 1 0 1 1 1 1 P-loop containing dynein motor region AAA_3 PF07726.11 CBZ30676.1 - 0.0057 16.5 0.0 0.013 15.4 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_2 PF07724.14 CBZ30676.1 - 0.01 16.0 0.0 0.022 14.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) Sigma54_activat PF00158.26 CBZ30676.1 - 0.011 15.4 0.0 0.038 13.7 0.0 1.9 2 1 0 2 2 2 0 Sigma-54 interaction domain Rad17 PF03215.15 CBZ30676.1 - 0.011 15.6 0.0 0.02 14.8 0.0 1.5 1 0 0 1 1 1 0 Rad17 P-loop domain NACHT PF05729.12 CBZ30676.1 - 0.017 15.0 0.0 0.037 14.0 0.0 1.6 1 1 0 1 1 1 0 NACHT domain Parvo_NS1 PF01057.17 CBZ30676.1 - 0.021 13.9 0.0 0.039 13.1 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Cytidylate_kin PF02224.18 CBZ30676.1 - 0.023 14.4 0.1 0.082 12.6 0.0 1.9 2 0 0 2 2 2 0 Cytidylate kinase Sigma54_activ_2 PF14532.6 CBZ30676.1 - 0.025 14.7 0.0 0.062 13.4 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_29 PF13555.6 CBZ30676.1 - 0.031 14.0 0.0 0.081 12.7 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF815 PF05673.13 CBZ30676.1 - 0.034 13.3 0.0 0.097 11.8 0.0 1.9 2 1 0 2 2 2 0 Protein of unknown function (DUF815) AAA_25 PF13481.6 CBZ30676.1 - 0.042 13.4 0.3 0.14 11.7 0.1 2.0 1 1 1 2 2 2 0 AAA domain AAA_17 PF13207.6 CBZ30676.1 - 0.053 14.0 0.0 0.12 12.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.6 CBZ30676.1 - 0.057 13.2 0.0 0.082 12.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain PhoH PF02562.16 CBZ30676.1 - 0.073 12.5 0.0 0.14 11.5 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein AAA_6 PF12774.7 CBZ30676.1 - 0.074 12.0 0.0 0.12 11.3 0.0 1.2 1 0 0 1 1 1 0 Hydrolytic ATP binding site of dynein motor region ABC_tran PF00005.27 CBZ30676.1 - 0.075 13.5 0.1 1.6 9.2 0.0 2.4 1 1 1 2 2 2 0 ABC transporter PPV_E1_C PF00519.17 CBZ30676.1 - 0.084 11.7 0.0 0.15 10.9 0.0 1.3 1 0 0 1 1 1 0 Papillomavirus helicase DUF2075 PF09848.9 CBZ30676.1 - 0.14 11.3 0.0 0.21 10.8 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) MMR_HSR1 PF01926.23 CBZ30676.1 - 0.18 11.9 0.1 1.9 8.6 0.0 2.3 2 1 0 2 2 2 0 50S ribosome-binding GTPase 2OG-FeII_Oxy_2 PF13532.6 CBZ30678.1 - 3.2e-08 34.0 0.0 4.5e-08 33.5 0.0 1.2 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.20 CBZ30678.1 - 0.014 15.9 0.0 0.12 12.9 0.0 2.2 2 0 0 2 2 2 0 2OG-Fe(II) oxygenase superfamily UQ_con PF00179.26 CBZ30680.1 - 2.6e-54 182.7 0.0 2.9e-54 182.5 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 CBZ30680.1 - 0.0065 16.8 0.0 0.0077 16.5 0.0 1.3 1 0 0 1 1 1 1 RWD domain Prok-E2_B PF14461.6 CBZ30680.1 - 0.14 11.9 0.0 0.16 11.7 0.0 1.2 1 0 0 1 1 1 0 Prokaryotic E2 family B CENP-T_C PF15511.6 CBZ30681.1 - 1e-06 28.8 0.1 1.5e-06 28.3 0.1 1.3 1 1 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CBFD_NFYB_HMF PF00808.23 CBZ30681.1 - 9.5e-05 22.6 0.8 0.00011 22.5 0.1 1.4 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TAF PF02969.17 CBZ30681.1 - 0.0002 21.5 0.2 0.00032 20.8 0.2 1.3 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) Bromo_TP PF07524.13 CBZ30681.1 - 0.00061 19.7 0.0 0.00077 19.4 0.0 1.2 1 0 0 1 1 1 1 Bromodomain associated Histone PF00125.24 CBZ30681.1 - 0.0034 17.7 2.2 0.0064 16.9 2.2 1.5 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID-31kDa PF02291.15 CBZ30681.1 - 0.011 15.8 0.0 0.014 15.4 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit PCP_red PF08369.10 CBZ30681.1 - 0.18 12.0 1.6 0.46 10.7 0.1 2.3 2 1 0 2 2 2 0 Proto-chlorophyllide reductase 57 kD subunit Thioredoxin PF00085.20 CBZ30683.1 - 4.3e-14 52.4 0.0 1.1e-13 51.0 0.0 1.7 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 CBZ30683.1 - 0.0062 17.0 1.1 0.12 12.9 0.6 2.9 2 1 0 2 2 2 1 Thioredoxin-like domain OST3_OST6 PF04756.13 CBZ30683.1 - 0.013 14.9 0.3 0.04 13.3 0.1 1.9 2 1 0 2 2 2 0 OST3 / OST6 family, transporter family TraF PF13728.6 CBZ30683.1 - 0.02 14.7 0.0 0.061 13.1 0.0 1.7 2 0 0 2 2 2 0 F plasmid transfer operon protein Thioredoxin_6 PF13848.6 CBZ30683.1 - 0.056 13.4 0.1 9.2 6.1 0.0 2.7 2 1 0 2 2 2 0 Thioredoxin-like domain Thioredoxin_8 PF13905.6 CBZ30683.1 - 0.056 13.8 0.0 0.32 11.3 0.0 2.4 2 1 0 2 2 2 0 Thioredoxin-like zf-CDGSH PF09360.10 CBZ30687.1 - 3.8e-19 68.6 6.8 1e-09 38.5 0.5 2.2 2 0 0 2 2 2 2 Iron-binding zinc finger CDGSH type Imm43 PF15570.6 CBZ30687.1 - 0.053 13.6 0.0 0.11 12.5 0.0 1.5 1 1 1 2 2 2 0 Immunity protein 43 DUF4379 PF14311.6 CBZ30687.1 - 0.11 12.9 2.9 1.6 9.2 0.1 2.6 2 1 0 2 2 2 0 Probable Zinc-ribbon domain Peptidase_M16 PF00675.20 CBZ30688.1 - 1.8e-28 99.4 0.0 3e-28 98.7 0.0 1.3 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 CBZ30688.1 - 3.6e-14 53.2 0.0 1.7e-13 51.0 0.0 2.0 2 0 0 2 2 2 1 Peptidase M16 inactive domain OTU PF02338.19 CBZ30689.1 - 2.2e-15 57.3 0.0 4e-15 56.4 0.0 1.4 1 0 0 1 1 1 1 OTU-like cysteine protease zf-RanBP PF00641.18 CBZ30689.1 - 7.9e-06 25.1 1.4 7.9e-06 25.1 1.4 5.1 4 1 1 5 5 5 1 Zn-finger in Ran binding protein and others Peptidase_C65 PF10275.9 CBZ30689.1 - 0.0019 17.7 0.0 0.15 11.5 0.0 2.4 1 1 0 2 2 2 1 Peptidase C65 Otubain zf-tcix PF14952.6 CBZ30689.1 - 0.036 13.7 0.4 0.036 13.7 0.4 3.8 3 0 0 3 3 3 0 Putative treble-clef, zinc-finger, Zn-binding zf-ribbon_3 PF13248.6 CBZ30689.1 - 0.11 11.9 0.0 0.11 11.9 0.0 4.1 4 0 0 4 4 4 0 zinc-ribbon domain RecR PF02132.15 CBZ30689.1 - 0.4 10.3 16.3 3.7 7.2 0.4 4.3 4 1 0 4 4 4 0 RecR protein DZR PF12773.7 CBZ30689.1 - 0.81 9.8 30.2 0.52 10.4 5.9 4.2 3 1 0 3 3 3 0 Double zinc ribbon RRM_1 PF00076.22 CBZ30690.1 - 1.4e-06 28.0 0.0 0.059 13.2 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) tRNA-synt_2b PF00587.25 CBZ30691.1 - 1.4e-30 106.6 0.0 1.8e-27 96.5 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 CBZ30691.1 - 6.2e-17 61.5 0.1 1.2e-16 60.6 0.1 1.5 1 0 0 1 1 1 1 Anticodon binding domain TGS PF02824.21 CBZ30691.1 - 3.2e-13 49.5 0.0 6.1e-13 48.6 0.0 1.5 1 0 0 1 1 1 1 TGS domain tRNA_SAD PF07973.14 CBZ30691.1 - 2e-11 43.8 0.0 3.5e-11 43.0 0.0 1.4 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain TPR_1 PF00515.28 CBZ30692.1 - 1e-23 82.1 4.6 1.5e-06 27.8 0.0 6.2 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_11 PF13414.6 CBZ30692.1 - 4.8e-21 74.2 3.6 3.7e-06 26.5 0.0 5.4 3 2 2 5 5 5 3 TPR repeat TPR_2 PF07719.17 CBZ30692.1 - 1.6e-20 71.5 9.5 3.1e-05 23.8 0.0 6.9 7 0 0 7 7 6 5 Tetratricopeptide repeat TPR_17 PF13431.6 CBZ30692.1 - 2.5e-20 71.3 2.9 2.1e-05 24.6 0.5 5.1 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_16 PF13432.6 CBZ30692.1 - 3.4e-18 66.0 4.6 3e-08 34.2 0.1 4.5 2 2 3 5 5 5 4 Tetratricopeptide repeat TPR_14 PF13428.6 CBZ30692.1 - 2.3e-15 56.0 14.3 4e-05 24.1 0.0 7.0 4 2 4 8 8 6 4 Tetratricopeptide repeat TPR_8 PF13181.6 CBZ30692.1 - 3.6e-14 51.7 4.0 0.0039 17.3 0.0 6.6 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_19 PF14559.6 CBZ30692.1 - 8.9e-13 48.6 12.8 1.9e-06 28.3 0.2 4.8 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_7 PF13176.6 CBZ30692.1 - 2.6e-09 36.5 0.1 0.3 11.2 0.0 5.3 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_12 PF13424.6 CBZ30692.1 - 4e-08 33.4 1.4 0.00011 22.4 0.0 4.5 3 1 2 5 5 5 3 Tetratricopeptide repeat TPR_9 PF13371.6 CBZ30692.1 - 3.2e-06 27.2 1.8 0.23 11.6 0.1 3.6 2 1 0 3 3 3 2 Tetratricopeptide repeat TPR_6 PF13174.6 CBZ30692.1 - 0.00052 20.5 11.7 1 10.2 0.0 6.5 7 0 0 7 7 6 1 Tetratricopeptide repeat TPR_10 PF13374.6 CBZ30692.1 - 0.0038 17.0 14.6 1.2 9.1 0.5 5.1 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_20 PF14561.6 CBZ30692.1 - 0.0067 16.7 14.4 1.5 9.2 0.2 5.2 3 1 2 5 5 5 1 Tetratricopeptide repeat ChAPs PF09295.10 CBZ30692.1 - 0.034 13.1 1.9 1.1 8.2 0.0 2.6 2 1 0 2 2 2 0 ChAPs (Chs5p-Arf1p-binding proteins) ANAPC3 PF12895.7 CBZ30692.1 - 0.08 13.2 1.3 0.27 11.5 0.1 2.4 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TFIIA PF03153.13 CBZ30692.1 - 0.093 12.7 23.2 0.15 12.1 23.2 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Fis1_TPR_C PF14853.6 CBZ30692.1 - 0.1 12.7 2.2 4.8 7.3 0.1 4.0 4 0 0 4 4 4 0 Fis1 C-terminal tetratricopeptide repeat BTAD PF03704.17 CBZ30692.1 - 2.5 8.5 7.5 7 7.1 0.1 3.3 3 1 1 4 4 3 0 Bacterial transcriptional activator domain Ribosomal_L2_C PF03947.18 CBZ30693.1 - 6.8e-43 145.9 3.7 1.2e-42 145.1 2.1 1.9 2 0 0 2 2 2 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.23 CBZ30693.1 - 5.2e-13 48.7 0.0 1.5e-12 47.3 0.0 1.8 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain Ribosomal_L2_C PF03947.18 CBZ30694.1 - 6.8e-43 145.9 3.7 1.2e-42 145.1 2.1 1.9 2 0 0 2 2 2 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.23 CBZ30694.1 - 5.2e-13 48.7 0.0 1.5e-12 47.3 0.0 1.8 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain RasGAP_C PF03836.15 CBZ30695.1 - 9.5 6.4 10.8 1.5 9.0 0.5 3.5 2 0 0 2 2 2 0 RasGAP C-terminus Choline_kinase PF01633.20 CBZ30697.1 - 4.5e-31 108.1 0.1 2.9e-30 105.5 0.1 2.0 1 1 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.23 CBZ30697.1 - 9.8e-11 42.0 0.0 3.4e-08 33.7 0.0 2.6 2 1 0 2 2 2 2 Phosphotransferase enzyme family Arginase PF00491.21 CBZ30698.1 - 1.1e-74 251.5 0.0 1.3e-74 251.2 0.0 1.0 1 0 0 1 1 1 1 Arginase family NIF PF03031.18 CBZ30700.1 - 1.7e-20 73.4 0.0 3e-20 72.6 0.0 1.3 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase zf-CCCH PF00642.24 CBZ30700.1 - 1.2e-05 25.1 2.0 2.3e-05 24.2 2.0 1.5 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 CBZ30700.1 - 0.00063 19.7 0.3 0.0014 18.6 0.3 1.5 1 0 0 1 1 1 1 Zinc finger domain BRK PF07533.16 CBZ30700.1 - 0.059 13.0 0.0 16 5.2 0.0 2.5 2 0 0 2 2 2 0 BRK domain Myosin_N PF02736.19 CBZ30700.1 - 0.17 11.7 0.6 0.35 10.7 0.6 1.5 1 0 0 1 1 1 0 Myosin N-terminal SH3-like domain Rieske PF00355.26 CBZ30703.1 - 1.2e-12 47.5 0.0 2.2e-12 46.7 0.0 1.4 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain cEGF PF12662.7 CBZ30705.1 - 0.16 11.9 0.3 0.35 10.8 0.3 1.5 1 0 0 1 1 1 0 Complement Clr-like EGF-like Methyltransf_23 PF13489.6 CBZ30706.1 - 1.7e-19 70.2 0.0 2.6e-19 69.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CBZ30706.1 - 1.6e-12 47.9 0.0 2.9e-12 47.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CBZ30706.1 - 6e-11 42.9 0.0 1.2e-10 42.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 CBZ30706.1 - 3.4e-09 36.4 0.0 4.5e-09 36.0 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.6 CBZ30706.1 - 2.8e-07 30.5 0.0 4.4e-07 29.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CBZ30706.1 - 3.8e-07 30.8 0.0 8e-07 29.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain AsnC_trans_reg PF01037.21 CBZ30706.1 - 0.15 12.0 0.0 0.38 10.7 0.0 1.6 1 0 0 1 1 1 0 Lrp/AsnC ligand binding domain Peptidase_C14 PF00656.22 CBZ30707.1 - 3.5e-48 164.7 0.0 4.4e-48 164.4 0.0 1.1 1 0 0 1 1 1 1 Caspase domain CENP-F_leu_zip PF10473.9 CBZ30708.1 - 3.2 7.8 9.8 3.4 7.7 2.6 2.4 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Nucleopor_Nup85 PF07575.13 CBZ30709.1 - 0.03 12.9 0.1 0.049 12.2 0.1 1.2 1 0 0 1 1 1 0 Nup85 Nucleoporin Laminin_G_3 PF13385.6 CBZ30711.1 - 1.5e-12 47.9 0.0 4.8e-12 46.3 0.0 1.9 2 0 0 2 2 2 1 Concanavalin A-like lectin/glucanases superfamily DUF2972 PF11186.8 CBZ30711.1 - 0.53 10.2 2.9 0.29 11.0 0.2 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2972) EF-hand_7 PF13499.6 CBZ30712.1 - 0.0016 18.9 0.0 0.0038 17.7 0.0 1.6 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.32 CBZ30712.1 - 0.0022 17.4 0.0 0.28 10.8 0.0 2.5 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 CBZ30712.1 - 0.011 15.6 0.0 1.4 9.1 0.0 2.7 2 0 0 2 2 2 0 EF-hand domain NYD-SP28_assoc PF14775.6 CBZ30714.1 - 0.1 12.7 0.2 0.1 12.7 0.2 5.8 6 1 1 7 7 7 0 Sperm tail C-terminal domain MutL_C PF08676.11 CBZ30715.1 - 2.6e-28 98.6 0.0 6.3e-28 97.4 0.0 1.7 1 0 0 1 1 1 1 MutL C terminal dimerisation domain DNA_mis_repair PF01119.19 CBZ30715.1 - 2.2e-10 40.2 0.0 3.9e-10 39.5 0.0 1.4 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.6 CBZ30715.1 - 1.5e-07 31.3 2.6 7.4e-07 29.1 0.3 2.7 3 0 0 3 3 3 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 CBZ30715.1 - 0.00012 22.6 0.1 0.00047 20.6 0.0 2.1 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Ribosomal_L26 PF16906.5 CBZ30716.1 - 3.1e-37 126.9 1.6 3.9e-37 126.6 1.6 1.1 1 0 0 1 1 1 1 Ribosomal proteins L26 eukaryotic, L24P archaeal KOW PF00467.29 CBZ30716.1 - 1.2e-06 28.3 1.1 3e-06 27.0 1.1 1.8 1 1 0 1 1 1 1 KOW motif LRR_4 PF12799.7 CBZ30718.1 - 4.3e-14 52.4 9.6 4.6e-05 23.7 0.1 4.6 3 1 0 4 4 4 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CBZ30718.1 - 6.7e-13 48.2 17.6 0.00037 20.2 0.5 4.6 2 2 2 4 4 4 4 Leucine rich repeat LRR_1 PF00560.33 CBZ30718.1 - 5.2e-07 29.3 8.3 2.6 8.9 0.0 6.9 6 1 0 6 6 6 2 Leucine Rich Repeat LRR_6 PF13516.6 CBZ30718.1 - 7.2e-05 22.5 12.5 5.8 7.2 0.2 6.9 7 0 0 7 7 7 2 Leucine Rich repeat KLRAQ PF10205.9 CBZ30718.1 - 0.023 14.9 3.4 0.023 14.9 3.4 2.1 2 1 0 2 2 2 0 Predicted coiled-coil domain-containing protein DUF812 PF05667.11 CBZ30718.1 - 0.05 12.5 11.8 0.067 12.1 11.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF812) FlaC_arch PF05377.11 CBZ30718.1 - 0.11 12.9 0.5 0.11 12.9 0.5 2.4 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) Spc29 PF17082.5 CBZ30718.1 - 0.13 12.1 6.0 0.022 14.6 2.2 1.7 2 0 0 2 2 2 0 Spindle Pole Component 29 Macoilin PF09726.9 CBZ30718.1 - 0.18 10.3 11.5 0.23 10.0 11.5 1.1 1 0 0 1 1 1 0 Macoilin family GIT_CC PF16559.5 CBZ30718.1 - 0.93 9.4 12.1 0.13 12.1 2.1 3.6 3 1 0 3 3 3 0 GIT coiled-coil Rho guanine nucleotide exchange factor Takusan PF04822.13 CBZ30718.1 - 1.4 8.9 6.8 5.3 7.0 6.8 2.0 1 1 0 1 1 1 0 Takusan RTC PF01137.21 CBZ30719.1 - 2.1e-41 141.6 0.2 2.4e-41 141.4 0.2 1.0 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase RTC_insert PF05189.13 CBZ30719.1 - 1.7e-26 92.7 0.1 2.7e-26 92.1 0.1 1.3 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase (RTC), insert domain Pro_isomerase PF00160.21 CBZ30720.1 - 5.1e-09 36.6 0.0 8.2e-09 35.9 0.0 1.3 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Pkinase PF00069.25 CBZ30721.1 - 1e-58 198.8 0.0 1.2e-58 198.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ30721.1 - 5e-18 65.3 0.0 8.8e-18 64.5 0.0 1.3 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 CBZ30721.1 - 1.1e-05 25.5 0.0 0.00094 19.2 0.0 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family UCH PF00443.29 CBZ30722.1 - 3.7e-49 167.6 0.2 6.2e-49 166.8 0.2 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 CBZ30722.1 - 1.6e-20 74.0 0.1 1.4e-18 67.6 0.1 3.0 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase USP7_ICP0_bdg PF12436.8 CBZ30722.1 - 4.5e-10 39.2 0.0 1.2e-09 37.8 0.0 1.7 2 0 0 2 2 2 1 ICP0-binding domain of Ubiquitin-specific protease 7 USP7_C2 PF14533.6 CBZ30722.1 - 9.4e-10 38.5 0.0 3.6e-09 36.6 0.0 2.0 1 1 0 1 1 1 1 Ubiquitin-specific protease C-terminal Robl_LC7 PF03259.17 CBZ30723.1 - 1.4e-19 69.7 0.0 1.7e-19 69.3 0.0 1.1 1 0 0 1 1 1 1 Roadblock/LC7 domain LAMTOR5 PF16672.5 CBZ30723.1 - 1.9e-06 27.7 0.0 2.6e-06 27.2 0.0 1.2 1 0 0 1 1 1 1 Ragulator complex protein LAMTOR5 Epimerase_2 PF02350.19 CBZ30723.1 - 0.012 14.5 0.1 0.016 14.1 0.1 1.1 1 0 0 1 1 1 0 UDP-N-acetylglucosamine 2-epimerase CRM1_repeat_2 PF18784.1 CBZ30723.1 - 0.05 13.3 0.0 0.09 12.4 0.0 1.4 1 0 0 1 1 1 0 CRM1 / Exportin repeat 2 SPOUT_MTase_2 PF14419.6 CBZ30723.1 - 0.12 11.7 0.0 0.18 11.2 0.0 1.3 1 0 0 1 1 1 0 AF2226-like SPOUT RNA Methylase fused to THUMP Glyco_hydro_38 PF18438.1 CBZ30723.1 - 0.16 12.0 0.0 0.23 11.5 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolases family 38 C-terminal domain 1 Peptidase_M57 PF12388.8 CBZ30724.1 - 0.1 12.2 0.1 0.18 11.3 0.1 1.4 1 1 0 1 1 1 0 Dual-action HEIGH metallo-peptidase Proteasom_Rpn13 PF04683.13 CBZ30725.1 - 3.6e-14 53.1 0.1 5.6e-14 52.5 0.1 1.3 1 0 0 1 1 1 1 Proteasome complex subunit Rpn13 ubiquitin receptor RPN13_C PF16550.5 CBZ30725.1 - 3.5e-10 40.1 0.0 5e-10 39.5 0.0 1.3 1 0 0 1 1 1 1 UCH-binding domain DUF737 PF05300.11 CBZ30726.1 - 0.0064 16.9 2.0 0.0065 16.9 2.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF737) YabA PF06156.13 CBZ30726.1 - 0.051 14.2 3.1 0.051 14.2 3.1 2.2 1 1 0 2 2 2 0 Initiation control protein YabA Pox_MCEL PF03291.16 CBZ30726.1 - 0.055 12.6 1.6 0.09 11.9 0.6 1.6 1 1 1 2 2 2 0 mRNA capping enzyme DivIC PF04977.15 CBZ30726.1 - 5 7.0 9.4 0.55 10.0 2.1 2.3 1 1 1 2 2 2 0 Septum formation initiator DNA_pol_E_B PF04042.16 CBZ30727.1 - 1.9e-22 79.7 0.0 3.2e-22 78.9 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B DTW PF03942.15 CBZ30728.1 - 2.7e-22 79.5 0.2 4.6e-22 78.7 0.2 1.4 1 0 0 1 1 1 1 DTW domain C1_4 PF07975.12 CBZ30728.1 - 0.074 13.3 0.4 0.15 12.3 0.4 1.5 1 0 0 1 1 1 0 TFIIH C1-like domain zinc_ribbon_9 PF14369.6 CBZ30728.1 - 1.1 9.6 4.8 4.6 7.6 0.4 2.5 1 1 1 2 2 2 0 zinc-ribbon GAS PF13851.6 CBZ30729.1 - 1.6e-58 197.4 26.4 1.6e-58 197.4 26.4 3.1 2 1 0 2 2 2 1 Growth-arrest specific micro-tubule binding DUF948 PF06103.11 CBZ30729.1 - 0.43 10.9 12.8 1.5 9.2 0.6 4.7 2 2 1 4 4 4 0 Bacterial protein of unknown function (DUF948) DDE_Tnp_4 PF13359.6 CBZ30729.1 - 3.1 7.5 6.1 2.5 7.8 0.7 2.6 1 1 1 2 2 2 0 DDE superfamily endonuclease Ebp2 PF05890.12 CBZ30730.1 - 4.1e-45 154.4 13.6 6.1e-45 153.9 13.6 1.2 1 0 0 1 1 1 1 Eukaryotic rRNA processing protein EBP2 Lysine_decarbox PF03641.14 CBZ30731.1 - 0.11 12.6 0.0 0.24 11.5 0.0 1.6 1 0 0 1 1 1 0 Possible lysine decarboxylase DUF5527 PF17665.1 CBZ30732.1 - 0.02 14.4 0.1 0.027 14.0 0.1 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5527) Baculo_IE-1 PF05290.11 CBZ30732.1 - 0.032 14.2 0.3 0.037 14.0 0.3 1.2 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) EMP24_GP25L PF01105.24 CBZ30733.1 - 1.9e-39 135.5 0.2 2.5e-39 135.1 0.2 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD MogR_DNAbind PF12181.8 CBZ30733.1 - 0.12 12.3 0.7 0.18 11.7 0.7 1.2 1 0 0 1 1 1 0 DNA binding domain of the motility gene repressor (MogR) Pkinase PF00069.25 CBZ30734.1 - 6.7e-52 176.4 0.0 8.7e-52 176.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ30734.1 - 2.7e-21 76.0 0.0 5.6e-21 75.0 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 CBZ30734.1 - 0.021 14.1 0.5 3.5 6.8 0.0 2.4 1 1 1 2 2 2 0 Kinase-like APH PF01636.23 CBZ30734.1 - 0.091 12.7 0.2 0.34 10.8 0.1 1.7 1 1 1 2 2 2 0 Phosphotransferase enzyme family TRAF_BIRC3_bd PF16673.5 CBZ30735.1 - 0.014 15.2 0.2 0.029 14.2 0.2 1.5 1 0 0 1 1 1 0 TNF receptor-associated factor BIRC3 binding domain Uds1 PF15456.6 CBZ30735.1 - 0.079 13.1 2.0 0.098 12.8 0.3 2.1 2 0 0 2 2 2 0 Up-regulated During Septation GAF_2 PF13185.6 CBZ30735.1 - 0.11 12.8 2.4 0.67 10.2 0.4 3.3 2 2 1 3 3 3 0 GAF domain Ribosomal_L5e PF17144.4 CBZ30736.1 - 2.5e-76 255.2 0.7 4e-76 254.5 0.7 1.3 1 0 0 1 1 1 1 Ribosomal large subunit proteins 60S L5, and 50S L18 Ribosomal_L18_c PF14204.6 CBZ30736.1 - 3.3e-26 92.1 7.1 3.3e-26 92.1 7.1 1.9 2 0 0 2 2 2 1 Ribosomal L18 C-terminal region P53_C PF11619.8 CBZ30736.1 - 0.00081 19.4 0.0 0.98 9.5 0.0 2.5 2 0 0 2 2 2 2 Transcription factor P53 - C terminal domain Ribosomal_L18p PF00861.22 CBZ30736.1 - 0.013 15.9 1.3 0.022 15.1 0.0 2.0 2 0 0 2 2 2 0 Ribosomal L18 of archaea, bacteria, mitoch. and chloroplast SIP1 PF04938.12 CBZ30736.1 - 0.16 11.6 0.9 0.27 10.9 0.9 1.3 1 0 0 1 1 1 0 Survival motor neuron (SMN) interacting protein 1 (SIP1) Ribosomal_L5e PF17144.4 CBZ30737.1 - 2.5e-76 255.2 0.7 4e-76 254.5 0.7 1.3 1 0 0 1 1 1 1 Ribosomal large subunit proteins 60S L5, and 50S L18 Ribosomal_L18_c PF14204.6 CBZ30737.1 - 3.3e-26 92.1 7.1 3.3e-26 92.1 7.1 1.9 2 0 0 2 2 2 1 Ribosomal L18 C-terminal region P53_C PF11619.8 CBZ30737.1 - 0.00081 19.4 0.0 0.98 9.5 0.0 2.5 2 0 0 2 2 2 2 Transcription factor P53 - C terminal domain Ribosomal_L18p PF00861.22 CBZ30737.1 - 0.013 15.9 1.3 0.022 15.1 0.0 2.0 2 0 0 2 2 2 0 Ribosomal L18 of archaea, bacteria, mitoch. and chloroplast SIP1 PF04938.12 CBZ30737.1 - 0.16 11.6 0.9 0.27 10.9 0.9 1.3 1 0 0 1 1 1 0 Survival motor neuron (SMN) interacting protein 1 (SIP1) Ribosomal_L5e PF17144.4 CBZ30738.1 - 2.5e-76 255.2 0.7 4e-76 254.5 0.7 1.3 1 0 0 1 1 1 1 Ribosomal large subunit proteins 60S L5, and 50S L18 Ribosomal_L18_c PF14204.6 CBZ30738.1 - 3.3e-26 92.1 7.1 3.3e-26 92.1 7.1 1.9 2 0 0 2 2 2 1 Ribosomal L18 C-terminal region P53_C PF11619.8 CBZ30738.1 - 0.00081 19.4 0.0 0.98 9.5 0.0 2.5 2 0 0 2 2 2 2 Transcription factor P53 - C terminal domain Ribosomal_L18p PF00861.22 CBZ30738.1 - 0.013 15.9 1.3 0.022 15.1 0.0 2.0 2 0 0 2 2 2 0 Ribosomal L18 of archaea, bacteria, mitoch. and chloroplast SIP1 PF04938.12 CBZ30738.1 - 0.16 11.6 0.9 0.27 10.9 0.9 1.3 1 0 0 1 1 1 0 Survival motor neuron (SMN) interacting protein 1 (SIP1) Ribosomal_L15e PF00827.17 CBZ30739.1 - 2.1e-84 282.0 8.4 2.5e-84 281.8 8.4 1.0 1 0 0 1 1 1 1 Ribosomal L15 Ribosomal_L36e PF01158.18 CBZ30740.1 - 1.5e-28 98.9 1.8 1.7e-28 98.7 1.8 1.0 1 0 0 1 1 1 1 Ribosomal protein L36e PHD PF00628.29 CBZ30742.1 - 0.00094 19.0 1.6 0.00094 19.0 1.6 2.0 2 0 0 2 2 2 1 PHD-finger PHD_Oberon PF07227.11 CBZ30742.1 - 0.15 11.9 4.8 0.65 9.9 3.3 2.1 2 0 0 2 2 2 0 PHD - plant homeodomain finger protein Prok-RING_1 PF14446.6 CBZ30742.1 - 0.18 11.7 5.9 0.38 10.7 5.9 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 C1_1 PF00130.22 CBZ30742.1 - 0.31 10.9 9.1 0.17 11.8 5.0 2.3 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Atg14 PF10186.9 CBZ30743.1 - 8.8e-05 21.7 2.2 0.00013 21.1 2.2 1.3 1 0 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 TMCO5 PF14992.6 CBZ30743.1 - 0.0039 16.8 4.5 0.0045 16.6 3.6 1.5 2 0 0 2 2 2 1 TMCO5 family UPF0184 PF03670.13 CBZ30743.1 - 0.2 12.0 5.0 0.073 13.5 1.8 1.9 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0184) CENP-H PF05837.12 CBZ30743.1 - 0.65 10.4 11.3 1.3 9.4 11.3 1.5 1 0 0 1 1 1 0 Centromere protein H (CENP-H) SHE3 PF17078.5 CBZ30743.1 - 0.85 9.3 7.5 1.4 8.5 7.5 1.3 1 0 0 1 1 1 0 SWI5-dependent HO expression protein 3 OmpH PF03938.14 CBZ30743.1 - 1.3 9.4 8.7 2.4 8.5 8.7 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) TMF_TATA_bd PF12325.8 CBZ30743.1 - 1.9 8.8 10.6 4 7.7 10.6 1.5 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding YabA PF06156.13 CBZ30743.1 - 2.6 8.7 9.5 8.7 7.1 2.3 2.5 1 1 1 2 2 2 0 Initiation control protein YabA DivIC PF04977.15 CBZ30743.1 - 2.8 7.8 8.6 8.4 6.2 0.5 2.3 2 0 0 2 2 2 0 Septum formation initiator DUF4407 PF14362.6 CBZ30743.1 - 3.8 6.8 9.1 1.3 8.3 1.9 2.2 1 1 2 3 3 3 0 Domain of unknown function (DUF4407) NYD-SP28_assoc PF14775.6 CBZ30743.1 - 4.3 7.5 11.6 1.4 9.1 2.3 2.4 1 1 1 2 2 2 0 Sperm tail C-terminal domain ATP11 PF06644.11 CBZ30744.1 - 2.3e-21 76.8 1.8 3.8e-21 76.1 1.8 1.3 1 0 0 1 1 1 1 ATP11 protein ABC_trans_N PF14510.6 CBZ30744.1 - 0.13 12.9 0.0 0.23 12.1 0.0 1.3 1 0 0 1 1 1 0 ABC-transporter N-terminal Lysine_decarbox PF03641.14 CBZ30745.1 - 9.7e-15 54.8 0.4 3.7e-14 53.0 0.0 1.8 1 1 1 2 2 2 1 Possible lysine decarboxylase LDcluster4 PF18306.1 CBZ30745.1 - 9.2e-11 41.6 1.1 4e-09 36.2 1.1 2.4 1 1 0 1 1 1 1 SLOG cluster4 family DUF4539 PF15072.6 CBZ30745.1 - 0.19 11.8 0.1 1.6 8.8 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4539) UBX PF00789.20 CBZ30746.1 - 9.9e-08 32.1 0.1 3.9e-07 30.2 0.0 1.9 2 0 0 2 2 2 1 UBX domain Thioredoxin_7 PF13899.6 CBZ30746.1 - 0.094 12.9 1.1 0.58 10.4 0.0 2.9 3 0 0 3 3 3 0 Thioredoxin-like Spore_coat_CotO PF14153.6 CBZ30746.1 - 0.7 9.8 8.9 2.4 8.0 9.4 1.6 2 0 0 2 2 2 0 Spore coat protein CotO TALPID3 PF15324.6 CBZ30746.1 - 1.5 6.4 10.8 2 6.0 10.8 1.0 1 0 0 1 1 1 0 Hedgehog signalling target Asp-B-Hydro_N PF05279.11 CBZ30746.1 - 2.1 8.3 15.1 3.3 7.7 15.1 1.2 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Presenilin PF01080.17 CBZ30746.1 - 2.8 6.6 5.8 3.6 6.2 5.8 1.1 1 0 0 1 1 1 0 Presenilin DUF572 PF04502.13 CBZ30746.1 - 4.3 6.9 11.9 6.3 6.3 11.9 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) CAP_N PF01213.19 CBZ30747.1 - 0.35 10.3 4.4 0.65 9.4 4.4 1.3 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal U3_assoc_6 PF08640.11 CBZ30748.1 - 3.1e-16 59.2 0.2 8.8e-16 57.7 0.1 1.9 2 0 0 2 2 2 1 U3 small nucleolar RNA-associated protein 6 DUF3446 PF11928.8 CBZ30749.1 - 2 8.8 11.6 0.55 10.6 1.8 3.9 2 0 0 2 2 2 0 Early growth response N-terminal domain Ribosomal_S6e PF01092.19 CBZ30750.1 - 9.4e-39 132.2 0.0 1.9e-38 131.2 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein S6e RdRP_3 PF00998.23 CBZ30750.1 - 0.056 12.1 6.0 0.067 11.9 6.0 1.1 1 0 0 1 1 1 0 Viral RNA dependent RNA polymerase WSK PF03832.13 CBZ30750.1 - 0.092 12.5 0.3 0.092 12.5 0.3 2.2 2 0 0 2 2 2 0 WSK motif RmlD_sub_bind PF04321.17 CBZ30751.1 - 9.1e-05 21.7 0.0 0.049 12.7 0.0 2.2 2 0 0 2 2 2 2 RmlD substrate binding domain Sulfatase_C PF14707.6 CBZ30751.1 - 0.15 12.8 0.0 0.31 11.8 0.0 1.5 1 0 0 1 1 1 0 C-terminal region of aryl-sulfatase AAA_lid_7 PF17867.1 CBZ30751.1 - 0.17 12.1 0.1 0.6 10.3 0.0 1.9 2 0 0 2 2 2 0 Midasin AAA lid domain EF-hand_6 PF13405.6 CBZ30752.1 - 6.6e-09 35.0 0.0 0.14 12.2 0.0 3.8 4 0 0 4 4 4 3 EF-hand domain EF-hand_1 PF00036.32 CBZ30752.1 - 2.4e-06 26.7 0.0 0.25 11.0 0.0 3.4 3 0 0 3 3 3 2 EF hand EF-hand_7 PF13499.6 CBZ30752.1 - 4.3e-06 27.1 0.0 0.27 11.7 0.0 3.5 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.6 CBZ30752.1 - 0.0071 15.8 0.0 0.49 10.0 0.2 2.5 2 0 0 2 2 2 1 EF hand EF-hand_8 PF13833.6 CBZ30752.1 - 0.059 13.2 0.3 9.5 6.2 0.0 2.7 2 0 0 2 2 2 0 EF-hand domain pair Ank_2 PF12796.7 CBZ30753.1 - 9.1e-65 215.3 19.7 4.3e-10 40.0 0.0 14.2 11 4 2 14 14 14 9 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CBZ30753.1 - 9.8e-36 121.7 23.2 0.00035 21.1 0.1 14.6 11 3 8 19 19 19 11 Ankyrin repeats (many copies) Ank_5 PF13857.6 CBZ30753.1 - 5.2e-32 109.5 39.4 9e-06 25.9 0.3 18.1 14 5 6 20 20 20 8 Ankyrin repeats (many copies) Ank_3 PF13606.6 CBZ30753.1 - 1.1e-26 90.0 38.4 0.015 15.7 0.0 20.3 22 0 0 22 22 22 8 Ankyrin repeat Ank PF00023.30 CBZ30753.1 - 2.7e-23 81.3 48.8 0.048 14.1 0.1 18.4 19 1 0 19 19 19 6 Ankyrin repeat TetR_C_36 PF18598.1 CBZ30753.1 - 0.019 14.9 0.3 0.08 12.9 0.3 2.1 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain Filamin PF00630.19 CBZ30753.1 - 0.073 13.9 0.0 0.38 11.6 0.0 2.1 2 0 0 2 2 2 0 Filamin/ABP280 repeat SUIM_assoc PF16619.5 CBZ30753.1 - 4.3 7.5 7.3 2.9 8.0 1.3 3.0 3 0 0 3 3 3 0 Unstructured region C-term to UIM in Ataxin3 Ribosomal_L32e PF01655.18 CBZ30754.1 - 1.7e-39 134.6 0.2 2e-39 134.3 0.2 1.1 1 0 0 1 1 1 1 Ribosomal protein L32 SH3_9 PF14604.6 CBZ30755.1 - 4.3e-32 109.7 0.4 2.7e-12 46.3 0.0 4.3 5 0 0 5 5 5 3 Variant SH3 domain SH3_1 PF00018.28 CBZ30755.1 - 3.8e-30 103.3 0.2 5.2e-12 45.2 0.0 3.4 3 0 0 3 3 3 3 SH3 domain SH3_2 PF07653.17 CBZ30755.1 - 5.6e-24 83.6 0.2 5.4e-12 45.2 0.1 3.8 4 0 0 4 4 4 3 Variant SH3 domain Evf PF18270.1 CBZ30755.1 - 0.06 12.8 0.0 0.25 10.7 0.0 1.8 2 0 0 2 2 2 0 Virulence factor Evf DUF4205 PF13898.6 CBZ30756.1 - 3.2e-23 82.2 0.0 5.8e-23 81.4 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4205) Macoilin PF09726.9 CBZ30756.1 - 0.63 8.5 8.1 0.98 7.9 8.1 1.4 1 0 0 1 1 1 0 Macoilin family E1-E2_ATPase PF00122.20 CBZ30758.1 - 7.1e-44 149.5 1.2 7.1e-44 149.5 1.2 2.0 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 CBZ30758.1 - 5.9e-27 94.5 2.0 5.9e-27 94.5 2.0 2.4 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 CBZ30758.1 - 7.9e-16 59.0 0.0 3.7e-14 53.5 0.0 3.2 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 CBZ30758.1 - 1.5e-14 53.8 0.1 4.3e-14 52.4 0.1 1.8 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 CBZ30758.1 - 1.5e-09 37.4 0.0 4e-09 36.0 0.0 1.8 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 CBZ30758.1 - 2.1e-05 24.4 2.3 3.8e-05 23.6 0.4 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Kinesin PF00225.23 CBZ30759.1 - 7.8e-73 245.3 0.0 3.1e-43 148.0 0.0 2.3 2 0 0 2 2 2 2 Kinesin motor domain Microtub_bd PF16796.5 CBZ30759.1 - 1.1e-22 80.6 0.0 2.9e-22 79.2 0.0 1.7 1 0 0 1 1 1 1 Microtubule binding Cob_adeno_trans PF01923.18 CBZ30759.1 - 0.079 13.1 1.2 10 6.2 0.3 2.6 2 0 0 2 2 2 0 Cobalamin adenosyltransferase Synaptobrevin PF00957.21 CBZ30762.1 - 5.1e-14 51.8 0.1 8.9e-14 51.1 0.1 1.4 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.6 CBZ30762.1 - 2.6e-06 27.4 0.0 4.4e-06 26.6 0.0 1.3 1 0 0 1 1 1 1 Regulated-SNARE-like domain SDA1 PF05285.12 CBZ30763.1 - 0.023 14.1 10.5 0.033 13.6 10.5 1.2 1 0 0 1 1 1 0 SDA1 BUD22 PF09073.10 CBZ30763.1 - 0.13 11.6 9.4 0.2 11.0 9.4 1.3 1 0 0 1 1 1 0 BUD22 Nop14 PF04147.12 CBZ30763.1 - 1.5 6.9 15.1 2.1 6.5 15.1 1.2 1 0 0 1 1 1 0 Nop14-like family PTPRCAP PF15713.5 CBZ30763.1 - 2 8.7 19.4 1.2 9.5 16.2 2.0 2 0 0 2 2 2 0 Protein tyrosine phosphatase receptor type C-associated TFIID-31kDa PF02291.15 CBZ30764.1 - 0.025 14.7 0.0 0.05 13.7 0.0 1.5 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Lipase_3 PF01764.25 CBZ30765.1 - 2.7e-05 24.1 0.0 9.4e-05 22.3 0.0 1.9 2 0 0 2 2 2 1 Lipase (class 3) PGAP1 PF07819.13 CBZ30765.1 - 0.0017 18.1 0.0 0.0033 17.2 0.0 1.4 1 0 0 1 1 1 1 PGAP1-like protein KIAA1430 PF13879.6 CBZ30765.1 - 0.095 13.5 1.2 16 6.3 0.1 2.3 2 0 0 2 2 2 0 KIAA1430 homologue adh_short PF00106.25 CBZ30766.1 - 8.9e-17 61.2 0.1 1.3e-14 54.1 0.1 2.7 2 1 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 CBZ30766.1 - 1.5e-07 31.2 0.0 3.8e-06 26.6 0.0 2.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase HTH_8 PF02954.19 CBZ30766.1 - 0.0029 17.4 0.0 0.027 14.2 0.1 2.3 2 0 0 2 2 2 1 Bacterial regulatory protein, Fis family A_deaminase PF00962.22 CBZ30767.1 - 6e-58 196.7 0.0 7.7e-58 196.4 0.0 1.1 1 0 0 1 1 1 1 Adenosine/AMP deaminase adh_short PF00106.25 CBZ30768.1 - 2.1e-14 53.4 0.3 6.8e-14 51.8 0.1 1.9 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 CBZ30768.1 - 8.6e-09 35.3 0.6 7.8e-08 32.1 0.2 2.5 2 1 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CBZ30768.1 - 0.00057 19.8 0.6 0.0031 17.4 0.6 2.0 2 0 0 2 2 2 1 KR domain 3HCDH_N PF02737.18 CBZ30768.1 - 0.0063 16.4 0.1 0.011 15.7 0.1 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain THF_DHG_CYH_C PF02882.19 CBZ30768.1 - 0.023 14.0 0.0 0.05 12.9 0.0 1.6 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain PMT_2 PF13231.6 CBZ30768.1 - 0.026 14.7 1.3 0.049 13.9 1.3 1.4 1 0 0 1 1 1 0 Dolichyl-phosphate-mannose-protein mannosyltransferase NmrA PF05368.13 CBZ30768.1 - 0.12 11.9 0.5 0.29 10.7 0.2 1.7 2 0 0 2 2 2 0 NmrA-like family Ribosomal_L11_N PF03946.14 CBZ30770.1 - 1.1e-16 60.4 0.5 1.8e-16 59.7 0.5 1.4 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.19 CBZ30770.1 - 7.5e-14 52.0 1.8 8.2e-14 51.9 0.6 1.7 2 0 0 2 2 2 1 Ribosomal protein L11, RNA binding domain RRM_1 PF00076.22 CBZ30771.1 - 7.6e-36 121.8 0.0 4.9e-17 61.5 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_Rrp7 PF17799.1 CBZ30771.1 - 4.4e-05 23.3 0.0 0.17 11.7 0.0 2.2 2 0 0 2 2 2 2 Rrp7 RRM-like N-terminal domain RRM_7 PF16367.5 CBZ30771.1 - 0.0046 17.1 0.0 0.16 12.1 0.0 2.2 2 0 0 2 2 2 1 RNA recognition motif KMP11 PF03037.16 CBZ30772.1 - 1e-55 186.4 17.8 1.2e-55 186.3 17.8 1.0 1 0 0 1 1 1 1 Kinetoplastid membrane protein 11 Apolipoprotein PF01442.18 CBZ30772.1 - 0.0023 17.8 3.5 0.0059 16.5 3.5 1.6 1 1 0 1 1 1 1 Apolipoprotein A1/A4/E domain Lyase_8_N PF08124.11 CBZ30772.1 - 0.052 12.5 1.6 0.053 12.4 1.6 1.1 1 0 0 1 1 1 0 Polysaccharide lyase family 8, N terminal alpha-helical domain TetR_C_15 PF17918.1 CBZ30772.1 - 0.092 13.5 1.5 12 6.7 0.1 2.1 1 1 1 2 2 2 0 Tetracyclin repressor-like, C-terminal domain PIN_8 PF18476.1 CBZ30772.1 - 0.11 12.3 6.2 0.12 12.2 6.2 1.0 1 0 0 1 1 1 0 PIN like domain YtxH PF12732.7 CBZ30772.1 - 0.15 12.6 1.6 0.74 10.4 1.6 1.9 1 1 0 1 1 1 0 YtxH-like protein ZnuA PF01297.17 CBZ30772.1 - 0.16 11.4 3.5 1.7 8.0 0.2 2.0 1 1 1 2 2 2 0 Zinc-uptake complex component A periplasmic DUF3987 PF13148.6 CBZ30772.1 - 0.25 10.3 4.4 0.16 10.9 2.8 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF3987) TipAS PF07739.13 CBZ30772.1 - 0.3 11.7 9.5 0.59 10.7 3.2 2.0 1 1 1 2 2 2 0 TipAS antibiotic-recognition domain baeRF_family5 PF18846.1 CBZ30772.1 - 0.76 10.0 8.2 0.34 11.1 4.0 1.9 1 1 1 2 2 2 0 Bacterial archaeo-eukaryotic release factor family 5 DUF2935 PF11155.8 CBZ30772.1 - 1.4 9.3 9.9 0.44 10.9 5.4 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF2935) OmpH PF03938.14 CBZ30772.1 - 6.8 7.0 12.5 19 5.6 12.5 1.7 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) KMP11 PF03037.16 CBZ30773.1 - 1.6e-56 189.0 17.4 1.8e-56 188.9 17.4 1.0 1 0 0 1 1 1 1 Kinetoplastid membrane protein 11 Apolipoprotein PF01442.18 CBZ30773.1 - 0.0069 16.3 3.6 0.018 14.9 3.6 1.6 1 1 0 1 1 1 1 Apolipoprotein A1/A4/E domain Lyase_8_N PF08124.11 CBZ30773.1 - 0.047 12.6 1.4 0.048 12.6 1.4 1.1 1 0 0 1 1 1 0 Polysaccharide lyase family 8, N terminal alpha-helical domain TetR_C_15 PF17918.1 CBZ30773.1 - 0.13 13.0 1.1 10 6.9 0.1 2.1 1 1 1 2 2 2 0 Tetracyclin repressor-like, C-terminal domain TipAS PF07739.13 CBZ30773.1 - 0.32 11.5 9.6 0.62 10.6 3.4 2.1 1 1 1 2 2 2 0 TipAS antibiotic-recognition domain YtxH PF12732.7 CBZ30773.1 - 0.36 11.4 2.6 1.8 9.2 2.6 1.9 1 1 0 1 1 1 0 YtxH-like protein ZnuA PF01297.17 CBZ30773.1 - 0.4 10.0 4.2 3.9 6.8 4.2 1.9 1 1 0 1 1 1 0 Zinc-uptake complex component A periplasmic DUF4446 PF14584.6 CBZ30773.1 - 0.65 10.0 3.9 0.73 9.8 3.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) baeRF_family5 PF18846.1 CBZ30773.1 - 0.77 10.0 8.3 0.52 10.5 4.6 1.9 1 1 1 2 2 2 0 Bacterial archaeo-eukaryotic release factor family 5 Amidase PF01425.21 CBZ30773.1 - 1 8.3 2.5 1.1 8.2 2.5 1.0 1 0 0 1 1 1 0 Amidase Vps54 PF07928.12 CBZ30773.1 - 1.3 9.5 4.0 1.2 9.6 1.6 1.8 2 0 0 2 2 2 0 Vps54-like protein DUF2884 PF11101.8 CBZ30773.1 - 3.5 7.1 8.4 3.2 7.2 0.4 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF2884) OmpH PF03938.14 CBZ30773.1 - 7 7.0 12.7 18 5.7 12.7 1.6 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) KMP11 PF03037.16 CBZ30774.1 - 1.3e-57 192.5 17.0 1.4e-57 192.4 17.0 1.0 1 0 0 1 1 1 1 Kinetoplastid membrane protein 11 Apolipoprotein PF01442.18 CBZ30774.1 - 0.0018 18.2 2.8 0.0048 16.8 2.8 1.6 1 1 0 1 1 1 1 Apolipoprotein A1/A4/E domain Lyase_8_N PF08124.11 CBZ30774.1 - 0.037 13.0 1.2 0.038 12.9 1.2 1.1 1 0 0 1 1 1 0 Polysaccharide lyase family 8, N terminal alpha-helical domain TetR_C_15 PF17918.1 CBZ30774.1 - 0.097 13.4 1.6 10 6.9 0.1 2.1 1 1 1 2 2 2 0 Tetracyclin repressor-like, C-terminal domain DUF3987 PF13148.6 CBZ30774.1 - 0.11 11.4 2.8 0.14 11.1 2.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) YtxH PF12732.7 CBZ30774.1 - 0.14 12.7 1.5 0.68 10.5 1.5 1.9 1 1 0 1 1 1 0 YtxH-like protein ZnuA PF01297.17 CBZ30774.1 - 0.19 11.1 4.0 1.7 8.0 0.2 2.0 1 1 1 2 2 2 0 Zinc-uptake complex component A periplasmic TipAS PF07739.13 CBZ30774.1 - 0.38 11.3 9.4 0.74 10.4 3.0 2.0 1 1 1 2 2 2 0 TipAS antibiotic-recognition domain baeRF_family5 PF18846.1 CBZ30774.1 - 1.3 9.2 7.5 0.84 9.8 3.1 1.9 1 1 1 2 2 2 0 Bacterial archaeo-eukaryotic release factor family 5 Vps54 PF07928.12 CBZ30774.1 - 1.7 9.1 4.3 1.5 9.3 1.8 1.8 2 0 0 2 2 2 0 Vps54-like protein DUF2884 PF11101.8 CBZ30774.1 - 2 7.9 8.6 3.3 7.2 0.5 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2884) OmpH PF03938.14 CBZ30774.1 - 5.8 7.3 12.0 15 5.9 12.0 1.6 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) ATG_C PF09333.11 CBZ30777.1 - 0.0014 18.9 0.1 0.042 14.2 0.1 2.8 1 1 0 1 1 1 1 Autophagy-related protein C terminal domain ATP-grasp_4 PF13535.6 CBZ30778.1 - 8.6e-07 28.7 0.0 5.8e-06 26.0 0.0 2.0 1 1 0 1 1 1 1 ATP-grasp domain LAL_C2 PF18603.1 CBZ30778.1 - 9.9e-06 25.6 0.3 3.5e-05 23.9 0.0 2.1 2 0 0 2 2 2 1 L-amino acid ligase C-terminal domain 2 ATPgrasp_Ter PF15632.6 CBZ30778.1 - 0.00014 21.6 0.1 0.11 12.3 0.0 2.4 2 0 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon CPSase_L_D2 PF02786.17 CBZ30778.1 - 0.035 13.6 0.0 4.9 6.6 0.0 2.2 2 0 0 2 2 2 0 Carbamoyl-phosphate synthase L chain, ATP binding domain ATP-grasp_3 PF02655.14 CBZ30778.1 - 0.05 13.7 0.0 0.29 11.2 0.0 2.3 1 1 0 1 1 1 0 ATP-grasp domain Helicase_C PF00271.31 CBZ30779.1 - 9.8e-09 35.5 0.0 2.5e-08 34.2 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 CBZ30779.1 - 0.00011 22.1 0.0 0.00027 20.7 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 CBZ30779.1 - 0.033 14.4 0.1 0.26 11.6 0.0 2.5 3 0 0 3 3 3 0 AAA domain DFRP_C PF16543.5 CBZ30782.1 - 0.072 13.6 0.2 0.29 11.6 0.1 2.0 2 0 0 2 2 2 0 DRG Family Regulatory Proteins, Tma46 DFF-C PF09033.10 CBZ30783.1 - 0.038 13.9 0.0 0.071 13.0 0.0 1.4 1 0 0 1 1 1 0 DNA Fragmentation factor 45kDa, C terminal domain Pkinase PF00069.25 CBZ30784.1 - 1.1e-41 143.0 0.1 5.7e-23 81.6 0.0 3.0 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ30784.1 - 1.1e-26 93.7 0.0 1e-22 80.7 0.0 2.3 1 1 1 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 CBZ30784.1 - 0.00025 20.5 0.1 0.063 12.6 0.0 2.2 2 0 0 2 2 2 2 Kinase-like Pox_ser-thr_kin PF05445.11 CBZ30784.1 - 0.28 10.1 0.1 0.42 9.5 0.1 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase HEAT_EZ PF13513.6 CBZ30785.1 - 3.3e-09 37.1 5.1 0.004 17.6 0.1 5.9 6 0 0 6 6 6 2 HEAT-like repeat HEAT PF02985.22 CBZ30785.1 - 0.00026 21.0 4.6 53 4.5 0.1 7.2 6 0 0 6 6 6 0 HEAT repeat TAF6_C PF07571.13 CBZ30785.1 - 0.0073 16.6 0.1 37 4.7 0.0 4.5 4 1 0 4 4 4 0 TAF6 C-terminal HEAT repeat domain 2Fe-2S_thioredx PF01257.19 CBZ30785.1 - 0.014 15.3 0.0 0.032 14.1 0.0 1.6 1 0 0 1 1 1 0 Thioredoxin-like [2Fe-2S] ferredoxin RIX1 PF08167.12 CBZ30785.1 - 0.017 14.9 0.6 9.3 5.9 0.0 3.6 4 1 0 4 4 4 0 rRNA processing/ribosome biogenesis UME PF08064.13 CBZ30785.1 - 0.031 14.2 0.5 2.7 8.0 0.1 3.6 2 1 0 2 2 2 0 UME (NUC010) domain IBN_N PF03810.19 CBZ30785.1 - 0.054 13.4 0.9 0.28 11.1 0.9 2.3 1 0 0 1 1 1 0 Importin-beta N-terminal domain Arm PF00514.23 CBZ30785.1 - 0.076 13.1 3.2 11 6.2 0.1 4.4 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat Adaptin_N PF01602.20 CBZ30785.1 - 0.14 10.7 0.0 0.34 9.4 0.0 1.6 1 0 0 1 1 1 0 Adaptin N terminal region CAF1 PF04857.20 CBZ30786.1 - 3.3e-59 200.7 0.0 4.9e-59 200.1 0.0 1.3 1 0 0 1 1 1 1 CAF1 family ribonuclease PUF PF00806.19 CBZ30786.1 - 0.15 11.8 0.0 0.28 11.0 0.0 1.5 1 0 0 1 1 1 0 Pumilio-family RNA binding repeat Peptidase_M24 PF00557.24 CBZ30787.1 - 3.1e-51 174.0 0.4 4.5e-51 173.5 0.4 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.16 CBZ30787.1 - 7.8e-21 74.1 0.0 1.7e-20 73.0 0.0 1.5 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain DUF3793 PF12672.7 CBZ30787.1 - 0.035 14.2 0.0 0.073 13.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3793) DUF1764 PF08576.10 CBZ30788.1 - 3.6e-08 34.2 4.9 3.5e-07 31.0 1.9 2.5 1 1 2 3 3 3 1 Eukaryotic protein of unknown function (DUF1764) DUF2341 PF10102.9 CBZ30788.1 - 0.13 12.8 0.5 0.45 11.1 0.2 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF2341) SET PF00856.28 CBZ30789.1 - 0.0011 19.4 0.0 0.014 15.8 0.0 2.4 2 1 1 3 3 3 1 SET domain Spt4 PF06093.13 CBZ30791.1 - 1.2e-09 38.1 0.1 1.5e-09 37.8 0.1 1.2 1 0 0 1 1 1 1 Spt4/RpoE2 zinc finger WD40 PF00400.32 CBZ30792.1 - 3.2e-05 24.6 0.4 4.1 8.4 0.0 4.6 5 0 0 5 5 5 1 WD domain, G-beta repeat PQQ_2 PF13360.6 CBZ30792.1 - 8.2e-05 22.3 3.4 0.00011 21.9 0.4 2.7 4 0 0 4 4 4 1 PQQ-like domain ANAPC4_WD40 PF12894.7 CBZ30792.1 - 9.1e-05 22.7 0.0 0.03 14.6 0.0 4.4 3 2 2 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain LRR_6 PF13516.6 CBZ30792.1 - 0.019 15.0 0.1 6.4 7.1 0.0 2.8 2 0 0 2 2 2 0 Leucine Rich repeat Arc_C PF18162.1 CBZ30792.1 - 0.062 13.2 0.0 0.14 12.0 0.0 1.5 1 0 0 1 1 1 0 Arc C-lobe mono-CXXC PF15626.6 CBZ30792.1 - 0.18 12.2 2.9 8.5 6.8 0.9 3.4 2 0 0 2 2 2 0 single CXXC unit UCH PF00443.29 CBZ30793.1 - 4.9e-35 121.3 0.2 1.4e-28 100.1 0.1 2.2 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 CBZ30793.1 - 5.1e-09 36.2 2.9 1.2e-07 31.7 2.1 3.1 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase zf-C2H2_jaz PF12171.8 CBZ30793.1 - 0.16 12.3 0.5 0.35 11.2 0.5 1.6 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding zf_UBZ PF18439.1 CBZ30793.1 - 0.47 10.1 4.7 0.71 9.5 0.3 2.6 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger Vps5 PF09325.10 CBZ30794.1 - 4.5e-17 62.4 3.8 6.6e-17 61.8 3.8 1.1 1 0 0 1 1 1 1 Vps5 C terminal like PX PF00787.24 CBZ30794.1 - 1.8e-16 60.1 0.0 3.8e-16 59.1 0.0 1.6 1 0 0 1 1 1 1 PX domain BAR_3_WASP_bdg PF10456.9 CBZ30794.1 - 0.0032 16.9 0.8 0.02 14.4 0.8 1.9 1 1 0 1 1 1 1 WASP-binding domain of Sorting nexin protein DUF5320 PF17253.2 CBZ30794.1 - 0.046 14.8 1.5 11 7.2 0.3 2.9 2 0 0 2 2 2 0 Family of unknown function (DUF5320) DUF4164 PF13747.6 CBZ30794.1 - 0.058 13.7 3.6 0.69 10.2 0.4 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4164) P4Ha_N PF08336.11 CBZ30794.1 - 0.069 13.2 0.9 0.76 9.8 0.0 2.5 2 1 0 2 2 2 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region G0-G1_switch_2 PF15103.6 CBZ30794.1 - 0.089 13.2 0.1 0.2 12.1 0.1 1.5 1 0 0 1 1 1 0 G0/G1 switch protein 2 DUF5405 PF17399.2 CBZ30794.1 - 0.096 13.0 0.0 0.22 11.8 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF5405) FAA_hydrolase PF01557.18 CBZ30796.1 - 6.9e-39 133.8 0.1 1.5e-37 129.4 0.1 2.0 1 1 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family DUF3490 PF11995.8 CBZ30796.1 - 0.0014 18.5 0.0 0.0035 17.2 0.0 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF3490) HECT PF00632.25 CBZ30797.1 - 2e-79 267.2 0.0 4.3e-79 266.2 0.0 1.5 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) IBR PF01485.21 CBZ30797.1 - 0.29 11.4 5.2 0.84 9.9 5.2 1.8 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain C1_1 PF00130.22 CBZ30797.1 - 0.65 9.9 5.6 2.1 8.3 5.6 1.9 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) DUF3492 PF11997.8 CBZ30798.1 - 0.4 10.4 4.4 0.25 11.1 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3492) Nop53 PF07767.11 CBZ30799.1 - 9.2e-17 61.5 19.4 2e-16 60.4 19.4 1.5 1 0 0 1 1 1 1 Nop53 (60S ribosomal biogenesis) TFIIF_alpha PF05793.12 CBZ30799.1 - 0.026 13.2 18.8 0.036 12.7 18.8 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Med3 PF11593.8 CBZ30799.1 - 0.84 8.8 15.7 1.7 7.7 15.7 1.5 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal DUF4551 PF15087.6 CBZ30799.1 - 1.1 8.1 7.8 1.4 7.6 7.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Ndc1_Nup PF09531.10 CBZ30799.1 - 2.8 6.5 7.3 3.2 6.3 7.3 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup SRP-alpha_N PF04086.13 CBZ30799.1 - 8.7 6.2 20.0 14 5.5 20.0 1.4 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal APG6_N PF17675.1 CBZ30800.1 - 0.1 13.1 0.0 0.1 13.1 0.0 3.2 2 1 0 2 2 2 0 Apg6 coiled-coil region V_ATPase_I PF01496.19 CBZ30800.1 - 0.57 8.0 10.5 0.84 7.5 10.5 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family EcKinase PF02958.20 CBZ30800.1 - 0.77 9.0 6.5 1.4 8.1 6.5 1.4 1 0 0 1 1 1 0 Ecdysteroid kinase TMF_TATA_bd PF12325.8 CBZ30800.1 - 1.9 8.8 29.0 2.4 8.4 13.7 3.3 3 0 0 3 3 3 0 TATA element modulatory factor 1 TATA binding MAD PF05557.13 CBZ30800.1 - 8.9 4.5 25.4 13 4.0 25.4 1.1 1 0 0 1 1 1 0 Mitotic checkpoint protein Cupin_6 PF12852.7 CBZ30801.1 - 0.012 15.4 0.7 0.11 12.3 0.0 2.5 2 0 0 2 2 2 0 Cupin Yos1 PF08571.10 CBZ30802.1 - 7.6e-25 87.0 0.0 1.3e-24 86.3 0.0 1.4 1 1 0 1 1 1 1 Yos1-like DUF4337 PF14235.6 CBZ30802.1 - 2 8.5 3.4 3.4 7.8 0.3 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4337) zf-RING_2 PF13639.6 CBZ30803.1 - 8.2e-08 32.5 19.3 0.00011 22.4 0.2 3.9 3 1 0 3 3 3 2 Ring finger domain zf-RING_11 PF17123.5 CBZ30803.1 - 6.9e-07 28.9 3.2 0.00061 19.5 0.3 4.4 4 1 0 4 4 4 2 RING-like zinc finger zf-RING_UBOX PF13445.6 CBZ30803.1 - 6.5e-06 26.1 20.8 0.018 15.0 0.1 5.3 5 0 0 5 5 5 2 RING-type zinc-finger zf-RING_5 PF14634.6 CBZ30803.1 - 2.6e-05 24.1 8.0 0.00053 19.9 0.1 4.6 5 1 0 5 5 4 2 zinc-RING finger domain IQ PF00612.27 CBZ30803.1 - 9.5e-05 21.9 2.1 0.00039 20.0 2.1 2.2 1 0 0 1 1 1 1 IQ calmodulin-binding motif Prok-RING_4 PF14447.6 CBZ30803.1 - 0.00052 19.8 15.9 1 9.3 0.0 5.3 5 0 0 5 5 5 1 Prokaryotic RING finger family 4 Zf_RING PF16744.5 CBZ30803.1 - 0.0026 17.8 7.4 0.012 15.7 0.1 3.5 3 0 0 3 3 3 1 KIAA1045 RING finger MoaE PF02391.17 CBZ30803.1 - 0.018 15.3 0.3 0.053 13.8 0.3 1.8 1 0 0 1 1 1 0 MoaE protein zf-C3HC4 PF00097.25 CBZ30803.1 - 0.018 14.9 17.1 0.39 10.6 1.2 4.7 4 1 0 4 4 4 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 CBZ30803.1 - 0.099 12.5 0.1 0.099 12.5 0.1 5.3 5 0 0 5 5 5 0 Zinc finger, C3HC4 type (RING finger) Eapp_C PF10238.9 CBZ30803.1 - 0.12 12.4 5.1 23 5.1 0.1 3.6 3 1 1 4 4 4 0 E2F-associated phosphoprotein Zn_ribbon_17 PF17120.5 CBZ30803.1 - 0.57 9.8 11.2 0.83 9.3 0.1 3.5 3 0 0 3 3 3 0 Zinc-ribbon, C4HC2 type zf-rbx1 PF12678.7 CBZ30803.1 - 1.5 9.2 26.0 2.5 8.5 5.1 4.6 3 2 0 3 3 3 0 RING-H2 zinc finger domain zf-C3HC4_3 PF13920.6 CBZ30803.1 - 9 6.2 25.4 0.4 10.6 4.0 5.1 3 2 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) CS PF04969.16 CBZ30804.1 - 0.18 12.8 0.3 0.46 11.5 0.3 1.6 2 0 0 2 2 2 0 CS domain SUR7 PF06687.12 CBZ30805.1 - 1.7 8.2 14.3 0.18 11.4 8.9 1.9 1 1 1 2 2 2 0 SUR7/PalI family RRM_1 PF00076.22 CBZ30806.1 - 1.6e-25 88.7 0.1 1.5e-14 53.6 0.0 3.6 2 1 1 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CBZ30806.1 - 7.6e-08 32.4 0.0 0.012 15.7 0.0 2.7 2 0 0 2 2 2 2 RNA recognition motif RRM_Rrp7 PF17799.1 CBZ30806.1 - 0.009 15.8 0.0 4.7 7.0 0.0 2.3 2 0 0 2 2 2 2 Rrp7 RRM-like N-terminal domain RRM_occluded PF16842.5 CBZ30806.1 - 0.13 12.1 0.0 9.4 6.2 0.0 3.2 3 1 0 3 3 3 0 Occluded RNA-recognition motif FAD_binding_1 PF00667.20 CBZ30807.1 - 1.3e-29 103.4 0.0 2.1e-29 102.7 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.25 CBZ30807.1 - 1.9e-16 60.5 0.4 1.2e-11 45.0 0.0 3.0 3 0 0 3 3 3 2 Flavodoxin FAD_binding_6 PF00970.24 CBZ30807.1 - 0.0002 21.6 0.0 0.0014 19.0 0.0 2.1 2 0 0 2 2 2 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.21 CBZ30807.1 - 0.02 15.5 0.1 0.74 10.5 0.1 2.5 1 1 0 1 1 1 0 Oxidoreductase NAD-binding domain Acetyltransf_16 PF05301.11 CBZ30808.1 - 0.2 11.4 0.0 0.28 10.9 0.0 1.2 1 0 0 1 1 1 0 GNAT acetyltransferase, Mec-17 FixS PF03597.15 CBZ30809.1 - 0.03 14.0 0.3 0.055 13.2 0.3 1.4 1 0 0 1 1 1 0 Cytochrome oxidase maturation protein cbb3-type DHHC PF01529.20 CBZ30810.1 - 1.1e-25 90.3 9.4 1.1e-25 90.3 9.4 2.1 2 1 0 2 2 2 1 DHHC palmitoyltransferase YwiC PF14256.6 CBZ30810.1 - 0.012 15.9 0.5 0.012 15.9 0.5 2.2 2 1 0 2 2 2 0 YwiC-like protein DUF1772 PF08592.11 CBZ30810.1 - 0.033 14.5 6.9 0.12 12.7 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1772) Transgly_assoc PF04226.13 CBZ30810.1 - 0.72 10.1 8.0 0.71 10.2 0.7 2.5 2 0 0 2 2 2 0 Transglycosylase associated protein GREB1 PF15782.5 CBZ30811.1 - 2 5.4 10.3 2.2 5.3 10.3 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer NIF PF03031.18 CBZ30812.1 - 1e-27 96.8 0.1 2e-27 95.9 0.1 1.4 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase CAP_N PF01213.19 CBZ30812.1 - 4.7 6.6 6.4 3.1 7.2 0.7 2.2 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal zf-HC5HC2H PF13771.6 CBZ30813.1 - 6e-06 26.4 8.5 6e-06 26.4 8.5 2.3 2 0 0 2 2 2 1 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.6 CBZ30813.1 - 7.4e-05 22.9 9.4 7.4e-05 22.9 9.4 2.5 2 1 0 2 2 2 1 PHD-zinc-finger like domain TruD PF01142.18 CBZ30814.1 - 6.1e-05 22.0 0.1 0.16 10.8 0.0 2.2 2 0 0 2 2 2 2 tRNA pseudouridine synthase D (TruD) HCMVantigenic_N PF12154.8 CBZ30816.1 - 0.21 11.7 2.5 16 5.7 0.0 3.1 2 0 0 2 2 2 0 Glycoprotein B N-terminal antigenic domain of HCMV Ank_4 PF13637.6 CBZ30817.1 - 3.8e-24 84.7 6.0 4.5e-10 39.8 0.0 3.5 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_2 PF12796.7 CBZ30817.1 - 7.5e-22 77.7 0.6 8.4e-15 55.1 0.3 2.3 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 CBZ30817.1 - 6.8e-20 70.6 2.5 1.6e-10 40.9 0.0 3.8 4 0 0 4 4 4 3 Ankyrin repeat Ank_3 PF13606.6 CBZ30817.1 - 2.7e-19 67.2 0.6 2.4e-06 27.4 0.0 3.9 5 0 0 5 5 5 3 Ankyrin repeat Ank_5 PF13857.6 CBZ30817.1 - 1.3e-15 57.3 2.7 4.7e-09 36.3 0.1 3.7 2 1 2 4 4 4 2 Ankyrin repeats (many copies) HSBP1 PF06825.12 CBZ30818.1 - 6e-23 80.4 5.7 7e-23 80.2 5.7 1.1 1 0 0 1 1 1 1 Heat shock factor binding protein 1 DUF4618 PF15397.6 CBZ30818.1 - 0.0017 17.8 0.2 0.0019 17.6 0.2 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4618) BLOC1_2 PF10046.9 CBZ30818.1 - 0.0049 17.1 0.2 0.0063 16.8 0.2 1.1 1 0 0 1 1 1 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 BORCS6 PF10157.9 CBZ30818.1 - 0.0057 16.9 0.1 0.0072 16.6 0.1 1.1 1 0 0 1 1 1 1 BLOC-1-related complex sub-unit 6 UPF0184 PF03670.13 CBZ30818.1 - 0.0093 16.3 0.1 0.012 16.0 0.1 1.2 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0184) DUF4113 PF13438.6 CBZ30818.1 - 0.011 15.8 0.1 0.055 13.6 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4113) FtsK_SpoIIIE PF01580.18 CBZ30818.1 - 0.014 14.7 0.1 0.014 14.7 0.1 1.0 1 0 0 1 1 1 0 FtsK/SpoIIIE family Apolipoprotein PF01442.18 CBZ30818.1 - 0.015 15.2 0.2 0.018 14.9 0.2 1.1 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain YvrJ PF12841.7 CBZ30818.1 - 0.018 14.6 0.2 0.061 12.9 0.2 1.8 2 0 0 2 2 2 0 YvrJ protein family Baculo_PEP_C PF04513.12 CBZ30818.1 - 0.018 15.1 0.0 0.021 14.9 0.0 1.1 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus CLZ PF16526.5 CBZ30818.1 - 0.019 15.3 0.6 0.033 14.5 0.4 1.5 1 1 1 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Fzo_mitofusin PF04799.13 CBZ30818.1 - 0.028 14.0 0.3 0.032 13.8 0.3 1.1 1 0 0 1 1 1 0 fzo-like conserved region Not3 PF04065.15 CBZ30818.1 - 0.028 13.8 0.3 0.03 13.8 0.3 1.1 1 0 0 1 1 1 0 Not1 N-terminal domain, CCR4-Not complex component MtrB PF05440.12 CBZ30818.1 - 0.038 14.4 0.0 0.046 14.1 0.0 1.2 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase subunit B DUF948 PF06103.11 CBZ30818.1 - 0.051 13.8 0.5 3.4 8.0 0.1 2.0 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) IL11 PF07400.11 CBZ30818.1 - 0.057 13.1 0.2 0.15 11.7 0.2 1.7 1 1 0 1 1 1 0 Interleukin 11 DUF4407 PF14362.6 CBZ30818.1 - 0.069 12.5 0.1 0.078 12.3 0.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Nsp1_C PF05064.13 CBZ30818.1 - 0.071 12.9 0.6 0.081 12.7 0.6 1.1 1 0 0 1 1 1 0 Nsp1-like C-terminal region Trimer_CC PF08954.11 CBZ30818.1 - 0.074 12.6 0.9 0.22 11.1 0.6 1.8 1 1 1 2 2 2 0 Trimerisation motif Mt_ATP-synt_D PF05873.12 CBZ30818.1 - 0.11 12.3 0.0 0.12 12.2 0.0 1.1 1 0 0 1 1 1 0 ATP synthase D chain, mitochondrial (ATP5H) DUF2730 PF10805.8 CBZ30818.1 - 0.12 12.4 0.2 0.23 11.5 0.2 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2730) HSCB_C PF07743.13 CBZ30818.1 - 0.43 11.1 3.6 1.2 9.7 3.6 1.7 1 1 0 1 1 1 0 HSCB C-terminal oligomerisation domain BTB_2 PF02214.22 CBZ30819.1 - 3.9e-11 43.2 0.0 1e-10 41.8 0.0 1.7 2 0 0 2 2 2 1 BTB/POZ domain Atg14 PF10186.9 CBZ30819.1 - 0.04 13.0 0.2 0.058 12.5 0.2 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF3181 PF11378.8 CBZ30819.1 - 0.076 13.3 0.0 0.14 12.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3181) TRAPPC9-Trs120 PF08626.11 CBZ30820.1 - 5.8e-05 20.7 0.0 0.00085 16.8 0.0 2.4 3 0 0 3 3 3 2 Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit PLD_C PF12357.8 CBZ30820.1 - 0.13 12.2 0.0 0.28 11.1 0.0 1.5 1 0 0 1 1 1 0 Phospholipase D C terminal SNARE PF05739.19 CBZ30822.1 - 5.3e-12 45.5 0.2 1.4e-11 44.1 0.2 1.8 1 0 0 1 1 1 1 SNARE domain Syntaxin PF00804.25 CBZ30822.1 - 8.6e-05 22.3 17.3 0.00013 21.7 17.3 1.3 1 0 0 1 1 1 1 Syntaxin Lipoprotein_6 PF01441.19 CBZ30822.1 - 0.15 12.1 2.1 0.99 9.4 0.3 2.2 2 0 0 2 2 2 0 Lipoprotein Syntaxin-5_N PF11416.8 CBZ30822.1 - 0.17 11.2 0.5 0.42 9.9 0.5 1.6 1 0 0 1 1 1 0 Syntaxin-5 N-terminal, Sly1p-binding domain PBECR5 PF18814.1 CBZ30822.1 - 3.5 7.5 12.5 0.35 10.8 6.0 2.0 2 0 0 2 2 2 0 phage-Barnase-EndoU-ColicinE5/D-RelE like nuclease5 Acyl-CoA_dh_1 PF00441.24 CBZ30824.1 - 2.9e-40 137.9 2.7 4e-40 137.5 2.7 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 CBZ30824.1 - 4.3e-27 94.2 0.3 1.8e-26 92.2 0.1 2.1 3 0 0 3 3 3 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 CBZ30824.1 - 7e-25 87.9 0.0 1.7e-24 86.6 0.0 1.7 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 CBZ30824.1 - 8.1e-20 71.5 0.1 1.2e-19 70.9 0.1 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain GalKase_gal_bdg PF10509.9 CBZ30825.1 - 3.8e-14 52.0 0.1 1.6e-13 50.0 0.0 2.1 2 0 0 2 2 2 1 Galactokinase galactose-binding signature GHMP_kinases_C PF08544.13 CBZ30825.1 - 6.1e-08 32.9 0.0 2.5e-07 31.0 0.0 2.1 1 0 0 1 1 1 1 GHMP kinases C terminal GHMP_kinases_N PF00288.26 CBZ30825.1 - 8.2e-07 29.2 0.2 1.6e-06 28.2 0.2 1.5 1 0 0 1 1 1 1 GHMP kinases N terminal domain MMR_HSR1 PF01926.23 CBZ30827.1 - 2.6e-06 27.5 0.0 5.3e-06 26.5 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 CBZ30827.1 - 0.0022 17.5 0.0 0.0071 15.9 0.0 1.8 1 1 0 1 1 1 1 Ferrous iron transport protein B AAA_16 PF13191.6 CBZ30827.1 - 0.0054 17.1 0.6 0.019 15.4 0.0 2.2 2 2 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 CBZ30827.1 - 0.087 13.1 0.1 3.6 7.9 0.0 2.5 1 1 0 2 2 2 0 AAA domain Septin PF00735.18 CBZ30827.1 - 0.19 11.0 0.0 7.6 5.7 0.1 2.7 3 0 0 3 3 3 0 Septin IQ PF00612.27 CBZ30828.1 - 0.00088 18.9 2.2 0.0028 17.3 2.2 1.9 1 0 0 1 1 1 1 IQ calmodulin-binding motif MFS_1 PF07690.16 CBZ30829.1 - 1.4e-27 96.6 38.9 1.4e-21 76.8 16.5 2.2 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 CBZ30829.1 - 5.1e-12 45.4 8.5 5.1e-12 45.4 8.5 2.2 2 0 0 2 2 2 1 Sugar (and other) transporter MFS_4 PF06779.14 CBZ30829.1 - 0.0027 17.1 11.6 0.0036 16.6 6.1 2.9 2 1 1 3 3 3 2 Uncharacterised MFS-type transporter YbfB DUF5075 PF16825.5 CBZ30830.1 - 0.0004 20.1 0.4 0.00056 19.7 0.4 1.2 1 0 0 1 1 1 1 IGP family C-type lectin domain Hum_adeno_E3A PF05393.11 CBZ30830.1 - 0.056 13.4 0.2 0.11 12.5 0.2 1.4 1 0 0 1 1 1 0 Human adenovirus early E3A glycoprotein DUF4492 PF14899.6 CBZ30830.1 - 0.064 13.2 0.3 0.11 12.4 0.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4492) ATP-synt_8 PF00895.20 CBZ30830.1 - 0.08 13.4 1.8 0.23 11.9 1.8 1.7 1 0 0 1 1 1 0 ATP synthase protein 8 SCIMP PF15050.6 CBZ30830.1 - 0.11 13.0 0.6 0.18 12.3 0.6 1.4 1 0 0 1 1 1 0 SCIMP protein RCR PF12273.8 CBZ30830.1 - 3.5 8.3 5.8 22 5.7 1.6 2.7 2 1 0 2 2 2 0 Chitin synthesis regulation, resistance to Congo red Abhydrolase_1 PF00561.20 CBZ30831.1 - 6.2e-06 26.1 0.0 8.7e-06 25.6 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF818 PF05677.12 CBZ30831.1 - 9.9e-06 24.7 0.0 1.3e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 Chlamydia CHLPS protein (DUF818) Hydrolase_4 PF12146.8 CBZ30831.1 - 3.8e-05 23.1 0.0 7e-05 22.2 0.0 1.5 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 CBZ30831.1 - 0.0015 18.1 0.0 0.0028 17.1 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_6 PF12697.7 CBZ30831.1 - 0.015 15.9 1.2 0.062 13.9 0.1 2.1 1 1 1 2 2 2 0 Alpha/beta hydrolase family UPF0227 PF05728.12 CBZ30831.1 - 0.036 14.0 0.0 0.071 13.1 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) Abhydrolase_3 PF07859.13 CBZ30831.1 - 0.042 13.7 0.0 0.08 12.8 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold MFS_1 PF07690.16 CBZ30832.1 - 4e-25 88.5 30.8 4.9e-19 68.5 17.1 2.4 2 1 0 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 CBZ30832.1 - 9.8e-08 31.2 15.2 2.5e-05 23.3 3.6 3.2 2 2 1 3 3 3 2 MFS_1 like family MFS_1 PF07690.16 CBZ30833.1 - 5.9e-23 81.4 37.0 2.1e-18 66.4 10.6 2.3 2 1 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 CBZ30833.1 - 2.5e-05 23.3 5.5 2.5e-05 23.3 5.5 2.3 2 1 0 2 2 2 1 Sugar (and other) transporter Cupin_2 PF07883.11 CBZ30834.1 - 0.13 12.0 0.1 0.35 10.6 0.1 1.7 1 0 0 1 1 1 0 Cupin domain Aminotran_5 PF00266.19 CBZ30835.1 - 4e-48 164.2 0.1 1e-28 100.4 0.0 2.2 1 1 1 2 2 2 2 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 CBZ30835.1 - 0.019 14.3 0.1 0.036 13.4 0.1 1.4 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family Beta_elim_lyase PF01212.21 CBZ30835.1 - 0.022 14.0 0.0 0.055 12.7 0.0 1.6 1 1 0 1 1 1 0 Beta-eliminating lyase Leo1 PF04004.13 CBZ30836.1 - 3.4e-10 40.0 6.7 2.1e-09 37.4 6.8 2.1 1 1 0 1 1 1 1 Leo1-like protein DUF4407 PF14362.6 CBZ30836.1 - 9 5.6 13.1 0.84 8.9 8.2 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Alb1 PF09135.11 CBZ30837.1 - 9.8e-05 23.2 7.3 9.8e-05 23.2 7.3 2.2 1 1 1 2 2 2 1 Alb1 DUF4407 PF14362.6 CBZ30837.1 - 1.9 7.7 9.7 2.6 7.3 9.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Agouti PF05039.12 CBZ30837.1 - 2.2 9.1 11.1 6.8 7.5 0.5 2.3 2 0 0 2 2 2 0 Agouti protein Pkinase PF00069.25 CBZ30838.1 - 6.4e-07 29.0 0.0 0.0007 19.0 0.0 2.7 3 0 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ30838.1 - 3.2e-06 26.6 0.0 0.00017 20.9 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase CHAD PF05235.14 CBZ30838.1 - 0.11 12.4 1.2 0.33 10.9 0.2 2.1 2 0 0 2 2 2 0 CHAD domain Sybindin PF04099.12 CBZ30839.1 - 9.3e-18 64.5 0.1 1.1e-17 64.3 0.1 1.0 1 0 0 1 1 1 1 Sybindin-like family CHU_C PF13585.6 CBZ30839.1 - 0.033 14.2 0.1 0.057 13.5 0.1 1.5 1 0 0 1 1 1 0 C-terminal domain of CHU protein family SpoU_methylase PF00588.19 CBZ30840.1 - 2.8e-08 34.0 0.1 2.2e-07 31.2 0.0 2.3 2 0 0 2 2 2 1 SpoU rRNA Methylase family NAGidase PF07555.13 CBZ30840.1 - 0.098 12.0 0.0 0.16 11.3 0.0 1.2 1 0 0 1 1 1 0 beta-N-acetylglucosaminidase PLRV_ORF5 PF01690.17 CBZ30840.1 - 0.11 11.2 0.0 0.21 10.3 0.0 1.4 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein OrfB_IS605 PF01385.19 CBZ30840.1 - 0.27 11.5 3.3 1.8 8.8 0.6 2.6 2 0 0 2 2 2 0 Probable transposase zf-MIZ PF02891.20 CBZ30841.1 - 0.27 11.0 2.3 0.82 9.5 1.9 2.0 2 0 0 2 2 2 0 MIZ/SP-RING zinc finger Tctex-1 PF03645.13 CBZ30842.1 - 3.8e-27 94.5 0.1 4.4e-27 94.3 0.1 1.0 1 0 0 1 1 1 1 Tctex-1 family DSPc PF00782.20 CBZ30842.1 - 0.031 14.1 0.0 0.041 13.7 0.0 1.2 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain DUF4200 PF13863.6 CBZ30843.1 - 0.021 15.2 5.2 0.05 14.0 5.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) FAM184 PF15665.5 CBZ30843.1 - 0.53 10.0 8.5 1.3 8.8 8.5 1.6 1 0 0 1 1 1 0 Family with sequence similarity 184, A and B APG6_N PF17675.1 CBZ30843.1 - 0.69 10.4 7.7 1.8 9.1 7.7 1.7 1 0 0 1 1 1 0 Apg6 coiled-coil region Uso1_p115_C PF04871.13 CBZ30843.1 - 1.2 9.5 5.3 3.2 8.1 5.3 1.7 1 0 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region AgrB PF04647.15 CBZ30844.1 - 0.08 12.2 9.3 0.028 13.7 4.3 2.7 2 0 0 2 2 2 0 Accessory gene regulator B Cupin_8 PF13621.6 CBZ30845.1 - 1.1e-44 153.1 0.1 6.5e-44 150.5 0.0 1.9 2 0 0 2 2 2 1 Cupin-like domain LCM PF04072.14 CBZ30845.1 - 1.4e-15 57.7 0.0 3.4e-09 36.9 0.0 3.0 2 1 0 2 2 2 2 Leucine carboxyl methyltransferase Kelch_5 PF13854.6 CBZ30845.1 - 6.4e-09 35.6 0.0 0.15 12.1 0.0 5.4 5 0 0 5 5 5 2 Kelch motif Kelch_3 PF13415.6 CBZ30845.1 - 2.5e-06 27.6 8.6 0.049 13.9 0.1 5.5 5 0 0 5 5 5 2 Galactose oxidase, central domain Kelch_4 PF13418.6 CBZ30845.1 - 1.2e-05 25.3 1.0 3.2 7.8 0.0 5.9 6 0 0 6 6 6 2 Galactose oxidase, central domain Cupin_4 PF08007.12 CBZ30845.1 - 0.0017 17.9 0.0 0.0032 17.0 0.0 1.4 1 0 0 1 1 1 1 Cupin superfamily protein Kelch_6 PF13964.6 CBZ30845.1 - 0.013 15.8 4.8 80 3.7 0.1 6.2 5 1 1 6 6 6 0 Kelch motif PPR PF01535.20 CBZ30846.1 - 5.6e-23 79.5 22.7 0.039 14.2 0.0 12.0 13 0 0 13 13 13 6 PPR repeat PPR_2 PF13041.6 CBZ30846.1 - 8.8e-22 77.1 11.0 1.7e-06 28.1 0.0 8.9 5 2 3 9 9 9 6 PPR repeat family PPR_3 PF13812.6 CBZ30846.1 - 4.3e-12 45.9 10.6 0.033 14.3 0.1 7.7 5 1 2 8 8 8 6 Pentatricopeptide repeat domain PPR_1 PF12854.7 CBZ30846.1 - 2.6e-10 39.8 0.0 0.44 10.3 0.0 6.2 5 0 0 5 5 5 3 PPR repeat PPR_long PF17177.4 CBZ30846.1 - 4.5e-07 29.4 13.1 4.6e-05 22.9 0.9 5.4 3 2 3 6 6 6 2 Pentacotripeptide-repeat region of PRORP TPR_19 PF14559.6 CBZ30846.1 - 0.082 13.4 1.6 25 5.5 0.0 4.3 4 1 0 4 4 4 0 Tetratricopeptide repeat SPOB_a PF14689.6 CBZ30846.1 - 0.53 10.0 4.8 55 3.6 0.1 4.9 6 0 0 6 6 6 0 Sensor_kinase_SpoOB-type, alpha-helical domain DENN PF02141.21 CBZ30847.1 - 6.8e-24 84.8 0.5 1.2e-23 84.0 0.5 1.3 1 0 0 1 1 1 1 DENN (AEX-3) domain TPR_14 PF13428.6 CBZ30848.1 - 0.0067 17.2 4.7 0.2 12.5 0.3 3.7 1 1 2 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.17 CBZ30848.1 - 0.019 15.1 2.5 2.9 8.2 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_19 PF14559.6 CBZ30848.1 - 0.02 15.4 2.4 0.09 13.3 0.5 2.5 1 1 0 2 2 2 0 Tetratricopeptide repeat Alpha_adaptin_C PF02296.16 CBZ30848.1 - 0.033 14.4 0.0 0.8 9.9 0.0 2.3 2 0 0 2 2 2 0 Alpha adaptin AP2, C-terminal domain TPR_16 PF13432.6 CBZ30848.1 - 0.096 13.3 1.9 5.1 7.8 0.1 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat ANAPC3 PF12895.7 CBZ30848.1 - 0.13 12.5 0.4 0.22 11.8 0.4 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.6 CBZ30848.1 - 0.25 11.7 2.6 6.7 7.2 0.0 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.28 CBZ30848.1 - 0.44 10.5 1.9 18 5.4 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat DnaJ_C PF01556.18 CBZ30849.1 - 9.1e-32 110.2 0.1 1.2e-31 109.8 0.1 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 CBZ30849.1 - 4.8e-21 74.6 1.4 1.1e-20 73.5 1.0 1.8 2 0 0 2 2 2 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 CBZ30849.1 - 7e-15 55.2 20.2 1.5e-14 54.0 20.2 1.6 1 0 0 1 1 1 1 DnaJ central domain Anti-TRAP PF15777.5 CBZ30849.1 - 0.31 11.0 14.5 0.12 12.4 4.0 3.0 1 1 2 3 3 3 0 Tryptophan RNA-binding attenuator protein inhibitory protein HypA PF01155.19 CBZ30849.1 - 0.53 10.3 7.9 4.3 7.4 1.4 2.3 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DNA_pol_A_exo1 PF01612.20 CBZ30850.1 - 2.7e-15 56.5 0.0 4.3e-15 55.9 0.0 1.3 1 0 0 1 1 1 1 3'-5' exonuclease zf-C2H2_10 PF16588.5 CBZ30850.1 - 0.00033 20.3 26.4 0.012 15.4 1.9 3.7 4 0 0 4 4 4 3 C2H2 zinc-finger zf-CCHC PF00098.23 CBZ30850.1 - 0.00033 20.6 32.3 0.0031 17.5 2.4 4.7 4 1 0 4 4 4 3 Zinc knuckle REV1_C PF16727.5 CBZ30850.1 - 0.062 13.7 0.0 0.46 10.9 0.0 2.4 3 0 0 3 3 3 0 DNA repair protein REV1 C-terminal domain zf-C4_ClpX PF06689.13 CBZ30850.1 - 6.6 6.7 11.1 8 6.4 1.7 2.8 2 0 0 2 2 2 0 ClpX C4-type zinc finger Glyoxalase PF00903.25 CBZ30852.1 - 3.6e-14 53.1 0.1 4.6e-14 52.7 0.1 1.2 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 CBZ30852.1 - 8.7e-08 32.4 0.0 1.3e-07 31.8 0.0 1.4 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.7 CBZ30852.1 - 0.0049 16.8 0.1 0.014 15.4 0.1 1.8 1 1 0 1 1 1 1 Glyoxalase-like domain CppA_N PF14506.6 CBZ30852.1 - 0.0068 16.5 0.0 0.0085 16.2 0.0 1.3 1 1 0 1 1 1 1 CppA N-terminal Glyoxalase_3 PF13468.6 CBZ30852.1 - 0.089 12.9 0.0 7.1 6.7 0.0 2.3 2 1 0 2 2 2 0 Glyoxalase-like domain PAF-AH_p_II PF03403.13 CBZ30853.1 - 1.7e-29 102.6 0.0 9.3e-29 100.1 0.0 1.9 1 1 0 1 1 1 1 Platelet-activating factor acetylhydrolase, isoform II Chlorophyllase2 PF12740.7 CBZ30853.1 - 1.5e-06 27.4 0.0 4.6e-06 25.7 0.0 1.7 1 1 0 1 1 1 1 Chlorophyllase enzyme Abhydrolase_6 PF12697.7 CBZ30853.1 - 1.7e-06 28.8 0.0 3.1e-06 27.9 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 CBZ30853.1 - 0.0029 16.9 0.0 2 7.6 0.0 2.4 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 CBZ30853.1 - 0.015 15.0 0.2 0.04 13.6 0.0 1.8 2 0 0 2 2 2 0 alpha/beta hydrolase fold SNARE_assoc PF09335.11 CBZ30853.1 - 0.015 15.8 0.7 0.04 14.4 0.7 1.7 1 0 0 1 1 1 0 SNARE associated Golgi protein Chlorophyllase PF07224.11 CBZ30853.1 - 0.15 11.1 0.0 13 4.6 0.0 2.1 2 0 0 2 2 2 0 Chlorophyllase ICMT PF04140.14 CBZ30854.1 - 1.2e-19 70.5 2.4 1.2e-19 70.5 2.4 1.8 2 0 0 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.13 CBZ30854.1 - 8.9e-07 29.3 2.0 8.9e-07 29.3 2.0 2.8 3 2 1 4 4 4 1 Phospholipid methyltransferase DUF1295 PF06966.12 CBZ30854.1 - 0.0003 20.4 2.6 0.0003 20.4 2.6 2.1 1 1 0 2 2 2 1 Protein of unknown function (DUF1295) DUF2721 PF11026.8 CBZ30854.1 - 0.14 12.1 4.6 0.26 11.2 0.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2721) OST3_OST6 PF04756.13 CBZ30854.1 - 0.15 11.4 1.1 0.15 11.4 0.0 1.5 2 0 0 2 2 2 0 OST3 / OST6 family, transporter family RseC_MucC PF04246.12 CBZ30854.1 - 1.5 8.8 3.6 0.45 10.5 0.2 1.8 2 0 0 2 2 2 0 Positive regulator of sigma(E), RseC/MucC NDUFA12 PF05071.16 CBZ30855.1 - 8.9e-06 26.5 0.7 8.9e-06 26.5 0.7 2.0 2 0 0 2 2 2 1 NADH ubiquinone oxidoreductase subunit NDUFA12 zf-CCHC_2 PF13696.6 CBZ30856.1 - 5.2e-08 32.6 8.2 9.7e-08 31.7 8.2 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-RING_4 PF14570.6 CBZ30856.1 - 0.0083 15.9 1.2 0.0083 15.9 1.2 1.9 2 0 0 2 2 2 1 RING/Ubox like zinc-binding domain zf-RING_14 PF17978.1 CBZ30856.1 - 0.018 15.5 0.4 0.033 14.6 0.4 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-CCHC PF00098.23 CBZ30856.1 - 0.097 12.8 4.5 0.22 11.6 4.5 1.7 1 0 0 1 1 1 0 Zinc knuckle FYVE PF01363.21 CBZ30856.1 - 0.47 10.6 5.3 0.12 12.5 1.0 2.1 2 0 0 2 2 2 0 FYVE zinc finger zf-CCHC_3 PF13917.6 CBZ30856.1 - 1.2 9.1 5.3 1.1 9.2 0.4 2.3 2 0 0 2 2 2 0 Zinc knuckle zf-RING_5 PF14634.6 CBZ30856.1 - 1.6 8.8 9.3 0.97 9.4 3.5 2.4 2 0 0 2 2 2 0 zinc-RING finger domain DZR PF12773.7 CBZ30856.1 - 2 8.5 7.4 2.1 8.4 2.4 2.4 2 0 0 2 2 2 0 Double zinc ribbon TF_Zn_Ribbon PF08271.12 CBZ30856.1 - 4.2 7.0 8.5 1.3 8.6 2.8 2.6 2 1 0 2 2 2 0 TFIIB zinc-binding ThiF PF00899.21 CBZ30857.1 - 3.7e-75 252.4 0.0 1.1e-57 195.2 0.0 2.2 1 1 1 2 2 2 2 ThiF family UBA_e1_thiolCys PF10585.9 CBZ30857.1 - 1.9e-58 198.3 0.1 2.9e-58 197.8 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin-activating enzyme active site E1_4HB PF16191.5 CBZ30857.1 - 3.4e-11 43.2 0.0 8.1e-11 42.0 0.0 1.7 1 0 0 1 1 1 1 Ubiquitin-activating enzyme E1 four-helix bundle 3HCDH_N PF02737.18 CBZ30857.1 - 0.0041 17.0 0.1 0.013 15.4 0.1 1.9 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Rhamno_transf PF11316.8 CBZ30857.1 - 0.085 12.2 0.1 0.17 11.3 0.1 1.4 1 0 0 1 1 1 0 Putative rhamnosyl transferase 2-Hacid_dh_C PF02826.19 CBZ30857.1 - 0.16 11.3 0.3 0.53 9.6 0.1 1.9 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Lipocalin_9 PF17186.4 CBZ30858.1 - 4.5e-07 30.2 0.0 2.6e-06 27.7 0.0 2.2 2 0 0 2 2 2 1 Lipocalin-like domain FGGY_N PF00370.21 CBZ30859.1 - 1.3e-67 228.0 0.0 1.7e-67 227.6 0.0 1.1 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain FGGY_C PF02782.16 CBZ30859.1 - 5.5e-60 202.5 1.1 1.2e-59 201.4 1.1 1.6 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain DnaJ PF00226.31 CBZ30860.1 - 1.4e-09 37.9 0.0 3.3e-09 36.8 0.0 1.6 1 0 0 1 1 1 1 DnaJ domain DEAD PF00270.29 CBZ30861.1 - 9.5e-43 146.0 0.0 1.7e-41 141.9 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CBZ30861.1 - 6.8e-31 106.9 0.1 1.4e-30 105.9 0.1 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 CBZ30861.1 - 0.0004 20.4 0.0 0.00094 19.2 0.0 1.5 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 CBZ30861.1 - 0.015 14.6 0.1 0.026 13.7 0.1 1.3 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase AAA_22 PF13401.6 CBZ30861.1 - 0.052 13.8 0.4 0.46 10.8 0.4 2.4 1 1 0 1 1 1 0 AAA domain Dynein_light PF01221.18 CBZ30864.1 - 4.5e-14 52.5 0.4 6.2e-14 52.1 0.4 1.3 1 1 0 1 1 1 1 Dynein light chain type 1 IPK PF03770.16 CBZ30865.1 - 1.5e-19 70.6 0.0 1.4e-18 67.5 0.0 2.1 1 1 0 1 1 1 1 Inositol polyphosphate kinase Flavokinase PF01687.17 CBZ30867.1 - 3e-25 88.7 0.0 3.6e-25 88.4 0.0 1.1 1 0 0 1 1 1 1 Riboflavin kinase Pkinase PF00069.25 CBZ30868.1 - 8.9e-41 140.0 0.0 1.6e-40 139.2 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ30868.1 - 2.3e-17 63.2 0.0 1.5e-12 47.3 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 CBZ30868.1 - 7.3e-07 28.3 0.0 2.4e-06 26.6 0.0 1.8 2 0 0 2 2 2 1 Fungal protein kinase APH PF01636.23 CBZ30868.1 - 8.8e-05 22.5 0.1 0.00077 19.4 0.1 2.4 1 1 1 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.22 CBZ30868.1 - 0.015 14.9 0.0 0.026 14.1 0.0 1.3 1 0 0 1 1 1 0 RIO1 family DNA_pol_phi PF04931.13 CBZ30869.1 - 2.4 6.1 6.0 3.4 5.6 6.0 1.2 1 0 0 1 1 1 0 DNA polymerase phi His_Phos_1 PF00300.22 CBZ30870.1 - 3.3e-11 43.2 0.0 5.8e-09 35.9 0.0 2.5 2 0 0 2 2 2 2 Histidine phosphatase superfamily (branch 1) RRM_1 PF00076.22 CBZ30871.1 - 1.4e-07 31.2 0.0 5.4e-07 29.3 0.0 1.9 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) EF-hand_13 PF17958.1 CBZ30872.1 - 3.1e-17 62.1 0.0 6.6e-17 61.1 0.0 1.5 1 0 0 1 1 1 1 EF-hand domain EF-hand_7 PF13499.6 CBZ30872.1 - 3e-12 46.8 0.0 2e-11 44.2 0.0 2.5 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.6 CBZ30872.1 - 0.011 15.6 2.5 0.019 14.8 0.1 2.8 3 0 0 3 3 3 0 EF-hand domain EF-hand_1 PF00036.32 CBZ30872.1 - 0.023 14.2 5.4 0.11 12.1 0.2 3.4 3 0 0 3 3 3 0 EF hand EF-hand_8 PF13833.6 CBZ30872.1 - 0.055 13.3 4.9 4.3 7.3 1.1 2.8 2 1 0 2 2 2 0 EF-hand domain pair Popeye PF04831.13 CBZ30872.1 - 0.093 12.9 0.0 0.14 12.3 0.0 1.3 1 0 0 1 1 1 0 Popeye protein conserved region EF-hand_5 PF13202.6 CBZ30872.1 - 0.16 11.5 0.5 0.58 9.8 0.0 2.2 2 0 0 2 2 2 0 EF hand PGM_PMM_II PF02879.16 CBZ30873.1 - 0.05 14.2 0.1 2.5 8.8 0.0 2.4 1 1 1 2 2 2 0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II Cys_Met_Meta_PP PF01053.20 CBZ30874.1 - 5.8e-128 426.7 0.1 6.6e-128 426.5 0.1 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.17 CBZ30874.1 - 4.9e-07 29.4 1.9 1e-06 28.3 0.5 1.8 1 1 1 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.19 CBZ30874.1 - 0.00016 20.7 0.1 0.00031 19.8 0.0 1.4 1 1 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 CBZ30874.1 - 0.00037 19.9 0.6 0.0006 19.2 0.6 1.3 1 1 0 1 1 1 1 Beta-eliminating lyase SepSecS PF05889.13 CBZ30874.1 - 0.073 11.8 0.1 0.11 11.2 0.1 1.2 1 0 0 1 1 1 0 O-phosphoseryl-tRNA(Sec) selenium transferase, SepSecS DUF3586 PF12131.8 CBZ30874.1 - 1.4 9.2 6.1 0.64 10.3 2.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3586) Dehydratase_MU PF02288.15 CBZ30875.1 - 6.5 6.7 14.1 0.071 13.0 1.4 3.6 3 1 0 3 3 3 0 Dehydratase medium subunit AAA PF00004.29 CBZ30876.1 - 3.8e-15 56.5 0.0 7.4e-15 55.5 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rep_fac_C PF08542.11 CBZ30876.1 - 7.8e-12 45.4 0.0 2e-11 44.1 0.0 1.7 1 0 0 1 1 1 1 Replication factor C C-terminal domain Rad17 PF03215.15 CBZ30876.1 - 7.3e-11 42.3 0.0 1.4e-10 41.4 0.0 1.4 1 0 0 1 1 1 1 Rad17 P-loop domain DNA_pol3_delta2 PF13177.6 CBZ30876.1 - 4.2e-10 39.6 0.0 6.1e-09 35.9 0.0 2.2 1 1 0 1 1 1 1 DNA polymerase III, delta subunit AAA_30 PF13604.6 CBZ30876.1 - 6.6e-07 29.2 0.0 3.7e-06 26.8 0.0 1.9 2 0 0 2 2 2 1 AAA domain Mg_chelatase PF01078.21 CBZ30876.1 - 2.8e-06 26.9 0.0 4.6e-06 26.2 0.0 1.3 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_16 PF13191.6 CBZ30876.1 - 5.7e-06 26.8 0.0 4e-05 24.1 0.0 2.2 3 0 0 3 3 2 1 AAA ATPase domain AAA_19 PF13245.6 CBZ30876.1 - 2.3e-05 24.7 0.0 5.2e-05 23.6 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.6 CBZ30876.1 - 2.5e-05 24.5 0.1 0.00015 22.0 0.1 2.3 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.14 CBZ30876.1 - 4.2e-05 23.6 0.0 0.00013 22.0 0.0 1.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_14 PF13173.6 CBZ30876.1 - 5.4e-05 23.2 0.0 9.4e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.6 CBZ30876.1 - 0.00018 21.3 0.0 0.00033 20.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain TniB PF05621.11 CBZ30876.1 - 0.00019 20.9 0.0 0.0026 17.2 0.0 2.1 2 0 0 2 2 2 1 Bacterial TniB protein AAA_11 PF13086.6 CBZ30876.1 - 0.0004 20.3 0.1 0.0047 16.8 0.0 2.1 1 1 1 2 2 2 1 AAA domain AAA_23 PF13476.6 CBZ30876.1 - 0.00049 20.7 0.0 0.00063 20.3 0.0 1.3 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.12 CBZ30876.1 - 0.0014 18.4 0.0 0.0027 17.5 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_29 PF13555.6 CBZ30876.1 - 0.0021 17.8 0.0 0.0047 16.6 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain ATPase_2 PF01637.18 CBZ30876.1 - 0.0025 17.8 0.0 0.0042 17.0 0.0 1.3 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea AAA_assoc_2 PF16193.5 CBZ30876.1 - 0.0028 17.9 0.2 0.018 15.3 0.0 2.4 3 0 0 3 3 2 1 AAA C-terminal domain AAA_3 PF07726.11 CBZ30876.1 - 0.0036 17.2 0.0 0.021 14.7 0.0 2.3 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) DUF815 PF05673.13 CBZ30876.1 - 0.0063 15.7 0.0 0.01 15.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) Sigma54_activat PF00158.26 CBZ30876.1 - 0.0068 16.1 0.0 0.023 14.4 0.0 1.8 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_7 PF12775.7 CBZ30876.1 - 0.0074 15.8 0.0 0.014 14.9 0.0 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region ResIII PF04851.15 CBZ30876.1 - 0.019 15.0 0.0 0.97 9.4 0.0 2.2 1 1 0 2 2 2 0 Type III restriction enzyme, res subunit MeaB PF03308.16 CBZ30876.1 - 0.03 13.3 0.1 0.057 12.4 0.1 1.4 1 1 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB FtsK_SpoIIIE PF01580.18 CBZ30876.1 - 0.035 13.4 0.0 0.083 12.2 0.0 1.6 2 0 0 2 2 1 0 FtsK/SpoIIIE family AAA_33 PF13671.6 CBZ30876.1 - 0.046 13.9 0.0 0.094 12.9 0.0 1.6 1 1 0 1 1 1 0 AAA domain DEAD PF00270.29 CBZ30876.1 - 0.077 12.8 0.2 0.46 10.2 0.1 2.0 1 1 1 2 2 2 0 DEAD/DEAH box helicase DSBA PF01323.20 CBZ30876.1 - 0.092 12.5 0.1 0.21 11.3 0.0 1.6 2 0 0 2 2 2 0 DSBA-like thioredoxin domain NB-ARC PF00931.22 CBZ30876.1 - 0.11 11.6 0.0 3 7.0 0.0 2.2 2 0 0 2 2 2 0 NB-ARC domain IstB_IS21 PF01695.17 CBZ30876.1 - 0.14 11.8 0.0 4.1 7.1 0.0 2.5 3 0 0 3 3 3 0 IstB-like ATP binding protein DUF2075 PF09848.9 CBZ30876.1 - 0.22 10.7 0.0 0.37 10.0 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Pex19 PF04614.12 CBZ30877.1 - 4.9e-14 52.7 0.5 4.9e-14 52.7 0.5 3.6 1 1 1 3 3 3 2 Pex19 protein family Ntox34 PF15606.6 CBZ30877.1 - 0.012 15.7 0.7 0.34 11.1 0.1 2.7 2 0 0 2 2 2 0 Bacterial toxin 34 Ribosomal_L22 PF00237.19 CBZ30877.1 - 0.17 12.1 0.2 2 8.7 0.1 2.3 2 0 0 2 2 2 0 Ribosomal protein L22p/L17e PPR_2 PF13041.6 CBZ30877.1 - 0.18 12.0 0.3 0.18 12.0 0.3 2.1 2 0 0 2 2 2 0 PPR repeat family RecC_C PF17946.1 CBZ30877.1 - 0.23 11.2 1.5 0.29 10.9 0.2 1.8 2 0 0 2 2 2 0 RecC C-terminal domain HSD3 PF15244.6 CBZ30878.1 - 0.5 9.8 16.0 0.63 9.5 16.0 1.2 1 0 0 1 1 1 0 Spermatogenesis-associated protein 7, or HSD3 Ribosomal_L31e PF01198.19 CBZ30879.1 - 2e-25 88.8 0.4 2e-25 88.8 0.4 1.8 2 0 0 2 2 2 1 Ribosomal protein L31e Ribosomal_L31e PF01198.19 CBZ30880.1 - 2e-25 88.8 0.4 2e-25 88.8 0.4 1.8 2 0 0 2 2 2 1 Ribosomal protein L31e WD40 PF00400.32 CBZ30881.1 - 0.006 17.4 12.7 2.6 9.1 0.7 5.3 6 0 0 6 6 6 3 WD domain, G-beta repeat LRR_9 PF14580.6 CBZ30882.1 - 1.1e-10 41.3 0.5 3.9e-10 39.5 0.4 1.8 1 1 1 2 2 2 2 Leucine-rich repeat LRR_4 PF12799.7 CBZ30882.1 - 4.5e-09 36.5 12.3 0.00016 21.9 0.3 3.0 1 1 3 4 4 4 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CBZ30882.1 - 7.3e-07 28.9 1.7 0.00026 20.7 0.3 2.6 1 1 1 2 2 2 2 Leucine rich repeat LRR_6 PF13516.6 CBZ30882.1 - 5.1e-05 23.0 1.5 6.6 7.1 0.0 4.1 3 0 0 3 3 3 3 Leucine Rich repeat ActA PF05058.12 CBZ30882.1 - 0.062 11.7 0.2 0.087 11.2 0.2 1.1 1 0 0 1 1 1 0 ActA Protein LRR_1 PF00560.33 CBZ30882.1 - 8.2 7.4 5.9 17 6.4 0.0 3.9 4 1 0 4 4 4 0 Leucine Rich Repeat TRAPP PF04051.16 CBZ30883.1 - 5e-25 87.9 0.0 5.9e-25 87.7 0.0 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component Mito_carr PF00153.27 CBZ30884.1 - 6.9e-54 179.8 0.5 3.6e-19 68.5 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein 6PGD PF00393.19 CBZ30885.1 - 4.7e-75 252.7 0.0 6.5e-75 252.2 0.0 1.2 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.15 CBZ30885.1 - 1.1e-46 158.9 0.1 1.7e-46 158.3 0.1 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase Shikimate_DH PF01488.20 CBZ30885.1 - 3.1e-06 27.3 0.2 2.2e-05 24.6 0.1 2.1 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase 3HCDH_N PF02737.18 CBZ30885.1 - 3e-05 24.0 0.1 5.2e-05 23.2 0.1 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain F420_oxidored PF03807.17 CBZ30885.1 - 8.2e-05 23.1 0.2 0.0002 21.9 0.2 1.7 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_Gly3P_dh_N PF01210.23 CBZ30885.1 - 0.0021 18.1 0.0 0.0061 16.6 0.0 1.8 2 0 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus 2-Hacid_dh_C PF02826.19 CBZ30885.1 - 0.0042 16.5 0.2 0.01 15.2 0.2 1.7 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ApbA PF02558.16 CBZ30885.1 - 0.14 11.8 0.0 0.26 10.9 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA IlvN PF07991.12 CBZ30885.1 - 0.16 11.5 0.0 0.28 10.8 0.0 1.4 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain TP_methylase PF00590.20 CBZ30886.1 - 3.7e-19 69.5 2.5 2.5e-18 66.8 0.1 2.7 2 2 0 2 2 2 1 Tetrapyrrole (Corrin/Porphyrin) Methylases DUF2428 PF10350.9 CBZ30887.1 - 1.5e-34 119.5 0.1 5.3e-34 117.7 0.0 2.1 2 0 0 2 2 2 1 Putative death-receptor fusion protein (DUF2428) HEAT PF02985.22 CBZ30887.1 - 0.17 12.2 8.2 29 5.3 0.1 5.6 4 0 0 4 4 4 0 HEAT repeat PARP_regulatory PF01358.18 CBZ30889.1 - 1.3e-14 53.9 0.0 2e-09 36.8 0.0 2.6 2 1 0 2 2 2 2 Poly A polymerase regulatory subunit DUF5423 PF17461.2 CBZ30889.1 - 0.015 14.1 1.9 0.024 13.5 1.9 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5423) Sporozoite_P67 PF05642.11 CBZ30889.1 - 0.18 9.8 0.2 0.25 9.4 0.2 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen CDC50 PF03381.15 CBZ30891.1 - 2.2e-72 243.9 0.0 2.8e-72 243.6 0.0 1.0 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family Rep_fac-A_3 PF08661.11 CBZ30895.1 - 2.9e-07 30.8 0.0 6.7e-07 29.6 0.0 1.6 1 1 0 1 1 1 1 Replication factor A protein 3 Rad4 PF03835.15 CBZ30896.1 - 5.1e-20 71.7 0.2 1.2e-19 70.4 0.2 1.6 1 0 0 1 1 1 1 Rad4 transglutaminase-like domain BHD_3 PF10405.9 CBZ30896.1 - 1.1e-14 54.6 0.0 1.9e-14 53.8 0.0 1.4 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 3 BHD_1 PF10403.9 CBZ30896.1 - 9.4e-10 38.2 0.0 1.7e-09 37.4 0.0 1.4 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 1 BHD_2 PF10404.9 CBZ30896.1 - 0.0021 19.0 5.7 0.017 16.1 0.9 3.3 2 1 0 2 2 2 1 Rad4 beta-hairpin domain 2 Transglut_core PF01841.19 CBZ30896.1 - 1.1 9.7 4.3 9.7 6.7 0.1 3.7 3 1 0 4 4 4 0 Transglutaminase-like superfamily peroxidase PF00141.23 CBZ30897.1 - 3.7e-08 33.4 0.0 4.3e-08 33.1 0.0 1.3 1 1 0 1 1 1 1 Peroxidase Acyl_transf_1 PF00698.21 CBZ30898.1 - 3.6e-19 69.4 0.0 1.8e-18 67.1 0.0 2.1 1 1 0 1 1 1 1 Acyl transferase domain FYVE PF01363.21 CBZ30901.1 - 1.1e-18 67.1 7.9 1.7e-18 66.5 7.9 1.3 1 0 0 1 1 1 1 FYVE zinc finger OrfB_Zn_ribbon PF07282.11 CBZ30901.1 - 5.7 7.0 9.1 13 5.8 9.1 1.6 1 0 0 1 1 1 0 Putative transposase DNA-binding domain DZR PF12773.7 CBZ30901.1 - 9.4 6.4 12.4 1.8e+03 -1.0 12.7 2.3 1 1 0 1 1 1 0 Double zinc ribbon SMC_N PF02463.19 CBZ30902.1 - 1.5e-55 188.1 0.0 2.9e-54 183.8 0.0 2.2 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 CBZ30902.1 - 3.3e-26 91.9 0.0 1.5e-25 89.8 0.0 2.3 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.6 CBZ30902.1 - 1.3e-13 51.4 0.0 1.3e-06 28.5 0.0 2.5 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 CBZ30902.1 - 4.2e-11 43.7 12.6 4.2e-11 43.7 12.6 5.2 3 1 1 4 4 3 1 AAA domain AAA_15 PF13175.6 CBZ30902.1 - 6.9e-09 35.9 0.0 6.9e-09 35.9 0.0 3.7 3 2 2 5 5 4 1 AAA ATPase domain AAA_29 PF13555.6 CBZ30902.1 - 8.5e-07 28.6 0.0 2e-06 27.5 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 CBZ30902.1 - 0.0042 17.0 0.9 0.036 14.0 0.0 3.1 2 0 0 2 2 2 1 RsgA GTPase ABC_tran PF00005.27 CBZ30902.1 - 0.042 14.4 0.0 0.042 14.4 0.0 5.5 4 2 0 4 4 3 0 ABC transporter AAA_22 PF13401.6 CBZ30902.1 - 0.18 12.0 5.8 7.5 6.8 0.0 4.4 3 2 1 4 4 4 0 AAA domain AAA_5 PF07728.14 CBZ30902.1 - 0.73 9.8 7.1 3.6 7.6 0.0 4.4 5 0 0 5 5 5 0 AAA domain (dynein-related subfamily) Baculo_PEP_C PF04513.12 CBZ30902.1 - 9.6 6.2 20.6 1.2 9.1 0.5 5.2 4 1 1 5 5 5 0 Baculovirus polyhedron envelope protein, PEP, C terminus NIF PF03031.18 CBZ30903.1 - 5.9e-30 104.1 0.0 5.1e-16 58.8 0.0 2.5 2 0 0 2 2 2 2 NLI interacting factor-like phosphatase PaO PF08417.12 CBZ30903.1 - 0.067 13.3 0.4 9.2 6.5 0.1 2.6 2 1 0 2 2 2 0 Pheophorbide a oxygenase KH_1 PF00013.29 CBZ30905.1 - 0.0011 18.7 0.4 0.0031 17.3 0.4 1.7 1 0 0 1 1 1 1 KH domain KH_8 PF17903.1 CBZ30905.1 - 0.052 13.7 0.2 0.33 11.1 0.2 2.1 1 1 0 1 1 1 0 Krr1 KH1 domain DUF2497 PF10691.9 CBZ30906.1 - 0.015 15.7 0.2 0.015 15.7 0.2 3.3 2 1 1 3 3 3 0 Protein of unknown function (DUF2497) DUF842 PF05811.13 CBZ30906.1 - 0.064 12.9 11.6 0.11 12.2 9.3 2.5 2 1 1 3 3 3 0 Eukaryotic protein of unknown function (DUF842) Rx_N PF18052.1 CBZ30906.1 - 0.1 12.9 10.0 0.1 12.9 2.2 3.2 2 1 1 3 3 3 0 Rx N-terminal domain HIP1_clath_bdg PF16515.5 CBZ30906.1 - 0.13 12.9 23.7 1.1 9.9 6.3 3.0 1 1 1 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Baculo_PEP_C PF04513.12 CBZ30906.1 - 0.74 9.9 6.1 0.86 9.6 1.1 2.9 2 1 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF4407 PF14362.6 CBZ30906.1 - 1.8 7.9 21.6 2.6 7.3 0.0 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) DUF1664 PF07889.12 CBZ30906.1 - 2.8 8.0 15.1 1.3 9.1 3.1 4.0 3 1 3 6 6 6 0 Protein of unknown function (DUF1664) Exonuc_VII_L PF02601.15 CBZ30906.1 - 3.2 7.2 20.7 8.3 5.9 20.3 1.8 1 1 0 1 1 1 0 Exonuclease VII, large subunit MIP-T3_C PF17749.1 CBZ30906.1 - 5.9 6.8 15.7 3 7.8 12.1 2.3 1 1 1 2 2 2 0 Microtubule-binding protein MIP-T3 C-terminal region DUF713 PF05218.14 CBZ30906.1 - 9.3 5.9 9.5 14 5.4 1.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF713) CRAL_TRIO PF00650.20 CBZ30907.1 - 2.3e-24 85.9 0.1 3.6e-24 85.3 0.1 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 CBZ30907.1 - 2.9e-06 27.4 0.3 7.3e-06 26.1 0.3 1.7 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain FUSC_2 PF13515.6 CBZ30908.1 - 4.5e-09 36.5 3.7 4.5e-09 36.5 3.7 2.3 2 0 0 2 2 2 1 Fusaric acid resistance protein-like MatE PF01554.18 CBZ30909.1 - 1.2e-30 106.3 26.8 6.8e-17 61.6 10.9 2.2 2 0 0 2 2 2 2 MatE DUF5408 PF17402.2 CBZ30909.1 - 0.14 12.0 1.5 0.61 10.0 1.5 2.1 1 0 0 1 1 1 0 Family of unknown function (DUF5408) XPG_I_2 PF12813.7 CBZ30910.1 - 1.1e-38 133.1 0.0 1.7e-38 132.5 0.0 1.3 1 0 0 1 1 1 1 XPG domain containing XPG_I PF00867.18 CBZ30910.1 - 3.3e-20 72.2 0.2 6.3e-20 71.3 0.2 1.5 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.17 CBZ30910.1 - 1.2e-19 70.7 0.0 3.1e-19 69.3 0.0 1.7 2 0 0 2 2 2 1 XPG N-terminal domain Methyltransf_23 PF13489.6 CBZ30911.1 - 5.6e-28 97.8 0.0 7.9e-28 97.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CBZ30911.1 - 0.0098 16.6 0.2 0.2 12.4 0.0 3.0 4 1 0 4 4 4 1 Methyltransferase domain Pro_isomerase PF00160.21 CBZ30912.1 - 8.5e-29 100.9 0.0 2.8e-28 99.2 0.0 1.8 2 0 0 2 2 2 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD NifU_N PF01592.16 CBZ30913.1 - 4.4e-50 169.1 0.0 5.9e-50 168.7 0.0 1.1 1 0 0 1 1 1 1 NifU-like N terminal domain MatE PF01554.18 CBZ30914.1 - 6e-33 113.8 32.3 2.6e-17 62.9 12.9 3.4 3 0 0 3 3 3 3 MatE TfuA PF07812.12 CBZ30914.1 - 0.12 12.1 0.0 0.33 10.7 0.0 1.7 1 0 0 1 1 1 0 TfuA-like protein DUF1970 PF09301.10 CBZ30916.1 - 2 8.7 9.8 4.1 7.7 1.7 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF1970) NDUF_B7 PF05676.13 CBZ30918.1 - 7e-09 35.3 0.5 1.2e-08 34.6 0.5 1.3 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) Baculo_VP39 PF04501.12 CBZ30918.1 - 0.085 12.3 0.1 0.11 12.0 0.1 1.1 1 0 0 1 1 1 0 Baculovirus major capsid protein VP39 PEX11 PF05648.14 CBZ30919.1 - 7.3e-08 32.2 0.0 8.5e-08 31.9 0.0 1.1 1 0 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) PEX11 PF05648.14 CBZ30920.1 - 1.3e-12 47.6 0.0 1.7e-12 47.3 0.0 1.3 1 1 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) Vir_act_alpha_C PF10400.9 CBZ30921.1 - 0.027 15.1 4.3 0.052 14.2 4.3 1.3 1 0 0 1 1 1 0 Virulence activator alpha C-term DUF4190 PF13828.6 CBZ30921.1 - 0.26 11.1 2.2 0.4 10.5 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4190) LPD23 PF18838.1 CBZ30922.1 - 0.12 12.2 0.2 0.12 12.2 0.2 2.7 3 0 0 3 3 3 0 Large polyvalent protein associated domain 23 PhyH PF05721.13 CBZ30924.1 - 0.11 12.7 0.0 0.63 10.3 0.0 2.1 2 1 0 2 2 2 0 Phytanoyl-CoA dioxygenase (PhyH) Cullin PF00888.22 CBZ30925.1 - 2.9e-16 59.2 0.0 4.2e-16 58.7 0.0 1.1 1 0 0 1 1 1 1 Cullin family Antibiotic_NAT PF02522.14 CBZ30925.1 - 0.0092 15.8 0.2 0.023 14.5 0.0 1.7 2 0 0 2 2 2 1 Aminoglycoside 3-N-acetyltransferase Ribosomal_L27A PF00828.19 CBZ30926.1 - 5.2e-21 75.6 0.1 6.7e-21 75.3 0.1 1.1 1 0 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A Ribosomal_L27A PF00828.19 CBZ30928.1 - 5.2e-21 75.6 0.1 6.7e-21 75.3 0.1 1.1 1 0 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A Ribosomal_L14 PF00238.19 CBZ30929.1 - 4.3e-37 126.9 0.0 5.1e-37 126.7 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e PAS PF00989.25 CBZ30929.1 - 0.21 11.6 0.0 0.27 11.3 0.0 1.2 1 0 0 1 1 1 0 PAS fold Ribosomal_L14 PF00238.19 CBZ30930.1 - 4.3e-37 126.9 0.0 5.1e-37 126.7 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e PAS PF00989.25 CBZ30930.1 - 0.21 11.6 0.0 0.27 11.3 0.0 1.2 1 0 0 1 1 1 0 PAS fold Cep57_CLD_2 PF14197.6 CBZ30932.1 - 0.0096 16.0 1.9 0.0096 16.0 1.9 3.8 3 1 0 3 3 3 1 Centrosome localisation domain of PPC89 DUF4715 PF15835.5 CBZ30932.1 - 0.69 10.0 5.6 0.083 13.0 0.8 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4715) CENP-F_leu_zip PF10473.9 CBZ30932.1 - 1.5 8.8 15.7 0.32 11.0 2.4 3.0 2 1 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF4695 PF15766.5 CBZ30932.1 - 1.9 8.8 19.3 0.19 11.9 5.0 3.1 3 1 1 4 4 4 0 Domain of unknown function (DUF4695) SET PF00856.28 CBZ30933.1 - 3.5e-05 24.3 0.0 5.6e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 SET domain Proteasome PF00227.26 CBZ30934.1 - 4.7e-48 163.2 0.5 5.6e-48 163.0 0.5 1.1 1 0 0 1 1 1 1 Proteasome subunit Pr_beta_C PF12465.8 CBZ30934.1 - 0.007 15.7 2.4 0.012 15.0 0.0 2.3 2 0 0 2 2 2 1 Proteasome beta subunits C terminal sCache_2 PF17200.4 CBZ30934.1 - 0.2 11.5 0.0 0.32 10.8 0.0 1.3 1 0 0 1 1 1 0 Single Cache domain 2 Ribosomal_S17 PF00366.20 CBZ30935.1 - 9.4e-18 64.1 0.4 1.9e-17 63.1 0.4 1.5 1 0 0 1 1 1 1 Ribosomal protein S17 Cpn60_TCP1 PF00118.24 CBZ30936.1 - 3.3e-157 524.0 2.8 4.2e-157 523.7 2.8 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family NDK PF00334.19 CBZ30937.1 - 3.1e-30 105.0 0.0 1.8e-27 96.0 0.0 2.4 2 1 0 2 2 2 2 Nucleoside diphosphate kinase DUF1126 PF06565.12 CBZ30937.1 - 1.1e-05 25.1 0.0 4.2e-05 23.3 0.1 1.9 2 0 0 2 2 2 1 DUF1126 PH-like domain WD40 PF00400.32 CBZ30938.1 - 1.8e-30 104.5 15.8 6.2e-09 36.4 0.0 7.3 7 0 0 7 7 7 5 WD domain, G-beta repeat Sof1 PF04158.14 CBZ30938.1 - 8.3e-10 38.8 6.1 1.6e-09 37.9 6.1 1.4 1 0 0 1 1 1 1 Sof1-like domain ANAPC4_WD40 PF12894.7 CBZ30938.1 - 3.7e-05 23.9 0.1 0.31 11.4 0.0 4.4 2 1 3 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 CBZ30938.1 - 0.00019 20.5 0.2 0.97 8.3 0.0 3.1 3 0 0 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 CBZ30938.1 - 0.00061 19.7 0.0 0.0032 17.4 0.0 2.1 2 1 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 CBZ30938.1 - 0.012 15.0 0.0 2.9 7.1 0.0 2.8 3 0 0 3 3 3 0 WD40-like domain Nup160 PF11715.8 CBZ30938.1 - 0.86 8.2 5.7 18 3.8 0.1 3.6 3 2 1 4 4 4 0 Nucleoporin Nup120/160 EF-hand_7 PF13499.6 CBZ30939.1 - 3.7e-12 46.5 1.8 4e-06 27.2 0.9 2.3 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 CBZ30939.1 - 8.6e-09 34.3 3.7 4.5e-08 32.1 0.1 3.4 4 0 0 4 4 4 1 EF hand EF-hand_6 PF13405.6 CBZ30939.1 - 1.5e-08 33.9 0.1 3.2e-06 26.6 0.0 3.4 3 1 1 4 4 4 1 EF-hand domain EF-hand_8 PF13833.6 CBZ30939.1 - 2.2e-08 33.8 1.7 3e-05 23.8 0.4 3.3 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.6 CBZ30939.1 - 0.00013 21.3 0.0 0.00013 21.3 0.0 2.4 3 0 0 3 3 3 1 EF hand EF-hand_9 PF14658.6 CBZ30939.1 - 0.0057 17.0 0.1 1.3 9.4 0.0 2.3 2 0 0 2 2 2 2 EF-hand domain UPF0154 PF03672.13 CBZ30939.1 - 0.086 12.9 0.0 1.1 9.3 0.0 2.1 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0154) PhetRS_B1 PF18262.1 CBZ30939.1 - 0.1 12.9 0.0 0.64 10.3 0.0 2.0 2 0 0 2 2 2 0 Phe-tRNA synthetase beta subunit B1 domain EF-hand_14 PF17959.1 CBZ30939.1 - 0.12 12.7 0.0 6.3 7.2 0.0 2.2 1 1 1 2 2 2 0 EF-hand domain Rhodanese_C PF12368.8 CBZ30942.1 - 0.11 12.9 10.0 0.52 10.7 2.6 2.7 2 0 0 2 2 2 0 Rhodanase C-terminal SHIPPO-rpt PF07004.12 CBZ30943.1 - 2.3e-15 56.7 47.1 0.095 13.6 5.1 10.1 10 0 0 10 10 10 8 Sperm-tail PG-rich repeat ECR1_N PF14382.6 CBZ30943.1 - 5.7 6.8 9.7 8.9 6.2 0.1 4.8 6 0 0 6 6 6 0 Exosome complex exonuclease RRP4 N-terminal region UNC-50 PF05216.13 CBZ30944.1 - 2.1e-44 151.7 9.5 2.6e-44 151.4 9.5 1.0 1 0 0 1 1 1 1 UNC-50 family EMC3_TMCO1 PF01956.16 CBZ30944.1 - 1.1 9.0 6.0 0.13 12.0 1.6 1.8 2 1 0 2 2 2 0 Integral membrane protein EMC3/TMCO1-like INCENP_N PF12178.8 CBZ30945.1 - 0.00053 19.9 0.2 0.0011 19.0 0.2 1.5 1 0 0 1 1 1 1 Chromosome passenger complex (CPC) protein INCENP N terminal PROCN PF08083.11 CBZ30946.1 - 5.7e-191 634.6 3.6 1.3e-190 633.4 3.6 1.6 1 0 0 1 1 1 1 PROCN (NUC071) domain PRP8_domainIV PF12134.8 CBZ30946.1 - 1.1e-90 303.3 0.0 1.7e-90 302.7 0.0 1.3 1 0 0 1 1 1 1 PRP8 domain IV core U6-snRNA_bdg PF10596.9 CBZ30946.1 - 3.6e-69 231.8 0.1 8.1e-69 230.6 0.1 1.6 1 0 0 1 1 1 1 U6-snRNA interacting domain of PrP8 U5_2-snRNA_bdg PF10597.9 CBZ30946.1 - 1.6e-58 196.6 0.1 3.5e-58 195.5 0.1 1.6 1 0 0 1 1 1 1 U5-snRNA binding site 2 of PrP8 PRO8NT PF08082.11 CBZ30946.1 - 4.7e-58 195.5 0.0 1.4e-57 193.9 0.0 1.9 1 0 0 1 1 1 1 PRO8NT (NUC069), PrP8 N-terminal domain RRM_4 PF10598.9 CBZ30946.1 - 1.4e-36 124.7 0.1 4.3e-36 123.1 0.1 1.9 1 0 0 1 1 1 1 RNA recognition motif of the spliceosomal PrP8 PROCT PF08084.11 CBZ30946.1 - 1e-29 103.0 0.0 2.1e-29 101.9 0.0 1.6 1 0 0 1 1 1 1 PROCT (NUC072) domain DUF5480 PF17576.2 CBZ30946.1 - 0.04 13.9 0.3 0.09 12.8 0.3 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5480) Pkinase PF00069.25 CBZ30947.1 - 3.4e-68 229.9 0.0 4.1e-68 229.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ30947.1 - 9.3e-33 113.6 0.0 1.2e-32 113.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CBZ30947.1 - 5.8e-05 22.5 0.0 7.6e-05 22.2 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_C PF00433.24 CBZ30947.1 - 0.0095 16.6 0.3 0.022 15.5 0.3 1.7 1 0 0 1 1 1 1 Protein kinase C terminal domain Haspin_kinase PF12330.8 CBZ30947.1 - 0.014 14.4 0.1 0.019 13.9 0.1 1.1 1 0 0 1 1 1 0 Haspin like kinase domain POR PF01558.18 CBZ30947.1 - 0.085 12.9 0.0 0.13 12.3 0.0 1.2 1 0 0 1 1 1 0 Pyruvate ferredoxin/flavodoxin oxidoreductase zf-MIZ PF02891.20 CBZ30948.1 - 4.7e-20 71.1 1.3 1e-19 70.0 1.3 1.6 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger zf-Nse PF11789.8 CBZ30948.1 - 8.9e-05 22.2 0.1 0.00021 21.0 0.1 1.5 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit Mito_carr PF00153.27 CBZ30950.1 - 5.4e-40 135.2 0.7 3.1e-20 71.9 0.0 2.1 2 0 0 2 2 2 2 Mitochondrial carrier protein HECT PF00632.25 CBZ30951.1 - 2.6e-48 165.1 0.0 4.4e-48 164.4 0.0 1.3 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Pkinase PF00069.25 CBZ30951.1 - 5.9e-45 153.7 0.0 1.1e-44 152.7 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ30951.1 - 5.9e-29 101.1 0.0 1.9e-28 99.5 0.0 1.9 2 1 0 2 2 2 1 Protein tyrosine kinase TPR_1 PF00515.28 CBZ30951.1 - 3.5e-13 48.8 2.3 5.4e-06 26.0 0.0 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 CBZ30951.1 - 5.5e-13 48.0 4.0 3.2e-05 23.7 0.1 4.1 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_8 PF13181.6 CBZ30951.1 - 2.6e-11 42.8 1.6 0.0046 17.1 0.0 3.9 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.6 CBZ30951.1 - 1.8e-09 37.1 0.7 1.2e-05 24.8 0.2 3.2 2 1 1 3 3 3 2 TPR repeat Kinase-like PF14531.6 CBZ30951.1 - 4e-05 23.1 0.0 0.00011 21.6 0.0 1.7 1 0 0 1 1 1 1 Kinase-like TPR_16 PF13432.6 CBZ30951.1 - 0.0003 21.4 0.3 0.0003 21.4 0.3 2.9 2 1 1 3 3 2 1 Tetratricopeptide repeat APH PF01636.23 CBZ30951.1 - 0.00033 20.7 0.0 0.00033 20.7 0.0 2.5 2 0 0 2 2 2 1 Phosphotransferase enzyme family TPR_7 PF13176.6 CBZ30951.1 - 0.00062 19.6 3.1 0.014 15.3 0.1 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat RIO1 PF01163.22 CBZ30951.1 - 0.005 16.5 0.0 0.015 14.9 0.0 1.8 1 0 0 1 1 1 1 RIO1 family TPR_12 PF13424.6 CBZ30951.1 - 0.006 16.8 0.2 0.36 11.2 0.0 3.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_17 PF13431.6 CBZ30951.1 - 0.008 16.5 0.5 1.6 9.2 0.0 3.4 3 0 0 3 3 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 CBZ30951.1 - 0.0095 16.7 10.7 0.51 11.3 0.0 4.4 5 0 0 5 5 2 2 Tetratricopeptide repeat TPR_19 PF14559.6 CBZ30951.1 - 0.0095 16.4 7.3 0.31 11.6 0.0 4.2 4 1 1 5 5 3 1 Tetratricopeptide repeat EMP24_GP25L PF01105.24 CBZ30951.1 - 0.015 15.2 2.0 0.029 14.3 0.7 1.8 1 1 0 1 1 1 0 emp24/gp25L/p24 family/GOLD tRNA-synt_2c PF01411.19 CBZ30951.1 - 0.019 13.5 3.6 0.035 12.6 3.6 1.4 1 0 0 1 1 1 0 tRNA synthetases class II (A) TPR_9 PF13371.6 CBZ30951.1 - 0.047 13.8 0.1 19 5.5 0.0 3.1 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.6 CBZ30951.1 - 0.063 13.9 0.2 3.1 8.6 0.0 3.3 2 0 0 2 2 2 0 Tetratricopeptide repeat DnaB_2 PF07261.11 CBZ30951.1 - 0.12 12.1 0.0 0.31 10.8 0.0 1.6 1 0 0 1 1 1 0 Replication initiation and membrane attachment MIT PF04212.18 CBZ30951.1 - 2.2 8.4 6.6 0.87 9.7 0.3 3.5 3 0 0 3 3 2 0 MIT (microtubule interacting and transport) domain TPR_10 PF13374.6 CBZ30951.1 - 3.4 7.6 5.1 29 4.7 0.1 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat Pkinase PF00069.25 CBZ30952.1 - 1.4e-68 231.2 0.0 1.6e-68 230.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ30952.1 - 6.4e-33 114.1 0.0 8.4e-33 113.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CBZ30952.1 - 4.8e-05 22.8 0.0 6.6e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 CBZ30952.1 - 0.013 14.4 0.1 0.018 14.0 0.1 1.1 1 0 0 1 1 1 0 Haspin like kinase domain Pkinase_C PF00433.24 CBZ30952.1 - 0.018 15.7 0.3 0.049 14.4 0.3 1.8 1 0 0 1 1 1 0 Protein kinase C terminal domain POR PF01558.18 CBZ30952.1 - 0.084 12.9 0.0 0.14 12.2 0.0 1.2 1 0 0 1 1 1 0 Pyruvate ferredoxin/flavodoxin oxidoreductase Hydrolase_4 PF12146.8 CBZ30953.1 - 2.2e-15 56.6 0.1 5.6e-10 38.9 0.0 2.4 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 CBZ30953.1 - 6.4e-10 39.1 0.0 5.9e-07 29.4 0.1 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 CBZ30953.1 - 5e-07 30.5 0.2 1.4e-06 29.1 0.0 1.8 2 1 0 2 2 2 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 CBZ30953.1 - 6.5e-06 25.8 0.0 4.8e-05 22.9 0.0 2.2 1 1 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_2 PF02230.16 CBZ30953.1 - 1.7e-05 24.7 0.0 0.05 13.4 0.0 2.3 1 1 1 2 2 2 2 Phospholipase/Carboxylesterase Abhydrolase_3 PF07859.13 CBZ30953.1 - 2.5e-05 24.2 0.3 5.3e-05 23.2 0.3 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold AXE1 PF05448.12 CBZ30953.1 - 0.00024 19.9 0.0 0.0028 16.4 0.0 2.1 2 0 0 2 2 2 1 Acetyl xylan esterase (AXE1) DLH PF01738.18 CBZ30953.1 - 0.00027 20.6 0.0 0.049 13.2 0.0 2.1 1 1 0 2 2 2 1 Dienelactone hydrolase family BAAT_C PF08840.11 CBZ30953.1 - 0.00061 19.8 0.0 0.0014 18.6 0.0 1.5 1 1 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal Peptidase_S15 PF02129.18 CBZ30953.1 - 0.0039 16.8 0.0 1.7 8.2 0.0 2.2 2 0 0 2 2 2 2 X-Pro dipeptidyl-peptidase (S15 family) DUF818 PF05677.12 CBZ30953.1 - 0.015 14.3 0.0 0.021 13.8 0.0 1.2 1 0 0 1 1 1 0 Chlamydia CHLPS protein (DUF818) FSH1 PF03959.13 CBZ30953.1 - 0.033 13.8 0.0 0.048 13.3 0.0 1.3 1 0 0 1 1 1 0 Serine hydrolase (FSH1) DUF1100 PF06500.11 CBZ30953.1 - 0.041 12.7 0.0 0.05 12.4 0.0 1.1 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1100) Abhydrolase_5 PF12695.7 CBZ30953.1 - 0.077 12.8 0.0 0.78 9.5 0.0 2.0 1 1 0 2 2 2 0 Alpha/beta hydrolase family UPF0227 PF05728.12 CBZ30953.1 - 0.088 12.7 0.0 0.23 11.4 0.0 1.7 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0227) BMF PF15185.6 CBZ30953.1 - 0.18 11.5 0.1 0.3 10.8 0.1 1.3 1 0 0 1 1 1 0 Bcl-2-modifying factor, apoptosis DEAD PF00270.29 CBZ30954.1 - 9.5e-38 129.7 0.0 3.4e-37 127.9 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CBZ30954.1 - 6.2e-24 84.5 0.0 2.7e-23 82.4 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 CBZ30954.1 - 1.9e-13 50.4 0.0 5.6e-13 48.9 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.15 CBZ30954.1 - 0.00017 21.7 0.0 0.00043 20.3 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DUF2009 PF09418.10 CBZ30954.1 - 0.36 9.8 4.6 2.4 7.1 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF2009) DnaJ PF00226.31 CBZ30955.1 - 5e-15 55.4 0.0 1.9e-09 37.5 0.0 2.5 2 0 0 2 2 2 2 DnaJ domain SUIM_assoc PF16619.5 CBZ30955.1 - 0.13 12.4 9.2 0.13 12.3 4.3 2.7 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 TFIIA PF03153.13 CBZ30955.1 - 0.28 11.1 6.9 0.35 10.8 6.9 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Pkinase PF00069.25 CBZ30957.1 - 2.1e-38 132.2 0.0 1.3e-37 129.7 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ30957.1 - 2.8e-20 72.7 0.0 9.9e-20 70.9 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CBZ30957.1 - 1.9e-09 37.3 0.0 4.1e-09 36.2 0.0 1.5 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 CBZ30957.1 - 0.0051 16.8 0.0 0.013 15.4 0.0 1.7 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIIa PF02197.17 CBZ30958.1 - 7.5e-11 41.5 0.0 2.3e-10 39.9 0.0 1.9 1 0 0 1 1 1 1 Regulatory subunit of type II PKA R-subunit EF-hand_6 PF13405.6 CBZ30958.1 - 4.2e-05 23.1 0.1 0.08 12.9 0.0 3.2 3 0 0 3 3 3 2 EF-hand domain EF-hand_7 PF13499.6 CBZ30958.1 - 0.00044 20.6 0.0 0.55 10.7 0.0 2.5 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 CBZ30958.1 - 0.053 13.1 0.1 3.7 7.3 0.0 3.1 3 0 0 3 3 3 0 EF hand TPR_2 PF07719.17 CBZ30959.1 - 7.8e-14 50.6 14.1 0.0067 16.5 0.0 6.9 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_19 PF14559.6 CBZ30959.1 - 9.6e-12 45.2 14.3 2.6e-05 24.7 1.1 5.4 3 2 2 5 5 5 3 Tetratricopeptide repeat TPR_12 PF13424.6 CBZ30959.1 - 6.5e-11 42.4 20.5 0.00064 20.0 0.1 5.3 3 1 3 6 6 6 5 Tetratricopeptide repeat TPR_14 PF13428.6 CBZ30959.1 - 2.3e-09 37.3 19.8 0.00026 21.5 0.4 6.8 3 3 4 7 7 7 4 Tetratricopeptide repeat TPR_17 PF13431.6 CBZ30959.1 - 1.7e-06 28.0 5.5 0.68 10.5 0.1 5.1 4 1 0 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.6 CBZ30959.1 - 2.3e-06 28.1 14.8 0.023 15.4 1.6 4.5 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_8 PF13181.6 CBZ30959.1 - 4.1e-06 26.6 4.1 2.5 8.5 0.0 6.4 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_6 PF13174.6 CBZ30959.1 - 1.5e-05 25.3 8.6 0.72 10.6 0.0 5.5 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_1 PF00515.28 CBZ30959.1 - 1.6e-05 24.5 12.1 2.3 8.2 1.3 6.3 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_15 PF13429.6 CBZ30959.1 - 4e-05 23.0 6.5 0.01 15.1 0.5 3.0 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.6 CBZ30959.1 - 0.00027 20.8 16.6 0.025 14.6 0.1 5.5 5 1 0 5 5 5 2 Tetratricopeptide repeat DUF218 PF02698.17 CBZ30959.1 - 0.0045 17.0 0.6 0.015 15.4 0.2 2.0 2 1 0 2 2 2 1 DUF218 domain TPR_4 PF07721.14 CBZ30959.1 - 0.0085 16.6 16.1 0.11 13.2 0.3 5.1 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_11 PF13414.6 CBZ30959.1 - 0.012 15.3 10.7 7.2 6.4 0.2 6.4 6 1 1 7 7 7 0 TPR repeat ANAPC3 PF12895.7 CBZ30959.1 - 0.015 15.5 9.2 1.4 9.2 2.3 3.5 3 1 1 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 Alkyl_sulf_dimr PF14863.6 CBZ30959.1 - 0.23 11.9 2.4 0.37 11.2 0.7 2.2 1 1 1 2 2 2 0 Alkyl sulfatase dimerisation HEAT_2 PF13646.6 CBZ30959.1 - 0.48 10.8 4.7 15 6.0 0.5 3.5 3 1 1 4 4 3 0 HEAT repeats MIT PF04212.18 CBZ30959.1 - 0.76 9.9 9.7 0.56 10.3 0.7 3.7 3 0 0 3 3 3 0 MIT (microtubule interacting and transport) domain TPR_21 PF09976.9 CBZ30959.1 - 1.2 8.9 9.2 13 5.4 0.5 3.1 1 1 2 3 3 3 0 Tetratricopeptide repeat-like domain SF3b10 PF07189.11 CBZ30961.1 - 1.2e-16 60.6 0.0 1.2e-16 60.5 0.0 1.0 1 0 0 1 1 1 1 Splicing factor 3B subunit 10 (SF3b10) SseB PF07179.12 CBZ30962.1 - 0.036 14.3 0.0 6.2 7.1 0.0 2.3 2 0 0 2 2 2 0 SseB protein N-terminal domain HD_3 PF13023.6 CBZ30963.1 - 1.8e-37 128.8 0.0 2.1e-37 128.6 0.0 1.2 1 0 0 1 1 1 1 HD domain HD_2 PF12917.7 CBZ30963.1 - 6e-11 42.4 0.0 9.4e-11 41.8 0.0 1.3 1 0 0 1 1 1 1 HD containing hydrolase-like enzyme HD PF01966.22 CBZ30963.1 - 8.3e-06 26.0 0.0 1.4e-05 25.3 0.0 1.4 1 0 0 1 1 1 1 HD domain RRM_1 PF00076.22 CBZ30966.1 - 8e-73 240.2 0.1 4.1e-17 61.8 0.0 4.3 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP PF00658.18 CBZ30966.1 - 1.2e-24 86.3 0.1 2.2e-24 85.4 0.1 1.5 1 0 0 1 1 1 1 Poly-adenylate binding protein, unique domain RRM_occluded PF16842.5 CBZ30966.1 - 3.1e-09 36.5 0.0 0.075 12.9 0.0 3.9 4 0 0 4 4 4 3 Occluded RNA-recognition motif RRM_3 PF08777.11 CBZ30966.1 - 6.7e-08 32.5 2.7 0.28 11.3 0.3 4.3 3 1 1 4 4 4 4 RNA binding motif Nup35_RRM_2 PF14605.6 CBZ30966.1 - 1.1e-07 31.7 0.1 0.023 14.7 0.0 3.9 4 0 0 4 4 4 2 Nup53/35/40-type RNA recognition motif RRM_7 PF16367.5 CBZ30966.1 - 2e-05 24.6 0.0 0.2 11.8 0.0 5.0 5 2 0 5 5 5 1 RNA recognition motif RRM_5 PF13893.6 CBZ30966.1 - 0.0001 21.9 0.0 0.017 14.7 0.0 2.7 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.8 CBZ30966.1 - 0.084 13.0 0.2 7.9 6.6 0.0 3.4 3 0 0 3 3 3 0 Limkain b1 TB2_DP1_HVA22 PF03134.19 CBZ30967.1 - 0.14 12.1 3.4 0.076 13.0 1.2 1.7 2 0 0 2 2 2 0 TB2/DP1, HVA22 family GTP_EFTU PF00009.27 CBZ30968.1 - 2e-41 141.7 0.1 1.3e-39 135.8 0.0 2.2 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 CBZ30968.1 - 1e-13 51.5 0.0 2.1e-13 50.6 0.0 1.5 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain MMR_HSR1 PF01926.23 CBZ30968.1 - 0.0015 18.6 0.0 0.0069 16.5 0.0 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D2 PF03144.25 CBZ30968.1 - 0.025 14.9 0.1 0.065 13.6 0.1 1.8 1 0 0 1 1 1 0 Elongation factor Tu domain 2 FeoB_N PF02421.18 CBZ30968.1 - 0.067 12.7 0.4 0.38 10.3 0.0 2.4 3 1 0 3 3 3 0 Ferrous iron transport protein B CUE PF02845.16 CBZ30968.1 - 0.17 11.6 0.0 0.36 10.6 0.0 1.5 1 0 0 1 1 1 0 CUE domain HBS1_N PF08938.10 CBZ30968.1 - 7.8 6.9 9.1 36 4.7 9.1 2.1 1 1 0 1 1 1 0 HBS1 N-terminus DUF2009 PF09418.10 CBZ30969.1 - 2.4e-176 587.3 0.1 2.7e-176 587.1 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2009) RNA_pol_Rpc4 PF05132.14 CBZ30970.1 - 2.4e-07 31.3 0.0 9e-07 29.4 0.0 2.1 1 1 0 1 1 1 1 RNA polymerase III RPC4 BBS1 PF14779.6 CBZ30971.1 - 2.2e-82 276.4 0.0 1e-81 274.1 0.0 2.2 3 0 0 3 3 3 1 Ciliary BBSome complex subunit 1 PHTB1_N PF14727.6 CBZ30971.1 - 0.00078 18.9 0.1 0.013 14.9 0.0 2.5 2 1 0 3 3 3 1 PTHB1 N-terminus BBS2_Mid PF14783.6 CBZ30971.1 - 0.017 15.2 0.0 7.2 6.7 0.0 3.4 3 1 0 3 3 3 0 Ciliary BBSome complex subunit 2, middle region Mcl1_mid PF12341.8 CBZ30971.1 - 0.073 12.4 0.2 3.1 7.1 0.0 2.5 1 1 2 3 3 3 0 Minichromosome loss protein, Mcl1, middle region VMA21 PF09446.10 CBZ30972.1 - 1.5e-06 28.2 5.6 2.6e-06 27.4 5.6 1.4 1 0 0 1 1 1 1 VMA21-like domain PMP22_Claudin PF00822.20 CBZ30972.1 - 0.031 14.2 0.2 0.045 13.6 0.2 1.1 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin family DUF1218 PF06749.12 CBZ30972.1 - 0.093 13.3 0.2 0.093 13.3 0.2 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1218) TMEM154 PF15102.6 CBZ30972.1 - 0.43 10.5 0.1 0.43 10.5 0.1 2.1 2 0 0 2 2 2 0 TMEM154 protein family PKD_2 PF16407.5 CBZ30973.1 - 0.03 14.5 0.0 0.054 13.7 0.0 1.3 1 0 0 1 1 1 0 PKD-like family DUF416 PF04222.12 CBZ30973.1 - 0.056 12.9 0.3 0.1 12.0 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF416) Syja_N PF02383.18 CBZ30976.1 - 5.7e-24 85.0 0.0 1.4e-23 83.7 0.0 1.6 1 1 0 1 1 1 1 SacI homology domain Methyltransf_23 PF13489.6 CBZ30978.1 - 4.2e-22 78.7 0.0 6e-22 78.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CBZ30978.1 - 6e-18 65.3 0.0 1e-17 64.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CBZ30978.1 - 7.8e-17 61.5 0.0 1.9e-16 60.2 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CBZ30978.1 - 4.2e-15 56.2 0.1 9.6e-15 55.1 0.1 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CBZ30978.1 - 3.2e-13 50.3 0.0 7.2e-13 49.1 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 CBZ30978.1 - 2e-07 30.6 0.0 6.5e-07 28.9 0.0 1.7 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_32 PF13679.6 CBZ30978.1 - 7.2e-07 29.3 0.0 1.1e-06 28.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 CBZ30978.1 - 2.7e-06 27.0 0.0 4.1e-06 26.4 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) NodS PF05401.11 CBZ30978.1 - 1.3e-05 24.9 0.3 8.4e-05 22.3 0.3 1.9 1 1 0 1 1 1 1 Nodulation protein S (NodS) Pox_MCEL PF03291.16 CBZ30978.1 - 4.4e-05 22.7 0.0 7.2e-05 22.1 0.0 1.2 1 0 0 1 1 1 1 mRNA capping enzyme MTS PF05175.14 CBZ30978.1 - 9.7e-05 22.0 0.1 0.00019 21.0 0.1 1.6 1 1 0 1 1 1 1 Methyltransferase small domain PCMT PF01135.19 CBZ30978.1 - 0.0016 18.2 0.0 0.0028 17.4 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Ubie_methyltran PF01209.18 CBZ30978.1 - 0.0017 17.8 0.0 0.0042 16.4 0.0 1.6 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family MetW PF07021.12 CBZ30978.1 - 0.0049 16.5 0.4 0.17 11.5 0.1 2.3 2 0 0 2 2 2 1 Methionine biosynthesis protein MetW TehB PF03848.14 CBZ30978.1 - 0.019 14.4 0.0 0.058 12.8 0.0 1.8 1 1 0 1 1 1 0 Tellurite resistance protein TehB TPMT PF05724.11 CBZ30978.1 - 0.041 13.5 0.0 0.065 12.9 0.0 1.3 1 0 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) FYVE PF01363.21 CBZ30979.1 - 6.2e-16 58.3 7.7 6.2e-16 58.3 7.7 2.6 2 1 0 2 2 2 1 FYVE zinc finger C1_1 PF00130.22 CBZ30979.1 - 0.046 13.6 8.4 0.11 12.4 3.4 2.3 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) C1_2 PF03107.16 CBZ30979.1 - 0.25 11.7 9.4 0.72 10.2 4.5 2.5 2 0 0 2 2 2 0 C1 domain Zn-C2H2_12 PF18112.1 CBZ30979.1 - 0.28 11.7 0.2 0.28 11.7 0.2 2.2 2 0 0 2 2 1 0 Autophagy receptor zinc finger-C2H2 domain DUF5401 PF17380.2 CBZ30979.1 - 0.48 8.4 38.0 0.65 8.0 38.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5401) DZR PF12773.7 CBZ30979.1 - 0.69 10.0 17.1 0.25 11.4 8.9 3.1 1 1 1 2 2 2 0 Double zinc ribbon zf-C3HC4_3 PF13920.6 CBZ30979.1 - 1.9 8.4 20.8 0.3 11.0 0.9 3.2 3 1 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) DUF966 PF06136.13 CBZ30979.1 - 3.2 7.4 21.1 5.2 6.7 21.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF966) DUF3584 PF12128.8 CBZ30979.1 - 5.5 4.4 43.5 7.3 4.0 43.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Hamartin PF04388.12 CBZ30979.1 - 5.7 5.5 17.3 7.9 5.0 17.3 1.2 1 0 0 1 1 1 0 Hamartin protein Rhodanese_C PF12368.8 CBZ30979.1 - 7.5 7.0 14.9 6.1 7.3 9.0 2.5 1 1 1 2 2 2 0 Rhodanase C-terminal SAS-6_N PF16531.5 CBZ30981.1 - 8.4e-19 68.0 0.0 2.1e-18 66.7 0.0 1.7 1 0 0 1 1 1 1 Centriolar protein SAS N-terminal bZIP_1 PF00170.21 CBZ30981.1 - 3.9 7.6 28.1 0.81 9.8 7.9 4.6 5 0 0 5 5 5 0 bZIP transcription factor Viral_P18 PF04521.13 CBZ30981.1 - 8.4 6.2 8.7 3.8 7.3 0.4 3.6 2 1 2 4 4 4 0 ssRNA positive strand viral 18kD cysteine rich protein PepSY_TM PF03929.16 CBZ30983.1 - 0.079 12.6 0.6 0.14 11.8 0.6 1.4 1 0 0 1 1 1 0 PepSY-associated TM region DUF4633 PF15464.6 CBZ30983.1 - 0.18 11.9 4.8 0.2 11.8 0.9 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4633) DUF4179 PF13786.6 CBZ30984.1 - 0.017 15.6 0.0 3.1 8.3 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4179) Hydrolase_6 PF13344.6 CBZ30985.1 - 2e-23 82.4 0.0 3.9e-23 81.5 0.0 1.5 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 CBZ30985.1 - 8.7e-14 51.3 0.0 2e-13 50.2 0.0 1.6 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.26 CBZ30985.1 - 0.011 16.0 0.0 7.2 6.8 0.0 2.6 2 1 0 2 2 2 0 haloacid dehalogenase-like hydrolase DUF4121 PF13497.6 CBZ30985.1 - 0.089 11.9 0.0 0.15 11.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4121) PIH1 PF08190.12 CBZ30986.1 - 2.4e-62 209.3 0.0 3.6e-62 208.7 0.0 1.3 1 0 0 1 1 1 1 PIH1 N-terminal domain PIH1_CS PF18201.1 CBZ30986.1 - 1.6e-24 86.2 0.0 3.3e-24 85.2 0.0 1.5 1 0 0 1 1 1 1 PIH1 CS-like domain KCH PF16944.5 CBZ30987.1 - 0.067 12.9 0.2 0.1 12.4 0.2 1.2 1 0 0 1 1 1 0 Fungal potassium channel PGAP1 PF07819.13 CBZ30988.1 - 6.5e-12 45.7 0.0 0.0001 22.1 0.0 3.1 2 2 0 2 2 2 2 PGAP1-like protein Abhydrolase_1 PF00561.20 CBZ30988.1 - 0.064 12.9 0.0 0.14 11.7 0.0 1.5 1 0 0 1 1 1 0 alpha/beta hydrolase fold DNA_pol_B_exo1 PF03104.19 CBZ30989.1 - 1.3e-57 195.5 0.0 2.8e-57 194.4 0.0 1.5 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain DUF1744 PF08490.12 CBZ30989.1 - 1.9e-52 178.2 0.0 3.1e-51 174.2 0.0 2.3 1 1 0 1 1 1 1 Domain of unknown function (DUF1744) DNA_pol_B PF00136.21 CBZ30989.1 - 8e-13 47.9 0.2 2.1e-10 39.9 0.2 3.0 2 1 0 2 2 2 2 DNA polymerase family B DNA_pol_B_exo2 PF10108.9 CBZ30989.1 - 7.5e-10 38.8 0.4 1.6e-08 34.5 0.4 2.5 1 1 0 1 1 1 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB RNase_H_2 PF13482.6 CBZ30989.1 - 9.1e-08 32.3 0.1 4.1e-07 30.2 0.1 2.2 1 1 0 1 1 1 1 RNase_H superfamily zf-DNA_Pol PF08996.10 CBZ30989.1 - 0.019 14.7 3.0 0.062 13.1 3.0 1.8 1 0 0 1 1 1 0 DNA Polymerase alpha zinc finger HARE-HTH PF05066.13 CBZ30989.1 - 0.16 12.4 0.1 0.41 11.1 0.1 1.7 1 0 0 1 1 1 0 HB1, ASXL, restriction endonuclease HTH domain zf-CHY PF05495.12 CBZ30989.1 - 1.9 9.0 4.8 6.9 7.2 4.7 2.1 1 1 0 1 1 1 0 CHY zinc finger zf-4CXXC_R1 PF10497.9 CBZ30989.1 - 3.6 7.9 6.4 2 8.7 1.8 2.6 2 0 0 2 2 2 0 Zinc-finger domain of monoamine-oxidase A repressor R1 zf-3CxxC PF13695.6 CBZ30990.1 - 2e-07 31.4 1.5 2.3e-07 31.2 1.5 1.2 1 0 0 1 1 1 1 Zinc-binding domain zf-3CxxC_2 PF17180.4 CBZ30990.1 - 5.8e-05 23.7 5.7 0.0001 23.0 5.7 1.5 1 1 0 1 1 1 1 Zinc-binding domain zinc_ribbon_4 PF13717.6 CBZ30990.1 - 0.0021 18.0 0.4 0.0021 18.0 0.4 2.2 2 0 0 2 2 2 1 zinc-ribbon domain HypA PF01155.19 CBZ30990.1 - 0.045 13.8 0.3 0.061 13.3 0.3 1.2 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-dskA_traR PF01258.17 CBZ30990.1 - 0.55 10.2 3.9 3.9 7.5 0.2 2.3 2 0 0 2 2 2 0 Prokaryotic dksA/traR C4-type zinc finger OrfB_Zn_ribbon PF07282.11 CBZ30990.1 - 3.2 7.7 5.8 15 5.6 0.8 2.2 1 1 1 2 2 2 0 Putative transposase DNA-binding domain HC2 PF07382.11 CBZ30991.1 - 1.7e-09 38.1 55.2 0.00016 21.8 31.7 3.6 1 1 2 3 3 3 3 Histone H1-like nucleoprotein HC2 DTHCT PF08070.11 CBZ30991.1 - 0.012 16.3 107.3 0.99 10.2 16.9 6.6 1 1 7 8 8 8 0 DTHCT (NUC029) region LisH PF08513.11 CBZ30991.1 - 0.31 11.1 0.2 0.45 10.5 0.2 1.2 1 0 0 1 1 1 0 LisH TPR_12 PF13424.6 CBZ30992.1 - 1.2e-06 28.7 11.6 0.004 17.4 0.1 4.6 3 2 1 4 4 4 4 Tetratricopeptide repeat Snf7 PF03357.21 CBZ30993.1 - 1.5e-13 50.7 16.2 1.8e-13 50.4 16.0 1.3 1 1 0 1 1 1 1 Snf7 AA_permease_2 PF13520.6 CBZ30994.1 - 1.1e-38 133.2 40.4 1.5e-38 132.8 40.4 1.1 1 0 0 1 1 1 1 Amino acid permease Mito_carr PF00153.27 CBZ30995.1 - 5.7e-30 103.1 9.1 4.3e-17 61.8 0.1 3.5 3 1 0 3 3 3 3 Mitochondrial carrier protein ArsB PF02040.15 CBZ30995.1 - 0.0089 15.4 0.3 0.013 14.8 0.3 1.2 1 0 0 1 1 1 1 Arsenical pump membrane protein zf-CCCH_2 PF14608.6 CBZ30997.1 - 0.091 13.3 6.1 0.14 12.6 6.1 1.3 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger zf-CCCH_4 PF18044.1 CBZ30997.1 - 0.093 12.6 7.0 0.35 10.7 7.0 1.9 1 1 0 1 1 1 0 CCCH-type zinc finger zf-CCCH_3 PF15663.5 CBZ30997.1 - 0.12 12.6 0.1 0.24 11.6 0.1 1.5 1 0 0 1 1 1 0 Zinc-finger containing family zf_CCCH_4 PF18345.1 CBZ30997.1 - 1.9 8.7 8.0 1.3 9.2 1.6 2.2 2 0 0 2 2 2 0 Zinc finger domain PET PF06297.14 CBZ30997.1 - 7 7.0 6.2 18 5.8 0.2 2.5 2 1 0 2 2 2 0 PET Domain LSM PF01423.22 CBZ30998.1 - 2.3e-19 68.9 0.1 2.5e-19 68.7 0.1 1.0 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 CBZ30998.1 - 0.0001 22.4 0.0 0.00011 22.3 0.0 1.1 1 0 0 1 1 1 1 Ataxin 2 SM domain LSM14 PF12701.7 CBZ30998.1 - 0.04 14.0 0.0 0.045 13.9 0.0 1.2 1 0 0 1 1 1 0 Scd6-like Sm domain CS PF04969.16 CBZ30999.1 - 6.2e-10 40.0 0.1 8.5e-10 39.5 0.1 1.2 1 0 0 1 1 1 1 CS domain ARL2_Bind_BART PF11527.8 CBZ31000.1 - 4e-08 33.3 0.8 5.4e-08 33.0 0.8 1.2 1 0 0 1 1 1 1 The ARF-like 2 binding protein BART Nic96 PF04097.14 CBZ31000.1 - 0.095 11.1 0.0 0.1 11.0 0.0 1.1 1 0 0 1 1 1 0 Nup93/Nic96 zf-ANAPC11 PF12861.7 CBZ31002.1 - 2.4e-28 98.0 10.3 2.6e-28 97.9 10.3 1.0 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.7 CBZ31002.1 - 1.8e-18 66.6 12.9 2.4e-18 66.1 12.9 1.2 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_2 PF13639.6 CBZ31002.1 - 7e-07 29.5 19.6 1.8e-05 25.0 18.6 2.5 1 1 1 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.6 CBZ31002.1 - 1.5e-06 27.9 19.0 1.3e-05 24.9 7.9 2.3 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CBZ31002.1 - 1.2e-05 25.3 11.9 2.7e-05 24.1 11.2 1.9 1 1 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 CBZ31002.1 - 5.8e-05 22.9 15.6 6.1e-05 22.8 14.3 1.8 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CBZ31002.1 - 0.00095 19.1 19.2 0.005 16.8 17.8 2.4 1 1 1 2 2 2 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 CBZ31002.1 - 0.0014 18.4 17.9 0.089 12.7 11.0 2.6 1 1 1 2 2 2 2 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 CBZ31002.1 - 0.0063 16.1 4.8 0.0063 16.1 4.8 1.8 1 1 1 2 2 2 1 Zinc-ribbon, C4HC2 type zf-RING_4 PF14570.6 CBZ31002.1 - 0.0085 15.9 18.8 0.23 11.3 11.1 2.8 1 1 1 2 2 2 1 RING/Ubox like zinc-binding domain zf-RING_11 PF17123.5 CBZ31002.1 - 0.0085 15.8 15.2 0.31 10.8 15.2 2.5 1 1 0 1 1 1 1 RING-like zinc finger zf-C3HC4_4 PF15227.6 CBZ31002.1 - 0.021 15.0 4.4 0.021 15.0 4.4 2.5 2 1 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-HIT PF04438.16 CBZ31002.1 - 0.19 11.6 10.9 0.39 10.6 6.0 2.4 2 1 0 2 2 2 0 HIT zinc finger zf-Nse PF11789.8 CBZ31002.1 - 0.37 10.7 10.1 0.53 10.1 10.1 1.3 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit PHD PF00628.29 CBZ31002.1 - 2.1 8.3 14.5 29 4.7 14.5 2.4 1 1 0 1 1 1 0 PHD-finger zf-RING-like PF08746.11 CBZ31002.1 - 9.2 6.7 17.5 1e+02 3.3 17.5 2.5 1 1 0 1 1 1 0 RING-like domain Pex14_N PF04695.13 CBZ31003.1 - 0.022 15.4 0.6 0.039 14.6 0.1 1.6 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF962 PF06127.11 CBZ31004.1 - 3.7e-21 75.0 4.8 7.9e-21 74.0 4.8 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF962) UcrQ PF02939.16 CBZ31004.1 - 0.035 14.0 0.1 0.09 12.7 0.1 1.7 1 0 0 1 1 1 0 UcrQ family RecO_C PF02565.15 CBZ31005.1 - 0.14 12.0 1.3 14 5.5 0.2 2.8 3 0 0 3 3 3 0 Recombination protein O C terminal FPL PF09758.9 CBZ31006.1 - 3.3e-52 176.4 0.6 6.1e-52 175.6 0.6 1.5 1 0 0 1 1 1 1 Uncharacterised conserved protein SET PF00856.28 CBZ31007.1 - 9.8e-33 113.9 0.5 6.2e-06 26.7 0.0 9.1 8 2 1 9 9 9 5 SET domain SAF PF08666.12 CBZ31007.1 - 5.4e-05 23.7 0.0 1.1e+02 3.5 0.0 8.6 10 1 0 10 10 10 0 SAF domain zf-HC5HC2H PF13771.6 CBZ31008.1 - 1.6e-12 47.5 4.0 1.6e-12 47.5 4.0 1.7 2 0 0 2 2 2 1 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.6 CBZ31008.1 - 2.3e-07 30.9 8.3 4.3e-07 30.1 8.3 1.4 1 0 0 1 1 1 1 PHD-zinc-finger like domain C1_2 PF03107.16 CBZ31008.1 - 0.0011 19.2 1.0 0.0034 17.7 1.0 1.9 1 0 0 1 1 1 1 C1 domain 60KD_IMP PF02096.20 CBZ31010.1 - 5.4e-05 23.2 0.0 9.3e-05 22.4 0.0 1.4 1 1 0 1 1 1 1 60Kd inner membrane protein PS_Dcarbxylase PF02666.15 CBZ31011.1 - 5.9e-39 133.7 0.0 7.1e-39 133.4 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase Collar PF07484.12 CBZ31011.1 - 0.11 12.5 0.0 3.4 7.7 0.0 2.4 2 0 0 2 2 2 0 Phage Tail Collar Domain Lebercilin PF15619.6 CBZ31012.1 - 0.00034 20.3 9.1 0.00034 20.3 9.1 5.1 5 1 0 5 5 5 2 Ciliary protein causing Leber congenital amaurosis disease BRE1 PF08647.11 CBZ31012.1 - 0.025 14.6 1.4 0.025 14.6 1.4 5.3 6 0 0 6 6 6 0 BRE1 E3 ubiquitin ligase DUF3762 PF12591.8 CBZ31012.1 - 0.065 13.5 0.1 0.21 11.8 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3762) Ima1_N PF09779.9 CBZ31012.1 - 0.077 13.9 2.9 0.24 12.3 2.9 1.8 1 0 0 1 1 1 0 Ima1 N-terminal domain TPR_MLP1_2 PF07926.12 CBZ31012.1 - 0.79 9.8 38.1 0.04 14.0 10.4 4.8 4 1 0 4 4 4 0 TPR/MLP1/MLP2-like protein Thioredoxin_4 PF13462.6 CBZ31012.1 - 1.7 8.8 7.1 0.38 10.9 0.4 2.5 2 0 0 2 2 2 0 Thioredoxin Pox_A11 PF05061.13 CBZ31012.1 - 3.3 6.9 5.7 2.8 7.2 1.7 2.6 1 1 1 2 2 2 0 Poxvirus A11 Protein DUF4407 PF14362.6 CBZ31012.1 - 9.2 5.5 28.1 7.3 5.9 1.9 3.1 1 1 0 2 2 2 0 Domain of unknown function (DUF4407) Pkinase PF00069.25 CBZ31014.1 - 5.9e-11 42.2 0.0 6.9e-10 38.7 0.0 2.2 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ31014.1 - 0.016 14.5 0.0 0.046 13.0 0.0 1.7 2 1 0 2 2 2 0 Protein tyrosine kinase DnaJ PF00226.31 CBZ31015.1 - 1.1e-13 51.0 0.1 2.2e-13 50.1 0.1 1.5 1 0 0 1 1 1 1 DnaJ domain Cgr1 PF03879.14 CBZ31016.1 - 1.3e-06 28.7 25.4 1.6e-06 28.4 25.4 1.2 1 0 0 1 1 1 1 Cgr1 family EcoRII-C PF09019.11 CBZ31016.1 - 0.014 15.5 4.4 0.019 15.0 3.9 1.5 1 1 0 1 1 1 0 EcoRII C terminal FAM178 PF14816.6 CBZ31016.1 - 0.02 13.9 5.9 0.023 13.7 5.9 1.1 1 0 0 1 1 1 0 Family of unknown function, FAM178 Med8 PF10232.9 CBZ31016.1 - 0.021 14.4 7.3 0.024 14.2 7.3 1.1 1 0 0 1 1 1 0 Mediator of RNA polymerase II transcription complex subunit 8 S1-P1_nuclease PF02265.16 CBZ31016.1 - 0.022 14.6 2.5 0.025 14.4 2.5 1.1 1 0 0 1 1 1 0 S1/P1 Nuclease AAA_11 PF13086.6 CBZ31016.1 - 0.15 11.8 13.8 0.16 11.7 13.8 1.0 1 0 0 1 1 1 0 AAA domain LPP20 PF02169.16 CBZ31016.1 - 0.76 10.2 8.1 1.2 9.5 8.1 1.4 1 1 0 1 1 1 0 LPP20 lipoprotein DUF702 PF05142.12 CBZ31016.1 - 0.87 10.1 7.4 1.1 9.7 7.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF702) DSPc PF00782.20 CBZ31017.1 - 1.1e-18 67.3 0.0 1.6e-18 66.8 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 CBZ31017.1 - 0.0067 16.0 0.0 0.0097 15.5 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase CDKN3 PF05706.12 CBZ31017.1 - 0.061 13.0 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) Y_phosphatase3 PF13350.6 CBZ31017.1 - 0.11 12.5 0.0 0.25 11.3 0.0 1.6 1 0 0 1 1 1 0 Tyrosine phosphatase family Y_phosphatase2 PF03162.13 CBZ31017.1 - 0.11 12.0 0.0 0.16 11.5 0.0 1.3 1 0 0 1 1 1 0 Tyrosine phosphatase family zf-SNAP50_C PF12251.8 CBZ31018.1 - 4.7e-38 130.9 0.3 6.9e-38 130.3 0.3 1.2 1 0 0 1 1 1 1 snRNA-activating protein of 50kDa MW C terminal Katanin_con80 PF13925.6 CBZ31019.1 - 4.3e-26 91.9 0.0 5.9e-26 91.4 0.0 1.2 1 0 0 1 1 1 1 con80 domain of Katanin WD40 PF00400.32 CBZ31019.1 - 1.4e-25 89.0 6.5 1.7e-06 28.7 0.5 5.7 5 0 0 5 5 5 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBZ31019.1 - 7.7e-13 48.6 0.0 2.6e-06 27.6 0.0 3.9 1 1 3 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 CBZ31019.1 - 0.01 15.7 0.0 6 6.7 0.0 2.6 1 1 1 2 2 2 0 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 CBZ31019.1 - 0.017 14.5 0.0 0.18 11.1 0.0 2.3 1 1 1 2 2 2 0 WD40-like domain Ge1_WD40 PF16529.5 CBZ31019.1 - 0.16 10.9 0.0 0.62 9.0 0.0 1.9 1 1 1 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein PPS_PS PF02006.16 CBZ31020.1 - 0.096 12.2 0.0 0.12 11.9 0.0 1.1 1 0 0 1 1 1 0 Phosphopantothenate/pantothenate synthetase ParcG PF10274.9 CBZ31021.1 - 1.1e-75 253.8 0.0 1.3e-75 253.5 0.0 1.1 1 0 0 1 1 1 1 Parkin co-regulated protein Kinesin PF00225.23 CBZ31022.1 - 6.8e-57 192.9 0.6 1.8e-56 191.5 0.6 1.6 1 1 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 CBZ31022.1 - 2.3e-08 34.1 0.0 4.3e-08 33.2 0.0 1.5 1 0 0 1 1 1 1 Microtubule binding DUF87 PF01935.17 CBZ31022.1 - 0.07 13.2 0.1 0.46 10.5 0.0 2.2 2 0 0 2 2 2 0 Helicase HerA, central domain AAA_16 PF13191.6 CBZ31022.1 - 0.073 13.5 0.0 0.15 12.4 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain PhoH PF02562.16 CBZ31022.1 - 0.086 12.3 0.3 3.1 7.2 0.0 2.3 2 0 0 2 2 2 0 PhoH-like protein AAA_22 PF13401.6 CBZ31022.1 - 0.3 11.4 1.1 0.71 10.1 1.1 1.8 1 1 0 1 1 1 0 AAA domain HSP70 PF00012.20 CBZ31023.1 - 1.2e-62 212.0 0.1 2.5e-62 210.9 0.1 1.5 1 1 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 CBZ31023.1 - 0.00093 18.1 0.0 0.0052 15.6 0.0 2.1 3 0 0 3 3 3 1 MreB/Mbl protein Aida_N PF08910.10 CBZ31023.1 - 0.02 15.3 1.4 0.055 13.9 1.4 1.7 1 0 0 1 1 1 0 Aida N-terminus GCV_H PF01597.19 CBZ31024.1 - 2.1e-37 127.7 1.2 2.3e-37 127.6 1.2 1.0 1 0 0 1 1 1 1 Glycine cleavage H-protein Biotin_lipoyl PF00364.22 CBZ31024.1 - 2.9e-07 30.2 0.5 5.1e-07 29.4 0.5 1.4 1 0 0 1 1 1 1 Biotin-requiring enzyme PTS_EIIA_1 PF00358.20 CBZ31024.1 - 5.3e-05 23.0 0.1 6.2e-05 22.7 0.1 1.2 1 0 0 1 1 1 1 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 RnfC_N PF13375.6 CBZ31024.1 - 0.00032 20.6 0.3 0.00041 20.2 0.3 1.2 1 0 0 1 1 1 1 RnfC Barrel sandwich hybrid domain MS_channel PF00924.18 CBZ31024.1 - 0.079 12.5 0.0 0.091 12.3 0.0 1.2 1 0 0 1 1 1 0 Mechanosensitive ion channel Peptidase_M23 PF01551.22 CBZ31024.1 - 0.093 13.0 0.5 6.5 7.0 0.2 2.2 1 1 1 2 2 2 0 Peptidase family M23 Gp_dh_N PF00044.24 CBZ31026.1 - 8.2e-17 61.4 0.0 1.8e-16 60.3 0.0 1.6 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain Gp_dh_C PF02800.20 CBZ31026.1 - 6.4e-13 48.6 0.1 9.5e-13 48.0 0.1 1.3 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain ADH_zinc_N PF00107.26 CBZ31026.1 - 0.0025 17.8 0.3 0.035 14.1 0.0 2.4 2 1 0 2 2 2 1 Zinc-binding dehydrogenase Pho88 PF10032.9 CBZ31027.1 - 0.0095 15.2 0.9 0.018 14.3 0.9 1.4 1 0 0 1 1 1 1 Phosphate transport (Pho88) Pro_isomerase PF00160.21 CBZ31028.1 - 3e-46 157.6 0.1 5.9e-46 156.6 0.1 1.5 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD TPR_2 PF07719.17 CBZ31028.1 - 6.1e-09 35.3 3.2 0.0055 16.7 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 CBZ31028.1 - 1.2e-07 31.3 2.2 0.0018 18.0 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 CBZ31028.1 - 4.9e-06 26.1 2.8 0.088 12.5 0.1 3.5 2 1 1 3 3 3 3 TPR repeat TPR_19 PF14559.6 CBZ31028.1 - 0.0001 22.7 2.9 0.064 13.8 0.2 3.0 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_9 PF13371.6 CBZ31028.1 - 0.00043 20.4 0.2 0.00097 19.2 0.2 1.6 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_6 PF13174.6 CBZ31028.1 - 0.0013 19.2 0.6 16 6.4 0.0 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.6 CBZ31028.1 - 0.0082 16.4 3.8 1.3 9.4 0.8 2.9 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 CBZ31028.1 - 0.0086 16.8 0.2 0.28 12.1 0.1 2.8 2 1 0 2 2 2 1 Tetratricopeptide repeat ANAPC3 PF12895.7 CBZ31028.1 - 0.022 14.9 2.4 0.37 11.0 1.9 2.8 1 1 1 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 DUF1586 PF07625.11 CBZ31028.1 - 0.025 14.6 0.3 0.064 13.3 0.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1586) TPR_8 PF13181.6 CBZ31028.1 - 0.03 14.5 1.1 22 5.6 0.0 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.6 CBZ31028.1 - 0.052 14.2 3.3 0.25 12.0 0.5 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat MIT PF04212.18 CBZ31028.1 - 0.06 13.4 2.9 0.067 13.3 0.3 2.1 2 0 0 2 2 2 0 MIT (microtubule interacting and transport) domain Sigma70_r3 PF04539.16 CBZ31028.1 - 0.13 12.3 0.8 0.48 10.6 0.4 2.0 2 0 0 2 2 2 0 Sigma-70 region 3 SCAMP PF04144.13 CBZ31030.1 - 4.4e-38 131.3 13.5 5.4e-38 131.0 13.5 1.0 1 0 0 1 1 1 1 SCAMP family A_deaminase PF00962.22 CBZ31031.1 - 2.2e-120 401.9 0.0 1.8e-87 293.8 0.0 3.0 2 1 0 2 2 2 2 Adenosine/AMP deaminase BRCT_2 PF16589.5 CBZ31032.1 - 9.8e-07 29.1 0.0 0.00023 21.5 0.0 2.3 2 0 0 2 2 2 2 BRCT domain, a BRCA1 C-terminus domain BRCT_3 PF18428.1 CBZ31032.1 - 0.00098 19.2 0.0 1.1 9.4 0.0 2.5 2 0 0 2 2 2 2 BRCA1 C Terminus (BRCT) domain BRCT PF00533.26 CBZ31032.1 - 0.0069 16.7 0.3 6.8 7.1 0.0 3.0 2 2 0 2 2 2 2 BRCA1 C Terminus (BRCT) domain LIG3_BRCT PF16759.5 CBZ31032.1 - 0.11 12.8 0.0 0.33 11.3 0.0 1.9 1 0 0 1 1 1 0 DNA ligase 3 BRCT domain UPF0270 PF06794.12 CBZ31032.1 - 0.16 12.1 0.0 0.32 11.1 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0270) zf-RanBP PF00641.18 CBZ31032.1 - 2 7.8 6.8 0.18 11.2 1.5 2.1 2 0 0 2 2 2 0 Zn-finger in Ran binding protein and others His_Phos_1 PF00300.22 CBZ31033.1 - 2e-11 43.9 0.0 0.00011 21.9 0.0 3.3 3 1 0 3 3 3 3 Histidine phosphatase superfamily (branch 1) Radical_SAM PF04055.21 CBZ31034.1 - 0.0076 16.6 0.0 0.075 13.4 0.0 2.2 1 1 1 2 2 2 1 Radical SAM superfamily Proteasome PF00227.26 CBZ31036.1 - 4.6e-40 137.1 0.1 6.8e-40 136.6 0.1 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 CBZ31036.1 - 1.5e-11 43.8 0.2 1.5e-11 43.8 0.2 2.0 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature DUF2358 PF10184.9 CBZ31037.1 - 0.071 13.4 0.5 0.21 11.9 0.2 1.9 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2358) Baculo_PEP_C PF04513.12 CBZ31038.1 - 0.016 15.2 1.2 0.016 15.2 1.2 9.7 2 2 9 12 12 12 0 Baculovirus polyhedron envelope protein, PEP, C terminus FAM184 PF15665.5 CBZ31038.1 - 0.051 13.3 158.9 0.051 13.3 4.2 8.9 1 1 5 7 7 7 0 Family with sequence similarity 184, A and B gag-asp_proteas PF13975.6 CBZ31038.1 - 0.55 10.8 2.6 1.2 9.7 0.4 2.8 2 0 0 2 2 2 0 gag-polyprotein putative aspartyl protease Lip_prot_lig_C PF10437.9 CBZ31038.1 - 5.4 7.1 7.5 3.4 7.7 0.4 3.5 4 0 0 4 4 4 0 Bacterial lipoate protein ligase C-terminus TPR_1 PF00515.28 CBZ31039.1 - 7.6e-15 54.0 14.5 1.5e-06 27.8 0.3 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 CBZ31039.1 - 9.6e-11 41.0 23.3 5.5e-05 23.0 0.4 4.0 3 1 1 4 4 3 3 Tetratricopeptide repeat TPR_11 PF13414.6 CBZ31039.1 - 1.9e-09 37.1 11.9 1e-08 34.7 3.2 2.8 1 1 1 2 2 2 2 TPR repeat TPR_8 PF13181.6 CBZ31039.1 - 4.3e-07 29.6 11.0 0.011 15.9 2.3 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat UPF0121 PF03661.13 CBZ31039.1 - 4.7e-06 26.2 10.5 7e-06 25.6 10.5 1.3 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0121) TPR_17 PF13431.6 CBZ31039.1 - 1.1e-05 25.4 1.1 1.1e-05 25.4 1.1 2.6 3 0 0 3 3 2 1 Tetratricopeptide repeat TPR_12 PF13424.6 CBZ31039.1 - 1.8e-05 24.9 7.7 0.00069 19.9 2.2 3.0 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.6 CBZ31039.1 - 4.4e-05 24.0 1.8 4.4e-05 24.0 1.8 3.5 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_10 PF13374.6 CBZ31039.1 - 0.0049 16.7 12.8 0.27 11.2 2.5 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat Phage_GP20 PF06810.11 CBZ31039.1 - 0.021 14.7 1.1 0.045 13.6 1.1 1.5 1 1 0 1 1 1 0 Phage minor structural protein GP20 TPR_19 PF14559.6 CBZ31039.1 - 0.027 15.0 4.5 0.21 12.1 0.8 2.7 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.6 CBZ31039.1 - 0.031 14.3 1.7 7.9 6.8 0.2 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_3 PF07720.12 CBZ31039.1 - 0.043 13.8 8.0 7.3 6.7 2.3 4.0 2 1 1 3 3 3 0 Tetratricopeptide repeat MIT PF04212.18 CBZ31039.1 - 0.19 11.8 0.3 0.19 11.8 0.3 2.9 3 0 0 3 3 3 0 MIT (microtubule interacting and transport) domain TPR_14 PF13428.6 CBZ31039.1 - 0.24 12.3 8.2 4.1 8.5 0.1 4.2 2 1 2 4 4 4 0 Tetratricopeptide repeat ANAPC3 PF12895.7 CBZ31039.1 - 0.4 10.9 8.5 0.14 12.4 5.5 1.8 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 COX14 PF14880.6 CBZ31039.1 - 0.87 9.5 8.0 0.12 12.2 1.8 2.7 2 0 0 2 2 2 0 Cytochrome oxidase c assembly Rad51 PF08423.11 CBZ31040.1 - 1.5e-123 411.0 0.0 2e-123 410.6 0.0 1.1 1 0 0 1 1 1 1 Rad51 RecA PF00154.21 CBZ31040.1 - 2.5e-13 50.1 0.2 3.4e-13 49.7 0.2 1.1 1 0 0 1 1 1 1 recA bacterial DNA recombination protein HHH_5 PF14520.6 CBZ31040.1 - 2.5e-08 34.4 0.8 8e-08 32.8 0.7 1.9 2 0 0 2 2 2 1 Helix-hairpin-helix domain ATPase PF06745.13 CBZ31040.1 - 7.9e-07 28.6 0.0 1.4e-06 27.8 0.0 1.5 1 0 0 1 1 1 1 KaiC AAA_24 PF13479.6 CBZ31040.1 - 0.14 11.8 0.0 0.25 11.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain DnaB_C PF03796.15 CBZ31040.1 - 0.15 11.4 0.0 0.29 10.4 0.0 1.5 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain MCM PF00493.23 CBZ31042.1 - 1.3e-57 194.4 0.0 2e-57 193.8 0.0 1.2 1 0 0 1 1 1 1 MCM P-loop domain MCM_lid PF17855.1 CBZ31042.1 - 6.2e-15 55.4 0.0 1.6e-14 54.0 0.0 1.7 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_OB PF17207.3 CBZ31042.1 - 1e-11 44.8 1.1 2e-11 43.8 1.1 1.4 1 0 0 1 1 1 1 MCM OB domain AAA_5 PF07728.14 CBZ31042.1 - 0.00012 22.0 0.0 0.0013 18.8 0.0 2.3 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 CBZ31042.1 - 0.00054 19.4 0.0 0.033 13.6 0.0 2.4 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 CBZ31042.1 - 0.012 15.4 0.0 0.037 13.9 0.0 1.8 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) TTL PF03133.15 CBZ31043.1 - 2.8e-76 256.4 0.0 4.8e-76 255.7 0.0 1.3 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 CBZ31043.1 - 0.0021 17.3 0.1 0.016 14.5 0.0 2.2 2 1 1 3 3 3 1 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 CBZ31043.1 - 0.08 12.2 0.0 2.6 7.2 0.0 2.1 2 0 0 2 2 2 0 Sugar-transfer associated ATP-grasp Neur_chan_memb PF02932.16 CBZ31044.1 - 0.33 11.0 3.7 0.52 10.3 3.7 1.4 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region FoP_duplication PF13865.6 CBZ31044.1 - 0.91 10.1 11.3 0.16 12.6 5.1 2.6 2 1 1 3 3 3 0 C-terminal duplication domain of Friend of PRMT1 GREB1 PF15782.5 CBZ31044.1 - 2.5 5.1 13.6 2.7 5.0 13.6 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer ALMT PF11744.8 CBZ31044.1 - 9 5.0 7.3 12 4.5 7.3 1.3 1 0 0 1 1 1 0 Aluminium activated malate transporter SUIM_assoc PF16619.5 CBZ31045.1 - 1.5e-06 28.1 3.6 0.0086 16.1 0.0 4.7 3 2 0 3 3 3 1 Unstructured region C-term to UIM in Ataxin3 zf-CCCH PF00642.24 CBZ31045.1 - 0.0012 18.7 4.6 0.0021 17.9 4.6 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 CBZ31045.1 - 0.0012 18.6 4.5 0.0019 18.0 4.5 1.3 1 0 0 1 1 1 1 CCCH-type zinc finger zf-CCCH_2 PF14608.6 CBZ31045.1 - 0.038 14.5 3.9 0.065 13.7 3.9 1.3 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger zf_CCCH_4 PF18345.1 CBZ31045.1 - 0.32 11.1 6.0 0.58 10.3 6.0 1.4 1 0 0 1 1 1 0 Zinc finger domain Glyoxalase PF00903.25 CBZ31045.1 - 3.9 7.7 5.4 2.7e+02 1.7 5.4 3.2 1 1 0 1 1 1 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Keratin_2_head PF16208.5 CBZ31046.1 - 0.98 9.5 25.8 1.6 8.9 25.8 1.4 1 0 0 1 1 1 0 Keratin type II head NPL4 PF05021.15 CBZ31047.1 - 0.17 11.2 0.1 0.27 10.6 0.1 1.2 1 0 0 1 1 1 0 NPL4 family PAP2_C PF14360.6 CBZ31048.1 - 1e-20 74.1 6.9 1e-20 74.1 6.9 2.6 3 0 0 3 3 3 1 PAP2 superfamily C-terminal PAP2 PF01569.21 CBZ31048.1 - 0.49 10.2 11.4 0.54 10.0 7.6 2.5 2 1 0 2 2 2 0 PAP2 superfamily PSP1 PF04468.12 CBZ31049.1 - 9.6e-19 67.5 1.6 1.5e-18 66.9 1.6 1.2 1 0 0 1 1 1 1 PSP1 C-terminal conserved region Leptin PF02024.15 CBZ31049.1 - 0.031 14.0 0.1 0.052 13.3 0.1 1.3 1 0 0 1 1 1 0 Leptin PE_PPE_C PF12484.8 CBZ31049.1 - 0.061 14.2 5.8 0.14 13.1 5.8 1.5 1 0 0 1 1 1 0 Polymorphic PE/PPE proteins C terminal Pkinase PF00069.25 CBZ31050.1 - 3.4e-68 229.9 0.0 4.2e-68 229.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ31050.1 - 1.9e-29 102.7 0.0 7.2e-29 100.8 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CBZ31050.1 - 9.6e-06 25.1 0.1 0.00016 21.1 0.0 2.2 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 CBZ31050.1 - 0.022 14.7 0.0 0.035 14.0 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family FTA2 PF13095.6 CBZ31050.1 - 0.024 14.3 0.0 0.043 13.4 0.0 1.6 1 1 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 Seadorna_VP7 PF07387.11 CBZ31050.1 - 0.056 12.5 0.0 0.098 11.7 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 Kdo PF06293.14 CBZ31050.1 - 0.079 12.3 0.1 0.16 11.3 0.1 1.5 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family MCD_N PF17408.2 CBZ31051.1 - 0.085 13.0 0.3 0.27 11.4 0.3 1.9 1 0 0 1 1 1 0 Malonyl-CoA decarboxylase N-terminal domain RRM_1 PF00076.22 CBZ31053.1 - 5.9e-79 259.9 4.4 9.8e-21 73.4 0.0 4.2 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP PF00658.18 CBZ31053.1 - 3.7e-21 75.1 0.3 3.2e-20 72.1 0.1 2.3 2 0 0 2 2 2 1 Poly-adenylate binding protein, unique domain RRM_5 PF13893.6 CBZ31053.1 - 3e-09 36.5 0.2 0.00036 20.1 0.0 3.2 2 1 1 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 CBZ31053.1 - 3.6e-06 27.0 1.3 0.66 10.0 0.3 4.2 4 0 0 4 4 4 2 RNA binding motif DUF4523 PF15023.6 CBZ31053.1 - 9.3e-06 25.6 0.1 0.069 13.0 0.1 3.5 2 1 1 3 3 3 1 Protein of unknown function (DUF4523) RRM_7 PF16367.5 CBZ31053.1 - 6e-05 23.1 1.0 0.14 12.3 0.1 3.6 4 2 0 4 4 4 2 RNA recognition motif Nup35_RRM_2 PF14605.6 CBZ31053.1 - 0.00016 21.6 0.5 1.1 9.3 0.1 4.1 4 0 0 4 4 4 1 Nup53/35/40-type RNA recognition motif SET_assoc PF11767.8 CBZ31053.1 - 0.021 14.4 1.9 9 6.0 0.0 3.6 4 0 0 4 4 4 0 Histone lysine methyltransferase SET associated Pkinase_C PF00433.24 CBZ31053.1 - 0.031 15.0 0.0 0.11 13.3 0.0 2.0 1 0 0 1 1 1 0 Protein kinase C terminal domain RRM_8 PF11835.8 CBZ31053.1 - 0.034 14.3 0.0 0.49 10.6 0.0 2.7 4 0 0 4 4 4 0 RRM-like domain PHM7_cyt PF14703.6 CBZ31053.1 - 0.15 12.2 0.1 26 5.0 0.0 3.5 3 1 0 3 3 3 0 Cytosolic domain of 10TM putative phosphate transporter XS PF03468.14 CBZ31053.1 - 0.21 11.9 2.6 8.6 6.7 0.2 3.1 2 1 1 3 3 3 0 XS domain bVLRF1 PF18826.1 CBZ31055.1 - 8.4e-38 129.6 0.0 1.6e-37 128.6 0.0 1.5 1 0 0 1 1 1 1 bacteroidetes VLRF1 release factor FUSC PF04632.12 CBZ31055.1 - 1.5 7.2 3.6 0.66 8.4 0.8 1.6 2 0 0 2 2 2 0 Fusaric acid resistance protein family EF-hand_6 PF13405.6 CBZ31056.1 - 0.071 13.1 1.0 0.11 12.5 0.1 1.8 2 0 0 2 2 2 0 EF-hand domain GOLGA2L5 PF15070.6 CBZ31057.1 - 0.0042 15.8 4.2 0.0054 15.5 4.2 1.1 1 0 0 1 1 1 1 Putative golgin subfamily A member 2-like protein 5 DUF1664 PF07889.12 CBZ31057.1 - 0.0088 16.1 0.3 0.016 15.2 0.3 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF1664) DUF4140 PF13600.6 CBZ31057.1 - 0.014 15.8 1.6 1.7 9.1 1.6 2.2 1 1 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) Mod_r PF07200.13 CBZ31057.1 - 0.017 15.2 4.6 0.023 14.8 4.6 1.2 1 0 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein IFT57 PF10498.9 CBZ31057.1 - 0.027 13.4 2.0 0.029 13.3 2.0 1.2 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 Laminin_II PF06009.12 CBZ31057.1 - 0.036 14.1 1.7 0.064 13.3 1.7 1.4 1 0 0 1 1 1 0 Laminin Domain II S_4TM PF18159.1 CBZ31057.1 - 0.042 13.2 2.2 0.058 12.7 2.2 1.2 1 0 0 1 1 1 0 SMODS-associating 4TM effector domain Seryl_tRNA_N PF02403.22 CBZ31057.1 - 0.045 14.0 0.6 0.067 13.4 0.6 1.3 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain Mating_N PF12731.7 CBZ31057.1 - 0.047 13.8 0.4 5.2 7.2 0.0 3.0 2 1 1 4 4 4 0 Mating-type protein beta 1 NBP1 PF08537.10 CBZ31057.1 - 0.053 12.9 0.9 0.061 12.7 0.9 1.1 1 0 0 1 1 1 0 Fungal Nap binding protein NBP1 NYD-SP28_assoc PF14775.6 CBZ31057.1 - 0.29 11.2 6.8 0.41 10.8 2.8 2.9 2 1 1 3 3 3 0 Sperm tail C-terminal domain Anti-adapt_IraP PF10796.9 CBZ31057.1 - 0.3 11.7 2.5 0.52 10.9 2.5 1.3 1 0 0 1 1 1 0 Sigma-S stabilisation anti-adaptor protein PRORP PF16953.5 CBZ31058.1 - 1.2e-28 100.3 0.5 2.1e-21 76.5 0.6 2.4 2 0 0 2 2 2 2 Protein-only RNase P PPR_long PF17177.4 CBZ31058.1 - 0.0013 18.2 0.2 0.011 15.1 0.0 2.3 2 0 0 2 2 2 1 Pentacotripeptide-repeat region of PRORP RNase_Zc3h12a PF11977.8 CBZ31058.1 - 0.054 13.3 0.0 0.84 9.4 0.0 2.3 2 0 0 2 2 2 0 Zc3h12a-like Ribonuclease NYN domain COX5A PF02284.16 CBZ31058.1 - 0.15 12.1 0.0 0.36 10.9 0.0 1.6 1 0 0 1 1 1 0 Cytochrome c oxidase subunit Va Ribosomal_L37e PF01907.19 CBZ31059.1 - 2e-20 72.7 8.1 3.2e-20 72.0 8.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L37e PseudoU_synth_2 PF00849.22 CBZ31060.1 - 2.6e-25 89.4 0.0 4.2e-25 88.7 0.0 1.4 1 0 0 1 1 1 1 RNA pseudouridylate synthase ALF PF03752.13 CBZ31060.1 - 0.042 13.8 2.2 0.14 12.2 2.2 1.9 1 0 0 1 1 1 0 Short repeats of unknown function Glycoprotein_B PF00606.18 CBZ31062.1 - 0.019 14.4 0.1 0.039 13.4 0.1 1.5 1 0 0 1 1 1 0 Herpesvirus Glycoprotein B ectodomain Methyltransf_11 PF08241.12 CBZ31063.1 - 2e-05 25.2 0.0 0.0006 20.4 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 CBZ31063.1 - 0.00033 20.5 0.0 0.00044 20.1 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CBZ31063.1 - 0.00052 20.7 0.0 0.0016 19.2 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CBZ31063.1 - 0.00087 19.9 0.0 0.053 14.2 0.0 2.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CBZ31063.1 - 0.0013 18.6 0.0 0.064 13.0 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 CBZ31063.1 - 0.17 11.2 0.0 0.4 10.0 0.0 1.5 2 0 0 2 2 2 0 ubiE/COQ5 methyltransferase family BT1 PF03092.16 CBZ31064.1 - 4.3e-213 708.3 10.9 4.9e-213 708.1 10.9 1.0 1 0 0 1 1 1 1 BT1 family MFS_1 PF07690.16 CBZ31064.1 - 0.00097 18.1 14.5 0.00097 18.1 14.5 3.6 2 1 1 3 3 3 1 Major Facilitator Superfamily AAA_28 PF13521.6 CBZ31065.1 - 0.00032 21.0 0.0 0.00047 20.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 CBZ31065.1 - 0.00074 20.1 0.0 0.0014 19.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 CBZ31065.1 - 0.00078 18.8 0.0 0.0012 18.1 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin AAA_16 PF13191.6 CBZ31065.1 - 0.0056 17.1 0.0 0.01 16.2 0.0 1.7 1 1 0 1 1 1 1 AAA ATPase domain ATPase_2 PF01637.18 CBZ31065.1 - 0.0066 16.4 0.0 0.012 15.5 0.0 1.4 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea AAA_14 PF13173.6 CBZ31065.1 - 0.0095 16.0 0.0 0.027 14.5 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 CBZ31065.1 - 0.034 14.6 0.0 0.081 13.4 0.0 1.6 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 CBZ31065.1 - 0.048 13.8 0.0 0.31 11.2 0.0 2.1 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 CBZ31065.1 - 0.057 13.8 0.0 0.11 12.9 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_25 PF13481.6 CBZ31065.1 - 0.08 12.5 0.0 0.82 9.2 0.0 2.1 2 0 0 2 2 2 0 AAA domain Rad17 PF03215.15 CBZ31065.1 - 0.084 12.8 0.0 0.16 11.9 0.0 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain SRPRB PF09439.10 CBZ31065.1 - 0.15 11.5 0.0 0.24 10.8 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 CBZ31066.1 - 0.0021 18.1 0.0 0.0036 17.4 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Peptidase_C97 PF05903.14 CBZ31067.1 - 0.056 13.3 0.0 0.12 12.3 0.0 1.4 1 0 0 1 1 1 0 PPPDE putative peptidase domain Pkinase PF00069.25 CBZ31068.1 - 1.9e-56 191.4 0.0 2.8e-56 190.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ31068.1 - 7.5e-35 120.5 0.0 1.2e-34 119.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase PH PF00169.29 CBZ31068.1 - 2.3e-11 44.1 0.0 6.4e-11 42.7 0.0 1.7 2 0 0 2 2 2 1 PH domain Kinase-like PF14531.6 CBZ31068.1 - 8.7e-07 28.5 0.0 1.6e-06 27.7 0.0 1.4 1 0 0 1 1 1 1 Kinase-like PH_11 PF15413.6 CBZ31068.1 - 0.029 14.8 0.5 0.13 12.7 0.5 2.1 1 1 0 1 1 1 0 Pleckstrin homology domain Mcp5_PH PF12814.7 CBZ31068.1 - 0.14 12.2 0.0 0.28 11.3 0.0 1.4 1 0 0 1 1 1 0 Meiotic cell cortex C-terminal pleckstrin homology Haspin_kinase PF12330.8 CBZ31068.1 - 0.16 10.9 0.0 0.25 10.3 0.0 1.4 1 0 0 1 1 1 0 Haspin like kinase domain zf-CCCH PF00642.24 CBZ31069.1 - 3e-06 27.0 5.6 8e-06 25.6 0.1 2.4 2 0 0 2 2 2 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 CBZ31069.1 - 8.9e-06 25.6 5.7 0.00048 20.1 0.2 2.7 2 1 0 2 2 2 2 Zinc finger domain zf-CCCH_3 PF15663.5 CBZ31069.1 - 0.00061 20.0 0.9 0.0014 18.8 0.9 1.6 1 0 0 1 1 1 1 Zinc-finger containing family zf-CCCH_2 PF14608.6 CBZ31069.1 - 0.01 16.3 9.5 0.38 11.3 0.4 2.4 2 0 0 2 2 2 0 RNA-binding, Nab2-type zinc finger zf-CCCH_4 PF18044.1 CBZ31069.1 - 0.28 11.0 5.3 1.6 8.6 0.2 3.0 2 1 0 2 2 2 0 CCCH-type zinc finger Torus PF16131.5 CBZ31069.1 - 0.88 10.3 4.8 7.1 7.4 1.0 2.3 1 1 1 2 2 2 0 Torus domain MMR_HSR1 PF01926.23 CBZ31070.1 - 1e-12 48.1 0.0 1.7e-11 44.2 0.0 2.2 2 0 0 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 CBZ31070.1 - 8.5e-07 29.0 0.0 7.3e-06 26.0 0.0 2.1 1 1 0 1 1 1 1 RsgA GTPase AAA_22 PF13401.6 CBZ31070.1 - 0.0043 17.3 0.0 0.01 16.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain FeoB_N PF02421.18 CBZ31070.1 - 0.021 14.4 0.1 0.049 13.2 0.0 1.6 2 0 0 2 2 2 0 Ferrous iron transport protein B Dynamin_N PF00350.23 CBZ31070.1 - 0.037 14.1 0.6 3.5 7.7 0.0 2.8 2 1 1 3 3 3 0 Dynamin family Septin PF00735.18 CBZ31070.1 - 0.12 11.6 0.0 0.22 10.7 0.0 1.3 1 0 0 1 1 1 0 Septin AAA_16 PF13191.6 CBZ31070.1 - 0.15 12.5 0.0 0.46 10.9 0.0 1.8 2 0 0 2 2 2 0 AAA ATPase domain Dyp_perox PF04261.12 CBZ31071.1 - 0.044 12.8 0.5 0.085 11.8 0.1 1.5 1 1 0 1 1 1 0 Dyp-type peroxidase family DivIVA PF05103.13 CBZ31071.1 - 0.19 11.8 0.1 0.19 11.8 0.1 3.3 3 1 0 3 3 3 0 DivIVA protein CEP63 PF17045.5 CBZ31071.1 - 0.31 10.9 17.6 0.92 9.4 2.3 3.7 2 1 2 4 4 4 0 Centrosomal protein of 63 kDa RRP36 PF06102.12 CBZ31071.1 - 0.58 10.1 4.5 0.25 11.3 1.8 1.8 2 0 0 2 2 2 0 rRNA biogenesis protein RRP36 DUF4407 PF14362.6 CBZ31071.1 - 4.6 6.5 14.3 1.3 8.3 11.4 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Methyltransf_4 PF02390.17 CBZ31072.1 - 6.2e-37 126.7 0.0 7.7e-37 126.4 0.0 1.1 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_31 PF13847.6 CBZ31072.1 - 0.00029 20.7 0.0 0.00068 19.4 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 CBZ31072.1 - 0.00082 20.0 0.0 0.0022 18.6 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 CBZ31072.1 - 0.0049 17.6 0.0 0.011 16.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Transpos_assoc PF13963.6 CBZ31072.1 - 0.089 13.1 0.0 0.28 11.5 0.0 1.9 2 0 0 2 2 2 0 Transposase-associated domain DOT1 PF08123.13 CBZ31072.1 - 0.12 11.9 0.0 0.18 11.3 0.0 1.3 1 0 0 1 1 1 0 Histone methylation protein DOT1 ALG11_N PF15924.5 CBZ31074.1 - 7.3e-60 202.6 0.0 1e-59 202.1 0.0 1.1 1 0 0 1 1 1 1 ALG11 mannosyltransferase N-terminus Glycos_transf_1 PF00534.20 CBZ31074.1 - 1e-21 77.3 0.0 1.5e-21 76.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 CBZ31074.1 - 5e-11 43.2 0.3 9e-11 42.3 0.3 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 CBZ31074.1 - 0.0059 17.0 0.0 0.014 15.7 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferases group 1 HALZ PF02183.18 CBZ31075.1 - 4.3e-06 26.8 1.1 7.9e-06 26.0 1.1 1.4 1 0 0 1 1 1 1 Homeobox associated leucine zipper Fungal_TACC PF12709.7 CBZ31075.1 - 0.0026 18.2 0.3 0.0033 17.8 0.2 1.4 1 1 0 1 1 1 1 Fungal Transforming acidic coiled-coil (TACC) proteins Prp19 PF08606.11 CBZ31075.1 - 0.0058 16.6 0.3 0.2 11.7 0.1 2.1 2 0 0 2 2 2 1 Prp19/Pso4-like DUF1640 PF07798.11 CBZ31075.1 - 0.0068 16.5 0.2 0.0079 16.3 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1640) DivIC PF04977.15 CBZ31075.1 - 0.016 15.0 2.8 0.019 14.8 0.4 1.9 2 0 0 2 2 2 0 Septum formation initiator ZapB PF06005.12 CBZ31075.1 - 0.052 14.0 0.6 0.052 14.0 0.6 1.8 2 1 0 2 2 2 0 Cell division protein ZapB Dpy-30 PF05186.13 CBZ31075.1 - 0.06 13.1 0.2 0.16 11.7 0.2 1.7 1 1 0 1 1 1 0 Dpy-30 motif bZIP_2 PF07716.15 CBZ31075.1 - 0.079 13.1 1.0 0.079 13.1 1.0 1.8 2 0 0 2 2 2 0 Basic region leucine zipper AvrPto PF11592.8 CBZ31075.1 - 0.094 12.8 0.0 0.11 12.6 0.0 1.1 1 0 0 1 1 1 0 Central core of the bacterial effector protein AvrPto WD40 PF00400.32 CBZ31076.1 - 4e-09 36.9 5.1 0.0057 17.5 0.1 3.9 3 0 0 3 3 3 3 WD domain, G-beta repeat 7tm_6 PF02949.20 CBZ31079.1 - 0.086 11.9 0.9 0.14 11.2 0.9 1.2 1 0 0 1 1 1 0 7tm Odorant receptor MMR_HSR1_Xtn PF16897.5 CBZ31080.1 - 3.9e-36 123.3 0.4 7.4e-36 122.4 0.4 1.4 1 0 0 1 1 1 1 C-terminal region of MMR_HSR1 domain TGS PF02824.21 CBZ31080.1 - 6.9e-23 80.5 0.0 1.5e-22 79.4 0.0 1.6 1 0 0 1 1 1 1 TGS domain MMR_HSR1 PF01926.23 CBZ31080.1 - 5e-19 68.5 0.0 1.1e-18 67.3 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 CBZ31080.1 - 8.6e-10 38.3 0.0 1.6e-09 37.5 0.0 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.23 CBZ31080.1 - 0.00054 20.0 0.2 0.16 12.0 0.0 2.5 1 1 1 2 2 2 2 Dynamin family Roc PF08477.13 CBZ31080.1 - 0.0078 16.4 0.3 0.62 10.3 0.0 3.3 1 1 2 3 3 3 1 Ras of Complex, Roc, domain of DAPkinase AIG1 PF04548.16 CBZ31080.1 - 0.055 12.8 0.0 0.095 12.0 0.0 1.4 1 0 0 1 1 1 0 AIG1 family SAC3_GANP PF03399.16 CBZ31081.1 - 1.7e-11 44.0 1.2 6.9e-10 38.8 1.2 2.2 1 1 0 1 1 1 1 SAC3/GANP family FMN_dh PF01070.18 CBZ31082.1 - 4.8e-31 108.1 0.1 6.8e-20 71.4 0.2 2.2 2 0 0 2 2 2 2 FMN-dependent dehydrogenase IMPDH PF00478.25 CBZ31082.1 - 1.6e-07 30.6 0.4 0.0017 17.4 0.1 2.3 1 1 1 2 2 2 2 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.17 CBZ31082.1 - 5.5e-05 22.5 1.5 0.00042 19.6 1.5 2.1 1 1 0 1 1 1 1 Conserved region in glutamate synthase NMO PF03060.15 CBZ31082.1 - 0.033 13.6 0.2 0.065 12.6 0.2 1.4 1 0 0 1 1 1 0 Nitronate monooxygenase His_biosynth PF00977.21 CBZ31082.1 - 0.26 10.7 2.1 1.3 8.4 0.1 2.4 2 1 1 3 3 3 0 Histidine biosynthesis protein Ank_2 PF12796.7 CBZ31083.1 - 3.9e-10 40.2 0.0 1.1e-09 38.8 0.0 1.7 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Dynein_heavy PF03028.15 CBZ31083.1 - 1e-08 35.3 0.0 1.8e-08 34.5 0.0 1.4 1 0 0 1 1 1 1 Dynein heavy chain region D6 P-loop domain Ank_4 PF13637.6 CBZ31083.1 - 2.1e-06 28.2 0.0 0.023 15.3 0.0 3.3 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 CBZ31083.1 - 2.6e-05 24.4 0.0 0.00057 20.2 0.0 2.4 2 0 0 2 2 2 1 Ankyrin repeat Ank_3 PF13606.6 CBZ31083.1 - 0.00033 20.9 0.0 0.12 13.0 0.0 3.4 3 0 0 3 3 3 1 Ankyrin repeat Aa_trans PF01490.18 CBZ31084.1 - 1e-56 192.4 32.3 1.3e-56 192.1 32.3 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Aa_trans PF01490.18 CBZ31085.1 - 7.1e-51 173.2 34.1 7.9e-51 173.0 34.1 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 CBZ31085.1 - 3.4e-06 26.4 20.6 1.1e-05 24.7 19.5 2.2 1 1 1 2 2 2 2 Tryptophan/tyrosine permease family DAGK_acc PF00609.19 CBZ31086.1 - 8.4e-37 127.0 0.0 1.2e-36 126.5 0.0 1.2 1 0 0 1 1 1 1 Diacylglycerol kinase accessory domain DAGK_cat PF00781.24 CBZ31086.1 - 2.2e-12 46.7 0.0 3.4e-12 46.1 0.0 1.3 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain NAD_kinase PF01513.21 CBZ31086.1 - 0.075 12.2 0.0 0.11 11.6 0.0 1.2 1 0 0 1 1 1 0 ATP-NAD kinase HECT PF00632.25 CBZ31088.1 - 4.5e-36 124.9 0.2 1.1e-35 123.7 0.2 1.6 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) SPRY PF00622.28 CBZ31088.1 - 1.9e-19 69.9 0.2 4.1e-07 30.1 0.0 5.3 5 0 0 5 5 5 3 SPRY domain Amastin PF07344.11 CBZ40909.1 - 1.5e-33 115.8 12.4 1.7e-33 115.6 12.4 1.0 1 0 0 1 1 1 1 Amastin surface glycoprotein HisKA_7TM PF16927.5 CBZ40909.1 - 0.0057 16.7 2.7 0.0063 16.6 2.7 1.1 1 0 0 1 1 1 1 N-terminal 7TM region of histidine kinase DUF805 PF05656.14 CBZ40909.1 - 0.0085 16.5 5.4 0.012 16.0 5.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF805) MIG-14_Wnt-bd PF06664.12 CBZ40909.1 - 0.18 11.0 6.0 0.71 9.0 5.6 1.8 1 1 1 2 2 2 0 Wnt-binding factor required for Wnt secretion Claudin_2 PF13903.6 CBZ40909.1 - 0.58 9.9 12.5 1 9.1 12.4 1.5 1 1 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction Inhibitor_I29 PF08246.12 CBZ40910.1 - 1.4e-11 44.6 0.5 1.6e-11 44.4 0.5 1.1 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1 PF00112.23 CBZ40911.1 - 4.7e-71 239.3 1.0 6.1e-71 239.0 1.0 1.1 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.12 CBZ40911.1 - 8.8e-12 45.3 0.9 1.4e-11 44.7 0.9 1.3 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.15 CBZ40911.1 - 1e-06 27.9 0.2 6.5e-05 21.9 0.1 2.1 2 0 0 2 2 2 2 Peptidase C1-like family Amastin PF07344.11 CBZ40912.1 - 2.3e-46 157.5 8.5 2.7e-46 157.2 8.5 1.0 1 0 0 1 1 1 1 Amastin surface glycoprotein PMP22_Claudin PF00822.20 CBZ40912.1 - 0.039 13.8 4.7 0.05 13.5 4.7 1.3 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin family DUF2165 PF09933.9 CBZ40912.1 - 0.12 12.4 5.5 0.039 14.0 1.8 1.9 2 0 0 2 2 2 0 Predicted small integral membrane protein (DUF2165) DUF1218 PF06749.12 CBZ40912.1 - 5.2 7.7 15.4 11 6.6 0.9 3.3 2 1 1 3 3 3 0 Protein of unknown function (DUF1218) FA_desaturase PF00487.24 CBZ40912.1 - 6.2 6.6 7.8 6.2 6.6 6.5 1.7 1 1 0 1 1 1 0 Fatty acid desaturase TrbC PF04956.13 CBZ40912.1 - 7.7 6.8 11.0 0.33 11.2 0.2 2.6 2 1 1 3 3 3 0 TrbC/VIRB2 family Amastin PF07344.11 CBZ40913.1 - 2.5e-53 180.1 10.8 3.3e-53 179.7 10.8 1.1 1 0 0 1 1 1 1 Amastin surface glycoprotein Nodulin-like PF06813.13 CBZ40914.1 - 4.1e-08 33.0 12.6 4.1e-08 33.0 12.6 2.5 2 1 0 2 2 2 1 Nodulin-like MotA_ExbB PF01618.16 CBZ40914.1 - 0.13 12.0 0.0 0.37 10.6 0.0 1.7 1 0 0 1 1 1 0 MotA/TolQ/ExbB proton channel family DUF4872 PF16169.5 CBZ40915.1 - 0.071 12.9 0.4 0.12 12.1 0.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4872) Ribosomal_L28e PF01778.17 CBZ40916.1 - 1.1e-18 68.1 0.6 2.2e-18 67.1 0.1 1.6 1 1 0 1 1 1 1 Ribosomal L28e protein family bPH_6 PF10756.9 CBZ40916.1 - 0.0076 16.3 0.7 0.012 15.7 0.7 1.3 1 0 0 1 1 1 1 Bacterial PH domain E1-N PF14463.6 CBZ40917.1 - 1.8e-05 24.6 0.6 18 5.1 0.0 4.7 4 0 0 4 4 4 4 E1 N-terminal domain PSD2 PF07624.11 CBZ40917.1 - 0.0004 20.1 0.2 58 3.6 0.0 4.2 4 0 0 4 4 4 4 Protein of unknown function (DUF1585) HNH_repeat PF18780.1 CBZ40917.1 - 2 8.3 8.8 1.1e+02 2.8 0.1 4.3 4 0 0 4 4 4 0 Homing endonuclease repeat RMI2 PF16100.5 CBZ40918.1 - 0.018 14.8 0.3 0.049 13.5 0.0 1.8 2 0 0 2 2 2 0 RecQ-mediated genome instability protein 2 Mei5_like PF17021.5 CBZ40918.1 - 0.072 13.1 0.0 0.12 12.4 0.0 1.3 1 0 0 1 1 1 0 Putative double-strand recombination repair-like LRR_8 PF13855.6 CBZ40922.1 - 9.2e-09 34.9 0.0 0.00091 19.0 0.0 2.8 2 1 0 2 2 2 2 Leucine rich repeat AAA_16 PF13191.6 CBZ40923.1 - 0.0033 17.8 0.1 0.0082 16.5 0.1 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_14 PF13173.6 CBZ40923.1 - 0.058 13.4 0.0 0.083 12.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain Peptidase_C2 PF00648.21 CBZ40924.1 - 3.8e-61 206.7 0.0 4.8e-61 206.4 0.0 1.1 1 0 0 1 1 1 1 Calpain family cysteine protease Calpain_III PF01067.22 CBZ40924.1 - 0.033 14.5 0.0 0.074 13.3 0.0 1.6 1 0 0 1 1 1 0 Calpain large subunit, domain III Glyco_hydro_32N PF00251.20 CBZ40925.1 - 4.6e-86 289.2 0.2 7.1e-86 288.5 0.2 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 N-terminal domain Glyco_hydro_32C PF08244.12 CBZ40925.1 - 8.8e-18 64.8 0.0 1.3e-17 64.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 C terminal Glyco_hydro_32N PF00251.20 CBZ40926.1 - 2.8e-82 276.7 0.1 4.5e-82 276.0 0.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 N-terminal domain Glyco_hydro_32C PF08244.12 CBZ40926.1 - 4.5e-21 75.5 0.0 6.7e-21 74.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 C terminal Glyco_hydro_43 PF04616.14 CBZ40926.1 - 1.5e-06 27.8 0.7 2.3e-06 27.2 0.7 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 Amastin PF07344.11 CBZ40927.1 - 4.7e-52 175.9 6.5 5.6e-52 175.7 6.5 1.0 1 0 0 1 1 1 1 Amastin surface glycoprotein DUF4407 PF14362.6 CBZ40927.1 - 2.9 7.2 4.3 4.6 6.5 4.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF2417 PF10329.9 CBZ40927.1 - 3.1 7.2 6.0 0.69 9.3 0.4 2.2 2 1 0 2 2 2 0 Region of unknown function (DUF2417) Amastin PF07344.11 CBZ40928.1 - 5e-47 159.6 10.6 6e-47 159.4 10.6 1.1 1 0 0 1 1 1 1 Amastin surface glycoprotein DUF805 PF05656.14 CBZ40928.1 - 0.19 12.1 9.9 0.027 14.9 5.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF805) RMI2 PF16100.5 CBZ40929.1 - 0.0094 15.8 0.1 0.024 14.4 0.0 1.6 2 0 0 2 2 2 1 RecQ-mediated genome instability protein 2 Mei5_like PF17021.5 CBZ40929.1 - 0.041 13.9 0.0 0.071 13.1 0.0 1.3 1 0 0 1 1 1 0 Putative double-strand recombination repair-like Amastin PF07344.11 CBZ40930.1 - 6e-50 169.1 13.4 7.6e-50 168.8 13.4 1.1 1 0 0 1 1 1 1 Amastin surface glycoprotein Phage_holin_3_6 PF07332.11 CBZ40930.1 - 0.014 15.4 0.5 0.014 15.4 0.5 2.4 3 0 0 3 3 3 0 Putative Actinobacterial Holin-X, holin superfamily III RMI2 PF16100.5 CBZ40931.1 - 0.021 14.6 0.0 0.066 13.0 0.0 1.7 1 0 0 1 1 1 0 RecQ-mediated genome instability protein 2 Mei5_like PF17021.5 CBZ40931.1 - 0.068 13.2 0.0 0.12 12.4 0.0 1.3 1 0 0 1 1 1 0 Putative double-strand recombination repair-like YajC PF02699.15 CBZ40931.1 - 0.079 12.8 0.5 2.9 7.9 0.1 2.7 3 0 0 3 3 3 0 Preprotein translocase subunit Aa_trans PF01490.18 CBZ40932.1 - 1e-59 202.3 25.3 1.2e-59 202.0 25.3 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 CBZ40932.1 - 1.3e-10 40.9 7.0 2.9e-10 39.7 7.0 1.5 1 0 0 1 1 1 1 Tryptophan/tyrosine permease family DUF4231 PF14015.6 CBZ40932.1 - 0.059 13.8 6.6 1.4 9.4 0.3 3.7 3 1 1 4 4 4 0 Protein of unknown function (DUF4231) DAGAT PF03982.13 CBZ40933.1 - 9.3e-22 77.3 0.1 1.7e-21 76.4 0.0 1.4 2 0 0 2 2 2 1 Diacylglycerol acyltransferase Acyltransferase PF01553.21 CBZ40933.1 - 0.028 14.0 0.0 0.057 13.1 0.0 1.4 1 0 0 1 1 1 0 Acyltransferase MitoNEET_N PF10660.9 CBZ40933.1 - 0.088 12.9 0.3 0.44 10.6 0.2 2.0 2 0 0 2 2 2 0 Iron-containing outer mitochondrial membrane protein N-terminus Amastin PF07344.11 CBZ40934.1 - 1.5e-22 80.1 8.8 1.7e-22 79.9 8.8 1.0 1 0 0 1 1 1 1 Amastin surface glycoprotein CrgA PF06781.12 CBZ40934.1 - 0.028 14.5 2.1 0.028 14.5 2.1 2.0 2 0 0 2 2 2 0 Cell division protein CrgA Phage_holin_3_6 PF07332.11 CBZ40934.1 - 4.8 7.3 10.4 0.2 11.7 3.6 1.9 1 1 1 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III Amastin PF07344.11 CBZ40935.1 - 3.1e-50 170.0 9.3 3.8e-50 169.8 9.3 1.1 1 0 0 1 1 1 1 Amastin surface glycoprotein DUF4407 PF14362.6 CBZ40935.1 - 5.5 6.3 6.2 9.5 5.5 6.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF1935 PF09149.10 CBZ40936.1 - 9.2e-19 67.7 0.0 2.5e-18 66.3 0.0 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF1935) HK97-gp10_like PF04883.12 CBZ40938.1 - 0.074 14.0 0.4 31 5.7 0.1 2.7 2 0 0 2 2 2 0 Bacteriophage HK97-gp10, putative tail-component LRR_8 PF13855.6 CBZ40939.1 - 3.3e-07 30.0 0.0 0.00018 21.2 0.0 2.4 1 1 2 3 3 3 3 Leucine rich repeat LRR_4 PF12799.7 CBZ40939.1 - 0.00039 20.7 0.0 0.26 11.8 0.0 3.0 3 0 0 3 3 3 1 Leucine Rich repeats (2 copies) LRRNT_2 PF08263.12 CBZ40939.1 - 0.037 14.3 0.4 0.037 14.3 0.4 3.5 4 0 0 4 4 4 0 Leucine rich repeat N-terminal domain Endomucin PF07010.12 CBZ40939.1 - 0.96 9.4 34.6 2.2 8.2 34.6 1.5 1 0 0 1 1 1 0 Endomucin Atrophin-1 PF03154.15 CBZ40939.1 - 3.5 5.8 20.5 4.8 5.3 20.5 1.1 1 0 0 1 1 1 0 Atrophin-1 family PRCC PF10253.9 CBZ40939.1 - 5.1 7.8 11.3 7.8 7.2 11.3 1.3 1 0 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting SOG2 PF10428.9 CBZ40939.1 - 9.5 5.3 19.0 13 4.8 19.0 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein Peptidase_C2 PF00648.21 CBZ40940.1 - 1.9e-49 168.3 0.0 2.6e-49 167.8 0.0 1.1 1 0 0 1 1 1 1 Calpain family cysteine protease DUF1935 PF09149.10 CBZ40940.1 - 9.4e-19 67.7 0.0 2.4e-18 66.4 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1935) Peptidase_C2 PF00648.21 CBZ40941.1 - 1.3e-34 119.6 0.0 1.9e-34 119.1 0.0 1.3 1 0 0 1 1 1 1 Calpain family cysteine protease DUF1935 PF09149.10 CBZ40941.1 - 1.8e-23 82.9 0.0 3.2e-23 82.1 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1935) YkyB PF14177.6 CBZ40941.1 - 0.15 12.4 0.0 0.31 11.3 0.0 1.4 1 0 0 1 1 1 0 YkyB-like protein Peptidase_C2 PF00648.21 CBZ40942.1 - 2.9e-64 217.0 0.0 3.8e-64 216.6 0.0 1.2 1 0 0 1 1 1 1 Calpain family cysteine protease DUF1935 PF09149.10 CBZ40942.1 - 2e-17 63.5 0.2 4e-17 62.5 0.2 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1935) Calpain_III PF01067.22 CBZ40942.1 - 0.014 15.6 0.0 0.036 14.3 0.0 1.7 1 0 0 1 1 1 0 Calpain large subunit, domain III LRR_4 PF12799.7 CBZ40944.1 - 5.1e-15 55.3 12.4 0.0056 17.1 0.1 6.5 5 1 4 9 9 9 6 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CBZ40944.1 - 6.2e-14 51.5 8.4 1.2e-05 24.9 0.6 4.9 2 2 5 7 7 7 7 Leucine rich repeat LRR_1 PF00560.33 CBZ40944.1 - 0.00015 21.9 11.0 1.3 9.8 0.1 7.4 7 0 0 7 7 7 2 Leucine Rich Repeat DUF3338 PF11819.8 CBZ40944.1 - 0.039 13.9 0.0 15 5.6 0.0 3.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3338) LRR_6 PF13516.6 CBZ40944.1 - 0.092 12.9 10.6 0.53 10.5 0.1 4.5 4 0 0 4 4 4 0 Leucine Rich repeat FA_desaturase PF00487.24 CBZ40947.1 - 1.4e-22 80.7 25.3 1.9e-22 80.3 25.3 1.1 1 0 0 1 1 1 1 Fatty acid desaturase Lipid_DES PF08557.10 CBZ40947.1 - 0.002 17.6 0.2 0.0035 16.8 0.2 1.4 1 0 0 1 1 1 1 Sphingolipid Delta4-desaturase (DES) ABC_tran PF00005.27 CBZ40948.1 - 2.1e-25 89.8 0.0 6.3e-25 88.3 0.0 1.7 2 0 0 2 2 2 1 ABC transporter AAA_21 PF13304.6 CBZ40948.1 - 1.7e-09 37.9 0.1 2e-06 27.9 0.0 2.6 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system Zeta_toxin PF06414.12 CBZ40948.1 - 0.0009 18.6 0.0 0.44 9.8 0.0 2.5 2 0 0 2 2 2 2 Zeta toxin SRP54 PF00448.22 CBZ40948.1 - 0.048 13.3 0.0 0.1 12.2 0.0 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_15 PF13175.6 CBZ40948.1 - 0.063 13.0 0.1 12 5.4 0.0 2.6 3 0 0 3 3 3 0 AAA ATPase domain AAA_23 PF13476.6 CBZ40948.1 - 0.077 13.5 3.0 0.17 12.4 0.1 2.1 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 CBZ40948.1 - 0.089 13.2 0.5 0.33 11.4 0.1 2.4 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) LRR_8 PF13855.6 CBZ40949.1 - 1.7e-11 43.7 7.6 2.4e-07 30.4 1.7 3.6 2 1 2 4 4 4 4 Leucine rich repeat LRR_4 PF12799.7 CBZ40949.1 - 4.4e-08 33.3 6.3 0.0021 18.4 1.6 4.5 3 1 4 7 7 7 5 Leucine Rich repeats (2 copies) Amastin PF07344.11 CBZ40950.1 - 1.8e-52 177.3 7.4 2.2e-52 177.0 7.4 1.1 1 0 0 1 1 1 1 Amastin surface glycoprotein DUF4525 PF15027.6 CBZ40950.1 - 2.1 8.1 3.3 11 5.8 0.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4525) Claudin_2 PF13903.6 CBZ40950.1 - 2.4 7.9 10.4 0.7 9.6 5.2 2.4 1 1 1 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction DUF4407 PF14362.6 CBZ40950.1 - 3.9 6.7 6.6 6.6 6.0 6.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Peptidase_C1 PF00112.23 CBZ40951.1 - 1.8e-70 237.4 0.9 2.3e-70 237.1 0.9 1.1 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.12 CBZ40951.1 - 7.8e-12 45.5 0.9 1.2e-11 44.8 0.9 1.3 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.15 CBZ40951.1 - 6.9e-06 25.1 0.6 0.00099 18.0 0.2 2.1 2 0 0 2 2 2 2 Peptidase C1-like family Peptidase_C1 PF00112.23 CBZ40952.1 - 1.6e-32 113.4 0.1 1.6e-32 113.4 0.1 1.9 2 0 0 2 2 2 1 Papain family cysteine protease DUF3586 PF12131.8 CBZ40952.1 - 8.4e-21 74.0 7.4 8.4e-21 74.0 7.4 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF3586) Peptidase_C1_2 PF03051.15 CBZ40952.1 - 0.00022 20.2 0.1 0.00027 19.9 0.1 1.1 1 0 0 1 1 1 1 Peptidase C1-like family Amastin PF07344.11 CBZ40953.1 - 5.6e-20 71.8 0.1 6.5e-20 71.6 0.1 1.1 1 0 0 1 1 1 1 Amastin surface glycoprotein Amastin PF07344.11 CBZ40954.1 - 3.4e-38 130.9 4.2 3.8e-38 130.8 4.2 1.0 1 0 0 1 1 1 1 Amastin surface glycoprotein DUF2165 PF09933.9 CBZ40954.1 - 0.14 12.1 6.5 0.047 13.7 3.0 1.8 2 0 0 2 2 2 0 Predicted small integral membrane protein (DUF2165) Phage_holin_3_6 PF07332.11 CBZ40954.1 - 2.1 8.4 9.4 0.49 10.4 4.6 1.9 2 0 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III DUF2721 PF11026.8 CBZ40954.1 - 5.5 6.9 10.4 0.57 10.1 6.1 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2721) Ribosomal_S3Ae PF01015.18 CBZ40955.1 - 3.3e-68 229.3 3.9 4e-68 229.0 3.9 1.0 1 0 0 1 1 1 1 Ribosomal S3Ae family DNA_pol3_delt_C PF14840.6 CBZ40955.1 - 0.076 13.3 2.4 0.12 12.7 2.0 1.5 1 1 0 1 1 1 0 Processivity clamp loader gamma complex DNA pol III C-term Ribosomal_S3Ae PF01015.18 CBZ40956.1 - 3.3e-68 229.3 3.9 4e-68 229.0 3.9 1.0 1 0 0 1 1 1 1 Ribosomal S3Ae family DNA_pol3_delt_C PF14840.6 CBZ40956.1 - 0.076 13.3 2.4 0.12 12.7 2.0 1.5 1 1 0 1 1 1 0 Processivity clamp loader gamma complex DNA pol III C-term MFS_1 PF07690.16 CBZ40957.1 - 2.3e-24 86.0 28.5 9.2e-19 67.6 17.2 2.4 2 1 0 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 CBZ40957.1 - 1.5e-10 40.5 3.0 0.0002 20.3 2.9 2.8 1 1 1 2 2 2 2 MFS_1 like family Sugar_tr PF00083.24 CBZ40957.1 - 2e-05 23.7 22.0 2.2e-05 23.5 8.3 2.9 2 1 0 3 3 3 2 Sugar (and other) transporter Amastin PF07344.11 CBZ40958.1 - 1.9e-50 170.7 9.3 2.2e-50 170.5 9.3 1.0 1 0 0 1 1 1 1 Amastin surface glycoprotein Amastin PF07344.11 CBZ40960.1 - 7.5e-54 181.8 10.4 8.9e-54 181.5 10.4 1.0 1 0 0 1 1 1 1 Amastin surface glycoprotein PMP22_Claudin PF00822.20 CBZ40960.1 - 0.0099 15.8 8.0 0.014 15.3 8.0 1.2 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family DUF1218 PF06749.12 CBZ40960.1 - 0.39 11.3 17.4 2.2 8.8 0.0 3.9 1 1 2 3 3 3 0 Protein of unknown function (DUF1218) Claudin_2 PF13903.6 CBZ40960.1 - 5.9 6.6 19.2 0.28 10.9 10.8 2.4 1 1 1 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction RMI2 PF16100.5 CBZ40961.1 - 0.0092 15.8 0.0 0.013 15.3 0.0 1.2 1 0 0 1 1 1 1 RecQ-mediated genome instability protein 2 DUF4819 PF16090.5 CBZ40961.1 - 0.18 11.9 0.0 0.37 10.9 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4819) Amastin PF07344.11 CBZ40962.1 - 5e-47 159.6 10.6 6e-47 159.4 10.6 1.1 1 0 0 1 1 1 1 Amastin surface glycoprotein DUF805 PF05656.14 CBZ40962.1 - 0.19 12.1 9.9 0.027 14.9 5.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF805) Nop52 PF05997.12 CBZ40963.1 - 0.11 12.3 0.0 0.19 11.5 0.0 1.4 1 0 0 1 1 1 0 Nucleolar protein,Nop52 Stealth_CR2 PF11380.8 CBZ40964.1 - 4.2e-17 62.3 0.1 6.1e-15 55.3 0.1 2.4 1 1 0 1 1 1 1 Stealth protein CR2, conserved region 2 Stealth_CR3 PF17102.5 CBZ40964.1 - 6.1e-12 45.3 4.2 6.1e-12 45.3 4.2 1.9 2 0 0 2 2 2 1 Stealth protein CR3, conserved region 3 DUF5631 PF18645.1 CBZ40964.1 - 0.06 13.7 0.1 0.28 11.6 0.1 2.1 1 0 0 1 1 1 0 Family of unknown function (DUF5631) Peptidase_C1 PF00112.23 CBZ40965.1 - 1.6e-33 116.6 0.5 2.2e-33 116.2 0.5 1.2 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.12 CBZ40965.1 - 4.3e-12 46.3 0.9 6.6e-12 45.7 0.9 1.3 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1 PF00112.23 CBZ40966.1 - 1.1e-70 238.1 0.8 1.1e-70 238.1 0.8 1.9 2 0 0 2 2 2 1 Papain family cysteine protease DUF3586 PF12131.8 CBZ40966.1 - 7.5e-20 70.9 8.9 7.5e-20 70.9 8.9 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF3586) Inhibitor_I29 PF08246.12 CBZ40966.1 - 1.4e-11 44.7 0.9 2.2e-11 44.0 0.9 1.4 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.15 CBZ40966.1 - 8.9e-06 24.7 0.2 0.00091 18.1 0.1 2.1 2 0 0 2 2 2 2 Peptidase C1-like family MBOAT PF03062.19 CBZ40967.1 - 4.6e-29 101.9 13.7 8.6e-29 101.0 13.7 1.4 1 0 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family PUF PF00806.19 CBZ40968.1 - 3.8e-18 64.1 0.0 0.0024 17.5 0.0 4.5 4 0 0 4 4 4 4 Pumilio-family RNA binding repeat PUF PF00806.19 CBZ40969.1 - 1.4e-07 30.8 0.0 0.0028 17.3 0.0 2.6 2 0 0 2 2 2 2 Pumilio-family RNA binding repeat TCTP PF00838.17 CBZ40970.1 - 9.1e-44 149.7 0.6 1e-43 149.6 0.6 1.0 1 0 0 1 1 1 1 Translationally controlled tumour protein RICH PF05062.12 CBZ40970.1 - 0.044 14.1 0.4 0.075 13.4 0.4 1.3 1 0 0 1 1 1 0 RICH domain DUF273 PF03314.14 CBZ40970.1 - 0.053 13.1 0.7 0.67 9.5 0.6 2.0 1 1 1 2 2 2 0 Protein of unknown function, DUF273 Cauli_DNA-bind PF03310.13 CBZ40970.1 - 0.13 12.3 0.1 0.39 10.8 0.0 1.7 2 0 0 2 2 2 0 Caulimovirus DNA-binding protein UPF0262 PF06793.12 CBZ40970.1 - 0.14 12.3 0.2 0.18 11.9 0.2 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0262) Peripla_BP_6 PF13458.6 CBZ40971.1 - 1.5e-09 38.0 0.1 3.7e-07 30.1 0.0 2.3 2 0 0 2 2 2 2 Periplasmic binding protein RL10P_insert PF17777.1 CBZ40973.1 - 1.9e-20 72.6 0.2 3.3e-20 71.8 0.2 1.4 1 0 0 1 1 1 1 Insertion domain in 60S ribosomal protein L10P Ribosomal_L10 PF00466.20 CBZ40973.1 - 3.3e-17 62.5 0.1 6.9e-17 61.4 0.1 1.5 1 0 0 1 1 1 1 Ribosomal protein L10 Ribosomal_60s PF00428.19 CBZ40973.1 - 2.9e-14 53.4 3.8 2.9e-14 53.4 3.8 2.3 3 0 0 3 3 3 1 60s Acidic ribosomal protein RL10P_insert PF17777.1 CBZ40974.1 - 1.3e-17 63.5 0.2 2.2e-17 62.8 0.2 1.4 1 0 0 1 1 1 1 Insertion domain in 60S ribosomal protein L10P Ribosomal_60s PF00428.19 CBZ40974.1 - 1e-14 54.8 5.5 1.1e-14 54.8 3.8 1.9 2 0 0 2 2 2 1 60s Acidic ribosomal protein Pkinase PF00069.25 CBZ40975.1 - 2e-41 142.1 0.0 2.5e-41 141.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ40975.1 - 6.4e-17 61.7 0.0 8.7e-17 61.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 CBZ40975.1 - 0.018 14.9 0.4 1.9 8.3 0.0 2.4 2 0 0 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.14 CBZ40975.1 - 0.026 13.9 0.1 0.047 13.0 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 CBZ40975.1 - 0.2 10.6 0.0 0.23 10.4 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain ApoB100_C PF12491.8 CBZ40976.1 - 1.2e-19 70.0 88.0 5 7.2 0.2 19.9 3 1 20 23 23 22 7 Apolipoprotein B100 C terminal Laminin_I PF06008.14 CBZ40976.1 - 3.4e-19 69.6 170.7 0.0083 15.9 16.0 9.8 1 1 5 7 7 7 7 Laminin Domain I Spc7 PF08317.11 CBZ40976.1 - 3.8e-18 65.4 178.4 0.0016 17.4 27.8 6.8 1 1 7 8 8 8 8 Spc7 kinetochore protein DUF3552 PF12072.8 CBZ40976.1 - 2.1e-11 43.6 161.2 0.37 10.2 13.9 10.7 1 1 13 14 14 14 13 Domain of unknown function (DUF3552) KxDL PF10241.9 CBZ40976.1 - 5.2e-11 42.7 126.5 0.63 10.4 7.6 12.0 1 1 12 13 13 13 8 Uncharacterized conserved protein COG2 PF06148.11 CBZ40976.1 - 8.9e-11 42.0 105.2 0.64 10.1 5.2 11.7 1 1 15 16 16 16 14 COG (conserved oligomeric Golgi) complex component, COG2 Laminin_II PF06009.12 CBZ40976.1 - 5.2e-09 36.2 137.5 0.46 10.5 11.7 10.3 1 1 9 10 10 10 9 Laminin Domain II IFT57 PF10498.9 CBZ40976.1 - 7.4e-08 31.7 139.8 0.42 9.5 21.6 7.4 1 1 4 6 6 6 4 Intra-flagellar transport protein 57 Herpes_BLLF1 PF05109.13 CBZ40976.1 - 8.2e-08 30.7 41.5 0.079 10.9 4.8 4.9 1 1 3 5 5 5 5 Herpes virus major outer envelope glycoprotein (BLLF1) V-SNARE_C PF12352.8 CBZ40976.1 - 9.2e-08 32.3 78.0 2.5 8.4 3.3 12.1 2 1 11 14 14 14 8 Snare region anchored in the vesicle membrane C-terminus ATG16 PF08614.11 CBZ40976.1 - 1.4e-06 28.7 211.6 0.48 10.6 4.2 7.5 1 1 5 6 6 4 2 Autophagy protein 16 (ATG16) TMF_DNA_bd PF12329.8 CBZ40976.1 - 8.1e-06 25.7 194.7 0.016 15.2 14.1 14.4 2 1 24 27 27 27 2 TATA element modulatory factor 1 DNA binding Filament PF00038.21 CBZ40976.1 - 6.2e-05 22.7 154.5 0.0018 17.9 7.4 8.8 1 1 3 4 4 3 1 Intermediate filament protein Tropomyosin_1 PF12718.7 CBZ40976.1 - 9.9e-05 22.5 212.3 2.9 8.1 37.8 8.5 1 1 8 9 9 9 1 Tropomyosin like MscS_porin PF12795.7 CBZ40976.1 - 0.00029 20.4 220.5 3.4 7.1 21.7 9.1 1 1 8 9 9 8 1 Mechanosensitive ion channel porin domain Exonuc_VII_L PF02601.15 CBZ40976.1 - 0.00034 20.3 128.8 9.9 5.6 22.1 6.2 1 1 2 3 3 2 0 Exonuclease VII, large subunit Tropomyosin PF00261.20 CBZ40976.1 - 0.00037 20.0 192.9 0.093 12.1 39.7 6.2 1 1 4 6 6 6 3 Tropomyosin TMF_TATA_bd PF12325.8 CBZ40976.1 - 0.0025 18.0 173.0 2.5 8.4 12.0 11.0 1 1 9 10 10 10 1 TATA element modulatory factor 1 TATA binding ApoO PF09769.9 CBZ40976.1 - 0.003 17.5 84.9 14 5.7 1.0 12.9 1 1 22 23 23 23 0 Apolipoprotein O EzrA PF06160.12 CBZ40976.1 - 0.0051 15.0 130.3 0.022 13.0 61.0 2.5 1 1 1 2 2 2 2 Septation ring formation regulator, EzrA HrpB7 PF09486.10 CBZ40976.1 - 0.0054 17.1 152.3 1.5 9.2 7.5 8.5 1 1 8 9 9 9 1 Bacterial type III secretion protein (HrpB7) DHR10 PF18595.1 CBZ40976.1 - 0.0061 16.6 198.5 0.56 10.3 27.2 10.6 1 1 9 10 10 8 1 Designed helical repeat protein 10 domain DUF4200 PF13863.6 CBZ40976.1 - 0.028 14.8 155.0 10 6.5 20.8 10.0 1 1 8 9 9 7 0 Domain of unknown function (DUF4200) Atg14 PF10186.9 CBZ40976.1 - 0.035 13.2 133.2 2.6 7.0 18.2 6.4 1 1 6 7 7 7 0 Vacuolar sorting 38 and autophagy-related subunit 14 Myosin_tail_1 PF01576.19 CBZ40976.1 - 0.056 11.2 163.9 0.13 10.1 37.5 4.9 1 1 4 5 5 5 0 Myosin tail DUF1664 PF07889.12 CBZ40976.1 - 0.21 11.7 104.5 3.9 7.5 6.1 9.4 1 1 3 5 5 4 0 Protein of unknown function (DUF1664) UPF0449 PF15136.6 CBZ40976.1 - 0.48 10.9 136.5 24 5.5 6.9 14.0 1 1 11 12 12 9 0 Uncharacterised protein family UPF0449 DUF5082 PF16888.5 CBZ40976.1 - 0.78 10.0 0.0 0.78 10.0 0.0 12.3 2 1 2 4 4 1 0 Domain of unknown function (DUF5082) MAD PF05557.13 CBZ40976.1 - 3.1 6.0 159.0 5.1 5.3 35.8 5.0 1 1 4 5 5 5 0 Mitotic checkpoint protein Snapin_Pallidin PF14712.6 CBZ40976.1 - 8.9 6.8 119.3 1.6 9.2 11.3 9.9 1 1 12 13 13 13 0 Snapin/Pallidin MCPsignal PF00015.21 CBZ40976.1 - 9.2 6.0 110.1 17 5.2 11.6 8.6 1 1 8 9 9 7 0 Methyl-accepting chemotaxis protein (MCP) signalling domain Amastin PF07344.11 CBZ40977.1 - 5e-47 159.6 10.6 6e-47 159.4 10.6 1.1 1 0 0 1 1 1 1 Amastin surface glycoprotein DUF805 PF05656.14 CBZ40977.1 - 0.19 12.1 9.9 0.027 14.9 5.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF805) TolA_bind_tri PF16331.5 CBZ40978.1 - 2.2e-34 117.4 152.9 0.23 11.6 0.6 22.1 1 1 18 22 22 22 17 TolA binding protein trimerisation UPF0242 PF06785.11 CBZ40978.1 - 1.2e-22 81.0 187.6 0.0098 16.0 13.7 10.9 1 1 10 11 11 11 10 Uncharacterised protein family (UPF0242) N-terminus THOC7 PF05615.13 CBZ40978.1 - 1.6e-21 77.0 197.8 0.13 12.6 4.2 21.0 1 1 20 21 21 21 21 Tho complex subunit 7 HMMR_N PF15905.5 CBZ40978.1 - 3.1e-18 66.4 154.4 0.065 12.7 10.6 12.7 1 1 12 13 13 13 11 Hyaluronan mediated motility receptor N-terminal MscS_porin PF12795.7 CBZ40978.1 - 7.2e-18 65.0 188.8 0.0002 21.0 38.1 7.8 1 1 6 8 8 8 8 Mechanosensitive ion channel porin domain DHR10 PF18595.1 CBZ40978.1 - 2.7e-12 46.8 233.6 0.13 12.4 15.5 11.1 1 1 12 13 13 13 12 Designed helical repeat protein 10 domain HOOK PF05622.12 CBZ40978.1 - 2.3e-11 42.6 171.4 0.0022 16.3 21.3 7.2 1 1 6 8 8 8 8 HOOK protein Golgin_A5 PF09787.9 CBZ40978.1 - 9.2e-11 41.7 172.2 0.094 12.2 23.2 7.2 1 1 6 7 7 7 7 Golgin subfamily A member 5 TPR_MLP1_2 PF07926.12 CBZ40978.1 - 4.7e-10 39.6 208.3 0.39 10.8 31.5 10.6 1 1 11 12 12 12 9 TPR/MLP1/MLP2-like protein Lebercilin PF15619.6 CBZ40978.1 - 1.2e-09 38.1 178.3 0.024 14.3 17.5 8.3 1 1 12 13 13 13 12 Ciliary protein causing Leber congenital amaurosis disease CENP-F_leu_zip PF10473.9 CBZ40978.1 - 2.1e-09 37.5 196.3 0.21 11.6 15.6 10.7 1 1 12 13 13 13 7 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 COG5 PF10392.9 CBZ40978.1 - 2.1e-09 37.6 48.0 2.5 8.3 0.3 13.7 1 1 18 19 19 19 7 Golgi transport complex subunit 5 DUF4201 PF13870.6 CBZ40978.1 - 2.9e-08 33.6 126.0 0.32 10.7 13.3 9.9 1 1 12 13 13 13 12 Domain of unknown function (DUF4201) DUF536 PF04394.14 CBZ40978.1 - 1.5e-07 31.2 169.3 6.4 6.7 0.9 26.1 22 9 0 22 22 22 0 Protein of unknown function, DUF536 DUF2353 PF09789.9 CBZ40978.1 - 2.9e-06 26.9 144.1 0.18 11.1 27.2 6.5 1 1 6 8 8 8 7 Uncharacterized coiled-coil protein (DUF2353) Fez1 PF06818.15 CBZ40978.1 - 3.3e-06 27.7 164.7 3.3 8.1 23.1 7.7 1 1 5 6 6 5 1 Fez1 TMF_TATA_bd PF12325.8 CBZ40978.1 - 3.8e-06 27.1 165.9 2.5 8.3 15.1 14.5 1 1 15 16 16 16 3 TATA element modulatory factor 1 TATA binding PI3K_P85_iSH2 PF16454.5 CBZ40978.1 - 1.5e-05 24.7 123.1 0.61 9.7 5.7 10.6 1 1 10 12 12 12 5 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain APG6_N PF17675.1 CBZ40978.1 - 3.4e-05 24.4 251.7 2.8 8.5 29.5 11.3 1 1 11 13 13 13 1 Apg6 coiled-coil region Filament PF00038.21 CBZ40978.1 - 4e-05 23.4 153.1 1.7 8.1 6.1 12.4 1 1 11 12 12 10 5 Intermediate filament protein Spc7 PF08317.11 CBZ40978.1 - 5.1e-05 22.3 186.2 0.21 10.4 18.2 8.8 1 1 11 12 12 12 4 Spc7 kinetochore protein GAS PF13851.6 CBZ40978.1 - 6.5e-05 22.4 165.6 0.65 9.3 16.4 11.8 1 1 13 15 15 15 5 Growth-arrest specific micro-tubule binding MAD PF05557.13 CBZ40978.1 - 0.00015 20.3 165.2 0.61 8.4 19.0 7.5 1 1 8 9 9 9 7 Mitotic checkpoint protein HAP1_N PF04849.13 CBZ40978.1 - 0.00018 20.8 159.0 0.46 9.6 15.4 9.1 1 1 7 8 8 8 3 HAP1 N-terminal conserved region DUF4407 PF14362.6 CBZ40978.1 - 0.0015 18.0 184.3 10 5.4 25.5 7.4 1 1 3 4 4 2 0 Domain of unknown function (DUF4407) Rab5-bind PF09311.11 CBZ40978.1 - 0.097 12.0 142.4 0.9 8.9 14.8 9.6 1 1 16 17 17 17 0 Rabaptin-like protein Jnk-SapK_ap_N PF09744.9 CBZ40978.1 - 0.28 11.4 195.7 9.2 6.5 10.6 11.9 1 1 16 17 17 17 0 JNK_SAPK-associated protein-1 Taxilin PF09728.9 CBZ40978.1 - 0.29 10.3 136.8 12 5.0 37.2 8.9 1 1 3 5 5 5 0 Myosin-like coiled-coil protein PRKG1_interact PF15898.5 CBZ40978.1 - 0.37 11.7 168.6 9.6 7.2 11.0 14.7 1 1 15 16 16 16 0 cGMP-dependent protein kinase interacting domain CCDC144C PF14915.6 CBZ40978.1 - 0.37 9.9 155.7 3.8 6.6 6.8 10.3 1 1 8 11 11 11 0 CCDC144C protein coiled-coil region Rootletin PF15035.6 CBZ40978.1 - 0.59 10.1 184.7 9.5 6.2 11.9 13.9 1 1 14 15 15 15 0 Ciliary rootlet component, centrosome cohesion Laminin_I PF06008.14 CBZ40978.1 - 1.6 8.3 136.5 2.9 7.5 6.2 7.8 1 1 8 9 9 9 0 Laminin Domain I CALCOCO1 PF07888.11 CBZ40978.1 - 5.8 5.7 180.1 14 4.4 51.1 6.0 1 1 5 6 6 6 0 Calcium binding and coiled-coil domain (CALCOCO1) like Atg14 PF10186.9 CBZ40978.1 - 5.8 5.9 142.5 1.4 8.0 15.9 7.9 1 1 6 7 7 5 0 Vacuolar sorting 38 and autophagy-related subunit 14 Kinesin PF00225.23 CBZ40981.1 - 1e-78 264.6 1.2 1.3e-77 261.0 0.0 3.7 2 1 0 2 2 2 1 Kinesin motor domain Laminin_I PF06008.14 CBZ40981.1 - 8.6e-35 120.7 382.0 0.021 14.5 18.1 20.2 1 1 22 23 23 21 21 Laminin Domain I Spc7 PF08317.11 CBZ40981.1 - 1.7e-34 119.1 396.4 0.00044 19.2 25.5 14.1 1 1 13 14 14 14 12 Spc7 kinetochore protein ApoB100_C PF12491.8 CBZ40981.1 - 5.1e-29 100.0 201.9 10 6.2 0.3 43.1 3 1 54 58 58 57 0 Apolipoprotein B100 C terminal Microtub_bd PF16796.5 CBZ40981.1 - 2.8e-21 76.0 0.0 1.9e-20 73.3 0.0 2.6 1 0 0 1 1 1 1 Microtubule binding COG2 PF06148.11 CBZ40981.1 - 1.9e-16 60.4 229.7 1.4 9.0 8.3 24.3 1 1 29 30 30 30 25 COG (conserved oligomeric Golgi) complex component, COG2 DUF3552 PF12072.8 CBZ40981.1 - 3.7e-15 55.9 356.8 0.85 9.0 11.1 23.0 1 1 24 26 26 24 14 Domain of unknown function (DUF3552) KxDL PF10241.9 CBZ40981.1 - 3.8e-14 52.7 287.1 0.046 14.0 6.4 24.2 3 1 27 31 31 30 22 Uncharacterized conserved protein IFT57 PF10498.9 CBZ40981.1 - 1.9e-12 46.8 316.6 0.08 11.9 17.6 15.4 1 1 9 12 12 12 9 Intra-flagellar transport protein 57 Laminin_II PF06009.12 CBZ40981.1 - 2.5e-12 47.0 310.2 0.41 10.7 11.7 21.6 2 1 22 24 24 23 13 Laminin Domain II Herpes_BLLF1 PF05109.13 CBZ40981.1 - 2.4e-11 42.4 105.4 0.44 8.5 4.7 11.4 1 1 11 12 12 12 11 Herpes virus major outer envelope glycoprotein (BLLF1) V-SNARE_C PF12352.8 CBZ40981.1 - 1.7e-10 41.0 177.5 3.1 8.1 1.5 24.6 2 1 19 25 25 24 9 Snare region anchored in the vesicle membrane C-terminus ATG16 PF08614.11 CBZ40981.1 - 0.0015 18.8 467.1 0.59 10.3 36.1 14.5 1 1 12 13 13 7 1 Autophagy protein 16 (ATG16) Tropomyosin PF00261.20 CBZ40981.1 - 0.0048 16.3 429.7 0.17 11.3 36.5 12.3 1 1 10 11 11 8 8 Tropomyosin Exonuc_VII_L PF02601.15 CBZ40981.1 - 0.0051 16.4 283.2 9.7 5.7 19.8 13.2 1 1 2 3 3 1 0 Exonuclease VII, large subunit EzrA PF06160.12 CBZ40981.1 - 0.11 10.7 300.3 0.098 10.8 66.7 6.3 1 1 5 6 6 6 0 Septation ring formation regulator, EzrA Atg14 PF10186.9 CBZ40981.1 - 0.11 11.6 285.6 4.3 6.3 29.4 12.6 1 1 12 13 13 13 0 Vacuolar sorting 38 and autophagy-related subunit 14 L31 PF09784.9 CBZ40981.1 - 0.33 11.4 2.1 35 4.9 2.1 4.8 1 0 0 1 1 1 0 Mitochondrial ribosomal protein L31 Tropomyosin_1 PF12718.7 CBZ40981.1 - 0.74 10.0 474.7 6.6 6.9 29.5 17.5 1 1 18 19 19 17 0 Tropomyosin like ApoO PF09769.9 CBZ40981.1 - 1.2 9.2 187.4 11 6.0 0.5 27.8 1 1 37 38 38 38 0 Apolipoprotein O Filament PF00038.21 CBZ40981.1 - 6.2 6.3 346.0 0.17 11.4 25.8 17.7 1 1 9 10 10 6 0 Intermediate filament protein Amastin PF07344.11 CBZ40982.1 - 1.1e-49 168.2 8.4 1.4e-49 167.9 8.4 1.0 1 0 0 1 1 1 1 Amastin surface glycoprotein DUF4525 PF15027.6 CBZ40982.1 - 0.72 9.6 0.0 0.72 9.6 0.0 2.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4525) DUF4407 PF14362.6 CBZ40982.1 - 0.96 8.7 3.4 1.6 8.0 3.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) UNC-50 PF05216.13 CBZ40982.1 - 3.5 7.1 11.1 0.12 11.9 4.6 1.7 2 0 0 2 2 2 0 UNC-50 family Peptidase_C2 PF00648.21 CBZ40983.1 - 2.2e-14 53.2 1.3 3.1e-14 52.7 1.3 1.2 1 0 0 1 1 1 1 Calpain family cysteine protease Calpain_III PF01067.22 CBZ40983.1 - 0.0034 17.7 0.0 0.0048 17.2 0.0 1.3 1 0 0 1 1 1 1 Calpain large subunit, domain III Amastin PF07344.11 CBZ40984.1 - 2.9e-56 189.6 7.7 3.5e-56 189.4 7.7 1.1 1 0 0 1 1 1 1 Amastin surface glycoprotein DUF1218 PF06749.12 CBZ40984.1 - 0.00057 20.3 15.4 2.5 8.7 0.1 3.8 1 1 2 3 3 3 3 Protein of unknown function (DUF1218) DUF4293 PF14126.6 CBZ40984.1 - 7.4 6.8 10.6 44 4.3 10.6 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF4293) Peptidase_M8 PF01457.16 CBZ40986.1 - 3.6e-125 418.7 0.2 4.2e-125 418.4 0.2 1.0 1 0 0 1 1 1 1 Leishmanolysin Zincin_1 PF06262.11 CBZ40986.1 - 0.0068 16.5 0.0 0.018 15.1 0.0 1.7 1 0 0 1 1 1 1 Zincin-like metallopeptidase Peptidase_M57 PF12388.8 CBZ40986.1 - 0.02 14.5 0.0 0.035 13.7 0.0 1.4 1 0 0 1 1 1 0 Dual-action HEIGH metallo-peptidase Peptidase_M7 PF02031.16 CBZ40986.1 - 0.07 13.3 0.1 0.18 11.9 0.0 1.7 1 1 1 2 2 2 0 Streptomyces extracellular neutral proteinase (M7) family Inhibitor_I29 PF08246.12 CBZ40987.1 - 2.3e-10 40.8 0.2 2.6e-10 40.6 0.2 1.1 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1 PF00112.23 CBZ40988.1 - 6.4e-71 238.9 0.7 6.4e-71 238.9 0.7 1.9 2 0 0 2 2 2 1 Papain family cysteine protease DUF3586 PF12131.8 CBZ40988.1 - 8.2e-20 70.8 8.9 8.2e-20 70.8 8.9 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF3586) Inhibitor_I29 PF08246.12 CBZ40988.1 - 1.5e-11 44.5 0.9 2.4e-11 43.9 0.9 1.3 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.15 CBZ40988.1 - 1e-05 24.5 0.2 0.00099 18.0 0.1 2.1 2 0 0 2 2 2 2 Peptidase C1-like family Brix PF04427.18 CBZ40989.1 - 6.7e-29 101.4 0.0 8.7e-29 101.0 0.0 1.1 1 0 0 1 1 1 1 Brix domain Mito_carr PF00153.27 CBZ40990.1 - 6.9e-54 179.8 0.5 3.6e-19 68.5 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein Amastin PF07344.11 CBZ40992.1 - 8.4e-49 165.4 11.4 1e-48 165.1 11.4 1.0 1 0 0 1 1 1 1 Amastin surface glycoprotein DUF2427 PF10348.9 CBZ40992.1 - 0.0049 16.6 5.4 0.093 12.5 1.1 2.6 2 1 0 2 2 2 2 Domain of unknown function (DUF2427) YwcE PF17368.2 CBZ40992.1 - 0.17 12.6 5.2 0.41 11.3 0.1 2.6 1 1 0 2 2 2 0 Spore morphogenesis and germination YwcE DUF4293 PF14126.6 CBZ40992.1 - 0.2 11.9 3.8 0.7 10.1 3.8 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4293) RSN1_TM PF13967.6 CBZ40992.1 - 6 6.6 9.1 0.5 10.1 3.8 1.9 2 0 0 2 2 2 0 Late exocytosis, associated with Golgi transport Amastin PF07344.11 CBZ40994.1 - 7.2e-56 188.3 11.1 8.5e-56 188.1 11.1 1.0 1 0 0 1 1 1 1 Amastin surface glycoprotein PMP22_Claudin PF00822.20 CBZ40994.1 - 0.0021 17.9 4.8 0.0021 17.9 4.8 1.8 2 0 0 2 2 2 1 PMP-22/EMP/MP20/Claudin family DUF1218 PF06749.12 CBZ40994.1 - 0.0031 18.0 15.0 2.7 8.6 0.2 3.9 1 1 2 3 3 3 2 Protein of unknown function (DUF1218) SUR7 PF06687.12 CBZ40994.1 - 2 8.0 17.8 16 5.1 8.2 3.0 3 0 0 3 3 3 0 SUR7/PalI family DUF4293 PF14126.6 CBZ40994.1 - 3.1 8.0 10.2 11 6.3 10.2 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4293) DUF1467 PF07330.12 CBZ40994.1 - 4.5 7.3 0.0 4.5 7.3 0.0 3.5 3 1 1 4 4 4 0 Protein of unknown function (DUF1467) Amastin PF07344.11 CBZ40995.1 - 4.8e-47 159.7 10.6 5.7e-47 159.4 10.6 1.0 1 0 0 1 1 1 1 Amastin surface glycoprotein DUF805 PF05656.14 CBZ40995.1 - 0.19 12.2 9.9 0.026 14.9 5.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF805) Claudin_2 PF13903.6 CBZ40995.1 - 8.9 6.0 15.6 0.8 9.4 10.9 1.7 2 1 0 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction Amastin PF07344.11 CBZ40996.1 - 5.6e-54 182.2 9.6 6.6e-54 182.0 9.6 1.1 1 0 0 1 1 1 1 Amastin surface glycoprotein DUF3087 PF11286.8 CBZ40996.1 - 0.15 11.5 0.1 0.29 10.6 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3087) Vpu PF00558.19 CBZ40996.1 - 0.26 11.1 0.2 0.26 11.1 0.2 2.8 3 0 0 3 3 3 0 Vpu protein SUR7 PF06687.12 CBZ40996.1 - 3.7 7.1 18.0 5.1 6.6 12.4 2.3 2 1 0 2 2 2 0 SUR7/PalI family Peptidase_C2 PF00648.21 CBZ40997.1 - 3.1e-63 213.5 0.0 4.1e-63 213.2 0.0 1.1 1 0 0 1 1 1 1 Calpain family cysteine protease DUF1935 PF09149.10 CBZ40997.1 - 2.6e-17 63.1 0.2 5.4e-17 62.1 0.2 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1935) Calpain_III PF01067.22 CBZ40997.1 - 0.022 15.0 0.0 0.056 13.7 0.0 1.7 1 0 0 1 1 1 0 Calpain large subunit, domain III Amastin PF07344.11 CBZ40998.1 - 9.4e-50 168.5 9.0 1.1e-49 168.2 9.0 1.1 1 0 0 1 1 1 1 Amastin surface glycoprotein DUF4407 PF14362.6 CBZ40998.1 - 9.1 5.5 5.7 18 4.6 5.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Peptidase_C2 PF00648.21 CBZ40999.1 - 1.4e-63 214.7 0.0 1.9e-63 214.3 0.0 1.1 1 0 0 1 1 1 1 Calpain family cysteine protease DUF1935 PF09149.10 CBZ40999.1 - 2.6e-17 63.1 0.2 5.4e-17 62.1 0.2 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1935) Calpain_III PF01067.22 CBZ40999.1 - 0.012 15.9 0.0 0.031 14.6 0.0 1.7 1 0 0 1 1 1 0 Calpain large subunit, domain III Amastin PF07344.11 CBZ41000.1 - 4.7e-51 172.7 8.5 5.6e-51 172.4 8.5 1.1 1 0 0 1 1 1 1 Amastin surface glycoprotein DUF4407 PF14362.6 CBZ41000.1 - 1.4 8.2 5.0 2 7.7 5.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF3087 PF11286.8 CBZ41000.1 - 2.8 7.4 4.7 0.42 10.1 0.6 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3087) Amastin PF07344.11 CBZ41001.1 - 1.5e-50 171.1 10.1 1.8e-50 170.8 10.1 1.0 1 0 0 1 1 1 1 Amastin surface glycoprotein DUF983 PF06170.12 CBZ41001.1 - 0.016 15.6 1.5 0.016 15.6 1.5 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF983) DUF4293 PF14126.6 CBZ41001.1 - 0.3 11.3 6.1 1.7 8.9 6.1 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4293) LYRIC PF15686.5 CBZ41001.1 - 0.31 10.5 0.1 0.42 10.1 0.1 1.1 1 0 0 1 1 1 0 Lysine-rich CEACAM1 co-isolated protein family DUF3671 PF12420.8 CBZ41001.1 - 1.4 9.0 5.5 0.55 10.3 1.1 2.1 2 0 0 2 2 2 0 Protein of unknown function SPP PF06550.11 CBZ41001.1 - 2.7 7.4 10.3 0.037 13.5 0.6 2.3 2 1 0 2 2 2 0 Signal-peptide peptidase, presenilin aspartyl protease PRA1 PF03208.19 CBZ41001.1 - 7.3 6.2 11.1 1.9 8.1 2.8 2.4 1 1 1 2 2 2 0 PRA1 family protein Amastin PF07344.11 CBZ41002.1 - 6.5e-34 117.0 7.9 8e-34 116.7 7.9 1.0 1 0 0 1 1 1 1 Amastin surface glycoprotein DUF983 PF06170.12 CBZ41002.1 - 0.0098 16.3 1.8 0.0098 16.3 1.8 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF983) Phage_holin_3_6 PF07332.11 CBZ41002.1 - 0.022 14.8 2.5 0.022 14.8 2.5 1.9 2 0 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III DUF4293 PF14126.6 CBZ41002.1 - 0.038 14.2 0.5 0.061 13.6 0.5 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4293) DUF2721 PF11026.8 CBZ41002.1 - 0.13 12.2 5.5 0.073 13.0 2.6 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2721) DUF3671 PF12420.8 CBZ41002.1 - 0.16 12.0 1.1 0.27 11.3 1.1 1.3 1 0 0 1 1 1 0 Protein of unknown function LYRIC PF15686.5 CBZ41002.1 - 0.18 11.3 0.1 0.24 10.9 0.1 1.1 1 0 0 1 1 1 0 Lysine-rich CEACAM1 co-isolated protein family Peptidase_C2 PF00648.21 CBZ41003.1 - 1.5e-64 217.9 0.0 1.9e-64 217.6 0.0 1.1 1 0 0 1 1 1 1 Calpain family cysteine protease Calpain_III PF01067.22 CBZ41003.1 - 0.02 15.1 0.0 0.051 13.8 0.0 1.7 1 0 0 1 1 1 0 Calpain large subunit, domain III Sulfotransfer_4 PF17784.1 CBZ41004.1 - 6.6e-42 143.8 0.0 1.7e-41 142.4 0.0 1.6 1 1 0 1 1 1 1 Sulfotransferase domain cNMP_binding PF00027.29 CBZ41005.1 - 9.2e-09 35.3 0.6 0.0018 18.3 0.2 3.2 2 1 0 2 2 2 2 Cyclic nucleotide-binding domain Kinesin PF00225.23 CBZ41006.1 - 1.9e-23 83.0 0.0 1.9e-23 83.0 0.0 3.0 2 1 1 3 3 3 1 Kinesin motor domain Myosin_tail_1 PF01576.19 CBZ41006.1 - 1e-10 40.2 126.5 1.1e-07 30.2 62.8 5.1 1 1 3 4 4 3 2 Myosin tail Spc7 PF08317.11 CBZ41006.1 - 2.9e-10 39.5 172.9 0.0025 16.8 16.5 8.9 1 1 10 11 11 9 8 Spc7 kinetochore protein ATG16 PF08614.11 CBZ41006.1 - 1e-05 25.9 190.2 0.0062 16.8 34.3 8.6 1 1 8 9 9 7 6 Autophagy protein 16 (ATG16) M PF02370.16 CBZ41006.1 - 5.2e-05 23.3 233.4 0.74 10.6 2.1 31.0 10 5 25 37 37 37 22 M protein repeat HMMR_N PF15905.5 CBZ41006.1 - 0.0004 20.0 80.2 0.0013 18.3 42.4 5.0 1 1 2 4 4 3 3 Hyaluronan mediated motility receptor N-terminal Jnk-SapK_ap_N PF09744.9 CBZ41006.1 - 0.0071 16.6 13.6 0.0071 16.6 13.6 10.1 1 1 8 9 9 6 6 JNK_SAPK-associated protein-1 WXG100 PF06013.12 CBZ41006.1 - 0.065 13.5 85.6 10 6.5 2.5 16.2 5 3 11 17 17 17 0 Proteins of 100 residues with WXG APG6_N PF17675.1 CBZ41006.1 - 0.52 10.8 211.2 1.1 9.8 13.9 11.6 1 1 6 7 7 3 0 Apg6 coiled-coil region Taxilin PF09728.9 CBZ41006.1 - 0.64 9.1 179.9 0.024 13.8 13.2 8.9 1 1 8 10 10 9 0 Myosin-like coiled-coil protein MscS_porin PF12795.7 CBZ41006.1 - 0.72 9.4 144.3 0.23 11.0 4.2 11.0 1 1 8 9 9 6 0 Mechanosensitive ion channel porin domain WD40 PF00400.32 CBZ41007.1 - 1.4e-45 152.3 19.5 3.2e-08 34.1 0.0 7.1 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBZ41007.1 - 7.7e-13 48.6 0.3 0.011 16.1 0.0 4.1 1 1 4 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 CBZ41007.1 - 2.6e-09 36.3 3.1 0.016 13.9 0.2 3.9 1 1 3 4 4 4 3 Nucleoporin Nup120/160 eIF2A PF08662.11 CBZ41007.1 - 2.4e-07 30.8 0.0 0.00031 20.7 0.0 2.7 1 1 2 3 3 3 3 Eukaryotic translation initiation factor eIF2A PD40 PF07676.12 CBZ41007.1 - 6.7e-05 22.7 0.0 1.8 8.6 0.0 4.7 5 0 0 5 5 5 1 WD40-like Beta Propeller Repeat Ge1_WD40 PF16529.5 CBZ41007.1 - 0.00028 20.0 1.5 0.029 13.3 0.8 3.5 1 1 2 4 4 4 1 WD40 region of Ge1, enhancer of mRNA-decapping protein PQQ_2 PF13360.6 CBZ41007.1 - 0.0013 18.3 0.0 0.12 11.9 0.0 1.9 1 1 1 2 2 2 2 PQQ-like domain WD40_like PF17005.5 CBZ41007.1 - 0.0068 15.8 0.0 0.0091 15.3 0.0 1.3 1 0 0 1 1 1 1 WD40-like domain Cytochrom_D1 PF02239.16 CBZ41007.1 - 0.048 12.2 0.0 1.2 7.6 0.0 2.3 2 0 0 2 2 2 0 Cytochrome D1 heme domain Coatomer_WDAD PF04053.14 CBZ41007.1 - 0.21 10.6 0.0 0.56 9.2 0.0 1.5 1 1 1 2 2 2 0 Coatomer WD associated region WD40 PF00400.32 CBZ41008.1 - 7.2e-16 58.3 2.5 2.9e-06 27.9 0.3 3.2 3 0 0 3 3 3 3 WD domain, G-beta repeat Nup160 PF11715.8 CBZ41008.1 - 0.0018 17.0 0.2 0.0021 16.8 0.1 1.2 1 1 0 1 1 1 1 Nucleoporin Nup120/160 Lectin_leg-like PF03388.13 CBZ41010.1 - 8.3e-11 41.7 0.0 1.1e-05 24.8 0.0 3.2 2 1 0 2 2 2 2 Legume-like lectin family YL1 PF05764.13 CBZ41010.1 - 0.00073 19.7 0.6 0.0011 19.2 0.6 1.3 1 0 0 1 1 1 1 YL1 nuclear protein HTH_IclR PF09339.10 CBZ41012.1 - 0.0031 17.3 0.0 4.4 7.2 0.0 2.6 2 0 0 2 2 2 2 IclR helix-turn-helix domain Amastin PF07344.11 CBZ41013.1 - 3.5e-53 179.6 6.8 5.3e-53 179.0 6.8 1.3 1 0 0 1 1 1 1 Amastin surface glycoprotein Amastin PF07344.11 CBZ41015.1 - 2.1e-51 173.8 10.6 2.6e-51 173.5 10.6 1.1 1 0 0 1 1 1 1 Amastin surface glycoprotein Adeno_E3_14_5 PF04834.12 CBZ41015.1 - 0.13 12.8 0.8 0.35 11.4 0.8 1.8 1 0 0 1 1 1 0 Early E3 14.5 kDa protein PBP_like PF12727.7 CBZ41016.1 - 0.048 12.8 0.9 9.9 5.2 0.1 2.6 2 0 0 2 2 2 0 PBP superfamily domain DUF3500 PF12006.8 CBZ41016.1 - 0.17 11.3 2.8 18 4.7 0.2 3.3 2 2 0 2 2 2 0 Protein of unknown function (DUF3500) SopA_C PF13979.6 CBZ41016.1 - 2.2 8.0 5.1 39 3.9 0.3 3.2 3 0 0 3 3 3 0 SopA-like catalytic domain Zip PF02535.22 CBZ41018.1 - 1e-27 97.3 13.2 1.2e-27 97.0 13.2 1.0 1 0 0 1 1 1 1 ZIP Zinc transporter Amastin PF07344.11 CBZ41019.1 - 5e-47 159.6 10.6 6e-47 159.4 10.6 1.1 1 0 0 1 1 1 1 Amastin surface glycoprotein DUF805 PF05656.14 CBZ41019.1 - 0.19 12.1 9.9 0.027 14.9 5.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF805) LRR_8 PF13855.6 CBZ41023.1 - 9.4e-06 25.3 0.0 0.032 14.0 0.1 3.0 2 1 3 5 5 5 4 Leucine rich repeat LRR_4 PF12799.7 CBZ41023.1 - 0.0032 17.8 0.9 0.55 10.7 0.2 3.1 2 1 1 3 3 3 1 Leucine Rich repeats (2 copies) DUF3338 PF11819.8 CBZ41023.1 - 0.19 11.7 0.0 6.4 6.8 0.0 2.8 1 1 2 3 3 3 0 Domain of unknown function (DUF3338) Per1 PF04080.13 CBZ41024.1 - 0.016 15.0 0.0 0.019 14.7 0.0 1.2 1 0 0 1 1 1 0 Per1-like family DUF1515 PF07439.11 CBZ41024.1 - 0.096 12.7 4.5 0.55 10.3 2.3 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1515) Phg_2220_C PF09524.10 CBZ41024.1 - 0.41 10.7 3.3 2.4 8.3 0.1 2.3 1 1 1 2 2 2 0 Conserved phage C-terminus (Phg_2220_C) Amastin PF07344.11 CBZ41025.1 - 8.9e-52 175.0 7.1 1.1e-51 174.8 7.1 1.1 1 0 0 1 1 1 1 Amastin surface glycoprotein Amastin PF07344.11 CBZ41026.1 - 7.9e-54 181.7 10.1 9.4e-54 181.5 10.1 1.1 1 0 0 1 1 1 1 Amastin surface glycoprotein DUF3087 PF11286.8 CBZ41026.1 - 0.14 11.6 0.2 0.28 10.7 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3087) Vpu PF00558.19 CBZ41026.1 - 0.26 11.1 0.2 0.26 11.1 0.2 2.6 3 0 0 3 3 3 0 Vpu protein SUR7 PF06687.12 CBZ41026.1 - 0.75 9.4 16.5 1.1 8.8 11.0 2.3 2 1 0 2 2 2 0 SUR7/PalI family Peptidase_C2 PF00648.21 CBZ41027.1 - 4.8e-41 140.7 0.0 6.6e-41 140.3 0.0 1.1 1 0 0 1 1 1 1 Calpain family cysteine protease IMS PF00817.20 CBZ41028.1 - 4.3e-30 104.7 0.1 5.3e-30 104.4 0.1 1.1 1 0 0 1 1 1 1 impB/mucB/samB family TIP39 PF14980.6 CBZ41028.1 - 0.24 11.3 0.1 0.24 11.3 0.1 1.7 2 0 0 2 2 2 0 TIP39 peptide IMS PF00817.20 CBZ41029.1 - 1.6e-38 132.1 0.2 2.2e-38 131.6 0.2 1.2 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.8 CBZ41029.1 - 0.00077 20.1 0.0 0.0025 18.5 0.0 1.9 2 0 0 2 2 2 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.8 CBZ41029.1 - 0.009 16.3 0.0 0.018 15.4 0.0 1.5 1 0 0 1 1 1 1 IMS family HHH motif BT1 PF03092.16 CBZ41030.1 - 7.1e-255 846.2 5.8 8.2e-255 846.0 5.8 1.0 1 0 0 1 1 1 1 BT1 family LRR_8 PF13855.6 CBZ41031.1 - 2.7e-09 36.7 0.1 0.00047 19.9 0.1 3.0 2 2 0 2 2 2 2 Leucine rich repeat LRRNT_2 PF08263.12 CBZ41031.1 - 0.057 13.7 0.1 0.057 13.7 0.1 2.8 4 0 0 4 4 4 0 Leucine rich repeat N-terminal domain ATP-synt_ab PF00006.25 CBZ41032.1 - 3.2e-67 226.3 0.1 4.9e-67 225.7 0.1 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.27 CBZ41032.1 - 1.2e-08 35.3 0.8 8.3e-08 32.6 0.0 2.2 2 0 0 2 2 2 1 ATP synthase alpha/beta chain, C terminal domain His_kinase PF06580.13 CBZ41032.1 - 0.92 9.9 4.3 0.93 9.9 0.3 2.4 1 1 1 2 2 2 0 Histidine kinase ECH_2 PF16113.5 CBZ41033.1 - 7.5e-91 305.1 0.0 8.5e-91 304.9 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_1 PF00378.20 CBZ41033.1 - 1.6e-16 60.4 0.0 2.4e-16 59.8 0.0 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Tubulin_C PF03953.17 CBZ41034.1 - 4.6e-34 117.3 0.0 6.1e-34 116.9 0.0 1.2 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin PF00091.25 CBZ41035.1 - 6.5e-66 222.3 0.0 7.7e-66 222.0 0.0 1.1 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 CBZ41035.1 - 1.2e-07 32.0 0.1 2.2e-07 31.1 0.1 1.5 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 CBZ41035.1 - 0.0053 16.5 0.0 0.007 16.1 0.0 1.3 1 0 0 1 1 1 1 Tubulin domain ELO PF01151.18 CBZ41036.1 - 8.2e-58 195.9 14.8 1.3e-57 195.2 14.8 1.3 1 0 0 1 1 1 1 GNS1/SUR4 family ELO PF01151.18 CBZ41037.1 - 5.2e-73 245.7 20.1 7.4e-73 245.1 20.1 1.2 1 0 0 1 1 1 1 GNS1/SUR4 family ELO PF01151.18 CBZ41038.1 - 3.8e-70 236.3 19.6 5.4e-70 235.8 19.6 1.2 1 0 0 1 1 1 1 GNS1/SUR4 family DUF373 PF04123.13 CBZ41039.1 - 0.029 13.8 0.6 0.037 13.5 0.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF373) Amastin PF07344.11 CBZ41042.1 - 3.7e-48 163.3 9.3 4.3e-48 163.1 9.3 1.0 1 0 0 1 1 1 1 Amastin surface glycoprotein PMP22_Claudin PF00822.20 CBZ41042.1 - 0.055 13.3 5.9 0.078 12.8 5.9 1.3 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin family DUF1218 PF06749.12 CBZ41042.1 - 2.4 8.7 16.4 6.6 7.3 0.6 3.7 2 1 1 3 3 3 0 Protein of unknown function (DUF1218) FA_desaturase PF00487.24 CBZ41042.1 - 8.7 6.1 8.2 8.5 6.1 6.7 1.8 1 1 0 1 1 1 0 Fatty acid desaturase Amastin PF07344.11 CBZ41043.1 - 1.2e-49 168.1 11.6 1.4e-49 167.9 11.6 1.0 1 0 0 1 1 1 1 Amastin surface glycoprotein PMP22_Claudin PF00822.20 CBZ41043.1 - 0.039 13.8 10.3 0.053 13.4 10.3 1.3 1 1 0 1 1 1 0 PMP-22/EMP/MP20/Claudin family DUF1218 PF06749.12 CBZ41043.1 - 0.14 12.7 17.6 0.94 10.0 7.1 3.4 2 1 1 3 3 3 0 Protein of unknown function (DUF1218) FGFR3_TM PF18123.1 CBZ41043.1 - 8.7 6.0 9.2 1.5 8.5 0.2 3.2 3 0 0 3 3 3 0 Fibroblast growth factor receptor 3 transmembrane domain RMI2 PF16100.5 CBZ41044.1 - 0.011 15.5 0.1 0.028 14.2 0.0 1.6 2 0 0 2 2 2 0 RecQ-mediated genome instability protein 2 Pkinase PF00069.25 CBZ41045.1 - 1.9e-62 211.1 0.0 2.2e-62 210.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ41045.1 - 1.2e-25 90.3 0.0 1.6e-25 89.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CBZ41045.1 - 2.8e-09 36.7 0.0 5.3e-09 35.8 0.0 1.4 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.14 CBZ41045.1 - 0.00011 21.6 0.6 0.00021 20.7 0.6 1.4 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 CBZ41045.1 - 0.017 14.7 0.0 0.026 14.1 0.0 1.2 1 0 0 1 1 1 0 RIO1 family APH PF01636.23 CBZ41045.1 - 0.075 12.9 0.4 0.62 9.9 0.2 2.0 1 1 1 2 2 2 0 Phosphotransferase enzyme family Haspin_kinase PF12330.8 CBZ41045.1 - 0.13 11.2 0.2 0.18 10.7 0.2 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Amastin PF07344.11 CBZ41047.1 - 1.4e-53 180.9 7.0 1.7e-53 180.7 7.0 1.1 1 0 0 1 1 1 1 Amastin surface glycoprotein DUF4220 PF13968.6 CBZ41047.1 - 0.7 9.2 2.4 1.2 8.5 2.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4220) Claudin_2 PF13903.6 CBZ41047.1 - 1.4 8.6 12.1 0.078 12.7 4.4 2.4 1 1 1 3 3 3 0 PMP-22/EMP/MP20/Claudin tight junction DUF4407 PF14362.6 CBZ41047.1 - 2.1 7.6 4.5 3.3 7.0 4.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Peptidase_C1 PF00112.23 CBZ41048.1 - 2.7e-71 240.1 0.7 2.7e-71 240.1 0.7 1.9 2 0 0 2 2 2 1 Papain family cysteine protease DUF3586 PF12131.8 CBZ41048.1 - 7.3e-21 74.2 8.8 1.7e-20 73.0 8.8 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3586) Peptidase_C1_2 PF03051.15 CBZ41048.1 - 4.1e-06 25.8 0.2 0.00059 18.7 0.1 2.1 2 0 0 2 2 2 2 Peptidase C1-like family Amastin PF07344.11 CBZ41050.1 - 5.9e-49 165.9 13.1 5.9e-49 165.9 13.1 2.1 3 0 0 3 3 3 1 Amastin surface glycoprotein Phage_holin_3_6 PF07332.11 CBZ41050.1 - 0.046 13.8 0.9 0.046 13.8 0.9 2.5 2 0 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III RMI2 PF16100.5 CBZ41051.1 - 0.011 15.5 0.1 0.028 14.2 0.0 1.6 2 0 0 2 2 2 0 RecQ-mediated genome instability protein 2 Aa_trans PF01490.18 CBZ41052.1 - 4.9e-46 157.3 18.7 5.9e-46 157.0 18.7 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 CBZ41052.1 - 5e-09 35.7 9.4 5e-09 35.7 9.4 2.5 2 1 0 2 2 2 1 Tryptophan/tyrosine permease family # # Program: hmmscan # Version: 3.2.1 (June 2018) # Pipeline mode: SCAN # Query file: /oak/stanford/groups/akundaje/marinovg/genomes/Kinetoplastida/Leishmania_mexicana-ASM23466v4/GCA_000234665.4_ASM23466v4_protein.faa # Target file: /oak/stanford/groups/akundaje/marinovg/genomes/PFam/PFam32.0/Pfam-A.hmm # Option settings: /oak/stanford/groups/akundaje/marinovg/programs/hmmer-3.2.1/bin/hmmscan -o /oak/stanford/groups/akundaje/marinovg/genomes/Kinetoplastida/Leishmania_mexicana-ASM23466v4/GCA_000234665.4_ASM23466v4_protein.PFam32-A --tblout /oak/stanford/groups/akundaje/marinovg/genomes/Kinetoplastida/Leishmania_mexicana-ASM23466v4/GCA_000234665.4_ASM23466v4_protein.PFam32-A.tblout --cpu 20 /oak/stanford/groups/akundaje/marinovg/genomes/PFam/PFam32.0/Pfam-A.hmm /oak/stanford/groups/akundaje/marinovg/genomes/Kinetoplastida/Leishmania_mexicana-ASM23466v4/GCA_000234665.4_ASM23466v4_protein.faa # Current dir: /oak/stanford/groups/akundaje/marinovg/genomes # Date: Mon Mar 25 08:41:13 2019 # [ok]